A0A077ZGP7_TRITR Loading...

2-isopropylmalate synthase

AlphaFold DB , UniProt , Accession A0A077ZGP7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 520 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M83.1Confident96.1Very high136 Ų13633.5 Ų33.567%0.6715%0.15SC*.  0143.70-156.8167.4-66.900108.1E251 Q255 T257M1-E251 HydrophobicContact CE-CG 3.66Å; M1-E251 WeakPolarHBondContact CE-OE1 3.17Å; M1-E251 HydrophobicContact SD-CG 3.26Å; M1-E251 WeakPolarHBondContact SD-CG 3.43Å; M1-Q255 WeakPolarHBondContact CG-O 3.48Å; M1-T257 HydrophobicContact CB-CG2 4.12Å; M1-T257 HydrophobicContact CG-CG2 3.96Å; M1-T257 HydrophobicContact SD-CG2 3.41Å; M1-T257 WeakPolarHBondContact SD-CG2 3.22Å
2R92.1Very high96.2Very high78 Ų7833.1 Ų33.129%0.29415%0.147SC..EExtended strand (participates in β ladder)trans-79.1140.4-179.2-173.5172.164.579.6-11.9109.5I217 A221 G222 Q255 A256 T257R2-I217 PolarHBondContact NH2-O 2.92Å; R2-A221 VanDerWaalsContact NH1-C 3.32Å; R2-A221 PolarHBondContact NH1-O 3.23Å; R2-A221 PolarHBondContact NH2-O 3.1Å; R2-G222 VanDerWaalsContact NH1-CA 3.29Å; R2-Q255 PolarHBondContact N-O 3.06Å; R2-Q255 VanDerWaalsContact N-O 3.17Å; R2-A256 CarbonylContact O-C 3Å; R2-A256 WeakPolarHBondContact O-CA 3.21Å; R2-T257 PolarHBondContact O-N 2.99Å
3K95.9Very high96.2Very high103 Ų10330.8 Ų30.845%0.44814%0.137SC..EExtended strand (participates in β ladder)trans-91.6133.4174-174.8171.3169.5171.10109.6T257 D259K3-T257 CarbonylContact C-O 3.56Å; K3-T257 WeakPolarHBondContact CA-O 3.07Å; K3-D259 WeakPolarHBondContact CE-OD1 3.07Å; K3-D259 WeakPolarHBondContact CE-OD2 3.29Å; K3-D259 IonicContact NZ-OD1 2.96Å; K3-D259 PolarHBondContact NZ-OD1 3.45Å; K3-D259 IonicContact NZ-OD2 2.78Å; K3-D259 PolarHBondContact NZ-OD2 2.78Å
4V98.2Very high96.1Very high1 Ų128.6 Ų28.61%0.00613%0.127CC..  trans-105.1121.6173.6175.90000108.2F6 I217 G222 V224 L247 A256 T257V4-F6 HydrophobicContact CG1-CE2 4.19Å; V4-I217 HydrophobicContact CG1-CD1 4.3Å; V4-I217 HydrophobicContact CG2-CG2 3.94Å; V4-G222 WeakPolarHBondContact CA-O 3.46Å; V4-V224 HydrophobicContact CG1-CG1 4.24Å; V4-L247 HydrophobicContact CB-CD1 4.06Å; V4-L247 HydrophobicContact CG1-CD1 4.18Å; V4-L247 HydrophobicContact CG2-CD1 4.28Å; V4-A256 HydrophobicContact CG2-CB 3.84Å; V4-T257 PolarHBondContact N-O 3.05Å
5E98.4Very high95.8Very high47 Ų4729.7 Ų29.722%0.2213%0.133CC..EExtended strand (participates in β ladder)trans-78.5145173.3-65.6179.5-178.500110.7A40 Y164 G222 R223 V224E5-A40 HydrophobicContact CB-CB 3.99Å; E5-A40 HydrophobicContact CG-CB 4.26Å; E5-Y164 PolarHBondContact OE1-OH 3.04Å; E5-Y164 WeakPolarHBondContact OE2-CE1 3.38Å; E5-Y164 PolarHBondContact OE2-OH 3.2Å; E5-Y164 VanDerWaalsContact OE2-OH 3.04Å; E5-G222 PolarHBondContact N-O 2.85Å; E5-R223 HydrophobicContact CB-CB 4.2Å; E5-R223 HydrophobicContact CB-CG 4.22Å; E5-R223 CarbonylContact O-C 3.52Å; E5-R223 WeakPolarHBondContact O-CA 3.45Å; E5-R223 IonicContact OE2-CZ 3.01Å; E5-R223 IonicContact OE2-NE 2.61Å; E5-R223 PolarHBondContact OE2-NE 3.43Å; E5-R223 VanDerWaalsContact OE2-NE 3.11Å; E5-R223 IonicContact OE2-NH2 3.98Å; E5-R223 PolarHBondContact OE2-NH2 3.12Å; E5-V224 PolarHBondContact O-N 3.46Å
6F98.7Very high95.3Very high4 Ų432.9 Ų32.92%0.01815%0.148CC..EExtended strand (participates in β ladder)trans-108.8122.7173.1-78.1-119.7000108.5V4 I39 A40 S41 V224 L240 I243 A244 L247 S258 I260V4-F6 HydrophobicContact CG1-CE2 4.19Å; F6-I39 HydrophobicContact CB-CD1 3.75Å; F6-A40 PolarHBondContact O-N 2.59Å; F6-S41 PolarHBondContact O-N 3.04Å; F6-V224 HydrophobicContact CB-CG1 4.32Å; F6-V224 HydrophobicContact CD1-CG1 3.7Å; F6-V224 HydrophobicContact CD2-CG1 3.86Å; F6-V224 HydrophobicContact CE1-CG1 3.86Å; F6-V224 HydrophobicContact CE2-CG1 3.99Å; F6-V224 HydrophobicContact CG-CG1 3.7Å; F6-V224 HydrophobicContact CZ-CG1 4Å; F6-L240 HydrophobicContact CD1-CB 4.39Å; F6-L240 HydrophobicContact CD1-CD2 4.02Å; F6-L240 HydrophobicContact CE1-CD2 4.49Å; F6-I243 HydrophobicContact CE1-CB 4.06Å; F6-I243 HydrophobicContact CE1-CG2 4.05Å; F6-I243 HydrophobicContact CZ-CB 4.23Å; F6-I243 HydrophobicContact CZ-CG2 3.78Å; F6-A244 HydrophobicContact CE1-CB 3.83Å; F6-A244 HydrophobicContact CZ-CB 3.99Å; F6-L247 HydrophobicContact CE2-CD1 4.01Å; F6-L247 HydrophobicContact CZ-CD1 4.03Å; F6-S258 VanDerWaalsContact CE2-CB 3.47Å; F6-I260 HydrophobicContact CB-CD1 3.98Å; F6-I260 HydrophobicContact CD1-CD1 3.97Å; F6-I260 HydrophobicContact CD1-CG1 4.01Å; F6-I260 HydrophobicContact CD2-CD1 4.26Å; F6-I260 HydrophobicContact CD2-CG1 3.9Å; F6-I260 HydrophobicContact CE1-CG1 4.16Å; F6-I260 HydrophobicContact CE2-CG1 4.08Å; F6-I260 HydrophobicContact CG-CD1 3.81Å; F6-I260 HydrophobicContact CG-CG1 3.89Å; F6-I260 HydrophobicContact CZ-CG1 4.2Å
7L98.7Very high94.8Very high0 Ų032.1 Ų32.10%015%0.146CC..EExtended strand (participates in β ladder)trans-104.5121168.2-172.9157.5000108.6T9 S41 E43 R223 V224 E225 G226L7-T9 HydrophobicContact CD2-CG2 3.42Å; L7-T9 VanDerWaalsContact CD2-CG2 3.42Å; L7-S41 CarbonylContact C-O 3.39Å; L7-S41 WeakPolarHBondContact CA-O 3.3Å; L7-E43 HydrophobicContact CD2-CB 3.94Å; L7-R223 HydrophobicContact CB-CG 4.17Å; L7-V224 PolarHBondContact N-O 3.49Å; L7-E225 HydrophobicContact CB-CG 3.78Å; L7-E225 HydrophobicContact CD1-CG 4.19Å; L7-E225 HydrophobicContact CD2-CG 3.72Å; L7-E225 HydrophobicContact CG-CG 4.06Å; L7-E225 WeakPolarHBondContact O-CA 3.47Å; L7-G226 PolarHBondContact O-N 2.89Å
8D98.7Very high94.1Very high0 Ų036.7 Ų36.70%018%0.18CC..EExtended strand (participates in β ladder)trans-93128.4175.8179-85000111T10 L34 I39 S41 E43 L240D8-T10 VanDerWaalsContact CG-OG1 3.25Å; D8-T10 WeakPolarHBondContact OD1-CA 3.47Å; D8-T10 WeakPolarHBondContact OD1-CB 3.49Å; D8-T10 PolarHBondContact OD1-N 2.71Å; D8-T10 PolarHBondContact OD1-OG1 2.95Å; D8-T10 VanDerWaalsContact OD1-OG1 3.12Å; D8-T10 PolarHBondContact OD2-OG1 3.07Å; D8-L34 HydrophobicContact CB-CD1 4.02Å; D8-L34 HydrophobicContact CB-CD2 4.22Å; D8-L34 VanDerWaalsContact CG-CD1 3.49Å; D8-L34 WeakPolarHBondContact OD1-CD1 3.35Å; D8-I39 HydrophobicContact CB-CD1 4.14Å; D8-I39 HydrophobicContact CB-CG1 4.25Å; D8-I39 HydrophobicContact CB-CG2 3.9Å; D8-S41 PolarHBondContact N-O 3.11Å; D8-E43 PolarHBondContact O-N 3.47Å; D8-L240 HydrophobicContact CB-CD1 3.91Å
9T98.4Very high93.4Very high0 Ų039.2 Ų39.20%022%0.215CC..  trans-109.514.5175.464.70000112.5L7 L11 R12 D13 G14 E43 E225 G226 T227L7-T9 HydrophobicContact CD2-CG2 3.42Å; L7-T9 VanDerWaalsContact CD2-CG2 3.42Å; T9-L11 PolarHBondContact O-N 3.12Å; T9-R12 CarbonylContact O-C 3.53Å; T9-R12 PolarHBondContact O-N 2.86Å; T9-D13 PolarHBondContact O-N 3.35Å; T9-G14 PolarHBondContact O-N 2.86Å; T9-G14 VanDerWaalsContact O-N 3.08Å; T9-E43 HydrophobicContact CG2-CB 4.03Å; T9-E225 HydrophobicContact CG2-CB 4.48Å; T9-G226 PolarHBondContact N-O 3.32Å; T9-G226 PolarHBondContact OG1-O 3.07Å; T9-T227 WeakPolarHBondContact OG1-CG2 3.38Å
10T98Very high93Very high0 Ų037.8 Ų37.80%021%0.208CC..THydrogen-bonded Turntrans-56.5-37.7-177.5-60.10000111.3D8 R12 G14 E15 T227 V228 I231 I272D8-T10 VanDerWaalsContact CG-OG1 3.25Å; D8-T10 WeakPolarHBondContact OD1-CA 3.47Å; D8-T10 WeakPolarHBondContact OD1-CB 3.49Å; D8-T10 PolarHBondContact OD1-N 2.71Å; D8-T10 PolarHBondContact OD1-OG1 2.95Å; D8-T10 VanDerWaalsContact OD1-OG1 3.12Å; D8-T10 PolarHBondContact OD2-OG1 3.07Å; T10-R12 VanDerWaalsContact C-N 3.3Å; T10-R12 PolarHBondContact O-N 3.41Å; T10-G14 CarbonylContact O-C 3.55Å; T10-G14 VanDerWaalsContact O-CA 3.27Å; T10-G14 WeakPolarHBondContact O-CA 3.5Å; T10-G14 PolarHBondContact O-N 2.92Å; T10-E15 PolarHBondContact O-N 3.46Å; T10-T227 WeakPolarHBondContact OG1-CA 3.15Å; T10-V228 PolarHBondContact OG1-N 2.57Å; T10-V228 VanDerWaalsContact OG1-N 3.11Å; T10-I231 HydrophobicContact CG2-CD1 3.79Å; T10-I231 HydrophobicContact CG2-CG1 4.4Å; T10-I272 HydrophobicContact CG2-CD1 4.02Å; T10-I272 HydrophobicContact CG2-CG1 4.39Å; T10-I272 HydrophobicContact CG2-CG2 3.91Å
11L97.3Very high92.6Very high0 Ų042.2 Ų42.20%023%0.232CC..THydrogen-bonded Turntrans-80.3-4.6-178.2-61.6-176.4000114.9T9 K27 I30 A31 I42 I60T9-L11 PolarHBondContact O-N 3.12Å; L11-K27 HydrophobicContact CD2-CB 4.09Å; L11-K27 HydrophobicContact CD2-CG 4.09Å; L11-I30 HydrophobicContact CD1-CG2 4.47Å; L11-I30 HydrophobicContact CD2-CB 3.89Å; L11-I30 HydrophobicContact CD2-CD1 3.93Å; L11-I30 HydrophobicContact CD2-CG2 3.66Å; L11-I30 HydrophobicContact CG-CG2 4.14Å; L11-A31 HydrophobicContact CD1-CB 4.05Å; L11-I42 HydrophobicContact CD1-CG2 3.92Å; L11-I60 HydrophobicContact CD1-CD1 3.64Å
12R96.6Very high92.8Very high28 Ų2836 Ų3611%0.10620%0.201CC..THydrogen-bonded Turntrans-125.2-68177.3-169.1-75.3-61.5163.71.8111.5T9 T10 E43 L72T9-R12 CarbonylContact O-C 3.53Å; T9-R12 PolarHBondContact O-N 2.86Å; T10-R12 VanDerWaalsContact C-N 3.3Å; T10-R12 PolarHBondContact O-N 3.41Å; R12-E43 HydrophobicContact CB-CG 4.01Å; R12-E43 HydrophobicContact CG-CG 4.29Å; R12-E43 IonicContact CZ-OE1 3.81Å; R12-E43 IonicContact NE-OE1 3.58Å; R12-E43 PolarHBondContact NE-OE1 2.87Å; R12-E43 IonicContact NH2-OE1 3.12Å; R12-E43 PolarHBondContact NH2-OE1 3.25Å; R12-L72 HydrophobicContact CG-CD2 4.5Å
13D96Very high92.4Very high4 Ų434.9 Ų34.92%0.02121%0.205CC..THydrogen-bonded Turntrans-72.1-42.3-179.6-149-55.5000110.7T9 E15 Q16 H201 H203 G232 N237T9-D13 PolarHBondContact O-N 3.35Å; D13-E15 PolarHBondContact O-N 3.28Å; D13-Q16 VanDerWaalsContact O-CB 3.23Å; D13-Q16 WeakPolarHBondContact O-CB 2.88Å; D13-Q16 PolarHBondContact O-N 3.41Å; D13-H201 IonicContact OD2-CE1 3.61Å; D13-H201 IonicContact OD2-NE2 3.23Å; D13-H201 PolarHBondContact OD2-NE2 2.93Å; D13-H203 IonicContact OD1-CE1 3.49Å; D13-G232 WeakPolarHBondContact O-CA 3.4Å; D13-N237 PolarHBondContact OD1-ND2 3.49Å
14G94.9Very high92Very high0 Ų032 Ų320%019%0.194CC..G310 helixtrans-59.9-33.8176.900000113.7T9 T10 Q16 T17T9-G14 PolarHBondContact O-N 2.86Å; T9-G14 VanDerWaalsContact O-N 3.08Å; T10-G14 CarbonylContact O-C 3.55Å; T10-G14 VanDerWaalsContact O-CA 3.27Å; T10-G14 WeakPolarHBondContact O-CA 3.5Å; T10-G14 PolarHBondContact O-N 2.92Å; G14-Q16 PolarHBondContact O-N 3.3Å; G14-T17 WeakPolarHBondContact O-CB 3.37Å; G14-T17 PolarHBondContact O-N 3.4Å; G14-T17 PolarHBondContact O-OG1 2.98Å
15E91.5Very high91.3Very high45 Ų4540.5 Ų40.521%0.2123%0.231CC..G310 helixtrans-72.9-10.7175.5-165.5172.1-136.200113.3T10 D13 T17 F22 K27T10-E15 PolarHBondContact O-N 3.46Å; D13-E15 PolarHBondContact O-N 3.28Å; E15-T17 PolarHBondContact O-N 3.04Å; E15-F22 HydrophobicContact CB-CD2 4.18Å; E15-F22 HydrophobicContact CB-CE2 4.32Å; E15-F22 HydrophobicContact CG-CD2 4.12Å; E15-F22 PolarHBondContact OE1-N 3.45Å; E15-K27 VanDerWaalsContact CD-CE 3.49Å; E15-K27 VanDerWaalsContact CD-NZ 3.3Å; E15-K27 WeakPolarHBondContact OE1-CE 3.25Å; E15-K27 IonicContact OE1-NZ 2.74Å; E15-K27 PolarHBondContact OE1-NZ 3.34Å; E15-K27 VanDerWaalsContact OE2-CE 3.27Å; E15-K27 WeakPolarHBondContact OE2-CE 3.44Å; E15-K27 IonicContact OE2-NZ 2.81Å; E15-K27 PolarHBondContact OE2-NZ 2.84Å
16Q88.5Confident90.8Very high80 Ų8040.8 Ų40.837%0.37423%0.232SC..G310 helixtrans-77-6.6171.7-61.1-179.4-28.300112.6D13 G14 P18 E233D13-Q16 VanDerWaalsContact O-CB 3.23Å; D13-Q16 WeakPolarHBondContact O-CB 2.88Å; D13-Q16 PolarHBondContact O-N 3.41Å; G14-Q16 PolarHBondContact O-N 3.3Å; Q16-P18 WeakPolarHBondContact O-CD 3.49Å; Q16-E233 HydrophobicContact CB-CG 3.81Å; Q16-E233 WeakPolarHBondContact CB-OE1 3.47Å; Q16-E233 VanDerWaalsContact OE1-CG 3.29Å
17T87.1Confident90.6Very high20 Ų2041.2 Ų41.212%0.12323%0.234CC..SBendtrans-62.6126.8170.9-59.40000110.8G14 E15 G19 V20 G232 I278G14-T17 WeakPolarHBondContact O-CB 3.37Å; G14-T17 PolarHBondContact O-N 3.4Å; G14-T17 PolarHBondContact O-OG1 2.98Å; E15-T17 PolarHBondContact O-N 3.04Å; T17-G19 PolarHBondContact O-N 3.35Å; T17-V20 HydrophobicContact CG2-CG2 4Å; T17-V20 WeakPolarHBondContact O-CB 3.32Å; T17-V20 PolarHBondContact O-N 2.99Å; T17-G232 WeakPolarHBondContact OG1-CA 3.27Å; T17-G232 PolarHBondContact OG1-N 3.36Å; T17-G232 PolarHBondContact OG1-O 3.4Å; T17-I278 HydrophobicContact CG2-CD1 3.52Å
18P82.3Confident90.2Very high115 Ų11542 Ų4275%0.74724%0.239SC*.THydrogen-bonded Turntrans-53.2124.5178.1-28.435.6000112.6Q16Q16-P18 WeakPolarHBondContact O-CD 3.49Å
19G80.5Confident89.7Confident83 Ų8343.8 Ų43.886%0.85625%0.254SS*.THydrogen-bonded Turntrans93.5-12-179.700000114.9T17T17-G19 PolarHBondContact O-N 3.35Å
20V85.5Confident89.5Confident11 Ų1143.8 Ų43.87%0.06725%0.254CS..  trans-84.3128.9174.2-179.30000109.6T17 F22 I278T17-V20 HydrophobicContact CG2-CG2 4Å; T17-V20 WeakPolarHBondContact O-CB 3.32Å; T17-V20 PolarHBondContact O-N 2.99Å; V20-F22 HydrophobicContact CG1-CD1 4.45Å; V20-F22 HydrophobicContact CG1-CD2 4.05Å; V20-F22 HydrophobicContact CG1-CE1 4Å; V20-F22 HydrophobicContact CG1-CE2 3.53Å; V20-F22 HydrophobicContact CG1-CG 4.49Å; V20-F22 HydrophobicContact CG1-CZ 3.51Å; V20-I278 HydrophobicContact CG2-CD1 3.55Å; V20-I278 HydrophobicContact CG2-CG1 4.15Å
21N84.6Confident89.4Confident132 Ų13243.8 Ų43.871%0.70625%0.254SS*.  trans-152.6104.2173.4-175.5-14.3000108.7
22F85.7Confident89.3Confident5 Ų549.1 Ų49.12%0.02228%0.277CS..  trans-87.3129-177.6-58.5-64.7000110E15 V20 E26 K27 I30 I231 F275E15-F22 HydrophobicContact CB-CD2 4.18Å; E15-F22 HydrophobicContact CB-CE2 4.32Å; E15-F22 HydrophobicContact CG-CD2 4.12Å; E15-F22 PolarHBondContact OE1-N 3.45Å; V20-F22 HydrophobicContact CG1-CD1 4.45Å; V20-F22 HydrophobicContact CG1-CD2 4.05Å; V20-F22 HydrophobicContact CG1-CE1 4Å; V20-F22 HydrophobicContact CG1-CE2 3.53Å; V20-F22 HydrophobicContact CG1-CG 4.49Å; V20-F22 HydrophobicContact CG1-CZ 3.51Å; F22-E26 HydrophobicContact CB-CB 4.31Å; F22-K27 HydrophobicContact CB-CD 4.39Å; F22-K27 HydrophobicContact CB-CG 3.55Å; F22-K27 HydrophobicContact CG-CG 4.49Å; F22-K27 WeakPolarHBondContact O-CE 3.23Å; F22-I30 HydrophobicContact CD1-CD1 3.82Å; F22-I30 HydrophobicContact CD2-CD1 4.49Å; F22-I30 HydrophobicContact CE1-CD1 3.73Å; F22-I30 HydrophobicContact CE2-CD1 4.43Å; F22-I30 HydrophobicContact CG-CD1 4.19Å; F22-I30 HydrophobicContact CZ-CD1 4.06Å; F22-I231 HydrophobicContact CZ-CD1 4.33Å; F22-F275 HydrophobicContact CD1-CB 3.87Å; F22-F275 HydrophobicContact CE1-CB 3.77Å
23S83.7Confident89.2Confident54 Ų5449.6 Ų49.638%0.37828%0.278SS..  trans-62.7154.3165.769.60000110.8K25 E26 K27S23-K25 PolarHBondContact O-N 3.2Å; S23-K25 VanDerWaalsContact O-N 3.08Å; S23-E26 VanDerWaalsContact CB-OE2 3.24Å; S23-E26 WeakPolarHBondContact CB-OE2 3.48Å; S23-E26 PolarHBondContact N-OE2 3.28Å; S23-E26 WeakPolarHBondContact O-CA 3.42Å; S23-E26 WeakPolarHBondContact O-CB 3.21Å; S23-E26 PolarHBondContact O-N 2.89Å; S23-E26 VanDerWaalsContact OG-CG 3.29Å; S23-E26 WeakPolarHBondContact OG-CG 3.26Å; S23-E26 PolarHBondContact OG-N 3.05Å; S23-E26 PolarHBondContact OG-OE2 3.49Å; S23-K27 WeakPolarHBondContact O-CG 3.37Å; S23-K27 PolarHBondContact O-N 3.33Å
24I88.7Confident89.3Confident44 Ų4449.4 Ų49.423%0.22628%0.277CS..Hα-helixtrans-53.1-36.7177.4-63.4170.5000111.6K27 V28 E55 A56 Q59I24-K27 PolarHBondContact O-N 2.53Å; I24-V28 WeakPolarHBondContact O-CG2 3.14Å; I24-V28 PolarHBondContact O-N 3.37Å; I24-E55 HydrophobicContact CD1-CB 4.18Å; I24-E55 HydrophobicContact CD1-CG 3.89Å; I24-A56 HydrophobicContact CG1-CB 4.27Å; I24-Q59 HydrophobicContact CG2-CB 4.43Å; I24-Q59 HydrophobicContact CG2-CG 4.41Å
25K84Confident89.4Confident178 Ų17851 Ų5177%0.77429%0.285SS*.Hα-helixtrans-64.8-43.2176.6-69.2-177-179.6177.10112.2S23 V28 A29S23-K25 PolarHBondContact O-N 3.2Å; S23-K25 VanDerWaalsContact O-N 3.08Å; K25-V28 PolarHBondContact O-N 3.27Å; K25-A29 WeakPolarHBondContact O-CB 3.4Å; K25-A29 PolarHBondContact O-N 3.43Å
26E86.7Confident89.6Confident54 Ų5454.2 Ų54.225%0.25230%0.298SS..Hα-helixtrans-65.6-43176-71159.4150.500110.7F22 S23 V28 A29 I30 F275F22-E26 HydrophobicContact CB-CB 4.31Å; S23-E26 VanDerWaalsContact CB-OE2 3.24Å; S23-E26 WeakPolarHBondContact CB-OE2 3.48Å; S23-E26 PolarHBondContact N-OE2 3.28Å; S23-E26 WeakPolarHBondContact O-CA 3.42Å; S23-E26 WeakPolarHBondContact O-CB 3.21Å; S23-E26 PolarHBondContact O-N 2.89Å; S23-E26 VanDerWaalsContact OG-CG 3.29Å; S23-E26 WeakPolarHBondContact OG-CG 3.26Å; S23-E26 PolarHBondContact OG-N 3.05Å; S23-E26 PolarHBondContact OG-OE2 3.49Å; E26-V28 PolarHBondContact O-N 3.27Å; E26-A29 WeakPolarHBondContact O-CB 3.37Å; E26-A29 PolarHBondContact O-N 3.12Å; E26-A29 VanDerWaalsContact O-N 3.1Å; E26-I30 VanDerWaalsContact O-CG1 3.31Å; E26-I30 WeakPolarHBondContact O-CG1 3.39Å; E26-I30 PolarHBondContact O-N 3.45Å; E26-F275 HydrophobicContact CB-CB 4.47Å; E26-F275 HydrophobicContact CB-CD2 3.93Å; E26-F275 HydrophobicContact CB-CE2 4.2Å; E26-F275 HydrophobicContact CB-CG 4.1Å; E26-F275 HydrophobicContact CG-CB 4.44Å; E26-F275 HydrophobicContact CG-CD1 3.8Å; E26-F275 HydrophobicContact CG-CD2 4.05Å; E26-F275 HydrophobicContact CG-CE1 3.95Å; E26-F275 HydrophobicContact CG-CE2 4.17Å; E26-F275 HydrophobicContact CG-CG 3.87Å; E26-F275 HydrophobicContact CG-CZ 4.12Å
27K94.6Very high90Very high12 Ų1250.4 Ų50.45%0.05228%0.281CS..Hα-helixtrans-57.5-46175.4-64.4-170.1175-164.80112.5L11 E15 F22 S23 I24 A29 I30 A31 A56 I60L11-K27 HydrophobicContact CD2-CB 4.09Å; L11-K27 HydrophobicContact CD2-CG 4.09Å; E15-K27 VanDerWaalsContact CD-CE 3.49Å; E15-K27 VanDerWaalsContact CD-NZ 3.3Å; E15-K27 WeakPolarHBondContact OE1-CE 3.25Å; E15-K27 IonicContact OE1-NZ 2.74Å; E15-K27 PolarHBondContact OE1-NZ 3.34Å; E15-K27 VanDerWaalsContact OE2-CE 3.27Å; E15-K27 WeakPolarHBondContact OE2-CE 3.44Å; E15-K27 IonicContact OE2-NZ 2.81Å; E15-K27 PolarHBondContact OE2-NZ 2.84Å; F22-K27 HydrophobicContact CB-CD 4.39Å; F22-K27 HydrophobicContact CB-CG 3.55Å; F22-K27 HydrophobicContact CG-CG 4.49Å; F22-K27 WeakPolarHBondContact O-CE 3.23Å; S23-K27 WeakPolarHBondContact O-CG 3.37Å; S23-K27 PolarHBondContact O-N 3.33Å; I24-K27 PolarHBondContact O-N 2.53Å; K27-A29 VanDerWaalsContact C-N 3.34Å; K27-A29 PolarHBondContact O-N 2.98Å; K27-I30 PolarHBondContact O-N 3.37Å; K27-A31 WeakPolarHBondContact O-CB 3.18Å; K27-A31 PolarHBondContact O-N 3.21Å; K27-A56 HydrophobicContact CD-CB 3.76Å; K27-I60 HydrophobicContact CB-CD1 4.2Å
28V91.4Very high90.5Very high18 Ų1850.3 Ų50.311%0.10928%0.284CS..Hα-helixtrans-64.4-38.1175.8170.90000111.8I24 K25 E26 A31 K32 Q59 I60 V63I24-V28 WeakPolarHBondContact O-CG2 3.14Å; I24-V28 PolarHBondContact O-N 3.37Å; K25-V28 PolarHBondContact O-N 3.27Å; E26-V28 PolarHBondContact O-N 3.27Å; V28-A31 PolarHBondContact O-N 3.07Å; V28-K32 HydrophobicContact CG1-CD 4.47Å; V28-K32 WeakPolarHBondContact O-CG 3.11Å; V28-K32 PolarHBondContact O-N 2.64Å; V28-K32 VanDerWaalsContact O-N 3.12Å; V28-Q59 HydrophobicContact CG2-CB 3.93Å; V28-I60 HydrophobicContact CG2-CG1 4.13Å; V28-V63 HydrophobicContact CG1-CG2 4.1Å
29A88.5Confident91.3Very high37 Ų3745 Ų4531%0.30625%0.249SC..Hα-helixtrans-66.8-43.217700000112.1K25 E26 K27 K32 R33 F275K25-A29 WeakPolarHBondContact O-CB 3.4Å; K25-A29 PolarHBondContact O-N 3.43Å; E26-A29 WeakPolarHBondContact O-CB 3.37Å; E26-A29 PolarHBondContact O-N 3.12Å; E26-A29 VanDerWaalsContact O-N 3.1Å; K27-A29 VanDerWaalsContact C-N 3.34Å; K27-A29 PolarHBondContact O-N 2.98Å; A29-K32 PolarHBondContact O-N 3.04Å; A29-R33 PolarHBondContact O-N 3.4Å; A29-R33 VanDerWaalsContact O-N 3.07Å; A29-F275 HydrophobicContact CB-CE2 3.97Å; A29-F275 HydrophobicContact CB-CZ 4.44Å
30I92.5Very high92.1Very high0 Ų042.5 Ų42.50%022%0.22CC..Hα-helixtrans-61.1-48.2173.3-68.4166000109.8L11 F22 E26 K27 K32 R33 L34 I272 F275L11-I30 HydrophobicContact CD1-CG2 4.47Å; L11-I30 HydrophobicContact CD2-CB 3.89Å; L11-I30 HydrophobicContact CD2-CD1 3.93Å; L11-I30 HydrophobicContact CD2-CG2 3.66Å; L11-I30 HydrophobicContact CG-CG2 4.14Å; F22-I30 HydrophobicContact CD1-CD1 3.82Å; F22-I30 HydrophobicContact CD2-CD1 4.49Å; F22-I30 HydrophobicContact CE1-CD1 3.73Å; F22-I30 HydrophobicContact CE2-CD1 4.43Å; F22-I30 HydrophobicContact CG-CD1 4.19Å; F22-I30 HydrophobicContact CZ-CD1 4.06Å; E26-I30 VanDerWaalsContact O-CG1 3.31Å; E26-I30 WeakPolarHBondContact O-CG1 3.39Å; E26-I30 PolarHBondContact O-N 3.45Å; K27-I30 PolarHBondContact O-N 3.37Å; I30-K32 VanDerWaalsContact C-N 3.33Å; I30-K32 PolarHBondContact O-N 3.3Å; I30-R33 CarbonylContact O-C 3.54Å; I30-R33 WeakPolarHBondContact O-CA 3.5Å; I30-R33 VanDerWaalsContact O-CB 3.32Å; I30-R33 WeakPolarHBondContact O-CB 3.33Å; I30-R33 PolarHBondContact O-N 3.15Å; I30-L34 HydrophobicContact CG2-CD1 3.68Å; I30-L34 HydrophobicContact CG2-CG 4.08Å; I30-L34 WeakPolarHBondContact O-CG 3.32Å; I30-L34 PolarHBondContact O-N 2.84Å; I30-I272 HydrophobicContact CD1-CG1 4.43Å; I30-I272 HydrophobicContact CG1-CG1 4.18Å; I30-I272 HydrophobicContact CG2-CD1 4.13Å; I30-I272 HydrophobicContact CG2-CG1 4.13Å; I30-F275 HydrophobicContact CD1-CB 4.41Å; I30-F275 HydrophobicContact CD1-CD2 3.94Å; I30-F275 HydrophobicContact CG1-CD2 3.75Å; I30-F275 HydrophobicContact CG1-CE2 4.29Å
31A97.2Very high92.8Very high0 Ų042 Ų420%022%0.217CC..Hα-helixtrans-56.9-44.4179.900000112.6L11 K27 V28 R33 L34 E35 I42 I60 M64L11-A31 HydrophobicContact CD1-CB 4.05Å; K27-A31 WeakPolarHBondContact O-CB 3.18Å; K27-A31 PolarHBondContact O-N 3.21Å; V28-A31 PolarHBondContact O-N 3.07Å; A31-R33 VanDerWaalsContact C-N 3.3Å; A31-R33 PolarHBondContact O-N 2.92Å; A31-L34 PolarHBondContact O-N 3.17Å; A31-E35 PolarHBondContact O-N 2.99Å; A31-I42 HydrophobicContact CB-CD1 4.14Å; A31-I60 HydrophobicContact CB-CD1 4.45Å; A31-I60 HydrophobicContact CB-CG1 4.05Å; A31-I60 HydrophobicContact CB-CG2 3.84Å; A31-M64 HydrophobicContact CB-CE 3.84Å; A31-M64 HydrophobicContact CB-SD 4.11Å
32K94.5Very high93.4Very high111 Ų11135.7 Ų35.748%0.48318%0.183SC..Hα-helixtrans-63.5-35.7174.5-71.6176.9179.2-178.20112.7V28 A29 I30 K36 M64V28-K32 HydrophobicContact CG1-CD 4.47Å; V28-K32 WeakPolarHBondContact O-CG 3.11Å; V28-K32 PolarHBondContact O-N 2.64Å; V28-K32 VanDerWaalsContact O-N 3.12Å; A29-K32 PolarHBondContact O-N 3.04Å; I30-K32 VanDerWaalsContact C-N 3.33Å; I30-K32 PolarHBondContact O-N 3.3Å; K32-K36 PolarHBondContact O-N 3.27Å; K32-K36 VanDerWaalsContact O-N 3.12Å; K32-M64 HydrophobicContact CG-CE 3.88Å
33R94.9Very high94Very high38 Ų3835.4 Ų35.414%0.14318%0.182CC..Hα-helixtrans-67.6-42.2176.3-175.171-168.115616.5111.3A29 I30 A31 K36 W37 E264 T268 L271A29-R33 PolarHBondContact O-N 3.4Å; A29-R33 VanDerWaalsContact O-N 3.07Å; I30-R33 CarbonylContact O-C 3.54Å; I30-R33 WeakPolarHBondContact O-CA 3.5Å; I30-R33 VanDerWaalsContact O-CB 3.32Å; I30-R33 WeakPolarHBondContact O-CB 3.33Å; I30-R33 PolarHBondContact O-N 3.15Å; A31-R33 VanDerWaalsContact C-N 3.3Å; A31-R33 PolarHBondContact O-N 2.92Å; R33-K36 WeakPolarHBondContact O-CB 3.22Å; R33-K36 PolarHBondContact O-N 2.91Å; R33-W37 WeakPolarHBondContact O-CB 3.42Å; R33-W37 PolarHBondContact O-N 3.31Å; R33-E264 IonicContact CZ-OE2 2.75Å; R33-E264 IonicContact NH1-OE2 3.33Å; R33-E264 PolarHBondContact NH1-OE2 2.92Å; R33-E264 VanDerWaalsContact NH2-CB 3.35Å; R33-E264 PolarHBondContact NH2-O 3.49Å; R33-E264 IonicContact NH2-OE2 3.2Å; R33-E264 PolarHBondContact NH2-OE2 3.09Å; R33-T268 HydrophobicContact CG-CG2 3.92Å; R33-T268 WeakPolarHBondContact CG-OG1 3.37Å; R33-T268 PolarHBondContact NE-OG1 3.36Å; R33-T268 PolarHBondContact NH2-OG1 3.48Å; R33-L271 HydrophobicContact CB-CD2 3.59Å; R33-L271 HydrophobicContact CG-CD2 3.67Å
34L98.1Very high94.7Very high0 Ų032.9 Ų32.90%016%0.164CC..Hα-helixtrans-64.3-43.2176.4-67.9170.1000111.7D8 I30 A31 K36 W37 G38 I39 I42 V228 T268 I272D8-L34 HydrophobicContact CB-CD1 4.02Å; D8-L34 HydrophobicContact CB-CD2 4.22Å; D8-L34 VanDerWaalsContact CG-CD1 3.49Å; D8-L34 WeakPolarHBondContact OD1-CD1 3.35Å; I30-L34 HydrophobicContact CG2-CD1 3.68Å; I30-L34 HydrophobicContact CG2-CG 4.08Å; I30-L34 WeakPolarHBondContact O-CG 3.32Å; I30-L34 PolarHBondContact O-N 2.84Å; A31-L34 PolarHBondContact O-N 3.17Å; L34-K36 VanDerWaalsContact C-N 3.32Å; L34-K36 PolarHBondContact O-N 3.16Å; L34-W37 HydrophobicContact CD2-CE3 4.14Å; L34-W37 PolarHBondContact O-N 3.02Å; L34-W37 VanDerWaalsContact O-N 3.12Å; L34-G38 PolarHBondContact O-N 3.33Å; L34-I39 HydrophobicContact CB-CB 4.2Å; L34-I39 HydrophobicContact CB-CG1 3.92Å; L34-I39 HydrophobicContact CD2-CG1 4.01Å; L34-I39 WeakPolarHBondContact O-CB 3.48Å; L34-I39 WeakPolarHBondContact O-CG1 3.47Å; L34-I39 PolarHBondContact O-N 2.94Å; L34-I39 VanDerWaalsContact O-N 3.12Å; L34-I42 HydrophobicContact CB-CD1 3.81Å; L34-I42 HydrophobicContact CB-CG1 4.24Å; L34-I42 HydrophobicContact CD1-CD1 4.15Å; L34-I42 HydrophobicContact CD1-CG1 4.15Å; L34-I42 HydrophobicContact CD1-CG2 4.46Å; L34-V228 HydrophobicContact CD2-CG2 3.88Å; L34-T268 HydrophobicContact CD2-CG2 4.21Å; L34-I272 HydrophobicContact CD2-CD1 4.4Å
35E97.1Very high95Very high34 Ų3430.9 Ų30.916%0.15915%0.154CC..Hα-helixtrans-58.6-44.2172.9177.9166.4-98.600111.1A31 W37 G38 M64 T65 T66 T67A31-E35 PolarHBondContact O-N 2.99Å; E35-W37 VanDerWaalsContact C-N 3.31Å; E35-W37 PolarHBondContact O-N 3.3Å; E35-G38 PolarHBondContact O-N 3.27Å; E35-G38 VanDerWaalsContact O-N 3.15Å; E35-M64 HydrophobicContact CB-SD 4.04Å; E35-T65 PolarHBondContact OE1-N 3.02Å; E35-T65 PolarHBondContact OE2-OG1 3.43Å; E35-T65 VanDerWaalsContact OE2-OG1 3.09Å; E35-T66 WeakPolarHBondContact CG-OG1 3.33Å; E35-T66 PolarHBondContact OE1-N 3.33Å; E35-T66 PolarHBondContact OE1-OG1 3.39Å; E35-T66 VanDerWaalsContact OE1-OG1 3.14Å; E35-T67 WeakPolarHBondContact CA-OG1 3.45Å; E35-T67 WeakPolarHBondContact CB-OG1 3.26Å; E35-T67 WeakPolarHBondContact CG-OG1 3.36Å; E35-T67 PolarHBondContact OE1-N 2.83Å
36K94.9Very high95.5Very high112 Ų11224.2 Ų24.249%0.48713%0.125SC..Hα-helixtrans-63.7-34.6175.3-167.1-171.4-177.3-151.30112.9K32 R33 L34 G38 E264K32-K36 PolarHBondContact O-N 3.27Å; K32-K36 VanDerWaalsContact O-N 3.12Å; R33-K36 WeakPolarHBondContact O-CB 3.22Å; R33-K36 PolarHBondContact O-N 2.91Å; L34-K36 VanDerWaalsContact C-N 3.32Å; L34-K36 PolarHBondContact O-N 3.16Å; K36-G38 PolarHBondContact O-N 3.41Å; K36-E264 WeakPolarHBondContact CE-OE1 3.38Å; K36-E264 WeakPolarHBondContact CE-OE2 3.37Å; K36-E264 IonicContact NZ-OE1 2.75Å; K36-E264 PolarHBondContact NZ-OE1 2.91Å; K36-E264 IonicContact NZ-OE2 2.61Å; K36-E264 PolarHBondContact NZ-OE2 3.45Å
37W97.4Very high96Very high1 Ų121.8 Ų21.80%0.00412%0.115CC..Hα-helixtrans-72.9-13.3178.2-169.636.9000112.8R33 L34 E35 I39 V228 L240 E241 A244 I260 V261 T265 T268R33-W37 WeakPolarHBondContact O-CB 3.42Å; R33-W37 PolarHBondContact O-N 3.31Å; L34-W37 HydrophobicContact CD2-CE3 4.14Å; L34-W37 PolarHBondContact O-N 3.02Å; L34-W37 VanDerWaalsContact O-N 3.12Å; E35-W37 VanDerWaalsContact C-N 3.31Å; E35-W37 PolarHBondContact O-N 3.3Å; W37-I39 HydrophobicContact CE3-CD1 3.78Å; W37-I39 HydrophobicContact CE3-CG1 3.87Å; W37-I39 HydrophobicContact CZ3-CD1 3.86Å; W37-I39 HydrophobicContact CZ3-CG1 4.41Å; W37-V228 HydrophobicContact CE3-CG2 4.22Å; W37-V228 HydrophobicContact CH2-CG2 4.16Å; W37-V228 HydrophobicContact CZ3-CG2 3.55Å; W37-L240 HydrophobicContact CH2-CB 3.78Å; W37-L240 HydrophobicContact CZ3-CB 4.02Å; W37-L240 HydrophobicContact CZ3-CD1 4.42Å; W37-E241 HydrophobicContact CH2-CB 4.24Å; W37-E241 HydrophobicContact CZ2-CB 4.14Å; W37-A244 HydrophobicContact CZ2-CB 4.48Å; W37-I260 HydrophobicContact CD2-CG2 4.26Å; W37-I260 HydrophobicContact CG-CG2 4.38Å; W37-I260 HydrophobicContact CZ2-CG2 4.09Å; W37-I260 CarbonylContact O-C 3.56Å; W37-I260 WeakPolarHBondContact O-CA 3.41Å; W37-V261 PolarHBondContact O-N 3.28Å; W37-T265 HydrophobicContact CZ2-CG2 4.06Å; W37-T265 PolarHBondContact NE1-OG1 2.93Å; W37-T268 HydrophobicContact CD2-CG2 4.24Å; W37-T268 HydrophobicContact CE3-CG2 4.11Å; W37-T268 HydrophobicContact CG-CG2 4.48Å
38G97.9Very high96.1Very high18 Ų1823 Ų2319%0.18613%0.127CC..THydrogen-bonded Turntrans98.720176.600000114.5L34 E35 K36 A40L34-G38 PolarHBondContact O-N 3.33Å; E35-G38 PolarHBondContact O-N 3.27Å; E35-G38 VanDerWaalsContact O-N 3.15Å; K36-G38 PolarHBondContact O-N 3.41Å; G38-A40 PolarHBondContact O-N 3.39Å
39I98.5Very high96.2Very high3 Ų325.4 Ų25.42%0.01515%0.148CC..  trans-64.8130.2175.2-67.1-63000110.4F6 D8 L34 W37 S41 I42 T67 L240 I260F6-I39 HydrophobicContact CB-CD1 3.75Å; D8-I39 HydrophobicContact CB-CD1 4.14Å; D8-I39 HydrophobicContact CB-CG1 4.25Å; D8-I39 HydrophobicContact CB-CG2 3.9Å; L34-I39 HydrophobicContact CB-CB 4.2Å; L34-I39 HydrophobicContact CB-CG1 3.92Å; L34-I39 HydrophobicContact CD2-CG1 4.01Å; L34-I39 WeakPolarHBondContact O-CB 3.48Å; L34-I39 WeakPolarHBondContact O-CG1 3.47Å; L34-I39 PolarHBondContact O-N 2.94Å; L34-I39 VanDerWaalsContact O-N 3.12Å; W37-I39 HydrophobicContact CE3-CD1 3.78Å; W37-I39 HydrophobicContact CE3-CG1 3.87Å; W37-I39 HydrophobicContact CZ3-CD1 3.86Å; W37-I39 HydrophobicContact CZ3-CG1 4.41Å; I39-S41 WeakPolarHBondContact CG2-O 3.49Å; I39-I42 HydrophobicContact CG2-CG1 3.76Å; I39-T67 HydrophobicContact CG2-CG2 4.23Å; I39-T67 WeakPolarHBondContact O-CB 3.31Å; I39-T67 VanDerWaalsContact O-CG2 3.25Å; I39-T67 WeakPolarHBondContact O-CG2 3.35Å; I39-T67 PolarHBondContact O-OG1 3.37Å; I39-L240 HydrophobicContact CD1-CD1 4.1Å; I39-I260 HydrophobicContact CD1-CD1 3.91Å
40A98.4Very high96.5Very high30 Ų3026 Ų2625%0.24815%0.15CC..SBendtrans-79.4-36.5-177.400000112.2E5 F6 G38 A68E5-A40 HydrophobicContact CB-CB 3.99Å; E5-A40 HydrophobicContact CG-CB 4.26Å; F6-A40 PolarHBondContact O-N 2.59Å; G38-A40 PolarHBondContact O-N 3.39Å; A40-A68 PolarHBondContact O-N 3.11Å
41S98.5Very high96.6Very high0 Ų031.2 Ų31.20%018%0.184CC..EExtended strand (participates in β ladder)trans-142.8144.8175.8-166.10000111.6F6 L7 D8 I39 A68 S70 Q94F6-S41 PolarHBondContact O-N 3.04Å; L7-S41 CarbonylContact C-O 3.39Å; L7-S41 WeakPolarHBondContact CA-O 3.3Å; D8-S41 PolarHBondContact N-O 3.11Å; I39-S41 WeakPolarHBondContact CG2-O 3.49Å; S41-A68 CarbonylContact C-O 3.5Å; S41-A68 WeakPolarHBondContact CA-O 3.4Å; S41-S70 PolarHBondContact OG-OG 2.63Å; S41-S70 VanDerWaalsContact OG-OG 3.07Å; S41-Q94 PolarHBondContact OG-OE1 3.36Å
42I98.7Very high96.2Very high0 Ų036.7 Ų36.70%021%0.213CC..EExtended strand (participates in β ladder)trans-117.7122.7174.6-64.4162.6000108.2L11 A31 L34 I39 A44 M64 T67 A68 S70L11-I42 HydrophobicContact CD1-CG2 3.92Å; A31-I42 HydrophobicContact CB-CD1 4.14Å; L34-I42 HydrophobicContact CB-CD1 3.81Å; L34-I42 HydrophobicContact CB-CG1 4.24Å; L34-I42 HydrophobicContact CD1-CD1 4.15Å; L34-I42 HydrophobicContact CD1-CG1 4.15Å; L34-I42 HydrophobicContact CD1-CG2 4.46Å; I39-I42 HydrophobicContact CG2-CG1 3.76Å; I42-A44 HydrophobicContact CG2-CB 4.42Å; I42-A44 PolarHBondContact O-N 2.92Å; I42-A44 VanDerWaalsContact O-N 3.12Å; I42-M64 HydrophobicContact CD1-SD 3.91Å; I42-T67 HydrophobicContact CB-CG2 4.42Å; I42-T67 HydrophobicContact CD1-CG2 3.63Å; I42-T67 HydrophobicContact CG1-CG2 3.64Å; I42-A68 PolarHBondContact N-O 2.96Å; I42-S70 PolarHBondContact O-N 3.14Å
43E98.5Very high96.2Very high0 Ų032.1 Ų32.10%020%0.195CC..EExtended strand (participates in β ladder)trans-77.493.4164.9-170.7173.274.700109L7 D8 T9 R12 G45 S70 H96L7-E43 HydrophobicContact CD2-CB 3.94Å; D8-E43 PolarHBondContact O-N 3.47Å; T9-E43 HydrophobicContact CG2-CB 4.03Å; R12-E43 HydrophobicContact CB-CG 4.01Å; R12-E43 HydrophobicContact CG-CG 4.29Å; R12-E43 IonicContact CZ-OE1 3.81Å; R12-E43 IonicContact NE-OE1 3.58Å; R12-E43 PolarHBondContact NE-OE1 2.87Å; R12-E43 IonicContact NH2-OE1 3.12Å; R12-E43 PolarHBondContact NH2-OE1 3.25Å; E43-G45 PolarHBondContact O-N 3.49Å; E43-S70 WeakPolarHBondContact CA-O 3.49Å; E43-H96 IonicContact OE2-CE1 3.97Å; E43-H96 IonicContact OE2-CG 2.74Å; E43-H96 IonicContact OE2-ND1 3.74Å; E43-H96 PolarHBondContact OE2-ND1 2.87Å
44A97.1Very high96.3Very high0 Ų033.1 Ų33.10%020%0.201CC..EExtended strand (participates in β ladder)trans-77-7.9-166.300000114.1I42 V57 I60 V69 S70I42-A44 HydrophobicContact CG2-CB 4.42Å; I42-A44 PolarHBondContact O-N 2.92Å; I42-A44 VanDerWaalsContact O-N 3.12Å; A44-V57 HydrophobicContact CB-CB 4.48Å; A44-V57 HydrophobicContact CB-CG1 4.43Å; A44-V57 HydrophobicContact CB-CG2 3.94Å; A44-I60 HydrophobicContact CB-CB 4.29Å; A44-I60 HydrophobicContact CB-CD1 3.8Å; A44-I60 HydrophobicContact CB-CG2 4.03Å; A44-V69 HydrophobicContact CB-CG1 3.64Å; A44-S70 PolarHBondContact N-O 2.98Å
45G95.1Very high96.3Very high2 Ų235.2 Ų35.22%0.02121%0.21CC..EExtended strand (participates in β ladder)trans151.2-168.8179.400000113.2E43 P47 L72E43-G45 PolarHBondContact O-N 3.49Å; G45-P47 WeakPolarHBondContact O-CD 3.4Å; G45-L72 PolarHBondContact O-N 2.96Å; G45-L72 VanDerWaalsContact O-N 3.17Å
46F96Very high96.2Very high38 Ų3833.6 Ų33.617%0.16720%0.203CC..  trans-116.292.1173-174.2175.5000108.7A48 A49 S53 L72 R74 D79F46-A48 HydrophobicContact CD2-CB 4.14Å; F46-A48 HydrophobicContact CE2-CB 3.68Å; F46-A48 PolarHBondContact O-N 2.78Å; F46-A48 VanDerWaalsContact O-N 3.09Å; F46-A49 HydrophobicContact CB-CB 3.99Å; F46-A49 HydrophobicContact CD1-CB 4.04Å; F46-A49 HydrophobicContact CG-CB 3.93Å; F46-A49 VanDerWaalsContact O-CB 3.25Å; F46-A49 WeakPolarHBondContact O-CB 3.42Å; F46-A49 PolarHBondContact O-N 3.35Å; F46-S53 PolarHBondContact N-OG 3.24Å; F46-S53 WeakPolarHBondContact O-CB 3.29Å; F46-S53 PolarHBondContact O-OG 3.49Å; F46-L72 HydrophobicContact CB-CB 4.43Å; F46-L72 HydrophobicContact CD1-CD2 4.39Å; F46-L72 WeakPolarHBondContact CD2-O 3.38Å; F46-L72 WeakPolarHBondContact CE2-O 3.41Å; F46-R74 HydrophobicContact CE1-CG 4.28Å; F46-R74 HydrophobicContact CZ-CG 3.79Å; F46-D79 HydrophobicContact CE2-CB 4.35Å; F46-D79 WeakPolarHBondContact CE2-OD2 3.41Å; F46-D79 VanDerWaalsContact CZ-OD2 3.24Å; F46-D79 WeakPolarHBondContact CZ-OD2 3.24Å
47P96.6Very high96.4Very high4 Ų428.3 Ų28.33%0.02618%0.18CC..THydrogen-bonded Turntrans-53.8-33.2-172-31.637.5000115.2G45 A49 F54 V57 A82 C83 A86G45-P47 WeakPolarHBondContact O-CD 3.4Å; P47-A49 VanDerWaalsContact C-N 3.31Å; P47-A49 PolarHBondContact O-N 2.88Å; P47-F54 HydrophobicContact CB-CD2 4.18Å; P47-V57 HydrophobicContact CG-CB 4.21Å; P47-V57 HydrophobicContact CG-CG1 4.08Å; P47-V57 HydrophobicContact CG-CG2 4Å; P47-A82 HydrophobicContact CB-CB 4.18Å; P47-C83 HydrophobicContact CG-CB 4.47Å; P47-A86 HydrophobicContact CB-CB 3.98Å; P47-A86 HydrophobicContact CG-CB 4.05Å
48A97Very high96.4Very high37 Ų3733.4 Ų33.431%0.30620%0.199SC..THydrogen-bonded Turntrans-80.1-9.2-179.700000114.2F46 D79 A82F46-A48 HydrophobicContact CD2-CB 4.14Å; F46-A48 HydrophobicContact CE2-CB 3.68Å; F46-A48 PolarHBondContact O-N 2.78Å; F46-A48 VanDerWaalsContact O-N 3.09Å; A48-D79 HydrophobicContact CB-CB 3.98Å; A48-A82 HydrophobicContact CB-CB 3.97Å
49A93.8Very high96.4Very high68 Ų6836.1 Ų36.156%0.56221%0.207SC*.THydrogen-bonded Turntrans-74-39.5-174.900000113F46 P47F46-A49 HydrophobicContact CB-CB 3.99Å; F46-A49 HydrophobicContact CD1-CB 4.04Å; F46-A49 HydrophobicContact CG-CB 3.93Å; F46-A49 VanDerWaalsContact O-CB 3.25Å; F46-A49 WeakPolarHBondContact O-CB 3.42Å; F46-A49 PolarHBondContact O-N 3.35Å; P47-A49 VanDerWaalsContact C-N 3.31Å; P47-A49 PolarHBondContact O-N 2.88Å
50S93.2Very high96.3Very high49 Ų4936 Ų3634%0.34321%0.207SC..  trans-160.6158.5179.171.40000111.8D52 S53 F54S50-D52 PolarHBondContact O-N 3.19Å; S50-S53 WeakPolarHBondContact O-CB 3.39Å; S50-S53 PolarHBondContact O-N 3.3Å; S50-S53 WeakPolarHBondContact OG-CB 3.16Å; S50-S53 PolarHBondContact OG-N 3.46Å; S50-F54 PolarHBondContact O-N 2.99Å
51P94.4Very high96.3Very high110 Ų11034.6 Ų34.671%0.71420%0.195SC*.Hα-helixtrans-56.3-36.2172-2635.6000113.5F54 E55P51-F54 WeakPolarHBondContact O-CB 3.29Å; P51-F54 PolarHBondContact O-N 3.28Å; P51-E55 WeakPolarHBondContact O-CB 3.4Å; P51-E55 PolarHBondContact O-N 2.91Å
52D90.7Very high96.2Very high116 Ų11637.6 Ų37.662%0.6222%0.22SC*.Hα-helixtrans-68.4-38.9178.1-67.5-19.3000111.8S50 E55 A56S50-D52 PolarHBondContact O-N 3.19Å; D52-E55 PolarHBondContact O-N 3.41Å; D52-A56 WeakPolarHBondContact O-CB 3.24Å; D52-A56 PolarHBondContact O-N 3.24Å
53S93.8Very high96.1Very high14 Ų1439.9 Ų39.910%0.09823%0.234CC..Hα-helixtrans-64.9-43.2174-175.60000111.2F46 S50 A56 V57F46-S53 PolarHBondContact N-OG 3.24Å; F46-S53 WeakPolarHBondContact O-CB 3.29Å; F46-S53 PolarHBondContact O-OG 3.49Å; S50-S53 WeakPolarHBondContact O-CB 3.39Å; S50-S53 PolarHBondContact O-N 3.3Å; S50-S53 WeakPolarHBondContact OG-CB 3.16Å; S50-S53 PolarHBondContact OG-N 3.46Å; S53-A56 PolarHBondContact O-N 3.38Å; S53-V57 WeakPolarHBondContact O-CG2 3.46Å; S53-V57 PolarHBondContact O-N 3.38Å
54F97.7Very high96Very high59 Ų5940.3 Ų40.326%0.25924%0.236SC..Hα-helixtrans-58.2-49173.7-175.3-83.5000111.8P47 S50 P51 V57 R58 A82 E85 A86P47-F54 HydrophobicContact CB-CD2 4.18Å; S50-F54 PolarHBondContact O-N 2.99Å; P51-F54 WeakPolarHBondContact O-CB 3.29Å; P51-F54 PolarHBondContact O-N 3.28Å; F54-V57 PolarHBondContact O-N 3.15Å; F54-R58 WeakPolarHBondContact O-CB 3.22Å; F54-R58 PolarHBondContact O-N 2.73Å; F54-A82 WeakPolarHBondContact CE2-O 3.44Å; F54-E85 HydrophobicContact CE2-CB 3.9Å; F54-E85 HydrophobicContact CZ-CB 3.89Å; F54-A86 HydrophobicContact CD2-CB 3.88Å; F54-A86 HydrophobicContact CE2-CB 3.73Å; F54-A86 HydrophobicContact CG-CB 4.38Å; F54-A86 HydrophobicContact CZ-CB 4.09Å
55E97.5Very high96Very high44 Ų4443.9 Ų43.921%0.20626%0.258CS..Hα-helixtrans-65.4-39.3180-177.658.6-156.700112.1I24 P51 D52 R58 Q59I24-E55 HydrophobicContact CD1-CB 4.18Å; I24-E55 HydrophobicContact CD1-CG 3.89Å; P51-E55 WeakPolarHBondContact O-CB 3.4Å; P51-E55 PolarHBondContact O-N 2.91Å; D52-E55 PolarHBondContact O-N 3.41Å; E55-R58 PolarHBondContact O-N 3.08Å; E55-R58 IonicContact OE1-CZ 3.78Å; E55-R58 IonicContact OE1-NE 3.15Å; E55-R58 IonicContact OE1-NH2 3.7Å; E55-R58 PolarHBondContact OE1-NH2 3.32Å; E55-R58 IonicContact OE2-CZ 3.38Å; E55-R58 IonicContact OE2-NE 3.54Å; E55-R58 PolarHBondContact OE2-NE 2.83Å; E55-R58 VanDerWaalsContact OE2-NE 3.12Å; E55-R58 IonicContact OE2-NH1 3.76Å; E55-R58 IonicContact OE2-NH2 2.75Å; E55-R58 PolarHBondContact OE2-NH2 3.19Å; E55-Q59 WeakPolarHBondContact O-CG 3.49Å; E55-Q59 PolarHBondContact O-N 3.23Å; E55-Q59 WeakPolarHBondContact OE1-CG 3.2Å; E55-Q59 PolarHBondContact OE1-NE2 3Å
56A94.7Very high96.1Very high1 Ų148.4 Ų48.41%0.00829%0.285CS..Hα-helixtrans-59.8-49.2175.600000111.6I24 K27 D52 S53 R58 Q59 I60I24-A56 HydrophobicContact CG1-CB 4.27Å; K27-A56 HydrophobicContact CD-CB 3.76Å; D52-A56 WeakPolarHBondContact O-CB 3.24Å; D52-A56 PolarHBondContact O-N 3.24Å; S53-A56 PolarHBondContact O-N 3.38Å; A56-R58 VanDerWaalsContact C-N 3.32Å; A56-R58 PolarHBondContact O-N 3.02Å; A56-Q59 PolarHBondContact O-N 2.87Å; A56-I60 WeakPolarHBondContact O-CD1 3.46Å; A56-I60 VanDerWaalsContact O-CG1 3.31Å; A56-I60 WeakPolarHBondContact O-CG1 3.46Å; A56-I60 PolarHBondContact O-N 3.28Å
57V98.1Very high96.2Very high0 Ų046.9 Ų46.90%028%0.279CS..Hα-helixtrans-62-41.1177.9174.10000110.8A44 P47 S53 F54 I60 S61 A86 L87A44-V57 HydrophobicContact CB-CB 4.48Å; A44-V57 HydrophobicContact CB-CG1 4.43Å; A44-V57 HydrophobicContact CB-CG2 3.94Å; P47-V57 HydrophobicContact CG-CB 4.21Å; P47-V57 HydrophobicContact CG-CG1 4.08Å; P47-V57 HydrophobicContact CG-CG2 4Å; S53-V57 WeakPolarHBondContact O-CG2 3.46Å; S53-V57 PolarHBondContact O-N 3.38Å; F54-V57 PolarHBondContact O-N 3.15Å; V57-I60 PolarHBondContact O-N 2.98Å; V57-S61 VanDerWaalsContact O-CB 3.26Å; V57-S61 WeakPolarHBondContact O-CB 3.33Å; V57-S61 PolarHBondContact O-N 2.97Å; V57-S61 PolarHBondContact O-OG 3.36Å; V57-A86 HydrophobicContact CB-CB 4.14Å; V57-A86 HydrophobicContact CG1-CB 3.79Å; V57-L87 HydrophobicContact CG1-CD2 3.55Å; V57-L87 HydrophobicContact CG1-CG 4.12Å
58R98.2Very high96.3Very high109 Ų10947 Ų4741%0.41128%0.28SS..Hα-helixtrans-61.2-46.1175.8-168.9-174.973.7168.42.3112.5F54 E55 A56 S61 A62 A86F54-R58 WeakPolarHBondContact O-CB 3.22Å; F54-R58 PolarHBondContact O-N 2.73Å; E55-R58 PolarHBondContact O-N 3.08Å; E55-R58 IonicContact OE1-CZ 3.78Å; E55-R58 IonicContact OE1-NE 3.15Å; E55-R58 IonicContact OE1-NH2 3.7Å; E55-R58 PolarHBondContact OE1-NH2 3.32Å; E55-R58 IonicContact OE2-CZ 3.38Å; E55-R58 IonicContact OE2-NE 3.54Å; E55-R58 PolarHBondContact OE2-NE 2.83Å; E55-R58 VanDerWaalsContact OE2-NE 3.12Å; E55-R58 IonicContact OE2-NH1 3.76Å; E55-R58 IonicContact OE2-NH2 2.75Å; E55-R58 PolarHBondContact OE2-NH2 3.19Å; A56-R58 VanDerWaalsContact C-N 3.32Å; A56-R58 PolarHBondContact O-N 3.02Å; R58-S61 WeakPolarHBondContact O-CB 3.41Å; R58-S61 PolarHBondContact O-N 3.28Å; R58-A62 PolarHBondContact O-N 3.28Å; R58-A62 VanDerWaalsContact O-N 3.13Å; R58-A86 WeakPolarHBondContact CA-O 3.31Å
59Q97.6Very high96.3Very high75 Ų7545.2 Ų45.235%0.3527%0.266SS..Hα-helixtrans-67.8-38.7179.6-71.6-168.931.300112.6I24 V28 E55 A56 A62 V63I24-Q59 HydrophobicContact CG2-CB 4.43Å; I24-Q59 HydrophobicContact CG2-CG 4.41Å; V28-Q59 HydrophobicContact CG2-CB 3.93Å; E55-Q59 WeakPolarHBondContact O-CG 3.49Å; E55-Q59 PolarHBondContact O-N 3.23Å; E55-Q59 WeakPolarHBondContact OE1-CG 3.2Å; E55-Q59 PolarHBondContact OE1-NE2 3Å; A56-Q59 PolarHBondContact O-N 2.87Å; Q59-A62 PolarHBondContact O-N 3.5Å; Q59-V63 WeakPolarHBondContact O-CG2 3.49Å; Q59-V63 PolarHBondContact O-N 3.11Å
60I97.4Very high96.6Very high0 Ų042 Ų420%024%0.239CC..Hα-helixtrans-63.4-46.5174.3-68.8162.2000110.1L11 K27 V28 A31 A44 A56 V57 A62 V63 M64 V69L11-I60 HydrophobicContact CD1-CD1 3.64Å; K27-I60 HydrophobicContact CB-CD1 4.2Å; V28-I60 HydrophobicContact CG2-CG1 4.13Å; A31-I60 HydrophobicContact CB-CD1 4.45Å; A31-I60 HydrophobicContact CB-CG1 4.05Å; A31-I60 HydrophobicContact CB-CG2 3.84Å; A44-I60 HydrophobicContact CB-CB 4.29Å; A44-I60 HydrophobicContact CB-CD1 3.8Å; A44-I60 HydrophobicContact CB-CG2 4.03Å; A56-I60 WeakPolarHBondContact O-CD1 3.46Å; A56-I60 VanDerWaalsContact O-CG1 3.31Å; A56-I60 WeakPolarHBondContact O-CG1 3.46Å; A56-I60 PolarHBondContact O-N 3.28Å; V57-I60 PolarHBondContact O-N 2.98Å; I60-A62 VanDerWaalsContact C-N 3.26Å; I60-A62 PolarHBondContact O-N 3.5Å; I60-V63 VanDerWaalsContact O-CG2 3.27Å; I60-V63 WeakPolarHBondContact O-CG2 3.01Å; I60-V63 PolarHBondContact O-N 3.4Å; I60-M64 HydrophobicContact CG2-CG 3.88Å; I60-M64 WeakPolarHBondContact O-CG 3.37Å; I60-M64 PolarHBondContact O-N 3.09Å; I60-M64 VanDerWaalsContact O-N 3.14Å; I60-V69 HydrophobicContact CG2-CG1 4.17Å; I60-V69 HydrophobicContact CG2-CG2 4.3Å
61S97.8Very high96.8Very high0 Ų039.7 Ų39.70%022%0.223CC..Hα-helixtrans-52.4-44.3177.2-63.90000112.5V57 R58 V63 A86 L87 A90V57-S61 VanDerWaalsContact O-CB 3.26Å; V57-S61 WeakPolarHBondContact O-CB 3.33Å; V57-S61 PolarHBondContact O-N 2.97Å; V57-S61 PolarHBondContact O-OG 3.36Å; R58-S61 WeakPolarHBondContact O-CB 3.41Å; R58-S61 PolarHBondContact O-N 3.28Å; S61-V63 VanDerWaalsContact C-N 3.29Å; S61-V63 PolarHBondContact O-N 3.1Å; S61-A86 PolarHBondContact OG-O 2.85Å; S61-L87 WeakPolarHBondContact OG-CD2 3.34Å; S61-A90 WeakPolarHBondContact O-CA 3.48Å
62A97.3Very high97Very high64 Ų6435 Ų3553%0.52919%0.192SC..Hα-helixtrans-71-18.1-178.700000114.7R58 Q59 I60 D89R58-A62 PolarHBondContact O-N 3.28Å; R58-A62 VanDerWaalsContact O-N 3.13Å; Q59-A62 PolarHBondContact O-N 3.5Å; I60-A62 VanDerWaalsContact C-N 3.26Å; I60-A62 PolarHBondContact O-N 3.5Å; A62-D89 HydrophobicContact CB-CB 4.23Å
63V95.7Very high97.3Very high47 Ų4729.5 Ų29.529%0.28516%0.162SC..Hα-helixtrans-107.9-17.9-175.5-60.80000114.8V28 Q59 I60 S61V28-V63 HydrophobicContact CG1-CG2 4.1Å; Q59-V63 WeakPolarHBondContact O-CG2 3.49Å; Q59-V63 PolarHBondContact O-N 3.11Å; I60-V63 VanDerWaalsContact O-CG2 3.27Å; I60-V63 WeakPolarHBondContact O-CG2 3.01Å; I60-V63 PolarHBondContact O-N 3.4Å; S61-V63 VanDerWaalsContact C-N 3.29Å; S61-V63 PolarHBondContact O-N 3.1Å
64M97.3Very high97.5Very high9 Ų934.6 Ų34.64%0.04418%0.179CC..  trans-75.6138.4178.9-65.3-62.394.500110.9A31 K32 E35 I42 I60 V69A31-M64 HydrophobicContact CB-CE 3.84Å; A31-M64 HydrophobicContact CB-SD 4.11Å; K32-M64 HydrophobicContact CG-CE 3.88Å; E35-M64 HydrophobicContact CB-SD 4.04Å; I42-M64 HydrophobicContact CD1-SD 3.91Å; I60-M64 HydrophobicContact CG2-CG 3.88Å; I60-M64 WeakPolarHBondContact O-CG 3.37Å; I60-M64 PolarHBondContact O-N 3.09Å; I60-M64 VanDerWaalsContact O-N 3.14Å; M64-V69 HydrophobicContact CB-CG2 3.89Å; M64-V69 HydrophobicContact CG-CG2 3.7Å
65T96.4Very high97.5Very high75 Ų7532.4 Ų32.446%0.4617%0.171SC..SBendtrans-123.7-27.8-170.7630000114.1E35 K91E35-T65 PolarHBondContact OE1-N 3.02Å; E35-T65 PolarHBondContact OE2-OG1 3.43Å; E35-T65 VanDerWaalsContact OE2-OG1 3.09Å; T65-K91 VanDerWaalsContact O-CD 3.29Å; T65-K91 WeakPolarHBondContact O-CD 2.96Å; T65-K91 PolarHBondContact O-NZ 2.92Å
66T96.5Very high97.5Very high98 Ų9833.1 Ų33.160%0.60118%0.178SC*.SBendtrans-127.2-30.7179.652.90000112.1E35E35-T66 WeakPolarHBondContact CG-OG1 3.33Å; E35-T66 PolarHBondContact OE1-N 3.33Å; E35-T66 PolarHBondContact OE1-OG1 3.39Å; E35-T66 VanDerWaalsContact OE1-OG1 3.14Å
67T98.1Very high97.7Very high5 Ų537.2 Ų37.23%0.03120%0.196CC..SBendtrans-85138.1179.3-62.30000111E35 I39 I42E35-T67 WeakPolarHBondContact CA-OG1 3.45Å; E35-T67 WeakPolarHBondContact CB-OG1 3.26Å; E35-T67 WeakPolarHBondContact CG-OG1 3.36Å; E35-T67 PolarHBondContact OE1-N 2.83Å; I39-T67 HydrophobicContact CG2-CG2 4.23Å; I39-T67 WeakPolarHBondContact O-CB 3.31Å; I39-T67 VanDerWaalsContact O-CG2 3.25Å; I39-T67 WeakPolarHBondContact O-CG2 3.35Å; I39-T67 PolarHBondContact O-OG1 3.37Å; I42-T67 HydrophobicContact CB-CG2 4.42Å; I42-T67 HydrophobicContact CD1-CG2 3.63Å; I42-T67 HydrophobicContact CG1-CG2 3.64Å
68A98.5Very high97.7Very high6 Ų640.8 Ų40.85%0.0522%0.221CC..EExtended strand (participates in β ladder)trans-74.3154.3173.500000112A40 S41 I42 Y92 Q94A40-A68 PolarHBondContact O-N 3.11Å; S41-A68 CarbonylContact C-O 3.5Å; S41-A68 WeakPolarHBondContact CA-O 3.4Å; I42-A68 PolarHBondContact N-O 2.96Å; A68-Y92 CarbonylContact C-O 3.48Å; A68-Y92 VanDerWaalsContact CA-O 3.28Å; A68-Y92 WeakPolarHBondContact CA-O 3.42Å; A68-Y92 WeakPolarHBondContact CB-O 3.39Å; A68-Q94 HydrophobicContact CB-CG 4.15Å
69V98.6Very high97.7Very high1 Ų135.8 Ų35.81%0.00620%0.203CC..EExtended strand (participates in β ladder)trans-120.2116.4179.5-169.60000108.9A44 I60 M64 L87 A90 Y92 Q94A44-V69 HydrophobicContact CB-CG1 3.64Å; I60-V69 HydrophobicContact CG2-CG1 4.17Å; I60-V69 HydrophobicContact CG2-CG2 4.3Å; M64-V69 HydrophobicContact CB-CG2 3.89Å; M64-V69 HydrophobicContact CG-CG2 3.7Å; V69-L87 HydrophobicContact CB-CD2 3.93Å; V69-L87 HydrophobicContact CG1-CD2 3.53Å; V69-A90 HydrophobicContact CB-CB 4.14Å; V69-A90 HydrophobicContact CG2-CB 4.3Å; V69-Y92 PolarHBondContact N-O 3.5Å; V69-Q94 PolarHBondContact O-N 3.49Å
70S98.5Very high97.7Very high0 Ų032.2 Ų32.20%019%0.186CC..EExtended strand (participates in β ladder)trans-98.9135.2177.2-62.60000110.6S41 I42 E43 A44 Q94S41-S70 PolarHBondContact OG-OG 2.63Å; S41-S70 VanDerWaalsContact OG-OG 3.07Å; I42-S70 PolarHBondContact O-N 3.14Å; E43-S70 WeakPolarHBondContact CA-O 3.49Å; A44-S70 PolarHBondContact N-O 2.98Å; S70-Q94 WeakPolarHBondContact CA-O 3.34Å; S70-Q94 WeakPolarHBondContact OG-CB 3.44Å; S70-Q94 PolarHBondContact OG-OE1 2.88Å
71G98.1Very high97.8Very high0 Ų034.7 Ų34.70%020%0.199CC..EExtended strand (participates in β ladder)trans-108.7130.3166.600000110.7Q94 H96G71-Q94 PolarHBondContact N-O 2.87Å; G71-Q94 VanDerWaalsContact N-O 3.12Å; G71-H96 PolarHBondContact O-N 3.41Å
72L98Very high97.8Very high13 Ų1335.5 Ų35.57%0.06821%0.206CC..EExtended strand (participates in β ladder)trans-77.2134.9174-172.670.3000110.4R12 G45 F46 C83 H96 F98R12-L72 HydrophobicContact CG-CD2 4.5Å; G45-L72 PolarHBondContact O-N 2.96Å; G45-L72 VanDerWaalsContact O-N 3.17Å; F46-L72 HydrophobicContact CB-CB 4.43Å; F46-L72 HydrophobicContact CD1-CD2 4.39Å; F46-L72 WeakPolarHBondContact CD2-O 3.38Å; F46-L72 WeakPolarHBondContact CE2-O 3.41Å; L72-C83 PolarHBondContact O-SG 3.37Å; L72-C83 VanDerWaalsContact O-SG 3.34Å; L72-H96 CarbonylContact C-O 3.56Å; L72-H96 HydrophobicContact CD1-CB 4.17Å; L72-H96 WeakPolarHBondContact CD1-ND1 3.41Å; L72-F98 HydrophobicContact CD1-CD1 3.6Å; L72-F98 HydrophobicContact CD1-CE1 3.95Å; L72-F98 HydrophobicContact CD2-CD1 4.44Å; L72-F98 HydrophobicContact CD2-CE1 3.96Å; L72-F98 HydrophobicContact CG-CD1 4.01Å; L72-F98 HydrophobicContact CG-CE1 3.84Å
73A98.2Very high97.9Very high0 Ų032.5 Ų32.50%018%0.181CC..EExtended strand (participates in β ladder)trans-135134.5175.700000110.8D79 I80 H96 V97 F98A73-D79 HydrophobicContact CB-CB 3.91Å; A73-I80 HydrophobicContact CB-CG1 3.98Å; A73-H96 PolarHBondContact N-O 2.88Å; A73-V97 WeakPolarHBondContact O-CA 3.45Å; A73-F98 VanDerWaalsContact O-CD1 3.26Å; A73-F98 WeakPolarHBondContact O-CD1 3.41Å; A73-F98 PolarHBondContact O-N 3.31Å
74R97.9Very high98Very high120 Ų12034.5 Ų34.545%0.45318%0.184SC..EExtended strand (participates in β ladder)trans-63.8160.2162.9-67.9168-59.5-168.6-1.9109F46 V76 D79 F98F46-R74 HydrophobicContact CE1-CG 4.28Å; F46-R74 HydrophobicContact CZ-CG 3.79Å; R74-V76 HydrophobicContact CB-CG2 4.19Å; R74-V76 PolarHBondContact O-N 3.26Å; R74-D79 WeakPolarHBondContact CB-OD2 3.42Å; R74-D79 IonicContact CZ-OD2 2.89Å; R74-D79 PolarHBondContact N-OD2 3.1Å; R74-D79 IonicContact NE-OD2 3.22Å; R74-D79 PolarHBondContact NE-OD2 3.3Å; R74-D79 IonicContact NH2-OD1 2.69Å; R74-D79 PolarHBondContact NH2-OD1 3.3Å; R74-D79 VanDerWaalsContact NH2-OD1 3.08Å; R74-D79 IonicContact NH2-OD2 3.08Å; R74-D79 PolarHBondContact NH2-OD2 3.46Å; R74-F98 HydrophobicContact CB-CE1 4.45Å; R74-F98 HydrophobicContact CG-CE1 3.85Å; R74-F98 HydrophobicContact CG-CZ 3.71Å
75S97.4Very high98Very high13 Ų1338.1 Ų38.19%0.09120%0.201CC..SBendtrans-69.462.6173.5-63.10000112.8V97 F98 H124S75-V97 WeakPolarHBondContact OG-CG1 3.18Å; S75-F98 PolarHBondContact N-O 3.1Å; S75-F98 PolarHBondContact OG-O 3.07Å; S75-H124 PolarHBondContact O-CD2 3.05Å; S75-H124 PolarHBondContact O-CE1 2.77Å; S75-H124 PolarHBondContact O-NE2 3.33Å
76V97.5Very high98.1Very high59 Ų5934.6 Ų34.636%0.35818%0.179SC..SBendtrans-143.3140.7173.6-64.30000109.4R74 S78 D79 I80 H124R74-V76 HydrophobicContact CB-CG2 4.19Å; R74-V76 PolarHBondContact O-N 3.26Å; V76-S78 VanDerWaalsContact C-N 3.31Å; V76-S78 PolarHBondContact O-N 2.86Å; V76-D79 HydrophobicContact CG2-CB 3.76Å; V76-D79 VanDerWaalsContact CG2-OD1 3.32Å; V76-D79 WeakPolarHBondContact CG2-OD1 3.45Å; V76-D79 PolarHBondContact O-N 2.74Å; V76-I80 PolarHBondContact O-N 3.4Å; V76-H124 VanDerWaalsContact CA-CD2 3.4Å; V76-H124 WeakPolarHBondContact CA-CD2 3.44Å; V76-H124 WeakPolarHBondContact CA-NE2 3.44Å; V76-H124 PolarHBondContact N-CD2 3.14Å
77K98.2Very high98.2Very high87 Ų8730 Ų3038%0.37815%0.151SC..Hα-helixtrans-58.6-37.7-175-70.7177.9166.9137.90113.9D79 I80 D81 E123 Y127K77-D79 VanDerWaalsContact C-N 3.29Å; K77-D79 PolarHBondContact O-N 3.4Å; K77-I80 PolarHBondContact O-N 3.49Å; K77-D81 WeakPolarHBondContact O-CB 3.42Å; K77-D81 PolarHBondContact O-N 3.16Å; K77-E123 WeakPolarHBondContact CE-OE1 3.28Å; K77-E123 IonicContact NZ-OE1 3.48Å; K77-E123 PolarHBondContact NZ-OE1 3.44Å; K77-Y127 HydrophobicContact CB-CD1 4.15Å; K77-Y127 HydrophobicContact CB-CE1 3.79Å; K77-Y127 HydrophobicContact CD-CD2 4.42Å; K77-Y127 HydrophobicContact CD-CE1 4.47Å; K77-Y127 HydrophobicContact CD-CE2 4.38Å; K77-Y127 HydrophobicContact CD-CG 4.48Å; K77-Y127 HydrophobicContact CG-CD1 3.72Å; K77-Y127 HydrophobicContact CG-CD2 4.44Å; K77-Y127 HydrophobicContact CG-CE1 3.8Å; K77-Y127 HydrophobicContact CG-CG 4.05Å
78S98.2Very high98.2Very high75 Ų7535.1 Ų35.152%0.52417%0.173SC..Hα-helixtrans-60.6-36.2179.953.40000113.4V76 A82V76-S78 VanDerWaalsContact C-N 3.31Å; V76-S78 PolarHBondContact O-N 2.86Å; S78-A82 PolarHBondContact O-N 2.82Å
79D98.4Very high98.1Very high5 Ų540 Ų403%0.02720%0.198CC..Hα-helixtrans-76.3-38.2-178.7-71.625.8000110.9F46 A48 A73 R74 V76 K77 D81 A82 C83F46-D79 HydrophobicContact CE2-CB 4.35Å; F46-D79 WeakPolarHBondContact CE2-OD2 3.41Å; F46-D79 VanDerWaalsContact CZ-OD2 3.24Å; F46-D79 WeakPolarHBondContact CZ-OD2 3.24Å; A48-D79 HydrophobicContact CB-CB 3.98Å; A73-D79 HydrophobicContact CB-CB 3.91Å; R74-D79 WeakPolarHBondContact CB-OD2 3.42Å; R74-D79 IonicContact CZ-OD2 2.89Å; R74-D79 PolarHBondContact N-OD2 3.1Å; R74-D79 IonicContact NE-OD2 3.22Å; R74-D79 PolarHBondContact NE-OD2 3.3Å; R74-D79 IonicContact NH2-OD1 2.69Å; R74-D79 PolarHBondContact NH2-OD1 3.3Å; R74-D79 VanDerWaalsContact NH2-OD1 3.08Å; R74-D79 IonicContact NH2-OD2 3.08Å; R74-D79 PolarHBondContact NH2-OD2 3.46Å; V76-D79 HydrophobicContact CG2-CB 3.76Å; V76-D79 VanDerWaalsContact CG2-OD1 3.32Å; V76-D79 WeakPolarHBondContact CG2-OD1 3.45Å; V76-D79 PolarHBondContact O-N 2.74Å; K77-D79 VanDerWaalsContact C-N 3.29Å; K77-D79 PolarHBondContact O-N 3.4Å; D79-D81 VanDerWaalsContact C-N 3.32Å; D79-A82 PolarHBondContact O-N 3.32Å; D79-C83 PolarHBondContact O-N 2.82Å; D79-C83 PolarHBondContact O-SG 3.09Å
80I98.6Very high98Very high0 Ų040.5 Ų40.50%020%0.202CC..Hα-helixtrans-63.8-40.5172.5-62.9166.1000110.1A73 V76 K77 C83 Y84 V97 H124 Y127 A128 K131 F132A73-I80 HydrophobicContact CB-CG1 3.98Å; V76-I80 PolarHBondContact O-N 3.4Å; K77-I80 PolarHBondContact O-N 3.49Å; I80-C83 PolarHBondContact O-N 2.82Å; I80-Y84 WeakPolarHBondContact O-CB 3.47Å; I80-Y84 PolarHBondContact O-N 3.29Å; I80-V97 HydrophobicContact CD1-CG2 4.31Å; I80-V97 HydrophobicContact CG1-CG2 4.29Å; I80-H124 HydrophobicContact CD1-CB 4.09Å; I80-H124 WeakPolarHBondContact CD1-O 3.38Å; I80-Y127 HydrophobicContact CB-CD1 4.08Å; I80-Y127 HydrophobicContact CB-CE1 4.2Å; I80-Y127 HydrophobicContact CD1-CD1 3.9Å; I80-Y127 HydrophobicContact CG2-CD1 3.82Å; I80-Y127 HydrophobicContact CG2-CE1 4.01Å; I80-A128 HydrophobicContact CD1-CB 4.24Å; I80-A128 HydrophobicContact CG2-CB 4.11Å; I80-K131 HydrophobicContact CG2-CD 4.5Å; I80-F132 HydrophobicContact CG2-CE2 4.45Å
81D98.5Very high97.9Very high51 Ų5146.7 Ų46.727%0.27323%0.229SC..Hα-helixtrans-62.4-43.8174.5-68.3-23000111.3K77 D79 C83 Y84 E85 Y127 K131K77-D81 WeakPolarHBondContact O-CB 3.42Å; K77-D81 PolarHBondContact O-N 3.16Å; D79-D81 VanDerWaalsContact C-N 3.32Å; D81-C83 VanDerWaalsContact C-N 3.34Å; D81-C83 PolarHBondContact O-N 2.88Å; D81-Y84 PolarHBondContact O-N 3.49Å; D81-E85 WeakPolarHBondContact O-CG 3.46Å; D81-E85 PolarHBondContact O-N 3.38Å; D81-Y127 WeakPolarHBondContact OD1-CE1 3.1Å; D81-Y127 PolarHBondContact OD1-OH 3.27Å; D81-Y127 PolarHBondContact OD2-OH 3.02Å; D81-K131 WeakPolarHBondContact OD1-CE 3.43Å; D81-K131 IonicContact OD1-NZ 3.78Å; D81-K131 PolarHBondContact OD1-NZ 2.86Å
82A98.4Very high97.9Very high18 Ų1852.3 Ų52.315%0.14925%0.251CS..Hα-helixtrans-61.7-40.8175.600000112.2P47 A48 F54 S78 D79 E85 A86P47-A82 HydrophobicContact CB-CB 4.18Å; A48-A82 HydrophobicContact CB-CB 3.97Å; F54-A82 WeakPolarHBondContact CE2-O 3.44Å; S78-A82 PolarHBondContact O-N 2.82Å; D79-A82 PolarHBondContact O-N 3.32Å; A82-E85 PolarHBondContact O-N 3.11Å; A82-A86 WeakPolarHBondContact O-CB 3.37Å; A82-A86 PolarHBondContact O-N 3.22Å
83C98.3Very high97.9Very high0 Ų053.6 Ų53.60%026%0.261CS..Hα-helixtrans-61.9-46173.1-66.70000111.6P47 L72 D79 I80 D81 E85 A86 L87 F132P47-C83 HydrophobicContact CG-CB 4.47Å; L72-C83 PolarHBondContact O-SG 3.37Å; L72-C83 VanDerWaalsContact O-SG 3.34Å; D79-C83 PolarHBondContact O-N 2.82Å; D79-C83 PolarHBondContact O-SG 3.09Å; I80-C83 PolarHBondContact O-N 2.82Å; D81-C83 VanDerWaalsContact C-N 3.34Å; D81-C83 PolarHBondContact O-N 2.88Å; C83-E85 VanDerWaalsContact C-N 3.31Å; C83-E85 PolarHBondContact O-N 3.25Å; C83-A86 PolarHBondContact O-N 3.41Å; C83-L87 HydrophobicContact CB-CD1 4.33Å; C83-L87 VanDerWaalsContact O-CB 3.27Å; C83-L87 WeakPolarHBondContact O-CB 3.4Å; C83-L87 WeakPolarHBondContact O-CD1 3.06Å; C83-L87 WeakPolarHBondContact O-CG 3.08Å; C83-L87 PolarHBondContact O-N 2.86Å; C83-F132 HydrophobicContact CB-CZ 4.18Å
84Y98.4Very high97.9Very high89 Ų8954.2 Ų54.235%0.34926%0.264SS..Hα-helixtrans-59.9-42.9179.5-179.3-103.1000112I80 D81 K88 K131 F132I80-Y84 WeakPolarHBondContact O-CB 3.47Å; I80-Y84 PolarHBondContact O-N 3.29Å; D81-Y84 PolarHBondContact O-N 3.49Å; Y84-K88 VanDerWaalsContact O-CG 3.3Å; Y84-K88 WeakPolarHBondContact O-CG 3.27Å; Y84-K88 PolarHBondContact O-N 3.11Å; Y84-K131 HydrophobicContact CD1-CD 4.27Å; Y84-K131 HydrophobicContact CD2-CB 3.7Å; Y84-K131 HydrophobicContact CD2-CD 4.07Å; Y84-K131 HydrophobicContact CD2-CG 4.33Å; Y84-K131 HydrophobicContact CE2-CB 4.13Å; Y84-K131 WeakPolarHBondContact CE2-O 3.28Å; Y84-K131 HydrophobicContact CG-CB 4.3Å; Y84-K131 HydrophobicContact CG-CD 3.82Å; Y84-F132 VanDerWaalsContact CA-CZ 3.43Å; Y84-F132 HydrophobicContact CD2-CE2 4.22Å; Y84-F132 HydrophobicContact CD2-CZ 4.17Å
85E98.4Very high97.9Very high86 Ų8648.5 Ų48.540%0.40224%0.243SC..Hα-helixtrans-69.2-40178.2-67.5-61.4130.300112.9F54 D81 A82 C83 L87 K88F54-E85 HydrophobicContact CE2-CB 3.9Å; F54-E85 HydrophobicContact CZ-CB 3.89Å; D81-E85 WeakPolarHBondContact O-CG 3.46Å; D81-E85 PolarHBondContact O-N 3.38Å; A82-E85 PolarHBondContact O-N 3.11Å; C83-E85 VanDerWaalsContact C-N 3.31Å; C83-E85 PolarHBondContact O-N 3.25Å; E85-L87 VanDerWaalsContact C-N 3.35Å; E85-K88 VanDerWaalsContact CD-CE 3.48Å; E85-K88 WeakPolarHBondContact OE1-CE 3.28Å; E85-K88 IonicContact OE1-NZ 3.39Å; E85-K88 PolarHBondContact OE1-NZ 2.93Å; E85-K88 WeakPolarHBondContact OE2-CE 3.34Å; E85-K88 IonicContact OE2-NZ 3.58Å; E85-K88 PolarHBondContact OE2-NZ 3.37Å
86A98.1Very high98Very high0 Ų048 Ų480%024%0.239CC..Hα-helixtrans-71-29.3179.400000113.1P47 F54 V57 R58 S61 A82 C83P47-A86 HydrophobicContact CB-CB 3.98Å; P47-A86 HydrophobicContact CG-CB 4.05Å; F54-A86 HydrophobicContact CD2-CB 3.88Å; F54-A86 HydrophobicContact CE2-CB 3.73Å; F54-A86 HydrophobicContact CG-CB 4.38Å; F54-A86 HydrophobicContact CZ-CB 4.09Å; V57-A86 HydrophobicContact CB-CB 4.14Å; V57-A86 HydrophobicContact CG1-CB 3.79Å; R58-A86 WeakPolarHBondContact CA-O 3.31Å; S61-A86 PolarHBondContact OG-O 2.85Å; A82-A86 WeakPolarHBondContact O-CB 3.37Å; A82-A86 PolarHBondContact O-N 3.22Å; C83-A86 PolarHBondContact O-N 3.41Å
87L98.4Very high98.1Very high2 Ų245.2 Ų45.21%0.0122%0.222CC..THydrogen-bonded Turntrans-97.17.2-173.8-63.4169.1000113.9V57 S61 V69 C83 E85 D89 A90 Q94 F132V57-L87 HydrophobicContact CG1-CD2 3.55Å; V57-L87 HydrophobicContact CG1-CG 4.12Å; S61-L87 WeakPolarHBondContact OG-CD2 3.34Å; V69-L87 HydrophobicContact CB-CD2 3.93Å; V69-L87 HydrophobicContact CG1-CD2 3.53Å; C83-L87 HydrophobicContact CB-CD1 4.33Å; C83-L87 VanDerWaalsContact O-CB 3.27Å; C83-L87 WeakPolarHBondContact O-CB 3.4Å; C83-L87 WeakPolarHBondContact O-CD1 3.06Å; C83-L87 WeakPolarHBondContact O-CG 3.08Å; C83-L87 PolarHBondContact O-N 2.86Å; E85-L87 VanDerWaalsContact C-N 3.35Å; L87-D89 PolarHBondContact O-N 3.03Å; L87-A90 HydrophobicContact CB-CB 4.49Å; L87-A90 WeakPolarHBondContact O-CB 3.32Å; L87-A90 PolarHBondContact O-N 2.8Å; L87-Q94 WeakPolarHBondContact CD1-O 3.44Å; L87-F132 HydrophobicContact CB-CE1 4.34Å; L87-F132 HydrophobicContact CD1-CE1 3.72Å; L87-F132 HydrophobicContact CD1-CZ 4.04Å
88K96.8Very high98.1Very high113 Ų11343 Ų4349%0.49121%0.213SC..THydrogen-bonded Turntrans-55.9-35.3-176.3-76.6-174.8171.3167.10114.3Y84 E85Y84-K88 VanDerWaalsContact O-CG 3.3Å; Y84-K88 WeakPolarHBondContact O-CG 3.27Å; Y84-K88 PolarHBondContact O-N 3.11Å; E85-K88 VanDerWaalsContact CD-CE 3.48Å; E85-K88 WeakPolarHBondContact OE1-CE 3.28Å; E85-K88 IonicContact OE1-NZ 3.39Å; E85-K88 PolarHBondContact OE1-NZ 2.93Å; E85-K88 WeakPolarHBondContact OE2-CE 3.34Å; E85-K88 IonicContact OE2-NZ 3.58Å; E85-K88 PolarHBondContact OE2-NZ 3.37Å
89D96.8Very high98.1Very high107 Ų10740.2 Ų40.257%0.57219%0.192SC*.THydrogen-bonded Turntrans-89.9-4-178.4-62.1-38.8000112.7A62 L87 K91A62-D89 HydrophobicContact CB-CB 4.23Å; L87-D89 PolarHBondContact O-N 3.03Å; D89-K91 PolarHBondContact O-N 2.75Å
90A97.7Very high98.1Very high12 Ų1240 Ų4010%0.09919%0.191CC..  trans-72.6126.7177.500000110.1S61 V69 L87 Y92S61-A90 WeakPolarHBondContact O-CA 3.48Å; V69-A90 HydrophobicContact CB-CB 4.14Å; V69-A90 HydrophobicContact CG2-CB 4.3Å; L87-A90 HydrophobicContact CB-CB 4.49Å; L87-A90 WeakPolarHBondContact O-CB 3.32Å; L87-A90 PolarHBondContact O-N 2.8Å; A90-Y92 PolarHBondContact O-N 2.61Å
91K96.7Very high98.1Very high131 Ų13140 Ų4057%0.5719%0.191SC*.SBendtrans-61.4-34.1176-173.6178.7171.2-166.70112.8T65 D89T65-K91 VanDerWaalsContact O-CD 3.29Å; T65-K91 WeakPolarHBondContact O-CD 2.96Å; T65-K91 PolarHBondContact O-NZ 2.92Å; D89-K91 PolarHBondContact O-N 2.75Å
92Y97.6Very high98Very high117 Ų11737.6 Ų37.646%0.45918%0.178SC..SBendtrans-132.991.3175.6-53.4-72.4000108.6A68 V69 A90A68-Y92 CarbonylContact C-O 3.48Å; A68-Y92 VanDerWaalsContact CA-O 3.28Å; A68-Y92 WeakPolarHBondContact CA-O 3.42Å; A68-Y92 WeakPolarHBondContact CB-O 3.39Å; V69-Y92 PolarHBondContact N-O 3.5Å; A90-Y92 PolarHBondContact O-N 2.61Å
93S98.1Very high98Very high41 Ų4139.1 Ų39.129%0.28719%0.186SC..EExtended strand (participates in β ladder)trans-89.7141.6-179.457.30000112
94Q98.2Very high97.9Very high12 Ų1243.1 Ų43.16%0.05621%0.206CC..EExtended strand (participates in β ladder)trans-133.8147.6175.4-48.1-174.7-0.200109.9S41 A68 V69 S70 G71 L87 V134 R223S41-Q94 PolarHBondContact OG-OE1 3.36Å; A68-Q94 HydrophobicContact CB-CG 4.15Å; V69-Q94 PolarHBondContact O-N 3.49Å; S70-Q94 WeakPolarHBondContact CA-O 3.34Å; S70-Q94 WeakPolarHBondContact OG-CB 3.44Å; S70-Q94 PolarHBondContact OG-OE1 2.88Å; G71-Q94 PolarHBondContact N-O 2.87Å; G71-Q94 VanDerWaalsContact N-O 3.12Å; L87-Q94 WeakPolarHBondContact CD1-O 3.44Å; Q94-V134 WeakPolarHBondContact CA-O 3.41Å; Q94-V134 HydrophobicContact CB-CB 4.33Å; Q94-V134 HydrophobicContact CB-CG1 4.05Å; Q94-V134 HydrophobicContact CG-CB 3.91Å; Q94-V134 HydrophobicContact CG-CG1 3.64Å; Q94-R223 VanDerWaalsContact OE1-NH1 3.17Å
95C98.5Very high97.8Very high0 Ų040.6 Ų40.60%020%0.198CC..EExtended strand (participates in β ladder)trans-114.8125172.4-172.80000109.6F132 V134 V135 E136C95-F132 HydrophobicContact CB-CB 4.4Å; C95-F132 HydrophobicContact CB-CD1 4.19Å; C95-F132 HydrophobicContact CB-CD2 3.43Å; C95-F132 VanDerWaalsContact CB-CD2 3.43Å; C95-F132 HydrophobicContact CB-CE1 4.26Å; C95-F132 HydrophobicContact CB-CE2 3.53Å; C95-F132 HydrophobicContact CB-CG 3.76Å; C95-F132 HydrophobicContact CB-CZ 3.92Å; C95-V134 PolarHBondContact N-O 2.92Å; C95-V135 WeakPolarHBondContact O-CA 3.38Å; C95-E136 PolarHBondContact O-N 3.32Å
96H98.7Very high97.7Very high4 Ų437.8 Ų37.82%0.01918%0.184CC..EExtended strand (participates in β ladder)trans-102109.6175.2179.7-175.3000109.1E43 G71 L72 A73 E136 S138E43-H96 IonicContact OE2-CE1 3.97Å; E43-H96 IonicContact OE2-CG 2.74Å; E43-H96 IonicContact OE2-ND1 3.74Å; E43-H96 PolarHBondContact OE2-ND1 2.87Å; G71-H96 PolarHBondContact O-N 3.41Å; L72-H96 CarbonylContact C-O 3.56Å; L72-H96 HydrophobicContact CD1-CB 4.17Å; L72-H96 WeakPolarHBondContact CD1-ND1 3.41Å; A73-H96 PolarHBondContact N-O 2.88Å; H96-E136 WeakPolarHBondContact CA-O 3.41Å; H96-E136 HydrophobicContact CB-CB 4.29Å; H96-E136 IonicContact CE1-OE1 2.83Å; H96-E136 IonicContact CG-OE1 3.55Å; H96-E136 IonicContact ND1-OE1 2.8Å; H96-S138 PolarHBondContact CE1-OG 3.28Å; H96-S138 WeakPolarHBondContact NE2-CB 3.48Å; H96-S138 PolarHBondContact NE2-OG 3.01Å
97V98.6Very high97.6Very high0 Ų043.4 Ų43.40%021%0.21CC..EExtended strand (participates in β ladder)trans-103.1137.9178.7-175.60000109.9A73 S75 I80 H124 A128 E136 F137 S138A73-V97 WeakPolarHBondContact O-CA 3.45Å; S75-V97 WeakPolarHBondContact OG-CG1 3.18Å; I80-V97 HydrophobicContact CD1-CG2 4.31Å; I80-V97 HydrophobicContact CG1-CG2 4.29Å; V97-H124 HydrophobicContact CG1-CB 4.42Å; V97-A128 HydrophobicContact CG2-CB 3.82Å; V97-E136 PolarHBondContact N-O 3.19Å; V97-F137 VanDerWaalsContact O-CA 3.27Å; V97-F137 WeakPolarHBondContact O-CA 3.46Å; V97-F137 WeakPolarHBondContact O-CD2 3.32Å; V97-S138 PolarHBondContact O-N 2.84Å
98F98.5Very high97.5Very high41 Ų4150.9 Ų50.918%0.1824%0.239CC..EExtended strand (participates in β ladder)trans-138158.7178.575.6-78.4000113.7L72 A73 R74 S75 S138 E140L72-F98 HydrophobicContact CD1-CD1 3.6Å; L72-F98 HydrophobicContact CD1-CE1 3.95Å; L72-F98 HydrophobicContact CD2-CD1 4.44Å; L72-F98 HydrophobicContact CD2-CE1 3.96Å; L72-F98 HydrophobicContact CG-CD1 4.01Å; L72-F98 HydrophobicContact CG-CE1 3.84Å; A73-F98 VanDerWaalsContact O-CD1 3.26Å; A73-F98 WeakPolarHBondContact O-CD1 3.41Å; A73-F98 PolarHBondContact O-N 3.31Å; R74-F98 HydrophobicContact CB-CE1 4.45Å; R74-F98 HydrophobicContact CG-CE1 3.85Å; R74-F98 HydrophobicContact CG-CZ 3.71Å; S75-F98 PolarHBondContact N-O 3.1Å; S75-F98 PolarHBondContact OG-O 3.07Å; F98-S138 VanDerWaalsContact CA-O 3.3Å; F98-S138 WeakPolarHBondContact CA-O 3.42Å; F98-S138 WeakPolarHBondContact CB-O 3.06Å; F98-E140 HydrophobicContact CD2-CB 4.17Å
99I98.5Very high97.4Very high16 Ų1650.5 Ų50.58%0.08224%0.237CC..EExtended strand (participates in β ladder)trans-155.3143.6167.2-172.5162.2000110.5L110 I117 I120 I121 F137 S138 P139 E140I99-L110 HydrophobicContact CD1-CD1 4.2Å; I99-L110 HydrophobicContact CG1-CD1 3.83Å; I99-I117 HydrophobicContact CD1-CG1 4.48Å; I99-I117 HydrophobicContact CD1-CG2 4.42Å; I99-I117 HydrophobicContact CG2-CG2 4.26Å; I99-I120 HydrophobicContact CD1-CB 4.21Å; I99-I120 HydrophobicContact CD1-CD1 4.14Å; I99-I120 HydrophobicContact CD1-CG2 3.64Å; I99-I121 HydrophobicContact CG2-CD1 4.08Å; I99-I121 HydrophobicContact CG2-CG1 3.72Å; I99-F137 HydrophobicContact CG2-CE2 3.99Å; I99-F137 HydrophobicContact CG2-CZ 3.92Å; I99-S138 PolarHBondContact N-O 3.46Å; I99-S138 VanDerWaalsContact N-O 3.17Å; I99-P139 CarbonylContact O-C 3.6Å; I99-P139 WeakPolarHBondContact O-CA 3.18Å; I99-E140 PolarHBondContact O-N 3.42Å
100A97.9Very high97.4Very high1 Ų147.8 Ų47.81%0.00822%0.222CC..EExtended strand (participates in β ladder)trans-68.5134.2176.600000112.4H105 L110 E140A100-H105 HydrophobicContact CB-CB 3.47Å; A100-H105 VanDerWaalsContact CB-CB 3.47Å; A100-L110 HydrophobicContact CB-CD1 4.01Å; A100-L110 HydrophobicContact CB-CG 4.46Å; A100-L110 WeakPolarHBondContact O-CD1 3.3Å; A100-E140 WeakPolarHBondContact CA-O 3.37Å; A100-E140 HydrophobicContact CB-CB 4.25Å; A100-E140 HydrophobicContact CB-CG 4.3Å; A100-E140 WeakPolarHBondContact CB-OE2 3.28Å
101T98.3Very high97.3Very high0 Ų055.3 Ų55.30%025%0.253CS..  trans-119-17.1-176.453.40000114.8R106 I117 P139 E140 T145 V153T101-R106 WeakPolarHBondContact O-CD 3.28Å; T101-R106 PolarHBondContact O-NH1 2.99Å; T101-I117 HydrophobicContact CG2-CG2 4.31Å; T101-P139 HydrophobicContact CG2-CB 3.68Å; T101-P139 WeakPolarHBondContact OG1-CB 3.14Å; T101-E140 PolarHBondContact N-O 2.86Å; T101-T145 PolarHBondContact OG1-OG1 3.39Å; T101-V153 HydrophobicContact CG2-CB 4.49Å; T101-V153 HydrophobicContact CG2-CG1 3.86Å; T101-V153 HydrophobicContact CG2-CG2 3.97Å
102S97.7Very high97.3Very high0 Ų052.7 Ų52.70%024%0.241CC..SBendtrans-66.4151.4-175.173.80000113I104 H105 R106 D141 T145S102-I104 PolarHBondContact O-N 2.89Å; S102-I104 VanDerWaalsContact O-N 3.16Å; S102-I104 WeakPolarHBondContact OG-CG2 2.97Å; S102-H105 PolarHBondContact O-N 3.04Å; S102-H105 PolarHBondContact OG-CD2 3.14Å; S102-H105 PolarHBondContact OG-N 2.94Å; S102-R106 WeakPolarHBondContact O-CG 3.47Å; S102-R106 PolarHBondContact O-N 3.11Å; S102-D141 WeakPolarHBondContact CB-OD2 3.4Å; S102-D141 PolarHBondContact OG-OD2 3.45Å; S102-T145 WeakPolarHBondContact CA-OG1 3.41Å; S102-T145 PolarHBondContact N-OG1 3.35Å
103P97.3Very high97.3Very high49 Ų4950.3 Ų50.332%0.31824%0.239SC..Hα-helixtrans-49.7-44.1179.7-26.833.4000113.7H105 R106 E107 R144 E146P103-H105 PolarHBondContact O-N 3.28Å; P103-R106 PolarHBondContact O-N 3.23Å; P103-E107 WeakPolarHBondContact O-CB 3.3Å; P103-E107 PolarHBondContact O-N 2.85Å; P103-R144 WeakPolarHBondContact CD-O 3.39Å; P103-E146 HydrophobicContact CG-CG 4.37Å; P103-E146 WeakPolarHBondContact CG-OE2 3.15Å
104I96.7Very high97.3Very high84 Ų8451.2 Ų51.243%0.43124%0.238SC..Hα-helixtrans-65.2-39.6-179.6-168.5172000111.8S102 Y108S102-I104 PolarHBondContact O-N 2.89Å; S102-I104 VanDerWaalsContact O-N 3.16Å; S102-I104 WeakPolarHBondContact OG-CG2 2.97Å; I104-Y108 HydrophobicContact CG1-CD2 3.86Å; I104-Y108 HydrophobicContact CG1-CE2 4.46Å; I104-Y108 WeakPolarHBondContact O-CB 3.37Å; I104-Y108 WeakPolarHBondContact O-CD2 3.31Å; I104-Y108 PolarHBondContact O-N 2.61Å
105H96.5Very high97.3Very high36 Ų3656.3 Ų56.317%0.16726%0.262CS..Iπ-helixtrans-72.3-37.7175.2-77.1-57.8000112.5A100 S102 P103 E107 K109 L110 D141A100-H105 HydrophobicContact CB-CB 3.47Å; A100-H105 VanDerWaalsContact CB-CB 3.47Å; S102-H105 PolarHBondContact O-N 3.04Å; S102-H105 PolarHBondContact OG-CD2 3.14Å; S102-H105 PolarHBondContact OG-N 2.94Å; P103-H105 PolarHBondContact O-N 3.28Å; H105-E107 VanDerWaalsContact C-N 3.34Å; H105-E107 PolarHBondContact O-N 2.7Å; H105-K109 HydrophobicContact CB-CB 4.27Å; H105-K109 HydrophobicContact CB-CD 4.47Å; H105-K109 WeakPolarHBondContact ND1-CD 3.41Å; H105-K109 CarbonylContact O-C 3.58Å; H105-K109 WeakPolarHBondContact O-CA 3.22Å; H105-K109 WeakPolarHBondContact O-CB 3.21Å; H105-K109 PolarHBondContact O-N 3.01Å; H105-L110 PolarHBondContact O-N 2.72Å; H105-D141 VanDerWaalsContact CD2-CB 3.49Å; H105-D141 WeakPolarHBondContact CD2-CB 3.3Å; H105-D141 IonicContact CD2-OD2 2.67Å; H105-D141 PolarHBondContact CD2-OD2 2.81Å; H105-D141 VanDerWaalsContact CD2-OD2 3.23Å; H105-D141 IonicContact NE2-OD2 2.8Å
106R97Very high97.3Very high28 Ų2860.1 Ų60.111%0.10628%0.28CS..Iπ-helixtrans-60.1-44.9175-62.7-166-54-101.13.9111.6T101 S102 P103 K111 K112 K114 I117 E146T101-R106 WeakPolarHBondContact O-CD 3.28Å; T101-R106 PolarHBondContact O-NH1 2.99Å; S102-R106 WeakPolarHBondContact O-CG 3.47Å; S102-R106 PolarHBondContact O-N 3.11Å; P103-R106 PolarHBondContact O-N 3.23Å; R106-K111 WeakPolarHBondContact O-CA 3.13Å; R106-K111 PolarHBondContact O-N 2.83Å; R106-K112 PolarHBondContact O-N 2.78Å; R106-K114 VanDerWaalsContact NH2-CE 3.26Å; R106-I117 HydrophobicContact CB-CD1 4.4Å; R106-I117 HydrophobicContact CG-CD1 3.46Å; R106-I117 VanDerWaalsContact CG-CD1 3.46Å; R106-E146 IonicContact CZ-OE1 3.64Å; R106-E146 IonicContact CZ-OE2 2.87Å; R106-E146 IonicContact NH1-OE1 2.86Å; R106-E146 IonicContact NH1-OE2 2.75Å; R106-E146 PolarHBondContact NH1-OE2 3.39Å; R106-E146 IonicContact NH2-OE1 3.91Å; R106-E146 PolarHBondContact NH2-OE1 3.47Å; R106-E146 IonicContact NH2-OE2 2.6Å; R106-E146 PolarHBondContact NH2-OE2 2.94Å
107E96.1Very high97.3Very high117 Ų11760 Ų6055%0.54728%0.279SS..Iπ-helixtrans-74.5-50.1-177.4-173.4177.516900112.7P103 H105P103-E107 WeakPolarHBondContact O-CB 3.3Å; P103-E107 PolarHBondContact O-N 2.85Å; H105-E107 VanDerWaalsContact C-N 3.34Å; H105-E107 PolarHBondContact O-N 2.7Å
108Y96.2Very high97.3Very high159 Ų15961.3 Ų61.362%0.62429%0.286SS*.Iπ-helixtrans-103.2-28.9-167.4-62.1-79.6000114.7I104I104-Y108 HydrophobicContact CG1-CD2 3.86Å; I104-Y108 HydrophobicContact CG1-CE2 4.46Å; I104-Y108 WeakPolarHBondContact O-CB 3.37Å; I104-Y108 WeakPolarHBondContact O-CD2 3.31Å; I104-Y108 PolarHBondContact O-N 2.61Å
109K94.7Very high97.3Very high105 Ų10564.5 Ų64.546%0.45731%0.305SS..Iπ-helixtrans-94.8-57-177.9-178-178.8178.4-175.10111.9H105 E140H105-K109 HydrophobicContact CB-CB 4.27Å; H105-K109 HydrophobicContact CB-CD 4.47Å; H105-K109 WeakPolarHBondContact ND1-CD 3.41Å; H105-K109 CarbonylContact O-C 3.58Å; H105-K109 WeakPolarHBondContact O-CA 3.22Å; H105-K109 WeakPolarHBondContact O-CB 3.21Å; H105-K109 PolarHBondContact O-N 3.01Å; K109-E140 IonicContact NZ-OE1 3.76Å; K109-E140 PolarHBondContact NZ-OE1 3.36Å; K109-E140 IonicContact NZ-OE2 2.8Å; K109-E140 PolarHBondContact NZ-OE2 3.05Å
110L95.8Very high97.3Very high50 Ų5065 Ų6526%0.26231%0.308SS..Iπ-helixtrans-90.8-32.2-171.9-60.6-177000113.2I99 A100 H105 K112 I117I99-L110 HydrophobicContact CD1-CD1 4.2Å; I99-L110 HydrophobicContact CG1-CD1 3.83Å; A100-L110 HydrophobicContact CB-CD1 4.01Å; A100-L110 HydrophobicContact CB-CG 4.46Å; A100-L110 WeakPolarHBondContact O-CD1 3.3Å; H105-L110 PolarHBondContact O-N 2.72Å; L110-K112 HydrophobicContact CB-CB 4.32Å; L110-K112 HydrophobicContact CB-CD 4.48Å; L110-K112 HydrophobicContact CB-CG 4.28Å; L110-I117 HydrophobicContact CD1-CD1 4.24Å
111K96.7Very high97.4Very high170 Ų17065 Ų6574%0.73931%0.307SS*.  trans54.650.8-172.3-57.8179.4179.7179.50111.7R106R106-K111 WeakPolarHBondContact O-CA 3.13Å; R106-K111 PolarHBondContact O-N 2.83Å
112K96.8Very high97.4Very high76 Ų7671.2 Ų71.233%0.3333%0.334SS..  trans-130.3147.5-176.2-71.2-173.8177.3-62.50112.3R106 L110 E116 I117 I120R106-K112 PolarHBondContact O-N 2.78Å; L110-K112 HydrophobicContact CB-CB 4.32Å; L110-K112 HydrophobicContact CB-CD 4.48Å; L110-K112 HydrophobicContact CB-CG 4.28Å; K112-E116 VanDerWaalsContact CA-OE2 3.25Å; K112-E116 WeakPolarHBondContact CA-OE2 3.38Å; K112-E116 HydrophobicContact CB-CB 4.18Å; K112-I117 HydrophobicContact CB-CD1 4.31Å; K112-I117 HydrophobicContact CB-CG1 4.02Å; K112-I120 HydrophobicContact CD-CD1 3.47Å; K112-I120 VanDerWaalsContact CD-CD1 3.47Å
113T97.5Very high97.4Very high68 Ų6875.6 Ų75.642%0.41736%0.355SS..  trans-73.9170.4172.682.20000111.6E115 E116 I117T113-E115 VanDerWaalsContact C-N 3.29Å; T113-E115 WeakPolarHBondContact CB-OE2 3.2Å; T113-E115 PolarHBondContact O-N 2.77Å; T113-E115 PolarHBondContact OG1-N 2.82Å; T113-E115 PolarHBondContact OG1-OE2 3.04Å; T113-E116 PolarHBondContact N-OE2 2.76Å; T113-E116 PolarHBondContact OG1-N 2.99Å; T113-I117 WeakPolarHBondContact O-CG1 3.23Å; T113-I117 PolarHBondContact O-N 2.84Å
114K98.2Very high97.5Very high59 Ų5974 Ų7426%0.25734%0.343SS..Hα-helixtrans-59.8-43.1175.5-77.1-172.5171.9-176.70111R106 I117 L118 E146 Y149R106-K114 VanDerWaalsContact NH2-CE 3.26Å; K114-I117 PolarHBondContact O-N 3.39Å; K114-L118 WeakPolarHBondContact O-CG 3.35Å; K114-L118 PolarHBondContact O-N 3.42Å; K114-L118 VanDerWaalsContact O-N 3.16Å; K114-E146 WeakPolarHBondContact CE-OE1 3.16Å; K114-E146 IonicContact NZ-OE1 2.7Å; K114-E146 PolarHBondContact NZ-OE1 3.23Å; K114-E146 IonicContact NZ-OE2 2.62Å; K114-Y149 VanDerWaalsContact CA-OH 3.28Å; K114-Y149 WeakPolarHBondContact CA-OH 3.47Å; K114-Y149 HydrophobicContact CB-CD2 4.11Å; K114-Y149 HydrophobicContact CB-CE2 3.44Å; K114-Y149 VanDerWaalsContact CB-CE2 3.44Å; K114-Y149 HydrophobicContact CD-CD1 4.19Å; K114-Y149 HydrophobicContact CD-CD2 3.59Å; K114-Y149 HydrophobicContact CD-CE1 4.38Å; K114-Y149 HydrophobicContact CD-CE2 3.82Å; K114-Y149 HydrophobicContact CD-CG 3.8Å; K114-Y149 HydrophobicContact CG-CD1 4.25Å; K114-Y149 HydrophobicContact CG-CD2 3.92Å; K114-Y149 HydrophobicContact CG-CE1 3.95Å; K114-Y149 HydrophobicContact CG-CE2 3.59Å; K114-Y149 HydrophobicContact CG-CG 4.24Å; K114-Y149 PolarHBondContact O-OH 2.87Å
115E98.2Very high97.6Very high120 Ų12070 Ų7056%0.56132%0.323SS*.Hα-helixtrans-67.1-44.6-178.5-59.970-153.800111.7T113 I117 L118 D119T113-E115 VanDerWaalsContact C-N 3.29Å; T113-E115 WeakPolarHBondContact CB-OE2 3.2Å; T113-E115 PolarHBondContact O-N 2.77Å; T113-E115 PolarHBondContact OG1-N 2.82Å; T113-E115 PolarHBondContact OG1-OE2 3.04Å; E115-I117 PolarHBondContact O-N 3Å; E115-L118 PolarHBondContact O-N 2.88Å; E115-L118 VanDerWaalsContact O-N 3.12Å; E115-D119 PolarHBondContact O-N 2.95Å
116E98.2Very high97.7Very high80 Ų8071.6 Ų71.637%0.37434%0.335SS..Hα-helixtrans-59.5-36.7177-71.1-178.8106.100112.2K112 T113 I120K112-E116 VanDerWaalsContact CA-OE2 3.25Å; K112-E116 WeakPolarHBondContact CA-OE2 3.38Å; K112-E116 HydrophobicContact CB-CB 4.18Å; T113-E116 PolarHBondContact N-OE2 2.76Å; T113-E116 PolarHBondContact OG1-N 2.99Å; E116-I120 WeakPolarHBondContact O-CD1 3.34Å; E116-I120 VanDerWaalsContact O-CG1 3.23Å; E116-I120 WeakPolarHBondContact O-CG1 3.23Å; E116-I120 PolarHBondContact O-N 3.29Å
117I98.4Very high97.8Very high0 Ų072.9 Ų72.90%034%0.34CS..Hα-helixtrans-69-42.6176.5-70.4167.7000110.8I99 T101 R106 L110 K112 T113 K114 E115 D119 I120 I121 Y149I99-I117 HydrophobicContact CD1-CG1 4.48Å; I99-I117 HydrophobicContact CD1-CG2 4.42Å; I99-I117 HydrophobicContact CG2-CG2 4.26Å; T101-I117 HydrophobicContact CG2-CG2 4.31Å; R106-I117 HydrophobicContact CB-CD1 4.4Å; R106-I117 HydrophobicContact CG-CD1 3.46Å; R106-I117 VanDerWaalsContact CG-CD1 3.46Å; L110-I117 HydrophobicContact CD1-CD1 4.24Å; K112-I117 HydrophobicContact CB-CD1 4.31Å; K112-I117 HydrophobicContact CB-CG1 4.02Å; T113-I117 WeakPolarHBondContact O-CG1 3.23Å; T113-I117 PolarHBondContact O-N 2.84Å; K114-I117 PolarHBondContact O-N 3.39Å; E115-I117 PolarHBondContact O-N 3Å; I117-D119 VanDerWaalsContact C-N 3.31Å; I117-D119 PolarHBondContact O-N 3.15Å; I117-I120 PolarHBondContact O-N 3.44Å; I117-I121 HydrophobicContact CG2-CD1 3.81Å; I117-I121 HydrophobicContact CG2-CG1 4.42Å; I117-I121 WeakPolarHBondContact O-CD1 3.25Å; I117-I121 VanDerWaalsContact O-CG1 3.23Å; I117-I121 WeakPolarHBondContact O-CG1 3.07Å; I117-I121 PolarHBondContact O-N 3.45Å; I117-Y149 WeakPolarHBondContact CB-OH 3.35Å
118L98.7Very high97.9Very high29 Ų2967.3 Ų67.315%0.15231%0.314CS..Hα-helixtrans-61.2-40.4175.6-62.3177.1000111.5K114 E115 I121 K122 Y149 V153 T156K114-L118 WeakPolarHBondContact O-CG 3.35Å; K114-L118 PolarHBondContact O-N 3.42Å; K114-L118 VanDerWaalsContact O-N 3.16Å; E115-L118 PolarHBondContact O-N 2.88Å; E115-L118 VanDerWaalsContact O-N 3.12Å; L118-I121 HydrophobicContact CD2-CD1 4.49Å; L118-I121 PolarHBondContact O-N 3.03Å; L118-K122 WeakPolarHBondContact O-CB 3.16Å; L118-K122 PolarHBondContact O-N 3.41Å; L118-Y149 HydrophobicContact CD1-CE2 4.3Å; L118-Y149 HydrophobicContact CD2-CE2 4.14Å; L118-Y149 HydrophobicContact CG-CE2 4.19Å; L118-V153 HydrophobicContact CD2-CB 4.36Å; L118-V153 HydrophobicContact CD2-CG2 3.78Å; L118-T156 HydrophobicContact CB-CG2 4.38Å; L118-T156 WeakPolarHBondContact O-CG2 3.41Å
119D98.6Very high98Very high107 Ų10763.8 Ų63.857%0.57230%0.3SS*.Hα-helixtrans-63.3-42.1175.3-76.2-23.1000111.9E115 I117 K122 E123E115-D119 PolarHBondContact O-N 2.95Å; I117-D119 VanDerWaalsContact C-N 3.31Å; I117-D119 PolarHBondContact O-N 3.15Å; D119-K122 PolarHBondContact O-N 3.13Å; D119-E123 WeakPolarHBondContact O-CB 3.4Å; D119-E123 PolarHBondContact O-N 2.78Å
120I98.5Very high98.2Very high28 Ų2862.9 Ų62.914%0.14431%0.307CS..Hα-helixtrans-62.5-45175.9-71.6164.4000111.1I99 K112 E116 I117 E123 H124I99-I120 HydrophobicContact CD1-CB 4.21Å; I99-I120 HydrophobicContact CD1-CD1 4.14Å; I99-I120 HydrophobicContact CD1-CG2 3.64Å; K112-I120 HydrophobicContact CD-CD1 3.47Å; K112-I120 VanDerWaalsContact CD-CD1 3.47Å; E116-I120 WeakPolarHBondContact O-CD1 3.34Å; E116-I120 VanDerWaalsContact O-CG1 3.23Å; E116-I120 WeakPolarHBondContact O-CG1 3.23Å; E116-I120 PolarHBondContact O-N 3.29Å; I117-I120 PolarHBondContact O-N 3.44Å; I120-E123 PolarHBondContact O-N 3.2Å; I120-H124 WeakPolarHBondContact O-CB 3.34Å; I120-H124 PolarHBondContact O-N 2.87Å; I120-H124 PolarHBondContact O-ND1 3.29Å
121I98.7Very high98.3Very high0 Ų063.3 Ų63.30%031%0.307CS..Hα-helixtrans-59.3-51.5177.2-67.5163.5000109.3I99 I117 L118 E123 H124 V125 F137 V153 T156 A157I99-I121 HydrophobicContact CG2-CD1 4.08Å; I99-I121 HydrophobicContact CG2-CG1 3.72Å; I117-I121 HydrophobicContact CG2-CD1 3.81Å; I117-I121 HydrophobicContact CG2-CG1 4.42Å; I117-I121 WeakPolarHBondContact O-CD1 3.25Å; I117-I121 VanDerWaalsContact O-CG1 3.23Å; I117-I121 WeakPolarHBondContact O-CG1 3.07Å; I117-I121 PolarHBondContact O-N 3.45Å; L118-I121 HydrophobicContact CD2-CD1 4.49Å; L118-I121 PolarHBondContact O-N 3.03Å; I121-E123 VanDerWaalsContact C-N 3.33Å; I121-E123 PolarHBondContact O-N 2.89Å; I121-H124 PolarHBondContact O-N 2.64Å; I121-V125 HydrophobicContact CG2-CG2 3.96Å; I121-V125 VanDerWaalsContact O-CB 3.24Å; I121-V125 WeakPolarHBondContact O-CB 3.33Å; I121-V125 VanDerWaalsContact O-CG2 3.3Å; I121-V125 WeakPolarHBondContact O-CG2 3.45Å; I121-V125 PolarHBondContact O-N 3.03Å; I121-F137 HydrophobicContact CB-CE2 4.45Å; I121-F137 HydrophobicContact CB-CZ 4.5Å; I121-F137 HydrophobicContact CD1-CE1 4.38Å; I121-F137 HydrophobicContact CD1-CE2 4.34Å; I121-F137 HydrophobicContact CD1-CZ 3.65Å; I121-F137 HydrophobicContact CG1-CE2 3.78Å; I121-F137 HydrophobicContact CG1-CZ 3.62Å; I121-F137 HydrophobicContact CG2-CD2 4.46Å; I121-F137 HydrophobicContact CG2-CE2 4.03Å; I121-F137 HydrophobicContact CG2-CZ 4.08Å; I121-V153 HydrophobicContact CD1-CB 4.23Å; I121-V153 HydrophobicContact CD1-CG1 3.51Å; I121-V153 HydrophobicContact CD1-CG2 4.19Å; I121-T156 HydrophobicContact CB-CG2 4.26Å; I121-T156 HydrophobicContact CG2-CG2 4.02Å; I121-A157 HydrophobicContact CG2-CB 3.79Å
122K98.7Very high98.3Very high130 Ų13055.4 Ų55.457%0.56527%0.272SS*.Hα-helixtrans-56.1-47.7179.1-176.7177.7179.9177.50111.4L118 D119 T126 T156L118-K122 WeakPolarHBondContact O-CB 3.16Å; L118-K122 PolarHBondContact O-N 3.41Å; D119-K122 PolarHBondContact O-N 3.13Å; K122-T126 WeakPolarHBondContact O-CB 3.41Å; K122-T126 PolarHBondContact O-N 3.47Å; K122-T126 PolarHBondContact O-OG1 3.16Å; K122-T156 HydrophobicContact CB-CG2 4.08Å
123E98.7Very high98.3Very high92 Ų9258 Ų5843%0.4329%0.29SS..Hα-helixtrans-62.1-52.2179.6-179.3178.3-175.600112K77 D119 I120 I121 Y127K77-E123 WeakPolarHBondContact CE-OE1 3.28Å; K77-E123 IonicContact NZ-OE1 3.48Å; K77-E123 PolarHBondContact NZ-OE1 3.44Å; D119-E123 WeakPolarHBondContact O-CB 3.4Å; D119-E123 PolarHBondContact O-N 2.78Å; I120-E123 PolarHBondContact O-N 3.2Å; I121-E123 VanDerWaalsContact C-N 3.33Å; I121-E123 PolarHBondContact O-N 2.89Å; E123-Y127 WeakPolarHBondContact O-CB 3.38Å; E123-Y127 PolarHBondContact O-N 3.4Å
124H98.7Very high98.4Very high16 Ų1656.5 Ų56.57%0.07428%0.28CS..Hα-helixtrans-83.7-33.5-166.6-66.986.6000113S75 V76 I80 V97 I120 I121 Y127 A128S75-H124 PolarHBondContact O-CD2 3.05Å; S75-H124 PolarHBondContact O-CE1 2.77Å; S75-H124 PolarHBondContact O-NE2 3.33Å; V76-H124 VanDerWaalsContact CA-CD2 3.4Å; V76-H124 WeakPolarHBondContact CA-CD2 3.44Å; V76-H124 WeakPolarHBondContact CA-NE2 3.44Å; V76-H124 PolarHBondContact N-CD2 3.14Å; I80-H124 HydrophobicContact CD1-CB 4.09Å; I80-H124 WeakPolarHBondContact CD1-O 3.38Å; V97-H124 HydrophobicContact CG1-CB 4.42Å; I120-H124 WeakPolarHBondContact O-CB 3.34Å; I120-H124 PolarHBondContact O-N 2.87Å; I120-H124 PolarHBondContact O-ND1 3.29Å; I121-H124 PolarHBondContact O-N 2.64Å; H124-Y127 PolarHBondContact O-N 3.49Å; H124-A128 WeakPolarHBondContact O-CB 3.47Å; H124-A128 PolarHBondContact O-N 2.87Å
125V98.8Very high98.4Very high0 Ų053.7 Ų53.70%027%0.268CS..Hα-helixtrans-68.2-41.2171.4177.90000110.3I121 Y127 A128 R129 V135 F137 A157 A160 A162I121-V125 HydrophobicContact CG2-CG2 3.96Å; I121-V125 VanDerWaalsContact O-CB 3.24Å; I121-V125 WeakPolarHBondContact O-CB 3.33Å; I121-V125 VanDerWaalsContact O-CG2 3.3Å; I121-V125 WeakPolarHBondContact O-CG2 3.45Å; I121-V125 PolarHBondContact O-N 3.03Å; V125-Y127 VanDerWaalsContact C-N 3.31Å; V125-Y127 PolarHBondContact O-N 3.15Å; V125-A128 PolarHBondContact O-N 3.06Å; V125-R129 WeakPolarHBondContact O-CB 3.32Å; V125-R129 PolarHBondContact O-N 2.88Å; V125-V135 HydrophobicContact CG1-CG1 4.2Å; V125-F137 HydrophobicContact CG2-CB 4.4Å; V125-F137 HydrophobicContact CG2-CD2 3.67Å; V125-F137 HydrophobicContact CG2-CE2 4.34Å; V125-F137 HydrophobicContact CG2-CG 4.23Å; V125-A157 HydrophobicContact CG2-CB 4.46Å; V125-A160 HydrophobicContact CB-CB 3.8Å; V125-A160 HydrophobicContact CG1-CB 3.8Å; V125-A162 HydrophobicContact CG1-CB 4.01Å
126T98.7Very high98.4Very high69 Ų6948 Ų4842%0.42324%0.241SC..Hα-helixtrans-60.9-42.4173.2-59.20000111K122 R129 S130 A160K122-T126 WeakPolarHBondContact O-CB 3.41Å; K122-T126 PolarHBondContact O-N 3.47Å; K122-T126 PolarHBondContact O-OG1 3.16Å; T126-R129 PolarHBondContact O-N 2.76Å; T126-S130 PolarHBondContact O-N 3.33Å; T126-A160 WeakPolarHBondContact CA-O 3.16Å
127Y98.7Very high98.4Very high55 Ų5544.2 Ų44.222%0.21622%0.224CC..Hα-helixtrans-64.9-44.7177.7-173.7-108.4000112.2K77 I80 D81 E123 H124 V125 R129 S130 K131K77-Y127 HydrophobicContact CB-CD1 4.15Å; K77-Y127 HydrophobicContact CB-CE1 3.79Å; K77-Y127 HydrophobicContact CD-CD2 4.42Å; K77-Y127 HydrophobicContact CD-CE1 4.47Å; K77-Y127 HydrophobicContact CD-CE2 4.38Å; K77-Y127 HydrophobicContact CD-CG 4.48Å; K77-Y127 HydrophobicContact CG-CD1 3.72Å; K77-Y127 HydrophobicContact CG-CD2 4.44Å; K77-Y127 HydrophobicContact CG-CE1 3.8Å; K77-Y127 HydrophobicContact CG-CG 4.05Å; I80-Y127 HydrophobicContact CB-CD1 4.08Å; I80-Y127 HydrophobicContact CB-CE1 4.2Å; I80-Y127 HydrophobicContact CD1-CD1 3.9Å; I80-Y127 HydrophobicContact CG2-CD1 3.82Å; I80-Y127 HydrophobicContact CG2-CE1 4.01Å; D81-Y127 WeakPolarHBondContact OD1-CE1 3.1Å; D81-Y127 PolarHBondContact OD1-OH 3.27Å; D81-Y127 PolarHBondContact OD2-OH 3.02Å; E123-Y127 WeakPolarHBondContact O-CB 3.38Å; E123-Y127 PolarHBondContact O-N 3.4Å; H124-Y127 PolarHBondContact O-N 3.49Å; V125-Y127 VanDerWaalsContact C-N 3.31Å; V125-Y127 PolarHBondContact O-N 3.15Å; Y127-R129 VanDerWaalsContact C-N 3.33Å; Y127-R129 PolarHBondContact O-N 3.11Å; Y127-S130 WeakPolarHBondContact O-CB 3.4Å; Y127-S130 PolarHBondContact O-N 3.38Å; Y127-S130 VanDerWaalsContact O-N 3.16Å; Y127-S130 PolarHBondContact O-OG 2.95Å; Y127-K131 HydrophobicContact CE1-CD 4.47Å; Y127-K131 VanDerWaalsContact OH-CE 3.29Å; Y127-K131 WeakPolarHBondContact OH-CE 3.38Å; Y127-K131 PolarHBondContact OH-NZ 3.04Å
128A98.7Very high98.5Very high0 Ų044.4 Ų44.40%023%0.225CC..Hα-helixtrans-59.6-43.4173.800000111.5I80 V97 H124 V125 S130 K131 F132 V135I80-A128 HydrophobicContact CD1-CB 4.24Å; I80-A128 HydrophobicContact CG2-CB 4.11Å; V97-A128 HydrophobicContact CG2-CB 3.82Å; H124-A128 WeakPolarHBondContact O-CB 3.47Å; H124-A128 PolarHBondContact O-N 2.87Å; V125-A128 PolarHBondContact O-N 3.06Å; A128-S130 PolarHBondContact O-N 2.77Å; A128-K131 CarbonylContact O-C 3.59Å; A128-K131 WeakPolarHBondContact O-CA 3.24Å; A128-K131 PolarHBondContact O-N 3.39Å; A128-F132 PolarHBondContact O-N 2.87Å; A128-V135 HydrophobicContact CB-CG1 4Å; A128-V135 HydrophobicContact CB-CG2 3.97Å
129R98.2Very high98.5Very high85 Ų8543 Ų4332%0.32122%0.218SC..Hα-helixtrans-62.1-28.2177.2-178.266.3-148.6-172.412.9113.1V125 T126 Y127 K131 D133 V135 G161V125-R129 WeakPolarHBondContact O-CB 3.32Å; V125-R129 PolarHBondContact O-N 2.88Å; T126-R129 PolarHBondContact O-N 2.76Å; Y127-R129 VanDerWaalsContact C-N 3.33Å; Y127-R129 PolarHBondContact O-N 3.11Å; R129-K131 PolarHBondContact O-N 3.35Å; R129-D133 VanDerWaalsContact CZ-O 3.3Å; R129-D133 PolarHBondContact NH1-O 3.35Å; R129-D133 PolarHBondContact NH2-O 3.21Å; R129-D133 IonicContact NH2-OD1 2.78Å; R129-D133 PolarHBondContact NH2-OD1 3.18Å; R129-V135 HydrophobicContact CB-CG2 4.33Å; R129-G161 WeakPolarHBondContact CD-O 3.4Å
130S98.1Very high98.4Very high86 Ų8639.9 Ų39.960%0.60120%0.2SC*.THydrogen-bonded Turntrans-69.4-15.8173.980.20000113.7T126 Y127 A128T126-S130 PolarHBondContact O-N 3.33Å; Y127-S130 WeakPolarHBondContact O-CB 3.4Å; Y127-S130 PolarHBondContact O-N 3.38Å; Y127-S130 VanDerWaalsContact O-N 3.16Å; Y127-S130 PolarHBondContact O-OG 2.95Å; A128-S130 PolarHBondContact O-N 2.77Å
131K97.8Very high98.4Very high60 Ų6038.5 Ų38.526%0.26119%0.193SC..THydrogen-bonded Turntrans-113-25.7-177.5-64.8-158.1171.5-155.60114I80 D81 Y84 Y127 A128 R129I80-K131 HydrophobicContact CG2-CD 4.5Å; D81-K131 WeakPolarHBondContact OD1-CE 3.43Å; D81-K131 IonicContact OD1-NZ 3.78Å; D81-K131 PolarHBondContact OD1-NZ 2.86Å; Y84-K131 HydrophobicContact CD1-CD 4.27Å; Y84-K131 HydrophobicContact CD2-CB 3.7Å; Y84-K131 HydrophobicContact CD2-CD 4.07Å; Y84-K131 HydrophobicContact CD2-CG 4.33Å; Y84-K131 HydrophobicContact CE2-CB 4.13Å; Y84-K131 WeakPolarHBondContact CE2-O 3.28Å; Y84-K131 HydrophobicContact CG-CB 4.3Å; Y84-K131 HydrophobicContact CG-CD 3.82Å; Y127-K131 HydrophobicContact CE1-CD 4.47Å; Y127-K131 VanDerWaalsContact OH-CE 3.29Å; Y127-K131 WeakPolarHBondContact OH-CE 3.38Å; Y127-K131 PolarHBondContact OH-NZ 3.04Å; A128-K131 CarbonylContact O-C 3.59Å; A128-K131 WeakPolarHBondContact O-CA 3.24Å; A128-K131 PolarHBondContact O-N 3.39Å; R129-K131 PolarHBondContact O-N 3.35Å
132F98Very high98.3Very high4 Ų438.5 Ų38.52%0.01819%0.193CC..  trans-131.1139.3-174.8-63.3-90.5000111.5I80 C83 Y84 L87 C95 A128 V134 V135I80-F132 HydrophobicContact CG2-CE2 4.45Å; C83-F132 HydrophobicContact CB-CZ 4.18Å; Y84-F132 VanDerWaalsContact CA-CZ 3.43Å; Y84-F132 HydrophobicContact CD2-CE2 4.22Å; Y84-F132 HydrophobicContact CD2-CZ 4.17Å; L87-F132 HydrophobicContact CB-CE1 4.34Å; L87-F132 HydrophobicContact CD1-CE1 3.72Å; L87-F132 HydrophobicContact CD1-CZ 4.04Å; C95-F132 HydrophobicContact CB-CB 4.4Å; C95-F132 HydrophobicContact CB-CD1 4.19Å; C95-F132 HydrophobicContact CB-CD2 3.43Å; C95-F132 VanDerWaalsContact CB-CD2 3.43Å; C95-F132 HydrophobicContact CB-CE1 4.26Å; C95-F132 HydrophobicContact CB-CE2 3.53Å; C95-F132 HydrophobicContact CB-CG 3.76Å; C95-F132 HydrophobicContact CB-CZ 3.92Å; A128-F132 PolarHBondContact O-N 2.87Å; F132-V134 VanDerWaalsContact C-N 3.29Å; F132-V135 HydrophobicContact CB-CG2 4.1Å
133D96.7Very high98.3Very high130 Ų13032.8 Ų32.870%0.69517%0.169SC*.SBendtrans-76.6-17.6172.4-75.9-37.4000113.3R129R129-D133 VanDerWaalsContact CZ-O 3.3Å; R129-D133 PolarHBondContact NH1-O 3.35Å; R129-D133 PolarHBondContact NH2-O 3.21Å; R129-D133 IonicContact NH2-OD1 2.78Å; R129-D133 PolarHBondContact NH2-OD1 3.18Å
134V98.1Very high98.2Very high37 Ų3732.7 Ų32.722%0.22417%0.165CC..  trans-127.3116.8177.5178.50000108.5Q94 C95 F132 Y164Q94-V134 WeakPolarHBondContact CA-O 3.41Å; Q94-V134 HydrophobicContact CB-CB 4.33Å; Q94-V134 HydrophobicContact CB-CG1 4.05Å; Q94-V134 HydrophobicContact CG-CB 3.91Å; Q94-V134 HydrophobicContact CG-CG1 3.64Å; C95-V134 PolarHBondContact N-O 2.92Å; F132-V134 VanDerWaalsContact C-N 3.29Å; V134-Y164 HydrophobicContact CG1-CD2 3.57Å; V134-Y164 HydrophobicContact CG1-CE2 3.47Å; V134-Y164 VanDerWaalsContact CG1-CE2 3.47Å
135V98.6Very high98.2Very high0 Ų032.5 Ų32.50%017%0.165CC..EExtended strand (participates in β ladder)trans-124.7125.2178.1178.90000108.4C95 V125 A128 R129 F132 T163 Y164C95-V135 WeakPolarHBondContact O-CA 3.38Å; V125-V135 HydrophobicContact CG1-CG1 4.2Å; A128-V135 HydrophobicContact CB-CG1 4Å; A128-V135 HydrophobicContact CB-CG2 3.97Å; R129-V135 HydrophobicContact CB-CG2 4.33Å; F132-V135 HydrophobicContact CB-CG2 4.1Å; V135-T163 PolarHBondContact N-OG1 3.5Å; V135-T163 PolarHBondContact O-N 2.85Å; V135-T163 PolarHBondContact O-OG1 2.88Å; V135-Y164 PolarHBondContact O-N 3.11Å; V135-Y164 VanDerWaalsContact O-N 3.14Å
136E98.8Very high98.1Very high0 Ų035.4 Ų35.40%018%0.178CC..EExtended strand (participates in β ladder)trans-100.1138.3171.3-171.6164.390.100109.4C95 H96 V97 Y164 N166 R223C95-E136 PolarHBondContact O-N 3.32Å; H96-E136 WeakPolarHBondContact CA-O 3.41Å; H96-E136 HydrophobicContact CB-CB 4.29Å; H96-E136 IonicContact CE1-OE1 2.83Å; H96-E136 IonicContact CG-OE1 3.55Å; H96-E136 IonicContact ND1-OE1 2.8Å; V97-E136 PolarHBondContact N-O 3.19Å; E136-Y164 WeakPolarHBondContact CA-O 3.09Å; E136-Y164 WeakPolarHBondContact OE2-CB 3.28Å; E136-N166 HydrophobicContact CG-CB 4.23Å; E136-R223 IonicContact OE2-CZ 3.01Å; E136-R223 IonicContact OE2-NH1 2.72Å; E136-R223 PolarHBondContact OE2-NH1 3.3Å
137F98.9Very high98.1Very high0 Ų035.5 Ų35.50%018%0.175CC..EExtended strand (participates in β ladder)trans-123.4133.3175.7175.7-97000111.8V97 I99 I121 V125 P139 V153 A157 A162 Y164 I165 N166V97-F137 VanDerWaalsContact O-CA 3.27Å; V97-F137 WeakPolarHBondContact O-CA 3.46Å; V97-F137 WeakPolarHBondContact O-CD2 3.32Å; I99-F137 HydrophobicContact CG2-CE2 3.99Å; I99-F137 HydrophobicContact CG2-CZ 3.92Å; I121-F137 HydrophobicContact CB-CE2 4.45Å; I121-F137 HydrophobicContact CB-CZ 4.5Å; I121-F137 HydrophobicContact CD1-CE1 4.38Å; I121-F137 HydrophobicContact CD1-CE2 4.34Å; I121-F137 HydrophobicContact CD1-CZ 3.65Å; I121-F137 HydrophobicContact CG1-CE2 3.78Å; I121-F137 HydrophobicContact CG1-CZ 3.62Å; I121-F137 HydrophobicContact CG2-CD2 4.46Å; I121-F137 HydrophobicContact CG2-CE2 4.03Å; I121-F137 HydrophobicContact CG2-CZ 4.08Å; V125-F137 HydrophobicContact CG2-CB 4.4Å; V125-F137 HydrophobicContact CG2-CD2 3.67Å; V125-F137 HydrophobicContact CG2-CE2 4.34Å; V125-F137 HydrophobicContact CG2-CG 4.23Å; F137-P139 HydrophobicContact CE1-CB 4.3Å; F137-P139 HydrophobicContact CE1-CG 4.26Å; F137-V153 HydrophobicContact CE1-CG1 3.58Å; F137-V153 HydrophobicContact CZ-CG1 3.92Å; F137-A157 HydrophobicContact CB-CB 3.9Å; F137-A157 HydrophobicContact CD1-CB 3.36Å; F137-A157 HydrophobicContact CD2-CB 4.29Å; F137-A157 HydrophobicContact CE1-CB 3.95Å; F137-A157 HydrophobicContact CG-CB 3.55Å; F137-A162 HydrophobicContact CB-CB 4.11Å; F137-Y164 PolarHBondContact N-O 3.33Å; F137-I165 HydrophobicContact CB-CD1 4.26Å; F137-I165 HydrophobicContact CD1-CD1 4.49Å; F137-N166 PolarHBondContact O-N 3.37Å
138S98.8Very high98Very high5 Ų537.3 Ų37.34%0.03519%0.189CC..EExtended strand (participates in β ladder)trans-116.9121.9173.1-70.10000112.7H96 V97 F98 I99 E140 N166H96-S138 PolarHBondContact CE1-OG 3.28Å; H96-S138 WeakPolarHBondContact NE2-CB 3.48Å; H96-S138 PolarHBondContact NE2-OG 3.01Å; V97-S138 PolarHBondContact O-N 2.84Å; F98-S138 VanDerWaalsContact CA-O 3.3Å; F98-S138 WeakPolarHBondContact CA-O 3.42Å; F98-S138 WeakPolarHBondContact CB-O 3.06Å; I99-S138 PolarHBondContact N-O 3.46Å; I99-S138 VanDerWaalsContact N-O 3.17Å; S138-E140 PolarHBondContact O-N 2.83Å; S138-N166 VanDerWaalsContact OG-CB 3.26Å; S138-N166 WeakPolarHBondContact OG-CB 3.22Å; S138-N166 PolarHBondContact OG-ND2 3.01Å
139P98.5Very high98Very high0 Ų037.4 Ų37.40%019%0.189CC..EExtended strand (participates in β ladder)trans-73.895.715520-7.2000108.8I99 T101 F137 D141 A142 L150 V153 N166 I167 P168I99-P139 CarbonylContact O-C 3.6Å; I99-P139 WeakPolarHBondContact O-CA 3.18Å; T101-P139 HydrophobicContact CG2-CB 3.68Å; T101-P139 WeakPolarHBondContact OG1-CB 3.14Å; F137-P139 HydrophobicContact CE1-CB 4.3Å; F137-P139 HydrophobicContact CE1-CG 4.26Å; P139-D141 PolarHBondContact O-N 3.49Å; P139-A142 HydrophobicContact CB-CB 4.27Å; P139-A142 HydrophobicContact CG-CB 4.04Å; P139-A142 VanDerWaalsContact O-CB 3.3Å; P139-A142 WeakPolarHBondContact O-CB 3.48Å; P139-A142 PolarHBondContact O-N 2.87Å; P139-A142 VanDerWaalsContact O-N 3.11Å; P139-L150 HydrophobicContact CB-CD1 3.82Å; P139-L150 HydrophobicContact CG-CD1 3.57Å; P139-V153 HydrophobicContact CB-CG1 4Å; P139-V153 HydrophobicContact CG-CG1 4.46Å; P139-N166 WeakPolarHBondContact CD-O 3.26Å; P139-I167 HydrophobicContact CG-CD1 4.06Å; P139-P168 WeakPolarHBondContact O-CD 3.44Å; P139-P168 WeakPolarHBondContact O-CG 3.27Å
140E98.2Very high98Very high40 Ų4033.4 Ų33.419%0.18717%0.174CC..EExtended strand (participates in β ladder)trans-57.5133.5176.7170.8-165.9-162.100109.4F98 I99 A100 T101 K109 S138 T170F98-E140 HydrophobicContact CD2-CB 4.17Å; I99-E140 PolarHBondContact O-N 3.42Å; A100-E140 WeakPolarHBondContact CA-O 3.37Å; A100-E140 HydrophobicContact CB-CB 4.25Å; A100-E140 HydrophobicContact CB-CG 4.3Å; A100-E140 WeakPolarHBondContact CB-OE2 3.28Å; T101-E140 PolarHBondContact N-O 2.86Å; K109-E140 IonicContact NZ-OE1 3.76Å; K109-E140 PolarHBondContact NZ-OE1 3.36Å; K109-E140 IonicContact NZ-OE2 2.8Å; K109-E140 PolarHBondContact NZ-OE2 3.05Å; S138-E140 PolarHBondContact O-N 2.83Å; E140-T170 HydrophobicContact CG-CG2 4.44Å
141D97.3Very high98.1Very high0 Ų030.7 Ų30.70%015%0.153CC..THydrogen-bonded Turntrans6439.5-173.1-15933000113.9S102 H105 P139 T143 R144 T145 T170S102-D141 WeakPolarHBondContact CB-OD2 3.4Å; S102-D141 PolarHBondContact OG-OD2 3.45Å; H105-D141 VanDerWaalsContact CD2-CB 3.49Å; H105-D141 WeakPolarHBondContact CD2-CB 3.3Å; H105-D141 IonicContact CD2-OD2 2.67Å; H105-D141 PolarHBondContact CD2-OD2 2.81Å; H105-D141 VanDerWaalsContact CD2-OD2 3.23Å; H105-D141 IonicContact NE2-OD2 2.8Å; P139-D141 PolarHBondContact O-N 3.49Å; D141-T143 VanDerWaalsContact C-N 3.3Å; D141-T143 PolarHBondContact O-N 3.01Å; D141-R144 VanDerWaalsContact CG-NE 3.27Å; D141-R144 PolarHBondContact O-N 3.22Å; D141-R144 IonicContact OD1-CZ 2.77Å; D141-R144 IonicContact OD1-NE 3.11Å; D141-R144 PolarHBondContact OD1-NE 3.25Å; D141-R144 IonicContact OD1-NH2 2.57Å; D141-R144 PolarHBondContact OD1-NH2 3.45Å; D141-R144 VanDerWaalsContact OD1-NH2 3.09Å; D141-R144 IonicContact OD2-CZ 2.69Å; D141-R144 IonicContact OD2-NE 2.79Å; D141-R144 PolarHBondContact OD2-NE 3.25Å; D141-R144 IonicContact OD2-NH2 2.65Å; D141-R144 PolarHBondContact OD2-NH2 2.9Å; D141-T145 PolarHBondContact O-N 3Å; D141-T145 PolarHBondContact O-OG1 2.86Å; D141-T145 VanDerWaalsContact O-OG1 3.1Å; D141-T170 WeakPolarHBondContact CA-OG1 3.29Å; D141-T170 PolarHBondContact N-OG1 3.26Å
142A98.1Very high98.1Very high0 Ų032.5 Ų32.50%016%0.162CC..G310 helixtrans-57-39.8-177.300000113.1P139 R144 T145 L150 I167 P168P139-A142 HydrophobicContact CB-CB 4.27Å; P139-A142 HydrophobicContact CG-CB 4.04Å; P139-A142 VanDerWaalsContact O-CB 3.3Å; P139-A142 WeakPolarHBondContact O-CB 3.48Å; P139-A142 PolarHBondContact O-N 2.87Å; P139-A142 VanDerWaalsContact O-N 3.11Å; A142-R144 PolarHBondContact O-N 3.38Å; A142-R144 VanDerWaalsContact O-N 3.15Å; A142-T145 VanDerWaalsContact O-CB 3.28Å; A142-T145 WeakPolarHBondContact O-CB 3.45Å; A142-T145 PolarHBondContact O-N 2.78Å; A142-L150 HydrophobicContact CB-CD1 4.02Å; A142-L150 HydrophobicContact CB-CD2 4.33Å; A142-I167 HydrophobicContact CB-CG2 3.78Å; A142-P168 HydrophobicContact CB-CG 4.41Å; A142-P168 PolarHBondContact N-O 3.22Å
143T97.3Very high98.2Very high10 Ų1032.3 Ų32.36%0.06116%0.161CC..G310 helixtrans-65-18-177.5520000113.9D141 D169 T174 Y179 I182D141-T143 VanDerWaalsContact C-N 3.3Å; D141-T143 PolarHBondContact O-N 3.01Å; T143-D169 HydrophobicContact CG2-CB 3.66Å; T143-D169 PolarHBondContact OG1-OD1 3.4Å; T143-T174 HydrophobicContact CG2-CG2 4.09Å; T143-Y179 HydrophobicContact CG2-CD2 3.63Å; T143-Y179 HydrophobicContact CG2-CE2 3.63Å; T143-I182 HydrophobicContact CG2-CD1 4.35Å
144R97.1Very high98.3Very high90 Ų9026.1 Ų26.134%0.3413%0.128SC..G310 helixtrans-104.25172.7-62.1-170-62.8179.21.7113.5P103 D141 A142 F173P103-R144 WeakPolarHBondContact CD-O 3.39Å; D141-R144 VanDerWaalsContact CG-NE 3.27Å; D141-R144 PolarHBondContact O-N 3.22Å; D141-R144 IonicContact OD1-CZ 2.77Å; D141-R144 IonicContact OD1-NE 3.11Å; D141-R144 PolarHBondContact OD1-NE 3.25Å; D141-R144 IonicContact OD1-NH2 2.57Å; D141-R144 PolarHBondContact OD1-NH2 3.45Å; D141-R144 VanDerWaalsContact OD1-NH2 3.09Å; D141-R144 IonicContact OD2-CZ 2.69Å; D141-R144 IonicContact OD2-NE 2.79Å; D141-R144 PolarHBondContact OD2-NE 3.25Å; D141-R144 IonicContact OD2-NH2 2.65Å; D141-R144 PolarHBondContact OD2-NH2 2.9Å; A142-R144 PolarHBondContact O-N 3.38Å; A142-R144 VanDerWaalsContact O-N 3.15Å; R144-F173 HydrophobicContact CG-CD1 4.19Å; R144-F173 HydrophobicContact CG-CE1 3.22Å; R144-F173 HydrophobicContact CG-CE2 4.46Å; R144-F173 HydrophobicContact CG-CZ 3.4Å; R144-F173 VanDerWaalsContact CG-CZ 3.4Å
145T98.1Very high98.3Very high12 Ų1226 Ų267%0.07413%0.125CC..SBendtrans-85.1137.7175.5-57.30000109.7T101 S102 D141 A142 L147 Y149 L150T101-T145 PolarHBondContact OG1-OG1 3.39Å; S102-T145 WeakPolarHBondContact CA-OG1 3.41Å; S102-T145 PolarHBondContact N-OG1 3.35Å; D141-T145 PolarHBondContact O-N 3Å; D141-T145 PolarHBondContact O-OG1 2.86Å; D141-T145 VanDerWaalsContact O-OG1 3.1Å; A142-T145 VanDerWaalsContact O-CB 3.28Å; A142-T145 WeakPolarHBondContact O-CB 3.45Å; A142-T145 PolarHBondContact O-N 2.78Å; T145-L147 PolarHBondContact O-N 2.87Å; T145-Y149 HydrophobicContact CG2-CD1 3.74Å; T145-Y149 HydrophobicContact CG2-CE1 4.43Å; T145-L150 HydrophobicContact CG2-CB 3.96Å; T145-L150 HydrophobicContact CG2-CD1 4.4Å
146E97.9Very high98.3Very high61 Ų6127.4 Ų27.429%0.28513%0.134SC..  trans-58.9128177.9-4997120.600110P103 R106 K114 D148 Y149 L150P103-E146 HydrophobicContact CG-CG 4.37Å; P103-E146 WeakPolarHBondContact CG-OE2 3.15Å; R106-E146 IonicContact CZ-OE1 3.64Å; R106-E146 IonicContact CZ-OE2 2.87Å; R106-E146 IonicContact NH1-OE1 2.86Å; R106-E146 IonicContact NH1-OE2 2.75Å; R106-E146 PolarHBondContact NH1-OE2 3.39Å; R106-E146 IonicContact NH2-OE1 3.91Å; R106-E146 PolarHBondContact NH2-OE1 3.47Å; R106-E146 IonicContact NH2-OE2 2.6Å; R106-E146 PolarHBondContact NH2-OE2 2.94Å; K114-E146 WeakPolarHBondContact CE-OE1 3.16Å; K114-E146 IonicContact NZ-OE1 2.7Å; K114-E146 PolarHBondContact NZ-OE1 3.23Å; K114-E146 IonicContact NZ-OE2 2.62Å; E146-D148 VanDerWaalsContact C-N 3.27Å; E146-D148 VanDerWaalsContact CB-OD1 3.31Å; E146-D148 WeakPolarHBondContact CB-OD1 3.41Å; E146-D148 PolarHBondContact O-N 3.13Å; E146-D148 VanDerWaalsContact O-N 3.17Å; E146-Y149 CarbonylContact O-C 3.5Å; E146-Y149 WeakPolarHBondContact O-CA 3.26Å; E146-Y149 PolarHBondContact O-N 3.37Å; E146-L150 PolarHBondContact O-N 2.78Å
147L97.6Very high98.3Very high70 Ų7027.4 Ų27.437%0.36613%0.134SC..Hα-helixtrans-57.5-36.9-166.5-174.861.9000113.9T145 L150 L151 I182 Y185T145-L147 PolarHBondContact O-N 2.87Å; L147-L150 PolarHBondContact O-N 3.06Å; L147-L151 PolarHBondContact O-N 3.33Å; L147-I182 HydrophobicContact CD1-CG1 4.34Å; L147-I182 HydrophobicContact CD1-CG2 4.5Å; L147-Y185 HydrophobicContact CD1-CD1 3.53Å; L147-Y185 HydrophobicContact CD1-CE1 4.04Å; L147-Y185 HydrophobicContact CD1-CG 4.2Å; L147-Y185 HydrophobicContact CD2-CD1 3.83Å; L147-Y185 HydrophobicContact CD2-CD2 4.24Å; L147-Y185 HydrophobicContact CD2-CE1 4.07Å; L147-Y185 HydrophobicContact CD2-CE2 4.48Å; L147-Y185 HydrophobicContact CD2-CG 3.9Å; L147-Y185 HydrophobicContact CG-CD1 3.56Å; L147-Y185 HydrophobicContact CG-CE1 3.62Å; L147-Y185 HydrophobicContact CG-CG 4.17Å
148D98Very high98.3Very high94 Ų9427.4 Ų27.450%0.50313%0.134SC..Hα-helixtrans-67.8-3617661.9-31.8000112.7E146 Q152E146-D148 VanDerWaalsContact C-N 3.27Å; E146-D148 VanDerWaalsContact CB-OD1 3.31Å; E146-D148 WeakPolarHBondContact CB-OD1 3.41Å; E146-D148 PolarHBondContact O-N 3.13Å; E146-D148 VanDerWaalsContact O-N 3.17Å; D148-Q152 WeakPolarHBondContact O-CG 3.45Å; D148-Q152 PolarHBondContact O-N 2.85Å; D148-Q152 PolarHBondContact O-NE2 2.84Å
149Y98.6Very high98.3Very high1 Ų132.7 Ų32.70%0.00416%0.162CC..Hα-helixtrans-78.1-36.5174-178.3-119.3000111.8K114 I117 L118 T145 E146 L151 Q152 V153K114-Y149 VanDerWaalsContact CA-OH 3.28Å; K114-Y149 WeakPolarHBondContact CA-OH 3.47Å; K114-Y149 HydrophobicContact CB-CD2 4.11Å; K114-Y149 HydrophobicContact CB-CE2 3.44Å; K114-Y149 VanDerWaalsContact CB-CE2 3.44Å; K114-Y149 HydrophobicContact CD-CD1 4.19Å; K114-Y149 HydrophobicContact CD-CD2 3.59Å; K114-Y149 HydrophobicContact CD-CE1 4.38Å; K114-Y149 HydrophobicContact CD-CE2 3.82Å; K114-Y149 HydrophobicContact CD-CG 3.8Å; K114-Y149 HydrophobicContact CG-CD1 4.25Å; K114-Y149 HydrophobicContact CG-CD2 3.92Å; K114-Y149 HydrophobicContact CG-CE1 3.95Å; K114-Y149 HydrophobicContact CG-CE2 3.59Å; K114-Y149 HydrophobicContact CG-CG 4.24Å; K114-Y149 PolarHBondContact O-OH 2.87Å; I117-Y149 WeakPolarHBondContact CB-OH 3.35Å; L118-Y149 HydrophobicContact CD1-CE2 4.3Å; L118-Y149 HydrophobicContact CD2-CE2 4.14Å; L118-Y149 HydrophobicContact CG-CE2 4.19Å; T145-Y149 HydrophobicContact CG2-CD1 3.74Å; T145-Y149 HydrophobicContact CG2-CE1 4.43Å; E146-Y149 CarbonylContact O-C 3.5Å; E146-Y149 WeakPolarHBondContact O-CA 3.26Å; E146-Y149 PolarHBondContact O-N 3.37Å; Y149-L151 VanDerWaalsContact C-N 3.29Å; Y149-L151 PolarHBondContact O-N 2.86Å; Y149-Q152 HydrophobicContact CD2-CB 4.44Å; Y149-Q152 WeakPolarHBondContact O-CB 3.34Å; Y149-Q152 PolarHBondContact O-N 3.35Å; Y149-V153 HydrophobicContact CD1-CG2 4.29Å; Y149-V153 HydrophobicContact CD2-CG2 4.49Å; Y149-V153 HydrophobicContact CE1-CG2 3.83Å; Y149-V153 HydrophobicContact CE2-CG2 4.05Å; Y149-V153 WeakPolarHBondContact O-CG2 3.38Å; Y149-V153 PolarHBondContact O-N 3.05Å
150L98.7Very high98.3Very high1 Ų133.2 Ų33.21%0.00517%0.166CC..Hα-helixtrans-58.7-42.7173.8-177.860.4000110.9P139 A142 T145 E146 L147 Q152 V153 V154 I182 L186P139-L150 HydrophobicContact CB-CD1 3.82Å; P139-L150 HydrophobicContact CG-CD1 3.57Å; A142-L150 HydrophobicContact CB-CD1 4.02Å; A142-L150 HydrophobicContact CB-CD2 4.33Å; T145-L150 HydrophobicContact CG2-CB 3.96Å; T145-L150 HydrophobicContact CG2-CD1 4.4Å; E146-L150 PolarHBondContact O-N 2.78Å; L147-L150 PolarHBondContact O-N 3.06Å; L150-Q152 VanDerWaalsContact C-N 3.34Å; L150-Q152 PolarHBondContact O-N 3.39Å; L150-V153 PolarHBondContact O-N 3.47Å; L150-V154 HydrophobicContact CD1-CG2 4.43Å; L150-V154 WeakPolarHBondContact O-CG2 3.47Å; L150-V154 PolarHBondContact O-N 3.48Å; L150-I182 HydrophobicContact CD2-CG2 3.96Å; L150-L186 HydrophobicContact CD2-CD1 4Å; L150-L186 HydrophobicContact CD2-CD2 4.49Å; L150-L186 HydrophobicContact CG-CD1 4.26Å; L150-L186 HydrophobicContact CG-CD2 4.18Å
151L98.8Very high98.3Very high29 Ų2931.7 Ų31.715%0.15216%0.161CC..Hα-helixtrans-60.4-40.9173177.262.5000112.3L147 Y149 V154 Q155 Y185 L186 N189L147-L151 PolarHBondContact O-N 3.33Å; Y149-L151 VanDerWaalsContact C-N 3.29Å; Y149-L151 PolarHBondContact O-N 2.86Å; L151-V154 PolarHBondContact O-N 2.9Å; L151-Q155 VanDerWaalsContact O-CB 3.22Å; L151-Q155 WeakPolarHBondContact O-CB 3.47Å; L151-Q155 PolarHBondContact O-N 2.99Å; L151-Y185 HydrophobicContact CB-CE1 4.05Å; L151-Y185 HydrophobicContact CD2-CE1 3.95Å; L151-Y185 HydrophobicContact CG-CE1 4.49Å; L151-L186 HydrophobicContact CB-CD2 4.17Å; L151-L186 HydrophobicContact CD1-CD2 4.28Å; L151-N189 HydrophobicContact CD1-CB 3.86Å; L151-N189 HydrophobicContact CD2-CB 3.74Å; L151-N189 HydrophobicContact CG-CB 4.48Å
152Q98.6Very high98.3Very high98 Ų9831.7 Ų31.746%0.45816%0.161SC..Hα-helixtrans-64.3-40.3176-71.8171.767.100112.1D148 Y149 L150 T156D148-Q152 WeakPolarHBondContact O-CG 3.45Å; D148-Q152 PolarHBondContact O-N 2.85Å; D148-Q152 PolarHBondContact O-NE2 2.84Å; Y149-Q152 HydrophobicContact CD2-CB 4.44Å; Y149-Q152 WeakPolarHBondContact O-CB 3.34Å; Y149-Q152 PolarHBondContact O-N 3.35Å; L150-Q152 VanDerWaalsContact C-N 3.34Å; L150-Q152 PolarHBondContact O-N 3.39Å; Q152-T156 WeakPolarHBondContact O-CB 3.36Å; Q152-T156 PolarHBondContact O-N 3.15Å; Q152-T156 PolarHBondContact O-OG1 2.89Å
153V98.8Very high98.3Very high0 Ų032.6 Ų32.60%017%0.167CC..Hα-helixtrans-62.5-51.5175.5165.80000110.4T101 L118 I121 F137 P139 Y149 L150 Q155 T156 A157T101-V153 HydrophobicContact CG2-CB 4.49Å; T101-V153 HydrophobicContact CG2-CG1 3.86Å; T101-V153 HydrophobicContact CG2-CG2 3.97Å; L118-V153 HydrophobicContact CD2-CB 4.36Å; L118-V153 HydrophobicContact CD2-CG2 3.78Å; I121-V153 HydrophobicContact CD1-CB 4.23Å; I121-V153 HydrophobicContact CD1-CG1 3.51Å; I121-V153 HydrophobicContact CD1-CG2 4.19Å; F137-V153 HydrophobicContact CE1-CG1 3.58Å; F137-V153 HydrophobicContact CZ-CG1 3.92Å; P139-V153 HydrophobicContact CB-CG1 4Å; P139-V153 HydrophobicContact CG-CG1 4.46Å; Y149-V153 HydrophobicContact CD1-CG2 4.29Å; Y149-V153 HydrophobicContact CD2-CG2 4.49Å; Y149-V153 HydrophobicContact CE1-CG2 3.83Å; Y149-V153 HydrophobicContact CE2-CG2 4.05Å; Y149-V153 WeakPolarHBondContact O-CG2 3.38Å; Y149-V153 PolarHBondContact O-N 3.05Å; L150-V153 PolarHBondContact O-N 3.47Å; V153-Q155 PolarHBondContact O-N 3.47Å; V153-T156 PolarHBondContact O-N 3.06Å; V153-A157 PolarHBondContact O-N 3.09Å
154V98.8Very high98.4Very high0 Ų033.4 Ų33.40%017%0.169CC..Hα-helixtrans-59.7-47.9178.5169.60000110.7L150 L151 T156 A157 V158 I165 I167 L186 T190 F198L150-V154 HydrophobicContact CD1-CG2 4.43Å; L150-V154 WeakPolarHBondContact O-CG2 3.47Å; L150-V154 PolarHBondContact O-N 3.48Å; L151-V154 PolarHBondContact O-N 2.9Å; V154-T156 VanDerWaalsContact C-N 3.28Å; V154-T156 PolarHBondContact O-N 3.12Å; V154-A157 PolarHBondContact O-N 3.36Å; V154-V158 HydrophobicContact CG1-CG2 4.38Å; V154-V158 WeakPolarHBondContact O-CG2 3.34Å; V154-V158 PolarHBondContact O-N 2.63Å; V154-I165 HydrophobicContact CG1-CD1 4.38Å; V154-I165 HydrophobicContact CG1-CG1 4.2Å; V154-I165 HydrophobicContact CG1-CG2 3.95Å; V154-I165 HydrophobicContact CG2-CG2 3.9Å; V154-I167 HydrophobicContact CG2-CD1 4.02Å; V154-L186 HydrophobicContact CG2-CD1 4.33Å; V154-L186 HydrophobicContact CG2-CD2 4.21Å; V154-T190 HydrophobicContact CG1-CG2 4.04Å; V154-T190 WeakPolarHBondContact CG1-OG1 3.5Å; V154-F198 HydrophobicContact CG1-CE1 4.13Å; V154-F198 HydrophobicContact CG1-CZ 4.22Å
155Q98.8Very high98.5Very high35 Ų3529.1 Ų29.116%0.16415%0.153CC..Hα-helixtrans-58.4-41.7177.2-172.763.661.700111.4L151 V153 A157 V158 D159 K191L151-Q155 VanDerWaalsContact O-CB 3.22Å; L151-Q155 WeakPolarHBondContact O-CB 3.47Å; L151-Q155 PolarHBondContact O-N 2.99Å; V153-Q155 PolarHBondContact O-N 3.47Å; Q155-A157 PolarHBondContact O-N 3.09Å; Q155-V158 PolarHBondContact O-N 2.93Å; Q155-D159 PolarHBondContact NE2-OD1 2.87Å; Q155-D159 WeakPolarHBondContact O-CB 3.46Å; Q155-D159 PolarHBondContact O-N 2.95Å; Q155-K191 PolarHBondContact NE2-O 2.89Å
156T98.8Very high98.5Very high29 Ų2928.6 Ų28.618%0.17815%0.149CC..Hα-helixtrans-64-41.5177.9-59.10000111.9L118 I121 K122 Q152 V153 V154 A160L118-T156 HydrophobicContact CB-CG2 4.38Å; L118-T156 WeakPolarHBondContact O-CG2 3.41Å; I121-T156 HydrophobicContact CB-CG2 4.26Å; I121-T156 HydrophobicContact CG2-CG2 4.02Å; K122-T156 HydrophobicContact CB-CG2 4.08Å; Q152-T156 WeakPolarHBondContact O-CB 3.36Å; Q152-T156 PolarHBondContact O-N 3.15Å; Q152-T156 PolarHBondContact O-OG1 2.89Å; V153-T156 PolarHBondContact O-N 3.06Å; V154-T156 VanDerWaalsContact C-N 3.28Å; V154-T156 PolarHBondContact O-N 3.12Å; T156-A160 WeakPolarHBondContact O-CB 3.49Å; T156-A160 PolarHBondContact O-N 3.48Å
157A98.8Very high98.6Very high0 Ų025.7 Ų25.70%014%0.136CC..Hα-helixtrans-66.4-42.3176.100000112.1I121 V125 F137 V153 V154 Q155 A160 G161 A162 I165I121-A157 HydrophobicContact CG2-CB 3.79Å; V125-A157 HydrophobicContact CG2-CB 4.46Å; F137-A157 HydrophobicContact CB-CB 3.9Å; F137-A157 HydrophobicContact CD1-CB 3.36Å; F137-A157 HydrophobicContact CD2-CB 4.29Å; F137-A157 HydrophobicContact CE1-CB 3.95Å; F137-A157 HydrophobicContact CG-CB 3.55Å; V153-A157 PolarHBondContact O-N 3.09Å; V154-A157 PolarHBondContact O-N 3.36Å; Q155-A157 PolarHBondContact O-N 3.09Å; A157-A160 PolarHBondContact O-N 3.08Å; A157-G161 PolarHBondContact O-N 2.92Å; A157-A162 HydrophobicContact CB-CB 4.2Å; A157-A162 VanDerWaalsContact O-CB 3.28Å; A157-A162 WeakPolarHBondContact O-CB 3.4Å; A157-A162 PolarHBondContact O-N 2.84Å; A157-I165 HydrophobicContact CB-CD1 4.09Å
158V98.7Very high98.6Very high1 Ų122.6 Ų22.61%0.00612%0.12CC..Hα-helixtrans-62.1-48.5174.8169.70000110.5V154 Q155 A160 G161 I165 T190 R194 I196V154-V158 HydrophobicContact CG1-CG2 4.38Å; V154-V158 WeakPolarHBondContact O-CG2 3.34Å; V154-V158 PolarHBondContact O-N 2.63Å; Q155-V158 PolarHBondContact O-N 2.93Å; V158-A160 PolarHBondContact O-N 2.91Å; V158-G161 PolarHBondContact O-N 2.91Å; V158-G161 VanDerWaalsContact O-N 3.08Å; V158-I165 HydrophobicContact CG2-CD1 3.87Å; V158-I165 HydrophobicContact CG2-CG1 3.94Å; V158-T190 HydrophobicContact CB-CG2 4.35Å; V158-T190 HydrophobicContact CG1-CG2 4.42Å; V158-T190 HydrophobicContact CG2-CG2 3.84Å; V158-R194 PolarHBondContact O-NH2 2.81Å; V158-I196 HydrophobicContact CG1-CD1 3.94Å; V158-I196 HydrophobicContact CG1-CG1 4.08Å; V158-I196 HydrophobicContact CG2-CD1 4.07Å; V158-I196 HydrophobicContact CG2-CG1 4.11Å; V158-I196 HydrophobicContact CG2-CG2 4.19Å
159D98.6Very high98.6Very high115 Ų11518.1 Ų18.162%0.61510%0.096SC*.Hα-helixtrans-61.5-31.2177.7-68-14.7000112.1Q155Q155-D159 PolarHBondContact NE2-OD1 2.87Å; Q155-D159 WeakPolarHBondContact O-CB 3.46Å; Q155-D159 PolarHBondContact O-N 2.95Å
160A98.5Very high98.5Very high11 Ų1119.2 Ų19.29%0.09110%0.103CC..Hα-helixtrans-79.6-10.3178.200000114.7V125 T126 T156 A157 V158V125-A160 HydrophobicContact CB-CB 3.8Å; V125-A160 HydrophobicContact CG1-CB 3.8Å; T126-A160 WeakPolarHBondContact CA-O 3.16Å; T156-A160 WeakPolarHBondContact O-CB 3.49Å; T156-A160 PolarHBondContact O-N 3.48Å; A157-A160 PolarHBondContact O-N 3.08Å; V158-A160 PolarHBondContact O-N 2.91Å
161G98.2Very high98.3Very high8 Ų820.8 Ų20.88%0.08211%0.113CC..THydrogen-bonded Turntrans1211.8174.200000116.3R129 A157 V158 R194R129-G161 WeakPolarHBondContact CD-O 3.4Å; A157-G161 PolarHBondContact O-N 2.92Å; V158-G161 PolarHBondContact O-N 2.91Å; V158-G161 VanDerWaalsContact O-N 3.08Å; G161-R194 VanDerWaalsContact C-NH2 3.26Å
162A98.5Very high98.2Very high0 Ų019.4 Ų19.40%011%0.106CC..  trans-58.4142.3174.300000110.7V125 F137 A157 I165 R194 I196V125-A162 HydrophobicContact CG1-CB 4.01Å; F137-A162 HydrophobicContact CB-CB 4.11Å; A157-A162 HydrophobicContact CB-CB 4.2Å; A157-A162 VanDerWaalsContact O-CB 3.28Å; A157-A162 WeakPolarHBondContact O-CB 3.4Å; A157-A162 PolarHBondContact O-N 2.84Å; A162-I165 HydrophobicContact CB-CD1 3.85Å; A162-R194 PolarHBondContact O-NH2 2.74Å; A162-I196 WeakPolarHBondContact O-CD1 3.27Å
163T98.1Very high97.9Very high20 Ų2018.7 Ų18.712%0.12310%0.101CC..SBendtrans-114.4-27.1177.152.40000111.6V135 I197V135-T163 PolarHBondContact N-OG1 3.5Å; V135-T163 PolarHBondContact O-N 2.85Å; V135-T163 PolarHBondContact O-OG1 2.88Å; T163-I197 PolarHBondContact O-N 3.02Å; T163-I197 VanDerWaalsContact O-N 3.14Å
164Y98.7Very high97.7Very high26 Ų2618.7 Ų18.710%0.10210%0.101CC..EExtended strand (participates in β ladder)trans-115.6138.9169.6-68-92.9000109.6E5 V134 V135 E136 F137 I197 R223E5-Y164 PolarHBondContact OE1-OH 3.04Å; E5-Y164 WeakPolarHBondContact OE2-CE1 3.38Å; E5-Y164 PolarHBondContact OE2-OH 3.2Å; E5-Y164 VanDerWaalsContact OE2-OH 3.04Å; V134-Y164 HydrophobicContact CG1-CD2 3.57Å; V134-Y164 HydrophobicContact CG1-CE2 3.47Å; V134-Y164 VanDerWaalsContact CG1-CE2 3.47Å; V135-Y164 PolarHBondContact O-N 3.11Å; V135-Y164 VanDerWaalsContact O-N 3.14Å; E136-Y164 WeakPolarHBondContact CA-O 3.09Å; E136-Y164 WeakPolarHBondContact OE2-CB 3.28Å; F137-Y164 PolarHBondContact N-O 3.33Å; Y164-I197 VanDerWaalsContact CA-O 3.31Å; Y164-I197 WeakPolarHBondContact CA-O 3.38Å; Y164-I197 HydrophobicContact CD1-CB 3.5Å; Y164-I197 VanDerWaalsContact CD1-CB 3.5Å; Y164-I197 HydrophobicContact CD1-CD1 4.42Å; Y164-I197 HydrophobicContact CD1-CG2 3.6Å; Y164-I197 HydrophobicContact CE1-CB 3.47Å; Y164-I197 VanDerWaalsContact CE1-CB 3.47Å; Y164-I197 HydrophobicContact CE1-CD1 3.52Å; Y164-I197 HydrophobicContact CE1-CG1 4.06Å; Y164-I197 HydrophobicContact CE1-CG2 3.52Å; Y164-I197 HydrophobicContact CG-CB 4.44Å; Y164-R223 VanDerWaalsContact CE1-NE 3.29Å; Y164-R223 PolarHBondContact OH-NH2 2.88Å
165I98.8Very high97.7Very high0 Ų021.8 Ų21.80%012%0.12CC..EExtended strand (participates in β ladder)trans-120.9110.1174.8-61.4-64.1000107.8F137 V154 A157 V158 A162 I167 I196 I197 F198 S199F137-I165 HydrophobicContact CB-CD1 4.26Å; F137-I165 HydrophobicContact CD1-CD1 4.49Å; V154-I165 HydrophobicContact CG1-CD1 4.38Å; V154-I165 HydrophobicContact CG1-CG1 4.2Å; V154-I165 HydrophobicContact CG1-CG2 3.95Å; V154-I165 HydrophobicContact CG2-CG2 3.9Å; A157-I165 HydrophobicContact CB-CD1 4.09Å; V158-I165 HydrophobicContact CG2-CD1 3.87Å; V158-I165 HydrophobicContact CG2-CG1 3.94Å; A162-I165 HydrophobicContact CB-CD1 3.85Å; I165-I167 HydrophobicContact CG2-CD1 3.72Å; I165-I167 HydrophobicContact CG2-CG1 4.29Å; I165-I196 HydrophobicContact CB-CG2 4.34Å; I165-I196 HydrophobicContact CG1-CG2 3.59Å; I165-I197 PolarHBondContact N-O 2.83Å; I165-F198 HydrophobicContact CB-CD1 3.95Å; I165-F198 HydrophobicContact CB-CE1 3.95Å; I165-F198 HydrophobicContact CB-CG 4.49Å; I165-F198 HydrophobicContact CB-CZ 4.49Å; I165-F198 HydrophobicContact CG2-CD1 3.88Å; I165-F198 HydrophobicContact CG2-CE1 3.73Å; I165-F198 CarbonylContact O-C 3.58Å; I165-F198 VanDerWaalsContact O-CA 3.27Å; I165-F198 WeakPolarHBondContact O-CA 3.4Å; I165-S199 PolarHBondContact O-N 3.48Å
166N98.8Very high97.7Very high1 Ų122.2 Ų22.21%0.00513%0.126CC..EExtended strand (participates in β ladder)trans-90.8135.5174.1177.126.8000109.8E136 F137 S138 P139 P168 S199 H201 E225E136-N166 HydrophobicContact CG-CB 4.23Å; F137-N166 PolarHBondContact O-N 3.37Å; S138-N166 VanDerWaalsContact OG-CB 3.26Å; S138-N166 WeakPolarHBondContact OG-CB 3.22Å; S138-N166 PolarHBondContact OG-ND2 3.01Å; P139-N166 WeakPolarHBondContact CD-O 3.26Å; N166-P168 WeakPolarHBondContact O-CD 2.97Å; N166-S199 CarbonylContact C-O 3.16Å; N166-S199 VanDerWaalsContact CA-O 3.27Å; N166-S199 WeakPolarHBondContact CA-O 3.15Å; N166-S199 PolarHBondContact OD1-O 3.01Å; N166-H201 WeakPolarHBondContact OD1-CB 3.49Å; N166-E225 VanDerWaalsContact CB-OE1 3.32Å; N166-E225 WeakPolarHBondContact CB-OE1 3.35Å; N166-E225 PolarHBondContact ND2-OE1 2.95Å; N166-E225 PolarHBondContact ND2-OE2 3.3Å; N166-E225 PolarHBondContact OD1-OE1 2.85Å
167I98.7Very high97.6Very high0 Ų028 Ų280%015%0.151CC..EExtended strand (participates in β ladder)trans-118.789.9179.6-56.7-60.9000107.8P139 A142 V154 I165 Y179 I182 F183 L186 F198 S199P139-I167 HydrophobicContact CG-CD1 4.06Å; A142-I167 HydrophobicContact CB-CG2 3.78Å; V154-I167 HydrophobicContact CG2-CD1 4.02Å; I165-I167 HydrophobicContact CG2-CD1 3.72Å; I165-I167 HydrophobicContact CG2-CG1 4.29Å; I167-Y179 HydrophobicContact CG2-CE2 4.33Å; I167-Y179 PolarHBondContact O-OH 3.47Å; I167-I182 HydrophobicContact CG2-CG2 3.97Å; I167-F183 HydrophobicContact CB-CE2 3.83Å; I167-F183 HydrophobicContact CB-CZ 3.7Å; I167-F183 HydrophobicContact CG1-CE2 4.44Å; I167-F183 HydrophobicContact CG1-CZ 4.11Å; I167-F183 HydrophobicContact CG2-CE2 4.06Å; I167-F183 HydrophobicContact CG2-CZ 4.45Å; I167-L186 HydrophobicContact CD1-CD1 3.47Å; I167-L186 VanDerWaalsContact CD1-CD1 3.47Å; I167-L186 HydrophobicContact CG1-CD1 3.8Å; I167-F198 HydrophobicContact CG1-CD1 4.35Å; I167-S199 PolarHBondContact N-O 2.89Å
168P98.4Very high97.6Very high6 Ų632.1 Ų32.14%0.03917%0.17CC..EExtended strand (participates in β ladder)trans-77.2134.8-174.929.7-35.8000112.8P139 A142 N166 T170 H201P139-P168 WeakPolarHBondContact O-CD 3.44Å; P139-P168 WeakPolarHBondContact O-CG 3.27Å; A142-P168 HydrophobicContact CB-CG 4.41Å; A142-P168 PolarHBondContact N-O 3.22Å; N166-P168 WeakPolarHBondContact O-CD 2.97Å; P168-T170 VanDerWaalsContact C-N 3.27Å; P168-T170 PolarHBondContact O-N 3.25Å; P168-H201 CarbonylContact C-O 3.56Å; P168-H201 WeakPolarHBondContact CA-O 3.21Å; P168-H201 HydrophobicContact CB-CB 4.15Å
169D98.2Very high97.6Very high0 Ų032.1 Ų32.10%017%0.17CC..EExtended strand (participates in β ladder)trans-88.671157.4-174.428.4000108.9T143 V171 G172 F173 T174 Y179 H201 H203T143-D169 HydrophobicContact CG2-CB 3.66Å; T143-D169 PolarHBondContact OG1-OD1 3.4Å; D169-V171 PolarHBondContact O-N 3.17Å; D169-G172 PolarHBondContact O-N 3.43Å; D169-G172 WeakPolarHBondContact OD2-CA 3.45Å; D169-F173 PolarHBondContact OD1-N 2.92Å; D169-F173 PolarHBondContact OD2-N 2.89Å; D169-F173 VanDerWaalsContact OD2-N 3.12Å; D169-T174 HydrophobicContact CB-CG2 4.18Å; D169-T174 WeakPolarHBondContact OD2-CG2 3.27Å; D169-T174 PolarHBondContact OD2-N 3.29Å; D169-Y179 HydrophobicContact CB-CE2 4.06Å; D169-H201 PolarHBondContact N-O 3.27Å; D169-H203 PolarHBondContact O-N 2.86Å
170T96.6Very high97.6Very high23 Ų2326.7 Ų26.714%0.14114%0.141CC..THydrogen-bonded Turntrans-54.6-30.1-168-59.70000113.8E140 D141 P168 H203 R234E140-T170 HydrophobicContact CG-CG2 4.44Å; D141-T170 WeakPolarHBondContact CA-OG1 3.29Å; D141-T170 PolarHBondContact N-OG1 3.26Å; P168-T170 VanDerWaalsContact C-N 3.27Å; P168-T170 PolarHBondContact O-N 3.25Å; T170-H203 PolarHBondContact O-CD2 3.18Å; T170-R234 PolarHBondContact O-NH2 3.03Å
171V95Very high97.6Very high35 Ų3530.1 Ų30.121%0.21216%0.158CC..THydrogen-bonded Turntrans-111.78.7-178.1-58.10000113.2D169 F173 D205D169-V171 PolarHBondContact O-N 3.17Å; V171-F173 VanDerWaalsContact C-N 3.28Å; V171-F173 HydrophobicContact CG2-CB 4.01Å; V171-F173 HydrophobicContact CG2-CD1 3.36Å; V171-F173 HydrophobicContact CG2-CE1 4.18Å; V171-F173 HydrophobicContact CG2-CG 3.92Å; V171-F173 PolarHBondContact O-N 2.82Å; V171-D205 WeakPolarHBondContact O-CB 3.4Å
172G95.9Very high97.6Very high0 Ų030.5 Ų30.50%016%0.158CC..SBendtrans60.928.3172.900000115.7D169 H203 L206D169-G172 PolarHBondContact O-N 3.43Å; D169-G172 WeakPolarHBondContact OD2-CA 3.45Å; G172-H203 WeakPolarHBondContact CA-O 3.28Å; G172-L206 WeakPolarHBondContact O-CB 3.28Å; G172-L206 WeakPolarHBondContact O-CG 3.37Å; G172-L206 PolarHBondContact O-N 3.37Å
173F92.8Very high97.6Very high82 Ų8230.5 Ų30.536%0.3616%0.158SC..  trans-107.6-11.8-167.593.5-66.1000115R144 D169 V171 L206R144-F173 HydrophobicContact CG-CD1 4.19Å; R144-F173 HydrophobicContact CG-CE1 3.22Å; R144-F173 HydrophobicContact CG-CE2 4.46Å; R144-F173 HydrophobicContact CG-CZ 3.4Å; R144-F173 VanDerWaalsContact CG-CZ 3.4Å; D169-F173 PolarHBondContact OD1-N 2.92Å; D169-F173 PolarHBondContact OD2-N 2.89Å; D169-F173 VanDerWaalsContact OD2-N 3.12Å; V171-F173 VanDerWaalsContact C-N 3.28Å; V171-F173 HydrophobicContact CG2-CB 4.01Å; V171-F173 HydrophobicContact CG2-CD1 3.36Å; V171-F173 HydrophobicContact CG2-CE1 4.18Å; V171-F173 HydrophobicContact CG2-CG 3.92Å; V171-F173 PolarHBondContact O-N 2.82Å; F173-L206 HydrophobicContact CB-CD1 4.19Å; F173-L206 WeakPolarHBondContact O-CD1 3.27Å
174T94.7Very high97.6Very high0 Ų033.9 Ų33.90%017%0.171CC..  trans-78.4166.9-177.1-164.80000111.7T143 D169 E178 Y179 M208 N212T143-T174 HydrophobicContact CG2-CG2 4.09Å; D169-T174 HydrophobicContact CB-CG2 4.18Å; D169-T174 WeakPolarHBondContact OD2-CG2 3.27Å; D169-T174 PolarHBondContact OD2-N 3.29Å; T174-E178 PolarHBondContact OG1-OE2 2.92Å; T174-Y179 HydrophobicContact CG2-CD2 3.73Å; T174-Y179 HydrophobicContact CG2-CG 3.89Å; T174-M208 WeakPolarHBondContact O-CE 3.42Å; T174-N212 VanDerWaalsContact CG2-ND2 3.31Å; T174-N212 WeakPolarHBondContact CG2-ND2 3.48Å; T174-N212 PolarHBondContact O-ND2 2.92Å
175T97.6Very high97.6Very high65 Ų6536.3 Ų36.340%0.39918%0.18SC..  trans-10415717763.70000111.9E177 E178 Y179 M208T175-E177 VanDerWaalsContact C-N 3.31Å; T175-E177 PolarHBondContact O-N 3.41Å; T175-E178 PolarHBondContact O-N 2.88Å; T175-E178 VanDerWaalsContact O-N 3.17Å; T175-E178 WeakPolarHBondContact OG1-CB 3.35Å; T175-Y179 WeakPolarHBondContact O-CB 3.18Å; T175-Y179 PolarHBondContact O-N 3.13Å; T175-M208 HydrophobicContact CG2-CE 4.34Å
176P98.3Very high97.6Very high44 Ų4436.3 Ų36.329%0.28618%0.18SC..Hα-helixtrans-59-38.8-174.4-28.535.1000114.2G180 A211 N212 A215P176-G180 PolarHBondContact O-N 2.85Å; P176-A211 HydrophobicContact CB-CB 4.49Å; P176-A211 HydrophobicContact CG-CB 3.69Å; P176-N212 VanDerWaalsContact CA-OD1 3.22Å; P176-N212 WeakPolarHBondContact CA-OD1 3.23Å; P176-N212 WeakPolarHBondContact CD-OD1 3.46Å; P176-N212 WeakPolarHBondContact CG-OD1 3.38Å; P176-A215 HydrophobicContact CB-CB 3.97Å; P176-A215 WeakPolarHBondContact O-CB 3.46Å
177E98.1Very high97.6Very high151 Ų15139.1 Ų39.171%0.70620%0.195SC*.Hα-helixtrans-68-45.4178.1-176.8174.4-174.700111.6T175 N181T175-E177 VanDerWaalsContact C-N 3.31Å; T175-E177 PolarHBondContact O-N 3.41Å; E177-N181 WeakPolarHBondContact O-CB 3.43Å; E177-N181 PolarHBondContact O-N 3.04Å; E177-N181 PolarHBondContact O-ND2 2.93Å; E177-N181 VanDerWaalsContact O-ND2 3.11Å
178E97.8Very high97.5Very high87 Ų8745.3 Ų45.341%0.40722%0.224SC..Hα-helixtrans-60.7-48.3177.5-177.1179.3-154.500111.2T174 T175 N181 I182T174-E178 PolarHBondContact OG1-OE2 2.92Å; T175-E178 PolarHBondContact O-N 2.88Å; T175-E178 VanDerWaalsContact O-N 3.17Å; T175-E178 WeakPolarHBondContact OG1-CB 3.35Å; E178-N181 WeakPolarHBondContact O-CB 3.46Å; E178-N181 PolarHBondContact O-N 2.8Å; E178-I182 WeakPolarHBondContact O-CG1 3.45Å; E178-I182 PolarHBondContact O-N 3.46Å
179Y98.5Very high97.5Very high0 Ų048.3 Ų48.30%024%0.239CC..Hα-helixtrans-66.7-42.6-179.5-163.7-118.2000112.6T143 I167 D169 T174 T175 N181 I182 F183 P200 H201 C202 N212 A216T143-Y179 HydrophobicContact CG2-CD2 3.63Å; T143-Y179 HydrophobicContact CG2-CE2 3.63Å; I167-Y179 HydrophobicContact CG2-CE2 4.33Å; I167-Y179 PolarHBondContact O-OH 3.47Å; D169-Y179 HydrophobicContact CB-CE2 4.06Å; T174-Y179 HydrophobicContact CG2-CD2 3.73Å; T174-Y179 HydrophobicContact CG2-CG 3.89Å; T175-Y179 WeakPolarHBondContact O-CB 3.18Å; T175-Y179 PolarHBondContact O-N 3.13Å; Y179-N181 VanDerWaalsContact C-N 3.27Å; Y179-N181 PolarHBondContact O-N 2.95Å; Y179-I182 WeakPolarHBondContact O-CB 3.49Å; Y179-I182 PolarHBondContact O-N 3.01Å; Y179-I182 VanDerWaalsContact O-N 3.16Å; Y179-F183 HydrophobicContact CD1-CD2 4.27Å; Y179-F183 HydrophobicContact CD1-CE2 4.12Å; Y179-F183 HydrophobicContact CD2-CE2 4.44Å; Y179-F183 HydrophobicContact CE1-CD2 4.15Å; Y179-F183 AromaticContact CE1-CE2 3.56Å; Y179-F183 HydrophobicContact CE1-CE2 3.56Å; Y179-F183 HydrophobicContact CE1-CZ 4.4Å; Y179-F183 AromaticContact CE2-CE2 3.89Å; Y179-F183 HydrophobicContact CE2-CE2 3.89Å; Y179-F183 AromaticContact CZ-CE2 3.44Å; Y179-F183 VanDerWaalsContact CZ-CE2 3.44Å; Y179-F183 WeakPolarHBondContact O-CD2 3.42Å; Y179-F183 PolarHBondContact O-N 2.85Å; Y179-F183 VanDerWaalsContact O-N 3.13Å; Y179-P200 HydrophobicContact CE1-CB 3.73Å; Y179-P200 VanDerWaalsContact OH-CA 3.31Å; Y179-P200 WeakPolarHBondContact OH-CA 3.35Å; Y179-P200 WeakPolarHBondContact OH-CB 3.5Å; Y179-H201 PolarHBondContact OH-N 3.11Å; Y179-C202 WeakPolarHBondContact CE1-SG 3.34Å; Y179-C202 PolarHBondContact OH-SG 2.88Å; Y179-N212 HydrophobicContact CD1-CB 3.8Å; Y179-N212 VanDerWaalsContact CD1-O 3.28Å; Y179-N212 WeakPolarHBondContact CD1-O 3.37Å; Y179-N212 HydrophobicContact CE1-CB 4.28Å; Y179-N212 HydrophobicContact CG-CB 4.28Å; Y179-A216 HydrophobicContact CD1-CB 3.93Å; Y179-A216 HydrophobicContact CE1-CB 3.76Å
180G98.5Very high97.5Very high1 Ų149.2 Ų49.21%0.0125%0.245CC..Hα-helixtrans-57.8-40.2172.200000112.5P176 F183 K184 N219P176-G180 PolarHBondContact O-N 2.85Å; G180-F183 PolarHBondContact O-N 2.71Å; G180-K184 WeakPolarHBondContact O-CB 3.47Å; G180-K184 PolarHBondContact O-N 2.87Å; G180-N219 VanDerWaalsContact CA-ND2 3.32Å; G180-N219 WeakPolarHBondContact CA-ND2 3.34Å; G180-N219 VanDerWaalsContact O-CB 3.23Å; G180-N219 WeakPolarHBondContact O-CB 3.42Å
181N98.4Very high97.6Very high84 Ų8455.9 Ų55.945%0.44927%0.272SS..Hα-helixtrans-66.2-37176.2-72.8-27.9000112.6E177 E178 Y179 K184 Y185E177-N181 WeakPolarHBondContact O-CB 3.43Å; E177-N181 PolarHBondContact O-N 3.04Å; E177-N181 PolarHBondContact O-ND2 2.93Å; E177-N181 VanDerWaalsContact O-ND2 3.11Å; E178-N181 WeakPolarHBondContact O-CB 3.46Å; E178-N181 PolarHBondContact O-N 2.8Å; Y179-N181 VanDerWaalsContact C-N 3.27Å; Y179-N181 PolarHBondContact O-N 2.95Å; N181-K184 PolarHBondContact O-N 3.48Å; N181-Y185 VanDerWaalsContact O-CB 3.23Å; N181-Y185 WeakPolarHBondContact O-CB 3.19Å; N181-Y185 PolarHBondContact O-N 2.93Å
182I98.6Very high97.7Very high15 Ų1556.7 Ų56.78%0.07728%0.279CS..Hα-helixtrans-59.3-50.7173.3-67.3168.1000110T143 L147 L150 I167 E178 Y179 K184 Y185 L186T143-I182 HydrophobicContact CG2-CD1 4.35Å; L147-I182 HydrophobicContact CD1-CG1 4.34Å; L147-I182 HydrophobicContact CD1-CG2 4.5Å; L150-I182 HydrophobicContact CD2-CG2 3.96Å; I167-I182 HydrophobicContact CG2-CG2 3.97Å; E178-I182 WeakPolarHBondContact O-CG1 3.45Å; E178-I182 PolarHBondContact O-N 3.46Å; Y179-I182 WeakPolarHBondContact O-CB 3.49Å; Y179-I182 PolarHBondContact O-N 3.01Å; Y179-I182 VanDerWaalsContact O-N 3.16Å; I182-K184 PolarHBondContact O-N 2.9Å; I182-Y185 PolarHBondContact O-N 3.4Å; I182-L186 HydrophobicContact CG2-CD1 3.77Å; I182-L186 HydrophobicContact CG2-CG 4.34Å; I182-L186 VanDerWaalsContact O-CG 3.3Å; I182-L186 WeakPolarHBondContact O-CG 3.48Å; I182-L186 PolarHBondContact O-N 3.34Å
183F98.6Very high97.7Very high0 Ų063.6 Ų63.60%032%0.316CS..Hα-helixtrans-58.7-49.4178.5-89.8-96.7000112.1I167 Y179 G180 Y185 L186 I187 F198 S199 P200 A216 N219 A221I167-F183 HydrophobicContact CB-CE2 3.83Å; I167-F183 HydrophobicContact CB-CZ 3.7Å; I167-F183 HydrophobicContact CG1-CE2 4.44Å; I167-F183 HydrophobicContact CG1-CZ 4.11Å; I167-F183 HydrophobicContact CG2-CE2 4.06Å; I167-F183 HydrophobicContact CG2-CZ 4.45Å; Y179-F183 HydrophobicContact CD1-CD2 4.27Å; Y179-F183 HydrophobicContact CD1-CE2 4.12Å; Y179-F183 HydrophobicContact CD2-CE2 4.44Å; Y179-F183 HydrophobicContact CE1-CD2 4.15Å; Y179-F183 AromaticContact CE1-CE2 3.56Å; Y179-F183 HydrophobicContact CE1-CE2 3.56Å; Y179-F183 HydrophobicContact CE1-CZ 4.4Å; Y179-F183 AromaticContact CE2-CE2 3.89Å; Y179-F183 HydrophobicContact CE2-CE2 3.89Å; Y179-F183 AromaticContact CZ-CE2 3.44Å; Y179-F183 VanDerWaalsContact CZ-CE2 3.44Å; Y179-F183 WeakPolarHBondContact O-CD2 3.42Å; Y179-F183 PolarHBondContact O-N 2.85Å; Y179-F183 VanDerWaalsContact O-N 3.13Å; G180-F183 PolarHBondContact O-N 2.71Å; F183-Y185 VanDerWaalsContact C-N 3.34Å; F183-Y185 PolarHBondContact O-N 2.68Å; F183-L186 PolarHBondContact O-N 2.89Å; F183-I187 HydrophobicContact CD1-CD1 4.48Å; F183-I187 WeakPolarHBondContact O-CB 3.29Å; F183-I187 WeakPolarHBondContact O-CD1 3.26Å; F183-I187 VanDerWaalsContact O-CG1 3.24Å; F183-I187 WeakPolarHBondContact O-CG1 3.49Å; F183-I187 PolarHBondContact O-N 3.03Å; F183-F198 HydrophobicContact CD1-CB 4.02Å; F183-F198 HydrophobicContact CE1-CB 3.87Å; F183-S199 WeakPolarHBondContact CZ-O 3.19Å; F183-P200 HydrophobicContact CE1-CB 4.45Å; F183-P200 HydrophobicContact CE2-CB 4.15Å; F183-P200 HydrophobicContact CZ-CB 3.71Å; F183-P200 HydrophobicContact CZ-CG 4.32Å; F183-A216 HydrophobicContact CB-CB 4.48Å; F183-A216 HydrophobicContact CD1-CB 3.97Å; F183-A216 HydrophobicContact CD2-CB 3.47Å; F183-A216 VanDerWaalsContact CD2-CB 3.47Å; F183-A216 HydrophobicContact CE1-CB 4.05Å; F183-A216 HydrophobicContact CE2-CB 3.6Å; F183-A216 HydrophobicContact CG-CB 3.68Å; F183-A216 HydrophobicContact CZ-CB 3.89Å; F183-N219 HydrophobicContact CB-CB 4.19Å; F183-A221 HydrophobicContact CD1-CB 3.61Å; F183-A221 HydrophobicContact CE1-CB 3.57Å
184K98.5Very high97.9Very high92 Ų9263.8 Ų63.840%0.431%0.314SS..Hα-helixtrans-56.4-49.4177.8-176.3177.1176.8-177.80111.4G180 N181 I182 L186 I187 E188 N219G180-K184 WeakPolarHBondContact O-CB 3.47Å; G180-K184 PolarHBondContact O-N 2.87Å; N181-K184 PolarHBondContact O-N 3.48Å; I182-K184 PolarHBondContact O-N 2.9Å; K184-L186 PolarHBondContact O-N 3.4Å; K184-I187 PolarHBondContact O-N 3.12Å; K184-E188 WeakPolarHBondContact CE-OE1 3.34Å; K184-E188 HydrophobicContact CG-CG 4.41Å; K184-E188 WeakPolarHBondContact O-CB 3.38Å; K184-E188 VanDerWaalsContact O-CG 3.3Å; K184-E188 WeakPolarHBondContact O-CG 3.09Å; K184-E188 PolarHBondContact O-N 2.72Å; K184-N219 HydrophobicContact CB-CB 4.1Å
185Y98.7Very high97.9Very high76 Ų7671.5 Ų71.530%0.29835%0.351SS..Hα-helixtrans-60.7-47-179-179.9-97.2000111.8L147 L151 N181 I182 F183 E188 N189L147-Y185 HydrophobicContact CD1-CD1 3.53Å; L147-Y185 HydrophobicContact CD1-CE1 4.04Å; L147-Y185 HydrophobicContact CD1-CG 4.2Å; L147-Y185 HydrophobicContact CD2-CD1 3.83Å; L147-Y185 HydrophobicContact CD2-CD2 4.24Å; L147-Y185 HydrophobicContact CD2-CE1 4.07Å; L147-Y185 HydrophobicContact CD2-CE2 4.48Å; L147-Y185 HydrophobicContact CD2-CG 3.9Å; L147-Y185 HydrophobicContact CG-CD1 3.56Å; L147-Y185 HydrophobicContact CG-CE1 3.62Å; L147-Y185 HydrophobicContact CG-CG 4.17Å; L151-Y185 HydrophobicContact CB-CE1 4.05Å; L151-Y185 HydrophobicContact CD2-CE1 3.95Å; L151-Y185 HydrophobicContact CG-CE1 4.49Å; N181-Y185 VanDerWaalsContact O-CB 3.23Å; N181-Y185 WeakPolarHBondContact O-CB 3.19Å; N181-Y185 PolarHBondContact O-N 2.93Å; I182-Y185 PolarHBondContact O-N 3.4Å; F183-Y185 VanDerWaalsContact C-N 3.34Å; F183-Y185 PolarHBondContact O-N 2.68Å; Y185-E188 PolarHBondContact O-N 2.91Å; Y185-N189 WeakPolarHBondContact O-CB 3.46Å; Y185-N189 PolarHBondContact O-N 3.33Å; Y185-N189 VanDerWaalsContact O-N 3.09Å; Y185-N189 PolarHBondContact O-ND2 2.76Å
186L98.7Very high97.9Very high0 Ų069.7 Ų69.70%034%0.338CS..Hα-helixtrans-66.6-42.9-178.8-66.6174.2000112.1L150 L151 V154 I167 I182 F183 K184 N189 T190 F198L150-L186 HydrophobicContact CD2-CD1 4Å; L150-L186 HydrophobicContact CD2-CD2 4.49Å; L150-L186 HydrophobicContact CG-CD1 4.26Å; L150-L186 HydrophobicContact CG-CD2 4.18Å; L151-L186 HydrophobicContact CB-CD2 4.17Å; L151-L186 HydrophobicContact CD1-CD2 4.28Å; V154-L186 HydrophobicContact CG2-CD1 4.33Å; V154-L186 HydrophobicContact CG2-CD2 4.21Å; I167-L186 HydrophobicContact CD1-CD1 3.47Å; I167-L186 VanDerWaalsContact CD1-CD1 3.47Å; I167-L186 HydrophobicContact CG1-CD1 3.8Å; I182-L186 HydrophobicContact CG2-CD1 3.77Å; I182-L186 HydrophobicContact CG2-CG 4.34Å; I182-L186 VanDerWaalsContact O-CG 3.3Å; I182-L186 WeakPolarHBondContact O-CG 3.48Å; I182-L186 PolarHBondContact O-N 3.34Å; F183-L186 PolarHBondContact O-N 2.89Å; K184-L186 PolarHBondContact O-N 3.4Å; L186-N189 PolarHBondContact O-N 2.92Å; L186-T190 WeakPolarHBondContact O-CB 3.46Å; L186-T190 PolarHBondContact O-N 3.5Å; L186-T190 PolarHBondContact O-OG1 3.25Å; L186-F198 HydrophobicContact CB-CD1 4.47Å; L186-F198 HydrophobicContact CB-CE1 3.73Å; L186-F198 HydrophobicContact CB-CZ 4.24Å; L186-F198 HydrophobicContact CD1-CE1 4.47Å
187I98.2Very high98Very high61 Ų6169 Ų6931%0.31333%0.332SS..Hα-helixtrans-63-42.2177.4-70.1165.3000111.2F183 K184 F198 N219F183-I187 HydrophobicContact CD1-CD1 4.48Å; F183-I187 WeakPolarHBondContact O-CB 3.29Å; F183-I187 WeakPolarHBondContact O-CD1 3.26Å; F183-I187 VanDerWaalsContact O-CG1 3.24Å; F183-I187 WeakPolarHBondContact O-CG1 3.49Å; F183-I187 PolarHBondContact O-N 3.03Å; K184-I187 PolarHBondContact O-N 3.12Å; I187-F198 HydrophobicContact CB-CE2 4.49Å; I187-F198 HydrophobicContact CD1-CB 4.28Å; I187-F198 HydrophobicContact CD1-CD2 4.24Å; I187-F198 HydrophobicContact CD1-CG 4.28Å; I187-F198 HydrophobicContact CG1-CB 4.31Å; I187-F198 HydrophobicContact CG1-CD1 4.31Å; I187-F198 HydrophobicContact CG1-CD2 3.45Å; I187-F198 VanDerWaalsContact CG1-CD2 3.45Å; I187-F198 HydrophobicContact CG1-CE2 3.72Å; I187-F198 HydrophobicContact CG1-CG 3.77Å; I187-F198 HydrophobicContact CG1-CZ 4.26Å; I187-N219 WeakPolarHBondContact CD1-O 3.11Å
188E98.1Very high98Very high130 Ų13062.3 Ų62.361%0.60730%0.3SS*.Hα-helixtrans-72.5-27.1-179.1-73.5176.4172.200113.5K184 Y185K184-E188 WeakPolarHBondContact CE-OE1 3.34Å; K184-E188 HydrophobicContact CG-CG 4.41Å; K184-E188 WeakPolarHBondContact O-CB 3.38Å; K184-E188 VanDerWaalsContact O-CG 3.3Å; K184-E188 WeakPolarHBondContact O-CG 3.09Å; K184-E188 PolarHBondContact O-N 2.72Å; Y185-E188 PolarHBondContact O-N 2.91Å
189N98.5Very high98Very high68 Ų6858.1 Ų58.136%0.36428%0.281SS..Hα-helixtrans-110-16.4-170.4-68.8-87.1000114.6L151 Y185 L186 K191L151-N189 HydrophobicContact CD1-CB 3.86Å; L151-N189 HydrophobicContact CD2-CB 3.74Å; L151-N189 HydrophobicContact CG-CB 4.48Å; Y185-N189 WeakPolarHBondContact O-CB 3.46Å; Y185-N189 PolarHBondContact O-N 3.33Å; Y185-N189 VanDerWaalsContact O-N 3.09Å; Y185-N189 PolarHBondContact O-ND2 2.76Å; L186-N189 PolarHBondContact O-N 2.92Å; N189-K191 PolarHBondContact O-N 3.38Å
190T98.4Very high98Very high19 Ų1958.1 Ų58.112%0.11728%0.281CS..  trans-75.6124.1176.4-61.70000109.6V154 V158 L186 F198V154-T190 HydrophobicContact CG1-CG2 4.04Å; V154-T190 WeakPolarHBondContact CG1-OG1 3.5Å; V158-T190 HydrophobicContact CB-CG2 4.35Å; V158-T190 HydrophobicContact CG1-CG2 4.42Å; V158-T190 HydrophobicContact CG2-CG2 3.84Å; L186-T190 WeakPolarHBondContact O-CB 3.46Å; L186-T190 PolarHBondContact O-N 3.5Å; L186-T190 PolarHBondContact O-OG1 3.25Å; T190-F198 HydrophobicContact CG2-CZ 4.44Å
191K98.1Very high98Very high164 Ų16458.4 Ų58.471%0.71328%0.282SS*.  trans-95.4133.4178.8-63178.7-176.6174.50109.3Q155 N189Q155-K191 PolarHBondContact NE2-O 2.89Å; N189-K191 PolarHBondContact O-N 3.38Å
192S97.5Very high98Very high52 Ų5254.4 Ų54.436%0.36426%0.261SS..  trans-148148.9179.7-177.30000110.4R194 I196S192-R194 VanDerWaalsContact C-N 3.3Å; S192-R194 VanDerWaalsContact CB-O 3.26Å; S192-R194 WeakPolarHBondContact CB-O 3.42Å; S192-R194 WeakPolarHBondContact OG-CG 3.4Å; S192-R194 PolarHBondContact OG-N 2.74Å; S192-R194 VanDerWaalsContact OG-N 3.13Å; S192-R194 PolarHBondContact OG-O 2.84Å; S192-I196 WeakPolarHBondContact OG-CG1 3.4Å
193D95.4Very high98Very high145 Ų14554.2 Ų54.278%0.77526%0.259SS*.SBendtrans-87.1-3.6170.963.7-8.9000112.9
194R95.8Very high98Very high85 Ų8556.6 Ų56.632%0.32127%0.272SS..SBendtrans-139.6166.9-178.863.1-170.7176.9-84-1.9111.5V158 G161 A162 S192 I196V158-R194 PolarHBondContact O-NH2 2.81Å; G161-R194 VanDerWaalsContact C-NH2 3.26Å; A162-R194 PolarHBondContact O-NH2 2.74Å; S192-R194 VanDerWaalsContact C-N 3.3Å; S192-R194 VanDerWaalsContact CB-O 3.26Å; S192-R194 WeakPolarHBondContact CB-O 3.42Å; S192-R194 WeakPolarHBondContact OG-CG 3.4Å; S192-R194 PolarHBondContact OG-N 2.74Å; S192-R194 VanDerWaalsContact OG-N 3.13Å; S192-R194 PolarHBondContact OG-O 2.84Å; R194-I196 HydrophobicContact CG-CD1 4.07Å; R194-I196 PolarHBondContact O-N 3.26Å
195E96.2Very high97.9Very high163 Ų16355 Ų5576%0.76227%0.268SS*.  trans-64.5134172.5-174.6171.5-14700110.5I197E195-I197 HydrophobicContact CG-CG1 4.47Å
196I98.2Very high97.9Very high26 Ų2656.4 Ų56.413%0.13328%0.28CS..  trans-120.8123.8174.7-57.7-61.1000107.7V158 A162 I165 S192 R194 F198V158-I196 HydrophobicContact CG1-CD1 3.94Å; V158-I196 HydrophobicContact CG1-CG1 4.08Å; V158-I196 HydrophobicContact CG2-CD1 4.07Å; V158-I196 HydrophobicContact CG2-CG1 4.11Å; V158-I196 HydrophobicContact CG2-CG2 4.19Å; A162-I196 WeakPolarHBondContact O-CD1 3.27Å; I165-I196 HydrophobicContact CB-CG2 4.34Å; I165-I196 HydrophobicContact CG1-CG2 3.59Å; S192-I196 WeakPolarHBondContact OG-CG1 3.4Å; R194-I196 HydrophobicContact CG-CD1 4.07Å; R194-I196 PolarHBondContact O-N 3.26Å; I196-F198 HydrophobicContact CB-CE2 4.32Å; I196-F198 HydrophobicContact CG2-CD2 4.2Å; I196-F198 HydrophobicContact CG2-CE2 3.81Å; I196-F198 HydrophobicContact CG2-CZ 4.32Å
197I98.4Very high97.8Very high31 Ų3159.1 Ų59.116%0.15931%0.308CS..EExtended strand (participates in β ladder)trans-98.5120.7179.4-65.5169.4000109.1T163 Y164 I165 E195 R223T163-I197 PolarHBondContact O-N 3.02Å; T163-I197 VanDerWaalsContact O-N 3.14Å; Y164-I197 VanDerWaalsContact CA-O 3.31Å; Y164-I197 WeakPolarHBondContact CA-O 3.38Å; Y164-I197 HydrophobicContact CD1-CB 3.5Å; Y164-I197 VanDerWaalsContact CD1-CB 3.5Å; Y164-I197 HydrophobicContact CD1-CD1 4.42Å; Y164-I197 HydrophobicContact CD1-CG2 3.6Å; Y164-I197 HydrophobicContact CE1-CB 3.47Å; Y164-I197 VanDerWaalsContact CE1-CB 3.47Å; Y164-I197 HydrophobicContact CE1-CD1 3.52Å; Y164-I197 HydrophobicContact CE1-CG1 4.06Å; Y164-I197 HydrophobicContact CE1-CG2 3.52Å; Y164-I197 HydrophobicContact CG-CB 4.44Å; I165-I197 PolarHBondContact N-O 2.83Å; E195-I197 HydrophobicContact CG-CG1 4.47Å; I197-R223 HydrophobicContact CG2-CB 3.91Å
198F98.7Very high97.7Very high9 Ų958.4 Ų58.44%0.03930%0.304CS..EExtended strand (participates in β ladder)trans-88.5139.8176.3-73.7-100.3000111.3V154 I165 I167 F183 L186 I187 T190 I196 A221 G222 R223V154-F198 HydrophobicContact CG1-CE1 4.13Å; V154-F198 HydrophobicContact CG1-CZ 4.22Å; I165-F198 HydrophobicContact CB-CD1 3.95Å; I165-F198 HydrophobicContact CB-CE1 3.95Å; I165-F198 HydrophobicContact CB-CG 4.49Å; I165-F198 HydrophobicContact CB-CZ 4.49Å; I165-F198 HydrophobicContact CG2-CD1 3.88Å; I165-F198 HydrophobicContact CG2-CE1 3.73Å; I165-F198 CarbonylContact O-C 3.58Å; I165-F198 VanDerWaalsContact O-CA 3.27Å; I165-F198 WeakPolarHBondContact O-CA 3.4Å; I167-F198 HydrophobicContact CG1-CD1 4.35Å; F183-F198 HydrophobicContact CD1-CB 4.02Å; F183-F198 HydrophobicContact CE1-CB 3.87Å; L186-F198 HydrophobicContact CB-CD1 4.47Å; L186-F198 HydrophobicContact CB-CE1 3.73Å; L186-F198 HydrophobicContact CB-CZ 4.24Å; L186-F198 HydrophobicContact CD1-CE1 4.47Å; I187-F198 HydrophobicContact CB-CE2 4.49Å; I187-F198 HydrophobicContact CD1-CB 4.28Å; I187-F198 HydrophobicContact CD1-CD2 4.24Å; I187-F198 HydrophobicContact CD1-CG 4.28Å; I187-F198 HydrophobicContact CG1-CB 4.31Å; I187-F198 HydrophobicContact CG1-CD1 4.31Å; I187-F198 HydrophobicContact CG1-CD2 3.45Å; I187-F198 VanDerWaalsContact CG1-CD2 3.45Å; I187-F198 HydrophobicContact CG1-CE2 3.72Å; I187-F198 HydrophobicContact CG1-CG 3.77Å; I187-F198 HydrophobicContact CG1-CZ 4.26Å; T190-F198 HydrophobicContact CG2-CZ 4.44Å; I196-F198 HydrophobicContact CB-CE2 4.32Å; I196-F198 HydrophobicContact CG2-CD2 4.2Å; I196-F198 HydrophobicContact CG2-CE2 3.81Å; I196-F198 HydrophobicContact CG2-CZ 4.32Å; F198-A221 CarbonylContact O-C 3.5Å; F198-A221 WeakPolarHBondContact O-CA 3.16Å; F198-G222 PolarHBondContact O-N 3.44Å; F198-R223 PolarHBondContact O-N 3.14Å; F198-R223 VanDerWaalsContact O-N 3.14Å
199S98.7Very high97.7Very high0 Ų052.3 Ų52.30%028%0.276CS..EExtended strand (participates in β ladder)trans-127.3121.8-175.4-170.60000110.5I165 N166 I167 F183 R223 E225I165-S199 PolarHBondContact O-N 3.48Å; N166-S199 CarbonylContact C-O 3.16Å; N166-S199 VanDerWaalsContact CA-O 3.27Å; N166-S199 WeakPolarHBondContact CA-O 3.15Å; N166-S199 PolarHBondContact OD1-O 3.01Å; I167-S199 PolarHBondContact N-O 2.89Å; F183-S199 WeakPolarHBondContact CZ-O 3.19Å; S199-R223 WeakPolarHBondContact OG-CG 3.41Å; S199-E225 WeakPolarHBondContact CB-OE1 3.44Å; S199-E225 WeakPolarHBondContact OG-CG 3.23Å; S199-E225 PolarHBondContact OG-OE1 3.15Å
200P98.6Very high97.7Very high0 Ų050.5 Ų50.50%027%0.267CS..EExtended strand (participates in β ladder)trans-76.7140.716327.6-39.5000112Y179 F183 T213 A216 A221 R223 V224 E225Y179-P200 HydrophobicContact CE1-CB 3.73Å; Y179-P200 VanDerWaalsContact OH-CA 3.31Å; Y179-P200 WeakPolarHBondContact OH-CA 3.35Å; Y179-P200 WeakPolarHBondContact OH-CB 3.5Å; F183-P200 HydrophobicContact CE1-CB 4.45Å; F183-P200 HydrophobicContact CE2-CB 4.15Å; F183-P200 HydrophobicContact CZ-CB 3.71Å; F183-P200 HydrophobicContact CZ-CG 4.32Å; P200-T213 HydrophobicContact CB-CG2 4.49Å; P200-T213 HydrophobicContact CG-CG2 3.99Å; P200-A216 HydrophobicContact CB-CB 3.76Å; P200-A216 HydrophobicContact CG-CB 3.86Å; P200-A221 VanDerWaalsContact CD-CB 3.46Å; P200-A221 HydrophobicContact CG-CB 4.23Å; P200-R223 WeakPolarHBondContact CD-O 3.2Å; P200-V224 HydrophobicContact CG-CB 4.49Å; P200-V224 HydrophobicContact CG-CG2 4.49Å; P200-E225 PolarHBondContact O-N 3.15Å
201H98.7Very high97.7Very high7 Ų751.8 Ų51.83%0.03228%0.279CS..EExtended strand (participates in β ladder)trans-134.193.7171.4-176.5113.2000107.8D13 N166 P168 D169 Y179 H203 E225 N237D13-H201 IonicContact OD2-CE1 3.61Å; D13-H201 IonicContact OD2-NE2 3.23Å; D13-H201 PolarHBondContact OD2-NE2 2.93Å; N166-H201 WeakPolarHBondContact OD1-CB 3.49Å; P168-H201 CarbonylContact C-O 3.56Å; P168-H201 WeakPolarHBondContact CA-O 3.21Å; P168-H201 HydrophobicContact CB-CB 4.15Å; D169-H201 PolarHBondContact N-O 3.27Å; Y179-H201 PolarHBondContact OH-N 3.11Å; H201-H203 AromaticContact CD2-NE2 3.97Å; H201-H203 AromaticContact NE2-NE2 3.66Å; H201-E225 HydrophobicContact CB-CB 3.94Å; H201-E225 IonicContact CE1-OE2 2.76Å; H201-E225 IonicContact CG-OE2 2.78Å; H201-E225 WeakPolarHBondContact ND1-CB 3.48Å; H201-E225 IonicContact ND1-OE2 3.61Å; H201-E225 PolarHBondContact ND1-OE2 2.96Å; H201-N237 PolarHBondContact NE2-OD1 2.93Å
202C98.6Very high97.8Very high0 Ų044 Ų440%025%0.245CC..EExtended strand (participates in β ladder)trans-103.5128.2-174-60.10000111.4Y179 A209 N212 T213 N237 V238Y179-C202 WeakPolarHBondContact CE1-SG 3.34Å; Y179-C202 PolarHBondContact OH-SG 2.88Å; C202-A209 HydrophobicContact CB-CB 3.88Å; C202-N212 HydrophobicContact CB-CB 4.5Å; C202-T213 PolarHBondContact SG-OG1 3.35Å; C202-N237 CarbonylContact O-C 3.56Å; C202-V238 PolarHBondContact O-N 3.45Å
203H98.4Very high97.8Very high10 Ų1041.5 Ų41.55%0.04623%0.228CC..BIsolated β-bridgetrans-83.8164.1161.9-71.7-94.4000111.2D13 D169 T170 G172 H201 A209 G236 N237D13-H203 IonicContact OD1-CE1 3.49Å; D169-H203 PolarHBondContact O-N 2.86Å; T170-H203 PolarHBondContact O-CD2 3.18Å; G172-H203 WeakPolarHBondContact CA-O 3.28Å; H201-H203 AromaticContact CD2-NE2 3.97Å; H201-H203 AromaticContact NE2-NE2 3.66Å; H203-A209 WeakPolarHBondContact O-CB 3.29Å; H203-G236 VanDerWaalsContact CA-O 3.29Å; H203-G236 WeakPolarHBondContact CA-O 3.35Å; H203-G236 PolarHBondContact ND1-O 2.91Å; H203-N237 PolarHBondContact CE1-OD1 2.82Å
204D97.9Very high98Very high50 Ų5035.4 Ų35.427%0.26720%0.195SC..  trans-111.723.8-167.9-153.940.3000115.5L206 G207 M208 A209 A235 G236D204-L206 PolarHBondContact O-N 3.18Å; D204-G207 PolarHBondContact O-N 2.88Å; D204-G207 WeakPolarHBondContact OD1-CA 3.49Å; D204-M208 PolarHBondContact OD1-N 2.81Å; D204-A209 HydrophobicContact CB-CB 3.76Å; D204-A209 WeakPolarHBondContact OD1-CB 3.49Å; D204-A209 PolarHBondContact OD1-N 2.9Å; D204-A235 HydrophobicContact CB-CB 4.26Å; D204-A235 WeakPolarHBondContact O-CB 3.12Å; D204-G236 PolarHBondContact N-O 3.42Å
205D97.1Very high98.1Very high60 Ų6032 Ų3232%0.32119%0.186SC..THydrogen-bonded Turntrans-54.6-30.6-176.2-63.8-107000114.4V171 R234V171-D205 WeakPolarHBondContact O-CB 3.4Å; D205-R234 WeakPolarHBondContact OD1-CD 3.46Å; D205-R234 IonicContact OD1-CZ 2.71Å; D205-R234 IonicContact OD1-NE 2.76Å; D205-R234 PolarHBondContact OD1-NE 3.48Å; D205-R234 IonicContact OD1-NH2 2.68Å; D205-R234 IonicContact OD2-CZ 2.85Å; D205-R234 IonicContact OD2-NE 3.24Å; D205-R234 PolarHBondContact OD2-NE 2.89Å; D205-R234 IonicContact OD2-NH2 3.12Å; D205-R234 PolarHBondContact OD2-NH2 3.38Å
206L96.9Very high98.2Very high105 Ų10524.2 Ų24.255%0.5515%0.149SC..THydrogen-bonded Turntrans-106.911.1174-60.7-173.5000114.4G172 F173 D204 M208G172-L206 WeakPolarHBondContact O-CB 3.28Å; G172-L206 WeakPolarHBondContact O-CG 3.37Å; G172-L206 PolarHBondContact O-N 3.37Å; F173-L206 HydrophobicContact CB-CD1 4.19Å; F173-L206 WeakPolarHBondContact O-CD1 3.27Å; D204-L206 PolarHBondContact O-N 3.18Å; L206-M208 VanDerWaalsContact C-N 3.3Å; L206-M208 HydrophobicContact CB-CE 3.63Å; L206-M208 HydrophobicContact CD1-CE 3.66Å; L206-M208 HydrophobicContact CG-CE 4.3Å; L206-M208 PolarHBondContact O-N 2.55Å
207G96.8Very high98.2Very high57 Ų5723.1 Ų23.159%0.58814%0.144SC*.SBendtrans67.926.8-178.800000113.9D204D204-G207 PolarHBondContact O-N 2.88Å; D204-G207 WeakPolarHBondContact OD1-CA 3.49Å
208M97.4Very high98.2Very high46 Ų4627.2 Ų27.223%0.22716%0.16CC..  trans-115.92.9-174.8-68.2-167.8-74.200113.7T174 T175 D204 L206 T210 A211 N212T174-M208 WeakPolarHBondContact O-CE 3.42Å; T175-M208 HydrophobicContact CG2-CE 4.34Å; D204-M208 PolarHBondContact OD1-N 2.81Å; L206-M208 VanDerWaalsContact C-N 3.3Å; L206-M208 HydrophobicContact CB-CE 3.63Å; L206-M208 HydrophobicContact CD1-CE 3.66Å; L206-M208 HydrophobicContact CG-CE 4.3Å; L206-M208 PolarHBondContact O-N 2.55Å; M208-T210 VanDerWaalsContact C-N 3.34Å; M208-T210 PolarHBondContact O-N 3.21Å; M208-A211 PolarHBondContact O-N 2.69Å; M208-A211 VanDerWaalsContact O-N 3.07Å; M208-N212 WeakPolarHBondContact O-CB 3.4Å; M208-N212 VanDerWaalsContact O-CG 3.3Å; M208-N212 PolarHBondContact O-N 3.17Å
209A98.5Very high98.1Very high1 Ų129 Ų291%0.00817%0.171CC..Hα-helixtrans-57.1-45.5-171.800000112.7C202 H203 D204 N212 T213 V238C202-A209 HydrophobicContact CB-CB 3.88Å; H203-A209 WeakPolarHBondContact O-CB 3.29Å; D204-A209 HydrophobicContact CB-CB 3.76Å; D204-A209 WeakPolarHBondContact OD1-CB 3.49Å; D204-A209 PolarHBondContact OD1-N 2.9Å; A209-N212 PolarHBondContact O-N 3.17Å; A209-T213 VanDerWaalsContact O-CB 3.3Å; A209-T213 WeakPolarHBondContact O-CB 3.32Å; A209-T213 PolarHBondContact O-N 3.19Å; A209-T213 PolarHBondContact O-OG1 3.08Å; A209-V238 HydrophobicContact CB-CB 3.86Å; A209-V238 HydrophobicContact CB-CG2 4.37Å
210T98.6Very high98.1Very high31 Ų3130.6 Ų30.619%0.1919%0.186CC..Hα-helixtrans-62.6-44.4176.9-61.40000111.7M208 L214 E242 I243M208-T210 VanDerWaalsContact C-N 3.34Å; M208-T210 PolarHBondContact O-N 3.21Å; T210-L214 HydrophobicContact CG2-CD1 4.05Å; T210-L214 WeakPolarHBondContact O-CB 3.41Å; T210-L214 VanDerWaalsContact O-CG 3.29Å; T210-L214 WeakPolarHBondContact O-CG 3.43Å; T210-L214 PolarHBondContact O-N 3.26Å; T210-E242 HydrophobicContact CG2-CB 4.07Å; T210-E242 PolarHBondContact OG1-OE2 2.76Å; T210-I243 HydrophobicContact CG2-CD1 3.89Å
211A98.5Very high98Very high45 Ų4530.6 Ų30.637%0.37219%0.186SC..Hα-helixtrans-67.6-41.418000000112.3P176 M208 A215P176-A211 HydrophobicContact CB-CB 4.49Å; P176-A211 HydrophobicContact CG-CB 3.69Å; M208-A211 PolarHBondContact O-N 2.69Å; M208-A211 VanDerWaalsContact O-N 3.07Å; A211-A215 WeakPolarHBondContact O-CB 3.49Å; A211-A215 PolarHBondContact O-N 2.83Å
212N98.6Very high98Very high0 Ų030.8 Ų30.80%019%0.191CC..Hα-helixtrans-63.1-48.4176.4-70.5-9.1000110.4T174 P176 Y179 C202 M208 A209 L214 A215 A216T174-N212 VanDerWaalsContact CG2-ND2 3.31Å; T174-N212 WeakPolarHBondContact CG2-ND2 3.48Å; T174-N212 PolarHBondContact O-ND2 2.92Å; P176-N212 VanDerWaalsContact CA-OD1 3.22Å; P176-N212 WeakPolarHBondContact CA-OD1 3.23Å; P176-N212 WeakPolarHBondContact CD-OD1 3.46Å; P176-N212 WeakPolarHBondContact CG-OD1 3.38Å; Y179-N212 HydrophobicContact CD1-CB 3.8Å; Y179-N212 VanDerWaalsContact CD1-O 3.28Å; Y179-N212 WeakPolarHBondContact CD1-O 3.37Å; Y179-N212 HydrophobicContact CE1-CB 4.28Å; Y179-N212 HydrophobicContact CG-CB 4.28Å; C202-N212 HydrophobicContact CB-CB 4.5Å; M208-N212 WeakPolarHBondContact O-CB 3.4Å; M208-N212 VanDerWaalsContact O-CG 3.3Å; M208-N212 PolarHBondContact O-N 3.17Å; A209-N212 PolarHBondContact O-N 3.17Å; N212-L214 PolarHBondContact O-N 2.77Å; N212-A215 WeakPolarHBondContact O-CB 3.32Å; N212-A215 PolarHBondContact O-N 2.89Å; N212-A215 VanDerWaalsContact O-N 3.09Å; N212-A216 PolarHBondContact O-N 3.16Å
213T98.7Very high98Very high0 Ų030.9 Ų30.90%019%0.191CC..Hα-helixtrans-57.9-46.6177.9-61.40000112.2P200 C202 A209 A215 A216 I217 V224 V238 I243P200-T213 HydrophobicContact CB-CG2 4.49Å; P200-T213 HydrophobicContact CG-CG2 3.99Å; C202-T213 PolarHBondContact SG-OG1 3.35Å; A209-T213 VanDerWaalsContact O-CB 3.3Å; A209-T213 WeakPolarHBondContact O-CB 3.32Å; A209-T213 PolarHBondContact O-N 3.19Å; A209-T213 PolarHBondContact O-OG1 3.08Å; T213-A215 VanDerWaalsContact C-N 3.31Å; T213-A215 PolarHBondContact O-N 3.26Å; T213-A216 WeakPolarHBondContact O-CB 3.41Å; T213-A216 PolarHBondContact O-N 3.39Å; T213-I217 HydrophobicContact CG2-CD1 4.2Å; T213-I217 WeakPolarHBondContact O-CG1 3.47Å; T213-I217 PolarHBondContact O-N 2.83Å; T213-V224 HydrophobicContact CG2-CB 4.25Å; T213-V224 HydrophobicContact CG2-CG2 3.34Å; T213-V238 HydrophobicContact CG2-CG2 4.41Å; T213-I243 HydrophobicContact CG2-CD1 3.59Å; T213-I243 HydrophobicContact CG2-CG1 3.94Å; T213-I243 HydrophobicContact CG2-CG2 4.41Å
214L98.5Very high98Very high17 Ų1730.4 Ų30.49%0.08919%0.189CC..Hα-helixtrans-65.2-34.3176.9-70.2169.9000112.5T210 N212 I217 K218 I243 A246 L247 Y254T210-L214 HydrophobicContact CG2-CD1 4.05Å; T210-L214 WeakPolarHBondContact O-CB 3.41Å; T210-L214 VanDerWaalsContact O-CG 3.29Å; T210-L214 WeakPolarHBondContact O-CG 3.43Å; T210-L214 PolarHBondContact O-N 3.26Å; N212-L214 PolarHBondContact O-N 2.77Å; L214-I217 HydrophobicContact CD2-CD1 4.49Å; L214-I217 PolarHBondContact O-N 2.65Å; L214-K218 WeakPolarHBondContact O-CB 3.45Å; L214-K218 PolarHBondContact O-N 3.32Å; L214-I243 HydrophobicContact CD2-CD1 4.11Å; L214-I243 HydrophobicContact CD2-CG2 4.45Å; L214-I243 HydrophobicContact CG-CD1 3.88Å; L214-A246 HydrophobicContact CD1-CB 4.02Å; L214-A246 HydrophobicContact CD2-CB 4.01Å; L214-L247 HydrophobicContact CD2-CD2 4.16Å; L214-Y254 HydrophobicContact CB-CE1 4Å; L214-Y254 HydrophobicContact CD2-CE1 4.23Å; L214-Y254 HydrophobicContact CD2-CE2 3.98Å
215A98.5Very high98Very high14 Ų1428 Ų2812%0.11618%0.176CC..Hα-helixtrans-67.3-37.8173.700000112.4P176 A211 N212 T213 K218 N219P176-A215 HydrophobicContact CB-CB 3.97Å; P176-A215 WeakPolarHBondContact O-CB 3.46Å; A211-A215 WeakPolarHBondContact O-CB 3.49Å; A211-A215 PolarHBondContact O-N 2.83Å; N212-A215 WeakPolarHBondContact O-CB 3.32Å; N212-A215 PolarHBondContact O-N 2.89Å; N212-A215 VanDerWaalsContact O-N 3.09Å; T213-A215 VanDerWaalsContact C-N 3.31Å; T213-A215 PolarHBondContact O-N 3.26Å; A215-K218 PolarHBondContact O-N 3.45Å; A215-N219 PolarHBondContact O-N 3.18Å; A215-N219 VanDerWaalsContact O-N 3.12Å; A215-N219 PolarHBondContact O-ND2 3.14Å
216A98.5Very high98.1Very high0 Ų025.2 Ų25.20%016%0.161CC..Hα-helixtrans-63.7-44.9172.500000111.9Y179 F183 P200 N212 T213 K218 N219 G220 A221Y179-A216 HydrophobicContact CD1-CB 3.93Å; Y179-A216 HydrophobicContact CE1-CB 3.76Å; F183-A216 HydrophobicContact CB-CB 4.48Å; F183-A216 HydrophobicContact CD1-CB 3.97Å; F183-A216 HydrophobicContact CD2-CB 3.47Å; F183-A216 VanDerWaalsContact CD2-CB 3.47Å; F183-A216 HydrophobicContact CE1-CB 4.05Å; F183-A216 HydrophobicContact CE2-CB 3.6Å; F183-A216 HydrophobicContact CG-CB 3.68Å; F183-A216 HydrophobicContact CZ-CB 3.89Å; P200-A216 HydrophobicContact CB-CB 3.76Å; P200-A216 HydrophobicContact CG-CB 3.86Å; N212-A216 PolarHBondContact O-N 3.16Å; T213-A216 WeakPolarHBondContact O-CB 3.41Å; T213-A216 PolarHBondContact O-N 3.39Å; A216-K218 VanDerWaalsContact C-N 3.35Å; A216-K218 PolarHBondContact O-N 2.66Å; A216-N219 CarbonylContact O-C 3.52Å; A216-N219 PolarHBondContact O-N 2.8Å; A216-G220 PolarHBondContact O-N 3.41Å; A216-G220 VanDerWaalsContact O-N 3.13Å; A216-A221 HydrophobicContact CB-CB 4.11Å; A216-A221 WeakPolarHBondContact O-CB 3.09Å; A216-A221 PolarHBondContact O-N 2.93Å
217I98.2Very high98.2Very high2 Ų220.2 Ų20.21%0.0114%0.135CC..Hα-helixtrans-59.4-46175.3-67.5167.4000110.6R2 V4 T213 L214 N219 G220 I243 L247 A256R2-I217 PolarHBondContact NH2-O 2.92Å; V4-I217 HydrophobicContact CG1-CD1 4.3Å; V4-I217 HydrophobicContact CG2-CG2 3.94Å; T213-I217 HydrophobicContact CG2-CD1 4.2Å; T213-I217 WeakPolarHBondContact O-CG1 3.47Å; T213-I217 PolarHBondContact O-N 2.83Å; L214-I217 HydrophobicContact CD2-CD1 4.49Å; L214-I217 PolarHBondContact O-N 2.65Å; I217-N219 PolarHBondContact O-N 2.94Å; I217-G220 PolarHBondContact O-N 2.61Å; I217-I243 HydrophobicContact CD1-CG2 3.85Å; I217-L247 HydrophobicContact CD1-CD1 4.26Å; I217-L247 HydrophobicContact CD1-CD2 4.21Å; I217-L247 HydrophobicContact CG2-CD2 4.01Å; I217-A256 HydrophobicContact CG2-CB 4.39Å
218K97.4Very high98.3Very high117 Ų11717.5 Ų17.551%0.50911%0.107SC..Hα-helixtrans-58.4-31.3176.3-175.8179.2174.8-174.50112.6L214 A215 A216 Y253 Y254L214-K218 WeakPolarHBondContact O-CB 3.45Å; L214-K218 PolarHBondContact O-N 3.32Å; A215-K218 PolarHBondContact O-N 3.45Å; A216-K218 VanDerWaalsContact C-N 3.35Å; A216-K218 PolarHBondContact O-N 2.66Å; K218-Y253 HydrophobicContact CD-CE1 4.26Å; K218-Y253 PolarHBondContact NZ-OH 3.43Å; K218-Y254 HydrophobicContact CB-CD1 4.3Å; K218-Y254 HydrophobicContact CB-CE1 4.37Å
219N97.8Very high98.3Very high48 Ų4816.5 Ų16.526%0.25710%0.102SC..THydrogen-bonded Turntrans-94.912.5179.1-73.9-77.4000114G180 F183 K184 I187 A215 A216 I217G180-N219 VanDerWaalsContact CA-ND2 3.32Å; G180-N219 WeakPolarHBondContact CA-ND2 3.34Å; G180-N219 VanDerWaalsContact O-CB 3.23Å; G180-N219 WeakPolarHBondContact O-CB 3.42Å; F183-N219 HydrophobicContact CB-CB 4.19Å; K184-N219 HydrophobicContact CB-CB 4.1Å; I187-N219 WeakPolarHBondContact CD1-O 3.11Å; A215-N219 PolarHBondContact O-N 3.18Å; A215-N219 VanDerWaalsContact O-N 3.12Å; A215-N219 PolarHBondContact O-ND2 3.14Å; A216-N219 CarbonylContact O-C 3.52Å; A216-N219 PolarHBondContact O-N 2.8Å; I217-N219 PolarHBondContact O-N 2.94Å
220G97.1Very high98.2Very high32 Ų3217.1 Ų17.133%0.3311%0.109SC..THydrogen-bonded Turntrans113.81.1166.400000116.2A216 I217 G222A216-G220 PolarHBondContact O-N 3.41Å; A216-G220 VanDerWaalsContact O-N 3.13Å; I217-G220 PolarHBondContact O-N 2.61Å; G220-G222 PolarHBondContact O-N 2.85Å
221A98.1Very high98.1Very high0 Ų016 Ų160%010%0.102CC..  trans-61.1123.6178.600000112.8R2 F183 F198 P200 A216R2-A221 VanDerWaalsContact NH1-C 3.32Å; R2-A221 PolarHBondContact NH1-O 3.23Å; R2-A221 PolarHBondContact NH2-O 3.1Å; F183-A221 HydrophobicContact CD1-CB 3.61Å; F183-A221 HydrophobicContact CE1-CB 3.57Å; F198-A221 CarbonylContact O-C 3.5Å; F198-A221 WeakPolarHBondContact O-CA 3.16Å; P200-A221 VanDerWaalsContact CD-CB 3.46Å; P200-A221 HydrophobicContact CG-CB 4.23Å; A216-A221 HydrophobicContact CB-CB 4.11Å; A216-A221 WeakPolarHBondContact O-CB 3.09Å; A216-A221 PolarHBondContact O-N 2.93Å
222G98Very high98Very high12 Ų1214 Ų1412%0.1249%0.085CC..  trans-92.2-13.2-173.700000116.1R2 V4 E5 F198 G220R2-G222 VanDerWaalsContact NH1-CA 3.29Å; V4-G222 WeakPolarHBondContact CA-O 3.46Å; E5-G222 PolarHBondContact N-O 2.85Å; F198-G222 PolarHBondContact O-N 3.44Å; G220-G222 PolarHBondContact O-N 2.85Å
223R98.5Very high97.7Very high2 Ų217.4 Ų17.41%0.00810%0.101CC..EExtended strand (participates in β ladder)trans-128.1166.1173.7177.5175-77.1-168.8-7.1108.8E5 L7 Q94 E136 Y164 I197 F198 S199 P200E5-R223 HydrophobicContact CB-CB 4.2Å; E5-R223 HydrophobicContact CB-CG 4.22Å; E5-R223 CarbonylContact O-C 3.52Å; E5-R223 WeakPolarHBondContact O-CA 3.45Å; E5-R223 IonicContact OE2-CZ 3.01Å; E5-R223 IonicContact OE2-NE 2.61Å; E5-R223 PolarHBondContact OE2-NE 3.43Å; E5-R223 VanDerWaalsContact OE2-NE 3.11Å; E5-R223 IonicContact OE2-NH2 3.98Å; E5-R223 PolarHBondContact OE2-NH2 3.12Å; L7-R223 HydrophobicContact CB-CG 4.17Å; Q94-R223 VanDerWaalsContact OE1-NH1 3.17Å; E136-R223 IonicContact OE2-CZ 3.01Å; E136-R223 IonicContact OE2-NH1 2.72Å; E136-R223 PolarHBondContact OE2-NH1 3.3Å; Y164-R223 VanDerWaalsContact CE1-NE 3.29Å; Y164-R223 PolarHBondContact OH-NH2 2.88Å; I197-R223 HydrophobicContact CG2-CB 3.91Å; F198-R223 PolarHBondContact O-N 3.14Å; F198-R223 VanDerWaalsContact O-N 3.14Å; S199-R223 WeakPolarHBondContact OG-CG 3.41Å; P200-R223 WeakPolarHBondContact CD-O 3.2Å
224V98.6Very high97.5Very high0 Ų023 Ų230%012%0.122CC..EExtended strand (participates in β ladder)trans-134140.5163.854.60000108.5V4 E5 F6 L7 P200 T213 V238 L240 I243V4-V224 HydrophobicContact CG1-CG1 4.24Å; E5-V224 PolarHBondContact O-N 3.46Å; F6-V224 HydrophobicContact CB-CG1 4.32Å; F6-V224 HydrophobicContact CD1-CG1 3.7Å; F6-V224 HydrophobicContact CD2-CG1 3.86Å; F6-V224 HydrophobicContact CE1-CG1 3.86Å; F6-V224 HydrophobicContact CE2-CG1 3.99Å; F6-V224 HydrophobicContact CG-CG1 3.7Å; F6-V224 HydrophobicContact CZ-CG1 4Å; L7-V224 PolarHBondContact N-O 3.49Å; P200-V224 HydrophobicContact CG-CB 4.49Å; P200-V224 HydrophobicContact CG-CG2 4.49Å; T213-V224 HydrophobicContact CG2-CB 4.25Å; T213-V224 HydrophobicContact CG2-CG2 3.34Å; V224-V238 HydrophobicContact CG2-CG1 4.45Å; V224-L240 HydrophobicContact CG1-CD2 4.37Å; V224-L240 HydrophobicContact CG2-CD2 4.23Å; V224-I243 HydrophobicContact CG1-CG2 4.35Å; V224-I243 HydrophobicContact CG2-CG2 4.47Å
225E98.7Very high97.4Very high0 Ų024.8 Ų24.80%014%0.139CC..EExtended strand (participates in β ladder)trans-112.8136170.6-75.5165.5-127.600110.9L7 T9 N166 S199 P200 H201 V238L7-E225 HydrophobicContact CB-CG 3.78Å; L7-E225 HydrophobicContact CD1-CG 4.19Å; L7-E225 HydrophobicContact CD2-CG 3.72Å; L7-E225 HydrophobicContact CG-CG 4.06Å; L7-E225 WeakPolarHBondContact O-CA 3.47Å; T9-E225 HydrophobicContact CG2-CB 4.48Å; N166-E225 VanDerWaalsContact CB-OE1 3.32Å; N166-E225 WeakPolarHBondContact CB-OE1 3.35Å; N166-E225 PolarHBondContact ND2-OE1 2.95Å; N166-E225 PolarHBondContact ND2-OE2 3.3Å; N166-E225 PolarHBondContact OD1-OE1 2.85Å; S199-E225 WeakPolarHBondContact CB-OE1 3.44Å; S199-E225 WeakPolarHBondContact OG-CG 3.23Å; S199-E225 PolarHBondContact OG-OE1 3.15Å; P200-E225 PolarHBondContact O-N 3.15Å; H201-E225 HydrophobicContact CB-CB 3.94Å; H201-E225 IonicContact CE1-OE2 2.76Å; H201-E225 IonicContact CG-OE2 2.78Å; H201-E225 WeakPolarHBondContact ND1-CB 3.48Å; H201-E225 IonicContact ND1-OE2 3.61Å; H201-E225 PolarHBondContact ND1-OE2 2.96Å; E225-V238 WeakPolarHBondContact O-CG1 3.34Å
226G98.6Very high97.3Very high0 Ų024.1 Ų24.10%013%0.134CC..EExtended strand (participates in β ladder)trans-178-167.3177.700000111.4L7 T9 V238 L240L7-G226 PolarHBondContact O-N 2.89Å; T9-G226 PolarHBondContact N-O 3.32Å; T9-G226 PolarHBondContact OG1-O 3.07Å; G226-V238 WeakPolarHBondContact CA-O 3.3Å; G226-L240 WeakPolarHBondContact O-CD1 3.14Å
227T98.7Very high97.3Very high0 Ų024.3 Ų24.30%014%0.135CC..BIsolated β-bridgetrans-127158.8179.562.90000110.9T9 T10 G230 I231 N237 V238 A239 L240T9-T227 WeakPolarHBondContact OG1-CG2 3.38Å; T10-T227 WeakPolarHBondContact OG1-CA 3.15Å; T227-G230 WeakPolarHBondContact OG1-CA 3.2Å; T227-I231 WeakPolarHBondContact CB-O 3.44Å; T227-I231 HydrophobicContact CG2-CG1 4.42Å; T227-I231 WeakPolarHBondContact CG2-O 3.4Å; T227-I231 PolarHBondContact OG1-N 3.41Å; T227-I231 PolarHBondContact OG1-O 3.12Å; T227-N237 HydrophobicContact CG2-CB 3.94Å; T227-V238 PolarHBondContact N-O 2.91Å; T227-V238 VanDerWaalsContact N-O 3.08Å; T227-A239 WeakPolarHBondContact O-CA 3.44Å; T227-L240 PolarHBondContact O-N 2.95Å
228V98.1Very high97.3Very high1 Ų124.2 Ų24.21%0.00614%0.135CC..G310 helixtrans-73.5139.8168.6-178.90000109.2T10 L34 W37 G230 T268 I272T10-V228 PolarHBondContact OG1-N 2.57Å; T10-V228 VanDerWaalsContact OG1-N 3.11Å; L34-V228 HydrophobicContact CD2-CG2 3.88Å; W37-V228 HydrophobicContact CE3-CG2 4.22Å; W37-V228 HydrophobicContact CH2-CG2 4.16Å; W37-V228 HydrophobicContact CZ3-CG2 3.55Å; V228-G230 PolarHBondContact O-N 3.47Å; V228-T268 HydrophobicContact CG1-CG2 4.4Å; V228-T268 HydrophobicContact CG2-CG2 4.15Å; V228-I272 HydrophobicContact CB-CD1 3.45Å; V228-I272 VanDerWaalsContact CB-CD1 3.45Å; V228-I272 HydrophobicContact CG1-CD1 3.81Å; V228-I272 HydrophobicContact CG2-CD1 3.62Å
229N97.5Very high97.4Very high25 Ų2518.9 Ų18.913%0.13411%0.112CC..G310 helixtrans67.14.1-175.8-55.9-21.6000114.4I231 E241 S269N229-I231 VanDerWaalsContact C-N 3.3Å; N229-I231 HydrophobicContact CB-CG2 4.38Å; N229-I231 PolarHBondContact O-N 2.93Å; N229-E241 VanDerWaalsContact CA-OE1 3.28Å; N229-E241 WeakPolarHBondContact CA-OE1 3.25Å; N229-E241 PolarHBondContact N-OE1 2.62Å; N229-E241 PolarHBondContact N-OE2 3.39Å; N229-S269 PolarHBondContact ND2-O 2.96Å; N229-S269 VanDerWaalsContact OD1-CB 3.23Å; N229-S269 WeakPolarHBondContact OD1-CB 3.46Å; N229-S269 PolarHBondContact OD1-OG 3.23Å
230G97.7Very high97.4Very high14 Ų1416.6 Ų16.614%0.14410%0.1CC..G310 helixtrans66.528.5-177.500000113.4T227 V228 G236 N237T227-G230 WeakPolarHBondContact OG1-CA 3.2Å; V228-G230 PolarHBondContact O-N 3.47Å; G230-G236 VanDerWaalsContact O-CA 3.28Å; G230-G236 WeakPolarHBondContact O-CA 3.42Å; G230-N237 VanDerWaalsContact CA-O 3.27Å; G230-N237 WeakPolarHBondContact CA-O 3.44Å
231I96.7Very high97.5Very high8 Ų815.1 Ų15.14%0.0419%0.085CC..  trans-69.6156.5172.465.4168.2000111T10 F22 T227 N229 N237 I272 I278T10-I231 HydrophobicContact CG2-CD1 3.79Å; T10-I231 HydrophobicContact CG2-CG1 4.4Å; F22-I231 HydrophobicContact CZ-CD1 4.33Å; T227-I231 WeakPolarHBondContact CB-O 3.44Å; T227-I231 HydrophobicContact CG2-CG1 4.42Å; T227-I231 WeakPolarHBondContact CG2-O 3.4Å; T227-I231 PolarHBondContact OG1-N 3.41Å; T227-I231 PolarHBondContact OG1-O 3.12Å; N229-I231 VanDerWaalsContact C-N 3.3Å; N229-I231 HydrophobicContact CB-CG2 4.38Å; N229-I231 PolarHBondContact O-N 2.93Å; I231-N237 PolarHBondContact O-N 3.17Å; I231-N237 PolarHBondContact O-ND2 3.16Å; I231-N237 VanDerWaalsContact O-ND2 3.16Å; I231-I272 HydrophobicContact CD1-CG2 4.19Å; I231-I278 HydrophobicContact CG2-CD1 3.89Å
232G95.6Very high97.5Very high1 Ų116.9 Ų16.91%0.019%0.093CC..SBendtrans156.7-167.3178.300000113.3D13 T17 N237D13-G232 WeakPolarHBondContact O-CA 3.4Å; T17-G232 WeakPolarHBondContact OG1-CA 3.27Å; T17-G232 PolarHBondContact OG1-N 3.36Å; T17-G232 PolarHBondContact OG1-O 3.4Å; G232-N237 WeakPolarHBondContact CA-ND2 3.46Å
233E91.7Very high97.5Very high73 Ų7316.3 Ų16.334%0.3419%0.087SC..SBendtrans-57.3136.6170.2-83-79.2133.800112.2Q16 A235 G236Q16-E233 HydrophobicContact CB-CG 3.81Å; Q16-E233 WeakPolarHBondContact CB-OE1 3.47Å; Q16-E233 VanDerWaalsContact OE1-CG 3.29Å; E233-A235 PolarHBondContact O-N 3.36Å; E233-G236 WeakPolarHBondContact O-CA 3.4Å; E233-G236 PolarHBondContact O-N 3.34Å
234R94.7Very high97.5Very high116 Ų11616.2 Ų16.244%0.4389%0.086SC..THydrogen-bonded Turntrans57.3-110.7174.5-51.5176.3-54.2-71.9-5.9113T170 D205T170-R234 PolarHBondContact O-NH2 3.03Å; D205-R234 WeakPolarHBondContact OD1-CD 3.46Å; D205-R234 IonicContact OD1-CZ 2.71Å; D205-R234 IonicContact OD1-NE 2.76Å; D205-R234 PolarHBondContact OD1-NE 3.48Å; D205-R234 IonicContact OD1-NH2 2.68Å; D205-R234 IonicContact OD2-CZ 2.85Å; D205-R234 IonicContact OD2-NE 3.24Å; D205-R234 PolarHBondContact OD2-NE 2.89Å; D205-R234 IonicContact OD2-NH2 3.12Å; D205-R234 PolarHBondContact OD2-NH2 3.38Å
235A95.9Very high97.4Very high55 Ų5516.3 Ų16.346%0.4559%0.087SC..THydrogen-bonded Turntrans-80-6.3176.400000112.8D204 E233D204-A235 HydrophobicContact CB-CB 4.26Å; D204-A235 WeakPolarHBondContact O-CB 3.12Å; E233-A235 PolarHBondContact O-N 3.36Å
236G97.1Very high97.4Very high1 Ų117.4 Ų17.41%0.0110%0.096CC..  trans100.2-173.617700000114.1H203 D204 G230 E233H203-G236 VanDerWaalsContact CA-O 3.29Å; H203-G236 WeakPolarHBondContact CA-O 3.35Å; H203-G236 PolarHBondContact ND1-O 2.91Å; D204-G236 PolarHBondContact N-O 3.42Å; G230-G236 VanDerWaalsContact O-CA 3.28Å; G230-G236 WeakPolarHBondContact O-CA 3.42Å; E233-G236 WeakPolarHBondContact O-CA 3.4Å; E233-G236 PolarHBondContact O-N 3.34Å
237N98.4Very high97.3Very high3 Ų317.5 Ų17.52%0.01610%0.096CC..BIsolated β-bridgetrans-97169.8173.8-68.4-74.5000110.4D13 H201 C202 H203 T227 G230 I231 G232 A239D13-N237 PolarHBondContact OD1-ND2 3.49Å; H201-N237 PolarHBondContact NE2-OD1 2.93Å; C202-N237 CarbonylContact O-C 3.56Å; H203-N237 PolarHBondContact CE1-OD1 2.82Å; T227-N237 HydrophobicContact CG2-CB 3.94Å; G230-N237 VanDerWaalsContact CA-O 3.27Å; G230-N237 WeakPolarHBondContact CA-O 3.44Å; I231-N237 PolarHBondContact O-N 3.17Å; I231-N237 PolarHBondContact O-ND2 3.16Å; I231-N237 VanDerWaalsContact O-ND2 3.16Å; G232-N237 WeakPolarHBondContact CA-ND2 3.46Å; N237-A239 PolarHBondContact O-N 3.11Å
238V98.6Very high97.2Very high1 Ų120.8 Ų20.81%0.00611%0.114CC..  trans-53.2132.5165.964.10000110.6C202 A209 T213 V224 E225 G226 T227 L240 I243C202-V238 PolarHBondContact O-N 3.45Å; A209-V238 HydrophobicContact CB-CB 3.86Å; A209-V238 HydrophobicContact CB-CG2 4.37Å; T213-V238 HydrophobicContact CG2-CG2 4.41Å; V224-V238 HydrophobicContact CG2-CG1 4.45Å; E225-V238 WeakPolarHBondContact O-CG1 3.34Å; G226-V238 WeakPolarHBondContact CA-O 3.3Å; T227-V238 PolarHBondContact N-O 2.91Å; T227-V238 VanDerWaalsContact N-O 3.08Å; V238-L240 PolarHBondContact O-N 2.87Å; V238-I243 HydrophobicContact CG2-CD1 3.78Å; V238-I243 HydrophobicContact CG2-CG1 3.68Å
239A98.5Very high97.1Very high5 Ų523.1 Ų23.14%0.04113%0.126CC..BIsolated β-bridgetrans-74.5111.1176.900000110.8T227 N237 E241 E242 I243 K284T227-A239 WeakPolarHBondContact O-CA 3.44Å; N237-A239 PolarHBondContact O-N 3.11Å; A239-E241 WeakPolarHBondContact CB-OE1 3.36Å; A239-E241 PolarHBondContact O-N 3.2Å; A239-E242 HydrophobicContact CB-CB 4.28Å; A239-E242 HydrophobicContact CB-CG 3.79Å; A239-E242 WeakPolarHBondContact O-CB 3.16Å; A239-E242 PolarHBondContact O-N 3.28Å; A239-E242 VanDerWaalsContact O-N 3.08Å; A239-I243 PolarHBondContact O-N 3.01Å; A239-K284 VanDerWaalsContact CB-NZ 3.29Å
240L98.8Very high97Very high0 Ų027 Ų270%014%0.139CC..Hα-helixtrans-61.1-34-176.4-70-177.5000112.8F6 D8 W37 I39 V224 G226 T227 V238 E242 I243 A244F6-L240 HydrophobicContact CD1-CB 4.39Å; F6-L240 HydrophobicContact CD1-CD2 4.02Å; F6-L240 HydrophobicContact CE1-CD2 4.49Å; D8-L240 HydrophobicContact CB-CD1 3.91Å; W37-L240 HydrophobicContact CH2-CB 3.78Å; W37-L240 HydrophobicContact CZ3-CB 4.02Å; W37-L240 HydrophobicContact CZ3-CD1 4.42Å; I39-L240 HydrophobicContact CD1-CD1 4.1Å; V224-L240 HydrophobicContact CG1-CD2 4.37Å; V224-L240 HydrophobicContact CG2-CD2 4.23Å; G226-L240 WeakPolarHBondContact O-CD1 3.14Å; T227-L240 PolarHBondContact O-N 2.95Å; V238-L240 PolarHBondContact O-N 2.87Å; L240-E242 PolarHBondContact O-N 3.36Å; L240-I243 PolarHBondContact O-N 3.22Å; L240-A244 WeakPolarHBondContact O-CB 3.37Å; L240-A244 PolarHBondContact O-N 2.67Å
241E98.3Very high96.8Very high1 Ų130.1 Ų30.11%0.00515%0.15CC..Hα-helixtrans-62.7-33.1177.968.4-79.9-176.600112.4W37 N229 A239 V245 T265 K284 V286 V287W37-E241 HydrophobicContact CH2-CB 4.24Å; W37-E241 HydrophobicContact CZ2-CB 4.14Å; N229-E241 VanDerWaalsContact CA-OE1 3.28Å; N229-E241 WeakPolarHBondContact CA-OE1 3.25Å; N229-E241 PolarHBondContact N-OE1 2.62Å; N229-E241 PolarHBondContact N-OE2 3.39Å; A239-E241 WeakPolarHBondContact CB-OE1 3.36Å; A239-E241 PolarHBondContact O-N 3.2Å; E241-V245 WeakPolarHBondContact O-CG2 2.93Å; E241-V245 PolarHBondContact O-N 2.85Å; E241-V245 VanDerWaalsContact O-N 3.17Å; E241-T265 HydrophobicContact CB-CG2 3.56Å; E241-K284 IonicContact OE1-NZ 2.7Å; E241-K284 PolarHBondContact OE1-NZ 3.24Å; E241-V286 HydrophobicContact CB-CG1 4.37Å; E241-V286 HydrophobicContact CG-CB 4.33Å; E241-V286 HydrophobicContact CG-CG1 4.45Å; E241-V287 HydrophobicContact CB-CG1 4.37Å; E241-V287 HydrophobicContact CG-CG1 3.97Å; E241-V287 HydrophobicContact CG-CG2 4.29Å
242E98.4Very high96.6Very high36 Ų3635.2 Ų35.217%0.16818%0.177CC..Hα-helixtrans-70.9-41.3177.5-62.7-176.8-176.300111.1T210 A239 L240 A246 K284 A285 V286T210-E242 HydrophobicContact CG2-CB 4.07Å; T210-E242 PolarHBondContact OG1-OE2 2.76Å; A239-E242 HydrophobicContact CB-CB 4.28Å; A239-E242 HydrophobicContact CB-CG 3.79Å; A239-E242 WeakPolarHBondContact O-CB 3.16Å; A239-E242 PolarHBondContact O-N 3.28Å; A239-E242 VanDerWaalsContact O-N 3.08Å; L240-E242 PolarHBondContact O-N 3.36Å; E242-A246 WeakPolarHBondContact O-CB 3.35Å; E242-A246 PolarHBondContact O-N 2.8Å; E242-K284 IonicContact OE1-NZ 3.01Å; E242-K284 PolarHBondContact OE1-NZ 3.26Å; E242-A285 HydrophobicContact CG-CB 4.12Å; E242-V286 HydrophobicContact CG-CG2 4.42Å
243I98.6Very high96.6Very high0 Ų040.2 Ų40.20%020%0.197CC..Hα-helixtrans-66.9-45.7177.4-55.1-60.9000110.7F6 T210 T213 L214 I217 V224 V238 A239 L240 V245 A246 L247F6-I243 HydrophobicContact CE1-CB 4.06Å; F6-I243 HydrophobicContact CE1-CG2 4.05Å; F6-I243 HydrophobicContact CZ-CB 4.23Å; F6-I243 HydrophobicContact CZ-CG2 3.78Å; T210-I243 HydrophobicContact CG2-CD1 3.89Å; T213-I243 HydrophobicContact CG2-CD1 3.59Å; T213-I243 HydrophobicContact CG2-CG1 3.94Å; T213-I243 HydrophobicContact CG2-CG2 4.41Å; L214-I243 HydrophobicContact CD2-CD1 4.11Å; L214-I243 HydrophobicContact CD2-CG2 4.45Å; L214-I243 HydrophobicContact CG-CD1 3.88Å; I217-I243 HydrophobicContact CD1-CG2 3.85Å; V224-I243 HydrophobicContact CG1-CG2 4.35Å; V224-I243 HydrophobicContact CG2-CG2 4.47Å; V238-I243 HydrophobicContact CG2-CD1 3.78Å; V238-I243 HydrophobicContact CG2-CG1 3.68Å; A239-I243 PolarHBondContact O-N 3.01Å; L240-I243 PolarHBondContact O-N 3.22Å; I243-V245 PolarHBondContact O-N 2.73Å; I243-A246 PolarHBondContact O-N 2.64Å; I243-L247 HydrophobicContact CG2-CD1 4.19Å; I243-L247 HydrophobicContact CG2-CG 4.28Å; I243-L247 WeakPolarHBondContact O-CG 3.32Å; I243-L247 PolarHBondContact O-N 3.33Å
244A98.3Very high96.8Very high0 Ų038.7 Ų38.70%019%0.188CC..Hα-helixtrans-57.8-48.4179.900000111.8F6 W37 L240 N248 I260 L262F6-A244 HydrophobicContact CE1-CB 3.83Å; F6-A244 HydrophobicContact CZ-CB 3.99Å; W37-A244 HydrophobicContact CZ2-CB 4.48Å; L240-A244 WeakPolarHBondContact O-CB 3.37Å; L240-A244 PolarHBondContact O-N 2.67Å; A244-N248 PolarHBondContact O-N 3.08Å; A244-I260 HydrophobicContact CB-CB 4.1Å; A244-I260 HydrophobicContact CB-CG1 4.06Å; A244-I260 HydrophobicContact CB-CG2 3.78Å; A244-L262 HydrophobicContact CB-CD2 3.95Å
245V97.6Very high96.8Very high3 Ų339.6 Ų39.62%0.01820%0.197CC..Hα-helixtrans-70.2-40.5178.51740000111.4E241 I243 L247 N248 I249 L262 V286 I313 V318E241-V245 WeakPolarHBondContact O-CG2 2.93Å; E241-V245 PolarHBondContact O-N 2.85Å; E241-V245 VanDerWaalsContact O-N 3.17Å; I243-V245 PolarHBondContact O-N 2.73Å; V245-L247 VanDerWaalsContact C-N 3.35Å; V245-L247 PolarHBondContact O-N 2.89Å; V245-N248 PolarHBondContact O-N 2.93Å; V245-I249 HydrophobicContact CG1-CG1 3.85Å; V245-I249 WeakPolarHBondContact O-CB 3.43Å; V245-I249 WeakPolarHBondContact O-CG1 3.43Å; V245-I249 PolarHBondContact O-N 3.31Å; V245-L262 HydrophobicContact CG2-CD2 3.88Å; V245-V286 HydrophobicContact CB-CG1 4.33Å; V245-V286 HydrophobicContact CB-CG2 3.83Å; V245-V286 HydrophobicContact CG1-CG2 4.08Å; V245-V286 HydrophobicContact CG2-CB 4.47Å; V245-V286 HydrophobicContact CG2-CG1 3.56Å; V245-V286 HydrophobicContact CG2-CG2 4.01Å; V245-I313 HydrophobicContact CG1-CD1 3.53Å; V245-I313 HydrophobicContact CG1-CG1 3.61Å; V245-I313 HydrophobicContact CG1-CG2 4.31Å; V245-V318 HydrophobicContact CG2-CG1 3.89Å
246A97.6Very high96.7Very high22 Ų2237 Ų3718%0.18218%0.175CC..Hα-helixtrans-60.2-42.4177.300000112.5L214 E242 I243 N248 R250L214-A246 HydrophobicContact CD1-CB 4.02Å; L214-A246 HydrophobicContact CD2-CB 4.01Å; E242-A246 WeakPolarHBondContact O-CB 3.35Å; E242-A246 PolarHBondContact O-N 2.8Å; I243-A246 PolarHBondContact O-N 2.64Å; A246-N248 VanDerWaalsContact C-N 3.34Å; A246-R250 VanDerWaalsContact O-CB 3.27Å; A246-R250 WeakPolarHBondContact O-CB 3.23Å; A246-R250 PolarHBondContact O-N 3.48Å
247L97.1Very high96.6Very high2 Ų239.3 Ų39.31%0.0119%0.189CC..Hα-helixtrans-65.4-36.7177-67.9-177000112.5V4 F6 L214 I217 I243 V245 R250 E251 Y254 A256V4-L247 HydrophobicContact CB-CD1 4.06Å; V4-L247 HydrophobicContact CG1-CD1 4.18Å; V4-L247 HydrophobicContact CG2-CD1 4.28Å; F6-L247 HydrophobicContact CE2-CD1 4.01Å; F6-L247 HydrophobicContact CZ-CD1 4.03Å; L214-L247 HydrophobicContact CD2-CD2 4.16Å; I217-L247 HydrophobicContact CD1-CD1 4.26Å; I217-L247 HydrophobicContact CD1-CD2 4.21Å; I217-L247 HydrophobicContact CG2-CD2 4.01Å; I243-L247 HydrophobicContact CG2-CD1 4.19Å; I243-L247 HydrophobicContact CG2-CG 4.28Å; I243-L247 WeakPolarHBondContact O-CG 3.32Å; I243-L247 PolarHBondContact O-N 3.33Å; V245-L247 VanDerWaalsContact C-N 3.35Å; V245-L247 PolarHBondContact O-N 2.89Å; L247-R250 CarbonylContact O-C 3.51Å; L247-E251 WeakPolarHBondContact O-CA 3.42Å; L247-E251 PolarHBondContact O-N 3.03Å; L247-Y254 HydrophobicContact CD2-CD2 3.98Å; L247-Y254 HydrophobicContact CD2-CG 3.93Å; L247-A256 HydrophobicContact CD2-CB 4.34Å
248N96.1Very high96.6Very high69 Ų6940.6 Ų40.637%0.36920%0.199SC..Hα-helixtrans-72.3-48.3177.5-177.2-98.5000112.4A244 V245 A246 R250 L262A244-N248 PolarHBondContact O-N 3.08Å; V245-N248 PolarHBondContact O-N 2.93Å; A246-N248 VanDerWaalsContact C-N 3.34Å; N248-R250 VanDerWaalsContact C-N 3.28Å; N248-R250 PolarHBondContact O-N 2.79Å; N248-L262 HydrophobicContact CB-CD1 3.54Å; N248-L262 WeakPolarHBondContact OD1-CD1 3.11Å
249I95.1Very high96.5Very high51 Ų5145 Ų4526%0.26222%0.223SC..Hα-helixtrans-67.1-32.1-179.7-63.1-50.5000111.6V245 I312 I313 L317V245-I249 HydrophobicContact CG1-CG1 3.85Å; V245-I249 WeakPolarHBondContact O-CB 3.43Å; V245-I249 WeakPolarHBondContact O-CG1 3.43Å; V245-I249 PolarHBondContact O-N 3.31Å; I249-I312 WeakPolarHBondContact CD1-O 3.28Å; I249-I312 HydrophobicContact CG2-CB 4.44Å; I249-I312 HydrophobicContact CG2-CD1 4.44Å; I249-I313 HydrophobicContact CD1-CG1 4.34Å; I249-I313 HydrophobicContact CG1-CG1 4.02Å; I249-L317 HydrophobicContact CD1-CD2 3.78Å
250R95.3Very high96.5Very high105 Ų10545.5 Ų45.540%0.39622%0.224SC..THydrogen-bonded Turntrans-114.534.4-178.3-58.6-61-55.6-71.4-2112.4A246 L247 N248 D252 Y253 Y254A246-R250 VanDerWaalsContact O-CB 3.27Å; A246-R250 WeakPolarHBondContact O-CB 3.23Å; A246-R250 PolarHBondContact O-N 3.48Å; L247-R250 CarbonylContact O-C 3.51Å; N248-R250 VanDerWaalsContact C-N 3.28Å; N248-R250 PolarHBondContact O-N 2.79Å; R250-D252 WeakPolarHBondContact CA-OD1 3.38Å; R250-D252 IonicContact NE-OD1 3.68Å; R250-D252 PolarHBondContact O-N 3.2Å; R250-Y253 VanDerWaalsContact NH2-CB 3.33Å; R250-Y253 PolarHBondContact O-N 3.44Å; R250-Y254 HydrophobicContact CB-CD2 3.72Å; R250-Y254 HydrophobicContact CB-CE2 3.75Å; R250-Y254 WeakPolarHBondContact O-CD2 3.22Å; R250-Y254 PolarHBondContact O-N 2.99Å
251E93.6Very high96.4Very high80 Ų8048.8 Ų48.837%0.37424%0.244SC..Hα-helixtrans-54.2-37.1176.2-174-176.1162.100110.9M1 L247 Y253 Q255M1-E251 HydrophobicContact CE-CG 3.66Å; M1-E251 WeakPolarHBondContact CE-OE1 3.17Å; M1-E251 HydrophobicContact SD-CG 3.26Å; M1-E251 WeakPolarHBondContact SD-CG 3.43Å; L247-E251 WeakPolarHBondContact O-CA 3.42Å; L247-E251 PolarHBondContact O-N 3.03Å; E251-Y253 VanDerWaalsContact C-N 3.3Å; E251-Y253 PolarHBondContact O-N 3.04Å; E251-Q255 VanDerWaalsContact O-CA 3.22Å; E251-Q255 WeakPolarHBondContact O-CA 3.33Å; E251-Q255 PolarHBondContact O-N 3.13Å
252D93.3Very high96.4Very high116 Ų11649.4 Ų49.462%0.6225%0.247SC*.Hα-helixtrans-58.9-37.5176.171.3-45000113.5R250R250-D252 WeakPolarHBondContact CA-OD1 3.38Å; R250-D252 IonicContact NE-OD1 3.68Å; R250-D252 PolarHBondContact O-N 3.2Å
253Y95.4Very high96.2Very high106 Ų10651.7 Ų51.742%0.41626%0.261SS..Hα-helixtrans-91.6-45.5-173.9178.3-101000112.6K218 R250 E251K218-Y253 HydrophobicContact CD-CE1 4.26Å; K218-Y253 PolarHBondContact NZ-OH 3.43Å; R250-Y253 VanDerWaalsContact NH2-CB 3.33Å; R250-Y253 PolarHBondContact O-N 3.44Å; E251-Y253 VanDerWaalsContact C-N 3.3Å; E251-Y253 PolarHBondContact O-N 3.04Å
254Y95.5Very high96Very high41 Ų4153.1 Ų53.116%0.16127%0.267CS..Hα-helixtrans-81-19.6179.2-67.2-67.7000112.8L214 K218 L247 R250 A256L214-Y254 HydrophobicContact CB-CE1 4Å; L214-Y254 HydrophobicContact CD2-CE1 4.23Å; L214-Y254 HydrophobicContact CD2-CE2 3.98Å; K218-Y254 HydrophobicContact CB-CD1 4.3Å; K218-Y254 HydrophobicContact CB-CE1 4.37Å; L247-Y254 HydrophobicContact CD2-CD2 3.98Å; L247-Y254 HydrophobicContact CD2-CG 3.93Å; R250-Y254 HydrophobicContact CB-CD2 3.72Å; R250-Y254 HydrophobicContact CB-CE2 3.75Å; R250-Y254 WeakPolarHBondContact O-CD2 3.22Å; R250-Y254 PolarHBondContact O-N 2.99Å; Y254-A256 PolarHBondContact O-N 3.39Å
255Q94.6Very high96Very high135 Ų13553.2 Ų53.263%0.63127%0.268SS*.  trans5042-176.4-57.1-175.4-14.800111.5M1 R2 E251M1-Q255 WeakPolarHBondContact CG-O 3.48Å; R2-Q255 PolarHBondContact N-O 3.06Å; R2-Q255 VanDerWaalsContact N-O 3.17Å; E251-Q255 VanDerWaalsContact O-CA 3.22Å; E251-Q255 WeakPolarHBondContact O-CA 3.33Å; E251-Q255 PolarHBondContact O-N 3.13Å
256A95Very high95.7Very high0 Ų053.6 Ų53.60%027%0.27CS..EExtended strand (participates in β ladder)trans-135.5138.3-175.100000111.4R2 V4 I217 L247 Y254R2-A256 CarbonylContact O-C 3Å; R2-A256 WeakPolarHBondContact O-CA 3.21Å; V4-A256 HydrophobicContact CG2-CB 3.84Å; I217-A256 HydrophobicContact CG2-CB 4.39Å; L247-A256 HydrophobicContact CD2-CB 4.34Å; Y254-A256 PolarHBondContact O-N 3.39Å
257T95.4Very high95.3Very high49 Ų4955.5 Ų55.530%0.30128%0.277SS..EExtended strand (participates in β ladder)trans-113.7163.1173.661.10000110.7M1 R2 K3 V4M1-T257 HydrophobicContact CB-CG2 4.12Å; M1-T257 HydrophobicContact CG-CG2 3.96Å; M1-T257 HydrophobicContact SD-CG2 3.41Å; M1-T257 WeakPolarHBondContact SD-CG2 3.22Å; R2-T257 PolarHBondContact O-N 2.99Å; K3-T257 CarbonylContact C-O 3.56Å; K3-T257 WeakPolarHBondContact CA-O 3.07Å; V4-T257 PolarHBondContact N-O 3.05Å
258S96.7Very high95.1Very high31 Ų3155.4 Ų55.422%0.21728%0.277CS..  trans-135.8166.5169.969.70000110.9F6 I260F6-S258 VanDerWaalsContact CE2-CB 3.47Å; S258-I260 PolarHBondContact OG-N 3.42Å
259D97.3Very high95.1Very high94 Ų9452.1 Ų52.150%0.50326%0.259SS..  trans-85.84.7173.1-73.9-14.2000112.8K3 V261K3-D259 WeakPolarHBondContact CE-OD1 3.07Å; K3-D259 WeakPolarHBondContact CE-OD2 3.29Å; K3-D259 IonicContact NZ-OD1 2.96Å; K3-D259 PolarHBondContact NZ-OD1 3.45Å; K3-D259 IonicContact NZ-OD2 2.78Å; K3-D259 PolarHBondContact NZ-OD2 2.78Å; D259-V261 PolarHBondContact O-N 2.94Å
260I98.4Very high94.8Very high15 Ų1554 Ų548%0.07727%0.267CS..  trans-65125.9-175-60.3-65.9000110.2F6 W37 I39 A244 S258 L262F6-I260 HydrophobicContact CB-CD1 3.98Å; F6-I260 HydrophobicContact CD1-CD1 3.97Å; F6-I260 HydrophobicContact CD1-CG1 4.01Å; F6-I260 HydrophobicContact CD2-CD1 4.26Å; F6-I260 HydrophobicContact CD2-CG1 3.9Å; F6-I260 HydrophobicContact CE1-CG1 4.16Å; F6-I260 HydrophobicContact CE2-CG1 4.08Å; F6-I260 HydrophobicContact CG-CD1 3.81Å; F6-I260 HydrophobicContact CG-CG1 3.89Å; F6-I260 HydrophobicContact CZ-CG1 4.2Å; W37-I260 HydrophobicContact CD2-CG2 4.26Å; W37-I260 HydrophobicContact CG-CG2 4.38Å; W37-I260 HydrophobicContact CZ2-CG2 4.09Å; W37-I260 CarbonylContact O-C 3.56Å; W37-I260 WeakPolarHBondContact O-CA 3.41Å; I39-I260 HydrophobicContact CD1-CD1 3.91Å; A244-I260 HydrophobicContact CB-CB 4.1Å; A244-I260 HydrophobicContact CB-CG1 4.06Å; A244-I260 HydrophobicContact CB-CG2 3.78Å; S258-I260 PolarHBondContact OG-N 3.42Å; I260-L262 HydrophobicContact CG2-CD2 4.04Å; I260-L262 PolarHBondContact O-N 3.22Å; I260-L262 VanDerWaalsContact O-N 3.15Å
261V97.6Very high94.4Very high68 Ų6850.7 Ų50.741%0.41226%0.257SS..  trans-83.888175.2-173.60000108.2W37 D259 N263 E264W37-V261 PolarHBondContact O-N 3.28Å; D259-V261 PolarHBondContact O-N 2.94Å; V261-N263 PolarHBondContact O-N 3.45Å; V261-N263 VanDerWaalsContact O-N 3.09Å; V261-E264 HydrophobicContact CB-CG 4.18Å; V261-E264 HydrophobicContact CG1-CG 3.8Å; V261-E264 WeakPolarHBondContact O-CB 3.25Å; V261-E264 PolarHBondContact O-N 3.12Å
262L97.3Very high94.3Very high15 Ų1547 Ų478%0.07924%0.239CC..G310 helixtrans-53.9-35.5-171.1-67.8-179.2000114.2A244 V245 N248 I260 E264 T265 L317 V318A244-L262 HydrophobicContact CB-CD2 3.95Å; V245-L262 HydrophobicContact CG2-CD2 3.88Å; N248-L262 HydrophobicContact CB-CD1 3.54Å; N248-L262 WeakPolarHBondContact OD1-CD1 3.11Å; I260-L262 HydrophobicContact CG2-CD2 4.04Å; I260-L262 PolarHBondContact O-N 3.22Å; I260-L262 VanDerWaalsContact O-N 3.15Å; L262-E264 PolarHBondContact O-N 2.81Å; L262-T265 WeakPolarHBondContact O-CB 3.48Å; L262-T265 PolarHBondContact O-N 3.48Å; L262-T265 PolarHBondContact O-OG1 2.52Å; L262-L317 CarbonylContact C-O 3.51Å; L262-L317 HydrophobicContact CB-CD1 4.3Å; L262-L317 HydrophobicContact CB-CG 4.43Å; L262-L317 VanDerWaalsContact CB-O 3.23Å; L262-L317 WeakPolarHBondContact CB-O 3.23Å; L262-L317 HydrophobicContact CD1-CD1 3.81Å; L262-L317 HydrophobicContact CD1-CD2 4.33Å; L262-L317 HydrophobicContact CD1-CG 4.02Å; L262-V318 CarbonylContact O-C 3.53Å; L262-V318 VanDerWaalsContact O-CA 3.26Å; L262-V318 WeakPolarHBondContact O-CA 3.41Å
263N94.3Very high94Very high84 Ų8442.4 Ų42.445%0.44922%0.217SC..G310 helixtrans-62.8-17.3178.5-172-79.4000113.2V261 E316 L317 G319V261-N263 PolarHBondContact O-N 3.45Å; V261-N263 VanDerWaalsContact O-N 3.09Å; N263-E316 PolarHBondContact ND2-O 3.35Å; N263-L317 WeakPolarHBondContact CA-O 3.43Å; N263-L317 PolarHBondContact N-O 3.2Å; N263-G319 WeakPolarHBondContact O-CA 3.46Å
264E95.1Very high93.3Very high30 Ų3046 Ų4614%0.1423%0.229CC..G310 helixtrans-88.5-3.4176.2-61.8-71.3163.900112.7R33 K36 V261 L262 T268R33-E264 IonicContact CZ-OE2 2.75Å; R33-E264 IonicContact NH1-OE2 3.33Å; R33-E264 PolarHBondContact NH1-OE2 2.92Å; R33-E264 VanDerWaalsContact NH2-CB 3.35Å; R33-E264 PolarHBondContact NH2-O 3.49Å; R33-E264 IonicContact NH2-OE2 3.2Å; R33-E264 PolarHBondContact NH2-OE2 3.09Å; K36-E264 WeakPolarHBondContact CE-OE1 3.38Å; K36-E264 WeakPolarHBondContact CE-OE2 3.37Å; K36-E264 IonicContact NZ-OE1 2.75Å; K36-E264 PolarHBondContact NZ-OE1 2.91Å; K36-E264 IonicContact NZ-OE2 2.61Å; K36-E264 PolarHBondContact NZ-OE2 3.45Å; V261-E264 HydrophobicContact CB-CG 4.18Å; V261-E264 HydrophobicContact CG1-CG 3.8Å; V261-E264 WeakPolarHBondContact O-CB 3.25Å; V261-E264 PolarHBondContact O-N 3.12Å; L262-E264 PolarHBondContact O-N 2.81Å; E264-T268 WeakPolarHBondContact O-CB 3.48Å; E264-T268 PolarHBondContact O-N 2.85Å; E264-T268 VanDerWaalsContact O-N 3.11Å; E264-T268 PolarHBondContact O-OG1 2.89Å
265T97Very high92.7Very high1 Ų146.6 Ų46.61%0.00623%0.233CC..Hα-helixtrans-60.9-55.5-170.9-57.40000113.1W37 E241 L262 N267 T268 S269 V286 V287W37-T265 HydrophobicContact CZ2-CG2 4.06Å; W37-T265 PolarHBondContact NE1-OG1 2.93Å; E241-T265 HydrophobicContact CB-CG2 3.56Å; L262-T265 WeakPolarHBondContact O-CB 3.48Å; L262-T265 PolarHBondContact O-N 3.48Å; L262-T265 PolarHBondContact O-OG1 2.52Å; T265-N267 PolarHBondContact O-N 3Å; T265-T268 WeakPolarHBondContact O-CB 3.29Å; T265-T268 PolarHBondContact O-N 3.04Å; T265-T268 VanDerWaalsContact O-N 3.15Å; T265-S269 WeakPolarHBondContact O-CB 3.34Å; T265-S269 PolarHBondContact O-N 2.84Å; T265-V286 HydrophobicContact CG2-CG1 4.06Å; T265-V287 HydrophobicContact CG2-CG1 3.94Å
266V93.1Very high92.3Very high11 Ų1140.6 Ų40.67%0.06721%0.206CC..Hα-helixtrans-63-45.4-175.8169.70000111.7T268 S269 E270 V287 V318 V320V266-T268 PolarHBondContact O-N 3.44Å; V266-S269 WeakPolarHBondContact O-CB 3.47Å; V266-S269 PolarHBondContact O-N 3.17Å; V266-E270 HydrophobicContact CG1-CG 4.25Å; V266-E270 WeakPolarHBondContact O-CG 3.45Å; V266-E270 PolarHBondContact O-N 2.92Å; V266-V287 HydrophobicContact CG2-CG1 4.22Å; V266-V318 HydrophobicContact CG2-CB 4.16Å; V266-V318 HydrophobicContact CG2-CG2 3.79Å; V266-V318 WeakPolarHBondContact CG2-O 3.45Å; V266-V318 PolarHBondContact N-O 3.19Å; V266-V320 HydrophobicContact CG1-CG2 4.48Å; V266-V320 HydrophobicContact CG2-CG2 3.82Å
267N87.6Confident91.7Very high63 Ų6343.6 Ų43.634%0.33724%0.237SC..Hα-helixtrans-67.9-26179.2-48.8-72.8000112.3T265 L271T265-N267 PolarHBondContact O-N 3Å; N267-L271 WeakPolarHBondContact O-CB 3.31Å; N267-L271 PolarHBondContact O-N 3.07Å
268T93.9Very high91.3Very high0 Ų044.2 Ų44.20%024%0.238CC..Hα-helixtrans-70-45.9172.1-61.30000110.9R33 L34 W37 V228 E264 T265 V266 L271 I272R33-T268 HydrophobicContact CG-CG2 3.92Å; R33-T268 WeakPolarHBondContact CG-OG1 3.37Å; R33-T268 PolarHBondContact NE-OG1 3.36Å; R33-T268 PolarHBondContact NH2-OG1 3.48Å; L34-T268 HydrophobicContact CD2-CG2 4.21Å; W37-T268 HydrophobicContact CD2-CG2 4.24Å; W37-T268 HydrophobicContact CE3-CG2 4.11Å; W37-T268 HydrophobicContact CG-CG2 4.48Å; V228-T268 HydrophobicContact CG1-CG2 4.4Å; V228-T268 HydrophobicContact CG2-CG2 4.15Å; E264-T268 WeakPolarHBondContact O-CB 3.48Å; E264-T268 PolarHBondContact O-N 2.85Å; E264-T268 VanDerWaalsContact O-N 3.11Å; E264-T268 PolarHBondContact O-OG1 2.89Å; T265-T268 WeakPolarHBondContact O-CB 3.29Å; T265-T268 PolarHBondContact O-N 3.04Å; T265-T268 VanDerWaalsContact O-N 3.15Å; V266-T268 PolarHBondContact O-N 3.44Å; T268-L271 PolarHBondContact O-N 2.87Å; T268-I272 HydrophobicContact CG2-CD1 4.13Å; T268-I272 PolarHBondContact O-N 3.09Å; T268-I272 VanDerWaalsContact O-N 3.16Å
269S95.6Very high90.9Very high0 Ų047.5 Ų47.50%026%0.261CS..Hα-helixtrans-57.6-48174.7171.20000112.4N229 T265 V266 L271 I272 S273 I280N229-S269 PolarHBondContact ND2-O 2.96Å; N229-S269 VanDerWaalsContact OD1-CB 3.23Å; N229-S269 WeakPolarHBondContact OD1-CB 3.46Å; N229-S269 PolarHBondContact OD1-OG 3.23Å; T265-S269 WeakPolarHBondContact O-CB 3.34Å; T265-S269 PolarHBondContact O-N 2.84Å; V266-S269 WeakPolarHBondContact O-CB 3.47Å; V266-S269 PolarHBondContact O-N 3.17Å; S269-L271 PolarHBondContact O-N 2.79Å; S269-I272 PolarHBondContact O-N 2.81Å; S269-S273 WeakPolarHBondContact O-CB 3.22Å; S269-S273 PolarHBondContact O-N 3.11Å; S269-I280 WeakPolarHBondContact OG-CD1 2.96Å
270E88.6Confident90.6Very high91 Ų9145 Ų4543%0.42525%0.247SC..Hα-helixtrans-64.5-38.2178.3-73.1-179.8171.900113V266 S273 R274 I280V266-E270 HydrophobicContact CG1-CG 4.25Å; V266-E270 WeakPolarHBondContact O-CG 3.45Å; V266-E270 PolarHBondContact O-N 2.92Å; E270-S273 PolarHBondContact O-N 3.26Å; E270-R274 WeakPolarHBondContact O-CB 3.18Å; E270-R274 PolarHBondContact O-N 3.48Å; E270-I280 HydrophobicContact CG-CD1 4.44Å
271L86.4Confident90.4Very high35 Ų3547.7 Ų47.718%0.18327%0.265CS..Hα-helixtrans-62.1-47.4176.7-177.471.4000110.9R33 N267 T268 S269 R274 F275R33-L271 HydrophobicContact CB-CD2 3.59Å; R33-L271 HydrophobicContact CG-CD2 3.67Å; N267-L271 WeakPolarHBondContact O-CB 3.31Å; N267-L271 PolarHBondContact O-N 3.07Å; T268-L271 PolarHBondContact O-N 2.87Å; S269-L271 PolarHBondContact O-N 2.79Å; L271-R274 PolarHBondContact O-N 3.12Å; L271-F275 HydrophobicContact CD1-CD2 4.1Å; L271-F275 HydrophobicContact CD1-CE1 4.43Å; L271-F275 HydrophobicContact CD1-CE2 3.48Å; L271-F275 VanDerWaalsContact CD1-CE2 3.48Å; L271-F275 HydrophobicContact CD1-CZ 3.67Å; L271-F275 HydrophobicContact CD2-CE2 4.25Å; L271-F275 HydrophobicContact CG-CD2 4.03Å; L271-F275 HydrophobicContact CG-CE2 3.78Å; L271-F275 HydrophobicContact CG-CZ 4.46Å; L271-F275 PolarHBondContact O-N 2.88Å
272I91.2Very high89.9Confident1 Ų151.3 Ų51.31%0.00528%0.276CS..Hα-helixtrans-69.3-39.8-179.3-70.5166.6000110.3T10 I30 L34 V228 I231 T268 S269 R274 F275 S276T10-I272 HydrophobicContact CG2-CD1 4.02Å; T10-I272 HydrophobicContact CG2-CG1 4.39Å; T10-I272 HydrophobicContact CG2-CG2 3.91Å; I30-I272 HydrophobicContact CD1-CG1 4.43Å; I30-I272 HydrophobicContact CG1-CG1 4.18Å; I30-I272 HydrophobicContact CG2-CD1 4.13Å; I30-I272 HydrophobicContact CG2-CG1 4.13Å; L34-I272 HydrophobicContact CD2-CD1 4.4Å; V228-I272 HydrophobicContact CB-CD1 3.45Å; V228-I272 VanDerWaalsContact CB-CD1 3.45Å; V228-I272 HydrophobicContact CG1-CD1 3.81Å; V228-I272 HydrophobicContact CG2-CD1 3.62Å; I231-I272 HydrophobicContact CD1-CG2 4.19Å; T268-I272 HydrophobicContact CG2-CD1 4.13Å; T268-I272 PolarHBondContact O-N 3.09Å; T268-I272 VanDerWaalsContact O-N 3.16Å; S269-I272 PolarHBondContact O-N 2.81Å; I272-R274 VanDerWaalsContact C-N 3.32Å; I272-R274 PolarHBondContact O-N 3.49Å; I272-F275 PolarHBondContact O-N 2.82Å; I272-S276 WeakPolarHBondContact O-CB 3.34Å; I272-S276 PolarHBondContact O-N 2.91Å; I272-S276 PolarHBondContact O-OG 2.72Å
273S89Confident89.7Confident20 Ų2057 Ų5714%0.1431%0.306CS..Hα-helixtrans-56.5-45.9171.9177.20000111.7S269 E270 S276 G277 I278S269-S273 WeakPolarHBondContact O-CB 3.22Å; S269-S273 PolarHBondContact O-N 3.11Å; E270-S273 PolarHBondContact O-N 3.26Å; S273-S276 PolarHBondContact O-OG 2.98Å; S273-G277 PolarHBondContact O-N 3.31Å; S273-I278 WeakPolarHBondContact CA-O 3.43Å; S273-I278 WeakPolarHBondContact CB-O 3.33Å; S273-I278 PolarHBondContact O-N 3.41Å; S273-I278 PolarHBondContact OG-O 3.48Å
274R80.8Confident89.8Confident182 Ų18254.6 Ų54.669%0.68729%0.292SS*.Hα-helixtrans-62.3-47.3178.1-174-174.4-55.8173.64.6112.9E270 L271 I272E270-R274 WeakPolarHBondContact O-CB 3.18Å; E270-R274 PolarHBondContact O-N 3.48Å; L271-R274 PolarHBondContact O-N 3.12Å; I272-R274 VanDerWaalsContact C-N 3.32Å; I272-R274 PolarHBondContact O-N 3.49Å
275F82.5Confident89.8Confident53 Ų5355.6 Ų55.623%0.23231%0.305CS..Hα-helixtrans-77-28.6-177.3-67.9-25.7000113.3F22 E26 A29 I30 L271 I272F22-F275 HydrophobicContact CD1-CB 3.87Å; F22-F275 HydrophobicContact CE1-CB 3.77Å; E26-F275 HydrophobicContact CB-CB 4.47Å; E26-F275 HydrophobicContact CB-CD2 3.93Å; E26-F275 HydrophobicContact CB-CE2 4.2Å; E26-F275 HydrophobicContact CB-CG 4.1Å; E26-F275 HydrophobicContact CG-CB 4.44Å; E26-F275 HydrophobicContact CG-CD1 3.8Å; E26-F275 HydrophobicContact CG-CD2 4.05Å; E26-F275 HydrophobicContact CG-CE1 3.95Å; E26-F275 HydrophobicContact CG-CE2 4.17Å; E26-F275 HydrophobicContact CG-CG 3.87Å; E26-F275 HydrophobicContact CG-CZ 4.12Å; A29-F275 HydrophobicContact CB-CE2 3.97Å; A29-F275 HydrophobicContact CB-CZ 4.44Å; I30-F275 HydrophobicContact CD1-CB 4.41Å; I30-F275 HydrophobicContact CD1-CD2 3.94Å; I30-F275 HydrophobicContact CG1-CD2 3.75Å; I30-F275 HydrophobicContact CG1-CE2 4.29Å; L271-F275 HydrophobicContact CD1-CD2 4.1Å; L271-F275 HydrophobicContact CD1-CE1 4.43Å; L271-F275 HydrophobicContact CD1-CE2 3.48Å; L271-F275 VanDerWaalsContact CD1-CE2 3.48Å; L271-F275 HydrophobicContact CD1-CZ 3.67Å; L271-F275 HydrophobicContact CD2-CE2 4.25Å; L271-F275 HydrophobicContact CG-CD2 4.03Å; L271-F275 HydrophobicContact CG-CE2 3.78Å; L271-F275 HydrophobicContact CG-CZ 4.46Å; L271-F275 PolarHBondContact O-N 2.88Å; I272-F275 PolarHBondContact O-N 2.82Å
276S86.6Confident89.8Confident9 Ų956 Ų566%0.06331%0.308CS..Hα-helixtrans-80.5-21.2176.560.10000112.5I272 S273 I278I272-S276 WeakPolarHBondContact O-CB 3.34Å; I272-S276 PolarHBondContact O-N 2.91Å; I272-S276 PolarHBondContact O-OG 2.72Å; S273-S276 PolarHBondContact O-OG 2.98Å; S276-I278 PolarHBondContact O-N 3.1Å; S276-I278 PolarHBondContact OG-N 3.02Å
277G81.3Confident89.8Confident64 Ų6456.1 Ų56.166%0.6631%0.308SS*.  trans744.1-170.500000113.5S273S273-G277 PolarHBondContact O-N 3.31Å
278I87.4Confident90Very high61 Ų6153.1 Ų53.131%0.31329%0.292SS..PPolyproline II helixtrans-92.2116.2179.8-60176.9000108.8T17 V20 I231 S273 S276T17-I278 HydrophobicContact CG2-CD1 3.52Å; V20-I278 HydrophobicContact CG2-CD1 3.55Å; V20-I278 HydrophobicContact CG2-CG1 4.15Å; I231-I278 HydrophobicContact CG2-CD1 3.89Å; S273-I278 WeakPolarHBondContact CA-O 3.43Å; S273-I278 WeakPolarHBondContact CB-O 3.33Å; S273-I278 PolarHBondContact O-N 3.41Å; S273-I278 PolarHBondContact OG-O 3.48Å; S276-I278 PolarHBondContact O-N 3.1Å; S276-I278 PolarHBondContact OG-N 3.02Å
279S88.7Confident89.5Confident100 Ų10055.8 Ų55.870%0.69932%0.32SS*.PPolyproline II helixtrans-69.2140.9177.7-66.80000111.6P281S279-P281 WeakPolarHBondContact O-CD 3.48Å
280I90.7Very high89.1Confident43 Ų4360.1 Ų60.122%0.22134%0.343CS..PPolyproline II helixtrans-76121.2173.5-60.5157.9000108.4S269 E270 K282 K284 V287S269-I280 WeakPolarHBondContact OG-CD1 2.96Å; E270-I280 HydrophobicContact CG-CD1 4.44Å; I280-K282 PolarHBondContact O-N 2.92Å; I280-K284 HydrophobicContact CG2-CB 4.01Å; I280-K284 HydrophobicContact CG2-CG 4.37Å; I280-V287 HydrophobicContact CG2-CG2 3.93Å
281P93.3Very high89Confident70 Ų7058 Ų5846%0.45534%0.341SS..PPolyproline II helixtrans-57.3136.4174.4-24.333.9000111S279 N283 K284 G288S279-P281 WeakPolarHBondContact O-CD 3.48Å; P281-N283 PolarHBondContact O-N 3.4Å; P281-K284 HydrophobicContact CB-CB 4.29Å; P281-K284 VanDerWaalsContact O-CB 3.27Å; P281-K284 WeakPolarHBondContact O-CB 3.4Å; P281-K284 PolarHBondContact O-N 3.5Å; P281-G288 WeakPolarHBondContact O-CA 3.49Å
282K88.6Confident88.8Confident145 Ų14557.2 Ų57.263%0.6334%0.336SS*.THydrogen-bonded Turntrans-55.5-30.1-179.9-67.4-171.7178.3-174.30112.4I280 G288 G289 N290I280-K282 PolarHBondContact O-N 2.92Å; K282-G288 CarbonylContact O-C 3.51Å; K282-G288 VanDerWaalsContact O-CA 3.29Å; K282-G288 WeakPolarHBondContact O-CA 3.27Å; K282-G289 PolarHBondContact O-N 3.11Å; K282-G289 VanDerWaalsContact O-N 3.13Å; K282-N290 WeakPolarHBondContact O-CA 3.45Å; K282-N290 VanDerWaalsContact O-CB 3.28Å; K282-N290 WeakPolarHBondContact O-CB 3.07Å; K282-N290 PolarHBondContact O-N 2.79Å
283N93.1Very high88.3Confident133 Ų13358.6 Ų58.671%0.71135%0.346SS*.THydrogen-bonded Turntrans-98.812.7179.463.8-30.1000114.2P281 A285P281-N283 PolarHBondContact O-N 3.4Å; N283-A285 PolarHBondContact O-N 3.17Å
284K95.7Very high87.9Confident34 Ų3458.9 Ų58.915%0.14835%0.345CS..  trans-60.9134.6173.2-175.760.3164.7680109.5A239 E241 E242 I280 P281 V287 G288A239-K284 VanDerWaalsContact CB-NZ 3.29Å; E241-K284 IonicContact OE1-NZ 2.7Å; E241-K284 PolarHBondContact OE1-NZ 3.24Å; E242-K284 IonicContact OE1-NZ 3.01Å; E242-K284 PolarHBondContact OE1-NZ 3.26Å; I280-K284 HydrophobicContact CG2-CB 4.01Å; I280-K284 HydrophobicContact CG2-CG 4.37Å; P281-K284 HydrophobicContact CB-CB 4.29Å; P281-K284 VanDerWaalsContact O-CB 3.27Å; P281-K284 WeakPolarHBondContact O-CB 3.4Å; P281-K284 PolarHBondContact O-N 3.5Å; K284-V287 HydrophobicContact CB-CG2 4.37Å; K284-V287 HydrophobicContact CG-CG2 3.76Å; K284-G288 VanDerWaalsContact O-CA 3.27Å; K284-G288 WeakPolarHBondContact O-CA 3.19Å; K284-G288 PolarHBondContact O-N 2.79Å
285A95.7Very high87.7Confident51 Ų5154.3 Ų54.342%0.42133%0.331SS..THydrogen-bonded Turntrans-58.8146176.100000110.5E242 N283 V287E242-A285 HydrophobicContact CG-CB 4.12Å; N283-A285 PolarHBondContact O-N 3.17Å; A285-V287 PolarHBondContact O-N 3.04Å
286V95.7Very high87.6Confident10 Ų1053.3 Ų53.36%0.06133%0.331CS..THydrogen-bonded Turntrans68.3-49.1179.2-177.20000115.6E241 E242 V245 T265 F292 I313 V318E241-V286 HydrophobicContact CB-CG1 4.37Å; E241-V286 HydrophobicContact CG-CB 4.33Å; E241-V286 HydrophobicContact CG-CG1 4.45Å; E242-V286 HydrophobicContact CG-CG2 4.42Å; V245-V286 HydrophobicContact CB-CG1 4.33Å; V245-V286 HydrophobicContact CB-CG2 3.83Å; V245-V286 HydrophobicContact CG1-CG2 4.08Å; V245-V286 HydrophobicContact CG2-CB 4.47Å; V245-V286 HydrophobicContact CG2-CG1 3.56Å; V245-V286 HydrophobicContact CG2-CG2 4.01Å; T265-V286 HydrophobicContact CG2-CG1 4.06Å; V286-F292 WeakPolarHBondContact O-CE2 3.41Å; V286-F292 WeakPolarHBondContact O-CZ 3.1Å; V286-I313 HydrophobicContact CG2-CD1 4.44Å; V286-V318 HydrophobicContact CG1-CB 4.47Å; V286-V318 HydrophobicContact CG1-CG1 3.87Å
287V94.2Very high87.2Confident14 Ų1453.3 Ų53.39%0.08533%0.333CS..THydrogen-bonded Turntrans-114.2-8.3-168.6-64.50000114.2E241 T265 V266 I280 K284 A285E241-V287 HydrophobicContact CB-CG1 4.37Å; E241-V287 HydrophobicContact CG-CG1 3.97Å; E241-V287 HydrophobicContact CG-CG2 4.29Å; T265-V287 HydrophobicContact CG2-CG1 3.94Å; V266-V287 HydrophobicContact CG2-CG1 4.22Å; I280-V287 HydrophobicContact CG2-CG2 3.93Å; K284-V287 HydrophobicContact CB-CG2 4.37Å; K284-V287 HydrophobicContact CG-CG2 3.76Å; A285-V287 PolarHBondContact O-N 3.04Å
288G91.5Very high87.3Confident0 Ų056.4 Ų56.40%033%0.332CS..SBendtrans-68.7140.5176.900000111.8P281 K282 K284 N290 A291P281-G288 WeakPolarHBondContact O-CA 3.49Å; K282-G288 CarbonylContact O-C 3.51Å; K282-G288 VanDerWaalsContact O-CA 3.29Å; K282-G288 WeakPolarHBondContact O-CA 3.27Å; K284-G288 VanDerWaalsContact O-CA 3.27Å; K284-G288 WeakPolarHBondContact O-CA 3.19Å; K284-G288 PolarHBondContact O-N 2.79Å; G288-N290 PolarHBondContact O-N 2.86Å; G288-A291 WeakPolarHBondContact O-CB 3.48Å; G288-A291 PolarHBondContact O-N 3.32Å
289G83.6Confident87.1Confident56 Ų5656.8 Ų56.858%0.57733%0.333SS*.THydrogen-bonded Turntrans-57.1-24.9-179.500000114.9K282 S293K282-G289 PolarHBondContact O-N 3.11Å; K282-G289 VanDerWaalsContact O-N 3.13Å; G289-S293 PolarHBondContact O-OG 2.84Å
290N86.5Confident86.8Confident90 Ų9052 Ų5248%0.48130%0.3SS..THydrogen-bonded Turntrans-89.9-5.3176.1-63.4-6.8000113.4K282 G288 F292 S293K282-N290 WeakPolarHBondContact O-CA 3.45Å; K282-N290 VanDerWaalsContact O-CB 3.28Å; K282-N290 WeakPolarHBondContact O-CB 3.07Å; K282-N290 PolarHBondContact O-N 2.79Å; G288-N290 PolarHBondContact O-N 2.86Å; N290-F292 PolarHBondContact O-N 2.64Å; N290-F292 VanDerWaalsContact O-N 3.13Å; N290-S293 PolarHBondContact O-N 3.12Å; N290-S293 VanDerWaalsContact O-N 3.16Å
291A86.3Confident86.5Confident46 Ų4652.2 Ų52.238%0.3830%0.301SS..THydrogen-bonded Turntrans-61.6-22.3-177.900000112.9G288G288-A291 WeakPolarHBondContact O-CB 3.48Å; G288-A291 PolarHBondContact O-N 3.32Å
292F83.1Confident86.1Confident19 Ų1949.4 Ų49.48%0.08329%0.285CS..THydrogen-bonded Turntrans-116.48-179.4-49.4-69.3000113.2V286 N290 I313 P315 V318 V320V286-F292 WeakPolarHBondContact O-CE2 3.41Å; V286-F292 WeakPolarHBondContact O-CZ 3.1Å; N290-F292 PolarHBondContact O-N 2.64Å; N290-F292 VanDerWaalsContact O-N 3.13Å; F292-I313 HydrophobicContact CE1-CB 4.1Å; F292-I313 HydrophobicContact CE1-CG2 3.7Å; F292-I313 HydrophobicContact CZ-CG2 4.2Å; F292-P315 HydrophobicContact CB-CG 4.05Å; F292-P315 HydrophobicContact CD1-CB 4.36Å; F292-P315 HydrophobicContact CD1-CG 4.07Å; F292-P315 HydrophobicContact CG-CB 4.23Å; F292-P315 HydrophobicContact CG-CG 4.04Å; F292-V318 HydrophobicContact CE1-CG2 4.25Å; F292-V318 HydrophobicContact CE2-CG2 3.96Å; F292-V318 HydrophobicContact CZ-CG2 3.42Å; F292-V318 VanDerWaalsContact CZ-CG2 3.42Å; F292-V320 HydrophobicContact CD2-CG2 4.2Å; F292-V320 HydrophobicContact CE2-CG2 3.89Å
293S80.5Confident85.9Confident30 Ų3043.2 Ų43.221%0.2126%0.259CS..  trans-101138.3-174.8-71.70000111.7G289 N290G289-S293 PolarHBondContact O-OG 2.84Å; N290-S293 PolarHBondContact O-N 3.12Å; N290-S293 VanDerWaalsContact O-N 3.16Å
294H79.6Confident85.4Confident27 Ų2740 Ų4013%0.12524%0.241CC..  trans-124.8110.3176.4-58.2-65000111H299 Q300 E311H294-H299 HydrophobicContact CB-CB 4.2Å; H294-Q300 HydrophobicContact CB-CG 4.07Å; H294-Q300 VanDerWaalsContact O-CD 3.24Å; H294-Q300 WeakPolarHBondContact O-CG 3.39Å; H294-Q300 PolarHBondContact O-NE2 3.15Å; H294-E311 IonicContact NE2-OE1 2.75Å
295E76.6Confident85Confident85 Ų8545.2 Ų45.240%0.39726%0.264SS..  trans-86.5-34.2176.5-162-165.2155.100112.3G297 G328 K329 L330 S331E295-G297 PolarHBondContact O-N 3.29Å; E295-G328 WeakPolarHBondContact OE1-CA 3.47Å; E295-K329 PolarHBondContact OE1-N 3.45Å; E295-L330 HydrophobicContact CG-CB 4.22Å; E295-L330 CarbonylContact O-C 3.2Å; E295-L330 PolarHBondContact OE1-N 2.89Å; E295-S331 WeakPolarHBondContact O-CA 3.37Å; E295-S331 PolarHBondContact O-N 2.85Å; E295-S331 VanDerWaalsContact O-N 3.1Å; E295-S331 PolarHBondContact O-OG 3.14Å; E295-S331 VanDerWaalsContact O-OG 3.07Å
296S80.7Confident84.6Confident32 Ų3246.5 Ų46.522%0.22426%0.264CS..SBendtrans-63.9123.8-178.6172.60000111I298 H299 Q300S296-I298 PolarHBondContact O-N 2.86Å; S296-H299 WeakPolarHBondContact O-CA 3.19Å; S296-H299 WeakPolarHBondContact O-CB 3.32Å; S296-H299 PolarHBondContact O-N 2.88Å; S296-Q300 WeakPolarHBondContact O-CG 3.37Å; S296-Q300 PolarHBondContact O-N 2.72Å
297G78.5Confident84Confident10 Ų1049 Ų4910%0.10328%0.28CS..Hα-helixtrans-58.4-31.4179.200000114.8E295 H299 D301 L330 G332E295-G297 PolarHBondContact O-N 3.29Å; G297-H299 VanDerWaalsContact C-N 3.33Å; G297-D301 VanDerWaalsContact O-CB 3.31Å; G297-D301 WeakPolarHBondContact O-CB 3.44Å; G297-D301 PolarHBondContact O-N 3.36Å; G297-L330 PolarHBondContact N-O 2.88Å; G297-G332 VanDerWaalsContact CA-CA 3.48Å
298I83.1Confident83.6Confident128 Ų12854.6 Ų54.666%0.65631%0.309SS*.Hα-helixtrans-68.6-38174.4-62171.6000109.9S296 G302S296-I298 PolarHBondContact O-N 2.86Å; I298-G302 PolarHBondContact O-N 2.77Å; I298-G302 VanDerWaalsContact O-N 3.09Å
299H83.9Confident83.4Confident70 Ų7058 Ų5832%0.32433%0.33SS..Hα-helixtrans-73.3-44.2179.4-63.3-168.5000111H294 S296 G297 D301 G302 V303 Y310H294-H299 HydrophobicContact CB-CB 4.2Å; S296-H299 WeakPolarHBondContact O-CA 3.19Å; S296-H299 WeakPolarHBondContact O-CB 3.32Å; S296-H299 PolarHBondContact O-N 2.88Å; G297-H299 VanDerWaalsContact C-N 3.33Å; H299-D301 VanDerWaalsContact C-N 3.33Å; H299-D301 PolarHBondContact O-N 3Å; H299-G302 WeakPolarHBondContact O-CA 3.41Å; H299-G302 PolarHBondContact O-N 3.36Å; H299-G302 VanDerWaalsContact O-N 3.1Å; H299-V303 WeakPolarHBondContact O-CG2 3.24Å; H299-V303 PolarHBondContact O-N 3.2Å; H299-Y310 VanDerWaalsContact CA-CE2 3.46Å; H299-Y310 HydrophobicContact CB-CD1 4.36Å; H299-Y310 HydrophobicContact CB-CD2 4.08Å; H299-Y310 HydrophobicContact CB-CE1 4.21Å; H299-Y310 HydrophobicContact CB-CE2 3.95Å; H299-Y310 HydrophobicContact CB-CG 4.3Å; H299-Y310 AromaticContact CD2-CE1 3.37Å; H299-Y310 WeakPolarHBondContact CD2-CE1 3.31Å; H299-Y310 AromaticContact CD2-CZ 3.28Å; H299-Y310 PolarHBondContact CD2-OH 3.13Å; H299-Y310 AromaticContact CE1-CE1 3.7Å; H299-Y310 AromaticContact CG-CD1 3.95Å; H299-Y310 AromaticContact CG-CE1 3.53Å; H299-Y310 AromaticContact CG-CZ 3.61Å; H299-Y310 AromaticContact ND1-CD1 3.91Å; H299-Y310 AromaticContact ND1-CE1 3.73Å; H299-Y310 AromaticContact NE2-CE1 3.52Å; H299-Y310 AromaticContact NE2-CZ 3.86Å
300Q81.5Confident83.5Confident0 Ų059.6 Ų59.60%032%0.319CS..Hα-helixtrans-58.2-45.7175.2-65.9172.4-43.700111H294 S296 G302 V303 L304 L325 P326 S331 A335H294-Q300 HydrophobicContact CB-CG 4.07Å; H294-Q300 VanDerWaalsContact O-CD 3.24Å; H294-Q300 WeakPolarHBondContact O-CG 3.39Å; H294-Q300 PolarHBondContact O-NE2 3.15Å; S296-Q300 WeakPolarHBondContact O-CG 3.37Å; S296-Q300 PolarHBondContact O-N 2.72Å; Q300-G302 VanDerWaalsContact C-N 3.3Å; Q300-G302 PolarHBondContact O-N 2.56Å; Q300-V303 PolarHBondContact O-N 2.84Å; Q300-L304 VanDerWaalsContact O-CB 3.29Å; Q300-L304 WeakPolarHBondContact O-CB 3.49Å; Q300-L304 WeakPolarHBondContact O-CD1 3.31Å; Q300-L304 WeakPolarHBondContact O-CG 3.35Å; Q300-L304 PolarHBondContact O-N 3.04Å; Q300-L325 HydrophobicContact CB-CD1 4.46Å; Q300-L325 HydrophobicContact CG-CD1 4.07Å; Q300-P326 PolarHBondContact NE2-O 3.35Å; Q300-S331 PolarHBondContact NE2-OG 2.58Å; Q300-S331 VanDerWaalsContact OE1-CB 3.24Å; Q300-S331 PolarHBondContact OE1-OG 3.16Å; Q300-A335 HydrophobicContact CB-CB 3.51Å; Q300-A335 HydrophobicContact CG-CB 3.93Å
301D84.1Confident83.6Confident47 Ų4756.1 Ų56.125%0.25130%0.3SS..Hα-helixtrans-60.3-38.9175176.878.3000112.7G297 H299 K305 H334G297-D301 VanDerWaalsContact O-CB 3.31Å; G297-D301 WeakPolarHBondContact O-CB 3.44Å; G297-D301 PolarHBondContact O-N 3.36Å; H299-D301 VanDerWaalsContact C-N 3.33Å; H299-D301 PolarHBondContact O-N 3Å; D301-K305 WeakPolarHBondContact O-CD 3.28Å; D301-K305 VanDerWaalsContact O-CG 3.26Å; D301-K305 WeakPolarHBondContact O-CG 3.29Å; D301-K305 PolarHBondContact O-N 3.27Å; D301-K305 WeakPolarHBondContact OD1-CE 3.43Å; D301-K305 IonicContact OD1-NZ 3.04Å; D301-K305 PolarHBondContact OD1-NZ 3.45Å; D301-K305 WeakPolarHBondContact OD2-CE 3.3Å; D301-K305 IonicContact OD2-NZ 2.64Å; D301-K305 PolarHBondContact OD2-NZ 3.46Å; D301-H334 HydrophobicContact CB-CB 4.44Å; D301-H334 IonicContact OD1-CD2 3.34Å; D301-H334 PolarHBondContact OD1-CD2 2.94Å; D301-H334 IonicContact OD1-CG 3.68Å
302G86Confident83.7Confident11 Ų1159.9 Ų59.911%0.11331%0.312CS..Hα-helixtrans-61.7-51.9172.300000112.7I298 H299 Q300 L304 K305 N306 T309I298-G302 PolarHBondContact O-N 2.77Å; I298-G302 VanDerWaalsContact O-N 3.09Å; H299-G302 WeakPolarHBondContact O-CA 3.41Å; H299-G302 PolarHBondContact O-N 3.36Å; H299-G302 VanDerWaalsContact O-N 3.1Å; Q300-G302 VanDerWaalsContact C-N 3.3Å; Q300-G302 PolarHBondContact O-N 2.56Å; G302-L304 PolarHBondContact O-N 2.86Å; G302-K305 PolarHBondContact O-N 3.39Å; G302-N306 CarbonylContact O-C 3.33Å; G302-N306 PolarHBondContact O-N 3.48Å; G302-T309 PolarHBondContact O-OG1 3.44Å; G302-T309 VanDerWaalsContact O-OG1 3.11Å
303V84.4Confident84.1Confident14 Ų1460.3 Ų60.39%0.08532%0.315CS..Hα-helixtrans-63.4-42.9-178.1169.20000111.9H299 Q300 K305 N306 P307 T309 Y310 E311H299-V303 WeakPolarHBondContact O-CG2 3.24Å; H299-V303 PolarHBondContact O-N 3.2Å; Q300-V303 PolarHBondContact O-N 2.84Å; V303-K305 VanDerWaalsContact C-N 3.25Å; V303-K305 PolarHBondContact O-N 2.97Å; V303-N306 CarbonylContact O-C 3.57Å; V303-N306 PolarHBondContact O-N 3.42Å; V303-P307 HydrophobicContact CG1-CB 4.4Å; V303-P307 VanDerWaalsContact O-CD 3.24Å; V303-P307 WeakPolarHBondContact O-CD 3.5Å; V303-T309 PolarHBondContact N-OG1 3.4Å; V303-Y310 HydrophobicContact CG2-CD2 3.89Å; V303-Y310 HydrophobicContact CG2-CG 4.32Å; V303-E311 VanDerWaalsContact CG1-OE1 3.31Å; V303-E311 WeakPolarHBondContact CG1-OE1 3.12Å; V303-E311 HydrophobicContact CG2-CG 4.41Å
304L82.3Confident84.4Confident66 Ų6661.6 Ų61.635%0.34632%0.322SS..Hα-helixtrans-61.6-33.4176.6-71.8165.6000112.4Q300 G302 E338Q300-L304 VanDerWaalsContact O-CB 3.29Å; Q300-L304 WeakPolarHBondContact O-CB 3.49Å; Q300-L304 WeakPolarHBondContact O-CD1 3.31Å; Q300-L304 WeakPolarHBondContact O-CG 3.35Å; Q300-L304 PolarHBondContact O-N 3.04Å; G302-L304 PolarHBondContact O-N 2.86Å; L304-E338 HydrophobicContact CD1-CB 4.02Å; L304-E338 HydrophobicContact CD1-CG 3.57Å; L304-E338 HydrophobicContact CD2-CB 4.18Å; L304-E338 HydrophobicContact CD2-CG 3.92Å; L304-E338 HydrophobicContact CG-CG 4.3Å
305K88Confident84.7Confident144 Ų14460.3 Ų60.363%0.62632%0.316SS*.Hα-helixtrans-78.2-42.9174.7-72.6168.9-176.5166.60112.5D301 G302 V303D301-K305 WeakPolarHBondContact O-CD 3.28Å; D301-K305 VanDerWaalsContact O-CG 3.26Å; D301-K305 WeakPolarHBondContact O-CG 3.29Å; D301-K305 PolarHBondContact O-N 3.27Å; D301-K305 WeakPolarHBondContact OD1-CE 3.43Å; D301-K305 IonicContact OD1-NZ 3.04Å; D301-K305 PolarHBondContact OD1-NZ 3.45Å; D301-K305 WeakPolarHBondContact OD2-CE 3.3Å; D301-K305 IonicContact OD2-NZ 2.64Å; D301-K305 PolarHBondContact OD2-NZ 3.46Å; G302-K305 PolarHBondContact O-N 3.39Å; V303-K305 VanDerWaalsContact C-N 3.25Å; V303-K305 PolarHBondContact O-N 2.97Å
306N86.1Confident85.3Confident78 Ų7861 Ų6142%0.41732%0.319SS..  trans-159.7111.5176-176.1-12000109.4G302 V303 L308 T309G302-N306 CarbonylContact O-C 3.33Å; G302-N306 PolarHBondContact O-N 3.48Å; V303-N306 CarbonylContact O-C 3.57Å; V303-N306 PolarHBondContact O-N 3.42Å; N306-L308 PolarHBondContact O-N 3.31Å; N306-L308 VanDerWaalsContact O-N 3.08Å; N306-L308 WeakPolarHBondContact OD1-CB 3.44Å; N306-L308 PolarHBondContact OD1-N 3.47Å; N306-L308 VanDerWaalsContact OD1-N 3.15Å; N306-T309 HydrophobicContact CB-CG2 4.2Å; N306-T309 WeakPolarHBondContact O-CB 3.37Å; N306-T309 VanDerWaalsContact O-CG2 3.29Å; N306-T309 WeakPolarHBondContact O-CG2 3.47Å; N306-T309 PolarHBondContact O-N 2.89Å; N306-T309 PolarHBondContact O-OG1 2.98Å
307P84Confident85.9Confident61 Ų6161.8 Ų61.840%0.39632%0.32SS..G310 helixtrans-53.2-34.1-178.4-29.736.1000114V303 T309 Y310 E311V303-P307 HydrophobicContact CG1-CB 4.4Å; V303-P307 VanDerWaalsContact O-CD 3.24Å; V303-P307 WeakPolarHBondContact O-CD 3.5Å; P307-T309 PolarHBondContact O-N 3.48Å; P307-Y310 PolarHBondContact O-N 2.96Å; P307-Y310 VanDerWaalsContact O-N 3.11Å; P307-E311 WeakPolarHBondContact CB-OE2 3.47Å; P307-E311 WeakPolarHBondContact O-CB 3.29Å; P307-E311 PolarHBondContact O-N 3.35Å
308L85.5Confident86.6Confident132 Ų13261.3 Ų61.369%0.69132%0.316SS*.G310 helixtrans-62.5-8.5179.6-61.5177.1000114.8N306 Y310N306-L308 PolarHBondContact O-N 3.31Å; N306-L308 VanDerWaalsContact O-N 3.08Å; N306-L308 WeakPolarHBondContact OD1-CB 3.44Å; N306-L308 PolarHBondContact OD1-N 3.47Å; N306-L308 VanDerWaalsContact OD1-N 3.15Å; L308-Y310 VanDerWaalsContact C-N 3.27Å; L308-Y310 PolarHBondContact O-N 3.38Å
309T87.3Confident86.9Confident71 Ų7155.5 Ų55.544%0.43629%0.287SS..G310 helixtrans-66.4-28.5173.253.60000112.9G302 V303 N306 P307G302-T309 PolarHBondContact O-OG1 3.44Å; G302-T309 VanDerWaalsContact O-OG1 3.11Å; V303-T309 PolarHBondContact N-OG1 3.4Å; N306-T309 HydrophobicContact CB-CG2 4.2Å; N306-T309 WeakPolarHBondContact O-CB 3.37Å; N306-T309 VanDerWaalsContact O-CG2 3.29Å; N306-T309 WeakPolarHBondContact O-CG2 3.47Å; N306-T309 PolarHBondContact O-N 2.89Å; N306-T309 PolarHBondContact O-OG1 2.98Å; P307-T309 PolarHBondContact O-N 3.48Å
310Y86.2Confident86.9Confident91 Ų9153.9 Ų53.936%0.35728%0.283SS..THydrogen-bonded Turntrans-138.2-22.4179.4-65.3-81.9000113.9H299 V303 P307 L308 I312H299-Y310 VanDerWaalsContact CA-CE2 3.46Å; H299-Y310 HydrophobicContact CB-CD1 4.36Å; H299-Y310 HydrophobicContact CB-CD2 4.08Å; H299-Y310 HydrophobicContact CB-CE1 4.21Å; H299-Y310 HydrophobicContact CB-CE2 3.95Å; H299-Y310 HydrophobicContact CB-CG 4.3Å; H299-Y310 AromaticContact CD2-CE1 3.37Å; H299-Y310 WeakPolarHBondContact CD2-CE1 3.31Å; H299-Y310 AromaticContact CD2-CZ 3.28Å; H299-Y310 PolarHBondContact CD2-OH 3.13Å; H299-Y310 AromaticContact CE1-CE1 3.7Å; H299-Y310 AromaticContact CG-CD1 3.95Å; H299-Y310 AromaticContact CG-CE1 3.53Å; H299-Y310 AromaticContact CG-CZ 3.61Å; H299-Y310 AromaticContact ND1-CD1 3.91Å; H299-Y310 AromaticContact ND1-CE1 3.73Å; H299-Y310 AromaticContact NE2-CE1 3.52Å; H299-Y310 AromaticContact NE2-CZ 3.86Å; V303-Y310 HydrophobicContact CG2-CD2 3.89Å; V303-Y310 HydrophobicContact CG2-CG 4.32Å; P307-Y310 PolarHBondContact O-N 2.96Å; P307-Y310 VanDerWaalsContact O-N 3.11Å; L308-Y310 VanDerWaalsContact C-N 3.27Å; L308-Y310 PolarHBondContact O-N 3.38Å; Y310-I312 PolarHBondContact O-N 2.96Å
311E87Confident86.2Confident16 Ų1662.4 Ų62.48%0.07532%0.32CS..  trans-93.897-178.4-61-180-174.100111H294 V303 P307 I313H294-E311 IonicContact NE2-OE1 2.75Å; V303-E311 VanDerWaalsContact CG1-OE1 3.31Å; V303-E311 WeakPolarHBondContact CG1-OE1 3.12Å; V303-E311 HydrophobicContact CG2-CG 4.41Å; P307-E311 WeakPolarHBondContact CB-OE2 3.47Å; P307-E311 WeakPolarHBondContact O-CB 3.29Å; P307-E311 PolarHBondContact O-N 3.35Å; E311-I313 VanDerWaalsContact C-N 3.32Å
312I89.9Confident85Confident125 Ų12568 Ų6864%0.64134%0.344SS*.SBendtrans-81.1-16168.557.3158.6000112.7I249 Y310I249-I312 WeakPolarHBondContact CD1-O 3.28Å; I249-I312 HydrophobicContact CG2-CB 4.44Å; I249-I312 HydrophobicContact CG2-CD1 4.44Å; Y310-I312 PolarHBondContact O-N 2.96Å
313I90.5Very high83.5Confident29 Ų2971.3 Ų71.315%0.14936%0.359CS..SBendtrans-129.7116178.1-58.6157.4000105.1V245 I249 V286 F292 E311 L317 V318V245-I313 HydrophobicContact CG1-CD1 3.53Å; V245-I313 HydrophobicContact CG1-CG1 3.61Å; V245-I313 HydrophobicContact CG1-CG2 4.31Å; I249-I313 HydrophobicContact CD1-CG1 4.34Å; I249-I313 HydrophobicContact CG1-CG1 4.02Å; V286-I313 HydrophobicContact CG2-CD1 4.44Å; F292-I313 HydrophobicContact CE1-CB 4.1Å; F292-I313 HydrophobicContact CE1-CG2 3.7Å; F292-I313 HydrophobicContact CZ-CG2 4.2Å; E311-I313 VanDerWaalsContact C-N 3.32Å; I313-L317 HydrophobicContact CG2-CD2 4.21Å; I313-V318 HydrophobicContact CG2-CG1 3.63Å
314T87.5Confident82.3Confident57 Ų5774.2 Ų74.235%0.3538%0.38SS..  trans-76.3147.4172.972.70000109.5E316 L317T314-E316 WeakPolarHBondContact CB-OE2 3.14Å; T314-E316 PolarHBondContact O-N 3Å; T314-E316 PolarHBondContact OG1-OE2 3.16Å; T314-L317 VanDerWaalsContact O-CB 3.24Å; T314-L317 WeakPolarHBondContact O-CB 3.4Å; T314-L317 PolarHBondContact O-N 3.06Å; T314-L317 PolarHBondContact OG1-N 3.36Å
315P86.6Confident81.7Confident0 Ų072.3 Ų72.30%037%0.37CS..Hα-helixtrans-53.9-39.6176.8-18.224.1000112.4F292 L317 V318 G319 V320 N323F292-P315 HydrophobicContact CB-CG 4.05Å; F292-P315 HydrophobicContact CD1-CB 4.36Å; F292-P315 HydrophobicContact CD1-CG 4.07Å; F292-P315 HydrophobicContact CG-CB 4.23Å; F292-P315 HydrophobicContact CG-CG 4.04Å; P315-L317 VanDerWaalsContact C-N 3.28Å; P315-L317 PolarHBondContact O-N 3.01Å; P315-V318 VanDerWaalsContact O-CG2 3.32Å; P315-V318 WeakPolarHBondContact O-CG2 3.4Å; P315-V318 PolarHBondContact O-N 2.82Å; P315-G319 PolarHBondContact O-N 3.18Å; P315-V320 HydrophobicContact CB-CB 3.61Å; P315-V320 HydrophobicContact CB-CG1 3.93Å; P315-V320 HydrophobicContact CB-CG2 4.34Å; P315-V320 WeakPolarHBondContact O-CB 3.33Å; P315-V320 PolarHBondContact O-N 3.14Å; P315-N323 HydrophobicContact CG-CB 4.35Å; P315-N323 VanDerWaalsContact CG-CG 3.5Å; P315-N323 WeakPolarHBondContact CG-OD1 3.13Å
316E89.1Confident80.8Confident98 Ų9867.7 Ų67.746%0.45836%0.355SS..Hα-helixtrans-68.1-28.2-179-57.674-161.200112.5N263 T314 V318 G319N263-E316 PolarHBondContact ND2-O 3.35Å; T314-E316 WeakPolarHBondContact CB-OE2 3.14Å; T314-E316 PolarHBondContact O-N 3Å; T314-E316 PolarHBondContact OG1-OE2 3.16Å; E316-V318 PolarHBondContact O-N 3.12Å; E316-G319 PolarHBondContact O-N 3.44Å
317L92.7Very high80.3Confident49 Ų4964.4 Ų64.426%0.25734%0.337SS..Hα-helixtrans-58.9-38.3177.3-179.261.6000110.5I249 L262 N263 I313 T314 P315I249-L317 HydrophobicContact CD1-CD2 3.78Å; L262-L317 CarbonylContact C-O 3.51Å; L262-L317 HydrophobicContact CB-CD1 4.3Å; L262-L317 HydrophobicContact CB-CG 4.43Å; L262-L317 VanDerWaalsContact CB-O 3.23Å; L262-L317 WeakPolarHBondContact CB-O 3.23Å; L262-L317 HydrophobicContact CD1-CD1 3.81Å; L262-L317 HydrophobicContact CD1-CD2 4.33Å; L262-L317 HydrophobicContact CD1-CG 4.02Å; N263-L317 WeakPolarHBondContact CA-O 3.43Å; N263-L317 PolarHBondContact N-O 3.2Å; I313-L317 HydrophobicContact CG2-CD2 4.21Å; T314-L317 VanDerWaalsContact O-CB 3.24Å; T314-L317 WeakPolarHBondContact O-CB 3.4Å; T314-L317 PolarHBondContact O-N 3.06Å; T314-L317 PolarHBondContact OG1-N 3.36Å; P315-L317 VanDerWaalsContact C-N 3.28Å; P315-L317 PolarHBondContact O-N 3.01Å
318V93.6Very high80.1Confident0 Ų061.7 Ų61.70%032%0.32CS..Hα-helixtrans-101.3-1.7-176-59.20000113.7V245 L262 V266 V286 F292 I313 P315 E316 V320V245-V318 HydrophobicContact CG2-CG1 3.89Å; L262-V318 CarbonylContact O-C 3.53Å; L262-V318 VanDerWaalsContact O-CA 3.26Å; L262-V318 WeakPolarHBondContact O-CA 3.41Å; V266-V318 HydrophobicContact CG2-CB 4.16Å; V266-V318 HydrophobicContact CG2-CG2 3.79Å; V266-V318 WeakPolarHBondContact CG2-O 3.45Å; V266-V318 PolarHBondContact N-O 3.19Å; V286-V318 HydrophobicContact CG1-CB 4.47Å; V286-V318 HydrophobicContact CG1-CG1 3.87Å; F292-V318 HydrophobicContact CE1-CG2 4.25Å; F292-V318 HydrophobicContact CE2-CG2 3.96Å; F292-V318 HydrophobicContact CZ-CG2 3.42Å; F292-V318 VanDerWaalsContact CZ-CG2 3.42Å; I313-V318 HydrophobicContact CG2-CG1 3.63Å; P315-V318 VanDerWaalsContact O-CG2 3.32Å; P315-V318 WeakPolarHBondContact O-CG2 3.4Å; P315-V318 PolarHBondContact O-N 2.82Å; E316-V318 PolarHBondContact O-N 3.12Å; V318-V320 HydrophobicContact CG2-CG2 4.08Å
319G89.6Confident79.8Confident6 Ų660.3 Ų60.36%0.06231%0.309CS..THydrogen-bonded Turntrans102.69.7174.700000116.3N263 P315 E316N263-G319 WeakPolarHBondContact O-CA 3.46Å; P315-G319 PolarHBondContact O-N 3.18Å; E316-G319 PolarHBondContact O-N 3.44Å
320V83Confident79.4Confident37 Ų3762 Ų6222%0.22431%0.314CS..  trans-75.4128.6173-178.40000108.9V266 F292 P315 V318 H322V266-V320 HydrophobicContact CG1-CG2 4.48Å; V266-V320 HydrophobicContact CG2-CG2 3.82Å; F292-V320 HydrophobicContact CD2-CG2 4.2Å; F292-V320 HydrophobicContact CE2-CG2 3.89Å; P315-V320 HydrophobicContact CB-CB 3.61Å; P315-V320 HydrophobicContact CB-CG1 3.93Å; P315-V320 HydrophobicContact CB-CG2 4.34Å; P315-V320 WeakPolarHBondContact O-CB 3.33Å; P315-V320 PolarHBondContact O-N 3.14Å; V318-V320 HydrophobicContact CG2-CG2 4.08Å; V320-H322 WeakPolarHBondContact CG1-O 3.42Å
321K67.7Low79.2Confident179 Ų17957.7 Ų57.778%0.77830%0.297SS*.  trans-93.3-16.3-175.8-67.5-176.1179.8177.10114.8
322H57.1Low79.1Confident165 Ų16557.7 Ų57.776%0.76430%0.302SS*.  trans-134.3118-176.2-68-71.8000109.7V320V320-H322 WeakPolarHBondContact CG1-O 3.42Å
323N55.6Low78.8Confident80 Ų8057.2 Ų57.243%0.42829%0.292SS..  trans-82.9123.4169.8-140.35.6000107.7P315P315-N323 HydrophobicContact CG-CB 4.35Å; P315-N323 VanDerWaalsContact CG-CG 3.5Å; P315-N323 WeakPolarHBondContact CG-OD1 3.13Å
324S59.5Low78.5Confident74 Ų7459.1 Ų59.152%0.51730%0.3SS..  trans-100.2134.6172.668.80000109P326S324-P326 WeakPolarHBondContact O-CD 3.42Å
325L68.3Low78.2Confident26 Ų2656.4 Ų56.414%0.13628%0.283CS..  trans-97.384.4168.9-167.975.8000108.3Q300 L327 A335Q300-L325 HydrophobicContact CB-CD1 4.46Å; Q300-L325 HydrophobicContact CG-CD1 4.07Å; L325-L327 PolarHBondContact O-N 3.04Å; L325-A335 HydrophobicContact CD2-CB 4.29Å
326P70.1Confident78.2Confident48 Ų4856.4 Ų56.431%0.31228%0.283SS..  trans-65.3131.4-179.726.2-33.6000110Q300 S324Q300-P326 PolarHBondContact NE2-O 3.35Å; S324-P326 WeakPolarHBondContact O-CD 3.42Å
327L76.3Confident78.1Confident9 Ų952.5 Ų52.55%0.04727%0.266CS..BIsolated β-bridgetrans-94.7139.4170.7-68.2-175.2000110.1L325 S331 A335 F336 K339 F359 I369 I374L325-L327 PolarHBondContact O-N 3.04Å; L327-S331 WeakPolarHBondContact CA-OG 3.27Å; L327-A335 HydrophobicContact CD2-CB 4.19Å; L327-F336 HydrophobicContact CD1-CD2 3.97Å; L327-K339 HydrophobicContact CD1-CB 3.64Å; L327-K339 HydrophobicContact CD1-CG 3.55Å; L327-K339 HydrophobicContact CD2-CB 4.39Å; L327-K339 HydrophobicContact CG-CB 4.14Å; L327-K339 HydrophobicContact CG-CG 4.01Å; L327-F359 HydrophobicContact CB-CE2 3.83Å; L327-F359 HydrophobicContact CB-CZ 3.94Å; L327-F359 HydrophobicContact CD1-CE2 4.16Å; L327-F359 HydrophobicContact CD1-CZ 4.47Å; L327-I369 HydrophobicContact CB-CB 4.44Å; L327-I369 WeakPolarHBondContact O-CB 3.35Å; L327-I374 HydrophobicContact CD1-CD1 3.41Å; L327-I374 VanDerWaalsContact CD1-CD1 3.41Å; L327-I374 HydrophobicContact CD1-CG1 3.94Å
328G78.1Confident77.6Confident4 Ų452.5 Ų52.54%0.04127%0.265CS..  trans-154.2-170-179.700000112.3E295 L330 S331 F359E295-G328 WeakPolarHBondContact OE1-CA 3.47Å; G328-L330 PolarHBondContact O-N 3.48Å; G328-L330 VanDerWaalsContact O-N 3.11Å; G328-S331 PolarHBondContact N-OG 2.95Å; G328-S331 WeakPolarHBondContact O-CB 3.35Å; G328-S331 PolarHBondContact O-N 3.26Å; G328-S331 PolarHBondContact O-OG 3.44Å; G328-F359 VanDerWaalsContact O-CZ 3.22Å; G328-F359 WeakPolarHBondContact O-CZ 3.23Å
329K79.2Confident76.9Confident103 Ų10353.2 Ų53.245%0.44827%0.268SS..THydrogen-bonded Turntrans-58.4-30.4-176.6178.6171.3171.6135.20111.6E295 K360 A363 D364E295-K329 PolarHBondContact OE1-N 3.45Å; K329-K360 PolarHBondContact O-NZ 3.3Å; K329-A363 HydrophobicContact CB-CB 4.37Å; K329-D364 WeakPolarHBondContact CD-OD1 3.44Å; K329-D364 WeakPolarHBondContact CE-OD1 3.12Å; K329-D364 IonicContact NZ-OD1 3.68Å; K329-D364 PolarHBondContact NZ-OD1 3.42Å
330L79.7Confident76.5Confident105 Ų10552.9 Ų52.955%0.5527%0.265SS..THydrogen-bonded Turntrans-89.9-5.4-178-59.9179.2000114.2E295 G297 G328E295-L330 HydrophobicContact CG-CB 4.22Å; E295-L330 CarbonylContact O-C 3.2Å; E295-L330 PolarHBondContact OE1-N 2.89Å; G297-L330 PolarHBondContact N-O 2.88Å; G328-L330 PolarHBondContact O-N 3.48Å; G328-L330 VanDerWaalsContact O-N 3.11Å
331S81.9Confident76.4Confident1 Ų156.4 Ų56.41%0.00728%0.277CS..  trans-67.8145.1-174.2-56.60000113E295 Q300 L327 G328E295-S331 WeakPolarHBondContact O-CA 3.37Å; E295-S331 PolarHBondContact O-N 2.85Å; E295-S331 VanDerWaalsContact O-N 3.1Å; E295-S331 PolarHBondContact O-OG 3.14Å; E295-S331 VanDerWaalsContact O-OG 3.07Å; Q300-S331 PolarHBondContact NE2-OG 2.58Å; Q300-S331 VanDerWaalsContact OE1-CB 3.24Å; Q300-S331 PolarHBondContact OE1-OG 3.16Å; L327-S331 WeakPolarHBondContact CA-OG 3.27Å; G328-S331 PolarHBondContact N-OG 2.95Å; G328-S331 WeakPolarHBondContact O-CB 3.35Å; G328-S331 PolarHBondContact O-N 3.26Å; G328-S331 PolarHBondContact O-OG 3.44Å
332G84.1Confident76.7Confident16 Ų1652.9 Ų52.917%0.16526%0.263CS..  trans-93.6166-172.500000111.9G297 H334 A335 F336G297-G332 VanDerWaalsContact CA-CA 3.48Å; G332-H334 VanDerWaalsContact C-N 3.25Å; G332-H334 PolarHBondContact O-N 3Å; G332-A335 PolarHBondContact O-N 3.29Å; G332-F336 WeakPolarHBondContact O-CB 3.45Å; G332-F336 PolarHBondContact O-N 3.08Å
333R85.3Confident77.2Confident116 Ų11645.6 Ų45.644%0.43823%0.23SC..Hα-helixtrans-58.5-38.6178.4-175177.9174.4177.3-0.6111.9V337 I352 F356R333-V337 WeakPolarHBondContact O-CB 3.48Å; R333-V337 VanDerWaalsContact O-CG2 3.23Å; R333-V337 WeakPolarHBondContact O-CG2 3.46Å; R333-V337 PolarHBondContact O-N 2.67Å; R333-I352 HydrophobicContact CG-CG2 3.8Å; R333-F356 HydrophobicContact CB-CD1 4.28Å; R333-F356 HydrophobicContact CB-CD2 4.3Å; R333-F356 HydrophobicContact CB-CE1 4.24Å; R333-F356 HydrophobicContact CB-CE2 4.27Å; R333-F356 HydrophobicContact CB-CG 4.31Å; R333-F356 HydrophobicContact CB-CZ 4.23Å; R333-F356 HydrophobicContact CG-CG 4.39Å
334H83.1Confident77.8Confident68 Ų6848.6 Ų48.632%0.31524%0.241SC..Hα-helixtrans-66.4-47.2-179.7-169.249.4000112D301 G332 F336 V337 E338D301-H334 HydrophobicContact CB-CB 4.44Å; D301-H334 IonicContact OD1-CD2 3.34Å; D301-H334 PolarHBondContact OD1-CD2 2.94Å; D301-H334 IonicContact OD1-CG 3.68Å; G332-H334 VanDerWaalsContact C-N 3.25Å; G332-H334 PolarHBondContact O-N 3Å; H334-F336 VanDerWaalsContact C-N 3.34Å; H334-F336 PolarHBondContact O-N 3.41Å; H334-V337 WeakPolarHBondContact O-CB 3.31Å; H334-V337 PolarHBondContact O-N 2.89Å; H334-V337 VanDerWaalsContact O-N 3.12Å; H334-E338 IonicContact CE1-OE1 3.55Å; H334-E338 PolarHBondContact O-N 2.75Å
335A82.5Confident78.1Confident0 Ų045.7 Ų45.70%022%0.22CC..Hα-helixtrans-62.3-40.4176.500000113.1Q300 L325 L327 G332 V337 E338 K339Q300-A335 HydrophobicContact CB-CB 3.51Å; Q300-A335 HydrophobicContact CG-CB 3.93Å; L325-A335 HydrophobicContact CD2-CB 4.29Å; L327-A335 HydrophobicContact CD2-CB 4.19Å; G332-A335 PolarHBondContact O-N 3.29Å; A335-V337 VanDerWaalsContact C-N 3.33Å; A335-E338 PolarHBondContact O-N 3.18Å; A335-K339 WeakPolarHBondContact O-CB 3.28Å; A335-K339 PolarHBondContact O-N 3.36Å
336F86.1Confident77.7Confident0 Ų047.9 Ų47.90%024%0.242CC..Hα-helixtrans-59.6-45.5172.7179.2-108.3000110.9L327 G332 H334 K339 L340 L355 F356 F359 I374L327-F336 HydrophobicContact CD1-CD2 3.97Å; G332-F336 WeakPolarHBondContact O-CB 3.45Å; G332-F336 PolarHBondContact O-N 3.08Å; H334-F336 VanDerWaalsContact C-N 3.34Å; H334-F336 PolarHBondContact O-N 3.41Å; F336-K339 PolarHBondContact O-N 3.07Å; F336-L340 HydrophobicContact CD1-CD1 4.05Å; F336-L340 HydrophobicContact CD1-CG 4.44Å; F336-L340 HydrophobicContact CE1-CD1 3.61Å; F336-L340 HydrophobicContact CE1-CG 4.16Å; F336-L340 HydrophobicContact CE2-CD2 4.41Å; F336-L340 HydrophobicContact CZ-CD1 4.03Å; F336-L340 HydrophobicContact CZ-CD2 4.12Å; F336-L340 HydrophobicContact CZ-CG 4.21Å; F336-L340 WeakPolarHBondContact O-CG 3.42Å; F336-L340 PolarHBondContact O-N 2.83Å; F336-L355 HydrophobicContact CE1-CB 3.76Å; F336-L355 HydrophobicContact CZ-CB 3.99Å; F336-F356 HydrophobicContact CB-CD2 3.82Å; F336-F356 HydrophobicContact CB-CE2 4.13Å; F336-F356 HydrophobicContact CD1-CB 4.13Å; F336-F356 AromaticContact CD1-CD2 3.9Å; F336-F356 HydrophobicContact CD1-CD2 3.9Å; F336-F356 HydrophobicContact CE1-CB 4.31Å; F336-F356 AromaticContact CG-CD2 3.91Å; F336-F356 HydrophobicContact CG-CD2 3.91Å; F336-F359 HydrophobicContact CD2-CB 4Å; F336-F359 AromaticContact CD2-CD1 3.97Å; F336-F359 HydrophobicContact CD2-CD1 3.97Å; F336-F359 AromaticContact CD2-CD2 3.95Å; F336-F359 HydrophobicContact CD2-CD2 3.95Å; F336-F359 HydrophobicContact CD2-CE1 4.48Å; F336-F359 HydrophobicContact CD2-CE2 4.46Å; F336-F359 AromaticContact CD2-CG 3.67Å; F336-F359 HydrophobicContact CD2-CG 3.67Å; F336-F359 HydrophobicContact CE2-CB 3.59Å; F336-F359 HydrophobicContact CE2-CD1 4.43Å; F336-F359 AromaticContact CE2-CD2 3.98Å; F336-F359 HydrophobicContact CE2-CD2 3.98Å; F336-F359 AromaticContact CE2-CG 3.73Å; F336-F359 HydrophobicContact CE2-CG 3.73Å; F336-F359 HydrophobicContact CG-CD1 4.38Å; F336-F359 HydrophobicContact CG-CG 4.46Å; F336-F359 HydrophobicContact CZ-CB 3.99Å; F336-I374 HydrophobicContact CD2-CD1 4.15Å; F336-I374 HydrophobicContact CE2-CD1 3.82Å; F336-I374 HydrophobicContact CE2-CG2 4.2Å
337V85.9Confident77.7Confident16 Ų1648 Ų4810%0.09724%0.237CC..Hα-helixtrans-63.2-42.6176.3168.40000112.3R333 H334 A335 K339 L340 K341 F347 I352R333-V337 WeakPolarHBondContact O-CB 3.48Å; R333-V337 VanDerWaalsContact O-CG2 3.23Å; R333-V337 WeakPolarHBondContact O-CG2 3.46Å; R333-V337 PolarHBondContact O-N 2.67Å; H334-V337 WeakPolarHBondContact O-CB 3.31Å; H334-V337 PolarHBondContact O-N 2.89Å; H334-V337 VanDerWaalsContact O-N 3.12Å; A335-V337 VanDerWaalsContact C-N 3.33Å; V337-K339 VanDerWaalsContact C-N 3.33Å; V337-L340 WeakPolarHBondContact O-CB 3.24Å; V337-L340 PolarHBondContact O-N 2.85Å; V337-K341 HydrophobicContact CG1-CD 4.44Å; V337-K341 WeakPolarHBondContact O-CG 3.44Å; V337-K341 PolarHBondContact O-N 3.12Å; V337-F347 HydrophobicContact CG1-CE2 4.27Å; V337-F347 HydrophobicContact CG1-CZ 3.93Å; V337-I352 HydrophobicContact CG2-CD1 3.9Å; V337-I352 HydrophobicContact CG2-CG1 4.28Å; V337-I352 HydrophobicContact CG2-CG2 3.49Å; V337-I352 VanDerWaalsContact CG2-CG2 3.49Å
338E83.1Confident77.5Confident50 Ų5053.7 Ų53.723%0.23426%0.264CS..Hα-helixtrans-65.2-38176.1-68.9-52.3124.600111.5L304 H334 A335 K341 E342L304-E338 HydrophobicContact CD1-CB 4.02Å; L304-E338 HydrophobicContact CD1-CG 3.57Å; L304-E338 HydrophobicContact CD2-CB 4.18Å; L304-E338 HydrophobicContact CD2-CG 3.92Å; L304-E338 HydrophobicContact CG-CG 4.3Å; H334-E338 IonicContact CE1-OE1 3.55Å; H334-E338 PolarHBondContact O-N 2.75Å; A335-E338 PolarHBondContact O-N 3.18Å; E338-K341 WeakPolarHBondContact O-CB 3.39Å; E338-K341 PolarHBondContact O-N 3.03Å; E338-K341 IonicContact OE1-NZ 2.71Å; E338-K341 PolarHBondContact OE1-NZ 2.96Å; E338-E342 WeakPolarHBondContact O-CB 3.27Å; E338-E342 PolarHBondContact O-N 3.14Å
339K79.7Confident77.4Confident14 Ų1461 Ų616%0.06130%0.297CS..Hα-helixtrans-65.3-38.6172.9-166.456.3144.8155.60112.2L327 A335 F336 V337 K341 E342 L343 D371L327-K339 HydrophobicContact CD1-CB 3.64Å; L327-K339 HydrophobicContact CD1-CG 3.55Å; L327-K339 HydrophobicContact CD2-CB 4.39Å; L327-K339 HydrophobicContact CG-CB 4.14Å; L327-K339 HydrophobicContact CG-CG 4.01Å; A335-K339 WeakPolarHBondContact O-CB 3.28Å; A335-K339 PolarHBondContact O-N 3.36Å; F336-K339 PolarHBondContact O-N 3.07Å; V337-K339 VanDerWaalsContact C-N 3.33Å; K339-K341 VanDerWaalsContact C-N 3.3Å; K339-K341 PolarHBondContact O-N 3.26Å; K339-E342 HydrophobicContact CD-CB 4.44Å; K339-E342 VanDerWaalsContact CD-OE2 3.26Å; K339-E342 WeakPolarHBondContact CD-OE2 3.43Å; K339-E342 IonicContact NZ-OE1 2.75Å; K339-E342 PolarHBondContact NZ-OE1 2.75Å; K339-E342 IonicContact NZ-OE2 3.67Å; K339-E342 PolarHBondContact O-N 3.14Å; K339-L343 HydrophobicContact CD-CD1 4.45Å; K339-L343 HydrophobicContact CD-CG 4.35Å; K339-L343 HydrophobicContact CG-CD1 4.16Å; K339-L343 HydrophobicContact CG-CG 4.46Å; K339-L343 WeakPolarHBondContact O-CB 3.37Å; K339-L343 VanDerWaalsContact O-CG 3.22Å; K339-L343 WeakPolarHBondContact O-CG 3.26Å; K339-L343 PolarHBondContact O-N 2.8Å; K339-D371 WeakPolarHBondContact CE-OD1 3.3Å; K339-D371 IonicContact NZ-OD1 3.32Å; K339-D371 PolarHBondContact NZ-OD1 3.32Å; K339-D371 IonicContact NZ-OD2 3.69Å
340L81Confident77.4Confident0 Ų060.7 Ų60.70%031%0.308CS..Hα-helixtrans-60.2-41.3172.4-68.8-179.5000111.6F336 V337 E344 L345 F347 L355 I374 V378F336-L340 HydrophobicContact CD1-CD1 4.05Å; F336-L340 HydrophobicContact CD1-CG 4.44Å; F336-L340 HydrophobicContact CE1-CD1 3.61Å; F336-L340 HydrophobicContact CE1-CG 4.16Å; F336-L340 HydrophobicContact CE2-CD2 4.41Å; F336-L340 HydrophobicContact CZ-CD1 4.03Å; F336-L340 HydrophobicContact CZ-CD2 4.12Å; F336-L340 HydrophobicContact CZ-CG 4.21Å; F336-L340 WeakPolarHBondContact O-CG 3.42Å; F336-L340 PolarHBondContact O-N 2.83Å; V337-L340 WeakPolarHBondContact O-CB 3.24Å; V337-L340 PolarHBondContact O-N 2.85Å; L340-E344 PolarHBondContact O-N 2.67Å; L340-L345 HydrophobicContact CD2-CB 4.31Å; L340-L345 HydrophobicContact CD2-CD1 3.76Å; L340-L345 PolarHBondContact O-N 3.02Å; L340-F347 HydrophobicContact CB-CD1 3.71Å; L340-F347 HydrophobicContact CB-CE1 3.49Å; L340-F347 VanDerWaalsContact CB-CE1 3.49Å; L340-F347 HydrophobicContact CB-CZ 4.38Å; L340-F347 HydrophobicContact CD1-CB 4.5Å; L340-F347 HydrophobicContact CD1-CD1 3.72Å; L340-F347 HydrophobicContact CD1-CE1 4.08Å; L340-F347 HydrophobicContact CD1-CG 4.01Å; L340-F347 HydrophobicContact CG-CD1 4.32Å; L340-F347 HydrophobicContact CG-CE1 4.45Å; L340-L355 HydrophobicContact CD1-CD1 4.43Å; L340-I374 HydrophobicContact CD2-CG2 3.5Å; L340-I374 VanDerWaalsContact CD2-CG2 3.5Å; L340-V378 HydrophobicContact CD2-CG2 3.51Å
341K79.2Confident77.3Confident111 Ų11160 Ų6048%0.48330%0.302SS..Hα-helixtrans-67.7-43.6175.2-67.5171.5-175.6171.40112.3V337 E338 K339 L343 E344 F347V337-K341 HydrophobicContact CG1-CD 4.44Å; V337-K341 WeakPolarHBondContact O-CG 3.44Å; V337-K341 PolarHBondContact O-N 3.12Å; E338-K341 WeakPolarHBondContact O-CB 3.39Å; E338-K341 PolarHBondContact O-N 3.03Å; E338-K341 IonicContact OE1-NZ 2.71Å; E338-K341 PolarHBondContact OE1-NZ 2.96Å; K339-K341 VanDerWaalsContact C-N 3.3Å; K339-K341 PolarHBondContact O-N 3.26Å; K341-L343 VanDerWaalsContact C-N 3.27Å; K341-L343 PolarHBondContact O-N 2.82Å; K341-E344 PolarHBondContact O-N 2.79Å; K341-F347 HydrophobicContact CG-CE1 4.22Å; K341-F347 HydrophobicContact CG-CZ 4.13Å
342E74.7Confident77.4Confident104 Ų10460.4 Ų60.449%0.48630%0.304SS..Hα-helixtrans-58.3-39.2176-176.6-166.1139.300111.4E338 K339 E344E338-E342 WeakPolarHBondContact O-CB 3.27Å; E338-E342 PolarHBondContact O-N 3.14Å; K339-E342 HydrophobicContact CD-CB 4.44Å; K339-E342 VanDerWaalsContact CD-OE2 3.26Å; K339-E342 WeakPolarHBondContact CD-OE2 3.43Å; K339-E342 IonicContact NZ-OE1 2.75Å; K339-E342 PolarHBondContact NZ-OE1 2.75Å; K339-E342 IonicContact NZ-OE2 3.67Å; K339-E342 PolarHBondContact O-N 3.14Å; E342-E344 PolarHBondContact O-N 3.41Å
343L68.1Low77.4Confident13 Ų1362.5 Ų62.57%0.06832%0.319CS..THydrogen-bonded Turntrans-82.62.7177.4-63.9178.6000114.1K339 K341 L345 D371 I374 R375K339-L343 HydrophobicContact CD-CD1 4.45Å; K339-L343 HydrophobicContact CD-CG 4.35Å; K339-L343 HydrophobicContact CG-CD1 4.16Å; K339-L343 HydrophobicContact CG-CG 4.46Å; K339-L343 WeakPolarHBondContact O-CB 3.37Å; K339-L343 VanDerWaalsContact O-CG 3.22Å; K339-L343 WeakPolarHBondContact O-CG 3.26Å; K339-L343 PolarHBondContact O-N 2.8Å; K341-L343 VanDerWaalsContact C-N 3.27Å; K341-L343 PolarHBondContact O-N 2.82Å; L343-L345 HydrophobicContact CB-CD1 3.91Å; L343-L345 HydrophobicContact CB-CG 3.94Å; L343-L345 HydrophobicContact CD1-CD1 4.15Å; L343-L345 PolarHBondContact O-N 3.18Å; L343-D371 HydrophobicContact CD1-CB 3.96Å; L343-D371 HydrophobicContact CD2-CB 3.72Å; L343-D371 VanDerWaalsContact CD2-CG 3.48Å; L343-I374 HydrophobicContact CD1-CB 3.97Å; L343-I374 HydrophobicContact CD1-CG2 3.91Å; L343-R375 PolarHBondContact O-NH1 2.92Å; L343-R375 PolarHBondContact O-NH2 2.81Å
344E68.8Low77.4Confident142 Ų14261.3 Ų61.366%0.66433%0.325SS*.THydrogen-bonded Turntrans54.236.8-177.8-56.9-175.9163.400112.8L340 K341 E342L340-E344 PolarHBondContact O-N 2.67Å; K341-E344 PolarHBondContact O-N 2.79Å; E342-E344 PolarHBondContact O-N 3.41Å
345L64.9Low77.5Confident14 Ų1458.7 Ų58.77%0.07331%0.313CS..  trans-86.3128.7178.7-67.7170.9000110.5L340 L343 F347 I374 R375 V378L340-L345 HydrophobicContact CD2-CB 4.31Å; L340-L345 HydrophobicContact CD2-CD1 3.76Å; L340-L345 PolarHBondContact O-N 3.02Å; L343-L345 HydrophobicContact CB-CD1 3.91Å; L343-L345 HydrophobicContact CB-CG 3.94Å; L343-L345 HydrophobicContact CD1-CD1 4.15Å; L343-L345 PolarHBondContact O-N 3.18Å; L345-F347 WeakPolarHBondContact O-CD1 3.31Å; L345-I374 HydrophobicContact CD1-CG2 4.05Å; L345-R375 HydrophobicContact CD1-CG 4Å; L345-R375 HydrophobicContact CD2-CG 4.06Å; L345-R375 HydrophobicContact CG-CG 4.49Å; L345-V378 HydrophobicContact CD1-CG2 3.99Å
346A59.3Low77.8Confident71 Ų7160.7 Ų60.759%0.58732%0.322SS*.  trans-72.9131.7173.200000110.5
347F71Confident77.8Confident51 Ų5162.2 Ų62.222%0.22434%0.338CS..  trans-149.9145.2173.358.9-89.5000109.6V337 L340 K341 L345 I352 L355V337-F347 HydrophobicContact CG1-CE2 4.27Å; V337-F347 HydrophobicContact CG1-CZ 3.93Å; L340-F347 HydrophobicContact CB-CD1 3.71Å; L340-F347 HydrophobicContact CB-CE1 3.49Å; L340-F347 VanDerWaalsContact CB-CE1 3.49Å; L340-F347 HydrophobicContact CB-CZ 4.38Å; L340-F347 HydrophobicContact CD1-CB 4.5Å; L340-F347 HydrophobicContact CD1-CD1 3.72Å; L340-F347 HydrophobicContact CD1-CE1 4.08Å; L340-F347 HydrophobicContact CD1-CG 4.01Å; L340-F347 HydrophobicContact CG-CD1 4.32Å; L340-F347 HydrophobicContact CG-CE1 4.45Å; K341-F347 HydrophobicContact CG-CE1 4.22Å; K341-F347 HydrophobicContact CG-CZ 4.13Å; L345-F347 WeakPolarHBondContact O-CD1 3.31Å; F347-I352 HydrophobicContact CD2-CD1 3.94Å; F347-I352 HydrophobicContact CD2-CG1 3.61Å; F347-I352 HydrophobicContact CE2-CD1 3.72Å; F347-I352 HydrophobicContact CE2-CG1 3.9Å; F347-L355 HydrophobicContact CB-CD1 4.11Å
348E71.7Confident77.6Confident129 Ų12965.5 Ų65.560%0.60335%0.351SS*.  trans-85148.6169.2-69.9-68159.400110.4S350 E351 I352E348-S350 PolarHBondContact O-N 3.08Å; E348-S350 VanDerWaalsContact O-N 3.1Å; E348-E351 HydrophobicContact CB-CG 4.02Å; E348-E351 PolarHBondContact N-OE2 3.44Å; E348-E351 WeakPolarHBondContact O-CB 3.33Å; E348-E351 PolarHBondContact O-N 3.41Å; E348-I352 PolarHBondContact O-N 3.24Å
349E76.6Confident77.8Confident156 Ų15663.1 Ų63.173%0.72934%0.34SS*.THydrogen-bonded Turntrans-59.5-29179.7-166.7171-17600112.1E351 I352E349-E351 VanDerWaalsContact C-N 3.31Å; E349-E351 PolarHBondContact O-N 3.25Å; E349-I352 HydrophobicContact CB-CD1 4.42Å; E349-I352 HydrophobicContact CG-CD1 4.03Å
350S79.6Confident78Confident97 Ų9765.6 Ų65.668%0.67835%0.351SS*.THydrogen-bonded Turntrans-66.8-25.5172.752.90000114.2E348E348-S350 PolarHBondContact O-N 3.08Å; E348-S350 VanDerWaalsContact O-N 3.1Å
351E77.3Confident78.1Confident91 Ų9173 Ų7343%0.42538%0.383SS..THydrogen-bonded Turntrans-86.1-23.1-176.8-66.3176.7141.600112.8E348 E349 A353 T354 L355E348-E351 HydrophobicContact CB-CG 4.02Å; E348-E351 PolarHBondContact N-OE2 3.44Å; E348-E351 WeakPolarHBondContact O-CB 3.33Å; E348-E351 PolarHBondContact O-N 3.41Å; E349-E351 VanDerWaalsContact C-N 3.31Å; E349-E351 PolarHBondContact O-N 3.25Å; E351-A353 PolarHBondContact O-N 3.13Å; E351-A353 VanDerWaalsContact O-N 3.12Å; E351-T354 WeakPolarHBondContact O-CB 3.32Å; E351-T354 PolarHBondContact O-N 2.68Å; E351-L355 HydrophobicContact CB-CD1 4.18Å; E351-L355 HydrophobicContact CB-CG 4.46Å; E351-L355 PolarHBondContact O-N 2.93Å
352I84.1Confident78Confident10 Ų1069.7 Ų69.75%0.05137%0.37CS..Hα-helixtrans-54.4-39.9-174.1-58.5171.9000111.6R333 V337 F347 E348 E349 T354 F356R333-I352 HydrophobicContact CG-CG2 3.8Å; V337-I352 HydrophobicContact CG2-CD1 3.9Å; V337-I352 HydrophobicContact CG2-CG1 4.28Å; V337-I352 HydrophobicContact CG2-CG2 3.49Å; V337-I352 VanDerWaalsContact CG2-CG2 3.49Å; F347-I352 HydrophobicContact CD2-CD1 3.94Å; F347-I352 HydrophobicContact CD2-CG1 3.61Å; F347-I352 HydrophobicContact CE2-CD1 3.72Å; F347-I352 HydrophobicContact CE2-CG1 3.9Å; E348-I352 PolarHBondContact O-N 3.24Å; E349-I352 HydrophobicContact CB-CD1 4.42Å; E349-I352 HydrophobicContact CG-CD1 4.03Å; I352-T354 VanDerWaalsContact C-N 3.34Å; I352-T354 PolarHBondContact O-N 2.94Å; I352-F356 WeakPolarHBondContact O-CB 3.26Å; I352-F356 PolarHBondContact O-N 3Å
353A84.5Confident78.1Confident59 Ų5965 Ų6549%0.48835%0.349SS..Hα-helixtrans-63.5-40.5179.700000112.2E351 G357E351-A353 PolarHBondContact O-N 3.13Å; E351-A353 VanDerWaalsContact O-N 3.12Å; A353-G357 PolarHBondContact O-N 3.48Å
354T84.9Confident78.6Confident91 Ų9168.7 Ų68.756%0.55837%0.369SS*.Hα-helixtrans-70.7-48.9178.3-57.60000111E351 I352 F356 G357 K358E351-T354 WeakPolarHBondContact O-CB 3.32Å; E351-T354 PolarHBondContact O-N 2.68Å; I352-T354 VanDerWaalsContact C-N 3.34Å; I352-T354 PolarHBondContact O-N 2.94Å; T354-F356 PolarHBondContact O-N 3.38Å; T354-G357 PolarHBondContact O-N 3.39Å; T354-G357 VanDerWaalsContact O-N 3.15Å; T354-K358 PolarHBondContact O-N 3.22Å
355L84.2Confident78.8Confident13 Ų1369.8 Ų69.87%0.06837%0.372CS..Hα-helixtrans-60.7-45.2178.7-69.7175.3000111.5F336 L340 F347 E351 G357 K358 F359 L377 V378F336-L355 HydrophobicContact CE1-CB 3.76Å; F336-L355 HydrophobicContact CZ-CB 3.99Å; L340-L355 HydrophobicContact CD1-CD1 4.43Å; F347-L355 HydrophobicContact CB-CD1 4.11Å; E351-L355 HydrophobicContact CB-CD1 4.18Å; E351-L355 HydrophobicContact CB-CG 4.46Å; E351-L355 PolarHBondContact O-N 2.93Å; L355-G357 VanDerWaalsContact C-N 3.3Å; L355-G357 PolarHBondContact O-N 3.16Å; L355-K358 PolarHBondContact O-N 2.84Å; L355-K358 VanDerWaalsContact O-N 3.17Å; L355-F359 WeakPolarHBondContact O-CB 3.46Å; L355-F359 PolarHBondContact O-N 2.86Å; L355-L377 WeakPolarHBondContact CD2-O 3.46Å; L355-V378 HydrophobicContact CD1-CG2 4.22Å; L355-V378 HydrophobicContact CD2-CG2 4.37Å
356F88.3Confident78.9Confident42 Ų4272.2 Ų72.218%0.18438%0.381CS..Hα-helixtrans-61.9-39.2175.5-173.2-112.2000111.5R333 F336 I352 T354 K358 F359 K360R333-F356 HydrophobicContact CB-CD1 4.28Å; R333-F356 HydrophobicContact CB-CD2 4.3Å; R333-F356 HydrophobicContact CB-CE1 4.24Å; R333-F356 HydrophobicContact CB-CE2 4.27Å; R333-F356 HydrophobicContact CB-CG 4.31Å; R333-F356 HydrophobicContact CB-CZ 4.23Å; R333-F356 HydrophobicContact CG-CG 4.39Å; F336-F356 HydrophobicContact CB-CD2 3.82Å; F336-F356 HydrophobicContact CB-CE2 4.13Å; F336-F356 HydrophobicContact CD1-CB 4.13Å; F336-F356 AromaticContact CD1-CD2 3.9Å; F336-F356 HydrophobicContact CD1-CD2 3.9Å; F336-F356 HydrophobicContact CE1-CB 4.31Å; F336-F356 AromaticContact CG-CD2 3.91Å; F336-F356 HydrophobicContact CG-CD2 3.91Å; I352-F356 WeakPolarHBondContact O-CB 3.26Å; I352-F356 PolarHBondContact O-N 3Å; T354-F356 PolarHBondContact O-N 3.38Å; F356-K358 PolarHBondContact O-N 3.39Å; F356-F359 AromaticContact CD2-CD1 3.81Å; F356-F359 HydrophobicContact CD2-CD1 3.81Å; F356-F359 HydrophobicContact CD2-CE1 4.43Å; F356-F359 AromaticContact CE2-CD1 3.81Å; F356-F359 HydrophobicContact CE2-CD1 3.81Å; F356-F359 HydrophobicContact CE2-CE1 4.01Å; F356-F359 WeakPolarHBondContact O-CB 3.34Å; F356-F359 PolarHBondContact O-N 2.87Å; F356-K360 HydrophobicContact CD1-CG 4.3Å; F356-K360 HydrophobicContact CE1-CD 4.24Å; F356-K360 HydrophobicContact CE1-CG 3.99Å; F356-K360 HydrophobicContact CE2-CD 4.28Å; F356-K360 HydrophobicContact CE2-CG 4.37Å; F356-K360 HydrophobicContact CZ-CD 3.86Å; F356-K360 HydrophobicContact CZ-CG 4.03Å; F356-K360 VanDerWaalsContact O-CG 3.25Å; F356-K360 WeakPolarHBondContact O-CG 3.45Å; F356-K360 PolarHBondContact O-N 2.89Å
357G86Confident79Confident33 Ų3378.3 Ų78.334%0.3440%0.398SS..Hα-helixtrans-60.7-41.7173.300000113.4A353 T354 L355 K361A353-G357 PolarHBondContact O-N 3.48Å; T354-G357 PolarHBondContact O-N 3.39Å; T354-G357 VanDerWaalsContact O-N 3.15Å; L355-G357 VanDerWaalsContact C-N 3.3Å; L355-G357 PolarHBondContact O-N 3.16Å; G357-K361 PolarHBondContact O-N 2.75Å
358K83.3Confident78.9Confident84 Ų8481.9 Ų81.937%0.36542%0.415SS..Hα-helixtrans-67.7-44.2174.6-65.5-176178.9-1770111.6T354 L355 F356 K360 K361 L362 L377T354-K358 PolarHBondContact O-N 3.22Å; L355-K358 PolarHBondContact O-N 2.84Å; L355-K358 VanDerWaalsContact O-N 3.17Å; F356-K358 PolarHBondContact O-N 3.39Å; K358-K360 VanDerWaalsContact C-N 3.32Å; K358-K360 PolarHBondContact O-N 2.85Å; K358-K361 WeakPolarHBondContact O-CB 3.44Å; K358-K361 PolarHBondContact O-N 3.32Å; K358-K361 VanDerWaalsContact O-N 3.14Å; K358-L362 PolarHBondContact O-N 2.84Å; K358-L377 HydrophobicContact CB-CD2 3.52Å
359F85.9Confident78.9Confident0 Ų076.4 Ų76.40%039%0.39CS..Hα-helixtrans-53.8-47.5174162.9-105.5000111.8L327 G328 F336 L355 F356 K361 L362 A363 I369 I374 L377L327-F359 HydrophobicContact CB-CE2 3.83Å; L327-F359 HydrophobicContact CB-CZ 3.94Å; L327-F359 HydrophobicContact CD1-CE2 4.16Å; L327-F359 HydrophobicContact CD1-CZ 4.47Å; G328-F359 VanDerWaalsContact O-CZ 3.22Å; G328-F359 WeakPolarHBondContact O-CZ 3.23Å; F336-F359 HydrophobicContact CD2-CB 4Å; F336-F359 AromaticContact CD2-CD1 3.97Å; F336-F359 HydrophobicContact CD2-CD1 3.97Å; F336-F359 AromaticContact CD2-CD2 3.95Å; F336-F359 HydrophobicContact CD2-CD2 3.95Å; F336-F359 HydrophobicContact CD2-CE1 4.48Å; F336-F359 HydrophobicContact CD2-CE2 4.46Å; F336-F359 AromaticContact CD2-CG 3.67Å; F336-F359 HydrophobicContact CD2-CG 3.67Å; F336-F359 HydrophobicContact CE2-CB 3.59Å; F336-F359 HydrophobicContact CE2-CD1 4.43Å; F336-F359 AromaticContact CE2-CD2 3.98Å; F336-F359 HydrophobicContact CE2-CD2 3.98Å; F336-F359 AromaticContact CE2-CG 3.73Å; F336-F359 HydrophobicContact CE2-CG 3.73Å; F336-F359 HydrophobicContact CG-CD1 4.38Å; F336-F359 HydrophobicContact CG-CG 4.46Å; F336-F359 HydrophobicContact CZ-CB 3.99Å; L355-F359 WeakPolarHBondContact O-CB 3.46Å; L355-F359 PolarHBondContact O-N 2.86Å; F356-F359 AromaticContact CD2-CD1 3.81Å; F356-F359 HydrophobicContact CD2-CD1 3.81Å; F356-F359 HydrophobicContact CD2-CE1 4.43Å; F356-F359 AromaticContact CE2-CD1 3.81Å; F356-F359 HydrophobicContact CE2-CD1 3.81Å; F356-F359 HydrophobicContact CE2-CE1 4.01Å; F356-F359 WeakPolarHBondContact O-CB 3.34Å; F356-F359 PolarHBondContact O-N 2.87Å; F359-K361 VanDerWaalsContact C-N 3.32Å; F359-K361 PolarHBondContact O-N 2.91Å; F359-L362 PolarHBondContact O-N 3.19Å; F359-L362 VanDerWaalsContact O-N 3.11Å; F359-A363 HydrophobicContact CE2-CB 4.27Å; F359-A363 HydrophobicContact CZ-CB 4.31Å; F359-A363 WeakPolarHBondContact O-CB 3.47Å; F359-A363 PolarHBondContact O-N 2.68Å; F359-I369 HydrophobicContact CD2-CG2 4.42Å; F359-I369 HydrophobicContact CE2-CB 4.43Å; F359-I369 HydrophobicContact CE2-CG1 4.16Å; F359-I369 HydrophobicContact CE2-CG2 4.08Å; F359-I374 HydrophobicContact CD2-CD1 3.73Å; F359-I374 HydrophobicContact CE2-CD1 4Å; F359-L377 HydrophobicContact CB-CD1 3.87Å; F359-L377 HydrophobicContact CD2-CD1 4.21Å
360K84.9Confident78.7Confident67 Ų6769.5 Ų69.529%0.29136%0.358SS..Hα-helixtrans-59.9-40.9177.8-70.7-66.9-64.3-170.10112.4K329 F356 K358 D364K329-K360 PolarHBondContact O-NZ 3.3Å; F356-K360 HydrophobicContact CD1-CG 4.3Å; F356-K360 HydrophobicContact CE1-CD 4.24Å; F356-K360 HydrophobicContact CE1-CG 3.99Å; F356-K360 HydrophobicContact CE2-CD 4.28Å; F356-K360 HydrophobicContact CE2-CG 4.37Å; F356-K360 HydrophobicContact CZ-CD 3.86Å; F356-K360 HydrophobicContact CZ-CG 4.03Å; F356-K360 VanDerWaalsContact O-CG 3.25Å; F356-K360 WeakPolarHBondContact O-CG 3.45Å; F356-K360 PolarHBondContact O-N 2.89Å; K358-K360 VanDerWaalsContact C-N 3.32Å; K358-K360 PolarHBondContact O-N 2.85Å; K360-D364 WeakPolarHBondContact O-CB 3.48Å; K360-D364 PolarHBondContact O-N 2.94Å
361K82.3Confident78.4Confident156 Ų15667.3 Ų67.368%0.67834%0.339SS*.Hα-helixtrans-65-38.4174.8-70.6-179.7179.4-176.60112.5G357 K358 F359 D364G357-K361 PolarHBondContact O-N 2.75Å; K358-K361 WeakPolarHBondContact O-CB 3.44Å; K358-K361 PolarHBondContact O-N 3.32Å; K358-K361 VanDerWaalsContact O-N 3.14Å; F359-K361 VanDerWaalsContact C-N 3.32Å; F359-K361 PolarHBondContact O-N 2.91Å; K361-D364 PolarHBondContact O-N 2.92Å
362L77.2Confident77.7Confident41 Ų4163 Ų6322%0.21532%0.319CS..Hα-helixtrans-69-46.2177.6-175.461.7000111.1K358 F359 D364 K365 K366 I369 D373 L377K358-L362 PolarHBondContact O-N 2.84Å; F359-L362 PolarHBondContact O-N 3.19Å; F359-L362 VanDerWaalsContact O-N 3.11Å; L362-D364 PolarHBondContact O-N 3.4Å; L362-K365 CarbonylContact O-C 3.48Å; L362-K365 PolarHBondContact O-N 3.14Å; L362-K366 PolarHBondContact O-N 3.17Å; L362-I369 HydrophobicContact CB-CD1 4.42Å; L362-I369 HydrophobicContact CD2-CD1 4.07Å; L362-I369 HydrophobicContact CG-CD1 3.78Å; L362-D373 HydrophobicContact CD2-CB 3.69Å; L362-L377 HydrophobicContact CB-CD1 4.41Å; L362-L377 HydrophobicContact CB-CD2 4.34Å; L362-L377 HydrophobicContact CD2-CD1 3.7Å; L362-L377 HydrophobicContact CD2-CD2 4.22Å; L362-L377 HydrophobicContact CD2-CG 3.95Å
363A77.5Confident77.1Confident6 Ų663 Ų635%0.0532%0.319CS..Hα-helixtrans-66-20.8176.400000113.5K329 F359 K365 I369K329-A363 HydrophobicContact CB-CB 4.37Å; F359-A363 HydrophobicContact CE2-CB 4.27Å; F359-A363 HydrophobicContact CZ-CB 4.31Å; F359-A363 WeakPolarHBondContact O-CB 3.47Å; F359-A363 PolarHBondContact O-N 2.68Å; A363-K365 VanDerWaalsContact C-N 3.31Å; A363-I369 HydrophobicContact CB-CD1 4.16Å; A363-I369 HydrophobicContact CB-CG1 4.02Å
364D77.6Confident76.6Confident90 Ų9060.3 Ų60.348%0.48130%0.296SS..Hα-helixtrans-72.1-24.3168.9-84.3-29.3000113.1K329 K360 K361 L362K329-D364 WeakPolarHBondContact CD-OD1 3.44Å; K329-D364 WeakPolarHBondContact CE-OD1 3.12Å; K329-D364 IonicContact NZ-OD1 3.68Å; K329-D364 PolarHBondContact NZ-OD1 3.42Å; K360-D364 WeakPolarHBondContact O-CB 3.48Å; K360-D364 PolarHBondContact O-N 2.94Å; K361-D364 PolarHBondContact O-N 2.92Å; L362-D364 PolarHBondContact O-N 3.4Å
365K72.8Confident75.7Confident164 Ų16457.4 Ų57.471%0.71328%0.275SS*.Hα-helixtrans-103.1-29.8-177.8-67.8-176.3175.3-172.90113.6L362 A363 E384L362-K365 CarbonylContact O-C 3.48Å; L362-K365 PolarHBondContact O-N 3.14Å; A363-K365 VanDerWaalsContact C-N 3.31Å; K365-E384 IonicContact NZ-OE1 2.61Å
366K67.9Low74.7Confident65 Ų6556.8 Ų56.828%0.28327%0.272SS..  trans-115.2130.5-173.3-164.9-178.6-175.5-173.40110.7L362 E368 I369 D373L362-K366 PolarHBondContact O-N 3.17Å; K366-E368 VanDerWaalsContact CD-O 3.22Å; K366-E368 WeakPolarHBondContact CD-O 2.97Å; K366-E368 WeakPolarHBondContact CE-O 3.45Å; K366-E368 WeakPolarHBondContact CG-O 3.27Å; K366-I369 HydrophobicContact CB-CD1 3.99Å; K366-I369 HydrophobicContact CD-CD1 4.29Å; K366-I369 HydrophobicContact CG-CD1 4.49Å; K366-D373 WeakPolarHBondContact CD-OD2 3.44Å; K366-D373 WeakPolarHBondContact CE-OD2 3.42Å; K366-D373 IonicContact NZ-OD1 3.23Å; K366-D373 PolarHBondContact NZ-OD1 2.73Å; K366-D373 IonicContact NZ-OD2 3.35Å; K366-D373 PolarHBondContact NZ-OD2 3.32Å
367H62.3Low73.9Confident200 Ų20055.6 Ų55.693%0.92627%0.267SS*.SBendtrans-70.4-35.9-177.8-77.4-68.1000113.9
368E68Low73Confident126 Ų12655.9 Ų55.959%0.58926%0.263SS*.SBendtrans-124.6117.9-179.8-175.6175.6-179.300108.7K366K366-E368 VanDerWaalsContact CD-O 3.22Å; K366-E368 WeakPolarHBondContact CD-O 2.97Å; K366-E368 WeakPolarHBondContact CE-O 3.45Å; K366-E368 WeakPolarHBondContact CG-O 3.27Å
369I72.3Confident72Confident13 Ų1353.9 Ų53.97%0.06726%0.262CS..BIsolated β-bridgetrans-93.8118.2175.7-55.6-65.8000108.2L327 F359 L362 A363 K366 D373 I374L327-I369 HydrophobicContact CB-CB 4.44Å; L327-I369 WeakPolarHBondContact O-CB 3.35Å; F359-I369 HydrophobicContact CD2-CG2 4.42Å; F359-I369 HydrophobicContact CE2-CB 4.43Å; F359-I369 HydrophobicContact CE2-CG1 4.16Å; F359-I369 HydrophobicContact CE2-CG2 4.08Å; L362-I369 HydrophobicContact CB-CD1 4.42Å; L362-I369 HydrophobicContact CD2-CD1 4.07Å; L362-I369 HydrophobicContact CG-CD1 3.78Å; A363-I369 HydrophobicContact CB-CD1 4.16Å; A363-I369 HydrophobicContact CB-CG1 4.02Å; K366-I369 HydrophobicContact CB-CD1 3.99Å; K366-I369 HydrophobicContact CD-CD1 4.29Å; K366-I369 HydrophobicContact CG-CD1 4.49Å; I369-D373 WeakPolarHBondContact CA-OD2 3.13Å; I369-D373 HydrophobicContact CG2-CB 3.78Å; I369-I374 HydrophobicContact CG2-CD1 3.54Å; I369-I374 HydrophobicContact CG2-CG1 3.94Å
370T72.6Confident70.5Confident12 Ų1256 Ų567%0.07428%0.283CS..  trans-93.5165.3-178.974.60000110.5A372 D373 I374 N477T370-A372 PolarHBondContact O-N 3Å; T370-A372 PolarHBondContact OG1-N 3.04Å; T370-D373 PolarHBondContact N-OD2 3.09Å; T370-D373 WeakPolarHBondContact O-CB 3.22Å; T370-D373 PolarHBondContact O-N 2.77Å; T370-D373 VanDerWaalsContact O-N 3.09Å; T370-D373 PolarHBondContact OG1-N 2.75Å; T370-D373 PolarHBondContact OG1-OD2 2.8Å; T370-I374 PolarHBondContact O-N 2.75Å; T370-N477 HydrophobicContact CG2-CB 3.94Å; T370-N477 WeakPolarHBondContact CG2-ND2 3.43Å
371D72.7Confident68.4Low50 Ų5053.9 Ų53.927%0.26728%0.276SS..Hα-helixtrans-57.9-35.9175-66.5-20.7000111.7K339 L343 D373 I374 R375K339-D371 WeakPolarHBondContact CE-OD1 3.3Å; K339-D371 IonicContact NZ-OD1 3.32Å; K339-D371 PolarHBondContact NZ-OD1 3.32Å; K339-D371 IonicContact NZ-OD2 3.69Å; L343-D371 HydrophobicContact CD1-CB 3.96Å; L343-D371 HydrophobicContact CD2-CB 3.72Å; L343-D371 VanDerWaalsContact CD2-CG 3.48Å; D371-D373 PolarHBondContact O-N 2.95Å; D371-I374 WeakPolarHBondContact O-CB 3.33Å; D371-I374 PolarHBondContact O-N 3.42Å; D371-R375 WeakPolarHBondContact O-CG 3.32Å; D371-R375 PolarHBondContact O-N 3.33Å
372A62Low66.3Low1 Ų154.6 Ų54.61%0.00828%0.282CS..Hα-helixtrans-62.3-40.2173.900000114.2T370 I374 R375 A376 T474 I475 F476T370-A372 PolarHBondContact O-N 3Å; T370-A372 PolarHBondContact OG1-N 3.04Å; A372-I374 PolarHBondContact O-N 3.46Å; A372-R375 PolarHBondContact O-N 3.13Å; A372-A376 WeakPolarHBondContact O-CB 3.39Å; A372-A376 PolarHBondContact O-N 3.35Å; A372-T474 HydrophobicContact CB-CG2 3.61Å; A372-I475 WeakPolarHBondContact CB-O 3.34Å; A372-F476 HydrophobicContact CB-CD1 3.39Å; A372-F476 HydrophobicContact CB-CE1 3.56Å; A372-F476 HydrophobicContact CB-CG 4.03Å; A372-F476 HydrophobicContact CB-CZ 4.31Å
373D71.5Confident64.7Low11 Ų1155 Ų556%0.05928%0.284CS..Hα-helixtrans-59.5-41.1176-67.2-44.6000110.7L362 K366 I369 T370 D371 A376 L377L362-D373 HydrophobicContact CD2-CB 3.69Å; K366-D373 WeakPolarHBondContact CD-OD2 3.44Å; K366-D373 WeakPolarHBondContact CE-OD2 3.42Å; K366-D373 IonicContact NZ-OD1 3.23Å; K366-D373 PolarHBondContact NZ-OD1 2.73Å; K366-D373 IonicContact NZ-OD2 3.35Å; K366-D373 PolarHBondContact NZ-OD2 3.32Å; I369-D373 WeakPolarHBondContact CA-OD2 3.13Å; I369-D373 HydrophobicContact CG2-CB 3.78Å; T370-D373 PolarHBondContact N-OD2 3.09Å; T370-D373 WeakPolarHBondContact O-CB 3.22Å; T370-D373 PolarHBondContact O-N 2.77Å; T370-D373 VanDerWaalsContact O-N 3.09Å; T370-D373 PolarHBondContact OG1-N 2.75Å; T370-D373 PolarHBondContact OG1-OD2 2.8Å; D371-D373 PolarHBondContact O-N 2.95Å; D373-A376 PolarHBondContact O-N 2.68Å; D373-L377 VanDerWaalsContact O-CG 3.24Å; D373-L377 WeakPolarHBondContact O-CG 3.32Å; D373-L377 PolarHBondContact O-N 3.33Å
374I74Confident62.9Low1 Ų161 Ų611%0.00531%0.31CS..Hα-helixtrans-65.5-44.4177.4-56.4-63.6000110.9L327 F336 L340 L343 L345 F359 I369 T370 D371 A372 A376 L377 V378L327-I374 HydrophobicContact CD1-CD1 3.41Å; L327-I374 VanDerWaalsContact CD1-CD1 3.41Å; L327-I374 HydrophobicContact CD1-CG1 3.94Å; F336-I374 HydrophobicContact CD2-CD1 4.15Å; F336-I374 HydrophobicContact CE2-CD1 3.82Å; F336-I374 HydrophobicContact CE2-CG2 4.2Å; L340-I374 HydrophobicContact CD2-CG2 3.5Å; L340-I374 VanDerWaalsContact CD2-CG2 3.5Å; L343-I374 HydrophobicContact CD1-CB 3.97Å; L343-I374 HydrophobicContact CD1-CG2 3.91Å; L345-I374 HydrophobicContact CD1-CG2 4.05Å; F359-I374 HydrophobicContact CD2-CD1 3.73Å; F359-I374 HydrophobicContact CE2-CD1 4Å; I369-I374 HydrophobicContact CG2-CD1 3.54Å; I369-I374 HydrophobicContact CG2-CG1 3.94Å; T370-I374 PolarHBondContact O-N 2.75Å; D371-I374 WeakPolarHBondContact O-CB 3.33Å; D371-I374 PolarHBondContact O-N 3.42Å; A372-I374 PolarHBondContact O-N 3.46Å; I374-A376 VanDerWaalsContact C-N 3.35Å; I374-A376 PolarHBondContact O-N 3.32Å; I374-L377 HydrophobicContact CD1-CD1 4.31Å; I374-L377 PolarHBondContact O-N 3Å; I374-V378 WeakPolarHBondContact O-CG2 3.4Å; I374-V378 PolarHBondContact O-N 3.18Å
375R65.8Low61.3Low30 Ų3059.8 Ų59.811%0.11330%0.304CS..Hα-helixtrans-59.4-43.7175-64.1-170.7-173-79.5-0.2111.8L343 L345 D371 A372 L377 V378 A379 T474L343-R375 PolarHBondContact O-NH1 2.92Å; L343-R375 PolarHBondContact O-NH2 2.81Å; L345-R375 HydrophobicContact CD1-CG 4Å; L345-R375 HydrophobicContact CD2-CG 4.06Å; L345-R375 HydrophobicContact CG-CG 4.49Å; D371-R375 WeakPolarHBondContact O-CG 3.32Å; D371-R375 PolarHBondContact O-N 3.33Å; A372-R375 PolarHBondContact O-N 3.13Å; R375-L377 PolarHBondContact O-N 3.4Å; R375-V378 PolarHBondContact O-N 3.28Å; R375-A379 WeakPolarHBondContact O-CB 3.26Å; R375-A379 PolarHBondContact O-N 3.39Å; R375-T474 WeakPolarHBondContact CD-OG1 3.34Å
376A63.9Low60Low1 Ų156.7 Ų56.71%0.00830%0.301CS..Hα-helixtrans-65.1-37.217700000113.5A372 D373 I374 V378 A379 G380 T381 I383 I508A372-A376 WeakPolarHBondContact O-CB 3.39Å; A372-A376 PolarHBondContact O-N 3.35Å; D373-A376 PolarHBondContact O-N 2.68Å; I374-A376 VanDerWaalsContact C-N 3.35Å; I374-A376 PolarHBondContact O-N 3.32Å; A376-V378 VanDerWaalsContact C-N 3.33Å; A376-V378 PolarHBondContact O-N 3.41Å; A376-A379 WeakPolarHBondContact O-CB 3.19Å; A376-A379 PolarHBondContact O-N 2.89Å; A376-G380 PolarHBondContact O-N 3.43Å; A376-T381 PolarHBondContact O-N 3.43Å; A376-T381 PolarHBondContact O-OG1 3.36Å; A376-I383 HydrophobicContact CB-CD1 3.61Å; A376-I383 HydrophobicContact CB-CG1 3.99Å; A376-I508 HydrophobicContact CB-CB 4.5Å; A376-I508 HydrophobicContact CB-CG1 4.14Å; A376-I508 HydrophobicContact CB-CG2 3.79Å
377L71.3Confident59.4Low16 Ų1662 Ų628%0.08433%0.327CS..Hα-helixtrans-61.6-41.3175.2-76.1165.1000112.3L355 K358 F359 L362 D373 I374 R375 G380L355-L377 WeakPolarHBondContact CD2-O 3.46Å; K358-L377 HydrophobicContact CB-CD2 3.52Å; F359-L377 HydrophobicContact CB-CD1 3.87Å; F359-L377 HydrophobicContact CD2-CD1 4.21Å; L362-L377 HydrophobicContact CB-CD1 4.41Å; L362-L377 HydrophobicContact CB-CD2 4.34Å; L362-L377 HydrophobicContact CD2-CD1 3.7Å; L362-L377 HydrophobicContact CD2-CD2 4.22Å; L362-L377 HydrophobicContact CD2-CG 3.95Å; D373-L377 VanDerWaalsContact O-CG 3.24Å; D373-L377 WeakPolarHBondContact O-CG 3.32Å; D373-L377 PolarHBondContact O-N 3.33Å; I374-L377 HydrophobicContact CD1-CD1 4.31Å; I374-L377 PolarHBondContact O-N 3Å; R375-L377 PolarHBondContact O-N 3.4Å; L377-G380 PolarHBondContact O-N 2.99Å
378V68.3Low59.8Low40 Ų4053.3 Ų53.324%0.24229%0.291CS..Hα-helixtrans-66.7-39.8175.8177.70000111.3L340 L345 L355 I374 R375 A376 G380L340-V378 HydrophobicContact CD2-CG2 3.51Å; L345-V378 HydrophobicContact CD1-CG2 3.99Å; L355-V378 HydrophobicContact CD1-CG2 4.22Å; L355-V378 HydrophobicContact CD2-CG2 4.37Å; I374-V378 WeakPolarHBondContact O-CG2 3.4Å; I374-V378 PolarHBondContact O-N 3.18Å; R375-V378 PolarHBondContact O-N 3.28Å; A376-V378 VanDerWaalsContact C-N 3.33Å; A376-V378 PolarHBondContact O-N 3.41Å; V378-G380 PolarHBondContact O-N 3.05Å
379A61.9Low60.5Low42 Ų4249.7 Ų49.735%0.34727%0.274SS..Hα-helixtrans-65.5-21.9176.100000115.1R375 A376R375-A379 WeakPolarHBondContact O-CB 3.26Å; R375-A379 PolarHBondContact O-N 3.39Å; A376-A379 WeakPolarHBondContact O-CB 3.19Å; A376-A379 PolarHBondContact O-N 2.89Å
380G54.3Low61.2Low43 Ų4353.5 Ų53.544%0.44329%0.291SS..THydrogen-bonded Turntrans84.415.7-177.400000115A376 L377 V378A376-G380 PolarHBondContact O-N 3.43Å; L377-G380 PolarHBondContact O-N 2.99Å; V378-G380 PolarHBondContact O-N 3.05Å
381T41.3Very low62.1Low23 Ų2354.1 Ų54.114%0.14129%0.293CS..  trans-82.5128.1176.7-2.50000111.9A376 I383 E507 I508A376-T381 PolarHBondContact O-N 3.43Å; A376-T381 PolarHBondContact O-OG1 3.36Å; T381-I383 PolarHBondContact O-N 3.21Å; T381-E507 WeakPolarHBondContact CB-O 3.49Å; T381-E507 HydrophobicContact CG2-CB 3.58Å; T381-E507 WeakPolarHBondContact CG2-O 3.45Å; T381-E507 VanDerWaalsContact OG1-C 3.3Å; T381-E507 PolarHBondContact OG1-O 3.35Å; T381-I508 HydrophobicContact CG2-CG1 3.94Å; T381-I508 VanDerWaalsContact OG1-CA 3.3Å; T381-I508 WeakPolarHBondContact OG1-CA 3.45Å; T381-I508 WeakPolarHBondContact OG1-CG1 3.44Å
382E37.8Very low63Low172 Ų17253.3 Ų53.380%0.80430%0.296SS*.  trans-79.2116.3157.9-74.9-171.2159.500108.5E384E382-E384 PolarHBondContact O-N 2.65Å
383I43.9Very low64.6Low49 Ų4956.7 Ų56.725%0.25131%0.314SS..  trans-80.367.8175.2-49.7179.2000108.6A376 T381 F499A376-I383 HydrophobicContact CB-CD1 3.61Å; A376-I383 HydrophobicContact CB-CG1 3.99Å; T381-I383 PolarHBondContact O-N 3.21Å; I383-F499 HydrophobicContact CG2-CD1 3.48Å; I383-F499 VanDerWaalsContact CG2-CD1 3.48Å; I383-F499 HydrophobicContact CG2-CE1 3.04Å; I383-F499 HydrophobicContact CG2-CZ 3.94Å
384E38Very low65.8Low131 Ų13157 Ų5761%0.61232%0.316SS*.  trans-118.7126156.4-76.4-176.9-174.200105.9K365 E382 P386 K502K365-E384 IonicContact NZ-OE1 2.61Å; E382-E384 PolarHBondContact O-N 2.65Å; E384-P386 VanDerWaalsContact O-CD 3.28Å; E384-P386 WeakPolarHBondContact O-CD 3.27Å; E384-K502 PolarHBondContact O-NZ 3.16Å
385N44.9Very low66.8Low65 Ų6562.4 Ų62.435%0.34834%0.339SS..  trans-114.666.5178.1-16319.1000111.5E387 G388N385-E387 PolarHBondContact O-N 2.93Å; N385-G388 PolarHBondContact OD1-N 3.12Å
386P46.1Very low68.2Low100 Ų10063.6 Ų63.665%0.64935%0.348SS*.SBendtrans-74.2-11.3170.428.5-30.1000113.2E384E384-P386 VanDerWaalsContact O-CD 3.28Å; E384-P386 WeakPolarHBondContact O-CD 3.27Å
387E54.3Low69.8Low176 Ų17666.3 Ų66.382%0.82236%0.364SS*.SBendtrans-105.3-5.7-170.3-61.2-166.9170.300115.3N385N385-E387 PolarHBondContact O-N 2.93Å
388G71.4Confident70.8Confident18 Ų1870.5 Ų70.519%0.18640%0.395CS..SBendtrans-91.1170.9-17900000115.5N385N385-G388 PolarHBondContact OD1-N 3.12Å
389F82.5Confident72Confident49 Ų4971 Ų7122%0.21540%0.396CS..  trans-65135.6165.4-80.2-93.7000110.4M410 V411 N412 E416 V418 F438F389-M410 HydrophobicContact CB-CB 4.3Å; F389-M410 HydrophobicContact CB-CE 4.02Å; F389-M410 HydrophobicContact CD1-CB 3.79Å; F389-M410 HydrophobicContact CG-CB 4.41Å; F389-V411 CarbonylContact C-O 3.55Å; F389-V411 VanDerWaalsContact CA-O 3.3Å; F389-V411 WeakPolarHBondContact CA-O 3.4Å; F389-N412 HydrophobicContact CD1-CB 3.89Å; F389-N412 HydrophobicContact CD2-CB 4.02Å; F389-N412 HydrophobicContact CE1-CB 3.91Å; F389-N412 HydrophobicContact CE2-CB 4.04Å; F389-N412 HydrophobicContact CG-CB 3.95Å; F389-N412 HydrophobicContact CZ-CB 3.98Å; F389-E416 HydrophobicContact CE1-CB 4.45Å; F389-E416 WeakPolarHBondContact CE1-O 3.33Å; F389-E416 HydrophobicContact CZ-CB 4.29Å; F389-E416 HydrophobicContact CZ-CG 4.25Å; F389-V418 HydrophobicContact CE1-CB 4.17Å; F389-V418 HydrophobicContact CE1-CG2 3.6Å; F389-V418 HydrophobicContact CZ-CG2 3.73Å; F389-F438 HydrophobicContact CB-CE1 3.89Å; F389-F438 HydrophobicContact CB-CZ 3.58Å; F389-F438 HydrophobicContact CD1-CE2 4.43Å; F389-F438 AromaticContact CD1-CZ 3.99Å; F389-F438 HydrophobicContact CD1-CZ 3.99Å; F389-F438 AromaticContact CD2-CZ 3.76Å; F389-F438 HydrophobicContact CD2-CZ 3.76Å; F389-F438 HydrophobicContact CE2-CZ 4.42Å; F389-F438 HydrophobicContact CG-CE1 4.3Å; F389-F438 HydrophobicContact CG-CE2 4.36Å; F389-F438 AromaticContact CG-CZ 3.51Å; F389-F438 HydrophobicContact CG-CZ 3.51Å
390H86Confident73.4Confident93 Ų9374.3 Ų74.343%0.43142%0.423SS..EExtended strand (participates in β ladder)trans-118.9167.4173.258.2-82.7000110.3G392 M410 V411H390-G392 PolarHBondContact O-N 3.23Å; H390-M410 WeakPolarHBondContact O-CA 3.45Å; H390-V411 PolarHBondContact CE1-O 3.23Å; H390-V411 PolarHBondContact N-O 3.46Å; H390-V411 PolarHBondContact ND1-O 2.89Å; H390-V411 PolarHBondContact O-N 3.34Å
391F92.1Very high75.1Confident26 Ų2677.4 Ų77.411%0.11443%0.43CS..EExtended strand (participates in β ladder)trans-64.6125.4175.6176.5-95000110.5D393 L394 V408 K487 A490 I491 V494F391-D393 WeakPolarHBondContact CE2-O 3.48Å; F391-L394 HydrophobicContact CE2-CB 3.9Å; F391-L394 HydrophobicContact CZ-CB 3.66Å; F391-V408 HydrophobicContact CD2-CG1 4.24Å; F391-V408 HydrophobicContact CE2-CG1 4.32Å; F391-K487 HydrophobicContact CE1-CB 4.26Å; F391-K487 HydrophobicContact CE1-CD 4.5Å; F391-K487 HydrophobicContact CE1-CG 4.42Å; F391-K487 HydrophobicContact CZ-CB 4.25Å; F391-K487 HydrophobicContact CZ-CG 4.15Å; F391-A490 HydrophobicContact CD2-CB 3.72Å; F391-A490 HydrophobicContact CE2-CB 3.45Å; F391-A490 VanDerWaalsContact CE2-CB 3.45Å; F391-A490 HydrophobicContact CZ-CB 4.1Å; F391-I491 HydrophobicContact CB-CG1 4Å; F391-I491 HydrophobicContact CD1-CD1 4.08Å; F391-I491 HydrophobicContact CD1-CG1 3.43Å; F391-I491 VanDerWaalsContact CD1-CG1 3.43Å; F391-I491 HydrophobicContact CE1-CD1 4.42Å; F391-I491 HydrophobicContact CE1-CG1 4.07Å; F391-I491 HydrophobicContact CG-CG1 3.8Å; F391-V494 HydrophobicContact CB-CG2 4.36Å
392G92.3Very high77.3Confident33 Ų3383.2 Ų83.234%0.3446%0.46SS..EExtended strand (participates in β ladder)trans-99-59.2175.100000112.6H390 L409H390-G392 PolarHBondContact O-N 3.23Å; G392-L409 WeakPolarHBondContact CA-O 3.4Å; G392-L409 PolarHBondContact N-O 3.49Å
393D94.4Very high80Confident72 Ų7276.6 Ų76.639%0.38543%0.431SS..EExtended strand (participates in β ladder)trans-156.8169.3-179.2-1568.6000112.3F391 L409 K487F391-D393 WeakPolarHBondContact CE2-O 3.48Å; D393-L409 HydrophobicContact CB-CB 4.19Å; D393-L409 HydrophobicContact CB-CD2 4.19Å; D393-L409 PolarHBondContact N-O 2.84Å; D393-L409 PolarHBondContact O-N 2.79Å; D393-K487 WeakPolarHBondContact OD1-CE 3.19Å; D393-K487 IonicContact OD1-NZ 3.89Å; D393-K487 PolarHBondContact OD1-NZ 2.62Å
394L96.5Very high82.4Confident18 Ų1874.8 Ų74.89%0.09442%0.423CS..EExtended strand (participates in β ladder)trans-137.5130179.6172.464.8000110.6F391 L396 A406 V408 I431 L486 K487F391-L394 HydrophobicContact CE2-CB 3.9Å; F391-L394 HydrophobicContact CZ-CB 3.66Å; L394-L396 HydrophobicContact CD1-CD2 4.12Å; L394-L396 HydrophobicContact CD1-CG 4.09Å; L394-L396 HydrophobicContact CD2-CD1 4.08Å; L394-L396 HydrophobicContact CD2-CG 4.28Å; L394-L396 HydrophobicContact CG-CD1 4.43Å; L394-L396 HydrophobicContact CG-CG 4.11Å; L394-A406 HydrophobicContact CD1-CB 4.33Å; L394-V408 HydrophobicContact CD1-CG2 4Å; L394-I431 HydrophobicContact CD1-CD1 4.32Å; L394-I431 HydrophobicContact CD1-CG1 3.75Å; L394-I431 HydrophobicContact CD2-CD1 3.58Å; L394-I431 HydrophobicContact CD2-CG1 3.97Å; L394-L486 HydrophobicContact CD2-CB 3.94Å; L394-K487 HydrophobicContact CB-CG 4.25Å; L394-K487 HydrophobicContact CD2-CG 4.36Å
395K96.3Very high85.2Confident114 Ų11469.6 Ų69.650%0.49640%0.4SS..EExtended strand (participates in β ladder)trans-121.6135.8166.6172.6168.3165.9-104.70110.3E407K395-E407 HydrophobicContact CB-CB 4.09Å; K395-E407 PolarHBondContact N-O 3.39Å; K395-E407 IonicContact NZ-OE1 2.71Å; K395-E407 PolarHBondContact NZ-OE1 2.83Å; K395-E407 IonicContact NZ-OE2 3.09Å; K395-E407 PolarHBondContact NZ-OE2 3.49Å; K395-E407 PolarHBondContact O-N 2.64Å
396L95.5Very high87.7Confident55 Ų5566.5 Ų66.529%0.28838%0.383SS..EExtended strand (participates in β ladder)trans-122.8135.8-179.3-69.1166.8000110.2L394 V404 T405 A406 I431 L486L394-L396 HydrophobicContact CD1-CD2 4.12Å; L394-L396 HydrophobicContact CD1-CG 4.09Å; L394-L396 HydrophobicContact CD2-CD1 4.08Å; L394-L396 HydrophobicContact CD2-CG 4.28Å; L394-L396 HydrophobicContact CG-CD1 4.43Å; L394-L396 HydrophobicContact CG-CG 4.11Å; L396-V404 HydrophobicContact CB-CG1 4.38Å; L396-V404 HydrophobicContact CD2-CG1 3.74Å; L396-T405 WeakPolarHBondContact CA-O 3.37Å; L396-A406 HydrophobicContact CD2-CB 3.67Å; L396-I431 HydrophobicContact CD1-CD1 4.41Å; L396-I431 HydrophobicContact CD2-CD1 4.37Å; L396-I431 HydrophobicContact CD2-CG1 4.01Å; L396-L486 HydrophobicContact CD1-CB 4.39Å; L396-L486 HydrophobicContact CD1-CD1 3.34Å; L396-L486 HydrophobicContact CD1-CG 4.43Å
397T95.8Very high90.1Very high57 Ų5763.3 Ų63.335%0.3536%0.36SS..EExtended strand (participates in β ladder)trans-124.4117.8173.8-57.50000109V404 T405T397-V404 WeakPolarHBondContact O-CA 3.42Å; T397-T405 PolarHBondContact N-O 2.75Å; T397-T405 PolarHBondContact O-N 3.17Å
398S93.1Very high92.1Very high105 Ų10555 Ų5573%0.73432%0.321SS*.EExtended strand (participates in β ladder)trans-76.5124.4168.9-59.30000109.6
399N92.9Very high93.3Very high51 Ų5156.1 Ų56.127%0.27332%0.322SS..  trans-92.9162.3-179.2-58.1-48.3000111.1D401 D402 T403 T405N399-D401 VanDerWaalsContact CB-OD1 3.23Å; N399-D401 WeakPolarHBondContact CB-OD1 3.38Å; N399-D401 PolarHBondContact O-N 2.61Å; N399-D402 PolarHBondContact O-N 2.65Å; N399-T403 WeakPolarHBondContact CB-O 3.21Å; N399-T403 PolarHBondContact N-O 3.25Å; N399-T403 PolarHBondContact ND2-O 2.87Å; N399-T403 PolarHBondContact ND2-OG1 2.9Å; N399-T405 PolarHBondContact ND2-OG1 3.02Å; N399-T405 PolarHBondContact OD1-OG1 2.99Å
400A91.7Very high93.8Very high111 Ų11153.8 Ų53.892%0.91731%0.312SS*.THydrogen-bonded Turntrans-71.2-11-178.800000114.4
401D90.9Very high94Very high107 Ų10750.5 Ų50.557%0.57230%0.299SS*.THydrogen-bonded Turntrans-99.720.417966.6-8.7000112.9N399 T403N399-D401 VanDerWaalsContact CB-OD1 3.23Å; N399-D401 WeakPolarHBondContact CB-OD1 3.38Å; N399-D401 PolarHBondContact O-N 2.61Å; D401-T403 PolarHBondContact O-N 2.89Å; D401-T403 WeakPolarHBondContact OD1-CB 3.37Å; D401-T403 WeakPolarHBondContact OD1-CG2 3.27Å; D401-T403 PolarHBondContact OD1-N 3.23Å; D401-T403 VanDerWaalsContact OD1-N 3.14Å; D401-T403 PolarHBondContact OD1-OG1 2.94Å
402D87.2Confident93.7Very high145 Ų14550.2 Ų50.278%0.77530%0.298SS*.SBendtrans63.79.4-176.3-56.6-42.6000115N399N399-D402 PolarHBondContact O-N 2.65Å
403T93.3Very high92.9Very high34 Ų3452.3 Ų52.321%0.20931%0.312CS..  trans-84.8159.3169.769.10000111.7N399 D401 G424N399-T403 WeakPolarHBondContact CB-O 3.21Å; N399-T403 PolarHBondContact N-O 3.25Å; N399-T403 PolarHBondContact ND2-O 2.87Å; N399-T403 PolarHBondContact ND2-OG1 2.9Å; D401-T403 PolarHBondContact O-N 2.89Å; D401-T403 WeakPolarHBondContact OD1-CB 3.37Å; D401-T403 WeakPolarHBondContact OD1-CG2 3.27Å; D401-T403 PolarHBondContact OD1-N 3.23Å; D401-T403 VanDerWaalsContact OD1-N 3.14Å; D401-T403 PolarHBondContact OD1-OG1 2.94Å; T403-G424 WeakPolarHBondContact CA-O 3.44Å; T403-G424 WeakPolarHBondContact CB-O 3.01Å
404V94.5Very high92.2Very high11 Ų1156.1 Ų56.17%0.06733%0.333CS..EExtended strand (participates in β ladder)trans-117.2131.4172.5-178.20000108.7L396 T397 N423 G424 A430L396-V404 HydrophobicContact CB-CG1 4.38Å; L396-V404 HydrophobicContact CD2-CG1 3.74Å; T397-V404 WeakPolarHBondContact O-CA 3.42Å; V404-N423 CarbonylContact O-C 3.53Å; V404-N423 VanDerWaalsContact O-CA 3.29Å; V404-N423 WeakPolarHBondContact O-CA 3.46Å; V404-G424 PolarHBondContact N-O 2.93Å; V404-G424 PolarHBondContact O-N 3.28Å; V404-A430 HydrophobicContact CB-CB 4.13Å; V404-A430 HydrophobicContact CG1-CB 4.17Å; V404-A430 WeakPolarHBondContact O-CB 3.49Å
405T97.3Very high91.5Very high22 Ų2257.7 Ų57.714%0.13535%0.353CS..EExtended strand (participates in β ladder)trans-94.7126.5168.8-52.70000108.6L396 T397 N399 I421 N423L396-T405 WeakPolarHBondContact CA-O 3.37Å; T397-T405 PolarHBondContact N-O 2.75Å; T397-T405 PolarHBondContact O-N 3.17Å; N399-T405 PolarHBondContact ND2-OG1 3.02Å; N399-T405 PolarHBondContact OD1-OG1 2.99Å; T405-I421 HydrophobicContact CG2-CG2 3.59Å; T405-N423 WeakPolarHBondContact CG2-OD1 3.37Å; T405-N423 PolarHBondContact OG1-OD1 3.17Å
406A97.3Very high91.1Very high0 Ų057.6 Ų57.60%036%0.355CS..EExtended strand (participates in β ladder)trans-107.412917100000110.4L394 L396 V408 I421 A422 A430 I431L394-A406 HydrophobicContact CD1-CB 4.33Å; L396-A406 HydrophobicContact CD2-CB 3.67Å; A406-V408 HydrophobicContact CB-CG2 4.5Å; A406-I421 VanDerWaalsContact O-CA 3.3Å; A406-I421 WeakPolarHBondContact O-CA 3.49Å; A406-A422 PolarHBondContact N-O 2.78Å; A406-A422 PolarHBondContact O-N 3.47Å; A406-A430 VanDerWaalsContact CB-C 3.47Å; A406-A430 HydrophobicContact CB-CB 3.76Å; A406-I431 HydrophobicContact CB-CG1 4.09Å
407E97.6Very high90.9Very high32 Ų3261.4 Ų61.415%0.1537%0.371CS..EExtended strand (participates in β ladder)trans-106.5103.7168.7-70.4160.5-95.300106.6K395 I421K395-E407 HydrophobicContact CB-CB 4.09Å; K395-E407 PolarHBondContact N-O 3.39Å; K395-E407 IonicContact NZ-OE1 2.71Å; K395-E407 PolarHBondContact NZ-OE1 2.83Å; K395-E407 IonicContact NZ-OE2 3.09Å; K395-E407 PolarHBondContact NZ-OE2 3.49Å; K395-E407 PolarHBondContact O-N 2.64Å; E407-I421 HydrophobicContact CG-CD1 3.97Å; E407-I421 HydrophobicContact CG-CG1 3.9Å; E407-I421 HydrophobicContact CG-CG2 4.26Å
408V96.3Very high90.8Very high1 Ų160.8 Ų60.81%0.00637%0.367CS..EExtended strand (participates in β ladder)trans-102.3121.9-179.5-179.60000109F391 L394 A406 M410 V420 I431 A434 V435F391-V408 HydrophobicContact CD2-CG1 4.24Å; F391-V408 HydrophobicContact CE2-CG1 4.32Å; L394-V408 HydrophobicContact CD1-CG2 4Å; A406-V408 HydrophobicContact CB-CG2 4.5Å; V408-M410 HydrophobicContact CG1-SD 3.98Å; V408-V420 PolarHBondContact N-O 2.92Å; V408-V420 PolarHBondContact O-N 3.21Å; V408-I431 HydrophobicContact CG2-CG2 4.36Å; V408-A434 HydrophobicContact CB-CB 4.2Å; V408-A434 HydrophobicContact CG2-CB 3.64Å; V408-V435 HydrophobicContact CG1-CG2 4.41Å
409L96.2Very high90.9Very high42 Ų4261.3 Ų61.322%0.2236%0.358CS..EExtended strand (participates in β ladder)trans-93.2123175.6-17768.7000109.6G392 D393 V411 E417G392-L409 WeakPolarHBondContact CA-O 3.4Å; G392-L409 PolarHBondContact N-O 3.49Å; D393-L409 HydrophobicContact CB-CB 4.19Å; D393-L409 HydrophobicContact CB-CD2 4.19Å; D393-L409 PolarHBondContact N-O 2.84Å; D393-L409 PolarHBondContact O-N 2.79Å; L409-V411 HydrophobicContact CD2-CG2 4.39Å; L409-V411 HydrophobicContact CG-CG2 4.24Å; L409-E417 HydrophobicContact CD1-CB 3.98Å; L409-E417 HydrophobicContact CD1-CG 4.42Å
410M93.3Very high91Very high0 Ų059.5 Ų59.50%035%0.348CS..EExtended strand (participates in β ladder)trans-106.4135174.9-59.7-63-64.400109.2F389 H390 V408 E417 V418 F438 F439 V494F389-M410 HydrophobicContact CB-CB 4.3Å; F389-M410 HydrophobicContact CB-CE 4.02Å; F389-M410 HydrophobicContact CD1-CB 3.79Å; F389-M410 HydrophobicContact CG-CB 4.41Å; H390-M410 WeakPolarHBondContact O-CA 3.45Å; V408-M410 HydrophobicContact CG1-SD 3.98Å; M410-E417 WeakPolarHBondContact O-CA 3.37Å; M410-V418 HydrophobicContact CB-CB 4.46Å; M410-V418 PolarHBondContact N-O 3.46Å; M410-V418 PolarHBondContact O-N 3.18Å; M410-F438 HydrophobicContact CB-CD2 4.22Å; M410-F438 HydrophobicContact CB-CE2 3.79Å; M410-F438 HydrophobicContact CB-CZ 3.98Å; M410-F438 HydrophobicContact CE-CD1 3.89Å; M410-F438 HydrophobicContact CE-CE1 3.73Å; M410-F438 HydrophobicContact CE-CZ 4.25Å; M410-F438 HydrophobicContact CG-CD1 4.16Å; M410-F438 HydrophobicContact CG-CD2 3.73Å; M410-F438 HydrophobicContact CG-CE1 4.25Å; M410-F438 HydrophobicContact CG-CE2 3.81Å; M410-F438 HydrophobicContact CG-CG 3.9Å; M410-F438 HydrophobicContact CG-CZ 4.09Å; M410-F439 HydrophobicContact CE-CE2 4.35Å; M410-F439 HydrophobicContact CE-CZ 4.4Å; M410-V494 HydrophobicContact CE-CG1 3.71Å; M410-V494 HydrophobicContact CE-CG2 4.1Å; M410-V494 HydrophobicContact SD-CG2 3.96Å
411V89.7Confident91.3Very high25 Ų2557.8 Ų57.815%0.15232%0.323CS..EExtended strand (participates in β ladder)trans-126.5137-177.9-171.90000109.9F389 H390 L409 E416 E417F389-V411 CarbonylContact C-O 3.55Å; F389-V411 VanDerWaalsContact CA-O 3.3Å; F389-V411 WeakPolarHBondContact CA-O 3.4Å; H390-V411 PolarHBondContact CE1-O 3.23Å; H390-V411 PolarHBondContact N-O 3.46Å; H390-V411 PolarHBondContact ND1-O 2.89Å; H390-V411 PolarHBondContact O-N 3.34Å; L409-V411 HydrophobicContact CD2-CG2 4.39Å; L409-V411 HydrophobicContact CG-CG2 4.24Å; V411-E416 WeakPolarHBondContact CA-O 3.38Å; V411-E417 HydrophobicContact CG2-CG 4.25Å
412N85.9Confident91.5Very high19 Ų1953.4 Ų53.410%0.10230%0.302CS..  trans-104.3177172.97311.7000112.3F389 D414 G415 E416F389-N412 HydrophobicContact CD1-CB 3.89Å; F389-N412 HydrophobicContact CD2-CB 4.02Å; F389-N412 HydrophobicContact CE1-CB 3.91Å; F389-N412 HydrophobicContact CE2-CB 4.04Å; F389-N412 HydrophobicContact CG-CB 3.95Å; F389-N412 HydrophobicContact CZ-CB 3.98Å; N412-D414 PolarHBondContact O-N 3.41Å; N412-D414 PolarHBondContact OD1-N 3.11Å; N412-G415 PolarHBondContact O-N 3.05Å; N412-G415 VanDerWaalsContact O-N 3.11Å; N412-G415 PolarHBondContact OD1-N 3.36Å; N412-G415 VanDerWaalsContact OD1-N 3.15Å; N412-E416 PolarHBondContact N-O 2.88Å; N412-E416 VanDerWaalsContact N-O 3.13Å; N412-E416 VanDerWaalsContact ND2-CB 3.33Å; N412-E416 WeakPolarHBondContact ND2-CB 3.28Å; N412-E416 PolarHBondContact ND2-OE2 3.1Å; N412-E416 VanDerWaalsContact ND2-OE2 3.11Å; N412-E416 VanDerWaalsContact OD1-CB 3.31Å; N412-E416 WeakPolarHBondContact OD1-CB 3.27Å; N412-E416 PolarHBondContact OD1-N 3.45Å
413A76.1Confident92Very high77 Ų7751 Ų5164%0.63629%0.289SS*.THydrogen-bonded Turntrans-64.2-24.2-179.100000113.9G415A413-G415 VanDerWaalsContact C-N 3.26Å; A413-G415 PolarHBondContact O-N 3.25Å
414D79.9Confident92Very high153 Ų15349.7 Ų49.782%0.81828%0.282SS*.THydrogen-bonded Turntrans-83.1-2.3177.6-65.8-40.5000112.8N412 E416N412-D414 PolarHBondContact O-N 3.41Å; N412-D414 PolarHBondContact OD1-N 3.11Å; D414-E416 VanDerWaalsContact C-N 3.33Å
415G80.4Confident91.8Very high50 Ų5057.5 Ų57.552%0.51532%0.315SS..  trans77.616.5-17700000113.8N412 A413N412-G415 PolarHBondContact O-N 3.05Å; N412-G415 VanDerWaalsContact O-N 3.11Å; N412-G415 PolarHBondContact OD1-N 3.36Å; N412-G415 VanDerWaalsContact OD1-N 3.15Å; A413-G415 VanDerWaalsContact C-N 3.26Å; A413-G415 PolarHBondContact O-N 3.25Å
416E88.3Confident91.4Very high113 Ų11357.7 Ų57.753%0.52832%0.322SS..  trans-69.9130169.1-166.9-178.7-179.300109.5F389 V411 N412 D414F389-E416 HydrophobicContact CE1-CB 4.45Å; F389-E416 WeakPolarHBondContact CE1-O 3.33Å; F389-E416 HydrophobicContact CZ-CB 4.29Å; F389-E416 HydrophobicContact CZ-CG 4.25Å; V411-E416 WeakPolarHBondContact CA-O 3.38Å; N412-E416 PolarHBondContact N-O 2.88Å; N412-E416 VanDerWaalsContact N-O 3.13Å; N412-E416 VanDerWaalsContact ND2-CB 3.33Å; N412-E416 WeakPolarHBondContact ND2-CB 3.28Å; N412-E416 PolarHBondContact ND2-OE2 3.1Å; N412-E416 VanDerWaalsContact ND2-OE2 3.11Å; N412-E416 VanDerWaalsContact OD1-CB 3.31Å; N412-E416 WeakPolarHBondContact OD1-CB 3.27Å; N412-E416 PolarHBondContact OD1-N 3.45Å; D414-E416 VanDerWaalsContact C-N 3.33Å
417E92Very high91.3Very high135 Ų13559.5 Ų59.563%0.63134%0.335SS*.EExtended strand (participates in β ladder)trans-110.7126-179.2-71.8-175.1-179.200109.9L409 M410 V411L409-E417 HydrophobicContact CD1-CB 3.98Å; L409-E417 HydrophobicContact CD1-CG 4.42Å; M410-E417 WeakPolarHBondContact O-CA 3.37Å; V411-E417 HydrophobicContact CG2-CG 4.25Å
418V93.1Very high91.1Very high44 Ų4460.5 Ų60.527%0.26734%0.342SS..EExtended strand (participates in β ladder)trans-123.4117.2176.8179.70000109.3F389 M410 V420 F438F389-V418 HydrophobicContact CE1-CB 4.17Å; F389-V418 HydrophobicContact CE1-CG2 3.6Å; F389-V418 HydrophobicContact CZ-CG2 3.73Å; M410-V418 HydrophobicContact CB-CB 4.46Å; M410-V418 PolarHBondContact N-O 3.46Å; M410-V418 PolarHBondContact O-N 3.18Å; V418-V420 HydrophobicContact CG1-CG2 4.12Å; V418-F438 HydrophobicContact CB-CE2 4.05Å; V418-F438 HydrophobicContact CG1-CD2 4.11Å; V418-F438 HydrophobicContact CG1-CE2 3.89Å
419E95.4Very high90.9Very high115 Ų11564.5 Ų64.554%0.53736%0.361SS..EExtended strand (participates in β ladder)trans-93.6127.1175.9-173.2175.5-154.700110.7I421E419-I421 HydrophobicContact CG-CG1 4.42Å
420V95.3Very high90.9Very high13 Ų1362.5 Ų62.58%0.07935%0.351CS..EExtended strand (participates in β ladder)trans-121126.6177.7-172.30000110.7V408 V418 A434 K437 F438V408-V420 PolarHBondContact N-O 2.92Å; V408-V420 PolarHBondContact O-N 3.21Å; V418-V420 HydrophobicContact CG1-CG2 4.12Å; V420-A434 HydrophobicContact CG1-CB 4.35Å; V420-A434 VanDerWaalsContact CG1-O 3.23Å; V420-A434 WeakPolarHBondContact CG1-O 3.31Å; V420-K437 HydrophobicContact CG1-CB 4.03Å; V420-K437 HydrophobicContact CG1-CD 3.82Å; V420-K437 HydrophobicContact CG1-CG 3.89Å; V420-F438 HydrophobicContact CG2-CB 3.89Å; V420-F438 HydrophobicContact CG2-CD2 3.67Å; V420-F438 HydrophobicContact CG2-CG 4.24Å
421I96.8Very high91.1Very high76 Ų7662.6 Ų62.639%0.3935%0.351SS..EExtended strand (participates in β ladder)trans-111.9130.5-177.4-47.8-176000110.1T405 A406 E407 E419 K437T405-I421 HydrophobicContact CG2-CG2 3.59Å; A406-I421 VanDerWaalsContact O-CA 3.3Å; A406-I421 WeakPolarHBondContact O-CA 3.49Å; E407-I421 HydrophobicContact CG-CD1 3.97Å; E407-I421 HydrophobicContact CG-CG1 3.9Å; E407-I421 HydrophobicContact CG-CG2 4.26Å; E419-I421 HydrophobicContact CG-CG1 4.42Å; I421-K437 PolarHBondContact O-NZ 3.34Å
422A96.8Very high91.4Very high15 Ų1562 Ų6212%0.12435%0.346CS..EExtended strand (participates in β ladder)trans-146.5160.5171.100000112.2A406 N433 A434A406-A422 PolarHBondContact N-O 2.78Å; A406-A422 PolarHBondContact O-N 3.47Å; A422-N433 HydrophobicContact CB-CB 3.79Å; A422-A434 HydrophobicContact CB-CB 3.77Å
423N96Very high91.8Very high93 Ų9363.9 Ų63.950%0.49736%0.356SS..EExtended strand (participates in β ladder)trans-107.4154.5176.5-62.1-26.1000110.4V404 T405 N433V404-N423 CarbonylContact O-C 3.53Å; V404-N423 VanDerWaalsContact O-CA 3.29Å; V404-N423 WeakPolarHBondContact O-CA 3.46Å; T405-N423 WeakPolarHBondContact CG2-OD1 3.37Å; T405-N423 PolarHBondContact OG1-OD1 3.17Å; N423-N433 PolarHBondContact O-ND2 3.31Å
424G93.2Very high92.8Very high7 Ų760.2 Ų60.27%0.07233%0.326CS..EExtended strand (participates in β ladder)trans-151.4170.4171.700000111.5T403 V404 G426T403-G424 WeakPolarHBondContact CA-O 3.44Å; T403-G424 WeakPolarHBondContact CB-O 3.01Å; V404-G424 PolarHBondContact N-O 2.93Å; V404-G424 PolarHBondContact O-N 3.28Å; G424-G426 PolarHBondContact O-N 3.22Å
425K90.6Very high93.5Very high175 Ų17552.9 Ų52.976%0.76129%0.287SS*.SBendtrans-78.9-7.4175.4-56.5177.2178.7173.30112.7E429K425-E429 WeakPolarHBondContact CA-OE2 3.39Å; K425-E429 WeakPolarHBondContact CB-OE2 3.2Å; K425-E429 PolarHBondContact N-OE2 2.54Å
426G90.2Very high94.1Very high26 Ų2652.3 Ų52.327%0.26827%0.272SS..SBendtrans-157.3168.9173.200000110.7G424 V428 E429 A430G424-G426 PolarHBondContact O-N 3.22Å; G426-V428 PolarHBondContact O-N 2.93Å; G426-E429 PolarHBondContact O-N 2.71Å; G426-A430 WeakPolarHBondContact O-CB 3.44Å; G426-A430 PolarHBondContact O-N 3.49Å
427S93.9Very high94.4Very high39 Ų3953.2 Ų53.227%0.27327%0.274SS..Hα-helixtrans-58.3-46.2-173.3-49.50000113E429 A430 I431S427-E429 PolarHBondContact O-N 3.09Å; S427-A430 PolarHBondContact O-N 2.83Å; S427-I431 VanDerWaalsContact O-CD1 3.26Å; S427-I431 WeakPolarHBondContact O-CD1 3.5Å; S427-I431 WeakPolarHBondContact O-CG1 3.3Å; S427-I431 PolarHBondContact O-N 2.8Å
428V93.3Very high94.5Very high52 Ų5249 Ų4932%0.31525%0.254SS..Hα-helixtrans-62.2-46.2179.2178.90000111.2G426 A430 I431 Y432 Y448 L486G426-V428 PolarHBondContact O-N 2.93Å; V428-A430 PolarHBondContact O-N 3.15Å; V428-I431 PolarHBondContact O-N 3.12Å; V428-Y432 HydrophobicContact CG1-CD1 4.28Å; V428-Y432 HydrophobicContact CG1-CD2 4.05Å; V428-Y432 HydrophobicContact CG1-CE1 4.04Å; V428-Y432 HydrophobicContact CG1-CE2 3.78Å; V428-Y432 HydrophobicContact CG1-CG 4.29Å; V428-Y432 WeakPolarHBondContact O-CB 3.08Å; V428-Y432 WeakPolarHBondContact O-CD1 3.37Å; V428-Y432 PolarHBondContact O-N 3.39Å; V428-Y448 HydrophobicContact CG1-CE2 4.48Å; V428-L486 HydrophobicContact CG2-CD2 4.19Å
429E93.7Very high94.4Very high85 Ų8547.7 Ų47.740%0.39724%0.244SC..Hα-helixtrans-62.4-42.7178.2-173.1-174.9-176.200111.4K425 G426 S427 Y432 N433K425-E429 WeakPolarHBondContact CA-OE2 3.39Å; K425-E429 WeakPolarHBondContact CB-OE2 3.2Å; K425-E429 PolarHBondContact N-OE2 2.54Å; G426-E429 PolarHBondContact O-N 2.71Å; S427-E429 PolarHBondContact O-N 3.09Å; E429-Y432 PolarHBondContact O-N 2.96Å; E429-N433 VanDerWaalsContact O-CB 3.28Å; E429-N433 WeakPolarHBondContact O-CB 3.02Å; E429-N433 PolarHBondContact O-N 2.78Å; E429-N433 PolarHBondContact O-ND2 3.4Å; E429-N433 PolarHBondContact O-OD1 3.33Å
430A96.1Very high94.1Very high0 Ų049.1 Ų49.10%026%0.256CS..Hα-helixtrans-62.7-44.7178.300000112V404 A406 G426 S427 V428 A434V404-A430 HydrophobicContact CB-CB 4.13Å; V404-A430 HydrophobicContact CG1-CB 4.17Å; V404-A430 WeakPolarHBondContact O-CB 3.49Å; A406-A430 VanDerWaalsContact CB-C 3.47Å; A406-A430 HydrophobicContact CB-CB 3.76Å; G426-A430 WeakPolarHBondContact O-CB 3.44Å; G426-A430 PolarHBondContact O-N 3.49Å; S427-A430 PolarHBondContact O-N 2.83Å; V428-A430 PolarHBondContact O-N 3.15Å; A430-A434 PolarHBondContact O-N 2.89Å; A430-A434 VanDerWaalsContact O-N 3.09Å
431I96.7Very high93.7Very high2 Ų249.6 Ų49.61%0.0126%0.257CS..Hα-helixtrans-60.4-49.3175.7-64.6160000109.8L394 L396 A406 V408 S427 V428 N433 A434 V435 L486 A490L394-I431 HydrophobicContact CD1-CD1 4.32Å; L394-I431 HydrophobicContact CD1-CG1 3.75Å; L394-I431 HydrophobicContact CD2-CD1 3.58Å; L394-I431 HydrophobicContact CD2-CG1 3.97Å; L396-I431 HydrophobicContact CD1-CD1 4.41Å; L396-I431 HydrophobicContact CD2-CD1 4.37Å; L396-I431 HydrophobicContact CD2-CG1 4.01Å; A406-I431 HydrophobicContact CB-CG1 4.09Å; V408-I431 HydrophobicContact CG2-CG2 4.36Å; S427-I431 VanDerWaalsContact O-CD1 3.26Å; S427-I431 WeakPolarHBondContact O-CD1 3.5Å; S427-I431 WeakPolarHBondContact O-CG1 3.3Å; S427-I431 PolarHBondContact O-N 2.8Å; V428-I431 PolarHBondContact O-N 3.12Å; I431-N433 PolarHBondContact O-N 3.43Å; I431-A434 WeakPolarHBondContact O-CB 3.28Å; I431-A434 PolarHBondContact O-N 2.99Å; I431-A434 VanDerWaalsContact O-N 3.12Å; I431-V435 HydrophobicContact CG2-CG2 4.46Å; I431-V435 WeakPolarHBondContact O-CG2 3.41Å; I431-V435 PolarHBondContact O-N 2.92Å; I431-L486 HydrophobicContact CD1-CB 3.94Å; I431-L486 HydrophobicContact CD1-CD2 4.4Å; I431-A490 HydrophobicContact CG2-CB 3.63Å
432Y95.3Very high93.2Very high13 Ų1349.9 Ų49.95%0.05126%0.263CS..Hα-helixtrans-68.4-38.2-175-72.712.1000110.9V428 E429 A434 V435 D436 L445 Y448 V465 G489 Y493V428-Y432 HydrophobicContact CG1-CD1 4.28Å; V428-Y432 HydrophobicContact CG1-CD2 4.05Å; V428-Y432 HydrophobicContact CG1-CE1 4.04Å; V428-Y432 HydrophobicContact CG1-CE2 3.78Å; V428-Y432 HydrophobicContact CG1-CG 4.29Å; V428-Y432 WeakPolarHBondContact O-CB 3.08Å; V428-Y432 WeakPolarHBondContact O-CD1 3.37Å; V428-Y432 PolarHBondContact O-N 3.39Å; E429-Y432 PolarHBondContact O-N 2.96Å; Y432-A434 VanDerWaalsContact C-N 3.28Å; Y432-A434 PolarHBondContact O-N 3.31Å; Y432-V435 PolarHBondContact O-N 2.98Å; Y432-D436 WeakPolarHBondContact O-CB 3.49Å; Y432-D436 PolarHBondContact O-N 3.23Å; Y432-L445 HydrophobicContact CD2-CD2 4.29Å; Y432-L445 HydrophobicContact CE2-CD1 4.11Å; Y432-L445 HydrophobicContact CE2-CD2 3.82Å; Y432-Y448 WeakPolarHBondContact OH-CD2 3.39Å; Y432-V465 WeakPolarHBondContact OH-CG1 3.38Å; Y432-G489 PolarHBondContact OH-O 3.46Å; Y432-Y493 AromaticContact CD1-CD1 3.48Å; Y432-Y493 HydrophobicContact CD1-CD1 3.48Å; Y432-Y493 VanDerWaalsContact CD1-CD1 3.48Å; Y432-Y493 HydrophobicContact CD1-CD2 4.15Å; Y432-Y493 HydrophobicContact CD1-CE1 4.01Å; Y432-Y493 AromaticContact CD1-CG 3.57Å; Y432-Y493 HydrophobicContact CD1-CG 3.57Å; Y432-Y493 HydrophobicContact CD2-CD1 4.03Å; Y432-Y493 AromaticContact CD2-CD2 3.61Å; Y432-Y493 HydrophobicContact CD2-CD2 3.61Å; Y432-Y493 AromaticContact CD2-CE1 3.92Å; Y432-Y493 HydrophobicContact CD2-CE1 3.92Å; Y432-Y493 AromaticContact CD2-CE2 3.46Å; Y432-Y493 HydrophobicContact CD2-CE2 3.46Å; Y432-Y493 VanDerWaalsContact CD2-CE2 3.46Å; Y432-Y493 AromaticContact CD2-CG 3.89Å; Y432-Y493 HydrophobicContact CD2-CG 3.89Å; Y432-Y493 AromaticContact CD2-CZ 3.65Å; Y432-Y493 AromaticContact CE1-CD1 3.92Å; Y432-Y493 HydrophobicContact CE1-CD1 3.92Å; Y432-Y493 AromaticContact CE1-CD2 3.95Å; Y432-Y493 HydrophobicContact CE1-CD2 3.95Å; Y432-Y493 AromaticContact CE1-CG 3.49Å; Y432-Y493 HydrophobicContact CE1-CG 3.49Å; Y432-Y493 VanDerWaalsContact CE1-CG 3.49Å; Y432-Y493 HydrophobicContact CE2-CD1 4.41Å; Y432-Y493 AromaticContact CE2-CD2 3.37Å; Y432-Y493 HydrophobicContact CE2-CD2 3.37Å; Y432-Y493 AromaticContact CE2-CE2 3.63Å; Y432-Y493 HydrophobicContact CE2-CE2 3.63Å; Y432-Y493 AromaticContact CE2-CG 3.81Å; Y432-Y493 HydrophobicContact CE2-CG 3.81Å; Y432-Y493 AromaticContact CG-CD1 3.54Å; Y432-Y493 HydrophobicContact CG-CD1 3.54Å; Y432-Y493 HydrophobicContact CG-CD2 4Å; Y432-Y493 AromaticContact CG-CE1 3.56Å; Y432-Y493 HydrophobicContact CG-CE1 3.56Å; Y432-Y493 HydrophobicContact CG-CE2 4Å; Y432-Y493 AromaticContact CG-CG 3.78Å; Y432-Y493 HydrophobicContact CG-CG 3.78Å; Y432-Y493 AromaticContact CG-CZ 3.81Å; Y432-Y493 AromaticContact CZ-CD2 3.56Å; Y432-Y493 AromaticContact CZ-CG 3.61Å
433N95.3Very high93Very high58 Ų5850.2 Ų50.231%0.3126%0.263SS..Hα-helixtrans-60.3-36.8171.7-70.9-15.5000112.4A422 N423 E429 I431 K437A422-N433 HydrophobicContact CB-CB 3.79Å; N423-N433 PolarHBondContact O-ND2 3.31Å; E429-N433 VanDerWaalsContact O-CB 3.28Å; E429-N433 WeakPolarHBondContact O-CB 3.02Å; E429-N433 PolarHBondContact O-N 2.78Å; E429-N433 PolarHBondContact O-ND2 3.4Å; E429-N433 PolarHBondContact O-OD1 3.33Å; I431-N433 PolarHBondContact O-N 3.43Å; N433-K437 WeakPolarHBondContact O-CB 3.46Å; N433-K437 PolarHBondContact O-N 2.92Å
434A96.2Very high92.8Very high0 Ų052 Ų520%026%0.263CS..Hα-helixtrans-70.2-41.8176.100000111.4V408 V420 A422 A430 I431 Y432 K437 F438V408-A434 HydrophobicContact CB-CB 4.2Å; V408-A434 HydrophobicContact CG2-CB 3.64Å; V420-A434 HydrophobicContact CG1-CB 4.35Å; V420-A434 VanDerWaalsContact CG1-O 3.23Å; V420-A434 WeakPolarHBondContact CG1-O 3.31Å; A422-A434 HydrophobicContact CB-CB 3.77Å; A430-A434 PolarHBondContact O-N 2.89Å; A430-A434 VanDerWaalsContact O-N 3.09Å; I431-A434 WeakPolarHBondContact O-CB 3.28Å; I431-A434 PolarHBondContact O-N 2.99Å; I431-A434 VanDerWaalsContact O-N 3.12Å; Y432-A434 VanDerWaalsContact C-N 3.28Å; Y432-A434 PolarHBondContact O-N 3.31Å; A434-K437 PolarHBondContact O-N 2.9Å; A434-F438 PolarHBondContact O-N 2.97Å
435V95Very high92.8Very high0 Ų055 Ų550%028%0.277CS..Hα-helixtrans-64.6-47.1175.4175.20000111.1V408 I431 Y432 K437 F438 F439 Y493 V494 N497V408-V435 HydrophobicContact CG1-CG2 4.41Å; I431-V435 HydrophobicContact CG2-CG2 4.46Å; I431-V435 WeakPolarHBondContact O-CG2 3.41Å; I431-V435 PolarHBondContact O-N 2.92Å; Y432-V435 PolarHBondContact O-N 2.98Å; V435-K437 VanDerWaalsContact C-N 3.26Å; V435-K437 PolarHBondContact O-N 3.32Å; V435-F438 WeakPolarHBondContact O-CB 3.44Å; V435-F438 PolarHBondContact O-N 3.33Å; V435-F439 HydrophobicContact CG1-CD2 3.69Å; V435-F439 HydrophobicContact CG1-CE2 3.78Å; V435-F439 WeakPolarHBondContact O-CD2 3.3Å; V435-F439 PolarHBondContact O-N 2.99Å; V435-Y493 HydrophobicContact CB-CD1 3.83Å; V435-Y493 HydrophobicContact CB-CE1 4.16Å; V435-Y493 HydrophobicContact CG1-CD1 3.66Å; V435-Y493 HydrophobicContact CG1-CE1 4.08Å; V435-Y493 HydrophobicContact CG2-CD1 4.34Å; V435-V494 HydrophobicContact CG1-CG2 3.97Å; V435-V494 HydrophobicContact CG2-CG2 3.75Å; V435-N497 HydrophobicContact CG1-CB 4.27Å
436D93.9Very high92.4Very high38 Ų3850.5 Ų50.520%0.20326%0.261CS..Hα-helixtrans-59.4-39.1176.9-69.3-14.4000110.8Y432 N440 V443 Y493Y432-D436 WeakPolarHBondContact O-CB 3.49Å; Y432-D436 PolarHBondContact O-N 3.23Å; D436-N440 WeakPolarHBondContact O-CA 3.35Å; D436-N440 PolarHBondContact O-N 2.68Å; D436-V443 WeakPolarHBondContact OD1-CG2 3.42Å; D436-Y493 WeakPolarHBondContact OD1-CE1 3.43Å; D436-Y493 PolarHBondContact OD1-OH 2.87Å; D436-Y493 PolarHBondContact OD2-OH 3.41Å
437K93.6Very high92.2Very high132 Ų13251.5 Ų51.557%0.57426%0.264SS*.Hα-helixtrans-65.6-36.1174.1179.1177.3171.7-174.90113V420 I421 N433 A434 V435V420-K437 HydrophobicContact CG1-CB 4.03Å; V420-K437 HydrophobicContact CG1-CD 3.82Å; V420-K437 HydrophobicContact CG1-CG 3.89Å; I421-K437 PolarHBondContact O-NZ 3.34Å; N433-K437 WeakPolarHBondContact O-CB 3.46Å; N433-K437 PolarHBondContact O-N 2.92Å; A434-K437 PolarHBondContact O-N 2.9Å; V435-K437 VanDerWaalsContact C-N 3.26Å; V435-K437 PolarHBondContact O-N 3.32Å
438F93.9Very high92Very high47 Ų4753.4 Ų53.421%0.20627%0.265CS..Hα-helixtrans-66.7-50.7176178.1-97.1000111.5F389 M410 V418 V420 A434 V435 N440F389-F438 HydrophobicContact CB-CE1 3.89Å; F389-F438 HydrophobicContact CB-CZ 3.58Å; F389-F438 HydrophobicContact CD1-CE2 4.43Å; F389-F438 AromaticContact CD1-CZ 3.99Å; F389-F438 HydrophobicContact CD1-CZ 3.99Å; F389-F438 AromaticContact CD2-CZ 3.76Å; F389-F438 HydrophobicContact CD2-CZ 3.76Å; F389-F438 HydrophobicContact CE2-CZ 4.42Å; F389-F438 HydrophobicContact CG-CE1 4.3Å; F389-F438 HydrophobicContact CG-CE2 4.36Å; F389-F438 AromaticContact CG-CZ 3.51Å; F389-F438 HydrophobicContact CG-CZ 3.51Å; M410-F438 HydrophobicContact CB-CD2 4.22Å; M410-F438 HydrophobicContact CB-CE2 3.79Å; M410-F438 HydrophobicContact CB-CZ 3.98Å; M410-F438 HydrophobicContact CE-CD1 3.89Å; M410-F438 HydrophobicContact CE-CE1 3.73Å; M410-F438 HydrophobicContact CE-CZ 4.25Å; M410-F438 HydrophobicContact CG-CD1 4.16Å; M410-F438 HydrophobicContact CG-CD2 3.73Å; M410-F438 HydrophobicContact CG-CE1 4.25Å; M410-F438 HydrophobicContact CG-CE2 3.81Å; M410-F438 HydrophobicContact CG-CG 3.9Å; M410-F438 HydrophobicContact CG-CZ 4.09Å; V418-F438 HydrophobicContact CB-CE2 4.05Å; V418-F438 HydrophobicContact CG1-CD2 4.11Å; V418-F438 HydrophobicContact CG1-CE2 3.89Å; V420-F438 HydrophobicContact CG2-CB 3.89Å; V420-F438 HydrophobicContact CG2-CD2 3.67Å; V420-F438 HydrophobicContact CG2-CG 4.24Å; A434-F438 PolarHBondContact O-N 2.97Å; V435-F438 WeakPolarHBondContact O-CB 3.44Å; V435-F438 PolarHBondContact O-N 3.33Å; F438-N440 VanDerWaalsContact C-N 3.34Å
439F91.3Very high91.5Very high15 Ų1554.3 Ų54.37%0.06627%0.271CS..Hα-helixtrans-76.7-21.8-178.2-75-80.2000113.3M410 V435 Q441 V494 N497 A498 Q501M410-F439 HydrophobicContact CE-CE2 4.35Å; M410-F439 HydrophobicContact CE-CZ 4.4Å; V435-F439 HydrophobicContact CG1-CD2 3.69Å; V435-F439 HydrophobicContact CG1-CE2 3.78Å; V435-F439 WeakPolarHBondContact O-CD2 3.3Å; V435-F439 PolarHBondContact O-N 2.99Å; F439-Q441 HydrophobicContact CB-CG 3.81Å; F439-Q441 PolarHBondContact O-N 3.25Å; F439-V494 HydrophobicContact CE2-CG1 4.33Å; F439-V494 HydrophobicContact CZ-CG1 4.27Å; F439-N497 HydrophobicContact CB-CB 4.49Å; F439-N497 HydrophobicContact CD1-CB 4.27Å; F439-N497 HydrophobicContact CD2-CB 3.4Å; F439-N497 HydrophobicContact CE1-CB 4.36Å; F439-N497 HydrophobicContact CE2-CB 3.51Å; F439-N497 HydrophobicContact CG-CB 3.81Å; F439-N497 HydrophobicContact CZ-CB 4.01Å; F439-A498 HydrophobicContact CE1-CB 4.19Å; F439-A498 HydrophobicContact CZ-CB 4.18Å; F439-Q501 HydrophobicContact CD1-CB 4.03Å; F439-Q501 HydrophobicContact CD1-CG 4.43Å; F439-Q501 HydrophobicContact CE1-CB 4.37Å
440N90.1Very high91.1Very high145 Ų14554.9 Ų54.978%0.77528%0.275SS*.THydrogen-bonded Turntrans51.552.1179.6-171.555000112.8D436 F438D436-N440 WeakPolarHBondContact O-CA 3.35Å; D436-N440 PolarHBondContact O-N 2.68Å; F438-N440 VanDerWaalsContact C-N 3.34Å
441Q85.8Confident90.1Very high23 Ų2359.3 Ų59.311%0.10730%0.299CS..  trans-137.4157.5-178.362.2-167.7-1.500111.2F439 V443 N497 V500 Q501 N504F439-Q441 HydrophobicContact CB-CG 3.81Å; F439-Q441 PolarHBondContact O-N 3.25Å; Q441-V443 HydrophobicContact CG-CG1 4.2Å; Q441-N497 VanDerWaalsContact NE2-CB 3.33Å; Q441-N497 PolarHBondContact NE2-O 2.9Å; Q441-N497 PolarHBondContact NE2-OD1 2.91Å; Q441-V500 HydrophobicContact CG-CG1 4.19Å; Q441-V500 VanDerWaalsContact OE1-CG1 3.25Å; Q441-Q501 VanDerWaalsContact OE1-N 3.1Å; Q441-N504 PolarHBondContact OE1-ND2 3.45Å
442T87.4Confident88.9Confident82 Ų8262.9 Ų62.950%0.50333%0.329SS..  trans-98.4106.9-176.5-48.90000110.4V470T442-V470 HydrophobicContact CG2-CB 3.98Å; T442-V470 HydrophobicContact CG2-CG1 4.39Å; T442-V470 HydrophobicContact CG2-CG2 4.02Å; T442-V470 PolarHBondContact O-N 2.78Å; T442-V470 VanDerWaalsContact O-N 3.14Å
443V91.9Very high87.5Confident22 Ų2265 Ų6513%0.13334%0.343CS..EExtended strand (participates in β ladder)trans-122.8156.3179.7-64.70000111.8D436 Q441 I467 E468 Y493 V500D436-V443 WeakPolarHBondContact OD1-CG2 3.42Å; Q441-V443 HydrophobicContact CG-CG1 4.2Å; V443-I467 HydrophobicContact CB-CD1 4.3Å; V443-I467 HydrophobicContact CG1-CD1 4.11Å; V443-E468 CarbonylContact C-O 3.2Å; V443-E468 VanDerWaalsContact CA-O 3.27Å; V443-E468 WeakPolarHBondContact CA-O 3.5Å; V443-Y493 VanDerWaalsContact CG2-OH 3.32Å; V443-Y493 WeakPolarHBondContact CG2-OH 3.49Å; V443-V500 HydrophobicContact CG1-CB 4.19Å; V443-V500 HydrophobicContact CG1-CG1 3.78Å; V443-V500 HydrophobicContact CG1-CG2 3.82Å
444R92Very high85.4Confident132 Ų13265.7 Ų65.750%0.49835%0.349SS..EExtended strand (participates in β ladder)trans-123.2120.5174.6176.3166.366.8-1654.6110.2L446 I467 E468 V470R444-L446 HydrophobicContact CG-CD2 4.26Å; R444-L446 PolarHBondContact O-N 3.19Å; R444-I467 CarbonylContact O-C 3.6Å; R444-I467 WeakPolarHBondContact O-CA 3.46Å; R444-E468 HydrophobicContact CB-CB 4.36Å; R444-E468 IonicContact CZ-OE1 2.82Å; R444-E468 IonicContact CZ-OE2 3.66Å; R444-E468 PolarHBondContact N-O 3.2Å; R444-E468 IonicContact NE-OE2 3.89Å; R444-E468 PolarHBondContact NE-OE2 3.09Å; R444-E468 IonicContact NH2-OE1 2.82Å; R444-E468 PolarHBondContact NH2-OE1 2.94Å; R444-E468 IonicContact NH2-OE2 3.7Å; R444-E468 PolarHBondContact NH2-OE2 3.06Å; R444-E468 PolarHBondContact O-N 2.72Å; R444-V470 HydrophobicContact CB-CG2 4Å
445L91.8Very high83.5Confident68 Ų6873.1 Ų73.136%0.35639%0.389SS..EExtended strand (participates in β ladder)trans-69.7122171.9-175.571.7000110.2Y432 S447 V465 I467 Y493Y432-L445 HydrophobicContact CD2-CD2 4.29Å; Y432-L445 HydrophobicContact CE2-CD1 4.11Å; Y432-L445 HydrophobicContact CE2-CD2 3.82Å; L445-S447 WeakPolarHBondContact CD1-O 3.42Å; L445-V465 HydrophobicContact CD1-CB 4.09Å; L445-V465 HydrophobicContact CD1-CG1 4.33Å; L445-I467 HydrophobicContact CD1-CG2 3.93Å; L445-Y493 HydrophobicContact CD1-CD2 4.37Å; L445-Y493 HydrophobicContact CD1-CE2 4.16Å
446L84Confident81.8Confident82 Ų8275.7 Ų75.743%0.42942%0.415SS..EExtended strand (participates in β ladder)trans-98.6-40.1177.9-62.5-176.4000112.5R444 S466 E468 I475R444-L446 HydrophobicContact CG-CD2 4.26Å; R444-L446 PolarHBondContact O-N 3.19Å; L446-S466 PolarHBondContact N-O 2.97Å; L446-E468 HydrophobicContact CD1-CB 4.01Å; L446-E468 HydrophobicContact CD2-CB 4.4Å; L446-E468 HydrophobicContact CG-CB 4.11Å; L446-I475 HydrophobicContact CD1-CB 4.4Å; L446-I475 HydrophobicContact CD1-CD1 3.49Å; L446-I475 VanDerWaalsContact CD1-CD1 3.49Å; L446-I475 HydrophobicContact CD1-CG1 3.63Å; L446-I475 HydrophobicContact CD1-CG2 3.9Å
447S85.5Confident80.7Confident47 Ų4782.8 Ų82.833%0.32945%0.451SS..EExtended strand (participates in β ladder)trans-143.8148.3-179.589.70000111.6L445 V465 S466L445-S447 WeakPolarHBondContact CD1-O 3.42Å; S447-V465 WeakPolarHBondContact O-CA 3.49Å; S447-S466 PolarHBondContact N-O 3.49Å; S447-S466 PolarHBondContact O-N 3.31Å; S447-S466 VanDerWaalsContact OG-CB 3.25Å; S447-S466 WeakPolarHBondContact OG-CB 3.48Å; S447-S466 PolarHBondContact OG-N 2.87Å; S447-S466 PolarHBondContact OG-OG 3.36Å
448Y88.7Confident79.7Confident79 Ų7982 Ų8231%0.3145%0.453SS..EExtended strand (participates in β ladder)trans-141.1118.6173176.4-80.3000107.2V428 Y432 M450 V463 S464 V465V428-Y448 HydrophobicContact CG1-CE2 4.48Å; Y432-Y448 WeakPolarHBondContact OH-CD2 3.39Å; Y448-M450 HydrophobicContact CE1-CB 4.11Å; Y448-V463 HydrophobicContact CD2-CG1 3.97Å; Y448-V463 HydrophobicContact CE1-CG1 4.47Å; Y448-V463 HydrophobicContact CE2-CG1 3.41Å; Y448-V463 VanDerWaalsContact CE2-CG1 3.41Å; Y448-S464 WeakPolarHBondContact CA-O 3.5Å; Y448-V465 HydrophobicContact CD2-CG1 4Å
449T82.5Confident78.5Confident71 Ų7180.9 Ų80.944%0.43645%0.451SS..EExtended strand (participates in β ladder)trans-127.5144174.3610000110.1V463 S464T449-V463 CarbonylContact O-C 3.51Å; T449-V463 WeakPolarHBondContact O-CA 3.38Å; T449-S464 PolarHBondContact N-O 3.36Å; T449-S464 PolarHBondContact O-N 2.9Å
450M85.8Confident77.6Confident97 Ų9783.2 Ų83.248%0.47846%0.462SS..EExtended strand (participates in β ladder)trans-133.6126.8-179178.9-178.770.300109Y448 R462 V463 V485Y448-M450 HydrophobicContact CE1-CB 4.11Å; M450-R462 WeakPolarHBondContact CA-O 3.25Å; M450-V463 HydrophobicContact CB-CG2 4.23Å; M450-V463 HydrophobicContact CG-CG2 4Å; M450-V485 HydrophobicContact SD-CB 3.64Å; M450-V485 HydrophobicContact SD-CG1 3.5Å; M450-V485 VanDerWaalsContact SD-CG1 3.5Å
451D75.6Confident77Confident93 Ų9376.6 Ų76.650%0.49743%0.428SS..EExtended strand (participates in β ladder)trans-125.8140179.9-60.6-68.7000109.5R462D451-R462 PolarHBondContact N-O 3.42Å; D451-R462 PolarHBondContact O-N 3.33Å
452A71.8Confident76.8Confident77 Ų7780.7 Ų80.764%0.63644%0.442SS*.EExtended strand (participates in β ladder)trans-70.9132.4164.100000109.2
453V64.8Low76.7Confident58 Ų5876.8 Ų76.835%0.35242%0.418SS..SBendtrans-84.1-34.2177.6-178.90000110.7Q460 R462V453-Q460 HydrophobicContact CB-CB 4.04Å; V453-Q460 WeakPolarHBondContact CB-O 3.38Å; V453-Q460 HydrophobicContact CG2-CB 4.19Å; V453-Q460 WeakPolarHBondContact CG2-O 2.96Å; V453-Q460 PolarHBondContact N-O 3.21Å; V453-R462 HydrophobicContact CG2-CB 3.71Å
454T51Low76.2Confident71 Ų7177.4 Ų77.444%0.43642%0.423SS..SBendtrans-132.5168.2177.859.20000110.8S459T454-S459 PolarHBondContact N-OG 3.08Å; T454-S459 WeakPolarHBondContact O-CB 3.39Å; T454-S459 PolarHBondContact O-OG 3.17Å; T454-S459 WeakPolarHBondContact OG1-CA 3.37Å
455D57.2Low76Confident157 Ų15771.2 Ų71.284%0.8440%0.4SS*.SBendtrans-83.9163.3170.4-61.8-48.9000110.6
456G59.7Low75.6Confident54 Ų5469 Ų6956%0.55739%0.39SS*.SBendtrans102.5170.5173.800000114.7D458 S459G456-D458 PolarHBondContact O-N 2.85Å; G456-S459 VanDerWaalsContact O-CB 3.25Å; G456-S459 WeakPolarHBondContact O-CB 3.42Å; G456-S459 PolarHBondContact O-N 2.79Å
457I70.9Confident75.8Confident186 Ų18665 Ų6595%0.95437%0.37SS*.THydrogen-bonded Turntrans-72.3-16.4-179.360.7170.4000112.9
458D71.4Confident75.9Confident116 Ų11664.2 Ų64.262%0.6236%0.361SS*.THydrogen-bonded Turntrans-100.618.1176.360.4-29.6000111.9G456 F483G456-D458 PolarHBondContact O-N 2.85Å; D458-F483 WeakPolarHBondContact O-CD1 3.39Å; D458-F483 WeakPolarHBondContact O-CE1 3.32Å
459S68.6Low75.8Confident23 Ų2360.5 Ų60.516%0.16135%0.346CS..PPolyproline II helixtrans-61.3138178.3179.40000112.4T454 G456T454-S459 PolarHBondContact N-OG 3.08Å; T454-S459 WeakPolarHBondContact O-CB 3.39Å; T454-S459 PolarHBondContact O-OG 3.17Å; T454-S459 WeakPolarHBondContact OG1-CA 3.37Å; G456-S459 VanDerWaalsContact O-CB 3.25Å; G456-S459 WeakPolarHBondContact O-CB 3.42Å; G456-S459 PolarHBondContact O-N 2.79Å
460Q72.5Confident76.1Confident64 Ų6460.6 Ų60.630%0.29935%0.346SS..PPolyproline II helixtrans-77141167.1-69.1180-5.300110.3V453 I481 D482 F483V453-Q460 HydrophobicContact CB-CB 4.04Å; V453-Q460 WeakPolarHBondContact CB-O 3.38Å; V453-Q460 HydrophobicContact CG2-CB 4.19Å; V453-Q460 WeakPolarHBondContact CG2-O 2.96Å; V453-Q460 PolarHBondContact N-O 3.21Å; Q460-I481 HydrophobicContact CB-CG2 4.37Å; Q460-D482 WeakPolarHBondContact CA-O 3.48Å; Q460-F483 HydrophobicContact CG-CD1 3.67Å; Q460-F483 HydrophobicContact CG-CD2 4.36Å; Q460-F483 HydrophobicContact CG-CE1 3.55Å; Q460-F483 HydrophobicContact CG-CE2 4.25Å; Q460-F483 HydrophobicContact CG-CG 4.1Å; Q460-F483 HydrophobicContact CG-CZ 3.87Å
461A77.4Confident76Confident6 Ų661.5 Ų61.55%0.0535%0.353CS..EExtended strand (participates in β ladder)trans-97.4132.7171.800000110.1I481 D482 V485 A488A461-I481 WeakPolarHBondContact O-CA 3.15Å; A461-D482 PolarHBondContact N-O 3.01Å; A461-D482 PolarHBondContact O-N 3.27Å; A461-D482 VanDerWaalsContact O-N 3.16Å; A461-V485 HydrophobicContact CB-CB 4.17Å; A461-V485 HydrophobicContact CB-CG1 3.49Å; A461-V485 VanDerWaalsContact CB-CG1 3.49Å; A461-A488 HydrophobicContact CB-CB 4.37Å; A461-A488 WeakPolarHBondContact O-CB 3.34Å
462R81.2Confident76.2Confident109 Ų10958.1 Ų58.141%0.41134%0.336SS..EExtended strand (participates in β ladder)trans-102.9122.4164.2-179.6179.4-59.9176.74.1108.2M450 D451 V453 G480 I481M450-R462 WeakPolarHBondContact CA-O 3.25Å; D451-R462 PolarHBondContact N-O 3.42Å; D451-R462 PolarHBondContact O-N 3.33Å; V453-R462 HydrophobicContact CG2-CB 3.71Å; R462-G480 WeakPolarHBondContact CA-O 3.21Å; R462-I481 HydrophobicContact CB-CG1 4.2Å; R462-I481 HydrophobicContact CG-CG1 4.05Å
463V86.1Confident76.6Confident0 Ų056.1 Ų56.10%032%0.323CS..EExtended strand (participates in β ladder)trans-109.6132.5171.8178.10000108.7Y448 T449 M450 V465 S479 G480 A488 A492Y448-V463 HydrophobicContact CD2-CG1 3.97Å; Y448-V463 HydrophobicContact CE1-CG1 4.47Å; Y448-V463 HydrophobicContact CE2-CG1 3.41Å; Y448-V463 VanDerWaalsContact CE2-CG1 3.41Å; T449-V463 CarbonylContact O-C 3.51Å; T449-V463 WeakPolarHBondContact O-CA 3.38Å; M450-V463 HydrophobicContact CB-CG2 4.23Å; M450-V463 HydrophobicContact CG-CG2 4Å; V463-V465 HydrophobicContact CG1-CG1 4.22Å; V463-S479 CarbonylContact O-C 3.49Å; V463-S479 WeakPolarHBondContact O-CA 3.24Å; V463-S479 WeakPolarHBondContact O-CB 3.34Å; V463-G480 PolarHBondContact N-O 3.02Å; V463-G480 PolarHBondContact O-N 2.82Å; V463-A488 HydrophobicContact CB-CB 4.22Å; V463-A488 HydrophobicContact CG2-CB 3.77Å; V463-A492 HydrophobicContact CB-CB 4.49Å; V463-A492 HydrophobicContact CG1-CB 4.3Å
464S82.5Confident77.1Confident35 Ų3553.3 Ų53.325%0.24531%0.306CS..EExtended strand (participates in β ladder)trans-118.3137.1172.7-51.10000109.6Y448 T449 A478Y448-S464 WeakPolarHBondContact CA-O 3.5Å; T449-S464 PolarHBondContact N-O 3.36Å; T449-S464 PolarHBondContact O-N 2.9Å; S464-A478 WeakPolarHBondContact CA-O 3.36Å
465V87.1Confident78.3Confident2 Ų252.7 Ų52.71%0.01230%0.299CS..EExtended strand (participates in β ladder)trans-127.9146.2179.3-59.60000110.8Y432 L445 S447 Y448 V463 N477 A478 A492 A496Y432-V465 WeakPolarHBondContact OH-CG1 3.38Å; L445-V465 HydrophobicContact CD1-CB 4.09Å; L445-V465 HydrophobicContact CD1-CG1 4.33Å; S447-V465 WeakPolarHBondContact O-CA 3.49Å; Y448-V465 HydrophobicContact CD2-CG1 4Å; V463-V465 HydrophobicContact CG1-CG1 4.22Å; V465-N477 VanDerWaalsContact O-CA 3.3Å; V465-N477 WeakPolarHBondContact O-CA 3.41Å; V465-A478 HydrophobicContact CG2-CB 4.41Å; V465-A478 PolarHBondContact N-O 2.76Å; V465-A478 PolarHBondContact O-N 3.35Å; V465-A492 HydrophobicContact CG1-CB 4.04Å; V465-A492 HydrophobicContact CG2-CB 3.95Å; V465-A496 HydrophobicContact CG2-CB 3.92Å
466S82.5Confident79.3Confident21 Ų2145.4 Ų45.415%0.14726%0.26CS..EExtended strand (participates in β ladder)trans-115.7121.1165.3-59.10000108.4L446 S447 F476 N477L446-S466 PolarHBondContact N-O 2.97Å; S447-S466 PolarHBondContact N-O 3.49Å; S447-S466 PolarHBondContact O-N 3.31Å; S447-S466 VanDerWaalsContact OG-CB 3.25Å; S447-S466 WeakPolarHBondContact OG-CB 3.48Å; S447-S466 PolarHBondContact OG-N 2.87Å; S447-S466 PolarHBondContact OG-OG 3.36Å; S466-F476 CarbonylContact C-O 3.53Å; S466-F476 WeakPolarHBondContact CA-O 3.21Å; S466-N477 WeakPolarHBondContact CA-OD1 3.24Å; S466-N477 WeakPolarHBondContact CB-OD1 3.44Å; S466-N477 PolarHBondContact OG-OD1 2.7Å
467I88.2Confident80.2Confident0 Ų044.8 Ų44.80%024%0.244CC..EExtended strand (participates in β ladder)trans-120.6145.2175.175.8176.3000110.5V443 R444 L445 I475 F476 Y493 A496 V500V443-I467 HydrophobicContact CB-CD1 4.3Å; V443-I467 HydrophobicContact CG1-CD1 4.11Å; R444-I467 CarbonylContact O-C 3.6Å; R444-I467 WeakPolarHBondContact O-CA 3.46Å; L445-I467 HydrophobicContact CD1-CG2 3.93Å; I467-I475 CarbonylContact O-C 3.39Å; I467-I475 WeakPolarHBondContact O-CA 3.49Å; I467-F476 HydrophobicContact CG1-CB 4.19Å; I467-F476 PolarHBondContact N-O 2.99Å; I467-F476 PolarHBondContact O-N 2.8Å; I467-Y493 HydrophobicContact CG2-CD2 3.85Å; I467-Y493 HydrophobicContact CG2-CE2 3.53Å; I467-A496 VanDerWaalsContact CD1-C 3.44Å; I467-A496 HydrophobicContact CD1-CB 3.46Å; I467-A496 VanDerWaalsContact CD1-CB 3.46Å; I467-A496 HydrophobicContact CG1-CB 3.78Å; I467-A496 HydrophobicContact CG2-CB 4.17Å; I467-V500 HydrophobicContact CD1-CG2 3.69Å; I467-V500 HydrophobicContact CG1-CG2 4.17Å
468E87.7Confident80.5Confident30 Ų3036.6 Ų36.614%0.1420%0.204CC..EExtended strand (participates in β ladder)trans-105.8129.2174.7-178-173.8-172.800109.9V443 R444 L446 V470 T474 I475V443-E468 CarbonylContact C-O 3.2Å; V443-E468 VanDerWaalsContact CA-O 3.27Å; V443-E468 WeakPolarHBondContact CA-O 3.5Å; R444-E468 HydrophobicContact CB-CB 4.36Å; R444-E468 IonicContact CZ-OE1 2.82Å; R444-E468 IonicContact CZ-OE2 3.66Å; R444-E468 PolarHBondContact N-O 3.2Å; R444-E468 IonicContact NE-OE2 3.89Å; R444-E468 PolarHBondContact NE-OE2 3.09Å; R444-E468 IonicContact NH2-OE1 2.82Å; R444-E468 PolarHBondContact NH2-OE1 2.94Å; R444-E468 IonicContact NH2-OE2 3.7Å; R444-E468 PolarHBondContact NH2-OE2 3.06Å; R444-E468 PolarHBondContact O-N 2.72Å; L446-E468 HydrophobicContact CD1-CB 4.01Å; L446-E468 HydrophobicContact CD2-CB 4.4Å; L446-E468 HydrophobicContact CG-CB 4.11Å; E468-V470 PolarHBondContact O-N 2.76Å; E468-T474 CarbonylContact C-O 3.45Å; E468-T474 VanDerWaalsContact CA-O 3.28Å; E468-T474 WeakPolarHBondContact CA-O 3.3Å; E468-I475 HydrophobicContact CB-CG1 4.35Å; E468-I475 HydrophobicContact CG-CG1 4.39Å
469N87.6Confident80.9Confident0 Ų034 Ų340%020%0.195CC..EExtended strand (participates in β ladder)trans-71.2114.3164.7-177.9-9000108.5D471 T472 G473 T474 F476 V500 E503 N504N469-D471 PolarHBondContact O-N 2.91Å; N469-D471 PolarHBondContact OD1-N 3.07Å; N469-T472 WeakPolarHBondContact CB-OG1 3.41Å; N469-T472 PolarHBondContact ND2-OG1 2.74Å; N469-T472 PolarHBondContact O-N 3.41Å; N469-G473 WeakPolarHBondContact O-CA 3.22Å; N469-G473 PolarHBondContact O-N 2.78Å; N469-T474 PolarHBondContact N-O 2.93Å; N469-F476 HydrophobicContact CB-CE2 4.25Å; N469-V500 HydrophobicContact CB-CG1 3.89Å; N469-V500 HydrophobicContact CB-CG2 4.28Å; N469-E503 WeakPolarHBondContact CB-OE2 3.3Å; N469-E503 PolarHBondContact ND2-OE2 3.17Å; N469-N504 PolarHBondContact ND2-OD1 3.3Å
470V88.5Confident81.4Confident73 Ų7333.1 Ų33.144%0.44219%0.189SC..THydrogen-bonded Turntrans-66.4-26.3-174.9178.80000111.8T442 R444 E468T442-V470 HydrophobicContact CG2-CB 3.98Å; T442-V470 HydrophobicContact CG2-CG1 4.39Å; T442-V470 HydrophobicContact CG2-CG2 4.02Å; T442-V470 PolarHBondContact O-N 2.78Å; T442-V470 VanDerWaalsContact O-N 3.14Å; R444-V470 HydrophobicContact CB-CG2 4Å; E468-V470 PolarHBondContact O-N 2.76Å
471D84.1Confident81.7Confident116 Ų11633.7 Ų33.762%0.6219%0.194SC*.THydrogen-bonded Turntrans-76.2-28.6-178.3-65.4-33.5000112.6N469N469-D471 PolarHBondContact O-N 2.91Å; N469-D471 PolarHBondContact OD1-N 3.07Å
472T80.3Confident82.1Confident23 Ų2335.7 Ų35.714%0.14120%0.203CC..THydrogen-bonded Turntrans-116.3-17.3-175.663.20000113.8N469 T474 E503 A511N469-T472 WeakPolarHBondContact CB-OG1 3.41Å; N469-T472 PolarHBondContact ND2-OG1 2.74Å; N469-T472 PolarHBondContact O-N 3.41Å; T472-T474 PolarHBondContact O-N 3Å; T472-T474 WeakPolarHBondContact OG1-CB 3.26Å; T472-T474 PolarHBondContact OG1-N 3.17Å; T472-T474 PolarHBondContact OG1-OG1 3.23Å; T472-E503 WeakPolarHBondContact CB-OE1 3.43Å; T472-E503 HydrophobicContact CG2-CG 4.29Å; T472-E503 PolarHBondContact OG1-OE1 3.19Å; T472-E503 PolarHBondContact OG1-OE2 3.24Å; T472-A511 WeakPolarHBondContact O-CB 3.25Å
473G79.5Confident82.3Confident34 Ų3437 Ų3735%0.35121%0.213SC..  trans73.37.6-170.400000114.1N469N469-G473 WeakPolarHBondContact O-CA 3.22Å; N469-G473 PolarHBondContact O-N 2.78Å
474T74.8Confident82.5Confident0 Ų040.3 Ų40.30%023%0.23CC..  trans-76.4132-177.2-61.20000111.8A372 R375 E468 N469 T472 F476 E503A372-T474 HydrophobicContact CB-CG2 3.61Å; R375-T474 WeakPolarHBondContact CD-OG1 3.34Å; E468-T474 CarbonylContact C-O 3.45Å; E468-T474 VanDerWaalsContact CA-O 3.28Å; E468-T474 WeakPolarHBondContact CA-O 3.3Å; N469-T474 PolarHBondContact N-O 2.93Å; T472-T474 PolarHBondContact O-N 3Å; T472-T474 WeakPolarHBondContact OG1-CB 3.26Å; T472-T474 PolarHBondContact OG1-N 3.17Å; T472-T474 PolarHBondContact OG1-OG1 3.23Å; T474-F476 HydrophobicContact CG2-CD2 4.17Å; T474-F476 HydrophobicContact CG2-CE1 3.98Å; T474-F476 HydrophobicContact CG2-CE2 3.53Å; T474-F476 HydrophobicContact CG2-CZ 3.42Å; T474-F476 VanDerWaalsContact CG2-CZ 3.42Å; T474-E503 WeakPolarHBondContact CB-OE1 3.41Å; T474-E503 PolarHBondContact OG1-OE1 2.96Å
475I76.9Confident82.9Confident57 Ų5741.6 Ų41.629%0.29224%0.236SC..EExtended strand (participates in β ladder)trans-101.6114.5-179.6-57.5172.7000111.6A372 L446 I467 E468A372-I475 WeakPolarHBondContact CB-O 3.34Å; L446-I475 HydrophobicContact CD1-CB 4.4Å; L446-I475 HydrophobicContact CD1-CD1 3.49Å; L446-I475 VanDerWaalsContact CD1-CD1 3.49Å; L446-I475 HydrophobicContact CD1-CG1 3.63Å; L446-I475 HydrophobicContact CD1-CG2 3.9Å; I467-I475 CarbonylContact O-C 3.39Å; I467-I475 WeakPolarHBondContact O-CA 3.49Å; E468-I475 HydrophobicContact CB-CG1 4.35Å; E468-I475 HydrophobicContact CG-CG1 4.39Å
476F78.3Confident83.3Confident4 Ų443.4 Ų43.42%0.01825%0.246CC..EExtended strand (participates in β ladder)trans-100.4132.4176-61.4-80.8000111.6A372 S466 I467 N469 T474 F499 V500 E503 I508A372-F476 HydrophobicContact CB-CD1 3.39Å; A372-F476 HydrophobicContact CB-CE1 3.56Å; A372-F476 HydrophobicContact CB-CG 4.03Å; A372-F476 HydrophobicContact CB-CZ 4.31Å; S466-F476 CarbonylContact C-O 3.53Å; S466-F476 WeakPolarHBondContact CA-O 3.21Å; I467-F476 HydrophobicContact CG1-CB 4.19Å; I467-F476 PolarHBondContact N-O 2.99Å; I467-F476 PolarHBondContact O-N 2.8Å; N469-F476 HydrophobicContact CB-CE2 4.25Å; T474-F476 HydrophobicContact CG2-CD2 4.17Å; T474-F476 HydrophobicContact CG2-CE1 3.98Å; T474-F476 HydrophobicContact CG2-CE2 3.53Å; T474-F476 HydrophobicContact CG2-CZ 3.42Å; T474-F476 VanDerWaalsContact CG2-CZ 3.42Å; F476-F499 HydrophobicContact CB-CB 4.29Å; F476-F499 HydrophobicContact CB-CD2 4.36Å; F476-F499 HydrophobicContact CD1-CB 3.31Å; F476-F499 HydrophobicContact CD1-CD2 4.31Å; F476-F499 HydrophobicContact CD1-CG 4.09Å; F476-F499 HydrophobicContact CE1-CB 3.67Å; F476-F499 HydrophobicContact CG-CB 3.8Å; F476-F499 HydrophobicContact CZ-CB 4.41Å; F476-V500 HydrophobicContact CD2-CG2 3.43Å; F476-V500 VanDerWaalsContact CD2-CG2 3.43Å; F476-V500 HydrophobicContact CE2-CB 4.39Å; F476-V500 HydrophobicContact CE2-CG2 3.68Å; F476-V500 HydrophobicContact CG-CG2 4.32Å; F476-E503 WeakPolarHBondContact CE2-OE2 3.44Å; F476-E503 HydrophobicContact CZ-CB 3.99Å; F476-E503 HydrophobicContact CZ-CG 4.42Å; F476-E503 WeakPolarHBondContact CZ-OE2 3.36Å; F476-I508 HydrophobicContact CE1-CD1 4.29Å; F476-I508 HydrophobicContact CZ-CG2 4.49Å
477N77.8Confident83.8Confident42 Ų4244.9 Ų44.923%0.22525%0.249CC..EExtended strand (participates in β ladder)trans-108.1136.4172.6-64.7-24000110T370 V465 S466T370-N477 HydrophobicContact CG2-CB 3.94Å; T370-N477 WeakPolarHBondContact CG2-ND2 3.43Å; V465-N477 VanDerWaalsContact O-CA 3.3Å; V465-N477 WeakPolarHBondContact O-CA 3.41Å; S466-N477 WeakPolarHBondContact CA-OD1 3.24Å; S466-N477 WeakPolarHBondContact CB-OD1 3.44Å; S466-N477 PolarHBondContact OG-OD1 2.7Å
478A78.2Confident83.9Confident14 Ų1444.9 Ų44.912%0.11625%0.249CC..EExtended strand (participates in β ladder)trans-145.1160.4173.400000111S464 V465 A492 N495 A496 F499S464-A478 WeakPolarHBondContact CA-O 3.36Å; V465-A478 HydrophobicContact CG2-CB 4.41Å; V465-A478 PolarHBondContact N-O 2.76Å; V465-A478 PolarHBondContact O-N 3.35Å; A478-A492 VanDerWaalsContact CB-O 3.28Å; A478-A492 WeakPolarHBondContact CB-O 3.11Å; A478-N495 HydrophobicContact CB-CB 3.78Å; A478-A496 HydrophobicContact CB-CB 3.81Å; A478-F499 HydrophobicContact CB-CE2 4.3Å
479S78.3Confident84.2Confident62 Ų6243.6 Ų43.643%0.43424%0.244SC..EExtended strand (participates in β ladder)trans-130.3153.9175.961.70000111.4V463 N495V463-S479 CarbonylContact O-C 3.49Å; V463-S479 WeakPolarHBondContact O-CA 3.24Å; V463-S479 WeakPolarHBondContact O-CB 3.34Å; S479-N495 PolarHBondContact O-ND2 2.89Å
480G79.7Confident84.5Confident3 Ų343.6 Ų43.63%0.03124%0.244CC..EExtended strand (participates in β ladder)trans-132.5148.4171.100000110R462 V463 A488R462-G480 WeakPolarHBondContact CA-O 3.21Å; V463-G480 PolarHBondContact N-O 3.02Å; V463-G480 PolarHBondContact O-N 2.82Å; G480-A488 WeakPolarHBondContact CA-O 3.48Å
481I79.2Confident84.7Confident77 Ų7741.8 Ų41.840%0.39523%0.232SC..EExtended strand (participates in β ladder)trans-131.7127.8178.9-58.7175.7000107.3Q460 A461 R462Q460-I481 HydrophobicContact CB-CG2 4.37Å; A461-I481 WeakPolarHBondContact O-CA 3.15Å; R462-I481 HydrophobicContact CB-CG1 4.2Å; R462-I481 HydrophobicContact CG-CG1 4.05Å
482D86.5Confident84.9Confident47 Ų4736.2 Ų36.225%0.25120%0.202SC..EExtended strand (participates in β ladder)trans-154.7168.7174.9-161.9-82.6000109.2Q460 A461 D484 K487 A488 I491Q460-D482 WeakPolarHBondContact CA-O 3.48Å; A461-D482 PolarHBondContact N-O 3.01Å; A461-D482 PolarHBondContact O-N 3.27Å; A461-D482 VanDerWaalsContact O-N 3.16Å; D482-D484 VanDerWaalsContact C-N 3.28Å; D482-D484 PolarHBondContact OD1-N 3.16Å; D482-K487 HydrophobicContact CB-CB 3.91Å; D482-A488 HydrophobicContact CB-CB 3.97Å; D482-I491 HydrophobicContact CB-CD1 4.26Å
483F84.3Confident85.6Confident138 Ų13835.4 Ų35.461%0.60520%0.196SC*.SBendtrans-73.8-25.3168.9-71.7-83.4000111.7D458 Q460D458-F483 WeakPolarHBondContact O-CD1 3.39Å; D458-F483 WeakPolarHBondContact O-CE1 3.32Å; Q460-F483 HydrophobicContact CG-CD1 3.67Å; Q460-F483 HydrophobicContact CG-CD2 4.36Å; Q460-F483 HydrophobicContact CG-CE1 3.55Å; Q460-F483 HydrophobicContact CG-CE2 4.25Å; Q460-F483 HydrophobicContact CG-CG 4.1Å; Q460-F483 HydrophobicContact CG-CZ 3.87Å
484D90.4Very high86.2Confident68 Ų6833.8 Ų33.836%0.36418%0.18SC..SBendtrans-97.3122.4174.1-174.2-55.8000110.7D482 L486 K487 A488D482-D484 VanDerWaalsContact C-N 3.28Å; D482-D484 PolarHBondContact OD1-N 3.16Å; D484-L486 PolarHBondContact O-N 3.4Å; D484-L486 WeakPolarHBondContact OD1-CA 3.47Å; D484-L486 VanDerWaalsContact OD1-CB 3.27Å; D484-L486 WeakPolarHBondContact OD1-CB 3.33Å; D484-L486 PolarHBondContact OD1-N 3.48Å; D484-K487 HydrophobicContact CB-CB 4.04Å; D484-K487 HydrophobicContact CB-CD 4.12Å; D484-K487 HydrophobicContact CB-CG 3.86Å; D484-K487 PolarHBondContact O-N 2.75Å; D484-K487 PolarHBondContact OD1-N 3.35Å; D484-A488 PolarHBondContact O-N 2.93Å
485V91.2Very high86.8Confident63 Ų6336.7 Ų36.738%0.38220%0.195SC..Hα-helixtrans-57-33.5-179.6-64.50000113.4M450 A461 G489M450-V485 HydrophobicContact SD-CB 3.64Å; M450-V485 HydrophobicContact SD-CG1 3.5Å; M450-V485 VanDerWaalsContact SD-CG1 3.5Å; A461-V485 HydrophobicContact CB-CB 4.17Å; A461-V485 HydrophobicContact CB-CG1 3.49Å; A461-V485 VanDerWaalsContact CB-CG1 3.49Å; V485-G489 PolarHBondContact O-N 3.21Å
486L94.7Very high87.3Confident39 Ų3934 Ų3420%0.20418%0.182CC..Hα-helixtrans-78.8-36.8-179.1-58.5174.5000110.9L394 L396 V428 I431 D484 G489 A490L394-L486 HydrophobicContact CD2-CB 3.94Å; L396-L486 HydrophobicContact CD1-CB 4.39Å; L396-L486 HydrophobicContact CD1-CD1 3.34Å; L396-L486 HydrophobicContact CD1-CG 4.43Å; V428-L486 HydrophobicContact CG2-CD2 4.19Å; I431-L486 HydrophobicContact CD1-CB 3.94Å; I431-L486 HydrophobicContact CD1-CD2 4.4Å; D484-L486 PolarHBondContact O-N 3.4Å; D484-L486 WeakPolarHBondContact OD1-CA 3.47Å; D484-L486 VanDerWaalsContact OD1-CB 3.27Å; D484-L486 WeakPolarHBondContact OD1-CB 3.33Å; D484-L486 PolarHBondContact OD1-N 3.48Å; L486-G489 PolarHBondContact O-N 2.87Å; L486-A490 WeakPolarHBondContact O-CB 3.43Å; L486-A490 PolarHBondContact O-N 2.6Å
487K94.3Very high87.9Confident52 Ų5233.8 Ų33.823%0.22618%0.181CC..Hα-helixtrans-65.4-44.6170.9-64.9-167.7-174.2-159.10111.4F391 D393 L394 D482 D484 G489 A490 I491F391-K487 HydrophobicContact CE1-CB 4.26Å; F391-K487 HydrophobicContact CE1-CD 4.5Å; F391-K487 HydrophobicContact CE1-CG 4.42Å; F391-K487 HydrophobicContact CZ-CB 4.25Å; F391-K487 HydrophobicContact CZ-CG 4.15Å; D393-K487 WeakPolarHBondContact OD1-CE 3.19Å; D393-K487 IonicContact OD1-NZ 3.89Å; D393-K487 PolarHBondContact OD1-NZ 2.62Å; L394-K487 HydrophobicContact CB-CG 4.25Å; L394-K487 HydrophobicContact CD2-CG 4.36Å; D482-K487 HydrophobicContact CB-CB 3.91Å; D484-K487 HydrophobicContact CB-CB 4.04Å; D484-K487 HydrophobicContact CB-CD 4.12Å; D484-K487 HydrophobicContact CB-CG 3.86Å; D484-K487 PolarHBondContact O-N 2.75Å; D484-K487 PolarHBondContact OD1-N 3.35Å; K487-G489 VanDerWaalsContact C-N 3.26Å; K487-G489 PolarHBondContact O-N 3.46Å; K487-A490 WeakPolarHBondContact O-CB 3.29Å; K487-A490 PolarHBondContact O-N 3.07Å; K487-A490 VanDerWaalsContact O-N 3.11Å; K487-I491 VanDerWaalsContact O-CG1 3.28Å; K487-I491 WeakPolarHBondContact O-CG1 3.32Å; K487-I491 PolarHBondContact O-N 3.45Å
488A89.8Confident88.4Confident0 Ų032.1 Ų32.10%017%0.173CC..Hα-helixtrans-56.2-43.3173.900000111.3A461 V463 G480 D482 D484 I491 A492A461-A488 HydrophobicContact CB-CB 4.37Å; A461-A488 WeakPolarHBondContact O-CB 3.34Å; V463-A488 HydrophobicContact CB-CB 4.22Å; V463-A488 HydrophobicContact CG2-CB 3.77Å; G480-A488 WeakPolarHBondContact CA-O 3.48Å; D482-A488 HydrophobicContact CB-CB 3.97Å; D484-A488 PolarHBondContact O-N 2.93Å; A488-I491 PolarHBondContact O-N 2.86Å; A488-A492 WeakPolarHBondContact O-CB 3.33Å; A488-A492 PolarHBondContact O-N 2.98Å
489G93.6Very high88.6Confident3 Ų333.8 Ų33.83%0.03118%0.177CC..Hα-helixtrans-65.5-38.3174.900000114.3Y432 V485 L486 K487 Y493Y432-G489 PolarHBondContact OH-O 3.46Å; V485-G489 PolarHBondContact O-N 3.21Å; L486-G489 PolarHBondContact O-N 2.87Å; K487-G489 VanDerWaalsContact C-N 3.26Å; K487-G489 PolarHBondContact O-N 3.46Å; G489-Y493 WeakPolarHBondContact O-CB 3.36Å; G489-Y493 PolarHBondContact O-N 2.63Å; G489-Y493 VanDerWaalsContact O-N 3.08Å
490A95.2Very high89Confident0 Ų030.8 Ų30.80%016%0.157CC..Hα-helixtrans-64.4-47.1174.900000111.5F391 I431 L486 K487 A492 Y493 V494F391-A490 HydrophobicContact CD2-CB 3.72Å; F391-A490 HydrophobicContact CE2-CB 3.45Å; F391-A490 VanDerWaalsContact CE2-CB 3.45Å; F391-A490 HydrophobicContact CZ-CB 4.1Å; I431-A490 HydrophobicContact CG2-CB 3.63Å; L486-A490 WeakPolarHBondContact O-CB 3.43Å; L486-A490 PolarHBondContact O-N 2.6Å; K487-A490 WeakPolarHBondContact O-CB 3.29Å; K487-A490 PolarHBondContact O-N 3.07Å; K487-A490 VanDerWaalsContact O-N 3.11Å; A490-A492 VanDerWaalsContact C-N 3.35Å; A490-A492 PolarHBondContact O-N 3.16Å; A490-Y493 PolarHBondContact O-N 2.96Å; A490-V494 WeakPolarHBondContact O-CB 3.32Å; A490-V494 WeakPolarHBondContact O-CG2 3.39Å; A490-V494 PolarHBondContact O-N 3.27Å
491I91.5Very high89.3Confident35 Ų3534.9 Ų34.918%0.17918%0.175CC..Hα-helixtrans-57.1-49.1176-66.5163000110.2F391 D482 K487 A488 Y493 V494 N495F391-I491 HydrophobicContact CB-CG1 4Å; F391-I491 HydrophobicContact CD1-CD1 4.08Å; F391-I491 HydrophobicContact CD1-CG1 3.43Å; F391-I491 VanDerWaalsContact CD1-CG1 3.43Å; F391-I491 HydrophobicContact CE1-CD1 4.42Å; F391-I491 HydrophobicContact CE1-CG1 4.07Å; F391-I491 HydrophobicContact CG-CG1 3.8Å; D482-I491 HydrophobicContact CB-CD1 4.26Å; K487-I491 VanDerWaalsContact O-CG1 3.28Å; K487-I491 WeakPolarHBondContact O-CG1 3.32Å; K487-I491 PolarHBondContact O-N 3.45Å; A488-I491 PolarHBondContact O-N 2.86Å; I491-Y493 VanDerWaalsContact C-N 3.31Å; I491-Y493 PolarHBondContact O-N 3.38Å; I491-V494 PolarHBondContact O-N 3.21Å; I491-N495 WeakPolarHBondContact O-CB 3.43Å; I491-N495 PolarHBondContact O-N 2.72Å; I491-N495 PolarHBondContact O-ND2 3.3Å
492A89.1Confident89.4Confident0 Ų032 Ų320%016%0.16CC..Hα-helixtrans-57.3-46.5179.400000111.4V463 V465 A478 A488 A490 N495 A496V463-A492 HydrophobicContact CB-CB 4.49Å; V463-A492 HydrophobicContact CG1-CB 4.3Å; V465-A492 HydrophobicContact CG1-CB 4.04Å; V465-A492 HydrophobicContact CG2-CB 3.95Å; A478-A492 VanDerWaalsContact CB-O 3.28Å; A478-A492 WeakPolarHBondContact CB-O 3.11Å; A488-A492 WeakPolarHBondContact O-CB 3.33Å; A488-A492 PolarHBondContact O-N 2.98Å; A490-A492 VanDerWaalsContact C-N 3.35Å; A490-A492 PolarHBondContact O-N 3.16Å; A492-N495 PolarHBondContact O-N 3.48Å; A492-A496 PolarHBondContact O-N 2.7Å
493Y94.3Very high89.1Confident5 Ų529.8 Ų29.82%0.0215%0.148CC..Hα-helixtrans-75.5-35-175.1-162.2-107.8000113.6Y432 V435 D436 V443 L445 I467 G489 A490 I491 A496 N497Y432-Y493 AromaticContact CD1-CD1 3.48Å; Y432-Y493 HydrophobicContact CD1-CD1 3.48Å; Y432-Y493 VanDerWaalsContact CD1-CD1 3.48Å; Y432-Y493 HydrophobicContact CD1-CD2 4.15Å; Y432-Y493 HydrophobicContact CD1-CE1 4.01Å; Y432-Y493 AromaticContact CD1-CG 3.57Å; Y432-Y493 HydrophobicContact CD1-CG 3.57Å; Y432-Y493 HydrophobicContact CD2-CD1 4.03Å; Y432-Y493 AromaticContact CD2-CD2 3.61Å; Y432-Y493 HydrophobicContact CD2-CD2 3.61Å; Y432-Y493 AromaticContact CD2-CE1 3.92Å; Y432-Y493 HydrophobicContact CD2-CE1 3.92Å; Y432-Y493 AromaticContact CD2-CE2 3.46Å; Y432-Y493 HydrophobicContact CD2-CE2 3.46Å; Y432-Y493 VanDerWaalsContact CD2-CE2 3.46Å; Y432-Y493 AromaticContact CD2-CG 3.89Å; Y432-Y493 HydrophobicContact CD2-CG 3.89Å; Y432-Y493 AromaticContact CD2-CZ 3.65Å; Y432-Y493 AromaticContact CE1-CD1 3.92Å; Y432-Y493 HydrophobicContact CE1-CD1 3.92Å; Y432-Y493 AromaticContact CE1-CD2 3.95Å; Y432-Y493 HydrophobicContact CE1-CD2 3.95Å; Y432-Y493 AromaticContact CE1-CG 3.49Å; Y432-Y493 HydrophobicContact CE1-CG 3.49Å; Y432-Y493 VanDerWaalsContact CE1-CG 3.49Å; Y432-Y493 HydrophobicContact CE2-CD1 4.41Å; Y432-Y493 AromaticContact CE2-CD2 3.37Å; Y432-Y493 HydrophobicContact CE2-CD2 3.37Å; Y432-Y493 AromaticContact CE2-CE2 3.63Å; Y432-Y493 HydrophobicContact CE2-CE2 3.63Å; Y432-Y493 AromaticContact CE2-CG 3.81Å; Y432-Y493 HydrophobicContact CE2-CG 3.81Å; Y432-Y493 AromaticContact CG-CD1 3.54Å; Y432-Y493 HydrophobicContact CG-CD1 3.54Å; Y432-Y493 HydrophobicContact CG-CD2 4Å; Y432-Y493 AromaticContact CG-CE1 3.56Å; Y432-Y493 HydrophobicContact CG-CE1 3.56Å; Y432-Y493 HydrophobicContact CG-CE2 4Å; Y432-Y493 AromaticContact CG-CG 3.78Å; Y432-Y493 HydrophobicContact CG-CG 3.78Å; Y432-Y493 AromaticContact CG-CZ 3.81Å; Y432-Y493 AromaticContact CZ-CD2 3.56Å; Y432-Y493 AromaticContact CZ-CG 3.61Å; V435-Y493 HydrophobicContact CB-CD1 3.83Å; V435-Y493 HydrophobicContact CB-CE1 4.16Å; V435-Y493 HydrophobicContact CG1-CD1 3.66Å; V435-Y493 HydrophobicContact CG1-CE1 4.08Å; V435-Y493 HydrophobicContact CG2-CD1 4.34Å; D436-Y493 WeakPolarHBondContact OD1-CE1 3.43Å; D436-Y493 PolarHBondContact OD1-OH 2.87Å; D436-Y493 PolarHBondContact OD2-OH 3.41Å; V443-Y493 VanDerWaalsContact CG2-OH 3.32Å; V443-Y493 WeakPolarHBondContact CG2-OH 3.49Å; L445-Y493 HydrophobicContact CD1-CD2 4.37Å; L445-Y493 HydrophobicContact CD1-CE2 4.16Å; I467-Y493 HydrophobicContact CG2-CD2 3.85Å; I467-Y493 HydrophobicContact CG2-CE2 3.53Å; G489-Y493 WeakPolarHBondContact O-CB 3.36Å; G489-Y493 PolarHBondContact O-N 2.63Å; G489-Y493 VanDerWaalsContact O-N 3.08Å; A490-Y493 PolarHBondContact O-N 2.96Å; I491-Y493 VanDerWaalsContact C-N 3.31Å; I491-Y493 PolarHBondContact O-N 3.38Å; Y493-A496 PolarHBondContact O-N 3.24Å; Y493-N497 WeakPolarHBondContact CD1-ND2 3.36Å; Y493-N497 WeakPolarHBondContact CE1-ND2 3.41Å; Y493-N497 WeakPolarHBondContact O-CB 3.23Å; Y493-N497 PolarHBondContact O-N 2.61Å; Y493-N497 PolarHBondContact O-ND2 3.39Å
494V93Very high89Confident1 Ų125.9 Ų25.91%0.00613%0.133CC..Hα-helixtrans-60.6-47.5169.8163.90000110.5F391 M410 V435 F439 A490 I491 A496 N497 A498F391-V494 HydrophobicContact CB-CG2 4.36Å; M410-V494 HydrophobicContact CE-CG1 3.71Å; M410-V494 HydrophobicContact CE-CG2 4.1Å; M410-V494 HydrophobicContact SD-CG2 3.96Å; V435-V494 HydrophobicContact CG1-CG2 3.97Å; V435-V494 HydrophobicContact CG2-CG2 3.75Å; F439-V494 HydrophobicContact CE2-CG1 4.33Å; F439-V494 HydrophobicContact CZ-CG1 4.27Å; A490-V494 WeakPolarHBondContact O-CB 3.32Å; A490-V494 WeakPolarHBondContact O-CG2 3.39Å; A490-V494 PolarHBondContact O-N 3.27Å; I491-V494 PolarHBondContact O-N 3.21Å; V494-A496 VanDerWaalsContact C-N 3.32Å; V494-A496 PolarHBondContact O-N 3.45Å; V494-N497 PolarHBondContact O-N 3.36Å; V494-A498 WeakPolarHBondContact O-CB 3.48Å; V494-A498 PolarHBondContact O-N 2.89Å
495N86.7Confident88.6Confident61 Ų6125.9 Ų25.933%0.32614%0.142SC..Hα-helixtrans-60.7-42.7178.5-71.6-18.6000111.5A478 S479 I491 A492 A498 F499A478-N495 HydrophobicContact CB-CB 3.78Å; S479-N495 PolarHBondContact O-ND2 2.89Å; I491-N495 WeakPolarHBondContact O-CB 3.43Å; I491-N495 PolarHBondContact O-N 2.72Å; I491-N495 PolarHBondContact O-ND2 3.3Å; A492-N495 PolarHBondContact O-N 3.48Å; N495-A498 PolarHBondContact O-N 3.35Å; N495-F499 VanDerWaalsContact O-CD2 3.28Å; N495-F499 WeakPolarHBondContact O-CD2 3.48Å; N495-F499 PolarHBondContact O-N 2.95Å
496A86.6Confident87.6Confident0 Ų025.3 Ų25.30%015%0.149CC..Hα-helixtrans-63.4-46.6177.100000111.9V465 I467 A478 A492 Y493 V494 A498 F499 V500V465-A496 HydrophobicContact CG2-CB 3.92Å; I467-A496 VanDerWaalsContact CD1-C 3.44Å; I467-A496 HydrophobicContact CD1-CB 3.46Å; I467-A496 VanDerWaalsContact CD1-CB 3.46Å; I467-A496 HydrophobicContact CG1-CB 3.78Å; I467-A496 HydrophobicContact CG2-CB 4.17Å; A478-A496 HydrophobicContact CB-CB 3.81Å; A492-A496 PolarHBondContact O-N 2.7Å; Y493-A496 PolarHBondContact O-N 3.24Å; V494-A496 VanDerWaalsContact C-N 3.32Å; V494-A496 PolarHBondContact O-N 3.45Å; A496-A498 VanDerWaalsContact C-N 3.33Å; A496-A498 PolarHBondContact O-N 2.89Å; A496-F499 WeakPolarHBondContact O-CB 3.44Å; A496-F499 PolarHBondContact O-N 3.08Å; A496-F499 VanDerWaalsContact O-N 3.15Å; A496-V500 PolarHBondContact O-N 3.3Å
497N91.4Very high86.2Confident0 Ų028.4 Ų28.40%016%0.163CC..Hα-helixtrans-64.5-34.6177.5-90.9-84.5000112.8V435 F439 Q441 Y493 V494 F499 V500 Q501V435-N497 HydrophobicContact CG1-CB 4.27Å; F439-N497 HydrophobicContact CB-CB 4.49Å; F439-N497 HydrophobicContact CD1-CB 4.27Å; F439-N497 HydrophobicContact CD2-CB 3.4Å; F439-N497 HydrophobicContact CE1-CB 4.36Å; F439-N497 HydrophobicContact CE2-CB 3.51Å; F439-N497 HydrophobicContact CG-CB 3.81Å; F439-N497 HydrophobicContact CZ-CB 4.01Å; Q441-N497 VanDerWaalsContact NE2-CB 3.33Å; Q441-N497 PolarHBondContact NE2-O 2.9Å; Q441-N497 PolarHBondContact NE2-OD1 2.91Å; Y493-N497 WeakPolarHBondContact CD1-ND2 3.36Å; Y493-N497 WeakPolarHBondContact CE1-ND2 3.41Å; Y493-N497 WeakPolarHBondContact O-CB 3.23Å; Y493-N497 PolarHBondContact O-N 2.61Å; Y493-N497 PolarHBondContact O-ND2 3.39Å; V494-N497 PolarHBondContact O-N 3.36Å; N497-F499 PolarHBondContact O-N 3.38Å; N497-V500 WeakPolarHBondContact O-CB 3.34Å; N497-V500 PolarHBondContact O-N 3.37Å; N497-V500 VanDerWaalsContact O-N 3.1Å; N497-Q501 PolarHBondContact O-N 3.4Å
498A87.9Confident84.5Confident7 Ų725.9 Ų25.96%0.05815%0.152CC..Hα-helixtrans-60.5-34.2174.200000111.9F439 V494 N495 A496 Q501 K502F439-A498 HydrophobicContact CE1-CB 4.19Å; F439-A498 HydrophobicContact CZ-CB 4.18Å; V494-A498 WeakPolarHBondContact O-CB 3.48Å; V494-A498 PolarHBondContact O-N 2.89Å; N495-A498 PolarHBondContact O-N 3.35Å; A496-A498 VanDerWaalsContact C-N 3.33Å; A496-A498 PolarHBondContact O-N 2.89Å; A498-Q501 PolarHBondContact O-N 3.36Å; A498-K502 WeakPolarHBondContact O-CG 3.17Å; A498-K502 PolarHBondContact O-N 2.93Å; A498-K502 VanDerWaalsContact O-N 3.16Å
499F82.9Confident82.5Confident48 Ų4826.8 Ų26.821%0.21116%0.161CC..Hα-helixtrans-68.1-40.5172.7-59.1-45000112.5I383 F476 A478 N495 A496 N497 Q501 K502 E503 I508I383-F499 HydrophobicContact CG2-CD1 3.48Å; I383-F499 VanDerWaalsContact CG2-CD1 3.48Å; I383-F499 HydrophobicContact CG2-CE1 3.04Å; I383-F499 HydrophobicContact CG2-CZ 3.94Å; F476-F499 HydrophobicContact CB-CB 4.29Å; F476-F499 HydrophobicContact CB-CD2 4.36Å; F476-F499 HydrophobicContact CD1-CB 3.31Å; F476-F499 HydrophobicContact CD1-CD2 4.31Å; F476-F499 HydrophobicContact CD1-CG 4.09Å; F476-F499 HydrophobicContact CE1-CB 3.67Å; F476-F499 HydrophobicContact CG-CB 3.8Å; F476-F499 HydrophobicContact CZ-CB 4.41Å; A478-F499 HydrophobicContact CB-CE2 4.3Å; N495-F499 VanDerWaalsContact O-CD2 3.28Å; N495-F499 WeakPolarHBondContact O-CD2 3.48Å; N495-F499 PolarHBondContact O-N 2.95Å; A496-F499 WeakPolarHBondContact O-CB 3.44Å; A496-F499 PolarHBondContact O-N 3.08Å; A496-F499 VanDerWaalsContact O-N 3.15Å; N497-F499 PolarHBondContact O-N 3.38Å; F499-Q501 VanDerWaalsContact C-N 3.32Å; F499-Q501 PolarHBondContact O-N 2.87Å; F499-K502 PolarHBondContact O-N 3.35Å; F499-E503 PolarHBondContact O-N 3.12Å; F499-I508 WeakPolarHBondContact O-CD1 3.28Å
500V86.1Confident80.2Confident0 Ų032.9 Ų32.90%019%0.187CC..Hα-helixtrans-62.4-41.4175.2179.20000111.1Q441 V443 I467 N469 F476 A496 N497 K502 E503 N504Q441-V500 HydrophobicContact CG-CG1 4.19Å; Q441-V500 VanDerWaalsContact OE1-CG1 3.25Å; V443-V500 HydrophobicContact CG1-CB 4.19Å; V443-V500 HydrophobicContact CG1-CG1 3.78Å; V443-V500 HydrophobicContact CG1-CG2 3.82Å; I467-V500 HydrophobicContact CD1-CG2 3.69Å; I467-V500 HydrophobicContact CG1-CG2 4.17Å; N469-V500 HydrophobicContact CB-CG1 3.89Å; N469-V500 HydrophobicContact CB-CG2 4.28Å; F476-V500 HydrophobicContact CD2-CG2 3.43Å; F476-V500 VanDerWaalsContact CD2-CG2 3.43Å; F476-V500 HydrophobicContact CE2-CB 4.39Å; F476-V500 HydrophobicContact CE2-CG2 3.68Å; F476-V500 HydrophobicContact CG-CG2 4.32Å; A496-V500 PolarHBondContact O-N 3.3Å; N497-V500 WeakPolarHBondContact O-CB 3.34Å; N497-V500 PolarHBondContact O-N 3.37Å; N497-V500 VanDerWaalsContact O-N 3.1Å; V500-K502 VanDerWaalsContact C-N 3.32Å; V500-K502 PolarHBondContact O-N 3.23Å; V500-E503 WeakPolarHBondContact O-CB 3.4Å; V500-E503 PolarHBondContact O-N 3.39Å; V500-E503 VanDerWaalsContact O-N 3.11Å; V500-N504 PolarHBondContact O-N 3.01Å; V500-N504 PolarHBondContact O-ND2 2.64Å
501Q86.7Confident77.7Confident89 Ų8934.5 Ų34.542%0.41620%0.2SC..Hα-helixtrans-61-43177.8-174.9-178.942.100111.2F439 Q441 N497 A498 F499 E503 N504 A505F439-Q501 HydrophobicContact CD1-CB 4.03Å; F439-Q501 HydrophobicContact CD1-CG 4.43Å; F439-Q501 HydrophobicContact CE1-CB 4.37Å; Q441-Q501 VanDerWaalsContact OE1-N 3.1Å; N497-Q501 PolarHBondContact O-N 3.4Å; A498-Q501 PolarHBondContact O-N 3.36Å; F499-Q501 VanDerWaalsContact C-N 3.32Å; F499-Q501 PolarHBondContact O-N 2.87Å; Q501-E503 VanDerWaalsContact C-N 3.32Å; Q501-E503 PolarHBondContact O-N 2.82Å; Q501-N504 PolarHBondContact O-N 2.96Å; Q501-A505 WeakPolarHBondContact O-CB 3.44Å; Q501-A505 PolarHBondContact O-N 3.34Å
502K80.4Confident75.3Confident17 Ų1735.8 Ų35.87%0.07421%0.21CC..Hα-helixtrans-62.1-38.5174.6-73.4-170.2171.2-160.20112.2E384 A498 F499 V500 A505 G506 E507 I508E384-K502 PolarHBondContact O-NZ 3.16Å; A498-K502 WeakPolarHBondContact O-CG 3.17Å; A498-K502 PolarHBondContact O-N 2.93Å; A498-K502 VanDerWaalsContact O-N 3.16Å; F499-K502 PolarHBondContact O-N 3.35Å; V500-K502 VanDerWaalsContact C-N 3.32Å; V500-K502 PolarHBondContact O-N 3.23Å; K502-A505 PolarHBondContact O-N 2.69Å; K502-G506 PolarHBondContact O-N 3.04Å; K502-E507 HydrophobicContact CB-CB 4.22Å; K502-E507 WeakPolarHBondContact CG-OE2 3.4Å; K502-E507 WeakPolarHBondContact O-CA 3.42Å; K502-E507 WeakPolarHBondContact O-CB 3.34Å; K502-E507 PolarHBondContact O-N 3.44Å; K502-I508 HydrophobicContact CB-CD1 3.59Å; K502-I508 HydrophobicContact CB-CG1 3.92Å; K502-I508 HydrophobicContact CD-CD1 4.48Å; K502-I508 PolarHBondContact O-N 2.82Å
503E80.6Confident72.9Confident0 Ų038.1 Ų38.10%023%0.226CC..Hα-helixtrans-64.1-44.8172.9-170.1-175-152.200112.3N469 T472 T474 F476 F499 V500 Q501 A505 G506 I508N469-E503 WeakPolarHBondContact CB-OE2 3.3Å; N469-E503 PolarHBondContact ND2-OE2 3.17Å; T472-E503 WeakPolarHBondContact CB-OE1 3.43Å; T472-E503 HydrophobicContact CG2-CG 4.29Å; T472-E503 PolarHBondContact OG1-OE1 3.19Å; T472-E503 PolarHBondContact OG1-OE2 3.24Å; T474-E503 WeakPolarHBondContact CB-OE1 3.41Å; T474-E503 PolarHBondContact OG1-OE1 2.96Å; F476-E503 WeakPolarHBondContact CE2-OE2 3.44Å; F476-E503 HydrophobicContact CZ-CB 3.99Å; F476-E503 HydrophobicContact CZ-CG 4.42Å; F476-E503 WeakPolarHBondContact CZ-OE2 3.36Å; F499-E503 PolarHBondContact O-N 3.12Å; V500-E503 WeakPolarHBondContact O-CB 3.4Å; V500-E503 PolarHBondContact O-N 3.39Å; V500-E503 VanDerWaalsContact O-N 3.11Å; Q501-E503 VanDerWaalsContact C-N 3.32Å; Q501-E503 PolarHBondContact O-N 2.82Å; E503-A505 VanDerWaalsContact C-N 3.3Å; E503-A505 PolarHBondContact O-N 3.31Å; E503-G506 PolarHBondContact O-N 3.28Å; E503-I508 WeakPolarHBondContact CA-O 3.23Å; E503-I508 HydrophobicContact CB-CB 3.86Å; E503-I508 HydrophobicContact CB-CG2 4.05Å; E503-I508 HydrophobicContact CG-CB 4.3Å; E503-I508 HydrophobicContact CG-CG2 4.12Å
504N82.5Confident70.1Confident55 Ų5545.3 Ų45.329%0.29426%0.257SS..Hα-helixtrans-65.8-33.9178.9-70.8-21000112.4Q441 N469 V500 Q501 G506Q441-N504 PolarHBondContact OE1-ND2 3.45Å; N469-N504 PolarHBondContact ND2-OD1 3.3Å; V500-N504 PolarHBondContact O-N 3.01Å; V500-N504 PolarHBondContact O-ND2 2.64Å; Q501-N504 PolarHBondContact O-N 2.96Å; N504-G506 PolarHBondContact O-N 3.48Å
505A81.2Confident67.5Low68 Ų6854.7 Ų54.756%0.56229%0.293SS*.THydrogen-bonded Turntrans-71.2-7.2172.600000113.6Q501 K502 E503 E507Q501-A505 WeakPolarHBondContact O-CB 3.44Å; Q501-A505 PolarHBondContact O-N 3.34Å; K502-A505 PolarHBondContact O-N 2.69Å; E503-A505 VanDerWaalsContact C-N 3.3Å; E503-A505 PolarHBondContact O-N 3.31Å; A505-E507 HydrophobicContact CB-CG 4.13Å; A505-E507 PolarHBondContact O-N 2.93Å
506G71.3Confident65.7Low51 Ų5157.4 Ų57.453%0.52631%0.307SS..THydrogen-bonded Turntrans73.111.9-175.500000113.4K502 E503 N504K502-G506 PolarHBondContact O-N 3.04Å; E503-G506 PolarHBondContact O-N 3.28Å; N504-G506 PolarHBondContact O-N 3.48Å
507E65.9Low63.5Low104 Ų10461.8 Ų61.849%0.48633%0.334SS..SBendtrans-70-44.1168-60.1178.5-16500107.9T381 K502 A505T381-E507 WeakPolarHBondContact CB-O 3.49Å; T381-E507 HydrophobicContact CG2-CB 3.58Å; T381-E507 WeakPolarHBondContact CG2-O 3.45Å; T381-E507 VanDerWaalsContact OG1-C 3.3Å; T381-E507 PolarHBondContact OG1-O 3.35Å; K502-E507 HydrophobicContact CB-CB 4.22Å; K502-E507 WeakPolarHBondContact CG-OE2 3.4Å; K502-E507 WeakPolarHBondContact O-CA 3.42Å; K502-E507 WeakPolarHBondContact O-CB 3.34Å; K502-E507 PolarHBondContact O-N 3.44Å; A505-E507 HydrophobicContact CB-CG 4.13Å; A505-E507 PolarHBondContact O-N 2.93Å
508I57.1Low60.9Low0 Ų066.8 Ų66.80%037%0.366CS..SBendtrans-98.6140.3170.7-58.7168.3000109.3A376 T381 F476 F499 K502 E503A376-I508 HydrophobicContact CB-CB 4.5Å; A376-I508 HydrophobicContact CB-CG1 4.14Å; A376-I508 HydrophobicContact CB-CG2 3.79Å; T381-I508 HydrophobicContact CG2-CG1 3.94Å; T381-I508 VanDerWaalsContact OG1-CA 3.3Å; T381-I508 WeakPolarHBondContact OG1-CA 3.45Å; T381-I508 WeakPolarHBondContact OG1-CG1 3.44Å; F476-I508 HydrophobicContact CE1-CD1 4.29Å; F476-I508 HydrophobicContact CZ-CG2 4.49Å; F499-I508 WeakPolarHBondContact O-CD1 3.28Å; K502-I508 HydrophobicContact CB-CD1 3.59Å; K502-I508 HydrophobicContact CB-CG1 3.92Å; K502-I508 HydrophobicContact CD-CD1 4.48Å; K502-I508 PolarHBondContact O-N 2.82Å; E503-I508 WeakPolarHBondContact CA-O 3.23Å; E503-I508 HydrophobicContact CB-CB 3.86Å; E503-I508 HydrophobicContact CB-CG2 4.05Å; E503-I508 HydrophobicContact CG-CB 4.3Å; E503-I508 HydrophobicContact CG-CG2 4.12Å
509G48.3Very low58.6Low19 Ų1973.4 Ų73.420%0.19641%0.406CS..PPolyproline II helixtrans-78.5131.3-163.200000110.3
510K44.9Very low56.4Low130 Ų13082 Ų8257%0.56545%0.454SS*.PPolyproline II helixtrans-66.6147178.7-63.7-175.6178.7-174.30110.8V512K510-V512 PolarHBondContact O-N 3.46Å
511A43.1Very low54.9Low34 Ų3486.1 Ų86.128%0.28148%0.477SS..PPolyproline II helixtrans-58.5127.716400000109.6T472 S513T472-A511 WeakPolarHBondContact O-CB 3.25Å; A511-S513 PolarHBondContact O-N 3.29Å
512V42.3Very low53.2Low63 Ų6385.9 Ų85.938%0.38248%0.48SS..  trans-80.8114.8176.2-174.10000107.5K510 D516K510-V512 PolarHBondContact O-N 3.46Å; V512-D516 HydrophobicContact CG1-CB 4.47Å
513S37.2Very low51.7Low49 Ų4989.8 Ų89.834%0.34350%0.503SS..  trans-67.3141.5173.9166.60000110.1A511 R515 D516A511-S513 PolarHBondContact O-N 3.29Å; S513-R515 PolarHBondContact O-N 2.8Å; S513-R515 PolarHBondContact OG-N 3.27Å; S513-D516 PolarHBondContact O-N 3.21Å
514F36.4Very low50Low155 Ų15595.1 Ų95.168%0.6853%0.532SS*.THydrogen-bonded Turntrans-52.6-16173.576.4-88000114.2
515R38.5Very low48Very low198 Ų19897.6 Ų97.675%0.74755%0.547SS*.THydrogen-bonded Turntrans-84.1-16.9177.2-66.6-175.2171.1168.1-1.3114.3S513S513-R515 PolarHBondContact O-N 2.8Å; S513-R515 PolarHBondContact OG-N 3.27Å
516D48.1Very low45.8Very low119 Ų11999.5 Ų99.564%0.63655%0.546SS*.SBendtrans-99.84.9-174.8-61.5-39.4000112.9V512 S513 P518V512-D516 HydrophobicContact CG1-CB 4.47Å; S513-D516 PolarHBondContact O-N 3.21Å; D516-P518 WeakPolarHBondContact O-CD 3.38Å
517V40.2Very low43.9Very low91 Ų91103 Ų10355%0.55255%0.548SS*.SBendtrans-82.6120.3174.4-170.10000109.3T519V517-T519 PolarHBondContact O-N 2.9Å
518P37.6Very low42.3Very low105 Ų105102.9 Ų102.968%0.68255%0.553SS**  trans-58.7125.4172-18.630.2000109.7D516 N520D516-P518 WeakPolarHBondContact O-CD 3.38Å; P518-N520 VanDerWaalsContact C-N 3.34Å; P518-N520 PolarHBondContact O-N 2.89Å
519T39Very low41Very low147 Ų147111.5 Ų111.590%0.90260%0.599SS**  trans-71.593167.831.80000108.2V517V517-T519 PolarHBondContact O-N 2.9Å
520N36.8Very low40.4Very low228 Ų228119.9 Ų119.9100%1.21964%0.635SS**  trans-111.90163.2-90.5-9.1000110.2P518P518-N520 VanDerWaalsContact C-N 3.34Å; P518-N520 PolarHBondContact O-N 2.89Å

Retrieved 520 of 520 residues in 389.2 ms (Link to these results)