A0A077ZFG9_TRITR Loading...

Reverse transcriptase

AlphaFold DB , UniProt , Accession A0A077ZFG9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 281 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1K87.9Confident90.8Very high174 Ų17469.5 Ų69.576%0.75736%0.357SS*.  0-61.60-61.4-171.5-177.1-179.20112.7A3 L4 I5 N41K1-A3 PolarHBondContact O-N 3.25Å; K1-L4 WeakPolarHBondContact O-CB 3.26Å; K1-L4 PolarHBondContact O-N 3.26Å; K1-I5 PolarHBondContact O-N 3.2Å; K1-I5 VanDerWaalsContact O-N 3.13Å; K1-N41 WeakPolarHBondContact CD-OD1 3.49Å
2I87.7Confident91Very high25 Ų2578.9 Ų78.913%0.12839%0.385CS..Hα-helixtrans-64.1-39.4-177.7-66.1159.2000113.1L4 I5 R6 L42 L63 F168I2-L4 VanDerWaalsContact C-N 3.32Å; I2-L4 PolarHBondContact O-N 3.43Å; I2-I5 WeakPolarHBondContact O-CB 3.48Å; I2-I5 PolarHBondContact O-N 3.18Å; I2-I5 VanDerWaalsContact O-N 3.15Å; I2-R6 WeakPolarHBondContact O-CB 3.11Å; I2-R6 PolarHBondContact O-N 2.86Å; I2-L42 HydrophobicContact CD1-CD1 3.98Å; I2-L42 HydrophobicContact CD1-CD2 3.25Å; I2-L42 HydrophobicContact CD1-CG 3.51Å; I2-L63 HydrophobicContact CG2-CD2 4.4Å; I2-F168 HydrophobicContact CD1-CD1 4.5Å; I2-F168 HydrophobicContact CD1-CE1 3.79Å
3A88.1Confident91Very high49 Ų4974 Ų7441%0.40536%0.363SS..Hα-helixtrans-55.7-46.6173.600000111.6K1 I5 R6 E7K1-A3 PolarHBondContact O-N 3.25Å; A3-I5 VanDerWaalsContact C-N 3.34Å; A3-I5 PolarHBondContact O-N 2.92Å; A3-R6 PolarHBondContact O-N 3.38Å; A3-R6 VanDerWaalsContact O-N 3.12Å; A3-E7 WeakPolarHBondContact O-CB 3.35Å; A3-E7 WeakPolarHBondContact O-CG 3.49Å; A3-E7 PolarHBondContact O-N 3.04Å
4L90.6Very high91Very high108 Ų10869.6 Ų69.657%0.56534%0.342SS*.Hα-helixtrans-60-41.4175.8-62.8174.2000112.6K1 I2 R6 N8 L9K1-L4 WeakPolarHBondContact O-CB 3.26Å; K1-L4 PolarHBondContact O-N 3.26Å; I2-L4 VanDerWaalsContact C-N 3.32Å; I2-L4 PolarHBondContact O-N 3.43Å; L4-R6 VanDerWaalsContact C-N 3.33Å; L4-N8 WeakPolarHBondContact O-CA 3.44Å; L4-N8 WeakPolarHBondContact O-CB 3.29Å; L4-N8 PolarHBondContact O-N 3.41Å; L4-L9 PolarHBondContact O-N 3.44Å; L4-L9 VanDerWaalsContact O-N 3.16Å
5I92.2Very high90.9Very high14 Ų1475.3 Ų75.37%0.07236%0.359CS..Iπ-helixtrans-61-46.4175.6-67.1171.9000110K1 I2 A3 L9 I10 I34 T37 V38K1-I5 PolarHBondContact O-N 3.2Å; K1-I5 VanDerWaalsContact O-N 3.13Å; I2-I5 WeakPolarHBondContact O-CB 3.48Å; I2-I5 PolarHBondContact O-N 3.18Å; I2-I5 VanDerWaalsContact O-N 3.15Å; A3-I5 VanDerWaalsContact C-N 3.34Å; A3-I5 PolarHBondContact O-N 2.92Å; I5-L9 HydrophobicContact CG1-CD2 4.44Å; I5-L9 HydrophobicContact CG2-CD2 4.4Å; I5-L9 PolarHBondContact O-N 3.36Å; I5-I10 HydrophobicContact CG2-CD1 4.08Å; I5-I10 HydrophobicContact CG2-CG1 4.16Å; I5-I10 WeakPolarHBondContact O-CB 3.3Å; I5-I10 VanDerWaalsContact O-CG1 3.32Å; I5-I10 WeakPolarHBondContact O-CG1 3.46Å; I5-I10 PolarHBondContact O-N 3.45Å; I5-I34 HydrophobicContact CG2-CG2 3.92Å; I5-T37 HydrophobicContact CD1-CG2 4.15Å; I5-V38 HydrophobicContact CD1-CG2 3.89Å; I5-V38 HydrophobicContact CG2-CG2 4.45Å
6R90.1Very high90.8Very high69 Ų6978.6 Ų78.626%0.2637%0.374SS..Iπ-helixtrans-70.1-43.9-175.7-168.6-179.4-152.9176.92113.5I2 A3 L4 P11 T58 L63 G64 L65I2-R6 WeakPolarHBondContact O-CB 3.11Å; I2-R6 PolarHBondContact O-N 2.86Å; A3-R6 PolarHBondContact O-N 3.38Å; A3-R6 VanDerWaalsContact O-N 3.12Å; L4-R6 VanDerWaalsContact C-N 3.33Å; R6-P11 WeakPolarHBondContact O-CD 3.41Å; R6-T58 PolarHBondContact NH2-OG1 3.31Å; R6-L63 PolarHBondContact NH1-O 3.01Å; R6-L63 PolarHBondContact NH2-O 3.17Å; R6-G64 PolarHBondContact NE-O 3.05Å; R6-G64 VanDerWaalsContact NH2-CA 3.27Å; R6-G64 PolarHBondContact NH2-O 3.15Å; R6-L65 HydrophobicContact CB-CD2 4.11Å; R6-L65 HydrophobicContact CG-CD2 4.17Å
7E90.7Very high90.6Very high96 Ų9674.8 Ų74.845%0.44936%0.357SS..Iπ-helixtrans-92-29.3-169.6-64.3172.7170.900112.2A3 P11 R161A3-E7 WeakPolarHBondContact O-CB 3.35Å; A3-E7 WeakPolarHBondContact O-CG 3.49Å; A3-E7 PolarHBondContact O-N 3.04Å; E7-P11 WeakPolarHBondContact O-CG 3.39Å; E7-R161 IonicContact OE1-NH2 3.58Å; E7-R161 PolarHBondContact OE1-NH2 2.82Å; E7-R161 VanDerWaalsContact OE1-NH2 3.1Å
8N92.7Very high90.2Very high83 Ų8372.1 Ų72.144%0.44435%0.347SS..Iπ-helixtrans-115.8-50.8-175.2-61.5-61.2000113.6L4 R12L4-N8 WeakPolarHBondContact O-CA 3.44Å; L4-N8 WeakPolarHBondContact O-CB 3.29Å; L4-N8 PolarHBondContact O-N 3.41Å; N8-R12 WeakPolarHBondContact O-CG 3.43Å
9L93.3Very high89.7Confident80 Ų8075.2 Ų75.242%0.41936%0.36SS..Iπ-helixtrans-71.7-53.1-173.2-175.266.5000111.8L4 I5 R12 C13 I34L4-L9 PolarHBondContact O-N 3.44Å; L4-L9 VanDerWaalsContact O-N 3.16Å; I5-L9 HydrophobicContact CG1-CD2 4.44Å; I5-L9 HydrophobicContact CG2-CD2 4.4Å; I5-L9 PolarHBondContact O-N 3.36Å; L9-R12 WeakPolarHBondContact O-CB 3.08Å; L9-R12 PolarHBondContact O-N 3.4Å; L9-C13 PolarHBondContact O-N 3.36Å; L9-C13 PolarHBondContact O-SG 3.18Å; L9-C13 VanDerWaalsContact O-SG 3.36Å; L9-I34 HydrophobicContact CD2-CG1 4.43Å
10I93.1Very high88.9Confident4 Ų475.5 Ų75.52%0.02136%0.364CS..Hα-helixtrans-58.5-47.3-176.4-77.7178.2000112.2I5 R12 C13 I14 I34 L65 P66 L68I5-I10 HydrophobicContact CG2-CD1 4.08Å; I5-I10 HydrophobicContact CG2-CG1 4.16Å; I5-I10 WeakPolarHBondContact O-CB 3.3Å; I5-I10 VanDerWaalsContact O-CG1 3.32Å; I5-I10 WeakPolarHBondContact O-CG1 3.46Å; I5-I10 PolarHBondContact O-N 3.45Å; I10-R12 VanDerWaalsContact C-N 3.31Å; I10-R12 PolarHBondContact O-N 3.15Å; I10-C13 PolarHBondContact O-N 3.33Å; I10-I14 HydrophobicContact CG2-CD1 3.61Å; I10-I14 HydrophobicContact CG2-CG1 4.33Å; I10-I14 VanDerWaalsContact O-CG1 3.28Å; I10-I14 WeakPolarHBondContact O-CG1 3.16Å; I10-I14 PolarHBondContact O-N 2.84Å; I10-I34 HydrophobicContact CG1-CD1 4.29Å; I10-L65 HydrophobicContact CD1-CB 4.22Å; I10-L65 HydrophobicContact CD1-CD2 3.84Å; I10-P66 HydrophobicContact CD1-CG 4.47Å; I10-P66 HydrophobicContact CG2-CG 3.39Å; I10-L68 HydrophobicContact CG2-CD2 4.37Å
11P92.8Very high88Confident63 Ų6375.6 Ų75.641%0.40937%0.372SS..Hα-helixtrans-59.4-40.1177.2-29.239000113.4R6 E7 I14 Y15R6-P11 WeakPolarHBondContact O-CD 3.41Å; E7-P11 WeakPolarHBondContact O-CG 3.39Å; P11-I14 PolarHBondContact O-N 3.07Å; P11-Y15 PolarHBondContact O-N 2.91Å
12R92.6Very high86.9Confident182 Ų18268.5 Ų68.569%0.68734%0.344SS*.Hα-helixtrans-63.3-46.6175.3-72.4179.2176.7-164.1-0.6111.6N8 L9 I10 I14 Y15 Q16N8-R12 WeakPolarHBondContact O-CG 3.43Å; L9-R12 WeakPolarHBondContact O-CB 3.08Å; L9-R12 PolarHBondContact O-N 3.4Å; I10-R12 VanDerWaalsContact C-N 3.31Å; I10-R12 PolarHBondContact O-N 3.15Å; R12-I14 PolarHBondContact O-N 2.94Å; R12-Y15 PolarHBondContact O-N 3.09Å; R12-Q16 PolarHBondContact O-N 2.99Å
13C91.3Very high85.9Confident15 Ų1572.8 Ų72.810%0.10136%0.363CS..Hα-helixtrans-60.4-44.2176-66.10000111.7L9 I10 Y15 Q16 L17 L68L9-C13 PolarHBondContact O-N 3.36Å; L9-C13 PolarHBondContact O-SG 3.18Å; L9-C13 VanDerWaalsContact O-SG 3.36Å; I10-C13 PolarHBondContact O-N 3.33Å; C13-Y15 VanDerWaalsContact C-N 3.31Å; C13-Y15 PolarHBondContact O-N 3.26Å; C13-Q16 PolarHBondContact O-N 2.64Å; C13-L17 HydrophobicContact CB-CD1 4.36Å; C13-L17 WeakPolarHBondContact O-CB 3.47Å; C13-L17 WeakPolarHBondContact O-CD1 3.38Å; C13-L17 WeakPolarHBondContact O-CG 3.38Å; C13-L17 PolarHBondContact O-N 3.47Å; C13-L68 HydrophobicContact CB-CD1 4.17Å; C13-L68 HydrophobicContact CB-CD2 4.29Å
14I90.5Very high85.1Confident13 Ų1372.8 Ų72.87%0.06736%0.361CS..Hα-helixtrans-60.9-43178.2-69.8165.1000110.7I10 P11 R12 S18 P66 L68 V71 K75I10-I14 HydrophobicContact CG2-CD1 3.61Å; I10-I14 HydrophobicContact CG2-CG1 4.33Å; I10-I14 VanDerWaalsContact O-CG1 3.28Å; I10-I14 WeakPolarHBondContact O-CG1 3.16Å; I10-I14 PolarHBondContact O-N 2.84Å; P11-I14 PolarHBondContact O-N 3.07Å; R12-I14 PolarHBondContact O-N 2.94Å; I14-S18 WeakPolarHBondContact O-CB 3.46Å; I14-S18 PolarHBondContact O-N 2.77Å; I14-S18 PolarHBondContact O-OG 3.01Å; I14-P66 HydrophobicContact CD1-CG 4.13Å; I14-L68 HydrophobicContact CD1-CD2 4.31Å; I14-L68 HydrophobicContact CG1-CD2 3.61Å; I14-V71 HydrophobicContact CD1-CG1 3.93Å; I14-V71 HydrophobicContact CG1-CG1 4.18Å; I14-V71 HydrophobicContact CG2-CG1 3.99Å; I14-K75 HydrophobicContact CG2-CD 3.63Å
15Y89.4Confident84.8Confident155 Ų15572.2 Ų72.261%0.60836%0.361SS*.Hα-helixtrans-59.8-54.9177.2179-96.5000110.7P11 R12 C13 L17 S18 H19P11-Y15 PolarHBondContact O-N 2.91Å; R12-Y15 PolarHBondContact O-N 3.09Å; C13-Y15 VanDerWaalsContact C-N 3.31Å; C13-Y15 PolarHBondContact O-N 3.26Å; Y15-L17 PolarHBondContact O-N 3.3Å; Y15-S18 PolarHBondContact O-N 2.97Å; Y15-S18 PolarHBondContact O-OG 3.33Å; Y15-H19 AromaticContact CD2-CE1 3.75Å; Y15-H19 AromaticContact CE2-CE1 3.45Å; Y15-H19 VanDerWaalsContact CE2-CE1 3.45Å; Y15-H19 WeakPolarHBondContact CE2-CE1 3.35Å; Y15-H19 AromaticContact CZ-CE1 3.6Å; Y15-H19 PolarHBondContact O-CE1 3.43Å; Y15-H19 PolarHBondContact O-ND1 3.08Å
16Q89.2Confident84.6Confident127 Ų12774.5 Ų74.559%0.59337%0.374SS*.Hα-helixtrans-60.2-48.9-179.3-69175.6-30.700112R12 C13 S18 H19 L20R12-Q16 PolarHBondContact O-N 2.99Å; C13-Q16 PolarHBondContact O-N 2.64Å; Q16-S18 VanDerWaalsContact C-N 3.27Å; Q16-S18 PolarHBondContact O-N 3.32Å; Q16-H19 PolarHBondContact O-N 3Å; Q16-L20 WeakPolarHBondContact O-CG 3.29Å; Q16-L20 PolarHBondContact O-N 3.11Å
17L88.6Confident84.6Confident15 Ų1571.6 Ų71.68%0.07936%0.364CS..Hα-helixtrans-67.3-25.1-178.5-68168000113.5C13 Y15 H19 L20 L26 A27 L68 T72C13-L17 HydrophobicContact CB-CD1 4.36Å; C13-L17 WeakPolarHBondContact O-CB 3.47Å; C13-L17 WeakPolarHBondContact O-CD1 3.38Å; C13-L17 WeakPolarHBondContact O-CG 3.38Å; C13-L17 PolarHBondContact O-N 3.47Å; Y15-L17 PolarHBondContact O-N 3.3Å; L17-H19 VanDerWaalsContact C-N 3.27Å; L17-H19 PolarHBondContact O-N 3.42Å; L17-L20 HydrophobicContact CD2-CD1 4.21Å; L17-L20 PolarHBondContact O-N 3.04Å; L17-L26 HydrophobicContact CD2-CB 4.46Å; L17-L26 HydrophobicContact CD2-CD2 3.89Å; L17-L26 HydrophobicContact CD2-CG 3.99Å; L17-A27 HydrophobicContact CD1-CB 4.14Å; L17-A27 HydrophobicContact CD2-CB 4.25Å; L17-L68 HydrophobicContact CD1-CB 4.22Å; L17-L68 HydrophobicContact CD1-CD1 3.96Å; L17-T72 HydrophobicContact CB-CG2 3.42Å; L17-T72 VanDerWaalsContact CB-CG2 3.42Å; L17-T72 HydrophobicContact CD1-CG2 4.17Å; L17-T72 HydrophobicContact CG-CG2 4.45Å
18S83.7Confident84.5Confident25 Ų2569.1 Ų69.118%0.17536%0.358CS..Hα-helixtrans-71.5-21.6177.9660000114I14 Y15 Q16 T76I14-S18 WeakPolarHBondContact O-CB 3.46Å; I14-S18 PolarHBondContact O-N 2.77Å; I14-S18 PolarHBondContact O-OG 3.01Å; Y15-S18 PolarHBondContact O-N 2.97Å; Y15-S18 PolarHBondContact O-OG 3.33Å; Q16-S18 VanDerWaalsContact C-N 3.27Å; Q16-S18 PolarHBondContact O-N 3.32Å; S18-T76 PolarHBondContact O-OG1 2.83Å
19H80.4Confident84.5Confident131 Ų13170.1 Ų70.161%0.60636%0.36SS*.Hα-helixtrans-93.7-18.5176.2-6092000112.7Y15 Q16 L17Y15-H19 AromaticContact CD2-CE1 3.75Å; Y15-H19 AromaticContact CE2-CE1 3.45Å; Y15-H19 VanDerWaalsContact CE2-CE1 3.45Å; Y15-H19 WeakPolarHBondContact CE2-CE1 3.35Å; Y15-H19 AromaticContact CZ-CE1 3.6Å; Y15-H19 PolarHBondContact O-CE1 3.43Å; Y15-H19 PolarHBondContact O-ND1 3.08Å; Q16-H19 PolarHBondContact O-N 3Å; L17-H19 VanDerWaalsContact C-N 3.27Å; L17-H19 PolarHBondContact O-N 3.42Å
20L73.3Confident84.4Confident82 Ų8268 Ų6843%0.42935%0.35SS..SBendtrans-77.8163.9175.2-65.9174.6000111Q16 L17 L26Q16-L20 WeakPolarHBondContact O-CG 3.29Å; Q16-L20 PolarHBondContact O-N 3.11Å; L17-L20 HydrophobicContact CD2-CD1 4.21Å; L17-L20 PolarHBondContact O-N 3.04Å; L20-L26 HydrophobicContact CD1-CD2 3.71Å
21S71Confident84.4Confident78 Ų7868 Ų6855%0.54535%0.35SS..  trans-54.2123.7178.71780000110.7Q23 S24S21-Q23 PolarHBondContact O-N 3Å; S21-S24 VanDerWaalsContact O-CB 3.27Å; S21-S24 WeakPolarHBondContact O-CB 3.21Å; S21-S24 PolarHBondContact O-N 3.4Å
22P63.9Low84.3Confident25 Ų2569.6 Ų69.616%0.16235%0.352CS..THydrogen-bonded Turntrans-63.8-16.9-175.520.5-30.3000114S24 T76 A103 L107P22-S24 VanDerWaalsContact C-N 3.31Å; P22-T76 HydrophobicContact CB-CG2 4.07Å; P22-T76 HydrophobicContact CG-CG2 4.1Å; P22-A103 HydrophobicContact CG-CB 4.3Å; P22-L107 HydrophobicContact CB-CD1 3.73Å; P22-L107 HydrophobicContact CB-CD2 3.85Å; P22-L107 HydrophobicContact CB-CG 4.05Å; P22-L107 HydrophobicContact CG-CD1 3.98Å; P22-L107 HydrophobicContact CG-CG 4.43Å
23Q66.4Low84.3Confident114 Ų11465.7 Ų65.753%0.53334%0.344SS..THydrogen-bonded Turntrans-85.3-4.8179.2-61.3179.62.200112.8S21 T25S21-Q23 PolarHBondContact O-N 3Å; Q23-T25 PolarHBondContact O-N 3.36Å
24S70.7Confident84.4Confident50 Ų5065.6 Ų65.635%0.3534%0.342SS..  trans-66.7132.1-176.2-1760000112.4S21 P22 L26S21-S24 VanDerWaalsContact O-CB 3.27Å; S21-S24 WeakPolarHBondContact O-CB 3.21Å; S21-S24 PolarHBondContact O-N 3.4Å; P22-S24 VanDerWaalsContact C-N 3.31Å; S24-L26 PolarHBondContact O-N 3.49Å; S24-L26 WeakPolarHBondContact OG-CB 3.45Å; S24-L26 PolarHBondContact OG-N 3.31Å; S24-L26 VanDerWaalsContact OG-N 3.11Å
25T84.3Confident84.4Confident95 Ų9568.4 Ų68.458%0.58335%0.352SS*.THydrogen-bonded Turntrans-65.5-12.6168.853.50000112.4Q23 A27 S28 Q29Q23-T25 PolarHBondContact O-N 3.36Å; T25-A27 VanDerWaalsContact C-N 3.29Å; T25-A27 PolarHBondContact O-N 3.02Å; T25-S28 WeakPolarHBondContact O-CA 3.38Å; T25-S28 WeakPolarHBondContact O-CB 3.43Å; T25-S28 PolarHBondContact O-N 3.37Å; T25-Q29 PolarHBondContact O-N 2.71Å
26L89.4Confident84.5Confident63 Ų6365.7 Ų65.733%0.3335%0.345SS..Hα-helixtrans-55.3-42.1179.9-176.566000112.2L17 L20 S24 S28 Q29 V30L17-L26 HydrophobicContact CD2-CB 4.46Å; L17-L26 HydrophobicContact CD2-CD2 3.89Å; L17-L26 HydrophobicContact CD2-CG 3.99Å; L20-L26 HydrophobicContact CD1-CD2 3.71Å; S24-L26 PolarHBondContact O-N 3.49Å; S24-L26 WeakPolarHBondContact OG-CB 3.45Å; S24-L26 PolarHBondContact OG-N 3.31Å; S24-L26 VanDerWaalsContact OG-N 3.11Å; L26-S28 VanDerWaalsContact C-N 3.26Å; L26-S28 PolarHBondContact O-N 3.07Å; L26-Q29 PolarHBondContact O-N 2.94Å; L26-V30 HydrophobicContact CD1-CG2 4.11Å; L26-V30 HydrophobicContact CG-CG2 4.24Å; L26-V30 VanDerWaalsContact O-CG2 3.3Å; L26-V30 WeakPolarHBondContact O-CG2 3.33Å; L26-V30 PolarHBondContact O-N 3.43Å
27A89.4Confident84.7Confident7 Ų762.1 Ų62.16%0.05833%0.331CS..Hα-helixtrans-60.5-38.4178.100000111.6L17 T25 D31 I69L17-A27 HydrophobicContact CD1-CB 4.14Å; L17-A27 HydrophobicContact CD2-CB 4.25Å; T25-A27 VanDerWaalsContact C-N 3.29Å; T25-A27 PolarHBondContact O-N 3.02Å; A27-D31 VanDerWaalsContact O-CB 3.22Å; A27-D31 WeakPolarHBondContact O-CB 3.33Å; A27-D31 PolarHBondContact O-N 3.49Å; A27-I69 HydrophobicContact CB-CB 4.45Å
28S89.2Confident84.9Confident45 Ų4561.4 Ų61.432%0.31533%0.328SS..Hα-helixtrans-69.7-40.1175.8-59.90000112.5T25 L26 D31 Q32 I69T25-S28 WeakPolarHBondContact O-CA 3.38Å; T25-S28 WeakPolarHBondContact O-CB 3.43Å; T25-S28 PolarHBondContact O-N 3.37Å; L26-S28 VanDerWaalsContact C-N 3.26Å; L26-S28 PolarHBondContact O-N 3.07Å; S28-D31 PolarHBondContact O-N 3.31Å; S28-Q32 WeakPolarHBondContact O-CB 3.34Å; S28-Q32 PolarHBondContact O-N 3.43Å; S28-I69 WeakPolarHBondContact OG-CD1 3.47Å
29Q92Very high85.2Confident104 Ų10462.1 Ų62.149%0.48633%0.328SS..Hα-helixtrans-65.4-47.5178.2-69.6174.8-6.800111.2T25 L26 D31 Q32 I33T25-Q29 PolarHBondContact O-N 2.71Å; L26-Q29 PolarHBondContact O-N 2.94Å; Q29-D31 VanDerWaalsContact C-N 3.34Å; Q29-D31 PolarHBondContact O-N 2.92Å; Q29-Q32 WeakPolarHBondContact O-CB 3.4Å; Q29-Q32 PolarHBondContact O-N 2.96Å; Q29-I33 WeakPolarHBondContact O-CG1 3.45Å; Q29-I33 PolarHBondContact O-N 2.85Å
30V92.1Very high85.8Confident35 Ų3562.4 Ų62.421%0.21233%0.329CS..Hα-helixtrans-62.2-43.2175.9177.50000110.5L26 Q32 I33 I34 L68L26-V30 HydrophobicContact CD1-CG2 4.11Å; L26-V30 HydrophobicContact CG-CG2 4.24Å; L26-V30 VanDerWaalsContact O-CG2 3.3Å; L26-V30 WeakPolarHBondContact O-CG2 3.33Å; L26-V30 PolarHBondContact O-N 3.43Å; V30-Q32 VanDerWaalsContact C-N 3.31Å; V30-Q32 PolarHBondContact O-N 3.07Å; V30-I33 PolarHBondContact O-N 2.94Å; V30-I34 HydrophobicContact CG1-CD1 3.98Å; V30-I34 HydrophobicContact CG1-CG1 4.46Å; V30-I34 WeakPolarHBondContact O-CG1 3.49Å; V30-I34 PolarHBondContact O-N 3.35Å; V30-L68 HydrophobicContact CB-CD1 4.1Å; V30-L68 HydrophobicContact CG1-CD1 3.56Å
31D91.6Very high86.6Confident3 Ų360.3 Ų60.32%0.01632%0.319CS..Hα-helixtrans-61.3-40.4176.3-162.188000111.3A27 S28 Q29 I34 R35 H55 L68A27-D31 VanDerWaalsContact O-CB 3.22Å; A27-D31 WeakPolarHBondContact O-CB 3.33Å; A27-D31 PolarHBondContact O-N 3.49Å; S28-D31 PolarHBondContact O-N 3.31Å; Q29-D31 VanDerWaalsContact C-N 3.34Å; Q29-D31 PolarHBondContact O-N 2.92Å; D31-I34 PolarHBondContact O-N 2.85Å; D31-R35 WeakPolarHBondContact O-CB 3.4Å; D31-R35 VanDerWaalsContact O-CG 3.25Å; D31-R35 WeakPolarHBondContact O-CG 3.28Å; D31-R35 PolarHBondContact O-N 3.2Å; D31-R35 IonicContact OD2-CZ 2.85Å; D31-R35 IonicContact OD2-NE 2.62Å; D31-R35 IonicContact OD2-NH1 3.73Å; D31-R35 PolarHBondContact OD2-NH1 2.79Å; D31-H55 IonicContact OD1-CE1 3.18Å; D31-H55 IonicContact OD2-CE1 2.7Å; D31-H55 PolarHBondContact OD2-CE1 2.86Å; D31-H55 VanDerWaalsContact OD2-CE1 3.27Å; D31-H55 IonicContact OD2-NE2 3.61Å; D31-H55 PolarHBondContact OD2-NE2 3.21Å; D31-L68 HydrophobicContact CB-CB 4.19Å; D31-L68 HydrophobicContact CB-CD1 4.4Å; D31-L68 HydrophobicContact CB-CG 4.42Å; D31-L68 PolarHBondContact OD1-N 3.44Å
32Q91.5Very high87.6Confident98 Ų9856.7 Ų56.746%0.45829%0.293SS..Hα-helixtrans-60.7-45.3174.6179172.7-18.900112.7S28 Q29 V30 R35 Q36S28-Q32 WeakPolarHBondContact O-CB 3.34Å; S28-Q32 PolarHBondContact O-N 3.43Å; Q29-Q32 WeakPolarHBondContact O-CB 3.4Å; Q29-Q32 PolarHBondContact O-N 2.96Å; V30-Q32 VanDerWaalsContact C-N 3.31Å; V30-Q32 PolarHBondContact O-N 3.07Å; Q32-R35 PolarHBondContact O-N 3.15Å; Q32-Q36 WeakPolarHBondContact O-CG 3.47Å; Q32-Q36 PolarHBondContact O-N 3.06Å
33I92.7Very high88.9Confident100 Ų10061.8 Ų61.851%0.51331%0.314SS..Hα-helixtrans-60.8-49.6176.6-66.3165.7000109.9Q29 V30 R35 Q36 T37Q29-I33 WeakPolarHBondContact O-CG1 3.45Å; Q29-I33 PolarHBondContact O-N 2.85Å; V30-I33 PolarHBondContact O-N 2.94Å; I33-R35 VanDerWaalsContact C-N 3.31Å; I33-R35 PolarHBondContact O-N 2.76Å; I33-Q36 WeakPolarHBondContact O-CB 3.29Å; I33-Q36 PolarHBondContact O-N 3.22Å; I33-Q36 VanDerWaalsContact O-N 3.12Å; I33-T37 PolarHBondContact O-N 2.86Å; I33-T37 PolarHBondContact O-OG1 3.23Å; I33-T37 VanDerWaalsContact O-OG1 3.05Å
34I92.4Very high89.9Confident13 Ų1357 Ų577%0.06729%0.292CS..Hα-helixtrans-57.6-46.1178.5-69.3171.4000110.7I5 L9 I10 V30 D31 Q36 T37 V38 L68I5-I34 HydrophobicContact CG2-CG2 3.92Å; L9-I34 HydrophobicContact CD2-CG1 4.43Å; I10-I34 HydrophobicContact CG1-CD1 4.29Å; V30-I34 HydrophobicContact CG1-CD1 3.98Å; V30-I34 HydrophobicContact CG1-CG1 4.46Å; V30-I34 WeakPolarHBondContact O-CG1 3.49Å; V30-I34 PolarHBondContact O-N 3.35Å; D31-I34 PolarHBondContact O-N 2.85Å; I34-Q36 VanDerWaalsContact C-N 3.35Å; I34-Q36 PolarHBondContact O-N 3.34Å; I34-T37 PolarHBondContact O-N 3.49Å; I34-V38 HydrophobicContact CG2-CG2 4.31Å; I34-V38 WeakPolarHBondContact O-CB 3.5Å; I34-V38 VanDerWaalsContact O-CG2 3.24Å; I34-V38 WeakPolarHBondContact O-CG2 3.3Å; I34-V38 PolarHBondContact O-N 3.05Å; I34-L68 HydrophobicContact CD1-CD1 3.64Å; I34-L68 HydrophobicContact CD1-CG 4.44Å
35R91.7Very high90.4Very high72 Ų7256.5 Ų56.527%0.27229%0.288SS..Hα-helixtrans-58.5-47.7177.3-71.2-175.4-48.1-120.92.5110.7D31 Q32 I33 V38 K39 L54D31-R35 WeakPolarHBondContact O-CB 3.4Å; D31-R35 VanDerWaalsContact O-CG 3.25Å; D31-R35 WeakPolarHBondContact O-CG 3.28Å; D31-R35 PolarHBondContact O-N 3.2Å; D31-R35 IonicContact OD2-CZ 2.85Å; D31-R35 IonicContact OD2-NE 2.62Å; D31-R35 IonicContact OD2-NH1 3.73Å; D31-R35 PolarHBondContact OD2-NH1 2.79Å; Q32-R35 PolarHBondContact O-N 3.15Å; I33-R35 VanDerWaalsContact C-N 3.31Å; I33-R35 PolarHBondContact O-N 2.76Å; R35-V38 PolarHBondContact O-N 3.1Å; R35-K39 WeakPolarHBondContact O-CG 3.44Å; R35-K39 PolarHBondContact O-N 2.78Å; R35-L54 HydrophobicContact CB-CD1 3.98Å; R35-L54 HydrophobicContact CG-CD1 3.77Å
36Q91.6Very high89.7Confident98 Ų9856.2 Ų56.246%0.45830%0.295SS..Hα-helixtrans-59.5-48.1178.1-74.3176-15.900112.1Q32 I33 I34 V38 K39 Q40Q32-Q36 WeakPolarHBondContact O-CG 3.47Å; Q32-Q36 PolarHBondContact O-N 3.06Å; I33-Q36 WeakPolarHBondContact O-CB 3.29Å; I33-Q36 PolarHBondContact O-N 3.22Å; I33-Q36 VanDerWaalsContact O-N 3.12Å; I34-Q36 VanDerWaalsContact C-N 3.35Å; I34-Q36 PolarHBondContact O-N 3.34Å; Q36-V38 VanDerWaalsContact C-N 3.3Å; Q36-V38 PolarHBondContact O-N 2.88Å; Q36-K39 WeakPolarHBondContact O-CB 3.24Å; Q36-K39 PolarHBondContact O-N 3.15Å; Q36-K39 VanDerWaalsContact O-N 3.13Å; Q36-Q40 WeakPolarHBondContact O-CG 3.47Å; Q36-Q40 PolarHBondContact O-N 3.03Å
37T92.6Very high88.7Confident51 Ų5159.5 Ų59.531%0.31332%0.318SS..Hα-helixtrans-60.2-39.8176.4-55.40000111.9I5 I33 I34 Q40 N41I5-T37 HydrophobicContact CD1-CG2 4.15Å; I33-T37 PolarHBondContact O-N 2.86Å; I33-T37 PolarHBondContact O-OG1 3.23Å; I33-T37 VanDerWaalsContact O-OG1 3.05Å; I34-T37 PolarHBondContact O-N 3.49Å; T37-Q40 PolarHBondContact O-N 2.83Å; T37-N41 WeakPolarHBondContact O-CB 3.39Å; T37-N41 VanDerWaalsContact O-CG 3.3Å; T37-N41 PolarHBondContact O-N 3.19Å; T37-N41 PolarHBondContact O-ND2 3.45Å
38V92.4Very high87.2Confident0 Ų059.5 Ų59.50%032%0.318CS..Hα-helixtrans-66.9-41175.4171.30000111I5 I34 R35 Q36 Q40 N41 L42 L54 L63 L65I5-V38 HydrophobicContact CD1-CG2 3.89Å; I5-V38 HydrophobicContact CG2-CG2 4.45Å; I34-V38 HydrophobicContact CG2-CG2 4.31Å; I34-V38 WeakPolarHBondContact O-CB 3.5Å; I34-V38 VanDerWaalsContact O-CG2 3.24Å; I34-V38 WeakPolarHBondContact O-CG2 3.3Å; I34-V38 PolarHBondContact O-N 3.05Å; R35-V38 PolarHBondContact O-N 3.1Å; Q36-V38 VanDerWaalsContact C-N 3.3Å; Q36-V38 PolarHBondContact O-N 2.88Å; V38-Q40 VanDerWaalsContact C-N 3.34Å; V38-Q40 PolarHBondContact O-N 3.38Å; V38-N41 PolarHBondContact O-N 3.46Å; V38-L42 HydrophobicContact CG1-CD1 3.74Å; V38-L42 HydrophobicContact CG1-CG 4.45Å; V38-L42 WeakPolarHBondContact O-CB 3.31Å; V38-L42 WeakPolarHBondContact O-CG 3.45Å; V38-L42 PolarHBondContact O-N 3.42Å; V38-L54 HydrophobicContact CG1-CD2 3.89Å; V38-L63 HydrophobicContact CG1-CD2 3.86Å; V38-L65 HydrophobicContact CB-CD1 4.39Å; V38-L65 HydrophobicContact CG1-CD1 4.08Å; V38-L65 HydrophobicContact CG2-CD1 3.77Å
39K90.9Very high86Confident40 Ų4057.9 Ų57.917%0.17431%0.306CS..Hα-helixtrans-58.7-47.3175.6-46.6-146.8174.3-177.50111.2R35 Q36 L42 H43 L44 A46 I49R35-K39 WeakPolarHBondContact O-CG 3.44Å; R35-K39 PolarHBondContact O-N 2.78Å; Q36-K39 WeakPolarHBondContact O-CB 3.24Å; Q36-K39 PolarHBondContact O-N 3.15Å; Q36-K39 VanDerWaalsContact O-N 3.13Å; K39-L42 CarbonylContact O-C 3.37Å; K39-L42 PolarHBondContact O-N 3.02Å; K39-H43 PolarHBondContact O-N 2.87Å; K39-H43 VanDerWaalsContact O-N 3.14Å; K39-L44 PolarHBondContact O-N 3.46Å; K39-A46 PolarHBondContact NZ-O 3.44Å; K39-A46 VanDerWaalsContact NZ-O 3.11Å; K39-I49 HydrophobicContact CB-CD1 3.71Å; K39-I49 HydrophobicContact CD-CB 4.1Å; K39-I49 HydrophobicContact CD-CD1 3.48Å; K39-I49 VanDerWaalsContact CD-CD1 3.48Å; K39-I49 HydrophobicContact CD-CG1 4.46Å; K39-I49 HydrophobicContact CG-CD1 3.42Å; K39-I49 VanDerWaalsContact CG-CD1 3.42Å; K39-I49 PolarHBondContact NZ-O 3.5Å
40Q92Very high85Confident138 Ų13854.3 Ų54.365%0.64529%0.291SS*.Hα-helixtrans-61.9-48179.7-71.4171-11.100111.5Q36 T37 V38 L42 H43Q36-Q40 WeakPolarHBondContact O-CG 3.47Å; Q36-Q40 PolarHBondContact O-N 3.03Å; T37-Q40 PolarHBondContact O-N 2.83Å; V38-Q40 VanDerWaalsContact C-N 3.34Å; V38-Q40 PolarHBondContact O-N 3.38Å; Q40-L42 PolarHBondContact O-N 3.08Å; Q40-H43 PolarHBondContact O-N 3.42Å
41N91.9Very high84.5Confident38 Ų3853.8 Ų53.820%0.20329%0.293CS..Hα-helixtrans-63.9-24.9178.3-77-40.6000113.6K1 T37 V38K1-N41 WeakPolarHBondContact CD-OD1 3.49Å; T37-N41 WeakPolarHBondContact O-CB 3.39Å; T37-N41 VanDerWaalsContact O-CG 3.3Å; T37-N41 PolarHBondContact O-N 3.19Å; T37-N41 PolarHBondContact O-ND2 3.45Å; V38-N41 PolarHBondContact O-N 3.46Å
42L91.1Very high84.4Confident1 Ų154.4 Ų54.41%0.00530%0.297CS..THydrogen-bonded Turntrans-93.41176.5-71173.6000113.3I2 V38 K39 Q40 L44 L63 F168 I169 I172I2-L42 HydrophobicContact CD1-CD1 3.98Å; I2-L42 HydrophobicContact CD1-CD2 3.25Å; I2-L42 HydrophobicContact CD1-CG 3.51Å; V38-L42 HydrophobicContact CG1-CD1 3.74Å; V38-L42 HydrophobicContact CG1-CG 4.45Å; V38-L42 WeakPolarHBondContact O-CB 3.31Å; V38-L42 WeakPolarHBondContact O-CG 3.45Å; V38-L42 PolarHBondContact O-N 3.42Å; K39-L42 CarbonylContact O-C 3.37Å; K39-L42 PolarHBondContact O-N 3.02Å; Q40-L42 PolarHBondContact O-N 3.08Å; L42-L44 HydrophobicContact CB-CB 4.45Å; L42-L44 HydrophobicContact CB-CD1 3.43Å; L42-L44 VanDerWaalsContact CB-CD1 3.43Å; L42-L44 HydrophobicContact CB-CG 3.62Å; L42-L44 HydrophobicContact CD1-CD1 3.6Å; L42-L44 HydrophobicContact CG-CD1 4.13Å; L42-L44 PolarHBondContact O-N 3.24Å; L42-L63 HydrophobicContact CD1-CD2 4.17Å; L42-F168 HydrophobicContact CD2-CD1 4.15Å; L42-F168 HydrophobicContact CD2-CE1 3.9Å; L42-I169 HydrophobicContact CD2-CG1 4.24Å; L42-I169 WeakPolarHBondContact O-CG2 3.31Å; L42-I172 HydrophobicContact CD1-CG2 4.32Å; L42-I172 HydrophobicContact CD2-CG1 4.28Å
43H90.6Very high84.4Confident132 Ų13249.9 Ų49.961%0.61128%0.276SS*.THydrogen-bonded Turntrans48.742.1-172.6-54.5-81.2000112.1K39 Q40 Q173K39-H43 PolarHBondContact O-N 2.87Å; K39-H43 VanDerWaalsContact O-N 3.14Å; Q40-H43 PolarHBondContact O-N 3.42Å; H43-Q173 PolarHBondContact O-NE2 3.37Å; H43-Q173 VanDerWaalsContact O-NE2 3.1Å
44L87.9Confident84.4Confident14 Ų1445.2 Ų45.27%0.07325%0.252CS..  trans-92.1142.9179-69.2169.7000109.6K39 L42 I49 I172 Q173 T178K39-L44 PolarHBondContact O-N 3.46Å; L42-L44 HydrophobicContact CB-CB 4.45Å; L42-L44 HydrophobicContact CB-CD1 3.43Å; L42-L44 VanDerWaalsContact CB-CD1 3.43Å; L42-L44 HydrophobicContact CB-CG 3.62Å; L42-L44 HydrophobicContact CD1-CD1 3.6Å; L42-L44 HydrophobicContact CG-CD1 4.13Å; L42-L44 PolarHBondContact O-N 3.24Å; L44-I49 HydrophobicContact CB-CD1 3.42Å; L44-I49 VanDerWaalsContact CB-CD1 3.42Å; L44-I49 HydrophobicContact CB-CG1 4.1Å; L44-I49 HydrophobicContact CD1-CD1 3.32Å; L44-I49 HydrophobicContact CD1-CG1 3.63Å; L44-I49 HydrophobicContact CG-CD1 3.93Å; L44-I49 HydrophobicContact CG-CG1 4.37Å; L44-I172 HydrophobicContact CD1-CG2 3.91Å; L44-Q173 HydrophobicContact CD2-CG 3.77Å; L44-T178 HydrophobicContact CD2-CG2 4.36Å; L44-T178 WeakPolarHBondContact CD2-OG1 3.41Å
45P80.9Confident84.4Confident39 Ų3945.7 Ų45.725%0.25325%0.254SS..  trans-56.5142.7177.4-15.723.9000110.7T47 A48P45-T47 PolarHBondContact O-N 3.11Å; P45-A48 HydrophobicContact CB-CB 3.69Å; P45-A48 HydrophobicContact CG-CB 3.6Å; P45-A48 CarbonylContact O-C 3.6Å; P45-A48 PolarHBondContact O-N 2.95Å; P45-A48 VanDerWaalsContact O-O 3.09Å
46A70Confident84.4Confident89 Ų8942.2 Ų42.274%0.73624%0.241SC*.THydrogen-bonded Turntrans-56.1-39179.900000112.1K39K39-A46 PolarHBondContact NZ-O 3.44Å; K39-A46 VanDerWaalsContact NZ-O 3.11Å
47T68Low84.4Confident132 Ų13239.9 Ų39.981%0.8123%0.234SC*.THydrogen-bonded Turntrans-73.7-24175.755.90000113.3P45P45-T47 PolarHBondContact O-N 3.11Å
48A59.1Low84.3Confident8 Ų838.5 Ų38.57%0.06623%0.225CC..  trans-108.984.8-173.600000110.9P45 T178P45-A48 HydrophobicContact CB-CB 3.69Å; P45-A48 HydrophobicContact CG-CB 3.6Å; P45-A48 CarbonylContact O-C 3.6Å; P45-A48 PolarHBondContact O-N 2.95Å; P45-A48 VanDerWaalsContact O-O 3.09Å; A48-T178 HydrophobicContact CB-CG2 3.52Å
49I63.2Low84.1Confident10 Ų1045.5 Ų45.55%0.05126%0.258CS..  trans-167.6108.9145.7-84.2140.5000104K39 L44 G51 L54K39-I49 HydrophobicContact CB-CD1 3.71Å; K39-I49 HydrophobicContact CD-CB 4.1Å; K39-I49 HydrophobicContact CD-CD1 3.48Å; K39-I49 VanDerWaalsContact CD-CD1 3.48Å; K39-I49 HydrophobicContact CD-CG1 4.46Å; K39-I49 HydrophobicContact CG-CD1 3.42Å; K39-I49 VanDerWaalsContact CG-CD1 3.42Å; K39-I49 PolarHBondContact NZ-O 3.5Å; L44-I49 HydrophobicContact CB-CD1 3.42Å; L44-I49 VanDerWaalsContact CB-CD1 3.42Å; L44-I49 HydrophobicContact CB-CG1 4.1Å; L44-I49 HydrophobicContact CD1-CD1 3.32Å; L44-I49 HydrophobicContact CD1-CG1 3.63Å; L44-I49 HydrophobicContact CG-CD1 3.93Å; L44-I49 HydrophobicContact CG-CG1 4.37Å; I49-G51 PolarHBondContact O-N 3.28Å; I49-L54 HydrophobicContact CG2-CD1 3.65Å; I49-L54 HydrophobicContact CG2-CD2 4.03Å; I49-L54 HydrophobicContact CG2-CG 3.5Å
50T71.3Confident84.1Confident30 Ų3045.9 Ų45.918%0.18426%0.26CS..  trans-59.1110.3164.2-54.30000106.6P52 F53 L136 T139T50-P52 HydrophobicContact CG2-CB 4Å; T50-P52 HydrophobicContact CG2-CG 3.68Å; T50-F53 PolarHBondContact O-N 3Å; T50-L136 HydrophobicContact CG2-CD1 4.22Å; T50-T139 HydrophobicContact CG2-CG2 3.68Å
51G81.7Confident83.9Confident23 Ų2339.3 Ų39.324%0.23723%0.23CC..Hα-helixtrans-37.6-39178.200000114.8I49 F53 L54 H55I49-G51 PolarHBondContact O-N 3.28Å; G51-F53 VanDerWaalsContact C-N 3.34Å; G51-F53 PolarHBondContact O-N 3.32Å; G51-L54 PolarHBondContact O-N 2.84Å; G51-L54 VanDerWaalsContact O-N 3.17Å; G51-H55 PolarHBondContact O-CD2 3.03Å; G51-H55 PolarHBondContact O-N 3.45Å
52P89.4Confident83.9Confident16 Ų1637.5 Ų37.510%0.10422%0.22CC..Hα-helixtrans-46.9-41.3168.5-33.532.9000117.6T50 L54 H55 L56 L132 Q135 L136T50-P52 HydrophobicContact CG2-CB 4Å; T50-P52 HydrophobicContact CG2-CG 3.68Å; P52-L54 VanDerWaalsContact C-N 3.33Å; P52-L54 PolarHBondContact O-N 3.46Å; P52-H55 PolarHBondContact O-N 3.48Å; P52-L56 WeakPolarHBondContact O-CB 3.4Å; P52-L56 PolarHBondContact O-N 3.29Å; P52-L132 HydrophobicContact CB-CB 4.3Å; P52-L132 HydrophobicContact CB-CD2 4.18Å; P52-L132 WeakPolarHBondContact CB-O 3Å; P52-L132 HydrophobicContact CG-CD2 4.03Å; P52-Q135 HydrophobicContact CG-CB 3.93Å; P52-L136 HydrophobicContact CB-CB 3.95Å
53F91.4Very high83.9Confident4 Ų437.6 Ų37.62%0.01822%0.22CC..Hα-helixtrans-61.5-40.3179.1174.1-105.3000112.5T50 G51 H55 G61 G62 L63 L136 L145 I172 T176T50-F53 PolarHBondContact O-N 3Å; G51-F53 VanDerWaalsContact C-N 3.34Å; G51-F53 PolarHBondContact O-N 3.32Å; F53-H55 VanDerWaalsContact C-N 3.34Å; F53-G61 WeakPolarHBondContact CE2-O 3.45Å; F53-G62 CarbonylContact O-C 3.58Å; F53-G62 WeakPolarHBondContact O-CA 3.45Å; F53-L63 HydrophobicContact CE1-CB 4.33Å; F53-L63 PolarHBondContact O-N 3.25Å; F53-L136 HydrophobicContact CB-CD1 3.83Å; F53-L136 HydrophobicContact CB-CD2 4.35Å; F53-L136 HydrophobicContact CD2-CD2 4.4Å; F53-L145 HydrophobicContact CD2-CD1 3.56Å; F53-L145 HydrophobicContact CE2-CD1 3.86Å; F53-I172 HydrophobicContact CE1-CG2 3.91Å; F53-I172 HydrophobicContact CZ-CD1 4.24Å; F53-I172 HydrophobicContact CZ-CG2 4.16Å; F53-T176 HydrophobicContact CD1-CG2 3.81Å; F53-T176 HydrophobicContact CD2-CG2 3.96Å; F53-T176 HydrophobicContact CE1-CG2 3.65Å; F53-T176 HydrophobicContact CE2-CG2 3.8Å; F53-T176 HydrophobicContact CG-CG2 3.96Å; F53-T176 HydrophobicContact CZ-CG2 3.64Å
54L91.6Very high83.9Confident1 Ų131.9 Ų31.91%0.00520%0.198CC..Hα-helixtrans-67.4-39.6179.1-63.1179.8000111R35 V38 I49 G51 P52 L63 G64 L65R35-L54 HydrophobicContact CB-CD1 3.98Å; R35-L54 HydrophobicContact CG-CD1 3.77Å; V38-L54 HydrophobicContact CG1-CD2 3.89Å; I49-L54 HydrophobicContact CG2-CD1 3.65Å; I49-L54 HydrophobicContact CG2-CD2 4.03Å; I49-L54 HydrophobicContact CG2-CG 3.5Å; G51-L54 PolarHBondContact O-N 2.84Å; G51-L54 VanDerWaalsContact O-N 3.17Å; P52-L54 VanDerWaalsContact C-N 3.33Å; P52-L54 PolarHBondContact O-N 3.46Å; L54-L63 HydrophobicContact CD2-CB 4.39Å; L54-L63 HydrophobicContact CD2-CD2 3.71Å; L54-G64 PolarHBondContact O-N 2.97Å; L54-L65 HydrophobicContact CB-CD1 4.43Å; L54-L65 WeakPolarHBondContact O-CB 3.49Å; L54-L65 PolarHBondContact O-N 3.38Å
55H92.6Very high84.1Confident23 Ų2331.4 Ų31.411%0.10620%0.195CC..Hα-helixtrans-86.8-23.6-173.4-61.3-52.6000115.4D31 G51 P52 F53 L65 S67 L132D31-H55 IonicContact OD1-CE1 3.18Å; D31-H55 IonicContact OD2-CE1 2.7Å; D31-H55 PolarHBondContact OD2-CE1 2.86Å; D31-H55 VanDerWaalsContact OD2-CE1 3.27Å; D31-H55 IonicContact OD2-NE2 3.61Å; D31-H55 PolarHBondContact OD2-NE2 3.21Å; G51-H55 PolarHBondContact O-CD2 3.03Å; G51-H55 PolarHBondContact O-N 3.45Å; P52-H55 PolarHBondContact O-N 3.48Å; F53-H55 VanDerWaalsContact C-N 3.34Å; H55-L65 VanDerWaalsContact CA-O 3.22Å; H55-L65 WeakPolarHBondContact CA-O 3.3Å; H55-L65 PolarHBondContact ND1-O 3.42Å; H55-S67 WeakPolarHBondContact ND1-CA 3.2Å; H55-S67 PolarHBondContact ND1-N 3.41Å; H55-L132 HydrophobicContact CB-CD1 3.92Å
56L91.8Very high84.6Confident0 Ų031.5 Ų31.50%020%0.196CC..SBendtrans-64.1135.5179-172.672.3000110P52 H60 G62 G64 E133 L136P52-L56 WeakPolarHBondContact O-CB 3.4Å; P52-L56 PolarHBondContact O-N 3.29Å; L56-H60 HydrophobicContact CD1-CB 4.05Å; L56-H60 HydrophobicContact CD2-CB 3.82Å; L56-H60 VanDerWaalsContact CD2-O 3.28Å; L56-H60 WeakPolarHBondContact CD2-O 3.21Å; L56-H60 HydrophobicContact CG-CB 3.82Å; L56-G62 CarbonylContact O-C 3.57Å; L56-G62 VanDerWaalsContact O-CA 3.28Å; L56-G62 WeakPolarHBondContact O-CA 3.42Å; L56-G64 WeakPolarHBondContact O-CA 3.41Å; L56-G64 PolarHBondContact O-N 3.03Å; L56-E133 HydrophobicContact CD1-CB 3.9Å; L56-L136 HydrophobicContact CD2-CD2 3.72Å
57P91.2Very high85.6Confident48 Ų4828 Ų2831%0.31217%0.165SC..  trans-59.4153179.8-22.132000112.8Q59 H60 G62P57-Q59 PolarHBondContact O-N 2.94Å; P57-H60 PolarHBondContact O-N 2.92Å; P57-G62 PolarHBondContact O-N 2.98Å
58T91.1Very high86.7Confident23 Ų2321.7 Ų21.714%0.14113%0.127CC..G310 helixtrans-60.6-29.8-179.9-56.90000113.5R6 H60 G61 G62 N155 L158R6-T58 PolarHBondContact NH2-OG1 3.31Å; T58-H60 PolarHBondContact O-N 2.97Å; T58-G61 PolarHBondContact O-N 2.6Å; T58-G61 VanDerWaalsContact O-N 3.11Å; T58-G62 VanDerWaalsContact CA-O 3.25Å; T58-G62 WeakPolarHBondContact CA-O 3.5Å; T58-G62 PolarHBondContact OG1-O 3.36Å; T58-N155 HydrophobicContact CG2-CB 4.48Å; T58-N155 VanDerWaalsContact O-CB 3.27Å; T58-N155 WeakPolarHBondContact O-CB 3.48Å; T58-N155 PolarHBondContact O-ND2 2.92Å; T58-L158 HydrophobicContact CG2-CB 3.58Å; T58-L158 HydrophobicContact CG2-CD1 3.96Å; T58-L158 HydrophobicContact CG2-CG 4.4Å
59Q89.4Confident88.1Confident146 Ų14622.9 Ų22.968%0.68213%0.132SC*.G310 helixtrans-61.7-28.8175.2-64.3172.5-11.700112.9P57 S150 N155P57-Q59 PolarHBondContact O-N 2.94Å; Q59-S150 WeakPolarHBondContact O-CA 3.28Å; Q59-S150 PolarHBondContact O-N 2.87Å; Q59-N155 PolarHBondContact O-ND2 2.99Å; Q59-N155 VanDerWaalsContact O-ND2 3.14Å
60H89.5Confident89.4Confident48 Ų4824 Ų2422%0.22214%0.138CC..G310 helixtrans-100.717.1178.8-55.8-77.6000112.2L56 P57 T58L56-H60 HydrophobicContact CD1-CB 4.05Å; L56-H60 HydrophobicContact CD2-CB 3.82Å; L56-H60 VanDerWaalsContact CD2-O 3.28Å; L56-H60 WeakPolarHBondContact CD2-O 3.21Å; L56-H60 HydrophobicContact CG-CB 3.82Å; P57-H60 PolarHBondContact O-N 2.92Å; T58-H60 PolarHBondContact O-N 2.97Å
61G88.8Confident90.4Very high0 Ų024.5 Ų24.50%014%0.141CC..THydrogen-bonded Turntrans83.75.6177.300000115.9F53 T58 N155F53-G61 WeakPolarHBondContact CE2-O 3.45Å; T58-G61 PolarHBondContact O-N 2.6Å; T58-G61 VanDerWaalsContact O-N 3.11Å; G61-N155 PolarHBondContact N-ND2 3.23Å
62G91Very high90.8Very high0 Ų023.7 Ų23.70%013%0.132CC..SBendtrans-89.3174.4174.600000114.5F53 L56 P57 T58 G64 L158F53-G62 CarbonylContact O-C 3.58Å; F53-G62 WeakPolarHBondContact O-CA 3.45Å; L56-G62 CarbonylContact O-C 3.57Å; L56-G62 VanDerWaalsContact O-CA 3.28Å; L56-G62 WeakPolarHBondContact O-CA 3.42Å; P57-G62 PolarHBondContact O-N 2.98Å; T58-G62 VanDerWaalsContact CA-O 3.25Å; T58-G62 WeakPolarHBondContact CA-O 3.5Å; T58-G62 PolarHBondContact OG1-O 3.36Å; G62-G64 VanDerWaalsContact C-N 3.27Å; G62-G64 PolarHBondContact O-N 3.4Å; G62-L158 WeakPolarHBondContact O-CD1 3.36Å
63L91.2Very high90.9Very high3 Ų325.1 Ų25.12%0.01614%0.135CC..  trans-75.9-18.4178.6-159.166.6000112.6I2 R6 V38 L42 F53 L54 L65 F168 I172I2-L63 HydrophobicContact CG2-CD2 4.4Å; R6-L63 PolarHBondContact NH1-O 3.01Å; R6-L63 PolarHBondContact NH2-O 3.17Å; V38-L63 HydrophobicContact CG1-CD2 3.86Å; L42-L63 HydrophobicContact CD1-CD2 4.17Å; F53-L63 HydrophobicContact CE1-CB 4.33Å; F53-L63 PolarHBondContact O-N 3.25Å; L54-L63 HydrophobicContact CD2-CB 4.39Å; L54-L63 HydrophobicContact CD2-CD2 3.71Å; L63-L65 HydrophobicContact CD2-CD1 3.9Å; L63-L65 HydrophobicContact CD2-CG 4.17Å; L63-L65 HydrophobicContact CG-CG 4.4Å; L63-F168 HydrophobicContact CD1-CZ 4Å; L63-I172 HydrophobicContact CD1-CD1 4.08Å
64G91.2Very high90.9Very high13 Ų1326.2 Ų26.213%0.13414%0.14CC..  trans64.139.717600000114.4R6 L54 L56 G62R6-G64 PolarHBondContact NE-O 3.05Å; R6-G64 VanDerWaalsContact NH2-CA 3.27Å; R6-G64 PolarHBondContact NH2-O 3.15Å; L54-G64 PolarHBondContact O-N 2.97Å; L56-G64 WeakPolarHBondContact O-CA 3.41Å; L56-G64 PolarHBondContact O-N 3.03Å; G62-G64 VanDerWaalsContact C-N 3.27Å; G62-G64 PolarHBondContact O-N 3.4Å
65L92.2Very high90.9Very high3 Ų330.3 Ų30.32%0.01616%0.158CC..  trans-85.3112.2166.3-60.4179.1000109R6 I10 V38 L54 H55 L63 S67R6-L65 HydrophobicContact CB-CD2 4.11Å; R6-L65 HydrophobicContact CG-CD2 4.17Å; I10-L65 HydrophobicContact CD1-CB 4.22Å; I10-L65 HydrophobicContact CD1-CD2 3.84Å; V38-L65 HydrophobicContact CB-CD1 4.39Å; V38-L65 HydrophobicContact CG1-CD1 4.08Å; V38-L65 HydrophobicContact CG2-CD1 3.77Å; L54-L65 HydrophobicContact CB-CD1 4.43Å; L54-L65 WeakPolarHBondContact O-CB 3.49Å; L54-L65 PolarHBondContact O-N 3.38Å; H55-L65 VanDerWaalsContact CA-O 3.22Å; H55-L65 WeakPolarHBondContact CA-O 3.3Å; H55-L65 PolarHBondContact ND1-O 3.42Å; L63-L65 HydrophobicContact CD2-CD1 3.9Å; L63-L65 HydrophobicContact CD2-CG 4.17Å; L63-L65 HydrophobicContact CG-CG 4.4Å; L65-S67 PolarHBondContact O-N 3.21Å
66P91.1Very high90.8Very high42 Ų4229.7 Ų29.727%0.27316%0.156SC..  trans-58134.9-179.524.9-34.3000111.2I10 I14 L68 V71I10-P66 HydrophobicContact CD1-CG 4.47Å; I10-P66 HydrophobicContact CG2-CG 3.39Å; I14-P66 HydrophobicContact CD1-CG 4.13Å; P66-L68 PolarHBondContact O-N 2.74Å; P66-V71 HydrophobicContact CB-CG2 3.7Å
67S90.6Very high90.8Very high14 Ų1429.7 Ų29.710%0.09816%0.156CC..  trans-67.3116170.9175.60000109H55 L65 I69 N70 V71H55-S67 WeakPolarHBondContact ND1-CA 3.2Å; H55-S67 PolarHBondContact ND1-N 3.41Å; L65-S67 PolarHBondContact O-N 3.21Å; S67-I69 VanDerWaalsContact C-N 3.32Å; S67-I69 PolarHBondContact O-N 2.91Å; S67-I69 WeakPolarHBondContact OG-CG2 3.41Å; S67-N70 PolarHBondContact O-N 3.15Å; S67-V71 WeakPolarHBondContact O-CB 3.44Å; S67-V71 WeakPolarHBondContact O-CG2 3.41Å; S67-V71 PolarHBondContact O-N 3.48Å
68L90.6Very high90.9Very high1 Ų133.1 Ų33.11%0.00516%0.163CC..Hα-helixtrans-59.6-46-173.4-67.3-177.2000111I10 C13 I14 L17 V30 D31 I34 P66 N70 V71 T72I10-L68 HydrophobicContact CG2-CD2 4.37Å; C13-L68 HydrophobicContact CB-CD1 4.17Å; C13-L68 HydrophobicContact CB-CD2 4.29Å; I14-L68 HydrophobicContact CD1-CD2 4.31Å; I14-L68 HydrophobicContact CG1-CD2 3.61Å; L17-L68 HydrophobicContact CD1-CB 4.22Å; L17-L68 HydrophobicContact CD1-CD1 3.96Å; V30-L68 HydrophobicContact CB-CD1 4.1Å; V30-L68 HydrophobicContact CG1-CD1 3.56Å; D31-L68 HydrophobicContact CB-CB 4.19Å; D31-L68 HydrophobicContact CB-CD1 4.4Å; D31-L68 HydrophobicContact CB-CG 4.42Å; D31-L68 PolarHBondContact OD1-N 3.44Å; I34-L68 HydrophobicContact CD1-CD1 3.64Å; I34-L68 HydrophobicContact CD1-CG 4.44Å; P66-L68 PolarHBondContact O-N 2.74Å; L68-N70 PolarHBondContact O-N 2.99Å; L68-V71 PolarHBondContact O-N 3.27Å; L68-T72 WeakPolarHBondContact O-CB 3.28Å; L68-T72 WeakPolarHBondContact O-CG2 3.37Å; L68-T72 PolarHBondContact O-N 3.14Å; L68-T72 PolarHBondContact O-OG1 3.24Å
69I89.4Confident90.9Very high32 Ų3235.1 Ų35.116%0.16418%0.178CC..Hα-helixtrans-55.4-46.6177.8179.7159.2000112.7A27 S28 S67 T72 R73A27-I69 HydrophobicContact CB-CB 4.45Å; S28-I69 WeakPolarHBondContact OG-CD1 3.47Å; S67-I69 VanDerWaalsContact C-N 3.32Å; S67-I69 PolarHBondContact O-N 2.91Å; S67-I69 WeakPolarHBondContact OG-CG2 3.41Å; I69-T72 PolarHBondContact O-OG1 3.48Å; I69-T72 VanDerWaalsContact O-OG1 3.12Å; I69-R73 VanDerWaalsContact CD1-CZ 3.45Å; I69-R73 WeakPolarHBondContact O-CB 3.27Å; I69-R73 VanDerWaalsContact O-CD 3.28Å; I69-R73 WeakPolarHBondContact O-CD 3.31Å; I69-R73 WeakPolarHBondContact O-CG 3.3Å; I69-R73 PolarHBondContact O-N 2.79Å
70N90.7Very high91.1Very high35 Ų3529.6 Ų29.619%0.18715%0.152CC..Hα-helixtrans-74.4-38.5-177.6-71.4-27000111.5S67 L68 I74 L128S67-N70 PolarHBondContact O-N 3.15Å; L68-N70 PolarHBondContact O-N 2.99Å; N70-I74 WeakPolarHBondContact O-CB 3.33Å; N70-I74 WeakPolarHBondContact O-CD1 3.27Å; N70-I74 VanDerWaalsContact O-CG1 3.27Å; N70-I74 WeakPolarHBondContact O-CG1 3.49Å; N70-I74 PolarHBondContact O-N 3.33Å; N70-L128 HydrophobicContact CB-CD1 4.13Å
71V91.4Very high91.3Very high39 Ų3927.5 Ų27.524%0.23614%0.142CC..Hα-helixtrans-70.1-40.9-180171.70000111.8I14 P66 S67 L68 K75I14-V71 HydrophobicContact CD1-CG1 3.93Å; I14-V71 HydrophobicContact CG1-CG1 4.18Å; I14-V71 HydrophobicContact CG2-CG1 3.99Å; P66-V71 HydrophobicContact CB-CG2 3.7Å; S67-V71 WeakPolarHBondContact O-CB 3.44Å; S67-V71 WeakPolarHBondContact O-CG2 3.41Å; S67-V71 PolarHBondContact O-N 3.48Å; L68-V71 PolarHBondContact O-N 3.27Å; V71-K75 HydrophobicContact CG1-CD 4.4Å; V71-K75 HydrophobicContact CG1-CG 4.38Å; V71-K75 VanDerWaalsContact O-CB 3.3Å; V71-K75 WeakPolarHBondContact O-CB 3.35Å; V71-K75 WeakPolarHBondContact O-CG 3.44Å; V71-K75 PolarHBondContact O-N 3.05Å
72T90.8Very high91.5Very high7 Ų733.4 Ų33.44%0.04317%0.168CC..Hα-helixtrans-64.6-48.2177.456.90000110.2L17 L68 I69 I74 K75 T76L17-T72 HydrophobicContact CB-CG2 3.42Å; L17-T72 VanDerWaalsContact CB-CG2 3.42Å; L17-T72 HydrophobicContact CD1-CG2 4.17Å; L17-T72 HydrophobicContact CG-CG2 4.45Å; L68-T72 WeakPolarHBondContact O-CB 3.28Å; L68-T72 WeakPolarHBondContact O-CG2 3.37Å; L68-T72 PolarHBondContact O-N 3.14Å; L68-T72 PolarHBondContact O-OG1 3.24Å; I69-T72 PolarHBondContact O-OG1 3.48Å; I69-T72 VanDerWaalsContact O-OG1 3.12Å; T72-I74 PolarHBondContact O-N 2.95Å; T72-K75 PolarHBondContact O-N 3.38Å; T72-K75 VanDerWaalsContact O-N 3.15Å; T72-T76 WeakPolarHBondContact O-CB 3.06Å; T72-T76 PolarHBondContact O-N 2.97Å; T72-T76 PolarHBondContact O-OG1 3.45Å
73R91.1Very high91.6Very high46 Ų4635.4 Ų35.417%0.17418%0.179CC..Hα-helixtrans-54.6-49.8175.8-71.5172.9172171.7-4.8112.7I69 T76 L77 L107 L111I69-R73 VanDerWaalsContact CD1-CZ 3.45Å; I69-R73 WeakPolarHBondContact O-CB 3.27Å; I69-R73 VanDerWaalsContact O-CD 3.28Å; I69-R73 WeakPolarHBondContact O-CD 3.31Å; I69-R73 WeakPolarHBondContact O-CG 3.3Å; I69-R73 PolarHBondContact O-N 2.79Å; R73-T76 PolarHBondContact O-N 2.84Å; R73-L77 PolarHBondContact O-N 3.28Å; R73-L107 HydrophobicContact CB-CD2 3.82Å; R73-L107 HydrophobicContact CG-CD2 3.54Å; R73-L111 HydrophobicContact CB-CD1 4.26Å
74I92.3Very high91.7Very high26 Ų2636.8 Ų36.813%0.13319%0.188CC..Hα-helixtrans-63.5-44.4178.3-70.1167.7000110.4N70 T72 L77 W78 L111 K125 L128N70-I74 WeakPolarHBondContact O-CB 3.33Å; N70-I74 WeakPolarHBondContact O-CD1 3.27Å; N70-I74 VanDerWaalsContact O-CG1 3.27Å; N70-I74 WeakPolarHBondContact O-CG1 3.49Å; N70-I74 PolarHBondContact O-N 3.33Å; T72-I74 PolarHBondContact O-N 2.95Å; I74-L77 PolarHBondContact O-N 3.31Å; I74-W78 VanDerWaalsContact O-CB 3.29Å; I74-W78 WeakPolarHBondContact O-CB 3.31Å; I74-W78 PolarHBondContact O-N 3.32Å; I74-L111 HydrophobicContact CG1-CD1 3.97Å; I74-L111 HydrophobicContact CG1-CD2 4.41Å; I74-K125 HydrophobicContact CD1-CB 4.1Å; I74-K125 HydrophobicContact CD1-CG 4.45Å; I74-L128 HydrophobicContact CD1-CD1 4.16Å
75K91.2Very high91.9Very high87 Ų8742.9 Ų42.938%0.37821%0.208SC..Hα-helixtrans-63.6-43.1178.3-83.7-163.5172.9-167.80112.5I14 V71 T72 W78 S79I14-K75 HydrophobicContact CG2-CD 3.63Å; V71-K75 HydrophobicContact CG1-CD 4.4Å; V71-K75 HydrophobicContact CG1-CG 4.38Å; V71-K75 VanDerWaalsContact O-CB 3.3Å; V71-K75 WeakPolarHBondContact O-CB 3.35Å; V71-K75 WeakPolarHBondContact O-CG 3.44Å; V71-K75 PolarHBondContact O-N 3.05Å; T72-K75 PolarHBondContact O-N 3.38Å; T72-K75 VanDerWaalsContact O-N 3.15Å; K75-W78 CarbonylContact O-C 3.33Å; K75-W78 WeakPolarHBondContact O-CA 3.41Å; K75-W78 WeakPolarHBondContact O-CB 3.45Å; K75-W78 PolarHBondContact O-N 3.21Å; K75-W78 VanDerWaalsContact O-N 3.1Å; K75-S79 PolarHBondContact O-N 3.14Å; K75-S79 PolarHBondContact O-OG 3.01Å
76T91Very high91.9Very high11 Ų1143.8 Ų43.87%0.06722%0.215CC..Hα-helixtrans-63.3-44.9178.3-56.80000110.8S18 P22 T72 R73 W78 S79 F80 L107S18-T76 PolarHBondContact O-OG1 2.83Å; P22-T76 HydrophobicContact CB-CG2 4.07Å; P22-T76 HydrophobicContact CG-CG2 4.1Å; T72-T76 WeakPolarHBondContact O-CB 3.06Å; T72-T76 PolarHBondContact O-N 2.97Å; T72-T76 PolarHBondContact O-OG1 3.45Å; R73-T76 PolarHBondContact O-N 2.84Å; T76-W78 VanDerWaalsContact C-N 3.26Å; T76-W78 PolarHBondContact O-N 3.02Å; T76-S79 WeakPolarHBondContact O-CB 3.05Å; T76-S79 PolarHBondContact O-N 3.47Å; T76-F80 HydrophobicContact CG2-CD2 4.03Å; T76-F80 HydrophobicContact CG2-CE2 3.65Å; T76-F80 VanDerWaalsContact O-CD2 3.24Å; T76-F80 WeakPolarHBondContact O-CD2 3.5Å; T76-F80 PolarHBondContact O-N 3.33Å; T76-L107 HydrophobicContact CG2-CD1 4Å
77L92Very high92.1Very high0 Ų047.2 Ų47.20%024%0.237CC..Hα-helixtrans-60.9-37.1171.3-79.1-174.3000112.5R73 I74 S79 F80 L81 I104 L107 L111 L116 L121R73-L77 PolarHBondContact O-N 3.28Å; I74-L77 PolarHBondContact O-N 3.31Å; L77-S79 VanDerWaalsContact C-N 3.33Å; L77-F80 PolarHBondContact O-N 3.34Å; L77-L81 WeakPolarHBondContact O-CB 3.28Å; L77-L81 PolarHBondContact O-N 2.97Å; L77-I104 HydrophobicContact CD2-CB 4.45Å; L77-I104 HydrophobicContact CD2-CG1 4.4Å; L77-I104 HydrophobicContact CD2-CG2 4.2Å; L77-L107 HydrophobicContact CD1-CB 4.01Å; L77-L107 HydrophobicContact CD2-CB 3.65Å; L77-L107 HydrophobicContact CD2-CD1 3.84Å; L77-L107 HydrophobicContact CD2-CG 4.41Å; L77-L107 HydrophobicContact CG-CB 3.79Å; L77-L107 HydrophobicContact CG-CD1 3.88Å; L77-L107 HydrophobicContact CG-CG 4.45Å; L77-L111 HydrophobicContact CD1-CD1 3.64Å; L77-L116 HydrophobicContact CB-CD1 4.1Å; L77-L116 HydrophobicContact CD1-CD1 4.2Å; L77-L116 HydrophobicContact CD2-CD1 3.96Å; L77-L116 HydrophobicContact CG-CD1 4.33Å; L77-L121 HydrophobicContact CB-CD1 4.23Å; L77-L121 HydrophobicContact CB-CD2 3.86Å; L77-L121 HydrophobicContact CD1-CD2 3.64Å; L77-L121 HydrophobicContact CG-CD2 4.43Å
78W92.9Very high92.3Very high119 Ų11954.7 Ų54.745%0.45126%0.263SS..Hα-helixtrans-66.1-38.2178.1-158.718.2000111.7I74 K75 T76 L81 K82 F118 L121I74-W78 VanDerWaalsContact O-CB 3.29Å; I74-W78 WeakPolarHBondContact O-CB 3.31Å; I74-W78 PolarHBondContact O-N 3.32Å; K75-W78 CarbonylContact O-C 3.33Å; K75-W78 WeakPolarHBondContact O-CA 3.41Å; K75-W78 WeakPolarHBondContact O-CB 3.45Å; K75-W78 PolarHBondContact O-N 3.21Å; K75-W78 VanDerWaalsContact O-N 3.1Å; T76-W78 VanDerWaalsContact C-N 3.26Å; T76-W78 PolarHBondContact O-N 3.02Å; W78-L81 PolarHBondContact O-N 3.24Å; W78-K82 WeakPolarHBondContact O-CG 3.22Å; W78-K82 PolarHBondContact O-N 3.02Å; W78-F118 AromaticContact CD1-CD1 3.4Å; W78-F118 AromaticContact CD1-CE1 3.29Å; W78-F118 AromaticContact NE1-CD1 3.12Å; W78-F118 AromaticContact NE1-CE1 3.14Å; W78-L121 HydrophobicContact CB-CD1 4.32Å
79S91.8Very high92.5Very high66 Ų6659.4 Ų59.446%0.46229%0.294SS..Hα-helixtrans-64.6-46.3172.7-630000112K75 T76 L77 L81 K82 L83K75-S79 PolarHBondContact O-N 3.14Å; K75-S79 PolarHBondContact O-OG 3.01Å; T76-S79 WeakPolarHBondContact O-CB 3.05Å; T76-S79 PolarHBondContact O-N 3.47Å; L77-S79 VanDerWaalsContact C-N 3.33Å; S79-L81 VanDerWaalsContact C-N 3.28Å; S79-L81 PolarHBondContact O-N 3.3Å; S79-K82 WeakPolarHBondContact O-CB 3.19Å; S79-K82 PolarHBondContact O-N 2.93Å; S79-K82 VanDerWaalsContact O-N 3.08Å; S79-L83 PolarHBondContact O-N 3.38Å
80F92.2Very high92.8Very high30 Ų3063.8 Ų63.813%0.13232%0.317CS..Hα-helixtrans-58.1-42.5174.4-78.4-58.7000112.1T76 L77 K82 L83 S84 F95 A103 I104T76-F80 HydrophobicContact CG2-CD2 4.03Å; T76-F80 HydrophobicContact CG2-CE2 3.65Å; T76-F80 VanDerWaalsContact O-CD2 3.24Å; T76-F80 WeakPolarHBondContact O-CD2 3.5Å; T76-F80 PolarHBondContact O-N 3.33Å; L77-F80 PolarHBondContact O-N 3.34Å; F80-K82 VanDerWaalsContact C-N 3.3Å; F80-K82 PolarHBondContact O-N 3.2Å; F80-L83 HydrophobicContact CD1-CD1 4.24Å; F80-L83 WeakPolarHBondContact O-CB 3.47Å; F80-L83 PolarHBondContact O-N 3.4Å; F80-L83 VanDerWaalsContact O-N 3.11Å; F80-S84 PolarHBondContact O-N 3Å; F80-F95 HydrophobicContact CB-CD2 4.27Å; F80-F95 HydrophobicContact CB-CE2 4.31Å; F80-F95 WeakPolarHBondContact O-CD2 3.38Å; F80-A103 HydrophobicContact CE2-CB 4.27Å; F80-A103 HydrophobicContact CZ-CB 4.26Å; F80-I104 HydrophobicContact CB-CD1 3.91Å; F80-I104 HydrophobicContact CB-CG1 3.97Å; F80-I104 HydrophobicContact CD1-CD1 3.99Å; F80-I104 HydrophobicContact CD1-CG1 4.2Å; F80-I104 HydrophobicContact CD2-CD1 4.31Å; F80-I104 HydrophobicContact CD2-CG1 3.65Å; F80-I104 HydrophobicContact CE2-CG1 4.13Å; F80-I104 HydrophobicContact CG-CD1 3.83Å; F80-I104 HydrophobicContact CG-CG1 3.69Å
81L93.6Very high92.9Very high4 Ų465.1 Ų65.12%0.02132%0.323CS..Hα-helixtrans-64.2-36.1176.5-170.658.4000112L77 W78 S79 L83 S84 Y85 L116 T117 F118 L121L77-L81 WeakPolarHBondContact O-CB 3.28Å; L77-L81 PolarHBondContact O-N 2.97Å; W78-L81 PolarHBondContact O-N 3.24Å; S79-L81 VanDerWaalsContact C-N 3.28Å; S79-L81 PolarHBondContact O-N 3.3Å; L81-L83 VanDerWaalsContact C-N 3.3Å; L81-L83 PolarHBondContact O-N 2.88Å; L81-S84 PolarHBondContact O-N 3.04Å; L81-S84 PolarHBondContact O-OG 3Å; L81-Y85 HydrophobicContact CD1-CD2 4.07Å; L81-Y85 HydrophobicContact CD1-CE2 3.42Å; L81-Y85 VanDerWaalsContact CD1-CE2 3.42Å; L81-Y85 HydrophobicContact CD2-CE2 4.47Å; L81-Y85 HydrophobicContact CG-CD2 4.1Å; L81-Y85 HydrophobicContact CG-CE2 3.74Å; L81-Y85 WeakPolarHBondContact O-CD2 3.47Å; L81-Y85 PolarHBondContact O-N 3.39Å; L81-L116 HydrophobicContact CB-CD2 4.33Å; L81-L116 HydrophobicContact CB-CG 4.38Å; L81-L116 HydrophobicContact CD1-CD2 4.23Å; L81-L116 HydrophobicContact CD1-CG 4Å; L81-T117 VanDerWaalsContact CD2-C 3.46Å; L81-F118 HydrophobicContact CB-CE1 4.24Å; L81-F118 HydrophobicContact CD2-CB 4.38Å; L81-F118 HydrophobicContact CD2-CD1 3.35Å; L81-F118 HydrophobicContact CD2-CD2 3.99Å; L81-F118 HydrophobicContact CD2-CE1 3.46Å; L81-F118 VanDerWaalsContact CD2-CE1 3.46Å; L81-F118 HydrophobicContact CD2-CE2 4.07Å; L81-F118 HydrophobicContact CD2-CG 3.64Å; L81-F118 HydrophobicContact CD2-CZ 3.83Å; L81-F118 VanDerWaalsContact CD2-N 3.33Å; L81-F118 HydrophobicContact CG-CD1 4.17Å; L81-F118 HydrophobicContact CG-CE1 3.75Å; L81-F118 HydrophobicContact CG-CE2 4.17Å; L81-F118 HydrophobicContact CG-CZ 3.75Å; L81-L121 HydrophobicContact CD2-CD1 4.13Å
82K93.8Very high93.1Very high123 Ų12368.9 Ų68.954%0.53533%0.333SS..Hα-helixtrans-64.6-34.3172.6-73.7178.7179.1-172.90112.5W78 S79 F80 Y85 S86W78-K82 WeakPolarHBondContact O-CG 3.22Å; W78-K82 PolarHBondContact O-N 3.02Å; S79-K82 WeakPolarHBondContact O-CB 3.19Å; S79-K82 PolarHBondContact O-N 2.93Å; S79-K82 VanDerWaalsContact O-N 3.08Å; F80-K82 VanDerWaalsContact C-N 3.3Å; F80-K82 PolarHBondContact O-N 3.2Å; K82-Y85 PolarHBondContact O-N 2.76Å; K82-S86 PolarHBondContact O-N 3.46Å; K82-S86 VanDerWaalsContact O-N 3.15Å
83L92.9Very high93.3Very high43 Ų4372.1 Ų72.123%0.22535%0.353CS..Hα-helixtrans-64.8-40.2176.1-66.3174.7000111.7S79 F80 L81 Y85 S86 M91 V94 F95S79-L83 PolarHBondContact O-N 3.38Å; F80-L83 HydrophobicContact CD1-CD1 4.24Å; F80-L83 WeakPolarHBondContact O-CB 3.47Å; F80-L83 PolarHBondContact O-N 3.4Å; F80-L83 VanDerWaalsContact O-N 3.11Å; L81-L83 VanDerWaalsContact C-N 3.3Å; L81-L83 PolarHBondContact O-N 2.88Å; L83-Y85 VanDerWaalsContact C-N 3.32Å; L83-Y85 PolarHBondContact O-N 3.28Å; L83-S86 VanDerWaalsContact O-CB 3.26Å; L83-S86 WeakPolarHBondContact O-CB 3.49Å; L83-S86 PolarHBondContact O-N 3.26Å; L83-M91 HydrophobicContact CD2-CB 4.13Å; L83-M91 HydrophobicContact CD2-CG 4.33Å; L83-M91 HydrophobicContact CD2-SD 3.53Å; L83-M91 VanDerWaalsContact CD2-SD 3.53Å; L83-V94 HydrophobicContact CD1-CG1 4.26Å; L83-F95 HydrophobicContact CB-CB 4.08Å
84S93.8Very high93.4Very high32 Ų3273 Ų7322%0.22436%0.363CS..Hα-helixtrans-65.1-34.8178.471.90000113.1F80 L81 S86F80-S84 PolarHBondContact O-N 3Å; L81-S84 PolarHBondContact O-N 3.04Å; L81-S84 PolarHBondContact O-OG 3Å; S84-S86 VanDerWaalsContact C-N 3.34Å
85Y93.9Very high93.5Very high141 Ų14173.4 Ų73.455%0.55336%0.364SS*.THydrogen-bonded Turntrans-86.7-0.9176.8-68.2-70.8000113.9L81 K82 L83 F118L81-Y85 HydrophobicContact CD1-CD2 4.07Å; L81-Y85 HydrophobicContact CD1-CE2 3.42Å; L81-Y85 VanDerWaalsContact CD1-CE2 3.42Å; L81-Y85 HydrophobicContact CD2-CE2 4.47Å; L81-Y85 HydrophobicContact CG-CD2 4.1Å; L81-Y85 HydrophobicContact CG-CE2 3.74Å; L81-Y85 WeakPolarHBondContact O-CD2 3.47Å; L81-Y85 PolarHBondContact O-N 3.39Å; K82-Y85 PolarHBondContact O-N 2.76Å; L83-Y85 VanDerWaalsContact C-N 3.32Å; L83-Y85 PolarHBondContact O-N 3.28Å; Y85-F118 AromaticContact CD2-CE2 3.63Å; Y85-F118 HydrophobicContact CD2-CE2 3.63Å; Y85-F118 AromaticContact CD2-CZ 3.82Å; Y85-F118 HydrophobicContact CD2-CZ 3.82Å; Y85-F118 HydrophobicContact CE2-CD2 4.25Å; Y85-F118 AromaticContact CE2-CE2 3.49Å; Y85-F118 HydrophobicContact CE2-CE2 3.49Å; Y85-F118 VanDerWaalsContact CE2-CE2 3.49Å; Y85-F118 HydrophobicContact CE2-CZ 4.01Å
86S94.1Very high93.6Very high22 Ų2275.4 Ų75.415%0.15438%0.375CS..  trans-64.2140.6-179.5-176.10000110.7K82 L83 S84 R88 M91 R92K82-S86 PolarHBondContact O-N 3.46Å; K82-S86 VanDerWaalsContact O-N 3.15Å; L83-S86 VanDerWaalsContact O-CB 3.26Å; L83-S86 WeakPolarHBondContact O-CB 3.49Å; L83-S86 PolarHBondContact O-N 3.26Å; S84-S86 VanDerWaalsContact C-N 3.34Å; S86-R88 PolarHBondContact O-N 3.42Å; S86-R88 PolarHBondContact OG-N 3.27Å; S86-M91 WeakPolarHBondContact OG-CB 3.48Å; S86-R92 PolarHBondContact O-NE 3.45Å; S86-R92 PolarHBondContact O-NH2 2.89Å
87P94.4Very high93.8Very high114 Ų11479.1 Ų79.174%0.7439%0.391SS*.SBendtrans-69.2-19.8174.727.2-34.1000112.7
88R95.2Very high93.9Very high170 Ų17082.8 Ų82.864%0.64242%0.415SS*.SBendtrans-82.1125-175.5-63.9-178.3177.7178.8-1.4111.2S86 L90 M91S86-R88 PolarHBondContact O-N 3.42Å; S86-R88 PolarHBondContact OG-N 3.27Å; R88-L90 VanDerWaalsContact C-N 3.3Å; R88-L90 PolarHBondContact O-N 3.14Å; R88-M91 HydrophobicContact CB-CB 4.45Å; R88-M91 HydrophobicContact CB-CG 4.02Å; R88-M91 WeakPolarHBondContact O-CB 3.48Å; R88-M91 PolarHBondContact O-N 3.37Å
89P94Very high93.9Very high101 Ų10182.2 Ų82.266%0.65642%0.419SS*.Hα-helixtrans-54.9-41.8179.4-27.635000113.7M91 R92 T93P89-M91 PolarHBondContact O-N 2.55Å; P89-R92 WeakPolarHBondContact O-CB 3.2Å; P89-R92 PolarHBondContact O-N 2.91Å; P89-T93 PolarHBondContact O-N 3.46Å
90L95Very high93.8Very high123 Ų12379.7 Ų79.764%0.64440%0.402SS*.Hα-helixtrans-57.1-34.3177.9-175.268.9000113.2R88 R92 T93 V94R88-L90 VanDerWaalsContact C-N 3.3Å; R88-L90 PolarHBondContact O-N 3.14Å; L90-R92 VanDerWaalsContact C-N 3.33Å; L90-T93 PolarHBondContact O-OG1 3.04Å; L90-V94 VanDerWaalsContact O-CG2 3.3Å; L90-V94 WeakPolarHBondContact O-CG2 3.23Å; L90-V94 PolarHBondContact O-N 3.32Å
91M94.4Very high93.9Very high63 Ų6381.7 Ų81.731%0.3141%0.412SS..Hα-helixtrans-72.9-31.5179.4-66.3-66.9-178.800111.6L83 S86 R88 P89 F95L83-M91 HydrophobicContact CD2-CB 4.13Å; L83-M91 HydrophobicContact CD2-CG 4.33Å; L83-M91 HydrophobicContact CD2-SD 3.53Å; L83-M91 VanDerWaalsContact CD2-SD 3.53Å; S86-M91 WeakPolarHBondContact OG-CB 3.48Å; R88-M91 HydrophobicContact CB-CB 4.45Å; R88-M91 HydrophobicContact CB-CG 4.02Å; R88-M91 WeakPolarHBondContact O-CB 3.48Å; R88-M91 PolarHBondContact O-N 3.37Å; P89-M91 PolarHBondContact O-N 2.55Å; M91-F95 PolarHBondContact O-N 2.8Å; M91-F95 VanDerWaalsContact O-N 3.15Å
92R94.6Very high93.8Very high118 Ų11889.5 Ų89.545%0.44544%0.441SS..Hα-helixtrans-72.5-40.5175.9-60.9-177.6-174.9179.1-0.6111.3S86 P89 L90 V94 F95 E96S86-R92 PolarHBondContact O-NE 3.45Å; S86-R92 PolarHBondContact O-NH2 2.89Å; P89-R92 WeakPolarHBondContact O-CB 3.2Å; P89-R92 PolarHBondContact O-N 2.91Å; L90-R92 VanDerWaalsContact C-N 3.33Å; R92-V94 VanDerWaalsContact C-N 3.31Å; R92-V94 PolarHBondContact O-N 2.7Å; R92-F95 WeakPolarHBondContact O-CA 3.27Å; R92-F95 WeakPolarHBondContact O-CB 3.15Å; R92-F95 PolarHBondContact O-N 2.95Å; R92-F95 VanDerWaalsContact O-N 3.07Å; R92-E96 WeakPolarHBondContact O-CG 3.25Å; R92-E96 PolarHBondContact O-N 3.17Å
93T95.1Very high93.7Very high75 Ų7584.3 Ų84.346%0.4642%0.421SS..Hα-helixtrans-62.9-38.2175.261.40000111.9P89 L90 F95 E96 H97P89-T93 PolarHBondContact O-N 3.46Å; L90-T93 PolarHBondContact O-OG1 3.04Å; T93-F95 VanDerWaalsContact C-N 3.32Å; T93-F95 PolarHBondContact O-N 2.96Å; T93-E96 PolarHBondContact O-N 2.92Å; T93-H97 PolarHBondContact O-N 2.93Å
94V93.7Very high93.7Very high64 Ų6482.3 Ų82.339%0.38841%0.411SS..Hα-helixtrans-64.2-37.1173172.20000111.8L83 L90 R92 H97 S100L83-V94 HydrophobicContact CD1-CG1 4.26Å; L90-V94 VanDerWaalsContact O-CG2 3.3Å; L90-V94 WeakPolarHBondContact O-CG2 3.23Å; L90-V94 PolarHBondContact O-N 3.32Å; R92-V94 VanDerWaalsContact C-N 3.31Å; R92-V94 PolarHBondContact O-N 2.7Å; V94-H97 WeakPolarHBondContact O-CB 3.14Å; V94-H97 PolarHBondContact O-N 2.88Å; V94-S100 VanDerWaalsContact O-CB 3.29Å; V94-S100 WeakPolarHBondContact O-CB 3.45Å; V94-S100 PolarHBondContact O-OG 2.97Å
95F94.1Very high93.6Very high36 Ų3683.5 Ų83.516%0.15842%0.422CS..Hα-helixtrans-65.8-43.8175172.4-99.2000111.6F80 L83 M91 R92 T93 H97 S100 Q101 I104 L116F80-F95 HydrophobicContact CB-CD2 4.27Å; F80-F95 HydrophobicContact CB-CE2 4.31Å; F80-F95 WeakPolarHBondContact O-CD2 3.38Å; L83-F95 HydrophobicContact CB-CB 4.08Å; M91-F95 PolarHBondContact O-N 2.8Å; M91-F95 VanDerWaalsContact O-N 3.15Å; R92-F95 WeakPolarHBondContact O-CA 3.27Å; R92-F95 WeakPolarHBondContact O-CB 3.15Å; R92-F95 PolarHBondContact O-N 2.95Å; R92-F95 VanDerWaalsContact O-N 3.07Å; T93-F95 VanDerWaalsContact C-N 3.32Å; T93-F95 PolarHBondContact O-N 2.96Å; F95-H97 VanDerWaalsContact C-N 3.27Å; F95-H97 PolarHBondContact O-N 2.85Å; F95-S100 WeakPolarHBondContact O-CB 3.32Å; F95-Q101 PolarHBondContact O-NE2 2.89Å; F95-I104 HydrophobicContact CD2-CD1 3.92Å; F95-I104 HydrophobicContact CE2-CD1 3.52Å; F95-I104 HydrophobicContact CZ-CD1 4.25Å; F95-L116 HydrophobicContact CE2-CD2 4.18Å; F95-L116 HydrophobicContact CZ-CD2 4.49Å
96E94.2Very high93.5Very high129 Ų12978.2 Ų78.260%0.60341%0.407SS*.Hα-helixtrans-73.2-16.9179.2-70.5169.3-174.400113.4R92 T93R92-E96 WeakPolarHBondContact O-CG 3.25Å; R92-E96 PolarHBondContact O-N 3.17Å; T93-E96 PolarHBondContact O-N 2.92Å
97H95.1Very high93.4Very high89 Ų8977.1 Ų77.141%0.41240%0.4SS..SBendtrans-53.5137.2-179.4-168.8-98.9000112.3T93 V94 F95 I99 S100 Q101T93-H97 PolarHBondContact O-N 2.93Å; V94-H97 WeakPolarHBondContact O-CB 3.14Å; V94-H97 PolarHBondContact O-N 2.88Å; F95-H97 VanDerWaalsContact C-N 3.27Å; F95-H97 PolarHBondContact O-N 2.85Å; H97-I99 PolarHBondContact ND1-N 3.3Å; H97-I99 PolarHBondContact O-N 3.44Å; H97-I99 VanDerWaalsContact O-N 3.07Å; H97-S100 WeakPolarHBondContact O-CB 3.21Å; H97-S100 PolarHBondContact O-N 3.4Å; H97-Q101 PolarHBondContact O-N 3.16Å
98P94.1Very high93.3Very high77 Ų7774.3 Ų74.350%0.538%0.376SS..Hα-helixtrans-56.8-30.9-174.6-29.335.6000115.2R102P98-R102 WeakPolarHBondContact O-CB 3.38Å; P98-R102 WeakPolarHBondContact O-CG 3.27Å; P98-R102 PolarHBondContact O-N 3.18Å; P98-R102 PolarHBondContact O-NE 3.32Å
99I91.4Very high93.2Very high106 Ų10670.9 Ų70.954%0.54438%0.378SS..Hα-helixtrans-67.7-45.4176.1-60.8176.8000110.5H97 R102 A103H97-I99 PolarHBondContact ND1-N 3.3Å; H97-I99 PolarHBondContact O-N 3.44Å; H97-I99 VanDerWaalsContact O-N 3.07Å; I99-R102 PolarHBondContact O-N 3.05Å; I99-A103 PolarHBondContact O-N 3.38Å
100S91Very high93Very high14 Ų1470.2 Ų70.210%0.09837%0.366CS..Hα-helixtrans-62.6-46.2177.3-59.60000110.6V94 F95 H97 R102 A103 I104V94-S100 VanDerWaalsContact O-CB 3.29Å; V94-S100 WeakPolarHBondContact O-CB 3.45Å; V94-S100 PolarHBondContact O-OG 2.97Å; F95-S100 WeakPolarHBondContact O-CB 3.32Å; H97-S100 WeakPolarHBondContact O-CB 3.21Å; H97-S100 PolarHBondContact O-N 3.4Å; S100-R102 PolarHBondContact O-N 3.03Å; S100-A103 PolarHBondContact O-N 3.34Å; S100-I104 WeakPolarHBondContact O-CB 3.49Å; S100-I104 WeakPolarHBondContact O-CD1 3.26Å; S100-I104 WeakPolarHBondContact O-CG1 3.13Å; S100-I104 PolarHBondContact O-N 2.89Å
101Q93.3Very high92.8Very high72 Ų7264.5 Ų64.534%0.33634%0.337SS..Hα-helixtrans-62.3-41.5178.4-68.4-59.1-33.700112.7F95 H97 A103 I104 A105F95-Q101 PolarHBondContact O-NE2 2.89Å; H97-Q101 PolarHBondContact O-N 3.16Å; Q101-A103 PolarHBondContact O-N 3.43Å; Q101-I104 PolarHBondContact O-N 3.49Å; Q101-A105 WeakPolarHBondContact O-CB 3.28Å; Q101-A105 PolarHBondContact O-N 3.43Å
102R92.6Very high92.6Very high167 Ų16763.6 Ų63.663%0.6334%0.343SS*.Hα-helixtrans-60.5-44.4172.9-80.6-178.2-89.3162.6-13.6112.1P98 I99 S100 A105 A106P98-R102 WeakPolarHBondContact O-CB 3.38Å; P98-R102 WeakPolarHBondContact O-CG 3.27Å; P98-R102 PolarHBondContact O-N 3.18Å; P98-R102 PolarHBondContact O-NE 3.32Å; I99-R102 PolarHBondContact O-N 3.05Å; S100-R102 PolarHBondContact O-N 3.03Å; R102-A105 PolarHBondContact O-N 3.2Å; R102-A106 WeakPolarHBondContact O-CB 3.28Å; R102-A106 PolarHBondContact O-N 3.29Å
103A90.8Very high92.5Very high14 Ų1458.7 Ų58.712%0.11633%0.327CS..Hα-helixtrans-63.9-43.6176.600000112.1P22 F80 I99 S100 Q101 A106 L107P22-A103 HydrophobicContact CG-CB 4.3Å; F80-A103 HydrophobicContact CE2-CB 4.27Å; F80-A103 HydrophobicContact CZ-CB 4.26Å; I99-A103 PolarHBondContact O-N 3.38Å; S100-A103 PolarHBondContact O-N 3.34Å; Q101-A103 PolarHBondContact O-N 3.43Å; A103-A106 PolarHBondContact O-N 2.96Å; A103-L107 WeakPolarHBondContact O-CB 3.26Å; A103-L107 VanDerWaalsContact O-CG 3.3Å; A103-L107 WeakPolarHBondContact O-CG 3.39Å; A103-L107 PolarHBondContact O-N 3.49Å
104I92.3Very high92.2Very high2 Ų264.1 Ų64.11%0.0135%0.346CS..Hα-helixtrans-61.7-46.9176.6-68.8161.7000110.6L77 F80 F95 S100 Q101 L107 K108 L116L77-I104 HydrophobicContact CD2-CB 4.45Å; L77-I104 HydrophobicContact CD2-CG1 4.4Å; L77-I104 HydrophobicContact CD2-CG2 4.2Å; F80-I104 HydrophobicContact CB-CD1 3.91Å; F80-I104 HydrophobicContact CB-CG1 3.97Å; F80-I104 HydrophobicContact CD1-CD1 3.99Å; F80-I104 HydrophobicContact CD1-CG1 4.2Å; F80-I104 HydrophobicContact CD2-CD1 4.31Å; F80-I104 HydrophobicContact CD2-CG1 3.65Å; F80-I104 HydrophobicContact CE2-CG1 4.13Å; F80-I104 HydrophobicContact CG-CD1 3.83Å; F80-I104 HydrophobicContact CG-CG1 3.69Å; F95-I104 HydrophobicContact CD2-CD1 3.92Å; F95-I104 HydrophobicContact CE2-CD1 3.52Å; F95-I104 HydrophobicContact CZ-CD1 4.25Å; S100-I104 WeakPolarHBondContact O-CB 3.49Å; S100-I104 WeakPolarHBondContact O-CD1 3.26Å; S100-I104 WeakPolarHBondContact O-CG1 3.13Å; S100-I104 PolarHBondContact O-N 2.89Å; Q101-I104 PolarHBondContact O-N 3.49Å; I104-L107 PolarHBondContact O-N 3.11Å; I104-K108 HydrophobicContact CG2-CD 4.03Å; I104-K108 HydrophobicContact CG2-CG 4.25Å; I104-K108 VanDerWaalsContact O-CB 3.31Å; I104-K108 WeakPolarHBondContact O-CB 3.2Å; I104-K108 VanDerWaalsContact O-CG 3.31Å; I104-K108 WeakPolarHBondContact O-CG 3.2Å; I104-K108 PolarHBondContact O-N 3.14Å; I104-L116 HydrophobicContact CG2-CD2 4.06Å
105A92.9Very high92Very high57 Ų5763.6 Ų63.647%0.47135%0.349SS..Hα-helixtrans-61-45.1179.100000111.8Q101 R102 L107 K108 S109Q101-A105 WeakPolarHBondContact O-CB 3.28Å; Q101-A105 PolarHBondContact O-N 3.43Å; R102-A105 PolarHBondContact O-N 3.2Å; A105-L107 PolarHBondContact O-N 3.28Å; A105-K108 PolarHBondContact O-N 3.24Å; A105-S109 PolarHBondContact O-N 3.24Å
106A91.7Very high91.8Very high29 Ų2963 Ų6324%0.2435%0.348CS..Hα-helixtrans-60.8-45.5175.900000112R102 A103 S109 Q110R102-A106 WeakPolarHBondContact O-CB 3.28Å; R102-A106 PolarHBondContact O-N 3.29Å; A103-A106 PolarHBondContact O-N 2.96Å; A106-S109 PolarHBondContact O-N 3.38Å; A106-Q110 WeakPolarHBondContact O-CG 3.39Å; A106-Q110 PolarHBondContact O-N 3.31Å
107L91.6Very high91.8Very high0 Ų059.1 Ų59.10%033%0.333CS..Hα-helixtrans-66.8-40.2178.9-76.6176.7000112.9P22 R73 T76 L77 A103 I104 A105 S109 Q110 L111P22-L107 HydrophobicContact CB-CD1 3.73Å; P22-L107 HydrophobicContact CB-CD2 3.85Å; P22-L107 HydrophobicContact CB-CG 4.05Å; P22-L107 HydrophobicContact CG-CD1 3.98Å; P22-L107 HydrophobicContact CG-CG 4.43Å; R73-L107 HydrophobicContact CB-CD2 3.82Å; R73-L107 HydrophobicContact CG-CD2 3.54Å; T76-L107 HydrophobicContact CG2-CD1 4Å; L77-L107 HydrophobicContact CD1-CB 4.01Å; L77-L107 HydrophobicContact CD2-CB 3.65Å; L77-L107 HydrophobicContact CD2-CD1 3.84Å; L77-L107 HydrophobicContact CD2-CG 4.41Å; L77-L107 HydrophobicContact CG-CB 3.79Å; L77-L107 HydrophobicContact CG-CD1 3.88Å; L77-L107 HydrophobicContact CG-CG 4.45Å; A103-L107 WeakPolarHBondContact O-CB 3.26Å; A103-L107 VanDerWaalsContact O-CG 3.3Å; A103-L107 WeakPolarHBondContact O-CG 3.39Å; A103-L107 PolarHBondContact O-N 3.49Å; I104-L107 PolarHBondContact O-N 3.11Å; A105-L107 PolarHBondContact O-N 3.28Å; L107-S109 VanDerWaalsContact C-N 3.34Å; L107-Q110 PolarHBondContact O-N 3.24Å; L107-L111 WeakPolarHBondContact O-CB 3.32Å; L107-L111 PolarHBondContact O-N 3.39Å
108K93.2Very high91.7Very high54 Ų5458.6 Ų58.624%0.23533%0.329CS..Hα-helixtrans-57.6-47173.4-85.1-179.2177.3-173.70111.3I104 A105 L111 G112 V113 Q114I104-K108 HydrophobicContact CG2-CD 4.03Å; I104-K108 HydrophobicContact CG2-CG 4.25Å; I104-K108 VanDerWaalsContact O-CB 3.31Å; I104-K108 WeakPolarHBondContact O-CB 3.2Å; I104-K108 VanDerWaalsContact O-CG 3.31Å; I104-K108 WeakPolarHBondContact O-CG 3.2Å; I104-K108 PolarHBondContact O-N 3.14Å; A105-K108 PolarHBondContact O-N 3.24Å; K108-L111 CarbonylContact O-C 3.59Å; K108-L111 PolarHBondContact O-N 2.92Å; K108-G112 WeakPolarHBondContact O-CA 3.32Å; K108-G112 PolarHBondContact O-N 3.37Å; K108-V113 VanDerWaalsContact CB-O 3.28Å; K108-V113 WeakPolarHBondContact CB-O 3.23Å; K108-V113 PolarHBondContact O-N 2.9Å; K108-Q114 PolarHBondContact NZ-O 2.88Å
109S92.4Very high91.7Very high98 Ų9863 Ų6369%0.68534%0.341SS*.Hα-helixtrans-60.8-50.6177177.60000111.4A105 A106 L107 L111 G112A105-S109 PolarHBondContact O-N 3.24Å; A106-S109 PolarHBondContact O-N 3.38Å; L107-S109 VanDerWaalsContact C-N 3.34Å; S109-L111 VanDerWaalsContact C-N 3.27Å; S109-L111 PolarHBondContact O-N 3.12Å; S109-G112 PolarHBondContact O-N 3.02Å
110Q90.3Very high91.9Very high87 Ų8759.9 Ų59.941%0.40733%0.327SS..Hα-helixtrans-60.5-34178.9-72.2176-7.700113.7A106 L107A106-Q110 WeakPolarHBondContact O-CG 3.39Å; A106-Q110 PolarHBondContact O-N 3.31Å; L107-Q110 PolarHBondContact O-N 3.24Å
111L90.6Very high92Very high4 Ų459.4 Ų59.42%0.02132%0.323CS..THydrogen-bonded Turntrans-92.12.1176.7-68.8174.6000113R73 I74 L77 L107 K108 S109 V113 R127 L128R73-L111 HydrophobicContact CB-CD1 4.26Å; I74-L111 HydrophobicContact CG1-CD1 3.97Å; I74-L111 HydrophobicContact CG1-CD2 4.41Å; L77-L111 HydrophobicContact CD1-CD1 3.64Å; L107-L111 WeakPolarHBondContact O-CB 3.32Å; L107-L111 PolarHBondContact O-N 3.39Å; K108-L111 CarbonylContact O-C 3.59Å; K108-L111 PolarHBondContact O-N 2.92Å; S109-L111 VanDerWaalsContact C-N 3.27Å; S109-L111 PolarHBondContact O-N 3.12Å; L111-V113 VanDerWaalsContact C-N 3.33Å; L111-V113 HydrophobicContact CB-CG2 4.17Å; L111-V113 PolarHBondContact O-N 3.13Å; L111-R127 PolarHBondContact O-NH2 2.98Å; L111-L128 HydrophobicContact CD2-CD1 3.96Å
112G90.8Very high92Very high44 Ų4460 Ų6045%0.45433%0.328SS..THydrogen-bonded Turntrans51.448.1-177.300000113.3K108 S109 R127K108-G112 WeakPolarHBondContact O-CA 3.32Å; K108-G112 PolarHBondContact O-N 3.37Å; S109-G112 PolarHBondContact O-N 3.02Å; G112-R127 PolarHBondContact O-NH1 3.05Å
113V92.1Very high92.1Very high15 Ų1554 Ų549%0.09132%0.315CS..  trans-121.4123.6179177.30000109.6K108 L111 A115 A124K108-V113 VanDerWaalsContact CB-O 3.28Å; K108-V113 WeakPolarHBondContact CB-O 3.23Å; K108-V113 PolarHBondContact O-N 2.9Å; L111-V113 VanDerWaalsContact C-N 3.33Å; L111-V113 HydrophobicContact CB-CG2 4.17Å; L111-V113 PolarHBondContact O-N 3.13Å; V113-A115 WeakPolarHBondContact CG1-O 3.35Å; V113-A124 HydrophobicContact CG2-CB 3.68Å
114Q87.7Confident92.3Very high188 Ų18853.5 Ų53.588%0.87931%0.311SS*.SBendtrans-82.4-55179.6-65.1175.1-2.500112K108K108-Q114 PolarHBondContact NZ-O 2.88Å
115A89.5Confident92.3Very high54 Ų5459.8 Ų59.845%0.44634%0.338SS..SBendtrans-94.6132.8179.600000112.1V113 T117 T120V113-A115 WeakPolarHBondContact CG1-O 3.35Å; A115-T117 PolarHBondContact O-N 3.32Å; A115-T120 HydrophobicContact CB-CG2 4.49Å; A115-T120 WeakPolarHBondContact O-CB 3.35Å; A115-T120 PolarHBondContact O-OG1 2.78Å
116L90.6Very high92.3Very high24 Ų2464.5 Ų64.513%0.12634%0.343CS..  trans-87.397.2176.1-170.866000110.1L77 L81 F95 I104 L121L77-L116 HydrophobicContact CB-CD1 4.1Å; L77-L116 HydrophobicContact CD1-CD1 4.2Å; L77-L116 HydrophobicContact CD2-CD1 3.96Å; L77-L116 HydrophobicContact CG-CD1 4.33Å; L81-L116 HydrophobicContact CB-CD2 4.33Å; L81-L116 HydrophobicContact CB-CG 4.38Å; L81-L116 HydrophobicContact CD1-CD2 4.23Å; L81-L116 HydrophobicContact CD1-CG 4Å; F95-L116 HydrophobicContact CE2-CD2 4.18Å; F95-L116 HydrophobicContact CZ-CD2 4.49Å; I104-L116 HydrophobicContact CG2-CD2 4.06Å; L116-L121 HydrophobicContact CD1-CD1 4.28Å; L116-L121 HydrophobicContact CD1-CD2 4.19Å; L116-L121 HydrophobicContact CD1-CG 4.37Å
117T93.7Very high92.4Very high47 Ų4768.2 Ų68.229%0.28835%0.351SS..  trans-138.6160.4174.668.40000109.6L81 A115 K119 T120 L121L81-T117 VanDerWaalsContact CD2-C 3.46Å; A115-T117 PolarHBondContact O-N 3.32Å; T117-K119 PolarHBondContact O-N 3.33Å; T117-T120 PolarHBondContact N-OG1 3.22Å; T117-T120 PolarHBondContact O-N 3.23Å; T117-T120 PolarHBondContact O-OG1 2.98Å; T117-T120 VanDerWaalsContact OG1-CG2 3.29Å; T117-T120 WeakPolarHBondContact OG1-CG2 3.42Å; T117-T120 PolarHBondContact OG1-N 2.89Å; T117-T120 VanDerWaalsContact OG1-N 3.09Å; T117-T120 PolarHBondContact OG1-OG1 2.85Å; T117-L121 WeakPolarHBondContact O-CG 3.33Å; T117-L121 PolarHBondContact O-N 3.22Å
118F93.4Very high92.4Very high77 Ų7769.6 Ų69.634%0.33836%0.358SS..Hα-helixtrans-61.5-35.3177.1-62.1-66.2000111.6W78 L81 Y85 N122W78-F118 AromaticContact CD1-CD1 3.4Å; W78-F118 AromaticContact CD1-CE1 3.29Å; W78-F118 AromaticContact NE1-CD1 3.12Å; W78-F118 AromaticContact NE1-CE1 3.14Å; L81-F118 HydrophobicContact CB-CE1 4.24Å; L81-F118 HydrophobicContact CD2-CB 4.38Å; L81-F118 HydrophobicContact CD2-CD1 3.35Å; L81-F118 HydrophobicContact CD2-CD2 3.99Å; L81-F118 HydrophobicContact CD2-CE1 3.46Å; L81-F118 VanDerWaalsContact CD2-CE1 3.46Å; L81-F118 HydrophobicContact CD2-CE2 4.07Å; L81-F118 HydrophobicContact CD2-CG 3.64Å; L81-F118 HydrophobicContact CD2-CZ 3.83Å; L81-F118 VanDerWaalsContact CD2-N 3.33Å; L81-F118 HydrophobicContact CG-CD1 4.17Å; L81-F118 HydrophobicContact CG-CE1 3.75Å; L81-F118 HydrophobicContact CG-CE2 4.17Å; L81-F118 HydrophobicContact CG-CZ 3.75Å; Y85-F118 AromaticContact CD2-CE2 3.63Å; Y85-F118 HydrophobicContact CD2-CE2 3.63Å; Y85-F118 AromaticContact CD2-CZ 3.82Å; Y85-F118 HydrophobicContact CD2-CZ 3.82Å; Y85-F118 HydrophobicContact CE2-CD2 4.25Å; Y85-F118 AromaticContact CE2-CE2 3.49Å; Y85-F118 HydrophobicContact CE2-CE2 3.49Å; Y85-F118 VanDerWaalsContact CE2-CE2 3.49Å; Y85-F118 HydrophobicContact CE2-CZ 4.01Å; F118-N122 WeakPolarHBondContact O-CB 3.32Å; F118-N122 PolarHBondContact O-N 3.46Å; F118-N122 PolarHBondContact O-ND2 3.45Å
119K94.2Very high92.3Very high171 Ų17168.4 Ų68.474%0.74336%0.359SS*.Hα-helixtrans-65.6-44.2177.4-170.8177.8179.8-179.20111.6T117 N122 A123T117-K119 PolarHBondContact O-N 3.33Å; K119-N122 PolarHBondContact O-N 2.89Å; K119-A123 WeakPolarHBondContact O-CB 3.49Å; K119-A123 PolarHBondContact O-N 3.44Å
120T94.3Very high92.3Very high40 Ų4069.9 Ų69.925%0.24535%0.352CS..Hα-helixtrans-69.3-37.2179.555.10000112.2A115 T117 A123 A124A115-T120 HydrophobicContact CB-CG2 4.49Å; A115-T120 WeakPolarHBondContact O-CB 3.35Å; A115-T120 PolarHBondContact O-OG1 2.78Å; T117-T120 PolarHBondContact N-OG1 3.22Å; T117-T120 PolarHBondContact O-N 3.23Å; T117-T120 PolarHBondContact O-OG1 2.98Å; T117-T120 VanDerWaalsContact OG1-CG2 3.29Å; T117-T120 WeakPolarHBondContact OG1-CG2 3.42Å; T117-T120 PolarHBondContact OG1-N 2.89Å; T117-T120 VanDerWaalsContact OG1-N 3.09Å; T117-T120 PolarHBondContact OG1-OG1 2.85Å; T120-A123 PolarHBondContact O-N 3.35Å; T120-A124 WeakPolarHBondContact O-CB 3.5Å; T120-A124 PolarHBondContact O-N 3.15Å
121L93.8Very high92.4Very high4 Ų469.7 Ų69.72%0.02135%0.352CS..Hα-helixtrans-63.5-44173.4-69.3177.7000112.2L77 W78 L81 L116 T117 A123 A124 K125L77-L121 HydrophobicContact CB-CD1 4.23Å; L77-L121 HydrophobicContact CB-CD2 3.86Å; L77-L121 HydrophobicContact CD1-CD2 3.64Å; L77-L121 HydrophobicContact CG-CD2 4.43Å; W78-L121 HydrophobicContact CB-CD1 4.32Å; L81-L121 HydrophobicContact CD2-CD1 4.13Å; L116-L121 HydrophobicContact CD1-CD1 4.28Å; L116-L121 HydrophobicContact CD1-CD2 4.19Å; L116-L121 HydrophobicContact CD1-CG 4.37Å; T117-L121 WeakPolarHBondContact O-CG 3.33Å; T117-L121 PolarHBondContact O-N 3.22Å; L121-A123 VanDerWaalsContact C-N 3.34Å; L121-A123 PolarHBondContact O-N 3.44Å; L121-A124 PolarHBondContact O-N 2.94Å; L121-K125 PolarHBondContact O-N 3.42Å
122N94.5Very high92.4Very high84 Ų8471 Ų7145%0.44936%0.358SS..Hα-helixtrans-64.6-38.1175-78.6-31.6000112.2F118 K119 K125 R126F118-N122 WeakPolarHBondContact O-CB 3.32Å; F118-N122 PolarHBondContact O-N 3.46Å; F118-N122 PolarHBondContact O-ND2 3.45Å; K119-N122 PolarHBondContact O-N 2.89Å; N122-K125 PolarHBondContact O-N 3.44Å; N122-R126 WeakPolarHBondContact O-CG 3.32Å; N122-R126 PolarHBondContact O-N 2.98Å; N122-R126 VanDerWaalsContact O-N 3.08Å
123A94.3Very high92.5Very high42 Ų4270.7 Ų70.735%0.34735%0.345SS..Hα-helixtrans-64-42.2173.500000111.8K119 T120 L121 K125 R126 R127K119-A123 WeakPolarHBondContact O-CB 3.49Å; K119-A123 PolarHBondContact O-N 3.44Å; T120-A123 PolarHBondContact O-N 3.35Å; L121-A123 VanDerWaalsContact C-N 3.34Å; L121-A123 PolarHBondContact O-N 3.44Å; A123-K125 PolarHBondContact O-N 3.46Å; A123-R126 PolarHBondContact O-N 3.17Å; A123-R127 WeakPolarHBondContact O-CB 3.39Å; A123-R127 PolarHBondContact O-N 3.12Å
124A93.5Very high92.4Very high3 Ų374.2 Ų74.23%0.02536%0.361CS..Hα-helixtrans-61.8-43.4175.500000111.9V113 T120 L121 R126 R127 L128V113-A124 HydrophobicContact CG2-CB 3.68Å; T120-A124 WeakPolarHBondContact O-CB 3.5Å; T120-A124 PolarHBondContact O-N 3.15Å; L121-A124 PolarHBondContact O-N 2.94Å; A124-R126 VanDerWaalsContact C-N 3.34Å; A124-R126 PolarHBondContact O-N 3.42Å; A124-R127 PolarHBondContact O-N 2.81Å; A124-L128 WeakPolarHBondContact O-CG 3.45Å; A124-L128 PolarHBondContact O-N 3.14Å
125K92.9Very high92.6Very high133 Ų13370.3 Ų70.358%0.57834%0.342SS*.Hα-helixtrans-56.7-45.8173.5-175.2-176.6176.2-175.70111.9I74 L121 N122 A123 A129I74-K125 HydrophobicContact CD1-CB 4.1Å; I74-K125 HydrophobicContact CD1-CG 4.45Å; L121-K125 PolarHBondContact O-N 3.42Å; N122-K125 PolarHBondContact O-N 3.44Å; A123-K125 PolarHBondContact O-N 3.46Å; K125-A129 PolarHBondContact O-N 3.47Å; K125-A129 VanDerWaalsContact O-N 3.11Å
126R92.7Very high92.6Very high157 Ų15767.8 Ų67.859%0.59232%0.322SS*.Hα-helixtrans-64.6-41.6176.3-72.7-173.1-67.8-1011.4112.1N122 A123 A124 A129 K130N122-R126 WeakPolarHBondContact O-CG 3.32Å; N122-R126 PolarHBondContact O-N 2.98Å; N122-R126 VanDerWaalsContact O-N 3.08Å; A123-R126 PolarHBondContact O-N 3.17Å; A124-R126 VanDerWaalsContact C-N 3.34Å; A124-R126 PolarHBondContact O-N 3.42Å; R126-A129 PolarHBondContact O-N 3.1Å; R126-K130 PolarHBondContact O-N 3.38Å
127R94Very high92.6Very high107 Ų10768.5 Ų68.540%0.40432%0.324SS..Hα-helixtrans-60.9-45.4177.5-167.9-179.973.3-160.8-0.1111.5L111 G112 A123 A124 K130 Q131L111-R127 PolarHBondContact O-NH2 2.98Å; G112-R127 PolarHBondContact O-NH1 3.05Å; A123-R127 WeakPolarHBondContact O-CB 3.39Å; A123-R127 PolarHBondContact O-N 3.12Å; A124-R127 PolarHBondContact O-N 2.81Å; R127-K130 PolarHBondContact O-N 3.16Å; R127-Q131 WeakPolarHBondContact O-CG 3.45Å; R127-Q131 PolarHBondContact O-N 3.34Å
128L92.3Very high92.4Very high29 Ų2974.7 Ų74.715%0.15235%0.347CS..Hα-helixtrans-61.6-43.6176.1-71.5171.6000111.8N70 I74 L111 A124 K130 Q131 L132N70-L128 HydrophobicContact CB-CD1 4.13Å; I74-L128 HydrophobicContact CD1-CD1 4.16Å; L111-L128 HydrophobicContact CD2-CD1 3.96Å; A124-L128 WeakPolarHBondContact O-CG 3.45Å; A124-L128 PolarHBondContact O-N 3.14Å; L128-K130 VanDerWaalsContact C-N 3.35Å; L128-K130 PolarHBondContact O-N 3.4Å; L128-Q131 PolarHBondContact O-N 3.08Å; L128-L132 VanDerWaalsContact O-CG 3.31Å; L128-L132 WeakPolarHBondContact O-CG 3.39Å; L128-L132 PolarHBondContact O-N 2.9Å
129A91.1Very high92Very high29 Ų2972.8 Ų72.824%0.2434%0.342CS..Hα-helixtrans-60.2-44.6176.200000111.8K125 R126 L132 E133K125-A129 PolarHBondContact O-N 3.47Å; K125-A129 VanDerWaalsContact O-N 3.11Å; R126-A129 PolarHBondContact O-N 3.1Å; A129-L132 PolarHBondContact O-N 3.36Å; A129-E133 PolarHBondContact O-N 2.95Å
130K92.6Very high91.5Very high128 Ų12869.8 Ų69.856%0.55733%0.334SS*.Hα-helixtrans-63.6-42.1176.4-171.5179.3179.9-175.20112.5R126 R127 L128 L132 E133 E134R126-K130 PolarHBondContact O-N 3.38Å; R127-K130 PolarHBondContact O-N 3.16Å; L128-K130 VanDerWaalsContact C-N 3.35Å; L128-K130 PolarHBondContact O-N 3.4Å; K130-L132 VanDerWaalsContact C-N 3.34Å; K130-L132 PolarHBondContact O-N 3.31Å; K130-E133 WeakPolarHBondContact O-CB 3.41Å; K130-E133 PolarHBondContact O-N 3.41Å; K130-E134 WeakPolarHBondContact CE-OE1 3.16Å; K130-E134 WeakPolarHBondContact O-CG 3.5Å; K130-E134 PolarHBondContact O-N 3.26Å
131Q92.5Very high91Very high84 Ų8469.1 Ų69.139%0.39333%0.328SS..Hα-helixtrans-61.6-41.8176-76.3175.9-32.800112R127 L128 E133 E134 Q135R127-Q131 WeakPolarHBondContact O-CG 3.45Å; R127-Q131 PolarHBondContact O-N 3.34Å; L128-Q131 PolarHBondContact O-N 3.08Å; Q131-E133 VanDerWaalsContact C-N 3.34Å; Q131-E134 PolarHBondContact O-N 3.2Å; Q131-Q135 WeakPolarHBondContact O-CB 3.42Å; Q131-Q135 VanDerWaalsContact O-CG 3.23Å; Q131-Q135 WeakPolarHBondContact O-CG 3.22Å; Q131-Q135 PolarHBondContact O-N 2.76Å
132L90.6Very high90.7Very high30 Ų3068.9 Ų68.916%0.15733%0.327CS..Hα-helixtrans-63.7-41.7175.3-68.1171.9000111.3P52 H55 L128 A129 K130 Q135 L136P52-L132 HydrophobicContact CB-CB 4.3Å; P52-L132 HydrophobicContact CB-CD2 4.18Å; P52-L132 WeakPolarHBondContact CB-O 3Å; P52-L132 HydrophobicContact CG-CD2 4.03Å; H55-L132 HydrophobicContact CB-CD1 3.92Å; L128-L132 VanDerWaalsContact O-CG 3.31Å; L128-L132 WeakPolarHBondContact O-CG 3.39Å; L128-L132 PolarHBondContact O-N 2.9Å; A129-L132 PolarHBondContact O-N 3.36Å; K130-L132 VanDerWaalsContact C-N 3.34Å; K130-L132 PolarHBondContact O-N 3.31Å; L132-Q135 PolarHBondContact O-N 3.14Å; L132-L136 VanDerWaalsContact O-CB 3.32Å; L132-L136 WeakPolarHBondContact O-CB 3.5Å; L132-L136 PolarHBondContact O-N 3.29Å
133E91.4Very high90.3Very high39 Ų3973.4 Ų73.418%0.18234%0.337CS..Hα-helixtrans-59.4-50.7175.8-173.5-176.3154.500111.7L56 A129 K130 Q131 Q135 L136 H137 I149L56-E133 HydrophobicContact CD1-CB 3.9Å; A129-E133 PolarHBondContact O-N 2.95Å; K130-E133 WeakPolarHBondContact O-CB 3.41Å; K130-E133 PolarHBondContact O-N 3.41Å; Q131-E133 VanDerWaalsContact C-N 3.34Å; E133-Q135 PolarHBondContact O-N 3.08Å; E133-L136 WeakPolarHBondContact O-CB 3.22Å; E133-L136 PolarHBondContact O-N 3.47Å; E133-H137 WeakPolarHBondContact CG-CE1 3.44Å; E133-H137 VanDerWaalsContact O-CG 3.32Å; E133-H137 PolarHBondContact O-N 3.45Å; E133-H137 PolarHBondContact O-ND1 3.05Å; E133-H137 IonicContact OE1-CE1 2.59Å; E133-I149 VanDerWaalsContact OE1-CD1 3.3Å; E133-I149 WeakPolarHBondContact OE1-CD1 3.43Å
134E91.6Very high89.9Confident88 Ų8879.5 Ų79.541%0.41135%0.352SS..Hα-helixtrans-60.9-43.8177.7-71.6171.3-170.400112K130 Q131 L136 H137 K138K130-E134 WeakPolarHBondContact CE-OE1 3.16Å; K130-E134 WeakPolarHBondContact O-CG 3.5Å; K130-E134 PolarHBondContact O-N 3.26Å; Q131-E134 PolarHBondContact O-N 3.2Å; E134-L136 VanDerWaalsContact C-N 3.31Å; E134-L136 PolarHBondContact O-N 2.92Å; E134-H137 PolarHBondContact O-N 2.97Å; E134-K138 VanDerWaalsContact O-CG 3.32Å; E134-K138 WeakPolarHBondContact O-CG 3.31Å; E134-K138 PolarHBondContact O-N 3.46Å; E134-K138 VanDerWaalsContact O-N 3.14Å
135Q90.7Very high89.6Confident106 Ų10679.4 Ų79.450%0.49535%0.351SS..Hα-helixtrans-61-41.6175.5-76.8178-800111.6P52 Q131 L132 E133 T139P52-Q135 HydrophobicContact CG-CB 3.93Å; Q131-Q135 WeakPolarHBondContact O-CB 3.42Å; Q131-Q135 VanDerWaalsContact O-CG 3.23Å; Q131-Q135 WeakPolarHBondContact O-CG 3.22Å; Q131-Q135 PolarHBondContact O-N 2.76Å; L132-Q135 PolarHBondContact O-N 3.14Å; E133-Q135 PolarHBondContact O-N 3.08Å; Q135-T139 WeakPolarHBondContact O-CG2 3.22Å
136L90.3Very high89.4Confident2 Ų275 Ų751%0.0134%0.339CS..Hα-helixtrans-63.2-48.8178.5-178.258.2000111.1T50 P52 F53 L56 L132 E133 E134 K138 T139 G142 L145T50-L136 HydrophobicContact CG2-CD1 4.22Å; P52-L136 HydrophobicContact CB-CB 3.95Å; F53-L136 HydrophobicContact CB-CD1 3.83Å; F53-L136 HydrophobicContact CB-CD2 4.35Å; F53-L136 HydrophobicContact CD2-CD2 4.4Å; L56-L136 HydrophobicContact CD2-CD2 3.72Å; L132-L136 VanDerWaalsContact O-CB 3.32Å; L132-L136 WeakPolarHBondContact O-CB 3.5Å; L132-L136 PolarHBondContact O-N 3.29Å; E133-L136 WeakPolarHBondContact O-CB 3.22Å; E133-L136 PolarHBondContact O-N 3.47Å; E134-L136 VanDerWaalsContact C-N 3.31Å; E134-L136 PolarHBondContact O-N 2.92Å; L136-K138 VanDerWaalsContact C-N 3.29Å; L136-K138 PolarHBondContact O-N 2.99Å; L136-T139 WeakPolarHBondContact O-CB 3.09Å; L136-T139 PolarHBondContact O-N 3.49Å; L136-T139 PolarHBondContact O-OG1 3.27Å; L136-G142 VanDerWaalsContact O-CA 3.28Å; L136-G142 WeakPolarHBondContact O-CA 3.35Å; L136-L145 HydrophobicContact CD1-CD1 4.35Å; L136-L145 HydrophobicContact CD2-CD1 3.93Å; L136-L145 HydrophobicContact CG-CD1 4.34Å
137H89.7Confident89.2Confident39 Ų3975.4 Ų75.418%0.18135%0.345CS..Hα-helixtrans-69.3-24.6-175.5-62.7158.9000113.9E133 E134 T139 G142 R143E133-H137 WeakPolarHBondContact CG-CE1 3.44Å; E133-H137 VanDerWaalsContact O-CG 3.32Å; E133-H137 PolarHBondContact O-N 3.45Å; E133-H137 PolarHBondContact O-ND1 3.05Å; E133-H137 IonicContact OE1-CE1 2.59Å; E134-H137 PolarHBondContact O-N 2.97Å; H137-T139 PolarHBondContact O-N 2.74Å; H137-G142 PolarHBondContact CD2-O 2.67Å; H137-R143 WeakPolarHBondContact O-CA 3.33Å
138K89.1Confident89Confident176 Ų17672.8 Ų72.877%0.76534%0.337SS*.Hα-helixtrans-66.8-21169.7-74.1173.9-178.3-179.50113E134 L136E134-K138 VanDerWaalsContact O-CG 3.32Å; E134-K138 WeakPolarHBondContact O-CG 3.31Å; E134-K138 PolarHBondContact O-N 3.46Å; E134-K138 VanDerWaalsContact O-N 3.14Å; L136-K138 VanDerWaalsContact C-N 3.29Å; L136-K138 PolarHBondContact O-N 2.99Å
139T86.9Confident88.8Confident37 Ų3774.2 Ų74.223%0.22734%0.344CS..SBendtrans-86.3149.3179.971.80000112.6T50 Q135 L136 H137 Q141 G142 R143T50-T139 HydrophobicContact CG2-CG2 3.68Å; Q135-T139 WeakPolarHBondContact O-CG2 3.22Å; L136-T139 WeakPolarHBondContact O-CB 3.09Å; L136-T139 PolarHBondContact O-N 3.49Å; L136-T139 PolarHBondContact O-OG1 3.27Å; H137-T139 PolarHBondContact O-N 2.74Å; T139-Q141 PolarHBondContact O-N 3.45Å; T139-Q141 VanDerWaalsContact O-N 3.14Å; T139-G142 PolarHBondContact O-N 2.83Å; T139-G142 VanDerWaalsContact O-N 3.11Å; T139-G142 PolarHBondContact OG1-N 3.22Å; T139-G142 VanDerWaalsContact OG1-N 3.08Å; T139-R143 WeakPolarHBondContact O-CB 3.48Å; T139-R143 PolarHBondContact O-N 2.84Å
140N82.6Confident88.6Confident109 Ų10977.2 Ų77.258%0.58336%0.363SS*.THydrogen-bonded Turntrans-59.5-24.4173.3-75.3-33.3000113.9
141Q84.3Confident88.5Confident25 Ų2572.5 Ų72.512%0.11735%0.347CS..THydrogen-bonded Turntrans-78.9-38176.8-66.9171.224.800111.5T139 T176T139-Q141 PolarHBondContact O-N 3.45Å; T139-Q141 VanDerWaalsContact O-N 3.14Å; Q141-T176 WeakPolarHBondContact CB-O 3.34Å; Q141-T176 WeakPolarHBondContact CG-O 3.42Å
142G86.4Confident88.3Confident0 Ų076.5 Ų76.50%036%0.363CS..THydrogen-bonded Turntrans-95.9-13.8-176.400000115.5L136 H137 T139 R144 L145L136-G142 VanDerWaalsContact O-CA 3.28Å; L136-G142 WeakPolarHBondContact O-CA 3.35Å; H137-G142 PolarHBondContact CD2-O 2.67Å; T139-G142 PolarHBondContact O-N 2.83Å; T139-G142 VanDerWaalsContact O-N 3.11Å; T139-G142 PolarHBondContact OG1-N 3.22Å; T139-G142 VanDerWaalsContact OG1-N 3.08Å; G142-R144 PolarHBondContact O-N 2.91Å; G142-R144 VanDerWaalsContact O-N 3.13Å; G142-L145 WeakPolarHBondContact O-CA 3.39Å; G142-L145 VanDerWaalsContact O-CB 3.29Å; G142-L145 WeakPolarHBondContact O-CB 3.46Å; G142-L145 PolarHBondContact O-N 2.89Å
143R87.5Confident88.2Confident178 Ų17882.1 Ų82.167%0.67239%0.388SS*.G310 helixtrans-53.9-38.4-177-174.4174.8-179.2177.51.3113.4H137 T139 L145H137-R143 WeakPolarHBondContact O-CA 3.33Å; T139-R143 WeakPolarHBondContact O-CB 3.48Å; T139-R143 PolarHBondContact O-N 2.84Å; R143-L145 VanDerWaalsContact C-N 3.34Å
144R85Confident88Confident170 Ų17082.3 Ų82.364%0.64239%0.394SS*.G310 helixtrans-84.3-8177.8-55.5-171.686.8-172.57.5113.3G142 A146 F147G142-R144 PolarHBondContact O-N 2.91Å; G142-R144 VanDerWaalsContact O-N 3.13Å; R144-A146 VanDerWaalsContact C-N 3.26Å; R144-F147 WeakPolarHBondContact O-CD2 3.48Å
145L88.3Confident88Confident1 Ų178.3 Ų78.31%0.00538%0.375CS..G310 helixtrans-76.8-16.8176-62.3179.1000112.7F53 L136 G142 R143 F147 F148 R175F53-L145 HydrophobicContact CD2-CD1 3.56Å; F53-L145 HydrophobicContact CE2-CD1 3.86Å; L136-L145 HydrophobicContact CD1-CD1 4.35Å; L136-L145 HydrophobicContact CD2-CD1 3.93Å; L136-L145 HydrophobicContact CG-CD1 4.34Å; G142-L145 WeakPolarHBondContact O-CA 3.39Å; G142-L145 VanDerWaalsContact O-CB 3.29Å; G142-L145 WeakPolarHBondContact O-CB 3.46Å; G142-L145 PolarHBondContact O-N 2.89Å; R143-L145 VanDerWaalsContact C-N 3.34Å; L145-F147 PolarHBondContact O-N 3.01Å; L145-F147 VanDerWaalsContact O-N 3.15Å; L145-F148 HydrophobicContact CD2-CD2 3.83Å; L145-F148 HydrophobicContact CD2-CE2 4.12Å; L145-F148 WeakPolarHBondContact O-CB 3.29Å; L145-F148 PolarHBondContact O-N 3.47Å; L145-R175 HydrophobicContact CD2-CB 3.95Å; L145-R175 WeakPolarHBondContact CD2-O 3.39Å
146A88.9Confident88Confident40 Ų4075.2 Ų75.233%0.33137%0.368SS..G310 helixtrans-56.1-30.2173.900000112.7R144 F148 I149R144-A146 VanDerWaalsContact C-N 3.26Å; A146-F148 PolarHBondContact O-N 3.45Å; A146-I149 HydrophobicContact CB-CD1 4.24Å; A146-I149 VanDerWaalsContact O-CD1 3.27Å; A146-I149 WeakPolarHBondContact O-CD1 3.47Å; A146-I149 VanDerWaalsContact O-CG1 3.26Å; A146-I149 WeakPolarHBondContact O-CG1 3.45Å; A146-I149 PolarHBondContact O-N 3.28Å
147F88.6Confident87.9Confident167 Ų16776.1 Ų76.173%0.73237%0.374SS*.G310 helixtrans-67.5-15.3175.4-64.9-72000114R144 L145R144-F147 WeakPolarHBondContact O-CD2 3.48Å; L145-F147 PolarHBondContact O-N 3.01Å; L145-F147 VanDerWaalsContact O-N 3.15Å
148F88.2Confident88Confident52 Ų5274.4 Ų74.423%0.22837%0.366CS..G310 helixtrans-100.72.9-179.9-59.8-61.9000113.4L145 A146 S150 S151 N155 R175L145-F148 HydrophobicContact CD2-CD2 3.83Å; L145-F148 HydrophobicContact CD2-CE2 4.12Å; L145-F148 WeakPolarHBondContact O-CB 3.29Å; L145-F148 PolarHBondContact O-N 3.47Å; A146-F148 PolarHBondContact O-N 3.45Å; F148-S150 PolarHBondContact O-N 3.18Å; F148-S151 PolarHBondContact O-N 3.31Å; F148-N155 PolarHBondContact O-ND2 3.38Å; F148-R175 HydrophobicContact CE2-CG 4.42Å
149I88.8Confident87.9Confident59 Ų5969.5 Ų69.530%0.30335%0.351SS..THydrogen-bonded Turntrans-59.8127.7176.7-59.8161.1000108.7E133 A146 S151E133-I149 VanDerWaalsContact OE1-CD1 3.3Å; E133-I149 WeakPolarHBondContact OE1-CD1 3.43Å; A146-I149 HydrophobicContact CB-CD1 4.24Å; A146-I149 VanDerWaalsContact O-CD1 3.27Å; A146-I149 WeakPolarHBondContact O-CD1 3.47Å; A146-I149 VanDerWaalsContact O-CG1 3.26Å; A146-I149 WeakPolarHBondContact O-CG1 3.45Å; A146-I149 PolarHBondContact O-N 3.28Å; I149-S151 PolarHBondContact O-N 3.23Å
150S86.9Confident87.8Confident92 Ų9268.9 Ų68.964%0.64335%0.352SS*.THydrogen-bonded Turntrans60.89176.4-55.50000115.7Q59 F148 K152Q59-S150 WeakPolarHBondContact O-CA 3.28Å; Q59-S150 PolarHBondContact O-N 2.87Å; F148-S150 PolarHBondContact O-N 3.18Å; S150-K152 PolarHBondContact O-N 2.88Å
151S90.3Very high87.9Confident29 Ų2972.7 Ų72.720%0.20336%0.358CS..  trans-84.799.1174.7-179.40000110.3F148 I149 S154 N155F148-S151 PolarHBondContact O-N 3.31Å; I149-S151 PolarHBondContact O-N 3.23Å; S151-S154 WeakPolarHBondContact OG-CB 3.44Å; S151-S154 PolarHBondContact OG-N 3.23Å; S151-S154 PolarHBondContact OG-OG 3.4Å; S151-N155 VanDerWaalsContact O-CB 3.23Å; S151-N155 WeakPolarHBondContact O-CB 3.44Å; S151-N155 VanDerWaalsContact O-CG 3.24Å; S151-N155 PolarHBondContact O-N 3.43Å; S151-N155 PolarHBondContact O-ND2 3.11Å; S151-N155 VanDerWaalsContact O-ND2 3.14Å
152K88.9Confident87.9Confident167 Ų16777.7 Ų77.773%0.72639%0.385SS*.Hα-helixtrans-62.2-44.9-177.8-175.8-177.1177.2-1740111.7S150 N155 A156S150-K152 PolarHBondContact O-N 2.88Å; K152-N155 PolarHBondContact O-N 3.25Å; K152-A156 WeakPolarHBondContact O-CB 3.36Å; K152-A156 PolarHBondContact O-N 2.86Å
153E87.7Confident88.1Confident148 Ų14880.6 Ų80.669%0.69240%0.399SS*.Hα-helixtrans-65.7-47.9-176.5-58.669.6-150.300110N155 A156E153-N155 VanDerWaalsContact C-N 3.31Å; E153-N155 PolarHBondContact O-N 3.38Å; E153-A156 PolarHBondContact O-N 2.92Å
154S87.2Confident88.3Confident43 Ų4376.6 Ų76.630%0.30140%0.395SS..Hα-helixtrans-63-41.3176.1-60.70000110.6S151 C157 R175S151-S154 WeakPolarHBondContact OG-CB 3.44Å; S151-S154 PolarHBondContact OG-N 3.23Å; S151-S154 PolarHBondContact OG-OG 3.4Å; S154-C157 PolarHBondContact O-SG 2.92Å; S154-R175 PolarHBondContact O-NH2 3.01Å
155N92.2Very high88.6Confident5 Ų571 Ų713%0.02739%0.39CS..Hα-helixtrans-84.2-10.5-174.2-67.7-27000114.8T58 Q59 G61 F148 S151 K152 E153 C157 L158 R175T58-N155 HydrophobicContact CG2-CB 4.48Å; T58-N155 VanDerWaalsContact O-CB 3.27Å; T58-N155 WeakPolarHBondContact O-CB 3.48Å; T58-N155 PolarHBondContact O-ND2 2.92Å; Q59-N155 PolarHBondContact O-ND2 2.99Å; Q59-N155 VanDerWaalsContact O-ND2 3.14Å; G61-N155 PolarHBondContact N-ND2 3.23Å; F148-N155 PolarHBondContact O-ND2 3.38Å; S151-N155 VanDerWaalsContact O-CB 3.23Å; S151-N155 WeakPolarHBondContact O-CB 3.44Å; S151-N155 VanDerWaalsContact O-CG 3.24Å; S151-N155 PolarHBondContact O-N 3.43Å; S151-N155 PolarHBondContact O-ND2 3.11Å; S151-N155 VanDerWaalsContact O-ND2 3.14Å; K152-N155 PolarHBondContact O-N 3.25Å; E153-N155 VanDerWaalsContact C-N 3.31Å; E153-N155 PolarHBondContact O-N 3.38Å; N155-C157 PolarHBondContact O-N 3.21Å; N155-C157 VanDerWaalsContact O-N 3.14Å; N155-L158 HydrophobicContact CB-CD1 4.12Å; N155-L158 VanDerWaalsContact O-CB 3.31Å; N155-L158 WeakPolarHBondContact O-CB 3.25Å; N155-L158 PolarHBondContact O-N 2.59Å; N155-R175 PolarHBondContact OD1-NH1 3.17Å; N155-R175 VanDerWaalsContact OD1-NH1 3.13Å
156A90.3Very high88.8Confident41 Ų4176.7 Ų76.734%0.33942%0.416SS..G310 helixtrans-55.1-34.6178.300000112.6K152 E153 L158 V159 L162K152-A156 WeakPolarHBondContact O-CB 3.36Å; K152-A156 PolarHBondContact O-N 2.86Å; E153-A156 PolarHBondContact O-N 2.92Å; A156-L158 VanDerWaalsContact C-N 3.25Å; A156-L158 PolarHBondContact O-N 3.25Å; A156-V159 PolarHBondContact O-N 3.27Å; A156-L162 HydrophobicContact CB-CD1 4.16Å
157C88.9Confident89Confident20 Ų2076.6 Ų76.614%0.13542%0.415CS..G310 helixtrans-68.5-18.5179.161.80000114.6S154 N155 V159 G160 M163 L171 R175S154-C157 PolarHBondContact O-SG 2.92Å; N155-C157 PolarHBondContact O-N 3.21Å; N155-C157 VanDerWaalsContact O-N 3.14Å; C157-V159 PolarHBondContact O-N 3.3Å; C157-G160 PolarHBondContact O-N 3.27Å; C157-G160 VanDerWaalsContact O-N 3.08Å; C157-M163 HydrophobicContact CB-CE 3.56Å; C157-L171 HydrophobicContact CB-CD2 3.72Å; C157-L171 WeakPolarHBondContact SG-CD2 3.49Å; C157-R175 PolarHBondContact SG-NH2 3.26Å
158L91.2Very high89.2Confident3 Ų369.7 Ų69.72%0.01639%0.385CS..G310 helixtrans-72.2-14.8179.5-66175.8000113.4T58 G62 N155 A156 G160 I172 R175T58-L158 HydrophobicContact CG2-CB 3.58Å; T58-L158 HydrophobicContact CG2-CD1 3.96Å; T58-L158 HydrophobicContact CG2-CG 4.4Å; G62-L158 WeakPolarHBondContact O-CD1 3.36Å; N155-L158 HydrophobicContact CB-CD1 4.12Å; N155-L158 VanDerWaalsContact O-CB 3.31Å; N155-L158 WeakPolarHBondContact O-CB 3.25Å; N155-L158 PolarHBondContact O-N 2.59Å; A156-L158 VanDerWaalsContact C-N 3.25Å; A156-L158 PolarHBondContact O-N 3.25Å; L158-G160 PolarHBondContact O-N 3Å; L158-I172 HydrophobicContact CD2-CD1 3.59Å; L158-R175 VanDerWaalsContact CD1-NH1 3.33Å; L158-R175 VanDerWaalsContact CG-NH1 3.28Å
159V87.4Confident89.5Confident73 Ų7368.6 Ų68.644%0.44238%0.381SS..G310 helixtrans-71-21.7171.2-174.10000110.9A156 C157 R161A156-V159 PolarHBondContact O-N 3.27Å; C157-V159 PolarHBondContact O-N 3.3Å; V159-R161 VanDerWaalsContact C-N 3.3Å; V159-R161 HydrophobicContact CG1-CG 4.05Å; V159-R161 PolarHBondContact O-N 2.98Å
160G84.1Confident89.7Confident25 Ų2570.7 Ų70.726%0.25839%0.386SS..SBendtrans78.55.5175.700000115.4C157 L158C157-G160 PolarHBondContact O-N 3.27Å; C157-G160 VanDerWaalsContact O-N 3.08Å; L158-G160 PolarHBondContact O-N 3Å
161R85.1Confident89.9Confident189 Ų18967.9 Ų67.971%0.71336%0.363SS*.  trans-85.9-13.7179.7-66.2178.6-173.5-168.60.8114.3E7 V159E7-R161 IonicContact OE1-NH2 3.58Å; E7-R161 PolarHBondContact OE1-NH2 2.82Å; E7-R161 VanDerWaalsContact OE1-NH2 3.1Å; V159-R161 VanDerWaalsContact C-N 3.3Å; V159-R161 HydrophobicContact CG1-CG 4.05Å; V159-R161 PolarHBondContact O-N 2.98Å
162L84.4Confident90Very high129 Ų12966.5 Ų66.568%0.67535%0.353SS*.SBendtrans-93.41.1-174.3-59.5179.2000114A156A156-L162 HydrophobicContact CB-CD1 4.16Å
163M89.4Confident90.1Very high61 Ų6159 Ų5930%0.332%0.321SS..SBendtrans-158.9167.5-172.865.6-170.665.400112.7C157 A167 F168 L171C157-M163 HydrophobicContact CB-CE 3.56Å; M163-A167 HydrophobicContact CB-CB 3.86Å; M163-A167 HydrophobicContact CG-CB 4.03Å; M163-A167 VanDerWaalsContact SD-C 3.55Å; M163-A167 HydrophobicContact SD-CB 4Å; M163-F168 HydrophobicContact CG-CB 4.07Å; M163-F168 VanDerWaalsContact SD-CA 3.54Å; M163-F168 HydrophobicContact SD-CB 4.14Å; M163-F168 HydrophobicContact SD-CD2 4.5Å; M163-F168 PolarHBondContact SD-N 2.79Å; M163-F168 VanDerWaalsContact SD-N 3.44Å; M163-L171 HydrophobicContact CE-CD2 3.91Å; M163-L171 HydrophobicContact SD-CB 4.23Å; M163-L171 HydrophobicContact SD-CD2 3.94Å
164T92.3Very high90.3Very high95 Ų9556 Ų5658%0.58331%0.309SS*.  trans-65.2158.6174.268.80000111.7H166 A167 F168T164-H166 VanDerWaalsContact C-N 3.25Å; T164-H166 PolarHBondContact O-N 2.83Å; T164-A167 PolarHBondContact O-N 3.36Å; T164-A167 VanDerWaalsContact O-N 3.16Å; T164-A167 WeakPolarHBondContact OG1-CB 3.39Å; T164-A167 PolarHBondContact OG1-N 2.68Å; T164-F168 PolarHBondContact O-N 3.41Å
165G91.5Very high90.4Very high52 Ų5255.2 Ų55.254%0.53630%0.299SS..Hα-helixtrans-57.3-37.7176.700000113.3F168 I169G165-F168 WeakPolarHBondContact O-CB 3.44Å; G165-F168 PolarHBondContact O-N 3.2Å; G165-I169 WeakPolarHBondContact O-CD1 3.25Å; G165-I169 WeakPolarHBondContact O-CG1 3.3Å; G165-I169 PolarHBondContact O-N 3.13Å
166H92.6Very high90.3Very high120 Ų12055.1 Ų55.156%0.55630%0.299SS*.Hα-helixtrans-64-47.8175.3-175.888.5000111.9T164 F168 I169 R170T164-H166 VanDerWaalsContact C-N 3.25Å; T164-H166 PolarHBondContact O-N 2.83Å; H166-F168 VanDerWaalsContact C-N 3.26Å; H166-F168 PolarHBondContact O-N 3.43Å; H166-I169 PolarHBondContact O-N 3.38Å; H166-R170 WeakPolarHBondContact O-CG 3.48Å; H166-R170 PolarHBondContact O-N 2.99Å
167A92.9Very high90.2Very high38 Ų3855.4 Ų55.431%0.31430%0.295SS..Hα-helixtrans-61.4-38.3177.200000111.3M163 T164 R170 L171M163-A167 HydrophobicContact CB-CB 3.86Å; M163-A167 HydrophobicContact CG-CB 4.03Å; M163-A167 VanDerWaalsContact SD-C 3.55Å; M163-A167 HydrophobicContact SD-CB 4Å; T164-A167 PolarHBondContact O-N 3.36Å; T164-A167 VanDerWaalsContact O-N 3.16Å; T164-A167 WeakPolarHBondContact OG1-CB 3.39Å; T164-A167 PolarHBondContact OG1-N 2.68Å; A167-R170 PolarHBondContact O-N 3.15Å; A167-L171 WeakPolarHBondContact O-CB 3.37Å; A167-L171 PolarHBondContact O-N 3Å
168F93.6Very high90.1Very high22 Ų2254.7 Ų54.710%0.09629%0.29CS..Hα-helixtrans-62-47.1174.9-176.8-103.9000112I2 L42 L63 M163 T164 G165 H166 R170 L171 I172I2-F168 HydrophobicContact CD1-CD1 4.5Å; I2-F168 HydrophobicContact CD1-CE1 3.79Å; L42-F168 HydrophobicContact CD2-CD1 4.15Å; L42-F168 HydrophobicContact CD2-CE1 3.9Å; L63-F168 HydrophobicContact CD1-CZ 4Å; M163-F168 HydrophobicContact CG-CB 4.07Å; M163-F168 VanDerWaalsContact SD-CA 3.54Å; M163-F168 HydrophobicContact SD-CB 4.14Å; M163-F168 HydrophobicContact SD-CD2 4.5Å; M163-F168 PolarHBondContact SD-N 2.79Å; M163-F168 VanDerWaalsContact SD-N 3.44Å; T164-F168 PolarHBondContact O-N 3.41Å; G165-F168 WeakPolarHBondContact O-CB 3.44Å; G165-F168 PolarHBondContact O-N 3.2Å; H166-F168 VanDerWaalsContact C-N 3.26Å; H166-F168 PolarHBondContact O-N 3.43Å; F168-R170 VanDerWaalsContact C-N 3.35Å; F168-R170 PolarHBondContact O-N 3.29Å; F168-L171 WeakPolarHBondContact O-CB 3.24Å; F168-L171 PolarHBondContact O-N 3.21Å; F168-I172 HydrophobicContact CD1-CG1 4.47Å; F168-I172 HydrophobicContact CE1-CG1 4.11Å; F168-I172 HydrophobicContact CE2-CD1 4.29Å; F168-I172 HydrophobicContact CE2-CG1 4.43Å; F168-I172 HydrophobicContact CZ-CD1 4.11Å; F168-I172 HydrophobicContact CZ-CG1 4.1Å; F168-I172 WeakPolarHBondContact O-CG1 3.43Å; F168-I172 PolarHBondContact O-N 2.99Å
169I93.3Very high90.1Very high29 Ų2955.9 Ų55.915%0.14930%0.298CS..Hα-helixtrans-57.5-48.4175.4-72.7159.9000110.9L42 G165 H166 L171 I172 Q173L42-I169 HydrophobicContact CD2-CG1 4.24Å; L42-I169 WeakPolarHBondContact O-CG2 3.31Å; G165-I169 WeakPolarHBondContact O-CD1 3.25Å; G165-I169 WeakPolarHBondContact O-CG1 3.3Å; G165-I169 PolarHBondContact O-N 3.13Å; H166-I169 PolarHBondContact O-N 3.38Å; I169-L171 PolarHBondContact O-N 3.35Å; I169-I172 PolarHBondContact O-N 3.44Å; I169-Q173 HydrophobicContact CG2-CG 4.48Å; I169-Q173 WeakPolarHBondContact O-CG 3.32Å; I169-Q173 PolarHBondContact O-N 3.13Å
170R93.1Very high90.2Very high104 Ų10455.3 Ų55.339%0.39230%0.295SS..Hα-helixtrans-63.9-39.5179.4-68.6-55.7-169.5-175.65112.6H166 A167 F168 Q173 L174H166-R170 WeakPolarHBondContact O-CG 3.48Å; H166-R170 PolarHBondContact O-N 2.99Å; A167-R170 PolarHBondContact O-N 3.15Å; F168-R170 VanDerWaalsContact C-N 3.35Å; F168-R170 PolarHBondContact O-N 3.29Å; R170-Q173 PolarHBondContact O-N 3.28Å; R170-L174 WeakPolarHBondContact O-CB 3.36Å; R170-L174 VanDerWaalsContact O-CG 3.25Å; R170-L174 WeakPolarHBondContact O-CG 3.25Å; R170-L174 PolarHBondContact O-N 3.45Å
171L92.4Very high90.5Very high33 Ų3354.3 Ų54.317%0.17328%0.284CS..Hα-helixtrans-57.2-49.9173.5168.872.1000111C157 M163 A167 F168 I169 Q173 L174 R175C157-L171 HydrophobicContact CB-CD2 3.72Å; C157-L171 WeakPolarHBondContact SG-CD2 3.49Å; M163-L171 HydrophobicContact CE-CD2 3.91Å; M163-L171 HydrophobicContact SD-CB 4.23Å; M163-L171 HydrophobicContact SD-CD2 3.94Å; A167-L171 WeakPolarHBondContact O-CB 3.37Å; A167-L171 PolarHBondContact O-N 3Å; F168-L171 WeakPolarHBondContact O-CB 3.24Å; F168-L171 PolarHBondContact O-N 3.21Å; I169-L171 PolarHBondContact O-N 3.35Å; L171-Q173 VanDerWaalsContact C-N 3.35Å; L171-L174 PolarHBondContact O-N 3.27Å; L171-R175 HydrophobicContact CD1-CG 4.32Å; L171-R175 WeakPolarHBondContact O-CB 3.47Å; L171-R175 WeakPolarHBondContact O-CG 3.39Å; L171-R175 PolarHBondContact O-N 2.89Å
172I92Very high90.8Very high0 Ų048.9 Ų48.90%026%0.264CS..Hα-helixtrans-61.2-47.6179-61.1-58.8000109.7L42 L44 F53 L63 L158 F168 I169 L174 R175 T176L42-I172 HydrophobicContact CD1-CG2 4.32Å; L42-I172 HydrophobicContact CD2-CG1 4.28Å; L44-I172 HydrophobicContact CD1-CG2 3.91Å; F53-I172 HydrophobicContact CE1-CG2 3.91Å; F53-I172 HydrophobicContact CZ-CD1 4.24Å; F53-I172 HydrophobicContact CZ-CG2 4.16Å; L63-I172 HydrophobicContact CD1-CD1 4.08Å; L158-I172 HydrophobicContact CD2-CD1 3.59Å; F168-I172 HydrophobicContact CD1-CG1 4.47Å; F168-I172 HydrophobicContact CE1-CG1 4.11Å; F168-I172 HydrophobicContact CE2-CD1 4.29Å; F168-I172 HydrophobicContact CE2-CG1 4.43Å; F168-I172 HydrophobicContact CZ-CD1 4.11Å; F168-I172 HydrophobicContact CZ-CG1 4.1Å; F168-I172 WeakPolarHBondContact O-CG1 3.43Å; F168-I172 PolarHBondContact O-N 2.99Å; I169-I172 PolarHBondContact O-N 3.44Å; I172-L174 VanDerWaalsContact C-N 3.31Å; I172-L174 PolarHBondContact O-N 3.37Å; I172-R175 PolarHBondContact O-N 3.34Å; I172-R175 VanDerWaalsContact O-N 3.12Å; I172-T176 HydrophobicContact CG2-CG2 4.36Å; I172-T176 PolarHBondContact O-N 2.81Å; I172-T176 PolarHBondContact O-OG1 3.36Å
173Q91.6Very high90.9Very high8 Ų845 Ų454%0.03724%0.243CC..Hα-helixtrans-58.1-40.9178.6-72.9175.4-10.600113.3H43 L44 I169 R170 L171 N177 T178 V179H43-Q173 PolarHBondContact O-NE2 3.37Å; H43-Q173 VanDerWaalsContact O-NE2 3.1Å; L44-Q173 HydrophobicContact CD2-CG 3.77Å; I169-Q173 HydrophobicContact CG2-CG 4.48Å; I169-Q173 WeakPolarHBondContact O-CG 3.32Å; I169-Q173 PolarHBondContact O-N 3.13Å; R170-Q173 PolarHBondContact O-N 3.28Å; L171-Q173 VanDerWaalsContact C-N 3.35Å; Q173-N177 PolarHBondContact O-N 2.84Å; Q173-N177 VanDerWaalsContact O-N 3.15Å; Q173-T178 WeakPolarHBondContact CA-OG1 3.45Å; Q173-T178 PolarHBondContact O-N 3.02Å; Q173-T178 PolarHBondContact O-OG1 3.27Å; Q173-V179 HydrophobicContact CB-CG2 3.96Å; Q173-V179 PolarHBondContact O-N 2.89Å
174L90.8Very high90.8Very high85 Ų8542.9 Ų42.945%0.44524%0.235SC..Hα-helixtrans-64.7-44.4175.9-76.5166.1000111.5R170 L171 I172 N177 V179 L212R170-L174 WeakPolarHBondContact O-CB 3.36Å; R170-L174 VanDerWaalsContact O-CG 3.25Å; R170-L174 WeakPolarHBondContact O-CG 3.25Å; R170-L174 PolarHBondContact O-N 3.45Å; L171-L174 PolarHBondContact O-N 3.27Å; I172-L174 VanDerWaalsContact C-N 3.31Å; I172-L174 PolarHBondContact O-N 3.37Å; L174-N177 PolarHBondContact O-N 3.36Å; L174-V179 HydrophobicContact CD2-CG2 3.79Å; L174-V179 HydrophobicContact CG-CG2 4.01Å; L174-L212 HydrophobicContact CD2-CD1 3.69Å; L174-L212 HydrophobicContact CD2-CD2 4.15Å; L174-L212 HydrophobicContact CD2-CG 4.46Å
175R89.5Confident90.5Very high27 Ų2743.1 Ų43.110%0.10223%0.232CC..Hα-helixtrans-65.7-44.4-179.8-79.7-172.3171.7-154.6-6112.7L145 F148 S154 N155 C157 L158 L171 I172 N177L145-R175 HydrophobicContact CD2-CB 3.95Å; L145-R175 WeakPolarHBondContact CD2-O 3.39Å; F148-R175 HydrophobicContact CE2-CG 4.42Å; S154-R175 PolarHBondContact O-NH2 3.01Å; N155-R175 PolarHBondContact OD1-NH1 3.17Å; N155-R175 VanDerWaalsContact OD1-NH1 3.13Å; C157-R175 PolarHBondContact SG-NH2 3.26Å; L158-R175 VanDerWaalsContact CD1-NH1 3.33Å; L158-R175 VanDerWaalsContact CG-NH1 3.28Å; L171-R175 HydrophobicContact CD1-CG 4.32Å; L171-R175 WeakPolarHBondContact O-CB 3.47Å; L171-R175 WeakPolarHBondContact O-CG 3.39Å; L171-R175 PolarHBondContact O-N 2.89Å; I172-R175 PolarHBondContact O-N 3.34Å; I172-R175 VanDerWaalsContact O-N 3.12Å; R175-N177 VanDerWaalsContact C-N 3.27Å; R175-N177 PolarHBondContact O-N 3.37Å
176T89.2Confident90.2Very high3 Ų342.4 Ų42.42%0.01822%0.216CC..THydrogen-bonded Turntrans-85.53.3-178.255.10000113.3F53 Q141 I172 T178F53-T176 HydrophobicContact CD1-CG2 3.81Å; F53-T176 HydrophobicContact CD2-CG2 3.96Å; F53-T176 HydrophobicContact CE1-CG2 3.65Å; F53-T176 HydrophobicContact CE2-CG2 3.8Å; F53-T176 HydrophobicContact CG-CG2 3.96Å; F53-T176 HydrophobicContact CZ-CG2 3.64Å; Q141-T176 WeakPolarHBondContact CB-O 3.34Å; Q141-T176 WeakPolarHBondContact CG-O 3.42Å; I172-T176 HydrophobicContact CG2-CG2 4.36Å; I172-T176 PolarHBondContact O-N 2.81Å; I172-T176 PolarHBondContact O-OG1 3.36Å; T176-T178 VanDerWaalsContact C-N 3.27Å; T176-T178 WeakPolarHBondContact O-CG2 3.41Å; T176-T178 PolarHBondContact O-N 2.94Å; T176-T178 PolarHBondContact OG1-OG1 2.96Å
177N88.2Confident89.5Confident47 Ų4741.5 Ų41.525%0.25121%0.207SC..THydrogen-bonded Turntrans54.942.5-176.5-167.631.1000112.6Q173 L174 R175Q173-N177 PolarHBondContact O-N 2.84Å; Q173-N177 VanDerWaalsContact O-N 3.15Å; L174-N177 PolarHBondContact O-N 3.36Å; R175-N177 VanDerWaalsContact C-N 3.27Å; R175-N177 PolarHBondContact O-N 3.37Å
178T88.5Confident88.7Confident5 Ų543.2 Ų43.23%0.03123%0.229CC..  trans-118.312.3-178.757.50000112.9L44 A48 Q173 T176L44-T178 HydrophobicContact CD2-CG2 4.36Å; L44-T178 WeakPolarHBondContact CD2-OG1 3.41Å; A48-T178 HydrophobicContact CB-CG2 3.52Å; Q173-T178 WeakPolarHBondContact CA-OG1 3.45Å; Q173-T178 PolarHBondContact O-N 3.02Å; Q173-T178 PolarHBondContact O-OG1 3.27Å; T176-T178 VanDerWaalsContact C-N 3.27Å; T176-T178 WeakPolarHBondContact O-CG2 3.41Å; T176-T178 PolarHBondContact O-N 2.94Å; T176-T178 PolarHBondContact OG1-OG1 2.96Å
179V90.4Very high87.9Confident29 Ų2944.6 Ų44.618%0.17624%0.241CC..SBendtrans-52.5135.51641780000108Q173 L174 T181 A184 L212Q173-V179 HydrophobicContact CB-CG2 3.96Å; Q173-V179 PolarHBondContact O-N 2.89Å; L174-V179 HydrophobicContact CD2-CG2 3.79Å; L174-V179 HydrophobicContact CG-CG2 4.01Å; V179-T181 HydrophobicContact CB-CG2 4.46Å; V179-T181 HydrophobicContact CG1-CG2 4.14Å; V179-T181 PolarHBondContact O-N 3.25Å; V179-A184 WeakPolarHBondContact O-CB 3.5Å; V179-L212 HydrophobicContact CB-CD1 4.02Å; V179-L212 HydrophobicContact CG1-CD1 4.25Å; V179-L212 HydrophobicContact CG2-CD1 3.86Å; V179-L212 HydrophobicContact CG2-CD2 4.5Å
180P89.6Confident86.4Confident60 Ų6052 Ų5239%0.3928%0.28SS..  trans-74.759.5-171.831.9-38.6000113.1L185P180-L185 HydrophobicContact CB-CD1 4.34Å; P180-L185 HydrophobicContact CB-CD2 4.26Å; P180-L185 HydrophobicContact CB-CG 4.41Å
181T90.8Very high85.1Confident5 Ų553.4 Ų53.43%0.03129%0.289CS..  trans-78.3155.7168.778.60000109.7V179 M183 A184 L185 E210V179-T181 HydrophobicContact CB-CG2 4.46Å; V179-T181 HydrophobicContact CG1-CG2 4.14Å; V179-T181 PolarHBondContact O-N 3.25Å; T181-M183 PolarHBondContact O-N 3.41Å; T181-A184 WeakPolarHBondContact O-CA 3.09Å; T181-A184 WeakPolarHBondContact O-CB 3.48Å; T181-A184 PolarHBondContact O-N 3.2Å; T181-A184 PolarHBondContact OG1-N 3Å; T181-L185 WeakPolarHBondContact O-CG 3.44Å; T181-L185 PolarHBondContact O-N 3.25Å; T181-E210 WeakPolarHBondContact CB-O 3.33Å; T181-E210 PolarHBondContact OG1-O 3.08Å
182R89.9Confident83.8Confident74 Ų7456 Ų5628%0.27930%0.303SS..Hα-helixtrans-52.4-40.3176-79159.5168.2-163.72.4112.6A184 L185 L186 Q196 K198 R200 E210R182-A184 VanDerWaalsContact C-N 3.31Å; R182-A184 PolarHBondContact O-N 3.16Å; R182-L185 PolarHBondContact O-N 2.97Å; R182-L186 HydrophobicContact CB-CD1 4.44Å; R182-L186 VanDerWaalsContact O-CB 3.31Å; R182-L186 WeakPolarHBondContact O-CB 3.46Å; R182-L186 WeakPolarHBondContact O-CG 3.45Å; R182-L186 PolarHBondContact O-N 3.12Å; R182-Q196 WeakPolarHBondContact CB-O 3.4Å; R182-Q196 WeakPolarHBondContact CD-O 3.36Å; R182-Q196 VanDerWaalsContact CG-O 3.25Å; R182-Q196 WeakPolarHBondContact CG-O 3.4Å; R182-K198 WeakPolarHBondContact CD-O 3.4Å; R182-K198 PolarHBondContact NH1-O 2.9Å; R182-R200 VanDerWaalsContact NE-CG 3.32Å; R182-E210 HydrophobicContact CB-CB 3.9Å; R182-E210 VanDerWaalsContact CB-OE2 3.31Å; R182-E210 WeakPolarHBondContact CB-OE2 3.46Å; R182-E210 WeakPolarHBondContact CD-OE2 3.27Å; R182-E210 WeakPolarHBondContact CG-OE2 3.44Å; R182-E210 PolarHBondContact N-OE2 3.35Å
183M88.1Confident82.6Confident48 Ų4860.7 Ų60.724%0.23634%0.341CS..Hα-helixtrans-65.6-30.1176.1-68.4-66.5-67.200114T181 L192 T197 F209 E210 T211T181-M183 PolarHBondContact O-N 3.41Å; M183-L192 HydrophobicContact CE-CD2 3.6Å; M183-L192 HydrophobicContact SD-CD2 4.25Å; M183-T197 HydrophobicContact SD-CG2 3.96Å; M183-F209 HydrophobicContact CG-CB 4.17Å; M183-F209 HydrophobicContact SD-CB 4.12Å; M183-F209 HydrophobicContact SD-CG 4.45Å; M183-E210 VanDerWaalsContact CB-O 3.25Å; M183-E210 WeakPolarHBondContact CB-O 3.01Å; M183-E210 WeakPolarHBondContact CG-O 3.34Å; M183-E210 PolarHBondContact N-O 2.97Å; M183-T211 HydrophobicContact CB-CG2 4.29Å; M183-T211 HydrophobicContact CG-CG2 3.8Å
184A86.5Confident81.9Confident16 Ų1661.9 Ų61.913%0.13235%0.35CS..Hα-helixtrans-77.2-38.9175.300000111.8V179 T181 R182 R187V179-A184 WeakPolarHBondContact O-CB 3.5Å; T181-A184 WeakPolarHBondContact O-CA 3.09Å; T181-A184 WeakPolarHBondContact O-CB 3.48Å; T181-A184 PolarHBondContact O-N 3.2Å; T181-A184 PolarHBondContact OG1-N 3Å; R182-A184 VanDerWaalsContact C-N 3.31Å; R182-A184 PolarHBondContact O-N 3.16Å; A184-R187 WeakPolarHBondContact O-CB 3.5Å
185L86Confident81.4Confident100 Ų10062.6 Ų62.652%0.52435%0.351SS..Hα-helixtrans-74.3-39.5-178.8-66.8173.1000113P180 T181 R182 R187P180-L185 HydrophobicContact CB-CD1 4.34Å; P180-L185 HydrophobicContact CB-CD2 4.26Å; P180-L185 HydrophobicContact CB-CG 4.41Å; T181-L185 WeakPolarHBondContact O-CG 3.44Å; T181-L185 PolarHBondContact O-N 3.25Å; R182-L185 PolarHBondContact O-N 2.97Å; L185-R187 PolarHBondContact O-N 3.34Å
186L84.6Confident81.3Confident37 Ų3766 Ų6619%0.19437%0.369CS..THydrogen-bonded Turntrans-87.413.3179-62.7171000112.8R182 G188 S189 Q196 T197R182-L186 HydrophobicContact CB-CD1 4.44Å; R182-L186 VanDerWaalsContact O-CB 3.31Å; R182-L186 WeakPolarHBondContact O-CB 3.46Å; R182-L186 WeakPolarHBondContact O-CG 3.45Å; R182-L186 PolarHBondContact O-N 3.12Å; L186-G188 PolarHBondContact O-N 2.9Å; L186-S189 VanDerWaalsContact O-CB 3.31Å; L186-S189 WeakPolarHBondContact O-CB 3.35Å; L186-S189 PolarHBondContact O-N 2.91Å; L186-S189 PolarHBondContact O-OG 3.32Å; L186-Q196 HydrophobicContact CD1-CB 3.83Å; L186-Q196 VanDerWaalsContact CD1-O 3.27Å; L186-Q196 WeakPolarHBondContact CD1-O 3.49Å; L186-T197 HydrophobicContact CB-CG2 4.48Å; L186-T197 HydrophobicContact CD1-CG2 3.68Å
187R78.6Confident81.3Confident101 Ų10165.9 Ų65.938%0.38137%0.368SS..THydrogen-bonded Turntrans-63.8124.9-179.1-173.7-174.2-64-91.65.1109.8A184 L185 S189A184-R187 WeakPolarHBondContact O-CB 3.5Å; L185-R187 PolarHBondContact O-N 3.34Å; R187-S189 VanDerWaalsContact C-N 3.29Å
188G75.2Confident81.5Confident75 Ų7566.2 Ų66.277%0.77337%0.367SS*.THydrogen-bonded Turntrans86.5-5.6-177.500000113.9L186L186-G188 PolarHBondContact O-N 2.9Å
189S77.5Confident81.8Confident50 Ų5066.2 Ų66.235%0.3537%0.367SS..  trans-78.5136.9171.1-53.80000110.4L186 R187 K191L186-S189 VanDerWaalsContact O-CB 3.31Å; L186-S189 WeakPolarHBondContact O-CB 3.35Å; L186-S189 PolarHBondContact O-N 2.91Å; L186-S189 PolarHBondContact O-OG 3.32Å; R187-S189 VanDerWaalsContact C-N 3.29Å; S189-K191 PolarHBondContact O-N 2.89Å
190L62Low81.9Confident184 Ų18471 Ų7196%0.96338%0.382SS*.THydrogen-bonded Turntrans-61.6-13.5177.5-69.1164.2000113.8L192L190-L192 VanDerWaalsContact C-N 3.29Å; L190-L192 PolarHBondContact O-N 3.43Å
191K66.6Low82.1Confident135 Ų13573.8 Ų73.859%0.58739%0.39SS*.THydrogen-bonded Turntrans-88.628.6-175.3-59.2-175.2178.8-178.30114.2S189 A193 S194S189-K191 PolarHBondContact O-N 2.89Å; K191-A193 PolarHBondContact O-N 3.44Å; K191-A193 VanDerWaalsContact O-N 3.14Å; K191-S194 WeakPolarHBondContact O-CB 3.38Å; K191-S194 PolarHBondContact O-N 3.24Å; K191-S194 PolarHBondContact O-OG 3.23Å
192L63.3Low82.2Confident87 Ų8773.7 Ų73.746%0.45539%0.389SS..THydrogen-bonded Turntrans-59.6-25.4-174.3-109.1139.3000114.1M183 L190 T197M183-L192 HydrophobicContact CE-CD2 3.6Å; M183-L192 HydrophobicContact SD-CD2 4.25Å; L190-L192 VanDerWaalsContact C-N 3.29Å; L190-L192 PolarHBondContact O-N 3.43Å; L192-T197 WeakPolarHBondContact O-CB 3.35Å; L192-T197 WeakPolarHBondContact O-CG2 3.38Å; L192-T197 PolarHBondContact O-OG1 3.14Å
193A67.1Low82.4Confident98 Ų9870.2 Ų70.281%0.8138%0.376SS*.THydrogen-bonded Turntrans-96.89.3178.500000114.2K191K191-A193 PolarHBondContact O-N 3.44Å; K191-A193 VanDerWaalsContact O-N 3.14Å
194S77Confident82.5Confident33 Ų3372.5 Ų72.523%0.23140%0.397CS..SBendtrans-83.5163.3-178.667.20000113.1K191 Q196 T197K191-S194 WeakPolarHBondContact O-CB 3.38Å; K191-S194 PolarHBondContact O-N 3.24Å; K191-S194 PolarHBondContact O-OG 3.23Å; S194-Q196 PolarHBondContact O-N 3.19Å; S194-Q196 WeakPolarHBondContact OG-CB 3.4Å; S194-Q196 PolarHBondContact OG-N 3.24Å; S194-T197 PolarHBondContact O-N 3.11Å; S194-T197 PolarHBondContact O-OG1 3.44Å
195E82Confident82.7Confident100 Ų10077.2 Ų77.247%0.46742%0.42SS..G310 helixtrans-48.1-27.1169.3-168.961.3-153.200112.8T197 K198E195-T197 VanDerWaalsContact C-N 3.25Å; E195-T197 PolarHBondContact O-N 3.08Å; E195-K198 WeakPolarHBondContact O-CB 3.37Å; E195-K198 PolarHBondContact O-N 3.39Å; E195-K198 IonicContact OE1-NZ 3.8Å; E195-K198 WeakPolarHBondContact OE2-CD 3.39Å; E195-K198 WeakPolarHBondContact OE2-CE 3.46Å; E195-K198 IonicContact OE2-NZ 3.26Å; E195-K198 PolarHBondContact OE2-NZ 3.38Å
196Q86.5Confident83Confident100 Ų10075.5 Ų75.547%0.46741%0.414SS..G310 helixtrans-68.7-17.3-179.1-54.6-177.2-2000113.9R182 L186 S194R182-Q196 WeakPolarHBondContact CB-O 3.4Å; R182-Q196 WeakPolarHBondContact CD-O 3.36Å; R182-Q196 VanDerWaalsContact CG-O 3.25Å; R182-Q196 WeakPolarHBondContact CG-O 3.4Å; L186-Q196 HydrophobicContact CD1-CB 3.83Å; L186-Q196 VanDerWaalsContact CD1-O 3.27Å; L186-Q196 WeakPolarHBondContact CD1-O 3.49Å; S194-Q196 PolarHBondContact O-N 3.19Å; S194-Q196 WeakPolarHBondContact OG-CB 3.4Å; S194-Q196 PolarHBondContact OG-N 3.24Å
197T89.2Confident83.3Confident0 Ų075.6 Ų75.60%042%0.424CS..G310 helixtrans-93-13.1175.356.60000113.5M183 L186 L192 S194 E195 F209 E210M183-T197 HydrophobicContact SD-CG2 3.96Å; L186-T197 HydrophobicContact CB-CG2 4.48Å; L186-T197 HydrophobicContact CD1-CG2 3.68Å; L192-T197 WeakPolarHBondContact O-CB 3.35Å; L192-T197 WeakPolarHBondContact O-CG2 3.38Å; L192-T197 PolarHBondContact O-OG1 3.14Å; S194-T197 PolarHBondContact O-N 3.11Å; S194-T197 PolarHBondContact O-OG1 3.44Å; E195-T197 VanDerWaalsContact C-N 3.25Å; E195-T197 PolarHBondContact O-N 3.08Å; T197-F209 CarbonylContact O-C 3.53Å; T197-F209 WeakPolarHBondContact O-CA 3.25Å; T197-F209 VanDerWaalsContact OG1-CD1 3.24Å; T197-F209 WeakPolarHBondContact OG1-CD1 3.38Å; T197-F209 VanDerWaalsContact OG1-CE1 3.3Å; T197-F209 WeakPolarHBondContact OG1-CE1 3.35Å; T197-E210 PolarHBondContact O-N 3.14Å
198K92.4Very high83.9Confident54 Ų5476.5 Ų76.524%0.23543%0.427CS..BIsolated β-bridgetrans-64.6155177.5-64.4-169.8-173.51660111.9R182 E195 R200 R208R182-K198 WeakPolarHBondContact CD-O 3.4Å; R182-K198 PolarHBondContact NH1-O 2.9Å; E195-K198 WeakPolarHBondContact O-CB 3.37Å; E195-K198 PolarHBondContact O-N 3.39Å; E195-K198 IonicContact OE1-NZ 3.8Å; E195-K198 WeakPolarHBondContact OE2-CD 3.39Å; E195-K198 WeakPolarHBondContact OE2-CE 3.46Å; E195-K198 IonicContact OE2-NZ 3.26Å; E195-K198 PolarHBondContact OE2-NZ 3.38Å; K198-R200 PolarHBondContact O-N 3.16Å; K198-R208 CarbonylContact C-O 3.51Å; K198-R208 WeakPolarHBondContact CA-O 3.37Å
199C94.3Very high84.7Confident5 Ų577.6 Ų77.63%0.03441%0.411CS..  trans-57.9131.2177179.70000111.5H201 C202 G203 R208 E210 H214C199-H201 PolarHBondContact O-N 3.24Å; C199-H201 VanDerWaalsContact O-N 3.12Å; C199-C202 VanDerWaalsContact SG-SG 3.67Å; C199-G203 WeakPolarHBondContact O-CA 2.98Å; C199-G203 PolarHBondContact O-N 3.26Å; C199-R208 PolarHBondContact N-O 3.17Å; C199-E210 HydrophobicContact CB-CB 4.48Å; C199-H214 PolarHBondContact SG-NE2 3.2Å
200R93.1Very high85.5Confident128 Ų12876.2 Ų76.248%0.48340%0.399SS..THydrogen-bonded Turntrans-58.1-26179.3-66.1172.1-164.1-151.6-0.3114.1R182 K198 E210R182-R200 VanDerWaalsContact NE-CG 3.32Å; K198-R200 PolarHBondContact O-N 3.16Å; R200-E210 WeakPolarHBondContact CG-OE2 3.35Å; R200-E210 IonicContact NE-OE1 2.65Å; R200-E210 IonicContact NE-OE2 3.73Å; R200-E210 PolarHBondContact NE-OE2 2.98Å
201H93.3Very high86.9Confident120 Ų12069.8 Ų69.856%0.55637%0.367SS*.THydrogen-bonded Turntrans-111.8-33.2-170.9-57.8-69.6000114.2C199 T221C199-H201 PolarHBondContact O-N 3.24Å; C199-H201 VanDerWaalsContact O-N 3.12Å; H201-T221 HydrophobicContact CB-CG2 4.22Å; H201-T221 WeakPolarHBondContact CB-OG1 3.19Å
202C94.2Very high88.1Confident3 Ų364.3 Ų64.32%0.0234%0.344CS..THydrogen-bonded Turntrans-126.44.2179.174.30000113.4C199 S204 D205 T206 H214 R220C199-C202 VanDerWaalsContact SG-SG 3.67Å; C202-S204 PolarHBondContact O-N 3.27Å; C202-D205 PolarHBondContact O-N 3.04Å; C202-T206 HydrophobicContact CB-CG2 4.17Å; C202-T206 WeakPolarHBondContact O-CB 3.49Å; C202-T206 WeakPolarHBondContact O-CG2 3.33Å; C202-T206 PolarHBondContact O-N 3.41Å; C202-T206 PolarHBondContact O-OG1 3.48Å; C202-H214 PolarHBondContact SG-CE1 2.95Å; C202-H214 PolarHBondContact SG-NE2 3.25Å; C202-R220 HydrophobicContact CB-CG 4.12Å
203G92.2Very high89.4Confident0 Ų062.7 Ų62.70%034%0.343CS..Hα-helixtrans-64.8-37.7-175.200000113.1C199 D205 G207C199-G203 WeakPolarHBondContact O-CA 2.98Å; C199-G203 PolarHBondContact O-N 3.26Å; G203-D205 PolarHBondContact O-N 3.05Å; G203-G207 VanDerWaalsContact O-CA 3.23Å; G203-G207 WeakPolarHBondContact O-CA 3.49Å; G203-G207 PolarHBondContact O-N 2.98Å
204S91.2Very high90.7Very high96 Ų9658.2 Ų58.267%0.67131%0.305SS*.Hα-helixtrans-60-45.1178.2-530000111.9C202C202-S204 PolarHBondContact O-N 3.27Å
205D91.8Very high91.4Very high116 Ų11657.9 Ų57.962%0.6231%0.305SS*.Hα-helixtrans-86.8-35.1-176-50.90.3000113.1C202 G203 R220C202-D205 PolarHBondContact O-N 3.04Å; G203-D205 PolarHBondContact O-N 3.05Å; D205-R220 IonicContact OD2-CZ 3.1Å; D205-R220 IonicContact OD2-NH1 3.5Å; D205-R220 PolarHBondContact OD2-NH1 3.38Å; D205-R220 IonicContact OD2-NH2 3.27Å; D205-R220 PolarHBondContact OD2-NH2 3.27Å
206T91.3Very high91.8Very high64 Ų6455 Ų5539%0.39329%0.294SS..Hα-helixtrans-102.3-11.6-171.266.90000113.7C202 R208C202-T206 HydrophobicContact CB-CG2 4.17Å; C202-T206 WeakPolarHBondContact O-CB 3.49Å; C202-T206 WeakPolarHBondContact O-CG2 3.33Å; C202-T206 PolarHBondContact O-N 3.41Å; C202-T206 PolarHBondContact O-OG1 3.48Å; T206-R208 PolarHBondContact O-N 2.84Å; T206-R208 VanDerWaalsContact O-N 3.07Å; T206-R208 PolarHBondContact OG1-N 2.84Å
207G90.5Very high92.1Very high39 Ų3955.8 Ų55.840%0.40230%0.298SS..  trans65.92.1-17300000115.3G203G203-G207 VanDerWaalsContact O-CA 3.23Å; G203-G207 WeakPolarHBondContact O-CA 3.49Å; G203-G207 PolarHBondContact O-N 2.98Å
208R92Very high92.2Very high119 Ų11961 Ų6145%0.44932%0.322SS..  trans-74.9144.2-173.3-66.5-165.5-175.8-178.911113.2K198 C199 T206K198-R208 CarbonylContact C-O 3.51Å; K198-R208 WeakPolarHBondContact CA-O 3.37Å; C199-R208 PolarHBondContact N-O 3.17Å; T206-R208 PolarHBondContact O-N 2.84Å; T206-R208 VanDerWaalsContact O-N 3.07Å; T206-R208 PolarHBondContact OG1-N 2.84Å
209F92.2Very high92.3Very high99 Ų9958.6 Ų58.643%0.43431%0.312SS..BIsolated β-bridgetrans-74.5145.6173.9-58-59000113.6M183 T197 T211M183-F209 HydrophobicContact CG-CB 4.17Å; M183-F209 HydrophobicContact SD-CB 4.12Å; M183-F209 HydrophobicContact SD-CG 4.45Å; T197-F209 CarbonylContact O-C 3.53Å; T197-F209 WeakPolarHBondContact O-CA 3.25Å; T197-F209 VanDerWaalsContact OG1-CD1 3.24Å; T197-F209 WeakPolarHBondContact OG1-CD1 3.38Å; T197-F209 VanDerWaalsContact OG1-CE1 3.3Å; T197-F209 WeakPolarHBondContact OG1-CE1 3.35Å; F209-T211 VanDerWaalsContact C-N 3.31Å; F209-T211 HydrophobicContact CB-CG2 4.47Å; F209-T211 PolarHBondContact O-N 3.3Å
210E93.1Very high92.3Very high21 Ų2164.2 Ų64.210%0.09833%0.333CS..  trans-77.777.4176.1-151.6-164.8158.200111.5T181 R182 M183 T197 C199 R200T181-E210 WeakPolarHBondContact CB-O 3.33Å; T181-E210 PolarHBondContact OG1-O 3.08Å; R182-E210 HydrophobicContact CB-CB 3.9Å; R182-E210 VanDerWaalsContact CB-OE2 3.31Å; R182-E210 WeakPolarHBondContact CB-OE2 3.46Å; R182-E210 WeakPolarHBondContact CD-OE2 3.27Å; R182-E210 WeakPolarHBondContact CG-OE2 3.44Å; R182-E210 PolarHBondContact N-OE2 3.35Å; M183-E210 VanDerWaalsContact CB-O 3.25Å; M183-E210 WeakPolarHBondContact CB-O 3.01Å; M183-E210 WeakPolarHBondContact CG-O 3.34Å; M183-E210 PolarHBondContact N-O 2.97Å; T197-E210 PolarHBondContact O-N 3.14Å; C199-E210 HydrophobicContact CB-CB 4.48Å; R200-E210 WeakPolarHBondContact CG-OE2 3.35Å; R200-E210 IonicContact NE-OE1 2.65Å; R200-E210 IonicContact NE-OE2 3.73Å; R200-E210 PolarHBondContact NE-OE2 2.98Å
211T91.9Very high92.2Very high48 Ų4861.7 Ų61.729%0.29433%0.332SS..  trans-95.5159.8170.364.40000111.1M183 F209 A213 H214 A215M183-T211 HydrophobicContact CB-CG2 4.29Å; M183-T211 HydrophobicContact CG-CG2 3.8Å; F209-T211 VanDerWaalsContact C-N 3.31Å; F209-T211 HydrophobicContact CB-CG2 4.47Å; F209-T211 PolarHBondContact O-N 3.3Å; T211-A213 VanDerWaalsContact C-N 3.26Å; T211-A213 PolarHBondContact O-N 3.47Å; T211-H214 WeakPolarHBondContact O-CB 3.47Å; T211-H214 PolarHBondContact O-N 3.43Å; T211-H214 VanDerWaalsContact OG1-CB 3.28Å; T211-H214 WeakPolarHBondContact OG1-CB 3.38Å; T211-H214 PolarHBondContact OG1-N 3.35Å; T211-A215 PolarHBondContact O-N 3.04Å
212L90.9Very high92.2Very high21 Ų2157.6 Ų57.611%0.1132%0.315CS..Hα-helixtrans-58.2-41.1172.2179.461.8000111.8L174 V179 A215 V216L174-L212 HydrophobicContact CD2-CD1 3.69Å; L174-L212 HydrophobicContact CD2-CD2 4.15Å; L174-L212 HydrophobicContact CD2-CG 4.46Å; V179-L212 HydrophobicContact CB-CD1 4.02Å; V179-L212 HydrophobicContact CG1-CD1 4.25Å; V179-L212 HydrophobicContact CG2-CD1 3.86Å; V179-L212 HydrophobicContact CG2-CD2 4.5Å; L212-A215 PolarHBondContact O-N 2.84Å; L212-V216 HydrophobicContact CD1-CG2 3.6Å; L212-V216 HydrophobicContact CG-CG2 4.28Å; L212-V216 WeakPolarHBondContact O-CB 3.37Å; L212-V216 VanDerWaalsContact O-CG2 3.31Å; L212-V216 WeakPolarHBondContact O-CG2 3.49Å; L212-V216 PolarHBondContact O-N 3.14Å
213A91.9Very high92.1Very high52 Ų5262.5 Ų62.543%0.4334%0.337SS..Hα-helixtrans-61.6-44.4176.900000111.4T211 Q217T211-A213 VanDerWaalsContact C-N 3.26Å; T211-A213 PolarHBondContact O-N 3.47Å; A213-Q217 VanDerWaalsContact O-CB 3.27Å; A213-Q217 WeakPolarHBondContact O-CB 3.41Å; A213-Q217 PolarHBondContact O-N 3.41Å
214H94.1Very high92.1Very high4 Ų465.4 Ų65.42%0.01936%0.361CS..Iπ-helixtrans-59.9-53.2175173.670.2000111.5C199 C202 T211 V216 Q218 C219C199-H214 PolarHBondContact SG-NE2 3.2Å; C202-H214 PolarHBondContact SG-CE1 2.95Å; C202-H214 PolarHBondContact SG-NE2 3.25Å; T211-H214 WeakPolarHBondContact O-CB 3.47Å; T211-H214 PolarHBondContact O-N 3.43Å; T211-H214 VanDerWaalsContact OG1-CB 3.28Å; T211-H214 WeakPolarHBondContact OG1-CB 3.38Å; T211-H214 PolarHBondContact OG1-N 3.35Å; H214-V216 VanDerWaalsContact C-N 3.3Å; H214-V216 PolarHBondContact O-N 3Å; H214-Q218 CarbonylContact O-C 3.59Å; H214-Q218 PolarHBondContact O-N 3.46Å; H214-C219 WeakPolarHBondContact NE2-CB 3.31Å; H214-C219 PolarHBondContact O-N 3.5Å
215A92.2Very high92.1Very high27 Ų2766.3 Ų66.322%0.22336%0.358CS..Iπ-helixtrans-60-38.7-17800000112.7T211 L212 T222T211-A215 PolarHBondContact O-N 3.04Å; L212-A215 PolarHBondContact O-N 2.84Å; A215-T222 WeakPolarHBondContact O-CB 3.03Å; A215-T222 WeakPolarHBondContact O-CG2 3.45Å; A215-T222 PolarHBondContact O-OG1 3.24Å
216V90.7Very high92.1Very high40 Ų4062.6 Ų62.624%0.24234%0.335CS..Iπ-helixtrans-90.5-22.1-173.8178.20000113.7L212 H214 R226 R229L212-V216 HydrophobicContact CD1-CG2 3.6Å; L212-V216 HydrophobicContact CG-CG2 4.28Å; L212-V216 WeakPolarHBondContact O-CB 3.37Å; L212-V216 VanDerWaalsContact O-CG2 3.31Å; L212-V216 WeakPolarHBondContact O-CG2 3.49Å; L212-V216 PolarHBondContact O-N 3.14Å; H214-V216 VanDerWaalsContact C-N 3.3Å; H214-V216 PolarHBondContact O-N 3Å; V216-R226 WeakPolarHBondContact O-CD 3.2Å; V216-R226 WeakPolarHBondContact O-CG 3.25Å; V216-R229 VanDerWaalsContact CG1-NH1 3.34Å; V216-R229 PolarHBondContact O-NH2 3.41Å
217Q91.3Very high92Very high116 Ų11662.4 Ų62.454%0.54233%0.334SS..Iπ-helixtrans-123.8-27.2-172.2-58.2-61.7-12.400115A213 R226A213-Q217 VanDerWaalsContact O-CB 3.27Å; A213-Q217 WeakPolarHBondContact O-CB 3.41Å; A213-Q217 PolarHBondContact O-N 3.41Å; Q217-R226 PolarHBondContact O-NE 3.15Å
218Q92.5Very high91.9Very high109 Ų10965.4 Ų65.451%0.50934%0.34SS..Iπ-helixtrans-125.6-28-165.7-62.4-178.9-10.600114.9H214 R220H214-Q218 CarbonylContact O-C 3.59Å; H214-Q218 PolarHBondContact O-N 3.46Å; Q218-R220 PolarHBondContact O-N 2.99Å
219C94.9Very high91.8Very high3 Ų365 Ų652%0.0234%0.338CS..  trans-60.9130.8-174.4-1750000111H214 T221 T222 H223 R226H214-C219 WeakPolarHBondContact NE2-CB 3.31Å; H214-C219 PolarHBondContact O-N 3.5Å; C219-T221 VanDerWaalsContact C-N 3.28Å; C219-T221 PolarHBondContact O-N 2.88Å; C219-T222 PolarHBondContact O-N 2.98Å; C219-T222 PolarHBondContact O-OG1 3.13Å; C219-H223 PolarHBondContact O-N 3.12Å; C219-R226 PolarHBondContact O-NH1 3.44Å; C219-R226 PolarHBondContact O-NH2 2.85Å; C219-R226 VanDerWaalsContact O-NH2 3.11Å
220R92.7Very high91.5Very high124 Ų12465.7 Ų65.747%0.46834%0.342SS..SBendtrans-61.5-37178.363.4-174.3-178.9-163.3-2.6112.1C202 D205 Q218 T222 H223C202-R220 HydrophobicContact CB-CG 4.12Å; D205-R220 IonicContact OD2-CZ 3.1Å; D205-R220 IonicContact OD2-NH1 3.5Å; D205-R220 PolarHBondContact OD2-NH1 3.38Å; D205-R220 IonicContact OD2-NH2 3.27Å; D205-R220 PolarHBondContact OD2-NH2 3.27Å; Q218-R220 PolarHBondContact O-N 2.99Å; R220-T222 VanDerWaalsContact C-N 3.3Å; R220-T222 PolarHBondContact O-N 2.9Å; R220-H223 WeakPolarHBondContact O-CB 3.28Å; R220-H223 PolarHBondContact O-N 3Å; R220-H223 VanDerWaalsContact O-N 3.08Å
221T92.3Very high91.2Very high75 Ų7568.7 Ų68.746%0.4636%0.359SS..THydrogen-bonded Turntrans-63.9-33.7179.8-47.40000112.6H201 C219H201-T221 HydrophobicContact CB-CG2 4.22Å; H201-T221 WeakPolarHBondContact CB-OG1 3.19Å; C219-T221 VanDerWaalsContact C-N 3.28Å; C219-T221 PolarHBondContact O-N 2.88Å
222T92.4Very high90.9Very high34 Ų3469.5 Ų69.521%0.20936%0.364CS..THydrogen-bonded Turntrans-93.15.6177.761.90000113A215 C219 R220 A224 L225 R226A215-T222 WeakPolarHBondContact O-CB 3.03Å; A215-T222 WeakPolarHBondContact O-CG2 3.45Å; A215-T222 PolarHBondContact O-OG1 3.24Å; C219-T222 PolarHBondContact O-N 2.98Å; C219-T222 PolarHBondContact O-OG1 3.13Å; R220-T222 VanDerWaalsContact C-N 3.3Å; R220-T222 PolarHBondContact O-N 2.9Å; T222-A224 PolarHBondContact O-N 2.87Å; T222-L225 PolarHBondContact O-N 3.26Å; T222-R226 WeakPolarHBondContact O-CG 3.16Å; T222-R226 PolarHBondContact O-N 2.88Å; T222-R226 PolarHBondContact OG1-NH1 3.33Å
223H92Very high90.4Very high105 Ų10572.4 Ų72.449%0.48638%0.379SS..Hα-helixtrans-58.5-50.2-178179.5-99.8000112.1C219 R220 L225 R226 V227C219-H223 PolarHBondContact O-N 3.12Å; R220-H223 WeakPolarHBondContact O-CB 3.28Å; R220-H223 PolarHBondContact O-N 3Å; R220-H223 VanDerWaalsContact O-N 3.08Å; H223-L225 VanDerWaalsContact C-N 3.28Å; H223-L225 PolarHBondContact O-N 3.48Å; H223-R226 WeakPolarHBondContact O-CB 3.5Å; H223-R226 PolarHBondContact O-N 3.33Å; H223-V227 WeakPolarHBondContact O-CG2 3.38Å; H223-V227 PolarHBondContact O-N 3.45Å
224A92Very high89.9Confident61 Ų6171.8 Ų71.850%0.50437%0.37SS..Hα-helixtrans-56.9-42.1177.800000112T222 R226 V227 I228T222-A224 PolarHBondContact O-N 2.87Å; A224-R226 VanDerWaalsContact C-N 3.35Å; A224-R226 PolarHBondContact O-N 2.87Å; A224-V227 PolarHBondContact O-N 3.36Å; A224-I228 WeakPolarHBondContact O-CG1 3.49Å; A224-I228 PolarHBondContact O-N 2.89Å
225L92Very high89.1Confident115 Ų11574 Ų7460%0.60239%0.386SS*.Hα-helixtrans-65.3-35.7176.4-62.8176.2000112.6T222 H223 R229T222-L225 PolarHBondContact O-N 3.26Å; H223-L225 VanDerWaalsContact C-N 3.28Å; H223-L225 PolarHBondContact O-N 3.48Å; L225-R229 WeakPolarHBondContact O-CB 3.5Å; L225-R229 PolarHBondContact O-N 3.19Å
226R91.4Very high88.2Confident39 Ų3980.9 Ų80.915%0.14741%0.406CS..Hα-helixtrans-64.3-43.2173.1-69.7-168.1-61.9-84.411.5111.3V216 Q217 C219 T222 H223 A224 R229 H230V216-R226 WeakPolarHBondContact O-CD 3.2Å; V216-R226 WeakPolarHBondContact O-CG 3.25Å; Q217-R226 PolarHBondContact O-NE 3.15Å; C219-R226 PolarHBondContact O-NH1 3.44Å; C219-R226 PolarHBondContact O-NH2 2.85Å; C219-R226 VanDerWaalsContact O-NH2 3.11Å; T222-R226 WeakPolarHBondContact O-CG 3.16Å; T222-R226 PolarHBondContact O-N 2.88Å; T222-R226 PolarHBondContact OG1-NH1 3.33Å; H223-R226 WeakPolarHBondContact O-CB 3.5Å; H223-R226 PolarHBondContact O-N 3.33Å; A224-R226 VanDerWaalsContact C-N 3.35Å; A224-R226 PolarHBondContact O-N 2.87Å; R226-R229 PolarHBondContact O-N 3.38Å; R226-H230 WeakPolarHBondContact O-CB 3.13Å; R226-H230 PolarHBondContact O-N 3.47Å
227V89.5Confident87.2Confident60 Ų6083.6 Ų83.636%0.36442%0.415SS..Hα-helixtrans-63-46.5177.3174.80000110.5H223 A224 R229 H230 N231H223-V227 WeakPolarHBondContact O-CG2 3.38Å; H223-V227 PolarHBondContact O-N 3.45Å; A224-V227 PolarHBondContact O-N 3.36Å; V227-R229 PolarHBondContact O-N 2.95Å; V227-H230 WeakPolarHBondContact O-CB 3.47Å; V227-H230 PolarHBondContact O-N 3.04Å; V227-N231 WeakPolarHBondContact O-CB 3.31Å; V227-N231 VanDerWaalsContact O-CG 3.22Å; V227-N231 PolarHBondContact O-N 3.22Å; V227-N231 PolarHBondContact O-OD1 3.45Å
228I89.1Confident85.8Confident102 Ų10283.7 Ų83.752%0.52341%0.413SS..Hα-helixtrans-57.8-51.3175.5-68.9165.3000110.3A224 H230 N231 T232A224-I228 WeakPolarHBondContact O-CG1 3.49Å; A224-I228 PolarHBondContact O-N 2.89Å; I228-H230 VanDerWaalsContact C-N 3.32Å; I228-H230 PolarHBondContact O-N 3.11Å; I228-N231 PolarHBondContact O-N 2.98Å; I228-N231 VanDerWaalsContact O-N 3.17Å; I228-T232 PolarHBondContact O-N 3.03Å; I228-T232 PolarHBondContact O-OG1 3.11Å
229R88Confident84.2Confident111 Ų11186.1 Ų86.142%0.41943%0.425SS..Hα-helixtrans-56.7-46177.7179.2-17664.3178-4.6111.8V216 L225 R226 V227 T232 L233V216-R229 VanDerWaalsContact CG1-NH1 3.34Å; V216-R229 PolarHBondContact O-NH2 3.41Å; L225-R229 WeakPolarHBondContact O-CB 3.5Å; L225-R229 PolarHBondContact O-N 3.19Å; R226-R229 PolarHBondContact O-N 3.38Å; V227-R229 PolarHBondContact O-N 2.95Å; R229-T232 PolarHBondContact O-N 2.97Å; R229-L233 HydrophobicContact CG-CD1 4.45Å; R229-L233 WeakPolarHBondContact O-CG 3.43Å; R229-L233 PolarHBondContact O-N 2.73Å; R229-L233 VanDerWaalsContact O-N 3.08Å
230H86.7Confident82.5Confident112 Ų11288.5 Ų88.552%0.51945%0.445SS..Hα-helixtrans-58.9-50.3177171.2-89.9000110.6R226 V227 I228 T232 L233 V234R226-H230 WeakPolarHBondContact O-CB 3.13Å; R226-H230 PolarHBondContact O-N 3.47Å; V227-H230 WeakPolarHBondContact O-CB 3.47Å; V227-H230 PolarHBondContact O-N 3.04Å; I228-H230 VanDerWaalsContact C-N 3.32Å; I228-H230 PolarHBondContact O-N 3.11Å; H230-T232 PolarHBondContact O-N 3.3Å; H230-L233 PolarHBondContact O-N 2.89Å; H230-L233 VanDerWaalsContact O-N 3.14Å; H230-V234 VanDerWaalsContact CE1-CG2 3.5Å; H230-V234 WeakPolarHBondContact CE1-CG2 3.04Å; H230-V234 WeakPolarHBondContact O-CB 3.16Å; H230-V234 WeakPolarHBondContact O-CG2 3.47Å; H230-V234 PolarHBondContact O-N 2.83Å
231N87Confident81.2Confident85 Ų8584.6 Ų84.646%0.45543%0.433SS..Hα-helixtrans-64.7-37.5-178.4-68.3-6.7000112.3V227 I228 L233 V234 S235V227-N231 WeakPolarHBondContact O-CB 3.31Å; V227-N231 VanDerWaalsContact O-CG 3.22Å; V227-N231 PolarHBondContact O-N 3.22Å; V227-N231 PolarHBondContact O-OD1 3.45Å; I228-N231 PolarHBondContact O-N 2.98Å; I228-N231 VanDerWaalsContact O-N 3.17Å; N231-L233 VanDerWaalsContact C-N 3.34Å; N231-V234 PolarHBondContact O-N 3.21Å; N231-S235 WeakPolarHBondContact O-CB 3.38Å; N231-S235 PolarHBondContact O-N 2.92Å; N231-S235 PolarHBondContact O-OG 2.64Å
232T84.6Confident80Confident64 Ų6485.3 Ų85.339%0.39343%0.434SS..Hα-helixtrans-64-37.4173.4-55.50000112.4I228 R229 H230 S235 R236I228-T232 PolarHBondContact O-N 3.03Å; I228-T232 PolarHBondContact O-OG1 3.11Å; R229-T232 PolarHBondContact O-N 2.97Å; H230-T232 PolarHBondContact O-N 3.3Å; T232-S235 PolarHBondContact O-OG 3.1Å; T232-R236 WeakPolarHBondContact O-CG 3.43Å; T232-R236 PolarHBondContact O-N 3.4Å
233L81.7Confident79Confident82 Ų8287.9 Ų87.943%0.42945%0.445SS..Hα-helixtrans-70.6-46174.4-70.2174.3000110.5R229 H230 N231 S235 R236 F237R229-L233 HydrophobicContact CG-CD1 4.45Å; R229-L233 WeakPolarHBondContact O-CG 3.43Å; R229-L233 PolarHBondContact O-N 2.73Å; R229-L233 VanDerWaalsContact O-N 3.08Å; H230-L233 PolarHBondContact O-N 2.89Å; H230-L233 VanDerWaalsContact O-N 3.14Å; N231-L233 VanDerWaalsContact C-N 3.34Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 3.32Å; L233-R236 PolarHBondContact O-N 2.74Å; L233-F237 HydrophobicContact CB-CD2 4.35Å; L233-F237 HydrophobicContact CB-CE2 4.19Å; L233-F237 WeakPolarHBondContact O-CD2 3.38Å; L233-F237 WeakPolarHBondContact O-CG 3.31Å; L233-F237 PolarHBondContact O-N 3.34Å
234V80.2Confident78.2Confident39 Ų3987.4 Ų87.424%0.23645%0.446CS..Hα-helixtrans-59.7-39.5177.8168.80000111.4H230 N231 F237 K238H230-V234 VanDerWaalsContact CE1-CG2 3.5Å; H230-V234 WeakPolarHBondContact CE1-CG2 3.04Å; H230-V234 WeakPolarHBondContact O-CB 3.16Å; H230-V234 WeakPolarHBondContact O-CG2 3.47Å; H230-V234 PolarHBondContact O-N 2.83Å; N231-V234 PolarHBondContact O-N 3.21Å; V234-F237 CarbonylContact O-C 3.59Å; V234-F237 PolarHBondContact O-N 2.83Å; V234-K238 HydrophobicContact CG1-CD 3.72Å; V234-K238 HydrophobicContact CG1-CG 3.93Å; V234-K238 VanDerWaalsContact O-CB 3.25Å; V234-K238 WeakPolarHBondContact O-CB 3.4Å; V234-K238 VanDerWaalsContact O-CG 3.25Å; V234-K238 WeakPolarHBondContact O-CG 3.24Å; V234-K238 PolarHBondContact O-N 2.92Å
235S77.3Confident77.5Confident51 Ų5194 Ų9436%0.35746%0.458SS..Hα-helixtrans-63.6-44.6176.867.60000111.6N231 T232 L233 F237 K238 E239N231-S235 WeakPolarHBondContact O-CB 3.38Å; N231-S235 PolarHBondContact O-N 2.92Å; N231-S235 PolarHBondContact O-OG 2.64Å; T232-S235 PolarHBondContact O-OG 3.1Å; L233-S235 VanDerWaalsContact C-N 3.3Å; L233-S235 PolarHBondContact O-N 3.32Å; S235-F237 VanDerWaalsContact C-N 3.26Å; S235-F237 PolarHBondContact O-N 2.92Å; S235-K238 PolarHBondContact O-N 2.94Å; S235-E239 PolarHBondContact O-N 3.04Å
236R75Confident76.9Confident172 Ų17299.1 Ų99.165%0.64947%0.469SS*.Hα-helixtrans-61.8-31.5175.6-70.1178.6-179.4-163.6-1113.4T232 L233T232-R236 WeakPolarHBondContact O-CG 3.43Å; T232-R236 PolarHBondContact O-N 3.4Å; L233-R236 PolarHBondContact O-N 2.74Å
237F68.2Low76.6Confident97 Ų97100.1 Ų100.143%0.42549%0.491SS..Hα-helixtrans-90.6-22.5177.9-67.2-56.2000114.1L233 V234 S235 E239 M255L233-F237 HydrophobicContact CB-CD2 4.35Å; L233-F237 HydrophobicContact CB-CE2 4.19Å; L233-F237 WeakPolarHBondContact O-CD2 3.38Å; L233-F237 WeakPolarHBondContact O-CG 3.31Å; L233-F237 PolarHBondContact O-N 3.34Å; V234-F237 CarbonylContact O-C 3.59Å; V234-F237 PolarHBondContact O-N 2.83Å; S235-F237 VanDerWaalsContact C-N 3.26Å; S235-F237 PolarHBondContact O-N 2.92Å; F237-E239 VanDerWaalsContact C-N 3.29Å; F237-M255 HydrophobicContact CB-CE 3.64Å; F237-M255 HydrophobicContact CD1-CE 3.13Å; F237-M255 HydrophobicContact CD2-CE 3.9Å; F237-M255 HydrophobicContact CE1-CE 3.63Å; F237-M255 HydrophobicContact CE2-CE 4.34Å; F237-M255 HydrophobicContact CG-CE 3.28Å; F237-M255 HydrophobicContact CZ-CE 4.21Å
238K63.2Low76.3Confident117 Ų117106.8 Ų106.851%0.50952%0.518SS..Hα-helixtrans-67.7-33.7174.5-88.4177.9175.1-177.60111.4V234 S235 A256V234-K238 HydrophobicContact CG1-CD 3.72Å; V234-K238 HydrophobicContact CG1-CG 3.93Å; V234-K238 VanDerWaalsContact O-CB 3.25Å; V234-K238 WeakPolarHBondContact O-CB 3.4Å; V234-K238 VanDerWaalsContact O-CG 3.25Å; V234-K238 WeakPolarHBondContact O-CG 3.24Å; V234-K238 PolarHBondContact O-N 2.92Å; S235-K238 PolarHBondContact O-N 2.94Å; K238-A256 HydrophobicContact CB-CB 4.47Å; K238-A256 HydrophobicContact CD-CB 4.33Å; K238-A256 HydrophobicContact CG-CB 3.37Å
239E58.8Low75.9Confident161 Ų161110.9 Ų110.975%0.75253%0.527SS*.Hα-helixtrans-82.6-28.5178.9-68168.1-163.100112.4S235 F237S235-E239 PolarHBondContact O-N 3.04Å; F237-E239 VanDerWaalsContact C-N 3.29Å
240A59.2Low75.5Confident52 Ų52109.3 Ų109.343%0.4353%0.527SS..  trans-94.1105.6-176.200000111.8
241D65.4Low75.1Confident42 Ų42106.3 Ų106.323%0.22552%0.518CS..  trans-82.1124.2168.4-61.9-39.2000110.2I243 I252 H254 K275 Y276D241-I243 HydrophobicContact CB-CG1 4.37Å; D241-I243 PolarHBondContact O-N 3.26Å; D241-I252 HydrophobicContact CB-CG2 4.33Å; D241-H254 IonicContact OD1-CD2 3.65Å; D241-H254 PolarHBondContact OD1-CD2 3.21Å; D241-H254 IonicContact OD1-CG 3.02Å; D241-H254 IonicContact OD1-NE2 3Å; D241-K275 IonicContact OD1-NZ 3.82Å; D241-K275 WeakPolarHBondContact OD2-CE 3.43Å; D241-K275 IonicContact OD2-NZ 3.44Å; D241-K275 PolarHBondContact OD2-NZ 2.93Å; D241-Y276 PolarHBondContact OD1-OH 3.48Å; D241-Y276 PolarHBondContact OD2-OH 3.47Å
242L65.5Low74.5Confident91 Ų91104.8 Ų104.848%0.47651%0.509SS..EExtended strand (participates in β ladder)trans-83100.7171.3-75.8173.2000108.6I253 M255L242-I253 HydrophobicContact CB-CB 3.98Å; L242-I253 PolarHBondContact N-O 2.89Å; L242-I253 PolarHBondContact O-N 3.04Å; L242-M255 HydrophobicContact CD1-SD 4.45Å
243I71.7Confident73.8Confident88 Ų88105.4 Ų105.445%0.45151%0.51SS..EExtended strand (participates in β ladder)trans-94.2113.4175.2-54.7176.8000108.7D241 L250 I252 L279D241-I243 HydrophobicContact CB-CG1 4.37Å; D241-I243 PolarHBondContact O-N 3.26Å; I243-L250 HydrophobicContact CG2-CD2 3.7Å; I243-I252 HydrophobicContact CG1-CG1 4.29Å; I243-I252 HydrophobicContact CG1-CG2 4.31Å; I243-I252 HydrophobicContact CG2-CG1 4.4Å; I243-L279 HydrophobicContact CD1-CD1 4.41Å
244L76.2Confident73Confident95 Ų95103.1 Ų103.150%0.49750%0.497SS..EExtended strand (participates in β ladder)trans-104.7118.8175.2-59.2174.2000109.2S251 I253L244-S251 PolarHBondContact N-O 3.32Å; L244-S251 PolarHBondContact O-N 3.31Å; L244-I253 HydrophobicContact CD1-CD1 3.65Å; L244-I253 HydrophobicContact CD1-CG1 4.48Å; L244-I253 HydrophobicContact CG-CD1 4.49Å
245R77.8Confident72.1Confident200 Ų200105.8 Ų105.876%0.75551%0.508SS*.EExtended strand (participates in β ladder)trans-102.7125.5175.1-173.1177.1174.4173.2-0.6110.4G247 L250R245-G247 PolarHBondContact NE-O 2.95Å; R245-L250 HydrophobicContact CB-CD2 3.86Å; R245-L250 HydrophobicContact CG-CD2 4Å
246R78.5Confident71.4Confident222 Ų222104.2 Ų104.284%0.83850%0.498SS*.EExtended strand (participates in β ladder)trans-127.6100.7171.2-168.1178.4-177.1-179.10.2109.3Q248 R249R246-Q248 PolarHBondContact O-N 3.38Å; R246-R249 PolarHBondContact N-O 3.39Å; R246-R249 PolarHBondContact O-N 2.93Å
247G84.4Confident70.6Confident59 Ų5998 Ų9861%0.60848%0.479SS*.THydrogen-bonded Turntrans61.8-122.8-173.100000111.3R245R245-G247 PolarHBondContact NE-O 2.95Å
248Q83.4Confident70.3Confident200 Ų20095.7 Ų95.794%0.93547%0.473SS*.THydrogen-bonded Turntrans-82.9-9.2174-72.4179-21.600113.8R246R246-Q248 PolarHBondContact O-N 3.38Å
249R80.9Confident70.3Confident189 Ų18999.2 Ų99.271%0.71348%0.484SS*.EExtended strand (participates in β ladder)trans-90.9122-178.1-169.2172.8179.4158.61.3111.2R246R246-R249 PolarHBondContact N-O 3.39Å; R246-R249 PolarHBondContact O-N 2.93Å
250L79.6Confident71.2Confident78 Ų7897.1 Ų97.141%0.40848%0.478SS..EExtended strand (participates in β ladder)trans-98.2126.3167.8-75.3159.5000109.5I243 R245I243-L250 HydrophobicContact CG2-CD2 3.7Å; R245-L250 HydrophobicContact CB-CD2 3.86Å; R245-L250 HydrophobicContact CG-CD2 4Å
251S79.3Confident72.4Confident49 Ų4996.1 Ų96.134%0.34347%0.468SS..EExtended strand (participates in β ladder)trans-115.7111.9174.8-68.30000108.6L244L244-S251 PolarHBondContact N-O 3.32Å; L244-S251 PolarHBondContact O-N 3.31Å
252I73.6Confident73.3Confident52 Ų5299.6 Ų99.627%0.26749%0.492SS..EExtended strand (participates in β ladder)trans-102.2112.9-178.6-52.7176.9000108.7D241 I243 Y276 L279D241-I252 HydrophobicContact CB-CG2 4.33Å; I243-I252 HydrophobicContact CG1-CG1 4.29Å; I243-I252 HydrophobicContact CG1-CG2 4.31Å; I243-I252 HydrophobicContact CG2-CG1 4.4Å; I252-Y276 HydrophobicContact CD1-CD1 3.4Å; I252-Y276 HydrophobicContact CD1-CD2 3.93Å; I252-Y276 HydrophobicContact CD1-CE1 4Å; I252-Y276 HydrophobicContact CD1-CE2 4.49Å; I252-Y276 HydrophobicContact CD1-CG 3.37Å; I252-Y276 HydrophobicContact CG2-CD1 4.29Å; I252-Y276 HydrophobicContact CG2-CD2 4.14Å; I252-Y276 HydrophobicContact CG2-CE1 3.83Å; I252-Y276 HydrophobicContact CG2-CE2 3.7Å; I252-Y276 HydrophobicContact CG2-CG 4.43Å; I252-L279 HydrophobicContact CD1-CD1 3.68Å
253I70.1Confident74.3Confident78 Ų78102.9 Ų102.940%0.451%0.505SS..EExtended strand (participates in β ladder)trans-97.1101.5176.5-56.1172.5000107.8L242 L244 M255L242-I253 HydrophobicContact CB-CB 3.98Å; L242-I253 PolarHBondContact N-O 2.89Å; L242-I253 PolarHBondContact O-N 3.04Å; L244-I253 HydrophobicContact CD1-CD1 3.65Å; L244-I253 HydrophobicContact CD1-CG1 4.48Å; L244-I253 HydrophobicContact CG-CD1 4.49Å; I253-M255 HydrophobicContact CG2-CG 4.04Å
254H65.5Low74.7Confident33 Ų33105.6 Ų105.615%0.15351%0.51CS..  trans-98.2100.1173.8-171.4-65.8000110.2D241 A256 K272 Y276D241-H254 IonicContact OD1-CD2 3.65Å; D241-H254 PolarHBondContact OD1-CD2 3.21Å; D241-H254 IonicContact OD1-CG 3.02Å; D241-H254 IonicContact OD1-NE2 3Å; H254-A256 VanDerWaalsContact C-N 3.27Å; H254-A256 PolarHBondContact ND1-O 3.24Å; H254-A256 PolarHBondContact O-N 3.26Å; H254-A256 VanDerWaalsContact O-N 3.16Å; H254-K272 HydrophobicContact CB-CD 4.12Å; H254-K272 VanDerWaalsContact CG-CE 3.5Å; H254-K272 WeakPolarHBondContact ND1-CE 3.23Å; H254-K272 PolarHBondContact ND1-NZ 3.04Å; H254-Y276 PolarHBondContact CD2-OH 2.89Å; H254-Y276 VanDerWaalsContact CD2-OH 3.32Å
255M60.4Low74.8Confident95 Ų95103.9 Ų103.947%0.46850%0.499SS..  trans-71.6-9.5-166.8-63.1-158.2-47.600116F237 L242 I253F237-M255 HydrophobicContact CB-CE 3.64Å; F237-M255 HydrophobicContact CD1-CE 3.13Å; F237-M255 HydrophobicContact CD2-CE 3.9Å; F237-M255 HydrophobicContact CE1-CE 3.63Å; F237-M255 HydrophobicContact CE2-CE 4.34Å; F237-M255 HydrophobicContact CG-CE 3.28Å; F237-M255 HydrophobicContact CZ-CE 4.21Å; L242-M255 HydrophobicContact CD1-SD 4.45Å; I253-M255 HydrophobicContact CG2-CG 4.04Å
256A61.9Low75.2Confident18 Ų1897 Ų9715%0.14948%0.484CS..  trans-102.993.7175.700000111.4K238 H254 K272K238-A256 HydrophobicContact CB-CB 4.47Å; K238-A256 HydrophobicContact CD-CB 4.33Å; K238-A256 HydrophobicContact CG-CB 3.37Å; H254-A256 VanDerWaalsContact C-N 3.27Å; H254-A256 PolarHBondContact ND1-O 3.24Å; H254-A256 PolarHBondContact O-N 3.26Å; H254-A256 VanDerWaalsContact O-N 3.16Å; A256-K272 PolarHBondContact O-NZ 3.05Å
257V58.6Low75.4Confident41 Ų4189.5 Ų89.525%0.24847%0.47CS..  trans-113115.9158.2-161.60000106.6W259 F265V257-W259 VanDerWaalsContact O-CD1 3.22Å; V257-W259 PolarHBondContact O-N 3.48Å; V257-F265 HydrophobicContact CB-CD2 4.35Å; V257-F265 HydrophobicContact CB-CE2 4.41Å; V257-F265 HydrophobicContact CG1-CD2 3.31Å; V257-F265 HydrophobicContact CG1-CE2 3.65Å; V257-F265 HydrophobicContact CG1-CG 4.25Å
258P62.1Low75.3Confident49 Ų4987.6 Ų87.632%0.31845%0.447SS..  trans-59121.6166.3-16.329.3000108.2D260P258-D260 VanDerWaalsContact C-N 3.31Å
259W64.2Low75.2Confident192 Ų19284.4 Ų84.473%0.72743%0.427SS*.  trans-956.2174.4-71.896.9000111.9V257 S261 F265V257-W259 VanDerWaalsContact O-CD1 3.22Å; V257-W259 PolarHBondContact O-N 3.48Å; W259-S261 PolarHBondContact O-N 3.08Å; W259-F265 HydrophobicContact CD2-CD2 4.04Å; W259-F265 HydrophobicContact CD2-CE2 4.3Å; W259-F265 AromaticContact CE3-CD2 3.68Å; W259-F265 HydrophobicContact CE3-CD2 3.68Å; W259-F265 AromaticContact CE3-CE2 3.97Å; W259-F265 HydrophobicContact CE3-CE2 3.97Å; W259-F265 HydrophobicContact CE3-CG 4.41Å; W259-F265 AromaticContact CH2-CD2 3.86Å; W259-F265 HydrophobicContact CH2-CD2 3.86Å; W259-F265 AromaticContact CH2-CE2 3.23Å; W259-F265 HydrophobicContact CH2-CE2 3.23Å; W259-F265 AromaticContact CH2-CZ 3.77Å; W259-F265 HydrophobicContact CH2-CZ 3.77Å; W259-F265 HydrophobicContact CZ2-CD2 4.18Å; W259-F265 AromaticContact CZ2-CE2 3.59Å; W259-F265 HydrophobicContact CZ2-CE2 3.59Å; W259-F265 HydrophobicContact CZ2-CZ 4.44Å; W259-F265 AromaticContact CZ3-CD2 3.58Å; W259-F265 HydrophobicContact CZ3-CD2 3.58Å; W259-F265 AromaticContact CZ3-CE2 3.43Å; W259-F265 HydrophobicContact CZ3-CE2 3.43Å; W259-F265 VanDerWaalsContact CZ3-CE2 3.43Å; W259-F265 HydrophobicContact CZ3-CG 4.29Å; W259-F265 HydrophobicContact CZ3-CZ 4Å
260D77.4Confident75.4Confident116 Ų11678.2 Ų78.262%0.6242%0.416SS*.SBendtrans-63.1-30-169.5-23.5-29.6000112.6P258 R264P258-D260 VanDerWaalsContact C-N 3.31Å; D260-R264 IonicContact OD2-NH1 2.95Å; D260-R264 PolarHBondContact OD2-NH1 3.26Å
261S82.9Confident75.6Confident32 Ų3281.3 Ų81.322%0.22442%0.423CS..  trans-148.8150.217273.30000111.9W259 E263 R264 F265W259-S261 PolarHBondContact O-N 3.08Å; S261-E263 PolarHBondContact O-N 3.33Å; S261-R264 PolarHBondContact O-N 3.39Å; S261-R264 WeakPolarHBondContact OG-CB 3.48Å; S261-R264 WeakPolarHBondContact OG-CG 3.2Å; S261-R264 PolarHBondContact OG-N 3.33Å; S261-R264 VanDerWaalsContact OG-N 3.16Å; S261-F265 PolarHBondContact O-N 3.3Å
262P85Confident75.6Confident114 Ų11480.1 Ų80.174%0.7441%0.412SS*.Hα-helixtrans-54.8-36.5175.1-25.634.3000113F265 A266P262-F265 WeakPolarHBondContact O-CB 3.3Å; P262-F265 PolarHBondContact O-N 3.25Å; P262-A266 WeakPolarHBondContact O-CB 3.27Å; P262-A266 PolarHBondContact O-N 3.39Å
263E86.3Confident76.1Confident160 Ų16085.7 Ų85.775%0.74843%0.43SS*.Hα-helixtrans-66.4-47.9178.6-64.9169.8-176.400112.2S261 F265 A266 A267S261-E263 PolarHBondContact O-N 3.33Å; E263-F265 VanDerWaalsContact C-N 3.27Å; E263-F265 PolarHBondContact O-N 3.25Å; E263-A266 PolarHBondContact O-N 2.98Å; E263-A267 WeakPolarHBondContact O-CB 3.31Å; E263-A267 PolarHBondContact O-N 2.87Å
264R79.6Confident76.8Confident146 Ų14685.5 Ų85.555%0.55144%0.436SS*.Hα-helixtrans-63-37.2176-78-177.9176.3-1793.1111.4D260 S261 S268D260-R264 IonicContact OD2-NH1 2.95Å; D260-R264 PolarHBondContact OD2-NH1 3.26Å; S261-R264 PolarHBondContact O-N 3.39Å; S261-R264 WeakPolarHBondContact OG-CB 3.48Å; S261-R264 WeakPolarHBondContact OG-CG 3.2Å; S261-R264 PolarHBondContact OG-N 3.33Å; S261-R264 VanDerWaalsContact OG-N 3.16Å; R264-S268 WeakPolarHBondContact O-CB 3.35Å; R264-S268 PolarHBondContact O-N 3.41Å
265F80.1Confident77.6Confident59 Ų5987.6 Ų87.626%0.25944%0.444SS..Hα-helixtrans-61.9-49.3174178.5-92.7000111.1V257 W259 S261 P262 E263 S268 R269V257-F265 HydrophobicContact CB-CD2 4.35Å; V257-F265 HydrophobicContact CB-CE2 4.41Å; V257-F265 HydrophobicContact CG1-CD2 3.31Å; V257-F265 HydrophobicContact CG1-CE2 3.65Å; V257-F265 HydrophobicContact CG1-CG 4.25Å; W259-F265 HydrophobicContact CD2-CD2 4.04Å; W259-F265 HydrophobicContact CD2-CE2 4.3Å; W259-F265 AromaticContact CE3-CD2 3.68Å; W259-F265 HydrophobicContact CE3-CD2 3.68Å; W259-F265 AromaticContact CE3-CE2 3.97Å; W259-F265 HydrophobicContact CE3-CE2 3.97Å; W259-F265 HydrophobicContact CE3-CG 4.41Å; W259-F265 AromaticContact CH2-CD2 3.86Å; W259-F265 HydrophobicContact CH2-CD2 3.86Å; W259-F265 AromaticContact CH2-CE2 3.23Å; W259-F265 HydrophobicContact CH2-CE2 3.23Å; W259-F265 AromaticContact CH2-CZ 3.77Å; W259-F265 HydrophobicContact CH2-CZ 3.77Å; W259-F265 HydrophobicContact CZ2-CD2 4.18Å; W259-F265 AromaticContact CZ2-CE2 3.59Å; W259-F265 HydrophobicContact CZ2-CE2 3.59Å; W259-F265 HydrophobicContact CZ2-CZ 4.44Å; W259-F265 AromaticContact CZ3-CD2 3.58Å; W259-F265 HydrophobicContact CZ3-CD2 3.58Å; W259-F265 AromaticContact CZ3-CE2 3.43Å; W259-F265 HydrophobicContact CZ3-CE2 3.43Å; W259-F265 VanDerWaalsContact CZ3-CE2 3.43Å; W259-F265 HydrophobicContact CZ3-CG 4.29Å; W259-F265 HydrophobicContact CZ3-CZ 4Å; S261-F265 PolarHBondContact O-N 3.3Å; P262-F265 WeakPolarHBondContact O-CB 3.3Å; P262-F265 PolarHBondContact O-N 3.25Å; E263-F265 VanDerWaalsContact C-N 3.27Å; E263-F265 PolarHBondContact O-N 3.25Å; F265-S268 PolarHBondContact O-N 2.77Å; F265-R269 VanDerWaalsContact O-CB 3.32Å; F265-R269 WeakPolarHBondContact O-CB 3.34Å; F265-R269 PolarHBondContact O-N 3.07Å
266A84.3Confident78.5Confident55 Ų5584.5 Ų84.546%0.45543%0.427SS..Hα-helixtrans-61.7-46.1178.900000112.1P262 E263 R269 A270P262-A266 WeakPolarHBondContact O-CB 3.27Å; P262-A266 PolarHBondContact O-N 3.39Å; E263-A266 PolarHBondContact O-N 2.98Å; A266-R269 PolarHBondContact O-N 3.2Å; A266-A270 WeakPolarHBondContact O-CB 3.15Å; A266-A270 PolarHBondContact O-N 2.86Å
267A84.7Confident79.5Confident64 Ų6486 Ų8653%0.52944%0.44SS..Hα-helixtrans-61.3-45.4176.500000112E263 R269 A270 Y271E263-A267 WeakPolarHBondContact O-CB 3.31Å; E263-A267 PolarHBondContact O-N 2.87Å; A267-R269 VanDerWaalsContact C-N 3.33Å; A267-R269 PolarHBondContact O-N 2.6Å; A267-A270 PolarHBondContact O-N 2.95Å; A267-Y271 WeakPolarHBondContact O-CB 2.98Å; A267-Y271 PolarHBondContact O-N 3.14Å
268S80.6Confident80.5Confident20 Ų2090.2 Ų90.214%0.1447%0.465CS..Hα-helixtrans-63.6-38.9176.1-170.90000111.9R264 F265 K272R264-S268 WeakPolarHBondContact O-CB 3.35Å; R264-S268 PolarHBondContact O-N 3.41Å; F265-S268 PolarHBondContact O-N 2.77Å; S268-K272 WeakPolarHBondContact O-CB 3.07Å; S268-K272 WeakPolarHBondContact O-CD 3.34Å; S268-K272 WeakPolarHBondContact O-CG 3.49Å; S268-K272 PolarHBondContact O-N 3.26Å; S268-K272 WeakPolarHBondContact OG-CE 3.32Å
269R82.3Confident81.1Confident132 Ų13291.7 Ų91.750%0.49847%0.47SS..Hα-helixtrans-64.8-43.6175.8-175.6-178.3179.2-148.12.9111.8F265 A266 A267 K272 R273F265-R269 VanDerWaalsContact O-CB 3.32Å; F265-R269 WeakPolarHBondContact O-CB 3.34Å; F265-R269 PolarHBondContact O-N 3.07Å; A266-R269 PolarHBondContact O-N 3.2Å; A267-R269 VanDerWaalsContact C-N 3.33Å; A267-R269 PolarHBondContact O-N 2.6Å; R269-K272 PolarHBondContact O-N 2.73Å; R269-R273 PolarHBondContact O-N 3.02Å
270A85.5Confident81.4Confident60 Ų6089.8 Ų89.850%0.49647%0.469SS..Hα-helixtrans-63.7-48.1177.500000111.6A266 A267 K272 R273 S274A266-A270 WeakPolarHBondContact O-CB 3.15Å; A266-A270 PolarHBondContact O-N 2.86Å; A267-A270 PolarHBondContact O-N 2.95Å; A270-K272 VanDerWaalsContact C-N 3.28Å; A270-K272 PolarHBondContact O-N 2.85Å; A270-R273 PolarHBondContact O-N 3.37Å; A270-S274 PolarHBondContact O-N 2.62Å
271Y84Confident80.6Confident143 Ų14393.6 Ų93.656%0.56150%0.5SS*.Hα-helixtrans-56.5-40.2174.4170.7-99.2000112.7A267 S274 K275A267-Y271 WeakPolarHBondContact O-CB 2.98Å; A267-Y271 PolarHBondContact O-N 3.14Å; Y271-S274 PolarHBondContact O-N 3.12Å; Y271-S274 PolarHBondContact O-OG 3.42Å; Y271-K275 HydrophobicContact CE1-CD 4.21Å; Y271-K275 VanDerWaalsContact O-CB 3.31Å; Y271-K275 WeakPolarHBondContact O-CB 3.46Å; Y271-K275 PolarHBondContact O-N 2.87Å
272K79.4Confident80.5Confident23 Ų2396.7 Ų96.710%0.151%0.514CS..Hα-helixtrans-68.5-40.8177.9-73.7170.1-171.2-1730112.4H254 A256 S268 R269 A270 S274 K275 Y276H254-K272 HydrophobicContact CB-CD 4.12Å; H254-K272 VanDerWaalsContact CG-CE 3.5Å; H254-K272 WeakPolarHBondContact ND1-CE 3.23Å; H254-K272 PolarHBondContact ND1-NZ 3.04Å; A256-K272 PolarHBondContact O-NZ 3.05Å; S268-K272 WeakPolarHBondContact O-CB 3.07Å; S268-K272 WeakPolarHBondContact O-CD 3.34Å; S268-K272 WeakPolarHBondContact O-CG 3.49Å; S268-K272 PolarHBondContact O-N 3.26Å; S268-K272 WeakPolarHBondContact OG-CE 3.32Å; R269-K272 PolarHBondContact O-N 2.73Å; A270-K272 VanDerWaalsContact C-N 3.28Å; A270-K272 PolarHBondContact O-N 2.85Å; K272-S274 VanDerWaalsContact C-N 3.33Å; K272-K275 PolarHBondContact O-N 2.76Å; K272-Y276 HydrophobicContact CB-CE2 4.37Å; K272-Y276 WeakPolarHBondContact O-CD2 3.25Å; K272-Y276 PolarHBondContact O-N 2.93Å; K272-Y276 VanDerWaalsContact O-N 3.14Å
273R82.8Confident80.3Confident169 Ų16995.7 Ų95.764%0.63850%0.502SS*.Hα-helixtrans-59.5-45.1174.8-80.6-176.5165.7-175.7-7.7111R269 A270 Y276 A277R269-R273 PolarHBondContact O-N 3.02Å; A270-R273 PolarHBondContact O-N 3.37Å; R273-Y276 PolarHBondContact O-N 2.85Å; R273-A277 PolarHBondContact O-N 3.22Å
274S85.7Confident80Confident75 Ų7592.2 Ų92.252%0.52449%0.488SS..Hα-helixtrans-66.9-41.8176.962.70000112.7A270 Y271 K272 Y276 A277A270-S274 PolarHBondContact O-N 2.62Å; Y271-S274 PolarHBondContact O-N 3.12Å; Y271-S274 PolarHBondContact O-OG 3.42Å; K272-S274 VanDerWaalsContact C-N 3.33Å; S274-Y276 VanDerWaalsContact C-N 3.27Å; S274-Y276 PolarHBondContact O-N 3.45Å; S274-A277 PolarHBondContact O-N 3.27Å
275K81.9Confident80Confident76 Ų7689 Ų8933%0.3349%0.485SS..Hα-helixtrans-56.2-37.9177.2-178.4-179170.6-168.60112.9D241 Y271 K272D241-K275 IonicContact OD1-NZ 3.82Å; D241-K275 WeakPolarHBondContact OD2-CE 3.43Å; D241-K275 IonicContact OD2-NZ 3.44Å; D241-K275 PolarHBondContact OD2-NZ 2.93Å; Y271-K275 HydrophobicContact CE1-CD 4.21Å; Y271-K275 VanDerWaalsContact O-CB 3.31Å; Y271-K275 WeakPolarHBondContact O-CB 3.46Å; Y271-K275 PolarHBondContact O-N 2.87Å; K272-K275 PolarHBondContact O-N 2.76Å
276Y80.1Confident80Confident31 Ų3190.9 Ų90.912%0.12250%0.499CS..Hα-helixtrans-103.31-178.3-55.5-60.4000115.3D241 I252 H254 K272 R273 S274 V278 L279D241-Y276 PolarHBondContact OD1-OH 3.48Å; D241-Y276 PolarHBondContact OD2-OH 3.47Å; I252-Y276 HydrophobicContact CD1-CD1 3.4Å; I252-Y276 HydrophobicContact CD1-CD2 3.93Å; I252-Y276 HydrophobicContact CD1-CE1 4Å; I252-Y276 HydrophobicContact CD1-CE2 4.49Å; I252-Y276 HydrophobicContact CD1-CG 3.37Å; I252-Y276 HydrophobicContact CG2-CD1 4.29Å; I252-Y276 HydrophobicContact CG2-CD2 4.14Å; I252-Y276 HydrophobicContact CG2-CE1 3.83Å; I252-Y276 HydrophobicContact CG2-CE2 3.7Å; I252-Y276 HydrophobicContact CG2-CG 4.43Å; H254-Y276 PolarHBondContact CD2-OH 2.89Å; H254-Y276 VanDerWaalsContact CD2-OH 3.32Å; K272-Y276 HydrophobicContact CB-CE2 4.37Å; K272-Y276 WeakPolarHBondContact O-CD2 3.25Å; K272-Y276 PolarHBondContact O-N 2.93Å; K272-Y276 VanDerWaalsContact O-N 3.14Å; R273-Y276 PolarHBondContact O-N 2.85Å; S274-Y276 VanDerWaalsContact C-N 3.27Å; S274-Y276 PolarHBondContact O-N 3.45Å; Y276-V278 PolarHBondContact O-N 3Å; Y276-V278 VanDerWaalsContact O-N 3.15Å; Y276-L279 HydrophobicContact CD1-CD1 3.82Å; Y276-L279 WeakPolarHBondContact O-CB 3.1Å; Y276-L279 PolarHBondContact O-N 3.46Å
277A82.5Confident79.7Confident49 Ų4993.3 Ų93.341%0.40550%0.502SS..Hα-helixtrans-56-31174.400000111.6R273 S274 L279 E280R273-A277 PolarHBondContact O-N 3.22Å; S274-A277 PolarHBondContact O-N 3.27Å; A277-L279 PolarHBondContact O-N 2.94Å; A277-E280 PolarHBondContact O-N 2.65Å; A277-E280 VanDerWaalsContact O-N 3.15Å
278V80Confident79.3Confident130 Ų13095.4 Ų95.479%0.78850%0.5SS*.THydrogen-bonded Turntrans-65.6-17.5176.6-167.70000113.2Y276Y276-V278 PolarHBondContact O-N 3Å; Y276-V278 VanDerWaalsContact O-N 3.15Å
279L73.7Confident79.2Confident79 Ų79101.2 Ų101.241%0.41453%0.528SS..THydrogen-bonded Turntrans-95.4-5.7177.9-60.7176.9000113I243 I252 Y276 A277I243-L279 HydrophobicContact CD1-CD1 4.41Å; I252-L279 HydrophobicContact CD1-CD1 3.68Å; Y276-L279 HydrophobicContact CD1-CD1 3.82Å; Y276-L279 WeakPolarHBondContact O-CB 3.1Å; Y276-L279 PolarHBondContact O-N 3.46Å; A277-L279 PolarHBondContact O-N 2.94Å
280E70.1Confident79Confident152 Ų15298.6 Ų98.671%0.7153%0.53SS*.  trans-71124.1170.7-66.1-175166.800107.9A277A277-E280 PolarHBondContact O-N 2.65Å; A277-E280 VanDerWaalsContact O-N 3.15Å
281P62.2Low78.4Confident196 Ų196102.1 Ų102.1100%1.27353%0.533SS*.  trans-65.10-178.728.2-34.9000112.9

Retrieved 281 of 281 residues in 80.1 ms (Link to these results)