A0A077ZF06_TRITR Loading...

Transmembrane protein 104 protein

AlphaFold DB , UniProt , Accession A0A077ZF06, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 537 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.9	Very low	67.7	Low	241 Å²	241	100.9 Å²	100.9	100%	1.187	56%	0.559	S	S	*	*				0	105.7	0	-85.7	156.6	165.4	0	0	107.3	D3	M1-D3 PolarHBondContact O-N 3.38Å
2	T	34.2	Very low	69.2	Low	139 Å²	139	92.5 Å²	92.5	85%	0.853	51%	0.513	S	S	*	.	P	Polyproline II helix	trans	-67.3	120.4	163.7	45.3	0	0	0	0	106.6
3	D	41.2	Very low	70.9	Confident	138 Å²	138	86.4 Å²	86.4	74%	0.738	48%	0.478	S	S	*	.	P	Polyproline II helix	trans	-49.8	129.6	176.1	-76.2	-36.5	0	0	0	109.2	M1 V5	M1-D3 PolarHBondContact O-N 3.38Å; D3-V5 PolarHBondContact O-N 3.47Å; D3-V5 VanDerWaalsContact O-N 3.14Å
4	P	56.7	Low	72.1	Confident	74 Å²	74	85.5 Å²	85.5	48%	0.481	48%	0.476	S	S	.	.	P	Polyproline II helix	trans	-55.4	127	176.9	23	-31.5	0	0	0	107.5	Q6	P4-Q6 VanDerWaalsContact O-CG 3.28Å; P4-Q6 WeakPolarHBondContact O-CG 3.42Å; P4-Q6 PolarHBondContact O-N 3.22Å
5	V	67.1	Low	73.1	Confident	128 Å²	128	84.5 Å²	84.5	78%	0.776	46%	0.463	S	S	*	.			trans	-50.9	102.5	-175.9	179	0	0	0	0	109.6	D3	D3-V5 PolarHBondContact O-N 3.47Å; D3-V5 VanDerWaalsContact O-N 3.14Å
6	Q	78.4	Confident	74.2	Confident	96 Å²	96	79.3 Å²	79.3	45%	0.449	44%	0.435	S	S	.	.			trans	-85.7	142.9	180	-61.4	-175.7	-17.1	0	0	109.8	P4 P298 K300	P4-Q6 VanDerWaalsContact O-CG 3.28Å; P4-Q6 WeakPolarHBondContact O-CG 3.42Å; P4-Q6 PolarHBondContact O-N 3.22Å; Q6-P298 CarbonylContact C-O 3.58Å; Q6-P298 VanDerWaalsContact CA-O 3.23Å; Q6-P298 WeakPolarHBondContact CA-O 3.47Å; Q6-K300 HydrophobicContact CB-CD 4.41Å; Q6-K300 HydrophobicContact CB-CG 3.53Å; Q6-K300 WeakPolarHBondContact O-CE 3.42Å
7	Y	84.2	Confident	75.1	Confident	41 Å²	41	75.3 Å²	75.3	16%	0.161	42%	0.416	C	S	.	.	B	Isolated β-bridge	trans	-123.9	166.9	178.6	56.2	-110.8	0	0	0	112.7	T11 Y15 I295 P298 M299 K300	Y7-T11 HydrophobicContact CD2-CG2 4.09Å; Y7-T11 HydrophobicContact CG-CG2 4.09Å; Y7-Y15 HydrophobicContact CD1-CE2 4.29Å; Y7-Y15 HydrophobicContact CE1-CD2 4.2Å; Y7-Y15 AromaticContact CE1-CE2 3.96Å; Y7-Y15 HydrophobicContact CE1-CE2 3.96Å; Y7-Y15 HydrophobicContact CE2-CD2 4.25Å; Y7-Y15 AromaticContact CZ-CD2 3.82Å; Y7-I295 VanDerWaalsContact OH-CA 3.31Å; Y7-I295 WeakPolarHBondContact OH-CA 3.4Å; Y7-I295 PolarHBondContact OH-O 2.88Å; Y7-P298 HydrophobicContact CD1-CB 4.07Å; Y7-P298 HydrophobicContact CD1-CG 4.25Å; Y7-P298 HydrophobicContact CE1-CB 3.66Å; Y7-P298 HydrophobicContact CE1-CG 3.36Å; Y7-P298 HydrophobicContact CE2-CG 4.42Å; Y7-P298 PolarHBondContact N-O 3.49Å; Y7-P298 WeakPolarHBondContact OH-CG 3.19Å; Y7-M299 HydrophobicContact CD2-CG 4.17Å; Y7-M299 HydrophobicContact CE2-CG 3.61Å; Y7-M299 WeakPolarHBondContact O-CA 3.38Å; Y7-K300 WeakPolarHBondContact O-CG 3.45Å; Y7-K300 PolarHBondContact O-N 3.44Å
8	S	88.2	Confident	75.9	Confident	56 Å²	56	72.7 Å²	72.7	39%	0.392	40%	0.401	S	S	.	.			trans	-70	155	-177.8	75.6	0	0	0	0	112	L10 T11 G12	S8-L10 PolarHBondContact O-N 3.1Å; S8-T11 WeakPolarHBondContact O-CB 3.26Å; S8-T11 PolarHBondContact O-N 2.9Å; S8-T11 PolarHBondContact OG-N 3.33Å; S8-T11 PolarHBondContact OG-OG1 3.3Å; S8-T11 VanDerWaalsContact OG-OG1 3.05Å; S8-G12 PolarHBondContact O-N 3.38Å; S8-G12 VanDerWaalsContact O-N 3.11Å
9	A	86.9	Confident	76.5	Confident	13 Å²	13	72.1 Å²	72.1	11%	0.107	40%	0.397	C	S	.	.	H	α-helix	trans	-56.8	-36.2	177.2	0	0	0	0	0	112.7	G12 M13 M299 L308	A9-G12 PolarHBondContact O-N 2.79Å; A9-M13 WeakPolarHBondContact O-CG 3.42Å; A9-M13 PolarHBondContact O-N 2.64Å; A9-M299 HydrophobicContact CB-CE 3.59Å; A9-L308 HydrophobicContact CB-CD1 3.82Å
10	L	86.7	Confident	77.3	Confident	133 Å²	133	68.7 Å²	68.7	70%	0.696	38%	0.378	S	S	*	.	H	α-helix	trans	-60.7	-45.7	175.3	-178.3	63	0	0	0	111.8	S8 G12 M13 T14	S8-L10 PolarHBondContact O-N 3.1Å; L10-G12 VanDerWaalsContact C-N 3.29Å; L10-G12 PolarHBondContact O-N 2.91Å; L10-M13 PolarHBondContact O-N 3.08Å; L10-T14 PolarHBondContact O-N 3.23Å; L10-T14 PolarHBondContact O-OG1 3.4Å; L10-T14 VanDerWaalsContact O-OG1 3.08Å
11	T	86.5	Confident	77.8	Confident	51 Å²	51	65.4 Å²	65.4	31%	0.313	36%	0.36	S	S	.	.	H	α-helix	trans	-60.6	-40.2	176.1	-57.3	0	0	0	0	111.5	Y7 S8 T14 Y15	Y7-T11 HydrophobicContact CD2-CG2 4.09Å; Y7-T11 HydrophobicContact CG-CG2 4.09Å; S8-T11 WeakPolarHBondContact O-CB 3.26Å; S8-T11 PolarHBondContact O-N 2.9Å; S8-T11 PolarHBondContact OG-N 3.33Å; S8-T11 PolarHBondContact OG-OG1 3.3Å; S8-T11 VanDerWaalsContact OG-OG1 3.05Å; T11-T14 PolarHBondContact O-N 3.13Å; T11-Y15 HydrophobicContact CG2-CD2 4.08Å; T11-Y15 HydrophobicContact CG2-CE2 3.51Å; T11-Y15 VanDerWaalsContact O-CD2 3.27Å; T11-Y15 WeakPolarHBondContact O-CD2 2.98Å; T11-Y15 PolarHBondContact O-N 3.13Å
12	G	86	Confident	80	Confident	0 Å²	0	54.7 Å²	54.7	0%	0	31%	0.311	C	S	.	.	H	α-helix	trans	-61.4	-44.1	173.7	0	0	0	0	0	113.2	S8 A9 L10 T14 Y15 L16 I295	S8-G12 PolarHBondContact O-N 3.38Å; S8-G12 VanDerWaalsContact O-N 3.11Å; A9-G12 PolarHBondContact O-N 2.79Å; L10-G12 VanDerWaalsContact C-N 3.29Å; L10-G12 PolarHBondContact O-N 2.91Å; G12-T14 VanDerWaalsContact C-N 3.34Å; G12-T14 PolarHBondContact O-N 3.11Å; G12-Y15 PolarHBondContact O-N 2.97Å; G12-L16 PolarHBondContact O-N 3.5Å; G12-I295 WeakPolarHBondContact O-CG2 3.33Å
13	M	90.5	Very high	82.3	Confident	13 Å²	13	48.5 Å²	48.5	6%	0.064	27%	0.273	C	S	.	.	H	α-helix	trans	-65.8	-35.3	176.6	-67.1	-51.6	103.9	0	0	112.5	A9 L10 L16 G17 M299 L308 V309 V312	A9-M13 WeakPolarHBondContact O-CG 3.42Å; A9-M13 PolarHBondContact O-N 2.64Å; L10-M13 PolarHBondContact O-N 3.08Å; M13-L16 PolarHBondContact O-N 2.88Å; M13-L16 HydrophobicContact SD-CD2 4.28Å; M13-G17 PolarHBondContact O-N 2.97Å; M13-M299 HydrophobicContact CE-CE 3.66Å; M13-M299 HydrophobicContact CE-SD 3.91Å; M13-L308 HydrophobicContact CG-CB 3.85Å; M13-L308 HydrophobicContact CG-CD1 4.47Å; M13-L308 HydrophobicContact SD-CB 3.68Å; M13-V309 HydrophobicContact CE-CG2 4Å; M13-V309 HydrophobicContact SD-CG2 3.82Å; M13-V312 HydrophobicContact CB-CG2 3.74Å; M13-V312 HydrophobicContact CG-CG2 4.13Å; M13-V312 HydrophobicContact SD-CG2 3.87Å
14	T	87.9	Confident	84.5	Confident	74 Å²	74	42 Å²	42	45%	0.454	24%	0.239	S	C	.	.	H	α-helix	trans	-63.9	-42.3	171.6	-54.7	0	0	0	0	111.5	L10 T11 G12 L16 G17 N18	L10-T14 PolarHBondContact O-N 3.23Å; L10-T14 PolarHBondContact O-OG1 3.4Å; L10-T14 VanDerWaalsContact O-OG1 3.08Å; T11-T14 PolarHBondContact O-N 3.13Å; G12-T14 VanDerWaalsContact C-N 3.34Å; G12-T14 PolarHBondContact O-N 3.11Å; T14-L16 VanDerWaalsContact C-N 3.34Å; T14-G17 PolarHBondContact O-N 3Å; T14-N18 WeakPolarHBondContact O-CB 3.31Å; T14-N18 PolarHBondContact O-N 3.48Å; T14-N18 PolarHBondContact O-ND2 2.63Å
15	Y	86.8	Confident	86.3	Confident	71 Å²	71	38.5 Å²	38.5	28%	0.278	22%	0.216	S	C	.	.	H	α-helix	trans	-63	-40.9	173.8	-70.1	-46.8	0	0	0	112	Y7 T11 G12 N18 L19 Y237	Y7-Y15 HydrophobicContact CD1-CE2 4.29Å; Y7-Y15 HydrophobicContact CE1-CD2 4.2Å; Y7-Y15 AromaticContact CE1-CE2 3.96Å; Y7-Y15 HydrophobicContact CE1-CE2 3.96Å; Y7-Y15 HydrophobicContact CE2-CD2 4.25Å; Y7-Y15 AromaticContact CZ-CD2 3.82Å; T11-Y15 HydrophobicContact CG2-CD2 4.08Å; T11-Y15 HydrophobicContact CG2-CE2 3.51Å; T11-Y15 VanDerWaalsContact O-CD2 3.27Å; T11-Y15 WeakPolarHBondContact O-CD2 2.98Å; T11-Y15 PolarHBondContact O-N 3.13Å; G12-Y15 PolarHBondContact O-N 2.97Å; Y15-N18 PolarHBondContact O-N 3.43Å; Y15-L19 WeakPolarHBondContact O-CB 3.41Å; Y15-L19 PolarHBondContact O-N 2.85Å; Y15-Y237 PolarHBondContact OH-OH 2.95Å
16	L	90.6	Very high	87.5	Confident	1 Å²	1	32.7 Å²	32.7	1%	0.005	18%	0.181	C	C	.	.	H	α-helix	trans	-63.2	-46.1	176	-177.9	61.6	0	0	0	112	G12 M13 T14 N18 L19 L20 C288 L292 I295 V309 V312	G12-L16 PolarHBondContact O-N 3.5Å; M13-L16 PolarHBondContact O-N 2.88Å; M13-L16 HydrophobicContact SD-CD2 4.28Å; T14-L16 VanDerWaalsContact C-N 3.34Å; L16-N18 PolarHBondContact O-N 2.82Å; L16-L19 WeakPolarHBondContact O-CB 3.22Å; L16-L19 PolarHBondContact O-N 2.73Å; L16-L20 HydrophobicContact CG-CD1 4.31Å; L16-L20 WeakPolarHBondContact O-CG 3.39Å; L16-L20 PolarHBondContact O-N 3.12Å; L16-C288 HydrophobicContact CD1-CB 4.02Å; L16-L292 HydrophobicContact CD1-CD1 4.2Å; L16-I295 HydrophobicContact CB-CD1 4.48Å; L16-I295 HydrophobicContact CD1-CD1 4.39Å; L16-V309 HydrophobicContact CD2-CB 4.36Å; L16-V309 HydrophobicContact CD2-CG1 3.88Å; L16-V309 HydrophobicContact CD2-CG2 3.9Å; L16-V312 HydrophobicContact CD2-CB 4.47Å; L16-V312 HydrophobicContact CD2-CG1 4.26Å; L16-V312 HydrophobicContact CG-CG1 4.15Å
17	G	91	Very high	88.3	Confident	11 Å²	11	28.1 Å²	28.1	11%	0.113	16%	0.159	C	C	.	.	H	α-helix	trans	-62.1	-42.3	176.1	0	0	0	0	0	112.4	M13 T14 L19 L20 V21	M13-G17 PolarHBondContact O-N 2.97Å; T14-G17 PolarHBondContact O-N 3Å; G17-L19 VanDerWaalsContact C-N 3.31Å; G17-L19 PolarHBondContact O-N 3.44Å; G17-L20 PolarHBondContact O-N 3.36Å; G17-V21 WeakPolarHBondContact O-CB 3.38Å; G17-V21 WeakPolarHBondContact O-CG2 3.47Å; G17-V21 PolarHBondContact O-N 2.98Å
18	N	87.9	Confident	88.8	Confident	28 Å²	28	26.1 Å²	26.1	15%	0.15	15%	0.152	C	C	.	.	H	α-helix	trans	-67.5	-29.3	175.1	-79.5	-24.9	0	0	0	113.4	T14 Y15 L16 S240 R243 W244	T14-N18 WeakPolarHBondContact O-CB 3.31Å; T14-N18 PolarHBondContact O-N 3.48Å; T14-N18 PolarHBondContact O-ND2 2.63Å; Y15-N18 PolarHBondContact O-N 3.43Å; L16-N18 PolarHBondContact O-N 2.82Å; N18-S240 PolarHBondContact ND2-OG 3.28Å; N18-S240 PolarHBondContact OD1-OG 3.22Å; N18-R243 PolarHBondContact O-NH1 3.35Å; N18-W244 PolarHBondContact OD1-NE1 2.88Å
19	L	87.9	Confident	89.1	Confident	62 Å²	62	23.5 Å²	23.5	33%	0.325	13%	0.133	S	C	.	.	H	α-helix	trans	-70.6	-45.8	174.4	178.9	70.3	0	0	0	110.4	Y15 L16 G17 C288 I295	Y15-L19 WeakPolarHBondContact O-CB 3.41Å; Y15-L19 PolarHBondContact O-N 2.85Å; L16-L19 WeakPolarHBondContact O-CB 3.22Å; L16-L19 PolarHBondContact O-N 2.73Å; G17-L19 VanDerWaalsContact C-N 3.31Å; G17-L19 PolarHBondContact O-N 3.44Å; L19-C288 HydrophobicContact CD2-CB 3.7Å; L19-C288 HydrophobicContact CG-CB 4.41Å; L19-I295 HydrophobicContact CD2-CD1 3.83Å
20	L	92.1	Very high	89.4	Confident	4 Å²	4	24.9 Å²	24.9	2%	0.021	14%	0.135	C	C	.	.	H	α-helix	trans	-63.2	-51.3	177.7	-72	167.1	0	0	0	110.8	L16 G17 G22 F286 C288 V312 Y313 V316 Y320	L16-L20 HydrophobicContact CG-CD1 4.31Å; L16-L20 WeakPolarHBondContact O-CG 3.39Å; L16-L20 PolarHBondContact O-N 3.12Å; G17-L20 PolarHBondContact O-N 3.36Å; L20-G22 VanDerWaalsContact C-N 3.31Å; L20-G22 PolarHBondContact O-N 3.43Å; L20-F286 HydrophobicContact CD2-CD1 4.47Å; L20-C288 HydrophobicContact CD2-CB 3.83Å; L20-C288 HydrophobicContact CG-CB 4.3Å; L20-V312 HydrophobicContact CD1-CG1 3.98Å; L20-Y313 HydrophobicContact CD1-CE2 4.38Å; L20-V316 HydrophobicContact CB-CG1 4.19Å; L20-V316 HydrophobicContact CB-CG2 4.14Å; L20-V316 HydrophobicContact CD1-CG2 4.08Å; L20-Y320 VanDerWaalsContact C-OH 3.32Å; L20-Y320 PolarHBondContact O-OH 2.97Å
21	V	88.5	Confident	89.7	Confident	0 Å²	0	18.6 Å²	18.6	0%	0	10%	0.103	C	C	.	.	S	Bend	trans	-74.2	84.4	179.5	-177.3	0	0	0	0	109.8	G17 R243 W244 F247 V316 F319 Y320	G17-V21 WeakPolarHBondContact O-CB 3.38Å; G17-V21 WeakPolarHBondContact O-CG2 3.47Å; G17-V21 PolarHBondContact O-N 2.98Å; V21-R243 WeakPolarHBondContact O-CD 3.47Å; V21-R243 PolarHBondContact O-NE 3.42Å; V21-R243 PolarHBondContact O-NH1 3.19Å; V21-W244 HydrophobicContact CB-CZ2 4.48Å; V21-W244 HydrophobicContact CG2-CH2 4.06Å; V21-W244 HydrophobicContact CG2-CZ2 4.27Å; V21-F247 HydrophobicContact CG1-CD2 3.93Å; V21-F247 HydrophobicContact CG1-CE2 3.61Å; V21-F247 HydrophobicContact CG1-CZ 4.48Å; V21-V316 HydrophobicContact CG2-CG1 4.37Å; V21-V316 HydrophobicContact CG2-CG2 4.04Å; V21-F319 HydrophobicContact CG1-CD1 4.29Å; V21-F319 HydrophobicContact CG1-CE1 3.67Å; V21-F319 HydrophobicContact CG1-CZ 4.28Å; V21-F319 HydrophobicContact CG2-CD1 4.06Å; V21-F319 HydrophobicContact CG2-CE1 4.27Å; V21-Y320 HydrophobicContact CG2-CE1 4.46Å
22	G	81.6	Confident	90.1	Very high	16 Å²	16	16.1 Å²	16.1	17%	0.165	9%	0.088	C	C	.	.	S	Bend	trans	-122.4	-144.2	-179	0	0	0	0	0	113.4	L20 G24	L20-G22 VanDerWaalsContact C-N 3.31Å; L20-G22 PolarHBondContact O-N 3.43Å; G22-G24 VanDerWaalsContact C-N 3.33Å
23	T	82.2	Confident	90.4	Very high	9 Å²	9	17.5 Å²	17.5	6%	0.055	9%	0.094	C	C	.	.	S	Bend	trans	-68	-28.7	178.5	39.7	0	0	0	0	113.3	A25 L26 Y159 Y284 I371	T23-A25 PolarHBondContact O-N 3.19Å; T23-L26 WeakPolarHBondContact O-CB 3.34Å; T23-L26 PolarHBondContact O-N 2.95Å; T23-Y159 HydrophobicContact CG2-CD1 4.06Å; T23-Y159 HydrophobicContact CG2-CE1 3.47Å; T23-Y159 VanDerWaalsContact CG2-CE1 3.47Å; T23-Y284 WeakPolarHBondContact OG1-CE1 3.38Å; T23-Y284 PolarHBondContact OG1-OH 2.98Å; T23-I371 HydrophobicContact CG2-CD1 3.49Å; T23-I371 VanDerWaalsContact CG2-CD1 3.49Å; T23-I371 HydrophobicContact CG2-CG1 3.79Å
24	G	87.4	Confident	90.4	Very high	2 Å²	2	17.9 Å²	17.9	2%	0.021	10%	0.096	C	C	.	.	H	α-helix	trans	-57.3	-36	179.1	0	0	0	0	0	113.2	G22 L26 A27 L28 S285	G22-G24 VanDerWaalsContact C-N 3.33Å; G24-L26 PolarHBondContact O-N 3.05Å; G24-L26 VanDerWaalsContact O-N 3.15Å; G24-A27 PolarHBondContact O-N 3.44Å; G24-A27 VanDerWaalsContact O-N 3.14Å; G24-L28 PolarHBondContact O-N 3.08Å; G24-S285 VanDerWaalsContact C-OG 3.24Å; G24-S285 WeakPolarHBondContact CA-OG 3.48Å; G24-S285 PolarHBondContact O-OG 3.29Å
25	A	93	Very high	90.6	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-59.7	-26.4	176.9	0	0	0	0	0	113.9	T23 P29 F247 F319 Y320	T23-A25 PolarHBondContact O-N 3.19Å; A25-P29 WeakPolarHBondContact O-CD 3.25Å; A25-F247 HydrophobicContact CB-CE1 3.95Å; A25-F247 HydrophobicContact CB-CZ 3.68Å; A25-F319 HydrophobicContact CB-CE1 4.32Å; A25-Y320 HydrophobicContact CB-CD1 4.17Å; A25-Y320 HydrophobicContact CB-CE1 3.64Å
26	L	93.2	Very high	90.9	Very high	5 Å²	5	11 Å²	11	3%	0.026	6%	0.062	C	C	.	.	H	α-helix	trans	-77.3	-22.3	-179.3	-63	174.3	0	0	0	113.2	T23 G24 F247 M250 Y338 V339 Y366 P367	T23-L26 WeakPolarHBondContact O-CB 3.34Å; T23-L26 PolarHBondContact O-N 2.95Å; G24-L26 PolarHBondContact O-N 3.05Å; G24-L26 VanDerWaalsContact O-N 3.15Å; L26-F247 HydrophobicContact CD2-CE1 3.75Å; L26-F247 HydrophobicContact CD2-CZ 4.08Å; L26-F247 HydrophobicContact CG-CE1 4.46Å; L26-F247 HydrophobicContact CG-CZ 4.4Å; L26-M250 HydrophobicContact CD2-CE 4.22Å; L26-Y338 WeakPolarHBondContact O-CB 3.5Å; L26-Y338 PolarHBondContact O-N 3.44Å; L26-V339 HydrophobicContact CD2-CG1 4.02Å; L26-Y366 HydrophobicContact CD1-CE1 4.28Å; L26-Y366 HydrophobicContact CD2-CE1 4.31Å; L26-P367 HydrophobicContact CD1-CG 4.46Å
27	A	94.2	Very high	91	Very high	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-101.4	-17.9	180	0	0	0	0	0	113.1	G24 R30 A31 T281 D336 I467	G24-A27 PolarHBondContact O-N 3.44Å; G24-A27 VanDerWaalsContact O-N 3.14Å; A27-R30 WeakPolarHBondContact O-CB 3.11Å; A27-R30 PolarHBondContact O-N 3.43Å; A27-A31 PolarHBondContact O-N 3.23Å; A27-A31 VanDerWaalsContact O-N 3.15Å; A27-T281 HydrophobicContact CB-CG2 3.87Å; A27-D336 WeakPolarHBondContact CA-O 3.46Å; A27-I467 HydrophobicContact CB-CD1 3.53Å
28	L	95	Very high	91.2	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-54.8	-42.1	179.8	-78.8	174.7	0	0	0	114.4	G24 R30 A31 F32 L44 T281 Y320 S324	G24-L28 PolarHBondContact O-N 3.08Å; L28-R30 VanDerWaalsContact C-N 3.31Å; L28-R30 PolarHBondContact O-N 3.5Å; L28-A31 PolarHBondContact O-N 3.49Å; L28-F32 HydrophobicContact CD2-CE2 4.5Å; L28-F32 VanDerWaalsContact O-CD2 3.29Å; L28-F32 WeakPolarHBondContact O-CD2 3.41Å; L28-F32 PolarHBondContact O-N 2.82Å; L28-L44 HydrophobicContact CD1-CD1 4.41Å; L28-L44 HydrophobicContact CD2-CD1 3.97Å; L28-T281 HydrophobicContact CD2-CG2 3.82Å; L28-T281 HydrophobicContact CG-CG2 4.07Å; L28-Y320 HydrophobicContact CD1-CD1 3.89Å; L28-Y320 HydrophobicContact CD1-CD2 3.71Å; L28-Y320 HydrophobicContact CD1-CE1 4.37Å; L28-Y320 HydrophobicContact CD1-CE2 4.2Å; L28-Y320 HydrophobicContact CD1-CG 3.54Å; L28-S324 WeakPolarHBondContact CB-OG 3.44Å
29	P	94.8	Very high	91.5	Very high	0 Å²	0	18.8 Å²	18.8	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-61.6	-37.6	178.8	-25.9	36.9	0	0	0	113.4	A25 F32 Q33 I323 V334 Y338	A25-P29 WeakPolarHBondContact O-CD 3.25Å; P29-F32 PolarHBondContact O-N 2.88Å; P29-Q33 PolarHBondContact O-N 3.38Å; P29-I323 HydrophobicContact CG-CG1 4.32Å; P29-V334 HydrophobicContact CB-CG1 3.79Å; P29-Y338 HydrophobicContact CB-CD2 3.92Å; P29-Y338 HydrophobicContact CB-CE2 4.17Å; P29-Y338 HydrophobicContact CB-CG 4.26Å; P29-Y338 HydrophobicContact CG-CD1 4.02Å; P29-Y338 HydrophobicContact CG-CD2 3.97Å; P29-Y338 HydrophobicContact CG-CE1 4.33Å; P29-Y338 HydrophobicContact CG-CE2 4.31Å; P29-Y338 HydrophobicContact CG-CG 3.81Å
30	R	93.4	Very high	91.8	Very high	42 Å²	42	15.8 Å²	15.8	16%	0.158	8%	0.079	C	C	.	.	H	α-helix	trans	-62.9	-50.4	174.9	173.9	73.7	-165.8	148	11.9	110.7	A27 L28 F32 Q33 D34 H333 V334 E464	A27-R30 WeakPolarHBondContact O-CB 3.11Å; A27-R30 PolarHBondContact O-N 3.43Å; L28-R30 VanDerWaalsContact C-N 3.31Å; L28-R30 PolarHBondContact O-N 3.5Å; R30-F32 VanDerWaalsContact C-N 3.26Å; R30-F32 PolarHBondContact O-N 2.84Å; R30-Q33 WeakPolarHBondContact O-CA 3.37Å; R30-Q33 WeakPolarHBondContact O-CB 3.41Å; R30-Q33 PolarHBondContact O-N 2.76Å; R30-D34 IonicContact CZ-OD1 3.82Å; R30-D34 IonicContact CZ-OD2 2.67Å; R30-D34 VanDerWaalsContact CZ-OD2 3.29Å; R30-D34 IonicContact NE-OD1 2.94Å; R30-D34 IonicContact NE-OD2 3.76Å; R30-D34 PolarHBondContact NE-OD2 3.4Å; R30-D34 IonicContact NH1-OD1 3.64Å; R30-D34 IonicContact NH2-OD1 3.97Å; R30-D34 PolarHBondContact NH2-OD1 2.87Å; R30-D34 IonicContact NH2-OD2 3.51Å; R30-D34 PolarHBondContact NH2-OD2 3.33Å; R30-D34 PolarHBondContact O-N 3.17Å; R30-H333 PolarHBondContact NH1-CE1 3.11Å; R30-H333 PolarHBondContact NH1-ND1 3.44Å; R30-V334 HydrophobicContact CB-CG1 4.1Å; R30-V334 WeakPolarHBondContact CD-O 3.46Å; R30-V334 PolarHBondContact NH1-O 2.91Å; R30-V334 VanDerWaalsContact NH1-O 3.11Å; R30-E464 VanDerWaalsContact CG-CD 3.47Å; R30-E464 HydrophobicContact CG-CG 4.44Å; R30-E464 WeakPolarHBondContact CG-OE2 3.42Å; R30-E464 IonicContact NE-OE2 3.52Å; R30-E464 PolarHBondContact NE-OE2 3.46Å
31	A	93.4	Very high	92	Very high	1 Å²	1	18.5 Å²	18.5	1%	0.008	9%	0.092	C	C	.	.	H	α-helix	trans	-62.9	-32.9	-179.8	0	0	0	0	0	112.7	A27 L28 A35 L278 T281 E464	A27-A31 PolarHBondContact O-N 3.23Å; A27-A31 VanDerWaalsContact O-N 3.15Å; L28-A31 PolarHBondContact O-N 3.49Å; A31-A35 VanDerWaalsContact O-CB 3.31Å; A31-A35 WeakPolarHBondContact O-CB 3.27Å; A31-A35 PolarHBondContact O-N 2.97Å; A31-L278 HydrophobicContact CB-CB 4.48Å; A31-L278 HydrophobicContact CB-CD1 4.4Å; A31-T281 HydrophobicContact CB-CG2 4.42Å; A31-E464 WeakPolarHBondContact CA-OE1 3.5Å
32	F	94.8	Very high	92.4	Very high	0 Å²	0	21.3 Å²	21.3	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-68.9	-35.8	171.5	-91.1	-124	0	0	0	112.7	L28 P29 R30 G36 G40 I41 L44 L278 L321 L325 V328	L28-F32 HydrophobicContact CD2-CE2 4.5Å; L28-F32 VanDerWaalsContact O-CD2 3.29Å; L28-F32 WeakPolarHBondContact O-CD2 3.41Å; L28-F32 PolarHBondContact O-N 2.82Å; P29-F32 PolarHBondContact O-N 2.88Å; R30-F32 VanDerWaalsContact C-N 3.26Å; R30-F32 PolarHBondContact O-N 2.84Å; F32-G36 CarbonylContact O-C 3.51Å; F32-G36 VanDerWaalsContact O-C 3.28Å; F32-G36 WeakPolarHBondContact O-CA 3.46Å; F32-G36 PolarHBondContact O-N 3.39Å; F32-G40 VanDerWaalsContact CE1-C 3.49Å; F32-G40 VanDerWaalsContact CZ-O 3.31Å; F32-G40 WeakPolarHBondContact CZ-O 3.16Å; F32-I41 HydrophobicContact CE1-CG1 4.37Å; F32-L44 HydrophobicContact CE2-CB 4.28Å; F32-L44 HydrophobicContact CE2-CD2 4.05Å; F32-L44 HydrophobicContact CZ-CB 3.99Å; F32-L44 HydrophobicContact CZ-CD2 3.71Å; F32-L44 HydrophobicContact CZ-CG 4.4Å; F32-L278 HydrophobicContact CD2-CD1 3.61Å; F32-L278 HydrophobicContact CE2-CD1 3.7Å; F32-L321 HydrophobicContact CE1-CD2 4.34Å; F32-L321 HydrophobicContact CZ-CD2 4.25Å; F32-L325 HydrophobicContact CD1-CD2 4.4Å; F32-L325 HydrophobicContact CE1-CD2 4.4Å; F32-V328 HydrophobicContact CB-CG2 3.7Å
33	Q	92.3	Very high	92.9	Very high	28 Å²	28	21.1 Å²	21.1	13%	0.131	11%	0.112	C	C	.	.	H	α-helix	trans	-65.8	-41.2	175.8	-178.1	169.3	80.8	0	0	111.3	P29 R30 V328 F331 R332 V334	P29-Q33 PolarHBondContact O-N 3.38Å; R30-Q33 WeakPolarHBondContact O-CA 3.37Å; R30-Q33 WeakPolarHBondContact O-CB 3.41Å; R30-Q33 PolarHBondContact O-N 2.76Å; Q33-V328 HydrophobicContact CB-CG2 4.1Å; Q33-F331 PolarHBondContact NE2-O 3.23Å; Q33-R332 PolarHBondContact NE2-O 3.33Å; Q33-V334 HydrophobicContact CB-CB 4.42Å; Q33-V334 HydrophobicContact CB-CG2 4.37Å
34	D	91.1	Very high	93.6	Very high	21 Å²	21	20.7 Å²	20.7	11%	0.112	11%	0.109	C	C	.	.	H	α-helix	trans	-75.9	-44.7	-176.6	-75.8	-7.8	0	0	0	113	R30 Q274	R30-D34 IonicContact CZ-OD1 3.82Å; R30-D34 IonicContact CZ-OD2 2.67Å; R30-D34 VanDerWaalsContact CZ-OD2 3.29Å; R30-D34 IonicContact NE-OD1 2.94Å; R30-D34 IonicContact NE-OD2 3.76Å; R30-D34 PolarHBondContact NE-OD2 3.4Å; R30-D34 IonicContact NH1-OD1 3.64Å; R30-D34 IonicContact NH2-OD1 3.97Å; R30-D34 PolarHBondContact NH2-OD1 2.87Å; R30-D34 IonicContact NH2-OD2 3.51Å; R30-D34 PolarHBondContact NH2-OD2 3.33Å; R30-D34 PolarHBondContact O-N 3.17Å; D34-Q274 HydrophobicContact CB-CB 4.12Å; D34-Q274 HydrophobicContact CB-CG 4.24Å
35	A	92.2	Very high	94.1	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-84.3	-20.4	-179.9	0	0	0	0	0	113.6	A31 L39 A270 R271 L278	A31-A35 VanDerWaalsContact O-CB 3.31Å; A31-A35 WeakPolarHBondContact O-CB 3.27Å; A31-A35 PolarHBondContact O-N 2.97Å; A35-L39 HydrophobicContact CB-CD2 4.27Å; A35-A270 CarbonylContact O-C 3.3Å; A35-A270 WeakPolarHBondContact O-CA 3.32Å; A35-R271 PolarHBondContact O-N 3.27Å; A35-L278 HydrophobicContact CB-CB 3.64Å; A35-L278 HydrophobicContact CB-CD2 3.61Å; A35-L278 HydrophobicContact CB-CG 4.17Å
36	G	93.2	Very high	94.2	Very high	1 Å²	1	26.9 Å²	26.9	1%	0.01	14%	0.14	C	C	.	.			trans	93.5	149.8	-178	0	0	0	0	0	114.1	F32 I38 L39 G40 I268 P269	F32-G36 CarbonylContact O-C 3.51Å; F32-G36 VanDerWaalsContact O-C 3.28Å; F32-G36 WeakPolarHBondContact O-CA 3.46Å; F32-G36 PolarHBondContact O-N 3.39Å; G36-I38 PolarHBondContact O-N 3.15Å; G36-L39 PolarHBondContact O-N 3.26Å; G36-G40 PolarHBondContact O-N 3.28Å; G36-I268 CarbonylContact C-O 3.43Å; G36-I268 WeakPolarHBondContact CA-O 3.33Å; G36-P269 CarbonylContact C-O 3.47Å
37	Y	92.5	Very high	94.3	Very high	81 Å²	81	26.7 Å²	26.7	32%	0.318	14%	0.139	S	C	.	.	H	α-helix	trans	-70.8	-33	-166.8	73.6	-85.5	0	0	0	113.9	G40 I41 L267 I268 P269	Y37-G40 PolarHBondContact O-N 3.1Å; Y37-I41 HydrophobicContact CD2-CD1 4.22Å; Y37-I41 WeakPolarHBondContact O-CD1 3.34Å; Y37-I41 WeakPolarHBondContact O-CG1 3.39Å; Y37-I41 PolarHBondContact O-N 2.87Å; Y37-L267 HydrophobicContact CD1-CB 4.27Å; Y37-L267 HydrophobicContact CD1-CD2 4.11Å; Y37-L267 HydrophobicContact CE1-CB 4.32Å; Y37-L267 HydrophobicContact CE1-CD2 4.49Å; Y37-I268 WeakPolarHBondContact CD1-O 2.99Å; Y37-I268 PolarHBondContact N-O 3.08Å; Y37-I268 VanDerWaalsContact N-O 3.13Å; Y37-P269 HydrophobicContact CE1-CB 4.23Å; Y37-P269 PolarHBondContact N-O 3.21Å
38	I	94.2	Very high	94.4	Very high	89 Å²	89	27 Å²	27	46%	0.456	14%	0.142	S	C	.	.	H	α-helix	trans	-69.5	-48.1	179	-58.2	-178.6	0	0	0	109.2	G36 G40 I41 A42 P269	G36-I38 PolarHBondContact O-N 3.15Å; I38-G40 VanDerWaalsContact C-N 3.3Å; I38-G40 PolarHBondContact O-N 2.8Å; I38-I41 PolarHBondContact O-N 3.08Å; I38-A42 WeakPolarHBondContact O-CB 3.17Å; I38-A42 PolarHBondContact O-N 3.36Å; I38-A42 VanDerWaalsContact O-N 3.07Å; I38-P269 VanDerWaalsContact CB-O 3.31Å; I38-P269 WeakPolarHBondContact CB-O 3.5Å; I38-P269 HydrophobicContact CD1-CB 3.83Å; I38-P269 HydrophobicContact CG1-CB 4.32Å; I38-P269 PolarHBondContact N-O 3Å
39	L	93.5	Very high	94.5	Very high	33 Å²	33	30.7 Å²	30.7	17%	0.173	16%	0.158	C	C	.	.	H	α-helix	trans	-61.5	-43.2	175.7	-173.3	59.9	0	0	0	110.4	A35 G36 A42 V43 A270 F275 L278	A35-L39 HydrophobicContact CB-CD2 4.27Å; G36-L39 PolarHBondContact O-N 3.26Å; L39-A42 PolarHBondContact O-N 3.2Å; L39-V43 HydrophobicContact CD1-CG2 3.76Å; L39-V43 HydrophobicContact CG-CG2 4.13Å; L39-V43 VanDerWaalsContact O-CB 3.29Å; L39-V43 WeakPolarHBondContact O-CB 3.22Å; L39-V43 VanDerWaalsContact O-CG2 3.22Å; L39-V43 WeakPolarHBondContact O-CG2 3.4Å; L39-V43 PolarHBondContact O-N 3.16Å; L39-A270 HydrophobicContact CB-CB 4.02Å; L39-F275 HydrophobicContact CD1-CD2 4.42Å; L39-F275 HydrophobicContact CD2-CD2 4.33Å; L39-L278 HydrophobicContact CG-CD2 4.02Å
40	G	95.3	Very high	94.6	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-51.6	-55.2	172.9	0	0	0	0	0	113.4	F32 G36 Y37 I38 A42 L44	F32-G40 VanDerWaalsContact CE1-C 3.49Å; F32-G40 VanDerWaalsContact CZ-O 3.31Å; F32-G40 WeakPolarHBondContact CZ-O 3.16Å; G36-G40 PolarHBondContact O-N 3.28Å; Y37-G40 PolarHBondContact O-N 3.1Å; I38-G40 VanDerWaalsContact C-N 3.3Å; I38-G40 PolarHBondContact O-N 2.8Å; G40-A42 PolarHBondContact O-N 3.21Å; G40-L44 WeakPolarHBondContact O-CB 3.47Å; G40-L44 PolarHBondContact O-N 2.88Å
41	I	96.6	Very high	94.7	Very high	60 Å²	60	28.7 Å²	28.7	31%	0.308	15%	0.15	S	C	.	.	H	α-helix	trans	-60	-48.3	179.7	-67.1	160.9	0	0	0	111	F32 Y37 I38 T45 L321 L325	F32-I41 HydrophobicContact CE1-CG1 4.37Å; Y37-I41 HydrophobicContact CD2-CD1 4.22Å; Y37-I41 WeakPolarHBondContact O-CD1 3.34Å; Y37-I41 WeakPolarHBondContact O-CG1 3.39Å; Y37-I41 PolarHBondContact O-N 2.87Å; I38-I41 PolarHBondContact O-N 3.08Å; I41-T45 VanDerWaalsContact O-CB 3.26Å; I41-T45 WeakPolarHBondContact O-CB 3.48Å; I41-T45 PolarHBondContact O-N 3.49Å; I41-T45 PolarHBondContact O-OG1 2.91Å; I41-L321 HydrophobicContact CB-CD2 4.32Å; I41-L321 HydrophobicContact CG1-CD2 3.96Å; I41-L321 HydrophobicContact CG2-CD2 4.34Å; I41-L325 HydrophobicContact CD1-CD1 4.33Å; I41-L325 HydrophobicContact CD1-CD2 3.98Å; I41-L325 HydrophobicContact CG1-CD1 4.43Å; I41-L325 HydrophobicContact CG1-CD2 4.09Å
42	A	95.7	Very high	94.9	Very high	59 Å²	59	30 Å²	30	49%	0.488	16%	0.156	S	C	.	.	H	α-helix	trans	-63.7	-49.3	-176.8	0	0	0	0	0	111.7	I38 L39 G40 F46	I38-A42 WeakPolarHBondContact O-CB 3.17Å; I38-A42 PolarHBondContact O-N 3.36Å; I38-A42 VanDerWaalsContact O-N 3.07Å; L39-A42 PolarHBondContact O-N 3.2Å; G40-A42 PolarHBondContact O-N 3.21Å; A42-F46 WeakPolarHBondContact O-CB 3.49Å; A42-F46 PolarHBondContact O-N 3.5Å
43	V	94	Very high	95	Very high	13 Å²	13	30 Å²	30	8%	0.079	16%	0.156	C	C	.	.	H	α-helix	trans	-67.2	-45.7	-178.3	171.7	0	0	0	0	111.2	L39 T45 F46 I47 F275 L278	L39-V43 HydrophobicContact CD1-CG2 3.76Å; L39-V43 HydrophobicContact CG-CG2 4.13Å; L39-V43 VanDerWaalsContact O-CB 3.29Å; L39-V43 WeakPolarHBondContact O-CB 3.22Å; L39-V43 VanDerWaalsContact O-CG2 3.22Å; L39-V43 WeakPolarHBondContact O-CG2 3.4Å; L39-V43 PolarHBondContact O-N 3.16Å; V43-T45 VanDerWaalsContact C-N 3.34Å; V43-T45 PolarHBondContact O-N 3.22Å; V43-F46 PolarHBondContact O-N 3.47Å; V43-I47 HydrophobicContact CG1-CD1 3.52Å; V43-I47 HydrophobicContact CG1-CG1 4.26Å; V43-I47 WeakPolarHBondContact O-CB 3.23Å; V43-I47 WeakPolarHBondContact O-CG1 3.41Å; V43-I47 PolarHBondContact O-N 2.9Å; V43-F275 HydrophobicContact CG1-CE2 4.38Å; V43-F275 HydrophobicContact CG2-CD2 4.24Å; V43-F275 HydrophobicContact CG2-CE2 3.67Å; V43-L278 HydrophobicContact CB-CD2 3.94Å; V43-L278 HydrophobicContact CB-CG 4.42Å; V43-L278 HydrophobicContact CG1-CD2 4.19Å; V43-L278 HydrophobicContact CG1-CG 4.18Å; V43-L278 HydrophobicContact CG2-CD2 4.13Å
44	L	96.3	Very high	95.2	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-63.7	-40.7	180	-170.1	73.4	0	0	0	111.6	L28 F32 G40 S48 S282 F286 L317 L321	L28-L44 HydrophobicContact CD1-CD1 4.41Å; L28-L44 HydrophobicContact CD2-CD1 3.97Å; F32-L44 HydrophobicContact CE2-CB 4.28Å; F32-L44 HydrophobicContact CE2-CD2 4.05Å; F32-L44 HydrophobicContact CZ-CB 3.99Å; F32-L44 HydrophobicContact CZ-CD2 3.71Å; F32-L44 HydrophobicContact CZ-CG 4.4Å; G40-L44 WeakPolarHBondContact O-CB 3.47Å; G40-L44 PolarHBondContact O-N 2.88Å; L44-S48 VanDerWaalsContact O-CB 3.31Å; L44-S48 WeakPolarHBondContact O-CB 2.79Å; L44-S48 PolarHBondContact O-N 2.83Å; L44-S282 WeakPolarHBondContact CD1-OG 3.49Å; L44-F286 HydrophobicContact CD1-CD2 4.28Å; L44-F286 HydrophobicContact CD1-CE2 3.61Å; L44-F286 HydrophobicContact CG-CE2 3.98Å; L44-L317 HydrophobicContact CD2-CD1 4.01Å; L44-L317 HydrophobicContact CG-CD1 3.93Å; L44-L321 HydrophobicContact CD2-CD2 3.86Å; L44-L321 HydrophobicContact CD2-CG 4.11Å
45	T	97.4	Very high	95.3	Very high	59 Å²	59	27.7 Å²	27.7	36%	0.362	14%	0.144	S	C	.	.	H	α-helix	trans	-63.6	-45.7	175.9	-58.6	0	0	0	0	111.1	I41 V43 S48 F49 L317	I41-T45 VanDerWaalsContact O-CB 3.26Å; I41-T45 WeakPolarHBondContact O-CB 3.48Å; I41-T45 PolarHBondContact O-N 3.49Å; I41-T45 PolarHBondContact O-OG1 2.91Å; V43-T45 VanDerWaalsContact C-N 3.34Å; V43-T45 PolarHBondContact O-N 3.22Å; T45-S48 WeakPolarHBondContact O-CB 3.43Å; T45-S48 PolarHBondContact O-N 2.65Å; T45-F49 PolarHBondContact O-N 3.01Å; T45-L317 HydrophobicContact CG2-CD2 4.22Å
46	F	95.9	Very high	95.4	Very high	73 Å²	73	27.7 Å²	27.7	32%	0.32	14%	0.144	S	C	.	.	H	α-helix	trans	-65.2	-44.1	178.6	-176.8	-98.9	0	0	0	112.1	A42 V43 S48 F49 M50 W521	A42-F46 WeakPolarHBondContact O-CB 3.49Å; A42-F46 PolarHBondContact O-N 3.5Å; V43-F46 PolarHBondContact O-N 3.47Å; F46-S48 PolarHBondContact O-N 2.7Å; F46-F49 PolarHBondContact O-N 3.47Å; F46-M50 HydrophobicContact CD1-CG 4.02Å; F46-M50 HydrophobicContact CE1-CG 3.51Å; F46-M50 HydrophobicContact CE1-SD 4.37Å; F46-M50 HydrophobicContact CE2-CG 4.21Å; F46-M50 HydrophobicContact CE2-SD 4.43Å; F46-M50 HydrophobicContact CZ-CG 3.63Å; F46-M50 HydrophobicContact CZ-SD 3.93Å; F46-M50 WeakPolarHBondContact O-CG 3.06Å; F46-M50 PolarHBondContact O-N 3.29Å; F46-W521 HydrophobicContact CD1-CD2 4.45Å; F46-W521 HydrophobicContact CD1-CE3 4.45Å; F46-W521 AromaticContact CD1-CH2 3.61Å; F46-W521 HydrophobicContact CD1-CH2 3.61Å; F46-W521 AromaticContact CD1-CZ2 3.6Å; F46-W521 HydrophobicContact CD1-CZ2 3.6Å; F46-W521 HydrophobicContact CD1-CZ3 4.06Å; F46-W521 AromaticContact CE1-CD2 3.53Å; F46-W521 HydrophobicContact CE1-CD2 3.53Å; F46-W521 AromaticContact CE1-CE2 3.52Å; F46-W521 AromaticContact CE1-CE3 3.51Å; F46-W521 HydrophobicContact CE1-CE3 3.51Å; F46-W521 HydrophobicContact CE1-CG 4.27Å; F46-W521 AromaticContact CE1-CH2 3.49Å; F46-W521 HydrophobicContact CE1-CH2 3.49Å; F46-W521 VanDerWaalsContact CE1-CH2 3.49Å; F46-W521 AromaticContact CE1-CZ2 3.51Å; F46-W521 HydrophobicContact CE1-CZ2 3.51Å; F46-W521 AromaticContact CE1-CZ3 3.49Å; F46-W521 HydrophobicContact CE1-CZ3 3.49Å; F46-W521 VanDerWaalsContact CE1-CZ3 3.49Å; F46-W521 HydrophobicContact CZ-CD2 4.31Å; F46-W521 HydrophobicContact CZ-CE3 4.15Å; F46-W521 HydrophobicContact CZ-CZ3 4.33Å
47	I	95.4	Very high	95.5	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-64.1	-40.4	177	-73.4	172.8	0	0	0	111.2	V43 F49 M50 S51 F279 I283 F286 W521	V43-I47 HydrophobicContact CG1-CD1 3.52Å; V43-I47 HydrophobicContact CG1-CG1 4.26Å; V43-I47 WeakPolarHBondContact O-CB 3.23Å; V43-I47 WeakPolarHBondContact O-CG1 3.41Å; V43-I47 PolarHBondContact O-N 2.9Å; I47-F49 VanDerWaalsContact C-N 3.35Å; I47-F49 PolarHBondContact O-N 3.23Å; I47-M50 PolarHBondContact O-N 2.83Å; I47-S51 WeakPolarHBondContact O-CB 3.36Å; I47-S51 PolarHBondContact O-N 3.04Å; I47-F279 HydrophobicContact CD1-CD2 3.82Å; I47-F279 HydrophobicContact CD1-CE2 4.19Å; I47-I283 HydrophobicContact CD1-CG1 4.25Å; I47-I283 HydrophobicContact CG2-CG1 4.16Å; I47-F286 HydrophobicContact CG2-CD2 4.08Å; I47-W521 HydrophobicContact CG1-CZ2 4.16Å
48	S	96.8	Very high	95.6	Very high	8 Å²	8	23.8 Å²	23.8	6%	0.056	13%	0.129	C	C	.	.	H	α-helix	trans	-57.2	-48.5	173.4	178.5	0	0	0	0	111.1	L44 T45 F46 S51 F52	L44-S48 VanDerWaalsContact O-CB 3.31Å; L44-S48 WeakPolarHBondContact O-CB 2.79Å; L44-S48 PolarHBondContact O-N 2.83Å; T45-S48 WeakPolarHBondContact O-CB 3.43Å; T45-S48 PolarHBondContact O-N 2.65Å; F46-S48 PolarHBondContact O-N 2.7Å; S48-S51 WeakPolarHBondContact O-CB 3.34Å; S48-S51 PolarHBondContact O-N 3.41Å; S48-F52 WeakPolarHBondContact O-CB 3.37Å; S48-F52 PolarHBondContact O-N 2.74Å
49	F	96.9	Very high	95.4	Very high	77 Å²	77	19.5 Å²	19.5	34%	0.338	11%	0.107	S	C	.	.	H	α-helix	trans	-61.1	-48.3	176.8	171.8	-100.3	0	0	0	112.1	T45 F46 I47 S51 F52 L53 F509 W514	T45-F49 PolarHBondContact O-N 3.01Å; F46-F49 PolarHBondContact O-N 3.47Å; I47-F49 VanDerWaalsContact C-N 3.35Å; I47-F49 PolarHBondContact O-N 3.23Å; F49-S51 VanDerWaalsContact C-N 3.3Å; F49-S51 PolarHBondContact O-N 3.07Å; F49-F52 PolarHBondContact O-N 3.25Å; F49-L53 HydrophobicContact CE1-CD1 4.06Å; F49-L53 HydrophobicContact CZ-CD1 4.11Å; F49-L53 WeakPolarHBondContact O-CB 3.4Å; F49-L53 PolarHBondContact O-N 3.27Å; F49-F509 HydrophobicContact CE2-CE1 4.04Å; F49-F509 AromaticContact CE2-CZ 3.8Å; F49-F509 HydrophobicContact CE2-CZ 3.8Å; F49-F509 AromaticContact CZ-CE1 3.92Å; F49-F509 HydrophobicContact CZ-CE1 3.92Å; F49-F509 HydrophobicContact CZ-CZ 4.07Å; F49-W514 AromaticContact CE1-CZ3 3.99Å; F49-W514 HydrophobicContact CE1-CZ3 3.99Å; F49-W514 HydrophobicContact CZ-CH2 4.12Å; F49-W514 AromaticContact CZ-CZ3 3.82Å; F49-W514 HydrophobicContact CZ-CZ3 3.82Å
50	M	96.4	Very high	95.4	Very high	0 Å²	0	18 Å²	18	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-63.3	-36.5	178.6	-71.6	-57.9	-69	0	0	112.3	F46 I47 N54 Y480 L517 W521	F46-M50 HydrophobicContact CD1-CG 4.02Å; F46-M50 HydrophobicContact CE1-CG 3.51Å; F46-M50 HydrophobicContact CE1-SD 4.37Å; F46-M50 HydrophobicContact CE2-CG 4.21Å; F46-M50 HydrophobicContact CE2-SD 4.43Å; F46-M50 HydrophobicContact CZ-CG 3.63Å; F46-M50 HydrophobicContact CZ-SD 3.93Å; F46-M50 WeakPolarHBondContact O-CG 3.06Å; F46-M50 PolarHBondContact O-N 3.29Å; I47-M50 PolarHBondContact O-N 2.83Å; M50-N54 PolarHBondContact O-N 3.41Å; M50-N54 PolarHBondContact O-ND2 3.2Å; M50-Y480 HydrophobicContact CB-CE1 3.9Å; M50-L517 HydrophobicContact CE-CG 4.24Å; M50-L517 HydrophobicContact SD-CD2 4.11Å; M50-L517 HydrophobicContact SD-CG 4.36Å; M50-W521 HydrophobicContact CE-CB 3.85Å; M50-W521 HydrophobicContact CE-CG 4.01Å
51	S	96	Very high	95.2	Very high	0 Å²	0	18 Å²	18	0%	0	10%	0.099	C	C	.	.	H	α-helix	trans	-64.3	-48.8	174.9	-175.8	0	0	0	0	111.2	I47 S48 F49 L53 N54 M55 F286 H289 Y313 Q479	I47-S51 WeakPolarHBondContact O-CB 3.36Å; I47-S51 PolarHBondContact O-N 3.04Å; S48-S51 WeakPolarHBondContact O-CB 3.34Å; S48-S51 PolarHBondContact O-N 3.41Å; F49-S51 VanDerWaalsContact C-N 3.3Å; F49-S51 PolarHBondContact O-N 3.07Å; S51-L53 PolarHBondContact O-N 2.91Å; S51-N54 PolarHBondContact O-N 3.43Å; S51-M55 WeakPolarHBondContact O-CB 3.45Å; S51-M55 PolarHBondContact O-N 3.23Å; S51-F286 PolarHBondContact OG-O 3.03Å; S51-H289 PolarHBondContact O-CE1 2.85Å; S51-H289 PolarHBondContact O-NE2 2.75Å; S51-H289 PolarHBondContact OG-CE1 2.81Å; S51-Y313 VanDerWaalsContact OG-CE1 3.28Å; S51-Y313 WeakPolarHBondContact OG-CE1 3.45Å; S51-Y313 PolarHBondContact OG-OH 3.11Å; S51-Q479 PolarHBondContact OG-NE2 3.05Å
52	F	96.4	Very high	94.8	Very high	28 Å²	28	15.3 Å²	15.3	12%	0.123	9%	0.085	C	C	.	.	H	α-helix	trans	-57.9	-47.7	174.4	170.3	-109.9	0	0	0	111.8	S48 F49 N54 M55 T56 V309 A310 Y313 F509	S48-F52 WeakPolarHBondContact O-CB 3.37Å; S48-F52 PolarHBondContact O-N 2.74Å; F49-F52 PolarHBondContact O-N 3.25Å; F52-N54 PolarHBondContact O-N 3.07Å; F52-M55 WeakPolarHBondContact O-CB 3.39Å; F52-M55 PolarHBondContact O-N 3.47Å; F52-M55 VanDerWaalsContact O-N 3.1Å; F52-T56 HydrophobicContact CD2-CG2 4.38Å; F52-T56 HydrophobicContact CE1-CG2 4.18Å; F52-T56 HydrophobicContact CE2-CG2 3.93Å; F52-T56 HydrophobicContact CZ-CG2 3.81Å; F52-T56 VanDerWaalsContact O-CG2 3.29Å; F52-T56 WeakPolarHBondContact O-CG2 3.28Å; F52-T56 PolarHBondContact O-N 3.49Å; F52-V309 HydrophobicContact CD2-CG1 4.05Å; F52-V309 HydrophobicContact CE2-CB 4.35Å; F52-V309 HydrophobicContact CE2-CG1 4.15Å; F52-A310 HydrophobicContact CD2-CB 4.45Å; F52-A310 HydrophobicContact CE1-CB 4.4Å; F52-A310 HydrophobicContact CE2-CB 3.73Å; F52-A310 HydrophobicContact CZ-CB 3.7Å; F52-Y313 HydrophobicContact CB-CD1 4.04Å; F52-Y313 HydrophobicContact CB-CD2 4.18Å; F52-Y313 HydrophobicContact CB-CE1 4.28Å; F52-Y313 HydrophobicContact CB-CE2 4.39Å; F52-Y313 HydrophobicContact CB-CG 3.97Å; F52-Y313 HydrophobicContact CD2-CD2 4.01Å; F52-Y313 HydrophobicContact CD2-CE2 4.43Å; F52-Y313 HydrophobicContact CD2-CG 4.41Å; F52-F509 HydrophobicContact CD1-CE2 4.12Å; F52-F509 HydrophobicContact CD1-CZ 4.4Å; F52-F509 AromaticContact CE1-CE2 3.8Å; F52-F509 HydrophobicContact CE1-CE2 3.8Å; F52-F509 HydrophobicContact CE1-CZ 4.13Å
53	L	96.7	Very high	94.5	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-54.2	-50.8	177.4	177.9	154.1	0	0	0	111.1	F49 S51 M55 T56 F57 F509 W514	F49-L53 HydrophobicContact CE1-CD1 4.06Å; F49-L53 HydrophobicContact CZ-CD1 4.11Å; F49-L53 WeakPolarHBondContact O-CB 3.4Å; F49-L53 PolarHBondContact O-N 3.27Å; S51-L53 PolarHBondContact O-N 2.91Å; L53-M55 VanDerWaalsContact C-N 3.32Å; L53-M55 PolarHBondContact O-N 2.86Å; L53-T56 PolarHBondContact O-N 2.83Å; L53-T56 PolarHBondContact O-OG1 3.04Å; L53-F57 HydrophobicContact CD2-CD2 4.04Å; L53-F57 HydrophobicContact CD2-CE1 4.37Å; L53-F57 HydrophobicContact CD2-CE2 3.24Å; L53-F57 HydrophobicContact CD2-CZ 3.45Å; L53-F57 VanDerWaalsContact CD2-CZ 3.45Å; L53-F57 HydrophobicContact CG-CE2 4.34Å; L53-F57 HydrophobicContact CG-CZ 4.12Å; L53-F57 PolarHBondContact O-N 2.88Å; L53-F509 HydrophobicContact CB-CD2 4.27Å; L53-F509 HydrophobicContact CB-CE2 4.11Å; L53-F509 HydrophobicContact CD1-CD1 4.17Å; L53-F509 HydrophobicContact CD1-CD2 4.36Å; L53-F509 HydrophobicContact CD1-CE1 4.38Å; L53-F509 HydrophobicContact CD1-CG 4.15Å; L53-F509 HydrophobicContact CG-CD2 3.93Å; L53-F509 HydrophobicContact CG-CE2 4.23Å; L53-F509 HydrophobicContact CG-CG 4.12Å; L53-W514 HydrophobicContact CD1-CB 4.27Å; L53-W514 HydrophobicContact CD1-CD2 4.05Å; L53-W514 HydrophobicContact CD1-CE3 3.43Å; L53-W514 VanDerWaalsContact CD1-CE3 3.43Å; L53-W514 HydrophobicContact CD1-CG 4.43Å; L53-W514 HydrophobicContact CD1-CZ3 4.06Å
54	N	96.2	Very high	94.2	Very high	0 Å²	0	12 Å²	12	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-69.8	-29.1	178.8	-78.4	-80.4	0	0	0	113.2	M50 S51 F52 T56 F57 V58 Q479 Y480 P483 T484 S518	M50-N54 PolarHBondContact O-N 3.41Å; M50-N54 PolarHBondContact O-ND2 3.2Å; S51-N54 PolarHBondContact O-N 3.43Å; F52-N54 PolarHBondContact O-N 3.07Å; N54-T56 VanDerWaalsContact C-N 3.26Å; N54-T56 PolarHBondContact O-N 2.72Å; N54-F57 WeakPolarHBondContact O-CB 3.19Å; N54-F57 PolarHBondContact O-N 2.97Å; N54-V58 PolarHBondContact O-N 3.44Å; N54-V58 VanDerWaalsContact O-N 3.15Å; N54-Q479 WeakPolarHBondContact CB-O 3.26Å; N54-Y480 HydrophobicContact CB-CD1 4.47Å; N54-Y480 VanDerWaalsContact ND2-CD1 3.32Å; N54-Y480 WeakPolarHBondContact ND2-CD1 3.3Å; N54-Y480 PolarHBondContact OD1-O 3.47Å; N54-P483 HydrophobicContact CB-CB 4.12Å; N54-P483 HydrophobicContact CB-CG 4.43Å; N54-T484 PolarHBondContact OD1-OG1 3.24Å; N54-T484 VanDerWaalsContact OD1-OG1 3.06Å; N54-S518 VanDerWaalsContact CG-OG 3.25Å; N54-S518 PolarHBondContact ND2-OG 3.1Å; N54-S518 PolarHBondContact OD1-OG 3.05Å
55	M	94.2	Very high	93.8	Very high	0 Å²	0	12 Å²	12	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-61.5	-42	172.8	175.8	-76.4	175	0	0	109.5	S51 F52 L53 F57 V58 V59 H289 L292 I296 V309 Y313	S51-M55 WeakPolarHBondContact O-CB 3.45Å; S51-M55 PolarHBondContact O-N 3.23Å; F52-M55 WeakPolarHBondContact O-CB 3.39Å; F52-M55 PolarHBondContact O-N 3.47Å; F52-M55 VanDerWaalsContact O-N 3.1Å; L53-M55 VanDerWaalsContact C-N 3.32Å; L53-M55 PolarHBondContact O-N 2.86Å; M55-F57 PolarHBondContact O-N 3.43Å; M55-V58 PolarHBondContact O-N 3.27Å; M55-V59 HydrophobicContact CE-CG2 3.4Å; M55-V59 VanDerWaalsContact CE-CG2 3.4Å; M55-V59 PolarHBondContact O-N 3.24Å; M55-V59 VanDerWaalsContact O-N 3.13Å; M55-V59 HydrophobicContact SD-CG2 3.8Å; M55-H289 WeakPolarHBondContact CA-NE2 3.43Å; M55-H289 PolarHBondContact N-NE2 3.42Å; M55-L292 HydrophobicContact CE-CD1 3.55Å; M55-L292 HydrophobicContact CE-CD2 3.76Å; M55-L292 HydrophobicContact CE-CG 4.18Å; M55-L292 HydrophobicContact CG-CD1 4.3Å; M55-L292 HydrophobicContact CG-CD2 4.01Å; M55-L292 HydrophobicContact SD-CD2 4.44Å; M55-I296 HydrophobicContact CE-CD1 3.83Å; M55-V309 HydrophobicContact CE-CB 3.98Å; M55-V309 HydrophobicContact CE-CG1 3.68Å; M55-V309 HydrophobicContact CE-CG2 3.37Å; M55-V309 HydrophobicContact CG-CG1 4.21Å; M55-V309 HydrophobicContact SD-CB 4.21Å; M55-V309 HydrophobicContact SD-CG1 3.59Å; M55-V309 VanDerWaalsContact SD-CG1 3.59Å; M55-V309 HydrophobicContact SD-CG2 4.24Å; M55-Y313 HydrophobicContact CB-CE2 4.42Å; M55-Y313 HydrophobicContact CG-CE2 4.42Å
56	T	94.7	Very high	93.2	Very high	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-61.8	-33.7	178	74.4	0	0	0	0	112.9	F52 L53 N54 V59 E60 Y306 S507 P508 F509	F52-T56 HydrophobicContact CD2-CG2 4.38Å; F52-T56 HydrophobicContact CE1-CG2 4.18Å; F52-T56 HydrophobicContact CE2-CG2 3.93Å; F52-T56 HydrophobicContact CZ-CG2 3.81Å; F52-T56 VanDerWaalsContact O-CG2 3.29Å; F52-T56 WeakPolarHBondContact O-CG2 3.28Å; F52-T56 PolarHBondContact O-N 3.49Å; L53-T56 PolarHBondContact O-N 2.83Å; L53-T56 PolarHBondContact O-OG1 3.04Å; N54-T56 VanDerWaalsContact C-N 3.26Å; N54-T56 PolarHBondContact O-N 2.72Å; T56-V59 PolarHBondContact O-N 3.43Å; T56-E60 PolarHBondContact O-N 3.47Å; T56-Y306 HydrophobicContact CG2-CD1 3.66Å; T56-Y306 HydrophobicContact CG2-CE1 4.03Å; T56-S507 WeakPolarHBondContact CB-OG 3.18Å; T56-S507 PolarHBondContact OG1-OG 3.09Å; T56-P508 HydrophobicContact CG2-CG 4.45Å; T56-F509 HydrophobicContact CG2-CD2 4.4Å; T56-F509 HydrophobicContact CG2-CE2 4.31Å
57	F	95.1	Very high	92.6	Very high	0 Å²	0	6.4 Å²	6.4	0%	0	3%	0.033	C	C	.	.	H	α-helix	trans	-65.5	-39.6	173.9	-64.8	-18.1	0	0	0	112.1	L53 N54 M55 E60 V61 P483 A487 F509 W514 L515	L53-F57 HydrophobicContact CD2-CD2 4.04Å; L53-F57 HydrophobicContact CD2-CE1 4.37Å; L53-F57 HydrophobicContact CD2-CE2 3.24Å; L53-F57 HydrophobicContact CD2-CZ 3.45Å; L53-F57 VanDerWaalsContact CD2-CZ 3.45Å; L53-F57 HydrophobicContact CG-CE2 4.34Å; L53-F57 HydrophobicContact CG-CZ 4.12Å; L53-F57 PolarHBondContact O-N 2.88Å; N54-F57 WeakPolarHBondContact O-CB 3.19Å; N54-F57 PolarHBondContact O-N 2.97Å; M55-F57 PolarHBondContact O-N 3.43Å; F57-E60 PolarHBondContact O-N 3.31Å; F57-V61 WeakPolarHBondContact O-CB 3.48Å; F57-V61 WeakPolarHBondContact O-CG2 3.38Å; F57-V61 PolarHBondContact O-N 2.98Å; F57-P483 HydrophobicContact CB-CB 4.32Å; F57-A487 HydrophobicContact CB-CB 3.83Å; F57-A487 HydrophobicContact CD1-CB 4.29Å; F57-A487 HydrophobicContact CD2-CB 4.37Å; F57-A487 HydrophobicContact CG-CB 3.93Å; F57-F509 HydrophobicContact CE1-CB 3.97Å; F57-F509 HydrophobicContact CZ-CB 4.37Å; F57-W514 HydrophobicContact CZ-CB 4.07Å; F57-L515 HydrophobicContact CD2-CD2 3.94Å; F57-L515 HydrophobicContact CE1-CD2 4.23Å; F57-L515 HydrophobicContact CE2-CD2 3.52Å; F57-L515 HydrophobicContact CG-CD2 4.45Å; F57-L515 HydrophobicContact CZ-CD2 3.68Å; F57-L515 HydrophobicContact CZ-CG 4.39Å
58	V	93.8	Very high	92	Very high	0 Å²	0	6.6 Å²	6.6	0%	0	4%	0.035	C	C	.	.	H	α-helix	trans	-62.9	-44.5	175.3	-178.2	0	0	0	0	110.8	N54 M55 E60 V61 L62 L128 H289 L292 P483	N54-V58 PolarHBondContact O-N 3.44Å; N54-V58 VanDerWaalsContact O-N 3.15Å; M55-V58 PolarHBondContact O-N 3.27Å; V58-E60 PolarHBondContact O-N 2.69Å; V58-V61 PolarHBondContact O-N 3.3Å; V58-L62 HydrophobicContact CG1-CD1 3.89Å; V58-L62 HydrophobicContact CG1-CG 4.18Å; V58-L62 WeakPolarHBondContact O-CB 3Å; V58-L62 VanDerWaalsContact O-CG 3.23Å; V58-L62 WeakPolarHBondContact O-CG 3.15Å; V58-L62 PolarHBondContact O-N 3.49Å; V58-L128 HydrophobicContact CG1-CD1 4.04Å; V58-H289 HydrophobicContact CG2-CB 4.22Å; V58-L292 HydrophobicContact CB-CD2 3.87Å; V58-L292 HydrophobicContact CG1-CD2 3.73Å; V58-P483 HydrophobicContact CG2-CB 3.73Å; V58-P483 HydrophobicContact CG2-CG 3.69Å
59	V	91.1	Very high	91.3	Very high	0 Å²	0	7 Å²	7	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-60.7	-44.7	177.6	-178	0	0	0	0	111.9	M55 T56 L62 S63 M122 L292 I296 I305 Y306	M55-V59 HydrophobicContact CE-CG2 3.4Å; M55-V59 VanDerWaalsContact CE-CG2 3.4Å; M55-V59 PolarHBondContact O-N 3.24Å; M55-V59 VanDerWaalsContact O-N 3.13Å; M55-V59 HydrophobicContact SD-CG2 3.8Å; T56-V59 PolarHBondContact O-N 3.43Å; V59-L62 PolarHBondContact O-N 3.24Å; V59-S63 PolarHBondContact O-N 2.93Å; V59-S63 PolarHBondContact O-OG 2.88Å; V59-M122 HydrophobicContact CG1-CE 4.16Å; V59-L292 HydrophobicContact CG2-CD2 3.84Å; V59-I296 HydrophobicContact CG2-CD1 3.48Å; V59-I296 VanDerWaalsContact CG2-CD1 3.48Å; V59-I305 HydrophobicContact CG1-CD1 4.37Å; V59-I305 HydrophobicContact CG1-CG2 4.17Å; V59-Y306 HydrophobicContact CB-CE1 3.86Å; V59-Y306 HydrophobicContact CG1-CE1 4.02Å; V59-Y306 HydrophobicContact CG2-CE1 4.32Å
60	E	92.2	Very high	90.5	Very high	0 Å²	0	6.8 Å²	6.8	0%	0	4%	0.036	C	C	.	.	H	α-helix	trans	-58.9	-47.8	176.7	176.6	-177.1	100.2	0	0	111.1	T56 F57 V58 L62 S63 A64 R491 Y498 Y505 S507	T56-E60 PolarHBondContact O-N 3.47Å; F57-E60 PolarHBondContact O-N 3.31Å; V58-E60 PolarHBondContact O-N 2.69Å; E60-L62 PolarHBondContact O-N 2.68Å; E60-S63 PolarHBondContact O-N 2.85Å; E60-A64 PolarHBondContact O-N 3.49Å; E60-R491 IonicContact OE1-CZ 2.76Å; E60-R491 IonicContact OE1-NE 3.51Å; E60-R491 PolarHBondContact OE1-NE 3.38Å; E60-R491 IonicContact OE1-NH2 2.78Å; E60-R491 PolarHBondContact OE1-NH2 3.2Å; E60-R491 IonicContact OE2-CZ 3.97Å; E60-R491 IonicContact OE2-NE 3.2Å; E60-R491 IonicContact OE2-NH2 3.29Å; E60-R491 PolarHBondContact OE2-NH2 2.9Å; E60-Y498 HydrophobicContact CG-CE2 4.12Å; E60-Y505 WeakPolarHBondContact CA-O 3.29Å; E60-S507 WeakPolarHBondContact OE2-CB 3.46Å; E60-S507 PolarHBondContact OE2-N 3.38Å
61	V	92	Very high	89.5	Confident	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-62.3	-44.8	178.5	166.2	0	0	0	0	111.8	F57 V58 S63 A64 V65 L135 L486 A487 V490	F57-V61 WeakPolarHBondContact O-CB 3.48Å; F57-V61 WeakPolarHBondContact O-CG2 3.38Å; F57-V61 PolarHBondContact O-N 2.98Å; V58-V61 PolarHBondContact O-N 3.3Å; V61-S63 VanDerWaalsContact C-N 3.27Å; V61-S63 PolarHBondContact O-N 2.9Å; V61-A64 PolarHBondContact O-N 2.88Å; V61-V65 HydrophobicContact CG1-CG2 4.25Å; V61-V65 WeakPolarHBondContact O-CB 3.13Å; V61-V65 VanDerWaalsContact O-CG2 3.32Å; V61-V65 WeakPolarHBondContact O-CG2 3.28Å; V61-V65 PolarHBondContact O-N 3.46Å; V61-L135 HydrophobicContact CG1-CD1 3.56Å; V61-L486 HydrophobicContact CB-CB 4.34Å; V61-L486 HydrophobicContact CG1-CB 3.96Å; V61-L486 HydrophobicContact CG1-CD1 4.21Å; V61-L486 HydrophobicContact CG1-CD2 4.43Å; V61-L486 HydrophobicContact CG1-CG 4.43Å; V61-L486 HydrophobicContact CG2-CB 3.59Å; V61-A487 HydrophobicContact CG2-CB 4.25Å; V61-V490 HydrophobicContact CG2-CG2 4.07Å
62	L	88.6	Confident	88.5	Confident	4 Å²	4	11.7 Å²	11.7	2%	0.021	6%	0.058	C	C	.	.	H	α-helix	trans	-63.8	-36	179.6	-69.5	171.5	0	0	0	111.8	V58 V59 E60 G66 M122 A131 P293	V58-L62 HydrophobicContact CG1-CD1 3.89Å; V58-L62 HydrophobicContact CG1-CG 4.18Å; V58-L62 WeakPolarHBondContact O-CB 3Å; V58-L62 VanDerWaalsContact O-CG 3.23Å; V58-L62 WeakPolarHBondContact O-CG 3.15Å; V58-L62 PolarHBondContact O-N 3.49Å; V59-L62 PolarHBondContact O-N 3.24Å; E60-L62 PolarHBondContact O-N 2.68Å; L62-G66 PolarHBondContact O-N 3.3Å; L62-M122 HydrophobicContact CB-CG 4.29Å; L62-M122 HydrophobicContact CB-SD 3.44Å; L62-M122 WeakPolarHBondContact CB-SD 3.23Å; L62-M122 HydrophobicContact CD1-SD 4.32Å; L62-A131 HydrophobicContact CD2-CB 4.47Å; L62-P293 HydrophobicContact CD1-CB 4.06Å; L62-P293 HydrophobicContact CD1-CG 3.8Å; L62-P293 HydrophobicContact CD2-CB 4.31Å; L62-P293 HydrophobicContact CD2-CG 3.98Å
63	S	87.7	Confident	87.5	Confident	0 Å²	0	15 Å²	15	0%	0	7%	0.07	C	C	.	.	H	α-helix	trans	-68.2	-43.7	176	-50	0	0	0	0	111	V59 E60 V61 G66 A67 Y505	V59-S63 PolarHBondContact O-N 2.93Å; V59-S63 PolarHBondContact O-OG 2.88Å; E60-S63 PolarHBondContact O-N 2.85Å; V61-S63 VanDerWaalsContact C-N 3.27Å; V61-S63 PolarHBondContact O-N 2.9Å; S63-G66 PolarHBondContact O-N 3.31Å; S63-A67 PolarHBondContact O-N 3.39Å; S63-Y505 WeakPolarHBondContact OG-CD1 3.05Å
64	A	88.7	Confident	86.5	Confident	3 Å²	3	18.3 Å²	18.3	3%	0.025	9%	0.09	C	C	.	.	H	α-helix	trans	-63.2	-46.2	176.1	0	0	0	0	0	112.4	E60 V61 A67 S68 V490 L497 M501	E60-A64 PolarHBondContact O-N 3.49Å; V61-A64 PolarHBondContact O-N 2.88Å; A64-A67 PolarHBondContact O-N 2.84Å; A64-S68 PolarHBondContact O-N 2.77Å; A64-V490 HydrophobicContact CB-CG1 3.59Å; A64-V490 HydrophobicContact CB-CG2 4.23Å; A64-L497 WeakPolarHBondContact O-CD2 3.38Å; A64-M501 HydrophobicContact CB-CE 3.61Å
65	V	87.3	Confident	85.2	Confident	1 Å²	1	23.6 Å²	23.6	1%	0.006	11%	0.114	C	C	.	.	H	α-helix	trans	-69.6	-35.4	179.3	177	0	0	0	0	111.2	V61 A67 S68 V69 I126 A131 I134 L135	V61-V65 HydrophobicContact CG1-CG2 4.25Å; V61-V65 WeakPolarHBondContact O-CB 3.13Å; V61-V65 VanDerWaalsContact O-CG2 3.32Å; V61-V65 WeakPolarHBondContact O-CG2 3.28Å; V61-V65 PolarHBondContact O-N 3.46Å; V65-A67 VanDerWaalsContact C-N 3.34Å; V65-S68 PolarHBondContact O-N 2.87Å; V65-S68 PolarHBondContact O-OG 2.98Å; V65-S68 VanDerWaalsContact O-OG 3.05Å; V65-V69 HydrophobicContact CG1-CG2 4.31Å; V65-V69 WeakPolarHBondContact O-CB 3.47Å; V65-V69 VanDerWaalsContact O-CG2 3.3Å; V65-V69 WeakPolarHBondContact O-CG2 3.48Å; V65-V69 PolarHBondContact O-N 2.76Å; V65-I126 HydrophobicContact CG1-CD1 4.03Å; V65-I126 HydrophobicContact CG1-CG2 4.08Å; V65-A131 HydrophobicContact CB-CB 4.43Å; V65-A131 HydrophobicContact CG1-CB 4.21Å; V65-A131 HydrophobicContact CG2-CB 4.15Å; V65-I134 HydrophobicContact CG1-CD1 3.75Å; V65-L135 HydrophobicContact CG2-CD1 3.48Å; V65-L135 VanDerWaalsContact CG2-CD1 3.48Å; V65-L135 HydrophobicContact CG2-CD2 4.13Å; V65-L135 HydrophobicContact CG2-CG 3.78Å
66	G	85.4	Confident	83.9	Confident	13 Å²	13	24.3 Å²	24.3	13%	0.134	12%	0.119	C	C	.	.	H	α-helix	trans	-56.3	-49.1	171.6	0	0	0	0	0	112.1	L62 S63 V69 K70	L62-G66 PolarHBondContact O-N 3.3Å; S63-G66 PolarHBondContact O-N 3.31Å; G66-V69 PolarHBondContact O-N 3.09Å; G66-K70 WeakPolarHBondContact O-CB 3.37Å; G66-K70 PolarHBondContact O-N 3.36Å
67	A	83.5	Confident	82.6	Confident	0 Å²	0	29.8 Å²	29.8	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-63.6	-44.7	176.7	0	0	0	0	0	112.4	S63 A64 V65 V69 K70 M71 F119 F120 L497	S63-A67 PolarHBondContact O-N 3.39Å; A64-A67 PolarHBondContact O-N 2.84Å; V65-A67 VanDerWaalsContact C-N 3.34Å; A67-V69 VanDerWaalsContact C-N 3.34Å; A67-V69 PolarHBondContact O-N 3.14Å; A67-K70 PolarHBondContact O-N 2.74Å; A67-M71 WeakPolarHBondContact O-CB 3.39Å; A67-M71 PolarHBondContact O-N 2.8Å; A67-F119 WeakPolarHBondContact CA-O 3.37Å; A67-F119 HydrophobicContact CB-CD1 3.77Å; A67-F119 HydrophobicContact CB-CE1 3.93Å; A67-F119 VanDerWaalsContact O-CE1 3.24Å; A67-F119 WeakPolarHBondContact O-CE1 3.06Å; A67-F120 HydrophobicContact CB-CD1 3.51Å; A67-F120 HydrophobicContact CB-CE1 3.74Å; A67-F120 HydrophobicContact CB-CG 4.23Å; A67-L497 HydrophobicContact CB-CD1 4.01Å; A67-L497 HydrophobicContact CB-CD2 4.5Å
68	S	82.9	Confident	81	Confident	4 Å²	4	35.7 Å²	35.7	3%	0.028	18%	0.179	C	C	.	.	H	α-helix	trans	-63.2	-39.5	-179.9	74.3	0	0	0	0	112.4	A64 V65 M71 K72	A64-S68 PolarHBondContact O-N 2.77Å; V65-S68 PolarHBondContact O-N 2.87Å; V65-S68 PolarHBondContact O-OG 2.98Å; V65-S68 VanDerWaalsContact O-OG 3.05Å; S68-M71 PolarHBondContact O-N 3.24Å; S68-K72 WeakPolarHBondContact O-CG 3.38Å; S68-K72 PolarHBondContact O-N 2.94Å; S68-K72 VanDerWaalsContact O-N 3.07Å
69	V	80.7	Confident	79.2	Confident	17 Å²	17	38.6 Å²	38.6	10%	0.103	20%	0.203	C	C	.	.	H	α-helix	trans	-67.2	-40.5	175.6	172.5	0	0	0	0	111.5	V65 G66 A67 M71 K72 R73 I126 I134	V65-V69 HydrophobicContact CG1-CG2 4.31Å; V65-V69 WeakPolarHBondContact O-CB 3.47Å; V65-V69 VanDerWaalsContact O-CG2 3.3Å; V65-V69 WeakPolarHBondContact O-CG2 3.48Å; V65-V69 PolarHBondContact O-N 2.76Å; G66-V69 PolarHBondContact O-N 3.09Å; A67-V69 VanDerWaalsContact C-N 3.34Å; A67-V69 PolarHBondContact O-N 3.14Å; V69-M71 VanDerWaalsContact C-N 3.34Å; V69-K72 PolarHBondContact O-N 2.75Å; V69-R73 PolarHBondContact O-N 3.11Å; V69-R73 VanDerWaalsContact O-N 3.16Å; V69-I126 HydrophobicContact CB-CD1 4.43Å; V69-I126 HydrophobicContact CG2-CD1 4.19Å; V69-I134 HydrophobicContact CG2-CD1 3.98Å
70	K	80.5	Confident	77	Confident	72 Å²	72	43.4 Å²	43.4	31%	0.313	24%	0.237	S	C	.	.	H	α-helix	trans	-63.1	-41.4	176.3	-165.3	176.9	-177.2	-176.3	0	111.2	G66 A67 R73 V74 D118 F119	G66-K70 WeakPolarHBondContact O-CB 3.37Å; G66-K70 PolarHBondContact O-N 3.36Å; A67-K70 PolarHBondContact O-N 2.74Å; K70-R73 WeakPolarHBondContact O-CB 3.41Å; K70-R73 PolarHBondContact O-N 2.87Å; K70-V74 PolarHBondContact O-N 2.88Å; K70-V74 VanDerWaalsContact O-N 3.15Å; K70-D118 PolarHBondContact NZ-O 3.11Å; K70-F119 HydrophobicContact CB-CE2 4.19Å; K70-F119 HydrophobicContact CB-CZ 4.15Å; K70-F119 HydrophobicContact CD-CD2 3.7Å; K70-F119 HydrophobicContact CD-CE2 3.93Å; K70-F119 HydrophobicContact CD-CG 4.19Å; K70-F119 HydrophobicContact CG-CD2 4.19Å; K70-F119 HydrophobicContact CG-CE2 3.88Å; K70-F119 HydrophobicContact CG-CZ 4.35Å
71	M	75.3	Confident	74.6	Confident	29 Å²	29	49.2 Å²	49.2	14%	0.143	28%	0.275	C	S	.	.	H	α-helix	trans	-60.8	-46.7	176	-163.9	172	-176.8	0	0	112.5	A67 S68 V69 R73 V74 H75 I97 H100 F119	A67-M71 WeakPolarHBondContact O-CB 3.39Å; A67-M71 PolarHBondContact O-N 2.8Å; S68-M71 PolarHBondContact O-N 3.24Å; V69-M71 VanDerWaalsContact C-N 3.34Å; M71-R73 PolarHBondContact O-N 3.39Å; M71-V74 PolarHBondContact O-N 3.44Å; M71-H75 PolarHBondContact O-N 2.96Å; M71-H75 VanDerWaalsContact O-N 3.1Å; M71-I97 HydrophobicContact CE-CB 4.31Å; M71-I97 HydrophobicContact CE-CG1 4.28Å; M71-I97 HydrophobicContact CE-CG2 4.3Å; M71-I97 HydrophobicContact SD-CB 4.3Å; M71-I97 HydrophobicContact SD-CG1 3.86Å; M71-I97 HydrophobicContact SD-CG2 4.03Å; M71-H100 HydrophobicContact CE-CB 3.4Å; M71-H100 VanDerWaalsContact CE-CB 3.4Å; M71-F119 HydrophobicContact CB-CE1 4.13Å; M71-F119 HydrophobicContact CB-CZ 3.68Å; M71-F119 HydrophobicContact CG-CZ 4.25Å
72	K	76.5	Confident	72.3	Confident	74 Å²	74	57.1 Å²	57.1	32%	0.322	32%	0.315	S	S	.	.	H	α-helix	trans	-58	-37.3	176.1	-74.1	-175.4	-179.8	-164.3	0	112	S68 V69 S76 E93	S68-K72 WeakPolarHBondContact O-CG 3.38Å; S68-K72 PolarHBondContact O-N 2.94Å; S68-K72 VanDerWaalsContact O-N 3.07Å; V69-K72 PolarHBondContact O-N 2.75Å; K72-S76 WeakPolarHBondContact O-CB 3.07Å; K72-S76 PolarHBondContact O-N 3.37Å; K72-S76 VanDerWaalsContact O-N 3.08Å; K72-S76 PolarHBondContact O-OG 3.37Å; K72-E93 WeakPolarHBondContact CE-OE1 3.24Å; K72-E93 IonicContact NZ-OE1 3.11Å; K72-E93 PolarHBondContact NZ-OE1 2.95Å; K72-E93 IonicContact NZ-OE2 2.65Å; K72-E93 PolarHBondContact NZ-OE2 2.85Å
73	R	73.9	Confident	69.7	Low	99 Å²	99	63.9 Å²	63.9	37%	0.374	35%	0.352	S	S	.	.	H	α-helix	trans	-67.5	-45.3	179.1	-171.7	176.9	-64.6	156.2	5.7	112.2	V69 K70 M71 S76 L77 E124 Y404	V69-R73 PolarHBondContact O-N 3.11Å; V69-R73 VanDerWaalsContact O-N 3.16Å; K70-R73 WeakPolarHBondContact O-CB 3.41Å; K70-R73 PolarHBondContact O-N 2.87Å; M71-R73 PolarHBondContact O-N 3.39Å; R73-S76 WeakPolarHBondContact CA-OG 3.37Å; R73-S76 PolarHBondContact O-N 3.41Å; R73-S76 PolarHBondContact O-OG 3.49Å; R73-L77 HydrophobicContact CG-CD1 4.27Å; R73-L77 WeakPolarHBondContact O-CG 3.39Å; R73-L77 PolarHBondContact O-N 3.01Å; R73-L77 VanDerWaalsContact O-N 3.12Å; R73-E124 IonicContact CZ-OE1 2.78Å; R73-E124 IonicContact CZ-OE2 2.86Å; R73-E124 IonicContact NH1-OE1 3.02Å; R73-E124 PolarHBondContact NH1-OE1 2.91Å; R73-E124 IonicContact NH2-OE1 3.12Å; R73-E124 PolarHBondContact NH2-OE1 3.18Å; R73-E124 IonicContact NH2-OE2 2.74Å; R73-E124 PolarHBondContact NH2-OE2 3.29Å; R73-Y404 HydrophobicContact CG-CE1 4.48Å
74	V	75.9	Confident	67.2	Low	68 Å²	68	69.4 Å²	69.4	41%	0.412	39%	0.385	S	S	.	.	H	α-helix	trans	-59.9	-50	177.8	176.3	0	0	0	0	109.9	K70 M71 S76 L77 D78	K70-V74 PolarHBondContact O-N 2.88Å; K70-V74 VanDerWaalsContact O-N 3.15Å; M71-V74 PolarHBondContact O-N 3.44Å; V74-S76 VanDerWaalsContact C-N 3.27Å; V74-S76 PolarHBondContact O-N 3.06Å; V74-L77 WeakPolarHBondContact O-CB 3.3Å; V74-L77 PolarHBondContact O-N 2.84Å; V74-D78 PolarHBondContact O-N 3.1Å; V74-D78 VanDerWaalsContact O-N 3.08Å
75	H	68.4	Low	64.7	Low	112 Å²	112	74.7 Å²	74.7	52%	0.519	42%	0.419	S	S	.	.	H	α-helix	trans	-56.9	-39.8	177.2	-177.1	-85.6	0	0	0	113	M71 L77 D78 A79	M71-H75 PolarHBondContact O-N 2.96Å; M71-H75 VanDerWaalsContact O-N 3.1Å; H75-L77 VanDerWaalsContact C-N 3.29Å; H75-L77 PolarHBondContact O-N 3.18Å; H75-D78 PolarHBondContact O-N 3.23Å; H75-A79 VanDerWaalsContact O-CB 3.25Å; H75-A79 WeakPolarHBondContact O-CB 3.41Å; H75-A79 PolarHBondContact O-N 3.4Å
76	S	67.4	Low	62.4	Low	15 Å²	15	79.7 Å²	79.7	11%	0.105	45%	0.45	C	S	.	.	H	α-helix	trans	-74.9	-14.7	179	57.2	0	0	0	0	114.9	K72 R73 V74 Y404	K72-S76 WeakPolarHBondContact O-CB 3.07Å; K72-S76 PolarHBondContact O-N 3.37Å; K72-S76 VanDerWaalsContact O-N 3.08Å; K72-S76 PolarHBondContact O-OG 3.37Å; R73-S76 WeakPolarHBondContact CA-OG 3.37Å; R73-S76 PolarHBondContact O-N 3.41Å; R73-S76 PolarHBondContact O-OG 3.49Å; V74-S76 VanDerWaalsContact C-N 3.27Å; V74-S76 PolarHBondContact O-N 3.06Å; S76-Y404 WeakPolarHBondContact CB-OH 3.19Å; S76-Y404 PolarHBondContact OG-OH 3.1Å
77	L	67.9	Low	60.2	Low	114 Å²	114	87.1 Å²	87.1	60%	0.597	48%	0.481	S	S	*	.	H	α-helix	trans	-85.4	-36.5	171.5	-70.5	167.6	0	0	0	110.9	R73 V74 H75	R73-L77 HydrophobicContact CG-CD1 4.27Å; R73-L77 WeakPolarHBondContact O-CG 3.39Å; R73-L77 PolarHBondContact O-N 3.01Å; R73-L77 VanDerWaalsContact O-N 3.12Å; V74-L77 WeakPolarHBondContact O-CB 3.3Å; V74-L77 PolarHBondContact O-N 2.84Å; H75-L77 VanDerWaalsContact C-N 3.29Å; H75-L77 PolarHBondContact O-N 3.18Å
78	D	61.4	Low	58.2	Low	125 Å²	125	90.3 Å²	90.3	67%	0.668	50%	0.497	S	S	*	.	H	α-helix	trans	-75.5	-26.2	177	-61	-30.6	0	0	0	112.2	V74 H75 S80	V74-D78 PolarHBondContact O-N 3.1Å; V74-D78 VanDerWaalsContact O-N 3.08Å; H75-D78 PolarHBondContact O-N 3.23Å; D78-S80 PolarHBondContact O-N 3.24Å
79	A	56.9	Low	56.4	Low	61 Å²	61	96.6 Å²	96.6	50%	0.504	53%	0.527	S	S	.	.			trans	-84.7	83.6	174.9	0	0	0	0	0	112.6	H75	H75-A79 VanDerWaalsContact O-CB 3.25Å; H75-A79 WeakPolarHBondContact O-CB 3.41Å; H75-A79 PolarHBondContact O-N 3.4Å
80	S	44.7	Very low	54.9	Low	100 Å²	100	101 Å²	101	70%	0.699	55%	0.549	S	S	*	.			trans	-140.6	144.7	163.8	-85	0	0	0	0	111.4	D78	D78-S80 PolarHBondContact O-N 3.24Å
81	P	41.8	Very low	53.5	Low	123 Å²	123	104 Å²	104	80%	0.799	57%	0.569	S	S	*	*	S	Bend		-111.5	105.6	-53.3	32.9	-16.5	0	0	0	109.4
82	I	43.1	Very low	52.2	Low	166 Å²	166	107.6 Å²	107.6	85%	0.851	59%	0.585	S	S	*	*	S	Bend	trans	-123.5	102.1	156.6	-61.2	179.8	0	0	0	106.4
83	N	33.3	Very low	51.1	Low	146 Å²	146	105.6 Å²	105.6	78%	0.781	58%	0.577	S	S	*	*	S	Bend	trans	22.7	130	158.9	-61.7	-26.7	0	0	0	118.8
84	T	36.4	Very low	50.2	Low	115 Å²	115	103 Å²	103	71%	0.706	57%	0.569	S	S	*	*			trans	100.2	110.5	160.8	-21.6	0	0	0	0	114.5	T86	T84-T86 PolarHBondContact O-N 3Å
85	P	36.6	Very low	49.1	Very low	114 Å²	114	102.6 Å²	102.6	74%	0.74	57%	0.569	S	S	*	*			trans	-71	96.6	166.9	29.7	-29.1	0	0	0	107.7	H87	P85-H87 PolarHBondContact O-N 2.98Å
86	T	39	Very low	48.5	Very low	106 Å²	106	100 Å²	100	65%	0.65	56%	0.561	S	S	*	*			trans	-68.8	114.2	172.1	12.3	0	0	0	0	108.8	T84 L88	T84-T86 PolarHBondContact O-N 3Å; T86-L88 PolarHBondContact O-N 3.05Å
87	H	37.6	Very low	48.2	Very low	169 Å²	169	100.1 Å²	100.1	78%	0.782	56%	0.56	S	S	*	*			trans	-70.9	81.3	168.5	-166.9	-75.3	0	0	0	107.4	P85 E89	P85-H87 PolarHBondContact O-N 2.98Å; H87-E89 PolarHBondContact O-N 3.36Å; H87-E89 VanDerWaalsContact O-N 3.08Å
88	L	43.1	Very low	47.8	Very low	67 Å²	67	102.2 Å²	102.2	35%	0.351	56%	0.56	S	S	.	*			trans	-65.3	110.4	176.1	-66.1	161.6	0	0	0	107.1	T86 E92	T86-L88 PolarHBondContact O-N 3.05Å; L88-E92 HydrophobicContact CB-CB 4.15Å; L88-E92 HydrophobicContact CD2-CB 3.62Å; L88-E92 HydrophobicContact CD2-CG 4.44Å; L88-E92 WeakPolarHBondContact CD2-OE2 3.39Å; L88-E92 HydrophobicContact CG-CB 4.49Å
89	E	43.2	Very low	47.7	Very low	137 Å²	137	102.2 Å²	102.2	64%	0.64	55%	0.554	S	S	*	*			trans	-59.9	154.5	168.5	-64.4	-174.9	149.9	0	0	109.1	H87 D91 E92 E93	H87-E89 PolarHBondContact O-N 3.36Å; H87-E89 VanDerWaalsContact O-N 3.08Å; E89-D91 PolarHBondContact O-N 2.99Å; E89-E92 PolarHBondContact O-N 3.01Å; E89-E93 PolarHBondContact O-N 3.23Å
90	D	49.4	Very low	47.9	Very low	109 Å²	109	104.3 Å²	104.3	58%	0.583	55%	0.553	S	S	*	*	H	α-helix	trans	-44.2	-38	-175.9	-79.9	-17.7	0	0	0	112.3	E93 H94	D90-E93 PolarHBondContact O-N 3.48Å; D90-H94 PolarHBondContact O-CE1 3.31Å; D90-H94 PolarHBondContact O-N 3.07Å; D90-H94 PolarHBondContact O-ND1 3.01Å
91	D	50.8	Low	48.5	Very low	135 Å²	135	100.4 Å²	100.4	72%	0.722	53%	0.525	S	S	*	.	H	α-helix	trans	-70.5	-32.4	-179.6	-69.5	-28.3	0	0	0	114.5	E89 C95	E89-D91 PolarHBondContact O-N 2.99Å; D91-C95 PolarHBondContact O-N 2.91Å
92	E	49.3	Very low	49.2	Very low	105 Å²	105	97.7 Å²	97.7	49%	0.491	50%	0.503	S	S	.	.	H	α-helix	trans	-76.1	-30.3	174.2	-72.2	-169.9	136.5	0	0	112.1	L88 E89 C95 T96	L88-E92 HydrophobicContact CB-CB 4.15Å; L88-E92 HydrophobicContact CD2-CB 3.62Å; L88-E92 HydrophobicContact CD2-CG 4.44Å; L88-E92 WeakPolarHBondContact CD2-OE2 3.39Å; L88-E92 HydrophobicContact CG-CB 4.49Å; E89-E92 PolarHBondContact O-N 3.01Å; E92-C95 PolarHBondContact O-N 3.34Å; E92-T96 PolarHBondContact O-N 3.05Å; E92-T96 PolarHBondContact O-OG1 3.36Å
93	E	52.2	Low	49.7	Very low	31 Å²	31	93.8 Å²	93.8	15%	0.145	48%	0.483	C	S	.	.	H	α-helix	trans	-63.4	-42.9	173.4	-167.2	-178.4	142.4	0	0	111.2	K72 E89 D90 C95 T96 I97	K72-E93 WeakPolarHBondContact CE-OE1 3.24Å; K72-E93 IonicContact NZ-OE1 3.11Å; K72-E93 PolarHBondContact NZ-OE1 2.95Å; K72-E93 IonicContact NZ-OE2 2.65Å; K72-E93 PolarHBondContact NZ-OE2 2.85Å; E89-E93 PolarHBondContact O-N 3.23Å; D90-E93 PolarHBondContact O-N 3.48Å; E93-C95 VanDerWaalsContact C-N 3.32Å; E93-C95 PolarHBondContact O-N 3.31Å; E93-T96 WeakPolarHBondContact CA-OG1 3.24Å; E93-T96 PolarHBondContact O-N 3.42Å; E93-T96 PolarHBondContact O-OG1 3.48Å; E93-I97 HydrophobicContact CG-CD1 4.25Å; E93-I97 WeakPolarHBondContact O-CG1 3.33Å; E93-I97 PolarHBondContact O-N 3.19Å; E93-I97 VanDerWaalsContact O-N 3.07Å
94	H	56.5	Low	50.5	Low	45 Å²	45	89.6 Å²	89.6	21%	0.208	47%	0.465	C	S	.	.	H	α-helix	trans	-64.4	-37.3	174.7	-65.7	106.9	0	0	0	112.1	D90 R98 S493 Y494	D90-H94 PolarHBondContact O-CE1 3.31Å; D90-H94 PolarHBondContact O-N 3.07Å; D90-H94 PolarHBondContact O-ND1 3.01Å; H94-R98 VanDerWaalsContact O-CB 3.24Å; H94-R98 WeakPolarHBondContact O-CB 3.36Å; H94-R98 PolarHBondContact O-N 3.43Å; H94-S493 PolarHBondContact CD2-O 3.24Å; H94-S493 PolarHBondContact NE2-O 3.05Å; H94-Y494 AromaticContact NE2-CE2 3.9Å; H94-Y494 AromaticContact NE2-CZ 3.99Å
95	C	53	Low	50.9	Low	60 Å²	60	88.2 Å²	88.2	41%	0.405	45%	0.454	S	S	.	.	H	α-helix	trans	-68.6	-38.9	179.3	-166.4	0	0	0	0	112	D91 E92 E93 R98 K99	D91-C95 PolarHBondContact O-N 2.91Å; E92-C95 PolarHBondContact O-N 3.34Å; E93-C95 VanDerWaalsContact C-N 3.32Å; E93-C95 PolarHBondContact O-N 3.31Å; C95-R98 PolarHBondContact O-N 3.1Å; C95-K99 WeakPolarHBondContact O-CB 3.36Å; C95-K99 WeakPolarHBondContact O-CG 3.41Å; C95-K99 PolarHBondContact O-N 3.35Å
96	T	55.7	Low	51.5	Low	58 Å²	58	89.3 Å²	89.3	36%	0.356	45%	0.453	S	S	.	.	H	α-helix	trans	-68.8	-43.2	176.2	42	0	0	0	0	112.2	E92 E93 R98 K99 H100	E92-T96 PolarHBondContact O-N 3.05Å; E92-T96 PolarHBondContact O-OG1 3.36Å; E93-T96 WeakPolarHBondContact CA-OG1 3.24Å; E93-T96 PolarHBondContact O-N 3.42Å; E93-T96 PolarHBondContact O-OG1 3.48Å; T96-R98 VanDerWaalsContact C-N 3.33Å; T96-R98 PolarHBondContact O-N 3.49Å; T96-K99 PolarHBondContact O-N 3Å; T96-H100 PolarHBondContact O-N 2.65Å
97	I	59.5	Low	51.9	Low	17 Å²	17	91.9 Å²	91.9	9%	0.087	46%	0.458	C	S	.	.	H	α-helix	trans	-59.1	-47.3	173.2	-67.9	163	0	0	0	110.5	M71 E93 H100 I101 Y494	M71-I97 HydrophobicContact CE-CB 4.31Å; M71-I97 HydrophobicContact CE-CG1 4.28Å; M71-I97 HydrophobicContact CE-CG2 4.3Å; M71-I97 HydrophobicContact SD-CB 4.3Å; M71-I97 HydrophobicContact SD-CG1 3.86Å; M71-I97 HydrophobicContact SD-CG2 4.03Å; E93-I97 HydrophobicContact CG-CD1 4.25Å; E93-I97 WeakPolarHBondContact O-CG1 3.33Å; E93-I97 PolarHBondContact O-N 3.19Å; E93-I97 VanDerWaalsContact O-N 3.07Å; I97-H100 PolarHBondContact O-N 2.98Å; I97-I101 HydrophobicContact CG2-CD1 3.88Å; I97-I101 WeakPolarHBondContact O-CG1 3.45Å; I97-I101 PolarHBondContact O-N 3.37Å; I97-I101 VanDerWaalsContact O-N 3.1Å; I97-Y494 HydrophobicContact CD1-CD1 4.5Å; I97-Y494 HydrophobicContact CD1-CE1 4.39Å
98	R	61.2	Low	51.8	Low	157 Å²	157	91.4 Å²	91.4	59%	0.592	46%	0.456	S	S	*	.	H	α-helix	trans	-61.8	-49.7	179.4	-174.2	175.6	-158.4	177.3	6.7	112.2	H94 C95 T96 H100 I101 D102	H94-R98 VanDerWaalsContact O-CB 3.24Å; H94-R98 WeakPolarHBondContact O-CB 3.36Å; H94-R98 PolarHBondContact O-N 3.43Å; C95-R98 PolarHBondContact O-N 3.1Å; T96-R98 VanDerWaalsContact C-N 3.33Å; T96-R98 PolarHBondContact O-N 3.49Å; R98-H100 PolarHBondContact O-N 3.08Å; R98-I101 PolarHBondContact O-N 3.31Å; R98-D102 WeakPolarHBondContact CG-OD2 3.29Å; R98-D102 WeakPolarHBondContact O-CB 3.37Å; R98-D102 VanDerWaalsContact O-CG 3.25Å; R98-D102 PolarHBondContact O-N 3.49Å
99	K	59.3	Low	51.6	Low	126 Å²	126	92.7 Å²	92.7	55%	0.548	49%	0.486	S	S	.	.	H	α-helix	trans	-56.2	-38.2	176.1	-81	-178.9	-178	178.5	0	111.7	C95 T96 D102 I103	C95-K99 WeakPolarHBondContact O-CB 3.36Å; C95-K99 WeakPolarHBondContact O-CG 3.41Å; C95-K99 PolarHBondContact O-N 3.35Å; T96-K99 PolarHBondContact O-N 3Å; K99-D102 PolarHBondContact O-N 3.35Å; K99-I103 HydrophobicContact CB-CD1 4.35Å; K99-I103 VanDerWaalsContact O-CB 3.23Å; K99-I103 WeakPolarHBondContact O-CB 3.42Å; K99-I103 WeakPolarHBondContact O-CD1 3.26Å; K99-I103 WeakPolarHBondContact O-CG1 3.33Å; K99-I103 PolarHBondContact O-N 3.48Å
100	H	59.1	Low	50.9	Low	105 Å²	105	93.7 Å²	93.7	49%	0.486	49%	0.49	S	S	.	.	H	α-helix	trans	-71.7	-37.8	-178.9	-149.6	-41.7	0	0	0	112.6	M71 T96 I97 R98 D102 S104	M71-H100 HydrophobicContact CE-CB 3.4Å; M71-H100 VanDerWaalsContact CE-CB 3.4Å; T96-H100 PolarHBondContact O-N 2.65Å; I97-H100 PolarHBondContact O-N 2.98Å; R98-H100 PolarHBondContact O-N 3.08Å; H100-D102 VanDerWaalsContact C-N 3.34Å; H100-S104 WeakPolarHBondContact O-CB 3.36Å; H100-S104 PolarHBondContact O-N 3.41Å; H100-S104 PolarHBondContact O-OG 2.98Å
101	I	59.3	Low	50.1	Low	18 Å²	18	93.3 Å²	93.3	9%	0.092	50%	0.496	C	S	.	.	H	α-helix	trans	-65.5	-41.3	173.1	-66.6	167.9	0	0	0	109.8	I97 R98 S104 N105 L115 A496	I97-I101 HydrophobicContact CG2-CD1 3.88Å; I97-I101 WeakPolarHBondContact O-CG1 3.45Å; I97-I101 PolarHBondContact O-N 3.37Å; I97-I101 VanDerWaalsContact O-N 3.1Å; R98-I101 PolarHBondContact O-N 3.31Å; I101-S104 WeakPolarHBondContact CA-OG 3.46Å; I101-S104 PolarHBondContact O-OG 3.47Å; I101-N105 PolarHBondContact O-N 3.36Å; I101-N105 PolarHBondContact O-ND2 3.12Å; I101-L115 HydrophobicContact CG1-CD1 4.45Å; I101-A496 HydrophobicContact CD1-CB 3.71Å
102	D	55.2	Low	49.1	Very low	65 Å²	65	92 Å²	92	35%	0.348	50%	0.498	S	S	.	.	H	α-helix	trans	-70.5	-41.7	178.4	-66.1	-18.3	0	0	0	111.5	R98 K99 H100 S104 N105 D106	R98-D102 WeakPolarHBondContact CG-OD2 3.29Å; R98-D102 WeakPolarHBondContact O-CB 3.37Å; R98-D102 VanDerWaalsContact O-CG 3.25Å; R98-D102 PolarHBondContact O-N 3.49Å; K99-D102 PolarHBondContact O-N 3.35Å; H100-D102 VanDerWaalsContact C-N 3.34Å; D102-S104 PolarHBondContact O-N 3.44Å; D102-N105 CarbonylContact O-C 3.57Å; D102-N105 WeakPolarHBondContact O-CA 3.39Å; D102-N105 WeakPolarHBondContact O-CB 3.33Å; D102-N105 PolarHBondContact O-N 3.03Å; D102-D106 WeakPolarHBondContact O-CB 3.29Å; D102-D106 PolarHBondContact O-N 2.89Å
103	I	53.5	Low	48.6	Very low	85 Å²	85	94.8 Å²	94.8	44%	0.436	51%	0.511	S	S	.	.	H	α-helix	trans	-63.6	-40.9	175.6	-70.9	162.3	0	0	0	110.9	K99 N105 D106 E107	K99-I103 HydrophobicContact CB-CD1 4.35Å; K99-I103 VanDerWaalsContact O-CB 3.23Å; K99-I103 WeakPolarHBondContact O-CB 3.42Å; K99-I103 WeakPolarHBondContact O-CD1 3.26Å; K99-I103 WeakPolarHBondContact O-CG1 3.33Å; K99-I103 PolarHBondContact O-N 3.48Å; I103-N105 PolarHBondContact O-N 2.88Å; I103-D106 PolarHBondContact O-N 3.17Å; I103-E107 HydrophobicContact CG2-CG 4.21Å; I103-E107 PolarHBondContact O-N 2.98Å
104	S	49.6	Very low	48.6	Very low	58 Å²	58	96.7 Å²	96.7	41%	0.406	53%	0.532	S	S	.	.	H	α-helix	trans	-64.2	-19.8	172.3	52.3	0	0	0	0	113.2	H100 I101 D102	H100-S104 WeakPolarHBondContact O-CB 3.36Å; H100-S104 PolarHBondContact O-N 3.41Å; H100-S104 PolarHBondContact O-OG 2.98Å; I101-S104 WeakPolarHBondContact CA-OG 3.46Å; I101-S104 PolarHBondContact O-OG 3.47Å; D102-S104 PolarHBondContact O-N 3.44Å
105	N	46.2	Very low	48.7	Very low	86 Å²	86	96.7 Å²	96.7	46%	0.46	53%	0.533	S	S	.	.	H	α-helix	trans	-93.8	-25.4	176.6	-68.9	-29.2	0	0	0	113.4	I101 D102 I103	I101-N105 PolarHBondContact O-N 3.36Å; I101-N105 PolarHBondContact O-ND2 3.12Å; D102-N105 CarbonylContact O-C 3.57Å; D102-N105 WeakPolarHBondContact O-CA 3.39Å; D102-N105 WeakPolarHBondContact O-CB 3.33Å; D102-N105 PolarHBondContact O-N 3.03Å; I103-N105 PolarHBondContact O-N 2.88Å
106	D	48.2	Very low	48.9	Very low	137 Å²	137	98 Å²	98	73%	0.733	54%	0.541	S	S	*	.	H	α-helix	trans	-100.7	-21.3	-170.5	-74.1	-22.8	0	0	0	114.5	D102 I103	D102-D106 WeakPolarHBondContact O-CB 3.29Å; D102-D106 PolarHBondContact O-N 2.89Å; I103-D106 PolarHBondContact O-N 3.17Å
107	E	46.9	Very low	49.1	Very low	159 Å²	159	101 Å²	101	74%	0.743	55%	0.551	S	S	*	*	S	Bend	trans	-90.2	-8.6	-171.2	-73.9	-157.2	149.7	0	0	117.3	I103	I103-E107 HydrophobicContact CG2-CG 4.21Å; I103-E107 PolarHBondContact O-N 2.98Å
108	E	37.4	Very low	49	Very low	160 Å²	160	105.7 Å²	105.7	75%	0.748	58%	0.576	S	S	*	*			trans	-142.2	115.9	176.3	-72.9	-172.2	154.8	0	0	114.2	Q110	E108-Q110 PolarHBondContact O-N 2.87Å
109	G	38	Very low	48.8	Very low	94 Å²	94	99.3 Å²	99.3	97%	0.969	55%	0.553	S	S	*	*	S	Bend	trans	-68	34.3	169.6	0	0	0	0	0	114.8
110	Q	29	Very low	48.9	Very low	157 Å²	157	93.3 Å²	93.3	73%	0.734	53%	0.526	S	S	*	.	S	Bend	trans	-136.8	112.4	173	-78.4	179.1	5.5	0	0	108.5	E108	E108-Q110 PolarHBondContact O-N 2.87Å
111	S	31.7	Very low	48.8	Very low	102 Å²	102	89.7 Å²	89.7	71%	0.713	51%	0.511	S	S	*	.			trans	43.5	105.2	170.7	55.3	0	0	0	0	116.7	E113	S111-E113 PolarHBondContact O-N 2.97Å
112	S	31.1	Very low	48.8	Very low	108 Å²	108	89.1 Å²	89.1	76%	0.755	51%	0.508	S	S	*	.			trans	-37.5	94.1	166.1	-167.9	0	0	0	0	111.8	A114	S112-A114 PolarHBondContact O-N 2.96Å
113	E	38.6	Very low	48.8	Very low	162 Å²	162	89.9 Å²	89.9	76%	0.757	52%	0.515	S	S	*	.			trans	-78	81.5	171	-84.6	-163.6	157.3	0	0	106.3	S111 L115	S111-E113 PolarHBondContact O-N 2.97Å; E113-L115 PolarHBondContact O-N 3.1Å
114	A	51.7	Low	49	Very low	72 Å²	72	89 Å²	89	60%	0.595	51%	0.509	S	S	*	.			trans	-47.3	135.1	163.3	0	0	0	0	0	108.5	S112	S112-A114 PolarHBondContact O-N 2.96Å
115	L	58.2	Low	49.4	Very low	44 Å²	44	93.6 Å²	93.6	23%	0.23	52%	0.517	C	S	.	.			trans	-37	120.2	173.9	-86.2	162.7	0	0	0	108.8	I101 E113 E117 F119 F120 A500	I101-L115 HydrophobicContact CG1-CD1 4.45Å; E113-L115 PolarHBondContact O-N 3.1Å; L115-E117 PolarHBondContact O-N 3.2Å; L115-F119 HydrophobicContact CD2-CD1 4.1Å; L115-F119 HydrophobicContact CD2-CD2 4.5Å; L115-F119 HydrophobicContact CD2-CE1 4.27Å; L115-F119 HydrophobicContact CD2-CG 4.21Å; L115-F120 HydrophobicContact CB-CE2 3.77Å; L115-F120 HydrophobicContact CB-CZ 4.38Å; L115-F120 HydrophobicContact CD1-CE2 4.17Å; L115-F120 HydrophobicContact CD1-CZ 3.93Å; L115-A500 HydrophobicContact CD1-CB 3.89Å
116	P	58.3	Low	50.5	Low	87 Å²	87	89.9 Å²	89.9	57%	0.565	50%	0.497	S	S	*	.			trans	-48.4	135.6	-172.9	-29.8	33.4	0	0	0	110.4	D118 F119	P116-D118 PolarHBondContact O-N 3.1Å; P116-F119 WeakPolarHBondContact O-CA 3.47Å; P116-F119 WeakPolarHBondContact O-CB 3.41Å; P116-F119 PolarHBondContact O-N 3.02Å
117	E	59.1	Low	51.9	Low	121 Å²	121	89.8 Å²	89.8	57%	0.565	49%	0.493	S	S	*	.	G	3₁₀ helix	trans	-53.7	-31.8	-173.4	-65.6	-164.7	142.7	0	0	112.5	L115 F119 F120 P502 H504	L115-E117 PolarHBondContact O-N 3.2Å; E117-F119 PolarHBondContact O-N 2.67Å; E117-F119 VanDerWaalsContact O-N 3.11Å; E117-F120 PolarHBondContact O-N 3.18Å; E117-P502 HydrophobicContact CB-CG 4.39Å; E117-P502 HydrophobicContact CG-CG 4.1Å; E117-H504 IonicContact OE1-CE1 2.68Å; E117-H504 IonicContact OE1-ND1 3.63Å; E117-H504 IonicContact OE2-CE1 2.69Å
118	D	57.7	Low	53.7	Low	116 Å²	116	82.5 Å²	82.5	62%	0.62	46%	0.459	S	S	*	.	G	3₁₀ helix	trans	-62.1	-12.8	174.8	-64.8	-17.3	0	0	0	114.2	K70 P116	K70-D118 PolarHBondContact NZ-O 3.11Å; P116-D118 PolarHBondContact O-N 3.1Å
119	F	57.1	Low	55.9	Low	23 Å²	23	75 Å²	75	10%	0.101	42%	0.424	C	S	.	.	G	3₁₀ helix	trans	-73.3	-33	176.3	-160.1	-95	0	0	0	112.4	A67 K70 M71 L115 P116 E117	A67-F119 WeakPolarHBondContact CA-O 3.37Å; A67-F119 HydrophobicContact CB-CD1 3.77Å; A67-F119 HydrophobicContact CB-CE1 3.93Å; A67-F119 VanDerWaalsContact O-CE1 3.24Å; A67-F119 WeakPolarHBondContact O-CE1 3.06Å; K70-F119 HydrophobicContact CB-CE2 4.19Å; K70-F119 HydrophobicContact CB-CZ 4.15Å; K70-F119 HydrophobicContact CD-CD2 3.7Å; K70-F119 HydrophobicContact CD-CE2 3.93Å; K70-F119 HydrophobicContact CD-CG 4.19Å; K70-F119 HydrophobicContact CG-CD2 4.19Å; K70-F119 HydrophobicContact CG-CE2 3.88Å; K70-F119 HydrophobicContact CG-CZ 4.35Å; M71-F119 HydrophobicContact CB-CE1 4.13Å; M71-F119 HydrophobicContact CB-CZ 3.68Å; M71-F119 HydrophobicContact CG-CZ 4.25Å; L115-F119 HydrophobicContact CD2-CD1 4.1Å; L115-F119 HydrophobicContact CD2-CD2 4.5Å; L115-F119 HydrophobicContact CD2-CE1 4.27Å; L115-F119 HydrophobicContact CD2-CG 4.21Å; P116-F119 WeakPolarHBondContact O-CA 3.47Å; P116-F119 WeakPolarHBondContact O-CB 3.41Å; P116-F119 PolarHBondContact O-N 3.02Å; E117-F119 PolarHBondContact O-N 2.67Å; E117-F119 VanDerWaalsContact O-N 3.11Å
120	F	60.8	Low	58.1	Low	0 Å²	0	76.4 Å²	76.4	0%	0	40%	0.4	C	S	.	.	S	Bend	trans	-91.8	-5	175.9	-62	-86.8	0	0	0	112.5	A67 L115 E117 M122 L497 A500 M501 P502 Y505	A67-F120 HydrophobicContact CB-CD1 3.51Å; A67-F120 HydrophobicContact CB-CE1 3.74Å; A67-F120 HydrophobicContact CB-CG 4.23Å; L115-F120 HydrophobicContact CB-CE2 3.77Å; L115-F120 HydrophobicContact CB-CZ 4.38Å; L115-F120 HydrophobicContact CD1-CE2 4.17Å; L115-F120 HydrophobicContact CD1-CZ 3.93Å; E117-F120 PolarHBondContact O-N 3.18Å; F120-M122 PolarHBondContact O-N 3.32Å; F120-L497 HydrophobicContact CE1-CD1 3.85Å; F120-L497 HydrophobicContact CE1-CG 4.32Å; F120-L497 HydrophobicContact CZ-CD1 4.2Å; F120-A500 WeakPolarHBondContact CE2-O 3.38Å; F120-A500 HydrophobicContact CZ-CB 4.18Å; F120-A500 WeakPolarHBondContact CZ-O 3.22Å; F120-M501 HydrophobicContact CD1-CB 4.12Å; F120-M501 HydrophobicContact CD1-CE 4.12Å; F120-M501 HydrophobicContact CD1-CG 3.84Å; F120-M501 HydrophobicContact CE1-CB 3.88Å; F120-M501 HydrophobicContact CE1-CE 4.45Å; F120-M501 HydrophobicContact CE1-CG 4.14Å; F120-M501 HydrophobicContact CG-CG 4.28Å; F120-M501 HydrophobicContact CZ-CB 4.31Å; F120-P502 HydrophobicContact CD2-CG 3.95Å; F120-P502 HydrophobicContact CE2-CG 4.46Å; F120-Y505 HydrophobicContact CB-CD2 3.61Å; F120-Y505 HydrophobicContact CB-CE2 3.76Å; F120-Y505 HydrophobicContact CB-CG 4.35Å
121	D	58.3	Low	60.9	Low	30 Å²	30	68.9 Å²	68.9	16%	0.16	37%	0.365	C	S	.	.	S	Bend	trans	-65.5	123.6	176.1	-168.1	18.5	0	0	0	110.8	T123 K302	D121-T123 HydrophobicContact CB-CG2 4.28Å; D121-T123 PolarHBondContact O-N 2.93Å; D121-K302 VanDerWaalsContact OD1-CD 3.23Å; D121-K302 WeakPolarHBondContact OD1-CD 3.47Å; D121-K302 VanDerWaalsContact OD1-CE 3.22Å; D121-K302 WeakPolarHBondContact OD1-CE 3.23Å; D121-K302 IonicContact OD1-NZ 3.31Å; D121-K302 PolarHBondContact OD1-NZ 3.41Å; D121-K302 IonicContact OD2-NZ 3.54Å
122	M	58.5	Low	63.7	Low	6 Å²	6	64 Å²	64	3%	0.03	33%	0.331	C	S	.	.			trans	-71.5	76.1	176.4	-66.6	170.3	-81.8	0	0	109.7	V59 L62 F120 I296 T297 K302	V59-M122 HydrophobicContact CG1-CE 4.16Å; L62-M122 HydrophobicContact CB-CG 4.29Å; L62-M122 HydrophobicContact CB-SD 3.44Å; L62-M122 WeakPolarHBondContact CB-SD 3.23Å; L62-M122 HydrophobicContact CD1-SD 4.32Å; F120-M122 PolarHBondContact O-N 3.32Å; M122-I296 HydrophobicContact CE-CG2 3.46Å; M122-I296 VanDerWaalsContact CE-CG2 3.46Å; M122-I296 HydrophobicContact SD-CG2 4.07Å; M122-T297 WeakPolarHBondContact O-CG2 3.37Å; M122-K302 HydrophobicContact CE-CD 3.91Å
123	T	55	Low	66.4	Low	80 Å²	80	60.9 Å²	60.9	49%	0.491	31%	0.306	S	S	.	.			trans	-82.8	-32.9	177.9	49.9	0	0	0	0	111.8	D121	D121-T123 HydrophobicContact CB-CG2 4.28Å; D121-T123 PolarHBondContact O-N 2.93Å
124	E	57.9	Low	68.7	Low	66 Å²	66	55.3 Å²	55.3	31%	0.308	28%	0.281	S	S	.	.	S	Bend	trans	-93.4	139.4	177.2	-59.2	-160.4	155.7	0	0	111.9	R73 I126 T297	R73-E124 IonicContact CZ-OE1 2.78Å; R73-E124 IonicContact CZ-OE2 2.86Å; R73-E124 IonicContact NH1-OE1 3.02Å; R73-E124 PolarHBondContact NH1-OE1 2.91Å; R73-E124 IonicContact NH2-OE1 3.12Å; R73-E124 PolarHBondContact NH2-OE1 3.18Å; R73-E124 IonicContact NH2-OE2 2.74Å; R73-E124 PolarHBondContact NH2-OE2 3.29Å; E124-I126 VanDerWaalsContact C-N 3.26Å; E124-I126 HydrophobicContact CB-CG1 4.36Å; E124-I126 PolarHBondContact O-N 3.27Å; E124-T297 VanDerWaalsContact C-CG2 3.47Å; E124-T297 WeakPolarHBondContact O-CG2 3.44Å
125	R	58.7	Low	70.6	Confident	156 Å²	156	52.2 Å²	52.2	59%	0.589	25%	0.254	S	S	*	.			trans	-73.6	86.3	172.5	-70.7	-176	-176.5	-171.1	1.5	108.5	E127 T297	R125-E127 PolarHBondContact O-N 3.12Å; R125-T297 HydrophobicContact CB-CG2 4.34Å; R125-T297 HydrophobicContact CG-CG2 3.61Å
126	I	67.9	Low	72.2	Confident	8 Å²	8	51 Å²	51	4%	0.041	25%	0.248	C	C	.	.			trans	-82.8	106.4	169.7	-56.8	-177	0	0	0	106.9	V65 V69 E124 R130 A131 P293	V65-I126 HydrophobicContact CG1-CD1 4.03Å; V65-I126 HydrophobicContact CG1-CG2 4.08Å; V69-I126 HydrophobicContact CB-CD1 4.43Å; V69-I126 HydrophobicContact CG2-CD1 4.19Å; E124-I126 VanDerWaalsContact C-N 3.26Å; E124-I126 HydrophobicContact CB-CG1 4.36Å; E124-I126 PolarHBondContact O-N 3.27Å; I126-R130 HydrophobicContact CG2-CB 4.31Å; I126-R130 HydrophobicContact CG2-CG 4.46Å; I126-A131 HydrophobicContact CG2-CB 4.19Å; I126-P293 WeakPolarHBondContact O-CB 3.31Å
127	E	77.3	Confident	73.6	Confident	135 Å²	135	48.3 Å²	48.3	63%	0.631	24%	0.236	S	C	*	.			trans	-59.5	141.4	172.3	-63.2	-174.8	164	0	0	109.8	R125 G129 R130 A131	R125-E127 PolarHBondContact O-N 3.12Å; E127-G129 PolarHBondContact O-N 2.99Å; E127-R130 WeakPolarHBondContact O-CA 3.22Å; E127-R130 WeakPolarHBondContact O-CB 3.47Å; E127-R130 PolarHBondContact O-N 3.24Å; E127-A131 PolarHBondContact O-N 3.05Å; E127-A131 VanDerWaalsContact O-N 3.14Å
128	L	85.1	Confident	75.1	Confident	5 Å²	5	47.3 Å²	47.3	3%	0.026	23%	0.228	C	C	.	.	H	α-helix	trans	-57.4	-36.8	-177.2	-174	60	0	0	0	111.7	V58 R130 A131 V132 F144 P293 L486	V58-L128 HydrophobicContact CG1-CD1 4.04Å; L128-R130 VanDerWaalsContact C-N 3.26Å; L128-R130 PolarHBondContact O-N 2.98Å; L128-A131 WeakPolarHBondContact O-CB 3.43Å; L128-A131 PolarHBondContact O-N 3.3Å; L128-A131 VanDerWaalsContact O-N 3.15Å; L128-V132 VanDerWaalsContact O-CG2 3.3Å; L128-V132 WeakPolarHBondContact O-CG2 3.38Å; L128-V132 PolarHBondContact O-N 3.3Å; L128-F144 HydrophobicContact CB-CZ 4.07Å; L128-F144 HydrophobicContact CD2-CE2 3.71Å; L128-F144 HydrophobicContact CD2-CZ 4.06Å; L128-F144 HydrophobicContact CG-CE2 4.01Å; L128-F144 HydrophobicContact CG-CZ 4.07Å; L128-P293 HydrophobicContact CB-CG 4.05Å; L128-L486 HydrophobicContact CD1-CD1 4Å
129	G	84.2	Confident	76.6	Confident	2 Å²	2	46.8 Å²	46.8	2%	0.021	23%	0.228	C	C	.	.	H	α-helix	trans	-61.3	-31.4	175	0	0	0	0	0	113.9	E127 N133	E127-G129 PolarHBondContact O-N 2.99Å; G129-N133 PolarHBondContact O-N 3.4Å; G129-N133 VanDerWaalsContact O-N 3.1Å
130	R	84.9	Confident	78.3	Confident	124 Å²	124	45.7 Å²	45.7	47%	0.468	22%	0.224	S	C	.	.	H	α-helix	trans	-73.1	-42.7	173.3	-176.1	177.5	178.1	-170.3	-1.5	111.2	I126 E127 L128 V132 N133 I134	I126-R130 HydrophobicContact CG2-CB 4.31Å; I126-R130 HydrophobicContact CG2-CG 4.46Å; E127-R130 WeakPolarHBondContact O-CA 3.22Å; E127-R130 WeakPolarHBondContact O-CB 3.47Å; E127-R130 PolarHBondContact O-N 3.24Å; L128-R130 VanDerWaalsContact C-N 3.26Å; L128-R130 PolarHBondContact O-N 2.98Å; R130-V132 VanDerWaalsContact C-N 3.28Å; R130-V132 PolarHBondContact O-N 3.29Å; R130-N133 PolarHBondContact O-N 3.21Å; R130-I134 HydrophobicContact CG-CD1 4.04Å; R130-I134 WeakPolarHBondContact O-CG1 3.33Å; R130-I134 PolarHBondContact O-N 3.46Å
131	A	86.8	Confident	79.8	Confident	0 Å²	0	46.2 Å²	46.2	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-59.8	-41	174.5	0	0	0	0	0	111.6	L62 V65 I126 E127 L128 I134 L135	L62-A131 HydrophobicContact CD2-CB 4.47Å; V65-A131 HydrophobicContact CB-CB 4.43Å; V65-A131 HydrophobicContact CG1-CB 4.21Å; V65-A131 HydrophobicContact CG2-CB 4.15Å; I126-A131 HydrophobicContact CG2-CB 4.19Å; E127-A131 PolarHBondContact O-N 3.05Å; E127-A131 VanDerWaalsContact O-N 3.14Å; L128-A131 WeakPolarHBondContact O-CB 3.43Å; L128-A131 PolarHBondContact O-N 3.3Å; L128-A131 VanDerWaalsContact O-N 3.15Å; A131-I134 PolarHBondContact O-N 3.07Å; A131-L135 WeakPolarHBondContact O-CB 3.37Å; A131-L135 WeakPolarHBondContact O-CG 3.49Å; A131-L135 PolarHBondContact O-N 3.38Å
132	V	90.7	Very high	81.4	Confident	0 Å²	0	48.1 Å²	48.1	0%	0	24%	0.236	C	C	.	.	H	α-helix	trans	-60.2	-45.7	173.6	171.9	0	0	0	0	111.7	L128 R130 I134 L135 L136 G140 W141 F144 V482 L486	L128-V132 VanDerWaalsContact O-CG2 3.3Å; L128-V132 WeakPolarHBondContact O-CG2 3.38Å; L128-V132 PolarHBondContact O-N 3.3Å; R130-V132 VanDerWaalsContact C-N 3.28Å; R130-V132 PolarHBondContact O-N 3.29Å; V132-I134 PolarHBondContact O-N 3.48Å; V132-L135 PolarHBondContact O-N 3.34Å; V132-L136 HydrophobicContact CG1-CB 4.43Å; V132-L136 HydrophobicContact CG1-CD1 4.28Å; V132-L136 WeakPolarHBondContact O-CA 3.46Å; V132-L136 WeakPolarHBondContact O-CB 3.43Å; V132-L136 PolarHBondContact O-N 2.77Å; V132-G140 VanDerWaalsContact CG1-O 3.26Å; V132-G140 WeakPolarHBondContact CG1-O 3.44Å; V132-W141 HydrophobicContact CG1-CB 4.39Å; V132-F144 HydrophobicContact CB-CB 4.45Å; V132-F144 HydrophobicContact CG1-CB 3.94Å; V132-F144 HydrophobicContact CG2-CB 4.15Å; V132-F144 HydrophobicContact CG2-CD1 4.46Å; V132-F144 HydrophobicContact CG2-CD2 4.27Å; V132-F144 HydrophobicContact CG2-CG 4.02Å; V132-V482 HydrophobicContact CG2-CG1 3.87Å; V132-L486 HydrophobicContact CB-CD2 4.38Å; V132-L486 HydrophobicContact CG2-CD1 3.85Å; V132-L486 HydrophobicContact CG2-CD2 3.94Å; V132-L486 HydrophobicContact CG2-CG 4.32Å
133	N	88.6	Confident	83.1	Confident	41 Å²	41	51.1 Å²	51.1	22%	0.219	25%	0.248	C	C	.	.	H	α-helix	trans	-62	-43.4	177.9	-173.6	62.1	0	0	0	112.5	G129 R130 L135 G137 W141 P395	G129-N133 PolarHBondContact O-N 3.4Å; G129-N133 VanDerWaalsContact O-N 3.1Å; R130-N133 PolarHBondContact O-N 3.21Å; N133-L135 PolarHBondContact O-N 2.88Å; N133-G137 VanDerWaalsContact O-CA 3.29Å; N133-G137 WeakPolarHBondContact O-CA 3.45Å; N133-G137 PolarHBondContact O-N 2.99Å; N133-G137 VanDerWaalsContact O-N 3.12Å; N133-W141 HydrophobicContact CB-CB 4.33Å; N133-W141 HydrophobicContact CB-CG 4.32Å; N133-P395 WeakPolarHBondContact OD1-CG 3.06Å
134	I	86.8	Confident	85	Confident	45 Å²	45	47.6 Å²	47.6	23%	0.231	23%	0.226	C	C	.	.	H	α-helix	trans	-63.8	-40.8	-179.7	-69	167.1	0	0	0	111.2	V65 V69 R130 A131 V132	V65-I134 HydrophobicContact CG1-CD1 3.75Å; V69-I134 HydrophobicContact CG2-CD1 3.98Å; R130-I134 HydrophobicContact CG-CD1 4.04Å; R130-I134 WeakPolarHBondContact O-CG1 3.33Å; R130-I134 PolarHBondContact O-N 3.46Å; A131-I134 PolarHBondContact O-N 3.07Å; V132-I134 PolarHBondContact O-N 3.48Å
135	L	90.1	Very high	86.6	Confident	7 Å²	7	45.2 Å²	45.2	4%	0.037	22%	0.215	C	C	.	.	H	α-helix	trans	-92	-40.9	-172.7	-66.6	173.4	0	0	0	113.5	V61 V65 A131 V132 N133 L486 K489 V490 Y494	V61-L135 HydrophobicContact CG1-CD1 3.56Å; V65-L135 HydrophobicContact CG2-CD1 3.48Å; V65-L135 VanDerWaalsContact CG2-CD1 3.48Å; V65-L135 HydrophobicContact CG2-CD2 4.13Å; V65-L135 HydrophobicContact CG2-CG 3.78Å; A131-L135 WeakPolarHBondContact O-CB 3.37Å; A131-L135 WeakPolarHBondContact O-CG 3.49Å; A131-L135 PolarHBondContact O-N 3.38Å; V132-L135 PolarHBondContact O-N 3.34Å; N133-L135 PolarHBondContact O-N 2.88Å; L135-L486 HydrophobicContact CB-CD2 3.97Å; L135-L486 HydrophobicContact CD1-CD2 3.79Å; L135-K489 HydrophobicContact CB-CG 4.33Å; L135-K489 WeakPolarHBondContact O-CE 3.3Å; L135-K489 VanDerWaalsContact O-CG 3.31Å; L135-K489 WeakPolarHBondContact O-CG 3.44Å; L135-V490 HydrophobicContact CD1-CG2 3.46Å; L135-V490 VanDerWaalsContact CD1-CG2 3.46Å; L135-V490 HydrophobicContact CD2-CG2 3.83Å; L135-V490 HydrophobicContact CG-CG2 4.29Å; L135-Y494 HydrophobicContact CD2-CD2 3.72Å; L135-Y494 HydrophobicContact CD2-CE2 3.37Å
136	L	91.7	Very high	88.3	Confident	20 Å²	20	40.6 Å²	40.6	11%	0.105	20%	0.204	C	C	.	.	H	α-helix	trans	-109.4	-1.6	-170.3	-54.4	-177.5	0	0	0	113.3	V132 W485 L486 K489	V132-L136 HydrophobicContact CG1-CB 4.43Å; V132-L136 HydrophobicContact CG1-CD1 4.28Å; V132-L136 WeakPolarHBondContact O-CA 3.46Å; V132-L136 WeakPolarHBondContact O-CB 3.43Å; V132-L136 PolarHBondContact O-N 2.77Å; L136-W485 HydrophobicContact CD1-CB 4.09Å; L136-W485 HydrophobicContact CD1-CD2 3.52Å; L136-W485 HydrophobicContact CD1-CE3 3.68Å; L136-W485 HydrophobicContact CD1-CG 3.71Å; L136-W485 HydrophobicContact CD1-CZ3 4.3Å; L136-W485 HydrophobicContact CD2-CD2 4Å; L136-W485 HydrophobicContact CD2-CG 3.84Å; L136-W485 HydrophobicContact CG-CD2 4.3Å; L136-W485 HydrophobicContact CG-CG 4.44Å; L136-L486 HydrophobicContact CD1-CD2 3.68Å; L136-L486 HydrophobicContact CD1-CG 4.03Å; L136-L486 HydrophobicContact CD2-CD2 4.48Å; L136-L486 HydrophobicContact CG-CD2 3.75Å; L136-K489 HydrophobicContact CD2-CB 3.79Å; L136-K489 HydrophobicContact CD2-CG 4.05Å
137	G	89.4	Confident	89.6	Confident	30 Å²	30	40.8 Å²	40.8	31%	0.309	21%	0.206	S	C	.	.	H	α-helix	trans	64	-161.5	-177.8	0	0	0	0	0	113.4	N133 V139 G140 W141	N133-G137 VanDerWaalsContact O-CA 3.29Å; N133-G137 WeakPolarHBondContact O-CA 3.45Å; N133-G137 PolarHBondContact O-N 2.99Å; N133-G137 VanDerWaalsContact O-N 3.12Å; G137-V139 VanDerWaalsContact C-N 3.35Å; G137-V139 PolarHBondContact O-N 3.43Å; G137-G140 PolarHBondContact O-N 3.14Å; G137-W141 WeakPolarHBondContact O-CB 3.5Å; G137-W141 PolarHBondContact O-N 3.17Å
138	Y	88.8	Confident	90.4	Very high	100 Å²	100	34.8 Å²	34.8	39%	0.392	18%	0.178	S	C	.	.	H	α-helix	trans	-62	-37.9	-174	-177	-105.4	0	0	0	113.6	W141 L142 N394 P395	Y138-W141 AromaticContact CD2-CE3 3.94Å; Y138-W141 HydrophobicContact CD2-CE3 3.94Å; Y138-W141 HydrophobicContact CD2-CZ3 4.27Å; Y138-W141 AromaticContact CE2-CE3 3.81Å; Y138-W141 HydrophobicContact CE2-CE3 3.81Å; Y138-W141 AromaticContact CE2-CZ3 3.69Å; Y138-W141 HydrophobicContact CE2-CZ3 3.69Å; Y138-W141 PolarHBondContact O-N 3.26Å; Y138-L142 WeakPolarHBondContact O-CB 3.36Å; Y138-L142 PolarHBondContact O-N 2.89Å; Y138-N394 WeakPolarHBondContact CD2-OD1 2.89Å; Y138-P395 HydrophobicContact CD2-CG 4.48Å
139	V	90.9	Very high	90.8	Very high	104 Å²	104	35.9 Å²	35.9	63%	0.63	18%	0.183	S	C	*	.	H	α-helix	trans	-66.8	-48	-177.7	179.7	0	0	0	0	110.9	G137 W141 L142 F143 W485	G137-V139 VanDerWaalsContact C-N 3.35Å; G137-V139 PolarHBondContact O-N 3.43Å; V139-W141 VanDerWaalsContact C-N 3.31Å; V139-W141 PolarHBondContact O-N 3.16Å; V139-L142 PolarHBondContact O-N 3.03Å; V139-F143 PolarHBondContact O-N 3.16Å; V139-W485 HydrophobicContact CG1-CH2 4.43Å
140	G	92.1	Very high	91.4	Very high	1 Å²	1	40.3 Å²	40.3	1%	0.01	21%	0.206	C	C	.	.	H	α-helix	trans	-64.9	-37.8	176.1	0	0	0	0	0	112.2	V132 G137 F143 F144	V132-G140 VanDerWaalsContact CG1-O 3.26Å; V132-G140 WeakPolarHBondContact CG1-O 3.44Å; G137-G140 PolarHBondContact O-N 3.14Å; G140-F143 PolarHBondContact O-N 2.88Å; G140-F144 WeakPolarHBondContact O-CB 3.49Å; G140-F144 PolarHBondContact O-N 2.9Å
141	W	91.5	Very high	91.9	Very high	11 Å²	11	35 Å²	35	4%	0.042	19%	0.186	C	C	.	.	H	α-helix	trans	-60.6	-48.7	175	176.6	89.6	0	0	0	111.8	V132 N133 G137 Y138 V139 F143 F144 Y145 T388 L389 P395	V132-W141 HydrophobicContact CG1-CB 4.39Å; N133-W141 HydrophobicContact CB-CB 4.33Å; N133-W141 HydrophobicContact CB-CG 4.32Å; G137-W141 WeakPolarHBondContact O-CB 3.5Å; G137-W141 PolarHBondContact O-N 3.17Å; Y138-W141 AromaticContact CD2-CE3 3.94Å; Y138-W141 HydrophobicContact CD2-CE3 3.94Å; Y138-W141 HydrophobicContact CD2-CZ3 4.27Å; Y138-W141 AromaticContact CE2-CE3 3.81Å; Y138-W141 HydrophobicContact CE2-CE3 3.81Å; Y138-W141 AromaticContact CE2-CZ3 3.69Å; Y138-W141 HydrophobicContact CE2-CZ3 3.69Å; Y138-W141 PolarHBondContact O-N 3.26Å; V139-W141 VanDerWaalsContact C-N 3.31Å; V139-W141 PolarHBondContact O-N 3.16Å; W141-F143 VanDerWaalsContact C-N 3.33Å; W141-F143 PolarHBondContact O-N 3.3Å; W141-F144 PolarHBondContact O-N 3.48Å; W141-Y145 AromaticContact CD1-CD2 3.67Å; W141-Y145 AromaticContact CD1-CE2 3.4Å; W141-Y145 VanDerWaalsContact CD1-CE2 3.4Å; W141-Y145 AromaticContact CD2-CD2 3.95Å; W141-Y145 HydrophobicContact CD2-CD2 3.95Å; W141-Y145 HydrophobicContact CD2-CE2 4.31Å; W141-Y145 AromaticContact CE2-CD2 3.59Å; W141-Y145 AromaticContact CE2-CE2 3.63Å; W141-Y145 HydrophobicContact CG-CD2 4.02Å; W141-Y145 HydrophobicContact CG-CE2 4.2Å; W141-Y145 HydrophobicContact CZ2-CD2 4.15Å; W141-Y145 HydrophobicContact CZ2-CE2 4.25Å; W141-Y145 AromaticContact NE1-CD2 3.45Å; W141-Y145 AromaticContact NE1-CE2 3.03Å; W141-Y145 AromaticContact NE1-CZ 3.98Å; W141-Y145 WeakPolarHBondContact O-CD2 3.4Å; W141-Y145 PolarHBondContact O-N 2.93Å; W141-T388 WeakPolarHBondContact CH2-O 3.19Å; W141-T388 HydrophobicContact CZ2-CG2 3.72Å; W141-L389 HydrophobicContact CH2-CD1 4.07Å; W141-L389 HydrophobicContact CZ3-CD1 3.83Å; W141-P395 HydrophobicContact CD2-CG 4.43Å
142	L	92.9	Very high	92.3	Very high	70 Å²	70	35.2 Å²	35.2	37%	0.366	19%	0.187	S	C	.	.	H	α-helix	trans	-59.3	-44.9	177.6	-174.2	77.3	0	0	0	111.3	Y138 V139 T146 L389	Y138-L142 WeakPolarHBondContact O-CB 3.36Å; Y138-L142 PolarHBondContact O-N 2.89Å; V139-L142 PolarHBondContact O-N 3.03Å; L142-T146 WeakPolarHBondContact O-CB 3.2Å; L142-T146 PolarHBondContact O-N 2.8Å; L142-T146 PolarHBondContact O-OG1 3.1Å; L142-L389 HydrophobicContact CD1-CD1 3.56Å
143	F	94.4	Very high	92.6	Very high	68 Å²	68	38 Å²	38	30%	0.298	20%	0.2	S	C	.	.	H	α-helix	trans	-60.4	-50.9	177.1	178.2	-103.8	0	0	0	111.9	V139 G140 W141 Y145 T146 C147 I481 V482	V139-F143 PolarHBondContact O-N 3.16Å; G140-F143 PolarHBondContact O-N 2.88Å; W141-F143 VanDerWaalsContact C-N 3.33Å; W141-F143 PolarHBondContact O-N 3.3Å; F143-Y145 PolarHBondContact O-N 3.39Å; F143-T146 PolarHBondContact O-N 2.95Å; F143-C147 PolarHBondContact O-N 3.1Å; F143-C147 PolarHBondContact O-SG 3.15Å; F143-I481 HydrophobicContact CE1-CB 4.1Å; F143-I481 HydrophobicContact CE1-CG2 3.62Å; F143-I481 HydrophobicContact CZ-CB 4.25Å; F143-I481 HydrophobicContact CZ-CD1 4.11Å; F143-I481 HydrophobicContact CZ-CG2 3.85Å; F143-V482 HydrophobicContact CD1-CG2 3.8Å; F143-V482 HydrophobicContact CE1-CG2 3.74Å
144	F	93.9	Very high	92.9	Very high	7 Å²	7	36.3 Å²	36.3	3%	0.031	19%	0.192	C	C	.	.	H	α-helix	trans	-57.9	-49.7	179.7	170.3	-102.8	0	0	0	112.3	L128 V132 G140 W141 T146 C147 M148 I478 V482	L128-F144 HydrophobicContact CB-CZ 4.07Å; L128-F144 HydrophobicContact CD2-CE2 3.71Å; L128-F144 HydrophobicContact CD2-CZ 4.06Å; L128-F144 HydrophobicContact CG-CE2 4.01Å; L128-F144 HydrophobicContact CG-CZ 4.07Å; V132-F144 HydrophobicContact CB-CB 4.45Å; V132-F144 HydrophobicContact CG1-CB 3.94Å; V132-F144 HydrophobicContact CG2-CB 4.15Å; V132-F144 HydrophobicContact CG2-CD1 4.46Å; V132-F144 HydrophobicContact CG2-CD2 4.27Å; V132-F144 HydrophobicContact CG2-CG 4.02Å; G140-F144 WeakPolarHBondContact O-CB 3.49Å; G140-F144 PolarHBondContact O-N 2.9Å; W141-F144 PolarHBondContact O-N 3.48Å; F144-T146 VanDerWaalsContact C-N 3.31Å; F144-T146 PolarHBondContact O-N 3.43Å; F144-C147 PolarHBondContact O-N 3.15Å; F144-M148 HydrophobicContact CD1-CG 4.27Å; F144-M148 HydrophobicContact CD2-CG 4.14Å; F144-M148 HydrophobicContact CE1-CG 3.8Å; F144-M148 HydrophobicContact CE2-CG 3.67Å; F144-M148 HydrophobicContact CE2-SD 4.04Å; F144-M148 HydrophobicContact CG-CG 4.44Å; F144-M148 HydrophobicContact CZ-CG 3.49Å; F144-M148 VanDerWaalsContact CZ-CG 3.49Å; F144-M148 HydrophobicContact CZ-SD 3.97Å; F144-M148 WeakPolarHBondContact O-CB 3.22Å; F144-M148 WeakPolarHBondContact O-CG 3.44Å; F144-M148 PolarHBondContact O-N 3.09Å; F144-I478 HydrophobicContact CE2-CG2 4.35Å; F144-V482 HydrophobicContact CB-CG2 4.25Å; F144-V482 HydrophobicContact CD2-CB 4.5Å; F144-V482 HydrophobicContact CD2-CG1 3.92Å; F144-V482 HydrophobicContact CD2-CG2 4.14Å
145	Y	92.6	Very high	93.3	Very high	15 Å²	15	34.6 Å²	34.6	6%	0.059	18%	0.183	C	C	.	.	H	α-helix	trans	-66.2	-33.8	-179.8	-85.6	-81.7	0	0	0	112.3	W141 F143 M148 I149 N385 T388	W141-Y145 AromaticContact CD1-CD2 3.67Å; W141-Y145 AromaticContact CD1-CE2 3.4Å; W141-Y145 VanDerWaalsContact CD1-CE2 3.4Å; W141-Y145 AromaticContact CD2-CD2 3.95Å; W141-Y145 HydrophobicContact CD2-CD2 3.95Å; W141-Y145 HydrophobicContact CD2-CE2 4.31Å; W141-Y145 AromaticContact CE2-CD2 3.59Å; W141-Y145 AromaticContact CE2-CE2 3.63Å; W141-Y145 HydrophobicContact CG-CD2 4.02Å; W141-Y145 HydrophobicContact CG-CE2 4.2Å; W141-Y145 HydrophobicContact CZ2-CD2 4.15Å; W141-Y145 HydrophobicContact CZ2-CE2 4.25Å; W141-Y145 AromaticContact NE1-CD2 3.45Å; W141-Y145 AromaticContact NE1-CE2 3.03Å; W141-Y145 AromaticContact NE1-CZ 3.98Å; W141-Y145 WeakPolarHBondContact O-CD2 3.4Å; W141-Y145 PolarHBondContact O-N 2.93Å; F143-Y145 PolarHBondContact O-N 3.39Å; Y145-M148 PolarHBondContact O-N 3.41Å; Y145-I149 WeakPolarHBondContact O-CB 3.27Å; Y145-I149 WeakPolarHBondContact O-CD1 3.48Å; Y145-I149 WeakPolarHBondContact O-CG1 3.46Å; Y145-I149 PolarHBondContact O-N 2.79Å; Y145-N385 HydrophobicContact CD1-CB 4.19Å; Y145-N385 WeakPolarHBondContact CD1-OD1 3.32Å; Y145-N385 HydrophobicContact CE1-CB 4.47Å; Y145-N385 WeakPolarHBondContact CE1-OD1 3.41Å; Y145-T388 HydrophobicContact CD1-CG2 4.3Å; Y145-T388 HydrophobicContact CE1-CG2 3.64Å; Y145-T388 HydrophobicContact CE2-CG2 4.19Å
146	T	94.5	Very high	93.6	Very high	59 Å²	59	34.3 Å²	34.3	36%	0.362	18%	0.181	S	C	.	.	H	α-helix	trans	-62.8	-49.6	173.5	-57.9	0	0	0	0	111.1	L142 F143 F144 M148 I149 L150	L142-T146 WeakPolarHBondContact O-CB 3.2Å; L142-T146 PolarHBondContact O-N 2.8Å; L142-T146 PolarHBondContact O-OG1 3.1Å; F143-T146 PolarHBondContact O-N 2.95Å; F144-T146 VanDerWaalsContact C-N 3.31Å; F144-T146 PolarHBondContact O-N 3.43Å; T146-M148 VanDerWaalsContact C-N 3.34Å; T146-M148 PolarHBondContact O-N 2.83Å; T146-I149 PolarHBondContact O-N 3.34Å; T146-L150 HydrophobicContact CG2-CD1 4.23Å; T146-L150 WeakPolarHBondContact O-CG 3.48Å; T146-L150 PolarHBondContact O-N 3.31Å
147	C	95.3	Very high	93.9	Very high	12 Å²	12	33.4 Å²	33.4	8%	0.081	18%	0.177	C	C	.	.	H	α-helix	trans	-61.6	-41.8	176.4	-63.7	0	0	0	0	111.9	F143 F144 I149 L150 Y151 I478	F143-C147 PolarHBondContact O-N 3.1Å; F143-C147 PolarHBondContact O-SG 3.15Å; F144-C147 PolarHBondContact O-N 3.15Å; C147-I149 PolarHBondContact O-N 3.1Å; C147-L150 PolarHBondContact O-N 3.14Å; C147-Y151 WeakPolarHBondContact O-CB 3.4Å; C147-Y151 PolarHBondContact O-N 2.87Å; C147-I478 HydrophobicContact CB-CD1 4.29Å; C147-I478 HydrophobicContact CB-CG1 3.7Å
148	M	92.7	Very high	94.2	Very high	9 Å²	9	32 Å²	32	4%	0.044	16%	0.162	C	C	.	.	H	α-helix	trans	-59.9	-44.8	175.9	-78.2	-62.6	-58.7	0	0	112.6	F144 Y145 T146 Y151 L152 H290 I478	F144-M148 HydrophobicContact CD1-CG 4.27Å; F144-M148 HydrophobicContact CD2-CG 4.14Å; F144-M148 HydrophobicContact CE1-CG 3.8Å; F144-M148 HydrophobicContact CE2-CG 3.67Å; F144-M148 HydrophobicContact CE2-SD 4.04Å; F144-M148 HydrophobicContact CG-CG 4.44Å; F144-M148 HydrophobicContact CZ-CG 3.49Å; F144-M148 VanDerWaalsContact CZ-CG 3.49Å; F144-M148 HydrophobicContact CZ-SD 3.97Å; F144-M148 WeakPolarHBondContact O-CB 3.22Å; F144-M148 WeakPolarHBondContact O-CG 3.44Å; F144-M148 PolarHBondContact O-N 3.09Å; Y145-M148 PolarHBondContact O-N 3.41Å; T146-M148 VanDerWaalsContact C-N 3.34Å; T146-M148 PolarHBondContact O-N 2.83Å; M148-Y151 PolarHBondContact O-N 3.41Å; M148-L152 HydrophobicContact CE-CD1 4.09Å; M148-L152 HydrophobicContact CE-CG 4.38Å; M148-L152 WeakPolarHBondContact O-CB 3.32Å; M148-L152 VanDerWaalsContact O-CG 3.23Å; M148-L152 WeakPolarHBondContact O-CG 3.46Å; M148-L152 PolarHBondContact O-N 2.95Å; M148-H290 HydrophobicContact CE-CB 3.73Å; M148-H290 HydrophobicContact SD-CB 3.35Å; M148-H290 WeakPolarHBondContact SD-CB 3.28Å; M148-I478 HydrophobicContact CG-CD1 4.27Å; M148-I478 HydrophobicContact CG-CG1 4.44Å; M148-I478 HydrophobicContact SD-CD1 3.6Å; M148-I478 HydrophobicContact SD-CG1 4.08Å; M148-I478 HydrophobicContact SD-CG2 4.17Å
149	I	94.7	Very high	94.5	Very high	28 Å²	28	28 Å²	28	14%	0.144	15%	0.147	C	C	.	.	H	α-helix	trans	-62.8	-47	177.8	-74.1	165.5	0	0	0	110.4	Y145 T146 C147 Y151 F153 L382 N385 I386 L389	Y145-I149 WeakPolarHBondContact O-CB 3.27Å; Y145-I149 WeakPolarHBondContact O-CD1 3.48Å; Y145-I149 WeakPolarHBondContact O-CG1 3.46Å; Y145-I149 PolarHBondContact O-N 2.79Å; T146-I149 PolarHBondContact O-N 3.34Å; C147-I149 PolarHBondContact O-N 3.1Å; I149-Y151 VanDerWaalsContact C-N 3.34Å; I149-Y151 PolarHBondContact O-N 3.37Å; I149-F153 WeakPolarHBondContact O-CB 3.39Å; I149-F153 PolarHBondContact O-N 3.4Å; I149-L382 HydrophobicContact CB-CD1 4.11Å; I149-L382 HydrophobicContact CG1-CD1 4.15Å; I149-L382 HydrophobicContact CG2-CD1 3.89Å; I149-L382 WeakPolarHBondContact O-CD1 3.46Å; I149-N385 HydrophobicContact CG1-CB 3.97Å; I149-I386 HydrophobicContact CD1-CB 4.44Å; I149-I386 HydrophobicContact CD1-CG1 3.87Å; I149-I386 HydrophobicContact CG1-CG1 3.9Å; I149-I386 HydrophobicContact CG2-CG1 4.09Å; I149-L389 HydrophobicContact CD1-CB 3.99Å; I149-L389 HydrophobicContact CD1-CD2 3.42Å; I149-L389 VanDerWaalsContact CD1-CD2 3.42Å; I149-L389 HydrophobicContact CD1-CG 4.33Å
150	L	95.9	Very high	94.8	Very high	95 Å²	95	23.1 Å²	23.1	50%	0.497	12%	0.117	S	C	.	.	H	α-helix	trans	-63.1	-39.8	178.1	-68.6	174.5	0	0	0	112.2	T146 C147 G154 A474	T146-L150 HydrophobicContact CG2-CD1 4.23Å; T146-L150 WeakPolarHBondContact O-CG 3.48Å; T146-L150 PolarHBondContact O-N 3.31Å; C147-L150 PolarHBondContact O-N 3.14Å; L150-G154 PolarHBondContact O-N 2.9Å; L150-A474 HydrophobicContact CB-CB 3.83Å
151	Y	95.6	Very high	95	Very high	12 Å²	12	23 Å²	23	5%	0.047	12%	0.116	C	C	.	.	H	α-helix	trans	-65.9	-51.4	178.2	-179.3	-97.5	0	0	0	111.7	C147 M148 I149 F153 G154 D155 Y284 M287 H290 T470 A474 I478	C147-Y151 WeakPolarHBondContact O-CB 3.4Å; C147-Y151 PolarHBondContact O-N 2.87Å; M148-Y151 PolarHBondContact O-N 3.41Å; I149-Y151 VanDerWaalsContact C-N 3.34Å; I149-Y151 PolarHBondContact O-N 3.37Å; Y151-F153 VanDerWaalsContact C-N 3.28Å; Y151-F153 PolarHBondContact O-N 3.3Å; Y151-G154 WeakPolarHBondContact O-CA 3.34Å; Y151-G154 PolarHBondContact O-N 3.42Å; Y151-G154 VanDerWaalsContact O-N 3.07Å; Y151-D155 VanDerWaalsContact CE1-OD2 3.25Å; Y151-D155 WeakPolarHBondContact CE1-OD2 3.45Å; Y151-D155 PolarHBondContact O-N 3.45Å; Y151-Y284 AromaticContact CE2-CD2 3.78Å; Y151-Y284 HydrophobicContact CE2-CD2 3.78Å; Y151-Y284 AromaticContact CE2-CE2 3.88Å; Y151-Y284 HydrophobicContact CE2-CE2 3.88Å; Y151-Y284 AromaticContact CZ-CE2 4Å; Y151-M287 HydrophobicContact CD1-CE 4.3Å; Y151-M287 HydrophobicContact CD2-CE 4.12Å; Y151-M287 HydrophobicContact CE1-CE 4.26Å; Y151-M287 HydrophobicContact CE1-CG 4.22Å; Y151-M287 HydrophobicContact CE2-CB 4.4Å; Y151-M287 HydrophobicContact CE2-CE 4.09Å; Y151-M287 HydrophobicContact CE2-CG 3.69Å; Y151-M287 HydrophobicContact CG-CE 4.23Å; Y151-M287 VanDerWaalsContact CZ-CG 3.49Å; Y151-M287 VanDerWaalsContact OH-CG 3.3Å; Y151-M287 WeakPolarHBondContact OH-CG 3.47Å; Y151-H290 AromaticContact CE1-CE1 3.82Å; Y151-T470 HydrophobicContact CD2-CG2 3.84Å; Y151-T470 HydrophobicContact CE2-CG2 4.2Å; Y151-A474 HydrophobicContact CD2-CB 4.48Å; Y151-I478 HydrophobicContact CD1-CD1 4.44Å; Y151-I478 HydrophobicContact CG-CD1 3.94Å
152	L	95	Very high	95.2	Very high	6 Å²	6	22.7 Å²	22.7	3%	0.031	12%	0.115	C	C	.	.	H	α-helix	trans	-66.5	-31.7	179.5	-66.1	170.7	0	0	0	112	M148 L156 I378 T381 L382	M148-L152 HydrophobicContact CE-CD1 4.09Å; M148-L152 HydrophobicContact CE-CG 4.38Å; M148-L152 WeakPolarHBondContact O-CB 3.32Å; M148-L152 VanDerWaalsContact O-CG 3.23Å; M148-L152 WeakPolarHBondContact O-CG 3.46Å; M148-L152 PolarHBondContact O-N 2.95Å; L152-L156 WeakPolarHBondContact O-CG 3.2Å; L152-L156 PolarHBondContact O-N 2.93Å; L152-L156 VanDerWaalsContact O-N 3.16Å; L152-I378 HydrophobicContact CB-CG2 4.32Å; L152-I378 HydrophobicContact CD2-CG2 3.96Å; L152-T381 HydrophobicContact CD1-CG2 3.84Å; L152-T381 HydrophobicContact CD2-CG2 4.47Å; L152-L382 HydrophobicContact CB-CB 4.04Å; L152-L382 HydrophobicContact CB-CD1 4.02Å; L152-L382 HydrophobicContact CB-CG 4.45Å; L152-L382 HydrophobicContact CD1-CB 4.38Å
153	F	96.3	Very high	95.3	Very high	59 Å²	59	19.5 Å²	19.5	26%	0.259	10%	0.099	S	C	.	.	H	α-helix	trans	-61	-48.1	169.1	170.4	-93.2	0	0	0	111.1	I149 Y151 D155 L156 A157 L382 V452 P453 V456	I149-F153 WeakPolarHBondContact O-CB 3.39Å; I149-F153 PolarHBondContact O-N 3.4Å; Y151-F153 VanDerWaalsContact C-N 3.28Å; Y151-F153 PolarHBondContact O-N 3.3Å; F153-D155 PolarHBondContact O-N 3.03Å; F153-L156 PolarHBondContact O-N 3.4Å; F153-A157 PolarHBondContact O-N 3.49Å; F153-L382 HydrophobicContact CB-CD2 4.25Å; F153-V452 HydrophobicContact CD2-CG1 4.48Å; F153-V452 HydrophobicContact CE2-CB 3.86Å; F153-V452 HydrophobicContact CE2-CG1 3.42Å; F153-V452 VanDerWaalsContact CE2-CG1 3.42Å; F153-V452 HydrophobicContact CZ-CG1 3.87Å; F153-P453 HydrophobicContact CD2-CB 4.36Å; F153-P453 HydrophobicContact CD2-CG 3.63Å; F153-P453 HydrophobicContact CE2-CB 4.1Å; F153-P453 HydrophobicContact CE2-CG 3.64Å; F153-V456 HydrophobicContact CE1-CG2 4.34Å; F153-V456 HydrophobicContact CZ-CG2 3.81Å
154	G	96.2	Very high	95.3	Very high	5 Å²	5	16.3 Å²	16.3	5%	0.052	9%	0.085	C	C	.	.	H	α-helix	trans	-57.9	-46.1	175.4	0	0	0	0	0	112.4	L150 Y151 L156 A157 I158 T470	L150-G154 PolarHBondContact O-N 2.9Å; Y151-G154 WeakPolarHBondContact O-CA 3.34Å; Y151-G154 PolarHBondContact O-N 3.42Å; Y151-G154 VanDerWaalsContact O-N 3.07Å; G154-L156 VanDerWaalsContact C-N 3.33Å; G154-L156 PolarHBondContact O-N 2.81Å; G154-A157 PolarHBondContact O-N 2.92Å; G154-A157 VanDerWaalsContact O-N 3.11Å; G154-I158 WeakPolarHBondContact O-CD1 3.35Å; G154-I158 WeakPolarHBondContact O-CG1 3.26Å; G154-I158 PolarHBondContact O-N 2.89Å; G154-T470 WeakPolarHBondContact CA-OG1 3.12Å
155	D	95.6	Very high	95.3	Very high	9 Å²	9	16.8 Å²	16.8	5%	0.048	9%	0.087	C	C	.	.	H	α-helix	trans	-53.4	-48.1	174.1	-79.6	-20.1	0	0	0	112.1	Y151 F153 A157 I158 Y159 Y284 I378	Y151-D155 VanDerWaalsContact CE1-OD2 3.25Å; Y151-D155 WeakPolarHBondContact CE1-OD2 3.45Å; Y151-D155 PolarHBondContact O-N 3.45Å; F153-D155 PolarHBondContact O-N 3.03Å; D155-A157 VanDerWaalsContact C-N 3.34Å; D155-A157 PolarHBondContact O-N 3.32Å; D155-I158 PolarHBondContact O-N 3.42Å; D155-Y159 WeakPolarHBondContact O-CB 3.3Å; D155-Y159 WeakPolarHBondContact O-CD1 3.14Å; D155-Y159 PolarHBondContact O-N 3.48Å; D155-Y284 WeakPolarHBondContact OD1-CE2 3.39Å; D155-Y284 PolarHBondContact OD1-OH 3.39Å; D155-I378 HydrophobicContact CB-CD1 4.01Å; D155-I378 HydrophobicContact CB-CG2 3.97Å
156	L	96.1	Very high	95.4	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-65.6	-36.9	178.8	-66.9	173.9	0	0	0	112.3	L152 F153 G154 Y159 G160 Y375 I378 L382 V449 P453	L152-L156 WeakPolarHBondContact O-CG 3.2Å; L152-L156 PolarHBondContact O-N 2.93Å; L152-L156 VanDerWaalsContact O-N 3.16Å; F153-L156 PolarHBondContact O-N 3.4Å; G154-L156 VanDerWaalsContact C-N 3.33Å; G154-L156 PolarHBondContact O-N 2.81Å; L156-Y159 PolarHBondContact O-N 3.12Å; L156-G160 PolarHBondContact O-N 3.24Å; L156-Y375 HydrophobicContact CB-CE2 3.97Å; L156-Y375 HydrophobicContact CD2-CD1 4.45Å; L156-Y375 HydrophobicContact CD2-CD2 3.55Å; L156-Y375 HydrophobicContact CD2-CE1 4.41Å; L156-Y375 HydrophobicContact CD2-CE2 3.52Å; L156-Y375 HydrophobicContact CD2-CG 4.05Å; L156-Y375 WeakPolarHBondContact CD2-O 3.28Å; L156-Y375 HydrophobicContact CG-CE2 4.33Å; L156-Y375 WeakPolarHBondContact O-CE2 3.48Å; L156-I378 HydrophobicContact CD1-CG2 4.5Å; L156-I378 HydrophobicContact CD2-CB 3.9Å; L156-I378 HydrophobicContact CD2-CG2 3.76Å; L156-I378 HydrophobicContact CG-CB 4.49Å; L156-I378 HydrophobicContact CG-CG2 3.8Å; L156-L382 HydrophobicContact CD1-CB 4.4Å; L156-L382 HydrophobicContact CD1-CD2 3.61Å; L156-V449 HydrophobicContact CD1-CG1 4.1Å; L156-P453 HydrophobicContact CB-CB 3.6Å; L156-P453 HydrophobicContact CB-CG 3.73Å; L156-P453 HydrophobicContact CD1-CG 4.1Å
157	A	97.1	Very high	95.4	Very high	1 Å²	1	15.6 Å²	15.6	1%	0.008	8%	0.079	C	C	.	.	H	α-helix	trans	-66.7	-45.8	176.9	0	0	0	0	0	110.9	F153 G154 D155 Y159 G160 A161 P453 V456	F153-A157 PolarHBondContact O-N 3.49Å; G154-A157 PolarHBondContact O-N 2.92Å; G154-A157 VanDerWaalsContact O-N 3.11Å; D155-A157 VanDerWaalsContact C-N 3.34Å; D155-A157 PolarHBondContact O-N 3.32Å; A157-Y159 VanDerWaalsContact C-N 3.31Å; A157-Y159 PolarHBondContact O-N 2.72Å; A157-G160 CarbonylContact O-C 3.52Å; A157-G160 PolarHBondContact O-N 3.06Å; A157-A161 PolarHBondContact O-N 3.47Å; A157-P453 HydrophobicContact CB-CB 4.17Å; A157-V456 HydrophobicContact CB-CB 4.26Å; A157-V456 HydrophobicContact CB-CG1 4.22Å
158	I	96.1	Very high	95.3	Very high	0 Å²	0	15.1 Å²	15.1	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-57.7	-46	174.7	-65.7	157	0	0	0	110	G154 D155 G160 A161 V162 Y284 V463 L466 I467 T470	G154-I158 WeakPolarHBondContact O-CD1 3.35Å; G154-I158 WeakPolarHBondContact O-CG1 3.26Å; G154-I158 PolarHBondContact O-N 2.89Å; D155-I158 PolarHBondContact O-N 3.42Å; I158-G160 VanDerWaalsContact C-N 3.33Å; I158-G160 PolarHBondContact O-N 3.4Å; I158-A161 PolarHBondContact O-N 2.82Å; I158-A161 VanDerWaalsContact O-N 3.1Å; I158-V162 HydrophobicContact CG2-CG2 3.95Å; I158-V162 WeakPolarHBondContact O-CB 3.49Å; I158-V162 VanDerWaalsContact O-CG2 3.27Å; I158-V162 WeakPolarHBondContact O-CG2 3.32Å; I158-V162 PolarHBondContact O-N 3.17Å; I158-Y284 HydrophobicContact CD1-CE2 3.8Å; I158-V463 HydrophobicContact CG2-CG1 4.37Å; I158-L466 HydrophobicContact CG1-CB 3.78Å; I158-I467 HydrophobicContact CD1-CB 4.38Å; I158-I467 HydrophobicContact CD1-CG1 3.65Å; I158-I467 HydrophobicContact CG1-CG1 3.85Å; I158-I467 HydrophobicContact CG2-CD1 4.13Å; I158-I467 HydrophobicContact CG2-CG1 3.84Å; I158-T470 HydrophobicContact CD1-CG2 4.45Å
159	Y	95.5	Very high	95.1	Very high	18 Å²	18	15.3 Å²	15.3	7%	0.071	8%	0.077	C	C	.	.	H	α-helix	trans	-67.7	-38.7	-178.1	-73.6	18.4	0	0	0	111.3	T23 D155 L156 A157 A161 V163 I371 N374 Y375 I378	T23-Y159 HydrophobicContact CG2-CD1 4.06Å; T23-Y159 HydrophobicContact CG2-CE1 3.47Å; T23-Y159 VanDerWaalsContact CG2-CE1 3.47Å; D155-Y159 WeakPolarHBondContact O-CB 3.3Å; D155-Y159 WeakPolarHBondContact O-CD1 3.14Å; D155-Y159 PolarHBondContact O-N 3.48Å; L156-Y159 PolarHBondContact O-N 3.12Å; A157-Y159 VanDerWaalsContact C-N 3.31Å; A157-Y159 PolarHBondContact O-N 2.72Å; Y159-A161 PolarHBondContact O-N 3Å; Y159-V163 PolarHBondContact O-N 3.34Å; Y159-I371 VanDerWaalsContact CB-CG2 3.44Å; Y159-I371 HydrophobicContact CD1-CG2 3.55Å; Y159-I371 HydrophobicContact CD2-CG2 3.28Å; Y159-I371 HydrophobicContact CE1-CG2 4.1Å; Y159-I371 HydrophobicContact CE2-CG2 3.81Å; Y159-I371 HydrophobicContact CG-CG2 3.12Å; Y159-N374 HydrophobicContact CE2-CB 3.73Å; Y159-Y375 HydrophobicContact CD2-CD2 4.24Å; Y159-Y375 HydrophobicContact CG-CD2 4.47Å; Y159-I378 HydrophobicContact CD2-CD1 4.16Å; Y159-I378 HydrophobicContact CE2-CD1 3.35Å; Y159-I378 HydrophobicContact CE2-CG1 4.5Å
160	G	96.2	Very high	94.9	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-65.1	-19	172.4	0	0	0	0	0	114.1	L156 A157 I158 P164 A457	L156-G160 PolarHBondContact O-N 3.24Å; A157-G160 CarbonylContact O-C 3.52Å; A157-G160 PolarHBondContact O-N 3.06Å; I158-G160 VanDerWaalsContact C-N 3.33Å; I158-G160 PolarHBondContact O-N 3.4Å; G160-P164 WeakPolarHBondContact O-CD 3.36Å; G160-P164 WeakPolarHBondContact O-CG 3.36Å; G160-A457 VanDerWaalsContact C-CB 3.45Å; G160-A457 WeakPolarHBondContact O-CB 3.43Å
161	A	96.1	Very high	94.6	Very high	0 Å²	0	13.3 Å²	13.3	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-96.2	-48.2	174.8	0	0	0	0	0	112.5	A157 I158 Y159 V163 P164 K165 Y210 A457 V463 L466	A157-A161 PolarHBondContact O-N 3.47Å; I158-A161 PolarHBondContact O-N 2.82Å; I158-A161 VanDerWaalsContact O-N 3.1Å; Y159-A161 PolarHBondContact O-N 3Å; A161-V163 PolarHBondContact O-N 3.12Å; A161-P164 WeakPolarHBondContact O-CD 3.42Å; A161-K165 WeakPolarHBondContact O-CB 3.47Å; A161-K165 PolarHBondContact O-N 3.04Å; A161-Y210 WeakPolarHBondContact CA-OH 3.49Å; A161-A457 HydrophobicContact CB-CB 4.27Å; A161-V463 HydrophobicContact CB-CG2 4.13Å; A161-L466 HydrophobicContact CB-CD1 3.78Å
162	V	95.7	Very high	94.3	Very high	3 Å²	3	13.1 Å²	13.1	2%	0.018	7%	0.068	C	C	.	.	H	α-helix	trans	-61.2	-44.4	-176.2	174.7	0	0	0	0	112	I158 S166 V337 P367 I371 V463	I158-V162 HydrophobicContact CG2-CG2 3.95Å; I158-V162 WeakPolarHBondContact O-CB 3.49Å; I158-V162 VanDerWaalsContact O-CG2 3.27Å; I158-V162 WeakPolarHBondContact O-CG2 3.32Å; I158-V162 PolarHBondContact O-N 3.17Å; V162-S166 VanDerWaalsContact O-CB 3.32Å; V162-S166 WeakPolarHBondContact O-CB 3.26Å; V162-S166 PolarHBondContact O-N 2.87Å; V162-S166 PolarHBondContact O-OG 2.9Å; V162-V337 HydrophobicContact CG1-CG1 4.18Å; V162-V337 HydrophobicContact CG1-CG2 4.34Å; V162-V337 HydrophobicContact CG2-CG2 4.2Å; V162-P367 HydrophobicContact CG1-CB 3.83Å; V162-I371 HydrophobicContact CB-CD1 4Å; V162-I371 HydrophobicContact CG1-CD1 3.44Å; V162-I371 VanDerWaalsContact CG1-CD1 3.44Å; V162-V463 HydrophobicContact CG2-CB 4.22Å; V162-V463 HydrophobicContact CG2-CG1 3.45Å; V162-V463 VanDerWaalsContact CG2-CG1 3.45Å; V162-V463 HydrophobicContact CG2-CG2 3.65Å
163	V	95.3	Very high	93.7	Very high	4 Å²	4	17.6 Å²	17.6	2%	0.024	10%	0.096	C	C	.	.	H	α-helix	trans	-67.1	-51.6	-177	171.4	0	0	0	0	110.9	Y159 A161 K165 S166 L167 F217 V368 I371	Y159-V163 PolarHBondContact O-N 3.34Å; A161-V163 PolarHBondContact O-N 3.12Å; V163-K165 PolarHBondContact O-N 3.15Å; V163-S166 PolarHBondContact O-N 3.11Å; V163-L167 PolarHBondContact O-N 3.05Å; V163-F217 HydrophobicContact CB-CD2 4.02Å; V163-F217 HydrophobicContact CB-CE2 3.74Å; V163-F217 HydrophobicContact CG1-CD2 3.59Å; V163-F217 HydrophobicContact CG1-CE2 3.68Å; V163-F217 HydrophobicContact CG2-CE2 3.95Å; V163-V368 HydrophobicContact CG1-CB 4.38Å; V163-V368 HydrophobicContact CG1-CG1 4.15Å; V163-V368 HydrophobicContact CG1-CG2 4.25Å; V163-I371 HydrophobicContact CG2-CB 3.78Å; V163-I371 HydrophobicContact CG2-CG2 3.83Å
164	P	95.7	Very high	93	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-62.5	-38	175.3	-29.5	41.9	0	0	0	114.2	G160 A161 S166 L167 M168 Y210 I213 V214 F217	G160-P164 WeakPolarHBondContact O-CD 3.36Å; G160-P164 WeakPolarHBondContact O-CG 3.36Å; A161-P164 WeakPolarHBondContact O-CD 3.42Å; P164-S166 PolarHBondContact O-N 2.95Å; P164-L167 PolarHBondContact O-N 2.98Å; P164-M168 VanDerWaalsContact O-CB 3.24Å; P164-M168 WeakPolarHBondContact O-CB 3.35Å; P164-M168 PolarHBondContact O-N 3Å; P164-Y210 HydrophobicContact CB-CD2 3.68Å; P164-Y210 HydrophobicContact CB-CE2 3.65Å; P164-I213 HydrophobicContact CB-CB 3.97Å; P164-I213 HydrophobicContact CB-CG2 3.64Å; P164-I213 HydrophobicContact CG-CG2 4.02Å; P164-V214 HydrophobicContact CB-CG2 3.66Å; P164-V214 HydrophobicContact CG-CB 4.27Å; P164-V214 HydrophobicContact CG-CG2 3.68Å; P164-F217 HydrophobicContact CG-CB 4.31Å
165	K	93.7	Very high	92	Very high	17 Å²	17	19.6 Å²	19.6	7%	0.074	10%	0.104	C	C	.	.	H	α-helix	trans	-63	-42.3	176.2	-172.5	165.4	-174.6	153	0	111.8	A161 V163 N169 Y210 D336 V337 L340 D461 V463	A161-K165 WeakPolarHBondContact O-CB 3.47Å; A161-K165 PolarHBondContact O-N 3.04Å; V163-K165 PolarHBondContact O-N 3.15Å; K165-N169 PolarHBondContact O-N 2.8Å; K165-N169 VanDerWaalsContact O-N 3.1Å; K165-N169 PolarHBondContact O-ND2 2.91Å; K165-Y210 HydrophobicContact CB-CD2 4.33Å; K165-Y210 HydrophobicContact CB-CE2 4.13Å; K165-D336 WeakPolarHBondContact CE-OD1 3.46Å; K165-D336 VanDerWaalsContact NZ-CG 3.26Å; K165-D336 IonicContact NZ-OD1 3.36Å; K165-D336 PolarHBondContact NZ-OD1 3.46Å; K165-D336 VanDerWaalsContact NZ-OD1 3.12Å; K165-D336 IonicContact NZ-OD2 3.59Å; K165-D336 PolarHBondContact NZ-OD2 3.43Å; K165-V337 HydrophobicContact CD-CG2 4.45Å; K165-L340 HydrophobicContact CD-CD1 4.46Å; K165-L340 HydrophobicContact CG-CD1 4.16Å; K165-D461 HydrophobicContact CD-CB 4.39Å; K165-D461 WeakPolarHBondContact CD-O 3.28Å; K165-D461 WeakPolarHBondContact CE-OD2 3.41Å; K165-D461 PolarHBondContact NZ-O 3.29Å; K165-D461 IonicContact NZ-OD2 3.88Å; K165-D461 PolarHBondContact NZ-OD2 3.44Å; K165-V463 HydrophobicContact CD-CG2 4.33Å
166	S	93.7	Very high	91.1	Very high	0 Å²	0	19.9 Å²	19.9	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-64	-45.9	175.7	-57.7	0	0	0	0	111.9	V162 V163 P164 N169 A170 V364	V162-S166 VanDerWaalsContact O-CB 3.32Å; V162-S166 WeakPolarHBondContact O-CB 3.26Å; V162-S166 PolarHBondContact O-N 2.87Å; V162-S166 PolarHBondContact O-OG 2.9Å; V163-S166 PolarHBondContact O-N 3.11Å; P164-S166 PolarHBondContact O-N 2.95Å; S166-N169 PolarHBondContact O-N 3.23Å; S166-A170 PolarHBondContact O-N 2.74Å; S166-A170 VanDerWaalsContact O-N 3.1Å; S166-V364 WeakPolarHBondContact CB-O 3.25Å; S166-V364 WeakPolarHBondContact O-CG2 3.43Å
167	L	93.9	Very high	89.8	Confident	50 Å²	50	24.2 Å²	24.2	26%	0.262	13%	0.13	S	C	.	.	H	α-helix	trans	-70	-38.4	-179.6	-172.8	62.3	0	0	0	112.5	V163 P164 N169 A170 I171 I213 L365 V368	V163-L167 PolarHBondContact O-N 3.05Å; P164-L167 PolarHBondContact O-N 2.98Å; L167-N169 VanDerWaalsContact C-N 3.35Å; L167-N169 PolarHBondContact O-N 2.96Å; L167-A170 PolarHBondContact O-N 3.42Å; L167-I171 HydrophobicContact CD1-CD1 3.86Å; L167-I171 HydrophobicContact CD1-CG1 4.28Å; L167-I171 HydrophobicContact CD2-CD1 4.33Å; L167-I171 HydrophobicContact CG-CD1 3.71Å; L167-I171 HydrophobicContact CG-CG1 4.46Å; L167-I171 WeakPolarHBondContact O-CG1 3.19Å; L167-I171 PolarHBondContact O-N 2.82Å; L167-I213 HydrophobicContact CB-CD1 4.18Å; L167-I213 HydrophobicContact CB-CG2 4.19Å; L167-I213 HydrophobicContact CD2-CD1 4.28Å; L167-I213 HydrophobicContact CD2-CG1 4.36Å; L167-I213 HydrophobicContact CD2-CG2 3.7Å; L167-I213 HydrophobicContact CG-CD1 4.07Å; L167-I213 HydrophobicContact CG-CG2 4.37Å; L167-L365 HydrophobicContact CD1-CD2 4.21Å; L167-V368 HydrophobicContact CB-CG2 4.46Å
168	M	93.4	Very high	88.4	Confident	2 Å²	2	28.2 Å²	28.2	1%	0.01	16%	0.157	C	C	.	.	H	α-helix	trans	-57.3	-49.2	173	177.5	-157.9	66.8	0	0	110.4	P164 A170 I171 C172 R206 V209 I213	P164-M168 VanDerWaalsContact O-CB 3.24Å; P164-M168 WeakPolarHBondContact O-CB 3.35Å; P164-M168 PolarHBondContact O-N 3Å; M168-A170 VanDerWaalsContact C-N 3.26Å; M168-A170 PolarHBondContact O-N 3.13Å; M168-I171 PolarHBondContact O-N 3.5Å; M168-I171 VanDerWaalsContact O-N 3.13Å; M168-C172 WeakPolarHBondContact O-CB 3.41Å; M168-C172 PolarHBondContact O-N 3.28Å; M168-C172 PolarHBondContact O-SG 3.38Å; M168-R206 VanDerWaalsContact SD-C 3.52Å; M168-R206 HydrophobicContact SD-CB 3.75Å; M168-V209 HydrophobicContact CG-CB 4.46Å; M168-V209 HydrophobicContact CG-CG1 4.14Å; M168-I213 HydrophobicContact CB-CD1 3.99Å
169	N	89.6	Confident	86.9	Confident	12 Å²	12	30.6 Å²	30.6	6%	0.064	17%	0.17	C	C	.	.	H	α-helix	trans	-61.7	-34.3	178.5	-84	-75.3	0	0	0	112.5	K165 S166 L167 R206 L340 F343	K165-N169 PolarHBondContact O-N 2.8Å; K165-N169 VanDerWaalsContact O-N 3.1Å; K165-N169 PolarHBondContact O-ND2 2.91Å; S166-N169 PolarHBondContact O-N 3.23Å; L167-N169 VanDerWaalsContact C-N 3.35Å; L167-N169 PolarHBondContact O-N 2.96Å; N169-R206 PolarHBondContact OD1-NH2 2.91Å; N169-L340 HydrophobicContact CB-CD2 3.76Å; N169-F343 WeakPolarHBondContact O-CE1 3.28Å
170	A	89.6	Confident	85.2	Confident	13 Å²	13	33.7 Å²	33.7	11%	0.107	19%	0.188	C	C	.	.	H	α-helix	trans	-71.2	-27	176.3	0	0	0	0	0	113.8	S166 L167 M168 V364	S166-A170 PolarHBondContact O-N 2.74Å; S166-A170 VanDerWaalsContact O-N 3.1Å; L167-A170 PolarHBondContact O-N 3.42Å; M168-A170 VanDerWaalsContact C-N 3.26Å; M168-A170 PolarHBondContact O-N 3.13Å; A170-V364 HydrophobicContact CB-CG1 3.85Å; A170-V364 HydrophobicContact CB-CG2 4.27Å
171	I	90.6	Very high	83.1	Confident	68 Å²	68	40.8 Å²	40.8	35%	0.349	23%	0.226	S	C	.	.	H	α-helix	trans	-98.2	-34.5	-174.6	-67.4	173	0	0	0	112.5	L167 M168 T173 W197 I213	L167-I171 HydrophobicContact CD1-CD1 3.86Å; L167-I171 HydrophobicContact CD1-CG1 4.28Å; L167-I171 HydrophobicContact CD2-CD1 4.33Å; L167-I171 HydrophobicContact CG-CD1 3.71Å; L167-I171 HydrophobicContact CG-CG1 4.46Å; L167-I171 WeakPolarHBondContact O-CG1 3.19Å; L167-I171 PolarHBondContact O-N 2.82Å; M168-I171 PolarHBondContact O-N 3.5Å; M168-I171 VanDerWaalsContact O-N 3.13Å; I171-T173 PolarHBondContact O-N 3.07Å; I171-W197 HydrophobicContact CG2-CH2 4.35Å; I171-W197 HydrophobicContact CG2-CZ2 3.49Å; I171-W197 VanDerWaalsContact CG2-CZ2 3.49Å; I171-W197 PolarHBondContact O-NE1 2.94Å; I171-W197 VanDerWaalsContact O-NE1 3.12Å; I171-I213 HydrophobicContact CD1-CD1 4.47Å
172	C	88.5	Confident	80.9	Confident	9 Å²	9	48.3 Å²	48.3	6%	0.061	26%	0.261	C	S	.	.			trans	-80.6	115.4	-178.3	-66.8	0	0	0	0	111.8	M168 C196 R206	M168-C172 WeakPolarHBondContact O-CB 3.41Å; M168-C172 PolarHBondContact O-N 3.28Å; M168-C172 PolarHBondContact O-SG 3.38Å; C172-C196 CarbonylContact C-O 3.28Å; C172-C196 WeakPolarHBondContact CA-O 3.37Å; C172-C196 WeakPolarHBondContact CA-SG 3.38Å; C172-C196 HydrophobicContact CB-CB 3.95Å; C172-C196 WeakPolarHBondContact CB-O 3.26Å; C172-C196 WeakPolarHBondContact CB-SG 3.47Å; C172-C196 WeakPolarHBondContact SG-CB 3.35Å; C172-C196 CovalentContact SG-SG 2.03Å; C172-C196 PolarHBondContact SG-SG 2.99Å; C172-R206 HydrophobicContact CB-CG 4.39Å; C172-R206 VanDerWaalsContact CB-NH1 3.26Å
173	T	83.1	Confident	78.6	Confident	100 Å²	100	49.3 Å²	49.3	61%	0.613	27%	0.267	S	S	*	.			trans	-101.6	-7.7	-173.4	65	0	0	0	0	114.5	I171 I175 C196	I171-T173 PolarHBondContact O-N 3.07Å; T173-I175 PolarHBondContact O-N 2.84Å; T173-C196 PolarHBondContact N-O 3.46Å
174	Y	80.7	Confident	76.3	Confident	51 Å²	51	53.2 Å²	53.2	20%	0.2	30%	0.295	C	S	.	.			trans	-72.5	127.2	-178	-179.4	-103.5	0	0	0	112.1	P176 L190 L194 P195 C196 K198	Y174-P176 HydrophobicContact CE1-CG 4.03Å; Y174-L190 WeakPolarHBondContact O-CD2 3.4Å; Y174-L194 HydrophobicContact CD1-CB 4.34Å; Y174-L194 HydrophobicContact CE1-CB 4.47Å; Y174-L194 HydrophobicContact CE1-CD2 4.33Å; Y174-P195 VanDerWaalsContact CB-O 3.28Å; Y174-P195 WeakPolarHBondContact CB-O 3.29Å; Y174-P195 HydrophobicContact CD1-CG 3.62Å; Y174-P195 VanDerWaalsContact CD1-O 3.32Å; Y174-P195 WeakPolarHBondContact CD1-O 3.48Å; Y174-P195 HydrophobicContact CD2-CG 4.41Å; Y174-P195 HydrophobicContact CE1-CG 3.58Å; Y174-P195 HydrophobicContact CE2-CG 4.39Å; Y174-P195 HydrophobicContact CG-CG 4.04Å; Y174-C196 WeakPolarHBondContact CB-O 3.15Å; Y174-C196 PolarHBondContact N-O 3.41Å; Y174-K198 HydrophobicContact CD2-CB 3.85Å; Y174-K198 HydrophobicContact CD2-CG 4.18Å; Y174-K198 HydrophobicContact CE2-CB 4.4Å; Y174-K198 HydrophobicContact CE2-CG 4.23Å
175	I	76.6	Confident	74.1	Confident	54 Å²	54	55.3 Å²	55.3	28%	0.277	32%	0.316	S	S	.	.			trans	-127.3	129.2	170.3	-60.3	172.9	0	0	0	106.6	T173 L179	T173-I175 PolarHBondContact O-N 2.84Å; I175-L179 HydrophobicContact CG2-CB 4.37Å
176	P	75.2	Confident	72.2	Confident	15 Å²	15	59 Å²	59	10%	0.097	33%	0.332	C	S	.	.			trans	-62.7	137.3	178	-19.8	30.8	0	0	0	112	Y174 S178 L179 D180 L194	Y174-P176 HydrophobicContact CE1-CG 4.03Å; P176-S178 PolarHBondContact O-N 3.39Å; P176-L179 HydrophobicContact CB-CD1 3.97Å; P176-L179 HydrophobicContact CG-CD1 3.98Å; P176-L179 PolarHBondContact O-N 3.5Å; P176-D180 PolarHBondContact O-N 2.95Å; P176-L194 HydrophobicContact CG-CD1 3.77Å; P176-L194 HydrophobicContact CG-CD2 4.03Å
177	D	69.6	Low	70.5	Confident	92 Å²	92	59.7 Å²	59.7	49%	0.492	34%	0.337	S	S	.	.	H	α-helix	trans	-57.6	-23.8	-179.2	-58.9	-17.5	0	0	0	112.7	L179 D180 K198	D177-L179 VanDerWaalsContact C-N 3.32Å; D177-L179 PolarHBondContact O-N 3.07Å; D177-D180 PolarHBondContact O-N 3.06Å; D177-K198 IonicContact OD1-NZ 3.34Å; D177-K198 PolarHBondContact OD1-NZ 3.36Å; D177-K198 IonicContact OD2-NZ 3.76Å
178	S	67.7	Low	68.9	Low	84 Å²	84	58 Å²	58	59%	0.587	33%	0.329	S	S	*	.	H	α-helix	trans	-68.8	-27.4	174.7	58.5	0	0	0	0	113.8	P176	P176-S178 PolarHBondContact O-N 3.39Å
179	L	65.3	Low	67.8	Low	50 Å²	50	62.7 Å²	62.7	26%	0.262	35%	0.354	S	S	.	.	H	α-helix	trans	-89.5	-29.8	174	-75	97.2	0	0	0	111.5	I175 P176 D177 N181 Q182 T183 P188	I175-L179 HydrophobicContact CG2-CB 4.37Å; P176-L179 HydrophobicContact CB-CD1 3.97Å; P176-L179 HydrophobicContact CG-CD1 3.98Å; P176-L179 PolarHBondContact O-N 3.5Å; D177-L179 VanDerWaalsContact C-N 3.32Å; D177-L179 PolarHBondContact O-N 3.07Å; L179-N181 VanDerWaalsContact C-N 3.29Å; L179-N181 PolarHBondContact O-N 3.38Å; L179-Q182 PolarHBondContact O-N 3.32Å; L179-T183 HydrophobicContact CB-CG2 4.25Å; L179-T183 VanDerWaalsContact O-CB 3.26Å; L179-T183 WeakPolarHBondContact O-CB 3.39Å; L179-T183 WeakPolarHBondContact O-CG2 3.46Å; L179-T183 PolarHBondContact O-N 3.05Å; L179-T183 PolarHBondContact O-OG1 2.9Å; L179-P188 HydrophobicContact CB-CB 4.39Å; L179-P188 HydrophobicContact CD2-CB 3.27Å; L179-P188 HydrophobicContact CG-CB 4.43Å
180	D	60.1	Low	67.2	Low	84 Å²	84	63 Å²	63	45%	0.449	36%	0.356	S	S	.	.	H	α-helix	trans	-56.8	-41.2	178.4	-162.6	22.9	0	0	0	112.1	P176 D177 T183	P176-D180 PolarHBondContact O-N 2.95Å; D177-D180 PolarHBondContact O-N 3.06Å; D180-T183 PolarHBondContact O-OG1 3.31Å
181	N	51.4	Low	66.8	Low	148 Å²	148	65.3 Å²	65.3	79%	0.791	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.1	-13.6	-179.6	-79.5	-33.9	0	0	0	115.8	L179	L179-N181 VanDerWaalsContact C-N 3.29Å; L179-N181 PolarHBondContact O-N 3.38Å
182	Q	49.3	Very low	66.4	Low	159 Å²	159	64.3 Å²	64.3	74%	0.743	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.9	-5.2	-178.2	-65.8	-169.8	19.8	0	0	113.9	L179 S184	L179-Q182 PolarHBondContact O-N 3.32Å; Q182-S184 PolarHBondContact O-N 2.95Å
183	T	48.5	Very low	66.2	Low	23 Å²	23	70 Å²	70	14%	0.141	40%	0.396	C	S	.	.			trans	-99.6	36.2	-168.3	48.5	0	0	0	0	114.1	L179 D180 G185 P188	L179-T183 HydrophobicContact CB-CG2 4.25Å; L179-T183 VanDerWaalsContact O-CB 3.26Å; L179-T183 WeakPolarHBondContact O-CB 3.39Å; L179-T183 WeakPolarHBondContact O-CG2 3.46Å; L179-T183 PolarHBondContact O-N 3.05Å; L179-T183 PolarHBondContact O-OG1 2.9Å; D180-T183 PolarHBondContact O-OG1 3.31Å; T183-G185 PolarHBondContact O-N 2.89Å; T183-P188 HydrophobicContact CG2-CB 4.21Å
184	S	46.1	Very low	66.4	Low	87 Å²	87	67.1 Å²	67.1	61%	0.608	38%	0.377	S	S	*	.	S	Bend	trans	-68.2	78.8	163	59.3	0	0	0	0	110.4	Q182 K348	Q182-S184 PolarHBondContact O-N 2.95Å; S184-K348 VanDerWaalsContact CB-NZ 3.32Å
185	G	49.9	Very low	66.7	Low	43 Å²	43	66.3 Å²	66.3	44%	0.443	38%	0.378	S	S	.	.	S	Bend	trans	106.8	13.5	172.1	0	0	0	0	0	116.7	T183 R257	T183-G185 PolarHBondContact O-N 2.89Å; G185-R257 PolarHBondContact O-NH2 3.23Å
186	F	54.6	Low	67.3	Low	96 Å²	96	63.8 Å²	63.8	42%	0.421	37%	0.365	S	S	.	.			trans	-123.8	133.9	175.7	-68.7	-75.8	0	0	0	111.7	P188 R332	F186-P188 VanDerWaalsContact O-CD 3.25Å; F186-P188 WeakPolarHBondContact O-CD 3.31Å; F186-R332 HydrophobicContact CD1-CB 3.65Å; F186-R332 HydrophobicContact CD1-CG 4.39Å; F186-R332 HydrophobicContact CE1-CB 3.74Å; F186-R332 HydrophobicContact CE1-CG 4.34Å
187	S	56.2	Low	67.9	Low	14 Å²	14	67.7 Å²	67.7	10%	0.098	38%	0.378	C	S	.	.			trans	-66.8	112.8	171.1	-60.8	0	0	0	0	108.2	N189 N341	S187-N189 PolarHBondContact O-N 3.41Å; S187-N341 PolarHBondContact OG-O 3.02Å
188	P	61.9	Low	68.3	Low	14 Å²	14	70.4 Å²	70.4	9%	0.091	39%	0.385	C	S	.	.			trans	-66.3	131.4	-179.7	25.3	-33.4	0	0	0	110.6	L179 T183 F186 L190 Q344	L179-P188 HydrophobicContact CB-CB 4.39Å; L179-P188 HydrophobicContact CD2-CB 3.27Å; L179-P188 HydrophobicContact CG-CB 4.43Å; T183-P188 HydrophobicContact CG2-CB 4.21Å; F186-P188 VanDerWaalsContact O-CD 3.25Å; F186-P188 WeakPolarHBondContact O-CD 3.31Å; P188-L190 HydrophobicContact CB-CD1 3.69Å; P188-L190 HydrophobicContact CG-CD1 3.52Å; P188-L190 WeakPolarHBondContact O-CD1 3.2Å; P188-L190 PolarHBondContact O-N 2.89Å; P188-Q344 PolarHBondContact O-OE1 2.87Å
189	N	69.9	Low	68.5	Low	100 Å²	100	68.8 Å²	68.8	54%	0.535	37%	0.374	S	S	.	.			trans	-76.3	101.5	166.6	-178.2	-12.2	0	0	0	107.8	S187 H333	S187-N189 PolarHBondContact O-N 3.41Å; N189-H333 PolarHBondContact ND2-NE2 3.3Å
190	L	77.5	Confident	68.6	Low	20 Å²	20	76.3 Å²	76.3	11%	0.105	41%	0.407	C	S	.	.			trans	-88.5	124.2	178.4	-82.9	86.2	0	0	0	110.2	Y174 P188 L194	Y174-L190 WeakPolarHBondContact O-CD2 3.4Å; P188-L190 HydrophobicContact CB-CD1 3.69Å; P188-L190 HydrophobicContact CG-CD1 3.52Å; P188-L190 WeakPolarHBondContact O-CD1 3.2Å; P188-L190 PolarHBondContact O-N 2.89Å; L190-L194 HydrophobicContact CB-CD1 4.15Å; L190-L194 HydrophobicContact CD2-CD1 4.32Å; L190-L194 HydrophobicContact CG-CD1 4.18Å
191	S	81.3	Confident	69	Low	60 Å²	60	77 Å²	77	42%	0.42	42%	0.419	S	S	.	.			trans	-68.7	140.4	170.9	178.2	0	0	0	0	111.7	N193 L194	S191-N193 PolarHBondContact O-N 3.21Å; S191-N193 PolarHBondContact OG-N 2.97Å; S191-L194 VanDerWaalsContact O-CB 3.29Å; S191-L194 WeakPolarHBondContact O-CB 3.34Å; S191-L194 VanDerWaalsContact O-CG 3.27Å; S191-L194 WeakPolarHBondContact O-CG 3.45Å; S191-L194 PolarHBondContact O-N 2.86Å; S191-L194 VanDerWaalsContact O-N 3.08Å
192	D	81.4	Confident	69.9	Low	47 Å²	47	73.4 Å²	73.4	25%	0.251	40%	0.402	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.3	-13.2	178.8	-54	-56.1	0	0	0	114.2	L194 R206 F207	D192-L194 VanDerWaalsContact C-N 3.25Å; D192-R206 PolarHBondContact O-N 2.95Å; D192-F207 HydrophobicContact CB-CB 4.04Å; D192-F207 PolarHBondContact O-N 3.47Å; D192-F207 VanDerWaalsContact O-N 3.1Å
193	N	85.1	Confident	71.3	Confident	128 Å²	128	72.4 Å²	72.4	68%	0.684	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78.6	-9.6	173.9	-65.6	-36.8	0	0	0	112.8	S191	S191-N193 PolarHBondContact O-N 3.21Å; S191-N193 PolarHBondContact OG-N 2.97Å
194	L	86.4	Confident	73.2	Confident	41 Å²	41	74.6 Å²	74.6	22%	0.215	41%	0.412	C	S	.	.	S	Bend	trans	-68.1	151	175.4	-66.1	172.7	0	0	0	110.8	Y174 P176 L190 S191 D192 T205 R206	Y174-L194 HydrophobicContact CD1-CB 4.34Å; Y174-L194 HydrophobicContact CE1-CB 4.47Å; Y174-L194 HydrophobicContact CE1-CD2 4.33Å; P176-L194 HydrophobicContact CG-CD1 3.77Å; P176-L194 HydrophobicContact CG-CD2 4.03Å; L190-L194 HydrophobicContact CB-CD1 4.15Å; L190-L194 HydrophobicContact CD2-CD1 4.32Å; L190-L194 HydrophobicContact CG-CD1 4.18Å; S191-L194 VanDerWaalsContact O-CB 3.29Å; S191-L194 WeakPolarHBondContact O-CB 3.34Å; S191-L194 VanDerWaalsContact O-CG 3.27Å; S191-L194 WeakPolarHBondContact O-CG 3.45Å; S191-L194 PolarHBondContact O-N 2.86Å; S191-L194 VanDerWaalsContact O-N 3.08Å; D192-L194 VanDerWaalsContact C-N 3.25Å; L194-T205 CarbonylContact O-C 3.42Å; L194-T205 WeakPolarHBondContact O-CA 3.49Å; L194-R206 WeakPolarHBondContact O-CG 3.47Å; L194-R206 PolarHBondContact O-N 3.49Å
195	P	88	Confident	75.4	Confident	34 Å²	34	72.1 Å²	72.1	22%	0.221	39%	0.393	C	S	.	.	B	Isolated β-bridge	trans	-62.7	149.4	171.1	26.3	-32.1	0	0	0	110.4	Y174	Y174-P195 VanDerWaalsContact CB-O 3.28Å; Y174-P195 WeakPolarHBondContact CB-O 3.29Å; Y174-P195 HydrophobicContact CD1-CG 3.62Å; Y174-P195 VanDerWaalsContact CD1-O 3.32Å; Y174-P195 WeakPolarHBondContact CD1-O 3.48Å; Y174-P195 HydrophobicContact CD2-CG 4.41Å; Y174-P195 HydrophobicContact CE1-CG 3.58Å; Y174-P195 HydrophobicContact CE2-CG 4.39Å; Y174-P195 HydrophobicContact CG-CG 4.04Å
196	C	87.5	Confident	77.4	Confident	0 Å²	0	70.4 Å²	70.4	0%	0	37%	0.373	C	S	.	.	S	Bend	trans	-76	-32.9	179.9	179.9	0	0	0	0	112.5	C172 T173 Y174 I204 R206 V209	C172-C196 CarbonylContact C-O 3.28Å; C172-C196 WeakPolarHBondContact CA-O 3.37Å; C172-C196 WeakPolarHBondContact CA-SG 3.38Å; C172-C196 HydrophobicContact CB-CB 3.95Å; C172-C196 WeakPolarHBondContact CB-O 3.26Å; C172-C196 WeakPolarHBondContact CB-SG 3.47Å; C172-C196 WeakPolarHBondContact SG-CB 3.35Å; C172-C196 CovalentContact SG-SG 2.03Å; C172-C196 PolarHBondContact SG-SG 2.99Å; T173-C196 PolarHBondContact N-O 3.46Å; Y174-C196 WeakPolarHBondContact CB-O 3.15Å; Y174-C196 PolarHBondContact N-O 3.41Å; C196-I204 PolarHBondContact N-O 3.43Å; C196-R206 HydrophobicContact CB-CG 4.46Å; C196-V209 HydrophobicContact CB-CG2 3.86Å
197	W	88.1	Confident	79.2	Confident	98 Å²	98	67.5 Å²	67.5	37%	0.371	36%	0.361	S	S	.	.	S	Bend	trans	-131.1	151.9	179.5	-59.9	-79.2	0	0	0	111.6	I171 S199 V209	I171-W197 HydrophobicContact CG2-CH2 4.35Å; I171-W197 HydrophobicContact CG2-CZ2 3.49Å; I171-W197 VanDerWaalsContact CG2-CZ2 3.49Å; I171-W197 PolarHBondContact O-NE1 2.94Å; I171-W197 VanDerWaalsContact O-NE1 3.12Å; W197-S199 VanDerWaalsContact C-N 3.31Å; W197-S199 PolarHBondContact O-N 3.34Å; W197-V209 HydrophobicContact CH2-CG2 3.95Å; W197-V209 HydrophobicContact CZ3-CG2 3.86Å
198	K	78.7	Confident	81.1	Confident	148 Å²	148	70.2 Å²	70.2	64%	0.643	37%	0.374	S	S	*	.			trans	-74.5	83.8	171	-160.2	165.6	-175.3	161.5	0	108.2	Y174 D177	Y174-K198 HydrophobicContact CD2-CB 3.85Å; Y174-K198 HydrophobicContact CD2-CG 4.18Å; Y174-K198 HydrophobicContact CE2-CB 4.4Å; Y174-K198 HydrophobicContact CE2-CG 4.23Å; D177-K198 IonicContact OD1-NZ 3.34Å; D177-K198 PolarHBondContact OD1-NZ 3.36Å; D177-K198 IonicContact OD2-NZ 3.76Å
199	S	72.5	Confident	82.6	Confident	51 Å²	51	70.2 Å²	70.2	36%	0.357	37%	0.374	S	S	.	.			trans	-138.4	130.1	175.7	-174.3	0	0	0	0	110.5	W197 S201	W197-S199 VanDerWaalsContact C-N 3.31Å; W197-S199 PolarHBondContact O-N 3.34Å; S199-S201 PolarHBondContact O-N 2.97Å; S199-S201 PolarHBondContact OG-N 3.28Å; S199-S201 PolarHBondContact OG-OG 3.16Å; S199-S201 VanDerWaalsContact OG-OG 3.04Å
200	E	65.7	Low	83.9	Confident	207 Å²	207	65.5 Å²	65.5	97%	0.967	35%	0.348	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.3	-10.1	175.8	-65.6	179.2	170.5	0	0	113.3
201	S	69.2	Low	84.8	Confident	100 Å²	100	67.6 Å²	67.6	70%	0.699	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-107.4	-13.6	-170.6	63.4	0	0	0	0	115.1	S199	S199-S201 PolarHBondContact O-N 2.97Å; S199-S201 PolarHBondContact OG-N 3.28Å; S199-S201 PolarHBondContact OG-OG 3.16Å; S199-S201 VanDerWaalsContact OG-OG 3.04Å
202	V	70.5	Confident	85.5	Confident	71 Å²	71	68.7 Å²	68.7	43%	0.43	36%	0.359	S	S	.	.			trans	-144.8	95.3	-172.5	-179	0	0	0	0	110.6	I204	V202-I204 HydrophobicContact CG1-CB 4.23Å; V202-I204 HydrophobicContact CG1-CD1 3.38Å; V202-I204 HydrophobicContact CG1-CG1 3.45Å; V202-I204 VanDerWaalsContact CG1-CG1 3.45Å; V202-I204 PolarHBondContact O-N 3.01Å
203	D	79	Confident	86.2	Confident	139 Å²	139	67.2 Å²	67.2	74%	0.743	35%	0.351	S	S	*	.			trans	-82.4	58.4	175.4	-71.1	-27.9	0	0	0	111.8	T205	D203-T205 PolarHBondContact O-N 3.46Å
204	I	88.8	Confident	86.8	Confident	68 Å²	68	61.2 Å²	61.2	35%	0.349	32%	0.319	S	S	.	.			trans	-85.2	115.6	170.7	-60.9	167.7	0	0	0	108.5	C196 V202 N208 V209	C196-I204 PolarHBondContact N-O 3.43Å; V202-I204 HydrophobicContact CG1-CB 4.23Å; V202-I204 HydrophobicContact CG1-CD1 3.38Å; V202-I204 HydrophobicContact CG1-CG1 3.45Å; V202-I204 VanDerWaalsContact CG1-CG1 3.45Å; V202-I204 PolarHBondContact O-N 3.01Å; I204-N208 HydrophobicContact CG2-CB 3.8Å; I204-V209 HydrophobicContact CG2-CG2 3.64Å
205	T	91.9	Very high	87.3	Confident	35 Å²	35	62.3 Å²	62.3	22%	0.215	33%	0.328	C	S	.	.	B	Isolated β-bridge	trans	-65.2	154	175.5	64.3	0	0	0	0	111.7	L194 D203 F207 N208 V209	L194-T205 CarbonylContact O-C 3.42Å; L194-T205 WeakPolarHBondContact O-CA 3.49Å; D203-T205 PolarHBondContact O-N 3.46Å; T205-F207 PolarHBondContact O-N 3.25Å; T205-N208 PolarHBondContact O-N 3.14Å; T205-N208 VanDerWaalsContact O-N 3.09Å; T205-N208 WeakPolarHBondContact OG1-CB 3.49Å; T205-N208 VanDerWaalsContact OG1-CG 3.27Å; T205-N208 PolarHBondContact OG1-N 2.97Å; T205-N208 PolarHBondContact OG1-ND2 3.42Å; T205-V209 PolarHBondContact O-N 3.45Å; T205-V209 VanDerWaalsContact O-N 3.12Å
206	R	91.9	Very high	87.7	Confident	7 Å²	7	65.3 Å²	65.3	3%	0.026	34%	0.34	C	S	.	.	H	α-helix	trans	-52.6	-45.7	173.1	-67.7	174.2	75.3	83.8	3	110.6	M168 N169 C172 D192 L194 C196 N208 V209 Y210	M168-R206 VanDerWaalsContact SD-C 3.52Å; M168-R206 HydrophobicContact SD-CB 3.75Å; N169-R206 PolarHBondContact OD1-NH2 2.91Å; C172-R206 HydrophobicContact CB-CG 4.39Å; C172-R206 VanDerWaalsContact CB-NH1 3.26Å; D192-R206 PolarHBondContact O-N 2.95Å; L194-R206 WeakPolarHBondContact O-CG 3.47Å; L194-R206 PolarHBondContact O-N 3.49Å; C196-R206 HydrophobicContact CB-CG 4.46Å; R206-N208 VanDerWaalsContact C-N 3.32Å; R206-N208 PolarHBondContact O-N 2.97Å; R206-V209 WeakPolarHBondContact O-CB 3.5Å; R206-V209 PolarHBondContact O-N 3.33Å; R206-V209 VanDerWaalsContact O-N 3.11Å; R206-Y210 PolarHBondContact O-N 2.87Å
207	F	93	Very high	88	Confident	36 Å²	36	66 Å²	66	16%	0.158	34%	0.343	C	S	.	.	H	α-helix	trans	-61.1	-35.3	178.2	-164.3	-125.2	0	0	0	114.3	D192 T205 Y210 R211 D461	D192-F207 HydrophobicContact CB-CB 4.04Å; D192-F207 PolarHBondContact O-N 3.47Å; D192-F207 VanDerWaalsContact O-N 3.1Å; T205-F207 PolarHBondContact O-N 3.25Å; F207-Y210 AromaticContact CD2-CD1 3.92Å; F207-Y210 HydrophobicContact CD2-CD1 3.92Å; F207-Y210 AromaticContact CE2-CD1 3.87Å; F207-Y210 HydrophobicContact CE2-CD1 3.87Å; F207-Y210 HydrophobicContact CE2-CE1 4.06Å; F207-Y210 WeakPolarHBondContact O-CB 3.3Å; F207-Y210 PolarHBondContact O-N 2.95Å; F207-R211 VanDerWaalsContact CE1-NE 3.34Å; F207-R211 WeakPolarHBondContact O-CG 3.46Å; F207-R211 PolarHBondContact O-N 3.47Å; F207-D461 HydrophobicContact CE2-CB 4.32Å
208	N	94.3	Very high	88.3	Confident	70 Å²	70	61.9 Å²	61.9	37%	0.374	33%	0.331	S	S	.	.	H	α-helix	trans	-70.1	-38.3	175.3	-76.4	-19.3	0	0	0	111.7	I204 T205 R206 R211 V212	I204-N208 HydrophobicContact CG2-CB 3.8Å; T205-N208 PolarHBondContact O-N 3.14Å; T205-N208 VanDerWaalsContact O-N 3.09Å; T205-N208 WeakPolarHBondContact OG1-CB 3.49Å; T205-N208 VanDerWaalsContact OG1-CG 3.27Å; T205-N208 PolarHBondContact OG1-N 2.97Å; T205-N208 PolarHBondContact OG1-ND2 3.42Å; R206-N208 VanDerWaalsContact C-N 3.32Å; R206-N208 PolarHBondContact O-N 2.97Å; N208-R211 PolarHBondContact O-N 3.3Å; N208-V212 WeakPolarHBondContact O-CG2 3.35Å; N208-V212 PolarHBondContact O-N 3.43Å
209	V	94.6	Very high	89	Confident	14 Å²	14	60 Å²	60	9%	0.085	33%	0.326	C	S	.	.	H	α-helix	trans	-62.8	-43.8	172	168.6	0	0	0	0	110.7	M168 C196 W197 I204 T205 R206 R211 V212 I213	M168-V209 HydrophobicContact CG-CB 4.46Å; M168-V209 HydrophobicContact CG-CG1 4.14Å; C196-V209 HydrophobicContact CB-CG2 3.86Å; W197-V209 HydrophobicContact CH2-CG2 3.95Å; W197-V209 HydrophobicContact CZ3-CG2 3.86Å; I204-V209 HydrophobicContact CG2-CG2 3.64Å; T205-V209 PolarHBondContact O-N 3.45Å; T205-V209 VanDerWaalsContact O-N 3.12Å; R206-V209 WeakPolarHBondContact O-CB 3.5Å; R206-V209 PolarHBondContact O-N 3.33Å; R206-V209 VanDerWaalsContact O-N 3.11Å; V209-R211 PolarHBondContact O-N 3.39Å; V209-V212 WeakPolarHBondContact O-CB 3.46Å; V209-V212 PolarHBondContact O-N 2.88Å; V209-I213 HydrophobicContact CG1-CD1 3.83Å; V209-I213 HydrophobicContact CG1-CG1 4.46Å; V209-I213 WeakPolarHBondContact O-CG1 3.23Å; V209-I213 PolarHBondContact O-N 3.42Å
210	Y	96.1	Very high	90	Very high	1 Å²	1	62.1 Å²	62.1	0%	0.004	34%	0.336	C	S	.	.	H	α-helix	trans	-52.8	-50.9	172.8	165.4	-99.5	0	0	0	111.8	A161 P164 K165 R206 F207 V212 I213 V214 A457 T460 D461	A161-Y210 WeakPolarHBondContact CA-OH 3.49Å; P164-Y210 HydrophobicContact CB-CD2 3.68Å; P164-Y210 HydrophobicContact CB-CE2 3.65Å; K165-Y210 HydrophobicContact CB-CD2 4.33Å; K165-Y210 HydrophobicContact CB-CE2 4.13Å; R206-Y210 PolarHBondContact O-N 2.87Å; F207-Y210 AromaticContact CD2-CD1 3.92Å; F207-Y210 HydrophobicContact CD2-CD1 3.92Å; F207-Y210 AromaticContact CE2-CD1 3.87Å; F207-Y210 HydrophobicContact CE2-CD1 3.87Å; F207-Y210 HydrophobicContact CE2-CE1 4.06Å; F207-Y210 WeakPolarHBondContact O-CB 3.3Å; F207-Y210 PolarHBondContact O-N 2.95Å; Y210-V212 VanDerWaalsContact C-N 3.35Å; Y210-V212 PolarHBondContact O-N 3.31Å; Y210-I213 CarbonylContact O-C 3.54Å; Y210-I213 WeakPolarHBondContact O-CA 3.31Å; Y210-I213 WeakPolarHBondContact O-CB 3.47Å; Y210-I213 PolarHBondContact O-N 2.66Å; Y210-V214 HydrophobicContact CD1-CG2 4.22Å; Y210-V214 HydrophobicContact CD2-CG2 4.36Å; Y210-V214 HydrophobicContact CE1-CG2 3.82Å; Y210-V214 HydrophobicContact CE2-CG2 3.98Å; Y210-V214 HydrophobicContact CG-CG2 4.46Å; Y210-V214 WeakPolarHBondContact O-CG2 3.41Å; Y210-V214 PolarHBondContact O-N 3.05Å; Y210-A457 WeakPolarHBondContact CE1-O 3.33Å; Y210-A457 VanDerWaalsContact CZ-O 3.23Å; Y210-A457 PolarHBondContact OH-O 3.01Å; Y210-T460 PolarHBondContact OH-O 3.37Å; Y210-D461 HydrophobicContact CD1-CB 4.33Å; Y210-D461 HydrophobicContact CD2-CB 4.42Å; Y210-D461 HydrophobicContact CE1-CB 3.84Å; Y210-D461 HydrophobicContact CE2-CB 3.94Å
211	R	96.6	Very high	91.2	Very high	64 Å²	64	53.3 Å²	53.3	24%	0.242	30%	0.296	C	S	.	.	H	α-helix	trans	-60.4	-38.7	177.6	-77.7	173.1	167.7	175.5	-4	114	F207 N208 V209 I213 V214 T215 F458	F207-R211 VanDerWaalsContact CE1-NE 3.34Å; F207-R211 WeakPolarHBondContact O-CG 3.46Å; F207-R211 PolarHBondContact O-N 3.47Å; N208-R211 PolarHBondContact O-N 3.3Å; V209-R211 PolarHBondContact O-N 3.39Å; R211-I213 VanDerWaalsContact C-N 3.32Å; R211-V214 PolarHBondContact O-N 3.5Å; R211-T215 PolarHBondContact O-N 3.41Å; R211-T215 VanDerWaalsContact O-N 3.07Å; R211-T215 PolarHBondContact O-OG1 2.9Å; R211-F458 HydrophobicContact CB-CD2 4.06Å; R211-F458 HydrophobicContact CB-CE2 3.61Å; R211-F458 HydrophobicContact CB-CZ 4.02Å; R211-F458 HydrophobicContact CG-CD1 4.41Å; R211-F458 HydrophobicContact CG-CD2 3.96Å; R211-F458 HydrophobicContact CG-CE1 4.26Å; R211-F458 HydrophobicContact CG-CE2 3.81Å; R211-F458 HydrophobicContact CG-CG 4.27Å; R211-F458 HydrophobicContact CG-CZ 3.96Å; R211-F458 PolarHBondContact NE-O 3.43Å
212	V	96.2	Very high	92.2	Very high	83 Å²	83	48.6 Å²	48.6	50%	0.503	26%	0.263	S	S	.	.	H	α-helix	trans	-61	-45.7	172.4	172.2	0	0	0	0	109.8	N208 V209 Y210 T215 M216	N208-V212 WeakPolarHBondContact O-CG2 3.35Å; N208-V212 PolarHBondContact O-N 3.43Å; V209-V212 WeakPolarHBondContact O-CB 3.46Å; V209-V212 PolarHBondContact O-N 2.88Å; Y210-V212 VanDerWaalsContact C-N 3.35Å; Y210-V212 PolarHBondContact O-N 3.31Å; V212-T215 WeakPolarHBondContact O-CB 3.23Å; V212-T215 PolarHBondContact O-N 2.99Å; V212-M216 HydrophobicContact CG1-CE 4.29Å; V212-M216 HydrophobicContact CG1-CG 4.45Å; V212-M216 WeakPolarHBondContact O-CG 3.4Å; V212-M216 PolarHBondContact O-N 3.2Å
213	I	96.6	Very high	93.1	Very high	16 Å²	16	47.7 Å²	47.7	8%	0.082	26%	0.259	C	S	.	.	H	α-helix	trans	-65.7	-39.7	178.5	-62.3	165	0	0	0	111.8	P164 L167 M168 I171 V209 Y210 R211 T215 M216 F217	P164-I213 HydrophobicContact CB-CB 3.97Å; P164-I213 HydrophobicContact CB-CG2 3.64Å; P164-I213 HydrophobicContact CG-CG2 4.02Å; L167-I213 HydrophobicContact CB-CD1 4.18Å; L167-I213 HydrophobicContact CB-CG2 4.19Å; L167-I213 HydrophobicContact CD2-CD1 4.28Å; L167-I213 HydrophobicContact CD2-CG1 4.36Å; L167-I213 HydrophobicContact CD2-CG2 3.7Å; L167-I213 HydrophobicContact CG-CD1 4.07Å; L167-I213 HydrophobicContact CG-CG2 4.37Å; M168-I213 HydrophobicContact CB-CD1 3.99Å; I171-I213 HydrophobicContact CD1-CD1 4.47Å; V209-I213 HydrophobicContact CG1-CD1 3.83Å; V209-I213 HydrophobicContact CG1-CG1 4.46Å; V209-I213 WeakPolarHBondContact O-CG1 3.23Å; V209-I213 PolarHBondContact O-N 3.42Å; Y210-I213 CarbonylContact O-C 3.54Å; Y210-I213 WeakPolarHBondContact O-CA 3.31Å; Y210-I213 WeakPolarHBondContact O-CB 3.47Å; Y210-I213 PolarHBondContact O-N 2.66Å; R211-I213 VanDerWaalsContact C-N 3.32Å; I213-T215 VanDerWaalsContact C-N 3.25Å; I213-T215 PolarHBondContact O-N 2.85Å; I213-M216 PolarHBondContact O-N 3.45Å; I213-F217 VanDerWaalsContact O-CB 3.28Å; I213-F217 WeakPolarHBondContact O-CB 3.43Å; I213-F217 PolarHBondContact O-N 3.23Å
214	V	97.2	Very high	93.5	Very high	2 Å²	2	45.1 Å²	45.1	1%	0.012	24%	0.241	C	C	.	.	H	α-helix	trans	-55.3	-44.3	172.8	174.1	0	0	0	0	110.4	P164 Y210 R211 F217 G218 L454 A457 F458	P164-V214 HydrophobicContact CB-CG2 3.66Å; P164-V214 HydrophobicContact CG-CB 4.27Å; P164-V214 HydrophobicContact CG-CG2 3.68Å; Y210-V214 HydrophobicContact CD1-CG2 4.22Å; Y210-V214 HydrophobicContact CD2-CG2 4.36Å; Y210-V214 HydrophobicContact CE1-CG2 3.82Å; Y210-V214 HydrophobicContact CE2-CG2 3.98Å; Y210-V214 HydrophobicContact CG-CG2 4.46Å; Y210-V214 WeakPolarHBondContact O-CG2 3.41Å; Y210-V214 PolarHBondContact O-N 3.05Å; R211-V214 PolarHBondContact O-N 3.5Å; V214-F217 PolarHBondContact O-N 3.42Å; V214-G218 PolarHBondContact O-N 2.98Å; V214-L454 HydrophobicContact CG1-CB 4.48Å; V214-L454 HydrophobicContact CG1-CD2 4.2Å; V214-A457 HydrophobicContact CG1-CB 4.31Å; V214-F458 HydrophobicContact CG1-CB 4.5Å
215	T	96.4	Very high	93.4	Very high	65 Å²	65	41.9 Å²	41.9	40%	0.399	22%	0.224	S	C	.	.	H	α-helix	trans	-64.5	-45.1	178	-51.8	0	0	0	0	111.2	R211 V212 I213 G218 M219	R211-T215 PolarHBondContact O-N 3.41Å; R211-T215 VanDerWaalsContact O-N 3.07Å; R211-T215 PolarHBondContact O-OG1 2.9Å; V212-T215 WeakPolarHBondContact O-CB 3.23Å; V212-T215 PolarHBondContact O-N 2.99Å; I213-T215 VanDerWaalsContact C-N 3.25Å; I213-T215 PolarHBondContact O-N 2.85Å; T215-G218 PolarHBondContact O-N 3.36Å; T215-M219 HydrophobicContact CG2-CE 4.15Å; T215-M219 WeakPolarHBondContact O-CG 3.43Å; T215-M219 PolarHBondContact O-N 3.48Å
216	M	96.1	Very high	93.1	Very high	96 Å²	96	43.4 Å²	43.4	47%	0.473	23%	0.228	S	C	.	.	H	α-helix	trans	-63	-43.4	176.6	-64.7	-60.7	143.5	0	0	111.9	V212 I213 G218 M219 V220	V212-M216 HydrophobicContact CG1-CE 4.29Å; V212-M216 HydrophobicContact CG1-CG 4.45Å; V212-M216 WeakPolarHBondContact O-CG 3.4Å; V212-M216 PolarHBondContact O-N 3.2Å; I213-M216 PolarHBondContact O-N 3.45Å; M216-G218 VanDerWaalsContact C-N 3.33Å; M216-G218 PolarHBondContact O-N 3.34Å; M216-M219 HydrophobicContact CE-CE 3.46Å; M216-M219 VanDerWaalsContact CE-CE 3.46Å; M216-M219 HydrophobicContact CG-CE 4.42Å; M216-M219 PolarHBondContact O-N 3.19Å; M216-M219 HydrophobicContact SD-CE 3.28Å; M216-M219 WeakPolarHBondContact SD-CE 3.3Å; M216-V220 WeakPolarHBondContact O-CB 3.4Å; M216-V220 VanDerWaalsContact O-CG2 3.3Å; M216-V220 WeakPolarHBondContact O-CG2 3.19Å; M216-V220 PolarHBondContact O-N 2.94Å
217	F	95.4	Very high	92.4	Very high	14 Å²	14	50.5 Å²	50.5	6%	0.061	26%	0.26	C	S	.	.	H	α-helix	trans	-58.1	-45.6	176.4	175.4	-91.9	0	0	0	111.1	V163 P164 I213 V214 V220 L221 Y375 L454	V163-F217 HydrophobicContact CB-CD2 4.02Å; V163-F217 HydrophobicContact CB-CE2 3.74Å; V163-F217 HydrophobicContact CG1-CD2 3.59Å; V163-F217 HydrophobicContact CG1-CE2 3.68Å; V163-F217 HydrophobicContact CG2-CE2 3.95Å; P164-F217 HydrophobicContact CG-CB 4.31Å; I213-F217 VanDerWaalsContact O-CB 3.28Å; I213-F217 WeakPolarHBondContact O-CB 3.43Å; I213-F217 PolarHBondContact O-N 3.23Å; V214-F217 PolarHBondContact O-N 3.42Å; F217-V220 PolarHBondContact O-N 3.4Å; F217-L221 HydrophobicContact CD2-CD1 3.67Å; F217-L221 HydrophobicContact CD2-CG 4.4Å; F217-L221 HydrophobicContact CE1-CD1 4.29Å; F217-L221 HydrophobicContact CE2-CD1 3.17Å; F217-L221 HydrophobicContact CE2-CG 4.31Å; F217-L221 HydrophobicContact CG-CD1 4.42Å; F217-L221 HydrophobicContact CZ-CD1 3.54Å; F217-L221 WeakPolarHBondContact O-CB 3.14Å; F217-L221 PolarHBondContact O-N 3.23Å; F217-Y375 HydrophobicContact CE1-CD1 4.18Å; F217-Y375 AromaticContact CE1-CD2 3.7Å; F217-Y375 HydrophobicContact CE1-CD2 3.7Å; F217-Y375 HydrophobicContact CE1-CE1 4.07Å; F217-Y375 AromaticContact CE1-CE2 3.55Å; F217-Y375 HydrophobicContact CE1-CE2 3.55Å; F217-Y375 HydrophobicContact CE1-CG 4.01Å; F217-Y375 AromaticContact CE1-CZ 3.75Å; F217-Y375 HydrophobicContact CZ-CD1 4.2Å; F217-Y375 AromaticContact CZ-CD2 3.6Å; F217-Y375 HydrophobicContact CZ-CD2 3.6Å; F217-Y375 AromaticContact CZ-CE2 3.97Å; F217-Y375 HydrophobicContact CZ-CE2 3.97Å; F217-Y375 AromaticContact CZ-CG 3.72Å; F217-Y375 HydrophobicContact CZ-CG 3.72Å; F217-L454 HydrophobicContact CD1-CD2 3.75Å; F217-L454 HydrophobicContact CE1-CD2 4.04Å
218	G	93.8	Very high	91.4	Very high	12 Å²	12	49.8 Å²	49.8	12%	0.124	26%	0.262	C	S	.	.	H	α-helix	trans	-62.6	-41.7	174.4	0	0	0	0	0	113.9	V214 T215 M216 G222	V214-G218 PolarHBondContact O-N 2.98Å; T215-G218 PolarHBondContact O-N 3.36Å; M216-G218 VanDerWaalsContact C-N 3.33Å; M216-G218 PolarHBondContact O-N 3.34Å; G218-G222 WeakPolarHBondContact O-CA 3.21Å; G218-G222 PolarHBondContact O-N 2.91Å
219	M	94.1	Very high	89.9	Confident	110 Å²	110	51 Å²	51	54%	0.542	27%	0.267	S	S	.	.	H	α-helix	trans	-68.8	-34.5	177.8	-71.2	-171.2	-61.8	0	0	113	T215 M216 P223	T215-M219 HydrophobicContact CG2-CE 4.15Å; T215-M219 WeakPolarHBondContact O-CG 3.43Å; T215-M219 PolarHBondContact O-N 3.48Å; M216-M219 HydrophobicContact CE-CE 3.46Å; M216-M219 VanDerWaalsContact CE-CE 3.46Å; M216-M219 HydrophobicContact CG-CE 4.42Å; M216-M219 PolarHBondContact O-N 3.19Å; M216-M219 HydrophobicContact SD-CE 3.28Å; M216-M219 WeakPolarHBondContact SD-CE 3.3Å; M219-P223 WeakPolarHBondContact O-CD 3.3Å; M219-P223 VanDerWaalsContact O-CG 3.26Å; M219-P223 WeakPolarHBondContact O-CG 2.76Å
220	V	92.6	Very high	88.3	Confident	94 Å²	94	54.5 Å²	54.5	57%	0.57	29%	0.288	S	S	*	.	H	α-helix	trans	-80.1	-50.2	-179.3	173.3	0	0	0	0	111.2	M216 F217 F224	M216-V220 WeakPolarHBondContact O-CB 3.4Å; M216-V220 VanDerWaalsContact O-CG2 3.3Å; M216-V220 WeakPolarHBondContact O-CG2 3.19Å; M216-V220 PolarHBondContact O-N 2.94Å; F217-V220 PolarHBondContact O-N 3.4Å; V220-F224 VanDerWaalsContact O-CD2 3.27Å; V220-F224 WeakPolarHBondContact O-CD2 3.47Å; V220-F224 WeakPolarHBondContact O-CE2 3.46Å
221	L	91.5	Very high	86.5	Confident	22 Å²	22	63.5 Å²	63.5	12%	0.115	33%	0.33	C	S	.	.	H	α-helix	trans	-92.9	-26.2	-173.4	-59.7	-174.8	0	0	0	113.9	F217 F224 Y375	F217-L221 HydrophobicContact CD2-CD1 3.67Å; F217-L221 HydrophobicContact CD2-CG 4.4Å; F217-L221 HydrophobicContact CE1-CD1 4.29Å; F217-L221 HydrophobicContact CE2-CD1 3.17Å; F217-L221 HydrophobicContact CE2-CG 4.31Å; F217-L221 HydrophobicContact CG-CD1 4.42Å; F217-L221 HydrophobicContact CZ-CD1 3.54Å; F217-L221 WeakPolarHBondContact O-CB 3.14Å; F217-L221 PolarHBondContact O-N 3.23Å; L221-F224 WeakPolarHBondContact O-CB 3.45Å; L221-F224 PolarHBondContact O-N 3.08Å; L221-F224 VanDerWaalsContact O-N 3.15Å; L221-Y375 HydrophobicContact CB-CD1 3.94Å; L221-Y375 HydrophobicContact CB-CE1 4.4Å; L221-Y375 HydrophobicContact CD1-CD1 4.31Å; L221-Y375 HydrophobicContact CD1-CG 4.43Å
222	G	89.4	Confident	85	Confident	2 Å²	2	61.7 Å²	61.7	2%	0.021	33%	0.326	C	S	.	.	H	α-helix	trans	-53.3	-46.9	178.1	0	0	0	0	0	113.7	G218 F224 V225 F226	G218-G222 WeakPolarHBondContact O-CA 3.21Å; G218-G222 PolarHBondContact O-N 2.91Å; G222-F224 PolarHBondContact O-N 3.46Å; G222-F224 VanDerWaalsContact O-N 3.16Å; G222-V225 WeakPolarHBondContact O-CB 3.38Å; G222-V225 PolarHBondContact O-N 3.25Å; G222-F226 WeakPolarHBondContact O-CD2 3.39Å
223	P	89.9	Confident	83.7	Confident	52 Å²	52	65.6 Å²	65.6	34%	0.338	33%	0.332	S	S	.	.	H	α-helix	trans	-55.4	-33.4	177.9	-28.8	36.6	0	0	0	114.3	M219 V225 F226 F227	M219-P223 WeakPolarHBondContact O-CD 3.3Å; M219-P223 VanDerWaalsContact O-CG 3.26Å; M219-P223 WeakPolarHBondContact O-CG 2.76Å; P223-V225 PolarHBondContact O-N 3.01Å; P223-F226 WeakPolarHBondContact O-CB 3.5Å; P223-F226 PolarHBondContact O-N 3.4Å; P223-F227 HydrophobicContact CB-CE2 4.15Å; P223-F227 WeakPolarHBondContact O-CD2 3.23Å; P223-F227 PolarHBondContact O-N 2.89Å
224	F	87.8	Confident	82.6	Confident	84 Å²	84	73.1 Å²	73.1	37%	0.368	36%	0.361	S	S	.	.	H	α-helix	trans	-62.9	-28.2	179.2	-69.2	-98.9	0	0	0	112.7	V220 L221 G222 F226 G228 M229 P376	V220-F224 VanDerWaalsContact O-CD2 3.27Å; V220-F224 WeakPolarHBondContact O-CD2 3.47Å; V220-F224 WeakPolarHBondContact O-CE2 3.46Å; L221-F224 WeakPolarHBondContact O-CB 3.45Å; L221-F224 PolarHBondContact O-N 3.08Å; L221-F224 VanDerWaalsContact O-N 3.15Å; G222-F224 PolarHBondContact O-N 3.46Å; G222-F224 VanDerWaalsContact O-N 3.16Å; F224-F226 VanDerWaalsContact C-N 3.31Å; F224-G228 PolarHBondContact O-N 2.87Å; F224-M229 HydrophobicContact CD1-CE 3.1Å; F224-M229 HydrophobicContact CE1-CE 3.23Å; F224-M229 HydrophobicContact CG-CE 4.13Å; F224-M229 HydrophobicContact CZ-CE 4.36Å; F224-P376 HydrophobicContact CB-CB 3.67Å; F224-P376 HydrophobicContact CB-CG 3.74Å; F224-P376 HydrophobicContact CG-CG 4.33Å
225	V	86.5	Confident	81.5	Confident	0 Å²	0	80 Å²	80	0%	0	39%	0.388	C	S	.	.	H	α-helix	trans	-67.3	-33.4	174.9	-177.8	0	0	0	0	111.2	G222 P223 R383 P446 V449 V450	G222-V225 WeakPolarHBondContact O-CB 3.38Å; G222-V225 PolarHBondContact O-N 3.25Å; P223-V225 PolarHBondContact O-N 3.01Å; V225-R383 VanDerWaalsContact O-CZ 3.27Å; V225-R383 PolarHBondContact O-NH1 2.92Å; V225-R383 PolarHBondContact O-NH2 3.37Å; V225-P446 HydrophobicContact CG1-CB 4.4Å; V225-V449 HydrophobicContact CG1-CG1 4.03Å; V225-V450 HydrophobicContact CB-CG2 3.92Å; V225-V450 HydrophobicContact CG1-CG2 4.22Å; V225-V450 HydrophobicContact CG2-CG2 3.81Å
226	F	86.1	Confident	80.3	Confident	67 Å²	67	81.4 Å²	81.4	29%	0.294	39%	0.389	S	S	.	.	H	α-helix	trans	-67.2	-51.1	177.6	-68.5	-102.8	0	0	0	110.8	G222 P223 F224 G228 R383 P446 L447	G222-F226 WeakPolarHBondContact O-CD2 3.39Å; P223-F226 WeakPolarHBondContact O-CB 3.5Å; P223-F226 PolarHBondContact O-N 3.4Å; F224-F226 VanDerWaalsContact C-N 3.31Å; F226-G228 VanDerWaalsContact C-N 3.26Å; F226-G228 PolarHBondContact O-N 3.21Å; F226-R383 PolarHBondContact O-NH1 2.78Å; F226-P446 HydrophobicContact CD1-CB 3.72Å; F226-P446 HydrophobicContact CD1-CG 4.07Å; F226-P446 HydrophobicContact CD2-CB 4.18Å; F226-P446 HydrophobicContact CE1-CB 3.74Å; F226-P446 HydrophobicContact CE1-CG 4.29Å; F226-P446 HydrophobicContact CE2-CB 4.19Å; F226-P446 HydrophobicContact CG-CB 3.95Å; F226-P446 HydrophobicContact CZ-CB 3.98Å; F226-L447 HydrophobicContact CZ-CB 4.17Å; F226-L447 HydrophobicContact CZ-CD1 4.45Å
227	F	77	Confident	79.5	Confident	157 Å²	157	81.7 Å²	81.7	69%	0.689	39%	0.386	S	S	*	.	H	α-helix	trans	-74.7	-8.4	-172.3	-61	-65	0	0	0	114.8	P223 M229	P223-F227 HydrophobicContact CB-CE2 4.15Å; P223-F227 WeakPolarHBondContact O-CD2 3.23Å; P223-F227 PolarHBondContact O-N 2.89Å; F227-M229 HydrophobicContact CB-CG 3.99Å; F227-M229 PolarHBondContact O-N 3.42Å
228	G	70.9	Confident	79	Confident	20 Å²	20	83.6 Å²	83.6	21%	0.206	40%	0.399	C	S	.	.	T	Hydrogen-bonded Turn	trans	62.7	28.3	176	0	0	0	0	0	113.5	F224 F226 T230	F224-G228 PolarHBondContact O-N 2.87Å; F226-G228 VanDerWaalsContact C-N 3.26Å; F226-G228 PolarHBondContact O-N 3.21Å; G228-T230 PolarHBondContact O-N 2.9Å; G228-T230 VanDerWaalsContact O-N 3.11Å
229	M	62.6	Low	78.5	Confident	96 Å²	96	83.2 Å²	83.2	47%	0.473	39%	0.394	S	S	.	.			trans	-69.7	108.4	-178.4	-65.6	-162.1	-64.6	0	0	109.9	F224 F227	F224-M229 HydrophobicContact CD1-CE 3.1Å; F224-M229 HydrophobicContact CE1-CE 3.23Å; F224-M229 HydrophobicContact CG-CE 4.13Å; F224-M229 HydrophobicContact CZ-CE 4.36Å; F227-M229 HydrophobicContact CB-CG 3.99Å; F227-M229 PolarHBondContact O-N 3.42Å
230	T	62.3	Low	78	Confident	88 Å²	88	79 Å²	79	54%	0.54	38%	0.376	S	S	.	.			trans	-103	-6.7	-176.5	51.3	0	0	0	0	114	G228 T232	G228-T230 PolarHBondContact O-N 2.9Å; G228-T230 VanDerWaalsContact O-N 3.11Å; T230-T232 VanDerWaalsContact C-N 3.31Å; T230-T232 PolarHBondContact O-N 3.33Å
231	Q	58	Low	77.8	Confident	190 Å²	190	81.1 Å²	81.1	89%	0.888	38%	0.377	S	S	*	.			trans	-80.3	76.9	-176	-67.2	-123.4	10.9	0	0	111.4
232	T	64.9	Low	77.8	Confident	26 Å²	26	81.7 Å²	81.7	16%	0.16	38%	0.38	C	S	.	.			trans	-119.5	11.9	-178.9	58.6	0	0	0	0	113.8	T230 Y234 Y235 Q236 I377	T230-T232 VanDerWaalsContact C-N 3.31Å; T230-T232 PolarHBondContact O-N 3.33Å; T232-Y234 PolarHBondContact O-N 3.27Å; T232-Y234 VanDerWaalsContact O-N 3.12Å; T232-Y235 CarbonylContact O-C 3.56Å; T232-Y235 WeakPolarHBondContact O-CA 3.34Å; T232-Y235 WeakPolarHBondContact O-CB 3.24Å; T232-Y235 PolarHBondContact O-N 2.99Å; T232-Q236 PolarHBondContact O-N 3.45Å; T232-I377 HydrophobicContact CG2-CD1 4.24Å; T232-I377 HydrophobicContact CG2-CG1 4.44Å; T232-I377 VanDerWaalsContact OG1-CD1 3.23Å; T232-I377 WeakPolarHBondContact OG1-CD1 3.43Å
233	R	69.1	Low	77.9	Confident	165 Å²	165	82.6 Å²	82.6	62%	0.623	38%	0.383	S	S	*	.	H	α-helix	trans	-51.9	-42.4	-176	-172.6	-179.4	176.9	-171.5	-3.8	112.6	Q236 Y237	R233-Q236 PolarHBondContact O-N 3.35Å; R233-Y237 HydrophobicContact CG-CD2 4.2Å; R233-Y237 HydrophobicContact CG-CE2 3.6Å; R233-Y237 PolarHBondContact NE-OH 2.91Å; R233-Y237 VanDerWaalsContact NE-OH 3.1Å; R233-Y237 PolarHBondContact NH2-OH 3.38Å; R233-Y237 WeakPolarHBondContact O-CD2 3.36Å; R233-Y237 PolarHBondContact O-N 3.44Å
234	Y	74.1	Confident	77.9	Confident	173 Å²	173	85 Å²	85	68%	0.678	39%	0.385	S	S	*	.	H	α-helix	trans	-64.9	-46.5	176.4	-176.8	-100.1	0	0	0	112.2	T232 Q236 Y237 V238	T232-Y234 PolarHBondContact O-N 3.27Å; T232-Y234 VanDerWaalsContact O-N 3.12Å; Y234-Q236 VanDerWaalsContact C-N 3.28Å; Y234-Q236 PolarHBondContact O-N 3.4Å; Y234-Y237 PolarHBondContact O-N 2.89Å; Y234-Y237 VanDerWaalsContact O-N 3.17Å; Y234-V238 HydrophobicContact CD1-CG2 4.17Å; Y234-V238 HydrophobicContact CE1-CG2 3.74Å; Y234-V238 HydrophobicContact CE2-CG2 4.49Å; Y234-V238 WeakPolarHBondContact O-CG2 3.35Å; Y234-V238 PolarHBondContact O-N 3.17Å
235	Y	73.7	Confident	78.2	Confident	148 Å²	148	84.1 Å²	84.1	58%	0.58	38%	0.384	S	S	*	.	H	α-helix	trans	-60.5	-36.3	176.4	-68.8	-71.8	0	0	0	112.5	T232 V238 A239	T232-Y235 CarbonylContact O-C 3.56Å; T232-Y235 WeakPolarHBondContact O-CA 3.34Å; T232-Y235 WeakPolarHBondContact O-CB 3.24Å; T232-Y235 PolarHBondContact O-N 2.99Å; Y235-V238 PolarHBondContact O-N 3.16Å; Y235-A239 WeakPolarHBondContact O-CB 3.32Å; Y235-A239 PolarHBondContact O-N 3.5Å
236	Q	71	Confident	78.6	Confident	93 Å²	93	84.1 Å²	84.1	44%	0.435	38%	0.384	S	S	.	.	H	α-helix	trans	-65.8	-39.3	175.9	-71.7	-177.3	-15.7	0	0	112.4	T232 R233 Y234 S240	T232-Q236 PolarHBondContact O-N 3.45Å; R233-Q236 PolarHBondContact O-N 3.35Å; Y234-Q236 VanDerWaalsContact C-N 3.28Å; Y234-Q236 PolarHBondContact O-N 3.4Å; Q236-S240 VanDerWaalsContact O-CB 3.31Å; Q236-S240 WeakPolarHBondContact O-CB 3.49Å; Q236-S240 PolarHBondContact O-N 2.88Å
237	Y	79	Confident	78.9	Confident	103 Å²	103	80.9 Å²	80.9	40%	0.404	37%	0.37	S	S	.	.	H	α-helix	trans	-65.2	-45.8	174.4	-71.3	-54.9	0	0	0	111.7	Y15 R233 Y234 S240 F241	Y15-Y237 PolarHBondContact OH-OH 2.95Å; R233-Y237 HydrophobicContact CG-CD2 4.2Å; R233-Y237 HydrophobicContact CG-CE2 3.6Å; R233-Y237 PolarHBondContact NE-OH 2.91Å; R233-Y237 VanDerWaalsContact NE-OH 3.1Å; R233-Y237 PolarHBondContact NH2-OH 3.38Å; R233-Y237 WeakPolarHBondContact O-CD2 3.36Å; R233-Y237 PolarHBondContact O-N 3.44Å; Y234-Y237 PolarHBondContact O-N 2.89Å; Y234-Y237 VanDerWaalsContact O-N 3.17Å; Y237-S240 PolarHBondContact O-N 3.12Å; Y237-F241 PolarHBondContact O-N 2.59Å
238	V	84.2	Confident	79.8	Confident	54 Å²	54	77.3 Å²	77.3	33%	0.327	36%	0.361	S	S	.	.	H	α-helix	trans	-61.4	-46.2	176.1	175.5	0	0	0	0	110.6	Y234 Y235 S240 F241 L242	Y234-V238 HydrophobicContact CD1-CG2 4.17Å; Y234-V238 HydrophobicContact CE1-CG2 3.74Å; Y234-V238 HydrophobicContact CE2-CG2 4.49Å; Y234-V238 WeakPolarHBondContact O-CG2 3.35Å; Y234-V238 PolarHBondContact O-N 3.17Å; Y235-V238 PolarHBondContact O-N 3.16Å; V238-S240 VanDerWaalsContact C-N 3.35Å; V238-S240 PolarHBondContact O-N 3.06Å; V238-F241 PolarHBondContact O-N 3.37Å; V238-L242 HydrophobicContact CG1-CD1 3.93Å; V238-L242 HydrophobicContact CG1-CG 4.25Å; V238-L242 VanDerWaalsContact O-CG 3.31Å; V238-L242 WeakPolarHBondContact O-CG 3.43Å; V238-L242 PolarHBondContact O-N 3.12Å
239	A	83.2	Confident	80.9	Confident	4 Å²	4	78.2 Å²	78.2	3%	0.033	36%	0.361	C	S	.	.	H	α-helix	trans	-62.5	-40.4	178.8	0	0	0	0	0	112.2	Y235 R243 T370	Y235-A239 WeakPolarHBondContact O-CB 3.32Å; Y235-A239 PolarHBondContact O-N 3.5Å; A239-R243 WeakPolarHBondContact O-CB 3.19Å; A239-R243 PolarHBondContact O-N 3.12Å; A239-T370 HydrophobicContact CB-CG2 3.91Å
240	S	84.3	Confident	82.4	Confident	21 Å²	21	73.6 Å²	73.6	15%	0.147	34%	0.338	C	S	.	.	H	α-helix	trans	-63.5	-43.9	174.5	179.6	0	0	0	0	111.5	N18 Q236 Y237 V238 R243 W244	N18-S240 PolarHBondContact ND2-OG 3.28Å; N18-S240 PolarHBondContact OD1-OG 3.22Å; Q236-S240 VanDerWaalsContact O-CB 3.31Å; Q236-S240 WeakPolarHBondContact O-CB 3.49Å; Q236-S240 PolarHBondContact O-N 2.88Å; Y237-S240 PolarHBondContact O-N 3.12Å; V238-S240 VanDerWaalsContact C-N 3.35Å; V238-S240 PolarHBondContact O-N 3.06Å; S240-R243 WeakPolarHBondContact O-CB 3.41Å; S240-R243 PolarHBondContact O-N 2.92Å; S240-W244 PolarHBondContact O-N 3.15Å; S240-W244 VanDerWaalsContact O-N 3.08Å
241	F	88.9	Confident	83.9	Confident	138 Å²	138	70.9 Å²	70.9	61%	0.605	32%	0.321	S	S	*	.	H	α-helix	trans	-61.3	-50.6	176	173.6	-99	0	0	0	112.1	Y237 V238 R243 W244 L245	Y237-F241 PolarHBondContact O-N 2.59Å; V238-F241 PolarHBondContact O-N 3.37Å; F241-R243 PolarHBondContact O-N 2.94Å; F241-W244 PolarHBondContact O-N 3.02Å; F241-L245 HydrophobicContact CE1-CD2 4.15Å; F241-L245 HydrophobicContact CZ-CD2 4.35Å; F241-L245 WeakPolarHBondContact O-CB 3.37Å; F241-L245 PolarHBondContact O-N 2.78Å
242	L	90.8	Very high	85.7	Confident	34 Å²	34	65.7 Å²	65.7	18%	0.178	30%	0.302	C	S	.	.	H	α-helix	trans	-58.5	-38.7	177.5	-68.8	176.7	0	0	0	111.6	V238 L245 S246 F362 Y366 F369 T370	V238-L242 HydrophobicContact CG1-CD1 3.93Å; V238-L242 HydrophobicContact CG1-CG 4.25Å; V238-L242 VanDerWaalsContact O-CG 3.31Å; V238-L242 WeakPolarHBondContact O-CG 3.43Å; V238-L242 PolarHBondContact O-N 3.12Å; L242-L245 PolarHBondContact O-N 3.35Å; L242-S246 WeakPolarHBondContact O-CB 3.12Å; L242-S246 PolarHBondContact O-N 3.16Å; L242-S246 PolarHBondContact O-OG 3.41Å; L242-F362 HydrophobicContact CD2-CE2 3.76Å; L242-F362 HydrophobicContact CD2-CZ 4.13Å; L242-Y366 HydrophobicContact CB-CD2 4.42Å; L242-F369 HydrophobicContact CD1-CB 4.29Å; L242-T370 HydrophobicContact CB-CG2 3.99Å; L242-T370 HydrophobicContact CD1-CG2 4.42Å
243	R	91	Very high	87	Confident	22 Å²	22	68 Å²	68	8%	0.083	31%	0.309	C	S	.	.	H	α-helix	trans	-60	-55	176.5	177	179.5	-46.6	152.4	6	112.8	N18 V21 A239 S240 F241 L245 S246 F247 Y366	N18-R243 PolarHBondContact O-NH1 3.35Å; V21-R243 WeakPolarHBondContact O-CD 3.47Å; V21-R243 PolarHBondContact O-NE 3.42Å; V21-R243 PolarHBondContact O-NH1 3.19Å; A239-R243 WeakPolarHBondContact O-CB 3.19Å; A239-R243 PolarHBondContact O-N 3.12Å; S240-R243 WeakPolarHBondContact O-CB 3.41Å; S240-R243 PolarHBondContact O-N 2.92Å; F241-R243 PolarHBondContact O-N 2.94Å; R243-L245 VanDerWaalsContact C-N 3.29Å; R243-L245 PolarHBondContact O-N 3.24Å; R243-S246 PolarHBondContact O-N 2.9Å; R243-F247 HydrophobicContact CG-CD2 3.48Å; R243-F247 VanDerWaalsContact CG-CD2 3.48Å; R243-F247 HydrophobicContact CG-CE2 3.35Å; R243-F247 VanDerWaalsContact O-CD2 3.25Å; R243-F247 WeakPolarHBondContact O-CD2 3.2Å; R243-F247 PolarHBondContact O-N 2.78Å; R243-Y366 HydrophobicContact CB-CE2 3.73Å; R243-Y366 HydrophobicContact CG-CE2 4.26Å; R243-Y366 VanDerWaalsContact CG-OH 3.31Å; R243-Y366 WeakPolarHBondContact CG-OH 3.16Å
244	W	91.3	Very high	88	Confident	101 Å²	101	60.2 Å²	60.2	38%	0.383	28%	0.279	S	S	.	.	H	α-helix	trans	-62.9	-40.1	-179.9	-75.1	109.3	0	0	0	111.2	N18 V21 S240 F241 F247 T248 F319	N18-W244 PolarHBondContact OD1-NE1 2.88Å; V21-W244 HydrophobicContact CB-CZ2 4.48Å; V21-W244 HydrophobicContact CG2-CH2 4.06Å; V21-W244 HydrophobicContact CG2-CZ2 4.27Å; S240-W244 PolarHBondContact O-N 3.15Å; S240-W244 VanDerWaalsContact O-N 3.08Å; F241-W244 PolarHBondContact O-N 3.02Å; W244-F247 PolarHBondContact O-N 3.47Å; W244-T248 WeakPolarHBondContact O-CB 3.48Å; W244-T248 PolarHBondContact O-N 3.25Å; W244-T248 PolarHBondContact O-OG1 3.45Å; W244-F319 HydrophobicContact CZ3-CD2 4.5Å
245	L	93.7	Very high	88.9	Confident	66 Å²	66	54.8 Å²	54.8	35%	0.346	26%	0.264	S	S	.	.	H	α-helix	trans	-59	-50.3	174.8	-178	58.1	0	0	0	112	F241 L242 R243 T248 I249 F362	F241-L245 HydrophobicContact CE1-CD2 4.15Å; F241-L245 HydrophobicContact CZ-CD2 4.35Å; F241-L245 WeakPolarHBondContact O-CB 3.37Å; F241-L245 PolarHBondContact O-N 2.78Å; L242-L245 PolarHBondContact O-N 3.35Å; R243-L245 VanDerWaalsContact C-N 3.29Å; R243-L245 PolarHBondContact O-N 3.24Å; L245-T248 PolarHBondContact O-N 2.57Å; L245-I249 HydrophobicContact CD1-CD1 4.02Å; L245-I249 HydrophobicContact CD1-CG1 4.42Å; L245-I249 HydrophobicContact CG-CD1 4.06Å; L245-I249 VanDerWaalsContact O-CG1 3.29Å; L245-I249 WeakPolarHBondContact O-CG1 3.35Å; L245-I249 PolarHBondContact O-N 3.14Å; L245-F362 HydrophobicContact CB-CZ 4.28Å; L245-F362 HydrophobicContact CD2-CE1 4.2Å; L245-F362 HydrophobicContact CD2-CE2 4.21Å; L245-F362 HydrophobicContact CD2-CZ 3.61Å; L245-F362 HydrophobicContact CG-CE1 4.03Å; L245-F362 HydrophobicContact CG-CZ 3.84Å
246	S	93.9	Very high	89.7	Confident	0 Å²	0	50.8 Å²	50.8	0%	0	26%	0.257	C	S	.	.	H	α-helix	trans	-60.4	-47.2	177.8	-64.8	0	0	0	0	112.4	L242 R243 T248 I249 M250 F362 Y366	L242-S246 WeakPolarHBondContact O-CB 3.12Å; L242-S246 PolarHBondContact O-N 3.16Å; L242-S246 PolarHBondContact O-OG 3.41Å; R243-S246 PolarHBondContact O-N 2.9Å; S246-T248 PolarHBondContact O-N 2.79Å; S246-I249 PolarHBondContact O-N 2.95Å; S246-M250 WeakPolarHBondContact O-CG 3.44Å; S246-M250 PolarHBondContact O-N 3.2Å; S246-F362 VanDerWaalsContact OG-CE1 3.22Å; S246-F362 WeakPolarHBondContact OG-CE1 3.22Å; S246-Y366 VanDerWaalsContact OG-CB 3.3Å; S246-Y366 WeakPolarHBondContact OG-CB 3.33Å; S246-Y366 WeakPolarHBondContact OG-CD2 3.35Å; S246-Y366 VanDerWaalsContact OG-CG 3.23Å
247	F	93.8	Very high	90.5	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-63.9	-40.3	179.3	-77.1	-53.1	0	0	0	112.8	V21 A25 L26 R243 W244 M250 V251 F319 I323	V21-F247 HydrophobicContact CG1-CD2 3.93Å; V21-F247 HydrophobicContact CG1-CE2 3.61Å; V21-F247 HydrophobicContact CG1-CZ 4.48Å; A25-F247 HydrophobicContact CB-CE1 3.95Å; A25-F247 HydrophobicContact CB-CZ 3.68Å; L26-F247 HydrophobicContact CD2-CE1 3.75Å; L26-F247 HydrophobicContact CD2-CZ 4.08Å; L26-F247 HydrophobicContact CG-CE1 4.46Å; L26-F247 HydrophobicContact CG-CZ 4.4Å; R243-F247 HydrophobicContact CG-CD2 3.48Å; R243-F247 VanDerWaalsContact CG-CD2 3.48Å; R243-F247 HydrophobicContact CG-CE2 3.35Å; R243-F247 VanDerWaalsContact O-CD2 3.25Å; R243-F247 WeakPolarHBondContact O-CD2 3.2Å; R243-F247 PolarHBondContact O-N 2.78Å; W244-F247 PolarHBondContact O-N 3.47Å; F247-M250 HydrophobicContact CD1-CE 3.27Å; F247-M250 HydrophobicContact CE1-CE 3.68Å; F247-M250 HydrophobicContact CG-CE 4.08Å; F247-M250 PolarHBondContact O-N 2.89Å; F247-V251 WeakPolarHBondContact O-CG2 3.34Å; F247-V251 PolarHBondContact O-N 3.47Å; F247-F319 HydrophobicContact CB-CE2 3.84Å; F247-F319 HydrophobicContact CB-CZ 3.69Å; F247-F319 AromaticContact CD1-CZ 3.7Å; F247-F319 HydrophobicContact CD1-CZ 3.7Å; F247-F319 HydrophobicContact CD2-CE1 4.46Å; F247-F319 AromaticContact CD2-CZ 3.82Å; F247-F319 HydrophobicContact CD2-CZ 3.82Å; F247-F319 HydrophobicContact CE1-CZ 4.28Å; F247-F319 HydrophobicContact CE2-CZ 4.36Å; F247-F319 HydrophobicContact CG-CE1 4.47Å; F247-F319 HydrophobicContact CG-CE2 4.18Å; F247-F319 AromaticContact CG-CZ 3.49Å; F247-F319 HydrophobicContact CG-CZ 3.49Å; F247-F319 VanDerWaalsContact CG-CZ 3.49Å; F247-I323 HydrophobicContact CD1-CD1 3.48Å; F247-I323 VanDerWaalsContact CD1-CD1 3.48Å; F247-I323 HydrophobicContact CE1-CD1 3.61Å
248	T	94.3	Very high	90.9	Very high	82 Å²	82	42.6 Å²	42.6	50%	0.503	22%	0.222	S	C	.	.	H	α-helix	trans	-61.4	-46.7	174.4	-61.5	0	0	0	0	111.3	W244 L245 S246 M250 V251 V252	W244-T248 WeakPolarHBondContact O-CB 3.48Å; W244-T248 PolarHBondContact O-N 3.25Å; W244-T248 PolarHBondContact O-OG1 3.45Å; L245-T248 PolarHBondContact O-N 2.57Å; S246-T248 PolarHBondContact O-N 2.79Å; T248-M250 PolarHBondContact O-N 3.42Å; T248-V251 PolarHBondContact O-N 3.07Å; T248-V252 HydrophobicContact CG2-CG2 4.32Å; T248-V252 WeakPolarHBondContact O-CB 3.36Å; T248-V252 VanDerWaalsContact O-CG2 3.24Å; T248-V252 WeakPolarHBondContact O-CG2 3.38Å; T248-V252 PolarHBondContact O-N 3Å
249	I	94.7	Very high	91.1	Very high	38 Å²	38	45.5 Å²	45.5	20%	0.195	24%	0.24	C	C	.	.	H	α-helix	trans	-60	-46.2	177.4	-67.3	167.3	0	0	0	110.7	L245 S246 V252 W253 I359 F362 L363	L245-I249 HydrophobicContact CD1-CD1 4.02Å; L245-I249 HydrophobicContact CD1-CG1 4.42Å; L245-I249 HydrophobicContact CG-CD1 4.06Å; L245-I249 VanDerWaalsContact O-CG1 3.29Å; L245-I249 WeakPolarHBondContact O-CG1 3.35Å; L245-I249 PolarHBondContact O-N 3.14Å; S246-I249 PolarHBondContact O-N 2.95Å; I249-V252 PolarHBondContact O-N 3.5Å; I249-W253 VanDerWaalsContact O-CB 3.26Å; I249-W253 WeakPolarHBondContact O-CB 3.16Å; I249-W253 PolarHBondContact O-N 2.89Å; I249-I359 HydrophobicContact CG2-CG2 3.75Å; I249-F362 HydrophobicContact CD1-CD1 4.11Å; I249-F362 HydrophobicContact CD1-CE1 3.93Å; I249-L363 HydrophobicContact CB-CD2 4.23Å; I249-L363 HydrophobicContact CG2-CD1 3.96Å; I249-L363 HydrophobicContact CG2-CD2 4.13Å; I249-L363 HydrophobicContact CG2-CG 4.35Å
250	M	94	Very high	91.2	Very high	0 Å²	0	52 Å²	52	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-62.1	-47.8	-179.8	-73.2	-172.1	-73.2	0	0	112.4	L26 S246 F247 T248 W253 A254 Y338 V339 F342 L363	L26-M250 HydrophobicContact CD2-CE 4.22Å; S246-M250 WeakPolarHBondContact O-CG 3.44Å; S246-M250 PolarHBondContact O-N 3.2Å; F247-M250 HydrophobicContact CD1-CE 3.27Å; F247-M250 HydrophobicContact CE1-CE 3.68Å; F247-M250 HydrophobicContact CG-CE 4.08Å; F247-M250 PolarHBondContact O-N 2.89Å; T248-M250 PolarHBondContact O-N 3.42Å; M250-W253 PolarHBondContact O-N 2.87Å; M250-A254 WeakPolarHBondContact O-CB 3.37Å; M250-A254 PolarHBondContact O-N 2.96Å; M250-Y338 HydrophobicContact CB-CE1 4.08Å; M250-Y338 HydrophobicContact SD-CD1 3.8Å; M250-Y338 HydrophobicContact SD-CE1 4.24Å; M250-V339 HydrophobicContact CE-CG1 4.01Å; M250-V339 HydrophobicContact SD-CB 4.35Å; M250-V339 HydrophobicContact SD-CG1 3.5Å; M250-V339 VanDerWaalsContact SD-CG1 3.5Å; M250-F342 HydrophobicContact CB-CD2 4.47Å; M250-F342 HydrophobicContact CB-CE1 4.4Å; M250-F342 HydrophobicContact CB-CE2 3.67Å; M250-F342 HydrophobicContact CB-CZ 3.62Å; M250-F342 HydrophobicContact CG-CD2 3.79Å; M250-F342 HydrophobicContact CG-CE2 3.43Å; M250-F342 VanDerWaalsContact CG-CE2 3.43Å; M250-F342 HydrophobicContact CG-CG 4.48Å; M250-F342 HydrophobicContact CG-CZ 3.85Å; M250-F342 WeakPolarHBondContact O-CE1 3.13Å; M250-F342 VanDerWaalsContact O-CZ 3.29Å; M250-F342 WeakPolarHBondContact O-CZ 3.49Å; M250-F342 HydrophobicContact SD-CD2 4.09Å; M250-F342 HydrophobicContact SD-CE2 3.78Å; M250-L363 HydrophobicContact CG-CD1 4.18Å; M250-L363 HydrophobicContact CG-CD2 3.88Å
251	V	94.7	Very high	90.9	Very high	30 Å²	30	58.8 Å²	58.8	18%	0.182	30%	0.295	C	S	.	.	H	α-helix	trans	-63.3	-45	178.9	173.2	0	0	0	0	110.4	F247 T248 T255 I323	F247-V251 WeakPolarHBondContact O-CG2 3.34Å; F247-V251 PolarHBondContact O-N 3.47Å; T248-V251 PolarHBondContact O-N 3.07Å; V251-T255 VanDerWaalsContact O-CB 3.29Å; V251-T255 WeakPolarHBondContact O-CB 3.27Å; V251-T255 PolarHBondContact O-N 3.42Å; V251-T255 PolarHBondContact O-OG1 3.11Å; V251-I323 HydrophobicContact CG2-CB 4.13Å; V251-I323 HydrophobicContact CG2-CG1 4.2Å
252	V	94.5	Very high	90	Very high	81 Å²	81	57.7 Å²	57.7	49%	0.491	29%	0.287	S	S	.	.	H	α-helix	trans	-63.7	-48.2	179.3	172.1	0	0	0	0	111	T248 I249 T255 C256	T248-V252 HydrophobicContact CG2-CG2 4.32Å; T248-V252 WeakPolarHBondContact O-CB 3.36Å; T248-V252 VanDerWaalsContact O-CG2 3.24Å; T248-V252 WeakPolarHBondContact O-CG2 3.38Å; T248-V252 PolarHBondContact O-N 3Å; I249-V252 PolarHBondContact O-N 3.5Å; V252-T255 PolarHBondContact O-N 3.34Å; V252-C256 PolarHBondContact O-N 2.92Å; V252-C256 PolarHBondContact O-SG 3.28Å
253	W	92.1	Very high	88.7	Confident	76 Å²	76	62.4 Å²	62.4	29%	0.288	31%	0.308	S	S	.	.	H	α-helix	trans	-65.4	-45.3	-179.2	-170.6	-1.5	0	0	0	111.6	I249 M250 T255 C256 R257 F342 L345 I359 R360 L363	I249-W253 VanDerWaalsContact O-CB 3.26Å; I249-W253 WeakPolarHBondContact O-CB 3.16Å; I249-W253 PolarHBondContact O-N 2.89Å; M250-W253 PolarHBondContact O-N 2.87Å; W253-T255 VanDerWaalsContact C-N 3.33Å; W253-T255 PolarHBondContact O-N 3.48Å; W253-C256 PolarHBondContact O-N 3.45Å; W253-R257 WeakPolarHBondContact O-CB 3.31Å; W253-R257 PolarHBondContact O-N 3.07Å; W253-F342 HydrophobicContact CB-CD1 4.2Å; W253-F342 HydrophobicContact CB-CE1 3.87Å; W253-F342 AromaticContact CD2-CD1 3.65Å; W253-F342 HydrophobicContact CD2-CD1 3.65Å; W253-F342 HydrophobicContact CD2-CE1 4.22Å; W253-F342 HydrophobicContact CE3-CB 4.21Å; W253-F342 AromaticContact CE3-CD1 3.52Å; W253-F342 HydrophobicContact CE3-CD1 3.52Å; W253-F342 HydrophobicContact CE3-CE1 4.35Å; W253-F342 HydrophobicContact CE3-CG 4.25Å; W253-F342 AromaticContact CG-CD1 3.96Å; W253-F342 HydrophobicContact CG-CD1 3.96Å; W253-F342 HydrophobicContact CG-CE1 4.03Å; W253-F342 HydrophobicContact CH2-CB 4.47Å; W253-F342 HydrophobicContact CZ3-CB 3.97Å; W253-F342 HydrophobicContact CZ3-CD1 4.13Å; W253-F342 HydrophobicContact CZ3-CG 4.5Å; W253-L345 HydrophobicContact CH2-CD1 4.48Å; W253-L345 HydrophobicContact CZ2-CB 4.2Å; W253-L345 HydrophobicContact CZ2-CD1 3.73Å; W253-I359 HydrophobicContact CE3-CG2 4.32Å; W253-I359 HydrophobicContact CZ3-CG2 4Å; W253-R360 HydrophobicContact CH2-CG 3.78Å; W253-R360 HydrophobicContact CZ3-CG 4.2Å; W253-L363 HydrophobicContact CE3-CD1 4.11Å; W253-L363 HydrophobicContact CZ3-CD1 4.1Å
254	A	91.6	Very high	87.5	Confident	0 Å²	0	67.3 Å²	67.3	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-60.9	-41.5	174.5	0	0	0	0	0	112	M250 R257 A258 A330 F331 Y338 F342	M250-A254 WeakPolarHBondContact O-CB 3.37Å; M250-A254 PolarHBondContact O-N 2.96Å; A254-R257 PolarHBondContact O-N 3.29Å; A254-A258 VanDerWaalsContact O-CB 3.3Å; A254-A258 WeakPolarHBondContact O-CB 3.34Å; A254-A258 PolarHBondContact O-N 3.26Å; A254-A330 HydrophobicContact CB-CB 3.98Å; A254-A330 WeakPolarHBondContact O-CB 3.05Å; A254-F331 HydrophobicContact CB-CE2 4.35Å; A254-Y338 WeakPolarHBondContact CB-OH 3.07Å; A254-F342 HydrophobicContact CB-CE1 4.23Å; A254-F342 HydrophobicContact CB-CZ 4.04Å
255	T	92.7	Very high	85.8	Confident	60 Å²	60	67.9 Å²	67.9	37%	0.368	35%	0.353	S	S	.	.	H	α-helix	trans	-59.8	-49.5	174.7	-55	0	0	0	0	111.5	V251 V252 W253 R257 A258 V259 T326	V251-T255 VanDerWaalsContact O-CB 3.29Å; V251-T255 WeakPolarHBondContact O-CB 3.27Å; V251-T255 PolarHBondContact O-N 3.42Å; V251-T255 PolarHBondContact O-OG1 3.11Å; V252-T255 PolarHBondContact O-N 3.34Å; W253-T255 VanDerWaalsContact C-N 3.33Å; W253-T255 PolarHBondContact O-N 3.48Å; T255-R257 VanDerWaalsContact C-N 3.31Å; T255-R257 PolarHBondContact O-N 2.95Å; T255-A258 PolarHBondContact O-N 3.19Å; T255-V259 WeakPolarHBondContact O-CG2 3.15Å; T255-V259 PolarHBondContact O-N 3.19Å; T255-T326 WeakPolarHBondContact OG1-CG2 3.46Å
256	C	90.4	Very high	84.7	Confident	64 Å²	64	68 Å²	68	43%	0.432	37%	0.37	S	S	.	.	H	α-helix	trans	-58.7	-43.6	177.8	-70	0	0	0	0	111.8	V252 W253 V259 M260	V252-C256 PolarHBondContact O-N 2.92Å; V252-C256 PolarHBondContact O-SG 3.28Å; W253-C256 PolarHBondContact O-N 3.45Å; C256-V259 PolarHBondContact O-N 3.45Å; C256-M260 WeakPolarHBondContact O-CB 3.28Å; C256-M260 WeakPolarHBondContact O-CG 3.22Å; C256-M260 PolarHBondContact O-N 2.81Å
257	R	87	Confident	84.1	Confident	19 Å²	19	70.1 Å²	70.1	7%	0.072	38%	0.381	C	S	.	.	H	α-helix	trans	-64.6	-44.7	177.5	-173.3	-179.5	179.2	173.4	1.9	111.9	G185 W253 A254 T255 V259 M260 Y261 A330 L345	G185-R257 PolarHBondContact O-NH2 3.23Å; W253-R257 WeakPolarHBondContact O-CB 3.31Å; W253-R257 PolarHBondContact O-N 3.07Å; A254-R257 PolarHBondContact O-N 3.29Å; T255-R257 VanDerWaalsContact C-N 3.31Å; T255-R257 PolarHBondContact O-N 2.95Å; R257-V259 VanDerWaalsContact C-N 3.3Å; R257-V259 PolarHBondContact O-N 3.17Å; R257-M260 PolarHBondContact O-N 3.36Å; R257-Y261 HydrophobicContact CG-CD2 3.86Å; R257-Y261 PolarHBondContact O-N 3.16Å; R257-A330 HydrophobicContact CB-CB 4.22Å; R257-A330 WeakPolarHBondContact CD-O 3.12Å; R257-A330 HydrophobicContact CG-CB 4.38Å; R257-A330 PolarHBondContact NE-O 3.24Å; R257-L345 VanDerWaalsContact CZ-CD2 3.44Å
258	A	88.2	Confident	83.8	Confident	4 Å²	4	72.5 Å²	72.5	3%	0.033	39%	0.394	C	S	.	.	H	α-helix	trans	-58.9	-42.4	177	0	0	0	0	0	110.9	A254 T255 W262 M329 A330	A254-A258 VanDerWaalsContact O-CB 3.3Å; A254-A258 WeakPolarHBondContact O-CB 3.34Å; A254-A258 PolarHBondContact O-N 3.26Å; T255-A258 PolarHBondContact O-N 3.19Å; A258-W262 HydrophobicContact CB-CE3 4.24Å; A258-W262 HydrophobicContact CB-CZ3 4.41Å; A258-W262 VanDerWaalsContact O-CA 3.28Å; A258-W262 WeakPolarHBondContact O-CA 3.47Å; A258-W262 WeakPolarHBondContact O-CB 3.13Å; A258-W262 PolarHBondContact O-N 3.37Å; A258-W262 VanDerWaalsContact O-N 3.15Å; A258-M329 HydrophobicContact CB-CB 4Å; A258-A330 HydrophobicContact CB-CB 4.36Å
259	V	88.2	Confident	83.5	Confident	115 Å²	115	71.8 Å²	71.8	70%	0.697	39%	0.391	S	S	*	.	H	α-helix	trans	-67.2	-40.7	177.3	173	0	0	0	0	112.3	T255 C256 R257	T255-V259 WeakPolarHBondContact O-CG2 3.15Å; T255-V259 PolarHBondContact O-N 3.19Å; C256-V259 PolarHBondContact O-N 3.45Å; R257-V259 VanDerWaalsContact C-N 3.3Å; R257-V259 PolarHBondContact O-N 3.17Å
260	M	84.8	Confident	83.4	Confident	141 Å²	141	72.6 Å²	72.6	70%	0.695	40%	0.403	S	S	*	.	H	α-helix	trans	-77.9	-37.2	-175.6	-72.1	-178.8	178.4	0	0	114.1	C256 R257	C256-M260 WeakPolarHBondContact O-CB 3.28Å; C256-M260 WeakPolarHBondContact O-CG 3.22Å; C256-M260 PolarHBondContact O-N 2.81Å; R257-M260 PolarHBondContact O-N 3.36Å
261	Y	78.1	Confident	83.1	Confident	164 Å²	164	77.5 Å²	77.5	64%	0.643	42%	0.421	S	S	*	.	H	α-helix	trans	-119.4	20.4	-170.5	-58.1	-76	0	0	0	113.1	R257 H263	R257-Y261 HydrophobicContact CG-CD2 3.86Å; R257-Y261 PolarHBondContact O-N 3.16Å; Y261-H263 PolarHBondContact O-N 3.07Å
262	W	70.7	Confident	82.6	Confident	115 Å²	115	82.2 Å²	82.2	44%	0.436	45%	0.445	S	S	.	.			trans	-45.3	117.6	-174	-171.4	-96.8	0	0	0	112	A258 M329	A258-W262 HydrophobicContact CB-CE3 4.24Å; A258-W262 HydrophobicContact CB-CZ3 4.41Å; A258-W262 VanDerWaalsContact O-CA 3.28Å; A258-W262 WeakPolarHBondContact O-CA 3.47Å; A258-W262 WeakPolarHBondContact O-CB 3.13Å; A258-W262 PolarHBondContact O-N 3.37Å; A258-W262 VanDerWaalsContact O-N 3.15Å; W262-M329 HydrophobicContact CE3-CB 4.28Å; W262-M329 HydrophobicContact CH2-CB 4.11Å; W262-M329 HydrophobicContact CH2-CG 3.6Å; W262-M329 HydrophobicContact CH2-SD 3.26Å; W262-M329 WeakPolarHBondContact CH2-SD 3.36Å; W262-M329 HydrophobicContact CZ3-CB 3.56Å; W262-M329 HydrophobicContact CZ3-CE 4.18Å; W262-M329 HydrophobicContact CZ3-CG 3.57Å; W262-M329 HydrophobicContact CZ3-SD 3.36Å; W262-M329 WeakPolarHBondContact CZ3-SD 3.35Å
263	H	63.9	Low	81.9	Confident	133 Å²	133	83.8 Å²	83.8	62%	0.616	45%	0.45	S	S	*	.			trans	-126.6	107	172.2	-95.2	37.1	0	0	0	108.5	Y261 S265	Y261-H263 PolarHBondContact O-N 3.07Å; H263-S265 PolarHBondContact O-N 2.99Å
264	I	64.1	Low	81.4	Confident	125 Å²	125	82.7 Å²	82.7	64%	0.641	45%	0.448	S	S	*	.			trans	-61.9	-29.5	173.6	-60.3	175.9	0	0	0	110.3	G266 L267	I264-G266 PolarHBondContact O-N 3.33Å; I264-L267 PolarHBondContact O-N 3.22Å
265	S	56.3	Low	81	Confident	112 Å²	112	83.8 Å²	83.8	78%	0.783	45%	0.453	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.1	88.8	-178.7	-54.4	0	0	0	0	111.2	H263	H263-S265 PolarHBondContact O-N 2.99Å
266	G	70.9	Confident	80.7	Confident	68 Å²	68	81.1 Å²	81.1	70%	0.701	44%	0.436	S	S	*	.	T	Hydrogen-bonded Turn	trans	147.7	-14.8	175	0	0	0	0	0	115	I264 I268	I264-G266 PolarHBondContact O-N 3.33Å; G266-I268 PolarHBondContact O-N 3.31Å
267	L	81.9	Confident	80.6	Confident	45 Å²	45	79.1 Å²	79.1	24%	0.236	42%	0.421	C	S	.	.			trans	-72.9	122.5	177.8	-73.8	95.2	0	0	0	110.9	Y37 I264 V328 M329	Y37-L267 HydrophobicContact CD1-CB 4.27Å; Y37-L267 HydrophobicContact CD1-CD2 4.11Å; Y37-L267 HydrophobicContact CE1-CB 4.32Å; Y37-L267 HydrophobicContact CE1-CD2 4.49Å; I264-L267 PolarHBondContact O-N 3.22Å; L267-V328 HydrophobicContact CD2-CG1 4.1Å; L267-V328 HydrophobicContact CG-CG1 4.3Å; L267-M329 HydrophobicContact CD2-CG 4.23Å
268	I	86.8	Confident	80.9	Confident	50 Å²	50	78.2 Å²	78.2	26%	0.256	42%	0.418	S	S	.	.			trans	-85.5	124	173.1	-62.5	162	0	0	0	107.5	G36 Y37 G266 R271	G36-I268 CarbonylContact C-O 3.43Å; G36-I268 WeakPolarHBondContact CA-O 3.33Å; Y37-I268 WeakPolarHBondContact CD1-O 2.99Å; Y37-I268 PolarHBondContact N-O 3.08Å; Y37-I268 VanDerWaalsContact N-O 3.13Å; G266-I268 PolarHBondContact O-N 3.31Å; I268-R271 HydrophobicContact CG2-CB 4.18Å
269	P	88.3	Confident	81	Confident	68 Å²	68	78 Å²	78	44%	0.442	42%	0.416	S	S	.	.	S	Bend	trans	-70.4	-48.4	179.8	24.3	-31.5	0	0	0	112.2	G36 Y37 I38	G36-P269 CarbonylContact C-O 3.47Å; Y37-P269 HydrophobicContact CE1-CB 4.23Å; Y37-P269 PolarHBondContact N-O 3.21Å; I38-P269 VanDerWaalsContact CB-O 3.31Å; I38-P269 WeakPolarHBondContact CB-O 3.5Å; I38-P269 HydrophobicContact CD1-CB 3.83Å; I38-P269 HydrophobicContact CG1-CB 4.32Å; I38-P269 PolarHBondContact N-O 3Å
270	A	91.3	Very high	81.3	Confident	55 Å²	55	72.5 Å²	72.5	46%	0.455	38%	0.383	S	S	.	.			trans	-158	136.2	176.9	0	0	0	0	0	110.4	A35 L39	A35-A270 CarbonylContact O-C 3.3Å; A35-A270 WeakPolarHBondContact O-CA 3.32Å; L39-A270 HydrophobicContact CB-CB 4.02Å
271	R	88.5	Confident	81.7	Confident	102 Å²	102	65.8 Å²	65.8	39%	0.385	35%	0.35	S	S	.	.			trans	-133.7	106.6	169.9	-177.8	-176.2	-66	175.4	-0.2	108	A35 I268 D273 Q274	A35-R271 PolarHBondContact O-N 3.27Å; I268-R271 HydrophobicContact CG2-CB 4.18Å; R271-D273 HydrophobicContact CG-CB 4.2Å; R271-D273 PolarHBondContact O-N 3.33Å; R271-Q274 HydrophobicContact CG-CG 4.47Å; R271-Q274 PolarHBondContact O-N 3.12Å
272	I	83.7	Confident	82.5	Confident	130 Å²	130	58 Å²	58	67%	0.667	32%	0.32	S	S	*	.	G	3₁₀ helix	trans	-68	-30.2	-174.8	-59.3	175.3	0	0	0	110.8	Q274 F275	I272-Q274 PolarHBondContact O-N 3.27Å; I272-F275 WeakPolarHBondContact O-CB 3.45Å; I272-F275 PolarHBondContact O-N 2.92Å
273	D	81.5	Confident	83.7	Confident	113 Å²	113	52.5 Å²	52.5	60%	0.604	30%	0.299	S	S	*	.	G	3₁₀ helix	trans	-58.3	-32.8	179.9	-46.7	-28.3	0	0	0	112.3	R271	R271-D273 HydrophobicContact CG-CB 4.2Å; R271-D273 PolarHBondContact O-N 3.33Å
274	Q	80.2	Confident	85.2	Confident	53 Å²	53	46.8 Å²	46.8	25%	0.248	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-96.9	17	179.6	-67.4	-66.8	-12	0	0	113.1	D34 R271 I272 T276 N277	D34-Q274 HydrophobicContact CB-CB 4.12Å; D34-Q274 HydrophobicContact CB-CG 4.24Å; R271-Q274 HydrophobicContact CG-CG 4.47Å; R271-Q274 PolarHBondContact O-N 3.12Å; I272-Q274 PolarHBondContact O-N 3.27Å; Q274-T276 PolarHBondContact O-N 3.34Å; Q274-N277 PolarHBondContact OE1-ND2 3.21Å
275	F	83.7	Confident	86.7	Confident	23 Å²	23	41 Å²	41	10%	0.101	24%	0.242	C	C	.	.	H	α-helix	trans	-60	-34.7	179.4	174.5	-93.4	0	0	0	112.6	L39 V43 I272 N277 L278 F279 I528	L39-F275 HydrophobicContact CD1-CD2 4.42Å; L39-F275 HydrophobicContact CD2-CD2 4.33Å; V43-F275 HydrophobicContact CG1-CE2 4.38Å; V43-F275 HydrophobicContact CG2-CD2 4.24Å; V43-F275 HydrophobicContact CG2-CE2 3.67Å; I272-F275 WeakPolarHBondContact O-CB 3.45Å; I272-F275 PolarHBondContact O-N 2.92Å; F275-N277 PolarHBondContact O-N 3.43Å; F275-L278 PolarHBondContact O-N 3.03Å; F275-F279 HydrophobicContact CD1-CB 4.17Å; F275-F279 HydrophobicContact CE1-CB 3.84Å; F275-F279 HydrophobicContact CE1-CD2 4.15Å; F275-F279 HydrophobicContact CE1-CG 4.05Å; F275-F279 HydrophobicContact CZ-CB 4.15Å; F275-F279 HydrophobicContact CZ-CD2 4.07Å; F275-F279 HydrophobicContact CZ-CG 4.36Å; F275-F279 WeakPolarHBondContact O-CB 3.28Å; F275-F279 PolarHBondContact O-N 3.42Å; F275-I528 HydrophobicContact CD1-CG2 3.56Å; F275-I528 HydrophobicContact CE1-CD1 4.36Å; F275-I528 HydrophobicContact CE1-CG2 3.77Å
276	T	86.6	Confident	88.5	Confident	4 Å²	4	35.6 Å²	35.6	3%	0.025	21%	0.205	C	C	.	.	H	α-helix	trans	-56.8	-48.7	-177.3	-63.6	0	0	0	0	112.5	Q274 F279 G280 S468 V529 N532	Q274-T276 PolarHBondContact O-N 3.34Å; T276-F279 PolarHBondContact O-N 2.89Å; T276-G280 PolarHBondContact O-N 2.92Å; T276-S468 PolarHBondContact O-OG 3.08Å; T276-V529 HydrophobicContact CG2-CB 4.18Å; T276-V529 HydrophobicContact CG2-CG1 3.61Å; T276-V529 HydrophobicContact CG2-CG2 4.05Å; T276-N532 WeakPolarHBondContact OG1-CB 3.39Å; T276-N532 PolarHBondContact OG1-ND2 3.45Å
277	N	88.5	Confident	89.5	Confident	22 Å²	22	32.7 Å²	32.7	12%	0.118	17%	0.173	C	C	.	.	H	α-helix	trans	-67.4	-42.6	-177.3	-69.6	-10.7	0	0	0	112.1	Q274 F275 F279 T281 E464 S468	Q274-N277 PolarHBondContact OE1-ND2 3.21Å; F275-N277 PolarHBondContact O-N 3.43Å; N277-F279 VanDerWaalsContact C-N 3.34Å; N277-F279 PolarHBondContact O-N 2.8Å; N277-T281 WeakPolarHBondContact O-CB 3.28Å; N277-T281 PolarHBondContact O-N 3.49Å; N277-T281 PolarHBondContact O-OG1 3.38Å; N277-E464 HydrophobicContact CB-CG 4.15Å; N277-E464 WeakPolarHBondContact CB-OE1 3.38Å; N277-S468 WeakPolarHBondContact CA-OG 3.46Å; N277-S468 PolarHBondContact OD1-OG 3.04Å
278	L	92.5	Very high	90.1	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-59.5	-46	172.8	175.9	65.7	0	0	0	111.8	A31 F32 A35 L39 V43 F275 S282	A31-L278 HydrophobicContact CB-CB 4.48Å; A31-L278 HydrophobicContact CB-CD1 4.4Å; F32-L278 HydrophobicContact CD2-CD1 3.61Å; F32-L278 HydrophobicContact CE2-CD1 3.7Å; A35-L278 HydrophobicContact CB-CB 3.64Å; A35-L278 HydrophobicContact CB-CD2 3.61Å; A35-L278 HydrophobicContact CB-CG 4.17Å; L39-L278 HydrophobicContact CG-CD2 4.02Å; V43-L278 HydrophobicContact CB-CD2 3.94Å; V43-L278 HydrophobicContact CB-CG 4.42Å; V43-L278 HydrophobicContact CG1-CD2 4.19Å; V43-L278 HydrophobicContact CG1-CG 4.18Å; V43-L278 HydrophobicContact CG2-CD2 4.13Å; F275-L278 PolarHBondContact O-N 3.03Å; L278-S282 WeakPolarHBondContact O-CB 3.46Å; L278-S282 PolarHBondContact O-N 3.46Å; L278-S282 PolarHBondContact O-OG 3.25Å
279	F	91.6	Very high	90.4	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-63.7	-55	-178.4	171.9	-95.7	0	0	0	111.9	I47 F275 T276 N277 T281 S282 I283 V476 W521 S525 V529	I47-F279 HydrophobicContact CD1-CD2 3.82Å; I47-F279 HydrophobicContact CD1-CE2 4.19Å; F275-F279 HydrophobicContact CD1-CB 4.17Å; F275-F279 HydrophobicContact CE1-CB 3.84Å; F275-F279 HydrophobicContact CE1-CD2 4.15Å; F275-F279 HydrophobicContact CE1-CG 4.05Å; F275-F279 HydrophobicContact CZ-CB 4.15Å; F275-F279 HydrophobicContact CZ-CD2 4.07Å; F275-F279 HydrophobicContact CZ-CG 4.36Å; F275-F279 WeakPolarHBondContact O-CB 3.28Å; F275-F279 PolarHBondContact O-N 3.42Å; T276-F279 PolarHBondContact O-N 2.89Å; N277-F279 VanDerWaalsContact C-N 3.34Å; N277-F279 PolarHBondContact O-N 2.8Å; F279-T281 PolarHBondContact O-N 2.9Å; F279-S282 PolarHBondContact O-N 3.44Å; F279-I283 HydrophobicContact CD1-CD1 4.34Å; F279-I283 HydrophobicContact CD2-CD1 4.41Å; F279-I283 HydrophobicContact CE1-CD1 3.5Å; F279-I283 VanDerWaalsContact CE1-CD1 3.5Å; F279-I283 HydrophobicContact CE1-CG1 4.47Å; F279-I283 HydrophobicContact CE2-CD1 3.56Å; F279-I283 HydrophobicContact CE2-CG1 4.21Å; F279-I283 HydrophobicContact CZ-CD1 3Å; F279-I283 HydrophobicContact CZ-CG1 4.04Å; F279-I283 PolarHBondContact O-N 2.89Å; F279-V476 HydrophobicContact CE1-CG2 4.22Å; F279-V476 HydrophobicContact CZ-CG2 4.1Å; F279-W521 HydrophobicContact CD2-CZ2 4.2Å; F279-W521 HydrophobicContact CE2-CH2 4.49Å; F279-W521 AromaticContact CE2-CZ2 3.69Å; F279-W521 HydrophobicContact CE2-CZ2 3.69Å; F279-S525 WeakPolarHBondContact CE2-OG 3.34Å; F279-S525 WeakPolarHBondContact CZ-OG 3.34Å; F279-V529 HydrophobicContact CD1-CG2 3.48Å; F279-V529 VanDerWaalsContact CD1-CG2 3.48Å; F279-V529 HydrophobicContact CE1-CG2 3.83Å; F279-V529 HydrophobicContact CG-CG2 4.47Å
280	G	92.8	Very high	90.4	Very high	0 Å²	0	26.7 Å²	26.7	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-61.3	-44.3	-178.7	0	0	0	0	0	112.3	T276 S282 I283 Y284 S468 S472	T276-G280 PolarHBondContact O-N 2.92Å; G280-S282 VanDerWaalsContact C-N 3.34Å; G280-S282 PolarHBondContact O-N 2.86Å; G280-I283 PolarHBondContact O-N 2.9Å; G280-Y284 WeakPolarHBondContact O-CB 3.02Å; G280-Y284 PolarHBondContact O-N 3.37Å; G280-S468 WeakPolarHBondContact CA-O 3.49Å; G280-S472 WeakPolarHBondContact CA-OG 3.33Å
281	T	94.4	Very high	90.1	Very high	0 Å²	0	26 Å²	26	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-63.5	-38.8	176.9	-56.1	0	0	0	0	112.3	A27 L28 A31 N277 F279 S285 I467	A27-T281 HydrophobicContact CB-CG2 3.87Å; L28-T281 HydrophobicContact CD2-CG2 3.82Å; L28-T281 HydrophobicContact CG-CG2 4.07Å; A31-T281 HydrophobicContact CB-CG2 4.42Å; N277-T281 WeakPolarHBondContact O-CB 3.28Å; N277-T281 PolarHBondContact O-N 3.49Å; N277-T281 PolarHBondContact O-OG1 3.38Å; F279-T281 PolarHBondContact O-N 2.9Å; T281-S285 WeakPolarHBondContact O-CB 3.07Å; T281-S285 PolarHBondContact O-N 3.41Å; T281-S285 PolarHBondContact O-OG 3.35Å; T281-I467 HydrophobicContact CG2-CG2 3.93Å
282	S	95.3	Very high	90	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-67.5	-41.6	177.1	-64.2	0	0	0	0	112.4	L44 L278 F279 G280 S285 F286	L44-S282 WeakPolarHBondContact CD1-OG 3.49Å; L278-S282 WeakPolarHBondContact O-CB 3.46Å; L278-S282 PolarHBondContact O-N 3.46Å; L278-S282 PolarHBondContact O-OG 3.25Å; F279-S282 PolarHBondContact O-N 3.44Å; G280-S282 VanDerWaalsContact C-N 3.34Å; G280-S282 PolarHBondContact O-N 2.86Å; S282-S285 PolarHBondContact O-N 3.1Å; S282-F286 WeakPolarHBondContact O-CD2 3.3Å; S282-F286 PolarHBondContact O-N 2.99Å
283	I	94.8	Very high	89.8	Confident	0 Å²	0	15.4 Å²	15.4	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-62.2	-51.3	174.8	-72.7	-173.2	0	0	0	110.4	I47 F279 G280 S285 F286 M287 G471 V476 Q479 Y480	I47-I283 HydrophobicContact CD1-CG1 4.25Å; I47-I283 HydrophobicContact CG2-CG1 4.16Å; F279-I283 HydrophobicContact CD1-CD1 4.34Å; F279-I283 HydrophobicContact CD2-CD1 4.41Å; F279-I283 HydrophobicContact CE1-CD1 3.5Å; F279-I283 VanDerWaalsContact CE1-CD1 3.5Å; F279-I283 HydrophobicContact CE1-CG1 4.47Å; F279-I283 HydrophobicContact CE2-CD1 3.56Å; F279-I283 HydrophobicContact CE2-CG1 4.21Å; F279-I283 HydrophobicContact CZ-CD1 3Å; F279-I283 HydrophobicContact CZ-CG1 4.04Å; F279-I283 PolarHBondContact O-N 2.89Å; G280-I283 PolarHBondContact O-N 2.9Å; I283-S285 PolarHBondContact O-N 3.08Å; I283-F286 PolarHBondContact O-N 3.02Å; I283-M287 PolarHBondContact O-N 3.39Å; I283-G471 WeakPolarHBondContact CG2-O 3.34Å; I283-V476 HydrophobicContact CD1-CG2 3.49Å; I283-V476 VanDerWaalsContact CD1-CG2 3.49Å; I283-Q479 PolarHBondContact O-OE1 2.99Å; I283-Q479 VanDerWaalsContact O-OE1 3.11Å; I283-Y480 HydrophobicContact CD1-CD2 4.41Å; I283-Y480 HydrophobicContact CD1-CE2 3.49Å; I283-Y480 VanDerWaalsContact CD1-CE2 3.49Å; I283-Y480 HydrophobicContact CG1-CE2 4.18Å
284	Y	95.1	Very high	89.7	Confident	12 Å²	12	12.1 Å²	12.1	5%	0.047	7%	0.074	C	C	.	.	H	α-helix	trans	-53.6	-39.7	178.1	-176.9	-93.3	0	0	0	111.7	T23 Y151 D155 I158 G280 F286 M287 I467 T470	T23-Y284 WeakPolarHBondContact OG1-CE1 3.38Å; T23-Y284 PolarHBondContact OG1-OH 2.98Å; Y151-Y284 AromaticContact CE2-CD2 3.78Å; Y151-Y284 HydrophobicContact CE2-CD2 3.78Å; Y151-Y284 AromaticContact CE2-CE2 3.88Å; Y151-Y284 HydrophobicContact CE2-CE2 3.88Å; Y151-Y284 AromaticContact CZ-CE2 4Å; D155-Y284 WeakPolarHBondContact OD1-CE2 3.39Å; D155-Y284 PolarHBondContact OD1-OH 3.39Å; I158-Y284 HydrophobicContact CD1-CE2 3.8Å; G280-Y284 WeakPolarHBondContact O-CB 3.02Å; G280-Y284 PolarHBondContact O-N 3.37Å; Y284-F286 PolarHBondContact O-N 3.14Å; Y284-M287 WeakPolarHBondContact O-CB 3.25Å; Y284-M287 PolarHBondContact O-N 3.29Å; Y284-I467 HydrophobicContact CD1-CG1 4.5Å; Y284-I467 HydrophobicContact CD1-CG2 3.72Å; Y284-I467 HydrophobicContact CE1-CG1 4.44Å; Y284-I467 HydrophobicContact CE1-CG2 4.46Å; Y284-I467 HydrophobicContact CG-CG2 3.83Å; Y284-T470 HydrophobicContact CD2-CG2 4.07Å; Y284-T470 HydrophobicContact CE2-CG2 4.07Å
285	S	95.5	Very high	89.9	Confident	3 Å²	3	10.3 Å²	10.3	2%	0.021	7%	0.066	C	C	.	.	H	α-helix	trans	-71.3	-24.1	-179.5	-59.3	0	0	0	0	114.8	G24 T281 S282 I283 Y320	G24-S285 VanDerWaalsContact C-OG 3.24Å; G24-S285 WeakPolarHBondContact CA-OG 3.48Å; G24-S285 PolarHBondContact O-OG 3.29Å; T281-S285 WeakPolarHBondContact O-CB 3.07Å; T281-S285 PolarHBondContact O-N 3.41Å; T281-S285 PolarHBondContact O-OG 3.35Å; S282-S285 PolarHBondContact O-N 3.1Å; I283-S285 PolarHBondContact O-N 3.08Å; S285-Y320 WeakPolarHBondContact O-CE2 3.34Å; S285-Y320 PolarHBondContact O-OH 3.21Å
286	F	95.5	Very high	89.9	Confident	0 Å²	0	9.3 Å²	9.3	0%	0	6%	0.062	C	C	.	.	T	Hydrogen-bonded Turn	trans	-106.6	12.9	179.7	-79.9	-68.5	0	0	0	113.6	L20 L44 I47 S51 S282 I283 Y284 C288 Y313 V316 L317 Y320	L20-F286 HydrophobicContact CD2-CD1 4.47Å; L44-F286 HydrophobicContact CD1-CD2 4.28Å; L44-F286 HydrophobicContact CD1-CE2 3.61Å; L44-F286 HydrophobicContact CG-CE2 3.98Å; I47-F286 HydrophobicContact CG2-CD2 4.08Å; S51-F286 PolarHBondContact OG-O 3.03Å; S282-F286 WeakPolarHBondContact O-CD2 3.3Å; S282-F286 PolarHBondContact O-N 2.99Å; I283-F286 PolarHBondContact O-N 3.02Å; Y284-F286 PolarHBondContact O-N 3.14Å; F286-C288 PolarHBondContact O-N 3.29Å; F286-Y313 AromaticContact CD1-CD1 3.86Å; F286-Y313 HydrophobicContact CD1-CD1 3.86Å; F286-Y313 AromaticContact CD1-CE1 3.76Å; F286-Y313 HydrophobicContact CD1-CE1 3.76Å; F286-Y313 HydrophobicContact CE1-CD1 4.08Å; F286-Y313 HydrophobicContact CE1-CE1 4.44Å; F286-V316 HydrophobicContact CD1-CG1 4.34Å; F286-V316 HydrophobicContact CE1-CB 4.32Å; F286-V316 HydrophobicContact CE1-CG1 3.72Å; F286-V316 HydrophobicContact CZ-CG1 4.39Å; F286-L317 HydrophobicContact CZ-CB 4.19Å; F286-L317 HydrophobicContact CZ-CD1 4.21Å; F286-Y320 HydrophobicContact CD1-CE2 4.32Å; F286-Y320 HydrophobicContact CD2-CD2 4.42Å; F286-Y320 HydrophobicContact CD2-CE2 4.36Å; F286-Y320 HydrophobicContact CE1-CD2 4.1Å; F286-Y320 HydrophobicContact CE1-CE2 4.06Å; F286-Y320 AromaticContact CE2-CD2 3.76Å; F286-Y320 HydrophobicContact CE2-CD2 3.76Å; F286-Y320 HydrophobicContact CE2-CE2 4.11Å; F286-Y320 HydrophobicContact CG-CE2 4.46Å; F286-Y320 AromaticContact CZ-CD2 3.56Å; F286-Y320 HydrophobicContact CZ-CD2 3.56Å; F286-Y320 AromaticContact CZ-CE2 3.94Å; F286-Y320 HydrophobicContact CZ-CE2 3.94Å
287	M	92	Very high	89.6	Confident	6 Å²	6	9.6 Å²	9.6	3%	0.03	6%	0.064	C	C	.	.			trans	-80.4	118.4	-176.6	178.2	53.4	163.1	0	0	111	Y151 I283 Y284 H290 I478 Q479	Y151-M287 HydrophobicContact CD1-CE 4.3Å; Y151-M287 HydrophobicContact CD2-CE 4.12Å; Y151-M287 HydrophobicContact CE1-CE 4.26Å; Y151-M287 HydrophobicContact CE1-CG 4.22Å; Y151-M287 HydrophobicContact CE2-CB 4.4Å; Y151-M287 HydrophobicContact CE2-CE 4.09Å; Y151-M287 HydrophobicContact CE2-CG 3.69Å; Y151-M287 HydrophobicContact CG-CE 4.23Å; Y151-M287 VanDerWaalsContact CZ-CG 3.49Å; Y151-M287 VanDerWaalsContact OH-CG 3.3Å; Y151-M287 WeakPolarHBondContact OH-CG 3.47Å; I283-M287 PolarHBondContact O-N 3.39Å; Y284-M287 WeakPolarHBondContact O-CB 3.25Å; Y284-M287 PolarHBondContact O-N 3.29Å; M287-H290 WeakPolarHBondContact CE-ND1 3.12Å; M287-I478 HydrophobicContact CE-CB 3.38Å; M287-I478 HydrophobicContact CE-CD1 3.39Å; M287-I478 HydrophobicContact CE-CG1 3.98Å; M287-I478 HydrophobicContact CE-CG2 3.47Å; M287-I478 VanDerWaalsContact CE-CG2 3.47Å; M287-I478 HydrophobicContact SD-CB 4.4Å; M287-I478 HydrophobicContact SD-CG2 4.39Å; M287-Q479 HydrophobicContact SD-CB 4.04Å
288	C	92.5	Very high	89.2	Confident	0 Å²	0	8.9 Å²	8.9	0%	0	6%	0.06	C	C	.	.			trans	-145.8	-9.8	176.1	66.4	0	0	0	0	114.6	L16 L19 L20 F286 H290 S291 L292 Y313	L16-C288 HydrophobicContact CD1-CB 4.02Å; L19-C288 HydrophobicContact CD2-CB 3.7Å; L19-C288 HydrophobicContact CG-CB 4.41Å; L20-C288 HydrophobicContact CD2-CB 3.83Å; L20-C288 HydrophobicContact CG-CB 4.3Å; F286-C288 PolarHBondContact O-N 3.29Å; C288-H290 VanDerWaalsContact C-N 3.29Å; C288-H290 PolarHBondContact O-N 2.85Å; C288-H290 VanDerWaalsContact O-N 3.16Å; C288-S291 PolarHBondContact O-N 2.69Å; C288-L292 PolarHBondContact O-N 2.98Å; C288-Y313 PolarHBondContact SG-OH 3.4Å
289	H	93.1	Very high	88.8	Confident	0 Å²	0	8.9 Å²	8.9	0%	0	6%	0.06	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.2	-35.6	-164.4	-60.9	60	0	0	0	113.6	S51 M55 V58 L292	S51-H289 PolarHBondContact O-CE1 2.85Å; S51-H289 PolarHBondContact O-NE2 2.75Å; S51-H289 PolarHBondContact OG-CE1 2.81Å; M55-H289 WeakPolarHBondContact CA-NE2 3.43Å; M55-H289 PolarHBondContact N-NE2 3.42Å; V58-H289 HydrophobicContact CG2-CB 4.22Å; H289-L292 WeakPolarHBondContact O-CB 3.43Å
290	H	88.7	Confident	88.2	Confident	37 Å²	37	15 Å²	15	17%	0.171	9%	0.087	C	C	.	.	T	Hydrogen-bonded Turn	trans	-70.4	-30.2	179.8	64.5	-85.6	0	0	0	114.1	M148 Y151 M287 C288 I478	M148-H290 HydrophobicContact CE-CB 3.73Å; M148-H290 HydrophobicContact SD-CB 3.35Å; M148-H290 WeakPolarHBondContact SD-CB 3.28Å; Y151-H290 AromaticContact CE1-CE1 3.82Å; M287-H290 WeakPolarHBondContact CE-ND1 3.12Å; C288-H290 VanDerWaalsContact C-N 3.29Å; C288-H290 PolarHBondContact O-N 2.85Å; C288-H290 VanDerWaalsContact O-N 3.16Å; H290-I478 HydrophobicContact CB-CG2 3.96Å
291	S	86.6	Confident	87.5	Confident	42 Å²	42	19.1 Å²	19.1	29%	0.294	11%	0.112	S	C	.	.	T	Hydrogen-bonded Turn	trans	-93.1	-8.5	-177.4	-74	0	0	0	0	112.6	C288 P293 G294	C288-S291 PolarHBondContact O-N 2.69Å; S291-P293 VanDerWaalsContact C-CD 3.48Å; S291-G294 PolarHBondContact O-N 2.7Å; S291-G294 VanDerWaalsContact O-N 3.12Å
292	L	84.8	Confident	86.7	Confident	1 Å²	1	19.7 Å²	19.7	1%	0.005	11%	0.114	C	C	.	.	H	α-helix	trans	-57.6	-42.4	-173.4	-166.9	73.5	0	0	0	115	L16 M55 V58 V59 C288 H289 G294 I295 I296	L16-L292 HydrophobicContact CD1-CD1 4.2Å; M55-L292 HydrophobicContact CE-CD1 3.55Å; M55-L292 HydrophobicContact CE-CD2 3.76Å; M55-L292 HydrophobicContact CE-CG 4.18Å; M55-L292 HydrophobicContact CG-CD1 4.3Å; M55-L292 HydrophobicContact CG-CD2 4.01Å; M55-L292 HydrophobicContact SD-CD2 4.44Å; V58-L292 HydrophobicContact CB-CD2 3.87Å; V58-L292 HydrophobicContact CG1-CD2 3.73Å; V59-L292 HydrophobicContact CG2-CD2 3.84Å; C288-L292 PolarHBondContact O-N 2.98Å; H289-L292 WeakPolarHBondContact O-CB 3.43Å; L292-G294 PolarHBondContact O-N 3.05Å; L292-I295 PolarHBondContact O-N 3.24Å; L292-I296 HydrophobicContact CD1-CD1 3.66Å; L292-I296 HydrophobicContact CD1-CG1 4.01Å; L292-I296 HydrophobicContact CD2-CD1 3.72Å; L292-I296 HydrophobicContact CG-CD1 3.44Å; L292-I296 VanDerWaalsContact CG-CD1 3.44Å; L292-I296 HydrophobicContact CG-CG1 3.99Å; L292-I296 PolarHBondContact O-N 3.04Å
293	P	79.7	Confident	85.9	Confident	7 Å²	7	29 Å²	29	5%	0.045	15%	0.149	C	C	.	.	H	α-helix	trans	-58.6	-37.3	177	-18	26.9	0	0	0	112.6	L62 I126 L128 S291 I295 T297	L62-P293 HydrophobicContact CD1-CB 4.06Å; L62-P293 HydrophobicContact CD1-CG 3.8Å; L62-P293 HydrophobicContact CD2-CB 4.31Å; L62-P293 HydrophobicContact CD2-CG 3.98Å; I126-P293 WeakPolarHBondContact O-CB 3.31Å; L128-P293 HydrophobicContact CB-CG 4.05Å; S291-P293 VanDerWaalsContact C-CD 3.48Å; P293-I295 PolarHBondContact O-N 3.22Å; P293-T297 VanDerWaalsContact O-CB 3.3Å; P293-T297 WeakPolarHBondContact O-CB 3.2Å; P293-T297 PolarHBondContact O-N 3.29Å; P293-T297 PolarHBondContact O-OG1 3.18Å
294	G	79.3	Confident	85.5	Confident	44 Å²	44	33.7 Å²	33.7	45%	0.454	18%	0.175	S	C	.	.	H	α-helix	trans	-65.5	-21.8	177.8	0	0	0	0	0	113.8	S291 L292 P298	S291-G294 PolarHBondContact O-N 2.7Å; S291-G294 VanDerWaalsContact O-N 3.12Å; L292-G294 PolarHBondContact O-N 3.05Å; G294-P298 WeakPolarHBondContact O-CD 3.41Å; G294-P298 WeakPolarHBondContact O-CG 3.25Å
295	I	84	Confident	85.2	Confident	16 Å²	16	33.2 Å²	33.2	8%	0.082	17%	0.173	C	C	.	.	H	α-helix	trans	-95	-46.8	179	-59.6	175.7	0	0	0	110.9	Y7 G12 L16 L19 L292 P293 P298 M299	Y7-I295 VanDerWaalsContact OH-CA 3.31Å; Y7-I295 WeakPolarHBondContact OH-CA 3.4Å; Y7-I295 PolarHBondContact OH-O 2.88Å; G12-I295 WeakPolarHBondContact O-CG2 3.33Å; L16-I295 HydrophobicContact CB-CD1 4.48Å; L16-I295 HydrophobicContact CD1-CD1 4.39Å; L19-I295 HydrophobicContact CD2-CD1 3.83Å; L292-I295 PolarHBondContact O-N 3.24Å; P293-I295 PolarHBondContact O-N 3.22Å; I295-P298 WeakPolarHBondContact O-CD 3.33Å; I295-M299 WeakPolarHBondContact O-CG 3.41Å
296	I	84.5	Confident	85.1	Confident	2 Å²	2	34.2 Å²	34.2	1%	0.01	18%	0.176	C	C	.	.	H	α-helix	trans	-76.7	-44.5	-171.7	-65.5	-178.6	0	0	0	112.6	M55 V59 M122 L292 M299 K302 I305	M55-I296 HydrophobicContact CE-CD1 3.83Å; V59-I296 HydrophobicContact CG2-CD1 3.48Å; V59-I296 VanDerWaalsContact CG2-CD1 3.48Å; M122-I296 HydrophobicContact CE-CG2 3.46Å; M122-I296 VanDerWaalsContact CE-CG2 3.46Å; M122-I296 HydrophobicContact SD-CG2 4.07Å; L292-I296 HydrophobicContact CD1-CD1 3.66Å; L292-I296 HydrophobicContact CD1-CG1 4.01Å; L292-I296 HydrophobicContact CD2-CD1 3.72Å; L292-I296 HydrophobicContact CG-CD1 3.44Å; L292-I296 VanDerWaalsContact CG-CD1 3.44Å; L292-I296 HydrophobicContact CG-CG1 3.99Å; L292-I296 PolarHBondContact O-N 3.04Å; I296-M299 HydrophobicContact CG1-SD 4.46Å; I296-M299 VanDerWaalsContact O-CB 3.3Å; I296-M299 WeakPolarHBondContact O-CB 3.06Å; I296-M299 PolarHBondContact O-N 2.81Å; I296-K302 HydrophobicContact CG2-CD 4.33Å; I296-K302 WeakPolarHBondContact O-CE 3.31Å; I296-I305 HydrophobicContact CB-CD1 4.25Å; I296-I305 HydrophobicContact CD1-CD1 3.63Å; I296-I305 HydrophobicContact CG1-CD1 3.87Å; I296-I305 HydrophobicContact CG2-CD1 3.43Å; I296-I305 VanDerWaalsContact CG2-CD1 3.43Å
297	T	80	Confident	84.9	Confident	10 Å²	10	40.3 Å²	40.3	6%	0.061	21%	0.205	C	C	.	.	T	Hydrogen-bonded Turn	trans	-53.4	-47.4	-176.7	-58.6	0	0	0	0	113.4	M122 E124 R125 P293 M299	M122-T297 WeakPolarHBondContact O-CG2 3.37Å; E124-T297 VanDerWaalsContact C-CG2 3.47Å; E124-T297 WeakPolarHBondContact O-CG2 3.44Å; R125-T297 HydrophobicContact CB-CG2 4.34Å; R125-T297 HydrophobicContact CG-CG2 3.61Å; P293-T297 VanDerWaalsContact O-CB 3.3Å; P293-T297 WeakPolarHBondContact O-CB 3.2Å; P293-T297 PolarHBondContact O-N 3.29Å; P293-T297 PolarHBondContact O-OG1 3.18Å; T297-M299 PolarHBondContact O-N 2.81Å
298	P	80.9	Confident	85	Confident	6 Å²	6	42.6 Å²	42.6	4%	0.039	22%	0.217	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.5	2.4	179.2	30.9	-37.9	0	0	0	115.3	Q6 Y7 G294 I295	Q6-P298 CarbonylContact C-O 3.58Å; Q6-P298 VanDerWaalsContact CA-O 3.23Å; Q6-P298 WeakPolarHBondContact CA-O 3.47Å; Y7-P298 HydrophobicContact CD1-CB 4.07Å; Y7-P298 HydrophobicContact CD1-CG 4.25Å; Y7-P298 HydrophobicContact CE1-CB 3.66Å; Y7-P298 HydrophobicContact CE1-CG 3.36Å; Y7-P298 HydrophobicContact CE2-CG 4.42Å; Y7-P298 PolarHBondContact N-O 3.49Å; Y7-P298 WeakPolarHBondContact OH-CG 3.19Å; G294-P298 WeakPolarHBondContact O-CD 3.41Å; G294-P298 WeakPolarHBondContact O-CG 3.25Å; I295-P298 WeakPolarHBondContact O-CD 3.33Å
299	M	83.6	Confident	85	Confident	1 Å²	1	42.6 Å²	42.6	1%	0.005	22%	0.217	C	C	.	.	B	Isolated β-bridge	trans	-74	127.4	175.7	-69.6	168.2	62.3	0	0	111.3	Y7 A9 M13 I295 I296 T297 T301 K302	Y7-M299 HydrophobicContact CD2-CG 4.17Å; Y7-M299 HydrophobicContact CE2-CG 3.61Å; Y7-M299 WeakPolarHBondContact O-CA 3.38Å; A9-M299 HydrophobicContact CB-CE 3.59Å; M13-M299 HydrophobicContact CE-CE 3.66Å; M13-M299 HydrophobicContact CE-SD 3.91Å; I295-M299 WeakPolarHBondContact O-CG 3.41Å; I296-M299 HydrophobicContact CG1-SD 4.46Å; I296-M299 VanDerWaalsContact O-CB 3.3Å; I296-M299 WeakPolarHBondContact O-CB 3.06Å; I296-M299 PolarHBondContact O-N 2.81Å; T297-M299 PolarHBondContact O-N 2.81Å; M299-T301 PolarHBondContact O-N 3.06Å; M299-K302 PolarHBondContact O-NZ 3Å; M299-K302 VanDerWaalsContact O-NZ 3.1Å
300	K	78.5	Confident	85.1	Confident	129 Å²	129	44 Å²	44	56%	0.561	23%	0.228	S	C	*	.	S	Bend	trans	-58.3	-45.8	177.5	-71	-173.6	176.6	-169.9	0	112.9	Q6 Y7	Q6-K300 HydrophobicContact CB-CD 4.41Å; Q6-K300 HydrophobicContact CB-CG 3.53Å; Q6-K300 WeakPolarHBondContact O-CE 3.42Å; Y7-K300 WeakPolarHBondContact O-CG 3.45Å; Y7-K300 PolarHBondContact O-N 3.44Å
301	T	77.6	Confident	85.5	Confident	85 Å²	85	45.2 Å²	45.2	52%	0.521	24%	0.238	S	C	.	.			trans	-122.3	126.4	-178.2	50.3	0	0	0	0	109.4	M299	M299-T301 PolarHBondContact O-N 3.06Å
302	K	79.1	Confident	85.9	Confident	12 Å²	12	43.9 Å²	43.9	5%	0.052	23%	0.228	C	C	.	.			trans	-108.5	2.6	-179.9	-53.6	-174	-175	68.2	0	112.3	D121 M122 I296 M299 N304 I305 Y505	D121-K302 VanDerWaalsContact OD1-CD 3.23Å; D121-K302 WeakPolarHBondContact OD1-CD 3.47Å; D121-K302 VanDerWaalsContact OD1-CE 3.22Å; D121-K302 WeakPolarHBondContact OD1-CE 3.23Å; D121-K302 IonicContact OD1-NZ 3.31Å; D121-K302 PolarHBondContact OD1-NZ 3.41Å; D121-K302 IonicContact OD2-NZ 3.54Å; M122-K302 HydrophobicContact CE-CD 3.91Å; I296-K302 HydrophobicContact CG2-CD 4.33Å; I296-K302 WeakPolarHBondContact O-CE 3.31Å; M299-K302 PolarHBondContact O-NZ 3Å; M299-K302 VanDerWaalsContact O-NZ 3.1Å; K302-N304 PolarHBondContact O-N 3.36Å; K302-I305 WeakPolarHBondContact O-CB 3.49Å; K302-I305 PolarHBondContact O-N 3.21Å; K302-Y505 HydrophobicContact CB-CE1 4.25Å
303	R	78.2	Confident	86.4	Confident	195 Å²	195	44 Å²	44	74%	0.736	23%	0.228	S	C	*	.	T	Hydrogen-bonded Turn	trans	-59.6	131.3	172.2	-165.4	172.9	74.3	168.1	2.6	109.9	I305	R303-I305 VanDerWaalsContact C-N 3.31Å; R303-I305 PolarHBondContact O-N 2.86Å
304	N	85.5	Confident	87.3	Confident	100 Å²	100	47.2 Å²	47.2	54%	0.535	25%	0.25	S	S	.	.	T	Hydrogen-bonded Turn	trans	64.4	25.9	-178.5	-54.7	-21.3	0	0	0	115.2	K302 Y306 H307 L308	K302-N304 PolarHBondContact O-N 3.36Å; N304-Y306 VanDerWaalsContact C-N 3.29Å; N304-Y306 PolarHBondContact O-N 2.92Å; N304-H307 HydrophobicContact CB-CB 4.36Å; N304-H307 PolarHBondContact O-N 3.29Å; N304-H307 VanDerWaalsContact O-N 3.12Å; N304-L308 WeakPolarHBondContact O-CG 3.45Å; N304-L308 PolarHBondContact O-N 3.1Å
305	I	89.8	Confident	88.1	Confident	2 Å²	2	50.4 Å²	50.4	1%	0.01	26%	0.256	C	S	.	.	H	α-helix	trans	-54.7	-42.4	-179.1	-167.1	160.7	0	0	0	113.1	V59 I296 K302 R303 H307 L308 V309	V59-I305 HydrophobicContact CG1-CD1 4.37Å; V59-I305 HydrophobicContact CG1-CG2 4.17Å; I296-I305 HydrophobicContact CB-CD1 4.25Å; I296-I305 HydrophobicContact CD1-CD1 3.63Å; I296-I305 HydrophobicContact CG1-CD1 3.87Å; I296-I305 HydrophobicContact CG2-CD1 3.43Å; I296-I305 VanDerWaalsContact CG2-CD1 3.43Å; K302-I305 WeakPolarHBondContact O-CB 3.49Å; K302-I305 PolarHBondContact O-N 3.21Å; R303-I305 VanDerWaalsContact C-N 3.31Å; R303-I305 PolarHBondContact O-N 2.86Å; I305-H307 PolarHBondContact O-N 3.33Å; I305-L308 PolarHBondContact O-N 3.39Å; I305-V309 HydrophobicContact CG1-CG2 4.24Å; I305-V309 WeakPolarHBondContact O-CB 3.42Å; I305-V309 WeakPolarHBondContact O-CG2 3.46Å; I305-V309 PolarHBondContact O-N 3.48Å
306	Y	92.2	Very high	88.7	Confident	24 Å²	24	50 Å²	50	9%	0.094	25%	0.254	C	S	.	.	H	α-helix	trans	-64.1	-39.9	178.8	-60.4	-58.7	0	0	0	112.8	T56 V59 N304 A310 H504 Y505 V506 S507	T56-Y306 HydrophobicContact CG2-CD1 3.66Å; T56-Y306 HydrophobicContact CG2-CE1 4.03Å; V59-Y306 HydrophobicContact CB-CE1 3.86Å; V59-Y306 HydrophobicContact CG1-CE1 4.02Å; V59-Y306 HydrophobicContact CG2-CE1 4.32Å; N304-Y306 VanDerWaalsContact C-N 3.29Å; N304-Y306 PolarHBondContact O-N 2.92Å; Y306-A310 VanDerWaalsContact O-CB 3.31Å; Y306-A310 WeakPolarHBondContact O-CB 3.19Å; Y306-A310 PolarHBondContact O-N 3.46Å; Y306-H504 VanDerWaalsContact CE2-O 3.28Å; Y306-H504 WeakPolarHBondContact CE2-O 3.42Å; Y306-Y505 VanDerWaalsContact OH-C 3.26Å; Y306-Y505 PolarHBondContact OH-O 3.08Å; Y306-V506 WeakPolarHBondContact CE2-O 3.32Å; Y306-S507 PolarHBondContact OH-N 3.18Å
307	H	92.8	Very high	89.3	Confident	128 Å²	128	51 Å²	51	59%	0.593	26%	0.26	S	S	*	.	H	α-helix	trans	-66.2	-46.2	176.4	178	-78.1	0	0	0	110.9	N304 I305 V309 A310 V311	N304-H307 HydrophobicContact CB-CB 4.36Å; N304-H307 PolarHBondContact O-N 3.29Å; N304-H307 VanDerWaalsContact O-N 3.12Å; I305-H307 PolarHBondContact O-N 3.33Å; H307-V309 VanDerWaalsContact C-N 3.3Å; H307-V309 PolarHBondContact O-N 2.86Å; H307-A310 WeakPolarHBondContact O-CB 3.36Å; H307-A310 PolarHBondContact O-N 3.39Å; H307-V311 WeakPolarHBondContact O-CG2 3.31Å; H307-V311 PolarHBondContact O-N 3.44Å
308	L	92.8	Very high	90.1	Very high	54 Å²	54	55.9 Å²	55.9	28%	0.283	29%	0.285	S	S	.	.	H	α-helix	trans	-60.1	-42.7	178.2	-71	175.5	0	0	0	111.7	A9 M13 N304 I305 V311 V312	A9-L308 HydrophobicContact CB-CD1 3.82Å; M13-L308 HydrophobicContact CG-CB 3.85Å; M13-L308 HydrophobicContact CG-CD1 4.47Å; M13-L308 HydrophobicContact SD-CB 3.68Å; N304-L308 WeakPolarHBondContact O-CG 3.45Å; N304-L308 PolarHBondContact O-N 3.1Å; I305-L308 PolarHBondContact O-N 3.39Å; L308-V311 WeakPolarHBondContact O-CB 3.49Å; L308-V311 PolarHBondContact O-N 3.06Å; L308-V312 WeakPolarHBondContact O-CG2 3.12Å; L308-V312 PolarHBondContact O-N 2.63Å; L308-V312 VanDerWaalsContact O-N 3.1Å
309	V	93.4	Very high	90.9	Very high	0 Å²	0	57.1 Å²	57.1	0%	0	29%	0.29	C	S	.	.	H	α-helix	trans	-68.8	-39.5	177.6	176.4	0	0	0	0	111.3	M13 L16 F52 M55 I305 H307 V311 V312 Y313	M13-V309 HydrophobicContact CE-CG2 4Å; M13-V309 HydrophobicContact SD-CG2 3.82Å; L16-V309 HydrophobicContact CD2-CB 4.36Å; L16-V309 HydrophobicContact CD2-CG1 3.88Å; L16-V309 HydrophobicContact CD2-CG2 3.9Å; F52-V309 HydrophobicContact CD2-CG1 4.05Å; F52-V309 HydrophobicContact CE2-CB 4.35Å; F52-V309 HydrophobicContact CE2-CG1 4.15Å; M55-V309 HydrophobicContact CE-CB 3.98Å; M55-V309 HydrophobicContact CE-CG1 3.68Å; M55-V309 HydrophobicContact CE-CG2 3.37Å; M55-V309 HydrophobicContact CG-CG1 4.21Å; M55-V309 HydrophobicContact SD-CB 4.21Å; M55-V309 HydrophobicContact SD-CG1 3.59Å; M55-V309 VanDerWaalsContact SD-CG1 3.59Å; M55-V309 HydrophobicContact SD-CG2 4.24Å; I305-V309 HydrophobicContact CG1-CG2 4.24Å; I305-V309 WeakPolarHBondContact O-CB 3.42Å; I305-V309 WeakPolarHBondContact O-CG2 3.46Å; I305-V309 PolarHBondContact O-N 3.48Å; H307-V309 VanDerWaalsContact C-N 3.3Å; H307-V309 PolarHBondContact O-N 2.86Å; V309-V311 VanDerWaalsContact C-N 3.28Å; V309-V311 PolarHBondContact O-N 2.85Å; V309-V312 WeakPolarHBondContact O-CB 3.2Å; V309-V312 PolarHBondContact O-N 3Å; V309-V312 VanDerWaalsContact O-N 3.08Å; V309-Y313 HydrophobicContact CG1-CD2 3.61Å; V309-Y313 HydrophobicContact CG1-CE2 3.72Å; V309-Y313 WeakPolarHBondContact O-CD2 3.47Å; V309-Y313 PolarHBondContact O-N 3.33Å
310	A	95.3	Very high	91.5	Very high	28 Å²	28	57 Å²	57	23%	0.231	29%	0.289	C	S	.	.	H	α-helix	trans	-57.8	-42.6	174.4	0	0	0	0	0	111.4	F52 Y306 H307 V312 Y313 C314	F52-A310 HydrophobicContact CD2-CB 4.45Å; F52-A310 HydrophobicContact CE1-CB 4.4Å; F52-A310 HydrophobicContact CE2-CB 3.73Å; F52-A310 HydrophobicContact CZ-CB 3.7Å; Y306-A310 VanDerWaalsContact O-CB 3.31Å; Y306-A310 WeakPolarHBondContact O-CB 3.19Å; Y306-A310 PolarHBondContact O-N 3.46Å; H307-A310 WeakPolarHBondContact O-CB 3.36Å; H307-A310 PolarHBondContact O-N 3.39Å; A310-V312 VanDerWaalsContact C-N 3.35Å; A310-V312 PolarHBondContact O-N 2.93Å; A310-Y313 PolarHBondContact O-N 3.45Å; A310-C314 WeakPolarHBondContact O-CB 3.45Å; A310-C314 PolarHBondContact O-N 3.18Å; A310-C314 PolarHBondContact O-SG 3.28Å
311	V	96	Very high	92.4	Very high	64 Å²	64	52.2 Å²	52.2	39%	0.388	27%	0.269	S	S	.	.	H	α-helix	trans	-59.5	-45	173.9	172.3	0	0	0	0	111.1	H307 L308 V309 C314 L315	H307-V311 WeakPolarHBondContact O-CG2 3.31Å; H307-V311 PolarHBondContact O-N 3.44Å; L308-V311 WeakPolarHBondContact O-CB 3.49Å; L308-V311 PolarHBondContact O-N 3.06Å; V309-V311 VanDerWaalsContact C-N 3.28Å; V309-V311 PolarHBondContact O-N 2.85Å; V311-C314 PolarHBondContact O-N 2.98Å; V311-L315 HydrophobicContact CG1-CD1 3.96Å; V311-L315 HydrophobicContact CG1-CG 4.36Å; V311-L315 VanDerWaalsContact O-CG 3.3Å; V311-L315 WeakPolarHBondContact O-CG 3.49Å; V311-L315 PolarHBondContact O-N 2.82Å
312	V	95.4	Very high	93.3	Very high	13 Å²	13	50 Å²	50	8%	0.079	26%	0.259	C	S	.	.	H	α-helix	trans	-60.1	-47.4	176.6	174.7	0	0	0	0	111.3	M13 L16 L20 L308 V309 A310 C314 L315 V316	M13-V312 HydrophobicContact CB-CG2 3.74Å; M13-V312 HydrophobicContact CG-CG2 4.13Å; M13-V312 HydrophobicContact SD-CG2 3.87Å; L16-V312 HydrophobicContact CD2-CB 4.47Å; L16-V312 HydrophobicContact CD2-CG1 4.26Å; L16-V312 HydrophobicContact CG-CG1 4.15Å; L20-V312 HydrophobicContact CD1-CG1 3.98Å; L308-V312 WeakPolarHBondContact O-CG2 3.12Å; L308-V312 PolarHBondContact O-N 2.63Å; L308-V312 VanDerWaalsContact O-N 3.1Å; V309-V312 WeakPolarHBondContact O-CB 3.2Å; V309-V312 PolarHBondContact O-N 3Å; V309-V312 VanDerWaalsContact O-N 3.08Å; A310-V312 VanDerWaalsContact C-N 3.35Å; A310-V312 PolarHBondContact O-N 2.93Å; V312-C314 PolarHBondContact O-N 3.36Å; V312-L315 PolarHBondContact O-N 3.4Å; V312-V316 HydrophobicContact CG1-CG2 4.28Å; V312-V316 WeakPolarHBondContact O-CB 3.27Å; V312-V316 VanDerWaalsContact O-CG2 3.31Å; V312-V316 WeakPolarHBondContact O-CG2 3.46Å; V312-V316 PolarHBondContact O-N 3.06Å
313	Y	96.5	Very high	94.1	Very high	4 Å²	4	49.4 Å²	49.4	2%	0.016	26%	0.257	C	S	.	.	H	α-helix	trans	-61.6	-41.3	177.7	-92.2	-92.1	0	0	0	112.6	L20 S51 F52 M55 F286 C288 V309 A310 V316 L317	L20-Y313 HydrophobicContact CD1-CE2 4.38Å; S51-Y313 VanDerWaalsContact OG-CE1 3.28Å; S51-Y313 WeakPolarHBondContact OG-CE1 3.45Å; S51-Y313 PolarHBondContact OG-OH 3.11Å; F52-Y313 HydrophobicContact CB-CD1 4.04Å; F52-Y313 HydrophobicContact CB-CD2 4.18Å; F52-Y313 HydrophobicContact CB-CE1 4.28Å; F52-Y313 HydrophobicContact CB-CE2 4.39Å; F52-Y313 HydrophobicContact CB-CG 3.97Å; F52-Y313 HydrophobicContact CD2-CD2 4.01Å; F52-Y313 HydrophobicContact CD2-CE2 4.43Å; F52-Y313 HydrophobicContact CD2-CG 4.41Å; M55-Y313 HydrophobicContact CB-CE2 4.42Å; M55-Y313 HydrophobicContact CG-CE2 4.42Å; F286-Y313 AromaticContact CD1-CD1 3.86Å; F286-Y313 HydrophobicContact CD1-CD1 3.86Å; F286-Y313 AromaticContact CD1-CE1 3.76Å; F286-Y313 HydrophobicContact CD1-CE1 3.76Å; F286-Y313 HydrophobicContact CE1-CD1 4.08Å; F286-Y313 HydrophobicContact CE1-CE1 4.44Å; C288-Y313 PolarHBondContact SG-OH 3.4Å; V309-Y313 HydrophobicContact CG1-CD2 3.61Å; V309-Y313 HydrophobicContact CG1-CE2 3.72Å; V309-Y313 WeakPolarHBondContact O-CD2 3.47Å; V309-Y313 PolarHBondContact O-N 3.33Å; A310-Y313 PolarHBondContact O-N 3.45Å; Y313-V316 PolarHBondContact O-N 2.67Å; Y313-L317 VanDerWaalsContact O-CB 3.26Å; Y313-L317 WeakPolarHBondContact O-CB 3.1Å; Y313-L317 PolarHBondContact O-N 3.1Å
314	C	97.4	Very high	95	Very high	75 Å²	75	40.1 Å²	40.1	51%	0.507	22%	0.222	S	C	.	.	H	α-helix	trans	-62.4	-45	174.8	-71.9	0	0	0	0	111.8	A310 V311 V312 L317 L318	A310-C314 WeakPolarHBondContact O-CB 3.45Å; A310-C314 PolarHBondContact O-N 3.18Å; A310-C314 PolarHBondContact O-SG 3.28Å; V311-C314 PolarHBondContact O-N 2.98Å; V312-C314 PolarHBondContact O-N 3.36Å; C314-L317 PolarHBondContact O-N 2.85Å; C314-L318 VanDerWaalsContact O-CG 3.3Å; C314-L318 WeakPolarHBondContact O-CG 3.29Å; C314-L318 PolarHBondContact O-N 2.83Å
315	L	96.4	Very high	95.4	Very high	111 Å²	111	37.4 Å²	37.4	58%	0.581	21%	0.207	S	C	*	.	H	α-helix	trans	-63.9	-43.2	177.9	-70.5	173.6	0	0	0	111.9	V311 V312 L318 F319	V311-L315 HydrophobicContact CG1-CD1 3.96Å; V311-L315 HydrophobicContact CG1-CG 4.36Å; V311-L315 VanDerWaalsContact O-CG 3.3Å; V311-L315 WeakPolarHBondContact O-CG 3.49Å; V311-L315 PolarHBondContact O-N 2.82Å; V312-L315 PolarHBondContact O-N 3.4Å; L315-L318 PolarHBondContact O-N 2.85Å; L315-F319 WeakPolarHBondContact O-CB 3.42Å; L315-F319 PolarHBondContact O-N 3.16Å
316	V	96.6	Very high	95.6	Very high	6 Å²	6	37.9 Å²	37.9	4%	0.036	21%	0.21	C	C	.	.	H	α-helix	trans	-66.1	-41.6	176.9	173.1	0	0	0	0	111.2	L20 V21 F286 V312 Y313 F319 Y320	L20-V316 HydrophobicContact CB-CG1 4.19Å; L20-V316 HydrophobicContact CB-CG2 4.14Å; L20-V316 HydrophobicContact CD1-CG2 4.08Å; V21-V316 HydrophobicContact CG2-CG1 4.37Å; V21-V316 HydrophobicContact CG2-CG2 4.04Å; F286-V316 HydrophobicContact CD1-CG1 4.34Å; F286-V316 HydrophobicContact CE1-CB 4.32Å; F286-V316 HydrophobicContact CE1-CG1 3.72Å; F286-V316 HydrophobicContact CZ-CG1 4.39Å; V312-V316 HydrophobicContact CG1-CG2 4.28Å; V312-V316 WeakPolarHBondContact O-CB 3.27Å; V312-V316 VanDerWaalsContact O-CG2 3.31Å; V312-V316 WeakPolarHBondContact O-CG2 3.46Å; V312-V316 PolarHBondContact O-N 3.06Å; Y313-V316 PolarHBondContact O-N 2.67Å; V316-F319 WeakPolarHBondContact O-CB 3.4Å; V316-F319 PolarHBondContact O-N 3.03Å; V316-Y320 HydrophobicContact CG1-CD1 4.39Å; V316-Y320 HydrophobicContact CG1-CD2 3.85Å; V316-Y320 HydrophobicContact CG1-CE1 4.04Å; V316-Y320 HydrophobicContact CG1-CE2 3.47Å; V316-Y320 VanDerWaalsContact CG1-CE2 3.47Å; V316-Y320 HydrophobicContact CG1-CG 4.31Å; V316-Y320 WeakPolarHBondContact O-CB 3.36Å; V316-Y320 PolarHBondContact O-N 3.25Å
317	L	97.6	Very high	95.5	Very high	25 Å²	25	36.7 Å²	36.7	13%	0.131	21%	0.206	C	C	.	.	H	α-helix	trans	-60.4	-47.6	175.1	174.9	62.9	0	0	0	111.6	L44 T45 F286 Y313 C314 F319 Y320 L321	L44-L317 HydrophobicContact CD2-CD1 4.01Å; L44-L317 HydrophobicContact CG-CD1 3.93Å; T45-L317 HydrophobicContact CG2-CD2 4.22Å; F286-L317 HydrophobicContact CZ-CB 4.19Å; F286-L317 HydrophobicContact CZ-CD1 4.21Å; Y313-L317 VanDerWaalsContact O-CB 3.26Å; Y313-L317 WeakPolarHBondContact O-CB 3.1Å; Y313-L317 PolarHBondContact O-N 3.1Å; C314-L317 PolarHBondContact O-N 2.85Å; L317-F319 VanDerWaalsContact C-N 3.28Å; L317-F319 PolarHBondContact O-N 3.31Å; L317-Y320 PolarHBondContact O-N 3.04Å; L317-L321 HydrophobicContact CD1-CD1 4.01Å; L317-L321 HydrophobicContact CD1-CG 4.06Å; L317-L321 HydrophobicContact CG-CD1 3.99Å; L317-L321 HydrophobicContact CG-CG 4.45Å; L317-L321 WeakPolarHBondContact O-CB 3.4Å; L317-L321 VanDerWaalsContact O-CG 3.3Å; L317-L321 WeakPolarHBondContact O-CG 3.13Å; L317-L321 PolarHBondContact O-N 3.48Å
318	L	97.4	Very high	95.5	Very high	112 Å²	112	31.3 Å²	31.3	59%	0.586	18%	0.182	S	C	*	.	H	α-helix	trans	-60.5	-40.5	176.5	-71	173.3	0	0	0	111.5	C314 L315 A322	C314-L318 VanDerWaalsContact O-CG 3.3Å; C314-L318 WeakPolarHBondContact O-CG 3.29Å; C314-L318 PolarHBondContact O-N 2.83Å; L315-L318 PolarHBondContact O-N 2.85Å; L318-A322 VanDerWaalsContact O-CB 3.3Å; L318-A322 WeakPolarHBondContact O-CB 3.45Å; L318-A322 PolarHBondContact O-N 3.38Å
319	F	96.5	Very high	95.4	Very high	31 Å²	31	31.4 Å²	31.4	14%	0.136	18%	0.181	C	C	.	.	H	α-helix	trans	-63.6	-45.7	175.5	170.6	-104.2	0	0	0	112.4	V21 A25 W244 F247 L315 V316 L317 A322 I323	V21-F319 HydrophobicContact CG1-CD1 4.29Å; V21-F319 HydrophobicContact CG1-CE1 3.67Å; V21-F319 HydrophobicContact CG1-CZ 4.28Å; V21-F319 HydrophobicContact CG2-CD1 4.06Å; V21-F319 HydrophobicContact CG2-CE1 4.27Å; A25-F319 HydrophobicContact CB-CE1 4.32Å; W244-F319 HydrophobicContact CZ3-CD2 4.5Å; F247-F319 HydrophobicContact CB-CE2 3.84Å; F247-F319 HydrophobicContact CB-CZ 3.69Å; F247-F319 AromaticContact CD1-CZ 3.7Å; F247-F319 HydrophobicContact CD1-CZ 3.7Å; F247-F319 HydrophobicContact CD2-CE1 4.46Å; F247-F319 AromaticContact CD2-CZ 3.82Å; F247-F319 HydrophobicContact CD2-CZ 3.82Å; F247-F319 HydrophobicContact CE1-CZ 4.28Å; F247-F319 HydrophobicContact CE2-CZ 4.36Å; F247-F319 HydrophobicContact CG-CE1 4.47Å; F247-F319 HydrophobicContact CG-CE2 4.18Å; F247-F319 AromaticContact CG-CZ 3.49Å; F247-F319 HydrophobicContact CG-CZ 3.49Å; F247-F319 VanDerWaalsContact CG-CZ 3.49Å; L315-F319 WeakPolarHBondContact O-CB 3.42Å; L315-F319 PolarHBondContact O-N 3.16Å; V316-F319 WeakPolarHBondContact O-CB 3.4Å; V316-F319 PolarHBondContact O-N 3.03Å; L317-F319 VanDerWaalsContact C-N 3.28Å; L317-F319 PolarHBondContact O-N 3.31Å; F319-A322 PolarHBondContact O-N 3.18Å; F319-I323 HydrophobicContact CZ-CD1 4.38Å; F319-I323 PolarHBondContact O-N 3.21Å
320	Y	97.5	Very high	95.1	Very high	0 Å²	0	31.9 Å²	31.9	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-66.1	-38.7	176.8	-71.9	-11.1	0	0	0	112.9	L20 V21 A25 L28 S285 F286 V316 L317 I323 S324	L20-Y320 VanDerWaalsContact C-OH 3.32Å; L20-Y320 PolarHBondContact O-OH 2.97Å; V21-Y320 HydrophobicContact CG2-CE1 4.46Å; A25-Y320 HydrophobicContact CB-CD1 4.17Å; A25-Y320 HydrophobicContact CB-CE1 3.64Å; L28-Y320 HydrophobicContact CD1-CD1 3.89Å; L28-Y320 HydrophobicContact CD1-CD2 3.71Å; L28-Y320 HydrophobicContact CD1-CE1 4.37Å; L28-Y320 HydrophobicContact CD1-CE2 4.2Å; L28-Y320 HydrophobicContact CD1-CG 3.54Å; S285-Y320 WeakPolarHBondContact O-CE2 3.34Å; S285-Y320 PolarHBondContact O-OH 3.21Å; F286-Y320 HydrophobicContact CD1-CE2 4.32Å; F286-Y320 HydrophobicContact CD2-CD2 4.42Å; F286-Y320 HydrophobicContact CD2-CE2 4.36Å; F286-Y320 HydrophobicContact CE1-CD2 4.1Å; F286-Y320 HydrophobicContact CE1-CE2 4.06Å; F286-Y320 AromaticContact CE2-CD2 3.76Å; F286-Y320 HydrophobicContact CE2-CD2 3.76Å; F286-Y320 HydrophobicContact CE2-CE2 4.11Å; F286-Y320 HydrophobicContact CG-CE2 4.46Å; F286-Y320 AromaticContact CZ-CD2 3.56Å; F286-Y320 HydrophobicContact CZ-CD2 3.56Å; F286-Y320 AromaticContact CZ-CE2 3.94Å; F286-Y320 HydrophobicContact CZ-CE2 3.94Å; V316-Y320 HydrophobicContact CG1-CD1 4.39Å; V316-Y320 HydrophobicContact CG1-CD2 3.85Å; V316-Y320 HydrophobicContact CG1-CE1 4.04Å; V316-Y320 HydrophobicContact CG1-CE2 3.47Å; V316-Y320 VanDerWaalsContact CG1-CE2 3.47Å; V316-Y320 HydrophobicContact CG1-CG 4.31Å; V316-Y320 WeakPolarHBondContact O-CB 3.36Å; V316-Y320 PolarHBondContact O-N 3.25Å; L317-Y320 PolarHBondContact O-N 3.04Å; Y320-I323 WeakPolarHBondContact O-CG2 3.49Å; Y320-S324 VanDerWaalsContact O-CB 3.29Å; Y320-S324 WeakPolarHBondContact O-CB 3.37Å; Y320-S324 PolarHBondContact O-N 2.95Å; Y320-S324 PolarHBondContact O-OG 3.03Å
321	L	97.3	Very high	94.7	Very high	27 Å²	27	30.8 Å²	30.8	14%	0.141	18%	0.176	C	C	.	.	H	α-helix	trans	-64.2	-42.7	172	-70.8	172.2	0	0	0	111	F32 I41 L44 L317 L325	F32-L321 HydrophobicContact CE1-CD2 4.34Å; F32-L321 HydrophobicContact CZ-CD2 4.25Å; I41-L321 HydrophobicContact CB-CD2 4.32Å; I41-L321 HydrophobicContact CG1-CD2 3.96Å; I41-L321 HydrophobicContact CG2-CD2 4.34Å; L44-L321 HydrophobicContact CD2-CD2 3.86Å; L44-L321 HydrophobicContact CD2-CG 4.11Å; L317-L321 HydrophobicContact CD1-CD1 4.01Å; L317-L321 HydrophobicContact CD1-CG 4.06Å; L317-L321 HydrophobicContact CG-CD1 3.99Å; L317-L321 HydrophobicContact CG-CG 4.45Å; L317-L321 WeakPolarHBondContact O-CB 3.4Å; L317-L321 VanDerWaalsContact O-CG 3.3Å; L317-L321 WeakPolarHBondContact O-CG 3.13Å; L317-L321 PolarHBondContact O-N 3.48Å; L321-L325 HydrophobicContact CB-CD1 4.44Å; L321-L325 WeakPolarHBondContact O-CB 3.47Å; L321-L325 WeakPolarHBondContact O-CG 3.13Å; L321-L325 PolarHBondContact O-N 3.04Å
322	A	96.2	Very high	94.1	Very high	38 Å²	38	37.3 Å²	37.3	31%	0.314	19%	0.193	S	C	.	.	H	α-helix	trans	-61.3	-49.9	178.1	0	0	0	0	0	111.6	L318 F319 T326	L318-A322 VanDerWaalsContact O-CB 3.3Å; L318-A322 WeakPolarHBondContact O-CB 3.45Å; L318-A322 PolarHBondContact O-N 3.38Å; F319-A322 PolarHBondContact O-N 3.18Å; A322-T326 VanDerWaalsContact O-CB 3.25Å; A322-T326 WeakPolarHBondContact O-CB 3.07Å; A322-T326 WeakPolarHBondContact O-CG2 3.17Å; A322-T326 PolarHBondContact O-N 3.42Å; A322-T326 PolarHBondContact O-OG1 2.95Å
323	I	95.6	Very high	93.6	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-65.7	-42.6	-179.4	-161	175.9	0	0	0	112	P29 F247 V251 F319 Y320 T326 G327 Y338	P29-I323 HydrophobicContact CG-CG1 4.32Å; F247-I323 HydrophobicContact CD1-CD1 3.48Å; F247-I323 VanDerWaalsContact CD1-CD1 3.48Å; F247-I323 HydrophobicContact CE1-CD1 3.61Å; V251-I323 HydrophobicContact CG2-CB 4.13Å; V251-I323 HydrophobicContact CG2-CG1 4.2Å; F319-I323 HydrophobicContact CZ-CD1 4.38Å; F319-I323 PolarHBondContact O-N 3.21Å; Y320-I323 WeakPolarHBondContact O-CG2 3.49Å; I323-T326 PolarHBondContact O-OG1 2.68Å; I323-G327 PolarHBondContact O-N 2.83Å; I323-Y338 HydrophobicContact CD1-CD1 3.84Å; I323-Y338 HydrophobicContact CD1-CE1 3.97Å; I323-Y338 HydrophobicContact CG1-CD1 3.83Å; I323-Y338 HydrophobicContact CG1-CE1 3.49Å; I323-Y338 VanDerWaalsContact CG1-CE1 3.49Å
324	S	95.8	Very high	93.3	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-69.3	-47.9	-179.3	-62.6	0	0	0	0	112.6	L28 Y320 G327 V328	L28-S324 WeakPolarHBondContact CB-OG 3.44Å; Y320-S324 VanDerWaalsContact O-CB 3.29Å; Y320-S324 WeakPolarHBondContact O-CB 3.37Å; Y320-S324 PolarHBondContact O-N 2.95Å; Y320-S324 PolarHBondContact O-OG 3.03Å; S324-G327 PolarHBondContact O-N 3Å; S324-V328 WeakPolarHBondContact O-CG2 3.27Å; S324-V328 PolarHBondContact O-N 3.01Å
325	L	94.4	Very high	93	Very high	43 Å²	43	36.2 Å²	36.2	23%	0.225	18%	0.18	C	C	.	.	H	α-helix	trans	-66.6	-45.2	-179.4	-64.9	173.6	0	0	0	110.5	F32 I41 L321 G327 V328 M329	F32-L325 HydrophobicContact CD1-CD2 4.4Å; F32-L325 HydrophobicContact CE1-CD2 4.4Å; I41-L325 HydrophobicContact CD1-CD1 4.33Å; I41-L325 HydrophobicContact CD1-CD2 3.98Å; I41-L325 HydrophobicContact CG1-CD1 4.43Å; I41-L325 HydrophobicContact CG1-CD2 4.09Å; L321-L325 HydrophobicContact CB-CD1 4.44Å; L321-L325 WeakPolarHBondContact O-CB 3.47Å; L321-L325 WeakPolarHBondContact O-CG 3.13Å; L321-L325 PolarHBondContact O-N 3.04Å; L325-G327 VanDerWaalsContact C-N 3.28Å; L325-G327 PolarHBondContact O-N 2.72Å; L325-V328 PolarHBondContact O-N 3.48Å; L325-M329 HydrophobicContact CB-CE 4.13Å; L325-M329 VanDerWaalsContact O-CB 3.29Å; L325-M329 WeakPolarHBondContact O-CB 3.38Å; L325-M329 VanDerWaalsContact O-CE 3.31Å; L325-M329 WeakPolarHBondContact O-CE 3.32Å; L325-M329 WeakPolarHBondContact O-CG 3.39Å; L325-M329 PolarHBondContact O-N 2.91Å
326	T	93.6	Very high	92.8	Very high	12 Å²	12	31.4 Å²	31.4	7%	0.074	16%	0.155	C	C	.	.	H	α-helix	trans	-62	-37.8	177.3	57.7	0	0	0	0	111.5	T255 A322 I323 M329 A330	T255-T326 WeakPolarHBondContact OG1-CG2 3.46Å; A322-T326 VanDerWaalsContact O-CB 3.25Å; A322-T326 WeakPolarHBondContact O-CB 3.07Å; A322-T326 WeakPolarHBondContact O-CG2 3.17Å; A322-T326 PolarHBondContact O-N 3.42Å; A322-T326 PolarHBondContact O-OG1 2.95Å; I323-T326 PolarHBondContact O-OG1 2.68Å; T326-M329 HydrophobicContact CG2-CE 4.42Å; T326-A330 WeakPolarHBondContact O-CB 3.08Å; T326-A330 PolarHBondContact O-N 3.34Å
327	G	92	Very high	92.6	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-61.9	-53.9	174.2	0	0	0	0	0	113.4	I323 S324 L325 M329 A330 F331 Y338	I323-G327 PolarHBondContact O-N 2.83Å; S324-G327 PolarHBondContact O-N 3Å; L325-G327 VanDerWaalsContact C-N 3.28Å; L325-G327 PolarHBondContact O-N 2.72Å; G327-M329 PolarHBondContact O-N 3.08Å; G327-A330 PolarHBondContact O-N 3.47Å; G327-A330 VanDerWaalsContact O-N 3.17Å; G327-F331 WeakPolarHBondContact O-CD2 3.27Å; G327-F331 PolarHBondContact O-N 3.01Å; G327-Y338 WeakPolarHBondContact CA-OH 3.41Å; G327-Y338 PolarHBondContact N-OH 3.37Å
328	V	91.8	Very high	92.4	Very high	14 Å²	14	30 Å²	30	9%	0.085	15%	0.147	C	C	.	.	H	α-helix	trans	-62.2	-33.6	-179.9	176	0	0	0	0	112.2	F32 Q33 L267 S324 L325	F32-V328 HydrophobicContact CB-CG2 3.7Å; Q33-V328 HydrophobicContact CB-CG2 4.1Å; L267-V328 HydrophobicContact CD2-CG1 4.1Å; L267-V328 HydrophobicContact CG-CG1 4.3Å; S324-V328 WeakPolarHBondContact O-CG2 3.27Å; S324-V328 PolarHBondContact O-N 3.01Å; L325-V328 PolarHBondContact O-N 3.48Å
329	M	90.3	Very high	92.2	Very high	56 Å²	56	24.7 Å²	24.7	28%	0.276	12%	0.119	S	C	.	.	H	α-helix	trans	-78.4	-27.4	178.4	-65.8	177.4	-41.5	0	0	113.1	A258 W262 L267 L325 T326 G327	A258-M329 HydrophobicContact CB-CB 4Å; W262-M329 HydrophobicContact CE3-CB 4.28Å; W262-M329 HydrophobicContact CH2-CB 4.11Å; W262-M329 HydrophobicContact CH2-CG 3.6Å; W262-M329 HydrophobicContact CH2-SD 3.26Å; W262-M329 WeakPolarHBondContact CH2-SD 3.36Å; W262-M329 HydrophobicContact CZ3-CB 3.56Å; W262-M329 HydrophobicContact CZ3-CE 4.18Å; W262-M329 HydrophobicContact CZ3-CG 3.57Å; W262-M329 HydrophobicContact CZ3-SD 3.36Å; W262-M329 WeakPolarHBondContact CZ3-SD 3.35Å; L267-M329 HydrophobicContact CD2-CG 4.23Å; L325-M329 HydrophobicContact CB-CE 4.13Å; L325-M329 VanDerWaalsContact O-CB 3.29Å; L325-M329 WeakPolarHBondContact O-CB 3.38Å; L325-M329 VanDerWaalsContact O-CE 3.31Å; L325-M329 WeakPolarHBondContact O-CE 3.32Å; L325-M329 WeakPolarHBondContact O-CG 3.39Å; L325-M329 PolarHBondContact O-N 2.91Å; T326-M329 HydrophobicContact CG2-CE 4.42Å; G327-M329 PolarHBondContact O-N 3.08Å
330	A	88.3	Confident	92	Very high	11 Å²	11	23.3 Å²	23.3	9%	0.091	11%	0.113	C	C	.	.	H	α-helix	trans	-90.6	-27.5	-175.8	0	0	0	0	0	113.9	A254 R257 A258 T326 G327	A254-A330 HydrophobicContact CB-CB 3.98Å; A254-A330 WeakPolarHBondContact O-CB 3.05Å; R257-A330 HydrophobicContact CB-CB 4.22Å; R257-A330 WeakPolarHBondContact CD-O 3.12Å; R257-A330 HydrophobicContact CG-CB 4.38Å; R257-A330 PolarHBondContact NE-O 3.24Å; A258-A330 HydrophobicContact CB-CB 4.36Å; T326-A330 WeakPolarHBondContact O-CB 3.08Å; T326-A330 PolarHBondContact O-N 3.34Å; G327-A330 PolarHBondContact O-N 3.47Å; G327-A330 VanDerWaalsContact O-N 3.17Å
331	F	86.5	Confident	91.6	Very high	5 Å²	5	23.3 Å²	23.3	2%	0.022	11%	0.113	C	C	.	.			trans	-125.7	131.7	-170.9	-58.1	-88.1	0	0	0	112.3	Q33 A254 G327 V334 Y338 N341 F342 L345	Q33-F331 PolarHBondContact NE2-O 3.23Å; A254-F331 HydrophobicContact CB-CE2 4.35Å; G327-F331 WeakPolarHBondContact O-CD2 3.27Å; G327-F331 PolarHBondContact O-N 3.01Å; F331-V334 HydrophobicContact CB-CG2 4.01Å; F331-Y338 HydrophobicContact CD2-CE2 4Å; F331-Y338 AromaticContact CE2-CE2 3.73Å; F331-Y338 HydrophobicContact CE2-CE2 3.73Å; F331-N341 HydrophobicContact CD1-CB 3.78Å; F331-N341 HydrophobicContact CD2-CB 4.34Å; F331-N341 HydrophobicContact CE1-CB 3.52Å; F331-N341 WeakPolarHBondContact CE1-O 3.34Å; F331-N341 HydrophobicContact CE2-CB 4.14Å; F331-N341 HydrophobicContact CG-CB 4.2Å; F331-N341 HydrophobicContact CZ-CB 3.74Å; F331-F342 HydrophobicContact CE2-CE1 4.22Å; F331-F342 HydrophobicContact CE2-CE2 4.38Å; F331-F342 AromaticContact CE2-CZ 3.98Å; F331-F342 HydrophobicContact CE2-CZ 3.98Å; F331-F342 HydrophobicContact CZ-CD1 4.03Å; F331-F342 HydrophobicContact CZ-CD2 4.48Å; F331-F342 AromaticContact CZ-CE1 3.8Å; F331-F342 HydrophobicContact CZ-CE1 3.8Å; F331-F342 HydrophobicContact CZ-CE2 4.27Å; F331-F342 HydrophobicContact CZ-CG 4.38Å; F331-F342 AromaticContact CZ-CZ 3.94Å; F331-F342 HydrophobicContact CZ-CZ 3.94Å; F331-L345 HydrophobicContact CE1-CD1 4.01Å; F331-L345 HydrophobicContact CE1-CG 4.39Å; F331-L345 HydrophobicContact CZ-CD1 4.39Å
332	R	82.7	Confident	91.2	Very high	201 Å²	201	22 Å²	22	76%	0.758	11%	0.107	S	C	*	.	S	Bend	trans	-66.7	-36.8	173.9	-179.5	177	176.4	168	-0.2	112.7	Q33 F186	Q33-R332 PolarHBondContact NE2-O 3.33Å; F186-R332 HydrophobicContact CD1-CB 3.65Å; F186-R332 HydrophobicContact CD1-CG 4.39Å; F186-R332 HydrophobicContact CE1-CB 3.74Å; F186-R332 HydrophobicContact CE1-CG 4.34Å
333	H	85.8	Confident	90.6	Very high	46 Å²	46	21.5 Å²	21.5	21%	0.213	10%	0.097	C	C	.	.	S	Bend	trans	-127.3	121.2	172.5	-175.9	60.8	0	0	0	107.4	R30 N189 E335 N341	R30-H333 PolarHBondContact NH1-CE1 3.11Å; R30-H333 PolarHBondContact NH1-ND1 3.44Å; N189-H333 PolarHBondContact ND2-NE2 3.3Å; H333-E335 IonicContact CD2-OE1 2.91Å; H333-N341 PolarHBondContact O-ND2 3.07Å
334	V	90	Very high	89.6	Confident	0 Å²	0	22.7 Å²	22.7	0%	0	10%	0.103	C	C	.	.			trans	-96.2	131.4	174.5	179	0	0	0	0	107.2	P29 R30 Q33 F331 Y338 N341	P29-V334 HydrophobicContact CB-CG1 3.79Å; R30-V334 HydrophobicContact CB-CG1 4.1Å; R30-V334 WeakPolarHBondContact CD-O 3.46Å; R30-V334 PolarHBondContact NH1-O 2.91Å; R30-V334 VanDerWaalsContact NH1-O 3.11Å; Q33-V334 HydrophobicContact CB-CB 4.42Å; Q33-V334 HydrophobicContact CB-CG2 4.37Å; F331-V334 HydrophobicContact CB-CG2 4.01Å; V334-Y338 HydrophobicContact CG1-CD2 4.18Å; V334-N341 WeakPolarHBondContact CA-ND2 3.32Å
335	E	90.8	Very high	88.6	Confident	22 Å²	22	23.9 Å²	23.9	10%	0.103	11%	0.109	C	C	.	.			trans	-78.1	152.1	177.3	-64	-73	169	0	0	109.5	H333 V337 L340 N341 Q344	H333-E335 IonicContact CD2-OE1 2.91Å; E335-V337 PolarHBondContact O-N 3.37Å; E335-V337 VanDerWaalsContact O-N 3.13Å; E335-L340 HydrophobicContact CB-CB 3.97Å; E335-L340 HydrophobicContact CB-CD1 4.37Å; E335-L340 HydrophobicContact CG-CB 3.92Å; E335-N341 WeakPolarHBondContact CB-OD1 3.21Å; E335-N341 PolarHBondContact N-ND2 3.45Å; E335-N341 PolarHBondContact N-OD1 3.07Å; E335-Q344 PolarHBondContact OE1-NE2 3.24Å; E335-Q344 PolarHBondContact OE1-OE1 2.99Å
336	D	91.3	Very high	87.1	Confident	11 Å²	11	26.2 Å²	26.2	6%	0.059	12%	0.119	C	C	.	.	S	Bend	trans	-59	-23.2	176.3	64.9	-14.5	0	0	0	113.4	A27 K165 V463 E464	A27-D336 WeakPolarHBondContact CA-O 3.46Å; K165-D336 WeakPolarHBondContact CE-OD1 3.46Å; K165-D336 VanDerWaalsContact NZ-CG 3.26Å; K165-D336 IonicContact NZ-OD1 3.36Å; K165-D336 PolarHBondContact NZ-OD1 3.46Å; K165-D336 VanDerWaalsContact NZ-OD1 3.12Å; K165-D336 IonicContact NZ-OD2 3.59Å; K165-D336 PolarHBondContact NZ-OD2 3.43Å; D336-V463 HydrophobicContact CB-CB 4.34Å; D336-V463 PolarHBondContact OD2-N 3.45Å; D336-E464 HydrophobicContact CB-CB 4.1Å
337	V	93.4	Very high	85.3	Confident	1 Å²	1	27.7 Å²	27.7	1%	0.006	13%	0.132	C	C	.	.	S	Bend	trans	-115.4	101.5	168.6	-177	0	0	0	0	109.5	V162 K165 E335 V339 L340 V463	V162-V337 HydrophobicContact CG1-CG1 4.18Å; V162-V337 HydrophobicContact CG1-CG2 4.34Å; V162-V337 HydrophobicContact CG2-CG2 4.2Å; K165-V337 HydrophobicContact CD-CG2 4.45Å; E335-V337 PolarHBondContact O-N 3.37Å; E335-V337 VanDerWaalsContact O-N 3.13Å; V337-V339 HydrophobicContact CG1-CG2 3.63Å; V337-V339 PolarHBondContact O-N 2.96Å; V337-L340 HydrophobicContact CB-CD1 3.86Å; V337-L340 HydrophobicContact CB-CG 3.98Å; V337-L340 HydrophobicContact CG1-CG 4.26Å; V337-L340 VanDerWaalsContact O-CB 3.27Å; V337-L340 WeakPolarHBondContact O-CB 3.46Å; V337-L340 VanDerWaalsContact O-CG 3.28Å; V337-L340 WeakPolarHBondContact O-CG 3.39Å; V337-L340 PolarHBondContact O-N 3.25Å; V337-V463 HydrophobicContact CG2-CB 3.95Å; V337-V463 HydrophobicContact CG2-CG1 4.07Å; V337-V463 HydrophobicContact CG2-CG2 3.68Å
338	Y	93.6	Very high	83.5	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	16%	0.162	C	C	.	.	T	Hydrogen-bonded Turn	trans	-54.7	-28.5	-170.1	-175.5	-132	0	0	0	116	L26 P29 M250 A254 I323 G327 F331 V334 L340 N341 F342	L26-Y338 WeakPolarHBondContact O-CB 3.5Å; L26-Y338 PolarHBondContact O-N 3.44Å; P29-Y338 HydrophobicContact CB-CD2 3.92Å; P29-Y338 HydrophobicContact CB-CE2 4.17Å; P29-Y338 HydrophobicContact CB-CG 4.26Å; P29-Y338 HydrophobicContact CG-CD1 4.02Å; P29-Y338 HydrophobicContact CG-CD2 3.97Å; P29-Y338 HydrophobicContact CG-CE1 4.33Å; P29-Y338 HydrophobicContact CG-CE2 4.31Å; P29-Y338 HydrophobicContact CG-CG 3.81Å; M250-Y338 HydrophobicContact CB-CE1 4.08Å; M250-Y338 HydrophobicContact SD-CD1 3.8Å; M250-Y338 HydrophobicContact SD-CE1 4.24Å; A254-Y338 WeakPolarHBondContact CB-OH 3.07Å; I323-Y338 HydrophobicContact CD1-CD1 3.84Å; I323-Y338 HydrophobicContact CD1-CE1 3.97Å; I323-Y338 HydrophobicContact CG1-CD1 3.83Å; I323-Y338 HydrophobicContact CG1-CE1 3.49Å; I323-Y338 VanDerWaalsContact CG1-CE1 3.49Å; G327-Y338 WeakPolarHBondContact CA-OH 3.41Å; G327-Y338 PolarHBondContact N-OH 3.37Å; F331-Y338 HydrophobicContact CD2-CE2 4Å; F331-Y338 AromaticContact CE2-CE2 3.73Å; F331-Y338 HydrophobicContact CE2-CE2 3.73Å; V334-Y338 HydrophobicContact CG1-CD2 4.18Å; Y338-L340 PolarHBondContact O-N 3.5Å; Y338-N341 WeakPolarHBondContact O-CB 3.38Å; Y338-N341 PolarHBondContact O-N 2.87Å; Y338-F342 AromaticContact CD1-CE2 3.94Å; Y338-F342 HydrophobicContact CD1-CE2 3.94Å; Y338-F342 HydrophobicContact CD2-CE2 4.25Å; Y338-F342 AromaticContact CE1-CE2 3.58Å; Y338-F342 HydrophobicContact CE1-CE2 3.58Å; Y338-F342 AromaticContact CE1-CZ 3.84Å; Y338-F342 HydrophobicContact CE1-CZ 3.84Å; Y338-F342 AromaticContact CE2-CE2 3.9Å; Y338-F342 HydrophobicContact CE2-CE2 3.9Å; Y338-F342 HydrophobicContact CE2-CZ 4.21Å; Y338-F342 HydrophobicContact CG-CE2 4.27Å; Y338-F342 AromaticContact CZ-CE2 3.57Å; Y338-F342 AromaticContact CZ-CZ 3.6Å; Y338-F342 WeakPolarHBondContact O-CD2 3.47Å
339	V	93.3	Very high	81.6	Confident	0 Å²	0	39.1 Å²	39.1	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-61.2	-27.5	176.7	-66.9	0	0	0	0	112.8	L26 M250 V337 N341 F342 F343 L363 Y366 P367	L26-V339 HydrophobicContact CD2-CG1 4.02Å; M250-V339 HydrophobicContact CE-CG1 4.01Å; M250-V339 HydrophobicContact SD-CB 4.35Å; M250-V339 HydrophobicContact SD-CG1 3.5Å; M250-V339 VanDerWaalsContact SD-CG1 3.5Å; V337-V339 HydrophobicContact CG1-CG2 3.63Å; V337-V339 PolarHBondContact O-N 2.96Å; V339-N341 VanDerWaalsContact C-N 3.28Å; V339-N341 PolarHBondContact O-N 2.95Å; V339-F342 PolarHBondContact O-N 3.44Å; V339-F343 PolarHBondContact O-N 3.3Å; V339-L363 WeakPolarHBondContact CB-O 3.36Å; V339-L363 WeakPolarHBondContact CG1-O 3.3Å; V339-Y366 HydrophobicContact CG1-CD1 4.13Å; V339-P367 HydrophobicContact CG1-CG 4.39Å; V339-P367 HydrophobicContact CG2-CG 3.72Å
340	L	91.1	Very high	79.9	Confident	2 Å²	2	40.8 Å²	40.8	1%	0.01	20%	0.201	C	C	.	.	H	α-helix	trans	-65.7	-34	-177.5	-60.9	-178.4	0	0	0	111.6	K165 N169 E335 V337 Y338 F342 F343 Q344 V364	K165-L340 HydrophobicContact CD-CD1 4.46Å; K165-L340 HydrophobicContact CG-CD1 4.16Å; N169-L340 HydrophobicContact CB-CD2 3.76Å; E335-L340 HydrophobicContact CB-CB 3.97Å; E335-L340 HydrophobicContact CB-CD1 4.37Å; E335-L340 HydrophobicContact CG-CB 3.92Å; V337-L340 HydrophobicContact CB-CD1 3.86Å; V337-L340 HydrophobicContact CB-CG 3.98Å; V337-L340 HydrophobicContact CG1-CG 4.26Å; V337-L340 VanDerWaalsContact O-CB 3.27Å; V337-L340 WeakPolarHBondContact O-CB 3.46Å; V337-L340 VanDerWaalsContact O-CG 3.28Å; V337-L340 WeakPolarHBondContact O-CG 3.39Å; V337-L340 PolarHBondContact O-N 3.25Å; Y338-L340 PolarHBondContact O-N 3.5Å; L340-F342 PolarHBondContact O-N 3.2Å; L340-F343 PolarHBondContact O-N 3.12Å; L340-F343 VanDerWaalsContact O-N 3.1Å; L340-Q344 WeakPolarHBondContact O-CG 3.38Å; L340-Q344 PolarHBondContact O-N 3.42Å; L340-Q344 VanDerWaalsContact O-N 3.08Å; L340-V364 HydrophobicContact CD2-CG2 4.07Å
341	N	89.3	Confident	78.2	Confident	0 Å²	0	49.3 Å²	49.3	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-58.6	-35.1	178.1	-72.1	105.5	0	0	0	113.1	S187 F331 H333 V334 E335 Y338 V339	S187-N341 PolarHBondContact OG-O 3.02Å; F331-N341 HydrophobicContact CD1-CB 3.78Å; F331-N341 HydrophobicContact CD2-CB 4.34Å; F331-N341 HydrophobicContact CE1-CB 3.52Å; F331-N341 WeakPolarHBondContact CE1-O 3.34Å; F331-N341 HydrophobicContact CE2-CB 4.14Å; F331-N341 HydrophobicContact CG-CB 4.2Å; F331-N341 HydrophobicContact CZ-CB 3.74Å; H333-N341 PolarHBondContact O-ND2 3.07Å; V334-N341 WeakPolarHBondContact CA-ND2 3.32Å; E335-N341 WeakPolarHBondContact CB-OD1 3.21Å; E335-N341 PolarHBondContact N-ND2 3.45Å; E335-N341 PolarHBondContact N-OD1 3.07Å; Y338-N341 WeakPolarHBondContact O-CB 3.38Å; Y338-N341 PolarHBondContact O-N 2.87Å; V339-N341 VanDerWaalsContact C-N 3.28Å; V339-N341 PolarHBondContact O-N 2.95Å
342	F	89	Confident	76.8	Confident	1 Å²	1	54.4 Å²	54.4	0%	0.004	27%	0.266	C	S	.	.	H	α-helix	trans	-79.1	-32.7	177.7	-60.3	-86.3	0	0	0	112.2	M250 W253 A254 F331 Y338 V339 L340 Q344 L345 L363	M250-F342 HydrophobicContact CB-CD2 4.47Å; M250-F342 HydrophobicContact CB-CE1 4.4Å; M250-F342 HydrophobicContact CB-CE2 3.67Å; M250-F342 HydrophobicContact CB-CZ 3.62Å; M250-F342 HydrophobicContact CG-CD2 3.79Å; M250-F342 HydrophobicContact CG-CE2 3.43Å; M250-F342 VanDerWaalsContact CG-CE2 3.43Å; M250-F342 HydrophobicContact CG-CG 4.48Å; M250-F342 HydrophobicContact CG-CZ 3.85Å; M250-F342 WeakPolarHBondContact O-CE1 3.13Å; M250-F342 VanDerWaalsContact O-CZ 3.29Å; M250-F342 WeakPolarHBondContact O-CZ 3.49Å; M250-F342 HydrophobicContact SD-CD2 4.09Å; M250-F342 HydrophobicContact SD-CE2 3.78Å; W253-F342 HydrophobicContact CB-CD1 4.2Å; W253-F342 HydrophobicContact CB-CE1 3.87Å; W253-F342 AromaticContact CD2-CD1 3.65Å; W253-F342 HydrophobicContact CD2-CD1 3.65Å; W253-F342 HydrophobicContact CD2-CE1 4.22Å; W253-F342 HydrophobicContact CE3-CB 4.21Å; W253-F342 AromaticContact CE3-CD1 3.52Å; W253-F342 HydrophobicContact CE3-CD1 3.52Å; W253-F342 HydrophobicContact CE3-CE1 4.35Å; W253-F342 HydrophobicContact CE3-CG 4.25Å; W253-F342 AromaticContact CG-CD1 3.96Å; W253-F342 HydrophobicContact CG-CD1 3.96Å; W253-F342 HydrophobicContact CG-CE1 4.03Å; W253-F342 HydrophobicContact CH2-CB 4.47Å; W253-F342 HydrophobicContact CZ3-CB 3.97Å; W253-F342 HydrophobicContact CZ3-CD1 4.13Å; W253-F342 HydrophobicContact CZ3-CG 4.5Å; A254-F342 HydrophobicContact CB-CE1 4.23Å; A254-F342 HydrophobicContact CB-CZ 4.04Å; F331-F342 HydrophobicContact CE2-CE1 4.22Å; F331-F342 HydrophobicContact CE2-CE2 4.38Å; F331-F342 AromaticContact CE2-CZ 3.98Å; F331-F342 HydrophobicContact CE2-CZ 3.98Å; F331-F342 HydrophobicContact CZ-CD1 4.03Å; F331-F342 HydrophobicContact CZ-CD2 4.48Å; F331-F342 AromaticContact CZ-CE1 3.8Å; F331-F342 HydrophobicContact CZ-CE1 3.8Å; F331-F342 HydrophobicContact CZ-CE2 4.27Å; F331-F342 HydrophobicContact CZ-CG 4.38Å; F331-F342 AromaticContact CZ-CZ 3.94Å; F331-F342 HydrophobicContact CZ-CZ 3.94Å; Y338-F342 AromaticContact CD1-CE2 3.94Å; Y338-F342 HydrophobicContact CD1-CE2 3.94Å; Y338-F342 HydrophobicContact CD2-CE2 4.25Å; Y338-F342 AromaticContact CE1-CE2 3.58Å; Y338-F342 HydrophobicContact CE1-CE2 3.58Å; Y338-F342 AromaticContact CE1-CZ 3.84Å; Y338-F342 HydrophobicContact CE1-CZ 3.84Å; Y338-F342 AromaticContact CE2-CE2 3.9Å; Y338-F342 HydrophobicContact CE2-CE2 3.9Å; Y338-F342 HydrophobicContact CE2-CZ 4.21Å; Y338-F342 HydrophobicContact CG-CE2 4.27Å; Y338-F342 AromaticContact CZ-CE2 3.57Å; Y338-F342 AromaticContact CZ-CZ 3.6Å; Y338-F342 WeakPolarHBondContact O-CD2 3.47Å; V339-F342 PolarHBondContact O-N 3.44Å; L340-F342 PolarHBondContact O-N 3.2Å; F342-Q344 VanDerWaalsContact C-N 3.35Å; F342-L345 PolarHBondContact O-N 3.3Å; F342-L363 HydrophobicContact CB-CD1 3.76Å; F342-L363 HydrophobicContact CD1-CD1 4.46Å; F342-L363 HydrophobicContact CD2-CD1 4.46Å; F342-L363 HydrophobicContact CG-CD1 3.99Å
343	F	84.6	Confident	76.1	Confident	26 Å²	26	48.3 Å²	48.3	11%	0.114	25%	0.248	C	C	.	.	H	α-helix	trans	-67.4	-37.2	177	-173.3	-103.2	0	0	0	111.6	N169 V339 L340 L345 R360 Y361 V364	N169-F343 WeakPolarHBondContact O-CE1 3.28Å; V339-F343 PolarHBondContact O-N 3.3Å; L340-F343 PolarHBondContact O-N 3.12Å; L340-F343 VanDerWaalsContact O-N 3.1Å; F343-L345 VanDerWaalsContact C-N 3.25Å; F343-L345 PolarHBondContact O-N 3.04Å; F343-R360 HydrophobicContact CD2-CB 4.05Å; F343-R360 VanDerWaalsContact O-CZ 3.23Å; F343-R360 PolarHBondContact O-NE 3.41Å; F343-R360 PolarHBondContact O-NH2 3.15Å; F343-Y361 HydrophobicContact CE2-CD1 4.02Å; F343-Y361 HydrophobicContact CE2-CD2 4.45Å; F343-Y361 AromaticContact CE2-CE1 3.87Å; F343-Y361 HydrophobicContact CE2-CE1 3.87Å; F343-Y361 HydrophobicContact CE2-CE2 4.31Å; F343-Y361 HydrophobicContact CE2-CG 4.32Å; F343-Y361 HydrophobicContact CZ-CE1 4.1Å; F343-V364 HydrophobicContact CB-CB 4.09Å; F343-V364 HydrophobicContact CB-CG2 4.19Å; F343-V364 HydrophobicContact CD2-CB 3.82Å; F343-V364 HydrophobicContact CD2-CG1 3.69Å; F343-V364 HydrophobicContact CD2-CG2 4.29Å; F343-V364 HydrophobicContact CE2-CG1 3.96Å; F343-V364 HydrophobicContact CG-CB 4.02Å; F343-V364 HydrophobicContact CG-CG1 4.32Å; F343-V364 HydrophobicContact CG-CG2 4.07Å
344	Q	74.9	Confident	75.8	Confident	25 Å²	25	52.6 Å²	52.6	12%	0.117	27%	0.271	C	S	.	.	T	Hydrogen-bonded Turn	trans	-74.8	-8.1	179.4	-67.3	172.3	-1.4	0	0	114.4	P188 E335 L340 F342 E346	P188-Q344 PolarHBondContact O-OE1 2.87Å; E335-Q344 PolarHBondContact OE1-NE2 3.24Å; E335-Q344 PolarHBondContact OE1-OE1 2.99Å; L340-Q344 WeakPolarHBondContact O-CG 3.38Å; L340-Q344 PolarHBondContact O-N 3.42Å; L340-Q344 VanDerWaalsContact O-N 3.08Å; F342-Q344 VanDerWaalsContact C-N 3.35Å; Q344-E346 PolarHBondContact O-N 3.32Å; Q344-E346 VanDerWaalsContact O-N 3.1Å
345	L	73.7	Confident	75.5	Confident	25 Å²	25	59.6 Å²	59.6	13%	0.131	30%	0.302	C	S	.	.			trans	-72.8	102.3	176.4	-80.3	171.7	0	0	0	110.9	W253 R257 F331 F342 F343 A347 R360	W253-L345 HydrophobicContact CH2-CD1 4.48Å; W253-L345 HydrophobicContact CZ2-CB 4.2Å; W253-L345 HydrophobicContact CZ2-CD1 3.73Å; R257-L345 VanDerWaalsContact CZ-CD2 3.44Å; F331-L345 HydrophobicContact CE1-CD1 4.01Å; F331-L345 HydrophobicContact CE1-CG 4.39Å; F331-L345 HydrophobicContact CZ-CD1 4.39Å; F342-L345 PolarHBondContact O-N 3.3Å; F343-L345 VanDerWaalsContact C-N 3.25Å; F343-L345 PolarHBondContact O-N 3.04Å; L345-A347 PolarHBondContact O-N 3.44Å; L345-R360 PolarHBondContact O-NE 3.1Å; L345-R360 PolarHBondContact O-NH1 2.74Å; L345-R360 PolarHBondContact O-NH2 3Å
346	E	63.7	Low	75.1	Confident	92 Å²	92	59.2 Å²	59.2	43%	0.43	30%	0.304	S	S	.	.			trans	-65	119.3	169.5	-68.9	-168.2	164.5	0	0	110.8	Q344 K348	Q344-E346 PolarHBondContact O-N 3.32Å; Q344-E346 VanDerWaalsContact O-N 3.1Å; E346-K348 PolarHBondContact O-N 2.9Å
347	A	54.9	Low	74.8	Confident	43 Å²	43	60.9 Å²	60.9	36%	0.355	32%	0.316	S	S	.	.			trans	-74.9	104.5	168.5	0	0	0	0	0	107.9	L345 D349 N353	L345-A347 PolarHBondContact O-N 3.44Å; A347-D349 PolarHBondContact O-N 3.48Å; A347-N353 PolarHBondContact O-OD1 2.9Å
348	K	54.1	Low	74.6	Confident	146 Å²	146	65.8 Å²	65.8	64%	0.635	34%	0.341	S	S	*	.			trans	-69.5	-14.3	173.7	-74.3	-167.3	175.4	-162.9	0	113.2	S184 E346 P350	S184-K348 VanDerWaalsContact CB-NZ 3.32Å; E346-K348 PolarHBondContact O-N 2.9Å; K348-P350 WeakPolarHBondContact O-CD 3.37Å
349	D	52.5	Low	74.4	Confident	108 Å²	108	67.4 Å²	67.4	58%	0.578	35%	0.35	S	S	*	.			trans	-88.5	112.4	-176.9	-85.6	-39.3	0	0	0	113.1	A347 H351 L352 N353	A347-D349 PolarHBondContact O-N 3.48Å; D349-H351 PolarHBondContact O-N 2.92Å; D349-H351 VanDerWaalsContact O-N 3.09Å; D349-L352 HydrophobicContact CB-CB 4.46Å; D349-L352 PolarHBondContact O-N 3.43Å; D349-N353 PolarHBondContact O-OD1 3.46Å
350	P	54.1	Low	74.2	Confident	92 Å²	92	69.8 Å²	69.8	60%	0.597	36%	0.359	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.9	-26.5	-177.9	-11.1	18.6	0	0	0	114.1	K348 N353	K348-P350 WeakPolarHBondContact O-CD 3.37Å; P350-N353 WeakPolarHBondContact CA-ND2 3.38Å; P350-N353 WeakPolarHBondContact O-CB 3.45Å
351	H	52.4	Low	74.2	Confident	189 Å²	189	74.6 Å²	74.6	88%	0.875	38%	0.377	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.9	-19.9	-175.4	-69.4	-70.5	0	0	0	114.3	D349	D349-H351 PolarHBondContact O-N 2.92Å; D349-H351 VanDerWaalsContact O-N 3.09Å
352	L	57.1	Low	74.4	Confident	113 Å²	113	77.3 Å²	77.3	59%	0.592	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-1	172	-102	91	0	0	0	113	D349 I354 G356	D349-L352 HydrophobicContact CB-CB 4.46Å; D349-L352 PolarHBondContact O-N 3.43Å; L352-I354 PolarHBondContact O-N 3.27Å; L352-G356 PolarHBondContact O-N 2.93Å
353	N	67.9	Low	74.6	Confident	72 Å²	72	77.2 Å²	77.2	39%	0.385	39%	0.389	S	S	.	.	H	α-helix	trans	-61.6	-41.1	-162.5	-93	-13	0	0	0	114.9	A347 D349 P350 S357	A347-N353 PolarHBondContact O-OD1 2.9Å; D349-N353 PolarHBondContact O-OD1 3.46Å; P350-N353 WeakPolarHBondContact CA-ND2 3.38Å; P350-N353 WeakPolarHBondContact O-CB 3.45Å; N353-S357 WeakPolarHBondContact O-CB 3.44Å; N353-S357 PolarHBondContact O-N 3.47Å
354	I	80.3	Confident	75	Confident	136 Å²	136	76 Å²	76	70%	0.697	38%	0.384	S	S	*	.	H	α-helix	trans	-72	-54.1	-175.8	-58.9	174.3	0	0	0	110.5	L352 G356 S357 I358	L352-I354 PolarHBondContact O-N 3.27Å; I354-G356 PolarHBondContact O-N 3.31Å; I354-S357 PolarHBondContact O-N 2.94Å; I354-I358 HydrophobicContact CG2-CD1 4Å; I354-I358 WeakPolarHBondContact O-CG1 3.3Å; I354-I358 PolarHBondContact O-N 3.46Å
355	F	83.1	Confident	75.8	Confident	147 Å²	147	77 Å²	77	65%	0.645	39%	0.39	S	S	*	.	H	α-helix	trans	-65.2	-41.5	-177.8	-174.7	-106.8	0	0	0	111.8	S357 I358 I359	F355-S357 VanDerWaalsContact C-N 3.34Å; F355-S357 PolarHBondContact O-N 3.45Å; F355-I358 PolarHBondContact O-N 3.34Å; F355-I359 HydrophobicContact CD1-CD1 3.77Å; F355-I359 HydrophobicContact CE1-CD1 3.25Å; F355-I359 HydrophobicContact CE1-CG1 4.26Å; F355-I359 HydrophobicContact CE2-CD1 4.41Å; F355-I359 HydrophobicContact CZ-CD1 3.63Å; F355-I359 HydrophobicContact CZ-CG1 4.31Å; F355-I359 WeakPolarHBondContact O-CG1 3.31Å; F355-I359 PolarHBondContact O-N 2.91Å
356	G	82.9	Confident	76.7	Confident	14 Å²	14	76.1 Å²	76.1	14%	0.144	39%	0.385	C	S	.	.	H	α-helix	trans	-61	-41.4	173.6	0	0	0	0	0	112.5	L352 I354 I359 R360	L352-G356 PolarHBondContact O-N 2.93Å; I354-G356 PolarHBondContact O-N 3.31Å; G356-I359 PolarHBondContact O-N 3.38Å; G356-R360 VanDerWaalsContact O-CG 3.27Å; G356-R360 WeakPolarHBondContact O-CG 3.39Å; G356-R360 PolarHBondContact O-N 3.07Å
357	S	84	Confident	78	Confident	46 Å²	46	71.8 Å²	71.8	32%	0.322	36%	0.364	S	S	.	.	H	α-helix	trans	-63.5	-44.8	175.1	-174.6	0	0	0	0	111.9	N353 I354 F355 I359 R360 Y361	N353-S357 WeakPolarHBondContact O-CB 3.44Å; N353-S357 PolarHBondContact O-N 3.47Å; I354-S357 PolarHBondContact O-N 2.94Å; F355-S357 VanDerWaalsContact C-N 3.34Å; F355-S357 PolarHBondContact O-N 3.45Å; S357-I359 VanDerWaalsContact C-N 3.31Å; S357-I359 PolarHBondContact O-N 3.3Å; S357-R360 PolarHBondContact O-N 3.49Å; S357-Y361 WeakPolarHBondContact O-CD2 3.48Å; S357-Y361 PolarHBondContact O-N 3.04Å
358	I	89.3	Confident	79.7	Confident	105 Å²	105	71 Å²	71	54%	0.538	36%	0.355	S	S	.	.	H	α-helix	trans	-57	-45.6	176.1	-68.1	166.9	0	0	0	110.7	I354 F355 Y361 F362	I354-I358 HydrophobicContact CG2-CD1 4Å; I354-I358 WeakPolarHBondContact O-CG1 3.3Å; I354-I358 PolarHBondContact O-N 3.46Å; F355-I358 PolarHBondContact O-N 3.34Å; I358-Y361 PolarHBondContact O-N 2.98Å; I358-F362 VanDerWaalsContact O-CB 3.25Å; I358-F362 WeakPolarHBondContact O-CB 3.44Å; I358-F362 PolarHBondContact O-N 3.22Å
359	I	90.6	Very high	81.3	Confident	34 Å²	34	70.1 Å²	70.1	17%	0.174	35%	0.351	C	S	.	.	H	α-helix	trans	-63.9	-44.1	177.7	-69.7	175.1	0	0	0	111.5	I249 W253 F355 G356 S357 Y361 F362 L363	I249-I359 HydrophobicContact CG2-CG2 3.75Å; W253-I359 HydrophobicContact CE3-CG2 4.32Å; W253-I359 HydrophobicContact CZ3-CG2 4Å; F355-I359 HydrophobicContact CD1-CD1 3.77Å; F355-I359 HydrophobicContact CE1-CD1 3.25Å; F355-I359 HydrophobicContact CE1-CG1 4.26Å; F355-I359 HydrophobicContact CE2-CD1 4.41Å; F355-I359 HydrophobicContact CZ-CD1 3.63Å; F355-I359 HydrophobicContact CZ-CG1 4.31Å; F355-I359 WeakPolarHBondContact O-CG1 3.31Å; F355-I359 PolarHBondContact O-N 2.91Å; G356-I359 PolarHBondContact O-N 3.38Å; S357-I359 VanDerWaalsContact C-N 3.31Å; S357-I359 PolarHBondContact O-N 3.3Å; I359-Y361 PolarHBondContact O-N 2.85Å; I359-F362 WeakPolarHBondContact O-CB 3.25Å; I359-F362 PolarHBondContact O-N 3.24Å; I359-L363 HydrophobicContact CG2-CD1 4.09Å; I359-L363 HydrophobicContact CG2-CG 4.31Å; I359-L363 WeakPolarHBondContact O-CG 3.39Å; I359-L363 PolarHBondContact O-N 3.13Å
360	R	89.4	Confident	83	Confident	49 Å²	49	65 Å²	65	19%	0.185	32%	0.324	C	S	.	.	H	α-helix	trans	-58.7	-48.2	178.2	-74.1	168.9	69.1	-170.7	4	111.3	W253 F343 L345 G356 S357 L363 V364	W253-R360 HydrophobicContact CH2-CG 3.78Å; W253-R360 HydrophobicContact CZ3-CG 4.2Å; F343-R360 HydrophobicContact CD2-CB 4.05Å; F343-R360 VanDerWaalsContact O-CZ 3.23Å; F343-R360 PolarHBondContact O-NE 3.41Å; F343-R360 PolarHBondContact O-NH2 3.15Å; L345-R360 PolarHBondContact O-NE 3.1Å; L345-R360 PolarHBondContact O-NH1 2.74Å; L345-R360 PolarHBondContact O-NH2 3Å; G356-R360 VanDerWaalsContact O-CG 3.27Å; G356-R360 WeakPolarHBondContact O-CG 3.39Å; G356-R360 PolarHBondContact O-N 3.07Å; S357-R360 PolarHBondContact O-N 3.49Å; R360-L363 PolarHBondContact O-N 3.4Å; R360-V364 PolarHBondContact O-N 2.83Å
361	Y	90.8	Very high	84.8	Confident	103 Å²	103	60.9 Å²	60.9	40%	0.404	30%	0.297	S	S	.	.	H	α-helix	trans	-66.7	-36.4	176.8	-82.8	-75.7	0	0	0	112.6	F343 S357 I358 I359 V364 L365	F343-Y361 HydrophobicContact CE2-CD1 4.02Å; F343-Y361 HydrophobicContact CE2-CD2 4.45Å; F343-Y361 AromaticContact CE2-CE1 3.87Å; F343-Y361 HydrophobicContact CE2-CE1 3.87Å; F343-Y361 HydrophobicContact CE2-CE2 4.31Å; F343-Y361 HydrophobicContact CE2-CG 4.32Å; F343-Y361 HydrophobicContact CZ-CE1 4.1Å; S357-Y361 WeakPolarHBondContact O-CD2 3.48Å; S357-Y361 PolarHBondContact O-N 3.04Å; I358-Y361 PolarHBondContact O-N 2.98Å; I359-Y361 PolarHBondContact O-N 2.85Å; Y361-V364 HydrophobicContact CD1-CG1 4.37Å; Y361-V364 WeakPolarHBondContact O-CG1 3.5Å; Y361-L365 VanDerWaalsContact O-CB 3.26Å; Y361-L365 WeakPolarHBondContact O-CB 3.31Å; Y361-L365 VanDerWaalsContact O-CG 3.24Å; Y361-L365 WeakPolarHBondContact O-CG 3.24Å; Y361-L365 PolarHBondContact O-N 2.69Å
362	F	93.6	Very high	86.5	Confident	57 Å²	57	52.9 Å²	52.9	25%	0.25	26%	0.262	C	S	.	.	H	α-helix	trans	-60.1	-47.4	173.6	172.2	-96.8	0	0	0	111.8	L242 L245 S246 I249 I358 I359 L365 Y366	L242-F362 HydrophobicContact CD2-CE2 3.76Å; L242-F362 HydrophobicContact CD2-CZ 4.13Å; L245-F362 HydrophobicContact CB-CZ 4.28Å; L245-F362 HydrophobicContact CD2-CE1 4.2Å; L245-F362 HydrophobicContact CD2-CE2 4.21Å; L245-F362 HydrophobicContact CD2-CZ 3.61Å; L245-F362 HydrophobicContact CG-CE1 4.03Å; L245-F362 HydrophobicContact CG-CZ 3.84Å; S246-F362 VanDerWaalsContact OG-CE1 3.22Å; S246-F362 WeakPolarHBondContact OG-CE1 3.22Å; I249-F362 HydrophobicContact CD1-CD1 4.11Å; I249-F362 HydrophobicContact CD1-CE1 3.93Å; I358-F362 VanDerWaalsContact O-CB 3.25Å; I358-F362 WeakPolarHBondContact O-CB 3.44Å; I358-F362 PolarHBondContact O-N 3.22Å; I359-F362 WeakPolarHBondContact O-CB 3.25Å; I359-F362 PolarHBondContact O-N 3.24Å; F362-L365 PolarHBondContact O-N 3.23Å; F362-Y366 PolarHBondContact O-N 3.14Å
363	L	93.4	Very high	87.9	Confident	0 Å²	0	48.7 Å²	48.7	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-66.9	-43.6	-179.7	-70.1	178.8	0	0	0	112.6	I249 M250 W253 V339 F342 I359 R360 L365 Y366 P367	I249-L363 HydrophobicContact CB-CD2 4.23Å; I249-L363 HydrophobicContact CG2-CD1 3.96Å; I249-L363 HydrophobicContact CG2-CD2 4.13Å; I249-L363 HydrophobicContact CG2-CG 4.35Å; M250-L363 HydrophobicContact CG-CD1 4.18Å; M250-L363 HydrophobicContact CG-CD2 3.88Å; W253-L363 HydrophobicContact CE3-CD1 4.11Å; W253-L363 HydrophobicContact CZ3-CD1 4.1Å; V339-L363 WeakPolarHBondContact CB-O 3.36Å; V339-L363 WeakPolarHBondContact CG1-O 3.3Å; F342-L363 HydrophobicContact CB-CD1 3.76Å; F342-L363 HydrophobicContact CD1-CD1 4.46Å; F342-L363 HydrophobicContact CD2-CD1 4.46Å; F342-L363 HydrophobicContact CG-CD1 3.99Å; I359-L363 HydrophobicContact CG2-CD1 4.09Å; I359-L363 HydrophobicContact CG2-CG 4.31Å; I359-L363 WeakPolarHBondContact O-CG 3.39Å; I359-L363 PolarHBondContact O-N 3.13Å; R360-L363 PolarHBondContact O-N 3.4Å; L363-L365 VanDerWaalsContact C-N 3.32Å; L363-L365 PolarHBondContact O-N 3.05Å; L363-Y366 WeakPolarHBondContact O-CB 3.26Å; L363-Y366 PolarHBondContact O-N 2.79Å; L363-P367 WeakPolarHBondContact O-CD 3.4Å
364	V	91.9	Very high	88.7	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-69.9	-29.6	179.8	77.6	0	0	0	0	112.1	S166 A170 L340 F343 R360 Y361 P367	S166-V364 WeakPolarHBondContact CB-O 3.25Å; S166-V364 WeakPolarHBondContact O-CG2 3.43Å; A170-V364 HydrophobicContact CB-CG1 3.85Å; A170-V364 HydrophobicContact CB-CG2 4.27Å; L340-V364 HydrophobicContact CD2-CG2 4.07Å; F343-V364 HydrophobicContact CB-CB 4.09Å; F343-V364 HydrophobicContact CB-CG2 4.19Å; F343-V364 HydrophobicContact CD2-CB 3.82Å; F343-V364 HydrophobicContact CD2-CG1 3.69Å; F343-V364 HydrophobicContact CD2-CG2 4.29Å; F343-V364 HydrophobicContact CE2-CG1 3.96Å; F343-V364 HydrophobicContact CG-CB 4.02Å; F343-V364 HydrophobicContact CG-CG1 4.32Å; F343-V364 HydrophobicContact CG-CG2 4.07Å; R360-V364 PolarHBondContact O-N 2.83Å; Y361-V364 HydrophobicContact CD1-CG1 4.37Å; Y361-V364 WeakPolarHBondContact O-CG1 3.5Å; V364-P367 WeakPolarHBondContact O-CD 3.31Å
365	L	92.5	Very high	89.3	Confident	47 Å²	47	40.2 Å²	40.2	25%	0.246	20%	0.199	C	C	.	.	H	α-helix	trans	-88.3	-12	177.4	-65.5	174.1	0	0	0	113.5	L167 Y361 F362 L363 V368 F369	L167-L365 HydrophobicContact CD1-CD2 4.21Å; Y361-L365 VanDerWaalsContact O-CB 3.26Å; Y361-L365 WeakPolarHBondContact O-CB 3.31Å; Y361-L365 VanDerWaalsContact O-CG 3.24Å; Y361-L365 WeakPolarHBondContact O-CG 3.24Å; Y361-L365 PolarHBondContact O-N 2.69Å; F362-L365 PolarHBondContact O-N 3.23Å; L363-L365 VanDerWaalsContact C-N 3.32Å; L363-L365 PolarHBondContact O-N 3.05Å; L365-V368 HydrophobicContact CD2-CG2 4.13Å; L365-V368 WeakPolarHBondContact O-CA 3.5Å; L365-V368 VanDerWaalsContact O-CB 3.27Å; L365-V368 WeakPolarHBondContact O-CB 3.48Å; L365-V368 PolarHBondContact O-N 3.45Å; L365-F369 HydrophobicContact CB-CD2 4.23Å; L365-F369 HydrophobicContact CB-CE2 3.77Å; L365-F369 WeakPolarHBondContact O-CD2 3.46Å; L365-F369 PolarHBondContact O-N 3.33Å; L365-F369 VanDerWaalsContact O-N 3.14Å
366	Y	91.5	Very high	89.6	Confident	6 Å²	6	33.9 Å²	33.9	2%	0.024	17%	0.172	C	C	.	.	H	α-helix	trans	-53	-47.4	178.1	151.6	-102.1	0	0	0	113.5	L26 L242 R243 S246 V339 F362 L363 V368 F369 T370	L26-Y366 HydrophobicContact CD1-CE1 4.28Å; L26-Y366 HydrophobicContact CD2-CE1 4.31Å; L242-Y366 HydrophobicContact CB-CD2 4.42Å; R243-Y366 HydrophobicContact CB-CE2 3.73Å; R243-Y366 HydrophobicContact CG-CE2 4.26Å; R243-Y366 VanDerWaalsContact CG-OH 3.31Å; R243-Y366 WeakPolarHBondContact CG-OH 3.16Å; S246-Y366 VanDerWaalsContact OG-CB 3.3Å; S246-Y366 WeakPolarHBondContact OG-CB 3.33Å; S246-Y366 WeakPolarHBondContact OG-CD2 3.35Å; S246-Y366 VanDerWaalsContact OG-CG 3.23Å; V339-Y366 HydrophobicContact CG1-CD1 4.13Å; F362-Y366 PolarHBondContact O-N 3.14Å; L363-Y366 WeakPolarHBondContact O-CB 3.26Å; L363-Y366 PolarHBondContact O-N 2.79Å; Y366-V368 VanDerWaalsContact C-N 3.27Å; Y366-V368 PolarHBondContact O-N 3.4Å; Y366-F369 PolarHBondContact O-N 3.05Å; Y366-T370 HydrophobicContact CD2-CG2 3.57Å; Y366-T370 HydrophobicContact CE2-CG2 3.32Å; Y366-T370 WeakPolarHBondContact CE2-OG1 3.48Å; Y366-T370 PolarHBondContact O-N 2.91Å; Y366-T370 PolarHBondContact O-OG1 3.49Å
367	P	90.6	Very high	89.7	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-61.9	-38.9	176.4	-21.6	34.2	0	0	0	111.2	L26 V162 V339 L363 V364 F369 T370 I371	L26-P367 HydrophobicContact CD1-CG 4.46Å; V162-P367 HydrophobicContact CG1-CB 3.83Å; V339-P367 HydrophobicContact CG1-CG 4.39Å; V339-P367 HydrophobicContact CG2-CG 3.72Å; L363-P367 WeakPolarHBondContact O-CD 3.4Å; V364-P367 WeakPolarHBondContact O-CD 3.31Å; P367-F369 VanDerWaalsContact C-N 3.28Å; P367-F369 PolarHBondContact O-N 3.49Å; P367-T370 PolarHBondContact O-N 3.36Å; P367-I371 HydrophobicContact CB-CD1 3.7Å; P367-I371 HydrophobicContact CB-CG1 4.3Å; P367-I371 WeakPolarHBondContact O-CA 3.47Å; P367-I371 WeakPolarHBondContact O-CB 3.45Å; P367-I371 WeakPolarHBondContact O-CG1 3.46Å; P367-I371 PolarHBondContact O-N 3.25Å
368	V	91.8	Very high	90	Very high	26 Å²	26	34.2 Å²	34.2	16%	0.158	17%	0.166	C	C	.	.	H	α-helix	trans	-57.2	-41.2	178.7	-174.9	0	0	0	0	111.2	V163 L167 L365 Y366 S372	V163-V368 HydrophobicContact CG1-CB 4.38Å; V163-V368 HydrophobicContact CG1-CG1 4.15Å; V163-V368 HydrophobicContact CG1-CG2 4.25Å; L167-V368 HydrophobicContact CB-CG2 4.46Å; L365-V368 HydrophobicContact CD2-CG2 4.13Å; L365-V368 WeakPolarHBondContact O-CA 3.5Å; L365-V368 VanDerWaalsContact O-CB 3.27Å; L365-V368 WeakPolarHBondContact O-CB 3.48Å; L365-V368 PolarHBondContact O-N 3.45Å; Y366-V368 VanDerWaalsContact C-N 3.27Å; Y366-V368 PolarHBondContact O-N 3.4Å; V368-S372 WeakPolarHBondContact O-CB 3.26Å; V368-S372 PolarHBondContact O-OG 3.43Å
369	F	88	Confident	90.1	Very high	128 Å²	128	29.2 Å²	29.2	56%	0.561	14%	0.141	S	C	*	.	H	α-helix	trans	-79.5	-45	179.1	-65.2	-63.3	0	0	0	113.2	L242 L365 Y366 P367 S373	L242-F369 HydrophobicContact CD1-CB 4.29Å; L365-F369 HydrophobicContact CB-CD2 4.23Å; L365-F369 HydrophobicContact CB-CE2 3.77Å; L365-F369 WeakPolarHBondContact O-CD2 3.46Å; L365-F369 PolarHBondContact O-N 3.33Å; L365-F369 VanDerWaalsContact O-N 3.14Å; Y366-F369 PolarHBondContact O-N 3.05Å; P367-F369 VanDerWaalsContact C-N 3.28Å; P367-F369 PolarHBondContact O-N 3.49Å; F369-S373 PolarHBondContact O-N 3.49Å; F369-S373 PolarHBondContact O-OG 3.43Å
370	T	88.1	Confident	90	Very high	2 Å²	2	27.7 Å²	27.7	1%	0.012	13%	0.133	C	C	.	.	H	α-helix	trans	-85.3	-31.7	-168.5	60.4	0	0	0	0	114.1	A239 L242 Y366 P367 S373	A239-T370 HydrophobicContact CB-CG2 3.91Å; L242-T370 HydrophobicContact CB-CG2 3.99Å; L242-T370 HydrophobicContact CD1-CG2 4.42Å; Y366-T370 HydrophobicContact CD2-CG2 3.57Å; Y366-T370 HydrophobicContact CE2-CG2 3.32Å; Y366-T370 WeakPolarHBondContact CE2-OG1 3.48Å; Y366-T370 PolarHBondContact O-N 2.91Å; Y366-T370 PolarHBondContact O-OG1 3.49Å; P367-T370 PolarHBondContact O-N 3.36Å; T370-S373 PolarHBondContact O-OG 2.82Å
371	I	90.4	Very high	90	Very high	4 Å²	4	27.9 Å²	27.9	2%	0.021	14%	0.139	C	C	.	.	H	α-helix	trans	-80.1	-42.5	176.3	-60.2	-179.5	0	0	0	109.8	T23 Y159 V162 V163 P367 S373 N374 Y375	T23-I371 HydrophobicContact CG2-CD1 3.49Å; T23-I371 VanDerWaalsContact CG2-CD1 3.49Å; T23-I371 HydrophobicContact CG2-CG1 3.79Å; Y159-I371 VanDerWaalsContact CB-CG2 3.44Å; Y159-I371 HydrophobicContact CD1-CG2 3.55Å; Y159-I371 HydrophobicContact CD2-CG2 3.28Å; Y159-I371 HydrophobicContact CE1-CG2 4.1Å; Y159-I371 HydrophobicContact CE2-CG2 3.81Å; Y159-I371 HydrophobicContact CG-CG2 3.12Å; V162-I371 HydrophobicContact CB-CD1 4Å; V162-I371 HydrophobicContact CG1-CD1 3.44Å; V162-I371 VanDerWaalsContact CG1-CD1 3.44Å; V163-I371 HydrophobicContact CG2-CB 3.78Å; V163-I371 HydrophobicContact CG2-CG2 3.83Å; P367-I371 HydrophobicContact CB-CD1 3.7Å; P367-I371 HydrophobicContact CB-CG1 4.3Å; P367-I371 WeakPolarHBondContact O-CA 3.47Å; P367-I371 WeakPolarHBondContact O-CB 3.45Å; P367-I371 WeakPolarHBondContact O-CG1 3.46Å; P367-I371 PolarHBondContact O-N 3.25Å; I371-S373 VanDerWaalsContact C-N 3.25Å; I371-S373 PolarHBondContact O-N 3.1Å; I371-N374 PolarHBondContact O-N 3.37Å; I371-Y375 PolarHBondContact O-N 2.95Å
372	S	89.6	Confident	90.1	Very high	22 Å²	22	23.1 Å²	23.1	15%	0.154	12%	0.121	C	C	.	.	H	α-helix	trans	-59.9	-34.5	177.3	-60.4	0	0	0	0	112.7	V368 N374 Y375 P376	V368-S372 WeakPolarHBondContact O-CB 3.26Å; V368-S372 PolarHBondContact O-OG 3.43Å; S372-N374 VanDerWaalsContact C-N 3.26Å; S372-N374 PolarHBondContact O-N 2.88Å; S372-Y375 PolarHBondContact O-N 2.85Å; S372-P376 WeakPolarHBondContact O-CD 3.32Å
373	S	85.3	Confident	89.9	Confident	24 Å²	24	22.4 Å²	22.4	17%	0.168	12%	0.117	C	C	.	.	H	α-helix	trans	-66.3	-28.5	174.7	60.5	0	0	0	0	113.3	F369 T370 I371	F369-S373 PolarHBondContact O-N 3.49Å; F369-S373 PolarHBondContact O-OG 3.43Å; T370-S373 PolarHBondContact O-OG 2.82Å; I371-S373 VanDerWaalsContact C-N 3.25Å; I371-S373 PolarHBondContact O-N 3.1Å
374	N	86.5	Confident	89.6	Confident	31 Å²	31	29.1 Å²	29.1	17%	0.166	14%	0.142	C	C	.	.	H	α-helix	trans	-87.9	-27.6	-179.3	-69.2	-9.1	0	0	0	112.5	Y159 I371 S372 I377 I378	Y159-N374 HydrophobicContact CE2-CB 3.73Å; I371-N374 PolarHBondContact O-N 3.37Å; S372-N374 VanDerWaalsContact C-N 3.26Å; S372-N374 PolarHBondContact O-N 2.88Å; N374-I377 WeakPolarHBondContact O-CB 3.43Å; N374-I377 PolarHBondContact O-N 3.34Å; N374-I378 PolarHBondContact O-N 3.5Å
375	Y	91.1	Very high	89.4	Confident	0 Å²	0	30.1 Å²	30.1	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-53.4	-49.8	-175	-176	-88.7	0	0	0	113.6	L156 Y159 F217 L221 I371 S372 I377 I378 G379	L156-Y375 HydrophobicContact CB-CE2 3.97Å; L156-Y375 HydrophobicContact CD2-CD1 4.45Å; L156-Y375 HydrophobicContact CD2-CD2 3.55Å; L156-Y375 HydrophobicContact CD2-CE1 4.41Å; L156-Y375 HydrophobicContact CD2-CE2 3.52Å; L156-Y375 HydrophobicContact CD2-CG 4.05Å; L156-Y375 WeakPolarHBondContact CD2-O 3.28Å; L156-Y375 HydrophobicContact CG-CE2 4.33Å; L156-Y375 WeakPolarHBondContact O-CE2 3.48Å; Y159-Y375 HydrophobicContact CD2-CD2 4.24Å; Y159-Y375 HydrophobicContact CG-CD2 4.47Å; F217-Y375 HydrophobicContact CE1-CD1 4.18Å; F217-Y375 AromaticContact CE1-CD2 3.7Å; F217-Y375 HydrophobicContact CE1-CD2 3.7Å; F217-Y375 HydrophobicContact CE1-CE1 4.07Å; F217-Y375 AromaticContact CE1-CE2 3.55Å; F217-Y375 HydrophobicContact CE1-CE2 3.55Å; F217-Y375 HydrophobicContact CE1-CG 4.01Å; F217-Y375 AromaticContact CE1-CZ 3.75Å; F217-Y375 HydrophobicContact CZ-CD1 4.2Å; F217-Y375 AromaticContact CZ-CD2 3.6Å; F217-Y375 HydrophobicContact CZ-CD2 3.6Å; F217-Y375 AromaticContact CZ-CE2 3.97Å; F217-Y375 HydrophobicContact CZ-CE2 3.97Å; F217-Y375 AromaticContact CZ-CG 3.72Å; F217-Y375 HydrophobicContact CZ-CG 3.72Å; L221-Y375 HydrophobicContact CB-CD1 3.94Å; L221-Y375 HydrophobicContact CB-CE1 4.4Å; L221-Y375 HydrophobicContact CD1-CD1 4.31Å; L221-Y375 HydrophobicContact CD1-CG 4.43Å; I371-Y375 PolarHBondContact O-N 2.95Å; S372-Y375 PolarHBondContact O-N 2.85Å; Y375-I377 VanDerWaalsContact C-N 3.31Å; Y375-I377 PolarHBondContact O-N 2.96Å; Y375-I378 PolarHBondContact O-N 3.23Å; Y375-G379 PolarHBondContact O-N 3Å
376	P	89.4	Confident	89.3	Confident	14 Å²	14	28.7 Å²	28.7	9%	0.091	14%	0.14	C	C	.	.	H	α-helix	trans	-62.8	-35.3	177.5	-24.4	35.3	0	0	0	113.8	F224 S372 G379 I380	F224-P376 HydrophobicContact CB-CB 3.67Å; F224-P376 HydrophobicContact CB-CG 3.74Å; F224-P376 HydrophobicContact CG-CG 4.33Å; S372-P376 WeakPolarHBondContact O-CD 3.32Å; P376-G379 PolarHBondContact O-N 2.84Å; P376-I380 WeakPolarHBondContact O-CD1 3.39Å; P376-I380 WeakPolarHBondContact O-CG1 3.32Å; P376-I380 PolarHBondContact O-N 2.98Å
377	I	86.7	Confident	89.1	Confident	44 Å²	44	30 Å²	30	23%	0.226	15%	0.147	C	C	.	.	H	α-helix	trans	-66	-46.2	-178.4	-54.4	173.3	0	0	0	109.8	T232 N374 Y375 I380 T381	T232-I377 HydrophobicContact CG2-CD1 4.24Å; T232-I377 HydrophobicContact CG2-CG1 4.44Å; T232-I377 VanDerWaalsContact OG1-CD1 3.23Å; T232-I377 WeakPolarHBondContact OG1-CD1 3.43Å; N374-I377 WeakPolarHBondContact O-CB 3.43Å; N374-I377 PolarHBondContact O-N 3.34Å; Y375-I377 VanDerWaalsContact C-N 3.31Å; Y375-I377 PolarHBondContact O-N 2.96Å; I377-I380 PolarHBondContact O-N 3.44Å; I377-T381 WeakPolarHBondContact O-CB 3.41Å; I377-T381 PolarHBondContact O-N 2.98Å; I377-T381 PolarHBondContact O-OG1 3.12Å
378	I	89.2	Confident	88.7	Confident	22 Å²	22	31.9 Å²	31.9	11%	0.113	16%	0.159	C	C	.	.	H	α-helix	trans	-64.6	-42.6	176	-62.2	-177.1	0	0	0	109.7	L152 D155 L156 Y159 N374 Y375 I380 T381 L382	L152-I378 HydrophobicContact CB-CG2 4.32Å; L152-I378 HydrophobicContact CD2-CG2 3.96Å; D155-I378 HydrophobicContact CB-CD1 4.01Å; D155-I378 HydrophobicContact CB-CG2 3.97Å; L156-I378 HydrophobicContact CD1-CG2 4.5Å; L156-I378 HydrophobicContact CD2-CB 3.9Å; L156-I378 HydrophobicContact CD2-CG2 3.76Å; L156-I378 HydrophobicContact CG-CB 4.49Å; L156-I378 HydrophobicContact CG-CG2 3.8Å; Y159-I378 HydrophobicContact CD2-CD1 4.16Å; Y159-I378 HydrophobicContact CE2-CD1 3.35Å; Y159-I378 HydrophobicContact CE2-CG1 4.5Å; N374-I378 PolarHBondContact O-N 3.5Å; Y375-I378 PolarHBondContact O-N 3.23Å; I378-I380 PolarHBondContact O-N 2.03Å; I378-T381 CarbonylContact O-C 3.59Å; I378-T381 WeakPolarHBondContact O-CB 3.34Å; I378-T381 PolarHBondContact O-N 2.88Å; I378-T381 VanDerWaalsContact O-N 3.1Å; I378-L382 WeakPolarHBondContact O-CB 3.32Å; I378-L382 PolarHBondContact O-N 3.31Å
379	G	92.2	Very high	88.4	Confident	0 Å²	0	31.8 Å²	31.8	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-57.9	-46.5	175.5	0	0	0	0	0	113	Y375 P376 T381 L382 R383 V449	Y375-G379 PolarHBondContact O-N 3Å; P376-G379 PolarHBondContact O-N 2.84Å; G379-T381 VanDerWaalsContact C-N 3.29Å; G379-T381 PolarHBondContact O-N 3.34Å; G379-L382 PolarHBondContact O-N 2.86Å; G379-R383 WeakPolarHBondContact O-CB 3.5Å; G379-R383 PolarHBondContact O-N 3.38Å; G379-V449 WeakPolarHBondContact O-CG1 3.38Å
380	I	88.8	Confident	88.2	Confident	3 Å²	3	32.9 Å²	32.9	2%	0.015	16%	0.162	C	C	.	.	H	α-helix	trans	-63.4	-38.3	176	-66.8	159.6	0	0	0	110.9	P376 I377 I378 R384	P376-I380 WeakPolarHBondContact O-CD1 3.39Å; P376-I380 WeakPolarHBondContact O-CG1 3.32Å; P376-I380 PolarHBondContact O-N 2.98Å; I377-I380 PolarHBondContact O-N 3.44Å; I378-I380 PolarHBondContact O-N 2.03Å; I380-R384 WeakPolarHBondContact O-CG 3.35Å; I380-R384 PolarHBondContact O-N 2.81Å
381	T	88.4	Confident	87.7	Confident	52 Å²	52	35.8 Å²	35.8	32%	0.319	17%	0.174	S	C	.	.	H	α-helix	trans	-67.8	-44.5	178.7	-55.7	0	0	0	0	111.2	L152 I377 I378 G379 R384 N385	L152-T381 HydrophobicContact CD1-CG2 3.84Å; L152-T381 HydrophobicContact CD2-CG2 4.47Å; I377-T381 WeakPolarHBondContact O-CB 3.41Å; I377-T381 PolarHBondContact O-N 2.98Å; I377-T381 PolarHBondContact O-OG1 3.12Å; I378-T381 CarbonylContact O-C 3.59Å; I378-T381 WeakPolarHBondContact O-CB 3.34Å; I378-T381 PolarHBondContact O-N 2.88Å; I378-T381 VanDerWaalsContact O-N 3.1Å; G379-T381 VanDerWaalsContact C-N 3.29Å; G379-T381 PolarHBondContact O-N 3.34Å; T381-R384 PolarHBondContact O-N 3.4Å; T381-N385 PolarHBondContact O-N 3.43Å; T381-N385 PolarHBondContact O-ND2 3.11Å
382	L	92.3	Very high	86.8	Confident	3 Å²	3	38.6 Å²	38.6	2%	0.016	20%	0.195	C	C	.	.	H	α-helix	trans	-59.7	-48.2	174.3	177.6	55.7	0	0	0	110.6	I149 L152 F153 L156 I378 G379 R384 N385 I386 V449	I149-L382 HydrophobicContact CB-CD1 4.11Å; I149-L382 HydrophobicContact CG1-CD1 4.15Å; I149-L382 HydrophobicContact CG2-CD1 3.89Å; I149-L382 WeakPolarHBondContact O-CD1 3.46Å; L152-L382 HydrophobicContact CB-CB 4.04Å; L152-L382 HydrophobicContact CB-CD1 4.02Å; L152-L382 HydrophobicContact CB-CG 4.45Å; L152-L382 HydrophobicContact CD1-CB 4.38Å; F153-L382 HydrophobicContact CB-CD2 4.25Å; L156-L382 HydrophobicContact CD1-CB 4.4Å; L156-L382 HydrophobicContact CD1-CD2 3.61Å; I378-L382 WeakPolarHBondContact O-CB 3.32Å; I378-L382 PolarHBondContact O-N 3.31Å; G379-L382 PolarHBondContact O-N 2.86Å; L382-R384 VanDerWaalsContact C-N 3.3Å; L382-R384 PolarHBondContact O-N 3.37Å; L382-N385 PolarHBondContact O-N 3.44Å; L382-N385 VanDerWaalsContact O-N 3.1Å; L382-I386 HydrophobicContact CD1-CD1 3.83Å; L382-I386 HydrophobicContact CD1-CG1 3.97Å; L382-I386 HydrophobicContact CG-CD1 3.86Å; L382-I386 HydrophobicContact CG-CG1 4.41Å; L382-I386 WeakPolarHBondContact O-CG1 3.39Å; L382-I386 PolarHBondContact O-N 2.91Å; L382-V449 HydrophobicContact CB-CG1 4.32Å; L382-V449 HydrophobicContact CD2-CG1 4.11Å; L382-V449 HydrophobicContact CD2-CG2 4.26Å; L382-V449 HydrophobicContact CG-CG1 4.33Å; L382-V449 HydrophobicContact CG-CG2 4.06Å
383	R	90.4	Very high	85.1	Confident	42 Å²	42	40.2 Å²	40.2	16%	0.158	21%	0.209	C	C	.	.	H	α-helix	trans	-52.7	-47.5	174.8	177.6	176.1	72.1	175	-2.6	111.7	V225 F226 G379 I386 D387 L445 V449	V225-R383 VanDerWaalsContact O-CZ 3.27Å; V225-R383 PolarHBondContact O-NH1 2.92Å; V225-R383 PolarHBondContact O-NH2 3.37Å; F226-R383 PolarHBondContact O-NH1 2.78Å; G379-R383 WeakPolarHBondContact O-CB 3.5Å; G379-R383 PolarHBondContact O-N 3.38Å; R383-I386 PolarHBondContact O-N 3.13Å; R383-D387 VanDerWaalsContact O-CB 3.26Å; R383-D387 WeakPolarHBondContact O-CB 3.36Å; R383-D387 PolarHBondContact O-N 3.13Å; R383-L445 HydrophobicContact CG-CD2 3.71Å; R383-L445 HydrophobicContact CG-CG 3.93Å; R383-V449 HydrophobicContact CB-CG2 4.22Å
384	R	86.6	Confident	83.7	Confident	142 Å²	142	41.8 Å²	41.8	54%	0.536	22%	0.216	S	C	.	.	H	α-helix	trans	-65.4	-38.8	178.7	-73.9	175.9	178.3	176.3	1	112.6	I380 T381 L382 D387 T388	I380-R384 WeakPolarHBondContact O-CG 3.35Å; I380-R384 PolarHBondContact O-N 2.81Å; T381-R384 PolarHBondContact O-N 3.4Å; L382-R384 VanDerWaalsContact C-N 3.3Å; L382-R384 PolarHBondContact O-N 3.37Å; R384-D387 PolarHBondContact O-N 2.97Å; R384-T388 WeakPolarHBondContact O-CB 3.19Å; R384-T388 PolarHBondContact O-N 3.47Å; R384-T388 PolarHBondContact O-OG1 3.45Å; R384-T388 VanDerWaalsContact O-OG1 3.05Å
385	N	88.9	Confident	82.1	Confident	21 Å²	21	42 Å²	42	11%	0.112	22%	0.219	C	C	.	.	H	α-helix	trans	-67.7	-41.4	177.8	-80.8	-88	0	0	0	111.9	Y145 I149 T381 L382 D387 T388 L389	Y145-N385 HydrophobicContact CD1-CB 4.19Å; Y145-N385 WeakPolarHBondContact CD1-OD1 3.32Å; Y145-N385 HydrophobicContact CE1-CB 4.47Å; Y145-N385 WeakPolarHBondContact CE1-OD1 3.41Å; I149-N385 HydrophobicContact CG1-CB 3.97Å; T381-N385 PolarHBondContact O-N 3.43Å; T381-N385 PolarHBondContact O-ND2 3.11Å; L382-N385 PolarHBondContact O-N 3.44Å; L382-N385 VanDerWaalsContact O-N 3.1Å; N385-D387 VanDerWaalsContact C-N 3.33Å; N385-T388 PolarHBondContact O-N 3.5Å; N385-L389 WeakPolarHBondContact O-CB 3.24Å; N385-L389 PolarHBondContact O-N 2.89Å
386	I	90.2	Very high	79.9	Confident	16 Å²	16	46.2 Å²	46.2	8%	0.082	25%	0.248	C	C	.	.	H	α-helix	trans	-63.4	-43.4	172.8	-62.5	170.5	0	0	0	109.9	I149 L382 R383 T388 L389 F390 L445 V449	I149-I386 HydrophobicContact CD1-CB 4.44Å; I149-I386 HydrophobicContact CD1-CG1 3.87Å; I149-I386 HydrophobicContact CG1-CG1 3.9Å; I149-I386 HydrophobicContact CG2-CG1 4.09Å; L382-I386 HydrophobicContact CD1-CD1 3.83Å; L382-I386 HydrophobicContact CD1-CG1 3.97Å; L382-I386 HydrophobicContact CG-CD1 3.86Å; L382-I386 HydrophobicContact CG-CG1 4.41Å; L382-I386 WeakPolarHBondContact O-CG1 3.39Å; L382-I386 PolarHBondContact O-N 2.91Å; R383-I386 PolarHBondContact O-N 3.13Å; I386-T388 VanDerWaalsContact C-N 3.33Å; I386-T388 PolarHBondContact O-N 3.03Å; I386-L389 PolarHBondContact O-N 2.91Å; I386-F390 HydrophobicContact CG2-CD2 3.47Å; I386-F390 VanDerWaalsContact CG2-CD2 3.47Å; I386-F390 HydrophobicContact CG2-CE2 3.75Å; I386-F390 WeakPolarHBondContact O-CD2 3.47Å; I386-F390 PolarHBondContact O-N 2.92Å; I386-L445 HydrophobicContact CB-CD1 3.82Å; I386-L445 HydrophobicContact CD1-CD1 3.97Å; I386-L445 HydrophobicContact CG2-CD1 3.33Å; I386-L445 HydrophobicContact CG2-CD2 4.41Å; I386-L445 HydrophobicContact CG2-CG 4.5Å; I386-V449 HydrophobicContact CD1-CG2 3.72Å
387	D	85.6	Confident	77.7	Confident	33 Å²	33	53.8 Å²	53.8	18%	0.176	28%	0.28	C	S	.	.	H	α-helix	trans	-58.9	-45.7	178.6	-171.7	63.9	0	0	0	111.9	R383 R384 N385 F391 R441 L445	R383-D387 VanDerWaalsContact O-CB 3.26Å; R383-D387 WeakPolarHBondContact O-CB 3.36Å; R383-D387 PolarHBondContact O-N 3.13Å; R384-D387 PolarHBondContact O-N 2.97Å; N385-D387 VanDerWaalsContact C-N 3.33Å; D387-F391 WeakPolarHBondContact O-CA 3.41Å; D387-F391 WeakPolarHBondContact O-CB 3.15Å; D387-F391 PolarHBondContact O-N 2.75Å; D387-F391 WeakPolarHBondContact OD1-CD2 3.48Å; D387-R441 IonicContact OD1-CZ 2.7Å; D387-R441 IonicContact OD1-NE 2.72Å; D387-R441 PolarHBondContact OD1-NE 3.2Å; D387-R441 IonicContact OD1-NH2 3.04Å; D387-R441 PolarHBondContact OD1-NH2 2.93Å; D387-R441 IonicContact OD2-CZ 3.99Å; D387-R441 IonicContact OD2-NE 3.35Å; D387-R441 IonicContact OD2-NH2 2.83Å; D387-R441 PolarHBondContact OD2-NH2 3.21Å; D387-L445 HydrophobicContact CB-CD2 4.15Å
388	T	83.4	Confident	75.4	Confident	40 Å²	40	58.6 Å²	58.6	25%	0.245	30%	0.299	C	S	.	.	H	α-helix	trans	-62.1	-41.8	174.9	-64.4	0	0	0	0	112.2	W141 Y145 R384 N385 I386 S392	W141-T388 WeakPolarHBondContact CH2-O 3.19Å; W141-T388 HydrophobicContact CZ2-CG2 3.72Å; Y145-T388 HydrophobicContact CD1-CG2 4.3Å; Y145-T388 HydrophobicContact CE1-CG2 3.64Å; Y145-T388 HydrophobicContact CE2-CG2 4.19Å; R384-T388 WeakPolarHBondContact O-CB 3.19Å; R384-T388 PolarHBondContact O-N 3.47Å; R384-T388 PolarHBondContact O-OG1 3.45Å; R384-T388 VanDerWaalsContact O-OG1 3.05Å; N385-T388 PolarHBondContact O-N 3.5Å; I386-T388 VanDerWaalsContact C-N 3.33Å; I386-T388 PolarHBondContact O-N 3.03Å; T388-S392 WeakPolarHBondContact O-CB 3.18Å; T388-S392 PolarHBondContact O-N 3.24Å
389	L	86	Confident	73	Confident	25 Å²	25	65.2 Å²	65.2	13%	0.131	33%	0.329	C	S	.	.	H	α-helix	trans	-67.9	-42.8	-178.6	-171.6	63.3	0	0	0	113.1	W141 L142 I149 N385 I386	W141-L389 HydrophobicContact CH2-CD1 4.07Å; W141-L389 HydrophobicContact CZ3-CD1 3.83Å; L142-L389 HydrophobicContact CD1-CD1 3.56Å; I149-L389 HydrophobicContact CD1-CB 3.99Å; I149-L389 HydrophobicContact CD1-CD2 3.42Å; I149-L389 VanDerWaalsContact CD1-CD2 3.42Å; I149-L389 HydrophobicContact CD1-CG 4.33Å; N385-L389 WeakPolarHBondContact O-CB 3.24Å; N385-L389 PolarHBondContact O-N 2.89Å; I386-L389 PolarHBondContact O-N 2.91Å
390	F	84.2	Confident	70.1	Confident	150 Å²	150	68.9 Å²	68.9	66%	0.658	35%	0.353	S	S	*	.	H	α-helix	trans	-96.7	-29.3	-172.4	-72.5	-77.7	0	0	0	114.6	I386	I386-F390 HydrophobicContact CG2-CD2 3.47Å; I386-F390 VanDerWaalsContact CG2-CD2 3.47Å; I386-F390 HydrophobicContact CG2-CE2 3.75Å; I386-F390 WeakPolarHBondContact O-CD2 3.47Å; I386-F390 PolarHBondContact O-N 2.92Å
391	F	77.5	Confident	67.5	Low	63 Å²	63	75.2 Å²	75.2	28%	0.276	39%	0.393	S	S	.	.	H	α-helix	trans	-113.1	-13.4	-173.6	-57.2	-73.7	0	0	0	114.4	D387 A393 R437 L440 R441	D387-F391 WeakPolarHBondContact O-CA 3.41Å; D387-F391 WeakPolarHBondContact O-CB 3.15Å; D387-F391 PolarHBondContact O-N 2.75Å; D387-F391 WeakPolarHBondContact OD1-CD2 3.48Å; F391-A393 PolarHBondContact O-N 3.25Å; F391-R437 HydrophobicContact CD1-CG 4.28Å; F391-R437 HydrophobicContact CE1-CG 4.42Å; F391-L440 HydrophobicContact CE1-CD2 3.73Å; F391-L440 HydrophobicContact CZ-CD2 3.5Å; F391-L440 HydrophobicContact CZ-CG 3.99Å; F391-R441 HydrophobicContact CD2-CG 3.96Å; F391-R441 HydrophobicContact CE1-CG 4.48Å; F391-R441 HydrophobicContact CE2-CG 3.8Å; F391-R441 HydrophobicContact CG-CG 4.37Å; F391-R441 HydrophobicContact CZ-CG 4.09Å
392	S	70.1	Confident	64.9	Low	64 Å²	64	77.4 Å²	77.4	45%	0.448	42%	0.416	S	S	.	.	S	Bend	trans	-74.1	112.9	172.9	-149.6	0	0	0	0	108.6	T388 N394	T388-S392 WeakPolarHBondContact O-CB 3.18Å; T388-S392 PolarHBondContact O-N 3.24Å; S392-N394 PolarHBondContact O-N 3.32Å
393	A	55	Low	62.1	Low	56 Å²	56	84.3 Å²	84.3	46%	0.463	44%	0.441	S	S	.	.			trans	-51.8	132.8	173.4	0	0	0	0	0	108.7	F391	F391-A393 PolarHBondContact O-N 3.25Å
394	N	55.4	Low	59.4	Low	57 Å²	57	87.2 Å²	87.2	31%	0.305	45%	0.453	S	S	.	.			trans	-30.7	113	-176.6	-171.5	-10.3	0	0	0	110.5	Y138 S392 S396 K397	Y138-N394 WeakPolarHBondContact CD2-OD1 2.89Å; S392-N394 PolarHBondContact O-N 3.32Å; N394-S396 VanDerWaalsContact CG-OG 3.28Å; N394-S396 PolarHBondContact ND2-OG 2.85Å; N394-S396 PolarHBondContact O-N 2.86Å; N394-S396 PolarHBondContact OD1-N 3.5Å; N394-S396 PolarHBondContact OD1-OG 3.43Å; N394-S396 VanDerWaalsContact OD1-OG 3.09Å; N394-K397 PolarHBondContact O-N 3.02Å
395	P	53.8	Low	56.7	Low	34 Å²	34	85 Å²	85	22%	0.221	47%	0.474	C	S	.	.	G	3₁₀ helix	trans	-57.5	-20.9	-170.1	19.4	-32.3	0	0	0	112.8	N133 Y138 W141 K397	N133-P395 WeakPolarHBondContact OD1-CG 3.06Å; Y138-P395 HydrophobicContact CD2-CG 4.48Å; W141-P395 HydrophobicContact CD2-CG 4.43Å; P395-K397 PolarHBondContact O-N 3.22Å
396	S	44.1	Very low	53.9	Low	89 Å²	89	90.8 Å²	90.8	62%	0.622	51%	0.505	S	S	*	.	G	3₁₀ helix	trans	-66.4	-10.4	173.3	69.1	0	0	0	0	115.2	N394	N394-S396 VanDerWaalsContact CG-OG 3.28Å; N394-S396 PolarHBondContact ND2-OG 2.85Å; N394-S396 PolarHBondContact O-N 2.86Å; N394-S396 PolarHBondContact OD1-N 3.5Å; N394-S396 PolarHBondContact OD1-OG 3.43Å; N394-S396 VanDerWaalsContact OD1-OG 3.09Å
397	K	42.9	Very low	51	Low	174 Å²	174	94.9 Å²	94.9	76%	0.757	54%	0.541	S	S	*	.	G	3₁₀ helix	trans	-104.1	6.6	-178.9	-69.3	-170.5	175.8	-174.5	0	114.9	N394 P395	N394-K397 PolarHBondContact O-N 3.02Å; P395-K397 PolarHBondContact O-N 3.22Å
398	K	38.2	Very low	48.3	Very low	144 Å²	144	98.2 Å²	98.2	63%	0.626	56%	0.563	S	S	*	*			trans	-120.8	8	-169.6	-98.3	-168.3	175.9	-167.5	0	118.3
399	E	38.7	Very low	45.9	Very low	161 Å²	161	105 Å²	105	75%	0.752	59%	0.591	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.8	129.3	159.8	-77.5	-175.7	142.9	0	0	108.4
400	P	32.9	Very low	43.2	Very low	77 Å²	77	108.5 Å²	108.5	50%	0.5	61%	0.614	S	S	.	*	T	Hydrogen-bonded Turn	cis	-143.4	62.5	31.7	38.4	-15.1	0	0	0	115.7
401	T	32.3	Very low	40.8	Very low	137 Å²	137	107.7 Å²	107.7	84%	0.84	62%	0.616	S	S	*	*	T	Hydrogen-bonded Turn	trans	-127.1	-13.9	175.5	48.9	0	0	0	0	116.7	R403	T401-R403 PolarHBondContact O-N 3.09Å
402	A	33.8	Very low	38.9	Very low	97 Å²	97	110 Å²	110	80%	0.802	64%	0.635	S	S	*	*	S	Bend	trans	-87.2	27.6	174.3	0	0	0	0	0	113.3	Y404	A402-Y404 PolarHBondContact O-N 3.32Å
403	R	33.6	Very low	37.2	Very low	148 Å²	148	110.2 Å²	110.2	56%	0.558	63%	0.634	S	S	*	*			trans	-74	-17	-150.2	-155.3	173.7	-153.1	-178.6	7.6	116.8	T401	T401-R403 PolarHBondContact O-N 3.09Å
404	Y	33.5	Very low	36.4	Very low	104 Å²	104	110.4 Å²	110.4	41%	0.408	63%	0.632	S	S	.	*	S	Bend	trans	-155.6	85.9	-173.6	-62.9	-77.8	0	0	0	113.4	R73 S76 A402 L406	R73-Y404 HydrophobicContact CG-CE1 4.48Å; S76-Y404 WeakPolarHBondContact CB-OH 3.19Å; S76-Y404 PolarHBondContact OG-OH 3.1Å; A402-Y404 PolarHBondContact O-N 3.32Å; Y404-L406 WeakPolarHBondContact O-CB 3.21Å; Y404-L406 PolarHBondContact O-N 3.27Å
405	G	31	Very low	35.8	Very low	95 Å²	95	110 Å²	110	98%	0.979	63%	0.633	S	S	*	*	S	Bend	trans	47.6	16.8	149.4	0	0	0	0	0	120.3
406	L	30.5	Very low	35.1	Very low	143 Å²	143	114.5 Å²	114.5	75%	0.749	65%	0.651	S	S	*	*			trans	-118.1	9.9	-172.6	-109.7	138.2	0	0	0	112.4	Y404 T408	Y404-L406 WeakPolarHBondContact O-CB 3.21Å; Y404-L406 PolarHBondContact O-N 3.27Å; L406-T408 PolarHBondContact O-N 3.12Å; L406-T408 PolarHBondContact O-OG1 3.2Å
407	A	29.1	Very low	35.2	Very low	102 Å²	102	118 Å²	118	84%	0.843	66%	0.658	S	S	*	*			trans	-76.8	58.7	171.3	0	0	0	0	0	111.2
408	T	28.1	Very low	35.2	Very low	103 Å²	103	116.7 Å²	116.7	63%	0.632	66%	0.658	S	S	*	*	S	Bend	trans	-78.1	119.2	142.8	16.6	0	0	0	0	106.6	L406 V410	L406-T408 PolarHBondContact O-N 3.12Å; L406-T408 PolarHBondContact O-OG1 3.2Å; T408-V410 PolarHBondContact O-N 2.9Å; T408-V410 VanDerWaalsContact O-N 3.08Å
409	E	32.7	Very low	35.7	Very low	182 Å²	182	112 Å²	112	85%	0.85	64%	0.64	S	S	*	*	S	Bend	trans	70.2	-11.8	159	-66.3	-178.6	144.7	0	0	121.9
410	V	31.1	Very low	36.3	Very low	99 Å²	99	110.6 Å²	110.6	60%	0.6	64%	0.642	S	S	*	*	G	3₁₀ helix	trans	-86.6	-12.5	-169.5	-174.2	0	0	0	0	116.1	T408 V412 T413	T408-V410 PolarHBondContact O-N 2.9Å; T408-V410 VanDerWaalsContact O-N 3.08Å; V410-V412 PolarHBondContact O-N 3.09Å; V410-V412 VanDerWaalsContact O-N 3.11Å; V410-T413 PolarHBondContact O-N 3.29Å; V410-T413 VanDerWaalsContact O-N 3.13Å; V410-T413 PolarHBondContact O-OG1 2.92Å
411	D	32.2	Very low	37.3	Very low	132 Å²	132	110.8 Å²	110.8	71%	0.706	66%	0.658	S	S	*	*	G	3₁₀ helix	trans	-75.9	0.5	-176	-137.1	11.7	0	0	0	114.4
412	V	37.2	Very low	38.2	Very low	111 Å²	111	105.6 Å²	105.6	67%	0.673	63%	0.628	S	S	*	*	G	3₁₀ helix	trans	-93.7	-26.2	170.8	-177.1	0	0	0	0	111.5	V410	V410-V412 PolarHBondContact O-N 3.09Å; V410-V412 VanDerWaalsContact O-N 3.11Å
413	T	35.3	Very low	38.9	Very low	70 Å²	70	107.1 Å²	107.1	43%	0.429	62%	0.622	S	S	.	*	T	Hydrogen-bonded Turn	trans	-82	-32.2	-173.9	4.5	0	0	0	0	113.8	V410 S415 Q416 E417	V410-T413 PolarHBondContact O-N 3.29Å; V410-T413 VanDerWaalsContact O-N 3.13Å; V410-T413 PolarHBondContact O-OG1 2.92Å; T413-S415 VanDerWaalsContact C-N 3.29Å; T413-S415 PolarHBondContact O-N 3.42Å; T413-Q416 PolarHBondContact O-N 3.44Å; T413-Q416 VanDerWaalsContact O-N 3.1Å; T413-E417 PolarHBondContact O-N 3.36Å
414	S	38.2	Very low	39.9	Very low	60 Å²	60	102.6 Å²	102.6	42%	0.42	62%	0.621	S	S	.	*	H	α-helix	trans	-70.2	-24.8	178.6	63.7	0	0	0	0	113.4	Q416	S414-Q416 VanDerWaalsContact C-N 3.34Å
415	S	42.2	Very low	41.1	Very low	47 Å²	47	104.4 Å²	104.4	33%	0.329	64%	0.638	S	S	.	*	H	α-helix	trans	-78.8	-18.3	172.5	-63.8	0	0	0	0	112.7	T413 L419	T413-S415 VanDerWaalsContact C-N 3.29Å; T413-S415 PolarHBondContact O-N 3.42Å; S415-L419 WeakPolarHBondContact O-CD1 3.32Å; S415-L419 WeakPolarHBondContact O-CG 3.46Å
416	Q	39.9	Very low	42.1	Very low	129 Å²	129	105 Å²	105	60%	0.603	62%	0.615	S	S	*	*	H	α-helix	trans	-85.1	-33	176.9	-92	179.6	-39.1	0	0	112.7	T413 S414 L419	T413-Q416 PolarHBondContact O-N 3.44Å; T413-Q416 VanDerWaalsContact O-N 3.1Å; S414-Q416 VanDerWaalsContact C-N 3.34Å; Q416-L419 PolarHBondContact O-N 3.37Å
417	E	45.1	Very low	43.3	Very low	163 Å²	163	100.2 Å²	100.2	76%	0.762	59%	0.592	S	S	*	*	H	α-helix	trans	-74.9	-26.1	178.1	-68.4	-163.1	131.1	0	0	113.7	T413 L419	T413-E417 PolarHBondContact O-N 3.36Å; E417-L419 VanDerWaalsContact C-N 3.25Å; E417-L419 PolarHBondContact O-N 3.24Å
418	L	44.5	Very low	44.8	Very low	146 Å²	146	99.6 Å²	99.6	76%	0.764	58%	0.578	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.8	-12.7	173.9	-98.1	152.8	0	0	0	114
419	L	47.6	Very low	46.2	Very low	47 Å²	47	97.7 Å²	97.7	25%	0.246	57%	0.568	C	S	.	*	T	Hydrogen-bonded Turn	trans	-96.4	-2.5	179.3	-62.2	174.9	0	0	0	113.2	S415 Q416 E417 G421 S422 V427 F430	S415-L419 WeakPolarHBondContact O-CD1 3.32Å; S415-L419 WeakPolarHBondContact O-CG 3.46Å; Q416-L419 PolarHBondContact O-N 3.37Å; E417-L419 VanDerWaalsContact C-N 3.25Å; E417-L419 PolarHBondContact O-N 3.24Å; L419-G421 PolarHBondContact O-N 2.89Å; L419-S422 PolarHBondContact O-N 2.94Å; L419-V427 HydrophobicContact CB-CG2 4.39Å; L419-V427 HydrophobicContact CD1-CG1 4.35Å; L419-V427 HydrophobicContact CD2-CG2 4.08Å; L419-F430 HydrophobicContact CD1-CD1 4.21Å
420	V	51.1	Low	47.3	Very low	130 Å²	130	93 Å²	93	79%	0.788	55%	0.545	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.2	-4.4	-178.4	179.3	0	0	0	0	113.1
421	G	53.7	Low	48.6	Very low	81 Å²	81	93.6 Å²	93.6	84%	0.835	54%	0.542	S	S	*	.	T	Hydrogen-bonded Turn	trans	-134.7	15	173.8	0	0	0	0	0	114.8	L419	L419-G421 PolarHBondContact O-N 2.89Å
422	S	52.5	Low	50.1	Low	29 Å²	29	93.6 Å²	93.6	20%	0.203	54%	0.537	C	S	.	.			trans	-98.5	135.7	-169.8	-173.2	0	0	0	0	111.3	L419 E426	L419-S422 PolarHBondContact O-N 2.94Å; S422-E426 WeakPolarHBondContact OG-CB 3.41Å; S422-E426 PolarHBondContact OG-OE2 3.4Å
423	N	48.9	Very low	51.4	Low	129 Å²	129	93 Å²	93	69%	0.69	53%	0.527	S	S	*	.			trans	-57.4	144	178.4	-95.5	-25.6	0	0	0	109.8	N425 E426 V427	N423-N425 PolarHBondContact O-N 3.32Å; N423-E426 PolarHBondContact N-OE2 3.37Å; N423-E426 WeakPolarHBondContact O-CB 3.24Å; N423-E426 PolarHBondContact O-N 2.67Å; N423-V427 PolarHBondContact O-N 3.08Å
424	G	54.6	Low	53.1	Low	52 Å²	52	91.9 Å²	91.9	54%	0.536	52%	0.522	S	S	.	.	H	α-helix	trans	-51.4	-29.3	-176.5	0	0	0	0	0	114.6	V428	G424-V428 VanDerWaalsContact O-CG2 3.26Å; G424-V428 WeakPolarHBondContact O-CG2 3.08Å; G424-V428 PolarHBondContact O-N 3.39Å; G424-V428 VanDerWaalsContact O-N 3.13Å
425	N	58.3	Low	54.8	Low	143 Å²	143	95.6 Å²	95.6	77%	0.765	53%	0.531	S	S	*	.	H	α-helix	trans	-68.3	-33.1	174.9	-67	-9.1	0	0	0	113.9	N423 S429	N423-N425 PolarHBondContact O-N 3.32Å; N425-S429 WeakPolarHBondContact O-CB 3.19Å; N425-S429 PolarHBondContact O-N 2.94Å; N425-S429 PolarHBondContact O-OG 2.93Å
426	E	51.9	Low	56.4	Low	107 Å²	107	99.1 Å²	99.1	50%	0.5	54%	0.543	S	S	.	.	H	α-helix	trans	-76.6	-36.7	177.3	-73.9	-179.7	152.9	0	0	111.8	S422 N423 V428 S429 F430	S422-E426 WeakPolarHBondContact OG-CB 3.41Å; S422-E426 PolarHBondContact OG-OE2 3.4Å; N423-E426 PolarHBondContact N-OE2 3.37Å; N423-E426 WeakPolarHBondContact O-CB 3.24Å; N423-E426 PolarHBondContact O-N 2.67Å; E426-V428 VanDerWaalsContact C-N 3.33Å; E426-S429 WeakPolarHBondContact CA-OG 3.49Å; E426-S429 PolarHBondContact O-N 3.45Å; E426-S429 PolarHBondContact O-OG 2.89Å; E426-F430 VanDerWaalsContact O-CB 3.31Å; E426-F430 WeakPolarHBondContact O-CB 3.26Å; E426-F430 PolarHBondContact O-N 2.96Å
427	V	54.3	Low	58.2	Low	43 Å²	43	98.3 Å²	98.3	26%	0.261	54%	0.535	S	S	.	.	H	α-helix	trans	-62.1	-44.6	172.5	-178.9	0	0	0	0	110.2	L419 N423 F430 Q431	L419-V427 HydrophobicContact CB-CG2 4.39Å; L419-V427 HydrophobicContact CD1-CG1 4.35Å; L419-V427 HydrophobicContact CD2-CG2 4.08Å; N423-V427 PolarHBondContact O-N 3.08Å; V427-F430 PolarHBondContact O-N 2.94Å; V427-Q431 WeakPolarHBondContact O-CB 3.45Å; V427-Q431 WeakPolarHBondContact O-CG 3.35Å; V427-Q431 PolarHBondContact O-N 3.36Å
428	V	61.8	Low	59.7	Low	89 Å²	89	96.5 Å²	96.5	54%	0.539	53%	0.526	S	S	.	.	H	α-helix	trans	-64.6	-44	176.5	172.5	0	0	0	0	111.1	G424 E426 Q431 Q432	G424-V428 VanDerWaalsContact O-CG2 3.26Å; G424-V428 WeakPolarHBondContact O-CG2 3.08Å; G424-V428 PolarHBondContact O-N 3.39Å; G424-V428 VanDerWaalsContact O-N 3.13Å; E426-V428 VanDerWaalsContact C-N 3.33Å; V428-Q431 PolarHBondContact O-N 2.95Å; V428-Q432 WeakPolarHBondContact O-CB 3.47Å; V428-Q432 PolarHBondContact O-N 3.35Å
429	S	57.1	Low	61.4	Low	62 Å²	62	94.9 Å²	94.9	43%	0.434	52%	0.517	S	S	.	.	H	α-helix	trans	-65.6	-39.4	179	73.7	0	0	0	0	112.1	N425 E426 Q432 Q433	N425-S429 WeakPolarHBondContact O-CB 3.19Å; N425-S429 PolarHBondContact O-N 2.94Å; N425-S429 PolarHBondContact O-OG 2.93Å; E426-S429 WeakPolarHBondContact CA-OG 3.49Å; E426-S429 PolarHBondContact O-N 3.45Å; E426-S429 PolarHBondContact O-OG 2.89Å; S429-Q432 PolarHBondContact O-N 3.48Å; S429-Q433 VanDerWaalsContact O-CB 3.27Å; S429-Q433 WeakPolarHBondContact O-CB 3.34Å; S429-Q433 PolarHBondContact O-N 3.37Å
430	F	56.3	Low	63	Low	85 Å²	85	95.7 Å²	95.7	37%	0.373	52%	0.522	S	S	.	.	H	α-helix	trans	-66.4	-44.7	175.8	-174.8	-99.5	0	0	0	112	L419 E426 V427 Q432 Q433 S434	L419-F430 HydrophobicContact CD1-CD1 4.21Å; E426-F430 VanDerWaalsContact O-CB 3.31Å; E426-F430 WeakPolarHBondContact O-CB 3.26Å; E426-F430 PolarHBondContact O-N 2.96Å; V427-F430 PolarHBondContact O-N 2.94Å; F430-Q432 VanDerWaalsContact C-N 3.34Å; F430-Q432 PolarHBondContact O-N 2.94Å; F430-Q433 PolarHBondContact O-N 3.17Å; F430-S434 WeakPolarHBondContact O-CB 3.39Å; F430-S434 PolarHBondContact O-N 3.49Å
431	Q	57.8	Low	64.5	Low	111 Å²	111	94.1 Å²	94.1	52%	0.519	50%	0.501	S	S	.	.	H	α-helix	trans	-64	-39.4	174.4	-73.5	-143.5	-30.3	0	0	112.2	V427 V428 S434 K435	V427-Q431 WeakPolarHBondContact O-CB 3.45Å; V427-Q431 WeakPolarHBondContact O-CG 3.35Å; V427-Q431 PolarHBondContact O-N 3.36Å; V428-Q431 PolarHBondContact O-N 2.95Å; Q431-S434 PolarHBondContact O-N 2.91Å; Q431-K435 WeakPolarHBondContact O-CB 3.34Å; Q431-K435 WeakPolarHBondContact O-CG 3.32Å; Q431-K435 PolarHBondContact O-N 3.31Å
432	Q	63.6	Low	65.7	Low	131 Å²	131	92.1 Å²	92.1	61%	0.612	48%	0.48	S	S	*	.	H	α-helix	trans	-66.1	-40.6	175.9	-173.2	171.8	-15.6	0	0	111.2	V428 S429 F430 K435 M436	V428-Q432 WeakPolarHBondContact O-CB 3.47Å; V428-Q432 PolarHBondContact O-N 3.35Å; S429-Q432 PolarHBondContact O-N 3.48Å; F430-Q432 VanDerWaalsContact C-N 3.34Å; F430-Q432 PolarHBondContact O-N 2.94Å; Q432-K435 PolarHBondContact O-N 3.02Å; Q432-M436 WeakPolarHBondContact O-CB 3.4Å; Q432-M436 PolarHBondContact O-N 3.48Å
433	Q	65.6	Low	67.2	Low	99 Å²	99	94.6 Å²	94.6	46%	0.463	49%	0.494	S	S	.	.	H	α-helix	trans	-67	-39	176.3	-165.8	178.2	13.4	0	0	111.8	S429 F430 R437	S429-Q433 VanDerWaalsContact O-CB 3.27Å; S429-Q433 WeakPolarHBondContact O-CB 3.34Å; S429-Q433 PolarHBondContact O-N 3.37Å; F430-Q433 PolarHBondContact O-N 3.17Å; Q433-R437 WeakPolarHBondContact O-CB 3.36Å; Q433-R437 PolarHBondContact O-N 2.95Å
434	S	70.1	Confident	69.1	Low	47 Å²	47	93.9 Å²	93.9	33%	0.329	49%	0.485	S	S	.	.	H	α-helix	trans	-64.6	-51.5	173.6	179	0	0	0	0	111.4	F430 Q431 M436 R437 H438	F430-S434 WeakPolarHBondContact O-CB 3.39Å; F430-S434 PolarHBondContact O-N 3.49Å; Q431-S434 PolarHBondContact O-N 2.91Å; S434-M436 PolarHBondContact O-N 3.38Å; S434-R437 WeakPolarHBondContact O-CB 3.29Å; S434-R437 PolarHBondContact O-N 2.92Å; S434-R437 VanDerWaalsContact O-N 3.17Å; S434-H438 PolarHBondContact O-CD2 3.04Å; S434-H438 PolarHBondContact O-N 3.46Å; S434-H438 PolarHBondContact OG-CD2 3.38Å
435	K	73.6	Confident	70.7	Confident	137 Å²	137	92 Å²	92	60%	0.596	46%	0.462	S	S	*	.	H	α-helix	trans	-57.6	-46.3	175.7	-76.2	-179.9	-178.2	177.3	0	112	Q431 Q432 R437 H438 I439	Q431-K435 WeakPolarHBondContact O-CB 3.34Å; Q431-K435 WeakPolarHBondContact O-CG 3.32Å; Q431-K435 PolarHBondContact O-N 3.31Å; Q432-K435 PolarHBondContact O-N 3.02Å; K435-R437 VanDerWaalsContact C-N 3.34Å; K435-R437 PolarHBondContact O-N 3.4Å; K435-H438 PolarHBondContact O-N 3.46Å; K435-I439 WeakPolarHBondContact O-CG1 3.37Å; K435-I439 PolarHBondContact O-N 3.27Å
436	M	75.8	Confident	72.2	Confident	121 Å²	121	85.1 Å²	85.1	60%	0.596	43%	0.426	S	S	*	.	H	α-helix	trans	-61.2	-43.2	177.2	-176.7	170.4	65	0	0	111.2	Q432 S434 H438 I439 L440	Q432-M436 WeakPolarHBondContact O-CB 3.4Å; Q432-M436 PolarHBondContact O-N 3.48Å; S434-M436 PolarHBondContact O-N 3.38Å; M436-H438 PolarHBondContact O-N 2.96Å; M436-I439 PolarHBondContact O-N 2.83Å; M436-L440 WeakPolarHBondContact O-CB 3.47Å; M436-L440 PolarHBondContact O-N 3.4Å
437	R	77.4	Confident	74.1	Confident	113 Å²	113	84 Å²	84	43%	0.426	42%	0.423	S	S	.	.	H	α-helix	trans	-63.4	-40.2	175.2	-169.3	-176.8	-60.7	-177.4	2.5	111.7	F391 Q433 S434 K435 L440 R441	F391-R437 HydrophobicContact CD1-CG 4.28Å; F391-R437 HydrophobicContact CE1-CG 4.42Å; Q433-R437 WeakPolarHBondContact O-CB 3.36Å; Q433-R437 PolarHBondContact O-N 2.95Å; S434-R437 WeakPolarHBondContact O-CB 3.29Å; S434-R437 PolarHBondContact O-N 2.92Å; S434-R437 VanDerWaalsContact O-N 3.17Å; K435-R437 VanDerWaalsContact C-N 3.34Å; K435-R437 PolarHBondContact O-N 3.4Å; R437-L440 PolarHBondContact O-N 3.25Å; R437-R441 HydrophobicContact CG-CG 4.39Å; R437-R441 VanDerWaalsContact O-CB 3.28Å; R437-R441 WeakPolarHBondContact O-CB 3.48Å; R437-R441 WeakPolarHBondContact O-CG 3.43Å; R437-R441 PolarHBondContact O-N 2.97Å
438	H	77.3	Confident	75.9	Confident	124 Å²	124	85.2 Å²	85.2	57%	0.574	43%	0.428	S	S	*	.	H	α-helix	trans	-65	-43.3	175.1	-78.5	-68.8	0	0	0	112.5	S434 K435 M436 G442	S434-H438 PolarHBondContact O-CD2 3.04Å; S434-H438 PolarHBondContact O-N 3.46Å; S434-H438 PolarHBondContact OG-CD2 3.38Å; K435-H438 PolarHBondContact O-N 3.46Å; M436-H438 PolarHBondContact O-N 2.96Å; H438-G442 WeakPolarHBondContact O-CA 3.3Å; H438-G442 PolarHBondContact O-N 3.41Å
439	I	80	Confident	77.4	Confident	112 Å²	112	81 Å²	81	57%	0.574	40%	0.402	S	S	*	.	H	α-helix	trans	-65.4	-44.3	175.9	-67.8	167.4	0	0	0	110.6	K435 M436 R441 G442 V443 F444	K435-I439 WeakPolarHBondContact O-CG1 3.37Å; K435-I439 PolarHBondContact O-N 3.27Å; M436-I439 PolarHBondContact O-N 2.83Å; I439-R441 PolarHBondContact O-N 3.33Å; I439-G442 PolarHBondContact O-N 3.29Å; I439-V443 WeakPolarHBondContact O-CB 3.28Å; I439-V443 PolarHBondContact O-N 3.4Å; I439-F444 PolarHBondContact O-N 2.93Å
440	L	82	Confident	79.2	Confident	65 Å²	65	78.6 Å²	78.6	34%	0.34	39%	0.385	S	S	.	.	I	π-helix	trans	-61.5	-46	179.2	-171.5	68.6	0	0	0	111.2	F391 M436 R437 F444 L445	F391-L440 HydrophobicContact CE1-CD2 3.73Å; F391-L440 HydrophobicContact CZ-CD2 3.5Å; F391-L440 HydrophobicContact CZ-CG 3.99Å; M436-L440 WeakPolarHBondContact O-CB 3.47Å; M436-L440 PolarHBondContact O-N 3.4Å; R437-L440 PolarHBondContact O-N 3.25Å; L440-F444 HydrophobicContact CD1-CB 3.93Å; L440-F444 HydrophobicContact CD1-CD1 3.47Å; L440-F444 VanDerWaalsContact CD1-CD1 3.47Å; L440-F444 HydrophobicContact CD1-CE1 4.19Å; L440-F444 HydrophobicContact CD1-CG 3.84Å; L440-F444 PolarHBondContact O-N 3.26Å; L440-L445 WeakPolarHBondContact O-CB 3.47Å; L440-L445 PolarHBondContact O-N 2.84Å
441	R	82.1	Confident	81	Confident	97 Å²	97	77.4 Å²	77.4	37%	0.366	38%	0.384	S	S	.	.	I	π-helix	trans	-74.3	-36	178.9	-68	172.5	75.8	-176.3	7.6	113.2	D387 F391 R437 I439 P446	D387-R441 IonicContact OD1-CZ 2.7Å; D387-R441 IonicContact OD1-NE 2.72Å; D387-R441 PolarHBondContact OD1-NE 3.2Å; D387-R441 IonicContact OD1-NH2 3.04Å; D387-R441 PolarHBondContact OD1-NH2 2.93Å; D387-R441 IonicContact OD2-CZ 3.99Å; D387-R441 IonicContact OD2-NE 3.35Å; D387-R441 IonicContact OD2-NH2 2.83Å; D387-R441 PolarHBondContact OD2-NH2 3.21Å; F391-R441 HydrophobicContact CD2-CG 3.96Å; F391-R441 HydrophobicContact CE1-CG 4.48Å; F391-R441 HydrophobicContact CE2-CG 3.8Å; F391-R441 HydrophobicContact CG-CG 4.37Å; F391-R441 HydrophobicContact CZ-CG 4.09Å; R437-R441 HydrophobicContact CG-CG 4.39Å; R437-R441 VanDerWaalsContact O-CB 3.28Å; R437-R441 WeakPolarHBondContact O-CB 3.48Å; R437-R441 WeakPolarHBondContact O-CG 3.43Å; R437-R441 PolarHBondContact O-N 2.97Å; I439-R441 PolarHBondContact O-N 3.33Å; R441-P446 WeakPolarHBondContact O-CD 3.3Å
442	G	78.8	Confident	82.8	Confident	38 Å²	38	75 Å²	75	39%	0.392	38%	0.377	S	S	.	.	I	π-helix	trans	-88.6	-26.4	-172.5	0	0	0	0	0	115	H438 I439 P446	H438-G442 WeakPolarHBondContact O-CA 3.3Å; H438-G442 PolarHBondContact O-N 3.41Å; I439-G442 PolarHBondContact O-N 3.29Å; G442-P446 WeakPolarHBondContact O-CG 3.12Å
443	V	84.6	Confident	84.3	Confident	82 Å²	82	68.8 Å²	68.8	50%	0.497	35%	0.348	S	S	.	.	I	π-helix	trans	-124.1	-57.7	-174.9	-177.3	0	0	0	0	111.5	I439 L445 P446 L447	I439-V443 WeakPolarHBondContact O-CB 3.28Å; I439-V443 PolarHBondContact O-N 3.4Å; V443-L445 PolarHBondContact O-N 3.4Å; V443-P446 WeakPolarHBondContact O-CD 3.27Å; V443-L447 VanDerWaalsContact O-CB 3.29Å; V443-L447 WeakPolarHBondContact O-CB 3.47Å; V443-L447 PolarHBondContact O-N 3.28Å; V443-L447 VanDerWaalsContact O-N 3.08Å
444	F	88.4	Confident	85.7	Confident	114 Å²	114	65 Å²	65	50%	0.5	33%	0.331	S	S	.	.	I	π-helix	trans	-65.9	-44	-173.2	-179.7	-96.4	0	0	0	112.2	I439 L440 L447 L448	I439-F444 PolarHBondContact O-N 2.93Å; L440-F444 HydrophobicContact CD1-CB 3.93Å; L440-F444 HydrophobicContact CD1-CD1 3.47Å; L440-F444 VanDerWaalsContact CD1-CD1 3.47Å; L440-F444 HydrophobicContact CD1-CE1 4.19Å; L440-F444 HydrophobicContact CD1-CG 3.84Å; L440-F444 PolarHBondContact O-N 3.26Å; F444-L447 WeakPolarHBondContact O-CB 3.37Å; F444-L447 PolarHBondContact O-N 3.05Å; F444-L448 HydrophobicContact CE1-CD1 3.9Å; F444-L448 HydrophobicContact CZ-CD1 4.14Å; F444-L448 WeakPolarHBondContact O-CB 3.16Å; F444-L448 PolarHBondContact O-N 2.98Å
445	L	89	Confident	87	Confident	11 Å²	11	65.6 Å²	65.6	6%	0.058	34%	0.335	C	S	.	.	H	α-helix	trans	-65.2	-50.4	-178.6	178.7	64.2	0	0	0	112.9	R383 I386 D387 L440 V443 L447 L448 V449	R383-L445 HydrophobicContact CG-CD2 3.71Å; R383-L445 HydrophobicContact CG-CG 3.93Å; I386-L445 HydrophobicContact CB-CD1 3.82Å; I386-L445 HydrophobicContact CD1-CD1 3.97Å; I386-L445 HydrophobicContact CG2-CD1 3.33Å; I386-L445 HydrophobicContact CG2-CD2 4.41Å; I386-L445 HydrophobicContact CG2-CG 4.5Å; D387-L445 HydrophobicContact CB-CD2 4.15Å; L440-L445 WeakPolarHBondContact O-CB 3.47Å; L440-L445 PolarHBondContact O-N 2.84Å; V443-L445 PolarHBondContact O-N 3.4Å; L445-L447 VanDerWaalsContact C-N 3.27Å; L445-L447 PolarHBondContact O-N 3.44Å; L445-L448 PolarHBondContact O-N 3.29Å; L445-V449 HydrophobicContact CD1-CG2 4.31Å; L445-V449 WeakPolarHBondContact O-CB 3.31Å; L445-V449 VanDerWaalsContact O-CG2 3.26Å; L445-V449 WeakPolarHBondContact O-CG2 3.5Å; L445-V449 PolarHBondContact O-N 2.99Å
446	P	89.2	Confident	88.1	Confident	0 Å²	0	61.3 Å²	61.3	0%	0	32%	0.32	C	S	.	.	H	α-helix	trans	-57.9	-38.4	171.9	-17.3	22.2	0	0	0	113.1	V225 F226 R441 G442 V443 V449 V450	V225-P446 HydrophobicContact CG1-CB 4.4Å; F226-P446 HydrophobicContact CD1-CB 3.72Å; F226-P446 HydrophobicContact CD1-CG 4.07Å; F226-P446 HydrophobicContact CD2-CB 4.18Å; F226-P446 HydrophobicContact CE1-CB 3.74Å; F226-P446 HydrophobicContact CE1-CG 4.29Å; F226-P446 HydrophobicContact CE2-CB 4.19Å; F226-P446 HydrophobicContact CG-CB 3.95Å; F226-P446 HydrophobicContact CZ-CB 3.98Å; R441-P446 WeakPolarHBondContact O-CD 3.3Å; G442-P446 WeakPolarHBondContact O-CG 3.12Å; V443-P446 WeakPolarHBondContact O-CD 3.27Å; P446-V449 PolarHBondContact O-N 2.92Å; P446-V450 WeakPolarHBondContact O-CG2 3.28Å; P446-V450 PolarHBondContact O-N 3.01Å; P446-V450 VanDerWaalsContact O-N 3.1Å
447	L	91.9	Very high	89	Confident	84 Å²	84	55.5 Å²	55.5	44%	0.44	29%	0.292	S	S	.	.	H	α-helix	trans	-60.5	-50.8	176.9	-177.1	68.6	0	0	0	110.6	F226 V443 F444 L445 V449 V450 T451	F226-L447 HydrophobicContact CZ-CB 4.17Å; F226-L447 HydrophobicContact CZ-CD1 4.45Å; V443-L447 VanDerWaalsContact O-CB 3.29Å; V443-L447 WeakPolarHBondContact O-CB 3.47Å; V443-L447 PolarHBondContact O-N 3.28Å; V443-L447 VanDerWaalsContact O-N 3.08Å; F444-L447 WeakPolarHBondContact O-CB 3.37Å; F444-L447 PolarHBondContact O-N 3.05Å; L445-L447 VanDerWaalsContact C-N 3.27Å; L445-L447 PolarHBondContact O-N 3.44Å; L447-V449 VanDerWaalsContact C-N 3.32Å; L447-V449 PolarHBondContact O-N 2.79Å; L447-V450 PolarHBondContact O-N 3.12Å; L447-V450 VanDerWaalsContact O-N 3.14Å; L447-T451 HydrophobicContact CD1-CG2 3.7Å; L447-T451 HydrophobicContact CG-CG2 4.04Å; L447-T451 WeakPolarHBondContact O-CB 3.46Å; L447-T451 WeakPolarHBondContact O-CG2 3.5Å; L447-T451 PolarHBondContact O-N 3.12Å; L447-T451 PolarHBondContact O-OG1 2.67Å
448	L	92.4	Very high	89.9	Confident	67 Å²	67	53.4 Å²	53.4	35%	0.351	29%	0.286	S	S	.	.	H	α-helix	trans	-59	-42.5	177.6	-176.5	147.4	0	0	0	112	F444 L445 V450 V452	F444-L448 HydrophobicContact CE1-CD1 3.9Å; F444-L448 HydrophobicContact CZ-CD1 4.14Å; F444-L448 WeakPolarHBondContact O-CB 3.16Å; F444-L448 PolarHBondContact O-N 2.98Å; L445-L448 PolarHBondContact O-N 3.29Å; L448-V450 PolarHBondContact O-N 3.13Å; L448-V452 HydrophobicContact CD2-CG2 4.33Å; L448-V452 HydrophobicContact CG-CG2 3.9Å; L448-V452 WeakPolarHBondContact O-CB 3.12Å; L448-V452 VanDerWaalsContact O-CG2 3.29Å; L448-V452 WeakPolarHBondContact O-CG2 3.5Å; L448-V452 PolarHBondContact O-N 3.45Å; L448-V452 VanDerWaalsContact O-N 3.12Å
449	V	93.2	Very high	90.7	Very high	2 Å²	2	54.7 Å²	54.7	1%	0.012	29%	0.29	C	S	.	.	H	α-helix	trans	-60.9	-31.5	177.6	161.8	0	0	0	0	112.6	L156 V225 G379 L382 R383 I386 L445 P446 L447 P453	L156-V449 HydrophobicContact CD1-CG1 4.1Å; V225-V449 HydrophobicContact CG1-CG1 4.03Å; G379-V449 WeakPolarHBondContact O-CG1 3.38Å; L382-V449 HydrophobicContact CB-CG1 4.32Å; L382-V449 HydrophobicContact CD2-CG1 4.11Å; L382-V449 HydrophobicContact CD2-CG2 4.26Å; L382-V449 HydrophobicContact CG-CG1 4.33Å; L382-V449 HydrophobicContact CG-CG2 4.06Å; R383-V449 HydrophobicContact CB-CG2 4.22Å; I386-V449 HydrophobicContact CD1-CG2 3.72Å; L445-V449 HydrophobicContact CD1-CG2 4.31Å; L445-V449 WeakPolarHBondContact O-CB 3.31Å; L445-V449 VanDerWaalsContact O-CG2 3.26Å; L445-V449 WeakPolarHBondContact O-CG2 3.5Å; L445-V449 PolarHBondContact O-N 2.99Å; P446-V449 PolarHBondContact O-N 2.92Å; L447-V449 VanDerWaalsContact C-N 3.32Å; L447-V449 PolarHBondContact O-N 2.79Å; V449-P453 WeakPolarHBondContact O-CD 3.4Å; V449-P453 WeakPolarHBondContact O-CG 3.43Å
450	V	93.7	Very high	91.4	Very high	11 Å²	11	51.3 Å²	51.3	7%	0.067	28%	0.275	C	S	.	.	H	α-helix	trans	-89.8	-46.8	178.6	172.7	0	0	0	0	111.2	V225 P446 L447 L448 L454	V225-V450 HydrophobicContact CB-CG2 3.92Å; V225-V450 HydrophobicContact CG1-CG2 4.22Å; V225-V450 HydrophobicContact CG2-CG2 3.81Å; P446-V450 WeakPolarHBondContact O-CG2 3.28Å; P446-V450 PolarHBondContact O-N 3.01Å; P446-V450 VanDerWaalsContact O-N 3.1Å; L447-V450 PolarHBondContact O-N 3.12Å; L447-V450 VanDerWaalsContact O-N 3.14Å; L448-V450 PolarHBondContact O-N 3.13Å; V450-L454 HydrophobicContact CG1-CD1 3.62Å; V450-L454 WeakPolarHBondContact O-CB 2.99Å; V450-L454 WeakPolarHBondContact O-CD1 3.14Å; V450-L454 WeakPolarHBondContact O-CG 3.36Å; V450-L454 PolarHBondContact O-N 3.15Å
451	T	93.8	Very high	91.8	Very high	59 Å²	59	49.2 Å²	49.2	36%	0.362	26%	0.264	S	S	.	.	H	α-helix	trans	-73.3	-37.8	-170.8	57	0	0	0	0	113.1	L447 S455	L447-T451 HydrophobicContact CD1-CG2 3.7Å; L447-T451 HydrophobicContact CG-CG2 4.04Å; L447-T451 WeakPolarHBondContact O-CB 3.46Å; L447-T451 WeakPolarHBondContact O-CG2 3.5Å; L447-T451 PolarHBondContact O-N 3.12Å; L447-T451 PolarHBondContact O-OG1 2.67Å; T451-S455 WeakPolarHBondContact O-CB 3.13Å; T451-S455 PolarHBondContact O-N 3.18Å; T451-S455 PolarHBondContact O-OG 3.25Å
452	V	95.5	Very high	92.3	Very high	61 Å²	61	47.5 Å²	47.5	37%	0.37	26%	0.262	S	S	.	.	H	α-helix	trans	-67.8	-49.2	-177	-172.9	0	0	0	0	111.2	F153 L448 L454 S455 V456	F153-V452 HydrophobicContact CD2-CG1 4.48Å; F153-V452 HydrophobicContact CE2-CB 3.86Å; F153-V452 HydrophobicContact CE2-CG1 3.42Å; F153-V452 VanDerWaalsContact CE2-CG1 3.42Å; F153-V452 HydrophobicContact CZ-CG1 3.87Å; L448-V452 HydrophobicContact CD2-CG2 4.33Å; L448-V452 HydrophobicContact CG-CG2 3.9Å; L448-V452 WeakPolarHBondContact O-CB 3.12Å; L448-V452 VanDerWaalsContact O-CG2 3.29Å; L448-V452 WeakPolarHBondContact O-CG2 3.5Å; L448-V452 PolarHBondContact O-N 3.45Å; L448-V452 VanDerWaalsContact O-N 3.12Å; V452-L454 VanDerWaalsContact C-N 3.34Å; V452-L454 PolarHBondContact O-N 2.82Å; V452-S455 WeakPolarHBondContact O-CB 3.18Å; V452-S455 PolarHBondContact O-N 2.98Å; V452-S455 VanDerWaalsContact O-N 3.17Å; V452-V456 PolarHBondContact O-N 2.74Å
453	P	96.1	Very high	93	Very high	1 Å²	1	45.8 Å²	45.8	1%	0.006	24%	0.244	C	C	.	.	H	α-helix	trans	-63.1	-38.7	176.4	-20.1	30.3	0	0	0	113.3	F153 L156 A157 V449 S455 V456 A457	F153-P453 HydrophobicContact CD2-CB 4.36Å; F153-P453 HydrophobicContact CD2-CG 3.63Å; F153-P453 HydrophobicContact CE2-CB 4.1Å; F153-P453 HydrophobicContact CE2-CG 3.64Å; L156-P453 HydrophobicContact CB-CB 3.6Å; L156-P453 HydrophobicContact CB-CG 3.73Å; L156-P453 HydrophobicContact CD1-CG 4.1Å; A157-P453 HydrophobicContact CB-CB 4.17Å; V449-P453 WeakPolarHBondContact O-CD 3.4Å; V449-P453 WeakPolarHBondContact O-CG 3.43Å; P453-S455 VanDerWaalsContact C-N 3.28Å; P453-S455 PolarHBondContact O-N 2.91Å; P453-V456 WeakPolarHBondContact O-CB 3.37Å; P453-V456 PolarHBondContact O-N 3.39Å; P453-A457 PolarHBondContact O-N 2.93Å; P453-A457 VanDerWaalsContact O-N 3.07Å
454	L	95.9	Very high	93.3	Very high	19 Å²	19	42.1 Å²	42.1	10%	0.099	22%	0.222	C	C	.	.	H	α-helix	trans	-68.2	-29	176.2	-68.7	176.2	0	0	0	112.6	V214 F217 V450 V452 V456 A457 F458	V214-L454 HydrophobicContact CG1-CB 4.48Å; V214-L454 HydrophobicContact CG1-CD2 4.2Å; F217-L454 HydrophobicContact CD1-CD2 3.75Å; F217-L454 HydrophobicContact CE1-CD2 4.04Å; V450-L454 HydrophobicContact CG1-CD1 3.62Å; V450-L454 WeakPolarHBondContact O-CB 2.99Å; V450-L454 WeakPolarHBondContact O-CD1 3.14Å; V450-L454 WeakPolarHBondContact O-CG 3.36Å; V450-L454 PolarHBondContact O-N 3.15Å; V452-L454 VanDerWaalsContact C-N 3.34Å; V452-L454 PolarHBondContact O-N 2.82Å; L454-V456 VanDerWaalsContact C-N 3.33Å; L454-A457 CarbonylContact O-C 3.48Å; L454-A457 PolarHBondContact O-N 3.04Å; L454-F458 WeakPolarHBondContact O-CB 3.09Å; L454-F458 PolarHBondContact O-N 3.39Å
455	S	96.4	Very high	93.4	Very high	59 Å²	59	39.5 Å²	39.5	41%	0.413	21%	0.214	S	C	.	.	H	α-helix	trans	-64.4	-42.1	173.1	-59.6	0	0	0	0	110.3	T451 V452 P453 F458 F459	T451-S455 WeakPolarHBondContact O-CB 3.13Å; T451-S455 PolarHBondContact O-N 3.18Å; T451-S455 PolarHBondContact O-OG 3.25Å; V452-S455 WeakPolarHBondContact O-CB 3.18Å; V452-S455 PolarHBondContact O-N 2.98Å; V452-S455 VanDerWaalsContact O-N 3.17Å; P453-S455 VanDerWaalsContact C-N 3.28Å; P453-S455 PolarHBondContact O-N 2.91Å; S455-F458 WeakPolarHBondContact O-CB 3.32Å; S455-F458 PolarHBondContact O-N 2.86Å; S455-F459 WeakPolarHBondContact O-CD2 3.33Å; S455-F459 PolarHBondContact O-N 2.74Å
456	V	96.2	Very high	93.6	Very high	47 Å²	47	39.9 Å²	39.9	29%	0.285	22%	0.217	S	C	.	.	H	α-helix	trans	-58.9	-51.6	172.7	176.3	0	0	0	0	110.3	F153 A157 V452 P453 L454 F458 F459 T460 L466	F153-V456 HydrophobicContact CE1-CG2 4.34Å; F153-V456 HydrophobicContact CZ-CG2 3.81Å; A157-V456 HydrophobicContact CB-CB 4.26Å; A157-V456 HydrophobicContact CB-CG1 4.22Å; V452-V456 PolarHBondContact O-N 2.74Å; P453-V456 WeakPolarHBondContact O-CB 3.37Å; P453-V456 PolarHBondContact O-N 3.39Å; L454-V456 VanDerWaalsContact C-N 3.33Å; V456-F458 PolarHBondContact O-N 3.48Å; V456-F459 PolarHBondContact O-N 3.33Å; V456-T460 HydrophobicContact CG1-CG2 4.03Å; V456-T460 WeakPolarHBondContact O-CG2 3.36Å; V456-T460 PolarHBondContact O-N 2.87Å; V456-L466 HydrophobicContact CG1-CD2 3.52Å
457	A	95.4	Very high	93.9	Very high	0 Å²	0	40 Å²	40	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-60.9	-27.2	177.2	0	0	0	0	0	113.3	G160 A161 Y210 V214 P453 L454 F459 T460	G160-A457 VanDerWaalsContact C-CB 3.45Å; G160-A457 WeakPolarHBondContact O-CB 3.43Å; A161-A457 HydrophobicContact CB-CB 4.27Å; Y210-A457 WeakPolarHBondContact CE1-O 3.33Å; Y210-A457 VanDerWaalsContact CZ-O 3.23Å; Y210-A457 PolarHBondContact OH-O 3.01Å; V214-A457 HydrophobicContact CG1-CB 4.31Å; P453-A457 PolarHBondContact O-N 2.93Å; P453-A457 VanDerWaalsContact O-N 3.07Å; L454-A457 CarbonylContact O-C 3.48Å; L454-A457 PolarHBondContact O-N 3.04Å; A457-F459 VanDerWaalsContact C-N 3.3Å; A457-F459 PolarHBondContact O-N 3.29Å; A457-T460 CarbonylContact C-O 3.57Å
458	F	95.6	Very high	93.9	Very high	69 Å²	69	36 Å²	36	30%	0.303	20%	0.196	S	C	.	.	H	α-helix	trans	-70	-27.3	177.1	-168.3	-91.2	0	0	0	113.1	R211 V214 L454 S455 V456	R211-F458 HydrophobicContact CB-CD2 4.06Å; R211-F458 HydrophobicContact CB-CE2 3.61Å; R211-F458 HydrophobicContact CB-CZ 4.02Å; R211-F458 HydrophobicContact CG-CD1 4.41Å; R211-F458 HydrophobicContact CG-CD2 3.96Å; R211-F458 HydrophobicContact CG-CE1 4.26Å; R211-F458 HydrophobicContact CG-CE2 3.81Å; R211-F458 HydrophobicContact CG-CG 4.27Å; R211-F458 HydrophobicContact CG-CZ 3.96Å; R211-F458 PolarHBondContact NE-O 3.43Å; V214-F458 HydrophobicContact CG1-CB 4.5Å; L454-F458 WeakPolarHBondContact O-CB 3.09Å; L454-F458 PolarHBondContact O-N 3.39Å; S455-F458 WeakPolarHBondContact O-CB 3.32Å; S455-F458 PolarHBondContact O-N 2.86Å; V456-F458 PolarHBondContact O-N 3.48Å
459	F	95.2	Very high	93.9	Very high	150 Å²	150	34.4 Å²	34.4	66%	0.658	19%	0.193	S	C	*	.	H	α-helix	trans	-99.4	-22.6	-178.1	-69	-66.9	0	0	0	114.1	S455 V456 A457	S455-F459 WeakPolarHBondContact O-CD2 3.33Å; S455-F459 PolarHBondContact O-N 2.74Å; V456-F459 PolarHBondContact O-N 3.33Å; A457-F459 VanDerWaalsContact C-N 3.3Å; A457-F459 PolarHBondContact O-N 3.29Å
460	T	93.4	Very high	94	Very high	41 Å²	41	35 Å²	35	25%	0.252	20%	0.197	S	C	.	.			trans	-134.6	138.5	176.4	-178.8	0	0	0	0	111.2	Y210 V456 A457 D462 L466	Y210-T460 PolarHBondContact OH-O 3.37Å; V456-T460 HydrophobicContact CG1-CG2 4.03Å; V456-T460 WeakPolarHBondContact O-CG2 3.36Å; V456-T460 PolarHBondContact O-N 2.87Å; A457-T460 CarbonylContact C-O 3.57Å; T460-D462 PolarHBondContact OG1-N 3.45Å; T460-D462 VanDerWaalsContact OG1-N 3.12Å; T460-L466 HydrophobicContact CG2-CD1 4.19Å; T460-L466 HydrophobicContact CG2-CD2 4.04Å; T460-L466 HydrophobicContact CG2-CG 4.23Å
461	D	91.6	Very high	94	Very high	22 Å²	22	34.5 Å²	34.5	12%	0.118	19%	0.193	C	C	.	.			trans	-108.7	5.5	168.9	76.6	-58.2	0	0	0	112	K165 F207 Y210 V463	K165-D461 HydrophobicContact CD-CB 4.39Å; K165-D461 WeakPolarHBondContact CD-O 3.28Å; K165-D461 WeakPolarHBondContact CE-OD2 3.41Å; K165-D461 PolarHBondContact NZ-O 3.29Å; K165-D461 IonicContact NZ-OD2 3.88Å; K165-D461 PolarHBondContact NZ-OD2 3.44Å; F207-D461 HydrophobicContact CE2-CB 4.32Å; Y210-D461 HydrophobicContact CD1-CB 4.33Å; Y210-D461 HydrophobicContact CD2-CB 4.42Å; Y210-D461 HydrophobicContact CE1-CB 3.84Å; Y210-D461 HydrophobicContact CE2-CB 3.94Å; D461-V463 PolarHBondContact O-N 2.87Å; D461-V463 VanDerWaalsContact O-N 3.13Å
462	D	91.6	Very high	94	Very high	60 Å²	60	31.7 Å²	31.7	32%	0.321	18%	0.176	S	C	.	.			trans	-76.9	97.5	177.3	-169.7	-33.6	0	0	0	110.1	T460 E464 V465 L466	T460-D462 PolarHBondContact OG1-N 3.45Å; T460-D462 VanDerWaalsContact OG1-N 3.12Å; D462-E464 VanDerWaalsContact C-N 3.35Å; D462-E464 PolarHBondContact OD1-N 2.85Å; D462-E464 VanDerWaalsContact OD1-N 3.13Å; D462-V465 HydrophobicContact CB-CB 4.32Å; D462-V465 HydrophobicContact CB-CG2 4.41Å; D462-V465 VanDerWaalsContact CG-CG2 3.47Å; D462-V465 WeakPolarHBondContact OD1-CG2 3.48Å; D462-V465 PolarHBondContact OD1-N 2.9Å; D462-V465 VanDerWaalsContact OD2-CG2 3.29Å; D462-V465 WeakPolarHBondContact OD2-CG2 3.48Å; D462-L466 WeakPolarHBondContact O-CG 3.32Å; D462-L466 PolarHBondContact O-N 3.19Å
463	V	93.4	Very high	93.8	Very high	2 Å²	2	33.2 Å²	33.2	1%	0.012	18%	0.176	C	C	.	.	H	α-helix	trans	-72.6	-32.4	-176.8	173.4	0	0	0	0	111.2	I158 A161 V162 K165 D336 V337 D461 L466 I467	I158-V463 HydrophobicContact CG2-CG1 4.37Å; A161-V463 HydrophobicContact CB-CG2 4.13Å; V162-V463 HydrophobicContact CG2-CB 4.22Å; V162-V463 HydrophobicContact CG2-CG1 3.45Å; V162-V463 VanDerWaalsContact CG2-CG1 3.45Å; V162-V463 HydrophobicContact CG2-CG2 3.65Å; K165-V463 HydrophobicContact CD-CG2 4.33Å; D336-V463 HydrophobicContact CB-CB 4.34Å; D336-V463 PolarHBondContact OD2-N 3.45Å; V337-V463 HydrophobicContact CG2-CB 3.95Å; V337-V463 HydrophobicContact CG2-CG1 4.07Å; V337-V463 HydrophobicContact CG2-CG2 3.68Å; D461-V463 PolarHBondContact O-N 2.87Å; D461-V463 VanDerWaalsContact O-N 3.13Å; V463-L466 PolarHBondContact O-N 3.32Å; V463-I467 HydrophobicContact CG1-CD1 3.6Å; V463-I467 HydrophobicContact CG1-CG1 4.24Å; V463-I467 WeakPolarHBondContact O-CB 3.29Å; V463-I467 WeakPolarHBondContact O-CG1 3.06Å; V463-I467 PolarHBondContact O-N 3.27Å
464	E	91.9	Very high	93.8	Very high	6 Å²	6	33.3 Å²	33.3	3%	0.028	18%	0.177	C	C	.	.	H	α-helix	trans	-65.4	-46.8	-179.2	178.7	175.7	-158.6	0	0	110.7	R30 A31 N277 D336 D462 L466 I467 S468	R30-E464 VanDerWaalsContact CG-CD 3.47Å; R30-E464 HydrophobicContact CG-CG 4.44Å; R30-E464 WeakPolarHBondContact CG-OE2 3.42Å; R30-E464 IonicContact NE-OE2 3.52Å; R30-E464 PolarHBondContact NE-OE2 3.46Å; A31-E464 WeakPolarHBondContact CA-OE1 3.5Å; N277-E464 HydrophobicContact CB-CG 4.15Å; N277-E464 WeakPolarHBondContact CB-OE1 3.38Å; D336-E464 HydrophobicContact CB-CB 4.1Å; D462-E464 VanDerWaalsContact C-N 3.35Å; D462-E464 PolarHBondContact OD1-N 2.85Å; D462-E464 VanDerWaalsContact OD1-N 3.13Å; E464-L466 PolarHBondContact O-N 2.89Å; E464-I467 PolarHBondContact O-N 3.23Å; E464-S468 WeakPolarHBondContact O-CB 2.99Å; E464-S468 PolarHBondContact O-N 2.98Å
465	V	89.8	Confident	93.7	Very high	58 Å²	58	32.4 Å²	32.4	35%	0.352	17%	0.172	S	C	.	.	H	α-helix	trans	-62.7	-42.8	177.2	171.9	0	0	0	0	111.1	D462 S468 A469	D462-V465 HydrophobicContact CB-CB 4.32Å; D462-V465 HydrophobicContact CB-CG2 4.41Å; D462-V465 VanDerWaalsContact CG-CG2 3.47Å; D462-V465 WeakPolarHBondContact OD1-CG2 3.48Å; D462-V465 PolarHBondContact OD1-N 2.9Å; D462-V465 VanDerWaalsContact OD2-CG2 3.29Å; D462-V465 WeakPolarHBondContact OD2-CG2 3.48Å; V465-S468 PolarHBondContact O-N 3.13Å; V465-A469 VanDerWaalsContact O-CB 3.31Å; V465-A469 WeakPolarHBondContact O-CB 3.35Å; V465-A469 PolarHBondContact O-N 3.03Å
466	L	94.2	Very high	93.7	Very high	20 Å²	20	29.6 Å²	29.6	11%	0.105	15%	0.153	C	C	.	.	H	α-helix	trans	-61.7	-45	177.7	-71	172.8	0	0	0	112.2	I158 A161 V456 T460 D462 V463 E464 T470	I158-L466 HydrophobicContact CG1-CB 3.78Å; A161-L466 HydrophobicContact CB-CD1 3.78Å; V456-L466 HydrophobicContact CG1-CD2 3.52Å; T460-L466 HydrophobicContact CG2-CD1 4.19Å; T460-L466 HydrophobicContact CG2-CD2 4.04Å; T460-L466 HydrophobicContact CG2-CG 4.23Å; D462-L466 WeakPolarHBondContact O-CG 3.32Å; D462-L466 PolarHBondContact O-N 3.19Å; V463-L466 PolarHBondContact O-N 3.32Å; E464-L466 PolarHBondContact O-N 2.89Å; L466-T470 WeakPolarHBondContact O-CB 3.19Å; L466-T470 PolarHBondContact O-N 3.29Å; L466-T470 VanDerWaalsContact O-N 3.08Å; L466-T470 PolarHBondContact O-OG1 3.48Å
467	I	94.6	Very high	93.6	Very high	1 Å²	1	27.5 Å²	27.5	1%	0.005	14%	0.14	C	C	.	.	H	α-helix	trans	-65.5	-46.9	177	-73.7	171.9	0	0	0	110.6	A27 I158 T281 Y284 V463 E464 A469 T470 G471	A27-I467 HydrophobicContact CB-CD1 3.53Å; I158-I467 HydrophobicContact CD1-CB 4.38Å; I158-I467 HydrophobicContact CD1-CG1 3.65Å; I158-I467 HydrophobicContact CG1-CG1 3.85Å; I158-I467 HydrophobicContact CG2-CD1 4.13Å; I158-I467 HydrophobicContact CG2-CG1 3.84Å; T281-I467 HydrophobicContact CG2-CG2 3.93Å; Y284-I467 HydrophobicContact CD1-CG1 4.5Å; Y284-I467 HydrophobicContact CD1-CG2 3.72Å; Y284-I467 HydrophobicContact CE1-CG1 4.44Å; Y284-I467 HydrophobicContact CE1-CG2 4.46Å; Y284-I467 HydrophobicContact CG-CG2 3.83Å; V463-I467 HydrophobicContact CG1-CD1 3.6Å; V463-I467 HydrophobicContact CG1-CG1 4.24Å; V463-I467 WeakPolarHBondContact O-CB 3.29Å; V463-I467 WeakPolarHBondContact O-CG1 3.06Å; V463-I467 PolarHBondContact O-N 3.27Å; E464-I467 PolarHBondContact O-N 3.23Å; I467-A469 PolarHBondContact O-N 3.17Å; I467-T470 PolarHBondContact O-N 3.3Å; I467-G471 PolarHBondContact O-N 2.87Å
468	S	92.6	Very high	93.6	Very high	0 Å²	0	27.5 Å²	27.5	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-58.3	-49.2	180	176.6	0	0	0	0	111.7	T276 N277 G280 E464 V465 G471 S472	T276-S468 PolarHBondContact O-OG 3.08Å; N277-S468 WeakPolarHBondContact CA-OG 3.46Å; N277-S468 PolarHBondContact OD1-OG 3.04Å; G280-S468 WeakPolarHBondContact CA-O 3.49Å; E464-S468 WeakPolarHBondContact O-CB 2.99Å; E464-S468 PolarHBondContact O-N 2.98Å; V465-S468 PolarHBondContact O-N 3.13Å; S468-G471 PolarHBondContact O-N 3.5Å; S468-S472 WeakPolarHBondContact O-CB 3.42Å; S468-S472 PolarHBondContact O-N 3.46Å; S468-S472 PolarHBondContact O-OG 3.3Å
469	A	92.7	Very high	93.5	Very high	34 Å²	34	24.2 Å²	24.2	28%	0.281	13%	0.126	S	C	.	.	H	α-helix	trans	-63.7	-44.8	178	0	0	0	0	0	111.8	V465 I467 G471 S472 Y473	V465-A469 VanDerWaalsContact O-CB 3.31Å; V465-A469 WeakPolarHBondContact O-CB 3.35Å; V465-A469 PolarHBondContact O-N 3.03Å; I467-A469 PolarHBondContact O-N 3.17Å; A469-G471 PolarHBondContact O-N 3.43Å; A469-S472 PolarHBondContact O-N 2.63Å; A469-Y473 WeakPolarHBondContact O-CD2 3.37Å; A469-Y473 PolarHBondContact O-N 3.47Å
470	T	94.8	Very high	93.6	Very high	15 Å²	15	17 Å²	17	9%	0.092	9%	0.094	C	C	.	.	I	π-helix	trans	-61.7	-45.8	179.6	-58.2	0	0	0	0	111.4	Y151 G154 I158 Y284 L466 I467 A474 G475	Y151-T470 HydrophobicContact CD2-CG2 3.84Å; Y151-T470 HydrophobicContact CE2-CG2 4.2Å; G154-T470 WeakPolarHBondContact CA-OG1 3.12Å; I158-T470 HydrophobicContact CD1-CG2 4.45Å; Y284-T470 HydrophobicContact CD2-CG2 4.07Å; Y284-T470 HydrophobicContact CE2-CG2 4.07Å; L466-T470 WeakPolarHBondContact O-CB 3.19Å; L466-T470 PolarHBondContact O-N 3.29Å; L466-T470 VanDerWaalsContact O-N 3.08Å; L466-T470 PolarHBondContact O-OG1 3.48Å; I467-T470 PolarHBondContact O-N 3.3Å; T470-A474 PolarHBondContact O-N 3.23Å; T470-G475 PolarHBondContact O-N 2.97Å
471	G	93.9	Very high	93.7	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	9%	0.088	C	C	.	.	I	π-helix	trans	-67	-45.3	178	0	0	0	0	0	113.1	I283 I467 S468 A469 Y473 G475 V476	I283-G471 WeakPolarHBondContact CG2-O 3.34Å; I467-G471 PolarHBondContact O-N 2.87Å; S468-G471 PolarHBondContact O-N 3.5Å; A469-G471 PolarHBondContact O-N 3.43Å; G471-Y473 PolarHBondContact O-N 2.97Å; G471-G475 CarbonylContact O-C 3.55Å; G471-G475 WeakPolarHBondContact O-CA 3.5Å; G471-G475 PolarHBondContact O-N 2.68Å; G471-V476 PolarHBondContact O-N 3.24Å; G471-V476 VanDerWaalsContact O-N 3.11Å
472	S	92.6	Very high	93.8	Very high	0 Å²	0	15.2 Å²	15.2	0%	0	8%	0.083	C	C	.	.	I	π-helix	trans	-68.4	-29.7	-172.1	-63.7	0	0	0	0	114.7	G280 S468 A469 V476	G280-S472 WeakPolarHBondContact CA-OG 3.33Å; S468-S472 WeakPolarHBondContact O-CB 3.42Å; S468-S472 PolarHBondContact O-N 3.46Å; S468-S472 PolarHBondContact O-OG 3.3Å; A469-S472 PolarHBondContact O-N 2.63Å; S472-V476 WeakPolarHBondContact O-CG2 3.24Å
473	Y	92.9	Very high	94	Very high	93 Å²	93	12.4 Å²	12.4	37%	0.365	7%	0.068	S	C	.	.	I	π-helix	trans	-106.4	-65	-179.2	-65	-74.6	0	0	0	111.9	A469 G471 G477 V529 T530	A469-Y473 WeakPolarHBondContact O-CD2 3.37Å; A469-Y473 PolarHBondContact O-N 3.47Å; G471-Y473 PolarHBondContact O-N 2.97Å; Y473-G477 PolarHBondContact O-N 3.18Å; Y473-V529 HydrophobicContact CE2-CG1 4.08Å; Y473-T530 PolarHBondContact OH-OG1 3.42Å
474	A	94.8	Very high	94.1	Very high	4 Å²	4	12.6 Å²	12.6	3%	0.033	7%	0.069	C	C	.	.	I	π-helix	trans	-72.7	-39.9	-175.2	0	0	0	0	0	111.6	L150 Y151 T470 G477 I478	L150-A474 HydrophobicContact CB-CB 3.83Å; Y151-A474 HydrophobicContact CD2-CB 4.48Å; T470-A474 PolarHBondContact O-N 3.23Å; A474-G477 PolarHBondContact O-N 2.88Å; A474-I478 WeakPolarHBondContact O-CG1 3.05Å; A474-I478 PolarHBondContact O-N 3.32Å
475	G	94.6	Very high	94.3	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.083	C	C	.	.	I	π-helix	trans	-58.6	-50.9	174.3	0	0	0	0	0	112.4	T470 G471 G477 I478 Q479	T470-G475 PolarHBondContact O-N 2.97Å; G471-G475 CarbonylContact O-C 3.55Å; G471-G475 WeakPolarHBondContact O-CA 3.5Å; G471-G475 PolarHBondContact O-N 2.68Å; G475-G477 VanDerWaalsContact C-N 3.28Å; G475-G477 PolarHBondContact O-N 3Å; G475-I478 PolarHBondContact O-N 3.22Å; G475-Q479 WeakPolarHBondContact O-CB 3.27Å; G475-Q479 PolarHBondContact O-N 3Å
476	V	95.4	Very high	94.6	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-55.5	-42	177.1	169.7	0	0	0	0	112.3	F279 I283 G471 S472 I478 Y480 I481 A522 I526	F279-V476 HydrophobicContact CE1-CG2 4.22Å; F279-V476 HydrophobicContact CZ-CG2 4.1Å; I283-V476 HydrophobicContact CD1-CG2 3.49Å; I283-V476 VanDerWaalsContact CD1-CG2 3.49Å; G471-V476 PolarHBondContact O-N 3.24Å; G471-V476 VanDerWaalsContact O-N 3.11Å; S472-V476 WeakPolarHBondContact O-CG2 3.24Å; V476-I478 PolarHBondContact O-N 2.64Å; V476-Y480 HydrophobicContact CB-CD2 4.37Å; V476-Y480 HydrophobicContact CG1-CD2 4.09Å; V476-Y480 HydrophobicContact CG2-CD2 4.21Å; V476-Y480 HydrophobicContact CG2-CE2 4.41Å; V476-Y480 WeakPolarHBondContact O-CB 3.29Å; V476-Y480 PolarHBondContact O-N 2.88Å; V476-I481 HydrophobicContact CG1-CD1 4.31Å; V476-I481 HydrophobicContact CG1-CG1 4.36Å; V476-I481 PolarHBondContact O-N 2.89Å; V476-I481 VanDerWaalsContact O-N 3.16Å; V476-A522 HydrophobicContact CG1-CB 3.79Å; V476-I526 HydrophobicContact CB-CD1 4.46Å; V476-I526 HydrophobicContact CB-CG1 4.34Å; V476-I526 HydrophobicContact CG1-CD1 3.69Å; V476-I526 HydrophobicContact CG1-CG1 3.84Å
477	G	95.2	Very high	94.6	Very high	2 Å²	2	12.5 Å²	12.5	2%	0.021	6%	0.061	C	C	.	.	I	π-helix	trans	-57.6	-49.1	177.7	0	0	0	0	0	112.7	Y473 A474 G475 I481 V482	Y473-G477 PolarHBondContact O-N 3.18Å; A474-G477 PolarHBondContact O-N 2.88Å; G475-G477 VanDerWaalsContact C-N 3.28Å; G475-G477 PolarHBondContact O-N 3Å; G477-I481 PolarHBondContact O-N 3.41Å; G477-V482 WeakPolarHBondContact O-CG2 3.44Å; G477-V482 PolarHBondContact O-N 3.4Å
478	I	94.1	Very high	94.6	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	8%	0.081	C	C	.	.	I	π-helix	trans	-83.5	-32.9	-175.1	-53.9	156.9	0	0	0	112.5	F144 C147 M148 Y151 M287 H290 A474 G475 V476 P483	F144-I478 HydrophobicContact CE2-CG2 4.35Å; C147-I478 HydrophobicContact CB-CD1 4.29Å; C147-I478 HydrophobicContact CB-CG1 3.7Å; M148-I478 HydrophobicContact CG-CD1 4.27Å; M148-I478 HydrophobicContact CG-CG1 4.44Å; M148-I478 HydrophobicContact SD-CD1 3.6Å; M148-I478 HydrophobicContact SD-CG1 4.08Å; M148-I478 HydrophobicContact SD-CG2 4.17Å; Y151-I478 HydrophobicContact CD1-CD1 4.44Å; Y151-I478 HydrophobicContact CG-CD1 3.94Å; M287-I478 HydrophobicContact CE-CB 3.38Å; M287-I478 HydrophobicContact CE-CD1 3.39Å; M287-I478 HydrophobicContact CE-CG1 3.98Å; M287-I478 HydrophobicContact CE-CG2 3.47Å; M287-I478 VanDerWaalsContact CE-CG2 3.47Å; M287-I478 HydrophobicContact SD-CB 4.4Å; M287-I478 HydrophobicContact SD-CG2 4.39Å; H290-I478 HydrophobicContact CB-CG2 3.96Å; A474-I478 WeakPolarHBondContact O-CG1 3.05Å; A474-I478 PolarHBondContact O-N 3.32Å; G475-I478 PolarHBondContact O-N 3.22Å; V476-I478 PolarHBondContact O-N 2.64Å; I478-P483 WeakPolarHBondContact O-CD 3.4Å; I478-P483 VanDerWaalsContact O-CG 3.28Å; I478-P483 WeakPolarHBondContact O-CG 3.5Å
479	Q	95.1	Very high	94.7	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	9%	0.093	C	C	.	.	I	π-helix	trans	-84.8	-32	-174.5	-174.1	167	-27.9	0	0	112.7	S51 N54 I283 M287 G475	S51-Q479 PolarHBondContact OG-NE2 3.05Å; N54-Q479 WeakPolarHBondContact CB-O 3.26Å; I283-Q479 PolarHBondContact O-OE1 2.99Å; I283-Q479 VanDerWaalsContact O-OE1 3.11Å; M287-Q479 HydrophobicContact SD-CB 4.04Å; G475-Q479 WeakPolarHBondContact O-CB 3.27Å; G475-Q479 PolarHBondContact O-N 3Å
480	Y	95.6	Very high	94.6	Very high	0 Å²	0	19 Å²	19	0%	0	8%	0.079	C	C	.	.	I	π-helix	trans	-121.3	-55.7	-174.6	-55.4	-41.7	0	0	0	113	M50 N54 I283 V476 T484 W521 A522	M50-Y480 HydrophobicContact CB-CE1 3.9Å; N54-Y480 HydrophobicContact CB-CD1 4.47Å; N54-Y480 VanDerWaalsContact ND2-CD1 3.32Å; N54-Y480 WeakPolarHBondContact ND2-CD1 3.3Å; N54-Y480 PolarHBondContact OD1-O 3.47Å; I283-Y480 HydrophobicContact CD1-CD2 4.41Å; I283-Y480 HydrophobicContact CD1-CE2 3.49Å; I283-Y480 VanDerWaalsContact CD1-CE2 3.49Å; I283-Y480 HydrophobicContact CG1-CE2 4.18Å; V476-Y480 HydrophobicContact CB-CD2 4.37Å; V476-Y480 HydrophobicContact CG1-CD2 4.09Å; V476-Y480 HydrophobicContact CG2-CD2 4.21Å; V476-Y480 HydrophobicContact CG2-CE2 4.41Å; V476-Y480 WeakPolarHBondContact O-CB 3.29Å; V476-Y480 PolarHBondContact O-N 2.88Å; Y480-T484 WeakPolarHBondContact O-CB 3.19Å; Y480-T484 PolarHBondContact O-N 3.33Å; Y480-T484 VanDerWaalsContact O-N 3.14Å; Y480-T484 PolarHBondContact O-OG1 3.44Å; Y480-W521 AromaticContact CD2-CD1 3.9Å; Y480-W521 AromaticContact CE2-CD1 3.56Å; Y480-W521 AromaticContact CE2-NE1 3.46Å; Y480-W521 AromaticContact CZ-CD1 3.78Å; Y480-W521 AromaticContact CZ-NE1 3.58Å; Y480-A522 HydrophobicContact CD2-CB 4.39Å
481	I	96	Very high	94.6	Very high	24 Å²	24	19.5 Å²	19.5	12%	0.123	8%	0.08	C	C	.	.	I	π-helix	trans	-65.1	-53.7	-172.1	-60.2	177.8	0	0	0	110.9	F143 V476 G477 T484 W485 A522 I526	F143-I481 HydrophobicContact CE1-CB 4.1Å; F143-I481 HydrophobicContact CE1-CG2 3.62Å; F143-I481 HydrophobicContact CZ-CB 4.25Å; F143-I481 HydrophobicContact CZ-CD1 4.11Å; F143-I481 HydrophobicContact CZ-CG2 3.85Å; V476-I481 HydrophobicContact CG1-CD1 4.31Å; V476-I481 HydrophobicContact CG1-CG1 4.36Å; V476-I481 PolarHBondContact O-N 2.89Å; V476-I481 VanDerWaalsContact O-N 3.16Å; G477-I481 PolarHBondContact O-N 3.41Å; I481-T484 PolarHBondContact O-N 3.1Å; I481-W485 WeakPolarHBondContact O-CB 3.14Å; I481-W485 PolarHBondContact O-N 2.88Å; I481-A522 HydrophobicContact CD1-CB 4.46Å; I481-A522 HydrophobicContact CG1-CB 3.75Å; I481-I526 HydrophobicContact CD1-CD1 4.02Å
482	V	95.1	Very high	94.4	Very high	1 Å²	1	27.6 Å²	27.6	1%	0.006	11%	0.11	C	C	.	.	H	α-helix	trans	-61.8	-52	-177.4	168.9	0	0	0	0	112.2	V132 F143 F144 G477 T484 W485 L486	V132-V482 HydrophobicContact CG2-CG1 3.87Å; F143-V482 HydrophobicContact CD1-CG2 3.8Å; F143-V482 HydrophobicContact CE1-CG2 3.74Å; F144-V482 HydrophobicContact CB-CG2 4.25Å; F144-V482 HydrophobicContact CD2-CB 4.5Å; F144-V482 HydrophobicContact CD2-CG1 3.92Å; F144-V482 HydrophobicContact CD2-CG2 4.14Å; G477-V482 WeakPolarHBondContact O-CG2 3.44Å; G477-V482 PolarHBondContact O-N 3.4Å; V482-T484 VanDerWaalsContact C-N 3.32Å; V482-T484 PolarHBondContact O-N 3Å; V482-W485 PolarHBondContact O-N 3.01Å; V482-L486 HydrophobicContact CG1-CD1 3.64Å; V482-L486 HydrophobicContact CG1-CG 4.26Å; V482-L486 WeakPolarHBondContact O-CB 3.25Å; V482-L486 VanDerWaalsContact O-CG 3.24Å; V482-L486 WeakPolarHBondContact O-CG 3.19Å; V482-L486 PolarHBondContact O-N 3.08Å
483	P	95.3	Very high	94.2	Very high	0 Å²	0	29.5 Å²	29.5	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-59.6	-41.2	179.3	-27.7	37.9	0	0	0	113.1	N54 F57 V58 I478 L486 A487	N54-P483 HydrophobicContact CB-CB 4.12Å; N54-P483 HydrophobicContact CB-CG 4.43Å; F57-P483 HydrophobicContact CB-CB 4.32Å; V58-P483 HydrophobicContact CG2-CB 3.73Å; V58-P483 HydrophobicContact CG2-CG 3.69Å; I478-P483 WeakPolarHBondContact O-CD 3.4Å; I478-P483 VanDerWaalsContact O-CG 3.28Å; I478-P483 WeakPolarHBondContact O-CG 3.5Å; P483-L486 PolarHBondContact O-N 2.97Å; P483-A487 WeakPolarHBondContact O-CB 3.29Å; P483-A487 PolarHBondContact O-N 2.92Å
484	T	96	Very high	93.8	Very high	6 Å²	6	25.8 Å²	25.8	4%	0.037	11%	0.109	C	C	.	.	H	α-helix	trans	-65.6	-43.4	179	-56.6	0	0	0	0	111.6	N54 Y480 I481 V482 W488 L515 S518 F519	N54-T484 PolarHBondContact OD1-OG1 3.24Å; N54-T484 VanDerWaalsContact OD1-OG1 3.06Å; Y480-T484 WeakPolarHBondContact O-CB 3.19Å; Y480-T484 PolarHBondContact O-N 3.33Å; Y480-T484 VanDerWaalsContact O-N 3.14Å; Y480-T484 PolarHBondContact O-OG1 3.44Å; I481-T484 PolarHBondContact O-N 3.1Å; V482-T484 VanDerWaalsContact C-N 3.32Å; V482-T484 PolarHBondContact O-N 3Å; T484-W488 VanDerWaalsContact O-CB 3.31Å; T484-W488 WeakPolarHBondContact O-CB 3.2Å; T484-W488 PolarHBondContact O-N 2.72Å; T484-L515 HydrophobicContact CG2-CB 4.02Å; T484-L515 HydrophobicContact CG2-CD2 4.07Å; T484-L515 VanDerWaalsContact CG2-O 3.25Å; T484-L515 WeakPolarHBondContact CG2-O 3.19Å; T484-S518 VanDerWaalsContact OG1-CB 3.27Å; T484-S518 WeakPolarHBondContact OG1-CB 3.3Å; T484-S518 PolarHBondContact OG1-OG 3.17Å; T484-F519 HydrophobicContact CG2-CB 4.13Å
485	W	95.6	Very high	93.4	Very high	83 Å²	83	31.1 Å²	31.1	31%	0.314	13%	0.131	S	C	.	.	H	α-helix	trans	-65.9	-41.5	179	-168.1	7.8	0	0	0	111.7	L136 V139 I481 V482 W488 K489	L136-W485 HydrophobicContact CD1-CB 4.09Å; L136-W485 HydrophobicContact CD1-CD2 3.52Å; L136-W485 HydrophobicContact CD1-CE3 3.68Å; L136-W485 HydrophobicContact CD1-CG 3.71Å; L136-W485 HydrophobicContact CD1-CZ3 4.3Å; L136-W485 HydrophobicContact CD2-CD2 4Å; L136-W485 HydrophobicContact CD2-CG 3.84Å; L136-W485 HydrophobicContact CG-CD2 4.3Å; L136-W485 HydrophobicContact CG-CG 4.44Å; V139-W485 HydrophobicContact CG1-CH2 4.43Å; I481-W485 WeakPolarHBondContact O-CB 3.14Å; I481-W485 PolarHBondContact O-N 2.88Å; V482-W485 PolarHBondContact O-N 3.01Å; W485-W488 PolarHBondContact O-N 3.46Å; W485-K489 WeakPolarHBondContact O-CB 3.29Å; W485-K489 PolarHBondContact O-N 3.37Å
486	L	94.8	Very high	93	Very high	0 Å²	0	32.2 Å²	32.2	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-62.3	-50.7	175.6	-69	167.2	0	0	0	112	V61 L128 V132 L135 L136 V482 P483 W488 K489 V490	V61-L486 HydrophobicContact CB-CB 4.34Å; V61-L486 HydrophobicContact CG1-CB 3.96Å; V61-L486 HydrophobicContact CG1-CD1 4.21Å; V61-L486 HydrophobicContact CG1-CD2 4.43Å; V61-L486 HydrophobicContact CG1-CG 4.43Å; V61-L486 HydrophobicContact CG2-CB 3.59Å; L128-L486 HydrophobicContact CD1-CD1 4Å; V132-L486 HydrophobicContact CB-CD2 4.38Å; V132-L486 HydrophobicContact CG2-CD1 3.85Å; V132-L486 HydrophobicContact CG2-CD2 3.94Å; V132-L486 HydrophobicContact CG2-CG 4.32Å; L135-L486 HydrophobicContact CB-CD2 3.97Å; L135-L486 HydrophobicContact CD1-CD2 3.79Å; L136-L486 HydrophobicContact CD1-CD2 3.68Å; L136-L486 HydrophobicContact CD1-CG 4.03Å; L136-L486 HydrophobicContact CD2-CD2 4.48Å; L136-L486 HydrophobicContact CG-CD2 3.75Å; V482-L486 HydrophobicContact CG1-CD1 3.64Å; V482-L486 HydrophobicContact CG1-CG 4.26Å; V482-L486 WeakPolarHBondContact O-CB 3.25Å; V482-L486 VanDerWaalsContact O-CG 3.24Å; V482-L486 WeakPolarHBondContact O-CG 3.19Å; V482-L486 PolarHBondContact O-N 3.08Å; P483-L486 PolarHBondContact O-N 2.97Å; L486-W488 VanDerWaalsContact C-N 3.32Å; L486-W488 PolarHBondContact O-N 3Å; L486-K489 PolarHBondContact O-N 3.43Å; L486-K489 VanDerWaalsContact O-N 3.16Å; L486-V490 WeakPolarHBondContact O-CG2 3.46Å; L486-V490 PolarHBondContact O-N 3.39Å
487	A	95.3	Very high	92.5	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-63.5	-38.7	179.8	0	0	0	0	0	111.9	F57 V61 P483 K489 V490 R491 L515	F57-A487 HydrophobicContact CB-CB 3.83Å; F57-A487 HydrophobicContact CD1-CB 4.29Å; F57-A487 HydrophobicContact CD2-CB 4.37Å; F57-A487 HydrophobicContact CG-CB 3.93Å; V61-A487 HydrophobicContact CG2-CB 4.25Å; P483-A487 WeakPolarHBondContact O-CB 3.29Å; P483-A487 PolarHBondContact O-N 2.92Å; A487-K489 VanDerWaalsContact C-N 3.34Å; A487-K489 PolarHBondContact O-N 2.9Å; A487-V490 PolarHBondContact O-N 3.31Å; A487-R491 WeakPolarHBondContact O-CB 3.43Å; A487-R491 WeakPolarHBondContact O-CG 3.39Å; A487-R491 PolarHBondContact O-N 3.11Å; A487-L515 HydrophobicContact CB-CD2 3.73Å
488	W	95.2	Very high	92.1	Very high	112 Å²	112	33.9 Å²	33.9	42%	0.424	15%	0.147	S	C	.	.	H	α-helix	trans	-58.9	-45.3	172.8	177.3	82.5	0	0	0	112.1	T484 W485 L486 R492 L515	T484-W488 VanDerWaalsContact O-CB 3.31Å; T484-W488 WeakPolarHBondContact O-CB 3.2Å; T484-W488 PolarHBondContact O-N 2.72Å; W485-W488 PolarHBondContact O-N 3.46Å; L486-W488 VanDerWaalsContact C-N 3.32Å; L486-W488 PolarHBondContact O-N 3Å; W488-R492 VanDerWaalsContact O-CB 3.32Å; W488-R492 WeakPolarHBondContact O-CB 3.16Å; W488-R492 PolarHBondContact O-N 3.04Å; W488-R492 VanDerWaalsContact O-N 3.14Å; W488-L515 HydrophobicContact CB-CD1 4.11Å
489	K	93.8	Very high	91.8	Very high	57 Å²	57	40.1 Å²	40.1	25%	0.248	18%	0.176	C	C	.	.	H	α-helix	trans	-66.7	-44	179.6	-172.6	76.7	177.2	-179.4	0	111.8	L135 L136 W485 L486 A487 R492 S493	L135-K489 HydrophobicContact CB-CG 4.33Å; L135-K489 WeakPolarHBondContact O-CE 3.3Å; L135-K489 VanDerWaalsContact O-CG 3.31Å; L135-K489 WeakPolarHBondContact O-CG 3.44Å; L136-K489 HydrophobicContact CD2-CB 3.79Å; L136-K489 HydrophobicContact CD2-CG 4.05Å; W485-K489 WeakPolarHBondContact O-CB 3.29Å; W485-K489 PolarHBondContact O-N 3.37Å; L486-K489 PolarHBondContact O-N 3.43Å; L486-K489 VanDerWaalsContact O-N 3.16Å; A487-K489 VanDerWaalsContact C-N 3.34Å; A487-K489 PolarHBondContact O-N 2.9Å; K489-R492 PolarHBondContact O-N 2.89Å; K489-S493 WeakPolarHBondContact CE-OG 3.26Å; K489-S493 PolarHBondContact NZ-OG 3.46Å; K489-S493 WeakPolarHBondContact O-CB 3.31Å; K489-S493 PolarHBondContact O-N 3.39Å
490	V	91.6	Very high	91.4	Very high	1 Å²	1	41.6 Å²	41.6	1%	0.006	19%	0.188	C	C	.	.	H	α-helix	trans	-60.5	-50.6	176.8	169.1	0	0	0	0	111	V61 A64 L135 L486 A487 R492 Y494 Y498	V61-V490 HydrophobicContact CG2-CG2 4.07Å; A64-V490 HydrophobicContact CB-CG1 3.59Å; A64-V490 HydrophobicContact CB-CG2 4.23Å; L135-V490 HydrophobicContact CD1-CG2 3.46Å; L135-V490 VanDerWaalsContact CD1-CG2 3.46Å; L135-V490 HydrophobicContact CD2-CG2 3.83Å; L135-V490 HydrophobicContact CG-CG2 4.29Å; L486-V490 WeakPolarHBondContact O-CG2 3.46Å; L486-V490 PolarHBondContact O-N 3.39Å; A487-V490 PolarHBondContact O-N 3.31Å; V490-R492 PolarHBondContact O-N 3.27Å; V490-Y494 CarbonylContact O-C 3.55Å; V490-Y494 VanDerWaalsContact O-C 3.3Å; V490-Y494 WeakPolarHBondContact O-CA 3.34Å; V490-Y494 WeakPolarHBondContact O-CB 3.49Å; V490-Y494 PolarHBondContact O-N 2.94Å; V490-Y494 VanDerWaalsContact O-N 3.09Å; V490-Y498 HydrophobicContact CG1-CD2 4.26Å
491	R	93.3	Very high	90.8	Very high	27 Å²	27	42.1 Å²	42.1	10%	0.102	19%	0.191	C	C	.	.	H	α-helix	trans	-65.4	-26.2	-177.2	-68	173.3	-171.3	-165.6	-3	113.5	E60 A487 Y498 F509 R510	E60-R491 IonicContact OE1-CZ 2.76Å; E60-R491 IonicContact OE1-NE 3.51Å; E60-R491 PolarHBondContact OE1-NE 3.38Å; E60-R491 IonicContact OE1-NH2 2.78Å; E60-R491 PolarHBondContact OE1-NH2 3.2Å; E60-R491 IonicContact OE2-CZ 3.97Å; E60-R491 IonicContact OE2-NE 3.2Å; E60-R491 IonicContact OE2-NH2 3.29Å; E60-R491 PolarHBondContact OE2-NH2 2.9Å; A487-R491 WeakPolarHBondContact O-CB 3.43Å; A487-R491 WeakPolarHBondContact O-CG 3.39Å; A487-R491 PolarHBondContact O-N 3.11Å; R491-Y498 HydrophobicContact CG-CD1 4.45Å; R491-Y498 HydrophobicContact CG-CD2 4.14Å; R491-Y498 HydrophobicContact CG-CE1 4.18Å; R491-Y498 HydrophobicContact CG-CE2 3.85Å; R491-Y498 HydrophobicContact CG-CG 4.43Å; R491-F509 PolarHBondContact NH1-O 2.96Å; R491-F509 PolarHBondContact NH2-O 3.3Å; R491-F509 VanDerWaalsContact NH2-O 3.12Å; R491-R510 PolarHBondContact NH1-O 3.05Å; R491-R510 VanDerWaalsContact NH1-O 3.12Å
492	R	90.7	Very high	90.2	Very high	170 Å²	170	41.9 Å²	41.9	64%	0.642	19%	0.191	S	C	*	.	H	α-helix	trans	-97.8	-54.8	-177.5	-172.3	175.1	-179.3	168.8	0.2	113.4	W488 K489 V490	W488-R492 VanDerWaalsContact O-CB 3.32Å; W488-R492 WeakPolarHBondContact O-CB 3.16Å; W488-R492 PolarHBondContact O-N 3.04Å; W488-R492 VanDerWaalsContact O-N 3.14Å; K489-R492 PolarHBondContact O-N 2.89Å; V490-R492 PolarHBondContact O-N 3.27Å
493	S	88.1	Confident	89.7	Confident	39 Å²	39	46.7 Å²	46.7	27%	0.273	22%	0.22	S	C	.	.	H	α-helix	trans	-80.6	-40.3	-175.5	-66.1	0	0	0	0	111.5	H94 K489 K495	H94-S493 PolarHBondContact CD2-O 3.24Å; H94-S493 PolarHBondContact NE2-O 3.05Å; K489-S493 WeakPolarHBondContact CE-OG 3.26Å; K489-S493 PolarHBondContact NZ-OG 3.46Å; K489-S493 WeakPolarHBondContact O-CB 3.31Å; K489-S493 PolarHBondContact O-N 3.39Å; S493-K495 VanDerWaalsContact C-N 3.31Å; S493-K495 PolarHBondContact O-N 3.49Å
494	Y	85.3	Confident	89.1	Confident	16 Å²	16	48.9 Å²	48.9	6%	0.063	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.5	36.9	-179.8	-66	-97.7	0	0	0	112.1	H94 I97 L135 V490 A496 L497 Y498	H94-Y494 AromaticContact NE2-CE2 3.9Å; H94-Y494 AromaticContact NE2-CZ 3.99Å; I97-Y494 HydrophobicContact CD1-CD1 4.5Å; I97-Y494 HydrophobicContact CD1-CE1 4.39Å; L135-Y494 HydrophobicContact CD2-CD2 3.72Å; L135-Y494 HydrophobicContact CD2-CE2 3.37Å; V490-Y494 CarbonylContact O-C 3.55Å; V490-Y494 VanDerWaalsContact O-C 3.3Å; V490-Y494 WeakPolarHBondContact O-CA 3.34Å; V490-Y494 WeakPolarHBondContact O-CB 3.49Å; V490-Y494 PolarHBondContact O-N 2.94Å; V490-Y494 VanDerWaalsContact O-N 3.09Å; Y494-A496 PolarHBondContact O-N 3.48Å; Y494-L497 HydrophobicContact CD1-CD2 4.37Å; Y494-L497 PolarHBondContact O-N 3.49Å; Y494-L497 VanDerWaalsContact O-N 3.16Å; Y494-Y498 WeakPolarHBondContact O-CB 2.96Å; Y494-Y498 PolarHBondContact O-N 3.07Å
495	K	86.1	Confident	88.5	Confident	115 Å²	115	49.3 Å²	49.3	50%	0.5	23%	0.231	S	C	.	.	H	α-helix	trans	-55.8	-45.6	-170.4	-177.1	177.1	170.7	-176.9	0	113.2	S493 L497 Y498 E499	S493-K495 VanDerWaalsContact C-N 3.31Å; S493-K495 PolarHBondContact O-N 3.49Å; K495-L497 PolarHBondContact O-N 2.88Å; K495-Y498 PolarHBondContact O-N 3.46Å; K495-E499 WeakPolarHBondContact CE-OE1 3.29Å; K495-E499 HydrophobicContact CG-CG 4.32Å; K495-E499 IonicContact NZ-OE1 3.25Å; K495-E499 WeakPolarHBondContact O-CB 3.47Å; K495-E499 WeakPolarHBondContact O-CG 3.39Å; K495-E499 PolarHBondContact O-N 3.19Å
496	A	84.6	Confident	88.3	Confident	24 Å²	24	45.8 Å²	45.8	20%	0.198	22%	0.219	C	C	.	.	H	α-helix	trans	-62.6	-43.3	179.9	0	0	0	0	0	112	I101 Y494 Y498 E499 A500	I101-A496 HydrophobicContact CD1-CB 3.71Å; Y494-A496 PolarHBondContact O-N 3.48Å; A496-Y498 VanDerWaalsContact C-N 3.35Å; A496-E499 PolarHBondContact O-N 2.82Å; A496-A500 WeakPolarHBondContact O-CB 3.29Å; A496-A500 PolarHBondContact O-N 2.76Å
497	L	85.4	Confident	88.1	Confident	1 Å²	1	45.8 Å²	45.8	1%	0.005	22%	0.219	C	C	.	.	H	α-helix	trans	-65.7	-39.3	176.3	-176.7	66.5	0	0	0	111.9	A64 A67 F120 Y494 K495 A500 M501	A64-L497 WeakPolarHBondContact O-CD2 3.38Å; A67-L497 HydrophobicContact CB-CD1 4.01Å; A67-L497 HydrophobicContact CB-CD2 4.5Å; F120-L497 HydrophobicContact CE1-CD1 3.85Å; F120-L497 HydrophobicContact CE1-CG 4.32Å; F120-L497 HydrophobicContact CZ-CD1 4.2Å; Y494-L497 HydrophobicContact CD1-CD2 4.37Å; Y494-L497 PolarHBondContact O-N 3.49Å; Y494-L497 VanDerWaalsContact O-N 3.16Å; K495-L497 PolarHBondContact O-N 2.88Å; L497-A500 PolarHBondContact O-N 3.36Å; L497-M501 PolarHBondContact O-N 3.43Å
498	Y	87	Confident	88	Confident	35 Å²	35	49.4 Å²	49.4	14%	0.137	24%	0.243	C	C	.	.	H	α-helix	trans	-66.7	-40.3	176.2	175.2	-99.9	0	0	0	112.2	E60 V490 R491 Y494 K495 A496 A500 M501 V506	E60-Y498 HydrophobicContact CG-CE2 4.12Å; V490-Y498 HydrophobicContact CG1-CD2 4.26Å; R491-Y498 HydrophobicContact CG-CD1 4.45Å; R491-Y498 HydrophobicContact CG-CD2 4.14Å; R491-Y498 HydrophobicContact CG-CE1 4.18Å; R491-Y498 HydrophobicContact CG-CE2 3.85Å; R491-Y498 HydrophobicContact CG-CG 4.43Å; Y494-Y498 WeakPolarHBondContact O-CB 2.96Å; Y494-Y498 PolarHBondContact O-N 3.07Å; K495-Y498 PolarHBondContact O-N 3.46Å; A496-Y498 VanDerWaalsContact C-N 3.35Å; Y498-A500 VanDerWaalsContact C-N 3.31Å; Y498-A500 PolarHBondContact O-N 2.78Å; Y498-M501 VanDerWaalsContact O-CB 3.3Å; Y498-M501 WeakPolarHBondContact O-CB 3.48Å; Y498-M501 PolarHBondContact O-N 3.36Å; Y498-V506 HydrophobicContact CE2-CG1 3.89Å; Y498-V506 HydrophobicContact CE2-CG2 4.38Å; Y498-V506 WeakPolarHBondContact OH-CG1 3.44Å
499	E	87.2	Confident	88	Confident	131 Å²	131	45.3 Å²	45.3	61%	0.612	23%	0.228	S	C	*	.	H	α-helix	trans	-67.4	-30.8	176.7	-75.6	175.7	164.3	0	0	112.6	K495 A496 M501	K495-E499 WeakPolarHBondContact CE-OE1 3.29Å; K495-E499 HydrophobicContact CG-CG 4.32Å; K495-E499 IonicContact NZ-OE1 3.25Å; K495-E499 WeakPolarHBondContact O-CB 3.47Å; K495-E499 WeakPolarHBondContact O-CG 3.39Å; K495-E499 PolarHBondContact O-N 3.19Å; A496-E499 PolarHBondContact O-N 2.82Å; E499-M501 VanDerWaalsContact C-N 3.31Å
500	A	86.6	Confident	87.8	Confident	32 Å²	32	49 Å²	49	26%	0.264	24%	0.24	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79.5	-8.2	174.3	0	0	0	0	0	114.2	L115 F120 A496 L497 Y498	L115-A500 HydrophobicContact CD1-CB 3.89Å; F120-A500 WeakPolarHBondContact CE2-O 3.38Å; F120-A500 HydrophobicContact CZ-CB 4.18Å; F120-A500 WeakPolarHBondContact CZ-O 3.22Å; A496-A500 WeakPolarHBondContact O-CB 3.29Å; A496-A500 PolarHBondContact O-N 2.76Å; L497-A500 PolarHBondContact O-N 3.36Å; Y498-A500 VanDerWaalsContact C-N 3.31Å; Y498-A500 PolarHBondContact O-N 2.78Å
501	M	84.3	Confident	87.9	Confident	11 Å²	11	51.8 Å²	51.8	5%	0.054	26%	0.26	C	S	.	.	S	Bend	trans	-72	131.1	-176.5	-173.4	-177.3	-69.8	0	0	111.7	A64 F120 L497 Y498 E499 Y505 V506	A64-M501 HydrophobicContact CB-CE 3.61Å; F120-M501 HydrophobicContact CD1-CB 4.12Å; F120-M501 HydrophobicContact CD1-CE 4.12Å; F120-M501 HydrophobicContact CD1-CG 3.84Å; F120-M501 HydrophobicContact CE1-CB 3.88Å; F120-M501 HydrophobicContact CE1-CE 4.45Å; F120-M501 HydrophobicContact CE1-CG 4.14Å; F120-M501 HydrophobicContact CG-CG 4.28Å; F120-M501 HydrophobicContact CZ-CB 4.31Å; L497-M501 PolarHBondContact O-N 3.43Å; Y498-M501 VanDerWaalsContact O-CB 3.3Å; Y498-M501 WeakPolarHBondContact O-CB 3.48Å; Y498-M501 PolarHBondContact O-N 3.36Å; E499-M501 VanDerWaalsContact C-N 3.31Å; M501-Y505 VanDerWaalsContact SD-C 3.53Å; M501-Y505 VanDerWaalsContact SD-CB 3.56Å; M501-Y505 VanDerWaalsContact SD-O 3.37Å; M501-V506 HydrophobicContact CB-CG2 3.9Å; M501-V506 HydrophobicContact CG-CG2 3.81Å; M501-V506 HydrophobicContact SD-CG2 3.65Å
502	P	83.6	Confident	87.8	Confident	18 Å²	18	55.5 Å²	55.5	12%	0.117	29%	0.286	C	S	.	.			trans	-55.6	143	173.5	-26.4	33.4	0	0	0	112.4	E117 F120 H504 Y505	E117-P502 HydrophobicContact CB-CG 4.39Å; E117-P502 HydrophobicContact CG-CG 4.1Å; F120-P502 HydrophobicContact CD2-CG 3.95Å; F120-P502 HydrophobicContact CE2-CG 4.46Å; P502-H504 WeakPolarHBondContact CB-CE1 3.27Å; P502-H504 WeakPolarHBondContact CB-ND1 3.31Å; P502-H504 PolarHBondContact O-N 3.3Å; P502-Y505 HydrophobicContact CB-CD2 4.12Å; P502-Y505 HydrophobicContact CG-CD2 4.18Å; P502-Y505 PolarHBondContact O-N 3.05Å
503	T	83.8	Confident	88	Confident	103 Å²	103	50.2 Å²	50.2	63%	0.632	28%	0.279	S	S	*	.	T	Hydrogen-bonded Turn	trans	-58.8	-21.9	-172.6	57.2	0	0	0	0	114.7
504	H	83.4	Confident	88.4	Confident	46 Å²	46	52.5 Å²	52.5	21%	0.213	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-80.8	-13.8	179.7	62.2	-95.5	0	0	0	114.3	E117 Y306 P502	E117-H504 IonicContact OE1-CE1 2.68Å; E117-H504 IonicContact OE1-ND1 3.63Å; E117-H504 IonicContact OE2-CE1 2.69Å; Y306-H504 VanDerWaalsContact CE2-O 3.28Å; Y306-H504 WeakPolarHBondContact CE2-O 3.42Å; P502-H504 WeakPolarHBondContact CB-CE1 3.27Å; P502-H504 WeakPolarHBondContact CB-ND1 3.31Å; P502-H504 PolarHBondContact O-N 3.3Å
505	Y	83.9	Confident	88.9	Confident	14 Å²	14	52.2 Å²	52.2	6%	0.055	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.8	-9.4	172.7	-67.5	-61	0	0	0	113.3	E60 S63 F120 K302 Y306 M501 P502	E60-Y505 WeakPolarHBondContact CA-O 3.29Å; S63-Y505 WeakPolarHBondContact OG-CD1 3.05Å; F120-Y505 HydrophobicContact CB-CD2 3.61Å; F120-Y505 HydrophobicContact CB-CE2 3.76Å; F120-Y505 HydrophobicContact CB-CG 4.35Å; K302-Y505 HydrophobicContact CB-CE1 4.25Å; Y306-Y505 VanDerWaalsContact OH-C 3.26Å; Y306-Y505 PolarHBondContact OH-O 3.08Å; M501-Y505 VanDerWaalsContact SD-C 3.53Å; M501-Y505 VanDerWaalsContact SD-CB 3.56Å; M501-Y505 VanDerWaalsContact SD-O 3.37Å; P502-Y505 HydrophobicContact CB-CD2 4.12Å; P502-Y505 HydrophobicContact CG-CD2 4.18Å; P502-Y505 PolarHBondContact O-N 3.05Å
506	V	89.6	Confident	89.4	Confident	9 Å²	9	49.2 Å²	49.2	6%	0.055	28%	0.278	C	S	.	.	S	Bend	trans	-88.9	136.2	176.8	179.2	0	0	0	0	109.5	Y306 Y498 M501 R510	Y306-V506 WeakPolarHBondContact CE2-O 3.32Å; Y498-V506 HydrophobicContact CE2-CG1 3.89Å; Y498-V506 HydrophobicContact CE2-CG2 4.38Å; Y498-V506 WeakPolarHBondContact OH-CG1 3.44Å; M501-V506 HydrophobicContact CB-CG2 3.9Å; M501-V506 HydrophobicContact CG-CG2 3.81Å; M501-V506 HydrophobicContact SD-CG2 3.65Å; V506-R510 HydrophobicContact CG1-CG 3.96Å
507	S	92.3	Very high	89.9	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	29%	0.285	C	S	.	.			trans	-56.5	140.3	176.1	172.2	0	0	0	0	110.6	T56 E60 Y306 F509 R510	T56-S507 WeakPolarHBondContact CB-OG 3.18Å; T56-S507 PolarHBondContact OG1-OG 3.09Å; E60-S507 WeakPolarHBondContact OE2-CB 3.46Å; E60-S507 PolarHBondContact OE2-N 3.38Å; Y306-S507 PolarHBondContact OH-N 3.18Å; S507-F509 PolarHBondContact O-N 2.98Å; S507-F509 VanDerWaalsContact O-N 3.12Å; S507-F509 PolarHBondContact OG-N 2.94Å; S507-R510 VanDerWaalsContact O-CG 3.22Å; S507-R510 WeakPolarHBondContact O-CG 3.47Å
508	P	92.8	Very high	90.4	Very high	77 Å²	77	51.3 Å²	51.3	50%	0.5	29%	0.285	S	S	.	.	S	Bend	trans	-60	-20.9	170.6	25.2	-33.2	0	0	0	112.2	T56 R510	T56-P508 HydrophobicContact CG2-CG 4.45Å; P508-R510 PolarHBondContact O-N 3.25Å
509	F	94.2	Very high	90.7	Very high	26 Å²	26	54.1 Å²	54.1	11%	0.114	30%	0.298	C	S	.	.			trans	-92.1	66.3	179.5	-56.4	-73.2	0	0	0	111.7	F49 F52 L53 T56 F57 R491 S507 W514	F49-F509 HydrophobicContact CE2-CE1 4.04Å; F49-F509 AromaticContact CE2-CZ 3.8Å; F49-F509 HydrophobicContact CE2-CZ 3.8Å; F49-F509 AromaticContact CZ-CE1 3.92Å; F49-F509 HydrophobicContact CZ-CE1 3.92Å; F49-F509 HydrophobicContact CZ-CZ 4.07Å; F52-F509 HydrophobicContact CD1-CE2 4.12Å; F52-F509 HydrophobicContact CD1-CZ 4.4Å; F52-F509 AromaticContact CE1-CE2 3.8Å; F52-F509 HydrophobicContact CE1-CE2 3.8Å; F52-F509 HydrophobicContact CE1-CZ 4.13Å; L53-F509 HydrophobicContact CB-CD2 4.27Å; L53-F509 HydrophobicContact CB-CE2 4.11Å; L53-F509 HydrophobicContact CD1-CD1 4.17Å; L53-F509 HydrophobicContact CD1-CD2 4.36Å; L53-F509 HydrophobicContact CD1-CE1 4.38Å; L53-F509 HydrophobicContact CD1-CG 4.15Å; L53-F509 HydrophobicContact CG-CD2 3.93Å; L53-F509 HydrophobicContact CG-CE2 4.23Å; L53-F509 HydrophobicContact CG-CG 4.12Å; T56-F509 HydrophobicContact CG2-CD2 4.4Å; T56-F509 HydrophobicContact CG2-CE2 4.31Å; F57-F509 HydrophobicContact CE1-CB 3.97Å; F57-F509 HydrophobicContact CZ-CB 4.37Å; R491-F509 PolarHBondContact NH1-O 2.96Å; R491-F509 PolarHBondContact NH2-O 3.3Å; R491-F509 VanDerWaalsContact NH2-O 3.12Å; S507-F509 PolarHBondContact O-N 2.98Å; S507-F509 VanDerWaalsContact O-N 3.12Å; S507-F509 PolarHBondContact OG-N 2.94Å; F509-W514 HydrophobicContact CB-CB 4.04Å; F509-W514 HydrophobicContact CB-CD2 4.37Å; F509-W514 HydrophobicContact CB-CG 3.77Å; F509-W514 AromaticContact CD1-CD2 3.78Å; F509-W514 HydrophobicContact CD1-CD2 3.78Å; F509-W514 AromaticContact CD1-CE2 3.61Å; F509-W514 HydrophobicContact CD1-CE3 4.29Å; F509-W514 HydrophobicContact CD1-CG 4.09Å; F509-W514 HydrophobicContact CD1-CH2 4.46Å; F509-W514 AromaticContact CD1-CZ2 3.98Å; F509-W514 HydrophobicContact CD1-CZ2 3.98Å; F509-W514 AromaticContact CD1-NE1 3.81Å; F509-W514 HydrophobicContact CE1-CH2 4.43Å; F509-W514 HydrophobicContact CE1-CZ2 4.26Å; F509-W514 HydrophobicContact CG-CD2 4.43Å; F509-W514 HydrophobicContact CG-CG 4.33Å
510	R	91.1	Very high	91.1	Very high	133 Å²	133	51.7 Å²	51.7	50%	0.502	30%	0.295	S	S	.	.			trans	-72.3	-31.1	-173	-60.8	-175.1	-178.4	-179.1	0.7	114.6	R491 V506 S507 P508	R491-R510 PolarHBondContact NH1-O 3.05Å; R491-R510 VanDerWaalsContact NH1-O 3.12Å; V506-R510 HydrophobicContact CG1-CG 3.96Å; S507-R510 VanDerWaalsContact O-CG 3.22Å; S507-R510 WeakPolarHBondContact O-CG 3.47Å; P508-R510 PolarHBondContact O-N 3.25Å
511	S	92.4	Very high	91.4	Very high	61 Å²	61	51.8 Å²	51.8	43%	0.427	29%	0.288	S	S	.	.	S	Bend	trans	-63.7	140.7	-178	-179.9	0	0	0	0	111.9	A513 W514	S511-A513 PolarHBondContact O-N 3.19Å; S511-A513 WeakPolarHBondContact OG-CB 3.34Å; S511-A513 PolarHBondContact OG-N 3.46Å; S511-W514 PolarHBondContact O-N 3.43Å
512	T	91.5	Very high	91.8	Very high	105 Å²	105	51.2 Å²	51.2	64%	0.644	29%	0.286	S	S	*	.	H	α-helix	trans	-62.1	-20.6	172.7	50.9	0	0	0	0	112.6	W514 L515 A516	T512-W514 PolarHBondContact O-N 3.3Å; T512-L515 WeakPolarHBondContact O-CB 3.33Å; T512-L515 PolarHBondContact O-N 2.93Å; T512-L515 VanDerWaalsContact O-N 3.16Å; T512-A516 PolarHBondContact O-N 3.32Å
513	A	95.2	Very high	92.2	Very high	59 Å²	59	54.2 Å²	54.2	49%	0.488	30%	0.3	S	S	.	.	H	α-helix	trans	-58.2	-35.2	174	0	0	0	0	0	112.5	S511 A516 L517	S511-A513 PolarHBondContact O-N 3.19Å; S511-A513 WeakPolarHBondContact OG-CB 3.34Å; S511-A513 PolarHBondContact OG-N 3.46Å; A513-A516 PolarHBondContact O-N 3.29Å; A513-L517 WeakPolarHBondContact O-CB 3.03Å; A513-L517 PolarHBondContact O-N 2.92Å
514	W	96.7	Very high	92.5	Very high	87 Å²	87	54.5 Å²	54.5	33%	0.33	29%	0.293	S	S	.	.	H	α-helix	trans	-70.6	-33.9	178.1	-65.6	115	0	0	0	112.7	F49 L53 F57 F509 S511 T512 L517 S518	F49-W514 AromaticContact CE1-CZ3 3.99Å; F49-W514 HydrophobicContact CE1-CZ3 3.99Å; F49-W514 HydrophobicContact CZ-CH2 4.12Å; F49-W514 AromaticContact CZ-CZ3 3.82Å; F49-W514 HydrophobicContact CZ-CZ3 3.82Å; L53-W514 HydrophobicContact CD1-CB 4.27Å; L53-W514 HydrophobicContact CD1-CD2 4.05Å; L53-W514 HydrophobicContact CD1-CE3 3.43Å; L53-W514 VanDerWaalsContact CD1-CE3 3.43Å; L53-W514 HydrophobicContact CD1-CG 4.43Å; L53-W514 HydrophobicContact CD1-CZ3 4.06Å; F57-W514 HydrophobicContact CZ-CB 4.07Å; F509-W514 HydrophobicContact CB-CB 4.04Å; F509-W514 HydrophobicContact CB-CD2 4.37Å; F509-W514 HydrophobicContact CB-CG 3.77Å; F509-W514 AromaticContact CD1-CD2 3.78Å; F509-W514 HydrophobicContact CD1-CD2 3.78Å; F509-W514 AromaticContact CD1-CE2 3.61Å; F509-W514 HydrophobicContact CD1-CE3 4.29Å; F509-W514 HydrophobicContact CD1-CG 4.09Å; F509-W514 HydrophobicContact CD1-CH2 4.46Å; F509-W514 AromaticContact CD1-CZ2 3.98Å; F509-W514 HydrophobicContact CD1-CZ2 3.98Å; F509-W514 AromaticContact CD1-NE1 3.81Å; F509-W514 HydrophobicContact CE1-CH2 4.43Å; F509-W514 HydrophobicContact CE1-CZ2 4.26Å; F509-W514 HydrophobicContact CG-CD2 4.43Å; F509-W514 HydrophobicContact CG-CG 4.33Å; S511-W514 PolarHBondContact O-N 3.43Å; T512-W514 PolarHBondContact O-N 3.3Å; W514-L517 HydrophobicContact CE3-CD2 3.74Å; W514-L517 HydrophobicContact CZ3-CD2 3.76Å; W514-S518 WeakPolarHBondContact O-CB 3.31Å; W514-S518 PolarHBondContact O-N 2.88Å
515	L	95.8	Very high	92.6	Very high	9 Å²	9	52.3 Å²	52.3	5%	0.047	28%	0.283	C	S	.	.	H	α-helix	trans	-66.8	-45.1	172.6	-61.4	172.8	0	0	0	110.5	F57 T484 A487 W488 T512 L517 S518 F519	F57-L515 HydrophobicContact CD2-CD2 3.94Å; F57-L515 HydrophobicContact CE1-CD2 4.23Å; F57-L515 HydrophobicContact CE2-CD2 3.52Å; F57-L515 HydrophobicContact CG-CD2 4.45Å; F57-L515 HydrophobicContact CZ-CD2 3.68Å; F57-L515 HydrophobicContact CZ-CG 4.39Å; T484-L515 HydrophobicContact CG2-CB 4.02Å; T484-L515 HydrophobicContact CG2-CD2 4.07Å; T484-L515 VanDerWaalsContact CG2-O 3.25Å; T484-L515 WeakPolarHBondContact CG2-O 3.19Å; A487-L515 HydrophobicContact CB-CD2 3.73Å; W488-L515 HydrophobicContact CB-CD1 4.11Å; T512-L515 WeakPolarHBondContact O-CB 3.33Å; T512-L515 PolarHBondContact O-N 2.93Å; T512-L515 VanDerWaalsContact O-N 3.16Å; L515-L517 PolarHBondContact O-N 3.26Å; L515-S518 PolarHBondContact O-N 2.82Å; L515-F519 WeakPolarHBondContact O-CB 3.36Å; L515-F519 PolarHBondContact O-N 3.29Å
516	A	95.4	Very high	92.8	Very high	53 Å²	53	53.9 Å²	53.9	44%	0.438	29%	0.292	S	S	.	.	H	α-helix	trans	-61.1	-44.7	176.2	0	0	0	0	0	111.5	T512 A513 S518 F519 C520	T512-A516 PolarHBondContact O-N 3.32Å; A513-A516 PolarHBondContact O-N 3.29Å; A516-S518 PolarHBondContact O-N 3.37Å; A516-F519 PolarHBondContact O-N 2.98Å; A516-C520 VanDerWaalsContact O-CB 3.28Å; A516-C520 WeakPolarHBondContact O-CB 3.43Å; A516-C520 PolarHBondContact O-N 3.4Å; A516-C520 PolarHBondContact O-SG 3.2Å
517	L	96	Very high	92.8	Very high	68 Å²	68	57.1 Å²	57.1	36%	0.356	31%	0.313	S	S	.	.	H	α-helix	trans	-57.2	-47.7	175.4	179.4	66.8	0	0	0	111.5	M50 A513 W514 L515 W521	M50-L517 HydrophobicContact CE-CG 4.24Å; M50-L517 HydrophobicContact SD-CD2 4.11Å; M50-L517 HydrophobicContact SD-CG 4.36Å; A513-L517 WeakPolarHBondContact O-CB 3.03Å; A513-L517 PolarHBondContact O-N 2.92Å; W514-L517 HydrophobicContact CE3-CD2 3.74Å; W514-L517 HydrophobicContact CZ3-CD2 3.76Å; L515-L517 PolarHBondContact O-N 3.26Å; L517-W521 WeakPolarHBondContact O-CB 3.1Å; L517-W521 PolarHBondContact O-N 3.2Å
518	S	95.5	Very high	92.4	Very high	0 Å²	0	59 Å²	59	0%	0	32%	0.323	C	S	.	.	H	α-helix	trans	-63.4	-43.8	179.6	-171.1	0	0	0	0	113	N54 T484 W514 L515 A516 W521 A522	N54-S518 VanDerWaalsContact CG-OG 3.25Å; N54-S518 PolarHBondContact ND2-OG 3.1Å; N54-S518 PolarHBondContact OD1-OG 3.05Å; T484-S518 VanDerWaalsContact OG1-CB 3.27Å; T484-S518 WeakPolarHBondContact OG1-CB 3.3Å; T484-S518 PolarHBondContact OG1-OG 3.17Å; W514-S518 WeakPolarHBondContact O-CB 3.31Å; W514-S518 PolarHBondContact O-N 2.88Å; L515-S518 PolarHBondContact O-N 2.82Å; A516-S518 PolarHBondContact O-N 3.37Å; S518-W521 PolarHBondContact O-N 3.35Å; S518-A522 PolarHBondContact O-N 2.94Å
519	F	94.1	Very high	92	Very high	95 Å²	95	55.4 Å²	55.4	42%	0.417	30%	0.3	S	S	.	.	H	α-helix	trans	-67.4	-46	178.2	-167.6	-103.6	0	0	0	112.1	T484 L515 A516 W521 A522 L523	T484-F519 HydrophobicContact CG2-CB 4.13Å; L515-F519 WeakPolarHBondContact O-CB 3.36Å; L515-F519 PolarHBondContact O-N 3.29Å; A516-F519 PolarHBondContact O-N 2.98Å; F519-W521 VanDerWaalsContact C-N 3.3Å; F519-W521 PolarHBondContact O-N 3.48Å; F519-A522 PolarHBondContact O-N 3.47Å; F519-L523 HydrophobicContact CD1-CD1 3.93Å; F519-L523 HydrophobicContact CD1-CG 4.39Å; F519-L523 HydrophobicContact CE1-CD1 3.55Å; F519-L523 HydrophobicContact CE1-CG 4.14Å; F519-L523 HydrophobicContact CZ-CD1 4.26Å; F519-L523 HydrophobicContact CZ-CG 4.5Å; F519-L523 WeakPolarHBondContact O-CG 3.19Å; F519-L523 PolarHBondContact O-N 3.02Å
520	C	94.6	Very high	91.6	Very high	80 Å²	80	56 Å²	56	54%	0.541	31%	0.306	S	S	.	.	H	α-helix	trans	-61.7	-39.6	175.7	-70.8	0	0	0	0	111.6	A516 L523 F524	A516-C520 VanDerWaalsContact O-CB 3.28Å; A516-C520 WeakPolarHBondContact O-CB 3.43Å; A516-C520 PolarHBondContact O-N 3.4Å; A516-C520 PolarHBondContact O-SG 3.2Å; C520-L523 PolarHBondContact O-N 3.48Å; C520-F524 VanDerWaalsContact O-CB 3.24Å; C520-F524 WeakPolarHBondContact O-CB 2.97Å; C520-F524 PolarHBondContact O-N 2.88Å
521	W	93.2	Very high	91.3	Very high	33 Å²	33	53.5 Å²	53.5	13%	0.125	31%	0.305	C	S	.	.	H	α-helix	trans	-60.3	-49.8	173.8	178.1	-112.7	0	0	0	111.2	F46 I47 M50 F279 Y480 L517 S518 F519 L523 F524 S525	F46-W521 HydrophobicContact CD1-CD2 4.45Å; F46-W521 HydrophobicContact CD1-CE3 4.45Å; F46-W521 AromaticContact CD1-CH2 3.61Å; F46-W521 HydrophobicContact CD1-CH2 3.61Å; F46-W521 AromaticContact CD1-CZ2 3.6Å; F46-W521 HydrophobicContact CD1-CZ2 3.6Å; F46-W521 HydrophobicContact CD1-CZ3 4.06Å; F46-W521 AromaticContact CE1-CD2 3.53Å; F46-W521 HydrophobicContact CE1-CD2 3.53Å; F46-W521 AromaticContact CE1-CE2 3.52Å; F46-W521 AromaticContact CE1-CE3 3.51Å; F46-W521 HydrophobicContact CE1-CE3 3.51Å; F46-W521 HydrophobicContact CE1-CG 4.27Å; F46-W521 AromaticContact CE1-CH2 3.49Å; F46-W521 HydrophobicContact CE1-CH2 3.49Å; F46-W521 VanDerWaalsContact CE1-CH2 3.49Å; F46-W521 AromaticContact CE1-CZ2 3.51Å; F46-W521 HydrophobicContact CE1-CZ2 3.51Å; F46-W521 AromaticContact CE1-CZ3 3.49Å; F46-W521 HydrophobicContact CE1-CZ3 3.49Å; F46-W521 VanDerWaalsContact CE1-CZ3 3.49Å; F46-W521 HydrophobicContact CZ-CD2 4.31Å; F46-W521 HydrophobicContact CZ-CE3 4.15Å; F46-W521 HydrophobicContact CZ-CZ3 4.33Å; I47-W521 HydrophobicContact CG1-CZ2 4.16Å; M50-W521 HydrophobicContact CE-CB 3.85Å; M50-W521 HydrophobicContact CE-CG 4.01Å; F279-W521 HydrophobicContact CD2-CZ2 4.2Å; F279-W521 HydrophobicContact CE2-CH2 4.49Å; F279-W521 AromaticContact CE2-CZ2 3.69Å; F279-W521 HydrophobicContact CE2-CZ2 3.69Å; Y480-W521 AromaticContact CD2-CD1 3.9Å; Y480-W521 AromaticContact CE2-CD1 3.56Å; Y480-W521 AromaticContact CE2-NE1 3.46Å; Y480-W521 AromaticContact CZ-CD1 3.78Å; Y480-W521 AromaticContact CZ-NE1 3.58Å; L517-W521 WeakPolarHBondContact O-CB 3.1Å; L517-W521 PolarHBondContact O-N 3.2Å; S518-W521 PolarHBondContact O-N 3.35Å; F519-W521 VanDerWaalsContact C-N 3.3Å; F519-W521 PolarHBondContact O-N 3.48Å; W521-L523 VanDerWaalsContact C-N 3.31Å; W521-L523 PolarHBondContact O-N 2.99Å; W521-F524 AromaticContact CE3-CD1 3.86Å; W521-F524 HydrophobicContact CE3-CD1 3.86Å; W521-F524 HydrophobicContact CE3-CE1 4.39Å; W521-F524 AromaticContact CZ3-CD1 3.72Å; W521-F524 HydrophobicContact CZ3-CD1 3.72Å; W521-F524 AromaticContact CZ3-CE1 3.81Å; W521-F524 PolarHBondContact O-N 3.24Å; W521-F524 HydrophobicContact CZ3-CE1 3.81Å; W521-S525 PolarHBondContact O-N 3.13Å; W521-S525 PolarHBondContact O-OG 3.27Å; W521-S525 WeakPolarHBondContact O-CB 3.41Å
522	A	93.1	Very high	90.7	Very high	0 Å²	0	51.9 Å²	51.9	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-56.8	-42.6	178	0	0	0	0	0	112.9	V476 Y480 I481 S518 F519 S525 I526	V476-A522 HydrophobicContact CG1-CB 3.79Å; Y480-A522 HydrophobicContact CD2-CB 4.39Å; I481-A522 HydrophobicContact CD1-CB 4.46Å; I481-A522 HydrophobicContact CG1-CB 3.75Å; S518-A522 PolarHBondContact O-N 2.94Å; F519-A522 PolarHBondContact O-N 3.47Å; A522-S525 WeakPolarHBondContact O-CB 3.18Å; A522-I526 WeakPolarHBondContact O-CG1 3.34Å; A522-I526 PolarHBondContact O-N 2.91Å; A522-I526 VanDerWaalsContact O-N 3.12Å
523	L	91.8	Very high	89.9	Confident	80 Å²	80	50 Å²	50	42%	0.419	28%	0.275	S	S	.	.	H	α-helix	trans	-67.1	-48.6	176.6	-68.3	-179.4	0	0	0	112	F519 C520 W521 S525 I526 C527	F519-L523 HydrophobicContact CD1-CD1 3.93Å; F519-L523 HydrophobicContact CD1-CG 4.39Å; F519-L523 HydrophobicContact CE1-CD1 3.55Å; F519-L523 HydrophobicContact CE1-CG 4.14Å; F519-L523 HydrophobicContact CZ-CD1 4.26Å; F519-L523 HydrophobicContact CZ-CG 4.5Å; F519-L523 WeakPolarHBondContact O-CG 3.19Å; F519-L523 PolarHBondContact O-N 3.02Å; C520-L523 PolarHBondContact O-N 3.48Å; W521-L523 VanDerWaalsContact C-N 3.31Å; W521-L523 PolarHBondContact O-N 2.99Å; L523-S525 VanDerWaalsContact C-N 3.27Å; L523-S525 PolarHBondContact O-N 3.39Å; L523-I526 PolarHBondContact O-N 3.38Å; L523-C527 WeakPolarHBondContact O-CB 3.25Å; L523-C527 PolarHBondContact O-SG 2.91Å; L523-C527 PolarHBondContact O-N 3.45Å
524	F	89.6	Confident	89.2	Confident	110 Å²	110	54.4 Å²	54.4	48%	0.482	28%	0.284	S	S	.	.	H	α-helix	trans	-55.9	-45.3	177.8	173.8	-104.3	0	0	0	111.5	C520 W521 C527 I528	C520-F524 VanDerWaalsContact O-CB 3.24Å; C520-F524 WeakPolarHBondContact O-CB 2.97Å; C520-F524 PolarHBondContact O-N 2.88Å; W521-F524 AromaticContact CE3-CD1 3.86Å; W521-F524 HydrophobicContact CE3-CD1 3.86Å; W521-F524 HydrophobicContact CE3-CE1 4.39Å; W521-F524 AromaticContact CZ3-CD1 3.72Å; W521-F524 HydrophobicContact CZ3-CD1 3.72Å; W521-F524 AromaticContact CZ3-CE1 3.81Å; W521-F524 PolarHBondContact O-N 3.24Å; W521-F524 HydrophobicContact CZ3-CE1 3.81Å; F524-C527 PolarHBondContact O-N 3.02Å; F524-I528 PolarHBondContact O-N 2.77Å; F524-I528 WeakPolarHBondContact O-CG1 3.31Å; F524-I528 HydrophobicContact CZ-CG1 4.3Å; F524-I528 HydrophobicContact CZ-CD1 3.07Å; F524-I528 HydrophobicContact CE2-CD1 3.4Å; F524-I528 HydrophobicContact CG-CD1 4.2Å; F524-I528 VanDerWaalsContact CE2-CD1 3.4Å; F524-I528 HydrophobicContact CE1-CD1 3.31Å; F524-I528 HydrophobicContact CD2-CG1 4.48Å; F524-I528 HydrophobicContact CD2-CD1 3.96Å; F524-I528 HydrophobicContact CD1-CD1 3.89Å; F524-I528 HydrophobicContact CE2-CG1 4.23Å
525	S	85.7	Confident	88.4	Confident	0 Å²	0	57 Å²	57	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-56.4	-53.8	175.1	-74.5	0	0	0	0	113.6	F279 W521 A522 L523 C527 I528 V529	F279-S525 WeakPolarHBondContact CE2-OG 3.34Å; F279-S525 WeakPolarHBondContact CZ-OG 3.34Å; W521-S525 PolarHBondContact O-N 3.13Å; W521-S525 PolarHBondContact O-OG 3.27Å; W521-S525 WeakPolarHBondContact O-CB 3.41Å; A522-S525 WeakPolarHBondContact O-CB 3.18Å; L523-S525 VanDerWaalsContact C-N 3.27Å; L523-S525 PolarHBondContact O-N 3.39Å; S525-C527 VanDerWaalsContact C-N 3.3Å; S525-C527 PolarHBondContact O-N 3.35Å; S525-I528 PolarHBondContact O-N 3.02Å; S525-V529 VanDerWaalsContact O-CG2 3.32Å; S525-V529 WeakPolarHBondContact O-CG2 3.28Å; S525-V529 PolarHBondContact O-N 3.42Å; S525-V529 VanDerWaalsContact O-N 3.09Å
526	I	89	Confident	86.9	Confident	47 Å²	47	61.9 Å²	61.9	24%	0.241	33%	0.327	C	S	.	.	H	α-helix	trans	-62.3	-42.4	179.2	-69.5	166.2	0	0	0	110.2	V476 I481 A522 L523 T530	V476-I526 HydrophobicContact CB-CD1 4.46Å; V476-I526 HydrophobicContact CB-CG1 4.34Å; V476-I526 HydrophobicContact CG1-CD1 3.69Å; V476-I526 HydrophobicContact CG1-CG1 3.84Å; I481-I526 HydrophobicContact CD1-CD1 4.02Å; A522-I526 WeakPolarHBondContact O-CG1 3.34Å; A522-I526 PolarHBondContact O-N 2.91Å; A522-I526 VanDerWaalsContact O-N 3.12Å; L523-I526 PolarHBondContact O-N 3.38Å; I526-T530 WeakPolarHBondContact O-CB 3.21Å; I526-T530 PolarHBondContact O-N 3.27Å; I526-T530 PolarHBondContact O-OG1 2.68Å
527	C	88.2	Confident	84.7	Confident	76 Å²	76	65.7 Å²	65.7	51%	0.514	35%	0.351	S	S	.	.	H	α-helix	trans	-60.5	-50.1	178.8	-72.2	0	0	0	0	111.9	L523 F524 S525 T530 V531	L523-C527 WeakPolarHBondContact O-CB 3.25Å; L523-C527 PolarHBondContact O-SG 2.91Å; L523-C527 PolarHBondContact O-N 3.45Å; F524-C527 PolarHBondContact O-N 3.02Å; S525-C527 VanDerWaalsContact C-N 3.3Å; S525-C527 PolarHBondContact O-N 3.35Å; C527-T530 PolarHBondContact O-N 3.04Å; C527-V531 VanDerWaalsContact O-CG2 3.26Å; C527-V531 WeakPolarHBondContact O-CG2 3.37Å; C527-V531 PolarHBondContact O-N 2.97Å; C527-V531 WeakPolarHBondContact O-CB 3.49Å
528	I	84.7	Confident	84.2	Confident	41 Å²	41	65.6 Å²	65.6	21%	0.21	35%	0.351	C	S	.	.	H	α-helix	trans	-61.8	-47.9	-179.5	-75.6	176.8	0	0	0	111.3	F275 F524 S525 T530 V531 N532	F275-I528 HydrophobicContact CD1-CG2 3.56Å; F275-I528 HydrophobicContact CE1-CD1 4.36Å; F275-I528 HydrophobicContact CE1-CG2 3.77Å; F524-I528 PolarHBondContact O-N 2.77Å; F524-I528 WeakPolarHBondContact O-CG1 3.31Å; F524-I528 HydrophobicContact CZ-CG1 4.3Å; F524-I528 HydrophobicContact CZ-CD1 3.07Å; F524-I528 HydrophobicContact CE2-CD1 3.4Å; F524-I528 HydrophobicContact CG-CD1 4.2Å; F524-I528 VanDerWaalsContact CE2-CD1 3.4Å; F524-I528 HydrophobicContact CE1-CD1 3.31Å; F524-I528 HydrophobicContact CD2-CG1 4.48Å; F524-I528 HydrophobicContact CD2-CD1 3.96Å; F524-I528 HydrophobicContact CD1-CD1 3.89Å; F524-I528 HydrophobicContact CE2-CG1 4.23Å; S525-I528 PolarHBondContact O-N 3.02Å; I528-T530 VanDerWaalsContact C-N 3.28Å; I528-T530 PolarHBondContact O-N 3.15Å; I528-V531 PolarHBondContact O-N 3.4Å; I528-N532 PolarHBondContact O-N 2.66Å; I528-N532 WeakPolarHBondContact O-CB 3.26Å
529	V	83.5	Confident	83.6	Confident	0 Å²	0	69.1 Å²	69.1	0%	0	37%	0.369	C	S	.	.	H	α-helix	trans	-62.2	-41.8	-178.8	170.9	0	0	0	0	110.7	T276 F279 Y473 S525 N532 H533	T276-V529 HydrophobicContact CG2-CB 4.18Å; T276-V529 HydrophobicContact CG2-CG1 3.61Å; T276-V529 HydrophobicContact CG2-CG2 4.05Å; F279-V529 HydrophobicContact CD1-CG2 3.48Å; F279-V529 VanDerWaalsContact CD1-CG2 3.48Å; F279-V529 HydrophobicContact CE1-CG2 3.83Å; F279-V529 HydrophobicContact CG-CG2 4.47Å; Y473-V529 HydrophobicContact CE2-CG1 4.08Å; S525-V529 VanDerWaalsContact O-CG2 3.32Å; S525-V529 WeakPolarHBondContact O-CG2 3.28Å; S525-V529 PolarHBondContact O-N 3.42Å; S525-V529 VanDerWaalsContact O-N 3.09Å; V529-N532 PolarHBondContact O-N 3.39Å; V529-H533 WeakPolarHBondContact O-CB 3.02Å; V529-H533 PolarHBondContact O-CD2 3.38Å; V529-H533 PolarHBondContact O-N 3.32Å
530	T	87	Confident	83	Confident	40 Å²	40	67.6 Å²	67.6	25%	0.245	37%	0.367	C	S	.	.	H	α-helix	trans	-64.9	-44.9	178.5	-58	0	0	0	0	111.4	Y473 I526 C527 I528 H533 F534	Y473-T530 PolarHBondContact OH-OG1 3.42Å; I526-T530 WeakPolarHBondContact O-CB 3.21Å; I526-T530 PolarHBondContact O-N 3.27Å; I526-T530 PolarHBondContact O-OG1 2.68Å; C527-T530 PolarHBondContact O-N 3.04Å; I528-T530 VanDerWaalsContact C-N 3.28Å; I528-T530 PolarHBondContact O-N 3.15Å; T530-H533 PolarHBondContact O-N 2.92Å; T530-F534 PolarHBondContact O-N 2.72Å; T530-F534 VanDerWaalsContact O-N 3.08Å; T530-F534 WeakPolarHBondContact O-CD2 3.29Å; T530-F534 HydrophobicContact CG2-CE2 3.48Å; T530-F534 HydrophobicContact CG2-CD2 3.78Å; T530-F534 VanDerWaalsContact CG2-CE2 3.48Å
531	V	84.8	Confident	82.3	Confident	80 Å²	80	66.9 Å²	66.9	49%	0.485	36%	0.356	S	S	.	.	H	α-helix	trans	-61.2	-47.1	176.8	168.8	0	0	0	0	111	C527 I528 H533 F534 M535	C527-V531 VanDerWaalsContact O-CG2 3.26Å; C527-V531 WeakPolarHBondContact O-CG2 3.37Å; C527-V531 PolarHBondContact O-N 2.97Å; C527-V531 WeakPolarHBondContact O-CB 3.49Å; I528-V531 PolarHBondContact O-N 3.4Å; V531-H533 PolarHBondContact O-N 3.21Å; V531-F534 PolarHBondContact O-N 3.35Å; V531-F534 VanDerWaalsContact O-N 3.13Å; V531-M535 HydrophobicContact CG1-CG 4.37Å; V531-M535 HydrophobicContact CG1-SD 3.82Å; V531-M535 WeakPolarHBondContact O-CG 3.36Å; V531-M535 PolarHBondContact O-N 3.5Å
532	N	79.7	Confident	81.6	Confident	27 Å²	27	69 Å²	69	14%	0.144	37%	0.371	C	S	.	.	H	α-helix	trans	-63.3	-41.7	179.6	-73.9	-7.5	0	0	0	111.5	T276 I528 V529 F534 M535 D536	T276-N532 WeakPolarHBondContact OG1-CB 3.39Å; T276-N532 PolarHBondContact OG1-ND2 3.45Å; I528-N532 PolarHBondContact O-N 2.66Å; I528-N532 WeakPolarHBondContact O-CB 3.26Å; V529-N532 PolarHBondContact O-N 3.39Å; N532-F534 VanDerWaalsContact C-N 3.28Å; N532-F534 PolarHBondContact O-N 3.19Å; N532-M535 PolarHBondContact O-N 3.3Å; N532-D536 WeakPolarHBondContact O-CB 3.26Å; N532-D536 PolarHBondContact O-N 3.21Å
533	H	74.8	Confident	80.9	Confident	65 Å²	65	73.6 Å²	73.6	30%	0.301	40%	0.396	S	S	.	.	H	α-helix	trans	-60	-36.2	173.6	-88.4	-54.7	0	0	0	113.3	V529 T530 V531 M535 S537	V529-H533 WeakPolarHBondContact O-CB 3.02Å; V529-H533 PolarHBondContact O-CD2 3.38Å; V529-H533 PolarHBondContact O-N 3.32Å; T530-H533 PolarHBondContact O-N 2.92Å; V531-H533 PolarHBondContact O-N 3.21Å; H533-M535 VanDerWaalsContact C-N 3.34Å; H533-S537 WeakPolarHBondContact O-CB 3.36Å; H533-S537 PolarHBondContact O-N 3.06Å; H533-S537 PolarHBondContact O-OG 3.3Å
534	F	80.8	Confident	80.1	Confident	152 Å²	152	73.1 Å²	73.1	67%	0.667	39%	0.394	S	S	*	.	H	α-helix	trans	-74.2	-21.9	174.3	-79.7	-63.6	0	0	0	113.8	T530 V531 N532 S537	T530-F534 PolarHBondContact O-N 2.72Å; T530-F534 VanDerWaalsContact O-N 3.08Å; T530-F534 WeakPolarHBondContact O-CD2 3.29Å; T530-F534 HydrophobicContact CG2-CE2 3.48Å; T530-F534 HydrophobicContact CG2-CD2 3.78Å; T530-F534 VanDerWaalsContact CG2-CE2 3.48Å; V531-F534 PolarHBondContact O-N 3.35Å; V531-F534 VanDerWaalsContact O-N 3.13Å; N532-F534 VanDerWaalsContact C-N 3.28Å; N532-F534 PolarHBondContact O-N 3.19Å; F534-S537 PolarHBondContact O-OG 2.87Å
535	M	78.4	Confident	79.4	Confident	142 Å²	142	70.3 Å²	70.3	70%	0.7	39%	0.387	S	S	*	.	H	α-helix	trans	-87.5	-29.7	177.7	-71.7	-179.3	61.6	0	0	112.6	V531 N532 H533	V531-M535 HydrophobicContact CG1-CG 4.37Å; V531-M535 HydrophobicContact CG1-SD 3.82Å; V531-M535 WeakPolarHBondContact O-CG 3.36Å; V531-M535 PolarHBondContact O-N 3.5Å; N532-M535 PolarHBondContact O-N 3.3Å; H533-M535 VanDerWaalsContact C-N 3.34Å
536	D	65.4	Low	78.9	Confident	110 Å²	110	76.2 Å²	76.2	59%	0.588	42%	0.419	S	S	*	.	H	α-helix	trans	-85.5	-15.9	177.9	-66.6	-28	0	0	0	113	N532	N532-D536 WeakPolarHBondContact O-CB 3.26Å; N532-D536 PolarHBondContact O-N 3.21Å
537	S	50	Low	77.9	Confident	134 Å²	134	78.8 Å²	78.8	94%	0.937	44%	0.436	S	S	*	.			trans	-87.3	0	173.1	67.1	0	0	0	0	112.4	H533 F534	H533-S537 WeakPolarHBondContact O-CB 3.36Å; H533-S537 PolarHBondContact O-N 3.06Å; H533-S537 PolarHBondContact O-OG 3.3Å; F534-S537 PolarHBondContact O-OG 2.87Å

Retrieved 537 of 537 residues in 453.3 ms (Link to these results)

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