A0A077ZGJ7_TRITR Loading...

Transmembrane serine protease 8

AlphaFold DB , UniProt , Accession A0A077ZGJ7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 655 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M48.7Very low79.9Confident244 Ų24469.2 Ų69.2100%1.20236%0.364SS*.  0145.40-72.7176.317100107.6S3M1-S3 PolarHBondContact O-N 2.97Å
2D61.9Low79.6Confident77 Ų7769.1 Ų69.141%0.41237%0.37SS..  trans-57.3129.5169.4-76.94.5000109.2F4 R57D2-F4 PolarHBondContact O-N 2.59Å; D2-R57 IonicContact OD2-CZ 3Å; D2-R57 VanDerWaalsContact OD2-CZ 3.23Å; D2-R57 IonicContact OD2-NH1 3.95Å; D2-R57 PolarHBondContact OD2-NH1 3Å; D2-R57 IonicContact OD2-NH2 2.64Å; D2-R57 PolarHBondContact OD2-NH2 3.38Å
3S66.9Low79.1Confident93 Ų9366.2 Ų66.265%0.6536%0.355SS*.SBendtrans-66.6-26.2173.344.80000112.6M1M1-S3 PolarHBondContact O-N 2.97Å
4F76.4Confident77.8Confident60 Ų6063.6 Ų63.626%0.26335%0.346SS..SBendtrans-135.681.5-180-63.2-80.4000109.6D2 R57 Y135 V140D2-F4 PolarHBondContact O-N 2.59Å; F4-R57 PolarHBondContact O-NH1 3.11Å; F4-R57 VanDerWaalsContact O-NH1 3.16Å; F4-Y135 HydrophobicContact CB-CD2 3.61Å; F4-Y135 HydrophobicContact CB-CG 4.06Å; F4-Y135 HydrophobicContact CD2-CD2 4.43Å; F4-Y135 HydrophobicContact CG-CD2 4.24Å; F4-Y135 HydrophobicContact CG-CG 4.34Å; F4-V140 HydrophobicContact CD1-CG2 4.4Å
5P87.3Confident76.2Confident33 Ų3372.5 Ų72.521%0.21439%0.385CS..  trans-65146172.528.8-35.6000110.8L8 V140P5-L8 HydrophobicContact CB-CD1 3.89Å; P5-L8 HydrophobicContact CG-CB 4.23Å; P5-L8 HydrophobicContact CG-CD1 3.44Å; P5-L8 VanDerWaalsContact CG-CD1 3.44Å; P5-L8 HydrophobicContact CG-CG 4.45Å; P5-V140 WeakPolarHBondContact O-CG1 3.46Å
6C93.1Very high74.5Confident15 Ų1569 Ų6910%0.10137%0.372CS..THydrogen-bonded Turntrans-62.4156.6176.762.50000112.4L8 P141 C143C6-L8 PolarHBondContact O-N 2.76Å; C6-P141 CarbonylContact C-O 3.52Å; C6-P141 VanDerWaalsContact CA-O 3.28Å; C6-P141 WeakPolarHBondContact CA-O 3.27Å; C6-P141 HydrophobicContact CB-CG 4.38Å; C6-P141 WeakPolarHBondContact CB-O 3.47Å; C6-C143 HydrophobicContact CB-CB 4.02Å; C6-C143 WeakPolarHBondContact CB-SG 3.33Å; C6-C143 PolarHBondContact O-SG 2.91Å; C6-C143 WeakPolarHBondContact SG-CA 3.39Å; C6-C143 WeakPolarHBondContact SG-CB 3.45Å; C6-C143 CovalentContact SG-SG 2.05Å; C6-C143 PolarHBondContact SG-SG 2.77Å
7G93Very high72.4Confident0 Ų072 Ų720%040%0.396CS..THydrogen-bonded Turntrans65.319.417100000114.4P141 R253 F254G7-P141 PolarHBondContact N-O 3.47Å; G7-R253 CarbonylContact O-C 3.57Å; G7-R253 WeakPolarHBondContact O-CA 3.35Å; G7-F254 VanDerWaalsContact CA-O 3.3Å; G7-F254 WeakPolarHBondContact CA-O 3.5Å; G7-F254 WeakPolarHBondContact O-CD2 3.44Å; G7-F254 PolarHBondContact O-N 3.06Å
8L92Very high70.2Confident70 Ų7073.4 Ų73.437%0.36640%0.403SS..  trans-124.393.8-177.7-86163.5000109.5P5 C6 G252 R253P5-L8 HydrophobicContact CB-CD1 3.89Å; P5-L8 HydrophobicContact CG-CB 4.23Å; P5-L8 HydrophobicContact CG-CD1 3.44Å; P5-L8 VanDerWaalsContact CG-CD1 3.44Å; P5-L8 HydrophobicContact CG-CG 4.45Å; C6-L8 PolarHBondContact O-N 2.76Å; L8-G252 WeakPolarHBondContact CD2-O 3.4Å; L8-R253 HydrophobicContact CD1-CG 4.03Å; L8-R253 HydrophobicContact CG-CG 4.06Å
9P90.5Very high68Low26 Ų2679.9 Ų79.917%0.16942%0.42CS..  trans-75.3143176.133.9-34.5000110.2F11 S30 P32 W33 F254P9-F11 WeakPolarHBondContact CB-O 3.49Å; P9-S30 WeakPolarHBondContact CB-O 3.48Å; P9-P32 HydrophobicContact CB-CG 3.86Å; P9-W33 HydrophobicContact CB-CH2 4.33Å; P9-W33 HydrophobicContact CB-CZ3 4.25Å; P9-W33 HydrophobicContact CG-CH2 4.07Å; P9-W33 HydrophobicContact CG-CZ3 4.32Å; P9-F254 HydrophobicContact CG-CD2 4.36Å; P9-F254 HydrophobicContact CG-CE2 4.21Å
10K86.2Confident66.1Low121 Ų12178.3 Ų78.353%0.52641%0.411SS..SBendtrans-69.6-38.6172-179.5173-179.1174.40111.6D137K10-D137 HydrophobicContact CD-CB 3.72Å; K10-D137 WeakPolarHBondContact CD-OD1 3.14Å; K10-D137 IonicContact NZ-OD1 3.09Å; K10-D137 PolarHBondContact NZ-OD1 2.81Å; K10-D137 IonicContact NZ-OD2 3.66Å; K10-D137 PolarHBondContact NZ-OD2 2.87Å
11F83.5Confident64.7Low22 Ų2276.3 Ų76.310%0.09641%0.411CS..SBendtrans-88.9127.6178.1-57.4-88000109.1P9 H29 S30 D137 Y138 I642P9-F11 WeakPolarHBondContact CB-O 3.49Å; F11-H29 HydrophobicContact CB-CB 4.48Å; F11-H29 HydrophobicContact CD2-CB 3.42Å; F11-H29 VanDerWaalsContact CD2-CB 3.42Å; F11-H29 HydrophobicContact CE2-CB 3.81Å; F11-H29 HydrophobicContact CG-CB 4Å; F11-S30 WeakPolarHBondContact O-CA 3.36Å; F11-D137 HydrophobicContact CE2-CB 4.09Å; F11-Y138 AromaticContact CE2-CD1 3.64Å; F11-Y138 HydrophobicContact CE2-CD1 3.64Å; F11-Y138 AromaticContact CE2-CE1 3.55Å; F11-Y138 HydrophobicContact CE2-CE1 3.55Å; F11-Y138 HydrophobicContact CZ-CD1 4.19Å; F11-Y138 AromaticContact CZ-CE1 3.61Å; F11-Y138 HydrophobicContact CZ-CE1 3.61Å; F11-I642 HydrophobicContact CE1-CD1 4.08Å
12P75.8Confident64.8Low68 Ų6868.6 Ų68.644%0.44238%0.38SS..PPolyproline II helixtrans-67.9150.9178.731.8-36.1000110.2A14 S30 L639P12-A14 PolarHBondContact O-N 3.34Å; P12-S30 VanDerWaalsContact O-CB 3.23Å; P12-S30 WeakPolarHBondContact O-CB 3.39Å; P12-L639 VanDerWaalsContact CD-CD2 3.42Å; P12-L639 HydrophobicContact CG-CD1 3.6Å; P12-L639 HydrophobicContact CG-CD2 3.77Å; P12-L639 HydrophobicContact CG-CG 4.29Å
13L73.6Confident64.5Low32 Ų3266.1 Ų66.117%0.16837%0.373CS..PPolyproline II helixtrans-58.4137.7171.7-62.3-176.6000110.9Q15 S30 L31 Y158 M195 F254L13-Q15 PolarHBondContact O-N 2.66Å; L13-S30 WeakPolarHBondContact CD2-O 3.37Å; L13-L31 HydrophobicContact CD2-CD2 3.71Å; L13-L31 HydrophobicContact CD2-CG 4.21Å; L13-Y158 HydrophobicContact CD1-CD2 4.21Å; L13-Y158 HydrophobicContact CD1-CE2 3.98Å; L13-M195 HydrophobicContact CD1-CE 3.53Å; L13-M195 HydrophobicContact CD1-SD 4.42Å; L13-M195 HydrophobicContact CD2-CE 3.66Å; L13-M195 HydrophobicContact CD2-SD 3.9Å; L13-M195 HydrophobicContact CG-CE 4.17Å; L13-F254 HydrophobicContact CD1-CE1 3.63Å; L13-F254 HydrophobicContact CD1-CE2 4.34Å; L13-F254 HydrophobicContact CD1-CZ 3.36Å; L13-F254 HydrophobicContact CG-CZ 3.96Å
14A60.4Low64.4Low29 Ų2963.6 Ų63.624%0.2435%0.349CS..PPolyproline II helixtrans-56.6124.8166.300000109.6P12 G16 W24 A27P12-A14 PolarHBondContact O-N 3.34Å; A14-G16 PolarHBondContact O-N 3.39Å; A14-W24 PolarHBondContact O-NE1 3.15Å; A14-A27 HydrophobicContact CB-CB 3.76Å
15Q53.2Low64.4Low197 Ų19764.7 Ų64.792%0.92136%0.355SS*.  trans-85.887.6170.1-64.4-172.219.300108.7L13L13-Q15 PolarHBondContact O-N 2.66Å
16G48.9Very low63.8Low17 Ų1763.2 Ų63.218%0.17535%0.346CS..  trans-67.8152.5174.100000112.4A14 N18A14-G16 PolarHBondContact O-N 3.39Å; G16-N18 PolarHBondContact O-N 2.61Å
17P39.4Very low63.1Low120 Ų12063.5 Ų63.578%0.77935%0.349SS*.  trans-67.199.1173.227.4-33.2000110.1R19P17-R19 PolarHBondContact O-N 3.39Å
18N32.1Very low62.6Low98 Ų9867.7 Ų67.752%0.52437%0.368SS..THydrogen-bonded Turntrans-7262.6-172.6-133.958.2000112.7G16 W24 D197G16-N18 PolarHBondContact O-N 2.61Å; N18-W24 WeakPolarHBondContact OD1-CZ3 3.21Å; N18-D197 PolarHBondContact ND2-OD2 3.21Å; N18-D197 VanDerWaalsContact OD1-CG 3.26Å; N18-D197 PolarHBondContact OD1-OD1 3.36Å; N18-D197 VanDerWaalsContact OD1-OD1 3.14Å
19R28.5Very low62.1Low196 Ų19665.2 Ų65.274%0.7435%0.354SS*.THydrogen-bonded Turntrans-115.2-22.4-177.5-115.1-177.1-171.8-169.13.9115.1P17P17-R19 PolarHBondContact O-N 3.39Å
20I30.9Very low62Low47 Ų4764 Ų6424%0.24135%0.346CS..SBendtrans-156.2152174.91.9109.1000116.8S22 F521 L524I20-S22 PolarHBondContact O-N 3.29Å; I20-F521 HydrophobicContact CB-CE1 3.78Å; I20-F521 HydrophobicContact CB-CZ 3.82Å; I20-F521 HydrophobicContact CD1-CD1 3.68Å; I20-F521 HydrophobicContact CD1-CD2 3.81Å; I20-F521 HydrophobicContact CD1-CE1 3.76Å; I20-F521 HydrophobicContact CD1-CE2 3.86Å; I20-F521 HydrophobicContact CD1-CG 3.76Å; I20-F521 HydrophobicContact CD1-CZ 3.88Å; I20-F521 HydrophobicContact CG1-CD1 4.11Å; I20-F521 HydrophobicContact CG1-CD2 4.1Å; I20-F521 HydrophobicContact CG1-CE1 3.64Å; I20-F521 HydrophobicContact CG1-CE2 3.6Å; I20-F521 HydrophobicContact CG1-CG 4.37Å; I20-F521 HydrophobicContact CG1-CZ 3.4Å; I20-F521 HydrophobicContact CG2-CE1 3.42Å; I20-F521 VanDerWaalsContact CG2-CE1 3.42Å; I20-F521 HydrophobicContact CG2-CE2 4.29Å; I20-F521 HydrophobicContact CG2-CZ 3.28Å; I20-L524 HydrophobicContact CD1-CD1 4.24Å
21G36.4Very low62.2Low38 Ų3858.6 Ų58.639%0.39232%0.323SS..SBendtrans-7058.2-174.600000115.7
22S50.4Low62.7Low81 Ų8157.6 Ų57.657%0.56632%0.319SS*.SBendtrans-136.9114.8158.9-62.80000104.7I20I20-S22 PolarHBondContact O-N 3.29Å
23G57Low63.7Low26 Ų2654.4 Ų54.427%0.26830%0.298SS..PPolyproline II helixtrans-58.1164-17300000114M194 M195G23-M194 WeakPolarHBondContact O-CE 3.34Å; G23-M195 CarbonylContact C-O 3.6Å; G23-M195 WeakPolarHBondContact CA-O 3.4Å
24W64.7Low64.6Low39 Ų3953 Ų5315%0.14829%0.291CS..EExtended strand (participates in β ladder)trans-96.6160.1175.259.299.1000111.1A14 N18 A26 Y158 M194 M195 D197A14-W24 PolarHBondContact O-NE1 3.15Å; N18-W24 WeakPolarHBondContact OD1-CZ3 3.21Å; W24-A26 PolarHBondContact O-N 2.76Å; W24-Y158 HydrophobicContact CH2-CD1 4.2Å; W24-Y158 HydrophobicContact CH2-CE1 4.17Å; W24-Y158 HydrophobicContact CZ2-CD1 4.25Å; W24-Y158 HydrophobicContact CZ2-CE1 4.19Å; W24-M194 VanDerWaalsContact C-CE 3.41Å; W24-M194 CarbonylContact O-C 3.58Å; W24-M194 WeakPolarHBondContact O-CA 3.42Å; W24-M195 HydrophobicContact CZ2-CG 4.34Å; W24-M195 PolarHBondContact N-O 3.2Å; W24-M195 PolarHBondContact O-N 3.18Å; W24-D197 HydrophobicContact CH2-CB 3.93Å; W24-D197 VanDerWaalsContact CH2-N 3.29Å; W24-D197 HydrophobicContact CZ3-CB 4.3Å
25E74.8Confident66.3Low83 Ų8351.7 Ų51.739%0.38828%0.28SS..EExtended strand (participates in β ladder)trans-61.8127.6168.9-173.8-177.2151.200108.5H95 K192 M194E25-H95 IonicContact OE1-CD2 2.6Å; E25-H95 IonicContact OE1-CE1 3.88Å; E25-H95 IonicContact OE1-NE2 3.28Å; E25-H95 PolarHBondContact OE1-NE2 3.16Å; E25-K192 HydrophobicContact CG-CB 4.3Å; E25-K192 HydrophobicContact CG-CD 4.07Å; E25-K192 WeakPolarHBondContact OE1-CD 3.31Å; E25-K192 IonicContact OE1-NZ 3.69Å; E25-K192 PolarHBondContact OE1-NZ 3.06Å; E25-K192 VanDerWaalsContact OE2-CD 3.27Å; E25-K192 WeakPolarHBondContact OE2-CD 3.48Å; E25-K192 IonicContact OE2-NZ 3.56Å; E25-K192 PolarHBondContact OE2-NZ 3.22Å; E25-M194 HydrophobicContact CB-SD 4.34Å
26A76.5Confident68Low3 Ų342.8 Ų42.83%0.02524%0.238CC..PPolyproline II helixtrans-59.5150.9175.600000110.1W24 K28 L31 H95 L193 M195W24-A26 PolarHBondContact O-N 2.76Å; A26-K28 PolarHBondContact O-N 2.85Å; A26-L31 HydrophobicContact CB-CD1 3.87Å; A26-H95 PolarHBondContact O-CE1 2.94Å; A26-L193 HydrophobicContact CB-CB 4.35Å; A26-L193 HydrophobicContact CB-CD2 4.26Å; A26-L193 HydrophobicContact CB-CG 3.98Å; A26-L193 WeakPolarHBondContact CB-O 3.27Å; A26-L193 PolarHBondContact N-O 3.06Å; A26-M195 HydrophobicContact CB-CB 4.17Å
27A78.4Confident70Confident20 Ų2042 Ų4217%0.16523%0.23CC..PPolyproline II helixtrans-64.2134.2165.300000107.7A14 H29 S30A14-A27 HydrophobicContact CB-CB 3.76Å; A27-H29 PolarHBondContact O-N 2.96Å; A27-S30 PolarHBondContact N-OG 2.99Å; A27-S30 VanDerWaalsContact O-CB 3.25Å; A27-S30 WeakPolarHBondContact O-CB 3.38Å; A27-S30 PolarHBondContact O-N 3.11Å; A27-S30 PolarHBondContact O-OG 3.24Å
28K80.9Confident72.2Confident88 Ų8837.6 Ų37.638%0.38320%0.199SC..THydrogen-bonded Turntrans-48127.5176.8-162.1-173.9177.8-175.30109.7A26 S30 H95 E307A26-K28 PolarHBondContact O-N 2.85Å; K28-S30 PolarHBondContact O-N 3.1Å; K28-S30 VanDerWaalsContact O-N 3.08Å; K28-H95 HydrophobicContact CG-CB 4.07Å; K28-E307 WeakPolarHBondContact CE-OE1 3.03Å; K28-E307 WeakPolarHBondContact CE-OE2 3.27Å; K28-E307 IonicContact NZ-OE1 2.72Å; K28-E307 IonicContact NZ-OE2 2.82Å; K28-E307 PolarHBondContact NZ-OE2 2.94Å
29H83.2Confident74.5Confident18 Ų1833.1 Ų33.18%0.08318%0.175CC..THydrogen-bonded Turntrans61.34.1-175.6-46.4-54.9000118.2F11 A27 L31 P32 Y138 E307F11-H29 HydrophobicContact CB-CB 4.48Å; F11-H29 HydrophobicContact CD2-CB 3.42Å; F11-H29 VanDerWaalsContact CD2-CB 3.42Å; F11-H29 HydrophobicContact CE2-CB 3.81Å; F11-H29 HydrophobicContact CG-CB 4Å; A27-H29 PolarHBondContact O-N 2.96Å; H29-L31 PolarHBondContact O-N 3.27Å; H29-L31 VanDerWaalsContact O-N 3.16Å; H29-P32 WeakPolarHBondContact O-CD 3.16Å; H29-Y138 HydrophobicContact CB-CD1 3.84Å; H29-Y138 AromaticContact CD2-CD1 3.45Å; H29-Y138 VanDerWaalsContact CD2-CD1 3.45Å; H29-Y138 WeakPolarHBondContact CD2-CD1 3.29Å; H29-Y138 AromaticContact CD2-CE1 3.6Å; H29-Y138 AromaticContact CE1-CD1 3.92Å; H29-Y138 AromaticContact CG-CD1 3.33Å; H29-Y138 AromaticContact CG-CE1 3.99Å; H29-Y138 AromaticContact ND1-CD1 3.64Å; H29-Y138 AromaticContact NE2-CD1 3.84Å; H29-Y138 AromaticContact NE2-CE1 3.94Å; H29-E307 WeakPolarHBondContact CE1-CB 3.19Å; H29-E307 VanDerWaalsContact CE1-CG 3.46Å; H29-E307 WeakPolarHBondContact CE1-CG 3.35Å; H29-E307 IonicContact CE1-OE1 2.77Å; H29-E307 PolarHBondContact CE1-OE1 2.73Å; H29-E307 VanDerWaalsContact NE2-CG 3.32Å; H29-E307 WeakPolarHBondContact NE2-CG 3.49Å; H29-E307 IonicContact NE2-OE1 3.77Å; H29-E307 PolarHBondContact NE2-OE1 3.28Å
30S87.5Confident76.7Confident0 Ų024.5 Ų24.50%014%0.143CC..SBendtrans-69.6-10.5178.468.30000114.2P9 F11 P12 L13 A27 K28 P32P9-S30 WeakPolarHBondContact CB-O 3.48Å; F11-S30 WeakPolarHBondContact O-CA 3.36Å; P12-S30 VanDerWaalsContact O-CB 3.23Å; P12-S30 WeakPolarHBondContact O-CB 3.39Å; L13-S30 WeakPolarHBondContact CD2-O 3.37Å; A27-S30 PolarHBondContact N-OG 2.99Å; A27-S30 VanDerWaalsContact O-CB 3.25Å; A27-S30 WeakPolarHBondContact O-CB 3.38Å; A27-S30 PolarHBondContact O-N 3.11Å; A27-S30 PolarHBondContact O-OG 3.24Å; K28-S30 PolarHBondContact O-N 3.1Å; K28-S30 VanDerWaalsContact O-N 3.08Å; S30-P32 VanDerWaalsContact C-CD 3.44Å; S30-P32 WeakPolarHBondContact O-CD 3.49Å
31L91.4Very high78.3Confident8 Ų826.7 Ų26.74%0.04216%0.155CC..  trans-123.264.4177.6-63.8171.5000110.7L13 A26 H29 W33 H34 L193 M195L13-L31 HydrophobicContact CD2-CD2 3.71Å; L13-L31 HydrophobicContact CD2-CG 4.21Å; A26-L31 HydrophobicContact CB-CD1 3.87Å; H29-L31 PolarHBondContact O-N 3.27Å; H29-L31 VanDerWaalsContact O-N 3.16Å; L31-W33 HydrophobicContact CD2-CZ2 3.71Å; L31-W33 PolarHBondContact O-N 3.35Å; L31-H34 HydrophobicContact CB-CB 4.1Å; L31-H34 VanDerWaalsContact O-CB 3.31Å; L31-H34 WeakPolarHBondContact O-CB 3.28Å; L31-H34 PolarHBondContact O-N 3.42Å; L31-L193 HydrophobicContact CB-CD2 4.1Å; L31-L193 HydrophobicContact CD1-CD2 3.85Å; L31-L193 HydrophobicContact CD1-CG 4.27Å; L31-M195 HydrophobicContact CD1-CB 4.41Å; L31-M195 HydrophobicContact CD1-CE 4.46Å; L31-M195 HydrophobicContact CD1-CG 4.33Å; L31-M195 HydrophobicContact CD1-SD 3.88Å; L31-M195 HydrophobicContact CD2-CE 3.77Å; L31-M195 HydrophobicContact CD2-SD 4.13Å; L31-M195 HydrophobicContact CG-SD 4.27Å
32P93.2Very high79.2Confident2 Ų226.8 Ų26.81%0.01315%0.15CC..THydrogen-bonded Turntrans-72.1-4-169.234.4-40.6000114P9 H29 S30 Y138 T139 V140P9-P32 HydrophobicContact CB-CG 3.86Å; H29-P32 WeakPolarHBondContact O-CD 3.16Å; S30-P32 VanDerWaalsContact C-CD 3.44Å; S30-P32 WeakPolarHBondContact O-CD 3.49Å; P32-Y138 WeakPolarHBondContact CA-O 3.4Å; P32-Y138 VanDerWaalsContact CB-C 3.48Å; P32-Y138 VanDerWaalsContact CB-O 3.25Å; P32-Y138 WeakPolarHBondContact CB-O 3.48Å; P32-T139 WeakPolarHBondContact O-CA 3.07Å; P32-V140 CarbonylContact C-O 3.51Å; P32-V140 VanDerWaalsContact C-O 3.31Å; P32-V140 HydrophobicContact CB-CB 4.22Å; P32-V140 HydrophobicContact CB-CG2 4.47Å; P32-V140 HydrophobicContact CG-CB 3.92Å; P32-V140 HydrophobicContact CG-CG2 4.39Å; P32-V140 PolarHBondContact O-N 3.02Å; P32-V140 VanDerWaalsContact O-N 3.12Å
33W95.8Very high79.4Confident0 Ų029.7 Ų29.70%016%0.164CC..THydrogen-bonded Turntrans-91.1-17.7169.646.379.3000113P9 L31 S54 L55 V140 V142 V247 F254P9-W33 HydrophobicContact CB-CH2 4.33Å; P9-W33 HydrophobicContact CB-CZ3 4.25Å; P9-W33 HydrophobicContact CG-CH2 4.07Å; P9-W33 HydrophobicContact CG-CZ3 4.32Å; L31-W33 HydrophobicContact CD2-CZ2 3.71Å; L31-W33 PolarHBondContact O-N 3.35Å; W33-S54 CarbonylContact O-C 3.45Å; W33-S54 VanDerWaalsContact O-CA 3.27Å; W33-S54 WeakPolarHBondContact O-CA 3.34Å; W33-L55 PolarHBondContact O-N 2.86Å; W33-V140 VanDerWaalsContact CA-O 3.29Å; W33-V140 WeakPolarHBondContact CA-O 3.48Å; W33-V140 WeakPolarHBondContact CB-O 3.02Å; W33-V140 PolarHBondContact N-O 2.02Å; W33-V140 VanDerWaalsContact N-O 3.16Å; W33-V142 HydrophobicContact CB-CB 3.92Å; W33-V142 HydrophobicContact CB-CG1 4.47Å; W33-V142 HydrophobicContact CD2-CB 3.93Å; W33-V142 HydrophobicContact CD2-CG2 4.32Å; W33-V142 HydrophobicContact CE3-CB 4.35Å; W33-V142 HydrophobicContact CG-CB 3.72Å; W33-V142 HydrophobicContact CG-CG2 4.46Å; W33-V247 HydrophobicContact CZ2-CG2 4.43Å; W33-F254 HydrophobicContact CH2-CB 3.6Å; W33-F254 AromaticContact CH2-CD2 3.54Å; W33-F254 HydrophobicContact CH2-CD2 3.54Å; W33-F254 HydrophobicContact CH2-CE2 4.4Å; W33-F254 AromaticContact CH2-CG 3.62Å; W33-F254 HydrophobicContact CH2-CG 3.62Å; W33-F254 HydrophobicContact CZ2-CB 3.83Å; W33-F254 HydrophobicContact CZ2-CD1 4.46Å; W33-F254 HydrophobicContact CZ2-CD2 4.23Å; W33-F254 AromaticContact CZ2-CG 3.91Å; W33-F254 HydrophobicContact CZ2-CG 3.91Å; W33-F254 HydrophobicContact CZ3-CB 4.25Å; W33-F254 HydrophobicContact CZ3-CD2 4.42Å
34H94.3Very high79.1Confident4 Ų434.4 Ų34.42%0.01918%0.179CC..EExtended strand (participates in β ladder)trans-66.2135.2-175.5-173.185.8000110.5L31 S160 H162 L193L31-H34 HydrophobicContact CB-CB 4.1Å; L31-H34 VanDerWaalsContact O-CB 3.31Å; L31-H34 WeakPolarHBondContact O-CB 3.28Å; L31-H34 PolarHBondContact O-N 3.42Å; H34-S160 PolarHBondContact ND1-OG 2.82Å; H34-H162 AromaticContact NE2-CE1 3.77Å; H34-H162 AromaticContact NE2-ND1 3.41Å; H34-H162 PolarHBondContact NE2-ND1 3.47Å; H34-L193 HydrophobicContact CB-CD2 4.08Å; H34-L193 VanDerWaalsContact NE2-CD1 3.34Å; H34-L193 WeakPolarHBondContact NE2-CD1 3.1Å
35V94.2Very high78.9Confident0 Ų036.3 Ų36.30%019%0.19CC..EExtended strand (participates in β ladder)trans-129.8147.1173-55.20000111.3I37 G52 G53 L55 V67 V90 T91 V92V35-I37 HydrophobicContact CG2-CG1 4.19Å; V35-G52 WeakPolarHBondContact O-CA 3.47Å; V35-G53 PolarHBondContact N-O 3.38Å; V35-G53 VanDerWaalsContact N-O 3.1Å; V35-G53 PolarHBondContact O-N 3.4Å; V35-L55 HydrophobicContact CG1-CD1 4.37Å; V35-L55 HydrophobicContact CG1-CD2 4.13Å; V35-L55 HydrophobicContact CG1-CG 3.75Å; V35-V67 HydrophobicContact CG1-CG2 4.49Å; V35-V67 HydrophobicContact CG2-CG1 3.59Å; V35-V67 HydrophobicContact CG2-CG2 4.05Å; V35-V90 HydrophobicContact CB-CG1 3.63Å; V35-V90 HydrophobicContact CG1-CG1 4Å; V35-V90 HydrophobicContact CG2-CG1 3.81Å; V35-T91 WeakPolarHBondContact CA-O 3.48Å; V35-T91 WeakPolarHBondContact CB-O 3.39Å; V35-V92 HydrophobicContact CG1-CB 4.46Å; V35-V92 HydrophobicContact CG1-CG1 3.86Å
36H90.6Very high77.4Confident11 Ų1139.9 Ų39.95%0.05120%0.204CC..EExtended strand (participates in β ladder)trans-101.2125.2172.9177.2-116.6000109.5M38 Q50 V90 T91 V94 V97H36-M38 WeakPolarHBondContact CE1-CG 3.5Å; H36-M38 PolarHBondContact CE1-SD 3.46Å; H36-Q50 WeakPolarHBondContact NE2-CB 3.14Å; H36-Q50 WeakPolarHBondContact NE2-CG 3.24Å; H36-Q50 PolarHBondContact NE2-NE2 3.08Å; H36-Q50 PolarHBondContact NE2-OE1 2.76Å; H36-V90 CarbonylContact O-C 3.47Å; H36-T91 PolarHBondContact N-O 3Å; H36-T91 PolarHBondContact O-N 3.34Å; H36-V94 HydrophobicContact CB-CG1 3.8Å; H36-V97 HydrophobicContact CB-CG1 4.23Å
37I90.3Very high76.3Confident0 Ų043.8 Ų43.80%023%0.227CC..EExtended strand (participates in β ladder)trans-109.2117.4-175.8-51.4176.6000108.3V35 I39 Q50 C51 G52 V67 T69 I88 V90 L127V35-I37 HydrophobicContact CG2-CG1 4.19Å; I37-I39 HydrophobicContact CG2-CD1 3.97Å; I37-I39 HydrophobicContact CG2-CG1 4.18Å; I37-Q50 WeakPolarHBondContact O-CA 3.28Å; I37-C51 HydrophobicContact CB-CB 4.22Å; I37-C51 WeakPolarHBondContact CB-O 3.47Å; I37-C51 PolarHBondContact N-O 2.84Å; I37-C51 PolarHBondContact O-N 3.41Å; I37-G52 VanDerWaalsContact CD1-O 3.27Å; I37-G52 WeakPolarHBondContact CD1-O 3.42Å; I37-V67 HydrophobicContact CD1-CG1 4.05Å; I37-T69 HydrophobicContact CD1-CG2 3.96Å; I37-T69 WeakPolarHBondContact CD1-OG1 3.41Å; I37-I88 HydrophobicContact CG2-CG2 3.69Å; I37-V90 HydrophobicContact CG1-CG2 4.47Å; I37-L127 HydrophobicContact CD1-CD1 3.85Å; I37-L127 HydrophobicContact CG2-CD1 4.2Å
38M84.8Confident75.6Confident27 Ų2744 Ų4413%0.13323%0.231CC..EExtended strand (participates in β ladder)trans-100125.2170.7-73.9-67.6-58.900109.4H36 F40 Q50 I88 I89H36-M38 WeakPolarHBondContact CE1-CG 3.5Å; H36-M38 PolarHBondContact CE1-SD 3.46Å; M38-F40 HydrophobicContact CB-CD2 4.41Å; M38-F40 HydrophobicContact CB-CE1 4.44Å; M38-F40 HydrophobicContact CB-CE2 3.62Å; M38-F40 HydrophobicContact CB-CZ 3.65Å; M38-F40 HydrophobicContact CE-CD1 4.31Å; M38-F40 HydrophobicContact CE-CE1 3.56Å; M38-F40 HydrophobicContact CE-CZ 3.79Å; M38-F40 HydrophobicContact CG-CZ 4.16Å; M38-Q50 HydrophobicContact SD-CG 3.68Å; M38-I88 WeakPolarHBondContact O-CA 3.36Å; M38-I89 PolarHBondContact N-O 3.19Å; M38-I89 PolarHBondContact O-N 2.86Å
39I81.5Confident75.1Confident5 Ų542.9 Ų42.93%0.02623%0.232CC..EExtended strand (participates in β ladder)trans-113.8108174.4-56.5107.7000108.9I37 G48 T49 C51 C73 I83 K87 I88I37-I39 HydrophobicContact CG2-CD1 3.97Å; I37-I39 HydrophobicContact CG2-CG1 4.18Å; I39-G48 CarbonylContact O-C 3.21Å; I39-G48 WeakPolarHBondContact O-CA 3.39Å; I39-T49 PolarHBondContact N-O 2.75Å; I39-T49 PolarHBondContact O-N 2.9Å; I39-C51 HydrophobicContact CD1-CB 4.43Å; I39-C73 WeakPolarHBondContact CD1-O 3.49Å; I39-I83 HydrophobicContact CG2-CB 4.49Å; I39-I83 HydrophobicContact CG2-CD1 3.72Å; I39-I83 HydrophobicContact CG2-CG2 3.73Å; I39-K87 WeakPolarHBondContact CA-O 3.26Å; I39-I88 HydrophobicContact CG1-CG1 4.24Å; I39-I88 HydrophobicContact CG1-CG2 4.3Å; I39-I88 HydrophobicContact CG2-CG1 4.33Å
40F73.8Confident75Confident15 Ų1544.1 Ų44.17%0.06624%0.237CC..EExtended strand (participates in β ladder)trans-85.8138.2-170.7-65.7-78000114M38 E45 V47 K87 I89 R104M38-F40 HydrophobicContact CB-CD2 4.41Å; M38-F40 HydrophobicContact CB-CE1 4.44Å; M38-F40 HydrophobicContact CB-CE2 3.62Å; M38-F40 HydrophobicContact CB-CZ 3.65Å; M38-F40 HydrophobicContact CE-CD1 4.31Å; M38-F40 HydrophobicContact CE-CE1 3.56Å; M38-F40 HydrophobicContact CE-CZ 3.79Å; M38-F40 HydrophobicContact CG-CZ 4.16Å; F40-E45 VanDerWaalsContact CD1-CA 3.44Å; F40-E45 HydrophobicContact CD1-CB 3.86Å; F40-E45 HydrophobicContact CD1-CG 4.25Å; F40-E45 WeakPolarHBondContact CD1-O 3.4Å; F40-E45 HydrophobicContact CD2-CG 4.06Å; F40-E45 HydrophobicContact CE1-CB 3.81Å; F40-E45 HydrophobicContact CE1-CG 4.34Å; F40-E45 WeakPolarHBondContact CE1-O 3.49Å; F40-E45 HydrophobicContact CE2-CB 4.5Å; F40-E45 HydrophobicContact CE2-CG 4.18Å; F40-E45 HydrophobicContact CG-CB 4.21Å; F40-E45 HydrophobicContact CG-CG 4.09Å; F40-E45 HydrophobicContact CZ-CB 4.14Å; F40-E45 HydrophobicContact CZ-CG 4.31Å; F40-V47 WeakPolarHBondContact CA-O 3.37Å; F40-K87 PolarHBondContact N-O 2.85Å; F40-K87 WeakPolarHBondContact O-CD 3.31Å; F40-I89 HydrophobicContact CD2-CD1 4.37Å; F40-I89 HydrophobicContact CE2-CB 4.12Å; F40-I89 HydrophobicContact CE2-CD1 3.9Å; F40-I89 HydrophobicContact CE2-CG1 4.18Å; F40-R104 VanDerWaalsContact CZ-NH2 3.27Å
41N64.1Low75Confident92 Ų9244.4 Ų44.449%0.49224%0.239SC..SBendtrans-64.5-44.1177.9-56.315.8000110.5V47 G48 K87N41-V47 PolarHBondContact N-O 2.76Å; N41-V47 WeakPolarHBondContact ND2-CG1 3.29Å; N41-V47 PolarHBondContact OD1-O 3.3Å; N41-G48 WeakPolarHBondContact OD1-CA 3.13Å; N41-K87 PolarHBondContact O-NZ 2.88Å
42S57.1Low75Confident41 Ų4144 Ų4429%0.28724%0.238SC..SBendtrans-128.2161.7-172.8610000111.5E44 E45S42-E44 PolarHBondContact O-N 2.85Å; S42-E45 PolarHBondContact O-N 2.77Å
43V52.7Low75.1Confident141 Ų14144 Ų4486%0.85524%0.237SC*.THydrogen-bonded Turntrans-63.5-19.6175.7-173.50000112E45V43-E45 PolarHBondContact O-N 3.38Å
44E52.5Low75.1Confident126 Ų12644 Ų4459%0.58924%0.237SC*.THydrogen-bonded Turntrans-74.7-2.5179.8-59.2171-153.400114.2S42 K46S42-E44 PolarHBondContact O-N 2.85Å; E44-K46 HydrophobicContact CB-CD 4.17Å; E44-K46 HydrophobicContact CB-CG 4.13Å; E44-K46 PolarHBondContact O-N 3.16Å; E44-K46 WeakPolarHBondContact OE2-CD 3.49Å; E44-K46 VanDerWaalsContact OE2-CE 3.23Å; E44-K46 WeakPolarHBondContact OE2-CE 3.44Å; E44-K46 IonicContact OE2-NZ 2.71Å; E44-K46 PolarHBondContact OE2-NZ 2.76Å
45E60.1Low75.3Confident79 Ų7943.8 Ų43.837%0.36924%0.236SC..  trans54.815.1-179.4-63-168-171.100116.5F40 S42 V43 I89 R104F40-E45 VanDerWaalsContact CD1-CA 3.44Å; F40-E45 HydrophobicContact CD1-CB 3.86Å; F40-E45 HydrophobicContact CD1-CG 4.25Å; F40-E45 WeakPolarHBondContact CD1-O 3.4Å; F40-E45 HydrophobicContact CD2-CG 4.06Å; F40-E45 HydrophobicContact CE1-CB 3.81Å; F40-E45 HydrophobicContact CE1-CG 4.34Å; F40-E45 WeakPolarHBondContact CE1-O 3.49Å; F40-E45 HydrophobicContact CE2-CB 4.5Å; F40-E45 HydrophobicContact CE2-CG 4.18Å; F40-E45 HydrophobicContact CG-CB 4.21Å; F40-E45 HydrophobicContact CG-CG 4.09Å; F40-E45 HydrophobicContact CZ-CB 4.14Å; F40-E45 HydrophobicContact CZ-CG 4.31Å; S42-E45 PolarHBondContact O-N 2.77Å; V43-E45 PolarHBondContact O-N 3.38Å; E45-I89 WeakPolarHBondContact OE1-CD1 3.24Å; E45-R104 IonicContact OE1-NH2 3.24Å; E45-R104 IonicContact OE2-CZ 3.23Å; E45-R104 VanDerWaalsContact OE2-CZ 3.24Å; E45-R104 IonicContact OE2-NH1 2.75Å; E45-R104 PolarHBondContact OE2-NH1 2.93Å; E45-R104 IonicContact OE2-NH2 2.72Å; E45-R104 PolarHBondContact OE2-NH2 2.98Å
46K43.4Very low75.4Confident158 Ų15843.8 Ų43.869%0.68724%0.237SC*.SBendtrans-73.7-32.4-174.3-69.4174.6-176.5163.10114.9E44E44-K46 HydrophobicContact CB-CD 4.17Å; E44-K46 HydrophobicContact CB-CG 4.13Å; E44-K46 PolarHBondContact O-N 3.16Å; E44-K46 WeakPolarHBondContact OE2-CD 3.49Å; E44-K46 VanDerWaalsContact OE2-CE 3.23Å; E44-K46 WeakPolarHBondContact OE2-CE 3.44Å; E44-K46 IonicContact OE2-NZ 2.71Å; E44-K46 PolarHBondContact OE2-NZ 2.76Å
47V53.2Low75.4Confident85 Ų8545.5 Ų45.552%0.51524%0.243SC..SBendtrans-140.2140.3-176.6-172.10000108.4F40 N41F40-V47 WeakPolarHBondContact CA-O 3.37Å; N41-V47 PolarHBondContact N-O 2.76Å; N41-V47 WeakPolarHBondContact ND2-CG1 3.29Å; N41-V47 PolarHBondContact OD1-O 3.3Å
48G62.7Low75.3Confident23 Ų2348.6 Ų48.624%0.23726%0.259CS..EExtended strand (participates in β ladder)trans-157.9163.9177.300000112.6I39 N41I39-G48 CarbonylContact O-C 3.21Å; I39-G48 WeakPolarHBondContact O-CA 3.39Å; N41-G48 WeakPolarHBondContact OD1-CA 3.13Å
49T71.7Confident75.2Confident66 Ų6649.7 Ų49.741%0.40528%0.277SS..EExtended strand (participates in β ladder)trans-87.1155.9165.153.40000110.3I39I39-T49 PolarHBondContact N-O 2.75Å; I39-T49 PolarHBondContact O-N 2.9Å
50Q80.5Confident75Confident43 Ų4354 Ų5420%0.20131%0.313CS..EExtended strand (participates in β ladder)trans-118.2136.9-177.9-53.7-160.81.900110.8H36 I37 M38 L189H36-Q50 WeakPolarHBondContact NE2-CB 3.14Å; H36-Q50 WeakPolarHBondContact NE2-CG 3.24Å; H36-Q50 PolarHBondContact NE2-NE2 3.08Å; H36-Q50 PolarHBondContact NE2-OE1 2.76Å; I37-Q50 WeakPolarHBondContact O-CA 3.28Å; M38-Q50 HydrophobicContact SD-CG 3.68Å; Q50-L189 VanDerWaalsContact CD-CD1 3.47Å; Q50-L189 HydrophobicContact CG-CD1 4.11Å
51C88.1Confident75.5Confident6 Ų655.3 Ų55.34%0.04133%0.331CS..EExtended strand (participates in β ladder)trans-136.2160.2170.5-81.90000110.9I37 I39 C73 S242I37-C51 HydrophobicContact CB-CB 4.22Å; I37-C51 WeakPolarHBondContact CB-O 3.47Å; I37-C51 PolarHBondContact N-O 2.84Å; I37-C51 PolarHBondContact O-N 3.41Å; I39-C51 HydrophobicContact CD1-CB 4.43Å; C51-C73 HydrophobicContact CB-CB 3.79Å; C51-C73 WeakPolarHBondContact CB-SG 3.47Å; C51-C73 WeakPolarHBondContact SG-CB 3.25Å; C51-C73 CovalentContact SG-SG 2.03Å; C51-C73 PolarHBondContact SG-SG 2.94Å; C51-S242 CarbonylContact C-O 3.59Å; C51-S242 VanDerWaalsContact CA-O 3.31Å; C51-S242 WeakPolarHBondContact CA-O 3.28Å; C51-S242 WeakPolarHBondContact CB-O 3.33Å; C51-S242 VanDerWaalsContact SG-CB 3.56Å
52G90.7Very high76.7Confident1 Ų155.4 Ų55.41%0.0133%0.331CS..EExtended strand (participates in β ladder)trans-88.5170.9162.800000112.3V35 I37 T69 S242 G243V35-G52 WeakPolarHBondContact O-CA 3.47Å; I37-G52 VanDerWaalsContact CD1-O 3.27Å; I37-G52 WeakPolarHBondContact CD1-O 3.42Å; G52-T69 PolarHBondContact O-OG1 3.05Å; G52-S242 PolarHBondContact N-O 3.38Å; G52-G243 CarbonylContact O-C 3.57Å; G52-G243 WeakPolarHBondContact O-CA 3.47Å
53G94.3Very high78.3Confident0 Ų056.1 Ų56.10%033%0.331CS..EExtended strand (participates in β ladder)trans-165.4-175.8168.100000111.4V35 L68 G243V35-G53 PolarHBondContact N-O 3.38Å; V35-G53 VanDerWaalsContact N-O 3.1Å; V35-G53 PolarHBondContact O-N 3.4Å; G53-L68 CarbonylContact C-O 3.54Å; G53-L68 WeakPolarHBondContact CA-O 3.46Å; G53-G243 WeakPolarHBondContact CA-O 3.48Å
54S97.2Very high80.3Confident0 Ų049.5 Ų49.50%029%0.291CS..EExtended strand (participates in β ladder)trans-132.5139.1174.550.80000113.2W33 I56 V67 L68 Q256W33-S54 CarbonylContact O-C 3.45Å; W33-S54 VanDerWaalsContact O-CA 3.27Å; W33-S54 WeakPolarHBondContact O-CA 3.34Å; S54-I56 PolarHBondContact O-N 2.93Å; S54-V67 CarbonylContact O-C 3.57Å; S54-V67 VanDerWaalsContact O-CA 3.3Å; S54-V67 WeakPolarHBondContact O-CA 3.41Å; S54-L68 PolarHBondContact N-O 2.91Å; S54-L68 PolarHBondContact O-N 3.37Å; S54-Q256 PolarHBondContact OG-OE1 3.42Å
55L96.8Very high82.3Confident0 Ų045.8 Ų45.80%028%0.276CS..EExtended strand (participates in β ladder)trans-66.5126.9162.7-68.1172.4000109.3W33 V35 V67 V92 L129 V133 P141 V142W33-L55 PolarHBondContact O-N 2.86Å; V35-L55 HydrophobicContact CG1-CD1 4.37Å; V35-L55 HydrophobicContact CG1-CD2 4.13Å; V35-L55 HydrophobicContact CG1-CG 3.75Å; L55-V67 HydrophobicContact CD2-CG2 4.04Å; L55-V92 HydrophobicContact CD2-CG1 4.36Å; L55-L129 HydrophobicContact CD2-CD1 4.18Å; L55-V133 HydrophobicContact CD1-CG1 4.14Å; L55-V133 HydrophobicContact CD2-CG2 4.17Å; L55-P141 HydrophobicContact CB-CB 4.4Å; L55-P141 WeakPolarHBondContact O-CA 3.06Å; L55-P141 VanDerWaalsContact O-CB 3.31Å; L55-P141 WeakPolarHBondContact O-CB 3.35Å; L55-V142 PolarHBondContact O-N 2.91Å
56I96.3Very high84Confident1 Ų142.1 Ų42.11%0.00526%0.258CS..EExtended strand (participates in β ladder)trans-128.4152.1178.658.7159.8000111.3S54 S64 M66 L68 L126 V142 L144 I286S54-I56 PolarHBondContact O-N 2.93Å; I56-S64 PolarHBondContact O-OG 3.3Å; I56-M66 HydrophobicContact CD1-CE 3.75Å; I56-M66 HydrophobicContact CD1-CG 4.15Å; I56-M66 HydrophobicContact CD1-SD 4.39Å; I56-M66 HydrophobicContact CG1-CB 4.31Å; I56-M66 HydrophobicContact CG1-CE 4.17Å; I56-M66 HydrophobicContact CG1-CG 4.11Å; I56-M66 PolarHBondContact N-O 3.19Å; I56-L68 HydrophobicContact CD1-CB 3.98Å; I56-L68 HydrophobicContact CG1-CB 4.24Å; I56-L68 HydrophobicContact CG2-CB 4.01Å; I56-L68 HydrophobicContact CG2-CD2 4.33Å; I56-L126 HydrophobicContact CD1-CD2 3.92Å; I56-V142 HydrophobicContact CG2-CG1 3.97Å; I56-L144 HydrophobicContact CB-CD2 4.36Å; I56-L144 HydrophobicContact CB-CG 4.49Å; I56-L144 HydrophobicContact CD1-CD1 4.42Å; I56-L144 HydrophobicContact CD1-CD2 4.4Å; I56-L144 HydrophobicContact CG2-CD2 3.95Å; I56-L144 HydrophobicContact CG2-CG 4.48Å; I56-I286 HydrophobicContact CD1-CG2 3.97Å
57R91.3Very high86.6Confident47 Ų4734.6 Ų34.618%0.17723%0.226CC..  trans-124.9140.3173.573.1176.2-165.3165.816.3111.3D2 F4 Y135 P141D2-R57 IonicContact OD2-CZ 3Å; D2-R57 VanDerWaalsContact OD2-CZ 3.23Å; D2-R57 IonicContact OD2-NH1 3.95Å; D2-R57 PolarHBondContact OD2-NH1 3Å; D2-R57 IonicContact OD2-NH2 2.64Å; D2-R57 PolarHBondContact OD2-NH2 3.38Å; F4-R57 PolarHBondContact O-NH1 3.11Å; F4-R57 VanDerWaalsContact O-NH1 3.16Å; R57-Y135 WeakPolarHBondContact CB-OH 3.45Å; R57-P141 HydrophobicContact CB-CB 4.35Å; R57-P141 HydrophobicContact CB-CG 4.07Å; R57-P141 HydrophobicContact CG-CB 4.35Å; R57-P141 HydrophobicContact CG-CG 3.85Å
58L88.7Confident88.7Confident65 Ų6530.6 Ų30.634%0.3420%0.201SC..SBendtrans-105.2-25.5171.3-67.1-178.6000113.5M66 L144 I286 E287 D290L58-M66 HydrophobicContact CD1-CE 3.7Å; L58-M66 HydrophobicContact CG-CE 3.77Å; L58-L144 HydrophobicContact CD2-CD1 3.54Å; L58-I286 HydrophobicContact CD1-CG2 4.22Å; L58-I286 HydrophobicContact CD2-CG2 4.04Å; L58-I286 HydrophobicContact CG-CG2 4.46Å; L58-E287 HydrophobicContact CD1-CG 4.32Å; L58-E287 HydrophobicContact CD2-CG 4.01Å; L58-D290 HydrophobicContact CD1-CB 3.45Å; L58-D290 VanDerWaalsContact CD1-CB 3.45Å
59G81.5Confident90.3Very high50 Ų5029.5 Ų29.552%0.51519%0.19SC..SBendtrans-114173-178.400000113.4
60A78.8Confident91.3Very high95 Ų9526.3 Ų26.379%0.78517%0.171SC*.SBendtrans-69.8149.216300000110.2
61G83.6Confident91.9Very high42 Ų4224.3 Ų24.343%0.43316%0.161SC..SBendtrans149177-179.400000112.1Y135G61-Y135 VanDerWaalsContact O-CE2 3.25Å; G61-Y135 WeakPolarHBondContact O-CE2 3.38Å
62N89.4Confident91.8Very high94 Ų9425.7 Ų25.750%0.50317%0.167SC..SBendtrans-111.721.417963.2-27.3000112.9Y135N62-Y135 HydrophobicContact CB-CD2 4.38Å; N62-Y135 PolarHBondContact O-N 3.08Å
63I90.8Very high91.7Very high56 Ų5625.9 Ų25.929%0.28717%0.168SC..EExtended strand (participates in β ladder)trans-142.1136.5-174.3-55.5-176.1000110V133 Y135 N299I63-V133 CarbonylContact C-O 3.54Å; I63-V133 VanDerWaalsContact CA-O 3.28Å; I63-V133 WeakPolarHBondContact CA-O 3.4Å; I63-Y135 VanDerWaalsContact C-CE1 3.41Å; I63-Y135 PolarHBondContact O-OH 3.37Å; I63-N299 HydrophobicContact CD1-CB 3.92Å; I63-N299 VanDerWaalsContact CD1-CG 3.41Å; I63-N299 WeakPolarHBondContact CD1-OD1 3.06Å
64S94.4Very high91.5Very high2 Ų225.9 Ų25.91%0.01417%0.168CC..EExtended strand (participates in β ladder)trans-112.9131.5165.9-81.20000109.5I56 V133 Y135I56-S64 PolarHBondContact O-OG 3.3Å; S64-V133 PolarHBondContact N-O 3.09Å; S64-V133 WeakPolarHBondContact O-CB 3.42Å; S64-V133 PolarHBondContact O-N 2.81Å; S64-Y135 PolarHBondContact N-OH 2.87Å; S64-Y135 VanDerWaalsContact OG-CE1 3.23Å; S64-Y135 WeakPolarHBondContact OG-CE1 3.35Å; S64-Y135 PolarHBondContact OG-OH 2.95Å
65N95Very high91Very high49 Ų4927 Ų2726%0.26217%0.173SC..EExtended strand (participates in β ladder)trans-122.111.618070.1-6.8000113R128 L129 S296N65-R128 PolarHBondContact ND2-NH1 2.88Å; N65-R128 WeakPolarHBondContact O-CD 3.44Å; N65-R128 PolarHBondContact OD1-NH1 3.44Å; N65-L129 PolarHBondContact O-N 3.39Å; N65-S296 WeakPolarHBondContact CB-OG 3.41Å; N65-S296 PolarHBondContact ND2-OG 2.86Å
66M96.1Very high90.2Very high2 Ų229.6 Ų29.61%0.0119%0.187CC..EExtended strand (participates in β ladder)trans-133.4132.5-172.9-174.516155.900110.2I56 L58 L126 L127 I286 D290I56-M66 HydrophobicContact CD1-CE 3.75Å; I56-M66 HydrophobicContact CD1-CG 4.15Å; I56-M66 HydrophobicContact CD1-SD 4.39Å; I56-M66 HydrophobicContact CG1-CB 4.31Å; I56-M66 HydrophobicContact CG1-CE 4.17Å; I56-M66 HydrophobicContact CG1-CG 4.11Å; I56-M66 PolarHBondContact N-O 3.19Å; L58-M66 HydrophobicContact CD1-CE 3.7Å; L58-M66 HydrophobicContact CG-CE 3.77Å; M66-L126 HydrophobicContact CG-CD2 4.04Å; M66-L126 HydrophobicContact SD-CB 4.4Å; M66-L126 HydrophobicContact SD-CD1 3.99Å; M66-L126 HydrophobicContact SD-CD2 3.9Å; M66-L126 HydrophobicContact SD-CG 4.32Å; M66-L127 WeakPolarHBondContact CA-O 3.47Å; M66-I286 HydrophobicContact CE-CG2 4Å; M66-D290 HydrophobicContact CE-CB 4.21Å; M66-D290 HydrophobicContact SD-CB 4.33Å
67V97.5Very high89.1Confident0 Ų031.8 Ų31.80%020%0.202CC..EExtended strand (participates in β ladder)trans-111.4134.3174.4169.30000109.2V35 I37 S54 L55 V90 L126 L127 L129V35-V67 HydrophobicContact CG1-CG2 4.49Å; V35-V67 HydrophobicContact CG2-CG1 3.59Å; V35-V67 HydrophobicContact CG2-CG2 4.05Å; I37-V67 HydrophobicContact CD1-CG1 4.05Å; S54-V67 CarbonylContact O-C 3.57Å; S54-V67 VanDerWaalsContact O-CA 3.3Å; S54-V67 WeakPolarHBondContact O-CA 3.41Å; L55-V67 HydrophobicContact CD2-CG2 4.04Å; V67-V90 HydrophobicContact CG2-CG1 3.99Å; V67-V90 HydrophobicContact CG2-CG2 4.42Å; V67-L126 WeakPolarHBondContact O-CA 3.21Å; V67-L127 HydrophobicContact CB-CB 4.23Å; V67-L127 HydrophobicContact CB-CD1 4.48Å; V67-L127 HydrophobicContact CG1-CD1 4.23Å; V67-L127 PolarHBondContact N-O 2.86Å; V67-L127 PolarHBondContact O-N 3.06Å; V67-L129 HydrophobicContact CG2-CD1 4.18Å; V67-L129 HydrophobicContact CG2-CD2 3.98Å; V67-L129 HydrophobicContact CG2-CG 4.25Å
68L97.6Very high88.2Confident0 Ų037.9 Ų37.90%023%0.233CC..EExtended strand (participates in β ladder)trans-97134.2170.6-178.566.3000109.7G53 S54 I56 I124 L126 L144 I259 L279 I286G53-L68 CarbonylContact C-O 3.54Å; G53-L68 WeakPolarHBondContact CA-O 3.46Å; S54-L68 PolarHBondContact N-O 2.91Å; S54-L68 PolarHBondContact O-N 3.37Å; I56-L68 HydrophobicContact CD1-CB 3.98Å; I56-L68 HydrophobicContact CG1-CB 4.24Å; I56-L68 HydrophobicContact CG2-CB 4.01Å; I56-L68 HydrophobicContact CG2-CD2 4.33Å; L68-I124 HydrophobicContact CD1-CD1 3.81Å; L68-I124 HydrophobicContact CD1-CG1 3.77Å; L68-L126 HydrophobicContact CB-CD2 4.4Å; L68-L126 HydrophobicContact CD1-CD2 3.72Å; L68-L144 HydrophobicContact CD2-CD2 4.39Å; L68-I259 HydrophobicContact CD1-CD1 3.8Å; L68-I259 HydrophobicContact CD2-CD1 4.1Å; L68-I259 HydrophobicContact CD2-CG1 4.29Å; L68-I259 HydrophobicContact CG-CD1 3.83Å; L68-I259 HydrophobicContact CG-CG1 4.32Å; L68-L279 HydrophobicContact CD1-CD1 4.41Å; L68-L279 HydrophobicContact CD2-CD1 3.65Å; L68-L279 HydrophobicContact CD2-CD2 3.55Å; L68-L279 HydrophobicContact CD2-CG 4.28Å; L68-I286 HydrophobicContact CD1-CD1 4.01Å; L68-I286 HydrophobicContact CD2-CD1 4.49Å
69T95.6Very high87.8Confident0 Ų039.8 Ų39.80%024%0.243CC..EExtended strand (participates in β ladder)trans-153.9-174.5178.5-169.80000110.4I37 G52 A125 L127 G243I37-T69 HydrophobicContact CD1-CG2 3.96Å; I37-T69 WeakPolarHBondContact CD1-OG1 3.41Å; G52-T69 PolarHBondContact O-OG1 3.05Å; T69-A125 HydrophobicContact CG2-CB 4.01Å; T69-A125 PolarHBondContact N-O 3.12Å; T69-A125 PolarHBondContact O-N 2.95Å; T69-L127 HydrophobicContact CG2-CD1 4.15Å; T69-L127 HydrophobicContact CG2-CD2 4.27Å; T69-L127 HydrophobicContact CG2-CG 4.1Å; T69-G243 WeakPolarHBondContact OG1-CA 3.4Å
70A92.9Very high87.9Confident0 Ų046.9 Ų46.90%025%0.254CS..  trans-83.9150.9177.400000111.6H72 C73 D123 I259A70-H72 VanDerWaalsContact C-N 3.34Å; A70-H72 WeakPolarHBondContact CB-ND1 3.25Å; A70-C73 WeakPolarHBondContact O-CB 3.43Å; A70-C73 PolarHBondContact O-N 2.95Å; A70-D123 WeakPolarHBondContact CB-OD1 3.41Å; A70-I259 HydrophobicContact CB-CG2 4.04Å
71A93.7Very high88.4Confident0 Ų051.1 Ų51.10%025%0.25CS..G310 helixtrans-64-40.9175.400000111.5C73 I74 F75 M112 Y115 D123A71-C73 PolarHBondContact O-N 3.44Å; A71-C73 VanDerWaalsContact O-N 3.08Å; A71-I74 PolarHBondContact O-N 2.74Å; A71-F75 WeakPolarHBondContact O-CB 3.34Å; A71-F75 PolarHBondContact O-N 3.11Å; A71-F75 VanDerWaalsContact O-N 3.09Å; A71-M112 HydrophobicContact CB-CG 3.48Å; A71-M112 VanDerWaalsContact CB-CG 3.48Å; A71-M112 HydrophobicContact CB-SD 3.8Å; A71-Y115 HydrophobicContact CB-CD1 3.89Å; A71-Y115 HydrophobicContact CB-CD2 3.72Å; A71-Y115 HydrophobicContact CB-CE1 4.5Å; A71-Y115 HydrophobicContact CB-CE2 4.34Å; A71-Y115 HydrophobicContact CB-CG 3.47Å; A71-Y115 VanDerWaalsContact CB-CG 3.47Å; A71-D123 WeakPolarHBondContact CA-OD1 3.43Å; A71-D123 WeakPolarHBondContact CB-OD1 3.41Å; A71-D123 PolarHBondContact N-OD1 3.14Å
72H86Confident88.6Confident35 Ų3552.8 Ų52.816%0.16225%0.248CC..G310 helixtrans-63-17-179.177.6-102.4000113.8A70 I74 Y115 D123 S242 F262A70-H72 VanDerWaalsContact C-N 3.34Å; A70-H72 WeakPolarHBondContact CB-ND1 3.25Å; H72-I74 VanDerWaalsContact C-N 3.35Å; H72-Y115 HydrophobicContact CB-CE1 4.39Å; H72-Y115 HydrophobicContact CB-CE2 4.49Å; H72-Y115 WeakPolarHBondContact CB-OH 3.22Å; H72-D123 IonicContact CE1-OD2 3.09Å; H72-D123 IonicContact CG-OD1 2.67Å; H72-D123 IonicContact CG-OD2 3.06Å; H72-D123 PolarHBondContact N-OD1 2.04Å; H72-D123 IonicContact ND1-OD1 3.62Å; H72-D123 PolarHBondContact ND1-OD1 2.83Å; H72-D123 IonicContact ND1-OD2 3.97Å; H72-D123 PolarHBondContact ND1-OD2 2.9Å; H72-S242 WeakPolarHBondContact NE2-CB 3.44Å; H72-S242 PolarHBondContact NE2-OG 2.75Å; H72-F262 HydrophobicContact CB-CE2 4.17Å; H72-F262 HydrophobicContact CB-CZ 3.7Å; H72-F262 AromaticContact CG-CZ 3.82Å; H72-F262 AromaticContact ND1-CE2 3.89Å; H72-F262 AromaticContact ND1-CZ 3.97Å
73C88.4Confident88.5Confident6 Ų650 Ų504%0.04123%0.233CC..G310 helixtrans-72.3-25.9172.4-69.60000113.5I39 C51 A70 A71I39-C73 WeakPolarHBondContact CD1-O 3.49Å; C51-C73 HydrophobicContact CB-CB 3.79Å; C51-C73 WeakPolarHBondContact CB-SG 3.47Å; C51-C73 WeakPolarHBondContact SG-CB 3.25Å; C51-C73 CovalentContact SG-SG 2.03Å; C51-C73 PolarHBondContact SG-SG 2.94Å; A70-C73 WeakPolarHBondContact O-CB 3.43Å; A70-C73 PolarHBondContact O-N 2.95Å; A71-C73 PolarHBondContact O-N 3.44Å; A71-C73 VanDerWaalsContact O-N 3.08Å
74I89.5Confident88.4Confident0 Ų050.4 Ų50.40%024%0.24CC..THydrogen-bonded Turntrans-1217.6-175.766.8161.1000113.8A71 H72 I82 I83 I88 V110 M112 A125 L127A71-I74 PolarHBondContact O-N 2.74Å; H72-I74 VanDerWaalsContact C-N 3.35Å; I74-I82 HydrophobicContact CD1-CG2 4.26Å; I74-I82 WeakPolarHBondContact O-CA 3.15Å; I74-I83 WeakPolarHBondContact O-CG1 3.35Å; I74-I83 PolarHBondContact O-N 3Å; I74-I88 HydrophobicContact CB-CD1 4.33Å; I74-I88 HydrophobicContact CG2-CD1 3.77Å; I74-V110 HydrophobicContact CD1-CB 4.02Å; I74-V110 HydrophobicContact CD1-CG1 4.42Å; I74-M112 HydrophobicContact CD1-CB 4.48Å; I74-A125 HydrophobicContact CD1-CB 3.48Å; I74-A125 VanDerWaalsContact CD1-CB 3.48Å; I74-A125 HydrophobicContact CG1-CB 3.79Å; I74-L127 HydrophobicContact CD1-CD2 4.27Å; I74-L127 HydrophobicContact CG2-CD2 3.85Å
75F87Confident88.2Confident24 Ų2451.9 Ų51.911%0.10525%0.249CC..EExtended strand (participates in β ladder)trans-115.4117.5180-171.5-105.1000110.9A71 S77 R80 I82 M112 Y115A71-F75 WeakPolarHBondContact O-CB 3.34Å; A71-F75 PolarHBondContact O-N 3.11Å; A71-F75 VanDerWaalsContact O-N 3.09Å; F75-S77 PolarHBondContact O-N 3.4Å; F75-R80 HydrophobicContact CZ-CB 4.15Å; F75-I82 HydrophobicContact CD2-CG1 4.39Å; F75-M112 HydrophobicContact CB-SD 3.81Å; F75-M112 HydrophobicContact CD2-CE 3.68Å; F75-M112 HydrophobicContact CD2-SD 3.85Å; F75-M112 HydrophobicContact CE2-CE 4.06Å; F75-M112 HydrophobicContact CG-CE 4.35Å; F75-M112 HydrophobicContact CG-SD 4.09Å; F75-Y115 HydrophobicContact CB-CD1 4.2Å; F75-Y115 HydrophobicContact CB-CE1 4.22Å; F75-Y115 AromaticContact CD1-CD1 3.86Å; F75-Y115 HydrophobicContact CD1-CD1 3.86Å; F75-Y115 AromaticContact CD1-CE1 3.7Å; F75-Y115 HydrophobicContact CD1-CE1 3.7Å; F75-Y115 HydrophobicContact CE1-CD1 4.38Å; F75-Y115 HydrophobicContact CE1-CE1 4.38Å; F75-Y115 HydrophobicContact CG-CD1 4.04Å; F75-Y115 HydrophobicContact CG-CE1 4.19Å
76D79.7Confident87.8Confident54 Ų5453.3 Ų53.329%0.28926%0.263SS..EExtended strand (participates in β ladder)trans-76.2100.7168.1-179.1-22.6000108.4Q78 N79 R80 R81D76-Q78 VanDerWaalsContact C-N 3.26Å; D76-Q78 PolarHBondContact O-N 3.28Å; D76-Q78 WeakPolarHBondContact OD1-CA 3.32Å; D76-Q78 WeakPolarHBondContact OD1-CB 3.21Å; D76-Q78 PolarHBondContact OD1-N 2.64Å; D76-N79 HydrophobicContact CB-CB 4.47Å; D76-N79 PolarHBondContact OD1-N 3.29Å; D76-N79 PolarHBondContact OD2-ND2 3.24Å; D76-R80 WeakPolarHBondContact O-CA 3.35Å; D76-R80 PolarHBondContact O-N 3.27Å; D76-R81 PolarHBondContact N-O 2.82Å; D76-R81 PolarHBondContact O-N 3.18Å
77S74.2Confident87.2Confident46 Ų4656.6 Ų56.632%0.32228%0.277SS..THydrogen-bonded Turntrans-69-22-178.964.40000113.5F75 D118F75-S77 PolarHBondContact O-N 3.4Å; S77-D118 PolarHBondContact OG-OD2 2.61Å
78Q72.6Confident86.8Confident176 Ų17656.6 Ų56.682%0.82228%0.277SS*.THydrogen-bonded Turntrans-74.8-48.1176.8-57.5-175.91.900110.9D76D76-Q78 VanDerWaalsContact C-N 3.26Å; D76-Q78 PolarHBondContact O-N 3.28Å; D76-Q78 WeakPolarHBondContact OD1-CA 3.32Å; D76-Q78 WeakPolarHBondContact OD1-CB 3.21Å; D76-Q78 PolarHBondContact OD1-N 2.64Å
79N79.9Confident86.4Confident104 Ų10457.1 Ų57.156%0.55628%0.279SS*.THydrogen-bonded Turntrans-89.9-5.5-179.8-67.5-68.5000113.7D76 R81D76-N79 HydrophobicContact CB-CB 4.47Å; D76-N79 PolarHBondContact OD1-N 3.29Å; D76-N79 PolarHBondContact OD2-ND2 3.24Å; N79-R81 VanDerWaalsContact C-N 3.33Å; N79-R81 WeakPolarHBondContact O-CG 3.34Å; N79-R81 PolarHBondContact O-N 3.24Å
80R83.8Confident86.2Confident199 Ų19957.1 Ų57.175%0.75128%0.279SS*.THydrogen-bonded Turntrans51.746.5-174.4-63.7-177.4173-179.6-1.9113F75 D76F75-R80 HydrophobicContact CZ-CB 4.15Å; D76-R80 WeakPolarHBondContact O-CA 3.35Å; D76-R80 PolarHBondContact O-N 3.27Å
81R88Confident86.1Confident185 Ų18557.1 Ų57.170%0.69828%0.28SS*.EExtended strand (participates in β ladder)trans-132.1144.7-175.4-75.1174.5-174.8-1650111.4D76 N79D76-R81 PolarHBondContact N-O 2.82Å; D76-R81 PolarHBondContact O-N 3.18Å; N79-R81 VanDerWaalsContact C-N 3.33Å; N79-R81 WeakPolarHBondContact O-CG 3.34Å; N79-R81 PolarHBondContact O-N 3.24Å
82I89.3Confident86Confident77 Ų7757.2 Ų57.240%0.39528%0.28SS..EExtended strand (participates in β ladder)trans-72.4135.7168.5-57.4173.9000108.1I74 F75 V110 M112I74-I82 HydrophobicContact CD1-CG2 4.26Å; I74-I82 WeakPolarHBondContact O-CA 3.15Å; F75-I82 HydrophobicContact CD2-CG1 4.39Å; I82-V110 HydrophobicContact CG2-CG2 3.58Å; I82-M112 HydrophobicContact CD1-CB 4.42Å; I82-M112 HydrophobicContact CD1-CE 4.47Å; I82-M112 HydrophobicContact CG1-CE 4.31Å; I82-M112 HydrophobicContact CG1-SD 4.46Å
83I86.7Confident86Confident34 Ų3456 Ų5617%0.17428%0.277CS..PPolyproline II helixtrans-71.1130.3179.1-61.5175.5000108.9I39 I74 K87 I88I39-I83 HydrophobicContact CG2-CB 4.49Å; I39-I83 HydrophobicContact CG2-CD1 3.72Å; I39-I83 HydrophobicContact CG2-CG2 3.73Å; I74-I83 WeakPolarHBondContact O-CG1 3.35Å; I74-I83 PolarHBondContact O-N 3Å; I83-K87 HydrophobicContact CG2-CB 4.02Å; I83-K87 HydrophobicContact CG2-CD 4.14Å; I83-I88 HydrophobicContact CG2-CG1 4.36Å
84P88.8Confident85.9Confident66 Ų6656.2 Ų56.243%0.42928%0.278SS..PPolyproline II helixtrans-55.5136.9-178.6-29.135.2000113.4S86 K87P84-S86 PolarHBondContact O-N 2.59Å; P84-K87 PolarHBondContact O-N 2.75Å
85P91Very high85.6Confident33 Ų3357 Ų5721%0.21428%0.282CS..G310 helixtrans-49.7-36.2178.5-29.633.9000114.3K87 I88 V107 V110P85-K87 PolarHBondContact O-N 3.37Å; P85-K87 VanDerWaalsContact O-N 3.13Å; P85-I88 PolarHBondContact O-N 3.28Å; P85-V107 CarbonylContact C-O 3.53Å; P85-V107 HydrophobicContact CB-CB 4.35Å; P85-V107 HydrophobicContact CB-CG1 4.09Å; P85-V107 VanDerWaalsContact CB-O 3.32Å; P85-V107 WeakPolarHBondContact CB-O 3.34Å; P85-V110 HydrophobicContact CG-CG1 4.23Å; P85-V110 HydrophobicContact CG-CG2 4.1Å
86S84.7Confident85.4Confident78 Ų7858 Ų5855%0.54529%0.288SS..G310 helixtrans-60.7-21.7179.854.70000114.7P84 Q106P84-S86 PolarHBondContact O-N 2.59Å; S86-Q106 PolarHBondContact O-NE2 2.96Å
87K84.5Confident85.2Confident71 Ų7156.5 Ų56.531%0.30928%0.281SS..G310 helixtrans-87.8-6.8175.8-68.5-174.8166.6-155.50113.7I39 F40 N41 I83 P84 P85I39-K87 WeakPolarHBondContact CA-O 3.26Å; F40-K87 PolarHBondContact N-O 2.85Å; F40-K87 WeakPolarHBondContact O-CD 3.31Å; N41-K87 PolarHBondContact O-NZ 2.88Å; I83-K87 HydrophobicContact CG2-CB 4.02Å; I83-K87 HydrophobicContact CG2-CD 4.14Å; P84-K87 PolarHBondContact O-N 2.75Å; P85-K87 PolarHBondContact O-N 3.37Å; P85-K87 VanDerWaalsContact O-N 3.13Å
88I89Confident85.3Confident0 Ų056.4 Ų56.40%028%0.278CS..EExtended strand (participates in β ladder)trans-109.9122.4-171.4-51.9170000109I37 M38 I39 I74 I83 P85 V107 V110 L127I37-I88 HydrophobicContact CG2-CG2 3.69Å; M38-I88 WeakPolarHBondContact O-CA 3.36Å; I39-I88 HydrophobicContact CG1-CG1 4.24Å; I39-I88 HydrophobicContact CG1-CG2 4.3Å; I39-I88 HydrophobicContact CG2-CG1 4.33Å; I74-I88 HydrophobicContact CB-CD1 4.33Å; I74-I88 HydrophobicContact CG2-CD1 3.77Å; I83-I88 HydrophobicContact CG2-CG1 4.36Å; P85-I88 PolarHBondContact O-N 3.28Å; I88-V107 HydrophobicContact CB-CB 4.14Å; I88-V107 HydrophobicContact CB-CG2 3.87Å; I88-V107 HydrophobicContact CG2-CB 4.42Å; I88-V107 HydrophobicContact CG2-CG2 3.62Å; I88-V107 PolarHBondContact O-N 3.37Å; I88-V107 VanDerWaalsContact O-N 3.11Å; I88-V110 HydrophobicContact CD1-CG1 4.01Å; I88-L127 HydrophobicContact CG2-CD1 4.05Å
89I88.4Confident85.1Confident11 Ų1149.4 Ų49.46%0.05625%0.251CS..EExtended strand (participates in β ladder)trans-125.8126.6178.5-64.7-179.6000109.2M38 F40 E45 R104M38-I89 PolarHBondContact N-O 3.19Å; M38-I89 PolarHBondContact O-N 2.86Å; F40-I89 HydrophobicContact CD2-CD1 4.37Å; F40-I89 HydrophobicContact CE2-CB 4.12Å; F40-I89 HydrophobicContact CE2-CD1 3.9Å; F40-I89 HydrophobicContact CE2-CG1 4.18Å; E45-I89 WeakPolarHBondContact OE1-CD1 3.24Å; I89-R104 VanDerWaalsContact CD1-NH2 3.34Å; I89-R104 HydrophobicContact CG2-CB 3.77Å; I89-R104 HydrophobicContact CG2-CG 4.28Å
90V91.8Very high84.5Confident0 Ų052.4 Ų52.40%026%0.259CS..EExtended strand (participates in β ladder)trans-98.6133.8177.6-179.60000109V35 H36 I37 V67 V92 R104 I105 V107 L127 L129V35-V90 HydrophobicContact CB-CG1 3.63Å; V35-V90 HydrophobicContact CG1-CG1 4Å; V35-V90 HydrophobicContact CG2-CG1 3.81Å; H36-V90 CarbonylContact O-C 3.47Å; I37-V90 HydrophobicContact CG1-CG2 4.47Å; V67-V90 HydrophobicContact CG2-CG1 3.99Å; V67-V90 HydrophobicContact CG2-CG2 4.42Å; V90-V92 HydrophobicContact CG1-CG1 4.04Å; V90-R104 CarbonylContact O-C 3.58Å; V90-R104 WeakPolarHBondContact O-CA 3.28Å; V90-I105 PolarHBondContact N-O 3.21Å; V90-I105 PolarHBondContact O-N 2.77Å; V90-V107 HydrophobicContact CG2-CG2 3.93Å; V90-L127 HydrophobicContact CG2-CD1 4.07Å; V90-L129 HydrophobicContact CB-CD2 3.82Å; V90-L129 HydrophobicContact CG1-CD2 4.2Å; V90-L129 HydrophobicContact CG2-CD2 3.68Å
91T90.6Very high83.6Confident1 Ų147.5 Ų47.51%0.00625%0.247CC..EExtended strand (participates in β ladder)trans-107.3126.9169.9-45.20000109.3V35 H36 V94 K102 T103V35-T91 WeakPolarHBondContact CA-O 3.48Å; V35-T91 WeakPolarHBondContact CB-O 3.39Å; H36-T91 PolarHBondContact N-O 3Å; H36-T91 PolarHBondContact O-N 3.34Å; T91-V94 HydrophobicContact CG2-CB 3.86Å; T91-V94 HydrophobicContact CG2-CG1 4.18Å; T91-V94 HydrophobicContact CG2-CG2 4.2Å; T91-V94 WeakPolarHBondContact O-CG1 3.36Å; T91-K102 HydrophobicContact CG2-CB 3.8Å; T91-K102 HydrophobicContact CG2-CD 3.76Å; T91-K102 HydrophobicContact CG2-CG 4.05Å; T91-T103 WeakPolarHBondContact CA-O 3.49Å
92V91.6Very high83.1Confident2 Ų241.4 Ų41.41%0.01223%0.226CC..EExtended strand (participates in β ladder)trans-110.9154.1-176.4-56.50000111.6V35 L55 V90 V94 T103 I105 V133 T139 I305V35-V92 HydrophobicContact CG1-CB 4.46Å; V35-V92 HydrophobicContact CG1-CG1 3.86Å; L55-V92 HydrophobicContact CD2-CG1 4.36Å; V90-V92 HydrophobicContact CG1-CG1 4.04Å; V92-V94 PolarHBondContact O-N 2.74Å; V92-V94 VanDerWaalsContact O-N 3.16Å; V92-T103 HydrophobicContact CG2-CG2 3.77Å; V92-T103 PolarHBondContact N-O 3.34Å; V92-T103 VanDerWaalsContact N-O 3.14Å; V92-I105 HydrophobicContact CG1-CD1 3.93Å; V92-I105 HydrophobicContact CG2-CD1 3.98Å; V92-V133 HydrophobicContact CG1-CG2 4.01Å; V92-V133 HydrophobicContact CG2-CG1 4.32Å; V92-V133 HydrophobicContact CG2-CG2 4.42Å; V92-T139 HydrophobicContact CB-CG2 4.4Å; V92-T139 HydrophobicContact CG2-CG2 4.41Å; V92-I305 HydrophobicContact CG2-CD1 4.14Å
93G86.4Confident82.9Confident8 Ų838.3 Ų38.38%0.08221%0.211CC..SBendtrans67.28.7-178.600000114.6H95G93-H95 PolarHBondContact O-N 3.13Å
94V85.8Confident82.9Confident12 Ų1241.8 Ų41.87%0.07322%0.222CC..  trans-79.8116.1-167.258.10000112.8H36 T91 V92 D96 V97H36-V94 HydrophobicContact CB-CG1 3.8Å; T91-V94 HydrophobicContact CG2-CB 3.86Å; T91-V94 HydrophobicContact CG2-CG1 4.18Å; T91-V94 HydrophobicContact CG2-CG2 4.2Å; T91-V94 WeakPolarHBondContact O-CG1 3.36Å; V92-V94 PolarHBondContact O-N 2.74Å; V92-V94 VanDerWaalsContact O-N 3.16Å; V94-D96 WeakPolarHBondContact CG2-O 3.32Å; V94-V97 HydrophobicContact CG2-CG1 4.08Å
95H84.7Confident82.9Confident16 Ų1639 Ų397%0.07420%0.203CC..SBendtrans-88.2-51.9162.5-169.657.9000110.9E25 A26 K28 G93 H162 K192 L193E25-H95 IonicContact OE1-CD2 2.6Å; E25-H95 IonicContact OE1-CE1 3.88Å; E25-H95 IonicContact OE1-NE2 3.28Å; E25-H95 PolarHBondContact OE1-NE2 3.16Å; A26-H95 PolarHBondContact O-CE1 2.94Å; K28-H95 HydrophobicContact CG-CB 4.07Å; G93-H95 PolarHBondContact O-N 3.13Å; H95-H162 PolarHBondContact O-NE2 2.76Å; H95-K192 CarbonylContact O-C 3.57Å; H95-K192 WeakPolarHBondContact O-CA 3.19Å; H95-L193 PolarHBondContact O-N 3.1Å
96D81.6Confident82.8Confident45 Ų4541 Ų4124%0.24121%0.209CC..BIsolated β-bridgetrans-110.6118.5-178.1-170.9-33.8000110.9V94 T98 A99 E191V94-D96 WeakPolarHBondContact CG2-O 3.32Å; D96-T98 PolarHBondContact O-N 3.2Å; D96-T98 WeakPolarHBondContact OD1-CA 3.45Å; D96-T98 VanDerWaalsContact OD1-CB 3.27Å; D96-T98 WeakPolarHBondContact OD1-CB 3.28Å; D96-T98 WeakPolarHBondContact OD1-CG2 3.43Å; D96-T98 PolarHBondContact OD1-N 3.23Å; D96-T98 PolarHBondContact OD1-OG1 3.49Å; D96-A99 VanDerWaalsContact O-CB 3.29Å; D96-A99 WeakPolarHBondContact O-CB 3.49Å; D96-A99 PolarHBondContact O-N 2.89Å; D96-E191 CarbonylContact C-O 3.49Å; D96-E191 WeakPolarHBondContact CA-O 3.31Å
97V76.8Confident83.3Confident23 Ų2337.3 Ų37.314%0.13918%0.184CC..THydrogen-bonded Turntrans-71-16.2-179.4-630000113.1H36 V94 K102 H162 E191H36-V97 HydrophobicContact CB-CG1 4.23Å; V94-V97 HydrophobicContact CG2-CG1 4.08Å; V97-K102 WeakPolarHBondContact O-CE 3.49Å; V97-K102 PolarHBondContact O-NZ 3.4Å; V97-H162 HydrophobicContact CG1-CB 4.46Å; V97-E191 WeakPolarHBondContact CG2-O 3.46Å; V97-E191 PolarHBondContact N-O 2.75Å
98T75.1Confident83.8Confident44 Ų4435.6 Ų35.627%0.2718%0.178SC..THydrogen-bonded Turntrans-81.2-15.7176.376.40000112.8D96 K100 E191 T349D96-T98 PolarHBondContact O-N 3.2Å; D96-T98 WeakPolarHBondContact OD1-CA 3.45Å; D96-T98 VanDerWaalsContact OD1-CB 3.27Å; D96-T98 WeakPolarHBondContact OD1-CB 3.28Å; D96-T98 WeakPolarHBondContact OD1-CG2 3.43Å; D96-T98 PolarHBondContact OD1-N 3.23Å; D96-T98 PolarHBondContact OD1-OG1 3.49Å; T98-K100 PolarHBondContact O-N 2.87Å; T98-E191 HydrophobicContact CG2-CB 3.79Å; T98-E191 HydrophobicContact CG2-CG 3.57Å; T98-T349 HydrophobicContact CG2-CG2 3.69Å
99A68.6Low84.1Confident29 Ų2937.4 Ų37.424%0.2419%0.187CC..  trans-50130.2179.300000111.9D96 K102D96-A99 VanDerWaalsContact O-CB 3.29Å; D96-A99 WeakPolarHBondContact O-CB 3.49Å; D96-A99 PolarHBondContact O-N 2.89Å; A99-K102 HydrophobicContact CB-CB 4.47Å; A99-K102 VanDerWaalsContact O-CG 3.3Å; A99-K102 WeakPolarHBondContact O-CG 3.22Å; A99-K102 PolarHBondContact O-NZ 3.16Å
100K66.5Low84.5Confident167 Ų16738 Ų3873%0.72619%0.191SC*.THydrogen-bonded Turntrans-72.1-42-173-68.3-174.4178.1-178.60113T98 K102T98-K100 PolarHBondContact O-N 2.87Å; K100-K102 VanDerWaalsContact C-N 3.3Å; K100-K102 PolarHBondContact O-N 2.83Å
101D66.5Low84.7Confident96 Ų9638.5 Ų38.551%0.51320%0.196SC..THydrogen-bonded Turntrans-87.56.9-171.9-71.48.8000112.9H306 K314D101-H306 VanDerWaalsContact C-CD2 3.49Å; D101-H306 WeakPolarHBondContact CB-CE1 3.48Å; D101-H306 WeakPolarHBondContact CB-ND1 3.44Å; D101-H306 WeakPolarHBondContact O-CB 3.3Å; D101-H306 IonicContact OD2-CE1 2.66Å; D101-K314 IonicContact OD2-NZ 2.85Å; D101-K314 PolarHBondContact OD2-NZ 3.08Å
102K76.7Confident84.9Confident57 Ų5740 Ų4025%0.24820%0.203CC..  trans-53.9139.1-172.161.1175.1162-86.90114.5T91 V97 A99 K100 R104T91-K102 HydrophobicContact CG2-CB 3.8Å; T91-K102 HydrophobicContact CG2-CD 3.76Å; T91-K102 HydrophobicContact CG2-CG 4.05Å; V97-K102 WeakPolarHBondContact O-CE 3.49Å; V97-K102 PolarHBondContact O-NZ 3.4Å; A99-K102 HydrophobicContact CB-CB 4.47Å; A99-K102 VanDerWaalsContact O-CG 3.3Å; A99-K102 WeakPolarHBondContact O-CG 3.22Å; A99-K102 PolarHBondContact O-NZ 3.16Å; K100-K102 VanDerWaalsContact C-N 3.3Å; K100-K102 PolarHBondContact O-N 2.83Å; K102-R104 HydrophobicContact CD-CG 4.44Å; K102-R104 HydrophobicContact CG-CG 4.16Å; K102-R104 PolarHBondContact O-N 3.05Å
103T84.2Confident84.8Confident12 Ų1240.3 Ų40.37%0.07421%0.206CC..  trans-74.698.9179.5-50.60000111.6T91 V92 I105 L300 S304 I305 H306T91-T103 WeakPolarHBondContact CA-O 3.49Å; V92-T103 HydrophobicContact CG2-CG2 3.77Å; V92-T103 PolarHBondContact N-O 3.34Å; V92-T103 VanDerWaalsContact N-O 3.14Å; T103-I105 HydrophobicContact CG2-CD1 4.45Å; T103-I105 HydrophobicContact CG2-CG1 4.27Å; T103-L300 HydrophobicContact CG2-CD1 3.7Å; T103-S304 WeakPolarHBondContact CG2-O 3.31Å; T103-S304 PolarHBondContact OG1-O 3.26Å; T103-I305 HydrophobicContact CG2-CD1 4.13Å; T103-I305 WeakPolarHBondContact OG1-CA 3.27Å; T103-H306 WeakPolarHBondContact OG1-CB 3.47Å; T103-H306 PolarHBondContact OG1-N 3.27Å
104R86.6Confident85Confident106 Ų10646.2 Ų46.240%0.423%0.232SC..EExtended strand (participates in β ladder)trans-94.9135.5174.7-62.8178.575.5-156.4-2.5110.5F40 E45 I89 V90 K102F40-R104 VanDerWaalsContact CZ-NH2 3.27Å; E45-R104 IonicContact OE1-NH2 3.24Å; E45-R104 IonicContact OE2-CZ 3.23Å; E45-R104 VanDerWaalsContact OE2-CZ 3.24Å; E45-R104 IonicContact OE2-NH1 2.75Å; E45-R104 PolarHBondContact OE2-NH1 2.93Å; E45-R104 IonicContact OE2-NH2 2.72Å; E45-R104 PolarHBondContact OE2-NH2 2.98Å; I89-R104 VanDerWaalsContact CD1-NH2 3.34Å; I89-R104 HydrophobicContact CG2-CB 3.77Å; I89-R104 HydrophobicContact CG2-CG 4.28Å; V90-R104 CarbonylContact O-C 3.58Å; V90-R104 WeakPolarHBondContact O-CA 3.28Å; K102-R104 HydrophobicContact CD-CG 4.44Å; K102-R104 HydrophobicContact CG-CG 4.16Å; K102-R104 PolarHBondContact O-N 3.05Å
105I90.7Very high85Confident7 Ų746 Ų464%0.03623%0.23CC..EExtended strand (participates in β ladder)trans-133126.1-178.1-44.5177.5000108.4V90 V92 T103 L129 V133 L300V90-I105 PolarHBondContact N-O 3.21Å; V90-I105 PolarHBondContact O-N 2.77Å; V92-I105 HydrophobicContact CG1-CD1 3.93Å; V92-I105 HydrophobicContact CG2-CD1 3.98Å; T103-I105 HydrophobicContact CG2-CD1 4.45Å; T103-I105 HydrophobicContact CG2-CG1 4.27Å; I105-L129 HydrophobicContact CD1-CD1 4.28Å; I105-L129 HydrophobicContact CG2-CB 4.06Å; I105-L129 HydrophobicContact CG2-CD2 4.45Å; I105-V133 HydrophobicContact CD1-CG2 3.45Å; I105-V133 VanDerWaalsContact CD1-CG2 3.45Å; I105-L300 HydrophobicContact CD1-CD1 3.5Å; I105-L300 VanDerWaalsContact CD1-CD1 3.5Å; I105-L300 HydrophobicContact CG1-CD1 3.93Å
106Q88.4Confident84.9Confident75 Ų7553.4 Ų53.435%0.3526%0.257SS..EExtended strand (participates in β ladder)trans-75.9147.5176.5-165.917540.200110.9S86 M130S86-Q106 PolarHBondContact O-NE2 2.96Å; Q106-M130 HydrophobicContact CB-CE 4.19Å; Q106-M130 HydrophobicContact CG-CE 4.3Å; Q106-M130 VanDerWaalsContact O-CB 3.28Å; Q106-M130 WeakPolarHBondContact O-CB 3.44Å; Q106-M130 PolarHBondContact O-N 3.19Å; Q106-M130 VanDerWaalsContact OE1-CE 3.25Å
107V94Very high84.7Confident2 Ų256 Ų561%0.01227%0.266CS..EExtended strand (participates in β ladder)trans-81.8134.1172.9-179.40000109.7P85 I88 V90 D109 V110 L127 R128P85-V107 CarbonylContact C-O 3.53Å; P85-V107 HydrophobicContact CB-CB 4.35Å; P85-V107 HydrophobicContact CB-CG1 4.09Å; P85-V107 VanDerWaalsContact CB-O 3.32Å; P85-V107 WeakPolarHBondContact CB-O 3.34Å; I88-V107 HydrophobicContact CB-CB 4.14Å; I88-V107 HydrophobicContact CB-CG2 3.87Å; I88-V107 HydrophobicContact CG2-CB 4.42Å; I88-V107 HydrophobicContact CG2-CG2 3.62Å; I88-V107 PolarHBondContact O-N 3.37Å; I88-V107 VanDerWaalsContact O-N 3.11Å; V90-V107 HydrophobicContact CG2-CG2 3.93Å; V107-D109 WeakPolarHBondContact CG1-O 3.25Å; V107-V110 HydrophobicContact CG1-CG1 3.66Å; V107-L127 HydrophobicContact CG1-CB 3.89Å; V107-L127 HydrophobicContact CG2-CB 3.95Å; V107-L127 HydrophobicContact CG2-CD1 4.14Å; V107-R128 CarbonylContact C-O 3.53Å; V107-R128 WeakPolarHBondContact CA-O 3.44Å; V107-R128 WeakPolarHBondContact CG1-O 3.44Å
108I95.1Very high84.2Confident35 Ų3558.2 Ų58.218%0.17928%0.277CS..EExtended strand (participates in β ladder)trans-94.9-31.3176.5-169.8169.6000112.5R128 M130 L294 K297I108-R128 HydrophobicContact CG2-CB 3.86Å; I108-R128 HydrophobicContact CG2-CG 3.48Å; I108-R128 VanDerWaalsContact CG2-CG 3.48Å; I108-R128 PolarHBondContact N-O 3.07Å; I108-M130 HydrophobicContact CB-CB 4.26Å; I108-L294 HydrophobicContact CG1-CD1 4.43Å; I108-K297 HydrophobicContact CD1-CD 4.28Å; I108-K297 HydrophobicContact CD1-CG 3.88Å
109D96.8Very high84Confident38 Ų3860.1 Ų60.120%0.20328%0.282CS..EExtended strand (participates in β ladder)trans-153.4154.7-176.7-166.315000111.4V107 R128 M293 L294V107-D109 WeakPolarHBondContact CG1-O 3.25Å; D109-R128 HydrophobicContact CB-CB 4.13Å; D109-R128 PolarHBondContact O-N 2.74Å; D109-M293 HydrophobicContact CB-CE 4.33Å; D109-M293 WeakPolarHBondContact O-CE 3.45Å; D109-M293 WeakPolarHBondContact OD2-CA 3.25Å; D109-M293 WeakPolarHBondContact OD2-CB 3.46Å; D109-L294 HydrophobicContact CB-CB 4.02Å; D109-L294 HydrophobicContact CB-CD1 4.26Å; D109-L294 HydrophobicContact CB-CG 4.24Å; D109-L294 PolarHBondContact OD2-N 3.35Å
110V96.4Very high84.5Confident23 Ų2359.5 Ų59.514%0.13927%0.274CS..EExtended strand (participates in β ladder)trans-136.7139-176.8-65.70000111.7I74 I82 P85 I88 V107 L126 L127I74-V110 HydrophobicContact CD1-CB 4.02Å; I74-V110 HydrophobicContact CD1-CG1 4.42Å; I82-V110 HydrophobicContact CG2-CG2 3.58Å; P85-V110 HydrophobicContact CG-CG1 4.23Å; P85-V110 HydrophobicContact CG-CG2 4.1Å; I88-V110 HydrophobicContact CD1-CG1 4.01Å; V107-V110 HydrophobicContact CG1-CG1 3.66Å; V110-L126 WeakPolarHBondContact CA-O 3.42Å; V110-L127 HydrophobicContact CB-CD2 4.44Å; V110-L127 HydrophobicContact CG1-CD2 3.65Å
111A96Very high85.5Confident11 Ų1152.1 Ų52.19%0.09125%0.245CC..EExtended strand (participates in β ladder)trans-127.3142.9171.100000109.7A125 L126 W285 M289 M293A111-A125 CarbonylContact O-C 3.6Å; A111-A125 VanDerWaalsContact O-CA 3.26Å; A111-A125 WeakPolarHBondContact O-CA 3.31Å; A111-L126 HydrophobicContact CB-CB 4.44Å; A111-L126 PolarHBondContact N-O 2.89Å; A111-L126 PolarHBondContact O-N 2.98Å; A111-W285 HydrophobicContact CB-CZ2 4.35Å; A111-M289 HydrophobicContact CB-CB 4.04Å; A111-M289 HydrophobicContact CB-CG 3.95Å; A111-M289 HydrophobicContact CB-SD 4.17Å; A111-M293 HydrophobicContact CB-CE 4.14Å; A111-M293 HydrophobicContact CB-CG 4.01Å; A111-M293 HydrophobicContact CB-SD 3.66Å
112M93.7Very high86.7Confident32 Ų3249 Ų4916%0.15823%0.228CC..EExtended strand (participates in β ladder)trans-129.1149.5-177.4-166.9179.571.200109.5A71 I74 F75 I82 Y115 W285A71-M112 HydrophobicContact CB-CG 3.48Å; A71-M112 VanDerWaalsContact CB-CG 3.48Å; A71-M112 HydrophobicContact CB-SD 3.8Å; I74-M112 HydrophobicContact CD1-CB 4.48Å; F75-M112 HydrophobicContact CB-SD 3.81Å; F75-M112 HydrophobicContact CD2-CE 3.68Å; F75-M112 HydrophobicContact CD2-SD 3.85Å; F75-M112 HydrophobicContact CE2-CE 4.06Å; F75-M112 HydrophobicContact CG-CE 4.35Å; F75-M112 HydrophobicContact CG-SD 4.09Å; I82-M112 HydrophobicContact CD1-CB 4.42Å; I82-M112 HydrophobicContact CD1-CE 4.47Å; I82-M112 HydrophobicContact CG1-CE 4.31Å; I82-M112 HydrophobicContact CG1-SD 4.46Å; M112-Y115 VanDerWaalsContact CE-O 3.31Å; M112-Y115 WeakPolarHBondContact CE-O 3.48Å; M112-Y115 HydrophobicContact SD-CD1 4.28Å; M112-W285 VanDerWaalsContact O-CZ2 3.32Å; M112-W285 WeakPolarHBondContact O-CZ2 3.45Å
113G90.9Very high87.4Confident8 Ų846.2 Ų46.28%0.08222%0.216CC..  trans-58.8178.4165.900000111.6Y115 I124G113-Y115 PolarHBondContact O-N 3.37Å; G113-I124 PolarHBondContact N-O 3.48Å
114E90.3Very high87.9Confident133 Ų13345.7 Ų45.762%0.62121%0.213SC*.SBendtrans-73.641.4174.9-64.1-169.9-160.800113.1R116E114-R116 WeakPolarHBondContact O-CG 3.09Å; E114-R116 IonicContact OE2-NH2 3.9Å; E114-R116 PolarHBondContact OE2-NH2 2.85Å
115Y85.2Confident88.4Confident7 Ų740.6 Ų40.63%0.02719%0.193CC..  trans-72125.3-179.8-175.7-91.1000110.8A71 H72 F75 M112 G113 K117 D118 D120 D123 F262A71-Y115 HydrophobicContact CB-CD1 3.89Å; A71-Y115 HydrophobicContact CB-CD2 3.72Å; A71-Y115 HydrophobicContact CB-CE1 4.5Å; A71-Y115 HydrophobicContact CB-CE2 4.34Å; A71-Y115 HydrophobicContact CB-CG 3.47Å; A71-Y115 VanDerWaalsContact CB-CG 3.47Å; H72-Y115 HydrophobicContact CB-CE1 4.39Å; H72-Y115 HydrophobicContact CB-CE2 4.49Å; H72-Y115 WeakPolarHBondContact CB-OH 3.22Å; F75-Y115 HydrophobicContact CB-CD1 4.2Å; F75-Y115 HydrophobicContact CB-CE1 4.22Å; F75-Y115 AromaticContact CD1-CD1 3.86Å; F75-Y115 HydrophobicContact CD1-CD1 3.86Å; F75-Y115 AromaticContact CD1-CE1 3.7Å; F75-Y115 HydrophobicContact CD1-CE1 3.7Å; F75-Y115 HydrophobicContact CE1-CD1 4.38Å; F75-Y115 HydrophobicContact CE1-CE1 4.38Å; F75-Y115 HydrophobicContact CG-CD1 4.04Å; F75-Y115 HydrophobicContact CG-CE1 4.19Å; M112-Y115 VanDerWaalsContact CE-O 3.31Å; M112-Y115 WeakPolarHBondContact CE-O 3.48Å; M112-Y115 HydrophobicContact SD-CD1 4.28Å; G113-Y115 PolarHBondContact O-N 3.37Å; Y115-K117 WeakPolarHBondContact CE2-O 3.19Å; Y115-K117 PolarHBondContact OH-O 2.97Å; Y115-D118 WeakPolarHBondContact OH-CA 3.08Å; Y115-D118 PolarHBondContact OH-OD1 3.45Å; Y115-D120 HydrophobicContact CD2-CB 3.66Å; Y115-D120 HydrophobicContact CE2-CB 3.85Å; Y115-D120 HydrophobicContact CG-CB 4.34Å; Y115-D123 HydrophobicContact CD2-CB 3.91Å; Y115-D123 HydrophobicContact CE2-CB 3.84Å; Y115-F262 HydrophobicContact CE2-CE2 4.29Å; Y115-F262 VanDerWaalsContact OH-CZ 3.26Å; Y115-F262 WeakPolarHBondContact OH-CZ 3.46Å
116R82Confident88.7Confident171 Ų17140.3 Ų40.365%0.64519%0.192SC*.  trans-120.8-23.2-172.5-58177.7-168.8-166.50.9114.4E114 D120E114-R116 WeakPolarHBondContact O-CG 3.09Å; E114-R116 IonicContact OE2-NH2 3.9Å; E114-R116 PolarHBondContact OE2-NH2 2.85Å; R116-D120 PolarHBondContact N-OD2 3.46Å
117K77.3Confident89.2Confident100 Ų10036.7 Ų36.744%0.43518%0.175SC..SBendtrans-158.1165.7-172.260.9171.9-174.9175.10110.3Y115 D120 E215Y115-K117 WeakPolarHBondContact CE2-O 3.19Å; Y115-K117 PolarHBondContact OH-O 2.97Å; K117-D120 HydrophobicContact CG-CB 4.22Å; K117-D120 WeakPolarHBondContact O-CB 3.45Å; K117-D120 PolarHBondContact O-N 3.22Å; K117-E215 WeakPolarHBondContact CE-OE2 3.46Å; K117-E215 IonicContact NZ-OE1 2.61Å; K117-E215 IonicContact NZ-OE2 3.21Å; K117-E215 PolarHBondContact NZ-OE2 3.13Å
118D67.6Low89.3Confident70 Ų7037 Ų3737%0.37418%0.176SC..THydrogen-bonded Turntrans-58.5143.4173-57.2-33.6000111.4S77 Y115 D120 F262S77-D118 PolarHBondContact OG-OD2 2.61Å; Y115-D118 WeakPolarHBondContact OH-CA 3.08Å; Y115-D118 PolarHBondContact OH-OD1 3.45Å; D118-D120 PolarHBondContact O-N 2.93Å; D118-F262 HydrophobicContact CB-CE1 4.32Å; D118-F262 HydrophobicContact CB-CZ 4.17Å
119F70Confident89.4Confident84 Ų8435.3 Ų35.337%0.36817%0.167SC..THydrogen-bonded Turntrans673.9-173.4-43.2-78.8000117.2F262F119-F262 HydrophobicContact CD1-CB 3.56Å; F119-F262 AromaticContact CD1-CD1 3.8Å; F119-F262 HydrophobicContact CD1-CD1 3.8Å; F119-F262 AromaticContact CD1-CD2 3.99Å; F119-F262 HydrophobicContact CD1-CD2 3.99Å; F119-F262 AromaticContact CD1-CG 3.48Å; F119-F262 HydrophobicContact CD1-CG 3.48Å; F119-F262 VanDerWaalsContact CD1-CG 3.48Å; F119-F262 HydrophobicContact CE1-CB 3.72Å; F119-F262 AromaticContact CE1-CD1 3.61Å; F119-F262 HydrophobicContact CE1-CD1 3.61Å; F119-F262 HydrophobicContact CE1-CE1 4.43Å; F119-F262 AromaticContact CE1-CG 3.73Å; F119-F262 HydrophobicContact CE1-CG 3.73Å; F119-F262 HydrophobicContact CG-CG 4.37Å; F119-F262 HydrophobicContact CZ-CD1 4.29Å; F119-F262 VanDerWaalsContact N-CE2 3.31Å
120D79.5Confident89.2Confident15 Ų1535.5 Ų35.58%0.0817%0.167CC..  trans-58135.5175.3-175.8-38.2000111.8Y115 R116 K117 D118 N122 D123Y115-D120 HydrophobicContact CD2-CB 3.66Å; Y115-D120 HydrophobicContact CE2-CB 3.85Å; Y115-D120 HydrophobicContact CG-CB 4.34Å; R116-D120 PolarHBondContact N-OD2 3.46Å; K117-D120 HydrophobicContact CG-CB 4.22Å; K117-D120 WeakPolarHBondContact O-CB 3.45Å; K117-D120 PolarHBondContact O-N 3.22Å; D118-D120 PolarHBondContact O-N 2.93Å; D120-N122 PolarHBondContact O-N 3.23Å; D120-N122 VanDerWaalsContact O-N 3.16Å; D120-N122 WeakPolarHBondContact OD1-CB 3.39Å; D120-N122 PolarHBondContact OD1-N 3.01Å; D120-N122 PolarHBondContact OD1-ND2 2.94Å; D120-D123 WeakPolarHBondContact O-CB 3.25Å; D120-D123 PolarHBondContact O-N 2.77Å
121A86.8Confident89.1Confident12 Ų1235.2 Ų35.210%0.09917%0.167CC..THydrogen-bonded Turntrans-67-13.2-175.900000114.9D123 D217 K220 Q221A121-D123 PolarHBondContact O-N 3.2Å; A121-D217 HydrophobicContact CB-CB 3.54Å; A121-K220 HydrophobicContact CB-CB 4.12Å; A121-K220 HydrophobicContact CB-CD 4.05Å; A121-Q221 HydrophobicContact CB-CG 4.12Å
122N91.8Very high89Confident30 Ų3034.7 Ų34.716%0.1616%0.162CC..THydrogen-bonded Turntrans-90.730.9176.9-49.6-78.8000112.2D120 I124 K220D120-N122 PolarHBondContact O-N 3.23Å; D120-N122 VanDerWaalsContact O-N 3.16Å; D120-N122 WeakPolarHBondContact OD1-CB 3.39Å; D120-N122 PolarHBondContact OD1-N 3.01Å; D120-N122 PolarHBondContact OD1-ND2 2.94Å; N122-I124 VanDerWaalsContact C-N 3.28Å; N122-I124 PolarHBondContact O-N 3.33Å; N122-K220 PolarHBondContact OD1-NZ 3.11Å
123D92Very high89Confident0 Ų033.2 Ų33.20%016%0.155CC..  trans-72.775.1-177.2-170.822.4000112.8A70 A71 H72 Y115 D120 A121 S261 T277A70-D123 WeakPolarHBondContact CB-OD1 3.41Å; A71-D123 WeakPolarHBondContact CA-OD1 3.43Å; A71-D123 WeakPolarHBondContact CB-OD1 3.41Å; A71-D123 PolarHBondContact N-OD1 3.14Å; H72-D123 IonicContact CE1-OD2 3.09Å; H72-D123 IonicContact CG-OD1 2.67Å; H72-D123 IonicContact CG-OD2 3.06Å; H72-D123 PolarHBondContact N-OD1 2.04Å; H72-D123 IonicContact ND1-OD1 3.62Å; H72-D123 PolarHBondContact ND1-OD1 2.83Å; H72-D123 IonicContact ND1-OD2 3.97Å; H72-D123 PolarHBondContact ND1-OD2 2.9Å; Y115-D123 HydrophobicContact CD2-CB 3.91Å; Y115-D123 HydrophobicContact CE2-CB 3.84Å; D120-D123 WeakPolarHBondContact O-CB 3.25Å; D120-D123 PolarHBondContact O-N 2.77Å; A121-D123 PolarHBondContact O-N 3.2Å; D123-S261 WeakPolarHBondContact OD2-CA 3.49Å; D123-S261 VanDerWaalsContact OD2-CB 3.24Å; D123-S261 WeakPolarHBondContact OD2-CB 3.48Å; D123-S261 PolarHBondContact OD2-OG 2.92Å; D123-T277 WeakPolarHBondContact O-CB 3.45Å; D123-T277 PolarHBondContact O-OG1 3.06Å
124I95.4Very high89Confident0 Ų033.5 Ų33.50%016%0.155CC..  trans-145.3139.7179-173.9172.1000110.9L68 G113 N122 I259 T277 L279 F282 W285 I286L68-I124 HydrophobicContact CD1-CD1 3.81Å; L68-I124 HydrophobicContact CD1-CG1 3.77Å; G113-I124 PolarHBondContact N-O 3.48Å; N122-I124 VanDerWaalsContact C-N 3.28Å; N122-I124 PolarHBondContact O-N 3.33Å; I124-I259 HydrophobicContact CB-CD1 4.2Å; I124-I259 HydrophobicContact CD1-CD1 4.01Å; I124-I259 HydrophobicContact CG1-CD1 3.67Å; I124-T277 HydrophobicContact CB-CG2 4.44Å; I124-L279 HydrophobicContact CD1-CD1 4.08Å; I124-F282 HydrophobicContact CD1-CB 3.46Å; I124-F282 VanDerWaalsContact CD1-CB 3.46Å; I124-F282 HydrophobicContact CD1-CD1 4.31Å; I124-F282 HydrophobicContact CD1-CD2 4.47Å; I124-F282 HydrophobicContact CD1-CG 3.85Å; I124-F282 HydrophobicContact CG2-CD1 3.7Å; I124-F282 HydrophobicContact CG2-CE1 3.89Å; I124-F282 HydrophobicContact CG2-CG 4.22Å; I124-W285 HydrophobicContact CB-CZ3 4.5Å; I124-W285 HydrophobicContact CD1-CE3 3.91Å; I124-W285 HydrophobicContact CD1-CZ3 3.67Å; I124-W285 HydrophobicContact CG1-CE3 4.42Å; I124-W285 HydrophobicContact CG1-CH2 4.42Å; I124-W285 HydrophobicContact CG1-CZ3 3.75Å; I124-W285 HydrophobicContact CG2-CE3 4.27Å; I124-W285 HydrophobicContact CG2-CH2 4.3Å; I124-W285 HydrophobicContact CG2-CZ3 4.01Å; I124-I286 HydrophobicContact CD1-CD1 4.21Å; I124-I286 HydrophobicContact CD1-CG1 4.27Å
125A96.7Very high89.1Confident0 Ų027.7 Ų27.70%013%0.128CC..EExtended strand (participates in β ladder)trans-140.3155.1171.600000112.6T69 I74 A111T69-A125 HydrophobicContact CG2-CB 4.01Å; T69-A125 PolarHBondContact N-O 3.12Å; T69-A125 PolarHBondContact O-N 2.95Å; I74-A125 HydrophobicContact CD1-CB 3.48Å; I74-A125 VanDerWaalsContact CD1-CB 3.48Å; I74-A125 HydrophobicContact CG1-CB 3.79Å; A111-A125 CarbonylContact O-C 3.6Å; A111-A125 VanDerWaalsContact O-CA 3.26Å; A111-A125 WeakPolarHBondContact O-CA 3.31Å
126L97.6Very high89.2Confident0 Ų028.1 Ų28.10%013%0.131CC..EExtended strand (participates in β ladder)trans-121.2136172.3-64.6170.1000109.4I56 M66 V67 L68 V110 A111 W285 I286 M289 M293I56-L126 HydrophobicContact CD1-CD2 3.92Å; M66-L126 HydrophobicContact CG-CD2 4.04Å; M66-L126 HydrophobicContact SD-CB 4.4Å; M66-L126 HydrophobicContact SD-CD1 3.99Å; M66-L126 HydrophobicContact SD-CD2 3.9Å; M66-L126 HydrophobicContact SD-CG 4.32Å; V67-L126 WeakPolarHBondContact O-CA 3.21Å; L68-L126 HydrophobicContact CB-CD2 4.4Å; L68-L126 HydrophobicContact CD1-CD2 3.72Å; V110-L126 WeakPolarHBondContact CA-O 3.42Å; A111-L126 HydrophobicContact CB-CB 4.44Å; A111-L126 PolarHBondContact N-O 2.89Å; A111-L126 PolarHBondContact O-N 2.98Å; L126-W285 HydrophobicContact CD1-CE3 4.42Å; L126-W285 HydrophobicContact CD1-CH2 3.87Å; L126-W285 HydrophobicContact CD1-CZ3 3.69Å; L126-W285 HydrophobicContact CG-CH2 3.86Å; L126-W285 HydrophobicContact CG-CZ3 3.75Å; L126-I286 HydrophobicContact CD1-CB 4.24Å; L126-I286 HydrophobicContact CD1-CG1 4.25Å; L126-I286 HydrophobicContact CD1-CG2 3.95Å; L126-I286 HydrophobicContact CD2-CG1 4.28Å; L126-I286 HydrophobicContact CD2-CG2 4.06Å; L126-M289 HydrophobicContact CD1-CB 3.79Å; L126-M289 HydrophobicContact CD1-CG 4.45Å; L126-M293 HydrophobicContact CB-CE 4.29Å; L126-M293 HydrophobicContact CB-SD 3.99Å; L126-M293 HydrophobicContact CD1-SD 4.47Å
127L97.7Very high89.3Confident0 Ų022.8 Ų22.80%012%0.115CC..EExtended strand (participates in β ladder)trans-114.9123.5173.6-41.3178.2000108.1I37 M66 V67 T69 I74 I88 V90 V107 V110I37-L127 HydrophobicContact CD1-CD1 3.85Å; I37-L127 HydrophobicContact CG2-CD1 4.2Å; M66-L127 WeakPolarHBondContact CA-O 3.47Å; V67-L127 HydrophobicContact CB-CB 4.23Å; V67-L127 HydrophobicContact CB-CD1 4.48Å; V67-L127 HydrophobicContact CG1-CD1 4.23Å; V67-L127 PolarHBondContact N-O 2.86Å; V67-L127 PolarHBondContact O-N 3.06Å; T69-L127 HydrophobicContact CG2-CD1 4.15Å; T69-L127 HydrophobicContact CG2-CD2 4.27Å; T69-L127 HydrophobicContact CG2-CG 4.1Å; I74-L127 HydrophobicContact CD1-CD2 4.27Å; I74-L127 HydrophobicContact CG2-CD2 3.85Å; I88-L127 HydrophobicContact CG2-CD1 4.05Å; V90-L127 HydrophobicContact CG2-CD1 4.07Å; V107-L127 HydrophobicContact CG1-CB 3.89Å; V107-L127 HydrophobicContact CG2-CB 3.95Å; V107-L127 HydrophobicContact CG2-CD1 4.14Å; V110-L127 HydrophobicContact CB-CD2 4.44Å; V110-L127 HydrophobicContact CG1-CD2 3.65Å
128R97.4Very high89.7Confident8 Ų820.1 Ų20.13%0.0310%0.103CC..EExtended strand (participates in β ladder)trans-83.1123.8167.1-177.875.976-155.8-2.4108.3N65 V107 I108 D109 D290 M293 L294N65-R128 PolarHBondContact ND2-NH1 2.88Å; N65-R128 WeakPolarHBondContact O-CD 3.44Å; N65-R128 PolarHBondContact OD1-NH1 3.44Å; V107-R128 CarbonylContact C-O 3.53Å; V107-R128 WeakPolarHBondContact CA-O 3.44Å; V107-R128 WeakPolarHBondContact CG1-O 3.44Å; I108-R128 HydrophobicContact CG2-CB 3.86Å; I108-R128 HydrophobicContact CG2-CG 3.48Å; I108-R128 VanDerWaalsContact CG2-CG 3.48Å; I108-R128 PolarHBondContact N-O 3.07Å; D109-R128 HydrophobicContact CB-CB 4.13Å; D109-R128 PolarHBondContact O-N 2.74Å; R128-D290 IonicContact CZ-OD1 3.57Å; R128-D290 VanDerWaalsContact CZ-OD1 3.24Å; R128-D290 IonicContact NH1-OD1 2.82Å; R128-D290 PolarHBondContact NH1-OD1 3.01Å; R128-D290 PolarHBondContact NH2-O 2.79Å; R128-D290 IonicContact NH2-OD1 2.75Å; R128-D290 PolarHBondContact NH2-OD1 3.4Å; R128-M293 HydrophobicContact CB-CE 3.86Å; R128-L294 WeakPolarHBondContact CG-O 3.36Å; R128-L294 PolarHBondContact NE-O 2.72Å
129L96.4Very high90.8Very high0 Ų016.8 Ų16.80%09%0.085CC..EExtended strand (participates in β ladder)trans-74.4140.1173.7-57.9-178.9000110.2L55 N65 V67 V90 I105 S131 V133 S296L55-L129 HydrophobicContact CD2-CD1 4.18Å; N65-L129 PolarHBondContact O-N 3.39Å; V67-L129 HydrophobicContact CG2-CD1 4.18Å; V67-L129 HydrophobicContact CG2-CD2 3.98Å; V67-L129 HydrophobicContact CG2-CG 4.25Å; V90-L129 HydrophobicContact CB-CD2 3.82Å; V90-L129 HydrophobicContact CG1-CD2 4.2Å; V90-L129 HydrophobicContact CG2-CD2 3.68Å; I105-L129 HydrophobicContact CD1-CD1 4.28Å; I105-L129 HydrophobicContact CG2-CB 4.06Å; I105-L129 HydrophobicContact CG2-CD2 4.45Å; L129-S131 WeakPolarHBondContact CB-O 3.16Å; L129-S131 PolarHBondContact O-N 3.2Å; L129-V133 HydrophobicContact CD1-CG2 3.56Å; L129-S296 WeakPolarHBondContact O-CB 3.49Å; L129-S296 PolarHBondContact O-OG 3.06Å
130M93.4Very high92Very high41 Ų4113 Ų1320%0.2027%0.069CC..EExtended strand (participates in β ladder)trans-60.7-37.3176.7-171.8172.7-55.600111.7Q106 I108 S296 K297Q106-M130 HydrophobicContact CB-CE 4.19Å; Q106-M130 HydrophobicContact CG-CE 4.3Å; Q106-M130 VanDerWaalsContact O-CB 3.28Å; Q106-M130 WeakPolarHBondContact O-CB 3.44Å; Q106-M130 PolarHBondContact O-N 3.19Å; Q106-M130 VanDerWaalsContact OE1-CE 3.25Å; I108-M130 HydrophobicContact CB-CB 4.26Å; M130-S296 WeakPolarHBondContact O-CB 3.07Å; M130-K297 HydrophobicContact CG-CD 3.87Å; M130-K297 HydrophobicContact CG-CG 4.25Å; M130-K297 PolarHBondContact O-N 2.87Å; M130-K297 HydrophobicContact SD-CD 4.08Å
131S93.4Very high92.7Very high18 Ų1812.3 Ų12.313%0.1267%0.065CC..EExtended strand (participates in β ladder)trans-118.5136.1176.3-54.20000110.3L129 D298L129-S131 WeakPolarHBondContact CB-O 3.16Å; L129-S131 PolarHBondContact O-N 3.2Å; S131-D298 CarbonylContact C-O 3.57Å; S131-D298 WeakPolarHBondContact CA-O 3.45Å; S131-D298 WeakPolarHBondContact CA-OD1 3.23Å; S131-D298 WeakPolarHBondContact CB-OD1 3.12Å; S131-D298 PolarHBondContact OG-OD1 2.79Å
132G93.9Very high93.2Very high0 Ų011.8 Ų11.80%06%0.061CC..EExtended strand (participates in β ladder)trans-67139172.700000112.7P134 D298 L300G132-P134 WeakPolarHBondContact O-CD 3.44Å; G132-D298 PolarHBondContact N-O 3.33Å; G132-L300 PolarHBondContact O-N 3.25Å
133V93.9Very high93.4Very high0 Ų010.9 Ų10.90%06%0.057CC..EExtended strand (participates in β ladder)trans-89.2112.9177.7-1790000109.1L55 I63 S64 V92 I105 L129 T139 I305L55-V133 HydrophobicContact CD1-CG1 4.14Å; L55-V133 HydrophobicContact CD2-CG2 4.17Å; I63-V133 CarbonylContact C-O 3.54Å; I63-V133 VanDerWaalsContact CA-O 3.28Å; I63-V133 WeakPolarHBondContact CA-O 3.4Å; S64-V133 PolarHBondContact N-O 3.09Å; S64-V133 WeakPolarHBondContact O-CB 3.42Å; S64-V133 PolarHBondContact O-N 2.81Å; V92-V133 HydrophobicContact CG1-CG2 4.01Å; V92-V133 HydrophobicContact CG2-CG1 4.32Å; V92-V133 HydrophobicContact CG2-CG2 4.42Å; I105-V133 HydrophobicContact CD1-CG2 3.45Å; I105-V133 VanDerWaalsContact CD1-CG2 3.45Å; L129-V133 HydrophobicContact CD1-CG2 3.56Å; V133-T139 HydrophobicContact CG1-CG2 3.89Å; V133-I305 HydrophobicContact CG1-CD1 4.08Å
134P91.7Very high93.6Very high14 Ų1412.5 Ų12.59%0.0917%0.065CC..EExtended strand (participates in β ladder)trans-65.7148.8174.429.9-37.5000111G132 T139 L300 A302 I305G132-P134 WeakPolarHBondContact O-CD 3.44Å; P134-T139 PolarHBondContact O-OG1 2.82Å; P134-L300 WeakPolarHBondContact CD-O 3.38Å; P134-L300 WeakPolarHBondContact CG-O 3.26Å; P134-A302 HydrophobicContact CG-CB 4.3Å; P134-I305 HydrophobicContact CG-CD1 4.33Å; P134-I305 HydrophobicContact CG-CG1 3.99Å
135Y91.6Very high93.6Very high12 Ų1212.9 Ų12.95%0.0477%0.068CC..  trans-77130.6174.1-58.3-22.6000111.3F4 R57 G61 N62 I63 S64 T139 P141F4-Y135 HydrophobicContact CB-CD2 3.61Å; F4-Y135 HydrophobicContact CB-CG 4.06Å; F4-Y135 HydrophobicContact CD2-CD2 4.43Å; F4-Y135 HydrophobicContact CG-CD2 4.24Å; F4-Y135 HydrophobicContact CG-CG 4.34Å; R57-Y135 WeakPolarHBondContact CB-OH 3.45Å; G61-Y135 VanDerWaalsContact O-CE2 3.25Å; G61-Y135 WeakPolarHBondContact O-CE2 3.38Å; N62-Y135 HydrophobicContact CB-CD2 4.38Å; N62-Y135 PolarHBondContact O-N 3.08Å; I63-Y135 VanDerWaalsContact C-CE1 3.41Å; I63-Y135 PolarHBondContact O-OH 3.37Å; S64-Y135 PolarHBondContact N-OH 2.87Å; S64-Y135 VanDerWaalsContact OG-CE1 3.23Å; S64-Y135 WeakPolarHBondContact OG-CE1 3.35Å; S64-Y135 PolarHBondContact OG-OH 2.95Å; Y135-T139 WeakPolarHBondContact CA-O 3.4Å; Y135-P141 HydrophobicContact CE1-CG 3.88Å; Y135-P141 HydrophobicContact CE2-CG 4.28Å
136T87.4Confident93.4Very high16 Ų1618 Ų1810%0.09810%0.095CC..BIsolated β-bridgetrans-139.2177.7179.9720000108.6Y138 T139 V140 A302 I305T136-Y138 PolarHBondContact O-N 2.93Å; T136-Y138 PolarHBondContact OG1-N 3.31Å; T136-Y138 VanDerWaalsContact OG1-N 3.09Å; T136-T139 PolarHBondContact N-O 2.83Å; T136-T139 PolarHBondContact N-OG1 2.97Å; T136-T139 PolarHBondContact O-N 2.85Å; T136-T139 PolarHBondContact OG1-N 3.41Å; T136-T139 VanDerWaalsContact OG1-N 3.16Å; T136-T139 PolarHBondContact OG1-OG1 2.79Å; T136-V140 VanDerWaalsContact O-CG2 3.26Å; T136-V140 WeakPolarHBondContact O-CG2 3.35Å; T136-A302 HydrophobicContact CG2-CB 4.23Å; T136-I305 HydrophobicContact CG2-CB 4.38Å; T136-I305 HydrophobicContact CG2-CG1 4.16Å
137D84.5Confident93.3Very high58 Ų5824.1 Ų24.131%0.3112%0.118SC..THydrogen-bonded Turntrans-53.6-23.6169.4-67.5-23.5000113.9K10 F11K10-D137 HydrophobicContact CD-CB 3.72Å; K10-D137 WeakPolarHBondContact CD-OD1 3.14Å; K10-D137 IonicContact NZ-OD1 3.09Å; K10-D137 PolarHBondContact NZ-OD1 2.81Å; K10-D137 IonicContact NZ-OD2 3.66Å; K10-D137 PolarHBondContact NZ-OD2 2.87Å; F11-D137 HydrophobicContact CE2-CB 4.09Å
138Y86.2Confident93.1Very high44 Ų4434.9 Ų34.917%0.17316%0.159CC..THydrogen-bonded Turntrans-109.9-12.4-172.8-43.2-55.5000113.7F11 H29 P32 T136F11-Y138 AromaticContact CE2-CD1 3.64Å; F11-Y138 HydrophobicContact CE2-CD1 3.64Å; F11-Y138 AromaticContact CE2-CE1 3.55Å; F11-Y138 HydrophobicContact CE2-CE1 3.55Å; F11-Y138 HydrophobicContact CZ-CD1 4.19Å; F11-Y138 AromaticContact CZ-CE1 3.61Å; F11-Y138 HydrophobicContact CZ-CE1 3.61Å; H29-Y138 HydrophobicContact CB-CD1 3.84Å; H29-Y138 AromaticContact CD2-CD1 3.45Å; H29-Y138 VanDerWaalsContact CD2-CD1 3.45Å; H29-Y138 WeakPolarHBondContact CD2-CD1 3.29Å; H29-Y138 AromaticContact CD2-CE1 3.6Å; H29-Y138 AromaticContact CE1-CD1 3.92Å; H29-Y138 AromaticContact CG-CD1 3.33Å; H29-Y138 AromaticContact CG-CE1 3.99Å; H29-Y138 AromaticContact ND1-CD1 3.64Å; H29-Y138 AromaticContact NE2-CD1 3.84Å; H29-Y138 AromaticContact NE2-CE1 3.94Å; P32-Y138 WeakPolarHBondContact CA-O 3.4Å; P32-Y138 VanDerWaalsContact CB-C 3.48Å; P32-Y138 VanDerWaalsContact CB-O 3.25Å; P32-Y138 WeakPolarHBondContact CB-O 3.48Å; T136-Y138 PolarHBondContact O-N 2.93Å; T136-Y138 PolarHBondContact OG1-N 3.31Å; T136-Y138 VanDerWaalsContact OG1-N 3.09Å
139T90.8Very high92.9Very high0 Ų035.5 Ų35.50%017%0.165CC..BIsolated β-bridgetrans-135.4101.8-176.246.50000110.2P32 V92 V133 P134 Y135 T136 I305P32-T139 WeakPolarHBondContact O-CA 3.07Å; V92-T139 HydrophobicContact CB-CG2 4.4Å; V92-T139 HydrophobicContact CG2-CG2 4.41Å; V133-T139 HydrophobicContact CG1-CG2 3.89Å; P134-T139 PolarHBondContact O-OG1 2.82Å; Y135-T139 WeakPolarHBondContact CA-O 3.4Å; T136-T139 PolarHBondContact N-O 2.83Å; T136-T139 PolarHBondContact N-OG1 2.97Å; T136-T139 PolarHBondContact O-N 2.85Å; T136-T139 PolarHBondContact OG1-N 3.41Å; T136-T139 VanDerWaalsContact OG1-N 3.16Å; T136-T139 PolarHBondContact OG1-OG1 2.79Å; T139-I305 HydrophobicContact CG2-CG2 3.66Å
140V93.1Very high92.7Very high6 Ų646.1 Ų46.14%0.03621%0.205CC..  trans-143.7130.6-179.6-1790000107.3F4 P5 P32 W33 T136F4-V140 HydrophobicContact CD1-CG2 4.4Å; P5-V140 WeakPolarHBondContact O-CG1 3.46Å; P32-V140 CarbonylContact C-O 3.51Å; P32-V140 VanDerWaalsContact C-O 3.31Å; P32-V140 HydrophobicContact CB-CB 4.22Å; P32-V140 HydrophobicContact CB-CG2 4.47Å; P32-V140 HydrophobicContact CG-CB 3.92Å; P32-V140 HydrophobicContact CG-CG2 4.39Å; P32-V140 PolarHBondContact O-N 3.02Å; P32-V140 VanDerWaalsContact O-N 3.12Å; W33-V140 VanDerWaalsContact CA-O 3.29Å; W33-V140 WeakPolarHBondContact CA-O 3.48Å; W33-V140 WeakPolarHBondContact CB-O 3.02Å; W33-V140 PolarHBondContact N-O 2.02Å; W33-V140 VanDerWaalsContact N-O 3.16Å; T136-V140 VanDerWaalsContact O-CG2 3.26Å; T136-V140 WeakPolarHBondContact O-CG2 3.35Å
141P95.9Very high92.6Very high0 Ų046.1 Ų46.10%021%0.206CC..PPolyproline II helixtrans-71.7152.7-175.829.6-35.9000111.6C6 G7 L55 R57 Y135C6-P141 CarbonylContact C-O 3.52Å; C6-P141 VanDerWaalsContact CA-O 3.28Å; C6-P141 WeakPolarHBondContact CA-O 3.27Å; C6-P141 HydrophobicContact CB-CG 4.38Å; C6-P141 WeakPolarHBondContact CB-O 3.47Å; G7-P141 PolarHBondContact N-O 3.47Å; L55-P141 HydrophobicContact CB-CB 4.4Å; L55-P141 WeakPolarHBondContact O-CA 3.06Å; L55-P141 VanDerWaalsContact O-CB 3.31Å; L55-P141 WeakPolarHBondContact O-CB 3.35Å; R57-P141 HydrophobicContact CB-CB 4.35Å; R57-P141 HydrophobicContact CB-CG 4.07Å; R57-P141 HydrophobicContact CG-CB 4.35Å; R57-P141 HydrophobicContact CG-CG 3.85Å; Y135-P141 HydrophobicContact CE1-CG 3.88Å; Y135-P141 HydrophobicContact CE2-CG 4.28Å
142V96.6Very high92.5Very high1 Ų145.5 Ų45.51%0.00620%0.201CC..BIsolated β-bridgetrans-73.5151.2169.368.80000109.7W33 L55 I56 V247 F254 Q256W33-V142 HydrophobicContact CB-CB 3.92Å; W33-V142 HydrophobicContact CB-CG1 4.47Å; W33-V142 HydrophobicContact CD2-CB 3.93Å; W33-V142 HydrophobicContact CD2-CG2 4.32Å; W33-V142 HydrophobicContact CE3-CB 4.35Å; W33-V142 HydrophobicContact CG-CB 3.72Å; W33-V142 HydrophobicContact CG-CG2 4.46Å; L55-V142 PolarHBondContact O-N 2.91Å; I56-V142 HydrophobicContact CG2-CG1 3.97Å; V142-V247 HydrophobicContact CG2-CG1 3.76Å; V142-F254 HydrophobicContact CG2-CB 4.5Å; V142-F254 WeakPolarHBondContact CG2-O 3.33Å; V142-Q256 HydrophobicContact CG1-CB 3.89Å; V142-Q256 HydrophobicContact CG2-CB 3.93Å
143C96Very high92.4Very high10 Ų1048.9 Ų48.97%0.06822%0.222CC..BIsolated β-bridgetrans-73.4135.5171.7-64.60000110.5C6 F254 I255 Q256C6-C143 HydrophobicContact CB-CB 4.02Å; C6-C143 WeakPolarHBondContact CB-SG 3.33Å; C6-C143 PolarHBondContact O-SG 2.91Å; C6-C143 WeakPolarHBondContact SG-CA 3.39Å; C6-C143 WeakPolarHBondContact SG-CB 3.45Å; C6-C143 CovalentContact SG-SG 2.05Å; C6-C143 PolarHBondContact SG-SG 2.77Å; C143-F254 PolarHBondContact N-O 3.46Å; C143-I255 HydrophobicContact CB-CG1 4.21Å; C143-I255 WeakPolarHBondContact O-CA 3.31Å; C143-Q256 PolarHBondContact O-N 3.16Å
144L95.8Very high92.1Very high35 Ų3552.3 Ų52.318%0.18326%0.257CS..PPolyproline II helixtrans-73.4150.8164.2-68.3175.3000110.1I56 L58 L68 L279 I286I56-L144 HydrophobicContact CB-CD2 4.36Å; I56-L144 HydrophobicContact CB-CG 4.49Å; I56-L144 HydrophobicContact CD1-CD1 4.42Å; I56-L144 HydrophobicContact CD1-CD2 4.4Å; I56-L144 HydrophobicContact CG2-CD2 3.95Å; I56-L144 HydrophobicContact CG2-CG 4.48Å; L58-L144 HydrophobicContact CD2-CD1 3.54Å; L68-L144 HydrophobicContact CD2-CD2 4.39Å; L144-L279 HydrophobicContact CD2-CD2 3.84Å; L144-I286 HydrophobicContact CD2-CD1 4.43Å
145P95.4Very high92Very high8 Ų855.8 Ų55.85%0.05227%0.271CS..PPolyproline II helixtrans-80162.5178.734.1-32.3000110.9A149 I255 Q256 Y257 L279 P280 V283P145-A149 HydrophobicContact CB-CB 4.16Å; P145-I255 HydrophobicContact CB-CG2 3.79Å; P145-Q256 WeakPolarHBondContact CD-O 3.48Å; P145-Q256 WeakPolarHBondContact CG-O 3.47Å; P145-Y257 HydrophobicContact CB-CD1 4.39Å; P145-Y257 HydrophobicContact CB-CE1 4.29Å; P145-L279 HydrophobicContact CG-CB 4.27Å; P145-L279 HydrophobicContact CG-CD2 4.44Å; P145-L279 HydrophobicContact CG-CG 4.17Å; P145-P280 HydrophobicContact CB-CG 3.95Å; P145-P280 HydrophobicContact CG-CB 4.36Å; P145-P280 HydrophobicContact CG-CG 3.71Å; P145-V283 HydrophobicContact CG-CG2 4.09Å
146D93.5Very high91.7Very high106 Ų10662.5 Ų62.557%0.56730%0.3SS*.PPolyproline II helixtrans-64.4146.1167.7-177.4-93.7000110.6R148 A149D146-R148 PolarHBondContact O-N 2.93Å; D146-R148 VanDerWaalsContact O-N 3.08Å; D146-R148 WeakPolarHBondContact OD1-CA 3.38Å; D146-R148 VanDerWaalsContact OD1-CB 3.29Å; D146-R148 WeakPolarHBondContact OD1-CB 3.41Å; D146-R148 PolarHBondContact OD1-N 2.61Å; D146-A149 HydrophobicContact CB-CB 4.29Å; D146-A149 WeakPolarHBondContact O-CB 3.15Å; D146-A149 PolarHBondContact O-N 3.18Å
147R94.1Very high91.8Very high129 Ų12961.9 Ų61.949%0.48730%0.296SS..THydrogen-bonded Turntrans-58.8-22.2179.5-68.2174.5174.5-158.68.9113.8V283 E287R147-V283 HydrophobicContact CG-CB 3.92Å; R147-V283 HydrophobicContact CG-CG1 3.85Å; R147-E287 IonicContact CZ-OE1 3.82Å; R147-E287 VanDerWaalsContact CZ-OE1 3.28Å; R147-E287 IonicContact CZ-OE2 3.28Å; R147-E287 IonicContact NE-OE1 2.65Å; R147-E287 PolarHBondContact NE-OE1 2.85Å; R147-E287 IonicContact NH2-OE1 3.86Å; R147-E287 PolarHBondContact NH2-OE1 2.84Å; R147-E287 IonicContact NH2-OE2 3.24Å; R147-E287 PolarHBondContact NH2-OE2 3.38Å
148R94.1Very high91.9Very high227 Ų22761.2 Ų61.286%0.85729%0.29SS*.THydrogen-bonded Turntrans-1077.3178.4-52.6178.5179.4-179.50.3112.4D146 R150D146-R148 PolarHBondContact O-N 2.93Å; D146-R148 VanDerWaalsContact O-N 3.08Å; D146-R148 WeakPolarHBondContact OD1-CA 3.38Å; D146-R148 VanDerWaalsContact OD1-CB 3.29Å; D146-R148 WeakPolarHBondContact OD1-CB 3.41Å; D146-R148 PolarHBondContact OD1-N 2.61Å; R148-R150 PolarHBondContact O-N 2.9Å
149A93.1Very high91.8Very high20 Ų2059.7 Ų59.717%0.16529%0.285CS..PPolyproline II helixtrans-58.4136.9177.600000110.5P145 D146 Y257 F278 P280P145-A149 HydrophobicContact CB-CB 4.16Å; D146-A149 HydrophobicContact CB-CB 4.29Å; D146-A149 WeakPolarHBondContact O-CB 3.15Å; D146-A149 PolarHBondContact O-N 3.18Å; A149-Y257 HydrophobicContact CB-CE1 3.83Å; A149-F278 WeakPolarHBondContact O-CZ 3.43Å; A149-P280 HydrophobicContact CB-CB 4.42Å; A149-P280 HydrophobicContact CB-CG 4.1Å
150R93Very high91.5Very high224 Ų22459.8 Ų59.885%0.84529%0.286SS*.PPolyproline II helixtrans-86.7165179-65.6-177.7179.2178.4-1110.2R148 Y257R148-R150 PolarHBondContact O-N 2.9Å; R150-Y257 WeakPolarHBondContact O-CE1 3.21Å
151L91.8Very high90.9Very high41 Ų4159.6 Ų59.622%0.21529%0.285CS..PPolyproline II helixtrans-57.9125.1175.7-168.968.6000110.4V153 V200 I201 I203 F222 F278L151-V153 HydrophobicContact CB-CG2 4.31Å; L151-V153 HydrophobicContact CD2-CG2 3.75Å; L151-V153 HydrophobicContact CG-CG2 3.89Å; L151-V153 PolarHBondContact O-N 3.05Å; L151-V200 HydrophobicContact CD1-CG1 3.58Å; L151-V200 HydrophobicContact CD2-CG1 4.05Å; L151-V200 HydrophobicContact CG-CG1 3.55Å; L151-I201 WeakPolarHBondContact CD2-O 3.48Å; L151-I203 HydrophobicContact CD2-CG1 4.4Å; L151-F222 HydrophobicContact CD1-CB 3.46Å; L151-F222 VanDerWaalsContact CD1-CB 3.46Å; L151-F222 HydrophobicContact CD1-CD1 4.15Å; L151-F222 HydrophobicContact CD1-CD2 3.66Å; L151-F222 HydrophobicContact CD1-CE2 4.38Å; L151-F222 HydrophobicContact CD1-CG 3.5Å; L151-F222 VanDerWaalsContact CD1-CG 3.5Å; L151-F222 HydrophobicContact CD2-CB 4.47Å; L151-F278 HydrophobicContact CD1-CD2 4.13Å; L151-F278 HydrophobicContact CD1-CE2 3.94Å
152P91.3Very high89.9Confident4 Ų459.6 Ų59.63%0.02629%0.285CS..  trans-81.350.4-171.235.3-39.8000112.5G154 K155 V200 C248 Y257P152-G154 PolarHBondContact O-N 2.92Å; P152-K155 HydrophobicContact CB-CB 4.05Å; P152-K155 HydrophobicContact CB-CG 3.65Å; P152-K155 WeakPolarHBondContact O-CB 3.35Å; P152-K155 WeakPolarHBondContact O-CG 3.3Å; P152-K155 PolarHBondContact O-N 2.77Å; P152-K155 VanDerWaalsContact O-N 3.11Å; P152-V200 HydrophobicContact CG-CB 4.48Å; P152-V200 HydrophobicContact CG-CG1 4.4Å; P152-V200 HydrophobicContact CG-CG2 4.12Å; P152-C248 HydrophobicContact CB-CB 4.42Å; P152-C248 VanDerWaalsContact CG-SG 3.51Å; P152-Y257 HydrophobicContact CB-CD1 4.41Å; P152-Y257 HydrophobicContact CB-CD2 4.15Å; P152-Y257 HydrophobicContact CB-CE1 4.27Å; P152-Y257 HydrophobicContact CB-CE2 3.99Å; P152-Y257 HydrophobicContact CB-CG 4.32Å; P152-Y257 HydrophobicContact CG-CD1 3.83Å; P152-Y257 HydrophobicContact CG-CD2 3.83Å; P152-Y257 HydrophobicContact CG-CE1 4.18Å; P152-Y257 HydrophobicContact CG-CE2 4.16Å; P152-Y257 HydrophobicContact CG-CG 3.61Å
153V90.9Very high88.1Confident72 Ų7259.7 Ų59.744%0.43629%0.286SS..THydrogen-bonded Turntrans-58.2132178.3-178.20000109.8L151 K155 V200L151-V153 HydrophobicContact CB-CG2 4.31Å; L151-V153 HydrophobicContact CD2-CG2 3.75Å; L151-V153 HydrophobicContact CG-CG2 3.89Å; L151-V153 PolarHBondContact O-N 3.05Å; V153-K155 PolarHBondContact O-N 3.14Å; V153-V200 HydrophobicContact CG2-CG1 4.37Å
154G86.6Confident85.8Confident72 Ų7259.6 Ų59.674%0.74229%0.285SS*.THydrogen-bonded Turntrans73.22-178.300000115.7P152P152-G154 PolarHBondContact O-N 2.92Å
155K89.7Confident83.3Confident87 Ų8761.6 Ų61.638%0.37830%0.295SS..SBendtrans-77.5154.8169.8-56.2-67.9176.5150.10110.1P152 V153 C157 C248 E250P152-K155 HydrophobicContact CB-CB 4.05Å; P152-K155 HydrophobicContact CB-CG 3.65Å; P152-K155 WeakPolarHBondContact O-CB 3.35Å; P152-K155 WeakPolarHBondContact O-CG 3.3Å; P152-K155 PolarHBondContact O-N 2.77Å; P152-K155 VanDerWaalsContact O-N 3.11Å; V153-K155 PolarHBondContact O-N 3.14Å; K155-C157 PolarHBondContact O-N 2.81Å; K155-C157 VanDerWaalsContact O-N 3.14Å; K155-C248 HydrophobicContact CB-CB 4.4Å; K155-E250 HydrophobicContact CD-CG 4.15Å; K155-E250 WeakPolarHBondContact CE-OE2 3.1Å; K155-E250 HydrophobicContact CG-CG 4.44Å; K155-E250 IonicContact NZ-OE2 2.74Å; K155-E250 PolarHBondContact NZ-OE2 2.87Å
156K86.8Confident80.4Confident153 Ų15363.4 Ų63.467%0.66531%0.308SS*.  trans-74.1103.3170.1-68.4-172.7179.6-176.20108.5Y158 C248 H249K156-Y158 HydrophobicContact CB-CE2 4.33Å; K156-C248 WeakPolarHBondContact O-CA 3.36Å; K156-H249 PolarHBondContact O-N 3.28Å
157C88.1Confident77.5Confident2 Ų260.1 Ų60.11%0.01430%0.299CS..EExtended strand (participates in β ladder)trans-115.3157.6177.5-52.10000111K155 I198 V200 L246 V247 C248K155-C157 PolarHBondContact O-N 2.81Å; K155-C157 VanDerWaalsContact O-N 3.14Å; C157-I198 HydrophobicContact CB-CG2 3.96Å; C157-I198 WeakPolarHBondContact CB-O 3.06Å; C157-I198 PolarHBondContact O-N 2.8Å; C157-V200 HydrophobicContact CB-CG2 4.3Å; C157-L246 HydrophobicContact CB-CD2 3.89Å; C157-V247 CarbonylContact C-O 3.5Å; C157-V247 WeakPolarHBondContact CA-O 3.12Å; C157-C248 HydrophobicContact CB-CB 4.06Å; C157-C248 WeakPolarHBondContact CB-SG 3.45Å; C157-C248 WeakPolarHBondContact SG-CB 3.19Å; C157-C248 CovalentContact SG-SG 2.04Å; C157-C248 PolarHBondContact SG-SG 2.9Å
158Y86.3Confident74.4Confident44 Ų4460.6 Ų60.617%0.17331%0.309CS..EExtended strand (participates in β ladder)trans-144.1152.2-176.6-52.9-90000110.5L13 W24 K156 M195 V196 D197 L246 V247 F254L13-Y158 HydrophobicContact CD1-CD2 4.21Å; L13-Y158 HydrophobicContact CD1-CE2 3.98Å; W24-Y158 HydrophobicContact CH2-CD1 4.2Å; W24-Y158 HydrophobicContact CH2-CE1 4.17Å; W24-Y158 HydrophobicContact CZ2-CD1 4.25Å; W24-Y158 HydrophobicContact CZ2-CE1 4.19Å; K156-Y158 HydrophobicContact CB-CE2 4.33Å; Y158-M195 HydrophobicContact CD1-CE 3.71Å; Y158-M195 HydrophobicContact CD2-CE 3.99Å; Y158-M195 HydrophobicContact CG-CE 3.4Å; Y158-V196 WeakPolarHBondContact CA-O 3.25Å; Y158-D197 HydrophobicContact CD1-CB 4.2Å; Y158-D197 HydrophobicContact CE1-CB 4.2Å; Y158-L246 WeakPolarHBondContact O-CA 3.4Å; Y158-V247 PolarHBondContact N-O 3.18Å; Y158-V247 PolarHBondContact O-N 3.04Å; Y158-F254 HydrophobicContact CD2-CE1 4.11Å; Y158-F254 HydrophobicContact CE2-CE1 4.1Å
159V85.3Confident71.4Confident12 Ų1257.1 Ų57.17%0.07330%0.3CS..EExtended strand (participates in β ladder)trans-121.7142.9169.9171.40000108.1M195 V196 I198 L246 V260 Y276V159-M195 WeakPolarHBondContact O-CA 3.41Å; V159-V196 HydrophobicContact CB-CG1 4.2Å; V159-V196 PolarHBondContact N-O 3.13Å; V159-V196 PolarHBondContact O-N 2.05Å; V159-I198 HydrophobicContact CG2-CD1 4.17Å; V159-I198 HydrophobicContact CG2-CG2 4.08Å; V159-L246 HydrophobicContact CG2-CB 3.88Å; V159-L246 HydrophobicContact CG2-CD1 4.04Å; V159-L246 HydrophobicContact CG2-CG 3.9Å; V159-V260 HydrophobicContact CG1-CG2 3.64Å; V159-Y276 HydrophobicContact CG2-CE1 3.85Å
160S84.7Confident68.5Low3 Ų360.1 Ų60.12%0.02131%0.313CS..EExtended strand (participates in β ladder)trans-129.6148175.360.80000112.2H34 M194H34-S160 PolarHBondContact ND1-OG 2.82Å; S160-M194 WeakPolarHBondContact CA-O 3.47Å; S160-M194 WeakPolarHBondContact CB-O 3.28Å
161G79.5Confident65.6Low1 Ų153.7 Ų53.71%0.0130%0.295CS..EExtended strand (participates in β ladder)trans-172.3162.6-174.300000113.6M194 D241G161-M194 PolarHBondContact N-O 2.72Å; G161-M194 PolarHBondContact O-N 2.8Å; G161-D241 WeakPolarHBondContact CA-OD1 3.19Å
162H75.2Confident62.6Low1 Ų159.6 Ų59.61%0.00533%0.326CS..SBendtrans-102.121.9167.8-67.895.8000110.3H34 H95 V97 P190 K192 L193H34-H162 AromaticContact NE2-CE1 3.77Å; H34-H162 AromaticContact NE2-ND1 3.41Å; H34-H162 PolarHBondContact NE2-ND1 3.47Å; H95-H162 PolarHBondContact O-NE2 2.76Å; V97-H162 HydrophobicContact CG1-CB 4.46Å; H162-P190 WeakPolarHBondContact O-CD 3.35Å; H162-K192 VanDerWaalsContact CD2-C 3.4Å; H162-L193 PolarHBondContact CD2-N 3.2Å; H162-L193 WeakPolarHBondContact NE2-CA 3.43Å; H162-L193 PolarHBondContact NE2-N 3.05Å
163G59Low59.9Low3 Ų364.8 Ų64.83%0.03135%0.352CS..  trans-80.7154-178.700000114.4I165 P190 Q239 G240 D241G163-I165 PolarHBondContact O-N 2.03Å; G163-P190 VanDerWaalsContact C-CD 3.45Å; G163-P190 WeakPolarHBondContact O-CD 3.49Å; G163-P190 WeakPolarHBondContact O-CG 3.19Å; G163-Q239 WeakPolarHBondContact CA-O 3.47Å; G163-G240 VanDerWaalsContact CA-C 3.49Å; G163-D241 WeakPolarHBondContact CA-OD1 3.33Å; G163-D241 PolarHBondContact N-OD1 2.93Å
164S47Very low57.1Low7 Ų766.2 Ų66.25%0.04936%0.357CS..  trans-60.7122.5-167.9-174.10000112.5S166 L188 I238 Q239S164-S166 PolarHBondContact O-N 3.25Å; S164-L188 WeakPolarHBondContact CB-O 3.41Å; S164-L188 PolarHBondContact OG-O 3.18Å; S164-I238 WeakPolarHBondContact O-CD1 3.15Å; S164-I238 VanDerWaalsContact O-CG2 3.31Å; S164-I238 WeakPolarHBondContact O-CG2 3.36Å; S164-Q239 PolarHBondContact N-O 3.26Å
165I44.8Very low54.7Low77 Ų7772 Ų7240%0.39537%0.365SS..SBendtrans-65.14.2176.357.6173.2000114.6G163 P190 M194G163-I165 PolarHBondContact O-N 2.03Å; I165-P190 HydrophobicContact CG2-CB 4.3Å; I165-P190 HydrophobicContact CG2-CG 4.14Å; I165-M194 HydrophobicContact CG2-CE 4.23Å; I165-M194 HydrophobicContact CG2-CG 4Å
166S33.8Very low52.1Low46 Ų4675 Ų7532%0.32238%0.384SS..  trans-110.680.5-175.5-151.40000114.5S164 M168 K169S164-S166 PolarHBondContact O-N 3.25Å; S166-M168 PolarHBondContact O-N 2.86Å; S166-M168 VanDerWaalsContact O-N 3.13Å; S166-K169 WeakPolarHBondContact OG-CB 3.22Å; S166-K169 PolarHBondContact OG-N 3.13Å
167G33.6Very low49.6Very low37 Ų3773.6 Ų73.638%0.38139%0.388SS..SBendtrans-61-11.3161.900000114.5
168M28.7Very low46.9Very low140 Ų14079.3 Ų79.369%0.6942%0.423SS*.SBendtrans-112.9-17.4-170.6-77.7-179.1-77.800116.6S166 L170 L171S166-M168 PolarHBondContact O-N 2.86Å; S166-M168 VanDerWaalsContact O-N 3.13Å; M168-L170 PolarHBondContact O-N 3.24Å; M168-L171 HydrophobicContact CG-CD1 4.3Å; M168-L171 WeakPolarHBondContact O-CB 3Å; M168-L171 PolarHBondContact O-N 2.92Å
169K30.5Very low44.3Very low154 Ų15488.5 Ų88.567%0.6746%0.457SS*.G310 helixtrans-69.4-15.4-175.1-129.7176.3-177.8-179.80115S166 L171S166-K169 WeakPolarHBondContact OG-CB 3.22Å; S166-K169 PolarHBondContact OG-N 3.13Å; K169-L171 VanDerWaalsContact C-N 3.32Å
170L32.7Very low41.8Very low83 Ų8397.6 Ų97.644%0.43550%0.497SS..G310 helixtrans-79.7-11.3177.7-149.873.7000113.5M168 L172 I267M168-L170 PolarHBondContact O-N 3.24Å; L170-L172 VanDerWaalsContact C-N 3.27Å; L170-L172 PolarHBondContact O-N 3.2Å; L170-I267 HydrophobicContact CD2-CD1 4.42Å; L170-I267 HydrophobicContact CG-CD1 4.46Å
171L31.5Very low39.2Very low89 Ų89105 Ų10547%0.46653%0.528SS..G310 helixtrans-77.51.1-173.6-82.4160.4000115.5M168 K169 I267M168-L171 HydrophobicContact CG-CD1 4.3Å; M168-L171 WeakPolarHBondContact O-CB 3Å; M168-L171 PolarHBondContact O-N 2.92Å; K169-L171 VanDerWaalsContact C-N 3.32Å; L171-I267 HydrophobicContact CD2-CD1 4.43Å; L171-I267 HydrophobicContact CD2-CG2 3.67Å
172L29.1Very low36.8Very low164 Ų164109.9 Ų109.986%0.85956%0.562SS**G310 helixtrans-125.6-0.2-172.3-93.4161000115.7L170L170-L172 VanDerWaalsContact C-N 3.27Å; L170-L172 PolarHBondContact O-N 3.2Å
173I33.5Very low34.6Very low113 Ų113117.8 Ų117.858%0.57960%0.604SS**THydrogen-bonded Turntrans-112.1-21.1-172-57.9-179.8000112.9Q175I173-Q175 PolarHBondContact O-N 2.76Å
174N33Very low33.1Very low102 Ų102122.3 Ų122.355%0.54564%0.641SS.*THydrogen-bonded Turntrans-81.123.5-174.6-75.35.3000115.8
175Q35.6Very low32.3Very low193 Ų193127 Ų12790%0.90267%0.669SS**THydrogen-bonded Turntrans-115.25.9171-82.6-166.3-18.900114.3I173I173-Q175 PolarHBondContact O-N 2.76Å
176I34.7Very low31.6Very low152 Ų152128 Ų12878%0.77969%0.69SS**SBendtrans-111.7126.2174.7-58.1-178.7000110T178I176-T178 PolarHBondContact O-N 2.81Å
177T34.5Very low31.8Very low122 Ų122128.7 Ų128.775%0.74870%0.698SS**  trans-59.4125.5-171.545.40000114.2R179T177-R179 PolarHBondContact O-N 3.28Å
178T32.4Very low32.4Very low123 Ų123131.7 Ų131.776%0.75571%0.705SS**SBendtrans1596.3143.8550000117.7I176I176-T178 PolarHBondContact O-N 2.81Å
179R32Very low33.5Very low236 Ų236127.7 Ų127.789%0.89169%0.686SS**SBendtrans178-7.4134.9-100.3172.2-173.3-145.90.8116.8T177T177-R179 PolarHBondContact O-N 3.28Å
180F31.2Very low34.6Very low204 Ų204121.1 Ų121.190%0.89566%0.659SS**  trans-108.529.4-176.4-77.5-84.9000115.3S182F180-S182 PolarHBondContact O-N 2.91Å
181F31Very low36.6Very low157 Ų157120.3 Ų120.369%0.68965%0.653SS**THydrogen-bonded Turntrans-86.111.1-159.3-139.9-95.6000117
182S28.5Very low38.8Very low104 Ų104120 Ų12073%0.72765%0.648SS**THydrogen-bonded Turntrans-110.44.6-165.664.40000118.1F180F180-S182 PolarHBondContact O-N 2.91Å
183L29.7Very low41.3Very low168 Ų168112.4 Ų112.488%0.8861%0.608SS**SBendtrans-132.8-0.7-176.1-98.597.2000117.5
184A28.2Very low43.5Very low97 Ų97108.7 Ų108.780%0.80259%0.589SS**  trans-113.98.2-165.400000116.6
185T28.6Very low45.5Very low105 Ų105104 Ų10464%0.64456%0.564SS**  trans-104.825.4-167.953.60000115.7A187T185-A187 PolarHBondContact O-N 2.94Å
186A31.6Very low47.3Very low100 Ų10095.5 Ų95.583%0.82653%0.525SS*.  trans-76.473.7161.400000109.6L188A186-L188 PolarHBondContact O-N 2.87Å; A186-L188 VanDerWaalsContact O-N 3.15Å
187A37.7Very low49.1Very low60 Ų6089.6 Ų89.650%0.49650%0.495SS..  trans-63.8114.8176.400000109.5T185 L189T185-A187 PolarHBondContact O-N 2.94Å; A187-L189 PolarHBondContact O-N 2.97Å
188L46.2Very low51.2Low100 Ų10083.9 Ų83.952%0.52446%0.46SS..  trans-43.7107.9-175.7-72.5144.5000111.9S164 A186 T350S164-L188 WeakPolarHBondContact CB-O 3.41Å; S164-L188 PolarHBondContact OG-O 3.18Å; A186-L188 PolarHBondContact O-N 2.87Å; A186-L188 VanDerWaalsContact O-N 3.15Å; L188-T350 WeakPolarHBondContact CD2-O 3Å
189L51.1Low53.4Low55 Ų5580.1 Ų80.129%0.28844%0.435SS..  trans-78.6137.2169-60.9174.1000107.6Q50 A187 E191 Q239Q50-L189 VanDerWaalsContact CD-CD1 3.47Å; Q50-L189 HydrophobicContact CG-CD1 4.11Å; A187-L189 PolarHBondContact O-N 2.97Å; L189-E191 PolarHBondContact O-N 3.5Å; L189-Q239 WeakPolarHBondContact CD2-O 3.34Å
190P54.6Low56Low17 Ų1769.1 Ų69.111%0.1139%0.394CS..  trans-62127173.129.2-36.8000109.5H162 G163 I165 K192 M194H162-P190 WeakPolarHBondContact O-CD 3.35Å; G163-P190 VanDerWaalsContact C-CD 3.45Å; G163-P190 WeakPolarHBondContact O-CD 3.49Å; G163-P190 WeakPolarHBondContact O-CG 3.19Å; I165-P190 HydrophobicContact CG2-CB 4.3Å; I165-P190 HydrophobicContact CG2-CG 4.14Å; P190-K192 PolarHBondContact O-N 2.93Å; P190-M194 HydrophobicContact CB-CG 3.77Å; P190-M194 HydrophobicContact CB-SD 4.31Å; P190-M194 HydrophobicContact CG-CG 3.7Å
191E73.1Confident58.6Low65 Ų6560 Ų6030%0.30435%0.354SS..SBendtrans-61.6-29.4175.9-67.7169.8-166.400111.4D96 V97 T98 L189 T349D96-E191 CarbonylContact C-O 3.49Å; D96-E191 WeakPolarHBondContact CA-O 3.31Å; V97-E191 WeakPolarHBondContact CG2-O 3.46Å; V97-E191 PolarHBondContact N-O 2.75Å; T98-E191 HydrophobicContact CG2-CB 3.79Å; T98-E191 HydrophobicContact CG2-CG 3.57Å; L189-E191 PolarHBondContact O-N 3.5Å; E191-T349 WeakPolarHBondContact OE1-CB 2.92Å; E191-T349 WeakPolarHBondContact OE1-CG2 3.08Å; E191-T349 PolarHBondContact OE1-OG1 2.9Å; E191-T349 PolarHBondContact OE2-OG1 3Å
192K78.4Confident61.3Low82 Ų8254.2 Ų54.236%0.35733%0.334SS..BIsolated β-bridgetrans-104.6155.5-178.9-55.8-170-174.5179.30112.9E25 H95 H162 P190 M194E25-K192 HydrophobicContact CG-CB 4.3Å; E25-K192 HydrophobicContact CG-CD 4.07Å; E25-K192 WeakPolarHBondContact OE1-CD 3.31Å; E25-K192 IonicContact OE1-NZ 3.69Å; E25-K192 PolarHBondContact OE1-NZ 3.06Å; E25-K192 VanDerWaalsContact OE2-CD 3.27Å; E25-K192 WeakPolarHBondContact OE2-CD 3.48Å; E25-K192 IonicContact OE2-NZ 3.56Å; E25-K192 PolarHBondContact OE2-NZ 3.22Å; H95-K192 CarbonylContact O-C 3.57Å; H95-K192 WeakPolarHBondContact O-CA 3.19Å; H162-K192 VanDerWaalsContact CD2-C 3.4Å; P190-K192 PolarHBondContact O-N 2.93Å; K192-M194 PolarHBondContact O-N 3.49Å
193L81.7Confident64.2Low6 Ų652.1 Ų52.13%0.03131%0.314CS..  trans-66.5119.8179.3-178.154000110.6A26 L31 H34 H95 H162A26-L193 HydrophobicContact CB-CB 4.35Å; A26-L193 HydrophobicContact CB-CD2 4.26Å; A26-L193 HydrophobicContact CB-CG 3.98Å; A26-L193 WeakPolarHBondContact CB-O 3.27Å; A26-L193 PolarHBondContact N-O 3.06Å; L31-L193 HydrophobicContact CB-CD2 4.1Å; L31-L193 HydrophobicContact CD1-CD2 3.85Å; L31-L193 HydrophobicContact CD1-CG 4.27Å; H34-L193 HydrophobicContact CB-CD2 4.08Å; H34-L193 VanDerWaalsContact NE2-CD1 3.34Å; H34-L193 WeakPolarHBondContact NE2-CD1 3.1Å; H95-L193 PolarHBondContact O-N 3.1Å; H162-L193 PolarHBondContact CD2-N 3.2Å; H162-L193 WeakPolarHBondContact NE2-CA 3.43Å; H162-L193 PolarHBondContact NE2-N 3.05Å
194M79.5Confident67Low35 Ų3549.3 Ų49.317%0.17230%0.296CS..EExtended strand (participates in β ladder)trans-97.9153.8174.9-57.2-57.8-6700110.4G23 W24 E25 S160 G161 I165 P190 K192G23-M194 WeakPolarHBondContact O-CE 3.34Å; W24-M194 VanDerWaalsContact C-CE 3.41Å; W24-M194 CarbonylContact O-C 3.58Å; W24-M194 WeakPolarHBondContact O-CA 3.42Å; E25-M194 HydrophobicContact CB-SD 4.34Å; S160-M194 WeakPolarHBondContact CA-O 3.47Å; S160-M194 WeakPolarHBondContact CB-O 3.28Å; G161-M194 PolarHBondContact N-O 2.72Å; G161-M194 PolarHBondContact O-N 2.8Å; I165-M194 HydrophobicContact CG2-CE 4.23Å; I165-M194 HydrophobicContact CG2-CG 4Å; P190-M194 HydrophobicContact CB-CG 3.77Å; P190-M194 HydrophobicContact CB-SD 4.31Å; P190-M194 HydrophobicContact CG-CG 3.7Å; K192-M194 PolarHBondContact O-N 3.49Å
195M76Confident69.7Low3 Ų347.4 Ų47.42%0.01527%0.27CS..EExtended strand (participates in β ladder)trans-140.7143.6178.6-172.2174.9-166.300110.3L13 G23 W24 A26 L31 Y158 V159L13-M195 HydrophobicContact CD1-CE 3.53Å; L13-M195 HydrophobicContact CD1-SD 4.42Å; L13-M195 HydrophobicContact CD2-CE 3.66Å; L13-M195 HydrophobicContact CD2-SD 3.9Å; L13-M195 HydrophobicContact CG-CE 4.17Å; G23-M195 CarbonylContact C-O 3.6Å; G23-M195 WeakPolarHBondContact CA-O 3.4Å; W24-M195 HydrophobicContact CZ2-CG 4.34Å; W24-M195 PolarHBondContact N-O 3.2Å; W24-M195 PolarHBondContact O-N 3.18Å; A26-M195 HydrophobicContact CB-CB 4.17Å; L31-M195 HydrophobicContact CD1-CB 4.41Å; L31-M195 HydrophobicContact CD1-CE 4.46Å; L31-M195 HydrophobicContact CD1-CG 4.33Å; L31-M195 HydrophobicContact CD1-SD 3.88Å; L31-M195 HydrophobicContact CD2-CE 3.77Å; L31-M195 HydrophobicContact CD2-SD 4.13Å; L31-M195 HydrophobicContact CG-SD 4.27Å; Y158-M195 HydrophobicContact CD1-CE 3.71Å; Y158-M195 HydrophobicContact CD2-CE 3.99Å; Y158-M195 HydrophobicContact CG-CE 3.4Å; V159-M195 WeakPolarHBondContact O-CA 3.41Å
196V72.3Confident72.4Confident15 Ų1542.5 Ų42.59%0.09124%0.24CC..EExtended strand (participates in β ladder)trans-137.6143.9177.271.10000110.4Y158 V159 T226 T235Y158-V196 WeakPolarHBondContact CA-O 3.25Å; V159-V196 HydrophobicContact CB-CG1 4.2Å; V159-V196 PolarHBondContact N-O 3.13Å; V159-V196 PolarHBondContact O-N 2.05Å; V196-T226 HydrophobicContact CG2-CG2 4.1Å; V196-T235 HydrophobicContact CG1-CG2 4.22Å
197D73.8Confident74.9Confident28 Ų2844.8 Ų44.815%0.1523%0.228CC..EExtended strand (participates in β ladder)trans-71.3140.9166.970.1-51.3000109.9N18 W24 Y158N18-D197 PolarHBondContact ND2-OD2 3.21Å; N18-D197 VanDerWaalsContact OD1-CG 3.26Å; N18-D197 PolarHBondContact OD1-OD1 3.36Å; N18-D197 VanDerWaalsContact OD1-OD1 3.14Å; W24-D197 HydrophobicContact CH2-CB 3.93Å; W24-D197 VanDerWaalsContact CH2-N 3.29Å; W24-D197 HydrophobicContact CZ3-CB 4.3Å; Y158-D197 HydrophobicContact CD1-CB 4.2Å; Y158-D197 HydrophobicContact CE1-CB 4.2Å
198I77.5Confident77Confident2 Ų250.5 Ų50.51%0.0124%0.236CC..EExtended strand (participates in β ladder)trans-139.1140.3178.9-151.9172.8000110.8C157 V159 A224 G225 T235 L246 Y276C157-I198 HydrophobicContact CB-CG2 3.96Å; C157-I198 WeakPolarHBondContact CB-O 3.06Å; C157-I198 PolarHBondContact O-N 2.8Å; V159-I198 HydrophobicContact CG2-CD1 4.17Å; V159-I198 HydrophobicContact CG2-CG2 4.08Å; I198-A224 HydrophobicContact CD1-CB 3.55Å; I198-A224 HydrophobicContact CG1-CB 3.76Å; I198-A224 HydrophobicContact CG2-CB 4.4Å; I198-G225 WeakPolarHBondContact CG1-O 3.5Å; I198-T235 VanDerWaalsContact CD1-OG1 3.31Å; I198-T235 WeakPolarHBondContact CD1-OG1 3.44Å; I198-L246 HydrophobicContact CD1-CD1 4.49Å; I198-L246 HydrophobicContact CG2-CD1 3.71Å; I198-L246 HydrophobicContact CG2-CG 3.98Å; I198-Y276 HydrophobicContact CD1-CE2 4.05Å; I198-Y276 WeakPolarHBondContact CD1-OH 3.14Å
199N79.6Confident78.3Confident44 Ų4446.8 Ų46.824%0.23522%0.217CC..EExtended strand (participates in β ladder)trans-102.7119.5179.8-61.5-95.6000106.7I201 A224 G225 N227N199-I201 PolarHBondContact O-N 3.07Å; N199-A224 CarbonylContact O-C 3.55Å; N199-A224 VanDerWaalsContact O-CA 3.25Å; N199-A224 WeakPolarHBondContact O-CA 3.19Å; N199-A224 WeakPolarHBondContact O-CB 3.49Å; N199-G225 PolarHBondContact N-O 2.71Å; N199-G225 PolarHBondContact O-N 2.97Å; N199-N227 VanDerWaalsContact CG-CG 3.47Å; N199-N227 PolarHBondContact ND2-ND2 3.02Å; N199-N227 VanDerWaalsContact ND2-ND2 3.2Å; N199-N227 PolarHBondContact ND2-OD1 3.18Å; N199-N227 PolarHBondContact OD1-ND2 2.94Å
200V86.3Confident79.3Confident5 Ų545.6 Ų45.63%0.0321%0.21CC..EExtended strand (participates in β ladder)trans-73.1123.5173.5177.20000108.3L151 P152 V153 C157 F222 A224 L246L151-V200 HydrophobicContact CD1-CG1 3.58Å; L151-V200 HydrophobicContact CD2-CG1 4.05Å; L151-V200 HydrophobicContact CG-CG1 3.55Å; P152-V200 HydrophobicContact CG-CB 4.48Å; P152-V200 HydrophobicContact CG-CG1 4.4Å; P152-V200 HydrophobicContact CG-CG2 4.12Å; V153-V200 HydrophobicContact CG2-CG1 4.37Å; C157-V200 HydrophobicContact CB-CG2 4.3Å; V200-F222 HydrophobicContact CG1-CD2 3.79Å; V200-F222 HydrophobicContact CG1-CE2 3.96Å; V200-F222 HydrophobicContact CG2-CE2 3.94Å; V200-A224 HydrophobicContact CG2-CB 4.29Å; V200-L246 HydrophobicContact CG2-CD1 4.46Å; V200-L246 HydrophobicContact CG2-CD2 4.17Å
201I84.5Confident79.9Confident12 Ų1247.4 Ų47.46%0.06222%0.219CC..PPolyproline II helixtrans-89.2143.5-171.3-60.5162.3000108.4L151 N199 E205 C206 L209 C223 L232 A273L151-I201 WeakPolarHBondContact CD2-O 3.48Å; N199-I201 PolarHBondContact O-N 3.07Å; I201-E205 HydrophobicContact CG2-CB 3.58Å; I201-E205 HydrophobicContact CG2-CG 3.65Å; I201-C206 HydrophobicContact CG2-CB 4.29Å; I201-L209 HydrophobicContact CD1-CD1 4.12Å; I201-L209 HydrophobicContact CG2-CD1 4.37Å; I201-C223 HydrophobicContact CB-CB 3.98Å; I201-C223 HydrophobicContact CD1-CB 3.97Å; I201-C223 HydrophobicContact CG2-CB 4.48Å; I201-C223 PolarHBondContact N-O 3.28Å; I201-L232 HydrophobicContact CD1-CD2 3.48Å; I201-L232 VanDerWaalsContact CD1-CD2 3.48Å; I201-L232 HydrophobicContact CG1-CD2 4.03Å; I201-A273 HydrophobicContact CD1-CB 4.27Å
202S89.4Confident79.5Confident36 Ų3649 Ų4925%0.25224%0.243SC..PPolyproline II helixtrans-66.4162.1177.289.90000111.7E204 E205 C206S202-E204 VanDerWaalsContact C-N 3.26Å; S202-E204 WeakPolarHBondContact CB-OE2 3.27Å; S202-E204 PolarHBondContact O-N 3.05Å; S202-E204 PolarHBondContact OG-N 2.77Å; S202-E204 PolarHBondContact OG-OE2 3.43Å; S202-E205 PolarHBondContact O-N 2.91Å; S202-E205 PolarHBondContact OG-N 3.22Å; S202-C206 WeakPolarHBondContact O-CB 3.3Å; S202-C206 PolarHBondContact O-N 3.46Å
203I88.5Confident78.7Confident60 Ų6052.5 Ų52.531%0.30827%0.266SS..Hα-helixtrans-59.9-40.1179.7-70.2174.9000110.8L151 R207 F218L151-I203 HydrophobicContact CD2-CG1 4.4Å; I203-R207 VanDerWaalsContact CG2-CZ 3.42Å; I203-R207 WeakPolarHBondContact O-CB 3.36Å; I203-R207 VanDerWaalsContact O-CG 3.27Å; I203-R207 WeakPolarHBondContact O-CG 3.21Å; I203-R207 PolarHBondContact O-N 2.84Å; I203-F218 HydrophobicContact CB-CD1 4.29Å; I203-F218 HydrophobicContact CG1-CD1 4.16Å; I203-F218 HydrophobicContact CG2-CD1 3.7Å; I203-F218 HydrophobicContact CG2-CE1 4.01Å; I203-F218 HydrophobicContact CG2-CG 4.25Å
204E87.8Confident78Confident109 Ų10953.9 Ų53.951%0.50928%0.276SS..Hα-helixtrans-65.8-40.8-178-55.667.5-142.700111.8S202S202-E204 VanDerWaalsContact C-N 3.26Å; S202-E204 WeakPolarHBondContact CB-OE2 3.27Å; S202-E204 PolarHBondContact O-N 3.05Å; S202-E204 PolarHBondContact OG-N 2.77Å; S202-E204 PolarHBondContact OG-OE2 3.43Å
205E84.8Confident77.7Confident57 Ų5758 Ų5827%0.26630%0.295SS..Hα-helixtrans-79.2-38178.9-173.866.7-175.700111.2I201 S202 R207 R208 L209I201-E205 HydrophobicContact CG2-CB 3.58Å; I201-E205 HydrophobicContact CG2-CG 3.65Å; S202-E205 PolarHBondContact O-N 2.91Å; S202-E205 PolarHBondContact OG-N 3.22Å; E205-R207 VanDerWaalsContact C-N 3.29Å; E205-R207 PolarHBondContact O-N 2.84Å; E205-R208 WeakPolarHBondContact O-CB 3.45Å; E205-R208 PolarHBondContact O-N 2.82Å; E205-R208 WeakPolarHBondContact OE2-CD 3.33Å; E205-R208 IonicContact OE2-CZ 3.76Å; E205-R208 IonicContact OE2-NE 4Å; E205-R208 IonicContact OE2-NH1 2.76Å; E205-R208 PolarHBondContact OE2-NH1 2.76Å; E205-L209 HydrophobicContact CG-CD1 4.19Å; E205-L209 WeakPolarHBondContact O-CG 3.21Å; E205-L209 PolarHBondContact O-N 2.93Å
206C85.2Confident78Confident2 Ų259 Ų591%0.01430%0.3CS..Hα-helixtrans-55.9-42.9171.5-179.50000111.3I201 S202 R208 L209 I210 F218 C223I201-C206 HydrophobicContact CG2-CB 4.29Å; S202-C206 WeakPolarHBondContact O-CB 3.3Å; S202-C206 PolarHBondContact O-N 3.46Å; C206-R208 VanDerWaalsContact C-N 3.26Å; C206-R208 PolarHBondContact O-N 3.16Å; C206-L209 PolarHBondContact O-N 3.42Å; C206-L209 VanDerWaalsContact O-N 3.1Å; C206-I210 PolarHBondContact O-N 3.37Å; C206-F218 HydrophobicContact CB-CE1 3.91Å; C206-F218 WeakPolarHBondContact SG-CE1 3.32Å; C206-C223 VanDerWaalsContact CA-SG 3.57Å; C206-C223 HydrophobicContact CB-CB 3.51Å; C206-C223 WeakPolarHBondContact CB-SG 3.38Å; C206-C223 WeakPolarHBondContact SG-CB 3.14Å; C206-C223 CovalentContact SG-SG 2.02Å; C206-C223 PolarHBondContact SG-SG 2.7Å
207R85.6Confident78.8Confident147 Ų14760.8 Ų60.856%0.55531%0.309SS*.Hα-helixtrans-60-26.7174-78.3175.3-175.8155.31.7114.9I203 E205 F218I203-R207 VanDerWaalsContact CG2-CZ 3.42Å; I203-R207 WeakPolarHBondContact O-CB 3.36Å; I203-R207 VanDerWaalsContact O-CG 3.27Å; I203-R207 WeakPolarHBondContact O-CG 3.21Å; I203-R207 PolarHBondContact O-N 2.84Å; E205-R207 VanDerWaalsContact C-N 3.29Å; E205-R207 PolarHBondContact O-N 2.84Å; R207-F218 HydrophobicContact CB-CZ 4.26Å; R207-F218 HydrophobicContact CG-CE1 3.88Å; R207-F218 HydrophobicContact CG-CE2 3.66Å; R207-F218 HydrophobicContact CG-CZ 3.24Å
208R81.5Confident79.5Confident180 Ų18061.6 Ų61.668%0.67931%0.311SS*.Hα-helixtrans-84.4-20.8176.8-66170.6-178.9155.8-3.5112.9E205 C206E205-R208 WeakPolarHBondContact O-CB 3.45Å; E205-R208 PolarHBondContact O-N 2.82Å; E205-R208 WeakPolarHBondContact OE2-CD 3.33Å; E205-R208 IonicContact OE2-CZ 3.76Å; E205-R208 IonicContact OE2-NE 4Å; E205-R208 IonicContact OE2-NH1 2.76Å; E205-R208 PolarHBondContact OE2-NH1 2.76Å; C206-R208 VanDerWaalsContact C-N 3.26Å; C206-R208 PolarHBondContact O-N 3.16Å
209L73.8Confident80.2Confident22 Ų2267 Ų6712%0.11534%0.336CS..Hα-helixtrans-96.6-34.3-175-66172.8000112I201 E205 C206 L232 Q271 T272 A273I201-L209 HydrophobicContact CD1-CD1 4.12Å; I201-L209 HydrophobicContact CG2-CD1 4.37Å; E205-L209 HydrophobicContact CG-CD1 4.19Å; E205-L209 WeakPolarHBondContact O-CG 3.21Å; E205-L209 PolarHBondContact O-N 2.93Å; C206-L209 PolarHBondContact O-N 3.42Å; C206-L209 VanDerWaalsContact O-N 3.1Å; L209-L232 HydrophobicContact CD1-CD2 4.13Å; L209-Q271 WeakPolarHBondContact CB-O 3.29Å; L209-Q271 WeakPolarHBondContact CD2-O 3.43Å; L209-T272 VanDerWaalsContact O-CA 3.24Å; L209-T272 WeakPolarHBondContact O-CA 3.48Å; L209-A273 HydrophobicContact CB-CB 4Å; L209-A273 HydrophobicContact CD1-CB 4.27Å
210I70.8Confident80.8Confident30 Ų3067.9 Ų67.915%0.15434%0.338CS..SBendtrans-66.8145.1173.963.2176.2000111.4C206 F216 F218C206-I210 PolarHBondContact O-N 3.37Å; I210-F216 HydrophobicContact CD1-CB 3.85Å; I210-F216 HydrophobicContact CD1-CD1 4.44Å; I210-F216 HydrophobicContact CD1-CG 4.04Å; I210-F216 HydrophobicContact CG2-CD2 3.94Å; I210-F216 HydrophobicContact CG2-CE2 4.16Å; I210-F216 HydrophobicContact CG2-CG 4.45Å; I210-F218 HydrophobicContact CD1-CE2 3.92Å; I210-F218 HydrophobicContact CD1-CZ 3.72Å
211D67.2Low81Confident56 Ų5667.8 Ų67.830%0.29934%0.337SS..  trans-66.2143.8171.3-161.3-5.8000109.8D213 S214 Y269 T272D211-D213 VanDerWaalsContact C-N 3.25Å; D211-D213 PolarHBondContact O-N 3.27Å; D211-S214 VanDerWaalsContact O-CB 3.27Å; D211-S214 WeakPolarHBondContact O-CB 3.23Å; D211-S214 PolarHBondContact O-N 2.98Å; D211-Y269 HydrophobicContact CB-CE1 4.31Å; D211-Y269 WeakPolarHBondContact OD2-CE1 3.31Å; D211-Y269 PolarHBondContact OD2-OH 3.38Å; D211-T272 HydrophobicContact CB-CG2 4.29Å
212A64.7Low81.4Confident97 Ų9767.5 Ų67.580%0.80234%0.335SS*.THydrogen-bonded Turntrans-65.2-31.1-172.500000112.6S214A212-S214 VanDerWaalsContact C-N 3.3Å
213D63.4Low81.3Confident156 Ų15665.8 Ų65.883%0.83432%0.323SS*.THydrogen-bonded Turntrans-83.5-3.7178.1-64.1-31.3000113.2D211 E215D211-D213 VanDerWaalsContact C-N 3.25Å; D211-D213 PolarHBondContact O-N 3.27Å; D213-E215 PolarHBondContact O-N 2.78Å
214S66.7Low80.9Confident36 Ų3662.9 Ų62.925%0.25231%0.308SS..SBendtrans-79.2115178.8164.50000111.4D211 A212 F216 K275D211-S214 VanDerWaalsContact O-CB 3.27Å; D211-S214 WeakPolarHBondContact O-CB 3.23Å; D211-S214 PolarHBondContact O-N 2.98Å; A212-S214 VanDerWaalsContact C-N 3.3Å; S214-F216 PolarHBondContact O-N 2.89Å; S214-F216 VanDerWaalsContact O-N 3.15Å; S214-K275 PolarHBondContact OG-NZ 3.16Å
215E72.8Confident80.1Confident121 Ų12157.7 Ų57.757%0.56528%0.284SS*.  trans-52.7122163-163.4171.9175.200110.2K117 D213 K275K117-E215 WeakPolarHBondContact CE-OE2 3.46Å; K117-E215 IonicContact NZ-OE1 2.61Å; K117-E215 IonicContact NZ-OE2 3.21Å; K117-E215 PolarHBondContact NZ-OE2 3.13Å; D213-E215 PolarHBondContact O-N 2.78Å; E215-K275 PolarHBondContact O-NZ 2.87Å
216F81.1Confident78.9Confident25 Ų2555.3 Ų55.311%0.1127%0.273CS..  trans-152.5114.3-177.6-164.3-77.4000110.3I210 S214 F218 Q221 K275I210-F216 HydrophobicContact CD1-CB 3.85Å; I210-F216 HydrophobicContact CD1-CD1 4.44Å; I210-F216 HydrophobicContact CD1-CG 4.04Å; I210-F216 HydrophobicContact CG2-CD2 3.94Å; I210-F216 HydrophobicContact CG2-CE2 4.16Å; I210-F216 HydrophobicContact CG2-CG 4.45Å; S214-F216 PolarHBondContact O-N 2.89Å; S214-F216 VanDerWaalsContact O-N 3.15Å; F216-F218 HydrophobicContact CD1-CD1 4.03Å; F216-F218 AromaticContact CD1-CD2 3.8Å; F216-F218 HydrophobicContact CD1-CD2 3.8Å; F216-F218 AromaticContact CD1-CE1 3.91Å; F216-F218 HydrophobicContact CD1-CE1 3.91Å; F216-F218 AromaticContact CD1-CE2 3.64Å; F216-F218 HydrophobicContact CD1-CE2 3.64Å; F216-F218 AromaticContact CD1-CG 3.98Å; F216-F218 HydrophobicContact CD1-CG 3.98Å; F216-F218 AromaticContact CD1-CZ 3.68Å; F216-F218 HydrophobicContact CD1-CZ 3.68Å; F216-F218 AromaticContact CE1-CD1 3.71Å; F216-F218 HydrophobicContact CE1-CD1 3.71Å; F216-F218 HydrophobicContact CE1-CD2 4.33Å; F216-F218 AromaticContact CE1-CE1 3.66Å; F216-F218 HydrophobicContact CE1-CE1 3.66Å; F216-F218 HydrophobicContact CE1-CE2 4.25Å; F216-F218 HydrophobicContact CE1-CG 4.06Å; F216-F218 AromaticContact CE1-CZ 3.91Å; F216-F218 HydrophobicContact CE1-CZ 3.91Å; F216-F218 HydrophobicContact CG-CE2 4.45Å; F216-Q221 HydrophobicContact CD1-CB 4.3Å; F216-Q221 HydrophobicContact CE1-CB 3.78Å; F216-Q221 WeakPolarHBondContact CE1-O 3.38Å; F216-Q221 HydrophobicContact CE2-CB 4.13Å; F216-Q221 HydrophobicContact CZ-CB 3.69Å; F216-K275 HydrophobicContact CD2-CD 3.9Å; F216-K275 HydrophobicContact CD2-CG 4.29Å; F216-K275 HydrophobicContact CE2-CB 4.26Å; F216-K275 HydrophobicContact CE2-CD 3.98Å; F216-K275 HydrophobicContact CE2-CG 3.89Å
217D89.4Confident77.3Confident52 Ų5260 Ų6028%0.27830%0.299SS..  trans-97100.3-179.9-179.6-5.1000110.1A121 E219 K220 Q221A121-D217 HydrophobicContact CB-CB 3.54Å; D217-E219 PolarHBondContact O-N 2.97Å; D217-E219 VanDerWaalsContact O-N 3.11Å; D217-E219 WeakPolarHBondContact OD1-CB 3.39Å; D217-E219 PolarHBondContact OD1-N 3.06Å; D217-K220 HydrophobicContact CB-CB 4.36Å; D217-K220 CarbonylContact O-C 3.53Å; D217-K220 PolarHBondContact O-N 2.94Å; D217-K220 WeakPolarHBondContact OD2-CD 2.95Å; D217-K220 VanDerWaalsContact OD2-CE 3.29Å; D217-K220 WeakPolarHBondContact OD2-CE 3.49Å; D217-K220 WeakPolarHBondContact OD2-CG 3.32Å; D217-K220 IonicContact OD2-NZ 3.39Å; D217-Q221 WeakPolarHBondContact O-CA 3.42Å; D217-Q221 WeakPolarHBondContact O-CB 3.25Å; D217-Q221 PolarHBondContact O-N 2.96Å
218F89.5Confident75.3Confident45 Ų4553.9 Ų53.920%0.19728%0.278CS..THydrogen-bonded Turntrans-63.2-13.4179.9-74.7-84000115.2I203 C206 R207 I210 F216I203-F218 HydrophobicContact CB-CD1 4.29Å; I203-F218 HydrophobicContact CG1-CD1 4.16Å; I203-F218 HydrophobicContact CG2-CD1 3.7Å; I203-F218 HydrophobicContact CG2-CE1 4.01Å; I203-F218 HydrophobicContact CG2-CG 4.25Å; C206-F218 HydrophobicContact CB-CE1 3.91Å; C206-F218 WeakPolarHBondContact SG-CE1 3.32Å; R207-F218 HydrophobicContact CB-CZ 4.26Å; R207-F218 HydrophobicContact CG-CE1 3.88Å; R207-F218 HydrophobicContact CG-CE2 3.66Å; R207-F218 HydrophobicContact CG-CZ 3.24Å; I210-F218 HydrophobicContact CD1-CE2 3.92Å; I210-F218 HydrophobicContact CD1-CZ 3.72Å; F216-F218 HydrophobicContact CD1-CD1 4.03Å; F216-F218 AromaticContact CD1-CD2 3.8Å; F216-F218 HydrophobicContact CD1-CD2 3.8Å; F216-F218 AromaticContact CD1-CE1 3.91Å; F216-F218 HydrophobicContact CD1-CE1 3.91Å; F216-F218 AromaticContact CD1-CE2 3.64Å; F216-F218 HydrophobicContact CD1-CE2 3.64Å; F216-F218 AromaticContact CD1-CG 3.98Å; F216-F218 HydrophobicContact CD1-CG 3.98Å; F216-F218 AromaticContact CD1-CZ 3.68Å; F216-F218 HydrophobicContact CD1-CZ 3.68Å; F216-F218 AromaticContact CE1-CD1 3.71Å; F216-F218 HydrophobicContact CE1-CD1 3.71Å; F216-F218 HydrophobicContact CE1-CD2 4.33Å; F216-F218 AromaticContact CE1-CE1 3.66Å; F216-F218 HydrophobicContact CE1-CE1 3.66Å; F216-F218 HydrophobicContact CE1-CE2 4.25Å; F216-F218 HydrophobicContact CE1-CG 4.06Å; F216-F218 AromaticContact CE1-CZ 3.91Å; F216-F218 HydrophobicContact CE1-CZ 3.91Å; F216-F218 HydrophobicContact CG-CE2 4.45Å
219E91.2Very high73.2Confident115 Ų11555.4 Ų55.454%0.53729%0.289SS..THydrogen-bonded Turntrans-75.8-36.1169.6-75.2-74.5115.100110.9D217 K281D217-E219 PolarHBondContact O-N 2.97Å; D217-E219 VanDerWaalsContact O-N 3.11Å; D217-E219 WeakPolarHBondContact OD1-CB 3.39Å; D217-E219 PolarHBondContact OD1-N 3.06Å; E219-K281 VanDerWaalsContact O-CE 3.28Å; E219-K281 WeakPolarHBondContact O-CE 3.49Å; E219-K281 WeakPolarHBondContact O-CG 3.37Å; E219-K281 IonicContact OE1-NZ 3.73Å; E219-K281 WeakPolarHBondContact OE2-CE 3.17Å; E219-K281 IonicContact OE2-NZ 2.59Å; E219-K281 PolarHBondContact OE2-NZ 3.2Å
220K92.7Very high71.1Confident62 Ų6260.8 Ų60.827%0.2732%0.323SS..THydrogen-bonded Turntrans-110.5-10.9-171.5-62.8-179.3-164.1172.30115A121 N122 D217 F278 F282A121-K220 HydrophobicContact CB-CB 4.12Å; A121-K220 HydrophobicContact CB-CD 4.05Å; N122-K220 PolarHBondContact OD1-NZ 3.11Å; D217-K220 HydrophobicContact CB-CB 4.36Å; D217-K220 CarbonylContact O-C 3.53Å; D217-K220 PolarHBondContact O-N 2.94Å; D217-K220 WeakPolarHBondContact OD2-CD 2.95Å; D217-K220 VanDerWaalsContact OD2-CE 3.29Å; D217-K220 WeakPolarHBondContact OD2-CE 3.49Å; D217-K220 WeakPolarHBondContact OD2-CG 3.32Å; D217-K220 IonicContact OD2-NZ 3.39Å; K220-F278 WeakPolarHBondContact O-CB 3.41Å; K220-F278 PolarHBondContact O-N 2.9Å; K220-F282 HydrophobicContact CB-CE2 4.1Å; K220-F282 HydrophobicContact CB-CZ 4.03Å; K220-F282 HydrophobicContact CD-CZ 3.98Å; K220-F282 HydrophobicContact CG-CE2 4.38Å; K220-F282 HydrophobicContact CG-CZ 4.06Å
221Q91.6Very high69.2Low3 Ų362.2 Ų62.21%0.01434%0.34CS..EExtended strand (participates in β ladder)trans-134.2150.6-175.9-65.4173.9-48.300110.5A121 F216 D217 Y276A121-Q221 HydrophobicContact CB-CG 4.12Å; F216-Q221 HydrophobicContact CD1-CB 4.3Å; F216-Q221 HydrophobicContact CE1-CB 3.78Å; F216-Q221 WeakPolarHBondContact CE1-O 3.38Å; F216-Q221 HydrophobicContact CE2-CB 4.13Å; F216-Q221 HydrophobicContact CZ-CB 3.69Å; D217-Q221 WeakPolarHBondContact O-CA 3.42Å; D217-Q221 WeakPolarHBondContact O-CB 3.25Å; D217-Q221 PolarHBondContact O-N 2.96Å; Q221-Y276 CarbonylContact C-O 3.54Å; Q221-Y276 VanDerWaalsContact CA-O 3.25Å; Q221-Y276 WeakPolarHBondContact CA-O 3.38Å
222F91.7Very high67.5Low6 Ų662.5 Ų62.53%0.02634%0.341CS..EExtended strand (participates in β ladder)trans-144163.4174.371.5-84.8000112.4L151 V200 A224 L246 Y257 Y276 F278L151-F222 HydrophobicContact CD1-CB 3.46Å; L151-F222 VanDerWaalsContact CD1-CB 3.46Å; L151-F222 HydrophobicContact CD1-CD1 4.15Å; L151-F222 HydrophobicContact CD1-CD2 3.66Å; L151-F222 HydrophobicContact CD1-CE2 4.38Å; L151-F222 HydrophobicContact CD1-CG 3.5Å; L151-F222 VanDerWaalsContact CD1-CG 3.5Å; L151-F222 HydrophobicContact CD2-CB 4.47Å; V200-F222 HydrophobicContact CG1-CD2 3.79Å; V200-F222 HydrophobicContact CG1-CE2 3.96Å; V200-F222 HydrophobicContact CG2-CE2 3.94Å; F222-A224 HydrophobicContact CE2-CB 4.39Å; F222-L246 HydrophobicContact CE2-CD1 3.88Å; F222-L246 HydrophobicContact CE2-CD2 4.48Å; F222-L246 HydrophobicContact CZ-CD1 3.99Å; F222-L246 HydrophobicContact CZ-CD2 4.24Å; F222-Y257 WeakPolarHBondContact CE1-O 3.5Å; F222-Y276 WeakPolarHBondContact CD1-O 3.47Å; F222-Y276 VanDerWaalsContact CE1-CB 3.46Å; F222-Y276 HydrophobicContact CE2-CD2 4.32Å; F222-Y276 HydrophobicContact CE2-CG 4.16Å; F222-Y276 VanDerWaalsContact CZ-CB 3.49Å; F222-Y276 HydrophobicContact CZ-CG 4.08Å; F222-Y276 PolarHBondContact N-O 3.16Å; F222-Y276 PolarHBondContact O-N 2.88Å; F222-F278 HydrophobicContact CD1-CB 3.82Å; F222-F278 AromaticContact CD1-CD2 3.69Å; F222-F278 HydrophobicContact CD1-CD2 3.69Å; F222-F278 HydrophobicContact CD1-CG 4.17Å; F222-F278 HydrophobicContact CE1-CB 4.39Å; F222-F278 AromaticContact CE1-CD2 3.98Å; F222-F278 HydrophobicContact CE1-CD2 3.98Å; F222-F278 HydrophobicContact CG-CD2 4.46Å
223C87Confident66.3Low0 Ų062.8 Ų62.80%032%0.324CS..EExtended strand (participates in β ladder)trans-98.3143.4178.1-67.20000112.1I201 C206 A273 G274I201-C223 HydrophobicContact CB-CB 3.98Å; I201-C223 HydrophobicContact CD1-CB 3.97Å; I201-C223 HydrophobicContact CG2-CB 4.48Å; I201-C223 PolarHBondContact N-O 3.28Å; C206-C223 VanDerWaalsContact CA-SG 3.57Å; C206-C223 HydrophobicContact CB-CB 3.51Å; C206-C223 WeakPolarHBondContact CB-SG 3.38Å; C206-C223 WeakPolarHBondContact SG-CB 3.14Å; C206-C223 CovalentContact SG-SG 2.02Å; C206-C223 PolarHBondContact SG-SG 2.7Å; C223-A273 HydrophobicContact CB-CB 3.72Å; C223-A273 WeakPolarHBondContact SG-CB 3.25Å; C223-G274 WeakPolarHBondContact CA-O 3.39Å
224A81.1Confident65.2Low0 Ų057 Ų570%029%0.294CS..EExtended strand (participates in β ladder)trans-143.2156.9164.200000111.7I198 N199 V200 F222 L246 G274 Y276I198-A224 HydrophobicContact CD1-CB 3.55Å; I198-A224 HydrophobicContact CG1-CB 3.76Å; I198-A224 HydrophobicContact CG2-CB 4.4Å; N199-A224 CarbonylContact O-C 3.55Å; N199-A224 VanDerWaalsContact O-CA 3.25Å; N199-A224 WeakPolarHBondContact O-CA 3.19Å; N199-A224 WeakPolarHBondContact O-CB 3.49Å; V200-A224 HydrophobicContact CG2-CB 4.29Å; F222-A224 HydrophobicContact CE2-CB 4.39Å; A224-L246 HydrophobicContact CB-CD1 3.89Å; A224-G274 PolarHBondContact N-O 2.91Å; A224-Y276 HydrophobicContact CB-CD2 3.89Å; A224-Y276 HydrophobicContact CB-CE2 3.6Å
225G69.9Low64Low0 Ų056.6 Ų56.60%029%0.291CS..EExtended strand (participates in β ladder)trans-161.5172.4-177.200000114.7I198 N199I198-G225 WeakPolarHBondContact CG1-O 3.5Å; N199-G225 PolarHBondContact N-O 2.71Å; N199-G225 PolarHBondContact O-N 2.97Å
226T60.7Low62.6Low6 Ų654.6 Ų54.64%0.03728%0.278CS..BIsolated β-bridgetrans-94.4143.7-178.271.50000112.4V196 S228 K233 T235V196-T226 HydrophobicContact CG2-CG2 4.1Å; T226-S228 VanDerWaalsContact C-N 3.32Å; T226-S228 PolarHBondContact O-N 2.78Å; T226-K233 PolarHBondContact N-O 2.86Å; T226-K233 PolarHBondContact O-N 2.76Å; T226-K233 PolarHBondContact OG1-O 2.88Å; T226-T235 HydrophobicContact CG2-CG2 4.03Å
227N50.6Low60.8Low102 Ų10254.5 Ų54.555%0.54528%0.281SS..  trans-82.269.2179.2-75.9-13.2000112.1N199 K229N199-N227 VanDerWaalsContact CG-CG 3.47Å; N199-N227 PolarHBondContact ND2-ND2 3.02Å; N199-N227 VanDerWaalsContact ND2-ND2 3.2Å; N199-N227 PolarHBondContact ND2-OD1 3.18Å; N199-N227 PolarHBondContact OD1-ND2 2.94Å; N227-K229 PolarHBondContact O-N 2.94Å
228S44.7Very low58.9Low17 Ų1753.4 Ų53.412%0.11928%0.276CS..  trans-75.6120.3164.8-159.90000109.3T226 T230 A231T226-S228 VanDerWaalsContact C-N 3.32Å; T226-S228 PolarHBondContact O-N 2.78Å; S228-T230 PolarHBondContact O-N 1.89Å; S228-A231 CarbonylContact O-C 3.42Å; S228-A231 PolarHBondContact O-N 3.34Å
229K36.8Very low56.8Low212 Ų21257.3 Ų57.392%0.92229%0.294SS*.THydrogen-bonded Turntrans-68.925.4-168.7-75.5-170.1170.9-172.90116.8N227N227-K229 PolarHBondContact O-N 2.94Å
230T30.2Very low54.9Low135 Ų13551.9 Ų51.983%0.82827%0.269SS*.THydrogen-bonded Turntrans-142.2-9174.729.90000114.6S228S228-T230 PolarHBondContact O-N 1.89Å
231A30.7Very low53.6Low61 Ų6150.2 Ų50.250%0.50426%0.263SS..SBendtrans-169.8150168.800000107.7S228 K233S228-A231 CarbonylContact O-C 3.42Å; S228-A231 PolarHBondContact O-N 3.34Å; A231-K233 VanDerWaalsContact C-N 3.29Å; A231-K233 PolarHBondContact O-N 2.87Å
232L31.4Very low53Low62 Ų6251.1 Ų51.133%0.32527%0.27SS..  trans-6391.7172.6-133.5137.6000108.5I201 L209 V234I201-L232 HydrophobicContact CD1-CD2 3.48Å; I201-L232 VanDerWaalsContact CD1-CD2 3.48Å; I201-L232 HydrophobicContact CG1-CD2 4.03Å; L209-L232 HydrophobicContact CD1-CD2 4.13Å; L232-V234 PolarHBondContact O-N 2.9Å
233K39.3Very low52.7Low102 Ų10250.9 Ų50.944%0.44327%0.269SS..BIsolated β-bridgetrans-79.4100.2-178-82.2-166.7-173.41780107.9T226 A231 T235T226-K233 PolarHBondContact N-O 2.86Å; T226-K233 PolarHBondContact O-N 2.76Å; T226-K233 PolarHBondContact OG1-O 2.88Å; A231-K233 VanDerWaalsContact C-N 3.29Å; A231-K233 PolarHBondContact O-N 2.87Å; K233-T235 PolarHBondContact O-N 3.38Å
234V40.6Very low52.7Low34 Ų3450.9 Ų50.921%0.20627%0.269CS..  trans-60129176.7178.60000109.8L232 R236 T272 A273L232-V234 PolarHBondContact O-N 2.9Å; V234-R236 PolarHBondContact O-N 2.7Å; V234-T272 VanDerWaalsContact CG1-O 3.28Å; V234-T272 WeakPolarHBondContact CG1-O 3.34Å; V234-T272 WeakPolarHBondContact CG2-O 3.37Å; V234-A273 VanDerWaalsContact CG1-C 3.48Å; V234-A273 VanDerWaalsContact CG1-CA 3.5Å; V234-A273 HydrophobicContact CG2-CB 4.33Å
235T41.7Very low53.3Low29 Ų2950.9 Ų50.918%0.17827%0.269CS..  trans-67.1110.1167.6-15.80000108.1V196 I198 T226 K233 A237V196-T235 HydrophobicContact CG1-CG2 4.22Å; I198-T235 VanDerWaalsContact CD1-OG1 3.31Å; I198-T235 WeakPolarHBondContact CD1-OG1 3.44Å; T226-T235 HydrophobicContact CG2-CG2 4.03Å; K233-T235 PolarHBondContact O-N 3.38Å; T235-A237 PolarHBondContact O-N 3.36Å
236R43.2Very low54.4Low79 Ų7950.9 Ų50.930%0.29827%0.269SS..  trans-61.7124.7169.8-168.5178.8-165.3-158.96.7107.1V234 I238V234-R236 PolarHBondContact O-N 2.7Å; R236-I238 HydrophobicContact CB-CD1 4.14Å; R236-I238 HydrophobicContact CB-CG1 3.87Å; R236-I238 HydrophobicContact CG-CD1 4.35Å; R236-I238 HydrophobicContact CG-CG1 3.72Å; R236-I238 PolarHBondContact O-N 2.85Å
237A43.9Very low56Low22 Ų2250.7 Ų50.718%0.18227%0.268CS..  trans-68.7115.1161.900000106.4T235 V260T235-A237 PolarHBondContact O-N 3.36Å; A237-V260 HydrophobicContact CB-CG1 3.93Å
238I48.7Very low58.1Low30 Ų3045.9 Ų45.915%0.15424%0.242CC..  trans-107.9152.5-177.4-59.5168.9000108.1S164 R236 G240 D241S164-I238 WeakPolarHBondContact O-CD1 3.15Å; S164-I238 VanDerWaalsContact O-CG2 3.31Å; S164-I238 WeakPolarHBondContact O-CG2 3.36Å; R236-I238 HydrophobicContact CB-CD1 4.14Å; R236-I238 HydrophobicContact CB-CG1 3.87Å; R236-I238 HydrophobicContact CG-CD1 4.35Å; R236-I238 HydrophobicContact CG-CG1 3.72Å; R236-I238 PolarHBondContact O-N 2.85Å; I238-G240 PolarHBondContact O-N 3.25Å; I238-D241 WeakPolarHBondContact O-CB 3.07Å; I238-D241 PolarHBondContact O-N 2.84Å
239Q45.2Very low60.3Low127 Ų12749 Ų4959%0.59325%0.254SS*.THydrogen-bonded Turntrans-50.6125.6178-166.6169.713.500109.9G163 S164 L189G163-Q239 WeakPolarHBondContact CA-O 3.47Å; S164-Q239 PolarHBondContact N-O 3.26Å; L189-Q239 WeakPolarHBondContact CD2-O 3.34Å
240G51.9Low62.8Low1 Ų139.4 Ų39.41%0.0121%0.213CC..THydrogen-bonded Turntrans100.3-18.2-172.600000115.9G163 I238G163-G240 VanDerWaalsContact CA-C 3.49Å; I238-G240 PolarHBondContact O-N 3.25Å
241D65.5Low65.4Low27 Ų2743.5 Ų43.514%0.14421%0.213CC..THydrogen-bonded Turntrans-89.9-23.9171.9-59.4-41.2000112.6G161 G163 I238 G243 G244 V260G161-D241 WeakPolarHBondContact CA-OD1 3.19Å; G163-D241 WeakPolarHBondContact CA-OD1 3.33Å; G163-D241 PolarHBondContact N-OD1 2.93Å; I238-D241 WeakPolarHBondContact O-CB 3.07Å; I238-D241 PolarHBondContact O-N 2.84Å; D241-G243 PolarHBondContact O-N 3.18Å; D241-G244 WeakPolarHBondContact O-CA 3.49Å; D241-G244 PolarHBondContact O-N 2.94Å; D241-V260 HydrophobicContact CB-CG1 4.27Å; D241-V260 WeakPolarHBondContact O-CB 3.31Å; D241-V260 WeakPolarHBondContact O-CG1 3.36Å
242S78.1Confident68Low22 Ų2242.5 Ų42.515%0.15421%0.209CC..THydrogen-bonded Turntrans-40.3128.8174-76.50000112.9C51 G52 H72 G244C51-S242 CarbonylContact C-O 3.59Å; C51-S242 VanDerWaalsContact CA-O 3.31Å; C51-S242 WeakPolarHBondContact CA-O 3.28Å; C51-S242 WeakPolarHBondContact CB-O 3.33Å; C51-S242 VanDerWaalsContact SG-CB 3.56Å; G52-S242 PolarHBondContact N-O 3.38Å; H72-S242 WeakPolarHBondContact NE2-CB 3.44Å; H72-S242 PolarHBondContact NE2-OG 2.75Å; S242-G244 PolarHBondContact O-N 3.04Å
243G84.5Confident70.9Confident0 Ų044.4 Ų44.40%021%0.212CC..THydrogen-bonded Turntrans78.8-10.2-178.300000115.8G52 G53 T69 D241 V260G52-G243 CarbonylContact O-C 3.57Å; G52-G243 WeakPolarHBondContact O-CA 3.47Å; G53-G243 WeakPolarHBondContact CA-O 3.48Å; T69-G243 WeakPolarHBondContact OG1-CA 3.4Å; D241-G243 PolarHBondContact O-N 3.18Å; G243-V260 PolarHBondContact N-O 3.12Å
244G89Confident73.5Confident0 Ų040.4 Ų40.40%020%0.195CC..  trans-60.1159.5175.200000113.5D241 S242 I259 V260D241-G244 WeakPolarHBondContact O-CA 3.49Å; D241-G244 PolarHBondContact O-N 2.94Å; S242-G244 PolarHBondContact O-N 3.04Å; G244-I259 CarbonylContact O-C 3.51Å; G244-I259 WeakPolarHBondContact O-CA 3.49Å; G244-V260 WeakPolarHBondContact O-CG2 3.28Å; G244-V260 PolarHBondContact O-N 3.16Å
245A93.4Very high76.2Confident1 Ų139.5 Ų39.51%0.00819%0.188CC..EExtended strand (participates in β ladder)trans-86.1133.6-177.900000112.4V247 Q256A245-V247 HydrophobicContact CB-CG1 3.84Å; A245-Q256 HydrophobicContact CB-CG 4Å
246L92.6Very high78.8Confident0 Ų038.1 Ų38.10%018%0.18CC..EExtended strand (participates in β ladder)trans-93109.8158.5-173.4158.4000108.1C157 Y158 V159 I198 V200 F222 A224 Q256 Y257 G258 Y276C157-L246 HydrophobicContact CB-CD2 3.89Å; Y158-L246 WeakPolarHBondContact O-CA 3.4Å; V159-L246 HydrophobicContact CG2-CB 3.88Å; V159-L246 HydrophobicContact CG2-CD1 4.04Å; V159-L246 HydrophobicContact CG2-CG 3.9Å; I198-L246 HydrophobicContact CD1-CD1 4.49Å; I198-L246 HydrophobicContact CG2-CD1 3.71Å; I198-L246 HydrophobicContact CG2-CG 3.98Å; V200-L246 HydrophobicContact CG2-CD1 4.46Å; V200-L246 HydrophobicContact CG2-CD2 4.17Å; F222-L246 HydrophobicContact CE2-CD1 3.88Å; F222-L246 HydrophobicContact CE2-CD2 4.48Å; F222-L246 HydrophobicContact CZ-CD1 3.99Å; F222-L246 HydrophobicContact CZ-CD2 4.24Å; A224-L246 HydrophobicContact CB-CD1 3.89Å; L246-Q256 WeakPolarHBondContact O-CA 2.96Å; L246-Y257 PolarHBondContact O-N 3.41Å; L246-G258 PolarHBondContact N-O 2.94Å; L246-G258 PolarHBondContact O-N 2.86Å; L246-Y276 HydrophobicContact CB-CD1 3.99Å; L246-Y276 HydrophobicContact CB-CE1 4.19Å; L246-Y276 HydrophobicContact CD1-CD1 3.65Å; L246-Y276 HydrophobicContact CD1-CD2 4.23Å; L246-Y276 HydrophobicContact CD1-CE1 3.66Å; L246-Y276 HydrophobicContact CD1-CE2 4.27Å; L246-Y276 HydrophobicContact CD1-CG 3.96Å; L246-Y276 HydrophobicContact CG-CD1 4.49Å
247V94.7Very high81.3Confident2 Ų234.9 Ų34.91%0.01217%0.168CC..EExtended strand (participates in β ladder)trans-109.7135-177-57.70000111W33 V142 C157 Y158 A245 F254 I255 Q256W33-V247 HydrophobicContact CZ2-CG2 4.43Å; V142-V247 HydrophobicContact CG2-CG1 3.76Å; C157-V247 CarbonylContact C-O 3.5Å; C157-V247 WeakPolarHBondContact CA-O 3.12Å; Y158-V247 PolarHBondContact N-O 3.18Å; Y158-V247 PolarHBondContact O-N 3.04Å; A245-V247 HydrophobicContact CB-CG1 3.84Å; V247-F254 HydrophobicContact CB-CB 4.4Å; V247-F254 HydrophobicContact CB-CD1 4.36Å; V247-F254 HydrophobicContact CG2-CD1 3.93Å; V247-I255 CarbonylContact C-O 3.54Å; V247-I255 WeakPolarHBondContact CA-O 3.47Å; V247-Q256 HydrophobicContact CG1-CB 4.35Å
248C94.2Very high83.7Confident0 Ų033.8 Ų33.80%016%0.159CC..EExtended strand (participates in β ladder)trans-115.6139.3176.3-56.90000110.1P152 K155 K156 C157 E250 I255 Y257P152-C248 HydrophobicContact CB-CB 4.42Å; P152-C248 VanDerWaalsContact CG-SG 3.51Å; K155-C248 HydrophobicContact CB-CB 4.4Å; K156-C248 WeakPolarHBondContact O-CA 3.36Å; C157-C248 HydrophobicContact CB-CB 4.06Å; C157-C248 WeakPolarHBondContact CB-SG 3.45Å; C157-C248 WeakPolarHBondContact SG-CB 3.19Å; C157-C248 CovalentContact SG-SG 2.04Å; C157-C248 PolarHBondContact SG-SG 2.9Å; C248-E250 PolarHBondContact O-N 2.87Å; C248-I255 PolarHBondContact N-O 2.8Å; C248-I255 PolarHBondContact O-N 3.5Å; C248-Y257 HydrophobicContact CB-CD2 3.75Å; C248-Y257 HydrophobicContact CB-CE2 4.05Å
249H90.6Very high85.8Confident82 Ų8232.4 Ų32.438%0.3815%0.152SC..EExtended strand (participates in β ladder)trans-86.9109.2179.3-176.6-99.9000111.1K156 R253 F254K156-H249 PolarHBondContact O-N 3.28Å; H249-R253 CarbonylContact C-O 3.41Å; H249-R253 WeakPolarHBondContact CA-O 3.34Å; H249-F254 HydrophobicContact CB-CD1 4.17Å; H249-F254 HydrophobicContact CB-CE1 3.76Å; H249-F254 HydrophobicContact CB-CZ 4.18Å; H249-F254 AromaticContact CD2-CE2 3.77Å; H249-F254 AromaticContact CD2-CZ 3.7Å
250E89.1Confident87.9Confident12 Ų1226.4 Ų26.46%0.05612%0.124CC..EExtended strand (participates in β ladder)trans-135.7139180-63.1-151.8-116.200111.5K155 C248 G252 R253 I255 Y257K155-E250 HydrophobicContact CD-CG 4.15Å; K155-E250 WeakPolarHBondContact CE-OE2 3.1Å; K155-E250 HydrophobicContact CG-CG 4.44Å; K155-E250 IonicContact NZ-OE2 2.74Å; K155-E250 PolarHBondContact NZ-OE2 2.87Å; C248-E250 PolarHBondContact O-N 2.87Å; E250-G252 PolarHBondContact O-N 3.3Å; E250-R253 PolarHBondContact N-O 3.02Å; E250-R253 PolarHBondContact O-N 3.48Å; E250-I255 HydrophobicContact CB-CD1 4.02Å; E250-Y257 VanDerWaalsContact OE1-CE2 3.25Å; E250-Y257 WeakPolarHBondContact OE1-CE2 3.17Å; E250-Y257 VanDerWaalsContact OE1-CZ 3.26Å; E250-Y257 PolarHBondContact OE1-OH 3.3Å
251W85.4Confident89.3Confident220 Ų22026.4 Ų26.483%0.83312%0.124SC*.THydrogen-bonded Turntrans49.933.8179.6-48.1-59.9000114.6I255W251-I255 HydrophobicContact CE3-CD1 3.97Å; W251-I255 HydrophobicContact CZ3-CD1 3.9Å
252G85.7Confident89.1Confident40 Ų4026.5 Ų26.541%0.41212%0.123SC..THydrogen-bonded Turntrans78.812.4-178.800000114.9L8 E250L8-G252 WeakPolarHBondContact CD2-O 3.4Å; E250-G252 PolarHBondContact O-N 3.3Å
253R91.6Very high87.7Confident103 Ų10326.1 Ų26.139%0.38912%0.122SC..EExtended strand (participates in β ladder)trans-132.7154.8179.6-55.3-169.4179.5178.70.7111.7G7 L8 H249 E250G7-R253 CarbonylContact O-C 3.57Å; G7-R253 WeakPolarHBondContact O-CA 3.35Å; L8-R253 HydrophobicContact CD1-CG 4.03Å; L8-R253 HydrophobicContact CG-CG 4.06Å; H249-R253 CarbonylContact C-O 3.41Å; H249-R253 WeakPolarHBondContact CA-O 3.34Å; E250-R253 PolarHBondContact N-O 3.02Å; E250-R253 PolarHBondContact O-N 3.48Å
254F94.4Very high85.4Confident17 Ų1727.9 Ų27.98%0.07513%0.134CC..EExtended strand (participates in β ladder)trans-86.8117.9168.8-69.2-83.7000110.5G7 P9 L13 W33 V142 C143 Y158 V247 H249G7-F254 VanDerWaalsContact CA-O 3.3Å; G7-F254 WeakPolarHBondContact CA-O 3.5Å; G7-F254 WeakPolarHBondContact O-CD2 3.44Å; G7-F254 PolarHBondContact O-N 3.06Å; P9-F254 HydrophobicContact CG-CD2 4.36Å; P9-F254 HydrophobicContact CG-CE2 4.21Å; L13-F254 HydrophobicContact CD1-CE1 3.63Å; L13-F254 HydrophobicContact CD1-CE2 4.34Å; L13-F254 HydrophobicContact CD1-CZ 3.36Å; L13-F254 HydrophobicContact CG-CZ 3.96Å; W33-F254 HydrophobicContact CH2-CB 3.6Å; W33-F254 AromaticContact CH2-CD2 3.54Å; W33-F254 HydrophobicContact CH2-CD2 3.54Å; W33-F254 HydrophobicContact CH2-CE2 4.4Å; W33-F254 AromaticContact CH2-CG 3.62Å; W33-F254 HydrophobicContact CH2-CG 3.62Å; W33-F254 HydrophobicContact CZ2-CB 3.83Å; W33-F254 HydrophobicContact CZ2-CD1 4.46Å; W33-F254 HydrophobicContact CZ2-CD2 4.23Å; W33-F254 AromaticContact CZ2-CG 3.91Å; W33-F254 HydrophobicContact CZ2-CG 3.91Å; W33-F254 HydrophobicContact CZ3-CB 4.25Å; W33-F254 HydrophobicContact CZ3-CD2 4.42Å; V142-F254 HydrophobicContact CG2-CB 4.5Å; V142-F254 WeakPolarHBondContact CG2-O 3.33Å; C143-F254 PolarHBondContact N-O 3.46Å; Y158-F254 HydrophobicContact CD2-CE1 4.11Å; Y158-F254 HydrophobicContact CE2-CE1 4.1Å; V247-F254 HydrophobicContact CB-CB 4.4Å; V247-F254 HydrophobicContact CB-CD1 4.36Å; V247-F254 HydrophobicContact CG2-CD1 3.93Å; H249-F254 HydrophobicContact CB-CD1 4.17Å; H249-F254 HydrophobicContact CB-CE1 3.76Å; H249-F254 HydrophobicContact CB-CZ 4.18Å; H249-F254 AromaticContact CD2-CE2 3.77Å; H249-F254 AromaticContact CD2-CZ 3.7Å
255I96.4Very high82.6Confident15 Ų1532.6 Ų32.68%0.07717%0.173CC..EExtended strand (participates in β ladder)trans-109.9127.6177.1-52.6-178.3000107.7C143 P145 V247 C248 E250 W251 Y257C143-I255 HydrophobicContact CB-CG1 4.21Å; C143-I255 WeakPolarHBondContact O-CA 3.31Å; P145-I255 HydrophobicContact CB-CG2 3.79Å; V247-I255 CarbonylContact C-O 3.54Å; V247-I255 WeakPolarHBondContact CA-O 3.47Å; C248-I255 PolarHBondContact N-O 2.8Å; C248-I255 PolarHBondContact O-N 3.5Å; E250-I255 HydrophobicContact CB-CD1 4.02Å; W251-I255 HydrophobicContact CE3-CD1 3.97Å; W251-I255 HydrophobicContact CZ3-CD1 3.9Å; I255-Y257 HydrophobicContact CB-CD2 4.28Å; I255-Y257 HydrophobicContact CB-CE2 4Å; I255-Y257 HydrophobicContact CG2-CD2 4.16Å; I255-Y257 HydrophobicContact CG2-CE2 3.93Å; I255-Y257 PolarHBondContact O-N 2.81Å
256Q96.6Very high79.5Confident0 Ų034.4 Ų34.40%019%0.192CC..EExtended strand (participates in β ladder)trans-76.4122.8173.6-172.4173.9-5.200109.5S54 V142 C143 P145 A245 L246 V247 G258 L279S54-Q256 PolarHBondContact OG-OE1 3.42Å; V142-Q256 HydrophobicContact CG1-CB 3.89Å; V142-Q256 HydrophobicContact CG2-CB 3.93Å; C143-Q256 PolarHBondContact O-N 3.16Å; P145-Q256 WeakPolarHBondContact CD-O 3.48Å; P145-Q256 WeakPolarHBondContact CG-O 3.47Å; A245-Q256 HydrophobicContact CB-CG 4Å; L246-Q256 WeakPolarHBondContact O-CA 2.96Å; V247-Q256 HydrophobicContact CG1-CB 4.35Å; Q256-G258 VanDerWaalsContact CG-O 3.28Å; Q256-G258 WeakPolarHBondContact CG-O 3.43Å; Q256-G258 PolarHBondContact NE2-O 3.06Å; Q256-L279 HydrophobicContact CB-CD2 3.9Å; Q256-L279 HydrophobicContact CG-CD2 3.69Å
257Y96.4Very high76.4Confident11 Ų1138.8 Ų38.84%0.04321%0.214CC..EExtended strand (participates in β ladder)trans-108.8-23.8174.9-84.5-87.3000112.7P145 A149 R150 P152 F222 L246 C248 E250 I255 F278 L279 P280P145-Y257 HydrophobicContact CB-CD1 4.39Å; P145-Y257 HydrophobicContact CB-CE1 4.29Å; A149-Y257 HydrophobicContact CB-CE1 3.83Å; R150-Y257 WeakPolarHBondContact O-CE1 3.21Å; P152-Y257 HydrophobicContact CB-CD1 4.41Å; P152-Y257 HydrophobicContact CB-CD2 4.15Å; P152-Y257 HydrophobicContact CB-CE1 4.27Å; P152-Y257 HydrophobicContact CB-CE2 3.99Å; P152-Y257 HydrophobicContact CB-CG 4.32Å; P152-Y257 HydrophobicContact CG-CD1 3.83Å; P152-Y257 HydrophobicContact CG-CD2 3.83Å; P152-Y257 HydrophobicContact CG-CE1 4.18Å; P152-Y257 HydrophobicContact CG-CE2 4.16Å; P152-Y257 HydrophobicContact CG-CG 3.61Å; F222-Y257 WeakPolarHBondContact CE1-O 3.5Å; L246-Y257 PolarHBondContact O-N 3.41Å; C248-Y257 HydrophobicContact CB-CD2 3.75Å; C248-Y257 HydrophobicContact CB-CE2 4.05Å; E250-Y257 VanDerWaalsContact OE1-CE2 3.25Å; E250-Y257 WeakPolarHBondContact OE1-CE2 3.17Å; E250-Y257 VanDerWaalsContact OE1-CZ 3.26Å; E250-Y257 PolarHBondContact OE1-OH 3.3Å; I255-Y257 HydrophobicContact CB-CD2 4.28Å; I255-Y257 HydrophobicContact CB-CE2 4Å; I255-Y257 HydrophobicContact CG2-CD2 4.16Å; I255-Y257 HydrophobicContact CG2-CE2 3.93Å; I255-Y257 PolarHBondContact O-N 2.81Å; Y257-F278 HydrophobicContact CD1-CE2 4.37Å; Y257-L279 WeakPolarHBondContact O-CB 3.4Å; Y257-L279 PolarHBondContact O-N 3.23Å; Y257-P280 HydrophobicContact CD1-CG 4.17Å
258G93.9Very high73.3Confident0 Ų041.2 Ų41.20%024%0.24CC..EExtended strand (participates in β ladder)trans-132.9159.3-178.800000114.5L246 Q256 T277L246-G258 PolarHBondContact N-O 2.94Å; L246-G258 PolarHBondContact O-N 2.86Å; Q256-G258 VanDerWaalsContact CG-O 3.28Å; Q256-G258 WeakPolarHBondContact CG-O 3.43Å; Q256-G258 PolarHBondContact NE2-O 3.06Å; G258-T277 VanDerWaalsContact CA-O 3.31Å; G258-T277 WeakPolarHBondContact CA-O 3.07Å
259I93Very high70.4Confident0 Ų047.7 Ų47.70%027%0.265CS..EExtended strand (participates in β ladder)trans-115132.9163.1-54.2171.5000106.1L68 A70 I124 G244 S261 Y276 T277 L279L68-I259 HydrophobicContact CD1-CD1 3.8Å; L68-I259 HydrophobicContact CD2-CD1 4.1Å; L68-I259 HydrophobicContact CD2-CG1 4.29Å; L68-I259 HydrophobicContact CG-CD1 3.83Å; L68-I259 HydrophobicContact CG-CG1 4.32Å; A70-I259 HydrophobicContact CB-CG2 4.04Å; I124-I259 HydrophobicContact CB-CD1 4.2Å; I124-I259 HydrophobicContact CD1-CD1 4.01Å; I124-I259 HydrophobicContact CG1-CD1 3.67Å; G244-I259 CarbonylContact O-C 3.51Å; G244-I259 WeakPolarHBondContact O-CA 3.49Å; I259-S261 PolarHBondContact O-N 2.94Å; I259-S261 VanDerWaalsContact O-N 3.13Å; I259-Y276 VanDerWaalsContact O-CA 3.27Å; I259-Y276 WeakPolarHBondContact O-CA 3.46Å; I259-T277 PolarHBondContact N-O 3.16Å; I259-T277 PolarHBondContact O-N 3.3Å; I259-L279 HydrophobicContact CD1-CD1 4.38Å
260V88.4Confident67.7Low1 Ų153.1 Ų53.11%0.00628%0.284CS..EExtended strand (participates in β ladder)trans-62.4113.1174.4178.30000108.1V159 A237 D241 G243 G244 Y276V159-V260 HydrophobicContact CG1-CG2 3.64Å; A237-V260 HydrophobicContact CB-CG1 3.93Å; D241-V260 HydrophobicContact CB-CG1 4.27Å; D241-V260 WeakPolarHBondContact O-CB 3.31Å; D241-V260 WeakPolarHBondContact O-CG1 3.36Å; G243-V260 PolarHBondContact N-O 3.12Å; G244-V260 WeakPolarHBondContact O-CG2 3.28Å; G244-V260 PolarHBondContact O-N 3.16Å; V260-Y276 HydrophobicContact CB-CE1 4.41Å; V260-Y276 HydrophobicContact CG2-CD1 4.39Å; V260-Y276 HydrophobicContact CG2-CE1 3.83Å
261S80.6Confident65.5Low1 Ų158.9 Ų58.91%0.00731%0.311CS..  trans-104.3-123.3179.4178.90000108.3D123 I259 K275D123-S261 WeakPolarHBondContact OD2-CA 3.49Å; D123-S261 VanDerWaalsContact OD2-CB 3.24Å; D123-S261 WeakPolarHBondContact OD2-CB 3.48Å; D123-S261 PolarHBondContact OD2-OG 2.92Å; I259-S261 PolarHBondContact O-N 2.94Å; I259-S261 VanDerWaalsContact O-N 3.13Å; S261-K275 WeakPolarHBondContact CB-O 3.23Å; S261-K275 PolarHBondContact N-O 3.08Å
262F62Low63.8Low29 Ų2949.3 Ų49.313%0.12728%0.276CS..  trans-91.5145.1-177.9-68.8-85.5000114H72 Y115 D118 F119 K275H72-F262 HydrophobicContact CB-CE2 4.17Å; H72-F262 HydrophobicContact CB-CZ 3.7Å; H72-F262 AromaticContact CG-CZ 3.82Å; H72-F262 AromaticContact ND1-CE2 3.89Å; H72-F262 AromaticContact ND1-CZ 3.97Å; Y115-F262 HydrophobicContact CE2-CE2 4.29Å; Y115-F262 VanDerWaalsContact OH-CZ 3.26Å; Y115-F262 WeakPolarHBondContact OH-CZ 3.46Å; D118-F262 HydrophobicContact CB-CE1 4.32Å; D118-F262 HydrophobicContact CB-CZ 4.17Å; F119-F262 HydrophobicContact CD1-CB 3.56Å; F119-F262 AromaticContact CD1-CD1 3.8Å; F119-F262 HydrophobicContact CD1-CD1 3.8Å; F119-F262 AromaticContact CD1-CD2 3.99Å; F119-F262 HydrophobicContact CD1-CD2 3.99Å; F119-F262 AromaticContact CD1-CG 3.48Å; F119-F262 HydrophobicContact CD1-CG 3.48Å; F119-F262 VanDerWaalsContact CD1-CG 3.48Å; F119-F262 HydrophobicContact CE1-CB 3.72Å; F119-F262 AromaticContact CE1-CD1 3.61Å; F119-F262 HydrophobicContact CE1-CD1 3.61Å; F119-F262 HydrophobicContact CE1-CE1 4.43Å; F119-F262 AromaticContact CE1-CG 3.73Å; F119-F262 HydrophobicContact CE1-CG 3.73Å; F119-F262 HydrophobicContact CG-CG 4.37Å; F119-F262 HydrophobicContact CZ-CD1 4.29Å; F119-F262 VanDerWaalsContact N-CE2 3.31Å; F262-K275 VanDerWaalsContact O-CB 3.25Å; F262-K275 WeakPolarHBondContact O-CB 3.22Å; F262-K275 WeakPolarHBondContact O-CG 3.45Å; F262-K275 PolarHBondContact O-N 3.23Å
263G49.5Very low62.4Low14 Ų1447.6 Ų47.614%0.14426%0.258CS..  trans-111.8165.3162.300000110.7A265G263-A265 PolarHBondContact O-N 3.25Å
264P35.7Very low61.3Low37 Ų3742.7 Ų42.724%0.2424%0.24CC..  trans-62.3118178.426.4-36.4000112.3G266 T272P264-G266 PolarHBondContact O-N 3.36Å; P264-T272 WeakPolarHBondContact CB-OG1 3.39Å; P264-T272 VanDerWaalsContact CG-OG1 3.28Å; P264-T272 WeakPolarHBondContact CG-OG1 3.26Å
265A30.2Very low60.6Low99 Ų9943 Ų4382%0.81824%0.242SC*.  trans-89.870.7175.100000110.8G263G263-A265 PolarHBondContact O-N 3.25Å
266G28.6Very low60.3Low39 Ų3942.6 Ų42.640%0.40224%0.239SC..SBendtrans-172.1146.2176.800000114.1P264P264-G266 PolarHBondContact O-N 3.36Å
267I27.1Very low60.1Low92 Ų9242.6 Ų42.647%0.47224%0.239SC..SBendtrans-88.9100.4167.2-60.9172.4000106.4L170 L171L170-I267 HydrophobicContact CD2-CD1 4.42Å; L170-I267 HydrophobicContact CG-CD1 4.46Å; L171-I267 HydrophobicContact CD2-CD1 4.43Å; L171-I267 HydrophobicContact CD2-CG2 3.67Å
268G29.6Very low60.1Low54 Ų5442.9 Ų42.956%0.55724%0.24SC*.SBendtrans164.3-32.5-179.400000114.1Y270G268-Y270 PolarHBondContact O-N 2.93Å
269Y32.7Very low60.2Low136 Ų13642.9 Ų42.953%0.53324%0.24SC..  trans-96.387.2-176.1-67.6-88.7000112.2D211 Q271 T272D211-Y269 HydrophobicContact CB-CE1 4.31Å; D211-Y269 WeakPolarHBondContact OD2-CE1 3.31Å; D211-Y269 PolarHBondContact OD2-OH 3.38Å; Y269-Q271 PolarHBondContact O-N 3.36Å; Y269-T272 WeakPolarHBondContact CB-OG1 3.46Å; Y269-T272 HydrophobicContact CD1-CG2 3.83Å; Y269-T272 HydrophobicContact CG-CG2 4.16Å
270Y35.4Very low60.3Low195 Ų19543 Ų4377%0.76524%0.241SC*.SBendtrans-734.9174.2-76.4-81.1000114.4G268G268-Y270 PolarHBondContact O-N 2.93Å
271Q41.8Very low60.7Low134 Ų13447.4 Ų47.463%0.62626%0.26SS*.SBendtrans-129.6-16.5-167.7-62.1-177.40.400115L209 Y269 A273L209-Q271 WeakPolarHBondContact CB-O 3.29Å; L209-Q271 WeakPolarHBondContact CD2-O 3.43Å; Y269-Q271 PolarHBondContact O-N 3.36Å; Q271-A273 PolarHBondContact O-N 2.66Å
272T49.3Very low61.4Low18 Ų1848.1 Ų48.111%0.1126%0.263CS..PPolyproline II helixtrans-78.1116.8-172.746.10000113.5L209 D211 V234 P264 Y269L209-T272 VanDerWaalsContact O-CA 3.24Å; L209-T272 WeakPolarHBondContact O-CA 3.48Å; D211-T272 HydrophobicContact CB-CG2 4.29Å; V234-T272 VanDerWaalsContact CG1-O 3.28Å; V234-T272 WeakPolarHBondContact CG1-O 3.34Å; V234-T272 WeakPolarHBondContact CG2-O 3.37Å; P264-T272 WeakPolarHBondContact CB-OG1 3.39Å; P264-T272 VanDerWaalsContact CG-OG1 3.28Å; P264-T272 WeakPolarHBondContact CG-OG1 3.26Å; Y269-T272 WeakPolarHBondContact CB-OG1 3.46Å; Y269-T272 HydrophobicContact CD1-CG2 3.83Å; Y269-T272 HydrophobicContact CG-CG2 4.16Å
273A56.3Low63Low4 Ų447.1 Ų47.13%0.03326%0.26CS..PPolyproline II helixtrans-65.9154-175.900000115.1I201 L209 C223 V234 Q271I201-A273 HydrophobicContact CD1-CB 4.27Å; L209-A273 HydrophobicContact CB-CB 4Å; L209-A273 HydrophobicContact CD1-CB 4.27Å; C223-A273 HydrophobicContact CB-CB 3.72Å; C223-A273 WeakPolarHBondContact SG-CB 3.25Å; V234-A273 VanDerWaalsContact CG1-C 3.48Å; V234-A273 VanDerWaalsContact CG1-CA 3.5Å; V234-A273 HydrophobicContact CG2-CB 4.33Å; Q271-A273 PolarHBondContact O-N 2.66Å
274G69.7Low65.2Low1 Ų147.7 Ų47.71%0.0127%0.266CS..EExtended strand (participates in β ladder)trans-74.3128.2-179.900000109.4C223 A224 Y276C223-G274 WeakPolarHBondContact CA-O 3.39Å; A224-G274 PolarHBondContact N-O 2.91Å; G274-Y276 WeakPolarHBondContact O-CD2 3.35Å; G274-Y276 VanDerWaalsContact O-CE2 3.3Å; G274-Y276 WeakPolarHBondContact O-CE2 3.21Å
275K80.5Confident68.1Low23 Ų2348.3 Ų48.310%0.126%0.263CS..EExtended strand (participates in β ladder)trans-89.8134.4-176-48.4-167.9176.5-176.70110.4S214 E215 F216 S261 F262S214-K275 PolarHBondContact OG-NZ 3.16Å; E215-K275 PolarHBondContact O-NZ 2.87Å; F216-K275 HydrophobicContact CD2-CD 3.9Å; F216-K275 HydrophobicContact CD2-CG 4.29Å; F216-K275 HydrophobicContact CE2-CB 4.26Å; F216-K275 HydrophobicContact CE2-CD 3.98Å; F216-K275 HydrophobicContact CE2-CG 3.89Å; S261-K275 WeakPolarHBondContact CB-O 3.23Å; S261-K275 PolarHBondContact N-O 3.08Å; F262-K275 VanDerWaalsContact O-CB 3.25Å; F262-K275 WeakPolarHBondContact O-CB 3.22Å; F262-K275 WeakPolarHBondContact O-CG 3.45Å; F262-K275 PolarHBondContact O-N 3.23Å
276Y89Confident71.3Confident6 Ų643.6 Ų43.62%0.02422%0.224CC..EExtended strand (participates in β ladder)trans-129.3136.2177.7-64-92.8000110.2V159 I198 Q221 F222 A224 L246 I259 V260 G274 F278V159-Y276 HydrophobicContact CG2-CE1 3.85Å; I198-Y276 HydrophobicContact CD1-CE2 4.05Å; I198-Y276 WeakPolarHBondContact CD1-OH 3.14Å; Q221-Y276 CarbonylContact C-O 3.54Å; Q221-Y276 VanDerWaalsContact CA-O 3.25Å; Q221-Y276 WeakPolarHBondContact CA-O 3.38Å; F222-Y276 WeakPolarHBondContact CD1-O 3.47Å; F222-Y276 VanDerWaalsContact CE1-CB 3.46Å; F222-Y276 HydrophobicContact CE2-CD2 4.32Å; F222-Y276 HydrophobicContact CE2-CG 4.16Å; F222-Y276 VanDerWaalsContact CZ-CB 3.49Å; F222-Y276 HydrophobicContact CZ-CG 4.08Å; F222-Y276 PolarHBondContact N-O 3.16Å; F222-Y276 PolarHBondContact O-N 2.88Å; A224-Y276 HydrophobicContact CB-CD2 3.89Å; A224-Y276 HydrophobicContact CB-CE2 3.6Å; L246-Y276 HydrophobicContact CB-CD1 3.99Å; L246-Y276 HydrophobicContact CB-CE1 4.19Å; L246-Y276 HydrophobicContact CD1-CD1 3.65Å; L246-Y276 HydrophobicContact CD1-CD2 4.23Å; L246-Y276 HydrophobicContact CD1-CE1 3.66Å; L246-Y276 HydrophobicContact CD1-CE2 4.27Å; L246-Y276 HydrophobicContact CD1-CG 3.96Å; L246-Y276 HydrophobicContact CG-CD1 4.49Å; I259-Y276 VanDerWaalsContact O-CA 3.27Å; I259-Y276 WeakPolarHBondContact O-CA 3.46Å; V260-Y276 HydrophobicContact CB-CE1 4.41Å; V260-Y276 HydrophobicContact CG2-CD1 4.39Å; V260-Y276 HydrophobicContact CG2-CE1 3.83Å; G274-Y276 WeakPolarHBondContact O-CD2 3.35Å; G274-Y276 VanDerWaalsContact O-CE2 3.3Å; G274-Y276 WeakPolarHBondContact O-CE2 3.21Å; Y276-F278 PolarHBondContact O-N 3.03Å
277T93.2Very high74.5Confident0 Ų044.5 Ų44.50%022%0.218CC..EExtended strand (participates in β ladder)trans-70.7123.1172.8-51.40000109.3D123 I124 G258 I259 L279 F282D123-T277 WeakPolarHBondContact O-CB 3.45Å; D123-T277 PolarHBondContact O-OG1 3.06Å; I124-T277 HydrophobicContact CB-CG2 4.44Å; G258-T277 VanDerWaalsContact CA-O 3.31Å; G258-T277 WeakPolarHBondContact CA-O 3.07Å; I259-T277 PolarHBondContact N-O 3.16Å; I259-T277 PolarHBondContact O-N 3.3Å; T277-L279 PolarHBondContact O-N 3.25Å; T277-L279 VanDerWaalsContact O-N 3.11Å; T277-F282 HydrophobicContact CG2-CD2 3.86Å; T277-F282 HydrophobicContact CG2-CE2 3.38Å; T277-F282 HydrophobicContact CG2-CZ 3.99Å
278F95.5Very high77.8Confident17 Ų1746.2 Ų46.28%0.07522%0.222CC..EExtended strand (participates in β ladder)trans-77.894.1-176.1-170.5-129.5000111.2A149 L151 K220 F222 Y257 Y276 P280 K281 F282A149-F278 WeakPolarHBondContact O-CZ 3.43Å; L151-F278 HydrophobicContact CD1-CD2 4.13Å; L151-F278 HydrophobicContact CD1-CE2 3.94Å; K220-F278 WeakPolarHBondContact O-CB 3.41Å; K220-F278 PolarHBondContact O-N 2.9Å; F222-F278 HydrophobicContact CD1-CB 3.82Å; F222-F278 AromaticContact CD1-CD2 3.69Å; F222-F278 HydrophobicContact CD1-CD2 3.69Å; F222-F278 HydrophobicContact CD1-CG 4.17Å; F222-F278 HydrophobicContact CE1-CB 4.39Å; F222-F278 AromaticContact CE1-CD2 3.98Å; F222-F278 HydrophobicContact CE1-CD2 3.98Å; F222-F278 HydrophobicContact CG-CD2 4.46Å; Y257-F278 HydrophobicContact CD1-CE2 4.37Å; Y276-F278 PolarHBondContact O-N 3.03Å; F278-P280 HydrophobicContact CD2-CG 4.24Å; F278-P280 HydrophobicContact CE1-CB 4.05Å; F278-P280 HydrophobicContact CE1-CG 4.03Å; F278-P280 HydrophobicContact CE2-CG 3.73Å; F278-P280 HydrophobicContact CZ-CB 4.09Å; F278-P280 HydrophobicContact CZ-CG 3.61Å; F278-K281 HydrophobicContact CD1-CG 4Å; F278-K281 PolarHBondContact O-N 2.82Å; F278-F282 WeakPolarHBondContact O-CD2 3.4Å
279L96.3Very high80.9Confident0 Ų044.9 Ų44.90%020%0.202CC..G310 helixtrans-55.5-37-169-171.354.8000115.7L68 I124 L144 P145 Q256 Y257 I259 T277 K281 F282 V283 I286L68-L279 HydrophobicContact CD1-CD1 4.41Å; L68-L279 HydrophobicContact CD2-CD1 3.65Å; L68-L279 HydrophobicContact CD2-CD2 3.55Å; L68-L279 HydrophobicContact CD2-CG 4.28Å; I124-L279 HydrophobicContact CD1-CD1 4.08Å; L144-L279 HydrophobicContact CD2-CD2 3.84Å; P145-L279 HydrophobicContact CG-CB 4.27Å; P145-L279 HydrophobicContact CG-CD2 4.44Å; P145-L279 HydrophobicContact CG-CG 4.17Å; Q256-L279 HydrophobicContact CB-CD2 3.9Å; Q256-L279 HydrophobicContact CG-CD2 3.69Å; Y257-L279 WeakPolarHBondContact O-CB 3.4Å; Y257-L279 PolarHBondContact O-N 3.23Å; I259-L279 HydrophobicContact CD1-CD1 4.38Å; T277-L279 PolarHBondContact O-N 3.25Å; T277-L279 VanDerWaalsContact O-N 3.11Å; L279-K281 VanDerWaalsContact C-N 3.25Å; L279-K281 PolarHBondContact O-N 3.48Å; L279-K281 VanDerWaalsContact O-N 3.12Å; L279-F282 PolarHBondContact O-N 3.31Å; L279-V283 PolarHBondContact O-N 3.15Å; L279-I286 HydrophobicContact CD1-CD1 3.73Å
280P96.1Very high83.9Confident2 Ų240.5 Ų40.51%0.01319%0.188CC..G310 helixtrans-50.2-38.1180-32.438.6000115.3P145 A149 Y257 F278 F282P145-P280 HydrophobicContact CB-CG 3.95Å; P145-P280 HydrophobicContact CG-CB 4.36Å; P145-P280 HydrophobicContact CG-CG 3.71Å; A149-P280 HydrophobicContact CB-CB 4.42Å; A149-P280 HydrophobicContact CB-CG 4.1Å; Y257-P280 HydrophobicContact CD1-CG 4.17Å; F278-P280 HydrophobicContact CD2-CG 4.24Å; F278-P280 HydrophobicContact CE1-CB 4.05Å; F278-P280 HydrophobicContact CE1-CG 4.03Å; F278-P280 HydrophobicContact CE2-CG 3.73Å; F278-P280 HydrophobicContact CZ-CB 4.09Å; F278-P280 HydrophobicContact CZ-CG 3.61Å; P280-F282 VanDerWaalsContact C-N 3.27Å; P280-F282 PolarHBondContact O-N 2.88Å
281K95.2Very high86.7Confident95 Ų9539.6 Ų39.641%0.41319%0.187SC..G310 helixtrans-68.8-25.8178.9-59.2-61.4177.2157.30113.4E219 F278 L279E219-K281 VanDerWaalsContact O-CE 3.28Å; E219-K281 WeakPolarHBondContact O-CE 3.49Å; E219-K281 WeakPolarHBondContact O-CG 3.37Å; E219-K281 IonicContact OE1-NZ 3.73Å; E219-K281 WeakPolarHBondContact OE2-CE 3.17Å; E219-K281 IonicContact OE2-NZ 2.59Å; E219-K281 PolarHBondContact OE2-NZ 3.2Å; F278-K281 HydrophobicContact CD1-CG 4Å; F278-K281 PolarHBondContact O-N 2.82Å; L279-K281 VanDerWaalsContact C-N 3.25Å; L279-K281 PolarHBondContact O-N 3.48Å; L279-K281 VanDerWaalsContact O-N 3.12Å
282F96.4Very high89.2Confident15 Ų1540.4 Ų40.47%0.06619%0.189CC..THydrogen-bonded Turntrans-95.9-10.4-175.2-62-84.2000113.7I124 K220 T277 F278 L279 P280 G284 W285 I286I124-F282 HydrophobicContact CD1-CB 3.46Å; I124-F282 VanDerWaalsContact CD1-CB 3.46Å; I124-F282 HydrophobicContact CD1-CD1 4.31Å; I124-F282 HydrophobicContact CD1-CD2 4.47Å; I124-F282 HydrophobicContact CD1-CG 3.85Å; I124-F282 HydrophobicContact CG2-CD1 3.7Å; I124-F282 HydrophobicContact CG2-CE1 3.89Å; I124-F282 HydrophobicContact CG2-CG 4.22Å; K220-F282 HydrophobicContact CB-CE2 4.1Å; K220-F282 HydrophobicContact CB-CZ 4.03Å; K220-F282 HydrophobicContact CD-CZ 3.98Å; K220-F282 HydrophobicContact CG-CE2 4.38Å; K220-F282 HydrophobicContact CG-CZ 4.06Å; T277-F282 HydrophobicContact CG2-CD2 3.86Å; T277-F282 HydrophobicContact CG2-CE2 3.38Å; T277-F282 HydrophobicContact CG2-CZ 3.99Å; F278-F282 WeakPolarHBondContact O-CD2 3.4Å; L279-F282 PolarHBondContact O-N 3.31Å; P280-F282 VanDerWaalsContact C-N 3.27Å; P280-F282 PolarHBondContact O-N 2.88Å; F282-G284 VanDerWaalsContact C-N 3.26Å; F282-G284 PolarHBondContact O-N 3.06Å; F282-W285 CarbonylContact O-C 3.3Å; F282-W285 WeakPolarHBondContact O-CA 3.32Å; F282-W285 WeakPolarHBondContact O-CB 3.49Å; F282-W285 PolarHBondContact O-N 2.78Å; F282-I286 WeakPolarHBondContact O-CG1 3.33Å; F282-I286 PolarHBondContact O-N 2.83Å
283V96.1Very high91.4Very high9 Ų940.3 Ų40.36%0.05519%0.187CC..Hα-helixtrans-53-42.2179.8173.60000112.3P145 R147 L279 W285 I286 E287P145-V283 HydrophobicContact CG-CG2 4.09Å; R147-V283 HydrophobicContact CG-CB 3.92Å; R147-V283 HydrophobicContact CG-CG1 3.85Å; L279-V283 PolarHBondContact O-N 3.15Å; V283-W285 VanDerWaalsContact C-N 3.32Å; V283-W285 PolarHBondContact O-N 2.6Å; V283-I286 WeakPolarHBondContact O-CB 3.4Å; V283-I286 PolarHBondContact O-N 3.5Å; V283-E287 PolarHBondContact O-N 2.79Å
284G95.6Very high93.2Very high26 Ų2644.5 Ų44.527%0.26821%0.209SC..Hα-helixtrans-69-24.8175.200000114.8F282 K288F282-G284 VanDerWaalsContact C-N 3.26Å; F282-G284 PolarHBondContact O-N 3.06Å; G284-K288 WeakPolarHBondContact O-CB 3.47Å; G284-K288 PolarHBondContact O-N 3.31Å
285W96.2Very high94.4Very high49 Ų4949 Ų4919%0.18624%0.238CC..Hα-helixtrans-75.3-39.6169.616992.1000110.8A111 M112 I124 L126 F282 V283 E287 K288 M289A111-W285 HydrophobicContact CB-CZ2 4.35Å; M112-W285 VanDerWaalsContact O-CZ2 3.32Å; M112-W285 WeakPolarHBondContact O-CZ2 3.45Å; I124-W285 HydrophobicContact CB-CZ3 4.5Å; I124-W285 HydrophobicContact CD1-CE3 3.91Å; I124-W285 HydrophobicContact CD1-CZ3 3.67Å; I124-W285 HydrophobicContact CG1-CE3 4.42Å; I124-W285 HydrophobicContact CG1-CH2 4.42Å; I124-W285 HydrophobicContact CG1-CZ3 3.75Å; I124-W285 HydrophobicContact CG2-CE3 4.27Å; I124-W285 HydrophobicContact CG2-CH2 4.3Å; I124-W285 HydrophobicContact CG2-CZ3 4.01Å; L126-W285 HydrophobicContact CD1-CE3 4.42Å; L126-W285 HydrophobicContact CD1-CH2 3.87Å; L126-W285 HydrophobicContact CD1-CZ3 3.69Å; L126-W285 HydrophobicContact CG-CH2 3.86Å; L126-W285 HydrophobicContact CG-CZ3 3.75Å; F282-W285 CarbonylContact O-C 3.3Å; F282-W285 WeakPolarHBondContact O-CA 3.32Å; F282-W285 WeakPolarHBondContact O-CB 3.49Å; F282-W285 PolarHBondContact O-N 2.78Å; V283-W285 VanDerWaalsContact C-N 3.32Å; V283-W285 PolarHBondContact O-N 2.6Å; W285-E287 PolarHBondContact O-N 3.06Å; W285-K288 WeakPolarHBondContact O-CB 3.42Å; W285-K288 PolarHBondContact O-N 3Å; W285-K288 VanDerWaalsContact O-N 3.08Å; W285-M289 HydrophobicContact CD2-CG 3.91Å; W285-M289 HydrophobicContact CG-CG 4.35Å; W285-M289 HydrophobicContact CH2-CG 4.14Å; W285-M289 HydrophobicContact CZ2-CG 3.47Å; W285-M289 VanDerWaalsContact CZ2-CG 3.47Å; W285-M289 HydrophobicContact CZ2-SD 4.32Å; W285-M289 WeakPolarHBondContact O-CG 3.34Å; W285-M289 PolarHBondContact O-N 3.28Å
286I96.8Very high95Very high0 Ų049.1 Ų49.10%024%0.241CC..Hα-helixtrans-58.7-50.6176.4-62.5172.9000110.6I56 L58 M66 L68 I124 L126 L144 L279 F282 V283 K288 M289 D290I56-I286 HydrophobicContact CD1-CG2 3.97Å; L58-I286 HydrophobicContact CD1-CG2 4.22Å; L58-I286 HydrophobicContact CD2-CG2 4.04Å; L58-I286 HydrophobicContact CG-CG2 4.46Å; M66-I286 HydrophobicContact CE-CG2 4Å; L68-I286 HydrophobicContact CD1-CD1 4.01Å; L68-I286 HydrophobicContact CD2-CD1 4.49Å; I124-I286 HydrophobicContact CD1-CD1 4.21Å; I124-I286 HydrophobicContact CD1-CG1 4.27Å; L126-I286 HydrophobicContact CD1-CB 4.24Å; L126-I286 HydrophobicContact CD1-CG1 4.25Å; L126-I286 HydrophobicContact CD1-CG2 3.95Å; L126-I286 HydrophobicContact CD2-CG1 4.28Å; L126-I286 HydrophobicContact CD2-CG2 4.06Å; L144-I286 HydrophobicContact CD2-CD1 4.43Å; L279-I286 HydrophobicContact CD1-CD1 3.73Å; F282-I286 WeakPolarHBondContact O-CG1 3.33Å; F282-I286 PolarHBondContact O-N 2.83Å; V283-I286 WeakPolarHBondContact O-CB 3.4Å; V283-I286 PolarHBondContact O-N 3.5Å; I286-K288 PolarHBondContact O-N 2.96Å; I286-M289 PolarHBondContact O-N 3.2Å; I286-M289 VanDerWaalsContact O-N 3.16Å; I286-D290 PolarHBondContact O-N 3.14Å
287E95.9Very high95.1Very high59 Ų5955.8 Ų55.828%0.27627%0.271SS..Hα-helixtrans-60.8-28176-68.5171.7-120.800113.9L58 R147 V283 W285 K291L58-E287 HydrophobicContact CD1-CG 4.32Å; L58-E287 HydrophobicContact CD2-CG 4.01Å; R147-E287 IonicContact CZ-OE1 3.82Å; R147-E287 VanDerWaalsContact CZ-OE1 3.28Å; R147-E287 IonicContact CZ-OE2 3.28Å; R147-E287 IonicContact NE-OE1 2.65Å; R147-E287 PolarHBondContact NE-OE1 2.85Å; R147-E287 IonicContact NH2-OE1 3.86Å; R147-E287 PolarHBondContact NH2-OE1 2.84Å; R147-E287 IonicContact NH2-OE2 3.24Å; R147-E287 PolarHBondContact NH2-OE2 3.38Å; V283-E287 PolarHBondContact O-N 2.79Å; W285-E287 PolarHBondContact O-N 3.06Å; E287-K291 WeakPolarHBondContact O-CG 3.38Å
288K96.5Very high95.1Very high127 Ų12759.7 Ų59.755%0.55229%0.292SS*.Hα-helixtrans-79-35.8177-174.9-173.7177.6-177.80111.6G284 W285 I286G284-K288 WeakPolarHBondContact O-CB 3.47Å; G284-K288 PolarHBondContact O-N 3.31Å; W285-K288 WeakPolarHBondContact O-CB 3.42Å; W285-K288 PolarHBondContact O-N 3Å; W285-K288 VanDerWaalsContact O-N 3.08Å; I286-K288 PolarHBondContact O-N 2.96Å
289M95.6Very high94.9Very high27 Ų2763.4 Ų63.413%0.13331%0.312CS..Hα-helixtrans-77.1-39.5179.1-69.1-52.195.800112.1A111 L126 W285 I286 K291 K292 M293A111-M289 HydrophobicContact CB-CB 4.04Å; A111-M289 HydrophobicContact CB-CG 3.95Å; A111-M289 HydrophobicContact CB-SD 4.17Å; L126-M289 HydrophobicContact CD1-CB 3.79Å; L126-M289 HydrophobicContact CD1-CG 4.45Å; W285-M289 HydrophobicContact CD2-CG 3.91Å; W285-M289 HydrophobicContact CG-CG 4.35Å; W285-M289 HydrophobicContact CH2-CG 4.14Å; W285-M289 HydrophobicContact CZ2-CG 3.47Å; W285-M289 VanDerWaalsContact CZ2-CG 3.47Å; W285-M289 HydrophobicContact CZ2-SD 4.32Å; W285-M289 WeakPolarHBondContact O-CG 3.34Å; W285-M289 PolarHBondContact O-N 3.28Å; I286-M289 PolarHBondContact O-N 3.2Å; I286-M289 VanDerWaalsContact O-N 3.16Å; M289-K291 PolarHBondContact O-N 3.46Å; M289-K291 VanDerWaalsContact O-N 3.16Å; M289-K292 HydrophobicContact CE-CD 4.07Å; M289-K292 WeakPolarHBondContact O-CA 3.34Å; M289-K292 PolarHBondContact O-N 3.16Å; M289-M293 HydrophobicContact CB-SD 4.42Å; M289-M293 WeakPolarHBondContact O-CG 3.22Å; M289-M293 PolarHBondContact O-N 2.8Å
290D94.1Very high94.5Very high44 Ų4465 Ų6524%0.23532%0.321CS..Hα-helixtrans-53.7-37.9176.517859.2000112.5L58 M66 R128 I286 K292L58-D290 HydrophobicContact CD1-CB 3.45Å; L58-D290 VanDerWaalsContact CD1-CB 3.45Å; M66-D290 HydrophobicContact CE-CB 4.21Å; M66-D290 HydrophobicContact SD-CB 4.33Å; R128-D290 IonicContact CZ-OD1 3.57Å; R128-D290 VanDerWaalsContact CZ-OD1 3.24Å; R128-D290 IonicContact NH1-OD1 2.82Å; R128-D290 PolarHBondContact NH1-OD1 3.01Å; R128-D290 PolarHBondContact NH2-O 2.79Å; R128-D290 IonicContact NH2-OD1 2.75Å; R128-D290 PolarHBondContact NH2-OD1 3.4Å; I286-D290 PolarHBondContact O-N 3.14Å; D290-K292 VanDerWaalsContact C-N 3.29Å; D290-K292 PolarHBondContact O-N 2.82Å
291K94.6Very high93.8Very high175 Ų17568.7 Ų68.776%0.76135%0.345SS*.THydrogen-bonded Turntrans-73.9-11.8175.7-65.4175.8-176.2177.70115.1E287 M289E287-K291 WeakPolarHBondContact O-CG 3.38Å; M289-K291 PolarHBondContact O-N 3.46Å; M289-K291 VanDerWaalsContact O-N 3.16Å
292K95.1Very high93.1Very high151 Ų15166.3 Ų66.366%0.65734%0.343SS*.THydrogen-bonded Turntrans-108.2-32.6-178.3-74.8-168.9171.7-154.60113.3M289 D290M289-K292 HydrophobicContact CE-CD 4.07Å; M289-K292 WeakPolarHBondContact O-CA 3.34Å; M289-K292 PolarHBondContact O-N 3.16Å; D290-K292 VanDerWaalsContact C-N 3.29Å; D290-K292 PolarHBondContact O-N 2.82Å
293M95.2Very high92Very high16 Ų1669.9 Ų69.98%0.07937%0.369CS..SBendtrans-67152.2179.6-68.2174.381.400110.7D109 A111 L126 R128 M289D109-M293 HydrophobicContact CB-CE 4.33Å; D109-M293 WeakPolarHBondContact O-CE 3.45Å; D109-M293 WeakPolarHBondContact OD2-CA 3.25Å; D109-M293 WeakPolarHBondContact OD2-CB 3.46Å; A111-M293 HydrophobicContact CB-CE 4.14Å; A111-M293 HydrophobicContact CB-CG 4.01Å; A111-M293 HydrophobicContact CB-SD 3.66Å; L126-M293 HydrophobicContact CB-CE 4.29Å; L126-M293 HydrophobicContact CB-SD 3.99Å; L126-M293 HydrophobicContact CD1-SD 4.47Å; R128-M293 HydrophobicContact CB-CE 3.86Å; M289-M293 HydrophobicContact CB-SD 4.42Å; M289-M293 WeakPolarHBondContact O-CG 3.22Å; M289-M293 PolarHBondContact O-N 2.8Å
294L94.9Very high90.8Very high92 Ų9271.4 Ų71.448%0.48238%0.381SS..PPolyproline II helixtrans-54.7147.4174-63.2176000110.9I108 D109 R128I108-L294 HydrophobicContact CG1-CD1 4.43Å; D109-L294 HydrophobicContact CB-CB 4.02Å; D109-L294 HydrophobicContact CB-CD1 4.26Å; D109-L294 HydrophobicContact CB-CG 4.24Å; D109-L294 PolarHBondContact OD2-N 3.35Å; R128-L294 WeakPolarHBondContact CG-O 3.36Å; R128-L294 PolarHBondContact NE-O 2.72Å
295P93.8Very high89.8Confident96 Ų9670.2 Ų70.262%0.62337%0.368SS*.PPolyproline II helixtrans-71.2155.4169.831.3-34.8000110.8
296S92.7Very high88Confident25 Ų2569.8 Ų69.818%0.17537%0.368CS..PPolyproline II helixtrans-64.5151.2164.6-56.90000110.6N65 L129 M130N65-S296 WeakPolarHBondContact CB-OG 3.41Å; N65-S296 PolarHBondContact ND2-OG 2.86Å; L129-S296 WeakPolarHBondContact O-CB 3.49Å; L129-S296 PolarHBondContact O-OG 3.06Å; M130-S296 WeakPolarHBondContact O-CB 3.07Å
297K92.4Very high86Confident146 Ų14671.7 Ų71.764%0.63538%0.377SS*.SBendtrans-78.5-40.2-177.8-65.9-178.8-179.7173.60112.4I108 M130I108-K297 HydrophobicContact CD1-CD 4.28Å; I108-K297 HydrophobicContact CD1-CG 3.88Å; M130-K297 HydrophobicContact CG-CD 3.87Å; M130-K297 HydrophobicContact CG-CG 4.25Å; M130-K297 PolarHBondContact O-N 2.87Å; M130-K297 HydrophobicContact SD-CD 4.08Å
298D91.5Very high83.6Confident83 Ų8374.1 Ų74.144%0.44438%0.384SS..EExtended strand (participates in β ladder)trans-152.4-170-173.355.845.6000110.6S131 G132S131-D298 CarbonylContact C-O 3.57Å; S131-D298 WeakPolarHBondContact CA-O 3.45Å; S131-D298 WeakPolarHBondContact CA-OD1 3.23Å; S131-D298 WeakPolarHBondContact CB-OD1 3.12Å; S131-D298 PolarHBondContact OG-OD1 2.79Å; G132-D298 PolarHBondContact N-O 3.33Å
299N91.9Very high81.3Confident94 Ų9469.6 Ų69.650%0.50337%0.366SS..EExtended strand (participates in β ladder)trans-128.9140174.8-60.1-59.9000109.4I63I63-N299 HydrophobicContact CD1-CB 3.92Å; I63-N299 VanDerWaalsContact CD1-CG 3.41Å; I63-N299 WeakPolarHBondContact CD1-OD1 3.06Å
300L87.1Confident79.1Confident35 Ų3571.2 Ų71.218%0.18338%0.377CS..  trans-65.6141.5172.9-70.5-176.1000110.8T103 I105 G132 P134 I305T103-L300 HydrophobicContact CG2-CD1 3.7Å; I105-L300 HydrophobicContact CD1-CD1 3.5Å; I105-L300 VanDerWaalsContact CD1-CD1 3.5Å; I105-L300 HydrophobicContact CG1-CD1 3.93Å; G132-L300 PolarHBondContact O-N 3.25Å; P134-L300 WeakPolarHBondContact CD-O 3.38Å; P134-L300 WeakPolarHBondContact CG-O 3.26Å; L300-I305 HydrophobicContact CD1-CD1 4.08Å
301P82.7Confident76.9Confident79 Ų7976.8 Ų76.851%0.51340%0.402SS..  trans-69.2143.7167.329.9-33.5000109.7S303 S304P301-S303 PolarHBondContact O-N 3.03Å; P301-S303 VanDerWaalsContact O-N 3.09Å; P301-S304 WeakPolarHBondContact CD-OG 3.4Å; P301-S304 WeakPolarHBondContact O-CB 3.49Å; P301-S304 PolarHBondContact O-N 3.09Å; P301-S304 PolarHBondContact O-OG 3.36Å
302A80.5Confident74.6Confident45 Ų4572.9 Ų72.937%0.37239%0.393SS..G310 helixtrans-57.3-29.5-178.100000113.5P134 T136 S304 I305P134-A302 HydrophobicContact CG-CB 4.3Å; T136-A302 HydrophobicContact CG2-CB 4.23Å; A302-S304 PolarHBondContact O-N 2.75Å; A302-I305 PolarHBondContact O-N 2.9Å
303S72.2Confident72.2Confident90 Ų9068.5 Ų68.563%0.62938%0.375SS*.G310 helixtrans-67.5-16.1174.2520000115P301P301-S303 PolarHBondContact O-N 3.03Å; P301-S303 VanDerWaalsContact O-N 3.09Å
304S72.5Confident69.9Low41 Ų4171.8 Ų71.829%0.28739%0.388SS..G310 helixtrans-88.3-5.9175.169.50000113.7T103 P301 A302 H306T103-S304 WeakPolarHBondContact CG2-O 3.31Å; T103-S304 PolarHBondContact OG1-O 3.26Å; P301-S304 WeakPolarHBondContact CD-OG 3.4Å; P301-S304 WeakPolarHBondContact O-CB 3.49Å; P301-S304 PolarHBondContact O-N 3.09Å; P301-S304 PolarHBondContact O-OG 3.36Å; A302-S304 PolarHBondContact O-N 2.75Å; S304-H306 PolarHBondContact O-N 2.97Å
305I74.1Confident67.8Low0 Ų071.7 Ų71.70%039%0.388CS..SBendtrans-75.6103169.7-57.1-51.4000107.8V92 T103 V133 P134 T136 T139 L300 A302 E307 Y308V92-I305 HydrophobicContact CG2-CD1 4.14Å; T103-I305 HydrophobicContact CG2-CD1 4.13Å; T103-I305 WeakPolarHBondContact OG1-CA 3.27Å; V133-I305 HydrophobicContact CG1-CD1 4.08Å; P134-I305 HydrophobicContact CG-CD1 4.33Å; P134-I305 HydrophobicContact CG-CG1 3.99Å; T136-I305 HydrophobicContact CG2-CB 4.38Å; T136-I305 HydrophobicContact CG2-CG1 4.16Å; T139-I305 HydrophobicContact CG2-CG2 3.66Å; L300-I305 HydrophobicContact CD1-CD1 4.08Å; A302-I305 PolarHBondContact O-N 2.9Å; I305-E307 VanDerWaalsContact C-N 3.31Å; I305-E307 PolarHBondContact O-N 3.15Å; I305-Y308 PolarHBondContact O-N 2.63Å
306H58.1Low65.7Low40 Ų4071.4 Ų71.419%0.18538%0.381CS..THydrogen-bonded Turntrans-77.783.4-176.7-178.263.1000110.5D101 T103 S304D101-H306 VanDerWaalsContact C-CD2 3.49Å; D101-H306 WeakPolarHBondContact CB-CE1 3.48Å; D101-H306 WeakPolarHBondContact CB-ND1 3.44Å; D101-H306 WeakPolarHBondContact O-CB 3.3Å; D101-H306 IonicContact OD2-CE1 2.66Å; T103-H306 WeakPolarHBondContact OG1-CB 3.47Å; T103-H306 PolarHBondContact OG1-N 3.27Å; S304-H306 PolarHBondContact O-N 2.97Å
307E55.5Low63.3Low41 Ų4176.1 Ų76.119%0.19240%0.399CS..THydrogen-bonded Turn-142.938.7118.1-160111.647.300110.3K28 H29 I305 L309K28-E307 WeakPolarHBondContact CE-OE1 3.03Å; K28-E307 WeakPolarHBondContact CE-OE2 3.27Å; K28-E307 IonicContact NZ-OE1 2.72Å; K28-E307 IonicContact NZ-OE2 2.82Å; K28-E307 PolarHBondContact NZ-OE2 2.94Å; H29-E307 WeakPolarHBondContact CE1-CB 3.19Å; H29-E307 VanDerWaalsContact CE1-CG 3.46Å; H29-E307 WeakPolarHBondContact CE1-CG 3.35Å; H29-E307 IonicContact CE1-OE1 2.77Å; H29-E307 PolarHBondContact CE1-OE1 2.73Å; H29-E307 VanDerWaalsContact NE2-CG 3.32Å; H29-E307 WeakPolarHBondContact NE2-CG 3.49Å; H29-E307 IonicContact NE2-OE1 3.77Å; H29-E307 PolarHBondContact NE2-OE1 3.28Å; I305-E307 VanDerWaalsContact C-N 3.31Å; I305-E307 PolarHBondContact O-N 3.15Å; E307-L309 PolarHBondContact O-N 3.07Å
308Y45.2Very low61.2Low110 Ų11076 Ų7643%0.43140%0.404SS..SBendtrans-65.691.2161.1-107.8-89.1000108.8I305 K314I305-Y308 PolarHBondContact O-N 2.63Å; Y308-K314 WeakPolarHBondContact O-CE 3.49Å
309L47.1Very low59Low31 Ų3177 Ų7716%0.16241%0.41CS..  trans72.5122.6156.4-47.6171000114.1E307 E313 K314 F317E307-L309 PolarHBondContact O-N 3.07Å; L309-E313 HydrophobicContact CB-CB 3.46Å; L309-E313 VanDerWaalsContact CB-CB 3.46Å; L309-E313 HydrophobicContact CD2-CB 3.65Å; L309-E313 HydrophobicContact CD2-CG 4.49Å; L309-E313 HydrophobicContact CG-CB 4.05Å; L309-K314 HydrophobicContact CB-CB 4.43Å; L309-K314 HydrophobicContact CB-CG 3.7Å; L309-K314 HydrophobicContact CD1-CG 4.44Å; L309-K314 WeakPolarHBondContact O-CE 3.47Å; L309-F317 HydrophobicContact CD1-CB 3.73Å; L309-F317 HydrophobicContact CD1-CD2 3.95Å; L309-F317 HydrophobicContact CD1-CG 3.99Å
310T49.6Very low56.5Low61 Ų6180.3 Ų80.337%0.37442%0.419SS..  trans-49.9163.8157.658.50000110.3T312 E313 K314T310-T312 PolarHBondContact O-N 2.75Å; T310-T312 VanDerWaalsContact O-N 3.15Å; T310-E313 WeakPolarHBondContact CB-OE2 3.06Å; T310-E313 VanDerWaalsContact CG2-OE2 3.23Å; T310-E313 WeakPolarHBondContact CG2-OE2 2.98Å; T310-E313 PolarHBondContact N-OE2 2.91Å; T310-E313 CarbonylContact O-C 3.39Å; T310-E313 PolarHBondContact O-N 3.19Å; T310-E313 WeakPolarHBondContact OG1-CG 3.5Å; T310-E313 PolarHBondContact OG1-N 2.97Å; T310-E313 PolarHBondContact OG1-OE2 3.27Å; T310-K314 PolarHBondContact O-N 2.66Å
311Q48.4Very low54.1Low162 Ų16283.8 Ų83.876%0.75745%0.447SS*.Hα-helixtrans-54.6-37.4174.8-76.4-165.3-7.800112.1K314 I315Q311-K314 PolarHBondContact O-N 2.7Å; Q311-I315 WeakPolarHBondContact O-CB 3.27Å; Q311-I315 WeakPolarHBondContact O-CD1 3.29Å; Q311-I315 WeakPolarHBondContact O-CG1 3.42Å; Q311-I315 PolarHBondContact O-N 2.85Å
312T45.8Very low51.9Low92 Ų9286.2 Ų86.256%0.56446%0.46SS*.Hα-helixtrans-56.3-49.6172.2-45.50000112.1T310 I315 N316T310-T312 PolarHBondContact O-N 2.75Å; T310-T312 VanDerWaalsContact O-N 3.15Å; T312-I315 WeakPolarHBondContact O-CB 3.3Å; T312-I315 PolarHBondContact O-N 2.81Å; T312-N316 PolarHBondContact O-N 2.79Å; T312-N316 PolarHBondContact O-ND2 2.76Å; T312-N316 PolarHBondContact O-OD1 3.35Å
313E45.7Very low49.6Very low60 Ų6088.1 Ų88.128%0.2848%0.475SS..Hα-helixtrans-72.2-34.1-179.8-69.2160123.500112.1L309 T310 I315 N316 F317L309-E313 HydrophobicContact CB-CB 3.46Å; L309-E313 VanDerWaalsContact CB-CB 3.46Å; L309-E313 HydrophobicContact CD2-CB 3.65Å; L309-E313 HydrophobicContact CD2-CG 4.49Å; L309-E313 HydrophobicContact CG-CB 4.05Å; T310-E313 WeakPolarHBondContact CB-OE2 3.06Å; T310-E313 VanDerWaalsContact CG2-OE2 3.23Å; T310-E313 WeakPolarHBondContact CG2-OE2 2.98Å; T310-E313 PolarHBondContact N-OE2 2.91Å; T310-E313 CarbonylContact O-C 3.39Å; T310-E313 PolarHBondContact O-N 3.19Å; T310-E313 WeakPolarHBondContact OG1-CG 3.5Å; T310-E313 PolarHBondContact OG1-N 2.97Å; T310-E313 PolarHBondContact OG1-OE2 3.27Å; E313-I315 VanDerWaalsContact C-N 3.32Å; E313-I315 PolarHBondContact O-N 3.31Å; E313-N316 PolarHBondContact O-N 2.96Å; E313-F317 PolarHBondContact O-N 3.29Å
314K45.5Very low47.4Very low84 Ų8488.6 Ų88.637%0.36548%0.484SS..Hα-helixtrans-62-42.2172.7-74.1-176.5-178.3172.40110.2D101 Y308 L309 T310 Q311 F317 L318D101-K314 IonicContact OD2-NZ 2.85Å; D101-K314 PolarHBondContact OD2-NZ 3.08Å; Y308-K314 WeakPolarHBondContact O-CE 3.49Å; L309-K314 HydrophobicContact CB-CB 4.43Å; L309-K314 HydrophobicContact CB-CG 3.7Å; L309-K314 HydrophobicContact CD1-CG 4.44Å; L309-K314 WeakPolarHBondContact O-CE 3.47Å; T310-K314 PolarHBondContact O-N 2.66Å; Q311-K314 PolarHBondContact O-N 2.7Å; K314-F317 PolarHBondContact O-N 3.33Å; K314-L318 PolarHBondContact O-N 2.79Å
315I51.3Low45.4Very low91 Ų9192.8 Ų92.847%0.46751%0.508SS..Hα-helixtrans-63.3-44.9173.1-71165000110.3Q311 T312 E313 F317 L318 N319Q311-I315 WeakPolarHBondContact O-CB 3.27Å; Q311-I315 WeakPolarHBondContact O-CD1 3.29Å; Q311-I315 WeakPolarHBondContact O-CG1 3.42Å; Q311-I315 PolarHBondContact O-N 2.85Å; T312-I315 WeakPolarHBondContact O-CB 3.3Å; T312-I315 PolarHBondContact O-N 2.81Å; E313-I315 VanDerWaalsContact C-N 3.32Å; E313-I315 PolarHBondContact O-N 3.31Å; I315-F317 VanDerWaalsContact C-N 3.34Å; I315-F317 PolarHBondContact O-N 3.32Å; I315-L318 PolarHBondContact O-N 2.63Å; I315-N319 WeakPolarHBondContact CG2-ND2 3.42Å; I315-N319 VanDerWaalsContact O-CB 3.23Å; I315-N319 WeakPolarHBondContact O-CB 3.46Å; I315-N319 PolarHBondContact O-N 2.79Å
316N49.7Very low43.1Very low90 Ų9097.7 Ų97.748%0.48155%0.549SS..Hα-helixtrans-66.1-31.6179.2-69.1-15.9000113.5T312 E313T312-N316 PolarHBondContact O-N 2.79Å; T312-N316 PolarHBondContact O-ND2 2.76Å; T312-N316 PolarHBondContact O-OD1 3.35Å; E313-N316 PolarHBondContact O-N 2.96Å
317F43.6Very low41.9Very low124 Ų124103.5 Ų103.554%0.54458%0.576SS.*Hα-helixtrans-75.9-32.3177.6-146.1-82.8000112.4L309 E313 K314 I315L309-F317 HydrophobicContact CD1-CB 3.73Å; L309-F317 HydrophobicContact CD1-CD2 3.95Å; L309-F317 HydrophobicContact CD1-CG 3.99Å; E313-F317 PolarHBondContact O-N 3.29Å; K314-F317 PolarHBondContact O-N 3.33Å; I315-F317 VanDerWaalsContact C-N 3.34Å; I315-F317 PolarHBondContact O-N 3.32Å
318L48.3Very low40.7Very low144 Ų144110.6 Ų110.675%0.75461%0.606SS**Hα-helixtrans-77.7-32.8172.9-75.5163.9000112.8K314 I315 K320K314-L318 PolarHBondContact O-N 2.79Å; I315-L318 PolarHBondContact O-N 2.63Å; L318-K320 VanDerWaalsContact C-N 3.34Å; L318-K320 PolarHBondContact O-N 3.41Å
319N44.9Very low40.4Very low104 Ų104109.5 Ų109.556%0.55662%0.62SS**  trans-91.130-175.1-71.4-14.8000114.8I315 S321I315-N319 WeakPolarHBondContact CG2-ND2 3.42Å; I315-N319 VanDerWaalsContact O-CB 3.23Å; I315-N319 WeakPolarHBondContact O-CB 3.46Å; I315-N319 PolarHBondContact O-N 2.79Å; N319-S321 PolarHBondContact O-N 3.05Å
320K37.9Very low40.7Very low163 Ų163114.8 Ų114.871%0.70964%0.644SS**THydrogen-bonded Turntrans-7238175.1-88.5-175.3174.8173.20114.4L318L318-K320 VanDerWaalsContact C-N 3.34Å; L318-K320 PolarHBondContact O-N 3.41Å
321S37.1Very low41.5Very low108 Ų108119 Ų11976%0.75566%0.657SS**THydrogen-bonded Turntrans-168.841.5176.254.60000117N319N319-S321 PolarHBondContact O-N 3.05Å
322V37.7Very low42.9Very low130 Ų130114.6 Ų114.679%0.78864%0.636SS**  trans-130.8134.5163.2-178.50000112
323A31.2Very low44.8Very low84 Ų84115.2 Ų115.269%0.69463%0.632SS**  trans-72.9159.8-176.100000113.4V325A323-V325 PolarHBondContact O-N 2.8Å
324A26.8Very low47.2Very low100 Ų100114.3 Ų114.383%0.82663%0.632SS**  trans-62.6128.2175.600000111.5
325V30.1Very low49.5Very low129 Ų129110.3 Ų110.378%0.78261%0.614SS**  trans-110.1124.6169.9-179.80000108.1A323 Q327A323-V325 PolarHBondContact O-N 2.8Å; V325-Q327 PolarHBondContact O-N 2.68Å
326A26.1Very low51.5Low104 Ų104108.3 Ų108.386%0.8661%0.607SS**PPolyproline II helixtrans-69.5116.5174.100000109.6
327Q31.6Very low53.5Low161 Ų161105.1 Ų105.175%0.75259%0.591SS**PPolyproline II helixtrans-88.3134.7-179.4-141.3168.1-200110.3V325V325-Q327 PolarHBondContact O-N 2.68Å
328K30.9Very low55.6Low191 Ų19199.5 Ų99.583%0.8357%0.567SS**PPolyproline II helixtrans-60.2154.5170.9-77.8176.6172.9176.30109.8E330K328-E330 PolarHBondContact O-N 2.68Å
329A38.5Very low57.3Low87 Ų8798.6 Ų98.672%0.71957%0.569SS**  trans-65.991.7173.600000110.8
330E54.4Low59Low141 Ų14199.7 Ų99.766%0.65957%0.569SS**PPolyproline II helixtrans-72135.5165.4-71.2-178.9153.900109.2K328K328-E330 PolarHBondContact O-N 2.68Å
331F65.7Low61.2Low150 Ų15094.1 Ų94.166%0.65855%0.545SS*.PPolyproline II helixtrans-77132.9174.6-73.5-86.1000109.9E333 N395F331-E333 PolarHBondContact O-N 3.41Å; F331-N395 WeakPolarHBondContact CA-OD1 3.43Å
332F77.5Confident63.4Low70 Ų7092 Ų9231%0.30753%0.528SS..PPolyproline II helixtrans-72.9120.4175.9-70.2-86000110.9N395 F471 K476F332-N395 HydrophobicContact CD2-CB 4.43Å; F332-N395 PolarHBondContact N-OD1 2.85Å; F332-F471 HydrophobicContact CB-CB 3.92Å; F332-F471 HydrophobicContact CB-CD2 3.88Å; F332-F471 HydrophobicContact CB-CG 4.3Å; F332-F471 HydrophobicContact CD1-CB 4.39Å; F332-F471 HydrophobicContact CD2-CB 3.49Å; F332-F471 VanDerWaalsContact CD2-CB 3.49Å; F332-F471 HydrophobicContact CE2-CB 4.03Å; F332-F471 WeakPolarHBondContact CE2-O 3.33Å; F332-F471 HydrophobicContact CG-CB 3.69Å; F332-K476 HydrophobicContact CD1-CD 4.24Å; F332-K476 HydrophobicContact CD1-CG 4.49Å
333E87.3Confident65.7Low105 Ų10586.9 Ų86.949%0.49150%0.497SS..PPolyproline II helixtrans-75.2146.4172.4-58.5-156.4116.200112.4F331 V336 K582F331-E333 PolarHBondContact O-N 3.41Å; E333-V336 HydrophobicContact CB-CG2 4.13Å; E333-K582 IonicContact OE1-NZ 3.1Å; E333-K582 PolarHBondContact OE1-NZ 2.83Å; E333-K582 WeakPolarHBondContact OE2-CE 3.27Å; E333-K582 IonicContact OE2-NZ 3.17Å; E333-K582 PolarHBondContact OE2-NZ 2.93Å
334C94.6Very high67.7Low40 Ų4085.9 Ų85.927%0.2748%0.482SS..THydrogen-bonded Turntrans-64.9151.216968.20000111.7V336 P477 C479C334-V336 PolarHBondContact O-N 2.89Å; C334-V336 VanDerWaalsContact O-N 3.1Å; C334-P477 CarbonylContact C-O 3.57Å; C334-P477 WeakPolarHBondContact CA-O 3.32Å; C334-P477 HydrophobicContact CB-CG 4.11Å; C334-C479 HydrophobicContact CB-CB 3.99Å; C334-C479 WeakPolarHBondContact CB-SG 3.44Å; C334-C479 PolarHBondContact O-SG 3.32Å; C334-C479 WeakPolarHBondContact SG-CA 3.45Å; C334-C479 WeakPolarHBondContact SG-CB 3.46Å; C334-C479 CovalentContact SG-SG 2.05Å; C334-C479 PolarHBondContact SG-SG 2.82Å
335G94.4Very high69.6Low0 Ų083.8 Ų83.80%046%0.456CS..THydrogen-bonded Turntrans66.113.4170.200000115.5P477 W583G335-P477 PolarHBondContact N-O 2.84Å; G335-W583 VanDerWaalsContact CA-O 3.31Å; G335-W583 WeakPolarHBondContact CA-O 3.19Å; G335-W583 PolarHBondContact O-N 2.92Å
336V93.8Very high70.6Confident50 Ų5082 Ų8230%0.30345%0.449SS..  trans-116.699.2179.2-178.30000110E333 C334 K476 K582E333-V336 HydrophobicContact CB-CG2 4.13Å; C334-V336 PolarHBondContact O-N 2.89Å; C334-V336 VanDerWaalsContact O-N 3.1Å; V336-K476 WeakPolarHBondContact O-CD 3.14Å; V336-K476 PolarHBondContact O-NZ 2.92Å; V336-K582 HydrophobicContact CG2-CD 4.33Å; V336-K582 HydrophobicContact CG2-CG 3.97Å
337P91.4Very high71.6Confident23 Ų2379.1 Ų79.115%0.14942%0.421CS..  trans-63.6163.3175.729.7-36.1000111.3I343 P365P337-I343 HydrophobicContact CB-CD1 4.4Å; P337-I343 HydrophobicContact CB-CG1 4.48Å; P337-I343 HydrophobicContact CG-CD1 3.97Å; P337-I343 HydrophobicContact CG-CG1 4.19Å; P337-P365 HydrophobicContact CB-CG 4.37Å
338S87.4Confident72Confident6 Ų677.1 Ų77.14%0.04241%0.414CS..  trans-65.9138.9175.3-179.60000110.8K340 F341 E473S338-K340 PolarHBondContact O-N 3.17Å; S338-K340 VanDerWaalsContact O-N 3.07Å; S338-K340 PolarHBondContact OG-N 3.47Å; S338-F341 CarbonylContact O-C 3.58Å; S338-F341 VanDerWaalsContact O-C 3.28Å; S338-F341 PolarHBondContact O-N 2.88Å; S338-E473 WeakPolarHBondContact CB-O 3.43Å
339P84.2Confident72.2Confident124 Ų12470.5 Ų70.581%0.80539%0.39SS*.THydrogen-bonded Turntrans-55.9-22.5170.8-26.235.4000114.1F341P339-F341 VanDerWaalsContact C-N 3.32Å
340K80.7Confident72Confident128 Ų12869.6 Ų69.656%0.55738%0.376SS*.THydrogen-bonded Turntrans-71.5-24.1173.7-62.7176.4-177.9167.70113.5S338 P342 E473S338-K340 PolarHBondContact O-N 3.17Å; S338-K340 VanDerWaalsContact O-N 3.07Å; S338-K340 PolarHBondContact OG-N 3.47Å; K340-P342 VanDerWaalsContact C-CD 3.5Å; K340-E473 WeakPolarHBondContact CD-OE2 3.1Å; K340-E473 VanDerWaalsContact CE-OE1 3.32Å; K340-E473 WeakPolarHBondContact CE-OE1 3.27Å; K340-E473 IonicContact NZ-OE1 2.85Å; K340-E473 PolarHBondContact NZ-OE1 3.25Å; K340-E473 IonicContact NZ-OE2 3.47Å; K340-E473 PolarHBondContact NZ-OE2 2.98Å
341F84.5Confident70.9Confident46 Ų4667 Ų6720%0.20237%0.367CS..SBendtrans-129.266-175.4-50.3-60.4000109.7S338 P339 H362 S363 E473 I474S338-F341 CarbonylContact O-C 3.58Å; S338-F341 VanDerWaalsContact O-C 3.28Å; S338-F341 PolarHBondContact O-N 2.88Å; P339-F341 VanDerWaalsContact C-N 3.32Å; F341-H362 HydrophobicContact CB-CB 4.23Å; F341-H362 HydrophobicContact CD1-CB 4.24Å; F341-H362 HydrophobicContact CD2-CB 3.86Å; F341-H362 AromaticContact CE1-CD2 3.9Å; F341-H362 HydrophobicContact CE2-CB 4.31Å; F341-H362 HydrophobicContact CG-CB 3.84Å; F341-H362 AromaticContact CZ-CD2 3.87Å; F341-S363 WeakPolarHBondContact O-CA 3.37Å; F341-E473 HydrophobicContact CE2-CB 4.3Å; F341-I474 HydrophobicContact CD2-CG2 3.99Å; F341-I474 HydrophobicContact CE2-CG2 3.52Å; F341-I474 HydrophobicContact CZ-CG2 4.23Å
342P83.2Confident69.5Low62 Ų6263.7 Ų63.740%0.40335%0.35SS..  trans-66.1146.7-177.229.2-35.9000111.5K340 T344 Q360K340-P342 VanDerWaalsContact C-CD 3.5Å; P342-T344 PolarHBondContact O-N 3.33Å; P342-Q360 PolarHBondContact O-OE1 2.57Å
343I84.6Confident68Low24 Ų2460.8 Ų60.812%0.12334%0.337CS..  trans-78117.4171.2-68170.6000109P337 M345 S363 L364 W366 I494 M531 W583P337-I343 HydrophobicContact CB-CD1 4.4Å; P337-I343 HydrophobicContact CB-CG1 4.48Å; P337-I343 HydrophobicContact CG-CD1 3.97Å; P337-I343 HydrophobicContact CG-CG1 4.19Å; I343-M345 HydrophobicContact CG2-SD 4.33Å; I343-S363 WeakPolarHBondContact CD1-O 3.07Å; I343-S363 WeakPolarHBondContact CG1-O 3.24Å; I343-L364 HydrophobicContact CD1-CD2 3.66Å; I343-L364 HydrophobicContact CG1-CD2 4Å; I343-W366 HydrophobicContact CD1-CH2 3.53Å; I343-W366 HydrophobicContact CD1-CZ2 3.66Å; I343-I494 HydrophobicContact CG2-CD1 3.49Å; I343-I494 VanDerWaalsContact CG2-CD1 3.49Å; I343-M531 HydrophobicContact CG2-CE 4.19Å; I343-W583 HydrophobicContact CB-CZ2 4.45Å; I343-W583 HydrophobicContact CD1-CD2 4.36Å; I343-W583 HydrophobicContact CD1-CG 4.4Å; I343-W583 HydrophobicContact CD1-CZ2 4.33Å; I343-W583 HydrophobicContact CG2-CZ2 4.02Å
344T73.5Confident65.8Low62 Ų6256.9 Ų56.938%0.3832%0.322SS..  trans-93.6105.6178.511.20000110.5P342 S346 W357 Q360P342-T344 PolarHBondContact O-N 3.33Å; T344-S346 VanDerWaalsContact C-N 3.31Å; T344-S346 PolarHBondContact O-N 2.86Å; T344-W357 PolarHBondContact O-NE1 2.65Å; T344-Q360 PolarHBondContact OG1-OE1 3.09Å
345M67.3Low63.6Low57 Ų5755.5 Ų55.528%0.28131%0.314SS..  trans-78.4-9.2179.7-69.3-66.1-84.200114.2I343 E492 I494 I533 W583I343-M345 HydrophobicContact CG2-SD 4.33Å; M345-E492 HydrophobicContact CE-CB 4.47Å; M345-I494 HydrophobicContact CE-CG1 4.14Å; M345-I494 HydrophobicContact SD-CD1 3.58Å; M345-I494 VanDerWaalsContact SD-CD1 3.58Å; M345-I494 HydrophobicContact SD-CG1 3.57Å; M345-I494 VanDerWaalsContact SD-CG1 3.57Å; M345-I533 HydrophobicContact CB-CD1 3.98Å; M345-I533 HydrophobicContact CE-CD1 3.4Å; M345-I533 VanDerWaalsContact CE-CD1 3.4Å; M345-I533 HydrophobicContact CE-CG1 3.79Å; M345-I533 WeakPolarHBondContact O-CD1 3.13Å; M345-I533 HydrophobicContact SD-CD1 3.8Å; M345-I533 HydrophobicContact SD-CG1 4.17Å; M345-W583 HydrophobicContact CE-CH2 3.97Å; M345-W583 HydrophobicContact CG-CH2 4.45Å; M345-W583 HydrophobicContact SD-CH2 3.67Å; M345-W583 HydrophobicContact SD-CZ2 4.32Å
346S51.6Low61.8Low90 Ų9055.5 Ų55.563%0.62931%0.314SS*.SBendtrans-116.1120.2-178.1-175.50000109.8T344 I348T344-S346 VanDerWaalsContact C-N 3.31Å; T344-S346 PolarHBondContact O-N 2.86Å; S346-I348 PolarHBondContact O-N 2.76Å
347P46.7Very low60.4Low44 Ų4454 Ų5429%0.28630%0.303SS..  trans-69.5123.2176.326.1-30.8000109.9T349 W357P347-T349 VanDerWaalsContact CB-O 3.24Å; P347-T349 WeakPolarHBondContact CB-O 3.32Å; P347-W357 HydrophobicContact CB-CD2 3.98Å; P347-W357 HydrophobicContact CB-CE3 3.88Å; P347-W357 HydrophobicContact CB-CG 4.31Å; P347-W357 HydrophobicContact CB-CZ3 4.35Å; P347-W357 HydrophobicContact CG-CE3 4.07Å; P347-W357 HydrophobicContact CG-CZ3 4.06Å
348I39.2Very low59.4Low119 Ų11955.4 Ų55.461%0.6131%0.311SS*.SBendtrans-74.2-24.1161-62.5175.8000109.5S346S346-I348 PolarHBondContact O-N 2.76Å
349T36.2Very low58.8Low52 Ų5255.2 Ų55.232%0.31931%0.31SS..SBendtrans-152.5175.7178.659.80000114.1T98 E191 P347T98-T349 HydrophobicContact CG2-CG2 3.69Å; E191-T349 WeakPolarHBondContact OE1-CB 2.92Å; E191-T349 WeakPolarHBondContact OE1-CG2 3.08Å; E191-T349 PolarHBondContact OE1-OG1 2.9Å; E191-T349 PolarHBondContact OE2-OG1 3Å; P347-T349 VanDerWaalsContact CB-O 3.24Å; P347-T349 WeakPolarHBondContact CB-O 3.32Å
350T33.8Very low58.5Low69 Ų6953 Ų5342%0.42329%0.289SS..  trans-142.6155-173.465.10000110.9L188L188-T350 WeakPolarHBondContact CD2-O 3Å
351N32.2Very low58.5Low86 Ų8651.1 Ų51.146%0.4628%0.281SS..  cis-142148.28.2-105.8-28.7000110.1G355 G356N351-G355 VanDerWaalsContact OD1-CA 3.3Å; N351-G355 WeakPolarHBondContact OD1-CA 3.31Å; N351-G355 PolarHBondContact OD1-O 2.98Å; N351-G356 CarbonylContact C-O 3.53Å; N351-G356 VanDerWaalsContact C-O 3.3Å; N351-G356 WeakPolarHBondContact CA-O 3.37Å; N351-G356 PolarHBondContact OD1-N 2.89Å; N351-G356 PolarHBondContact OD1-O 2.69Å
352R36.5Very low58.6Low81 Ų8149.4 Ų49.431%0.30627%0.273SS..SBendtrans-158.611.2162.5-118.4-179.5-60.5162.710.9122.5G356 T501 N525 D528 A530R352-G356 PolarHBondContact N-O 3.41Å; R352-T501 HydrophobicContact CG-CG2 3.76Å; R352-N525 WeakPolarHBondContact CD-O 3.38Å; R352-N525 PolarHBondContact NH1-O 2.83Å; R352-D528 IonicContact CZ-OD2 3.33Å; R352-D528 IonicContact NH1-OD2 2.73Å; R352-D528 PolarHBondContact NH1-OD2 3.26Å; R352-D528 IonicContact NH2-OD2 3.68Å; R352-A530 HydrophobicContact CB-CB 4.2Å; R352-A530 VanDerWaalsContact O-CB 3.3Å; R352-A530 WeakPolarHBondContact O-CB 3.47Å
353I44.2Very low58.9Low9 Ų946.5 Ų46.55%0.04625%0.254CS..SBendtrans-103.7177140.4-75.4-170.6000105.7G355 G356 A530 T532 G565I353-G355 PolarHBondContact O-N 2.84Å; I353-G356 PolarHBondContact O-N 3.08Å; I353-A530 HydrophobicContact CD1-CB 4.36Å; I353-A530 WeakPolarHBondContact CD1-O 3.28Å; I353-A530 HydrophobicContact CG1-CB 3.64Å; I353-T532 HydrophobicContact CB-CG2 4.37Å; I353-T532 HydrophobicContact CG2-CG2 3.69Å; I353-G565 WeakPolarHBondContact CG2-O 3.48Å
354S42.4Very low59.3Low23 Ų2345.6 Ų45.616%0.16125%0.25CC..BIsolated β-bridgetrans-53116.6164.8-161.90000107.6G356 H563 R564 G565 G597S354-G356 PolarHBondContact O-N 2.96Å; S354-H563 WeakPolarHBondContact CB-O 3.28Å; S354-H563 PolarHBondContact OG-O 2.87Å; S354-R564 WeakPolarHBondContact O-CA 3.45Å; S354-G565 VanDerWaalsContact CB-O 3.24Å; S354-G565 WeakPolarHBondContact CB-O 3.16Å; S354-G565 PolarHBondContact N-O 3.4Å; S354-G565 PolarHBondContact O-N 2.85Å; S354-G597 WeakPolarHBondContact OG-CA 3.44Å
355G48.8Very low60.3Low11 Ų1142.8 Ų42.811%0.11323%0.233CC..THydrogen-bonded Turntrans548.2-170.200000119N351 I353 R564N351-G355 VanDerWaalsContact OD1-CA 3.3Å; N351-G355 WeakPolarHBondContact OD1-CA 3.31Å; N351-G355 PolarHBondContact OD1-O 2.98Å; I353-G355 PolarHBondContact O-N 2.84Å; G355-R564 WeakPolarHBondContact O-CG 3.34Å; G355-R564 PolarHBondContact O-NE 2.86Å
356G55.5Low61.7Low0 Ų040.1 Ų40.10%022%0.22CC..  trans-95.6-170.2-178.100000114.3N351 R352 I353 S354 M531 T532N351-G356 CarbonylContact C-O 3.53Å; N351-G356 VanDerWaalsContact C-O 3.3Å; N351-G356 WeakPolarHBondContact CA-O 3.37Å; N351-G356 PolarHBondContact OD1-N 2.89Å; N351-G356 PolarHBondContact OD1-O 2.69Å; R352-G356 PolarHBondContact N-O 3.41Å; I353-G356 PolarHBondContact O-N 3.08Å; S354-G356 PolarHBondContact O-N 2.96Å; G356-M531 CarbonylContact C-O 3.59Å; G356-M531 VanDerWaalsContact CA-O 3.26Å; G356-M531 WeakPolarHBondContact CA-O 3.39Å; G356-T532 WeakPolarHBondContact CA-OG1 3.18Å
357W64.3Low63.8Low19 Ų1936.1 Ų36.17%0.07219%0.191CC..EExtended strand (participates in β ladder)trans-134.8166.2179.555.598.4000112.4T344 P347 A359 A530 M531 I533T344-W357 PolarHBondContact O-NE1 2.65Å; P347-W357 HydrophobicContact CB-CD2 3.98Å; P347-W357 HydrophobicContact CB-CE3 3.88Å; P347-W357 HydrophobicContact CB-CG 4.31Å; P347-W357 HydrophobicContact CB-CZ3 4.35Å; P347-W357 HydrophobicContact CG-CE3 4.07Å; P347-W357 HydrophobicContact CG-CZ3 4.06Å; W357-A359 PolarHBondContact O-N 3.37Å; W357-A530 CarbonylContact O-C 3.59Å; W357-A530 WeakPolarHBondContact O-CA 3.24Å; W357-A530 WeakPolarHBondContact O-CB 3.35Å; W357-M531 HydrophobicContact CZ2-CE 3.95Å; W357-M531 PolarHBondContact N-O 3.08Å; W357-M531 PolarHBondContact O-N 3.33Å; W357-M531 VanDerWaalsContact O-O 3.07Å; W357-I533 HydrophobicContact CH2-CB 4.27Å; W357-I533 HydrophobicContact CH2-CD1 3.75Å; W357-I533 HydrophobicContact CH2-CG1 3.71Å; W357-I533 HydrophobicContact CZ2-CD1 4.28Å; W357-I533 HydrophobicContact CZ2-CG1 4.32Å
358T70.5Confident66.1Low51 Ų5134 Ų3431%0.31318%0.177SC..EExtended strand (participates in β ladder)trans-65.3128.8173.1-60.40000109.7D528T358-D528 HydrophobicContact CG2-CB 3.94Å
359A74.4Confident68.7Low3 Ų328.7 Ų28.73%0.02515%0.15CC..PPolyproline II helixtrans-66.3141.2177.800000110.2W357 K361 L364 Q428 L529 M531W357-A359 PolarHBondContact O-N 3.37Å; A359-K361 PolarHBondContact O-N 3.21Å; A359-L364 HydrophobicContact CB-CD1 3.93Å; A359-Q428 PolarHBondContact O-NE2 2.96Å; A359-L529 HydrophobicContact CB-CD2 4.33Å; A359-L529 HydrophobicContact CB-CG 4.1Å; A359-L529 PolarHBondContact N-O 3.48Å; A359-M531 HydrophobicContact CB-CB 4.3Å; A359-M531 HydrophobicContact CB-CG 3.88Å; A359-M531 HydrophobicContact CB-SD 3.84Å
360Q79.3Confident71.4Confident77 Ų7726.2 Ų26.236%0.3614%0.135SC..PPolyproline II helixtrans-58.4138.1173.6177.5172.7-2.300109.6P342 T344 H362 S363P342-Q360 PolarHBondContact O-OE1 2.57Å; T344-Q360 PolarHBondContact OG1-OE1 3.09Å; Q360-H362 PolarHBondContact O-N 2.83Å; Q360-S363 PolarHBondContact N-OG 2.94Å; Q360-S363 VanDerWaalsContact O-CB 3.23Å; Q360-S363 WeakPolarHBondContact O-CB 3.49Å; Q360-S363 PolarHBondContact O-N 2.94Å; Q360-S363 PolarHBondContact O-OG 3.42Å
361K80Confident74.1Confident89 Ų8923.7 Ų23.739%0.38712%0.119SC..THydrogen-bonded Turntrans-49.2124.5-176.9-160178.3-167.11730110.9A359 S363 Q428 E634A359-K361 PolarHBondContact O-N 3.21Å; K361-S363 PolarHBondContact O-N 2.66Å; K361-S363 VanDerWaalsContact O-N 3.16Å; K361-Q428 HydrophobicContact CG-CB 4.12Å; K361-Q428 HydrophobicContact CG-CG 4.12Å; K361-E634 VanDerWaalsContact CE-CD 3.48Å; K361-E634 WeakPolarHBondContact CE-OE1 3.38Å; K361-E634 WeakPolarHBondContact CE-OE2 3.27Å; K361-E634 IonicContact NZ-OE1 2.85Å; K361-E634 PolarHBondContact NZ-OE1 3.37Å; K361-E634 IonicContact NZ-OE2 3.63Å
362H86.9Confident76.8Confident10 Ų1019.6 Ų19.65%0.04610%0.097CC..THydrogen-bonded Turntrans62.46.7-177.9-44.4-52.8000117.3F341 Q360 L364 I474 E634F341-H362 HydrophobicContact CB-CB 4.23Å; F341-H362 HydrophobicContact CD1-CB 4.24Å; F341-H362 HydrophobicContact CD2-CB 3.86Å; F341-H362 AromaticContact CE1-CD2 3.9Å; F341-H362 HydrophobicContact CE2-CB 4.31Å; F341-H362 HydrophobicContact CG-CB 3.84Å; F341-H362 AromaticContact CZ-CD2 3.87Å; Q360-H362 PolarHBondContact O-N 2.83Å; H362-L364 PolarHBondContact O-N 3.33Å; H362-I474 HydrophobicContact CB-CB 3.86Å; H362-I474 HydrophobicContact CB-CG2 3.6Å; H362-I474 VanDerWaalsContact CG-CG2 3.43Å; H362-E634 IonicContact CD2-OE2 3.81Å; H362-E634 IonicContact CE1-OE2 3.1Å; H362-E634 IonicContact NE2-OE2 2.74Å; H362-E634 PolarHBondContact NE2-OE2 2.87Å
363S89.1Confident78.9Confident0 Ų017.6 Ų17.60%010%0.097CC..SBendtrans-66.3-22.8-179.162.20000113.9F341 I343 Q360 K361 P365F341-S363 WeakPolarHBondContact O-CA 3.37Å; I343-S363 WeakPolarHBondContact CD1-O 3.07Å; I343-S363 WeakPolarHBondContact CG1-O 3.24Å; Q360-S363 PolarHBondContact N-OG 2.94Å; Q360-S363 VanDerWaalsContact O-CB 3.23Å; Q360-S363 WeakPolarHBondContact O-CB 3.49Å; Q360-S363 PolarHBondContact O-N 2.94Å; Q360-S363 PolarHBondContact O-OG 3.42Å; K361-S363 PolarHBondContact O-N 2.66Å; K361-S363 VanDerWaalsContact O-N 3.16Å; S363-P365 WeakPolarHBondContact O-CD 3.46Å
364L92.9Very high80.2Confident6 Ų621 Ų213%0.03111%0.112CC..SBendtrans-113.167.8177.7-57.9175.2000110.7I343 A359 H362 W366 M367 A496 L529 M531I343-L364 HydrophobicContact CD1-CD2 3.66Å; I343-L364 HydrophobicContact CG1-CD2 4Å; A359-L364 HydrophobicContact CB-CD1 3.93Å; H362-L364 PolarHBondContact O-N 3.33Å; L364-W366 HydrophobicContact CD2-CZ2 3.79Å; L364-W366 PolarHBondContact O-N 2.94Å; L364-M367 HydrophobicContact CB-CG 3.67Å; L364-M367 HydrophobicContact CD1-CG 4.31Å; L364-M367 WeakPolarHBondContact O-CB 3.34Å; L364-M367 PolarHBondContact O-N 2.89Å; L364-A496 HydrophobicContact CD1-CB 3.51Å; L364-L529 HydrophobicContact CB-CD2 4.16Å; L364-L529 HydrophobicContact CD1-CD2 4.2Å; L364-M531 HydrophobicContact CD1-CB 4.2Å; L364-M531 HydrophobicContact CD1-SD 4.3Å
365P94.5Very high81.1Confident3 Ų328.4 Ų28.42%0.01914%0.144CC..THydrogen-bonded Turntrans-69.2-4.8-167.730.8-39.2000114.9P337 S363 I474 S475 K476P337-P365 HydrophobicContact CB-CG 4.37Å; S363-P365 WeakPolarHBondContact O-CD 3.46Å; P365-I474 WeakPolarHBondContact CA-O 3.45Å; P365-I474 VanDerWaalsContact CB-C 3.48Å; P365-I474 WeakPolarHBondContact CB-O 3.49Å; P365-S475 CarbonylContact O-C 3.59Å; P365-S475 WeakPolarHBondContact O-CA 3.04Å; P365-K476 CarbonylContact C-O 3.51Å; P365-K476 HydrophobicContact CB-CB 4.12Å; P365-K476 HydrophobicContact CB-CG 4.34Å; P365-K476 HydrophobicContact CG-CB 4.01Å; P365-K476 HydrophobicContact CG-CD 4.48Å; P365-K476 HydrophobicContact CG-CG 4.34Å; P365-K476 PolarHBondContact O-N 2.83Å
366W96.8Very high81.7Confident1 Ų135.6 Ų35.60%0.00418%0.18CC..THydrogen-bonded Turntrans-91-15.6174.143.978.4000113.8I343 L364 V368 T387 L388 K476 I478 W583I343-W366 HydrophobicContact CD1-CH2 3.53Å; I343-W366 HydrophobicContact CD1-CZ2 3.66Å; L364-W366 HydrophobicContact CD2-CZ2 3.79Å; L364-W366 PolarHBondContact O-N 2.94Å; W366-V368 PolarHBondContact O-N 3.38Å; W366-T387 CarbonylContact O-C 3.5Å; W366-T387 VanDerWaalsContact O-CA 3.23Å; W366-T387 WeakPolarHBondContact O-CA 3.26Å; W366-L388 PolarHBondContact O-N 3.03Å; W366-K476 WeakPolarHBondContact CA-O 3.19Å; W366-K476 VanDerWaalsContact CB-O 3.28Å; W366-K476 WeakPolarHBondContact CB-O 3.47Å; W366-K476 PolarHBondContact N-O 3.37Å; W366-I478 HydrophobicContact CB-CB 3.85Å; W366-I478 HydrophobicContact CD2-CB 4.17Å; W366-I478 HydrophobicContact CD2-CD1 3.72Å; W366-I478 HydrophobicContact CD2-CG1 4.44Å; W366-I478 HydrophobicContact CE3-CD1 4.02Å; W366-I478 HydrophobicContact CG-CB 3.81Å; W366-I478 HydrophobicContact CG-CD1 4.16Å; W366-I478 HydrophobicContact CG-CG1 4.39Å; W366-I478 HydrophobicContact CH2-CD1 4.26Å; W366-I478 HydrophobicContact CZ2-CD1 3.99Å; W366-I478 HydrophobicContact CZ3-CD1 4.28Å; W366-W583 HydrophobicContact CH2-CB 3.79Å; W366-W583 AromaticContact CH2-CD1 3.75Å; W366-W583 AromaticContact CH2-CG 3.82Å; W366-W583 HydrophobicContact CH2-CG 3.82Å; W366-W583 HydrophobicContact CZ2-CB 4.1Å; W366-W583 HydrophobicContact CZ2-CG 4.2Å; W366-W583 HydrophobicContact CZ3-CB 4.46Å
367M95.8Very high81.8Confident5 Ų538.7 Ų38.73%0.02520%0.196CC..EExtended strand (participates in β ladder)trans-67131.8-177.4-70.3-61.3-61.700111.1L364 A496 W498 L529 P574L364-M367 HydrophobicContact CB-CG 3.67Å; L364-M367 HydrophobicContact CD1-CG 4.31Å; L364-M367 WeakPolarHBondContact O-CB 3.34Å; L364-M367 PolarHBondContact O-N 2.89Å; M367-A496 HydrophobicContact CE-CB 4.15Å; M367-A496 VanDerWaalsContact CE-O 3.29Å; M367-A496 WeakPolarHBondContact CE-O 3.36Å; M367-A496 HydrophobicContact SD-CB 4.12Å; M367-W498 HydrophobicContact CB-CH2 3.88Å; M367-W498 HydrophobicContact CE-CH2 4.38Å; M367-W498 HydrophobicContact CE-CZ3 3.94Å; M367-L529 HydrophobicContact CB-CD1 4.39Å; M367-L529 HydrophobicContact CB-CD2 4.05Å; M367-L529 HydrophobicContact CE-CD1 4Å; M367-L529 HydrophobicContact CG-CD1 4.23Å; M367-L529 HydrophobicContact CG-CD2 4.07Å; M367-P574 HydrophobicContact CE-CG 4.45Å; M367-P574 WeakPolarHBondContact SD-CD 3.38Å; M367-P574 HydrophobicContact SD-CG 3.51Å; M367-P574 VanDerWaalsContact SD-CG 3.51Å
368V95.6Very high81.4Confident0 Ų042.3 Ų42.30%022%0.222CC..EExtended strand (participates in β ladder)trans-129.6148.3173.7-50.10000111.3W366 G385 G386 L388 V400 V423 A424 I425 W498W366-V368 PolarHBondContact O-N 3.38Å; V368-G385 CarbonylContact O-C 3.54Å; V368-G386 PolarHBondContact N-O 2.76Å; V368-G386 PolarHBondContact O-N 3.41Å; V368-L388 HydrophobicContact CG1-CD1 4.42Å; V368-L388 HydrophobicContact CG1-CD2 4.08Å; V368-L388 HydrophobicContact CG1-CG 3.67Å; V368-V400 HydrophobicContact CG2-CG1 3.71Å; V368-V400 HydrophobicContact CG2-CG2 4.25Å; V368-V423 HydrophobicContact CB-CG1 3.54Å; V368-V423 HydrophobicContact CG1-CG1 4.14Å; V368-V423 HydrophobicContact CG2-CG1 3.57Å; V368-A424 WeakPolarHBondContact CA-O 3.24Å; V368-A424 WeakPolarHBondContact CB-O 3.3Å; V368-I425 HydrophobicContact CB-CG2 4.49Å; V368-I425 HydrophobicContact CG1-CB 4.45Å; V368-I425 HydrophobicContact CG1-CG2 3.78Å; V368-W498 VanDerWaalsContact O-CZ3 3.31Å; V368-W498 WeakPolarHBondContact O-CZ3 3.28Å
369L92.8Very high80.3Confident8 Ų846 Ų464%0.04224%0.237CC..EExtended strand (participates in β ladder)trans-100.1113.4172.9-178.670.9000108.8I371 L383 V423 A424 Q430 W498L369-I371 HydrophobicContact CD2-CD1 3.91Å; L369-I371 HydrophobicContact CD2-CG1 3.9Å; L369-I371 HydrophobicContact CG-CD1 4.27Å; L369-I371 HydrophobicContact CG-CG1 3.83Å; L369-L383 HydrophobicContact CD2-CD2 4.41Å; L369-V423 CarbonylContact O-C 3.53Å; L369-V423 WeakPolarHBondContact O-CA 3.18Å; L369-A424 HydrophobicContact CB-CB 4.31Å; L369-A424 PolarHBondContact N-O 2.66Å; L369-A424 PolarHBondContact O-N 2.67Å; L369-Q430 VanDerWaalsContact CD1-NE2 3.33Å; L369-Q430 HydrophobicContact CD2-CB 4.44Å; L369-Q430 HydrophobicContact CD2-CG 3.86Å; L369-W498 HydrophobicContact CB-CE3 4.37Å; L369-W498 HydrophobicContact CB-CH2 4.2Å; L369-W498 HydrophobicContact CB-CZ3 4.09Å; L369-W498 HydrophobicContact CD1-CD2 4.33Å; L369-W498 HydrophobicContact CD1-CE3 3.95Å; L369-W498 HydrophobicContact CD1-CZ3 4.41Å
370F93.3Very high79.4Confident0 Ų049.7 Ų49.70%025%0.253CS..EExtended strand (participates in β ladder)trans-79.4130.8168176.3-97.7000109.8A372 L383 C384 C406 V407 C421 V423 V442 I463F370-A372 HydrophobicContact CE1-CB 3.7Å; F370-A372 HydrophobicContact CZ-CB 3.86Å; F370-L383 WeakPolarHBondContact O-CA 3.45Å; F370-C384 HydrophobicContact CB-CB 4.17Å; F370-C384 HydrophobicContact CD1-CB 4.23Å; F370-C384 PolarHBondContact N-O 3.46Å; F370-C384 PolarHBondContact O-N 2.83Å; F370-C406 HydrophobicContact CD1-CB 4.27Å; F370-C406 VanDerWaalsContact CE1-O 3.28Å; F370-C406 WeakPolarHBondContact CE1-O 3.49Å; F370-V407 HydrophobicContact CE2-CG1 4.38Å; F370-V407 HydrophobicContact CZ-CG1 4.04Å; F370-C421 HydrophobicContact CE2-CB 3.93Å; F370-C421 HydrophobicContact CZ-CB 4.06Å; F370-V423 HydrophobicContact CD2-CG2 4.05Å; F370-V442 HydrophobicContact CE2-CG2 4.29Å; F370-I463 HydrophobicContact CD2-CD1 3.39Å; F370-I463 HydrophobicContact CE2-CD1 3.58Å; F370-I463 HydrophobicContact CG-CD1 4.23Å
371I90.7Very high78.9Confident16 Ų1650.8 Ų50.88%0.08226%0.258CS..EExtended strand (participates in β ladder)trans-131.1113.3-174.4-53.9166.5000107.5L369 L383 C421 Q422 A424 R439L369-I371 HydrophobicContact CD2-CD1 3.91Å; L369-I371 HydrophobicContact CD2-CG1 3.9Å; L369-I371 HydrophobicContact CG-CD1 4.27Å; L369-I371 HydrophobicContact CG-CG1 3.83Å; I371-L383 HydrophobicContact CB-CD2 4.24Å; I371-L383 HydrophobicContact CG1-CD2 3.84Å; I371-L383 HydrophobicContact CG2-CD2 3.99Å; I371-C421 CarbonylContact O-C 3.58Å; I371-C421 WeakPolarHBondContact O-CA 3.41Å; I371-Q422 PolarHBondContact N-O 2.98Å; I371-Q422 PolarHBondContact O-N 3.02Å; I371-A424 HydrophobicContact CD1-CB 4.2Å; I371-R439 VanDerWaalsContact CD1-CZ 3.46Å
372A87.9Confident78.6Confident0 Ų047.1 Ų47.10%024%0.244CC..EExtended strand (participates in β ladder)trans-119133.4170.500000109.8F370 H381 A382 W416 D420F370-A372 HydrophobicContact CE1-CB 3.7Å; F370-A372 HydrophobicContact CZ-CB 3.86Å; A372-H381 CarbonylContact O-C 3.45Å; A372-H381 WeakPolarHBondContact O-CA 3.36Å; A372-H381 WeakPolarHBondContact O-CB 3.05Å; A372-A382 HydrophobicContact CB-CB 4.42Å; A372-A382 PolarHBondContact N-O 2.03Å; A372-A382 PolarHBondContact O-N 3.09Å; A372-W416 HydrophobicContact CB-CD2 3.6Å; A372-W416 HydrophobicContact CB-CE3 4Å; A372-W416 HydrophobicContact CB-CG 3.81Å; A372-W416 HydrophobicContact CB-CZ2 4.27Å; A372-W416 HydrophobicContact CB-CZ3 4.47Å; A372-D420 WeakPolarHBondContact CA-O 3.24Å
373A80.7Confident78.5Confident38 Ų3849.1 Ų49.131%0.31426%0.255SS..EExtended strand (participates in β ladder)trans-155.2136.6177.200000111.4H381 D420A373-H381 HydrophobicContact CB-CB 3.87Å; A373-D420 PolarHBondContact N-O 3.48Å
374K71.6Confident78.5Confident82 Ų8249.6 Ų49.636%0.35726%0.258SS..EExtended strand (participates in β ladder)trans-79.8127.1172.7-61.1-139.9170.7-1620110.1N376 N377 K380 W416K374-N376 PolarHBondContact O-N 2.92Å; K374-N377 CarbonylContact O-C 3.58Å; K374-N377 PolarHBondContact O-N 3.17Å; K374-K380 PolarHBondContact N-O 3Å; K374-W416 HydrophobicContact CG-CE3 4.32Å; K374-W416 HydrophobicContact CG-CZ3 3.64Å
375E62.6Low78.5Confident178 Ų17849.3 Ų49.383%0.83226%0.257SS*.THydrogen-bonded Turntrans-48.4-46.6174.1-63.8-175.3144.500111.9N377E375-N377 VanDerWaalsContact C-N 3.25Å; E375-N377 PolarHBondContact O-N 3.31Å
376N61Low78.5Confident162 Ų16249.2 Ų49.287%0.86626%0.256SS*.THydrogen-bonded Turntrans-75.7-6.3-178-63.8-16.4000114.3K374K374-N376 PolarHBondContact O-N 2.92Å
377N57.8Low78.6Confident65 Ų6549.1 Ų49.135%0.34826%0.255SS..EExtended strand (participates in β ladder)trans-155.483177.7-167.5-19.5000112.1K374 E375 M379 K380K374-N377 CarbonylContact O-C 3.58Å; K374-N377 PolarHBondContact O-N 3.17Å; E375-N377 VanDerWaalsContact C-N 3.25Å; E375-N377 PolarHBondContact O-N 3.31Å; N377-M379 PolarHBondContact O-N 2.86Å; N377-M379 WeakPolarHBondContact OD1-CB 2.94Å; N377-M379 PolarHBondContact OD1-N 2.97Å; N377-M379 VanDerWaalsContact OD1-N 3.15Å; N377-K380 PolarHBondContact O-N 2.91Å
378P54.7Low78.7Confident95 Ų9549 Ų4962%0.61725%0.254SS*.EExtended strand (participates in β ladder)trans-64.8-9.4178.125-34.5000114.5K380 H381P378-K380 VanDerWaalsContact C-N 3.3Å; P378-H381 PolarHBondContact O-ND1 2.65Å
379M47.2Very low78.8Confident128 Ų12849 Ų4963%0.63125%0.254SS*.EExtended strand (participates in β ladder)trans-76.2-18.2169.2-62.2-174.270.800112.7N377N377-M379 PolarHBondContact O-N 2.86Å; N377-M379 WeakPolarHBondContact OD1-CB 2.94Å; N377-M379 PolarHBondContact OD1-N 2.97Å; N377-M379 VanDerWaalsContact OD1-N 3.15Å
380K57.1Low78.8Confident80 Ų8050.2 Ų50.235%0.34827%0.266SS..EExtended strand (participates in β ladder)trans-96.186.3166.7-65.6-163-178.2-162.20108.5K374 N377 P378 I409 S411 W416K374-K380 PolarHBondContact N-O 3Å; N377-K380 PolarHBondContact O-N 2.91Å; P378-K380 VanDerWaalsContact C-N 3.3Å; K380-I409 HydrophobicContact CD-CG2 4.49Å; K380-S411 PolarHBondContact NZ-OG 2.96Å; K380-W416 HydrophobicContact CB-CH2 4.27Å; K380-W416 WeakPolarHBondContact O-CH2 3.34Å
381H67.9Low78.8Confident101 Ų10152.7 Ų52.747%0.46828%0.279SS..EExtended strand (participates in β ladder)trans-124.9155.5166.461.4-95.4000111A372 A373 P378A372-H381 CarbonylContact O-C 3.45Å; A372-H381 WeakPolarHBondContact O-CA 3.36Å; A372-H381 WeakPolarHBondContact O-CB 3.05Å; A373-H381 HydrophobicContact CB-CB 3.87Å; P378-H381 PolarHBondContact O-ND1 2.65Å
382A73.7Confident78.6Confident11 Ų1157.6 Ų57.69%0.09130%0.302CS..EExtended strand (participates in β ladder)trans-123.1131.3167.700000108.6A372 W416A372-A382 HydrophobicContact CB-CB 4.42Å; A372-A382 PolarHBondContact N-O 2.03Å; A372-A382 PolarHBondContact O-N 3.09Å; A382-W416 HydrophobicContact CB-CZ2 4.11Å
383L85Confident78.5Confident53 Ų5364 Ų6428%0.27734%0.343SS..EExtended strand (participates in β ladder)trans-118.1123.5170.4-66.7176.7000107.4L369 F370 I371L369-L383 HydrophobicContact CD2-CD2 4.41Å; F370-L383 WeakPolarHBondContact O-CA 3.45Å; I371-L383 HydrophobicContact CB-CD2 4.24Å; I371-L383 HydrophobicContact CG1-CD2 3.84Å; I371-L383 HydrophobicContact CG2-CD2 3.99Å
384C90Very high78.8Confident10 Ų1063.2 Ų63.27%0.06834%0.338CS..EExtended strand (participates in β ladder)trans-139.4154.1-177-87.40000111.5F370 C406 T571F370-C384 HydrophobicContact CB-CB 4.17Å; F370-C384 HydrophobicContact CD1-CB 4.23Å; F370-C384 PolarHBondContact N-O 3.46Å; F370-C384 PolarHBondContact O-N 2.83Å; C384-C406 HydrophobicContact CB-CB 3.63Å; C384-C406 WeakPolarHBondContact CB-SG 3.35Å; C384-C406 VanDerWaalsContact SG-CA 3.59Å; C384-C406 WeakPolarHBondContact SG-CB 3.3Å; C384-C406 CovalentContact SG-SG 2.03Å; C384-C406 PolarHBondContact SG-SG 2.73Å; C384-T571 CarbonylContact C-O 3.53Å; C384-T571 WeakPolarHBondContact CA-O 3.09Å; C384-T571 WeakPolarHBondContact CB-O 3.45Å; C384-T571 PolarHBondContact SG-O 3.34Å; C384-T571 VanDerWaalsContact SG-O 3.38Å
385G91.7Very high79.6Confident0 Ų061.9 Ų61.90%034%0.335CS..EExtended strand (participates in β ladder)trans-73.3168.8164.600000112.7V368 T402 T571 G572V368-G385 CarbonylContact O-C 3.54Å; G385-T402 PolarHBondContact O-OG1 2.8Å; G385-T571 PolarHBondContact N-O 3.2Å; G385-G572 VanDerWaalsContact C-C 3.42Å; G385-G572 CarbonylContact C-O 3.54Å; G385-G572 CarbonylContact O-C 3.31Å; G385-G572 WeakPolarHBondContact O-CA 3.35Å
386G95.5Very high81.1Confident0 Ų057 Ų570%031%0.313CS..EExtended strand (participates in β ladder)trans-173.4-180170.200000110.1V368 L401 G572V368-G386 PolarHBondContact N-O 2.76Å; V368-G386 PolarHBondContact O-N 3.41Å; G386-L401 CarbonylContact C-O 3.56Å; G386-L401 WeakPolarHBondContact CA-O 3.47Å; G386-G572 WeakPolarHBondContact CA-O 3.07Å
387T98.1Very high82.7Confident0 Ų049.7 Ų49.70%027%0.274CS..EExtended strand (participates in β ladder)trans-132.7144.1175.353.80000113.2W366 V400 L401 I478 P574 Q585W366-T387 CarbonylContact O-C 3.5Å; W366-T387 VanDerWaalsContact O-CA 3.23Å; W366-T387 WeakPolarHBondContact O-CA 3.26Å; T387-V400 CarbonylContact O-C 3.55Å; T387-V400 VanDerWaalsContact O-CA 3.23Å; T387-V400 WeakPolarHBondContact O-CA 3.27Å; T387-L401 PolarHBondContact N-O 2.94Å; T387-L401 PolarHBondContact O-N 3.27Å; T387-I478 HydrophobicContact CG2-CG2 4.15Å; T387-P574 HydrophobicContact CG2-CB 3.67Å; T387-P574 HydrophobicContact CG2-CG 3.6Å; T387-Q585 PolarHBondContact OG1-OE1 2.82Å
388L97.7Very high84.6Confident1 Ų147 Ų471%0.00526%0.259CS..EExtended strand (participates in β ladder)trans-66.9126.6159.7-68.6173.7000108.8W366 V368 T397 V400 I425 L465 A469 P477 I478W366-L388 PolarHBondContact O-N 3.03Å; V368-L388 HydrophobicContact CG1-CD1 4.42Å; V368-L388 HydrophobicContact CG1-CD2 4.08Å; V368-L388 HydrophobicContact CG1-CG 3.67Å; L388-T397 HydrophobicContact CB-CG2 4.15Å; L388-T397 HydrophobicContact CD2-CG2 3.84Å; L388-T397 HydrophobicContact CG-CG2 4.49Å; L388-V400 HydrophobicContact CD2-CG2 3.92Å; L388-I425 HydrophobicContact CD1-CG2 4.46Å; L388-I425 HydrophobicContact CD2-CG2 4.19Å; L388-L465 HydrophobicContact CD2-CD1 4.45Å; L388-A469 HydrophobicContact CD2-CB 4.11Å; L388-P477 CarbonylContact O-C 3.55Å; L388-P477 VanDerWaalsContact O-CA 3.25Å; L388-P477 WeakPolarHBondContact O-CA 3.49Å; L388-I478 PolarHBondContact O-N 3.19Å
389I97.5Very high86.6Confident0 Ų042.6 Ų42.60%023%0.23CC..EExtended strand (participates in β ladder)trans-121.8149.9174.658.5160.1000110.1L391 T397 T399 L401 I478 L480 I613I389-L391 HydrophobicContact CD1-CG 4.44Å; I389-T397 VanDerWaalsContact O-CB 3.31Å; I389-T397 WeakPolarHBondContact O-CB 3.29Å; I389-T397 WeakPolarHBondContact O-CG2 3.38Å; I389-T397 PolarHBondContact O-OG1 3.32Å; I389-T399 HydrophobicContact CD1-CG2 3.74Å; I389-T399 HydrophobicContact CG1-CG2 3.79Å; I389-T399 PolarHBondContact N-O 2.75Å; I389-T399 VanDerWaalsContact N-O 3.11Å; I389-L401 HydrophobicContact CD1-CB 4.16Å; I389-L401 HydrophobicContact CG1-CB 4.39Å; I389-L401 HydrophobicContact CG2-CB 3.94Å; I389-I478 HydrophobicContact CG2-CG2 3.86Å; I389-L480 HydrophobicContact CB-CD1 4.49Å; I389-L480 HydrophobicContact CD1-CD1 4.1Å; I389-L480 HydrophobicContact CG2-CD2 3.95Å; I389-L480 HydrophobicContact CG2-CG 4.32Å; I389-I613 HydrophobicContact CD1-CG2 3.98Å
390A93.6Very high89Confident34 Ų3436.5 Ų36.528%0.28120%0.2SC..  trans-118.7119.6174.400000109.6F471 P477A390-F471 HydrophobicContact CB-CZ 4.2Å; A390-P477 HydrophobicContact CB-CB 3.7Å; A390-P477 HydrophobicContact CB-CG 3.79Å
391L92.4Very high91Very high52 Ų5232.7 Ų32.727%0.27218%0.184SC..SBendtrans-97.5-16.5176.9-65.2172.9000112.7I389 T399 L480 I613 K614 D617I389-L391 HydrophobicContact CD1-CG 4.44Å; L391-T399 HydrophobicContact CD1-CG2 4.36Å; L391-L480 HydrophobicContact CD2-CD1 3.7Å; L391-I613 HydrophobicContact CD1-CG2 4.27Å; L391-I613 HydrophobicContact CD2-CG2 4.14Å; L391-K614 HydrophobicContact CD2-CG 4.28Å; L391-D617 HydrophobicContact CD1-CB 3.43Å; L391-D617 VanDerWaalsContact CD1-CB 3.43Å; L391-D617 VanDerWaalsContact CD1-CG 3.49Å
392E87.3Confident92.3Very high120 Ų12027.9 Ų27.956%0.56116%0.162SC*.SBendtrans-127.1147.2175.7-68.1171.2178.300109K622E392-K622 IonicContact OE1-NZ 2.65Å; E392-K622 PolarHBondContact OE1-NZ 2.98Å; E392-K622 IonicContact OE2-NZ 3.33Å; E392-K622 PolarHBondContact OE2-NZ 2.72Å
393P85Confident93.3Very high135 Ų13527.3 Ų27.388%0.87716%0.157SC*.SBendtrans-63.5138.2172-2032.7000111.6
394G86.9Confident93.7Very high20 Ų2024.8 Ų24.821%0.20614%0.144CC..SBendtrans170.6-175178.500000113F471G394-F471 WeakPolarHBondContact O-CD2 3.49Å; G394-F471 WeakPolarHBondContact O-CE2 3.29Å
395N90Very high93.7Very high55 Ų5525.6 Ų25.629%0.29415%0.149SC..SBendtrans-107.620.2179.4-70.3-18.3000112.8F331 F332 F471F331-N395 WeakPolarHBondContact CA-OD1 3.43Å; F332-N395 HydrophobicContact CD2-CB 4.43Å; F332-N395 PolarHBondContact N-OD1 2.85Å; N395-F471 PolarHBondContact O-N 3.08Å
396Q93Very high93.6Very high76 Ų7625.7 Ų25.736%0.35515%0.15SC..EExtended strand (participates in β ladder)trans-161.5159.6-179.169.1-164.74700111Y468 A469 F471 L626Q396-Y468 HydrophobicContact CG-CD1 3.88Å; Q396-Y468 HydrophobicContact CG-CG 4.04Å; Q396-A469 CarbonylContact C-O 3.45Å; Q396-A469 WeakPolarHBondContact CA-O 3.28Å; Q396-A469 WeakPolarHBondContact CB-O 3.45Å; Q396-F471 WeakPolarHBondContact O-CZ 3.42Å; Q396-L626 HydrophobicContact CB-CD1 4.05Å
397T95.7Very high93.3Very high8 Ų825.7 Ų25.75%0.04915%0.15CC..EExtended strand (participates in β ladder)trans-143.1150.3167.1-168.60000111.4L388 I389 T399 Y468 A469 F471L388-T397 HydrophobicContact CB-CG2 4.15Å; L388-T397 HydrophobicContact CD2-CG2 3.84Å; L388-T397 HydrophobicContact CG-CG2 4.49Å; I389-T397 VanDerWaalsContact O-CB 3.31Å; I389-T397 WeakPolarHBondContact O-CB 3.29Å; I389-T397 WeakPolarHBondContact O-CG2 3.38Å; I389-T397 PolarHBondContact O-OG1 3.32Å; T397-T399 PolarHBondContact OG1-N 2.81Å; T397-T399 VanDerWaalsContact OG1-N 3.14Å; T397-Y468 CarbonylContact O-C 3.58Å; T397-A469 PolarHBondContact N-O 2.98Å; T397-A469 WeakPolarHBondContact O-CB 3.47Å; T397-A469 PolarHBondContact O-N 2.86Å; T397-F471 HydrophobicContact CG2-CE1 3.69Å; T397-F471 HydrophobicContact CG2-CZ 4.07Å
398D96.5Very high92.8Very high7 Ų726.5 Ų26.54%0.03716%0.155CC..EExtended strand (participates in β ladder)trans-112.71216960.8-21.1000112R464 L465 Y468 K622 A623D398-R464 CarbonylContact O-C 3.58Å; D398-R464 WeakPolarHBondContact O-CA 3.23Å; D398-R464 IonicContact OD1-CZ 3.54Å; D398-R464 IonicContact OD1-NH1 3.4Å; D398-R464 PolarHBondContact OD1-NH1 3.48Å; D398-R464 WeakPolarHBondContact OD2-CD 3.17Å; D398-R464 IonicContact OD2-CZ 3.58Å; D398-R464 IonicContact OD2-NE 3.87Å; D398-R464 IonicContact OD2-NH1 2.98Å; D398-R464 PolarHBondContact OD2-NH1 3.3Å; D398-L465 HydrophobicContact CB-CB 4.29Å; D398-L465 PolarHBondContact O-N 3.21Å; D398-Y468 HydrophobicContact CB-CD1 3.58Å; D398-Y468 HydrophobicContact CB-CE1 3.88Å; D398-Y468 HydrophobicContact CB-CG 4.15Å; D398-Y468 WeakPolarHBondContact OD1-CE1 3.46Å; D398-K622 WeakPolarHBondContact OD2-CA 3.13Å; D398-A623 HydrophobicContact CB-CB 3.64Å; D398-A623 WeakPolarHBondContact OD2-CB 3.15Å; D398-A623 PolarHBondContact OD2-N 3.19Å
399T97.6Very high91.7Very high3 Ų326.8 Ų26.82%0.01816%0.156CC..EExtended strand (participates in β ladder)trans-113.5127.4-174.6-51.30000111.7I389 L391 T397 V462 I463 D617I389-T399 HydrophobicContact CD1-CG2 3.74Å; I389-T399 HydrophobicContact CG1-CG2 3.79Å; I389-T399 PolarHBondContact N-O 2.75Å; I389-T399 VanDerWaalsContact N-O 3.11Å; L391-T399 HydrophobicContact CD1-CG2 4.36Å; T397-T399 PolarHBondContact OG1-N 2.81Å; T397-T399 VanDerWaalsContact OG1-N 3.14Å; T399-V462 HydrophobicContact CG2-CG1 3.37Å; T399-I463 WeakPolarHBondContact CA-O 3.42Å; T399-D617 WeakPolarHBondContact CG2-OD1 3.44Å; T399-D617 PolarHBondContact OG1-OD1 3.43Å
400V98Very high90.3Very high0 Ų031 Ų310%018%0.183CC..EExtended strand (participates in β ladder)trans-120.9137.6177.8164.10000110.3V368 T387 L388 V423 I463 L465V368-V400 HydrophobicContact CG2-CG1 3.71Å; V368-V400 HydrophobicContact CG2-CG2 4.25Å; T387-V400 CarbonylContact O-C 3.55Å; T387-V400 VanDerWaalsContact O-CA 3.23Å; T387-V400 WeakPolarHBondContact O-CA 3.27Å; L388-V400 HydrophobicContact CD2-CG2 3.92Å; V400-V423 HydrophobicContact CG2-CG1 4.28Å; V400-I463 HydrophobicContact CB-CB 4.07Å; V400-I463 HydrophobicContact CB-CG2 4.43Å; V400-I463 HydrophobicContact CG1-CB 4.36Å; V400-I463 HydrophobicContact CG1-CD1 4.46Å; V400-I463 PolarHBondContact N-O 3.19Å; V400-I463 PolarHBondContact O-N 3.41Å; V400-L465 HydrophobicContact CG2-CD1 4.13Å; V400-L465 HydrophobicContact CG2-CD2 4.18Å; V400-L465 HydrophobicContact CG2-CG 4.23Å
401L98Very high89.1Confident0 Ų032.7 Ų32.70%019%0.193CC..EExtended strand (participates in β ladder)trans-102.4132.9173.9-165.267.9000110.3G386 T387 I389 I460 V462 L480 L588 V606 I613G386-L401 CarbonylContact C-O 3.56Å; G386-L401 WeakPolarHBondContact CA-O 3.47Å; T387-L401 PolarHBondContact N-O 2.94Å; T387-L401 PolarHBondContact O-N 3.27Å; I389-L401 HydrophobicContact CD1-CB 4.16Å; I389-L401 HydrophobicContact CG1-CB 4.39Å; I389-L401 HydrophobicContact CG2-CB 3.94Å; L401-I460 HydrophobicContact CD1-CD1 4.1Å; L401-I460 HydrophobicContact CD1-CG1 4.03Å; L401-V462 HydrophobicContact CD1-CG2 4.14Å; L401-L480 HydrophobicContact CD2-CD2 4.1Å; L401-L588 HydrophobicContact CD2-CD1 4.16Å; L401-L588 HydrophobicContact CG-CD1 3.85Å; L401-V606 HydrophobicContact CD2-CG1 4.06Å; L401-V606 HydrophobicContact CD2-CG2 4.37Å; L401-I613 HydrophobicContact CD1-CD1 3.91Å; L401-I613 HydrophobicContact CD1-CG1 4.11Å; L401-I613 HydrophobicContact CD2-CD1 4.21Å
402T96Very high88.3Confident0 Ų033.3 Ų33.30%020%0.199CC..EExtended strand (participates in β ladder)trans-154.3-176.3177.4-170.30000110.7G385 A461 I463 G572 L588G385-T402 PolarHBondContact O-OG1 2.8Å; T402-A461 HydrophobicContact CG2-CB 4.31Å; T402-A461 PolarHBondContact N-O 2.91Å; T402-A461 PolarHBondContact O-N 3.36Å; T402-A461 VanDerWaalsContact O-O 3.08Å; T402-I463 HydrophobicContact CG2-CD1 3.45Å; T402-I463 VanDerWaalsContact CG2-CD1 3.45Å; T402-I463 HydrophobicContact CG2-CG1 4.03Å; T402-G572 WeakPolarHBondContact OG1-CA 3.32Å; T402-L588 WeakPolarHBondContact O-CD1 3.35Å
403A93.9Very high87.6Confident0 Ų032.9 Ų32.90%020%0.196CC..  trans-79.3151.1177.300000111.3S405 C406 D459 T571 L588A403-S405 VanDerWaalsContact C-N 3.3Å; A403-S405 WeakPolarHBondContact CB-OG 3.23Å; A403-C406 WeakPolarHBondContact O-CB 3.37Å; A403-C406 PolarHBondContact O-N 3.28Å; A403-D459 WeakPolarHBondContact CB-OD1 2.91Å; A403-T571 HydrophobicContact CB-CG2 3.82Å; A403-L588 HydrophobicContact CB-CD2 3.8Å
404A93.6Very high87.6Confident0 Ų031.9 Ų31.90%018%0.182CC..THydrogen-bonded Turntrans-68.5-33.2172.600000111.9C406 V407 T447 F451 D459 A461A404-C406 PolarHBondContact O-N 2.81Å; A404-V407 VanDerWaalsContact O-CG2 3.29Å; A404-V407 WeakPolarHBondContact O-CG2 3.46Å; A404-V407 PolarHBondContact O-N 2.89Å; A404-V407 VanDerWaalsContact O-N 3.17Å; A404-T447 HydrophobicContact CB-CG2 3.92Å; A404-F451 HydrophobicContact CB-CB 4.34Å; A404-F451 HydrophobicContact CB-CD1 3.34Å; A404-F451 HydrophobicContact CB-CD2 4.03Å; A404-F451 HydrophobicContact CB-CE1 3.47Å; A404-F451 VanDerWaalsContact CB-CE1 3.47Å; A404-F451 HydrophobicContact CB-CE2 4.17Å; A404-F451 HydrophobicContact CB-CG 3.63Å; A404-F451 HydrophobicContact CB-CZ 3.9Å; A404-D459 WeakPolarHBondContact CA-OD1 2.99Å; A404-D459 WeakPolarHBondContact CB-OD1 3.34Å; A404-D459 PolarHBondContact N-OD1 3.21Å; A404-A461 HydrophobicContact CB-CB 4.44Å
405S89.1Confident87.5Confident26 Ų2637.9 Ų37.918%0.18220%0.199CC..G310 helixtrans-56.3-29.217249.30000113.5A403 D459 T571 T591A403-S405 VanDerWaalsContact C-N 3.3Å; A403-S405 WeakPolarHBondContact CB-OG 3.23Å; S405-D459 PolarHBondContact N-OD1 3.16Å; S405-D459 PolarHBondContact OG-OD1 3.06Å; S405-D459 VanDerWaalsContact OG-OD1 3.09Å; S405-D459 PolarHBondContact OG-OD2 2.92Å; S405-T571 VanDerWaalsContact OG-CG2 3.32Å; S405-T571 WeakPolarHBondContact OG-CG2 3.21Å; S405-T591 WeakPolarHBondContact CB-OG1 3.31Å; S405-T591 PolarHBondContact OG-OG1 2.7Å
406C90.2Very high87.5Confident2 Ų235.6 Ų35.61%0.01419%0.186CC..G310 helixtrans-72.4-32.7177.2-66.70000113.8F370 C384 A403 A404 L408 T571F370-C406 HydrophobicContact CD1-CB 4.27Å; F370-C406 VanDerWaalsContact CE1-O 3.28Å; F370-C406 WeakPolarHBondContact CE1-O 3.49Å; C384-C406 HydrophobicContact CB-CB 3.63Å; C384-C406 WeakPolarHBondContact CB-SG 3.35Å; C384-C406 VanDerWaalsContact SG-CA 3.59Å; C384-C406 WeakPolarHBondContact SG-CB 3.3Å; C384-C406 CovalentContact SG-SG 2.03Å; C384-C406 PolarHBondContact SG-SG 2.73Å; A403-C406 WeakPolarHBondContact O-CB 3.37Å; A403-C406 PolarHBondContact O-N 3.28Å; A404-C406 PolarHBondContact O-N 2.81Å; C406-L408 VanDerWaalsContact C-N 3.3Å; C406-T571 PolarHBondContact SG-O 3.14Å
407V90.3Very high87.4Confident0 Ų035 Ų350%019%0.185CC..G310 helixtrans-91.410.4-179-59.20000113.5F370 A404 R415 W416 F445 T447 A461 I463F370-V407 HydrophobicContact CE2-CG1 4.38Å; F370-V407 HydrophobicContact CZ-CG1 4.04Å; A404-V407 VanDerWaalsContact O-CG2 3.29Å; A404-V407 WeakPolarHBondContact O-CG2 3.46Å; A404-V407 PolarHBondContact O-N 2.89Å; A404-V407 VanDerWaalsContact O-N 3.17Å; V407-R415 WeakPolarHBondContact O-CA 3.49Å; V407-W416 VanDerWaalsContact C-CD1 3.45Å; V407-W416 PolarHBondContact O-N 2.84Å; V407-W416 VanDerWaalsContact O-N 3.14Å; V407-F445 HydrophobicContact CB-CD2 3.7Å; V407-F445 HydrophobicContact CB-CE1 4.42Å; V407-F445 HydrophobicContact CB-CE2 3.61Å; V407-F445 HydrophobicContact CB-CG 4.16Å; V407-F445 HydrophobicContact CB-CZ 3.98Å; V407-F445 HydrophobicContact CG1-CB 4.43Å; V407-F445 HydrophobicContact CG1-CD1 4.35Å; V407-F445 HydrophobicContact CG1-CD2 4.05Å; V407-F445 HydrophobicContact CG1-CE2 4.37Å; V407-F445 HydrophobicContact CG1-CG 4.03Å; V407-F445 HydrophobicContact CG2-CD2 3.73Å; V407-F445 HydrophobicContact CG2-CE2 3.81Å; V407-T447 HydrophobicContact CG2-CG2 3.37Å; V407-A461 HydrophobicContact CG1-CB 4.49Å; V407-A461 HydrophobicContact CG2-CB 3.98Å; V407-I463 HydrophobicContact CG1-CD1 4.11Å; V407-I463 HydrophobicContact CG1-CG1 4.27Å
408L85.7Confident87.3Confident18 Ų1836.3 Ų36.39%0.09419%0.194CC..BIsolated β-bridgetrans-107.3149.2168.7-58.2-170000111.7C406 P410 F413 R415 W416 F451C406-L408 VanDerWaalsContact C-N 3.3Å; L408-P410 WeakPolarHBondContact O-CD 3.35Å; L408-F413 HydrophobicContact CD1-CB 4.48Å; L408-R415 HydrophobicContact CD2-CB 4.4Å; L408-R415 HydrophobicContact CD2-CG 3.63Å; L408-W416 VanDerWaalsContact C-NE1 3.28Å; L408-W416 PolarHBondContact O-NE1 2.67Å; L408-F451 HydrophobicContact CD1-CE1 3.74Å; L408-F451 HydrophobicContact CG-CE1 4.47Å
409I75.8Confident87.1Confident7 Ų743.5 Ų43.54%0.03623%0.225CC..  trans-77.5115.9173.5-61.4166.3000108.2K380 S411 T412 F413 L414 W416K380-I409 HydrophobicContact CD-CG2 4.49Å; I409-S411 PolarHBondContact O-N 2.79Å; I409-T412 WeakPolarHBondContact CB-OG1 3.36Å; I409-T412 WeakPolarHBondContact CG2-OG1 3.4Å; I409-T412 PolarHBondContact O-N 3.04Å; I409-F413 PolarHBondContact O-N 2.81Å; I409-L414 WeakPolarHBondContact CB-O 3.42Å; I409-L414 HydrophobicContact CD1-CB 4.37Å; I409-L414 WeakPolarHBondContact CG1-O 3.47Å; I409-L414 PolarHBondContact N-O 3.03Å; I409-W416 HydrophobicContact CB-CZ2 4.23Å; I409-W416 HydrophobicContact CD1-CD2 4.41Å; I409-W416 HydrophobicContact CD1-CE3 4.33Å; I409-W416 HydrophobicContact CG1-CD2 3.53Å; I409-W416 HydrophobicContact CG1-CE3 3.83Å; I409-W416 HydrophobicContact CG1-CG 4.03Å; I409-W416 HydrophobicContact CG1-CH2 4.1Å; I409-W416 HydrophobicContact CG1-CZ2 3.84Å; I409-W416 HydrophobicContact CG1-CZ3 4.12Å; I409-W416 HydrophobicContact CG2-CH2 4.45Å; I409-W416 HydrophobicContact CG2-CZ2 4.32Å
410P67.7Low86.7Confident88 Ų8844.6 Ų44.657%0.57123%0.231SC*.THydrogen-bonded Turntrans-58.4-25.1-170.9-28.435.8000115.5L408L408-P410 WeakPolarHBondContact O-CD 3.35Å
411S67.9Low86.5Confident70 Ų7044.7 Ų44.749%0.4923%0.231SC..THydrogen-bonded Turntrans-83.6-15.3-179.364.30000115.3K380 I409K380-S411 PolarHBondContact NZ-OG 2.96Å; I409-S411 PolarHBondContact O-N 2.79Å
412T75.2Confident86.3Confident65 Ų6548.3 Ų48.340%0.39925%0.248SC..THydrogen-bonded Turntrans-141.9-9.4-167.346.10000114.1I409 L414I409-T412 WeakPolarHBondContact CB-OG1 3.36Å; I409-T412 WeakPolarHBondContact CG2-OG1 3.4Å; I409-T412 PolarHBondContact O-N 3.04Å; T412-L414 PolarHBondContact O-N 3Å
413F73.7Confident86.3Confident111 Ų11148.3 Ų48.349%0.48725%0.248SC..  trans55.54.8-174.7-50.4-68.4000115.9L408 I409 S453L408-F413 HydrophobicContact CD1-CB 4.48Å; I409-F413 PolarHBondContact O-N 2.81Å; F413-S453 VanDerWaalsContact CD1-CB 3.43Å
414L84Confident86.3Confident114 Ų11448.4 Ų48.460%0.59725%0.249SC*.PPolyproline II helixtrans-65.7145165.3-61.8175.7000110.1I409 T412I409-L414 WeakPolarHBondContact CB-O 3.42Å; I409-L414 HydrophobicContact CD1-CB 4.37Å; I409-L414 WeakPolarHBondContact CG1-O 3.47Å; I409-L414 PolarHBondContact N-O 3.03Å; T412-L414 PolarHBondContact O-N 3Å
415R86.4Confident86.3Confident146 Ų14648.4 Ų48.455%0.55125%0.249SC*.BIsolated β-bridgetrans-62.5147.5172.6-71.1176175.1166.1-1.8111V407 L408 F445 T447V407-R415 WeakPolarHBondContact O-CA 3.49Å; L408-R415 HydrophobicContact CD2-CB 4.4Å; L408-R415 HydrophobicContact CD2-CG 3.63Å; R415-F445 HydrophobicContact CB-CE2 4.16Å; R415-F445 HydrophobicContact CB-CZ 4.16Å; R415-F445 HydrophobicContact CG-CE2 4.13Å; R415-T447 PolarHBondContact NH2-OG1 3.45Å
416W88.8Confident86.3Confident7 Ų747.5 Ų47.53%0.02724%0.243CC..PPolyproline II helixtrans-64.1156.2164.3-67101000110.7A372 K374 K380 A382 V407 L408 I409 D420 C421 F445A372-W416 HydrophobicContact CB-CD2 3.6Å; A372-W416 HydrophobicContact CB-CE3 4Å; A372-W416 HydrophobicContact CB-CG 3.81Å; A372-W416 HydrophobicContact CB-CZ2 4.27Å; A372-W416 HydrophobicContact CB-CZ3 4.47Å; K374-W416 HydrophobicContact CG-CE3 4.32Å; K374-W416 HydrophobicContact CG-CZ3 3.64Å; K380-W416 HydrophobicContact CB-CH2 4.27Å; K380-W416 WeakPolarHBondContact O-CH2 3.34Å; A382-W416 HydrophobicContact CB-CZ2 4.11Å; V407-W416 VanDerWaalsContact C-CD1 3.45Å; V407-W416 PolarHBondContact O-N 2.84Å; V407-W416 VanDerWaalsContact O-N 3.14Å; L408-W416 VanDerWaalsContact C-NE1 3.28Å; L408-W416 PolarHBondContact O-NE1 2.67Å; I409-W416 HydrophobicContact CB-CZ2 4.23Å; I409-W416 HydrophobicContact CD1-CD2 4.41Å; I409-W416 HydrophobicContact CD1-CE3 4.33Å; I409-W416 HydrophobicContact CG1-CD2 3.53Å; I409-W416 HydrophobicContact CG1-CE3 3.83Å; I409-W416 HydrophobicContact CG1-CG 4.03Å; I409-W416 HydrophobicContact CG1-CH2 4.1Å; I409-W416 HydrophobicContact CG1-CZ2 3.84Å; I409-W416 HydrophobicContact CG1-CZ3 4.12Å; I409-W416 HydrophobicContact CG2-CH2 4.45Å; I409-W416 HydrophobicContact CG2-CZ2 4.32Å; W416-D420 HydrophobicContact CE3-CB 4.42Å; W416-C421 VanDerWaalsContact CB-SG 3.51Å; W416-F445 HydrophobicContact CB-CZ 4.43Å; W416-F445 VanDerWaalsContact O-CZ 3.29Å; W416-F445 WeakPolarHBondContact O-CZ 3.31Å
417D91.5Very high86.1Confident62 Ų6247.9 Ų47.933%0.33225%0.245SC..PPolyproline II helixtrans-78.4130.3163.9-169.4-42.4000107.5K419 D420 C421D417-K419 HydrophobicContact CB-CG 4.21Å; D417-K419 PolarHBondContact O-N 2.6Å; D417-K419 WeakPolarHBondContact OD1-CD 3.44Å; D417-K419 WeakPolarHBondContact OD1-CG 3.39Å; D417-K419 PolarHBondContact OD1-N 2.97Å; D417-K419 VanDerWaalsContact OD1-N 3.08Å; D417-K419 WeakPolarHBondContact OD2-CD 3.42Å; D417-K419 VanDerWaalsContact OD2-CE 3.25Å; D417-K419 WeakPolarHBondContact OD2-CE 3.38Å; D417-K419 IonicContact OD2-NZ 3.97Å; D417-K419 PolarHBondContact OD2-NZ 2.8Å; D417-D420 HydrophobicContact CB-CB 4.49Å; D417-D420 WeakPolarHBondContact O-CB 3.29Å; D417-D420 PolarHBondContact O-N 2.85Å; D417-C421 PolarHBondContact O-SG 3.43Å; D417-C421 VanDerWaalsContact O-SG 3.32Å
418P93.5Very high85.7Confident37 Ų3749 Ų4924%0.2425%0.251CS..G310 helixtrans-49.9-30.6176.4-30.937.4000114.4D420 C421 V442 F445P418-D420 VanDerWaalsContact C-N 3.28Å; P418-D420 PolarHBondContact O-N 3.09Å; P418-C421 WeakPolarHBondContact O-CB 3.25Å; P418-C421 PolarHBondContact O-N 3.32Å; P418-V442 HydrophobicContact CB-CG1 4.27Å; P418-F445 HydrophobicContact CG-CD1 4.31Å; P418-F445 HydrophobicContact CG-CE1 4.01Å
419K92Very high85.2Confident158 Ų15850.2 Ų50.269%0.68726%0.257SS*.G310 helixtrans-67.6-26.6176.583.5-162.2179.9-143.10113.7D417 C421D417-K419 HydrophobicContact CB-CG 4.21Å; D417-K419 PolarHBondContact O-N 2.6Å; D417-K419 WeakPolarHBondContact OD1-CD 3.44Å; D417-K419 WeakPolarHBondContact OD1-CG 3.39Å; D417-K419 PolarHBondContact OD1-N 2.97Å; D417-K419 VanDerWaalsContact OD1-N 3.08Å; D417-K419 WeakPolarHBondContact OD2-CD 3.42Å; D417-K419 VanDerWaalsContact OD2-CE 3.25Å; D417-K419 WeakPolarHBondContact OD2-CE 3.38Å; D417-K419 IonicContact OD2-NZ 3.97Å; D417-K419 PolarHBondContact OD2-NZ 2.8Å; K419-C421 PolarHBondContact O-N 3.23Å
420D90.5Very high85.2Confident26 Ų2651.7 Ų51.714%0.13926%0.264CS..G310 helixtrans-81.13177.9-62.1-8.1000110.8A372 A373 W416 D417 P418A372-D420 WeakPolarHBondContact CA-O 3.24Å; A373-D420 PolarHBondContact N-O 3.48Å; W416-D420 HydrophobicContact CE3-CB 4.42Å; D417-D420 HydrophobicContact CB-CB 4.49Å; D417-D420 WeakPolarHBondContact O-CB 3.29Å; D417-D420 PolarHBondContact O-N 2.85Å; P418-D420 VanDerWaalsContact C-N 3.28Å; P418-D420 PolarHBondContact O-N 3.09Å
421C93.2Very high85.2Confident2 Ų253.1 Ų53.11%0.01426%0.258CS..EExtended strand (participates in β ladder)trans-123.3138-168.4-57.80000113.4F370 I371 W416 D417 P418 K419 V442F370-C421 HydrophobicContact CE2-CB 3.93Å; F370-C421 HydrophobicContact CZ-CB 4.06Å; I371-C421 CarbonylContact O-C 3.58Å; I371-C421 WeakPolarHBondContact O-CA 3.41Å; W416-C421 VanDerWaalsContact CB-SG 3.51Å; D417-C421 PolarHBondContact O-SG 3.43Å; D417-C421 VanDerWaalsContact O-SG 3.32Å; P418-C421 WeakPolarHBondContact O-CB 3.25Å; P418-C421 PolarHBondContact O-N 3.32Å; K419-C421 PolarHBondContact O-N 3.23Å; C421-V442 HydrophobicContact CB-CB 3.83Å; C421-V442 HydrophobicContact CB-CG1 4.47Å; C421-V442 HydrophobicContact CB-CG2 3.78Å; C421-V442 PolarHBondContact O-N 3.46Å
422Q94.4Very high85.2Confident75 Ų7551.5 Ų51.535%0.3525%0.247SC..EExtended strand (participates in β ladder)trans-136.4156.3176.4-62.7-179.7-45.500110.3I371 R439 I440I371-Q422 PolarHBondContact N-O 2.98Å; I371-Q422 PolarHBondContact O-N 3.02Å; Q422-R439 HydrophobicContact CB-CB 4.37Å; Q422-I440 CarbonylContact C-O 3.59Å; Q422-I440 WeakPolarHBondContact CA-O 3.43Å
423V95.3Very high84.7Confident0 Ų052.7 Ų52.70%026%0.256CS..EExtended strand (participates in β ladder)trans-124.1120.7172176.80000108.9V368 L369 F370 V400 I425 R439 I440 V442 I463 L465V368-V423 HydrophobicContact CB-CG1 3.54Å; V368-V423 HydrophobicContact CG1-CG1 4.14Å; V368-V423 HydrophobicContact CG2-CG1 3.57Å; L369-V423 CarbonylContact O-C 3.53Å; L369-V423 WeakPolarHBondContact O-CA 3.18Å; F370-V423 HydrophobicContact CD2-CG2 4.05Å; V400-V423 HydrophobicContact CG2-CG1 4.28Å; V423-I425 HydrophobicContact CG1-CG2 4.27Å; V423-R439 WeakPolarHBondContact O-CA 3.47Å; V423-I440 PolarHBondContact N-O 3.3Å; V423-I440 PolarHBondContact O-N 3.06Å; V423-V442 HydrophobicContact CG2-CG2 3.99Å; V423-I463 HydrophobicContact CG2-CG2 4.4Å; V423-L465 HydrophobicContact CB-CD2 3.76Å; V423-L465 HydrophobicContact CG1-CD2 4.35Å; V423-L465 HydrophobicContact CG2-CD2 3.74Å
424A93.3Very high84.6Confident2 Ų247.9 Ų47.92%0.01724%0.235CC..EExtended strand (participates in β ladder)trans-90.7126.8172.500000110.7V368 L369 I371 V427 K438 R439V368-A424 WeakPolarHBondContact CA-O 3.24Å; V368-A424 WeakPolarHBondContact CB-O 3.3Å; L369-A424 HydrophobicContact CB-CB 4.31Å; L369-A424 PolarHBondContact N-O 2.66Å; L369-A424 PolarHBondContact O-N 2.67Å; I371-A424 HydrophobicContact CD1-CB 4.2Å; A424-V427 HydrophobicContact CB-CG2 3.8Å; A424-K438 WeakPolarHBondContact CA-O 2.95Å; A424-R439 HydrophobicContact CB-CG 4.06Å
425I93.8Very high84.2Confident0 Ų042.8 Ų42.80%021%0.209CC..EExtended strand (participates in β ladder)trans-108.3154-179.663166.3000111.1V368 L388 V423 V427 K438 I440 A469 I632V368-I425 HydrophobicContact CB-CG2 4.49Å; V368-I425 HydrophobicContact CG1-CB 4.45Å; V368-I425 HydrophobicContact CG1-CG2 3.78Å; L388-I425 HydrophobicContact CD1-CG2 4.46Å; L388-I425 HydrophobicContact CD2-CG2 4.19Å; V423-I425 HydrophobicContact CG1-CG2 4.27Å; I425-V427 PolarHBondContact O-N 2.71Å; I425-V427 VanDerWaalsContact O-N 3.08Å; I425-K438 PolarHBondContact N-O 3.13Å; I425-K438 VanDerWaalsContact N-O 3.13Å; I425-K438 WeakPolarHBondContact O-CB 3.49Å; I425-I440 HydrophobicContact CD1-CD1 3.81Å; I425-I440 HydrophobicContact CG1-CD1 4.36Å; I425-I440 HydrophobicContact CG2-CD1 4.4Å; I425-A469 HydrophobicContact CD1-CB 3.86Å; I425-I632 HydrophobicContact CD1-CD1 3.6Å; I425-I632 HydrophobicContact CD1-CG1 4Å; I425-I632 HydrophobicContact CD1-CG2 4.28Å
426A89Confident84Confident8 Ų841 Ų417%0.06621%0.207CC..SBendtrans50.637.1176.300000114.6K438 I474 I632A426-K438 PolarHBondContact O-NZ 3.32Å; A426-I474 HydrophobicContact CB-CB 4.47Å; A426-I474 HydrophobicContact CB-CD1 3.87Å; A426-I474 HydrophobicContact CB-CG1 3.84Å; A426-I474 WeakPolarHBondContact CB-O 3.29Å; A426-I632 HydrophobicContact CB-CG2 3.71Å
427V86.2Confident83.8Confident9 Ų946.4 Ų46.46%0.05523%0.227CC..  trans-100.1122176.31730000108.7A424 I425 N429 K438 W498A424-V427 HydrophobicContact CB-CG2 3.8Å; I425-V427 PolarHBondContact O-N 2.71Å; I425-V427 VanDerWaalsContact O-N 3.08Å; V427-N429 VanDerWaalsContact CG1-O 3.31Å; V427-N429 WeakPolarHBondContact CG1-O 3.26Å; V427-K438 HydrophobicContact CG2-CB 4.2Å; V427-K438 HydrophobicContact CG2-CD 4.16Å; V427-W498 WeakPolarHBondContact O-CZ2 3.38Å
428Q81.4Confident83.6Confident24 Ų2443.6 Ų43.611%0.11221%0.212CC..SBendtrans-83.4-52.7167.3-178.466.626.800110.4A359 K361 W498 D528 L529A359-Q428 PolarHBondContact O-NE2 2.96Å; K361-Q428 HydrophobicContact CG-CB 4.12Å; K361-Q428 HydrophobicContact CG-CG 4.12Å; Q428-W498 PolarHBondContact O-NE1 3.18Å; Q428-D528 CarbonylContact O-C 3.28Å; Q428-L529 PolarHBondContact NE2-O 3.4Å; Q428-L529 PolarHBondContact O-N 2.89Å
429N76.4Confident83.6Confident43 Ų4344.7 Ų44.723%0.2321%0.211CC..BIsolated β-bridgetrans-114.7122.7-177.3-175.9-63.1000110.4V427 R431 S432 A527 D528V427-N429 VanDerWaalsContact CG1-O 3.31Å; V427-N429 WeakPolarHBondContact CG1-O 3.26Å; N429-R431 PolarHBondContact O-N 3.39Å; N429-R431 VanDerWaalsContact O-N 3.08Å; N429-R431 WeakPolarHBondContact OD1-CA 3.44Å; N429-R431 WeakPolarHBondContact OD1-CB 3.22Å; N429-R431 PolarHBondContact OD1-N 2.89Å; N429-S432 VanDerWaalsContact O-CB 3.28Å; N429-S432 WeakPolarHBondContact O-CB 3.37Å; N429-S432 PolarHBondContact O-N 3.41Å; N429-S432 VanDerWaalsContact O-N 3.08Å; N429-S432 PolarHBondContact OD1-N 3.36Å; N429-A527 CarbonylContact C-O 3.14Å; N429-A527 VanDerWaalsContact CA-O 3.24Å; N429-A527 WeakPolarHBondContact CA-O 3.42Å; N429-D528 PolarHBondContact ND2-OD1 3.05Å
430Q75.6Confident83.7Confident39 Ų3937.2 Ų37.218%0.18218%0.179CC..THydrogen-bonded Turntrans-57.6-26.1-176.3-59.6-167.9-13.800114.1L369 S435 W498 A527L369-Q430 VanDerWaalsContact CD1-NE2 3.33Å; L369-Q430 HydrophobicContact CD2-CB 4.44Å; L369-Q430 HydrophobicContact CD2-CG 3.86Å; Q430-S435 WeakPolarHBondContact O-CB 2.83Å; Q430-S435 PolarHBondContact O-OG 2.89Å; Q430-W498 HydrophobicContact CG-CB 4.38Å; Q430-W498 HydrophobicContact CG-CG 4.02Å; Q430-A527 HydrophobicContact CB-CB 4.41Å; Q430-A527 PolarHBondContact N-O 2.98Å
431R68.3Low83.9Confident118 Ų11837 Ų3745%0.44518%0.183SC..THydrogen-bonded Turntrans-101.75.1-175.7-58.9-179.3-179.4-161.7-4.7113N429 T523 A527N429-R431 PolarHBondContact O-N 3.39Å; N429-R431 VanDerWaalsContact O-N 3.08Å; N429-R431 WeakPolarHBondContact OD1-CA 3.44Å; N429-R431 WeakPolarHBondContact OD1-CB 3.22Å; N429-R431 PolarHBondContact OD1-N 2.89Å; R431-T523 PolarHBondContact NH2-O 3.41Å; R431-T523 PolarHBondContact NH2-OG1 2.8Å; R431-A527 HydrophobicContact CG-CB 3.99Å
432S67.8Low84.1Confident36 Ų3637.4 Ų37.425%0.25219%0.185SC..SBendtrans-62.4140.1175.9-173.50000111.1N429 D434 S435N429-S432 VanDerWaalsContact O-CB 3.28Å; N429-S432 WeakPolarHBondContact O-CB 3.37Å; N429-S432 PolarHBondContact O-N 3.41Å; N429-S432 VanDerWaalsContact O-N 3.08Å; N429-S432 PolarHBondContact OD1-N 3.36Å; S432-D434 WeakPolarHBondContact CB-OD1 3.25Å; S432-D434 PolarHBondContact O-N 3.31Å; S432-D434 PolarHBondContact OG-OD1 3.32Å; S432-S435 WeakPolarHBondContact O-CB 3.45Å; S432-S435 PolarHBondContact O-N 3.17Å; S432-S435 PolarHBondContact O-OG 3.16Å
433P64.6Low84.2Confident90 Ų9036.9 Ų36.958%0.58418%0.182SC*.THydrogen-bonded Turntrans-60.4-8.4-179.3-26.135.5000116.7R437P433-R437 PolarHBondContact O-NH2 3.33Å
434D70.8Confident84.3Confident10 Ų1038.3 Ų38.35%0.05319%0.192CC..THydrogen-bonded Turntrans-100.2-9.8173.467.7-27.5000114.5S432 E436 R437 K438 Y635S432-D434 WeakPolarHBondContact CB-OD1 3.25Å; S432-D434 PolarHBondContact O-N 3.31Å; S432-D434 PolarHBondContact OG-OD1 3.32Å; D434-E436 VanDerWaalsContact C-N 3.3Å; D434-E436 PolarHBondContact O-N 3.2Å; D434-R437 PolarHBondContact O-N 2.68Å; D434-K438 PolarHBondContact O-N 3.25Å; D434-K438 VanDerWaalsContact OD2-CE 3.31Å; D434-K438 WeakPolarHBondContact OD2-CE 3.48Å; D434-K438 IonicContact OD2-NZ 3.88Å; D434-K438 PolarHBondContact OD2-NZ 2.84Å; D434-Y635 PolarHBondContact OD2-N 3.42Å
435S76.5Confident84.4Confident7 Ų739.2 Ų39.25%0.04920%0.196CC..THydrogen-bonded Turntrans-59.1-41.2-177670000112Q430 S432 R437 K438 R439Q430-S435 WeakPolarHBondContact O-CB 2.83Å; Q430-S435 PolarHBondContact O-OG 2.89Å; S432-S435 WeakPolarHBondContact O-CB 3.45Å; S432-S435 PolarHBondContact O-N 3.17Å; S432-S435 PolarHBondContact O-OG 3.16Å; S435-R437 VanDerWaalsContact C-N 3.35Å; S435-R437 PolarHBondContact O-N 2.77Å; S435-K438 PolarHBondContact O-N 3.15Å; S435-R439 WeakPolarHBondContact O-CG 3.43Å
436E80.4Confident84.4Confident108 Ų10840.9 Ų40.951%0.50521%0.206SC..G310 helixtrans-59.8-39.8174.6-61.7-51.1119.400113.2D434 K438 R439D434-E436 VanDerWaalsContact C-N 3.3Å; D434-E436 PolarHBondContact O-N 3.2Å; E436-K438 PolarHBondContact O-N 2.93Å; E436-R439 WeakPolarHBondContact O-CB 3.49Å; E436-R439 WeakPolarHBondContact O-CG 3.49Å; E436-R439 PolarHBondContact O-N 2.74Å; E436-R439 IonicContact OE1-CZ 3.75Å; E436-R439 IonicContact OE1-NE 3.68Å; E436-R439 PolarHBondContact OE1-NE 3.37Å; E436-R439 IonicContact OE1-NH2 3.9Å; E436-R439 PolarHBondContact OE1-NH2 3.46Å; E436-R439 IonicContact OE2-CZ 2.86Å; E436-R439 IonicContact OE2-NE 2.7Å; E436-R439 PolarHBondContact OE2-NE 2.84Å; E436-R439 VanDerWaalsContact OE2-NE 3.09Å; E436-R439 IonicContact OE2-NH1 3.24Å; E436-R439 IonicContact OE2-NH2 2.79Å; E436-R439 PolarHBondContact OE2-NH2 3.07Å
437R84.7Confident84.7Confident120 Ų12041.1 Ų41.145%0.45321%0.206SC..G310 helixtrans-70.3-23.2-178.4-56.2-176.2-147.3145.613.8112P433 D434 S435 R439 F627 F631P433-R437 PolarHBondContact O-NH2 3.33Å; D434-R437 PolarHBondContact O-N 2.68Å; S435-R437 VanDerWaalsContact C-N 3.35Å; S435-R437 PolarHBondContact O-N 2.77Å; R437-R439 VanDerWaalsContact C-N 3.31Å; R437-F627 VanDerWaalsContact O-CZ 3.29Å; R437-F627 WeakPolarHBondContact O-CZ 3.41Å; R437-F631 HydrophobicContact CB-CB 4.39Å; R437-F631 WeakPolarHBondContact O-CB 3.35Å
438K88.4Confident85.1Confident3 Ų341.4 Ų41.41%0.01321%0.207CC..G310 helixtrans-89.49.1-179.9-70.2169169.8176.70113.7A424 I425 A426 V427 D434 S435 E436 F631 R633A424-K438 WeakPolarHBondContact CA-O 2.95Å; I425-K438 PolarHBondContact N-O 3.13Å; I425-K438 VanDerWaalsContact N-O 3.13Å; I425-K438 WeakPolarHBondContact O-CB 3.49Å; A426-K438 PolarHBondContact O-NZ 3.32Å; V427-K438 HydrophobicContact CG2-CB 4.2Å; V427-K438 HydrophobicContact CG2-CD 4.16Å; D434-K438 PolarHBondContact O-N 3.25Å; D434-K438 VanDerWaalsContact OD2-CE 3.31Å; D434-K438 WeakPolarHBondContact OD2-CE 3.48Å; D434-K438 IonicContact OD2-NZ 3.88Å; D434-K438 PolarHBondContact OD2-NZ 2.84Å; S435-K438 PolarHBondContact O-N 3.15Å; E436-K438 PolarHBondContact O-N 2.93Å; K438-F631 WeakPolarHBondContact CE-O 3.46Å; K438-F631 WeakPolarHBondContact CG-O 3.21Å; K438-R633 VanDerWaalsContact CE-O 3.29Å; K438-R633 WeakPolarHBondContact CE-O 3.42Å
439R92.5Very high85.6Confident60 Ų6045.3 Ų45.323%0.22623%0.234CC..EExtended strand (participates in β ladder)trans-85.8125.2178.8-63.2-172.6-179.2-157.66.1111.6I371 Q422 V423 A424 S435 E436 R437I371-R439 VanDerWaalsContact CD1-CZ 3.46Å; Q422-R439 HydrophobicContact CB-CB 4.37Å; V423-R439 WeakPolarHBondContact O-CA 3.47Å; A424-R439 HydrophobicContact CB-CG 4.06Å; S435-R439 WeakPolarHBondContact O-CG 3.43Å; E436-R439 WeakPolarHBondContact O-CB 3.49Å; E436-R439 WeakPolarHBondContact O-CG 3.49Å; E436-R439 PolarHBondContact O-N 2.74Å; E436-R439 IonicContact OE1-CZ 3.75Å; E436-R439 IonicContact OE1-NE 3.68Å; E436-R439 PolarHBondContact OE1-NE 3.37Å; E436-R439 IonicContact OE1-NH2 3.9Å; E436-R439 PolarHBondContact OE1-NH2 3.46Å; E436-R439 IonicContact OE2-CZ 2.86Å; E436-R439 IonicContact OE2-NE 2.7Å; E436-R439 PolarHBondContact OE2-NE 2.84Å; E436-R439 VanDerWaalsContact OE2-NE 3.09Å; E436-R439 IonicContact OE2-NH1 3.24Å; E436-R439 IonicContact OE2-NH2 2.79Å; E436-R439 PolarHBondContact OE2-NH2 3.07Å; R437-R439 VanDerWaalsContact C-N 3.31Å
440I95Very high86.3Confident1 Ų150.5 Ų50.51%0.00525%0.251CS..EExtended strand (participates in β ladder)trans-105.5127.2172-47.4-174.8000107.9Q422 V423 I425 L465 H467 A469 F627Q422-I440 CarbonylContact C-O 3.59Å; Q422-I440 WeakPolarHBondContact CA-O 3.43Å; V423-I440 PolarHBondContact N-O 3.3Å; V423-I440 PolarHBondContact O-N 3.06Å; I425-I440 HydrophobicContact CD1-CD1 3.81Å; I425-I440 HydrophobicContact CG1-CD1 4.36Å; I425-I440 HydrophobicContact CG2-CD1 4.4Å; I440-L465 HydrophobicContact CB-CD2 4.45Å; I440-L465 HydrophobicContact CD1-CD1 4.13Å; I440-L465 HydrophobicContact CG2-CB 4Å; I440-L465 HydrophobicContact CG2-CD1 4.47Å; I440-L465 HydrophobicContact CG2-CD2 4.49Å; I440-H467 HydrophobicContact CG2-CB 4.02Å; I440-A469 HydrophobicContact CD1-CB 3.84Å; I440-F627 HydrophobicContact CB-CD2 4.44Å; I440-F627 HydrophobicContact CB-CE2 4.49Å; I440-F627 HydrophobicContact CD1-CB 3.9Å; I440-F627 HydrophobicContact CD1-CD1 4Å; I440-F627 HydrophobicContact CD1-CD2 4.03Å; I440-F627 HydrophobicContact CD1-CG 3.7Å; I440-F627 HydrophobicContact CG1-CB 4.49Å; I440-F627 HydrophobicContact CG1-CD1 4.1Å; I440-F627 HydrophobicContact CG1-CD2 3.67Å; I440-F627 HydrophobicContact CG1-CE1 4.19Å; I440-F627 HydrophobicContact CG1-CE2 3.77Å; I440-F627 HydrophobicContact CG1-CG 3.82Å; I440-F627 HydrophobicContact CG1-CZ 4.01Å; I440-F627 HydrophobicContact CG2-CD2 4.32Å
441G95.3Very high86.9Confident22 Ų2250 Ų5023%0.22725%0.248CC..EExtended strand (participates in β ladder)trans-62.8151.917500000112.2L466G441-L466 WeakPolarHBondContact O-CB 3.26Å; G441-L466 PolarHBondContact O-N 3.14Å
442V96.5Very high87.3Confident10 Ų1048.4 Ų48.46%0.06125%0.251CS..EExtended strand (participates in β ladder)trans-89.3133.8176.5174.40000110.4F370 P418 C421 V423 F445 I463F370-V442 HydrophobicContact CE2-CG2 4.29Å; P418-V442 HydrophobicContact CB-CG1 4.27Å; C421-V442 HydrophobicContact CB-CB 3.83Å; C421-V442 HydrophobicContact CB-CG1 4.47Å; C421-V442 HydrophobicContact CB-CG2 3.78Å; C421-V442 PolarHBondContact O-N 3.46Å; V423-V442 HydrophobicContact CG2-CG2 3.99Å; V442-F445 HydrophobicContact CG1-CD1 4.12Å; V442-I463 HydrophobicContact CB-CG2 4.46Å; V442-I463 HydrophobicContact CG1-CG2 3.84Å; V442-I463 HydrophobicContact CG2-CG2 3.87Å
443K96.5Very high87.4Confident64 Ų6448.9 Ų48.928%0.27826%0.255SS..EExtended strand (participates in β ladder)trans-90.5-44.4178.1-173.9171.6179.4176.90112.1R464 L466 V621 K622K443-R464 HydrophobicContact CB-CG 4.16Å; K443-R464 WeakPolarHBondContact CB-O 3.36Å; K443-R464 HydrophobicContact CD-CG 4.29Å; K443-R464 PolarHBondContact N-O 2.98Å; K443-L466 HydrophobicContact CB-CB 4.5Å; K443-L466 HydrophobicContact CB-CD1 4.27Å; K443-L466 HydrophobicContact CD-CD1 4.44Å; K443-L466 HydrophobicContact CG-CD1 4.3Å; K443-V621 WeakPolarHBondContact CD-O 3.43Å; K443-V621 VanDerWaalsContact CE-O 3.27Å; K443-V621 WeakPolarHBondContact CE-O 3.39Å; K443-V621 PolarHBondContact NZ-O 3.16Å; K443-V621 VanDerWaalsContact NZ-O 3.08Å; K443-K622 PolarHBondContact NZ-O 2.85Å
444S96.6Very high87.6Confident31 Ų3151 Ų5122%0.21726%0.261CS..EExtended strand (participates in β ladder)trans-163.7167177.957.10000110.1R464 M620S444-R464 PolarHBondContact N-O 2.8Å; S444-R464 PolarHBondContact O-N 2.62Å; S444-R464 WeakPolarHBondContact OG-CB 3.29Å; S444-M620 WeakPolarHBondContact OG-CG 3.45Å; S444-M620 PolarHBondContact OG-SD 3.39Å
445F95.7Very high87.5Confident21 Ų2152.5 Ų52.59%0.09227%0.272CS..EExtended strand (participates in β ladder)trans-149.9154.217055.8-102000111.2V407 R415 W416 P418 V442 V462 I463V407-F445 HydrophobicContact CB-CD2 3.7Å; V407-F445 HydrophobicContact CB-CE1 4.42Å; V407-F445 HydrophobicContact CB-CE2 3.61Å; V407-F445 HydrophobicContact CB-CG 4.16Å; V407-F445 HydrophobicContact CB-CZ 3.98Å; V407-F445 HydrophobicContact CG1-CB 4.43Å; V407-F445 HydrophobicContact CG1-CD1 4.35Å; V407-F445 HydrophobicContact CG1-CD2 4.05Å; V407-F445 HydrophobicContact CG1-CE2 4.37Å; V407-F445 HydrophobicContact CG1-CG 4.03Å; V407-F445 HydrophobicContact CG2-CD2 3.73Å; V407-F445 HydrophobicContact CG2-CE2 3.81Å; R415-F445 HydrophobicContact CB-CE2 4.16Å; R415-F445 HydrophobicContact CB-CZ 4.16Å; R415-F445 HydrophobicContact CG-CE2 4.13Å; W416-F445 HydrophobicContact CB-CZ 4.43Å; W416-F445 VanDerWaalsContact O-CZ 3.29Å; W416-F445 WeakPolarHBondContact O-CZ 3.31Å; P418-F445 HydrophobicContact CG-CD1 4.31Å; P418-F445 HydrophobicContact CG-CE1 4.01Å; V442-F445 HydrophobicContact CG1-CD1 4.12Å; F445-V462 CarbonylContact C-O 3.55Å; F445-V462 VanDerWaalsContact CA-O 3.24Å; F445-V462 WeakPolarHBondContact CA-O 3.4Å; F445-I463 HydrophobicContact CB-CB 4.45Å; F445-I463 HydrophobicContact CB-CG1 3.85Å
446V95Very high87.3Confident35 Ų3553 Ų5321%0.21228%0.275CS..EExtended strand (participates in β ladder)trans-128.7123-179.3179.20000109.1A461 V462 W612 A616 M620V446-A461 VanDerWaalsContact O-CA 3.27Å; V446-A461 WeakPolarHBondContact O-CA 3.31Å; V446-V462 PolarHBondContact N-O 3.37Å; V446-V462 PolarHBondContact O-N 2.94Å; V446-W612 HydrophobicContact CG1-CZ2 4.14Å; V446-A616 HydrophobicContact CB-CB 4.11Å; V446-A616 HydrophobicContact CG1-CB 4Å; V446-M620 HydrophobicContact CG2-CE 4.42Å; V446-M620 HydrophobicContact CG2-CG 3.78Å; V446-M620 HydrophobicContact CG2-SD 3.81Å
447T94.4Very high87.7Confident13 Ų1352.1 Ų52.18%0.0827%0.267CS..EExtended strand (participates in β ladder)trans-90.9151.4171.162.70000110.2A404 V407 R415 A461 W612A404-T447 HydrophobicContact CB-CG2 3.92Å; V407-T447 HydrophobicContact CG2-CG2 3.37Å; R415-T447 PolarHBondContact NH2-OG1 3.45Å; T447-A461 HydrophobicContact CG2-CB 4.3Å; T447-W612 VanDerWaalsContact C-CZ2 3.47Å
448H94.4Very high88Confident14 Ų1446.7 Ų46.77%0.06525%0.247CC..  trans-59.9135.2173.9-176.7-91.5000111.2R450 F451 N458 I460 Y609 W612H448-R450 PolarHBondContact CE1-NE 3.45Å; H448-R450 PolarHBondContact ND1-N 2.91Å; H448-R450 VanDerWaalsContact ND1-N 3.18Å; H448-R450 PolarHBondContact O-N 3.47Å; H448-F451 VanDerWaalsContact O-CB 3.27Å; H448-F451 WeakPolarHBondContact O-CB 3.46Å; H448-F451 PolarHBondContact O-N 3.02Å; H448-N458 HydrophobicContact CB-CB 4.15Å; H448-N458 PolarHBondContact CE1-OD1 2.03Å; H448-N458 VanDerWaalsContact CE1-OD1 3.25Å; H448-N458 WeakPolarHBondContact ND1-CB 3.2Å; H448-I460 HydrophobicContact CB-CG2 3.81Å; H448-I460 PolarHBondContact N-O 3.15Å; H448-I460 VanDerWaalsContact N-O 3.13Å; H448-Y609 AromaticContact CD2-CD1 3.86Å; H448-Y609 AromaticContact CD2-CE1 3.86Å; H448-Y609 AromaticContact NE2-CE1 3.82Å; H448-W612 VanDerWaalsContact CA-CZ2 3.48Å; H448-W612 HydrophobicContact CB-CD2 4.35Å; H448-W612 HydrophobicContact CB-CH2 4.39Å; H448-W612 HydrophobicContact CB-CZ2 3.96Å; H448-W612 AromaticContact CD2-CD1 3.66Å; H448-W612 AromaticContact CD2-CD2 3.78Å; H448-W612 AromaticContact CD2-CE2 3.96Å; H448-W612 AromaticContact CD2-CG 3.63Å; H448-W612 AromaticContact CD2-NE1 3.83Å; H448-W612 VanDerWaalsContact N-CZ2 3.26Å
449P91.9Very high88.1Confident107 Ų10746.5 Ų46.570%0.69525%0.246SC*.THydrogen-bonded Turntrans-69.3-17.7-170.726.3-36000114.4
450R91.4Very high88.2Confident151 Ų15143.7 Ų43.757%0.5724%0.236SC*.THydrogen-bonded Turntrans-99.416.4173.1-50.6-177.8-73.1133.76.7113.3H448 N458H448-R450 PolarHBondContact CE1-NE 3.45Å; H448-R450 PolarHBondContact ND1-N 2.91Å; H448-R450 VanDerWaalsContact ND1-N 3.18Å; H448-R450 PolarHBondContact O-N 3.47Å; R450-N458 PolarHBondContact O-ND2 2.85Å
451F88.4Confident88.3Confident28 Ų2843.6 Ų43.612%0.12324%0.235CC..  trans-74.3134.7169.8178.1-120.9000110A404 L408 H448 D459A404-F451 HydrophobicContact CB-CB 4.34Å; A404-F451 HydrophobicContact CB-CD1 3.34Å; A404-F451 HydrophobicContact CB-CD2 4.03Å; A404-F451 HydrophobicContact CB-CE1 3.47Å; A404-F451 VanDerWaalsContact CB-CE1 3.47Å; A404-F451 HydrophobicContact CB-CE2 4.17Å; A404-F451 HydrophobicContact CB-CG 3.63Å; A404-F451 HydrophobicContact CB-CZ 3.9Å; L408-F451 HydrophobicContact CD1-CE1 3.74Å; L408-F451 HydrophobicContact CG-CE1 4.47Å; H448-F451 VanDerWaalsContact O-CB 3.27Å; H448-F451 WeakPolarHBondContact O-CB 3.46Å; H448-F451 PolarHBondContact O-N 3.02Å; F451-D459 HydrophobicContact CD2-CB 4.1Å; F451-D459 HydrophobicContact CE2-CB 3.7Å
452V77.5Confident88.4Confident86 Ų8642.6 Ų42.652%0.52123%0.225SC..  trans-126.3128.4174.5-177.10000107.3D454 S455V452-D454 PolarHBondContact O-N 3.43Å; V452-D454 VanDerWaalsContact O-N 3.07Å; V452-S455 PolarHBondContact O-N 2.89Å; V452-S455 VanDerWaalsContact O-O 3.06Å; V452-S455 PolarHBondContact O-OG 3.33Å
453S69.6Low88.4Confident46 Ų4642.1 Ų42.132%0.32222%0.222SC..THydrogen-bonded Turntrans-52.3-34-171.1500000114.7F413 S455F413-S453 VanDerWaalsContact CD1-CB 3.43Å; S453-S455 VanDerWaalsContact C-N 3.26Å; S453-S455 PolarHBondContact O-N 3.47Å
454D67.8Low88.5Confident135 Ų13539.1 Ų39.172%0.72221%0.209SC*.THydrogen-bonded Turntrans-90.55.8-173.3-56.35.3000111.5V452V452-D454 PolarHBondContact O-N 3.43Å; V452-D454 VanDerWaalsContact O-N 3.07Å
455S68.5Low88.5Confident40 Ų4037.7 Ų37.728%0.2820%0.198SC..  trans-126.9148.8179.181.40000111.6V452 S453 R457V452-S455 PolarHBondContact O-N 2.89Å; V452-S455 VanDerWaalsContact O-O 3.06Å; V452-S455 PolarHBondContact O-OG 3.33Å; S453-S455 VanDerWaalsContact C-N 3.26Å; S453-S455 PolarHBondContact O-N 3.47Å; S455-R457 PolarHBondContact O-N 3.24Å; S455-R457 PolarHBondContact OG-N 3.15Å
456T73.5Confident88.6Confident18 Ų1840.4 Ų40.411%0.1121%0.213CC..  trans-79.1-0168.752.40000112.9S590 V593T456-S590 WeakPolarHBondContact CB-OG 3.34Å; T456-V593 HydrophobicContact CG2-CG2 3.91Å
457R87.8Confident88.6Confident89 Ų8940.9 Ų40.934%0.33621%0.214SC..THydrogen-bonded Turntrans-79.7130.5-174.3-65.1-175.267.8-170.21.9111.4S455 D459 E554 F555S455-R457 PolarHBondContact O-N 3.24Å; S455-R457 PolarHBondContact OG-N 3.15Å; R457-D459 PolarHBondContact O-N 3.31Å; R457-E554 IonicContact CZ-OE1 3.68Å; R457-E554 IonicContact CZ-OE2 3.64Å; R457-E554 IonicContact NE-OE1 3.74Å; R457-E554 IonicContact NE-OE2 2.76Å; R457-E554 PolarHBondContact NE-OE2 3.09Å; R457-E554 VanDerWaalsContact NH2-CD 3.31Å; R457-E554 IonicContact NH2-OE1 2.89Å; R457-E554 PolarHBondContact NH2-OE1 3.45Å; R457-E554 IonicContact NH2-OE2 2.69Å; R457-E554 PolarHBondContact NH2-OE2 3.38Å; R457-E554 VanDerWaalsContact NH2-OE2 3.1Å; R457-F555 HydrophobicContact CG-CE2 4.08Å; R457-F555 HydrophobicContact CG-CZ 3.91Å
458N90.7Very high88.7Confident6 Ų642.4 Ų42.43%0.03222%0.218CC..THydrogen-bonded Turntrans56.530.9-175.3-41.8-83.1000113.6H448 R450 I460 Y609H448-N458 HydrophobicContact CB-CB 4.15Å; H448-N458 PolarHBondContact CE1-OD1 2.03Å; H448-N458 VanDerWaalsContact CE1-OD1 3.25Å; H448-N458 WeakPolarHBondContact ND1-CB 3.2Å; R450-N458 PolarHBondContact O-ND2 2.85Å; N458-I460 VanDerWaalsContact C-N 3.26Å; N458-I460 PolarHBondContact O-N 3.45Å; N458-Y609 WeakPolarHBondContact CA-OH 3.32Å; N458-Y609 HydrophobicContact CB-CE1 4.16Å; N458-Y609 WeakPolarHBondContact OD1-CE1 3.37Å; N458-Y609 PolarHBondContact OD1-OH 2.77Å
459D91.7Very high88.7Confident0 Ų041.7 Ų41.70%022%0.215CC..  trans-74.180.7177.4-170.911.2000110.3A403 A404 S405 F451 R457 S590 T591 T604A403-D459 WeakPolarHBondContact CB-OD1 2.91Å; A404-D459 WeakPolarHBondContact CA-OD1 2.99Å; A404-D459 WeakPolarHBondContact CB-OD1 3.34Å; A404-D459 PolarHBondContact N-OD1 3.21Å; S405-D459 PolarHBondContact N-OD1 3.16Å; S405-D459 PolarHBondContact OG-OD1 3.06Å; S405-D459 VanDerWaalsContact OG-OD1 3.09Å; S405-D459 PolarHBondContact OG-OD2 2.92Å; F451-D459 HydrophobicContact CD2-CB 4.1Å; F451-D459 HydrophobicContact CE2-CB 3.7Å; R457-D459 PolarHBondContact O-N 3.31Å; D459-S590 VanDerWaalsContact CB-OG 3.3Å; D459-S590 WeakPolarHBondContact CB-OG 3.42Å; D459-S590 WeakPolarHBondContact OD2-CA 3.48Å; D459-S590 WeakPolarHBondContact OD2-CB 3.34Å; D459-S590 PolarHBondContact OD2-OG 2.84Å; D459-T591 PolarHBondContact OD2-N 3.4Å; D459-T604 PolarHBondContact O-OG1 3.28Å; D459-T604 VanDerWaalsContact O-OG1 3.09Å
460I95Very high88.8Confident0 Ų037.2 Ų37.20%019%0.186CC..  trans-151.7135.6-176.6-165.1173.4000111.5L401 H448 N458 L588 T604 Y609 W612 I613L401-I460 HydrophobicContact CD1-CD1 4.1Å; L401-I460 HydrophobicContact CD1-CG1 4.03Å; H448-I460 HydrophobicContact CB-CG2 3.81Å; H448-I460 PolarHBondContact N-O 3.15Å; H448-I460 VanDerWaalsContact N-O 3.13Å; N458-I460 VanDerWaalsContact C-N 3.26Å; N458-I460 PolarHBondContact O-N 3.45Å; I460-L588 HydrophobicContact CG1-CD1 4.43Å; I460-T604 HydrophobicContact CB-CG2 4.28Å; I460-Y609 HydrophobicContact CD1-CD2 4.2Å; I460-Y609 HydrophobicContact CD1-CG 4.04Å; I460-Y609 HydrophobicContact CG2-CD1 4.03Å; I460-Y609 HydrophobicContact CG2-CE1 4.34Å; I460-Y609 HydrophobicContact CG2-CG 4.16Å; I460-W612 HydrophobicContact CB-CZ3 4.3Å; I460-W612 HydrophobicContact CD1-CE3 4.5Å; I460-W612 HydrophobicContact CD1-CZ3 4.13Å; I460-W612 HydrophobicContact CG1-CZ3 3.91Å; I460-W612 HydrophobicContact CG2-CE3 4.02Å; I460-W612 HydrophobicContact CG2-CH2 4.15Å; I460-W612 HydrophobicContact CG2-CZ3 3.66Å; I460-I613 HydrophobicContact CD1-CD1 4.07Å; I460-I613 HydrophobicContact CD1-CG1 4.28Å
461A95.9Very high88.8Confident0 Ų030.6 Ų30.60%016%0.161CC..EExtended strand (participates in β ladder)trans-137.1144.6177.100000111.7T402 A404 V407 V446 T447T402-A461 HydrophobicContact CG2-CB 4.31Å; T402-A461 PolarHBondContact N-O 2.91Å; T402-A461 PolarHBondContact O-N 3.36Å; T402-A461 VanDerWaalsContact O-O 3.08Å; A404-A461 HydrophobicContact CB-CB 4.44Å; V407-A461 HydrophobicContact CG1-CB 4.49Å; V407-A461 HydrophobicContact CG2-CB 3.98Å; V446-A461 VanDerWaalsContact O-CA 3.27Å; V446-A461 WeakPolarHBondContact O-CA 3.31Å; T447-A461 HydrophobicContact CG2-CB 4.3Å
462V97.7Very high88.8Confident0 Ų030.8 Ų30.80%017%0.165CC..EExtended strand (participates in β ladder)trans-106.5126.8169.2-171.20000108.2T399 L401 F445 V446 W612 I613 A616 M620T399-V462 HydrophobicContact CG2-CG1 3.37Å; L401-V462 HydrophobicContact CD1-CG2 4.14Å; F445-V462 CarbonylContact C-O 3.55Å; F445-V462 VanDerWaalsContact CA-O 3.24Å; F445-V462 WeakPolarHBondContact CA-O 3.4Å; V446-V462 PolarHBondContact N-O 3.37Å; V446-V462 PolarHBondContact O-N 2.94Å; V462-W612 HydrophobicContact CG2-CH2 3.85Å; V462-W612 HydrophobicContact CG2-CZ3 3.78Å; V462-I613 HydrophobicContact CG2-CB 4.42Å; V462-I613 HydrophobicContact CG2-CG1 4.34Å; V462-I613 HydrophobicContact CG2-CG2 4.11Å; V462-A616 HydrophobicContact CB-CB 4.13Å; V462-A616 HydrophobicContact CG2-CB 3.83Å; V462-M620 HydrophobicContact CB-CE 3.99Å; V462-M620 HydrophobicContact CG1-CE 3.69Å
463I97.6Very high89.2Confident0 Ų030.6 Ų30.60%016%0.158CC..EExtended strand (participates in β ladder)trans-103.5134.3176.4-68.7173.5000108.9F370 T399 V400 T402 V407 V423 V442 F445 L465F370-I463 HydrophobicContact CD2-CD1 3.39Å; F370-I463 HydrophobicContact CE2-CD1 3.58Å; F370-I463 HydrophobicContact CG-CD1 4.23Å; T399-I463 WeakPolarHBondContact CA-O 3.42Å; V400-I463 HydrophobicContact CB-CB 4.07Å; V400-I463 HydrophobicContact CB-CG2 4.43Å; V400-I463 HydrophobicContact CG1-CB 4.36Å; V400-I463 HydrophobicContact CG1-CD1 4.46Å; V400-I463 PolarHBondContact N-O 3.19Å; V400-I463 PolarHBondContact O-N 3.41Å; T402-I463 HydrophobicContact CG2-CD1 3.45Å; T402-I463 VanDerWaalsContact CG2-CD1 3.45Å; T402-I463 HydrophobicContact CG2-CG1 4.03Å; V407-I463 HydrophobicContact CG1-CD1 4.11Å; V407-I463 HydrophobicContact CG1-CG1 4.27Å; V423-I463 HydrophobicContact CG2-CG2 4.4Å; V442-I463 HydrophobicContact CB-CG2 4.46Å; V442-I463 HydrophobicContact CG1-CG2 3.84Å; V442-I463 HydrophobicContact CG2-CG2 3.87Å; F445-I463 HydrophobicContact CB-CB 4.45Å; F445-I463 HydrophobicContact CB-CG1 3.85Å; I463-L465 HydrophobicContact CG2-CD2 4.31Å
464R97.6Very high90.1Very high2 Ų229.1 Ų29.11%0.00815%0.146CC..EExtended strand (participates in β ladder)trans-99.7123.3167.7-178.871.268.2-178.5-3.7109.2D398 K443 S444 D617 M620D398-R464 CarbonylContact O-C 3.58Å; D398-R464 WeakPolarHBondContact O-CA 3.23Å; D398-R464 IonicContact OD1-CZ 3.54Å; D398-R464 IonicContact OD1-NH1 3.4Å; D398-R464 PolarHBondContact OD1-NH1 3.48Å; D398-R464 WeakPolarHBondContact OD2-CD 3.17Å; D398-R464 IonicContact OD2-CZ 3.58Å; D398-R464 IonicContact OD2-NE 3.87Å; D398-R464 IonicContact OD2-NH1 2.98Å; D398-R464 PolarHBondContact OD2-NH1 3.3Å; K443-R464 HydrophobicContact CB-CG 4.16Å; K443-R464 WeakPolarHBondContact CB-O 3.36Å; K443-R464 HydrophobicContact CD-CG 4.29Å; K443-R464 PolarHBondContact N-O 2.98Å; S444-R464 PolarHBondContact N-O 2.8Å; S444-R464 PolarHBondContact O-N 2.62Å; S444-R464 WeakPolarHBondContact OG-CB 3.29Å; R464-D617 IonicContact CZ-OD1 2.68Å; R464-D617 IonicContact CZ-OD2 3.97Å; R464-D617 IonicContact NH1-OD1 2.68Å; R464-D617 IonicContact NH1-OD2 2.64Å; R464-D617 PolarHBondContact NH2-O 2.77Å; R464-D617 IonicContact NH2-OD1 2.9Å; R464-D617 PolarHBondContact NH2-OD1 3.47Å; R464-D617 IonicContact NH2-OD2 2.81Å; R464-D617 PolarHBondContact NH2-OD2 2.96Å; R464-M620 HydrophobicContact CB-CB 4.16Å; R464-M620 HydrophobicContact CB-CE 4.01Å; R464-M620 HydrophobicContact CB-SD 3.62Å; R464-M620 HydrophobicContact CG-CB 4.37Å; R464-M620 PolarHBondContact NH2-O 3.11Å
465L97.5Very high91.3Very high0 Ų022.7 Ų22.70%011%0.112CC..EExtended strand (participates in β ladder)trans-76.3154.7174.6-59.1-179.3000111.3L388 D398 V400 V423 I440 I463 H467 A469L388-L465 HydrophobicContact CD2-CD1 4.45Å; D398-L465 HydrophobicContact CB-CB 4.29Å; D398-L465 PolarHBondContact O-N 3.21Å; V400-L465 HydrophobicContact CG2-CD1 4.13Å; V400-L465 HydrophobicContact CG2-CD2 4.18Å; V400-L465 HydrophobicContact CG2-CG 4.23Å; V423-L465 HydrophobicContact CB-CD2 3.76Å; V423-L465 HydrophobicContact CG1-CD2 4.35Å; V423-L465 HydrophobicContact CG2-CD2 3.74Å; I440-L465 HydrophobicContact CB-CD2 4.45Å; I440-L465 HydrophobicContact CD1-CD1 4.13Å; I440-L465 HydrophobicContact CG2-CB 4Å; I440-L465 HydrophobicContact CG2-CD1 4.47Å; I440-L465 HydrophobicContact CG2-CD2 4.49Å; I463-L465 HydrophobicContact CG2-CD2 4.31Å; L465-H467 VanDerWaalsContact C-N 3.34Å; L465-H467 VanDerWaalsContact CB-O 3.29Å; L465-H467 WeakPolarHBondContact CB-O 3.38Å; L465-A469 HydrophobicContact CD1-CB 4.38Å
466L96.4Very high92.5Very high78 Ų7821.7 Ų21.741%0.40810%0.103SC..EExtended strand (participates in β ladder)trans-72.3-30.9176.1-17163.9000112.4G441 K443G441-L466 WeakPolarHBondContact O-CB 3.26Å; G441-L466 PolarHBondContact O-N 3.14Å; K443-L466 HydrophobicContact CB-CB 4.5Å; K443-L466 HydrophobicContact CB-CD1 4.27Å; K443-L466 HydrophobicContact CD-CD1 4.44Å; K443-L466 HydrophobicContact CG-CD1 4.3Å
467H96Very high93.6Very high46 Ų4620.9 Ų20.921%0.21310%0.098CC..EExtended strand (participates in β ladder)trans-126.3148.7176.2-56.980.8000109.5I440 L465 A469 Q625 F627I440-H467 HydrophobicContact CG2-CB 4.02Å; L465-H467 VanDerWaalsContact C-N 3.34Å; L465-H467 VanDerWaalsContact CB-O 3.29Å; L465-H467 WeakPolarHBondContact CB-O 3.38Å; H467-A469 PolarHBondContact O-N 3.17Å; H467-Q625 CarbonylContact C-O 3.56Å; H467-Q625 VanDerWaalsContact CA-O 3.28Å; H467-Q625 WeakPolarHBondContact CA-O 3.37Å; H467-F627 HydrophobicContact CB-CB 3.93Å; H467-F627 HydrophobicContact CB-CD2 4.23Å
468Y96.4Very high94Very high44 Ų4416.7 Ų16.717%0.1738%0.082CC..EExtended strand (participates in β ladder)trans-65.2127.9168.6-69.2-81.9000109.8Q396 T397 D398 P470 A623 Q625 F627Q396-Y468 HydrophobicContact CG-CD1 3.88Å; Q396-Y468 HydrophobicContact CG-CG 4.04Å; T397-Y468 CarbonylContact O-C 3.58Å; D398-Y468 HydrophobicContact CB-CD1 3.58Å; D398-Y468 HydrophobicContact CB-CE1 3.88Å; D398-Y468 HydrophobicContact CB-CG 4.15Å; D398-Y468 WeakPolarHBondContact OD1-CE1 3.46Å; Y468-P470 VanDerWaalsContact O-CD 3.22Å; Y468-P470 WeakPolarHBondContact O-CD 3.38Å; Y468-A623 HydrophobicContact CD1-CB 4.46Å; Y468-A623 HydrophobicContact CD2-CB 3.73Å; Y468-A623 HydrophobicContact CE1-CB 4.49Å; Y468-A623 HydrophobicContact CE2-CB 3.78Å; Y468-A623 WeakPolarHBondContact CE2-O 3.4Å; Y468-A623 HydrophobicContact CG-CB 4.07Å; Y468-A623 PolarHBondContact OH-O 3.28Å; Y468-Q625 PolarHBondContact N-O 3.02Å; Y468-F627 VanDerWaalsContact O-CB 3.24Å; Y468-F627 WeakPolarHBondContact O-CB 3.33Å; Y468-F627 PolarHBondContact O-N 2.82Å
469A94.9Very high94.4Very high0 Ų017 Ų170%08%0.084CC..EExtended strand (participates in β ladder)trans-74.7113.4164.600000109.1L388 Q396 T397 I425 I440 L465 H467L388-A469 HydrophobicContact CD2-CB 4.11Å; Q396-A469 CarbonylContact C-O 3.45Å; Q396-A469 WeakPolarHBondContact CA-O 3.28Å; Q396-A469 WeakPolarHBondContact CB-O 3.45Å; T397-A469 PolarHBondContact N-O 2.98Å; T397-A469 WeakPolarHBondContact O-CB 3.47Å; T397-A469 PolarHBondContact O-N 2.86Å; I425-A469 HydrophobicContact CD1-CB 3.86Å; I440-A469 HydrophobicContact CD1-CB 3.84Å; L465-A469 HydrophobicContact CD1-CB 4.38Å; H467-A469 PolarHBondContact O-N 3.17Å
470P92.3Very high94.6Very high13 Ų1318.5 Ų18.58%0.0849%0.092CC..EExtended strand (participates in β ladder)trans-65.9149.9171.425-31.5000111.4Y468 S475 L626 I632Y468-P470 VanDerWaalsContact O-CD 3.22Å; Y468-P470 WeakPolarHBondContact O-CD 3.38Å; P470-S475 PolarHBondContact O-OG 3.41Å; P470-L626 HydrophobicContact CB-CD1 3.98Å; P470-L626 HydrophobicContact CB-CD2 4.45Å; P470-L626 HydrophobicContact CB-CG 4.41Å; P470-L626 HydrophobicContact CG-CD1 4.24Å; P470-L626 HydrophobicContact CG-CG 4.33Å; P470-I632 HydrophobicContact CG-CD1 3.58Å
471F91.6Very high94.7Very high12 Ų1218.7 Ų18.75%0.0539%0.093CC..  trans-83.2136.7173.5-58.3-25.5000110.7F332 A390 G394 N395 Q396 T397 S475 P477F332-F471 HydrophobicContact CB-CB 3.92Å; F332-F471 HydrophobicContact CB-CD2 3.88Å; F332-F471 HydrophobicContact CB-CG 4.3Å; F332-F471 HydrophobicContact CD1-CB 4.39Å; F332-F471 HydrophobicContact CD2-CB 3.49Å; F332-F471 VanDerWaalsContact CD2-CB 3.49Å; F332-F471 HydrophobicContact CE2-CB 4.03Å; F332-F471 WeakPolarHBondContact CE2-O 3.33Å; F332-F471 HydrophobicContact CG-CB 3.69Å; A390-F471 HydrophobicContact CB-CZ 4.2Å; G394-F471 WeakPolarHBondContact O-CD2 3.49Å; G394-F471 WeakPolarHBondContact O-CE2 3.29Å; N395-F471 PolarHBondContact O-N 3.08Å; Q396-F471 WeakPolarHBondContact O-CZ 3.42Å; T397-F471 HydrophobicContact CG2-CE1 3.69Å; T397-F471 HydrophobicContact CG2-CZ 4.07Å; F471-S475 CarbonylContact C-O 3.52Å; F471-S475 VanDerWaalsContact CA-O 3.24Å; F471-S475 WeakPolarHBondContact CA-O 3.13Å; F471-P477 HydrophobicContact CD2-CG 4.41Å; F471-P477 HydrophobicContact CE1-CB 4.22Å; F471-P477 HydrophobicContact CE1-CG 3.93Å; F471-P477 HydrophobicContact CE2-CG 3.76Å; F471-P477 HydrophobicContact CZ-CB 4Å; F471-P477 HydrophobicContact CZ-CG 3.49Å; F471-P477 VanDerWaalsContact CZ-CG 3.49Å
472T88.7Confident94.7Very high32 Ų3225 Ų2520%0.19612%0.123CC..  trans-140.9-172.4-17774.90000109.5I474 S475 K476T472-I474 PolarHBondContact O-N 3.41Å; T472-I474 PolarHBondContact OG1-N 3.42Å; T472-I474 VanDerWaalsContact OG1-N 3.14Å; T472-S475 PolarHBondContact N-O 2.88Å; T472-S475 PolarHBondContact OG1-N 2.9Å; T472-S475 VanDerWaalsContact OG1-N 3.09Å; T472-K476 VanDerWaalsContact O-CE 3.24Å; T472-K476 WeakPolarHBondContact O-CE 3.42Å; T472-K476 WeakPolarHBondContact O-CG 3.32Å
473E85.9Confident94.7Very high81 Ų8127.9 Ų27.938%0.37914%0.141SC..SBendtrans-67.3-20172.2-61.1-171.2146.300113.4S338 K340 F341S338-E473 WeakPolarHBondContact CB-O 3.43Å; K340-E473 WeakPolarHBondContact CD-OE2 3.1Å; K340-E473 VanDerWaalsContact CE-OE1 3.32Å; K340-E473 WeakPolarHBondContact CE-OE1 3.27Å; K340-E473 IonicContact NZ-OE1 2.85Å; K340-E473 PolarHBondContact NZ-OE1 3.25Å; K340-E473 IonicContact NZ-OE2 3.47Å; K340-E473 PolarHBondContact NZ-OE2 2.98Å; F341-E473 HydrophobicContact CE2-CB 4.3Å
474I88.6Confident94.4Very high16 Ų1630.2 Ų30.28%0.08217%0.166CC..SBendtrans-121.3-2.6-173.171.7169000114.1F341 H362 P365 A426 T472 I632F341-I474 HydrophobicContact CD2-CG2 3.99Å; F341-I474 HydrophobicContact CE2-CG2 3.52Å; F341-I474 HydrophobicContact CZ-CG2 4.23Å; H362-I474 HydrophobicContact CB-CB 3.86Å; H362-I474 HydrophobicContact CB-CG2 3.6Å; H362-I474 VanDerWaalsContact CG-CG2 3.43Å; P365-I474 WeakPolarHBondContact CA-O 3.45Å; P365-I474 VanDerWaalsContact CB-C 3.48Å; P365-I474 WeakPolarHBondContact CB-O 3.49Å; A426-I474 HydrophobicContact CB-CB 4.47Å; A426-I474 HydrophobicContact CB-CD1 3.87Å; A426-I474 HydrophobicContact CB-CG1 3.84Å; A426-I474 WeakPolarHBondContact CB-O 3.29Å; T472-I474 PolarHBondContact O-N 3.41Å; T472-I474 PolarHBondContact OG1-N 3.42Å; T472-I474 VanDerWaalsContact OG1-N 3.14Å; I474-I632 WeakPolarHBondContact CD1-O 3.31Å; I474-I632 HydrophobicContact CG1-CG2 4.34Å
475S92.6Very high94.3Very high0 Ų032.7 Ų32.70%018%0.178CC..  trans-134.4110.2177.8173.10000108.1P365 P470 F471 T472P365-S475 CarbonylContact O-C 3.59Å; P365-S475 WeakPolarHBondContact O-CA 3.04Å; P470-S475 PolarHBondContact O-OG 3.41Å; F471-S475 CarbonylContact C-O 3.52Å; F471-S475 VanDerWaalsContact CA-O 3.24Å; F471-S475 WeakPolarHBondContact CA-O 3.13Å; T472-S475 PolarHBondContact N-O 2.88Å; T472-S475 PolarHBondContact OG1-N 2.9Å; T472-S475 VanDerWaalsContact OG1-N 3.09Å
476K93.5Very high94.1Very high19 Ų1939.9 Ų39.98%0.08321%0.209CC..  trans-150.3156.7-176.5-67.1-166.5-173.7-170.80110.8F332 V336 P365 W366 T472F332-K476 HydrophobicContact CD1-CD 4.24Å; F332-K476 HydrophobicContact CD1-CG 4.49Å; V336-K476 WeakPolarHBondContact O-CD 3.14Å; V336-K476 PolarHBondContact O-NZ 2.92Å; P365-K476 CarbonylContact C-O 3.51Å; P365-K476 HydrophobicContact CB-CB 4.12Å; P365-K476 HydrophobicContact CB-CG 4.34Å; P365-K476 HydrophobicContact CG-CB 4.01Å; P365-K476 HydrophobicContact CG-CD 4.48Å; P365-K476 HydrophobicContact CG-CG 4.34Å; P365-K476 PolarHBondContact O-N 2.83Å; W366-K476 WeakPolarHBondContact CA-O 3.19Å; W366-K476 VanDerWaalsContact CB-O 3.28Å; W366-K476 WeakPolarHBondContact CB-O 3.47Å; W366-K476 PolarHBondContact N-O 3.37Å; T472-K476 VanDerWaalsContact O-CE 3.24Å; T472-K476 WeakPolarHBondContact O-CE 3.42Å; T472-K476 WeakPolarHBondContact O-CG 3.32Å
477P96.7Very high93.9Very high1 Ų137.4 Ų37.41%0.00620%0.196CC..PPolyproline II helixtrans-80.1149.2177.933.2-31.2000111.7C334 G335 L388 A390 F471C334-P477 CarbonylContact C-O 3.57Å; C334-P477 WeakPolarHBondContact CA-O 3.32Å; C334-P477 HydrophobicContact CB-CG 4.11Å; G335-P477 PolarHBondContact N-O 2.84Å; L388-P477 CarbonylContact O-C 3.55Å; L388-P477 VanDerWaalsContact O-CA 3.25Å; L388-P477 WeakPolarHBondContact O-CA 3.49Å; A390-P477 HydrophobicContact CB-CB 3.7Å; A390-P477 HydrophobicContact CB-CG 3.79Å; F471-P477 HydrophobicContact CD2-CG 4.41Å; F471-P477 HydrophobicContact CE1-CB 4.22Å; F471-P477 HydrophobicContact CE1-CG 3.93Å; F471-P477 HydrophobicContact CE2-CG 3.76Å; F471-P477 HydrophobicContact CZ-CB 4Å; F471-P477 HydrophobicContact CZ-CG 3.49Å; F471-P477 VanDerWaalsContact CZ-CG 3.49Å
478I97.6Very high93.8Very high1 Ų139.5 Ų39.51%0.00521%0.213CC..BIsolated β-bridgetrans-79.4151163.6-167.761.5000109.5W366 T387 L388 I389 V576 W583 Q585W366-I478 HydrophobicContact CB-CB 3.85Å; W366-I478 HydrophobicContact CD2-CB 4.17Å; W366-I478 HydrophobicContact CD2-CD1 3.72Å; W366-I478 HydrophobicContact CD2-CG1 4.44Å; W366-I478 HydrophobicContact CE3-CD1 4.02Å; W366-I478 HydrophobicContact CG-CB 3.81Å; W366-I478 HydrophobicContact CG-CD1 4.16Å; W366-I478 HydrophobicContact CG-CG1 4.39Å; W366-I478 HydrophobicContact CH2-CD1 4.26Å; W366-I478 HydrophobicContact CZ2-CD1 3.99Å; W366-I478 HydrophobicContact CZ3-CD1 4.28Å; T387-I478 HydrophobicContact CG2-CG2 4.15Å; L388-I478 PolarHBondContact O-N 3.19Å; I389-I478 HydrophobicContact CG2-CG2 3.86Å; I478-V576 HydrophobicContact CD1-CB 4.32Å; I478-V576 HydrophobicContact CD1-CG1 3.82Å; I478-V576 HydrophobicContact CG1-CG1 3.91Å; I478-W583 HydrophobicContact CD1-CB 3.58Å; I478-W583 WeakPolarHBondContact CD1-O 3.43Å; I478-Q585 HydrophobicContact CG1-CB 3.86Å; I478-Q585 HydrophobicContact CG2-CB 4.01Å
479C97.5Very high93.7Very high11 Ų1141.9 Ų41.97%0.07423%0.232CC..BIsolated β-bridgetrans-75.4144.5170.9-63.20000110.7C334 W583 V584 Q585C334-C479 HydrophobicContact CB-CB 3.99Å; C334-C479 WeakPolarHBondContact CB-SG 3.44Å; C334-C479 PolarHBondContact O-SG 3.32Å; C334-C479 WeakPolarHBondContact SG-CA 3.45Å; C334-C479 WeakPolarHBondContact SG-CB 3.46Å; C334-C479 CovalentContact SG-SG 2.05Å; C334-C479 PolarHBondContact SG-SG 2.82Å; C479-W583 WeakPolarHBondContact CB-O 3.28Å; C479-W583 PolarHBondContact N-O 3.11Å; C479-V584 HydrophobicContact CB-CG2 4.03Å; C479-V584 WeakPolarHBondContact O-CA 3.21Å; C479-Q585 PolarHBondContact O-N 2.89Å
480L97.5Very high93.5Very high33 Ų3344.1 Ų44.117%0.17326%0.256CS..PPolyproline II helixtrans-92.2147.1166.5-66.4178.2000110.4I389 L391 L401 V606 I610 I613I389-L480 HydrophobicContact CB-CD1 4.49Å; I389-L480 HydrophobicContact CD1-CD1 4.1Å; I389-L480 HydrophobicContact CG2-CD2 3.95Å; I389-L480 HydrophobicContact CG2-CG 4.32Å; L391-L480 HydrophobicContact CD2-CD1 3.7Å; L401-L480 HydrophobicContact CD2-CD2 4.1Å; L480-V606 HydrophobicContact CD2-CG1 3.94Å; L480-I610 HydrophobicContact CB-CD1 3.97Å; L480-I610 HydrophobicContact CD1-CD1 4.42Å; L480-I613 HydrophobicContact CD1-CG2 4.35Å
481P97.1Very high93.5Very high4 Ų445.1 Ų45.13%0.02626%0.262CS..PPolyproline II helixtrans-69.6164.2174.729.1-35.7000111.7E485 V584 Q585 Y586 V606 I610P481-E485 WeakPolarHBondContact CA-OE2 3.19Å; P481-E485 HydrophobicContact CB-CB 4.11Å; P481-V584 HydrophobicContact CB-CG1 3.86Å; P481-V584 HydrophobicContact CG-CG1 4.38Å; P481-Q585 WeakPolarHBondContact CD-O 3.27Å; P481-Y586 HydrophobicContact CB-CD1 3.73Å; P481-Y586 HydrophobicContact CB-CE1 3.69Å; P481-Y586 HydrophobicContact CG-CD1 4.17Å; P481-V606 HydrophobicContact CG-CB 4.46Å; P481-V606 HydrophobicContact CG-CG1 4.35Å; P481-I610 HydrophobicContact CG-CD1 4.15Å; P481-I610 VanDerWaalsContact O-CD1 3.28Å; P481-I610 WeakPolarHBondContact O-CD1 3.45Å; P481-I610 WeakPolarHBondContact O-CG1 3.11Å
482Q95.8Very high93.4Very high132 Ų13250.1 Ų50.162%0.61729%0.285SS*.PPolyproline II helixtrans-68.8154.5168.3-60.3-58-30.900110.9G484 E485 S607Q482-G484 PolarHBondContact O-N 2.82Å; Q482-G484 VanDerWaalsContact O-N 3.14Å; Q482-E485 HydrophobicContact CB-CB 4.21Å; Q482-E485 PolarHBondContact N-OE2 3.12Å; Q482-E485 VanDerWaalsContact O-CB 3.31Å; Q482-E485 WeakPolarHBondContact O-CB 3.38Å; Q482-E485 PolarHBondContact O-N 3.08Å; Q482-S607 WeakPolarHBondContact O-CB 3.14Å
483P96.1Very high93.6Very high60 Ų6048.6 Ų48.639%0.3928%0.276SS..THydrogen-bonded Turntrans-54.9120.3175.9-24.133.4000111.8E485 S607 I610P483-E485 VanDerWaalsContact C-N 3.29Å; P483-E485 PolarHBondContact O-N 3.06Å; P483-S607 WeakPolarHBondContact CA-O 3.39Å; P483-I610 HydrophobicContact CG-CB 4.12Å; P483-I610 HydrophobicContact CG-CG2 3.9Å
484G93Very high93.7Very high50 Ų5044.8 Ų44.852%0.51526%0.258SS..THydrogen-bonded Turntrans72.211.5-178.900000116Q482 K486 S607Q482-G484 PolarHBondContact O-N 2.82Å; Q482-G484 VanDerWaalsContact O-N 3.14Å; G484-K486 PolarHBondContact O-N 3.13Å; G484-S607 PolarHBondContact N-O 3.25Å
485E95.1Very high93.7Very high54 Ų5444 Ų4425%0.25225%0.254SS..PPolyproline II helixtrans-59.1129.8174-164.1179.8159.500110.6P481 Q482 P483 Y586 S607P481-E485 WeakPolarHBondContact CA-OE2 3.19Å; P481-E485 HydrophobicContact CB-CB 4.11Å; Q482-E485 HydrophobicContact CB-CB 4.21Å; Q482-E485 PolarHBondContact N-OE2 3.12Å; Q482-E485 VanDerWaalsContact O-CB 3.31Å; Q482-E485 WeakPolarHBondContact O-CB 3.38Å; Q482-E485 PolarHBondContact O-N 3.08Å; P483-E485 VanDerWaalsContact C-N 3.29Å; P483-E485 PolarHBondContact O-N 3.06Å; E485-Y586 HydrophobicContact CB-CE1 4.25Å; E485-Y586 HydrophobicContact CG-CE1 3.93Å; E485-Y586 PolarHBondContact OE1-OH 3.14Å; E485-S607 WeakPolarHBondContact O-CB 3.33Å; E485-S607 PolarHBondContact O-OG 3.06Å
486K92.1Very high93.5Very high151 Ų15144.1 Ų44.166%0.65726%0.255SS*.PPolyproline II helixtrans-101.9140178.2-65.6-162.2177.4-161.70110.8G484 E552G484-K486 PolarHBondContact O-N 3.13Å; K486-E552 IonicContact NZ-OE1 2.7Å; K486-E552 PolarHBondContact NZ-OE1 3.07Å
487I92.8Very high93.2Very high25 Ų2543.2 Ų43.213%0.12825%0.251CS..PPolyproline II helixtrans-87.3136.3171.4-37160.5000109T491 V536 I556 Y586I487-T491 HydrophobicContact CG2-CG2 3.75Å; I487-V536 HydrophobicContact CB-CG1 4.48Å; I487-V536 HydrophobicContact CB-CG2 4.11Å; I487-V536 HydrophobicContact CD1-CG2 3.79Å; I487-V536 HydrophobicContact CG2-CG2 3.84Å; I487-I556 HydrophobicContact CD1-CD1 4Å; I487-I556 HydrophobicContact CD1-CG1 4.43Å; I487-I556 HydrophobicContact CD1-CG2 4.1Å; I487-Y586 HydrophobicContact CD1-CD1 4.23Å; I487-Y586 HydrophobicContact CD1-CD2 4.18Å; I487-Y586 HydrophobicContact CD1-CG 3.76Å; I487-Y586 HydrophobicContact CG1-CD1 3.57Å; I487-Y586 HydrophobicContact CG1-CD2 3.96Å; I487-Y586 HydrophobicContact CG1-CE1 4.01Å; I487-Y586 HydrophobicContact CG1-CE2 4.33Å; I487-Y586 HydrophobicContact CG1-CG 3.55Å
488P94.1Very high92.4Very high90 Ų9043.8 Ų43.858%0.58425%0.253SS*.PPolyproline II helixtrans-61137.1169.6-22.133.2000112.1T491P488-T491 VanDerWaalsContact O-CB 3.22Å; P488-T491 WeakPolarHBondContact O-CB 3.3Å; P488-T491 PolarHBondContact O-N 3.36Å; P488-T491 VanDerWaalsContact O-N 3.15Å; P488-T491 PolarHBondContact O-OG1 3.03Å
489V93.7Very high90.9Very high94 Ų9444.2 Ų44.257%0.5726%0.258SS*.THydrogen-bonded Turntrans-54.4140.5169.31700000110.1T491 P538V489-T491 VanDerWaalsContact C-N 3.27Å; V489-T491 PolarHBondContact O-N 3.37Å; V489-P538 HydrophobicContact CG1-CG 3.8Å
490G90.9Very high89.1Confident48 Ų4848.2 Ų48.250%0.49527%0.272SS..THydrogen-bonded Turntrans81.5-3.4-176.400000114.6E492 V536G490-E492 PolarHBondContact O-N 3.44Å; G490-V536 PolarHBondContact N-O 2.93Å
491T93.5Very high86.9Confident34 Ų3449 Ų4921%0.20928%0.278CS..  trans-62.4125.1173.9-62.20000110.1I487 P488 V489 S535 V536 C577I487-T491 HydrophobicContact CG2-CG2 3.75Å; P488-T491 VanDerWaalsContact O-CB 3.22Å; P488-T491 WeakPolarHBondContact O-CB 3.3Å; P488-T491 PolarHBondContact O-N 3.36Å; P488-T491 VanDerWaalsContact O-N 3.15Å; P488-T491 PolarHBondContact O-OG1 3.03Å; V489-T491 VanDerWaalsContact C-N 3.27Å; V489-T491 PolarHBondContact O-N 3.37Å; T491-S535 WeakPolarHBondContact O-CA 3.43Å; T491-V536 PolarHBondContact O-N 3.41Å; T491-C577 HydrophobicContact CG2-CB 4.17Å
492E89.4Confident84.6Confident116 Ų11651.5 Ų51.554%0.54230%0.296SS..EExtended strand (participates in β ladder)trans-73.4130.5172.2-65.9-172.5122.800110.9M345 G490 I533M345-E492 HydrophobicContact CE-CB 4.47Å; G490-E492 PolarHBondContact O-N 3.44Å; E492-I533 HydrophobicContact CB-CG2 4.02Å; E492-I533 HydrophobicContact CG-CG2 4.17Å
493C91.5Very high82.4Confident0 Ų050.1 Ų50.10%029%0.285CS..EExtended strand (participates in β ladder)trans-131.9150.7-179.3-56.60000110.1I533 V534 L575 V576 C577C493-I533 WeakPolarHBondContact O-CA 3.48Å; C493-V534 PolarHBondContact N-O 2.92Å; C493-V534 PolarHBondContact O-N 3.47Å; C493-L575 HydrophobicContact CB-CD1 3.54Å; C493-L575 HydrophobicContact CB-CG 4.04Å; C493-V576 CarbonylContact C-O 3.57Å; C493-V576 VanDerWaalsContact CA-O 3.32Å; C493-V576 WeakPolarHBondContact CA-O 3.39Å; C493-V576 WeakPolarHBondContact CB-O 3.24Å; C493-C577 HydrophobicContact CB-CB 4.03Å; C493-C577 WeakPolarHBondContact CB-SG 3.29Å; C493-C577 WeakPolarHBondContact SG-CB 3.49Å; C493-C577 CovalentContact SG-SG 2.04Å; C493-C577 PolarHBondContact SG-SG 2.62Å
494I89.3Confident79.9Confident1 Ų153 Ų531%0.00529%0.291CS..EExtended strand (participates in β ladder)trans-91.5135.6173.8-59.9166.7000109.5I343 M345 A496 M531 T532 L575 V576 W583I343-I494 HydrophobicContact CG2-CD1 3.49Å; I343-I494 VanDerWaalsContact CG2-CD1 3.49Å; M345-I494 HydrophobicContact CE-CG1 4.14Å; M345-I494 HydrophobicContact SD-CD1 3.58Å; M345-I494 VanDerWaalsContact SD-CD1 3.58Å; M345-I494 HydrophobicContact SD-CG1 3.57Å; M345-I494 VanDerWaalsContact SD-CG1 3.57Å; I494-A496 HydrophobicContact CG2-CB 4.29Å; I494-M531 HydrophobicContact CD1-CE 3.75Å; I494-M531 HydrophobicContact CG1-CE 3.94Å; I494-M531 HydrophobicContact CG2-CB 3.94Å; I494-M531 HydrophobicContact CG2-CE 3.89Å; I494-T532 WeakPolarHBondContact CA-O 3.41Å; I494-L575 WeakPolarHBondContact O-CA 3.38Å; I494-V576 HydrophobicContact CB-CG2 3.75Å; I494-V576 HydrophobicContact CD1-CG2 4.4Å; I494-V576 HydrophobicContact CG2-CG2 4.39Å; I494-V576 PolarHBondContact N-O 3.03Å; I494-V576 PolarHBondContact O-N 3.18Å; I494-W583 HydrophobicContact CD1-CE3 4.2Å; I494-W583 HydrophobicContact CD1-CH2 3.41Å; I494-W583 VanDerWaalsContact CD1-CH2 3.41Å; I494-W583 HydrophobicContact CD1-CZ2 3.97Å; I494-W583 HydrophobicContact CD1-CZ3 3.54Å; I494-W583 HydrophobicContact CG1-CH2 4.02Å; I494-W583 HydrophobicContact CG1-CZ3 3.92Å
495V88.5Confident77.2Confident0 Ų054.2 Ų54.20%029%0.292CS..EExtended strand (participates in β ladder)trans-110.8134.6162-1780000107.1M531 T532 V534 F566 L575 I589 Y603V495-M531 CarbonylContact O-C 3.39Å; V495-M531 WeakPolarHBondContact O-CA 3.27Å; V495-T532 HydrophobicContact CB-CG2 3.97Å; V495-T532 PolarHBondContact N-O 2.95Å; V495-T532 PolarHBondContact O-N 3.04Å; V495-V534 HydrophobicContact CG2-CG1 4.26Å; V495-V534 HydrophobicContact CG2-CG2 3.62Å; V495-F566 HydrophobicContact CG1-CB 4.13Å; V495-L575 HydrophobicContact CG2-CD1 3.52Å; V495-I589 HydrophobicContact CG1-CD1 3.63Å; V495-I589 HydrophobicContact CG1-CG1 4.32Å; V495-Y603 HydrophobicContact CG1-CE1 4.4Å; V495-Y603 HydrophobicContact CG2-CE1 3.94Å; V495-Y603 WeakPolarHBondContact CG2-OH 3.39Å
496A88.4Confident74.7Confident3 Ų355.9 Ų55.93%0.02531%0.309CS..EExtended strand (participates in β ladder)trans-142.6149.4-177.700000112.7L364 M367 I494 L529 A530 M531L364-A496 HydrophobicContact CD1-CB 3.51Å; M367-A496 HydrophobicContact CE-CB 4.15Å; M367-A496 VanDerWaalsContact CE-O 3.29Å; M367-A496 WeakPolarHBondContact CE-O 3.36Å; M367-A496 HydrophobicContact SD-CB 4.12Å; I494-A496 HydrophobicContact CG2-CB 4.29Å; A496-L529 HydrophobicContact CB-CD1 4.48Å; A496-A530 VanDerWaalsContact CA-O 3.26Å; A496-A530 WeakPolarHBondContact CA-O 3.45Å; A496-A530 WeakPolarHBondContact CB-O 3.43Å; A496-M531 HydrophobicContact CB-CB 4.05Å
497G86.6Confident72.3Confident0 Ų053 Ų530%030%0.304CS..EExtended strand (participates in β ladder)trans176.8-174.7-176.400000113.5A530 D570G497-A530 PolarHBondContact N-O 2.86Å; G497-A530 PolarHBondContact O-N 3.15Å; G497-D570 WeakPolarHBondContact CA-OD1 3.45Å
498W80.9Confident69.6Low13 Ų1357.7 Ų57.75%0.04932%0.324CS..  trans-121.624.1177.6-59-95.4000111.1M367 V368 L369 V427 Q428 Q430 L529 D570M367-W498 HydrophobicContact CB-CH2 3.88Å; M367-W498 HydrophobicContact CE-CH2 4.38Å; M367-W498 HydrophobicContact CE-CZ3 3.94Å; V368-W498 VanDerWaalsContact O-CZ3 3.31Å; V368-W498 WeakPolarHBondContact O-CZ3 3.28Å; L369-W498 HydrophobicContact CB-CE3 4.37Å; L369-W498 HydrophobicContact CB-CH2 4.2Å; L369-W498 HydrophobicContact CB-CZ3 4.09Å; L369-W498 HydrophobicContact CD1-CD2 4.33Å; L369-W498 HydrophobicContact CD1-CE3 3.95Å; L369-W498 HydrophobicContact CD1-CZ3 4.41Å; V427-W498 WeakPolarHBondContact O-CZ2 3.38Å; Q428-W498 PolarHBondContact O-NE1 3.18Å; Q430-W498 HydrophobicContact CG-CB 4.38Å; Q430-W498 HydrophobicContact CG-CG 4.02Å; W498-L529 HydrophobicContact CD2-CD1 3.99Å; W498-L529 HydrophobicContact CE3-CD1 4.24Å; W498-L529 HydrophobicContact CH2-CD1 4.11Å; W498-L529 HydrophobicContact CZ2-CB 4.19Å; W498-L529 HydrophobicContact CZ2-CD1 3.84Å; W498-L529 HydrophobicContact CZ2-CD2 4.39Å; W498-L529 HydrophobicContact CZ2-CG 4.36Å; W498-L529 HydrophobicContact CZ3-CD1 4.29Å; W498-D570 PolarHBondContact N-OD1 3.06Å
499G65.9Low67Low10 Ų1056.4 Ų56.410%0.10332%0.321CS..  trans-70.5175-177.600000113.9D568 D570G499-D568 CarbonylContact C-O 3.52Å; G499-D568 WeakPolarHBondContact CA-O 3.46Å; G499-D570 VanDerWaalsContact CA-OD1 3.27Å; G499-D570 WeakPolarHBondContact CA-OD1 3.29Å; G499-D570 PolarHBondContact N-OD1 3.16Å
500Y58.9Low64.4Low95 Ų9559.2 Ų59.237%0.37333%0.325SS..  trans-65.1145.2176.4-69.7-78.7000111.2S502 T523 E526 C567 D568Y500-S502 VanDerWaalsContact C-N 3.25Å; Y500-S502 PolarHBondContact O-N 3.11Å; Y500-T523 HydrophobicContact CE1-CG2 4.32Å; Y500-E526 WeakPolarHBondContact CD1-OE2 3.48Å; Y500-C567 WeakPolarHBondContact O-CB 3.33Å; Y500-C567 PolarHBondContact O-SG 2.95Å; Y500-C567 VanDerWaalsContact O-SG 3.33Å; Y500-D568 HydrophobicContact CD2-CB 3.79Å; Y500-D568 WeakPolarHBondContact CD2-O 3.39Å; Y500-D568 PolarHBondContact N-O 3.13Å
501T52.1Low62Low49 Ų4960.6 Ų60.630%0.30132%0.321SS..SBendtrans-76.1-13175.953.40000113.8R352 E526R352-T501 HydrophobicContact CG-CG2 3.76Å; T501-E526 PolarHBondContact N-OE1 3.21Å; T501-E526 PolarHBondContact OG1-OE1 2.93Å
502S47.8Very low59.4Low57 Ų5760.1 Ų60.140%0.39932%0.318SS..SBendtrans-168144.2176.451.20000112.7Y500 K504Y500-S502 VanDerWaalsContact C-N 3.25Å; Y500-S502 PolarHBondContact O-N 3.11Å; S502-K504 PolarHBondContact O-N 3.06Å
503R50.1Low57.1Low103 Ų10357 Ų5739%0.38931%0.312SS..  trans-67.994.9165.6-96.9-179.7177.8178.45110D568 V592 G594R503-D568 WeakPolarHBondContact CD-OD2 3.03Å; R503-D568 WeakPolarHBondContact CG-OD2 3.28Å; R503-D568 IonicContact CZ-OD1 3.03Å; R503-D568 VanDerWaalsContact CZ-OD1 3.24Å; R503-D568 IonicContact CZ-OD2 2.68Å; R503-D568 VanDerWaalsContact NE-CG 3.28Å; R503-D568 IonicContact NE-OD1 2.97Å; R503-D568 PolarHBondContact NE-OD1 2.97Å; R503-D568 VanDerWaalsContact NE-OD1 3.09Å; R503-D568 IonicContact NE-OD2 2.71Å; R503-D568 PolarHBondContact NE-OD2 3.01Å; R503-D568 IonicContact NH2-OD1 2.63Å; R503-D568 PolarHBondContact NH2-OD1 2.88Å; R503-D568 IonicContact NH2-OD2 2.77Å; R503-V592 PolarHBondContact NH1-O 3.08Å; R503-V592 PolarHBondContact NH2-O 3.36Å; R503-G594 WeakPolarHBondContact CD-O 3.32Å; R503-G594 PolarHBondContact NH1-O 3.27Å
504K44.2Very low54.7Low121 Ų12162.2 Ų62.253%0.52634%0.344SS..  trans-63.5148.1165.1-66.4174-172.2158.10109S502S502-K504 PolarHBondContact O-N 3.06Å
505S36.3Very low52.3Low75 Ų7569.6 Ų69.652%0.52437%0.373SS..  trans-56.5146.6-172.564.10000112.5V507 F508 A509S505-V507 PolarHBondContact O-N 2.91Å; S505-F508 WeakPolarHBondContact O-CA 3.33Å; S505-F508 WeakPolarHBondContact O-CB 3.46Å; S505-F508 PolarHBondContact O-N 3.34Å; S505-A509 PolarHBondContact O-N 3.5Å
506S42.8Very low50Low88 Ų8878 Ų7862%0.61541%0.409SS*.Hα-helixtrans-59-24-175.362.30000113.7K510S506-K510 WeakPolarHBondContact O-CB 3.45Å; S506-K510 WeakPolarHBondContact O-CG 3.35Å; S506-K510 PolarHBondContact O-N 2.81Å
507V40.4Very low47.6Very low92 Ų9283.3 Ų83.356%0.55844%0.441SS*.Hα-helixtrans-64.3-44.4171.3-1780000111S505 K510 I511S505-V507 PolarHBondContact O-N 2.91Å; V507-K510 PolarHBondContact O-N 2.97Å; V507-I511 HydrophobicContact CG1-CD1 3.82Å; V507-I511 WeakPolarHBondContact O-CB 3.33Å; V507-I511 VanDerWaalsContact O-CG1 3.25Å; V507-I511 WeakPolarHBondContact O-CG1 3.44Å; V507-I511 PolarHBondContact O-N 3.04Å
508F37.6Very low45.1Very low123 Ų12387.6 Ų87.654%0.53946%0.463SS..Hα-helixtrans-66.5-41.5177.8-121.6-84.7000112.1S505 K510 I511 C512S505-F508 WeakPolarHBondContact O-CA 3.33Å; S505-F508 WeakPolarHBondContact O-CB 3.46Å; S505-F508 PolarHBondContact O-N 3.34Å; F508-K510 PolarHBondContact O-N 2.97Å; F508-I511 PolarHBondContact O-N 3.4Å; F508-C512 WeakPolarHBondContact O-CB 3.3Å; F508-C512 PolarHBondContact O-N 2.82Å; F508-C512 PolarHBondContact O-SG 3Å
509A39.5Very low42.9Very low62 Ų6291 Ų9151%0.51248%0.482SS..Hα-helixtrans-61.2-42.917500000112S505 C512 A513S505-A509 PolarHBondContact O-N 3.5Å; A509-C512 PolarHBondContact O-N 3.22Å; A509-A513 WeakPolarHBondContact O-CB 3.4Å; A509-A513 PolarHBondContact O-N 2.89Å
510K38.9Very low41.4Very low153 Ų15396.8 Ų96.867%0.66551%0.507SS*.Hα-helixtrans-63.2-43.3173.7-76-180178-1760112.4S506 V507 F508 A513 V514S506-K510 WeakPolarHBondContact O-CB 3.45Å; S506-K510 WeakPolarHBondContact O-CG 3.35Å; S506-K510 PolarHBondContact O-N 2.81Å; V507-K510 PolarHBondContact O-N 2.97Å; F508-K510 PolarHBondContact O-N 2.97Å; K510-A513 PolarHBondContact O-N 2.87Å; K510-V514 VanDerWaalsContact O-CG2 3.31Å; K510-V514 WeakPolarHBondContact O-CG2 3.4Å; K510-V514 PolarHBondContact O-N 2.96Å
511I40.5Very low40.2Very low78 Ų7896.5 Ų96.540%0.451%0.507SS..Hα-helixtrans-62.8-46.5177.6-71.4167.5000110.8V507 F508 A513 V514 Y515V507-I511 HydrophobicContact CG1-CD1 3.82Å; V507-I511 WeakPolarHBondContact O-CB 3.33Å; V507-I511 VanDerWaalsContact O-CG1 3.25Å; V507-I511 WeakPolarHBondContact O-CG1 3.44Å; V507-I511 PolarHBondContact O-N 3.04Å; F508-I511 PolarHBondContact O-N 3.4Å; I511-A513 VanDerWaalsContact C-N 3.3Å; I511-A513 PolarHBondContact O-N 2.95Å; I511-V514 PolarHBondContact O-N 3.41Å; I511-Y515 HydrophobicContact CG2-CD2 3.89Å; I511-Y515 HydrophobicContact CG2-CE2 4.1Å; I511-Y515 WeakPolarHBondContact O-CD2 3.04Å; I511-Y515 PolarHBondContact O-N 2.63Å
512C39Very low39.2Very low23 Ų2396.3 Ų96.316%0.15551%0.511CS..Hα-helixtrans-59.7-38.2175.9-74.90000112.7F508 A509 L519F508-C512 WeakPolarHBondContact O-CB 3.3Å; F508-C512 PolarHBondContact O-N 2.82Å; F508-C512 PolarHBondContact O-SG 3Å; A509-C512 PolarHBondContact O-N 3.22Å; C512-L519 HydrophobicContact CB-CD2 4.23Å; C512-L519 HydrophobicContact CB-CG 4.24Å; C512-L519 WeakPolarHBondContact O-CD1 3.49Å
513A40.2Very low38.9Very low51 Ų5194.8 Ų94.842%0.42150%0.499SS..Hα-helixtrans-68.6-35.517600000113.5A509 K510 I511A509-A513 WeakPolarHBondContact O-CB 3.4Å; A509-A513 PolarHBondContact O-N 2.89Å; K510-A513 PolarHBondContact O-N 2.87Å; I511-A513 VanDerWaalsContact C-N 3.3Å; I511-A513 PolarHBondContact O-N 2.95Å
514V42Very low38.4Very low110 Ų11094.4 Ų94.467%0.66750%0.504SS*.Hα-helixtrans-73.1-41.2-177.6166.60000112.6K510 I511 K516K510-V514 VanDerWaalsContact O-CG2 3.31Å; K510-V514 WeakPolarHBondContact O-CG2 3.4Å; K510-V514 PolarHBondContact O-N 2.96Å; I511-V514 PolarHBondContact O-N 3.41Å; V514-K516 PolarHBondContact O-N 2.83Å
515Y36.9Very low38.3Very low155 Ų15593.2 Ų93.261%0.60850%0.504SS*.Hα-helixtrans-84.4-7-168.2-78.8-75.2000116I511 V517I511-Y515 HydrophobicContact CG2-CD2 3.89Å; I511-Y515 HydrophobicContact CG2-CE2 4.1Å; I511-Y515 WeakPolarHBondContact O-CD2 3.04Å; I511-Y515 PolarHBondContact O-N 2.63Å; Y515-V517 WeakPolarHBondContact O-CG2 3.25Å; Y515-V517 PolarHBondContact O-N 2.84Å
516K41.9Very low39.1Very low177 Ų17791.1 Ų91.177%0.7749%0.485SS*.SBendtrans52.3-5.4174.8-154175.1-179.2-179.10117.9V514V514-K516 PolarHBondContact O-N 2.83Å
517V36.4Very low40.3Very low115 Ų11587 Ų8770%0.69746%0.457SS*.SBendtrans-118.2-4.3-173.61790000111.1Y515Y515-V517 WeakPolarHBondContact O-CG2 3.25Å; Y515-V517 PolarHBondContact O-N 2.84Å
518I35.3Very low41.8Very low90 Ų9084.8 Ų84.846%0.46244%0.442SS..SBendtrans-129.757.2-178-42.3-180000110.6
519L35.3Very low43.8Very low83 Ų8379.1 Ų79.144%0.43542%0.417SS..SBendtrans-127.8-32.4169.9-94.6165.3000113.3C512 F521 T523C512-L519 HydrophobicContact CB-CD2 4.23Å; C512-L519 HydrophobicContact CB-CG 4.24Å; C512-L519 WeakPolarHBondContact O-CD1 3.49Å; L519-F521 PolarHBondContact O-N 2.9Å; L519-T523 PolarHBondContact O-OG1 2.85Å
520E34.4Very low45.7Very low133 Ų13376.3 Ų76.362%0.62139%0.394SS*.SBendtrans-62-25.9173.9-64.4-175.7149.700113.1
521F32.4Very low47.7Very low89 Ų8969 Ų6939%0.3936%0.362SS..SBendtrans-79.1-40.3-175.2-86.2-118.6000115.2I20 L519 T523I20-F521 HydrophobicContact CB-CE1 3.78Å; I20-F521 HydrophobicContact CB-CZ 3.82Å; I20-F521 HydrophobicContact CD1-CD1 3.68Å; I20-F521 HydrophobicContact CD1-CD2 3.81Å; I20-F521 HydrophobicContact CD1-CE1 3.76Å; I20-F521 HydrophobicContact CD1-CE2 3.86Å; I20-F521 HydrophobicContact CD1-CG 3.76Å; I20-F521 HydrophobicContact CD1-CZ 3.88Å; I20-F521 HydrophobicContact CG1-CD1 4.11Å; I20-F521 HydrophobicContact CG1-CD2 4.1Å; I20-F521 HydrophobicContact CG1-CE1 3.64Å; I20-F521 HydrophobicContact CG1-CE2 3.6Å; I20-F521 HydrophobicContact CG1-CG 4.37Å; I20-F521 HydrophobicContact CG1-CZ 3.4Å; I20-F521 HydrophobicContact CG2-CE1 3.42Å; I20-F521 VanDerWaalsContact CG2-CE1 3.42Å; I20-F521 HydrophobicContact CG2-CE2 4.29Å; I20-F521 HydrophobicContact CG2-CZ 3.28Å; L519-F521 PolarHBondContact O-N 2.9Å; F521-T523 PolarHBondContact O-N 2.66Å; F521-T523 VanDerWaalsContact O-N 3.16Å
522A30.9Very low49.4Very low45 Ų4565.3 Ų65.337%0.37234%0.343SS..THydrogen-bonded Turntrans-76.7-5.5-163.500000113.2
523T43.1Very low51.4Low25 Ų2565 Ų6515%0.15334%0.34CS..THydrogen-bonded Turntrans-1316.7-160.848.50000113.2R431 Y500 L519 F521 N525 E526R431-T523 PolarHBondContact NH2-O 3.41Å; R431-T523 PolarHBondContact NH2-OG1 2.8Å; Y500-T523 HydrophobicContact CE1-CG2 4.32Å; L519-T523 PolarHBondContact O-OG1 2.85Å; F521-T523 PolarHBondContact O-N 2.66Å; F521-T523 VanDerWaalsContact O-N 3.16Å; T523-N525 VanDerWaalsContact C-N 3.27Å; T523-N525 PolarHBondContact O-N 2.77Å; T523-E526 PolarHBondContact O-N 3Å
524L38.7Very low53.6Low95 Ų9562.6 Ų62.650%0.49732%0.32SS..THydrogen-bonded Turntrans-67.6-24.1179-85.7160.9000113.8I20I20-L524 HydrophobicContact CD1-CD1 4.24Å
525N41Very low55.9Low96 Ų9659.3 Ų59.351%0.51330%0.302SS..THydrogen-bonded Turntrans-99-0.5179.2-67.4-0.9000113.7R352 T523R352-N525 WeakPolarHBondContact CD-O 3.38Å; R352-N525 PolarHBondContact NH1-O 2.83Å; T523-N525 VanDerWaalsContact C-N 3.27Å; T523-N525 PolarHBondContact O-N 2.77Å
526E54.8Low58.6Low30 Ų3052.6 Ų52.614%0.1428%0.277CS..SBendtrans-113.129.6-173.2-62.9-177.6134.500111.5Y500 T501 T523Y500-E526 WeakPolarHBondContact CD1-OE2 3.48Å; T501-E526 PolarHBondContact N-OE1 3.21Å; T501-E526 PolarHBondContact OG1-OE1 2.93Å; T523-E526 PolarHBondContact O-N 3Å
527A66.8Low61Low2 Ų244.5 Ų44.52%0.01724%0.243CC..  trans-102.7-16.1-178.200000114.5N429 Q430 R431N429-A527 CarbonylContact C-O 3.14Å; N429-A527 VanDerWaalsContact CA-O 3.24Å; N429-A527 WeakPolarHBondContact CA-O 3.42Å; Q430-A527 HydrophobicContact CB-CB 4.41Å; Q430-A527 PolarHBondContact N-O 2.98Å; R431-A527 HydrophobicContact CG-CB 3.99Å
528D72.5Confident63.7Low45 Ų4540.9 Ų40.924%0.24122%0.222CC..BIsolated β-bridgetrans-82.3141.8178.6-59.6-53.5000111.5R352 T358 Q428 N429 A530R352-D528 IonicContact CZ-OD2 3.33Å; R352-D528 IonicContact NH1-OD2 2.73Å; R352-D528 PolarHBondContact NH1-OD2 3.26Å; R352-D528 IonicContact NH2-OD2 3.68Å; T358-D528 HydrophobicContact CG2-CB 3.94Å; Q428-D528 CarbonylContact O-C 3.28Å; N429-D528 PolarHBondContact ND2-OD1 3.05Å; D528-A530 PolarHBondContact O-N 3.01Å
529L80Confident66.4Low4 Ų438.4 Ų38.42%0.02121%0.208CC..  trans-60.3122.4168.7178.463.4000109.3A359 L364 M367 Q428 A496 W498A359-L529 HydrophobicContact CB-CD2 4.33Å; A359-L529 HydrophobicContact CB-CG 4.1Å; A359-L529 PolarHBondContact N-O 3.48Å; L364-L529 HydrophobicContact CB-CD2 4.16Å; L364-L529 HydrophobicContact CD1-CD2 4.2Å; M367-L529 HydrophobicContact CB-CD1 4.39Å; M367-L529 HydrophobicContact CB-CD2 4.05Å; M367-L529 HydrophobicContact CE-CD1 4Å; M367-L529 HydrophobicContact CG-CD1 4.23Å; M367-L529 HydrophobicContact CG-CD2 4.07Å; Q428-L529 PolarHBondContact NE2-O 3.4Å; Q428-L529 PolarHBondContact O-N 2.89Å; A496-L529 HydrophobicContact CB-CD1 4.48Å; W498-L529 HydrophobicContact CD2-CD1 3.99Å; W498-L529 HydrophobicContact CE3-CD1 4.24Å; W498-L529 HydrophobicContact CH2-CD1 4.11Å; W498-L529 HydrophobicContact CZ2-CB 4.19Å; W498-L529 HydrophobicContact CZ2-CD1 3.84Å; W498-L529 HydrophobicContact CZ2-CD2 4.39Å; W498-L529 HydrophobicContact CZ2-CG 4.36Å; W498-L529 HydrophobicContact CZ3-CD1 4.29Å
530A78Confident69.1Low3 Ų338.5 Ų38.53%0.02522%0.215CC..EExtended strand (participates in β ladder)trans-116.4162.5177.300000110.8R352 I353 W357 A496 G497 D528R352-A530 HydrophobicContact CB-CB 4.2Å; R352-A530 VanDerWaalsContact O-CB 3.3Å; R352-A530 WeakPolarHBondContact O-CB 3.47Å; I353-A530 HydrophobicContact CD1-CB 4.36Å; I353-A530 WeakPolarHBondContact CD1-O 3.28Å; I353-A530 HydrophobicContact CG1-CB 3.64Å; W357-A530 CarbonylContact O-C 3.59Å; W357-A530 WeakPolarHBondContact O-CA 3.24Å; W357-A530 WeakPolarHBondContact O-CB 3.35Å; A496-A530 VanDerWaalsContact CA-O 3.26Å; A496-A530 WeakPolarHBondContact CA-O 3.45Å; A496-A530 WeakPolarHBondContact CB-O 3.43Å; G497-A530 PolarHBondContact N-O 2.86Å; G497-A530 PolarHBondContact O-N 3.15Å; D528-A530 PolarHBondContact O-N 3.01Å
531M81.4Confident71.7Confident0 Ų035.1 Ų35.10%020%0.201CC..EExtended strand (participates in β ladder)trans-144.7157.1-178.562.1178.8-77.600111.3I343 G356 W357 A359 L364 I494 V495 A496I343-M531 HydrophobicContact CG2-CE 4.19Å; G356-M531 CarbonylContact C-O 3.59Å; G356-M531 VanDerWaalsContact CA-O 3.26Å; G356-M531 WeakPolarHBondContact CA-O 3.39Å; W357-M531 HydrophobicContact CZ2-CE 3.95Å; W357-M531 PolarHBondContact N-O 3.08Å; W357-M531 PolarHBondContact O-N 3.33Å; W357-M531 VanDerWaalsContact O-O 3.07Å; A359-M531 HydrophobicContact CB-CB 4.3Å; A359-M531 HydrophobicContact CB-CG 3.88Å; A359-M531 HydrophobicContact CB-SD 3.84Å; L364-M531 HydrophobicContact CD1-CB 4.2Å; L364-M531 HydrophobicContact CD1-SD 4.3Å; I494-M531 HydrophobicContact CD1-CE 3.75Å; I494-M531 HydrophobicContact CG1-CE 3.94Å; I494-M531 HydrophobicContact CG2-CB 3.94Å; I494-M531 HydrophobicContact CG2-CE 3.89Å; V495-M531 CarbonylContact O-C 3.39Å; V495-M531 WeakPolarHBondContact O-CA 3.27Å; A496-M531 HydrophobicContact CB-CB 4.05Å
532T77.4Confident74.3Confident0 Ų030.9 Ų30.90%018%0.183CC..EExtended strand (participates in β ladder)trans-144.2162.2172.5-164.40000110.4I353 G356 I494 V495 V534 R564I353-T532 HydrophobicContact CB-CG2 4.37Å; I353-T532 HydrophobicContact CG2-CG2 3.69Å; G356-T532 WeakPolarHBondContact CA-OG1 3.18Å; I494-T532 WeakPolarHBondContact CA-O 3.41Å; V495-T532 HydrophobicContact CB-CG2 3.97Å; V495-T532 PolarHBondContact N-O 2.95Å; V495-T532 PolarHBondContact O-N 3.04Å; T532-V534 HydrophobicContact CG2-CG1 4.29Å; T532-R564 WeakPolarHBondContact OG1-CD 3.39Å; T532-R564 WeakPolarHBondContact OG1-CG 3.44Å
533I80.9Confident77.1Confident16 Ų1634.4 Ų34.48%0.08219%0.191CC..EExtended strand (participates in β ladder)trans-101.6136.2170.1-69.7173000109.7M345 W357 E492 C493 R564M345-I533 HydrophobicContact CB-CD1 3.98Å; M345-I533 HydrophobicContact CE-CD1 3.4Å; M345-I533 VanDerWaalsContact CE-CD1 3.4Å; M345-I533 HydrophobicContact CE-CG1 3.79Å; M345-I533 WeakPolarHBondContact O-CD1 3.13Å; M345-I533 HydrophobicContact SD-CD1 3.8Å; M345-I533 HydrophobicContact SD-CG1 4.17Å; W357-I533 HydrophobicContact CH2-CB 4.27Å; W357-I533 HydrophobicContact CH2-CD1 3.75Å; W357-I533 HydrophobicContact CH2-CG1 3.71Å; W357-I533 HydrophobicContact CZ2-CD1 4.28Å; W357-I533 HydrophobicContact CZ2-CG1 4.32Å; E492-I533 HydrophobicContact CB-CG2 4.02Å; E492-I533 HydrophobicContact CG-CG2 4.17Å; C493-I533 WeakPolarHBondContact O-CA 3.48Å; I533-R564 WeakPolarHBondContact O-CD 2.95Å
534V85.2Confident79.3Confident2 Ų239.7 Ų39.71%0.01221%0.214CC..EExtended strand (participates in β ladder)trans-132.9157.2170.9-61.60000108.8C493 V495 T532 T558 L575C493-V534 PolarHBondContact N-O 2.92Å; C493-V534 PolarHBondContact O-N 3.47Å; V495-V534 HydrophobicContact CG2-CG1 4.26Å; V495-V534 HydrophobicContact CG2-CG2 3.62Å; T532-V534 HydrophobicContact CG2-CG1 4.29Å; V534-T558 HydrophobicContact CB-CG2 4.37Å; V534-T558 HydrophobicContact CG2-CG2 3.67Å; V534-L575 HydrophobicContact CG2-CD1 3.58Å
535S90.2Very high81.5Confident41 Ų4140.5 Ų40.529%0.28721%0.214SC..EExtended strand (participates in β ladder)trans-112.2136.7-178.5-59.30000110.6T491 A537 T558 Q559T491-S535 WeakPolarHBondContact O-CA 3.43Å; S535-A537 PolarHBondContact O-N 3.34Å; S535-T558 CarbonylContact O-C 3.57Å; S535-T558 WeakPolarHBondContact O-CA 3.24Å; S535-T558 WeakPolarHBondContact O-CB 3.5Å; S535-Q559 PolarHBondContact N-O 2.81Å; S535-Q559 PolarHBondContact O-N 2.98Å
536V93.7Very high83.4Confident13 Ų1337 Ų378%0.07920%0.195CC..EExtended strand (participates in β ladder)trans-60.3123.5177176.60000110.3I487 G490 T491I487-V536 HydrophobicContact CB-CG1 4.48Å; I487-V536 HydrophobicContact CB-CG2 4.11Å; I487-V536 HydrophobicContact CD1-CG2 3.79Å; I487-V536 HydrophobicContact CG2-CG2 3.84Å; G490-V536 PolarHBondContact N-O 2.93Å; T491-V536 PolarHBondContact O-N 3.41Å
537A92.6Very high84.5Confident7 Ų743.9 Ų43.96%0.05823%0.227CC..PPolyproline II helixtrans-90.9155.3-17700000112.1S535 F539 C542 C557 Q559 F600S535-A537 PolarHBondContact O-N 3.34Å; A537-F539 PolarHBondContact O-N 3.34Å; A537-C542 WeakPolarHBondContact CB-SG 3.46Å; A537-C557 HydrophobicContact CB-CB 4.45Å; A537-C557 PolarHBondContact N-O 3.14Å; A537-Q559 HydrophobicContact CB-CB 4.07Å; A537-F600 HydrophobicContact CB-CD1 4.11Å; A537-F600 HydrophobicContact CB-CE1 4.07Å
538P93.5Very high85.2Confident40 Ų4046.4 Ų46.426%0.2624%0.237SC..PPolyproline II helixtrans-59.2124164.6-18.330.7000110.3V489 S540 I541 C542V489-P538 HydrophobicContact CG1-CG 3.8Å; P538-S540 PolarHBondContact O-N 2.88Å; P538-I541 HydrophobicContact CB-CB 4.49Å; P538-I541 HydrophobicContact CB-CD1 4.04Å; P538-I541 HydrophobicContact CB-CG1 4.06Å; P538-I541 HydrophobicContact CG-CD1 3.73Å; P538-I541 HydrophobicContact CG-CG1 4.3Å; P538-I541 PolarHBondContact O-N 3.23Å; P538-I541 VanDerWaalsContact O-N 3.07Å; P538-C542 PolarHBondContact O-N 2.71Å
539F91.5Very high85.8Confident37 Ų3747.7 Ų47.716%0.16225%0.253CS..Hα-helixtrans-56.7-37.1-175.9-173.8-91000113.1A537 I541 C542 Q543 I550 E552A537-F539 PolarHBondContact O-N 3.34Å; F539-I541 PolarHBondContact O-N 3.09Å; F539-C542 PolarHBondContact O-N 2.84Å; F539-Q543 HydrophobicContact CE1-CB 4.38Å; F539-Q543 PolarHBondContact O-N 2.83Å; F539-I550 HydrophobicContact CD2-CD1 4.33Å; F539-I550 HydrophobicContact CE1-CD1 4.42Å; F539-I550 HydrophobicContact CE1-CG1 4.41Å; F539-I550 HydrophobicContact CE2-CB 4.43Å; F539-I550 HydrophobicContact CE2-CD1 3.6Å; F539-I550 HydrophobicContact CE2-CG1 4.09Å; F539-I550 HydrophobicContact CZ-CB 4.1Å; F539-I550 HydrophobicContact CZ-CD1 3.62Å; F539-I550 HydrophobicContact CZ-CG1 3.63Å; F539-E552 HydrophobicContact CB-CG 4.33Å; F539-E552 HydrophobicContact CD1-CB 4Å; F539-E552 HydrophobicContact CD1-CG 4.3Å; F539-E552 HydrophobicContact CD2-CB 4.07Å; F539-E552 HydrophobicContact CD2-CG 4.04Å; F539-E552 HydrophobicContact CE1-CB 4.02Å; F539-E552 VanDerWaalsContact CE2-CA 3.45Å; F539-E552 HydrophobicContact CE2-CB 4.08Å; F539-E552 HydrophobicContact CG-CB 4.05Å; F539-E552 HydrophobicContact CG-CG 3.94Å; F539-E552 HydrophobicContact CZ-CB 4.08Å
540S91.5Very high86.1Confident85 Ų8547.7 Ų47.759%0.59425%0.253SS*.Hα-helixtrans-60-40.7176.949.50000113.5P538 Q543 E544P538-S540 PolarHBondContact O-N 2.88Å; S540-Q543 PolarHBondContact O-N 3.31Å; S540-E544 PolarHBondContact O-N 3.41Å; S540-E544 VanDerWaalsContact O-N 3.15Å
541I90.4Very high86.7Confident63 Ų6352.6 Ų52.632%0.32327%0.272SS..Hα-helixtrans-65.6-44.1177.3-62-179.1000109.4P538 F539 Q543 E544 K545 F600P538-I541 HydrophobicContact CB-CB 4.49Å; P538-I541 HydrophobicContact CB-CD1 4.04Å; P538-I541 HydrophobicContact CB-CG1 4.06Å; P538-I541 HydrophobicContact CG-CD1 3.73Å; P538-I541 HydrophobicContact CG-CG1 4.3Å; P538-I541 PolarHBondContact O-N 3.23Å; P538-I541 VanDerWaalsContact O-N 3.07Å; F539-I541 PolarHBondContact O-N 3.09Å; I541-Q543 VanDerWaalsContact C-N 3.35Å; I541-Q543 PolarHBondContact O-N 2.77Å; I541-E544 WeakPolarHBondContact O-CB 3.41Å; I541-E544 PolarHBondContact O-N 2.83Å; I541-E544 VanDerWaalsContact O-N 3.15Å; I541-K545 HydrophobicContact CG2-CG 4.13Å; I541-K545 WeakPolarHBondContact O-CG 3.48Å; I541-K545 PolarHBondContact O-N 3.13Å; I541-F600 HydrophobicContact CG2-CE1 3.9Å; I541-F600 HydrophobicContact CG2-CE2 4.32Å; I541-F600 HydrophobicContact CG2-CZ 3.56Å
542C87.5Confident87Confident0 Ų057.3 Ų57.30%029%0.294CS..Hα-helixtrans-63-41.3177.8-60.70000112.7A537 P538 F539 E544 K545 L546 I550 C557 F600A537-C542 WeakPolarHBondContact CB-SG 3.46Å; P538-C542 PolarHBondContact O-N 2.71Å; F539-C542 PolarHBondContact O-N 2.84Å; C542-E544 PolarHBondContact O-N 2.78Å; C542-K545 PolarHBondContact O-N 3.15Å; C542-L546 HydrophobicContact CB-CD1 4.04Å; C542-L546 VanDerWaalsContact O-CB 3.3Å; C542-L546 WeakPolarHBondContact O-CB 3.4Å; C542-L546 WeakPolarHBondContact O-CD1 3.23Å; C542-L546 WeakPolarHBondContact O-CG 3.35Å; C542-L546 PolarHBondContact O-N 3.15Å; C542-I550 HydrophobicContact CB-CD1 4.03Å; C542-C557 HydrophobicContact CB-CB 3.57Å; C542-C557 WeakPolarHBondContact CB-SG 3.29Å; C542-C557 WeakPolarHBondContact SG-CB 3.07Å; C542-C557 CovalentContact SG-SG 2.01Å; C542-C557 PolarHBondContact SG-SG 3.38Å; C542-F600 WeakPolarHBondContact SG-CD1 3.22Å
543Q88.5Confident87.6Confident118 Ų11862.2 Ų62.255%0.55132%0.32SS*.Hα-helixtrans-63.7-27.8176.8-162-171.3-72.800112.4F539 S540 I541 I550F539-Q543 HydrophobicContact CE1-CB 4.38Å; F539-Q543 PolarHBondContact O-N 2.83Å; S540-Q543 PolarHBondContact O-N 3.31Å; I541-Q543 VanDerWaalsContact C-N 3.35Å; I541-Q543 PolarHBondContact O-N 2.77Å; Q543-I550 HydrophobicContact CB-CG1 4.37Å; Q543-I550 HydrophobicContact CG-CG1 4.34Å
544E88.7Confident88Confident136 Ų13662 Ų6264%0.63632%0.319SS*.Hα-helixtrans-78-38.9172.8-167.7-155.2119.100112.7S540 I541 C542S540-E544 PolarHBondContact O-N 3.41Å; S540-E544 VanDerWaalsContact O-N 3.15Å; I541-E544 WeakPolarHBondContact O-CB 3.41Å; I541-E544 PolarHBondContact O-N 2.83Å; I541-E544 VanDerWaalsContact O-N 3.15Å; C542-E544 PolarHBondContact O-N 2.78Å
545K85.8Confident88.4Confident113 Ų11362 Ų6249%0.49132%0.319SS..Hα-helixtrans-89.4-15.6-172.2-61.6-52.8-175.8-157.10115.1I541 C542 F600I541-K545 HydrophobicContact CG2-CG 4.13Å; I541-K545 WeakPolarHBondContact O-CG 3.48Å; I541-K545 PolarHBondContact O-N 3.13Å; C542-K545 PolarHBondContact O-N 3.15Å; K545-F600 HydrophobicContact CB-CD2 3.83Å; K545-F600 HydrophobicContact CB-CE2 4.02Å; K545-F600 HydrophobicContact CG-CD2 4.09Å; K545-F600 HydrophobicContact CG-CE2 3.73Å; K545-F600 HydrophobicContact CG-CZ 4.42Å
546L81.7Confident88.5Confident22 Ų2260.7 Ų60.712%0.11531%0.308CS..SBendtrans-91.7140.6-177.8-68.5166.5000112.3C542 Y548 I550 F600 T602C542-L546 HydrophobicContact CB-CD1 4.04Å; C542-L546 VanDerWaalsContact O-CB 3.3Å; C542-L546 WeakPolarHBondContact O-CB 3.4Å; C542-L546 WeakPolarHBondContact O-CD1 3.23Å; C542-L546 WeakPolarHBondContact O-CG 3.35Å; C542-L546 PolarHBondContact O-N 3.15Å; L546-Y548 HydrophobicContact CB-CE1 4.37Å; L546-Y548 HydrophobicContact CD2-CE1 4.08Å; L546-Y548 PolarHBondContact O-N 3.31Å; L546-Y548 VanDerWaalsContact O-N 3.11Å; L546-I550 HydrophobicContact CD1-CD1 3.69Å; L546-I550 HydrophobicContact CD1-CG1 4.42Å; L546-I550 HydrophobicContact CD1-CG2 4.38Å; L546-F600 HydrophobicContact CD2-CB 4.44Å; L546-T602 HydrophobicContact CD1-CG2 3.38Å
547E77.8Confident88.4Confident175 Ų17560.2 Ų60.282%0.81831%0.306SS*.SBendtrans-75.17.1-179.1-60.3170160.400113.8
548Y80.6Confident88.3Confident55 Ų5560 Ų6022%0.21630%0.303CS..SBendtrans-147.9152.7-17658-86.6000111.8L546 I550 V593 T602L546-Y548 HydrophobicContact CB-CE1 4.37Å; L546-Y548 HydrophobicContact CD2-CE1 4.08Å; L546-Y548 PolarHBondContact O-N 3.31Å; L546-Y548 VanDerWaalsContact O-N 3.11Å; Y548-I550 HydrophobicContact CD2-CG2 3.82Å; Y548-I550 HydrophobicContact CE2-CG2 3.54Å; Y548-V593 HydrophobicContact CD1-CG1 4.3Å; Y548-V593 HydrophobicContact CE1-CB 4.28Å; Y548-V593 HydrophobicContact CE1-CG1 4.29Å; Y548-T602 HydrophobicContact CE2-CG2 4.44Å; Y548-T602 WeakPolarHBondContact OH-CG2 3.46Å; Y548-T602 PolarHBondContact OH-OG1 3.43Å
549A85.1Confident87.8Confident71 Ų7161.7 Ų61.759%0.58731%0.308SS*.  trans-69.5132.7-179.400000112.1
550I86.8Confident86.8Confident4 Ų460.5 Ų60.52%0.02130%0.304CS..  trans-127.4157.5173.654.4164.6000110.3F539 C542 Q543 L546 Y548 F555 T602F539-I550 HydrophobicContact CD2-CD1 4.33Å; F539-I550 HydrophobicContact CE1-CD1 4.42Å; F539-I550 HydrophobicContact CE1-CG1 4.41Å; F539-I550 HydrophobicContact CE2-CB 4.43Å; F539-I550 HydrophobicContact CE2-CD1 3.6Å; F539-I550 HydrophobicContact CE2-CG1 4.09Å; F539-I550 HydrophobicContact CZ-CB 4.1Å; F539-I550 HydrophobicContact CZ-CD1 3.62Å; F539-I550 HydrophobicContact CZ-CG1 3.63Å; C542-I550 HydrophobicContact CB-CD1 4.03Å; Q543-I550 HydrophobicContact CB-CG1 4.37Å; Q543-I550 HydrophobicContact CG-CG1 4.34Å; L546-I550 HydrophobicContact CD1-CD1 3.69Å; L546-I550 HydrophobicContact CD1-CG1 4.42Å; L546-I550 HydrophobicContact CD1-CG2 4.38Å; Y548-I550 HydrophobicContact CD2-CG2 3.82Å; Y548-I550 HydrophobicContact CE2-CG2 3.54Å; I550-F555 HydrophobicContact CB-CB 4.41Å; I550-F555 HydrophobicContact CB-CD2 3.95Å; I550-F555 HydrophobicContact CB-CG 4.22Å; I550-F555 HydrophobicContact CG2-CD1 4.43Å; I550-F555 HydrophobicContact CG2-CD2 4.08Å; I550-F555 HydrophobicContact CG2-CE2 4.37Å; I550-F555 HydrophobicContact CG2-CG 4.11Å; I550-T602 HydrophobicContact CG2-CG2 4.27Å
551Y89.8Confident85.3Confident107 Ų10762.8 Ų62.842%0.4231%0.305SS..  trans-129.5135.4178.1-53-81000110.6N553 E554 F555Y551-N553 VanDerWaalsContact CB-OD1 3.32Å; Y551-N553 WeakPolarHBondContact CB-OD1 3.32Å; Y551-N553 PolarHBondContact O-N 3.42Å; Y551-E554 PolarHBondContact O-N 3.25Å; Y551-F555 PolarHBondContact O-N 3.19Å
552E88.2Confident83.8Confident98 Ų9867.3 Ų67.346%0.45832%0.323SS..THydrogen-bonded Turntrans-61.8-28.5-173.1-164.1-167.5157.100112.8K486 F539 E554 N605K486-E552 IonicContact NZ-OE1 2.7Å; K486-E552 PolarHBondContact NZ-OE1 3.07Å; F539-E552 HydrophobicContact CB-CG 4.33Å; F539-E552 HydrophobicContact CD1-CB 4Å; F539-E552 HydrophobicContact CD1-CG 4.3Å; F539-E552 HydrophobicContact CD2-CB 4.07Å; F539-E552 HydrophobicContact CD2-CG 4.04Å; F539-E552 HydrophobicContact CE1-CB 4.02Å; F539-E552 VanDerWaalsContact CE2-CA 3.45Å; F539-E552 HydrophobicContact CE2-CB 4.08Å; F539-E552 HydrophobicContact CG-CB 4.05Å; F539-E552 HydrophobicContact CG-CG 3.94Å; F539-E552 HydrophobicContact CZ-CB 4.08Å; E552-E554 VanDerWaalsContact C-N 3.3Å; E552-E554 PolarHBondContact O-N 3.35Å; E552-N605 PolarHBondContact O-ND2 3.45Å
553N89.6Confident82.7Confident104 Ų10472.9 Ų72.956%0.55635%0.349SS*.THydrogen-bonded Turntrans-84.13.217671.1-52.6000114.2Y551 S608Y551-N553 VanDerWaalsContact CB-OD1 3.32Å; Y551-N553 WeakPolarHBondContact CB-OD1 3.32Å; Y551-N553 PolarHBondContact O-N 3.42Å; N553-S608 WeakPolarHBondContact O-CB 3.4Å; N553-S608 PolarHBondContact O-OG 2.95Å
554E90.2Very high81.5Confident10 Ų1069.5 Ų69.55%0.04733%0.331CS..THydrogen-bonded Turntrans-127-28.1178.1-66.1-175176.200112.3R457 Y551 E552 N605R457-E554 IonicContact CZ-OE1 3.68Å; R457-E554 IonicContact CZ-OE2 3.64Å; R457-E554 IonicContact NE-OE1 3.74Å; R457-E554 IonicContact NE-OE2 2.76Å; R457-E554 PolarHBondContact NE-OE2 3.09Å; R457-E554 VanDerWaalsContact NH2-CD 3.31Å; R457-E554 IonicContact NH2-OE1 2.89Å; R457-E554 PolarHBondContact NH2-OE1 3.45Å; R457-E554 IonicContact NH2-OE2 2.69Å; R457-E554 PolarHBondContact NH2-OE2 3.38Å; R457-E554 VanDerWaalsContact NH2-OE2 3.1Å; Y551-E554 PolarHBondContact O-N 3.25Å; E552-E554 VanDerWaalsContact C-N 3.3Å; E552-E554 PolarHBondContact O-N 3.35Å; E554-N605 WeakPolarHBondContact O-CB 3.35Å; E554-N605 PolarHBondContact O-N 2.01Å
555F92.4Very high80.5Confident3 Ų363 Ų631%0.01330%0.301CS..EExtended strand (participates in β ladder)trans-128.3139.9-173.8-62.3-89.8000113.4R457 I550 Y551 Y603R457-F555 HydrophobicContact CG-CE2 4.08Å; R457-F555 HydrophobicContact CG-CZ 3.91Å; I550-F555 HydrophobicContact CB-CB 4.41Å; I550-F555 HydrophobicContact CB-CD2 3.95Å; I550-F555 HydrophobicContact CB-CG 4.22Å; I550-F555 HydrophobicContact CG2-CD1 4.43Å; I550-F555 HydrophobicContact CG2-CD2 4.08Å; I550-F555 HydrophobicContact CG2-CE2 4.37Å; I550-F555 HydrophobicContact CG2-CG 4.11Å; Y551-F555 PolarHBondContact O-N 3.19Å; F555-Y603 CarbonylContact C-O 3.56Å; F555-Y603 VanDerWaalsContact CA-O 3.28Å; F555-Y603 WeakPolarHBondContact CA-O 3.35Å
556I93Very high79.9Confident14 Ų1458 Ų587%0.07228%0.279CS..EExtended strand (participates in β ladder)trans-96.9143.8159-67.1156.2000107.6I487 L575 Y586 T602 Y603 N605I487-I556 HydrophobicContact CD1-CD1 4Å; I487-I556 HydrophobicContact CD1-CG1 4.43Å; I487-I556 HydrophobicContact CD1-CG2 4.1Å; I556-L575 HydrophobicContact CG2-CD2 3.78Å; I556-Y586 VanDerWaalsContact CD1-C 3.41Å; I556-Y586 WeakPolarHBondContact CD1-O 3.23Å; I556-T602 CarbonylContact O-C 3.54Å; I556-T602 WeakPolarHBondContact O-CA 3.07Å; I556-Y603 PolarHBondContact N-O 2.95Å; I556-Y603 PolarHBondContact O-N 2.92Å; I556-N605 HydrophobicContact CD1-CB 4.2Å; I556-N605 HydrophobicContact CG1-CB 3.99Å
557C91.5Very high79.3Confident3 Ų357 Ų572%0.0227%0.274CS..EExtended strand (participates in β ladder)trans-117142.8171.8-175.80000111A537 C542 D601A537-C557 HydrophobicContact CB-CB 4.45Å; A537-C557 PolarHBondContact N-O 3.14Å; C542-C557 HydrophobicContact CB-CB 3.57Å; C542-C557 WeakPolarHBondContact CB-SG 3.29Å; C542-C557 WeakPolarHBondContact SG-CB 3.07Å; C542-C557 CovalentContact SG-SG 2.01Å; C542-C557 PolarHBondContact SG-SG 3.38Å; C557-D601 WeakPolarHBondContact CA-O 3.32Å
558T90Very high78.7Confident1 Ų150.9 Ų50.91%0.00625%0.247CC..EExtended strand (participates in β ladder)trans-125142.7171.3670000110.6V534 S535 L575 F600 D601 Y603V534-T558 HydrophobicContact CB-CG2 4.37Å; V534-T558 HydrophobicContact CG2-CG2 3.67Å; S535-T558 CarbonylContact O-C 3.57Å; S535-T558 WeakPolarHBondContact O-CA 3.24Å; S535-T558 WeakPolarHBondContact O-CB 3.5Å; T558-L575 HydrophobicContact CG2-CD1 3.97Å; T558-L575 HydrophobicContact CG2-CD2 3.77Å; T558-F600 WeakPolarHBondContact O-CA 3.08Å; T558-D601 PolarHBondContact N-O 3.49Å; T558-D601 PolarHBondContact O-N 2.92Å; T558-Y603 HydrophobicContact CG2-CD2 4.19Å; T558-Y603 HydrophobicContact CG2-CE2 3.62Å; T558-Y603 VanDerWaalsContact OG1-CE2 3.28Å; T558-Y603 WeakPolarHBondContact OG1-CE2 3.29Å; T558-Y603 PolarHBondContact OG1-OH 3.23Å
559Q83.7Confident78.2Confident77 Ų7750.2 Ų50.236%0.3625%0.25SC..EExtended strand (participates in β ladder)trans-93.6147.6167.3-164.8174.817.900109.1S535 A537 E599 F600S535-Q559 PolarHBondContact N-O 2.81Å; S535-Q559 PolarHBondContact O-N 2.98Å; A537-Q559 HydrophobicContact CB-CB 4.07Å; Q559-E599 CarbonylContact C-O 3.59Å; Q559-E599 VanDerWaalsContact CA-O 3.27Å; Q559-E599 WeakPolarHBondContact CA-O 3.42Å; Q559-E599 HydrophobicContact CG-CG 4.21Å; Q559-E599 PolarHBondContact NE2-OE1 3.1Å; Q559-F600 HydrophobicContact CB-CD1 3.97Å; Q559-F600 HydrophobicContact CB-CE1 3.69Å; Q559-F600 HydrophobicContact CB-CZ 4.49Å; Q559-F600 HydrophobicContact CG-CD1 4.05Å; Q559-F600 HydrophobicContact CG-CE1 3.55Å; Q559-F600 HydrophobicContact CG-CZ 3.86Å
560S69.4Low78Confident11 Ų1147 Ų478%0.07722%0.222CC..  trans-120.3131-179.284.20000111.9R564 K598 E599S560-R564 WeakPolarHBondContact CB-O 3.22Å; S560-R564 PolarHBondContact OG-N 2.89Å; S560-R564 VanDerWaalsContact OG-N 3.15Å; S560-R564 PolarHBondContact OG-O 2.97Å; S560-K598 PolarHBondContact OG-O 2.71Å; S560-E599 PolarHBondContact N-O 2.74Å
561E61.3Low78Confident133 Ų13347.4 Ų47.462%0.62123%0.226SC*.G310 helixtrans-77.5145.5161.9-62.7-166.1154.600109.6H563 R564E561-H563 PolarHBondContact O-N 2.73Å; E561-R564 WeakPolarHBondContact O-CB 3.24Å; E561-R564 WeakPolarHBondContact O-CD 3.22Å; E561-R564 WeakPolarHBondContact O-CG 3.49Å; E561-R564 PolarHBondContact O-N 3.29Å; E561-R564 VanDerWaalsContact O-N 3.16Å
562F59.1Low78.1Confident158 Ų15842.3 Ų42.369%0.69321%0.206SC*.G310 helixtrans55.532.6175.9-48.7-78.7000115R564F562-R564 VanDerWaalsContact C-N 3.26Å; F562-R564 PolarHBondContact O-N 2.87Å
563H62.4Low78.2Confident118 Ų11837.7 Ų37.755%0.54618%0.184SC..G310 helixtrans58.737.9-178.5-61.5-69.7000112.7S354 E561 G597S354-H563 WeakPolarHBondContact CB-O 3.28Å; S354-H563 PolarHBondContact OG-O 2.87Å; E561-H563 PolarHBondContact O-N 2.73Å; H563-G597 VanDerWaalsContact CB-O 3.27Å; H563-G597 WeakPolarHBondContact CB-O 3.21Å; H563-G597 PolarHBondContact ND1-O 3.47Å; H563-G597 WeakPolarHBondContact O-CA 3.43Å
564R64.6Low78.5Confident47 Ų4732.8 Ų32.818%0.17716%0.158CC..  trans-68.6148.2174.1-79.2171.2179.2152.25.9111.4S354 G355 T532 I533 S560 E561 F562S354-R564 WeakPolarHBondContact O-CA 3.45Å; G355-R564 WeakPolarHBondContact O-CG 3.34Å; G355-R564 PolarHBondContact O-NE 2.86Å; T532-R564 WeakPolarHBondContact OG1-CD 3.39Å; T532-R564 WeakPolarHBondContact OG1-CG 3.44Å; I533-R564 WeakPolarHBondContact O-CD 2.95Å; S560-R564 WeakPolarHBondContact CB-O 3.22Å; S560-R564 PolarHBondContact OG-N 2.89Å; S560-R564 VanDerWaalsContact OG-N 3.15Å; S560-R564 PolarHBondContact OG-O 2.97Å; E561-R564 WeakPolarHBondContact O-CB 3.24Å; E561-R564 WeakPolarHBondContact O-CD 3.22Å; E561-R564 WeakPolarHBondContact O-CG 3.49Å; E561-R564 PolarHBondContact O-N 3.29Å; E561-R564 VanDerWaalsContact O-N 3.16Å; F562-R564 VanDerWaalsContact C-N 3.26Å; F562-R564 PolarHBondContact O-N 2.87Å
565G66.5Low78.7Confident0 Ų032.3 Ų32.30%016%0.155CC..BIsolated β-bridgetrans144.8176.5176.800000114.2I353 S354 D601I353-G565 WeakPolarHBondContact CG2-O 3.48Å; S354-G565 VanDerWaalsContact CB-O 3.24Å; S354-G565 WeakPolarHBondContact CB-O 3.16Å; S354-G565 PolarHBondContact N-O 3.4Å; S354-G565 PolarHBondContact O-N 2.85Å; G565-D601 WeakPolarHBondContact CA-OD2 3.2Å
566F73.3Confident78.9Confident8 Ų832.2 Ų32.24%0.03516%0.155CC..  trans-80170-172.162.7-97.7000113.1V495 D570 I589 V592 D601 Y603V495-F566 HydrophobicContact CG1-CB 4.13Å; F566-D570 WeakPolarHBondContact CA-OD2 2.95Å; F566-D570 HydrophobicContact CB-CB 3.84Å; F566-I589 HydrophobicContact CB-CD1 4.08Å; F566-I589 HydrophobicContact CB-CG2 4.16Å; F566-I589 HydrophobicContact CD1-CG1 4.13Å; F566-I589 HydrophobicContact CD1-CG2 3.94Å; F566-I589 HydrophobicContact CD2-CG2 3.35Å; F566-I589 HydrophobicContact CE1-CG2 4.1Å; F566-I589 HydrophobicContact CE2-CG2 3.56Å; F566-I589 HydrophobicContact CG-CD1 4.37Å; F566-I589 HydrophobicContact CG-CG1 4.3Å; F566-I589 HydrophobicContact CG-CG2 3.56Å; F566-I589 HydrophobicContact CZ-CG2 3.94Å; F566-V592 HydrophobicContact CD2-CG2 3.61Å; F566-V592 HydrophobicContact CE2-CG2 3.63Å; F566-D601 HydrophobicContact CD1-CB 4.33Å; F566-D601 HydrophobicContact CE1-CB 3.74Å; F566-D601 HydrophobicContact CZ-CB 4.36Å; F566-Y603 AromaticContact CD1-CE1 3.64Å; F566-Y603 HydrophobicContact CD1-CE1 3.64Å; F566-Y603 AromaticContact CD1-CZ 3.79Å; F566-Y603 HydrophobicContact CE1-CD1 4.13Å; F566-Y603 AromaticContact CE1-CE1 3.55Å; F566-Y603 HydrophobicContact CE1-CE1 3.55Å; F566-Y603 HydrophobicContact CE1-CE2 4.24Å; F566-Y603 AromaticContact CE1-CZ 3.6Å
567C69.9Low79Confident1 Ų131.6 Ų31.61%0.00715%0.152CC..  trans-143.8-170179-161.10000111.6Y500 D570 V592 C596Y500-C567 WeakPolarHBondContact O-CB 3.33Å; Y500-C567 PolarHBondContact O-SG 2.95Å; Y500-C567 VanDerWaalsContact O-SG 3.33Å; C567-D570 PolarHBondContact N-OD2 2.04Å; C567-D570 WeakPolarHBondContact O-CB 3.17Å; C567-D570 PolarHBondContact O-N 2.93Å; C567-V592 VanDerWaalsContact C-CG2 3.46Å; C567-V592 WeakPolarHBondContact O-CG2 3.24Å; C567-C596 WeakPolarHBondContact CA-SG 3.02Å; C567-C596 HydrophobicContact CB-CB 3.55Å; C567-C596 WeakPolarHBondContact CB-SG 3.43Å; C567-C596 WeakPolarHBondContact SG-CB 3.49Å; C567-C596 CovalentContact SG-SG 2.03Å; C567-C596 PolarHBondContact SG-SG 3.3Å
568D65.8Low79.1Confident46 Ų4637.4 Ų37.425%0.24618%0.177CC..THydrogen-bonded Turntrans-56.3143175.2-69.3-31.1000110.6G499 Y500 R503 D570G499-D568 CarbonylContact C-O 3.52Å; G499-D568 WeakPolarHBondContact CA-O 3.46Å; Y500-D568 HydrophobicContact CD2-CB 3.79Å; Y500-D568 WeakPolarHBondContact CD2-O 3.39Å; Y500-D568 PolarHBondContact N-O 3.13Å; R503-D568 WeakPolarHBondContact CD-OD2 3.03Å; R503-D568 WeakPolarHBondContact CG-OD2 3.28Å; R503-D568 IonicContact CZ-OD1 3.03Å; R503-D568 VanDerWaalsContact CZ-OD1 3.24Å; R503-D568 IonicContact CZ-OD2 2.68Å; R503-D568 VanDerWaalsContact NE-CG 3.28Å; R503-D568 IonicContact NE-OD1 2.97Å; R503-D568 PolarHBondContact NE-OD1 2.97Å; R503-D568 VanDerWaalsContact NE-OD1 3.09Å; R503-D568 IonicContact NE-OD2 2.71Å; R503-D568 PolarHBondContact NE-OD2 3.01Å; R503-D568 IonicContact NH2-OD1 2.63Å; R503-D568 PolarHBondContact NH2-OD1 2.88Å; R503-D568 IonicContact NH2-OD2 2.77Å; D568-D570 PolarHBondContact O-N 2.78Å
569S70.2Confident79.3Confident40 Ų4038.7 Ų38.728%0.2819%0.186SC..THydrogen-bonded Turntrans67.42.7-174.3-66.50000116.9
570D80.1Confident79.6Confident3 Ų342.8 Ų42.82%0.01621%0.211CC..  trans-84-12.5161.3-68.8-45.6000113G497 W498 G499 F566 C567 D568 G572 G573 I589G497-D570 WeakPolarHBondContact CA-OD1 3.45Å; W498-D570 PolarHBondContact N-OD1 3.06Å; G499-D570 VanDerWaalsContact CA-OD1 3.27Å; G499-D570 WeakPolarHBondContact CA-OD1 3.29Å; G499-D570 PolarHBondContact N-OD1 3.16Å; F566-D570 WeakPolarHBondContact CA-OD2 2.95Å; F566-D570 HydrophobicContact CB-CB 3.84Å; C567-D570 PolarHBondContact N-OD2 2.04Å; C567-D570 WeakPolarHBondContact O-CB 3.17Å; C567-D570 PolarHBondContact O-N 2.93Å; D568-D570 PolarHBondContact O-N 2.78Å; D570-G572 PolarHBondContact O-N 3.34Å; D570-G573 WeakPolarHBondContact O-CA 3.47Å; D570-G573 PolarHBondContact O-N 3.09Å; D570-I589 HydrophobicContact CB-CD1 4.08Å; D570-I589 HydrophobicContact CB-CG2 4.45Å; D570-I589 WeakPolarHBondContact O-CD1 3.46Å
571T87.2Confident80.5Confident14 Ų1445 Ų459%0.08624%0.235CC..THydrogen-bonded Turntrans-49.6136.5-178.8-54.80000111.9C384 G385 A403 S405 C406 G573C384-T571 CarbonylContact C-O 3.53Å; C384-T571 WeakPolarHBondContact CA-O 3.09Å; C384-T571 WeakPolarHBondContact CB-O 3.45Å; C384-T571 PolarHBondContact SG-O 3.34Å; C384-T571 VanDerWaalsContact SG-O 3.38Å; G385-T571 PolarHBondContact N-O 3.2Å; A403-T571 HydrophobicContact CB-CG2 3.82Å; S405-T571 VanDerWaalsContact OG-CG2 3.32Å; S405-T571 WeakPolarHBondContact OG-CG2 3.21Å; C406-T571 PolarHBondContact SG-O 3.14Å; T571-G573 VanDerWaalsContact C-N 3.27Å; T571-G573 PolarHBondContact O-N 3.18Å
572G90.5Very high82.1Confident0 Ų041.7 Ų41.70%022%0.218CC..THydrogen-bonded Turntrans84.5-16.5-171.600000115.2G385 G386 T402 D570 I589G385-G572 VanDerWaalsContact C-C 3.42Å; G385-G572 CarbonylContact C-O 3.54Å; G385-G572 CarbonylContact O-C 3.31Å; G385-G572 WeakPolarHBondContact O-CA 3.35Å; G386-G572 WeakPolarHBondContact CA-O 3.07Å; T402-G572 WeakPolarHBondContact OG1-CA 3.32Å; D570-G572 PolarHBondContact O-N 3.34Å; G572-I589 PolarHBondContact N-O 2.74Å
573G91.9Very high83.9Confident0 Ų034.9 Ų34.90%019%0.188CC..  trans-64.4163.6173.600000113.2D570 T571 I589D570-G573 WeakPolarHBondContact O-CA 3.47Å; D570-G573 PolarHBondContact O-N 3.09Å; T571-G573 VanDerWaalsContact C-N 3.27Å; T571-G573 PolarHBondContact O-N 3.18Å; G573-I589 WeakPolarHBondContact O-CB 3.24Å; G573-I589 VanDerWaalsContact O-CG1 3.25Å; G573-I589 WeakPolarHBondContact O-CG1 3.21Å; G573-I589 PolarHBondContact O-N 2.96Å
574P95.6Very high85.6Confident1 Ų129.8 Ų29.81%0.00617%0.165CC..EExtended strand (participates in β ladder)trans-94.9155-173.538.6-37.3000113.6M367 T387 V576 Q585M367-P574 HydrophobicContact CE-CG 4.45Å; M367-P574 WeakPolarHBondContact SD-CD 3.38Å; M367-P574 HydrophobicContact SD-CG 3.51Å; M367-P574 VanDerWaalsContact SD-CG 3.51Å; T387-P574 HydrophobicContact CG2-CB 3.67Å; T387-P574 HydrophobicContact CG2-CG 3.6Å; P574-V576 HydrophobicContact CB-CG1 3.74Å; P574-V576 HydrophobicContact CG-CG1 3.97Å; P574-Q585 HydrophobicContact CB-CG 3.72Å
575L94.7Very high87.1Confident0 Ų027.6 Ų27.60%016%0.157CC..EExtended strand (participates in β ladder)trans-101.1107.7152.9177.174.4000107.2C493 I494 V495 V534 I556 T558 Y586 G587 Y603C493-L575 HydrophobicContact CB-CD1 3.54Å; C493-L575 HydrophobicContact CB-CG 4.04Å; I494-L575 WeakPolarHBondContact O-CA 3.38Å; V495-L575 HydrophobicContact CG2-CD1 3.52Å; V534-L575 HydrophobicContact CG2-CD1 3.58Å; I556-L575 HydrophobicContact CG2-CD2 3.78Å; T558-L575 HydrophobicContact CG2-CD1 3.97Å; T558-L575 HydrophobicContact CG2-CD2 3.77Å; L575-Y586 PolarHBondContact O-N 2.87Å; L575-Y586 VanDerWaalsContact O-N 3.14Å; L575-G587 PolarHBondContact N-O 3.19Å; L575-G587 PolarHBondContact O-N 2.8Å; L575-Y603 HydrophobicContact CB-CD1 3.75Å; L575-Y603 HydrophobicContact CB-CE1 3.98Å; L575-Y603 HydrophobicContact CB-CG 4.16Å; L575-Y603 HydrophobicContact CD1-CE1 4.26Å; L575-Y603 HydrophobicContact CD1-CE2 4.49Å; L575-Y603 HydrophobicContact CD2-CD1 4.4Å; L575-Y603 HydrophobicContact CD2-CD2 3.91Å; L575-Y603 HydrophobicContact CD2-CE2 4.23Å; L575-Y603 HydrophobicContact CD2-CG 4.04Å
576V96.2Very high88.6Confident2 Ų227.9 Ų27.91%0.01216%0.158CC..EExtended strand (participates in β ladder)trans-106.9128.9179.8-55.70000111.4I478 C493 I494 P574 W583 V584 Q585I478-V576 HydrophobicContact CD1-CB 4.32Å; I478-V576 HydrophobicContact CD1-CG1 3.82Å; I478-V576 HydrophobicContact CG1-CG1 3.91Å; C493-V576 CarbonylContact C-O 3.57Å; C493-V576 VanDerWaalsContact CA-O 3.32Å; C493-V576 WeakPolarHBondContact CA-O 3.39Å; C493-V576 WeakPolarHBondContact CB-O 3.24Å; I494-V576 HydrophobicContact CB-CG2 3.75Å; I494-V576 HydrophobicContact CD1-CG2 4.4Å; I494-V576 HydrophobicContact CG2-CG2 4.39Å; I494-V576 PolarHBondContact N-O 3.03Å; I494-V576 PolarHBondContact O-N 3.18Å; P574-V576 HydrophobicContact CB-CG1 3.74Å; P574-V576 HydrophobicContact CG-CG1 3.97Å; V576-W583 HydrophobicContact CB-CE3 4.31Å; V576-W583 HydrophobicContact CG2-CE3 3.88Å; V576-W583 HydrophobicContact CG2-CZ3 4.38Å; V576-V584 CarbonylContact C-O 3.5Å; V576-V584 VanDerWaalsContact CA-O 3.29Å; V576-V584 WeakPolarHBondContact CA-O 3.44Å; V576-Q585 HydrophobicContact CG1-CB 4.17Å
577C95.3Very high89.6Confident1 Ų127.5 Ų27.51%0.00716%0.157CC..EExtended strand (participates in β ladder)trans-118.5152.8177.4-44.10000108.9T491 C493 V584 Y586T491-C577 HydrophobicContact CG2-CB 4.17Å; C493-C577 HydrophobicContact CB-CB 4.03Å; C493-C577 WeakPolarHBondContact CB-SG 3.29Å; C493-C577 WeakPolarHBondContact SG-CB 3.49Å; C493-C577 CovalentContact SG-SG 2.04Å; C493-C577 PolarHBondContact SG-SG 2.62Å; C577-V584 PolarHBondContact N-O 3.13Å; C577-V584 PolarHBondContact O-N 3.26Å; C577-Y586 HydrophobicContact CB-CD2 3.71Å; C577-Y586 HydrophobicContact CB-CE2 3.87Å
578K93.6Very high90.8Very high125 Ų12527.5 Ų27.554%0.54316%0.156SC..EExtended strand (participates in β ladder)trans-88.5120.6179.6-162.2175.3-175.7-179.80110.2G581 K582 W583K578-G581 VanDerWaalsContact CE-O 3.29Å; K578-G581 WeakPolarHBondContact CE-O 3.22Å; K578-K582 CarbonylContact C-O 3.54Å; K578-K582 WeakPolarHBondContact CA-O 3.35Å; K578-W583 HydrophobicContact CB-CD2 4.36Å; K578-W583 HydrophobicContact CB-CE3 4.12Å; K578-W583 HydrophobicContact CB-CH2 4.18Å; K578-W583 HydrophobicContact CB-CZ2 4.42Å; K578-W583 HydrophobicContact CB-CZ3 4.03Å; K578-W583 HydrophobicContact CD-CZ2 4.22Å
579S93.3Very high92Very high28 Ų2825.3 Ų25.320%0.19614%0.144CC..EExtended strand (participates in β ladder)trans-131.8130.4178.5-177.30000109.8G581 K582 Y586S579-G581 PolarHBondContact O-N 3.07Å; S579-G581 VanDerWaalsContact O-N 3.08Å; S579-K582 PolarHBondContact N-O 2.88Å; S579-K582 PolarHBondContact O-N 3.31Å; S579-Y586 WeakPolarHBondContact CB-OH 3.25Å; S579-Y586 PolarHBondContact OG-OH 2.64Å
580N90.1Very high92.7Very high163 Ų16323.5 Ų23.587%0.87213%0.132SC*.THydrogen-bonded Turntrans47.340.5-179-61.9-37.9000114.2K582N580-K582 VanDerWaalsContact C-N 3.28Å; N580-K582 PolarHBondContact O-N 2.97Å
581G89.2Confident92.2Very high57 Ų5726.5 Ų26.559%0.58815%0.15SC*.THydrogen-bonded Turntrans84-17.1-179.500000115.8K578 S579K578-G581 VanDerWaalsContact CE-O 3.29Å; K578-G581 WeakPolarHBondContact CE-O 3.22Å; S579-G581 PolarHBondContact O-N 3.07Å; S579-G581 VanDerWaalsContact O-N 3.08Å
582K94.2Very high91Very high63 Ų6326.3 Ų26.327%0.27415%0.149SC..EExtended strand (participates in β ladder)trans-102.6155.2-177.5-60-174.6176.6-178.80111.7E333 V336 K578 S579 N580E333-K582 IonicContact OE1-NZ 3.1Å; E333-K582 PolarHBondContact OE1-NZ 2.83Å; E333-K582 WeakPolarHBondContact OE2-CE 3.27Å; E333-K582 IonicContact OE2-NZ 3.17Å; E333-K582 PolarHBondContact OE2-NZ 2.93Å; V336-K582 HydrophobicContact CG2-CD 4.33Å; V336-K582 HydrophobicContact CG2-CG 3.97Å; K578-K582 CarbonylContact C-O 3.54Å; K578-K582 WeakPolarHBondContact CA-O 3.35Å; S579-K582 PolarHBondContact N-O 2.88Å; S579-K582 PolarHBondContact O-N 3.31Å; N580-K582 VanDerWaalsContact C-N 3.28Å; N580-K582 PolarHBondContact O-N 2.97Å
583W96.5Very high89.5Confident16 Ų1629.3 Ų29.36%0.06117%0.168CC..EExtended strand (participates in β ladder)trans-86.5128.8172.1-67.595.8000110.7G335 I343 M345 W366 I478 C479 I494 V576 K578G335-W583 VanDerWaalsContact CA-O 3.31Å; G335-W583 WeakPolarHBondContact CA-O 3.19Å; G335-W583 PolarHBondContact O-N 2.92Å; I343-W583 HydrophobicContact CB-CZ2 4.45Å; I343-W583 HydrophobicContact CD1-CD2 4.36Å; I343-W583 HydrophobicContact CD1-CG 4.4Å; I343-W583 HydrophobicContact CD1-CZ2 4.33Å; I343-W583 HydrophobicContact CG2-CZ2 4.02Å; M345-W583 HydrophobicContact CE-CH2 3.97Å; M345-W583 HydrophobicContact CG-CH2 4.45Å; M345-W583 HydrophobicContact SD-CH2 3.67Å; M345-W583 HydrophobicContact SD-CZ2 4.32Å; W366-W583 HydrophobicContact CH2-CB 3.79Å; W366-W583 AromaticContact CH2-CD1 3.75Å; W366-W583 AromaticContact CH2-CG 3.82Å; W366-W583 HydrophobicContact CH2-CG 3.82Å; W366-W583 HydrophobicContact CZ2-CB 4.1Å; W366-W583 HydrophobicContact CZ2-CG 4.2Å; W366-W583 HydrophobicContact CZ3-CB 4.46Å; I478-W583 HydrophobicContact CD1-CB 3.58Å; I478-W583 WeakPolarHBondContact CD1-O 3.43Å; C479-W583 WeakPolarHBondContact CB-O 3.28Å; C479-W583 PolarHBondContact N-O 3.11Å; I494-W583 HydrophobicContact CD1-CE3 4.2Å; I494-W583 HydrophobicContact CD1-CH2 3.41Å; I494-W583 VanDerWaalsContact CD1-CH2 3.41Å; I494-W583 HydrophobicContact CD1-CZ2 3.97Å; I494-W583 HydrophobicContact CD1-CZ3 3.54Å; I494-W583 HydrophobicContact CG1-CH2 4.02Å; I494-W583 HydrophobicContact CG1-CZ3 3.92Å; V576-W583 HydrophobicContact CB-CE3 4.31Å; V576-W583 HydrophobicContact CG2-CE3 3.88Å; V576-W583 HydrophobicContact CG2-CZ3 4.38Å; K578-W583 HydrophobicContact CB-CD2 4.36Å; K578-W583 HydrophobicContact CB-CE3 4.12Å; K578-W583 HydrophobicContact CB-CH2 4.18Å; K578-W583 HydrophobicContact CB-CZ2 4.42Å; K578-W583 HydrophobicContact CB-CZ3 4.03Å; K578-W583 HydrophobicContact CD-CZ2 4.22Å
584V97.9Very high87.9Confident11 Ų1131 Ų317%0.06718%0.184CC..EExtended strand (participates in β ladder)trans-124.6129.4-175.8-1780000109.3C479 P481 V576 C577 Y586C479-V584 HydrophobicContact CB-CG2 4.03Å; C479-V584 WeakPolarHBondContact O-CA 3.21Å; P481-V584 HydrophobicContact CB-CG1 3.86Å; P481-V584 HydrophobicContact CG-CG1 4.38Å; V576-V584 CarbonylContact C-O 3.5Å; V576-V584 VanDerWaalsContact CA-O 3.29Å; V576-V584 WeakPolarHBondContact CA-O 3.44Å; C577-V584 PolarHBondContact N-O 3.13Å; C577-V584 PolarHBondContact O-N 3.26Å; V584-Y586 HydrophobicContact CB-CD2 4.07Å; V584-Y586 HydrophobicContact CB-CE2 3.61Å; V584-Y586 HydrophobicContact CG1-CD2 4Å; V584-Y586 HydrophobicContact CG1-CE1 4.28Å; V584-Y586 HydrophobicContact CG1-CE2 3.7Å; V584-Y586 HydrophobicContact CG1-CG 4.42Å; V584-Y586 HydrophobicContact CG2-CE2 4.5Å; V584-Y586 WeakPolarHBondContact O-CD2 3.23Å; V584-Y586 PolarHBondContact O-N 2.9Å
585Q97.7Very high86.4Confident0 Ų040.9 Ų40.90%022%0.222CC..EExtended strand (participates in β ladder)trans-82.695.1174.9-178.1178.3-6.300110.5T387 I478 C479 P481 P574 V576 G587 V606T387-Q585 PolarHBondContact OG1-OE1 2.82Å; I478-Q585 HydrophobicContact CG1-CB 3.86Å; I478-Q585 HydrophobicContact CG2-CB 4.01Å; C479-Q585 PolarHBondContact O-N 2.89Å; P481-Q585 WeakPolarHBondContact CD-O 3.27Å; P574-Q585 HydrophobicContact CB-CG 3.72Å; V576-Q585 HydrophobicContact CG1-CB 4.17Å; Q585-G587 VanDerWaalsContact CG-O 3.24Å; Q585-G587 WeakPolarHBondContact CG-O 3.34Å; Q585-G587 PolarHBondContact NE2-O 2.85Å; Q585-V606 HydrophobicContact CG-CG2 4.36Å
586Y97.4Very high85.1Confident7 Ų742 Ų423%0.02723%0.229CC..EExtended strand (participates in β ladder)trans-83.5-35.3175.2-69.5-87.3000112.8P481 E485 I487 I556 L575 C577 S579 V584 V606P481-Y586 HydrophobicContact CB-CD1 3.73Å; P481-Y586 HydrophobicContact CB-CE1 3.69Å; P481-Y586 HydrophobicContact CG-CD1 4.17Å; E485-Y586 HydrophobicContact CB-CE1 4.25Å; E485-Y586 HydrophobicContact CG-CE1 3.93Å; E485-Y586 PolarHBondContact OE1-OH 3.14Å; I487-Y586 HydrophobicContact CD1-CD1 4.23Å; I487-Y586 HydrophobicContact CD1-CD2 4.18Å; I487-Y586 HydrophobicContact CD1-CG 3.76Å; I487-Y586 HydrophobicContact CG1-CD1 3.57Å; I487-Y586 HydrophobicContact CG1-CD2 3.96Å; I487-Y586 HydrophobicContact CG1-CE1 4.01Å; I487-Y586 HydrophobicContact CG1-CE2 4.33Å; I487-Y586 HydrophobicContact CG1-CG 3.55Å; I556-Y586 VanDerWaalsContact CD1-C 3.41Å; I556-Y586 WeakPolarHBondContact CD1-O 3.23Å; L575-Y586 PolarHBondContact O-N 2.87Å; L575-Y586 VanDerWaalsContact O-N 3.14Å; C577-Y586 HydrophobicContact CB-CD2 3.71Å; C577-Y586 HydrophobicContact CB-CE2 3.87Å; S579-Y586 WeakPolarHBondContact CB-OH 3.25Å; S579-Y586 PolarHBondContact OG-OH 2.64Å; V584-Y586 HydrophobicContact CB-CD2 4.07Å; V584-Y586 HydrophobicContact CB-CE2 3.61Å; V584-Y586 HydrophobicContact CG1-CD2 4Å; V584-Y586 HydrophobicContact CG1-CE1 4.28Å; V584-Y586 HydrophobicContact CG1-CE2 3.7Å; V584-Y586 HydrophobicContact CG1-CG 4.42Å; V584-Y586 HydrophobicContact CG2-CE2 4.5Å; V584-Y586 WeakPolarHBondContact O-CD2 3.23Å; V584-Y586 PolarHBondContact O-N 2.9Å; Y586-V606 VanDerWaalsContact O-CB 3.25Å; Y586-V606 WeakPolarHBondContact O-CB 3.41Å; Y586-V606 WeakPolarHBondContact O-CG2 3.25Å; Y586-V606 PolarHBondContact O-N 3.23Å
587G95.4Very high83.5Confident0 Ų042.4 Ų42.40%023%0.233CC..EExtended strand (participates in β ladder)trans-118.6161.4-178.500000113.3L575 Q585 T604L575-G587 PolarHBondContact N-O 3.19Å; L575-G587 PolarHBondContact O-N 2.8Å; Q585-G587 VanDerWaalsContact CG-O 3.24Å; Q585-G587 WeakPolarHBondContact CG-O 3.34Å; Q585-G587 PolarHBondContact NE2-O 2.85Å; G587-T604 WeakPolarHBondContact CA-O 3.16Å
588L94.6Very high82.2Confident0 Ų044.4 Ų44.40%024%0.242CC..EExtended strand (participates in β ladder)trans-134.3132.4174.4-174.6146.9000110L401 T402 A403 I460 S590 Y603 T604 V606L401-L588 HydrophobicContact CD2-CD1 4.16Å; L401-L588 HydrophobicContact CG-CD1 3.85Å; T402-L588 WeakPolarHBondContact O-CD1 3.35Å; A403-L588 HydrophobicContact CB-CD2 3.8Å; I460-L588 HydrophobicContact CG1-CD1 4.43Å; L588-S590 PolarHBondContact O-N 2.79Å; L588-Y603 CarbonylContact O-C 3.54Å; L588-Y603 VanDerWaalsContact O-CA 3.29Å; L588-Y603 WeakPolarHBondContact O-CA 3.4Å; L588-Y603 WeakPolarHBondContact O-CB 3.29Å; L588-T604 PolarHBondContact N-O 3.49Å; L588-T604 PolarHBondContact O-N 2.74Å; L588-V606 HydrophobicContact CB-CG2 4.03Å
589I90.6Very high81.4Confident0 Ų043 Ų430%024%0.238CC..EExtended strand (participates in β ladder)trans-70.7111.9-175.6-60.5167.2000109.2V495 F566 D570 G572 G573 Y603V495-I589 HydrophobicContact CG1-CD1 3.63Å; V495-I589 HydrophobicContact CG1-CG1 4.32Å; F566-I589 HydrophobicContact CB-CD1 4.08Å; F566-I589 HydrophobicContact CB-CG2 4.16Å; F566-I589 HydrophobicContact CD1-CG1 4.13Å; F566-I589 HydrophobicContact CD1-CG2 3.94Å; F566-I589 HydrophobicContact CD2-CG2 3.35Å; F566-I589 HydrophobicContact CE1-CG2 4.1Å; F566-I589 HydrophobicContact CE2-CG2 3.56Å; F566-I589 HydrophobicContact CG-CD1 4.37Å; F566-I589 HydrophobicContact CG-CG1 4.3Å; F566-I589 HydrophobicContact CG-CG2 3.56Å; F566-I589 HydrophobicContact CZ-CG2 3.94Å; D570-I589 HydrophobicContact CB-CD1 4.08Å; D570-I589 HydrophobicContact CB-CG2 4.45Å; D570-I589 WeakPolarHBondContact O-CD1 3.46Å; G572-I589 PolarHBondContact N-O 2.74Å; G573-I589 WeakPolarHBondContact O-CB 3.24Å; G573-I589 VanDerWaalsContact O-CG1 3.25Å; G573-I589 WeakPolarHBondContact O-CG1 3.21Å; G573-I589 PolarHBondContact O-N 2.96Å; I589-Y603 HydrophobicContact CG1-CD1 3.89Å; I589-Y603 HydrophobicContact CG1-CE1 3.83Å
590S84.5Confident80.9Confident2 Ų242.2 Ų42.21%0.01423%0.231CC..  trans-83.2-173.9171.9-175.10000111T456 D459 L588T456-S590 WeakPolarHBondContact CB-OG 3.34Å; D459-S590 VanDerWaalsContact CB-OG 3.3Å; D459-S590 WeakPolarHBondContact CB-OG 3.42Å; D459-S590 WeakPolarHBondContact OD2-CA 3.48Å; D459-S590 WeakPolarHBondContact OD2-CB 3.34Å; D459-S590 PolarHBondContact OD2-OG 2.84Å; L588-S590 PolarHBondContact O-N 2.79Å
591T70.2Confident80.7Confident66 Ų6635 Ų3541%0.40519%0.192SC..  trans-63.6134.1178.4-650000111.9S405 D459 V593S405-T591 WeakPolarHBondContact CB-OG1 3.31Å; S405-T591 PolarHBondContact OG-OG1 2.7Å; D459-T591 PolarHBondContact OD2-N 3.4Å; T591-V593 PolarHBondContact O-N 2.88Å; T591-V593 VanDerWaalsContact O-N 3.13Å
592V62.3Low80.7Confident11 Ų1132.6 Ų32.67%0.06717%0.166CC..  trans-68.6106.9179.1-179.80000111.6R503 F566 C567R503-V592 PolarHBondContact NH1-O 3.08Å; R503-V592 PolarHBondContact NH2-O 3.36Å; F566-V592 HydrophobicContact CD2-CG2 3.61Å; F566-V592 HydrophobicContact CE2-CG2 3.63Å; C567-V592 VanDerWaalsContact C-CG2 3.46Å; C567-V592 WeakPolarHBondContact O-CG2 3.24Å
593V57.3Low80.6Confident63 Ų6329.6 Ų29.638%0.38215%0.153SC..  trans-85.2118.3167.6-175.40000109.2T456 Y548 T591 K598T456-V593 HydrophobicContact CG2-CG2 3.91Å; Y548-V593 HydrophobicContact CD1-CG1 4.3Å; Y548-V593 HydrophobicContact CE1-CB 4.28Å; Y548-V593 HydrophobicContact CE1-CG1 4.29Å; T591-V593 PolarHBondContact O-N 2.88Å; T591-V593 VanDerWaalsContact O-N 3.13Å; V593-K598 VanDerWaalsContact O-CE 3.25Å; V593-K598 WeakPolarHBondContact O-CE 3.27Å; V593-K598 PolarHBondContact O-NZ 3.15Å
594G59.5Low80.5Confident34 Ų3428.9 Ų28.935%0.35115%0.15SC..SBendtrans92.6-142.7175.900000115.4R503R503-G594 WeakPolarHBondContact CD-O 3.32Å; R503-G594 PolarHBondContact NH1-O 3.27Å
595R63.2Low80.4Confident210 Ų21029.2 Ų29.279%0.79215%0.152SC*.  trans-92.4155.3177.1-60.2-178-172.6-174.13.7110.2K598R595-K598 WeakPolarHBondContact O-CG 3.46Å
596C68.6Low80.4Confident23 Ų2329.2 Ų29.216%0.15515%0.152CC..SBendtrans-74.1154.7170.5-47.40000110.5C567C567-C596 WeakPolarHBondContact CA-SG 3.02Å; C567-C596 HydrophobicContact CB-CB 3.55Å; C567-C596 WeakPolarHBondContact CB-SG 3.43Å; C567-C596 WeakPolarHBondContact SG-CB 3.49Å; C567-C596 CovalentContact SG-SG 2.03Å; C567-C596 PolarHBondContact SG-SG 3.3Å
597G62.7Low80.4Confident10 Ų1029 Ų2910%0.10315%0.151CC..SBendtrans70.348.3-177.900000112.9S354 H563S354-G597 WeakPolarHBondContact OG-CA 3.44Å; H563-G597 VanDerWaalsContact CB-O 3.27Å; H563-G597 WeakPolarHBondContact CB-O 3.21Å; H563-G597 PolarHBondContact ND1-O 3.47Å; H563-G597 WeakPolarHBondContact O-CA 3.43Å
598K68.3Low80.4Confident44 Ų4431.5 Ų31.519%0.19117%0.169CC..  trans-72.7160.7170.1-72.1-179.9164.9-170.60110.1S560 V593 R595 F600S560-K598 PolarHBondContact OG-O 2.71Å; V593-K598 VanDerWaalsContact O-CE 3.25Å; V593-K598 WeakPolarHBondContact O-CE 3.27Å; V593-K598 PolarHBondContact O-NZ 3.15Å; R595-K598 WeakPolarHBondContact O-CG 3.46Å; K598-F600 VanDerWaalsContact C-N 3.25Å; K598-F600 VanDerWaalsContact CB-O 3.26Å; K598-F600 WeakPolarHBondContact CB-O 3.47Å
599E75Confident80.5Confident96 Ų9632 Ų3245%0.44917%0.171SC..SBendtrans-65-35.5167.7-170.1-172.2163.800110.9Q559 S560Q559-E599 CarbonylContact C-O 3.59Å; Q559-E599 VanDerWaalsContact CA-O 3.27Å; Q559-E599 WeakPolarHBondContact CA-O 3.42Å; Q559-E599 HydrophobicContact CG-CG 4.21Å; Q559-E599 PolarHBondContact NE2-OE1 3.1Å; S560-E599 PolarHBondContact N-O 2.74Å
600F84.8Confident80.8Confident10 Ų1032.3 Ų32.34%0.04417%0.172CC..EExtended strand (participates in β ladder)trans-126.1130177.6-61.5-82.6000111.3A537 I541 C542 K545 L546 T558 Q559 K598A537-F600 HydrophobicContact CB-CD1 4.11Å; A537-F600 HydrophobicContact CB-CE1 4.07Å; I541-F600 HydrophobicContact CG2-CE1 3.9Å; I541-F600 HydrophobicContact CG2-CE2 4.32Å; I541-F600 HydrophobicContact CG2-CZ 3.56Å; C542-F600 WeakPolarHBondContact SG-CD1 3.22Å; K545-F600 HydrophobicContact CB-CD2 3.83Å; K545-F600 HydrophobicContact CB-CE2 4.02Å; K545-F600 HydrophobicContact CG-CD2 4.09Å; K545-F600 HydrophobicContact CG-CE2 3.73Å; K545-F600 HydrophobicContact CG-CZ 4.42Å; L546-F600 HydrophobicContact CD2-CB 4.44Å; T558-F600 WeakPolarHBondContact O-CA 3.08Å; Q559-F600 HydrophobicContact CB-CD1 3.97Å; Q559-F600 HydrophobicContact CB-CE1 3.69Å; Q559-F600 HydrophobicContact CB-CZ 4.49Å; Q559-F600 HydrophobicContact CG-CD1 4.05Å; Q559-F600 HydrophobicContact CG-CE1 3.55Å; Q559-F600 HydrophobicContact CG-CZ 3.86Å; K598-F600 VanDerWaalsContact C-N 3.25Å; K598-F600 VanDerWaalsContact CB-O 3.26Å; K598-F600 WeakPolarHBondContact CB-O 3.47Å
601D85.4Confident81.4Confident12 Ų1239 Ų396%0.06420%0.203CC..EExtended strand (participates in β ladder)trans-122.4150176.7-82.1-30.3000110.6C557 T558 G565 F566 Y603C557-D601 WeakPolarHBondContact CA-O 3.32Å; T558-D601 PolarHBondContact N-O 3.49Å; T558-D601 PolarHBondContact O-N 2.92Å; G565-D601 WeakPolarHBondContact CA-OD2 3.2Å; F566-D601 HydrophobicContact CD1-CB 4.33Å; F566-D601 HydrophobicContact CE1-CB 3.74Å; F566-D601 HydrophobicContact CZ-CB 4.36Å; D601-Y603 HydrophobicContact CB-CE2 4.08Å
602T89.4Confident82.7Confident7 Ų737 Ų374%0.04319%0.188CC..EExtended strand (participates in β ladder)trans-120.9144.3-177.764.90000112.9L546 Y548 I550 I556L546-T602 HydrophobicContact CD1-CG2 3.38Å; Y548-T602 HydrophobicContact CE2-CG2 4.44Å; Y548-T602 WeakPolarHBondContact OH-CG2 3.46Å; Y548-T602 PolarHBondContact OH-OG1 3.43Å; I550-T602 HydrophobicContact CG2-CG2 4.27Å; I556-T602 CarbonylContact O-C 3.54Å; I556-T602 WeakPolarHBondContact O-CA 3.07Å
603Y92.1Very high84.3Confident0 Ų036.5 Ų36.50%019%0.185CC..EExtended strand (participates in β ladder)trans-131.1145-176.5-51.8-101.3000109.4V495 F555 I556 T558 F566 L575 L588 I589 D601 N605V495-Y603 HydrophobicContact CG1-CE1 4.4Å; V495-Y603 HydrophobicContact CG2-CE1 3.94Å; V495-Y603 WeakPolarHBondContact CG2-OH 3.39Å; F555-Y603 CarbonylContact C-O 3.56Å; F555-Y603 VanDerWaalsContact CA-O 3.28Å; F555-Y603 WeakPolarHBondContact CA-O 3.35Å; I556-Y603 PolarHBondContact N-O 2.95Å; I556-Y603 PolarHBondContact O-N 2.92Å; T558-Y603 HydrophobicContact CG2-CD2 4.19Å; T558-Y603 HydrophobicContact CG2-CE2 3.62Å; T558-Y603 VanDerWaalsContact OG1-CE2 3.28Å; T558-Y603 WeakPolarHBondContact OG1-CE2 3.29Å; T558-Y603 PolarHBondContact OG1-OH 3.23Å; F566-Y603 AromaticContact CD1-CE1 3.64Å; F566-Y603 HydrophobicContact CD1-CE1 3.64Å; F566-Y603 AromaticContact CD1-CZ 3.79Å; F566-Y603 HydrophobicContact CE1-CD1 4.13Å; F566-Y603 AromaticContact CE1-CE1 3.55Å; F566-Y603 HydrophobicContact CE1-CE1 3.55Å; F566-Y603 HydrophobicContact CE1-CE2 4.24Å; F566-Y603 AromaticContact CE1-CZ 3.6Å; L575-Y603 HydrophobicContact CB-CD1 3.75Å; L575-Y603 HydrophobicContact CB-CE1 3.98Å; L575-Y603 HydrophobicContact CB-CG 4.16Å; L575-Y603 HydrophobicContact CD1-CE1 4.26Å; L575-Y603 HydrophobicContact CD1-CE2 4.49Å; L575-Y603 HydrophobicContact CD2-CD1 4.4Å; L575-Y603 HydrophobicContact CD2-CD2 3.91Å; L575-Y603 HydrophobicContact CD2-CE2 4.23Å; L575-Y603 HydrophobicContact CD2-CG 4.04Å; L588-Y603 CarbonylContact O-C 3.54Å; L588-Y603 VanDerWaalsContact O-CA 3.29Å; L588-Y603 WeakPolarHBondContact O-CA 3.4Å; L588-Y603 WeakPolarHBondContact O-CB 3.29Å; I589-Y603 HydrophobicContact CG1-CD1 3.89Å; I589-Y603 HydrophobicContact CG1-CE1 3.83Å; D601-Y603 HydrophobicContact CB-CE2 4.08Å; Y603-N605 PolarHBondContact O-N 3.18Å
604T94Very high86.2Confident1 Ų139.1 Ų39.11%0.00619%0.191CC..EExtended strand (participates in β ladder)trans-60.5125169.9-54.10000109D459 I460 G587 L588 V606 Y609D459-T604 PolarHBondContact O-OG1 3.28Å; D459-T604 VanDerWaalsContact O-OG1 3.09Å; I460-T604 HydrophobicContact CB-CG2 4.28Å; G587-T604 WeakPolarHBondContact CA-O 3.16Å; L588-T604 PolarHBondContact N-O 3.49Å; L588-T604 PolarHBondContact O-N 2.74Å; T604-V606 PolarHBondContact O-N 3.07Å; T604-V606 VanDerWaalsContact O-N 3.16Å; T604-Y609 HydrophobicContact CG2-CD2 3.83Å; T604-Y609 HydrophobicContact CG2-CE2 3.41Å; T604-Y609 VanDerWaalsContact CG2-CE2 3.41Å
605N95.4Very high88Confident17 Ų1743.1 Ų43.19%0.09120%0.201CC..EExtended strand (participates in β ladder)trans-76.798.4-176.4-174.9-4.8000111.5E552 E554 I556 Y603 S607 S608 Y609E552-N605 PolarHBondContact O-ND2 3.45Å; E554-N605 WeakPolarHBondContact O-CB 3.35Å; E554-N605 PolarHBondContact O-N 2.01Å; I556-N605 HydrophobicContact CD1-CB 4.2Å; I556-N605 HydrophobicContact CG1-CB 3.99Å; Y603-N605 PolarHBondContact O-N 3.18Å; N605-S607 VanDerWaalsContact C-N 3.25Å; N605-S607 PolarHBondContact O-N 3.1Å; N605-S607 PolarHBondContact OD1-N 3.25Å; N605-S607 PolarHBondContact OD1-OG 2.74Å; N605-S607 VanDerWaalsContact OD1-OG 3.07Å; N605-S608 PolarHBondContact ND2-OG 2.84Å; N605-S608 WeakPolarHBondContact O-CB 3.43Å; N605-S608 PolarHBondContact O-N 3.44Å; N605-S608 VanDerWaalsContact O-N 3.1Å; N605-Y609 WeakPolarHBondContact O-CD2 3.31Å
606V97.3Very high89.6Confident0 Ų033.1 Ų33.10%016%0.163CC..G310 helixtrans-60.8-31.8-174.6-179.80000112.2L401 L480 P481 Q585 Y586 L588 T604 S608 Y609 I610 I613L401-V606 HydrophobicContact CD2-CG1 4.06Å; L401-V606 HydrophobicContact CD2-CG2 4.37Å; L480-V606 HydrophobicContact CD2-CG1 3.94Å; P481-V606 HydrophobicContact CG-CB 4.46Å; P481-V606 HydrophobicContact CG-CG1 4.35Å; Q585-V606 HydrophobicContact CG-CG2 4.36Å; Y586-V606 VanDerWaalsContact O-CB 3.25Å; Y586-V606 WeakPolarHBondContact O-CB 3.41Å; Y586-V606 WeakPolarHBondContact O-CG2 3.25Å; Y586-V606 PolarHBondContact O-N 3.23Å; L588-V606 HydrophobicContact CB-CG2 4.03Å; T604-V606 PolarHBondContact O-N 3.07Å; T604-V606 VanDerWaalsContact O-N 3.16Å; V606-S608 PolarHBondContact O-N 2.9Å; V606-Y609 PolarHBondContact O-N 2.9Å; V606-I610 HydrophobicContact CG1-CD1 4.15Å; V606-I610 PolarHBondContact O-N 2.81Å; V606-I613 HydrophobicContact CG1-CD1 3.97Å
607S96.9Very high90.8Very high3 Ų332.8 Ų32.82%0.02116%0.16CC..G310 helixtrans-64.9-24.5179.581.50000112.8Q482 P483 G484 E485 N605Q482-S607 WeakPolarHBondContact O-CB 3.14Å; P483-S607 WeakPolarHBondContact CA-O 3.39Å; G484-S607 PolarHBondContact N-O 3.25Å; E485-S607 WeakPolarHBondContact O-CB 3.33Å; E485-S607 PolarHBondContact O-OG 3.06Å; N605-S607 VanDerWaalsContact C-N 3.25Å; N605-S607 PolarHBondContact O-N 3.1Å; N605-S607 PolarHBondContact OD1-N 3.25Å; N605-S607 PolarHBondContact OD1-OG 2.74Å; N605-S607 VanDerWaalsContact OD1-OG 3.07Å
608S96.3Very high92.3Very high53 Ų5336.8 Ų36.837%0.37119%0.186SC..G310 helixtrans-78.6-16.8173.9-54.80000113.9N553 N605 V606N553-S608 WeakPolarHBondContact O-CB 3.4Å; N553-S608 PolarHBondContact O-OG 2.95Å; N605-S608 PolarHBondContact ND2-OG 2.84Å; N605-S608 WeakPolarHBondContact O-CB 3.43Å; N605-S608 PolarHBondContact O-N 3.44Å; N605-S608 VanDerWaalsContact O-N 3.1Å; V606-S608 PolarHBondContact O-N 2.9Å
609Y96.7Very high93.5Very high9 Ų940.7 Ų40.74%0.03521%0.209CC..THydrogen-bonded Turntrans-107.80.3-176.5-65-78.6000114.5H448 N458 I460 T604 N605 V606 H611 W612 I613H448-Y609 AromaticContact CD2-CD1 3.86Å; H448-Y609 AromaticContact CD2-CE1 3.86Å; H448-Y609 AromaticContact NE2-CE1 3.82Å; N458-Y609 WeakPolarHBondContact CA-OH 3.32Å; N458-Y609 HydrophobicContact CB-CE1 4.16Å; N458-Y609 WeakPolarHBondContact OD1-CE1 3.37Å; N458-Y609 PolarHBondContact OD1-OH 2.77Å; I460-Y609 HydrophobicContact CD1-CD2 4.2Å; I460-Y609 HydrophobicContact CD1-CG 4.04Å; I460-Y609 HydrophobicContact CG2-CD1 4.03Å; I460-Y609 HydrophobicContact CG2-CE1 4.34Å; I460-Y609 HydrophobicContact CG2-CG 4.16Å; T604-Y609 HydrophobicContact CG2-CD2 3.83Å; T604-Y609 HydrophobicContact CG2-CE2 3.41Å; T604-Y609 VanDerWaalsContact CG2-CE2 3.41Å; N605-Y609 WeakPolarHBondContact O-CD2 3.31Å; V606-Y609 PolarHBondContact O-N 2.9Å; Y609-H611 VanDerWaalsContact C-N 3.32Å; Y609-H611 PolarHBondContact O-N 2.91Å; Y609-W612 CarbonylContact O-C 3.14Å; Y609-W612 WeakPolarHBondContact O-CA 3.47Å; Y609-W612 WeakPolarHBondContact O-CB 3.44Å; Y609-W612 PolarHBondContact O-N 2.93Å; Y609-I613 WeakPolarHBondContact O-CG1 3.38Å; Y609-I613 PolarHBondContact O-N 3.33Å
610I97.3Very high94.4Very high7 Ų736.8 Ų36.84%0.03619%0.191CC..Hα-helixtrans-52.2-42.9-175.7-59.6-61000113.8L480 P481 P483 V606 I613 K614L480-I610 HydrophobicContact CB-CD1 3.97Å; L480-I610 HydrophobicContact CD1-CD1 4.42Å; P481-I610 HydrophobicContact CG-CD1 4.15Å; P481-I610 VanDerWaalsContact O-CD1 3.28Å; P481-I610 WeakPolarHBondContact O-CD1 3.45Å; P481-I610 WeakPolarHBondContact O-CG1 3.11Å; P483-I610 HydrophobicContact CG-CB 4.12Å; P483-I610 HydrophobicContact CG-CG2 3.9Å; V606-I610 HydrophobicContact CG1-CD1 4.15Å; V606-I610 PolarHBondContact O-N 2.81Å; I610-I613 HydrophobicContact CD1-CD1 4.42Å; I610-I613 PolarHBondContact O-N 2.99Å; I610-K614 WeakPolarHBondContact O-CG 3.32Å; I610-K614 PolarHBondContact O-N 2.05Å; I610-K614 VanDerWaalsContact O-N 3.13Å
611H96.3Very high94.9Very high142 Ų14241.5 Ų41.566%0.65722%0.22SC*.Hα-helixtrans-64.6-40.7176.5-70.9-79.2000112.2Y609 Q615Y609-H611 VanDerWaalsContact C-N 3.32Å; Y609-H611 PolarHBondContact O-N 2.91Å; H611-Q615 PolarHBondContact O-N 3.5Å; H611-Q615 VanDerWaalsContact O-N 3.09Å
612W97.2Very high95.3Very high26 Ų2644.5 Ų44.510%0.09823%0.233CC..Hα-helixtrans-69.5-38.6176.5172.481000112V446 T447 H448 I460 V462 Y609 K614 Q615 A616V446-W612 HydrophobicContact CG1-CZ2 4.14Å; T447-W612 VanDerWaalsContact C-CZ2 3.47Å; H448-W612 VanDerWaalsContact CA-CZ2 3.48Å; H448-W612 HydrophobicContact CB-CD2 4.35Å; H448-W612 HydrophobicContact CB-CH2 4.39Å; H448-W612 HydrophobicContact CB-CZ2 3.96Å; H448-W612 AromaticContact CD2-CD1 3.66Å; H448-W612 AromaticContact CD2-CD2 3.78Å; H448-W612 AromaticContact CD2-CE2 3.96Å; H448-W612 AromaticContact CD2-CG 3.63Å; H448-W612 AromaticContact CD2-NE1 3.83Å; H448-W612 VanDerWaalsContact N-CZ2 3.26Å; I460-W612 HydrophobicContact CB-CZ3 4.3Å; I460-W612 HydrophobicContact CD1-CE3 4.5Å; I460-W612 HydrophobicContact CD1-CZ3 4.13Å; I460-W612 HydrophobicContact CG1-CZ3 3.91Å; I460-W612 HydrophobicContact CG2-CE3 4.02Å; I460-W612 HydrophobicContact CG2-CH2 4.15Å; I460-W612 HydrophobicContact CG2-CZ3 3.66Å; V462-W612 HydrophobicContact CG2-CH2 3.85Å; V462-W612 HydrophobicContact CG2-CZ3 3.78Å; Y609-W612 CarbonylContact O-C 3.14Å; Y609-W612 WeakPolarHBondContact O-CA 3.47Å; Y609-W612 WeakPolarHBondContact O-CB 3.44Å; Y609-W612 PolarHBondContact O-N 2.93Å; W612-K614 VanDerWaalsContact C-N 3.33Å; W612-K614 PolarHBondContact O-N 3.18Å; W612-Q615 PolarHBondContact O-N 2.93Å; W612-A616 HydrophobicContact CH2-CB 4.21Å; W612-A616 HydrophobicContact CZ2-CB 3.89Å; W612-A616 VanDerWaalsContact O-CB 3.32Å; W612-A616 WeakPolarHBondContact O-CB 3.1Å; W612-A616 PolarHBondContact O-N 2.82Å
613I97.7Very high95.4Very high0 Ų044.5 Ų44.50%023%0.233CC..Hα-helixtrans-58.8-46175.6-67.6168.6000110.2I389 L391 L401 I460 V462 L480 V606 Y609 I610 Q615 A616 D617I389-I613 HydrophobicContact CD1-CG2 3.98Å; L391-I613 HydrophobicContact CD1-CG2 4.27Å; L391-I613 HydrophobicContact CD2-CG2 4.14Å; L401-I613 HydrophobicContact CD1-CD1 3.91Å; L401-I613 HydrophobicContact CD1-CG1 4.11Å; L401-I613 HydrophobicContact CD2-CD1 4.21Å; I460-I613 HydrophobicContact CD1-CD1 4.07Å; I460-I613 HydrophobicContact CD1-CG1 4.28Å; V462-I613 HydrophobicContact CG2-CB 4.42Å; V462-I613 HydrophobicContact CG2-CG1 4.34Å; V462-I613 HydrophobicContact CG2-CG2 4.11Å; L480-I613 HydrophobicContact CD1-CG2 4.35Å; V606-I613 HydrophobicContact CG1-CD1 3.97Å; Y609-I613 WeakPolarHBondContact O-CG1 3.38Å; Y609-I613 PolarHBondContact O-N 3.33Å; I610-I613 HydrophobicContact CD1-CD1 4.42Å; I610-I613 PolarHBondContact O-N 2.99Å; I613-Q615 PolarHBondContact O-N 3.38Å; I613-A616 PolarHBondContact O-N 3.31Å; I613-D617 PolarHBondContact O-N 3.1Å
614K96.7Very high95.1Very high118 Ų11849.3 Ų49.351%0.51327%0.267SS..Hα-helixtrans-63.5-37.8176.2-70.8178.1178.3-176.90112.8L391 I610 W612 S618L391-K614 HydrophobicContact CD2-CG 4.28Å; I610-K614 WeakPolarHBondContact O-CG 3.32Å; I610-K614 PolarHBondContact O-N 2.05Å; I610-K614 VanDerWaalsContact O-N 3.13Å; W612-K614 VanDerWaalsContact C-N 3.33Å; W612-K614 PolarHBondContact O-N 3.18Å; K614-S618 PolarHBondContact O-N 3.34Å; K614-S618 VanDerWaalsContact O-N 3.16Å
615Q96.5Very high95Very high117 Ų11755.1 Ų55.155%0.54729%0.294SS..Hα-helixtrans-70.2-40.5175.2-172.4-177.930.900112.3H611 W612 I613 D617 S618 L619H611-Q615 PolarHBondContact O-N 3.5Å; H611-Q615 VanDerWaalsContact O-N 3.09Å; W612-Q615 PolarHBondContact O-N 2.93Å; I613-Q615 PolarHBondContact O-N 3.38Å; Q615-D617 VanDerWaalsContact C-N 3.32Å; Q615-D617 PolarHBondContact O-N 3.18Å; Q615-S618 PolarHBondContact O-N 3.1Å; Q615-S618 PolarHBondContact O-OG 2.87Å; Q615-S618 VanDerWaalsContact O-OG 3.11Å; Q615-L619 HydrophobicContact CG-CD1 4.33Å; Q615-L619 VanDerWaalsContact O-CG 3.25Å; Q615-L619 WeakPolarHBondContact O-CG 3.25Å; Q615-L619 PolarHBondContact O-N 3.42Å; Q615-L619 VanDerWaalsContact O-N 3.16Å
616A96.1Very high94.8Very high1 Ų158.4 Ų58.41%0.00831%0.311CS..Hα-helixtrans-64.3-38.4176.700000111.3V446 V462 W612 I613 M620V446-A616 HydrophobicContact CB-CB 4.11Å; V446-A616 HydrophobicContact CG1-CB 4Å; V462-A616 HydrophobicContact CB-CB 4.13Å; V462-A616 HydrophobicContact CG2-CB 3.83Å; W612-A616 HydrophobicContact CH2-CB 4.21Å; W612-A616 HydrophobicContact CZ2-CB 3.89Å; W612-A616 VanDerWaalsContact O-CB 3.32Å; W612-A616 WeakPolarHBondContact O-CB 3.1Å; W612-A616 PolarHBondContact O-N 2.82Å; I613-A616 PolarHBondContact O-N 3.31Å; A616-M620 WeakPolarHBondContact O-CE 3.34Å
617D94.4Very high94.6Very high15 Ų1559.1 Ų59.18%0.0831%0.314CS..Hα-helixtrans-63.3-48.4173.8-166.987.4000111.9L391 T399 R464 I613 Q615 L619 M620L391-D617 HydrophobicContact CD1-CB 3.43Å; L391-D617 VanDerWaalsContact CD1-CB 3.43Å; L391-D617 VanDerWaalsContact CD1-CG 3.49Å; T399-D617 WeakPolarHBondContact CG2-OD1 3.44Å; T399-D617 PolarHBondContact OG1-OD1 3.43Å; R464-D617 IonicContact CZ-OD1 2.68Å; R464-D617 IonicContact CZ-OD2 3.97Å; R464-D617 IonicContact NH1-OD1 2.68Å; R464-D617 IonicContact NH1-OD2 2.64Å; R464-D617 PolarHBondContact NH2-O 2.77Å; R464-D617 IonicContact NH2-OD1 2.9Å; R464-D617 PolarHBondContact NH2-OD1 3.47Å; R464-D617 IonicContact NH2-OD2 2.81Å; R464-D617 PolarHBondContact NH2-OD2 2.96Å; I613-D617 PolarHBondContact O-N 3.1Å; Q615-D617 VanDerWaalsContact C-N 3.32Å; Q615-D617 PolarHBondContact O-N 3.18Å; D617-L619 PolarHBondContact O-N 3.34Å; D617-M620 PolarHBondContact O-N 3.49Å
618S94Very high94.1Very high94 Ų9461 Ų6166%0.65733%0.326SS*.Hα-helixtrans-67.9-19.4-178.470.30000114.6K614 Q615 M620K614-S618 PolarHBondContact O-N 3.34Å; K614-S618 VanDerWaalsContact O-N 3.16Å; Q615-S618 PolarHBondContact O-N 3.1Å; Q615-S618 PolarHBondContact O-OG 2.87Å; Q615-S618 VanDerWaalsContact O-OG 3.11Å; S618-M620 VanDerWaalsContact C-N 3.33Å
619L93.7Very high93.1Very high126 Ų12661.4 Ų61.466%0.6633%0.329SS*.THydrogen-bonded Turntrans-78.8-12.6172.2-71.7169.3000113.7Q615 D617Q615-L619 HydrophobicContact CG-CD1 4.33Å; Q615-L619 VanDerWaalsContact O-CG 3.25Å; Q615-L619 WeakPolarHBondContact O-CG 3.25Å; Q615-L619 PolarHBondContact O-N 3.42Å; Q615-L619 VanDerWaalsContact O-N 3.16Å; D617-L619 PolarHBondContact O-N 3.34Å
620M94.9Very high92.1Very high14 Ų1466.2 Ų66.27%0.06935%0.352CS..SBendtrans-106.3136-176.7-68.3-169.9-71.900112.3S444 V446 V462 R464 A616 D617 S618 K622S444-M620 WeakPolarHBondContact OG-CG 3.45Å; S444-M620 PolarHBondContact OG-SD 3.39Å; V446-M620 HydrophobicContact CG2-CE 4.42Å; V446-M620 HydrophobicContact CG2-CG 3.78Å; V446-M620 HydrophobicContact CG2-SD 3.81Å; V462-M620 HydrophobicContact CB-CE 3.99Å; V462-M620 HydrophobicContact CG1-CE 3.69Å; R464-M620 HydrophobicContact CB-CB 4.16Å; R464-M620 HydrophobicContact CB-CE 4.01Å; R464-M620 HydrophobicContact CB-SD 3.62Å; R464-M620 HydrophobicContact CG-CB 4.37Å; R464-M620 PolarHBondContact NH2-O 3.11Å; A616-M620 WeakPolarHBondContact O-CE 3.34Å; D617-M620 PolarHBondContact O-N 3.49Å; S618-M620 VanDerWaalsContact C-N 3.33Å; M620-K622 PolarHBondContact O-N 3.16Å
621V93.8Very high91.3Very high109 Ų10970 Ų7066%0.66137%0.368SS*.  trans-68.8114.4177.4-174.30000110.1K443K443-V621 WeakPolarHBondContact CD-O 3.43Å; K443-V621 VanDerWaalsContact CE-O 3.27Å; K443-V621 WeakPolarHBondContact CE-O 3.39Å; K443-V621 PolarHBondContact NZ-O 3.16Å; K443-V621 VanDerWaalsContact NZ-O 3.08Å
622K93.7Very high90.2Very high76 Ų7663.6 Ų63.633%0.3334%0.339SS..  trans-49.6153.2178.3-59.5-158.3175.4178.70113.3E392 D398 K443 M620E392-K622 IonicContact OE1-NZ 2.65Å; E392-K622 PolarHBondContact OE1-NZ 2.98Å; E392-K622 IonicContact OE2-NZ 3.33Å; E392-K622 PolarHBondContact OE2-NZ 2.72Å; D398-K622 WeakPolarHBondContact OD2-CA 3.13Å; K443-K622 PolarHBondContact NZ-O 2.85Å; M620-K622 PolarHBondContact O-N 3.16Å
623A93.3Very high88.8Confident7 Ų770.9 Ų70.96%0.05837%0.366CS..  trans-57.7151.9171.300000111D398 Y468D398-A623 HydrophobicContact CB-CB 3.64Å; D398-A623 WeakPolarHBondContact OD2-CB 3.15Å; D398-A623 PolarHBondContact OD2-N 3.19Å; Y468-A623 HydrophobicContact CD1-CB 4.46Å; Y468-A623 HydrophobicContact CD2-CB 3.73Å; Y468-A623 HydrophobicContact CE1-CB 4.49Å; Y468-A623 HydrophobicContact CE2-CB 3.78Å; Y468-A623 WeakPolarHBondContact CE2-O 3.4Å; Y468-A623 HydrophobicContact CG-CB 4.07Å; Y468-A623 PolarHBondContact OH-O 3.28Å
624S85.6Confident87.1Confident100 Ų10073.5 Ų73.570%0.69938%0.379SS*.SBendtrans-106.7-13.9-177.149.60000113.8
625Q91.7Very high84.6Confident123 Ų12372.8 Ų72.858%0.57537%0.373SS*.SBendtrans-141155.1-173.2-67.5-178.2-0.400110.7H467 Y468H467-Q625 CarbonylContact C-O 3.56Å; H467-Q625 VanDerWaalsContact CA-O 3.28Å; H467-Q625 WeakPolarHBondContact CA-O 3.37Å; Y468-Q625 PolarHBondContact N-O 3.02Å
626L91.5Very high82.3Confident87 Ų8769.4 Ų69.446%0.45536%0.361SS..BIsolated β-bridgetrans-83.5143.2174-166.365.1000110.1Q396 P470Q396-L626 HydrophobicContact CB-CD1 4.05Å; P470-L626 HydrophobicContact CB-CD1 3.98Å; P470-L626 HydrophobicContact CB-CD2 4.45Å; P470-L626 HydrophobicContact CB-CG 4.41Å; P470-L626 HydrophobicContact CG-CD1 4.24Å; P470-L626 HydrophobicContact CG-CG 4.33Å
627F91.3Very high79.4Confident14 Ų1470.9 Ų70.96%0.06137%0.371CS..PPolyproline II helixtrans-73.8136.7171.8-168.8-108000110.2R437 I440 H467 Y468 S629 F631 I632R437-F627 VanDerWaalsContact O-CZ 3.29Å; R437-F627 WeakPolarHBondContact O-CZ 3.41Å; I440-F627 HydrophobicContact CB-CD2 4.44Å; I440-F627 HydrophobicContact CB-CE2 4.49Å; I440-F627 HydrophobicContact CD1-CB 3.9Å; I440-F627 HydrophobicContact CD1-CD1 4Å; I440-F627 HydrophobicContact CD1-CD2 4.03Å; I440-F627 HydrophobicContact CD1-CG 3.7Å; I440-F627 HydrophobicContact CG1-CB 4.49Å; I440-F627 HydrophobicContact CG1-CD1 4.1Å; I440-F627 HydrophobicContact CG1-CD2 3.67Å; I440-F627 HydrophobicContact CG1-CE1 4.19Å; I440-F627 HydrophobicContact CG1-CE2 3.77Å; I440-F627 HydrophobicContact CG1-CG 3.82Å; I440-F627 HydrophobicContact CG1-CZ 4.01Å; I440-F627 HydrophobicContact CG2-CD2 4.32Å; H467-F627 HydrophobicContact CB-CB 3.93Å; H467-F627 HydrophobicContact CB-CD2 4.23Å; Y468-F627 VanDerWaalsContact O-CB 3.24Å; Y468-F627 WeakPolarHBondContact O-CB 3.33Å; Y468-F627 PolarHBondContact O-N 2.82Å; F627-S629 PolarHBondContact O-N 3.43Å; F627-S629 VanDerWaalsContact O-N 3.13Å; F627-F631 HydrophobicContact CE1-CB 3.85Å; F627-F631 HydrophobicContact CE1-CD2 4.18Å; F627-F631 HydrophobicContact CE2-CD2 4.45Å; F627-F631 HydrophobicContact CZ-CB 4.26Å; F627-F631 AromaticContact CZ-CD2 3.92Å; F627-F631 HydrophobicContact CZ-CD2 3.92Å; F627-I632 HydrophobicContact CD1-CD1 4.13Å; F627-I632 HydrophobicContact CD1-CG1 3.95Å; F627-I632 HydrophobicContact CE1-CG1 4.19Å
628P86.4Confident76.4Confident43 Ų4374.6 Ų74.628%0.27940%0.395SS..PPolyproline II helixtrans-62.4117.1-174.3-22.734.2000112.4E630 F631P628-E630 VanDerWaalsContact C-OE2 3.25Å; P628-E630 VanDerWaalsContact CB-CD 3.4Å; P628-E630 HydrophobicContact CB-CG 4.2Å; P628-E630 WeakPolarHBondContact CB-OE1 3.45Å; P628-E630 WeakPolarHBondContact CB-OE2 3.45Å; P628-E630 PolarHBondContact O-N 3.24Å; P628-F631 HydrophobicContact CB-CD2 3.8Å; P628-F631 HydrophobicContact CB-CE2 3.86Å; P628-F631 HydrophobicContact CB-CG 4.26Å; P628-F631 HydrophobicContact CB-CZ 4.36Å; P628-F631 HydrophobicContact CG-CD2 3.92Å; P628-F631 HydrophobicContact CG-CE2 3.69Å; P628-F631 HydrophobicContact CG-CZ 4.44Å; P628-F631 WeakPolarHBondContact O-CB 3.39Å; P628-F631 PolarHBondContact O-N 3.19Å
629S77.3Confident73.6Confident62 Ų6273.5 Ų73.543%0.43438%0.382SS..G310 helixtrans-61.3-27-173.566.90000113.8F627 F631 I632F627-S629 PolarHBondContact O-N 3.43Å; F627-S629 VanDerWaalsContact O-N 3.13Å; S629-F631 PolarHBondContact O-N 2.81Å; S629-I632 CarbonylContact O-C 3.55Å; S629-I632 PolarHBondContact O-N 3.3Å; S629-I632 VanDerWaalsContact O-N 3.12Å
630E74.1Confident70.9Confident109 Ų10973 Ų7351%0.50938%0.376SS..G310 helixtrans-63.3-26.1175.161.5-90.4-143.800113P628 R633P628-E630 VanDerWaalsContact C-OE2 3.25Å; P628-E630 VanDerWaalsContact CB-CD 3.4Å; P628-E630 HydrophobicContact CB-CG 4.2Å; P628-E630 WeakPolarHBondContact CB-OE1 3.45Å; P628-E630 WeakPolarHBondContact CB-OE2 3.45Å; P628-E630 PolarHBondContact O-N 3.24Å; E630-R633 WeakPolarHBondContact O-CB 3.28Å; E630-R633 PolarHBondContact O-N 2.64Å
631F81Confident68.2Low88 Ų8875.8 Ų75.839%0.38639%0.391SS..G310 helixtrans-79.7-22.8174.9-59.9-20.5000112.4R437 K438 F627 P628 S629 R633R437-F631 HydrophobicContact CB-CB 4.39Å; R437-F631 WeakPolarHBondContact O-CB 3.35Å; K438-F631 WeakPolarHBondContact CE-O 3.46Å; K438-F631 WeakPolarHBondContact CG-O 3.21Å; F627-F631 HydrophobicContact CE1-CB 3.85Å; F627-F631 HydrophobicContact CE1-CD2 4.18Å; F627-F631 HydrophobicContact CE2-CD2 4.45Å; F627-F631 HydrophobicContact CZ-CB 4.26Å; F627-F631 AromaticContact CZ-CD2 3.92Å; F627-F631 HydrophobicContact CZ-CD2 3.92Å; P628-F631 HydrophobicContact CB-CD2 3.8Å; P628-F631 HydrophobicContact CB-CE2 3.86Å; P628-F631 HydrophobicContact CB-CG 4.26Å; P628-F631 HydrophobicContact CB-CZ 4.36Å; P628-F631 HydrophobicContact CG-CD2 3.92Å; P628-F631 HydrophobicContact CG-CE2 3.69Å; P628-F631 HydrophobicContact CG-CZ 4.44Å; P628-F631 WeakPolarHBondContact O-CB 3.39Å; P628-F631 PolarHBondContact O-N 3.19Å; S629-F631 PolarHBondContact O-N 2.81Å; F631-R633 PolarHBondContact O-N 2.81Å
632I73.3Confident65.5Low6 Ų675 Ų753%0.03138%0.382CS..G310 helixtrans-88.921.4172.2-32.3174.9000111I425 A426 P470 I474 F627 S629I425-I632 HydrophobicContact CD1-CD1 3.6Å; I425-I632 HydrophobicContact CD1-CG1 4Å; I425-I632 HydrophobicContact CD1-CG2 4.28Å; A426-I632 HydrophobicContact CB-CG2 3.71Å; P470-I632 HydrophobicContact CG-CD1 3.58Å; I474-I632 WeakPolarHBondContact CD1-O 3.31Å; I474-I632 HydrophobicContact CG1-CG2 4.34Å; F627-I632 HydrophobicContact CD1-CD1 4.13Å; F627-I632 HydrophobicContact CD1-CG1 3.95Å; F627-I632 HydrophobicContact CE1-CG1 4.19Å; S629-I632 CarbonylContact O-C 3.55Å; S629-I632 PolarHBondContact O-N 3.3Å; S629-I632 VanDerWaalsContact O-N 3.12Å
633R67.3Low62.9Low179 Ų17976.6 Ų76.668%0.67540%0.395SS*.SBendtrans-86.5146.6161.7-63.7-175.9-179.1-148.21.2108.7K438 E630 F631K438-R633 VanDerWaalsContact CE-O 3.29Å; K438-R633 WeakPolarHBondContact CE-O 3.42Å; E630-R633 WeakPolarHBondContact O-CB 3.28Å; E630-R633 PolarHBondContact O-N 2.64Å; F631-R633 PolarHBondContact O-N 2.81Å
634E61.7Low60Low56 Ų5683.9 Ų83.926%0.26243%0.428SS..  trans-63.5134.5166.9-176.9175147.300109.3K361 H362 V636K361-E634 VanDerWaalsContact CE-CD 3.48Å; K361-E634 WeakPolarHBondContact CE-OE1 3.38Å; K361-E634 WeakPolarHBondContact CE-OE2 3.27Å; K361-E634 IonicContact NZ-OE1 2.85Å; K361-E634 PolarHBondContact NZ-OE1 3.37Å; K361-E634 IonicContact NZ-OE2 3.63Å; H362-E634 IonicContact CD2-OE2 3.81Å; H362-E634 IonicContact CE1-OE2 3.1Å; H362-E634 IonicContact NE2-OE2 2.74Å; H362-E634 PolarHBondContact NE2-OE2 2.87Å; E634-V636 HydrophobicContact CB-CG2 4.33Å; E634-V636 HydrophobicContact CG-CG2 4.3Å; E634-V636 PolarHBondContact O-N 2.61Å
635Y45.2Very low57.5Low103 Ų10387.2 Ų87.240%0.40443%0.432SS..  trans-73.486163.3178.9-102.4000109.1D434 S637D434-Y635 PolarHBondContact OD2-N 3.42Å; Y635-S637 PolarHBondContact O-N 3.23Å
636V47.8Very low54.6Low46 Ų4686.3 Ų86.328%0.27944%0.437SS..  trans-65.6113.7162.9-176.10000106.2E634 E640 N641E634-V636 HydrophobicContact CB-CG2 4.33Å; E634-V636 HydrophobicContact CG-CG2 4.3Å; E634-V636 PolarHBondContact O-N 2.61Å; V636-E640 VanDerWaalsContact CG1-C 3.42Å; V636-E640 HydrophobicContact CG1-CB 3.39Å; V636-N641 HydrophobicContact CB-CB 4.48Å; V636-N641 HydrophobicContact CG1-CB 3.74Å
637S35.8Very low51.7Low31 Ų3193.2 Ų93.222%0.21746%0.457CS..  trans-60.4155.9177.867.20000110.1Y635 L639 E640 N641Y635-S637 PolarHBondContact O-N 3.23Å; S637-L639 PolarHBondContact O-N 3.4Å; S637-E640 VanDerWaalsContact CB-OE2 3.24Å; S637-E640 WeakPolarHBondContact CB-OE2 3.41Å; S637-E640 PolarHBondContact N-OE2 3.14Å; S637-E640 PolarHBondContact O-N 3.03Å; S637-E640 PolarHBondContact OG-N 2.95Å; S637-E640 PolarHBondContact OG-OE2 2.79Å; S637-N641 WeakPolarHBondContact O-CB 3.43Å; S637-N641 PolarHBondContact O-N 3.08Å
638P31.4Very low49Very low93 Ų93103.7 Ų103.760%0.60450%0.496SS*.THydrogen-bonded Turntrans-56.7-11.2177.8-27.235.9000115.3
639L35Very low46.4Very low71 Ų71110.1 Ų110.137%0.37252%0.522SS..THydrogen-bonded Turntrans-92.2-28.5175.8-60.9170.9000113.1P12 S637 N641 I642P12-L639 VanDerWaalsContact CD-CD2 3.42Å; P12-L639 HydrophobicContact CG-CD1 3.6Å; P12-L639 HydrophobicContact CG-CD2 3.77Å; P12-L639 HydrophobicContact CG-CG 4.29Å; S637-L639 PolarHBondContact O-N 3.4Å; L639-N641 VanDerWaalsContact C-N 3.34Å; L639-I642 WeakPolarHBondContact O-CD1 3.46Å; L639-I642 WeakPolarHBondContact O-CG1 3.04Å
640E37.7Very low44.1Very low115 Ų115113.6 Ų113.654%0.53754%0.541SS..THydrogen-bonded Turntrans-83.5-16.6168.7-64.7158.5127.500111V636 S637V636-E640 VanDerWaalsContact CG1-C 3.42Å; V636-E640 HydrophobicContact CG1-CB 3.39Å; S637-E640 VanDerWaalsContact CB-OE2 3.24Å; S637-E640 WeakPolarHBondContact CB-OE2 3.41Å; S637-E640 PolarHBondContact N-OE2 3.14Å; S637-E640 PolarHBondContact O-N 3.03Å; S637-E640 PolarHBondContact OG-N 2.95Å; S637-E640 PolarHBondContact OG-OE2 2.79Å
641N36.3Very low42.3Very low73 Ų73114.8 Ų114.839%0.3956%0.556SS.*  trans-97.222.6-175.1-143.3-8.9000113.8V636 S637 L639 D643V636-N641 HydrophobicContact CB-CB 4.48Å; V636-N641 HydrophobicContact CG1-CB 3.74Å; S637-N641 WeakPolarHBondContact O-CB 3.43Å; S637-N641 PolarHBondContact O-N 3.08Å; L639-N641 VanDerWaalsContact C-N 3.34Å; N641-D643 VanDerWaalsContact C-N 3.25Å; N641-D643 PolarHBondContact O-N 2.68Å
642I37.1Very low39.9Very low92 Ų92116.8 Ų116.847%0.47258%0.575SS.*THydrogen-bonded Turntrans-72.4-19.4-175.4-67.3177.2000112.2F11 L639F11-I642 HydrophobicContact CE1-CD1 4.08Å; L639-I642 WeakPolarHBondContact O-CD1 3.46Å; L639-I642 WeakPolarHBondContact O-CG1 3.04Å
643D39.8Very low38.3Very low111 Ų111121.8 Ų121.859%0.59461%0.61SS**THydrogen-bonded Turntrans-92.2-8.6-175.5-97.713.2000115.5N641 Q645N641-D643 VanDerWaalsContact C-N 3.25Å; N641-D643 PolarHBondContact O-N 2.68Å; D643-Q645 PolarHBondContact O-N 2.9Å
644E33Very low36.6Very low160 Ų160120 Ų12075%0.74861%0.614SS**  trans-92.672.2171.9-69.9-158.6167.100112.3
645Q32Very low35.6Very low169 Ų169132.1 Ų132.179%0.7966%0.66SS**  trans-58.1129.8164.9-83.2-95.3-25.300110.3D643 R647D643-Q645 PolarHBondContact O-N 2.9Å; Q645-R647 PolarHBondContact O-N 3.09Å
646P32.5Very low35.1Very low104 Ų104133.6 Ų133.668%0.67567%0.672SS**  trans-67.1124.4-178.326.8-33.6000110.2R648P646-R648 PolarHBondContact O-N 3.13Å
647R29.2Very low34.4Very low233 Ų233138.2 Ų138.288%0.87969%0.693SS**  trans-60.797.3169.5-68.3-174.9-174.9-176.22.8108.8Q645 H649Q645-R647 PolarHBondContact O-N 3.09Å; R647-H649 PolarHBondContact O-N 2.68Å; R647-H649 VanDerWaalsContact O-N 3.15Å
648R34.3Very low34.3Very low233 Ų233144.1 Ų144.188%0.87972%0.72SS**  trans-59.4119169.7-77.7-172175.4-166.5-0.9108.3P646 T650P646-R648 PolarHBondContact O-N 3.13Å; R648-T650 PolarHBondContact O-N 2.7Å
649H32.6Very low34.5Very low179 Ų179147.1 Ų147.183%0.82973%0.726SS**  trans-59.4118.3166-79.2-94.3000108.8R647 T651R647-H649 PolarHBondContact O-N 2.68Å; R647-H649 VanDerWaalsContact O-N 3.15Å; H649-T651 PolarHBondContact O-N 2.87Å; H649-T651 VanDerWaalsContact O-N 3.13Å
650T28.9Very low34.5Very low135 Ų135151.9 Ų151.983%0.82875%0.749SS**  trans-74.793.4168.4450000109.3R648R648-T650 PolarHBondContact O-N 2.7Å
651T35.8Very low34.3Very low133 Ų133154.3 Ų154.382%0.81676%0.763SS**  trans-84.2115.4159.639.60000109.2H649H649-T651 PolarHBondContact O-N 2.87Å; H649-T651 VanDerWaalsContact O-N 3.13Å
652V31.7Very low34.1Very low131 Ų131160.1 Ų160.179%0.79479%0.789SS**  trans-77.9127.3170.8177.80000108.9
653S38.2Very low33.9Very low110 Ų110165.4 Ų165.477%0.76981%0.814SS**  trans-152129.315663.30000110.2
654N33.6Very low33.4Very low143 Ų143169.9 Ų169.977%0.76583%0.832SS**  trans-65.8145.1-175.3-48.1-48000112.5
655Y38.9Very low33.4Very low309 Ų309170.8 Ų170.8100%1.21284%0.84SS**  -160.90124.7-102-68.4000109.9

Retrieved 655 of 655 residues in 725.7 ms (Link to these results)