A0A077ZF48_TRITR Loading...

WD40 and Trypsin domain containing protein

AlphaFold DB , UniProt , Accession A0A077ZF48, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 921 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M21.5Very low53.6Low215 Ų215112.4 Ų112.4100%1.05955%0.548SS*.  0131.80-78174.5-179.700104.9D3M1-D3 PolarHBondContact O-N 3.32Å
2H25.1Very low56.3Low162 Ų162120.7 Ų120.775%0.7557%0.569SS**  trans-58.2119.1-153.1-59.5-63.1000114.3
3D28.6Very low58.5Low104 Ų104123.1 Ų123.156%0.55657%0.569SS**  trans-99.6120.1-164.4-68.9-51.6000114.4M1 I5M1-D3 PolarHBondContact O-N 3.32Å; D3-I5 PolarHBondContact O-N 2.98Å
4R43.3Very low60.2Low101 Ų101119.3 Ų119.338%0.38156%0.555SS.*THydrogen-bonded Turntrans41.8-6152.2-87.4-179.1-176.3174.3-3.1127.1E75 T146R4-E75 IonicContact CZ-OE1 3.53Å; R4-E75 VanDerWaalsContact CZ-OE1 3.24Å; R4-E75 IonicContact CZ-OE2 2.83Å; R4-E75 IonicContact NH1-OE1 3.44Å; R4-E75 PolarHBondContact NH1-OE1 2.8Å; R4-E75 IonicContact NH1-OE2 3.57Å; R4-E75 PolarHBondContact NH1-OE2 2.74Å; R4-E75 IonicContact NH2-OE1 2.79Å; R4-E75 PolarHBondContact NH2-OE1 2.97Å; R4-T146 HydrophobicContact CB-CG2 4.15Å; R4-T146 HydrophobicContact CG-CG2 3.75Å; R4-T146 VanDerWaalsContact N-CG2 3.29Å
5I52.4Low62.2Low71 Ų71115 Ų11536%0.36454%0.544SS..THydrogen-bonded Turntrans-144.3143.1148.1-70.1-179.2000101.4D3 Y7 G8D3-I5 PolarHBondContact O-N 2.98Å; I5-Y7 PolarHBondContact O-N 2.73Å; I5-G8 PolarHBondContact O-N 3.16Å
6S52.7Low64.2Low46 Ų46110.5 Ų110.532%0.32252%0.524SS..THydrogen-bonded Turntrans-50.2112.5-179.9-64.40000110.1G8S6-G8 VanDerWaalsContact C-N 3.33Å; S6-G8 PolarHBondContact O-N 3.36Å
7Y57.6Low66Low180 Ų180104.8 Ų104.871%0.70650%0.498SS*.THydrogen-bonded Turntrans67.712.8-175.5-44.7-81.9000117.8I5I5-Y7 PolarHBondContact O-N 2.73Å
8G67.7Low67.8Low27 Ų27100 Ų10028%0.27847%0.474SS..  trans-81.6-175.817500000114.3I5 S6I5-G8 PolarHBondContact O-N 3.16Å; S6-G8 VanDerWaalsContact C-N 3.33Å; S6-G8 PolarHBondContact O-N 3.36Å
9W74Confident69.2Low205 Ų20595.3 Ų95.378%0.77745%0.452SS*.  trans-130.3152.6173.360.582.6000111.1A11 F139W9-A11 PolarHBondContact O-N 3.42Å; W9-F139 HydrophobicContact CZ2-CE1 4.38Å
10V80.9Confident70.6Confident91 Ų9190.6 Ų90.655%0.55243%0.43SS*.PPolyproline II helixtrans-64.1127.3176.1-176.70000109.6
11A86.2Confident71.6Confident34 Ų3487.9 Ų87.928%0.28142%0.416SS..PPolyproline II helixtrans-60.2157.3174.800000111W9 L16 H74W9-A11 PolarHBondContact O-N 3.42Å; A11-L16 HydrophobicContact CB-CD1 3.79Å; A11-L16 HydrophobicContact CB-CG 4.34Å; A11-H74 PolarHBondContact O-CE1 2.88Å
12R86Confident75Confident212 Ų21277.7 Ų77.780%0.837%0.365SS*.PPolyproline II helixtrans-73.8147.3172.6-67.6-179.3-178.5176.41.2108.7N14 S15R12-N14 PolarHBondContact O-N 3.38Å; R12-S15 PolarHBondContact N-OG 2.99Å; R12-S15 WeakPolarHBondContact O-CB 3.35Å; R12-S15 PolarHBondContact O-N 3.44Å; R12-S15 PolarHBondContact O-OG 3.16Å
13R84.5Confident77.9Confident152 Ų15271.2 Ų71.257%0.57434%0.336SS*.THydrogen-bonded Turntrans-51.8136.8172.2-82.3-178.6-168.5-81.9-4.5109.7S15 H74 E80R13-S15 PolarHBondContact O-N 2.92Å; R13-S15 VanDerWaalsContact O-N 3.07Å; R13-H74 HydrophobicContact CG-CB 4.27Å; R13-H74 VanDerWaalsContact CG-CD2 3.43Å; R13-H74 WeakPolarHBondContact CG-CD2 3.39Å; R13-E80 IonicContact CZ-OE1 3.55Å; R13-E80 IonicContact NH1-OE1 3.88Å; R13-E80 PolarHBondContact NH1-OE1 2.82Å; R13-E80 IonicContact NH1-OE2 4Å; R13-E80 IonicContact NH2-OE1 2.77Å
14N82.6Confident80.4Confident70 Ų7066.4 Ų66.437%0.37431%0.31SS..THydrogen-bonded Turntrans62.96.2179.2-49.5-6.6000114.9R12 L16 E119R12-N14 PolarHBondContact O-N 3.38Å; N14-L16 VanDerWaalsContact C-N 3.33Å; N14-L16 PolarHBondContact O-N 3.3Å; N14-E119 WeakPolarHBondContact OD1-CG 3.3Å
15S90Very high81.4Confident55 Ų5564.3 Ų64.339%0.38531%0.309SS..SBendtrans-78.2-17-17871.60000114.1R12 R13 P17R12-S15 PolarHBondContact N-OG 2.99Å; R12-S15 WeakPolarHBondContact O-CB 3.35Å; R12-S15 PolarHBondContact O-N 3.44Å; R12-S15 PolarHBondContact O-OG 3.16Å; R13-S15 PolarHBondContact O-N 2.92Å; R13-S15 VanDerWaalsContact O-N 3.07Å; S15-P17 VanDerWaalsContact C-CD 3.45Å
16L94.4Very high81.6Confident43 Ų4363.7 Ų63.723%0.22530%0.304CS..  trans-12863.6-178.6-57.2178.2000111A11 N14 W18 M19 A141 F161A11-L16 HydrophobicContact CB-CD1 3.79Å; A11-L16 HydrophobicContact CB-CG 4.34Å; N14-L16 VanDerWaalsContact C-N 3.33Å; N14-L16 PolarHBondContact O-N 3.3Å; L16-W18 HydrophobicContact CD2-CH2 4.25Å; L16-W18 HydrophobicContact CD2-CZ2 3.6Å; L16-W18 PolarHBondContact O-N 3.4Å; L16-W18 VanDerWaalsContact O-N 3.14Å; L16-M19 HydrophobicContact CB-CG 3.85Å; L16-M19 PolarHBondContact O-N 3.47Å; L16-A141 HydrophobicContact CD1-CB 3.63Å; L16-F161 HydrophobicContact CD1-CZ 4.16Å; L16-F161 HydrophobicContact CD2-CE2 3.6Å; L16-F161 HydrophobicContact CD2-CZ 3.48Å; L16-F161 VanDerWaalsContact CD2-CZ 3.48Å; L16-F161 HydrophobicContact CG-CZ 4.48Å
17P95.4Very high81.2Confident13 Ų1364 Ų648%0.08430%0.301CS..THydrogen-bonded Turntrans-72.6-5.9-168.632.8-40.2000114.7S15 E119 I120 S121S15-P17 VanDerWaalsContact C-CD 3.45Å; P17-E119 VanDerWaalsContact CA-O 3.29Å; P17-E119 WeakPolarHBondContact CA-O 3.49Å; P17-E119 WeakPolarHBondContact CB-O 3.27Å; P17-I120 WeakPolarHBondContact O-CA 3.35Å; P17-S121 CarbonylContact C-O 3.58Å; P17-S121 VanDerWaalsContact C-O 3.3Å; P17-S121 WeakPolarHBondContact CB-OG 2.87Å; P17-S121 WeakPolarHBondContact CG-OG 3.26Å; P17-S121 PolarHBondContact O-N 2.57Å
18W96.8Very high80.6Confident19 Ų1961 Ų617%0.07229%0.293CS..THydrogen-bonded Turntrans-87.6-12.4176.647.781.5000113.6L16 A20 F35 L36 S121 I123 F161 Y168L16-W18 HydrophobicContact CD2-CH2 4.25Å; L16-W18 HydrophobicContact CD2-CZ2 3.6Å; L16-W18 PolarHBondContact O-N 3.4Å; L16-W18 VanDerWaalsContact O-N 3.14Å; W18-A20 PolarHBondContact O-N 2.8Å; W18-F35 CarbonylContact O-C 3.45Å; W18-F35 VanDerWaalsContact O-CA 3.23Å; W18-F35 WeakPolarHBondContact O-CA 3.48Å; W18-L36 PolarHBondContact O-N 2.85Å; W18-S121 WeakPolarHBondContact CA-O 3.38Å; W18-S121 VanDerWaalsContact CB-O 3.27Å; W18-S121 WeakPolarHBondContact CB-O 3.47Å; W18-S121 PolarHBondContact N-O 3.22Å; W18-S121 VanDerWaalsContact N-O 3.15Å; W18-I123 HydrophobicContact CB-CB 3.84Å; W18-I123 HydrophobicContact CB-CG2 4.19Å; W18-I123 HydrophobicContact CD2-CB 3.84Å; W18-I123 HydrophobicContact CD2-CD1 4.07Å; W18-I123 HydrophobicContact CD2-CG1 4.23Å; W18-I123 HydrophobicContact CE3-CB 4.19Å; W18-I123 HydrophobicContact CG-CB 3.67Å; W18-I123 HydrophobicContact CG-CD1 4.3Å; W18-I123 HydrophobicContact CG-CG1 4.45Å; W18-I123 HydrophobicContact CG-CG2 4.23Å; W18-I123 HydrophobicContact CZ2-CD1 4.16Å; W18-F161 AromaticContact CZ2-CD2 3.83Å; W18-F161 HydrophobicContact CZ2-CD2 3.83Å; W18-F161 AromaticContact CZ2-CE2 3.87Å; W18-F161 HydrophobicContact CZ2-CE2 3.87Å; W18-F161 HydrophobicContact CZ2-CG 4.41Å; W18-F161 HydrophobicContact CZ2-CZ 4.48Å; W18-Y168 HydrophobicContact CH2-CD1 4.44Å; W18-Y168 AromaticContact CH2-CD2 3.81Å; W18-Y168 HydrophobicContact CH2-CD2 3.81Å; W18-Y168 AromaticContact CH2-CG 3.72Å; W18-Y168 HydrophobicContact CH2-CG 3.72Å; W18-Y168 HydrophobicContact CZ2-CG 4.29Å; W18-Y168 HydrophobicContact CZ3-CD2 4.45Å
19M95.8Very high79.9Confident11 Ų1166.9 Ų66.95%0.05431%0.313CS..EExtended strand (participates in β ladder)trans-65.8133.2-174.2-68.2-65.6-64.600111.5L16 A141 W143 P159L16-M19 HydrophobicContact CB-CG 3.85Å; L16-M19 PolarHBondContact O-N 3.47Å; M19-A141 HydrophobicContact CE-CB 4.19Å; M19-A141 WeakPolarHBondContact CE-O 3.33Å; M19-A141 HydrophobicContact SD-CB 4.23Å; M19-W143 HydrophobicContact CB-CH2 3.45Å; M19-W143 VanDerWaalsContact CB-CH2 3.45Å; M19-W143 HydrophobicContact CB-CZ2 4.28Å; M19-W143 HydrophobicContact CB-CZ3 4.02Å; M19-W143 HydrophobicContact CE-CE3 4.29Å; M19-W143 HydrophobicContact CE-CH2 4.26Å; M19-W143 HydrophobicContact CE-CZ3 3.79Å; M19-W143 HydrophobicContact CG-CH2 4.44Å; M19-P159 HydrophobicContact SD-CG 3.83Å
20A96Very high79.7Confident0 Ų060.8 Ų60.80%030%0.295CS..EExtended strand (participates in β ladder)trans-121.9132.3178.700000110.1W18 A33 G34 V48 V69 L71W18-A20 PolarHBondContact O-N 2.8Å; A20-A33 CarbonylContact O-C 3.51Å; A20-G34 PolarHBondContact N-O 3.02Å; A20-G34 PolarHBondContact O-N 2.96Å; A20-V48 HydrophobicContact CB-CG1 3.85Å; A20-V48 HydrophobicContact CB-CG2 4.38Å; A20-V69 HydrophobicContact CB-CG1 4.05Å; A20-L71 HydrophobicContact CB-CD2 3.59Å; A20-L71 HydrophobicContact CB-CG 4.46Å
21Y93Very high79.8Confident35 Ų3557.8 Ų57.814%0.13728%0.277CS..EExtended strand (participates in β ladder)trans-97.5122.8170.5-176.4-91.9000109L23 S31 V69 I70 M76 W143Y21-L23 HydrophobicContact CD1-CB 4.31Å; Y21-L23 HydrophobicContact CE1-CB 4.02Å; Y21-L23 HydrophobicContact CE1-CD1 4.3Å; Y21-S31 WeakPolarHBondContact OH-CB 3.5Å; Y21-S31 PolarHBondContact OH-OG 3.02Å; Y21-V69 CarbonylContact O-C 3.48Å; Y21-V69 WeakPolarHBondContact O-CA 3.26Å; Y21-I70 HydrophobicContact CD1-CD1 4.21Å; Y21-I70 PolarHBondContact N-O 2.66Å; Y21-I70 PolarHBondContact O-N 3.05Å; Y21-M76 HydrophobicContact CD1-CE 3.31Å; Y21-M76 HydrophobicContact CD1-SD 4.37Å; Y21-M76 HydrophobicContact CD2-CE 3.77Å; Y21-M76 HydrophobicContact CD2-CG 4.16Å; Y21-M76 HydrophobicContact CD2-SD 4.04Å; Y21-M76 HydrophobicContact CE1-CE 3.55Å; Y21-M76 HydrophobicContact CE2-CE 4Å; Y21-M76 HydrophobicContact CE2-CG 4.41Å; Y21-M76 HydrophobicContact CG-CE 3.39Å; Y21-M76 HydrophobicContact CG-SD 3.86Å; Y21-W143 HydrophobicContact CD2-CD2 4.49Å; Y21-W143 HydrophobicContact CD2-CE3 4.15Å
22I92.7Very high80Confident0 Ų056.5 Ų56.50%027%0.266CS..EExtended strand (participates in β ladder)trans-102.999.6-179.5-57170000106.9I24 S31 C32 V48 T50 H68 V69 L108I22-I24 HydrophobicContact CG2-CG1 4.19Å; I22-I24 PolarHBondContact O-N 2.83Å; I22-S31 WeakPolarHBondContact O-CA 3.41Å; I22-C32 WeakPolarHBondContact CA-O 3.35Å; I22-C32 HydrophobicContact CB-CB 4.33Å; I22-C32 WeakPolarHBondContact CB-O 3.28Å; I22-C32 PolarHBondContact N-O 2.83Å; I22-C32 PolarHBondContact O-N 2.98Å; I22-V48 HydrophobicContact CD1-CG1 4.44Å; I22-T50 HydrophobicContact CD1-CG2 3.63Å; I22-T50 WeakPolarHBondContact CD1-OG1 3.35Å; I22-H68 CarbonylContact C-O 3.59Å; I22-H68 WeakPolarHBondContact CA-O 3.45Å; I22-V69 HydrophobicContact CG1-CG2 4.42Å; I22-L108 HydrophobicContact CD1-CD1 3.75Å; I22-L108 HydrophobicContact CG1-CD1 4.25Å; I22-L108 HydrophobicContact CG2-CD1 4.4Å
23L84.5Confident80.4Confident26 Ų2646.4 Ų46.414%0.13623%0.228CC..EExtended strand (participates in β ladder)trans-77.1108167.9-17868000107.5Y21 V25 E29 H68Y21-L23 HydrophobicContact CD1-CB 4.31Å; Y21-L23 HydrophobicContact CE1-CB 4.02Å; Y21-L23 HydrophobicContact CE1-CD1 4.3Å; L23-V25 VanDerWaalsContact C-N 3.34Å; L23-V25 HydrophobicContact CD2-CG2 3.75Å; L23-V25 HydrophobicContact CG-CG2 3.95Å; L23-V25 PolarHBondContact O-N 2.85Å; L23-E29 HydrophobicContact CD1-CB 4.26Å; L23-E29 HydrophobicContact CD1-CG 4.12Å; L23-H68 HydrophobicContact CB-CB 4.23Å; L23-H68 PolarHBondContact N-O 3.36Å; L23-H68 PolarHBondContact O-N 3.04Å
24I81.1Confident80.9Confident3 Ų339.1 Ų39.12%0.01520%0.201CC..EExtended strand (participates in β ladder)trans-85.694.3165-46.4166.1000102.8I22 E26 M30 C32 C54 L62 L67I22-I24 HydrophobicContact CG2-CG1 4.19Å; I22-I24 PolarHBondContact O-N 2.83Å; I24-E26 HydrophobicContact CB-CG 4.26Å; I24-E26 HydrophobicContact CG2-CG 3.48Å; I24-E26 VanDerWaalsContact CG2-CG 3.48Å; I24-E26 PolarHBondContact O-N 2.74Å; I24-M30 CarbonylContact C-O 3.48Å; I24-M30 WeakPolarHBondContact CA-O 3.33Å; I24-M30 HydrophobicContact CB-CB 4.29Å; I24-M30 WeakPolarHBondContact CB-O 3.44Å; I24-M30 HydrophobicContact CD1-CB 4.22Å; I24-M30 PolarHBondContact N-O 3.48Å; I24-C32 HydrophobicContact CD1-CB 4.5Å; I24-C54 HydrophobicContact CD1-CB 4.29Å; I24-C54 WeakPolarHBondContact CD1-O 3.48Å; I24-L62 HydrophobicContact CG2-CD1 3.37Å; I24-L67 HydrophobicContact CB-CD2 4.45Å; I24-L67 HydrophobicContact CG1-CD2 4.12Å; I24-L67 HydrophobicContact CG2-CD2 4Å
25V65.2Low81.6Confident57 Ų5735.8 Ų35.835%0.34518%0.183SC..  trans-61.698.8171168.60000102.4L23 R66 H68 R520L23-V25 VanDerWaalsContact C-N 3.34Å; L23-V25 HydrophobicContact CD2-CG2 3.75Å; L23-V25 HydrophobicContact CG-CG2 3.95Å; L23-V25 PolarHBondContact O-N 2.85Å; V25-R66 PolarHBondContact N-O 3.42Å; V25-H68 WeakPolarHBondContact CG2-CD2 3.18Å; V25-R520 PolarHBondContact O-NH1 2.83Å; V25-R520 PolarHBondContact O-NH2 2.86Å
26E56.8Low82Confident58 Ų5833.2 Ų33.227%0.27117%0.165SC..SBendtrans-110.1-153.6163.7-47.5-129.191.300108.2I24 E28 L62 R66 R520I24-E26 HydrophobicContact CB-CG 4.26Å; I24-E26 HydrophobicContact CG2-CG 3.48Å; I24-E26 VanDerWaalsContact CG2-CG 3.48Å; I24-E26 PolarHBondContact O-N 2.74Å; E26-E28 WeakPolarHBondContact CB-O 3.32Å; E26-L62 WeakPolarHBondContact OE1-CD2 3.13Å; E26-R66 IonicContact OE1-CZ 3.22Å; E26-R66 IonicContact OE1-NH2 3.09Å; E26-R66 PolarHBondContact OE1-NH2 2.89Å; E26-R520 VanDerWaalsContact CA-CZ 3.4Å; E26-R520 VanDerWaalsContact CA-NH2 3.26Å; E26-R520 IonicContact OE1-CZ 2.83Å; E26-R520 IonicContact OE1-NE 2.93Å; E26-R520 IonicContact OE1-NH2 3.82Å; E26-R520 PolarHBondContact OE1-NH2 3.04Å
27E44Very low82Confident54 Ų5431.1 Ų31.125%0.25215%0.154SC..SBendtrans-79.2-54.8176.3-68-177.216300108.2Y498 R520E27-Y498 HydrophobicContact CB-CD1 3.13Å; E27-Y498 HydrophobicContact CB-CD2 3.74Å; E27-Y498 HydrophobicContact CB-CE1 3.48Å; E27-Y498 VanDerWaalsContact CB-CE1 3.48Å; E27-Y498 HydrophobicContact CB-CE2 4.03Å; E27-Y498 HydrophobicContact CB-CG 3.28Å; E27-Y498 HydrophobicContact CG-CD1 3.2Å; E27-Y498 HydrophobicContact CG-CD2 4.39Å; E27-Y498 HydrophobicContact CG-CE1 3.97Å; E27-Y498 HydrophobicContact CG-CG 3.47Å; E27-Y498 VanDerWaalsContact CG-CG 3.47Å; E27-Y498 WeakPolarHBondContact O-CE1 3.29Å; E27-Y498 PolarHBondContact O-OH 3.16Å; E27-Y498 WeakPolarHBondContact OE1-CA 3.29Å; E27-Y498 VanDerWaalsContact OE1-CB 3.31Å; E27-Y498 WeakPolarHBondContact OE1-CB 3.42Å; E27-Y498 VanDerWaalsContact OE2-CB 3.25Å; E27-Y498 WeakPolarHBondContact OE2-CB 3.27Å; E27-R520 HydrophobicContact CG-CG 3.95Å; E27-R520 WeakPolarHBondContact OE1-CA 3.26Å; E27-R520 PolarHBondContact OE1-N 3.25Å
28E46.1Very low81.7Confident116 Ų11634 Ų3454%0.54217%0.169SC..SBendtrans-80.6134.8154.9-66-170.3162.500109.8E26 M30E26-E28 WeakPolarHBondContact CB-O 3.32Å; E28-M30 VanDerWaalsContact C-N 3.27Å; E28-M30 PolarHBondContact O-N 3.07Å
29E51.3Low81.1Confident151 Ų15134.8 Ų34.871%0.70617%0.174SC*.  trans-62.792.5170-77.1-170.9161.700109.3L23L23-E29 HydrophobicContact CD1-CB 4.26Å; L23-E29 HydrophobicContact CD1-CG 4.12Å
30M71.1Confident80.1Confident77 Ų7737.4 Ų37.438%0.37920%0.204SC..EExtended strand (participates in β ladder)trans-81.3135.9166.2-70.1-169.570.600108.3I24 E28I24-M30 CarbonylContact C-O 3.48Å; I24-M30 WeakPolarHBondContact CA-O 3.33Å; I24-M30 HydrophobicContact CB-CB 4.29Å; I24-M30 WeakPolarHBondContact CB-O 3.44Å; I24-M30 HydrophobicContact CD1-CB 4.22Å; I24-M30 PolarHBondContact N-O 3.48Å; E28-M30 VanDerWaalsContact C-N 3.27Å; E28-M30 PolarHBondContact O-N 3.07Å
31S82.4Confident79Confident27 Ų2740.5 Ų40.519%0.18923%0.225CC..EExtended strand (participates in β ladder)trans-124.8138.2174.563.10000110.3Y21 I22 G154Y21-S31 WeakPolarHBondContact OH-CB 3.5Å; Y21-S31 PolarHBondContact OH-OG 3.02Å; I22-S31 WeakPolarHBondContact O-CA 3.41Å; S31-G154 VanDerWaalsContact O-CA 3.26Å; S31-G154 WeakPolarHBondContact O-CA 3.34Å
32C91.4Very high78.4Confident7 Ų741.3 Ų41.35%0.04724%0.244CC..EExtended strand (participates in β ladder)trans-117.8163.6165.5-77.70000109.6I22 I24 C54 G154 S156I22-C32 WeakPolarHBondContact CA-O 3.35Å; I22-C32 HydrophobicContact CB-CB 4.33Å; I22-C32 WeakPolarHBondContact CB-O 3.28Å; I22-C32 PolarHBondContact N-O 2.83Å; I22-C32 PolarHBondContact O-N 2.98Å; I24-C32 HydrophobicContact CD1-CB 4.5Å; C32-C54 HydrophobicContact CB-CB 3.76Å; C32-C54 WeakPolarHBondContact CB-SG 3.47Å; C32-C54 WeakPolarHBondContact SG-CB 3.46Å; C32-C54 CovalentContact SG-SG 2.03Å; C32-C54 PolarHBondContact SG-SG 3.47Å; C32-G154 CarbonylContact C-O 3.58Å; C32-S156 WeakPolarHBondContact CB-O 3.44Å
33A92.6Very high78.1Confident0 Ų046.6 Ų46.60%027%0.273CS..EExtended strand (participates in β ladder)trans-95.7161.7168.700000110.4A20 T50 G154 S156 G157A20-A33 CarbonylContact O-C 3.51Å; A33-T50 PolarHBondContact O-OG1 3.19Å; A33-G154 PolarHBondContact N-O 2.92Å; A33-S156 PolarHBondContact N-O 3Å; A33-S156 VanDerWaalsContact O-O 3.12Å; A33-G157 CarbonylContact O-C 3.6Å; A33-G157 VanDerWaalsContact O-C 3.31Å; A33-G157 WeakPolarHBondContact O-CA 3.25Å
34G95.7Very high78.4Confident0 Ų048.4 Ų48.40%028%0.28CS..EExtended strand (participates in β ladder)trans-158.7-175.6170.300000110A20 I49A20-G34 PolarHBondContact N-O 3.02Å; A20-G34 PolarHBondContact O-N 2.96Å; G34-I49 CarbonylContact C-O 3.46Å; G34-I49 WeakPolarHBondContact CA-O 3.38Å
35F97.5Very high79Confident0 Ų048.2 Ų48.20%028%0.28CS..EExtended strand (participates in β ladder)trans-146.3141.8177.452.2-84.3000112.6W18 V37 V48 I49 I123 P159 A170 V173 M194W18-F35 CarbonylContact O-C 3.45Å; W18-F35 VanDerWaalsContact O-CA 3.23Å; W18-F35 WeakPolarHBondContact O-CA 3.48Å; F35-V37 HydrophobicContact CD2-CG1 3.75Å; F35-V37 HydrophobicContact CE2-CG1 3.82Å; F35-V48 WeakPolarHBondContact O-CA 3.4Å; F35-I49 HydrophobicContact CD2-CB 4.41Å; F35-I49 HydrophobicContact CE1-CB 4.27Å; F35-I49 HydrophobicContact CE1-CG2 4.21Å; F35-I49 HydrophobicContact CE2-CB 3.89Å; F35-I49 HydrophobicContact CE2-CD1 4.28Å; F35-I49 HydrophobicContact CE2-CG1 4.49Å; F35-I49 HydrophobicContact CE2-CG2 4.29Å; F35-I49 HydrophobicContact CZ-CB 3.82Å; F35-I49 HydrophobicContact CZ-CG2 3.76Å; F35-I49 PolarHBondContact N-O 2.88Å; F35-I49 PolarHBondContact O-N 3.11Å; F35-I123 HydrophobicContact CB-CG2 4.4Å; F35-I123 HydrophobicContact CD2-CG2 3.58Å; F35-I123 HydrophobicContact CE2-CG2 4.29Å; F35-I123 HydrophobicContact CG-CG2 4.35Å; F35-P159 HydrophobicContact CB-CB 4.4Å; F35-P159 HydrophobicContact CB-CG 4.01Å; F35-P159 HydrophobicContact CD1-CB 3.52Å; F35-P159 HydrophobicContact CD1-CG 3.8Å; F35-P159 HydrophobicContact CE1-CB 3.8Å; F35-P159 HydrophobicContact CG-CB 3.89Å; F35-P159 HydrophobicContact CG-CG 4.04Å; F35-P159 HydrophobicContact CZ-CB 4.4Å; F35-A170 HydrophobicContact CD2-CB 4.08Å; F35-A170 HydrophobicContact CE2-CB 3.6Å; F35-A170 HydrophobicContact CZ-CB 4.02Å; F35-V173 HydrophobicContact CE1-CG2 3.95Å; F35-V173 HydrophobicContact CZ-CG2 3.9Å; F35-M194 HydrophobicContact CE2-CE 4.06Å; F35-M194 HydrophobicContact CZ-CE 3.93Å; F35-M194 HydrophobicContact CZ-SD 4.34Å
36L97.5Very high80.3Confident0 Ų046.2 Ų46.20%027%0.267CS..EExtended strand (participates in β ladder)trans-74.3129.7177.5-17175000109.9W18 I47 V48 L71 Y116 I120 P122 I123W18-L36 PolarHBondContact O-N 2.85Å; L36-I47 WeakPolarHBondContact CD1-O 3.38Å; L36-V48 HydrophobicContact CD1-CG2 3.99Å; L36-L71 HydrophobicContact CB-CD2 4.16Å; L36-L71 HydrophobicContact CD1-CD1 4.3Å; L36-Y116 HydrophobicContact CD2-CE1 4.48Å; L36-I120 HydrophobicContact CD2-CG2 3.86Å; L36-P122 HydrophobicContact CD2-CB 4.42Å; L36-P122 HydrophobicContact CG-CB 4.31Å; L36-P122 VanDerWaalsContact O-CA 3.25Å; L36-P122 WeakPolarHBondContact O-CA 3.34Å; L36-I123 PolarHBondContact O-N 2.96Å
37V95.2Very high82.2Confident0 Ų043.4 Ų43.40%025%0.254CS..EExtended strand (participates in β ladder)trans-117.9149.9175.7-64.10000110.5F35 S45 I47 I49 P122 I123 L125 M205F35-V37 HydrophobicContact CD2-CG1 3.75Å; F35-V37 HydrophobicContact CE2-CG1 3.82Å; V37-S45 WeakPolarHBondContact O-CB 3.34Å; V37-S45 PolarHBondContact O-OG 3.49Å; V37-I47 HydrophobicContact CG2-CB 3.92Å; V37-I47 HydrophobicContact CG2-CG2 3.59Å; V37-I47 PolarHBondContact N-O 3.15Å; V37-I47 VanDerWaalsContact N-O 3.09Å; V37-I49 HydrophobicContact CG1-CD1 3.85Å; V37-I49 HydrophobicContact CG1-CG1 4.2Å; V37-I49 HydrophobicContact CG2-CD1 4.04Å; V37-I49 HydrophobicContact CG2-CG1 4.09Å; V37-P122 VanDerWaalsContact C-CB 3.49Å; V37-I123 HydrophobicContact CG1-CG2 4.34Å; V37-L125 HydrophobicContact CB-CD2 4.34Å; V37-L125 HydrophobicContact CG1-CD2 3.87Å; V37-L125 HydrophobicContact CG1-CG 4.48Å; V37-M205 HydrophobicContact CG2-CE 4.15Å
38D89.9Confident84.7Confident74 Ų7440.9 Ų40.940%0.39624%0.242SC..  trans-73.6130.4178.7-1728.4000110G40 Y116 P122 M205D38-G40 PolarHBondContact OD1-N 3Å; D38-Y116 PolarHBondContact OD1-OH 2.96Å; D38-P122 HydrophobicContact CB-CB 4.03Å; D38-P122 HydrophobicContact CB-CG 3.78Å; D38-P122 VanDerWaalsContact N-CB 3.29Å; D38-M205 WeakPolarHBondContact O-CE 3.47Å
39N83Confident87.1Confident35 Ų3535.3 Ų35.319%0.18722%0.216CC..  trans-100.17.9176.871.63.2000113.4S41 Q44 D46 I47 M205N39-S41 VanDerWaalsContact C-N 3.29Å; N39-S41 VanDerWaalsContact CG-OG 3.27Å; N39-S41 PolarHBondContact ND2-OG 3.11Å; N39-S41 PolarHBondContact O-N 2.92Å; N39-S41 WeakPolarHBondContact OD1-CB 3.33Å; N39-S41 PolarHBondContact OD1-N 2.92Å; N39-S41 PolarHBondContact OD1-OG 2.69Å; N39-Q44 PolarHBondContact OD1-O 3.27Å; N39-D46 PolarHBondContact ND2-OD1 3.22Å; N39-I47 HydrophobicContact CB-CG1 3.89Å; N39-M205 HydrophobicContact CB-CE 3.38Å
40G76Confident89.2Confident66 Ų6628.1 Ų28.168%0.6818%0.182SC*.SBendtrans78.88.3179.600000114.1D38 G42D38-G40 PolarHBondContact OD1-N 3Å; G40-G42 PolarHBondContact O-N 2.77Å
41S72.8Confident90.2Very high64 Ų6424.5 Ų24.545%0.44816%0.164SC..SBendtrans-83.117.9-177.7-54.60000114.3N39N39-S41 VanDerWaalsContact C-N 3.29Å; N39-S41 VanDerWaalsContact CG-OG 3.27Å; N39-S41 PolarHBondContact ND2-OG 3.11Å; N39-S41 PolarHBondContact O-N 2.92Å; N39-S41 WeakPolarHBondContact OD1-CB 3.33Å; N39-S41 PolarHBondContact OD1-N 2.92Å; N39-S41 PolarHBondContact OD1-OG 2.69Å
42G78.9Confident90.5Very high52 Ų5223.2 Ų23.254%0.53616%0.155SC..SBendtrans91-125.2-179.200000112.4G40 Q44 Y116G40-G42 PolarHBondContact O-N 2.77Å; G42-Q44 VanDerWaalsContact C-N 3.29Å; G42-Q44 PolarHBondContact O-N 2.89Å; G42-Y116 WeakPolarHBondContact O-CE2 3.43Å
43N87.7Confident90.3Very high111 Ų11126.1 Ų26.159%0.59417%0.168SC*.SBendtrans-91.126.5-17568.7-24.9000114Y116N43-Y116 HydrophobicContact CB-CD2 4.37Å; N43-Y116 PolarHBondContact O-N 2.76Å
44Q91.3Very high90Very high64 Ų6426.5 Ų26.530%0.29917%0.171SC..EExtended strand (participates in β ladder)trans-152.3150.9-179.561.9179.8-2.700110.8N39 G42 P113 V114 Y116N39-Q44 PolarHBondContact OD1-O 3.27Å; G42-Q44 VanDerWaalsContact C-N 3.29Å; G42-Q44 PolarHBondContact O-N 2.89Å; Q44-P113 HydrophobicContact CB-CB 4.04Å; Q44-P113 HydrophobicContact CG-CB 4.03Å; Q44-V114 CarbonylContact C-O 3.51Å; Q44-V114 WeakPolarHBondContact CA-O 3.35Å; Q44-V114 WeakPolarHBondContact CB-O 3.36Å; Q44-Y116 VanDerWaalsContact C-CZ 3.49Å; Q44-Y116 PolarHBondContact O-OH 2.96Å
45S93.2Very high89.3Confident0 Ų026.6 Ų26.60%017%0.171CC..EExtended strand (participates in β ladder)trans-139.2154.4173179.70000111.7V37 I47 P113 V114 Y116V37-S45 WeakPolarHBondContact O-CB 3.34Å; V37-S45 PolarHBondContact O-OG 3.49Å; S45-I47 PolarHBondContact OG-N 3.23Å; S45-P113 CarbonylContact O-C 3.59Å; S45-P113 WeakPolarHBondContact O-CA 3.3Å; S45-V114 PolarHBondContact N-O 2.77Å; S45-V114 PolarHBondContact O-N 3.33Å; S45-Y116 WeakPolarHBondContact CB-OH 3.48Å
46D92.7Very high88Confident14 Ų1426.9 Ų26.98%0.07517%0.173CC..EExtended strand (participates in β ladder)trans-128.819174.66010.9000113.3N39 K109 L110 P113N39-D46 PolarHBondContact ND2-OD1 3.22Å; D46-K109 HydrophobicContact CB-CD 4.47Å; D46-K109 VanDerWaalsContact CG-CE 3.44Å; D46-K109 IonicContact OD1-NZ 3.3Å; D46-K109 PolarHBondContact OD1-NZ 2.91Å; D46-K109 WeakPolarHBondContact OD2-CE 3.49Å; D46-K109 IonicContact OD2-NZ 3.85Å; D46-K109 PolarHBondContact OD2-NZ 3.16Å; D46-L110 HydrophobicContact CB-CB 4.1Å; D46-L110 WeakPolarHBondContact O-CG 3.42Å; D46-L110 PolarHBondContact O-N 2.89Å; D46-P113 HydrophobicContact CB-CB 4.24Å; D46-P113 HydrophobicContact CB-CG 4.09Å
47I95.3Very high86.5Confident0 Ų029.3 Ų29.30%019%0.191CC..EExtended strand (participates in β ladder)trans-115.9123.9-178.5-55.1-63.4000110.4L36 V37 N39 S45 L107 L108 K109 M205 I208L36-I47 WeakPolarHBondContact CD1-O 3.38Å; V37-I47 HydrophobicContact CG2-CB 3.92Å; V37-I47 HydrophobicContact CG2-CG2 3.59Å; V37-I47 PolarHBondContact N-O 3.15Å; V37-I47 VanDerWaalsContact N-O 3.09Å; N39-I47 HydrophobicContact CB-CG1 3.89Å; S45-I47 PolarHBondContact OG-N 3.23Å; I47-L107 HydrophobicContact CG2-CD2 4.32Å; I47-L107 HydrophobicContact CG2-CG 4.24Å; I47-L108 WeakPolarHBondContact CA-O 3.38Å; I47-K109 HydrophobicContact CD1-CD 3.49Å; I47-K109 VanDerWaalsContact CD1-CD 3.49Å; I47-M205 HydrophobicContact CB-CE 4.02Å; I47-M205 HydrophobicContact CG1-CE 3.8Å; I47-M205 HydrophobicContact CG1-CG 4.21Å; I47-M205 HydrophobicContact CG2-CE 4.1Å; I47-M205 HydrophobicContact CG2-CG 4.08Å; I47-M205 HydrophobicContact CG2-SD 4.44Å; I47-I208 HydrophobicContact CD1-CG2 4.25Å
48V97Very high84.4Confident0 Ų037.1 Ų37.10%022%0.22CC..EExtended strand (participates in β ladder)trans-118.8137.5172.8172.30000109.1A20 I22 F35 L36 V69 L108 L110A20-V48 HydrophobicContact CB-CG1 3.85Å; A20-V48 HydrophobicContact CB-CG2 4.38Å; I22-V48 HydrophobicContact CD1-CG1 4.44Å; F35-V48 WeakPolarHBondContact O-CA 3.4Å; L36-V48 HydrophobicContact CD1-CG2 3.99Å; V48-V69 HydrophobicContact CG2-CG1 4.2Å; V48-L108 HydrophobicContact CB-CB 4.27Å; V48-L108 PolarHBondContact N-O 2.78Å; V48-L108 PolarHBondContact O-N 2.83Å; V48-L110 HydrophobicContact CG2-CD1 4.2Å; V48-L110 HydrophobicContact CG2-CD2 4.24Å; V48-L110 HydrophobicContact CG2-CG 4.4Å
49I97Very high82.6Confident0 Ų040 Ų400%024%0.24CC..EExtended strand (participates in β ladder)trans-104.7139.6175.5-60.8-176.7000109.3G34 F35 V37 I105 L107 L125 V173 M194 I201G34-I49 CarbonylContact C-O 3.46Å; G34-I49 WeakPolarHBondContact CA-O 3.38Å; F35-I49 HydrophobicContact CD2-CB 4.41Å; F35-I49 HydrophobicContact CE1-CB 4.27Å; F35-I49 HydrophobicContact CE1-CG2 4.21Å; F35-I49 HydrophobicContact CE2-CB 3.89Å; F35-I49 HydrophobicContact CE2-CD1 4.28Å; F35-I49 HydrophobicContact CE2-CG1 4.49Å; F35-I49 HydrophobicContact CE2-CG2 4.29Å; F35-I49 HydrophobicContact CZ-CB 3.82Å; F35-I49 HydrophobicContact CZ-CG2 3.76Å; F35-I49 PolarHBondContact N-O 2.88Å; F35-I49 PolarHBondContact O-N 3.11Å; V37-I49 HydrophobicContact CG1-CD1 3.85Å; V37-I49 HydrophobicContact CG1-CG1 4.2Å; V37-I49 HydrophobicContact CG2-CD1 4.04Å; V37-I49 HydrophobicContact CG2-CG1 4.09Å; I49-I105 HydrophobicContact CG2-CD1 4.02Å; I49-I105 HydrophobicContact CG2-CG1 3.9Å; I49-L107 HydrophobicContact CD1-CD1 4.22Å; I49-L107 HydrophobicContact CG1-CD1 3.99Å; I49-L107 HydrophobicContact CG1-CG 4.12Å; I49-L125 HydrophobicContact CD1-CD2 4.1Å; I49-V173 HydrophobicContact CG2-CG2 4Å; I49-M194 HydrophobicContact CD1-CE 3.7Å; I49-M194 HydrophobicContact CG2-CE 4.42Å; I49-I201 HydrophobicContact CD1-CD1 4.06Å; I49-I201 HydrophobicContact CD1-CG1 4.37Å; I49-I201 HydrophobicContact CD1-CG2 4.14Å
50T95.3Very high81.4Confident0 Ų044 Ų440%026%0.258CS..EExtended strand (participates in β ladder)trans-150.7-177.8175.7-170.50000110.7I22 A33 I55 T106 L108I22-T50 HydrophobicContact CD1-CG2 3.63Å; I22-T50 WeakPolarHBondContact CD1-OG1 3.35Å; A33-T50 PolarHBondContact O-OG1 3.19Å; T50-I55 HydrophobicContact CG2-CD1 3.54Å; T50-T106 PolarHBondContact N-O 2.79Å; T50-T106 PolarHBondContact O-N 3.31Å; T50-L108 HydrophobicContact CG2-CD1 4.08Å; T50-L108 HydrophobicContact CG2-CG 4.16Å
51A91.9Very high81.1Confident0 Ų045 Ų450%025%0.248CC..  trans-77.4148.4175.300000111.6C54 V173A51-C54 WeakPolarHBondContact O-CB 3.36Å; A51-V173 HydrophobicContact CB-CG1 4.43Å
52T89.2Confident81.1Confident0 Ų042.7 Ų42.70%023%0.23CC..SBendtrans-70.6-38177.4-61.20000112C54 I55 A56 T93 Y96 D104 I105 T106T52-C54 PolarHBondContact O-N 3.08Å; T52-I55 PolarHBondContact O-N 3.36Å; T52-A56 HydrophobicContact CG2-CB 3.83Å; T52-A56 PolarHBondContact O-N 3.27Å; T52-T93 HydrophobicContact CG2-CG2 4.07Å; T52-Y96 HydrophobicContact CG2-CD1 3.89Å; T52-Y96 HydrophobicContact CG2-CG 3.8Å; T52-D104 WeakPolarHBondContact CA-OD1 3.28Å; T52-D104 WeakPolarHBondContact CB-OD1 3.36Å; T52-D104 PolarHBondContact N-OD1 3.1Å; T52-I105 PolarHBondContact OG1-N 2.98Å; T52-I105 PolarHBondContact OG1-O 3.34Å; T52-T106 VanDerWaalsContact CA-OG1 3.28Å; T52-T106 WeakPolarHBondContact CA-OG1 3.04Å; T52-T106 WeakPolarHBondContact CB-OG1 3.19Å; T52-T106 PolarHBondContact OG1-OG1 2.86Å
53H85.9Confident81.1Confident68 Ų6842.3 Ų42.332%0.31522%0.222SC..THydrogen-bonded Turntrans-61.7-18.9179.577-102.2000113.3I55 Y96 D104 S156 S175H53-I55 VanDerWaalsContact C-N 3.25Å; H53-I55 PolarHBondContact O-N 3.34Å; H53-Y96 HydrophobicContact CB-CE1 4.46Å; H53-D104 IonicContact CE1-OD2 3.17Å; H53-D104 IonicContact CG-OD1 2.9Å; H53-D104 IonicContact CG-OD2 2.97Å; H53-D104 PolarHBondContact N-OD1 2.92Å; H53-D104 IonicContact ND1-OD1 2.78Å; H53-D104 PolarHBondContact ND1-OD1 2.95Å; H53-D104 IonicContact ND1-OD2 3.5Å; H53-D104 PolarHBondContact ND1-OD2 2.98Å; H53-S156 VanDerWaalsContact CE1-CB 3.49Å; H53-S156 WeakPolarHBondContact CE1-CB 3.5Å; H53-S156 PolarHBondContact CE1-OG 2.61Å; H53-S156 WeakPolarHBondContact NE2-CB 3.42Å; H53-S156 PolarHBondContact NE2-OG 2.95Å; H53-S175 PolarHBondContact CE1-O 2.83Å
54C86.3Confident80.8Confident8 Ų838.8 Ų38.85%0.05421%0.205CC..THydrogen-bonded Turntrans-69.7-20.9171.9-69.50000113.4I24 C32 A51 T52I24-C54 HydrophobicContact CD1-CB 4.29Å; I24-C54 WeakPolarHBondContact CD1-O 3.48Å; C32-C54 HydrophobicContact CB-CB 3.76Å; C32-C54 WeakPolarHBondContact CB-SG 3.47Å; C32-C54 WeakPolarHBondContact SG-CB 3.46Å; C32-C54 CovalentContact SG-SG 2.03Å; C32-C54 PolarHBondContact SG-SG 3.47Å; A51-C54 WeakPolarHBondContact O-CB 3.36Å; T52-C54 PolarHBondContact O-N 3.08Å
55I81.7Confident80.1Confident3 Ų340 Ų402%0.01522%0.22CC..THydrogen-bonded Turntrans-125.7-27.4-168.1-61.2157.2000112T50 T52 H53 L62 L67 Y91 T106 L108T50-I55 HydrophobicContact CG2-CD1 3.54Å; T52-I55 PolarHBondContact O-N 3.36Å; H53-I55 VanDerWaalsContact C-N 3.25Å; H53-I55 PolarHBondContact O-N 3.34Å; I55-L62 HydrophobicContact CG2-CB 4.5Å; I55-L62 WeakPolarHBondContact O-CG 3.31Å; I55-L62 PolarHBondContact O-N 3.05Å; I55-L67 HydrophobicContact CD1-CD1 4.43Å; I55-L67 HydrophobicContact CG1-CD1 4.06Å; I55-L67 HydrophobicContact CG1-CD2 4.28Å; I55-L67 HydrophobicContact CG2-CD1 3.91Å; I55-Y91 HydrophobicContact CG2-CD1 4.11Å; I55-Y91 HydrophobicContact CG2-CD2 3.99Å; I55-Y91 HydrophobicContact CG2-CE1 3.87Å; I55-Y91 HydrophobicContact CG2-CE2 3.76Å; I55-Y91 HydrophobicContact CG2-CG 4.17Å; I55-T106 HydrophobicContact CD1-CG2 3.44Å; I55-T106 VanDerWaalsContact CD1-CG2 3.44Å; I55-L108 HydrophobicContact CD1-CD1 4.49Å; I55-L108 HydrophobicContact CD1-CD2 3.48Å; I55-L108 VanDerWaalsContact CD1-CD2 3.48Å; I55-L108 HydrophobicContact CD1-CG 4.22Å
56A71.3Confident79.4Confident5 Ų542.4 Ų42.44%0.04123%0.23CC..BIsolated β-bridgetrans-131.7130.3-173.200000111.1T52 N61 Y98T52-A56 HydrophobicContact CG2-CB 3.83Å; T52-A56 PolarHBondContact O-N 3.27Å; A56-N61 WeakPolarHBondContact CB-OD1 3.35Å; A56-Y98 VanDerWaalsContact C-OH 3.26Å; A56-Y98 WeakPolarHBondContact CB-OH 3.46Å; A56-Y98 PolarHBondContact O-OH 3.44Å
57S64.7Low79Confident52 Ų5241.7 Ų41.736%0.36423%0.226SC..  trans-114.7168.8174.372.30000110.8T59 E60 Y98S57-T59 PolarHBondContact O-N 2.81Å; S57-T59 PolarHBondContact OG-N 2.78Å; S57-T59 PolarHBondContact OG-OG1 2.74Å; S57-E60 PolarHBondContact N-O 2.83Å; S57-E60 PolarHBondContact OG-N 2.88Å; S57-E60 PolarHBondContact OG-O 3.49Å; S57-Y98 VanDerWaalsContact C-OH 3.24Å; S57-Y98 PolarHBondContact N-OH 2.88Å; S57-Y98 PolarHBondContact O-OH 3.21Å
58R52.3Low78.7Confident164 Ų16442.7 Ų42.762%0.61923%0.231SC*.SBendtrans-55-25.8176.3-77.5-173.3-174.3-138.8-4.7113.2Y98 D99R58-Y98 HydrophobicContact CB-CD1 4.43Å; R58-Y98 HydrophobicContact CB-CG 4.48Å; R58-Y98 HydrophobicContact CG-CD1 3.54Å; R58-Y98 HydrophobicContact CG-CD2 3.92Å; R58-Y98 HydrophobicContact CG-CE1 4.2Å; R58-Y98 HydrophobicContact CG-CG 3.39Å; R58-Y98 VanDerWaalsContact N-CE1 3.28Å; R58-Y98 VanDerWaalsContact NH2-C 3.29Å; R58-Y98 PolarHBondContact NH2-O 2.75Å; R58-D99 IonicContact CZ-OD1 2.72Å; R58-D99 IonicContact NH1-OD1 2.77Å; R58-D99 PolarHBondContact NH1-OD1 2.95Å; R58-D99 IonicContact NH2-OD1 2.69Å; R58-D99 PolarHBondContact NH2-OD1 2.98Å
59T50.6Low78.5Confident134 Ų13442.7 Ų42.782%0.82223%0.231SC*.SBendtrans-106.4-31.2-170.847.50000113.4S57S57-T59 PolarHBondContact O-N 2.81Å; S57-T59 PolarHBondContact OG-N 2.78Å; S57-T59 PolarHBondContact OG-OG1 2.74Å
60E59.4Low78.3Confident118 Ų11844.1 Ų44.155%0.55124%0.238SC*.  trans-155.6145.3-173.9-165.7176.6176.200112.5S57S57-E60 PolarHBondContact N-O 2.83Å; S57-E60 PolarHBondContact OG-N 2.88Å; S57-E60 PolarHBondContact OG-O 3.49Å
61N69Low78.3Confident87 Ų8744.1 Ų44.147%0.46524%0.238SC..BIsolated β-bridgetrans-104.1134.1170.4-65.3-16.7000109.9A56 Y91A56-N61 WeakPolarHBondContact CB-OD1 3.35Å; N61-Y91 WeakPolarHBondContact CB-OH 3.48Å
62L73.5Confident78.3Confident17 Ų1744.6 Ų44.69%0.08924%0.242CC..  trans-68.5134.4-179-61.8179.5000111.5I24 E26 I55 R66 L67 Y91I24-L62 HydrophobicContact CG2-CD1 3.37Å; E26-L62 WeakPolarHBondContact OE1-CD2 3.13Å; I55-L62 HydrophobicContact CG2-CB 4.5Å; I55-L62 WeakPolarHBondContact O-CG 3.31Å; I55-L62 PolarHBondContact O-N 3.05Å; L62-R66 VanDerWaalsContact CD2-NH2 3.33Å; L62-L67 HydrophobicContact CD1-CD2 4.15Å; L62-Y91 WeakPolarHBondContact O-CE1 3.47Å; L62-Y91 VanDerWaalsContact O-CZ 3.22Å; L62-Y91 PolarHBondContact O-OH 3.4Å
63A77.9Confident78.3Confident44 Ų4445.3 Ų45.336%0.36425%0.249SC..  trans-62141.2172.900000111.3S65 R66A63-S65 PolarHBondContact O-N 2.85Å; A63-R66 HydrophobicContact CB-CG 4.26Å; A63-R66 VanDerWaalsContact O-CB 3.27Å; A63-R66 WeakPolarHBondContact O-CB 3.36Å; A63-R66 PolarHBondContact O-N 3.46Å
64P80.7Confident78.4Confident36 Ų3644.2 Ų44.223%0.23424%0.244CC..G310 helixtrans-54.2-31.2-179.8-27.433.5000114.5R66 L67 V88 Y91P64-R66 PolarHBondContact O-N 2.9Å; P64-R66 VanDerWaalsContact O-N 3.15Å; P64-L67 PolarHBondContact O-N 3.14Å; P64-L67 VanDerWaalsContact O-N 3.16Å; P64-V88 CarbonylContact C-O 3.57Å; P64-V88 HydrophobicContact CB-CG1 4.27Å; P64-Y91 HydrophobicContact CB-CD1 4.45Å; P64-Y91 HydrophobicContact CG-CD1 3.98Å; P64-Y91 HydrophobicContact CG-CE1 3.83Å
65S76.5Confident78.1Confident89 Ų8945.9 Ų45.962%0.62225%0.251SS*.G310 helixtrans-64-15.6177.357.30000114.4A63A63-S65 PolarHBondContact O-N 2.85Å
66R79.1Confident78Confident51 Ų5148.3 Ų48.319%0.19226%0.262CS..G310 helixtrans-88-10.9179.4-61.3172.354.8148.91.1112.7V25 E26 L62 A63 P64 R520V25-R66 PolarHBondContact N-O 3.42Å; E26-R66 IonicContact OE1-CZ 3.22Å; E26-R66 IonicContact OE1-NH2 3.09Å; E26-R66 PolarHBondContact OE1-NH2 2.89Å; L62-R66 VanDerWaalsContact CD2-NH2 3.33Å; A63-R66 HydrophobicContact CB-CG 4.26Å; A63-R66 VanDerWaalsContact O-CB 3.27Å; A63-R66 WeakPolarHBondContact O-CB 3.36Å; A63-R66 PolarHBondContact O-N 3.46Å; P64-R66 PolarHBondContact O-N 2.9Å; P64-R66 VanDerWaalsContact O-N 3.15Å; R66-R520 VanDerWaalsContact CB-NH1 3.28Å
67L85.6Confident78.1Confident0 Ų057.9 Ų57.90%030%0.298CS..EExtended strand (participates in β ladder)trans-106.4127.7-173.1-59.7171.9000110.9I24 I55 L62 P64 V88 Y91 L108I24-L67 HydrophobicContact CB-CD2 4.45Å; I24-L67 HydrophobicContact CG1-CD2 4.12Å; I24-L67 HydrophobicContact CG2-CD2 4Å; I55-L67 HydrophobicContact CD1-CD1 4.43Å; I55-L67 HydrophobicContact CG1-CD1 4.06Å; I55-L67 HydrophobicContact CG1-CD2 4.28Å; I55-L67 HydrophobicContact CG2-CD1 3.91Å; L62-L67 HydrophobicContact CD1-CD2 4.15Å; P64-L67 PolarHBondContact O-N 3.14Å; P64-L67 VanDerWaalsContact O-N 3.16Å; L67-V88 HydrophobicContact CB-CB 3.82Å; L67-V88 HydrophobicContact CB-CG2 3.48Å; L67-V88 VanDerWaalsContact CB-CG2 3.48Å; L67-V88 HydrophobicContact CD1-CB 4.48Å; L67-V88 HydrophobicContact CD1-CG1 4.38Å; L67-V88 HydrophobicContact CD1-CG2 4.39Å; L67-V88 PolarHBondContact O-N 2.98Å; L67-Y91 HydrophobicContact CD1-CD1 3.96Å; L67-Y91 HydrophobicContact CD1-CE1 4.25Å; L67-L108 HydrophobicContact CD1-CD2 4.04Å
68H87.7Confident78.4Confident21 Ų2159.9 Ų59.910%0.09730%0.304CS..EExtended strand (participates in β ladder)trans-128.4133.1-177.7-60.4-83.2000110.4I22 L23 V25 Y85I22-H68 CarbonylContact C-O 3.59Å; I22-H68 WeakPolarHBondContact CA-O 3.45Å; L23-H68 HydrophobicContact CB-CB 4.23Å; L23-H68 PolarHBondContact N-O 3.36Å; L23-H68 PolarHBondContact O-N 3.04Å; V25-H68 WeakPolarHBondContact CG2-CD2 3.18Å; H68-Y85 HydrophobicContact CB-CE2 3.7Å; H68-Y85 PolarHBondContact CE1-OH 3.41Å; H68-Y85 AromaticContact CG-CE2 3.95Å; H68-Y85 AromaticContact CG-CZ 3.97Å; H68-Y85 AromaticContact ND1-CE2 3.72Å; H68-Y85 AromaticContact ND1-CZ 3.26Å; H68-Y85 VanDerWaalsContact ND1-CZ 3.26Å; H68-Y85 PolarHBondContact ND1-OH 2.73Å
69V94.1Very high79.5Confident0 Ų060.1 Ų60.10%032%0.316CS..EExtended strand (participates in β ladder)trans-114.9129.1-176.6-179.70000109.3A20 Y21 I22 V48 L71 Y85 R86 V88 L108 L110A20-V69 HydrophobicContact CB-CG1 4.05Å; Y21-V69 CarbonylContact O-C 3.48Å; Y21-V69 WeakPolarHBondContact O-CA 3.26Å; I22-V69 HydrophobicContact CG1-CG2 4.42Å; V48-V69 HydrophobicContact CG2-CG1 4.2Å; V69-L71 HydrophobicContact CG1-CD1 4.45Å; V69-L71 HydrophobicContact CG1-CG 4.15Å; V69-Y85 CarbonylContact O-C 3.58Å; V69-Y85 WeakPolarHBondContact O-CA 3.43Å; V69-R86 PolarHBondContact N-O 2.93Å; V69-R86 PolarHBondContact O-N 3.11Å; V69-V88 HydrophobicContact CG2-CG2 3.99Å; V69-L108 HydrophobicContact CG2-CD1 4.15Å; V69-L110 HydrophobicContact CB-CD2 3.8Å; V69-L110 HydrophobicContact CG1-CD2 4.14Å; V69-L110 HydrophobicContact CG2-CD2 3.66Å
70I92.4Very high80.8Confident30 Ų3054.7 Ų54.715%0.15428%0.281CS..EExtended strand (participates in β ladder)trans-113.7127.3173.5-57.3169.7000107.8Y21 A73 M76 M83 Y85Y21-I70 HydrophobicContact CD1-CD1 4.21Å; Y21-I70 PolarHBondContact N-O 2.66Å; Y21-I70 PolarHBondContact O-N 3.05Å; I70-A73 HydrophobicContact CG2-CB 4.32Å; I70-M76 HydrophobicContact CD1-CE 4.11Å; I70-M83 HydrophobicContact CG2-CB 4.41Å; I70-M83 HydrophobicContact CG2-CG 4.41Å; I70-M83 HydrophobicContact CG2-SD 4.44Å; I70-Y85 HydrophobicContact CG1-CD2 4.1Å
71L94.5Very high81.7Confident0 Ų055.8 Ų55.80%030%0.299CS..EExtended strand (participates in β ladder)trans-120.4156.9178.3-69.7158.2000109.7A20 L36 V69 A73 M83 V84 L110 V114 I120A20-L71 HydrophobicContact CB-CD2 3.59Å; A20-L71 HydrophobicContact CB-CG 4.46Å; L36-L71 HydrophobicContact CB-CD2 4.16Å; L36-L71 HydrophobicContact CD1-CD1 4.3Å; V69-L71 HydrophobicContact CG1-CD1 4.45Å; V69-L71 HydrophobicContact CG1-CG 4.15Å; L71-A73 VanDerWaalsContact C-N 3.3Å; L71-A73 PolarHBondContact O-N 2.92Å; L71-M83 CarbonylContact O-C 3.3Å; L71-M83 VanDerWaalsContact O-CA 3.29Å; L71-M83 WeakPolarHBondContact O-CA 3.39Å; L71-V84 PolarHBondContact N-O 3.43Å; L71-V84 PolarHBondContact O-N 3.17Å; L71-L110 HydrophobicContact CD1-CD1 4.13Å; L71-V114 HydrophobicContact CD1-CB 4.32Å; L71-V114 HydrophobicContact CD1-CG1 4.41Å; L71-V114 HydrophobicContact CD1-CG2 3.85Å; L71-I120 HydrophobicContact CB-CD1 3.84Å; L71-I120 HydrophobicContact CB-CG1 4.18Å; L71-I120 HydrophobicContact CB-CG2 4.26Å
72G92.1Very high82.5Confident9 Ų952.8 Ų52.89%0.09329%0.286CS..SBendtrans75.218.2175.700000114.5
73A89Confident83.3Confident16 Ų1654.1 Ų54.113%0.13229%0.292CS..  trans-90.6134.317600000111.1I70 L71 M76 M83 W143I70-A73 HydrophobicContact CG2-CB 4.32Å; L71-A73 VanDerWaalsContact C-N 3.3Å; L71-A73 PolarHBondContact O-N 2.92Å; A73-M76 HydrophobicContact CB-SD 3.61Å; A73-M83 HydrophobicContact CB-CE 3.55Å; A73-M83 HydrophobicContact CB-CG 4.07Å; A73-M83 HydrophobicContact CB-SD 4.36Å; A73-W143 WeakPolarHBondContact O-CZ2 3.49Å
74H87.4Confident83.8Confident45 Ų4553.6 Ų53.621%0.20829%0.285CS..SBendtrans-103.3-54.3166.5-178.265.7000111.3A11 R13 E80 W143A11-H74 PolarHBondContact O-CE1 2.88Å; R13-H74 HydrophobicContact CG-CB 4.27Å; R13-H74 VanDerWaalsContact CG-CD2 3.43Å; R13-H74 WeakPolarHBondContact CG-CD2 3.39Å; H74-E80 WeakPolarHBondContact CB-OE1 3.32Å; H74-E80 WeakPolarHBondContact CB-OE2 3.45Å; H74-E80 PolarHBondContact N-OE2 3.19Å; H74-W143 PolarHBondContact O-NE1 2.92Å
75E81.4Confident84.3Confident43 Ų4357.5 Ų57.520%0.20130%0.295CS..  trans-105.8113.6172.4-177.668.3-126.600110.4R4 R77 D78 E80 M83R4-E75 IonicContact CZ-OE1 3.53Å; R4-E75 VanDerWaalsContact CZ-OE1 3.24Å; R4-E75 IonicContact CZ-OE2 2.83Å; R4-E75 IonicContact NH1-OE1 3.44Å; R4-E75 PolarHBondContact NH1-OE1 2.8Å; R4-E75 IonicContact NH1-OE2 3.57Å; R4-E75 PolarHBondContact NH1-OE2 2.74Å; R4-E75 IonicContact NH2-OE1 2.79Å; R4-E75 PolarHBondContact NH2-OE1 2.97Å; E75-R77 HydrophobicContact CG-CB 4.26Å; E75-R77 PolarHBondContact O-N 2.99Å; E75-D78 HydrophobicContact CB-CB 4.45Å; E75-D78 HydrophobicContact CG-CB 4.31Å; E75-D78 PolarHBondContact O-N 3.28Å; E75-D78 VanDerWaalsContact O-O 3.08Å; E75-E80 PolarHBondContact N-OE1 2.78Å; E75-E80 VanDerWaalsContact N-OE1 3.11Å; E75-M83 WeakPolarHBondContact O-CE 3.14Å
76M78.6Confident84.9Confident53 Ų5356.4 Ų56.426%0.26128%0.277SS..THydrogen-bonded Turntrans-69-17.3-178.3-73.7-59.8-5700114.3Y21 I70 A73 W143Y21-M76 HydrophobicContact CD1-CE 3.31Å; Y21-M76 HydrophobicContact CD1-SD 4.37Å; Y21-M76 HydrophobicContact CD2-CE 3.77Å; Y21-M76 HydrophobicContact CD2-CG 4.16Å; Y21-M76 HydrophobicContact CD2-SD 4.04Å; Y21-M76 HydrophobicContact CE1-CE 3.55Å; Y21-M76 HydrophobicContact CE2-CE 4Å; Y21-M76 HydrophobicContact CE2-CG 4.41Å; Y21-M76 HydrophobicContact CG-CE 3.39Å; Y21-M76 HydrophobicContact CG-SD 3.86Å; I70-M76 HydrophobicContact CD1-CE 4.11Å; A73-M76 HydrophobicContact CB-SD 3.61Å; M76-W143 HydrophobicContact CG-CD2 4.18Å; M76-W143 HydrophobicContact CG-CG 3.9Å
77R73.5Confident85.2Confident207 Ų20757.7 Ų57.778%0.78128%0.283SS*.THydrogen-bonded Turntrans-79.4-18.7177.2-66.7-178.6177.8174.1-0.4113.3E75E75-R77 HydrophobicContact CG-CB 4.26Å; E75-R77 PolarHBondContact O-N 2.99Å
78D71.9Confident85.3Confident94 Ų9458 Ų5850%0.50329%0.285SS..SBendtrans-111.3139.8-177.1-68.2-25.7000110E75 E80 M83E75-D78 HydrophobicContact CB-CB 4.45Å; E75-D78 HydrophobicContact CG-CB 4.31Å; E75-D78 PolarHBondContact O-N 3.28Å; E75-D78 VanDerWaalsContact O-O 3.08Å; D78-E80 PolarHBondContact O-N 3.09Å; D78-M83 WeakPolarHBondContact O-CE 3.21Å
79I74.2Confident85.2Confident168 Ų16861.8 Ų61.886%0.86230%0.301SS*.  trans-78.7104.6171.5-60.1173.4000108.1
80E78.5Confident84.9Confident21 Ų2163.4 Ų63.410%0.09831%0.309CS..  trans-90.4142.3-179.9-63.6178.8162.200111.6R13 H74 E75 D78 A82 M83R13-E80 IonicContact CZ-OE1 3.55Å; R13-E80 IonicContact NH1-OE1 3.88Å; R13-E80 PolarHBondContact NH1-OE1 2.82Å; R13-E80 IonicContact NH1-OE2 4Å; R13-E80 IonicContact NH2-OE1 2.77Å; H74-E80 WeakPolarHBondContact CB-OE1 3.32Å; H74-E80 WeakPolarHBondContact CB-OE2 3.45Å; H74-E80 PolarHBondContact N-OE2 3.19Å; E75-E80 PolarHBondContact N-OE1 2.78Å; E75-E80 VanDerWaalsContact N-OE1 3.11Å; D78-E80 PolarHBondContact O-N 3.09Å; E80-A82 PolarHBondContact O-N 2.93Å; E80-A82 VanDerWaalsContact O-N 3.09Å; E80-M83 HydrophobicContact CB-CE 3.98Å; E80-M83 HydrophobicContact CB-CG 3.98Å; E80-M83 HydrophobicContact CB-SD 4.43Å; E80-M83 HydrophobicContact CG-CE 3.98Å; E80-M83 PolarHBondContact N-SD 2.79Å; E80-M83 VanDerWaalsContact O-CB 3.3Å; E80-M83 WeakPolarHBondContact O-CB 3.48Å; E80-M83 WeakPolarHBondContact O-CG 2.96Å; E80-M83 PolarHBondContact O-N 3.21Å
81P78.7Confident84.8Confident141 Ų14163.2 Ų63.292%0.91631%0.307SS*.THydrogen-bonded Turntrans-58.9-25.7-177.8-25.133.7000114.8M83P81-M83 VanDerWaalsContact C-N 3.31Å
82A85Confident84.4Confident24 Ų2463.8 Ų63.820%0.19831%0.311CS..THydrogen-bonded Turntrans-81.6-8.6178.600000113.4E80 V84 E119E80-A82 PolarHBondContact O-N 2.93Å; E80-A82 VanDerWaalsContact O-N 3.09Å; A82-V84 PolarHBondContact O-N 2.89Å; A82-E119 HydrophobicContact CB-CB 3.69Å; A82-E119 HydrophobicContact CB-CG 3.52Å
83M90.9Very high84Confident44 Ų4465.9 Ų65.922%0.21732%0.322CS..  trans-65126-179-70.5-175.2178.700111.5I70 L71 A73 E75 D78 E80 P81I70-M83 HydrophobicContact CG2-CB 4.41Å; I70-M83 HydrophobicContact CG2-CG 4.41Å; I70-M83 HydrophobicContact CG2-SD 4.44Å; L71-M83 CarbonylContact O-C 3.3Å; L71-M83 VanDerWaalsContact O-CA 3.29Å; L71-M83 WeakPolarHBondContact O-CA 3.39Å; A73-M83 HydrophobicContact CB-CE 3.55Å; A73-M83 HydrophobicContact CB-CG 4.07Å; A73-M83 HydrophobicContact CB-SD 4.36Å; E75-M83 WeakPolarHBondContact O-CE 3.14Å; D78-M83 WeakPolarHBondContact O-CE 3.21Å; E80-M83 HydrophobicContact CB-CE 3.98Å; E80-M83 HydrophobicContact CB-CG 3.98Å; E80-M83 HydrophobicContact CB-SD 4.43Å; E80-M83 HydrophobicContact CG-CE 3.98Å; E80-M83 PolarHBondContact N-SD 2.79Å; E80-M83 VanDerWaalsContact O-CB 3.3Å; E80-M83 WeakPolarHBondContact O-CB 3.48Å; E80-M83 WeakPolarHBondContact O-CG 2.96Å; E80-M83 PolarHBondContact O-N 3.21Å; P81-M83 VanDerWaalsContact C-N 3.31Å
84V88.4Confident83.4Confident34 Ų3466.9 Ų66.921%0.20632%0.324CS..EExtended strand (participates in β ladder)trans-117.6113.6175.4178.20000109.5L71 A82 R86 V114 I120L71-V84 PolarHBondContact N-O 3.43Å; L71-V84 PolarHBondContact O-N 3.17Å; A82-V84 PolarHBondContact O-N 2.89Å; V84-R86 HydrophobicContact CG1-CG 4.34Å; V84-R86 VanDerWaalsContact CG1-CZ 3.45Å; V84-R86 VanDerWaalsContact CG1-NH1 3.26Å; V84-V114 HydrophobicContact CB-CG1 4.34Å; V84-V114 HydrophobicContact CG1-CG1 3.96Å; V84-V114 HydrophobicContact CG1-CG2 3.97Å; V84-V114 HydrophobicContact CG2-CG1 4.47Å; V84-I120 HydrophobicContact CB-CD1 3.63Å; V84-I120 HydrophobicContact CG2-CD1 3.37Å
85Y90Very high82.6Confident117 Ų11771.9 Ų71.946%0.45935%0.346SS..EExtended strand (participates in β ladder)trans-89.4135.7174.6173.5-88.7000111.8H68 V69 I70 R87H68-Y85 HydrophobicContact CB-CE2 3.7Å; H68-Y85 PolarHBondContact CE1-OH 3.41Å; H68-Y85 AromaticContact CG-CE2 3.95Å; H68-Y85 AromaticContact CG-CZ 3.97Å; H68-Y85 AromaticContact ND1-CE2 3.72Å; H68-Y85 AromaticContact ND1-CZ 3.26Å; H68-Y85 VanDerWaalsContact ND1-CZ 3.26Å; H68-Y85 PolarHBondContact ND1-OH 2.73Å; V69-Y85 CarbonylContact O-C 3.58Å; V69-Y85 WeakPolarHBondContact O-CA 3.43Å; I70-Y85 HydrophobicContact CG1-CD2 4.1Å; Y85-R87 HydrophobicContact CE1-CG 4.08Å
86R90.4Very high81.7Confident66 Ų6671.3 Ų71.325%0.24934%0.342CS..EExtended strand (participates in β ladder)trans-139.3142.2175.4-67.9-65.2-178.6-94.51.3110.9V69 V84 L110 S112 V114V69-R86 PolarHBondContact N-O 2.93Å; V69-R86 PolarHBondContact O-N 3.11Å; V84-R86 HydrophobicContact CG1-CG 4.34Å; V84-R86 VanDerWaalsContact CG1-CZ 3.45Å; V84-R86 VanDerWaalsContact CG1-NH1 3.26Å; R86-L110 HydrophobicContact CB-CB 4.19Å; R86-L110 HydrophobicContact CB-CD1 4.14Å; R86-L110 HydrophobicContact CB-CD2 4.1Å; R86-L110 HydrophobicContact CB-CG 4.37Å; R86-L110 HydrophobicContact CG-CD1 4.12Å; R86-S112 WeakPolarHBondContact CD-O 3.23Å; R86-S112 WeakPolarHBondContact CD-OG 3.33Å; R86-S112 PolarHBondContact NE-O 2.84Å; R86-S112 PolarHBondContact NE-OG 2.83Å; R86-S112 VanDerWaalsContact NE-OG 3.14Å; R86-V114 HydrophobicContact CG-CG2 3.7Å
87R84.9Confident81Confident79 Ų7971.7 Ų71.730%0.29835%0.345SS..EExtended strand (participates in β ladder)trans-84.8155.9169.3-64.9-172.1-70.6170.49.4109.7Y85 L110 S111 E861Y85-R87 HydrophobicContact CE1-CG 4.08Å; R87-L110 CarbonylContact O-C 3.52Å; R87-S111 WeakPolarHBondContact O-CB 3.34Å; R87-S111 PolarHBondContact O-N 3.23Å; R87-S111 PolarHBondContact O-OG 3.07Å; R87-E861 IonicContact CZ-OE1 3.9Å; R87-E861 IonicContact NH1-OE1 3.4Å; R87-E861 PolarHBondContact NH1-OE1 2.84Å; R87-E861 IonicContact NH2-OE1 3.99Å; R87-E861 PolarHBondContact NH2-OE1 3.23Å
88V88.6Confident80.5Confident7 Ų765.1 Ų65.14%0.04232%0.321CS..EExtended strand (participates in β ladder)trans-83.5126.31711790000109.9P64 L67 V69 N90 L108 K109P64-V88 CarbonylContact C-O 3.57Å; P64-V88 HydrophobicContact CB-CG1 4.27Å; L67-V88 HydrophobicContact CB-CB 3.82Å; L67-V88 HydrophobicContact CB-CG2 3.48Å; L67-V88 VanDerWaalsContact CB-CG2 3.48Å; L67-V88 HydrophobicContact CD1-CB 4.48Å; L67-V88 HydrophobicContact CD1-CG1 4.38Å; L67-V88 HydrophobicContact CD1-CG2 4.39Å; L67-V88 PolarHBondContact O-N 2.98Å; V69-V88 HydrophobicContact CG2-CG2 3.99Å; V88-N90 WeakPolarHBondContact CG1-O 3.42Å; V88-L108 HydrophobicContact CG1-CB 4.4Å; V88-L108 HydrophobicContact CG1-CD2 4.02Å; V88-L108 HydrophobicContact CG2-CB 4.3Å; V88-L108 HydrophobicContact CG2-CD1 4.06Å; V88-L108 HydrophobicContact CG2-CD2 4.26Å; V88-L108 HydrophobicContact CG2-CG 4.46Å; V88-K109 CarbonylContact C-O 3.59Å
89K84.2Confident80Confident100 Ų10066.8 Ų66.844%0.43533%0.329SS..EExtended strand (participates in β ladder)trans-79.4-44176.6-174.8179.4172.4-173.50111.6K109 E209K89-K109 HydrophobicContact CB-CG 4.28Å; K89-K109 WeakPolarHBondContact CB-O 3.49Å; K89-K109 HydrophobicContact CD-CG 4.31Å; K89-K109 PolarHBondContact N-O 2.89Å; K89-E209 IonicContact NZ-OE1 3.21Å; K89-E209 PolarHBondContact NZ-OE1 2.95Å
90N87.8Confident79.6Confident33 Ų3363.1 Ų63.118%0.17631%0.312CS..EExtended strand (participates in β ladder)trans-160.9166178.9-159.312.7000108.7V88 K109 I208 V211V88-N90 WeakPolarHBondContact CG1-O 3.42Å; N90-K109 WeakPolarHBondContact O-CB 3.39Å; N90-K109 PolarHBondContact O-N 2.88Å; N90-I208 PolarHBondContact ND2-O 2.77Å; N90-V211 PolarHBondContact ND2-O 2.9Å
91Y90.3Very high79Confident27 Ų2764.7 Ų64.711%0.10632%0.321CS..EExtended strand (participates in β ladder)trans-140.3161.1169.360.4-96.1000111.1I55 N61 L62 P64 L67 T93 T106 L107 L108I55-Y91 HydrophobicContact CG2-CD1 4.11Å; I55-Y91 HydrophobicContact CG2-CD2 3.99Å; I55-Y91 HydrophobicContact CG2-CE1 3.87Å; I55-Y91 HydrophobicContact CG2-CE2 3.76Å; I55-Y91 HydrophobicContact CG2-CG 4.17Å; N61-Y91 WeakPolarHBondContact CB-OH 3.48Å; L62-Y91 WeakPolarHBondContact O-CE1 3.47Å; L62-Y91 VanDerWaalsContact O-CZ 3.22Å; L62-Y91 PolarHBondContact O-OH 3.4Å; P64-Y91 HydrophobicContact CB-CD1 4.45Å; P64-Y91 HydrophobicContact CG-CD1 3.98Å; P64-Y91 HydrophobicContact CG-CE1 3.83Å; L67-Y91 HydrophobicContact CD1-CD1 3.96Å; L67-Y91 HydrophobicContact CD1-CE1 4.25Å; Y91-T93 HydrophobicContact CD2-CG2 3.76Å; Y91-T93 HydrophobicContact CE2-CG2 3.84Å; Y91-T106 HydrophobicContact CD2-CG2 4.21Å; Y91-T106 HydrophobicContact CG-CG2 4.46Å; Y91-L107 CarbonylContact C-O 3.59Å; Y91-L107 WeakPolarHBondContact CA-O 3.3Å; Y91-L107 VanDerWaalsContact CB-O 3.25Å; Y91-L107 WeakPolarHBondContact CB-O 3.29Å; Y91-L108 HydrophobicContact CG-CD2 4.35Å
92A85.6Confident78.7Confident12 Ų1261.6 Ų61.610%0.09930%0.297CS..EExtended strand (participates in β ladder)trans-132.4115.4174.600000108.9L107 T204 I208A92-L107 PolarHBondContact N-O 3.16Å; A92-L107 PolarHBondContact O-N 3.02Å; A92-T204 HydrophobicContact CB-CG2 3.41Å; A92-T204 VanDerWaalsContact CB-CG2 3.41Å; A92-I208 HydrophobicContact CB-CD1 3.99Å; A92-I208 HydrophobicContact CB-CG1 4.09Å
93T84.3Confident78.6Confident52 Ų5261.9 Ų61.932%0.31930%0.295SS..EExtended strand (participates in β ladder)trans-89.2142.9175.470.40000109T52 Y91 T106T52-T93 HydrophobicContact CG2-CG2 4.07Å; Y91-T93 HydrophobicContact CD2-CG2 3.76Å; Y91-T93 HydrophobicContact CE2-CG2 3.84Å; T93-T106 WeakPolarHBondContact CA-OG1 3.49Å; T93-T106 WeakPolarHBondContact CB-OG1 3.27Å; T93-T106 HydrophobicContact CG2-CG2 3.94Å; T93-T106 VanDerWaalsContact CG2-OG1 3.3Å; T93-T106 WeakPolarHBondContact CG2-OG1 3.3Å
94H76.7Confident78.4Confident38 Ų3859.8 Ų59.818%0.17629%0.285CS..  trans-68.2167.9163-160.7-85000109.5Y96 N103 I105 Y197 W200H94-Y96 PolarHBondContact O-N 3.13Å; H94-N103 HydrophobicContact CB-CB 4.11Å; H94-N103 PolarHBondContact CE1-OD1 2.86Å; H94-N103 VanDerWaalsContact CE1-OD1 3.27Å; H94-N103 VanDerWaalsContact ND1-CB 3.26Å; H94-N103 WeakPolarHBondContact ND1-CB 3.4Å; H94-N103 VanDerWaalsContact ND1-CG 3.31Å; H94-N103 PolarHBondContact ND1-OD1 2.67Å; H94-I105 HydrophobicContact CB-CG2 3.83Å; H94-I105 PolarHBondContact N-O 3.26Å; H94-I105 VanDerWaalsContact N-O 3.07Å; H94-Y197 AromaticContact CD2-CD1 3.94Å; H94-Y197 AromaticContact CD2-CE1 3.92Å; H94-W200 HydrophobicContact CB-CH2 3.99Å; H94-W200 HydrophobicContact CB-CZ2 3.8Å; H94-W200 AromaticContact CD2-CD1 3.66Å; H94-W200 AromaticContact CD2-CD2 3.61Å; H94-W200 AromaticContact CD2-CE2 3.51Å; H94-W200 AromaticContact CD2-CG 3.73Å; H94-W200 AromaticContact CD2-NE1 3.53Å
95F70.7Confident78.6Confident150 Ų15058.2 Ų58.266%0.65828%0.275SS*.  trans-65.778.7174.1-65-79.8000110.7N97 N103F95-N97 PolarHBondContact O-N 2.77Å; F95-N103 WeakPolarHBondContact O-CB 3.18Å; F95-N103 PolarHBondContact O-ND2 2.74Å
96Y63.4Low78.7Confident30 Ų3052.6 Ų52.612%0.11825%0.253CS..  trans-68.6128.3-178.2177.3-121.6000110.6T52 H53 H94 Y98 D101 D102 D104T52-Y96 HydrophobicContact CG2-CD1 3.89Å; T52-Y96 HydrophobicContact CG2-CG 3.8Å; H53-Y96 HydrophobicContact CB-CE1 4.46Å; H94-Y96 PolarHBondContact O-N 3.13Å; Y96-Y98 AromaticContact CD1-CD1 3.69Å; Y96-Y98 HydrophobicContact CD1-CD1 3.69Å; Y96-Y98 HydrophobicContact CD1-CD2 4.16Å; Y96-Y98 AromaticContact CD1-CE1 3.44Å; Y96-Y98 HydrophobicContact CD1-CE1 3.44Å; Y96-Y98 VanDerWaalsContact CD1-CE1 3.44Å; Y96-Y98 AromaticContact CD1-CE2 3.93Å; Y96-Y98 HydrophobicContact CD1-CE2 3.93Å; Y96-Y98 HydrophobicContact CD1-CG 4.03Å; Y96-Y98 AromaticContact CD1-CZ 3.54Å; Y96-Y98 AromaticContact CE1-CD1 3.3Å; Y96-Y98 HydrophobicContact CE1-CD1 3.3Å; Y96-Y98 AromaticContact CE1-CE1 3.28Å; Y96-Y98 HydrophobicContact CE1-CE1 3.28Å; Y96-Y98 AromaticContact CE1-CG 3.96Å; Y96-Y98 HydrophobicContact CE1-CG 3.96Å; Y96-Y98 AromaticContact CE1-CZ 3.92Å; Y96-D101 HydrophobicContact CE2-CB 4.18Å; Y96-D101 PolarHBondContact OH-OD1 2.84Å; Y96-D102 WeakPolarHBondContact CA-O 3.49Å; Y96-D102 VanDerWaalsContact CD2-O 3.28Å; Y96-D102 WeakPolarHBondContact CD2-O 3.48Å; Y96-D104 HydrophobicContact CD2-CB 3.91Å; Y96-D104 HydrophobicContact CE2-CB 3.6Å
97N64.1Low78.9Confident62 Ų6249.5 Ų49.533%0.33224%0.241SC..BIsolated β-bridgetrans-99.5101.7178.7-177.90.7000109.7F95 D99 N100 D101 D102F95-N97 PolarHBondContact O-N 2.77Å; N97-D99 PolarHBondContact O-N 2.86Å; N97-D99 VanDerWaalsContact O-N 3.1Å; N97-D99 PolarHBondContact OD1-N 2.99Å; N97-D99 VanDerWaalsContact OD1-N 3.08Å; N97-N100 WeakPolarHBondContact CB-OD1 3.33Å; N97-N100 PolarHBondContact ND2-OD1 2.93Å; N97-N100 PolarHBondContact O-N 3.25Å; N97-N100 PolarHBondContact O-OD1 3.15Å; N97-D101 WeakPolarHBondContact O-CA 3.44Å; N97-D101 PolarHBondContact O-N 3.46Å; N97-D102 HydrophobicContact CB-CB 4.2Å; N97-D102 PolarHBondContact N-O 2.93Å; N97-D102 PolarHBondContact O-N 3.26Å
98Y62.6Low79.4Confident69 Ų6945.7 Ų45.727%0.27123%0.227SC..THydrogen-bonded Turntrans-64.4-11.6-179.2-65.7-84.2000114.9A56 S57 R58 Y96A56-Y98 VanDerWaalsContact C-OH 3.26Å; A56-Y98 WeakPolarHBondContact CB-OH 3.46Å; A56-Y98 PolarHBondContact O-OH 3.44Å; S57-Y98 VanDerWaalsContact C-OH 3.24Å; S57-Y98 PolarHBondContact N-OH 2.88Å; S57-Y98 PolarHBondContact O-OH 3.21Å; R58-Y98 HydrophobicContact CB-CD1 4.43Å; R58-Y98 HydrophobicContact CB-CG 4.48Å; R58-Y98 HydrophobicContact CG-CD1 3.54Å; R58-Y98 HydrophobicContact CG-CD2 3.92Å; R58-Y98 HydrophobicContact CG-CE1 4.2Å; R58-Y98 HydrophobicContact CG-CG 3.39Å; R58-Y98 VanDerWaalsContact N-CE1 3.28Å; R58-Y98 VanDerWaalsContact NH2-C 3.29Å; R58-Y98 PolarHBondContact NH2-O 2.75Å; Y96-Y98 AromaticContact CD1-CD1 3.69Å; Y96-Y98 HydrophobicContact CD1-CD1 3.69Å; Y96-Y98 HydrophobicContact CD1-CD2 4.16Å; Y96-Y98 AromaticContact CD1-CE1 3.44Å; Y96-Y98 HydrophobicContact CD1-CE1 3.44Å; Y96-Y98 VanDerWaalsContact CD1-CE1 3.44Å; Y96-Y98 AromaticContact CD1-CE2 3.93Å; Y96-Y98 HydrophobicContact CD1-CE2 3.93Å; Y96-Y98 HydrophobicContact CD1-CG 4.03Å; Y96-Y98 AromaticContact CD1-CZ 3.54Å; Y96-Y98 AromaticContact CE1-CD1 3.3Å; Y96-Y98 HydrophobicContact CE1-CD1 3.3Å; Y96-Y98 AromaticContact CE1-CE1 3.28Å; Y96-Y98 HydrophobicContact CE1-CE1 3.28Å; Y96-Y98 AromaticContact CE1-CG 3.96Å; Y96-Y98 HydrophobicContact CE1-CG 3.96Å; Y96-Y98 AromaticContact CE1-CZ 3.92Å
99D60.6Low79.6Confident128 Ų12846.1 Ų46.168%0.68423%0.228SC*.THydrogen-bonded Turntrans-82.7-21.1178.3-69.7-34.9000112.8R58 N97R58-D99 IonicContact CZ-OD1 2.72Å; R58-D99 IonicContact NH1-OD1 2.77Å; R58-D99 PolarHBondContact NH1-OD1 2.95Å; R58-D99 IonicContact NH2-OD1 2.69Å; R58-D99 PolarHBondContact NH2-OD1 2.98Å; N97-D99 PolarHBondContact O-N 2.86Å; N97-D99 VanDerWaalsContact O-N 3.1Å; N97-D99 PolarHBondContact OD1-N 2.99Å; N97-D99 VanDerWaalsContact OD1-N 3.08Å
100N67.1Low80Confident92 Ų9241.4 Ų41.449%0.49221%0.207SC..THydrogen-bonded Turntrans-143.111.2-176.269.2-11.7000114.3N97 D102N97-N100 WeakPolarHBondContact CB-OD1 3.33Å; N97-N100 PolarHBondContact ND2-OD1 2.93Å; N97-N100 PolarHBondContact O-N 3.25Å; N97-N100 PolarHBondContact O-OD1 3.15Å; N100-D102 PolarHBondContact O-N 2.91Å; N100-D102 VanDerWaalsContact O-N 3.12Å; N100-D102 WeakPolarHBondContact OD1-CB 3.17Å; N100-D102 PolarHBondContact OD1-N 2.85Å; N100-D102 VanDerWaalsContact OD1-N 3.12Å
101D64.1Low80Confident53 Ų5342.5 Ų42.528%0.28322%0.218SC..THydrogen-bonded Turntrans54.824.9-176.2-59.6-49000114.7Y96 N97 L176Y96-D101 HydrophobicContact CE2-CB 4.18Å; Y96-D101 PolarHBondContact OH-OD1 2.84Å; N97-D101 WeakPolarHBondContact O-CA 3.44Å; N97-D101 PolarHBondContact O-N 3.46Å; D101-L176 HydrophobicContact CB-CD1 3.67Å; D101-L176 HydrophobicContact CB-CG 4.41Å; D101-L176 WeakPolarHBondContact OD2-CD1 3.5Å
102D73.2Confident79.9Confident77 Ų7742.5 Ų42.541%0.41222%0.222SC..BIsolated β-bridgetrans-75.5144.8178-170.726.3000111.1Y96 N97 N100Y96-D102 WeakPolarHBondContact CA-O 3.49Å; Y96-D102 VanDerWaalsContact CD2-O 3.28Å; Y96-D102 WeakPolarHBondContact CD2-O 3.48Å; N97-D102 HydrophobicContact CB-CB 4.2Å; N97-D102 PolarHBondContact N-O 2.93Å; N97-D102 PolarHBondContact O-N 3.26Å; N100-D102 PolarHBondContact O-N 2.91Å; N100-D102 VanDerWaalsContact O-N 3.12Å; N100-D102 WeakPolarHBondContact OD1-CB 3.17Å; N100-D102 PolarHBondContact OD1-N 2.85Å; N100-D102 VanDerWaalsContact OD1-N 3.12Å
103N82.2Confident80.1Confident30 Ų3044 Ų4416%0.1623%0.231CC..THydrogen-bonded Turntrans60.538-174.5-46-79.2000115.6H94 F95 I105 Y197H94-N103 HydrophobicContact CB-CB 4.11Å; H94-N103 PolarHBondContact CE1-OD1 2.86Å; H94-N103 VanDerWaalsContact CE1-OD1 3.27Å; H94-N103 VanDerWaalsContact ND1-CB 3.26Å; H94-N103 WeakPolarHBondContact ND1-CB 3.4Å; H94-N103 VanDerWaalsContact ND1-CG 3.31Å; H94-N103 PolarHBondContact ND1-OD1 2.67Å; F95-N103 WeakPolarHBondContact O-CB 3.18Å; F95-N103 PolarHBondContact O-ND2 2.74Å; N103-I105 PolarHBondContact O-N 3.05Å; N103-Y197 WeakPolarHBondContact CA-OH 3.37Å; N103-Y197 HydrophobicContact CB-CE1 4.39Å; N103-Y197 PolarHBondContact OD1-OH 3.29Å
104D87.8Confident80.5Confident0 Ų041.7 Ų41.70%022%0.216CC..  trans-7360.6177.3-16616.6000113.6T52 H53 Y96 S175 V192T52-D104 WeakPolarHBondContact CA-OD1 3.28Å; T52-D104 WeakPolarHBondContact CB-OD1 3.36Å; T52-D104 PolarHBondContact N-OD1 3.1Å; H53-D104 IonicContact CE1-OD2 3.17Å; H53-D104 IonicContact CG-OD1 2.9Å; H53-D104 IonicContact CG-OD2 2.97Å; H53-D104 PolarHBondContact N-OD1 2.92Å; H53-D104 IonicContact ND1-OD1 2.78Å; H53-D104 PolarHBondContact ND1-OD1 2.95Å; H53-D104 IonicContact ND1-OD2 3.5Å; H53-D104 PolarHBondContact ND1-OD2 2.98Å; Y96-D104 HydrophobicContact CD2-CB 3.91Å; Y96-D104 HydrophobicContact CE2-CB 3.6Å; D104-S175 WeakPolarHBondContact CB-OG 3.22Å; D104-S175 WeakPolarHBondContact OD2-CA 3.01Å; D104-S175 VanDerWaalsContact OD2-CB 3.26Å; D104-S175 WeakPolarHBondContact OD2-CB 3.42Å; D104-S175 PolarHBondContact OD2-OG 3.46Å; D104-V192 HydrophobicContact CB-CG2 3.94Å; D104-V192 WeakPolarHBondContact O-CG2 3.28Å
105I92.1Very high81.2Confident0 Ų044.3 Ų44.30%023%0.232CC..  trans-138.8132.5-179.4-172.3173.3000112.4I49 T52 H94 N103 V173 V192 M194 Y197 W200 I201I49-I105 HydrophobicContact CG2-CD1 4.02Å; I49-I105 HydrophobicContact CG2-CG1 3.9Å; T52-I105 PolarHBondContact OG1-N 2.98Å; T52-I105 PolarHBondContact OG1-O 3.34Å; H94-I105 HydrophobicContact CB-CG2 3.83Å; H94-I105 PolarHBondContact N-O 3.26Å; H94-I105 VanDerWaalsContact N-O 3.07Å; N103-I105 PolarHBondContact O-N 3.05Å; I105-V173 HydrophobicContact CD1-CG2 4.33Å; I105-V173 HydrophobicContact CG1-CG2 4.47Å; I105-V192 HydrophobicContact CB-CG1 4.43Å; I105-M194 HydrophobicContact CD1-CE 4.5Å; I105-M194 HydrophobicContact CD1-SD 3.59Å; I105-M194 VanDerWaalsContact CD1-SD 3.59Å; I105-Y197 HydrophobicContact CD1-CG 4.32Å; I105-Y197 HydrophobicContact CG2-CD1 3.79Å; I105-Y197 HydrophobicContact CG2-CE1 3.79Å; I105-Y197 HydrophobicContact CG2-CG 4.22Å; I105-W200 HydrophobicContact CD1-CZ3 4.12Å; I105-W200 HydrophobicContact CG1-CZ3 4.11Å; I105-W200 HydrophobicContact CG2-CH2 4.27Å; I105-W200 HydrophobicContact CG2-CZ3 3.87Å; I105-I201 HydrophobicContact CD1-CD1 4.24Å; I105-I201 HydrophobicContact CD1-CG1 4.5Å
106T93.1Very high82.3Confident0 Ų040 Ų400%021%0.212CC..EExtended strand (participates in β ladder)trans-135.4137.5178.5-69.80000111.9T50 T52 I55 Y91 T93 L108T50-T106 PolarHBondContact N-O 2.79Å; T50-T106 PolarHBondContact O-N 3.31Å; T52-T106 VanDerWaalsContact CA-OG1 3.28Å; T52-T106 WeakPolarHBondContact CA-OG1 3.04Å; T52-T106 WeakPolarHBondContact CB-OG1 3.19Å; T52-T106 PolarHBondContact OG1-OG1 2.86Å; I55-T106 HydrophobicContact CD1-CG2 3.44Å; I55-T106 VanDerWaalsContact CD1-CG2 3.44Å; Y91-T106 HydrophobicContact CD2-CG2 4.21Å; Y91-T106 HydrophobicContact CG-CG2 4.46Å; T93-T106 WeakPolarHBondContact CA-OG1 3.49Å; T93-T106 WeakPolarHBondContact CB-OG1 3.27Å; T93-T106 HydrophobicContact CG2-CG2 3.94Å; T93-T106 VanDerWaalsContact CG2-OG1 3.3Å; T93-T106 WeakPolarHBondContact CG2-OG1 3.3Å; T106-L108 HydrophobicContact CG2-CD2 4.3Å
107L94.3Very high83.7Confident0 Ų041.8 Ų41.80%023%0.225CC..EExtended strand (participates in β ladder)trans-97.1127.2171.6-87.961.2000109.9I47 I49 Y91 A92 W200 I201 T204 M205 I208I47-L107 HydrophobicContact CG2-CD2 4.32Å; I47-L107 HydrophobicContact CG2-CG 4.24Å; I49-L107 HydrophobicContact CD1-CD1 4.22Å; I49-L107 HydrophobicContact CG1-CD1 3.99Å; I49-L107 HydrophobicContact CG1-CG 4.12Å; Y91-L107 CarbonylContact C-O 3.59Å; Y91-L107 WeakPolarHBondContact CA-O 3.3Å; Y91-L107 VanDerWaalsContact CB-O 3.25Å; Y91-L107 WeakPolarHBondContact CB-O 3.29Å; A92-L107 PolarHBondContact N-O 3.16Å; A92-L107 PolarHBondContact O-N 3.02Å; L107-W200 HydrophobicContact CD1-CE3 4.38Å; L107-W200 HydrophobicContact CD1-CH2 3.68Å; L107-W200 HydrophobicContact CD1-CZ3 3.41Å; L107-W200 VanDerWaalsContact CD1-CZ3 3.41Å; L107-I201 HydrophobicContact CD1-CG1 4.33Å; L107-I201 HydrophobicContact CD2-CG2 4.34Å; L107-T204 HydrophobicContact CB-CG2 4.47Å; L107-T204 HydrophobicContact CD2-CG2 3.82Å; L107-M205 HydrophobicContact CD2-CG 3.68Å; L107-I208 HydrophobicContact CB-CD1 3.87Å; L107-I208 WeakPolarHBondContact O-CD1 3.06Å
108L94.4Very high84.9Confident0 Ų046.1 Ų46.10%024%0.244CC..EExtended strand (participates in β ladder)trans-99.3127.1171.6-60.8-176.7000110.1I22 I47 V48 T50 I55 L67 V69 V88 Y91 T106I22-L108 HydrophobicContact CD1-CD1 3.75Å; I22-L108 HydrophobicContact CG1-CD1 4.25Å; I22-L108 HydrophobicContact CG2-CD1 4.4Å; I47-L108 WeakPolarHBondContact CA-O 3.38Å; V48-L108 HydrophobicContact CB-CB 4.27Å; V48-L108 PolarHBondContact N-O 2.78Å; V48-L108 PolarHBondContact O-N 2.83Å; T50-L108 HydrophobicContact CG2-CD1 4.08Å; T50-L108 HydrophobicContact CG2-CG 4.16Å; I55-L108 HydrophobicContact CD1-CD1 4.49Å; I55-L108 HydrophobicContact CD1-CD2 3.48Å; I55-L108 VanDerWaalsContact CD1-CD2 3.48Å; I55-L108 HydrophobicContact CD1-CG 4.22Å; L67-L108 HydrophobicContact CD1-CD2 4.04Å; V69-L108 HydrophobicContact CG2-CD1 4.15Å; V88-L108 HydrophobicContact CG1-CB 4.4Å; V88-L108 HydrophobicContact CG1-CD2 4.02Å; V88-L108 HydrophobicContact CG2-CB 4.3Å; V88-L108 HydrophobicContact CG2-CD1 4.06Å; V88-L108 HydrophobicContact CG2-CD2 4.26Å; V88-L108 HydrophobicContact CG2-CG 4.46Å; Y91-L108 HydrophobicContact CG-CD2 4.35Å; T106-L108 HydrophobicContact CG2-CD2 4.3Å
109K92.6Very high86.3Confident15 Ų1545.4 Ų45.47%0.06524%0.243CC..EExtended strand (participates in β ladder)trans-93.4118.4169-175.867.4167.6-171.80109D46 I47 V88 K89 N90 I208D46-K109 HydrophobicContact CB-CD 4.47Å; D46-K109 VanDerWaalsContact CG-CE 3.44Å; D46-K109 IonicContact OD1-NZ 3.3Å; D46-K109 PolarHBondContact OD1-NZ 2.91Å; D46-K109 WeakPolarHBondContact OD2-CE 3.49Å; D46-K109 IonicContact OD2-NZ 3.85Å; D46-K109 PolarHBondContact OD2-NZ 3.16Å; I47-K109 HydrophobicContact CD1-CD 3.49Å; I47-K109 VanDerWaalsContact CD1-CD 3.49Å; V88-K109 CarbonylContact C-O 3.59Å; K89-K109 HydrophobicContact CB-CG 4.28Å; K89-K109 WeakPolarHBondContact CB-O 3.49Å; K89-K109 HydrophobicContact CD-CG 4.31Å; K89-K109 PolarHBondContact N-O 2.89Å; N90-K109 WeakPolarHBondContact O-CB 3.39Å; N90-K109 PolarHBondContact O-N 2.88Å; K109-I208 HydrophobicContact CB-CD1 4.01Å; K109-I208 HydrophobicContact CB-CG1 4.15Å; K109-I208 HydrophobicContact CB-CG2 4.25Å; K109-I208 HydrophobicContact CD-CG2 3.97Å; K109-I208 HydrophobicContact CG-CG2 4.31Å
110L92.8Very high87.9Confident1 Ų139.4 Ų39.41%0.00521%0.211CC..EExtended strand (participates in β ladder)trans-71.7152.1176.4-55-176.9000111.2D46 V48 V69 L71 R86 R87 S112 V114D46-L110 HydrophobicContact CB-CB 4.1Å; D46-L110 WeakPolarHBondContact O-CG 3.42Å; D46-L110 PolarHBondContact O-N 2.89Å; V48-L110 HydrophobicContact CG2-CD1 4.2Å; V48-L110 HydrophobicContact CG2-CD2 4.24Å; V48-L110 HydrophobicContact CG2-CG 4.4Å; V69-L110 HydrophobicContact CB-CD2 3.8Å; V69-L110 HydrophobicContact CG1-CD2 4.14Å; V69-L110 HydrophobicContact CG2-CD2 3.66Å; L71-L110 HydrophobicContact CD1-CD1 4.13Å; R86-L110 HydrophobicContact CB-CB 4.19Å; R86-L110 HydrophobicContact CB-CD1 4.14Å; R86-L110 HydrophobicContact CB-CD2 4.1Å; R86-L110 HydrophobicContact CB-CG 4.37Å; R86-L110 HydrophobicContact CG-CD1 4.12Å; R87-L110 CarbonylContact O-C 3.52Å; L110-S112 PolarHBondContact O-N 2.97Å; L110-S112 VanDerWaalsContact O-N 3.16Å; L110-V114 HydrophobicContact CD1-CG2 4.1Å
111S87.4Confident89.2Confident57 Ų5736.7 Ų36.740%0.39920%0.199SC..EExtended strand (participates in β ladder)trans-59.4-25.3178.162.50000113.7R87R87-S111 WeakPolarHBondContact O-CB 3.34Å; R87-S111 PolarHBondContact O-N 3.23Å; R87-S111 PolarHBondContact O-OG 3.07Å
112S88Confident90.8Very high26 Ų2635.5 Ų35.518%0.18219%0.194CC..EExtended strand (participates in β ladder)trans-159.1147.3175.754.40000109.6R86 L110R86-S112 WeakPolarHBondContact CD-O 3.23Å; R86-S112 WeakPolarHBondContact CD-OG 3.33Å; R86-S112 PolarHBondContact NE-O 2.84Å; R86-S112 PolarHBondContact NE-OG 2.83Å; R86-S112 VanDerWaalsContact NE-OG 3.14Å; L110-S112 PolarHBondContact O-N 2.97Å; L110-S112 VanDerWaalsContact O-N 3.16Å
113P90Very high91.8Very high44 Ų4432 Ų3229%0.28618%0.175SC..EExtended strand (participates in β ladder)trans-55.2154.4174.5-23.332.5000114.3Q44 S45 D46Q44-P113 HydrophobicContact CB-CB 4.04Å; Q44-P113 HydrophobicContact CG-CB 4.03Å; S45-P113 CarbonylContact O-C 3.59Å; S45-P113 WeakPolarHBondContact O-CA 3.3Å; D46-P113 HydrophobicContact CB-CB 4.24Å; D46-P113 HydrophobicContact CB-CG 4.09Å
114V92.4Very high92.3Very high3 Ų332.7 Ų32.72%0.01818%0.182CC..EExtended strand (participates in β ladder)trans-112.9129.1173-175.90000107.8Q44 S45 L71 V84 R86 L110 I120Q44-V114 CarbonylContact C-O 3.51Å; Q44-V114 WeakPolarHBondContact CA-O 3.35Å; Q44-V114 WeakPolarHBondContact CB-O 3.36Å; S45-V114 PolarHBondContact N-O 2.77Å; S45-V114 PolarHBondContact O-N 3.33Å; L71-V114 HydrophobicContact CD1-CB 4.32Å; L71-V114 HydrophobicContact CD1-CG1 4.41Å; L71-V114 HydrophobicContact CD1-CG2 3.85Å; V84-V114 HydrophobicContact CB-CG1 4.34Å; V84-V114 HydrophobicContact CG1-CG1 3.96Å; V84-V114 HydrophobicContact CG1-CG2 3.97Å; V84-V114 HydrophobicContact CG2-CG1 4.47Å; R86-V114 HydrophobicContact CG-CG2 3.7Å; L110-V114 HydrophobicContact CD1-CG2 4.1Å; V114-I120 HydrophobicContact CG1-CB 4.5Å; V114-I120 HydrophobicContact CG1-CD1 3.96Å; V114-I120 HydrophobicContact CG1-CG2 3.77Å
115N93.1Very high92.5Very high94 Ų9434 Ų3450%0.50319%0.189SC..EExtended strand (participates in β ladder)trans-72.7146.2178.5-66-20.5000110.2T117N115-T117 PolarHBondContact O-N 2.81Å
116Y93.4Very high92.3Very high60 Ų6034 Ų3424%0.23519%0.189CC..  trans-72.9128.2175.2-55.2-19.2000110.5L36 D38 G42 N43 Q44 S45 I120 P122L36-Y116 HydrophobicContact CD2-CE1 4.48Å; D38-Y116 PolarHBondContact OD1-OH 2.96Å; G42-Y116 WeakPolarHBondContact O-CE2 3.43Å; N43-Y116 HydrophobicContact CB-CD2 4.37Å; N43-Y116 PolarHBondContact O-N 2.76Å; Q44-Y116 VanDerWaalsContact C-CZ 3.49Å; Q44-Y116 PolarHBondContact O-OH 2.96Å; S45-Y116 WeakPolarHBondContact CB-OH 3.48Å; Y116-I120 CarbonylContact C-O 3.56Å; Y116-I120 WeakPolarHBondContact CA-O 3.37Å; Y116-P122 HydrophobicContact CD1-CG 4.5Å; Y116-P122 VanDerWaalsContact CE1-CD 3.42Å; Y116-P122 HydrophobicContact CE1-CG 3.84Å; Y116-P122 HydrophobicContact CE2-CG 3.98Å
117T91.7Very high91.8Very high66 Ų6636.4 Ų36.441%0.40520%0.204SC..  trans-129.7-178.6174.1740000109.6N115 E119 I120N115-T117 PolarHBondContact O-N 2.81Å; T117-E119 WeakPolarHBondContact CB-OE2 3.3Å; T117-E119 PolarHBondContact O-N 3.49Å; T117-E119 PolarHBondContact OG1-N 2.76Å; T117-E119 PolarHBondContact OG1-OE2 2.89Å; T117-I120 PolarHBondContact N-O 2.99Å; T117-I120 CarbonylContact O-C 3.58Å; T117-I120 VanDerWaalsContact O-O 3.12Å; T117-I120 PolarHBondContact OG1-N 3.17Å; T117-I120 VanDerWaalsContact OG1-N 3.14Å
118E89.3Confident91.1Very high154 Ų15442.8 Ų42.872%0.7223%0.232SC*.SBendtrans-63.8-28.1173.5-64.4-17417900111.9
119E92.8Very high90.2Very high53 Ų5349.1 Ų49.125%0.24826%0.261CS..SBendtrans-95.2-20.1-178.4-54.182.9-176.400113.9N14 P17 A82 T117N14-E119 WeakPolarHBondContact OD1-CG 3.3Å; P17-E119 VanDerWaalsContact CA-O 3.29Å; P17-E119 WeakPolarHBondContact CA-O 3.49Å; P17-E119 WeakPolarHBondContact CB-O 3.27Å; A82-E119 HydrophobicContact CB-CB 3.69Å; A82-E119 HydrophobicContact CB-CG 3.52Å; T117-E119 WeakPolarHBondContact CB-OE2 3.3Å; T117-E119 PolarHBondContact O-N 3.49Å; T117-E119 PolarHBondContact OG1-N 2.76Å; T117-E119 PolarHBondContact OG1-OE2 2.89Å
120I95Very high89.4Confident2 Ų249.1 Ų49.11%0.0126%0.262CS..  trans-132109.1-178.5-56.2175.7000109.8P17 L36 L71 V84 V114 Y116 T117P17-I120 WeakPolarHBondContact O-CA 3.35Å; L36-I120 HydrophobicContact CD2-CG2 3.86Å; L71-I120 HydrophobicContact CB-CD1 3.84Å; L71-I120 HydrophobicContact CB-CG1 4.18Å; L71-I120 HydrophobicContact CB-CG2 4.26Å; V84-I120 HydrophobicContact CB-CD1 3.63Å; V84-I120 HydrophobicContact CG2-CD1 3.37Å; V114-I120 HydrophobicContact CG1-CB 4.5Å; V114-I120 HydrophobicContact CG1-CD1 3.96Å; V114-I120 HydrophobicContact CG1-CG2 3.77Å; Y116-I120 CarbonylContact C-O 3.56Å; Y116-I120 WeakPolarHBondContact CA-O 3.37Å; T117-I120 PolarHBondContact N-O 2.99Å; T117-I120 CarbonylContact O-C 3.58Å; T117-I120 VanDerWaalsContact O-O 3.12Å; T117-I120 PolarHBondContact OG1-N 3.17Å; T117-I120 VanDerWaalsContact OG1-N 3.14Å
121S94.2Very high88.3Confident36 Ų3650.7 Ų50.725%0.25227%0.272SS..  trans-155148.5173.961.40000110.6P17 W18P17-S121 CarbonylContact C-O 3.58Å; P17-S121 VanDerWaalsContact C-O 3.3Å; P17-S121 WeakPolarHBondContact CB-OG 2.87Å; P17-S121 WeakPolarHBondContact CG-OG 3.26Å; P17-S121 PolarHBondContact O-N 2.57Å; W18-S121 WeakPolarHBondContact CA-O 3.38Å; W18-S121 VanDerWaalsContact CB-O 3.27Å; W18-S121 WeakPolarHBondContact CB-O 3.47Å; W18-S121 PolarHBondContact N-O 3.22Å; W18-S121 VanDerWaalsContact N-O 3.15Å
122P96.3Very high87.3Confident27 Ų2754.6 Ų54.618%0.17529%0.288CS..PPolyproline II helixtrans-77.6154-170.731.9-37.5000112.7L36 V37 D38 Y116L36-P122 HydrophobicContact CD2-CB 4.42Å; L36-P122 HydrophobicContact CG-CB 4.31Å; L36-P122 VanDerWaalsContact O-CA 3.25Å; L36-P122 WeakPolarHBondContact O-CA 3.34Å; V37-P122 VanDerWaalsContact C-CB 3.49Å; D38-P122 HydrophobicContact CB-CB 4.03Å; D38-P122 HydrophobicContact CB-CG 3.78Å; D38-P122 VanDerWaalsContact N-CB 3.29Å; Y116-P122 HydrophobicContact CD1-CG 4.5Å; Y116-P122 VanDerWaalsContact CE1-CD 3.42Å; Y116-P122 HydrophobicContact CE1-CG 3.84Å; Y116-P122 HydrophobicContact CE2-CG 3.98Å
123I95.7Very high86.1Confident4 Ų458.5 Ų58.52%0.02130%0.299CS..BIsolated β-bridgetrans-88.1151.1168.7-166.7163.9000111.3W18 F35 L36 V37 F161 Y168 A170W18-I123 HydrophobicContact CB-CB 3.84Å; W18-I123 HydrophobicContact CB-CG2 4.19Å; W18-I123 HydrophobicContact CD2-CB 3.84Å; W18-I123 HydrophobicContact CD2-CD1 4.07Å; W18-I123 HydrophobicContact CD2-CG1 4.23Å; W18-I123 HydrophobicContact CE3-CB 4.19Å; W18-I123 HydrophobicContact CG-CB 3.67Å; W18-I123 HydrophobicContact CG-CD1 4.3Å; W18-I123 HydrophobicContact CG-CG1 4.45Å; W18-I123 HydrophobicContact CG-CG2 4.23Å; W18-I123 HydrophobicContact CZ2-CD1 4.16Å; F35-I123 HydrophobicContact CB-CG2 4.4Å; F35-I123 HydrophobicContact CD2-CG2 3.58Å; F35-I123 HydrophobicContact CE2-CG2 4.29Å; F35-I123 HydrophobicContact CG-CG2 4.35Å; L36-I123 PolarHBondContact O-N 2.96Å; V37-I123 HydrophobicContact CG1-CG2 4.34Å; I123-F161 HydrophobicContact CD1-CB 3.5Å; I123-F161 HydrophobicContact CD1-CG 4.2Å; I123-Y168 WeakPolarHBondContact CG1-O 3.33Å; I123-A170 HydrophobicContact CD1-CB 3.99Å; I123-A170 HydrophobicContact CG1-CB 4.29Å; I123-A170 HydrophobicContact CG2-CB 3.84Å
124C92.9Very high84.2Confident45 Ų4564.7 Ų64.730%0.30433%0.329SS..BIsolated β-bridgetrans-72.6140.4178-58.10000111.8Y168 F169 A170C124-Y168 WeakPolarHBondContact CB-O 3.43Å; C124-Y168 PolarHBondContact N-O 2.91Å; C124-F169 HydrophobicContact CB-CD1 3.35Å; C124-F169 HydrophobicContact CB-CE1 3.46Å; C124-F169 VanDerWaalsContact CB-CE1 3.46Å; C124-F169 HydrophobicContact CB-CG 3.92Å; C124-F169 HydrophobicContact CB-CZ 4.11Å; C124-F169 WeakPolarHBondContact O-CA 3.23Å; C124-A170 PolarHBondContact O-N 3.35Å
125L92.2Very high82.8Confident26 Ų2667.4 Ų67.414%0.13634%0.343CS..PPolyproline II helixtrans-75.5137.6168.7-68.8174.6000110.8V37 I49 F169 M194 I201 L202V37-L125 HydrophobicContact CB-CD2 4.34Å; V37-L125 HydrophobicContact CG1-CD2 3.87Å; V37-L125 HydrophobicContact CG1-CG 4.48Å; I49-L125 HydrophobicContact CD1-CD2 4.1Å; L125-F169 WeakPolarHBondContact O-CD1 3.38Å; L125-M194 HydrophobicContact CD2-CE 3.8Å; L125-I201 HydrophobicContact CD1-CG2 3.64Å; L125-I201 HydrophobicContact CD2-CD1 4.17Å; L125-I201 HydrophobicContact CD2-CG2 4.22Å; L125-L202 HydrophobicContact CD1-CD2 4.3Å
126P87Confident81.3Confident0 Ų070.3 Ų70.30%036%0.358CS..PPolyproline II helixtrans-78.4152177.233.7-36.2000111.1T131 A170 L171 M194 D195 H198P126-T131 HydrophobicContact CB-CG2 4.46Å; P126-A170 WeakPolarHBondContact CD-O 3.27Å; P126-A170 WeakPolarHBondContact CG-O 2.96Å; P126-L171 HydrophobicContact CB-CD2 3.63Å; P126-L171 HydrophobicContact CG-CD2 4.31Å; P126-M194 HydrophobicContact CG-CB 3.51Å; P126-D195 HydrophobicContact CG-CB 4.47Å; P126-H198 PolarHBondContact O-ND1 2.68Å
127T82.6Confident80.5Confident51 Ų5176.1 Ų76.131%0.31339%0.385SS..  trans-111.3166.7166.167.10000109.2H129 T130 T131T127-H129 PolarHBondContact O-N 2.9Å; T127-H129 VanDerWaalsContact O-N 3.11Å; T127-H129 PolarHBondContact OG1-N 3.44Å; T127-T130 PolarHBondContact N-OG1 2.79Å; T127-T130 WeakPolarHBondContact O-CA 3.24Å; T127-T130 VanDerWaalsContact O-CB 3.29Å; T127-T130 WeakPolarHBondContact O-CB 3.45Å; T127-T130 PolarHBondContact O-N 3.45Å; T127-T130 PolarHBondContact OG1-N 3.39Å; T127-T130 PolarHBondContact OG1-OG1 3.32Å; T127-T131 PolarHBondContact O-N 2.95Å; T127-T131 PolarHBondContact O-OG1 3.07Å
128K78.5Confident80.3Confident135 Ų13575.2 Ų75.259%0.58738%0.38SS*.Hα-helixtrans-56-27171.7-67.6-172.6177-178.60113.5T131 N132K128-T131 WeakPolarHBondContact CA-OG1 3.38Å; K128-T131 PolarHBondContact O-OG1 3.31Å; K128-N132 WeakPolarHBondContact O-CB 3.29Å; K128-N132 PolarHBondContact O-N 2.9Å; K128-N132 PolarHBondContact O-ND2 3.17Å
129H76.4Confident80.3Confident133 Ų13371.8 Ų71.862%0.61636%0.363SS*.Hα-helixtrans-70.9-36.1174.2-175.3-56.3000111.5T127T127-H129 PolarHBondContact O-N 2.9Å; T127-H129 VanDerWaalsContact O-N 3.11Å; T127-H129 PolarHBondContact OG1-N 3.44Å
130T75.3Confident80Confident15 Ų1571.6 Ų71.69%0.09237%0.371CS..Hα-helixtrans-69.5-40.2-179.8-48.60000111.4T127 I164 F169T127-T130 PolarHBondContact N-OG1 2.79Å; T127-T130 WeakPolarHBondContact O-CA 3.24Å; T127-T130 VanDerWaalsContact O-CB 3.29Å; T127-T130 WeakPolarHBondContact O-CB 3.45Å; T127-T130 PolarHBondContact O-N 3.45Å; T127-T130 PolarHBondContact OG1-N 3.39Å; T127-T130 PolarHBondContact OG1-OG1 3.32Å; T130-I164 HydrophobicContact CG2-CD1 3.28Å; T130-F169 HydrophobicContact CG2-CB 4.3Å; T130-F169 HydrophobicContact CG2-CD1 3.91Å; T130-F169 HydrophobicContact CG2-CD2 4.11Å; T130-F169 HydrophobicContact CG2-CE1 4.23Å; T130-F169 HydrophobicContact CG2-CE2 4.41Å; T130-F169 HydrophobicContact CG2-CG 3.85Å; T130-F169 HydrophobicContact CG2-CZ 4.47Å
131T69.7Low79.6Confident34 Ų3472.1 Ų72.121%0.20938%0.375CS..Hα-helixtrans-80.7-23.2-177.835.90000115.2P126 T127 K128 R133 L171 D195P126-T131 HydrophobicContact CB-CG2 4.46Å; T127-T131 PolarHBondContact O-N 2.95Å; T127-T131 PolarHBondContact O-OG1 3.07Å; K128-T131 WeakPolarHBondContact CA-OG1 3.38Å; K128-T131 PolarHBondContact O-OG1 3.31Å; T131-R133 PolarHBondContact O-N 2.92Å; T131-L171 HydrophobicContact CG2-CD1 4.45Å; T131-L171 HydrophobicContact CG2-CD2 3.91Å; T131-D195 WeakPolarHBondContact CB-OD2 3.48Å; T131-D195 HydrophobicContact CG2-CB 3.79Å; T131-D195 WeakPolarHBondContact OG1-CB 3.32Å; T131-D195 VanDerWaalsContact OG1-CG 3.3Å; T131-D195 PolarHBondContact OG1-OD2 3.07Å
132N66.4Low79.2Confident138 Ų13871.3 Ų71.374%0.73837%0.373SS*.THydrogen-bonded Turntrans-71.9-4.7179.4-80.6-14.5000114.6K128K128-N132 WeakPolarHBondContact O-CB 3.29Å; K128-N132 PolarHBondContact O-N 2.9Å; K128-N132 PolarHBondContact O-ND2 3.17Å
133R64Low78.6Confident109 Ų10973 Ų7341%0.41138%0.375SS..SBendtrans-83.3128.3173.2-67.5-175.3174.6176.52.6108.7T131 L135 D165T131-R133 PolarHBondContact O-N 2.92Å; R133-L135 WeakPolarHBondContact O-CG 3.29Å; R133-L135 PolarHBondContact O-N 2.95Å; R133-L135 VanDerWaalsContact O-N 3.13Å; R133-D165 IonicContact CZ-OD2 3.34Å; R133-D165 VanDerWaalsContact NH1-CG 3.3Å; R133-D165 IonicContact NH1-OD1 3.55Å; R133-D165 PolarHBondContact NH1-OD1 3.44Å; R133-D165 VanDerWaalsContact NH1-OD1 3.15Å; R133-D165 IonicContact NH1-OD2 3.17Å; R133-D165 PolarHBondContact NH1-OD2 2.83Å; R133-D165 IonicContact NH2-OD2 2.87Å
134L48.5Very low77.7Confident174 Ų17473.1 Ų73.191%0.91138%0.378SS*.  trans-57.6115.4169.4-88.6138.5000108.4
135L64.7Low76.3Confident60 Ų6076 Ų7631%0.31439%0.386SS..  trans-108.7118.1179.3-68.9162.7000108.4R133 C162 I164 L171R133-L135 WeakPolarHBondContact O-CG 3.29Å; R133-L135 PolarHBondContact O-N 2.95Å; R133-L135 VanDerWaalsContact O-N 3.13Å; L135-C162 HydrophobicContact CD1-CB 4.16Å; L135-I164 HydrophobicContact CD1-CD1 3.99Å; L135-I164 HydrophobicContact CD2-CD1 4.21Å; L135-I164 HydrophobicContact CD2-CG1 3.91Å; L135-L171 HydrophobicContact CD1-CD1 3.39Å
136D61.4Low74.8Confident155 Ų15577.5 Ų77.583%0.82940%0.396SS*.SBendtrans-74.6-30.8-176.3-70-23.9000112.5
137K76.4Confident72.9Confident182 Ų18285.4 Ų85.479%0.79143%0.433SS*.  trans-149.8129.5-175.4-62-174.9-178.3178.90112.2
138C87.1Confident70.7Confident46 Ų4685.1 Ų85.131%0.31143%0.433SS..  trans-124.3167.3173.1-65.60000109.6L160 C162C138-L160 HydrophobicContact CB-CD1 3.85Å; C138-L160 HydrophobicContact CB-CG 4.24Å; C138-C162 HydrophobicContact CB-CB 4.01Å; C138-C162 WeakPolarHBondContact CB-SG 3.4Å; C138-C162 WeakPolarHBondContact SG-CB 3.2Å; C138-C162 CovalentContact SG-SG 2.02Å; C138-C162 PolarHBondContact SG-SG 3.33Å
139F89.2Confident68.7Low82 Ų8289.3 Ų89.336%0.3645%0.445SS..EExtended strand (participates in β ladder)trans-113.5143.1-177.7-58.3-84.3000110.2W9 F161 Y168W9-F139 HydrophobicContact CZ2-CE1 4.38Å; F139-F161 HydrophobicContact CB-CD1 4.4Å; F139-F161 HydrophobicContact CB-CD2 3.96Å; F139-F161 HydrophobicContact CB-CE1 3.94Å; F139-F161 HydrophobicContact CB-CE2 3.45Å; F139-F161 VanDerWaalsContact CB-CE2 3.45Å; F139-F161 HydrophobicContact CB-CG 4.41Å; F139-F161 HydrophobicContact CB-CZ 3.43Å; F139-F161 VanDerWaalsContact CB-CZ 3.43Å; F139-F161 HydrophobicContact CD2-CD2 4.43Å; F139-F161 HydrophobicContact CD2-CE2 4.17Å; F139-F161 HydrophobicContact CG-CE2 4.07Å; F139-F161 HydrophobicContact CG-CZ 4.39Å; F139-F161 PolarHBondContact N-O 2.95Å; F139-F161 WeakPolarHBondContact O-CD1 3.43Å; F139-F161 PolarHBondContact O-N 2.92Å; F139-Y168 HydrophobicContact CD2-CE1 4.35Å; F139-Y168 HydrophobicContact CE2-CE1 4.31Å
140A86.3Confident66.5Low49 Ų4988.1 Ų88.141%0.40544%0.443SS..EExtended strand (participates in β ladder)trans-116.5146.1164.800000107.9Y191A140-Y191 WeakPolarHBondContact CB-OH 3.21Å
141A87.3Confident64.6Low13 Ų1388.1 Ų88.111%0.10745%0.445CS..  trans-147.4149.2179.600000110.4L16 M19 S158 F161L16-A141 HydrophobicContact CD1-CB 3.63Å; M19-A141 HydrophobicContact CE-CB 4.19Å; M19-A141 WeakPolarHBondContact CE-O 3.33Å; M19-A141 HydrophobicContact SD-CB 4.23Å; A141-S158 VanDerWaalsContact O-CB 3.25Å; A141-S158 WeakPolarHBondContact O-CB 3.1Å; A141-F161 HydrophobicContact CB-CE1 3.82Å; A141-F161 HydrophobicContact CB-CZ 4.17Å
142G86.3Confident63.4Low19 Ų1988.8 Ų88.820%0.19645%0.445CS..  trans-178.4-175.6-178.600000112.8D155G142-D155 VanDerWaalsContact C-OD1 3.23Å; G142-D155 WeakPolarHBondContact CA-OD1 3.48Å
143W83.5Confident62.9Low62 Ų6286.1 Ų86.124%0.23543%0.428CS..  trans-123.219.2-178.2-66-83.5000112.6M19 Y21 A73 H74 M76 D155M19-W143 HydrophobicContact CB-CH2 3.45Å; M19-W143 VanDerWaalsContact CB-CH2 3.45Å; M19-W143 HydrophobicContact CB-CZ2 4.28Å; M19-W143 HydrophobicContact CB-CZ3 4.02Å; M19-W143 HydrophobicContact CE-CE3 4.29Å; M19-W143 HydrophobicContact CE-CH2 4.26Å; M19-W143 HydrophobicContact CE-CZ3 3.79Å; M19-W143 HydrophobicContact CG-CH2 4.44Å; Y21-W143 HydrophobicContact CD2-CD2 4.49Å; Y21-W143 HydrophobicContact CD2-CE3 4.15Å; A73-W143 WeakPolarHBondContact O-CZ2 3.49Å; H74-W143 PolarHBondContact O-NE1 2.92Å; M76-W143 HydrophobicContact CG-CD2 4.18Å; M76-W143 HydrophobicContact CG-CG 3.9Å; W143-D155 PolarHBondContact N-OD1 3.38Å
144G75.4Confident63.2Low8 Ų881.2 Ų81.28%0.08241%0.411CS..  trans-63.6170.2-177.200000115D155G144-D155 WeakPolarHBondContact CA-OD1 3.31Å; G144-D155 WeakPolarHBondContact CA-OD2 3.2Å; G144-D155 VanDerWaalsContact N-CG 3.34Å; G144-D155 PolarHBondContact N-OD1 2.89Å; G144-D155 PolarHBondContact N-OD2 2.77Å
145K64.8Low64.7Low106 Ų10673.8 Ų73.846%0.46137%0.372SS..  trans-70.8139.2-176.8-66.3179-177.5170.70112.2S148 Q153K145-S148 WeakPolarHBondContact CB-OG 3.17Å; K145-S148 VanDerWaalsContact CD-OG 3.26Å; K145-S148 WeakPolarHBondContact CD-OG 3.39Å; K145-Q153 HydrophobicContact CD-CB 4.34Å; K145-Q153 PolarHBondContact N-O 3Å
146T60.2Low65.8Low57 Ų5771.9 Ų71.935%0.3536%0.364SS..SBendtrans-96.5-27.1-178.647.90000115.9R4R4-T146 HydrophobicContact CB-CG2 4.15Å; R4-T146 HydrophobicContact CG-CG2 3.75Å; R4-T146 VanDerWaalsContact N-CG2 3.29Å
147E47.9Very low67.2Low166 Ų16664.5 Ų64.578%0.77632%0.324SS*.SBendtrans-127.36.1-165-69.7-174.6169.400114.2
148S35.5Very low68Low45 Ų4556 Ų5632%0.31529%0.287SS..SBendtrans-97.7143.817658.20000111.8K145 L150K145-S148 WeakPolarHBondContact CB-OG 3.17Å; K145-S148 VanDerWaalsContact CD-OG 3.26Å; K145-S148 WeakPolarHBondContact CD-OG 3.39Å; S148-L150 CarbonylContact O-C 3.54Å; S148-L150 PolarHBondContact O-N 2.86Å; S148-L150 PolarHBondContact OG-O 3.36Å
149R35.7Very low68.3Low222 Ų22253.8 Ų53.884%0.83827%0.273SS*.SBendtrans-58.521.1171.6-74.4-179167.2165-4115.5N180R149-N180 PolarHBondContact O-OD1 3.08Å
150L31.6Very low68.5Low108 Ų10852 Ų5257%0.56527%0.267SS*.SBendtrans-148.382.4176-66.8172.4000106.1S148 F152S148-L150 CarbonylContact O-C 3.54Å; S148-L150 PolarHBondContact O-N 2.86Å; S148-L150 PolarHBondContact OG-O 3.36Å; L150-F152 VanDerWaalsContact C-N 3.34Å; L150-F152 PolarHBondContact O-N 2.94Å
151A35.2Very low68.8Low16 Ų1650 Ų5013%0.13225%0.249CC..THydrogen-bonded Turntrans-86.720.3-164.200000115.9A179 C181A151-A179 PolarHBondContact N-O 3.08Å; A151-C181 HydrophobicContact CB-CB 4.25Å
152F44.3Very low68.9Low48 Ų4849.3 Ų49.321%0.21124%0.244CC..THydrogen-bonded Turntrans-122.1-1.4177.7-78.8-70.4000115.3L150 G154 D155 L174 P178 C181L150-F152 VanDerWaalsContact C-N 3.34Å; L150-F152 PolarHBondContact O-N 2.94Å; F152-G154 PolarHBondContact O-N 3.09Å; F152-D155 PolarHBondContact O-N 2.92Å; F152-L174 HydrophobicContact CD1-CD2 4.02Å; F152-L174 HydrophobicContact CE1-CD2 4.13Å; F152-P178 VanDerWaalsContact CD2-O 3.25Å; F152-P178 WeakPolarHBondContact CD2-O 3.28Å; F152-P178 HydrophobicContact CE2-CG 4.17Å; F152-P178 WeakPolarHBondContact CE2-O 3.12Å; F152-C181 WeakPolarHBondContact CE2-SG 3.18Å; F152-C181 WeakPolarHBondContact CZ-SG 3.28Å
153Q56.1Low69Low82 Ų8253.2 Ų53.238%0.38326%0.256SS..THydrogen-bonded Turntrans-71.2108.4-178.1-154.4168.721.800109.8K145K145-Q153 HydrophobicContact CD-CB 4.34Å; K145-Q153 PolarHBondContact N-O 3Å
154G69.5Low69Low5 Ų550.8 Ų50.85%0.05225%0.248CC..THydrogen-bonded Turntrans125.5-31.9-17700000114.9S31 C32 A33 F152S31-G154 VanDerWaalsContact O-CA 3.26Å; S31-G154 WeakPolarHBondContact O-CA 3.34Å; C32-G154 CarbonylContact C-O 3.58Å; A33-G154 PolarHBondContact N-O 2.92Å; F152-G154 PolarHBondContact O-N 3.09Å
155D80Confident69.4Low18 Ų1856.7 Ų56.710%0.09628%0.278CS..THydrogen-bonded Turntrans-96.2-11.8-171.1-70.8-29.5000114.6G142 W143 G144 F152 G157 S158 L174G142-D155 VanDerWaalsContact C-OD1 3.23Å; G142-D155 WeakPolarHBondContact CA-OD1 3.48Å; W143-D155 PolarHBondContact N-OD1 3.38Å; G144-D155 WeakPolarHBondContact CA-OD1 3.31Å; G144-D155 WeakPolarHBondContact CA-OD2 3.2Å; G144-D155 VanDerWaalsContact N-CG 3.34Å; G144-D155 PolarHBondContact N-OD1 2.89Å; G144-D155 PolarHBondContact N-OD2 2.77Å; F152-D155 PolarHBondContact O-N 2.92Å; D155-G157 PolarHBondContact O-N 2.95Å; D155-S158 WeakPolarHBondContact O-CB 3.36Å; D155-S158 PolarHBondContact O-N 3.19Å; D155-S158 PolarHBondContact O-OG 2.82Å; D155-L174 HydrophobicContact CB-CD2 3.89Å; D155-L174 WeakPolarHBondContact O-CD2 3.33Å
156S87.8Confident70.2Confident20 Ų2054.3 Ų54.314%0.1428%0.284CS..THydrogen-bonded Turntrans-49.6131.1174.8-69.40000111.3C32 A33 H53C32-S156 WeakPolarHBondContact CB-O 3.44Å; A33-S156 PolarHBondContact N-O 3Å; A33-S156 VanDerWaalsContact O-O 3.12Å; H53-S156 VanDerWaalsContact CE1-CB 3.49Å; H53-S156 WeakPolarHBondContact CE1-CB 3.5Å; H53-S156 PolarHBondContact CE1-OG 2.61Å; H53-S156 WeakPolarHBondContact NE2-CB 3.42Å; H53-S156 PolarHBondContact NE2-OG 2.95Å
157G92.1Very high71.6Confident0 Ų059.5 Ų59.50%030%0.297CS..THydrogen-bonded Turntrans87.5-3.9-176.400000115.7A33 D155 L174A33-G157 CarbonylContact O-C 3.6Å; A33-G157 VanDerWaalsContact O-C 3.31Å; A33-G157 WeakPolarHBondContact O-CA 3.25Å; D155-G157 PolarHBondContact O-N 2.95Å; G157-L174 PolarHBondContact N-O 3.06Å
158S92.2Very high73.7Confident3 Ų355.1 Ų55.12%0.02127%0.274CS..PPolyproline II helixtrans-65.2152.2176560000113A141 D155 V173 L174A141-S158 VanDerWaalsContact O-CB 3.25Å; A141-S158 WeakPolarHBondContact O-CB 3.1Å; D155-S158 WeakPolarHBondContact O-CB 3.36Å; D155-S158 PolarHBondContact O-N 3.19Å; D155-S158 PolarHBondContact O-OG 2.82Å; S158-V173 WeakPolarHBondContact O-CA 3.35Å; S158-L174 PolarHBondContact O-N 3.34Å; S158-L174 WeakPolarHBondContact OG-CB 3.35Å
159P94.1Very high76.4Confident0 Ų054.6 Ų54.60%027%0.266CS..EExtended strand (participates in β ladder)trans-79.5138.8178.230-30.3000112.3M19 F35 F161 A170 G172M19-P159 HydrophobicContact SD-CG 3.83Å; F35-P159 HydrophobicContact CB-CB 4.4Å; F35-P159 HydrophobicContact CB-CG 4.01Å; F35-P159 HydrophobicContact CD1-CB 3.52Å; F35-P159 HydrophobicContact CD1-CG 3.8Å; F35-P159 HydrophobicContact CE1-CB 3.8Å; F35-P159 HydrophobicContact CG-CB 3.89Å; F35-P159 HydrophobicContact CG-CG 4.04Å; F35-P159 HydrophobicContact CZ-CB 4.4Å; P159-F161 HydrophobicContact CB-CD1 4.27Å; P159-F161 HydrophobicContact CG-CD1 4.03Å; P159-F161 WeakPolarHBondContact O-CD1 3.48Å; P159-A170 HydrophobicContact CB-CB 4.27Å; P159-G172 CarbonylContact C-O 3.53Å; P159-G172 VanDerWaalsContact CA-O 3.29Å; P159-G172 WeakPolarHBondContact CA-O 3.27Å
160L91.9Very high79.2Confident46 Ų4644 Ų4424%0.24123%0.226CC..EExtended strand (participates in β ladder)trans-83.9118.4150.1-18070.1000107.5C138 A170 L171 G172 Y191C138-L160 HydrophobicContact CB-CD1 3.85Å; C138-L160 HydrophobicContact CB-CG 4.24Å; L160-A170 CarbonylContact O-C 3.59Å; L160-L171 PolarHBondContact O-N 3.34Å; L160-G172 PolarHBondContact N-O 2.94Å; L160-G172 PolarHBondContact O-N 2.87Å; L160-Y191 HydrophobicContact CB-CD1 3.51Å; L160-Y191 HydrophobicContact CB-CE1 3.59Å; L160-Y191 HydrophobicContact CB-CG 4.01Å; L160-Y191 HydrophobicContact CD2-CD2 4.49Å; L160-Y191 HydrophobicContact CD2-CG 4.4Å
161F93.2Very high82.1Confident5 Ų539.8 Ų39.82%0.02220%0.204CC..EExtended strand (participates in β ladder)trans-129.9144.6-175.361.1-82.9000113.5L16 W18 I123 F139 A141 P159 Y168 F169L16-F161 HydrophobicContact CD1-CZ 4.16Å; L16-F161 HydrophobicContact CD2-CE2 3.6Å; L16-F161 HydrophobicContact CD2-CZ 3.48Å; L16-F161 VanDerWaalsContact CD2-CZ 3.48Å; L16-F161 HydrophobicContact CG-CZ 4.48Å; W18-F161 AromaticContact CZ2-CD2 3.83Å; W18-F161 HydrophobicContact CZ2-CD2 3.83Å; W18-F161 AromaticContact CZ2-CE2 3.87Å; W18-F161 HydrophobicContact CZ2-CE2 3.87Å; W18-F161 HydrophobicContact CZ2-CG 4.41Å; W18-F161 HydrophobicContact CZ2-CZ 4.48Å; I123-F161 HydrophobicContact CD1-CB 3.5Å; I123-F161 HydrophobicContact CD1-CG 4.2Å; F139-F161 HydrophobicContact CB-CD1 4.4Å; F139-F161 HydrophobicContact CB-CD2 3.96Å; F139-F161 HydrophobicContact CB-CE1 3.94Å; F139-F161 HydrophobicContact CB-CE2 3.45Å; F139-F161 VanDerWaalsContact CB-CE2 3.45Å; F139-F161 HydrophobicContact CB-CG 4.41Å; F139-F161 HydrophobicContact CB-CZ 3.43Å; F139-F161 VanDerWaalsContact CB-CZ 3.43Å; F139-F161 HydrophobicContact CD2-CD2 4.43Å; F139-F161 HydrophobicContact CD2-CE2 4.17Å; F139-F161 HydrophobicContact CG-CE2 4.07Å; F139-F161 HydrophobicContact CG-CZ 4.39Å; F139-F161 PolarHBondContact N-O 2.95Å; F139-F161 WeakPolarHBondContact O-CD1 3.43Å; F139-F161 PolarHBondContact O-N 2.92Å; A141-F161 HydrophobicContact CB-CE1 3.82Å; A141-F161 HydrophobicContact CB-CZ 4.17Å; P159-F161 HydrophobicContact CB-CD1 4.27Å; P159-F161 HydrophobicContact CG-CD1 4.03Å; P159-F161 WeakPolarHBondContact O-CD1 3.48Å; F161-Y168 AromaticContact CD2-CD1 3.81Å; F161-Y168 HydrophobicContact CD2-CD1 3.81Å; F161-Y168 HydrophobicContact CD2-CE1 4.37Å; F161-Y168 HydrophobicContact CE2-CD1 4.35Å; F161-F169 WeakPolarHBondContact CA-O 3.13Å; F161-F169 WeakPolarHBondContact CB-O 3.49Å
162C90.2Very high84.8Confident0 Ų039 Ų390%020%0.198CC..EExtended strand (participates in β ladder)trans-135.4147.1-176.9-32.60000110.2L135 C138 Y168 F169 L171L135-C162 HydrophobicContact CD1-CB 4.16Å; C138-C162 HydrophobicContact CB-CB 4.01Å; C138-C162 WeakPolarHBondContact CB-SG 3.4Å; C138-C162 WeakPolarHBondContact SG-CB 3.2Å; C138-C162 CovalentContact SG-SG 2.02Å; C138-C162 PolarHBondContact SG-SG 3.33Å; C162-Y168 WeakPolarHBondContact O-CA 3.5Å; C162-F169 PolarHBondContact N-O 2.82Å; C162-F169 VanDerWaalsContact N-O 3.07Å; C162-F169 PolarHBondContact O-N 3.32Å; C162-L171 HydrophobicContact CB-CD1 4.26Å; C162-L171 WeakPolarHBondContact SG-CD1 3.24Å
163E87.1Confident87.1Confident100 Ų10036.8 Ų36.847%0.46719%0.188SC..EExtended strand (participates in β ladder)trans-83124.7173-166.2177.2161.300110R167 Y168E163-R167 CarbonylContact C-O 3.56Å; E163-R167 WeakPolarHBondContact CA-O 3.1Å; E163-Y168 HydrophobicContact CB-CD1 3.99Å; E163-Y168 HydrophobicContact CB-CE1 3.59Å; E163-Y168 HydrophobicContact CG-CE1 4.2Å; E163-Y168 HydrophobicContact CG-CE2 4.28Å; E163-Y168 PolarHBondContact OE2-OH 3.33Å
164I84.8Confident88.7Confident12 Ų1233.1 Ų33.16%0.06217%0.171CC..EExtended strand (participates in β ladder)trans-135.4117.7-179.9-54.3172.5000106.8T130 L135 G166 R167 F169T130-I164 HydrophobicContact CG2-CD1 3.28Å; L135-I164 HydrophobicContact CD1-CD1 3.99Å; L135-I164 HydrophobicContact CD2-CD1 4.21Å; L135-I164 HydrophobicContact CD2-CG1 3.91Å; I164-G166 PolarHBondContact O-N 3.24Å; I164-R167 PolarHBondContact N-O 3.42Å; I164-R167 PolarHBondContact O-N 3.05Å; I164-R167 VanDerWaalsContact O-N 3.11Å; I164-F169 HydrophobicContact CB-CD2 3.87Å; I164-F169 HydrophobicContact CB-CE2 3.98Å; I164-F169 HydrophobicContact CD1-CB 4.48Å; I164-F169 HydrophobicContact CD1-CD2 4.12Å; I164-F169 HydrophobicContact CG1-CD2 4.24Å
165D82.1Confident89.5Confident131 Ų13133.4 Ų33.470%0.70117%0.172SC*.THydrogen-bonded Turntrans52.840-179.1-56.3-27000113.3R133R133-D165 IonicContact CZ-OD2 3.34Å; R133-D165 VanDerWaalsContact NH1-CG 3.3Å; R133-D165 IonicContact NH1-OD1 3.55Å; R133-D165 PolarHBondContact NH1-OD1 3.44Å; R133-D165 VanDerWaalsContact NH1-OD1 3.15Å; R133-D165 IonicContact NH1-OD2 3.17Å; R133-D165 PolarHBondContact NH1-OD2 2.83Å; R133-D165 IonicContact NH2-OD2 2.87Å
166G83.4Confident89.4Confident57 Ų5736 Ų3659%0.58819%0.186SC*.THydrogen-bonded Turntrans78.112.6178.400000115.1I164I164-G166 PolarHBondContact O-N 3.24Å
167R88.4Confident88.4Confident165 Ų16536.3 Ų36.362%0.62319%0.192SC*.EExtended strand (participates in β ladder)trans-128.7146.2175.1-63.1-175.5-176.8-1730.7111.1E163 I164 F169E163-R167 CarbonylContact C-O 3.56Å; E163-R167 WeakPolarHBondContact CA-O 3.1Å; I164-R167 PolarHBondContact N-O 3.42Å; I164-R167 PolarHBondContact O-N 3.05Å; I164-R167 VanDerWaalsContact O-N 3.11Å; R167-F169 HydrophobicContact CB-CE2 3.87Å; R167-F169 HydrophobicContact CB-CZ 4.47Å; R167-F169 WeakPolarHBondContact O-CD2 3.3Å
168Y92.3Very high86.8Confident75 Ų7537 Ų3729%0.29420%0.196SC..EExtended strand (participates in β ladder)trans-90.1133.5176.3-70-84000111.5W18 I123 C124 F139 F161 C162 E163W18-Y168 HydrophobicContact CH2-CD1 4.44Å; W18-Y168 AromaticContact CH2-CD2 3.81Å; W18-Y168 HydrophobicContact CH2-CD2 3.81Å; W18-Y168 AromaticContact CH2-CG 3.72Å; W18-Y168 HydrophobicContact CH2-CG 3.72Å; W18-Y168 HydrophobicContact CZ2-CG 4.29Å; W18-Y168 HydrophobicContact CZ3-CD2 4.45Å; I123-Y168 WeakPolarHBondContact CG1-O 3.33Å; C124-Y168 WeakPolarHBondContact CB-O 3.43Å; C124-Y168 PolarHBondContact N-O 2.91Å; F139-Y168 HydrophobicContact CD2-CE1 4.35Å; F139-Y168 HydrophobicContact CE2-CE1 4.31Å; F161-Y168 AromaticContact CD2-CD1 3.81Å; F161-Y168 HydrophobicContact CD2-CD1 3.81Å; F161-Y168 HydrophobicContact CD2-CE1 4.37Å; F161-Y168 HydrophobicContact CE2-CD1 4.35Å; C162-Y168 WeakPolarHBondContact O-CA 3.5Å; E163-Y168 HydrophobicContact CB-CD1 3.99Å; E163-Y168 HydrophobicContact CB-CE1 3.59Å; E163-Y168 HydrophobicContact CG-CE1 4.2Å; E163-Y168 HydrophobicContact CG-CE2 4.28Å; E163-Y168 PolarHBondContact OE2-OH 3.33Å
169F92.7Very high85.1Confident33 Ų3340 Ų4015%0.14522%0.221CC..EExtended strand (participates in β ladder)trans-122.1137177.6-68.3-96.2000110.7C124 L125 T130 F161 C162 I164 R167 L171C124-F169 HydrophobicContact CB-CD1 3.35Å; C124-F169 HydrophobicContact CB-CE1 3.46Å; C124-F169 VanDerWaalsContact CB-CE1 3.46Å; C124-F169 HydrophobicContact CB-CG 3.92Å; C124-F169 HydrophobicContact CB-CZ 4.11Å; C124-F169 WeakPolarHBondContact O-CA 3.23Å; L125-F169 WeakPolarHBondContact O-CD1 3.38Å; T130-F169 HydrophobicContact CG2-CB 4.3Å; T130-F169 HydrophobicContact CG2-CD1 3.91Å; T130-F169 HydrophobicContact CG2-CD2 4.11Å; T130-F169 HydrophobicContact CG2-CE1 4.23Å; T130-F169 HydrophobicContact CG2-CE2 4.41Å; T130-F169 HydrophobicContact CG2-CG 3.85Å; T130-F169 HydrophobicContact CG2-CZ 4.47Å; F161-F169 WeakPolarHBondContact CA-O 3.13Å; F161-F169 WeakPolarHBondContact CB-O 3.49Å; C162-F169 PolarHBondContact N-O 2.82Å; C162-F169 VanDerWaalsContact N-O 3.07Å; C162-F169 PolarHBondContact O-N 3.32Å; I164-F169 HydrophobicContact CB-CD2 3.87Å; I164-F169 HydrophobicContact CB-CE2 3.98Å; I164-F169 HydrophobicContact CD1-CB 4.48Å; I164-F169 HydrophobicContact CD1-CD2 4.12Å; I164-F169 HydrophobicContact CG1-CD2 4.24Å; R167-F169 HydrophobicContact CB-CE2 3.87Å; R167-F169 HydrophobicContact CB-CZ 4.47Å; R167-F169 WeakPolarHBondContact O-CD2 3.3Å; F169-L171 HydrophobicContact CB-CD2 4.1Å; F169-L171 PolarHBondContact O-N 3.02Å
170A94.4Very high83.4Confident0 Ų042.5 Ų42.50%024%0.235CC..EExtended strand (participates in β ladder)trans-83.195175.200000110.7F35 I123 C124 P126 P159 L160 M194F35-A170 HydrophobicContact CD2-CB 4.08Å; F35-A170 HydrophobicContact CE2-CB 3.6Å; F35-A170 HydrophobicContact CZ-CB 4.02Å; I123-A170 HydrophobicContact CD1-CB 3.99Å; I123-A170 HydrophobicContact CG1-CB 4.29Å; I123-A170 HydrophobicContact CG2-CB 3.84Å; C124-A170 PolarHBondContact O-N 3.35Å; P126-A170 WeakPolarHBondContact CD-O 3.27Å; P126-A170 WeakPolarHBondContact CG-O 2.96Å; P159-A170 HydrophobicContact CB-CB 4.27Å; L160-A170 CarbonylContact O-C 3.59Å; A170-M194 VanDerWaalsContact O-CB 3.3Å; A170-M194 WeakPolarHBondContact O-CB 3.37Å; A170-M194 WeakPolarHBondContact O-CG 3.32Å
171L91.4Very high81.8Confident19 Ų1941.1 Ų41.110%0.09923%0.229CC..EExtended strand (participates in β ladder)trans-78.4-22.2-178-59.6-162.3000114P126 T131 L135 L160 C162 F169 M194P126-L171 HydrophobicContact CB-CD2 3.63Å; P126-L171 HydrophobicContact CG-CD2 4.31Å; T131-L171 HydrophobicContact CG2-CD1 4.45Å; T131-L171 HydrophobicContact CG2-CD2 3.91Å; L135-L171 HydrophobicContact CD1-CD1 3.39Å; L160-L171 PolarHBondContact O-N 3.34Å; C162-L171 HydrophobicContact CB-CD1 4.26Å; C162-L171 WeakPolarHBondContact SG-CD1 3.24Å; F169-L171 HydrophobicContact CB-CD2 4.1Å; F169-L171 PolarHBondContact O-N 3.02Å; L171-M194 WeakPolarHBondContact O-CB 3.38Å; L171-M194 PolarHBondContact O-N 3.41Å
172G91.6Very high80Confident1 Ų144.1 Ų44.11%0.0125%0.251CS..EExtended strand (participates in β ladder)trans-151.1160.4-178.500000115.2P159 L160 V192P159-G172 CarbonylContact C-O 3.53Å; P159-G172 VanDerWaalsContact CA-O 3.29Å; P159-G172 WeakPolarHBondContact CA-O 3.27Å; L160-G172 PolarHBondContact N-O 2.94Å; L160-G172 PolarHBondContact O-N 2.87Å; G172-V192 CarbonylContact C-O 3.57Å; G172-V192 WeakPolarHBondContact CA-O 3.4Å
173V93.6Very high78.2Confident0 Ų051.3 Ų51.30%028%0.284CS..EExtended strand (participates in β ladder)trans-113.2125.5169.8-1760000108.4F35 I49 A51 I105 S158 S175 Y191 V192 M194F35-V173 HydrophobicContact CE1-CG2 3.95Å; F35-V173 HydrophobicContact CZ-CG2 3.9Å; I49-V173 HydrophobicContact CG2-CG2 4Å; A51-V173 HydrophobicContact CB-CG1 4.43Å; I105-V173 HydrophobicContact CD1-CG2 4.33Å; I105-V173 HydrophobicContact CG1-CG2 4.47Å; S158-V173 WeakPolarHBondContact O-CA 3.35Å; V173-S175 PolarHBondContact O-N 2.7Å; V173-Y191 CarbonylContact O-C 3.56Å; V173-Y191 WeakPolarHBondContact O-CA 3.48Å; V173-V192 HydrophobicContact CB-CB 4.16Å; V173-V192 PolarHBondContact N-O 3.2Å; V173-V192 VanDerWaalsContact N-O 3.12Å; V173-V192 PolarHBondContact O-N 2.82Å; V173-M194 HydrophobicContact CG2-CG 4.09Å; V173-M194 HydrophobicContact CG2-SD 3.44Å; V173-M194 WeakPolarHBondContact CG2-SD 3.37Å
174L90.6Very high76.5Confident5 Ų550.3 Ų50.33%0.02628%0.279CS..EExtended strand (participates in β ladder)trans-64.1118.5179.2-177.662.9000110.2F152 D155 G157 S158 Y191F152-L174 HydrophobicContact CD1-CD2 4.02Å; F152-L174 HydrophobicContact CE1-CD2 4.13Å; D155-L174 HydrophobicContact CB-CD2 3.89Å; D155-L174 WeakPolarHBondContact O-CD2 3.33Å; G157-L174 PolarHBondContact N-O 3.06Å; S158-L174 PolarHBondContact O-N 3.34Å; S158-L174 WeakPolarHBondContact OG-CB 3.35Å; L174-Y191 HydrophobicContact CB-CD1 4.04Å; L174-Y191 HydrophobicContact CB-CE1 3.64Å; L174-Y191 HydrophobicContact CD1-CD1 4.48Å; L174-Y191 HydrophobicContact CD1-CD2 4.41Å; L174-Y191 HydrophobicContact CD1-CE1 4.02Å; L174-Y191 HydrophobicContact CD1-CE2 3.92Å; L174-Y191 HydrophobicContact CG-CE1 4.39Å; L174-Y191 VanDerWaalsContact N-CD1 3.34Å
175S84.9Confident75Confident11 Ų1159.5 Ų59.58%0.07732%0.322CS..EExtended strand (participates in β ladder)trans-108.1-50.6179.8175.30000111.4H53 D104 V173 F190H53-S175 PolarHBondContact CE1-O 2.83Å; D104-S175 WeakPolarHBondContact CB-OG 3.22Å; D104-S175 WeakPolarHBondContact OD2-CA 3.01Å; D104-S175 VanDerWaalsContact OD2-CB 3.26Å; D104-S175 WeakPolarHBondContact OD2-CB 3.42Å; D104-S175 PolarHBondContact OD2-OG 3.46Å; V173-S175 PolarHBondContact O-N 2.7Å; S175-F190 PolarHBondContact N-O 3.33Å
176L78Confident73.9Confident73 Ų7361.4 Ų61.438%0.38233%0.327SS..EExtended strand (participates in β ladder)trans-141152.5-174.9-71.8156.9000111.5D101 F190D101-L176 HydrophobicContact CB-CD1 3.67Å; D101-L176 HydrophobicContact CB-CG 4.41Å; D101-L176 WeakPolarHBondContact OD2-CD1 3.5Å; L176-F190 HydrophobicContact CB-CB 4.13Å; L176-F190 HydrophobicContact CB-CD2 3.98Å; L176-F190 PolarHBondContact N-O 3.12Å; L176-F190 PolarHBondContact O-N 2.92Å
177G66.9Low73Confident26 Ų2662.6 Ų62.627%0.26832%0.324SS..  trans-156.3168.5168.700000112.1
178P58.4Low72.1Confident14 Ų1459.6 Ų59.69%0.09132%0.316CS..  trans-62.3138.7-178.325.1-33.5000111.8F152 N180 F188F152-P178 VanDerWaalsContact CD2-O 3.25Å; F152-P178 WeakPolarHBondContact CD2-O 3.28Å; F152-P178 HydrophobicContact CE2-CG 4.17Å; F152-P178 WeakPolarHBondContact CE2-O 3.12Å; P178-N180 PolarHBondContact O-N 3.45Å; P178-F188 HydrophobicContact CB-CE1 4.31Å; P178-F188 HydrophobicContact CB-CZ 4.14Å; P178-F188 WeakPolarHBondContact CD-O 3.32Å; P178-F188 HydrophobicContact CG-CE1 4.38Å; P178-F188 HydrophobicContact CG-CZ 4.41Å
179A56.2Low71.3Confident67 Ų6757.7 Ų57.755%0.55432%0.319SS*.SBendtrans-55.3-32.2-177.900000113.6A151A151-A179 PolarHBondContact N-O 3.08Å
180N58.6Low70.8Confident52 Ų5262 Ų6228%0.27834%0.338SS..  trans-121.886.1178.5-79.40.4000112.2R149 P178 S182 E183R149-N180 PolarHBondContact O-OD1 3.08Å; P178-N180 PolarHBondContact O-N 3.45Å; N180-S182 PolarHBondContact O-N 2.93Å; N180-E183 PolarHBondContact ND2-OE2 2.94Å
181C58.1Low70.6Confident17 Ų1765 Ų6512%0.11535%0.35CS..THydrogen-bonded Turntrans-63-24.4177-58.20000115A151 F152A151-C181 HydrophobicContact CB-CB 4.25Å; F152-C181 WeakPolarHBondContact CE2-SG 3.18Å; F152-C181 WeakPolarHBondContact CZ-SG 3.28Å
182S55.2Low70.5Confident69 Ų6964.8 Ų64.848%0.48335%0.349SS..THydrogen-bonded Turntrans-83.4-11.2-171.453.30000114.7N180N180-S182 PolarHBondContact O-N 2.93Å
183E53.2Low70.4Confident151 Ų15171.2 Ų71.271%0.70637%0.373SS*.SBendtrans-107.6-8.9-175.2-70.6-177.4157.300114N180N180-E183 PolarHBondContact ND2-OE2 2.94Å
184E51Low70.2Confident79 Ų7971.2 Ų71.237%0.36937%0.373SS..  trans-87.1134.3177.6-67.9-169.5164.200111.3E186 F188E184-E186 PolarHBondContact O-N 3.02Å; E184-F188 WeakPolarHBondContact OE2-CD1 3.48Å; E184-F188 VanDerWaalsContact OE2-CE1 3.27Å; E184-F188 WeakPolarHBondContact OE2-CE1 3.38Å
185E54.1Low70Confident204 Ų20471.3 Ų71.395%0.95337%0.374SS*.SBendtrans-62.9-28.6174-73.2-173.2158.300112.1
186E57.9Low70.2Confident172 Ų17275.1 Ų75.180%0.80439%0.393SS*.SBendtrans-134.987.1174.5-69.3-17216600110.3E184E184-E186 PolarHBondContact O-N 3.02Å
187P64.8Low70.8Confident81 Ų8172.7 Ų72.753%0.52638%0.379SS..  trans-67.5136.4179.327.2-33.5000111
188F69.2Low71.8Confident102 Ų10273.1 Ų73.145%0.44737%0.374SS..  trans-115164.7177.962.8-87000112P178 E184 F190P178-F188 HydrophobicContact CB-CE1 4.31Å; P178-F188 HydrophobicContact CB-CZ 4.14Å; P178-F188 WeakPolarHBondContact CD-O 3.32Å; P178-F188 HydrophobicContact CG-CE1 4.38Å; P178-F188 HydrophobicContact CG-CZ 4.41Å; E184-F188 WeakPolarHBondContact OE2-CD1 3.48Å; E184-F188 VanDerWaalsContact OE2-CE1 3.27Å; E184-F188 WeakPolarHBondContact OE2-CE1 3.38Å; F188-F190 HydrophobicContact CD2-CD2 4.3Å; F188-F190 AromaticContact CD2-CE2 3.78Å; F188-F190 HydrophobicContact CD2-CE2 3.78Å; F188-F190 HydrophobicContact CD2-CZ 4.01Å; F188-F190 HydrophobicContact CE2-CD2 4.2Å; F188-F190 AromaticContact CE2-CE2 3.43Å; F188-F190 HydrophobicContact CE2-CE2 3.43Å; F188-F190 VanDerWaalsContact CE2-CE2 3.43Å; F188-F190 AromaticContact CE2-CZ 3.86Å; F188-F190 HydrophobicContact CE2-CZ 3.86Å
189G76.8Confident73.1Confident36 Ų3678.6 Ų78.637%0.37140%0.398SS..  trans-149.1138.6173.100000110.5
190F82.8Confident74.6Confident123 Ų12378.2 Ų78.254%0.53938%0.383SS..EExtended strand (participates in β ladder)trans-95.5119.4178-61.4-77.5000110S175 L176 F188S175-F190 PolarHBondContact N-O 3.33Å; L176-F190 HydrophobicContact CB-CB 4.13Å; L176-F190 HydrophobicContact CB-CD2 3.98Å; L176-F190 PolarHBondContact N-O 3.12Å; L176-F190 PolarHBondContact O-N 2.92Å; F188-F190 HydrophobicContact CD2-CD2 4.3Å; F188-F190 AromaticContact CD2-CE2 3.78Å; F188-F190 HydrophobicContact CD2-CE2 3.78Å; F188-F190 HydrophobicContact CD2-CZ 4.01Å; F188-F190 HydrophobicContact CE2-CD2 4.2Å; F188-F190 AromaticContact CE2-CE2 3.43Å; F188-F190 HydrophobicContact CE2-CE2 3.43Å; F188-F190 VanDerWaalsContact CE2-CE2 3.43Å; F188-F190 AromaticContact CE2-CZ 3.86Å; F188-F190 HydrophobicContact CE2-CZ 3.86Å
191Y88.6Confident76.2Confident64 Ų6475.8 Ų75.825%0.25137%0.37SS..EExtended strand (participates in β ladder)trans-110.4137.4176.5-70-100.6000110.4A140 L160 V173 L174 R193A140-Y191 WeakPolarHBondContact CB-OH 3.21Å; L160-Y191 HydrophobicContact CB-CD1 3.51Å; L160-Y191 HydrophobicContact CB-CE1 3.59Å; L160-Y191 HydrophobicContact CB-CG 4.01Å; L160-Y191 HydrophobicContact CD2-CD2 4.49Å; L160-Y191 HydrophobicContact CD2-CG 4.4Å; V173-Y191 CarbonylContact O-C 3.56Å; V173-Y191 WeakPolarHBondContact O-CA 3.48Å; L174-Y191 HydrophobicContact CB-CD1 4.04Å; L174-Y191 HydrophobicContact CB-CE1 3.64Å; L174-Y191 HydrophobicContact CD1-CD1 4.48Å; L174-Y191 HydrophobicContact CD1-CD2 4.41Å; L174-Y191 HydrophobicContact CD1-CE1 4.02Å; L174-Y191 HydrophobicContact CD1-CE2 3.92Å; L174-Y191 HydrophobicContact CG-CE1 4.39Å; L174-Y191 VanDerWaalsContact N-CD1 3.34Å; Y191-R193 PolarHBondContact O-N 3.07Å
192V90.4Very high77.7Confident14 Ų1477.9 Ų77.99%0.08538%0.379CS..EExtended strand (participates in β ladder)trans-65.1120.5167.9-178.80000108.4D104 I105 G172 V173 M194 Y197D104-V192 HydrophobicContact CB-CG2 3.94Å; D104-V192 WeakPolarHBondContact O-CG2 3.28Å; I105-V192 HydrophobicContact CB-CG1 4.43Å; G172-V192 CarbonylContact C-O 3.57Å; G172-V192 WeakPolarHBondContact CA-O 3.4Å; V173-V192 HydrophobicContact CB-CB 4.16Å; V173-V192 PolarHBondContact N-O 3.2Å; V173-V192 VanDerWaalsContact N-O 3.12Å; V173-V192 PolarHBondContact O-N 2.82Å; V192-M194 PolarHBondContact O-N 3.43Å; V192-M194 VanDerWaalsContact O-N 3.13Å; V192-Y197 HydrophobicContact CG1-CD2 3.82Å; V192-Y197 HydrophobicContact CG1-CE2 3.24Å
193R88.5Confident79.1Confident136 Ų13678 Ų7851%0.51338%0.375SS..EExtended strand (participates in β ladder)trans-66.7106.9178.4-92.1-172.154.8-170.4-3.7112.3Y191 D195 N196 Y197Y191-R193 PolarHBondContact O-N 3.07Å; R193-D195 VanDerWaalsContact C-N 3.33Å; R193-D195 IonicContact CZ-OD1 3.64Å; R193-D195 IonicContact CZ-OD2 3.65Å; R193-D195 IonicContact NE-OD1 2.75Å; R193-D195 PolarHBondContact NE-OD1 3.06Å; R193-D195 IonicContact NE-OD2 2.73Å; R193-D195 VanDerWaalsContact NH2-CG 3.33Å; R193-D195 IonicContact NH2-OD1 3.7Å; R193-D195 PolarHBondContact NH2-OD1 2.97Å; R193-D195 VanDerWaalsContact NH2-OD1 3.17Å; R193-D195 IonicContact NH2-OD2 3.15Å; R193-D195 PolarHBondContact NH2-OD2 3.11Å; R193-D195 PolarHBondContact O-N 3.17Å; R193-N196 PolarHBondContact NH2-OD1 3.35Å; R193-N196 PolarHBondContact O-N 3.41Å; R193-Y197 WeakPolarHBondContact O-CD2 3.25Å
194M90.4Very high80.7Confident0 Ų071.5 Ų71.50%035%0.345CS..G310 helixtrans-66.4-28.9-173.1-77.3-69.6-73.800114.5F35 I49 I105 L125 P126 A170 L171 V173 V192 N196 Y197 H198 I201F35-M194 HydrophobicContact CE2-CE 4.06Å; F35-M194 HydrophobicContact CZ-CE 3.93Å; F35-M194 HydrophobicContact CZ-SD 4.34Å; I49-M194 HydrophobicContact CD1-CE 3.7Å; I49-M194 HydrophobicContact CG2-CE 4.42Å; I105-M194 HydrophobicContact CD1-CE 4.5Å; I105-M194 HydrophobicContact CD1-SD 3.59Å; I105-M194 VanDerWaalsContact CD1-SD 3.59Å; L125-M194 HydrophobicContact CD2-CE 3.8Å; P126-M194 HydrophobicContact CG-CB 3.51Å; A170-M194 VanDerWaalsContact O-CB 3.3Å; A170-M194 WeakPolarHBondContact O-CB 3.37Å; A170-M194 WeakPolarHBondContact O-CG 3.32Å; L171-M194 WeakPolarHBondContact O-CB 3.38Å; L171-M194 PolarHBondContact O-N 3.41Å; V173-M194 HydrophobicContact CG2-CG 4.09Å; V173-M194 HydrophobicContact CG2-SD 3.44Å; V173-M194 WeakPolarHBondContact CG2-SD 3.37Å; V192-M194 PolarHBondContact O-N 3.43Å; V192-M194 VanDerWaalsContact O-N 3.13Å; M194-N196 PolarHBondContact O-N 3.43Å; M194-Y197 PolarHBondContact O-N 2.98Å; M194-Y197 VanDerWaalsContact O-N 3.07Å; M194-H198 PolarHBondContact O-N 3.16Å; M194-I201 HydrophobicContact CE-CD1 3.48Å; M194-I201 VanDerWaalsContact CE-CD1 3.48Å; M194-I201 HydrophobicContact SD-CD1 4.14Å
195D86.6Confident82.5Confident6 Ų668.9 Ų68.93%0.03233%0.334CS..G310 helixtrans-67.4-23.8-179.566.7-37.8000113.5P126 T131 R193 Y197P126-D195 HydrophobicContact CG-CB 4.47Å; T131-D195 WeakPolarHBondContact CB-OD2 3.48Å; T131-D195 HydrophobicContact CG2-CB 3.79Å; T131-D195 WeakPolarHBondContact OG1-CB 3.32Å; T131-D195 VanDerWaalsContact OG1-CG 3.3Å; T131-D195 PolarHBondContact OG1-OD2 3.07Å; R193-D195 VanDerWaalsContact C-N 3.33Å; R193-D195 IonicContact CZ-OD1 3.64Å; R193-D195 IonicContact CZ-OD2 3.65Å; R193-D195 IonicContact NE-OD1 2.75Å; R193-D195 PolarHBondContact NE-OD1 3.06Å; R193-D195 IonicContact NE-OD2 2.73Å; R193-D195 VanDerWaalsContact NH2-CG 3.33Å; R193-D195 IonicContact NH2-OD1 3.7Å; R193-D195 PolarHBondContact NH2-OD1 2.97Å; R193-D195 VanDerWaalsContact NH2-OD1 3.17Å; R193-D195 IonicContact NH2-OD2 3.15Å; R193-D195 PolarHBondContact NH2-OD2 3.11Å; R193-D195 PolarHBondContact O-N 3.17Å; D195-Y197 VanDerWaalsContact C-N 3.31Å
196N88.2Confident83.8Confident91 Ų9166.4 Ų66.449%0.48732%0.32SS..G310 helixtrans-72.8-25.6173-70.8-21.2000112.6R193 M194R193-N196 PolarHBondContact NH2-OD1 3.35Å; R193-N196 PolarHBondContact O-N 3.41Å; M194-N196 PolarHBondContact O-N 3.43Å
197Y90.9Very high84.8Confident22 Ų2263.5 Ų63.59%0.08631%0.306CS..SBendtrans-1002.8-178.1-61.2-88.6000112.8H94 N103 I105 V192 R193 M194 D195 E199 W200 I201H94-Y197 AromaticContact CD2-CD1 3.94Å; H94-Y197 AromaticContact CD2-CE1 3.92Å; N103-Y197 WeakPolarHBondContact CA-OH 3.37Å; N103-Y197 HydrophobicContact CB-CE1 4.39Å; N103-Y197 PolarHBondContact OD1-OH 3.29Å; I105-Y197 HydrophobicContact CD1-CG 4.32Å; I105-Y197 HydrophobicContact CG2-CD1 3.79Å; I105-Y197 HydrophobicContact CG2-CE1 3.79Å; I105-Y197 HydrophobicContact CG2-CG 4.22Å; V192-Y197 HydrophobicContact CG1-CD2 3.82Å; V192-Y197 HydrophobicContact CG1-CE2 3.24Å; R193-Y197 WeakPolarHBondContact O-CD2 3.25Å; M194-Y197 PolarHBondContact O-N 2.98Å; M194-Y197 VanDerWaalsContact O-N 3.07Å; D195-Y197 VanDerWaalsContact C-N 3.31Å; Y197-E199 PolarHBondContact O-N 3.03Å; Y197-W200 HydrophobicContact CD1-CE3 4.21Å; Y197-W200 PolarHBondContact O-N 3.31Å; Y197-W200 VanDerWaalsContact O-N 3.08Å; Y197-I201 WeakPolarHBondContact O-CB 3.49Å; Y197-I201 WeakPolarHBondContact O-CG1 3.17Å; Y197-I201 PolarHBondContact O-N 3.05Å
198H88.3Confident85.4Confident36 Ų3659.7 Ų59.717%0.16728%0.281CS..Hα-helixtrans-48.9-53.5-175.3-172.886.8000113.2P126 M194 I201 L202P126-H198 PolarHBondContact O-ND1 2.68Å; M194-H198 PolarHBondContact O-N 3.16Å; H198-I201 PolarHBondContact O-N 2.99Å; H198-L202 WeakPolarHBondContact NE2-CD1 3.23Å; H198-L202 WeakPolarHBondContact O-CG 3.26Å; H198-L202 PolarHBondContact O-N 3.24Å; H198-L202 VanDerWaalsContact O-N 3.12Å
199E84.8Confident85.3Confident129 Ų12960.3 Ų60.360%0.60329%0.285SS*.Hα-helixtrans-66-42.6179.6-64-59.7151.800112Y197 I201 L202 D203Y197-E199 PolarHBondContact O-N 3.03Å; E199-I201 VanDerWaalsContact C-N 3.32Å; E199-I201 PolarHBondContact O-N 3Å; E199-L202 PolarHBondContact O-N 3.1Å; E199-D203 PolarHBondContact O-N 3.22Å
200W89.3Confident84.3Confident58 Ų5863.7 Ų63.722%0.2230%0.299CS..Hα-helixtrans-61.7-41.1177.8173.980.9000111.8H94 I105 L107 Y197 D203 T204H94-W200 HydrophobicContact CB-CH2 3.99Å; H94-W200 HydrophobicContact CB-CZ2 3.8Å; H94-W200 AromaticContact CD2-CD1 3.66Å; H94-W200 AromaticContact CD2-CD2 3.61Å; H94-W200 AromaticContact CD2-CE2 3.51Å; H94-W200 AromaticContact CD2-CG 3.73Å; H94-W200 AromaticContact CD2-NE1 3.53Å; I105-W200 HydrophobicContact CD1-CZ3 4.12Å; I105-W200 HydrophobicContact CG1-CZ3 4.11Å; I105-W200 HydrophobicContact CG2-CH2 4.27Å; I105-W200 HydrophobicContact CG2-CZ3 3.87Å; L107-W200 HydrophobicContact CD1-CE3 4.38Å; L107-W200 HydrophobicContact CD1-CH2 3.68Å; L107-W200 HydrophobicContact CD1-CZ3 3.41Å; L107-W200 VanDerWaalsContact CD1-CZ3 3.41Å; Y197-W200 HydrophobicContact CD1-CE3 4.21Å; Y197-W200 PolarHBondContact O-N 3.31Å; Y197-W200 VanDerWaalsContact O-N 3.08Å; W200-D203 PolarHBondContact O-N 2.93Å; W200-T204 VanDerWaalsContact CE2-OG1 3.28Å; W200-T204 HydrophobicContact CZ2-CG2 4.32Å; W200-T204 PolarHBondContact NE1-OG1 3.18Å; W200-T204 WeakPolarHBondContact O-CB 3.48Å; W200-T204 PolarHBondContact O-N 2.9Å; W200-T204 PolarHBondContact O-OG1 2.9Å
201I91.5Very high82.4Confident1 Ų160 Ų601%0.00529%0.286CS..Hα-helixtrans-60.4-52.7176.5-69.3165.5000109.1I49 I105 L107 L125 M194 Y197 H198 E199 D203 T204 M205I49-I201 HydrophobicContact CD1-CD1 4.06Å; I49-I201 HydrophobicContact CD1-CG1 4.37Å; I49-I201 HydrophobicContact CD1-CG2 4.14Å; I105-I201 HydrophobicContact CD1-CD1 4.24Å; I105-I201 HydrophobicContact CD1-CG1 4.5Å; L107-I201 HydrophobicContact CD1-CG1 4.33Å; L107-I201 HydrophobicContact CD2-CG2 4.34Å; L125-I201 HydrophobicContact CD1-CG2 3.64Å; L125-I201 HydrophobicContact CD2-CD1 4.17Å; L125-I201 HydrophobicContact CD2-CG2 4.22Å; M194-I201 HydrophobicContact CE-CD1 3.48Å; M194-I201 VanDerWaalsContact CE-CD1 3.48Å; M194-I201 HydrophobicContact SD-CD1 4.14Å; Y197-I201 WeakPolarHBondContact O-CB 3.49Å; Y197-I201 WeakPolarHBondContact O-CG1 3.17Å; Y197-I201 PolarHBondContact O-N 3.05Å; H198-I201 PolarHBondContact O-N 2.99Å; E199-I201 VanDerWaalsContact C-N 3.32Å; E199-I201 PolarHBondContact O-N 3Å; I201-D203 VanDerWaalsContact C-N 3.34Å; I201-D203 PolarHBondContact O-N 3.05Å; I201-T204 PolarHBondContact O-N 2.85Å; I201-M205 HydrophobicContact CG2-CG 4.34Å; I201-M205 HydrophobicContact CG2-SD 3.54Å; I201-M205 VanDerWaalsContact CG2-SD 3.54Å; I201-M205 WeakPolarHBondContact O-CB 3.3Å; I201-M205 WeakPolarHBondContact O-CG 3.49Å; I201-M205 PolarHBondContact O-N 3.01Å
202L89.1Confident80.1Confident61 Ų6161.8 Ų61.832%0.31931%0.306SS..Hα-helixtrans-61.3-39.8-178.4-68.6-179.5000113L125 H198 E199 K206L125-L202 HydrophobicContact CD1-CD2 4.3Å; H198-L202 WeakPolarHBondContact NE2-CD1 3.23Å; H198-L202 WeakPolarHBondContact O-CG 3.26Å; H198-L202 PolarHBondContact O-N 3.24Å; H198-L202 VanDerWaalsContact O-N 3.12Å; E199-L202 PolarHBondContact O-N 3.1Å; L202-K206 WeakPolarHBondContact O-CE 3.19Å; L202-K206 WeakPolarHBondContact O-CG 3.33Å; L202-K206 PolarHBondContact O-N 3.25Å
203D84.8Confident77.4Confident72 Ų7267.3 Ų67.339%0.38534%0.335SS..Hα-helixtrans-74.7-39.1178.7-78.7-13.2000112.5E199 W200 I201 M205 K206 Q207E199-D203 PolarHBondContact O-N 3.22Å; W200-D203 PolarHBondContact O-N 2.93Å; I201-D203 VanDerWaalsContact C-N 3.34Å; I201-D203 PolarHBondContact O-N 3.05Å; D203-M205 VanDerWaalsContact C-N 3.34Å; D203-M205 PolarHBondContact O-N 3.45Å; D203-K206 PolarHBondContact O-N 3.48Å; D203-K206 IonicContact OD1-NZ 2.75Å; D203-K206 PolarHBondContact OD1-NZ 2.9Å; D203-Q207 WeakPolarHBondContact O-CG 3.31Å; D203-Q207 PolarHBondContact O-N 2.81Å
204T86.9Confident74.5Confident15 Ų1570.5 Ų70.59%0.09235%0.347CS..Hα-helixtrans-64.5-40.3175.5-600000110.8A92 L107 W200 I201 K206 Q207 I208A92-T204 HydrophobicContact CB-CG2 3.41Å; A92-T204 VanDerWaalsContact CB-CG2 3.41Å; L107-T204 HydrophobicContact CB-CG2 4.47Å; L107-T204 HydrophobicContact CD2-CG2 3.82Å; W200-T204 VanDerWaalsContact CE2-OG1 3.28Å; W200-T204 HydrophobicContact CZ2-CG2 4.32Å; W200-T204 PolarHBondContact NE1-OG1 3.18Å; W200-T204 WeakPolarHBondContact O-CB 3.48Å; W200-T204 PolarHBondContact O-N 2.9Å; W200-T204 PolarHBondContact O-OG1 2.9Å; I201-T204 PolarHBondContact O-N 2.85Å; T204-K206 PolarHBondContact O-N 3.02Å; T204-Q207 CarbonylContact O-C 3.55Å; T204-Q207 PolarHBondContact O-N 2.88Å; T204-I208 VanDerWaalsContact O-CB 3.3Å; T204-I208 WeakPolarHBondContact O-CB 3.45Å; T204-I208 PolarHBondContact O-N 3.34Å
205M88.3Confident71.8Confident24 Ų2473.5 Ų73.512%0.11837%0.368CS..Hα-helixtrans-59.2-33176.2-72.8168.281.300113.1V37 D38 N39 I47 L107 I201 D203V37-M205 HydrophobicContact CG2-CE 4.15Å; D38-M205 WeakPolarHBondContact O-CE 3.47Å; N39-M205 HydrophobicContact CB-CE 3.38Å; I47-M205 HydrophobicContact CB-CE 4.02Å; I47-M205 HydrophobicContact CG1-CE 3.8Å; I47-M205 HydrophobicContact CG1-CG 4.21Å; I47-M205 HydrophobicContact CG2-CE 4.1Å; I47-M205 HydrophobicContact CG2-CG 4.08Å; I47-M205 HydrophobicContact CG2-SD 4.44Å; L107-M205 HydrophobicContact CD2-CG 3.68Å; I201-M205 HydrophobicContact CG2-CG 4.34Å; I201-M205 HydrophobicContact CG2-SD 3.54Å; I201-M205 VanDerWaalsContact CG2-SD 3.54Å; I201-M205 WeakPolarHBondContact O-CB 3.3Å; I201-M205 WeakPolarHBondContact O-CG 3.49Å; I201-M205 PolarHBondContact O-N 3.01Å; D203-M205 VanDerWaalsContact C-N 3.34Å; D203-M205 PolarHBondContact O-N 3.45Å
206K81.7Confident68.9Low152 Ų15279.7 Ų79.766%0.66140%0.401SS*.Hα-helixtrans-73.3-29.4174.6-63.6165.8-161.5155.30112.5L202 D203 T204L202-K206 WeakPolarHBondContact O-CE 3.19Å; L202-K206 WeakPolarHBondContact O-CG 3.33Å; L202-K206 PolarHBondContact O-N 3.25Å; D203-K206 PolarHBondContact O-N 3.48Å; D203-K206 IonicContact OD1-NZ 2.75Å; D203-K206 PolarHBondContact OD1-NZ 2.9Å; T204-K206 PolarHBondContact O-N 3.02Å
207Q78.8Confident66Low111 Ų11183.8 Ų83.852%0.51942%0.417SS..Hα-helixtrans-107.4-16.9-168.7-65-177.72000114.7D203 T204 E209 T210 V211D203-Q207 WeakPolarHBondContact O-CG 3.31Å; D203-Q207 PolarHBondContact O-N 2.81Å; T204-Q207 CarbonylContact O-C 3.55Å; T204-Q207 PolarHBondContact O-N 2.88Å; Q207-E209 PolarHBondContact O-N 2.93Å; Q207-T210 WeakPolarHBondContact O-CA 3.49Å; Q207-T210 PolarHBondContact O-N 2.71Å; Q207-T210 PolarHBondContact O-OG1 3.11Å; Q207-V211 PolarHBondContact O-N 2.83Å
208I78.4Confident63Low0 Ų089.1 Ų89.10%045%0.447CS..THydrogen-bonded Turntrans-56.8-23-172-165.7163.2000113.8I47 N90 A92 L107 K109 T204 T210I47-I208 HydrophobicContact CD1-CG2 4.25Å; N90-I208 PolarHBondContact ND2-O 2.77Å; A92-I208 HydrophobicContact CB-CD1 3.99Å; A92-I208 HydrophobicContact CB-CG1 4.09Å; L107-I208 HydrophobicContact CB-CD1 3.87Å; L107-I208 WeakPolarHBondContact O-CD1 3.06Å; K109-I208 HydrophobicContact CB-CD1 4.01Å; K109-I208 HydrophobicContact CB-CG1 4.15Å; K109-I208 HydrophobicContact CB-CG2 4.25Å; K109-I208 HydrophobicContact CD-CG2 3.97Å; K109-I208 HydrophobicContact CG-CG2 4.31Å; T204-I208 VanDerWaalsContact O-CB 3.3Å; T204-I208 WeakPolarHBondContact O-CB 3.45Å; T204-I208 PolarHBondContact O-N 3.34Å; I208-T210 VanDerWaalsContact C-N 3.33Å
209E66.6Low60.3Low116 Ų11690 Ų9054%0.54246%0.455SS..THydrogen-bonded Turntrans-73-25.1173-60.9-147.7125.100114K89 Q207K89-E209 IonicContact NZ-OE1 3.21Å; K89-E209 PolarHBondContact NZ-OE1 2.95Å; Q207-E209 PolarHBondContact O-N 2.93Å
210T54.7Low57.7Low106 Ų10689.7 Ų89.765%0.6546%0.462SS*.THydrogen-bonded Turntrans-105.8-8.4-174.859.90000113.9Q207 I208 P212Q207-T210 WeakPolarHBondContact O-CA 3.49Å; Q207-T210 PolarHBondContact O-N 2.71Å; Q207-T210 PolarHBondContact O-OG1 3.11Å; I208-T210 VanDerWaalsContact C-N 3.33Å; T210-P212 WeakPolarHBondContact O-CD 3.19Å
211V44.6Very low55Low46 Ų4690.7 Ų90.728%0.27948%0.483SS..  trans-62.7109.3176-179.10000107.9N90 Q207N90-V211 PolarHBondContact ND2-O 2.9Å; Q207-V211 PolarHBondContact O-N 2.83Å
212P39.9Very low52.2Low101 Ų10194.9 Ų94.966%0.65650%0.504SS*.  trans-65.6145.8173.4-10.527.8000108.1T210 R214T210-P212 WeakPolarHBondContact O-CD 3.19Å; P212-R214 PolarHBondContact O-N 3.37Å
213D32.5Very low49.2Very low130 Ų13097.1 Ų97.170%0.69551%0.514SS*.  trans-45.3117.7167.2-163.77.6000108.1S215D213-S215 PolarHBondContact O-N 3.28Å; D213-S215 PolarHBondContact OD1-OG 2.83Å; D213-S215 PolarHBondContact OD2-OG 2.82Å
214R28.7Very low46.8Very low203 Ų20397 Ų9777%0.76652%0.523SS*.SBendtrans-75.627.9-177.5-90.1-170.3177.2-178.22.7111.7P212P212-R214 PolarHBondContact O-N 3.37Å
215S33.4Very low44.2Very low64 Ų6499.9 Ų99.945%0.44854%0.544SS..  trans-91.496.6161.353.80000107.4D213D213-S215 PolarHBondContact O-N 3.28Å; D213-S215 PolarHBondContact OD1-OG 2.83Å; D213-S215 PolarHBondContact OD2-OG 2.82Å
216D26Very low41.5Very low135 Ų135102.2 Ų102.272%0.72256%0.559SS**  trans144.250.3159.2-74.5-21.5000114.6
217H26.5Very low39.2Very low178 Ų17899.5 Ų99.582%0.82456%0.556SS**SBendtrans-114.585.9163.3-77.7-10.7000110.8
218N29.1Very low37Very low133 Ų133105.1 Ų105.171%0.71157%0.572SS**SBendtrans155.26.6138.9-81.9-21.9000116T220N218-T220 PolarHBondContact O-N 2.95Å
219V30.4Very low34.7Very low56 Ų56116.1 Ų116.134%0.33961%0.614SS.*Hα-helixtrans-74.4-25-179.5-175.30000113.1A221 I222 M223V219-A221 VanDerWaalsContact C-N 3.31Å; V219-A221 PolarHBondContact O-N 2.94Å; V219-I222 PolarHBondContact O-N 3.29Å; V219-M223 HydrophobicContact CG1-CG 3.86Å; V219-M223 PolarHBondContact O-N 2.89Å
220T30.7Very low33.1Very low122 Ų122117.4 Ų117.475%0.74862%0.623SS**Hα-helixtrans-65-30.8-174.7-23.50000113.6N218 A224N218-T220 PolarHBondContact O-N 2.95Å; T220-A224 PolarHBondContact O-N 3.09Å
221A33.2Very low31.8Very low79 Ų79116.4 Ų116.465%0.65363%0.626SS**Hα-helixtrans-76.9-33.3178.700000112.3V219V219-A221 VanDerWaalsContact C-N 3.31Å; V219-A221 PolarHBondContact O-N 2.94Å
222I31.3Very low31Very low88 Ų88120.3 Ų120.345%0.45165%0.65SS.*Hα-helixtrans-76.9-42.4-180-58177.2000109.8V219 A224 S225 V226V219-I222 PolarHBondContact O-N 3.29Å; I222-A224 VanDerWaalsContact C-N 3.29Å; I222-A224 PolarHBondContact O-N 3.11Å; I222-S225 WeakPolarHBondContact O-CB 3.1Å; I222-S225 PolarHBondContact O-N 2.72Å; I222-S225 PolarHBondContact O-OG 2.92Å; I222-V226 PolarHBondContact O-N 2.88Å
223M27.1Very low30.6Very low108 Ų108124.9 Ų124.953%0.53266%0.66SS.*Hα-helixtrans-60.6-33.9177.3-84.2-69.1-164.700113.5V219 S225 V226 T227V219-M223 HydrophobicContact CG1-CG 3.86Å; V219-M223 PolarHBondContact O-N 2.89Å; M223-S225 PolarHBondContact O-N 3.12Å; M223-V226 PolarHBondContact O-N 3.44Å; M223-T227 WeakPolarHBondContact O-CB 3.49Å; M223-T227 PolarHBondContact O-N 3.05Å; M223-T227 PolarHBondContact O-OG1 2.59Å
224A33.2Very low30.6Very low70 Ų70124.6 Ų124.658%0.57967%0.665SS**Hα-helixtrans-62.4-29.717500000112.6T220 I222T220-A224 PolarHBondContact O-N 3.09Å; I222-A224 VanDerWaalsContact C-N 3.29Å; I222-A224 PolarHBondContact O-N 3.11Å
225S33.9Very low30.9Very low76 Ų76121.6 Ų121.653%0.53166%0.664SS.*Hα-helixtrans-79.2-35.9176.5800000112.6I222 M223I222-S225 WeakPolarHBondContact O-CB 3.1Å; I222-S225 PolarHBondContact O-N 2.72Å; I222-S225 PolarHBondContact O-OG 2.92Å; M223-S225 PolarHBondContact O-N 3.12Å
226V31.6Very low30.9Very low72 Ų72124.3 Ų124.344%0.43668%0.678SS.*Hα-helixtrans-74.2-39.1-179.4-179.90000111.3I222 M223 R228 R229I222-V226 PolarHBondContact O-N 2.88Å; M223-V226 PolarHBondContact O-N 3.44Å; V226-R228 PolarHBondContact O-N 2.67Å; V226-R228 VanDerWaalsContact O-N 3.16Å; V226-R229 PolarHBondContact O-N 3.01Å
227T33.2Very low31.4Very low96 Ų96124.1 Ų124.159%0.58968%0.684SS**Hα-helixtrans-64-25.4-176.7-47.90000112.4M223 R229M223-T227 WeakPolarHBondContact O-CB 3.49Å; M223-T227 PolarHBondContact O-N 3.05Å; M223-T227 PolarHBondContact O-OG1 2.59Å; T227-R229 VanDerWaalsContact C-N 3.3Å; T227-R229 PolarHBondContact O-N 2.68Å
228R32.7Very low32.4Very low229 Ų229123.9 Ų123.986%0.86468%0.681SS**THydrogen-bonded Turntrans-71.5-19.8176.7-120.8-178.1-156.9172.87.4114V226V226-R228 PolarHBondContact O-N 2.67Å; V226-R228 VanDerWaalsContact O-N 3.16Å
229R30.5Very low34.1Very low230 Ų230120.1 Ų120.187%0.86867%0.665SS**THydrogen-bonded Turntrans-89.5-13.3-178-74.5-172.2178.6-1741.2114.5V226 T227V226-R229 PolarHBondContact O-N 3.01Å; T227-R229 VanDerWaalsContact C-N 3.3Å; T227-R229 PolarHBondContact O-N 2.68Å
230L31.8Very low36.1Very low143 Ų143122.2 Ų122.275%0.74968%0.68SS**SBendtrans-110.87.2-175.6-69.6169.9000114.8T232L230-T232 PolarHBondContact O-N 3.32Å
231A27.8Very low38.4Very low85 Ų85118.8 Ų118.870%0.70265%0.653SS**  trans-78.264174.800000112.5
232T28.5Very low40.8Very low128 Ų128121 Ų12179%0.78565%0.654SS**  trans-139.1122.3158.757.50000112.3L230L230-T232 PolarHBondContact O-N 3.32Å
233K30.1Very low43.3Very low197 Ų197118.5 Ų118.586%0.85764%0.643SS**  trans81.5121.5175.4-70.9-174.8176.71780118.9
234P33.1Very low46.1Very low124 Ų124115.2 Ų115.281%0.80563%0.627SS**  trans-86.4116176.833.6-28.3000110.1
235N34.4Very low48.5Very low141 Ų141113.8 Ų113.875%0.75461%0.611SS**  trans-130.2130.6162.4-84.3-28.3000107.5
236T33.9Very low50.8Low121 Ų121112.2 Ų112.274%0.74260%0.598SS**  trans-42.6139.4169.943.50000111K238T236-K238 PolarHBondContact O-N 2.82Å
237P35.5Very low53Low130 Ų130110.2 Ų110.284%0.84459%0.589SS**  trans-56.9115.9-177-15.124.6000109.8
238K48.8Very low54.8Low174 Ų174109.2 Ų109.276%0.75758%0.578SS**  trans-65.7134.9172.2-74.4-176.8174.9-176.80108T236T236-K238 PolarHBondContact O-N 2.82Å
239S63.4Low56.7Low53 Ų53101.1 Ų101.137%0.37155%0.551SS.*  trans-48.7140168.3170.60000109.6Y241 Q305S239-Y241 PolarHBondContact O-N 3.5Å; S239-Y241 PolarHBondContact OG-N 2.87Å; S239-Y241 PolarHBondContact OG-O 2.81Å; S239-Q305 PolarHBondContact O-NE2 3.34Å
240P73.8Confident58.4Low101 Ų10197.2 Ų97.266%0.65655%0.547SS*.SBendtrans-70-6.2176.830.2-34.6000112.9F570P240-F570 HydrophobicContact CB-CE2 4.21Å
241Y79.4Confident60.2Low50 Ų5091.9 Ų91.920%0.19652%0.522CS..  trans-108134.4179.5-50.5-83.5000111.8S239 M244 Q305 F570 H572S239-Y241 PolarHBondContact O-N 3.5Å; S239-Y241 PolarHBondContact OG-N 2.87Å; S239-Y241 PolarHBondContact OG-O 2.81Å; Y241-M244 HydrophobicContact CD1-SD 3.93Å; Y241-M244 HydrophobicContact CD2-CB 4.49Å; Y241-M244 HydrophobicContact CD2-SD 4.13Å; Y241-M244 HydrophobicContact CE1-SD 3.9Å; Y241-M244 HydrophobicContact CE2-SD 4.12Å; Y241-M244 HydrophobicContact CG-CB 4.31Å; Y241-M244 HydrophobicContact CG-SD 4.06Å; Y241-Q305 PolarHBondContact O-NE2 2.92Å; Y241-F570 HydrophobicContact CD1-CZ 4.24Å; Y241-F570 AromaticContact CE1-CE1 3.87Å; Y241-F570 HydrophobicContact CE1-CE1 3.87Å; Y241-F570 AromaticContact CE1-CZ 3.44Å; Y241-F570 HydrophobicContact CE1-CZ 3.44Å; Y241-F570 VanDerWaalsContact CE1-CZ 3.44Å; Y241-F570 AromaticContact CZ-CZ 3.77Å; Y241-H572 AromaticContact CE1-ND1 3.6Å; Y241-H572 AromaticContact CZ-ND1 3.46Å; Y241-H572 PolarHBondContact OH-CE1 3.41Å; Y241-H572 PolarHBondContact OH-ND1 3.26Å
242D83.4Confident62.6Low126 Ų12689.6 Ų89.667%0.67450%0.503SS*.SBendtrans-73.6-34.9162-67.3-30.1000111.1Q305 Y306D242-Q305 CarbonylContact O-C 3.48Å; D242-Q305 VanDerWaalsContact O-CA 3.3Å; D242-Q305 WeakPolarHBondContact O-CA 3.49Å; D242-Y306 PolarHBondContact O-N 2.9Å
243T83.6Confident65.4Low34 Ų3483.5 Ų83.521%0.20947%0.466CS..EExtended strand (participates in β ladder)trans-139.9128.9176.6-62.40000110.9V245 P298 Y306 M591T243-V245 HydrophobicContact CG2-CG2 4.08Å; T243-P298 HydrophobicContact CG2-CG 4.12Å; T243-P298 WeakPolarHBondContact OG1-CG 3.39Å; T243-Y306 CarbonylContact C-O 3.46Å; T243-Y306 VanDerWaalsContact CA-O 3.27Å; T243-Y306 WeakPolarHBondContact CA-O 3.4Å; T243-Y306 HydrophobicContact CG2-CD1 4.17Å; T243-M591 HydrophobicContact CG2-CE 3.89Å; T243-M591 HydrophobicContact CG2-SD 4.43Å
244M86Confident68.3Low40 Ų4076.3 Ų76.320%0.19744%0.435CS..EExtended strand (participates in β ladder)trans-132.5112.8172.2-171.178.7-153.600109.7Y241 T246 Y306 S307 S308 H572Y241-M244 HydrophobicContact CD1-SD 3.93Å; Y241-M244 HydrophobicContact CD2-CB 4.49Å; Y241-M244 HydrophobicContact CD2-SD 4.13Å; Y241-M244 HydrophobicContact CE1-SD 3.9Å; Y241-M244 HydrophobicContact CE2-SD 4.12Å; Y241-M244 HydrophobicContact CG-CB 4.31Å; Y241-M244 HydrophobicContact CG-SD 4.06Å; M244-T246 HydrophobicContact CE-CG2 3.84Å; M244-T246 HydrophobicContact CG-CG2 4.47Å; M244-Y306 PolarHBondContact N-O 3.36Å; M244-S307 WeakPolarHBondContact O-CA 3.35Å; M244-S307 PolarHBondContact O-OG 3.29Å; M244-S308 PolarHBondContact O-N 2.84Å; M244-S308 VanDerWaalsContact O-N 3.09Å; M244-H572 WeakPolarHBondContact CE-CE1 3.48Å
245V83.1Confident71.2Confident39 Ų3970.5 Ų70.524%0.23640%0.397CS..EExtended strand (participates in β ladder)trans-117.3117.8175.1-176.70000109.6T243 V297 Y306 S308 F312T243-V245 HydrophobicContact CG2-CG2 4.08Å; V245-V297 HydrophobicContact CG2-CG1 4.24Å; V245-Y306 HydrophobicContact CG2-CD1 4.23Å; V245-Y306 HydrophobicContact CG2-CE1 3.94Å; V245-S308 CarbonylContact C-O 3.54Å; V245-S308 WeakPolarHBondContact CA-O 3.3Å; V245-F312 HydrophobicContact CG1-CE1 3.7Å; V245-F312 HydrophobicContact CG1-CZ 4.14Å
246T82.4Confident74.2Confident43 Ų4364 Ų6426%0.26436%0.362SS..EExtended strand (participates in β ladder)trans-106.5129.9177.255.70000110.1M244 S308 S309 G310M244-T246 HydrophobicContact CE-CG2 3.84Å; M244-T246 HydrophobicContact CG-CG2 4.47Å; T246-S308 PolarHBondContact N-O 3.09Å; T246-S309 CarbonylContact O-C 3.46Å; T246-S309 VanDerWaalsContact O-CA 3.3Å; T246-S309 WeakPolarHBondContact O-CA 3.37Å; T246-S309 WeakPolarHBondContact OG1-CA 3.23Å; T246-S309 VanDerWaalsContact OG1-CB 3.23Å; T246-S309 WeakPolarHBondContact OG1-CB 3.39Å; T246-G310 PolarHBondContact O-N 2.69Å
247A78.2Confident77.2Confident31 Ų3159.5 Ų59.526%0.25633%0.333SS..  trans-132132.8177.800000111.4G310 F312A247-G310 VanDerWaalsContact CA-O 3.24Å; A247-G310 WeakPolarHBondContact CA-O 3.41Å; A247-G310 VanDerWaalsContact CB-O 3.29Å; A247-G310 WeakPolarHBondContact CB-O 3.32Å; A247-F312 HydrophobicContact CB-CD1 3.83Å; A247-F312 HydrophobicContact CB-CD2 3.48Å; A247-F312 VanDerWaalsContact CB-CD2 3.48Å; A247-F312 HydrophobicContact CB-CE1 3.67Å; A247-F312 HydrophobicContact CB-CE2 3.32Å; A247-F312 HydrophobicContact CB-CG 3.74Å; A247-F312 HydrophobicContact CB-CZ 3.42Å; A247-F312 VanDerWaalsContact CB-CZ 3.42Å
248H70.9Confident80.1Confident75 Ų7553.9 Ų53.935%0.34730%0.295SS..  trans-87.1126.2171.2-60.1-70.2000109.1
249L72.3Confident82.4Confident59 Ų5946.4 Ų46.431%0.30926%0.263SS..  trans-87.7150.6172.9-59.2178.2000109.9S251 A253 V283 L595L249-S251 WeakPolarHBondContact CB-O 3.34Å; L249-S251 PolarHBondContact O-N 2.67Å; L249-A253 HydrophobicContact CD1-CB 3.84Å; L249-V283 HydrophobicContact CD1-CG1 3.77Å; L249-V283 HydrophobicContact CD2-CG1 4.31Å; L249-L595 HydrophobicContact CD1-CD1 3.5Å
250N66.5Low83.8Confident147 Ų14746 Ų4679%0.78626%0.259SS*.SBendtrans-69.6-24.8178.1-68.1-19.4000112.7
251S69.5Low84.2Confident32 Ų3246.8 Ų46.822%0.22425%0.254CS..SBendtrans-139153.1174.8-172.60000108.3L249 D287L249-S251 WeakPolarHBondContact CB-O 3.34Å; L249-S251 PolarHBondContact O-N 2.67Å; S251-D287 WeakPolarHBondContact CB-OD2 3.36Å; S251-D287 PolarHBondContact OG-N 3.3Å
252A78.6Confident83.7Confident36 Ų3647.7 Ų47.730%0.29826%0.262SS..  trans-62.4154.6170.900000110S285 L286A252-S285 WeakPolarHBondContact O-CA 3.25Å; A252-L286 HydrophobicContact CB-CD1 3.61Å; A252-L286 HydrophobicContact CB-CG 4.3Å; A252-L286 WeakPolarHBondContact O-CB 3.38Å; A252-L286 PolarHBondContact O-N 3.28Å
253A86.8Confident82.4Confident0 Ų052.1 Ų52.10%027%0.269CS..EExtended strand (participates in β ladder)trans-141.5152-172.200000111.2L249 V283 G284 S580 L595L249-A253 HydrophobicContact CD1-CB 3.84Å; A253-V283 HydrophobicContact CB-CG1 3.76Å; A253-G284 WeakPolarHBondContact CA-O 3.3Å; A253-G284 WeakPolarHBondContact CB-O 3.43Å; A253-S580 PolarHBondContact O-OG 3.29Å; A253-L595 HydrophobicContact CB-CD1 4.06Å; A253-L595 HydrophobicContact CB-CD2 3.65Å; A253-L595 HydrophobicContact CB-CG 4.31Å; A253-L595 WeakPolarHBondContact O-CD2 3.41Å; A253-L595 WeakPolarHBondContact O-CG 2.99Å
254F90Very high80.8Confident47 Ų4760.8 Ų60.821%0.20630%0.3CS..EExtended strand (participates in β ladder)trans-110-15.1-179.2-81.1-53.5000113.6G284 L286 D581 I597F254-G284 PolarHBondContact N-O 2.77Å; F254-L286 HydrophobicContact CD2-CD2 3.37Å; F254-L286 HydrophobicContact CD2-CG 4.32Å; F254-L286 HydrophobicContact CE2-CD2 3.06Å; F254-L286 HydrophobicContact CE2-CG 4.25Å; F254-L286 HydrophobicContact CG-CD2 4.38Å; F254-L286 HydrophobicContact CZ-CD2 3.84Å; F254-D581 WeakPolarHBondContact O-CB 3.39Å; F254-I597 HydrophobicContact CD1-CD1 3.84Å; F254-I597 HydrophobicContact CE1-CB 4.47Å; F254-I597 HydrophobicContact CE1-CD1 3.09Å; F254-I597 HydrophobicContact CE1-CG1 4.34Å; F254-I597 HydrophobicContact CE1-CG2 4.4Å; F254-I597 HydrophobicContact CE2-CD1 4.19Å; F254-I597 HydrophobicContact CZ-CD1 3.28Å
255S95.3Very high79.1Confident1 Ų163.3 Ų63.31%0.00732%0.322CS..EExtended strand (participates in β ladder)trans-133.4129-172.8-165.70000111.4V283 G284 A327 R328 D581S255-V283 CarbonylContact O-C 3.58Å; S255-V283 VanDerWaalsContact O-CA 3.31Å; S255-V283 WeakPolarHBondContact O-CA 3.33Å; S255-G284 PolarHBondContact N-O 2.88Å; S255-G284 PolarHBondContact O-N 3.49Å; S255-A327 PolarHBondContact OG-N 3.42Å; S255-A327 PolarHBondContact OG-O 3.5Å; S255-R328 PolarHBondContact OG-NH1 3.24Å; S255-D581 WeakPolarHBondContact CA-OD2 3.41Å
256V96.8Very high77.1Confident5 Ų565 Ų653%0.0334%0.335CS..EExtended strand (participates in β ladder)trans-132.6138.6173.269.20000110.4L281 L282 V283 R328 D581 A593 L595V256-L281 HydrophobicContact CG2-CD2 3.81Å; V256-L282 CarbonylContact C-O 3.59Å; V256-L282 VanDerWaalsContact CA-O 3.29Å; V256-L282 WeakPolarHBondContact CA-O 3.22Å; V256-V283 HydrophobicContact CG2-CG2 4.5Å; V256-R328 PolarHBondContact O-NH1 3.01Å; V256-D581 HydrophobicContact CG1-CB 4.01Å; V256-D581 PolarHBondContact N-OD2 2.79Å; V256-D581 VanDerWaalsContact O-OD2 3.1Å; V256-A593 HydrophobicContact CG2-CB 4.07Å; V256-L595 HydrophobicContact CB-CB 4.34Å; V256-L595 HydrophobicContact CB-CD2 4.31Å; V256-L595 HydrophobicContact CG1-CB 4.05Å
257Q97.6Very high75.2Confident27 Ų2768.9 Ų68.913%0.12636%0.364CS..EExtended strand (participates in β ladder)trans-149.5130.1171.7-160.3-176.725.600112.1L281 L282 R328 Y329 S583Q257-L281 WeakPolarHBondContact O-CA 3.24Å; Q257-L282 HydrophobicContact CB-CB 4.39Å; Q257-L282 PolarHBondContact N-O 3.1Å; Q257-L282 PolarHBondContact O-N 2.87Å; Q257-R328 VanDerWaalsContact CD-CD 3.48Å; Q257-R328 VanDerWaalsContact OE1-CA 3.25Å; Q257-Y329 HydrophobicContact CG-CD1 4.13Å; Q257-Y329 HydrophobicContact CG-CE1 3.94Å; Q257-S583 WeakPolarHBondContact CA-OG 3.3Å
258W96.9Very high73.4Confident12 Ų1271 Ų715%0.04538%0.377CS..EExtended strand (participates in β ladder)trans-67.3132.3168-73.6104.6000111.3R279 L281 V297 Y329 S583 W584 D585 M591 A593W258-R279 HydrophobicContact CE3-CB 3.9Å; W258-R279 HydrophobicContact CH2-CB 4.23Å; W258-R279 HydrophobicContact CZ3-CB 3.35Å; W258-R279 HydrophobicContact CZ3-CG 4.4Å; W258-L281 HydrophobicContact CB-CD2 4.48Å; W258-L281 HydrophobicContact CD2-CD2 3.37Å; W258-L281 HydrophobicContact CD2-CG 4.04Å; W258-L281 HydrophobicContact CE3-CD1 4.48Å; W258-L281 HydrophobicContact CE3-CD2 3.53Å; W258-L281 HydrophobicContact CE3-CG 3.66Å; W258-L281 HydrophobicContact CG-CD2 3.79Å; W258-L281 HydrophobicContact CH2-CD1 3.84Å; W258-L281 HydrophobicContact CH2-CD2 4.13Å; W258-L281 HydrophobicContact CH2-CG 3.93Å; W258-L281 HydrophobicContact CZ2-CD1 4.19Å; W258-L281 HydrophobicContact CZ2-CD2 4.01Å; W258-L281 HydrophobicContact CZ2-CG 4.29Å; W258-L281 HydrophobicContact CZ3-CD1 3.98Å; W258-L281 HydrophobicContact CZ3-CD2 3.88Å; W258-L281 HydrophobicContact CZ3-CG 3.57Å; W258-V297 HydrophobicContact CH2-CG1 4.44Å; W258-Y329 WeakPolarHBondContact O-CE1 3.38Å; W258-S583 PolarHBondContact N-OG 3.03Å; W258-S583 PolarHBondContact NE1-O 3.4Å; W258-W584 VanDerWaalsContact CD1-C 3.45Å; W258-D585 HydrophobicContact CB-CB 4.47Å; W258-D585 HydrophobicContact CD2-CB 4.18Å; W258-D585 HydrophobicContact CG-CB 3.95Å; W258-M591 HydrophobicContact CZ2-CG 4.1Å; W258-A593 HydrophobicContact CZ2-CB 4.02Å
259L95.7Very high71.9Confident17 Ų1778.6 Ų78.69%0.08940%0.402CS..PPolyproline II helixtrans-87.2147.3168.4-75.684.9000110.6R279 R280 L282 L292 Y329L259-R279 PolarHBondContact O-NH2 3.17Å; L259-R279 VanDerWaalsContact O-NH2 3.13Å; L259-R280 HydrophobicContact CB-CB 4.25Å; L259-R280 HydrophobicContact CD1-CB 4.34Å; L259-R280 PolarHBondContact N-O 2.78Å; L259-L282 HydrophobicContact CD1-CB 3.82Å; L259-L292 HydrophobicContact CD1-CD1 3.6Å; L259-L292 HydrophobicContact CD2-CD1 3.88Å; L259-L292 HydrophobicContact CG-CD1 4.41Å; L259-Y329 HydrophobicContact CG-CD1 4.47Å
260P92.6Very high70.5Confident44 Ų4479.2 Ų79.229%0.28641%0.412SS..PPolyproline II helixtrans-65.7160.4175.828.7-35.5000112.5N262 Y329 P334 D587P260-N262 PolarHBondContact O-N 3.5Å; P260-Y329 HydrophobicContact CG-CE2 4.26Å; P260-P334 HydrophobicContact CG-CB 3.68Å; P260-P334 HydrophobicContact CG-CG 3.38Å; P260-D587 WeakPolarHBondContact CA-OD2 3.38Å
261E82.5Confident69.2Low117 Ų11780.1 Ų80.155%0.54742%0.417SS..PPolyproline II helixtrans-64.4135.1-178.9-158.3173.4-179.600111.7R263 R279 D587E261-R263 PolarHBondContact O-N 2.8Å; E261-R263 VanDerWaalsContact O-N 3.07Å; E261-R279 VanDerWaalsContact N-NH1 3.13Å; E261-D587 PolarHBondContact N-OD2 3.25Å
262N68.5Low68Low70 Ų7081.6 Ų81.637%0.37443%0.427SS..  trans-77.799.6178.2-154.3-0.6000109.5P260 Y264 S265P260-N262 PolarHBondContact O-N 3.5Å; N262-Y264 PolarHBondContact O-N 3.09Å; N262-S265 PolarHBondContact O-N 2.84Å
263R57.2Low66.5Low218 Ų21884 Ų8482%0.82344%0.442SS*.G310 helixtrans-53.3-27.3-177.6-65.6-173.8-177.3-176.11.6113.3E261 S265 S266E261-R263 PolarHBondContact O-N 2.8Å; E261-R263 VanDerWaalsContact O-N 3.07Å; R263-S265 VanDerWaalsContact C-N 3.33Å; R263-S265 PolarHBondContact O-N 2.75Å; R263-S266 PolarHBondContact O-N 3.09Å; R263-S266 PolarHBondContact O-OG 3.43Å
264Y50.5Low65Low217 Ų21786 Ų8685%0.85146%0.463SS*.G310 helixtrans-74.4-13.3177.8-66.5-75.8000115N262 S266N262-Y264 PolarHBondContact O-N 3.09Å; Y264-S266 PolarHBondContact O-N 3.37Å
265S48.3Very low64.4Low93 Ų9391.8 Ų91.865%0.6548%0.483SS*.G310 helixtrans-80.6-0.4173.3-171.70000113N262 R263 S267N262-S265 PolarHBondContact O-N 2.84Å; R263-S265 VanDerWaalsContact C-N 3.33Å; R263-S265 PolarHBondContact O-N 2.75Å; S265-S267 VanDerWaalsContact C-N 3.28Å; S265-S267 PolarHBondContact O-N 2.92Å; S265-S267 VanDerWaalsContact O-N 3.16Å
266S42.6Very low63.8Low74 Ų7494.7 Ų94.752%0.51750%0.498SS..  trans-87.848.5-177.8690000113.5R263 Y264 S268R263-S266 PolarHBondContact O-N 3.09Å; R263-S266 PolarHBondContact O-OG 3.43Å; Y264-S266 PolarHBondContact O-N 3.37Å; S266-S268 PolarHBondContact O-N 2.79Å
267S41.6Very low63.4Low125 Ų12596.5 Ų96.587%0.87451%0.509SS*.SBendtrans-78.59.8163.453.10000113.4S265S265-S267 VanDerWaalsContact C-N 3.28Å; S265-S267 PolarHBondContact O-N 2.92Å; S265-S267 VanDerWaalsContact O-N 3.16Å
268S41.1Very low63Low75 Ų75101.4 Ų101.452%0.52453%0.527SS..  trans-134.284.9165.477.10000112S266 S270S266-S268 PolarHBondContact O-N 2.79Å; S268-S270 PolarHBondContact O-N 3.07Å
269R39.7Very low62.8Low234 Ų234101.2 Ų101.288%0.88353%0.526SS*.  trans-70.936.7161.8-82.7-175.1170.3178.8-2.8112.5N271R269-N271 PolarHBondContact O-N 3.02Å
270S42.1Very low62.8Low73 Ų73103.6 Ų103.651%0.5153%0.533SS..  trans-77.5115.5168.769.60000108.2S268 S272S268-S270 PolarHBondContact O-N 3.07Å; S270-S272 PolarHBondContact O-N 2.94Å
271N39.9Very low63Low165 Ų165101.7 Ų101.788%0.88252%0.521SS*.  trans-61.945.5169.4-87.2-14000112.8R269 S273R269-N271 PolarHBondContact O-N 3.02Å; N271-S273 PolarHBondContact O-N 2.81Å
272S43.6Very low63.6Low64 Ų6496.2 Ų96.245%0.44850%0.495SS..  trans-75.895.1170.959.50000108.2S270S270-S272 PolarHBondContact O-N 2.94Å
273S47.2Very low65Low87 Ų8793 Ų9361%0.60848%0.479SS*.THydrogen-bonded Turntrans-44.5136.1158.6168.40000109.6N271N271-S273 PolarHBondContact O-N 2.81Å
274G55.5Low66.7Low42 Ų4282.7 Ų82.743%0.43344%0.439SS..THydrogen-bonded Turntrans88.526.617100000118.9N301 Y302G274-N301 PolarHBondContact N-O 3.13Å; G274-Y302 WeakPolarHBondContact O-CE2 3.29Å
275R76.9Confident68.5Low167 Ų16772.4 Ų72.463%0.6340%0.4SS*.  trans-104.6141174.9-160177.1-177.7173.13.1113.6G299R275-G299 PolarHBondContact O-N 2.94Å
276L83.7Confident70.1Confident62 Ų6270 Ų7033%0.32538%0.379SS..EExtended strand (participates in β ladder)trans-66.5129.1165.2-60.3175.2000110.6V297 P298 Y302 Y306L276-V297 CarbonylContact C-O 3.28Å; L276-V297 WeakPolarHBondContact CA-O 3.42Å; L276-P298 HydrophobicContact CD2-CG 4.02Å; L276-Y302 HydrophobicContact CD2-CE2 4.18Å; L276-Y306 HydrophobicContact CD1-CD2 4.42Å; L276-Y306 HydrophobicContact CD1-CE2 3.58Å; L276-Y306 HydrophobicContact CD2-CD1 4.42Å; L276-Y306 HydrophobicContact CD2-CD2 3.66Å; L276-Y306 HydrophobicContact CD2-CE1 4.28Å; L276-Y306 HydrophobicContact CD2-CE2 3.53Å; L276-Y306 HydrophobicContact CD2-CG 4.11Å; L276-Y306 HydrophobicContact CG-CE2 4.19Å
277V88.6Confident71.8Confident44 Ų4470.3 Ų70.327%0.26738%0.375SS..EExtended strand (participates in β ladder)trans-103.1161.8175.6-62.20000110.8R279 K296 V297 I588V277-R279 HydrophobicContact CG2-CG 4.13Å; V277-K296 WeakPolarHBondContact O-CA 3.43Å; V277-V297 HydrophobicContact CG2-CG2 3.97Å; V277-V297 WeakPolarHBondContact CG2-O 3.19Å; V277-V297 PolarHBondContact N-O 2.93Å; V277-V297 PolarHBondContact O-N 2.87Å; V277-I588 HydrophobicContact CG2-CD1 4.06Å
278R89.3Confident73.8Confident130 Ų13064.4 Ų64.449%0.49133%0.333SS..EExtended strand (participates in β ladder)trans-100.6121.7173.8-70.3179.9179.6101.16.2109.2E294 A295 K296 R359R278-E294 HydrophobicContact CB-CG 4.11Å; R278-E294 HydrophobicContact CG-CG 4.29Å; R278-E294 IonicContact NE-OE1 3.91Å; R278-A295 WeakPolarHBondContact CA-O 3.09Å; R278-K296 HydrophobicContact CG-CG 4.43Å; R278-R359 VanDerWaalsContact NH2-NH2 3.12Å
279R92.3Very high76.1Confident7 Ų761.5 Ų61.53%0.02631%0.313CS..EExtended strand (participates in β ladder)trans-116150.4176-62.7-66.1-65.2163.60.9109.2W258 L259 E261 V277 E294 A295 V297 D585 D587 I588W258-R279 HydrophobicContact CE3-CB 3.9Å; W258-R279 HydrophobicContact CH2-CB 4.23Å; W258-R279 HydrophobicContact CZ3-CB 3.35Å; W258-R279 HydrophobicContact CZ3-CG 4.4Å; L259-R279 PolarHBondContact O-NH2 3.17Å; L259-R279 VanDerWaalsContact O-NH2 3.13Å; E261-R279 VanDerWaalsContact N-NH1 3.13Å; V277-R279 HydrophobicContact CG2-CG 4.13Å; R279-E294 WeakPolarHBondContact O-CA 3.48Å; R279-A295 PolarHBondContact N-O 2.93Å; R279-A295 PolarHBondContact O-N 3.24Å; R279-V297 HydrophobicContact CB-CG2 3.99Å; R279-V297 HydrophobicContact CG-CG2 3.33Å; R279-D585 IonicContact CZ-OD1 3.84Å; R279-D585 IonicContact CZ-OD2 2.83Å; R279-D585 IonicContact NE-OD1 3.92Å; R279-D585 IonicContact NE-OD2 3.77Å; R279-D585 PolarHBondContact NE-OD2 2.85Å; R279-D585 IonicContact NH2-OD1 3.73Å; R279-D585 PolarHBondContact NH2-OD1 3.27Å; R279-D585 IonicContact NH2-OD2 3.65Å; R279-D585 PolarHBondContact NH2-OD2 2.98Å; R279-D587 IonicContact CZ-OD2 3.82Å; R279-D587 IonicContact NH1-OD2 2.82Å; R279-D587 PolarHBondContact NH1-OD2 2.04Å; R279-D587 IonicContact NH2-OD2 2.81Å; R279-D587 PolarHBondContact NH2-OD2 3.13Å; R279-I588 HydrophobicContact CG-CD1 3.83Å
280R95Very high78.8Confident67 Ų6750.5 Ų50.525%0.25327%0.272SS..EExtended strand (participates in β ladder)trans-114.4139.5-175.5-68.4178.8-176.9171.90.1111.1L259 L292 C293L259-R280 HydrophobicContact CB-CB 4.25Å; L259-R280 HydrophobicContact CD1-CB 4.34Å; L259-R280 PolarHBondContact N-O 2.78Å; R280-L292 HydrophobicContact CB-CD1 4.16Å; R280-C293 CarbonylContact C-O 3.53Å; R280-C293 WeakPolarHBondContact CA-O 3.42Å
281L95.9Very high81.3Confident4 Ų448 Ų482%0.02125%0.252CS..EExtended strand (participates in β ladder)trans-119.7133.4177.9-76.5164.9000109.6V256 Q257 W258 V283 L292 C293 F312 A593V256-L281 HydrophobicContact CG2-CD2 3.81Å; Q257-L281 WeakPolarHBondContact O-CA 3.24Å; W258-L281 HydrophobicContact CB-CD2 4.48Å; W258-L281 HydrophobicContact CD2-CD2 3.37Å; W258-L281 HydrophobicContact CD2-CG 4.04Å; W258-L281 HydrophobicContact CE3-CD1 4.48Å; W258-L281 HydrophobicContact CE3-CD2 3.53Å; W258-L281 HydrophobicContact CE3-CG 3.66Å; W258-L281 HydrophobicContact CG-CD2 3.79Å; W258-L281 HydrophobicContact CH2-CD1 3.84Å; W258-L281 HydrophobicContact CH2-CD2 4.13Å; W258-L281 HydrophobicContact CH2-CG 3.93Å; W258-L281 HydrophobicContact CZ2-CD1 4.19Å; W258-L281 HydrophobicContact CZ2-CD2 4.01Å; W258-L281 HydrophobicContact CZ2-CG 4.29Å; W258-L281 HydrophobicContact CZ3-CD1 3.98Å; W258-L281 HydrophobicContact CZ3-CD2 3.88Å; W258-L281 HydrophobicContact CZ3-CG 3.57Å; L281-V283 HydrophobicContact CB-CG2 4.22Å; L281-L292 CarbonylContact O-C 3.51Å; L281-L292 WeakPolarHBondContact O-CA 3.33Å; L281-C293 HydrophobicContact CB-CB 4.27Å; L281-C293 PolarHBondContact N-O 2.92Å; L281-C293 PolarHBondContact O-N 2.93Å; L281-F312 HydrophobicContact CD1-CD2 4.33Å; L281-F312 HydrophobicContact CD1-CE2 3.74Å; L281-F312 HydrophobicContact CD1-CZ 4.12Å; L281-A593 HydrophobicContact CD2-CB 3.87Å
282L97.1Very high83.9Confident2 Ų240.3 Ų40.31%0.0121%0.211CC..EExtended strand (participates in β ladder)trans-88.3124.5165.7-168.165.4000108.2V256 Q257 L259 L290 A327 V337 L351V256-L282 CarbonylContact C-O 3.59Å; V256-L282 VanDerWaalsContact CA-O 3.29Å; V256-L282 WeakPolarHBondContact CA-O 3.22Å; Q257-L282 HydrophobicContact CB-CB 4.39Å; Q257-L282 PolarHBondContact N-O 3.1Å; Q257-L282 PolarHBondContact O-N 2.87Å; L259-L282 HydrophobicContact CD1-CB 3.82Å; L282-L290 HydrophobicContact CD1-CD1 3.82Å; L282-L290 HydrophobicContact CD1-CD2 3.97Å; L282-L290 HydrophobicContact CD1-CG 3.85Å; L282-L290 HydrophobicContact CD2-CD1 4.47Å; L282-L290 HydrophobicContact CG-CD1 3.89Å; L282-L290 HydrophobicContact CG-CG 4.48Å; L282-A327 HydrophobicContact CD2-CB 3.86Å; L282-A327 HydrophobicContact CG-CB 4.37Å; L282-V337 HydrophobicContact CD2-CG1 3.68Å; L282-V337 HydrophobicContact CD2-CG2 4.22Å; L282-L351 HydrophobicContact CD1-CD1 4.12Å
283V96.3Very high86.3Confident4 Ų437.5 Ų37.52%0.02419%0.191CC..EExtended strand (participates in β ladder)trans-128.3113.7-177-176.20000110.2L249 A253 S255 V256 L281 L290 N291L249-V283 HydrophobicContact CD1-CG1 3.77Å; L249-V283 HydrophobicContact CD2-CG1 4.31Å; A253-V283 HydrophobicContact CB-CG1 3.76Å; S255-V283 CarbonylContact O-C 3.58Å; S255-V283 VanDerWaalsContact O-CA 3.31Å; S255-V283 WeakPolarHBondContact O-CA 3.33Å; V256-V283 HydrophobicContact CG2-CG2 4.5Å; L281-V283 HydrophobicContact CB-CG2 4.22Å; V283-L290 WeakPolarHBondContact O-CA 3.28Å; V283-N291 HydrophobicContact CB-CB 4.49Å; V283-N291 PolarHBondContact N-O 3.35Å; V283-N291 PolarHBondContact O-N 2.83Å
284G94.3Very high88.4Confident0 Ų034.7 Ų34.70%017%0.169CC..EExtended strand (participates in β ladder)trans-96.4115.3177.600000111.4A253 F254 S255A253-G284 WeakPolarHBondContact CA-O 3.3Å; A253-G284 WeakPolarHBondContact CB-O 3.43Å; F254-G284 PolarHBondContact N-O 2.77Å; S255-G284 PolarHBondContact N-O 2.88Å; S255-G284 PolarHBondContact O-N 3.49Å
285S88Confident90.1Very high2 Ų232.9 Ų32.91%0.01415%0.149CC..EExtended strand (participates in β ladder)trans-104.2156.6-167.3-44.80000113.1A252 D287 G288 V289 N291 I324A252-S285 WeakPolarHBondContact O-CA 3.25Å; S285-D287 VanDerWaalsContact C-N 3.28Å; S285-D287 WeakPolarHBondContact CB-OD1 3.43Å; S285-D287 PolarHBondContact O-N 2.94Å; S285-G288 PolarHBondContact O-N 2.95Å; S285-G288 VanDerWaalsContact O-N 3.07Å; S285-V289 VanDerWaalsContact CB-O 3.25Å; S285-V289 WeakPolarHBondContact CB-O 3.3Å; S285-V289 PolarHBondContact N-O 3.36Å; S285-V289 VanDerWaalsContact N-O 3.12Å; S285-V289 PolarHBondContact OG-O 2.99Å; S285-N291 PolarHBondContact OG-ND2 2.96Å; S285-I324 PolarHBondContact O-N 2.84Å
286L81Confident90.6Very high43 Ų4330 Ų3023%0.22514%0.141CC..THydrogen-bonded Turntrans-64.5-27.8175.3-74.6-178.6000113.1A252 F254 G288 E323 I597A252-L286 HydrophobicContact CB-CD1 3.61Å; A252-L286 HydrophobicContact CB-CG 4.3Å; A252-L286 WeakPolarHBondContact O-CB 3.38Å; A252-L286 PolarHBondContact O-N 3.28Å; F254-L286 HydrophobicContact CD2-CD2 3.37Å; F254-L286 HydrophobicContact CD2-CG 4.32Å; F254-L286 HydrophobicContact CE2-CD2 3.06Å; F254-L286 HydrophobicContact CE2-CG 4.25Å; F254-L286 HydrophobicContact CG-CD2 4.38Å; F254-L286 HydrophobicContact CZ-CD2 3.84Å; L286-G288 PolarHBondContact O-N 3.31Å; L286-E323 HydrophobicContact CD2-CB 4.36Å; L286-E323 HydrophobicContact CD2-CG 4.47Å; L286-E323 VanDerWaalsContact O-CG 3.28Å; L286-E323 WeakPolarHBondContact O-CG 3.21Å; L286-I597 HydrophobicContact CD1-CD1 3.89Å; L286-I597 HydrophobicContact CD1-CG1 4.49Å
287D78.3Confident90.9Very high80 Ų8027.2 Ų27.243%0.42813%0.127SC..THydrogen-bonded Turntrans-71.74.3173.365.5-2000113S251 S285 V289S251-D287 WeakPolarHBondContact CB-OD2 3.36Å; S251-D287 PolarHBondContact OG-N 3.3Å; S285-D287 VanDerWaalsContact C-N 3.28Å; S285-D287 WeakPolarHBondContact CB-OD1 3.43Å; S285-D287 PolarHBondContact O-N 2.94Å; D287-V289 VanDerWaalsContact C-N 3.32Å; D287-V289 WeakPolarHBondContact OD1-CB 3.32Å; D287-V289 PolarHBondContact OD1-N 3.43Å
288G84.7Confident90.8Very high0 Ų025.4 Ų25.40%012%0.116CC..SBendtrans75.218.8-178.200000113.9S285 L286 S319 A320 S322S285-G288 PolarHBondContact O-N 2.95Å; S285-G288 VanDerWaalsContact O-N 3.07Å; L286-G288 PolarHBondContact O-N 3.31Å; G288-S319 CarbonylContact O-C 3.46Å; G288-S319 WeakPolarHBondContact O-CA 3.46Å; G288-A320 PolarHBondContact O-N 2.61Å; G288-S322 WeakPolarHBondContact CA-O 3.29Å
289V89Confident90.5Very high15 Ų1519.9 Ų19.99%0.09110%0.1CC..EExtended strand (participates in β ladder)trans-104.5122.5177.1-1730000111.4S285 D287 A317 V365S285-V289 VanDerWaalsContact CB-O 3.25Å; S285-V289 WeakPolarHBondContact CB-O 3.3Å; S285-V289 PolarHBondContact N-O 3.36Å; S285-V289 VanDerWaalsContact N-O 3.12Å; S285-V289 PolarHBondContact OG-O 2.99Å; D287-V289 VanDerWaalsContact C-N 3.32Å; D287-V289 WeakPolarHBondContact OD1-CB 3.32Å; D287-V289 PolarHBondContact OD1-N 3.43Å; V289-A317 HydrophobicContact CG1-CB 4.09Å; V289-V365 HydrophobicContact CG1-CG1 3.88Å; V289-V365 HydrophobicContact CG1-CG2 4.35Å; V289-V365 HydrophobicContact CG2-CG1 4.07Å
290L95.6Very high89.8Confident3 Ų328.6 Ų28.62%0.01613%0.133CC..EExtended strand (participates in β ladder)trans-86.9112.7169-171.669.3000109.2L282 V283 A317 V318 I324 A327 V337 M339 F349L282-L290 HydrophobicContact CD1-CD1 3.82Å; L282-L290 HydrophobicContact CD1-CD2 3.97Å; L282-L290 HydrophobicContact CD1-CG 3.85Å; L282-L290 HydrophobicContact CD2-CD1 4.47Å; L282-L290 HydrophobicContact CG-CD1 3.89Å; L282-L290 HydrophobicContact CG-CG 4.48Å; V283-L290 WeakPolarHBondContact O-CA 3.28Å; L290-A317 WeakPolarHBondContact O-CA 3.23Å; L290-V318 PolarHBondContact N-O 3.11Å; L290-V318 PolarHBondContact O-N 3.3Å; L290-I324 HydrophobicContact CB-CD1 3.74Å; L290-I324 HydrophobicContact CD1-CD1 4.45Å; L290-A327 HydrophobicContact CD1-CB 3.49Å; L290-A327 VanDerWaalsContact CD1-CB 3.49Å; L290-V337 HydrophobicContact CD2-CG1 4.03Å; L290-M339 HydrophobicContact CB-SD 4.07Å; L290-M339 HydrophobicContact CD2-SD 4.19Å; L290-F349 HydrophobicContact CD2-CE2 4.12Å; L290-F349 HydrophobicContact CD2-CZ 3.56Å
291N94.7Very high89Confident20 Ų2030.5 Ų30.511%0.10715%0.148CC..EExtended strand (participates in β ladder)trans-103.1131.7179.4-66.8-64.9000110.5V283 S285V283-N291 HydrophobicContact CB-CB 4.49Å; V283-N291 PolarHBondContact N-O 3.35Å; V283-N291 PolarHBondContact O-N 2.83Å; S285-N291 PolarHBondContact OG-ND2 2.96Å
292L95.3Very high88.1Confident4 Ų432.7 Ų32.72%0.02116%0.156CC..EExtended strand (participates in β ladder)trans-94.3106.3162.2-177.167000107.6L259 R280 L281 V315 K316L259-L292 HydrophobicContact CD1-CD1 3.6Å; L259-L292 HydrophobicContact CD2-CD1 3.88Å; L259-L292 HydrophobicContact CG-CD1 4.41Å; R280-L292 HydrophobicContact CB-CD1 4.16Å; L281-L292 CarbonylContact O-C 3.51Å; L281-L292 WeakPolarHBondContact O-CA 3.33Å; L292-V315 HydrophobicContact CD2-CB 4.33Å; L292-V315 HydrophobicContact CD2-CG1 4.38Å; L292-V315 HydrophobicContact CG-CB 4.35Å; L292-V315 WeakPolarHBondContact O-CA 3.09Å; L292-V315 WeakPolarHBondContact O-CB 3.32Å; L292-V315 PolarHBondContact O-N 2.81Å; L292-K316 HydrophobicContact CB-CB 3.96Å; L292-K316 HydrophobicContact CD2-CB 4.43Å; L292-K316 HydrophobicContact CD2-CD 3.86Å; L292-K316 HydrophobicContact CD2-CG 4.16Å; L292-K316 PolarHBondContact N-O 3.06Å; L292-K316 PolarHBondContact O-N 3.14Å
293C93.8Very high87Confident4 Ų439.7 Ų39.73%0.02719%0.194CC..EExtended strand (participates in β ladder)trans-96.5148.4-177.6-680000111R280 L281 F312 R313R280-C293 CarbonylContact C-O 3.53Å; R280-C293 WeakPolarHBondContact CA-O 3.42Å; L281-C293 HydrophobicContact CB-CB 4.27Å; L281-C293 PolarHBondContact N-O 2.92Å; L281-C293 PolarHBondContact O-N 2.93Å; C293-F312 HydrophobicContact CB-CB 3.78Å; C293-F312 HydrophobicContact CB-CD2 4.25Å; C293-F312 HydrophobicContact CB-CG 4.34Å; C293-R313 CarbonylContact C-O 3.53Å; C293-R313 WeakPolarHBondContact CA-O 3.3Å
294E92.1Very high86.1Confident29 Ų2946 Ų4614%0.13622%0.223CC..EExtended strand (participates in β ladder)trans-118.8122.4173.7176.7177.790.600109.6R278 R279 R313 V315R278-E294 HydrophobicContact CB-CG 4.11Å; R278-E294 HydrophobicContact CG-CG 4.29Å; R278-E294 IonicContact NE-OE1 3.91Å; R279-E294 WeakPolarHBondContact O-CA 3.48Å; E294-R313 HydrophobicContact CB-CB 4.41Å; E294-R313 PolarHBondContact N-O 3.26Å; E294-R313 PolarHBondContact O-N 2.79Å; E294-R313 IonicContact OE1-CZ 3.62Å; E294-R313 IonicContact OE1-NH1 3.02Å; E294-R313 PolarHBondContact OE1-NH1 3.29Å; E294-V315 HydrophobicContact CB-CG2 3.47Å; E294-V315 VanDerWaalsContact CB-CG2 3.47Å
295A89.8Confident85.4Confident3 Ų350.5 Ų50.53%0.02524%0.244CC..EExtended strand (participates in β ladder)trans-110.6143.4177.900000110.3R278 R279 V297 F312R278-A295 WeakPolarHBondContact CA-O 3.09Å; R279-A295 PolarHBondContact N-O 2.93Å; R279-A295 PolarHBondContact O-N 3.24Å; A295-V297 HydrophobicContact CB-CG1 4.29Å; A295-F312 HydrophobicContact CB-CD1 3.72Å; A295-F312 HydrophobicContact CB-CE1 3.49Å; A295-F312 VanDerWaalsContact CB-CE1 3.49Å; A295-F312 HydrophobicContact CB-CZ 4.17Å
296K88.2Confident84.9Confident107 Ų10752.4 Ų52.447%0.46525%0.251SS..EExtended strand (participates in β ladder)trans-93.3119.4166.5-70.9-177.1-174.3172.50108.4V277 R278V277-K296 WeakPolarHBondContact O-CA 3.43Å; R278-K296 HydrophobicContact CG-CG 4.43Å
297V89.3Confident84.7Confident3 Ų354.5 Ų54.52%0.01827%0.269CS..EExtended strand (participates in β ladder)trans-132.5155.9179.5-60.20000109.9V245 W258 L276 V277 R279 A295 I588 M591V245-V297 HydrophobicContact CG2-CG1 4.24Å; W258-V297 HydrophobicContact CH2-CG1 4.44Å; L276-V297 CarbonylContact C-O 3.28Å; L276-V297 WeakPolarHBondContact CA-O 3.42Å; V277-V297 HydrophobicContact CG2-CG2 3.97Å; V277-V297 WeakPolarHBondContact CG2-O 3.19Å; V277-V297 PolarHBondContact N-O 2.93Å; V277-V297 PolarHBondContact O-N 2.87Å; R279-V297 HydrophobicContact CB-CG2 3.99Å; R279-V297 HydrophobicContact CG-CG2 3.33Å; A295-V297 HydrophobicContact CB-CG1 4.29Å; V297-I588 HydrophobicContact CG2-CD1 3.83Å; V297-M591 HydrophobicContact CB-CE 4.39Å
298P86.3Confident84.5Confident6 Ų652.8 Ų52.84%0.03926%0.264CS..EExtended strand (participates in β ladder)trans-52.2136.4167.2-33.243.7000112.7T243 L276 Y302 Y306T243-P298 HydrophobicContact CG2-CG 4.12Å; T243-P298 WeakPolarHBondContact OG1-CG 3.39Å; L276-P298 HydrophobicContact CD2-CG 4.02Å; P298-Y302 HydrophobicContact CB-CD1 3.6Å; P298-Y302 HydrophobicContact CB-CD2 4.2Å; P298-Y302 HydrophobicContact CB-CE1 4.29Å; P298-Y302 HydrophobicContact CB-CG 3.56Å; P298-Y302 HydrophobicContact CG-CD1 3.86Å; P298-Y302 HydrophobicContact CG-CE1 4.09Å; P298-Y302 HydrophobicContact CG-CG 4.23Å; P298-Y306 HydrophobicContact CG-CD1 3.79Å; P298-Y306 HydrophobicContact CG-CG 3.67Å
299G82.8Confident83.9Confident14 Ų1456 Ų5614%0.14429%0.286CS..  trans-77174.2170.100000112.2R275 N301 Y302R275-G299 PolarHBondContact O-N 2.94Å; G299-N301 PolarHBondContact O-N 3.07Å; G299-Y302 VanDerWaalsContact O-CB 3.23Å; G299-Y302 WeakPolarHBondContact O-CB 3.33Å; G299-Y302 PolarHBondContact O-N 2.98Å; G299-Y302 VanDerWaalsContact O-N 3.11Å
300R79.1Confident82.4Confident191 Ų19156.5 Ų56.572%0.72129%0.294SS*.THydrogen-bonded Turntrans-54.5-29.7-175.8-171.7175.8-179.6-175.71.5115.7
301N76.9Confident81.1Confident106 Ų10661.3 Ų61.357%0.56733%0.326SS*.THydrogen-bonded Turntrans-106.228-177-60.9-17.3000112.4G274 G299G274-N301 PolarHBondContact N-O 3.13Å; G299-N301 PolarHBondContact O-N 3.07Å
302Y77.3Confident80.5Confident50 Ų5062.6 Ų62.620%0.19633%0.33CS..  trans-93.6124.4177.5-164.3-87.9000109.2G274 L276 P298 G299 E304G274-Y302 WeakPolarHBondContact O-CE2 3.29Å; L276-Y302 HydrophobicContact CD2-CE2 4.18Å; P298-Y302 HydrophobicContact CB-CD1 3.6Å; P298-Y302 HydrophobicContact CB-CD2 4.2Å; P298-Y302 HydrophobicContact CB-CE1 4.29Å; P298-Y302 HydrophobicContact CB-CG 3.56Å; P298-Y302 HydrophobicContact CG-CD1 3.86Å; P298-Y302 HydrophobicContact CG-CE1 4.09Å; P298-Y302 HydrophobicContact CG-CG 4.23Å; G299-Y302 VanDerWaalsContact O-CB 3.23Å; G299-Y302 WeakPolarHBondContact O-CB 3.33Å; G299-Y302 PolarHBondContact O-N 2.98Å; G299-Y302 VanDerWaalsContact O-N 3.11Å; Y302-E304 HydrophobicContact CD1-CB 4.27Å; Y302-E304 WeakPolarHBondContact CD1-O 3.46Å; Y302-E304 HydrophobicContact CE1-CB 3.61Å; Y302-E304 WeakPolarHBondContact CE1-O 3.35Å
303N73.2Confident80Confident150 Ų15066.2 Ų66.280%0.80234%0.344SS*.  trans-111.87.8-170.2-64.9-11.5000113.4
304E77.9Confident79.8Confident137 Ų13767.5 Ų67.564%0.6435%0.35SS*.SBendtrans-108156.1179.3-61.6179.5175.700110.8Y302Y302-E304 HydrophobicContact CD1-CB 4.27Å; Y302-E304 WeakPolarHBondContact CD1-O 3.46Å; Y302-E304 HydrophobicContact CE1-CB 3.61Å; Y302-E304 WeakPolarHBondContact CE1-O 3.35Å
305Q79.3Confident79.9Confident94 Ų9466.3 Ų66.344%0.43935%0.345SS..  trans-70.1134.1170.5-69.5-172.7-23.800110S239 Y241 D242S239-Q305 PolarHBondContact O-NE2 3.34Å; Y241-Q305 PolarHBondContact O-NE2 2.92Å; D242-Q305 CarbonylContact O-C 3.48Å; D242-Q305 VanDerWaalsContact O-CA 3.3Å; D242-Q305 WeakPolarHBondContact O-CA 3.49Å
306Y77.8Confident80.1Confident41 Ų4166.6 Ų66.616%0.16135%0.346CS..EExtended strand (participates in β ladder)trans-127.2126.7177.7179.9-98.2000111.1D242 T243 M244 V245 L276 P298D242-Y306 PolarHBondContact O-N 2.9Å; T243-Y306 CarbonylContact C-O 3.46Å; T243-Y306 VanDerWaalsContact CA-O 3.27Å; T243-Y306 WeakPolarHBondContact CA-O 3.4Å; T243-Y306 HydrophobicContact CG2-CD1 4.17Å; M244-Y306 PolarHBondContact N-O 3.36Å; V245-Y306 HydrophobicContact CG2-CD1 4.23Å; V245-Y306 HydrophobicContact CG2-CE1 3.94Å; L276-Y306 HydrophobicContact CD1-CD2 4.42Å; L276-Y306 HydrophobicContact CD1-CE2 3.58Å; L276-Y306 HydrophobicContact CD2-CD1 4.42Å; L276-Y306 HydrophobicContact CD2-CD2 3.66Å; L276-Y306 HydrophobicContact CD2-CE1 4.28Å; L276-Y306 HydrophobicContact CD2-CE2 3.53Å; L276-Y306 HydrophobicContact CD2-CG 4.11Å; L276-Y306 HydrophobicContact CG-CE2 4.19Å; P298-Y306 HydrophobicContact CG-CD1 3.79Å; P298-Y306 HydrophobicContact CG-CG 3.67Å
307S77.5Confident80.3Confident87 Ų8761.6 Ų61.661%0.60832%0.324SS*.EExtended strand (participates in β ladder)trans-127.1141.1169.9-174.20000111M244M244-S307 WeakPolarHBondContact O-CA 3.35Å; M244-S307 PolarHBondContact O-OG 3.29Å
308S74.6Confident80.5Confident45 Ų4561.4 Ų61.432%0.31532%0.323SS..EExtended strand (participates in β ladder)trans-147.4137.8174.7179.40000109.8M244 V245 T246M244-S308 PolarHBondContact O-N 2.84Å; M244-S308 VanDerWaalsContact O-N 3.09Å; V245-S308 CarbonylContact C-O 3.54Å; V245-S308 WeakPolarHBondContact CA-O 3.3Å; T246-S308 PolarHBondContact N-O 3.09Å
309S71.3Confident80.8Confident66 Ų6662.3 Ų62.346%0.46233%0.329SS..EExtended strand (participates in β ladder)trans-121.1142.9171.662.50000110.9T246T246-S309 CarbonylContact O-C 3.46Å; T246-S309 VanDerWaalsContact O-CA 3.3Å; T246-S309 WeakPolarHBondContact O-CA 3.37Å; T246-S309 WeakPolarHBondContact OG1-CA 3.23Å; T246-S309 VanDerWaalsContact OG1-CB 3.23Å; T246-S309 WeakPolarHBondContact OG1-CB 3.39Å
310G58.7Low81Confident26 Ų2661.9 Ų61.927%0.26832%0.324SS..SBendtrans142.1168.6175.600000114T246 A247T246-G310 PolarHBondContact O-N 2.69Å; A247-G310 VanDerWaalsContact CA-O 3.24Å; A247-G310 WeakPolarHBondContact CA-O 3.41Å; A247-G310 VanDerWaalsContact CB-O 3.29Å; A247-G310 WeakPolarHBondContact CB-O 3.32Å
311P68.2Low80.9Confident105 Ų10556.1 Ų56.168%0.68232%0.324SS*.PPolyproline II helixtrans-65.4140-176.928.3-34.7000111
312F82Confident81.1Confident46 Ų4651.9 Ų51.920%0.20230%0.303CS..PPolyproline II helixtrans-67.5148170-66.7-43.5000111V245 A247 L281 C293 A295 I314V245-F312 HydrophobicContact CG1-CE1 3.7Å; V245-F312 HydrophobicContact CG1-CZ 4.14Å; A247-F312 HydrophobicContact CB-CD1 3.83Å; A247-F312 HydrophobicContact CB-CD2 3.48Å; A247-F312 VanDerWaalsContact CB-CD2 3.48Å; A247-F312 HydrophobicContact CB-CE1 3.67Å; A247-F312 HydrophobicContact CB-CE2 3.32Å; A247-F312 HydrophobicContact CB-CG 3.74Å; A247-F312 HydrophobicContact CB-CZ 3.42Å; A247-F312 VanDerWaalsContact CB-CZ 3.42Å; L281-F312 HydrophobicContact CD1-CD2 4.33Å; L281-F312 HydrophobicContact CD1-CE2 3.74Å; L281-F312 HydrophobicContact CD1-CZ 4.12Å; C293-F312 HydrophobicContact CB-CB 3.78Å; C293-F312 HydrophobicContact CB-CD2 4.25Å; C293-F312 HydrophobicContact CB-CG 4.34Å; A295-F312 HydrophobicContact CB-CD1 3.72Å; A295-F312 HydrophobicContact CB-CE1 3.49Å; A295-F312 VanDerWaalsContact CB-CE1 3.49Å; A295-F312 HydrophobicContact CB-CZ 4.17Å; F312-I314 PolarHBondContact O-N 2.88Å
313R85Confident81.4Confident80 Ų8052.7 Ų52.730%0.30231%0.308SS..EExtended strand (participates in β ladder)trans-70.8118.4173.4177.6-174.5175.1-163.40.7108.8C293 E294 V315 Y357C293-R313 CarbonylContact C-O 3.53Å; C293-R313 WeakPolarHBondContact CA-O 3.3Å; E294-R313 HydrophobicContact CB-CB 4.41Å; E294-R313 PolarHBondContact N-O 3.26Å; E294-R313 PolarHBondContact O-N 2.79Å; E294-R313 IonicContact OE1-CZ 3.62Å; E294-R313 IonicContact OE1-NH1 3.02Å; E294-R313 PolarHBondContact OE1-NH1 3.29Å; R313-V315 PolarHBondContact O-N 3.27Å; R313-Y357 PolarHBondContact NH2-O 2.96Å
314I89.8Confident82.3Confident32 Ų3245.5 Ų45.516%0.16427%0.27CS..EExtended strand (participates in β ladder)trans-74.5118.8170.6-59172.8000108.4F312 K316 A317 Y357 V363F312-I314 PolarHBondContact O-N 2.88Å; I314-K316 WeakPolarHBondContact CG2-O 3.32Å; I314-A317 HydrophobicContact CG2-CB 4.15Å; I314-Y357 HydrophobicContact CG2-CD2 4.44Å; I314-Y357 HydrophobicContact CG2-CE2 4.39Å; I314-V363 HydrophobicContact CB-CG2 4.09Å; I314-V363 HydrophobicContact CD1-CG2 4.45Å; I314-V363 HydrophobicContact CG2-CG1 4.04Å; I314-V363 HydrophobicContact CG2-CG2 4.23Å
315V92.2Very high82.9Confident3 Ų339 Ų392%0.01824%0.24CC..EExtended strand (participates in β ladder)trans-91.4-39.8178.6-174.30000110.6L292 E294 R313 S356 Y357L292-V315 HydrophobicContact CD2-CB 4.33Å; L292-V315 HydrophobicContact CD2-CG1 4.38Å; L292-V315 HydrophobicContact CG-CB 4.35Å; L292-V315 WeakPolarHBondContact O-CA 3.09Å; L292-V315 WeakPolarHBondContact O-CB 3.32Å; L292-V315 PolarHBondContact O-N 2.81Å; E294-V315 HydrophobicContact CB-CG2 3.47Å; E294-V315 VanDerWaalsContact CB-CG2 3.47Å; R313-V315 PolarHBondContact O-N 3.27Å; V315-S356 WeakPolarHBondContact CG1-OG 3.36Å; V315-S356 CarbonylContact O-C 3.47Å; V315-S356 WeakPolarHBondContact O-CA 3.2Å; V315-Y357 WeakPolarHBondContact O-CD2 3.43Å; V315-Y357 PolarHBondContact O-N 2.97Å
316K94.2Very high83.8Confident10 Ų1036.2 Ų36.24%0.04323%0.225CC..EExtended strand (participates in β ladder)trans-146.1149.7178.7-58176.6178.9-176.80108.9L292 I314 E335 L351 L354 S356L292-K316 HydrophobicContact CB-CB 3.96Å; L292-K316 HydrophobicContact CD2-CB 4.43Å; L292-K316 HydrophobicContact CD2-CD 3.86Å; L292-K316 HydrophobicContact CD2-CG 4.16Å; L292-K316 PolarHBondContact N-O 3.06Å; L292-K316 PolarHBondContact O-N 3.14Å; I314-K316 WeakPolarHBondContact CG2-O 3.32Å; K316-E335 IonicContact NZ-OE2 2.77Å; K316-L351 HydrophobicContact CD-CB 4.34Å; K316-L351 PolarHBondContact NZ-O 3.16Å; K316-L354 HydrophobicContact CD-CB 4.03Å; K316-L354 WeakPolarHBondContact CE-O 3.41Å; K316-L354 PolarHBondContact NZ-O 3.08Å; K316-L354 VanDerWaalsContact NZ-O 3.11Å; K316-S356 VanDerWaalsContact CE-OG 3.32Å; K316-S356 WeakPolarHBondContact CE-OG 3.45Å
317A93.2Very high84.8Confident1 Ų134.3 Ų34.31%0.00822%0.218CC..EExtended strand (participates in β ladder)trans-142.8127.6177.700000110.4V289 L290 I314 Y357 V363 V365 K366V289-A317 HydrophobicContact CG1-CB 4.09Å; L290-A317 WeakPolarHBondContact O-CA 3.23Å; I314-A317 HydrophobicContact CG2-CB 4.15Å; A317-Y357 HydrophobicContact CB-CE2 4.32Å; A317-V363 HydrophobicContact CB-CG1 3.73Å; A317-V365 HydrophobicContact CB-CG1 4.47Å; A317-V365 HydrophobicContact CB-CG2 4.13Å; A317-K366 PolarHBondContact O-N 3.05Å
318V94.4Very high85.7Confident0 Ų031.3 Ų31.30%019%0.193CC..EExtended strand (participates in β ladder)trans-128.7128.1-179.8-179.10000109.4L290 F349 L351 L354 K366 V368 L371L290-V318 PolarHBondContact N-O 3.11Å; L290-V318 PolarHBondContact O-N 3.3Å; V318-F349 HydrophobicContact CB-CE2 4.26Å; V318-F349 HydrophobicContact CB-CZ 4.36Å; V318-F349 HydrophobicContact CG1-CE2 4.11Å; V318-F349 HydrophobicContact CG1-CZ 4.04Å; V318-F349 HydrophobicContact CG2-CE2 4.05Å; V318-L351 HydrophobicContact CG2-CD2 4.01Å; V318-L354 HydrophobicContact CG2-CD1 3.56Å; V318-K366 CarbonylContact C-O 2.98Å; V318-K366 VanDerWaalsContact CA-O 3.26Å; V318-K366 WeakPolarHBondContact CA-O 3.18Å; V318-V368 HydrophobicContact CG1-CB 4.1Å; V318-V368 HydrophobicContact CG1-CG2 4.49Å; V318-L371 HydrophobicContact CB-CD1 4.48Å; V318-L371 HydrophobicContact CG1-CD1 3.68Å; V318-L371 HydrophobicContact CG2-CD1 3.89Å
319S91.6Very high86.8Confident25 Ų2529.7 Ų29.718%0.17518%0.18CC..EExtended strand (participates in β ladder)trans-94.6127.5176.9178.90000111.5G288 G321 K366 V368G288-S319 CarbonylContact O-C 3.46Å; G288-S319 WeakPolarHBondContact O-CA 3.46Å; S319-G321 PolarHBondContact OG-N 2.86Å; S319-K366 PolarHBondContact N-O 2.97Å; S319-V368 WeakPolarHBondContact O-CB 3.5Å; S319-V368 PolarHBondContact O-N 3Å
320A86.1Confident88.1Confident5 Ų526.7 Ų26.74%0.04116%0.159CC..  trans-81.6-15.3170.700000113.5G288 S322 I324 M339 C341 R343G288-A320 PolarHBondContact O-N 2.61Å; A320-S322 VanDerWaalsContact C-N 3.26Å; A320-S322 PolarHBondContact O-N 3.41Å; A320-I324 HydrophobicContact CB-CD1 4.45Å; A320-I324 HydrophobicContact CB-CG1 4.1Å; A320-M339 HydrophobicContact CB-CE 3.32Å; A320-M339 HydrophobicContact CB-SD 3.87Å; A320-C341 WeakPolarHBondContact CB-SG 3.49Å; A320-R343 PolarHBondContact O-NE 2.63Å; A320-R343 PolarHBondContact O-NH2 3.04Å
321G77.2Confident89.8Confident69 Ų6926.8 Ų26.871%0.71116%0.155SC*.SBendtrans78.4-1.6-173.600000115.5S319S319-G321 PolarHBondContact OG-N 2.86Å
322S82.6Confident91.1Very high17 Ų1724.6 Ų24.612%0.11914%0.136CC..SBendtrans-153160.6-178.258.30000109.5G288 A320 I324 C341 R343G288-S322 WeakPolarHBondContact CA-O 3.29Å; A320-S322 VanDerWaalsContact C-N 3.26Å; A320-S322 PolarHBondContact O-N 3.41Å; S322-I324 PolarHBondContact O-N 3.35Å; S322-C341 WeakPolarHBondContact OG-CB 3.24Å; S322-R343 PolarHBondContact OG-NE 2.96Å
323E83.8Confident91.7Very high67 Ų6728.6 Ų28.631%0.31315%0.15SC..  trans-53.1135.5-177.6-46.7-170.8168.900111.8L286 C341 Q342L286-E323 HydrophobicContact CD2-CB 4.36Å; L286-E323 HydrophobicContact CD2-CG 4.47Å; L286-E323 VanDerWaalsContact O-CG 3.28Å; L286-E323 WeakPolarHBondContact O-CG 3.21Å; E323-C341 CarbonylContact O-C 3.52Å; E323-C341 WeakPolarHBondContact O-CA 3.34Å; E323-C341 WeakPolarHBondContact O-CB 3.03Å; E323-Q342 HydrophobicContact CB-CG 4.03Å; E323-Q342 VanDerWaalsContact CG-CD 3.48Å; E323-Q342 HydrophobicContact CG-CG 4.31Å; E323-Q342 PolarHBondContact O-N 3.5Å; E323-Q342 PolarHBondContact OE2-NE2 3.39Å
324I90.6Very high92.1Very high0 Ų026.7 Ų26.70%015%0.147CC..EExtended strand (participates in β ladder)trans-92.9120.7178.3-63.8164000108.6S285 L290 A320 S322 A327 M339S285-I324 PolarHBondContact O-N 2.84Å; L290-I324 HydrophobicContact CB-CD1 3.74Å; L290-I324 HydrophobicContact CD1-CD1 4.45Å; A320-I324 HydrophobicContact CB-CD1 4.45Å; A320-I324 HydrophobicContact CB-CG1 4.1Å; S322-I324 PolarHBondContact O-N 3.35Å; I324-A327 HydrophobicContact CG2-CB 4.42Å; I324-M339 HydrophobicContact CD1-CG 4.43Å; I324-M339 HydrophobicContact CD1-SD 3.66Å; I324-M339 HydrophobicContact CG1-CG 4.17Å; I324-M339 HydrophobicContact CG1-SD 3.84Å; I324-M339 HydrophobicContact CG2-CG 3.94Å
325T92Very high92.3Very high1 Ų129 Ų291%0.00616%0.157CC..EExtended strand (participates in β ladder)trans-91.4-39.4-17955.10000111.7K340 G383 F384T325-K340 PolarHBondContact N-O 3.06Å; T325-K340 PolarHBondContact OG1-O 3.13Å; T325-G383 WeakPolarHBondContact CB-O 3.35Å; T325-G383 PolarHBondContact OG1-O 2.79Å; T325-F384 HydrophobicContact CG2-CD1 4.45Å; T325-F384 HydrophobicContact CG2-CE1 4.04Å; T325-F384 HydrophobicContact CG2-CZ 4.22Å
326R97.2Very high92.5Very high34 Ų3429.5 Ų29.513%0.12816%0.16CC..EExtended strand (participates in β ladder)trans-152.1135.8179.8-155.977.2157.2162.5-1.5111.2R328 K340 F384 L386 D581R326-R328 HydrophobicContact CG-CG 4.49Å; R326-K340 PolarHBondContact N-O 2.89Å; R326-K340 PolarHBondContact O-N 2.64Å; R326-F384 VanDerWaalsContact CB-O 3.28Å; R326-F384 WeakPolarHBondContact CB-O 3.17Å; R326-F384 VanDerWaalsContact CD-O 3.31Å; R326-F384 WeakPolarHBondContact CD-O 3.4Å; R326-F384 WeakPolarHBondContact CG-O 3.34Å; R326-L386 HydrophobicContact CB-CB 4.02Å; R326-L386 HydrophobicContact CB-CD2 4.33Å; R326-L386 HydrophobicContact CG-CB 3.73Å; R326-L386 HydrophobicContact CG-CD2 4.45Å; R326-D581 IonicContact CZ-OD1 3.71Å; R326-D581 IonicContact NH1-OD1 2.76Å; R326-D581 PolarHBondContact NH1-OD1 2.76Å; R326-D581 IonicContact NH1-OD2 2.69Å; R326-D581 PolarHBondContact NH1-OD2 3.4Å; R326-D581 VanDerWaalsContact NH1-OD2 3.09Å; R326-D581 IonicContact NH2-OD1 2.72Å
327A97.9Very high92.7Very high1 Ų129 Ų291%0.00816%0.158CC..EExtended strand (participates in β ladder)trans-133.7134.8170.800000111S255 L282 L290 I324 A338S255-A327 PolarHBondContact OG-N 3.42Å; S255-A327 PolarHBondContact OG-O 3.5Å; L282-A327 HydrophobicContact CD2-CB 3.86Å; L282-A327 HydrophobicContact CG-CB 4.37Å; L290-A327 HydrophobicContact CD1-CB 3.49Å; L290-A327 VanDerWaalsContact CD1-CB 3.49Å; I324-A327 HydrophobicContact CG2-CB 4.42Å; A327-A338 CarbonylContact C-O 3.52Å; A327-A338 VanDerWaalsContact CA-O 3.28Å; A327-A338 WeakPolarHBondContact CA-O 3.36Å
328R98.1Very high92.9Very high25 Ų2529 Ų299%0.09416%0.158CC..EExtended strand (participates in β ladder)trans-140.7138.1-177.2-64-65.4179-114.920.9112.2S255 V256 Q257 R326 A338 L386 W388 D581S255-R328 PolarHBondContact OG-NH1 3.24Å; V256-R328 PolarHBondContact O-NH1 3.01Å; Q257-R328 VanDerWaalsContact CD-CD 3.48Å; Q257-R328 VanDerWaalsContact OE1-CA 3.25Å; R326-R328 HydrophobicContact CG-CG 4.49Å; R328-A338 PolarHBondContact N-O 3Å; R328-A338 PolarHBondContact O-N 2.96Å; R328-L386 HydrophobicContact CB-CD2 4.44Å; R328-L386 HydrophobicContact CG-CD2 4.46Å; R328-W388 PolarHBondContact O-NE1 2.75Å; R328-D581 IonicContact CZ-OD2 3.88Å; R328-D581 IonicContact NH1-OD2 3.96Å; R328-D581 PolarHBondContact NH1-OD2 3.21Å; R328-D581 IonicContact NH2-OD1 2.67Å; R328-D581 PolarHBondContact NH2-OD1 2.83Å; R328-D581 IonicContact NH2-OD2 2.89Å; R328-D581 PolarHBondContact NH2-OD2 3.13Å
329Y97.5Very high93Very high10 Ų1029 Ų294%0.03916%0.158CC..EExtended strand (participates in β ladder)trans-82.3150.3173.173.5-95000112Q257 W258 L259 P260 P331 P334 V336Q257-Y329 HydrophobicContact CG-CD1 4.13Å; Q257-Y329 HydrophobicContact CG-CE1 3.94Å; W258-Y329 WeakPolarHBondContact O-CE1 3.38Å; L259-Y329 HydrophobicContact CG-CD1 4.47Å; P260-Y329 HydrophobicContact CG-CE2 4.26Å; Y329-P331 WeakPolarHBondContact O-CD 3.46Å; Y329-P334 HydrophobicContact CD2-CB 3.85Å; Y329-P334 HydrophobicContact CD2-CG 4.18Å; Y329-P334 HydrophobicContact CE2-CB 4.38Å; Y329-P334 HydrophobicContact CE2-CG 4.36Å; Y329-P334 HydrophobicContact CG-CB 4.39Å; Y329-V336 WeakPolarHBondContact CA-O 3.21Å
330M97.4Very high93.2Very high3 Ų327.8 Ų27.82%0.01515%0.15CC..EExtended strand (participates in β ladder)trans-74.8120.5172.7-179.7-172.1-65.300110.2Q332 R333 P334 V336 W388 T393 V410M330-Q332 VanDerWaalsContact C-N 3.28Å; M330-Q332 VanDerWaalsContact CG-OE1 3.26Å; M330-Q332 PolarHBondContact O-N 3.46Å; M330-Q332 VanDerWaalsContact O-N 3.14Å; M330-R333 CarbonylContact O-C 3.31Å; M330-R333 PolarHBondContact O-N 2.72Å; M330-R333 HydrophobicContact SD-CB 4.02Å; M330-R333 HydrophobicContact SD-CG 4.49Å; M330-P334 WeakPolarHBondContact O-CA 3.18Å; M330-V336 HydrophobicContact CB-CB 4.23Å; M330-V336 HydrophobicContact CE-CB 4.42Å; M330-V336 HydrophobicContact CE-CG1 3.94Å; M330-V336 PolarHBondContact N-O 2.7Å; M330-W388 HydrophobicContact CB-CD2 3.98Å; M330-W388 HydrophobicContact CB-CE3 4.26Å; M330-W388 HydrophobicContact CB-CG 4.42Å; M330-W388 HydrophobicContact CB-CZ2 4.25Å; M330-W388 HydrophobicContact CE-CE3 3.98Å; M330-W388 HydrophobicContact CE-CH2 3.47Å; M330-W388 VanDerWaalsContact CE-CH2 3.47Å; M330-W388 HydrophobicContact CE-CZ2 4.17Å; M330-W388 HydrophobicContact CE-CZ3 3.37Å; M330-W388 HydrophobicContact CG-CD2 4.3Å; M330-W388 HydrophobicContact CG-CE3 4.14Å; M330-W388 HydrophobicContact CG-CZ3 4.46Å; M330-T393 HydrophobicContact SD-CG2 3.84Å; M330-V410 HydrophobicContact CE-CG2 3.94Å
331P95Very high93.3Very high29 Ų2927.5 Ų27.519%0.18815%0.148CC..THydrogen-bonded Turntrans-54.2-38.7-174.3-31.738.7000115Y329 W388 E390Y329-P331 WeakPolarHBondContact O-CD 3.46Å; P331-W388 HydrophobicContact CG-CB 4.31Å; P331-E390 VanDerWaalsContact CB-OE2 3.29Å; P331-E390 WeakPolarHBondContact CB-OE2 3.15Å; P331-E390 HydrophobicContact CG-CG 4.46Å; P331-E390 VanDerWaalsContact CG-OE2 3.3Å; P331-E390 WeakPolarHBondContact CG-OE2 3.44Å
332Q94.9Very high93.5Very high59 Ų5928.4 Ų28.428%0.27613%0.133SC..THydrogen-bonded Turntrans-80-21.1-178.2-49.883.19.500112.6M330 N389 E390 T393M330-Q332 VanDerWaalsContact C-N 3.28Å; M330-Q332 VanDerWaalsContact CG-OE1 3.26Å; M330-Q332 PolarHBondContact O-N 3.46Å; M330-Q332 VanDerWaalsContact O-N 3.14Å; Q332-N389 PolarHBondContact NE2-O 3.48Å; Q332-E390 PolarHBondContact NE2-O 3.48Å; Q332-T393 HydrophobicContact CB-CG2 4.23Å; Q332-T393 WeakPolarHBondContact CG-OG1 3.43Å
333R94.4Very high93.5Very high130 Ų13030.5 Ų30.549%0.49114%0.139SC..EExtended strand (participates in β ladder)trans-14281.2178.2-70.3179.956.3166.6-3.2110.4M330 E335 V336M330-R333 CarbonylContact O-C 3.31Å; M330-R333 PolarHBondContact O-N 2.72Å; M330-R333 HydrophobicContact SD-CB 4.02Å; M330-R333 HydrophobicContact SD-CG 4.49Å; R333-E335 PolarHBondContact O-N 3.45Å; R333-V336 HydrophobicContact CB-CB 4.46Å; R333-V336 HydrophobicContact CB-CG2 4.06Å; R333-V336 WeakPolarHBondContact O-CB 3.26Å; R333-V336 PolarHBondContact O-N 2.99Å
334P95Very high93.8Very high39 Ų3929.4 Ų29.425%0.25314%0.137SC..EExtended strand (participates in β ladder)trans-61.6-14.9-172.7-2635.3000116.2P260 Y329 M330 V336P260-P334 HydrophobicContact CG-CB 3.68Å; P260-P334 HydrophobicContact CG-CG 3.38Å; Y329-P334 HydrophobicContact CD2-CB 3.85Å; Y329-P334 HydrophobicContact CD2-CG 4.18Å; Y329-P334 HydrophobicContact CE2-CB 4.38Å; Y329-P334 HydrophobicContact CE2-CG 4.36Å; Y329-P334 HydrophobicContact CG-CB 4.39Å; M330-P334 WeakPolarHBondContact O-CA 3.18Å; P334-V336 VanDerWaalsContact C-N 3.27Å
335E93.6Very high93.8Very high80 Ų8031.8 Ų31.837%0.37415%0.148SC..EExtended strand (participates in β ladder)trans-72.3-20.5172.1-61.5-92.7-163.700112.4K316 R333 N350 L351 G352K316-E335 IonicContact NZ-OE2 2.77Å; R333-E335 PolarHBondContact O-N 3.45Å; E335-N350 WeakPolarHBondContact CB-OD1 2.76Å; E335-N350 CarbonylContact O-C 3.54Å; E335-N350 WeakPolarHBondContact O-CA 3.21Å; E335-N350 PolarHBondContact O-OD1 2.78Å; E335-L351 PolarHBondContact O-N 2.77Å; E335-G352 WeakPolarHBondContact OE2-CA 3.28Å; E335-G352 PolarHBondContact OE2-N 2.75Å
336V95.8Very high94.1Very high14 Ų1431.7 Ų31.79%0.08515%0.148CC..EExtended strand (participates in β ladder)trans-92125.1177.7-178.20000109.1Y329 M330 R333 P334 V348 F349 N350Y329-V336 WeakPolarHBondContact CA-O 3.21Å; M330-V336 HydrophobicContact CB-CB 4.23Å; M330-V336 HydrophobicContact CE-CB 4.42Å; M330-V336 HydrophobicContact CE-CG1 3.94Å; M330-V336 PolarHBondContact N-O 2.7Å; R333-V336 HydrophobicContact CB-CB 4.46Å; R333-V336 HydrophobicContact CB-CG2 4.06Å; R333-V336 WeakPolarHBondContact O-CB 3.26Å; R333-V336 PolarHBondContact O-N 2.99Å; P334-V336 VanDerWaalsContact C-N 3.27Å; V336-V348 HydrophobicContact CG1-CG1 3.7Å; V336-F349 WeakPolarHBondContact CA-O 2.79Å; V336-N350 HydrophobicContact CG2-CB 4.44Å
337V97.7Very high94Very high0 Ų030.1 Ų30.10%014%0.142CC..EExtended strand (participates in β ladder)trans-125.2136-174.5175.50000110.1L282 L290 V348 F349 L351L282-V337 HydrophobicContact CD2-CG1 3.68Å; L282-V337 HydrophobicContact CD2-CG2 4.22Å; L290-V337 HydrophobicContact CD2-CG1 4.03Å; V337-V348 VanDerWaalsContact O-CA 3.31Å; V337-V348 WeakPolarHBondContact O-CA 3.47Å; V337-F349 PolarHBondContact N-O 3.06Å; V337-F349 PolarHBondContact O-N 3.3Å; V337-L351 HydrophobicContact CB-CD1 4.49Å; V337-L351 HydrophobicContact CG2-CD1 3.62Å; V337-L351 HydrophobicContact CG2-CG 4.13Å
338A98Very high93.9Very high0 Ų030.3 Ų30.30%014%0.143CC..EExtended strand (participates in β ladder)trans-97142.3164.400000109.9A327 R328 V346 F347 V348 L386 W388 L396A327-A338 CarbonylContact C-O 3.52Å; A327-A338 VanDerWaalsContact CA-O 3.28Å; A327-A338 WeakPolarHBondContact CA-O 3.36Å; R328-A338 PolarHBondContact N-O 3Å; R328-A338 PolarHBondContact O-N 2.96Å; A338-V346 HydrophobicContact CB-CG1 4.26Å; A338-F347 CarbonylContact C-O 3.47Å; A338-F347 VanDerWaalsContact CA-O 3.28Å; A338-F347 WeakPolarHBondContact CA-O 3.34Å; A338-V348 HydrophobicContact CB-CG2 4.01Å; A338-L386 HydrophobicContact CB-CD1 4.32Å; A338-L386 HydrophobicContact CB-CD2 3.95Å; A338-L386 HydrophobicContact CB-CG 4.41Å; A338-W388 HydrophobicContact CB-CZ2 3.52Å; A338-L396 HydrophobicContact CB-CD1 4.09Å; A338-L396 HydrophobicContact CB-CD2 3.65Å
339M96.7Very high93.7Very high0 Ų029.4 Ų29.40%014%0.14CC..EExtended strand (participates in β ladder)trans-139119.7-178.2179.4-176.770.300109.4L290 A320 I324 F347 F349 V368L290-M339 HydrophobicContact CB-SD 4.07Å; L290-M339 HydrophobicContact CD2-SD 4.19Å; A320-M339 HydrophobicContact CB-CE 3.32Å; A320-M339 HydrophobicContact CB-SD 3.87Å; I324-M339 HydrophobicContact CD1-CG 4.43Å; I324-M339 HydrophobicContact CD1-SD 3.66Å; I324-M339 HydrophobicContact CG1-CG 4.17Å; I324-M339 HydrophobicContact CG1-SD 3.84Å; I324-M339 HydrophobicContact CG2-CG 3.94Å; M339-F347 HydrophobicContact CB-CB 4.45Å; M339-F347 HydrophobicContact CE-CB 3.9Å; M339-F347 HydrophobicContact CE-CD2 4.23Å; M339-F347 HydrophobicContact CE-CG 4.12Å; M339-F347 PolarHBondContact N-O 3.19Å; M339-F347 PolarHBondContact O-N 2.85Å; M339-F349 HydrophobicContact CB-CE1 4.19Å; M339-F349 HydrophobicContact CE-CE1 3.97Å; M339-F349 HydrophobicContact CE-CZ 4.49Å; M339-F349 HydrophobicContact SD-CE1 4.33Å; M339-F349 HydrophobicContact SD-CZ 4.38Å; M339-V368 HydrophobicContact CE-CG2 4.43Å
340K95.3Very high93.6Very high0 Ų030.8 Ų30.80%015%0.148CC..EExtended strand (participates in β ladder)trans-101.4142.9169-168.5156.2171.5560109.3T325 R326 V346 S381 G383 L386 G399T325-K340 PolarHBondContact N-O 3.06Å; T325-K340 PolarHBondContact OG1-O 3.13Å; R326-K340 PolarHBondContact N-O 2.89Å; R326-K340 PolarHBondContact O-N 2.64Å; K340-V346 HydrophobicContact CB-CG2 4.32Å; K340-V346 HydrophobicContact CD-CG2 4.03Å; K340-V346 HydrophobicContact CG-CG2 4.25Å; K340-S381 PolarHBondContact NZ-O 3.39Å; K340-S381 VanDerWaalsContact NZ-O 3.11Å; K340-G383 VanDerWaalsContact CE-CA 3.46Å; K340-G383 VanDerWaalsContact CE-N 3.29Å; K340-G383 WeakPolarHBondContact CG-O 3.37Å; K340-L386 HydrophobicContact CB-CD2 4.4Å; K340-G399 WeakPolarHBondContact CE-O 3.24Å
341C88.4Confident93.4Very high0 Ų031 Ų310%015%0.149CC..EExtended strand (participates in β ladder)trans-135.2-176.9-173.8-53.80000109.2A320 S322 E323 R343A320-C341 WeakPolarHBondContact CB-SG 3.49Å; S322-C341 WeakPolarHBondContact OG-CB 3.24Å; E323-C341 CarbonylContact O-C 3.52Å; E323-C341 WeakPolarHBondContact O-CA 3.34Å; E323-C341 WeakPolarHBondContact O-CB 3.03Å; C341-R343 PolarHBondContact O-N 3.46Å
342Q81.8Confident93.1Very high87 Ų8731.2 Ų31.241%0.40716%0.156SC..SBendtrans-55.8-17.6166.1-88.8179.3-1100114.4E323 E382E323-Q342 HydrophobicContact CB-CG 4.03Å; E323-Q342 VanDerWaalsContact CG-CD 3.48Å; E323-Q342 HydrophobicContact CG-CG 4.31Å; E323-Q342 PolarHBondContact O-N 3.5Å; E323-Q342 PolarHBondContact OE2-NE2 3.39Å; Q342-E382 WeakPolarHBondContact CG-OE2 3.36Å
343R83.2Confident92.9Very high62 Ų6234 Ų3423%0.23417%0.173CC..SBendtrans-83.6149.6175.8-64.3-175.2-65.194.7-3110.7A320 S322 C341 E345 F347A320-R343 PolarHBondContact O-NE 2.63Å; A320-R343 PolarHBondContact O-NH2 3.04Å; S322-R343 PolarHBondContact OG-NE 2.96Å; C341-R343 PolarHBondContact O-N 3.46Å; R343-E345 VanDerWaalsContact C-N 3.28Å; R343-E345 IonicContact NH1-OE2 3.85Å; R343-E345 PolarHBondContact NH1-OE2 3.09Å; R343-E345 PolarHBondContact O-N 3.44Å; R343-F347 VanDerWaalsContact CZ-CZ 3.45Å
344P89.1Confident92.7Very high43 Ų4328.7 Ų28.728%0.27915%0.154SC..SBendtrans-61.3-35.5-177.6-23.333.7000113.6H379 S381P344-H379 VanDerWaalsContact CB-O 3.27Å; P344-H379 WeakPolarHBondContact CB-O 3.39Å; P344-H379 WeakPolarHBondContact O-CB 3.35Å; P344-S381 WeakPolarHBondContact CA-O 3.38Å
345E92.1Very high92.4Very high50 Ų5034.4 Ų34.423%0.23417%0.17CC..SBendtrans-75.1145.1-176.1-51.991.3164.500113.4R343 F347 L376 K377R343-E345 VanDerWaalsContact C-N 3.28Å; R343-E345 IonicContact NH1-OE2 3.85Å; R343-E345 PolarHBondContact NH1-OE2 3.09Å; R343-E345 PolarHBondContact O-N 3.44Å; E345-F347 HydrophobicContact CB-CE2 4.05Å; E345-F347 HydrophobicContact CB-CZ 4.27Å; E345-F347 WeakPolarHBondContact O-CE2 3.43Å; E345-L376 WeakPolarHBondContact CA-O 2.9Å; E345-K377 HydrophobicContact CG-CG 4.3Å
346V96.4Very high92.2Very high0 Ų032.7 Ų32.70%017%0.167CC..EExtended strand (participates in β ladder)trans-93.6134.1168-179.70000109.4A338 K340 L376 L386 L396 W408A338-V346 HydrophobicContact CB-CG1 4.26Å; K340-V346 HydrophobicContact CB-CG2 4.32Å; K340-V346 HydrophobicContact CD-CG2 4.03Å; K340-V346 HydrophobicContact CG-CG2 4.25Å; V346-L376 HydrophobicContact CB-CB 4.1Å; V346-L376 HydrophobicContact CB-CD1 4.15Å; V346-L376 HydrophobicContact CB-CG 4.3Å; V346-L376 HydrophobicContact CG1-CD1 4.1Å; V346-L376 PolarHBondContact N-O 3.16Å; V346-L376 PolarHBondContact O-N 3.11Å; V346-L386 HydrophobicContact CG1-CD1 3.96Å; V346-L386 HydrophobicContact CG2-CD1 4.47Å; V346-L396 HydrophobicContact CG1-CD2 4.09Å; V346-W408 HydrophobicContact CG2-CH2 4.29Å
347F95.6Very high91.8Very high0 Ų033.4 Ų33.40%017%0.168CC..EExtended strand (participates in β ladder)trans-99.5128.2178.6-69.9-92.2000110.3A338 M339 R343 E345 F349 V368 H373 L374 K375A338-F347 CarbonylContact C-O 3.47Å; A338-F347 VanDerWaalsContact CA-O 3.28Å; A338-F347 WeakPolarHBondContact CA-O 3.34Å; M339-F347 HydrophobicContact CB-CB 4.45Å; M339-F347 HydrophobicContact CE-CB 3.9Å; M339-F347 HydrophobicContact CE-CD2 4.23Å; M339-F347 HydrophobicContact CE-CG 4.12Å; M339-F347 PolarHBondContact N-O 3.19Å; M339-F347 PolarHBondContact O-N 2.85Å; R343-F347 VanDerWaalsContact CZ-CZ 3.45Å; E345-F347 HydrophobicContact CB-CE2 4.05Å; E345-F347 HydrophobicContact CB-CZ 4.27Å; E345-F347 WeakPolarHBondContact O-CE2 3.43Å; F347-F349 HydrophobicContact CB-CD1 4.19Å; F347-F349 HydrophobicContact CB-CE1 4.2Å; F347-V368 HydrophobicContact CB-CG2 4.24Å; F347-V368 HydrophobicContact CD1-CG1 4.04Å; F347-V368 HydrophobicContact CD1-CG2 3.66Å; F347-V368 HydrophobicContact CE1-CG1 4.13Å; F347-V368 HydrophobicContact CE1-CG2 4.49Å; F347-V368 HydrophobicContact CG-CG2 4.13Å; F347-H373 AromaticContact CD1-CD2 3.77Å; F347-H373 AromaticContact CE1-CD2 3.95Å; F347-L374 WeakPolarHBondContact CA-O 3.44Å; F347-K375 HydrophobicContact CD1-CG 4.35Å; F347-K375 HydrophobicContact CE1-CD 3.99Å; F347-K375 HydrophobicContact CE1-CG 3.75Å; F347-K375 HydrophobicContact CZ-CD 4.24Å; F347-K375 HydrophobicContact CZ-CG 4.23Å
348V96.2Very high91.1Very high6 Ų638.9 Ų38.94%0.03619%0.194CC..EExtended strand (participates in β ladder)trans-117.8125170.7-1790000109.7V336 V337 A338 H373 L374 L376 W388 L396 V410V336-V348 HydrophobicContact CG1-CG1 3.7Å; V337-V348 VanDerWaalsContact O-CA 3.31Å; V337-V348 WeakPolarHBondContact O-CA 3.47Å; A338-V348 HydrophobicContact CB-CG2 4.01Å; V348-H373 CarbonylContact O-C 3.52Å; V348-H373 WeakPolarHBondContact O-CA 3.26Å; V348-L374 HydrophobicContact CB-CB 4.28Å; V348-L374 PolarHBondContact N-O 2.96Å; V348-L374 PolarHBondContact O-N 2.95Å; V348-L376 HydrophobicContact CG2-CD1 3.7Å; V348-L376 HydrophobicContact CG2-CD2 4.34Å; V348-L376 HydrophobicContact CG2-CG 4.06Å; V348-W388 HydrophobicContact CG1-CH2 4.07Å; V348-W388 HydrophobicContact CG1-CZ2 4.19Å; V348-W388 HydrophobicContact CG2-CH2 4.23Å; V348-W388 HydrophobicContact CG2-CZ2 4.29Å; V348-L396 HydrophobicContact CG2-CD2 4.18Å; V348-V410 HydrophobicContact CG2-CG1 4.31Å
349F94.8Very high89.8Confident6 Ų646.3 Ų46.33%0.02622%0.222CC..EExtended strand (participates in β ladder)trans-148.9162179.853.4-86.5000111.5L290 V318 V336 V337 M339 F347 L351 V368 L371 H373L290-F349 HydrophobicContact CD2-CE2 4.12Å; L290-F349 HydrophobicContact CD2-CZ 3.56Å; V318-F349 HydrophobicContact CB-CE2 4.26Å; V318-F349 HydrophobicContact CB-CZ 4.36Å; V318-F349 HydrophobicContact CG1-CE2 4.11Å; V318-F349 HydrophobicContact CG1-CZ 4.04Å; V318-F349 HydrophobicContact CG2-CE2 4.05Å; V336-F349 WeakPolarHBondContact CA-O 2.79Å; V337-F349 PolarHBondContact N-O 3.06Å; V337-F349 PolarHBondContact O-N 3.3Å; M339-F349 HydrophobicContact CB-CE1 4.19Å; M339-F349 HydrophobicContact CE-CE1 3.97Å; M339-F349 HydrophobicContact CE-CZ 4.49Å; M339-F349 HydrophobicContact SD-CE1 4.33Å; M339-F349 HydrophobicContact SD-CZ 4.38Å; F347-F349 HydrophobicContact CB-CD1 4.19Å; F347-F349 HydrophobicContact CB-CE1 4.2Å; F349-L351 HydrophobicContact CD2-CD2 4.23Å; F349-L351 HydrophobicContact CD2-CG 4.46Å; F349-L351 HydrophobicContact CE2-CD2 3.72Å; F349-L351 HydrophobicContact CE2-CG 4.16Å; F349-V368 HydrophobicContact CD1-CG2 3.94Å; F349-V368 HydrophobicContact CE1-CG2 4.06Å; F349-L371 HydrophobicContact CD2-CD1 4.05Å; F349-L371 HydrophobicContact CE2-CD1 4.48Å; F349-L371 HydrophobicContact CG-CD1 4.44Å; F349-H373 HydrophobicContact CB-CB 3.98Å
350N94Very high88.8Confident39 Ų3955.2 Ų55.221%0.20926%0.263CS..EExtended strand (participates in β ladder)trans-101.3105.1-178-175.9-3.9000110.4E335 V336 G352 L353E335-N350 WeakPolarHBondContact CB-OD1 2.76Å; E335-N350 CarbonylContact O-C 3.54Å; E335-N350 WeakPolarHBondContact O-CA 3.21Å; E335-N350 PolarHBondContact O-OD1 2.78Å; V336-N350 HydrophobicContact CG2-CB 4.44Å; N350-G352 PolarHBondContact O-N 2.8Å; N350-G352 WeakPolarHBondContact OD1-CA 3.32Å; N350-G352 PolarHBondContact OD1-N 2.84Å; N350-L353 HydrophobicContact CB-CD1 4.01Å; N350-L353 HydrophobicContact CB-CG 4.08Å; N350-L353 PolarHBondContact O-N 3.07Å
351L93.2Very high87.8Confident7 Ų758.5 Ų58.54%0.03728%0.279CS..G310 helixtrans-60.7-27.4174.7-74.5177.9000112.2L282 K316 V318 E335 V337 F349 L353 L354L282-L351 HydrophobicContact CD1-CD1 4.12Å; K316-L351 HydrophobicContact CD-CB 4.34Å; K316-L351 PolarHBondContact NZ-O 3.16Å; V318-L351 HydrophobicContact CG2-CD2 4.01Å; E335-L351 PolarHBondContact O-N 2.77Å; V337-L351 HydrophobicContact CB-CD1 4.49Å; V337-L351 HydrophobicContact CG2-CD1 3.62Å; V337-L351 HydrophobicContact CG2-CG 4.13Å; F349-L351 HydrophobicContact CD2-CD2 4.23Å; F349-L351 HydrophobicContact CD2-CG 4.46Å; F349-L351 HydrophobicContact CE2-CD2 3.72Å; F349-L351 HydrophobicContact CE2-CG 4.16Å; L351-L353 PolarHBondContact O-N 2.8Å; L351-L353 VanDerWaalsContact O-N 3.16Å; L351-L354 HydrophobicContact CD2-CD1 4.01Å; L351-L354 WeakPolarHBondContact O-CB 3.42Å; L351-L354 PolarHBondContact O-N 3.32Å
352G90.2Very high87.2Confident33 Ų3366.9 Ų66.934%0.3432%0.318SS..G310 helixtrans-61.7-22.1179.700000114.4E335 N350 L354E335-G352 WeakPolarHBondContact OE2-CA 3.28Å; E335-G352 PolarHBondContact OE2-N 2.75Å; N350-G352 PolarHBondContact O-N 2.8Å; N350-G352 WeakPolarHBondContact OD1-CA 3.32Å; N350-G352 PolarHBondContact OD1-N 2.84Å; G352-L354 PolarHBondContact O-N 3.42Å
353L89.8Confident87.2Confident119 Ų11965.8 Ų65.862%0.62332%0.317SS*.G310 helixtrans-76.6-10175.1-59.5177.7000113N350 L351N350-L353 HydrophobicContact CB-CD1 4.01Å; N350-L353 HydrophobicContact CB-CG 4.08Å; N350-L353 PolarHBondContact O-N 3.07Å; L351-L353 PolarHBondContact O-N 2.8Å; L351-L353 VanDerWaalsContact O-N 3.16Å
354L90.6Very high87.2Confident18 Ų1867.5 Ų67.59%0.09433%0.334CS..SBendtrans-93.6133.4178.6-61.5-178.8000111.7K316 V318 L351 G352 K366 L371K316-L354 HydrophobicContact CD-CB 4.03Å; K316-L354 WeakPolarHBondContact CE-O 3.41Å; K316-L354 PolarHBondContact NZ-O 3.08Å; K316-L354 VanDerWaalsContact NZ-O 3.11Å; V318-L354 HydrophobicContact CG2-CD1 3.56Å; L351-L354 HydrophobicContact CD2-CD1 4.01Å; L351-L354 WeakPolarHBondContact O-CB 3.42Å; L351-L354 PolarHBondContact O-N 3.32Å; G352-L354 PolarHBondContact O-N 3.42Å; L354-K366 HydrophobicContact CD2-CD 3.63Å; L354-L371 HydrophobicContact CD1-CD1 4.25Å; L354-L371 HydrophobicContact CD2-CD2 3.62Å
355R89Confident87Confident158 Ų15868.6 Ų68.660%0.59634%0.34SS*.PPolyproline II helixtrans-60.1137.5165.6-177.3176175.5-131.6-4.9109.2E358 E361R355-E358 IonicContact NH2-OE1 2.88Å; R355-E358 PolarHBondContact NH2-OE1 2.92Å; R355-E361 IonicContact CZ-OE1 3.59Å; R355-E361 VanDerWaalsContact CZ-OE1 3.3Å; R355-E361 IonicContact NH1-OE1 3.16Å; R355-E361 PolarHBondContact NH1-OE1 2.81Å; R355-E361 IonicContact NH1-OE2 3.3Å; R355-E361 IonicContact NH2-OE1 2.93Å; R355-E361 PolarHBondContact NH2-OE1 3.12Å; R355-E361 IonicContact NH2-OE2 2.8Å
356S88.7Confident86.8Confident44 Ų4470.4 Ų70.431%0.30835%0.347SS..PPolyproline II helixtrans-82.5138.8172.7-59.30000109.9V315 K316V315-S356 WeakPolarHBondContact CG1-OG 3.36Å; V315-S356 CarbonylContact O-C 3.47Å; V315-S356 WeakPolarHBondContact O-CA 3.2Å; K316-S356 VanDerWaalsContact CE-OG 3.32Å; K316-S356 WeakPolarHBondContact CE-OG 3.45Å
357Y87.2Confident86.5Confident29 Ų2977.7 Ų77.711%0.11438%0.378CS..PPolyproline II helixtrans-65.8140177.2-55.8-61.7000112R313 I314 V315 A317 E361 V363 V364R313-Y357 PolarHBondContact NH2-O 2.96Å; I314-Y357 HydrophobicContact CG2-CD2 4.44Å; I314-Y357 HydrophobicContact CG2-CE2 4.39Å; V315-Y357 WeakPolarHBondContact O-CD2 3.43Å; V315-Y357 PolarHBondContact O-N 2.97Å; A317-Y357 HydrophobicContact CB-CE2 4.32Å; Y357-E361 WeakPolarHBondContact CA-OE2 3.45Å; Y357-V363 HydrophobicContact CD2-CG1 4.36Å; Y357-V363 HydrophobicContact CD2-CG2 4.26Å; Y357-V363 HydrophobicContact CE2-CB 4.35Å; Y357-V363 HydrophobicContact CE2-CG1 3.74Å; Y357-V363 HydrophobicContact CE2-CG2 4.45Å; Y357-V364 HydrophobicContact CE1-CB 4.4Å; Y357-V364 VanDerWaalsContact OH-C 3.27Å; Y357-V364 PolarHBondContact OH-N 2.99Å; Y357-V364 PolarHBondContact OH-O 2.93Å
358E82.2Confident86.2Confident115 Ų11577.7 Ų77.754%0.53738%0.378SS..PPolyproline II helixtrans-75161.9167.3-63.3-176.9-162.700111.1R355 H360 E361R355-E358 IonicContact NH2-OE1 2.88Å; R355-E358 PolarHBondContact NH2-OE1 2.92Å; E358-H360 PolarHBondContact O-N 3.13Å; E358-H360 VanDerWaalsContact O-N 3.11Å; E358-E361 HydrophobicContact CB-CG 3.95Å; E358-E361 PolarHBondContact N-OE2 3.25Å; E358-E361 PolarHBondContact O-N 2.73Å
359R72.4Confident85.8Confident157 Ų15782 Ų8259%0.59240%0.401SS*.THydrogen-bonded Turntrans-61.3-25.5-169.8-76.5-170.8-175.6166.29.6115.1R278R278-R359 VanDerWaalsContact NH2-NH2 3.12Å
360H74.5Confident85.5Confident186 Ų18685.6 Ų85.686%0.86143%0.428SS*.THydrogen-bonded Turntrans-110.52.5-176.6-52.2104.2000112.4E358E358-H360 PolarHBondContact O-N 3.13Å; E358-H360 VanDerWaalsContact O-N 3.11Å
361E74.6Confident85.2Confident70 Ų7085 Ų8533%0.32742%0.424SS..SBendtrans-78.1144.3176.7-76.5178.5160.900110.3R355 Y357 E358R355-E361 IonicContact CZ-OE1 3.59Å; R355-E361 VanDerWaalsContact CZ-OE1 3.3Å; R355-E361 IonicContact NH1-OE1 3.16Å; R355-E361 PolarHBondContact NH1-OE1 2.81Å; R355-E361 IonicContact NH1-OE2 3.3Å; R355-E361 IonicContact NH2-OE1 2.93Å; R355-E361 PolarHBondContact NH2-OE1 3.12Å; R355-E361 IonicContact NH2-OE2 2.8Å; Y357-E361 WeakPolarHBondContact CA-OE2 3.45Å; E358-E361 HydrophobicContact CB-CG 3.95Å; E358-E361 PolarHBondContact N-OE2 3.25Å; E358-E361 PolarHBondContact O-N 2.73Å
362Q77Confident84.9Confident176 Ų17690.9 Ų90.982%0.82246%0.455SS*.  trans-69.5138.8168.7-72.5-175.9-11.400110.1V364Q362-V364 PolarHBondContact O-N 3.42Å
363V80.4Confident85Confident64 Ų6490.1 Ų90.139%0.38844%0.443SS..  trans-71.6114.9178176.80000109.4I314 A317 Y357 V365I314-V363 HydrophobicContact CB-CG2 4.09Å; I314-V363 HydrophobicContact CD1-CG2 4.45Å; I314-V363 HydrophobicContact CG2-CG1 4.04Å; I314-V363 HydrophobicContact CG2-CG2 4.23Å; A317-V363 HydrophobicContact CB-CG1 3.73Å; Y357-V363 HydrophobicContact CD2-CG1 4.36Å; Y357-V363 HydrophobicContact CD2-CG2 4.26Å; Y357-V363 HydrophobicContact CE2-CB 4.35Å; Y357-V363 HydrophobicContact CE2-CG1 3.74Å; Y357-V363 HydrophobicContact CE2-CG2 4.45Å; V363-V365 HydrophobicContact CG1-CG2 4.45Å
364V82.8Confident85.2Confident98 Ų9886.2 Ų86.259%0.59442%0.423SS*.  trans-102.394.6178.6-178.10000110.4Y357 Q362 K366Y357-V364 HydrophobicContact CE1-CB 4.4Å; Y357-V364 VanDerWaalsContact OH-C 3.27Å; Y357-V364 PolarHBondContact OH-N 2.99Å; Y357-V364 PolarHBondContact OH-O 2.93Å; Q362-V364 PolarHBondContact O-N 3.42Å; V364-K366 PolarHBondContact O-N 3.19Å; V364-K366 VanDerWaalsContact O-N 3.09Å
365V85.1Confident85.3Confident65 Ų6588 Ų8839%0.39443%0.43SS..  trans-62.4115.3-177.5-171.70000111V289 A317 V363V289-V365 HydrophobicContact CG1-CG1 3.88Å; V289-V365 HydrophobicContact CG1-CG2 4.35Å; V289-V365 HydrophobicContact CG2-CG1 4.07Å; A317-V365 HydrophobicContact CB-CG1 4.47Å; A317-V365 HydrophobicContact CB-CG2 4.13Å; V363-V365 HydrophobicContact CG1-CG2 4.45Å
366K88.9Confident85.6Confident89 Ų8980.5 Ų80.539%0.38740%0.401SS..EExtended strand (participates in β ladder)trans-85.1132.4177.9-66.1-166.9-179.1-168.70110.5A317 V318 S319 L354 V364 L371A317-K366 PolarHBondContact O-N 3.05Å; V318-K366 CarbonylContact C-O 2.98Å; V318-K366 VanDerWaalsContact CA-O 3.26Å; V318-K366 WeakPolarHBondContact CA-O 3.18Å; S319-K366 PolarHBondContact N-O 2.97Å; L354-K366 HydrophobicContact CD2-CD 3.63Å; V364-K366 PolarHBondContact O-N 3.19Å; V364-K366 VanDerWaalsContact O-N 3.09Å; K366-L371 HydrophobicContact CB-CD2 4.34Å; K366-L371 HydrophobicContact CD-CD2 4.12Å
367K90.5Very high85.8Confident152 Ų15283.6 Ų83.666%0.66141%0.409SS*.EExtended strand (participates in β ladder)trans-67.7137.7173.1-65.7-173.7178-175.30110.1D369 S370K367-D369 PolarHBondContact O-N 3.25Å; K367-S370 WeakPolarHBondContact O-CB 3.44Å; K367-S370 PolarHBondContact O-N 3.3Å; K367-S370 PolarHBondContact O-OG 3.29Å
368V89.3Confident86.1Confident0 Ų082.9 Ų82.90%041%0.41CS..G310 helixtrans-55.7-36.9178.8680000111.9V318 S319 M339 F347 F349 S370 L371 H373V318-V368 HydrophobicContact CG1-CB 4.1Å; V318-V368 HydrophobicContact CG1-CG2 4.49Å; S319-V368 WeakPolarHBondContact O-CB 3.5Å; S319-V368 PolarHBondContact O-N 3Å; M339-V368 HydrophobicContact CE-CG2 4.43Å; F347-V368 HydrophobicContact CB-CG2 4.24Å; F347-V368 HydrophobicContact CD1-CG1 4.04Å; F347-V368 HydrophobicContact CD1-CG2 3.66Å; F347-V368 HydrophobicContact CE1-CG1 4.13Å; F347-V368 HydrophobicContact CE1-CG2 4.49Å; F347-V368 HydrophobicContact CG-CG2 4.13Å; F349-V368 HydrophobicContact CD1-CG2 3.94Å; F349-V368 HydrophobicContact CE1-CG2 4.06Å; V368-S370 PolarHBondContact O-N 2.87Å; V368-L371 WeakPolarHBondContact O-CB 3.21Å; V368-L371 PolarHBondContact O-N 2.77Å; V368-H373 HydrophobicContact CG2-CB 4.23Å; V368-H373 PolarHBondContact O-ND1 3.09Å; V368-H373 VanDerWaalsContact O-ND1 3.08Å
369D86.8Confident86.6Confident96 Ų9678 Ų7851%0.51339%0.387SS..G310 helixtrans-64.9-19.9177.8-61.9-65.6000113.8K367 L371 H373 K375K367-D369 PolarHBondContact O-N 3.25Å; D369-L371 VanDerWaalsContact C-N 3.29Å; D369-H373 IonicContact OD1-CE1 3.98Å; D369-H373 IonicContact OD1-NE2 2.96Å; D369-K375 IonicContact OD1-NZ 3.95Å; D369-K375 PolarHBondContact OD1-NZ 2.02Å
370S88.4Confident87.5Confident83 Ų8378.5 Ų78.558%0.5839%0.394SS*.G310 helixtrans-81.7-7.6173.872.90000113.5K367 V368K367-S370 WeakPolarHBondContact O-CB 3.44Å; K367-S370 PolarHBondContact O-N 3.3Å; K367-S370 PolarHBondContact O-OG 3.29Å; V368-S370 PolarHBondContact O-N 2.87Å
371L87.8Confident88.2Confident27 Ų2771.6 Ų71.614%0.14137%0.367CS..SBendtrans-97156.8178.8-50.8-175.4000110.3V318 F349 L354 K366 V368 D369 H373V318-L371 HydrophobicContact CB-CD1 4.48Å; V318-L371 HydrophobicContact CG1-CD1 3.68Å; V318-L371 HydrophobicContact CG2-CD1 3.89Å; F349-L371 HydrophobicContact CD2-CD1 4.05Å; F349-L371 HydrophobicContact CE2-CD1 4.48Å; F349-L371 HydrophobicContact CG-CD1 4.44Å; L354-L371 HydrophobicContact CD1-CD1 4.25Å; L354-L371 HydrophobicContact CD2-CD2 3.62Å; K366-L371 HydrophobicContact CB-CD2 4.34Å; K366-L371 HydrophobicContact CD-CD2 4.12Å; V368-L371 WeakPolarHBondContact O-CB 3.21Å; V368-L371 PolarHBondContact O-N 2.77Å; D369-L371 VanDerWaalsContact C-N 3.29Å; L371-H373 VanDerWaalsContact C-N 3.35Å; L371-H373 PolarHBondContact O-N 3.42Å; L371-H373 PolarHBondContact O-ND1 2.81Å
372N88Confident88.7Confident129 Ų12970.1 Ų70.169%0.6936%0.36SS*.  trans-71.394.8163.7-17213.1000108.7
373H91.1Very high89.2Confident18 Ų1861.8 Ų61.88%0.08332%0.321CS..EExtended strand (participates in β ladder)trans-121.9155.1-175.267.7-80.9000110.8F347 V348 F349 V368 D369 L371 K375F347-H373 AromaticContact CD1-CD2 3.77Å; F347-H373 AromaticContact CE1-CD2 3.95Å; V348-H373 CarbonylContact O-C 3.52Å; V348-H373 WeakPolarHBondContact O-CA 3.26Å; F349-H373 HydrophobicContact CB-CB 3.98Å; V368-H373 HydrophobicContact CG2-CB 4.23Å; V368-H373 PolarHBondContact O-ND1 3.09Å; V368-H373 VanDerWaalsContact O-ND1 3.08Å; D369-H373 IonicContact OD1-CE1 3.98Å; D369-H373 IonicContact OD1-NE2 2.96Å; L371-H373 VanDerWaalsContact C-N 3.35Å; L371-H373 PolarHBondContact O-N 3.42Å; L371-H373 PolarHBondContact O-ND1 2.81Å; H373-K375 WeakPolarHBondContact NE2-CE 3.16Å
374L93.4Very high89.8Confident36 Ų3662 Ų6219%0.18832%0.317CS..EExtended strand (participates in β ladder)trans-104.1129.7168.6-59.1175.8000108.9F347 V348 L376 V410 T413 S418F347-L374 WeakPolarHBondContact CA-O 3.44Å; V348-L374 HydrophobicContact CB-CB 4.28Å; V348-L374 PolarHBondContact N-O 2.96Å; V348-L374 PolarHBondContact O-N 2.95Å; L374-L376 HydrophobicContact CB-CD2 4.21Å; L374-V410 HydrophobicContact CD1-CB 4.09Å; L374-T413 HydrophobicContact CD2-CG2 4.12Å; L374-S418 CarbonylContact C-O 3.53Å; L374-S418 WeakPolarHBondContact CA-O 3.33Å
375K93.2Very high90.4Very high56 Ų5657.3 Ų57.324%0.24329%0.289CS..EExtended strand (participates in β ladder)trans-93.9111.3167.8-56.7-166.9-174.5-162.80108F347 D369 H373 S418 V419 C420F347-K375 HydrophobicContact CD1-CG 4.35Å; F347-K375 HydrophobicContact CE1-CD 3.99Å; F347-K375 HydrophobicContact CE1-CG 3.75Å; F347-K375 HydrophobicContact CZ-CD 4.24Å; F347-K375 HydrophobicContact CZ-CG 4.23Å; D369-K375 IonicContact OD1-NZ 3.95Å; D369-K375 PolarHBondContact OD1-NZ 2.02Å; H373-K375 WeakPolarHBondContact NE2-CE 3.16Å; K375-S418 PolarHBondContact N-O 3.16Å; K375-V419 WeakPolarHBondContact O-CA 3.1Å; K375-C420 PolarHBondContact O-N 2.87Å
376L95.6Very high91Very high1 Ų154.4 Ų54.41%0.00527%0.271CS..EExtended strand (participates in β ladder)trans-87.5119.9175.2-44.2-175000108.4E345 V346 V348 L374 L396 W408 V410 C420E345-L376 WeakPolarHBondContact CA-O 2.9Å; V346-L376 HydrophobicContact CB-CB 4.1Å; V346-L376 HydrophobicContact CB-CD1 4.15Å; V346-L376 HydrophobicContact CB-CG 4.3Å; V346-L376 HydrophobicContact CG1-CD1 4.1Å; V346-L376 PolarHBondContact N-O 3.16Å; V346-L376 PolarHBondContact O-N 3.11Å; V348-L376 HydrophobicContact CG2-CD1 3.7Å; V348-L376 HydrophobicContact CG2-CD2 4.34Å; V348-L376 HydrophobicContact CG2-CG 4.06Å; L374-L376 HydrophobicContact CB-CD2 4.21Å; L376-L396 HydrophobicContact CD1-CD2 3.53Å; L376-W408 HydrophobicContact CB-CD2 3.97Å; L376-W408 HydrophobicContact CB-CG 4.13Å; L376-W408 HydrophobicContact CB-CZ2 4.01Å; L376-W408 HydrophobicContact CD1-CB 4.18Å; L376-W408 HydrophobicContact CD1-CD2 3.87Å; L376-W408 HydrophobicContact CD1-CE3 4.06Å; L376-W408 HydrophobicContact CD1-CG 3.94Å; L376-W408 HydrophobicContact CD2-CG 4.48Å; L376-W408 HydrophobicContact CG-CG 4.42Å; L376-V410 HydrophobicContact CD1-CG1 4.13Å; L376-V410 HydrophobicContact CD2-CG1 3.96Å; L376-C420 WeakPolarHBondContact CA-O 3.29Å; L376-C420 HydrophobicContact CD2-CB 3.46Å; L376-C420 VanDerWaalsContact CD2-CB 3.46Å
377K93.7Very high91.4Very high109 Ų10951.2 Ų51.247%0.47426%0.26SS..  trans-103.3146.1178.5-67.2-168.8175.2-166.50110.1E345 W408 V419 C420 T422E345-K377 HydrophobicContact CG-CG 4.3Å; K377-W408 PolarHBondContact O-NE1 2.65Å; K377-V419 HydrophobicContact CD-CG1 3.82Å; K377-V419 HydrophobicContact CG-CG1 3.95Å; K377-C420 PolarHBondContact N-O 3.18Å; K377-T422 WeakPolarHBondContact O-CG2 3.27Å
378G91.6Very high91.8Very high13 Ų1344.5 Ų44.513%0.13423%0.23CC..  trans163.8-36.3179.100000112
379H94.6Very high92.2Very high12 Ų1244.6 Ų44.66%0.05623%0.231CC..  trans-88.2159.8176.1-66.4-57.6000113.4P344 S398 S400 D402 V404 C406 W408P344-H379 VanDerWaalsContact CB-O 3.27Å; P344-H379 WeakPolarHBondContact CB-O 3.39Å; P344-H379 WeakPolarHBondContact O-CB 3.35Å; H379-S398 PolarHBondContact CD2-OG 2.05Å; H379-S398 PolarHBondContact NE2-O 2.98Å; H379-S398 PolarHBondContact NE2-OG 3.26Å; H379-S400 VanDerWaalsContact CE1-CB 3.48Å; H379-S400 WeakPolarHBondContact CE1-CB 3.46Å; H379-S400 WeakPolarHBondContact ND1-CB 3.48Å; H379-D402 VanDerWaalsContact CA-OD2 3.3Å; H379-D402 WeakPolarHBondContact CA-OD2 3.23Å; H379-D402 VanDerWaalsContact CB-OD2 3.23Å; H379-D402 WeakPolarHBondContact CB-OD2 3.49Å; H379-D402 IonicContact CG-OD2 2.86Å; H379-D402 IonicContact ND1-OD1 2.74Å; H379-D402 PolarHBondContact ND1-OD1 3.36Å; H379-D402 IonicContact ND1-OD2 2.77Å; H379-D402 PolarHBondContact ND1-OD2 3.5Å; H379-V404 PolarHBondContact CE1-O 3.38Å; H379-C406 PolarHBondContact CE1-SG 3.06Å; H379-W408 AromaticContact CD2-CH2 3.79Å; H379-W408 AromaticContact NE2-CH2 3.71Å
380F90.1Very high92.5Very high169 Ų16943.3 Ų43.374%0.74122%0.222SC*.SBendtrans-117.1-7.9174.5-55.7-80.9000112.7D402F380-D402 HydrophobicContact CB-CB 4.4Å; F380-D402 PolarHBondContact N-OD2 3.16Å
381S88.6Confident92.8Very high40 Ų4045.9 Ų45.928%0.2822%0.219SC..SBendtrans-136.3174.5178.9-161.20000113K340 P344 S400 D402K340-S381 PolarHBondContact NZ-O 3.39Å; K340-S381 VanDerWaalsContact NZ-O 3.11Å; P344-S381 WeakPolarHBondContact CA-O 3.38Å; S381-S400 PolarHBondContact O-OG 3.12Å; S381-D402 PolarHBondContact N-OD2 3.15Å; S381-D402 VanDerWaalsContact N-OD2 3.09Å
382E85.7Confident93.2Very high40 Ų4048.9 Ų48.919%0.18723%0.228CC..  trans-71.2172.9170.871.1175164.600112.2Q342 S400 R401Q342-E382 WeakPolarHBondContact CG-OE2 3.36Å; E382-S400 PolarHBondContact O-OG 3.48Å; E382-R401 HydrophobicContact CG-CG 4.47Å; E382-R401 PolarHBondContact O-N 3.27Å; E382-R401 IonicContact OE1-CZ 3.39Å; E382-R401 IonicContact OE1-NE 2.95Å; E382-R401 IonicContact OE1-NH1 3.59Å; E382-R401 PolarHBondContact OE1-NH1 3.12Å
383G87.6Confident93.6Very high1 Ų145.5 Ų45.51%0.0121%0.212CC..  trans177.8167.6176.700000113.4T325 K340T325-G383 WeakPolarHBondContact CB-O 3.35Å; T325-G383 PolarHBondContact OG1-O 2.79Å; K340-G383 VanDerWaalsContact CE-CA 3.46Å; K340-G383 VanDerWaalsContact CE-N 3.29Å; K340-G383 WeakPolarHBondContact CG-O 3.37Å
384F92.9Very high93.8Very high68 Ų6844.7 Ų44.730%0.29821%0.208SC..SBendtrans-108.7-25.2-172.5-64-91.3000112.9T325 R326 L386T325-F384 HydrophobicContact CG2-CD1 4.45Å; T325-F384 HydrophobicContact CG2-CE1 4.04Å; T325-F384 HydrophobicContact CG2-CZ 4.22Å; R326-F384 VanDerWaalsContact CB-O 3.28Å; R326-F384 WeakPolarHBondContact CB-O 3.17Å; R326-F384 VanDerWaalsContact CD-O 3.31Å; R326-F384 WeakPolarHBondContact CD-O 3.4Å; R326-F384 WeakPolarHBondContact CG-O 3.34Å; F384-L386 PolarHBondContact O-N 2.97Å
385G95.6Very high94Very high0 Ų044.8 Ų44.80%021%0.207CC..  trans-67120176.800000112.8S398 G399 N434G385-S398 WeakPolarHBondContact O-CA 3.4Å; G385-S398 WeakPolarHBondContact O-CB 3.39Å; G385-G399 PolarHBondContact O-N 2.91Å; G385-N434 PolarHBondContact N-O 3.08Å
386L97.9Very high94.2Very high4 Ų442.1 Ų42.12%0.02120%0.195CC..EExtended strand (participates in β ladder)trans-154.2116.8174.5-169.469000110.1R326 R328 A338 K340 V346 F384 L396 L397R326-L386 HydrophobicContact CB-CB 4.02Å; R326-L386 HydrophobicContact CB-CD2 4.33Å; R326-L386 HydrophobicContact CG-CB 3.73Å; R326-L386 HydrophobicContact CG-CD2 4.45Å; R328-L386 HydrophobicContact CB-CD2 4.44Å; R328-L386 HydrophobicContact CG-CD2 4.46Å; A338-L386 HydrophobicContact CB-CD1 4.32Å; A338-L386 HydrophobicContact CB-CD2 3.95Å; A338-L386 HydrophobicContact CB-CG 4.41Å; K340-L386 HydrophobicContact CB-CD2 4.4Å; V346-L386 HydrophobicContact CG1-CD1 3.96Å; V346-L386 HydrophobicContact CG2-CD1 4.47Å; F384-L386 PolarHBondContact O-N 2.97Å; L386-L396 HydrophobicContact CD1-CD1 3.83Å; L386-L396 HydrophobicContact CD1-CD2 4.11Å; L386-L396 HydrophobicContact CD1-CG 4.17Å; L386-L396 HydrophobicContact CG-CD1 4.2Å; L386-L397 WeakPolarHBondContact CA-O 3.48Å
387S98Very high94.3Very high21 Ų2142.1 Ų42.115%0.14720%0.195CC..EExtended strand (participates in β ladder)trans-142.3119.6-174.2-166.50000112.5L397 V436 W438S387-L397 PolarHBondContact N-O 3.41Å; S387-L397 PolarHBondContact O-N 2.9Å; S387-V436 WeakPolarHBondContact CB-O 3.3Å; S387-W438 PolarHBondContact O-NE1 3.48Å; S387-W438 VanDerWaalsContact O-NE1 3.1Å; S387-W438 PolarHBondContact OG-N 3.47Å
388W98.3Very high94.5Very high11 Ų1136.9 Ų36.94%0.04217%0.172CC..EExtended strand (participates in β ladder)trans-79.7144.1171.1-74.5103.5000110.6R328 M330 P331 A338 V348 E390 L396 V410R328-W388 PolarHBondContact O-NE1 2.75Å; M330-W388 HydrophobicContact CB-CD2 3.98Å; M330-W388 HydrophobicContact CB-CE3 4.26Å; M330-W388 HydrophobicContact CB-CG 4.42Å; M330-W388 HydrophobicContact CB-CZ2 4.25Å; M330-W388 HydrophobicContact CE-CE3 3.98Å; M330-W388 HydrophobicContact CE-CH2 3.47Å; M330-W388 VanDerWaalsContact CE-CH2 3.47Å; M330-W388 HydrophobicContact CE-CZ2 4.17Å; M330-W388 HydrophobicContact CE-CZ3 3.37Å; M330-W388 HydrophobicContact CG-CD2 4.3Å; M330-W388 HydrophobicContact CG-CE3 4.14Å; M330-W388 HydrophobicContact CG-CZ3 4.46Å; P331-W388 HydrophobicContact CG-CB 4.31Å; A338-W388 HydrophobicContact CB-CZ2 3.52Å; V348-W388 HydrophobicContact CG1-CH2 4.07Å; V348-W388 HydrophobicContact CG1-CZ2 4.19Å; V348-W388 HydrophobicContact CG2-CH2 4.23Å; V348-W388 HydrophobicContact CG2-CZ2 4.29Å; W388-E390 PolarHBondContact O-N 2.88Å; W388-L396 HydrophobicContact CD2-CB 4.37Å; W388-L396 HydrophobicContact CD2-CD1 3.65Å; W388-L396 HydrophobicContact CE3-CB 3.83Å; W388-L396 HydrophobicContact CE3-CD1 4.01Å; W388-L396 HydrophobicContact CE3-CG 4.43Å; W388-L396 HydrophobicContact CG-CD1 3.89Å; W388-L396 HydrophobicContact CH2-CB 4.23Å; W388-L396 HydrophobicContact CH2-CD2 4.18Å; W388-L396 HydrophobicContact CZ2-CD1 4.31Å; W388-L396 HydrophobicContact CZ2-CD2 4.24Å; W388-L396 HydrophobicContact CZ3-CB 3.72Å; W388-L396 HydrophobicContact CZ3-CD1 4.42Å; W388-L396 HydrophobicContact CZ3-CD2 4.49Å; W388-L396 HydrophobicContact CZ3-CG 4.44Å; W388-V410 HydrophobicContact CH2-CG1 4.22Å; W388-V410 HydrophobicContact CH2-CG2 4.04Å; W388-V410 HydrophobicContact CZ3-CG1 4.43Å; W388-V410 HydrophobicContact CZ3-CG2 4.1Å
389N97.6Very high94.8Very high2 Ų236.3 Ų36.31%0.01117%0.166CC..  trans-71.1127.8172.6-166.6-63000110.5Q332 R391 R392 Y395 W438 P443Q332-N389 PolarHBondContact NE2-O 3.48Å; N389-R391 VanDerWaalsContact C-N 3.33Å; N389-R391 PolarHBondContact O-N 3.12Å; N389-R391 PolarHBondContact OD1-N 3.29Å; N389-R392 HydrophobicContact CB-CB 4.27Å; N389-R392 PolarHBondContact OD1-N 2.71Å; N389-Y395 PolarHBondContact N-O 2.75Å; N389-W438 HydrophobicContact CB-CD2 4.07Å; N389-W438 HydrophobicContact CB-CG 4.21Å; N389-W438 HydrophobicContact CB-CZ2 4.33Å; N389-W438 VanDerWaalsContact ND2-CE3 3.27Å; N389-W438 WeakPolarHBondContact ND2-CZ3 3.33Å; N389-P443 PolarHBondContact ND2-O 2.87Å
390E93.9Very high94.7Very high70 Ų7035.7 Ų35.733%0.32716%0.163SC..SBendtrans-70.7-23.7-176-71.9-75.8176.800113.3P331 Q332 W388 K586P331-E390 VanDerWaalsContact CB-OE2 3.29Å; P331-E390 WeakPolarHBondContact CB-OE2 3.15Å; P331-E390 HydrophobicContact CG-CG 4.46Å; P331-E390 VanDerWaalsContact CG-OE2 3.3Å; P331-E390 WeakPolarHBondContact CG-OE2 3.44Å; Q332-E390 PolarHBondContact NE2-O 3.48Å; W388-E390 PolarHBondContact O-N 2.88Å; E390-K586 IonicContact OE1-NZ 2.74Å; E390-K586 PolarHBondContact OE1-NZ 3.06Å; E390-K586 IonicContact OE2-NZ 2.81Å
391R94.5Very high94.8Very high137 Ų13734 Ų3452%0.51715%0.152SC..SBendtrans-114.7-38.7-178.5-57.8-175.6177.8-164-6114.3N389 T393 S440 M441 P443N389-R391 VanDerWaalsContact C-N 3.33Å; N389-R391 PolarHBondContact O-N 3.12Å; N389-R391 PolarHBondContact OD1-N 3.29Å; R391-T393 PolarHBondContact O-N 3.4Å; R391-S440 PolarHBondContact NE-O 2.99Å; R391-M441 PolarHBondContact NH1-O 3.39Å; R391-M441 PolarHBondContact NH2-SD 3.12Å; R391-P443 HydrophobicContact CB-CB 4.04Å; R391-P443 HydrophobicContact CB-CG 4.44Å
392R95.2Very high94.8Very high90 Ų9034.1 Ų34.134%0.3415%0.15SC..SBendtrans-87.2109.5178.5-72179.6174.1-161.5-0.3110N389 G394 Y395 P443N389-R392 HydrophobicContact CB-CB 4.27Å; N389-R392 PolarHBondContact OD1-N 2.71Å; R392-G394 PolarHBondContact O-N 3.45Å; R392-Y395 HydrophobicContact CB-CD2 3.9Å; R392-Y395 HydrophobicContact CB-CE2 4.48Å; R392-Y395 HydrophobicContact CB-CG 4.04Å; R392-Y395 PolarHBondContact O-N 2.83Å; R392-P443 HydrophobicContact CG-CB 4.05Å
393T95.8Very high95.1Very high58 Ų5832.3 Ų32.336%0.35614%0.141SC..THydrogen-bonded Turntrans-62.4133-179.3-56.70000110.8M330 Q332 R391 Y395 N411M330-T393 HydrophobicContact SD-CG2 3.84Å; Q332-T393 HydrophobicContact CB-CG2 4.23Å; Q332-T393 WeakPolarHBondContact CG-OG1 3.43Å; R391-T393 PolarHBondContact O-N 3.4Å; T393-Y395 VanDerWaalsContact C-N 3.33Å; T393-Y395 PolarHBondContact O-N 2.97Å; T393-N411 PolarHBondContact O-ND2 2.85Å
394G95.3Very high95.4Very high0 Ų032.7 Ų32.70%014%0.143CC..THydrogen-bonded Turntrans83.9-3.1174.500000116.3R392 D409 V410R392-G394 PolarHBondContact O-N 3.45Å; G394-D409 WeakPolarHBondContact O-CA 3.37Å; G394-V410 WeakPolarHBondContact O-CG2 3.04Å; G394-V410 PolarHBondContact O-N 2.92Å
395Y97.5Very high95.6Very high39 Ų3929.4 Ų29.415%0.15313%0.129CC..EExtended strand (participates in β ladder)trans-85.9123177.3-80.2-117.8000110.1N389 R392 T393 L407 W408 D409 I423 I460N389-Y395 PolarHBondContact N-O 2.75Å; R392-Y395 HydrophobicContact CB-CD2 3.9Å; R392-Y395 HydrophobicContact CB-CE2 4.48Å; R392-Y395 HydrophobicContact CB-CG 4.04Å; R392-Y395 PolarHBondContact O-N 2.83Å; T393-Y395 VanDerWaalsContact C-N 3.33Å; T393-Y395 PolarHBondContact O-N 2.97Å; Y395-L407 HydrophobicContact CD1-CD1 4.11Å; Y395-W408 WeakPolarHBondContact CA-O 3.32Å; Y395-D409 HydrophobicContact CD2-CB 4.45Å; Y395-D409 HydrophobicContact CE2-CB 4.14Å; Y395-I423 HydrophobicContact CE1-CD1 4.29Å; Y395-I460 HydrophobicContact CE1-CD1 4.37Å
396L98.2Very high95.6Very high0 Ų029.4 Ų29.40%013%0.129CC..EExtended strand (participates in β ladder)trans-129.7134.2-177.1-179.165.9000110.3A338 V346 V348 L376 L386 W388 L407 W408A338-L396 HydrophobicContact CB-CD1 4.09Å; A338-L396 HydrophobicContact CB-CD2 3.65Å; V346-L396 HydrophobicContact CG1-CD2 4.09Å; V348-L396 HydrophobicContact CG2-CD2 4.18Å; L376-L396 HydrophobicContact CD1-CD2 3.53Å; L386-L396 HydrophobicContact CD1-CD1 3.83Å; L386-L396 HydrophobicContact CD1-CD2 4.11Å; L386-L396 HydrophobicContact CD1-CG 4.17Å; L386-L396 HydrophobicContact CG-CD1 4.2Å; W388-L396 HydrophobicContact CD2-CB 4.37Å; W388-L396 HydrophobicContact CD2-CD1 3.65Å; W388-L396 HydrophobicContact CE3-CB 3.83Å; W388-L396 HydrophobicContact CE3-CD1 4.01Å; W388-L396 HydrophobicContact CE3-CG 4.43Å; W388-L396 HydrophobicContact CG-CD1 3.89Å; W388-L396 HydrophobicContact CH2-CB 4.23Å; W388-L396 HydrophobicContact CH2-CD2 4.18Å; W388-L396 HydrophobicContact CZ2-CD1 4.31Å; W388-L396 HydrophobicContact CZ2-CD2 4.24Å; W388-L396 HydrophobicContact CZ3-CB 3.72Å; W388-L396 HydrophobicContact CZ3-CD1 4.42Å; W388-L396 HydrophobicContact CZ3-CD2 4.49Å; W388-L396 HydrophobicContact CZ3-CG 4.44Å; L396-L407 WeakPolarHBondContact O-CA 3.11Å; L396-W408 PolarHBondContact N-O 2.86Å; L396-W408 PolarHBondContact O-N 3.3Å
397L98Very high95.5Very high0 Ų029.4 Ų29.40%013%0.129CC..EExtended strand (participates in β ladder)trans-105.7146.8168.4-70.7169.4000110.4L386 S387 V405 C406 L407 V436 W438 F446L386-L397 WeakPolarHBondContact CA-O 3.48Å; S387-L397 PolarHBondContact N-O 3.41Å; S387-L397 PolarHBondContact O-N 2.9Å; L397-V405 HydrophobicContact CD2-CG1 4.26Å; L397-C406 WeakPolarHBondContact CA-O 3.46Å; L397-L407 HydrophobicContact CD2-CB 3.99Å; L397-L407 HydrophobicContact CD2-CD1 3.93Å; L397-L407 HydrophobicContact CG-CD1 4.44Å; L397-V436 HydrophobicContact CB-CG2 3.95Å; L397-W438 HydrophobicContact CD1-CD2 3.6Å; L397-W438 HydrophobicContact CD1-CE3 4.22Å; L397-W438 HydrophobicContact CD1-CG 3.95Å; L397-W438 HydrophobicContact CD1-CH2 4.18Å; L397-W438 HydrophobicContact CD1-CZ2 3.6Å; L397-W438 HydrophobicContact CD1-CZ3 4.47Å; L397-W438 VanDerWaalsContact CD1-NE1 3.34Å; L397-W438 HydrophobicContact CD2-CZ2 4.03Å; L397-W438 HydrophobicContact CG-CD2 4.31Å; L397-W438 VanDerWaalsContact CG-CE2 3.43Å; L397-W438 HydrophobicContact CG-CH2 4.34Å; L397-W438 HydrophobicContact CG-CZ2 3.48Å; L397-W438 VanDerWaalsContact CG-CZ2 3.48Å; L397-F446 HydrophobicContact CD1-CB 3.4Å; L397-F446 VanDerWaalsContact CD1-CB 3.4Å; L397-F446 HydrophobicContact CD1-CD1 3.93Å; L397-F446 HydrophobicContact CD1-CD2 3.67Å; L397-F446 HydrophobicContact CD1-CE2 4.38Å; L397-F446 HydrophobicContact CD1-CG 3.39Å; L397-F446 HydrophobicContact CD2-CD1 4.39Å; L397-F446 HydrophobicContact CD2-CD2 4.41Å; L397-F446 HydrophobicContact CD2-CE1 4.31Å; L397-F446 HydrophobicContact CD2-CE2 4.32Å; L397-F446 HydrophobicContact CD2-CG 4.43Å; L397-F446 HydrophobicContact CD2-CZ 4.26Å
398S98.2Very high95.5Very high0 Ų028.4 Ų28.40%012%0.122CC..EExtended strand (participates in β ladder)trans-140.8151.5158600000112.3H379 G385 V405 C406 W408H379-S398 PolarHBondContact CD2-OG 2.05Å; H379-S398 PolarHBondContact NE2-O 2.98Å; H379-S398 PolarHBondContact NE2-OG 3.26Å; G385-S398 WeakPolarHBondContact O-CA 3.4Å; G385-S398 WeakPolarHBondContact O-CB 3.39Å; S398-V405 WeakPolarHBondContact O-CA 2.96Å; S398-C406 PolarHBondContact N-O 3.14Å; S398-C406 VanDerWaalsContact N-O 3.08Å; S398-C406 PolarHBondContact O-N 3.11Å; S398-W408 WeakPolarHBondContact OG-CH2 3.35Å; S398-W408 WeakPolarHBondContact OG-CZ3 3.28Å
399G96.6Very high95.3Very high0 Ų028.6 Ų28.60%012%0.124CC..EExtended strand (participates in β ladder)trans-112.5154.317000000110K340 G385K340-G399 WeakPolarHBondContact CE-O 3.24Å; G385-G399 PolarHBondContact O-N 2.91Å
400S93.8Very high95.1Very high0 Ų029.2 Ų29.20%013%0.127CC..  trans-146.7158.4-171.7174.40000111.8H379 S381 E382 D402 G403 V404 V433H379-S400 VanDerWaalsContact CE1-CB 3.48Å; H379-S400 WeakPolarHBondContact CE1-CB 3.46Å; H379-S400 WeakPolarHBondContact ND1-CB 3.48Å; S381-S400 PolarHBondContact O-OG 3.12Å; E382-S400 PolarHBondContact O-OG 3.48Å; S400-D402 WeakPolarHBondContact CB-OD1 3.35Å; S400-D402 PolarHBondContact O-N 2.95Å; S400-D402 VanDerWaalsContact O-N 3.16Å; S400-D402 PolarHBondContact OG-N 3Å; S400-D402 PolarHBondContact OG-OD1 2.8Å; S400-D402 VanDerWaalsContact OG-OD1 3.09Å; S400-D402 PolarHBondContact OG-OD2 3.32Å; S400-G403 PolarHBondContact O-N 3.09Å; S400-V404 PolarHBondContact N-O 2.9Å; S400-V433 PolarHBondContact O-N 3.36Å
401R90.8Very high94.9Very high133 Ų13330.4 Ų30.450%0.50214%0.136SC..THydrogen-bonded Turntrans-65-13.1176.3-73.6-172.1168.9-163-5.9113.8E382 G403 P432E382-R401 HydrophobicContact CG-CG 4.47Å; E382-R401 PolarHBondContact O-N 3.27Å; E382-R401 IonicContact OE1-CZ 3.39Å; E382-R401 IonicContact OE1-NE 2.95Å; E382-R401 IonicContact OE1-NH1 3.59Å; E382-R401 PolarHBondContact OE1-NH1 3.12Å; R401-G403 PolarHBondContact O-N 2.96Å; R401-P432 HydrophobicContact CB-CB 4.46Å; R401-P432 HydrophobicContact CG-CB 4.46Å
402D89.9Confident94.3Very high43 Ų4332 Ų3223%0.2314%0.142CC..THydrogen-bonded Turntrans-75.1-1.7171.55529.6000113.6H379 F380 S381 S400 V404H379-D402 VanDerWaalsContact CA-OD2 3.3Å; H379-D402 WeakPolarHBondContact CA-OD2 3.23Å; H379-D402 VanDerWaalsContact CB-OD2 3.23Å; H379-D402 WeakPolarHBondContact CB-OD2 3.49Å; H379-D402 IonicContact CG-OD2 2.86Å; H379-D402 IonicContact ND1-OD1 2.74Å; H379-D402 PolarHBondContact ND1-OD1 3.36Å; H379-D402 IonicContact ND1-OD2 2.77Å; H379-D402 PolarHBondContact ND1-OD2 3.5Å; F380-D402 HydrophobicContact CB-CB 4.4Å; F380-D402 PolarHBondContact N-OD2 3.16Å; S381-D402 PolarHBondContact N-OD2 3.15Å; S381-D402 VanDerWaalsContact N-OD2 3.09Å; S400-D402 WeakPolarHBondContact CB-OD1 3.35Å; S400-D402 PolarHBondContact O-N 2.95Å; S400-D402 VanDerWaalsContact O-N 3.16Å; S400-D402 PolarHBondContact OG-N 3Å; S400-D402 PolarHBondContact OG-OD1 2.8Å; S400-D402 VanDerWaalsContact OG-OD1 3.09Å; S400-D402 PolarHBondContact OG-OD2 3.32Å; D402-V404 VanDerWaalsContact C-N 3.28Å; D402-V404 HydrophobicContact CB-CG2 4.42Å; D402-V404 PolarHBondContact O-N 3.19Å; D402-V404 VanDerWaalsContact OD1-CB 3.24Å; D402-V404 WeakPolarHBondContact OD1-CB 3.16Å; D402-V404 WeakPolarHBondContact OD1-CG2 3.48Å; D402-V404 PolarHBondContact OD1-N 2.79Å
403G91.6Very high93.4Very high1 Ų128.9 Ų28.91%0.0113%0.133CC..SBendtrans79.28.3-178.100000113.7S400 R401 E428 A431S400-G403 PolarHBondContact O-N 3.09Å; R401-G403 PolarHBondContact O-N 2.96Å; G403-E428 WeakPolarHBondContact O-CB 3.47Å; G403-E428 PolarHBondContact O-N 3.18Å; G403-A431 WeakPolarHBondContact CA-O 3.23Å
404V94.5Very high91.8Very high9 Ų928.9 Ų28.96%0.05514%0.139CC..EExtended strand (participates in β ladder)trans-98.3139.2-178.9-171.50000110.1H379 S400 D402 E425 W426 I427H379-V404 PolarHBondContact CE1-O 3.38Å; S400-V404 PolarHBondContact N-O 2.9Å; D402-V404 VanDerWaalsContact C-N 3.28Å; D402-V404 HydrophobicContact CB-CG2 4.42Å; D402-V404 PolarHBondContact O-N 3.19Å; D402-V404 VanDerWaalsContact OD1-CB 3.24Å; D402-V404 WeakPolarHBondContact OD1-CB 3.16Å; D402-V404 WeakPolarHBondContact OD1-CG2 3.48Å; D402-V404 PolarHBondContact OD1-N 2.79Å; V404-E425 HydrophobicContact CG1-CB 4.25Å; V404-E425 HydrophobicContact CG1-CG 4.45Å; V404-W426 CarbonylContact C-O 3.58Å; V404-W426 WeakPolarHBondContact CA-O 3.19Å; V404-I427 HydrophobicContact CG2-CG1 4.37Å
405V96Very high90.3Very high0 Ų041 Ų410%019%0.185CC..EExtended strand (participates in β ladder)trans-105.6124161.5-176.50000108.5L397 S398 E425 W426 V433 V436 F446 Y448L397-V405 HydrophobicContact CD2-CG1 4.26Å; S398-V405 WeakPolarHBondContact O-CA 2.96Å; V405-E425 WeakPolarHBondContact O-CA 3.49Å; V405-W426 HydrophobicContact CB-CB 4.28Å; V405-W426 HydrophobicContact CB-CE3 4.37Å; V405-W426 HydrophobicContact CG1-CE3 4.3Å; V405-W426 PolarHBondContact N-O 2.92Å; V405-W426 PolarHBondContact O-N 3.41Å; V405-V433 HydrophobicContact CG2-CG1 4.04Å; V405-V433 HydrophobicContact CG2-CG2 3.96Å; V405-V436 HydrophobicContact CG1-CG1 4.31Å; V405-V436 HydrophobicContact CG2-CG1 4.47Å; V405-F446 HydrophobicContact CG1-CE2 3.93Å; V405-F446 HydrophobicContact CG1-CZ 4.46Å; V405-Y448 HydrophobicContact CG2-CD1 3.95Å; V405-Y448 HydrophobicContact CG2-CD2 3.86Å; V405-Y448 HydrophobicContact CG2-CE1 4.15Å; V405-Y448 HydrophobicContact CG2-CE2 4.09Å; V405-Y448 HydrophobicContact CG2-CG 3.77Å
406C96.4Very high88.5Confident0 Ų050.7 Ų50.70%022%0.221CC..EExtended strand (participates in β ladder)trans-112.1138.9-178.6-75.50000111.3H379 L397 S398 W408 T422H379-C406 PolarHBondContact CE1-SG 3.06Å; L397-C406 WeakPolarHBondContact CA-O 3.46Å; S398-C406 PolarHBondContact N-O 3.14Å; S398-C406 VanDerWaalsContact N-O 3.08Å; S398-C406 PolarHBondContact O-N 3.11Å; C406-W408 HydrophobicContact CB-CD2 4.39Å; C406-W408 HydrophobicContact CB-CE3 4.09Å; C406-W408 HydrophobicContact CB-CH2 3.02Å; C406-W408 HydrophobicContact CB-CZ2 3.35Å; C406-W408 HydrophobicContact CB-CZ3 3.4Å; C406-W408 VanDerWaalsContact CB-CZ3 3.4Å; C406-W408 WeakPolarHBondContact O-CZ3 3.16Å; C406-T422 HydrophobicContact CB-CG2 3.76Å
407L96.7Very high86.9Confident3 Ų355.5 Ų55.52%0.01625%0.247CC..EExtended strand (participates in β ladder)trans-113.9129.6171.7172.665.4000110.8Y395 L396 L397 T422 I423 S424 W426 W438 I460Y395-L407 HydrophobicContact CD1-CD1 4.11Å; L396-L407 WeakPolarHBondContact O-CA 3.11Å; L397-L407 HydrophobicContact CD2-CB 3.99Å; L397-L407 HydrophobicContact CD2-CD1 3.93Å; L397-L407 HydrophobicContact CG-CD1 4.44Å; L407-T422 CarbonylContact O-C 3.52Å; L407-T422 WeakPolarHBondContact O-CA 3.43Å; L407-I423 HydrophobicContact CD2-CB 4.41Å; L407-I423 HydrophobicContact CG-CB 4.35Å; L407-I423 HydrophobicContact CG-CD1 4.33Å; L407-I423 PolarHBondContact O-N 2.94Å; L407-S424 PolarHBondContact N-O 3.41Å; L407-W426 HydrophobicContact CB-CH2 4.13Å; L407-W426 HydrophobicContact CB-CZ3 3.72Å; L407-W426 HydrophobicContact CD2-CH2 4.06Å; L407-W438 HydrophobicContact CD1-CH2 4.05Å; L407-W438 HydrophobicContact CD1-CZ2 3.66Å; L407-I460 HydrophobicContact CD2-CB 4.37Å; L407-I460 HydrophobicContact CD2-CG2 3.78Å
408W96.2Very high86.3Confident0 Ų058.4 Ų58.40%027%0.267CS..EExtended strand (participates in β ladder)trans-122.6152.3171.6-58.6-93.9000112.4V346 L376 K377 H379 Y395 L396 S398 C406 V410 S421 T422V346-W408 HydrophobicContact CG2-CH2 4.29Å; L376-W408 HydrophobicContact CB-CD2 3.97Å; L376-W408 HydrophobicContact CB-CG 4.13Å; L376-W408 HydrophobicContact CB-CZ2 4.01Å; L376-W408 HydrophobicContact CD1-CB 4.18Å; L376-W408 HydrophobicContact CD1-CD2 3.87Å; L376-W408 HydrophobicContact CD1-CE3 4.06Å; L376-W408 HydrophobicContact CD1-CG 3.94Å; L376-W408 HydrophobicContact CD2-CG 4.48Å; L376-W408 HydrophobicContact CG-CG 4.42Å; K377-W408 PolarHBondContact O-NE1 2.65Å; H379-W408 AromaticContact CD2-CH2 3.79Å; H379-W408 AromaticContact NE2-CH2 3.71Å; Y395-W408 WeakPolarHBondContact CA-O 3.32Å; L396-W408 PolarHBondContact N-O 2.86Å; L396-W408 PolarHBondContact O-N 3.3Å; S398-W408 WeakPolarHBondContact OG-CH2 3.35Å; S398-W408 WeakPolarHBondContact OG-CZ3 3.28Å; C406-W408 HydrophobicContact CB-CD2 4.39Å; C406-W408 HydrophobicContact CB-CE3 4.09Å; C406-W408 HydrophobicContact CB-CH2 3.02Å; C406-W408 HydrophobicContact CB-CZ2 3.35Å; C406-W408 HydrophobicContact CB-CZ3 3.4Å; C406-W408 VanDerWaalsContact CB-CZ3 3.4Å; C406-W408 WeakPolarHBondContact O-CZ3 3.16Å; W408-V410 HydrophobicContact CB-CG1 4.49Å; W408-S421 VanDerWaalsContact CD1-C 3.46Å; W408-S421 VanDerWaalsContact CD1-O 3.25Å; W408-T422 HydrophobicContact CD2-CG2 4.38Å; W408-T422 HydrophobicContact CZ2-CG2 3.89Å
409D95Very high85.8Confident15 Ų1561.3 Ų61.38%0.0829%0.285CS..EExtended strand (participates in β ladder)trans-116.198.6163.3174.3-0.6000107.5G394 Y395 N411 R412 I423G394-D409 WeakPolarHBondContact O-CA 3.37Å; Y395-D409 HydrophobicContact CD2-CB 4.45Å; Y395-D409 HydrophobicContact CE2-CB 4.14Å; D409-N411 PolarHBondContact O-N 3.32Å; D409-N411 VanDerWaalsContact O-N 3.16Å; D409-N411 WeakPolarHBondContact OD1-CB 3.18Å; D409-N411 PolarHBondContact OD1-N 3.21Å; D409-R412 HydrophobicContact CB-CG 4.2Å; D409-R412 PolarHBondContact O-N 2.87Å; D409-R412 VanDerWaalsContact O-N 3.15Å; D409-R412 WeakPolarHBondContact OD2-CD 3.24Å; D409-R412 VanDerWaalsContact OD2-CG 3.28Å; D409-R412 WeakPolarHBondContact OD2-CG 3.38Å; D409-R412 IonicContact OD2-CZ 3.77Å; D409-R412 IonicContact OD2-NE 2.78Å; D409-R412 PolarHBondContact OD2-NE 3.25Å; D409-I423 HydrophobicContact CB-CD1 3.28Å; D409-I423 HydrophobicContact CB-CG1 4.17Å
410V93.2Very high85.5Confident15 Ų1561.8 Ų61.89%0.09129%0.288CS..THydrogen-bonded Turntrans-71.2-8.4-174.8-52.30000112.8M330 V348 L374 L376 W388 G394 W408 T413M330-V410 HydrophobicContact CE-CG2 3.94Å; V348-V410 HydrophobicContact CG2-CG1 4.31Å; L374-V410 HydrophobicContact CD1-CB 4.09Å; L376-V410 HydrophobicContact CD1-CG1 4.13Å; L376-V410 HydrophobicContact CD2-CG1 3.96Å; W388-V410 HydrophobicContact CH2-CG1 4.22Å; W388-V410 HydrophobicContact CH2-CG2 4.04Å; W388-V410 HydrophobicContact CZ3-CG1 4.43Å; W388-V410 HydrophobicContact CZ3-CG2 4.1Å; G394-V410 WeakPolarHBondContact O-CG2 3.04Å; G394-V410 PolarHBondContact O-N 2.92Å; W408-V410 HydrophobicContact CB-CG1 4.49Å; V410-T413 PolarHBondContact O-OG1 3.45Å
411N89.5Confident85.3Confident95 Ų9566.1 Ų66.151%0.50832%0.318SS..THydrogen-bonded Turntrans-83.5-19.9174.4-61.4-48.8000112.5T393 D409 T413T393-N411 PolarHBondContact O-ND2 2.85Å; D409-N411 PolarHBondContact O-N 3.32Å; D409-N411 VanDerWaalsContact O-N 3.16Å; D409-N411 WeakPolarHBondContact OD1-CB 3.18Å; D409-N411 PolarHBondContact OD1-N 3.21Å; N411-T413 VanDerWaalsContact C-N 3.28Å
412R83Confident85.3Confident171 Ų17161.3 Ų61.365%0.64530%0.304SS*.SBendtrans-74.2-19.2176.7-74.8176.3-168.6-147.6-2.8113.1D409 A414D409-R412 HydrophobicContact CB-CG 4.2Å; D409-R412 PolarHBondContact O-N 2.87Å; D409-R412 VanDerWaalsContact O-N 3.15Å; D409-R412 WeakPolarHBondContact OD2-CD 3.24Å; D409-R412 VanDerWaalsContact OD2-CG 3.28Å; D409-R412 WeakPolarHBondContact OD2-CG 3.38Å; D409-R412 IonicContact OD2-CZ 3.77Å; D409-R412 IonicContact OD2-NE 2.78Å; D409-R412 PolarHBondContact OD2-NE 3.25Å; R412-A414 PolarHBondContact O-N 3.03Å
413T76.1Confident85.3Confident24 Ų2462.2 Ų62.215%0.14731%0.308CS..SBendtrans-69.3118.5-177.1-30.70000109.9L374 V410 N411 R415 N417 V419 C420L374-T413 HydrophobicContact CD2-CG2 4.12Å; V410-T413 PolarHBondContact O-OG1 3.45Å; N411-T413 VanDerWaalsContact C-N 3.28Å; T413-R415 PolarHBondContact O-N 3.1Å; T413-N417 HydrophobicContact CG2-CB 4.16Å; T413-N417 WeakPolarHBondContact CG2-O 3.12Å; T413-V419 WeakPolarHBondContact CG2-O 3.05Å; T413-C420 HydrophobicContact CG2-CB 4.03Å; T413-C420 WeakPolarHBondContact OG1-CB 3.29Å; T413-C420 PolarHBondContact OG1-SG 3.22Å
414A61.8Low85.3Confident59 Ų5964.4 Ų64.449%0.48832%0.323SS..  trans-57139.5175.800000110R412 R416 N417R412-A414 PolarHBondContact O-N 3.03Å; A414-R416 PolarHBondContact O-N 2.95Å; A414-N417 PolarHBondContact O-N 2.82Å
415R62.4Low85.2Confident255 Ų25568.3 Ų68.396%0.96234%0.341SS*.THydrogen-bonded Turntrans-52-19.1-177.4-74.2-173.9178177.40.7115.3T413T413-R415 PolarHBondContact O-N 3.1Å
416R60.3Low85Confident242 Ų24270.3 Ų70.391%0.91335%0.348SS*.THydrogen-bonded Turntrans-89.4-20.8177.4-73.9-175175169.1-1114.1A414A414-R416 PolarHBondContact O-N 2.95Å
417N65.7Low84.5Confident101 Ų10175.9 Ų75.954%0.5438%0.377SS..  trans-93.6114.1180-742000109.2T413 A414 V419T413-N417 HydrophobicContact CG2-CB 4.16Å; T413-N417 WeakPolarHBondContact CG2-O 3.12Å; A414-N417 PolarHBondContact O-N 2.82Å; N417-V419 PolarHBondContact O-N 3.07Å
418S83.7Confident83.7Confident60 Ų6077.1 Ų77.142%0.4238%0.382SS..SBendtrans-77.52.8171.1570000112.9L374 K375L374-S418 CarbonylContact C-O 3.53Å; L374-S418 WeakPolarHBondContact CA-O 3.33Å; K375-S418 PolarHBondContact N-O 3.16Å
419V88.6Confident82.5Confident62 Ų6285 Ų8538%0.37642%0.423SS..EExtended strand (participates in β ladder)trans-121.8129.1-177.3-176.70000109.6K375 K377 T413 N417K375-V419 WeakPolarHBondContact O-CA 3.1Å; K377-V419 HydrophobicContact CD-CG1 3.82Å; K377-V419 HydrophobicContact CG-CG1 3.95Å; T413-V419 WeakPolarHBondContact CG2-O 3.05Å; N417-V419 PolarHBondContact O-N 3.07Å
420C90.3Very high81.6Confident10 Ų1087.8 Ų87.87%0.06846%0.455CS..EExtended strand (participates in β ladder)trans-115.6127173.9-169.80000109.6K375 L376 K377 T413K375-C420 PolarHBondContact O-N 2.87Å; L376-C420 WeakPolarHBondContact CA-O 3.29Å; L376-C420 HydrophobicContact CD2-CB 3.46Å; L376-C420 VanDerWaalsContact CD2-CB 3.46Å; K377-C420 PolarHBondContact N-O 3.18Å; T413-C420 HydrophobicContact CG2-CB 4.03Å; T413-C420 WeakPolarHBondContact OG1-CB 3.29Å; T413-C420 PolarHBondContact OG1-SG 3.22Å
421S90.1Very high81.3Confident90 Ų9087.2 Ų87.263%0.62945%0.452SS*.  trans-81.9159168.7570000110.7W408W408-S421 VanDerWaalsContact CD1-C 3.46Å; W408-S421 VanDerWaalsContact CD1-O 3.25Å
422T90.7Very high81.4Confident32 Ų3284.3 Ų84.320%0.19644%0.439CS..  trans-59.8150.7172.347.60000111.8K377 C406 L407 W408 E425K377-T422 WeakPolarHBondContact O-CG2 3.27Å; C406-T422 HydrophobicContact CB-CG2 3.76Å; L407-T422 CarbonylContact O-C 3.52Å; L407-T422 WeakPolarHBondContact O-CA 3.43Å; W408-T422 HydrophobicContact CD2-CG2 4.38Å; W408-T422 HydrophobicContact CZ2-CG2 3.89Å; T422-E425 WeakPolarHBondContact CB-OE1 3.32Å; T422-E425 HydrophobicContact CG2-CG 3.75Å; T422-E425 VanDerWaalsContact CG2-OE1 3.3Å; T422-E425 WeakPolarHBondContact CG2-OE1 3.28Å; T422-E425 PolarHBondContact OG1-OE1 3.18Å
423I90.5Very high82.1Confident63 Ų6376.2 Ų76.232%0.32341%0.408SS..SBendtrans-81.9-41.4163-60.8170.4000109.5Y395 L407 D409Y395-I423 HydrophobicContact CE1-CD1 4.29Å; L407-I423 HydrophobicContact CD2-CB 4.41Å; L407-I423 HydrophobicContact CG-CB 4.35Å; L407-I423 HydrophobicContact CG-CD1 4.33Å; L407-I423 PolarHBondContact O-N 2.94Å; D409-I423 HydrophobicContact CB-CD1 3.28Å; D409-I423 HydrophobicContact CB-CG1 4.17Å
424S91.1Very high83Confident47 Ų4776.2 Ų76.233%0.32941%0.407SS..EExtended strand (participates in β ladder)trans-153148.5-175.6-560000109.4L407L407-S424 PolarHBondContact N-O 3.41Å
425E91Very high84.7Confident90 Ų9074.2 Ų74.242%0.42139%0.388SS..EExtended strand (participates in β ladder)trans-132.5131179.6-69169.5-172.600107.5V404 V405 T422V404-E425 HydrophobicContact CG1-CB 4.25Å; V404-E425 HydrophobicContact CG1-CG 4.45Å; V405-E425 WeakPolarHBondContact O-CA 3.49Å; T422-E425 WeakPolarHBondContact CB-OE1 3.32Å; T422-E425 HydrophobicContact CG2-CG 3.75Å; T422-E425 VanDerWaalsContact CG2-OE1 3.3Å; T422-E425 WeakPolarHBondContact CG2-OE1 3.28Å; T422-E425 PolarHBondContact OG1-OE1 3.18Å
426W91.8Very high86.3Confident43 Ų4362.2 Ų62.216%0.16334%0.343CS..EExtended strand (participates in β ladder)trans-110.8128.3170-61.9-105.2000107V404 V405 L407 F446 E458 I460V404-W426 CarbonylContact C-O 3.58Å; V404-W426 WeakPolarHBondContact CA-O 3.19Å; V405-W426 HydrophobicContact CB-CB 4.28Å; V405-W426 HydrophobicContact CB-CE3 4.37Å; V405-W426 HydrophobicContact CG1-CE3 4.3Å; V405-W426 PolarHBondContact N-O 2.92Å; V405-W426 PolarHBondContact O-N 3.41Å; L407-W426 HydrophobicContact CB-CH2 4.13Å; L407-W426 HydrophobicContact CB-CZ3 3.72Å; L407-W426 HydrophobicContact CD2-CH2 4.06Å; W426-F446 AromaticContact CD2-CZ 3.95Å; W426-F446 HydrophobicContact CD2-CZ 3.95Å; W426-F446 AromaticContact CE2-CZ 3.88Å; W426-F446 AromaticContact CE3-CZ 3.86Å; W426-F446 HydrophobicContact CE3-CZ 3.86Å; W426-F446 AromaticContact CH2-CE1 3.76Å; W426-F446 HydrophobicContact CH2-CE1 3.76Å; W426-F446 AromaticContact CH2-CZ 3.74Å; W426-F446 HydrophobicContact CH2-CZ 3.74Å; W426-F446 AromaticContact CZ2-CE1 3.85Å; W426-F446 HydrophobicContact CZ2-CE1 3.85Å; W426-F446 AromaticContact CZ2-CZ 3.79Å; W426-F446 HydrophobicContact CZ2-CZ 3.79Å; W426-F446 HydrophobicContact CZ3-CE1 4.18Å; W426-F446 AromaticContact CZ3-CZ 3.76Å; W426-F446 HydrophobicContact CZ3-CZ 3.76Å; W426-E458 VanDerWaalsContact NE1-CD 3.28Å; W426-E458 PolarHBondContact NE1-OE2 3.44Å; W426-I460 HydrophobicContact CH2-CG2 4.07Å; W426-I460 HydrophobicContact CZ2-CG2 4.38Å
427I86.5Confident88.1Confident117 Ų11751.7 Ų51.760%0.631%0.307SS*.EExtended strand (participates in β ladder)trans-112.5120.4-174.9-57.2175.2000108V404V404-I427 HydrophobicContact CG2-CG1 4.37Å
428E79.3Confident89.6Confident28 Ų2847 Ų4713%0.13128%0.281CS..  trans-98118.2170.3-164.2156.7-142.800109.2G403 G430 A431 N450G403-E428 WeakPolarHBondContact O-CB 3.47Å; G403-E428 PolarHBondContact O-N 3.18Å; E428-G430 PolarHBondContact O-N 3.41Å; E428-A431 HydrophobicContact CG-CB 4.12Å; E428-N450 PolarHBondContact OE1-ND2 3.43Å; E428-N450 VanDerWaalsContact OE2-CB 3.32Å; E428-N450 WeakPolarHBondContact OE2-CB 3.3Å; E428-N450 PolarHBondContact OE2-ND2 2.91Å; E428-N450 VanDerWaalsContact OE2-ND2 3.09Å
429I72.6Confident90.2Very high166 Ų16644.6 Ų44.685%0.85126%0.264SS*.SBendtrans-79.5115.5-173.2-58.8174.1000108.7
430G76.3Confident90.3Very high74 Ų7442.7 Ų42.776%0.76325%0.253SS*.SBendtrans89-6.3169.100000116.1E428E428-G430 PolarHBondContact O-N 3.41Å
431A87.1Confident90.3Very high3 Ų345.6 Ų45.63%0.02527%0.267CS..  trans-120.5121.2-177.900000112G403 E428 N450 E452G403-A431 WeakPolarHBondContact CA-O 3.23Å; E428-A431 HydrophobicContact CG-CB 4.12Å; A431-N450 HydrophobicContact CB-CB 4.13Å; A431-E452 HydrophobicContact CB-CB 4.32Å; A431-E452 HydrophobicContact CB-CG 3.49Å; A431-E452 VanDerWaalsContact CB-CG 3.49Å
432P91.4Very high90.5Very high34 Ų3443.4 Ų43.422%0.22125%0.251CS..  trans-53.6134.9167.4-32.238.8000113R401 N450 D451R401-P432 HydrophobicContact CB-CB 4.46Å; R401-P432 HydrophobicContact CG-CB 4.46Å; P432-N450 WeakPolarHBondContact O-CA 3.44Å; P432-N450 VanDerWaalsContact O-CB 3.23Å; P432-N450 WeakPolarHBondContact O-CB 3.38Å; P432-D451 HydrophobicContact CB-CB 4.5Å; P432-D451 WeakPolarHBondContact CB-OD2 3.48Å; P432-D451 HydrophobicContact CG-CB 4.5Å; P432-D451 VanDerWaalsContact CG-OD2 3.32Å; P432-D451 WeakPolarHBondContact CG-OD2 3.41Å; P432-D451 PolarHBondContact O-N 3.01Å; P432-D451 VanDerWaalsContact O-N 3.14Å
433V96.2Very high90.6Very high1 Ų143.3 Ų43.31%0.00625%0.251CS..EExtended strand (participates in β ladder)trans-87.3117.4170.8179.10000109.2S400 V405 V436 Y448S400-V433 PolarHBondContact O-N 3.36Å; V405-V433 HydrophobicContact CG2-CG1 4.04Å; V405-V433 HydrophobicContact CG2-CG2 3.96Å; V433-V436 HydrophobicContact CG1-CG1 3.97Å; V433-Y448 HydrophobicContact CG1-CD2 4.12Å; V433-Y448 HydrophobicContact CG2-CD2 4.25Å; V433-Y448 HydrophobicContact CG2-CE2 4.48Å
434N94.9Very high90.7Very high24 Ų2440.9 Ų40.913%0.12824%0.239CC..EExtended strand (participates in β ladder)trans-84-48-173.3-72-34.9000112.7G385 V449 N450 D451 V479G385-N434 PolarHBondContact N-O 3.08Å; N434-V449 HydrophobicContact CB-CG2 4.44Å; N434-V449 PolarHBondContact N-O 2.72Å; N434-N450 VanDerWaalsContact ND2-C 3.3Å; N434-N450 PolarHBondContact ND2-O 3.01Å; N434-D451 PolarHBondContact ND2-N 3.12Å; N434-D451 PolarHBondContact ND2-OD1 3.14Å; N434-D451 PolarHBondContact OD1-OD1 3.36Å; N434-V479 WeakPolarHBondContact CB-O 3.41Å; N434-V479 PolarHBondContact ND2-O 2.04Å
435D97.3Very high90.9Very high17 Ų1740.2 Ų40.29%0.09123%0.233CC..EExtended strand (participates in β ladder)trans-148.1158.1-179.4-162.816.6000112.2Y448 V449 V482D435-Y448 VanDerWaalsContact O-CA 3.32Å; D435-Y448 WeakPolarHBondContact O-CA 3.32Å; D435-Y448 WeakPolarHBondContact O-CB 3.2Å; D435-V449 HydrophobicContact CB-CG2 4.03Å; D435-V449 PolarHBondContact O-N 3.32Å; D435-V449 VanDerWaalsContact O-N 3.12Å; D435-V482 HydrophobicContact CB-CG1 4.1Å; D435-V482 PolarHBondContact OD2-N 3.48Å
436V97.8Very high91.2Very high3 Ų336 Ų362%0.01821%0.213CC..EExtended strand (participates in β ladder)trans-137.6141.1-179.7-54.90000110.4S387 L397 V405 V433 A447S387-V436 WeakPolarHBondContact CB-O 3.3Å; L397-V436 HydrophobicContact CB-CG2 3.95Å; V405-V436 HydrophobicContact CG1-CG1 4.31Å; V405-V436 HydrophobicContact CG2-CG1 4.47Å; V433-V436 HydrophobicContact CG1-CG1 3.97Å; V436-A447 WeakPolarHBondContact CA-O 3.28Å
437C97.4Very high91.4Very high21 Ų2134 Ų3414%0.14221%0.206CC..EExtended strand (participates in β ladder)trans-142.6126.8179.1-171.60000112.5F446 A447 V482 C484C437-F446 WeakPolarHBondContact O-CA 3.42Å; C437-F446 WeakPolarHBondContact O-CB 3.47Å; C437-A447 PolarHBondContact N-O 3.14Å; C437-A447 PolarHBondContact O-N 2.7Å; C437-V482 HydrophobicContact CB-CG1 3.99Å; C437-C484 VanDerWaalsContact SG-CB 3.56Å; C437-C484 PolarHBondContact SG-N 2.89Å; C437-C484 VanDerWaalsContact SG-SG 3.68Å
438W97.9Very high92Very high3 Ų329 Ų291%0.01118%0.179CC..EExtended strand (participates in β ladder)trans-67.7144.8166.7-77.6102.4000111.7S387 N389 L397 L407 S440 F446 I460 C484S387-W438 PolarHBondContact O-NE1 3.48Å; S387-W438 VanDerWaalsContact O-NE1 3.1Å; S387-W438 PolarHBondContact OG-N 3.47Å; N389-W438 HydrophobicContact CB-CD2 4.07Å; N389-W438 HydrophobicContact CB-CG 4.21Å; N389-W438 HydrophobicContact CB-CZ2 4.33Å; N389-W438 VanDerWaalsContact ND2-CE3 3.27Å; N389-W438 WeakPolarHBondContact ND2-CZ3 3.33Å; L397-W438 HydrophobicContact CD1-CD2 3.6Å; L397-W438 HydrophobicContact CD1-CE3 4.22Å; L397-W438 HydrophobicContact CD1-CG 3.95Å; L397-W438 HydrophobicContact CD1-CH2 4.18Å; L397-W438 HydrophobicContact CD1-CZ2 3.6Å; L397-W438 HydrophobicContact CD1-CZ3 4.47Å; L397-W438 VanDerWaalsContact CD1-NE1 3.34Å; L397-W438 HydrophobicContact CD2-CZ2 4.03Å; L397-W438 HydrophobicContact CG-CD2 4.31Å; L397-W438 VanDerWaalsContact CG-CE2 3.43Å; L397-W438 HydrophobicContact CG-CH2 4.34Å; L397-W438 HydrophobicContact CG-CZ2 3.48Å; L397-W438 VanDerWaalsContact CG-CZ2 3.48Å; L407-W438 HydrophobicContact CD1-CH2 4.05Å; L407-W438 HydrophobicContact CD1-CZ2 3.66Å; W438-S440 PolarHBondContact O-N 3.3Å; W438-F446 HydrophobicContact CD2-CB 4.25Å; W438-F446 HydrophobicContact CE3-CB 3.91Å; W438-F446 HydrophobicContact CH2-CD1 4.31Å; W438-F446 HydrophobicContact CZ3-CB 4.28Å; W438-F446 HydrophobicContact CZ3-CD1 4.06Å; W438-I460 HydrophobicContact CH2-CD1 4.13Å; W438-I460 HydrophobicContact CH2-CG2 3.98Å; W438-I460 HydrophobicContact CZ3-CD1 4.4Å; W438-I460 HydrophobicContact CZ3-CG2 4.33Å; W438-C484 WeakPolarHBondContact O-CB 3.36Å
439N95.7Very high92.8Very high9 Ų927.6 Ų27.65%0.04817%0.173CC..  trans-71.7119.5162.8-170.4-61.2000109.5M441 S442 V445 S489N439-M441 PolarHBondContact O-N 2.73Å; N439-M441 PolarHBondContact OD1-N 3.17Å; N439-S442 CarbonylContact O-C 3.58Å; N439-S442 PolarHBondContact OD1-N 2.98Å; N439-V445 HydrophobicContact CB-CB 4.18Å; N439-V445 HydrophobicContact CB-CG1 4.45Å; N439-V445 VanDerWaalsContact CB-O 3.3Å; N439-V445 WeakPolarHBondContact CB-O 3.2Å; N439-V445 PolarHBondContact N-O 3.41Å; N439-S489 PolarHBondContact ND2-O 3.43Å
440S89.8Confident93.9Very high21 Ų2119.8 Ų19.815%0.14713%0.133CC..SBendtrans-65.9-25.6-174.9-660000113.6R391 W438R391-S440 PolarHBondContact NE-O 2.99Å; W438-S440 PolarHBondContact O-N 3.3Å
441M90.7Very high94.5Very high72 Ų7219 Ų1936%0.35511%0.111SC..SBendtrans-100.1-28.5-175.7-65.5-60.7-76.800112.6R391 N439 P443R391-M441 PolarHBondContact NH1-O 3.39Å; R391-M441 PolarHBondContact NH2-SD 3.12Å; N439-M441 PolarHBondContact O-N 2.73Å; N439-M441 PolarHBondContact OD1-N 3.17Å; M441-P443 WeakPolarHBondContact O-CD 3.34Å
442S93.5Very high94.7Very high43 Ų4324.9 Ų24.930%0.30114%0.138SC..  trans-114.690.6179.2-66.10000110.2N439 T444 V445N439-S442 CarbonylContact O-C 3.58Å; N439-S442 PolarHBondContact OD1-N 2.98Å; S442-T444 PolarHBondContact O-N 2.82Å; S442-V445 PolarHBondContact O-N 3.27Å
443P93.2Very high94.7Very high30 Ų3023.3 Ų23.320%0.19513%0.128CC..THydrogen-bonded Turntrans-73.18-168.332.5-38.5000114.8N389 R391 R392 M441N389-P443 PolarHBondContact ND2-O 2.87Å; R391-P443 HydrophobicContact CB-CB 4.04Å; R391-P443 HydrophobicContact CB-CG 4.44Å; R392-P443 HydrophobicContact CG-CB 4.05Å; M441-P443 WeakPolarHBondContact O-CD 3.34Å
444T94Very high94.6Very high12 Ų1225.2 Ų25.27%0.07414%0.138CC..THydrogen-bonded Turntrans-106.8-12.7173.158.60000112.6S442 D459 I460 R461S442-T444 PolarHBondContact O-N 2.82Å; T444-D459 WeakPolarHBondContact CB-OD1 3.46Å; T444-D459 CarbonylContact O-C 3.52Å; T444-D459 WeakPolarHBondContact O-CA 3.46Å; T444-D459 PolarHBondContact OG1-OD1 3.04Å; T444-D459 PolarHBondContact OG1-OD2 3.43Å; T444-I460 HydrophobicContact CG2-CD1 4.3Å; T444-I460 HydrophobicContact CG2-CG1 4.16Å; T444-I460 PolarHBondContact O-N 2.93Å; T444-R461 HydrophobicContact CG2-CG 3.91Å; T444-R461 PolarHBondContact OG1-NE 3.22Å
445V95.2Very high94.6Very high34 Ų3424.1 Ų24.121%0.20613%0.132CC..EExtended strand (participates in β ladder)trans-107.6138.7-174.2-179.80000109.9N439 S442 E458 D459N439-V445 HydrophobicContact CB-CB 4.18Å; N439-V445 HydrophobicContact CB-CG1 4.45Å; N439-V445 VanDerWaalsContact CB-O 3.3Å; N439-V445 WeakPolarHBondContact CB-O 3.2Å; N439-V445 PolarHBondContact N-O 3.41Å; S442-V445 PolarHBondContact O-N 3.27Å; V445-E458 VanDerWaalsContact CA-O 3.26Å; V445-E458 WeakPolarHBondContact CA-O 3.24Å; V445-D459 HydrophobicContact CG2-CB 4.31Å; V445-D459 WeakPolarHBondContact CG2-OD2 3.41Å
446F96.7Very high94.5Very high1 Ų123.4 Ų23.40%0.00413%0.128CC..EExtended strand (participates in β ladder)trans-142.1164.6172.866.4-87.8000111L397 V405 W426 C437 W438 Y448 F457 E458 I460L397-F446 HydrophobicContact CD1-CB 3.4Å; L397-F446 VanDerWaalsContact CD1-CB 3.4Å; L397-F446 HydrophobicContact CD1-CD1 3.93Å; L397-F446 HydrophobicContact CD1-CD2 3.67Å; L397-F446 HydrophobicContact CD1-CE2 4.38Å; L397-F446 HydrophobicContact CD1-CG 3.39Å; L397-F446 HydrophobicContact CD2-CD1 4.39Å; L397-F446 HydrophobicContact CD2-CD2 4.41Å; L397-F446 HydrophobicContact CD2-CE1 4.31Å; L397-F446 HydrophobicContact CD2-CE2 4.32Å; L397-F446 HydrophobicContact CD2-CG 4.43Å; L397-F446 HydrophobicContact CD2-CZ 4.26Å; V405-F446 HydrophobicContact CG1-CE2 3.93Å; V405-F446 HydrophobicContact CG1-CZ 4.46Å; W426-F446 AromaticContact CD2-CZ 3.95Å; W426-F446 HydrophobicContact CD2-CZ 3.95Å; W426-F446 AromaticContact CE2-CZ 3.88Å; W426-F446 AromaticContact CE3-CZ 3.86Å; W426-F446 HydrophobicContact CE3-CZ 3.86Å; W426-F446 AromaticContact CH2-CE1 3.76Å; W426-F446 HydrophobicContact CH2-CE1 3.76Å; W426-F446 AromaticContact CH2-CZ 3.74Å; W426-F446 HydrophobicContact CH2-CZ 3.74Å; W426-F446 AromaticContact CZ2-CE1 3.85Å; W426-F446 HydrophobicContact CZ2-CE1 3.85Å; W426-F446 AromaticContact CZ2-CZ 3.79Å; W426-F446 HydrophobicContact CZ2-CZ 3.79Å; W426-F446 HydrophobicContact CZ3-CE1 4.18Å; W426-F446 AromaticContact CZ3-CZ 3.76Å; W426-F446 HydrophobicContact CZ3-CZ 3.76Å; C437-F446 WeakPolarHBondContact O-CA 3.42Å; C437-F446 WeakPolarHBondContact O-CB 3.47Å; W438-F446 HydrophobicContact CD2-CB 4.25Å; W438-F446 HydrophobicContact CE3-CB 3.91Å; W438-F446 HydrophobicContact CH2-CD1 4.31Å; W438-F446 HydrophobicContact CZ3-CB 4.28Å; W438-F446 HydrophobicContact CZ3-CD1 4.06Å; F446-Y448 HydrophobicContact CD2-CD1 4.26Å; F446-Y448 AromaticContact CE2-CD1 3.84Å; F446-Y448 HydrophobicContact CE2-CD1 3.84Å; F446-Y448 HydrophobicContact CE2-CE1 4.26Å; F446-F457 WeakPolarHBondContact O-CA 3.47Å; F446-E458 HydrophobicContact CD1-CB 3.98Å; F446-E458 HydrophobicContact CD2-CB 4.19Å; F446-E458 HydrophobicContact CE1-CB 3.42Å; F446-E458 VanDerWaalsContact CE1-CB 3.42Å; F446-E458 HydrophobicContact CE1-CG 4.38Å; F446-E458 HydrophobicContact CE2-CB 3.67Å; F446-E458 HydrophobicContact CE2-CG 3.95Å; F446-E458 HydrophobicContact CG-CB 4.34Å; F446-E458 HydrophobicContact CZ-CB 3.26Å; F446-E458 HydrophobicContact CZ-CG 3.74Å; F446-E458 PolarHBondContact N-O 2.91Å; F446-E458 PolarHBondContact O-N 3.32Å; F446-I460 HydrophobicContact CD1-CG2 4.12Å; F446-I460 HydrophobicContact CE1-CG2 3.79Å
447A96.9Very high94.3Very high0 Ų023.9 Ų23.90%013%0.13CC..EExtended strand (participates in β ladder)trans-126.815217500000110.8V436 C437 L455 T456 F457 V482V436-A447 WeakPolarHBondContact CA-O 3.28Å; C437-A447 PolarHBondContact N-O 3.14Å; C437-A447 PolarHBondContact O-N 2.7Å; A447-L455 HydrophobicContact CB-CD1 4.1Å; A447-T456 CarbonylContact C-O 3.29Å; A447-T456 WeakPolarHBondContact CA-O 3.32Å; A447-F457 HydrophobicContact CB-CD1 3.83Å; A447-F457 HydrophobicContact CB-CE1 3.82Å; A447-V482 HydrophobicContact CB-CG2 4.18Å
448Y97.5Very high94.2Very high12 Ų1223.2 Ų23.25%0.04713%0.125CC..EExtended strand (participates in β ladder)trans-145.7160172.766-90.3000111.4V405 V433 D435 F446 T456 E458V405-Y448 HydrophobicContact CG2-CD1 3.95Å; V405-Y448 HydrophobicContact CG2-CD2 3.86Å; V405-Y448 HydrophobicContact CG2-CE1 4.15Å; V405-Y448 HydrophobicContact CG2-CE2 4.09Å; V405-Y448 HydrophobicContact CG2-CG 3.77Å; V433-Y448 HydrophobicContact CG1-CD2 4.12Å; V433-Y448 HydrophobicContact CG2-CD2 4.25Å; V433-Y448 HydrophobicContact CG2-CE2 4.48Å; D435-Y448 VanDerWaalsContact O-CA 3.32Å; D435-Y448 WeakPolarHBondContact O-CA 3.32Å; D435-Y448 WeakPolarHBondContact O-CB 3.2Å; F446-Y448 HydrophobicContact CD2-CD1 4.26Å; F446-Y448 AromaticContact CE2-CD1 3.84Å; F446-Y448 HydrophobicContact CE2-CD1 3.84Å; F446-Y448 HydrophobicContact CE2-CE1 4.26Å; Y448-T456 HydrophobicContact CD1-CG2 4.3Å; Y448-T456 HydrophobicContact CE1-CG2 3.46Å; Y448-T456 VanDerWaalsContact CE1-CG2 3.46Å; Y448-T456 HydrophobicContact CE2-CG2 4.21Å; Y448-T456 VanDerWaalsContact CZ-CB 3.46Å; Y448-T456 VanDerWaalsContact CZ-CG2 3.41Å; Y448-T456 PolarHBondContact N-O 3.12Å; Y448-T456 PolarHBondContact O-N 2.96Å; Y448-T456 WeakPolarHBondContact OH-CG2 3.23Å; Y448-E458 HydrophobicContact CE1-CG 3.8Å
449V96.9Very high93.9Very high0 Ų023.7 Ų23.70%013%0.128CC..EExtended strand (participates in β ladder)trans-135154.7-174.6-68.20000111.7N434 D435 L454 L455 V479 V482 T494N434-V449 HydrophobicContact CB-CG2 4.44Å; N434-V449 PolarHBondContact N-O 2.72Å; D435-V449 HydrophobicContact CB-CG2 4.03Å; D435-V449 PolarHBondContact O-N 3.32Å; D435-V449 VanDerWaalsContact O-N 3.12Å; V449-L454 VanDerWaalsContact CA-O 3.3Å; V449-L454 WeakPolarHBondContact CA-O 3.16Å; V449-L455 HydrophobicContact CG1-CB 4.34Å; V449-L455 HydrophobicContact CG1-CD1 3.69Å; V449-V479 HydrophobicContact CB-CB 3.88Å; V449-V479 HydrophobicContact CB-CG1 3.56Å; V449-V479 HydrophobicContact CG1-CB 4.19Å; V449-V479 HydrophobicContact CG1-CG1 3.48Å; V449-V479 VanDerWaalsContact CG1-CG1 3.48Å; V449-V479 HydrophobicContact CG2-CB 4.5Å; V449-V479 HydrophobicContact CG2-CG1 3.96Å; V449-V482 HydrophobicContact CG1-CB 3.81Å; V449-V482 HydrophobicContact CG1-CG1 4.37Å; V449-V482 HydrophobicContact CG1-CG2 4.23Å; V449-V482 HydrophobicContact CG2-CB 4Å; V449-V482 HydrophobicContact CG2-CG1 4.02Å; V449-T494 HydrophobicContact CG1-CG2 4.12Å
450N94.6Very high93.8Very high1 Ų125.2 Ų25.21%0.00514%0.135CC..EExtended strand (participates in β ladder)trans-138.5-179.3-170.574.76000113.9E428 A431 P432 N434 E452 G453 L454 V479E428-N450 PolarHBondContact OE1-ND2 3.43Å; E428-N450 VanDerWaalsContact OE2-CB 3.32Å; E428-N450 WeakPolarHBondContact OE2-CB 3.3Å; E428-N450 PolarHBondContact OE2-ND2 2.91Å; E428-N450 VanDerWaalsContact OE2-ND2 3.09Å; A431-N450 HydrophobicContact CB-CB 4.13Å; P432-N450 WeakPolarHBondContact O-CA 3.44Å; P432-N450 VanDerWaalsContact O-CB 3.23Å; P432-N450 WeakPolarHBondContact O-CB 3.38Å; N434-N450 VanDerWaalsContact ND2-C 3.3Å; N434-N450 PolarHBondContact ND2-O 3.01Å; N450-E452 VanDerWaalsContact C-N 3.33Å; N450-E452 WeakPolarHBondContact OD1-CA 3.27Å; N450-E452 PolarHBondContact OD1-N 3.41Å; N450-G453 PolarHBondContact O-N 3.14Å; N450-G453 PolarHBondContact OD1-N 3.37Å; N450-G453 VanDerWaalsContact OD1-N 3.12Å; N450-L454 PolarHBondContact N-O 3.28Å; N450-L454 PolarHBondContact OD1-N 2.71Å; N450-V479 PolarHBondContact O-N 2.99Å
451D90.2Very high93.7Very high57 Ų5732.4 Ų32.431%0.30516%0.159SC..THydrogen-bonded Turntrans-74-16.2177.4-80.8-13000115P432 N434 G453 K478P432-D451 HydrophobicContact CB-CB 4.5Å; P432-D451 WeakPolarHBondContact CB-OD2 3.48Å; P432-D451 HydrophobicContact CG-CB 4.5Å; P432-D451 VanDerWaalsContact CG-OD2 3.32Å; P432-D451 WeakPolarHBondContact CG-OD2 3.41Å; P432-D451 PolarHBondContact O-N 3.01Å; P432-D451 VanDerWaalsContact O-N 3.14Å; N434-D451 PolarHBondContact ND2-N 3.12Å; N434-D451 PolarHBondContact ND2-OD1 3.14Å; N434-D451 PolarHBondContact OD1-OD1 3.36Å; D451-G453 PolarHBondContact O-N 2.88Å; D451-K478 HydrophobicContact CB-CB 4.25Å; D451-K478 WeakPolarHBondContact OD1-CB 2.98Å; D451-K478 WeakPolarHBondContact OD1-CD 3.4Å
452E90.7Very high93.2Very high128 Ų12831.7 Ų31.760%0.59816%0.159SC*.THydrogen-bonded Turntrans-84.15.5175.4-65.2-70141.200112.7A431 N450 L454A431-E452 HydrophobicContact CB-CB 4.32Å; A431-E452 HydrophobicContact CB-CG 3.49Å; A431-E452 VanDerWaalsContact CB-CG 3.49Å; N450-E452 VanDerWaalsContact C-N 3.33Å; N450-E452 WeakPolarHBondContact OD1-CA 3.27Å; N450-E452 PolarHBondContact OD1-N 3.41Å; E452-L454 VanDerWaalsContact C-N 3.34Å; E452-L454 HydrophobicContact CB-CD1 4.43Å; E452-L454 HydrophobicContact CB-CG 4.19Å; E452-L454 PolarHBondContact O-N 3.22Å
453G91.8Very high91.9Very high0 Ų039.7 Ų39.70%019%0.188CC..SBendtrans76.519179.300000114.1N450 D451 A473 C474 G477N450-G453 PolarHBondContact O-N 3.14Å; N450-G453 PolarHBondContact OD1-N 3.37Å; N450-G453 VanDerWaalsContact OD1-N 3.12Å; D451-G453 PolarHBondContact O-N 2.88Å; G453-A473 PolarHBondContact O-N 2.65Å; G453-C474 PolarHBondContact O-N 2.91Å; G453-C474 VanDerWaalsContact O-N 3.09Å; G453-G477 WeakPolarHBondContact CA-O 3.32Å; G453-G477 PolarHBondContact N-O 2.77Å
454L94Very high90.3Very high42 Ų4243.8 Ų43.822%0.2221%0.207CC..EExtended strand (participates in β ladder)trans-92.4142-178.6-55.3-179.9000112.2V449 N450 E452 V470 V471V449-L454 VanDerWaalsContact CA-O 3.3Å; V449-L454 WeakPolarHBondContact CA-O 3.16Å; N450-L454 PolarHBondContact N-O 3.28Å; N450-L454 PolarHBondContact OD1-N 2.71Å; E452-L454 VanDerWaalsContact C-N 3.34Å; E452-L454 HydrophobicContact CB-CD1 4.43Å; E452-L454 HydrophobicContact CB-CG 4.19Å; E452-L454 PolarHBondContact O-N 3.22Å; L454-V470 HydrophobicContact CB-CG1 4.22Å; L454-V470 HydrophobicContact CD1-CG1 4.13Å; L454-V470 HydrophobicContact CD2-CG1 4.29Å; L454-V470 HydrophobicContact CG-CG1 4.46Å; L454-V471 WeakPolarHBondContact CA-O 3.02Å
455L95.6Very high89.1Confident0 Ų050.6 Ų50.60%025%0.249CC..EExtended strand (participates in β ladder)trans-110.1114.8165.9172.163.9000108.7A447 V449 F457 V471 A473 V482 V492 T494 W504A447-L455 HydrophobicContact CB-CD1 4.1Å; V449-L455 HydrophobicContact CG1-CB 4.34Å; V449-L455 HydrophobicContact CG1-CD1 3.69Å; L455-F457 HydrophobicContact CD1-CE2 4.42Å; L455-F457 HydrophobicContact CD1-CZ 4.29Å; L455-F457 HydrophobicContact CD2-CE2 3.66Å; L455-F457 HydrophobicContact CD2-CZ 3.64Å; L455-F457 HydrophobicContact CG-CD2 4.44Å; L455-F457 HydrophobicContact CG-CE2 3.69Å; L455-F457 HydrophobicContact CG-CZ 3.93Å; L455-V471 PolarHBondContact N-O 3.13Å; L455-V471 PolarHBondContact O-N 3.43Å; L455-A473 HydrophobicContact CB-CB 3.91Å; L455-V482 HydrophobicContact CD1-CG2 3.94Å; L455-V492 HydrophobicContact CD1-CG1 4.5Å; L455-T494 HydrophobicContact CB-CG2 4.32Å; L455-T494 HydrophobicContact CD1-CG2 3.93Å; L455-T494 HydrophobicContact CD2-CG2 3.78Å; L455-T494 HydrophobicContact CG-CG2 4.22Å; L455-W504 HydrophobicContact CD2-CB 4.44Å; L455-W504 HydrophobicContact CD2-CD2 4.02Å; L455-W504 HydrophobicContact CD2-CG 3.78Å
456T94.8Very high87.8Confident2 Ų252 Ų521%0.01226%0.261CS..EExtended strand (participates in β ladder)trans-112.4135.3-177.3-59.40000111.1A447 Y448 E458 P467 V470A447-T456 CarbonylContact C-O 3.29Å; A447-T456 WeakPolarHBondContact CA-O 3.32Å; Y448-T456 HydrophobicContact CD1-CG2 4.3Å; Y448-T456 HydrophobicContact CE1-CG2 3.46Å; Y448-T456 VanDerWaalsContact CE1-CG2 3.46Å; Y448-T456 HydrophobicContact CE2-CG2 4.21Å; Y448-T456 VanDerWaalsContact CZ-CB 3.46Å; Y448-T456 VanDerWaalsContact CZ-CG2 3.41Å; Y448-T456 PolarHBondContact N-O 3.12Å; Y448-T456 PolarHBondContact O-N 2.96Å; Y448-T456 WeakPolarHBondContact OH-CG2 3.23Å; T456-E458 HydrophobicContact CG2-CG 4.41Å; T456-P467 HydrophobicContact CG2-CB 3.59Å; T456-P467 HydrophobicContact CG2-CG 4.44Å; T456-V470 HydrophobicContact CG2-CG2 3.94Å
457F94.1Very high86.7Confident13 Ų1354.5 Ų54.56%0.05728%0.277CS..EExtended strand (participates in β ladder)trans-111.1138.2175.5-64.6-85.9000110.8F446 A447 L455 V468 S469 V492 T506 L509F446-F457 WeakPolarHBondContact O-CA 3.47Å; A447-F457 HydrophobicContact CB-CD1 3.83Å; A447-F457 HydrophobicContact CB-CE1 3.82Å; L455-F457 HydrophobicContact CD1-CE2 4.42Å; L455-F457 HydrophobicContact CD1-CZ 4.29Å; L455-F457 HydrophobicContact CD2-CE2 3.66Å; L455-F457 HydrophobicContact CD2-CZ 3.64Å; L455-F457 HydrophobicContact CG-CD2 4.44Å; L455-F457 HydrophobicContact CG-CE2 3.69Å; L455-F457 HydrophobicContact CG-CZ 3.93Å; F457-V468 WeakPolarHBondContact O-CB 3.47Å; F457-V468 PolarHBondContact O-N 2.78Å; F457-V468 VanDerWaalsContact O-N 3.11Å; F457-S469 PolarHBondContact N-O 3.22Å; F457-S469 PolarHBondContact O-N 2.77Å; F457-V492 HydrophobicContact CE1-CG2 3.81Å; F457-V492 HydrophobicContact CZ-CB 4.49Å; F457-V492 HydrophobicContact CZ-CG2 4.21Å; F457-T506 HydrophobicContact CD1-CG2 4.43Å; F457-T506 HydrophobicContact CE1-CG2 3.73Å; F457-T506 HydrophobicContact CZ-CG2 4.08Å; F457-L509 HydrophobicContact CD2-CD1 3.8Å; F457-L509 HydrophobicContact CD2-CD2 4.42Å; F457-L509 HydrophobicContact CE2-CD1 3.83Å; F457-L509 HydrophobicContact CE2-CD2 3.6Å; F457-L509 HydrophobicContact CE2-CG 4.39Å; F457-L509 HydrophobicContact CZ-CD2 4.01Å
458E93.8Very high85.9Confident7 Ų758 Ų583%0.03330%0.298CS..EExtended strand (participates in β ladder)trans-135.4149.9-177.5-73.3-67.3179.600111.8W426 V445 F446 Y448 T456 P467W426-E458 VanDerWaalsContact NE1-CD 3.28Å; W426-E458 PolarHBondContact NE1-OE2 3.44Å; V445-E458 VanDerWaalsContact CA-O 3.26Å; V445-E458 WeakPolarHBondContact CA-O 3.24Å; F446-E458 HydrophobicContact CD1-CB 3.98Å; F446-E458 HydrophobicContact CD2-CB 4.19Å; F446-E458 HydrophobicContact CE1-CB 3.42Å; F446-E458 VanDerWaalsContact CE1-CB 3.42Å; F446-E458 HydrophobicContact CE1-CG 4.38Å; F446-E458 HydrophobicContact CE2-CB 3.67Å; F446-E458 HydrophobicContact CE2-CG 3.95Å; F446-E458 HydrophobicContact CG-CB 4.34Å; F446-E458 HydrophobicContact CZ-CB 3.26Å; F446-E458 HydrophobicContact CZ-CG 3.74Å; F446-E458 PolarHBondContact N-O 2.91Å; F446-E458 PolarHBondContact O-N 3.32Å; Y448-E458 HydrophobicContact CE1-CG 3.8Å; T456-E458 HydrophobicContact CG2-CG 4.41Å; E458-P467 WeakPolarHBondContact OE1-CA 3.45Å; E458-P467 VanDerWaalsContact OE1-CB 3.25Å; E458-P467 WeakPolarHBondContact OE1-CB 3.18Å
459D92.3Very high85.5Confident14 Ų1459.5 Ų59.58%0.07531%0.311CS..EExtended strand (participates in β ladder)trans-126120.9171-167.6-47.7000110.5T444 V445 R461 T462 V468T444-D459 WeakPolarHBondContact CB-OD1 3.46Å; T444-D459 CarbonylContact O-C 3.52Å; T444-D459 WeakPolarHBondContact O-CA 3.46Å; T444-D459 PolarHBondContact OG1-OD1 3.04Å; T444-D459 PolarHBondContact OG1-OD2 3.43Å; V445-D459 HydrophobicContact CG2-CB 4.31Å; V445-D459 WeakPolarHBondContact CG2-OD2 3.41Å; D459-R461 PolarHBondContact O-N 2.88Å; D459-R461 WeakPolarHBondContact OD1-CB 3.45Å; D459-R461 VanDerWaalsContact OD1-CG 3.27Å; D459-R461 WeakPolarHBondContact OD1-CG 3.27Å; D459-R461 IonicContact OD1-CZ 3.21Å; D459-R461 PolarHBondContact OD1-N 2.96Å; D459-R461 IonicContact OD1-NE 3.75Å; D459-R461 PolarHBondContact OD1-NE 3.37Å; D459-R461 IonicContact OD1-NH2 3.19Å; D459-R461 IonicContact OD2-CZ 3.51Å; D459-R461 VanDerWaalsContact OD2-CZ 3.31Å; D459-R461 IonicContact OD2-NE 3.91Å; D459-R461 PolarHBondContact OD2-NE 3.06Å; D459-R461 VanDerWaalsContact OD2-NE 3.15Å; D459-R461 IonicContact OD2-NH2 2.92Å; D459-R461 PolarHBondContact OD2-NH2 3.3Å; D459-T462 HydrophobicContact CB-CG2 4.28Å; D459-T462 PolarHBondContact O-N 2.86Å; D459-T462 PolarHBondContact O-OG1 2.82Å; D459-V468 HydrophobicContact CB-CG2 4.01Å
460I92.7Very high85.2Confident41 Ų4162.8 Ų62.821%0.2133%0.33CS..THydrogen-bonded Turntrans-65.8-7.3-177.568.4-176.9000114Y395 L407 W426 W438 T444 F446Y395-I460 HydrophobicContact CE1-CD1 4.37Å; L407-I460 HydrophobicContact CD2-CB 4.37Å; L407-I460 HydrophobicContact CD2-CG2 3.78Å; W426-I460 HydrophobicContact CH2-CG2 4.07Å; W426-I460 HydrophobicContact CZ2-CG2 4.38Å; W438-I460 HydrophobicContact CH2-CD1 4.13Å; W438-I460 HydrophobicContact CH2-CG2 3.98Å; W438-I460 HydrophobicContact CZ3-CD1 4.4Å; W438-I460 HydrophobicContact CZ3-CG2 4.33Å; T444-I460 HydrophobicContact CG2-CD1 4.3Å; T444-I460 HydrophobicContact CG2-CG1 4.16Å; T444-I460 PolarHBondContact O-N 2.93Å; F446-I460 HydrophobicContact CD1-CG2 4.12Å; F446-I460 HydrophobicContact CE1-CG2 3.79Å
461R88.2Confident85.1Confident172 Ų17263.7 Ų63.765%0.64934%0.336SS*.THydrogen-bonded Turntrans-85.4-23.3173.8-60.1174.3-70.5171.51112.4T444 D459T444-R461 HydrophobicContact CG2-CG 3.91Å; T444-R461 PolarHBondContact OG1-NE 3.22Å; D459-R461 PolarHBondContact O-N 2.88Å; D459-R461 WeakPolarHBondContact OD1-CB 3.45Å; D459-R461 VanDerWaalsContact OD1-CG 3.27Å; D459-R461 WeakPolarHBondContact OD1-CG 3.27Å; D459-R461 IonicContact OD1-CZ 3.21Å; D459-R461 PolarHBondContact OD1-N 2.96Å; D459-R461 IonicContact OD1-NE 3.75Å; D459-R461 PolarHBondContact OD1-NE 3.37Å; D459-R461 IonicContact OD1-NH2 3.19Å; D459-R461 IonicContact OD2-CZ 3.51Å; D459-R461 VanDerWaalsContact OD2-CZ 3.31Å; D459-R461 IonicContact OD2-NE 3.91Å; D459-R461 PolarHBondContact OD2-NE 3.06Å; D459-R461 VanDerWaalsContact OD2-NE 3.15Å; D459-R461 IonicContact OD2-NH2 2.92Å; D459-R461 PolarHBondContact OD2-NH2 3.3Å
462T81.2Confident85.1Confident57 Ų5764 Ų6435%0.3534%0.34SS..  trans-80.6127.4-178.952.60000109.6D459 V468D459-T462 HydrophobicContact CB-CG2 4.28Å; D459-T462 PolarHBondContact O-N 2.86Å; D459-T462 PolarHBondContact O-OG1 2.82Å; T462-V468 HydrophobicContact CG2-CG2 4.37Å
463K66.5Low85.1Confident211 Ų21158 Ų5892%0.91731%0.312SS*.  trans-89.814.5174.1-66.9-173.5175.6-1770112.7
464I58.9Low84.8Confident115 Ų11558 Ų5859%0.5931%0.312SS*.  trans-79.7142.5-171.8-57.5171.3000108.4S466I464-S466 VanDerWaalsContact CG2-OG 3.26Å; I464-S466 WeakPolarHBondContact CG2-OG 3.48Å; I464-S466 PolarHBondContact O-N 2.83Å
465T68.1Low84.1Confident155 Ų15562.9 Ų62.995%0.95133%0.334SS*.SBendtrans-76.40.2179.350.60000113.8
466S68.3Low83.1Confident65 Ų6565.9 Ų65.946%0.45536%0.364SS..SBendtrans-121.3144.2179.862.70000109.9I464I464-S466 VanDerWaalsContact CG2-OG 3.26Å; I464-S466 WeakPolarHBondContact CG2-OG 3.48Å; I464-S466 PolarHBondContact O-N 2.83Å
467P73.5Confident82.5Confident52 Ų5266.2 Ų66.234%0.33837%0.368SS..  trans-57.3149.8177.622.7-33.6000112.2T456 E458 S469 V470T456-P467 HydrophobicContact CG2-CB 3.59Å; T456-P467 HydrophobicContact CG2-CG 4.44Å; E458-P467 WeakPolarHBondContact OE1-CA 3.45Å; E458-P467 VanDerWaalsContact OE1-CB 3.25Å; E458-P467 WeakPolarHBondContact OE1-CB 3.18Å; P467-S469 VanDerWaalsContact C-N 3.3Å; P467-S469 PolarHBondContact O-N 3.39Å; P467-V470 HydrophobicContact CB-CG2 3.74Å; P467-V470 HydrophobicContact CG-CG2 3.31Å
468V80.9Confident82.2Confident73 Ų7369.4 Ų69.444%0.44238%0.382SS..SBendtrans-62.9-40.1-179176.30000110.8F457 D459 T462F457-V468 WeakPolarHBondContact O-CB 3.47Å; F457-V468 PolarHBondContact O-N 2.78Å; F457-V468 VanDerWaalsContact O-N 3.11Å; D459-V468 HydrophobicContact CB-CG2 4.01Å; T462-V468 HydrophobicContact CG2-CG2 4.37Å
469S88.2Confident82.2Confident45 Ų4569 Ų6932%0.31538%0.38SS..EExtended strand (participates in β ladder)trans-158.8144.3172.2-63.20000110.2F457 P467F457-S469 PolarHBondContact N-O 3.22Å; F457-S469 PolarHBondContact O-N 2.77Å; P467-S469 VanDerWaalsContact C-N 3.3Å; P467-S469 PolarHBondContact O-N 3.39Å
470V90.7Very high82.2Confident68 Ų6869.2 Ų69.241%0.41238%0.383SS..EExtended strand (participates in β ladder)trans-131.1133.5174.3-176.20000107.7L454 T456 P467L454-V470 HydrophobicContact CB-CG1 4.22Å; L454-V470 HydrophobicContact CD1-CG1 4.13Å; L454-V470 HydrophobicContact CD2-CG1 4.29Å; L454-V470 HydrophobicContact CG-CG1 4.46Å; T456-V470 HydrophobicContact CG2-CG2 3.94Å; P467-V470 HydrophobicContact CB-CG2 3.74Å; P467-V470 HydrophobicContact CG-CG2 3.31Å
471V92.5Very high82.4Confident21 Ų2167.3 Ų67.313%0.12737%0.373CS..EExtended strand (participates in β ladder)trans-131.4142.2178.2-175.80000109L454 L455 A473 W504 L509L454-V471 WeakPolarHBondContact CA-O 3.02Å; L455-V471 PolarHBondContact N-O 3.13Å; L455-V471 PolarHBondContact O-N 3.43Å; V471-A473 PolarHBondContact O-N 3Å; V471-W504 HydrophobicContact CG1-CE3 4.22Å; V471-W504 HydrophobicContact CG1-CH2 3.67Å; V471-W504 HydrophobicContact CG1-CZ3 3.45Å; V471-W504 VanDerWaalsContact CG1-CZ3 3.45Å; V471-L509 HydrophobicContact CG2-CB 3.77Å; V471-L509 HydrophobicContact CG2-CD1 4.26Å; V471-L509 HydrophobicContact CG2-CD2 4.22Å; V471-L509 HydrophobicContact CG2-CG 4.3Å
472T91.4Very high82.8Confident63 Ų6359.4 Ų59.439%0.38734%0.344SS..EExtended strand (participates in β ladder)trans-76.2109169-53.50000108.7C474T472-C474 WeakPolarHBondContact CG2-O 3.11Å
473A89.7Confident83.6Confident1 Ų157.1 Ų57.11%0.00833%0.33CS..  trans-89.6-26.3179.500000112.8G453 L455 V471 V479 T494 K502 W504G453-A473 PolarHBondContact O-N 2.65Å; L455-A473 HydrophobicContact CB-CB 3.91Å; V471-A473 PolarHBondContact O-N 3Å; A473-V479 HydrophobicContact CB-CG2 3.83Å; A473-T494 HydrophobicContact CB-CG2 4.25Å; A473-K502 VanDerWaalsContact O-CD 3.27Å; A473-K502 WeakPolarHBondContact O-CD 3.29Å; A473-K502 WeakPolarHBondContact O-CE 3.29Å; A473-K502 PolarHBondContact O-NZ 2.81Å; A473-W504 HydrophobicContact CB-CZ2 3.7Å
474C86.6Confident85Confident2 Ų247.5 Ų47.51%0.01429%0.29CS..SBendtrans-140.4134.6172.8-170.50000109G453 T472 V479 A496 E500G453-C474 PolarHBondContact O-N 2.91Å; G453-C474 VanDerWaalsContact O-N 3.09Å; T472-C474 WeakPolarHBondContact CG2-O 3.11Å; C474-V479 HydrophobicContact CB-CG2 3.8Å; C474-A496 HydrophobicContact CB-CB 3.82Å; C474-E500 PolarHBondContact SG-OE2 2.98Å
475H79.1Confident86.7Confident144 Ų14442.1 Ų42.167%0.66726%0.262SS*.SBendtrans-91.8128.4174.4-70.3-73.3000109.1G477H475-G477 PolarHBondContact O-N 2.56Å
476G73.6Confident87.9Confident62 Ų6237 Ų3764%0.63923%0.232SC*.SBendtrans69.711.5176.600000115.3Y498G476-Y498 PolarHBondContact O-OH 2.94Å
477G81.8Confident89Confident9 Ų937.7 Ų37.79%0.09323%0.233CC..SBendtrans-141.8169.8-17800000112.4G453 H475 S497G453-G477 WeakPolarHBondContact CA-O 3.32Å; G453-G477 PolarHBondContact N-O 2.77Å; H475-G477 PolarHBondContact O-N 2.56Å; G477-S497 WeakPolarHBondContact CA-OG 3.09Å
478K87.7Confident89.9Confident80 Ų8036.7 Ų36.735%0.34823%0.225SC..  trans-96.4144.1179.858.9178.5-178.7-175.70111.3D451 A496 S497D451-K478 HydrophobicContact CB-CB 4.25Å; D451-K478 WeakPolarHBondContact OD1-CB 2.98Å; D451-K478 WeakPolarHBondContact OD1-CD 3.4Å; K478-A496 CarbonylContact O-C 3.56Å; K478-A496 WeakPolarHBondContact O-CA 2.98Å; K478-S497 PolarHBondContact N-OG 3.39Å; K478-S497 PolarHBondContact O-N 3.19Å; K478-S497 PolarHBondContact O-OG 3.2Å
479V94.3Very high90.4Very high0 Ų034.4 Ų34.40%021%0.212CC..EExtended strand (participates in β ladder)trans-96.9114.5172.8-178.90000108.5N434 V449 N450 A473 C474 T494 A496N434-V479 WeakPolarHBondContact CB-O 3.41Å; N434-V479 PolarHBondContact ND2-O 2.04Å; V449-V479 HydrophobicContact CB-CB 3.88Å; V449-V479 HydrophobicContact CB-CG1 3.56Å; V449-V479 HydrophobicContact CG1-CB 4.19Å; V449-V479 HydrophobicContact CG1-CG1 3.48Å; V449-V479 VanDerWaalsContact CG1-CG1 3.48Å; V449-V479 HydrophobicContact CG2-CB 4.5Å; V449-V479 HydrophobicContact CG2-CG1 3.96Å; N450-V479 PolarHBondContact O-N 2.99Å; A473-V479 HydrophobicContact CB-CG2 3.83Å; C474-V479 HydrophobicContact CB-CG2 3.8Å; V479-T494 HydrophobicContact CG1-CG2 4.15Å; V479-A496 HydrophobicContact CG2-CB 4.11Å
480S92.9Very high90.6Very high18 Ų1836.9 Ų36.913%0.12622%0.215CC..EExtended strand (participates in β ladder)trans-91.2-29.6-168-64.40000113.3G495 I523S480-G495 PolarHBondContact N-O 2.98Å; S480-I523 WeakPolarHBondContact CB-O 3.45Å
481S95.7Very high90.8Very high1 Ų135.9 Ų35.91%0.00721%0.206CC..EExtended strand (participates in β ladder)trans-142.8149-17659.70000113.2T494 G495 I523S481-T494 WeakPolarHBondContact O-CA 3.21Å; S481-G495 PolarHBondContact N-O 2.81Å; S481-G495 PolarHBondContact O-N 3.14Å; S481-I523 PolarHBondContact OG-O 2.75Å
482V97.4Very high91Very high5 Ų534.9 Ų34.93%0.0320%0.2CC..EExtended strand (participates in β ladder)trans-137.1132.8176.9640000111.3D435 C437 A447 V449 L455 V492 L493D435-V482 HydrophobicContact CB-CG1 4.1Å; D435-V482 PolarHBondContact OD2-N 3.48Å; C437-V482 HydrophobicContact CB-CG1 3.99Å; A447-V482 HydrophobicContact CB-CG2 4.18Å; V449-V482 HydrophobicContact CG1-CB 3.81Å; V449-V482 HydrophobicContact CG1-CG1 4.37Å; V449-V482 HydrophobicContact CG1-CG2 4.23Å; V449-V482 HydrophobicContact CG2-CB 4Å; V449-V482 HydrophobicContact CG2-CG1 4.02Å; L455-V482 HydrophobicContact CD1-CG2 3.94Å; V482-V492 HydrophobicContact CG2-CG1 3.7Å; V482-L493 WeakPolarHBondContact CA-O 3.49Å
483A97.1Very high91.2Very high9 Ų932 Ų327%0.07418%0.182CC..EExtended strand (participates in β ladder)trans-135.7112.1-179.100000112.1L493 L526 W528A483-L493 HydrophobicContact CB-CB 4.43Å; A483-L493 PolarHBondContact N-O 3.03Å; A483-L493 PolarHBondContact O-N 2.96Å; A483-L526 HydrophobicContact CB-CB 4.26Å; A483-W528 PolarHBondContact O-NE1 3.46Å
484C96.6Very high91.6Very high10 Ų1032 Ų327%0.06818%0.181CC..EExtended strand (participates in β ladder)trans-74.9138.1170.8-65.80000110.6C437 W438C437-C484 VanDerWaalsContact SG-CB 3.56Å; C437-C484 PolarHBondContact SG-N 2.89Å; C437-C484 VanDerWaalsContact SG-SG 3.68Å; W438-C484 WeakPolarHBondContact O-CB 3.36Å
485N95.8Very high92Very high1 Ų131.9 Ų31.91%0.00518%0.181CC..  trans-64133.4178-171.6-70.1000110.8T487 N488 F491 W528 E533N485-T487 VanDerWaalsContact C-N 3.33Å; N485-T487 PolarHBondContact O-N 2.91Å; N485-T487 PolarHBondContact OD1-N 3.13Å; N485-T487 PolarHBondContact OD1-OG1 3.18Å; N485-N488 HydrophobicContact CB-CB 4.27Å; N485-N488 WeakPolarHBondContact CB-O 3.5Å; N485-N488 PolarHBondContact OD1-N 2.89Å; N485-F491 HydrophobicContact CB-CB 3.93Å; N485-F491 VanDerWaalsContact CB-O 3.32Å; N485-F491 WeakPolarHBondContact CB-O 3.43Å; N485-F491 PolarHBondContact N-O 3.08Å; N485-W528 HydrophobicContact CB-CD2 4.25Å; N485-W528 HydrophobicContact CB-CZ2 4.02Å; N485-W528 WeakPolarHBondContact ND2-CZ3 3.49Å; N485-E533 PolarHBondContact ND2-O 3.22Å
486P93Very high92.6Very high49 Ų4925 Ų2532%0.31815%0.149SC..SBendtrans-72.7-24.4-175.227.1-34.7000113.6W528P486-W528 HydrophobicContact CG-CB 4.14Å
487T91Very high92.9Very high78 Ų7822.3 Ų22.348%0.47912%0.12SC..SBendtrans-109.8-22.1-174.447.10000113.8N485N485-T487 VanDerWaalsContact C-N 3.33Å; N485-T487 PolarHBondContact O-N 2.91Å; N485-T487 PolarHBondContact OD1-N 3.13Å; N485-T487 PolarHBondContact OD1-OG1 3.18Å
488N92.1Very high92.5Very high31 Ų3124.4 Ų24.417%0.16613%0.126CC..  trans-120.6123.3-175.7-168.4-38.1000109.9N485 Y490 F491 E533N485-N488 HydrophobicContact CB-CB 4.27Å; N485-N488 WeakPolarHBondContact CB-O 3.5Å; N485-N488 PolarHBondContact OD1-N 2.89Å; N488-Y490 PolarHBondContact O-N 2.79Å; N488-Y490 WeakPolarHBondContact OD1-CD2 3.34Å; N488-Y490 PolarHBondContact OD1-N 3.03Å; N488-F491 HydrophobicContact CB-CD2 4.03Å; N488-F491 VanDerWaalsContact ND2-CD2 3.35Å; N488-F491 WeakPolarHBondContact ND2-CD2 3.47Å; N488-F491 VanDerWaalsContact ND2-CE2 3.27Å; N488-F491 WeakPolarHBondContact ND2-CE2 3.23Å; N488-E533 PolarHBondContact ND2-OE1 2.91Å
489S91.6Very high92Very high25 Ų2520.6 Ų20.618%0.17511%0.109CC..THydrogen-bonded Turntrans-70.6-13-17754.70000114.2N439N439-S489 PolarHBondContact ND2-O 3.43Å
490Y92.7Very high91.7Very high97 Ų9722.4 Ų22.438%0.3812%0.118SC..THydrogen-bonded Turntrans-103.5-15.1-168.7-53.1-59.7000114.1N488 D505 T506 R507N488-Y490 PolarHBondContact O-N 2.79Å; N488-Y490 WeakPolarHBondContact OD1-CD2 3.34Å; N488-Y490 PolarHBondContact OD1-N 3.03Å; Y490-D505 CarbonylContact O-C 3.49Å; Y490-D505 VanDerWaalsContact O-CA 3.29Å; Y490-D505 WeakPolarHBondContact O-CA 3.17Å; Y490-T506 WeakPolarHBondContact CA-OG1 3.24Å; Y490-T506 PolarHBondContact O-N 2.77Å; Y490-R507 HydrophobicContact CD1-CG 3.51Å; Y490-R507 HydrophobicContact CE1-CG 3.85Å; Y490-R507 HydrophobicContact CG-CG 4.13Å
491F94.3Very high91.6Very high48 Ų4821.7 Ų21.721%0.21111%0.112CC..EExtended strand (participates in β ladder)trans-102.6129.3-174.7-67-44.7000112.7N485 N488 L503 W504 D505 W528N485-F491 HydrophobicContact CB-CB 3.93Å; N485-F491 VanDerWaalsContact CB-O 3.32Å; N485-F491 WeakPolarHBondContact CB-O 3.43Å; N485-F491 PolarHBondContact N-O 3.08Å; N488-F491 HydrophobicContact CB-CD2 4.03Å; N488-F491 VanDerWaalsContact ND2-CD2 3.35Å; N488-F491 WeakPolarHBondContact ND2-CD2 3.47Å; N488-F491 VanDerWaalsContact ND2-CE2 3.27Å; N488-F491 WeakPolarHBondContact ND2-CE2 3.23Å; F491-L503 HydrophobicContact CB-CD1 4.01Å; F491-L503 HydrophobicContact CD1-CD1 4.1Å; F491-L503 HydrophobicContact CD1-CG 4.49Å; F491-L503 HydrophobicContact CG-CD1 4.23Å; F491-W504 WeakPolarHBondContact CA-O 3.44Å; F491-D505 HydrophobicContact CE1-CB 4.48Å; F491-W528 HydrophobicContact CB-CH2 4.5Å; F491-W528 HydrophobicContact CB-CZ2 4.2Å
492V96.2Very high91.5Very high0 Ų022.4 Ų22.40%012%0.115CC..EExtended strand (participates in β ladder)trans-131.3136.81771770000108.5L455 F457 V482 W504 T506L455-V492 HydrophobicContact CD1-CG1 4.5Å; F457-V492 HydrophobicContact CE1-CG2 3.81Å; F457-V492 HydrophobicContact CZ-CB 4.49Å; F457-V492 HydrophobicContact CZ-CG2 4.21Å; V482-V492 HydrophobicContact CG2-CG1 3.7Å; V492-W504 HydrophobicContact CB-CB 4.4Å; V492-W504 PolarHBondContact N-O 3.23Å; V492-W504 VanDerWaalsContact N-O 3.1Å; V492-W504 PolarHBondContact O-N 3.21Å; V492-T506 HydrophobicContact CG2-CG2 3.86Å
493L96.4Very high91.3Very high1 Ų122.7 Ų22.71%0.00512%0.117CC..EExtended strand (participates in β ladder)trans-102144.5170.8-65.2166.5000110.4V482 A483 I501 K502 L503 L526 W528 L536V482-L493 WeakPolarHBondContact CA-O 3.49Å; A483-L493 HydrophobicContact CB-CB 4.43Å; A483-L493 PolarHBondContact N-O 3.03Å; A483-L493 PolarHBondContact O-N 2.96Å; L493-I501 HydrophobicContact CD2-CG2 4.24Å; L493-K502 CarbonylContact C-O 3.49Å; L493-K502 VanDerWaalsContact CA-O 3.3Å; L493-K502 WeakPolarHBondContact CA-O 3.38Å; L493-L503 HydrophobicContact CD2-CB 4.11Å; L493-L503 HydrophobicContact CD2-CD1 3.89Å; L493-L526 HydrophobicContact CB-CD1 4.05Å; L493-W528 HydrophobicContact CD1-CD2 3.76Å; L493-W528 HydrophobicContact CD1-CE3 4.21Å; L493-W528 HydrophobicContact CD1-CG 4.35Å; L493-W528 HydrophobicContact CD1-CH2 3.98Å; L493-W528 HydrophobicContact CD1-CZ2 3.52Å; L493-W528 HydrophobicContact CD1-CZ3 4.29Å; L493-W528 HydrophobicContact CD2-CH2 4.12Å; L493-W528 HydrophobicContact CD2-CZ2 3.92Å; L493-W528 HydrophobicContact CG-CD2 4.47Å; L493-W528 HydrophobicContact CG-CH2 3.97Å; L493-W528 HydrophobicContact CG-CZ2 3.33Å; L493-L536 HydrophobicContact CD1-CB 3.73Å; L493-L536 HydrophobicContact CD1-CD1 4.37Å; L493-L536 HydrophobicContact CD1-CD2 3.66Å; L493-L536 HydrophobicContact CD1-CG 4.12Å; L493-L536 HydrophobicContact CD2-CD2 3.88Å; L493-L536 HydrophobicContact CG-CD2 4.44Å
494T97.2Very high91.2Very high1 Ų122.4 Ų22.41%0.00611%0.114CC..EExtended strand (participates in β ladder)trans-122137.8164.953.30000109.6V449 L455 A473 V479 S481 I501 K502 W504 L526V449-T494 HydrophobicContact CG1-CG2 4.12Å; L455-T494 HydrophobicContact CB-CG2 4.32Å; L455-T494 HydrophobicContact CD1-CG2 3.93Å; L455-T494 HydrophobicContact CD2-CG2 3.78Å; L455-T494 HydrophobicContact CG-CG2 4.22Å; A473-T494 HydrophobicContact CB-CG2 4.25Å; V479-T494 HydrophobicContact CG1-CG2 4.15Å; S481-T494 WeakPolarHBondContact O-CA 3.21Å; T494-I501 WeakPolarHBondContact O-CA 3.28Å; T494-K502 PolarHBondContact N-O 2.96Å; T494-K502 PolarHBondContact O-N 2.92Å; T494-W504 PolarHBondContact OG1-NE1 3.26Å; T494-L526 VanDerWaalsContact C-CD1 3.43Å
495G94.8Very high91.1Very high0 Ų022.9 Ų22.90%012%0.116CC..EExtended strand (participates in β ladder)trans-115.9116.1172.500000107.8S480 S481 L526S480-G495 PolarHBondContact N-O 2.98Å; S481-G495 PolarHBondContact N-O 2.81Å; S481-G495 PolarHBondContact O-N 3.14Å; G495-L526 VanDerWaalsContact CA-CD1 3.43Å
496A92.3Very high90.9Very high1 Ų124.9 Ų24.91%0.00813%0.128CC..EExtended strand (participates in β ladder)trans-99.4176.9-177.300000111.9C474 K478 V479 E500 I523C474-A496 HydrophobicContact CB-CB 3.82Å; K478-A496 CarbonylContact O-C 3.56Å; K478-A496 WeakPolarHBondContact O-CA 2.98Å; V479-A496 HydrophobicContact CG2-CB 4.11Å; A496-E500 HydrophobicContact CB-CB 4.26Å; A496-E500 PolarHBondContact N-O 3.42Å; A496-I523 PolarHBondContact O-N 3.12Å
497S80.2Confident90.8Very high4 Ų430.2 Ų30.23%0.02814%0.142CC..SBendtrans-51165.6149.850.70000109.1G477 K478 G499 D522G477-S497 WeakPolarHBondContact CA-OG 3.09Å; K478-S497 PolarHBondContact N-OG 3.39Å; K478-S497 PolarHBondContact O-N 3.19Å; K478-S497 PolarHBondContact O-OG 3.2Å; S497-G499 VanDerWaalsContact C-N 3.29Å; S497-G499 PolarHBondContact O-N 3.47Å; S497-D522 VanDerWaalsContact CA-OD1 3.23Å; S497-D522 WeakPolarHBondContact CA-OD1 3.45Å; S497-D522 WeakPolarHBondContact CB-OD1 3.47Å
498Y73.5Confident90.7Very high53 Ų5332 Ų3221%0.20814%0.143CC..THydrogen-bonded Turntrans71.421.9166.3-52.6-26.1000115.2E27 G476 E500 G519 D522E27-Y498 HydrophobicContact CB-CD1 3.13Å; E27-Y498 HydrophobicContact CB-CD2 3.74Å; E27-Y498 HydrophobicContact CB-CE1 3.48Å; E27-Y498 VanDerWaalsContact CB-CE1 3.48Å; E27-Y498 HydrophobicContact CB-CE2 4.03Å; E27-Y498 HydrophobicContact CB-CG 3.28Å; E27-Y498 HydrophobicContact CG-CD1 3.2Å; E27-Y498 HydrophobicContact CG-CD2 4.39Å; E27-Y498 HydrophobicContact CG-CE1 3.97Å; E27-Y498 HydrophobicContact CG-CG 3.47Å; E27-Y498 VanDerWaalsContact CG-CG 3.47Å; E27-Y498 WeakPolarHBondContact O-CE1 3.29Å; E27-Y498 PolarHBondContact O-OH 3.16Å; E27-Y498 WeakPolarHBondContact OE1-CA 3.29Å; E27-Y498 VanDerWaalsContact OE1-CB 3.31Å; E27-Y498 WeakPolarHBondContact OE1-CB 3.42Å; E27-Y498 VanDerWaalsContact OE2-CB 3.25Å; E27-Y498 WeakPolarHBondContact OE2-CB 3.27Å; G476-Y498 PolarHBondContact O-OH 2.94Å; Y498-E500 PolarHBondContact O-N 3Å; Y498-G519 CarbonylContact C-O 3.58Å; Y498-G519 VanDerWaalsContact C-O 3.28Å; Y498-D522 PolarHBondContact N-OD1 3.05Å; Y498-D522 VanDerWaalsContact N-OD1 3.12Å
499G77.5Confident90.5Very high0 Ų031.7 Ų31.70%014%0.141CC..THydrogen-bonded Turntrans65.94.6176.700000116.7S497 I501 L518 G519 R521S497-G499 VanDerWaalsContact C-N 3.29Å; S497-G499 PolarHBondContact O-N 3.47Å; G499-I501 PolarHBondContact O-N 2.78Å; G499-L518 WeakPolarHBondContact O-CB 3.14Å; G499-L518 PolarHBondContact O-N 3.05Å; G499-L518 VanDerWaalsContact O-N 3.12Å; G499-G519 WeakPolarHBondContact CA-O 2.98Å; G499-G519 PolarHBondContact N-O 3Å; G499-R521 WeakPolarHBondContact CA-O 3.35Å; G499-R521 PolarHBondContact N-O 3.16Å
500E87Confident90.1Very high38 Ų3838.8 Ų38.818%0.17817%0.172CC..EExtended strand (participates in β ladder)trans-74.3115.5179.9-61.8-168.4120.200110.7C474 A496 Y498 K502C474-E500 PolarHBondContact SG-OE2 2.98Å; A496-E500 HydrophobicContact CB-CB 4.26Å; A496-E500 PolarHBondContact N-O 3.42Å; Y498-E500 PolarHBondContact O-N 3Å; E500-K502 VanDerWaalsContact CD-CE 3.48Å; E500-K502 WeakPolarHBondContact OE1-CE 3.26Å; E500-K502 IonicContact OE1-NZ 3.77Å; E500-K502 PolarHBondContact OE1-NZ 3.23Å; E500-K502 WeakPolarHBondContact OE2-CE 3.18Å; E500-K502 IonicContact OE2-NZ 2.68Å; E500-K502 PolarHBondContact OE2-NZ 2.9Å
501I92.3Very high89.6Confident3 Ų339.7 Ų39.72%0.01518%0.179CC..EExtended strand (participates in β ladder)trans-106110.9163.4-57.2176000108.1L493 T494 G499 W515 I516 L518 I523 L526 L536 A538 Y548L493-I501 HydrophobicContact CD2-CG2 4.24Å; T494-I501 WeakPolarHBondContact O-CA 3.28Å; G499-I501 PolarHBondContact O-N 2.78Å; I501-W515 CarbonylContact O-C 3.59Å; I501-W515 WeakPolarHBondContact O-CA 3.18Å; I501-I516 HydrophobicContact CB-CB 4.34Å; I501-I516 PolarHBondContact N-O 2.93Å; I501-I516 PolarHBondContact O-N 2Å; I501-L518 HydrophobicContact CD1-CD1 3.53Å; I501-L518 HydrophobicContact CD1-CG 4.47Å; I501-L518 HydrophobicContact CG1-CD1 4.11Å; I501-I523 HydrophobicContact CG1-CD1 4.47Å; I501-I523 HydrophobicContact CG1-CG1 4.03Å; I501-I523 HydrophobicContact CG1-CG2 4.41Å; I501-L526 HydrophobicContact CD1-CD2 4.01Å; I501-L526 HydrophobicContact CG1-CD2 4.29Å; I501-L526 HydrophobicContact CG2-CD1 4.47Å; I501-L526 HydrophobicContact CG2-CD2 4.24Å; I501-L536 HydrophobicContact CD1-CD1 4.43Å; I501-L536 HydrophobicContact CG2-CD1 4.48Å; I501-A538 HydrophobicContact CD1-CB 3.55Å; I501-Y548 HydrophobicContact CD1-CD2 4.47Å; I501-Y548 HydrophobicContact CD1-CE2 4Å
502K93Very high89.2Confident16 Ų1640.8 Ų40.87%0.0719%0.185CC..EExtended strand (participates in β ladder)trans-107138.6179.2-58.6-170.8177.6152.80111.9A473 L493 T494 E500 W504 E512 W515A473-K502 VanDerWaalsContact O-CD 3.27Å; A473-K502 WeakPolarHBondContact O-CD 3.29Å; A473-K502 WeakPolarHBondContact O-CE 3.29Å; A473-K502 PolarHBondContact O-NZ 2.81Å; L493-K502 CarbonylContact C-O 3.49Å; L493-K502 VanDerWaalsContact CA-O 3.3Å; L493-K502 WeakPolarHBondContact CA-O 3.38Å; T494-K502 PolarHBondContact N-O 2.96Å; T494-K502 PolarHBondContact O-N 2.92Å; E500-K502 VanDerWaalsContact CD-CE 3.48Å; E500-K502 WeakPolarHBondContact OE1-CE 3.26Å; E500-K502 IonicContact OE1-NZ 3.77Å; E500-K502 PolarHBondContact OE1-NZ 3.23Å; E500-K502 WeakPolarHBondContact OE2-CE 3.18Å; E500-K502 IonicContact OE2-NZ 2.68Å; E500-K502 PolarHBondContact OE2-NZ 2.9Å; K502-W504 HydrophobicContact CB-CZ2 4.02Å; K502-W504 HydrophobicContact CD-CZ2 3.85Å; K502-E512 HydrophobicContact CB-CB 4.4Å; K502-E512 HydrophobicContact CD-CG 4.44Å; K502-W515 HydrophobicContact CB-CB 4.38Å; K502-W515 HydrophobicContact CG-CB 3.76Å
503L93.8Very high88.7Confident11 Ų1144.5 Ų44.56%0.05821%0.208CC..EExtended strand (participates in β ladder)trans-103.9122.7173.9175.964.4000109.7F491 L493 V513 H514 W528 V550F491-L503 HydrophobicContact CB-CD1 4.01Å; F491-L503 HydrophobicContact CD1-CD1 4.1Å; F491-L503 HydrophobicContact CD1-CG 4.49Å; F491-L503 HydrophobicContact CG-CD1 4.23Å; L493-L503 HydrophobicContact CD2-CB 4.11Å; L493-L503 HydrophobicContact CD2-CD1 3.89Å; L503-V513 HydrophobicContact CD2-CB 4.22Å; L503-V513 HydrophobicContact CD2-CG1 4.16Å; L503-V513 HydrophobicContact CG-CB 4.14Å; L503-V513 WeakPolarHBondContact O-CB 3.34Å; L503-V513 PolarHBondContact O-N 2.82Å; L503-H514 HydrophobicContact CB-CB 4.37Å; L503-H514 WeakPolarHBondContact CB-O 3.12Å; L503-H514 HydrophobicContact CD2-CB 4.43Å; L503-H514 PolarHBondContact N-O 3.23Å; L503-W528 HydrophobicContact CD1-CH2 3.83Å; L503-W528 HydrophobicContact CD1-CZ2 3.96Å; L503-V550 HydrophobicContact CD2-CB 4.45Å; L503-V550 HydrophobicContact CD2-CG2 4.2Å
504W94.7Very high88.3Confident3 Ų345.7 Ų45.71%0.01121%0.213CC..EExtended strand (participates in β ladder)trans-110.4140-178.1-57.490.1000111.3L455 V471 A473 F491 V492 T494 K502 E512L455-W504 HydrophobicContact CD2-CB 4.44Å; L455-W504 HydrophobicContact CD2-CD2 4.02Å; L455-W504 HydrophobicContact CD2-CG 3.78Å; V471-W504 HydrophobicContact CG1-CE3 4.22Å; V471-W504 HydrophobicContact CG1-CH2 3.67Å; V471-W504 HydrophobicContact CG1-CZ3 3.45Å; V471-W504 VanDerWaalsContact CG1-CZ3 3.45Å; A473-W504 HydrophobicContact CB-CZ2 3.7Å; F491-W504 WeakPolarHBondContact CA-O 3.44Å; V492-W504 HydrophobicContact CB-CB 4.4Å; V492-W504 PolarHBondContact N-O 3.23Å; V492-W504 VanDerWaalsContact N-O 3.1Å; V492-W504 PolarHBondContact O-N 3.21Å; T494-W504 PolarHBondContact OG1-NE1 3.26Å; K502-W504 HydrophobicContact CB-CZ2 4.02Å; K502-W504 HydrophobicContact CD-CZ2 3.85Å; W504-E512 HydrophobicContact CD2-CB 4.37Å; W504-E512 HydrophobicContact CE3-CB 4.15Å; W504-E512 HydrophobicContact CH2-CB 4.1Å; W504-E512 HydrophobicContact CZ2-CB 4.3Å; W504-E512 HydrophobicContact CZ3-CB 4.01Å
505D93.3Very high87.7Confident20 Ų2050.9 Ų50.911%0.10723%0.233CC..EExtended strand (participates in β ladder)trans-100.7114.3165.2-173.1-28.2000108.8Y490 F491 R507 K508 V513Y490-D505 CarbonylContact O-C 3.49Å; Y490-D505 VanDerWaalsContact O-CA 3.29Å; Y490-D505 WeakPolarHBondContact O-CA 3.17Å; F491-D505 HydrophobicContact CE1-CB 4.48Å; D505-R507 PolarHBondContact O-N 3.47Å; D505-R507 VanDerWaalsContact OD1-CB 3.22Å; D505-R507 WeakPolarHBondContact OD1-CB 3.5Å; D505-R507 WeakPolarHBondContact OD1-CG 3.43Å; D505-R507 IonicContact OD1-CZ 2.93Å; D505-R507 PolarHBondContact OD1-N 3.21Å; D505-R507 IonicContact OD1-NE 3.15Å; D505-R507 PolarHBondContact OD1-NE 2.77Å; D505-R507 IonicContact OD1-NH2 3.31Å; D505-R507 IonicContact OD2-CZ 3.53Å; D505-R507 IonicContact OD2-NE 2.98Å; D505-R507 PolarHBondContact OD2-NE 2.97Å; D505-R507 IonicContact OD2-NH2 3.9Å; D505-R507 PolarHBondContact OD2-NH2 2.9Å; D505-K508 CarbonylContact O-C 3.55Å; D505-K508 VanDerWaalsContact O-C 3.22Å; D505-K508 PolarHBondContact O-N 3.31Å; D505-V513 HydrophobicContact CB-CG2 3.49Å; D505-V513 VanDerWaalsContact CB-CG2 3.49Å
506T92.2Very high87.3Confident44 Ų4451.2 Ų51.227%0.2723%0.234SC..THydrogen-bonded Turntrans-62.3-10.4-177.966.70000113.7F457 Y490 V492F457-T506 HydrophobicContact CD1-CG2 4.43Å; F457-T506 HydrophobicContact CE1-CG2 3.73Å; F457-T506 HydrophobicContact CZ-CG2 4.08Å; Y490-T506 WeakPolarHBondContact CA-OG1 3.24Å; Y490-T506 PolarHBondContact O-N 2.77Å; V492-T506 HydrophobicContact CG2-CG2 3.86Å
507R90.7Very high86.7Confident161 Ų16154.8 Ų54.861%0.60825%0.254SS*.THydrogen-bonded Turntrans-88.1-23.4175-54.9170.4-67.2177.14.4112.6Y490 D505Y490-R507 HydrophobicContact CD1-CG 3.51Å; Y490-R507 HydrophobicContact CE1-CG 3.85Å; Y490-R507 HydrophobicContact CG-CG 4.13Å; D505-R507 PolarHBondContact O-N 3.47Å; D505-R507 VanDerWaalsContact OD1-CB 3.22Å; D505-R507 WeakPolarHBondContact OD1-CB 3.5Å; D505-R507 WeakPolarHBondContact OD1-CG 3.43Å; D505-R507 IonicContact OD1-CZ 2.93Å; D505-R507 PolarHBondContact OD1-N 3.21Å; D505-R507 IonicContact OD1-NE 3.15Å; D505-R507 PolarHBondContact OD1-NE 2.77Å; D505-R507 IonicContact OD1-NH2 3.31Å; D505-R507 IonicContact OD2-CZ 3.53Å; D505-R507 IonicContact OD2-NE 2.98Å; D505-R507 PolarHBondContact OD2-NE 2.97Å; D505-R507 IonicContact OD2-NH2 3.9Å; D505-R507 PolarHBondContact OD2-NH2 2.9Å
508K88.3Confident86.2Confident114 Ų11455.5 Ų55.550%0.49626%0.257SS..  trans-136.580.2-179.9-170.1-162.8172.7-1540109.3D505 Q510 E511D505-K508 CarbonylContact O-C 3.55Å; D505-K508 VanDerWaalsContact O-C 3.22Å; D505-K508 PolarHBondContact O-N 3.31Å; K508-Q510 VanDerWaalsContact C-N 3.3Å; K508-Q510 PolarHBondContact O-N 3.26Å; K508-E511 IonicContact NZ-OE2 3.33Å; K508-E511 PolarHBondContact NZ-OE2 3.29Å
509L89.2Confident85.7Confident26 Ų2654.3 Ų54.314%0.13626%0.261CS..THydrogen-bonded Turntrans-84.85.1-177-73.8178.8000114.9F457 V471 E511F457-L509 HydrophobicContact CD2-CD1 3.8Å; F457-L509 HydrophobicContact CD2-CD2 4.42Å; F457-L509 HydrophobicContact CE2-CD1 3.83Å; F457-L509 HydrophobicContact CE2-CD2 3.6Å; F457-L509 HydrophobicContact CE2-CG 4.39Å; F457-L509 HydrophobicContact CZ-CD2 4.01Å; V471-L509 HydrophobicContact CG2-CB 3.77Å; V471-L509 HydrophobicContact CG2-CD1 4.26Å; V471-L509 HydrophobicContact CG2-CD2 4.22Å; V471-L509 HydrophobicContact CG2-CG 4.3Å; L509-E511 VanDerWaalsContact C-N 3.31Å
510Q82.2Confident84.8Confident174 Ų17457.2 Ų57.281%0.81327%0.272SS*.THydrogen-bonded Turntrans-72.8-26.9179.7-62.9-62.5-39.200112.5K508K508-Q510 VanDerWaalsContact C-N 3.3Å; K508-Q510 PolarHBondContact O-N 3.26Å
511E82.1Confident84.1Confident115 Ų11557.1 Ų57.154%0.53727%0.27SS..SBendtrans-147148.8-179.2-66.5171.5152.700108.3K508 L509K508-E511 IonicContact NZ-OE2 3.33Å; K508-E511 PolarHBondContact NZ-OE2 3.29Å; L509-E511 VanDerWaalsContact C-N 3.31Å
512E85.6Confident83.6Confident71 Ų7158.8 Ų58.833%0.33228%0.278SS..  trans-64.6146.8167.469.3-75178.500111.4K502 W504 W515K502-E512 HydrophobicContact CB-CB 4.4Å; K502-E512 HydrophobicContact CD-CG 4.44Å; W504-E512 HydrophobicContact CD2-CB 4.37Å; W504-E512 HydrophobicContact CE3-CB 4.15Å; W504-E512 HydrophobicContact CH2-CB 4.1Å; W504-E512 HydrophobicContact CZ2-CB 4.3Å; W504-E512 HydrophobicContact CZ3-CB 4.01Å; E512-W515 HydrophobicContact CG-CB 4.34Å
513V86.7Confident83.5Confident79 Ų7958 Ų5848%0.47928%0.275SS..SBendtrans-70-40.6176.5179.40000110.4L503 D505L503-V513 HydrophobicContact CD2-CB 4.22Å; L503-V513 HydrophobicContact CD2-CG1 4.16Å; L503-V513 HydrophobicContact CG-CB 4.14Å; L503-V513 WeakPolarHBondContact O-CB 3.34Å; L503-V513 PolarHBondContact O-N 2.82Å; D505-V513 HydrophobicContact CB-CG2 3.49Å; D505-V513 VanDerWaalsContact CB-CG2 3.49Å
514H86.7Confident83.3Confident26 Ų2661.3 Ų61.312%0.1229%0.287CS..EExtended strand (participates in β ladder)trans-163.4155.5-176.2-175.763.9000108.6L503 E567L503-H514 HydrophobicContact CB-CB 4.37Å; L503-H514 WeakPolarHBondContact CB-O 3.12Å; L503-H514 HydrophobicContact CD2-CB 4.43Å; L503-H514 PolarHBondContact N-O 3.23Å; H514-E567 IonicContact CE1-OE1 3.28Å; H514-E567 PolarHBondContact CE1-OE1 3.36Å; H514-E567 IonicContact NE2-OE1 2.98Å; H514-E567 PolarHBondContact NE2-OE1 3.11Å
515W85.6Confident83.3Confident110 Ų11061.4 Ų61.442%0.41729%0.288SS..EExtended strand (participates in β ladder)trans-144.1149.6171.766.6-84.4000110I501 K502 E512 D517I501-W515 CarbonylContact O-C 3.59Å; I501-W515 WeakPolarHBondContact O-CA 3.18Å; K502-W515 HydrophobicContact CB-CB 4.38Å; K502-W515 HydrophobicContact CG-CB 3.76Å; E512-W515 HydrophobicContact CG-CB 4.34Å; W515-D517 HydrophobicContact CE3-CB 4.07Å; W515-D517 HydrophobicContact CH2-CB 4.04Å; W515-D517 HydrophobicContact CZ3-CB 3.38Å
516I86.2Confident83.4Confident6 Ų661.2 Ų61.23%0.03129%0.287CS..EExtended strand (participates in β ladder)trans-115123.7176.5-57.8170.3000106.4I501 L518 Y548 I565 E567I501-I516 HydrophobicContact CB-CB 4.34Å; I501-I516 PolarHBondContact N-O 2.93Å; I501-I516 PolarHBondContact O-N 2Å; I516-L518 HydrophobicContact CG2-CD2 3.69Å; I516-L518 HydrophobicContact CG2-CG 4.2Å; I516-Y548 HydrophobicContact CD1-CD1 3.91Å; I516-Y548 HydrophobicContact CD1-CG 3.88Å; I516-Y548 HydrophobicContact CG2-CD1 4.41Å; I516-Y548 HydrophobicContact CG2-CE1 4.15Å; I516-I565 HydrophobicContact CG2-CD1 4.41Å; I516-I565 HydrophobicContact CG2-CG2 4.01Å; I516-E567 HydrophobicContact CD1-CB 4.21Å
517D79.5Confident83.6Confident77 Ų7760 Ų6041%0.41228%0.282SS..EExtended strand (participates in β ladder)trans-88.4124.3169.9-159.8-22.9000109.6W515 G519 I565W515-D517 HydrophobicContact CE3-CB 4.07Å; W515-D517 HydrophobicContact CH2-CB 4.04Å; W515-D517 HydrophobicContact CZ3-CB 3.38Å; D517-G519 WeakPolarHBondContact OD1-CA 3.48Å; D517-G519 PolarHBondContact OD1-N 2.77Å; D517-I565 VanDerWaalsContact O-CD1 3.32Å; D517-I565 WeakPolarHBondContact O-CD1 3.23Å
518L70.1Confident83.9Confident18 Ų1853 Ų539%0.09426%0.256CS..  trans-1066.3174-58.5179.3000112.8G499 I501 I516 R521 I523 Y548 I565G499-L518 WeakPolarHBondContact O-CB 3.14Å; G499-L518 PolarHBondContact O-N 3.05Å; G499-L518 VanDerWaalsContact O-N 3.12Å; I501-L518 HydrophobicContact CD1-CD1 3.53Å; I501-L518 HydrophobicContact CD1-CG 4.47Å; I501-L518 HydrophobicContact CG1-CD1 4.11Å; I516-L518 HydrophobicContact CG2-CD2 3.69Å; I516-L518 HydrophobicContact CG2-CG 4.2Å; L518-R521 HydrophobicContact CB-CB 4.5Å; L518-R521 WeakPolarHBondContact O-CD 3.48Å; L518-I523 HydrophobicContact CD1-CD1 3.63Å; L518-Y548 HydrophobicContact CD1-CE2 4.31Å; L518-Y548 VanDerWaalsContact CD1-OH 3.23Å; L518-Y548 WeakPolarHBondContact CD1-OH 3.33Å; L518-Y548 HydrophobicContact CD2-CE1 3.85Å; L518-Y548 WeakPolarHBondContact CD2-OH 3.18Å; L518-I565 HydrophobicContact CD2-CD1 3.76Å
519G62.6Low84.2Confident28 Ų2847.7 Ų47.729%0.28923%0.233SC..SBendtrans61.3-152.3-166.300000110.8Y498 G499 D517 R521Y498-G519 CarbonylContact C-O 3.58Å; Y498-G519 VanDerWaalsContact C-O 3.28Å; G499-G519 WeakPolarHBondContact CA-O 2.98Å; G499-G519 PolarHBondContact N-O 3Å; D517-G519 WeakPolarHBondContact OD1-CA 3.48Å; D517-G519 PolarHBondContact OD1-N 2.77Å; G519-R521 VanDerWaalsContact C-N 3.26Å; G519-R521 PolarHBondContact O-N 3.06Å
520R60Low84.4Confident62 Ų6248.9 Ų48.923%0.23424%0.242CC..SBendtrans-74.466-168.3-58.8-169.1-168.7162.8-6116V25 E26 E27 R66V25-R520 PolarHBondContact O-NH1 2.83Å; V25-R520 PolarHBondContact O-NH2 2.86Å; E26-R520 VanDerWaalsContact CA-CZ 3.4Å; E26-R520 VanDerWaalsContact CA-NH2 3.26Å; E26-R520 IonicContact OE1-CZ 2.83Å; E26-R520 IonicContact OE1-NE 2.93Å; E26-R520 IonicContact OE1-NH2 3.82Å; E26-R520 PolarHBondContact OE1-NH2 3.04Å; E27-R520 HydrophobicContact CG-CG 3.95Å; E27-R520 WeakPolarHBondContact OE1-CA 3.26Å; E27-R520 PolarHBondContact OE1-N 3.25Å; R66-R520 VanDerWaalsContact CB-NH1 3.28Å
521R71.6Confident84.8Confident35 Ų3542.8 Ų42.813%0.13222%0.221CC..  trans-133.7103.5-175.5-69.4179.5174.3-161.9-6.8108.9G499 L518 G519 I523 D540 T541 D542 E544G499-R521 WeakPolarHBondContact CA-O 3.35Å; G499-R521 PolarHBondContact N-O 3.16Å; L518-R521 HydrophobicContact CB-CB 4.5Å; L518-R521 WeakPolarHBondContact O-CD 3.48Å; G519-R521 VanDerWaalsContact C-N 3.26Å; G519-R521 PolarHBondContact O-N 3.06Å; R521-I523 WeakPolarHBondContact O-CD1 3.05Å; R521-I523 PolarHBondContact O-N 3.22Å; R521-D540 HydrophobicContact CB-CB 4.05Å; R521-D540 IonicContact NH1-OD2 3.81Å; R521-T541 WeakPolarHBondContact CA-OG1 3.4Å; R521-D542 IonicContact CZ-OD2 3.7Å; R521-D542 IonicContact NE-OD2 3.29Å; R521-D542 PolarHBondContact NE-OD2 2.95Å; R521-D542 IonicContact NH2-OD2 3.95Å; R521-D542 PolarHBondContact NH2-OD2 2.88Å; R521-E544 IonicContact CZ-OE2 2.63Å; R521-E544 IonicContact NH1-OE2 3.7Å; R521-E544 PolarHBondContact NH1-OE2 2.92Å; R521-E544 IonicContact NH2-OE1 2.77Å; R521-E544 IonicContact NH2-OE2 3.44Å; R521-E544 PolarHBondContact NH2-OE2 3.29Å; R521-E544 VanDerWaalsContact NH2-OE2 3.17Å
522D82.5Confident85.3Confident38 Ų3842.8 Ų42.820%0.20322%0.219CC..  trans-64.7131177.5-69.8-7.9000109.8S497 Y498 Y524 D540 T541S497-D522 VanDerWaalsContact CA-OD1 3.23Å; S497-D522 WeakPolarHBondContact CA-OD1 3.45Å; S497-D522 WeakPolarHBondContact CB-OD1 3.47Å; Y498-D522 PolarHBondContact N-OD1 3.05Å; Y498-D522 VanDerWaalsContact N-OD1 3.12Å; D522-Y524 HydrophobicContact CB-CE1 4.1Å; D522-Y524 PolarHBondContact O-N 3.28Å; D522-D540 WeakPolarHBondContact O-CA 3.27Å; D522-T541 HydrophobicContact CB-CG2 3.72Å; D522-T541 PolarHBondContact N-OG1 3.47Å; D522-T541 PolarHBondContact O-N 2.71Å
523I90.3Very high85.5Confident0 Ų042.8 Ų42.80%022%0.219CC..EExtended strand (participates in β ladder)trans-9493.2-177.6-51.9-56000109.7S480 S481 A496 I501 L518 R521 L526 A538 D540S480-I523 WeakPolarHBondContact CB-O 3.45Å; S481-I523 PolarHBondContact OG-O 2.75Å; A496-I523 PolarHBondContact O-N 3.12Å; I501-I523 HydrophobicContact CG1-CD1 4.47Å; I501-I523 HydrophobicContact CG1-CG1 4.03Å; I501-I523 HydrophobicContact CG1-CG2 4.41Å; L518-I523 HydrophobicContact CD1-CD1 3.63Å; R521-I523 WeakPolarHBondContact O-CD1 3.05Å; R521-I523 PolarHBondContact O-N 3.22Å; I523-L526 HydrophobicContact CG2-CD1 4.35Å; I523-L526 HydrophobicContact CG2-CD2 3.79Å; I523-L526 HydrophobicContact CG2-CG 3.77Å; I523-A538 HydrophobicContact CG2-CB 4.23Å; I523-D540 HydrophobicContact CD1-CB 3.88Å
524Y89.3Confident85.6Confident80 Ų8039.3 Ų39.331%0.31420%0.199SC..EExtended strand (participates in β ladder)trans-73.7-28.5-178.8-66.7-45.1000113.9D522 G539 T541 E578D522-Y524 HydrophobicContact CB-CE1 4.1Å; D522-Y524 PolarHBondContact O-N 3.28Å; Y524-G539 PolarHBondContact N-O 2.92Å; Y524-T541 HydrophobicContact CD2-CG2 4.34Å; Y524-T541 HydrophobicContact CE2-CG2 3.47Å; Y524-T541 VanDerWaalsContact CE2-CG2 3.47Å; Y524-T541 WeakPolarHBondContact OH-CG2 3.48Å; Y524-E578 HydrophobicContact CE2-CB 4.26Å; Y524-E578 HydrophobicContact CE2-CG 4.45Å
525T94.5Very high86Confident5 Ų538.2 Ų38.23%0.03119%0.194CC..EExtended strand (participates in β ladder)trans-148.6139.8-175.6-1700000112.6A538 G539 I579 D581 I582T525-A538 WeakPolarHBondContact O-CA 3.41Å; T525-G539 PolarHBondContact O-N 2.98Å; T525-I579 HydrophobicContact CG2-CG2 4.09Å; T525-D581 PolarHBondContact OG1-OD1 2.88Å; T525-I582 HydrophobicContact CG2-CB 4.3Å; T525-I582 HydrophobicContact CG2-CD1 4.2Å; T525-I582 HydrophobicContact CG2-CG1 3.79Å; T525-I582 HydrophobicContact CG2-CG2 3.94Å
526L95.4Very high86.5Confident16 Ų1633 Ų338%0.08417%0.174CC..EExtended strand (participates in β ladder)trans-132140.3178.6-74.4173.8000110.3A483 L493 T494 G495 I501 I523 L536 A537 A538A483-L526 HydrophobicContact CB-CB 4.26Å; L493-L526 HydrophobicContact CB-CD1 4.05Å; T494-L526 VanDerWaalsContact C-CD1 3.43Å; G495-L526 VanDerWaalsContact CA-CD1 3.43Å; I501-L526 HydrophobicContact CD1-CD2 4.01Å; I501-L526 HydrophobicContact CG1-CD2 4.29Å; I501-L526 HydrophobicContact CG2-CD1 4.47Å; I501-L526 HydrophobicContact CG2-CD2 4.24Å; I523-L526 HydrophobicContact CG2-CD1 4.35Å; I523-L526 HydrophobicContact CG2-CD2 3.79Å; I523-L526 HydrophobicContact CG2-CG 3.77Å; L526-L536 HydrophobicContact CD2-CD1 4.19Å; L526-A537 WeakPolarHBondContact CA-O 3.43Å; L526-A538 HydrophobicContact CD2-CB 3.63Å
527A96.5Very high86.9Confident19 Ų1932.7 Ų32.716%0.15717%0.173CC..EExtended strand (participates in β ladder)trans-149.1127.1174.200000112.5A537 I582 W584A527-A537 PolarHBondContact N-O 2.88Å; A527-A537 PolarHBondContact O-N 3.38Å; A527-I582 HydrophobicContact CB-CD1 3.9Å; A527-I582 HydrophobicContact CB-CG1 3.96Å; A527-W584 PolarHBondContact O-NE1 3.49Å
528W96.8Very high87.7Confident15 Ų1529 Ų296%0.05715%0.153CC..EExtended strand (participates in β ladder)trans-65.6137.6169.7-69.9101.5000111.4A483 N485 P486 F491 L493 L503 P530 E533 L536A483-W528 PolarHBondContact O-NE1 3.46Å; N485-W528 HydrophobicContact CB-CD2 4.25Å; N485-W528 HydrophobicContact CB-CZ2 4.02Å; N485-W528 WeakPolarHBondContact ND2-CZ3 3.49Å; P486-W528 HydrophobicContact CG-CB 4.14Å; F491-W528 HydrophobicContact CB-CH2 4.5Å; F491-W528 HydrophobicContact CB-CZ2 4.2Å; L493-W528 HydrophobicContact CD1-CD2 3.76Å; L493-W528 HydrophobicContact CD1-CE3 4.21Å; L493-W528 HydrophobicContact CD1-CG 4.35Å; L493-W528 HydrophobicContact CD1-CH2 3.98Å; L493-W528 HydrophobicContact CD1-CZ2 3.52Å; L493-W528 HydrophobicContact CD1-CZ3 4.29Å; L493-W528 HydrophobicContact CD2-CH2 4.12Å; L493-W528 HydrophobicContact CD2-CZ2 3.92Å; L493-W528 HydrophobicContact CG-CD2 4.47Å; L493-W528 HydrophobicContact CG-CH2 3.97Å; L493-W528 HydrophobicContact CG-CZ2 3.33Å; L503-W528 HydrophobicContact CD1-CH2 3.83Å; L503-W528 HydrophobicContact CD1-CZ2 3.96Å; W528-P530 VanDerWaalsContact O-CD 3.3Å; W528-P530 WeakPolarHBondContact O-CD 3.36Å; W528-E533 VanDerWaalsContact CZ3-O 3.24Å; W528-E533 WeakPolarHBondContact CZ3-O 3.31Å; W528-L536 HydrophobicContact CE3-CB 4.25Å
529C95.8Very high88.7Confident2 Ų228.1 Ų28.11%0.01415%0.149CC..  trans-69.9119.7172.8-1740000110.1A531 K532 V535 W584C529-A531 PolarHBondContact O-N 2.94Å; C529-A531 VanDerWaalsContact O-N 3.17Å; C529-K532 CarbonylContact O-C 3.48Å; C529-K532 PolarHBondContact O-N 3.05Å; C529-K532 VanDerWaalsContact O-O 3.07Å; C529-V535 HydrophobicContact CB-CB 3.71Å; C529-V535 HydrophobicContact CB-CG1 3.73Å; C529-V535 VanDerWaalsContact CB-O 3.28Å; C529-V535 WeakPolarHBondContact CB-O 2.99Å; C529-V535 PolarHBondContact N-O 2.88Å; C529-W584 HydrophobicContact CB-CD2 4.47Å; C529-W584 HydrophobicContact CB-CH2 4.41Å; C529-W584 HydrophobicContact CB-CZ2 4.01Å
530P93Very high89.8Confident51 Ų5126.8 Ų26.833%0.33114%0.135SC..THydrogen-bonded Turntrans-64.6-22.3179.4-22.533.9000113.8W528 W584 K586W528-P530 VanDerWaalsContact O-CD 3.3Å; W528-P530 WeakPolarHBondContact O-CD 3.36Å; P530-W584 HydrophobicContact CG-CB 3.73Å; P530-W584 HydrophobicContact CG-CG 4.41Å; P530-K586 HydrophobicContact CG-CG 4.33Å
531A90.2Very high90.7Very high46 Ų4625.7 Ų25.738%0.3814%0.135SC..THydrogen-bonded Turntrans-86.3-18.7-176.800000113.6C529 P589C529-A531 PolarHBondContact O-N 2.94Å; C529-A531 VanDerWaalsContact O-N 3.17Å; A531-P589 HydrophobicContact CB-CB 4.01Å
532K92.8Very high90.6Very high115 Ų11528.1 Ų28.150%0.515%0.151SC..  trans-147.1115.8-174.8-70-65.3-174.6173.30110.5C529 G534 V535 W590C529-K532 CarbonylContact O-C 3.48Å; C529-K532 PolarHBondContact O-N 3.05Å; C529-K532 VanDerWaalsContact O-O 3.07Å; K532-G534 VanDerWaalsContact C-N 3.3Å; K532-G534 PolarHBondContact O-N 2.83Å; K532-V535 HydrophobicContact CB-CB 3.92Å; K532-V535 HydrophobicContact CB-CG2 3.61Å; K532-V535 HydrophobicContact CG-CG2 4.31Å; K532-V535 PolarHBondContact O-N 3.48Å; K532-V535 VanDerWaalsContact O-N 3.1Å; K532-W590 HydrophobicContact CG-CH2 4.27Å; K532-W590 HydrophobicContact CG-CZ2 3.71Å
533E89.2Confident90.1Very high71 Ų7126.8 Ų26.833%0.33215%0.145SC..THydrogen-bonded Turntrans-53.1-38.5-175.1-178.6-167.4-163.200114.8N485 N488 W528 K551N485-E533 PolarHBondContact ND2-O 3.22Å; N488-E533 PolarHBondContact ND2-OE1 2.91Å; W528-E533 VanDerWaalsContact CZ3-O 3.24Å; W528-E533 WeakPolarHBondContact CZ3-O 3.31Å; E533-K551 IonicContact OE2-NZ 3.75Å; E533-K551 PolarHBondContact OE2-NZ 3Å; E533-K551 VanDerWaalsContact OE2-NZ 3.16Å
534G89.5Confident89.7Confident5 Ų527.7 Ų27.75%0.05215%0.149CC..THydrogen-bonded Turntrans-90.7-1.2-176.500000114.8K532 D549 V550K532-G534 VanDerWaalsContact C-N 3.3Å; K532-G534 PolarHBondContact O-N 2.83Å; G534-D549 WeakPolarHBondContact O-CA 3.35Å; G534-V550 WeakPolarHBondContact O-CG2 3.41Å; G534-V550 PolarHBondContact O-N 3.49Å
535V94.9Very high89.7Confident3 Ų323.9 Ų23.92%0.01814%0.135CC..EExtended strand (participates in β ladder)trans-99.6134.1-174.9177.70000109.8C529 K532 I547 Y548 D549 L569 W590C529-V535 HydrophobicContact CB-CB 3.71Å; C529-V535 HydrophobicContact CB-CG1 3.73Å; C529-V535 VanDerWaalsContact CB-O 3.28Å; C529-V535 WeakPolarHBondContact CB-O 2.99Å; C529-V535 PolarHBondContact N-O 2.88Å; K532-V535 HydrophobicContact CB-CB 3.92Å; K532-V535 HydrophobicContact CB-CG2 3.61Å; K532-V535 HydrophobicContact CG-CG2 4.31Å; K532-V535 PolarHBondContact O-N 3.48Å; K532-V535 VanDerWaalsContact O-N 3.1Å; V535-I547 HydrophobicContact CG1-CG2 3.57Å; V535-Y548 CarbonylContact C-O 3.57Å; V535-Y548 VanDerWaalsContact CA-O 3.25Å; V535-Y548 WeakPolarHBondContact CA-O 3.25Å; V535-D549 HydrophobicContact CG2-CB 4.12Å; V535-L569 HydrophobicContact CG1-CD1 4.34Å; V535-L569 HydrophobicContact CG2-CD1 4.17Å; V535-W590 HydrophobicContact CG1-CH2 4.17Å; V535-W590 HydrophobicContact CG1-CZ3 3.97Å; V535-W590 HydrophobicContact CG2-CH2 4.11Å
536L94.9Very high89.6Confident0 Ų023.7 Ų23.70%013%0.133CC..EExtended strand (participates in β ladder)trans-132.7157.3175.970.499.3000110.5L493 I501 L526 W528 I547 Y548 V550L493-L536 HydrophobicContact CD1-CB 3.73Å; L493-L536 HydrophobicContact CD1-CD1 4.37Å; L493-L536 HydrophobicContact CD1-CD2 3.66Å; L493-L536 HydrophobicContact CD1-CG 4.12Å; L493-L536 HydrophobicContact CD2-CD2 3.88Å; L493-L536 HydrophobicContact CG-CD2 4.44Å; I501-L536 HydrophobicContact CD1-CD1 4.43Å; I501-L536 HydrophobicContact CG2-CD1 4.48Å; L526-L536 HydrophobicContact CD2-CD1 4.19Å; W528-L536 HydrophobicContact CE3-CB 4.25Å; L536-I547 CarbonylContact O-C 3.58Å; L536-I547 WeakPolarHBondContact O-CA 3.11Å; L536-Y548 HydrophobicContact CD1-CD2 3.67Å; L536-Y548 HydrophobicContact CD1-CG 4.43Å; L536-Y548 HydrophobicContact CG-CD2 4.36Å; L536-Y548 PolarHBondContact N-O 2.71Å; L536-Y548 PolarHBondContact O-N 3.26Å; L536-V550 HydrophobicContact CD2-CG1 3.62Å
537A96.1Very high89.5Confident0 Ų023.7 Ų23.70%013%0.133CC..EExtended strand (participates in β ladder)trans-118.6144.4167.400000110L526 A527 V545 T546 I547 I582 W584 M592L526-A537 WeakPolarHBondContact CA-O 3.43Å; A527-A537 PolarHBondContact N-O 2.88Å; A527-A537 PolarHBondContact O-N 3.38Å; A537-V545 HydrophobicContact CB-CG1 4.47Å; A537-T546 CarbonylContact C-O 3.57Å; A537-T546 VanDerWaalsContact CA-O 3.3Å; A537-T546 WeakPolarHBondContact CA-O 3.48Å; A537-I547 HydrophobicContact CB-CG1 4.36Å; A537-I582 HydrophobicContact CB-CD1 3.77Å; A537-I582 WeakPolarHBondContact O-CD1 3.22Å; A537-W584 HydrophobicContact CB-CZ2 3.63Å; A537-M592 HydrophobicContact CB-CE 4.23Å; A537-M592 HydrophobicContact CB-SD 3.67Å
538A94.8Very high89.3Confident0 Ų022.8 Ų22.80%013%0.126CC..EExtended strand (participates in β ladder)trans-124.5138.5174.100000109.9I501 I523 T525 L526 V545 T546 Y548I501-A538 HydrophobicContact CD1-CB 3.55Å; I523-A538 HydrophobicContact CG2-CB 4.23Å; T525-A538 WeakPolarHBondContact O-CA 3.41Å; L526-A538 HydrophobicContact CD2-CB 3.63Å; A538-V545 CarbonylContact O-C 3.47Å; A538-V545 WeakPolarHBondContact O-CA 2.91Å; A538-T546 PolarHBondContact N-O 2.99Å; A538-T546 PolarHBondContact O-N 2.68Å; A538-Y548 HydrophobicContact CB-CE2 4.03Å
539G92Very high89Confident0 Ų023.4 Ų23.40%013%0.13CC..EExtended strand (participates in β ladder)trans-110.6130.1169.200000110.1Y524 T525Y524-G539 PolarHBondContact N-O 2.92Å; T525-G539 PolarHBondContact O-N 2.98Å
540D85.4Confident88.5Confident0 Ų024.2 Ų24.20%014%0.135CC..EExtended strand (participates in β ladder)trans-124.5179.9-172.466.235.9000114.2R521 D522 I523 D542 E544 I579R521-D540 HydrophobicContact CB-CB 4.05Å; R521-D540 IonicContact NH1-OD2 3.81Å; D522-D540 WeakPolarHBondContact O-CA 3.27Å; I523-D540 HydrophobicContact CD1-CB 3.88Å; D540-D542 VanDerWaalsContact C-N 3.32Å; D540-D542 PolarHBondContact O-N 2.96Å; D540-D542 PolarHBondContact OD1-N 3.26Å; D540-E544 PolarHBondContact N-O 2.83Å; D540-E544 PolarHBondContact OD1-N 3.34Å; D540-I579 PolarHBondContact O-N 3.31Å; D540-I579 VanDerWaalsContact O-N 3.11Å
541T78.6Confident87.9Confident38 Ų3827.2 Ų27.223%0.23314%0.143CC..THydrogen-bonded Turntrans-69.2-22.2178.847.80000114.6R521 D522 Y524 A543R521-T541 WeakPolarHBondContact CA-OG1 3.4Å; D522-T541 HydrophobicContact CB-CG2 3.72Å; D522-T541 PolarHBondContact N-OG1 3.47Å; D522-T541 PolarHBondContact O-N 2.71Å; Y524-T541 HydrophobicContact CD2-CG2 4.34Å; Y524-T541 HydrophobicContact CE2-CG2 3.47Å; Y524-T541 VanDerWaalsContact CE2-CG2 3.47Å; Y524-T541 WeakPolarHBondContact OH-CG2 3.48Å; T541-A543 PolarHBondContact O-N 2.87Å; T541-A543 VanDerWaalsContact O-N 3.16Å
542D70.1Confident87Confident87 Ų8728.3 Ų28.347%0.46514%0.141SC..THydrogen-bonded Turntrans-81.511.7-176.3-91.2-1.1000112.8R521 D540 E544R521-D542 IonicContact CZ-OD2 3.7Å; R521-D542 IonicContact NE-OD2 3.29Å; R521-D542 PolarHBondContact NE-OD2 2.95Å; R521-D542 IonicContact NH2-OD2 3.95Å; R521-D542 PolarHBondContact NH2-OD2 2.88Å; D540-D542 VanDerWaalsContact C-N 3.32Å; D540-D542 PolarHBondContact O-N 2.96Å; D540-D542 PolarHBondContact OD1-N 3.26Å; D542-E544 HydrophobicContact CB-CG 4.21Å; D542-E544 PolarHBondContact O-N 2.97Å
543A71.9Confident85.6Confident10 Ų1024.1 Ų24.18%0.08313%0.126CC..SBendtrans60.732.2-171.400000112.4T541 H575 G577T541-A543 PolarHBondContact O-N 2.87Å; T541-A543 VanDerWaalsContact O-N 3.16Å; A543-H575 HydrophobicContact CB-CB 3.91Å; A543-H575 WeakPolarHBondContact CB-O 3.16Å; A543-H575 WeakPolarHBondContact O-CB 3.3Å; A543-G577 VanDerWaalsContact CA-O 3.24Å; A543-G577 WeakPolarHBondContact CA-O 3.48Å; A543-G577 WeakPolarHBondContact CB-O 3.45Å
544E81.3Confident83.8Confident18 Ų1826 Ų268%0.08415%0.145CC..  trans-110.5137.8177.7-59.1-168.9165.300111.1R521 D540 D542 T571 H572 R573 I579R521-E544 IonicContact CZ-OE2 2.63Å; R521-E544 IonicContact NH1-OE2 3.7Å; R521-E544 PolarHBondContact NH1-OE2 2.92Å; R521-E544 IonicContact NH2-OE1 2.77Å; R521-E544 IonicContact NH2-OE2 3.44Å; R521-E544 PolarHBondContact NH2-OE2 3.29Å; R521-E544 VanDerWaalsContact NH2-OE2 3.17Å; D540-E544 PolarHBondContact N-O 2.83Å; D540-E544 PolarHBondContact OD1-N 3.34Å; D542-E544 HydrophobicContact CB-CG 4.21Å; D542-E544 PolarHBondContact O-N 2.97Å; E544-T571 HydrophobicContact CB-CG2 3.91Å; E544-T571 HydrophobicContact CG-CG2 4.2Å; E544-T571 WeakPolarHBondContact OE2-CG2 3.34Å; E544-H572 WeakPolarHBondContact CA-O 3.4Å; E544-R573 VanDerWaalsContact CD-NE 3.34Å; E544-R573 HydrophobicContact CG-CG 4.06Å; E544-R573 VanDerWaalsContact OE1-CD 3.23Å; E544-R573 WeakPolarHBondContact OE1-CD 3.48Å; E544-R573 WeakPolarHBondContact OE1-CG 3.35Å; E544-R573 IonicContact OE1-CZ 3.24Å; E544-R573 IonicContact OE1-NE 3.41Å; E544-R573 PolarHBondContact OE1-NE 2.74Å; E544-R573 IonicContact OE1-NH2 3.36Å; E544-R573 PolarHBondContact OE1-NH2 3.44Å; E544-R573 IonicContact OE2-CZ 3.66Å; E544-R573 IonicContact OE2-NE 3.43Å; E544-R573 PolarHBondContact OE2-NE 2.62Å; E544-R573 IonicContact OE2-NH2 3.16Å; E544-R573 PolarHBondContact OE2-NH2 3.34Å; E544-I579 WeakPolarHBondContact O-CG1 3.3Å
545V90.6Very high81.8Confident1 Ų131.7 Ų31.71%0.00617%0.173CC..EExtended strand (participates in β ladder)trans-108.4113.8163.3-179.10000107.7A537 A538 H572 I579 I582 M592A537-V545 HydrophobicContact CB-CG1 4.47Å; A538-V545 CarbonylContact O-C 3.47Å; A538-V545 WeakPolarHBondContact O-CA 2.91Å; V545-H572 HydrophobicContact CB-CB 4.2Å; V545-H572 PolarHBondContact N-O 2.76Å; V545-H572 VanDerWaalsContact N-O 3.12Å; V545-H572 PolarHBondContact O-N 2.52Å; V545-I579 HydrophobicContact CG2-CD1 3.87Å; V545-I579 HydrophobicContact CG2-CG1 3.85Å; V545-I579 HydrophobicContact CG2-CG2 4.03Å; V545-I582 HydrophobicContact CG1-CG2 4.37Å; V545-I582 HydrophobicContact CG2-CG2 4.25Å; V545-M592 HydrophobicContact CG1-CE 3.61Å; V545-M592 HydrophobicContact CG1-SD 4.11Å
546T90.9Very high79.1Confident0 Ų041.4 Ų41.40%021%0.21CC..EExtended strand (participates in β ladder)trans-111.6134.4-178.8-56.50000111.4A537 A538 Y548 K568 F570 T571A537-T546 CarbonylContact C-O 3.57Å; A537-T546 VanDerWaalsContact CA-O 3.3Å; A537-T546 WeakPolarHBondContact CA-O 3.48Å; A538-T546 PolarHBondContact N-O 2.99Å; A538-T546 PolarHBondContact O-N 2.68Å; T546-Y548 WeakPolarHBondContact CB-OH 2.87Å; T546-Y548 HydrophobicContact CG2-CD1 4.22Å; T546-Y548 HydrophobicContact CG2-CD2 4.23Å; T546-Y548 HydrophobicContact CG2-CE1 3.52Å; T546-Y548 HydrophobicContact CG2-CE2 3.57Å; T546-Y548 WeakPolarHBondContact CG2-OH 3.11Å; T546-K568 HydrophobicContact CG2-CD 4.08Å; T546-K568 HydrophobicContact CG2-CG 3.76Å; T546-F570 CarbonylContact C-O 3.56Å; T546-F570 WeakPolarHBondContact CA-O 3.46Å; T546-T571 VanDerWaalsContact CG2-OG1 3.26Å; T546-T571 WeakPolarHBondContact CG2-OG1 3.19Å; T546-T571 WeakPolarHBondContact OG1-CG2 3.38Å; T546-T571 PolarHBondContact OG1-OG1 2.58Å; T546-T571 VanDerWaalsContact OG1-OG1 3.08Å
547I93.4Very high76.6Confident17 Ų1750 Ų509%0.08725%0.25CC..EExtended strand (participates in β ladder)trans-101.8128.9176.6-57.2173.6000108.3V535 L536 A537 L569 F570 W584 M592V535-I547 HydrophobicContact CG1-CG2 3.57Å; L536-I547 CarbonylContact O-C 3.58Å; L536-I547 WeakPolarHBondContact O-CA 3.11Å; A537-I547 HydrophobicContact CB-CG1 4.36Å; I547-L569 HydrophobicContact CG2-CB 4.22Å; I547-L569 HydrophobicContact CG2-CD1 4.14Å; I547-L569 PolarHBondContact O-N 2.96Å; I547-F570 HydrophobicContact CB-CB 4.36Å; I547-F570 HydrophobicContact CD1-CB 4.34Å; I547-F570 HydrophobicContact CD1-CD1 4.06Å; I547-F570 PolarHBondContact N-O 3.25Å; I547-F570 PolarHBondContact O-N 2.87Å; I547-W584 HydrophobicContact CD1-CH2 4.02Å; I547-W584 HydrophobicContact CG1-CH2 4.39Å; I547-M592 HydrophobicContact CD1-CE 4.13Å; I547-M592 HydrophobicContact CG1-CE 4.25Å
548Y92.4Very high73.5Confident0 Ų057.5 Ų57.50%029%0.29CS..EExtended strand (participates in β ladder)trans-120.9151178.2-52.2-88.7000110.8I501 I516 L518 V535 L536 A538 T546 E567 K568I501-Y548 HydrophobicContact CD1-CD2 4.47Å; I501-Y548 HydrophobicContact CD1-CE2 4Å; I516-Y548 HydrophobicContact CD1-CD1 3.91Å; I516-Y548 HydrophobicContact CD1-CG 3.88Å; I516-Y548 HydrophobicContact CG2-CD1 4.41Å; I516-Y548 HydrophobicContact CG2-CE1 4.15Å; L518-Y548 HydrophobicContact CD1-CE2 4.31Å; L518-Y548 VanDerWaalsContact CD1-OH 3.23Å; L518-Y548 WeakPolarHBondContact CD1-OH 3.33Å; L518-Y548 HydrophobicContact CD2-CE1 3.85Å; L518-Y548 WeakPolarHBondContact CD2-OH 3.18Å; V535-Y548 CarbonylContact C-O 3.57Å; V535-Y548 VanDerWaalsContact CA-O 3.25Å; V535-Y548 WeakPolarHBondContact CA-O 3.25Å; L536-Y548 HydrophobicContact CD1-CD2 3.67Å; L536-Y548 HydrophobicContact CD1-CG 4.43Å; L536-Y548 HydrophobicContact CG-CD2 4.36Å; L536-Y548 PolarHBondContact N-O 2.71Å; L536-Y548 PolarHBondContact O-N 3.26Å; A538-Y548 HydrophobicContact CB-CE2 4.03Å; T546-Y548 WeakPolarHBondContact CB-OH 2.87Å; T546-Y548 HydrophobicContact CG2-CD1 4.22Å; T546-Y548 HydrophobicContact CG2-CD2 4.23Å; T546-Y548 HydrophobicContact CG2-CE1 3.52Å; T546-Y548 HydrophobicContact CG2-CE2 3.57Å; T546-Y548 WeakPolarHBondContact CG2-OH 3.11Å; Y548-E567 CarbonylContact C-O 3.57Å; Y548-E567 WeakPolarHBondContact CA-O 3.38Å; Y548-E567 HydrophobicContact CD1-CB 4.49Å; Y548-K568 HydrophobicContact CD1-CB 4.23Å; Y548-K568 HydrophobicContact CE1-CB 4.25Å; Y548-K568 HydrophobicContact CE1-CG 4.38Å
549D90.6Very high70.6Confident28 Ų2863.7 Ų63.715%0.1533%0.327CS..EExtended strand (participates in β ladder)trans-118.6106.9165.7-172.1-9.9000109.7G534 V535 K551 M552 E567 L569G534-D549 WeakPolarHBondContact O-CA 3.35Å; V535-D549 HydrophobicContact CG2-CB 4.12Å; D549-K551 PolarHBondContact O-N 2.65Å; D549-K551 VanDerWaalsContact O-N 3.13Å; D549-K551 VanDerWaalsContact OD1-CB 3.3Å; D549-K551 WeakPolarHBondContact OD1-CB 3.48Å; D549-K551 PolarHBondContact OD1-N 3.45Å; D549-M552 HydrophobicContact CB-CG 4.05Å; D549-M552 WeakPolarHBondContact O-CB 3.38Å; D549-M552 PolarHBondContact O-N 3.18Å; D549-M552 VanDerWaalsContact O-N 3.09Å; D549-E567 PolarHBondContact N-O 3.29Å; D549-L569 HydrophobicContact CB-CD1 3.76Å; D549-L569 HydrophobicContact CB-CD2 4.11Å; D549-L569 HydrophobicContact CB-CG 3.87Å
550V86.9Confident68.2Low19 Ų1969.7 Ų69.712%0.11536%0.364CS..G310 helixtrans-67.9-12.5-178.7-57.20000112.4L503 G534 L536 M552 C553L503-V550 HydrophobicContact CD2-CB 4.45Å; L503-V550 HydrophobicContact CD2-CG2 4.2Å; G534-V550 WeakPolarHBondContact O-CG2 3.41Å; G534-V550 PolarHBondContact O-N 3.49Å; L536-V550 HydrophobicContact CD2-CG1 3.62Å; V550-M552 PolarHBondContact O-N 3.28Å; V550-C553 PolarHBondContact O-N 3.24Å; V550-C553 PolarHBondContact O-SG 3.04Å
551K80.5Confident65.8Low114 Ų11476.6 Ų76.650%0.49640%0.401SS..G310 helixtrans-72.5-19.4174.2-63.1-175.4178.9-171.70112.2E533 D549 C553E533-K551 IonicContact OE2-NZ 3.75Å; E533-K551 PolarHBondContact OE2-NZ 3Å; E533-K551 VanDerWaalsContact OE2-NZ 3.16Å; D549-K551 PolarHBondContact O-N 2.65Å; D549-K551 VanDerWaalsContact O-N 3.13Å; D549-K551 VanDerWaalsContact OD1-CB 3.3Å; D549-K551 WeakPolarHBondContact OD1-CB 3.48Å; D549-K551 PolarHBondContact OD1-N 3.45Å; K551-C553 PolarHBondContact O-N 3.25Å
552M69.5Low63.7Low68 Ų6880.9 Ų80.934%0.33542%0.419SS..G310 helixtrans-71.1-18.3177.4-64.4-64.1-177.400112.8D549 V550 C554 I555 L569D549-M552 HydrophobicContact CB-CG 4.05Å; D549-M552 WeakPolarHBondContact O-CB 3.38Å; D549-M552 PolarHBondContact O-N 3.18Å; D549-M552 VanDerWaalsContact O-N 3.09Å; V550-M552 PolarHBondContact O-N 3.28Å; M552-C554 PolarHBondContact O-N 3.18Å; M552-C554 VanDerWaalsContact O-N 3.13Å; M552-I555 PolarHBondContact O-N 3.1Å; M552-I555 VanDerWaalsContact O-N 3.08Å; M552-I555 HydrophobicContact SD-CD1 3.74Å; M552-L569 HydrophobicContact CE-CD2 4.41Å
553C64.4Low62.3Low28 Ų2886.1 Ų86.119%0.18944%0.438CS..G310 helixtrans-61.1-25.1178.277.50000113.2V550 K551 I555 E567V550-C553 PolarHBondContact O-N 3.24Å; V550-C553 PolarHBondContact O-SG 3.04Å; K551-C553 PolarHBondContact O-N 3.25Å; C553-I555 PolarHBondContact O-N 2.79Å; C553-E567 HydrophobicContact CB-CG 4.26Å; C553-E567 WeakPolarHBondContact CB-OE1 3.21Å
554C51.2Low61.1Low109 Ų10988.4 Ų88.474%0.73646%0.462SS*.G310 helixtrans-74.2-10.9179.7-65.20000113.2M552 R556M552-C554 PolarHBondContact O-N 3.18Å; M552-C554 VanDerWaalsContact O-N 3.13Å; C554-R556 PolarHBondContact O-N 2.68Å
555I47Very low59.8Low125 Ų12590.2 Ų90.264%0.64147%0.472SS*.  trans-84.858.6175-48.2176.1000108.3M552 C553M552-I555 PolarHBondContact O-N 3.1Å; M552-I555 VanDerWaalsContact O-N 3.08Å; M552-I555 HydrophobicContact SD-CD1 3.74Å; C553-I555 PolarHBondContact O-N 2.79Å
556R39.2Very low58.4Low208 Ų20896.5 Ų96.579%0.78550%0.5SS*.  trans-102.518-173.7-111.8-171.9-176.8-168.52.5114.7C554C554-R556 PolarHBondContact O-N 2.68Å
557Q41.5Very low57.8Low180 Ų18097.3 Ų97.384%0.84150%0.504SS*.  trans-117.10.4-166.7-75.3-164.9-2100118.3
558N32.1Very low57.3Low157 Ų157100 Ų10084%0.8452%0.516SS*.  trans-124.8107.4175.9-78.5-22.1000113.5
559V33.1Very low57Low130 Ų130103.7 Ų103.779%0.78854%0.535SS*.THydrogen-bonded Turntrans-27.1136.2156.7173.90000113.9
560T41.8Very low56.8Low126 Ų126105.5 Ų105.577%0.77354%0.541SS*.THydrogen-bonded Turntrans98.86.5162.9550000123.4E562T560-E562 PolarHBondContact O-N 2.69Å
561D34.5Very low56.7Low146 Ų146105.9 Ų105.978%0.78154%0.544SS*.  trans-95.2110.8176.2-73.7-20.3000114.4
562E35.9Very low56.8Low128 Ų128101 Ų10160%0.59852%0.523SS*.  trans-46.5133.6168.1-84.9175.6175.100115.3T560T560-E562 PolarHBondContact O-N 2.69Å
563F38.8Very low57Low197 Ų197105.3 Ų105.386%0.86454%0.535SS*.SBendtrans52.786.2152.4-59.9-76.3000119.7
564G47.1Very low57.2Low57 Ų57108 Ų10859%0.58855%0.551SS**SBendtrans166.5149.5157.900000114.8H566G564-H566 PolarHBondContact O-N 2.72Å; G564-H566 VanDerWaalsContact O-N 3.14Å
565I54.8Low58Low57 Ų57104.8 Ų104.829%0.29253%0.525SS..  trans-64109.4166.5-59.1172.5000107.2I516 D517 L518 E567 K568I516-I565 HydrophobicContact CG2-CD1 4.41Å; I516-I565 HydrophobicContact CG2-CG2 4.01Å; D517-I565 VanDerWaalsContact O-CD1 3.32Å; D517-I565 WeakPolarHBondContact O-CD1 3.23Å; L518-I565 HydrophobicContact CD2-CD1 3.76Å; I565-E567 HydrophobicContact CG2-CB 4.32Å; I565-E567 WeakPolarHBondContact CG2-OE2 3.38Å; I565-E567 PolarHBondContact O-N 3.36Å; I565-E567 VanDerWaalsContact O-N 3.12Å; I565-K568 HydrophobicContact CB-CB 4.39Å; I565-K568 WeakPolarHBondContact O-CB 3.19Å; I565-K568 PolarHBondContact O-N 3.47Å
566H60.8Low58.7Low132 Ų132102.9 Ų102.961%0.61152%0.519SS*.THydrogen-bonded Turntrans-61.2-22.8-172.2-65.1-72.2000113.7G564 K568G564-H566 PolarHBondContact O-N 2.72Å; G564-H566 VanDerWaalsContact O-N 3.14Å; H566-K568 VanDerWaalsContact C-N 3.34Å
567E78.3Confident60Low18 Ų1893.6 Ų93.68%0.08449%0.488CS..THydrogen-bonded Turntrans-78.6-16.2179.6-59.678.3-171.700113H514 I516 Y548 D549 C553 I565 L569H514-E567 IonicContact CE1-OE1 3.28Å; H514-E567 PolarHBondContact CE1-OE1 3.36Å; H514-E567 IonicContact NE2-OE1 2.98Å; H514-E567 PolarHBondContact NE2-OE1 3.11Å; I516-E567 HydrophobicContact CD1-CB 4.21Å; Y548-E567 CarbonylContact C-O 3.57Å; Y548-E567 WeakPolarHBondContact CA-O 3.38Å; Y548-E567 HydrophobicContact CD1-CB 4.49Å; D549-E567 PolarHBondContact N-O 3.29Å; C553-E567 HydrophobicContact CB-CG 4.26Å; C553-E567 WeakPolarHBondContact CB-OE1 3.21Å; I565-E567 HydrophobicContact CG2-CB 4.32Å; I565-E567 WeakPolarHBondContact CG2-OE2 3.38Å; I565-E567 PolarHBondContact O-N 3.36Å; I565-E567 VanDerWaalsContact O-N 3.12Å; E567-L569 PolarHBondContact O-N 3.08Å
568K83.9Confident61.8Low74 Ų7489.2 Ų89.232%0.32247%0.468SS..EExtended strand (participates in β ladder)trans-73.6114.5-174.7-173.5176.1-63.2-1710111.3T546 Y548 I565 H566T546-K568 HydrophobicContact CG2-CD 4.08Å; T546-K568 HydrophobicContact CG2-CG 3.76Å; Y548-K568 HydrophobicContact CD1-CB 4.23Å; Y548-K568 HydrophobicContact CE1-CB 4.25Å; Y548-K568 HydrophobicContact CE1-CG 4.38Å; I565-K568 HydrophobicContact CB-CB 4.39Å; I565-K568 WeakPolarHBondContact O-CB 3.19Å; I565-K568 PolarHBondContact O-N 3.47Å; H566-K568 VanDerWaalsContact C-N 3.34Å
569L86Confident64.6Low76 Ų7681.7 Ų81.740%0.39843%0.428SS..EExtended strand (participates in β ladder)trans-87-43.1175.3-68.7-176.3000112.6V535 I547 D549 M552 E567 W590V535-L569 HydrophobicContact CG1-CD1 4.34Å; V535-L569 HydrophobicContact CG2-CD1 4.17Å; I547-L569 HydrophobicContact CG2-CB 4.22Å; I547-L569 HydrophobicContact CG2-CD1 4.14Å; I547-L569 PolarHBondContact O-N 2.96Å; D549-L569 HydrophobicContact CB-CD1 3.76Å; D549-L569 HydrophobicContact CB-CD2 4.11Å; D549-L569 HydrophobicContact CB-CG 3.87Å; M552-L569 HydrophobicContact CE-CD2 4.41Å; E567-L569 PolarHBondContact O-N 3.08Å; L569-W590 HydrophobicContact CD1-CH2 4.42Å
570F85.7Confident67.3Low66 Ų6676.4 Ų76.429%0.28940%0.396SS..EExtended strand (participates in β ladder)trans-162.8140.6-172179.7-101.6000111.6P240 Y241 T546 I547 H572P240-F570 HydrophobicContact CB-CE2 4.21Å; Y241-F570 HydrophobicContact CD1-CZ 4.24Å; Y241-F570 AromaticContact CE1-CE1 3.87Å; Y241-F570 HydrophobicContact CE1-CE1 3.87Å; Y241-F570 AromaticContact CE1-CZ 3.44Å; Y241-F570 HydrophobicContact CE1-CZ 3.44Å; Y241-F570 VanDerWaalsContact CE1-CZ 3.44Å; Y241-F570 AromaticContact CZ-CZ 3.77Å; T546-F570 CarbonylContact C-O 3.56Å; T546-F570 WeakPolarHBondContact CA-O 3.46Å; I547-F570 HydrophobicContact CB-CB 4.36Å; I547-F570 HydrophobicContact CD1-CB 4.34Å; I547-F570 HydrophobicContact CD1-CD1 4.06Å; I547-F570 PolarHBondContact N-O 3.25Å; I547-F570 PolarHBondContact O-N 2.87Å; F570-H572 HydrophobicContact CE1-CB 3.91Å
571T83.8Confident69.8Low28 Ų2870.4 Ų70.417%0.17236%0.359CS..EExtended strand (participates in β ladder)trans-123.2125.5171-60.70000110.7E544 T546 R573E544-T571 HydrophobicContact CB-CG2 3.91Å; E544-T571 HydrophobicContact CG-CG2 4.2Å; E544-T571 WeakPolarHBondContact OE2-CG2 3.34Å; T546-T571 VanDerWaalsContact CG2-OG1 3.26Å; T546-T571 WeakPolarHBondContact CG2-OG1 3.19Å; T546-T571 WeakPolarHBondContact OG1-CG2 3.38Å; T546-T571 PolarHBondContact OG1-OG1 2.58Å; T546-T571 VanDerWaalsContact OG1-OG1 3.08Å; T571-R573 HydrophobicContact CG2-CG 3.61Å
572H82.5Confident72.8Confident12 Ų1263.7 Ų63.76%0.05632%0.323CS..EExtended strand (participates in β ladder)trans-90109.6171.3-177.366.3000110.5Y241 M244 E544 V545 F570 V574 H575Y241-H572 AromaticContact CE1-ND1 3.6Å; Y241-H572 AromaticContact CZ-ND1 3.46Å; Y241-H572 PolarHBondContact OH-CE1 3.41Å; Y241-H572 PolarHBondContact OH-ND1 3.26Å; M244-H572 WeakPolarHBondContact CE-CE1 3.48Å; E544-H572 WeakPolarHBondContact CA-O 3.4Å; V545-H572 HydrophobicContact CB-CB 4.2Å; V545-H572 PolarHBondContact N-O 2.76Å; V545-H572 VanDerWaalsContact N-O 3.12Å; V545-H572 PolarHBondContact O-N 2.52Å; F570-H572 HydrophobicContact CE1-CB 3.91Å; H572-V574 VanDerWaalsContact CE1-CB 3.41Å; H572-V574 WeakPolarHBondContact CE1-CB 3.45Å; H572-V574 WeakPolarHBondContact CE1-CG2 3.41Å; H572-H575 AromaticContact CD2-CD2 3.36Å; H572-H575 PolarHBondContact CD2-CD2 2.94Å; H572-H575 AromaticContact CD2-NE2 3.31Å; H572-H575 PolarHBondContact CD2-NE2 3.31Å; H572-H575 VanDerWaalsContact CD2-NE2 3.31Å; H572-H575 AromaticContact NE2-CD2 3.79Å; H572-H575 AromaticContact NE2-CE1 3.86Å; H572-H575 AromaticContact NE2-NE2 3.58Å
573R74.1Confident75.7Confident157 Ų15758.2 Ų58.259%0.59230%0.299SS*.  trans-110.830.3-176.7-56.3-172.3163.2-179.5-12.4114.1E544 T571E544-R573 VanDerWaalsContact CD-NE 3.34Å; E544-R573 HydrophobicContact CG-CG 4.06Å; E544-R573 VanDerWaalsContact OE1-CD 3.23Å; E544-R573 WeakPolarHBondContact OE1-CD 3.48Å; E544-R573 WeakPolarHBondContact OE1-CG 3.35Å; E544-R573 IonicContact OE1-CZ 3.24Å; E544-R573 IonicContact OE1-NE 3.41Å; E544-R573 PolarHBondContact OE1-NE 2.74Å; E544-R573 IonicContact OE1-NH2 3.36Å; E544-R573 PolarHBondContact OE1-NH2 3.44Å; E544-R573 IonicContact OE2-CZ 3.66Å; E544-R573 IonicContact OE2-NE 3.43Å; E544-R573 PolarHBondContact OE2-NE 2.62Å; E544-R573 IonicContact OE2-NH2 3.16Å; E544-R573 PolarHBondContact OE2-NH2 3.34Å; T571-R573 HydrophobicContact CG2-CG 3.61Å
574V69.5Low78.5Confident86 Ų8649.5 Ų49.552%0.52126%0.261SS..  trans-97.8-15.4-176.1-171.90000111.9H572H572-V574 VanDerWaalsContact CE1-CB 3.41Å; H572-V574 WeakPolarHBondContact CE1-CB 3.45Å; H572-V574 WeakPolarHBondContact CE1-CG2 3.41Å
575H68.4Low80.7Confident41 Ų4147 Ų4719%0.1923%0.234CC..  trans-68.4153.2176.4-64.7-56.3000111.2A543 H572 I579 S594 V596A543-H575 HydrophobicContact CB-CB 3.91Å; A543-H575 WeakPolarHBondContact CB-O 3.16Å; A543-H575 WeakPolarHBondContact O-CB 3.3Å; H572-H575 AromaticContact CD2-CD2 3.36Å; H572-H575 PolarHBondContact CD2-CD2 2.94Å; H572-H575 AromaticContact CD2-NE2 3.31Å; H572-H575 PolarHBondContact CD2-NE2 3.31Å; H572-H575 VanDerWaalsContact CD2-NE2 3.31Å; H572-H575 AromaticContact NE2-CD2 3.79Å; H572-H575 AromaticContact NE2-CE1 3.86Å; H572-H575 AromaticContact NE2-NE2 3.58Å; H575-I579 HydrophobicContact CB-CD1 3.86Å; H575-I579 WeakPolarHBondContact CD2-CD1 3.12Å; H575-S594 PolarHBondContact CE1-OG 2.8Å; H575-S594 WeakPolarHBondContact NE2-CB 3.38Å; H575-S594 PolarHBondContact NE2-OG 2.89Å; H575-V596 HydrophobicContact CB-CG2 3.47Å; H575-V596 VanDerWaalsContact CB-CG2 3.47Å; H575-V596 WeakPolarHBondContact ND1-CG2 3.32Å
576T60Low82.5Confident84 Ų8449.2 Ų49.252%0.51524%0.241SC..SBendtrans-117.817.6-177.259.70000113R822T576-R822 VanDerWaalsContact CG2-NH1 3.33Å
577G67.4Low83.9Confident13 Ų1345.9 Ų45.913%0.13423%0.228CC..SBendtrans-167.7170.2-179.500000109.9A543 V596 I597A543-G577 VanDerWaalsContact CA-O 3.24Å; A543-G577 WeakPolarHBondContact CA-O 3.48Å; A543-G577 WeakPolarHBondContact CB-O 3.45Å; G577-V596 VanDerWaalsContact C-CG1 3.44Å; G577-V596 VanDerWaalsContact CA-CG1 3.48Å; G577-V596 WeakPolarHBondContact O-CG1 3.44Å; G577-I597 CarbonylContact C-O 3.55Å
578E80.1Confident84.5Confident88 Ų8845.9 Ų45.941%0.41123%0.228SC..EExtended strand (participates in β ladder)trans-53.8139.3-176.6-62.5163.4-15800111.8Y524 S580 V596 I597Y524-E578 HydrophobicContact CE2-CB 4.26Å; Y524-E578 HydrophobicContact CE2-CG 4.45Å; E578-S580 PolarHBondContact O-N 3.42Å; E578-V596 CarbonylContact O-C 3.54Å; E578-V596 VanDerWaalsContact O-CA 3.32Å; E578-V596 WeakPolarHBondContact O-CA 3.31Å; E578-I597 HydrophobicContact CB-CG2 4.08Å; E578-I597 PolarHBondContact N-O 2.82Å; E578-I597 VanDerWaalsContact N-O 3.12Å; E578-I597 PolarHBondContact O-N 3.49Å
579I89.3Confident84.8Confident0 Ų045 Ų450%023%0.23CC..EExtended strand (participates in β ladder)trans-78.2117.2176.8-51-52.3000109.2T525 D540 E544 V545 H575 I582 L595 V596T525-I579 HydrophobicContact CG2-CG2 4.09Å; D540-I579 PolarHBondContact O-N 3.31Å; D540-I579 VanDerWaalsContact O-N 3.11Å; E544-I579 WeakPolarHBondContact O-CG1 3.3Å; V545-I579 HydrophobicContact CG2-CD1 3.87Å; V545-I579 HydrophobicContact CG2-CG1 3.85Å; V545-I579 HydrophobicContact CG2-CG2 4.03Å; H575-I579 HydrophobicContact CB-CD1 3.86Å; H575-I579 WeakPolarHBondContact CD2-CD1 3.12Å; I579-I582 HydrophobicContact CG2-CG2 3.77Å; I579-L595 WeakPolarHBondContact CA-O 3.44Å; I579-V596 HydrophobicContact CD1-CG2 3.98Å
580S89.7Confident85Confident18 Ų1847.6 Ų47.613%0.12624%0.235CC..EExtended strand (participates in β ladder)trans-89.5-39.9-177.952.70000113.4A253 E578 L595A253-S580 PolarHBondContact O-OG 3.29Å; E578-S580 PolarHBondContact O-N 3.42Å; S580-L595 PolarHBondContact N-O 2.96Å; S580-L595 WeakPolarHBondContact OG-CG 3.03Å; S580-L595 PolarHBondContact OG-O 2.86Å
581D95.3Very high85.4Confident0 Ų045.7 Ų45.70%023%0.227CC..EExtended strand (participates in β ladder)trans-157152178.3-162.819.5000111.1F254 S255 V256 R326 R328 T525 L595F254-D581 WeakPolarHBondContact O-CB 3.39Å; S255-D581 WeakPolarHBondContact CA-OD2 3.41Å; V256-D581 HydrophobicContact CG1-CB 4.01Å; V256-D581 PolarHBondContact N-OD2 2.79Å; V256-D581 VanDerWaalsContact O-OD2 3.1Å; R326-D581 IonicContact CZ-OD1 3.71Å; R326-D581 IonicContact NH1-OD1 2.76Å; R326-D581 PolarHBondContact NH1-OD1 2.76Å; R326-D581 IonicContact NH1-OD2 2.69Å; R326-D581 PolarHBondContact NH1-OD2 3.4Å; R326-D581 VanDerWaalsContact NH1-OD2 3.09Å; R326-D581 IonicContact NH2-OD1 2.72Å; R328-D581 IonicContact CZ-OD2 3.88Å; R328-D581 IonicContact NH1-OD2 3.96Å; R328-D581 PolarHBondContact NH1-OD2 3.21Å; R328-D581 IonicContact NH2-OD1 2.67Å; R328-D581 PolarHBondContact NH2-OD1 2.83Å; R328-D581 IonicContact NH2-OD2 2.89Å; R328-D581 PolarHBondContact NH2-OD2 3.13Å; T525-D581 PolarHBondContact OG1-OD1 2.88Å; D581-L595 WeakPolarHBondContact O-CB 3.47Å; D581-L595 PolarHBondContact O-N 3.49Å
582I96.6Very high85.9Confident5 Ų546.6 Ų46.63%0.02623%0.23CC..EExtended strand (participates in β ladder)trans-130.7150.2175.562.1177.9000109.9T525 A527 A537 V545 I579 M592 A593T525-I582 HydrophobicContact CG2-CB 4.3Å; T525-I582 HydrophobicContact CG2-CD1 4.2Å; T525-I582 HydrophobicContact CG2-CG1 3.79Å; T525-I582 HydrophobicContact CG2-CG2 3.94Å; A527-I582 HydrophobicContact CB-CD1 3.9Å; A527-I582 HydrophobicContact CB-CG1 3.96Å; A537-I582 HydrophobicContact CB-CD1 3.77Å; A537-I582 WeakPolarHBondContact O-CD1 3.22Å; V545-I582 HydrophobicContact CG1-CG2 4.37Å; V545-I582 HydrophobicContact CG2-CG2 4.25Å; I579-I582 HydrophobicContact CG2-CG2 3.77Å; I582-M592 HydrophobicContact CB-SD 4.41Å; I582-A593 CarbonylContact C-O 3.58Å; I582-A593 WeakPolarHBondContact CA-O 3.31Å
583S97.1Very high86.6Confident13 Ų1346.6 Ų46.69%0.09123%0.232CC..EExtended strand (participates in β ladder)trans-146.8124.1176.3-175.70000111.1Q257 W258 M592 A593Q257-S583 WeakPolarHBondContact CA-OG 3.3Å; W258-S583 PolarHBondContact N-OG 3.03Å; W258-S583 PolarHBondContact NE1-O 3.4Å; S583-M592 CarbonylContact O-C 3.55Å; S583-M592 WeakPolarHBondContact O-CA 3.32Å; S583-A593 PolarHBondContact N-O 2.81Å; S583-A593 PolarHBondContact O-N 2.76Å
584W97.1Very high87.5Confident15 Ų1541 Ų416%0.05722%0.217CC..EExtended strand (participates in β ladder)trans-76.9141167.7-66.6102.5000111.4W258 A527 C529 P530 A537 I547 W590 M592W258-W584 VanDerWaalsContact CD1-C 3.45Å; A527-W584 PolarHBondContact O-NE1 3.49Å; C529-W584 HydrophobicContact CB-CD2 4.47Å; C529-W584 HydrophobicContact CB-CH2 4.41Å; C529-W584 HydrophobicContact CB-CZ2 4.01Å; P530-W584 HydrophobicContact CG-CB 3.73Å; P530-W584 HydrophobicContact CG-CG 4.41Å; A537-W584 HydrophobicContact CB-CZ2 3.63Å; I547-W584 HydrophobicContact CD1-CH2 4.02Å; I547-W584 HydrophobicContact CG1-CH2 4.39Å; W584-W590 HydrophobicContact CH2-CE3 4.46Å; W584-M592 HydrophobicContact CD2-CB 4.3Å; W584-M592 HydrophobicContact CD2-CG 4.43Å; W584-M592 HydrophobicContact CD2-SD 4.27Å; W584-M592 HydrophobicContact CE3-CB 3.85Å; W584-M592 HydrophobicContact CE3-CG 4.46Å; W584-M592 HydrophobicContact CH2-CE 4.27Å; W584-M592 HydrophobicContact CH2-SD 4.27Å; W584-M592 HydrophobicContact CZ2-CE 4.44Å; W584-M592 HydrophobicContact CZ2-SD 4Å; W584-M592 HydrophobicContact CZ3-CB 4.01Å
585D94.5Very high88.6Confident4 Ų437.7 Ų37.72%0.02120%0.196CC..  trans-75.3126.4167.5-166.4-54.4000109.1W258 R279 D587 I588 M591W258-D585 HydrophobicContact CB-CB 4.47Å; W258-D585 HydrophobicContact CD2-CB 4.18Å; W258-D585 HydrophobicContact CG-CB 3.95Å; R279-D585 IonicContact CZ-OD1 3.84Å; R279-D585 IonicContact CZ-OD2 2.83Å; R279-D585 IonicContact NE-OD1 3.92Å; R279-D585 IonicContact NE-OD2 3.77Å; R279-D585 PolarHBondContact NE-OD2 2.85Å; R279-D585 IonicContact NH2-OD1 3.73Å; R279-D585 PolarHBondContact NH2-OD1 3.27Å; R279-D585 IonicContact NH2-OD2 3.65Å; R279-D585 PolarHBondContact NH2-OD2 2.98Å; D585-D587 WeakPolarHBondContact OD1-CA 3.26Å; D585-D587 PolarHBondContact OD1-N 3.15Å; D585-I588 HydrophobicContact CB-CB 4.45Å; D585-I588 PolarHBondContact OD1-N 2.83Å; D585-M591 HydrophobicContact CB-CB 3.79Å; D585-M591 HydrophobicContact CB-CG 4.01Å; D585-M591 PolarHBondContact N-O 2.63Å
586K91.5Very high89.2Confident104 Ų10437.4 Ų37.445%0.45220%0.197SC..SBendtrans-78-17.9179.7-67.5-174.8177.4-1800113.1E390 P530E390-K586 IonicContact OE1-NZ 2.74Å; E390-K586 PolarHBondContact OE1-NZ 3.06Å; E390-K586 IonicContact OE2-NZ 2.81Å; P530-K586 HydrophobicContact CG-CG 4.33Å
587D90.4Very high89.7Confident62 Ų6235.1 Ų35.133%0.33218%0.182SC..SBendtrans-102.6-35-175.7-58.9-59.5000113P260 E261 R279 D585P260-D587 WeakPolarHBondContact CA-OD2 3.38Å; E261-D587 PolarHBondContact N-OD2 3.25Å; R279-D587 IonicContact CZ-OD2 3.82Å; R279-D587 IonicContact NH1-OD2 2.82Å; R279-D587 PolarHBondContact NH1-OD2 2.04Å; R279-D587 IonicContact NH2-OD2 2.81Å; R279-D587 PolarHBondContact NH2-OD2 3.13Å; D585-D587 WeakPolarHBondContact OD1-CA 3.26Å; D585-D587 PolarHBondContact OD1-N 3.15Å
588I91.4Very high89.1Confident17 Ų1736.7 Ų36.79%0.08720%0.198CC..SBendtrans-104.3108.8177.9-55.6177.2000109V277 R279 V297 D585 M591V277-I588 HydrophobicContact CG2-CD1 4.06Å; R279-I588 HydrophobicContact CG-CD1 3.83Å; V297-I588 HydrophobicContact CG2-CD1 3.83Å; D585-I588 HydrophobicContact CB-CB 4.45Å; D585-I588 PolarHBondContact OD1-N 2.83Å; I588-M591 HydrophobicContact CB-CB 3.96Å; I588-M591 HydrophobicContact CG2-CB 3.85Å; I588-M591 HydrophobicContact CG2-CE 4.2Å; I588-M591 WeakPolarHBondContact O-CB 3.45Å; I588-M591 PolarHBondContact O-N 2.96Å
589P89.9Confident87.7Confident55 Ų5535 Ų3536%0.35719%0.193SC..THydrogen-bonded Turntrans-56.2141.8179.9-2534.6000112.1A531 M591A531-P589 HydrophobicContact CB-CB 4.01Å; P589-M591 PolarHBondContact O-N 3.28Å; P589-M591 VanDerWaalsContact O-N 3.07Å
590W91.5Very high85.9Confident131 Ų13140.5 Ų40.550%0.49621%0.214SC..THydrogen-bonded Turntrans63.43.6177.8-57.497.8000116.3K532 V535 L569 W584K532-W590 HydrophobicContact CG-CH2 4.27Å; K532-W590 HydrophobicContact CG-CZ2 3.71Å; V535-W590 HydrophobicContact CG1-CH2 4.17Å; V535-W590 HydrophobicContact CG1-CZ3 3.97Å; V535-W590 HydrophobicContact CG2-CH2 4.11Å; L569-W590 HydrophobicContact CD1-CH2 4.42Å; W584-W590 HydrophobicContact CH2-CE3 4.46Å
591M93.2Very high84.7Confident26 Ų2641.9 Ų41.913%0.12822%0.222CC..  trans-81.9127.9172.8-175.267.959.600110T243 W258 V297 D585 I588 P589T243-M591 HydrophobicContact CG2-CE 3.89Å; T243-M591 HydrophobicContact CG2-SD 4.43Å; W258-M591 HydrophobicContact CZ2-CG 4.1Å; V297-M591 HydrophobicContact CB-CE 4.39Å; D585-M591 HydrophobicContact CB-CB 3.79Å; D585-M591 HydrophobicContact CB-CG 4.01Å; D585-M591 PolarHBondContact N-O 2.63Å; I588-M591 HydrophobicContact CB-CB 3.96Å; I588-M591 HydrophobicContact CG2-CB 3.85Å; I588-M591 HydrophobicContact CG2-CE 4.2Å; I588-M591 WeakPolarHBondContact O-CB 3.45Å; I588-M591 PolarHBondContact O-N 2.96Å; P589-M591 PolarHBondContact O-N 3.28Å; P589-M591 VanDerWaalsContact O-N 3.07Å
592M95.2Very high84.2Confident47 Ų4742.8 Ų42.823%0.23223%0.228CC..EExtended strand (participates in β ladder)trans-134.2144.2179.8-178.2168.34900109.9A537 V545 I547 I582 S583 W584A537-M592 HydrophobicContact CB-CE 4.23Å; A537-M592 HydrophobicContact CB-SD 3.67Å; V545-M592 HydrophobicContact CG1-CE 3.61Å; V545-M592 HydrophobicContact CG1-SD 4.11Å; I547-M592 HydrophobicContact CD1-CE 4.13Å; I547-M592 HydrophobicContact CG1-CE 4.25Å; I582-M592 HydrophobicContact CB-SD 4.41Å; S583-M592 CarbonylContact O-C 3.55Å; S583-M592 WeakPolarHBondContact O-CA 3.32Å; W584-M592 HydrophobicContact CD2-CB 4.3Å; W584-M592 HydrophobicContact CD2-CG 4.43Å; W584-M592 HydrophobicContact CD2-SD 4.27Å; W584-M592 HydrophobicContact CE3-CB 3.85Å; W584-M592 HydrophobicContact CE3-CG 4.46Å; W584-M592 HydrophobicContact CH2-CE 4.27Å; W584-M592 HydrophobicContact CH2-SD 4.27Å; W584-M592 HydrophobicContact CZ2-CE 4.44Å; W584-M592 HydrophobicContact CZ2-SD 4Å; W584-M592 HydrophobicContact CZ3-CB 4.01Å
593A95.3Very high83.7Confident12 Ų1242.5 Ų42.510%0.09923%0.227CC..EExtended strand (participates in β ladder)trans-107.7136.5165.100000108.4V256 W258 L281 I582 S583V256-A593 HydrophobicContact CG2-CB 4.07Å; W258-A593 HydrophobicContact CZ2-CB 4.02Å; L281-A593 HydrophobicContact CD2-CB 3.87Å; I582-A593 CarbonylContact C-O 3.58Å; I582-A593 WeakPolarHBondContact CA-O 3.31Å; S583-A593 PolarHBondContact N-O 2.81Å; S583-A593 PolarHBondContact O-N 2.76Å
594S94.2Very high83Confident40 Ų4044.1 Ų44.128%0.2824%0.236SC..EExtended strand (participates in β ladder)trans-125.3143.2173.5490000109.4H575H575-S594 PolarHBondContact CE1-OG 2.8Å; H575-S594 WeakPolarHBondContact NE2-CB 3.38Å; H575-S594 PolarHBondContact NE2-OG 2.89Å
595L91.6Very high82.4Confident17 Ų1744.2 Ų44.29%0.08924%0.239CC..EExtended strand (participates in β ladder)trans-120141.1-177.3-169.667.7000109.7L249 A253 V256 I579 S580 D581L249-L595 HydrophobicContact CD1-CD1 3.5Å; A253-L595 HydrophobicContact CB-CD1 4.06Å; A253-L595 HydrophobicContact CB-CD2 3.65Å; A253-L595 HydrophobicContact CB-CG 4.31Å; A253-L595 WeakPolarHBondContact O-CD2 3.41Å; A253-L595 WeakPolarHBondContact O-CG 2.99Å; V256-L595 HydrophobicContact CB-CB 4.34Å; V256-L595 HydrophobicContact CB-CD2 4.31Å; V256-L595 HydrophobicContact CG1-CB 4.05Å; I579-L595 WeakPolarHBondContact CA-O 3.44Å; S580-L595 PolarHBondContact N-O 2.96Å; S580-L595 WeakPolarHBondContact OG-CG 3.03Å; S580-L595 PolarHBondContact OG-O 2.86Å; D581-L595 WeakPolarHBondContact O-CB 3.47Å; D581-L595 PolarHBondContact O-N 3.49Å
596V81.2Confident81.4Confident35 Ų3546.9 Ų46.921%0.21226%0.261CS..EExtended strand (participates in β ladder)trans-115137.5179.6173.40000109.4H575 G577 E578 I579H575-V596 HydrophobicContact CB-CG2 3.47Å; H575-V596 VanDerWaalsContact CB-CG2 3.47Å; H575-V596 WeakPolarHBondContact ND1-CG2 3.32Å; G577-V596 VanDerWaalsContact C-CG1 3.44Å; G577-V596 VanDerWaalsContact CA-CG1 3.48Å; G577-V596 WeakPolarHBondContact O-CG1 3.44Å; E578-V596 CarbonylContact O-C 3.54Å; E578-V596 VanDerWaalsContact O-CA 3.32Å; E578-V596 WeakPolarHBondContact O-CA 3.31Å; I579-V596 HydrophobicContact CD1-CG2 3.98Å
597I71.6Confident80.8Confident36 Ų3644.2 Ų44.219%0.18525%0.252CS..EExtended strand (participates in β ladder)trans-107.2131.4159.9-168165.9000109.1F254 L286 G577 E578F254-I597 HydrophobicContact CD1-CD1 3.84Å; F254-I597 HydrophobicContact CE1-CB 4.47Å; F254-I597 HydrophobicContact CE1-CD1 3.09Å; F254-I597 HydrophobicContact CE1-CG1 4.34Å; F254-I597 HydrophobicContact CE1-CG2 4.4Å; F254-I597 HydrophobicContact CE2-CD1 4.19Å; F254-I597 HydrophobicContact CZ-CD1 3.28Å; L286-I597 HydrophobicContact CD1-CD1 3.89Å; L286-I597 HydrophobicContact CD1-CG1 4.49Å; G577-I597 CarbonylContact C-O 3.55Å; E578-I597 HydrophobicContact CB-CG2 4.08Å; E578-I597 PolarHBondContact N-O 2.82Å; E578-I597 VanDerWaalsContact N-O 3.12Å; E578-I597 PolarHBondContact O-N 3.49Å
598G55.5Low80.2Confident46 Ų4645.1 Ų45.147%0.47426%0.263SS..  trans161.8161-174.700000113.3
599V49Very low79.9Confident51 Ų5145 Ų4531%0.30926%0.263SS..SBendtrans-41.2146-174.8-174.10000112.4P601 V659 Y733V599-P601 WeakPolarHBondContact O-CD 3.37Å; V599-V659 HydrophobicContact CG2-CG1 4.38Å; V599-Y733 HydrophobicContact CG1-CD2 4.32Å; V599-Y733 HydrophobicContact CG1-CE2 3.84Å
600R53.3Low79.6Confident116 Ų11644 Ų4444%0.43825%0.254SS..  trans-43.1114.7171.1-81.7-171.7-174.9-178.36.3108.7C602 Y733 T734R600-C602 PolarHBondContact O-N 3.26Å; R600-Y733 HydrophobicContact CB-CD2 4.44Å; R600-T734 VanDerWaalsContact NH1-C 3.33Å; R600-T734 PolarHBondContact NH1-O 3.22Å
601P64Low79.2Confident47 Ų4741.9 Ų41.931%0.30525%0.249SC..  trans-61.4135.3-174.722.2-31.7000108.4V599 V604V599-P601 WeakPolarHBondContact O-CD 3.37Å; P601-V604 HydrophobicContact CG-CG2 4.03Å
602C83.3Confident78.6Confident19 Ų1944.2 Ų44.213%0.12826%0.264CS..THydrogen-bonded Turntrans-50.9156.1171.760.80000110.9R600 V604 D655 P739 C741 R822R600-C602 PolarHBondContact O-N 3.26Å; C602-V604 PolarHBondContact O-N 3.45Å; C602-D655 HydrophobicContact CB-CB 4.42Å; C602-P739 HydrophobicContact CB-CB 4.47Å; C602-P739 HydrophobicContact CB-CG 4.03Å; C602-C741 HydrophobicContact CB-CB 4.05Å; C602-C741 WeakPolarHBondContact CB-SG 3.42Å; C602-C741 PolarHBondContact O-SG 2.71Å; C602-C741 WeakPolarHBondContact SG-CA 3.43Å; C602-C741 WeakPolarHBondContact SG-CB 3.48Å; C602-C741 CovalentContact SG-SG 2.05Å; C602-C741 PolarHBondContact SG-SG 3.33Å; C602-R822 PolarHBondContact O-NE 3.05Å; C602-R822 PolarHBondContact O-NH2 3.27Å; C602-R822 PolarHBondContact SG-NH2 2.76Å
603G88Confident77.6Confident0 Ų044.1 Ų44.10%027%0.267CS..THydrogen-bonded Turntrans73.87.9173.500000115.1P605 P739 Y823G603-P605 WeakPolarHBondContact O-CD 3.25Å; G603-P739 PolarHBondContact N-O 2.94Å; G603-Y823 WeakPolarHBondContact CA-O 3.49Å; G603-Y823 WeakPolarHBondContact O-CD2 3.25Å; G603-Y823 PolarHBondContact O-N 2.97Å
604V81.3Confident76.3Confident47 Ų4749 Ų4929%0.28530%0.296SS..  trans-112.498.7175.8-174.50000109.9P601 C602 R822P601-V604 HydrophobicContact CG-CG2 4.03Å; C602-V604 PolarHBondContact O-N 3.45Å; V604-R822 HydrophobicContact CG2-CG 3.78Å
605P84.4Confident74.6Confident17 Ų1752.3 Ų52.311%0.1131%0.31CS..  trans-74.8141.2178.730.9-34000111.2G603 I607 P609 S631 P633 W634 Y823G603-P605 WeakPolarHBondContact O-CD 3.25Å; P605-I607 PolarHBondContact O-N 3.03Å; P605-P609 HydrophobicContact CG-CG 4.04Å; P605-S631 WeakPolarHBondContact CB-O 3.4Å; P605-P633 HydrophobicContact CB-CG 3.86Å; P605-W634 HydrophobicContact CB-CH2 4.41Å; P605-W634 HydrophobicContact CB-CZ3 4.08Å; P605-W634 HydrophobicContact CG-CH2 4.19Å; P605-W634 HydrophobicContact CG-CZ3 4.2Å; P605-Y823 HydrophobicContact CG-CD2 4.33Å; P605-Y823 HydrophobicContact CG-CE2 4.2Å
606A73.1Confident72.6Confident59 Ų5960.1 Ų60.149%0.48834%0.344SS..SBendtrans-64.5-26175.800000112.7K735A606-K735 HydrophobicContact CB-CB 3.89Å; A606-K735 HydrophobicContact CB-CG 4.02Å
607I78.8Confident70.7Confident49 Ų4965.4 Ų65.425%0.25137%0.371SS..SBendtrans-116.2117.3176.5-59.7170.1000107.4P605 R628 N630 S631P605-I607 PolarHBondContact O-N 3.03Å; I607-R628 HydrophobicContact CG2-CG 3.92Å; I607-N630 HydrophobicContact CD1-CB 4.08Å; I607-S631 WeakPolarHBondContact O-CA 3.22Å; I607-S631 WeakPolarHBondContact O-CB 3.27Å
608S79.5Confident69.1Low81 Ų8170.7 Ų70.757%0.56639%0.393SS*.  trans-63132.3-177.7-50.40000112.3R628S608-R628 PolarHBondContact O-NH1 2.94Å
609P85.1Confident68.1Low15 Ų1574.1 Ų74.110%0.09741%0.409CS..  trans-64.9152.7174.8-20.931.2000112.8P605 K611 S631 L632 Y823P605-P609 HydrophobicContact CG-CG 4.04Å; P609-K611 PolarHBondContact O-N 2.91Å; P609-S631 WeakPolarHBondContact CG-O 3.42Å; P609-L632 HydrophobicContact CB-CD2 4.07Å; P609-L632 HydrophobicContact CG-CD2 3.89Å; P609-Y823 HydrophobicContact CG-CE2 3.97Å
610L83.7Confident67.3Low32 Ų3283.3 Ų83.317%0.16844%0.438CS..  trans-75.9107.3170.8-70.8172.1000109.8V612 T614 W625 R628 Q774L610-V612 VanDerWaalsContact C-N 3.28Å; L610-V612 PolarHBondContact O-N 3.48Å; L610-T614 HydrophobicContact CD1-CG2 3.77Å; L610-T614 HydrophobicContact CD2-CG2 3.95Å; L610-W625 VanDerWaalsContact O-CZ2 3.29Å; L610-W625 WeakPolarHBondContact O-CZ2 3.06Å; L610-W625 PolarHBondContact O-NE1 2.92Å; L610-R628 HydrophobicContact CD1-CB 4.36Å; L610-R628 HydrophobicContact CG-CB 4.26Å; L610-Q774 PolarHBondContact O-NE2 3.44Å
611K82.2Confident66.1Low88 Ų8884 Ų8438%0.38345%0.45SS..SBendtrans-71.1-26.7178.9-58.5-175.6-173.1-173.80112.5P609 F756 R776 E818P609-K611 PolarHBondContact O-N 2.91Å; K611-F756 HydrophobicContact CB-CZ 4.26Å; K611-F756 HydrophobicContact CG-CZ 4.38Å; K611-R776 PolarHBondContact O-NE 3.21Å; K611-R776 PolarHBondContact O-NH1 2.99Å; K611-R776 PolarHBondContact O-NH2 3.27Å; K611-E818 WeakPolarHBondContact CE-OE1 3.37Å; K611-E818 WeakPolarHBondContact CE-OE2 3.5Å; K611-E818 IonicContact NZ-OE1 3.4Å; K611-E818 PolarHBondContact NZ-OE1 3.07Å; K611-E818 IonicContact NZ-OE2 3.45Å; K611-E818 PolarHBondContact NZ-OE2 2.83Å
612V80Confident64.7Low75 Ų7583.9 Ų83.946%0.45545%0.45SS..SBendtrans-127.3154.6179-73.30000110.3L610 R776L610-V612 VanDerWaalsContact C-N 3.28Å; L610-V612 PolarHBondContact O-N 3.48Å; V612-R776 VanDerWaalsContact CG1-NH1 3.31Å
613P75Confident63.5Low45 Ų4585.5 Ų85.529%0.29246%0.455SS..  trans-57.2143.2170.9-2029.4000112.2W625P613-W625 HydrophobicContact CB-CB 4.37Å; P613-W625 HydrophobicContact CB-CD2 4.4Å; P613-W625 HydrophobicContact CB-CE3 4.46Å; P613-W625 HydrophobicContact CB-CG 4.39Å; P613-W625 HydrophobicContact CG-CD2 4.01Å; P613-W625 HydrophobicContact CG-CE3 3.66Å; P613-W625 HydrophobicContact CG-CG 4.49Å; P613-W625 HydrophobicContact CG-CZ3 4.06Å
614T67.2Low62.7Low115 Ų11587 Ų8771%0.70647%0.47SS*.SBendtrans-74.4-31.4179.145.60000113.3L610L610-T614 HydrophobicContact CD1-CG2 3.77Å; L610-T614 HydrophobicContact CD2-CG2 3.95Å
615N59.7Low62.9Low108 Ų10885.7 Ų85.758%0.57846%0.46SS*.  trans-99.4103.3-175.5-149-9.8000110.9
616K49.8Very low63.1Low182 Ų18289.8 Ų89.879%0.79148%0.478SS*.  trans-83.9-15.9178.7-71.6-174.4178.8-179.70114.1
617N40.9Very low63.9Low145 Ų14587 Ų8778%0.77546%0.455SS*.  trans-95.46-164.7-83.40.1000116.5
618F38.3Very low64.5Low147 Ų14790.2 Ų90.265%0.64546%0.464SS*.  trans-103.283163.5-74.5-81.5000109.5R620F618-R620 PolarHBondContact O-N 2.82Å
619S34.1Very low65Low118 Ų11889.3 Ų89.383%0.82546%0.456SS*.THydrogen-bonded Turntrans-50.4104.5156.5-49.20000107.8
620R31.2Very low65.2Low244 Ų24490 Ų9092%0.92146%0.459SS*.THydrogen-bonded Turntrans104.718.1163.4-147.4-176.3-165.3166.75.1120.8F618F618-R620 PolarHBondContact O-N 2.82Å
621I28.7Very low65.6Low131 Ų13188.5 Ų88.567%0.67245%0.451SS*.  trans-124.4119.1175.2-51.3-173.2000114.9
622S34.8Very low66.2Low45 Ų4584.6 Ų84.632%0.31544%0.435SS..  trans3150.7157.1-32.50000123.5
623F57.5Low67Low53 Ų5381.3 Ų81.323%0.23242%0.415CS..SBendcis-153.943.3-36.1-82.6-42.7000109.3R802 R803 S804F623-R802 WeakPolarHBondContact CD1-O 3.13Å; F623-R802 WeakPolarHBondContact CE1-O 3.46Å; F623-R803 VanDerWaalsContact CB-O 3.28Å; F623-R803 WeakPolarHBondContact CB-O 3.26Å; F623-R803 VanDerWaalsContact CD1-C 3.5Å; F623-R803 HydrophobicContact CD1-CB 3.47Å; F623-R803 VanDerWaalsContact CD1-CB 3.47Å; F623-R803 HydrophobicContact CD2-CB 3.61Å; F623-R803 HydrophobicContact CE1-CB 3.49Å; F623-R803 VanDerWaalsContact CE1-CB 3.49Å; F623-R803 HydrophobicContact CE1-CG 4.29Å; F623-R803 HydrophobicContact CE2-CB 3.6Å; F623-R803 HydrophobicContact CE2-CG 4.16Å; F623-R803 HydrophobicContact CG-CB 3.6Å; F623-R803 VanDerWaalsContact CG-O 3.26Å; F623-R803 WeakPolarHBondContact CG-O 3.48Å; F623-R803 HydrophobicContact CZ-CB 3.56Å; F623-R803 HydrophobicContact CZ-CG 4.03Å; F623-S804 VanDerWaalsContact O-CA 3.27Å; F623-S804 WeakPolarHBondContact O-CA 3.33Å; F623-S804 VanDerWaalsContact O-CB 3.28Å; F623-S804 WeakPolarHBondContact O-CB 3.36Å; F623-S804 PolarHBondContact O-OG 3.13Å
624G70.7Confident68.1Low31 Ų3179.2 Ų79.232%0.3240%0.401SS..  trans163.1172.4178.300000108.2S804G624-S804 PolarHBondContact N-OG 2.97Å
625W85.6Confident69.5Low20 Ų2074 Ų748%0.07637%0.368CS..EExtended strand (participates in β ladder)trans-130.1151.617165.796.7000111.7L610 P613 A627 K773 Q774 R776 Y801L610-W625 VanDerWaalsContact O-CZ2 3.29Å; L610-W625 WeakPolarHBondContact O-CZ2 3.06Å; L610-W625 PolarHBondContact O-NE1 2.92Å; P613-W625 HydrophobicContact CB-CB 4.37Å; P613-W625 HydrophobicContact CB-CD2 4.4Å; P613-W625 HydrophobicContact CB-CE3 4.46Å; P613-W625 HydrophobicContact CB-CG 4.39Å; P613-W625 HydrophobicContact CG-CD2 4.01Å; P613-W625 HydrophobicContact CG-CE3 3.66Å; P613-W625 HydrophobicContact CG-CG 4.49Å; P613-W625 HydrophobicContact CG-CZ3 4.06Å; W625-A627 PolarHBondContact O-N 2.63Å; W625-K773 CarbonylContact O-C 3.54Å; W625-K773 WeakPolarHBondContact O-CA 3.25Å; W625-Q774 HydrophobicContact CD2-CG 4.32Å; W625-Q774 VanDerWaalsContact CE2-NE2 3.32Å; W625-Q774 HydrophobicContact CG-CG 4.48Å; W625-Q774 HydrophobicContact CZ2-CG 4.19Å; W625-Q774 VanDerWaalsContact CZ2-NE2 3.33Å; W625-Q774 PolarHBondContact N-O 3.03Å; W625-Q774 PolarHBondContact O-N 3.28Å; W625-R776 HydrophobicContact CH2-CG 4.19Å; W625-Y801 HydrophobicContact CH2-CE2 4.18Å; W625-Y801 HydrophobicContact CZ3-CD2 4.11Å; W625-Y801 AromaticContact CZ3-CE2 3.72Å; W625-Y801 HydrophobicContact CZ3-CE2 3.72Å
626E89.5Confident71.3Confident102 Ų10268.8 Ų68.848%0.47734%0.341SS..EExtended strand (participates in β ladder)trans-60.9128.9174.1-168.4179.4154.200109.6H691 A771E626-H691 IonicContact OE1-CD2 3.85Å; E626-H691 IonicContact OE1-CE1 2.76Å; E626-H691 IonicContact OE1-NE2 3.56Å; E626-H691 PolarHBondContact OE1-NE2 2.77Å; E626-A771 HydrophobicContact CG-CB 4.01Å
627A90.5Very high73.5Confident2 Ų261 Ų612%0.01731%0.307CS..PPolyproline II helixtrans-62.8151.9173.100000109.2W625 L632 H691 L772 Q774W625-A627 PolarHBondContact O-N 2.63Å; A627-L632 HydrophobicContact CB-CD1 4.18Å; A627-L632 HydrophobicContact CB-CG 4.49Å; A627-H691 PolarHBondContact O-CE1 3.19Å; A627-L772 HydrophobicContact CB-CD2 4.25Å; A627-L772 HydrophobicContact CB-CG 4.18Å; A627-L772 PolarHBondContact N-O 2.92Å; A627-Q774 HydrophobicContact CB-CG 4.16Å
628R89.7Confident76.2Confident115 Ų11554.2 Ų54.243%0.43427%0.271SS..PPolyproline II helixtrans-62.7135.9167.6177.7-177.4-73.1172.4-5.7107.4I607 S608 L610 N630 S631I607-R628 HydrophobicContact CG2-CG 3.92Å; S608-R628 PolarHBondContact O-NH1 2.94Å; L610-R628 HydrophobicContact CD1-CB 4.36Å; L610-R628 HydrophobicContact CG-CB 4.26Å; R628-N630 PolarHBondContact O-N 3.29Å; R628-S631 PolarHBondContact N-OG 2.71Å; R628-S631 VanDerWaalsContact O-CB 3.22Å; R628-S631 WeakPolarHBondContact O-CB 3.35Å; R628-S631 PolarHBondContact O-N 2.63Å; R628-S631 PolarHBondContact O-OG 3.16Å
629P90.7Very high78.9Confident63 Ų6347.6 Ų47.641%0.40924%0.242SC..THydrogen-bonded Turntrans-47.3129.6-179.6-30.734.8000112.2S631 H691P629-S631 PolarHBondContact O-N 3.05Å; P629-H691 HydrophobicContact CB-CB 4.38Å
630N90.4Very high81.7Confident30 Ų3042.1 Ų42.116%0.1620%0.204CC..THydrogen-bonded Turntrans57.316178.6-48.4105.2000115.6I607 R628 L632 G689 E736I607-N630 HydrophobicContact CD1-CB 4.08Å; R628-N630 PolarHBondContact O-N 3.29Å; N630-L632 VanDerWaalsContact C-N 3.3Å; N630-L632 PolarHBondContact O-N 3.15Å; N630-G689 PolarHBondContact ND2-O 3.46Å; N630-E736 HydrophobicContact CB-CB 4.02Å; N630-E736 HydrophobicContact CB-CG 3.84Å
631S91Very high84.4Confident0 Ų035.8 Ų35.80%018%0.181CC..SBendtrans-76.7-15176.764.60000114.5P605 I607 P609 R628 P629 P633P605-S631 WeakPolarHBondContact CB-O 3.4Å; I607-S631 WeakPolarHBondContact O-CA 3.22Å; I607-S631 WeakPolarHBondContact O-CB 3.27Å; P609-S631 WeakPolarHBondContact CG-O 3.42Å; R628-S631 PolarHBondContact N-OG 2.71Å; R628-S631 VanDerWaalsContact O-CB 3.22Å; R628-S631 WeakPolarHBondContact O-CB 3.35Å; R628-S631 PolarHBondContact O-N 2.63Å; R628-S631 PolarHBondContact O-OG 3.16Å; P629-S631 PolarHBondContact O-N 3.05Å; S631-P633 VanDerWaalsContact O-CD 3.24Å; S631-P633 WeakPolarHBondContact O-CD 2.88Å
632L96.1Very high86.9Confident6 Ų631.6 Ų31.63%0.03116%0.159CC..SBendtrans-115.870.5174-58.4-179.5000109.9P609 A627 N630 W634 M635 A758 L772 Q774 F816P609-L632 HydrophobicContact CB-CD2 4.07Å; P609-L632 HydrophobicContact CG-CD2 3.89Å; A627-L632 HydrophobicContact CB-CD1 4.18Å; A627-L632 HydrophobicContact CB-CG 4.49Å; N630-L632 VanDerWaalsContact C-N 3.3Å; N630-L632 PolarHBondContact O-N 3.15Å; L632-W634 HydrophobicContact CD2-CH2 4.38Å; L632-W634 HydrophobicContact CD2-CZ2 3.72Å; L632-W634 PolarHBondContact O-N 3.32Å; L632-W634 VanDerWaalsContact O-N 3.15Å; L632-M635 HydrophobicContact CB-CG 3.69Å; L632-M635 HydrophobicContact CD1-CG 4.37Å; L632-M635 WeakPolarHBondContact O-CB 3.01Å; L632-M635 WeakPolarHBondContact O-CG 3.49Å; L632-M635 PolarHBondContact O-N 3.26Å; L632-M635 VanDerWaalsContact O-N 3.16Å; L632-A758 HydrophobicContact CD1-CB 3.45Å; L632-A758 VanDerWaalsContact CD1-CB 3.45Å; L632-L772 HydrophobicContact CB-CD2 4.07Å; L632-L772 HydrophobicContact CD1-CD2 4.07Å; L632-Q774 HydrophobicContact CD1-CB 4.24Å; L632-F816 HydrophobicContact CD1-CZ 3.97Å; L632-F816 HydrophobicContact CD2-CE2 3.74Å; L632-F816 HydrophobicContact CD2-CZ 3.7Å; L632-F816 HydrophobicContact CG-CZ 4.49Å
633P95.4Very high89.1Confident5 Ų535.9 Ų35.93%0.03218%0.178CC..THydrogen-bonded Turntrans-73.2-6.6-166.833.2-40.6000114.6P605 S631 E736 I737 S738P605-P633 HydrophobicContact CB-CG 3.86Å; S631-P633 VanDerWaalsContact O-CD 3.24Å; S631-P633 WeakPolarHBondContact O-CD 2.88Å; P633-E736 WeakPolarHBondContact CA-O 3.48Å; P633-E736 VanDerWaalsContact CB-O 3.28Å; P633-E736 WeakPolarHBondContact CB-O 3.26Å; P633-I737 WeakPolarHBondContact O-CA 3.36Å; P633-S738 CarbonylContact C-O 3.55Å; P633-S738 VanDerWaalsContact C-O 3.31Å; P633-S738 WeakPolarHBondContact CB-OG 3.47Å; P633-S738 WeakPolarHBondContact CG-OG 3.48Å; P633-S738 PolarHBondContact O-N 3.34Å
634W97.7Very high90.1Very high1 Ų145.4 Ų45.40%0.00421%0.212CC..THydrogen-bonded Turntrans-87.6-10.5174.248.180.8000113.1P605 L632 F652 L653 S738 V740 F816 Y823P605-W634 HydrophobicContact CB-CH2 4.41Å; P605-W634 HydrophobicContact CB-CZ3 4.08Å; P605-W634 HydrophobicContact CG-CH2 4.19Å; P605-W634 HydrophobicContact CG-CZ3 4.2Å; L632-W634 HydrophobicContact CD2-CH2 4.38Å; L632-W634 HydrophobicContact CD2-CZ2 3.72Å; L632-W634 PolarHBondContact O-N 3.32Å; L632-W634 VanDerWaalsContact O-N 3.15Å; W634-F652 CarbonylContact O-C 3.47Å; W634-F652 WeakPolarHBondContact O-CA 3.24Å; W634-L653 PolarHBondContact O-N 3.35Å; W634-S738 WeakPolarHBondContact CA-O 3.27Å; W634-S738 WeakPolarHBondContact CB-O 3.42Å; W634-S738 PolarHBondContact N-O 2.91Å; W634-V740 HydrophobicContact CB-CB 3.89Å; W634-V740 HydrophobicContact CB-CG1 4.22Å; W634-V740 HydrophobicContact CD2-CB 3.74Å; W634-V740 HydrophobicContact CD2-CG2 4.2Å; W634-V740 HydrophobicContact CE3-CB 4.1Å; W634-V740 HydrophobicContact CG-CB 3.64Å; W634-V740 HydrophobicContact CG-CG1 4.22Å; W634-V740 HydrophobicContact CG-CG2 4.45Å; W634-F816 AromaticContact CZ2-CD2 3.79Å; W634-F816 HydrophobicContact CZ2-CD2 3.79Å; W634-F816 AromaticContact CZ2-CE2 3.87Å; W634-F816 HydrophobicContact CZ2-CE2 3.87Å; W634-F816 HydrophobicContact CZ2-CG 4.41Å; W634-Y823 HydrophobicContact CH2-CD1 4.49Å; W634-Y823 AromaticContact CH2-CD2 3.63Å; W634-Y823 HydrophobicContact CH2-CD2 3.63Å; W634-Y823 HydrophobicContact CH2-CE2 4.42Å; W634-Y823 AromaticContact CH2-CG 3.66Å; W634-Y823 HydrophobicContact CH2-CG 3.66Å; W634-Y823 HydrophobicContact CZ2-CD2 4.45Å; W634-Y823 HydrophobicContact CZ2-CG 4.1Å; W634-Y823 HydrophobicContact CZ3-CD2 4.41Å
635M97.5Very high90.7Very high5 Ų547.1 Ų47.13%0.02522%0.217CC..EExtended strand (participates in β ladder)trans-67.8136.2-176.1-67.9-59.2-58.900111.6L632 A758 W760 L772 P814L632-M635 HydrophobicContact CB-CG 3.69Å; L632-M635 HydrophobicContact CD1-CG 4.37Å; L632-M635 WeakPolarHBondContact O-CB 3.01Å; L632-M635 WeakPolarHBondContact O-CG 3.49Å; L632-M635 PolarHBondContact O-N 3.26Å; L632-M635 VanDerWaalsContact O-N 3.16Å; M635-A758 HydrophobicContact CE-CB 4.19Å; M635-A758 WeakPolarHBondContact CE-O 3.48Å; M635-A758 HydrophobicContact SD-CB 4.19Å; M635-W760 HydrophobicContact CB-CH2 3.68Å; M635-W760 HydrophobicContact CB-CZ3 4.08Å; M635-W760 HydrophobicContact CE-CZ3 4.23Å; M635-L772 HydrophobicContact CB-CD2 4.24Å; M635-L772 HydrophobicContact CE-CD1 4.31Å; M635-L772 HydrophobicContact CG-CD1 4.46Å; M635-L772 HydrophobicContact CG-CD2 3.99Å; M635-P814 HydrophobicContact SD-CG 3.92Å
636V97.8Very high90.8Very high0 Ų053.2 Ų53.20%024%0.24CC..EExtended strand (participates in β ladder)trans-126131.8-178.6176.70000109.5I638 S650 G651 L653 V665 I686 F687 L688V636-I638 HydrophobicContact CG1-CG1 4.01Å; V636-S650 CarbonylContact O-C 3.31Å; V636-S650 WeakPolarHBondContact O-CA 3.36Å; V636-G651 PolarHBondContact N-O 3.27Å; V636-G651 PolarHBondContact O-N 3.07Å; V636-L653 HydrophobicContact CG2-CB 4.45Å; V636-V665 HydrophobicContact CB-CG1 4.31Å; V636-V665 HydrophobicContact CG1-CG1 4.08Å; V636-V665 HydrophobicContact CG2-CG1 4.25Å; V636-V665 HydrophobicContact CG2-CG2 4.14Å; V636-I686 HydrophobicContact CG1-CG2 3.28Å; V636-F687 WeakPolarHBondContact CA-O 3.08Å; V636-L688 HydrophobicContact CG2-CD2 3.92Å; V636-L688 HydrophobicContact CG2-CG 4.13Å
637H96.6Very high90.8Very high17 Ų1751.1 Ų51.18%0.07923%0.229CC..EExtended strand (participates in β ladder)trans-98.2126.6169.4-178.369.8000109.6F687 L693 W760H637-F687 HydrophobicContact CB-CB 4.21Å; H637-F687 PolarHBondContact N-O 2.98Å; H637-F687 PolarHBondContact O-N 2.84Å; H637-L693 HydrophobicContact CB-CD2 4.16Å; H637-W760 HydrophobicContact CB-CE3 4.14Å; H637-W760 HydrophobicContact CB-CH2 4.5Å; H637-W760 HydrophobicContact CB-CZ3 4.03Å
638I96.9Very high90.9Very high3 Ų354 Ų542%0.01525%0.246CC..EExtended strand (participates in β ladder)trans-110.9122.2-176.5-57.1-179.6000108.7V636 T648 C649 T667 F684 I686 L725V636-I638 HydrophobicContact CG1-CG1 4.01Å; I638-T648 WeakPolarHBondContact O-CA 3.45Å; I638-C649 HydrophobicContact CB-CB 4.2Å; I638-C649 PolarHBondContact N-O 3.3Å; I638-C649 PolarHBondContact O-N 3.14Å; I638-T667 HydrophobicContact CD1-CG2 3.7Å; I638-F684 HydrophobicContact CG2-CD1 4.07Å; I638-I686 HydrophobicContact CB-CD1 4.4Å; I638-I686 HydrophobicContact CD1-CD1 4.43Å; I638-I686 HydrophobicContact CG1-CD1 3.97Å; I638-I686 HydrophobicContact CG2-CD1 3.98Å; I638-L725 HydrophobicContact CD1-CD1 4.07Å
639L94.4Very high91.1Very high9 Ų949.2 Ų49.25%0.04723%0.23CC..EExtended strand (participates in β ladder)trans-114.2124.4177.3-179.462.2000109.1Y641 R646 T648 F684 L685 F687L639-Y641 HydrophobicContact CD1-CE2 4.31Å; L639-Y641 HydrophobicContact CD2-CE2 3.68Å; L639-Y641 WeakPolarHBondContact CD2-OH 3.49Å; L639-Y641 HydrophobicContact CG-CD2 4.41Å; L639-Y641 HydrophobicContact CG-CE2 3.65Å; L639-R646 HydrophobicContact CD1-CG 3.58Å; L639-T648 HydrophobicContact CD1-CG2 4.21Å; L639-F684 CarbonylContact O-C 3.22Å; L639-F684 WeakPolarHBondContact O-CA 3.48Å; L639-L685 HydrophobicContact CB-CB 4.37Å; L639-L685 PolarHBondContact N-O 3.32Å; L639-L685 PolarHBondContact O-N 3.05Å; L639-F687 HydrophobicContact CB-CD2 4.48Å; L639-F687 HydrophobicContact CB-CE2 3.99Å; L639-F687 HydrophobicContact CD2-CE2 3.94Å; L639-F687 HydrophobicContact CD2-CZ 4.41Å
640A92.4Very high91.4Very high3 Ų346.2 Ų46.23%0.02521%0.211CC..EExtended strand (participates in β ladder)trans-122.6145.5177.500000112.3F647 M679 S683 F684A640-F647 HydrophobicContact CB-CB 4.28Å; A640-F647 PolarHBondContact N-O 2.83Å; A640-F647 PolarHBondContact O-N 3.08Å; A640-M679 HydrophobicContact CB-CE 4.35Å; A640-S683 CarbonylContact C-O 3.59Å; A640-S683 WeakPolarHBondContact CA-O 3.25Å; A640-F684 HydrophobicContact CB-CD1 3.66Å; A640-F684 HydrophobicContact CB-CE1 3.7Å
641Y88.1Confident91.7Very high110 Ų11044.8 Ų44.843%0.43120%0.203SC..EExtended strand (participates in β ladder)trans-125.9119.2177.1-65.8-85.1000110.9L639 T645 R646 S683 L685L639-Y641 HydrophobicContact CD1-CE2 4.31Å; L639-Y641 HydrophobicContact CD2-CE2 3.68Å; L639-Y641 WeakPolarHBondContact CD2-OH 3.49Å; L639-Y641 HydrophobicContact CG-CD2 4.41Å; L639-Y641 HydrophobicContact CG-CE2 3.65Å; Y641-T645 WeakPolarHBondContact CA-O 3.39Å; Y641-R646 HydrophobicContact CD1-CB 4.38Å; Y641-R646 HydrophobicContact CE1-CB 4.19Å; Y641-R646 HydrophobicContact CE1-CG 4.14Å; Y641-S683 PolarHBondContact N-O 2.62Å; Y641-S683 VanDerWaalsContact O-CB 3.31Å; Y641-S683 WeakPolarHBondContact O-CB 3.09Å; Y641-S683 PolarHBondContact O-OG 2.86Å; Y641-L685 HydrophobicContact CE2-CD1 4.31Å
642E82.1Confident92.1Very high44 Ų4444.8 Ų44.821%0.20620%0.203CC..EExtended strand (participates in β ladder)trans-137.1126.6177.7-168.766.7-154.200108.9R644 T645 F647 Y674 M679 S683E642-R644 PolarHBondContact O-N 3.33Å; E642-R644 VanDerWaalsContact O-N 3.14Å; E642-T645 PolarHBondContact N-O 3.2Å; E642-T645 WeakPolarHBondContact O-CA 3.42Å; E642-T645 WeakPolarHBondContact O-CB 3.31Å; E642-T645 PolarHBondContact O-N 3.32Å; E642-F647 HydrophobicContact CB-CE2 3.99Å; E642-Y674 HydrophobicContact CG-CD1 4.24Å; E642-M679 HydrophobicContact CB-CG 4.36Å; E642-M679 HydrophobicContact CB-SD 3.69Å; E642-M679 HydrophobicContact CG-CG 4.09Å; E642-M679 HydrophobicContact CG-SD 4.05Å; E642-S683 PolarHBondContact OE2-OG 2.82Å
643N81.6Confident92.2Very high134 Ų13444.5 Ų44.572%0.71720%0.202SC*.THydrogen-bonded Turntrans47.443-178.3-65-43.4000114.4T645N643-T645 PolarHBondContact O-N 2.82Å; N643-T645 VanDerWaalsContact O-N 3.12Å
644R77.4Confident92.1Very high254 Ų25444.4 Ų44.496%0.95820%0.201SC*.THydrogen-bonded Turntrans62.76.6-174.8-53-177.4178.5-167.8-0.5115.5E642E642-R644 PolarHBondContact O-N 3.33Å; E642-R644 VanDerWaalsContact O-N 3.14Å
645T84.1Confident91.6Very high66 Ų6646.9 Ų46.941%0.40521%0.214SC..EExtended strand (participates in β ladder)trans-90.8132.8171.9-53.80000109.2Y641 E642 N643 F647Y641-T645 WeakPolarHBondContact CA-O 3.39Å; E642-T645 PolarHBondContact N-O 3.2Å; E642-T645 WeakPolarHBondContact O-CA 3.42Å; E642-T645 WeakPolarHBondContact O-CB 3.31Å; E642-T645 PolarHBondContact O-N 3.32Å; N643-T645 PolarHBondContact O-N 2.82Å; N643-T645 VanDerWaalsContact O-N 3.12Å; T645-F647 HydrophobicContact CG2-CD2 4.43Å; T645-F647 HydrophobicContact CG2-CE1 4.16Å; T645-F647 HydrophobicContact CG2-CE2 3.69Å; T645-F647 HydrophobicContact CG2-CZ 3.54Å
646R87.4Confident90.8Very high149 Ų14947.1 Ų47.156%0.56222%0.216SC*.EExtended strand (participates in β ladder)trans-95.1128.3178.6179.3-178.4170173.84.4109.7L639 Y641L639-R646 HydrophobicContact CD1-CG 3.58Å; Y641-R646 HydrophobicContact CD1-CB 4.38Å; Y641-R646 HydrophobicContact CE1-CB 4.19Å; Y641-R646 HydrophobicContact CE1-CG 4.14Å
647F89.3Confident89.4Confident58 Ų5850.2 Ų50.225%0.25425%0.249SC..EExtended strand (participates in β ladder)trans-116.5146173.8-57.2-91000110.1A640 E642 T645 Y674A640-F647 HydrophobicContact CB-CB 4.28Å; A640-F647 PolarHBondContact N-O 2.83Å; A640-F647 PolarHBondContact O-N 3.08Å; E642-F647 HydrophobicContact CB-CE2 3.99Å; T645-F647 HydrophobicContact CG2-CD2 4.43Å; T645-F647 HydrophobicContact CG2-CE1 4.16Å; T645-F647 HydrophobicContact CG2-CE2 3.69Å; T645-F647 HydrophobicContact CG2-CZ 3.54Å; F647-Y674 AromaticContact CE1-CD2 3.98Å; F647-Y674 HydrophobicContact CE1-CD2 3.98Å; F647-Y674 AromaticContact CE1-CE2 3.92Å; F647-Y674 HydrophobicContact CE1-CE2 3.92Å; F647-Y674 AromaticContact CZ-CD2 3.79Å; F647-Y674 HydrophobicContact CZ-CD2 3.79Å; F647-Y674 HydrophobicContact CZ-CE1 4.43Å; F647-Y674 AromaticContact CZ-CE2 3.64Å; F647-Y674 HydrophobicContact CZ-CE2 3.64Å; F647-Y674 HydrophobicContact CZ-CG 4.26Å; F647-Y674 AromaticContact CZ-CZ 3.99Å
648T91.7Very high87.7Confident62 Ų6251.3 Ų51.338%0.3826%0.255SS..EExtended strand (participates in β ladder)trans-129.7126.1179.554.30000109.9I638 L639I638-T648 WeakPolarHBondContact O-CA 3.45Å; L639-T648 HydrophobicContact CD1-CG2 4.21Å
649C95.2Very high86Confident14 Ų1456.7 Ų56.710%0.09529%0.288CS..EExtended strand (participates in β ladder)trans-130.8174.3172.1-81.80000110I638 C671 G809I638-C649 HydrophobicContact CB-CB 4.2Å; I638-C649 PolarHBondContact N-O 3.3Å; I638-C649 PolarHBondContact O-N 3.14Å; C649-C671 HydrophobicContact CB-CB 3.75Å; C649-C671 WeakPolarHBondContact CB-SG 3.35Å; C649-C671 WeakPolarHBondContact SG-CB 3.3Å; C649-C671 CovalentContact SG-SG 2.04Å; C649-C671 PolarHBondContact SG-SG 3.29Å; C649-G809 CarbonylContact C-O 3.53Å
650S95.8Very high84.7Confident0 Ų059.8 Ų59.80%030%0.304CS..EExtended strand (participates in β ladder)trans-116.3164.9171.3-62.50000110.1V636 T667 G809 S811 G812V636-S650 CarbonylContact O-C 3.31Å; V636-S650 WeakPolarHBondContact O-CA 3.36Å; S650-T667 PolarHBondContact O-OG1 2.66Å; S650-G809 PolarHBondContact N-O 3.07Å; S650-G809 PolarHBondContact OG-O 2.95Å; S650-S811 CarbonylContact C-O 3.53Å; S650-S811 PolarHBondContact N-O 3.12Å; S650-G812 CarbonylContact O-C 3.59Å; S650-G812 VanDerWaalsContact O-C 3.29Å; S650-G812 WeakPolarHBondContact O-CA 3.36Å
651G97.9Very high84.1Confident0 Ų062.3 Ų62.30%032%0.316CS..EExtended strand (participates in β ladder)trans-158.2-171.8174.900000110.4V636 V666V636-G651 PolarHBondContact N-O 3.27Å; V636-G651 PolarHBondContact O-N 3.07Å; G651-V666 CarbonylContact C-O 3.51Å; G651-V666 VanDerWaalsContact CA-O 3.23Å; G651-V666 WeakPolarHBondContact CA-O 3.17Å
652F98.5Very high84.1Confident0 Ų057.1 Ų57.10%030%0.295CS..EExtended strand (participates in β ladder)trans-147.3144.9175.855.2-81.5000113.4W634 I654 V665 V666 V740 P814 A825 V828W634-F652 CarbonylContact O-C 3.47Å; W634-F652 WeakPolarHBondContact O-CA 3.24Å; F652-I654 HydrophobicContact CD2-CG2 3.63Å; F652-I654 HydrophobicContact CE2-CG2 3.6Å; F652-V665 WeakPolarHBondContact O-CA 3.2Å; F652-V666 HydrophobicContact CD1-CB 4.38Å; F652-V666 HydrophobicContact CD2-CB 4.2Å; F652-V666 HydrophobicContact CE1-CB 3.89Å; F652-V666 HydrophobicContact CE1-CG1 3.87Å; F652-V666 HydrophobicContact CE2-CB 3.68Å; F652-V666 HydrophobicContact CE2-CG1 4.13Å; F652-V666 HydrophobicContact CE2-CG2 4.08Å; F652-V666 HydrophobicContact CZ-CB 3.52Å; F652-V666 HydrophobicContact CZ-CG1 3.5Å; F652-V666 VanDerWaalsContact CZ-CG1 3.5Å; F652-V666 HydrophobicContact CZ-CG2 4.3Å; F652-V666 PolarHBondContact N-O 3.4Å; F652-V666 PolarHBondContact O-N 3.18Å; F652-V740 HydrophobicContact CB-CG1 4.38Å; F652-V740 HydrophobicContact CD2-CG1 3.51Å; F652-V740 HydrophobicContact CE2-CG1 4.18Å; F652-V740 HydrophobicContact CG-CG1 4.3Å; F652-P814 HydrophobicContact CB-CB 4.24Å; F652-P814 HydrophobicContact CB-CG 3.79Å; F652-P814 HydrophobicContact CD1-CB 3.52Å; F652-P814 HydrophobicContact CD1-CG 3.81Å; F652-P814 HydrophobicContact CD2-CB 4.3Å; F652-P814 HydrophobicContact CE1-CB 3.82Å; F652-P814 HydrophobicContact CG-CB 3.76Å; F652-P814 HydrophobicContact CG-CG 3.88Å; F652-P814 HydrophobicContact CZ-CB 4.31Å; F652-A825 HydrophobicContact CD2-CB 4.08Å; F652-A825 HydrophobicContact CE2-CB 3.53Å; F652-A825 HydrophobicContact CZ-CB 3.97Å; F652-V828 HydrophobicContact CE1-CG1 4.48Å; F652-V828 HydrophobicContact CE1-CG2 3.93Å; F652-V828 HydrophobicContact CZ-CG2 3.9Å
653L98Very high84.7Confident0 Ų055.2 Ų55.20%029%0.286CS..EExtended strand (participates in β ladder)trans-78.1128.1175.2-170.674.7000109.8W634 V636 I664 V665 L688 Y733 I737 P739 V740W634-L653 PolarHBondContact O-N 3.35Å; V636-L653 HydrophobicContact CG2-CB 4.45Å; L653-I664 WeakPolarHBondContact CD1-O 3.17Å; L653-V665 HydrophobicContact CD1-CG2 4.23Å; L653-L688 HydrophobicContact CB-CD2 4.46Å; L653-L688 HydrophobicContact CD1-CD2 4.05Å; L653-L688 HydrophobicContact CD2-CD2 4.37Å; L653-Y733 HydrophobicContact CD2-CE1 4.4Å; L653-I737 HydrophobicContact CD2-CG2 3.83Å; L653-P739 HydrophobicContact CG-CB 4.4Å; L653-P739 VanDerWaalsContact O-CA 3.27Å; L653-P739 WeakPolarHBondContact O-CA 3.06Å; L653-V740 PolarHBondContact O-N 3.09Å
654I94.8Very high85.4Confident3 Ų348.8 Ų48.82%0.01525%0.252CS..EExtended strand (participates in β ladder)trans-111.5163172.162.5166.2000110.2F652 S662 I664 V666 P739 V740 L742 M860F652-I654 HydrophobicContact CD2-CG2 3.63Å; F652-I654 HydrophobicContact CE2-CG2 3.6Å; I654-S662 VanDerWaalsContact O-CB 3.29Å; I654-S662 WeakPolarHBondContact O-CB 3.45Å; I654-S662 PolarHBondContact O-OG 2.74Å; I654-I664 HydrophobicContact CD1-CB 4.45Å; I654-I664 HydrophobicContact CD1-CG2 3.72Å; I654-I664 HydrophobicContact CG1-CB 4Å; I654-I664 HydrophobicContact CG1-CG2 3.68Å; I654-I664 PolarHBondContact N-O 2.84Å; I654-V666 HydrophobicContact CD1-CG2 3.7Å; I654-V666 HydrophobicContact CG1-CG2 4.04Å; I654-V666 HydrophobicContact CG2-CG2 3.86Å; I654-P739 VanDerWaalsContact C-CB 3.4Å; I654-V740 HydrophobicContact CG2-CG1 4.39Å; I654-L742 HydrophobicContact CG2-CD1 4.25Å; I654-M860 HydrophobicContact CD1-SD 3.92Å
655D86.4Confident86.4Confident53 Ų5336.7 Ų36.728%0.28321%0.207SC..  trans-70.6131.5173.9-165.9-7.3000110C602 G657 Y733 P739C602-D655 HydrophobicContact CB-CB 4.42Å; D655-G657 PolarHBondContact OD1-N 3.42Å; D655-Y733 PolarHBondContact OD1-OH 3.5Å; D655-P739 HydrophobicContact CB-CB 4.36Å; D655-P739 HydrophobicContact CB-CG 4.17Å
656S80.4Confident87.1Confident10 Ų1033.6 Ų33.67%0.0719%0.187CC..  trans-105.16.4178.371.90000113.8L658 D663S656-L658 VanDerWaalsContact C-N 3.27Å; S656-D663 WeakPolarHBondContact CB-OD1 3.15Å; S656-D663 PolarHBondContact OG-N 3.26Å; S656-D663 PolarHBondContact OG-OD1 3.37Å
657G68.9Low87.5Confident66 Ų6626.5 Ų26.568%0.6816%0.16SC*.SBendtrans797.6-176.800000113.8D655D655-G657 PolarHBondContact OD1-N 3.42Å
658L60.6Low87.9Confident40 Ų4023.7 Ų23.721%0.20915%0.148CC..  trans-82.3142172.5-61.8174.9000110.2S656 N660 Q661 D663 P730S656-L658 VanDerWaalsContact C-N 3.27Å; L658-N660 PolarHBondContact O-N 2.89Å; L658-Q661 HydrophobicContact CB-CG 3.66Å; L658-Q661 WeakPolarHBondContact CB-O 3.46Å; L658-Q661 HydrophobicContact CD1-CG 4.19Å; L658-Q661 VanDerWaalsContact O-O 3.06Å; L658-D663 HydrophobicContact CD1-CB 4.45Å; L658-P730 HydrophobicContact CD1-CB 4.29Å; L658-P730 HydrophobicContact CD1-CG 4.15Å
659V61.7Low88Confident116 Ų11620.8 Ų20.870%0.70313%0.13SC*.THydrogen-bonded Turntrans-67.8117.3-179.1-178.70000110.6V599 Q661V599-V659 HydrophobicContact CG2-CG1 4.38Å; V659-Q661 PolarHBondContact O-N 3.26Å; V659-Q661 VanDerWaalsContact O-N 3.13Å
660N67.3Low87.9Confident74 Ų7422.2 Ų22.240%0.39614%0.135SC..THydrogen-bonded Turntrans57.823.2174.8-162.739.7000115.2L658 Y733L658-N660 PolarHBondContact O-N 2.89Å; N660-Y733 VanDerWaalsContact C-CD2 3.46Å; N660-Y733 PolarHBondContact O-N 2.97Å
661Q79.9Confident87.8Confident56 Ų5622.6 Ų22.626%0.26214%0.138SC..EExtended strand (participates in β ladder)trans-157161.317864.4-171.124.900110.6L658 V659 P730 V731 R732 Y733L658-Q661 HydrophobicContact CB-CG 3.66Å; L658-Q661 WeakPolarHBondContact CB-O 3.46Å; L658-Q661 HydrophobicContact CD1-CG 4.19Å; L658-Q661 VanDerWaalsContact O-O 3.06Å; V659-Q661 PolarHBondContact O-N 3.26Å; V659-Q661 VanDerWaalsContact O-N 3.13Å; Q661-P730 HydrophobicContact CB-CB 4.35Å; Q661-P730 HydrophobicContact CG-CB 4.15Å; Q661-V731 CarbonylContact C-O 3.55Å; Q661-V731 WeakPolarHBondContact CA-O 3.23Å; Q661-V731 VanDerWaalsContact CB-O 3.26Å; Q661-V731 WeakPolarHBondContact CB-O 3.35Å; Q661-R732 HydrophobicContact CB-CG 4.46Å; Q661-Y733 VanDerWaalsContact C-CZ 3.42Å; Q661-Y733 PolarHBondContact O-OH 2.8Å; Q661-Y733 VanDerWaalsContact O-OH 3.08Å
662S88.3Confident87.5Confident0 Ų022.7 Ų22.70%014%0.139CC..EExtended strand (participates in β ladder)trans-142.2155.7171.1171.90000110.9I654 I664 V731 Y733I654-S662 VanDerWaalsContact O-CB 3.29Å; I654-S662 WeakPolarHBondContact O-CB 3.45Å; I654-S662 PolarHBondContact O-OG 2.74Å; S662-I664 PolarHBondContact OG-N 3.47Å; S662-V731 PolarHBondContact N-O 3.23Å; S662-V731 PolarHBondContact O-N 3.49Å; S662-Y733 WeakPolarHBondContact CB-OH 2.88Å
663D93.1Very high87.1Confident4 Ų424 Ų242%0.02115%0.145CC..EExtended strand (participates in β ladder)trans-129.614.4178.760.3-11.7000113S656 L658 R726 L727 P730S656-D663 WeakPolarHBondContact CB-OD1 3.15Å; S656-D663 PolarHBondContact OG-N 3.26Å; S656-D663 PolarHBondContact OG-OD1 3.37Å; L658-D663 HydrophobicContact CD1-CB 4.45Å; D663-R726 CarbonylContact O-C 3.57Å; D663-R726 WeakPolarHBondContact O-CA 3.43Å; D663-R726 IonicContact OD1-NH1 2.69Å; D663-R726 IonicContact OD2-CZ 3.96Å; D663-R726 IonicContact OD2-NE 2.59Å; D663-R726 IonicContact OD2-NH1 2.72Å; D663-R726 PolarHBondContact OD2-NH1 2.84Å; D663-R726 IonicContact OD2-NH2 2.8Å; D663-R726 PolarHBondContact OD2-NH2 3.21Å; D663-L727 HydrophobicContact CB-CB 4.43Å; D663-L727 PolarHBondContact O-N 3.38Å; D663-P730 HydrophobicContact CB-CB 4.18Å; D663-P730 HydrophobicContact CB-CG 4.16Å
664I96.6Very high86.4Confident0 Ų029 Ų290%016%0.164CC..EExtended strand (participates in β ladder)trans-119.5125-176.9-57.2-67.1000111.5L653 I654 S662 L724 R726 M860 L863L653-I664 WeakPolarHBondContact CD1-O 3.17Å; I654-I664 HydrophobicContact CD1-CB 4.45Å; I654-I664 HydrophobicContact CD1-CG2 3.72Å; I654-I664 HydrophobicContact CG1-CB 4Å; I654-I664 HydrophobicContact CG1-CG2 3.68Å; I654-I664 PolarHBondContact N-O 2.84Å; S662-I664 PolarHBondContact OG-N 3.47Å; I664-L724 HydrophobicContact CG2-CD2 4.31Å; I664-L724 HydrophobicContact CG2-CG 4.14Å; I664-R726 HydrophobicContact CD1-CB 4.04Å; I664-R726 HydrophobicContact CD1-CG 3.99Å; I664-M860 HydrophobicContact CB-CG 4.49Å; I664-M860 HydrophobicContact CB-SD 4.2Å; I664-M860 HydrophobicContact CD1-CG 4.11Å; I664-M860 HydrophobicContact CG1-CG 3.9Å; I664-M860 HydrophobicContact CG1-SD 3.86Å; I664-M860 HydrophobicContact CG2-CG 4.02Å; I664-M860 HydrophobicContact CG2-SD 4.04Å; I664-L863 HydrophobicContact CD1-CD1 4.46Å
665V98.4Very high85.6Confident0 Ų031.7 Ų31.70%019%0.193CC..EExtended strand (participates in β ladder)trans-116134.6173.9173.30000109.5V636 F652 L653 I686 L725 L727V636-V665 HydrophobicContact CB-CG1 4.31Å; V636-V665 HydrophobicContact CG1-CG1 4.08Å; V636-V665 HydrophobicContact CG2-CG1 4.25Å; V636-V665 HydrophobicContact CG2-CG2 4.14Å; F652-V665 WeakPolarHBondContact O-CA 3.2Å; L653-V665 HydrophobicContact CD1-CG2 4.23Å; V665-I686 HydrophobicContact CG2-CG2 4.25Å; V665-L725 HydrophobicContact CB-CB 4.35Å; V665-L725 HydrophobicContact CG1-CD1 4.48Å; V665-L725 PolarHBondContact N-O 3.32Å; V665-L725 PolarHBondContact O-N 2.8Å; V665-L727 HydrophobicContact CG2-CD1 4.16Å; V665-L727 HydrophobicContact CG2-CD2 4.09Å; V665-L727 HydrophobicContact CG2-CG 4.29Å
666V98.3Very high85.1Confident0 Ų034.8 Ų34.80%021%0.209CC..EExtended strand (participates in β ladder)trans-101.8137.9172.6-177.20000109.3G651 F652 I654 I722 L724 V828G651-V666 CarbonylContact C-O 3.51Å; G651-V666 VanDerWaalsContact CA-O 3.23Å; G651-V666 WeakPolarHBondContact CA-O 3.17Å; F652-V666 HydrophobicContact CD1-CB 4.38Å; F652-V666 HydrophobicContact CD2-CB 4.2Å; F652-V666 HydrophobicContact CE1-CB 3.89Å; F652-V666 HydrophobicContact CE1-CG1 3.87Å; F652-V666 HydrophobicContact CE2-CB 3.68Å; F652-V666 HydrophobicContact CE2-CG1 4.13Å; F652-V666 HydrophobicContact CE2-CG2 4.08Å; F652-V666 HydrophobicContact CZ-CB 3.52Å; F652-V666 HydrophobicContact CZ-CG1 3.5Å; F652-V666 VanDerWaalsContact CZ-CG1 3.5Å; F652-V666 HydrophobicContact CZ-CG2 4.3Å; F652-V666 PolarHBondContact N-O 3.4Å; F652-V666 PolarHBondContact O-N 3.18Å; I654-V666 HydrophobicContact CD1-CG2 3.7Å; I654-V666 HydrophobicContact CG1-CG2 4.04Å; I654-V666 HydrophobicContact CG2-CG2 3.86Å; V666-I722 HydrophobicContact CG1-CD1 4.1Å; V666-I722 HydrophobicContact CG1-CG1 4.08Å; V666-L724 HydrophobicContact CG1-CD1 4.49Å; V666-L724 HydrophobicContact CG2-CD1 4.02Å; V666-L724 HydrophobicContact CG2-CG 4.31Å; V666-V828 HydrophobicContact CG1-CG2 3.84Å
667T97.5Very high85.2Confident0 Ų035.8 Ų35.80%022%0.215CC..EExtended strand (participates in β ladder)trans-152.4-174.8173.2-172.50000110.2I638 S650 V723 L725 G812I638-T667 HydrophobicContact CD1-CG2 3.7Å; S650-T667 PolarHBondContact O-OG1 2.66Å; T667-V723 HydrophobicContact CG2-CG1 3.32Å; T667-V723 PolarHBondContact N-O 3.4Å; T667-V723 VanDerWaalsContact N-O 3.15Å; T667-V723 PolarHBondContact O-N 3.01Å; T667-L725 HydrophobicContact CG2-CD1 3.94Å; T667-L725 HydrophobicContact CG2-CG 4.16Å; T667-G812 WeakPolarHBondContact OG1-CA 3.34Å
668A95.9Very high86Confident0 Ų037 Ų370%020%0.2CC..  trans-80.6142.8177.700000111.5H670 C671 D721 V723 V828A668-H670 VanDerWaalsContact C-N 3.3Å; A668-H670 WeakPolarHBondContact CB-ND1 3.31Å; A668-H670 PolarHBondContact O-N 3.32Å; A668-C671 VanDerWaalsContact O-CB 3.31Å; A668-C671 WeakPolarHBondContact O-CB 3.42Å; A668-C671 PolarHBondContact O-N 3.09Å; A668-C671 VanDerWaalsContact O-N 3.13Å; A668-D721 WeakPolarHBondContact CA-O 3.35Å; A668-V723 WeakPolarHBondContact O-CG1 3.46Å; A668-V828 HydrophobicContact CB-CG1 4.47Å
669A94Very high87.4Confident0 Ų035.4 Ų35.40%019%0.192CC..G310 helixtrans-66.6-32.1179.500000112.3C671 V672 H673 T710 Y713 D721 V723A669-C671 PolarHBondContact O-N 2.8Å; A669-V672 WeakPolarHBondContact O-CG2 3.49Å; A669-V672 PolarHBondContact O-N 2.92Å; A669-H673 PolarHBondContact O-N 2.99Å; A669-T710 HydrophobicContact CB-CG2 4.06Å; A669-Y713 HydrophobicContact CB-CD1 4.06Å; A669-Y713 HydrophobicContact CB-CD2 3.65Å; A669-Y713 HydrophobicContact CB-CE2 4.25Å; A669-Y713 HydrophobicContact CB-CG 3.53Å; A669-D721 WeakPolarHBondContact CA-OD1 3.47Å; A669-D721 PolarHBondContact N-OD1 3.47Å; A669-V723 HydrophobicContact CB-CB 4.46Å
670H92.9Very high88.7Confident44 Ų4431.2 Ų31.220%0.20417%0.167CC..G310 helixtrans-63-20.8174.678.6-104000113A668 V672 H673 Y713 D721 S811 S830A668-H670 VanDerWaalsContact C-N 3.3Å; A668-H670 WeakPolarHBondContact CB-ND1 3.31Å; A668-H670 PolarHBondContact O-N 3.32Å; H670-V672 PolarHBondContact O-N 3.26Å; H670-H673 PolarHBondContact O-N 3.19Å; H670-H673 VanDerWaalsContact O-O 3.13Å; H670-Y713 HydrophobicContact CB-CE1 4.48Å; H670-Y713 HydrophobicContact CB-CE2 4.4Å; H670-Y713 VanDerWaalsContact CB-OH 3.25Å; H670-Y713 WeakPolarHBondContact CB-OH 3.35Å; H670-D721 IonicContact CE1-OD2 3.89Å; H670-D721 IonicContact CG-OD1 4Å; H670-D721 IonicContact CG-OD2 3.24Å; H670-D721 PolarHBondContact N-OD1 2.78Å; H670-D721 IonicContact ND1-OD1 3.72Å; H670-D721 PolarHBondContact ND1-OD1 3.25Å; H670-D721 IonicContact ND1-OD2 2.8Å; H670-D721 PolarHBondContact ND1-OD2 2.8Å; H670-S811 PolarHBondContact CE1-OG 2.93Å; H670-S811 WeakPolarHBondContact NE2-CB 2.9Å; H670-S811 PolarHBondContact NE2-OG 3.12Å; H670-S830 PolarHBondContact CE1-O 2.77Å
671C93.8Very high89.9Confident9 Ų928 Ų286%0.06115%0.151CC..G310 helixtrans-71.5-18.3174.3-69.60000113C649 A668 A669 M679C649-C671 HydrophobicContact CB-CB 3.75Å; C649-C671 WeakPolarHBondContact CB-SG 3.35Å; C649-C671 WeakPolarHBondContact SG-CB 3.3Å; C649-C671 CovalentContact SG-SG 2.04Å; C649-C671 PolarHBondContact SG-SG 3.29Å; A668-C671 VanDerWaalsContact O-CB 3.31Å; A668-C671 WeakPolarHBondContact O-CB 3.42Å; A668-C671 PolarHBondContact O-N 3.09Å; A668-C671 VanDerWaalsContact O-N 3.13Å; A669-C671 PolarHBondContact O-N 2.8Å; C671-M679 WeakPolarHBondContact O-CE 3.46Å
672V92.6Very high90.4Very high1 Ų132.6 Ų32.61%0.00617%0.166CC..THydrogen-bonded Turntrans-108.20.2176.6-54.80000113.7A669 H670 Y678 M679 F684 Y708 T710 V723 L725A669-V672 WeakPolarHBondContact O-CG2 3.49Å; A669-V672 PolarHBondContact O-N 2.92Å; H670-V672 PolarHBondContact O-N 3.26Å; V672-Y678 HydrophobicContact CG2-CD1 4.21Å; V672-Y678 HydrophobicContact CG2-CE1 4.49Å; V672-M679 PolarHBondContact O-N 3.27Å; V672-F684 HydrophobicContact CB-CE1 4.33Å; V672-F684 HydrophobicContact CB-CZ 3.75Å; V672-F684 HydrophobicContact CG1-CE1 3.79Å; V672-F684 HydrophobicContact CG1-CE2 4.33Å; V672-F684 HydrophobicContact CG1-CZ 3.58Å; V672-Y708 HydrophobicContact CB-CE2 4.31Å; V672-Y708 HydrophobicContact CG2-CD2 4.32Å; V672-Y708 HydrophobicContact CG2-CE2 3.97Å; V672-T710 HydrophobicContact CG2-CG2 4Å; V672-V723 HydrophobicContact CG1-CG1 4.17Å; V672-V723 HydrophobicContact CG2-CB 4.42Å; V672-V723 HydrophobicContact CG2-CG1 4.36Å; V672-V723 HydrophobicContact CG2-CG2 4.12Å; V672-L725 HydrophobicContact CG1-CD2 4.05Å
673H89.4Confident90.6Very high27 Ų2733.6 Ų33.613%0.12517%0.172CC..EExtended strand (participates in β ladder)trans-117.5122.2-175.6-177.7-100.8000110.8A669 H670 N676 T677 Y678 Y713 D715A669-H673 PolarHBondContact O-N 2.99Å; H670-H673 PolarHBondContact O-N 3.19Å; H670-H673 VanDerWaalsContact O-O 3.13Å; H673-N676 WeakPolarHBondContact NE2-CA 3.24Å; H673-T677 CarbonylContact C-O 3.6Å; H673-T677 WeakPolarHBondContact CA-O 3.31Å; H673-T677 PolarHBondContact CD2-O 3.05Å; H673-Y678 HydrophobicContact CB-CD1 4.18Å; H673-Y678 HydrophobicContact CB-CE1 4.11Å; H673-Y678 AromaticContact CD2-CE1 3.93Å; H673-Y713 HydrophobicContact CB-CD1 4.35Å; H673-Y713 HydrophobicContact CB-CE1 4.01Å; H673-Y713 AromaticContact CG-CE1 3.96Å; H673-Y713 AromaticContact ND1-CE1 3.84Å; H673-D715 IonicContact CE1-OD1 2.71Å; H673-D715 IonicContact CE1-OD2 3.75Å; H673-D715 IonicContact ND1-OD1 2.68Å; H673-D715 PolarHBondContact ND1-OD1 3.48Å; H673-D715 IonicContact ND1-OD2 3.93Å
674Y83.5Confident90.7Very high105 Ų10533.4 Ų33.441%0.41217%0.171SC..EExtended strand (participates in β ladder)trans-142.6135.9179.3179.7-103.8000110.8E642 F647 N676 T677E642-Y674 HydrophobicContact CG-CD1 4.24Å; F647-Y674 AromaticContact CE1-CD2 3.98Å; F647-Y674 HydrophobicContact CE1-CD2 3.98Å; F647-Y674 AromaticContact CE1-CE2 3.92Å; F647-Y674 HydrophobicContact CE1-CE2 3.92Å; F647-Y674 AromaticContact CZ-CD2 3.79Å; F647-Y674 HydrophobicContact CZ-CD2 3.79Å; F647-Y674 HydrophobicContact CZ-CE1 4.43Å; F647-Y674 AromaticContact CZ-CE2 3.64Å; F647-Y674 HydrophobicContact CZ-CE2 3.64Å; F647-Y674 HydrophobicContact CZ-CG 4.26Å; F647-Y674 AromaticContact CZ-CZ 3.99Å; Y674-N676 PolarHBondContact O-N 3.26Å; Y674-T677 PolarHBondContact N-O 3.24Å; Y674-T677 CarbonylContact O-C 3.51Å; Y674-T677 PolarHBondContact O-N 3.37Å; Y674-T677 PolarHBondContact O-OG1 3.34Å
675G78.1Confident90.6Very high60 Ų6035.8 Ų35.862%0.61918%0.184SC*.THydrogen-bonded Turntrans61.236.6175.200000114.8T677G675-T677 PolarHBondContact O-N 2.96Å
676N76Confident90.5Very high118 Ų11835.8 Ų35.863%0.63118%0.184SC*.THydrogen-bonded Turntrans60.323.8-171.4-65.3-30.2000114.2H673 Y674H673-N676 WeakPolarHBondContact NE2-CA 3.24Å; Y674-N676 PolarHBondContact O-N 3.26Å
677T81.5Confident90.4Very high31 Ų3138.3 Ų38.319%0.1920%0.195CC..EExtended strand (participates in β ladder)trans-135.1152.1177.654.40000111.2H673 Y674 G675 K878H673-T677 CarbonylContact C-O 3.6Å; H673-T677 WeakPolarHBondContact CA-O 3.31Å; H673-T677 PolarHBondContact CD2-O 3.05Å; Y674-T677 PolarHBondContact N-O 3.24Å; Y674-T677 CarbonylContact O-C 3.51Å; Y674-T677 PolarHBondContact O-N 3.37Å; Y674-T677 PolarHBondContact O-OG1 3.34Å; G675-T677 PolarHBondContact O-N 2.96Å; T677-K878 HydrophobicContact CG2-CG 3.8Å
678Y87.7Confident90.4Very high93 Ų9338.4 Ų38.437%0.36520%0.195SC..EExtended strand (participates in β ladder)trans-86.6129.1172.4-72.8-70.8000110V672 H673 Y708 T710V672-Y678 HydrophobicContact CG2-CD1 4.21Å; V672-Y678 HydrophobicContact CG2-CE1 4.49Å; H673-Y678 HydrophobicContact CB-CD1 4.18Å; H673-Y678 HydrophobicContact CB-CE1 4.11Å; H673-Y678 AromaticContact CD2-CE1 3.93Å; Y678-Y708 WeakPolarHBondContact CB-OH 3.32Å; Y678-Y708 HydrophobicContact CD1-CE2 4.46Å; Y678-T710 HydrophobicContact CD1-CG2 4.47Å; Y678-T710 HydrophobicContact CE1-CG2 3.77Å; Y678-T710 PolarHBondContact OH-OG1 3.34Å
679M89.7Confident90.3Very high6 Ų638.6 Ų38.63%0.0320%0.197CC..PPolyproline II helixtrans-71.3147.1179.6-67.7-175-79.200111A640 E642 C671 V672 F684 Y708A640-M679 HydrophobicContact CB-CE 4.35Å; E642-M679 HydrophobicContact CB-CG 4.36Å; E642-M679 HydrophobicContact CB-SD 3.69Å; E642-M679 HydrophobicContact CG-CG 4.09Å; E642-M679 HydrophobicContact CG-SD 4.05Å; C671-M679 WeakPolarHBondContact O-CE 3.46Å; V672-M679 PolarHBondContact O-N 3.27Å; M679-F684 HydrophobicContact CB-CE2 3.97Å; M679-F684 HydrophobicContact CB-CZ 3.81Å; M679-F684 HydrophobicContact CE-CE1 4.01Å; M679-F684 HydrophobicContact CE-CZ 3.85Å; M679-Y708 WeakPolarHBondContact O-CE1 3.39Å; M679-Y708 PolarHBondContact O-OH 3.32Å
680S88.8Confident90.2Very high27 Ų2739 Ų3919%0.18920%0.2CC..PPolyproline II helixtrans-61.3142.6177.8176.80000111.5R682 S683 F684 T872S680-R682 PolarHBondContact O-N 2.86Å; S680-R682 PolarHBondContact OG-N 3.03Å; S680-S683 VanDerWaalsContact O-CB 3.24Å; S680-S683 WeakPolarHBondContact O-CB 3.46Å; S680-S683 PolarHBondContact O-N 3.38Å; S680-S683 PolarHBondContact O-OG 3.12Å; S680-F684 VanDerWaalsContact O-CD2 3.31Å; S680-F684 WeakPolarHBondContact O-CD2 3.2Å; S680-F684 VanDerWaalsContact O-CE2 3.23Å; S680-F684 WeakPolarHBondContact O-CE2 3.44Å; S680-T872 PolarHBondContact OG-O 3.48Å
681P92.3Very high90.3Very high8 Ų837.1 Ų37.15%0.05219%0.192CC..G310 helixtrans-50.9-28.6171.4-30.338000114S683 F684 V705 Y708 Q869P681-S683 PolarHBondContact O-N 3.2Å; P681-F684 PolarHBondContact O-N 3.14Å; P681-V705 HydrophobicContact CB-CB 4.33Å; P681-V705 HydrophobicContact CB-CG1 4.14Å; P681-Y708 HydrophobicContact CB-CD1 4.41Å; P681-Y708 HydrophobicContact CB-CE1 4.44Å; P681-Y708 HydrophobicContact CG-CD1 3.88Å; P681-Y708 HydrophobicContact CG-CE1 3.72Å; P681-Q869 HydrophobicContact CB-CB 4.48Å; P681-Q869 HydrophobicContact CG-CB 3.81Å
682R90.1Very high90.1Very high152 Ų15237.4 Ų37.457%0.57419%0.193SC*.G310 helixtrans-63.7-25.4174.9-172.4175.2174.5-176.4-1.3113.7S680 F684 S870S680-R682 PolarHBondContact O-N 2.86Å; S680-R682 PolarHBondContact OG-N 3.03Å; R682-F684 PolarHBondContact O-N 3.41Å; R682-S870 VanDerWaalsContact CB-O 3.32Å; R682-S870 WeakPolarHBondContact CB-O 3.28Å; R682-S870 WeakPolarHBondContact CG-O 3.34Å
683S91.7Very high89.9Confident20 Ų2039.9 Ų39.914%0.1421%0.206CC..G310 helixtrans-69.5-12.5-178.6-60.20000112.4A640 Y641 E642 S680 P681A640-S683 CarbonylContact C-O 3.59Å; A640-S683 WeakPolarHBondContact CA-O 3.25Å; Y641-S683 PolarHBondContact N-O 2.62Å; Y641-S683 VanDerWaalsContact O-CB 3.31Å; Y641-S683 WeakPolarHBondContact O-CB 3.09Å; Y641-S683 PolarHBondContact O-OG 2.86Å; E642-S683 PolarHBondContact OE2-OG 2.82Å; S680-S683 VanDerWaalsContact O-CB 3.24Å; S680-S683 WeakPolarHBondContact O-CB 3.46Å; S680-S683 PolarHBondContact O-N 3.38Å; S680-S683 PolarHBondContact O-OG 3.12Å; P681-S683 PolarHBondContact O-N 3.2Å
684F95Very high89.9Confident1 Ų145.3 Ų45.30%0.00424%0.235CC..EExtended strand (participates in β ladder)trans-107.1134.6-171.1-57.6-86.8000113.7I638 L639 A640 V672 M679 S680 P681 R682 I686 V705 Y708I638-F684 HydrophobicContact CG2-CD1 4.07Å; L639-F684 CarbonylContact O-C 3.22Å; L639-F684 WeakPolarHBondContact O-CA 3.48Å; A640-F684 HydrophobicContact CB-CD1 3.66Å; A640-F684 HydrophobicContact CB-CE1 3.7Å; V672-F684 HydrophobicContact CB-CE1 4.33Å; V672-F684 HydrophobicContact CB-CZ 3.75Å; V672-F684 HydrophobicContact CG1-CE1 3.79Å; V672-F684 HydrophobicContact CG1-CE2 4.33Å; V672-F684 HydrophobicContact CG1-CZ 3.58Å; M679-F684 HydrophobicContact CB-CE2 3.97Å; M679-F684 HydrophobicContact CB-CZ 3.81Å; M679-F684 HydrophobicContact CE-CE1 4.01Å; M679-F684 HydrophobicContact CE-CZ 3.85Å; S680-F684 VanDerWaalsContact O-CD2 3.31Å; S680-F684 WeakPolarHBondContact O-CD2 3.2Å; S680-F684 VanDerWaalsContact O-CE2 3.23Å; S680-F684 WeakPolarHBondContact O-CE2 3.44Å; P681-F684 PolarHBondContact O-N 3.14Å; R682-F684 PolarHBondContact O-N 3.41Å; F684-I686 HydrophobicContact CB-CD1 4.44Å; F684-V705 HydrophobicContact CB-CB 4.39Å; F684-V705 HydrophobicContact CB-CG2 3.69Å; F684-V705 HydrophobicContact CG-CG2 4.46Å; F684-Y708 HydrophobicContact CE2-CE1 4.07Å
685L94.9Very high90Very high50 Ų5046.1 Ų46.126%0.26224%0.241SC..EExtended strand (participates in β ladder)trans-118.8125.8167.4-67.7173.1000109.5L639 Y641 F687L639-L685 HydrophobicContact CB-CB 4.37Å; L639-L685 PolarHBondContact N-O 3.32Å; L639-L685 PolarHBondContact O-N 3.05Å; Y641-L685 HydrophobicContact CE2-CD1 4.31Å; L685-F687 HydrophobicContact CB-CE2 3.89Å; L685-F687 HydrophobicContact CB-CZ 4.49Å
686I97.3Very high90.3Very high0 Ų055.6 Ų55.60%026%0.258CS..EExtended strand (participates in β ladder)trans-107.1116.4-174.7-51.2-57.3000109.5V636 I638 V665 F684 L688 Y702 R703 V705 L725 L727V636-I686 HydrophobicContact CG1-CG2 3.28Å; I638-I686 HydrophobicContact CB-CD1 4.4Å; I638-I686 HydrophobicContact CD1-CD1 4.43Å; I638-I686 HydrophobicContact CG1-CD1 3.97Å; I638-I686 HydrophobicContact CG2-CD1 3.98Å; V665-I686 HydrophobicContact CG2-CG2 4.25Å; F684-I686 HydrophobicContact CB-CD1 4.44Å; I686-L688 HydrophobicContact CG2-CD1 3.94Å; I686-L688 HydrophobicContact CG2-CG 4.46Å; I686-Y702 CarbonylContact O-C 3.56Å; I686-Y702 WeakPolarHBondContact O-CA 3.43Å; I686-R703 HydrophobicContact CB-CB 4.45Å; I686-R703 WeakPolarHBondContact CB-O 3.4Å; I686-R703 PolarHBondContact N-O 2.99Å; I686-R703 PolarHBondContact O-N 2.92Å; I686-V705 HydrophobicContact CD1-CG2 3.75Å; I686-V705 HydrophobicContact CG1-CG2 3.58Å; I686-L725 HydrophobicContact CD1-CD1 3.91Å; I686-L727 HydrophobicContact CB-CD2 4.03Å; I686-L727 HydrophobicContact CG1-CD2 3.79Å; I686-L727 HydrophobicContact CG2-CD2 3.99Å
687F96.1Very high90.8Very high53 Ų5352 Ų5223%0.23224%0.238CC..EExtended strand (participates in β ladder)trans-102.5129.9178.8-64.8-97.2000110.8V636 H637 L639 L685 I700 I701V636-F687 WeakPolarHBondContact CA-O 3.08Å; H637-F687 HydrophobicContact CB-CB 4.21Å; H637-F687 PolarHBondContact N-O 2.98Å; H637-F687 PolarHBondContact O-N 2.84Å; L639-F687 HydrophobicContact CB-CD2 4.48Å; L639-F687 HydrophobicContact CB-CE2 3.99Å; L639-F687 HydrophobicContact CD2-CE2 3.94Å; L639-F687 HydrophobicContact CD2-CZ 4.41Å; L685-F687 HydrophobicContact CB-CE2 3.89Å; L685-F687 HydrophobicContact CB-CZ 4.49Å; F687-I700 HydrophobicContact CD1-CG2 4.13Å; F687-I701 WeakPolarHBondContact CA-O 2.97Å
688L96.5Very high90.9Very high2 Ų260.1 Ų60.11%0.0127%0.274CS..EExtended strand (participates in β ladder)trans-127.7155178.6-54.497.9000110.5V636 L653 I686 A690 I700 I701 R703 L727 V731 I737V636-L688 HydrophobicContact CG2-CD2 3.92Å; V636-L688 HydrophobicContact CG2-CG 4.13Å; L653-L688 HydrophobicContact CB-CD2 4.46Å; L653-L688 HydrophobicContact CD1-CD2 4.05Å; L653-L688 HydrophobicContact CD2-CD2 4.37Å; I686-L688 HydrophobicContact CG2-CD1 3.94Å; I686-L688 HydrophobicContact CG2-CG 4.46Å; L688-A690 VanDerWaalsContact C-N 3.25Å; L688-A690 PolarHBondContact O-N 3.01Å; L688-I700 WeakPolarHBondContact O-CA 3.4Å; L688-I701 HydrophobicContact CB-CD1 4.45Å; L688-I701 HydrophobicContact CB-CG1 3.99Å; L688-I701 HydrophobicContact CD1-CD1 4.46Å; L688-I701 HydrophobicContact CD1-CG1 4.26Å; L688-I701 PolarHBondContact N-O 2.87Å; L688-I701 PolarHBondContact O-N 2.91Å; L688-R703 HydrophobicContact CD1-CG 4.24Å; L688-L727 HydrophobicContact CD1-CD1 4.48Å; L688-V731 HydrophobicContact CD1-CG2 4.12Å; L688-V731 HydrophobicContact CD2-CG1 4.48Å; L688-V731 HydrophobicContact CD2-CG2 4.32Å; L688-I737 HydrophobicContact CB-CD1 4.01Å; L688-I737 HydrophobicContact CB-CG1 4.36Å; L688-I737 HydrophobicContact CB-CG2 4.46Å; L688-I737 HydrophobicContact CD2-CG2 4.31Å
689G94.2Very high90.9Very high3 Ų357 Ų573%0.03127%0.265CS..SBendtrans75.411.6177.800000114.5N630 S699N630-G689 PolarHBondContact ND2-O 3.46Å; G689-S699 VanDerWaalsContact O-CB 3.32Å; G689-S699 WeakPolarHBondContact O-CB 3.21Å; G689-S699 PolarHBondContact O-OG 2.99Å
690A93Very high91.1Very high9 Ų958.9 Ų58.97%0.07428%0.275CS..  trans-86.2141177.300000111.9L688 L693 I700 W760L688-A690 VanDerWaalsContact C-N 3.25Å; L688-A690 PolarHBondContact O-N 3.01Å; A690-L693 HydrophobicContact CB-CD2 3.88Å; A690-I700 HydrophobicContact CB-CD1 3.87Å; A690-I700 HydrophobicContact CB-CG1 3.67Å; A690-W760 HydrophobicContact CB-CZ2 4.41Å; A690-W760 WeakPolarHBondContact O-CZ2 3.35Å
691H93.4Very high91.3Very high5 Ų559.8 Ų59.82%0.02328%0.277CS..SBendtrans-110.8-55162.1175.869.2000110.3E626 A627 P629 E697 W760 A771 L772E626-H691 IonicContact OE1-CD2 3.85Å; E626-H691 IonicContact OE1-CE1 2.76Å; E626-H691 IonicContact OE1-NE2 3.56Å; E626-H691 PolarHBondContact OE1-NE2 2.77Å; A627-H691 PolarHBondContact O-CE1 3.19Å; P629-H691 HydrophobicContact CB-CB 4.38Å; H691-E697 WeakPolarHBondContact CB-OE1 3.43Å; H691-E697 PolarHBondContact N-OE2 3.23Å; H691-W760 PolarHBondContact O-NE1 3.01Å; H691-A771 CarbonylContact O-C 3.54Å; H691-A771 WeakPolarHBondContact O-CA 3.05Å; H691-L772 PolarHBondContact O-N 3.37Å
692D90.6Very high91.3Very high14 Ų1466.6 Ų66.68%0.07530%0.303CS..BIsolated β-bridgetrans-110.5109.3176.8-171.3-26.5000111.8N694 K695 E697 A770D692-N694 PolarHBondContact O-N 3.21Å; D692-N694 PolarHBondContact OD1-N 3.04Å; D692-K695 HydrophobicContact CB-CB 4.15Å; D692-K695 HydrophobicContact CB-CD 3.95Å; D692-K695 HydrophobicContact CB-CG 4.07Å; D692-K695 PolarHBondContact O-N 2.78Å; D692-K695 VanDerWaalsContact O-N 3.07Å; D692-K695 WeakPolarHBondContact OD2-CD 2.99Å; D692-K695 WeakPolarHBondContact OD2-CE 3.46Å; D692-K695 IonicContact OD2-NZ 3.27Å; D692-K695 PolarHBondContact OD2-NZ 3.4Å; D692-E697 PolarHBondContact N-OE1 3.01Å; D692-E697 PolarHBondContact N-OE2 3.17Å; D692-A770 CarbonylContact C-O 3.47Å; D692-A770 VanDerWaalsContact CA-O 3.3Å; D692-A770 WeakPolarHBondContact CA-O 3.02Å; D692-A770 WeakPolarHBondContact OD1-CB 3.16Å
693L88.5Confident91.6Very high54 Ų5462.2 Ų62.228%0.28329%0.286SS..THydrogen-bonded Turntrans-66.4-15.4-177.1-63176.7000114H637 A690 W760 A770H637-L693 HydrophobicContact CB-CD2 4.16Å; A690-L693 HydrophobicContact CB-CD2 3.88Å; L693-W760 HydrophobicContact CD1-CB 3.81Å; L693-W760 HydrophobicContact CD1-CD2 4.06Å; L693-W760 HydrophobicContact CD1-CG 3.55Å; L693-W760 HydrophobicContact CG-CD2 4.45Å; L693-W760 HydrophobicContact CG-CG 4.13Å; L693-A770 PolarHBondContact N-O 3.36Å
694N88.3Confident91.7Very high140 Ų14064.5 Ų64.575%0.74930%0.297SS*.THydrogen-bonded Turntrans-92.9-7.5175.8-73.4-17.9000112.9D692 A770D692-N694 PolarHBondContact O-N 3.21Å; D692-N694 PolarHBondContact OD1-N 3.04Å; N694-A770 HydrophobicContact CB-CB 4.09Å; N694-A770 VanDerWaalsContact ND2-CB 3.27Å; N694-A770 WeakPolarHBondContact ND2-CB 3.49Å
695K86.4Confident91.8Very high122 Ų12264.4 Ų64.453%0.5330%0.296SS..SBendtrans-103144.7178.7-67.9-178.4-177.1127.20110.8D692 E697D692-K695 HydrophobicContact CB-CB 4.15Å; D692-K695 HydrophobicContact CB-CD 3.95Å; D692-K695 HydrophobicContact CB-CG 4.07Å; D692-K695 PolarHBondContact O-N 2.78Å; D692-K695 VanDerWaalsContact O-N 3.07Å; D692-K695 WeakPolarHBondContact OD2-CD 2.99Å; D692-K695 WeakPolarHBondContact OD2-CE 3.46Å; D692-K695 IonicContact OD2-NZ 3.27Å; D692-K695 PolarHBondContact OD2-NZ 3.4Å; K695-E697 VanDerWaalsContact C-N 3.29Å; K695-E697 HydrophobicContact CB-CG 4.06Å; K695-E697 PolarHBondContact O-N 3.27Å
696R83.4Confident91.7Very high260 Ų26065.5 Ų65.598%0.98130%0.297SS*.  trans-80.180.4167.6-72.7-174.1174.9-175.6-1.2109.3
697E87.1Confident91.5Very high42 Ų4265.7 Ų65.720%0.19630%0.298CS..  trans-80.4135.1174.4-58174.1156.800110H691 D692 K695 S699 I700H691-E697 WeakPolarHBondContact CB-OE1 3.43Å; H691-E697 PolarHBondContact N-OE2 3.23Å; D692-E697 PolarHBondContact N-OE1 3.01Å; D692-E697 PolarHBondContact N-OE2 3.17Å; K695-E697 VanDerWaalsContact C-N 3.29Å; K695-E697 HydrophobicContact CB-CG 4.06Å; K695-E697 PolarHBondContact O-N 3.27Å; E697-S699 PolarHBondContact O-N 3.04Å; E697-I700 HydrophobicContact CB-CD1 3.76Å; E697-I700 HydrophobicContact CB-CG1 3.91Å; E697-I700 HydrophobicContact CG-CD1 4.18Å; E697-I700 PolarHBondContact O-N 2.85Å
698Q84.6Confident91.5Very high202 Ų20264.8 Ų64.894%0.94429%0.293SS*.THydrogen-bonded Turntrans-64.9-20.4-179.3-68-179.6-5.100113.1I700Q698-I700 VanDerWaalsContact C-N 3.34Å
699S88Confident91.3Very high26 Ų2666.8 Ų66.818%0.18231%0.305CS..THydrogen-bonded Turntrans-78.1-16.5178.553.80000113.8G689 E697 I701G689-S699 VanDerWaalsContact O-CB 3.32Å; G689-S699 WeakPolarHBondContact O-CB 3.21Å; G689-S699 PolarHBondContact O-OG 2.99Å; E697-S699 PolarHBondContact O-N 3.04Å; S699-I701 PolarHBondContact O-N 3.25Å
700I92Very high91.1Very high47 Ų4768.1 Ų68.124%0.24131%0.313CS..  trans-73.3126.6-176.1-65.4170.1000109.9F687 L688 A690 E697 Q698F687-I700 HydrophobicContact CD1-CG2 4.13Å; L688-I700 WeakPolarHBondContact O-CA 3.4Å; A690-I700 HydrophobicContact CB-CD1 3.87Å; A690-I700 HydrophobicContact CB-CG1 3.67Å; E697-I700 HydrophobicContact CB-CD1 3.76Å; E697-I700 HydrophobicContact CB-CG1 3.91Å; E697-I700 HydrophobicContact CG-CD1 4.18Å; E697-I700 PolarHBondContact O-N 2.85Å; Q698-I700 VanDerWaalsContact C-N 3.34Å
701I93.1Very high90.6Very high45 Ų4568.2 Ų68.223%0.23131%0.312CS..EExtended strand (participates in β ladder)trans-124155.4168.167.6171.8000109.8F687 L688 S699 V731 I737F687-I701 WeakPolarHBondContact CA-O 2.97Å; L688-I701 HydrophobicContact CB-CD1 4.45Å; L688-I701 HydrophobicContact CB-CG1 3.99Å; L688-I701 HydrophobicContact CD1-CD1 4.46Å; L688-I701 HydrophobicContact CD1-CG1 4.26Å; L688-I701 PolarHBondContact N-O 2.87Å; L688-I701 PolarHBondContact O-N 2.91Å; S699-I701 PolarHBondContact O-N 3.25Å; I701-V731 HydrophobicContact CD1-CB 4.2Å; I701-V731 HydrophobicContact CD1-CG1 3.42Å; I701-V731 VanDerWaalsContact CD1-CG1 3.42Å; I701-V731 HydrophobicContact CD1-CG2 3.81Å; I701-I737 HydrophobicContact CD1-CD1 3.59Å; I701-I737 HydrophobicContact CG1-CD1 3.76Å
702Y93.7Very high89.9Confident152 Ų15271.6 Ų71.660%0.59633%0.327SS*.EExtended strand (participates in β ladder)trans-117.1152.9169.469.8-87.4000111.4I686I686-Y702 CarbonylContact O-C 3.56Å; I686-Y702 WeakPolarHBondContact O-CA 3.43Å
703R96.1Very high89.5Confident60 Ų6071.3 Ų71.323%0.22633%0.325CS..EExtended strand (participates in β ladder)trans-139.2141.6175.3-68.5-64.9-176.9-90.62.4110.7I686 L688 L727 L729 V731I686-R703 HydrophobicContact CB-CB 4.45Å; I686-R703 WeakPolarHBondContact CB-O 3.4Å; I686-R703 PolarHBondContact N-O 2.99Å; I686-R703 PolarHBondContact O-N 2.92Å; L688-R703 HydrophobicContact CD1-CG 4.24Å; R703-L727 HydrophobicContact CB-CB 4.34Å; R703-L727 HydrophobicContact CB-CD1 4.17Å; R703-L727 HydrophobicContact CB-CD2 4.13Å; R703-L727 HydrophobicContact CB-CG 4.44Å; R703-L727 HydrophobicContact CG-CD1 4.17Å; R703-L729 WeakPolarHBondContact CD-O 3.29Å; R703-L729 PolarHBondContact NE-O 3.31Å; R703-V731 HydrophobicContact CG-CG2 3.79Å
704D94Very high89Confident67 Ų6769.3 Ų69.336%0.35832%0.315SS..EExtended strand (participates in β ladder)trans-79154.2168.5-55.7-41000110.3K728D704-K728 HydrophobicContact CB-CB 4.24Å; D704-K728 HydrophobicContact CB-CD 4.27Å; D704-K728 PolarHBondContact O-N 2.81Å
705V95.8Very high88.5Confident0 Ų065.6 Ų65.60%030%0.295CS..EExtended strand (participates in β ladder)trans-88.5126.2172.3-1780000109.8P681 F684 I686 N707 Y708 L725 S870P681-V705 HydrophobicContact CB-CB 4.33Å; P681-V705 HydrophobicContact CB-CG1 4.14Å; F684-V705 HydrophobicContact CB-CB 4.39Å; F684-V705 HydrophobicContact CB-CG2 3.69Å; F684-V705 HydrophobicContact CG-CG2 4.46Å; I686-V705 HydrophobicContact CD1-CG2 3.75Å; I686-V705 HydrophobicContact CG1-CG2 3.58Å; V705-N707 WeakPolarHBondContact CG1-O 3.42Å; V705-Y708 HydrophobicContact CG1-CD1 4.4Å; V705-L725 HydrophobicContact CG1-CB 4.23Å; V705-L725 HydrophobicContact CG2-CD1 4.34Å; V705-S870 VanDerWaalsContact O-CB 3.28Å; V705-S870 WeakPolarHBondContact O-CB 3.24Å
706R93.5Very high87.9Confident73 Ų7367 Ų6728%0.27530%0.304SS..EExtended strand (participates in β ladder)trans-73.7-52.8175.3-179.4-176.9168.1121.9-4.6110.9R726 K728 A866 D868 Q869 S870R706-R726 WeakPolarHBondContact CB-O 3.42Å; R706-R726 PolarHBondContact N-O 2.87Å; R706-K728 HydrophobicContact CB-CB 4.49Å; R706-A866 PolarHBondContact NH2-O 3.22Å; R706-D868 HydrophobicContact CG-CB 3.84Å; R706-Q869 CarbonylContact O-C 3.57Å; R706-Q869 WeakPolarHBondContact O-CA 3.26Å; R706-Q869 PolarHBondContact O-N 3.46Å; R706-S870 PolarHBondContact O-N 3.07Å
707N93.3Very high87.4Confident3 Ų358 Ų582%0.01627%0.272CS..EExtended strand (participates in β ladder)trans-164.9169-178.452.333.1000109V705 R726 L863 A866 P867V705-N707 WeakPolarHBondContact CG1-O 3.42Å; N707-R726 PolarHBondContact O-N 2.95Å; N707-R726 WeakPolarHBondContact OD1-CB 3.43Å; N707-L863 HydrophobicContact CB-CD2 4.45Å; N707-L863 PolarHBondContact ND2-O 3.41Å; N707-L863 WeakPolarHBondContact OD1-CD2 3.07Å; N707-A866 WeakPolarHBondContact ND2-CB 3.17Å; N707-A866 PolarHBondContact ND2-O 3.35Å; N707-P867 PolarHBondContact ND2-O 2.69Å
708Y95.5Very high86.8Confident35 Ų3559.5 Ų59.514%0.13728%0.279CS..EExtended strand (participates in β ladder)trans-150.8160.4177.263.1-104.8000112.2V672 Y678 M679 P681 F684 V705 V723 L724 L725V672-Y708 HydrophobicContact CB-CE2 4.31Å; V672-Y708 HydrophobicContact CG2-CD2 4.32Å; V672-Y708 HydrophobicContact CG2-CE2 3.97Å; Y678-Y708 WeakPolarHBondContact CB-OH 3.32Å; Y678-Y708 HydrophobicContact CD1-CE2 4.46Å; M679-Y708 WeakPolarHBondContact O-CE1 3.39Å; M679-Y708 PolarHBondContact O-OH 3.32Å; P681-Y708 HydrophobicContact CB-CD1 4.41Å; P681-Y708 HydrophobicContact CB-CE1 4.44Å; P681-Y708 HydrophobicContact CG-CD1 3.88Å; P681-Y708 HydrophobicContact CG-CE1 3.72Å; F684-Y708 HydrophobicContact CE2-CE1 4.07Å; V705-Y708 HydrophobicContact CG1-CD1 4.4Å; Y708-V723 HydrophobicContact CD2-CG2 3.82Å; Y708-V723 HydrophobicContact CG-CG2 4.18Å; Y708-L724 WeakPolarHBondContact CA-O 3.45Å; Y708-L724 VanDerWaalsContact CB-O 3.24Å; Y708-L724 WeakPolarHBondContact CB-O 3.46Å; Y708-L725 VanDerWaalsContact CB-CD2 3.44Å; Y708-L725 HydrophobicContact CD1-CD2 4.24Å; Y708-L725 HydrophobicContact CG-CD2 3.98Å
709V92.1Very high86.7Confident43 Ų4350.1 Ų50.126%0.26124%0.235SC..EExtended strand (participates in β ladder)trans-136.1128.8178.4168.30000109.7V723 L724 W855 T859 L863V709-V723 WeakPolarHBondContact O-CA 3.4Å; V709-V723 VanDerWaalsContact O-CG2 3.31Å; V709-V723 WeakPolarHBondContact O-CG2 3.43Å; V709-L724 PolarHBondContact N-O 3.14Å; V709-L724 VanDerWaalsContact N-O 3.09Å; V709-L724 PolarHBondContact O-N 3.46Å; V709-W855 HydrophobicContact CG1-CZ2 4.39Å; V709-T859 HydrophobicContact CB-CG2 3.59Å; V709-T859 HydrophobicContact CG1-CG2 3.65Å; V709-T859 HydrophobicContact CG2-CG2 4.27Å; V709-L863 HydrophobicContact CB-CD2 4.21Å; V709-L863 HydrophobicContact CG2-CD2 3.66Å; V709-L863 HydrophobicContact CG2-CG 4.14Å
710T90.8Very high86.6Confident32 Ų3249.3 Ų49.320%0.19623%0.229CC..EExtended strand (participates in β ladder)trans-97.6159.8171.765.90000110.5A669 V672 Y678 V723A669-T710 HydrophobicContact CB-CG2 4.06Å; V672-T710 HydrophobicContact CG2-CG2 4Å; Y678-T710 HydrophobicContact CD1-CG2 4.47Å; Y678-T710 HydrophobicContact CE1-CG2 3.77Å; Y678-T710 PolarHBondContact OH-OG1 3.34Å; T710-V723 HydrophobicContact CG2-CB 3.98Å; T710-V723 HydrophobicContact CG2-CG2 3.72Å
711H83.4Confident86.6Confident10 Ų1047.1 Ų47.15%0.04622%0.217CC..SBendtrans-104.582.8176.9-164.317.8000112.7Y713 N720 I722 Y852 W855 Y915H711-Y713 PolarHBondContact O-N 3.29Å; H711-Y713 VanDerWaalsContact O-N 3.11Å; H711-N720 WeakPolarHBondContact O-CB 3.41Å; H711-I722 HydrophobicContact CB-CG2 4.13Å; H711-I722 PolarHBondContact N-O 2.81Å; H711-Y852 HydrophobicContact CB-CE1 4.47Å; H711-Y852 AromaticContact CD2-CD1 3.65Å; H711-Y852 AromaticContact CD2-CE1 3.48Å; H711-Y852 VanDerWaalsContact CD2-CE1 3.48Å; H711-Y852 WeakPolarHBondContact CD2-CE1 3.29Å; H711-W855 HydrophobicContact CB-CD2 4.1Å; H711-W855 HydrophobicContact CB-CH2 4.15Å; H711-W855 HydrophobicContact CB-CZ2 3.58Å; H711-W855 AromaticContact CD2-CD1 3.85Å; H711-W855 AromaticContact CD2-CG 3.84Å; H711-W855 AromaticContact CE1-CD1 3.81Å; H711-W855 AromaticContact CG-CD1 3.76Å; H711-W855 AromaticContact CG-CE2 3.76Å; H711-W855 AromaticContact CG-NE1 3.54Å; H711-W855 AromaticContact ND1-CD1 3.71Å; H711-W855 AromaticContact ND1-NE1 3.6Å; H711-W855 AromaticContact NE2-CD1 3.91Å; H711-Y915 AromaticContact NE2-CE1 3.64Å; H711-Y915 AromaticContact NE2-CZ 3.69Å
712F78.8Confident86.7Confident77 Ų7745 Ų4534%0.33821%0.206SC..SBendtrans47.444.9177.9-52.9-66.7000113.5S714 N720F712-S714 PolarHBondContact O-N 2.99Å; F712-N720 PolarHBondContact O-ND2 3.41Å
713Y81.1Confident86.8Confident8 Ų837.7 Ų37.73%0.03118%0.178CC..  trans-60.1131.8-175.7171.5-117.8000111.7A669 H670 H673 H711 D715 D719 D721A669-Y713 HydrophobicContact CB-CD1 4.06Å; A669-Y713 HydrophobicContact CB-CD2 3.65Å; A669-Y713 HydrophobicContact CB-CE2 4.25Å; A669-Y713 HydrophobicContact CB-CG 3.53Å; H670-Y713 HydrophobicContact CB-CE1 4.48Å; H670-Y713 HydrophobicContact CB-CE2 4.4Å; H670-Y713 VanDerWaalsContact CB-OH 3.25Å; H670-Y713 WeakPolarHBondContact CB-OH 3.35Å; H673-Y713 HydrophobicContact CB-CD1 4.35Å; H673-Y713 HydrophobicContact CB-CE1 4.01Å; H673-Y713 AromaticContact CG-CE1 3.96Å; H673-Y713 AromaticContact ND1-CE1 3.84Å; H711-Y713 PolarHBondContact O-N 3.29Å; H711-Y713 VanDerWaalsContact O-N 3.11Å; Y713-D715 HydrophobicContact CE1-CB 3.86Å; Y713-D715 WeakPolarHBondContact OH-CA 3.43Å; Y713-D715 PolarHBondContact OH-OD1 2.03Å; Y713-D719 WeakPolarHBondContact CD2-O 3.38Å; Y713-D721 HydrophobicContact CD2-CB 4.15Å; Y713-D721 HydrophobicContact CE2-CB 3.91Å; Y713-D721 WeakPolarHBondContact CE2-OD1 3.42Å
714S78.9Confident86.9Confident11 Ų1134.9 Ų34.98%0.07717%0.167CC..BIsolated β-bridgetrans-112104.7175.5-176.80000110.8F712 Q716 K717 H718 D719F712-S714 PolarHBondContact O-N 2.99Å; S714-Q716 PolarHBondContact O-N 3.02Å; S714-K717 PolarHBondContact O-N 3.29Å; S714-H718 WeakPolarHBondContact O-CA 3.46Å; S714-H718 PolarHBondContact O-N 3.45Å; S714-D719 PolarHBondContact N-O 3.11Å; S714-D719 PolarHBondContact O-N 3.43Å
715D76.3Confident87Confident62 Ų6231.7 Ų31.733%0.33215%0.15SC..THydrogen-bonded Turntrans-63-40.6-177.4-163.856.8000113.1H673 Y713 K717H673-D715 IonicContact CE1-OD1 2.71Å; H673-D715 IonicContact CE1-OD2 3.75Å; H673-D715 IonicContact ND1-OD1 2.68Å; H673-D715 PolarHBondContact ND1-OD1 3.48Å; H673-D715 IonicContact ND1-OD2 3.93Å; Y713-D715 HydrophobicContact CE1-CB 3.86Å; Y713-D715 WeakPolarHBondContact OH-CA 3.43Å; Y713-D715 PolarHBondContact OH-OD1 2.03Å; D715-K717 PolarHBondContact O-N 3.28Å
716Q73.5Confident87.1Confident152 Ų15232.9 Ų32.971%0.7116%0.155SC*.THydrogen-bonded Turntrans-63.7-30.2178.2-65.4-177.53.700113S714S714-Q716 PolarHBondContact O-N 3.02Å
717K73.4Confident87.2Confident71 Ų7129.5 Ų29.531%0.30914%0.142SC..THydrogen-bonded Turntrans-104.4-13.3-173.7-73.6178-172.51650112.7S714 D715 D719 R790 D907S714-K717 PolarHBondContact O-N 3.29Å; D715-K717 PolarHBondContact O-N 3.28Å; K717-D719 HydrophobicContact CB-CB 4Å; K717-D719 PolarHBondContact O-N 2.72Å; K717-R790 PolarHBondContact O-NH1 2.82Å; K717-R790 PolarHBondContact O-NH2 3.02Å; K717-D907 VanDerWaalsContact NZ-CG 3.29Å; K717-D907 IonicContact NZ-OD1 3.32Å; K717-D907 PolarHBondContact NZ-OD1 3.27Å; K717-D907 IonicContact NZ-OD2 3.36Å; K717-D907 PolarHBondContact NZ-OD2 3.21Å
718H74Confident87.1Confident74 Ų7433 Ų3334%0.34316%0.157SC..THydrogen-bonded Turntrans45.145-161.9-58.5-64.8000111.5S714S714-H718 WeakPolarHBondContact O-CA 3.46Å; S714-H718 PolarHBondContact O-N 3.45Å
719D82.5Confident86.9Confident4 Ų436.6 Ų36.62%0.02118%0.178CC..BIsolated β-bridgetrans-103.4147.4178.4-157.44000109.9Y713 S714 K717 D721 R790 R793 H916Y713-D719 WeakPolarHBondContact CD2-O 3.38Å; S714-D719 PolarHBondContact N-O 3.11Å; S714-D719 PolarHBondContact O-N 3.43Å; K717-D719 HydrophobicContact CB-CB 4Å; K717-D719 PolarHBondContact O-N 2.72Å; D719-D721 PolarHBondContact O-N 2.83Å; D719-R790 IonicContact OD2-NE 3.8Å; D719-R793 IonicContact OD1-CZ 2.79Å; D719-R793 IonicContact OD1-NE 3.91Å; D719-R793 PolarHBondContact OD1-NE 3.41Å; D719-R793 IonicContact OD1-NH2 3.91Å; D719-R793 IonicContact OD2-CZ 2.67Å; D719-R793 IonicContact OD2-NE 3.5Å; D719-R793 PolarHBondContact OD2-NE 2.74Å; D719-R793 IonicContact OD2-NH2 3.57Å; D719-R793 PolarHBondContact OD2-NH2 2.82Å; D719-H916 IonicContact OD2-CE1 2.77Å; D719-H916 PolarHBondContact OD2-CE1 2.77Å
720N86.8Confident86.8Confident10 Ų1036.7 Ų36.75%0.05318%0.179CC..SBendtrans48.143.7-169.7-52.1-49.4000113.7H711 F712 I722 R793 Y852H711-N720 WeakPolarHBondContact O-CB 3.41Å; F712-N720 PolarHBondContact O-ND2 3.41Å; N720-I722 PolarHBondContact O-N 2.74Å; N720-R793 WeakPolarHBondContact OD1-CD 3.47Å; N720-Y852 HydrophobicContact CB-CE1 4.43Å; N720-Y852 PolarHBondContact OD1-OH 3.37Å
721D92.5Very high86.6Confident0 Ų035.1 Ų35.10%017%0.17CC..  trans-7763.1-175.9-171.618.6000112.5A668 A669 H670 Y713 D719 S830 V847A668-D721 WeakPolarHBondContact CA-O 3.35Å; A669-D721 WeakPolarHBondContact CA-OD1 3.47Å; A669-D721 PolarHBondContact N-OD1 3.47Å; H670-D721 IonicContact CE1-OD2 3.89Å; H670-D721 IonicContact CG-OD1 4Å; H670-D721 IonicContact CG-OD2 3.24Å; H670-D721 PolarHBondContact N-OD1 2.78Å; H670-D721 IonicContact ND1-OD1 3.72Å; H670-D721 PolarHBondContact ND1-OD1 3.25Å; H670-D721 IonicContact ND1-OD2 2.8Å; H670-D721 PolarHBondContact ND1-OD2 2.8Å; Y713-D721 HydrophobicContact CD2-CB 4.15Å; Y713-D721 HydrophobicContact CE2-CB 3.91Å; Y713-D721 WeakPolarHBondContact CE2-OD1 3.42Å; D719-D721 PolarHBondContact O-N 2.83Å; D721-S830 VanDerWaalsContact CB-OG 3.3Å; D721-S830 WeakPolarHBondContact CB-OG 3.16Å; D721-S830 WeakPolarHBondContact OD2-CA 3.08Å; D721-S830 VanDerWaalsContact OD2-CB 3.26Å; D721-S830 WeakPolarHBondContact OD2-CB 3.35Å; D721-S830 PolarHBondContact OD2-OG 2.97Å; D721-V847 HydrophobicContact CB-CG2 4.21Å; D721-V847 WeakPolarHBondContact O-CG2 3.21Å
722I94.8Very high86.8Confident0 Ų043.5 Ų43.50%020%0.201CC..  trans-141.3140-176.8-171.1168.4000111.5V666 H711 N720 V828 V847 M849 Y852 W855V666-I722 HydrophobicContact CG1-CD1 4.1Å; V666-I722 HydrophobicContact CG1-CG1 4.08Å; H711-I722 HydrophobicContact CB-CG2 4.13Å; H711-I722 PolarHBondContact N-O 2.81Å; N720-I722 PolarHBondContact O-N 2.74Å; I722-V828 HydrophobicContact CD1-CG2 4Å; I722-V828 HydrophobicContact CG1-CG2 4.33Å; I722-V847 HydrophobicContact CB-CG1 4.36Å; I722-V847 HydrophobicContact CD1-CG1 4.46Å; I722-M849 HydrophobicContact CD1-CE 4.05Å; I722-M849 HydrophobicContact CD1-SD 3.82Å; I722-Y852 HydrophobicContact CG2-CD1 3.7Å; I722-Y852 HydrophobicContact CG2-CE1 3.73Å; I722-W855 HydrophobicContact CB-CZ3 4.44Å; I722-W855 HydrophobicContact CD1-CZ3 3.77Å; I722-W855 HydrophobicContact CG1-CH2 4.19Å; I722-W855 HydrophobicContact CG1-CZ3 3.83Å; I722-W855 HydrophobicContact CG2-CH2 3.94Å; I722-W855 HydrophobicContact CG2-CZ3 3.81Å
723V95.8Very high87Confident0 Ų040.3 Ų40.30%019%0.187CC..EExtended strand (participates in β ladder)trans-140.714117666.10000110.5T667 A668 A669 V672 Y708 V709 T710 L725T667-V723 HydrophobicContact CG2-CG1 3.32Å; T667-V723 PolarHBondContact N-O 3.4Å; T667-V723 VanDerWaalsContact N-O 3.15Å; T667-V723 PolarHBondContact O-N 3.01Å; A668-V723 WeakPolarHBondContact O-CG1 3.46Å; A669-V723 HydrophobicContact CB-CB 4.46Å; V672-V723 HydrophobicContact CG1-CG1 4.17Å; V672-V723 HydrophobicContact CG2-CB 4.42Å; V672-V723 HydrophobicContact CG2-CG1 4.36Å; V672-V723 HydrophobicContact CG2-CG2 4.12Å; Y708-V723 HydrophobicContact CD2-CG2 3.82Å; Y708-V723 HydrophobicContact CG-CG2 4.18Å; V709-V723 WeakPolarHBondContact O-CA 3.4Å; V709-V723 VanDerWaalsContact O-CG2 3.31Å; V709-V723 WeakPolarHBondContact O-CG2 3.43Å; T710-V723 HydrophobicContact CG2-CB 3.98Å; T710-V723 HydrophobicContact CG2-CG2 3.72Å; V723-L725 HydrophobicContact CG1-CD2 4.14Å; V723-L725 HydrophobicContact CG2-CD2 3.97Å
724L97.5Very high87.1Confident0 Ų042.4 Ų42.40%020%0.2CC..EExtended strand (participates in β ladder)trans-100.5123.1168-91.759.2000109.1I664 V666 Y708 V709 W855 A856 T859 M860 L863I664-L724 HydrophobicContact CG2-CD2 4.31Å; I664-L724 HydrophobicContact CG2-CG 4.14Å; V666-L724 HydrophobicContact CG1-CD1 4.49Å; V666-L724 HydrophobicContact CG2-CD1 4.02Å; V666-L724 HydrophobicContact CG2-CG 4.31Å; Y708-L724 WeakPolarHBondContact CA-O 3.45Å; Y708-L724 VanDerWaalsContact CB-O 3.24Å; Y708-L724 WeakPolarHBondContact CB-O 3.46Å; V709-L724 PolarHBondContact N-O 3.14Å; V709-L724 VanDerWaalsContact N-O 3.09Å; V709-L724 PolarHBondContact O-N 3.46Å; L724-W855 HydrophobicContact CD1-CE3 4.42Å; L724-W855 HydrophobicContact CD1-CH2 3.56Å; L724-W855 HydrophobicContact CD1-CZ3 3.42Å; L724-W855 VanDerWaalsContact CD1-CZ3 3.42Å; L724-A856 HydrophobicContact CD1-CB 4.42Å; L724-A856 HydrophobicContact CD2-CB 4.13Å; L724-A856 WeakPolarHBondContact CD2-O 3.14Å; L724-T859 HydrophobicContact CB-CG2 4.13Å; L724-T859 HydrophobicContact CD2-CG2 3.9Å; L724-M860 HydrophobicContact CD2-CG 3.76Å; L724-L863 HydrophobicContact CB-CD1 3.7Å
725L97.6Very high87.2Confident1 Ų148.1 Ų48.11%0.00522%0.224CC..EExtended strand (participates in β ladder)trans-99.7127.2172.9-47.8-178.9000108.7I638 V665 T667 V672 I686 V705 Y708 V723I638-L725 HydrophobicContact CD1-CD1 4.07Å; V665-L725 HydrophobicContact CB-CB 4.35Å; V665-L725 HydrophobicContact CG1-CD1 4.48Å; V665-L725 PolarHBondContact N-O 3.32Å; V665-L725 PolarHBondContact O-N 2.8Å; T667-L725 HydrophobicContact CG2-CD1 3.94Å; T667-L725 HydrophobicContact CG2-CG 4.16Å; V672-L725 HydrophobicContact CG1-CD2 4.05Å; I686-L725 HydrophobicContact CD1-CD1 3.91Å; V705-L725 HydrophobicContact CG1-CB 4.23Å; V705-L725 HydrophobicContact CG2-CD1 4.34Å; Y708-L725 VanDerWaalsContact CB-CD2 3.44Å; Y708-L725 HydrophobicContact CD1-CD2 4.24Å; Y708-L725 HydrophobicContact CG-CD2 3.98Å; V723-L725 HydrophobicContact CG1-CD2 4.14Å; V723-L725 HydrophobicContact CG2-CD2 3.97Å
726R96.2Very high87.9Confident25 Ų2547.8 Ų47.89%0.09422%0.22CC..EExtended strand (participates in β ladder)trans-95.5123.9168.7-171.2172.1-178.983.610.3109.6D663 I664 R706 N707 L863D663-R726 CarbonylContact O-C 3.57Å; D663-R726 WeakPolarHBondContact O-CA 3.43Å; D663-R726 IonicContact OD1-NH1 2.69Å; D663-R726 IonicContact OD2-CZ 3.96Å; D663-R726 IonicContact OD2-NE 2.59Å; D663-R726 IonicContact OD2-NH1 2.72Å; D663-R726 PolarHBondContact OD2-NH1 2.84Å; D663-R726 IonicContact OD2-NH2 2.8Å; D663-R726 PolarHBondContact OD2-NH2 3.21Å; I664-R726 HydrophobicContact CD1-CB 4.04Å; I664-R726 HydrophobicContact CD1-CG 3.99Å; R706-R726 WeakPolarHBondContact CB-O 3.42Å; R706-R726 PolarHBondContact N-O 2.87Å; N707-R726 PolarHBondContact O-N 2.95Å; N707-R726 WeakPolarHBondContact OD1-CB 3.43Å; R726-L863 HydrophobicContact CB-CB 4.09Å; R726-L863 HydrophobicContact CB-CD1 4.35Å; R726-L863 VanDerWaalsContact CD-O 3.25Å; R726-L863 WeakPolarHBondContact CD-O 3.3Å
727L95.5Very high88.8Confident2 Ų240.8 Ų40.81%0.0119%0.188CC..EExtended strand (participates in β ladder)trans-72.3147.6176.5-54.2-177.8000110.2D663 V665 I686 L688 R703 L729 V731D663-L727 HydrophobicContact CB-CB 4.43Å; D663-L727 PolarHBondContact O-N 3.38Å; V665-L727 HydrophobicContact CG2-CD1 4.16Å; V665-L727 HydrophobicContact CG2-CD2 4.09Å; V665-L727 HydrophobicContact CG2-CG 4.29Å; I686-L727 HydrophobicContact CB-CD2 4.03Å; I686-L727 HydrophobicContact CG1-CD2 3.79Å; I686-L727 HydrophobicContact CG2-CD2 3.99Å; L688-L727 HydrophobicContact CD1-CD1 4.48Å; R703-L727 HydrophobicContact CB-CB 4.34Å; R703-L727 HydrophobicContact CB-CD1 4.17Å; R703-L727 HydrophobicContact CB-CD2 4.13Å; R703-L727 HydrophobicContact CB-CG 4.44Å; R703-L727 HydrophobicContact CG-CD1 4.17Å; L727-L729 VanDerWaalsContact C-N 3.34Å; L727-L729 PolarHBondContact O-N 3.42Å; L727-V731 HydrophobicContact CD1-CG2 3.84Å
728K91.9Very high89.7Confident77 Ų7737.7 Ų37.734%0.33518%0.175SC..EExtended strand (participates in β ladder)trans-65.1-37.5177.6-174.8174.1-177.7172.60113.3D704 R706D704-K728 HydrophobicContact CB-CB 4.24Å; D704-K728 HydrophobicContact CB-CD 4.27Å; D704-K728 PolarHBondContact O-N 2.81Å; R706-K728 HydrophobicContact CB-CB 4.49Å
729L91.2Very high90.7Very high109 Ų10934.3 Ų34.357%0.57116%0.159SC*.EExtended strand (participates in β ladder)trans-126.2135175.2-67.2174.8000109.1R703 L727R703-L729 WeakPolarHBondContact CD-O 3.29Å; R703-L729 PolarHBondContact NE-O 3.31Å; L727-L729 VanDerWaalsContact C-N 3.34Å; L727-L729 PolarHBondContact O-N 3.42Å
730P89.8Confident91.3Very high45 Ų4534.1 Ų34.129%0.29216%0.158SC..EExtended strand (participates in β ladder)trans-57.8158.6172.9-22.532.3000113L658 Q661 D663L658-P730 HydrophobicContact CD1-CB 4.29Å; L658-P730 HydrophobicContact CD1-CG 4.15Å; Q661-P730 HydrophobicContact CB-CB 4.35Å; Q661-P730 HydrophobicContact CG-CB 4.15Å; D663-P730 HydrophobicContact CB-CB 4.18Å; D663-P730 HydrophobicContact CB-CG 4.16Å
731V87.8Confident91.4Very high0 Ų033.8 Ų33.80%016%0.157CC..EExtended strand (participates in β ladder)trans-115.4121.7178.3178.10000108.6Q661 S662 L688 I701 R703 L727 I737Q661-V731 CarbonylContact C-O 3.55Å; Q661-V731 WeakPolarHBondContact CA-O 3.23Å; Q661-V731 VanDerWaalsContact CB-O 3.26Å; Q661-V731 WeakPolarHBondContact CB-O 3.35Å; S662-V731 PolarHBondContact N-O 3.23Å; S662-V731 PolarHBondContact O-N 3.49Å; L688-V731 HydrophobicContact CD1-CG2 4.12Å; L688-V731 HydrophobicContact CD2-CG1 4.48Å; L688-V731 HydrophobicContact CD2-CG2 4.32Å; I701-V731 HydrophobicContact CD1-CB 4.2Å; I701-V731 HydrophobicContact CD1-CG1 3.42Å; I701-V731 VanDerWaalsContact CD1-CG1 3.42Å; I701-V731 HydrophobicContact CD1-CG2 3.81Å; R703-V731 HydrophobicContact CG-CG2 3.79Å; L727-V731 HydrophobicContact CD1-CG2 3.84Å; V731-I737 HydrophobicContact CG1-CB 4.36Å; V731-I737 HydrophobicContact CG1-CD1 3.9Å; V731-I737 HydrophobicContact CG1-CG2 3.58Å
732R86.1Confident91.2Very high186 Ų18634.9 Ų34.970%0.70216%0.163SC*.EExtended strand (participates in β ladder)trans-71.5143.7178-67.6-178.3178.3170.4-0.9110.9Q661 T734Q661-R732 HydrophobicContact CB-CG 4.46Å; R732-T734 PolarHBondContact O-N 2.8Å
733Y84Confident90.8Very high10 Ų1034.9 Ų34.94%0.03916%0.163CC..  trans-72.5127175.5-55.7-23.4000110.6V599 R600 L653 D655 N660 Q661 S662 I737 P739V599-Y733 HydrophobicContact CG1-CD2 4.32Å; V599-Y733 HydrophobicContact CG1-CE2 3.84Å; R600-Y733 HydrophobicContact CB-CD2 4.44Å; L653-Y733 HydrophobicContact CD2-CE1 4.4Å; D655-Y733 PolarHBondContact OD1-OH 3.5Å; N660-Y733 VanDerWaalsContact C-CD2 3.46Å; N660-Y733 PolarHBondContact O-N 2.97Å; Q661-Y733 VanDerWaalsContact C-CZ 3.42Å; Q661-Y733 PolarHBondContact O-OH 2.8Å; Q661-Y733 VanDerWaalsContact O-OH 3.08Å; S662-Y733 WeakPolarHBondContact CB-OH 2.88Å; Y733-I737 CarbonylContact C-O 3.56Å; Y733-I737 VanDerWaalsContact CA-O 3.24Å; Y733-I737 WeakPolarHBondContact CA-O 3.49Å; Y733-P739 VanDerWaalsContact CE1-CD 3.46Å; Y733-P739 HydrophobicContact CE1-CG 3.97Å; Y733-P739 HydrophobicContact CE2-CG 4.2Å
734T82.6Confident89.9Confident51 Ų5136.6 Ų36.631%0.31317%0.173SC..  trans-125.7-172.1175.975.10000109.8R600 R732 E736 I737R600-T734 VanDerWaalsContact NH1-C 3.33Å; R600-T734 PolarHBondContact NH1-O 3.22Å; R732-T734 PolarHBondContact O-N 2.8Å; T734-E736 WeakPolarHBondContact CB-OE2 3.38Å; T734-E736 PolarHBondContact O-N 2.77Å; T734-E736 PolarHBondContact OG1-N 3.11Å; T734-E736 VanDerWaalsContact OG1-N 3.13Å; T734-E736 PolarHBondContact OG1-OE2 2.82Å; T734-I737 PolarHBondContact N-O 2.55Å; T734-I737 PolarHBondContact OG1-N 2.77Å; T734-I737 VanDerWaalsContact OG1-N 3.1Å
735K80.6Confident88.7Confident132 Ų13242.2 Ų42.257%0.57420%0.198SC*.SBendtrans-69.1-24.9173.3-66.5178.2-178.8177.30111.3A606A606-K735 HydrophobicContact CB-CB 3.89Å; A606-K735 HydrophobicContact CB-CG 4.02Å
736E90.9Very high87Confident55 Ų5549.8 Ų49.826%0.25723%0.233SC..SBendtrans-101.1-16.8-174.1-52.676.8-163.200113.4N630 P633 T734N630-E736 HydrophobicContact CB-CB 4.02Å; N630-E736 HydrophobicContact CB-CG 3.84Å; P633-E736 WeakPolarHBondContact CA-O 3.48Å; P633-E736 VanDerWaalsContact CB-O 3.28Å; P633-E736 WeakPolarHBondContact CB-O 3.26Å; T734-E736 WeakPolarHBondContact CB-OE2 3.38Å; T734-E736 PolarHBondContact O-N 2.77Å; T734-E736 PolarHBondContact OG1-N 3.11Å; T734-E736 VanDerWaalsContact OG1-N 3.13Å; T734-E736 PolarHBondContact OG1-OE2 2.82Å
737I93Very high85.4Confident5 Ų549.9 Ų49.93%0.02624%0.236CC..  trans-131.9118.2178.1-52.3172.8000110.3P633 L653 L688 I701 V731 Y733 T734P633-I737 WeakPolarHBondContact O-CA 3.36Å; L653-I737 HydrophobicContact CD2-CG2 3.83Å; L688-I737 HydrophobicContact CB-CD1 4.01Å; L688-I737 HydrophobicContact CB-CG1 4.36Å; L688-I737 HydrophobicContact CB-CG2 4.46Å; L688-I737 HydrophobicContact CD2-CG2 4.31Å; I701-I737 HydrophobicContact CD1-CD1 3.59Å; I701-I737 HydrophobicContact CG1-CD1 3.76Å; V731-I737 HydrophobicContact CG1-CB 4.36Å; V731-I737 HydrophobicContact CG1-CD1 3.9Å; V731-I737 HydrophobicContact CG1-CG2 3.58Å; Y733-I737 CarbonylContact C-O 3.56Å; Y733-I737 VanDerWaalsContact CA-O 3.24Å; Y733-I737 WeakPolarHBondContact CA-O 3.49Å; T734-I737 PolarHBondContact N-O 2.55Å; T734-I737 PolarHBondContact OG1-N 2.77Å; T734-I737 VanDerWaalsContact OG1-N 3.1Å
738S92.3Very high83.9Confident6 Ų651.4 Ų51.44%0.04225%0.245CC..  trans-164.3152.4174.354.10000109.7P633 W634P633-S738 CarbonylContact C-O 3.55Å; P633-S738 VanDerWaalsContact C-O 3.31Å; P633-S738 WeakPolarHBondContact CB-OG 3.47Å; P633-S738 WeakPolarHBondContact CG-OG 3.48Å; P633-S738 PolarHBondContact O-N 3.34Å; W634-S738 WeakPolarHBondContact CA-O 3.27Å; W634-S738 WeakPolarHBondContact CB-O 3.42Å; W634-S738 PolarHBondContact N-O 2.91Å
739P95Very high82.3Confident2 Ų254.2 Ų54.21%0.01326%0.264CS..PPolyproline II helixtrans-79.2154.2-168.732.5-36.3000112.3C602 G603 L653 I654 D655 Y733C602-P739 HydrophobicContact CB-CB 4.47Å; C602-P739 HydrophobicContact CB-CG 4.03Å; G603-P739 PolarHBondContact N-O 2.94Å; L653-P739 HydrophobicContact CG-CB 4.4Å; L653-P739 VanDerWaalsContact O-CA 3.27Å; L653-P739 WeakPolarHBondContact O-CA 3.06Å; I654-P739 VanDerWaalsContact C-CB 3.4Å; D655-P739 HydrophobicContact CB-CB 4.36Å; D655-P739 HydrophobicContact CB-CG 4.17Å; Y733-P739 VanDerWaalsContact CE1-CD 3.46Å; Y733-P739 HydrophobicContact CE1-CG 3.97Å; Y733-P739 HydrophobicContact CE2-CG 4.2Å
740V95.4Very high80.4Confident0 Ų051.7 Ų51.70%025%0.253CS..BIsolated β-bridgetrans-85.8152.1162.668.50000109.2W634 F652 L653 I654 F816 Y823 A825W634-V740 HydrophobicContact CB-CB 3.89Å; W634-V740 HydrophobicContact CB-CG1 4.22Å; W634-V740 HydrophobicContact CD2-CB 3.74Å; W634-V740 HydrophobicContact CD2-CG2 4.2Å; W634-V740 HydrophobicContact CE3-CB 4.1Å; W634-V740 HydrophobicContact CG-CB 3.64Å; W634-V740 HydrophobicContact CG-CG1 4.22Å; W634-V740 HydrophobicContact CG-CG2 4.45Å; F652-V740 HydrophobicContact CB-CG1 4.38Å; F652-V740 HydrophobicContact CD2-CG1 3.51Å; F652-V740 HydrophobicContact CE2-CG1 4.18Å; F652-V740 HydrophobicContact CG-CG1 4.3Å; L653-V740 PolarHBondContact O-N 3.09Å; I654-V740 HydrophobicContact CG2-CG1 4.39Å; V740-F816 HydrophobicContact CG2-CB 4.43Å; V740-Y823 VanDerWaalsContact CG2-O 3.24Å; V740-Y823 WeakPolarHBondContact CG2-O 3.23Å; V740-A825 HydrophobicContact CG1-CB 3.74Å; V740-A825 HydrophobicContact CG2-CB 4.23Å
741C88.9Confident78.8Confident3 Ų356.8 Ų56.82%0.0228%0.278CS..EExtended strand (participates in β ladder)trans-73.7147175.7-66.10000112.3C602 R822 Y823 F824 A825C602-C741 HydrophobicContact CB-CB 4.05Å; C602-C741 WeakPolarHBondContact CB-SG 3.42Å; C602-C741 PolarHBondContact O-SG 2.71Å; C602-C741 WeakPolarHBondContact SG-CA 3.43Å; C602-C741 WeakPolarHBondContact SG-CB 3.48Å; C602-C741 CovalentContact SG-SG 2.05Å; C602-C741 PolarHBondContact SG-SG 3.33Å; C741-R822 PolarHBondContact SG-NH2 3.4Å; C741-Y823 PolarHBondContact N-O 2.71Å; C741-Y823 VanDerWaalsContact N-O 3.14Å; C741-F824 HydrophobicContact CB-CB 4.46Å; C741-F824 HydrophobicContact CB-CD1 3.27Å; C741-F824 HydrophobicContact CB-CD2 4.49Å; C741-F824 HydrophobicContact CB-CE1 3.45Å; C741-F824 VanDerWaalsContact CB-CE1 3.45Å; C741-F824 HydrophobicContact CB-CG 3.84Å; C741-F824 HydrophobicContact CB-CZ 4.17Å; C741-F824 CarbonylContact O-C 3.54Å; C741-F824 WeakPolarHBondContact O-CA 3.36Å; C741-A825 PolarHBondContact O-N 3.03Å
742L88.4Confident78.1Confident24 Ų2458.2 Ų58.213%0.12629%0.285CS..EExtended strand (participates in β ladder)trans-78.3132.4168.8-152.964.5000109.6I654 M849 A856I654-L742 HydrophobicContact CG2-CD1 4.25Å; L742-M849 HydrophobicContact CD1-CE 3.48Å; L742-M849 VanDerWaalsContact CD1-CE 3.48Å; L742-M849 HydrophobicContact CD1-CG 3.58Å; L742-M849 HydrophobicContact CD1-SD 3.72Å; L742-M849 HydrophobicContact CD2-CE 3.98Å; L742-M849 HydrophobicContact CG-CE 3.96Å; L742-M849 HydrophobicContact CG-CG 4.09Å; L742-A856 HydrophobicContact CD2-CB 3.94Å
743A85.6Confident77.7Confident0 Ų054.8 Ų54.80%028%0.281CS..PPolyproline II helixtrans-70.5142.9174.300000111.4V748 A825 V826 D850A743-V748 HydrophobicContact CB-CG2 3.95Å; A743-A825 VanDerWaalsContact CB-O 3.24Å; A743-A825 WeakPolarHBondContact CB-O 3.43Å; A743-A825 PolarHBondContact N-O 3.42Å; A743-V826 HydrophobicContact CB-CB 4.36Å; A743-V826 HydrophobicContact CB-CG1 3.97Å; A743-D850 HydrophobicContact CB-CB 4.48Å
744T77.6Confident77.9Confident35 Ų3557 Ų5722%0.21530%0.295CS..  trans-116.3165168.375.30000110.2H746 T747 V748T744-H746 PolarHBondContact O-N 3.21Å; T744-H746 VanDerWaalsContact O-N 3.14Å; T744-H746 PolarHBondContact OG1-N 2.68Å; T744-T747 PolarHBondContact N-OG1 3.08Å; T744-T747 PolarHBondContact O-N 3.17Å; T744-T747 PolarHBondContact O-OG1 3.15Å; T744-T747 PolarHBondContact OG1-N 3.1Å; T744-V748 PolarHBondContact O-N 2.8Å; T744-V748 VanDerWaalsContact O-N 3.14Å
745K71.8Confident78.4Confident119 Ų11954.5 Ų54.552%0.51728%0.28SS..Hα-helixtrans-54.3-33.5174.9-66.5-179.5-179.7170.60112.8N749 N851K745-N749 VanDerWaalsContact O-CG 3.31Å; K745-N749 PolarHBondContact O-N 2.54Å; K745-N749 PolarHBondContact O-OD1 2.83Å; K745-N851 WeakPolarHBondContact CE-OD1 3.4Å
746H61.6Low79.1Confident160 Ų16049 Ų4974%0.74126%0.256SS*.Hα-helixtrans-69-39.5177-64.4-71.1000112.6T744T744-H746 PolarHBondContact O-N 3.21Å; T744-H746 VanDerWaalsContact O-N 3.14Å; T744-H746 PolarHBondContact OG1-N 2.68Å
747T63.7Low79.2Confident26 Ų2646.5 Ų46.516%0.1625%0.245CC..Hα-helixtrans-69.9-36.1179.259.40000112.5T744 T750 F824T744-T747 PolarHBondContact N-OG1 3.08Å; T744-T747 PolarHBondContact O-N 3.17Å; T744-T747 PolarHBondContact O-OG1 3.15Å; T744-T747 PolarHBondContact OG1-N 3.1Å; T747-T750 PolarHBondContact O-OG1 2.9Å; T747-F824 HydrophobicContact CG2-CD1 4.1Å; T747-F824 HydrophobicContact CG2-CE1 3.73Å; T747-F824 HydrophobicContact CG2-CZ 4.12Å
748V64.8Low79.2Confident34 Ų3446.5 Ų46.521%0.20625%0.246CC..Hα-helixtrans-79.9-15.1-177177.80000113A743 T744 T750 L752 V826 D850A743-V748 HydrophobicContact CB-CG2 3.95Å; T744-V748 PolarHBondContact O-N 2.8Å; T744-V748 VanDerWaalsContact O-N 3.14Å; V748-T750 PolarHBondContact O-N 2.79Å; V748-T750 VanDerWaalsContact O-N 3.07Å; V748-L752 HydrophobicContact CB-CD1 4.35Å; V748-L752 HydrophobicContact CG1-CD1 4.16Å; V748-L752 HydrophobicContact CG2-CD1 4.24Å; V748-V826 HydrophobicContact CG2-CG1 4.36Å; V748-D850 HydrophobicContact CB-CB 4.41Å; V748-D850 HydrophobicContact CG2-CB 3.79Å
749N57.6Low79.2Confident136 Ų13646.4 Ų46.473%0.72725%0.246SC*.THydrogen-bonded Turntrans-66.3-4.2172.1-80.6-11.4000114K745K745-N749 VanDerWaalsContact O-CG 3.31Å; K745-N749 PolarHBondContact O-N 2.54Å; K745-N749 PolarHBondContact O-OD1 2.83Å
750T50.4Low79Confident56 Ų5646.7 Ų46.734%0.34425%0.247SC..SBendtrans-75.4143.2166.258.70000109.2T747 V748 L752 I819T747-T750 PolarHBondContact O-OG1 2.9Å; V748-T750 PolarHBondContact O-N 2.79Å; V748-T750 VanDerWaalsContact O-N 3.07Å; T750-L752 VanDerWaalsContact C-N 3.3Å; T750-L752 WeakPolarHBondContact O-CG 3.32Å; T750-L752 PolarHBondContact O-N 3.44Å; T750-I819 HydrophobicContact CG2-CG2 4.23Å
751N57.4Low78.5Confident152 Ų15247 Ų4781%0.81325%0.25SC*.  trans-64.588.2178.5-73.4-20.5000110.5D753N751-D753 PolarHBondContact O-N 2.94Å; N751-D753 VanDerWaalsContact O-N 3.13Å
752L71.9Confident78Confident30 Ų3048.1 Ų48.116%0.15726%0.26CS..  trans-84.278.6-179.3-67.4179.2000110.6V748 T750 I779 C817 I819 V826V748-L752 HydrophobicContact CB-CD1 4.35Å; V748-L752 HydrophobicContact CG1-CD1 4.16Å; V748-L752 HydrophobicContact CG2-CD1 4.24Å; T750-L752 VanDerWaalsContact C-N 3.3Å; T750-L752 WeakPolarHBondContact O-CG 3.32Å; T750-L752 PolarHBondContact O-N 3.44Å; L752-I779 HydrophobicContact CB-CD1 4.16Å; L752-I779 WeakPolarHBondContact O-CB 3.47Å; L752-C817 HydrophobicContact CD2-CB 3.87Å; L752-I819 HydrophobicContact CD1-CD1 4.37Å; L752-I819 HydrophobicContact CD2-CD1 3.96Å; L752-I819 HydrophobicContact CD2-CG1 3.9Å; L752-V826 HydrophobicContact CD1-CG1 3.9Å
753D79.3Confident77.3Confident114 Ų11448.1 Ų48.161%0.6126%0.26SS*.  trans-81.6-31.1-179.7-67.2-21.4000112.7N751 R778 I779N751-D753 PolarHBondContact O-N 2.94Å; N751-D753 VanDerWaalsContact O-N 3.13Å; D753-R778 WeakPolarHBondContact O-CA 3.38Å; D753-I779 PolarHBondContact O-N 3.07Å; D753-I779 VanDerWaalsContact O-N 3.16Å
754T87.4Confident76.3Confident56 Ų5652.5 Ų52.534%0.34428%0.281SS..EExtended strand (participates in β ladder)trans-143.2129.3-173.9-59.60000111.6R776 I777 Y800T754-R776 HydrophobicContact CG2-CB 4.16Å; T754-R776 HydrophobicContact CG2-CG 4.17Å; T754-I777 WeakPolarHBondContact CA-O 3.4Å; T754-Y800 HydrophobicContact CG2-CD2 3.65Å; T754-Y800 HydrophobicContact CG2-CE2 3.94Å; T754-Y800 HydrophobicContact CG2-CG 4.41Å
755C93.4Very high75.4Confident0 Ų054.5 Ų54.50%030%0.301CS..EExtended strand (participates in β ladder)trans-132.8-173-179.9-59.60000110.6R776 I777 L815 C817C755-R776 CarbonylContact O-C 3.58Å; C755-R776 WeakPolarHBondContact O-CA 3.45Å; C755-I777 PolarHBondContact N-O 3.01Å; C755-I777 PolarHBondContact O-N 3.39Å; C755-L815 HydrophobicContact CB-CD1 3.85Å; C755-L815 HydrophobicContact CB-CG 4.05Å; C755-C817 HydrophobicContact CB-CB 3.98Å; C755-C817 WeakPolarHBondContact CB-SG 3.48Å; C755-C817 WeakPolarHBondContact SG-CB 3.09Å; C755-C817 CovalentContact SG-SG 2.02Å; C755-C817 PolarHBondContact SG-SG 3.28Å
756F94.5Very high75Confident16 Ų1652 Ų527%0.0731%0.309CS..EExtended strand (participates in β ladder)trans-120147-177.6-59.4-87.8000111.4K611 T775 R776 F816 Y823K611-F756 HydrophobicContact CB-CZ 4.26Å; K611-F756 HydrophobicContact CG-CZ 4.38Å; F756-T775 VanDerWaalsContact CA-O 3.28Å; F756-T775 WeakPolarHBondContact CA-O 3.42Å; F756-R776 HydrophobicContact CD1-CG 3.78Å; F756-R776 HydrophobicContact CE1-CG 3.51Å; F756-R776 HydrophobicContact CZ-CG 4.27Å; F756-F816 HydrophobicContact CB-CD1 4.43Å; F756-F816 HydrophobicContact CB-CD2 4Å; F756-F816 HydrophobicContact CB-CE1 4Å; F756-F816 HydrophobicContact CB-CE2 3.52Å; F756-F816 HydrophobicContact CB-CG 4.44Å; F756-F816 HydrophobicContact CB-CZ 3.52Å; F756-F816 HydrophobicContact CD2-CE2 4.41Å; F756-F816 HydrophobicContact CG-CE2 4.21Å; F756-F816 PolarHBondContact N-O 3.29Å; F756-F816 WeakPolarHBondContact O-CD1 3.25Å; F756-F816 PolarHBondContact O-N 3.19Å; F756-Y823 HydrophobicContact CD2-CE1 4.3Å; F756-Y823 HydrophobicContact CE2-CE1 4.34Å
757A93.4Very high75.5Confident2 Ų247.6 Ų47.62%0.01730%0.296CS..EExtended strand (participates in β ladder)trans-125.9149168.500000109Q774 T775 I777 P806 Y846A757-Q774 CarbonylContact O-C 3.59Å; A757-Q774 VanDerWaalsContact O-CA 3.23Å; A757-Q774 WeakPolarHBondContact O-CA 3.3Å; A757-T775 PolarHBondContact N-O 3.19Å; A757-T775 PolarHBondContact O-N 2.71Å; A757-I777 HydrophobicContact CB-CG1 3.74Å; A757-P806 HydrophobicContact CB-CG 3.61Å; A757-Y846 WeakPolarHBondContact CB-OH 3.13Å
758A93.5Very high76.1Confident5 Ų549.8 Ų49.84%0.04132%0.317CS..EExtended strand (participates in β ladder)trans-150.5153.2-178.900000111.8L632 M635 L772 K773 Q774 S813 F816L632-A758 HydrophobicContact CD1-CB 3.45Å; L632-A758 VanDerWaalsContact CD1-CB 3.45Å; M635-A758 HydrophobicContact CE-CB 4.19Å; M635-A758 WeakPolarHBondContact CE-O 3.48Å; M635-A758 HydrophobicContact SD-CB 4.19Å; A758-L772 HydrophobicContact CB-CD1 4.33Å; A758-K773 CarbonylContact C-O 3.54Å; A758-K773 WeakPolarHBondContact CA-O 3.5Å; A758-K773 WeakPolarHBondContact CB-O 3.47Å; A758-Q774 HydrophobicContact CB-CB 3.83Å; A758-S813 VanDerWaalsContact O-CB 3.29Å; A758-S813 WeakPolarHBondContact O-CB 3.49Å; A758-F816 HydrophobicContact CB-CE1 4.01Å; A758-F816 HydrophobicContact CB-CZ 4.27Å
759G91.9Very high76.7Confident5 Ų549 Ų495%0.05231%0.313CS..EExtended strand (participates in β ladder)trans171.3-174.6175.800000114.4K773 D810G759-K773 PolarHBondContact N-O 3.05Å; G759-K773 PolarHBondContact O-N 3.36Å; G759-K773 VanDerWaalsContact O-N 3.12Å; G759-D810 VanDerWaalsContact C-OD1 3.24Å; G759-D810 WeakPolarHBondContact CA-OD1 3.47Å
760W91.5Very high77.9Confident8 Ų844 Ų443%0.0329%0.29CS..SBendtrans-11215.1-177.6-63.4-90.2000112.6M635 H637 A690 H691 L693 A768 S769 L772 D810M635-W760 HydrophobicContact CB-CH2 3.68Å; M635-W760 HydrophobicContact CB-CZ3 4.08Å; M635-W760 HydrophobicContact CE-CZ3 4.23Å; H637-W760 HydrophobicContact CB-CE3 4.14Å; H637-W760 HydrophobicContact CB-CH2 4.5Å; H637-W760 HydrophobicContact CB-CZ3 4.03Å; A690-W760 HydrophobicContact CB-CZ2 4.41Å; A690-W760 WeakPolarHBondContact O-CZ2 3.35Å; H691-W760 PolarHBondContact O-NE1 3.01Å; L693-W760 HydrophobicContact CD1-CB 3.81Å; L693-W760 HydrophobicContact CD1-CD2 4.06Å; L693-W760 HydrophobicContact CD1-CG 3.55Å; L693-W760 HydrophobicContact CG-CD2 4.45Å; L693-W760 HydrophobicContact CG-CG 4.13Å; W760-A768 WeakPolarHBondContact O-CB 3.28Å; W760-S769 PolarHBondContact O-N 2.93Å; W760-L772 HydrophobicContact CD2-CD1 3.85Å; W760-L772 HydrophobicContact CE3-CD1 4.01Å; W760-L772 HydrophobicContact CH2-CD1 3.94Å; W760-L772 HydrophobicContact CH2-CD2 4.43Å; W760-L772 HydrophobicContact CZ2-CB 3.93Å; W760-L772 HydrophobicContact CZ2-CD1 3.74Å; W760-L772 HydrophobicContact CZ2-CD2 4.13Å; W760-L772 HydrophobicContact CZ2-CG 4.14Å; W760-L772 HydrophobicContact CZ3-CD1 4.06Å; W760-D810 PolarHBondContact N-OD1 3.21Å; W760-D810 VanDerWaalsContact N-OD1 3.14Å
761G84Confident79.8Confident5 Ų541.9 Ų41.95%0.05228%0.278CS..  trans-63.1179.8-177.900000114.4T763 S769 R808 D810G761-T763 PolarHBondContact O-N 3.18Å; G761-S769 PolarHBondContact O-N 2.77Å; G761-R808 CarbonylContact C-O 3.59Å; G761-R808 WeakPolarHBondContact CA-O 3.26Å; G761-D810 VanDerWaalsContact CA-OD1 3.29Å; G761-D810 WeakPolarHBondContact CA-OD1 3.22Å; G761-D810 PolarHBondContact N-OD1 3.5Å
762A77.3Confident81.4Confident28 Ų2834.8 Ų34.823%0.23124%0.241CC..BIsolated β-bridgetrans-58132.3179.900000111.2C807 R808A762-C807 HydrophobicContact CB-CB 4.43Å; A762-C807 VanDerWaalsContact O-CB 3.28Å; A762-C807 WeakPolarHBondContact O-CB 3.43Å; A762-R808 HydrophobicContact CB-CB 4.32Å; A762-R808 PolarHBondContact N-O 2.76Å
763T75Confident82.3Confident23 Ų2336.4 Ų36.414%0.14125%0.246CC..  trans-97.4179.5177.663.10000111G761 A765 G766 S767 K773G761-T763 PolarHBondContact O-N 3.18Å; T763-A765 PolarHBondContact O-N 2.91Å; T763-A765 PolarHBondContact OG1-N 2.72Å; T763-G766 PolarHBondContact O-N 2.92Å; T763-S767 PolarHBondContact N-O 3.03Å; T763-S767 PolarHBondContact OG1-O 2.82Å; T763-K773 HydrophobicContact CG2-CD 4.28Å
764E65Low83Confident92 Ų9231.2 Ų31.243%0.4322%0.218SC..THydrogen-bonded Turntrans-55.3-20.317165-81.9-169.300113.8G766E764-G766 PolarHBondContact O-N 2.95Å
765A58.8Low83.1Confident77 Ų7728.9 Ų28.964%0.63620%0.204SC*.THydrogen-bonded Turntrans-77.2-2.9173.300000113.5T763 S767T763-A765 PolarHBondContact O-N 2.91Å; T763-A765 PolarHBondContact OG1-N 2.72Å; A765-S767 PolarHBondContact O-N 3.44Å
766G61.7Low83Confident66 Ų6630.9 Ų30.968%0.6821%0.211SC*.SBendtrans76.5-8.8-175.100000114.4T763 E764T763-G766 PolarHBondContact O-N 2.92Å; E764-G766 PolarHBondContact O-N 2.95Å
767S72.7Confident82.9Confident69 Ų6930.1 Ų30.148%0.48321%0.208SC..SBendtrans-104151.9176.956.40000112.2T763 A765T763-S767 PolarHBondContact N-O 3.03Å; T763-S767 PolarHBondContact OG1-O 2.82Å; A765-S767 PolarHBondContact O-N 3.44Å
768A75.7Confident82.8Confident71 Ų7135.4 Ų35.459%0.58723%0.228SC*.BIsolated β-bridgetrans-61.6141.8173.500000111.2W760W760-A768 WeakPolarHBondContact O-CB 3.28Å
769S78.8Confident82.7Confident19 Ų1936.9 Ų36.913%0.13323%0.234CC..PPolyproline II helixtrans-76.2130.8177.2-168.30000110.6W760 G761 A771W760-S769 PolarHBondContact O-N 2.93Å; G761-S769 PolarHBondContact O-N 2.77Å; S769-A771 VanDerWaalsContact CB-O 3.32Å; S769-A771 WeakPolarHBondContact CB-O 3.43Å; S769-A771 PolarHBondContact OG-O 2.9Å
770A83Confident82.6Confident29 Ų2937.6 Ų37.624%0.2424%0.238CC..SBendtrans-66.8-45.6171.400000111D692 L693 N694D692-A770 CarbonylContact C-O 3.47Å; D692-A770 VanDerWaalsContact CA-O 3.3Å; D692-A770 WeakPolarHBondContact CA-O 3.02Å; D692-A770 WeakPolarHBondContact OD1-CB 3.16Å; L693-A770 PolarHBondContact N-O 3.36Å; N694-A770 HydrophobicContact CB-CB 4.09Å; N694-A770 VanDerWaalsContact ND2-CB 3.27Å; N694-A770 WeakPolarHBondContact ND2-CB 3.49Å
771A88.9Confident82.3Confident12 Ų1240.9 Ų40.910%0.09926%0.26CS..BIsolated β-bridgetrans-88.4144177.100000112.1E626 H691 S769 K773E626-A771 HydrophobicContact CG-CB 4.01Å; H691-A771 CarbonylContact O-C 3.54Å; H691-A771 WeakPolarHBondContact O-CA 3.05Å; S769-A771 VanDerWaalsContact CB-O 3.32Å; S769-A771 WeakPolarHBondContact CB-O 3.43Å; S769-A771 PolarHBondContact OG-O 2.9Å; A771-K773 PolarHBondContact O-N 3.23Å
772L91.8Very high82.2Confident4 Ų441.7 Ų41.72%0.02126%0.263CS..  trans-62.5122.7177.2-178.962000110.6A627 L632 M635 H691 A758 W760A627-L772 HydrophobicContact CB-CD2 4.25Å; A627-L772 HydrophobicContact CB-CG 4.18Å; A627-L772 PolarHBondContact N-O 2.92Å; L632-L772 HydrophobicContact CB-CD2 4.07Å; L632-L772 HydrophobicContact CD1-CD2 4.07Å; M635-L772 HydrophobicContact CB-CD2 4.24Å; M635-L772 HydrophobicContact CE-CD1 4.31Å; M635-L772 HydrophobicContact CG-CD1 4.46Å; M635-L772 HydrophobicContact CG-CD2 3.99Å; H691-L772 PolarHBondContact O-N 3.37Å; A758-L772 HydrophobicContact CB-CD1 4.33Å; W760-L772 HydrophobicContact CD2-CD1 3.85Å; W760-L772 HydrophobicContact CE3-CD1 4.01Å; W760-L772 HydrophobicContact CH2-CD1 3.94Å; W760-L772 HydrophobicContact CH2-CD2 4.43Å; W760-L772 HydrophobicContact CZ2-CB 3.93Å; W760-L772 HydrophobicContact CZ2-CD1 3.74Å; W760-L772 HydrophobicContact CZ2-CD2 4.13Å; W760-L772 HydrophobicContact CZ2-CG 4.14Å; W760-L772 HydrophobicContact CZ3-CD1 4.06Å
773K91.7Very high82.3Confident63 Ų6344 Ų4427%0.27428%0.277SS..EExtended strand (participates in β ladder)trans-107.8155.2174-67.8-172.4-180-176.20110.7W625 A758 G759 T763 A771W625-K773 CarbonylContact O-C 3.54Å; W625-K773 WeakPolarHBondContact O-CA 3.25Å; A758-K773 CarbonylContact C-O 3.54Å; A758-K773 WeakPolarHBondContact CA-O 3.5Å; A758-K773 WeakPolarHBondContact CB-O 3.47Å; G759-K773 PolarHBondContact N-O 3.05Å; G759-K773 PolarHBondContact O-N 3.36Å; G759-K773 VanDerWaalsContact O-N 3.12Å; T763-K773 HydrophobicContact CG2-CD 4.28Å; A771-K773 PolarHBondContact O-N 3.23Å
774Q92.6Very high82.6Confident6 Ų648 Ų483%0.02829%0.294CS..EExtended strand (participates in β ladder)trans-139.1160.1176.460.9172.255.700111.7L610 W625 A627 L632 A757 A758L610-Q774 PolarHBondContact O-NE2 3.44Å; W625-Q774 HydrophobicContact CD2-CG 4.32Å; W625-Q774 VanDerWaalsContact CE2-NE2 3.32Å; W625-Q774 HydrophobicContact CG-CG 4.48Å; W625-Q774 HydrophobicContact CZ2-CG 4.19Å; W625-Q774 VanDerWaalsContact CZ2-NE2 3.33Å; W625-Q774 PolarHBondContact N-O 3.03Å; W625-Q774 PolarHBondContact O-N 3.28Å; A627-Q774 HydrophobicContact CB-CG 4.16Å; L632-Q774 HydrophobicContact CD1-CB 4.24Å; A757-Q774 CarbonylContact O-C 3.59Å; A757-Q774 VanDerWaalsContact O-CA 3.23Å; A757-Q774 WeakPolarHBondContact O-CA 3.3Å; A758-Q774 HydrophobicContact CB-CB 3.83Å
775T90.8Very high83.5Confident6 Ų643.8 Ų43.84%0.03728%0.275CS..EExtended strand (participates in β ladder)trans-150.9169.2173.9-166.20000112.4F756 A757 I777 S804F756-T775 VanDerWaalsContact CA-O 3.28Å; F756-T775 WeakPolarHBondContact CA-O 3.42Å; A757-T775 PolarHBondContact N-O 3.19Å; A757-T775 PolarHBondContact O-N 2.71Å; T775-I777 HydrophobicContact CG2-CD1 3.93Å; T775-I777 HydrophobicContact CG2-CG1 4.21Å; T775-S804 WeakPolarHBondContact CB-OG 3.35Å; T775-S804 PolarHBondContact OG1-OG 2.95Å
776R91.1Very high84.2Confident42 Ų4248.6 Ų48.616%0.15828%0.282CS..EExtended strand (participates in β ladder)trans-90.7143.4169.6-81.7174.6179.8153.8-9.3111K611 V612 W625 T754 C755 F756 Y800 Y801K611-R776 PolarHBondContact O-NE 3.21Å; K611-R776 PolarHBondContact O-NH1 2.99Å; K611-R776 PolarHBondContact O-NH2 3.27Å; V612-R776 VanDerWaalsContact CG1-NH1 3.31Å; W625-R776 HydrophobicContact CH2-CG 4.19Å; T754-R776 HydrophobicContact CG2-CB 4.16Å; T754-R776 HydrophobicContact CG2-CG 4.17Å; C755-R776 CarbonylContact O-C 3.58Å; C755-R776 WeakPolarHBondContact O-CA 3.45Å; F756-R776 HydrophobicContact CD1-CG 3.78Å; F756-R776 HydrophobicContact CE1-CG 3.51Å; F756-R776 HydrophobicContact CZ-CG 4.27Å; R776-Y800 HydrophobicContact CB-CD1 3.95Å; R776-Y800 HydrophobicContact CB-CD2 4.42Å; R776-Y800 HydrophobicContact CB-CG 3.76Å; R776-Y800 WeakPolarHBondContact O-CB 3.42Å; R776-Y800 PolarHBondContact O-N 3.34Å; R776-Y801 HydrophobicContact CB-CD2 4.3Å; R776-Y801 HydrophobicContact CB-CE2 3.99Å; R776-Y801 HydrophobicContact CG-CE2 4.35Å; R776-Y801 PolarHBondContact NH1-OH 3.47Å
777I91.5Very high84.6Confident0 Ų049 Ų490%027%0.266CS..EExtended strand (participates in β ladder)trans-132.1138.3-177.8-64.3-61.6000109T754 C755 A757 T775 V797 F805 L815T754-I777 WeakPolarHBondContact CA-O 3.4Å; C755-I777 PolarHBondContact N-O 3.01Å; C755-I777 PolarHBondContact O-N 3.39Å; A757-I777 HydrophobicContact CB-CG1 3.74Å; T775-I777 HydrophobicContact CG2-CD1 3.93Å; T775-I777 HydrophobicContact CG2-CG1 4.21Å; I777-V797 HydrophobicContact CG2-CB 3.41Å; I777-V797 VanDerWaalsContact CG2-CB 3.41Å; I777-V797 HydrophobicContact CG2-CG1 3.72Å; I777-V797 HydrophobicContact CG2-CG2 3.82Å; I777-F805 HydrophobicContact CD1-CD2 3.93Å; I777-F805 HydrophobicContact CD1-CE2 4.1Å; I777-L815 HydrophobicContact CB-CD1 4.03Å; I777-L815 HydrophobicContact CG2-CD1 4Å
778R91.9Very high84.2Confident114 Ų11452.2 Ų52.243%0.4327%0.271SS..EExtended strand (participates in β ladder)trans-93.3129.9175.2-67.2179.6-172.2166.48.5109.5D753 V797 R798 Y800D753-R778 WeakPolarHBondContact O-CA 3.38Å; R778-V797 CarbonylContact O-C 3.58Å; R778-V797 WeakPolarHBondContact O-CA 3.32Å; R778-V797 WeakPolarHBondContact O-CB 3.34Å; R778-R798 PolarHBondContact N-O 3.3Å; R778-R798 PolarHBondContact O-N 3.46Å; R778-Y800 HydrophobicContact CG-CD2 3.66Å; R778-Y800 HydrophobicContact CG-CG 4.3Å; R778-Y800 PolarHBondContact NH2-O 3.3Å
779I91.3Very high83.8Confident35 Ų3556.9 Ų56.918%0.17928%0.28CS..EExtended strand (participates in β ladder)trans-83.3127.9167.7-59.3177.2000106.8L752 D753 L795 V797 L815 V826L752-I779 HydrophobicContact CB-CD1 4.16Å; L752-I779 WeakPolarHBondContact O-CB 3.47Å; D753-I779 PolarHBondContact O-N 3.07Å; D753-I779 VanDerWaalsContact O-N 3.16Å; I779-L795 HydrophobicContact CG2-CD2 4.34Å; I779-V797 HydrophobicContact CG1-CG1 4.25Å; I779-L815 HydrophobicContact CD1-CD2 3.98Å; I779-L815 HydrophobicContact CG1-CD2 4.02Å; I779-V826 HydrophobicContact CD1-CG2 4.43Å
780V89.6Confident83.5Confident21 Ų2157.6 Ų57.613%0.12728%0.28CS..EExtended strand (participates in β ladder)trans-118.5149.1-179.2-62.90000110.6I782 C796 R798V780-I782 PolarHBondContact O-N 3.44Å; V780-C796 HydrophobicContact CG2-CB 3.97Å; V780-C796 PolarHBondContact N-O 3.39Å; V780-R798 HydrophobicContact CG1-CB 4.34Å; V780-R798 HydrophobicContact CG1-CG 4.22Å; V780-R798 HydrophobicContact CG2-CG 4.2Å
781P85.1Confident83.1Confident76 Ų7659.7 Ų59.749%0.49429%0.287SS..  trans-54.6138.2174.5-25.734.1000111.6S783 Q784P781-S783 PolarHBondContact O-N 2.99Å; P781-Q784 WeakPolarHBondContact O-CB 3.23Å; P781-Q784 PolarHBondContact O-N 2.85Å
782I83.1Confident82.6Confident22 Ų2262 Ų6211%0.11331%0.306CS..G310 helixtrans-57.6-23.5-178.3-162.163000113.2V780 Q784 C785 D791 I794 C796V780-I782 PolarHBondContact O-N 3.44Å; I782-Q784 PolarHBondContact O-N 2.77Å; I782-C785 HydrophobicContact CD1-CB 4.4Å; I782-C785 WeakPolarHBondContact O-CB 3Å; I782-C785 PolarHBondContact O-N 3.32Å; I782-D791 HydrophobicContact CB-CB 4.45Å; I782-D791 HydrophobicContact CG1-CB 4.46Å; I782-D791 HydrophobicContact CG2-CB 3.87Å; I782-D791 WeakPolarHBondContact CG2-OD1 3.46Å; I782-I794 HydrophobicContact CD1-CD1 3.72Å; I782-I794 HydrophobicContact CD1-CG1 3.9Å; I782-C796 HydrophobicContact CD1-CB 4.02Å
783S78Confident82.2Confident76 Ų7663.6 Ų63.653%0.53131%0.312SS..G310 helixtrans-60.7-25.1176.560.30000113.4P781 C785 K788P781-S783 PolarHBondContact O-N 2.99Å; S783-C785 PolarHBondContact O-N 2.82Å; S783-K788 WeakPolarHBondContact O-CE 3.16Å
784Q82.5Confident82.1Confident107 Ų10761.2 Ų61.250%0.530%0.302SS..G310 helixtrans-84.65.2176.2-57.3-174.219.600113.1P781 I782 R798P781-Q784 WeakPolarHBondContact O-CB 3.23Å; P781-Q784 PolarHBondContact O-N 2.85Å; I782-Q784 PolarHBondContact O-N 2.77Å; Q784-R798 PolarHBondContact O-NH2 2.73Å
785C82.3Confident82Confident5 Ų561.5 Ų61.53%0.03430%0.304CS..SBendtrans-130164.6-172.7-48.70000111I782 S783 C796 F845I782-C785 HydrophobicContact CD1-CB 4.4Å; I782-C785 WeakPolarHBondContact O-CB 3Å; I782-C785 PolarHBondContact O-N 3.32Å; S783-C785 PolarHBondContact O-N 2.82Å; C785-C796 HydrophobicContact CB-CB 3.85Å; C785-C796 WeakPolarHBondContact CB-SG 3.47Å; C785-C796 WeakPolarHBondContact SG-CB 3.46Å; C785-C796 CovalentContact SG-SG 2Å; C785-C796 PolarHBondContact SG-SG 2.82Å; C785-F845 HydrophobicContact CB-CE1 4.01Å; C785-F845 HydrophobicContact CB-CZ 4.35Å
786F74.9Confident82Confident178 Ų17861.2 Ų61.278%0.78130%0.302SS*.SBendtrans-77.6-28.5-169.8-54-75.3000113.7K788F786-K788 PolarHBondContact O-N 2.73Å
787F69.3Low82Confident75 Ų7559.2 Ų59.233%0.32930%0.295SS..  trans-94.459-176-62.5-59.1000114E789 R790 I794 L831 F845F787-E789 VanDerWaalsContact C-N 3.29Å; F787-E789 PolarHBondContact O-N 2.98Å; F787-R790 PolarHBondContact O-N 3.29Å; F787-I794 HydrophobicContact CB-CD1 3.69Å; F787-L831 HydrophobicContact CE2-CD2 4.37Å; F787-F845 HydrophobicContact CD2-CD1 4.2Å; F787-F845 HydrophobicContact CD2-CD2 4.37Å; F787-F845 AromaticContact CD2-CE1 3.72Å; F787-F845 HydrophobicContact CD2-CE1 3.72Å; F787-F845 AromaticContact CD2-CE2 3.92Å; F787-F845 HydrophobicContact CD2-CE2 3.92Å; F787-F845 HydrophobicContact CD2-CG 4.48Å; F787-F845 AromaticContact CD2-CZ 3.57Å; F787-F845 HydrophobicContact CD2-CZ 3.57Å; F787-F845 HydrophobicContact CE2-CD2 4.36Å; F787-F845 AromaticContact CE2-CE2 3.92Å; F787-F845 HydrophobicContact CE2-CE2 3.92Å; F787-F845 HydrophobicContact CE2-CZ 4Å
788K65.2Low82Confident136 Ų13661.6 Ų61.659%0.59130%0.304SS*.G310 helixtrans-59.7-32.6-175.3-62.6-177-177.6-179.10114.6S783 F786 R790S783-K788 WeakPolarHBondContact O-CE 3.16Å; F786-K788 PolarHBondContact O-N 2.73Å; K788-R790 PolarHBondContact O-N 3.26Å
789E65.6Low81.8Confident169 Ų16957 Ų5779%0.7929%0.287SS*.G310 helixtrans-70.2-9.1-177.3-62.9179.5-175.100114.2F787F787-E789 VanDerWaalsContact C-N 3.29Å; F787-E789 PolarHBondContact O-N 2.98Å
790R73.7Confident81.6Confident33 Ų3359 Ų5913%0.12529%0.294CS..G310 helixtrans-109.918-173.3-54.5-169.5-168.71695.5113.5K717 D719 F787 K788 A792 R793 I794K717-R790 PolarHBondContact O-NH1 2.82Å; K717-R790 PolarHBondContact O-NH2 3.02Å; D719-R790 IonicContact OD2-NE 3.8Å; F787-R790 PolarHBondContact O-N 3.29Å; K788-R790 PolarHBondContact O-N 3.26Å; R790-A792 PolarHBondContact O-N 3.27Å; R790-R793 PolarHBondContact O-N 3.16Å; R790-I794 HydrophobicContact CB-CD1 3.86Å; R790-I794 HydrophobicContact CB-CG1 3.8Å; R790-I794 WeakPolarHBondContact O-CG1 3.13Å; R790-I794 PolarHBondContact O-N 2.69Å; R790-I794 VanDerWaalsContact O-N 3.1Å
791D73.5Confident81.3Confident74 Ų7461.6 Ų61.640%0.39630%0.302SS..THydrogen-bonded Turntrans-48.3-40.2-176.7-170.531.4000112.9I782 R793 R848I782-D791 HydrophobicContact CB-CB 4.45Å; I782-D791 HydrophobicContact CG1-CB 4.46Å; I782-D791 HydrophobicContact CG2-CB 3.87Å; I782-D791 WeakPolarHBondContact CG2-OD1 3.46Å; D791-R793 PolarHBondContact O-N 2.84Å; D791-R848 PolarHBondContact O-NE 2.8Å; D791-R848 PolarHBondContact O-NH1 3.03Å; D791-R848 PolarHBondContact O-NH2 3.23Å; D791-R848 IonicContact OD1-CZ 3.41Å; D791-R848 IonicContact OD1-NH1 3.35Å; D791-R848 IonicContact OD1-NH2 3.81Å; D791-R848 PolarHBondContact OD1-NH2 3.48Å
792A78.7Confident81Confident60 Ų6067.2 Ų67.250%0.49631%0.313SS..THydrogen-bonded Turntrans-70.1-9178.400000115.2R790 N851R790-A792 PolarHBondContact O-N 3.27Å; A792-N851 WeakPolarHBondContact O-CB 3.39Å; A792-N851 PolarHBondContact O-ND2 2.85Å
793R84.9Confident80.7Confident38 Ų3871 Ų7114%0.14333%0.326CS..THydrogen-bonded Turntrans-124-18.4-174.7-66.5-170.7-57.5-76.25.5114.5D719 N720 R790 D791 R848 Y852D719-R793 IonicContact OD1-CZ 2.79Å; D719-R793 IonicContact OD1-NE 3.91Å; D719-R793 PolarHBondContact OD1-NE 3.41Å; D719-R793 IonicContact OD1-NH2 3.91Å; D719-R793 IonicContact OD2-CZ 2.67Å; D719-R793 IonicContact OD2-NE 3.5Å; D719-R793 PolarHBondContact OD2-NE 2.74Å; D719-R793 IonicContact OD2-NH2 3.57Å; D719-R793 PolarHBondContact OD2-NH2 2.82Å; N720-R793 WeakPolarHBondContact OD1-CD 3.47Å; R790-R793 PolarHBondContact O-N 3.16Å; D791-R793 PolarHBondContact O-N 2.84Å; R793-R848 WeakPolarHBondContact O-CB 3.11Å; R793-R848 PolarHBondContact O-N 3.37Å; R793-Y852 HydrophobicContact CB-CE2 4.35Å; R793-Y852 WeakPolarHBondContact CD-OH 3.42Å; R793-Y852 HydrophobicContact CG-CE2 4.45Å
794I88.9Confident80.9Confident12 Ų1267.5 Ų67.56%0.06230%0.301CS..EExtended strand (participates in β ladder)trans-127.2150.9-178.260169.5000112.6I782 F787 R790 F845 Y846 R848I782-I794 HydrophobicContact CD1-CD1 3.72Å; I782-I794 HydrophobicContact CD1-CG1 3.9Å; F787-I794 HydrophobicContact CB-CD1 3.69Å; R790-I794 HydrophobicContact CB-CD1 3.86Å; R790-I794 HydrophobicContact CB-CG1 3.8Å; R790-I794 WeakPolarHBondContact O-CG1 3.13Å; R790-I794 PolarHBondContact O-N 2.69Å; R790-I794 VanDerWaalsContact O-N 3.1Å; I794-F845 HydrophobicContact CD1-CD1 3.79Å; I794-F845 HydrophobicContact CD1-CE1 4.21Å; I794-Y846 CarbonylContact C-O 3.58Å; I794-Y846 WeakPolarHBondContact CA-O 3.22Å; I794-R848 PolarHBondContact O-NE 3.35Å; I794-R848 PolarHBondContact O-NH2 2.98Å
795L90.4Very high81.1Confident12 Ų1263.2 Ų63.26%0.06328%0.281CS..EExtended strand (participates in β ladder)trans-103.9133.6164.4-66.6170.1000108I779 L815 V826 F845 Y846 R848I779-L795 HydrophobicContact CG2-CD2 4.34Å; L795-L815 HydrophobicContact CD1-CD2 4.21Å; L795-V826 HydrophobicContact CD1-CB 4.38Å; L795-V826 HydrophobicContact CD1-CG2 4.12Å; L795-V826 VanDerWaalsContact CD1-O 3.3Å; L795-V826 WeakPolarHBondContact CD1-O 3.06Å; L795-F845 WeakPolarHBondContact O-CA 3.44Å; L795-Y846 PolarHBondContact N-O 3.39Å; L795-Y846 PolarHBondContact O-N 3.46Å; L795-R848 HydrophobicContact CD2-CG 4.15Å; L795-R848 HydrophobicContact CG-CB 4.03Å; L795-R848 HydrophobicContact CG-CG 4.09Å
796C90.6Very high81.3Confident1 Ų163.4 Ų63.41%0.00728%0.282CS..EExtended strand (participates in β ladder)trans-97.1138.1171.6-169.20000110V780 I782 C785 F845V780-C796 HydrophobicContact CG2-CB 3.97Å; V780-C796 PolarHBondContact N-O 3.39Å; I782-C796 HydrophobicContact CD1-CB 4.02Å; C785-C796 HydrophobicContact CB-CB 3.85Å; C785-C796 WeakPolarHBondContact CB-SG 3.47Å; C785-C796 WeakPolarHBondContact SG-CB 3.46Å; C785-C796 CovalentContact SG-SG 2Å; C785-C796 PolarHBondContact SG-SG 2.82Å; C796-F845 HydrophobicContact CB-CE1 4.47Å
797V92.1Very high81.8Confident0 Ų056 Ų560%025%0.253CS..EExtended strand (participates in β ladder)trans-135.7156.1-177.9-58.90000113.1I777 R778 I779 F805 L815 V843 G844 Y846I777-V797 HydrophobicContact CG2-CB 3.41Å; I777-V797 VanDerWaalsContact CG2-CB 3.41Å; I777-V797 HydrophobicContact CG2-CG1 3.72Å; I777-V797 HydrophobicContact CG2-CG2 3.82Å; R778-V797 CarbonylContact O-C 3.58Å; R778-V797 WeakPolarHBondContact O-CA 3.32Å; R778-V797 WeakPolarHBondContact O-CB 3.34Å; I779-V797 HydrophobicContact CG1-CG1 4.25Å; V797-F805 HydrophobicContact CG2-CE2 4.06Å; V797-F805 HydrophobicContact CG2-CZ 3.8Å; V797-L815 HydrophobicContact CG1-CD2 3.89Å; V797-V843 WeakPolarHBondContact O-CA 3.43Å; V797-G844 WeakPolarHBondContact CG2-O 3.32Å; V797-G844 PolarHBondContact N-O 3.35Å; V797-G844 PolarHBondContact O-N 2.9Å; V797-Y846 HydrophobicContact CG1-CD2 4.03Å; V797-Y846 HydrophobicContact CG1-CE2 4.4Å; V797-Y846 HydrophobicContact CG2-CD2 3.78Å; V797-Y846 HydrophobicContact CG2-CE2 3.69Å
798R91Very high82.5Confident49 Ų4961.9 Ų61.919%0.18527%0.272CS..EExtended strand (participates in β ladder)trans-132.4165172.5-69.7-178.4179.8-93.30110.8R778 V780 Q784 D841 V843R778-R798 PolarHBondContact N-O 3.3Å; R778-R798 PolarHBondContact O-N 3.46Å; V780-R798 HydrophobicContact CG1-CB 4.34Å; V780-R798 HydrophobicContact CG1-CG 4.22Å; V780-R798 HydrophobicContact CG2-CG 4.2Å; Q784-R798 PolarHBondContact O-NH2 2.73Å; R798-D841 WeakPolarHBondContact CD-OD1 3.45Å; R798-D841 IonicContact CZ-OD1 3.81Å; R798-D841 IonicContact CZ-OD2 2.94Å; R798-D841 PolarHBondContact NH1-O 2.78Å; R798-D841 IonicContact NH1-OD1 3.43Å; R798-D841 PolarHBondContact NH1-OD1 3.25Å; R798-D841 IonicContact NH1-OD2 3.46Å; R798-D841 PolarHBondContact NH1-OD2 2.97Å; R798-V843 HydrophobicContact CG-CG2 4.32Å; R798-V843 VanDerWaalsContact CZ-CG2 3.5Å
799D86.9Confident83.5Confident17 Ų1756 Ų569%0.09125%0.251CS..EExtended strand (participates in β ladder)trans-63.6135176.564.4-21.7000111.8Y801 R802 R803 S804 F805 P842D799-Y801 WeakPolarHBondContact CB-O 3.28Å; D799-R802 VanDerWaalsContact OD2-C 3.29Å; D799-R802 WeakPolarHBondContact OD2-CA 3.41Å; D799-R803 PolarHBondContact OD2-N 3.18Å; D799-S804 WeakPolarHBondContact CB-O 3.48Å; D799-F805 HydrophobicContact CB-CD2 4.16Å; D799-P842 HydrophobicContact CB-CG 4.09Å
800Y87Confident84.7Confident79 Ų7948.7 Ų48.731%0.3122%0.217SC..SBendtrans-82.7-45.6171.1-177.4-83.5000110.8T754 R776 R778T754-Y800 HydrophobicContact CG2-CD2 3.65Å; T754-Y800 HydrophobicContact CG2-CE2 3.94Å; T754-Y800 HydrophobicContact CG2-CG 4.41Å; R776-Y800 HydrophobicContact CB-CD1 3.95Å; R776-Y800 HydrophobicContact CB-CD2 4.42Å; R776-Y800 HydrophobicContact CB-CG 3.76Å; R776-Y800 WeakPolarHBondContact O-CB 3.42Å; R776-Y800 PolarHBondContact O-N 3.34Å; R778-Y800 HydrophobicContact CG-CD2 3.66Å; R778-Y800 HydrophobicContact CG-CG 4.3Å; R778-Y800 PolarHBondContact NH2-O 3.3Å
801Y83.1Confident85.7Confident75 Ų7548.4 Ų48.429%0.29422%0.22SC..SBendtrans-99.8128.5171-63.4-69.6000107.8W625 R776 D799 R803 S804W625-Y801 HydrophobicContact CH2-CE2 4.18Å; W625-Y801 HydrophobicContact CZ3-CD2 4.11Å; W625-Y801 AromaticContact CZ3-CE2 3.72Å; W625-Y801 HydrophobicContact CZ3-CE2 3.72Å; R776-Y801 HydrophobicContact CB-CD2 4.3Å; R776-Y801 HydrophobicContact CB-CE2 3.99Å; R776-Y801 HydrophobicContact CG-CE2 4.35Å; R776-Y801 PolarHBondContact NH1-OH 3.47Å; D799-Y801 WeakPolarHBondContact CB-O 3.28Å; Y801-R803 PolarHBondContact O-N 2.98Å; Y801-S804 WeakPolarHBondContact O-CB 3.22Å; Y801-S804 PolarHBondContact O-N 3.35Å
802R79.6Confident86.8Confident193 Ų19344.9 Ų44.973%0.72820%0.201SC*.THydrogen-bonded Turntrans-42.8129.6-177.8-174.2177-176169.53.3111F623 D799 S804F623-R802 WeakPolarHBondContact CD1-O 3.13Å; F623-R802 WeakPolarHBondContact CE1-O 3.46Å; D799-R802 VanDerWaalsContact OD2-C 3.29Å; D799-R802 WeakPolarHBondContact OD2-CA 3.41Å; R802-S804 PolarHBondContact O-N 2.75Å; R802-S804 VanDerWaalsContact O-N 3.11Å
803R76.4Confident87.6Confident102 Ų10242 Ų4239%0.38518%0.178SC..THydrogen-bonded Turntrans58.67.3-179.4-61.8167.2171.8-174.8-2.3115.9F623 D799 Y801 F805F623-R803 VanDerWaalsContact CB-O 3.28Å; F623-R803 WeakPolarHBondContact CB-O 3.26Å; F623-R803 VanDerWaalsContact CD1-C 3.5Å; F623-R803 HydrophobicContact CD1-CB 3.47Å; F623-R803 VanDerWaalsContact CD1-CB 3.47Å; F623-R803 HydrophobicContact CD2-CB 3.61Å; F623-R803 HydrophobicContact CE1-CB 3.49Å; F623-R803 VanDerWaalsContact CE1-CB 3.49Å; F623-R803 HydrophobicContact CE1-CG 4.29Å; F623-R803 HydrophobicContact CE2-CB 3.6Å; F623-R803 HydrophobicContact CE2-CG 4.16Å; F623-R803 HydrophobicContact CG-CB 3.6Å; F623-R803 VanDerWaalsContact CG-O 3.26Å; F623-R803 WeakPolarHBondContact CG-O 3.48Å; F623-R803 HydrophobicContact CZ-CB 3.56Å; F623-R803 HydrophobicContact CZ-CG 4.03Å; D799-R803 PolarHBondContact OD2-N 3.18Å; Y801-R803 PolarHBondContact O-N 2.98Å; R803-F805 PolarHBondContact O-N 3.02Å
804S83.2Confident88.2Confident2 Ų240.2 Ų40.21%0.01417%0.171CC..  trans-90.5102.6174.9-169.10000110.6F623 G624 T775 D799 Y801 R802F623-S804 VanDerWaalsContact O-CA 3.27Å; F623-S804 WeakPolarHBondContact O-CA 3.33Å; F623-S804 VanDerWaalsContact O-CB 3.28Å; F623-S804 WeakPolarHBondContact O-CB 3.36Å; F623-S804 PolarHBondContact O-OG 3.13Å; G624-S804 PolarHBondContact N-OG 2.97Å; T775-S804 WeakPolarHBondContact CB-OG 3.35Å; T775-S804 PolarHBondContact OG1-OG 2.95Å; D799-S804 WeakPolarHBondContact CB-O 3.48Å; Y801-S804 WeakPolarHBondContact O-CB 3.22Å; Y801-S804 PolarHBondContact O-N 3.35Å; R802-S804 PolarHBondContact O-N 2.75Å; R802-S804 VanDerWaalsContact O-N 3.11Å
805F85.7Confident88.5Confident17 Ų1739.7 Ų39.78%0.07517%0.168CC..  trans-150.4145.6-172.3-151.7-97.4000111.3I777 V797 D799 R803 P833 P842I777-F805 HydrophobicContact CD1-CD2 3.93Å; I777-F805 HydrophobicContact CD1-CE2 4.1Å; V797-F805 HydrophobicContact CG2-CE2 4.06Å; V797-F805 HydrophobicContact CG2-CZ 3.8Å; D799-F805 HydrophobicContact CB-CD2 4.16Å; R803-F805 PolarHBondContact O-N 3.02Å; F805-P833 HydrophobicContact CD1-CG 3.93Å; F805-P833 VanDerWaalsContact CE1-CD 3.45Å; F805-P833 HydrophobicContact CE1-CG 4.28Å; F805-P842 HydrophobicContact CB-CG 3.95Å; F805-P842 HydrophobicContact CD1-CB 4.42Å; F805-P842 HydrophobicContact CD2-CB 4.31Å; F805-P842 HydrophobicContact CD2-CG 3.86Å; F805-P842 HydrophobicContact CG-CB 4.16Å; F805-P842 HydrophobicContact CG-CG 3.89Å
806P86.4Confident88.7Confident9 Ų939.1 Ų39.16%0.05817%0.165CC..  trans-56.4151.8172.2-26.135.4000112.8A757 D810 L829A757-P806 HydrophobicContact CB-CG 3.61Å; P806-D810 HydrophobicContact CB-CB 4.03Å; P806-L829 HydrophobicContact CB-CD2 3.62Å; P806-L829 HydrophobicContact CG-CD2 4.46Å
807C86Confident88.8Confident24 Ų2439.1 Ų39.116%0.16217%0.165CC..  trans-139-169.3-175.5-152.30000114.4A762 G809 D810 C836A762-C807 HydrophobicContact CB-CB 4.43Å; A762-C807 VanDerWaalsContact O-CB 3.28Å; A762-C807 WeakPolarHBondContact O-CB 3.43Å; C807-G809 PolarHBondContact O-N 2.93Å; C807-D810 PolarHBondContact N-OD2 2.88Å; C807-D810 VanDerWaalsContact O-CB 3.29Å; C807-D810 WeakPolarHBondContact O-CB 3.13Å; C807-D810 PolarHBondContact O-N 2.73Å; C807-C836 WeakPolarHBondContact CA-SG 3.32Å; C807-C836 HydrophobicContact CB-CB 3.58Å; C807-C836 WeakPolarHBondContact CB-SG 3.34Å; C807-C836 WeakPolarHBondContact SG-CB 3.2Å; C807-C836 CovalentContact SG-SG 2.04Å; C807-C836 PolarHBondContact SG-SG 3.01Å
808R83.7Confident88.5Confident197 Ų19742.6 Ų42.674%0.74318%0.182SC*.THydrogen-bonded Turntrans-53.5124.3-179-68.4-172.2-179.8-163.90.1110.5G761 A762G761-R808 CarbonylContact C-O 3.59Å; G761-R808 WeakPolarHBondContact CA-O 3.26Å; A762-R808 HydrophobicContact CB-CB 4.32Å; A762-R808 PolarHBondContact N-O 2.76Å
809G85.7Confident87.7Confident14 Ų1440.9 Ų40.914%0.14418%0.176CC..THydrogen-bonded Turntrans101.1-17.5-174.700000114.3C649 S650 C807 S811C649-G809 CarbonylContact C-O 3.53Å; S650-G809 PolarHBondContact N-O 3.07Å; S650-G809 PolarHBondContact OG-O 2.95Å; C807-G809 PolarHBondContact O-N 2.93Å; G809-S811 VanDerWaalsContact C-N 3.34Å
810D91.9Very high86.7Confident14 Ų1446 Ų468%0.07520%0.203CC..  trans-85.3-7.8173.9-61.3-39.8000112.9G759 W760 G761 P806 C807 G812 S813 L829G759-D810 VanDerWaalsContact C-OD1 3.24Å; G759-D810 WeakPolarHBondContact CA-OD1 3.47Å; W760-D810 PolarHBondContact N-OD1 3.21Å; W760-D810 VanDerWaalsContact N-OD1 3.14Å; G761-D810 VanDerWaalsContact CA-OD1 3.29Å; G761-D810 WeakPolarHBondContact CA-OD1 3.22Å; G761-D810 PolarHBondContact N-OD1 3.5Å; P806-D810 HydrophobicContact CB-CB 4.03Å; C807-D810 PolarHBondContact N-OD2 2.88Å; C807-D810 VanDerWaalsContact O-CB 3.29Å; C807-D810 WeakPolarHBondContact O-CB 3.13Å; C807-D810 PolarHBondContact O-N 2.73Å; D810-G812 PolarHBondContact O-N 3.47Å; D810-S813 WeakPolarHBondContact O-CB 3.3Å; D810-S813 PolarHBondContact O-N 2.91Å; D810-S813 PolarHBondContact O-OG 3.25Å; D810-L829 HydrophobicContact CB-CD2 3.83Å; D810-L829 WeakPolarHBondContact O-CD2 3.27Å
811S93.6Very high85.7Confident28 Ų2843.4 Ų43.420%0.19620%0.2CC..THydrogen-bonded Turntrans-47.5134.1178.3-71.80000111.8S650 H670 G809 S813S650-S811 CarbonylContact C-O 3.53Å; S650-S811 PolarHBondContact N-O 3.12Å; H670-S811 PolarHBondContact CE1-OG 2.93Å; H670-S811 WeakPolarHBondContact NE2-CB 2.9Å; H670-S811 PolarHBondContact NE2-OG 3.12Å; G809-S811 VanDerWaalsContact C-N 3.34Å; S811-S813 VanDerWaalsContact C-N 3.28Å; S811-S813 PolarHBondContact O-N 3.24Å
812G96Very high85.3Confident0 Ų041.9 Ų41.90%019%0.194CC..THydrogen-bonded Turntrans81.9-6.5-175.800000115.7S650 T667 D810 L829S650-G812 CarbonylContact O-C 3.59Å; S650-G812 VanDerWaalsContact O-C 3.29Å; S650-G812 WeakPolarHBondContact O-CA 3.36Å; T667-G812 WeakPolarHBondContact OG1-CA 3.34Å; D810-G812 PolarHBondContact O-N 3.47Å; G812-L829 PolarHBondContact N-O 2.79Å
813S95.8Very high85.7Confident0 Ų033 Ų330%016%0.161CC..  trans-62.2151.4172.658.70000112.2A758 D810 S811 L829A758-S813 VanDerWaalsContact O-CB 3.29Å; A758-S813 WeakPolarHBondContact O-CB 3.49Å; D810-S813 WeakPolarHBondContact O-CB 3.3Å; D810-S813 PolarHBondContact O-N 2.91Å; D810-S813 PolarHBondContact O-OG 3.25Å; S811-S813 VanDerWaalsContact C-N 3.28Å; S811-S813 PolarHBondContact O-N 3.24Å; S813-L829 PolarHBondContact O-N 3.28Å
814P97.1Very high86.4Confident0 Ų029.4 Ų29.40%015%0.148CC..EExtended strand (participates in β ladder)trans-74.4142.7178.328.9-30.9000111.4M635 F652 F816 A825 G827M635-P814 HydrophobicContact SD-CG 3.92Å; F652-P814 HydrophobicContact CB-CB 4.24Å; F652-P814 HydrophobicContact CB-CG 3.79Å; F652-P814 HydrophobicContact CD1-CB 3.52Å; F652-P814 HydrophobicContact CD1-CG 3.81Å; F652-P814 HydrophobicContact CD2-CB 4.3Å; F652-P814 HydrophobicContact CE1-CB 3.82Å; F652-P814 HydrophobicContact CG-CB 3.76Å; F652-P814 HydrophobicContact CG-CG 3.88Å; F652-P814 HydrophobicContact CZ-CB 4.31Å; P814-F816 HydrophobicContact CB-CB 4.47Å; P814-F816 HydrophobicContact CB-CD1 4.25Å; P814-F816 HydrophobicContact CG-CD1 3.92Å; P814-A825 HydrophobicContact CB-CB 4.21Å; P814-G827 CarbonylContact C-O 3.58Å; P814-G827 WeakPolarHBondContact CA-O 3.25Å
815L96.4Very high87Confident0 Ų029.3 Ų29.30%015%0.147CC..EExtended strand (participates in β ladder)trans-84.7113.4148.8-174.866000106.5C755 I777 I779 L795 V797 V826 G827 Y846C755-L815 HydrophobicContact CB-CD1 3.85Å; C755-L815 HydrophobicContact CB-CG 4.05Å; I777-L815 HydrophobicContact CB-CD1 4.03Å; I777-L815 HydrophobicContact CG2-CD1 4Å; I779-L815 HydrophobicContact CD1-CD2 3.98Å; I779-L815 HydrophobicContact CG1-CD2 4.02Å; L795-L815 HydrophobicContact CD1-CD2 4.21Å; V797-L815 HydrophobicContact CG1-CD2 3.89Å; L815-V826 HydrophobicContact CB-CG2 4.11Å; L815-V826 HydrophobicContact CD2-CG2 3.86Å; L815-V826 HydrophobicContact CG-CG2 3.82Å; L815-V826 WeakPolarHBondContact O-CG2 3.4Å; L815-V826 PolarHBondContact O-N 2.94Å; L815-G827 PolarHBondContact N-O 3.37Å; L815-G827 PolarHBondContact O-N 2.88Å; L815-Y846 HydrophobicContact CB-CD1 3.43Å; L815-Y846 VanDerWaalsContact CB-CD1 3.43Å; L815-Y846 HydrophobicContact CB-CD2 4.48Å; L815-Y846 HydrophobicContact CB-CE1 3.49Å; L815-Y846 VanDerWaalsContact CB-CE1 3.49Å; L815-Y846 HydrophobicContact CB-CG 3.97Å; L815-Y846 HydrophobicContact CD1-CE2 4.5Å; L815-Y846 HydrophobicContact CD2-CD2 4.33Å; L815-Y846 HydrophobicContact CD2-CG 4.24Å
816F95.5Very high87.4Confident1 Ų128.5 Ų28.50%0.00414%0.144CC..EExtended strand (participates in β ladder)trans-121.2134.2-175.860.9-82000112L632 W634 V740 F756 A758 P814 Y823 F824L632-F816 HydrophobicContact CD1-CZ 3.97Å; L632-F816 HydrophobicContact CD2-CE2 3.74Å; L632-F816 HydrophobicContact CD2-CZ 3.7Å; L632-F816 HydrophobicContact CG-CZ 4.49Å; W634-F816 AromaticContact CZ2-CD2 3.79Å; W634-F816 HydrophobicContact CZ2-CD2 3.79Å; W634-F816 AromaticContact CZ2-CE2 3.87Å; W634-F816 HydrophobicContact CZ2-CE2 3.87Å; W634-F816 HydrophobicContact CZ2-CG 4.41Å; V740-F816 HydrophobicContact CG2-CB 4.43Å; F756-F816 HydrophobicContact CB-CD1 4.43Å; F756-F816 HydrophobicContact CB-CD2 4Å; F756-F816 HydrophobicContact CB-CE1 4Å; F756-F816 HydrophobicContact CB-CE2 3.52Å; F756-F816 HydrophobicContact CB-CG 4.44Å; F756-F816 HydrophobicContact CB-CZ 3.52Å; F756-F816 HydrophobicContact CD2-CE2 4.41Å; F756-F816 HydrophobicContact CG-CE2 4.21Å; F756-F816 PolarHBondContact N-O 3.29Å; F756-F816 WeakPolarHBondContact O-CD1 3.25Å; F756-F816 PolarHBondContact O-N 3.19Å; A758-F816 HydrophobicContact CB-CE1 4.01Å; A758-F816 HydrophobicContact CB-CZ 4.27Å; P814-F816 HydrophobicContact CB-CB 4.47Å; P814-F816 HydrophobicContact CB-CD1 4.25Å; P814-F816 HydrophobicContact CG-CD1 3.92Å; F816-Y823 AromaticContact CD2-CD1 3.69Å; F816-Y823 HydrophobicContact CD2-CD1 3.69Å; F816-Y823 HydrophobicContact CD2-CE1 4.29Å; F816-Y823 HydrophobicContact CD2-CG 4.36Å; F816-Y823 HydrophobicContact CE2-CD1 4.2Å; F816-Y823 HydrophobicContact CE2-CE1 4.39Å; F816-F824 CarbonylContact C-O 3.6Å; F816-F824 WeakPolarHBondContact CA-O 3.44Å
817C91.1Very high87.8Confident1 Ų128.1 Ų28.11%0.00714%0.141CC..EExtended strand (participates in β ladder)trans-118.3145-176.2-45.90000109.8L752 C755 I819 Y823 F824 V826L752-C817 HydrophobicContact CD2-CB 3.87Å; C755-C817 HydrophobicContact CB-CB 3.98Å; C755-C817 WeakPolarHBondContact CB-SG 3.48Å; C755-C817 WeakPolarHBondContact SG-CB 3.09Å; C755-C817 CovalentContact SG-SG 2.02Å; C755-C817 PolarHBondContact SG-SG 3.28Å; C817-I819 HydrophobicContact CB-CG1 4.39Å; C817-Y823 CarbonylContact O-C 3.59Å; C817-Y823 VanDerWaalsContact O-CA 3.29Å; C817-Y823 WeakPolarHBondContact O-CA 3.38Å; C817-F824 PolarHBondContact N-O 3.09Å; C817-F824 PolarHBondContact O-N 2.86Å; C817-V826 HydrophobicContact CB-CG1 4.29Å; C817-V826 WeakPolarHBondContact SG-CG2 3.49Å
818E85.5Confident88.3Confident73 Ų7327 Ų2734%0.34113%0.133SC..EExtended strand (participates in β ladder)trans-86.3117171.2-171.3-178.1-165.100109.3K611 R822 Y823K611-E818 WeakPolarHBondContact CE-OE1 3.37Å; K611-E818 WeakPolarHBondContact CE-OE2 3.5Å; K611-E818 IonicContact NZ-OE1 3.4Å; K611-E818 PolarHBondContact NZ-OE1 3.07Å; K611-E818 IonicContact NZ-OE2 3.45Å; K611-E818 PolarHBondContact NZ-OE2 2.83Å; E818-R822 CarbonylContact C-O 3.44Å; E818-R822 VanDerWaalsContact CA-O 3.3Å; E818-R822 WeakPolarHBondContact CA-O 3.42Å; E818-Y823 HydrophobicContact CB-CD1 4.01Å; E818-Y823 HydrophobicContact CB-CE1 3.73Å; E818-Y823 HydrophobicContact CG-CE1 4.26Å
819I74.7Confident88.9Confident12 Ų1218 Ų186%0.06210%0.1CC..EExtended strand (participates in β ladder)trans-125.4120178.8-53.1172.3000106.5T750 L752 C817 G821 R822 F824T750-I819 HydrophobicContact CG2-CG2 4.23Å; L752-I819 HydrophobicContact CD1-CD1 4.37Å; L752-I819 HydrophobicContact CD2-CD1 3.96Å; L752-I819 HydrophobicContact CD2-CG1 3.9Å; C817-I819 HydrophobicContact CB-CG1 4.39Å; I819-G821 PolarHBondContact O-N 2.83Å; I819-R822 PolarHBondContact N-O 2.65Å; I819-R822 PolarHBondContact O-N 3Å; I819-R822 VanDerWaalsContact O-O 3.13Å; I819-F824 HydrophobicContact CB-CD2 3.8Å; I819-F824 HydrophobicContact CB-CE2 3.94Å; I819-F824 HydrophobicContact CD1-CB 4.15Å; I819-F824 HydrophobicContact CD1-CD2 3.88Å; I819-F824 HydrophobicContact CD1-CG 4.14Å; I819-F824 HydrophobicContact CG1-CD2 4.08Å
820D65.9Low89.1Confident125 Ų12517.9 Ų17.967%0.66810%0.097SC*.THydrogen-bonded Turntrans50.435.5178.1-57.7-33.6000115.1
821G65.9Low89Confident24 Ų2420 Ų2025%0.24711%0.108CC..THydrogen-bonded Turntrans87.83.4178.300000115.4I819I819-G821 PolarHBondContact O-N 2.83Å
822R75.7Confident88.5Confident43 Ų4320.3 Ų20.316%0.16212%0.116CC..EExtended strand (participates in β ladder)trans-121.1153.1176.4-60.7176.368.1-1784.8111.2T576 C602 V604 C741 E818 I819 F824T576-R822 VanDerWaalsContact CG2-NH1 3.33Å; C602-R822 PolarHBondContact O-NE 3.05Å; C602-R822 PolarHBondContact O-NH2 3.27Å; C602-R822 PolarHBondContact SG-NH2 2.76Å; V604-R822 HydrophobicContact CG2-CG 3.78Å; C741-R822 PolarHBondContact SG-NH2 3.4Å; E818-R822 CarbonylContact C-O 3.44Å; E818-R822 VanDerWaalsContact CA-O 3.3Å; E818-R822 WeakPolarHBondContact CA-O 3.42Å; I819-R822 PolarHBondContact N-O 2.65Å; I819-R822 PolarHBondContact O-N 3Å; I819-R822 VanDerWaalsContact O-O 3.13Å; R822-F824 HydrophobicContact CB-CD2 4.44Å; R822-F824 HydrophobicContact CB-CE2 3.82Å
823Y88.2Confident87.6Confident8 Ų821 Ų213%0.03112%0.12CC..EExtended strand (participates in β ladder)trans-96.3127.8175.9-66.7-86000111.9G603 P605 P609 W634 V740 C741 F756 F816 C817 E818G603-Y823 WeakPolarHBondContact CA-O 3.49Å; G603-Y823 WeakPolarHBondContact O-CD2 3.25Å; G603-Y823 PolarHBondContact O-N 2.97Å; P605-Y823 HydrophobicContact CG-CD2 4.33Å; P605-Y823 HydrophobicContact CG-CE2 4.2Å; P609-Y823 HydrophobicContact CG-CE2 3.97Å; W634-Y823 HydrophobicContact CH2-CD1 4.49Å; W634-Y823 AromaticContact CH2-CD2 3.63Å; W634-Y823 HydrophobicContact CH2-CD2 3.63Å; W634-Y823 HydrophobicContact CH2-CE2 4.42Å; W634-Y823 AromaticContact CH2-CG 3.66Å; W634-Y823 HydrophobicContact CH2-CG 3.66Å; W634-Y823 HydrophobicContact CZ2-CD2 4.45Å; W634-Y823 HydrophobicContact CZ2-CG 4.1Å; W634-Y823 HydrophobicContact CZ3-CD2 4.41Å; V740-Y823 VanDerWaalsContact CG2-O 3.24Å; V740-Y823 WeakPolarHBondContact CG2-O 3.23Å; C741-Y823 PolarHBondContact N-O 2.71Å; C741-Y823 VanDerWaalsContact N-O 3.14Å; F756-Y823 HydrophobicContact CD2-CE1 4.3Å; F756-Y823 HydrophobicContact CE2-CE1 4.34Å; F816-Y823 AromaticContact CD2-CD1 3.69Å; F816-Y823 HydrophobicContact CD2-CD1 3.69Å; F816-Y823 HydrophobicContact CD2-CE1 4.29Å; F816-Y823 HydrophobicContact CD2-CG 4.36Å; F816-Y823 HydrophobicContact CE2-CD1 4.2Å; F816-Y823 HydrophobicContact CE2-CE1 4.39Å; C817-Y823 CarbonylContact O-C 3.59Å; C817-Y823 VanDerWaalsContact O-CA 3.29Å; C817-Y823 WeakPolarHBondContact O-CA 3.38Å; E818-Y823 HydrophobicContact CB-CD1 4.01Å; E818-Y823 HydrophobicContact CB-CE1 3.73Å; E818-Y823 HydrophobicContact CG-CE1 4.26Å
824F90.6Very high86.6Confident25 Ų2524.8 Ų24.811%0.1115%0.151CC..EExtended strand (participates in β ladder)trans-116133.1176.9-68.8-99.1000110.1C741 T747 F816 C817 I819 R822 V826C741-F824 HydrophobicContact CB-CB 4.46Å; C741-F824 HydrophobicContact CB-CD1 3.27Å; C741-F824 HydrophobicContact CB-CD2 4.49Å; C741-F824 HydrophobicContact CB-CE1 3.45Å; C741-F824 VanDerWaalsContact CB-CE1 3.45Å; C741-F824 HydrophobicContact CB-CG 3.84Å; C741-F824 HydrophobicContact CB-CZ 4.17Å; C741-F824 CarbonylContact O-C 3.54Å; C741-F824 WeakPolarHBondContact O-CA 3.36Å; T747-F824 HydrophobicContact CG2-CD1 4.1Å; T747-F824 HydrophobicContact CG2-CE1 3.73Å; T747-F824 HydrophobicContact CG2-CZ 4.12Å; F816-F824 CarbonylContact C-O 3.6Å; F816-F824 WeakPolarHBondContact CA-O 3.44Å; C817-F824 PolarHBondContact N-O 3.09Å; C817-F824 PolarHBondContact O-N 2.86Å; I819-F824 HydrophobicContact CB-CD2 3.8Å; I819-F824 HydrophobicContact CB-CE2 3.94Å; I819-F824 HydrophobicContact CD1-CB 4.15Å; I819-F824 HydrophobicContact CD1-CD2 3.88Å; I819-F824 HydrophobicContact CD1-CG 4.14Å; I819-F824 HydrophobicContact CG1-CD2 4.08Å; R822-F824 HydrophobicContact CB-CD2 4.44Å; R822-F824 HydrophobicContact CB-CE2 3.82Å; F824-V826 HydrophobicContact CB-CG1 4.49Å; F824-V826 PolarHBondContact O-N 3.19Å
825A95.9Very high85.6Confident0 Ų029.6 Ų29.60%018%0.177CC..EExtended strand (participates in β ladder)trans-76.5105.3167.900000108.8F652 V740 C741 A743 P814 M849F652-A825 HydrophobicContact CD2-CB 4.08Å; F652-A825 HydrophobicContact CE2-CB 3.53Å; F652-A825 HydrophobicContact CZ-CB 3.97Å; V740-A825 HydrophobicContact CG1-CB 3.74Å; V740-A825 HydrophobicContact CG2-CB 4.23Å; C741-A825 PolarHBondContact O-N 3.03Å; A743-A825 VanDerWaalsContact CB-O 3.24Å; A743-A825 WeakPolarHBondContact CB-O 3.43Å; A743-A825 PolarHBondContact N-O 3.42Å; P814-A825 HydrophobicContact CB-CB 4.21Å; A825-M849 WeakPolarHBondContact O-CG 3.48Å
826V94.3Very high84.7Confident1 Ų130 Ų301%0.00618%0.18CC..EExtended strand (participates in β ladder)trans-93.6-15.4179.4-57.70000112A743 V748 L752 I779 L795 L815 C817 F824 M849A743-V826 HydrophobicContact CB-CB 4.36Å; A743-V826 HydrophobicContact CB-CG1 3.97Å; V748-V826 HydrophobicContact CG2-CG1 4.36Å; L752-V826 HydrophobicContact CD1-CG1 3.9Å; I779-V826 HydrophobicContact CD1-CG2 4.43Å; L795-V826 HydrophobicContact CD1-CB 4.38Å; L795-V826 HydrophobicContact CD1-CG2 4.12Å; L795-V826 VanDerWaalsContact CD1-O 3.3Å; L795-V826 WeakPolarHBondContact CD1-O 3.06Å; L815-V826 HydrophobicContact CB-CG2 4.11Å; L815-V826 HydrophobicContact CD2-CG2 3.86Å; L815-V826 HydrophobicContact CG-CG2 3.82Å; L815-V826 WeakPolarHBondContact O-CG2 3.4Å; L815-V826 PolarHBondContact O-N 2.94Å; C817-V826 HydrophobicContact CB-CG1 4.29Å; C817-V826 WeakPolarHBondContact SG-CG2 3.49Å; F824-V826 HydrophobicContact CB-CG1 4.49Å; F824-V826 PolarHBondContact O-N 3.19Å; V826-M849 VanDerWaalsContact O-CB 3.3Å; V826-M849 WeakPolarHBondContact O-CB 3.33Å; V826-M849 PolarHBondContact O-N 2.83Å
827G94.9Very high83.5Confident0 Ų032.1 Ų32.10%020%0.195CC..EExtended strand (participates in β ladder)trans-162.1171.8171.800000116.1P814 L815 V847P814-G827 CarbonylContact C-O 3.58Å; P814-G827 WeakPolarHBondContact CA-O 3.25Å; L815-G827 PolarHBondContact N-O 3.37Å; L815-G827 PolarHBondContact O-N 2.88Å; G827-V847 CarbonylContact C-O 3.53Å; G827-V847 WeakPolarHBondContact CA-O 3.46Å
828V96.7Very high82.6Confident0 Ų035.6 Ų35.60%022%0.219CC..EExtended strand (participates in β ladder)trans-118.4125.1-179.4-173.90000109.4F652 V666 A668 I722 S830 Y846 V847 M849F652-V828 HydrophobicContact CE1-CG1 4.48Å; F652-V828 HydrophobicContact CE1-CG2 3.93Å; F652-V828 HydrophobicContact CZ-CG2 3.9Å; V666-V828 HydrophobicContact CG1-CG2 3.84Å; A668-V828 HydrophobicContact CB-CG1 4.47Å; I722-V828 HydrophobicContact CD1-CG2 4Å; I722-V828 HydrophobicContact CG1-CG2 4.33Å; V828-S830 PolarHBondContact O-N 2.81Å; V828-S830 VanDerWaalsContact O-N 3.12Å; V828-Y846 CarbonylContact O-C 3.53Å; V828-Y846 WeakPolarHBondContact O-CA 3.27Å; V828-V847 HydrophobicContact CB-CB 4.14Å; V828-V847 HydrophobicContact CB-CG2 4.4Å; V828-V847 PolarHBondContact N-O 3.08Å; V828-V847 PolarHBondContact O-N 3.16Å; V828-M849 HydrophobicContact CG2-SD 4.34Å
829L94.8Very high82Confident8 Ų836 Ų364%0.04222%0.221CC..EExtended strand (participates in β ladder)trans-63.7115.7-176.8-179.762.2000110.2P806 D810 G812 S813 Y846P806-L829 HydrophobicContact CB-CD2 3.62Å; P806-L829 HydrophobicContact CG-CD2 4.46Å; D810-L829 HydrophobicContact CB-CD2 3.83Å; D810-L829 WeakPolarHBondContact O-CD2 3.27Å; G812-L829 PolarHBondContact N-O 2.79Å; S813-L829 PolarHBondContact O-N 3.28Å; L829-Y846 VanDerWaalsContact CA-CD1 3.44Å; L829-Y846 VanDerWaalsContact CA-CE1 3.47Å; L829-Y846 HydrophobicContact CB-CD1 4.03Å; L829-Y846 HydrophobicContact CB-CE1 3.48Å; L829-Y846 VanDerWaalsContact CB-CE1 3.48Å; L829-Y846 HydrophobicContact CD1-CD2 4.22Å; L829-Y846 HydrophobicContact CD1-CE1 4.06Å; L829-Y846 HydrophobicContact CD1-CE2 3.64Å; L829-Y846 HydrophobicContact CG-CE1 4.33Å
830S91.6Very high82Confident12 Ų1240.6 Ų40.68%0.08425%0.252CS..EExtended strand (participates in β ladder)trans-106.5-56.6-1791740000111.4H670 D721 V828 F845H670-S830 PolarHBondContact CE1-O 2.77Å; D721-S830 VanDerWaalsContact CB-OG 3.3Å; D721-S830 WeakPolarHBondContact CB-OG 3.16Å; D721-S830 WeakPolarHBondContact OD2-CA 3.08Å; D721-S830 VanDerWaalsContact OD2-CB 3.26Å; D721-S830 WeakPolarHBondContact OD2-CB 3.35Å; D721-S830 PolarHBondContact OD2-OG 2.97Å; V828-S830 PolarHBondContact O-N 2.81Å; V828-S830 VanDerWaalsContact O-N 3.12Å; S830-F845 PolarHBondContact N-O 2.85Å
831L87.9Confident82.6Confident58 Ų5838.7 Ų38.730%0.30424%0.241SC..EExtended strand (participates in β ladder)trans-133.5137-174.3-173.668.8000111.3F787 G844 F845F787-L831 HydrophobicContact CE2-CD2 4.37Å; L831-G844 CarbonylContact O-C 3.59Å; L831-G844 WeakPolarHBondContact O-CA 3.38Å; L831-F845 HydrophobicContact CB-CB 4.3Å; L831-F845 HydrophobicContact CB-CD2 4.17Å; L831-F845 HydrophobicContact CD2-CD2 3.95Å; L831-F845 HydrophobicContact CD2-CE2 4.35Å; L831-F845 HydrophobicContact CG-CD2 4.35Å; L831-F845 PolarHBondContact N-O 2.79Å; L831-F845 VanDerWaalsContact N-O 3.16Å; L831-F845 PolarHBondContact O-N 3.09Å
832G83.3Confident83.5Confident35 Ų3537.5 Ų37.536%0.36123%0.23SC..  trans-128.5176.4174.300000112.4
833P78.4Confident84.1Confident15 Ų1536.5 Ų36.510%0.09723%0.228CC..  trans-60.1148.6175.228.7-38.3000111.3F805 N835 C836 E839 P842F805-P833 HydrophobicContact CD1-CG 3.93Å; F805-P833 VanDerWaalsContact CE1-CD 3.45Å; F805-P833 HydrophobicContact CE1-CG 4.28Å; P833-N835 PolarHBondContact O-N 3.24Å; P833-C836 HydrophobicContact CG-CB 4.21Å; P833-E839 WeakPolarHBondContact CB-OE2 3.46Å; P833-P842 HydrophobicContact CB-CB 4.1Å; P833-P842 HydrophobicContact CG-CB 3.75Å
834A73.3Confident84.1Confident79 Ų7936.1 Ų36.165%0.65323%0.226SC*.SBendtrans-60.3-36.217800000112
835N76.6Confident84.2Confident102 Ų10235.7 Ų35.755%0.54523%0.225SC..SBendtrans-126.895.2175.6-71.2-34.9000110.8P833 S837 S838 E839P833-N835 PolarHBondContact O-N 3.24Å; N835-S837 PolarHBondContact O-N 2.87Å; N835-S837 VanDerWaalsContact O-N 3.13Å; N835-S838 WeakPolarHBondContact CB-OG 3.29Å; N835-S838 PolarHBondContact O-N 3.03Å; N835-E839 PolarHBondContact O-N 2.87Å
836C77.7Confident84.1Confident8 Ų835.7 Ų35.75%0.05423%0.225CC..THydrogen-bonded Turntrans-63.7-22-174-30.40000114.6C807 P833C807-C836 WeakPolarHBondContact CA-SG 3.32Å; C807-C836 HydrophobicContact CB-CB 3.58Å; C807-C836 WeakPolarHBondContact CB-SG 3.34Å; C807-C836 WeakPolarHBondContact SG-CB 3.2Å; C807-C836 CovalentContact SG-SG 2.04Å; C807-C836 PolarHBondContact SG-SG 3.01Å; P833-C836 HydrophobicContact CG-CB 4.21Å
837S71.1Confident84Confident46 Ų4635.8 Ų35.832%0.32223%0.225SC..THydrogen-bonded Turntrans-96.6-24.6-176.1-62.70000114.8N835N835-S837 PolarHBondContact O-N 2.87Å; N835-S837 VanDerWaalsContact O-N 3.13Å
838S71.6Confident83.8Confident73 Ų7338 Ų3851%0.5123%0.234SC..THydrogen-bonded Turntrans-108.2-21.7-170.262.80000114.3N835N835-S838 WeakPolarHBondContact CB-OG 3.29Å; N835-S838 PolarHBondContact O-N 3.03Å
839E73.5Confident83.6Confident82 Ų8238 Ų3838%0.38323%0.234SC..SBendtrans-71.5124.6-177.2-164.6163.1174.100110.9P833 N835 D841P833-E839 WeakPolarHBondContact CB-OE2 3.46Å; N835-E839 PolarHBondContact O-N 2.87Å; E839-D841 PolarHBondContact O-N 2.78Å
840P74Confident83.1Confident108 Ų10838.3 Ų38.370%0.70124%0.235SC*.SBendtrans-70.7122.4172.527-29.2000109.5
841D78.1Confident82.8Confident85 Ų8540.3 Ų40.346%0.45525%0.245SC..SBendtrans61.164.8177.7-17210.8000113.1R798 E839R798-D841 WeakPolarHBondContact CD-OD1 3.45Å; R798-D841 IonicContact CZ-OD1 3.81Å; R798-D841 IonicContact CZ-OD2 2.94Å; R798-D841 PolarHBondContact NH1-O 2.78Å; R798-D841 IonicContact NH1-OD1 3.43Å; R798-D841 PolarHBondContact NH1-OD1 3.25Å; R798-D841 IonicContact NH1-OD2 3.46Å; R798-D841 PolarHBondContact NH1-OD2 2.97Å; E839-D841 PolarHBondContact O-N 2.78Å
842P84.5Confident82.8Confident0 Ų037.9 Ų37.90%023%0.232CC..  trans-64.1138.3-176.227.6-35000112D799 F805 P833D799-P842 HydrophobicContact CB-CG 4.09Å; F805-P842 HydrophobicContact CB-CG 3.95Å; F805-P842 HydrophobicContact CD1-CB 4.42Å; F805-P842 HydrophobicContact CD2-CB 4.31Å; F805-P842 HydrophobicContact CD2-CG 3.86Å; F805-P842 HydrophobicContact CG-CB 4.16Å; F805-P842 HydrophobicContact CG-CG 3.89Å; P833-P842 HydrophobicContact CB-CB 4.1Å; P833-P842 HydrophobicContact CG-CB 3.75Å
843V88.2Confident82.9Confident21 Ų2138.2 Ų38.213%0.12722%0.224CC..EExtended strand (participates in β ladder)trans-105.6137.2172.9-1790000109.3V797 R798 F845V797-V843 WeakPolarHBondContact O-CA 3.43Å; R798-V843 HydrophobicContact CG-CG2 4.32Å; R798-V843 VanDerWaalsContact CZ-CG2 3.5Å; V843-F845 HydrophobicContact CG1-CE2 4.22Å; V843-F845 HydrophobicContact CG1-CZ 3.98Å
844G89.5Confident82.9Confident0 Ų042.4 Ų42.40%025%0.246CC..EExtended strand (participates in β ladder)trans-137.7170.1170.900000113.1V797 L831V797-G844 WeakPolarHBondContact CG2-O 3.32Å; V797-G844 PolarHBondContact N-O 3.35Å; V797-G844 PolarHBondContact O-N 2.9Å; L831-G844 CarbonylContact O-C 3.59Å; L831-G844 WeakPolarHBondContact O-CA 3.38Å
845F91.6Very high83.5Confident17 Ų1740 Ų408%0.07522%0.219CC..EExtended strand (participates in β ladder)trans-131.3129.4-172-58.2-81.5000110.7C785 F787 I794 L795 C796 S830 L831 V843C785-F845 HydrophobicContact CB-CE1 4.01Å; C785-F845 HydrophobicContact CB-CZ 4.35Å; F787-F845 HydrophobicContact CD2-CD1 4.2Å; F787-F845 HydrophobicContact CD2-CD2 4.37Å; F787-F845 AromaticContact CD2-CE1 3.72Å; F787-F845 HydrophobicContact CD2-CE1 3.72Å; F787-F845 AromaticContact CD2-CE2 3.92Å; F787-F845 HydrophobicContact CD2-CE2 3.92Å; F787-F845 HydrophobicContact CD2-CG 4.48Å; F787-F845 AromaticContact CD2-CZ 3.57Å; F787-F845 HydrophobicContact CD2-CZ 3.57Å; F787-F845 HydrophobicContact CE2-CD2 4.36Å; F787-F845 AromaticContact CE2-CE2 3.92Å; F787-F845 HydrophobicContact CE2-CE2 3.92Å; F787-F845 HydrophobicContact CE2-CZ 4Å; I794-F845 HydrophobicContact CD1-CD1 3.79Å; I794-F845 HydrophobicContact CD1-CE1 4.21Å; L795-F845 WeakPolarHBondContact O-CA 3.44Å; C796-F845 HydrophobicContact CB-CE1 4.47Å; S830-F845 PolarHBondContact N-O 2.85Å; L831-F845 HydrophobicContact CB-CB 4.3Å; L831-F845 HydrophobicContact CB-CD2 4.17Å; L831-F845 HydrophobicContact CD2-CD2 3.95Å; L831-F845 HydrophobicContact CD2-CE2 4.35Å; L831-F845 HydrophobicContact CG-CD2 4.35Å; L831-F845 PolarHBondContact N-O 2.79Å; L831-F845 VanDerWaalsContact N-O 3.16Å; L831-F845 PolarHBondContact O-N 3.09Å; V843-F845 HydrophobicContact CG1-CE2 4.22Å; V843-F845 HydrophobicContact CG1-CZ 3.98Å
846Y93.6Very high84Confident0 Ų035.1 Ų35.10%019%0.193CC..EExtended strand (participates in β ladder)trans-112.9145.4172.5-76.1-103.6000109.4A757 I794 L795 V797 L815 V828 L829A757-Y846 WeakPolarHBondContact CB-OH 3.13Å; I794-Y846 CarbonylContact C-O 3.58Å; I794-Y846 WeakPolarHBondContact CA-O 3.22Å; L795-Y846 PolarHBondContact N-O 3.39Å; L795-Y846 PolarHBondContact O-N 3.46Å; V797-Y846 HydrophobicContact CG1-CD2 4.03Å; V797-Y846 HydrophobicContact CG1-CE2 4.4Å; V797-Y846 HydrophobicContact CG2-CD2 3.78Å; V797-Y846 HydrophobicContact CG2-CE2 3.69Å; L815-Y846 HydrophobicContact CB-CD1 3.43Å; L815-Y846 VanDerWaalsContact CB-CD1 3.43Å; L815-Y846 HydrophobicContact CB-CD2 4.48Å; L815-Y846 HydrophobicContact CB-CE1 3.49Å; L815-Y846 VanDerWaalsContact CB-CE1 3.49Å; L815-Y846 HydrophobicContact CB-CG 3.97Å; L815-Y846 HydrophobicContact CD1-CE2 4.5Å; L815-Y846 HydrophobicContact CD2-CD2 4.33Å; L815-Y846 HydrophobicContact CD2-CG 4.24Å; V828-Y846 CarbonylContact O-C 3.53Å; V828-Y846 WeakPolarHBondContact O-CA 3.27Å; L829-Y846 VanDerWaalsContact CA-CD1 3.44Å; L829-Y846 VanDerWaalsContact CA-CE1 3.47Å; L829-Y846 HydrophobicContact CB-CD1 4.03Å; L829-Y846 HydrophobicContact CB-CE1 3.48Å; L829-Y846 VanDerWaalsContact CB-CE1 3.48Å; L829-Y846 HydrophobicContact CD1-CD2 4.22Å; L829-Y846 HydrophobicContact CD1-CE1 4.06Å; L829-Y846 HydrophobicContact CD1-CE2 3.64Å; L829-Y846 HydrophobicContact CG-CE1 4.33Å
847V93.3Very high84.2Confident3 Ų338.1 Ų38.12%0.01821%0.208CC..EExtended strand (participates in β ladder)trans-63135.7165.2-178.90000108.5D721 I722 G827 V828 M849 Y852D721-V847 HydrophobicContact CB-CG2 4.21Å; D721-V847 WeakPolarHBondContact O-CG2 3.21Å; I722-V847 HydrophobicContact CB-CG1 4.36Å; I722-V847 HydrophobicContact CD1-CG1 4.46Å; G827-V847 CarbonylContact C-O 3.53Å; G827-V847 WeakPolarHBondContact CA-O 3.46Å; V828-V847 HydrophobicContact CB-CB 4.14Å; V828-V847 HydrophobicContact CB-CG2 4.4Å; V828-V847 PolarHBondContact N-O 3.08Å; V828-V847 PolarHBondContact O-N 3.16Å; V847-M849 PolarHBondContact O-N 3.29Å; V847-Y852 HydrophobicContact CG1-CD2 3.71Å; V847-Y852 HydrophobicContact CG1-CE1 4.33Å; V847-Y852 HydrophobicContact CG1-CE2 3.45Å; V847-Y852 VanDerWaalsContact CG1-CE2 3.45Å; V847-Y852 HydrophobicContact CG1-CG 4.27Å
848R91.5Very high84.5Confident46 Ų4642.4 Ų42.417%0.17422%0.221CC..EExtended strand (participates in β ladder)trans-83.495.9-177.3-178.7172.9-62.3-171.811.1110.9D791 R793 I794 L795 D850 N851 Y852D791-R848 PolarHBondContact O-NE 2.8Å; D791-R848 PolarHBondContact O-NH1 3.03Å; D791-R848 PolarHBondContact O-NH2 3.23Å; D791-R848 IonicContact OD1-CZ 3.41Å; D791-R848 IonicContact OD1-NH1 3.35Å; D791-R848 IonicContact OD1-NH2 3.81Å; D791-R848 PolarHBondContact OD1-NH2 3.48Å; R793-R848 WeakPolarHBondContact O-CB 3.11Å; R793-R848 PolarHBondContact O-N 3.37Å; I794-R848 PolarHBondContact O-NE 3.35Å; I794-R848 PolarHBondContact O-NH2 2.98Å; L795-R848 HydrophobicContact CD2-CG 4.15Å; L795-R848 HydrophobicContact CG-CB 4.03Å; L795-R848 HydrophobicContact CG-CG 4.09Å; R848-D850 WeakPolarHBondContact CG-OD1 3.49Å; R848-D850 PolarHBondContact O-N 2.72Å; R848-N851 PolarHBondContact O-N 2.55Å; R848-Y852 VanDerWaalsContact O-CD2 3.27Å; R848-Y852 WeakPolarHBondContact O-CD2 3.39Å
849M90.7Very high85.1Confident0 Ų039 Ų390%020%0.198CC..G310 helixtrans-63.4-33.1-165-168.467.5-124.900114.5I722 L742 A825 V826 V828 V847 N851 Y852 H853 A856I722-M849 HydrophobicContact CD1-CE 4.05Å; I722-M849 HydrophobicContact CD1-SD 3.82Å; L742-M849 HydrophobicContact CD1-CE 3.48Å; L742-M849 VanDerWaalsContact CD1-CE 3.48Å; L742-M849 HydrophobicContact CD1-CG 3.58Å; L742-M849 HydrophobicContact CD1-SD 3.72Å; L742-M849 HydrophobicContact CD2-CE 3.98Å; L742-M849 HydrophobicContact CG-CE 3.96Å; L742-M849 HydrophobicContact CG-CG 4.09Å; A825-M849 WeakPolarHBondContact O-CG 3.48Å; V826-M849 VanDerWaalsContact O-CB 3.3Å; V826-M849 WeakPolarHBondContact O-CB 3.33Å; V826-M849 PolarHBondContact O-N 2.83Å; V828-M849 HydrophobicContact CG2-SD 4.34Å; V847-M849 PolarHBondContact O-N 3.29Å; M849-N851 PolarHBondContact O-N 2.9Å; M849-Y852 CarbonylContact O-C 3.57Å; M849-Y852 WeakPolarHBondContact O-CA 3.12Å; M849-Y852 PolarHBondContact O-N 2.79Å; M849-H853 PolarHBondContact O-N 2.87Å; M849-A856 HydrophobicContact CE-CB 3.9Å
850D84.8Confident85.6Confident15 Ų1536 Ų368%0.0818%0.184CC..G310 helixtrans-60.9-28.6179.853.8-62.9000113.5A743 V748 R848A743-D850 HydrophobicContact CB-CB 4.48Å; V748-D850 HydrophobicContact CB-CB 4.41Å; V748-D850 HydrophobicContact CG2-CB 3.79Å; R848-D850 WeakPolarHBondContact CG-OD1 3.49Å; R848-D850 PolarHBondContact O-N 2.72Å
851N86.1Confident85.8Confident53 Ų5335.3 Ų35.328%0.28317%0.171SC..G310 helixtrans-85.4-11.6174.6-73.5-30.9000113.6K745 A792 R848 M849K745-N851 WeakPolarHBondContact CE-OD1 3.4Å; A792-N851 WeakPolarHBondContact O-CB 3.39Å; A792-N851 PolarHBondContact O-ND2 2.85Å; R848-N851 PolarHBondContact O-N 2.55Å; M849-N851 PolarHBondContact O-N 2.9Å
852Y87.2Confident85.9Confident7 Ų736.2 Ų36.23%0.02717%0.173CC..THydrogen-bonded Turntrans-104.53.1175.4-70.7-104.7000112.2H711 N720 I722 R793 V847 R848 M849 D854 W855 A856H711-Y852 HydrophobicContact CB-CE1 4.47Å; H711-Y852 AromaticContact CD2-CD1 3.65Å; H711-Y852 AromaticContact CD2-CE1 3.48Å; H711-Y852 VanDerWaalsContact CD2-CE1 3.48Å; H711-Y852 WeakPolarHBondContact CD2-CE1 3.29Å; N720-Y852 HydrophobicContact CB-CE1 4.43Å; N720-Y852 PolarHBondContact OD1-OH 3.37Å; I722-Y852 HydrophobicContact CG2-CD1 3.7Å; I722-Y852 HydrophobicContact CG2-CE1 3.73Å; R793-Y852 HydrophobicContact CB-CE2 4.35Å; R793-Y852 WeakPolarHBondContact CD-OH 3.42Å; R793-Y852 HydrophobicContact CG-CE2 4.45Å; V847-Y852 HydrophobicContact CG1-CD2 3.71Å; V847-Y852 HydrophobicContact CG1-CE1 4.33Å; V847-Y852 HydrophobicContact CG1-CE2 3.45Å; V847-Y852 VanDerWaalsContact CG1-CE2 3.45Å; V847-Y852 HydrophobicContact CG1-CG 4.27Å; R848-Y852 VanDerWaalsContact O-CD2 3.27Å; R848-Y852 WeakPolarHBondContact O-CD2 3.39Å; M849-Y852 CarbonylContact O-C 3.57Å; M849-Y852 WeakPolarHBondContact O-CA 3.12Å; M849-Y852 PolarHBondContact O-N 2.79Å; Y852-D854 PolarHBondContact O-N 3.15Å; Y852-W855 HydrophobicContact CD1-CE3 4.09Å; Y852-W855 PolarHBondContact O-N 3.47Å; Y852-A856 WeakPolarHBondContact O-CB 3.43Å; Y852-A856 PolarHBondContact O-N 3.49Å
853H85Confident85.8Confident42 Ų4236.3 Ų36.319%0.19417%0.173CC..Hα-helixtrans-53.4-56.2-179.3178.2-86.7000111.9M849 W855 A856 I857M849-H853 PolarHBondContact O-N 2.87Å; H853-W855 VanDerWaalsContact C-N 3.31Å; H853-W855 PolarHBondContact O-N 3.35Å; H853-A856 WeakPolarHBondContact O-CB 3.38Å; H853-A856 PolarHBondContact O-N 3.04Å; H853-A856 VanDerWaalsContact O-N 3.08Å; H853-I857 WeakPolarHBondContact O-CG1 3.44Å; H853-I857 PolarHBondContact O-N 2.81Å
854D78.7Confident85.3Confident104 Ų10440.3 Ų40.356%0.55619%0.186SC*.Hα-helixtrans-66.8-34.7-175.7-56.9-24.1000112.3Y852 K858Y852-D854 PolarHBondContact O-N 3.15Å; D854-K858 WeakPolarHBondContact O-CB 3.48Å; D854-K858 VanDerWaalsContact O-CG 3.32Å; D854-K858 WeakPolarHBondContact O-CG 3.36Å; D854-K858 PolarHBondContact O-N 3.14Å; D854-K858 VanDerWaalsContact O-N 3.11Å
855W86.5Confident84.6Confident27 Ų2742.7 Ų42.710%0.10221%0.21CC..Hα-helixtrans-61.8-48.4171.3168.379000110.6V709 H711 I722 L724 Y852 H853 I857 K858 T859V709-W855 HydrophobicContact CG1-CZ2 4.39Å; H711-W855 HydrophobicContact CB-CD2 4.1Å; H711-W855 HydrophobicContact CB-CH2 4.15Å; H711-W855 HydrophobicContact CB-CZ2 3.58Å; H711-W855 AromaticContact CD2-CD1 3.85Å; H711-W855 AromaticContact CD2-CG 3.84Å; H711-W855 AromaticContact CE1-CD1 3.81Å; H711-W855 AromaticContact CG-CD1 3.76Å; H711-W855 AromaticContact CG-CE2 3.76Å; H711-W855 AromaticContact CG-NE1 3.54Å; H711-W855 AromaticContact ND1-CD1 3.71Å; H711-W855 AromaticContact ND1-NE1 3.6Å; H711-W855 AromaticContact NE2-CD1 3.91Å; I722-W855 HydrophobicContact CB-CZ3 4.44Å; I722-W855 HydrophobicContact CD1-CZ3 3.77Å; I722-W855 HydrophobicContact CG1-CH2 4.19Å; I722-W855 HydrophobicContact CG1-CZ3 3.83Å; I722-W855 HydrophobicContact CG2-CH2 3.94Å; I722-W855 HydrophobicContact CG2-CZ3 3.81Å; L724-W855 HydrophobicContact CD1-CE3 4.42Å; L724-W855 HydrophobicContact CD1-CH2 3.56Å; L724-W855 HydrophobicContact CD1-CZ3 3.42Å; L724-W855 VanDerWaalsContact CD1-CZ3 3.42Å; Y852-W855 HydrophobicContact CD1-CE3 4.09Å; Y852-W855 PolarHBondContact O-N 3.47Å; H853-W855 VanDerWaalsContact C-N 3.31Å; H853-W855 PolarHBondContact O-N 3.35Å; W855-I857 PolarHBondContact O-N 3.22Å; W855-K858 PolarHBondContact O-N 3.33Å; W855-T859 HydrophobicContact CZ2-CG2 4.27Å; W855-T859 PolarHBondContact NE1-OG1 3.22Å; W855-T859 VanDerWaalsContact O-CB 3.27Å; W855-T859 WeakPolarHBondContact O-CB 3.36Å; W855-T859 PolarHBondContact O-N 2.67Å; W855-T859 PolarHBondContact O-OG1 3.42Å; W855-T859 VanDerWaalsContact O-OG1 3.08Å
856A86.5Confident84Confident0 Ų043.2 Ų43.20%022%0.218CC..Hα-helixtrans-60.6-45.3-179.800000111.7L724 L742 M849 Y852 H853 T859 M860L724-A856 HydrophobicContact CD1-CB 4.42Å; L724-A856 HydrophobicContact CD2-CB 4.13Å; L724-A856 WeakPolarHBondContact CD2-O 3.14Å; L742-A856 HydrophobicContact CD2-CB 3.94Å; M849-A856 HydrophobicContact CE-CB 3.9Å; Y852-A856 WeakPolarHBondContact O-CB 3.43Å; Y852-A856 PolarHBondContact O-N 3.49Å; H853-A856 WeakPolarHBondContact O-CB 3.38Å; H853-A856 PolarHBondContact O-N 3.04Å; H853-A856 VanDerWaalsContact O-N 3.08Å; A856-T859 PolarHBondContact O-N 3.14Å; A856-M860 WeakPolarHBondContact O-CG 3.02Å; A856-M860 PolarHBondContact O-N 2.88Å
857I81.8Confident83.3Confident71 Ų7147.6 Ų47.636%0.36425%0.246SC..Hα-helixtrans-57.7-51.8176.1-60.7-52.6000111H853 W855 T859 M860 E861H853-I857 WeakPolarHBondContact O-CG1 3.44Å; H853-I857 PolarHBondContact O-N 2.81Å; W855-I857 PolarHBondContact O-N 3.22Å; I857-T859 VanDerWaalsContact C-N 3.34Å; I857-T859 PolarHBondContact O-N 3.36Å; I857-M860 HydrophobicContact CD1-CE 3.43Å; I857-M860 VanDerWaalsContact CD1-CE 3.43Å; I857-M860 HydrophobicContact CG1-CE 4.48Å; I857-M860 PolarHBondContact O-N 3.07Å; I857-E861 PolarHBondContact O-N 3.07Å
858K78.1Confident83Confident137 Ų13750.3 Ų50.360%0.59626%0.261SS*.Hα-helixtrans-62.1-40.8179.2-71.1175.3-179-178.30112.3D854 W855 E861 Q862D854-K858 WeakPolarHBondContact O-CB 3.48Å; D854-K858 VanDerWaalsContact O-CG 3.32Å; D854-K858 WeakPolarHBondContact O-CG 3.36Å; D854-K858 PolarHBondContact O-N 3.14Å; D854-K858 VanDerWaalsContact O-N 3.11Å; W855-K858 PolarHBondContact O-N 3.33Å; K858-E861 PolarHBondContact O-N 3.08Å; K858-Q862 WeakPolarHBondContact O-CG 3.46Å; K858-Q862 PolarHBondContact O-N 3.26Å; K858-Q862 VanDerWaalsContact O-N 3.14Å
859T84.5Confident82.7Confident2 Ų252.1 Ų52.11%0.01227%0.271CS..Hα-helixtrans-68.5-33.8179.9-68.90000112.4V709 L724 W855 A856 I857 E861 Q862 L863V709-T859 HydrophobicContact CB-CG2 3.59Å; V709-T859 HydrophobicContact CG1-CG2 3.65Å; V709-T859 HydrophobicContact CG2-CG2 4.27Å; L724-T859 HydrophobicContact CB-CG2 4.13Å; L724-T859 HydrophobicContact CD2-CG2 3.9Å; W855-T859 HydrophobicContact CZ2-CG2 4.27Å; W855-T859 PolarHBondContact NE1-OG1 3.22Å; W855-T859 VanDerWaalsContact O-CB 3.27Å; W855-T859 WeakPolarHBondContact O-CB 3.36Å; W855-T859 PolarHBondContact O-N 2.67Å; W855-T859 PolarHBondContact O-OG1 3.42Å; W855-T859 VanDerWaalsContact O-OG1 3.08Å; A856-T859 PolarHBondContact O-N 3.14Å; I857-T859 VanDerWaalsContact C-N 3.34Å; I857-T859 PolarHBondContact O-N 3.36Å; T859-E861 VanDerWaalsContact C-N 3.28Å; T859-E861 PolarHBondContact O-N 2.92Å; T859-Q862 PolarHBondContact O-N 3.24Å; T859-L863 HydrophobicContact CG2-CD1 3.89Å; T859-L863 HydrophobicContact CG2-CG 4.17Å; T859-L863 WeakPolarHBondContact O-CB 3.5Å; T859-L863 VanDerWaalsContact O-CG 3.3Å; T859-L863 WeakPolarHBondContact O-CG 3.41Å; T859-L863 PolarHBondContact O-N 3.49Å
860M83.9Confident82.4Confident18 Ų1852.6 Ų52.69%0.08927%0.274CS..Hα-helixtrans-59.7-38.9173.1-74.5-170.8-69.700112.3I654 I664 L724 A856 I857 R864I654-M860 HydrophobicContact CD1-SD 3.92Å; I664-M860 HydrophobicContact CB-CG 4.49Å; I664-M860 HydrophobicContact CB-SD 4.2Å; I664-M860 HydrophobicContact CD1-CG 4.11Å; I664-M860 HydrophobicContact CG1-CG 3.9Å; I664-M860 HydrophobicContact CG1-SD 3.86Å; I664-M860 HydrophobicContact CG2-CG 4.02Å; I664-M860 HydrophobicContact CG2-SD 4.04Å; L724-M860 HydrophobicContact CD2-CG 3.76Å; A856-M860 WeakPolarHBondContact O-CG 3.02Å; A856-M860 PolarHBondContact O-N 2.88Å; I857-M860 HydrophobicContact CD1-CE 3.43Å; I857-M860 VanDerWaalsContact CD1-CE 3.43Å; I857-M860 HydrophobicContact CG1-CE 4.48Å; I857-M860 PolarHBondContact O-N 3.07Å; M860-R864 PolarHBondContact O-N 3.27Å
861E78Confident82Confident94 Ų9459.5 Ų59.544%0.43930%0.304SS..Hα-helixtrans-68.6-42.5175.7-57.6-164.2124.200112.1R87 I857 K858 T859 R864 G865R87-E861 IonicContact CZ-OE1 3.9Å; R87-E861 IonicContact NH1-OE1 3.4Å; R87-E861 PolarHBondContact NH1-OE1 2.84Å; R87-E861 IonicContact NH2-OE1 3.99Å; R87-E861 PolarHBondContact NH2-OE1 3.23Å; I857-E861 PolarHBondContact O-N 3.07Å; K858-E861 PolarHBondContact O-N 3.08Å; T859-E861 VanDerWaalsContact C-N 3.28Å; T859-E861 PolarHBondContact O-N 2.92Å; E861-R864 WeakPolarHBondContact O-CB 3.3Å; E861-R864 PolarHBondContact O-N 3.47Å; E861-G865 PolarHBondContact O-N 3.33Å
862Q79.4Confident80.9Confident104 Ų10459.9 Ų59.949%0.48631%0.308SS..Hα-helixtrans-60-47175.8-69.9172.7-12.200111.8K858 T859 R864 G865 A866K858-Q862 WeakPolarHBondContact O-CG 3.46Å; K858-Q862 PolarHBondContact O-N 3.26Å; K858-Q862 VanDerWaalsContact O-N 3.14Å; T859-Q862 PolarHBondContact O-N 3.24Å; Q862-R864 PolarHBondContact O-N 3.49Å; Q862-G865 PolarHBondContact O-N 2.95Å; Q862-A866 WeakPolarHBondContact O-CB 3.44Å; Q862-A866 PolarHBondContact O-N 3.37Å
863L82.5Confident79.2Confident1 Ų166.3 Ų66.31%0.00534%0.342CS..Hα-helixtrans-60.9-31.2178.4-73.7167.5000112.4I664 N707 V709 L724 R726 T859 A866I664-L863 HydrophobicContact CD1-CD1 4.46Å; N707-L863 HydrophobicContact CB-CD2 4.45Å; N707-L863 PolarHBondContact ND2-O 3.41Å; N707-L863 WeakPolarHBondContact OD1-CD2 3.07Å; V709-L863 HydrophobicContact CB-CD2 4.21Å; V709-L863 HydrophobicContact CG2-CD2 3.66Å; V709-L863 HydrophobicContact CG2-CG 4.14Å; L724-L863 HydrophobicContact CB-CD1 3.7Å; R726-L863 HydrophobicContact CB-CB 4.09Å; R726-L863 HydrophobicContact CB-CD1 4.35Å; R726-L863 VanDerWaalsContact CD-O 3.25Å; R726-L863 WeakPolarHBondContact CD-O 3.3Å; T859-L863 HydrophobicContact CG2-CD1 3.89Å; T859-L863 HydrophobicContact CG2-CG 4.17Å; T859-L863 WeakPolarHBondContact O-CB 3.5Å; T859-L863 VanDerWaalsContact O-CG 3.3Å; T859-L863 WeakPolarHBondContact O-CG 3.41Å; T859-L863 PolarHBondContact O-N 3.49Å; L863-A866 PolarHBondContact O-N 3.41Å
864R77.8Confident77.4Confident105 Ų10567 Ų6740%0.39635%0.351SS..Hα-helixtrans-65.6-43.6177.7-171.6-178.6-67.7-179.9-0.1112M860 E861 Q862M860-R864 PolarHBondContact O-N 3.27Å; E861-R864 WeakPolarHBondContact O-CB 3.3Å; E861-R864 PolarHBondContact O-N 3.47Å; Q862-R864 PolarHBondContact O-N 3.49Å
865G74.7Confident75.8Confident50 Ų5069.5 Ų69.552%0.51537%0.365SS..Hα-helixtrans-79.9-19.8176.500000114.2E861 Q862E861-G865 PolarHBondContact O-N 3.33Å; Q862-G865 PolarHBondContact O-N 2.95Å
866A79.1Confident73.7Confident29 Ų2970.1 Ų70.124%0.2438%0.379CS..SBendtrans-67.5148.7-177.100000113.2R706 N707 Q862 L863R706-A866 PolarHBondContact NH2-O 3.22Å; N707-A866 WeakPolarHBondContact ND2-CB 3.17Å; N707-A866 PolarHBondContact ND2-O 3.35Å; Q862-A866 WeakPolarHBondContact O-CB 3.44Å; Q862-A866 PolarHBondContact O-N 3.37Å; L863-A866 PolarHBondContact O-N 3.41Å
867P80.3Confident71.6Confident91 Ų9175.3 Ų75.359%0.59141%0.411SS*.  trans-60.7151.3178.824.9-33.9000111.7N707 Q869N707-P867 PolarHBondContact ND2-O 2.69Å; P867-Q869 PolarHBondContact O-N 2.79Å
868D85.7Confident69.3Low61 Ų6179.4 Ų79.433%0.32643%0.426SS..  trans-74113.1171.1-177.1-0.5000109.5R706 S870R706-D868 HydrophobicContact CG-CB 3.84Å; D868-S870 VanDerWaalsContact CG-OG 3.26Å; D868-S870 WeakPolarHBondContact OD1-CB 3.43Å; D868-S870 PolarHBondContact OD1-N 3.08Å; D868-S870 PolarHBondContact OD1-OG 3.27Å; D868-S870 PolarHBondContact OD2-OG 3.28Å
869Q86.6Confident67.5Low83 Ų8378.3 Ų78.339%0.38843%0.426SS..  trans-100.17.1179.1-69.4179-27.400112.4P681 R706 P867 K871 T872P681-Q869 HydrophobicContact CB-CB 4.48Å; P681-Q869 HydrophobicContact CG-CB 3.81Å; R706-Q869 CarbonylContact O-C 3.57Å; R706-Q869 WeakPolarHBondContact O-CA 3.26Å; R706-Q869 PolarHBondContact O-N 3.46Å; P867-Q869 PolarHBondContact O-N 2.79Å; Q869-K871 PolarHBondContact O-N 3.12Å; Q869-K871 VanDerWaalsContact O-N 3.17Å; Q869-T872 WeakPolarHBondContact CA-OG1 3.17Å; Q869-T872 PolarHBondContact O-N 3.34Å; Q869-T872 PolarHBondContact O-OG1 2.87Å
870S82.6Confident65.2Low10 Ų1089.3 Ų89.37%0.0747%0.467CS..THydrogen-bonded Turntrans-64.4-18.9-179.266.30000114.3R682 V705 R706 D868R682-S870 VanDerWaalsContact CB-O 3.32Å; R682-S870 WeakPolarHBondContact CB-O 3.28Å; R682-S870 WeakPolarHBondContact CG-O 3.34Å; V705-S870 VanDerWaalsContact O-CB 3.28Å; V705-S870 WeakPolarHBondContact O-CB 3.24Å; R706-S870 PolarHBondContact O-N 3.07Å; D868-S870 VanDerWaalsContact CG-OG 3.26Å; D868-S870 WeakPolarHBondContact OD1-CB 3.43Å; D868-S870 PolarHBondContact OD1-N 3.08Å; D868-S870 PolarHBondContact OD1-OG 3.27Å; D868-S870 PolarHBondContact OD2-OG 3.28Å
871K76.9Confident63.3Low161 Ų16193.8 Ų93.870%0.749%0.486SS*.THydrogen-bonded Turntrans-105.4-6.6178.6-65.9-173-179.7-179.90113.8Q869 L873Q869-K871 PolarHBondContact O-N 3.12Å; Q869-K871 VanDerWaalsContact O-N 3.17Å; K871-L873 PolarHBondContact O-N 3.13Å; K871-L873 VanDerWaalsContact O-N 3.15Å
872T64.2Low61.4Low60 Ų6095.7 Ų95.737%0.36850%0.499SS..  trans-68.6115.3-172.7-48.10000110.2S680 Q869 S874S680-T872 PolarHBondContact OG-O 3.48Å; Q869-T872 WeakPolarHBondContact CA-OG1 3.17Å; Q869-T872 PolarHBondContact O-N 3.34Å; Q869-T872 PolarHBondContact O-OG1 2.87Å; T872-S874 PolarHBondContact O-N 3.12Å
873L49.8Very low59.8Low143 Ų14397.2 Ų97.275%0.74951%0.506SS*.  trans-82.911.1177.4-100.8143.1000113K871 D875K871-L873 PolarHBondContact O-N 3.13Å; K871-L873 VanDerWaalsContact O-N 3.15Å; L873-D875 PolarHBondContact O-N 3.23Å
874S48.9Very low57.9Low55 Ų55104 Ų10439%0.38554%0.536SS..  trans-58.7113.2-174.4580000109.3T872 G876T872-S874 PolarHBondContact O-N 3.12Å; S874-G876 PolarHBondContact O-N 2.91Å
875D44.1Very low56.3Low158 Ų158102.1 Ų102.185%0.84554%0.536SS*.  trans-40.1113.3153.2-73.7-36.6000105.8L873 V877L873-D875 PolarHBondContact O-N 3.23Å; D875-V877 PolarHBondContact O-N 3.47Å
876G41.5Very low54.7Low39 Ų39106.9 Ų106.940%0.40255%0.548SS..  trans-39.9125.2-159.600000111.2S874 K878S874-G876 PolarHBondContact O-N 2.91Å; G876-K878 PolarHBondContact O-N 2.9Å
877V42.3Very low53Low110 Ų110108.7 Ų108.767%0.66756%0.556SS**  trans-56.697.6177.3-179.40000106.7D875 I879D875-V877 PolarHBondContact O-N 3.47Å; V877-I879 HydrophobicContact CG1-CD1 4.42Å; V877-I879 HydrophobicContact CG1-CG1 3.73Å; V877-I879 PolarHBondContact O-N 2.74Å
878K35.3Very low50.9Low157 Ų157110 Ų11068%0.68356%0.564SS**  trans-75.782.8175.7-78.3-177.3-178.7174.90106.1T677 G876 R880T677-K878 HydrophobicContact CG2-CG 3.8Å; G876-K878 PolarHBondContact O-N 2.9Å; K878-R880 PolarHBondContact O-N 3.03Å
879I39.9Very low48.8Very low114 Ų114109.9 Ų109.959%0.58558%0.578SS**  trans-70.388.3162.5-48-178.9000105.9V877 F881V877-I879 HydrophobicContact CG1-CD1 4.42Å; V877-I879 HydrophobicContact CG1-CG1 3.73Å; V877-I879 PolarHBondContact O-N 2.74Å; I879-F881 HydrophobicContact CB-CD2 4.42Å; I879-F881 HydrophobicContact CB-CE2 3.88Å; I879-F881 HydrophobicContact CB-CZ 4.31Å; I879-F881 HydrophobicContact CG2-CD1 4.42Å; I879-F881 HydrophobicContact CG2-CD2 3.92Å; I879-F881 HydrophobicContact CG2-CE1 3.94Å; I879-F881 HydrophobicContact CG2-CE2 3.38Å; I879-F881 HydrophobicContact CG2-CG 4.42Å; I879-F881 HydrophobicContact CG2-CZ 3.4Å; I879-F881 WeakPolarHBondContact O-CD2 2.97Å; I879-F881 PolarHBondContact O-N 3.23Å; I879-F881 VanDerWaalsContact O-N 3.08Å
880R34.7Very low46.7Very low233 Ų233107.8 Ų107.888%0.87957%0.569SS**  trans-69.5101168.3-93.1-174.4174.5170.2-1.6107.1K878K878-R880 PolarHBondContact O-N 3.03Å
881F44.4Very low44.9Very low111 Ų111111.7 Ų111.749%0.48759%0.589SS.*  trans-78.8122.7159.6-62.6-82.4000107.4I879 Q883 A905I879-F881 HydrophobicContact CB-CD2 4.42Å; I879-F881 HydrophobicContact CB-CE2 3.88Å; I879-F881 HydrophobicContact CB-CZ 4.31Å; I879-F881 HydrophobicContact CG2-CD1 4.42Å; I879-F881 HydrophobicContact CG2-CD2 3.92Å; I879-F881 HydrophobicContact CG2-CE1 3.94Å; I879-F881 HydrophobicContact CG2-CE2 3.38Å; I879-F881 HydrophobicContact CG2-CG 4.42Å; I879-F881 HydrophobicContact CG2-CZ 3.4Å; I879-F881 WeakPolarHBondContact O-CD2 2.97Å; I879-F881 PolarHBondContact O-N 3.23Å; I879-F881 VanDerWaalsContact O-N 3.08Å; F881-Q883 PolarHBondContact O-N 2.95Å; F881-Q883 VanDerWaalsContact O-N 3.16Å; F881-A905 HydrophobicContact CB-CB 3.9Å; F881-A905 HydrophobicContact CD1-CB 3.86Å; F881-A905 HydrophobicContact CG-CB 4.09Å
882D37.9Very low43.6Very low135 Ų135109 Ų10972%0.72259%0.59SS**  trans-56.3123.7170.7-113.8-28.6000108.1K884D882-K884 PolarHBondContact O-N 2.83Å
883Q47.3Very low42.7Very low135 Ų135111.4 Ų111.463%0.63160%0.6SS**SBendtrans-62.6-10.2-170.9-78.7-174.7-24.200113.5F881F881-Q883 PolarHBondContact O-N 2.95Å; F881-Q883 VanDerWaalsContact O-N 3.16Å
884K41.4Very low42.4Very low145 Ų145106 Ų10663%0.6357%0.573SS**  trans-137.195.2177.3-64.2-173.6177.6177.20109.7D882 S902D882-K884 PolarHBondContact O-N 2.83Å; K884-S902 WeakPolarHBondContact CE-OG 3.4Å
885V44.5Very low42.3Very low64 Ų64106.1 Ų106.139%0.38857%0.572SS.*  trans-90.5114.2167-172.20000107.5V887 A905V885-V887 HydrophobicContact CB-CG2 4.48Å; V885-V887 HydrophobicContact CG1-CG2 3.58Å; V885-A905 HydrophobicContact CG2-CB 4.47Å
886I41.2Very low42.7Very low151 Ų151102.4 Ų102.477%0.77456%0.563SS**  trans-87.7104.5170.2-58.2174.6000106.5P888I886-P888 WeakPolarHBondContact O-CD 3.13Å
887V44.4Very low42.9Very low67 Ų67110.3 Ų110.341%0.40659%0.587SS.*  trans-101.1110.1174-1700000108.9V885 G889 L908V885-V887 HydrophobicContact CB-CG2 4.48Å; V885-V887 HydrophobicContact CG1-CG2 3.58Å; V887-G889 PolarHBondContact O-N 2.87Å; V887-L908 HydrophobicContact CG2-CD2 3.99Å
888P35.4Very low43Very low118 Ų118107.5 Ų107.577%0.76657%0.566SS**THydrogen-bonded Turntrans-60.7133.8174.6-19.932.2000110.8I886I886-P888 WeakPolarHBondContact O-CD 3.13Å
889G42Very low43.4Very low59 Ų59105.4 Ų105.461%0.60856%0.557SS**THydrogen-bonded Turntrans101.9-19.1179.800000115.6V887 L891 S892V887-G889 PolarHBondContact O-N 2.87Å; G889-L891 PolarHBondContact O-N 3.29Å; G889-S892 PolarHBondContact O-OG 2.9Å
890L42.6Very low43.6Very low39 Ų39106.4 Ų106.420%0.20457%0.569CS.*G310 helixtrans-73.3-9.7176.2-151.787.7000113.6S892 L893 L908L890-S892 PolarHBondContact O-N 3.19Å; L890-S892 VanDerWaalsContact O-N 3.08Å; L890-L893 HydrophobicContact CD1-CD1 4.14Å; L890-L893 HydrophobicContact CG-CD1 4.45Å; L890-L893 PolarHBondContact O-N 3.3Å; L890-L893 VanDerWaalsContact O-N 3.09Å; L890-L908 HydrophobicContact CD1-CD1 3.81Å; L890-L908 HydrophobicContact CD2-CD1 3.21Å; L890-L908 HydrophobicContact CG-CD1 4.14Å
891L44.4Very low44.3Very low92 Ų92101.9 Ų101.948%0.48256%0.556SS.*G310 helixtrans-60.2-13.4178-83.7154.1000114.1G889 K899G889-L891 PolarHBondContact O-N 3.29Å; L891-K899 HydrophobicContact CD2-CB 3.69Å; L891-K899 HydrophobicContact CD2-CD 3.88Å; L891-K899 HydrophobicContact CD2-CG 3.65Å; L891-K899 VanDerWaalsContact O-CE 3.32Å; L891-K899 WeakPolarHBondContact O-CE 3.34Å
892S48.7Very low44.6Very low104 Ų10499.7 Ų99.773%0.72755%0.554SS**G310 helixtrans-78.9-24.1174.959.80000113.4G889 L890G889-S892 PolarHBondContact O-OG 2.9Å; L890-S892 PolarHBondContact O-N 3.19Å; L890-S892 VanDerWaalsContact O-N 3.08Å
893L45.2Very low45.1Very low110 Ų11095.6 Ų95.658%0.57653%0.532SS*.SBendtrans-92.8-8.4-177.4-67.8167000113.2L890L890-L893 HydrophobicContact CD1-CD1 4.14Å; L890-L893 HydrophobicContact CG-CD1 4.45Å; L890-L893 PolarHBondContact O-N 3.3Å; L890-L893 VanDerWaalsContact O-N 3.09Å
894V44.4Very low45.5Very low30 Ų3090.5 Ų90.518%0.18251%0.511CS..SBendtrans-107.9122.2-177.3-175.20000109.6E898 L903V894-E898 HydrophobicContact CG1-CB 4.06Å; V894-L903 HydrophobicContact CG2-CD1 4.31Å
895P47.7Very low46.2Very low57 Ų5784.2 Ų84.237%0.3749%0.486SS..  trans-53.1141.7178.5-26.133.4000112.3K897 E898P895-K897 PolarHBondContact O-N 3.29Å; P895-E898 PolarHBondContact O-N 3.07Å
896A51Low46.7Very low80 Ų8083.1 Ų83.166%0.66148%0.48SS*.G310 helixtrans-52.3-30.4-166.900000115.2E898A896-E898 VanDerWaalsContact C-N 3.29Å; A896-E898 PolarHBondContact O-N 3.31Å
897K47Very low47.5Very low205 Ų20576.8 Ų76.889%0.89145%0.447SS*.G310 helixtrans-71.6-13.7179.6-74.7-175.4177.5178.10114.9P895P895-K897 PolarHBondContact O-N 3.29Å
898E44.1Very low48.1Very low52 Ų5274.9 Ų74.924%0.24343%0.434CS..G310 helixtrans-117.19.3-179.7-64.9-152.7126.900114.3V894 P895 A896 T900 K901 R918V894-E898 HydrophobicContact CG1-CB 4.06Å; P895-E898 PolarHBondContact O-N 3.07Å; A896-E898 VanDerWaalsContact C-N 3.29Å; A896-E898 PolarHBondContact O-N 3.31Å; E898-T900 PolarHBondContact O-N 3.31Å; E898-K901 PolarHBondContact O-N 3.17Å; E898-K901 IonicContact OE1-NZ 3.89Å; E898-K901 PolarHBondContact OE1-NZ 2.97Å; E898-R918 IonicContact OE2-CZ 2.7Å; E898-R918 IonicContact OE2-NH1 3.41Å; E898-R918 PolarHBondContact OE2-NH1 3.34Å; E898-R918 IonicContact OE2-NH2 3.48Å
899K44.1Very low49.1Very low113 Ų11373.4 Ų73.449%0.49142%0.418SS..THydrogen-bonded Turntrans-56.6-8.8-179.5-73.8-175.5170.5-176.80115.3L891L891-K899 HydrophobicContact CD2-CB 3.69Å; L891-K899 HydrophobicContact CD2-CD 3.88Å; L891-K899 HydrophobicContact CD2-CG 3.65Å; L891-K899 VanDerWaalsContact O-CE 3.32Å; L891-K899 WeakPolarHBondContact O-CE 3.34Å
900T43.7Very low49.8Very low135 Ų13570.7 Ų70.783%0.82839%0.391SS*.THydrogen-bonded Turntrans-99.2-4.2178.851.30000114.5E898E898-T900 PolarHBondContact O-N 3.31Å
901K48.4Very low50.3Low138 Ų13870.9 Ų70.960%0.639%0.393SS*.SBendtrans-98.6124.5-179.6-66.6-178-173.4167.80111.5E898E898-K901 PolarHBondContact O-N 3.17Å; E898-K901 IonicContact OE1-NZ 3.89Å; E898-K901 PolarHBondContact OE1-NZ 2.97Å
902S50.9Low50.7Low64 Ų6473.2 Ų73.245%0.44840%0.403SS..PPolyproline II helixtrans-65.9132.4174.154.40000111.9K884K884-S902 WeakPolarHBondContact CE-OG 3.4Å
903L49.5Very low50.8Low50 Ų5070.6 Ų70.626%0.26239%0.385SS..PPolyproline II helixtrans-84.2146.8169.5-88.190.9000111.3V894 D907 V911V894-L903 HydrophobicContact CG2-CD1 4.31Å; L903-D907 HydrophobicContact CD2-CB 3.9Å; L903-D907 HydrophobicContact CG-CB 4.42Å; L903-V911 HydrophobicContact CD2-CG2 4.48Å
904S54.6Low51Low27 Ų2772 Ų7219%0.18939%0.393CS..PPolyproline II helixtrans-74.1155.7165.774.50000110.6V906 D907 L908S904-V906 PolarHBondContact O-N 3.31Å; S904-D907 PolarHBondContact O-N 3Å; S904-D907 PolarHBondContact OG-N 2.75Å; S904-D907 PolarHBondContact OG-OD2 3.03Å; S904-L908 PolarHBondContact O-N 3.31Å
905A56.3Low51.2Low13 Ų1376 Ų7611%0.10741%0.406CS..Hα-helixtrans-58.9-33.1177.400000113F881 V885 L908 M909F881-A905 HydrophobicContact CB-CB 3.9Å; F881-A905 HydrophobicContact CD1-CB 3.86Å; F881-A905 HydrophobicContact CG-CB 4.09Å; V885-A905 HydrophobicContact CG2-CB 4.47Å; A905-L908 WeakPolarHBondContact O-CB 3.48Å; A905-L908 PolarHBondContact O-N 3.07Å; A905-M909 PolarHBondContact O-N 2.79Å; A905-M909 VanDerWaalsContact O-N 3.07Å
906V55.6Low51Low42 Ų4275.3 Ų75.326%0.25540%0.397SS..Hα-helixtrans-68.9-45177-1790000110.9S904 L908 M909 A910S904-V906 PolarHBondContact O-N 3.31Å; V906-L908 VanDerWaalsContact C-N 3.26Å; V906-L908 PolarHBondContact O-N 2.02Å; V906-M909 PolarHBondContact O-N 2.98Å; V906-A910 WeakPolarHBondContact O-CB 3.48Å; V906-A910 PolarHBondContact O-N 3.24Å
907D57.1Low50.6Low18 Ų1880.8 Ų80.810%0.09641%0.406CS..Hα-helixtrans-62.4-37.3175.8-66.1-50.1000111.2K717 L903 S904 A910 V911K717-D907 VanDerWaalsContact NZ-CG 3.29Å; K717-D907 IonicContact NZ-OD1 3.32Å; K717-D907 PolarHBondContact NZ-OD1 3.27Å; K717-D907 IonicContact NZ-OD2 3.36Å; K717-D907 PolarHBondContact NZ-OD2 3.21Å; L903-D907 HydrophobicContact CD2-CB 3.9Å; L903-D907 HydrophobicContact CG-CB 4.42Å; S904-D907 PolarHBondContact O-N 3Å; S904-D907 PolarHBondContact OG-N 2.75Å; S904-D907 PolarHBondContact OG-OD2 3.03Å; D907-A910 PolarHBondContact O-N 2.75Å; D907-V911 WeakPolarHBondContact O-CG2 3.29Å; D907-V911 PolarHBondContact O-N 3.32Å
908L58.4Low50.1Low26 Ų2678.1 Ų78.114%0.13639%0.391CS..Hα-helixtrans-61.8-48176.1-175.866.9000111.6V887 L890 S904 A905 V906 A910 V911 M912V887-L908 HydrophobicContact CG2-CD2 3.99Å; L890-L908 HydrophobicContact CD1-CD1 3.81Å; L890-L908 HydrophobicContact CD2-CD1 3.21Å; L890-L908 HydrophobicContact CG-CD1 4.14Å; S904-L908 PolarHBondContact O-N 3.31Å; A905-L908 WeakPolarHBondContact O-CB 3.48Å; A905-L908 PolarHBondContact O-N 3.07Å; V906-L908 VanDerWaalsContact C-N 3.26Å; V906-L908 PolarHBondContact O-N 2.02Å; L908-A910 VanDerWaalsContact C-N 3.34Å; L908-A910 PolarHBondContact O-N 2.75Å; L908-V911 PolarHBondContact O-N 3.35Å; L908-M912 HydrophobicContact CG-SD 4.19Å; L908-M912 WeakPolarHBondContact O-CG 3.46Å; L908-M912 PolarHBondContact O-N 3.17Å
909M55.1Low49.4Very low87 Ų8780.9 Ų80.943%0.42942%0.416SS..Hα-helixtrans-64-37.3176.9-71.1-157-73.400112.6A905 V906 V911 M912 S913A905-M909 PolarHBondContact O-N 2.79Å; A905-M909 VanDerWaalsContact O-N 3.07Å; V906-M909 PolarHBondContact O-N 2.98Å; M909-V911 VanDerWaalsContact C-N 3.34Å; M909-M912 PolarHBondContact O-N 3.45Å; M909-S913 WeakPolarHBondContact O-CB 3.41Å; M909-S913 PolarHBondContact O-N 3.17Å; M909-S913 PolarHBondContact O-OG 2.88Å
910A56Low48.7Very low3 Ų382.3 Ų82.33%0.02543%0.427CS..Hα-helixtrans-67.9-32.1176.500000113V906 D907 L908 S913 Y915 H916V906-A910 WeakPolarHBondContact O-CB 3.48Å; V906-A910 PolarHBondContact O-N 3.24Å; D907-A910 PolarHBondContact O-N 2.75Å; L908-A910 VanDerWaalsContact C-N 3.34Å; L908-A910 PolarHBondContact O-N 2.75Å; A910-S913 WeakPolarHBondContact CA-OG 3.44Å; A910-S913 PolarHBondContact O-OG 2.7Å; A910-Y915 WeakPolarHBondContact O-CB 3.5Å; A910-Y915 PolarHBondContact O-N 3.21Å; A910-H916 VanDerWaalsContact CB-CD2 3.46Å; A910-H916 WeakPolarHBondContact CB-CD2 3.49Å; A910-H916 PolarHBondContact O-N 3.11Å
911V54.6Low48Very low43 Ų4383 Ų8326%0.26145%0.446SS..Hα-helixtrans-74.4-45.5172.5171.50000110.9L903 D907 L908 M909 S913 N914 H916L903-V911 HydrophobicContact CD2-CG2 4.48Å; D907-V911 WeakPolarHBondContact O-CG2 3.29Å; D907-V911 PolarHBondContact O-N 3.32Å; L908-V911 PolarHBondContact O-N 3.35Å; M909-V911 VanDerWaalsContact C-N 3.34Å; V911-S913 PolarHBondContact O-N 2.98Å; V911-N914 WeakPolarHBondContact O-CA 3.45Å; V911-N914 PolarHBondContact O-N 3.29Å; V911-H916 HydrophobicContact CG2-CB 4.16Å
912M51.5Low48Very low140 Ų14080.2 Ų80.269%0.6944%0.438SS*.Hα-helixtrans-63.1-29.1179.4-72.7-177.469.600113.3L908 M909 N914L908-M912 HydrophobicContact CG-SD 4.19Å; L908-M912 WeakPolarHBondContact O-CG 3.46Å; L908-M912 PolarHBondContact O-N 3.17Å; M909-M912 PolarHBondContact O-N 3.45Å; M912-N914 PolarHBondContact O-N 3.11Å
913S52.1Low47.8Very low49 Ų4981.1 Ų81.134%0.34344%0.438SS..THydrogen-bonded Turntrans-80.89.4172.753.40000113.9M909 A910 V911 Y915M909-S913 WeakPolarHBondContact O-CB 3.41Å; M909-S913 PolarHBondContact O-N 3.17Å; M909-S913 PolarHBondContact O-OG 2.88Å; A910-S913 WeakPolarHBondContact CA-OG 3.44Å; A910-S913 PolarHBondContact O-OG 2.7Å; V911-S913 PolarHBondContact O-N 2.98Å; S913-Y915 PolarHBondContact O-N 2.81Å; S913-Y915 VanDerWaalsContact O-N 3.17Å
914N48.3Very low47.7Very low139 Ų13982.8 Ų82.874%0.74345%0.448SS*.THydrogen-bonded Turntrans59.117.5-175.5-86.7-24.1000114.9V911 M912V911-N914 WeakPolarHBondContact O-CA 3.45Å; V911-N914 PolarHBondContact O-N 3.29Å; M912-N914 PolarHBondContact O-N 3.11Å
915Y48.8Very low47.3Very low115 Ų11586.1 Ų86.145%0.45146%0.463SS..  trans-84.4-41.3-171.6-115.5-90.9000113.4H711 A910 S913 K917H711-Y915 AromaticContact NE2-CE1 3.64Å; H711-Y915 AromaticContact NE2-CZ 3.69Å; A910-Y915 WeakPolarHBondContact O-CB 3.5Å; A910-Y915 PolarHBondContact O-N 3.21Å; S913-Y915 PolarHBondContact O-N 2.81Å; S913-Y915 VanDerWaalsContact O-N 3.17Å; Y915-K917 VanDerWaalsContact C-N 3.3Å; Y915-K917 PolarHBondContact O-N 3.24Å
916H43.6Very low46.7Very low43 Ų4390.6 Ų90.620%0.19949%0.485CS..  trans-77.184.1165.5-76.1-43.6000109.3D719 A910 V911 R918D719-H916 IonicContact OD2-CE1 2.77Å; D719-H916 PolarHBondContact OD2-CE1 2.77Å; A910-H916 VanDerWaalsContact CB-CD2 3.46Å; A910-H916 WeakPolarHBondContact CB-CD2 3.49Å; A910-H916 PolarHBondContact O-N 3.11Å; V911-H916 HydrophobicContact CG2-CB 4.16Å; H916-R918 PolarHBondContact O-N 3.28Å
917K43.8Very low46.2Very low195 Ų19593.9 Ų93.985%0.84850%0.501SS*.  trans-66.177156.2-72.9-171.7-178.8-1790108.1Y915 S919Y915-K917 VanDerWaalsContact C-N 3.3Å; Y915-K917 PolarHBondContact O-N 3.24Å; K917-S919 PolarHBondContact O-N 3.13Å
918R35.5Very low45.4Very low148 Ų14899.3 Ų99.356%0.55853%0.529SS*.  trans-64.6117.8159.6-104.2-178.1169.6-164.7-8.5105E898 H916 I920E898-R918 IonicContact OE2-CZ 2.7Å; E898-R918 IonicContact OE2-NH1 3.41Å; E898-R918 PolarHBondContact OE2-NH1 3.34Å; E898-R918 IonicContact OE2-NH2 3.48Å; H916-R918 PolarHBondContact O-N 3.28Å; R918-I920 PolarHBondContact O-N 2.75Å
919S30.3Very low44.4Very low110 Ų110104.9 Ų104.977%0.76956%0.56SS**  trans-50.6110.8168.3176.10000107.1K917 A921K917-S919 PolarHBondContact O-N 3.13Å; S919-A921 VanDerWaalsContact C-N 3.29Å; S919-A921 PolarHBondContact O-N 3.15Å
920I29.4Very low43.5Very low144 Ų144106.4 Ų106.474%0.73857%0.571SS**  trans-69.298.8167.4-56.9169.1000103.8R918R918-I920 PolarHBondContact O-N 2.75Å
921A27.9Very low42.3Very low148 Ų148115.8 Ų115.8100%1.22362%0.62SS**  trans-80.10165.300000109.1S919S919-A921 VanDerWaalsContact C-N 3.29Å; S919-A921 PolarHBondContact O-N 3.15Å

Retrieved 921 of 921 residues in 312.4 ms (Link to these results)