A0A077ZFR5_TRITR Loading...

Acatn domain containing protein

AlphaFold DB , UniProt , Accession A0A077ZFR5, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 502 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32	Very low	34.3	Very low	242 Å²	242	164.1 Å²	164.1	100%	1.192	83%	0.826	S	S	*	*				0	132.7	0	-85	176.5	166.8	0	0	108.5
2	P	36.8	Very low	34.2	Very low	108 Å²	108	156.4 Å²	156.4	70%	0.701	79%	0.789	S	S	*	*			trans	-84.9	156.9	-160.6	33.9	-34.1	0	0	0	114.1	Y4	P2-Y4 PolarHBondContact O-N 3.15Å; P2-Y4 VanDerWaalsContact O-N 3.15Å
3	M	31.1	Very low	34.4	Very low	193 Å²	193	154.2 Å²	154.2	95%	0.951	78%	0.781	S	S	*	*			trans	-47.6	99.6	166.8	-134.7	174.5	175.3	0	0	111.6	A5	M3-A5 PolarHBondContact O-N 3.42Å
4	Y	35.5	Very low	34.9	Very low	217 Å²	217	154.2 Å²	154.2	85%	0.851	77%	0.767	S	S	*	*			trans	-88.5	94.2	159.3	-90.2	-85.3	0	0	0	108.2	P2 K6	P2-Y4 PolarHBondContact O-N 3.15Å; P2-Y4 VanDerWaalsContact O-N 3.15Å; Y4-K6 PolarHBondContact O-N 2.89Å; Y4-K6 VanDerWaalsContact O-N 3.07Å
5	A	36.1	Very low	35.4	Very low	82 Å²	82	152.3 Å²	152.3	68%	0.678	75%	0.749	S	S	*	*			trans	-55.6	109	158.3	0	0	0	0	0	107.8	M3 K7	M3-A5 PolarHBondContact O-N 3.42Å; A5-K7 VanDerWaalsContact C-N 3.33Å; A5-K7 PolarHBondContact O-N 3.07Å
6	K	34	Very low	35.4	Very low	204 Å²	204	148.1 Å²	148.1	89%	0.887	73%	0.73	S	S	*	*			trans	-58.5	98.7	165.2	-93.2	-179.1	172.6	179.5	0	107.6	Y4 D8	Y4-K6 PolarHBondContact O-N 2.89Å; Y4-K6 VanDerWaalsContact O-N 3.07Å; K6-D8 VanDerWaalsContact C-N 3.31Å
7	K	31.3	Very low	35.6	Very low	183 Å²	183	146.4 Å²	146.4	80%	0.796	72%	0.723	S	S	*	*			trans	-97	24.1	178.9	-139.3	-178.3	-175.5	-176.4	0	112.4	A5	A5-K7 VanDerWaalsContact C-N 3.33Å; A5-K7 PolarHBondContact O-N 3.07Å
8	D	33.6	Very low	36	Very low	145 Å²	145	144.3 Å²	144.3	78%	0.775	71%	0.711	S	S	*	*			trans	-117.3	38.1	-179	-63.6	-33.1	0	0	0	112.8	K6	K6-D8 VanDerWaalsContact C-N 3.31Å
9	L	36.3	Very low	36.1	Very low	152 Å²	152	142.2 Å²	142.2	80%	0.796	71%	0.707	S	S	*	*			trans	-97.3	52	152.8	-107.1	132.5	0	0	0	108.2	L11	L9-L11 VanDerWaalsContact C-N 3.3Å; L9-L11 PolarHBondContact O-N 3Å
10	L	36	Very low	36.1	Very low	143 Å²	143	145.2 Å²	145.2	75%	0.749	71%	0.71	S	S	*	*			trans	-64.8	99.7	161.2	-72.8	165.9	0	0	0	105.7	D12	L10-D12 PolarHBondContact O-N 2.77Å
11	L	35	Very low	36.2	Very low	136 Å²	136	147.8 Å²	147.8	71%	0.712	72%	0.718	S	S	*	*			trans	-40.4	115.9	162.4	-80.3	149.2	0	0	0	107.6	L9 D13	L9-L11 VanDerWaalsContact C-N 3.3Å; L9-L11 PolarHBondContact O-N 3Å; L11-D13 PolarHBondContact O-N 2.82Å; L11-D13 VanDerWaalsContact O-N 3.12Å
12	D	32.4	Very low	36.7	Very low	72 Å²	72	143.8 Å²	143.8	39%	0.385	69%	0.689	S	S	.	*			trans	-45.4	120.1	-179.3	-165.8	-20.6	0	0	0	109	L10 R14 Y15	L10-D12 PolarHBondContact O-N 2.77Å; D12-R14 VanDerWaalsContact CG-NE 3.33Å; D12-R14 PolarHBondContact O-N 3.04Å; D12-R14 WeakPolarHBondContact OD1-CG 3.38Å; D12-R14 IonicContact OD1-CZ 3.77Å; D12-R14 PolarHBondContact OD1-N 2.81Å; D12-R14 IonicContact OD1-NE 3.02Å; D12-R14 PolarHBondContact OD1-NE 3.12Å; D12-R14 IonicContact OD1-NH2 3.73Å; D12-R14 IonicContact OD2-CZ 3.25Å; D12-R14 VanDerWaalsContact OD2-CZ 3.25Å; D12-R14 IonicContact OD2-NE 2.91Å; D12-R14 PolarHBondContact OD2-NE 2.74Å; D12-R14 IonicContact OD2-NH2 2.74Å; D12-R14 PolarHBondContact OD2-NH2 3.29Å; D12-Y15 PolarHBondContact O-N 2.81Å
13	D	37.1	Very low	37.1	Very low	127 Å²	127	142.5 Å²	142.5	68%	0.679	68%	0.683	S	S	*	*	G	3₁₀ helix	trans	-52.9	-14.4	-179.5	-84.1	-35.4	0	0	0	112.4	L11 Y15 L16	L11-D13 PolarHBondContact O-N 2.82Å; L11-D13 VanDerWaalsContact O-N 3.12Å; D13-Y15 VanDerWaalsContact C-N 3.25Å; D13-Y15 PolarHBondContact O-N 2.91Å; D13-L16 WeakPolarHBondContact O-CB 3.46Å; D13-L16 PolarHBondContact O-N 3.43Å; D13-L16 WeakPolarHBondContact OD1-CD1 3.46Å
14	R	41.5	Very low	38	Very low	155 Å²	155	142.5 Å²	142.5	59%	0.585	68%	0.678	S	S	*	*	G	3₁₀ helix	trans	-62.7	-23.6	171.8	-69.7	-174.6	-82.1	-151.6	1.2	114.4	D12	D12-R14 VanDerWaalsContact CG-NE 3.33Å; D12-R14 PolarHBondContact O-N 3.04Å; D12-R14 WeakPolarHBondContact OD1-CG 3.38Å; D12-R14 IonicContact OD1-CZ 3.77Å; D12-R14 PolarHBondContact OD1-N 2.81Å; D12-R14 IonicContact OD1-NE 3.02Å; D12-R14 PolarHBondContact OD1-NE 3.12Å; D12-R14 IonicContact OD1-NH2 3.73Å; D12-R14 IonicContact OD2-CZ 3.25Å; D12-R14 VanDerWaalsContact OD2-CZ 3.25Å; D12-R14 IonicContact OD2-NE 2.91Å; D12-R14 PolarHBondContact OD2-NE 2.74Å; D12-R14 IonicContact OD2-NH2 2.74Å; D12-R14 PolarHBondContact OD2-NH2 3.29Å
15	Y	41.7	Very low	39.1	Very low	126 Å²	126	133.8 Å²	133.8	49%	0.494	65%	0.647	S	S	.	*	G	3₁₀ helix	trans	-81.9	-19.5	169.8	-75.7	-82.7	0	0	0	113	D12 D13 L17	D12-Y15 PolarHBondContact O-N 2.81Å; D13-Y15 VanDerWaalsContact C-N 3.25Å; D13-Y15 PolarHBondContact O-N 2.91Å; Y15-L17 VanDerWaalsContact C-N 3.29Å; Y15-L17 PolarHBondContact O-N 3.02Å
16	L	36.1	Very low	40.6	Very low	85 Å²	85	132.2 Å²	132.2	45%	0.445	63%	0.631	S	S	.	*	G	3₁₀ helix	trans	-81	-2.7	178.2	-77.3	167.2	0	0	0	114	D13 H18 T19	D13-L16 WeakPolarHBondContact O-CB 3.46Å; D13-L16 PolarHBondContact O-N 3.43Å; D13-L16 WeakPolarHBondContact OD1-CD1 3.46Å; L16-H18 PolarHBondContact O-N 3.41Å; L16-T19 HydrophobicContact CD2-CG2 4.01Å; L16-T19 PolarHBondContact O-N 2.95Å; L16-T19 PolarHBondContact O-OG1 3.44Å
17	L	38.9	Very low	42.3	Very low	119 Å²	119	126.3 Å²	126.3	62%	0.623	61%	0.608	S	S	*	*	G	3₁₀ helix	trans	-51.8	-22.5	171.3	-94.4	155.9	0	0	0	113.1	Y15	Y15-L17 VanDerWaalsContact C-N 3.29Å; Y15-L17 PolarHBondContact O-N 3.02Å
18	H	43	Very low	44.2	Very low	109 Å²	109	126.2 Å²	126.2	51%	0.505	61%	0.608	S	S	.	*	G	3₁₀ helix	trans	-83.7	-7.7	176.4	-66.7	-55.3	0	0	0	115.7	L16	L16-H18 PolarHBondContact O-N 3.41Å
19	T	38	Very low	46.3	Very low	104 Å²	104	125.1 Å²	125.1	64%	0.638	60%	0.598	S	S	*	*	G	3₁₀ helix	trans	-98.9	-2.6	175.9	58.8	0	0	0	0	113.7	L16 K21	L16-T19 HydrophobicContact CD2-CG2 4.01Å; L16-T19 PolarHBondContact O-N 2.95Å; L16-T19 PolarHBondContact O-OG1 3.44Å; T19-K21 PolarHBondContact O-N 3.34Å
20	R	35.1	Very low	48.6	Very low	202 Å²	202	118.2 Å²	118.2	76%	0.762	56%	0.562	S	S	*	*	S	Bend	trans	-59.9	117	172.5	-150.1	175.9	-170.1	177.9	2.6	107.6	R22	R20-R22 PolarHBondContact O-N 3.01Å; R20-R22 VanDerWaalsContact O-N 3.07Å
21	K	38.3	Very low	51.1	Low	200 Å²	200	117 Å²	117	87%	0.87	56%	0.556	S	S	*	*			trans	-39.1	121	169.6	-80.3	177.9	175.8	175.4	0	107.6	T19 S23	T19-K21 PolarHBondContact O-N 3.34Å; K21-S23 VanDerWaalsContact C-N 3.3Å; K21-S23 PolarHBondContact O-N 2.92Å
22	R	42	Very low	53.8	Low	158 Å²	158	117.4 Å²	117.4	60%	0.596	56%	0.558	S	S	*	*			trans	-39.8	93.8	178.3	-82	-178.9	168.6	172.2	-5.6	109.8	R20 K24 E169	R20-R22 PolarHBondContact O-N 3.01Å; R20-R22 VanDerWaalsContact O-N 3.07Å; R22-K24 PolarHBondContact O-N 2.82Å; R22-E169 HydrophobicContact CG-CG 4.03Å
23	S	46.2	Very low	56.7	Low	80 Å²	80	115.4 Å²	115.4	56%	0.559	55%	0.547	S	S	*	.			trans	-66.2	119.8	156.4	176.2	0	0	0	0	102.6	K21 T25	K21-S23 VanDerWaalsContact C-N 3.3Å; K21-S23 PolarHBondContact O-N 2.92Å; S23-T25 PolarHBondContact O-N 3.2Å
24	K	49.7	Very low	59.3	Low	194 Å²	194	110.7 Å²	110.7	84%	0.843	52%	0.523	S	S	*	.			trans	-66.1	83.1	171.6	-73	-178.4	179.3	177.2	0	106.5	R22 S26	R22-K24 PolarHBondContact O-N 2.82Å; K24-S26 PolarHBondContact O-N 3.01Å; K24-S26 VanDerWaalsContact O-N 3.14Å
25	T	58.4	Low	61.9	Low	33 Å²	33	105.3 Å²	105.3	20%	0.202	52%	0.516	C	S	.	.			trans	-53.8	120.7	163.3	40.1	0	0	0	0	105.5	S23 E29 E169	S23-T25 PolarHBondContact O-N 3.2Å; T25-E29 WeakPolarHBondContact CG2-OE2 3.42Å; T25-E169 PolarHBondContact OG1-OE2 3.48Å
26	S	67.5	Low	64.4	Low	49 Å²	49	101.1 Å²	101.1	34%	0.343	50%	0.502	S	S	.	.			trans	-67.6	143.3	-175.4	74.7	0	0	0	0	108.1	K24 K28 E29	K24-S26 PolarHBondContact O-N 3.01Å; K24-S26 VanDerWaalsContact O-N 3.14Å; S26-K28 PolarHBondContact O-N 2.58Å; S26-K28 WeakPolarHBondContact OG-CB 3.42Å; S26-E29 PolarHBondContact N-OE1 2.87Å; S26-E29 WeakPolarHBondContact O-CB 3.36Å; S26-E29 PolarHBondContact O-N 3.44Å
27	L	69.3	Low	67.3	Low	80 Å²	80	97.1 Å²	97.1	42%	0.419	48%	0.481	S	S	.	.	T	Hydrogen-bonded Turn	trans	-51.7	-22.3	173.2	-175.5	67.4	0	0	0	112.1	E29 D30 L31 Y173	L27-E29 VanDerWaalsContact C-N 3.32Å; L27-E29 PolarHBondContact O-N 2.83Å; L27-D30 CarbonylContact O-C 3.59Å; L27-D30 PolarHBondContact O-N 2.95Å; L27-L31 PolarHBondContact O-N 3.14Å; L27-Y173 HydrophobicContact CD1-CD2 4.32Å; L27-Y173 HydrophobicContact CD1-CE2 4.25Å
28	K	72.7	Confident	70	Confident	181 Å²	181	93.5 Å²	93.5	79%	0.787	46%	0.464	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.1	-34.6	175.1	-57.5	-175.8	175.9	-176.4	0	112.8	S26 D30 L31	S26-K28 PolarHBondContact O-N 2.58Å; S26-K28 WeakPolarHBondContact OG-CB 3.42Å; K28-D30 VanDerWaalsContact C-N 3.33Å; K28-L31 WeakPolarHBondContact O-CB 3.38Å; K28-L31 PolarHBondContact O-N 3.38Å
29	E	76	Confident	72.6	Confident	123 Å²	123	92 Å²	92	58%	0.575	46%	0.456	S	S	*	.	T	Hydrogen-bonded Turn	trans	-68.8	-35.7	176.8	-69.6	163.7	-139.5	0	0	111.2	T25 S26 L27	T25-E29 WeakPolarHBondContact CG2-OE2 3.42Å; S26-E29 PolarHBondContact N-OE1 2.87Å; S26-E29 WeakPolarHBondContact O-CB 3.36Å; S26-E29 PolarHBondContact O-N 3.44Å; L27-E29 VanDerWaalsContact C-N 3.32Å; L27-E29 PolarHBondContact O-N 2.83Å
30	D	86.4	Confident	75.4	Confident	7 Å²	7	87 Å²	87	4%	0.037	43%	0.426	C	S	.	.	T	Hydrogen-bonded Turn	trans	-87.7	0.6	177	-80.9	-26.4	0	0	0	113.6	L27 K28 L32 N33 T34 L166 S167 N170	L27-D30 CarbonylContact O-C 3.59Å; L27-D30 PolarHBondContact O-N 2.95Å; K28-D30 VanDerWaalsContact C-N 3.33Å; D30-L32 PolarHBondContact O-N 3.01Å; D30-N33 PolarHBondContact O-N 3.08Å; D30-T34 VanDerWaalsContact O-CB 3.3Å; D30-T34 WeakPolarHBondContact O-CB 3.49Å; D30-T34 PolarHBondContact O-N 3.08Å; D30-T34 PolarHBondContact O-OG1 2.91Å; D30-L166 HydrophobicContact CB-CD2 4.28Å; D30-S167 PolarHBondContact OD1-N 3.02Å; D30-S167 PolarHBondContact OD1-OG 3.42Å; D30-S167 WeakPolarHBondContact OD2-CB 3.4Å; D30-S167 PolarHBondContact OD2-N 2.78Å; D30-S167 PolarHBondContact OD2-OG 3.16Å; D30-N170 WeakPolarHBondContact OD2-CB 3.4Å; D30-N170 PolarHBondContact OD2-ND2 3.14Å
31	L	88.7	Confident	78.4	Confident	116 Å²	116	77.6 Å²	77.6	61%	0.607	39%	0.39	S	S	*	.	H	α-helix	trans	-61.6	-42.4	-171.8	-174.9	65.7	0	0	0	112.3	L27 K28 T34 G35	L27-L31 PolarHBondContact O-N 3.14Å; K28-L31 WeakPolarHBondContact O-CB 3.38Å; K28-L31 PolarHBondContact O-N 3.38Å; L31-T34 PolarHBondContact O-N 3.1Å; L31-G35 PolarHBondContact O-N 2.95Å
32	L	91.2	Very high	81.2	Confident	146 Å²	146	69.5 Å²	69.5	76%	0.764	36%	0.356	S	S	*	.	H	α-helix	trans	-65.5	-42.7	177.6	-177	67	0	0	0	111.5	D30 G35 L36	D30-L32 PolarHBondContact O-N 3.01Å; L32-G35 PolarHBondContact O-N 3.21Å; L32-L36 WeakPolarHBondContact O-CB 3.39Å; L32-L36 PolarHBondContact O-N 3.27Å
33	N	92.4	Very high	83.8	Confident	30 Å²	30	62 Å²	62	16%	0.16	33%	0.328	C	S	.	.	H	α-helix	trans	-65.4	-42	177.3	-70.6	-27.5	0	0	0	111.4	D30 L36 L37 M165 L166 K247	D30-N33 PolarHBondContact O-N 3.08Å; N33-L36 PolarHBondContact O-N 3.4Å; N33-L37 WeakPolarHBondContact O-CB 3.5Å; N33-L37 WeakPolarHBondContact O-CG 3.42Å; N33-L37 PolarHBondContact O-N 3.4Å; N33-M165 HydrophobicContact CB-CG 3.78Å; N33-M165 HydrophobicContact CB-SD 3.9Å; N33-M165 PolarHBondContact ND2-O 3.5Å; N33-L166 HydrophobicContact CB-CD2 4.33Å; N33-K247 PolarHBondContact OD1-NZ 3.1Å
34	T	93.1	Very high	86.1	Confident	27 Å²	27	58.2 Å²	58.2	17%	0.166	30%	0.301	C	S	.	.	H	α-helix	trans	-62.3	-47.9	176	-56.4	0	0	0	0	110.5	D30 L31 L36 L37 V38	D30-T34 VanDerWaalsContact O-CB 3.3Å; D30-T34 WeakPolarHBondContact O-CB 3.49Å; D30-T34 PolarHBondContact O-N 3.08Å; D30-T34 PolarHBondContact O-OG1 2.91Å; L31-T34 PolarHBondContact O-N 3.1Å; T34-L36 PolarHBondContact O-N 2.99Å; T34-L37 PolarHBondContact O-N 3.49Å; T34-V38 WeakPolarHBondContact O-CG2 3.42Å; T34-V38 PolarHBondContact O-N 3.22Å
35	G	94.4	Very high	88.3	Confident	43 Å²	43	49 Å²	49	44%	0.443	26%	0.261	S	S	.	.	H	α-helix	trans	-61	-42.8	176.5	0	0	0	0	0	112.6	L31 L32 F39	L31-G35 PolarHBondContact O-N 2.95Å; L32-G35 PolarHBondContact O-N 3.21Å; G35-F39 WeakPolarHBondContact O-CB 3.48Å; G35-F39 PolarHBondContact O-N 3.39Å
36	L	95.5	Very high	90	Very high	38 Å²	38	47.4 Å²	47.4	20%	0.199	25%	0.251	C	S	.	.	H	α-helix	trans	-61.7	-44.8	174.2	178	60.2	0	0	0	111.6	L32 N33 T34 F39 L40 M165 V243 K247	L32-L36 WeakPolarHBondContact O-CB 3.39Å; L32-L36 PolarHBondContact O-N 3.27Å; N33-L36 PolarHBondContact O-N 3.4Å; T34-L36 PolarHBondContact O-N 2.99Å; L36-F39 PolarHBondContact O-N 2.88Å; L36-L40 HydrophobicContact CD1-CD1 4.21Å; L36-L40 HydrophobicContact CD1-CD2 4.48Å; L36-L40 HydrophobicContact CD1-CG 4.06Å; L36-L40 HydrophobicContact CG-CD1 4.04Å; L36-L40 HydrophobicContact CG-CG 4.33Å; L36-L40 VanDerWaalsContact O-CG 3.3Å; L36-L40 WeakPolarHBondContact O-CG 3.42Å; L36-L40 PolarHBondContact O-N 3.25Å; L36-M165 HydrophobicContact CD2-CE 4.05Å; L36-M165 HydrophobicContact CD2-SD 4.06Å; L36-M165 HydrophobicContact CG-SD 4.46Å; L36-V243 HydrophobicContact CD1-CG2 3.93Å; L36-K247 HydrophobicContact CD2-CD 4.11Å; L36-K247 HydrophobicContact CD2-CG 4.22Å
37	L	95.6	Very high	91.3	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-62	-49	178.4	-76.6	173.1	0	0	0	112.2	N33 T34 F39 L40 Y41 V158 A162 M165 L166 C177	N33-L37 WeakPolarHBondContact O-CB 3.5Å; N33-L37 WeakPolarHBondContact O-CG 3.42Å; N33-L37 PolarHBondContact O-N 3.4Å; T34-L37 PolarHBondContact O-N 3.49Å; L37-F39 PolarHBondContact O-N 3.2Å; L37-L40 PolarHBondContact O-N 3.2Å; L37-L40 VanDerWaalsContact O-N 3.17Å; L37-Y41 HydrophobicContact CB-CD2 4.45Å; L37-Y41 HydrophobicContact CB-CE2 4.33Å; L37-Y41 HydrophobicContact CD2-CE2 4.49Å; L37-Y41 WeakPolarHBondContact O-CD2 3.5Å; L37-Y41 PolarHBondContact O-N 3.26Å; L37-V158 HydrophobicContact CD2-CG1 4.2Å; L37-A162 HydrophobicContact CD1-CB 3.91Å; L37-A162 HydrophobicContact CD2-CB 3.88Å; L37-M165 HydrophobicContact CD1-SD 4.27Å; L37-M165 HydrophobicContact CD2-CE 3.84Å; L37-M165 HydrophobicContact CD2-SD 4.01Å; L37-M165 HydrophobicContact CG-CE 4.23Å; L37-M165 HydrophobicContact CG-SD 3.73Å; L37-L166 HydrophobicContact CD1-CD1 3.8Å; L37-L166 HydrophobicContact CD1-CD2 3.9Å; L37-L166 HydrophobicContact CD1-CG 3.62Å; L37-C177 HydrophobicContact CB-CB 4.08Å
38	V	96.6	Very high	92.4	Very high	43 Å²	43	42.8 Å²	42.8	26%	0.261	22%	0.223	S	C	.	.	H	α-helix	trans	-53.7	-44	175.5	171.8	0	0	0	0	110.4	T34 Y41 L42 C177 V180 G181	T34-V38 WeakPolarHBondContact O-CG2 3.42Å; T34-V38 PolarHBondContact O-N 3.22Å; V38-Y41 PolarHBondContact O-N 3.03Å; V38-L42 WeakPolarHBondContact O-CB 3.42Å; V38-L42 PolarHBondContact O-N 3.16Å; V38-C177 HydrophobicContact CG2-CB 3.88Å; V38-V180 HydrophobicContact CG1-CG1 4.32Å; V38-G181 WeakPolarHBondContact O-CA 3.45Å
39	F	97.5	Very high	93.3	Very high	77 Å²	77	34.2 Å²	34.2	34%	0.338	19%	0.186	S	C	.	.	H	α-helix	trans	-68.2	-41.2	179.2	-177.9	-111.1	0	0	0	113.1	G35 L36 L37 Y41 L42 L43 V235	G35-F39 WeakPolarHBondContact O-CB 3.48Å; G35-F39 PolarHBondContact O-N 3.39Å; L36-F39 PolarHBondContact O-N 2.88Å; L37-F39 PolarHBondContact O-N 3.2Å; F39-Y41 VanDerWaalsContact C-N 3.35Å; F39-Y41 PolarHBondContact O-N 2.86Å; F39-L42 WeakPolarHBondContact O-CB 3.35Å; F39-L42 PolarHBondContact O-N 3.04Å; F39-L43 HydrophobicContact CD1-CD1 4.24Å; F39-L43 HydrophobicContact CE1-CD1 3.74Å; F39-L43 HydrophobicContact CE1-CG 4.21Å; F39-L43 HydrophobicContact CE2-CD2 4.34Å; F39-L43 HydrophobicContact CE2-CG 4.45Å; F39-L43 HydrophobicContact CZ-CD1 4.04Å; F39-L43 HydrophobicContact CZ-CD2 4.05Å; F39-L43 HydrophobicContact CZ-CG 4.13Å; F39-L43 WeakPolarHBondContact O-CG 3.49Å; F39-L43 PolarHBondContact O-N 3.47Å; F39-V235 HydrophobicContact CZ-CG1 4.03Å
40	L	97.4	Very high	94	Very high	1 Å²	1	28.6 Å²	28.6	1%	0.005	16%	0.16	C	C	.	.	H	α-helix	trans	-62.7	-41.1	175.5	-70.7	174.9	0	0	0	111.9	L36 L37 L43 Q44 L103 V158 W161	L36-L40 HydrophobicContact CD1-CD1 4.21Å; L36-L40 HydrophobicContact CD1-CD2 4.48Å; L36-L40 HydrophobicContact CD1-CG 4.06Å; L36-L40 HydrophobicContact CG-CD1 4.04Å; L36-L40 HydrophobicContact CG-CG 4.33Å; L36-L40 VanDerWaalsContact O-CG 3.3Å; L36-L40 WeakPolarHBondContact O-CG 3.42Å; L36-L40 PolarHBondContact O-N 3.25Å; L37-L40 PolarHBondContact O-N 3.2Å; L37-L40 VanDerWaalsContact O-N 3.17Å; L40-L43 PolarHBondContact O-N 3.17Å; L40-Q44 PolarHBondContact O-N 3.48Å; L40-Q44 VanDerWaalsContact O-N 3.08Å; L40-L103 HydrophobicContact CD1-CD2 4.3Å; L40-L103 HydrophobicContact CD2-CD2 4.27Å; L40-V158 HydrophobicContact CB-CG1 3.9Å; L40-V158 HydrophobicContact CB-CG2 4.09Å; L40-V158 HydrophobicContact CD1-CG1 4.48Å; L40-V158 HydrophobicContact CD1-CG2 4.47Å; L40-W161 HydrophobicContact CD1-CE3 3.89Å; L40-W161 HydrophobicContact CD1-CZ3 3.8Å
41	Y	97.6	Very high	94.2	Very high	3 Å²	3	28.3 Å²	28.3	1%	0.012	16%	0.158	C	C	.	.	H	α-helix	trans	-67.9	-34.2	173.7	-71.6	-59	0	0	0	112.4	L37 V38 F39 Q44 G45 V158 D159 C177 N178 Q182	L37-Y41 HydrophobicContact CB-CD2 4.45Å; L37-Y41 HydrophobicContact CB-CE2 4.33Å; L37-Y41 HydrophobicContact CD2-CE2 4.49Å; L37-Y41 WeakPolarHBondContact O-CD2 3.5Å; L37-Y41 PolarHBondContact O-N 3.26Å; V38-Y41 PolarHBondContact O-N 3.03Å; F39-Y41 VanDerWaalsContact C-N 3.35Å; F39-Y41 PolarHBondContact O-N 2.86Å; Y41-Q44 WeakPolarHBondContact O-CB 3.34Å; Y41-Q44 PolarHBondContact O-N 3.41Å; Y41-G45 PolarHBondContact O-N 3.05Å; Y41-V158 HydrophobicContact CD1-CB 4.43Å; Y41-V158 HydrophobicContact CD1-CG1 3.75Å; Y41-V158 HydrophobicContact CD2-CG1 4.24Å; Y41-V158 HydrophobicContact CE1-CB 4.03Å; Y41-V158 HydrophobicContact CE1-CG1 3.45Å; Y41-V158 VanDerWaalsContact CE1-CG1 3.45Å; Y41-V158 HydrophobicContact CE2-CG1 3.99Å; Y41-V158 HydrophobicContact CG-CG1 4.13Å; Y41-D159 WeakPolarHBondContact CE1-OD1 3.43Å; Y41-D159 WeakPolarHBondContact OH-CA 3.4Å; Y41-D159 PolarHBondContact OH-OD1 3.13Å; Y41-C177 VanDerWaalsContact CD2-C 3.43Å; Y41-C177 HydrophobicContact CD2-CB 3.96Å; Y41-C177 WeakPolarHBondContact CD2-O 3.5Å; Y41-C177 HydrophobicContact CE2-CB 3.95Å; Y41-N178 HydrophobicContact CD1-CB 4.2Å; Y41-N178 HydrophobicContact CD2-CB 4.14Å; Y41-N178 HydrophobicContact CE1-CB 3.91Å; Y41-N178 WeakPolarHBondContact CE1-ND2 3.38Å; Y41-N178 HydrophobicContact CE2-CB 3.83Å; Y41-N178 HydrophobicContact CG-CB 4.31Å; Y41-Q182 WeakPolarHBondContact O-CA 3.41Å; Y41-Q182 PolarHBondContact O-N 2.85Å
42	L	97.5	Very high	94.2	Very high	31 Å²	31	23.3 Å²	23.3	16%	0.162	13%	0.133	C	C	.	.	H	α-helix	trans	-60.1	-48.6	171	-178.1	157.9	0	0	0	111.1	V38 F39 Q44 G45 I46 G181 A184 G185 L188 W232	V38-L42 WeakPolarHBondContact O-CB 3.42Å; V38-L42 PolarHBondContact O-N 3.16Å; F39-L42 WeakPolarHBondContact O-CB 3.35Å; F39-L42 PolarHBondContact O-N 3.04Å; L42-Q44 PolarHBondContact O-N 3.1Å; L42-G45 PolarHBondContact O-N 3.43Å; L42-I46 HydrophobicContact CD2-CG1 4.37Å; L42-I46 PolarHBondContact O-N 3.26Å; L42-G181 WeakPolarHBondContact CA-O 3.29Å; L42-A184 HydrophobicContact CD1-CB 4.29Å; L42-G185 VanDerWaalsContact O-CA 3.31Å; L42-G185 WeakPolarHBondContact O-CA 3.32Å; L42-L188 HydrophobicContact CD1-CD1 4.29Å; L42-L188 HydrophobicContact CD2-CD1 4.31Å; L42-L188 HydrophobicContact CG-CD1 4.43Å; L42-W232 HydrophobicContact CD2-CH2 3.85Å; L42-W232 HydrophobicContact CD2-CZ3 3.95Å
43	L	97.2	Very high	93.8	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-57.5	-40.9	176.4	-67.9	179.3	0	0	0	111.3	F39 L40 G45 I46 P47 W232 V235 F236 S239	F39-L43 HydrophobicContact CD1-CD1 4.24Å; F39-L43 HydrophobicContact CE1-CD1 3.74Å; F39-L43 HydrophobicContact CE1-CG 4.21Å; F39-L43 HydrophobicContact CE2-CD2 4.34Å; F39-L43 HydrophobicContact CE2-CG 4.45Å; F39-L43 HydrophobicContact CZ-CD1 4.04Å; F39-L43 HydrophobicContact CZ-CD2 4.05Å; F39-L43 HydrophobicContact CZ-CG 4.13Å; F39-L43 WeakPolarHBondContact O-CG 3.49Å; F39-L43 PolarHBondContact O-N 3.47Å; L40-L43 PolarHBondContact O-N 3.17Å; L43-G45 VanDerWaalsContact C-N 3.35Å; L43-G45 PolarHBondContact O-N 3.09Å; L43-I46 PolarHBondContact O-N 2.83Å; L43-P47 WeakPolarHBondContact O-CD 3.47Å; L43-W232 HydrophobicContact CD2-CE3 4.31Å; L43-W232 HydrophobicContact CD2-CZ3 4.09Å; L43-V235 HydrophobicContact CD2-CG1 3.87Å; L43-F236 HydrophobicContact CB-CE1 4Å; L43-F236 HydrophobicContact CB-CE2 4.26Å; L43-F236 HydrophobicContact CB-CZ 3.73Å; L43-F236 HydrophobicContact CD2-CD2 4.17Å; L43-F236 HydrophobicContact CD2-CE2 3.93Å; L43-F236 HydrophobicContact CD2-CZ 4.25Å; L43-F236 HydrophobicContact CG-CZ 4.48Å; L43-F236 VanDerWaalsContact O-CZ 3.26Å; L43-F236 WeakPolarHBondContact O-CZ 3.48Å; L43-S239 WeakPolarHBondContact CD1-OG 3.48Å
44	Q	94.4	Very high	93.3	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-65.2	-34.6	176.1	-174.6	-160.9	-40.5	0	0	113.6	L40 Y41 L42 I46 P47 D155	L40-Q44 PolarHBondContact O-N 3.48Å; L40-Q44 VanDerWaalsContact O-N 3.08Å; Y41-Q44 WeakPolarHBondContact O-CB 3.34Å; Y41-Q44 PolarHBondContact O-N 3.41Å; L42-Q44 PolarHBondContact O-N 3.1Å; Q44-I46 VanDerWaalsContact C-N 3.28Å; Q44-I46 PolarHBondContact O-N 3.3Å; Q44-P47 WeakPolarHBondContact O-CD 3.24Å; Q44-D155 VanDerWaalsContact CD-CB 3.46Å; Q44-D155 VanDerWaalsContact CD-OD1 3.28Å; Q44-D155 HydrophobicContact CG-CB 4.28Å; Q44-D155 VanDerWaalsContact NE2-CB 3.26Å; Q44-D155 PolarHBondContact NE2-OD1 3.12Å; Q44-D155 PolarHBondContact OE1-OD1 2.8Å
45	G	95.2	Very high	92.7	Very high	0 Å²	0	16 Å²	16	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-65.2	-29.7	176.7	0	0	0	0	0	113.3	Y41 L42 L43 L48 G49 G185 Y186	Y41-G45 PolarHBondContact O-N 3.05Å; L42-G45 PolarHBondContact O-N 3.43Å; L43-G45 VanDerWaalsContact C-N 3.35Å; L43-G45 PolarHBondContact O-N 3.09Å; G45-L48 WeakPolarHBondContact O-CB 3.12Å; G45-L48 PolarHBondContact O-N 3.17Å; G45-G49 PolarHBondContact O-N 3.09Å; G45-G185 CarbonylContact C-O 3.5Å; G45-G185 CarbonylContact O-C 3.54Å; G45-Y186 VanDerWaalsContact O-CA 3.3Å; G45-Y186 WeakPolarHBondContact O-CA 3.27Å; G45-Y186 PolarHBondContact O-N 3.33Å
46	I	94.8	Very high	91.7	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-62	-53.5	-177.7	-61.1	-75	0	0	0	112	L42 L43 Q44 L48 G49 L50 M114 G185 L188 W232	L42-I46 HydrophobicContact CD2-CG1 4.37Å; L42-I46 PolarHBondContact O-N 3.26Å; L43-I46 PolarHBondContact O-N 2.83Å; Q44-I46 VanDerWaalsContact C-N 3.28Å; Q44-I46 PolarHBondContact O-N 3.3Å; I46-L48 VanDerWaalsContact C-N 3.28Å; I46-L48 PolarHBondContact O-N 2.65Å; I46-G49 PolarHBondContact O-N 3.34Å; I46-L50 HydrophobicContact CG2-CD1 3.8Å; I46-L50 HydrophobicContact CG2-CG 4.3Å; I46-L50 WeakPolarHBondContact O-CB 3.43Å; I46-L50 WeakPolarHBondContact O-CG 3.37Å; I46-L50 PolarHBondContact O-N 3.03Å; I46-M114 HydrophobicContact CB-CE 4.37Å; I46-M114 HydrophobicContact CG2-CE 3.63Å; I46-G185 WeakPolarHBondContact CD1-O 3.29Å; I46-L188 HydrophobicContact CD1-CB 3.35Å; I46-L188 HydrophobicContact CD1-CD1 4.15Å; I46-L188 HydrophobicContact CD1-CG 4.39Å; I46-W232 HydrophobicContact CD1-CD2 4.06Å; I46-W232 HydrophobicContact CD1-CE3 4.3Å; I46-W232 HydrophobicContact CD1-CH2 3.68Å; I46-W232 HydrophobicContact CD1-CZ2 3.38Å; I46-W232 HydrophobicContact CD1-CZ3 4.12Å; I46-W232 HydrophobicContact CG1-CD2 4.21Å; I46-W232 HydrophobicContact CG1-CE3 4.1Å; I46-W232 HydrophobicContact CG1-CH2 4.1Å; I46-W232 HydrophobicContact CG1-CZ2 4.2Å; I46-W232 HydrophobicContact CG1-CZ3 4.04Å; I46-W232 HydrophobicContact CG2-CD2 4.19Å; I46-W232 HydrophobicContact CG2-CG 4.15Å
47	P	93.4	Very high	90.5	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-54	-40.6	173.5	-29.8	34.5	0	0	0	114.7	L43 Q44 T51 I110 M114 F147 A151 F236	L43-P47 WeakPolarHBondContact O-CD 3.47Å; Q44-P47 WeakPolarHBondContact O-CD 3.24Å; P47-T51 WeakPolarHBondContact O-CB 3.14Å; P47-T51 PolarHBondContact O-N 3.01Å; P47-T51 PolarHBondContact O-OG1 2.96Å; P47-I110 HydrophobicContact CG-CG2 3.87Å; P47-M114 HydrophobicContact CG-CE 3.91Å; P47-F147 VanDerWaalsContact CA-CE1 3.42Å; P47-F147 HydrophobicContact CB-CD1 4.14Å; P47-F147 HydrophobicContact CB-CE1 3.53Å; P47-F147 HydrophobicContact CB-CE2 4.12Å; P47-F147 HydrophobicContact CB-CZ 3.51Å; P47-F147 HydrophobicContact CG-CE1 4.32Å; P47-F147 HydrophobicContact CG-CE2 4.2Å; P47-F147 HydrophobicContact CG-CZ 3.8Å; P47-A151 HydrophobicContact CB-CB 3.7Å; P47-A151 HydrophobicContact CG-CB 4.13Å; P47-F236 HydrophobicContact CG-CZ 4.36Å
48	L	92.7	Very high	89.3	Confident	33 Å²	33	18.3 Å²	18.3	17%	0.173	10%	0.098	C	C	.	.	H	α-helix	trans	-62.8	-48.4	177.6	-77.5	169.8	0	0	0	111	G45 I46 T51 A52 F78 Q182 Y186	G45-L48 WeakPolarHBondContact O-CB 3.12Å; G45-L48 PolarHBondContact O-N 3.17Å; I46-L48 VanDerWaalsContact C-N 3.28Å; I46-L48 PolarHBondContact O-N 2.65Å; L48-T51 PolarHBondContact O-N 3.45Å; L48-A52 WeakPolarHBondContact O-CB 3.21Å; L48-A52 PolarHBondContact O-N 2.91Å; L48-F78 HydrophobicContact CD1-CE1 3.92Å; L48-F78 HydrophobicContact CD1-CE2 4.45Å; L48-F78 HydrophobicContact CD1-CZ 3.78Å; L48-F78 HydrophobicContact CD2-CD1 4.24Å; L48-F78 HydrophobicContact CD2-CD2 3.56Å; L48-F78 HydrophobicContact CD2-CE1 3.94Å; L48-F78 HydrophobicContact CD2-CE2 3.21Å; L48-F78 HydrophobicContact CD2-CG 4.06Å; L48-F78 HydrophobicContact CD2-CZ 3.42Å; L48-F78 VanDerWaalsContact CD2-CZ 3.42Å; L48-F78 HydrophobicContact CG-CE1 4.21Å; L48-F78 HydrophobicContact CG-CE2 3.84Å; L48-F78 HydrophobicContact CG-CZ 3.6Å; L48-Q182 HydrophobicContact CD1-CG 4.07Å; L48-Y186 HydrophobicContact CB-CD2 4.15Å
49	G	92.3	Very high	87.9	Confident	0 Å²	0	20.8 Å²	20.8	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-61.7	-45.3	177.8	0	0	0	0	0	112.6	G45 I46 T51 A52 S53 G189 N190	G45-G49 PolarHBondContact O-N 3.09Å; I46-G49 PolarHBondContact O-N 3.34Å; G49-T51 PolarHBondContact O-N 2.88Å; G49-A52 CarbonylContact O-C 3.42Å; G49-A52 PolarHBondContact O-N 3.03Å; G49-A52 VanDerWaalsContact O-N 3.13Å; G49-S53 PolarHBondContact O-N 3.19Å; G49-G189 CarbonylContact C-O 3.54Å; G49-N190 WeakPolarHBondContact O-CB 3.36Å; G49-N190 PolarHBondContact O-ND2 3.21Å
50	L	90.5	Very high	86.3	Confident	6 Å²	6	23.6 Å²	23.6	3%	0.031	13%	0.126	C	C	.	.	H	α-helix	trans	-62	-41.7	177.3	-74.3	170.4	0	0	0	111.7	I46 A52 S53 I54 M114 F147 G189 F193 L229	I46-L50 HydrophobicContact CG2-CD1 3.8Å; I46-L50 HydrophobicContact CG2-CG 4.3Å; I46-L50 WeakPolarHBondContact O-CB 3.43Å; I46-L50 WeakPolarHBondContact O-CG 3.37Å; I46-L50 PolarHBondContact O-N 3.03Å; L50-A52 VanDerWaalsContact C-N 3.3Å; L50-A52 PolarHBondContact O-N 3.44Å; L50-S53 PolarHBondContact O-N 3.48Å; L50-S53 PolarHBondContact O-OG 3.31Å; L50-I54 WeakPolarHBondContact O-CG1 3.42Å; L50-M114 HydrophobicContact CD1-CE 3.95Å; L50-F147 HydrophobicContact CB-CE1 4.32Å; L50-F147 HydrophobicContact CD1-CE1 4.36Å; L50-F147 HydrophobicContact CD1-CZ 4.25Å; L50-G189 VanDerWaalsContact CA-O 3.3Å; L50-G189 WeakPolarHBondContact CA-O 3.39Å; L50-G189 WeakPolarHBondContact CD2-O 3.49Å; L50-G189 PolarHBondContact N-O 3.21Å; L50-G189 VanDerWaalsContact N-O 3.14Å; L50-F193 HydrophobicContact CD2-CB 4.42Å; L50-F193 HydrophobicContact CD2-CD1 4.11Å; L50-F193 HydrophobicContact CD2-CD2 3.92Å; L50-F193 HydrophobicContact CD2-CE1 4.36Å; L50-F193 HydrophobicContact CD2-CE2 4.16Å; L50-F193 HydrophobicContact CD2-CG 3.88Å; L50-F193 HydrophobicContact CD2-CZ 4.38Å; L50-L229 HydrophobicContact CD1-CD2 3.71Å; L50-L229 HydrophobicContact CD2-CD2 3.95Å
51	T	90	Very high	84.8	Confident	1 Å²	1	26.9 Å²	26.9	1%	0.006	14%	0.138	C	C	.	.	H	α-helix	trans	-65.7	-37	175.3	-55.4	0	0	0	0	111.3	P47 L48 G49 S53 P55 F71 A74 R75 F144 N148	P47-T51 WeakPolarHBondContact O-CB 3.14Å; P47-T51 PolarHBondContact O-N 3.01Å; P47-T51 PolarHBondContact O-OG1 2.96Å; L48-T51 PolarHBondContact O-N 3.45Å; G49-T51 PolarHBondContact O-N 2.88Å; T51-S53 VanDerWaalsContact C-N 3.28Å; T51-S53 PolarHBondContact O-N 3.47Å; T51-P55 WeakPolarHBondContact O-CD 3.43Å; T51-F71 HydrophobicContact CG2-CE1 4.35Å; T51-F71 HydrophobicContact CG2-CZ 4.33Å; T51-A74 HydrophobicContact CG2-CB 4.39Å; T51-R75 HydrophobicContact CG2-CG 4.24Å; T51-F144 HydrophobicContact CG2-CD1 4.08Å; T51-N148 WeakPolarHBondContact CG2-ND2 3.37Å; T51-N148 PolarHBondContact OG1-ND2 3.33Å
52	A	88.1	Confident	83.3	Confident	10 Å²	10	35.1 Å²	35.1	8%	0.083	18%	0.176	C	C	.	.	H	α-helix	trans	-72.2	-20	179	0	0	0	0	0	113.5	L48 G49 L50 Y186 N190	L48-A52 WeakPolarHBondContact O-CB 3.21Å; L48-A52 PolarHBondContact O-N 2.91Å; G49-A52 CarbonylContact O-C 3.42Å; G49-A52 PolarHBondContact O-N 3.03Å; G49-A52 VanDerWaalsContact O-N 3.13Å; L50-A52 VanDerWaalsContact C-N 3.3Å; L50-A52 PolarHBondContact O-N 3.44Å; A52-Y186 HydrophobicContact CB-CE2 3.64Å; A52-Y186 VanDerWaalsContact CB-OH 3.32Å; A52-Y186 WeakPolarHBondContact CB-OH 3.46Å; A52-N190 VanDerWaalsContact CB-ND2 3.34Å; A52-N190 WeakPolarHBondContact CB-ND2 3.33Å; A52-N190 PolarHBondContact O-ND2 3.11Å
53	S	82.9	Confident	81.9	Confident	0 Å²	0	35 Å²	35	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-79.8	-27.6	176.7	70.7	0	0	0	0	112.8	G49 L50 T51 L56 V57 N190 F193	G49-S53 PolarHBondContact O-N 3.19Å; L50-S53 PolarHBondContact O-N 3.48Å; L50-S53 PolarHBondContact O-OG 3.31Å; T51-S53 VanDerWaalsContact C-N 3.28Å; T51-S53 PolarHBondContact O-N 3.47Å; S53-L56 WeakPolarHBondContact O-CB 3.34Å; S53-L56 PolarHBondContact O-N 3.43Å; S53-L56 VanDerWaalsContact O-N 3.09Å; S53-V57 WeakPolarHBondContact O-CG2 3.27Å; S53-V57 PolarHBondContact O-N 2.7Å; S53-V57 VanDerWaalsContact O-N 3.1Å; S53-N190 PolarHBondContact N-ND2 3.12Å; S53-F193 WeakPolarHBondContact OG-CD1 3.44Å
54	I	83.1	Confident	80.9	Confident	26 Å²	26	38.5 Å²	38.5	13%	0.133	20%	0.198	C	C	.	.	H	α-helix	trans	-56.8	-47.6	-177	-57.3	-53.6	0	0	0	113.7	L50 L56 V57 L58 F71 L140 F144	L50-I54 WeakPolarHBondContact O-CG1 3.42Å; I54-L56 PolarHBondContact O-N 3.31Å; I54-V57 PolarHBondContact O-N 3.05Å; I54-V57 VanDerWaalsContact O-N 3.11Å; I54-L58 HydrophobicContact CG2-CD1 3.79Å; I54-L58 HydrophobicContact CG2-CG 4.01Å; I54-L58 WeakPolarHBondContact O-CG 3.39Å; I54-L58 PolarHBondContact O-N 3.07Å; I54-F71 HydrophobicContact CB-CE1 3.77Å; I54-F71 HydrophobicContact CB-CE2 4.39Å; I54-F71 HydrophobicContact CB-CZ 3.58Å; I54-F71 HydrophobicContact CG1-CZ 3.97Å; I54-F71 HydrophobicContact CG2-CD1 4.48Å; I54-F71 HydrophobicContact CG2-CD2 4.45Å; I54-F71 HydrophobicContact CG2-CE1 3.89Å; I54-F71 HydrophobicContact CG2-CE2 3.84Å; I54-F71 HydrophobicContact CG2-CZ 3.52Å; I54-L140 HydrophobicContact CG2-CD2 4.18Å; I54-F144 HydrophobicContact CD1-CE1 4.12Å; I54-F144 HydrophobicContact CD1-CE2 4.2Å; I54-F144 HydrophobicContact CD1-CZ 3.58Å; I54-F144 HydrophobicContact CG1-CD1 4.28Å; I54-F144 HydrophobicContact CG1-CE1 3.61Å; I54-F144 HydrophobicContact CG1-CE2 4.01Å; I54-F144 HydrophobicContact CG1-CZ 3.47Å; I54-F144 VanDerWaalsContact CG1-CZ 3.47Å
55	P	79.7	Confident	80	Confident	24 Å²	24	46.7 Å²	46.7	16%	0.156	23%	0.23	C	C	.	.	H	α-helix	trans	-59.1	-34.9	177.6	-25.9	36.6	0	0	0	113.3	T51 L58 Q59 F71	T51-P55 WeakPolarHBondContact O-CD 3.43Å; P55-L58 PolarHBondContact O-N 3.33Å; P55-Q59 WeakPolarHBondContact O-CB 3.3Å; P55-Q59 PolarHBondContact O-N 2.93Å; P55-F71 HydrophobicContact CG-CD1 3.84Å; P55-F71 HydrophobicContact CG-CE1 3.93Å
56	L	73.2	Confident	79.1	Confident	78 Å²	78	55.3 Å²	55.3	41%	0.408	27%	0.268	S	S	.	.	H	α-helix	trans	-67.5	-41.1	177	-65.5	170.5	0	0	0	110.9	S53 I54 Q59 L194	S53-L56 WeakPolarHBondContact O-CB 3.34Å; S53-L56 PolarHBondContact O-N 3.43Å; S53-L56 VanDerWaalsContact O-N 3.09Å; I54-L56 PolarHBondContact O-N 3.31Å; L56-Q59 PolarHBondContact O-N 3.23Å; L56-L194 HydrophobicContact CB-CD1 4.31Å; L56-L194 HydrophobicContact CD1-CD1 3.51Å
57	V	71.6	Confident	78.3	Confident	34 Å²	34	58.8 Å²	58.8	21%	0.206	28%	0.284	C	S	.	.	H	α-helix	trans	-66.9	-38.8	174.6	-175.7	0	0	0	0	111.8	S53 I54 L125 L194	S53-V57 WeakPolarHBondContact O-CG2 3.27Å; S53-V57 PolarHBondContact O-N 2.7Å; S53-V57 VanDerWaalsContact O-N 3.1Å; I54-V57 PolarHBondContact O-N 3.05Å; I54-V57 VanDerWaalsContact O-N 3.11Å; V57-L125 HydrophobicContact CG1-CD2 3.48Å; V57-L125 VanDerWaalsContact CG1-CD2 3.48Å; V57-L194 HydrophobicContact CG2-CD2 3.68Å
58	L	69.3	Low	77.5	Confident	17 Å²	17	61 Å²	61	9%	0.089	29%	0.294	C	S	.	.	H	α-helix	trans	-69.6	-35.3	177.3	-68.5	177.5	0	0	0	112.8	I54 P55 N60 R61 V63 L140	I54-L58 HydrophobicContact CG2-CD1 3.79Å; I54-L58 HydrophobicContact CG2-CG 4.01Å; I54-L58 WeakPolarHBondContact O-CG 3.39Å; I54-L58 PolarHBondContact O-N 3.07Å; P55-L58 PolarHBondContact O-N 3.33Å; L58-N60 VanDerWaalsContact C-N 3.29Å; L58-N60 PolarHBondContact O-N 2.92Å; L58-R61 WeakPolarHBondContact O-CB 3.21Å; L58-R61 PolarHBondContact O-N 2.68Å; L58-V63 HydrophobicContact CB-CB 4.19Å; L58-V63 HydrophobicContact CB-CG1 4.42Å; L58-V63 HydrophobicContact CB-CG2 4.04Å; L58-V63 HydrophobicContact CD2-CG2 4.25Å; L58-V63 WeakPolarHBondContact O-CB 3.48Å; L58-V63 VanDerWaalsContact O-CG2 3.25Å; L58-V63 WeakPolarHBondContact O-CG2 3.11Å; L58-L140 HydrophobicContact CD1-CD2 4.22Å; L58-L140 HydrophobicContact CD2-CD2 4.46Å
59	Q	67.8	Low	76.9	Confident	96 Å²	96	62 Å²	62	45%	0.449	31%	0.307	S	S	.	.	H	α-helix	trans	-62.7	-37.1	179.2	-174.2	177.1	11.1	0	0	112	P55 L56 R61 H62	P55-Q59 WeakPolarHBondContact O-CB 3.3Å; P55-Q59 PolarHBondContact O-N 2.93Å; L56-Q59 PolarHBondContact O-N 3.23Å; Q59-R61 PolarHBondContact O-N 3.02Å; Q59-R61 VanDerWaalsContact O-N 3.12Å; Q59-H62 PolarHBondContact O-N 3.22Å; Q59-H62 VanDerWaalsContact O-N 3.16Å
60	N	63.7	Low	76.5	Confident	136 Å²	136	63.7 Å²	63.7	73%	0.727	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-14.2	174.6	-69.1	-20.9	0	0	0	113.3	L58	L58-N60 VanDerWaalsContact C-N 3.29Å; L58-N60 PolarHBondContact O-N 2.92Å
61	R	65.2	Low	76.3	Confident	69 Å²	69	63.5 Å²	63.5	26%	0.26	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102	17.9	177.7	-63	-172.7	173.7	-147.8	-14.9	113.7	L58 Q59 V63 L125 G126 H135	L58-R61 WeakPolarHBondContact O-CB 3.21Å; L58-R61 PolarHBondContact O-N 2.68Å; Q59-R61 PolarHBondContact O-N 3.02Å; Q59-R61 VanDerWaalsContact O-N 3.12Å; R61-V63 HydrophobicContact CB-CG2 4.23Å; R61-V63 PolarHBondContact O-N 2.68Å; R61-V63 VanDerWaalsContact O-N 3.12Å; R61-L125 VanDerWaalsContact NH2-C 3.35Å; R61-L125 PolarHBondContact NH2-O 3.26Å; R61-G126 PolarHBondContact NH1-O 3.36Å; R61-H135 PolarHBondContact NH1-NE2 3.26Å
62	H	66	Low	76.2	Confident	177 Å²	177	66 Å²	66	82%	0.819	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	57.6	25.8	-178.4	-56.2	-72.2	0	0	0	114.6	Q59 T64	Q59-H62 PolarHBondContact O-N 3.22Å; Q59-H62 VanDerWaalsContact O-N 3.16Å; H62-T64 PolarHBondContact O-N 3.16Å
63	V	69.1	Low	76.2	Confident	28 Å²	28	70.1 Å²	70.1	17%	0.17	35%	0.354	C	S	.	.			trans	-62.2	130.3	175.3	173.1	0	0	0	0	110.1	L58 R61 Q67 Q68	L58-V63 HydrophobicContact CB-CB 4.19Å; L58-V63 HydrophobicContact CB-CG1 4.42Å; L58-V63 HydrophobicContact CB-CG2 4.04Å; L58-V63 HydrophobicContact CD2-CG2 4.25Å; L58-V63 WeakPolarHBondContact O-CB 3.48Å; L58-V63 VanDerWaalsContact O-CG2 3.25Å; L58-V63 WeakPolarHBondContact O-CG2 3.11Å; R61-V63 HydrophobicContact CB-CG2 4.23Å; R61-V63 PolarHBondContact O-N 2.68Å; R61-V63 VanDerWaalsContact O-N 3.12Å; V63-Q67 HydrophobicContact CG1-CB 3.39Å; V63-Q67 HydrophobicContact CG1-CG 4.27Å; V63-Q68 HydrophobicContact CG1-CG 4.4Å; V63-Q68 PolarHBondContact O-NE2 3Å
64	T	76.3	Confident	76.6	Confident	74 Å²	74	70.1 Å²	70.1	45%	0.454	35%	0.354	S	S	.	.			trans	-63.8	153.2	-175	64.6	0	0	0	0	112.3	H62 K66 Q67 Q68	H62-T64 PolarHBondContact O-N 3.16Å; T64-K66 PolarHBondContact O-N 3.26Å; T64-Q67 WeakPolarHBondContact O-CB 3.29Å; T64-Q67 PolarHBondContact O-N 2.83Å; T64-Q67 VanDerWaalsContact OG1-CG 3.27Å; T64-Q67 WeakPolarHBondContact OG1-CG 3.39Å; T64-Q67 PolarHBondContact OG1-N 3.16Å; T64-Q67 PolarHBondContact OG1-OE1 3.36Å; T64-Q68 PolarHBondContact O-N 2.74Å
65	Y	74.6	Confident	76.9	Confident	172 Å²	172	74.6 Å²	74.6	68%	0.675	37%	0.37	S	S	*	.	H	α-helix	trans	-56.9	-33	173.9	-71.3	-68.4	0	0	0	113.1	Q67 Q68 A69	Y65-Q67 VanDerWaalsContact C-N 3.29Å; Y65-Q67 PolarHBondContact O-N 3.12Å; Y65-Q68 PolarHBondContact O-N 2.87Å; Y65-A69 WeakPolarHBondContact O-CB 3.44Å; Y65-A69 PolarHBondContact O-N 3.49Å
66	K	77.1	Confident	77.4	Confident	181 Å²	181	79.3 Å²	79.3	79%	0.787	38%	0.384	S	S	*	.	H	α-helix	trans	-60.7	-40.2	174.9	-173.5	178.1	-179.6	-179.4	0	111.5	T64 A70	T64-K66 PolarHBondContact O-N 3.26Å; K66-A70 PolarHBondContact O-N 3.22Å; K66-A70 VanDerWaalsContact O-N 3.09Å
67	Q	78.6	Confident	78.3	Confident	72 Å²	72	75.6 Å²	75.6	34%	0.336	37%	0.365	S	S	.	.	H	α-helix	trans	-72	-38.9	177.2	-69.8	169.7	-56.1	0	0	111.6	V63 T64 Y65 A69 A70 F71 L137	V63-Q67 HydrophobicContact CG1-CB 3.39Å; V63-Q67 HydrophobicContact CG1-CG 4.27Å; T64-Q67 WeakPolarHBondContact O-CB 3.29Å; T64-Q67 PolarHBondContact O-N 2.83Å; T64-Q67 VanDerWaalsContact OG1-CG 3.27Å; T64-Q67 WeakPolarHBondContact OG1-CG 3.39Å; T64-Q67 PolarHBondContact OG1-N 3.16Å; T64-Q67 PolarHBondContact OG1-OE1 3.36Å; Y65-Q67 VanDerWaalsContact C-N 3.29Å; Y65-Q67 PolarHBondContact O-N 3.12Å; Q67-A69 VanDerWaalsContact C-N 3.32Å; Q67-A69 PolarHBondContact O-N 2.83Å; Q67-A70 PolarHBondContact O-N 3.35Å; Q67-F71 PolarHBondContact O-N 3.39Å; Q67-L137 HydrophobicContact CB-CD2 3.39Å; Q67-L137 HydrophobicContact CG-CD2 3.59Å; Q67-L137 WeakPolarHBondContact O-CD2 3.26Å
68	Q	76.1	Confident	79.2	Confident	46 Å²	46	75.7 Å²	75.7	22%	0.215	36%	0.363	C	S	.	.	H	α-helix	trans	-62.9	-39.3	173.4	-64.6	-177.9	40.3	0	0	112.1	V63 T64 Y65 F71 S72	V63-Q68 HydrophobicContact CG1-CG 4.4Å; V63-Q68 PolarHBondContact O-NE2 3Å; T64-Q68 PolarHBondContact O-N 2.74Å; Y65-Q68 PolarHBondContact O-N 2.87Å; Q68-F71 PolarHBondContact O-N 3.2Å; Q68-S72 PolarHBondContact O-N 2.9Å
69	A	80	Confident	80.1	Confident	54 Å²	54	79 Å²	79	45%	0.446	39%	0.387	S	S	.	.	H	α-helix	trans	-61.8	-42.7	173.8	0	0	0	0	0	111.6	Y65 Q67 F71 S72	Y65-A69 WeakPolarHBondContact O-CB 3.44Å; Y65-A69 PolarHBondContact O-N 3.49Å; Q67-A69 VanDerWaalsContact C-N 3.32Å; Q67-A69 PolarHBondContact O-N 2.83Å; A69-F71 VanDerWaalsContact C-N 3.34Å; A69-F71 PolarHBondContact O-N 2.83Å; A69-S72 WeakPolarHBondContact O-CB 3.48Å; A69-S72 PolarHBondContact O-N 3.28Å; A69-S72 PolarHBondContact O-OG 3.42Å
70	A	84	Confident	81.3	Confident	37 Å²	37	77.4 Å²	77.4	31%	0.306	38%	0.381	S	S	.	.	H	α-helix	trans	-62.6	-38.8	174.3	0	0	0	0	0	112.4	K66 Q67 S72 F73 L137 T141	K66-A70 PolarHBondContact O-N 3.22Å; K66-A70 VanDerWaalsContact O-N 3.09Å; Q67-A70 PolarHBondContact O-N 3.35Å; A70-S72 VanDerWaalsContact C-N 3.31Å; A70-S72 PolarHBondContact O-N 2.96Å; A70-F73 VanDerWaalsContact O-CD2 3.32Å; A70-F73 WeakPolarHBondContact O-CD2 3.45Å; A70-L137 HydrophobicContact CB-CD2 3.82Å; A70-L137 HydrophobicContact CB-CG 4.49Å; A70-T141 VanDerWaalsContact O-CG2 3.25Å; A70-T141 WeakPolarHBondContact O-CG2 3.5Å
71	F	86.4	Confident	82.8	Confident	1 Å²	1	71.4 Å²	71.4	0%	0.004	35%	0.349	C	S	.	.	H	α-helix	trans	-69	-27.3	174.9	-173.8	-97.9	0	0	0	113.3	T51 I54 P55 Q67 Q68 A69 F73 A74 L137 L140 F144	T51-F71 HydrophobicContact CG2-CE1 4.35Å; T51-F71 HydrophobicContact CG2-CZ 4.33Å; I54-F71 HydrophobicContact CB-CE1 3.77Å; I54-F71 HydrophobicContact CB-CE2 4.39Å; I54-F71 HydrophobicContact CB-CZ 3.58Å; I54-F71 HydrophobicContact CG1-CZ 3.97Å; I54-F71 HydrophobicContact CG2-CD1 4.48Å; I54-F71 HydrophobicContact CG2-CD2 4.45Å; I54-F71 HydrophobicContact CG2-CE1 3.89Å; I54-F71 HydrophobicContact CG2-CE2 3.84Å; I54-F71 HydrophobicContact CG2-CZ 3.52Å; P55-F71 HydrophobicContact CG-CD1 3.84Å; P55-F71 HydrophobicContact CG-CE1 3.93Å; Q67-F71 PolarHBondContact O-N 3.39Å; Q68-F71 PolarHBondContact O-N 3.2Å; A69-F71 VanDerWaalsContact C-N 3.34Å; A69-F71 PolarHBondContact O-N 2.83Å; F71-F73 PolarHBondContact O-N 3.18Å; F71-A74 HydrophobicContact CE1-CB 4.48Å; F71-A74 HydrophobicContact CE2-CB 4.29Å; F71-A74 HydrophobicContact CZ-CB 4.24Å; F71-A74 WeakPolarHBondContact O-CB 3.35Å; F71-A74 PolarHBondContact O-N 3.07Å; F71-L137 HydrophobicContact CB-CD1 4.29Å; F71-L140 HydrophobicContact CD2-CD2 4.26Å; F71-L140 HydrophobicContact CD2-CG 4.27Å; F71-L140 HydrophobicContact CE2-CD2 4.25Å; F71-L140 HydrophobicContact CE2-CG 4.02Å; F71-F144 HydrophobicContact CE2-CB 3.85Å; F71-F144 AromaticContact CE2-CD2 3.91Å; F71-F144 HydrophobicContact CE2-CD2 3.91Å; F71-F144 AromaticContact CE2-CG 3.9Å; F71-F144 HydrophobicContact CE2-CG 3.9Å; F71-F144 HydrophobicContact CZ-CB 3.94Å; F71-F144 HydrophobicContact CZ-CD1 4.19Å; F71-F144 HydrophobicContact CZ-CD2 4.16Å; F71-F144 AromaticContact CZ-CG 3.82Å; F71-F144 HydrophobicContact CZ-CG 3.82Å
72	S	86.6	Confident	84.2	Confident	54 Å²	54	69.8 Å²	69.8	38%	0.378	35%	0.345	S	S	.	.	H	α-helix	trans	-57.7	-24.6	179.4	79.6	0	0	0	0	113.7	Q68 A69 A70 A74 R75	Q68-S72 PolarHBondContact O-N 2.9Å; A69-S72 WeakPolarHBondContact O-CB 3.48Å; A69-S72 PolarHBondContact O-N 3.28Å; A69-S72 PolarHBondContact O-OG 3.42Å; A70-S72 VanDerWaalsContact C-N 3.31Å; A70-S72 PolarHBondContact O-N 2.96Å; S72-A74 PolarHBondContact O-N 2.77Å; S72-R75 PolarHBondContact O-N 3.3Å; S72-R75 VanDerWaalsContact O-N 3.12Å
73	F	88.9	Confident	85.5	Confident	96 Å²	96	66.7 Å²	66.7	42%	0.421	33%	0.334	S	S	.	.	G	3₁₀ helix	trans	-58.3	-26.5	172.4	-75.3	-84.6	0	0	0	113	A70 F71 R75 W76 T141 F145	A70-F73 VanDerWaalsContact O-CD2 3.32Å; A70-F73 WeakPolarHBondContact O-CD2 3.45Å; F71-F73 PolarHBondContact O-N 3.18Å; F73-R75 PolarHBondContact O-N 2.99Å; F73-R75 VanDerWaalsContact O-N 3.1Å; F73-W76 AromaticContact CD1-CD2 3.73Å; F73-W76 HydrophobicContact CD1-CD2 3.73Å; F73-W76 AromaticContact CD1-CE2 3.5Å; F73-W76 HydrophobicContact CD1-CE3 4.06Å; F73-W76 HydrophobicContact CD1-CG 4.31Å; F73-W76 HydrophobicContact CD1-CH2 4.05Å; F73-W76 AromaticContact CD1-CZ2 3.69Å; F73-W76 HydrophobicContact CD1-CZ2 3.69Å; F73-W76 HydrophobicContact CD1-CZ3 4.22Å; F73-W76 AromaticContact CD1-NE1 3.88Å; F73-W76 HydrophobicContact CE1-CD2 4.22Å; F73-W76 AromaticContact CE1-CE2 3.69Å; F73-W76 HydrophobicContact CE1-CE3 4.34Å; F73-W76 AromaticContact CE1-CH2 3.53Å; F73-W76 HydrophobicContact CE1-CH2 3.53Å; F73-W76 AromaticContact CE1-CZ2 3.33Å; F73-W76 HydrophobicContact CE1-CZ2 3.33Å; F73-W76 HydrophobicContact CE1-CZ3 4.03Å; F73-W76 HydrophobicContact CZ-CZ2 4.2Å; F73-W76 VanDerWaalsContact O-CB 3.27Å; F73-W76 WeakPolarHBondContact O-CB 3.35Å; F73-W76 PolarHBondContact O-N 3.35Å; F73-T141 HydrophobicContact CB-CG2 4.09Å; F73-F145 WeakPolarHBondContact O-CD2 3.4Å
74	A	90.7	Very high	86.7	Confident	0 Å²	0	67.1 Å²	67.1	0%	0	33%	0.332	C	S	.	.	G	3₁₀ helix	trans	-58.4	-24.8	176.2	0	0	0	0	0	113.4	T51 F71 S72 P77 F144 N148	T51-A74 HydrophobicContact CG2-CB 4.39Å; F71-A74 HydrophobicContact CE1-CB 4.48Å; F71-A74 HydrophobicContact CE2-CB 4.29Å; F71-A74 HydrophobicContact CZ-CB 4.24Å; F71-A74 WeakPolarHBondContact O-CB 3.35Å; F71-A74 PolarHBondContact O-N 3.07Å; S72-A74 PolarHBondContact O-N 2.77Å; A74-P77 WeakPolarHBondContact O-CD 3.23Å; A74-F144 HydrophobicContact CB-CB 3.73Å; A74-N148 WeakPolarHBondContact O-CB 3.48Å; A74-N148 VanDerWaalsContact O-CG 3.27Å; A74-N148 PolarHBondContact O-ND2 3.05Å
75	R	89.4	Confident	87.6	Confident	121 Å²	121	63.6 Å²	63.6	46%	0.457	31%	0.311	S	S	.	.	G	3₁₀ helix	trans	-87.1	-10.8	179.1	-59.9	-178.3	-171.6	171.4	1.3	113.8	T51 S72 F73 P77 F78	T51-R75 HydrophobicContact CG2-CG 4.24Å; S72-R75 PolarHBondContact O-N 3.3Å; S72-R75 VanDerWaalsContact O-N 3.12Å; F73-R75 PolarHBondContact O-N 2.99Å; F73-R75 VanDerWaalsContact O-N 3.1Å; R75-P77 VanDerWaalsContact C-N 3.34Å; R75-F78 PolarHBondContact O-N 2.7Å
76	W	89.8	Confident	88.5	Confident	122 Å²	122	55.4 Å²	55.4	46%	0.462	28%	0.279	S	S	.	.	H	α-helix	trans	-57.9	-33.7	-176.5	-80.1	32.5	0	0	0	115.2	F73 F78 S79 L80 F145	F73-W76 AromaticContact CD1-CD2 3.73Å; F73-W76 HydrophobicContact CD1-CD2 3.73Å; F73-W76 AromaticContact CD1-CE2 3.5Å; F73-W76 HydrophobicContact CD1-CE3 4.06Å; F73-W76 HydrophobicContact CD1-CG 4.31Å; F73-W76 HydrophobicContact CD1-CH2 4.05Å; F73-W76 AromaticContact CD1-CZ2 3.69Å; F73-W76 HydrophobicContact CD1-CZ2 3.69Å; F73-W76 HydrophobicContact CD1-CZ3 4.22Å; F73-W76 AromaticContact CD1-NE1 3.88Å; F73-W76 HydrophobicContact CE1-CD2 4.22Å; F73-W76 AromaticContact CE1-CE2 3.69Å; F73-W76 HydrophobicContact CE1-CE3 4.34Å; F73-W76 AromaticContact CE1-CH2 3.53Å; F73-W76 HydrophobicContact CE1-CH2 3.53Å; F73-W76 AromaticContact CE1-CZ2 3.33Å; F73-W76 HydrophobicContact CE1-CZ2 3.33Å; F73-W76 HydrophobicContact CE1-CZ3 4.03Å; F73-W76 HydrophobicContact CZ-CZ2 4.2Å; F73-W76 VanDerWaalsContact O-CB 3.27Å; F73-W76 WeakPolarHBondContact O-CB 3.35Å; F73-W76 PolarHBondContact O-N 3.35Å; W76-F78 PolarHBondContact O-N 2.89Å; W76-F78 VanDerWaalsContact O-N 3.16Å; W76-S79 CarbonylContact O-C 3.58Å; W76-S79 WeakPolarHBondContact O-CA 3.05Å; W76-S79 WeakPolarHBondContact O-CB 3.34Å; W76-S79 PolarHBondContact O-N 3.41Å; W76-L80 HydrophobicContact CB-CD1 4.29Å; W76-L80 HydrophobicContact CE3-CD1 4.09Å; W76-L80 WeakPolarHBondContact O-CG 3.37Å; W76-L80 PolarHBondContact O-N 3.27Å; W76-F145 HydrophobicContact CB-CE2 4.38Å
77	P	93.5	Very high	89.3	Confident	0 Å²	0	48.7 Å²	48.7	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-54.5	-37.4	179.3	-28.4	35.7	0	0	0	113.8	A74 R75 S79 L80 K81 W84 F145 N148 F149 A152	A74-P77 WeakPolarHBondContact O-CD 3.23Å; R75-P77 VanDerWaalsContact C-N 3.34Å; P77-S79 PolarHBondContact O-N 3.09Å; P77-L80 PolarHBondContact O-N 2.98Å; P77-L80 VanDerWaalsContact O-N 3.16Å; P77-K81 PolarHBondContact O-N 3.3Å; P77-W84 HydrophobicContact CB-CH2 3.96Å; P77-W84 HydrophobicContact CB-CZ2 4.49Å; P77-W84 WeakPolarHBondContact O-CH2 3.27Å; P77-F145 HydrophobicContact CG-CD1 4.43Å; P77-F145 HydrophobicContact CG-CD2 3.82Å; P77-F145 HydrophobicContact CG-CE1 4.32Å; P77-F145 HydrophobicContact CG-CE2 3.71Å; P77-F145 HydrophobicContact CG-CG 4.19Å; P77-F145 HydrophobicContact CG-CZ 3.97Å; P77-N148 HydrophobicContact CB-CB 4.33Å; P77-N148 HydrophobicContact CG-CB 4.06Å; P77-F149 HydrophobicContact CB-CB 4.02Å; P77-F149 HydrophobicContact CB-CD2 4.43Å; P77-F149 HydrophobicContact CG-CB 4.07Å; P77-A152 HydrophobicContact CB-CB 4.26Å
78	F	90.3	Very high	90	Very high	37 Å²	37	45.4 Å²	45.4	16%	0.162	24%	0.238	C	C	.	.	H	α-helix	trans	-65.5	-24	175.1	-85.5	-87.7	0	0	0	114	L48 R75 W76 K81 N148 A151 A152 D155	L48-F78 HydrophobicContact CD1-CE1 3.92Å; L48-F78 HydrophobicContact CD1-CE2 4.45Å; L48-F78 HydrophobicContact CD1-CZ 3.78Å; L48-F78 HydrophobicContact CD2-CD1 4.24Å; L48-F78 HydrophobicContact CD2-CD2 3.56Å; L48-F78 HydrophobicContact CD2-CE1 3.94Å; L48-F78 HydrophobicContact CD2-CE2 3.21Å; L48-F78 HydrophobicContact CD2-CG 4.06Å; L48-F78 HydrophobicContact CD2-CZ 3.42Å; L48-F78 VanDerWaalsContact CD2-CZ 3.42Å; L48-F78 HydrophobicContact CG-CE1 4.21Å; L48-F78 HydrophobicContact CG-CE2 3.84Å; L48-F78 HydrophobicContact CG-CZ 3.6Å; R75-F78 PolarHBondContact O-N 2.7Å; W76-F78 PolarHBondContact O-N 2.89Å; W76-F78 VanDerWaalsContact O-N 3.16Å; F78-K81 WeakPolarHBondContact O-CG 3.41Å; F78-N148 HydrophobicContact CD2-CB 4.28Å; F78-N148 HydrophobicContact CE2-CB 4.3Å; F78-A151 HydrophobicContact CE2-CB 3.8Å; F78-A151 HydrophobicContact CZ-CB 3.72Å; F78-A152 HydrophobicContact CD1-CB 4.14Å; F78-A152 HydrophobicContact CD2-CB 3.98Å; F78-A152 HydrophobicContact CE1-CB 4.2Å; F78-A152 HydrophobicContact CE2-CB 4.04Å; F78-A152 HydrophobicContact CG-CB 4.04Å; F78-A152 HydrophobicContact CZ-CB 4.15Å; F78-D155 HydrophobicContact CE1-CB 4.13Å
79	S	88.9	Confident	90.6	Very high	85 Å²	85	43.2 Å²	43.2	59%	0.594	23%	0.227	S	C	*	.	H	α-helix	trans	-86	-30	174.2	-57.6	0	0	0	0	112.1	W76 P77	W76-S79 CarbonylContact O-C 3.58Å; W76-S79 WeakPolarHBondContact O-CA 3.05Å; W76-S79 WeakPolarHBondContact O-CB 3.34Å; W76-S79 PolarHBondContact O-N 3.41Å; P77-S79 PolarHBondContact O-N 3.09Å
80	L	92.5	Very high	91.1	Very high	63 Å²	63	40.7 Å²	40.7	33%	0.33	21%	0.207	S	C	.	.	H	α-helix	trans	-94.3	-4.3	-175.5	-64.2	179.9	0	0	0	113.7	W76 P77 L82 L83 W84	W76-L80 HydrophobicContact CB-CD1 4.29Å; W76-L80 HydrophobicContact CE3-CD1 4.09Å; W76-L80 WeakPolarHBondContact O-CG 3.37Å; W76-L80 PolarHBondContact O-N 3.27Å; P77-L80 PolarHBondContact O-N 2.98Å; P77-L80 VanDerWaalsContact O-N 3.16Å; L80-L82 PolarHBondContact O-N 3.06Å; L80-L83 HydrophobicContact CB-CD1 4.14Å; L80-L83 HydrophobicContact CD2-CD1 4.14Å; L80-L83 VanDerWaalsContact O-CB 3.23Å; L80-L83 WeakPolarHBondContact O-CB 3.44Å; L80-L83 VanDerWaalsContact O-CG 3.3Å; L80-L83 WeakPolarHBondContact O-CG 3.41Å; L80-L83 PolarHBondContact O-N 3.44Å; L80-W84 HydrophobicContact CB-CH2 4.32Å; L80-W84 HydrophobicContact CB-CZ3 3.78Å; L80-W84 WeakPolarHBondContact O-CZ3 3.4Å
81	K	94.9	Very high	91.4	Very high	10 Å²	10	42.2 Å²	42.2	4%	0.043	21%	0.212	C	C	.	.	G	3₁₀ helix	trans	-54.4	-26	-173.2	61.6	159.8	178.5	166.8	0	115.1	P77 F78 L83 W84 A85 A152 D155 I156 D159 T418	P77-K81 PolarHBondContact O-N 3.3Å; F78-K81 WeakPolarHBondContact O-CG 3.41Å; K81-L83 PolarHBondContact O-N 3.08Å; K81-W84 VanDerWaalsContact CA-CH2 3.42Å; K81-W84 HydrophobicContact CB-CH2 3.99Å; K81-W84 HydrophobicContact CB-CZ2 3.74Å; K81-W84 PolarHBondContact O-N 3.07Å; K81-A85 WeakPolarHBondContact O-CB 3.44Å; K81-A85 PolarHBondContact O-N 3.47Å; K81-A152 HydrophobicContact CB-CB 4.33Å; K81-D155 IonicContact NZ-OD2 3.93Å; K81-D155 PolarHBondContact NZ-OD2 2.86Å; K81-I156 HydrophobicContact CB-CD1 3.83Å; K81-I156 HydrophobicContact CB-CG1 4.2Å; K81-I156 HydrophobicContact CD-CG1 3.96Å; K81-D159 IonicContact NZ-OD2 4Å; K81-T418 HydrophobicContact CB-CG2 4.4Å; K81-T418 HydrophobicContact CD-CG2 3.75Å; K81-T418 HydrophobicContact CG-CG2 3.59Å
82	L	93.6	Very high	91.5	Very high	36 Å²	36	43.6 Å²	43.6	19%	0.188	22%	0.218	C	C	.	.	G	3₁₀ helix	trans	-57.3	-29	172.4	-176.7	59.3	0	0	0	112.7	L80 W84 P86 L268 T418 L419	L80-L82 PolarHBondContact O-N 3.06Å; L82-W84 PolarHBondContact O-N 3.4Å; L82-P86 VanDerWaalsContact O-CD 3.27Å; L82-P86 WeakPolarHBondContact O-CD 3.45Å; L82-L268 HydrophobicContact CD1-CD1 4.06Å; L82-L268 HydrophobicContact CD1-CD2 4.05Å; L82-T418 HydrophobicContact CB-CG2 3.9Å; L82-T418 HydrophobicContact CD1-CG2 4.19Å; L82-L419 HydrophobicContact CD1-CB 3.91Å; L82-L419 HydrophobicContact CD1-CD1 4.33Å; L82-L419 HydrophobicContact CD2-CD1 3.9Å
83	L	94.4	Very high	91.4	Very high	111 Å²	111	43.4 Å²	43.4	58%	0.581	22%	0.217	S	C	*	.	G	3₁₀ helix	trans	-64.9	-35.7	-179.2	-63.8	-179.2	0	0	0	112.7	L80 K81 Y265	L80-L83 HydrophobicContact CB-CD1 4.14Å; L80-L83 HydrophobicContact CD2-CD1 4.14Å; L80-L83 VanDerWaalsContact O-CB 3.23Å; L80-L83 WeakPolarHBondContact O-CB 3.44Å; L80-L83 VanDerWaalsContact O-CG 3.3Å; L80-L83 WeakPolarHBondContact O-CG 3.41Å; L80-L83 PolarHBondContact O-N 3.44Å; K81-L83 PolarHBondContact O-N 3.08Å; L83-Y265 PolarHBondContact O-OH 2.76Å
84	W	95.1	Very high	91	Very high	37 Å²	37	41.5 Å²	41.5	14%	0.14	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.5	-4.2	-179.4	67.6	95.8	0	0	0	114.3	P77 L80 K81 L82 P86 V87 V88 F149 A152 T153	P77-W84 HydrophobicContact CB-CH2 3.96Å; P77-W84 HydrophobicContact CB-CZ2 4.49Å; P77-W84 WeakPolarHBondContact O-CH2 3.27Å; L80-W84 HydrophobicContact CB-CH2 4.32Å; L80-W84 HydrophobicContact CB-CZ3 3.78Å; L80-W84 WeakPolarHBondContact O-CZ3 3.4Å; K81-W84 VanDerWaalsContact CA-CH2 3.42Å; K81-W84 HydrophobicContact CB-CH2 3.99Å; K81-W84 HydrophobicContact CB-CZ2 3.74Å; K81-W84 PolarHBondContact O-N 3.07Å; L82-W84 PolarHBondContact O-N 3.4Å; W84-P86 VanDerWaalsContact C-CD 3.44Å; W84-P86 VanDerWaalsContact C-N 3.26Å; W84-V87 WeakPolarHBondContact O-CA 3.49Å; W84-V87 VanDerWaalsContact O-CB 3.3Å; W84-V87 WeakPolarHBondContact O-CB 3.39Å; W84-V87 PolarHBondContact O-N 2.89Å; W84-V88 PolarHBondContact O-N 3.35Å; W84-F149 AromaticContact CD2-CE2 3.68Å; W84-F149 HydrophobicContact CD2-CE2 3.68Å; W84-F149 HydrophobicContact CD2-CZ 4.33Å; W84-F149 AromaticContact CE2-CE2 3.49Å; W84-F149 VanDerWaalsContact CE2-CE2 3.49Å; W84-F149 AromaticContact CE3-CE2 3.93Å; W84-F149 HydrophobicContact CE3-CE2 3.93Å; W84-F149 HydrophobicContact CG-CE2 4.24Å; W84-F149 HydrophobicContact CG-CZ 4.46Å; W84-F149 AromaticContact CH2-CD2 3.69Å; W84-F149 HydrophobicContact CH2-CD2 3.69Å; W84-F149 AromaticContact CH2-CE2 3.82Å; W84-F149 HydrophobicContact CH2-CE2 3.82Å; W84-F149 AromaticContact CZ2-CD2 3.6Å; W84-F149 HydrophobicContact CZ2-CD2 3.6Å; W84-F149 AromaticContact CZ2-CE2 3.59Å; W84-F149 HydrophobicContact CZ2-CE2 3.59Å; W84-F149 HydrophobicContact CZ3-CD2 4.21Å; W84-F149 AromaticContact CZ3-CE2 3.99Å; W84-F149 HydrophobicContact CZ3-CE2 3.99Å; W84-F149 AromaticContact NE1-CE2 3.93Å; W84-A152 HydrophobicContact CZ2-CB 3.98Å; W84-T153 PolarHBondContact NE1-OG1 3.07Å
85	A	94.6	Very high	90.5	Very high	0 Å²	0	52.5 Å²	52.5	0%	0	25%	0.251	C	S	.	.	H	α-helix	trans	-51	-40	171.8	0	0	0	0	0	113.3	K81 V87 V88 D89 I156 T415 T418	K81-A85 WeakPolarHBondContact O-CB 3.44Å; K81-A85 PolarHBondContact O-N 3.47Å; A85-V87 VanDerWaalsContact C-N 3.29Å; A85-V87 PolarHBondContact O-N 3.4Å; A85-V88 WeakPolarHBondContact O-CB 3.5Å; A85-V88 PolarHBondContact O-N 3.02Å; A85-D89 PolarHBondContact O-N 2.93Å; A85-I156 HydrophobicContact CB-CD1 3.89Å; A85-I156 HydrophobicContact CB-CG1 4.18Å; A85-I156 HydrophobicContact CB-CG2 3.97Å; A85-T415 VanDerWaalsContact C-OG1 3.29Å; A85-T415 PolarHBondContact O-OG1 2.84Å; A85-T418 HydrophobicContact CB-CG2 4.25Å
86	P	93.1	Very high	90.1	Very high	0 Å²	0	52.3 Å²	52.3	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-61.8	-32.6	172.9	-27.4	37.5	0	0	0	114.5	L82 W84 S90 T264 Y265 L268 T415	L82-P86 VanDerWaalsContact O-CD 3.27Å; L82-P86 WeakPolarHBondContact O-CD 3.45Å; W84-P86 VanDerWaalsContact C-CD 3.44Å; W84-P86 VanDerWaalsContact C-N 3.26Å; P86-S90 WeakPolarHBondContact O-CB 3.43Å; P86-S90 PolarHBondContact O-N 3.25Å; P86-S90 PolarHBondContact O-OG 3.34Å; P86-T264 HydrophobicContact CB-CG2 3.73Å; P86-Y265 HydrophobicContact CB-CD1 4.1Å; P86-Y265 HydrophobicContact CB-CD2 4.01Å; P86-Y265 HydrophobicContact CB-CE1 3.99Å; P86-Y265 HydrophobicContact CB-CE2 3.91Å; P86-Y265 HydrophobicContact CB-CG 4.1Å; P86-Y265 HydrophobicContact CG-CD1 3.85Å; P86-Y265 HydrophobicContact CG-CE1 3.66Å; P86-Y265 HydrophobicContact CG-CE2 4.49Å; P86-Y265 HydrophobicContact CG-CG 4.34Å; P86-L268 HydrophobicContact CG-CD2 3.96Å; P86-T415 WeakPolarHBondContact CA-OG1 3.45Å; P86-T415 HydrophobicContact CG-CG2 3.85Å
87	V	94.1	Very high	89.9	Confident	41 Å²	41	46.5 Å²	46.5	25%	0.248	23%	0.232	C	C	.	.	H	α-helix	trans	-69.5	-44.3	176	-177.8	0	0	0	0	109.7	W84 A85 D89 S90 V91 V261 Y265	W84-V87 WeakPolarHBondContact O-CA 3.49Å; W84-V87 VanDerWaalsContact O-CB 3.3Å; W84-V87 WeakPolarHBondContact O-CB 3.39Å; W84-V87 PolarHBondContact O-N 2.89Å; A85-V87 VanDerWaalsContact C-N 3.29Å; A85-V87 PolarHBondContact O-N 3.4Å; V87-D89 VanDerWaalsContact C-N 3.29Å; V87-D89 PolarHBondContact O-N 3.29Å; V87-S90 PolarHBondContact O-N 2.9Å; V87-S90 VanDerWaalsContact O-N 3.16Å; V87-S90 PolarHBondContact O-OG 3.02Å; V87-V91 HydrophobicContact CG1-CB 4.46Å; V87-V91 HydrophobicContact CG1-CG2 3.94Å; V87-V91 WeakPolarHBondContact O-CB 3.44Å; V87-V91 PolarHBondContact O-N 2.89Å; V87-V261 HydrophobicContact CG2-CG1 4.08Å; V87-Y265 HydrophobicContact CG2-CE2 4.32Å
88	V	93	Very high	89.6	Confident	2 Å²	2	47 Å²	47	1%	0.012	23%	0.234	C	C	.	.	H	α-helix	trans	-59.8	-39.8	176.9	175.5	0	0	0	0	111.5	W84 A85 W102 T153 I156 V157	W84-V88 PolarHBondContact O-N 3.35Å; A85-V88 WeakPolarHBondContact O-CB 3.5Å; A85-V88 PolarHBondContact O-N 3.02Å; V88-W102 HydrophobicContact CG1-CB 4.34Å; V88-W102 HydrophobicContact CG1-CD2 4.32Å; V88-W102 HydrophobicContact CG1-CG 3.93Å; V88-W102 HydrophobicContact CG2-CD2 4.34Å; V88-W102 PolarHBondContact O-NE1 3.48Å; V88-T153 HydrophobicContact CG2-CG2 4.08Å; V88-I156 HydrophobicContact CB-CG2 4.23Å; V88-I156 HydrophobicContact CG1-CG2 3.98Å; V88-I156 HydrophobicContact CG2-CD1 4.49Å; V88-V157 HydrophobicContact CG1-CG2 3.57Å
89	D	89.4	Confident	89.6	Confident	0 Å²	0	45.4 Å²	45.4	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-74.4	-22.2	178.5	-82.6	-36.2	0	0	0	114.2	A85 V87 R99 T264 G414 T415	A85-D89 PolarHBondContact O-N 2.93Å; V87-D89 VanDerWaalsContact C-N 3.29Å; V87-D89 PolarHBondContact O-N 3.29Å; D89-R99 IonicContact OD1-CZ 3.99Å; D89-R99 IonicContact OD1-NH1 3.74Å; D89-R99 PolarHBondContact OD1-NH1 3.22Å; D89-R99 IonicContact OD1-NH2 3.32Å; D89-T264 HydrophobicContact CB-CG2 4.27Å; D89-G414 PolarHBondContact OD2-N 2.54Å; D89-T415 WeakPolarHBondContact OD2-CB 3.16Å; D89-T415 PolarHBondContact OD2-N 3.46Å; D89-T415 PolarHBondContact OD2-OG1 2.71Å
90	S	89.8	Confident	89.8	Confident	2 Å²	2	42.8 Å²	42.8	1%	0.014	21%	0.205	C	C	.	.	H	α-helix	trans	-105.3	-32.8	-173.1	52.6	0	0	0	0	115.4	P86 V87 F92 M258 R259 V261 T264	P86-S90 WeakPolarHBondContact O-CB 3.43Å; P86-S90 PolarHBondContact O-N 3.25Å; P86-S90 PolarHBondContact O-OG 3.34Å; V87-S90 PolarHBondContact O-N 2.9Å; V87-S90 VanDerWaalsContact O-N 3.16Å; V87-S90 PolarHBondContact O-OG 3.02Å; S90-F92 WeakPolarHBondContact O-CD1 3.41Å; S90-M258 VanDerWaalsContact CA-O 3.29Å; S90-M258 WeakPolarHBondContact CA-O 3.46Å; S90-M258 WeakPolarHBondContact CB-O 3.49Å; S90-R259 WeakPolarHBondContact O-CA 3.42Å; S90-V261 WeakPolarHBondContact OG-CA 3.34Å; S90-V261 WeakPolarHBondContact OG-CG2 3.2Å; S90-T264 WeakPolarHBondContact CB-OG1 3.16Å
91	V	90.8	Very high	89.8	Confident	69 Å²	69	40.9 Å²	40.9	42%	0.418	20%	0.197	S	C	.	.	S	Bend	trans	-97.2	104.3	-177.3	179.2	0	0	0	0	108.4	V87 W102 V261	V87-V91 HydrophobicContact CG1-CB 4.46Å; V87-V91 HydrophobicContact CG1-CG2 3.94Å; V87-V91 WeakPolarHBondContact O-CB 3.44Å; V87-V91 PolarHBondContact O-N 2.89Å; V91-W102 HydrophobicContact CB-CZ2 4.2Å; V91-W102 HydrophobicContact CG1-CZ2 4.38Å; V91-W102 PolarHBondContact O-NE1 3.01Å; V91-V261 HydrophobicContact CG2-CG2 3.75Å
92	F	88.6	Confident	89.8	Confident	30 Å²	30	43.8 Å²	43.8	13%	0.132	21%	0.208	C	C	.	.			trans	-154.4	161.4	177.6	60.9	-85.3	0	0	0	111.3	S90 M94 R98 R259	S90-F92 WeakPolarHBondContact O-CD1 3.41Å; F92-M94 HydrophobicContact CD2-SD 4.39Å; F92-M94 HydrophobicContact CE2-CG 4.44Å; F92-M94 HydrophobicContact CE2-SD 3.48Å; F92-M94 WeakPolarHBondContact CE2-SD 3.17Å; F92-M94 HydrophobicContact CZ-SD 4.12Å; F92-R98 HydrophobicContact CB-CB 4.49Å; F92-R98 HydrophobicContact CB-CG 4.25Å; F92-R98 HydrophobicContact CD1-CB 4.48Å; F92-R98 HydrophobicContact CD1-CG 3.81Å; F92-R98 HydrophobicContact CD2-CB 3.72Å; F92-R98 HydrophobicContact CD2-CG 3.97Å; F92-R98 HydrophobicContact CE1-CG 4.12Å; F92-R98 HydrophobicContact CE2-CB 3.98Å; F92-R98 HydrophobicContact CE2-CG 4.24Å; F92-R98 HydrophobicContact CG-CB 4Å; F92-R98 HydrophobicContact CG-CG 3.75Å; F92-R98 HydrophobicContact CZ-CB 4.5Å; F92-R98 HydrophobicContact CZ-CG 4.33Å; F92-R259 HydrophobicContact CE1-CG 4.43Å; F92-R259 HydrophobicContact CZ-CG 4.44Å
93	S	84.9	Confident	89.9	Confident	50 Å²	50	42.1 Å²	42.1	35%	0.35	20%	0.199	S	C	.	.			trans	-94.2	119.3	173.8	-177.6	0	0	0	0	110.3	R95 F96 G97 S101	S93-R95 PolarHBondContact O-N 2.64Å; S93-R95 PolarHBondContact OG-N 2.66Å; S93-F96 PolarHBondContact O-N 3.21Å; S93-G97 PolarHBondContact O-N 3.38Å; S93-S101 PolarHBondContact N-OG 3.17Å; S93-S101 PolarHBondContact O-OG 3.32Å
94	M	79.2	Confident	90	Very high	55 Å²	55	37.5 Å²	37.5	27%	0.271	18%	0.175	S	C	.	.	T	Hydrogen-bonded Turn	trans	-58.1	-29.9	174.1	-62.9	-71.3	-64.2	0	0	111.7	F92 F96 E252	F92-M94 HydrophobicContact CD2-SD 4.39Å; F92-M94 HydrophobicContact CE2-CG 4.44Å; F92-M94 HydrophobicContact CE2-SD 3.48Å; F92-M94 WeakPolarHBondContact CE2-SD 3.17Å; F92-M94 HydrophobicContact CZ-SD 4.12Å; M94-F96 VanDerWaalsContact C-N 3.34Å; M94-F96 PolarHBondContact O-N 3.25Å; M94-E252 HydrophobicContact CE-CB 3.77Å
95	R	81.1	Confident	90.1	Very high	232 Å²	232	38.8 Å²	38.8	88%	0.875	19%	0.188	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.3	-33.1	-179.3	-171.6	176.8	-179.1	-180	0.9	112.7	S93	S93-R95 PolarHBondContact O-N 2.64Å; S93-R95 PolarHBondContact OG-N 2.66Å
96	F	80.7	Confident	90.2	Very high	116 Å²	116	39 Å²	39	51%	0.509	19%	0.189	S	C	.	.	T	Hydrogen-bonded Turn	trans	-92.8	-20.5	-174.8	-80.6	-81.7	0	0	0	113.2	S93 M94 K100	S93-F96 PolarHBondContact O-N 3.21Å; M94-F96 VanDerWaalsContact C-N 3.34Å; M94-F96 PolarHBondContact O-N 3.25Å; F96-K100 WeakPolarHBondContact O-CB 3.3Å; F96-K100 WeakPolarHBondContact O-CE 3.49Å; F96-K100 PolarHBondContact O-NZ 2.97Å
97	G	85.6	Confident	90.4	Very high	1 Å²	1	39 Å²	39	1%	0.01	19%	0.189	C	C	.	.			trans	98.4	144.6	-166.7	0	0	0	0	0	111.8	S93 R99 S101 E249 E252	S93-G97 PolarHBondContact O-N 3.38Å; G97-R99 PolarHBondContact O-N 3.49Å; G97-S101 VanDerWaalsContact O-CB 3.26Å; G97-S101 WeakPolarHBondContact O-CB 3.3Å; G97-S101 PolarHBondContact O-N 3.19Å; G97-S101 PolarHBondContact O-OG 2.94Å; G97-E249 WeakPolarHBondContact CA-OE1 3.38Å; G97-E252 VanDerWaalsContact CA-OE1 3.3Å; G97-E252 WeakPolarHBondContact CA-OE1 3.48Å
98	R	86.7	Confident	90.6	Very high	9 Å²	9	40.1 Å²	40.1	3%	0.034	19%	0.189	C	C	.	.	T	Hydrogen-bonded Turn	trans	-63.5	-42.4	-176	179.6	165.1	64.7	146.9	-5.7	111.8	F92 E249 F255 P410 V411	F92-R98 HydrophobicContact CB-CB 4.49Å; F92-R98 HydrophobicContact CB-CG 4.25Å; F92-R98 HydrophobicContact CD1-CB 4.48Å; F92-R98 HydrophobicContact CD1-CG 3.81Å; F92-R98 HydrophobicContact CD2-CB 3.72Å; F92-R98 HydrophobicContact CD2-CG 3.97Å; F92-R98 HydrophobicContact CE1-CG 4.12Å; F92-R98 HydrophobicContact CE2-CB 3.98Å; F92-R98 HydrophobicContact CE2-CG 4.24Å; F92-R98 HydrophobicContact CG-CB 4Å; F92-R98 HydrophobicContact CG-CG 3.75Å; F92-R98 HydrophobicContact CZ-CB 4.5Å; F92-R98 HydrophobicContact CZ-CG 4.33Å; R98-E249 PolarHBondContact N-OE2 2.97Å; R98-F255 VanDerWaalsContact NH2-CD1 3.26Å; R98-P410 PolarHBondContact NH2-O 3.17Å; R98-V411 PolarHBondContact NH1-O 3.18Å
99	R	91.4	Very high	90.8	Very high	5 Å²	5	44 Å²	44	2%	0.019	21%	0.209	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.3	-44	-176.9	-53	-55.8	173.1	-162.4	-0.4	111.1	D89 G97 S101 W102 L103 V157 C160 W161 E249	D89-R99 IonicContact OD1-CZ 3.99Å; D89-R99 IonicContact OD1-NH1 3.74Å; D89-R99 PolarHBondContact OD1-NH1 3.22Å; D89-R99 IonicContact OD1-NH2 3.32Å; G97-R99 PolarHBondContact O-N 3.49Å; R99-S101 VanDerWaalsContact C-N 3.27Å; R99-S101 PolarHBondContact O-N 2.73Å; R99-W102 PolarHBondContact O-N 2.8Å; R99-L103 WeakPolarHBondContact O-CB 3.23Å; R99-L103 PolarHBondContact O-N 3.34Å; R99-V157 HydrophobicContact CB-CG1 4.13Å; R99-V157 WeakPolarHBondContact O-CG1 3.3Å; R99-C160 PolarHBondContact NH1-SG 3.46Å; R99-C160 PolarHBondContact NH2-SG 3.33Å; R99-W161 HydrophobicContact CB-CB 4.27Å; R99-W161 HydrophobicContact CB-CD2 3.95Å; R99-W161 HydrophobicContact CB-CG 3.88Å; R99-W161 HydrophobicContact CG-CB 4Å; R99-W161 HydrophobicContact CG-CD2 4.36Å; R99-W161 HydrophobicContact CG-CG 3.77Å; R99-E249 PolarHBondContact N-OE1 3.21Å; R99-E249 PolarHBondContact N-OE2 3.19Å
100	K	92.3	Very high	91.1	Very high	30 Å²	30	44 Å²	44	13%	0.13	21%	0.209	C	C	.	.	H	α-helix	trans	-60.8	-33.8	175.5	-79.2	-175.8	-73.2	170	0	113	F96 W102 L103 I104 K247 E249	F96-K100 WeakPolarHBondContact O-CB 3.3Å; F96-K100 WeakPolarHBondContact O-CE 3.49Å; F96-K100 PolarHBondContact O-NZ 2.97Å; K100-W102 PolarHBondContact O-N 3.27Å; K100-W102 VanDerWaalsContact O-N 3.1Å; K100-L103 PolarHBondContact O-N 2.82Å; K100-I104 HydrophobicContact CB-CG1 4.03Å; K100-I104 HydrophobicContact CG-CG1 4.14Å; K100-I104 WeakPolarHBondContact O-CB 3.3Å; K100-I104 WeakPolarHBondContact O-CG1 3.43Å; K100-I104 PolarHBondContact O-N 3.18Å; K100-I104 VanDerWaalsContact O-N 3.08Å; K100-K247 WeakPolarHBondContact CE-O 3.24Å; K100-K247 PolarHBondContact NZ-O 3.14Å; K100-K247 VanDerWaalsContact NZ-O 3.08Å; K100-E249 WeakPolarHBondContact CB-OE1 3.32Å; K100-E249 WeakPolarHBondContact CE-OE1 3.33Å; K100-E249 WeakPolarHBondContact CG-OE1 3.39Å; K100-E249 PolarHBondContact N-OE1 3.33Å
101	S	93.3	Very high	91.4	Very high	23 Å²	23	43.9 Å²	43.9	16%	0.161	21%	0.209	C	C	.	.	H	α-helix	trans	-54.1	-30.3	176.5	-70.8	0	0	0	0	113.5	S93 G97 R99 P105	S93-S101 PolarHBondContact N-OG 3.17Å; S93-S101 PolarHBondContact O-OG 3.32Å; G97-S101 VanDerWaalsContact O-CB 3.26Å; G97-S101 WeakPolarHBondContact O-CB 3.3Å; G97-S101 PolarHBondContact O-N 3.19Å; G97-S101 PolarHBondContact O-OG 2.94Å; R99-S101 VanDerWaalsContact C-N 3.27Å; R99-S101 PolarHBondContact O-N 2.73Å; S101-P105 WeakPolarHBondContact O-CD 3.26Å; S101-P105 WeakPolarHBondContact O-CG 3.41Å
102	W	95	Very high	91.6	Very high	71 Å²	71	45.1 Å²	45.1	27%	0.269	21%	0.213	S	C	.	.	H	α-helix	trans	-108	-38.5	176.5	-74.5	99.2	0	0	0	113.3	V88 V91 R99 K100 I104 T106 T153 V157	V88-W102 HydrophobicContact CG1-CB 4.34Å; V88-W102 HydrophobicContact CG1-CD2 4.32Å; V88-W102 HydrophobicContact CG1-CG 3.93Å; V88-W102 HydrophobicContact CG2-CD2 4.34Å; V88-W102 PolarHBondContact O-NE1 3.48Å; V91-W102 HydrophobicContact CB-CZ2 4.2Å; V91-W102 HydrophobicContact CG1-CZ2 4.38Å; V91-W102 PolarHBondContact O-NE1 3.01Å; R99-W102 PolarHBondContact O-N 2.8Å; K100-W102 PolarHBondContact O-N 3.27Å; K100-W102 VanDerWaalsContact O-N 3.1Å; W102-I104 PolarHBondContact O-N 2.93Å; W102-T106 WeakPolarHBondContact O-CB 3.5Å; W102-T106 PolarHBondContact O-N 2.94Å; W102-T106 VanDerWaalsContact O-N 3.08Å; W102-T106 PolarHBondContact O-OG1 2.88Å; W102-T153 HydrophobicContact CE3-CG2 4.01Å; W102-V157 HydrophobicContact CB-CG2 3.48Å; W102-V157 VanDerWaalsContact CB-CG2 3.48Å; W102-V157 HydrophobicContact CG-CG2 4.36Å
103	L	95.6	Very high	91.9	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-60.7	-49.4	-177.8	-175.8	67.7	0	0	0	111.2	L40 R99 K100 T106 Q107 Q154 V157 V158 W161 V243	L40-L103 HydrophobicContact CD1-CD2 4.3Å; L40-L103 HydrophobicContact CD2-CD2 4.27Å; R99-L103 WeakPolarHBondContact O-CB 3.23Å; R99-L103 PolarHBondContact O-N 3.34Å; K100-L103 PolarHBondContact O-N 2.82Å; L103-T106 PolarHBondContact O-N 2.65Å; L103-Q107 HydrophobicContact CD1-CG 3.9Å; L103-Q107 HydrophobicContact CG-CG 4.24Å; L103-Q107 WeakPolarHBondContact O-CB 3.48Å; L103-Q107 WeakPolarHBondContact O-CG 3.3Å; L103-Q107 PolarHBondContact O-N 2.96Å; L103-Q154 HydrophobicContact CD1-CG 3.91Å; L103-V157 HydrophobicContact CB-CG1 3.87Å; L103-V158 HydrophobicContact CD1-CG2 3.83Å; L103-W161 HydrophobicContact CD2-CE3 3.73Å; L103-W161 HydrophobicContact CD2-CH2 4.19Å; L103-W161 HydrophobicContact CD2-CZ3 3.25Å; L103-V243 HydrophobicContact CD2-CG1 4.22Å
104	I	96.3	Very high	92.2	Very high	15 Å²	15	42.7 Å²	42.7	8%	0.077	20%	0.196	C	C	.	.	H	α-helix	trans	-64.9	-52.5	-172.8	-60.7	-59.2	0	0	0	111.3	K100 W102 T106 Q107 Y108 T240 V243 L244	K100-I104 HydrophobicContact CB-CG1 4.03Å; K100-I104 HydrophobicContact CG-CG1 4.14Å; K100-I104 WeakPolarHBondContact O-CB 3.3Å; K100-I104 WeakPolarHBondContact O-CG1 3.43Å; K100-I104 PolarHBondContact O-N 3.18Å; K100-I104 VanDerWaalsContact O-N 3.08Å; W102-I104 PolarHBondContact O-N 2.93Å; I104-T106 VanDerWaalsContact C-N 3.33Å; I104-T106 PolarHBondContact O-N 2.86Å; I104-Q107 PolarHBondContact O-N 3.45Å; I104-Y108 HydrophobicContact CG2-CD2 3.68Å; I104-Y108 HydrophobicContact CG2-CE2 3.45Å; I104-Y108 VanDerWaalsContact CG2-CE2 3.45Å; I104-Y108 VanDerWaalsContact O-CD2 3.25Å; I104-Y108 WeakPolarHBondContact O-CD2 3.27Å; I104-Y108 PolarHBondContact O-N 3.38Å; I104-T240 HydrophobicContact CB-CG2 4.22Å; I104-T240 HydrophobicContact CD1-CG2 3.67Å; I104-T240 WeakPolarHBondContact CD1-O 3.33Å; I104-T240 HydrophobicContact CG2-CG2 3.83Å; I104-V243 HydrophobicContact CD1-CB 4.26Å; I104-V243 HydrophobicContact CD1-CG1 4.06Å; I104-L244 HydrophobicContact CD1-CB 4.01Å; I104-L244 HydrophobicContact CG1-CB 4.48Å; I104-L244 HydrophobicContact CG1-CD1 4.36Å
105	P	96.5	Very high	92.8	Very high	63 Å²	63	43 Å²	43	41%	0.409	20%	0.198	S	C	.	.	H	α-helix	trans	-60.3	-42.9	175.6	-24.5	36	0	0	0	112.5	S101 Q107 Y108 L109	S101-P105 WeakPolarHBondContact O-CD 3.26Å; S101-P105 WeakPolarHBondContact O-CG 3.41Å; P105-Q107 PolarHBondContact O-N 3.19Å; P105-Y108 PolarHBondContact O-N 2.73Å; P105-L109 WeakPolarHBondContact O-CB 3.24Å; P105-L109 WeakPolarHBondContact O-CG 3.21Å; P105-L109 PolarHBondContact O-N 2.85Å
106	T	96.9	Very high	93.3	Very high	5 Å²	5	36.2 Å²	36.2	3%	0.031	18%	0.175	C	C	.	.	H	α-helix	trans	-64.3	-44.6	-177.2	-57	0	0	0	0	111.5	W102 L103 I104 L109 I110 L150 Q154	W102-T106 WeakPolarHBondContact O-CB 3.5Å; W102-T106 PolarHBondContact O-N 2.94Å; W102-T106 VanDerWaalsContact O-N 3.08Å; W102-T106 PolarHBondContact O-OG1 2.88Å; L103-T106 PolarHBondContact O-N 2.65Å; I104-T106 VanDerWaalsContact C-N 3.33Å; I104-T106 PolarHBondContact O-N 2.86Å; T106-L109 PolarHBondContact O-N 3.48Å; T106-I110 HydrophobicContact CG2-CD1 4.05Å; T106-I110 VanDerWaalsContact O-CG1 3.25Å; T106-I110 WeakPolarHBondContact O-CG1 3.33Å; T106-I110 PolarHBondContact O-N 3.11Å; T106-L150 HydrophobicContact CG2-CB 3.99Å; T106-L150 HydrophobicContact CG2-CD2 4.25Å; T106-L150 WeakPolarHBondContact CG2-O 3.41Å; T106-Q154 HydrophobicContact CG2-CB 4.03Å
107	Q	96.9	Very high	93.6	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-67.8	-39.2	178.3	-72.2	-170.5	-48.8	0	0	112.8	L103 I104 P105 L109 I110 G111 Q154 F236 T240	L103-Q107 HydrophobicContact CD1-CG 3.9Å; L103-Q107 HydrophobicContact CG-CG 4.24Å; L103-Q107 WeakPolarHBondContact O-CB 3.48Å; L103-Q107 WeakPolarHBondContact O-CG 3.3Å; L103-Q107 PolarHBondContact O-N 2.96Å; I104-Q107 PolarHBondContact O-N 3.45Å; P105-Q107 PolarHBondContact O-N 3.19Å; Q107-L109 VanDerWaalsContact C-N 3.33Å; Q107-I110 PolarHBondContact O-N 2.99Å; Q107-G111 PolarHBondContact O-N 3Å; Q107-Q154 HydrophobicContact CG-CG 4.45Å; Q107-F236 HydrophobicContact CB-CD1 4.13Å; Q107-F236 HydrophobicContact CG-CD1 4.44Å; Q107-F236 HydrophobicContact CG-CE1 4.48Å; Q107-T240 HydrophobicContact CB-CG2 4.04Å; Q107-T240 WeakPolarHBondContact CB-OG1 3.3Å; Q107-T240 PolarHBondContact OE1-OG1 3.46Å
108	Y	98.1	Very high	93.6	Very high	64 Å²	64	31.9 Å²	31.9	25%	0.251	16%	0.158	S	C	.	.	H	α-helix	trans	-62.9	-40.2	172.3	-78.1	-46.5	0	0	0	112.3	I104 P105 G111 L112 F237 T240 T241	I104-Y108 HydrophobicContact CG2-CD2 3.68Å; I104-Y108 HydrophobicContact CG2-CE2 3.45Å; I104-Y108 VanDerWaalsContact CG2-CE2 3.45Å; I104-Y108 VanDerWaalsContact O-CD2 3.25Å; I104-Y108 WeakPolarHBondContact O-CD2 3.27Å; I104-Y108 PolarHBondContact O-N 3.38Å; P105-Y108 PolarHBondContact O-N 2.73Å; Y108-G111 PolarHBondContact O-N 3.02Å; Y108-L112 WeakPolarHBondContact O-CB 3.29Å; Y108-L112 PolarHBondContact O-N 2.89Å; Y108-F237 AromaticContact CD1-CD1 3.43Å; Y108-F237 HydrophobicContact CD1-CD1 3.43Å; Y108-F237 VanDerWaalsContact CD1-CD1 3.43Å; Y108-F237 AromaticContact CD1-CE1 3.86Å; Y108-F237 HydrophobicContact CD1-CE1 3.86Å; Y108-F237 AromaticContact CE1-CD1 3.81Å; Y108-F237 HydrophobicContact CE1-CD1 3.81Å; Y108-T240 HydrophobicContact CD1-CG2 3.85Å; Y108-T240 HydrophobicContact CD2-CG2 3.68Å; Y108-T240 HydrophobicContact CE1-CG2 3.74Å; Y108-T240 HydrophobicContact CE2-CG2 3.55Å; Y108-T240 HydrophobicContact CG-CG2 3.84Å; Y108-T241 WeakPolarHBondContact OH-CA 3.48Å; Y108-T241 PolarHBondContact OH-OG1 3.47Å
109	L	97.4	Very high	93.4	Very high	84 Å²	84	35.2 Å²	35.2	44%	0.44	18%	0.183	S	C	.	.	H	α-helix	trans	-65.4	-39.4	175.3	-71.9	170.9	0	0	0	111.8	P105 T106 Q107 L112 F113 L150	P105-L109 WeakPolarHBondContact O-CB 3.24Å; P105-L109 WeakPolarHBondContact O-CG 3.21Å; P105-L109 PolarHBondContact O-N 2.85Å; T106-L109 PolarHBondContact O-N 3.48Å; Q107-L109 VanDerWaalsContact C-N 3.33Å; L109-L112 PolarHBondContact O-N 3.3Å; L109-F113 VanDerWaalsContact O-CB 3.22Å; L109-F113 WeakPolarHBondContact O-CB 3.06Å; L109-F113 PolarHBondContact O-N 2.93Å; L109-L150 HydrophobicContact CB-CD1 3.71Å; L109-L150 HydrophobicContact CB-CD2 3.98Å; L109-L150 HydrophobicContact CB-CG 4.49Å; L109-L150 HydrophobicContact CD1-CD2 3.84Å
110	I	96.8	Very high	92.9	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-62.1	-45.9	173.1	-69	166.7	0	0	0	110.5	P47 T106 Q107 F113 M114 F147 L150 Q154 F236	P47-I110 HydrophobicContact CG-CG2 3.87Å; T106-I110 HydrophobicContact CG2-CD1 4.05Å; T106-I110 VanDerWaalsContact O-CG1 3.25Å; T106-I110 WeakPolarHBondContact O-CG1 3.33Å; T106-I110 PolarHBondContact O-N 3.11Å; Q107-I110 PolarHBondContact O-N 2.99Å; I110-F113 WeakPolarHBondContact O-CB 3.34Å; I110-F113 PolarHBondContact O-N 3.49Å; I110-M114 HydrophobicContact CG2-CE 3.88Å; I110-M114 HydrophobicContact CG2-SD 4.46Å; I110-M114 WeakPolarHBondContact O-CG 3.2Å; I110-M114 PolarHBondContact O-N 3.47Å; I110-F147 HydrophobicContact CG2-CE2 3.86Å; I110-L150 HydrophobicContact CD1-CB 4.11Å; I110-L150 HydrophobicContact CG1-CB 3.62Å; I110-L150 HydrophobicContact CG1-CD1 4.26Å; I110-Q154 HydrophobicContact CD1-CB 4.36Å; I110-F236 HydrophobicContact CB-CD1 4.12Å; I110-F236 HydrophobicContact CB-CE1 3.91Å; I110-F236 HydrophobicContact CB-CZ 4.47Å; I110-F236 HydrophobicContact CD1-CE1 4.25Å; I110-F236 HydrophobicContact CG2-CD1 3.86Å; I110-F236 HydrophobicContact CG2-CD2 4.44Å; I110-F236 HydrophobicContact CG2-CE1 3.38Å; I110-F236 HydrophobicContact CG2-CE2 4.05Å; I110-F236 HydrophobicContact CG2-CG 4.34Å; I110-F236 HydrophobicContact CG2-CZ 3.47Å; I110-F236 VanDerWaalsContact CG2-CZ 3.47Å
111	G	96.1	Very high	91.9	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-62	-44.2	176.8	0	0	0	0	0	112.7	Q107 Y108 F113 M114 L115 A233	Q107-G111 PolarHBondContact O-N 3Å; Y108-G111 PolarHBondContact O-N 3.02Å; G111-F113 VanDerWaalsContact C-N 3.3Å; G111-F113 PolarHBondContact O-N 3.36Å; G111-M114 PolarHBondContact O-N 3.37Å; G111-L115 WeakPolarHBondContact O-CB 3.27Å; G111-L115 PolarHBondContact O-N 2.95Å; G111-A233 VanDerWaalsContact O-CB 3.31Å; G111-A233 WeakPolarHBondContact O-CB 3.47Å
112	L	95.5	Very high	90.5	Very high	95 Å²	95	41.1 Å²	41.1	50%	0.497	21%	0.21	S	C	.	.	H	α-helix	trans	-62.2	-39.5	174.4	-179	62.5	0	0	0	111.6	Y108 L109 L115 F116 F237	Y108-L112 WeakPolarHBondContact O-CB 3.29Å; Y108-L112 PolarHBondContact O-N 2.89Å; L109-L112 PolarHBondContact O-N 3.3Å; L112-L115 PolarHBondContact O-N 3.44Å; L112-F116 WeakPolarHBondContact O-CB 3.34Å; L112-F116 PolarHBondContact O-N 2.88Å; L112-F237 HydrophobicContact CB-CZ 4.21Å
113	F	93.4	Very high	89.2	Confident	29 Å²	29	41.9 Å²	41.9	13%	0.127	23%	0.226	C	C	.	.	H	α-helix	trans	-64.3	-42.9	176.1	-167.7	-80.4	0	0	0	111.6	L109 I110 G111 F116 L117 I143 F147	L109-F113 VanDerWaalsContact O-CB 3.22Å; L109-F113 WeakPolarHBondContact O-CB 3.06Å; L109-F113 PolarHBondContact O-N 2.93Å; I110-F113 WeakPolarHBondContact O-CB 3.34Å; I110-F113 PolarHBondContact O-N 3.49Å; G111-F113 VanDerWaalsContact C-N 3.3Å; G111-F113 PolarHBondContact O-N 3.36Å; F113-F116 PolarHBondContact O-N 3.31Å; F113-L117 HydrophobicContact CD1-CD1 3.78Å; F113-L117 HydrophobicContact CD1-CG 3.84Å; F113-L117 HydrophobicContact CE1-CD1 3.47Å; F113-L117 VanDerWaalsContact CE1-CD1 3.47Å; F113-L117 HydrophobicContact CE1-CD2 4.06Å; F113-L117 HydrophobicContact CE1-CG 3.62Å; F113-L117 WeakPolarHBondContact O-CB 3.36Å; F113-L117 WeakPolarHBondContact O-CG 3.26Å; F113-L117 PolarHBondContact O-N 3.35Å; F113-I143 HydrophobicContact CE1-CG2 4.1Å; F113-I143 HydrophobicContact CE2-CG2 3.92Å; F113-I143 WeakPolarHBondContact CE2-O 3.27Å; F113-I143 HydrophobicContact CZ-CB 4.26Å; F113-I143 HydrophobicContact CZ-CG2 3.24Å; F113-I143 WeakPolarHBondContact CZ-O 3.11Å; F113-F147 HydrophobicContact CB-CD2 4.07Å; F113-F147 HydrophobicContact CB-CE2 4.32Å; F113-F147 HydrophobicContact CD1-CB 4Å; F113-F147 HydrophobicContact CD1-CD1 4.42Å; F113-F147 AromaticContact CD1-CD2 3.15Å; F113-F147 HydrophobicContact CD1-CD2 3.15Å; F113-F147 AromaticContact CD1-CE2 3.58Å; F113-F147 HydrophobicContact CD1-CE2 3.58Å; F113-F147 AromaticContact CD1-CG 3.64Å; F113-F147 HydrophobicContact CD1-CG 3.64Å; F113-F147 HydrophobicContact CD1-CZ 4.37Å; F113-F147 HydrophobicContact CD2-CD2 4.4Å; F113-F147 HydrophobicContact CE1-CB 3.49Å; F113-F147 VanDerWaalsContact CE1-CB 3.49Å; F113-F147 HydrophobicContact CE1-CD1 4.1Å; F113-F147 AromaticContact CE1-CD2 3.53Å; F113-F147 HydrophobicContact CE1-CD2 3.53Å; F113-F147 HydrophobicContact CE1-CE2 4.2Å; F113-F147 AromaticContact CE1-CG 3.46Å; F113-F147 HydrophobicContact CE1-CG 3.46Å; F113-F147 VanDerWaalsContact CE1-CG 3.46Å; F113-F147 HydrophobicContact CE2-CB 4.07Å; F113-F147 HydrophobicContact CG-CB 4.46Å; F113-F147 AromaticContact CG-CD2 3.63Å; F113-F147 HydrophobicContact CG-CD2 3.63Å; F113-F147 HydrophobicContact CG-CE2 4.21Å; F113-F147 HydrophobicContact CG-CG 4.33Å; F113-F147 HydrophobicContact CZ-CB 3.52Å; F113-F147 HydrophobicContact CZ-CD2 4.29Å; F113-F147 HydrophobicContact CZ-CG 4.04Å
114	M	92.1	Very high	87.7	Confident	0 Å²	0	44.4 Å²	44.4	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-63.9	-39.8	174.1	-71	179.5	177.8	0	0	112.1	I46 P47 L50 I110 G111 L117 S118 F147 W232 A233 F236	I46-M114 HydrophobicContact CB-CE 4.37Å; I46-M114 HydrophobicContact CG2-CE 3.63Å; P47-M114 HydrophobicContact CG-CE 3.91Å; L50-M114 HydrophobicContact CD1-CE 3.95Å; I110-M114 HydrophobicContact CG2-CE 3.88Å; I110-M114 HydrophobicContact CG2-SD 4.46Å; I110-M114 WeakPolarHBondContact O-CG 3.2Å; I110-M114 PolarHBondContact O-N 3.47Å; G111-M114 PolarHBondContact O-N 3.37Å; M114-L117 PolarHBondContact O-N 3.4Å; M114-S118 WeakPolarHBondContact O-CB 3.38Å; M114-S118 PolarHBondContact O-N 3.01Å; M114-F147 HydrophobicContact CE-CE2 4.18Å; M114-F147 HydrophobicContact CE-CZ 3.71Å; M114-F147 HydrophobicContact CG-CE2 4.13Å; M114-F147 HydrophobicContact CG-CZ 4.12Å; M114-W232 HydrophobicContact SD-CB 3.62Å; M114-A233 HydrophobicContact CB-CB 3.98Å; M114-F236 HydrophobicContact CE-CD2 4.12Å; M114-F236 HydrophobicContact CE-CE2 3.5Å; M114-F236 HydrophobicContact CE-CZ 4.07Å; M114-F236 HydrophobicContact SD-CD2 3.76Å; M114-F236 HydrophobicContact SD-CE2 3.78Å
115	L	92.1	Very high	86	Confident	61 Å²	61	45.8 Å²	45.8	32%	0.319	25%	0.245	S	C	.	.	H	α-helix	trans	-63.3	-42.7	174.3	-178.5	61.9	0	0	0	111.5	G111 L112 S118 S119 Y230 A233 F237	G111-L115 WeakPolarHBondContact O-CB 3.27Å; G111-L115 PolarHBondContact O-N 2.95Å; L112-L115 PolarHBondContact O-N 3.44Å; L115-S118 WeakPolarHBondContact O-CB 3.32Å; L115-S118 PolarHBondContact O-N 3.22Å; L115-S119 PolarHBondContact O-N 3.48Å; L115-Y230 HydrophobicContact CD1-CD2 3.49Å; L115-Y230 VanDerWaalsContact CD1-CD2 3.49Å; L115-Y230 HydrophobicContact CD1-CE2 3.71Å; L115-A233 HydrophobicContact CB-CB 3.96Å; L115-F237 HydrophobicContact CD2-CE2 4.33Å
116	F	90.1	Very high	83.8	Confident	89 Å²	89	43.7 Å²	43.7	39%	0.39	24%	0.235	S	C	.	.	H	α-helix	trans	-62.7	-49.5	174.6	172.3	-100.3	0	0	0	111.4	L112 F113 S118 S119 K120 F124	L112-F116 WeakPolarHBondContact O-CB 3.34Å; L112-F116 PolarHBondContact O-N 2.88Å; F113-F116 PolarHBondContact O-N 3.31Å; F116-S118 VanDerWaalsContact C-N 3.27Å; F116-S118 PolarHBondContact O-N 3.31Å; F116-S119 PolarHBondContact O-N 2.71Å; F116-S119 VanDerWaalsContact O-N 3.12Å; F116-S119 PolarHBondContact O-OG 3.23Å; F116-K120 HydrophobicContact CD2-CG 4.34Å; F116-K120 HydrophobicContact CE1-CG 4.19Å; F116-K120 HydrophobicContact CE2-CG 3.84Å; F116-K120 HydrophobicContact CZ-CG 3.76Å; F116-K120 PolarHBondContact O-N 3.04Å; F116-F124 HydrophobicContact CE1-CE2 4.48Å
117	L	87.2	Confident	81.5	Confident	11 Å²	11	48.9 Å²	48.9	6%	0.058	26%	0.262	C	S	.	.	H	α-helix	trans	-56.5	-43.9	176.2	-76.7	-174.8	0	0	0	110.9	F113 M114 S119 K120 V121 F124 I143 F144 L229	F113-L117 HydrophobicContact CD1-CD1 3.78Å; F113-L117 HydrophobicContact CD1-CG 3.84Å; F113-L117 HydrophobicContact CE1-CD1 3.47Å; F113-L117 VanDerWaalsContact CE1-CD1 3.47Å; F113-L117 HydrophobicContact CE1-CD2 4.06Å; F113-L117 HydrophobicContact CE1-CG 3.62Å; F113-L117 WeakPolarHBondContact O-CB 3.36Å; F113-L117 WeakPolarHBondContact O-CG 3.26Å; F113-L117 PolarHBondContact O-N 3.35Å; M114-L117 PolarHBondContact O-N 3.4Å; L117-S119 VanDerWaalsContact C-N 3.29Å; L117-S119 PolarHBondContact O-N 3.33Å; L117-K120 CarbonylContact O-C 3.58Å; L117-K120 PolarHBondContact O-N 3.2Å; L117-V121 WeakPolarHBondContact O-CG2 3.42Å; L117-V121 PolarHBondContact O-N 3.34Å; L117-F124 HydrophobicContact CD2-CD2 4.36Å; L117-F124 HydrophobicContact CD2-CE2 4.04Å; L117-I143 HydrophobicContact CD2-CG2 4.16Å; L117-F144 HydrophobicContact CD1-CZ 4.13Å; L117-L229 HydrophobicContact CB-CD1 3.87Å
118	S	85.9	Confident	79.1	Confident	15 Å²	15	56.3 Å²	56.3	11%	0.105	30%	0.297	C	S	.	.	H	α-helix	trans	-51.4	-45.6	175.8	177.5	0	0	0	0	112.4	M114 L115 F116 K120 A226	M114-S118 WeakPolarHBondContact O-CB 3.38Å; M114-S118 PolarHBondContact O-N 3.01Å; L115-S118 WeakPolarHBondContact O-CB 3.32Å; L115-S118 PolarHBondContact O-N 3.22Å; F116-S118 VanDerWaalsContact C-N 3.27Å; F116-S118 PolarHBondContact O-N 3.31Å; S118-K120 VanDerWaalsContact C-N 3.3Å; S118-K120 PolarHBondContact O-N 2.84Å; S118-A226 WeakPolarHBondContact CB-O 3.45Å; S118-A226 VanDerWaalsContact O-CB 3.26Å; S118-A226 WeakPolarHBondContact O-CB 3.46Å; S118-A226 VanDerWaalsContact OG-C 3.28Å; S118-A226 WeakPolarHBondContact OG-CA 3.34Å; S118-A226 PolarHBondContact OG-O 3.05Å
119	S	83.2	Confident	76.4	Confident	79 Å²	79	56.6 Å²	56.6	55%	0.552	32%	0.319	S	S	*	.	H	α-helix	trans	-73.2	-18.6	178.4	73.5	0	0	0	0	114.9	L115 F116 L117	L115-S119 PolarHBondContact O-N 3.48Å; F116-S119 PolarHBondContact O-N 2.71Å; F116-S119 VanDerWaalsContact O-N 3.12Å; F116-S119 PolarHBondContact O-OG 3.23Å; L117-S119 VanDerWaalsContact C-N 3.29Å; L117-S119 PolarHBondContact O-N 3.33Å
120	K	80.2	Confident	73.9	Confident	90 Å²	90	54.5 Å²	54.5	39%	0.391	31%	0.314	S	S	.	.	H	α-helix	trans	-110.8	-0	-176.1	-65	-61.6	-175.3	-177.4	0	113.2	F116 L117 S118 D122 S123 F124	F116-K120 HydrophobicContact CD2-CG 4.34Å; F116-K120 HydrophobicContact CE1-CG 4.19Å; F116-K120 HydrophobicContact CE2-CG 3.84Å; F116-K120 HydrophobicContact CZ-CG 3.76Å; F116-K120 PolarHBondContact O-N 3.04Å; L117-K120 CarbonylContact O-C 3.58Å; L117-K120 PolarHBondContact O-N 3.2Å; S118-K120 VanDerWaalsContact C-N 3.3Å; S118-K120 PolarHBondContact O-N 2.84Å; K120-D122 PolarHBondContact O-N 2.85Å; K120-S123 CarbonylContact O-C 3.47Å; K120-S123 WeakPolarHBondContact O-CA 3.47Å; K120-S123 WeakPolarHBondContact O-CB 3.4Å; K120-S123 PolarHBondContact O-N 3.19Å; K120-F124 HydrophobicContact CB-CD2 3.57Å; K120-F124 HydrophobicContact CB-CE2 3.35Å; K120-F124 HydrophobicContact CB-CZ 4.34Å; K120-F124 HydrophobicContact CG-CE2 4.24Å; K120-F124 WeakPolarHBondContact O-CD2 3.34Å; K120-F124 PolarHBondContact O-N 3.17Å
121	V	70.6	Confident	71.4	Confident	6 Å²	6	63.8 Å²	63.8	4%	0.036	36%	0.357	C	S	.	.	H	α-helix	trans	-49.8	-47.7	175.9	174.3	0	0	0	0	109.6	L117 S123 F124 L125 L222 A225 A226 L229	L117-V121 WeakPolarHBondContact O-CG2 3.42Å; L117-V121 PolarHBondContact O-N 3.34Å; V121-S123 VanDerWaalsContact C-N 3.26Å; V121-S123 PolarHBondContact O-N 3.47Å; V121-F124 PolarHBondContact O-N 2.95Å; V121-F124 VanDerWaalsContact O-N 3.1Å; V121-L125 HydrophobicContact CG1-CD1 3.56Å; V121-L125 HydrophobicContact CG1-CG 4.46Å; V121-L125 VanDerWaalsContact O-CB 3.3Å; V121-L125 WeakPolarHBondContact O-CB 3.12Å; V121-L125 PolarHBondContact O-N 3.04Å; V121-L222 HydrophobicContact CG1-CB 4.2Å; V121-L222 HydrophobicContact CG1-CD2 3.81Å; V121-A225 HydrophobicContact CG1-CB 3.87Å; V121-A226 HydrophobicContact CB-CB 4.35Å; V121-A226 HydrophobicContact CG2-CB 4.16Å; V121-L229 HydrophobicContact CG2-CD1 3.63Å
122	D	65.6	Low	68.8	Low	86 Å²	86	71 Å²	71	46%	0.46	40%	0.396	S	S	.	.	H	α-helix	trans	-59.7	-35.4	178.6	-62.6	-37.1	0	0	0	113.1	K120 G126 L222	K120-D122 PolarHBondContact O-N 2.85Å; D122-G126 WeakPolarHBondContact O-CA 3.29Å; D122-G126 PolarHBondContact O-N 3.32Å; D122-L222 WeakPolarHBondContact OD1-CB 3.47Å; D122-L222 WeakPolarHBondContact OD1-CD1 3.12Å
123	S	67.2	Low	66.5	Low	87 Å²	87	68.9 Å²	68.9	61%	0.608	39%	0.389	S	S	*	.	H	α-helix	trans	-78.5	-29.2	177.5	-179.1	0	0	0	0	112.9	K120 V121	K120-S123 CarbonylContact O-C 3.47Å; K120-S123 WeakPolarHBondContact O-CA 3.47Å; K120-S123 WeakPolarHBondContact O-CB 3.4Å; K120-S123 PolarHBondContact O-N 3.19Å; V121-S123 VanDerWaalsContact C-N 3.26Å; V121-S123 PolarHBondContact O-N 3.47Å
124	F	64	Low	64.3	Low	54 Å²	54	72.9 Å²	72.9	24%	0.237	42%	0.42	C	S	.	.	H	α-helix	trans	-89.3	-25.3	-179	-71.7	-55.7	0	0	0	113.2	F116 L117 K120 V121 H135 L140 I143	F116-F124 HydrophobicContact CE1-CE2 4.48Å; L117-F124 HydrophobicContact CD2-CD2 4.36Å; L117-F124 HydrophobicContact CD2-CE2 4.04Å; K120-F124 HydrophobicContact CB-CD2 3.57Å; K120-F124 HydrophobicContact CB-CE2 3.35Å; K120-F124 HydrophobicContact CB-CZ 4.34Å; K120-F124 HydrophobicContact CG-CE2 4.24Å; K120-F124 WeakPolarHBondContact O-CD2 3.34Å; K120-F124 PolarHBondContact O-N 3.17Å; V121-F124 PolarHBondContact O-N 2.95Å; V121-F124 VanDerWaalsContact O-N 3.1Å; F124-H135 PolarHBondContact O-NE2 2.91Å; F124-L140 HydrophobicContact CD1-CD1 4.2Å; F124-L140 HydrophobicContact CE1-CD1 4.42Å; F124-I143 HydrophobicContact CE1-CD1 4.21Å; F124-I143 HydrophobicContact CZ-CD1 3.69Å
125	L	60.3	Low	62.7	Low	44 Å²	44	75.9 Å²	75.9	23%	0.23	43%	0.434	C	S	.	.	H	α-helix	trans	-120.3	5	-177.1	-66.9	169.7	0	0	0	112.2	V57 R61 V121 L222	V57-L125 HydrophobicContact CG1-CD2 3.48Å; V57-L125 VanDerWaalsContact CG1-CD2 3.48Å; R61-L125 VanDerWaalsContact NH2-C 3.35Å; R61-L125 PolarHBondContact NH2-O 3.26Å; V121-L125 HydrophobicContact CG1-CD1 3.56Å; V121-L125 HydrophobicContact CG1-CG 4.46Å; V121-L125 VanDerWaalsContact O-CB 3.3Å; V121-L125 WeakPolarHBondContact O-CB 3.12Å; V121-L125 PolarHBondContact O-N 3.04Å; L125-L222 HydrophobicContact CB-CD2 3.16Å; L125-L222 HydrophobicContact CD1-CD2 4.05Å; L125-L222 HydrophobicContact CG-CD2 4.23Å
126	G	49.6	Very low	61.7	Low	19 Å²	19	76.2 Å²	76.2	20%	0.196	44%	0.437	C	S	.	.			trans	-73.1	158.7	177.6	0	0	0	0	0	115.1	R61 D122	R61-G126 PolarHBondContact NH1-O 3.36Å; D122-G126 WeakPolarHBondContact O-CA 3.29Å; D122-G126 PolarHBondContact O-N 3.32Å
127	D	49.8	Very low	61.2	Low	113 Å²	113	73.3 Å²	73.3	60%	0.604	43%	0.425	S	S	*	.			trans	33.1	96.2	-175.1	-84.2	-13.8	0	0	0	118.7	G129 A130	D127-G129 PolarHBondContact O-N 3.07Å; D127-G129 VanDerWaalsContact O-N 3.12Å; D127-A130 HydrophobicContact CB-CB 3.85Å; D127-A130 PolarHBondContact O-N 3.08Å
128	E	45.9	Very low	61	Low	157 Å²	157	80.5 Å²	80.5	73%	0.734	46%	0.456	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.3	-16.2	160.4	-67.1	-175.4	161.8	0	0	112.8
129	G	42.3	Very low	61.1	Low	70 Å²	70	85.9 Å²	85.9	72%	0.722	48%	0.477	S	S	*	.	T	Hydrogen-bonded Turn	trans	-96.5	-7.2	-179.9	0	0	0	0	0	115.9	D127 E131	D127-G129 PolarHBondContact O-N 3.07Å; D127-G129 VanDerWaalsContact O-N 3.12Å; G129-E131 PolarHBondContact O-N 3.01Å
130	A	44.8	Very low	61.1	Low	39 Å²	39	82.8 Å²	82.8	32%	0.322	46%	0.455	S	S	.	.			trans	-94.5	81	179.7	0	0	0	0	0	110.2	D127 N132 S133	D127-A130 HydrophobicContact CB-CB 3.85Å; D127-A130 PolarHBondContact O-N 3.08Å; A130-N132 PolarHBondContact O-N 3.4Å; A130-S133 PolarHBondContact O-N 2.97Å; A130-S133 PolarHBondContact O-OG 3.36Å
131	E	44.2	Very low	61.5	Low	195 Å²	195	79.3 Å²	79.3	91%	0.911	44%	0.441	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49.4	-22.1	170.8	-70.9	-172.4	155.9	0	0	113	G129	G129-E131 PolarHBondContact O-N 3.01Å
132	N	39.9	Very low	62.5	Low	153 Å²	153	81.2 Å²	81.2	82%	0.818	46%	0.458	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.1	8.7	-179.1	-75.7	-22.7	0	0	0	115.4	A130 S134	A130-N132 PolarHBondContact O-N 3.4Å; N132-S134 PolarHBondContact O-N 2.82Å
133	S	47.6	Very low	63.7	Low	49 Å²	49	78.9 Å²	78.9	34%	0.343	44%	0.444	S	S	.	.			trans	-73.1	82.6	164	51.4	0	0	0	0	107.6	A130 H135	A130-S133 PolarHBondContact O-N 2.97Å; A130-S133 PolarHBondContact O-OG 3.36Å; S133-H135 PolarHBondContact O-N 2.96Å; S133-H135 PolarHBondContact O-ND1 3.49Å; S133-H135 PolarHBondContact OG-CE1 2.88Å; S133-H135 VanDerWaalsContact OG-CE1 3.29Å
134	S	48.6	Very low	64.8	Low	113 Å²	113	75.1 Å²	75.1	79%	0.79	42%	0.417	S	S	*	.			trans	-58.6	82.4	161.1	61.1	0	0	0	0	106.3	N132 D136	N132-S134 PolarHBondContact O-N 2.82Å; S134-D136 PolarHBondContact O-N 3.06Å
135	H	57.8	Low	66.3	Low	64 Å²	64	76.6 Å²	76.6	30%	0.296	42%	0.424	S	S	.	.			trans	-54.7	113.3	170.3	-74.1	68	0	0	0	103.5	R61 F124 S133 L137	R61-H135 PolarHBondContact NH1-NE2 3.26Å; F124-H135 PolarHBondContact O-NE2 2.91Å; S133-H135 PolarHBondContact O-N 2.96Å; S133-H135 PolarHBondContact O-ND1 3.49Å; S133-H135 PolarHBondContact OG-CE1 2.88Å; S133-H135 VanDerWaalsContact OG-CE1 3.29Å; H135-L137 PolarHBondContact O-N 3.39Å
136	D	71.8	Confident	67.9	Low	68 Å²	68	76.6 Å²	76.6	36%	0.364	43%	0.43	S	S	.	.			trans	-67.3	85.4	177.8	-172.4	-21.4	0	0	0	106	S134 F138 K139 L140	S134-D136 PolarHBondContact O-N 3.06Å; D136-F138 PolarHBondContact O-N 3Å; D136-F138 WeakPolarHBondContact OD1-CB 3.36Å; D136-F138 PolarHBondContact OD1-N 2.99Å; D136-K139 HydrophobicContact CB-CB 3.98Å; D136-K139 HydrophobicContact CB-CD 3.84Å; D136-K139 HydrophobicContact CB-CG 3.97Å; D136-K139 VanDerWaalsContact CG-CG 3.46Å; D136-K139 WeakPolarHBondContact O-CA 3.3Å; D136-K139 WeakPolarHBondContact O-CB 3.26Å; D136-K139 PolarHBondContact O-N 2.71Å; D136-K139 PolarHBondContact OD1-N 3.17Å; D136-K139 VanDerWaalsContact OD1-N 3.11Å; D136-K139 VanDerWaalsContact OD2-CD 3.23Å; D136-K139 WeakPolarHBondContact OD2-CD 3.4Å; D136-K139 WeakPolarHBondContact OD2-CE 2.99Å; D136-K139 VanDerWaalsContact OD2-CG 3.27Å; D136-K139 WeakPolarHBondContact OD2-CG 3.34Å; D136-K139 IonicContact OD2-NZ 2.62Å; D136-K139 PolarHBondContact OD2-NZ 3.35Å; D136-L140 PolarHBondContact O-N 3.2Å
137	L	78.4	Confident	70	Confident	27 Å²	27	75.7 Å²	75.7	14%	0.141	42%	0.421	C	S	.	.	H	α-helix	trans	-59	-30.1	-175	178.2	71.6	0	0	0	109.9	Q67 A70 F71 H135 L140 T141	Q67-L137 HydrophobicContact CB-CD2 3.39Å; Q67-L137 HydrophobicContact CG-CD2 3.59Å; Q67-L137 WeakPolarHBondContact O-CD2 3.26Å; A70-L137 HydrophobicContact CB-CD2 3.82Å; A70-L137 HydrophobicContact CB-CG 4.49Å; F71-L137 HydrophobicContact CB-CD1 4.29Å; H135-L137 PolarHBondContact O-N 3.39Å; L137-L140 PolarHBondContact O-N 3.29Å; L137-T141 WeakPolarHBondContact O-CB 3.47Å; L137-T141 PolarHBondContact O-N 2.79Å; L137-T141 PolarHBondContact O-OG1 2.87Å
138	F	84.2	Confident	72.2	Confident	163 Å²	163	70.4 Å²	70.4	72%	0.715	39%	0.393	S	S	*	.	H	α-helix	trans	-64.1	-48.4	172.4	179.8	-95.9	0	0	0	110.8	D136 L140 T141 A142	D136-F138 PolarHBondContact O-N 3Å; D136-F138 WeakPolarHBondContact OD1-CB 3.36Å; D136-F138 PolarHBondContact OD1-N 2.99Å; F138-L140 PolarHBondContact O-N 3.25Å; F138-T141 PolarHBondContact O-N 3.43Å; F138-A142 WeakPolarHBondContact O-CB 3.31Å; F138-A142 PolarHBondContact O-N 3.29Å
139	K	86.4	Confident	74.6	Confident	127 Å²	127	66.7 Å²	66.7	55%	0.552	37%	0.374	S	S	*	.	H	α-helix	trans	-56.8	-47.6	172.1	-73.6	178.6	-174.2	121.2	0	112	D136 T141 A142 I143	D136-K139 HydrophobicContact CB-CB 3.98Å; D136-K139 HydrophobicContact CB-CD 3.84Å; D136-K139 HydrophobicContact CB-CG 3.97Å; D136-K139 VanDerWaalsContact CG-CG 3.46Å; D136-K139 WeakPolarHBondContact O-CA 3.3Å; D136-K139 WeakPolarHBondContact O-CB 3.26Å; D136-K139 PolarHBondContact O-N 2.71Å; D136-K139 PolarHBondContact OD1-N 3.17Å; D136-K139 VanDerWaalsContact OD1-N 3.11Å; D136-K139 VanDerWaalsContact OD2-CD 3.23Å; D136-K139 WeakPolarHBondContact OD2-CD 3.4Å; D136-K139 WeakPolarHBondContact OD2-CE 2.99Å; D136-K139 VanDerWaalsContact OD2-CG 3.27Å; D136-K139 WeakPolarHBondContact OD2-CG 3.34Å; D136-K139 IonicContact OD2-NZ 2.62Å; D136-K139 PolarHBondContact OD2-NZ 3.35Å; K139-T141 PolarHBondContact O-N 3.38Å; K139-A142 PolarHBondContact O-N 3.37Å; K139-I143 WeakPolarHBondContact O-CB 3.17Å; K139-I143 WeakPolarHBondContact O-CG1 3.39Å; K139-I143 PolarHBondContact O-N 3.23Å
140	L	84.5	Confident	77.2	Confident	15 Å²	15	64.7 Å²	64.7	8%	0.079	35%	0.347	C	S	.	.	H	α-helix	trans	-60.7	-45.4	179.3	-175.1	67.4	0	0	0	111.5	I54 L58 F71 F124 D136 L137 F138 I143 F144	I54-L140 HydrophobicContact CG2-CD2 4.18Å; L58-L140 HydrophobicContact CD1-CD2 4.22Å; L58-L140 HydrophobicContact CD2-CD2 4.46Å; F71-L140 HydrophobicContact CD2-CD2 4.26Å; F71-L140 HydrophobicContact CD2-CG 4.27Å; F71-L140 HydrophobicContact CE2-CD2 4.25Å; F71-L140 HydrophobicContact CE2-CG 4.02Å; F124-L140 HydrophobicContact CD1-CD1 4.2Å; F124-L140 HydrophobicContact CE1-CD1 4.42Å; D136-L140 PolarHBondContact O-N 3.2Å; L137-L140 PolarHBondContact O-N 3.29Å; F138-L140 PolarHBondContact O-N 3.25Å; L140-I143 PolarHBondContact O-N 3.46Å; L140-F144 HydrophobicContact CD1-CD2 3.8Å; L140-F144 HydrophobicContact CD1-CE2 3.65Å; L140-F144 HydrophobicContact CG-CD2 4.23Å; L140-F144 HydrophobicContact CG-CE2 4.48Å; L140-F144 WeakPolarHBondContact O-CD2 3.39Å; L140-F144 PolarHBondContact O-N 2.91Å
141	T	88.2	Confident	79.6	Confident	16 Å²	16	62.9 Å²	62.9	10%	0.098	33%	0.331	C	S	.	.	H	α-helix	trans	-63.5	-44.2	178.2	-57.2	0	0	0	0	111	A70 F73 L137 F138 K139 F144 F145	A70-T141 VanDerWaalsContact O-CG2 3.25Å; A70-T141 WeakPolarHBondContact O-CG2 3.5Å; F73-T141 HydrophobicContact CB-CG2 4.09Å; L137-T141 WeakPolarHBondContact O-CB 3.47Å; L137-T141 PolarHBondContact O-N 2.79Å; L137-T141 PolarHBondContact O-OG1 2.87Å; F138-T141 PolarHBondContact O-N 3.43Å; K139-T141 PolarHBondContact O-N 3.38Å; T141-F144 PolarHBondContact O-N 3.46Å; T141-F145 WeakPolarHBondContact O-CB 3.02Å; T141-F145 PolarHBondContact O-N 3.18Å
142	A	91	Very high	82.1	Confident	47 Å²	47	53.6 Å²	53.6	39%	0.388	29%	0.288	S	S	.	.	H	α-helix	trans	-63.9	-41.1	178.4	0	0	0	0	0	112.3	F138 K139 F145 A146	F138-A142 WeakPolarHBondContact O-CB 3.31Å; F138-A142 PolarHBondContact O-N 3.29Å; K139-A142 PolarHBondContact O-N 3.37Å; A142-F145 PolarHBondContact O-N 3.2Å; A142-A146 PolarHBondContact O-N 3.31Å
143	I	90.5	Very high	84.8	Confident	36 Å²	36	46.5 Å²	46.5	19%	0.185	25%	0.25	C	S	.	.	H	α-helix	trans	-58.8	-56.7	174.5	-75.8	171.5	0	0	0	109.5	F113 L117 F124 K139 L140 F145 A146 F147	F113-I143 HydrophobicContact CE1-CG2 4.1Å; F113-I143 HydrophobicContact CE2-CG2 3.92Å; F113-I143 WeakPolarHBondContact CE2-O 3.27Å; F113-I143 HydrophobicContact CZ-CB 4.26Å; F113-I143 HydrophobicContact CZ-CG2 3.24Å; F113-I143 WeakPolarHBondContact CZ-O 3.11Å; L117-I143 HydrophobicContact CD2-CG2 4.16Å; F124-I143 HydrophobicContact CE1-CD1 4.21Å; F124-I143 HydrophobicContact CZ-CD1 3.69Å; K139-I143 WeakPolarHBondContact O-CB 3.17Å; K139-I143 WeakPolarHBondContact O-CG1 3.39Å; K139-I143 PolarHBondContact O-N 3.23Å; L140-I143 PolarHBondContact O-N 3.46Å; I143-F145 VanDerWaalsContact C-N 3.31Å; I143-F145 PolarHBondContact O-N 3.31Å; I143-A146 PolarHBondContact O-N 2.93Å; I143-F147 PolarHBondContact O-N 3.04Å
144	F	91.7	Very high	87.1	Confident	9 Å²	9	44.1 Å²	44.1	4%	0.039	23%	0.234	C	C	.	.	H	α-helix	trans	-68.6	-27.5	-179.9	-84.1	-91.7	0	0	0	113.5	T51 I54 F71 A74 L117 L140 T141 F147 N148	T51-F144 HydrophobicContact CG2-CD1 4.08Å; I54-F144 HydrophobicContact CD1-CE1 4.12Å; I54-F144 HydrophobicContact CD1-CE2 4.2Å; I54-F144 HydrophobicContact CD1-CZ 3.58Å; I54-F144 HydrophobicContact CG1-CD1 4.28Å; I54-F144 HydrophobicContact CG1-CE1 3.61Å; I54-F144 HydrophobicContact CG1-CE2 4.01Å; I54-F144 HydrophobicContact CG1-CZ 3.47Å; I54-F144 VanDerWaalsContact CG1-CZ 3.47Å; F71-F144 HydrophobicContact CE2-CB 3.85Å; F71-F144 AromaticContact CE2-CD2 3.91Å; F71-F144 HydrophobicContact CE2-CD2 3.91Å; F71-F144 AromaticContact CE2-CG 3.9Å; F71-F144 HydrophobicContact CE2-CG 3.9Å; F71-F144 HydrophobicContact CZ-CB 3.94Å; F71-F144 HydrophobicContact CZ-CD1 4.19Å; F71-F144 HydrophobicContact CZ-CD2 4.16Å; F71-F144 AromaticContact CZ-CG 3.82Å; F71-F144 HydrophobicContact CZ-CG 3.82Å; A74-F144 HydrophobicContact CB-CB 3.73Å; L117-F144 HydrophobicContact CD1-CZ 4.13Å; L140-F144 HydrophobicContact CD1-CD2 3.8Å; L140-F144 HydrophobicContact CD1-CE2 3.65Å; L140-F144 HydrophobicContact CG-CD2 4.23Å; L140-F144 HydrophobicContact CG-CE2 4.48Å; L140-F144 WeakPolarHBondContact O-CD2 3.39Å; L140-F144 PolarHBondContact O-N 2.91Å; T141-F144 PolarHBondContact O-N 3.46Å; F144-F147 HydrophobicContact CD1-CD1 4.16Å; F144-F147 HydrophobicContact CE1-CD1 4.35Å; F144-F147 WeakPolarHBondContact O-CB 3.43Å; F144-F147 PolarHBondContact O-N 3.03Å; F144-N148 WeakPolarHBondContact O-CB 3.37Å; F144-N148 PolarHBondContact O-N 3.1Å; F144-N148 PolarHBondContact O-ND2 3.39Å
145	F	94	Very high	89.3	Confident	85 Å²	85	39.1 Å²	39.1	37%	0.373	20%	0.198	S	C	.	.	H	α-helix	trans	-61.6	-47.9	170.3	-179.6	-84.9	0	0	0	110.7	F73 W76 P77 T141 A142 I143 F147 N148 F149	F73-F145 WeakPolarHBondContact O-CD2 3.4Å; W76-F145 HydrophobicContact CB-CE2 4.38Å; P77-F145 HydrophobicContact CG-CD1 4.43Å; P77-F145 HydrophobicContact CG-CD2 3.82Å; P77-F145 HydrophobicContact CG-CE1 4.32Å; P77-F145 HydrophobicContact CG-CE2 3.71Å; P77-F145 HydrophobicContact CG-CG 4.19Å; P77-F145 HydrophobicContact CG-CZ 3.97Å; T141-F145 WeakPolarHBondContact O-CB 3.02Å; T141-F145 PolarHBondContact O-N 3.18Å; A142-F145 PolarHBondContact O-N 3.2Å; I143-F145 VanDerWaalsContact C-N 3.31Å; I143-F145 PolarHBondContact O-N 3.31Å; F145-F147 VanDerWaalsContact C-N 3.31Å; F145-F147 PolarHBondContact O-N 3.09Å; F145-N148 PolarHBondContact O-N 3.5Å; F145-F149 WeakPolarHBondContact O-CB 3.29Å; F145-F149 PolarHBondContact O-N 3.22Å
146	A	95.2	Very high	91.1	Very high	44 Å²	44	36 Å²	36	36%	0.364	18%	0.184	S	C	.	.	H	α-helix	trans	-62	-40.4	176.2	0	0	0	0	0	111.6	A142 I143 F149 L150	A142-A146 PolarHBondContact O-N 3.31Å; I143-A146 PolarHBondContact O-N 2.93Å; A146-F149 WeakPolarHBondContact O-CB 3.37Å; A146-F149 PolarHBondContact O-N 3.08Å; A146-L150 WeakPolarHBondContact O-CG 3.46Å; A146-L150 PolarHBondContact O-N 3.35Å; A146-L150 VanDerWaalsContact O-N 3.07Å
147	F	94	Very high	92.2	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-59.7	-47.5	175.5	-168.3	-136.1	0	0	0	113	P47 L50 I110 F113 M114 I143 F144 F145 F149 L150 A151	P47-F147 VanDerWaalsContact CA-CE1 3.42Å; P47-F147 HydrophobicContact CB-CD1 4.14Å; P47-F147 HydrophobicContact CB-CE1 3.53Å; P47-F147 HydrophobicContact CB-CE2 4.12Å; P47-F147 HydrophobicContact CB-CZ 3.51Å; P47-F147 HydrophobicContact CG-CE1 4.32Å; P47-F147 HydrophobicContact CG-CE2 4.2Å; P47-F147 HydrophobicContact CG-CZ 3.8Å; L50-F147 HydrophobicContact CB-CE1 4.32Å; L50-F147 HydrophobicContact CD1-CE1 4.36Å; L50-F147 HydrophobicContact CD1-CZ 4.25Å; I110-F147 HydrophobicContact CG2-CE2 3.86Å; F113-F147 HydrophobicContact CB-CD2 4.07Å; F113-F147 HydrophobicContact CB-CE2 4.32Å; F113-F147 HydrophobicContact CD1-CB 4Å; F113-F147 HydrophobicContact CD1-CD1 4.42Å; F113-F147 AromaticContact CD1-CD2 3.15Å; F113-F147 HydrophobicContact CD1-CD2 3.15Å; F113-F147 AromaticContact CD1-CE2 3.58Å; F113-F147 HydrophobicContact CD1-CE2 3.58Å; F113-F147 AromaticContact CD1-CG 3.64Å; F113-F147 HydrophobicContact CD1-CG 3.64Å; F113-F147 HydrophobicContact CD1-CZ 4.37Å; F113-F147 HydrophobicContact CD2-CD2 4.4Å; F113-F147 HydrophobicContact CE1-CB 3.49Å; F113-F147 VanDerWaalsContact CE1-CB 3.49Å; F113-F147 HydrophobicContact CE1-CD1 4.1Å; F113-F147 AromaticContact CE1-CD2 3.53Å; F113-F147 HydrophobicContact CE1-CD2 3.53Å; F113-F147 HydrophobicContact CE1-CE2 4.2Å; F113-F147 AromaticContact CE1-CG 3.46Å; F113-F147 HydrophobicContact CE1-CG 3.46Å; F113-F147 VanDerWaalsContact CE1-CG 3.46Å; F113-F147 HydrophobicContact CE2-CB 4.07Å; F113-F147 HydrophobicContact CG-CB 4.46Å; F113-F147 AromaticContact CG-CD2 3.63Å; F113-F147 HydrophobicContact CG-CD2 3.63Å; F113-F147 HydrophobicContact CG-CE2 4.21Å; F113-F147 HydrophobicContact CG-CG 4.33Å; F113-F147 HydrophobicContact CZ-CB 3.52Å; F113-F147 HydrophobicContact CZ-CD2 4.29Å; F113-F147 HydrophobicContact CZ-CG 4.04Å; M114-F147 HydrophobicContact CE-CE2 4.18Å; M114-F147 HydrophobicContact CE-CZ 3.71Å; M114-F147 HydrophobicContact CG-CE2 4.13Å; M114-F147 HydrophobicContact CG-CZ 4.12Å; I143-F147 PolarHBondContact O-N 3.04Å; F144-F147 HydrophobicContact CD1-CD1 4.16Å; F144-F147 HydrophobicContact CE1-CD1 4.35Å; F144-F147 WeakPolarHBondContact O-CB 3.43Å; F144-F147 PolarHBondContact O-N 3.03Å; F145-F147 VanDerWaalsContact C-N 3.31Å; F145-F147 PolarHBondContact O-N 3.09Å; F147-F149 VanDerWaalsContact C-N 3.33Å; F147-L150 PolarHBondContact O-N 2.98Å; F147-A151 PolarHBondContact O-N 3.2Å
148	N	94.7	Very high	93	Very high	2 Å²	2	31.6 Å²	31.6	1%	0.011	16%	0.161	C	C	.	.	H	α-helix	trans	-70.4	-31	178.1	-80.6	-88.7	0	0	0	112	T51 A74 P77 F78 F144 F145 L150 A151 A152	T51-N148 WeakPolarHBondContact CG2-ND2 3.37Å; T51-N148 PolarHBondContact OG1-ND2 3.33Å; A74-N148 WeakPolarHBondContact O-CB 3.48Å; A74-N148 VanDerWaalsContact O-CG 3.27Å; A74-N148 PolarHBondContact O-ND2 3.05Å; P77-N148 HydrophobicContact CB-CB 4.33Å; P77-N148 HydrophobicContact CG-CB 4.06Å; F78-N148 HydrophobicContact CD2-CB 4.28Å; F78-N148 HydrophobicContact CE2-CB 4.3Å; F144-N148 WeakPolarHBondContact O-CB 3.37Å; F144-N148 PolarHBondContact O-N 3.1Å; F144-N148 PolarHBondContact O-ND2 3.39Å; F145-N148 PolarHBondContact O-N 3.5Å; N148-L150 VanDerWaalsContact C-N 3.33Å; N148-A151 PolarHBondContact O-N 2.93Å; N148-A152 WeakPolarHBondContact O-CB 3.22Å; N148-A152 PolarHBondContact O-N 3.16Å
149	F	96.4	Very high	93.4	Very high	79 Å²	79	24 Å²	24	35%	0.346	13%	0.127	S	C	.	.	H	α-helix	trans	-61.9	-42.6	172.9	178.6	-94.1	0	0	0	111.8	P77 W84 F145 A146 F147 T153	P77-F149 HydrophobicContact CB-CB 4.02Å; P77-F149 HydrophobicContact CB-CD2 4.43Å; P77-F149 HydrophobicContact CG-CB 4.07Å; W84-F149 AromaticContact CD2-CE2 3.68Å; W84-F149 HydrophobicContact CD2-CE2 3.68Å; W84-F149 HydrophobicContact CD2-CZ 4.33Å; W84-F149 AromaticContact CE2-CE2 3.49Å; W84-F149 VanDerWaalsContact CE2-CE2 3.49Å; W84-F149 AromaticContact CE3-CE2 3.93Å; W84-F149 HydrophobicContact CE3-CE2 3.93Å; W84-F149 HydrophobicContact CG-CE2 4.24Å; W84-F149 HydrophobicContact CG-CZ 4.46Å; W84-F149 AromaticContact CH2-CD2 3.69Å; W84-F149 HydrophobicContact CH2-CD2 3.69Å; W84-F149 AromaticContact CH2-CE2 3.82Å; W84-F149 HydrophobicContact CH2-CE2 3.82Å; W84-F149 AromaticContact CZ2-CD2 3.6Å; W84-F149 HydrophobicContact CZ2-CD2 3.6Å; W84-F149 AromaticContact CZ2-CE2 3.59Å; W84-F149 HydrophobicContact CZ2-CE2 3.59Å; W84-F149 HydrophobicContact CZ3-CD2 4.21Å; W84-F149 AromaticContact CZ3-CE2 3.99Å; W84-F149 HydrophobicContact CZ3-CE2 3.99Å; W84-F149 AromaticContact NE1-CE2 3.93Å; F145-F149 WeakPolarHBondContact O-CB 3.29Å; F145-F149 PolarHBondContact O-N 3.22Å; A146-F149 WeakPolarHBondContact O-CB 3.37Å; A146-F149 PolarHBondContact O-N 3.08Å; F147-F149 VanDerWaalsContact C-N 3.33Å; F149-T153 WeakPolarHBondContact O-CB 3.33Å; F149-T153 PolarHBondContact O-N 3.48Å; F149-T153 PolarHBondContact O-OG1 3.28Å
150	L	97.1	Very high	93.7	Very high	28 Å²	28	17.9 Å²	17.9	15%	0.147	10%	0.101	C	C	.	.	H	α-helix	trans	-63.8	-48.8	172.8	-64.1	170.6	0	0	0	111.1	T106 L109 I110 A146 F147 N148 A152 T153 Q154	T106-L150 HydrophobicContact CG2-CB 3.99Å; T106-L150 HydrophobicContact CG2-CD2 4.25Å; T106-L150 WeakPolarHBondContact CG2-O 3.41Å; L109-L150 HydrophobicContact CB-CD1 3.71Å; L109-L150 HydrophobicContact CB-CD2 3.98Å; L109-L150 HydrophobicContact CB-CG 4.49Å; L109-L150 HydrophobicContact CD1-CD2 3.84Å; I110-L150 HydrophobicContact CD1-CB 4.11Å; I110-L150 HydrophobicContact CG1-CB 3.62Å; I110-L150 HydrophobicContact CG1-CD1 4.26Å; A146-L150 WeakPolarHBondContact O-CG 3.46Å; A146-L150 PolarHBondContact O-N 3.35Å; A146-L150 VanDerWaalsContact O-N 3.07Å; F147-L150 PolarHBondContact O-N 2.98Å; N148-L150 VanDerWaalsContact C-N 3.33Å; L150-A152 VanDerWaalsContact C-N 3.32Å; L150-A152 PolarHBondContact O-N 2.93Å; L150-T153 WeakPolarHBondContact O-CB 3.4Å; L150-T153 PolarHBondContact O-N 3.25Å; L150-T153 VanDerWaalsContact O-N 3.1Å; L150-Q154 PolarHBondContact O-N 3.08Å
151	A	96.1	Very high	94.1	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-61.7	-37.7	179.2	0	0	0	0	0	112.8	P47 F78 F147 N148 Q154 D155	P47-A151 HydrophobicContact CB-CB 3.7Å; P47-A151 HydrophobicContact CG-CB 4.13Å; F78-A151 HydrophobicContact CE2-CB 3.8Å; F78-A151 HydrophobicContact CZ-CB 3.72Å; F147-A151 PolarHBondContact O-N 3.2Å; N148-A151 PolarHBondContact O-N 2.93Å; A151-Q154 WeakPolarHBondContact O-CB 3.5Å; A151-Q154 PolarHBondContact O-N 2.62Å; A151-D155 WeakPolarHBondContact O-CB 3.22Å; A151-D155 PolarHBondContact O-N 3.38Å
152	A	95.3	Very high	94.3	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-69.7	-33	174.8	0	0	0	0	0	112.3	P77 F78 K81 W84 N148 L150 D155 I156	P77-A152 HydrophobicContact CB-CB 4.26Å; F78-A152 HydrophobicContact CD1-CB 4.14Å; F78-A152 HydrophobicContact CD2-CB 3.98Å; F78-A152 HydrophobicContact CE1-CB 4.2Å; F78-A152 HydrophobicContact CE2-CB 4.04Å; F78-A152 HydrophobicContact CG-CB 4.04Å; F78-A152 HydrophobicContact CZ-CB 4.15Å; K81-A152 HydrophobicContact CB-CB 4.33Å; W84-A152 HydrophobicContact CZ2-CB 3.98Å; N148-A152 WeakPolarHBondContact O-CB 3.22Å; N148-A152 PolarHBondContact O-N 3.16Å; L150-A152 VanDerWaalsContact C-N 3.32Å; L150-A152 PolarHBondContact O-N 2.93Å; A152-D155 WeakPolarHBondContact O-CB 3.36Å; A152-D155 PolarHBondContact O-N 3.1Å; A152-I156 WeakPolarHBondContact O-CG1 3.41Å; A152-I156 PolarHBondContact O-N 3.19Å; A152-I156 VanDerWaalsContact O-N 3.16Å
153	T	96.6	Very high	94.3	Very high	4 Å²	4	15.2 Å²	15.2	3%	0.025	8%	0.079	C	C	.	.	H	α-helix	trans	-68.6	-42	172.7	-58.7	0	0	0	0	110.9	W84 V88 W102 F149 L150 D155 I156 V157	W84-T153 PolarHBondContact NE1-OG1 3.07Å; V88-T153 HydrophobicContact CG2-CG2 4.08Å; W102-T153 HydrophobicContact CE3-CG2 4.01Å; F149-T153 WeakPolarHBondContact O-CB 3.33Å; F149-T153 PolarHBondContact O-N 3.48Å; F149-T153 PolarHBondContact O-OG1 3.28Å; L150-T153 WeakPolarHBondContact O-CB 3.4Å; L150-T153 PolarHBondContact O-N 3.25Å; L150-T153 VanDerWaalsContact O-N 3.1Å; T153-D155 VanDerWaalsContact C-N 3.31Å; T153-D155 PolarHBondContact O-N 2.9Å; T153-I156 PolarHBondContact O-N 2.74Å; T153-V157 VanDerWaalsContact O-CG2 3.29Å; T153-V157 WeakPolarHBondContact O-CG2 3.5Å; T153-V157 PolarHBondContact O-N 2.89Å
154	Q	95.8	Very high	94.2	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-58.1	-45.6	172.8	-175.5	-173.6	19.2	0	0	111	L103 T106 Q107 I110 L150 A151 I156 V157 V158	L103-Q154 HydrophobicContact CD1-CG 3.91Å; T106-Q154 HydrophobicContact CG2-CB 4.03Å; Q107-Q154 HydrophobicContact CG-CG 4.45Å; I110-Q154 HydrophobicContact CD1-CB 4.36Å; L150-Q154 PolarHBondContact O-N 3.08Å; A151-Q154 WeakPolarHBondContact O-CB 3.5Å; A151-Q154 PolarHBondContact O-N 2.62Å; Q154-I156 PolarHBondContact O-N 3.13Å; Q154-V157 PolarHBondContact O-N 2.7Å; Q154-V157 VanDerWaalsContact O-N 3.1Å; Q154-V158 HydrophobicContact CG-CG2 4Å; Q154-V158 VanDerWaalsContact O-CG2 3.32Å; Q154-V158 WeakPolarHBondContact O-CG2 3.27Å; Q154-V158 PolarHBondContact O-N 3.32Å
155	D	95.4	Very high	94	Very high	7 Å²	7	16.8 Å²	16.8	4%	0.037	9%	0.09	C	C	.	.	H	α-helix	trans	-55.1	-50.3	177.4	-175.8	51.1	0	0	0	112.3	Q44 F78 K81 A151 A152 T153 V157 V158 D159	Q44-D155 VanDerWaalsContact CD-CB 3.46Å; Q44-D155 VanDerWaalsContact CD-OD1 3.28Å; Q44-D155 HydrophobicContact CG-CB 4.28Å; Q44-D155 VanDerWaalsContact NE2-CB 3.26Å; Q44-D155 PolarHBondContact NE2-OD1 3.12Å; Q44-D155 PolarHBondContact OE1-OD1 2.8Å; F78-D155 HydrophobicContact CE1-CB 4.13Å; K81-D155 IonicContact NZ-OD2 3.93Å; K81-D155 PolarHBondContact NZ-OD2 2.86Å; A151-D155 WeakPolarHBondContact O-CB 3.22Å; A151-D155 PolarHBondContact O-N 3.38Å; A152-D155 WeakPolarHBondContact O-CB 3.36Å; A152-D155 PolarHBondContact O-N 3.1Å; T153-D155 VanDerWaalsContact C-N 3.31Å; T153-D155 PolarHBondContact O-N 2.9Å; D155-V157 PolarHBondContact O-N 3.29Å; D155-V158 PolarHBondContact O-N 3.33Å; D155-D159 VanDerWaalsContact O-CB 3.27Å; D155-D159 WeakPolarHBondContact O-CB 3.35Å; D155-D159 PolarHBondContact O-N 3.44Å
156	I	94.8	Very high	93.8	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-53.9	-45	175.4	-65	159.4	0	0	0	110.9	K81 A85 V88 A152 T153 Q154 C160	K81-I156 HydrophobicContact CB-CD1 3.83Å; K81-I156 HydrophobicContact CB-CG1 4.2Å; K81-I156 HydrophobicContact CD-CG1 3.96Å; A85-I156 HydrophobicContact CB-CD1 3.89Å; A85-I156 HydrophobicContact CB-CG1 4.18Å; A85-I156 HydrophobicContact CB-CG2 3.97Å; V88-I156 HydrophobicContact CB-CG2 4.23Å; V88-I156 HydrophobicContact CG1-CG2 3.98Å; V88-I156 HydrophobicContact CG2-CD1 4.49Å; A152-I156 WeakPolarHBondContact O-CG1 3.41Å; A152-I156 PolarHBondContact O-N 3.19Å; A152-I156 VanDerWaalsContact O-N 3.16Å; T153-I156 PolarHBondContact O-N 2.74Å; Q154-I156 PolarHBondContact O-N 3.13Å; I156-C160 VanDerWaalsContact O-CB 3.29Å; I156-C160 WeakPolarHBondContact O-CB 3.19Å; I156-C160 PolarHBondContact O-N 3.12Å; I156-C160 VanDerWaalsContact O-N 3.13Å
157	V	94.9	Very high	93.5	Very high	2 Å²	2	12 Å²	12	1%	0.012	6%	0.064	C	C	.	.	H	α-helix	trans	-70.5	-44.7	-175.7	178.7	0	0	0	0	111.4	V88 R99 W102 L103 T153 Q154 D155 C160 W161	V88-V157 HydrophobicContact CG1-CG2 3.57Å; R99-V157 HydrophobicContact CB-CG1 4.13Å; R99-V157 WeakPolarHBondContact O-CG1 3.3Å; W102-V157 HydrophobicContact CB-CG2 3.48Å; W102-V157 VanDerWaalsContact CB-CG2 3.48Å; W102-V157 HydrophobicContact CG-CG2 4.36Å; L103-V157 HydrophobicContact CB-CG1 3.87Å; T153-V157 VanDerWaalsContact O-CG2 3.29Å; T153-V157 WeakPolarHBondContact O-CG2 3.5Å; T153-V157 PolarHBondContact O-N 2.89Å; Q154-V157 PolarHBondContact O-N 2.7Å; Q154-V157 VanDerWaalsContact O-N 3.1Å; D155-V157 PolarHBondContact O-N 3.29Å; V157-C160 PolarHBondContact O-N 3.38Å; V157-W161 VanDerWaalsContact O-CB 3.3Å; V157-W161 WeakPolarHBondContact O-CB 3.34Å; V157-W161 PolarHBondContact O-N 2.91Å
158	V	95.3	Very high	93.1	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-70.7	-43.1	-178	-178.8	0	0	0	0	110.8	L37 L40 Y41 L103 Q154 D155 C160 W161 A162	L37-V158 HydrophobicContact CD2-CG1 4.2Å; L40-V158 HydrophobicContact CB-CG1 3.9Å; L40-V158 HydrophobicContact CB-CG2 4.09Å; L40-V158 HydrophobicContact CD1-CG1 4.48Å; L40-V158 HydrophobicContact CD1-CG2 4.47Å; Y41-V158 HydrophobicContact CD1-CB 4.43Å; Y41-V158 HydrophobicContact CD1-CG1 3.75Å; Y41-V158 HydrophobicContact CD2-CG1 4.24Å; Y41-V158 HydrophobicContact CE1-CB 4.03Å; Y41-V158 HydrophobicContact CE1-CG1 3.45Å; Y41-V158 VanDerWaalsContact CE1-CG1 3.45Å; Y41-V158 HydrophobicContact CE2-CG1 3.99Å; Y41-V158 HydrophobicContact CG-CG1 4.13Å; L103-V158 HydrophobicContact CD1-CG2 3.83Å; Q154-V158 HydrophobicContact CG-CG2 4Å; Q154-V158 VanDerWaalsContact O-CG2 3.32Å; Q154-V158 WeakPolarHBondContact O-CG2 3.27Å; Q154-V158 PolarHBondContact O-N 3.32Å; D155-V158 PolarHBondContact O-N 3.33Å; V158-C160 PolarHBondContact O-N 2.86Å; V158-W161 PolarHBondContact O-N 3.42Å; V158-W161 VanDerWaalsContact O-N 3.12Å; V158-A162 WeakPolarHBondContact O-CB 3.47Å; V158-A162 PolarHBondContact O-N 3.05Å
159	D	94	Very high	92.6	Very high	2 Å²	2	17.3 Å²	17.3	1%	0.011	9%	0.094	C	C	.	.	H	α-helix	trans	-53.6	-46.5	172.2	-85.8	-7.1	0	0	0	110.3	Y41 K81 D155 A162 N178 M417	Y41-D159 WeakPolarHBondContact CE1-OD1 3.43Å; Y41-D159 WeakPolarHBondContact OH-CA 3.4Å; Y41-D159 PolarHBondContact OH-OD1 3.13Å; K81-D159 IonicContact NZ-OD2 4Å; D155-D159 VanDerWaalsContact O-CB 3.27Å; D155-D159 WeakPolarHBondContact O-CB 3.35Å; D155-D159 PolarHBondContact O-N 3.44Å; D159-A162 PolarHBondContact O-N 3.34Å; D159-N178 PolarHBondContact OD1-ND2 3.11Å; D159-N178 VanDerWaalsContact OD1-ND2 3.12Å; D159-M417 HydrophobicContact CB-CB 4.42Å
160	C	91.5	Very high	92.3	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-71.4	-36.6	179.7	-160.6	0	0	0	0	113.2	R99 I156 V157 V158 A162 L163 G413 G414	R99-C160 PolarHBondContact NH1-SG 3.46Å; R99-C160 PolarHBondContact NH2-SG 3.33Å; I156-C160 VanDerWaalsContact O-CB 3.29Å; I156-C160 WeakPolarHBondContact O-CB 3.19Å; I156-C160 PolarHBondContact O-N 3.12Å; I156-C160 VanDerWaalsContact O-N 3.13Å; V157-C160 PolarHBondContact O-N 3.38Å; V158-C160 PolarHBondContact O-N 2.86Å; C160-A162 VanDerWaalsContact C-N 3.27Å; C160-A162 PolarHBondContact O-N 2.99Å; C160-L163 WeakPolarHBondContact O-CB 3.43Å; C160-L163 PolarHBondContact O-N 3.02Å; C160-G413 WeakPolarHBondContact SG-CA 3.31Å; C160-G414 PolarHBondContact SG-N 3.33Å
161	W	92.8	Very high	92	Very high	7 Å²	7	13.4 Å²	13.4	3%	0.027	8%	0.077	C	C	.	.	H	α-helix	trans	-67.6	-33.6	179.6	-160	11.4	0	0	0	111	L40 R99 L103 V157 V158 L163 T164 M165 V243 K247 E249	L40-W161 HydrophobicContact CD1-CE3 3.89Å; L40-W161 HydrophobicContact CD1-CZ3 3.8Å; R99-W161 HydrophobicContact CB-CB 4.27Å; R99-W161 HydrophobicContact CB-CD2 3.95Å; R99-W161 HydrophobicContact CB-CG 3.88Å; R99-W161 HydrophobicContact CG-CB 4Å; R99-W161 HydrophobicContact CG-CD2 4.36Å; R99-W161 HydrophobicContact CG-CG 3.77Å; L103-W161 HydrophobicContact CD2-CE3 3.73Å; L103-W161 HydrophobicContact CD2-CH2 4.19Å; L103-W161 HydrophobicContact CD2-CZ3 3.25Å; V157-W161 VanDerWaalsContact O-CB 3.3Å; V157-W161 WeakPolarHBondContact O-CB 3.34Å; V157-W161 PolarHBondContact O-N 2.91Å; V158-W161 PolarHBondContact O-N 3.42Å; V158-W161 VanDerWaalsContact O-N 3.12Å; W161-L163 PolarHBondContact O-N 3.45Å; W161-T164 PolarHBondContact O-N 2.74Å; W161-T164 PolarHBondContact O-OG1 3.21Å; W161-T164 VanDerWaalsContact O-OG1 3.11Å; W161-M165 HydrophobicContact CB-CE 4.49Å; W161-M165 HydrophobicContact CD2-CE 3.2Å; W161-M165 VanDerWaalsContact CE2-CE 3.43Å; W161-M165 HydrophobicContact CE3-CE 3.39Å; W161-M165 HydrophobicContact CG-CE 3.67Å; W161-M165 HydrophobicContact CH2-CE 4.07Å; W161-M165 HydrophobicContact CZ2-CE 3.91Å; W161-M165 HydrophobicContact CZ3-CE 3.79Å; W161-M165 WeakPolarHBondContact O-CB 3.49Å; W161-M165 PolarHBondContact O-N 3.4Å; W161-V243 HydrophobicContact CH2-CG1 3.73Å; W161-V243 HydrophobicContact CZ3-CG1 4.03Å; W161-K247 HydrophobicContact CH2-CB 4.29Å; W161-K247 HydrophobicContact CH2-CG 3.53Å; W161-K247 HydrophobicContact CZ2-CD 4.37Å; W161-K247 HydrophobicContact CZ2-CG 3.45Å; W161-K247 VanDerWaalsContact CZ2-CG 3.45Å; W161-E249 HydrophobicContact CZ2-CG 4.22Å
162	A	92.9	Very high	91.6	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-56.9	-33.9	175.3	0	0	0	0	0	112.8	L37 V158 D159 C160 T164 L166 A174	L37-A162 HydrophobicContact CD1-CB 3.91Å; L37-A162 HydrophobicContact CD2-CB 3.88Å; V158-A162 WeakPolarHBondContact O-CB 3.47Å; V158-A162 PolarHBondContact O-N 3.05Å; D159-A162 PolarHBondContact O-N 3.34Å; C160-A162 VanDerWaalsContact C-N 3.27Å; C160-A162 PolarHBondContact O-N 2.99Å; A162-T164 VanDerWaalsContact C-N 3.26Å; A162-T164 PolarHBondContact O-N 3.12Å; A162-L166 PolarHBondContact O-N 3.09Å; A162-A174 HydrophobicContact CB-CB 3.78Å
163	L	90.6	Very high	91.5	Very high	15 Å²	15	16 Å²	16	8%	0.079	9%	0.088	C	C	.	.	H	α-helix	trans	-66.1	-26.4	177.8	-54	-174.2	0	0	0	113.7	C160 W161 V171 A405 M417	C160-L163 WeakPolarHBondContact O-CB 3.43Å; C160-L163 PolarHBondContact O-N 3.02Å; W161-L163 PolarHBondContact O-N 3.45Å; L163-V171 HydrophobicContact CD2-CG2 4Å; L163-A405 HydrophobicContact CD2-CB 3.82Å; L163-A405 WeakPolarHBondContact CD2-O 3.36Å; L163-M417 HydrophobicContact CD1-CG 4.03Å; L163-M417 HydrophobicContact CD2-CG 4.49Å; L163-M417 HydrophobicContact CD2-SD 4.34Å
164	T	88.9	Confident	91.4	Very high	67 Å²	67	16 Å²	16	41%	0.411	9%	0.088	S	C	.	.	H	α-helix	trans	-110.7	-18.4	-177.7	56.2	0	0	0	0	113.4	W161 A162 P410	W161-T164 PolarHBondContact O-N 2.74Å; W161-T164 PolarHBondContact O-OG1 3.21Å; W161-T164 VanDerWaalsContact O-OG1 3.11Å; A162-T164 VanDerWaalsContact C-N 3.26Å; A162-T164 PolarHBondContact O-N 3.12Å; T164-P410 HydrophobicContact CG2-CB 4.08Å
165	M	88.5	Confident	91.3	Very high	10 Å²	10	16.1 Å²	16.1	5%	0.049	9%	0.089	C	C	.	.	H	α-helix	trans	-83.7	-32.5	-178.2	-163.4	-167.6	-63.2	0	0	111.9	N33 L36 L37 W161	N33-M165 HydrophobicContact CB-CG 3.78Å; N33-M165 HydrophobicContact CB-SD 3.9Å; N33-M165 PolarHBondContact ND2-O 3.5Å; L36-M165 HydrophobicContact CD2-CE 4.05Å; L36-M165 HydrophobicContact CD2-SD 4.06Å; L36-M165 HydrophobicContact CG-SD 4.46Å; L37-M165 HydrophobicContact CD1-SD 4.27Å; L37-M165 HydrophobicContact CD2-CE 3.84Å; L37-M165 HydrophobicContact CD2-SD 4.01Å; L37-M165 HydrophobicContact CG-CE 4.23Å; L37-M165 HydrophobicContact CG-SD 3.73Å; W161-M165 HydrophobicContact CB-CE 4.49Å; W161-M165 HydrophobicContact CD2-CE 3.2Å; W161-M165 VanDerWaalsContact CE2-CE 3.43Å; W161-M165 HydrophobicContact CE3-CE 3.39Å; W161-M165 HydrophobicContact CG-CE 3.67Å; W161-M165 HydrophobicContact CH2-CE 4.07Å; W161-M165 HydrophobicContact CZ2-CE 3.91Å; W161-M165 HydrophobicContact CZ3-CE 3.79Å; W161-M165 WeakPolarHBondContact O-CB 3.49Å; W161-M165 PolarHBondContact O-N 3.4Å
166	L	90	Very high	91.2	Very high	7 Å²	7	16.2 Å²	16.2	4%	0.037	9%	0.09	C	C	.	.	S	Bend	trans	-90.2	150.4	174.5	-63.1	175.8	0	0	0	110.3	D30 N33 L37 A162 A174	D30-L166 HydrophobicContact CB-CD2 4.28Å; N33-L166 HydrophobicContact CB-CD2 4.33Å; L37-L166 HydrophobicContact CD1-CD1 3.8Å; L37-L166 HydrophobicContact CD1-CD2 3.9Å; L37-L166 HydrophobicContact CD1-CG 3.62Å; A162-L166 PolarHBondContact O-N 3.09Å; L166-A174 HydrophobicContact CD1-CB 4.05Å
167	S	88	Confident	91.3	Very high	21 Å²	21	16.4 Å²	16.4	15%	0.147	9%	0.091	C	C	.	.			trans	-60.6	149.5	171.7	-58.9	0	0	0	0	110.7	D30 E169 N170 V171	D30-S167 PolarHBondContact OD1-N 3.02Å; D30-S167 PolarHBondContact OD1-OG 3.42Å; D30-S167 WeakPolarHBondContact OD2-CB 3.4Å; D30-S167 PolarHBondContact OD2-N 2.78Å; D30-S167 PolarHBondContact OD2-OG 3.16Å; S167-E169 PolarHBondContact O-N 3.38Å; S167-N170 CarbonylContact O-C 3.32Å; S167-N170 WeakPolarHBondContact O-CA 3.49Å; S167-N170 PolarHBondContact O-N 2.97Å; S167-V171 PolarHBondContact O-N 3.26Å
168	P	84.7	Confident	91.3	Very high	64 Å²	64	16.6 Å²	16.6	42%	0.416	9%	0.092	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-27.9	179.7	-27.1	35.5	0	0	0	114.5
169	E	84.5	Confident	91.2	Very high	50 Å²	50	16.7 Å²	16.7	23%	0.234	9%	0.093	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.4	-31.3	173.8	-62.8	80.1	-169.4	0	0	113.1	R22 T25 S167	R22-E169 HydrophobicContact CG-CG 4.03Å; T25-E169 PolarHBondContact OG1-OE2 3.48Å; S167-E169 PolarHBondContact O-N 3.38Å
170	N	89.7	Confident	91.3	Very high	17 Å²	17	17.2 Å²	17.2	9%	0.091	10%	0.096	C	C	.	.	T	Hydrogen-bonded Turn	trans	-103.8	-1.8	-173.5	-66.2	-35.8	0	0	0	113.1	D30 S167 G172 Y173	D30-N170 WeakPolarHBondContact OD2-CB 3.4Å; D30-N170 PolarHBondContact OD2-ND2 3.14Å; S167-N170 CarbonylContact O-C 3.32Å; S167-N170 WeakPolarHBondContact O-CA 3.49Å; S167-N170 PolarHBondContact O-N 2.97Å; N170-G172 PolarHBondContact O-N 3.38Å; N170-Y173 HydrophobicContact CB-CD2 4.04Å; N170-Y173 WeakPolarHBondContact O-CB 3.47Å; N170-Y173 WeakPolarHBondContact O-CD2 3.06Å; N170-Y173 PolarHBondContact O-N 3.29Å
171	V	90.9	Very high	91.5	Very high	8 Å²	8	17.2 Å²	17.2	5%	0.048	10%	0.096	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.5	-27.5	-178.6	75.8	0	0	0	0	113.2	L163 S167 Y173 A174 A405 Q406	L163-V171 HydrophobicContact CD2-CG2 4Å; S167-V171 PolarHBondContact O-N 3.26Å; V171-Y173 PolarHBondContact O-N 3.01Å; V171-A174 WeakPolarHBondContact O-CB 3.37Å; V171-A174 PolarHBondContact O-N 2.82Å; V171-A405 HydrophobicContact CG2-CB 4.39Å; V171-Q406 HydrophobicContact CG1-CG 3.94Å
172	G	89	Confident	91.7	Very high	1 Å²	1	19.2 Å²	19.2	1%	0.01	11%	0.105	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.1	-22.2	174.7	0	0	0	0	0	114.2	N170 A174 S175	N170-G172 PolarHBondContact O-N 3.38Å; G172-A174 PolarHBondContact O-N 3.29Å; G172-S175 PolarHBondContact O-OG 3.33Å
173	Y	93.1	Very high	91.8	Very high	54 Å²	54	20 Å²	20	21%	0.212	11%	0.11	C	C	.	.	H	α-helix	trans	-73	-10.4	171.3	-69.5	-74.5	0	0	0	113.2	L27 N170 V171 S175 T176 C177 A335	L27-Y173 HydrophobicContact CD1-CD2 4.32Å; L27-Y173 HydrophobicContact CD1-CE2 4.25Å; N170-Y173 HydrophobicContact CB-CD2 4.04Å; N170-Y173 WeakPolarHBondContact O-CB 3.47Å; N170-Y173 WeakPolarHBondContact O-CD2 3.06Å; N170-Y173 PolarHBondContact O-N 3.29Å; V171-Y173 PolarHBondContact O-N 3.01Å; Y173-S175 PolarHBondContact O-N 2.71Å; Y173-T176 WeakPolarHBondContact O-CB 3.44Å; Y173-T176 PolarHBondContact O-N 2.66Å; Y173-T176 VanDerWaalsContact O-N 3.13Å; Y173-C177 PolarHBondContact O-N 3.41Å; Y173-C177 PolarHBondContact O-SG 3.46Å; Y173-A335 HydrophobicContact CD1-CB 4.06Å; Y173-A335 HydrophobicContact CD2-CB 3.64Å; Y173-A335 HydrophobicContact CE1-CB 3.91Å; Y173-A335 HydrophobicContact CE2-CB 3.46Å; Y173-A335 VanDerWaalsContact CE2-CB 3.46Å; Y173-A335 HydrophobicContact CG-CB 3.94Å
174	A	93.7	Very high	92	Very high	4 Å²	4	20.2 Å²	20.2	3%	0.033	11%	0.114	C	C	.	.	H	α-helix	trans	-55.6	-37.8	173.6	0	0	0	0	0	111.5	A162 L166 V171 G172 C177 N178 A405	A162-A174 HydrophobicContact CB-CB 3.78Å; L166-A174 HydrophobicContact CD1-CB 4.05Å; V171-A174 WeakPolarHBondContact O-CB 3.37Å; V171-A174 PolarHBondContact O-N 2.82Å; G172-A174 PolarHBondContact O-N 3.29Å; A174-C177 PolarHBondContact O-N 3.26Å; A174-N178 WeakPolarHBondContact O-CB 3.44Å; A174-N178 PolarHBondContact O-N 3.24Å; A174-A405 HydrophobicContact CB-CB 4.18Å
175	S	93.4	Very high	92.3	Very high	2 Å²	2	17 Å²	17	1%	0.014	10%	0.095	C	C	.	.	H	α-helix	trans	-66.5	-44.4	176.4	64.2	0	0	0	0	112.1	G172 Y173 C177 N178 V179 V398 A402	G172-S175 PolarHBondContact O-OG 3.33Å; Y173-S175 PolarHBondContact O-N 2.71Å; S175-C177 VanDerWaalsContact C-N 3.29Å; S175-C177 PolarHBondContact O-N 3.05Å; S175-N178 PolarHBondContact O-N 2.88Å; S175-V179 VanDerWaalsContact O-CG2 3.31Å; S175-V179 WeakPolarHBondContact O-CG2 3.36Å; S175-V179 PolarHBondContact O-N 2.9Å; S175-V398 WeakPolarHBondContact CB-O 3.19Å; S175-V398 PolarHBondContact OG-O 3.12Å; S175-A402 VanDerWaalsContact CB-N 3.35Å; S175-A402 WeakPolarHBondContact OG-CB 3.24Å
176	T	94.4	Very high	92.6	Very high	10 Å²	10	21.4 Å²	21.4	6%	0.061	11%	0.112	C	C	.	.	H	α-helix	trans	-57.5	-45.1	174.1	-60.1	0	0	0	0	110.6	Y173 N178 V179 V180 P327 L328 G331	Y173-T176 WeakPolarHBondContact O-CB 3.44Å; Y173-T176 PolarHBondContact O-N 2.66Å; Y173-T176 VanDerWaalsContact O-N 3.13Å; T176-N178 PolarHBondContact O-N 3.2Å; T176-V179 PolarHBondContact O-N 3.19Å; T176-V180 HydrophobicContact CG2-CG2 4.1Å; T176-V180 VanDerWaalsContact O-CB 3.29Å; T176-V180 WeakPolarHBondContact O-CB 3.28Å; T176-V180 WeakPolarHBondContact O-CG2 3.48Å; T176-V180 PolarHBondContact O-N 3.12Å; T176-P327 HydrophobicContact CG2-CB 4.11Å; T176-P327 WeakPolarHBondContact CG2-O 3.35Å; T176-P327 PolarHBondContact OG1-O 3.47Å; T176-L328 HydrophobicContact CG2-CD2 4.1Å; T176-G331 WeakPolarHBondContact OG1-CA 3.28Å
177	C	95.8	Very high	92.7	Very high	3 Å²	3	23.7 Å²	23.7	2%	0.02	12%	0.121	C	C	.	.	H	α-helix	trans	-61	-44.7	177.8	-60.1	0	0	0	0	112	L37 V38 Y41 Y173 A174 S175 G181	L37-C177 HydrophobicContact CB-CB 4.08Å; V38-C177 HydrophobicContact CG2-CB 3.88Å; Y41-C177 VanDerWaalsContact CD2-C 3.43Å; Y41-C177 HydrophobicContact CD2-CB 3.96Å; Y41-C177 WeakPolarHBondContact CD2-O 3.5Å; Y41-C177 HydrophobicContact CE2-CB 3.95Å; Y173-C177 PolarHBondContact O-N 3.41Å; Y173-C177 PolarHBondContact O-SG 3.46Å; A174-C177 PolarHBondContact O-N 3.26Å; S175-C177 VanDerWaalsContact C-N 3.29Å; S175-C177 PolarHBondContact O-N 3.05Å; C177-G181 PolarHBondContact O-N 3.3Å
178	N	95.1	Very high	92.8	Very high	6 Å²	6	25.1 Å²	25.1	3%	0.032	13%	0.127	C	C	.	.	H	α-helix	trans	-59.3	-55.1	178.4	177.5	-81.1	0	0	0	111.2	Y41 D159 A174 S175 T176 Q182	Y41-N178 HydrophobicContact CD1-CB 4.2Å; Y41-N178 HydrophobicContact CD2-CB 4.14Å; Y41-N178 HydrophobicContact CE1-CB 3.91Å; Y41-N178 WeakPolarHBondContact CE1-ND2 3.38Å; Y41-N178 HydrophobicContact CE2-CB 3.83Å; Y41-N178 HydrophobicContact CG-CB 4.31Å; D159-N178 PolarHBondContact OD1-ND2 3.11Å; D159-N178 VanDerWaalsContact OD1-ND2 3.12Å; A174-N178 WeakPolarHBondContact O-CB 3.44Å; A174-N178 PolarHBondContact O-N 3.24Å; S175-N178 PolarHBondContact O-N 2.88Å; T176-N178 PolarHBondContact O-N 3.2Å; N178-Q182 WeakPolarHBondContact O-CB 3.26Å; N178-Q182 PolarHBondContact O-N 3.03Å
179	V	94.1	Very high	93.1	Very high	2 Å²	2	22 Å²	22	1%	0.012	11%	0.107	C	C	.	.	H	α-helix	trans	-64	-47.7	-176.5	-179.3	0	0	0	0	111.5	S175 T176 T183 P327 Y394 F397 V398	S175-V179 VanDerWaalsContact O-CG2 3.31Å; S175-V179 WeakPolarHBondContact O-CG2 3.36Å; S175-V179 PolarHBondContact O-N 2.9Å; T176-V179 PolarHBondContact O-N 3.19Å; V179-T183 WeakPolarHBondContact O-CB 3.23Å; V179-T183 PolarHBondContact O-N 2.89Å; V179-T183 PolarHBondContact O-OG1 3.35Å; V179-P327 HydrophobicContact CB-CG 4.21Å; V179-P327 HydrophobicContact CG1-CB 4.45Å; V179-P327 HydrophobicContact CG1-CG 3.65Å; V179-Y394 HydrophobicContact CG1-CD1 3.68Å; V179-Y394 HydrophobicContact CG1-CE1 3.44Å; V179-Y394 VanDerWaalsContact CG1-CE1 3.44Å; V179-F397 HydrophobicContact CG2-CD1 3.67Å; V179-F397 HydrophobicContact CG2-CE1 3.45Å; V179-F397 VanDerWaalsContact CG2-CE1 3.45Å; V179-V398 HydrophobicContact CB-CG2 4.27Å; V179-V398 HydrophobicContact CG1-CG2 4.33Å; V179-V398 HydrophobicContact CG2-CG2 3.8Å
180	V	95.8	Very high	93.2	Very high	14 Å²	14	20.3 Å²	20.3	9%	0.085	10%	0.099	C	C	.	.	H	α-helix	trans	-63.3	-51	-178.5	172.7	0	0	0	0	110.6	V38 T176 A184 I324 P327 L328	V38-V180 HydrophobicContact CG1-CG1 4.32Å; T176-V180 HydrophobicContact CG2-CG2 4.1Å; T176-V180 VanDerWaalsContact O-CB 3.29Å; T176-V180 WeakPolarHBondContact O-CB 3.28Å; T176-V180 WeakPolarHBondContact O-CG2 3.48Å; T176-V180 PolarHBondContact O-N 3.12Å; V180-A184 VanDerWaalsContact O-CB 3.26Å; V180-A184 WeakPolarHBondContact O-CB 3.26Å; V180-A184 PolarHBondContact O-N 2.88Å; V180-I324 HydrophobicContact CG1-CG2 4.24Å; V180-P327 HydrophobicContact CG2-CB 3.78Å; V180-P327 HydrophobicContact CG2-CG 4.28Å; V180-L328 HydrophobicContact CG1-CD2 4.41Å; V180-L328 HydrophobicContact CG2-CD2 3.79Å; V180-L328 HydrophobicContact CG2-CG 4.04Å
181	G	96.6	Very high	92.9	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-61.9	-56.6	-179.2	0	0	0	0	0	111.3	V38 L42 C177 T183 A184 G185	V38-G181 WeakPolarHBondContact O-CA 3.45Å; L42-G181 WeakPolarHBondContact CA-O 3.29Å; C177-G181 PolarHBondContact O-N 3.3Å; G181-T183 VanDerWaalsContact C-N 3.34Å; G181-T183 PolarHBondContact O-N 2.86Å; G181-A184 PolarHBondContact O-N 3.02Å; G181-G185 PolarHBondContact O-N 2.8Å
182	Q	95.5	Very high	92.6	Very high	48 Å²	48	22.9 Å²	22.9	22%	0.224	12%	0.115	C	C	.	.	H	α-helix	trans	-62.1	-40	-175.6	-169.6	-175.8	87	0	0	112.2	Y41 L48 N178 G185 Y186	Y41-Q182 WeakPolarHBondContact O-CA 3.41Å; Y41-Q182 PolarHBondContact O-N 2.85Å; L48-Q182 HydrophobicContact CD1-CG 4.07Å; N178-Q182 WeakPolarHBondContact O-CB 3.26Å; N178-Q182 PolarHBondContact O-N 3.03Å; Q182-G185 PolarHBondContact O-N 3.38Å; Q182-Y186 VanDerWaalsContact O-CB 3.26Å; Q182-Y186 WeakPolarHBondContact O-CB 3.37Å; Q182-Y186 PolarHBondContact O-N 3.46Å
183	T	94.5	Very high	92.3	Very high	16 Å²	16	23.6 Å²	23.6	10%	0.098	12%	0.118	C	C	.	.	H	α-helix	trans	-65.7	-45	176.9	-54.8	0	0	0	0	111.2	V179 G181 G185 Y186 F187 V320 E323 I324	V179-T183 WeakPolarHBondContact O-CB 3.23Å; V179-T183 PolarHBondContact O-N 2.89Å; V179-T183 PolarHBondContact O-OG1 3.35Å; G181-T183 VanDerWaalsContact C-N 3.34Å; G181-T183 PolarHBondContact O-N 2.86Å; T183-G185 PolarHBondContact O-N 3.45Å; T183-Y186 PolarHBondContact O-N 3.47Å; T183-F187 WeakPolarHBondContact O-CB 3.45Å; T183-F187 PolarHBondContact O-N 3.14Å; T183-V320 HydrophobicContact CG2-CG1 4.47Å; T183-E323 HydrophobicContact CG2-CB 3.85Å; T183-I324 HydrophobicContact CG2-CG1 3.84Å
184	A	95.4	Very high	91.5	Very high	20 Å²	20	22.9 Å²	22.9	17%	0.165	12%	0.118	C	C	.	.	H	α-helix	trans	-62.1	-43.9	176.4	0	0	0	0	0	111.7	L42 V180 G181 F187 L188 I324	L42-A184 HydrophobicContact CD1-CB 4.29Å; V180-A184 VanDerWaalsContact O-CB 3.26Å; V180-A184 WeakPolarHBondContact O-CB 3.26Å; V180-A184 PolarHBondContact O-N 2.88Å; G181-A184 PolarHBondContact O-N 3.02Å; A184-F187 PolarHBondContact O-N 2.91Å; A184-L188 WeakPolarHBondContact O-CB 3.44Å; A184-L188 VanDerWaalsContact O-CG 3.27Å; A184-L188 WeakPolarHBondContact O-CG 3.17Å; A184-L188 PolarHBondContact O-N 2.93Å; A184-I324 HydrophobicContact CB-CD1 4.05Å
185	G	95.8	Very high	90.6	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-62.3	-44.5	174.7	0	0	0	0	0	112.5	L42 G45 I46 G181 Q182 T183 F187 L188 G189	L42-G185 VanDerWaalsContact O-CA 3.31Å; L42-G185 WeakPolarHBondContact O-CA 3.32Å; G45-G185 CarbonylContact C-O 3.5Å; G45-G185 CarbonylContact O-C 3.54Å; I46-G185 WeakPolarHBondContact CD1-O 3.29Å; G181-G185 PolarHBondContact O-N 2.8Å; Q182-G185 PolarHBondContact O-N 3.38Å; T183-G185 PolarHBondContact O-N 3.45Å; G185-F187 VanDerWaalsContact C-N 3.34Å; G185-F187 PolarHBondContact O-N 3.24Å; G185-L188 PolarHBondContact O-N 3.36Å; G185-G189 PolarHBondContact O-N 3.31Å
186	Y	94	Very high	89.5	Confident	103 Å²	103	27.5 Å²	27.5	40%	0.404	14%	0.144	S	C	.	.	H	α-helix	trans	-60.5	-44.8	176.8	-179.6	-88.4	0	0	0	111.2	G45 L48 A52 Q182 T183 L188 G189 N190	G45-Y186 VanDerWaalsContact O-CA 3.3Å; G45-Y186 WeakPolarHBondContact O-CA 3.27Å; G45-Y186 PolarHBondContact O-N 3.33Å; L48-Y186 HydrophobicContact CB-CD2 4.15Å; A52-Y186 HydrophobicContact CB-CE2 3.64Å; A52-Y186 VanDerWaalsContact CB-OH 3.32Å; A52-Y186 WeakPolarHBondContact CB-OH 3.46Å; Q182-Y186 VanDerWaalsContact O-CB 3.26Å; Q182-Y186 WeakPolarHBondContact O-CB 3.37Å; Q182-Y186 PolarHBondContact O-N 3.46Å; T183-Y186 PolarHBondContact O-N 3.47Å; Y186-L188 PolarHBondContact O-N 3.49Å; Y186-G189 PolarHBondContact O-N 3.08Å; Y186-N190 HydrophobicContact CD1-CB 4.38Å; Y186-N190 HydrophobicContact CE1-CB 4.09Å; Y186-N190 WeakPolarHBondContact O-CB 3.44Å; Y186-N190 PolarHBondContact O-N 2.81Å
187	F	91.7	Very high	88.2	Confident	55 Å²	55	28.4 Å²	28.4	24%	0.241	15%	0.152	C	C	.	.	H	α-helix	trans	-60.6	-44.5	176.9	-179.7	-105.1	0	0	0	112.4	T183 A184 G185 N190 V191 V192 V320	T183-F187 WeakPolarHBondContact O-CB 3.45Å; T183-F187 PolarHBondContact O-N 3.14Å; A184-F187 PolarHBondContact O-N 2.91Å; G185-F187 VanDerWaalsContact C-N 3.34Å; G185-F187 PolarHBondContact O-N 3.24Å; F187-N190 PolarHBondContact O-N 3.25Å; F187-V191 HydrophobicContact CD2-CB 3.62Å; F187-V191 HydrophobicContact CD2-CG1 4.13Å; F187-V191 HydrophobicContact CD2-CG2 3.79Å; F187-V191 HydrophobicContact CE2-CB 3.54Å; F187-V191 HydrophobicContact CE2-CG1 3.5Å; F187-V191 VanDerWaalsContact CE2-CG1 3.5Å; F187-V191 HydrophobicContact CE2-CG2 3.95Å; F187-V191 HydrophobicContact CG-CB 4.44Å; F187-V191 HydrophobicContact CZ-CB 4.27Å; F187-V191 HydrophobicContact CZ-CG1 4.01Å; F187-V191 PolarHBondContact O-N 3.19Å; F187-V192 HydrophobicContact CD1-CG2 3.76Å; F187-V192 HydrophobicContact CE1-CG2 3.44Å; F187-V192 VanDerWaalsContact CE1-CG2 3.44Å; F187-V192 HydrophobicContact CZ-CG2 4.12Å; F187-V192 PolarHBondContact O-N 3.35Å; F187-V320 HydrophobicContact CB-CG1 3.96Å; F187-V320 HydrophobicContact CD2-CB 4.03Å; F187-V320 HydrophobicContact CD2-CG1 3.59Å; F187-V320 HydrophobicContact CD2-CG2 3.87Å; F187-V320 HydrophobicContact CE2-CB 4.29Å; F187-V320 HydrophobicContact CE2-CG1 4.16Å; F187-V320 HydrophobicContact CE2-CG2 4.31Å; F187-V320 HydrophobicContact CG-CG1 3.79Å
188	L	91.7	Very high	86.8	Confident	50 Å²	50	30.5 Å²	30.5	26%	0.262	17%	0.167	S	C	.	.	I	π-helix	trans	-62.2	-49.6	176	-73	167.1	0	0	0	111	L42 I46 A184 G185 Y186 N190 V192 F193 Y228 W232	L42-L188 HydrophobicContact CD1-CD1 4.29Å; L42-L188 HydrophobicContact CD2-CD1 4.31Å; L42-L188 HydrophobicContact CG-CD1 4.43Å; I46-L188 HydrophobicContact CD1-CB 3.35Å; I46-L188 HydrophobicContact CD1-CD1 4.15Å; I46-L188 HydrophobicContact CD1-CG 4.39Å; A184-L188 WeakPolarHBondContact O-CB 3.44Å; A184-L188 VanDerWaalsContact O-CG 3.27Å; A184-L188 WeakPolarHBondContact O-CG 3.17Å; A184-L188 PolarHBondContact O-N 2.93Å; G185-L188 PolarHBondContact O-N 3.36Å; Y186-L188 PolarHBondContact O-N 3.49Å; L188-N190 VanDerWaalsContact C-N 3.29Å; L188-N190 PolarHBondContact O-N 2.93Å; L188-V192 HydrophobicContact CD2-CG2 4.19Å; L188-F193 PolarHBondContact O-N 3.35Å; L188-Y228 VanDerWaalsContact C-OH 3.32Å; L188-Y228 PolarHBondContact O-OH 3.12Å; L188-W232 HydrophobicContact CB-CZ2 4.23Å; L188-W232 HydrophobicContact CD1-CH2 3.96Å; L188-W232 HydrophobicContact CD1-CZ2 3.95Å
189	G	89.4	Confident	84.9	Confident	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.192	C	C	.	.	I	π-helix	trans	-70.1	-21.8	-179.1	0	0	0	0	0	114.5	G49 L50 G185 Y186 F193	G49-G189 CarbonylContact C-O 3.54Å; L50-G189 VanDerWaalsContact CA-O 3.3Å; L50-G189 WeakPolarHBondContact CA-O 3.39Å; L50-G189 WeakPolarHBondContact CD2-O 3.49Å; L50-G189 PolarHBondContact N-O 3.21Å; L50-G189 VanDerWaalsContact N-O 3.14Å; G185-G189 PolarHBondContact O-N 3.31Å; Y186-G189 PolarHBondContact O-N 3.08Å; G189-F193 VanDerWaalsContact O-CB 3.31Å; G189-F193 WeakPolarHBondContact O-CB 3.25Å
190	N	87.8	Confident	83.3	Confident	13 Å²	13	42.3 Å²	42.3	7%	0.07	22%	0.22	C	C	.	.	I	π-helix	trans	-107.2	-77.2	-177.7	-169.2	-78.1	0	0	0	112.2	G49 A52 S53 Y186 F187 L188 F193 L194	G49-N190 WeakPolarHBondContact O-CB 3.36Å; G49-N190 PolarHBondContact O-ND2 3.21Å; A52-N190 VanDerWaalsContact CB-ND2 3.34Å; A52-N190 WeakPolarHBondContact CB-ND2 3.33Å; A52-N190 PolarHBondContact O-ND2 3.11Å; S53-N190 PolarHBondContact N-ND2 3.12Å; Y186-N190 HydrophobicContact CD1-CB 4.38Å; Y186-N190 HydrophobicContact CE1-CB 4.09Å; Y186-N190 WeakPolarHBondContact O-CB 3.44Å; Y186-N190 PolarHBondContact O-N 2.81Å; F187-N190 PolarHBondContact O-N 3.25Å; L188-N190 VanDerWaalsContact C-N 3.29Å; L188-N190 PolarHBondContact O-N 2.93Å; N190-F193 PolarHBondContact O-N 2.96Å; N190-L194 WeakPolarHBondContact O-CB 3.23Å; N190-L194 VanDerWaalsContact O-CG 3.28Å; N190-L194 WeakPolarHBondContact O-CG 3.28Å; N190-L194 PolarHBondContact O-N 3.37Å
191	V	83.8	Confident	81.7	Confident	41 Å²	41	45.1 Å²	45.1	25%	0.248	23%	0.231	C	C	.	.	I	π-helix	trans	-68.8	-46.7	-169.2	176.3	0	0	0	0	110.8	F187 L194 A195 V317	F187-V191 HydrophobicContact CD2-CB 3.62Å; F187-V191 HydrophobicContact CD2-CG1 4.13Å; F187-V191 HydrophobicContact CD2-CG2 3.79Å; F187-V191 HydrophobicContact CE2-CB 3.54Å; F187-V191 HydrophobicContact CE2-CG1 3.5Å; F187-V191 VanDerWaalsContact CE2-CG1 3.5Å; F187-V191 HydrophobicContact CE2-CG2 3.95Å; F187-V191 HydrophobicContact CG-CB 4.44Å; F187-V191 HydrophobicContact CZ-CB 4.27Å; F187-V191 HydrophobicContact CZ-CG1 4.01Å; F187-V191 PolarHBondContact O-N 3.19Å; V191-L194 PolarHBondContact O-N 3.08Å; V191-A195 WeakPolarHBondContact O-CB 3.39Å; V191-A195 PolarHBondContact O-N 2.91Å; V191-V317 HydrophobicContact CG1-CG2 4.43Å
192	V	83.5	Confident	79.8	Confident	38 Å²	38	45.5 Å²	45.5	23%	0.23	23%	0.234	C	C	.	.	I	π-helix	trans	-66.7	-43.7	179.1	177.5	0	0	0	0	110.5	F187 L188 L194 A195 L196 Y228	F187-V192 HydrophobicContact CD1-CG2 3.76Å; F187-V192 HydrophobicContact CE1-CG2 3.44Å; F187-V192 VanDerWaalsContact CE1-CG2 3.44Å; F187-V192 HydrophobicContact CZ-CG2 4.12Å; F187-V192 PolarHBondContact O-N 3.35Å; L188-V192 HydrophobicContact CD2-CG2 4.19Å; V192-L194 PolarHBondContact O-N 3.41Å; V192-A195 PolarHBondContact O-N 2.93Å; V192-L196 HydrophobicContact CG1-CD1 3.82Å; V192-L196 HydrophobicContact CG1-CG 4.24Å; V192-L196 WeakPolarHBondContact O-CB 3.43Å; V192-L196 WeakPolarHBondContact O-CG 3.19Å; V192-L196 PolarHBondContact O-N 2.8Å; V192-Y228 HydrophobicContact CG1-CE2 4.46Å
193	F	83	Confident	78.1	Confident	17 Å²	17	45.1 Å²	45.1	8%	0.075	23%	0.233	C	C	.	.	H	α-helix	trans	-56	-49.1	174.3	177.1	-105.3	0	0	0	112.4	L50 S53 L188 G189 N190 A197 A225 Y228	L50-F193 HydrophobicContact CD2-CB 4.42Å; L50-F193 HydrophobicContact CD2-CD1 4.11Å; L50-F193 HydrophobicContact CD2-CD2 3.92Å; L50-F193 HydrophobicContact CD2-CE1 4.36Å; L50-F193 HydrophobicContact CD2-CE2 4.16Å; L50-F193 HydrophobicContact CD2-CG 3.88Å; L50-F193 HydrophobicContact CD2-CZ 4.38Å; S53-F193 WeakPolarHBondContact OG-CD1 3.44Å; L188-F193 PolarHBondContact O-N 3.35Å; G189-F193 VanDerWaalsContact O-CB 3.31Å; G189-F193 WeakPolarHBondContact O-CB 3.25Å; N190-F193 PolarHBondContact O-N 2.96Å; F193-A197 WeakPolarHBondContact O-CB 3.12Å; F193-A197 PolarHBondContact O-N 2.65Å; F193-A197 VanDerWaalsContact O-N 3.1Å; F193-A225 HydrophobicContact CE2-CB 3.91Å; F193-A225 HydrophobicContact CZ-CB 4.12Å; F193-Y228 HydrophobicContact CB-CE1 4.11Å; F193-Y228 AromaticContact CD2-CD1 3.53Å; F193-Y228 HydrophobicContact CD2-CD1 3.53Å; F193-Y228 AromaticContact CD2-CE1 3.91Å; F193-Y228 HydrophobicContact CD2-CE1 3.91Å; F193-Y228 HydrophobicContact CD2-CG 4.17Å; F193-Y228 HydrophobicContact CE2-CD1 4.23Å; F193-Y228 HydrophobicContact CG-CD1 4.48Å; F193-Y228 HydrophobicContact CG-CE1 4.46Å
194	L	76.3	Confident	76.5	Confident	39 Å²	39	51.8 Å²	51.8	20%	0.204	26%	0.256	C	S	.	.	H	α-helix	trans	-67.7	-39.6	178.1	-73.4	171.7	0	0	0	112.8	L56 V57 N190 V191 V192 L196 A197 S198	L56-L194 HydrophobicContact CB-CD1 4.31Å; L56-L194 HydrophobicContact CD1-CD1 3.51Å; V57-L194 HydrophobicContact CG2-CD2 3.68Å; N190-L194 WeakPolarHBondContact O-CB 3.23Å; N190-L194 VanDerWaalsContact O-CG 3.28Å; N190-L194 WeakPolarHBondContact O-CG 3.28Å; N190-L194 PolarHBondContact O-N 3.37Å; V191-L194 PolarHBondContact O-N 3.08Å; V192-L194 PolarHBondContact O-N 3.41Å; L194-L196 VanDerWaalsContact C-N 3.34Å; L194-L196 PolarHBondContact O-N 2.87Å; L194-A197 CarbonylContact O-C 3.52Å; L194-A197 PolarHBondContact O-N 2.87Å; L194-A197 VanDerWaalsContact O-N 3.11Å; L194-S198 VanDerWaalsContact O-CB 3.28Å; L194-S198 WeakPolarHBondContact O-CB 3.36Å; L194-S198 PolarHBondContact O-N 2.84Å
195	A	74.5	Confident	74.8	Confident	16 Å²	16	57.5 Å²	57.5	13%	0.132	28%	0.275	C	S	.	.	H	α-helix	trans	-62.6	-42	177.8	0	0	0	0	0	111.4	V191 V192 A197 S198 F201	V191-A195 WeakPolarHBondContact O-CB 3.39Å; V191-A195 PolarHBondContact O-N 2.91Å; V192-A195 PolarHBondContact O-N 2.93Å; A195-A197 VanDerWaalsContact C-N 3.26Å; A195-A197 PolarHBondContact O-N 3.48Å; A195-S198 PolarHBondContact O-N 3.16Å; A195-F201 HydrophobicContact CB-CD1 3.73Å; A195-F201 HydrophobicContact CB-CE1 3.79Å; A195-F201 HydrophobicContact CB-CG 4.13Å; A195-F201 HydrophobicContact CB-CZ 4.21Å
196	L	71.2	Confident	73	Confident	87 Å²	87	62.3 Å²	62.3	46%	0.455	30%	0.3	S	S	.	.	H	α-helix	trans	-69.3	-23.7	174.5	-67.2	174.5	0	0	0	112.7	V192 L194 Y228	V192-L196 HydrophobicContact CG1-CD1 3.82Å; V192-L196 HydrophobicContact CG1-CG 4.24Å; V192-L196 WeakPolarHBondContact O-CB 3.43Å; V192-L196 WeakPolarHBondContact O-CG 3.19Å; V192-L196 PolarHBondContact O-N 2.8Å; L194-L196 VanDerWaalsContact C-N 3.34Å; L194-L196 PolarHBondContact O-N 2.87Å; L196-Y228 HydrophobicContact CD1-CD2 3.86Å; L196-Y228 HydrophobicContact CD1-CE2 3.91Å
197	A	67.2	Low	71.3	Confident	29 Å²	29	59.6 Å²	59.6	24%	0.24	29%	0.289	C	S	.	.	H	α-helix	trans	-88.1	-20.5	175.2	0	0	0	0	0	114	F193 L194 A195 I221	F193-A197 WeakPolarHBondContact O-CB 3.12Å; F193-A197 PolarHBondContact O-N 2.65Å; F193-A197 VanDerWaalsContact O-N 3.1Å; L194-A197 CarbonylContact O-C 3.52Å; L194-A197 PolarHBondContact O-N 2.87Å; L194-A197 VanDerWaalsContact O-N 3.11Å; A195-A197 VanDerWaalsContact C-N 3.26Å; A195-A197 PolarHBondContact O-N 3.48Å; A197-I221 HydrophobicContact CB-CG2 4.19Å
198	S	65.3	Low	69.9	Low	46 Å²	46	63.2 Å²	63.2	32%	0.322	32%	0.321	S	S	.	.			trans	-88.1	126.1	-171	178.3	0	0	0	0	113.9	L194 A195 E200 C202	L194-S198 VanDerWaalsContact O-CB 3.28Å; L194-S198 WeakPolarHBondContact O-CB 3.36Å; L194-S198 PolarHBondContact O-N 2.84Å; A195-S198 PolarHBondContact O-N 3.16Å; S198-E200 VanDerWaalsContact C-N 3.35Å; S198-E200 PolarHBondContact O-N 3.25Å; S198-E200 PolarHBondContact OG-N 3.47Å; S198-C202 PolarHBondContact O-N 3.32Å; S198-C202 PolarHBondContact O-SG 3.1Å
199	K	56.1	Low	68.4	Low	131 Å²	131	68.2 Å²	68.2	57%	0.57	34%	0.343	S	S	*	.	H	α-helix	trans	-59	-42	174	68.7	-174.7	-178.9	-177.4	0	113.2	N203	K199-N203 WeakPolarHBondContact O-CB 3.36Å; K199-N203 PolarHBondContact O-N 3.16Å; K199-N203 VanDerWaalsContact O-N 3.11Å; K199-N203 PolarHBondContact O-ND2 3.37Å
200	E	60.3	Low	66.8	Low	126 Å²	126	73.3 Å²	73.3	59%	0.589	38%	0.376	S	S	*	.	H	α-helix	trans	-79.6	-42	-168.3	-175.1	172.3	176.1	0	0	111.3	S198 C202 N203 R204	S198-E200 VanDerWaalsContact C-N 3.35Å; S198-E200 PolarHBondContact O-N 3.25Å; S198-E200 PolarHBondContact OG-N 3.47Å; E200-C202 VanDerWaalsContact C-N 3.31Å; E200-C202 PolarHBondContact O-N 2.79Å; E200-N203 PolarHBondContact O-N 3.36Å; E200-R204 WeakPolarHBondContact O-CB 3.42Å; E200-R204 PolarHBondContact O-N 3.45Å
201	F	62.8	Low	65.2	Low	72 Å²	72	77.2 Å²	77.2	32%	0.316	40%	0.397	S	S	.	.	H	α-helix	trans	-58.6	-45.3	174.4	-176.1	-91	0	0	0	111.1	A195 R204 Y205 L206	A195-F201 HydrophobicContact CB-CD1 3.73Å; A195-F201 HydrophobicContact CB-CE1 3.79Å; A195-F201 HydrophobicContact CB-CG 4.13Å; A195-F201 HydrophobicContact CB-CZ 4.21Å; F201-R204 PolarHBondContact O-N 2.96Å; F201-Y205 AromaticContact CD2-CD2 3.67Å; F201-Y205 HydrophobicContact CD2-CD2 3.67Å; F201-Y205 HydrophobicContact CD2-CE2 4.04Å; F201-Y205 AromaticContact CE2-CD2 3.65Å; F201-Y205 HydrophobicContact CE2-CD2 3.65Å; F201-Y205 HydrophobicContact CE2-CE2 4.06Å; F201-Y205 HydrophobicContact CE2-CG 4.35Å; F201-Y205 HydrophobicContact CG-CD2 4.22Å; F201-Y205 HydrophobicContact CZ-CD2 4.18Å; F201-Y205 HydrophobicContact CZ-CG 4.5Å; F201-Y205 PolarHBondContact O-N 3.47Å; F201-L206 HydrophobicContact CE1-CD1 4.4Å
202	C	56.5	Low	63.6	Low	9 Å²	9	83.7 Å²	83.7	6%	0.061	43%	0.43	C	S	.	.	I	π-helix	trans	-64.2	-44	178.1	-67.1	0	0	0	0	112.1	S198 E200 R204 L206 R207	S198-C202 PolarHBondContact O-N 3.32Å; S198-C202 PolarHBondContact O-SG 3.1Å; E200-C202 VanDerWaalsContact C-N 3.31Å; E200-C202 PolarHBondContact O-N 2.79Å; C202-R204 VanDerWaalsContact C-N 3.29Å; C202-R204 PolarHBondContact O-N 2.85Å; C202-L206 CarbonylContact O-C 3.41Å; C202-L206 WeakPolarHBondContact O-CA 3.47Å; C202-L206 PolarHBondContact O-N 3.39Å; C202-R207 WeakPolarHBondContact O-CB 3.46Å; C202-R207 WeakPolarHBondContact O-CG 3.01Å; C202-R207 PolarHBondContact O-N 2.87Å
203	N	59.7	Low	61.6	Low	40 Å²	40	90.9 Å²	90.9	21%	0.214	45%	0.453	C	S	.	.	I	π-helix	trans	-60.1	-37.7	175.7	-83.9	-20.7	0	0	0	112.9	K199 E200 R207 L211	K199-N203 WeakPolarHBondContact O-CB 3.36Å; K199-N203 PolarHBondContact O-N 3.16Å; K199-N203 VanDerWaalsContact O-N 3.11Å; K199-N203 PolarHBondContact O-ND2 3.37Å; E200-N203 PolarHBondContact O-N 3.36Å; N203-R207 WeakPolarHBondContact OD1-CD 3.13Å; N203-R207 PolarHBondContact OD1-NH1 3.43Å; N203-L211 PolarHBondContact ND2-O 3.37Å; N203-L211 PolarHBondContact OD1-N 3.07Å
204	R	61.2	Low	59.6	Low	156 Å²	156	90.4 Å²	90.4	59%	0.589	45%	0.453	S	S	*	.	I	π-helix	trans	-85.3	-32.3	-173.2	-168.2	171.2	-177.3	173.3	-3.2	114	E200 F201 C202	E200-R204 WeakPolarHBondContact O-CB 3.42Å; E200-R204 PolarHBondContact O-N 3.45Å; F201-R204 PolarHBondContact O-N 2.96Å; C202-R204 VanDerWaalsContact C-N 3.29Å; C202-R204 PolarHBondContact O-N 2.85Å
205	Y	59.5	Low	58	Low	139 Å²	139	92.4 Å²	92.4	55%	0.545	46%	0.462	S	S	.	.	I	π-helix	trans	-122.5	-23.7	-170.4	-64.5	-75	0	0	0	115.4	F201	F201-Y205 AromaticContact CD2-CD2 3.67Å; F201-Y205 HydrophobicContact CD2-CD2 3.67Å; F201-Y205 HydrophobicContact CD2-CE2 4.04Å; F201-Y205 AromaticContact CE2-CD2 3.65Å; F201-Y205 HydrophobicContact CE2-CD2 3.65Å; F201-Y205 HydrophobicContact CE2-CE2 4.06Å; F201-Y205 HydrophobicContact CE2-CG 4.35Å; F201-Y205 HydrophobicContact CG-CD2 4.22Å; F201-Y205 HydrophobicContact CZ-CD2 4.18Å; F201-Y205 HydrophobicContact CZ-CG 4.5Å; F201-Y205 PolarHBondContact O-N 3.47Å
206	L	58.2	Low	56.5	Low	102 Å²	102	94.9 Å²	94.9	53%	0.534	47%	0.47	S	S	.	.	I	π-helix	trans	-111.2	-19.3	-174.8	-62	175.4	0	0	0	113.3	F201 C202 M215	F201-L206 HydrophobicContact CE1-CD1 4.4Å; C202-L206 CarbonylContact O-C 3.41Å; C202-L206 WeakPolarHBondContact O-CA 3.47Å; C202-L206 PolarHBondContact O-N 3.39Å; L206-M215 HydrophobicContact CB-CE 4.32Å
207	R	57.1	Low	55.4	Low	45 Å²	45	93.2 Å²	93.2	17%	0.17	46%	0.464	C	S	.	.			trans	-109	143.6	-176.3	-73.5	172	151.9	177.7	-21	112	C202 N203 L211 R213 G214 M215	C202-R207 WeakPolarHBondContact O-CB 3.46Å; C202-R207 WeakPolarHBondContact O-CG 3.01Å; C202-R207 PolarHBondContact O-N 2.87Å; N203-R207 WeakPolarHBondContact OD1-CD 3.13Å; N203-R207 PolarHBondContact OD1-NH1 3.43Å; R207-L211 VanDerWaalsContact NH2-CD1 3.29Å; R207-R213 PolarHBondContact NH1-O 3.29Å; R207-R213 PolarHBondContact NH2-O 2.9Å; R207-G214 PolarHBondContact NH1-O 2.89Å; R207-G214 PolarHBondContact NH2-O 3.22Å; R207-M215 HydrophobicContact CG-CE 4.35Å; R207-M215 VanDerWaalsContact NH1-N 3.17Å; R207-M215 VanDerWaalsContact NH2-N 3.11Å
208	S	62.7	Low	54.5	Low	131 Å²	131	95 Å²	95	92%	0.916	47%	0.469	S	S	*	.	S	Bend	trans	-83.9	-29.6	170.3	-50.8	0	0	0	0	113
209	E	60.4	Low	53.9	Low	155 Å²	155	96 Å²	96	72%	0.724	48%	0.475	S	S	*	.	S	Bend	trans	-118.5	129.1	176.6	-69.6	-174.1	169.8	0	0	110.9
210	P	55.3	Low	54	Low	107 Å²	107	93.3 Å²	93.3	70%	0.695	47%	0.465	S	S	*	.			trans	-73.5	134.9	178.2	29.8	-32.9	0	0	0	110.9
211	L	54.3	Low	53.9	Low	96 Å²	96	89.2 Å²	89.2	50%	0.503	45%	0.447	S	S	.	.			trans	-123.2	140.8	174.2	-72.9	161.9	0	0	0	109.8	N203 R207 R213	N203-L211 PolarHBondContact ND2-O 3.37Å; N203-L211 PolarHBondContact OD1-N 3.07Å; R207-L211 VanDerWaalsContact NH2-CD1 3.29Å; L211-R213 CarbonylContact C-O 3.53Å; L211-R213 WeakPolarHBondContact CB-O 3.33Å; L211-R213 PolarHBondContact O-N 2.99Å
212	D	51.2	Low	53.8	Low	177 Å²	177	86.4 Å²	86.4	95%	0.947	44%	0.435	S	S	*	.	S	Bend	trans	-68.4	5.1	174.6	-77.8	-24.6	0	0	0	113.8
213	R	41.8	Very low	54.2	Low	188 Å²	188	89.4 Å²	89.4	71%	0.709	45%	0.45	S	S	*	.	S	Bend	trans	-123.8	144.9	171.1	-57.3	178.7	-175.8	174.2	1	106	R207 L211	R207-R213 PolarHBondContact NH1-O 3.29Å; R207-R213 PolarHBondContact NH2-O 2.9Å; L211-R213 CarbonylContact C-O 3.53Å; L211-R213 WeakPolarHBondContact CB-O 3.33Å; L211-R213 PolarHBondContact O-N 2.99Å
214	G	39.7	Very low	54.7	Low	8 Å²	8	89.3 Å²	89.3	8%	0.082	45%	0.449	C	S	.	.			trans	-54.4	176.4	170.2	0	0	0	0	0	111.4	R207 F216	R207-G214 PolarHBondContact NH1-O 2.89Å; R207-G214 PolarHBondContact NH2-O 3.22Å; G214-F216 CarbonylContact C-O 3.58Å; G214-F216 PolarHBondContact O-N 2.66Å
215	M	42.6	Very low	55.4	Low	81 Å²	81	82.2 Å²	82.2	40%	0.399	42%	0.424	S	S	.	.	S	Bend	trans	-46.6	-22.5	171.7	-169.2	176.6	-65.3	0	0	112.1	L206 R207	L206-M215 HydrophobicContact CB-CE 4.32Å; R207-M215 HydrophobicContact CG-CE 4.35Å; R207-M215 VanDerWaalsContact NH1-N 3.17Å; R207-M215 VanDerWaalsContact NH2-N 3.11Å
216	F	43	Very low	56.5	Low	68 Å²	68	76.2 Å²	76.2	30%	0.298	40%	0.403	S	S	.	.	S	Bend	trans	-136.2	136.8	-169.9	-71.8	-56.2	0	0	0	109.1	G214 Q220 I221 N224	G214-F216 CarbonylContact C-O 3.58Å; G214-F216 PolarHBondContact O-N 2.66Å; F216-Q220 HydrophobicContact CB-CB 3.21Å; F216-Q220 HydrophobicContact CB-CG 4.37Å; F216-Q220 HydrophobicContact CD1-CB 3.58Å; F216-Q220 HydrophobicContact CD1-CG 4.04Å; F216-Q220 HydrophobicContact CG-CB 3.73Å; F216-I221 HydrophobicContact CB-CG1 4.31Å; F216-N224 WeakPolarHBondContact CD2-ND2 3.46Å; F216-N224 WeakPolarHBondContact CE2-ND2 3.48Å; F216-N224 VanDerWaalsContact CG-ND2 3.29Å; F216-N224 WeakPolarHBondContact CG-ND2 3.32Å
217	T	48.6	Very low	57.7	Low	51 Å²	51	77.4 Å²	77.4	31%	0.313	40%	0.404	S	S	.	.			trans	-50.8	163.9	165.2	48.5	0	0	0	0	110.7	S219 Q220 I221	T217-S219 PolarHBondContact O-N 3.38Å; T217-S219 VanDerWaalsContact O-N 3.15Å; T217-S219 PolarHBondContact OG1-OG 3.5Å; T217-Q220 CarbonylContact O-C 3.56Å; T217-Q220 WeakPolarHBondContact O-CA 3.39Å; T217-Q220 PolarHBondContact O-N 3.28Å; T217-Q220 WeakPolarHBondContact OG1-CG 3.38Å; T217-Q220 PolarHBondContact OG1-N 3.1Å; T217-Q220 PolarHBondContact OG1-OE1 3.17Å; T217-I221 PolarHBondContact O-N 2.88Å
218	L	48.8	Very low	59.1	Low	68 Å²	68	76.7 Å²	76.7	36%	0.356	40%	0.401	S	S	.	.	H	α-helix	trans	-48.3	-44.7	173.7	-175.1	72	0	0	0	111	Q220 I221 L222	L218-Q220 VanDerWaalsContact C-N 3.32Å; L218-Q220 PolarHBondContact O-N 3.24Å; L218-I221 PolarHBondContact O-N 2.8Å; L218-L222 HydrophobicContact CG-CD1 4.31Å; L218-L222 WeakPolarHBondContact O-CG 3.41Å; L218-L222 PolarHBondContact O-N 3.18Å
219	S	52.5	Low	60.4	Low	65 Å²	65	70.8 Å²	70.8	46%	0.455	36%	0.36	S	S	.	.	H	α-helix	trans	-56.8	-41.4	171.7	55.5	0	0	0	0	113.2	T217 L222 I223	T217-S219 PolarHBondContact O-N 3.38Å; T217-S219 VanDerWaalsContact O-N 3.15Å; T217-S219 PolarHBondContact OG1-OG 3.5Å; S219-L222 PolarHBondContact O-N 2.93Å; S219-I223 WeakPolarHBondContact O-CB 3.42Å; S219-I223 VanDerWaalsContact O-CD1 3.24Å; S219-I223 WeakPolarHBondContact O-CD1 3.38Å; S219-I223 WeakPolarHBondContact O-CG1 3.48Å; S219-I223 PolarHBondContact O-N 3.01Å
220	Q	57.5	Low	61.8	Low	76 Å²	76	69.1 Å²	69.1	36%	0.355	35%	0.347	S	S	.	.	H	α-helix	trans	-76.4	-29.6	179.6	-67.8	167	-26.9	0	0	113.2	F216 T217 L218 I223 N224	F216-Q220 HydrophobicContact CB-CB 3.21Å; F216-Q220 HydrophobicContact CB-CG 4.37Å; F216-Q220 HydrophobicContact CD1-CB 3.58Å; F216-Q220 HydrophobicContact CD1-CG 4.04Å; F216-Q220 HydrophobicContact CG-CB 3.73Å; T217-Q220 CarbonylContact O-C 3.56Å; T217-Q220 WeakPolarHBondContact O-CA 3.39Å; T217-Q220 PolarHBondContact O-N 3.28Å; T217-Q220 WeakPolarHBondContact OG1-CG 3.38Å; T217-Q220 PolarHBondContact OG1-N 3.1Å; T217-Q220 PolarHBondContact OG1-OE1 3.17Å; L218-Q220 VanDerWaalsContact C-N 3.32Å; L218-Q220 PolarHBondContact O-N 3.24Å; Q220-I223 PolarHBondContact O-N 3.07Å; Q220-N224 WeakPolarHBondContact O-CB 3.19Å; Q220-N224 PolarHBondContact O-N 3.23Å; Q220-N224 PolarHBondContact O-ND2 3.02Å
221	I	58.5	Low	63.6	Low	40 Å²	40	69.4 Å²	69.4	21%	0.205	34%	0.338	C	S	.	.	H	α-helix	trans	-63.3	-46.5	169.6	-70.3	169.6	0	0	0	109.5	A197 F216 T217 L218 N224 A225	A197-I221 HydrophobicContact CB-CG2 4.19Å; F216-I221 HydrophobicContact CB-CG1 4.31Å; T217-I221 PolarHBondContact O-N 2.88Å; L218-I221 PolarHBondContact O-N 2.8Å; I221-N224 PolarHBondContact O-N 3.24Å; I221-A225 WeakPolarHBondContact O-CB 3.28Å; I221-A225 PolarHBondContact O-N 3.39Å
222	L	60.7	Low	65.5	Low	13 Å²	13	65.7 Å²	65.7	7%	0.068	32%	0.317	C	S	.	.	H	α-helix	trans	-61.8	-46.2	175	-62.5	167.8	0	0	0	111.1	V121 D122 L125 L218 S219 N224 A225 A226	V121-L222 HydrophobicContact CG1-CB 4.2Å; V121-L222 HydrophobicContact CG1-CD2 3.81Å; D122-L222 WeakPolarHBondContact OD1-CB 3.47Å; D122-L222 WeakPolarHBondContact OD1-CD1 3.12Å; L125-L222 HydrophobicContact CB-CD2 3.16Å; L125-L222 HydrophobicContact CD1-CD2 4.05Å; L125-L222 HydrophobicContact CG-CD2 4.23Å; L218-L222 HydrophobicContact CG-CD1 4.31Å; L218-L222 WeakPolarHBondContact O-CG 3.41Å; L218-L222 PolarHBondContact O-N 3.18Å; S219-L222 PolarHBondContact O-N 2.93Å; L222-N224 VanDerWaalsContact C-N 3.27Å; L222-N224 PolarHBondContact O-N 3.45Å; L222-A225 PolarHBondContact O-N 2.7Å; L222-A226 VanDerWaalsContact O-CB 3.28Å; L222-A226 WeakPolarHBondContact O-CB 3.41Å; L222-A226 PolarHBondContact O-N 3.31Å
223	I	64.3	Low	67.6	Low	72 Å²	72	57.3 Å²	57.3	37%	0.369	27%	0.273	S	S	.	.	H	α-helix	trans	-58.4	-39	174.3	-71.4	159.8	0	0	0	111	S219 Q220 K227	S219-I223 WeakPolarHBondContact O-CB 3.42Å; S219-I223 VanDerWaalsContact O-CD1 3.24Å; S219-I223 WeakPolarHBondContact O-CD1 3.38Å; S219-I223 WeakPolarHBondContact O-CG1 3.48Å; S219-I223 PolarHBondContact O-N 3.01Å; Q220-I223 PolarHBondContact O-N 3.07Å; I223-K227 HydrophobicContact CG2-CD 3.86Å; I223-K227 HydrophobicContact CG2-CG 4.32Å; I223-K227 VanDerWaalsContact O-CB 3.3Å; I223-K227 WeakPolarHBondContact O-CB 3.34Å; I223-K227 WeakPolarHBondContact O-CG 3.43Å; I223-K227 PolarHBondContact O-N 3.02Å
224	N	71.5	Confident	70.2	Confident	38 Å²	38	51.7 Å²	51.7	20%	0.203	26%	0.256	C	S	.	.	H	α-helix	trans	-72.1	-41.4	178.7	-73.6	-19.6	0	0	0	112.5	F216 Q220 I221 L222 A226 K227 Y228	F216-N224 WeakPolarHBondContact CD2-ND2 3.46Å; F216-N224 WeakPolarHBondContact CE2-ND2 3.48Å; F216-N224 VanDerWaalsContact CG-ND2 3.29Å; F216-N224 WeakPolarHBondContact CG-ND2 3.32Å; Q220-N224 WeakPolarHBondContact O-CB 3.19Å; Q220-N224 PolarHBondContact O-N 3.23Å; Q220-N224 PolarHBondContact O-ND2 3.02Å; I221-N224 PolarHBondContact O-N 3.24Å; L222-N224 VanDerWaalsContact C-N 3.27Å; L222-N224 PolarHBondContact O-N 3.45Å; N224-A226 VanDerWaalsContact C-N 3.31Å; N224-K227 PolarHBondContact O-N 3.35Å; N224-Y228 VanDerWaalsContact O-CB 3.25Å; N224-Y228 WeakPolarHBondContact O-CB 3.13Å; N224-Y228 PolarHBondContact O-N 2.86Å
225	A	75.7	Confident	72.9	Confident	6 Å²	6	52.7 Å²	52.7	5%	0.05	26%	0.26	C	S	.	.	H	α-helix	trans	-61.3	-43.2	172.6	0	0	0	0	0	110.7	V121 F193 I221 L222 Y228 L229	V121-A225 HydrophobicContact CG1-CB 3.87Å; F193-A225 HydrophobicContact CE2-CB 3.91Å; F193-A225 HydrophobicContact CZ-CB 4.12Å; I221-A225 WeakPolarHBondContact O-CB 3.28Å; I221-A225 PolarHBondContact O-N 3.39Å; L222-A225 PolarHBondContact O-N 2.7Å; A225-Y228 PolarHBondContact O-N 3.4Å; A225-L229 WeakPolarHBondContact O-CB 3.38Å; A225-L229 WeakPolarHBondContact O-CG 3.05Å; A225-L229 PolarHBondContact O-N 3.48Å
226	A	81.3	Confident	75.5	Confident	14 Å²	14	48.8 Å²	48.8	12%	0.116	24%	0.241	C	C	.	.	H	α-helix	trans	-60.9	-47.7	173.8	0	0	0	0	0	111.5	S118 V121 L222 N224 Y228 L229 Y230	S118-A226 WeakPolarHBondContact CB-O 3.45Å; S118-A226 VanDerWaalsContact O-CB 3.26Å; S118-A226 WeakPolarHBondContact O-CB 3.46Å; S118-A226 VanDerWaalsContact OG-C 3.28Å; S118-A226 WeakPolarHBondContact OG-CA 3.34Å; S118-A226 PolarHBondContact OG-O 3.05Å; V121-A226 HydrophobicContact CB-CB 4.35Å; V121-A226 HydrophobicContact CG2-CB 4.16Å; L222-A226 VanDerWaalsContact O-CB 3.28Å; L222-A226 WeakPolarHBondContact O-CB 3.41Å; L222-A226 PolarHBondContact O-N 3.31Å; N224-A226 VanDerWaalsContact C-N 3.31Å; A226-Y228 VanDerWaalsContact C-N 3.32Å; A226-Y228 PolarHBondContact O-N 3.34Å; A226-L229 PolarHBondContact O-N 2.87Å; A226-Y230 WeakPolarHBondContact O-CB 3.43Å; A226-Y230 PolarHBondContact O-N 3.13Å
227	K	84.1	Confident	78.1	Confident	127 Å²	127	48.6 Å²	48.6	55%	0.552	24%	0.241	S	C	*	.	H	α-helix	trans	-61.3	-38.5	175.2	-77.4	171	179.9	175.2	0	112.5	I223 N224 Y230 F231	I223-K227 HydrophobicContact CG2-CD 3.86Å; I223-K227 HydrophobicContact CG2-CG 4.32Å; I223-K227 VanDerWaalsContact O-CB 3.3Å; I223-K227 WeakPolarHBondContact O-CB 3.34Å; I223-K227 WeakPolarHBondContact O-CG 3.43Å; I223-K227 PolarHBondContact O-N 3.02Å; N224-K227 PolarHBondContact O-N 3.35Å; K227-Y230 PolarHBondContact O-N 3.22Å; K227-F231 VanDerWaalsContact O-CB 3.32Å; K227-F231 WeakPolarHBondContact O-CB 3.34Å; K227-F231 PolarHBondContact O-N 3.13Å
228	Y	86.9	Confident	80.4	Confident	29 Å²	29	49.7 Å²	49.7	11%	0.114	25%	0.247	C	C	.	.	H	α-helix	trans	-66.2	-46.4	178.4	-172.3	-91.9	0	0	0	111.2	L188 V192 F193 L196 N224 A225 A226 Y230 F231 W232	L188-Y228 VanDerWaalsContact C-OH 3.32Å; L188-Y228 PolarHBondContact O-OH 3.12Å; V192-Y228 HydrophobicContact CG1-CE2 4.46Å; F193-Y228 HydrophobicContact CB-CE1 4.11Å; F193-Y228 AromaticContact CD2-CD1 3.53Å; F193-Y228 HydrophobicContact CD2-CD1 3.53Å; F193-Y228 AromaticContact CD2-CE1 3.91Å; F193-Y228 HydrophobicContact CD2-CE1 3.91Å; F193-Y228 HydrophobicContact CD2-CG 4.17Å; F193-Y228 HydrophobicContact CE2-CD1 4.23Å; F193-Y228 HydrophobicContact CG-CD1 4.48Å; F193-Y228 HydrophobicContact CG-CE1 4.46Å; L196-Y228 HydrophobicContact CD1-CD2 3.86Å; L196-Y228 HydrophobicContact CD1-CE2 3.91Å; N224-Y228 VanDerWaalsContact O-CB 3.25Å; N224-Y228 WeakPolarHBondContact O-CB 3.13Å; N224-Y228 PolarHBondContact O-N 2.86Å; A225-Y228 PolarHBondContact O-N 3.4Å; A226-Y228 VanDerWaalsContact C-N 3.32Å; A226-Y228 PolarHBondContact O-N 3.34Å; Y228-Y230 VanDerWaalsContact C-N 3.35Å; Y228-F231 WeakPolarHBondContact O-CB 3.49Å; Y228-F231 PolarHBondContact O-N 2.92Å; Y228-W232 AromaticContact CD1-CD1 3.65Å; Y228-W232 AromaticContact CD1-NE1 3.91Å; Y228-W232 AromaticContact CE1-CD1 3.3Å; Y228-W232 AromaticContact CE1-NE1 3.16Å; Y228-W232 AromaticContact CE2-NE1 3.73Å; Y228-W232 AromaticContact CZ-CD1 3.69Å; Y228-W232 AromaticContact CZ-NE1 3.04Å; Y228-W232 VanDerWaalsContact O-CD1 3.24Å; Y228-W232 PolarHBondContact O-N 3.36Å; Y228-W232 PolarHBondContact OH-NE1 2.94Å
229	L	89.6	Confident	82.7	Confident	8 Å²	8	46.9 Å²	46.9	4%	0.042	23%	0.233	C	C	.	.	H	α-helix	trans	-64.6	-39.7	174.1	-69.9	171	0	0	0	111.9	L50 L117 V121 A225 A226 W232 A233	L50-L229 HydrophobicContact CD1-CD2 3.71Å; L50-L229 HydrophobicContact CD2-CD2 3.95Å; L117-L229 HydrophobicContact CB-CD1 3.87Å; V121-L229 HydrophobicContact CG2-CD1 3.63Å; A225-L229 WeakPolarHBondContact O-CB 3.38Å; A225-L229 WeakPolarHBondContact O-CG 3.05Å; A225-L229 PolarHBondContact O-N 3.48Å; A226-L229 PolarHBondContact O-N 2.87Å; L229-W232 PolarHBondContact O-N 3.32Å; L229-A233 WeakPolarHBondContact O-CB 3.3Å; L229-A233 PolarHBondContact O-N 2.93Å
230	Y	90.8	Very high	84.8	Confident	119 Å²	119	43.8 Å²	43.8	47%	0.467	21%	0.212	S	C	.	.	H	α-helix	trans	-62.9	-43.3	175.4	-178.1	-104.1	0	0	0	111.8	L115 A226 K227 Y228 A233 I234	L115-Y230 HydrophobicContact CD1-CD2 3.49Å; L115-Y230 VanDerWaalsContact CD1-CD2 3.49Å; L115-Y230 HydrophobicContact CD1-CE2 3.71Å; A226-Y230 WeakPolarHBondContact O-CB 3.43Å; A226-Y230 PolarHBondContact O-N 3.13Å; K227-Y230 PolarHBondContact O-N 3.22Å; Y228-Y230 VanDerWaalsContact C-N 3.35Å; Y230-A233 WeakPolarHBondContact O-CB 3.4Å; Y230-A233 PolarHBondContact O-N 2.93Å; Y230-I234 HydrophobicContact CD1-CD1 3.75Å; Y230-I234 HydrophobicContact CE1-CD1 3.23Å; Y230-I234 HydrophobicContact CE1-CG1 4.2Å; Y230-I234 HydrophobicContact CE2-CD1 4.43Å; Y230-I234 WeakPolarHBondContact O-CG1 3.44Å; Y230-I234 PolarHBondContact O-N 3.46Å
231	F	92.9	Very high	86.6	Confident	113 Å²	113	42.7 Å²	42.7	50%	0.496	21%	0.21	S	C	.	.	H	α-helix	trans	-57.1	-51.4	174	167.6	-98.6	0	0	0	110.9	K227 Y228 A233 I234 V235	K227-F231 VanDerWaalsContact O-CB 3.32Å; K227-F231 WeakPolarHBondContact O-CB 3.34Å; K227-F231 PolarHBondContact O-N 3.13Å; Y228-F231 WeakPolarHBondContact O-CB 3.49Å; Y228-F231 PolarHBondContact O-N 2.92Å; F231-A233 VanDerWaalsContact C-N 3.33Å; F231-A233 PolarHBondContact O-N 2.74Å; F231-I234 PolarHBondContact O-N 3.34Å; F231-V235 HydrophobicContact CD1-CG2 4.41Å; F231-V235 HydrophobicContact CD2-CG2 4.48Å; F231-V235 HydrophobicContact CE1-CG2 3.96Å; F231-V235 HydrophobicContact CE2-CG2 4.04Å; F231-V235 HydrophobicContact CZ-CG2 3.76Å; F231-V235 WeakPolarHBondContact O-CG2 3.38Å; F231-V235 PolarHBondContact O-N 3.4Å
232	W	94.3	Very high	88.4	Confident	18 Å²	18	45 Å²	45	7%	0.068	22%	0.222	C	C	.	.	H	α-helix	trans	-64.5	-37.4	177.8	-76.2	111.6	0	0	0	112.4	L42 L43 I46 M114 L188 Y228 L229 I234 V235 F236	L42-W232 HydrophobicContact CD2-CH2 3.85Å; L42-W232 HydrophobicContact CD2-CZ3 3.95Å; L43-W232 HydrophobicContact CD2-CE3 4.31Å; L43-W232 HydrophobicContact CD2-CZ3 4.09Å; I46-W232 HydrophobicContact CD1-CD2 4.06Å; I46-W232 HydrophobicContact CD1-CE3 4.3Å; I46-W232 HydrophobicContact CD1-CH2 3.68Å; I46-W232 HydrophobicContact CD1-CZ2 3.38Å; I46-W232 HydrophobicContact CD1-CZ3 4.12Å; I46-W232 HydrophobicContact CG1-CD2 4.21Å; I46-W232 HydrophobicContact CG1-CE3 4.1Å; I46-W232 HydrophobicContact CG1-CH2 4.1Å; I46-W232 HydrophobicContact CG1-CZ2 4.2Å; I46-W232 HydrophobicContact CG1-CZ3 4.04Å; I46-W232 HydrophobicContact CG2-CD2 4.19Å; I46-W232 HydrophobicContact CG2-CG 4.15Å; M114-W232 HydrophobicContact SD-CB 3.62Å; L188-W232 HydrophobicContact CB-CZ2 4.23Å; L188-W232 HydrophobicContact CD1-CH2 3.96Å; L188-W232 HydrophobicContact CD1-CZ2 3.95Å; Y228-W232 AromaticContact CD1-CD1 3.65Å; Y228-W232 AromaticContact CD1-NE1 3.91Å; Y228-W232 AromaticContact CE1-CD1 3.3Å; Y228-W232 AromaticContact CE1-NE1 3.16Å; Y228-W232 AromaticContact CE2-NE1 3.73Å; Y228-W232 AromaticContact CZ-CD1 3.69Å; Y228-W232 AromaticContact CZ-NE1 3.04Å; Y228-W232 VanDerWaalsContact O-CD1 3.24Å; Y228-W232 PolarHBondContact O-N 3.36Å; Y228-W232 PolarHBondContact OH-NE1 2.94Å; L229-W232 PolarHBondContact O-N 3.32Å; W232-I234 VanDerWaalsContact C-N 3.33Å; W232-I234 PolarHBondContact O-N 2.87Å; W232-V235 HydrophobicContact CE3-CB 4.11Å; W232-V235 HydrophobicContact CE3-CG1 4.06Å; W232-V235 HydrophobicContact CE3-CG2 4.44Å; W232-V235 HydrophobicContact CZ3-CG1 4.06Å; W232-V235 PolarHBondContact O-N 3.2Å; W232-V235 VanDerWaalsContact O-N 3.12Å; W232-F236 VanDerWaalsContact O-CD2 3.32Å; W232-F236 WeakPolarHBondContact O-CD2 3.49Å; W232-F236 PolarHBondContact O-N 3.36Å
233	A	94.8	Very high	90	Very high	1 Å²	1	44.8 Å²	44.8	1%	0.008	22%	0.222	C	C	.	.	H	α-helix	trans	-55.8	-48	173.2	0	0	0	0	0	111.5	G111 M114 L115 L229 Y230 F231 V235 F236 F237	G111-A233 VanDerWaalsContact O-CB 3.31Å; G111-A233 WeakPolarHBondContact O-CB 3.47Å; M114-A233 HydrophobicContact CB-CB 3.98Å; L115-A233 HydrophobicContact CB-CB 3.96Å; L229-A233 WeakPolarHBondContact O-CB 3.3Å; L229-A233 PolarHBondContact O-N 2.93Å; Y230-A233 WeakPolarHBondContact O-CB 3.4Å; Y230-A233 PolarHBondContact O-N 2.93Å; F231-A233 VanDerWaalsContact C-N 3.33Å; F231-A233 PolarHBondContact O-N 2.74Å; A233-V235 VanDerWaalsContact C-N 3.34Å; A233-V235 PolarHBondContact O-N 3.44Å; A233-F236 PolarHBondContact O-N 2.77Å; A233-F237 HydrophobicContact CB-CE2 4.36Å; A233-F237 WeakPolarHBondContact O-CD2 3.34Å; A233-F237 PolarHBondContact O-N 3.29Å
234	I	95.9	Very high	91.4	Very high	71 Å²	71	44.1 Å²	44.1	36%	0.364	22%	0.219	S	C	.	.	H	α-helix	trans	-59.8	-44.4	175	-68.2	168.8	0	0	0	111.2	Y230 F231 W232 F236 F237 T238	Y230-I234 HydrophobicContact CD1-CD1 3.75Å; Y230-I234 HydrophobicContact CE1-CD1 3.23Å; Y230-I234 HydrophobicContact CE1-CG1 4.2Å; Y230-I234 HydrophobicContact CE2-CD1 4.43Å; Y230-I234 WeakPolarHBondContact O-CG1 3.44Å; Y230-I234 PolarHBondContact O-N 3.46Å; F231-I234 PolarHBondContact O-N 3.34Å; W232-I234 VanDerWaalsContact C-N 3.33Å; W232-I234 PolarHBondContact O-N 2.87Å; I234-F236 VanDerWaalsContact C-N 3.32Å; I234-F236 PolarHBondContact O-N 3.41Å; I234-F237 PolarHBondContact O-N 3.26Å; I234-T238 VanDerWaalsContact O-CB 3.28Å; I234-T238 WeakPolarHBondContact O-CB 3.37Å; I234-T238 PolarHBondContact O-N 3.16Å; I234-T238 PolarHBondContact O-OG1 3.04Å
235	V	96.4	Very high	92.4	Very high	28 Å²	28	48.1 Å²	48.1	17%	0.17	24%	0.239	C	C	.	.	H	α-helix	trans	-60.5	-43.5	178	173.2	0	0	0	0	110.5	F39 L43 F231 W232 A233 S239	F39-V235 HydrophobicContact CZ-CG1 4.03Å; L43-V235 HydrophobicContact CD2-CG1 3.87Å; F231-V235 HydrophobicContact CD1-CG2 4.41Å; F231-V235 HydrophobicContact CD2-CG2 4.48Å; F231-V235 HydrophobicContact CE1-CG2 3.96Å; F231-V235 HydrophobicContact CE2-CG2 4.04Å; F231-V235 HydrophobicContact CZ-CG2 3.76Å; F231-V235 WeakPolarHBondContact O-CG2 3.38Å; F231-V235 PolarHBondContact O-N 3.4Å; W232-V235 HydrophobicContact CE3-CB 4.11Å; W232-V235 HydrophobicContact CE3-CG1 4.06Å; W232-V235 HydrophobicContact CE3-CG2 4.44Å; W232-V235 HydrophobicContact CZ3-CG1 4.06Å; W232-V235 PolarHBondContact O-N 3.2Å; W232-V235 VanDerWaalsContact O-N 3.12Å; A233-V235 VanDerWaalsContact C-N 3.34Å; A233-V235 PolarHBondContact O-N 3.44Å; V235-S239 WeakPolarHBondContact O-CB 3.44Å; V235-S239 PolarHBondContact O-N 2.85Å; V235-S239 PolarHBondContact O-OG 2.84Å
236	F	97.2	Very high	93.2	Very high	0 Å²	0	55.7 Å²	55.7	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-61.1	-50.2	174.5	-92.3	-91.8	0	0	0	111.1	L43 P47 Q107 I110 M114 W232 A233 I234 T238 S239 T240	L43-F236 HydrophobicContact CB-CE1 4Å; L43-F236 HydrophobicContact CB-CE2 4.26Å; L43-F236 HydrophobicContact CB-CZ 3.73Å; L43-F236 HydrophobicContact CD2-CD2 4.17Å; L43-F236 HydrophobicContact CD2-CE2 3.93Å; L43-F236 HydrophobicContact CD2-CZ 4.25Å; L43-F236 HydrophobicContact CG-CZ 4.48Å; L43-F236 VanDerWaalsContact O-CZ 3.26Å; L43-F236 WeakPolarHBondContact O-CZ 3.48Å; P47-F236 HydrophobicContact CG-CZ 4.36Å; Q107-F236 HydrophobicContact CB-CD1 4.13Å; Q107-F236 HydrophobicContact CG-CD1 4.44Å; Q107-F236 HydrophobicContact CG-CE1 4.48Å; I110-F236 HydrophobicContact CB-CD1 4.12Å; I110-F236 HydrophobicContact CB-CE1 3.91Å; I110-F236 HydrophobicContact CB-CZ 4.47Å; I110-F236 HydrophobicContact CD1-CE1 4.25Å; I110-F236 HydrophobicContact CG2-CD1 3.86Å; I110-F236 HydrophobicContact CG2-CD2 4.44Å; I110-F236 HydrophobicContact CG2-CE1 3.38Å; I110-F236 HydrophobicContact CG2-CE2 4.05Å; I110-F236 HydrophobicContact CG2-CG 4.34Å; I110-F236 HydrophobicContact CG2-CZ 3.47Å; I110-F236 VanDerWaalsContact CG2-CZ 3.47Å; M114-F236 HydrophobicContact CE-CD2 4.12Å; M114-F236 HydrophobicContact CE-CE2 3.5Å; M114-F236 HydrophobicContact CE-CZ 4.07Å; M114-F236 HydrophobicContact SD-CD2 3.76Å; M114-F236 HydrophobicContact SD-CE2 3.78Å; W232-F236 VanDerWaalsContact O-CD2 3.32Å; W232-F236 WeakPolarHBondContact O-CD2 3.49Å; W232-F236 PolarHBondContact O-N 3.36Å; A233-F236 PolarHBondContact O-N 2.77Å; I234-F236 VanDerWaalsContact C-N 3.32Å; I234-F236 PolarHBondContact O-N 3.41Å; F236-T238 PolarHBondContact O-N 3.25Å; F236-S239 PolarHBondContact O-OG 3.35Å; F236-S239 VanDerWaalsContact O-OG 3.08Å; F236-T240 WeakPolarHBondContact O-CB 3.31Å; F236-T240 PolarHBondContact O-N 3.21Å; F236-T240 PolarHBondContact O-OG1 3.48Å
237	F	97.6	Very high	93.6	Very high	64 Å²	64	57.1 Å²	57.1	28%	0.281	28%	0.275	S	S	.	.	H	α-helix	trans	-59.6	-46.8	178.8	-74.8	-61.5	0	0	0	112.3	Y108 L112 L115 A233 I234 T241	Y108-F237 AromaticContact CD1-CD1 3.43Å; Y108-F237 HydrophobicContact CD1-CD1 3.43Å; Y108-F237 VanDerWaalsContact CD1-CD1 3.43Å; Y108-F237 AromaticContact CD1-CE1 3.86Å; Y108-F237 HydrophobicContact CD1-CE1 3.86Å; Y108-F237 AromaticContact CE1-CD1 3.81Å; Y108-F237 HydrophobicContact CE1-CD1 3.81Å; L112-F237 HydrophobicContact CB-CZ 4.21Å; L115-F237 HydrophobicContact CD2-CE2 4.33Å; A233-F237 HydrophobicContact CB-CE2 4.36Å; A233-F237 WeakPolarHBondContact O-CD2 3.34Å; A233-F237 PolarHBondContact O-N 3.29Å; I234-F237 PolarHBondContact O-N 3.26Å; F237-T241 WeakPolarHBondContact O-CB 3.37Å; F237-T241 PolarHBondContact O-N 2.9Å; F237-T241 PolarHBondContact O-OG1 3.2Å
238	T	97.4	Very high	93.6	Very high	74 Å²	74	54.2 Å²	54.2	45%	0.454	27%	0.274	S	S	.	.	H	α-helix	trans	-65.9	-52.2	-178.3	-54	0	0	0	0	110.5	I234 F236 T240 T241 L242	I234-T238 VanDerWaalsContact O-CB 3.28Å; I234-T238 WeakPolarHBondContact O-CB 3.37Å; I234-T238 PolarHBondContact O-N 3.16Å; I234-T238 PolarHBondContact O-OG1 3.04Å; F236-T238 PolarHBondContact O-N 3.25Å; T238-T240 PolarHBondContact O-N 2.87Å; T238-T241 PolarHBondContact O-N 3.34Å; T238-L242 HydrophobicContact CG2-CD1 4.2Å; T238-L242 VanDerWaalsContact O-CG 3.31Å; T238-L242 WeakPolarHBondContact O-CG 3.36Å; T238-L242 PolarHBondContact O-N 2.96Å
239	S	96.2	Very high	93.4	Very high	9 Å²	9	54.6 Å²	54.6	6%	0.063	28%	0.277	C	S	.	.	H	α-helix	trans	-61.7	-42.6	-179.8	57.5	0	0	0	0	112.9	L43 V235 F236 T241 L242 V243	L43-S239 WeakPolarHBondContact CD1-OG 3.48Å; V235-S239 WeakPolarHBondContact O-CB 3.44Å; V235-S239 PolarHBondContact O-N 2.85Å; V235-S239 PolarHBondContact O-OG 2.84Å; F236-S239 PolarHBondContact O-OG 3.35Å; F236-S239 VanDerWaalsContact O-OG 3.08Å; S239-T241 VanDerWaalsContact C-N 3.3Å; S239-T241 PolarHBondContact O-N 2.95Å; S239-L242 PolarHBondContact O-N 3.09Å; S239-V243 WeakPolarHBondContact O-CG2 3.42Å; S239-V243 PolarHBondContact O-N 3.05Å
240	T	96.5	Very high	92.3	Very high	0 Å²	0	61.7 Å²	61.7	0%	0	32%	0.315	C	S	.	.	H	α-helix	trans	-60.4	-43.6	177.1	-55.1	0	0	0	0	110.6	I104 Q107 Y108 F236 T238 V243 L244	I104-T240 HydrophobicContact CB-CG2 4.22Å; I104-T240 HydrophobicContact CD1-CG2 3.67Å; I104-T240 WeakPolarHBondContact CD1-O 3.33Å; I104-T240 HydrophobicContact CG2-CG2 3.83Å; Q107-T240 HydrophobicContact CB-CG2 4.04Å; Q107-T240 WeakPolarHBondContact CB-OG1 3.3Å; Q107-T240 PolarHBondContact OE1-OG1 3.46Å; Y108-T240 HydrophobicContact CD1-CG2 3.85Å; Y108-T240 HydrophobicContact CD2-CG2 3.68Å; Y108-T240 HydrophobicContact CE1-CG2 3.74Å; Y108-T240 HydrophobicContact CE2-CG2 3.55Å; Y108-T240 HydrophobicContact CG-CG2 3.84Å; F236-T240 WeakPolarHBondContact O-CB 3.31Å; F236-T240 PolarHBondContact O-N 3.21Å; F236-T240 PolarHBondContact O-OG1 3.48Å; T238-T240 PolarHBondContact O-N 2.87Å; T240-V243 PolarHBondContact O-N 2.83Å; T240-L244 WeakPolarHBondContact O-CB 3.4Å; T240-L244 PolarHBondContact O-N 3.32Å
241	T	96.3	Very high	90.9	Very high	52 Å²	52	58.6 Å²	58.6	32%	0.319	32%	0.319	S	S	.	.	H	α-helix	trans	-65.3	-41.6	177.5	-52.3	0	0	0	0	111.5	Y108 F237 T238 S239 V243 L244 L245	Y108-T241 WeakPolarHBondContact OH-CA 3.48Å; Y108-T241 PolarHBondContact OH-OG1 3.47Å; F237-T241 WeakPolarHBondContact O-CB 3.37Å; F237-T241 PolarHBondContact O-N 2.9Å; F237-T241 PolarHBondContact O-OG1 3.2Å; T238-T241 PolarHBondContact O-N 3.34Å; S239-T241 VanDerWaalsContact C-N 3.3Å; S239-T241 PolarHBondContact O-N 2.95Å; T241-V243 PolarHBondContact O-N 3.4Å; T241-L244 WeakPolarHBondContact O-CB 3.45Å; T241-L244 PolarHBondContact O-N 2.93Å; T241-L245 HydrophobicContact CG2-CD1 4Å; T241-L245 HydrophobicContact CG2-CG 4.42Å; T241-L245 VanDerWaalsContact O-CG 3.29Å; T241-L245 WeakPolarHBondContact O-CG 3.44Å; T241-L245 PolarHBondContact O-N 3.32Å
242	L	96	Very high	89	Confident	89 Å²	89	55.8 Å²	55.8	47%	0.466	31%	0.308	S	S	.	.	H	α-helix	trans	-62.7	-42.7	175.6	-67.7	174.7	0	0	0	111.8	T238 S239 L244 L245 F246	T238-L242 HydrophobicContact CG2-CD1 4.2Å; T238-L242 VanDerWaalsContact O-CG 3.31Å; T238-L242 WeakPolarHBondContact O-CG 3.36Å; T238-L242 PolarHBondContact O-N 2.96Å; S239-L242 PolarHBondContact O-N 3.09Å; L242-L244 VanDerWaalsContact C-N 3.35Å; L242-L245 PolarHBondContact O-N 3.29Å; L242-F246 HydrophobicContact CB-CD2 4.37Å; L242-F246 HydrophobicContact CD2-CD2 3.96Å; L242-F246 HydrophobicContact CD2-CE2 3.65Å; L242-F246 WeakPolarHBondContact O-CB 3.41Å; L242-F246 WeakPolarHBondContact O-CD2 3.3Å; L242-F246 PolarHBondContact O-N 3.12Å
243	V	94.6	Very high	87	Confident	9 Å²	9	62.3 Å²	62.3	6%	0.055	34%	0.339	C	S	.	.	H	α-helix	trans	-63.7	-42.4	175.8	173.7	0	0	0	0	110.8	L36 L103 I104 W161 S239 T240 T241 L245 K247	L36-V243 HydrophobicContact CD1-CG2 3.93Å; L103-V243 HydrophobicContact CD2-CG1 4.22Å; I104-V243 HydrophobicContact CD1-CB 4.26Å; I104-V243 HydrophobicContact CD1-CG1 4.06Å; W161-V243 HydrophobicContact CH2-CG1 3.73Å; W161-V243 HydrophobicContact CZ3-CG1 4.03Å; S239-V243 WeakPolarHBondContact O-CG2 3.42Å; S239-V243 PolarHBondContact O-N 3.05Å; T240-V243 PolarHBondContact O-N 2.83Å; T241-V243 PolarHBondContact O-N 3.4Å; V243-L245 VanDerWaalsContact C-N 3.33Å; V243-L245 PolarHBondContact O-N 3.43Å; V243-K247 HydrophobicContact CG1-CB 4.14Å; V243-K247 VanDerWaalsContact O-CB 3.28Å; V243-K247 WeakPolarHBondContact O-CB 3.26Å; V243-K247 PolarHBondContact O-N 3.49Å; V243-K247 VanDerWaalsContact O-N 3.07Å
244	L	93.1	Very high	85.3	Confident	58 Å²	58	64.5 Å²	64.5	30%	0.304	36%	0.357	S	S	.	.	H	α-helix	trans	-59.3	-43.2	177.2	177.8	62.5	0	0	0	112.1	I104 T240 T241 L242	I104-L244 HydrophobicContact CD1-CB 4.01Å; I104-L244 HydrophobicContact CG1-CB 4.48Å; I104-L244 HydrophobicContact CG1-CD1 4.36Å; T240-L244 WeakPolarHBondContact O-CB 3.4Å; T240-L244 PolarHBondContact O-N 3.32Å; T241-L244 WeakPolarHBondContact O-CB 3.45Å; T241-L244 PolarHBondContact O-N 2.93Å; L242-L244 VanDerWaalsContact C-N 3.35Å
245	L	92.7	Very high	83.8	Confident	121 Å²	121	62.4 Å²	62.4	63%	0.634	35%	0.345	S	S	*	.	H	α-helix	trans	-81.9	-42	-175	-66.4	176.7	0	0	0	113.4	T241 L242 V243	T241-L245 HydrophobicContact CG2-CD1 4Å; T241-L245 HydrophobicContact CG2-CG 4.42Å; T241-L245 VanDerWaalsContact O-CG 3.29Å; T241-L245 WeakPolarHBondContact O-CG 3.44Å; T241-L245 PolarHBondContact O-N 3.32Å; L242-L245 PolarHBondContact O-N 3.29Å; V243-L245 VanDerWaalsContact C-N 3.33Å; V243-L245 PolarHBondContact O-N 3.43Å
246	F	91.6	Very high	82.1	Confident	165 Å²	165	62.2 Å²	62.2	72%	0.724	35%	0.346	S	S	*	.	H	α-helix	trans	-104.1	-20.5	-168.1	-64.6	-70.3	0	0	0	114.2	L242	L242-F246 HydrophobicContact CB-CD2 4.37Å; L242-F246 HydrophobicContact CD2-CD2 3.96Å; L242-F246 HydrophobicContact CD2-CE2 3.65Å; L242-F246 WeakPolarHBondContact O-CB 3.41Å; L242-F246 WeakPolarHBondContact O-CD2 3.3Å; L242-F246 PolarHBondContact O-N 3.12Å
247	K	89.9	Confident	80.6	Confident	44 Å²	44	68.1 Å²	68.1	19%	0.191	38%	0.378	C	S	.	.			trans	-96.4	108	-177.8	-170.3	61	179.3	176.4	0	111.6	N33 L36 K100 W161 V243	N33-K247 PolarHBondContact OD1-NZ 3.1Å; L36-K247 HydrophobicContact CD2-CD 4.11Å; L36-K247 HydrophobicContact CD2-CG 4.22Å; K100-K247 WeakPolarHBondContact CE-O 3.24Å; K100-K247 PolarHBondContact NZ-O 3.14Å; K100-K247 VanDerWaalsContact NZ-O 3.08Å; W161-K247 HydrophobicContact CH2-CB 4.29Å; W161-K247 HydrophobicContact CH2-CG 3.53Å; W161-K247 HydrophobicContact CZ2-CD 4.37Å; W161-K247 HydrophobicContact CZ2-CG 3.45Å; W161-K247 VanDerWaalsContact CZ2-CG 3.45Å; V243-K247 HydrophobicContact CG1-CB 4.14Å; V243-K247 VanDerWaalsContact O-CB 3.28Å; V243-K247 WeakPolarHBondContact O-CB 3.26Å; V243-K247 PolarHBondContact O-N 3.49Å; V243-K247 VanDerWaalsContact O-N 3.07Å
248	A	85.1	Confident	79.2	Confident	66 Å²	66	65.4 Å²	65.4	55%	0.545	37%	0.366	S	S	.	.			trans	-78.1	148.2	167.8	0	0	0	0	0	111.5
249	E	82.6	Confident	78.1	Confident	38 Å²	38	69.4 Å²	69.4	18%	0.178	37%	0.373	C	S	.	.			trans	-106.5	135.3	168.2	-78.5	-177.6	-124.6	0	0	108.7	G97 R98 R99 K100 W161	G97-E249 WeakPolarHBondContact CA-OE1 3.38Å; R98-E249 PolarHBondContact N-OE2 2.97Å; R99-E249 PolarHBondContact N-OE1 3.21Å; R99-E249 PolarHBondContact N-OE2 3.19Å; K100-E249 WeakPolarHBondContact CB-OE1 3.32Å; K100-E249 WeakPolarHBondContact CE-OE1 3.33Å; K100-E249 WeakPolarHBondContact CG-OE1 3.39Å; K100-E249 PolarHBondContact N-OE1 3.33Å; W161-E249 HydrophobicContact CZ2-CG 4.22Å
250	N	66.6	Low	77.6	Confident	157 Å²	157	71.3 Å²	71.3	84%	0.84	39%	0.386	S	S	*	.			trans	-108.8	145.4	178.1	-66	-22	0	0	0	110
251	G	60.9	Low	77.2	Confident	53 Å²	53	73.7 Å²	73.7	55%	0.546	40%	0.401	S	S	.	.			trans	95.8	29.3	159.6	0	0	0	0	0	117.9	H253 F255	G251-H253 PolarHBondContact O-N 3.44Å; G251-F255 WeakPolarHBondContact O-CD2 3.3Å; G251-F255 WeakPolarHBondContact O-CE2 3.42Å
252	E	53.3	Low	76.9	Confident	55 Å²	55	74.8 Å²	74.8	26%	0.257	41%	0.411	S	S	.	.	G	3₁₀ helix	trans	-67.4	-28.7	-171.7	-61.7	-177.9	168	0	0	115.8	M94 G97 A254 F255	M94-E252 HydrophobicContact CE-CB 3.77Å; G97-E252 VanDerWaalsContact CA-OE1 3.3Å; G97-E252 WeakPolarHBondContact CA-OE1 3.48Å; E252-A254 PolarHBondContact O-N 3.32Å; E252-A254 VanDerWaalsContact O-N 3.16Å; E252-F255 PolarHBondContact O-N 2.88Å
253	H	51.8	Low	76.6	Confident	154 Å²	154	76.1 Å²	76.1	71%	0.713	41%	0.413	S	S	*	.	G	3₁₀ helix	trans	-60.9	-27.5	-176.7	-70.6	-58.4	0	0	0	113.2	G251 F255	G251-H253 PolarHBondContact O-N 3.44Å; H253-F255 PolarHBondContact O-N 3.38Å
254	A	59	Low	76.3	Confident	47 Å²	47	75.7 Å²	75.7	39%	0.388	41%	0.41	S	S	.	.	G	3₁₀ helix	trans	-70.1	-13	178	0	0	0	0	0	113.8	E252	E252-A254 PolarHBondContact O-N 3.32Å; E252-A254 VanDerWaalsContact O-N 3.16Å
255	F	64.8	Low	76.3	Confident	27 Å²	27	77.1 Å²	77.1	12%	0.118	41%	0.412	C	S	.	.	G	3₁₀ helix	trans	-116.4	1.7	-172.8	-51.3	-66.6	0	0	0	113.9	R98 G251 E252 H253 D257 M258 V411	R98-F255 VanDerWaalsContact NH2-CD1 3.26Å; G251-F255 WeakPolarHBondContact O-CD2 3.3Å; G251-F255 WeakPolarHBondContact O-CE2 3.42Å; E252-F255 PolarHBondContact O-N 2.88Å; H253-F255 PolarHBondContact O-N 3.38Å; F255-D257 PolarHBondContact O-N 2.98Å; F255-D257 VanDerWaalsContact O-N 3.1Å; F255-M258 PolarHBondContact O-N 3.38Å; F255-M258 VanDerWaalsContact O-N 3.08Å; F255-V411 HydrophobicContact CD1-CB 4.24Å; F255-V411 HydrophobicContact CD1-CG1 4.25Å; F255-V411 HydrophobicContact CD1-CG2 4.04Å; F255-V411 HydrophobicContact CE1-CB 4.21Å; F255-V411 HydrophobicContact CE1-CG2 3.79Å
256	A	61.5	Low	76.2	Confident	24 Å²	24	78.3 Å²	78.3	20%	0.198	41%	0.408	C	S	.	.	G	3₁₀ helix	trans	-59.3	-25.6	-176.1	0	0	0	0	0	113.4	M258 R259	A256-M258 VanDerWaalsContact C-N 3.33Å; A256-R259 WeakPolarHBondContact O-CG 3.49Å; A256-R259 PolarHBondContact O-NE 3.25Å
257	D	65.4	Low	76.1	Confident	125 Å²	125	71.5 Å²	71.5	67%	0.668	38%	0.379	S	S	*	.	G	3₁₀ helix	trans	-75.5	-18.4	-179.6	-70	-23.3	0	0	0	114.1	F255 R259	F255-D257 PolarHBondContact O-N 2.98Å; F255-D257 VanDerWaalsContact O-N 3.1Å; D257-R259 VanDerWaalsContact C-N 3.3Å; D257-R259 PolarHBondContact O-N 3.23Å
258	M	67.1	Low	76.2	Confident	7 Å²	7	70 Å²	70	3%	0.034	37%	0.373	C	S	.	.	G	3₁₀ helix	trans	-87.9	10.4	-176	-74.1	-59.5	-65.1	0	0	114.7	S90 F255 A256 S260 T264 Q267 V411 V412	S90-M258 VanDerWaalsContact CA-O 3.29Å; S90-M258 WeakPolarHBondContact CA-O 3.46Å; S90-M258 WeakPolarHBondContact CB-O 3.49Å; F255-M258 PolarHBondContact O-N 3.38Å; F255-M258 VanDerWaalsContact O-N 3.08Å; A256-M258 VanDerWaalsContact C-N 3.33Å; M258-S260 PolarHBondContact O-N 2.99Å; M258-S260 VanDerWaalsContact O-N 3.08Å; M258-T264 HydrophobicContact CE-CG2 3.68Å; M258-T264 WeakPolarHBondContact CE-OG1 3.41Å; M258-Q267 PolarHBondContact SD-NE2 3.38Å; M258-Q267 PolarHBondContact SD-OE1 3.02Å; M258-V411 HydrophobicContact CG-CG1 3.52Å; M258-V411 HydrophobicContact SD-CG1 4.28Å; M258-V412 HydrophobicContact CE-CG1 3.23Å; M258-V412 HydrophobicContact SD-CG1 4.49Å
259	R	74.1	Confident	76.5	Confident	157 Å²	157	71.9 Å²	71.9	59%	0.592	37%	0.373	S	S	*	.	G	3₁₀ helix	trans	-67.2	-8	-179.8	-73.2	-174.8	-79.5	179.7	-5	115.2	S90 F92 A256 D257	S90-R259 WeakPolarHBondContact O-CA 3.42Å; F92-R259 HydrophobicContact CE1-CG 4.43Å; F92-R259 HydrophobicContact CZ-CG 4.44Å; A256-R259 WeakPolarHBondContact O-CG 3.49Å; A256-R259 PolarHBondContact O-NE 3.25Å; D257-R259 VanDerWaalsContact C-N 3.3Å; D257-R259 PolarHBondContact O-N 3.23Å
260	S	85.5	Confident	77	Confident	49 Å²	49	76.7 Å²	76.7	34%	0.343	39%	0.39	S	S	.	.			trans	-98.9	112.9	178.3	-178.7	0	0	0	0	111.1	M258 S262 K263 T264	M258-S260 PolarHBondContact O-N 2.99Å; M258-S260 VanDerWaalsContact O-N 3.08Å; S260-S262 PolarHBondContact O-N 2.9Å; S260-K263 WeakPolarHBondContact O-CA 3.32Å; S260-K263 WeakPolarHBondContact O-CB 3.46Å; S260-K263 PolarHBondContact O-N 3.04Å; S260-T264 PolarHBondContact O-N 3.18Å; S260-T264 VanDerWaalsContact O-N 3.14Å; S260-T264 PolarHBondContact O-OG1 3.42Å
261	V	90	Very high	78.3	Confident	50 Å²	50	69.2 Å²	69.2	30%	0.303	35%	0.35	S	S	.	.	H	α-helix	trans	-49.1	-45.1	174.6	178.3	0	0	0	0	111.5	V87 S90 V91 K263 T264 Y265	V87-V261 HydrophobicContact CG2-CG1 4.08Å; S90-V261 WeakPolarHBondContact OG-CA 3.34Å; S90-V261 WeakPolarHBondContact OG-CG2 3.2Å; V91-V261 HydrophobicContact CG2-CG2 3.75Å; V261-K263 VanDerWaalsContact C-N 3.33Å; V261-K263 PolarHBondContact O-N 3.1Å; V261-T264 PolarHBondContact O-N 2.86Å; V261-T264 VanDerWaalsContact O-N 3.14Å; V261-Y265 HydrophobicContact CG1-CD2 3.71Å; V261-Y265 HydrophobicContact CG1-CE2 3.45Å; V261-Y265 VanDerWaalsContact CG1-CE2 3.45Å; V261-Y265 VanDerWaalsContact O-CD2 3.27Å; V261-Y265 WeakPolarHBondContact O-CD2 3.25Å; V261-Y265 PolarHBondContact O-N 3.33Å
262	S	89.9	Confident	79.7	Confident	76 Å²	76	69.9 Å²	69.9	53%	0.531	34%	0.339	S	S	.	.	H	α-helix	trans	-61	-39.1	178.5	-177	0	0	0	0	112.7	S260 R266	S260-S262 PolarHBondContact O-N 2.9Å; S262-R266 WeakPolarHBondContact O-CB 3.38Å; S262-R266 PolarHBondContact O-N 3.2Å
263	K	88.4	Confident	81.6	Confident	117 Å²	117	71.7 Å²	71.7	51%	0.509	36%	0.357	S	S	.	.	H	α-helix	trans	-64.6	-41	175.4	-68.3	-175.9	-176.4	-178.7	0	110.9	S260 V261 R266 Q267	S260-K263 WeakPolarHBondContact O-CA 3.32Å; S260-K263 WeakPolarHBondContact O-CB 3.46Å; S260-K263 PolarHBondContact O-N 3.04Å; V261-K263 VanDerWaalsContact C-N 3.33Å; V261-K263 PolarHBondContact O-N 3.1Å; K263-R266 WeakPolarHBondContact O-CB 3.17Å; K263-R266 PolarHBondContact O-N 3.33Å; K263-Q267 WeakPolarHBondContact O-CG 3.27Å; K263-Q267 PolarHBondContact O-N 2.93Å
264	T	89.2	Confident	83.7	Confident	0 Å²	0	66 Å²	66	0%	0	33%	0.332	C	S	.	.	H	α-helix	trans	-65.6	-43.2	178.9	-43.6	0	0	0	0	112.6	P86 D89 S90 M258 S260 V261 R266 Q267 L268 V412	P86-T264 HydrophobicContact CB-CG2 3.73Å; D89-T264 HydrophobicContact CB-CG2 4.27Å; S90-T264 WeakPolarHBondContact CB-OG1 3.16Å; M258-T264 HydrophobicContact CE-CG2 3.68Å; M258-T264 WeakPolarHBondContact CE-OG1 3.41Å; S260-T264 PolarHBondContact O-N 3.18Å; S260-T264 VanDerWaalsContact O-N 3.14Å; S260-T264 PolarHBondContact O-OG1 3.42Å; V261-T264 PolarHBondContact O-N 2.86Å; V261-T264 VanDerWaalsContact O-N 3.14Å; T264-R266 VanDerWaalsContact C-N 3.33Å; T264-R266 PolarHBondContact O-N 3.07Å; T264-Q267 WeakPolarHBondContact O-CB 3.47Å; T264-Q267 PolarHBondContact O-N 3.02Å; T264-L268 PolarHBondContact O-N 3.32Å; T264-V412 HydrophobicContact CG2-CG1 3.96Å
265	Y	92.6	Very high	85.4	Confident	88 Å²	88	72.4 Å²	72.4	35%	0.345	35%	0.351	S	S	.	.	H	α-helix	trans	-62.6	-40.7	172.2	-80.1	-77.3	0	0	0	112.1	L83 P86 V87 V261 Q267 L268 L269	L83-Y265 PolarHBondContact O-OH 2.76Å; P86-Y265 HydrophobicContact CB-CD1 4.1Å; P86-Y265 HydrophobicContact CB-CD2 4.01Å; P86-Y265 HydrophobicContact CB-CE1 3.99Å; P86-Y265 HydrophobicContact CB-CE2 3.91Å; P86-Y265 HydrophobicContact CB-CG 4.1Å; P86-Y265 HydrophobicContact CG-CD1 3.85Å; P86-Y265 HydrophobicContact CG-CE1 3.66Å; P86-Y265 HydrophobicContact CG-CE2 4.49Å; P86-Y265 HydrophobicContact CG-CG 4.34Å; V87-Y265 HydrophobicContact CG2-CE2 4.32Å; V261-Y265 HydrophobicContact CG1-CD2 3.71Å; V261-Y265 HydrophobicContact CG1-CE2 3.45Å; V261-Y265 VanDerWaalsContact CG1-CE2 3.45Å; V261-Y265 VanDerWaalsContact O-CD2 3.27Å; V261-Y265 WeakPolarHBondContact O-CD2 3.25Å; V261-Y265 PolarHBondContact O-N 3.33Å; Y265-Q267 VanDerWaalsContact C-N 3.27Å; Y265-Q267 PolarHBondContact O-N 3.43Å; Y265-L268 HydrophobicContact CD1-CD2 4.47Å; Y265-L268 WeakPolarHBondContact O-CB 3.25Å; Y265-L268 PolarHBondContact O-N 3.37Å; Y265-L269 WeakPolarHBondContact O-CG 3.13Å; Y265-L269 PolarHBondContact O-N 3.31Å
266	R	91.6	Very high	86.9	Confident	145 Å²	145	71.9 Å²	71.9	55%	0.547	35%	0.35	S	S	.	.	H	α-helix	trans	-62.3	-37.1	175.2	-170.8	-179.2	-62.8	-91.9	1.4	111.6	S262 K263 T264 L269 R270	S262-R266 WeakPolarHBondContact O-CB 3.38Å; S262-R266 PolarHBondContact O-N 3.2Å; K263-R266 WeakPolarHBondContact O-CB 3.17Å; K263-R266 PolarHBondContact O-N 3.33Å; T264-R266 VanDerWaalsContact C-N 3.33Å; T264-R266 PolarHBondContact O-N 3.07Å; R266-L269 PolarHBondContact O-N 2.9Å; R266-R270 WeakPolarHBondContact O-CG 3.38Å; R266-R270 PolarHBondContact O-N 3.29Å
267	Q	89.3	Confident	88.5	Confident	22 Å²	22	70.7 Å²	70.7	10%	0.103	34%	0.341	C	S	.	.	H	α-helix	trans	-67.6	-41.7	173.7	-75.8	-175.1	-3.3	0	0	112.3	M258 K263 T264 Y265 L269 R270 I271	M258-Q267 PolarHBondContact SD-NE2 3.38Å; M258-Q267 PolarHBondContact SD-OE1 3.02Å; K263-Q267 WeakPolarHBondContact O-CG 3.27Å; K263-Q267 PolarHBondContact O-N 2.93Å; T264-Q267 WeakPolarHBondContact O-CB 3.47Å; T264-Q267 PolarHBondContact O-N 3.02Å; Y265-Q267 VanDerWaalsContact C-N 3.27Å; Y265-Q267 PolarHBondContact O-N 3.43Å; Q267-L269 VanDerWaalsContact C-N 3.31Å; Q267-L269 PolarHBondContact O-N 3.41Å; Q267-R270 WeakPolarHBondContact O-CB 3.12Å; Q267-R270 PolarHBondContact O-N 2.89Å; Q267-R270 VanDerWaalsContact O-N 3.09Å; Q267-I271 WeakPolarHBondContact O-CG1 3.45Å; Q267-I271 PolarHBondContact O-N 2.67Å
268	L	91.8	Very high	89.9	Confident	14 Å²	14	68.4 Å²	68.4	7%	0.073	33%	0.328	C	S	.	.	H	α-helix	trans	-54.8	-47.6	172.5	170.2	60.3	0	0	0	111.3	L82 P86 T264 Y265 R270 I271 M272 T415 L419	L82-L268 HydrophobicContact CD1-CD1 4.06Å; L82-L268 HydrophobicContact CD1-CD2 4.05Å; P86-L268 HydrophobicContact CG-CD2 3.96Å; T264-L268 PolarHBondContact O-N 3.32Å; Y265-L268 HydrophobicContact CD1-CD2 4.47Å; Y265-L268 WeakPolarHBondContact O-CB 3.25Å; Y265-L268 PolarHBondContact O-N 3.37Å; L268-R270 VanDerWaalsContact C-N 3.33Å; L268-R270 PolarHBondContact O-N 3.5Å; L268-I271 PolarHBondContact O-N 2.89Å; L268-M272 WeakPolarHBondContact O-CG 3.29Å; L268-M272 PolarHBondContact O-N 3.22Å; L268-M272 VanDerWaalsContact O-N 3.1Å; L268-T415 HydrophobicContact CB-CG2 3.89Å; L268-T415 HydrophobicContact CD1-CG2 3.78Å; L268-T415 HydrophobicContact CD2-CG2 4.14Å; L268-T415 HydrophobicContact CG-CG2 4.14Å; L268-L419 HydrophobicContact CD1-CB 4.14Å; L268-L419 HydrophobicContact CD1-CD1 4.08Å; L268-L419 HydrophobicContact CD1-CD2 3.77Å; L268-L419 HydrophobicContact CD1-CG 4.19Å
269	L	92.1	Very high	91.3	Very high	105 Å²	105	69.5 Å²	69.5	55%	0.55	34%	0.337	S	S	.	.	H	α-helix	trans	-59.6	-42.8	175.4	-66.3	176	0	0	0	111.8	Y265 R266 Q267 M272 C273	Y265-L269 WeakPolarHBondContact O-CG 3.13Å; Y265-L269 PolarHBondContact O-N 3.31Å; R266-L269 PolarHBondContact O-N 2.9Å; Q267-L269 VanDerWaalsContact C-N 3.31Å; Q267-L269 PolarHBondContact O-N 3.41Å; L269-M272 HydrophobicContact CD2-CE 3.55Å; L269-M272 PolarHBondContact O-N 3.06Å; L269-C273 PolarHBondContact O-N 3.07Å; L269-C273 PolarHBondContact O-SG 3.05Å
270	R	92.1	Very high	92.4	Very high	138 Å²	138	62 Å²	62	52%	0.521	31%	0.309	S	S	.	.	H	α-helix	trans	-63.8	-41	176.6	-73.3	174.9	-179	178.6	-0.3	112.5	R266 Q267 L268 M272 C273 L274 P497	R266-R270 WeakPolarHBondContact O-CG 3.38Å; R266-R270 PolarHBondContact O-N 3.29Å; Q267-R270 WeakPolarHBondContact O-CB 3.12Å; Q267-R270 PolarHBondContact O-N 2.89Å; Q267-R270 VanDerWaalsContact O-N 3.09Å; L268-R270 VanDerWaalsContact C-N 3.33Å; L268-R270 PolarHBondContact O-N 3.5Å; R270-M272 VanDerWaalsContact C-N 3.33Å; R270-M272 PolarHBondContact O-N 3.42Å; R270-C273 WeakPolarHBondContact O-CA 3.33Å; R270-C273 WeakPolarHBondContact O-CB 3.43Å; R270-C273 PolarHBondContact O-N 3.48Å; R270-L274 PolarHBondContact O-N 2.76Å; R270-P497 HydrophobicContact CB-CB 4.45Å
271	I	92.9	Very high	92.8	Very high	0 Å²	0	61 Å²	61	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-60.2	-44.9	177.9	-72	161.4	0	0	0	110.2	Q267 L268 C273 L274 V277 V412 Y416 L419 P497	Q267-I271 WeakPolarHBondContact O-CG1 3.45Å; Q267-I271 PolarHBondContact O-N 2.67Å; L268-I271 PolarHBondContact O-N 2.89Å; I271-C273 PolarHBondContact O-N 2.63Å; I271-C273 VanDerWaalsContact O-N 3.17Å; I271-L274 WeakPolarHBondContact O-CB 3.39Å; I271-L274 PolarHBondContact O-N 3.34Å; I271-V277 HydrophobicContact CG2-CG2 4.23Å; I271-V277 WeakPolarHBondContact O-CB 3.42Å; I271-V277 WeakPolarHBondContact O-CG1 3.36Å; I271-V412 HydrophobicContact CD1-CG2 3.66Å; I271-Y416 HydrophobicContact CB-CE2 4.41Å; I271-Y416 HydrophobicContact CD1-CD2 3.56Å; I271-Y416 HydrophobicContact CD1-CE2 3.89Å; I271-Y416 HydrophobicContact CD1-CG 4.27Å; I271-Y416 HydrophobicContact CG1-CD2 4.11Å; I271-Y416 HydrophobicContact CG1-CE2 3.9Å; I271-Y416 HydrophobicContact CG2-CD1 4.2Å; I271-Y416 HydrophobicContact CG2-CD2 3.99Å; I271-Y416 HydrophobicContact CG2-CE1 3.77Å; I271-Y416 HydrophobicContact CG2-CE2 3.58Å; I271-Y416 HydrophobicContact CG2-CG 4.28Å; I271-Y416 VanDerWaalsContact CG2-CZ 3.45Å; I271-L419 HydrophobicContact CG2-CD2 3.77Å; I271-P497 HydrophobicContact CD1-CG 4.39Å; I271-P497 HydrophobicContact CG1-CG 3.99Å
272	M	91.8	Very high	93.1	Very high	67 Å²	67	62.1 Å²	62.1	33%	0.33	31%	0.309	S	S	.	.	H	α-helix	trans	-61.3	-24.1	176.1	-69.2	-169.3	-62.6	0	0	113.2	L268 L269 R270 I278 L419	L268-M272 WeakPolarHBondContact O-CG 3.29Å; L268-M272 PolarHBondContact O-N 3.22Å; L268-M272 VanDerWaalsContact O-N 3.1Å; L269-M272 HydrophobicContact CD2-CE 3.55Å; L269-M272 PolarHBondContact O-N 3.06Å; R270-M272 VanDerWaalsContact C-N 3.33Å; R270-M272 PolarHBondContact O-N 3.42Å; M272-I278 VanDerWaalsContact O-CG1 3.24Å; M272-I278 WeakPolarHBondContact O-CG1 3.44Å; M272-L419 HydrophobicContact CG-CD1 3.89Å; M272-L419 HydrophobicContact CG-CD2 3.68Å; M272-L419 HydrophobicContact CG-CG 4.41Å; M272-L419 HydrophobicContact SD-CD1 3.85Å
273	C	93.3	Very high	93.5	Very high	94 Å²	94	58.8 Å²	58.8	64%	0.635	29%	0.285	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.3	-5.2	176.9	-62.5	0	0	0	0	114.1	L269 R270 I271 K275	L269-C273 PolarHBondContact O-N 3.07Å; L269-C273 PolarHBondContact O-SG 3.05Å; R270-C273 WeakPolarHBondContact O-CA 3.33Å; R270-C273 WeakPolarHBondContact O-CB 3.43Å; R270-C273 PolarHBondContact O-N 3.48Å; I271-C273 PolarHBondContact O-N 2.63Å; I271-C273 VanDerWaalsContact O-N 3.17Å; C273-K275 PolarHBondContact O-N 3.12Å
274	L	94.3	Very high	93.8	Very high	35 Å²	35	53.5 Å²	53.5	18%	0.183	26%	0.262	C	S	.	.			trans	-68.1	129.4	178.2	-66.4	174.8	0	0	0	110.1	R270 I271 P276 V277 I278 W495	R270-L274 PolarHBondContact O-N 2.76Å; I271-L274 WeakPolarHBondContact O-CB 3.39Å; I271-L274 PolarHBondContact O-N 3.34Å; L274-P276 HydrophobicContact CB-CG 4.43Å; L274-V277 HydrophobicContact CB-CB 4.1Å; L274-V277 HydrophobicContact CB-CG2 3.85Å; L274-V277 HydrophobicContact CD1-CG2 4.26Å; L274-V277 WeakPolarHBondContact O-CA 3.43Å; L274-V277 WeakPolarHBondContact O-CB 3.41Å; L274-V277 PolarHBondContact O-N 3.41Å; L274-I278 WeakPolarHBondContact O-CG1 3.38Å; L274-I278 PolarHBondContact O-N 2.92Å; L274-W495 WeakPolarHBondContact CD1-O 3.47Å
275	K	95.2	Very high	94.1	Very high	180 Å²	180	55.9 Å²	55.9	78%	0.783	28%	0.275	S	S	*	.	H	α-helix	trans	-48.2	-48.6	178.4	-66.3	-177.5	179.9	178.5	0	114.1	C273 V277 I278 A279	C273-K275 PolarHBondContact O-N 3.12Å; K275-V277 VanDerWaalsContact C-N 3.33Å; K275-V277 PolarHBondContact O-N 2.59Å; K275-I278 PolarHBondContact O-N 3.42Å; K275-A279 WeakPolarHBondContact O-CB 3.3Å; K275-A279 PolarHBondContact O-N 3.24Å
276	P	95.7	Very high	94.3	Very high	16 Å²	16	54.1 Å²	54.1	10%	0.104	27%	0.273	C	S	.	.	H	α-helix	trans	-64.8	-35.1	177.2	23.7	-33.4	0	0	0	113.1	L274 A279 L280 L487 V490 S494 W495	L274-P276 HydrophobicContact CB-CG 4.43Å; P276-A279 PolarHBondContact O-N 3.5Å; P276-L280 WeakPolarHBondContact O-CB 3.14Å; P276-L280 PolarHBondContact O-N 3.35Å; P276-L487 HydrophobicContact CB-CD2 4.06Å; P276-V490 HydrophobicContact CB-CG1 4.27Å; P276-V490 HydrophobicContact CG-CG1 4.46Å; P276-S494 VanDerWaalsContact CG-O 3.3Å; P276-S494 WeakPolarHBondContact CG-O 3.08Å; P276-W495 HydrophobicContact CB-CD2 3.99Å; P276-W495 HydrophobicContact CB-CE3 4.08Å; P276-W495 HydrophobicContact CB-CH2 3.78Å; P276-W495 HydrophobicContact CB-CZ2 3.67Å; P276-W495 HydrophobicContact CB-CZ3 3.98Å; P276-W495 HydrophobicContact CG-CD2 4.19Å; P276-W495 HydrophobicContact CG-CE3 4.34Å
277	V	95.4	Very high	94.5	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-67.6	-45.5	176.4	177.4	0	0	0	0	110.8	I271 L274 K275 A279 L280 I281 Y416 L420 W495	I271-V277 HydrophobicContact CG2-CG2 4.23Å; I271-V277 WeakPolarHBondContact O-CB 3.42Å; I271-V277 WeakPolarHBondContact O-CG1 3.36Å; L274-V277 HydrophobicContact CB-CB 4.1Å; L274-V277 HydrophobicContact CB-CG2 3.85Å; L274-V277 HydrophobicContact CD1-CG2 4.26Å; L274-V277 WeakPolarHBondContact O-CA 3.43Å; L274-V277 WeakPolarHBondContact O-CB 3.41Å; L274-V277 PolarHBondContact O-N 3.41Å; K275-V277 VanDerWaalsContact C-N 3.33Å; K275-V277 PolarHBondContact O-N 2.59Å; V277-A279 VanDerWaalsContact C-N 3.34Å; V277-A279 PolarHBondContact O-N 3.35Å; V277-L280 WeakPolarHBondContact O-CB 3.49Å; V277-L280 PolarHBondContact O-N 2.91Å; V277-I281 HydrophobicContact CG1-CD1 3.92Å; V277-I281 HydrophobicContact CG1-CG1 4.41Å; V277-I281 VanDerWaalsContact O-CG1 3.23Å; V277-I281 WeakPolarHBondContact O-CG1 3.14Å; V277-I281 PolarHBondContact O-N 2.96Å; V277-Y416 HydrophobicContact CG2-CE1 4.39Å; V277-Y416 WeakPolarHBondContact CG2-OH 3.4Å; V277-L420 HydrophobicContact CG1-CD2 4.46Å; V277-W495 HydrophobicContact CG2-CE3 3.93Å; V277-W495 HydrophobicContact CG2-CZ3 4.1Å
278	I	95.9	Very high	94.8	Very high	77 Å²	77	48.3 Å²	48.3	40%	0.395	25%	0.252	S	S	.	.	H	α-helix	trans	-58.9	-46.8	175.2	-64.3	169.1	0	0	0	110.6	M272 L274 K275 L280 I281 C282	M272-I278 VanDerWaalsContact O-CG1 3.24Å; M272-I278 WeakPolarHBondContact O-CG1 3.44Å; L274-I278 WeakPolarHBondContact O-CG1 3.38Å; L274-I278 PolarHBondContact O-N 2.92Å; K275-I278 PolarHBondContact O-N 3.42Å; I278-L280 VanDerWaalsContact C-N 3.31Å; I278-L280 PolarHBondContact O-N 2.9Å; I278-I281 WeakPolarHBondContact O-CB 3.14Å; I278-I281 PolarHBondContact O-N 3.42Å; I278-C282 PolarHBondContact O-N 3.28Å; I278-C282 PolarHBondContact O-SG 3.17Å; I278-C282 VanDerWaalsContact O-SG 3.35Å
279	A	96.7	Very high	95.1	Very high	29 Å²	29	49.9 Å²	49.9	24%	0.24	26%	0.26	C	S	.	.	H	α-helix	trans	-61.2	-41	177.2	0	0	0	0	0	111.8	K275 P276 V277 C282 V283 V483 L487	K275-A279 WeakPolarHBondContact O-CB 3.3Å; K275-A279 PolarHBondContact O-N 3.24Å; P276-A279 PolarHBondContact O-N 3.5Å; V277-A279 VanDerWaalsContact C-N 3.34Å; V277-A279 PolarHBondContact O-N 3.35Å; A279-C282 PolarHBondContact O-N 3.08Å; A279-V283 VanDerWaalsContact O-CG2 3.27Å; A279-V283 WeakPolarHBondContact O-CG2 3.38Å; A279-V283 PolarHBondContact O-N 2.85Å; A279-V483 HydrophobicContact CB-CG1 4.32Å; A279-L487 HydrophobicContact CB-CD1 4.4Å; A279-L487 HydrophobicContact CB-CD2 4Å
280	L	96.7	Very high	95.3	Very high	0 Å²	0	45 Å²	45	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-63.5	-40.5	175	-169.8	66.7	0	0	0	112	P276 V277 I278 V283 Y284 F403 L420 L487 W495	P276-L280 WeakPolarHBondContact O-CB 3.14Å; P276-L280 PolarHBondContact O-N 3.35Å; V277-L280 WeakPolarHBondContact O-CB 3.49Å; V277-L280 PolarHBondContact O-N 2.91Å; I278-L280 VanDerWaalsContact C-N 3.31Å; I278-L280 PolarHBondContact O-N 2.9Å; L280-V283 WeakPolarHBondContact O-CB 3.45Å; L280-V283 PolarHBondContact O-N 3.47Å; L280-Y284 HydrophobicContact CD1-CD2 4.47Å; L280-Y284 HydrophobicContact CD1-CE1 3.98Å; L280-Y284 HydrophobicContact CD1-CE2 3.77Å; L280-Y284 VanDerWaalsContact CD1-CZ 3.48Å; L280-Y284 WeakPolarHBondContact CD1-OH 3.25Å; L280-Y284 HydrophobicContact CD2-CE2 3.69Å; L280-Y284 HydrophobicContact CG-CD2 3.96Å; L280-Y284 HydrophobicContact CG-CE1 4.49Å; L280-Y284 HydrophobicContact CG-CE2 3.43Å; L280-Y284 VanDerWaalsContact CG-CE2 3.43Å; L280-Y284 PolarHBondContact O-N 3.05Å; L280-F403 HydrophobicContact CD1-CD1 4.26Å; L280-F403 HydrophobicContact CD1-CE1 3.83Å; L280-F403 HydrophobicContact CD2-CD1 4.29Å; L280-F403 HydrophobicContact CD2-CE1 3.92Å; L280-L420 HydrophobicContact CD2-CD1 4.46Å; L280-L420 HydrophobicContact CD2-CD2 3.98Å; L280-L487 HydrophobicContact CB-CD1 4.07Å; L280-L487 HydrophobicContact CD1-CD1 3.84Å; L280-W495 HydrophobicContact CB-CH2 4.2Å; L280-W495 HydrophobicContact CB-CZ3 4.32Å; L280-W495 HydrophobicContact CD2-CH2 4.03Å; L280-W495 HydrophobicContact CD2-CZ3 3.84Å
281	I	94.8	Very high	95.5	Very high	28 Å²	28	38.7 Å²	38.7	14%	0.144	21%	0.211	C	C	.	.	H	α-helix	trans	-59.5	-49.8	174.7	-71.5	168.7	0	0	0	110.6	V277 I278 V283 Y284 L285 L423	V277-I281 HydrophobicContact CG1-CD1 3.92Å; V277-I281 HydrophobicContact CG1-CG1 4.41Å; V277-I281 VanDerWaalsContact O-CG1 3.23Å; V277-I281 WeakPolarHBondContact O-CG1 3.14Å; V277-I281 PolarHBondContact O-N 2.96Å; I278-I281 WeakPolarHBondContact O-CB 3.14Å; I278-I281 PolarHBondContact O-N 3.42Å; I281-V283 VanDerWaalsContact C-N 3.27Å; I281-V283 PolarHBondContact O-N 3.3Å; I281-Y284 PolarHBondContact O-N 2.93Å; I281-L285 HydrophobicContact CG2-CD1 3.62Å; I281-L285 HydrophobicContact CG2-CG 4.06Å; I281-L285 WeakPolarHBondContact O-CB 3.39Å; I281-L285 VanDerWaalsContact O-CG 3.32Å; I281-L285 WeakPolarHBondContact O-CG 3.37Å; I281-L285 PolarHBondContact O-N 2.87Å; I281-L423 HydrophobicContact CD1-CD1 3.63Å; I281-L423 HydrophobicContact CD1-CD2 4.23Å; I281-L423 HydrophobicContact CG1-CB 4.49Å; I281-L423 HydrophobicContact CG1-CD1 3.65Å; I281-L423 HydrophobicContact CG1-CD2 4.18Å; I281-L423 HydrophobicContact CG1-CG 4.31Å; I281-L423 HydrophobicContact CG2-CD2 4.27Å
282	C	96.4	Very high	95.7	Very high	74 Å²	74	39 Å²	39	50%	0.5	21%	0.214	S	C	.	.	H	α-helix	trans	-59.2	-40.4	178	-65.9	0	0	0	0	112	I278 A279 T286	I278-C282 PolarHBondContact O-N 3.28Å; I278-C282 PolarHBondContact O-SG 3.17Å; I278-C282 VanDerWaalsContact O-SG 3.35Å; A279-C282 PolarHBondContact O-N 3.08Å; C282-T286 WeakPolarHBondContact O-CG2 3.29Å; C282-T286 PolarHBondContact O-N 2.9Å; C282-T286 PolarHBondContact O-OG1 3.35Å
283	V	96.9	Very high	95.9	Very high	5 Å²	5	36.1 Å²	36.1	3%	0.03	20%	0.2	C	C	.	.	H	α-helix	trans	-60.8	-51	175	167.5	0	0	0	0	110.1	A279 L280 I281 T286 A287 W476 A480 V483 M484 L487	A279-V283 VanDerWaalsContact O-CG2 3.27Å; A279-V283 WeakPolarHBondContact O-CG2 3.38Å; A279-V283 PolarHBondContact O-N 2.85Å; L280-V283 WeakPolarHBondContact O-CB 3.45Å; L280-V283 PolarHBondContact O-N 3.47Å; I281-V283 VanDerWaalsContact C-N 3.27Å; I281-V283 PolarHBondContact O-N 3.3Å; V283-T286 PolarHBondContact O-N 3.49Å; V283-T286 PolarHBondContact O-OG1 3.06Å; V283-A287 WeakPolarHBondContact O-CB 3.35Å; V283-A287 PolarHBondContact O-N 2.96Å; V283-W476 HydrophobicContact CG1-CH2 4.2Å; V283-W476 HydrophobicContact CG1-CZ2 3.64Å; V283-A480 HydrophobicContact CG2-CB 4.44Å; V283-V483 HydrophobicContact CG2-CB 4.2Å; V283-V483 HydrophobicContact CG2-CG1 3.98Å; V283-M484 HydrophobicContact CG1-CB 4.32Å; V283-M484 HydrophobicContact CG1-SD 3.53Å; V283-M484 VanDerWaalsContact CG1-SD 3.53Å; V283-L487 HydrophobicContact CG2-CD1 4.49Å
284	Y	95	Very high	96	Very high	6 Å²	6	31.9 Å²	31.9	2%	0.024	17%	0.172	C	C	.	.	H	α-helix	trans	-68.9	-38.5	-177.9	-68.6	-23.8	0	0	0	114.5	L280 I281 T286 Q400 H404 A424 G427	L280-Y284 HydrophobicContact CD1-CD2 4.47Å; L280-Y284 HydrophobicContact CD1-CE1 3.98Å; L280-Y284 HydrophobicContact CD1-CE2 3.77Å; L280-Y284 VanDerWaalsContact CD1-CZ 3.48Å; L280-Y284 WeakPolarHBondContact CD1-OH 3.25Å; L280-Y284 HydrophobicContact CD2-CE2 3.69Å; L280-Y284 HydrophobicContact CG-CD2 3.96Å; L280-Y284 HydrophobicContact CG-CE1 4.49Å; L280-Y284 HydrophobicContact CG-CE2 3.43Å; L280-Y284 VanDerWaalsContact CG-CE2 3.43Å; L280-Y284 PolarHBondContact O-N 3.05Å; I281-Y284 PolarHBondContact O-N 2.93Å; Y284-T286 PolarHBondContact O-N 2.94Å; Y284-Q400 HydrophobicContact CE1-CG 3.77Å; Y284-Q400 HydrophobicContact CE2-CG 4.32Å; Y284-Q400 WeakPolarHBondContact OH-CG 3.34Å; Y284-H404 AromaticContact CE2-NE2 3.12Å; Y284-H404 WeakPolarHBondContact CE2-NE2 3.48Å; Y284-H404 AromaticContact CZ-NE2 3.37Å; Y284-H404 PolarHBondContact OH-CD2 3.19Å; Y284-H404 PolarHBondContact OH-NE2 3.47Å; Y284-A424 HydrophobicContact CD2-CB 3.94Å; Y284-A424 HydrophobicContact CE2-CB 4.32Å; Y284-A424 HydrophobicContact CG-CB 4.26Å; Y284-G427 WeakPolarHBondContact O-CA 3.3Å
285	L	95.5	Very high	96	Very high	50 Å²	50	33.5 Å²	33.5	26%	0.262	18%	0.181	S	C	.	.	H	α-helix	trans	-63.6	-23	177.6	-71.2	178	0	0	0	112.6	I281 L426 W430	I281-L285 HydrophobicContact CG2-CD1 3.62Å; I281-L285 HydrophobicContact CG2-CG 4.06Å; I281-L285 WeakPolarHBondContact O-CB 3.39Å; I281-L285 VanDerWaalsContact O-CG 3.32Å; I281-L285 WeakPolarHBondContact O-CG 3.37Å; I281-L285 PolarHBondContact O-N 2.87Å; L285-L426 HydrophobicContact CD2-CD2 4.04Å; L285-L426 HydrophobicContact CD2-CG 4.05Å; L285-W430 VanDerWaalsContact O-CZ2 3.27Å; L285-W430 WeakPolarHBondContact O-CZ2 3.47Å; L285-W430 PolarHBondContact O-NE1 3.48Å
286	T	96.7	Very high	95.9	Very high	52 Å²	52	25.7 Å²	25.7	32%	0.319	15%	0.152	S	C	.	.	H	α-helix	trans	-106.9	-20	-176.9	55.1	0	0	0	0	114.1	C282 V283 Y284 K288 I289 W476	C282-T286 WeakPolarHBondContact O-CG2 3.29Å; C282-T286 PolarHBondContact O-N 2.9Å; C282-T286 PolarHBondContact O-OG1 3.35Å; V283-T286 PolarHBondContact O-N 3.49Å; V283-T286 PolarHBondContact O-OG1 3.06Å; Y284-T286 PolarHBondContact O-N 2.94Å; T286-K288 PolarHBondContact O-N 3.27Å; T286-I289 HydrophobicContact CG2-CD1 4.38Å; T286-I289 WeakPolarHBondContact O-CG1 3.5Å; T286-I289 PolarHBondContact O-N 3.26Å; T286-W476 PolarHBondContact OG1-NE1 3.27Å
287	A	96	Very high	95.9	Very high	1 Å²	1	25.1 Å²	25.1	1%	0.008	15%	0.148	C	C	.	.	H	α-helix	trans	-63.4	-35.2	-169.1	0	0	0	0	0	115.1	V283 Y343 Y347 W476	V283-A287 WeakPolarHBondContact O-CB 3.35Å; V283-A287 PolarHBondContact O-N 2.96Å; A287-Y343 WeakPolarHBondContact CB-OH 3.11Å; A287-Y347 WeakPolarHBondContact O-CE2 3.5Å; A287-Y347 PolarHBondContact O-OH 3.47Å; A287-W476 VanDerWaalsContact CA-CE2 3.44Å; A287-W476 HydrophobicContact CB-CD2 4.48Å; A287-W476 HydrophobicContact CB-CH2 3.84Å; A287-W476 HydrophobicContact CB-CZ2 3.27Å
288	K	96.3	Very high	95.9	Very high	44 Å²	44	25.2 Å²	25.2	19%	0.191	15%	0.148	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.2	2.8	-173.4	-65.4	177.5	175.9	176.1	0	113.7	T286 A290 F291 A292 G428	T286-K288 PolarHBondContact O-N 3.27Å; K288-A290 PolarHBondContact O-N 2.96Å; K288-F291 HydrophobicContact CB-CD2 4.43Å; K288-F291 HydrophobicContact CG-CD2 4.34Å; K288-F291 PolarHBondContact O-N 2.89Å; K288-A292 PolarHBondContact O-N 2.94Å; K288-G428 VanDerWaalsContact CD-CA 3.42Å
289	I	97	Very high	95.7	Very high	47 Å²	47	23.3 Å²	23.3	24%	0.241	15%	0.147	C	C	.	.	G	3₁₀ helix	trans	-54.8	-40.4	171.7	-61.1	172.2	0	0	0	110.2	T286 F291 A292 W430 P431 I472	T286-I289 HydrophobicContact CG2-CD1 4.38Å; T286-I289 WeakPolarHBondContact O-CG1 3.5Å; T286-I289 PolarHBondContact O-N 3.26Å; I289-F291 PolarHBondContact O-N 3.35Å; I289-F291 VanDerWaalsContact O-N 3.16Å; I289-A292 WeakPolarHBondContact O-CB 3.23Å; I289-A292 PolarHBondContact O-N 3.48Å; I289-W430 HydrophobicContact CD1-CH2 3.78Å; I289-W430 HydrophobicContact CD1-CZ2 3.71Å; I289-W430 HydrophobicContact CG1-CH2 3.94Å; I289-W430 HydrophobicContact CG1-CZ2 3.75Å; I289-P431 HydrophobicContact CG1-CB 4.18Å; I289-P431 HydrophobicContact CG1-CG 4.02Å; I289-I472 HydrophobicContact CB-CG2 4.32Å; I289-I472 HydrophobicContact CG2-CD1 4.15Å; I289-I472 HydrophobicContact CG2-CG2 4.02Å
290	A	96.9	Very high	95.5	Very high	3 Å²	3	25.8 Å²	25.8	3%	0.025	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-59.4	-26.7	179.4	0	0	0	0	0	114.3	K288 G469 G473	K288-A290 PolarHBondContact O-N 2.96Å; A290-G469 VanDerWaalsContact CA-O 3.29Å; A290-G469 WeakPolarHBondContact CA-O 3.17Å; A290-G469 VanDerWaalsContact CB-O 3.26Å; A290-G469 WeakPolarHBondContact CB-O 3.5Å; A290-G473 VanDerWaalsContact CB-CA 3.5Å
291	F	96.8	Very high	95.4	Very high	4 Å²	4	26.9 Å²	26.9	2%	0.018	16%	0.161	C	C	.	.	G	3₁₀ helix	trans	-106.1	-2	-174.4	-43.9	-42.4	0	0	0	112.6	K288 I289 A293 A294 D295 Y347 R350 N351 I396	K288-F291 HydrophobicContact CB-CD2 4.43Å; K288-F291 HydrophobicContact CG-CD2 4.34Å; K288-F291 PolarHBondContact O-N 2.89Å; I289-F291 PolarHBondContact O-N 3.35Å; I289-F291 VanDerWaalsContact O-N 3.16Å; F291-A293 PolarHBondContact O-N 2.99Å; F291-A294 PolarHBondContact O-N 3.19Å; F291-A294 VanDerWaalsContact O-N 3.09Å; F291-D295 WeakPolarHBondContact O-CB 3.06Å; F291-D295 PolarHBondContact O-N 2.67Å; F291-Y347 HydrophobicContact CE2-CD2 4.08Å; F291-Y347 AromaticContact CE2-CE2 3.63Å; F291-Y347 HydrophobicContact CE2-CE2 3.63Å; F291-Y347 HydrophobicContact CZ-CD1 4.44Å; F291-Y347 AromaticContact CZ-CD2 3.72Å; F291-Y347 HydrophobicContact CZ-CD2 3.72Å; F291-Y347 HydrophobicContact CZ-CE1 4.14Å; F291-Y347 AromaticContact CZ-CE2 3.39Å; F291-Y347 HydrophobicContact CZ-CE2 3.39Å; F291-Y347 HydrophobicContact CZ-CG 4.25Å; F291-Y347 AromaticContact CZ-CZ 3.63Å; F291-R350 HydrophobicContact CD1-CG 3.74Å; F291-R350 HydrophobicContact CD2-CG 3.97Å; F291-R350 HydrophobicContact CE1-CB 3.97Å; F291-R350 HydrophobicContact CE1-CG 3.48Å; F291-R350 VanDerWaalsContact CE1-CG 3.48Å; F291-R350 HydrophobicContact CE2-CB 4.49Å; F291-R350 HydrophobicContact CE2-CG 3.71Å; F291-R350 HydrophobicContact CG-CG 3.99Å; F291-R350 HydrophobicContact CZ-CB 3.87Å; F291-R350 HydrophobicContact CZ-CG 3.45Å; F291-R350 VanDerWaalsContact CZ-CG 3.45Å; F291-N351 HydrophobicContact CE1-CB 4.02Å; F291-I396 HydrophobicContact CE2-CD1 4.32Å
292	A	96.3	Very high	95.4	Very high	7 Å²	7	25.7 Å²	25.7	6%	0.058	16%	0.155	C	C	.	.	H	α-helix	trans	-56.1	-46	-170.3	0	0	0	0	0	113.6	K288 I289 G296 P431 A435	K288-A292 PolarHBondContact O-N 2.94Å; I289-A292 WeakPolarHBondContact O-CB 3.23Å; I289-A292 PolarHBondContact O-N 3.48Å; A292-G296 WeakPolarHBondContact O-CA 3.07Å; A292-G296 PolarHBondContact O-N 3.38Å; A292-P431 HydrophobicContact CB-CB 3.72Å; A292-A435 HydrophobicContact CB-CB 3.91Å
293	A	95.9	Very high	95.1	Very high	6 Å²	6	25 Å²	25	5%	0.05	15%	0.145	C	C	.	.	H	α-helix	trans	-70	-39.9	177.7	0	0	0	0	0	112.1	F291 D295 I297 T298 L465 I466	F291-A293 PolarHBondContact O-N 2.99Å; A293-D295 PolarHBondContact O-N 3.5Å; A293-I297 HydrophobicContact CB-CD1 4.1Å; A293-I297 WeakPolarHBondContact O-CA 3.39Å; A293-I297 VanDerWaalsContact O-CB 3.3Å; A293-I297 WeakPolarHBondContact O-CB 3.36Å; A293-I297 PolarHBondContact O-N 3.49Å; A293-T298 PolarHBondContact O-N 3.49Å; A293-L465 HydrophobicContact CB-CB 3.77Å; A293-I466 HydrophobicContact CB-CD1 3.77Å; A293-I466 HydrophobicContact CB-CG1 4.06Å
294	A	96.4	Very high	94.8	Very high	5 Å²	5	30.3 Å²	30.3	4%	0.041	17%	0.17	C	C	.	.	H	α-helix	trans	-63.3	-42.6	178.2	0	0	0	0	0	111.5	F291 T298 F357 I466	F291-A294 PolarHBondContact O-N 3.19Å; F291-A294 VanDerWaalsContact O-N 3.09Å; A294-T298 WeakPolarHBondContact CA-OG1 3.34Å; A294-T298 VanDerWaalsContact O-CB 3.25Å; A294-T298 WeakPolarHBondContact O-CB 3.24Å; A294-T298 PolarHBondContact O-OG1 3.06Å; A294-F357 HydrophobicContact CB-CD2 4.38Å; A294-I466 HydrophobicContact CB-CD1 3.94Å
295	D	94.3	Very high	94.6	Very high	70 Å²	70	32.2 Å²	32.2	37%	0.374	18%	0.18	S	C	.	.	H	α-helix	trans	-81.5	-36.8	-176.7	-66.3	-10.5	0	0	0	112.3	F291 A293 R350 Q389 V432	F291-D295 WeakPolarHBondContact O-CB 3.06Å; F291-D295 PolarHBondContact O-N 2.67Å; A293-D295 PolarHBondContact O-N 3.5Å; D295-R350 IonicContact OD1-CZ 2.7Å; D295-R350 IonicContact OD1-NH2 2.71Å; D295-R350 PolarHBondContact OD1-NH2 3.35Å; D295-R350 IonicContact OD2-NH2 2.67Å; D295-R350 PolarHBondContact OD2-NH2 2.89Å; D295-Q389 PolarHBondContact OD1-NE2 3.49Å; D295-V432 HydrophobicContact CB-CG2 4.43Å
296	G	92.9	Very high	94.4	Very high	16 Å²	16	34 Å²	34	17%	0.165	19%	0.194	C	C	.	.	H	α-helix	trans	-92.3	-30	-173.9	0	0	0	0	0	116	A292	A292-G296 WeakPolarHBondContact O-CA 3.07Å; A292-G296 PolarHBondContact O-N 3.38Å
297	I	95.2	Very high	94	Very high	4 Å²	4	31.8 Å²	31.8	2%	0.021	18%	0.179	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.8	-33.6	-164.6	-51.7	176.2	0	0	0	112.3	A293 G299 L300 K301 A435 L436 V439 Y462 L465	A293-I297 HydrophobicContact CB-CD1 4.1Å; A293-I297 WeakPolarHBondContact O-CA 3.39Å; A293-I297 VanDerWaalsContact O-CB 3.3Å; A293-I297 WeakPolarHBondContact O-CB 3.36Å; A293-I297 PolarHBondContact O-N 3.49Å; I297-G299 VanDerWaalsContact C-N 3.32Å; I297-G299 PolarHBondContact O-N 2.79Å; I297-L300 WeakPolarHBondContact O-CA 3.26Å; I297-L300 WeakPolarHBondContact O-CB 3.17Å; I297-L300 PolarHBondContact O-N 2.93Å; I297-K301 HydrophobicContact CG2-CG 3.87Å; I297-K301 PolarHBondContact O-N 3.32Å; I297-A435 HydrophobicContact CD1-CB 4.11Å; I297-L436 HydrophobicContact CG1-CD2 3.98Å; I297-L436 HydrophobicContact CG1-CG 4.44Å; I297-V439 HydrophobicContact CD1-CB 4.08Å; I297-V439 HydrophobicContact CD1-CG2 4.03Å; I297-V439 HydrophobicContact CG2-CG2 4.48Å; I297-Y462 HydrophobicContact CB-CD2 3.84Å; I297-Y462 HydrophobicContact CB-CE2 4.19Å; I297-Y462 HydrophobicContact CG2-CD2 3.55Å; I297-Y462 HydrophobicContact CG2-CE2 4.26Å; I297-Y462 HydrophobicContact CG2-CG 4.29Å; I297-L465 HydrophobicContact CD1-CD1 3.84Å
298	T	95.7	Very high	93.5	Very high	2 Å²	2	34.1 Å²	34.1	1%	0.012	20%	0.195	C	C	.	.	H	α-helix	trans	-51.8	-46.7	-176.6	-52.9	0	0	0	0	113.3	A293 A294 L300 K301 L302 F357 I361 Y462	A293-T298 PolarHBondContact O-N 3.49Å; A294-T298 WeakPolarHBondContact CA-OG1 3.34Å; A294-T298 VanDerWaalsContact O-CB 3.25Å; A294-T298 WeakPolarHBondContact O-CB 3.24Å; A294-T298 PolarHBondContact O-OG1 3.06Å; T298-L300 VanDerWaalsContact C-N 3.3Å; T298-L300 PolarHBondContact O-N 3.17Å; T298-K301 PolarHBondContact O-N 2.99Å; T298-L302 WeakPolarHBondContact O-CG 3.39Å; T298-L302 PolarHBondContact O-N 2.67Å; T298-F357 HydrophobicContact CG2-CB 4.08Å; T298-F357 HydrophobicContact CG2-CD1 3.62Å; T298-F357 HydrophobicContact CG2-CE1 4.31Å; T298-F357 HydrophobicContact CG2-CG 3.98Å; T298-I361 HydrophobicContact CG2-CD1 4.09Å; T298-I361 HydrophobicContact CG2-CG1 4.27Å; T298-Y462 PolarHBondContact OG1-OH 2.69Å
299	G	92.4	Very high	92.8	Very high	36 Å²	36	37.7 Å²	37.7	37%	0.371	21%	0.21	S	C	.	.	H	α-helix	trans	-62.2	-38	178.5	0	0	0	0	0	112.7	I297 I303	I297-G299 VanDerWaalsContact C-N 3.32Å; I297-G299 PolarHBondContact O-N 2.79Å; G299-I303 WeakPolarHBondContact O-CD1 3.33Å; G299-I303 VanDerWaalsContact O-CG1 3.3Å; G299-I303 WeakPolarHBondContact O-CG1 3.41Å; G299-I303 PolarHBondContact O-N 3.07Å
300	L	92.2	Very high	91.8	Very high	82 Å²	82	39.9 Å²	39.9	43%	0.429	22%	0.222	S	C	.	.	H	α-helix	trans	-67.8	-39.8	175.8	-58.4	178.9	0	0	0	111.1	I297 T298 L302 I303 E304 L436	I297-L300 WeakPolarHBondContact O-CA 3.26Å; I297-L300 WeakPolarHBondContact O-CB 3.17Å; I297-L300 PolarHBondContact O-N 2.93Å; T298-L300 VanDerWaalsContact C-N 3.3Å; T298-L300 PolarHBondContact O-N 3.17Å; L300-L302 PolarHBondContact O-N 3.1Å; L300-I303 WeakPolarHBondContact O-CB 3.36Å; L300-I303 PolarHBondContact O-N 2.88Å; L300-I303 VanDerWaalsContact O-N 3.15Å; L300-E304 WeakPolarHBondContact O-CG 3.21Å; L300-E304 PolarHBondContact O-N 3.05Å; L300-L436 HydrophobicContact CD1-CD2 3.64Å
301	K	94	Very high	91.1	Very high	22 Å²	22	42.9 Å²	42.9	10%	0.096	24%	0.236	C	C	.	.	H	α-helix	trans	-64.2	-38.9	177.3	-73.9	-75.2	161.9	-165.9	0	112.9	I297 T298 I303 E304 L305 I361 E460 Y462	I297-K301 HydrophobicContact CG2-CG 3.87Å; I297-K301 PolarHBondContact O-N 3.32Å; T298-K301 PolarHBondContact O-N 2.99Å; K301-I303 VanDerWaalsContact C-N 3.3Å; K301-I303 PolarHBondContact O-N 2.91Å; K301-E304 WeakPolarHBondContact CD-OE2 3.5Å; K301-E304 VanDerWaalsContact CE-OE2 3.29Å; K301-E304 WeakPolarHBondContact CE-OE2 3.21Å; K301-E304 IonicContact NZ-OE2 2.93Å; K301-E304 PolarHBondContact NZ-OE2 2.95Å; K301-E304 PolarHBondContact O-N 3.35Å; K301-L305 VanDerWaalsContact O-CG 3.3Å; K301-L305 WeakPolarHBondContact O-CG 3.2Å; K301-L305 PolarHBondContact O-N 3.33Å; K301-I361 HydrophobicContact CB-CD1 3.96Å; K301-I361 HydrophobicContact CB-CG1 4.42Å; K301-I361 HydrophobicContact CB-CG2 4.13Å; K301-E460 WeakPolarHBondContact CD-OE2 3.44Å; K301-E460 VanDerWaalsContact CE-OE2 3.25Å; K301-E460 WeakPolarHBondContact CE-OE2 3.49Å; K301-E460 IonicContact NZ-OE2 2.71Å; K301-E460 PolarHBondContact NZ-OE2 3.11Å; K301-Y462 HydrophobicContact CD-CG 4.43Å; K301-Y462 HydrophobicContact CG-CD1 4.29Å; K301-Y462 HydrophobicContact CG-CD2 4.22Å; K301-Y462 HydrophobicContact CG-CG 4.03Å
302	L	93.9	Very high	90.4	Very high	3 Å²	3	44.1 Å²	44.1	2%	0.016	24%	0.242	C	C	.	.	H	α-helix	trans	-60.7	-42.3	172.7	-68.5	169.1	0	0	0	111.4	T298 L300 L305 V307 L312 I361 Y378 I382 F386	T298-L302 WeakPolarHBondContact O-CG 3.39Å; T298-L302 PolarHBondContact O-N 2.67Å; L300-L302 PolarHBondContact O-N 3.1Å; L302-L305 PolarHBondContact O-N 3.21Å; L302-V307 HydrophobicContact CB-CB 4.3Å; L302-V307 HydrophobicContact CB-CG2 4.27Å; L302-V307 HydrophobicContact CD2-CG2 4.32Å; L302-V307 WeakPolarHBondContact O-CB 3.34Å; L302-V307 VanDerWaalsContact O-CG2 3.24Å; L302-V307 WeakPolarHBondContact O-CG2 3.33Å; L302-V307 PolarHBondContact O-N 2.86Å; L302-L312 HydrophobicContact CB-CD1 3.83Å; L302-L312 HydrophobicContact CB-CD2 4.35Å; L302-L312 HydrophobicContact CD1-CD2 3.83Å; L302-I361 HydrophobicContact CD2-CD1 3.44Å; L302-I361 VanDerWaalsContact CD2-CD1 3.44Å; L302-I361 HydrophobicContact CG-CD1 3.54Å; L302-Y378 VanDerWaalsContact CD2-OH 3.25Å; L302-Y378 WeakPolarHBondContact CD2-OH 3.39Å; L302-I382 HydrophobicContact CD2-CD1 4.44Å; L302-F386 HydrophobicContact CD1-CE2 4.09Å; L302-F386 HydrophobicContact CD1-CZ 4.3Å
303	I	90.4	Very high	89.5	Confident	59 Å²	59	46.9 Å²	46.9	30%	0.303	27%	0.266	S	S	.	.	H	α-helix	trans	-65.9	-42.6	177.6	-66	168	0	0	0	111.2	G299 L300 K301 L305 V306 K309 L312	G299-I303 WeakPolarHBondContact O-CD1 3.33Å; G299-I303 VanDerWaalsContact O-CG1 3.3Å; G299-I303 WeakPolarHBondContact O-CG1 3.41Å; G299-I303 PolarHBondContact O-N 3.07Å; L300-I303 WeakPolarHBondContact O-CB 3.36Å; L300-I303 PolarHBondContact O-N 2.88Å; L300-I303 VanDerWaalsContact O-N 3.15Å; K301-I303 VanDerWaalsContact C-N 3.3Å; K301-I303 PolarHBondContact O-N 2.91Å; I303-L305 PolarHBondContact O-N 3.06Å; I303-V306 WeakPolarHBondContact O-CA 3.28Å; I303-V306 PolarHBondContact O-N 3.49Å; I303-K309 HydrophobicContact CD1-CD 4.36Å; I303-K309 HydrophobicContact CD1-CG 3.93Å; I303-K309 HydrophobicContact CG1-CG 3.93Å; I303-K309 HydrophobicContact CG2-CD 4.45Å; I303-K309 VanDerWaalsContact CG2-CE 3.41Å; I303-K309 HydrophobicContact CG2-CG 4.19Å; I303-L312 HydrophobicContact CG1-CD1 3.85Å
304	E	90.4	Very high	88.8	Confident	118 Å²	118	51.4 Å²	51.4	55%	0.551	28%	0.284	S	S	*	.	H	α-helix	trans	-60.2	-35.3	175.1	-74.7	172.5	-161.8	0	0	112	L300 K301 V306	L300-E304 WeakPolarHBondContact O-CG 3.21Å; L300-E304 PolarHBondContact O-N 3.05Å; K301-E304 WeakPolarHBondContact CD-OE2 3.5Å; K301-E304 VanDerWaalsContact CE-OE2 3.29Å; K301-E304 WeakPolarHBondContact CE-OE2 3.21Å; K301-E304 IonicContact NZ-OE2 2.93Å; K301-E304 PolarHBondContact NZ-OE2 2.95Å; K301-E304 PolarHBondContact O-N 3.35Å; E304-V306 PolarHBondContact O-N 2.89Å; E304-V306 VanDerWaalsContact O-N 3.14Å
305	L	92.3	Very high	88.3	Confident	45 Å²	45	52 Å²	52	24%	0.236	29%	0.287	C	S	.	.	T	Hydrogen-bonded Turn	trans	-76.5	11.8	173.8	-66.1	178.8	0	0	0	114	K301 L302 I303 V307 I361 T364 P365	K301-L305 VanDerWaalsContact O-CG 3.3Å; K301-L305 WeakPolarHBondContact O-CG 3.2Å; K301-L305 PolarHBondContact O-N 3.33Å; L302-L305 PolarHBondContact O-N 3.21Å; I303-L305 PolarHBondContact O-N 3.06Å; L305-V307 VanDerWaalsContact C-N 3.28Å; L305-V307 PolarHBondContact O-N 3.22Å; L305-I361 HydrophobicContact CD1-CG2 3.96Å; L305-I361 WeakPolarHBondContact CD1-O 3.44Å; L305-T364 HydrophobicContact CB-CG2 4.08Å; L305-T364 HydrophobicContact CD1-CG2 3.77Å; L305-P365 HydrophobicContact CD1-CG 4.37Å; L305-P365 HydrophobicContact CD2-CG 4.06Å
306	V	90.1	Very high	87.6	Confident	89 Å²	89	51.3 Å²	51.3	54%	0.539	29%	0.291	S	S	.	.	T	Hydrogen-bonded Turn	trans	67.6	26.1	177.2	-159.3	0	0	0	0	112.5	I303 E304	I303-V306 WeakPolarHBondContact O-CA 3.28Å; I303-V306 PolarHBondContact O-N 3.49Å; E304-V306 PolarHBondContact O-N 2.89Å; E304-V306 VanDerWaalsContact O-N 3.14Å
307	V	89.7	Confident	87.3	Confident	4 Å²	4	53.5 Å²	53.5	2%	0.024	30%	0.3	C	S	.	.			trans	-72.7	127.1	166.4	-173.6	0	0	0	0	108.3	L302 L305 K309 L312 T364 F374 Y378 Y379	L302-V307 HydrophobicContact CB-CB 4.3Å; L302-V307 HydrophobicContact CB-CG2 4.27Å; L302-V307 HydrophobicContact CD2-CG2 4.32Å; L302-V307 WeakPolarHBondContact O-CB 3.34Å; L302-V307 VanDerWaalsContact O-CG2 3.24Å; L302-V307 WeakPolarHBondContact O-CG2 3.33Å; L302-V307 PolarHBondContact O-N 2.86Å; L305-V307 VanDerWaalsContact C-N 3.28Å; L305-V307 PolarHBondContact O-N 3.22Å; V307-K309 PolarHBondContact O-N 3.44Å; V307-L312 HydrophobicContact CB-CD1 4.3Å; V307-L312 HydrophobicContact CG1-CD1 4.12Å; V307-L312 HydrophobicContact CG1-CD2 3.82Å; V307-L312 HydrophobicContact CG1-CG 3.78Å; V307-T364 HydrophobicContact CG2-CG2 4.04Å; V307-F374 HydrophobicContact CB-CE2 4.27Å; V307-F374 HydrophobicContact CG2-CD2 4.22Å; V307-F374 HydrophobicContact CG2-CE1 4.5Å; V307-F374 HydrophobicContact CG2-CE2 3.68Å; V307-F374 HydrophobicContact CG2-CZ 3.83Å; V307-Y378 HydrophobicContact CG1-CE1 4.3Å; V307-Y378 HydrophobicContact CG2-CE1 4.14Å; V307-Y379 HydrophobicContact CG1-CE1 3.98Å
308	P	85.3	Confident	86.9	Confident	50 Å²	50	56.2 Å²	56.2	33%	0.325	32%	0.319	S	S	.	.			trans	-58.8	134.2	-179.5	-22.4	32.4	0	0	0	112.4	D310 E311 L312 Y379	P308-D310 VanDerWaalsContact C-N 3.33Å; P308-D310 WeakPolarHBondContact CB-OD1 3.21Å; P308-D310 PolarHBondContact O-N 3.27Å; P308-E311 HydrophobicContact CB-CB 4.2Å; P308-E311 HydrophobicContact CB-CG 3.97Å; P308-E311 HydrophobicContact CG-CG 4.27Å; P308-E311 PolarHBondContact O-N 3.37Å; P308-L312 WeakPolarHBondContact O-CG 3.4Å; P308-L312 PolarHBondContact O-N 3.44Å; P308-L312 VanDerWaalsContact O-N 3.16Å; P308-Y379 WeakPolarHBondContact CD-OH 3.22Å
309	K	80.1	Confident	86.6	Confident	120 Å²	120	56.8 Å²	56.8	52%	0.522	32%	0.321	S	S	.	.	H	α-helix	trans	-66.1	-36.2	-177.1	-67.1	-179	-179.7	-178.6	0	112.5	I303 V307 A313	I303-K309 HydrophobicContact CD1-CD 4.36Å; I303-K309 HydrophobicContact CD1-CG 3.93Å; I303-K309 HydrophobicContact CG1-CG 3.93Å; I303-K309 HydrophobicContact CG2-CD 4.45Å; I303-K309 VanDerWaalsContact CG2-CE 3.41Å; I303-K309 HydrophobicContact CG2-CG 4.19Å; V307-K309 PolarHBondContact O-N 3.44Å; K309-A313 WeakPolarHBondContact O-CB 3.35Å; K309-A313 PolarHBondContact O-N 3.25Å
310	D	76.4	Confident	86.5	Confident	92 Å²	92	55.9 Å²	55.9	49%	0.492	31%	0.308	S	S	.	.	H	α-helix	trans	-63.9	-48.1	176.9	54.2	-51.4	0	0	0	111.1	P308 L312 A313 F314	P308-D310 VanDerWaalsContact C-N 3.33Å; P308-D310 WeakPolarHBondContact CB-OD1 3.21Å; P308-D310 PolarHBondContact O-N 3.27Å; D310-L312 VanDerWaalsContact C-N 3.34Å; D310-L312 PolarHBondContact O-N 3.4Å; D310-A313 WeakPolarHBondContact O-CB 3.45Å; D310-A313 PolarHBondContact O-N 3.49Å; D310-A313 VanDerWaalsContact O-N 3.12Å; D310-F314 WeakPolarHBondContact O-CD2 3.25Å; D310-F314 PolarHBondContact O-N 3.11Å
311	E	83	Confident	86.4	Confident	66 Å²	66	55.1 Å²	55.1	31%	0.308	31%	0.309	S	S	.	.	H	α-helix	trans	-61.9	-40.5	176.1	-65.2	-72.2	-172.4	0	0	111.8	P308 A313 F314 L315 Y379	P308-E311 HydrophobicContact CB-CB 4.2Å; P308-E311 HydrophobicContact CB-CG 3.97Å; P308-E311 HydrophobicContact CG-CG 4.27Å; P308-E311 PolarHBondContact O-N 3.37Å; E311-A313 PolarHBondContact O-N 3.02Å; E311-F314 PolarHBondContact O-N 3.37Å; E311-L315 PolarHBondContact O-N 2.99Å; E311-Y379 HydrophobicContact CB-CD1 4.34Å; E311-Y379 HydrophobicContact CB-CE1 3.6Å; E311-Y379 HydrophobicContact CG-CE1 4.33Å
312	L	82.2	Confident	86.3	Confident	30 Å²	30	56.4 Å²	56.4	16%	0.157	32%	0.316	C	S	.	.	H	α-helix	trans	-62.6	-40.5	173	-70.2	175	0	0	0	112.5	L302 I303 V307 P308 D310 F314 L315	L302-L312 HydrophobicContact CB-CD1 3.83Å; L302-L312 HydrophobicContact CB-CD2 4.35Å; L302-L312 HydrophobicContact CD1-CD2 3.83Å; I303-L312 HydrophobicContact CG1-CD1 3.85Å; V307-L312 HydrophobicContact CB-CD1 4.3Å; V307-L312 HydrophobicContact CG1-CD1 4.12Å; V307-L312 HydrophobicContact CG1-CD2 3.82Å; V307-L312 HydrophobicContact CG1-CG 3.78Å; P308-L312 WeakPolarHBondContact O-CG 3.4Å; P308-L312 PolarHBondContact O-N 3.44Å; P308-L312 VanDerWaalsContact O-N 3.16Å; D310-L312 VanDerWaalsContact C-N 3.34Å; D310-L312 PolarHBondContact O-N 3.4Å; L312-F314 VanDerWaalsContact C-N 3.31Å; L312-F314 PolarHBondContact O-N 3.41Å; L312-L315 HydrophobicContact CD2-CD1 4.12Å; L312-L315 WeakPolarHBondContact O-CB 3.49Å; L312-L315 PolarHBondContact O-N 3Å
313	A	76.9	Confident	86.2	Confident	66 Å²	66	57.6 Å²	57.6	55%	0.545	32%	0.321	S	S	.	.	H	α-helix	trans	-65.6	-35.9	176.9	0	0	0	0	0	111.7	K309 D310 E311 L315 A316	K309-A313 WeakPolarHBondContact O-CB 3.35Å; K309-A313 PolarHBondContact O-N 3.25Å; D310-A313 WeakPolarHBondContact O-CB 3.45Å; D310-A313 PolarHBondContact O-N 3.49Å; D310-A313 VanDerWaalsContact O-N 3.12Å; E311-A313 PolarHBondContact O-N 3.02Å; A313-L315 PolarHBondContact O-N 3.02Å; A313-A316 WeakPolarHBondContact O-CB 3.41Å; A313-A316 PolarHBondContact O-N 3.42Å; A313-A316 VanDerWaalsContact O-N 3.12Å
314	F	82	Confident	86.3	Confident	100 Å²	100	56.6 Å²	56.6	44%	0.439	32%	0.317	S	S	.	.	H	α-helix	trans	-64.1	-25.1	174.9	-77.8	-64.1	0	0	0	113.2	D310 E311 L312 A316 V317 P318	D310-F314 WeakPolarHBondContact O-CD2 3.25Å; D310-F314 PolarHBondContact O-N 3.11Å; E311-F314 PolarHBondContact O-N 3.37Å; L312-F314 VanDerWaalsContact C-N 3.31Å; L312-F314 PolarHBondContact O-N 3.41Å; F314-A316 PolarHBondContact O-N 3.2Å; F314-V317 PolarHBondContact O-N 2.85Å; F314-P318 WeakPolarHBondContact O-CD 3.31Å
315	L	85.3	Confident	86.4	Confident	19 Å²	19	55.3 Å²	55.3	10%	0.099	31%	0.313	C	S	.	.	T	Hydrogen-bonded Turn	trans	-63.1	-23.1	173.9	-57.9	-175.2	0	0	0	113	E311 L312 A313 V317 P318 I319 I382 L383	E311-L315 PolarHBondContact O-N 2.99Å; L312-L315 HydrophobicContact CD2-CD1 4.12Å; L312-L315 WeakPolarHBondContact O-CB 3.49Å; L312-L315 PolarHBondContact O-N 3Å; A313-L315 PolarHBondContact O-N 3.02Å; L315-V317 VanDerWaalsContact C-N 3.33Å; L315-P318 WeakPolarHBondContact O-CD 3.43Å; L315-P318 WeakPolarHBondContact O-CG 3.1Å; L315-I319 WeakPolarHBondContact O-CD1 3.36Å; L315-I319 WeakPolarHBondContact O-CG1 3.42Å; L315-I382 HydrophobicContact CD1-CB 4.33Å; L315-I382 HydrophobicContact CD1-CG2 3.67Å; L315-L383 HydrophobicContact CB-CD1 4.43Å; L315-L383 HydrophobicContact CD2-CB 4.22Å
316	A	79.9	Confident	86.5	Confident	55 Å²	55	54.4 Å²	54.4	46%	0.455	31%	0.308	S	S	.	.	H	α-helix	trans	-69.7	-29.9	177.5	0	0	0	0	0	112.7	A313 F314 I319 V320	A313-A316 WeakPolarHBondContact O-CB 3.41Å; A313-A316 PolarHBondContact O-N 3.42Å; A313-A316 VanDerWaalsContact O-N 3.12Å; F314-A316 PolarHBondContact O-N 3.2Å; A316-I319 WeakPolarHBondContact O-CB 3.41Å; A316-I319 PolarHBondContact O-N 2.99Å; A316-V320 PolarHBondContact O-N 2.97Å
317	V	85.6	Confident	86.6	Confident	61 Å²	61	50.2 Å²	50.2	37%	0.37	28%	0.283	S	S	.	.	H	α-helix	trans	-60.7	-52.4	-177.3	-179.6	0	0	0	0	112.8	V191 F314 L315 I319 V320 P321	V191-V317 HydrophobicContact CG1-CG2 4.43Å; F314-V317 PolarHBondContact O-N 2.85Å; L315-V317 VanDerWaalsContact C-N 3.33Å; V317-I319 PolarHBondContact O-N 3.33Å; V317-V320 PolarHBondContact O-N 3.32Å; V317-P321 WeakPolarHBondContact O-CD 3.43Å
318	P	87.8	Confident	86.7	Confident	62 Å²	62	54.7 Å²	54.7	40%	0.403	31%	0.306	S	S	.	.	H	α-helix	trans	-69.5	-14.1	177	27.7	-36	0	0	0	114	F314 L315 P321 L383	F314-P318 WeakPolarHBondContact O-CD 3.31Å; L315-P318 WeakPolarHBondContact O-CD 3.43Å; L315-P318 WeakPolarHBondContact O-CG 3.1Å; P318-P321 WeakPolarHBondContact O-CD 2.93Å; P318-L383 HydrophobicContact CB-CD1 4.49Å; P318-L383 HydrophobicContact CB-CD2 4.26Å; P318-L383 HydrophobicContact CG-CD1 3.72Å; P318-L383 HydrophobicContact CG-CD2 3.77Å; P318-L383 HydrophobicContact CG-CG 4.42Å
319	I	89.9	Confident	87.1	Confident	13 Å²	13	59.3 Å²	59.3	7%	0.067	32%	0.321	C	S	.	.	H	α-helix	trans	-76.5	-35.8	176.2	-70.9	172.5	0	0	0	111.1	L315 A316 V317 I322 E323 L383 F386 Q390	L315-I319 WeakPolarHBondContact O-CD1 3.36Å; L315-I319 WeakPolarHBondContact O-CG1 3.42Å; A316-I319 WeakPolarHBondContact O-CB 3.41Å; A316-I319 PolarHBondContact O-N 2.99Å; V317-I319 PolarHBondContact O-N 3.33Å; I319-I322 WeakPolarHBondContact O-CA 3.39Å; I319-I322 VanDerWaalsContact O-CB 3.24Å; I319-I322 WeakPolarHBondContact O-CB 3.02Å; I319-I322 PolarHBondContact O-N 2.92Å; I319-E323 HydrophobicContact CG2-CG 3.91Å; I319-E323 VanDerWaalsContact CG2-OE1 3.31Å; I319-E323 WeakPolarHBondContact CG2-OE1 3.42Å; I319-E323 PolarHBondContact O-N 2.65Å; I319-E323 VanDerWaalsContact O-N 3.15Å; I319-L383 HydrophobicContact CD1-CD1 4.16Å; I319-L383 HydrophobicContact CG1-CD1 3.84Å; I319-F386 HydrophobicContact CD1-CB 3.94Å; I319-Q390 HydrophobicContact CG2-CB 4.22Å; I319-Q390 HydrophobicContact CG2-CG 3.73Å
320	V	89.5	Confident	87.6	Confident	17 Å²	17	54.5 Å²	54.5	10%	0.103	30%	0.301	C	S	.	.	H	α-helix	trans	-54.5	-43.8	-175.7	172.4	0	0	0	0	114.1	T183 F187 A316 V317 I322 E323 I324	T183-V320 HydrophobicContact CG2-CG1 4.47Å; F187-V320 HydrophobicContact CB-CG1 3.96Å; F187-V320 HydrophobicContact CD2-CB 4.03Å; F187-V320 HydrophobicContact CD2-CG1 3.59Å; F187-V320 HydrophobicContact CD2-CG2 3.87Å; F187-V320 HydrophobicContact CE2-CB 4.29Å; F187-V320 HydrophobicContact CE2-CG1 4.16Å; F187-V320 HydrophobicContact CE2-CG2 4.31Å; F187-V320 HydrophobicContact CG-CG1 3.79Å; A316-V320 PolarHBondContact O-N 2.97Å; V317-V320 PolarHBondContact O-N 3.32Å; V320-I322 PolarHBondContact O-N 2.81Å; V320-E323 WeakPolarHBondContact O-CB 3.32Å; V320-E323 PolarHBondContact O-N 2.94Å; V320-I324 HydrophobicContact CG1-CD1 3.82Å; V320-I324 HydrophobicContact CG1-CG1 4.34Å; V320-I324 PolarHBondContact O-N 3.46Å
321	P	90.9	Very high	88.2	Confident	67 Å²	67	50.1 Å²	50.1	44%	0.435	28%	0.277	S	S	.	.	H	α-helix	trans	-56.4	-36.2	174	-27.6	35.5	0	0	0	113.5	V317 P318 I324 L325	V317-P321 WeakPolarHBondContact O-CD 3.43Å; P318-P321 WeakPolarHBondContact O-CD 2.93Å; P321-I324 PolarHBondContact O-N 3.41Å; P321-L325 VanDerWaalsContact O-CB 3.29Å; P321-L325 WeakPolarHBondContact O-CB 3.2Å; P321-L325 VanDerWaalsContact O-CG 3.24Å; P321-L325 WeakPolarHBondContact O-CG 3.31Å; P321-L325 PolarHBondContact O-N 2.85Å
322	I	90.6	Very high	88.6	Confident	48 Å²	48	53.1 Å²	53.1	25%	0.246	29%	0.29	C	S	.	.	H	α-helix	trans	-64.7	-44.6	175.3	-57.6	174.6	0	0	0	109.5	I319 V320 I324 L325 L326 I391	I319-I322 WeakPolarHBondContact O-CA 3.39Å; I319-I322 VanDerWaalsContact O-CB 3.24Å; I319-I322 WeakPolarHBondContact O-CB 3.02Å; I319-I322 PolarHBondContact O-N 2.92Å; V320-I322 PolarHBondContact O-N 2.81Å; I322-I324 VanDerWaalsContact C-N 3.26Å; I322-I324 PolarHBondContact O-N 3.45Å; I322-L325 PolarHBondContact O-N 3.17Å; I322-L326 HydrophobicContact CG2-CB 4.44Å; I322-L326 WeakPolarHBondContact O-CB 3.26Å; I322-L326 PolarHBondContact O-N 3.45Å; I322-I391 HydrophobicContact CG2-CG1 4Å
323	E	91.7	Very high	89	Confident	28 Å²	28	58.5 Å²	58.5	13%	0.131	31%	0.309	C	S	.	.	H	α-helix	trans	-62.6	-31.3	179.9	-61.5	-177.6	165.3	0	0	113.2	T183 I319 V320 P327 Q390 Y394	T183-E323 HydrophobicContact CG2-CB 3.85Å; I319-E323 HydrophobicContact CG2-CG 3.91Å; I319-E323 VanDerWaalsContact CG2-OE1 3.31Å; I319-E323 WeakPolarHBondContact CG2-OE1 3.42Å; I319-E323 PolarHBondContact O-N 2.65Å; I319-E323 VanDerWaalsContact O-N 3.15Å; V320-E323 WeakPolarHBondContact O-CB 3.32Å; V320-E323 PolarHBondContact O-N 2.94Å; E323-P327 WeakPolarHBondContact O-CD 3.34Å; E323-P327 VanDerWaalsContact O-CG 3.23Å; E323-P327 WeakPolarHBondContact O-CG 3.4Å; E323-Q390 PolarHBondContact OE1-NE2 3.38Å; E323-Y394 HydrophobicContact CB-CD1 4.45Å; E323-Y394 HydrophobicContact CB-CE1 3.68Å; E323-Y394 HydrophobicContact CB-CE2 4.09Å; E323-Y394 VanDerWaalsContact CB-CZ 3.5Å; E323-Y394 HydrophobicContact CG-CD2 4.27Å; E323-Y394 HydrophobicContact CG-CE1 4.09Å; E323-Y394 HydrophobicContact CG-CE2 3.52Å; E323-Y394 VanDerWaalsContact CG-CZ 3.43Å; E323-Y394 WeakPolarHBondContact CG-OH 3.49Å; E323-Y394 PolarHBondContact OE2-OH 3.2Å
324	I	92	Very high	89.7	Confident	39 Å²	39	55.4 Å²	55.4	20%	0.2	28%	0.283	C	S	.	.	H	α-helix	trans	-83.4	-44.1	177	-65	173.3	0	0	0	111.5	V180 T183 A184 V320 P321 I322	V180-I324 HydrophobicContact CG1-CG2 4.24Å; T183-I324 HydrophobicContact CG2-CG1 3.84Å; A184-I324 HydrophobicContact CB-CD1 4.05Å; V320-I324 HydrophobicContact CG1-CD1 3.82Å; V320-I324 HydrophobicContact CG1-CG1 4.34Å; V320-I324 PolarHBondContact O-N 3.46Å; P321-I324 PolarHBondContact O-N 3.41Å; I322-I324 VanDerWaalsContact C-N 3.26Å; I322-I324 PolarHBondContact O-N 3.45Å
325	L	93.5	Very high	90	Very high	91 Å²	91	51.1 Å²	51.1	48%	0.476	27%	0.266	S	S	.	.	H	α-helix	trans	-79.7	-38.2	-173.7	-67.5	176	0	0	0	112.8	P321 I322 L328 F329	P321-L325 VanDerWaalsContact O-CB 3.29Å; P321-L325 WeakPolarHBondContact O-CB 3.2Å; P321-L325 VanDerWaalsContact O-CG 3.24Å; P321-L325 WeakPolarHBondContact O-CG 3.31Å; P321-L325 PolarHBondContact O-N 2.85Å; I322-L325 PolarHBondContact O-N 3.17Å; L325-L328 HydrophobicContact CD2-CD1 4.38Å; L325-L328 WeakPolarHBondContact O-CB 3.32Å; L325-L328 PolarHBondContact O-N 3.34Å; L325-L328 VanDerWaalsContact O-N 3.1Å; L325-F329 HydrophobicContact CB-CE2 4.32Å; L325-F329 WeakPolarHBondContact O-CD2 3.18Å; L325-F329 PolarHBondContact O-N 3.24Å
326	L	93.8	Very high	90.2	Very high	26 Å²	26	51.4 Å²	51.4	14%	0.136	27%	0.273	C	S	.	.	H	α-helix	trans	-57.9	-47.7	-175.3	174.7	68.9	0	0	0	113	I322 L328 F329 I330 I391	I322-L326 HydrophobicContact CG2-CB 4.44Å; I322-L326 WeakPolarHBondContact O-CB 3.26Å; I322-L326 PolarHBondContact O-N 3.45Å; L326-L328 PolarHBondContact O-N 3.45Å; L326-F329 PolarHBondContact O-N 3.44Å; L326-I330 HydrophobicContact CD1-CG2 3.85Å; L326-I330 HydrophobicContact CG-CG2 4.41Å; L326-I330 WeakPolarHBondContact O-CG1 3.44Å; L326-I330 PolarHBondContact O-N 2.83Å; L326-I391 HydrophobicContact CD1-CG2 4.37Å; L326-I391 HydrophobicContact CD2-CB 4.19Å; L326-I391 HydrophobicContact CD2-CG1 4.25Å; L326-I391 HydrophobicContact CD2-CG2 4.14Å
327	P	93	Very high	90.6	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-55.5	-31.6	176.4	-27.2	36.1	0	0	0	114.1	T176 V179 V180 E323 G331 Y394 V398	T176-P327 HydrophobicContact CG2-CB 4.11Å; T176-P327 WeakPolarHBondContact CG2-O 3.35Å; T176-P327 PolarHBondContact OG1-O 3.47Å; V179-P327 HydrophobicContact CB-CG 4.21Å; V179-P327 HydrophobicContact CG1-CB 4.45Å; V179-P327 HydrophobicContact CG1-CG 3.65Å; V180-P327 HydrophobicContact CG2-CB 3.78Å; V180-P327 HydrophobicContact CG2-CG 4.28Å; E323-P327 WeakPolarHBondContact O-CD 3.34Å; E323-P327 VanDerWaalsContact O-CG 3.23Å; E323-P327 WeakPolarHBondContact O-CG 3.4Å; P327-G331 WeakPolarHBondContact O-CA 3.28Å; P327-G331 PolarHBondContact O-N 2.84Å; P327-Y394 HydrophobicContact CG-CD1 4.14Å; P327-V398 HydrophobicContact CB-CG2 4.09Å; P327-V398 HydrophobicContact CG-CG2 4.1Å
328	L	92.3	Very high	90.9	Very high	99 Å²	99	56.2 Å²	56.2	52%	0.518	28%	0.284	S	S	.	.	H	α-helix	trans	-67.5	-37.6	177.3	-58.5	174.7	0	0	0	111.4	T176 V180 L325 L326	T176-L328 HydrophobicContact CG2-CD2 4.1Å; V180-L328 HydrophobicContact CG1-CD2 4.41Å; V180-L328 HydrophobicContact CG2-CD2 3.79Å; V180-L328 HydrophobicContact CG2-CG 4.04Å; L325-L328 HydrophobicContact CD2-CD1 4.38Å; L325-L328 WeakPolarHBondContact O-CB 3.32Å; L325-L328 PolarHBondContact O-N 3.34Å; L325-L328 VanDerWaalsContact O-N 3.1Å; L326-L328 PolarHBondContact O-N 3.45Å
329	F	92	Very high	91.3	Very high	147 Å²	147	53.3 Å²	53.3	65%	0.645	27%	0.265	S	S	*	.	H	α-helix	trans	-76.6	-37.2	177.8	-70.2	-72.1	0	0	0	113.1	L325 L326	L325-F329 HydrophobicContact CB-CE2 4.32Å; L325-F329 WeakPolarHBondContact O-CD2 3.18Å; L325-F329 PolarHBondContact O-N 3.24Å; L326-F329 PolarHBondContact O-N 3.44Å
330	I	92.1	Very high	91.6	Very high	18 Å²	18	52.7 Å²	52.7	9%	0.092	26%	0.262	C	S	.	.	H	α-helix	trans	-87.3	-13.2	-179	68.9	170	0	0	0	113.7	L326 K332 Y333 T334 V398	L326-I330 HydrophobicContact CD1-CG2 3.85Å; L326-I330 HydrophobicContact CG-CG2 4.41Å; L326-I330 WeakPolarHBondContact O-CG1 3.44Å; L326-I330 PolarHBondContact O-N 2.83Å; I330-K332 VanDerWaalsContact C-N 3.26Å; I330-K332 PolarHBondContact O-N 3.33Å; I330-Y333 PolarHBondContact O-N 3.09Å; I330-T334 PolarHBondContact O-N 3.46Å; I330-T334 VanDerWaalsContact O-N 3.08Å; I330-T334 PolarHBondContact O-OG1 3.22Å; I330-V398 HydrophobicContact CD1-CB 3.89Å; I330-V398 HydrophobicContact CD1-CG1 4.15Å; I330-V398 HydrophobicContact CD1-CG2 4.14Å; I330-V398 HydrophobicContact CG1-CG1 4.4Å
331	G	89.1	Confident	91.9	Very high	0 Å²	0	55 Å²	55	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-51.8	-42.3	-178.7	0	0	0	0	0	112.9	T176 P327 Y333 T334 A335	T176-G331 WeakPolarHBondContact OG1-CA 3.28Å; P327-G331 WeakPolarHBondContact O-CA 3.28Å; P327-G331 PolarHBondContact O-N 2.84Å; G331-Y333 VanDerWaalsContact C-N 3.27Å; G331-Y333 PolarHBondContact O-N 2.98Å; G331-T334 WeakPolarHBondContact CA-OG1 3.3Å; G331-T334 PolarHBondContact O-N 3.24Å; G331-T334 PolarHBondContact O-OG1 3.43Å; G331-T334 VanDerWaalsContact O-OG1 3.12Å; G331-A335 VanDerWaalsContact O-CB 3.23Å; G331-A335 WeakPolarHBondContact O-CB 3.33Å; G331-A335 PolarHBondContact O-N 2.8Å
332	K	89.5	Confident	92.2	Very high	130 Å²	130	53.1 Å²	53.1	57%	0.565	26%	0.261	S	S	*	.	H	α-helix	trans	-63.1	-28.2	177.5	65.6	-178.7	178.6	178.1	0	114.5	I330	I330-K332 VanDerWaalsContact C-N 3.26Å; I330-K332 PolarHBondContact O-N 3.33Å
333	Y	91.1	Very high	92.5	Very high	143 Å²	143	50.9 Å²	50.9	56%	0.561	25%	0.249	S	C	*	.	H	α-helix	trans	-87.1	-27.1	178.6	-59.3	-70.9	0	0	0	112	I330 G331	I330-Y333 PolarHBondContact O-N 3.09Å; G331-Y333 VanDerWaalsContact C-N 3.27Å; G331-Y333 PolarHBondContact O-N 2.98Å
334	T	92.2	Very high	92.8	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-89.6	-25.5	178.8	52.9	0	0	0	0	112.6	I330 G331 G336 P339 V342 V398	I330-T334 PolarHBondContact O-N 3.46Å; I330-T334 VanDerWaalsContact O-N 3.08Å; I330-T334 PolarHBondContact O-OG1 3.22Å; G331-T334 WeakPolarHBondContact CA-OG1 3.3Å; G331-T334 PolarHBondContact O-N 3.24Å; G331-T334 PolarHBondContact O-OG1 3.43Å; G331-T334 VanDerWaalsContact O-OG1 3.12Å; T334-G336 PolarHBondContact O-N 3.43Å; T334-P339 WeakPolarHBondContact O-CB 3.42Å; T334-V342 HydrophobicContact CG2-CB 4.17Å; T334-V342 HydrophobicContact CG2-CG1 4.21Å; T334-V342 HydrophobicContact CG2-CG2 4.02Å; T334-V398 HydrophobicContact CG2-CG1 4.16Å
335	A	89.2	Confident	93	Very high	11 Å²	11	55.4 Å²	55.4	9%	0.091	27%	0.268	C	S	.	.	S	Bend	trans	-72.4	-13.1	176.3	0	0	0	0	0	114.1	Y173 G331	Y173-A335 HydrophobicContact CD1-CB 4.06Å; Y173-A335 HydrophobicContact CD2-CB 3.64Å; Y173-A335 HydrophobicContact CE1-CB 3.91Å; Y173-A335 HydrophobicContact CE2-CB 3.46Å; Y173-A335 VanDerWaalsContact CE2-CB 3.46Å; Y173-A335 HydrophobicContact CG-CB 3.94Å; G331-A335 VanDerWaalsContact O-CB 3.23Å; G331-A335 WeakPolarHBondContact O-CB 3.33Å; G331-A335 PolarHBondContact O-N 2.8Å
336	G	88.2	Confident	93.2	Very high	24 Å²	24	51.5 Å²	51.5	25%	0.247	25%	0.248	C	C	.	.	S	Bend	trans	-67.5	178.1	177.7	0	0	0	0	0	113.9	T334 R338 Q406	T334-G336 PolarHBondContact O-N 3.43Å; G336-R338 PolarHBondContact O-N 2.99Å; G336-Q406 PolarHBondContact O-NE2 3.34Å
337	P	88	Confident	93.4	Very high	82 Å²	82	50.3 Å²	50.3	53%	0.532	24%	0.242	S	C	.	.	S	Bend	trans	-69.6	-11	-179.1	30.3	-36.5	0	0	0	114.2	P339	P337-P339 VanDerWaalsContact C-CD 3.48Å
338	R	93.2	Very high	93.6	Very high	136 Å²	136	51.6 Å²	51.6	51%	0.513	25%	0.25	S	S	.	.			trans	-129.3	66.3	-178.5	-65.5	-173.2	176.3	162.8	-0.6	111.8	G336 L340 D341 Q488	G336-R338 PolarHBondContact O-N 2.99Å; R338-L340 VanDerWaalsContact C-N 3.32Å; R338-L340 PolarHBondContact O-N 2.91Å; R338-D341 HydrophobicContact CB-CB 4.46Å; R338-D341 WeakPolarHBondContact CB-OD2 3.31Å; R338-D341 WeakPolarHBondContact CD-OD2 3.26Å; R338-D341 PolarHBondContact O-N 3.42Å; R338-Q488 HydrophobicContact CG-CB 4.45Å; R338-Q488 PolarHBondContact O-OE1 2.85Å
339	P	94.9	Very high	93.9	Very high	0 Å²	0	53.9 Å²	53.9	0%	0	25%	0.253	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59	-39.3	-179.5	21.5	-32.2	0	0	0	113.5	T334 P337 D341 V342 S399 A402 F403 Q488	T334-P339 WeakPolarHBondContact O-CB 3.42Å; P337-P339 VanDerWaalsContact C-CD 3.48Å; P339-D341 PolarHBondContact O-N 3.28Å; P339-V342 WeakPolarHBondContact O-CB 3.39Å; P339-V342 PolarHBondContact O-N 2.9Å; P339-V342 VanDerWaalsContact O-N 3.12Å; P339-S399 WeakPolarHBondContact O-CB 3.3Å; P339-A402 HydrophobicContact CB-CB 3.89Å; P339-F403 HydrophobicContact CB-CB 4.39Å; P339-F403 HydrophobicContact CG-CB 3.7Å; P339-F403 HydrophobicContact CG-CD2 3.78Å; P339-F403 HydrophobicContact CG-CG 4.23Å; P339-Q488 VanDerWaalsContact N-OE1 3.17Å
340	L	96.5	Very high	94.1	Very high	0 Å²	0	47.4 Å²	47.4	0%	0	23%	0.225	C	C	.	.	H	α-helix	trans	-72.8	-7.2	-175.7	-50.3	172.2	0	0	0	112.8	R338 V342 Y343 L344 F403 M484 Q488	R338-L340 VanDerWaalsContact C-N 3.32Å; R338-L340 PolarHBondContact O-N 2.91Å; L340-V342 PolarHBondContact O-N 2.91Å; L340-Y343 VanDerWaalsContact O-CB 3.26Å; L340-Y343 WeakPolarHBondContact O-CB 3.19Å; L340-Y343 PolarHBondContact O-N 3.26Å; L340-L344 VanDerWaalsContact O-CG 3.3Å; L340-L344 WeakPolarHBondContact O-CG 3.05Å; L340-L344 PolarHBondContact O-N 2.82Å; L340-F403 HydrophobicContact CD1-CB 4.34Å; L340-F403 HydrophobicContact CD1-CD1 3.78Å; L340-F403 HydrophobicContact CD1-CD2 3.88Å; L340-F403 HydrophobicContact CD1-CE1 3.97Å; L340-F403 HydrophobicContact CD1-CE2 4.07Å; L340-F403 HydrophobicContact CD1-CG 3.72Å; L340-F403 HydrophobicContact CD1-CZ 4.1Å; L340-F403 HydrophobicContact CD2-CB 3.71Å; L340-F403 HydrophobicContact CD2-CD1 4.37Å; L340-F403 HydrophobicContact CD2-CG 4.02Å; L340-F403 HydrophobicContact CG-CB 3.96Å; L340-F403 HydrophobicContact CG-CD1 4.34Å; L340-F403 HydrophobicContact CG-CD2 4.04Å; L340-F403 HydrophobicContact CG-CG 3.85Å; L340-M484 HydrophobicContact CB-CE 4.43Å; L340-M484 HydrophobicContact CB-CG 3.9Å; L340-M484 HydrophobicContact CB-SD 4.36Å; L340-M484 HydrophobicContact CD1-CG 3.46Å; L340-M484 VanDerWaalsContact CD1-CG 3.46Å; L340-M484 HydrophobicContact CD1-SD 3.79Å; L340-M484 HydrophobicContact CD2-SD 4.28Å; L340-M484 HydrophobicContact CG-CG 4.21Å; L340-M484 HydrophobicContact CG-SD 4.37Å; L340-Q488 VanDerWaalsContact CB-CD 3.48Å; L340-Q488 HydrophobicContact CB-CG 4.04Å; L340-Q488 HydrophobicContact CD1-CG 3.81Å; L340-Q488 HydrophobicContact CG-CG 4.09Å
341	D	96.5	Very high	94.4	Very high	66 Å²	66	46.6 Å²	46.6	35%	0.353	22%	0.22	S	C	.	.	H	α-helix	trans	-64.4	-34.5	168.5	-71.2	-5.9	0	0	0	110.7	R338 P339 L344 K345 Q488	R338-D341 HydrophobicContact CB-CB 4.46Å; R338-D341 WeakPolarHBondContact CB-OD2 3.31Å; R338-D341 WeakPolarHBondContact CD-OD2 3.26Å; R338-D341 PolarHBondContact O-N 3.42Å; P339-D341 PolarHBondContact O-N 3.28Å; D341-L344 PolarHBondContact O-N 3.36Å; D341-K345 VanDerWaalsContact O-CB 3.28Å; D341-K345 WeakPolarHBondContact O-CB 3.44Å; D341-K345 PolarHBondContact O-N 2.95Å; D341-Q488 PolarHBondContact OD1-NE2 2.69Å
342	V	96.5	Very high	94.8	Very high	28 Å²	28	49.9 Å²	49.9	17%	0.17	24%	0.236	C	C	.	.	H	α-helix	trans	-65.8	-42.5	172.1	178.9	0	0	0	0	110.5	T334 P339 L340 L344 K345 A346 C395	T334-V342 HydrophobicContact CG2-CB 4.17Å; T334-V342 HydrophobicContact CG2-CG1 4.21Å; T334-V342 HydrophobicContact CG2-CG2 4.02Å; P339-V342 WeakPolarHBondContact O-CB 3.39Å; P339-V342 PolarHBondContact O-N 2.9Å; P339-V342 VanDerWaalsContact O-N 3.12Å; L340-V342 PolarHBondContact O-N 2.91Å; V342-L344 PolarHBondContact O-N 3.47Å; V342-K345 PolarHBondContact O-N 3.18Å; V342-A346 WeakPolarHBondContact O-CB 3.26Å; V342-A346 PolarHBondContact O-N 2.99Å; V342-C395 HydrophobicContact CG1-CB 4.08Å
343	Y	97.4	Very high	95.1	Very high	1 Å²	1	44.8 Å²	44.8	0%	0.004	22%	0.215	C	C	.	.	H	α-helix	trans	-54.4	-55.6	173.6	-170.9	-65.8	0	0	0	110.4	A287 L340 K345 A346 Y347 I396 S399 Q400 W476 M484	A287-Y343 WeakPolarHBondContact CB-OH 3.11Å; L340-Y343 VanDerWaalsContact O-CB 3.26Å; L340-Y343 WeakPolarHBondContact O-CB 3.19Å; L340-Y343 PolarHBondContact O-N 3.26Å; Y343-K345 VanDerWaalsContact C-N 3.27Å; Y343-K345 PolarHBondContact O-N 2.87Å; Y343-A346 PolarHBondContact O-N 2.84Å; Y343-Y347 HydrophobicContact CD1-CD2 4.22Å; Y343-Y347 AromaticContact CE1-CD2 3.51Å; Y343-Y347 HydrophobicContact CE1-CD2 3.51Å; Y343-Y347 HydrophobicContact CE1-CE2 4.1Å; Y343-Y347 HydrophobicContact CE1-CG 4.45Å; Y343-Y347 WeakPolarHBondContact O-CB 3.29Å; Y343-Y347 PolarHBondContact O-N 2.79Å; Y343-I396 HydrophobicContact CD1-CG1 4.28Å; Y343-I396 HydrophobicContact CD2-CB 4.19Å; Y343-I396 HydrophobicContact CD2-CG1 4.22Å; Y343-I396 HydrophobicContact CD2-CG2 3.79Å; Y343-I396 HydrophobicContact CE1-CG1 4.4Å; Y343-I396 HydrophobicContact CE2-CB 4.26Å; Y343-I396 HydrophobicContact CE2-CG1 4.37Å; Y343-I396 HydrophobicContact CE2-CG2 3.41Å; Y343-I396 VanDerWaalsContact CE2-CG2 3.41Å; Y343-I396 HydrophobicContact CG-CG1 4.17Å; Y343-S399 WeakPolarHBondContact CB-OG 3.34Å; Y343-S399 PolarHBondContact N-OG 3.48Å; Y343-Q400 HydrophobicContact CD2-CB 4.48Å; Y343-W476 AromaticContact CE1-CH2 3.83Å; Y343-W476 HydrophobicContact CE1-CH2 3.83Å; Y343-W476 HydrophobicContact CE1-CZ3 4.12Å; Y343-M484 HydrophobicContact CD1-CE 3.06Å; Y343-M484 HydrophobicContact CD2-CE 3.87Å; Y343-M484 HydrophobicContact CE1-CE 3.34Å; Y343-M484 HydrophobicContact CE2-CE 4.06Å; Y343-M484 HydrophobicContact CG-CE 3.39Å
344	L	97.6	Very high	95.4	Very high	11 Å²	11	38 Å²	38	6%	0.058	19%	0.189	C	C	.	.	H	α-helix	trans	-66.8	-29.9	-174.9	-67.4	170.9	0	0	0	112.3	L340 D341 V342 P348 W476 L477 M484 R485	L340-L344 VanDerWaalsContact O-CG 3.3Å; L340-L344 WeakPolarHBondContact O-CG 3.05Å; L340-L344 PolarHBondContact O-N 2.82Å; D341-L344 PolarHBondContact O-N 3.36Å; V342-L344 PolarHBondContact O-N 3.47Å; L344-P348 WeakPolarHBondContact O-CD 3.32Å; L344-W476 HydrophobicContact CD2-CZ3 4.42Å; L344-L477 HydrophobicContact CD2-CD1 3.99Å; L344-M484 HydrophobicContact CD2-CB 4.43Å; L344-M484 HydrophobicContact CD2-CE 3.87Å; L344-M484 HydrophobicContact CG-CE 4.16Å; L344-R485 HydrophobicContact CD1-CG 3.32Å
345	K	97.2	Very high	95.7	Very high	151 Å²	151	40.6 Å²	40.6	66%	0.657	20%	0.203	S	C	*	.	H	α-helix	trans	-73	-38.4	173.8	-171.4	174.3	-178.2	178.9	0	112.1	D341 V342 Y343 P348 Y349	D341-K345 VanDerWaalsContact O-CB 3.28Å; D341-K345 WeakPolarHBondContact O-CB 3.44Å; D341-K345 PolarHBondContact O-N 2.95Å; V342-K345 PolarHBondContact O-N 3.18Å; Y343-K345 VanDerWaalsContact C-N 3.27Å; Y343-K345 PolarHBondContact O-N 2.87Å; K345-P348 WeakPolarHBondContact O-CD 3.31Å; K345-Y349 WeakPolarHBondContact O-CD2 3.25Å; K345-Y349 VanDerWaalsContact O-CE2 3.23Å; K345-Y349 WeakPolarHBondContact O-CE2 3.46Å
346	A	97.3	Very high	96	Very high	9 Å²	9	41.7 Å²	41.7	7%	0.074	21%	0.212	C	C	.	.	H	α-helix	trans	-75.4	-29.1	178.5	0	0	0	0	0	113.1	V342 Y343 Y349 R350 C395 I396	V342-A346 WeakPolarHBondContact O-CB 3.26Å; V342-A346 PolarHBondContact O-N 2.99Å; Y343-A346 PolarHBondContact O-N 2.84Å; A346-Y349 PolarHBondContact O-N 3.08Å; A346-R350 PolarHBondContact O-N 2.84Å; A346-C395 HydrophobicContact CB-CB 3.58Å; A346-I396 HydrophobicContact CB-CG1 4.2Å
347	Y	98.1	Very high	96.4	Very high	1 Å²	1	40.9 Å²	40.9	0%	0.004	20%	0.201	C	C	.	.	H	α-helix	trans	-53.1	-50.8	-176.3	-162.7	-87.4	0	0	0	115.5	A287 F291 Y343 Y349 R350 N351 I396 G473 W476 L477	A287-Y347 WeakPolarHBondContact O-CE2 3.5Å; A287-Y347 PolarHBondContact O-OH 3.47Å; F291-Y347 HydrophobicContact CE2-CD2 4.08Å; F291-Y347 AromaticContact CE2-CE2 3.63Å; F291-Y347 HydrophobicContact CE2-CE2 3.63Å; F291-Y347 HydrophobicContact CZ-CD1 4.44Å; F291-Y347 AromaticContact CZ-CD2 3.72Å; F291-Y347 HydrophobicContact CZ-CD2 3.72Å; F291-Y347 HydrophobicContact CZ-CE1 4.14Å; F291-Y347 AromaticContact CZ-CE2 3.39Å; F291-Y347 HydrophobicContact CZ-CE2 3.39Å; F291-Y347 HydrophobicContact CZ-CG 4.25Å; F291-Y347 AromaticContact CZ-CZ 3.63Å; Y343-Y347 HydrophobicContact CD1-CD2 4.22Å; Y343-Y347 AromaticContact CE1-CD2 3.51Å; Y343-Y347 HydrophobicContact CE1-CD2 3.51Å; Y343-Y347 HydrophobicContact CE1-CE2 4.1Å; Y343-Y347 HydrophobicContact CE1-CG 4.45Å; Y343-Y347 WeakPolarHBondContact O-CB 3.29Å; Y343-Y347 PolarHBondContact O-N 2.79Å; Y347-Y349 VanDerWaalsContact C-N 3.32Å; Y347-Y349 PolarHBondContact O-N 2.65Å; Y347-R350 WeakPolarHBondContact O-CB 3.41Å; Y347-R350 PolarHBondContact O-N 3.45Å; Y347-N351 WeakPolarHBondContact O-CB 3.42Å; Y347-N351 PolarHBondContact O-N 3.21Å; Y347-I396 HydrophobicContact CD2-CD1 4.34Å; Y347-G473 WeakPolarHBondContact CE1-O 3.42Å; Y347-W476 HydrophobicContact CD1-CE3 4.28Å; Y347-W476 HydrophobicContact CD1-CZ3 4.42Å; Y347-W476 HydrophobicContact CD2-CE3 4.27Å; Y347-W476 AromaticContact CD2-CZ3 3.85Å; Y347-W476 HydrophobicContact CD2-CZ3 3.85Å; Y347-W476 AromaticContact CE1-CE3 3.72Å; Y347-W476 HydrophobicContact CE1-CE3 3.72Å; Y347-W476 HydrophobicContact CE1-CZ3 4.23Å; Y347-W476 HydrophobicContact CE2-CD2 4.44Å; Y347-W476 AromaticContact CE2-CE3 3.69Å; Y347-W476 HydrophobicContact CE2-CE3 3.69Å; Y347-W476 HydrophobicContact CE2-CH2 4.29Å; Y347-W476 AromaticContact CE2-CZ3 3.61Å; Y347-W476 HydrophobicContact CE2-CZ3 3.61Å; Y347-W476 HydrophobicContact CG-CZ3 4.23Å; Y347-W476 AromaticContact CZ-CE3 3.38Å; Y347-W476 AromaticContact CZ-CZ3 3.82Å; Y347-L477 HydrophobicContact CD1-CB 4.21Å; Y347-L477 HydrophobicContact CD1-CD1 4.09Å; Y347-L477 HydrophobicContact CD1-CD2 4.49Å; Y347-L477 HydrophobicContact CD1-CG 4.5Å; Y347-L477 HydrophobicContact CE1-CB 4.36Å; Y347-L477 HydrophobicContact CG-CD1 4.42Å
348	P	97.7	Very high	96.9	Very high	27 Å²	27	37.2 Å²	37.2	18%	0.175	18%	0.178	C	C	.	.	H	α-helix	trans	-62.8	-36.8	179.3	23.7	-34.6	0	0	0	112.8	L344 K345 N351 M352 W474 L477	L344-P348 WeakPolarHBondContact O-CD 3.32Å; K345-P348 WeakPolarHBondContact O-CD 3.31Å; P348-N351 WeakPolarHBondContact O-CB 3.24Å; P348-N351 PolarHBondContact O-N 2.9Å; P348-M352 WeakPolarHBondContact O-CG 3.49Å; P348-M352 PolarHBondContact O-N 3.32Å; P348-W474 HydrophobicContact CB-CH2 3.81Å; P348-W474 HydrophobicContact CB-CZ2 4.44Å; P348-W474 HydrophobicContact CB-CZ3 4.23Å; P348-L477 HydrophobicContact CB-CD2 4.26Å; P348-L477 HydrophobicContact CG-CD2 4.46Å
349	Y	97.7	Very high	97	Very high	147 Å²	147	33.5 Å²	33.5	58%	0.576	18%	0.176	S	C	*	.	H	α-helix	trans	-66.1	-44.7	175.4	-58.7	-78.8	0	0	0	111.2	K345 A346 Y347 N351 M352 L353	K345-Y349 WeakPolarHBondContact O-CD2 3.25Å; K345-Y349 VanDerWaalsContact O-CE2 3.23Å; K345-Y349 WeakPolarHBondContact O-CE2 3.46Å; A346-Y349 PolarHBondContact O-N 3.08Å; Y347-Y349 VanDerWaalsContact C-N 3.32Å; Y347-Y349 PolarHBondContact O-N 2.65Å; Y349-N351 VanDerWaalsContact C-N 3.27Å; Y349-N351 PolarHBondContact O-N 3.31Å; Y349-M352 PolarHBondContact O-N 2.86Å; Y349-L353 VanDerWaalsContact O-CG 3.28Å; Y349-L353 WeakPolarHBondContact O-CG 3.26Å; Y349-L353 PolarHBondContact O-N 3.3Å
350	R	97	Very high	97.1	Very high	11 Å²	11	33.6 Å²	33.6	4%	0.042	18%	0.177	C	C	.	.	H	α-helix	trans	-57	-43.1	173.3	-176.3	67.6	-177.7	-151.7	-1.8	111.3	F291 D295 A346 Y347 L353 Q389 T392 S393 I396	F291-R350 HydrophobicContact CD1-CG 3.74Å; F291-R350 HydrophobicContact CD2-CG 3.97Å; F291-R350 HydrophobicContact CE1-CB 3.97Å; F291-R350 HydrophobicContact CE1-CG 3.48Å; F291-R350 VanDerWaalsContact CE1-CG 3.48Å; F291-R350 HydrophobicContact CE2-CB 4.49Å; F291-R350 HydrophobicContact CE2-CG 3.71Å; F291-R350 HydrophobicContact CG-CG 3.99Å; F291-R350 HydrophobicContact CZ-CB 3.87Å; F291-R350 HydrophobicContact CZ-CG 3.45Å; F291-R350 VanDerWaalsContact CZ-CG 3.45Å; D295-R350 IonicContact OD1-CZ 2.7Å; D295-R350 IonicContact OD1-NH2 2.71Å; D295-R350 PolarHBondContact OD1-NH2 3.35Å; D295-R350 IonicContact OD2-NH2 2.67Å; D295-R350 PolarHBondContact OD2-NH2 2.89Å; A346-R350 PolarHBondContact O-N 2.84Å; Y347-R350 WeakPolarHBondContact O-CB 3.41Å; Y347-R350 PolarHBondContact O-N 3.45Å; R350-L353 PolarHBondContact O-N 2.82Å; R350-Q389 VanDerWaalsContact CZ-CG 3.41Å; R350-Q389 PolarHBondContact NH1-O 2.98Å; R350-Q389 VanDerWaalsContact NH2-NE2 3.17Å; R350-T392 WeakPolarHBondContact CD-OG1 3.04Å; R350-S393 PolarHBondContact NH1-OG 3.13Å; R350-S393 VanDerWaalsContact NH1-OG 3.07Å; R350-I396 HydrophobicContact CB-CD1 4.13Å; R350-I396 HydrophobicContact CG-CD1 4.2Å
351	N	97.4	Very high	97.1	Very high	1 Å²	1	33.9 Å²	33.9	1%	0.005	18%	0.178	C	C	.	.	H	α-helix	trans	-62.6	-48.7	179.5	-160.8	37.3	0	0	0	111.9	F291 Y347 P348 Y349 L353 S354 V470	F291-N351 HydrophobicContact CE1-CB 4.02Å; Y347-N351 WeakPolarHBondContact O-CB 3.42Å; Y347-N351 PolarHBondContact O-N 3.21Å; P348-N351 WeakPolarHBondContact O-CB 3.24Å; P348-N351 PolarHBondContact O-N 2.9Å; Y349-N351 VanDerWaalsContact C-N 3.27Å; Y349-N351 PolarHBondContact O-N 3.31Å; N351-L353 VanDerWaalsContact C-N 3.34Å; N351-L353 PolarHBondContact O-N 3.3Å; N351-S354 VanDerWaalsContact O-CB 3.26Å; N351-S354 WeakPolarHBondContact O-CB 3.46Å; N351-S354 PolarHBondContact O-N 2.91Å; N351-S354 PolarHBondContact O-OG 3.32Å; N351-V470 PolarHBondContact ND2-O 2.8Å; N351-V470 WeakPolarHBondContact OD1-CA 3.29Å
352	M	97.3	Very high	97	Very high	68 Å²	68	39.8 Å²	39.8	34%	0.335	20%	0.196	S	C	.	.	H	α-helix	trans	-67.5	-30.9	178.9	-65.8	-61.4	89.7	0	0	113.6	P348 Y349 S354 L355 A356 V470 W474	P348-M352 WeakPolarHBondContact O-CG 3.49Å; P348-M352 PolarHBondContact O-N 3.32Å; Y349-M352 PolarHBondContact O-N 2.86Å; M352-S354 PolarHBondContact O-N 3.32Å; M352-L355 HydrophobicContact CE-CD1 4.31Å; M352-L355 WeakPolarHBondContact O-CB 3.27Å; M352-L355 PolarHBondContact O-N 3.49Å; M352-L355 HydrophobicContact SD-CD1 4.23Å; M352-A356 PolarHBondContact O-N 2.85Å; M352-V470 HydrophobicContact CE-CB 4.5Å; M352-V470 HydrophobicContact CE-CG1 3.34Å; M352-V470 HydrophobicContact CE-CG2 4.46Å; M352-W474 HydrophobicContact CE-CZ2 4.11Å; M352-W474 HydrophobicContact CG-CZ2 4.45Å; M352-W474 HydrophobicContact SD-CZ2 4.25Å
353	L	97.1	Very high	97	Very high	23 Å²	23	44 Å²	44	12%	0.12	21%	0.209	C	C	.	.	H	α-helix	trans	-61.9	-23.2	174.4	-76.2	165.5	0	0	0	112.8	Y349 R350 N351 L355 A356 F357 L388 T392	Y349-L353 VanDerWaalsContact O-CG 3.28Å; Y349-L353 WeakPolarHBondContact O-CG 3.26Å; Y349-L353 PolarHBondContact O-N 3.3Å; R350-L353 PolarHBondContact O-N 2.82Å; N351-L353 VanDerWaalsContact C-N 3.34Å; N351-L353 PolarHBondContact O-N 3.3Å; L353-L355 VanDerWaalsContact C-N 3.28Å; L353-L355 PolarHBondContact O-N 2.8Å; L353-A356 HydrophobicContact CD2-CB 4.35Å; L353-A356 WeakPolarHBondContact O-CB 3.5Å; L353-A356 PolarHBondContact O-N 3.35Å; L353-A356 VanDerWaalsContact O-N 3.11Å; L353-F357 VanDerWaalsContact O-CD2 3.28Å; L353-F357 WeakPolarHBondContact O-CD2 3.44Å; L353-F357 PolarHBondContact O-N 3.45Å; L353-L388 HydrophobicContact CD1-CB 4.07Å; L353-L388 WeakPolarHBondContact CD1-O 3.3Å; L353-L388 HydrophobicContact CD2-CB 3.87Å; L353-L388 HydrophobicContact CD2-CD1 4.34Å; L353-T392 HydrophobicContact CD1-CG2 4.02Å
354	S	97.1	Very high	96.9	Very high	2 Å²	2	44 Å²	44	1%	0.014	21%	0.209	C	C	.	.	H	α-helix	trans	-61.1	-37.5	171.3	-50.6	0	0	0	0	111.9	N351 M352 F357 A358 I466	N351-S354 VanDerWaalsContact O-CB 3.26Å; N351-S354 WeakPolarHBondContact O-CB 3.46Å; N351-S354 PolarHBondContact O-N 2.91Å; N351-S354 PolarHBondContact O-OG 3.32Å; M352-S354 PolarHBondContact O-N 3.32Å; S354-F357 PolarHBondContact O-N 3.3Å; S354-A358 PolarHBondContact O-N 2.92Å; S354-I466 WeakPolarHBondContact O-CG2 3.2Å
355	L	97.3	Very high	96.7	Very high	54 Å²	54	46.8 Å²	46.8	28%	0.283	23%	0.228	S	C	.	.	H	α-helix	trans	-69	-35.3	173.4	-62.1	177.8	0	0	0	111.7	M352 L353 F357 A358 A359 I466 F467 V470	M352-L355 HydrophobicContact CE-CD1 4.31Å; M352-L355 WeakPolarHBondContact O-CB 3.27Å; M352-L355 PolarHBondContact O-N 3.49Å; M352-L355 HydrophobicContact SD-CD1 4.23Å; L353-L355 VanDerWaalsContact C-N 3.28Å; L353-L355 PolarHBondContact O-N 2.8Å; L355-F357 VanDerWaalsContact C-N 3.3Å; L355-F357 PolarHBondContact O-N 3.44Å; L355-A358 PolarHBondContact O-N 2.96Å; L355-A359 WeakPolarHBondContact O-CB 3.47Å; L355-A359 PolarHBondContact O-N 3.23Å; L355-I466 HydrophobicContact CD2-CG2 4.07Å; L355-F467 HydrophobicContact CD2-CD1 3.8Å; L355-F467 HydrophobicContact CD2-CE1 3.69Å; L355-F467 HydrophobicContact CD2-CZ 4.47Å; L355-V470 HydrophobicContact CD1-CG1 4.38Å; L355-V470 HydrophobicContact CD2-CG2 3.87Å; L355-V470 HydrophobicContact CG-CG2 3.85Å
356	A	96.5	Very high	96.6	Very high	34 Å²	34	43.5 Å²	43.5	28%	0.281	22%	0.224	S	C	.	.	H	α-helix	trans	-62.5	-38.9	174.4	0	0	0	0	0	111.3	M352 L353 A359 A360 I385	M352-A356 PolarHBondContact O-N 2.85Å; L353-A356 HydrophobicContact CD2-CB 4.35Å; L353-A356 WeakPolarHBondContact O-CB 3.5Å; L353-A356 PolarHBondContact O-N 3.35Å; L353-A356 VanDerWaalsContact O-N 3.11Å; A356-A359 PolarHBondContact O-N 2.03Å; A356-A360 VanDerWaalsContact O-CB 3.28Å; A356-A360 WeakPolarHBondContact O-CB 3.28Å; A356-A360 PolarHBondContact O-N 2.99Å; A356-I385 HydrophobicContact CB-CG2 4.28Å
357	F	97.1	Very high	96.4	Very high	6 Å²	6	46 Å²	46	3%	0.026	23%	0.231	C	C	.	.	H	α-helix	trans	-64.3	-45.8	171.1	-75.7	-60.4	0	0	0	112.6	A294 T298 L353 S354 L355 A359 A360 I361 I385 F386 Q389	A294-F357 HydrophobicContact CB-CD2 4.38Å; T298-F357 HydrophobicContact CG2-CB 4.08Å; T298-F357 HydrophobicContact CG2-CD1 3.62Å; T298-F357 HydrophobicContact CG2-CE1 4.31Å; T298-F357 HydrophobicContact CG2-CG 3.98Å; L353-F357 VanDerWaalsContact O-CD2 3.28Å; L353-F357 WeakPolarHBondContact O-CD2 3.44Å; L353-F357 PolarHBondContact O-N 3.45Å; S354-F357 PolarHBondContact O-N 3.3Å; L355-F357 VanDerWaalsContact C-N 3.3Å; L355-F357 PolarHBondContact O-N 3.44Å; F357-A359 VanDerWaalsContact C-N 3.33Å; F357-A359 PolarHBondContact O-N 3.22Å; F357-A360 PolarHBondContact O-N 3.04Å; F357-I361 VanDerWaalsContact O-CG1 3.27Å; F357-I361 WeakPolarHBondContact O-CG1 3.1Å; F357-I361 PolarHBondContact O-N 3.41Å; F357-I385 HydrophobicContact CD1-CG2 3.79Å; F357-I385 HydrophobicContact CD2-CG2 4.44Å; F357-I385 HydrophobicContact CE1-CB 4.25Å; F357-I385 HydrophobicContact CE1-CG2 3.43Å; F357-I385 VanDerWaalsContact CE1-CG2 3.43Å; F357-I385 HydrophobicContact CE2-CG2 4.12Å; F357-I385 HydrophobicContact CG-CG2 4.27Å; F357-I385 HydrophobicContact CZ-CG2 3.6Å; F357-F386 HydrophobicContact CE1-CD1 4.26Å; F357-F386 AromaticContact CE1-CD2 3.93Å; F357-F386 HydrophobicContact CE1-CD2 3.93Å; F357-F386 HydrophobicContact CE1-CE1 4.13Å; F357-F386 AromaticContact CE1-CE2 3.8Å; F357-F386 HydrophobicContact CE1-CE2 3.8Å; F357-F386 HydrophobicContact CE1-CG 4.17Å; F357-F386 AromaticContact CE1-CZ 3.9Å; F357-F386 HydrophobicContact CE1-CZ 3.9Å; F357-F386 HydrophobicContact CZ-CD1 4.13Å; F357-F386 HydrophobicContact CZ-CD2 4.48Å; F357-F386 HydrophobicContact CZ-CE1 4.24Å; F357-F386 HydrophobicContact CZ-CG 4.26Å; F357-F386 HydrophobicContact CZ-CZ 4.46Å; F357-Q389 HydrophobicContact CE2-CB 3.82Å; F357-Q389 HydrophobicContact CE2-CG 3.86Å; F357-Q389 HydrophobicContact CZ-CB 3.84Å; F357-Q389 HydrophobicContact CZ-CG 4.17Å
358	A	97.1	Very high	96.2	Very high	6 Å²	6	50 Å²	50	5%	0.05	25%	0.249	C	C	.	.	H	α-helix	trans	-56.5	-47	174.9	0	0	0	0	0	112	S354 L355 A360 I361 W362 Y463 I466	S354-A358 PolarHBondContact O-N 2.92Å; L355-A358 PolarHBondContact O-N 2.96Å; A358-A360 PolarHBondContact O-N 3.05Å; A358-I361 PolarHBondContact O-N 2.7Å; A358-W362 WeakPolarHBondContact O-CB 3.35Å; A358-W362 PolarHBondContact O-N 3.27Å; A358-Y463 HydrophobicContact CB-CD1 4Å; A358-Y463 HydrophobicContact CB-CE1 4.25Å; A358-Y463 WeakPolarHBondContact O-CE1 3.16Å; A358-I466 HydrophobicContact CB-CB 4.42Å; A358-I466 HydrophobicContact CB-CG2 3.89Å
359	A	96.8	Very high	95.8	Very high	57 Å²	57	51 Å²	51	47%	0.471	26%	0.255	S	S	.	.	H	α-helix	trans	-61.6	-42.3	176.1	0	0	0	0	0	112.2	L355 A356 F357 W362 W363	L355-A359 WeakPolarHBondContact O-CB 3.47Å; L355-A359 PolarHBondContact O-N 3.23Å; A356-A359 PolarHBondContact O-N 2.03Å; F357-A359 VanDerWaalsContact C-N 3.33Å; F357-A359 PolarHBondContact O-N 3.22Å; A359-W362 PolarHBondContact O-N 3.21Å; A359-W363 VanDerWaalsContact O-CB 3.31Å; A359-W363 WeakPolarHBondContact O-CB 3.23Å; A359-W363 PolarHBondContact O-N 3.03Å
360	A	96.1	Very high	95.3	Very high	3 Å²	3	51 Å²	51	3%	0.025	27%	0.273	C	S	.	.	H	α-helix	trans	-64.5	-41.9	177.6	0	0	0	0	0	112.7	A356 F357 A358 W363 T364 F381 I382 I385	A356-A360 VanDerWaalsContact O-CB 3.28Å; A356-A360 WeakPolarHBondContact O-CB 3.28Å; A356-A360 PolarHBondContact O-N 2.99Å; F357-A360 PolarHBondContact O-N 3.04Å; A358-A360 PolarHBondContact O-N 3.05Å; A360-W363 PolarHBondContact O-N 3.21Å; A360-T364 WeakPolarHBondContact O-CB 3.27Å; A360-T364 PolarHBondContact O-N 2.86Å; A360-T364 PolarHBondContact O-OG1 3.05Å; A360-F381 HydrophobicContact CB-CE1 3.78Å; A360-F381 HydrophobicContact CB-CZ 4.15Å; A360-I382 HydrophobicContact CB-CD1 4.15Å; A360-I385 HydrophobicContact CB-CD1 3.68Å
361	I	96.1	Very high	94.8	Very high	5 Å²	5	54.8 Å²	54.8	3%	0.026	30%	0.301	C	S	.	.	H	α-helix	trans	-63.9	-46.6	175.4	-65.7	-62.2	0	0	0	110.4	T298 K301 L302 L305 F357 A358 W363 T364 P365 Y462	T298-I361 HydrophobicContact CG2-CD1 4.09Å; T298-I361 HydrophobicContact CG2-CG1 4.27Å; K301-I361 HydrophobicContact CB-CD1 3.96Å; K301-I361 HydrophobicContact CB-CG1 4.42Å; K301-I361 HydrophobicContact CB-CG2 4.13Å; L302-I361 HydrophobicContact CD2-CD1 3.44Å; L302-I361 VanDerWaalsContact CD2-CD1 3.44Å; L302-I361 HydrophobicContact CG-CD1 3.54Å; L305-I361 HydrophobicContact CD1-CG2 3.96Å; L305-I361 WeakPolarHBondContact CD1-O 3.44Å; F357-I361 VanDerWaalsContact O-CG1 3.27Å; F357-I361 WeakPolarHBondContact O-CG1 3.1Å; F357-I361 PolarHBondContact O-N 3.41Å; A358-I361 PolarHBondContact O-N 2.7Å; I361-W363 VanDerWaalsContact C-N 3.25Å; I361-W363 PolarHBondContact O-N 2.71Å; I361-T364 WeakPolarHBondContact O-CB 3.28Å; I361-T364 PolarHBondContact O-N 3.22Å; I361-P365 WeakPolarHBondContact O-CD 3.37Å; I361-Y462 HydrophobicContact CB-CE1 4.04Å; I361-Y462 HydrophobicContact CG1-CE1 3.9Å; I361-Y462 HydrophobicContact CG2-CD1 4.45Å; I361-Y462 HydrophobicContact CG2-CE1 4.1Å
362	W	95.7	Very high	94.3	Very high	190 Å²	190	56.1 Å²	56.1	72%	0.72	32%	0.315	S	S	*	.	H	α-helix	trans	-59.7	-37.1	176.5	179.8	80.3	0	0	0	112.5	A358 A359 P365 Y463	A358-W362 WeakPolarHBondContact O-CB 3.35Å; A358-W362 PolarHBondContact O-N 3.27Å; A359-W362 PolarHBondContact O-N 3.21Å; W362-P365 WeakPolarHBondContact O-CD 3.43Å; W362-Y463 VanDerWaalsContact CA-OH 3.26Å; W362-Y463 WeakPolarHBondContact CA-OH 3.05Å; W362-Y463 HydrophobicContact CB-CE1 4.11Å; W362-Y463 WeakPolarHBondContact CB-OH 3.47Å; W362-Y463 PolarHBondContact N-OH 3.41Å
363	W	95.7	Very high	93.9	Very high	118 Å²	118	61.9 Å²	61.9	45%	0.447	33%	0.333	S	S	.	.	H	α-helix	trans	-81.2	-24.2	-179	-162.3	13.3	0	0	0	113.4	A359 A360 I361 P365 S366 W367 F381	A359-W363 VanDerWaalsContact O-CB 3.31Å; A359-W363 WeakPolarHBondContact O-CB 3.23Å; A359-W363 PolarHBondContact O-N 3.03Å; A360-W363 PolarHBondContact O-N 3.21Å; I361-W363 VanDerWaalsContact C-N 3.25Å; I361-W363 PolarHBondContact O-N 2.71Å; W363-P365 VanDerWaalsContact C-CD 3.44Å; W363-S366 PolarHBondContact NE1-OG 3.03Å; W363-S366 PolarHBondContact O-N 3.32Å; W363-S366 PolarHBondContact O-OG 3.26Å; W363-W367 AromaticContact CD1-CD1 3.96Å; W363-W367 AromaticContact CD1-NE1 3.75Å; W363-W367 AromaticContact CD2-NE1 3.35Å; W363-W367 AromaticContact CE2-NE1 3.29Å; W363-W367 VanDerWaalsContact CE2-NE1 3.29Å; W363-W367 AromaticContact CE3-NE1 3.88Å; W363-W367 AromaticContact CG-NE1 3.65Å; W363-W367 AromaticContact CH2-CZ2 3.91Å; W363-W367 HydrophobicContact CH2-CZ2 3.91Å; W363-W367 HydrophobicContact CZ2-CZ2 4.02Å; W363-W367 AromaticContact CZ2-NE1 3.78Å; W363-W367 HydrophobicContact CZ3-CZ2 4.2Å; W363-W367 AromaticContact NE1-NE1 3.51Å; W363-F381 HydrophobicContact CE3-CE1 4.44Å; W363-F381 HydrophobicContact CE3-CZ 4.1Å; W363-F381 HydrophobicContact CZ3-CE2 4.39Å; W363-F381 HydrophobicContact CZ3-CZ 4.27Å
364	T	95.8	Very high	93.7	Very high	0 Å²	0	61.4 Å²	61.4	0%	0	33%	0.33	C	S	.	.	G	3₁₀ helix	trans	-48	-47.2	-174.8	-71.8	0	0	0	0	114	L305 V307 A360 I361 S366 W367 F374 Y378	L305-T364 HydrophobicContact CB-CG2 4.08Å; L305-T364 HydrophobicContact CD1-CG2 3.77Å; V307-T364 HydrophobicContact CG2-CG2 4.04Å; A360-T364 WeakPolarHBondContact O-CB 3.27Å; A360-T364 PolarHBondContact O-N 2.86Å; A360-T364 PolarHBondContact O-OG1 3.05Å; I361-T364 WeakPolarHBondContact O-CB 3.28Å; I361-T364 PolarHBondContact O-N 3.22Å; T364-S366 PolarHBondContact O-N 2.92Å; T364-S366 VanDerWaalsContact O-N 3.13Å; T364-W367 WeakPolarHBondContact O-CB 3.35Å; T364-W367 PolarHBondContact O-N 2.8Å; T364-F374 HydrophobicContact CG2-CE1 3.77Å; T364-F374 HydrophobicContact CG2-CZ 3.98Å; T364-F374 WeakPolarHBondContact O-CE1 3.38Å; T364-Y378 HydrophobicContact CG2-CE2 4.06Å; T364-Y378 WeakPolarHBondContact CG2-OH 3.48Å; T364-Y378 WeakPolarHBondContact OG1-CE2 3.33Å; T364-Y378 PolarHBondContact OG1-OH 3.15Å
365	P	93.5	Very high	93.5	Very high	70 Å²	70	63 Å²	63	46%	0.455	34%	0.34	S	S	.	.	G	3₁₀ helix	trans	-56.7	-32	-179.2	-26.2	35.8	0	0	0	114.4	L305 I361 W362 W363 W367 K368	L305-P365 HydrophobicContact CD1-CG 4.37Å; L305-P365 HydrophobicContact CD2-CG 4.06Å; I361-P365 WeakPolarHBondContact O-CD 3.37Å; W362-P365 WeakPolarHBondContact O-CD 3.43Å; W363-P365 VanDerWaalsContact C-CD 3.44Å; P365-W367 PolarHBondContact O-N 2.88Å; P365-K368 WeakPolarHBondContact O-CB 3.47Å; P365-K368 PolarHBondContact O-N 3.41Å
366	S	93.9	Very high	93.1	Very high	82 Å²	82	66 Å²	66	57%	0.573	36%	0.362	S	S	*	.	G	3₁₀ helix	trans	-74.1	-15.4	-179.4	82.6	0	0	0	0	113.5	W363 T364 K368	W363-S366 PolarHBondContact NE1-OG 3.03Å; W363-S366 PolarHBondContact O-N 3.32Å; W363-S366 PolarHBondContact O-OG 3.26Å; T364-S366 PolarHBondContact O-N 2.92Å; T364-S366 VanDerWaalsContact O-N 3.13Å; S366-K368 VanDerWaalsContact C-N 3.34Å
367	W	94.6	Very high	93	Very high	60 Å²	60	67.8 Å²	67.8	23%	0.227	37%	0.373	C	S	.	.	G	3₁₀ helix	trans	-86.5	-9.8	176.5	-71.4	75.1	0	0	0	112.4	W363 T364 P365 T369 F374 P375 Y378	W363-W367 AromaticContact CD1-CD1 3.96Å; W363-W367 AromaticContact CD1-NE1 3.75Å; W363-W367 AromaticContact CD2-NE1 3.35Å; W363-W367 AromaticContact CE2-NE1 3.29Å; W363-W367 VanDerWaalsContact CE2-NE1 3.29Å; W363-W367 AromaticContact CE3-NE1 3.88Å; W363-W367 AromaticContact CG-NE1 3.65Å; W363-W367 AromaticContact CH2-CZ2 3.91Å; W363-W367 HydrophobicContact CH2-CZ2 3.91Å; W363-W367 HydrophobicContact CZ2-CZ2 4.02Å; W363-W367 AromaticContact CZ2-NE1 3.78Å; W363-W367 HydrophobicContact CZ3-CZ2 4.2Å; W363-W367 AromaticContact NE1-NE1 3.51Å; T364-W367 WeakPolarHBondContact O-CB 3.35Å; T364-W367 PolarHBondContact O-N 2.8Å; P365-W367 PolarHBondContact O-N 2.88Å; W367-T369 PolarHBondContact O-N 2.91Å; W367-F374 HydrophobicContact CB-CD1 4.04Å; W367-F374 HydrophobicContact CB-CE1 4.41Å; W367-P375 HydrophobicContact CE3-CG 3.95Å; W367-P375 WeakPolarHBondContact O-CD 3.49Å; W367-Y378 HydrophobicContact CB-CD2 3.78Å; W367-Y378 HydrophobicContact CB-CE2 4.43Å; W367-Y378 HydrophobicContact CB-CG 4.28Å; W367-Y378 AromaticContact CD2-CD2 3.92Å; W367-Y378 HydrophobicContact CD2-CD2 3.92Å; W367-Y378 HydrophobicContact CE3-CD2 4.27Å; W367-Y378 HydrophobicContact CE3-CG 4.45Å; W367-Y378 AromaticContact CG-CD2 3.71Å; W367-Y378 HydrophobicContact CG-CD2 3.71Å; W367-Y378 HydrophobicContact CG-CE2 4.45Å; W367-Y378 HydrophobicContact CG-CG 4.49Å
368	K	92.1	Very high	92.9	Very high	85 Å²	85	67.5 Å²	67.5	37%	0.37	37%	0.372	S	S	.	.			trans	-69.9	117	-180	-165.6	170.8	-175.2	170.8	0	109.4	P365 S366 G372 F374	P365-K368 WeakPolarHBondContact O-CB 3.47Å; P365-K368 PolarHBondContact O-N 3.41Å; S366-K368 VanDerWaalsContact C-N 3.34Å; K368-G372 VanDerWaalsContact CE-O 3.32Å; K368-G372 WeakPolarHBondContact CE-O 3.27Å; K368-F374 HydrophobicContact CB-CE1 3.96Å; K368-F374 HydrophobicContact CB-CZ 4.17Å; K368-F374 HydrophobicContact CD-CZ 4.4Å; K368-F374 HydrophobicContact CG-CE1 4.48Å; K368-F374 HydrophobicContact CG-CZ 4.26Å
369	T	89.6	Confident	92.7	Very high	49 Å²	49	68.6 Å²	68.6	30%	0.301	38%	0.375	S	S	.	.			trans	-67.9	161.8	176	63.5	0	0	0	0	110.8	W367 S371 G372 R373	W367-T369 PolarHBondContact O-N 2.91Å; T369-S371 PolarHBondContact O-N 2.88Å; T369-S371 PolarHBondContact OG1-OG 3.43Å; T369-G372 WeakPolarHBondContact O-CA 3.42Å; T369-G372 PolarHBondContact O-N 3.49Å; T369-R373 WeakPolarHBondContact CB-O 3.42Å; T369-R373 WeakPolarHBondContact CG2-O 3.36Å; T369-R373 PolarHBondContact N-O 2.86Å; T369-R373 PolarHBondContact OG1-N 3.25Å; T369-R373 PolarHBondContact OG1-O 3.2Å
370	P	88.1	Confident	92.5	Very high	147 Å²	147	67.8 Å²	67.8	96%	0.955	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.1	-24.1	176.2	-26	35	0	0	0	114.1	G372	P370-G372 PolarHBondContact O-N 3.29Å
371	S	87	Confident	92.5	Very high	91 Å²	91	70.6 Å²	70.6	64%	0.636	38%	0.384	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.9	-3.7	173.8	70.7	0	0	0	0	114.1	T369 R373	T369-S371 PolarHBondContact O-N 2.88Å; T369-S371 PolarHBondContact OG1-OG 3.43Å; S371-R373 VanDerWaalsContact C-N 3.3Å
372	G	86.1	Confident	92.5	Very high	29 Å²	29	70.5 Å²	70.5	30%	0.299	38%	0.384	S	S	.	.	S	Bend	trans	82.2	1	-176.2	0	0	0	0	0	114.8	K368 T369 P370	K368-G372 VanDerWaalsContact CE-O 3.32Å; K368-G372 WeakPolarHBondContact CE-O 3.27Å; T369-G372 WeakPolarHBondContact O-CA 3.42Å; T369-G372 PolarHBondContact O-N 3.49Å; P370-G372 PolarHBondContact O-N 3.29Å
373	R	88.8	Confident	92.4	Very high	189 Å²	189	63.4 Å²	63.4	71%	0.713	36%	0.36	S	S	*	.	P	Polyproline II helix	trans	-97	160.9	179.5	-62.9	-174.6	178.6	-175.2	-0.7	112.5	T369 S371	T369-R373 WeakPolarHBondContact CB-O 3.42Å; T369-R373 WeakPolarHBondContact CG2-O 3.36Å; T369-R373 PolarHBondContact N-O 2.86Å; T369-R373 PolarHBondContact OG1-N 3.25Å; T369-R373 PolarHBondContact OG1-O 3.2Å; S371-R373 VanDerWaalsContact C-N 3.3Å
374	F	92	Very high	92.4	Very high	13 Å²	13	60.2 Å²	60.2	6%	0.057	36%	0.358	C	S	.	.	P	Polyproline II helix	trans	-99.9	140.4	173.6	-63.9	-86.5	0	0	0	111.1	V307 T364 W367 K368 Y378 Y379	V307-F374 HydrophobicContact CB-CE2 4.27Å; V307-F374 HydrophobicContact CG2-CD2 4.22Å; V307-F374 HydrophobicContact CG2-CE1 4.5Å; V307-F374 HydrophobicContact CG2-CE2 3.68Å; V307-F374 HydrophobicContact CG2-CZ 3.83Å; T364-F374 HydrophobicContact CG2-CE1 3.77Å; T364-F374 HydrophobicContact CG2-CZ 3.98Å; T364-F374 WeakPolarHBondContact O-CE1 3.38Å; W367-F374 HydrophobicContact CB-CD1 4.04Å; W367-F374 HydrophobicContact CB-CE1 4.41Å; K368-F374 HydrophobicContact CB-CE1 3.96Å; K368-F374 HydrophobicContact CB-CZ 4.17Å; K368-F374 HydrophobicContact CD-CZ 4.4Å; K368-F374 HydrophobicContact CG-CE1 4.48Å; K368-F374 HydrophobicContact CG-CZ 4.26Å; F374-Y378 HydrophobicContact CB-CD1 3.6Å; F374-Y378 HydrophobicContact CB-CE1 4.27Å; F374-Y378 HydrophobicContact CB-CG 4.13Å; F374-Y378 AromaticContact CD1-CD1 3.79Å; F374-Y378 HydrophobicContact CD1-CD1 3.79Å; F374-Y378 HydrophobicContact CD1-CD2 4.34Å; F374-Y378 AromaticContact CD1-CE1 3.9Å; F374-Y378 HydrophobicContact CD1-CE1 3.9Å; F374-Y378 HydrophobicContact CD1-CE2 4.44Å; F374-Y378 HydrophobicContact CD1-CG 4.01Å; F374-Y378 HydrophobicContact CE1-CE1 4.44Å; F374-Y378 AromaticContact CG-CD1 3.8Å; F374-Y378 HydrophobicContact CG-CD1 3.8Å; F374-Y378 HydrophobicContact CG-CE1 4.01Å; F374-Y378 HydrophobicContact CG-CG 4.38Å; F374-Y379 HydrophobicContact CB-CE2 4.06Å
375	P	92.9	Very high	92.4	Very high	36 Å²	36	60.9 Å²	60.9	23%	0.234	36%	0.362	C	S	.	.	P	Polyproline II helix	trans	-71.4	155.3	177.9	30.6	-35.3	0	0	0	111.3	W367 S377 Y378	W367-P375 HydrophobicContact CE3-CG 3.95Å; W367-P375 WeakPolarHBondContact O-CD 3.49Å; P375-S377 PolarHBondContact O-N 3.4Å; P375-S377 VanDerWaalsContact O-N 3.1Å; P375-Y378 VanDerWaalsContact O-CB 3.29Å; P375-Y378 WeakPolarHBondContact O-CB 3.42Å; P375-Y378 PolarHBondContact O-N 3.27Å
376	P	90.2	Very high	92.4	Very high	115 Å²	115	59.7 Å²	59.7	75%	0.747	35%	0.349	S	S	*	.	H	α-helix	trans	-53.7	-32.1	177.2	-28.5	36	0	0	0	114.8	Y378 Y379 G380	P376-Y378 VanDerWaalsContact C-N 3.29Å; P376-Y378 PolarHBondContact O-N 2.91Å; P376-Y379 PolarHBondContact O-N 3.26Å; P376-G380 PolarHBondContact O-N 3.4Å
377	S	93.5	Very high	92.5	Very high	72 Å²	72	56.8 Å²	56.8	50%	0.503	33%	0.329	S	S	.	.	H	α-helix	trans	-62.8	-32.2	176.2	48.8	0	0	0	0	113.3	P375 G380 F381	P375-S377 PolarHBondContact O-N 3.4Å; P375-S377 VanDerWaalsContact O-N 3.1Å; S377-G380 PolarHBondContact O-N 3.25Å; S377-F381 PolarHBondContact O-N 3.04Å
378	Y	94.8	Very high	92.6	Very high	0 Å²	0	58.5 Å²	58.5	0%	0	34%	0.342	C	S	.	.	H	α-helix	trans	-63.9	-47.2	173.6	170.8	-102.2	0	0	0	111.1	L302 V307 T364 W367 F374 P375 P376 G380 F381 I382	L302-Y378 VanDerWaalsContact CD2-OH 3.25Å; L302-Y378 WeakPolarHBondContact CD2-OH 3.39Å; V307-Y378 HydrophobicContact CG1-CE1 4.3Å; V307-Y378 HydrophobicContact CG2-CE1 4.14Å; T364-Y378 HydrophobicContact CG2-CE2 4.06Å; T364-Y378 WeakPolarHBondContact CG2-OH 3.48Å; T364-Y378 WeakPolarHBondContact OG1-CE2 3.33Å; T364-Y378 PolarHBondContact OG1-OH 3.15Å; W367-Y378 HydrophobicContact CB-CD2 3.78Å; W367-Y378 HydrophobicContact CB-CE2 4.43Å; W367-Y378 HydrophobicContact CB-CG 4.28Å; W367-Y378 AromaticContact CD2-CD2 3.92Å; W367-Y378 HydrophobicContact CD2-CD2 3.92Å; W367-Y378 HydrophobicContact CE3-CD2 4.27Å; W367-Y378 HydrophobicContact CE3-CG 4.45Å; W367-Y378 AromaticContact CG-CD2 3.71Å; W367-Y378 HydrophobicContact CG-CD2 3.71Å; W367-Y378 HydrophobicContact CG-CE2 4.45Å; W367-Y378 HydrophobicContact CG-CG 4.49Å; F374-Y378 HydrophobicContact CB-CD1 3.6Å; F374-Y378 HydrophobicContact CB-CE1 4.27Å; F374-Y378 HydrophobicContact CB-CG 4.13Å; F374-Y378 AromaticContact CD1-CD1 3.79Å; F374-Y378 HydrophobicContact CD1-CD1 3.79Å; F374-Y378 HydrophobicContact CD1-CD2 4.34Å; F374-Y378 AromaticContact CD1-CE1 3.9Å; F374-Y378 HydrophobicContact CD1-CE1 3.9Å; F374-Y378 HydrophobicContact CD1-CE2 4.44Å; F374-Y378 HydrophobicContact CD1-CG 4.01Å; F374-Y378 HydrophobicContact CE1-CE1 4.44Å; F374-Y378 AromaticContact CG-CD1 3.8Å; F374-Y378 HydrophobicContact CG-CD1 3.8Å; F374-Y378 HydrophobicContact CG-CE1 4.01Å; F374-Y378 HydrophobicContact CG-CG 4.38Å; P375-Y378 VanDerWaalsContact O-CB 3.29Å; P375-Y378 WeakPolarHBondContact O-CB 3.42Å; P375-Y378 PolarHBondContact O-N 3.27Å; P376-Y378 VanDerWaalsContact C-N 3.29Å; P376-Y378 PolarHBondContact O-N 2.91Å; Y378-G380 VanDerWaalsContact C-N 3.29Å; Y378-G380 PolarHBondContact O-N 2.83Å; Y378-F381 WeakPolarHBondContact O-CB 3.4Å; Y378-F381 PolarHBondContact O-N 3.46Å; Y378-F381 VanDerWaalsContact O-N 3.11Å; Y378-I382 HydrophobicContact CD1-CG1 4.33Å; Y378-I382 HydrophobicContact CD2-CG1 4.25Å; Y378-I382 HydrophobicContact CE1-CG1 3.85Å; Y378-I382 HydrophobicContact CE2-CD1 3.93Å; Y378-I382 HydrophobicContact CE2-CG1 3.75Å; Y378-I382 WeakPolarHBondContact O-CG1 3.37Å; Y378-I382 PolarHBondContact O-N 2.96Å
379	Y	93	Very high	92.7	Very high	29 Å²	29	55 Å²	55	11%	0.114	33%	0.327	C	S	.	.	H	α-helix	trans	-63.3	-37.2	177.2	-63.8	-66.1	0	0	0	111.8	V307 P308 E311 F374 P376 I382 L383	V307-Y379 HydrophobicContact CG1-CE1 3.98Å; P308-Y379 WeakPolarHBondContact CD-OH 3.22Å; E311-Y379 HydrophobicContact CB-CD1 4.34Å; E311-Y379 HydrophobicContact CB-CE1 3.6Å; E311-Y379 HydrophobicContact CG-CE1 4.33Å; F374-Y379 HydrophobicContact CB-CE2 4.06Å; P376-Y379 PolarHBondContact O-N 3.26Å; Y379-I382 PolarHBondContact O-N 2.82Å; Y379-L383 WeakPolarHBondContact O-CB 3.48Å; Y379-L383 PolarHBondContact O-N 2.88Å
380	G	94	Very high	92.9	Very high	40 Å²	40	54.4 Å²	54.4	41%	0.412	32%	0.321	S	S	.	.	H	α-helix	trans	-61.3	-41.2	171.3	0	0	0	0	0	113.2	P376 S377 Y378 A384	P376-G380 PolarHBondContact O-N 3.4Å; S377-G380 PolarHBondContact O-N 3.25Å; Y378-G380 VanDerWaalsContact C-N 3.29Å; Y378-G380 PolarHBondContact O-N 2.83Å; G380-A384 PolarHBondContact O-N 2.96Å
381	F	95.5	Very high	93.3	Very high	62 Å²	62	50.5 Å²	50.5	27%	0.272	29%	0.291	S	S	.	.	H	α-helix	trans	-63.8	-49.4	175	167.8	-104.5	0	0	0	112.2	A360 W363 S377 Y378 L383 A384 I385	A360-F381 HydrophobicContact CB-CE1 3.78Å; A360-F381 HydrophobicContact CB-CZ 4.15Å; W363-F381 HydrophobicContact CE3-CE1 4.44Å; W363-F381 HydrophobicContact CE3-CZ 4.1Å; W363-F381 HydrophobicContact CZ3-CE2 4.39Å; W363-F381 HydrophobicContact CZ3-CZ 4.27Å; S377-F381 PolarHBondContact O-N 3.04Å; Y378-F381 WeakPolarHBondContact O-CB 3.4Å; Y378-F381 PolarHBondContact O-N 3.46Å; Y378-F381 VanDerWaalsContact O-N 3.11Å; F381-L383 PolarHBondContact O-N 3.47Å; F381-A384 WeakPolarHBondContact O-CB 3.46Å; F381-A384 PolarHBondContact O-N 3.47Å; F381-I385 HydrophobicContact CD1-CD1 4.45Å; F381-I385 HydrophobicContact CE1-CD1 3.8Å; F381-I385 HydrophobicContact CE2-CD1 3.88Å; F381-I385 HydrophobicContact CE2-CG1 4.5Å; F381-I385 HydrophobicContact CZ-CD1 3.49Å; F381-I385 VanDerWaalsContact CZ-CD1 3.49Å; F381-I385 PolarHBondContact O-N 2.71Å
382	I	95	Very high	93.8	Very high	4 Å²	4	46.8 Å²	46.8	2%	0.021	27%	0.265	C	S	.	.	H	α-helix	trans	-61.3	-45.6	177.2	-65.2	-61.7	0	0	0	110.4	L302 L315 A360 Y378 Y379 A384 I385 F386	L302-I382 HydrophobicContact CD2-CD1 4.44Å; L315-I382 HydrophobicContact CD1-CB 4.33Å; L315-I382 HydrophobicContact CD1-CG2 3.67Å; A360-I382 HydrophobicContact CB-CD1 4.15Å; Y378-I382 HydrophobicContact CD1-CG1 4.33Å; Y378-I382 HydrophobicContact CD2-CG1 4.25Å; Y378-I382 HydrophobicContact CE1-CG1 3.85Å; Y378-I382 HydrophobicContact CE2-CD1 3.93Å; Y378-I382 HydrophobicContact CE2-CG1 3.75Å; Y378-I382 WeakPolarHBondContact O-CG1 3.37Å; Y378-I382 PolarHBondContact O-N 2.96Å; Y379-I382 PolarHBondContact O-N 2.82Å; I382-A384 VanDerWaalsContact C-N 3.27Å; I382-A384 PolarHBondContact O-N 2.88Å; I382-I385 PolarHBondContact O-N 3.37Å; I382-I385 VanDerWaalsContact O-N 3.13Å; I382-F386 HydrophobicContact CG2-CD2 3.48Å; I382-F386 VanDerWaalsContact CG2-CD2 3.48Å; I382-F386 HydrophobicContact CG2-CE2 3.5Å; I382-F386 VanDerWaalsContact CG2-CE2 3.5Å; I382-F386 WeakPolarHBondContact O-CD2 3.36Å; I382-F386 PolarHBondContact O-N 2.66Å
383	L	94.7	Very high	94.2	Very high	41 Å²	41	47 Å²	47	22%	0.215	26%	0.261	C	S	.	.	H	α-helix	trans	-56.2	-40.7	176.1	179.1	58.8	0	0	0	112.3	L315 P318 I319 Y379 F381 F386 S387	L315-L383 HydrophobicContact CB-CD1 4.43Å; L315-L383 HydrophobicContact CD2-CB 4.22Å; P318-L383 HydrophobicContact CB-CD1 4.49Å; P318-L383 HydrophobicContact CB-CD2 4.26Å; P318-L383 HydrophobicContact CG-CD1 3.72Å; P318-L383 HydrophobicContact CG-CD2 3.77Å; P318-L383 HydrophobicContact CG-CG 4.42Å; I319-L383 HydrophobicContact CD1-CD1 4.16Å; I319-L383 HydrophobicContact CG1-CD1 3.84Å; Y379-L383 WeakPolarHBondContact O-CB 3.48Å; Y379-L383 PolarHBondContact O-N 2.88Å; F381-L383 PolarHBondContact O-N 3.47Å; L383-F386 PolarHBondContact O-N 2.93Å; L383-S387 VanDerWaalsContact O-CB 3.25Å; L383-S387 WeakPolarHBondContact O-CB 3.5Å; L383-S387 PolarHBondContact O-N 3.42Å; L383-S387 PolarHBondContact O-OG 3.47Å
384	A	95.6	Very high	94.4	Very high	50 Å²	50	39.5 Å²	39.5	41%	0.413	23%	0.233	S	C	.	.	H	α-helix	trans	-62.4	-43.5	177.7	0	0	0	0	0	111.8	G380 F381 I382 S387 L388	G380-A384 PolarHBondContact O-N 2.96Å; F381-A384 WeakPolarHBondContact O-CB 3.46Å; F381-A384 PolarHBondContact O-N 3.47Å; I382-A384 VanDerWaalsContact C-N 3.27Å; I382-A384 PolarHBondContact O-N 2.88Å; A384-S387 PolarHBondContact O-N 2.72Å; A384-L388 WeakPolarHBondContact O-CG 3.39Å; A384-L388 PolarHBondContact O-N 3.12Å
385	I	95.7	Very high	94.6	Very high	15 Å²	15	39.7 Å²	39.7	8%	0.077	24%	0.236	C	C	.	.	H	α-helix	trans	-65.9	-46.6	177.8	-59.4	177.7	0	0	0	110.7	A356 F357 A360 F381 I382 S387 L388 Q389	A356-I385 HydrophobicContact CB-CG2 4.28Å; F357-I385 HydrophobicContact CD1-CG2 3.79Å; F357-I385 HydrophobicContact CD2-CG2 4.44Å; F357-I385 HydrophobicContact CE1-CB 4.25Å; F357-I385 HydrophobicContact CE1-CG2 3.43Å; F357-I385 VanDerWaalsContact CE1-CG2 3.43Å; F357-I385 HydrophobicContact CE2-CG2 4.12Å; F357-I385 HydrophobicContact CG-CG2 4.27Å; F357-I385 HydrophobicContact CZ-CG2 3.6Å; A360-I385 HydrophobicContact CB-CD1 3.68Å; F381-I385 HydrophobicContact CD1-CD1 4.45Å; F381-I385 HydrophobicContact CE1-CD1 3.8Å; F381-I385 HydrophobicContact CE2-CD1 3.88Å; F381-I385 HydrophobicContact CE2-CG1 4.5Å; F381-I385 HydrophobicContact CZ-CD1 3.49Å; F381-I385 VanDerWaalsContact CZ-CD1 3.49Å; F381-I385 PolarHBondContact O-N 2.71Å; I382-I385 PolarHBondContact O-N 3.37Å; I382-I385 VanDerWaalsContact O-N 3.13Å; I385-S387 VanDerWaalsContact C-N 3.3Å; I385-S387 PolarHBondContact O-N 3.11Å; I385-L388 PolarHBondContact O-N 3.35Å; I385-Q389 PolarHBondContact O-N 3.19Å
386	F	94.5	Very high	94.8	Very high	45 Å²	45	38.4 Å²	38.4	20%	0.197	23%	0.227	C	C	.	.	H	α-helix	trans	-61.3	-38.4	175.7	-85.9	-81	0	0	0	112.1	L302 I319 F357 I382 L383 Q389 Q390	L302-F386 HydrophobicContact CD1-CE2 4.09Å; L302-F386 HydrophobicContact CD1-CZ 4.3Å; I319-F386 HydrophobicContact CD1-CB 3.94Å; F357-F386 HydrophobicContact CE1-CD1 4.26Å; F357-F386 AromaticContact CE1-CD2 3.93Å; F357-F386 HydrophobicContact CE1-CD2 3.93Å; F357-F386 HydrophobicContact CE1-CE1 4.13Å; F357-F386 AromaticContact CE1-CE2 3.8Å; F357-F386 HydrophobicContact CE1-CE2 3.8Å; F357-F386 HydrophobicContact CE1-CG 4.17Å; F357-F386 AromaticContact CE1-CZ 3.9Å; F357-F386 HydrophobicContact CE1-CZ 3.9Å; F357-F386 HydrophobicContact CZ-CD1 4.13Å; F357-F386 HydrophobicContact CZ-CD2 4.48Å; F357-F386 HydrophobicContact CZ-CE1 4.24Å; F357-F386 HydrophobicContact CZ-CG 4.26Å; F357-F386 HydrophobicContact CZ-CZ 4.46Å; I382-F386 HydrophobicContact CG2-CD2 3.48Å; I382-F386 VanDerWaalsContact CG2-CD2 3.48Å; I382-F386 HydrophobicContact CG2-CE2 3.5Å; I382-F386 VanDerWaalsContact CG2-CE2 3.5Å; I382-F386 WeakPolarHBondContact O-CD2 3.36Å; I382-F386 PolarHBondContact O-N 2.66Å; L383-F386 PolarHBondContact O-N 2.93Å; F386-Q389 WeakPolarHBondContact O-CB 3.46Å; F386-Q389 PolarHBondContact O-N 3.32Å; F386-Q390 VanDerWaalsContact O-CG 3.32Å; F386-Q390 WeakPolarHBondContact O-CG 3.13Å; F386-Q390 PolarHBondContact O-N 2.83Å
387	S	95.1	Very high	95	Very high	21 Å²	21	35.7 Å²	35.7	15%	0.147	20%	0.204	C	C	.	.	H	α-helix	trans	-63.4	-43.7	176.6	-61.1	0	0	0	0	111.7	L383 A384 I385 Q390 I391	L383-S387 VanDerWaalsContact O-CB 3.25Å; L383-S387 WeakPolarHBondContact O-CB 3.5Å; L383-S387 PolarHBondContact O-N 3.42Å; L383-S387 PolarHBondContact O-OG 3.47Å; A384-S387 PolarHBondContact O-N 2.72Å; I385-S387 VanDerWaalsContact C-N 3.3Å; I385-S387 PolarHBondContact O-N 3.11Å; S387-Q390 PolarHBondContact O-N 3.23Å; S387-I391 WeakPolarHBondContact O-CG1 3.47Å; S387-I391 PolarHBondContact O-N 3.38Å
388	L	96	Very high	95.1	Very high	96 Å²	96	32.3 Å²	32.3	50%	0.503	18%	0.18	S	C	.	.	H	α-helix	trans	-63.5	-41.4	174.4	-69.5	171.9	0	0	0	111.9	L353 A384 I385 Q390 I391 T392	L353-L388 HydrophobicContact CD1-CB 4.07Å; L353-L388 WeakPolarHBondContact CD1-O 3.3Å; L353-L388 HydrophobicContact CD2-CB 3.87Å; L353-L388 HydrophobicContact CD2-CD1 4.34Å; A384-L388 WeakPolarHBondContact O-CG 3.39Å; A384-L388 PolarHBondContact O-N 3.12Å; I385-L388 PolarHBondContact O-N 3.35Å; L388-Q390 VanDerWaalsContact C-N 3.34Å; L388-Q390 PolarHBondContact O-N 3.35Å; L388-I391 PolarHBondContact O-N 3.42Å; L388-T392 PolarHBondContact O-N 2.92Å; L388-T392 PolarHBondContact O-OG1 3.25Å
389	Q	95.5	Very high	95.2	Very high	12 Å²	12	32.3 Å²	32.3	6%	0.056	18%	0.18	C	C	.	.	H	α-helix	trans	-58.1	-46.9	172.8	178.6	-169.9	20.4	0	0	110.4	D295 R350 F357 I385 F386 I391 T392 S393	D295-Q389 PolarHBondContact OD1-NE2 3.49Å; R350-Q389 VanDerWaalsContact CZ-CG 3.41Å; R350-Q389 PolarHBondContact NH1-O 2.98Å; R350-Q389 VanDerWaalsContact NH2-NE2 3.17Å; F357-Q389 HydrophobicContact CE2-CB 3.82Å; F357-Q389 HydrophobicContact CE2-CG 3.86Å; F357-Q389 HydrophobicContact CZ-CB 3.84Å; F357-Q389 HydrophobicContact CZ-CG 4.17Å; I385-Q389 PolarHBondContact O-N 3.19Å; F386-Q389 WeakPolarHBondContact O-CB 3.46Å; F386-Q389 PolarHBondContact O-N 3.32Å; Q389-I391 PolarHBondContact O-N 2.98Å; Q389-T392 PolarHBondContact O-N 3.44Å; Q389-T392 PolarHBondContact O-OG1 3.26Å; Q389-S393 WeakPolarHBondContact O-CB 3.31Å; Q389-S393 PolarHBondContact O-N 2.99Å
390	Q	93.9	Very high	95.3	Very high	36 Å²	36	31.1 Å²	31.1	17%	0.168	18%	0.175	C	C	.	.	H	α-helix	trans	-65.6	-37.2	-179	-69.9	-59.6	78.4	0	0	113	I319 E323 F386 S387 L388 T392 S393 Y394	I319-Q390 HydrophobicContact CG2-CB 4.22Å; I319-Q390 HydrophobicContact CG2-CG 3.73Å; E323-Q390 PolarHBondContact OE1-NE2 3.38Å; F386-Q390 VanDerWaalsContact O-CG 3.32Å; F386-Q390 WeakPolarHBondContact O-CG 3.13Å; F386-Q390 PolarHBondContact O-N 2.83Å; S387-Q390 PolarHBondContact O-N 3.23Å; L388-Q390 VanDerWaalsContact C-N 3.34Å; L388-Q390 PolarHBondContact O-N 3.35Å; Q390-T392 VanDerWaalsContact C-N 3.32Å; Q390-T392 PolarHBondContact O-N 2.86Å; Q390-S393 WeakPolarHBondContact O-CB 3.27Å; Q390-S393 PolarHBondContact O-N 2.85Å; Q390-Y394 WeakPolarHBondContact O-CB 3.49Å; Q390-Y394 WeakPolarHBondContact O-CD2 3.41Å; Q390-Y394 PolarHBondContact O-N 3.4Å
391	I	95.8	Very high	95.3	Very high	64 Å²	64	29.6 Å²	29.6	33%	0.328	16%	0.158	S	C	.	.	H	α-helix	trans	-57.4	-47.6	174.2	-68.2	164.3	0	0	0	111.1	I322 L326 S387 L388 Q389 C395	I322-I391 HydrophobicContact CG2-CG1 4Å; L326-I391 HydrophobicContact CD1-CG2 4.37Å; L326-I391 HydrophobicContact CD2-CB 4.19Å; L326-I391 HydrophobicContact CD2-CG1 4.25Å; L326-I391 HydrophobicContact CD2-CG2 4.14Å; S387-I391 WeakPolarHBondContact O-CG1 3.47Å; S387-I391 PolarHBondContact O-N 3.38Å; L388-I391 PolarHBondContact O-N 3.42Å; Q389-I391 PolarHBondContact O-N 2.98Å; I391-C395 PolarHBondContact O-N 3.27Å; I391-C395 VanDerWaalsContact O-N 3.1Å; I391-C395 PolarHBondContact O-SG 3.05Å
392	T	96.4	Very high	95.3	Very high	14 Å²	14	26.7 Å²	26.7	9%	0.086	15%	0.145	C	C	.	.	H	α-helix	trans	-70.9	-35.3	179.5	58.4	0	0	0	0	112.3	R350 L353 L388 Q389 Q390 C395 I396	R350-T392 WeakPolarHBondContact CD-OG1 3.04Å; L353-T392 HydrophobicContact CD1-CG2 4.02Å; L388-T392 PolarHBondContact O-N 2.92Å; L388-T392 PolarHBondContact O-OG1 3.25Å; Q389-T392 PolarHBondContact O-N 3.44Å; Q389-T392 PolarHBondContact O-OG1 3.26Å; Q390-T392 VanDerWaalsContact C-N 3.32Å; Q390-T392 PolarHBondContact O-N 2.86Å; T392-C395 PolarHBondContact O-N 3.45Å; T392-I396 PolarHBondContact O-N 3.29Å; T392-I396 VanDerWaalsContact O-N 3.12Å
393	S	94.8	Very high	95.4	Very high	32 Å²	32	26.8 Å²	26.8	22%	0.224	15%	0.145	C	C	.	.	H	α-helix	trans	-57	-51.9	174.3	-143.5	0	0	0	0	111.7	R350 Q389 Q390 I396 F397	R350-S393 PolarHBondContact NH1-OG 3.13Å; R350-S393 VanDerWaalsContact NH1-OG 3.07Å; Q389-S393 WeakPolarHBondContact O-CB 3.31Å; Q389-S393 PolarHBondContact O-N 2.99Å; Q390-S393 WeakPolarHBondContact O-CB 3.27Å; Q390-S393 PolarHBondContact O-N 2.85Å; S393-I396 WeakPolarHBondContact O-CB 3.3Å; S393-I396 PolarHBondContact O-N 3.37Å; S393-F397 WeakPolarHBondContact O-CB 3.44Å; S393-F397 PolarHBondContact O-N 3.32Å
394	Y	94.4	Very high	95.4	Very high	32 Å²	32	24.8 Å²	24.8	13%	0.125	14%	0.135	C	C	.	.	H	α-helix	trans	-73.2	-32.4	-175	-87.9	-107.2	0	0	0	111.5	V179 E323 P327 Q390 I396 F397 V398	V179-Y394 HydrophobicContact CG1-CD1 3.68Å; V179-Y394 HydrophobicContact CG1-CE1 3.44Å; V179-Y394 VanDerWaalsContact CG1-CE1 3.44Å; E323-Y394 HydrophobicContact CB-CD1 4.45Å; E323-Y394 HydrophobicContact CB-CE1 3.68Å; E323-Y394 HydrophobicContact CB-CE2 4.09Å; E323-Y394 VanDerWaalsContact CB-CZ 3.5Å; E323-Y394 HydrophobicContact CG-CD2 4.27Å; E323-Y394 HydrophobicContact CG-CE1 4.09Å; E323-Y394 HydrophobicContact CG-CE2 3.52Å; E323-Y394 VanDerWaalsContact CG-CZ 3.43Å; E323-Y394 WeakPolarHBondContact CG-OH 3.49Å; E323-Y394 PolarHBondContact OE2-OH 3.2Å; P327-Y394 HydrophobicContact CG-CD1 4.14Å; Q390-Y394 WeakPolarHBondContact O-CB 3.49Å; Q390-Y394 WeakPolarHBondContact O-CD2 3.41Å; Q390-Y394 PolarHBondContact O-N 3.4Å; Y394-I396 VanDerWaalsContact C-N 3.32Å; Y394-I396 PolarHBondContact O-N 3.22Å; Y394-F397 PolarHBondContact O-N 3.46Å; Y394-V398 VanDerWaalsContact O-CB 3.32Å; Y394-V398 WeakPolarHBondContact O-CB 3.46Å; Y394-V398 VanDerWaalsContact O-CG2 3.24Å; Y394-V398 WeakPolarHBondContact O-CG2 3.34Å; Y394-V398 PolarHBondContact O-N 3.43Å
395	C	95.9	Very high	95.3	Very high	17 Å²	17	22.7 Å²	22.7	12%	0.115	12%	0.117	C	C	.	.	H	α-helix	trans	-56.9	-46.7	168.2	-71.9	0	0	0	0	111.7	V342 A346 I391 T392 S399	V342-C395 HydrophobicContact CG1-CB 4.08Å; A346-C395 HydrophobicContact CB-CB 3.58Å; I391-C395 PolarHBondContact O-N 3.27Å; I391-C395 VanDerWaalsContact O-N 3.1Å; I391-C395 PolarHBondContact O-SG 3.05Å; T392-C395 PolarHBondContact O-N 3.45Å; C395-S399 VanDerWaalsContact O-CB 3.25Å; C395-S399 WeakPolarHBondContact O-CB 3.33Å; C395-S399 PolarHBondContact O-N 2.98Å; C395-S399 PolarHBondContact O-OG 3.21Å
396	I	95.9	Very high	95.2	Very high	9 Å²	9	22.8 Å²	22.8	5%	0.046	12%	0.118	C	C	.	.	H	α-helix	trans	-63.9	-47.9	176.3	-78.9	168.6	0	0	0	110.9	F291 Y343 A346 Y347 R350 T392 S393 Y394 S399 Q400	F291-I396 HydrophobicContact CE2-CD1 4.32Å; Y343-I396 HydrophobicContact CD1-CG1 4.28Å; Y343-I396 HydrophobicContact CD2-CB 4.19Å; Y343-I396 HydrophobicContact CD2-CG1 4.22Å; Y343-I396 HydrophobicContact CD2-CG2 3.79Å; Y343-I396 HydrophobicContact CE1-CG1 4.4Å; Y343-I396 HydrophobicContact CE2-CB 4.26Å; Y343-I396 HydrophobicContact CE2-CG1 4.37Å; Y343-I396 HydrophobicContact CE2-CG2 3.41Å; Y343-I396 VanDerWaalsContact CE2-CG2 3.41Å; Y343-I396 HydrophobicContact CG-CG1 4.17Å; A346-I396 HydrophobicContact CB-CG1 4.2Å; Y347-I396 HydrophobicContact CD2-CD1 4.34Å; R350-I396 HydrophobicContact CB-CD1 4.13Å; R350-I396 HydrophobicContact CG-CD1 4.2Å; T392-I396 PolarHBondContact O-N 3.29Å; T392-I396 VanDerWaalsContact O-N 3.12Å; S393-I396 WeakPolarHBondContact O-CB 3.3Å; S393-I396 PolarHBondContact O-N 3.37Å; Y394-I396 VanDerWaalsContact C-N 3.32Å; Y394-I396 PolarHBondContact O-N 3.22Å; I396-S399 PolarHBondContact O-OG 2.82Å; I396-Q400 VanDerWaalsContact O-CB 3.28Å; I396-Q400 WeakPolarHBondContact O-CB 3.33Å; I396-Q400 PolarHBondContact O-N 3.45Å
397	F	95	Very high	95.1	Very high	59 Å²	59	21 Å²	21	26%	0.259	11%	0.11	S	C	.	.	H	α-helix	trans	-66.6	-49.4	-175.7	-177.4	-118.6	0	0	0	112.9	V179 S393 Y394 S399 Q400 M401	V179-F397 HydrophobicContact CG2-CD1 3.67Å; V179-F397 HydrophobicContact CG2-CE1 3.45Å; V179-F397 VanDerWaalsContact CG2-CE1 3.45Å; S393-F397 WeakPolarHBondContact O-CB 3.44Å; S393-F397 PolarHBondContact O-N 3.32Å; Y394-F397 PolarHBondContact O-N 3.46Å; F397-S399 PolarHBondContact O-N 2.78Å; F397-Q400 PolarHBondContact O-N 3.01Å; F397-M401 HydrophobicContact CD2-CG 4.34Å; F397-M401 HydrophobicContact CE1-CG 4.48Å; F397-M401 HydrophobicContact CE2-CG 4.01Å; F397-M401 HydrophobicContact CE2-SD 4.43Å; F397-M401 HydrophobicContact CZ-CG 4.09Å; F397-M401 WeakPolarHBondContact O-CB 3.49Å; F397-M401 WeakPolarHBondContact O-CG 3.35Å; F397-M401 PolarHBondContact O-N 3.36Å
398	V	95.4	Very high	95	Very high	0 Å²	0	20.2 Å²	20.2	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-65.8	-38.7	-179	176.4	0	0	0	0	111.4	S175 V179 P327 I330 T334 Y394 A402	S175-V398 WeakPolarHBondContact CB-O 3.19Å; S175-V398 PolarHBondContact OG-O 3.12Å; V179-V398 HydrophobicContact CB-CG2 4.27Å; V179-V398 HydrophobicContact CG1-CG2 4.33Å; V179-V398 HydrophobicContact CG2-CG2 3.8Å; P327-V398 HydrophobicContact CB-CG2 4.09Å; P327-V398 HydrophobicContact CG-CG2 4.1Å; I330-V398 HydrophobicContact CD1-CB 3.89Å; I330-V398 HydrophobicContact CD1-CG1 4.15Å; I330-V398 HydrophobicContact CD1-CG2 4.14Å; I330-V398 HydrophobicContact CG1-CG1 4.4Å; T334-V398 HydrophobicContact CG2-CG1 4.16Å; Y394-V398 VanDerWaalsContact O-CB 3.32Å; Y394-V398 WeakPolarHBondContact O-CB 3.46Å; Y394-V398 VanDerWaalsContact O-CG2 3.24Å; Y394-V398 WeakPolarHBondContact O-CG2 3.34Å; Y394-V398 PolarHBondContact O-N 3.43Å; V398-A402 VanDerWaalsContact O-CB 3.28Å; V398-A402 WeakPolarHBondContact O-CB 3.42Å; V398-A402 PolarHBondContact O-N 3.07Å
399	S	96.3	Very high	94.5	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-66.8	-41	176.5	56	0	0	0	0	112.5	P339 Y343 C395 I396 F397 A402 F403	P339-S399 WeakPolarHBondContact O-CB 3.3Å; Y343-S399 WeakPolarHBondContact CB-OG 3.34Å; Y343-S399 PolarHBondContact N-OG 3.48Å; C395-S399 VanDerWaalsContact O-CB 3.25Å; C395-S399 WeakPolarHBondContact O-CB 3.33Å; C395-S399 PolarHBondContact O-N 2.98Å; C395-S399 PolarHBondContact O-OG 3.21Å; I396-S399 PolarHBondContact O-OG 2.82Å; F397-S399 PolarHBondContact O-N 2.78Å; S399-A402 PolarHBondContact O-N 3.24Å; S399-F403 PolarHBondContact O-N 2.99Å
400	Q	95.9	Very high	93.9	Very high	4 Å²	4	17.1 Å²	17.1	2%	0.019	9%	0.09	C	C	.	.	H	α-helix	trans	-61.1	-49.9	174.8	-170.8	-163.9	-83.7	0	0	111.2	Y284 Y343 I396 F397 A402 F403 H404	Y284-Q400 HydrophobicContact CE1-CG 3.77Å; Y284-Q400 HydrophobicContact CE2-CG 4.32Å; Y284-Q400 WeakPolarHBondContact OH-CG 3.34Å; Y343-Q400 HydrophobicContact CD2-CB 4.48Å; I396-Q400 VanDerWaalsContact O-CB 3.28Å; I396-Q400 WeakPolarHBondContact O-CB 3.33Å; I396-Q400 PolarHBondContact O-N 3.45Å; F397-Q400 PolarHBondContact O-N 3.01Å; Q400-A402 VanDerWaalsContact C-N 3.33Å; Q400-A402 PolarHBondContact O-N 3.47Å; Q400-F403 WeakPolarHBondContact O-CB 3.4Å; Q400-F403 PolarHBondContact O-N 2.84Å; Q400-F403 VanDerWaalsContact O-N 3.16Å; Q400-H404 PolarHBondContact O-CD2 3.18Å; Q400-H404 VanDerWaalsContact O-CG 3.31Å; Q400-H404 PolarHBondContact O-N 3.36Å
401	M	95	Very high	93.4	Very high	9 Å²	9	16.5 Å²	16.5	4%	0.044	9%	0.089	C	C	.	.	H	α-helix	trans	-62.7	-38.1	177.9	-72.7	-65.7	-67.6	0	0	112.3	F397 F403 H404 A405 M417 N421	F397-M401 HydrophobicContact CD2-CG 4.34Å; F397-M401 HydrophobicContact CE1-CG 4.48Å; F397-M401 HydrophobicContact CE2-CG 4.01Å; F397-M401 HydrophobicContact CE2-SD 4.43Å; F397-M401 HydrophobicContact CZ-CG 4.09Å; F397-M401 WeakPolarHBondContact O-CB 3.49Å; F397-M401 WeakPolarHBondContact O-CG 3.35Å; F397-M401 PolarHBondContact O-N 3.36Å; M401-F403 VanDerWaalsContact C-N 3.31Å; M401-F403 PolarHBondContact O-N 3.14Å; M401-H404 PolarHBondContact O-N 2.83Å; M401-A405 PolarHBondContact O-N 3.03Å; M401-M417 HydrophobicContact CE-CE 4.32Å; M401-N421 PolarHBondContact SD-OD1 2.87Å
402	A	95.4	Very high	92.9	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-62.7	-41.7	175.2	0	0	0	0	0	110.8	S175 P339 V398 S399 Q400 A405 Q406	S175-A402 VanDerWaalsContact CB-N 3.35Å; S175-A402 WeakPolarHBondContact OG-CB 3.24Å; P339-A402 HydrophobicContact CB-CB 3.89Å; V398-A402 VanDerWaalsContact O-CB 3.28Å; V398-A402 WeakPolarHBondContact O-CB 3.42Å; V398-A402 PolarHBondContact O-N 3.07Å; S399-A402 PolarHBondContact O-N 3.24Å; Q400-A402 VanDerWaalsContact C-N 3.33Å; Q400-A402 PolarHBondContact O-N 3.47Å; A402-A405 PolarHBondContact O-N 2.94Å; A402-Q406 VanDerWaalsContact O-CG 3.29Å; A402-Q406 WeakPolarHBondContact O-CG 3.47Å; A402-Q406 PolarHBondContact O-N 3.48Å; A402-Q406 VanDerWaalsContact O-N 3.08Å
403	F	96.1	Very high	92.4	Very high	6 Å²	6	12.8 Å²	12.8	3%	0.026	7%	0.069	C	C	.	.	H	α-helix	trans	-63.2	-45.3	175.4	-173	-110.9	0	0	0	111.8	L280 P339 L340 S399 Q400 M401 A405 Q406 V407 L487 Q488 W495	L280-F403 HydrophobicContact CD1-CD1 4.26Å; L280-F403 HydrophobicContact CD1-CE1 3.83Å; L280-F403 HydrophobicContact CD2-CD1 4.29Å; L280-F403 HydrophobicContact CD2-CE1 3.92Å; P339-F403 HydrophobicContact CB-CB 4.39Å; P339-F403 HydrophobicContact CG-CB 3.7Å; P339-F403 HydrophobicContact CG-CD2 3.78Å; P339-F403 HydrophobicContact CG-CG 4.23Å; L340-F403 HydrophobicContact CD1-CB 4.34Å; L340-F403 HydrophobicContact CD1-CD1 3.78Å; L340-F403 HydrophobicContact CD1-CD2 3.88Å; L340-F403 HydrophobicContact CD1-CE1 3.97Å; L340-F403 HydrophobicContact CD1-CE2 4.07Å; L340-F403 HydrophobicContact CD1-CG 3.72Å; L340-F403 HydrophobicContact CD1-CZ 4.1Å; L340-F403 HydrophobicContact CD2-CB 3.71Å; L340-F403 HydrophobicContact CD2-CD1 4.37Å; L340-F403 HydrophobicContact CD2-CG 4.02Å; L340-F403 HydrophobicContact CG-CB 3.96Å; L340-F403 HydrophobicContact CG-CD1 4.34Å; L340-F403 HydrophobicContact CG-CD2 4.04Å; L340-F403 HydrophobicContact CG-CG 3.85Å; S399-F403 PolarHBondContact O-N 2.99Å; Q400-F403 WeakPolarHBondContact O-CB 3.4Å; Q400-F403 PolarHBondContact O-N 2.84Å; Q400-F403 VanDerWaalsContact O-N 3.16Å; M401-F403 VanDerWaalsContact C-N 3.31Å; M401-F403 PolarHBondContact O-N 3.14Å; F403-A405 VanDerWaalsContact C-N 3.3Å; F403-A405 PolarHBondContact O-N 3.4Å; F403-Q406 PolarHBondContact O-N 3Å; F403-V407 HydrophobicContact CD1-CG1 4.41Å; F403-V407 HydrophobicContact CD2-CG1 4.17Å; F403-V407 HydrophobicContact CE1-CG1 3.97Å; F403-V407 HydrophobicContact CE1-CG2 4.42Å; F403-V407 HydrophobicContact CE2-CG1 3.7Å; F403-V407 HydrophobicContact CZ-CG1 3.61Å; F403-V407 WeakPolarHBondContact O-CG2 3.45Å; F403-V407 PolarHBondContact O-N 2.86Å; F403-L487 HydrophobicContact CZ-CB 4.34Å; F403-Q488 HydrophobicContact CD2-CG 4.5Å; F403-Q488 HydrophobicContact CE2-CG 4.13Å; F403-W495 AromaticContact CE1-CH2 3.76Å; F403-W495 HydrophobicContact CE1-CH2 3.76Å; F403-W495 HydrophobicContact CE1-CZ2 4.05Å; F403-W495 HydrophobicContact CE1-CZ3 4.43Å; F403-W495 AromaticContact CZ-CH2 3.8Å; F403-W495 HydrophobicContact CZ-CH2 3.8Å; F403-W495 AromaticContact CZ-CZ2 3.59Å; F403-W495 HydrophobicContact CZ-CZ2 3.59Å
404	H	95.4	Very high	92.1	Very high	0 Å²	0	11.2 Å²	11.2	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-55.4	-46.4	175.9	-63.6	-179.5	0	0	0	111.5	Y284 Q400 M401 Q406 V407 S408 M417 L420 N421	Y284-H404 AromaticContact CE2-NE2 3.12Å; Y284-H404 WeakPolarHBondContact CE2-NE2 3.48Å; Y284-H404 AromaticContact CZ-NE2 3.37Å; Y284-H404 PolarHBondContact OH-CD2 3.19Å; Y284-H404 PolarHBondContact OH-NE2 3.47Å; Q400-H404 PolarHBondContact O-CD2 3.18Å; Q400-H404 VanDerWaalsContact O-CG 3.31Å; Q400-H404 PolarHBondContact O-N 3.36Å; M401-H404 PolarHBondContact O-N 2.83Å; H404-Q406 VanDerWaalsContact C-N 3.27Å; H404-Q406 PolarHBondContact O-N 3.01Å; H404-V407 PolarHBondContact O-N 3.15Å; H404-S408 VanDerWaalsContact O-CB 3.27Å; H404-S408 WeakPolarHBondContact O-CB 3.45Å; H404-S408 PolarHBondContact O-N 3.47Å; H404-S408 PolarHBondContact O-OG 3.28Å; H404-M417 HydrophobicContact CB-CE 4.12Å; H404-M417 HydrophobicContact CB-SD 3.7Å; H404-L420 HydrophobicContact CB-CB 4.47Å; H404-L420 HydrophobicContact CB-CD1 4.02Å; H404-N421 PolarHBondContact CE1-OD1 2.89Å; H404-N421 PolarHBondContact ND1-OD1 3.1Å
405	A	93.5	Very high	92	Very high	5 Å²	5	9.7 Å²	9.7	4%	0.041	5%	0.053	C	C	.	.	H	α-helix	trans	-64.1	-32	178.7	0	0	0	0	0	112.7	L163 V171 A174 M401 A402 F403 M417	L163-A405 HydrophobicContact CD2-CB 3.82Å; L163-A405 WeakPolarHBondContact CD2-O 3.36Å; V171-A405 HydrophobicContact CG2-CB 4.39Å; A174-A405 HydrophobicContact CB-CB 4.18Å; M401-A405 PolarHBondContact O-N 3.03Å; A402-A405 PolarHBondContact O-N 2.94Å; F403-A405 VanDerWaalsContact C-N 3.3Å; F403-A405 PolarHBondContact O-N 3.4Å; A405-M417 HydrophobicContact CB-CE 4.29Å; A405-M417 HydrophobicContact CB-SD 4.38Å
406	Q	92.4	Very high	91.9	Very high	18 Å²	18	8.9 Å²	8.9	8%	0.084	5%	0.047	C	C	.	.	H	α-helix	trans	-78	-28.3	179	-72.1	178.4	21.4	0	0	114.3	V171 G336 A402 F403 H404	V171-Q406 HydrophobicContact CG1-CG 3.94Å; G336-Q406 PolarHBondContact O-NE2 3.34Å; A402-Q406 VanDerWaalsContact O-CG 3.29Å; A402-Q406 WeakPolarHBondContact O-CG 3.47Å; A402-Q406 PolarHBondContact O-N 3.48Å; A402-Q406 VanDerWaalsContact O-N 3.08Å; F403-Q406 PolarHBondContact O-N 3Å; H404-Q406 VanDerWaalsContact C-N 3.27Å; H404-Q406 PolarHBondContact O-N 3.01Å
407	V	92.9	Very high	91.8	Very high	7 Å²	7	8.7 Å²	8.7	4%	0.042	5%	0.046	C	C	.	.	H	α-helix	trans	-99.6	-22.5	-176.5	-58.4	0	0	0	0	113.9	F403 H404 D409 L420 W495 W496	F403-V407 HydrophobicContact CD1-CG1 4.41Å; F403-V407 HydrophobicContact CD2-CG1 4.17Å; F403-V407 HydrophobicContact CE1-CG1 3.97Å; F403-V407 HydrophobicContact CE1-CG2 4.42Å; F403-V407 HydrophobicContact CE2-CG1 3.7Å; F403-V407 HydrophobicContact CZ-CG1 3.61Å; F403-V407 WeakPolarHBondContact O-CG2 3.45Å; F403-V407 PolarHBondContact O-N 2.86Å; H404-V407 PolarHBondContact O-N 3.15Å; V407-D409 PolarHBondContact O-N 3.19Å; V407-L420 HydrophobicContact CG2-CD1 3.88Å; V407-W495 HydrophobicContact CB-CB 4.23Å; V407-W495 HydrophobicContact CB-CD2 3.72Å; V407-W495 HydrophobicContact CB-CE3 3.9Å; V407-W495 HydrophobicContact CB-CG 3.88Å; V407-W495 HydrophobicContact CG1-CD2 3.85Å; V407-W495 HydrophobicContact CG1-CE3 4.29Å; V407-W495 HydrophobicContact CG1-CG 4.14Å; V407-W495 HydrophobicContact CG1-CZ2 4.25Å; V407-W495 HydrophobicContact CG2-CD2 4.32Å; V407-W495 HydrophobicContact CG2-CE3 3.97Å; V407-W495 HydrophobicContact CG2-CZ3 4.29Å; V407-W496 PolarHBondContact O-NE1 3.31Å; V407-W496 VanDerWaalsContact O-NE1 3.09Å
408	S	92.2	Very high	91.7	Very high	4 Å²	4	5.9 Å²	5.9	3%	0.028	3%	0.034	C	C	.	.	S	Bend	trans	-65.1	133.9	-178.2	-66.2	0	0	0	0	111.6	H404 P410 M417	H404-S408 VanDerWaalsContact O-CB 3.27Å; H404-S408 WeakPolarHBondContact O-CB 3.45Å; H404-S408 PolarHBondContact O-N 3.47Å; H404-S408 PolarHBondContact O-OG 3.28Å; S408-P410 WeakPolarHBondContact O-CD 3.49Å; S408-M417 PolarHBondContact OG-SD 3.02Å
409	D	86.5	Confident	91.6	Very high	15 Å²	15	6 Å²	6	8%	0.08	3%	0.034	C	C	.	.			trans	-68.7	120.9	174.9	-175.7	-11.9	0	0	0	110.4	V407 V411 V412 G413 Y416 W496	V407-D409 PolarHBondContact O-N 3.19Å; D409-V411 PolarHBondContact O-N 3.3Å; D409-V411 VanDerWaalsContact O-N 3.12Å; D409-V411 VanDerWaalsContact OD1-CB 3.27Å; D409-V411 WeakPolarHBondContact OD1-CB 3.35Å; D409-V411 WeakPolarHBondContact OD1-CG2 3.25Å; D409-V411 PolarHBondContact OD1-N 3.38Å; D409-V412 HydrophobicContact CB-CG2 4.16Å; D409-V412 CarbonylContact O-C 3.48Å; D409-V412 PolarHBondContact O-N 3Å; D409-V412 VanDerWaalsContact O-N 3.16Å; D409-G413 WeakPolarHBondContact O-CA 3.25Å; D409-G413 PolarHBondContact O-N 2.9Å; D409-Y416 HydrophobicContact CB-CD2 4.03Å; D409-Y416 HydrophobicContact CB-CE2 4.4Å; D409-W496 HydrophobicContact CB-CB 4.48Å; D409-W496 HydrophobicContact CB-CD2 4.47Å; D409-W496 HydrophobicContact CB-CG 3.95Å
410	P	83.5	Confident	91.6	Very high	28 Å²	28	6.1 Å²	6.1	18%	0.182	4%	0.035	C	C	.	.	G	3₁₀ helix	trans	-59.4	-20.6	175.9	-23.3	34.7	0	0	0	114.6	R98 T164 S408	R98-P410 PolarHBondContact NH2-O 3.17Å; T164-P410 HydrophobicContact CG2-CB 4.08Å; S408-P410 WeakPolarHBondContact O-CD 3.49Å
411	V	82.7	Confident	91.4	Very high	23 Å²	23	6.4 Å²	6.4	14%	0.139	4%	0.037	C	C	.	.	G	3₁₀ helix	trans	-65.3	-42.8	175.7	177.9	0	0	0	0	111.2	R98 F255 M258 D409	R98-V411 PolarHBondContact NH1-O 3.18Å; F255-V411 HydrophobicContact CD1-CB 4.24Å; F255-V411 HydrophobicContact CD1-CG1 4.25Å; F255-V411 HydrophobicContact CD1-CG2 4.04Å; F255-V411 HydrophobicContact CE1-CB 4.21Å; F255-V411 HydrophobicContact CE1-CG2 3.79Å; M258-V411 HydrophobicContact CG-CG1 3.52Å; M258-V411 HydrophobicContact SD-CG1 4.28Å; D409-V411 PolarHBondContact O-N 3.3Å; D409-V411 VanDerWaalsContact O-N 3.12Å; D409-V411 VanDerWaalsContact OD1-CB 3.27Å; D409-V411 WeakPolarHBondContact OD1-CB 3.35Å; D409-V411 WeakPolarHBondContact OD1-CG2 3.25Å; D409-V411 PolarHBondContact OD1-N 3.38Å
412	V	85.4	Confident	91.3	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	5%	0.045	C	C	.	.	G	3₁₀ helix	trans	-122.3	38.6	176.6	-74.3	0	0	0	0	111.8	M258 T264 I271 D409 G414 T415 Y416	M258-V412 HydrophobicContact CE-CG1 3.23Å; M258-V412 HydrophobicContact SD-CG1 4.49Å; T264-V412 HydrophobicContact CG2-CG1 3.96Å; I271-V412 HydrophobicContact CD1-CG2 3.66Å; D409-V412 HydrophobicContact CB-CG2 4.16Å; D409-V412 CarbonylContact O-C 3.48Å; D409-V412 PolarHBondContact O-N 3Å; D409-V412 VanDerWaalsContact O-N 3.16Å; V412-G414 VanDerWaalsContact C-N 3.29Å; V412-G414 PolarHBondContact O-N 3.44Å; V412-T415 PolarHBondContact O-N 3.28Å; V412-Y416 HydrophobicContact CG2-CD2 4.47Å; V412-Y416 WeakPolarHBondContact O-CB 3.07Å; V412-Y416 PolarHBondContact O-N 3.23Å
413	G	86.3	Confident	91.1	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.052	C	C	.	.	H	α-helix	trans	-62.7	-33.3	-166.6	0	0	0	0	0	114	C160 D409 M417	C160-G413 WeakPolarHBondContact SG-CA 3.31Å; D409-G413 WeakPolarHBondContact O-CA 3.25Å; D409-G413 PolarHBondContact O-N 2.9Å; G413-M417 WeakPolarHBondContact O-CB 3.46Å; G413-M417 WeakPolarHBondContact O-CG 3.45Å; G413-M417 PolarHBondContact O-N 3.37Å
414	G	88.7	Confident	91	Very high	0 Å²	0	8.8 Å²	8.8	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-70.4	-45.6	-178.7	0	0	0	0	0	110.3	D89 C160 V412 T418	D89-G414 PolarHBondContact OD2-N 2.54Å; C160-G414 PolarHBondContact SG-N 3.33Å; V412-G414 VanDerWaalsContact C-N 3.29Å; V412-G414 PolarHBondContact O-N 3.44Å; G414-T418 WeakPolarHBondContact O-CB 3.25Å; G414-T418 PolarHBondContact O-N 3.22Å; G414-T418 PolarHBondContact O-OG1 3.27Å
415	T	92.2	Very high	90.8	Very high	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-61.6	-47.4	173.8	-58	0	0	0	0	111.7	A85 P86 D89 L268 V412 L419	A85-T415 VanDerWaalsContact C-OG1 3.29Å; A85-T415 PolarHBondContact O-OG1 2.84Å; P86-T415 WeakPolarHBondContact CA-OG1 3.45Å; P86-T415 HydrophobicContact CG-CG2 3.85Å; D89-T415 WeakPolarHBondContact OD2-CB 3.16Å; D89-T415 PolarHBondContact OD2-N 3.46Å; D89-T415 PolarHBondContact OD2-OG1 2.71Å; L268-T415 HydrophobicContact CB-CG2 3.89Å; L268-T415 HydrophobicContact CD1-CG2 3.78Å; L268-T415 HydrophobicContact CD2-CG2 4.14Å; L268-T415 HydrophobicContact CG-CG2 4.14Å; V412-T415 PolarHBondContact O-N 3.28Å; T415-L419 VanDerWaalsContact O-CB 3.3Å; T415-L419 WeakPolarHBondContact O-CB 3.34Å; T415-L419 PolarHBondContact O-N 3.13Å
416	Y	93.1	Very high	90.7	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-67.2	-51.2	-177.3	-152.7	-43.9	0	0	0	111.3	I271 V277 D409 V412 T418 L419 L420 W495	I271-Y416 HydrophobicContact CB-CE2 4.41Å; I271-Y416 HydrophobicContact CD1-CD2 3.56Å; I271-Y416 HydrophobicContact CD1-CE2 3.89Å; I271-Y416 HydrophobicContact CD1-CG 4.27Å; I271-Y416 HydrophobicContact CG1-CD2 4.11Å; I271-Y416 HydrophobicContact CG1-CE2 3.9Å; I271-Y416 HydrophobicContact CG2-CD1 4.2Å; I271-Y416 HydrophobicContact CG2-CD2 3.99Å; I271-Y416 HydrophobicContact CG2-CE1 3.77Å; I271-Y416 HydrophobicContact CG2-CE2 3.58Å; I271-Y416 HydrophobicContact CG2-CG 4.28Å; I271-Y416 VanDerWaalsContact CG2-CZ 3.45Å; V277-Y416 HydrophobicContact CG2-CE1 4.39Å; V277-Y416 WeakPolarHBondContact CG2-OH 3.4Å; D409-Y416 HydrophobicContact CB-CD2 4.03Å; D409-Y416 HydrophobicContact CB-CE2 4.4Å; V412-Y416 HydrophobicContact CG2-CD2 4.47Å; V412-Y416 WeakPolarHBondContact O-CB 3.07Å; V412-Y416 PolarHBondContact O-N 3.23Å; Y416-T418 VanDerWaalsContact C-N 3.3Å; Y416-T418 PolarHBondContact O-N 2.7Å; Y416-L419 WeakPolarHBondContact O-CB 3.32Å; Y416-L419 PolarHBondContact O-N 3.34Å; Y416-L420 HydrophobicContact CD1-CD1 3.82Å; Y416-L420 HydrophobicContact CD1-CD2 4.49Å; Y416-L420 HydrophobicContact CD1-CG 3.85Å; Y416-L420 HydrophobicContact CE1-CD1 3.73Å; Y416-L420 HydrophobicContact CE1-CD2 4.11Å; Y416-L420 HydrophobicContact CE1-CG 3.89Å; Y416-L420 PolarHBondContact O-N 2.9Å; Y416-W495 WeakPolarHBondContact CE2-O 3.49Å; Y416-W495 PolarHBondContact OH-O 3.46Å
417	M	93.1	Very high	90.8	Very high	5 Å²	5	15.7 Å²	15.7	3%	0.025	9%	0.088	C	C	.	.	H	α-helix	trans	-58	-45.3	176.6	-74.9	-69.5	-70.3	0	0	111	D159 L163 M401 H404 A405 S408 G413 L419 L420 N421	D159-M417 HydrophobicContact CB-CB 4.42Å; L163-M417 HydrophobicContact CD1-CG 4.03Å; L163-M417 HydrophobicContact CD2-CG 4.49Å; L163-M417 HydrophobicContact CD2-SD 4.34Å; M401-M417 HydrophobicContact CE-CE 4.32Å; H404-M417 HydrophobicContact CB-CE 4.12Å; H404-M417 HydrophobicContact CB-SD 3.7Å; A405-M417 HydrophobicContact CB-CE 4.29Å; A405-M417 HydrophobicContact CB-SD 4.38Å; S408-M417 PolarHBondContact OG-SD 3.02Å; G413-M417 WeakPolarHBondContact O-CB 3.46Å; G413-M417 WeakPolarHBondContact O-CG 3.45Å; G413-M417 PolarHBondContact O-N 3.37Å; M417-L419 PolarHBondContact O-N 2.93Å; M417-L420 PolarHBondContact O-N 3.24Å; M417-N421 VanDerWaalsContact O-CB 3.26Å; M417-N421 WeakPolarHBondContact O-CB 3.26Å; M417-N421 PolarHBondContact O-N 2.66Å; M417-N421 PolarHBondContact O-ND2 3.37Å; M417-N421 PolarHBondContact O-OD1 3.3Å
418	T	93.3	Very high	90.6	Very high	0 Å²	0	16 Å²	16	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-62	-42.5	178	-66.2	0	0	0	0	112	K81 L82 A85 G414 Y416 T422	K81-T418 HydrophobicContact CB-CG2 4.4Å; K81-T418 HydrophobicContact CD-CG2 3.75Å; K81-T418 HydrophobicContact CG-CG2 3.59Å; L82-T418 HydrophobicContact CB-CG2 3.9Å; L82-T418 HydrophobicContact CD1-CG2 4.19Å; A85-T418 HydrophobicContact CB-CG2 4.25Å; G414-T418 WeakPolarHBondContact O-CB 3.25Å; G414-T418 PolarHBondContact O-N 3.22Å; G414-T418 PolarHBondContact O-OG1 3.27Å; Y416-T418 VanDerWaalsContact C-N 3.3Å; Y416-T418 PolarHBondContact O-N 2.7Å; T418-T422 VanDerWaalsContact O-CB 3.24Å; T418-T422 WeakPolarHBondContact O-CB 3.38Å; T418-T422 PolarHBondContact O-N 2.84Å; T418-T422 PolarHBondContact O-OG1 3.48Å
419	L	94.4	Very high	90.5	Very high	2 Å²	2	20.9 Å²	20.9	1%	0.01	12%	0.118	C	C	.	.	H	α-helix	trans	-57.6	-54.8	175.6	172.7	66.9	0	0	0	110.6	L82 L268 I271 M272 T415 Y416 M417 N421 T422 L423	L82-L419 HydrophobicContact CD1-CB 3.91Å; L82-L419 HydrophobicContact CD1-CD1 4.33Å; L82-L419 HydrophobicContact CD2-CD1 3.9Å; L268-L419 HydrophobicContact CD1-CB 4.14Å; L268-L419 HydrophobicContact CD1-CD1 4.08Å; L268-L419 HydrophobicContact CD1-CD2 3.77Å; L268-L419 HydrophobicContact CD1-CG 4.19Å; I271-L419 HydrophobicContact CG2-CD2 3.77Å; M272-L419 HydrophobicContact CG-CD1 3.89Å; M272-L419 HydrophobicContact CG-CD2 3.68Å; M272-L419 HydrophobicContact CG-CG 4.41Å; M272-L419 HydrophobicContact SD-CD1 3.85Å; T415-L419 VanDerWaalsContact O-CB 3.3Å; T415-L419 WeakPolarHBondContact O-CB 3.34Å; T415-L419 PolarHBondContact O-N 3.13Å; Y416-L419 WeakPolarHBondContact O-CB 3.32Å; Y416-L419 PolarHBondContact O-N 3.34Å; M417-L419 PolarHBondContact O-N 2.93Å; L419-N421 PolarHBondContact O-N 3.36Å; L419-T422 WeakPolarHBondContact O-CB 3.4Å; L419-T422 PolarHBondContact O-N 3.4Å; L419-L423 HydrophobicContact CD1-CD1 3.5Å; L419-L423 HydrophobicContact CD1-CG 4.25Å; L419-L423 HydrophobicContact CD2-CD1 4.49Å; L419-L423 HydrophobicContact CG-CD1 3.65Å; L419-L423 WeakPolarHBondContact O-CD1 3.5Å; L419-L423 WeakPolarHBondContact O-CG 3.22Å; L419-L423 PolarHBondContact O-N 2.83Å
420	L	94.9	Very high	90.9	Very high	2 Å²	2	24.6 Å²	24.6	1%	0.01	13%	0.131	C	C	.	.	H	α-helix	trans	-62.6	-42.6	-178	-65	-175.5	0	0	0	112.1	V277 L280 H404 V407 Y416 M417 T422 L423 A424	V277-L420 HydrophobicContact CG1-CD2 4.46Å; L280-L420 HydrophobicContact CD2-CD1 4.46Å; L280-L420 HydrophobicContact CD2-CD2 3.98Å; H404-L420 HydrophobicContact CB-CB 4.47Å; H404-L420 HydrophobicContact CB-CD1 4.02Å; V407-L420 HydrophobicContact CG2-CD1 3.88Å; Y416-L420 HydrophobicContact CD1-CD1 3.82Å; Y416-L420 HydrophobicContact CD1-CD2 4.49Å; Y416-L420 HydrophobicContact CD1-CG 3.85Å; Y416-L420 HydrophobicContact CE1-CD1 3.73Å; Y416-L420 HydrophobicContact CE1-CD2 4.11Å; Y416-L420 HydrophobicContact CE1-CG 3.89Å; Y416-L420 PolarHBondContact O-N 2.9Å; M417-L420 PolarHBondContact O-N 3.24Å; L420-T422 VanDerWaalsContact C-N 3.34Å; L420-T422 PolarHBondContact O-N 2.91Å; L420-L423 PolarHBondContact O-N 2.92Å; L420-A424 WeakPolarHBondContact O-CB 3.49Å; L420-A424 PolarHBondContact O-N 2.81Å
421	N	92.7	Very high	91.5	Very high	10 Å²	10	23.5 Å²	23.5	5%	0.053	12%	0.123	C	C	.	.	H	α-helix	trans	-62.3	-42.5	176.1	-68.7	-12.2	0	0	0	111.3	M401 H404 M417 L419 A424 N425	M401-N421 PolarHBondContact SD-OD1 2.87Å; H404-N421 PolarHBondContact CE1-OD1 2.89Å; H404-N421 PolarHBondContact ND1-OD1 3.1Å; M417-N421 VanDerWaalsContact O-CB 3.26Å; M417-N421 WeakPolarHBondContact O-CB 3.26Å; M417-N421 PolarHBondContact O-N 2.66Å; M417-N421 PolarHBondContact O-ND2 3.37Å; M417-N421 PolarHBondContact O-OD1 3.3Å; L419-N421 PolarHBondContact O-N 3.36Å; N421-A424 PolarHBondContact O-N 3.41Å; N421-N425 WeakPolarHBondContact O-CB 3.35Å; N421-N425 PolarHBondContact O-N 3.3Å; N421-N425 PolarHBondContact O-ND2 3.33Å
422	T	92	Very high	92.1	Very high	36 Å²	36	23.9 Å²	23.9	22%	0.221	13%	0.126	C	C	.	.	H	α-helix	trans	-62.4	-45.7	177.5	-58.5	0	0	0	0	111.1	T418 L419 L420 N425 L426	T418-T422 VanDerWaalsContact O-CB 3.24Å; T418-T422 WeakPolarHBondContact O-CB 3.38Å; T418-T422 PolarHBondContact O-N 2.84Å; T418-T422 PolarHBondContact O-OG1 3.48Å; L419-T422 WeakPolarHBondContact O-CB 3.4Å; L419-T422 PolarHBondContact O-N 3.4Å; L420-T422 VanDerWaalsContact C-N 3.34Å; L420-T422 PolarHBondContact O-N 2.91Å; T422-N425 PolarHBondContact O-N 3.4Å; T422-L426 WeakPolarHBondContact O-CB 3.48Å; T422-L426 PolarHBondContact O-N 3.43Å
423	L	92	Very high	92.5	Very high	28 Å²	28	27.9 Å²	27.9	15%	0.147	15%	0.151	C	C	.	.	H	α-helix	trans	-66.8	-38.4	179.7	-70.7	155.8	0	0	0	112.1	I281 L419 L420 L426 G427	I281-L423 HydrophobicContact CD1-CD1 3.63Å; I281-L423 HydrophobicContact CD1-CD2 4.23Å; I281-L423 HydrophobicContact CG1-CB 4.49Å; I281-L423 HydrophobicContact CG1-CD1 3.65Å; I281-L423 HydrophobicContact CG1-CD2 4.18Å; I281-L423 HydrophobicContact CG1-CG 4.31Å; I281-L423 HydrophobicContact CG2-CD2 4.27Å; L419-L423 HydrophobicContact CD1-CD1 3.5Å; L419-L423 HydrophobicContact CD1-CG 4.25Å; L419-L423 HydrophobicContact CD2-CD1 4.49Å; L419-L423 HydrophobicContact CG-CD1 3.65Å; L419-L423 WeakPolarHBondContact O-CD1 3.5Å; L419-L423 WeakPolarHBondContact O-CG 3.22Å; L419-L423 PolarHBondContact O-N 2.83Å; L420-L423 PolarHBondContact O-N 2.92Å; L423-L426 PolarHBondContact O-N 3.25Å; L423-G427 PolarHBondContact O-N 2.97Å
424	A	93.6	Very high	92.9	Very high	1 Å²	1	31.3 Å²	31.3	1%	0.008	17%	0.171	C	C	.	.	H	α-helix	trans	-69.2	-35.1	175.3	0	0	0	0	0	113.3	Y284 L420 N421 G428	Y284-A424 HydrophobicContact CD2-CB 3.94Å; Y284-A424 HydrophobicContact CE2-CB 4.32Å; Y284-A424 HydrophobicContact CG-CB 4.26Å; L420-A424 WeakPolarHBondContact O-CB 3.49Å; L420-A424 PolarHBondContact O-N 2.81Å; N421-A424 PolarHBondContact O-N 3.41Å; A424-G428 PolarHBondContact O-N 2.86Å
425	N	91.5	Very high	93.2	Very high	80 Å²	80	31.7 Å²	31.7	43%	0.428	17%	0.174	S	C	.	.	H	α-helix	trans	-68.3	-44.2	173	-72.4	-16	0	0	0	111	N421 T422 G427 G428 N429	N421-N425 WeakPolarHBondContact O-CB 3.35Å; N421-N425 PolarHBondContact O-N 3.3Å; N421-N425 PolarHBondContact O-ND2 3.33Å; T422-N425 PolarHBondContact O-N 3.4Å; N425-G427 VanDerWaalsContact C-N 3.29Å; N425-G427 PolarHBondContact O-N 3.49Å; N425-G428 PolarHBondContact O-N 2.64Å; N425-N429 PolarHBondContact O-N 3.38Å
426	L	92	Very high	93.2	Very high	89 Å²	89	34.9 Å²	34.9	47%	0.466	19%	0.191	S	C	.	.	H	α-helix	trans	-55.3	-47.3	174.3	179.3	61.5	0	0	0	110.8	L285 T422 L423 G428 N429 W430	L285-L426 HydrophobicContact CD2-CD2 4.04Å; L285-L426 HydrophobicContact CD2-CG 4.05Å; T422-L426 WeakPolarHBondContact O-CB 3.48Å; T422-L426 PolarHBondContact O-N 3.43Å; L423-L426 PolarHBondContact O-N 3.25Å; L426-G428 PolarHBondContact O-N 2.81Å; L426-G428 VanDerWaalsContact O-N 3.12Å; L426-N429 PolarHBondContact O-N 3.41Å; L426-N429 VanDerWaalsContact O-N 3.11Å; L426-W430 PolarHBondContact O-N 3.4Å; L426-W430 VanDerWaalsContact O-N 3.13Å
427	G	93	Very high	93.2	Very high	0 Å²	0	40 Å²	40	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-59.9	-18.1	176.2	0	0	0	0	0	115.3	Y284 L423 N425 P431	Y284-G427 WeakPolarHBondContact O-CA 3.3Å; L423-G427 PolarHBondContact O-N 2.97Å; N425-G427 VanDerWaalsContact C-N 3.29Å; N425-G427 PolarHBondContact O-N 3.49Å; G427-P431 WeakPolarHBondContact O-CD 3.39Å; G427-P431 WeakPolarHBondContact O-CG 3.32Å
428	G	90.2	Very high	93.2	Very high	13 Å²	13	40.8 Å²	40.8	13%	0.134	23%	0.228	C	C	.	.	H	α-helix	trans	-92.6	-33.4	171.6	0	0	0	0	0	114.6	K288 A424 N425 L426 V432	K288-G428 VanDerWaalsContact CD-CA 3.42Å; A424-G428 PolarHBondContact O-N 2.86Å; N425-G428 PolarHBondContact O-N 2.64Å; L426-G428 PolarHBondContact O-N 2.81Å; L426-G428 VanDerWaalsContact O-N 3.12Å; G428-V432 WeakPolarHBondContact O-CG2 3.42Å
429	N	90.5	Very high	93.2	Very high	106 Å²	106	41.8 Å²	41.8	57%	0.567	23%	0.234	S	C	*	.	H	α-helix	trans	-81.9	-44.9	-173.5	-70.1	-20.6	0	0	0	113	N425 L426 P431 V432 T433	N425-N429 PolarHBondContact O-N 3.38Å; L426-N429 PolarHBondContact O-N 3.41Å; L426-N429 VanDerWaalsContact O-N 3.11Å; N429-P431 VanDerWaalsContact C-CD 3.48Å; N429-V432 PolarHBondContact O-N 3.02Å; N429-T433 PolarHBondContact O-N 3.25Å; N429-T433 VanDerWaalsContact O-N 3.1Å; N429-T433 PolarHBondContact O-OG1 3.38Å
430	W	94.7	Very high	93	Very high	94 Å²	94	46.9 Å²	46.9	36%	0.356	26%	0.262	S	S	.	.	H	α-helix	trans	-61.7	-39.3	-175.9	84.3	-99.7	0	0	0	113.4	L285 I289 L426 V432 T433 V434	L285-W430 VanDerWaalsContact O-CZ2 3.27Å; L285-W430 WeakPolarHBondContact O-CZ2 3.47Å; L285-W430 PolarHBondContact O-NE1 3.48Å; I289-W430 HydrophobicContact CD1-CH2 3.78Å; I289-W430 HydrophobicContact CD1-CZ2 3.71Å; I289-W430 HydrophobicContact CG1-CH2 3.94Å; I289-W430 HydrophobicContact CG1-CZ2 3.75Å; L426-W430 PolarHBondContact O-N 3.4Å; L426-W430 VanDerWaalsContact O-N 3.13Å; W430-V432 VanDerWaalsContact C-N 3.32Å; W430-V432 PolarHBondContact O-N 3.38Å; W430-T433 PolarHBondContact O-N 2.87Å; W430-V434 HydrophobicContact CE3-CG2 3.79Å; W430-V434 HydrophobicContact CZ3-CG2 3.97Å; W430-V434 WeakPolarHBondContact O-CG2 3.25Å; W430-V434 PolarHBondContact O-N 3.11Å
431	P	96.2	Very high	92.8	Very high	4 Å²	4	50.9 Å²	50.9	3%	0.026	29%	0.29	C	S	.	.	H	α-helix	trans	-66.5	-36.5	178.7	-19.9	34.2	0	0	0	112	I289 A292 G427 N429 V434 A435	I289-P431 HydrophobicContact CG1-CB 4.18Å; I289-P431 HydrophobicContact CG1-CG 4.02Å; A292-P431 HydrophobicContact CB-CB 3.72Å; G427-P431 WeakPolarHBondContact O-CD 3.39Å; G427-P431 WeakPolarHBondContact O-CG 3.32Å; N429-P431 VanDerWaalsContact C-CD 3.48Å; P431-V434 PolarHBondContact O-N 2.81Å; P431-A435 WeakPolarHBondContact O-CB 3.2Å; P431-A435 PolarHBondContact O-N 2.89Å
432	V	94.7	Very high	92.7	Very high	31 Å²	31	54.3 Å²	54.3	19%	0.188	31%	0.306	C	S	.	.	H	α-helix	trans	-62.4	-44.5	175.9	168.3	0	0	0	0	110.5	D295 G428 N429 W430 V434 A435 L436	D295-V432 HydrophobicContact CB-CG2 4.43Å; G428-V432 WeakPolarHBondContact O-CG2 3.42Å; N429-V432 PolarHBondContact O-N 3.02Å; W430-V432 VanDerWaalsContact C-N 3.32Å; W430-V432 PolarHBondContact O-N 3.38Å; V432-V434 PolarHBondContact O-N 3.09Å; V432-A435 PolarHBondContact O-N 3.4Å; V432-L436 HydrophobicContact CG1-CD1 3.87Å; V432-L436 HydrophobicContact CG1-CG 4.47Å; V432-L436 WeakPolarHBondContact O-CB 3.28Å; V432-L436 WeakPolarHBondContact O-CG 3.35Å; V432-L436 PolarHBondContact O-N 3.1Å
433	T	93.3	Very high	92.6	Very high	85 Å²	85	53.5 Å²	53.5	52%	0.521	30%	0.304	S	S	.	.	H	α-helix	trans	-58.2	-48.1	174.6	-56.2	0	0	0	0	111.5	N429 W430 A435 L436 T437	N429-T433 PolarHBondContact O-N 3.25Å; N429-T433 VanDerWaalsContact O-N 3.1Å; N429-T433 PolarHBondContact O-OG1 3.38Å; W430-T433 PolarHBondContact O-N 2.87Å; T433-A435 PolarHBondContact O-N 2.94Å; T433-L436 PolarHBondContact O-N 3.31Å; T433-T437 WeakPolarHBondContact O-CG2 3.49Å; T433-T437 PolarHBondContact O-N 2.78Å; T433-T437 PolarHBondContact O-OG1 2.93Å
434	V	94.8	Very high	92.5	Very high	72 Å²	72	59 Å²	59	44%	0.436	32%	0.323	S	S	.	.	H	α-helix	trans	-61	-47.8	178.5	173.2	0	0	0	0	110.9	W430 P431 V432 L436 T437 S438	W430-V434 HydrophobicContact CE3-CG2 3.79Å; W430-V434 HydrophobicContact CZ3-CG2 3.97Å; W430-V434 WeakPolarHBondContact O-CG2 3.25Å; W430-V434 PolarHBondContact O-N 3.11Å; P431-V434 PolarHBondContact O-N 2.81Å; V432-V434 PolarHBondContact O-N 3.09Å; V434-L436 PolarHBondContact O-N 3.46Å; V434-T437 WeakPolarHBondContact CA-OG1 3.45Å; V434-T437 PolarHBondContact O-N 3.48Å; V434-T437 VanDerWaalsContact O-N 3.13Å; V434-T437 PolarHBondContact O-OG1 3.35Å; V434-S438 WeakPolarHBondContact O-CB 3.48Å; V434-S438 PolarHBondContact O-N 2.79Å; V434-S438 PolarHBondContact O-OG 3.42Å; V434-S438 VanDerWaalsContact O-OG 3.05Å
435	A	95.2	Very high	92.2	Very high	7 Å²	7	64.7 Å²	64.7	6%	0.058	35%	0.345	C	S	.	.	H	α-helix	trans	-58.6	-44.6	179.3	0	0	0	0	0	112.3	A292 I297 P431 V432 T433 S438 V439 L465	A292-A435 HydrophobicContact CB-CB 3.91Å; I297-A435 HydrophobicContact CD1-CB 4.11Å; P431-A435 WeakPolarHBondContact O-CB 3.2Å; P431-A435 PolarHBondContact O-N 2.89Å; V432-A435 PolarHBondContact O-N 3.4Å; T433-A435 PolarHBondContact O-N 2.94Å; A435-S438 PolarHBondContact O-N 2.99Å; A435-S438 PolarHBondContact O-OG 3.46Å; A435-V439 WeakPolarHBondContact O-CB 3.38Å; A435-V439 PolarHBondContact O-N 3.1Å; A435-L465 HydrophobicContact CB-CD1 4.32Å; A435-L465 WeakPolarHBondContact O-CD1 3.13Å
436	L	92.7	Very high	91.8	Very high	68 Å²	68	63.6 Å²	63.6	36%	0.356	34%	0.341	S	S	.	.	H	α-helix	trans	-61.7	-41.5	175.4	-76.8	166.7	0	0	0	112	I297 L300 V432 T433 V434 V439	I297-L436 HydrophobicContact CG1-CD2 3.98Å; I297-L436 HydrophobicContact CG1-CG 4.44Å; L300-L436 HydrophobicContact CD1-CD2 3.64Å; V432-L436 HydrophobicContact CG1-CD1 3.87Å; V432-L436 HydrophobicContact CG1-CG 4.47Å; V432-L436 WeakPolarHBondContact O-CB 3.28Å; V432-L436 WeakPolarHBondContact O-CG 3.35Å; V432-L436 PolarHBondContact O-N 3.1Å; T433-L436 PolarHBondContact O-N 3.31Å; V434-L436 PolarHBondContact O-N 3.46Å; L436-V439 WeakPolarHBondContact O-CG1 3.33Å
437	T	93.3	Very high	91.4	Very high	107 Å²	107	62.6 Å²	62.6	66%	0.656	34%	0.341	S	S	*	.	H	α-helix	trans	-73.5	-28.1	178.3	55.4	0	0	0	0	113.5	T433 V434	T433-T437 WeakPolarHBondContact O-CG2 3.49Å; T433-T437 PolarHBondContact O-N 2.78Å; T433-T437 PolarHBondContact O-OG1 2.93Å; V434-T437 WeakPolarHBondContact CA-OG1 3.45Å; V434-T437 PolarHBondContact O-N 3.48Å; V434-T437 VanDerWaalsContact O-N 3.13Å; V434-T437 PolarHBondContact O-OG1 3.35Å
438	S	93.3	Very high	90.7	Very high	22 Å²	22	66.1 Å²	66.1	15%	0.154	36%	0.362	C	S	.	.	H	α-helix	trans	-92.5	-15.4	-176.2	65.6	0	0	0	0	114	V434 A435 D440 S441 M442	V434-S438 WeakPolarHBondContact O-CB 3.48Å; V434-S438 PolarHBondContact O-N 2.79Å; V434-S438 PolarHBondContact O-OG 3.42Å; V434-S438 VanDerWaalsContact O-OG 3.05Å; A435-S438 PolarHBondContact O-N 2.99Å; A435-S438 PolarHBondContact O-OG 3.46Å; S438-D440 VanDerWaalsContact C-N 3.3Å; S438-D440 PolarHBondContact O-N 3.38Å; S438-S441 PolarHBondContact O-N 3.44Å; S438-S441 PolarHBondContact O-OG 3.49Å; S438-M442 VanDerWaalsContact O-CG 3.3Å; S438-M442 WeakPolarHBondContact O-CG 3.46Å; S438-M442 PolarHBondContact O-N 3.16Å
439	V	93	Very high	90.1	Very high	20 Å²	20	71.2 Å²	71.2	12%	0.121	40%	0.396	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55	-42.2	-171.3	69.7	0	0	0	0	113.1	I297 A435 L436 M442 A443 G461 L465	I297-V439 HydrophobicContact CD1-CB 4.08Å; I297-V439 HydrophobicContact CD1-CG2 4.03Å; I297-V439 HydrophobicContact CG2-CG2 4.48Å; A435-V439 WeakPolarHBondContact O-CB 3.38Å; A435-V439 PolarHBondContact O-N 3.1Å; L436-V439 WeakPolarHBondContact O-CG1 3.33Å; V439-M442 PolarHBondContact O-N 2.94Å; V439-A443 PolarHBondContact O-N 3.28Å; V439-G461 WeakPolarHBondContact O-CA 3.49Å; V439-L465 HydrophobicContact CB-CD1 3.99Å; V439-L465 HydrophobicContact CG2-CD1 4.17Å
440	D	89.5	Confident	89.2	Confident	110 Å²	110	74.5 Å²	74.5	59%	0.588	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.9	-35.3	180	-71.7	-33.6	0	0	0	112.5	S438 M442 A443	S438-D440 VanDerWaalsContact C-N 3.3Å; S438-D440 PolarHBondContact O-N 3.38Å; D440-M442 VanDerWaalsContact C-N 3.28Å; D440-M442 PolarHBondContact O-N 2.97Å; D440-A443 WeakPolarHBondContact O-CB 3.03Å; D440-A443 PolarHBondContact O-N 3.43Å
441	S	90.2	Very high	87.7	Confident	86 Å²	86	72.7 Å²	72.7	60%	0.601	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.3	-24.4	177.6	69.9	0	0	0	0	113.1	S438 A443	S438-S441 PolarHBondContact O-N 3.44Å; S438-S441 PolarHBondContact O-OG 3.49Å; S441-A443 VanDerWaalsContact C-N 3.32Å
442	M	90.8	Very high	86.1	Confident	81 Å²	81	77.1 Å²	77.1	40%	0.399	44%	0.436	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-5.3	177.8	-65.4	-67.3	130.9	0	0	112.6	S438 V439 D440 V464 L465	S438-M442 VanDerWaalsContact O-CG 3.3Å; S438-M442 WeakPolarHBondContact O-CG 3.46Å; S438-M442 PolarHBondContact O-N 3.16Å; V439-M442 PolarHBondContact O-N 2.94Å; D440-M442 VanDerWaalsContact C-N 3.28Å; D440-M442 PolarHBondContact O-N 2.97Å; M442-V464 HydrophobicContact CB-CB 4.49Å; M442-V464 HydrophobicContact CB-CG1 4.47Å; M442-L465 HydrophobicContact CG-CD2 4.08Å; M442-L465 HydrophobicContact CG-CG 4.35Å
443	A	90.6	Very high	84.9	Confident	20 Å²	20	81.9 Å²	81.9	17%	0.165	47%	0.465	C	S	.	.			trans	-75.8	130.7	177.6	0	0	0	0	0	110.8	V439 D440 S441 V457 V459	V439-A443 PolarHBondContact O-N 3.28Å; D440-A443 WeakPolarHBondContact O-CB 3.03Å; D440-A443 PolarHBondContact O-N 3.43Å; S441-A443 VanDerWaalsContact C-N 3.32Å; A443-V457 HydrophobicContact CB-CG1 4.29Å; A443-V459 CarbonylContact C-O 3.19Å; A443-V459 WeakPolarHBondContact CA-O 3.24Å
444	Y	89.1	Confident	83.9	Confident	143 Å²	143	87.3 Å²	87.3	56%	0.561	48%	0.476	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-88.2	120.6	173.5	-174.6	-110.7	0	0	0	109.6	V446 L458 V459	Y444-V446 HydrophobicContact CE1-CG2 3.87Å; Y444-L458 HydrophobicContact CD1-CB 4.05Å; Y444-L458 HydrophobicContact CD1-CD1 4.13Å; Y444-L458 HydrophobicContact CE1-CD1 3.89Å; Y444-L458 PolarHBondContact O-N 3.3Å; Y444-V459 PolarHBondContact N-O 3.13Å; Y444-V459 PolarHBondContact O-N 3.12Å
445	R	87.5	Confident	83.1	Confident	120 Å²	120	86 Å²	86	45%	0.453	47%	0.47	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.6	139.2	-175.3	-54.3	-174.2	179.1	144.2	-0.7	110.5	C455 E456 V457	R445-C455 HydrophobicContact CB-CB 3.91Å; R445-E456 CarbonylContact C-O 3.46Å; R445-E456 VanDerWaalsContact CA-O 3.24Å; R445-E456 WeakPolarHBondContact CA-O 3.2Å; R445-V457 HydrophobicContact CG-CG2 4.09Å
446	V	84.3	Confident	82.4	Confident	57 Å²	57	92.1 Å²	92.1	35%	0.345	50%	0.497	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-115	126.2	172.6	174.5	0	0	0	0	108.5	Y444 C455 E456 L458	Y444-V446 HydrophobicContact CE1-CG2 3.87Å; V446-C455 CarbonylContact O-C 3.58Å; V446-C455 WeakPolarHBondContact O-CA 3.43Å; V446-E456 PolarHBondContact N-O 3.33Å; V446-E456 PolarHBondContact O-N 3.03Å; V446-L458 HydrophobicContact CB-CD1 4.13Å; V446-L458 HydrophobicContact CB-CG 4.45Å; V446-L458 HydrophobicContact CG2-CD1 3.36Å; V446-L458 HydrophobicContact CG2-CG 4.08Å
447	C	82.4	Confident	81.9	Confident	69 Å²	69	92.1 Å²	92.1	47%	0.466	50%	0.5	S	S	.	.			trans	-106.9	123.9	178.7	-39.6	0	0	0	0	107.9	C455	C447-C455 HydrophobicContact CB-CB 3.94Å; C447-C455 WeakPolarHBondContact CB-SG 3.12Å; C447-C455 WeakPolarHBondContact SG-CB 3.2Å; C447-C455 CovalentContact SG-SG 2.03Å; C447-C455 PolarHBondContact SG-SG 3.29Å
448	T	79.3	Confident	81.5	Confident	73 Å²	73	91.8 Å²	91.8	45%	0.448	49%	0.493	S	S	.	.			trans	-83.7	157.6	171.9	57.5	0	0	0	0	110.1	E450 T451	T448-E450 PolarHBondContact O-N 3.12Å; T448-T451 CarbonylContact O-C 3.6Å; T448-T451 PolarHBondContact O-N 3.49Å; T448-T451 PolarHBondContact OG1-OG1 3.21Å
449	S	76.3	Confident	81.2	Confident	120 Å²	120	93.6 Å²	93.6	84%	0.839	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60	-26	175.8	47.1	0	0	0	0	113.2
450	E	71.4	Confident	81.1	Confident	175 Å²	175	95.9 Å²	95.9	82%	0.818	51%	0.513	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.3	-27.2	-179.2	-65.6	-178.7	172.9	0	0	113	T448	T448-E450 PolarHBondContact O-N 3.12Å
451	T	63.2	Low	81.3	Confident	57 Å²	57	90.7 Å²	90.7	35%	0.35	49%	0.486	S	S	.	.			trans	-137.2	70.2	177.7	56.4	0	0	0	0	112	T448 T453 R454	T448-T451 CarbonylContact O-C 3.6Å; T448-T451 PolarHBondContact O-N 3.49Å; T448-T451 PolarHBondContact OG1-OG1 3.21Å; T451-T453 PolarHBondContact O-N 3.21Å; T451-R454 CarbonylContact O-C 3.5Å; T451-R454 PolarHBondContact O-N 3.14Å; T451-R454 PolarHBondContact OG1-O 3.44Å
452	P	62.5	Low	81.6	Confident	96 Å²	96	86.6 Å²	86.6	62%	0.623	46%	0.457	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61	-21	-179.3	23.3	-32.7	0	0	0	113.2
453	T	70.8	Confident	81.9	Confident	131 Å²	131	84.8 Å²	84.8	80%	0.804	45%	0.446	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.2	-14.4	177.7	55	0	0	0	0	114.2	T451	T451-T453 PolarHBondContact O-N 3.21Å
454	R	71	Confident	82.1	Confident	199 Å²	199	85.9 Å²	85.9	75%	0.751	45%	0.451	S	S	*	.	S	Bend	trans	-122.3	82.9	178.9	-63.4	-177.5	-179.6	174.8	0.7	109	T451	T451-R454 CarbonylContact O-C 3.5Å; T451-R454 PolarHBondContact O-N 3.14Å; T451-R454 PolarHBondContact OG1-O 3.44Å
455	C	78.1	Confident	82.5	Confident	45 Å²	45	80.3 Å²	80.3	30%	0.304	43%	0.43	S	S	.	.			trans	-75.5	135.3	173.4	-50	0	0	0	0	110.1	R445 V446 C447	R445-C455 HydrophobicContact CB-CB 3.91Å; V446-C455 CarbonylContact O-C 3.58Å; V446-C455 WeakPolarHBondContact O-CA 3.43Å; C447-C455 HydrophobicContact CB-CB 3.94Å; C447-C455 WeakPolarHBondContact CB-SG 3.12Å; C447-C455 WeakPolarHBondContact SG-CB 3.2Å; C447-C455 CovalentContact SG-SG 2.03Å; C447-C455 PolarHBondContact SG-SG 3.29Å
456	E	81.4	Confident	83	Confident	136 Å²	136	74.7 Å²	74.7	64%	0.636	41%	0.409	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-77.2	133.2	173.7	-170.4	175.6	-176.4	0	0	109.4	R445 V446 L458	R445-E456 CarbonylContact C-O 3.46Å; R445-E456 VanDerWaalsContact CA-O 3.24Å; R445-E456 WeakPolarHBondContact CA-O 3.2Å; V446-E456 PolarHBondContact N-O 3.33Å; V446-E456 PolarHBondContact O-N 3.03Å; E456-L458 PolarHBondContact O-N 3.01Å
457	V	82.9	Confident	83.6	Confident	68 Å²	68	77.5 Å²	77.5	41%	0.412	42%	0.417	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.8	109.9	177.5	-176.1	0	0	0	0	108.1	A443 R445 E460	A443-V457 HydrophobicContact CB-CG1 4.29Å; R445-V457 HydrophobicContact CG-CG2 4.09Å; V457-E460 HydrophobicContact CG1-CG 4.17Å
458	L	83.1	Confident	84.3	Confident	99 Å²	99	78 Å²	78	52%	0.518	42%	0.415	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.2	-37.6	178.4	-69.4	-176.2	0	0	0	112.4	Y444 V446 E456	Y444-L458 HydrophobicContact CD1-CB 4.05Å; Y444-L458 HydrophobicContact CD1-CD1 4.13Å; Y444-L458 HydrophobicContact CE1-CD1 3.89Å; Y444-L458 PolarHBondContact O-N 3.3Å; V446-L458 HydrophobicContact CB-CD1 4.13Å; V446-L458 HydrophobicContact CB-CG 4.45Å; V446-L458 HydrophobicContact CG2-CD1 3.36Å; V446-L458 HydrophobicContact CG2-CG 4.08Å; E456-L458 PolarHBondContact O-N 3.01Å
459	V	88	Confident	85.1	Confident	61 Å²	61	74.8 Å²	74.8	37%	0.37	40%	0.396	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.5	118.5	175.8	-175.7	0	0	0	0	108.3	A443 Y444 V464	A443-V459 CarbonylContact C-O 3.19Å; A443-V459 WeakPolarHBondContact CA-O 3.24Å; Y444-V459 PolarHBondContact N-O 3.13Å; Y444-V459 PolarHBondContact O-N 3.12Å; V459-V464 HydrophobicContact CG1-CG2 3.8Å
460	E	91.5	Very high	86.2	Confident	67 Å²	67	69.7 Å²	69.7	31%	0.313	36%	0.359	S	S	.	.			trans	-69	138.3	173.8	-57.8	-168.6	-173.2	0	0	110.7	K301 V457 Y462 Y463	K301-E460 WeakPolarHBondContact CD-OE2 3.44Å; K301-E460 VanDerWaalsContact CE-OE2 3.25Å; K301-E460 WeakPolarHBondContact CE-OE2 3.49Å; K301-E460 IonicContact NZ-OE2 2.71Å; K301-E460 PolarHBondContact NZ-OE2 3.11Å; V457-E460 HydrophobicContact CG1-CG 4.17Å; E460-Y462 PolarHBondContact O-N 3.04Å; E460-Y463 HydrophobicContact CB-CD2 3.85Å; E460-Y463 HydrophobicContact CB-CE2 4.11Å; E460-Y463 HydrophobicContact CG-CD2 4.48Å; E460-Y463 HydrophobicContact CG-CE2 4.31Å; E460-Y463 PolarHBondContact O-N 3.25Å
461	G	93.3	Very high	87.4	Confident	2 Å²	2	66 Å²	66	2%	0.021	34%	0.344	C	S	.	.	H	α-helix	trans	-61.3	-20.1	178.7	0	0	0	0	0	113.4	V439 Y463 V464 L465	V439-G461 WeakPolarHBondContact O-CA 3.49Å; G461-Y463 PolarHBondContact O-N 2.91Å; G461-V464 PolarHBondContact O-N 3.4Å; G461-L465 WeakPolarHBondContact O-CB 3.1Å; G461-L465 VanDerWaalsContact O-CG 3.26Å; G461-L465 WeakPolarHBondContact O-CG 3.3Å; G461-L465 PolarHBondContact O-N 3.47Å
462	Y	96	Very high	89.1	Confident	0 Å²	0	66.4 Å²	66.4	0%	0	34%	0.344	C	S	.	.	H	α-helix	trans	-56	-49.2	170.9	169.2	-108.2	0	0	0	112.1	I297 T298 K301 I361 E460 V464 L465 I466	I297-Y462 HydrophobicContact CB-CD2 3.84Å; I297-Y462 HydrophobicContact CB-CE2 4.19Å; I297-Y462 HydrophobicContact CG2-CD2 3.55Å; I297-Y462 HydrophobicContact CG2-CE2 4.26Å; I297-Y462 HydrophobicContact CG2-CG 4.29Å; T298-Y462 PolarHBondContact OG1-OH 2.69Å; K301-Y462 HydrophobicContact CD-CG 4.43Å; K301-Y462 HydrophobicContact CG-CD1 4.29Å; K301-Y462 HydrophobicContact CG-CD2 4.22Å; K301-Y462 HydrophobicContact CG-CG 4.03Å; I361-Y462 HydrophobicContact CB-CE1 4.04Å; I361-Y462 HydrophobicContact CG1-CE1 3.9Å; I361-Y462 HydrophobicContact CG2-CD1 4.45Å; I361-Y462 HydrophobicContact CG2-CE1 4.1Å; E460-Y462 PolarHBondContact O-N 3.04Å; Y462-V464 PolarHBondContact O-N 3.01Å; Y462-L465 PolarHBondContact O-N 3.04Å; Y462-I466 HydrophobicContact CD2-CG1 4.18Å; Y462-I466 HydrophobicContact CE1-CG1 4.26Å; Y462-I466 HydrophobicContact CE2-CD1 3.92Å; Y462-I466 HydrophobicContact CE2-CG1 3.72Å; Y462-I466 WeakPolarHBondContact O-CG1 3.45Å; Y462-I466 PolarHBondContact O-N 2.95Å
463	Y	96.9	Very high	90.8	Very high	42 Å²	42	61.8 Å²	61.8	17%	0.165	31%	0.314	C	S	.	.	H	α-helix	trans	-63.9	-44.4	179.3	-63.6	-71.6	0	0	0	111	A358 W362 E460 G461 L465 I466 F467	A358-Y463 HydrophobicContact CB-CD1 4Å; A358-Y463 HydrophobicContact CB-CE1 4.25Å; A358-Y463 WeakPolarHBondContact O-CE1 3.16Å; W362-Y463 VanDerWaalsContact CA-OH 3.26Å; W362-Y463 WeakPolarHBondContact CA-OH 3.05Å; W362-Y463 HydrophobicContact CB-CE1 4.11Å; W362-Y463 WeakPolarHBondContact CB-OH 3.47Å; W362-Y463 PolarHBondContact N-OH 3.41Å; E460-Y463 HydrophobicContact CB-CD2 3.85Å; E460-Y463 HydrophobicContact CB-CE2 4.11Å; E460-Y463 HydrophobicContact CG-CD2 4.48Å; E460-Y463 HydrophobicContact CG-CE2 4.31Å; E460-Y463 PolarHBondContact O-N 3.25Å; G461-Y463 PolarHBondContact O-N 2.91Å; Y463-L465 VanDerWaalsContact C-N 3.32Å; Y463-L465 PolarHBondContact O-N 3.03Å; Y463-I466 PolarHBondContact O-N 2.92Å; Y463-F467 WeakPolarHBondContact O-CD2 3.39Å; Y463-F467 PolarHBondContact O-N 3.29Å
464	V	96.1	Very high	92.1	Very high	44 Å²	44	60 Å²	60	27%	0.267	29%	0.293	S	S	.	.	H	α-helix	trans	-55.8	-48.4	176.5	-178.9	0	0	0	0	110.7	M442 V459 G461 Y462 I466 F467 L468	M442-V464 HydrophobicContact CB-CB 4.49Å; M442-V464 HydrophobicContact CB-CG1 4.47Å; V459-V464 HydrophobicContact CG1-CG2 3.8Å; G461-V464 PolarHBondContact O-N 3.4Å; Y462-V464 PolarHBondContact O-N 3.01Å; V464-I466 PolarHBondContact O-N 2.86Å; V464-F467 PolarHBondContact O-N 3.22Å; V464-L468 HydrophobicContact CG1-CD1 3.9Å; V464-L468 HydrophobicContact CG1-CG 4.34Å; V464-L468 WeakPolarHBondContact O-CB 3.28Å; V464-L468 VanDerWaalsContact O-CG 3.29Å; V464-L468 WeakPolarHBondContact O-CG 3.3Å; V464-L468 PolarHBondContact O-N 2.87Å
465	L	96.8	Very high	93.3	Very high	25 Å²	25	55.2 Å²	55.2	13%	0.131	28%	0.281	C	S	.	.	H	α-helix	trans	-65.1	-37.1	179	-71	174.5	0	0	0	112.9	A293 I297 A435 V439 M442 G461 Y462 Y463 G469	A293-L465 HydrophobicContact CB-CB 3.77Å; I297-L465 HydrophobicContact CD1-CD1 3.84Å; A435-L465 HydrophobicContact CB-CD1 4.32Å; A435-L465 WeakPolarHBondContact O-CD1 3.13Å; V439-L465 HydrophobicContact CB-CD1 3.99Å; V439-L465 HydrophobicContact CG2-CD1 4.17Å; M442-L465 HydrophobicContact CG-CD2 4.08Å; M442-L465 HydrophobicContact CG-CG 4.35Å; G461-L465 WeakPolarHBondContact O-CB 3.1Å; G461-L465 VanDerWaalsContact O-CG 3.26Å; G461-L465 WeakPolarHBondContact O-CG 3.3Å; G461-L465 PolarHBondContact O-N 3.47Å; Y462-L465 PolarHBondContact O-N 3.04Å; Y463-L465 VanDerWaalsContact C-N 3.32Å; Y463-L465 PolarHBondContact O-N 3.03Å; L465-G469 PolarHBondContact O-N 2.96Å
466	I	97.6	Very high	94.3	Very high	2 Å²	2	53.6 Å²	53.6	1%	0.01	27%	0.268	C	S	.	.	H	α-helix	trans	-63.3	-49	174.1	-69.9	-73	0	0	0	110.6	A293 A294 S354 L355 A358 Y462 Y463 V464 G469 V470	A293-I466 HydrophobicContact CB-CD1 3.77Å; A293-I466 HydrophobicContact CB-CG1 4.06Å; A294-I466 HydrophobicContact CB-CD1 3.94Å; S354-I466 WeakPolarHBondContact O-CG2 3.2Å; L355-I466 HydrophobicContact CD2-CG2 4.07Å; A358-I466 HydrophobicContact CB-CB 4.42Å; A358-I466 HydrophobicContact CB-CG2 3.89Å; Y462-I466 HydrophobicContact CD2-CG1 4.18Å; Y462-I466 HydrophobicContact CE1-CG1 4.26Å; Y462-I466 HydrophobicContact CE2-CD1 3.92Å; Y462-I466 HydrophobicContact CE2-CG1 3.72Å; Y462-I466 WeakPolarHBondContact O-CG1 3.45Å; Y462-I466 PolarHBondContact O-N 2.95Å; Y463-I466 PolarHBondContact O-N 2.92Å; V464-I466 PolarHBondContact O-N 2.86Å; I466-G469 PolarHBondContact O-N 3.12Å; I466-V470 VanDerWaalsContact O-CG2 3.3Å; I466-V470 WeakPolarHBondContact O-CG2 3.49Å; I466-V470 PolarHBondContact O-N 2.8Å
467	F	97.2	Very high	95	Very high	117 Å²	117	48 Å²	48	51%	0.513	24%	0.243	S	C	.	.	H	α-helix	trans	-63.3	-44.1	179.6	-76.4	-68.5	0	0	0	112	L355 Y463 V464 V470 I471	L355-F467 HydrophobicContact CD2-CD1 3.8Å; L355-F467 HydrophobicContact CD2-CE1 3.69Å; L355-F467 HydrophobicContact CD2-CZ 4.47Å; Y463-F467 WeakPolarHBondContact O-CD2 3.39Å; Y463-F467 PolarHBondContact O-N 3.29Å; V464-F467 PolarHBondContact O-N 3.22Å; F467-V470 PolarHBondContact O-N 3.31Å; F467-I471 WeakPolarHBondContact O-CG1 3.35Å; F467-I471 PolarHBondContact O-N 3.31Å; F467-I471 VanDerWaalsContact O-N 3.11Å
468	L	96.6	Very high	95.7	Very high	79 Å²	79	51 Å²	51	41%	0.414	25%	0.25	S	S	.	.	H	α-helix	trans	-61.4	-44.8	174	-71.7	176.3	0	0	0	111.6	V464 V470 I471 I472	V464-L468 HydrophobicContact CG1-CD1 3.9Å; V464-L468 HydrophobicContact CG1-CG 4.34Å; V464-L468 WeakPolarHBondContact O-CB 3.28Å; V464-L468 VanDerWaalsContact O-CG 3.29Å; V464-L468 WeakPolarHBondContact O-CG 3.3Å; V464-L468 PolarHBondContact O-N 2.87Å; L468-V470 VanDerWaalsContact C-N 3.29Å; L468-V470 PolarHBondContact O-N 3.27Å; L468-I471 PolarHBondContact O-N 2.76Å; L468-I472 WeakPolarHBondContact O-CB 3.28Å; L468-I472 VanDerWaalsContact O-CG1 3.26Å; L468-I472 WeakPolarHBondContact O-CG1 3.12Å; L468-I472 PolarHBondContact O-N 3.12Å
469	G	97.5	Very high	96.3	Very high	5 Å²	5	50.1 Å²	50.1	5%	0.052	25%	0.249	C	C	.	.	H	α-helix	trans	-56.9	-43.4	176.4	0	0	0	0	0	112	A290 L465 I466 I472 G473	A290-G469 VanDerWaalsContact CA-O 3.29Å; A290-G469 WeakPolarHBondContact CA-O 3.17Å; A290-G469 VanDerWaalsContact CB-O 3.26Å; A290-G469 WeakPolarHBondContact CB-O 3.5Å; L465-G469 PolarHBondContact O-N 2.96Å; I466-G469 PolarHBondContact O-N 3.12Å; G469-I472 PolarHBondContact O-N 2.87Å; G469-G473 PolarHBondContact O-N 2.69Å
470	V	98	Very high	96.7	Very high	13 Å²	13	48 Å²	48	8%	0.079	24%	0.238	C	C	.	.	H	α-helix	trans	-62.6	-45.2	177.3	167.5	0	0	0	0	112.4	N351 M352 L355 I466 F467 L468 G473 W474	N351-V470 PolarHBondContact ND2-O 2.8Å; N351-V470 WeakPolarHBondContact OD1-CA 3.29Å; M352-V470 HydrophobicContact CE-CB 4.5Å; M352-V470 HydrophobicContact CE-CG1 3.34Å; M352-V470 HydrophobicContact CE-CG2 4.46Å; L355-V470 HydrophobicContact CD1-CG1 4.38Å; L355-V470 HydrophobicContact CD2-CG2 3.87Å; L355-V470 HydrophobicContact CG-CG2 3.85Å; I466-V470 VanDerWaalsContact O-CG2 3.3Å; I466-V470 WeakPolarHBondContact O-CG2 3.49Å; I466-V470 PolarHBondContact O-N 2.8Å; F467-V470 PolarHBondContact O-N 3.31Å; L468-V470 VanDerWaalsContact C-N 3.29Å; L468-V470 PolarHBondContact O-N 3.27Å; V470-G473 PolarHBondContact O-N 2.84Å; V470-W474 VanDerWaalsContact O-CD1 3.25Å; V470-W474 PolarHBondContact O-N 3.27Å; V470-W474 VanDerWaalsContact O-N 3.12Å
471	I	98	Very high	96.9	Very high	97 Å²	97	44.8 Å²	44.8	50%	0.497	22%	0.223	S	C	.	.	H	α-helix	trans	-61.9	-48.7	176.4	-66.6	166.6	0	0	0	110.1	F467 L468 G473 W474 I475	F467-I471 WeakPolarHBondContact O-CG1 3.35Å; F467-I471 PolarHBondContact O-N 3.31Å; F467-I471 VanDerWaalsContact O-N 3.11Å; L468-I471 PolarHBondContact O-N 2.76Å; I471-G473 VanDerWaalsContact C-N 3.27Å; I471-G473 PolarHBondContact O-N 3.38Å; I471-W474 PolarHBondContact O-N 3.16Å; I471-I475 HydrophobicContact CG2-CD1 3.89Å; I471-I475 WeakPolarHBondContact O-CG1 3.48Å; I471-I475 PolarHBondContact O-N 3.11Å
472	I	97.7	Very high	97	Very high	66 Å²	66	51.3 Å²	51.3	34%	0.338	25%	0.251	S	S	.	.	H	α-helix	trans	-58.4	-41.5	176.9	-69.4	166.6	0	0	0	110.6	I289 L468 G469 W474 I475 W476	I289-I472 HydrophobicContact CB-CG2 4.32Å; I289-I472 HydrophobicContact CG2-CD1 4.15Å; I289-I472 HydrophobicContact CG2-CG2 4.02Å; L468-I472 WeakPolarHBondContact O-CB 3.28Å; L468-I472 VanDerWaalsContact O-CG1 3.26Å; L468-I472 WeakPolarHBondContact O-CG1 3.12Å; L468-I472 PolarHBondContact O-N 3.12Å; G469-I472 PolarHBondContact O-N 2.87Å; I472-W474 PolarHBondContact O-N 3.2Å; I472-I475 PolarHBondContact O-N 2.82Å; I472-W476 VanDerWaalsContact O-CB 3.26Å; I472-W476 WeakPolarHBondContact O-CB 3.35Å; I472-W476 PolarHBondContact O-N 3.44Å
473	G	97.8	Very high	97	Very high	0 Å²	0	54.3 Å²	54.3	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-60.8	-42.7	178.1	0	0	0	0	0	112.8	A290 Y347 G469 V470 I471 W476 L477	A290-G473 VanDerWaalsContact CB-CA 3.5Å; Y347-G473 WeakPolarHBondContact CE1-O 3.42Å; G469-G473 PolarHBondContact O-N 2.69Å; V470-G473 PolarHBondContact O-N 2.84Å; I471-G473 VanDerWaalsContact C-N 3.27Å; I471-G473 PolarHBondContact O-N 3.38Å; G473-W476 PolarHBondContact O-N 3.5Å; G473-L477 WeakPolarHBondContact O-CB 3.29Å; G473-L477 PolarHBondContact O-N 3.34Å
474	W	98.1	Very high	97	Very high	94 Å²	94	52.3 Å²	52.3	36%	0.356	26%	0.261	S	S	.	.	H	α-helix	trans	-65.4	-46.2	174.7	-77.5	114.7	0	0	0	112	P348 M352 V470 I471 I472 W476 L477 F478	P348-W474 HydrophobicContact CB-CH2 3.81Å; P348-W474 HydrophobicContact CB-CZ2 4.44Å; P348-W474 HydrophobicContact CB-CZ3 4.23Å; M352-W474 HydrophobicContact CE-CZ2 4.11Å; M352-W474 HydrophobicContact CG-CZ2 4.45Å; M352-W474 HydrophobicContact SD-CZ2 4.25Å; V470-W474 VanDerWaalsContact O-CD1 3.25Å; V470-W474 PolarHBondContact O-N 3.27Å; V470-W474 VanDerWaalsContact O-N 3.12Å; I471-W474 PolarHBondContact O-N 3.16Å; I472-W474 PolarHBondContact O-N 3.2Å; W474-W476 VanDerWaalsContact C-N 3.29Å; W474-W476 PolarHBondContact O-N 2.95Å; W474-L477 HydrophobicContact CE3-CD2 4.03Å; W474-L477 HydrophobicContact CZ3-CD2 3.87Å; W474-L477 PolarHBondContact O-N 3.31Å; W474-F478 HydrophobicContact CB-CE2 4.37Å; W474-F478 AromaticContact CE3-CE2 3.93Å; W474-F478 HydrophobicContact CE3-CE2 3.93Å; W474-F478 HydrophobicContact CE3-CZ 4.13Å; W474-F478 HydrophobicContact CZ3-CZ 4.49Å; W474-F478 WeakPolarHBondContact O-CD2 3.32Å; W474-F478 PolarHBondContact O-N 3.12Å; W474-F478 VanDerWaalsContact O-N 3.09Å
475	I	97.8	Very high	97	Very high	97 Å²	97	56.6 Å²	56.6	50%	0.497	27%	0.272	S	S	.	.	H	α-helix	trans	-57.6	-45.3	176.1	-66	169.2	0	0	0	110.4	I471 I472 L477 F478 T479	I471-I475 HydrophobicContact CG2-CD1 3.89Å; I471-I475 WeakPolarHBondContact O-CG1 3.48Å; I471-I475 PolarHBondContact O-N 3.11Å; I472-I475 PolarHBondContact O-N 2.82Å; I475-L477 PolarHBondContact O-N 3.27Å; I475-F478 PolarHBondContact O-N 3.5Å; I475-T479 HydrophobicContact CG2-CG2 4.47Å; I475-T479 WeakPolarHBondContact O-CB 3.33Å; I475-T479 WeakPolarHBondContact O-CG2 3.29Å; I475-T479 PolarHBondContact O-N 3.02Å; I475-T479 PolarHBondContact O-OG1 3.31Å
476	W	98	Very high	96.9	Very high	12 Å²	12	64.3 Å²	64.3	5%	0.045	30%	0.3	C	S	.	.	H	α-helix	trans	-60.9	-45.2	178	-174.7	94.9	0	0	0	111.6	V283 T286 A287 Y343 L344 Y347 I472 G473 W474 F478 T479 A480 G481 M484	V283-W476 HydrophobicContact CG1-CH2 4.2Å; V283-W476 HydrophobicContact CG1-CZ2 3.64Å; T286-W476 PolarHBondContact OG1-NE1 3.27Å; A287-W476 VanDerWaalsContact CA-CE2 3.44Å; A287-W476 HydrophobicContact CB-CD2 4.48Å; A287-W476 HydrophobicContact CB-CH2 3.84Å; A287-W476 HydrophobicContact CB-CZ2 3.27Å; Y343-W476 AromaticContact CE1-CH2 3.83Å; Y343-W476 HydrophobicContact CE1-CH2 3.83Å; Y343-W476 HydrophobicContact CE1-CZ3 4.12Å; L344-W476 HydrophobicContact CD2-CZ3 4.42Å; Y347-W476 HydrophobicContact CD1-CE3 4.28Å; Y347-W476 HydrophobicContact CD1-CZ3 4.42Å; Y347-W476 HydrophobicContact CD2-CE3 4.27Å; Y347-W476 AromaticContact CD2-CZ3 3.85Å; Y347-W476 HydrophobicContact CD2-CZ3 3.85Å; Y347-W476 AromaticContact CE1-CE3 3.72Å; Y347-W476 HydrophobicContact CE1-CE3 3.72Å; Y347-W476 HydrophobicContact CE1-CZ3 4.23Å; Y347-W476 HydrophobicContact CE2-CD2 4.44Å; Y347-W476 AromaticContact CE2-CE3 3.69Å; Y347-W476 HydrophobicContact CE2-CE3 3.69Å; Y347-W476 HydrophobicContact CE2-CH2 4.29Å; Y347-W476 AromaticContact CE2-CZ3 3.61Å; Y347-W476 HydrophobicContact CE2-CZ3 3.61Å; Y347-W476 HydrophobicContact CG-CZ3 4.23Å; Y347-W476 AromaticContact CZ-CE3 3.38Å; Y347-W476 AromaticContact CZ-CZ3 3.82Å; I472-W476 VanDerWaalsContact O-CB 3.26Å; I472-W476 WeakPolarHBondContact O-CB 3.35Å; I472-W476 PolarHBondContact O-N 3.44Å; G473-W476 PolarHBondContact O-N 3.5Å; W474-W476 VanDerWaalsContact C-N 3.29Å; W474-W476 PolarHBondContact O-N 2.95Å; W476-F478 VanDerWaalsContact C-N 3.3Å; W476-F478 PolarHBondContact O-N 3.1Å; W476-T479 CarbonylContact O-C 3.43Å; W476-T479 PolarHBondContact O-N 3.4Å; W476-T479 PolarHBondContact O-OG1 2.75Å; W476-A480 HydrophobicContact CD2-CB 3.87Å; W476-A480 VanDerWaalsContact CE2-CB 3.46Å; W476-A480 HydrophobicContact CG-CB 4Å; W476-A480 HydrophobicContact CZ2-CB 3.97Å; W476-A480 VanDerWaalsContact NE1-CB 3.34Å; W476-A480 WeakPolarHBondContact O-CA 3.23Å; W476-A480 PolarHBondContact O-N 2.83Å; W476-G481 PolarHBondContact O-N 3.45Å; W476-M484 HydrophobicContact CH2-CE 3.86Å
477	L	97.1	Very high	96.8	Very high	19 Å²	19	64.7 Å²	64.7	10%	0.099	30%	0.301	C	S	.	.	H	α-helix	trans	-61	-38.7	179	-174.7	62.9	0	0	0	112	L344 Y347 P348 G473 W474 I475 G481	L344-L477 HydrophobicContact CD2-CD1 3.99Å; Y347-L477 HydrophobicContact CD1-CB 4.21Å; Y347-L477 HydrophobicContact CD1-CD1 4.09Å; Y347-L477 HydrophobicContact CD1-CD2 4.49Å; Y347-L477 HydrophobicContact CD1-CG 4.5Å; Y347-L477 HydrophobicContact CE1-CB 4.36Å; Y347-L477 HydrophobicContact CG-CD1 4.42Å; P348-L477 HydrophobicContact CB-CD2 4.26Å; P348-L477 HydrophobicContact CG-CD2 4.46Å; G473-L477 WeakPolarHBondContact O-CB 3.29Å; G473-L477 PolarHBondContact O-N 3.34Å; W474-L477 HydrophobicContact CE3-CD2 4.03Å; W474-L477 HydrophobicContact CZ3-CD2 3.87Å; W474-L477 PolarHBondContact O-N 3.31Å; I475-L477 PolarHBondContact O-N 3.27Å; L477-G481 VanDerWaalsContact O-CA 3.31Å; L477-G481 WeakPolarHBondContact O-CA 2.85Å
478	F	96.2	Very high	96.7	Very high	129 Å²	129	60.1 Å²	60.1	57%	0.566	28%	0.282	S	S	*	.	H	α-helix	trans	-77.5	-24.7	178.2	-68	-59	0	0	0	114.1	W474 I475 W476 K482	W474-F478 HydrophobicContact CB-CE2 4.37Å; W474-F478 AromaticContact CE3-CE2 3.93Å; W474-F478 HydrophobicContact CE3-CE2 3.93Å; W474-F478 HydrophobicContact CE3-CZ 4.13Å; W474-F478 HydrophobicContact CZ3-CZ 4.49Å; W474-F478 WeakPolarHBondContact O-CD2 3.32Å; W474-F478 PolarHBondContact O-N 3.12Å; W474-F478 VanDerWaalsContact O-N 3.09Å; I475-F478 PolarHBondContact O-N 3.5Å; W476-F478 VanDerWaalsContact C-N 3.3Å; W476-F478 PolarHBondContact O-N 3.1Å; F478-K482 VanDerWaalsContact O-CD 3.3Å; F478-K482 WeakPolarHBondContact O-CD 3.24Å; F478-K482 WeakPolarHBondContact O-CE 3.04Å; F478-K482 WeakPolarHBondContact O-CG 3.2Å
479	T	95.7	Very high	96.6	Very high	82 Å²	82	60.6 Å²	60.6	50%	0.503	29%	0.288	S	S	.	.	T	Hydrogen-bonded Turn	trans	-100.5	-80.4	-178.2	55	0	0	0	0	111.2	I475 W476 G481 K482	I475-T479 HydrophobicContact CG2-CG2 4.47Å; I475-T479 WeakPolarHBondContact O-CB 3.33Å; I475-T479 WeakPolarHBondContact O-CG2 3.29Å; I475-T479 PolarHBondContact O-N 3.02Å; I475-T479 PolarHBondContact O-OG1 3.31Å; W476-T479 CarbonylContact O-C 3.43Å; W476-T479 PolarHBondContact O-N 3.4Å; W476-T479 PolarHBondContact O-OG1 2.75Å; T479-G481 PolarHBondContact O-N 2.83Å; T479-K482 WeakPolarHBondContact O-CB 3.33Å; T479-K482 PolarHBondContact O-N 3.37Å
480	A	95.9	Very high	96.4	Very high	15 Å²	15	62.4 Å²	62.4	12%	0.124	30%	0.298	C	S	.	.	H	α-helix	trans	-61.1	-28.8	178.9	0	0	0	0	0	113	V283 W476 K482 V483 M484	V283-A480 HydrophobicContact CG2-CB 4.44Å; W476-A480 HydrophobicContact CD2-CB 3.87Å; W476-A480 VanDerWaalsContact CE2-CB 3.46Å; W476-A480 HydrophobicContact CG-CB 4Å; W476-A480 HydrophobicContact CZ2-CB 3.97Å; W476-A480 VanDerWaalsContact NE1-CB 3.34Å; W476-A480 WeakPolarHBondContact O-CA 3.23Å; W476-A480 PolarHBondContact O-N 2.83Å; A480-K482 VanDerWaalsContact C-N 3.26Å; A480-K482 PolarHBondContact O-N 3.15Å; A480-V483 WeakPolarHBondContact O-CB 3.45Å; A480-V483 PolarHBondContact O-N 3.3Å; A480-V483 VanDerWaalsContact O-N 3.09Å; A480-M484 PolarHBondContact O-N 3.28Å
481	G	95.9	Very high	96	Very high	0 Å²	0	66.4 Å²	66.4	0%	0	32%	0.319	C	S	.	.	H	α-helix	trans	-60.2	-32.9	173.1	0	0	0	0	0	113.5	W476 L477 T479 M484 R485	W476-G481 PolarHBondContact O-N 3.45Å; L477-G481 VanDerWaalsContact O-CA 3.31Å; L477-G481 WeakPolarHBondContact O-CA 2.85Å; T479-G481 PolarHBondContact O-N 2.83Å; G481-M484 PolarHBondContact O-N 3.25Å; G481-R485 WeakPolarHBondContact O-CG 3.33Å; G481-R485 PolarHBondContact O-N 3.43Å; G481-R485 VanDerWaalsContact O-N 3.07Å
482	K	95.6	Very high	95.4	Very high	140 Å²	140	66 Å²	66	61%	0.609	31%	0.311	S	S	*	.	H	α-helix	trans	-69	-40.5	172.9	-66.1	176.6	-178.1	170.2	0	111.6	F478 T479 A480 M484 R485 R486	F478-K482 VanDerWaalsContact O-CD 3.3Å; F478-K482 WeakPolarHBondContact O-CD 3.24Å; F478-K482 WeakPolarHBondContact O-CE 3.04Å; F478-K482 WeakPolarHBondContact O-CG 3.2Å; T479-K482 WeakPolarHBondContact O-CB 3.33Å; T479-K482 PolarHBondContact O-N 3.37Å; A480-K482 VanDerWaalsContact C-N 3.26Å; A480-K482 PolarHBondContact O-N 3.15Å; K482-M484 VanDerWaalsContact C-N 3.32Å; K482-R485 PolarHBondContact O-N 3.46Å; K482-R486 PolarHBondContact O-N 2.95Å; K482-R486 VanDerWaalsContact O-N 3.07Å
483	V	96.5	Very high	94.8	Very high	62 Å²	62	66.3 Å²	66.3	38%	0.376	32%	0.316	S	S	.	.	H	α-helix	trans	-60.6	-46	174.8	-178.6	0	0	0	0	109.6	A279 V283 A480 R485 R486 L487	A279-V483 HydrophobicContact CB-CG1 4.32Å; V283-V483 HydrophobicContact CG2-CB 4.2Å; V283-V483 HydrophobicContact CG2-CG1 3.98Å; A480-V483 WeakPolarHBondContact O-CB 3.45Å; A480-V483 PolarHBondContact O-N 3.3Å; A480-V483 VanDerWaalsContact O-N 3.09Å; V483-R485 PolarHBondContact O-N 3.28Å; V483-R486 WeakPolarHBondContact O-CB 3.37Å; V483-R486 PolarHBondContact O-N 3.41Å; V483-R486 VanDerWaalsContact O-N 3.08Å; V483-L487 HydrophobicContact CG1-CD1 4.28Å; V483-L487 HydrophobicContact CG1-CG 4.42Å; V483-L487 WeakPolarHBondContact O-CG 3.43Å; V483-L487 PolarHBondContact O-N 2.99Å
484	M	96.1	Very high	94.4	Very high	0 Å²	0	69 Å²	69	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-60.6	-41.6	178.3	-170.1	130.9	90.6	0	0	112.7	V283 L340 Y343 L344 W476 A480 G481 K482 R486 L487	V283-M484 HydrophobicContact CG1-CB 4.32Å; V283-M484 HydrophobicContact CG1-SD 3.53Å; V283-M484 VanDerWaalsContact CG1-SD 3.53Å; L340-M484 HydrophobicContact CB-CE 4.43Å; L340-M484 HydrophobicContact CB-CG 3.9Å; L340-M484 HydrophobicContact CB-SD 4.36Å; L340-M484 HydrophobicContact CD1-CG 3.46Å; L340-M484 VanDerWaalsContact CD1-CG 3.46Å; L340-M484 HydrophobicContact CD1-SD 3.79Å; L340-M484 HydrophobicContact CD2-SD 4.28Å; L340-M484 HydrophobicContact CG-CG 4.21Å; L340-M484 HydrophobicContact CG-SD 4.37Å; Y343-M484 HydrophobicContact CD1-CE 3.06Å; Y343-M484 HydrophobicContact CD2-CE 3.87Å; Y343-M484 HydrophobicContact CE1-CE 3.34Å; Y343-M484 HydrophobicContact CE2-CE 4.06Å; Y343-M484 HydrophobicContact CG-CE 3.39Å; L344-M484 HydrophobicContact CD2-CB 4.43Å; L344-M484 HydrophobicContact CD2-CE 3.87Å; L344-M484 HydrophobicContact CG-CE 4.16Å; W476-M484 HydrophobicContact CH2-CE 3.86Å; A480-M484 PolarHBondContact O-N 3.28Å; G481-M484 PolarHBondContact O-N 3.25Å; K482-M484 VanDerWaalsContact C-N 3.32Å; M484-R486 VanDerWaalsContact C-N 3.32Å; M484-R486 PolarHBondContact O-N 3.45Å; M484-L487 PolarHBondContact O-N 3.33Å
485	R	96.1	Very high	94.1	Very high	134 Å²	134	64.7 Å²	64.7	51%	0.506	32%	0.319	S	S	.	.	H	α-helix	trans	-60.4	-42.1	173	-70.1	-179.9	-168.8	147	6.2	112.2	L344 G481 K482 V483 Q488	L344-R485 HydrophobicContact CD1-CG 3.32Å; G481-R485 WeakPolarHBondContact O-CG 3.33Å; G481-R485 PolarHBondContact O-N 3.43Å; G481-R485 VanDerWaalsContact O-N 3.07Å; K482-R485 PolarHBondContact O-N 3.46Å; V483-R485 PolarHBondContact O-N 3.28Å; R485-Q488 PolarHBondContact O-N 3.05Å
486	R	95.7	Very high	93.7	Very high	188 Å²	188	62.7 Å²	62.7	71%	0.709	31%	0.305	S	S	*	.	H	α-helix	trans	-65.4	-39.3	178.8	-173.3	178.5	-179.8	-179.9	1.4	111.9	K482 V483 M484 Q488 T489 V490	K482-R486 PolarHBondContact O-N 2.95Å; K482-R486 VanDerWaalsContact O-N 3.07Å; V483-R486 WeakPolarHBondContact O-CB 3.37Å; V483-R486 PolarHBondContact O-N 3.41Å; V483-R486 VanDerWaalsContact O-N 3.08Å; M484-R486 VanDerWaalsContact C-N 3.32Å; M484-R486 PolarHBondContact O-N 3.45Å; R486-Q488 PolarHBondContact O-N 3.31Å; R486-T489 PolarHBondContact O-N 3.38Å; R486-T489 PolarHBondContact O-OG1 2.88Å; R486-V490 PolarHBondContact O-N 3.25Å
487	L	96	Very high	92.6	Very high	9 Å²	9	62.7 Å²	62.7	5%	0.047	31%	0.307	C	S	.	.	H	α-helix	trans	-58.5	-32.6	179.1	-72.1	172.6	0	0	0	112.8	P276 A279 L280 V283 F403 V483 M484 T489 V490 W495	P276-L487 HydrophobicContact CB-CD2 4.06Å; A279-L487 HydrophobicContact CB-CD1 4.4Å; A279-L487 HydrophobicContact CB-CD2 4Å; L280-L487 HydrophobicContact CB-CD1 4.07Å; L280-L487 HydrophobicContact CD1-CD1 3.84Å; V283-L487 HydrophobicContact CG2-CD1 4.49Å; F403-L487 HydrophobicContact CZ-CB 4.34Å; V483-L487 HydrophobicContact CG1-CD1 4.28Å; V483-L487 HydrophobicContact CG1-CG 4.42Å; V483-L487 WeakPolarHBondContact O-CG 3.43Å; V483-L487 PolarHBondContact O-N 2.99Å; M484-L487 PolarHBondContact O-N 3.33Å; L487-T489 PolarHBondContact O-N 2.81Å; L487-V490 PolarHBondContact O-N 2.72Å; L487-W495 HydrophobicContact CB-CH2 4.47Å; L487-W495 HydrophobicContact CB-CZ2 4.21Å; L487-W495 HydrophobicContact CD2-CH2 4.05Å; L487-W495 HydrophobicContact CD2-CZ2 4.06Å
488	Q	94.3	Very high	91	Very high	22 Å²	22	68.3 Å²	68.3	10%	0.103	34%	0.336	C	S	.	.	T	Hydrogen-bonded Turn	trans	-70	-16.2	175.7	-58.7	-176.3	98.9	0	0	114.1	R338 P339 L340 D341 F403 R485 R486	R338-Q488 HydrophobicContact CG-CB 4.45Å; R338-Q488 PolarHBondContact O-OE1 2.85Å; P339-Q488 VanDerWaalsContact N-OE1 3.17Å; L340-Q488 VanDerWaalsContact CB-CD 3.48Å; L340-Q488 HydrophobicContact CB-CG 4.04Å; L340-Q488 HydrophobicContact CD1-CG 3.81Å; L340-Q488 HydrophobicContact CG-CG 4.09Å; D341-Q488 PolarHBondContact OD1-NE2 2.69Å; F403-Q488 HydrophobicContact CD2-CG 4.5Å; F403-Q488 HydrophobicContact CE2-CG 4.13Å; R485-Q488 PolarHBondContact O-N 3.05Å; R486-Q488 PolarHBondContact O-N 3.31Å
489	T	93.8	Very high	88.9	Confident	88 Å²	88	66.7 Å²	66.7	54%	0.54	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-98.5	-5.6	177.8	63.3	0	0	0	0	113.4	R486 L487	R486-T489 PolarHBondContact O-N 3.38Å; R486-T489 PolarHBondContact O-OG1 2.88Å; L487-T489 PolarHBondContact O-N 2.81Å
490	V	93.3	Very high	86.1	Confident	44 Å²	44	71.4 Å²	71.4	27%	0.267	35%	0.353	S	S	.	.	S	Bend	trans	-69.5	131.7	176.7	175.1	0	0	0	0	108.8	P276 R486 L487	P276-V490 HydrophobicContact CB-CG1 4.27Å; P276-V490 HydrophobicContact CG-CG1 4.46Å; R486-V490 PolarHBondContact O-N 3.25Å; L487-V490 PolarHBondContact O-N 2.72Å
491	D	89.8	Confident	83.1	Confident	97 Å²	97	74.7 Å²	74.7	52%	0.519	38%	0.381	S	S	.	.			trans	-60.4	144.1	179.2	-175.7	50.7	0	0	0	111.9	T493 S494	D491-T493 PolarHBondContact O-N 3.27Å; D491-T493 WeakPolarHBondContact OD2-CB 3.2Å; D491-T493 WeakPolarHBondContact OD2-CG2 3.48Å; D491-T493 PolarHBondContact OD2-N 2.75Å; D491-T493 PolarHBondContact OD2-OG1 3.42Å; D491-S494 WeakPolarHBondContact O-CB 3.5Å; D491-S494 PolarHBondContact O-N 3.33Å
492	R	86.5	Confident	80	Confident	88 Å²	88	81.4 Å²	81.4	33%	0.332	45%	0.45	S	S	.	.	G	3₁₀ helix	trans	-59.3	-33.9	-174.5	-73.3	-173.4	174.2	-176.4	-4.3	112.4	S494 W495	R492-S494 PolarHBondContact O-N 2.74Å; R492-W495 WeakPolarHBondContact O-CB 3.49Å; R492-W495 PolarHBondContact O-N 2.65Å
493	T	85	Confident	79.2	Confident	73 Å²	73	78.5 Å²	78.5	45%	0.448	44%	0.442	S	S	.	.	G	3₁₀ helix	trans	-62.9	-25.6	178.7	64.1	0	0	0	0	113.1	D491 W495 W496	D491-T493 PolarHBondContact O-N 3.27Å; D491-T493 WeakPolarHBondContact OD2-CB 3.2Å; D491-T493 WeakPolarHBondContact OD2-CG2 3.48Å; D491-T493 PolarHBondContact OD2-N 2.75Å; D491-T493 PolarHBondContact OD2-OG1 3.42Å; T493-W495 VanDerWaalsContact C-N 3.26Å; T493-W495 PolarHBondContact O-N 2.76Å; T493-W496 PolarHBondContact O-N 3.11Å
494	S	90.2	Very high	78.3	Confident	57 Å²	57	79.4 Å²	79.4	40%	0.399	45%	0.446	S	S	.	.	G	3₁₀ helix	trans	-75.8	-15.4	177.3	-61.3	0	0	0	0	113.3	P276 D491 R492	P276-S494 VanDerWaalsContact CG-O 3.3Å; P276-S494 WeakPolarHBondContact CG-O 3.08Å; D491-S494 WeakPolarHBondContact O-CB 3.5Å; D491-S494 PolarHBondContact O-N 3.33Å; R492-S494 PolarHBondContact O-N 2.74Å
495	W	91.5	Very high	77.3	Confident	2 Å²	2	83.8 Å²	83.8	1%	0.008	47%	0.47	C	S	.	.	G	3₁₀ helix	trans	-87.6	-14.1	174.7	-66.8	89.2	0	0	0	112.4	L274 P276 V277 L280 F403 V407 Y416 L487 R492 T493	L274-W495 WeakPolarHBondContact CD1-O 3.47Å; P276-W495 HydrophobicContact CB-CD2 3.99Å; P276-W495 HydrophobicContact CB-CE3 4.08Å; P276-W495 HydrophobicContact CB-CH2 3.78Å; P276-W495 HydrophobicContact CB-CZ2 3.67Å; P276-W495 HydrophobicContact CB-CZ3 3.98Å; P276-W495 HydrophobicContact CG-CD2 4.19Å; P276-W495 HydrophobicContact CG-CE3 4.34Å; V277-W495 HydrophobicContact CG2-CE3 3.93Å; V277-W495 HydrophobicContact CG2-CZ3 4.1Å; L280-W495 HydrophobicContact CB-CH2 4.2Å; L280-W495 HydrophobicContact CB-CZ3 4.32Å; L280-W495 HydrophobicContact CD2-CH2 4.03Å; L280-W495 HydrophobicContact CD2-CZ3 3.84Å; F403-W495 AromaticContact CE1-CH2 3.76Å; F403-W495 HydrophobicContact CE1-CH2 3.76Å; F403-W495 HydrophobicContact CE1-CZ2 4.05Å; F403-W495 HydrophobicContact CE1-CZ3 4.43Å; F403-W495 AromaticContact CZ-CH2 3.8Å; F403-W495 HydrophobicContact CZ-CH2 3.8Å; F403-W495 AromaticContact CZ-CZ2 3.59Å; F403-W495 HydrophobicContact CZ-CZ2 3.59Å; V407-W495 HydrophobicContact CB-CB 4.23Å; V407-W495 HydrophobicContact CB-CD2 3.72Å; V407-W495 HydrophobicContact CB-CE3 3.9Å; V407-W495 HydrophobicContact CB-CG 3.88Å; V407-W495 HydrophobicContact CG1-CD2 3.85Å; V407-W495 HydrophobicContact CG1-CE3 4.29Å; V407-W495 HydrophobicContact CG1-CG 4.14Å; V407-W495 HydrophobicContact CG1-CZ2 4.25Å; V407-W495 HydrophobicContact CG2-CD2 4.32Å; V407-W495 HydrophobicContact CG2-CE3 3.97Å; V407-W495 HydrophobicContact CG2-CZ3 4.29Å; Y416-W495 WeakPolarHBondContact CE2-O 3.49Å; Y416-W495 PolarHBondContact OH-O 3.46Å; L487-W495 HydrophobicContact CB-CH2 4.47Å; L487-W495 HydrophobicContact CB-CZ2 4.21Å; L487-W495 HydrophobicContact CD2-CH2 4.05Å; L487-W495 HydrophobicContact CD2-CZ2 4.06Å; R492-W495 WeakPolarHBondContact O-CB 3.49Å; R492-W495 PolarHBondContact O-N 2.65Å; T493-W495 VanDerWaalsContact C-N 3.26Å; T493-W495 PolarHBondContact O-N 2.76Å
496	W	87.7	Confident	76.2	Confident	55 Å²	55	80.8 Å²	80.8	21%	0.208	47%	0.468	C	S	.	.	S	Bend	trans	-102.2	139	-178.3	-56.2	-15.4	0	0	0	109.2	V407 D409 T493 L498	V407-W496 PolarHBondContact O-NE1 3.31Å; V407-W496 VanDerWaalsContact O-NE1 3.09Å; D409-W496 HydrophobicContact CB-CB 4.48Å; D409-W496 HydrophobicContact CB-CD2 4.47Å; D409-W496 HydrophobicContact CB-CG 3.95Å; T493-W496 PolarHBondContact O-N 3.11Å; W496-L498 PolarHBondContact O-N 3.42Å
497	P	76.2	Confident	75	Confident	13 Å²	13	74.1 Å²	74.1	8%	0.084	45%	0.453	C	S	.	.			trans	-64	108.4	167.3	27.8	-29	0	0	0	105.9	R270 I271 T499	R270-P497 HydrophobicContact CB-CB 4.45Å; I271-P497 HydrophobicContact CD1-CG 4.39Å; I271-P497 HydrophobicContact CG1-CG 3.99Å; P497-T499 PolarHBondContact O-N 3.02Å
498	L	62.7	Low	73.6	Confident	137 Å²	137	78.5 Å²	78.5	72%	0.717	48%	0.48	S	S	*	.			trans	-49.1	110.2	171.9	-72.1	167	0	0	0	106.5	W496 Q500	W496-L498 PolarHBondContact O-N 3.42Å; L498-Q500 PolarHBondContact O-N 2.95Å
499	T	52.3	Low	72.1	Confident	95 Å²	95	82.5 Å²	82.5	58%	0.583	51%	0.507	S	S	*	.			trans	-62.1	93.1	161.7	35.1	0	0	0	0	103.7	P497 A501	P497-T499 PolarHBondContact O-N 3.02Å; T499-A501 PolarHBondContact O-N 2.86Å
500	Q	36.2	Very low	70.5	Confident	180 Å²	180	82.1 Å²	82.1	84%	0.841	51%	0.505	S	S	*	.			trans	-52.9	104.9	157.3	-78.6	-172.5	-22.3	0	0	103.9	L498 G502	L498-Q500 PolarHBondContact O-N 2.95Å; Q500-G502 PolarHBondContact O-N 3Å
501	A	33.1	Very low	68.6	Low	85 Å²	85	85.3 Å²	85.3	70%	0.702	53%	0.525	S	S	*	.			trans	-57.3	90.5	156.3	0	0	0	0	0	104.6	T499	T499-A501 PolarHBondContact O-N 2.86Å
502	G	31.5	Very low	66.6	Low	141 Å²	141	84.2 Å²	84.2	100%	1.454	53%	0.525	S	S	*	.			trans	-95.1	0	169.5	0	0	0	0	0	107.9	Q500	Q500-G502 PolarHBondContact O-N 3Å

Retrieved 502 of 502 residues in 1311.4 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).