A0A077ZII3_TRITR Loading...

glycerol kinase

AlphaFold DB , UniProt , Accession A0A077ZII3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 502 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M66.8Low94.2Very high176 Ų17635.6 Ų35.687%0.86718%0.181SC*.  0129.80-171.6174-86.500105.2Q72M1-Q72 HydrophobicContact CG-CG 4.09Å; M1-Q72 HydrophobicContact SD-CG 3.9Å
2E89.2Confident94Very high145 Ų14533.8 Ų33.868%0.67817%0.173SC*.  trans-68.4139.1175.9-70.3178.4163.900109.1Y4 Q72E2-Y4 HydrophobicContact CB-CE2 4.25Å; E2-Y4 PolarHBondContact OE2-OH 2.79Å; E2-Q72 PolarHBondContact O-NE2 3.19Å
3S96Very high93.6Very high18 Ų1834.8 Ų34.813%0.12618%0.182CC..  trans-121.3155-177.853.80000111Q72 E74 Y452S3-Q72 CarbonylContact C-O 3.59Å; S3-Q72 VanDerWaalsContact CA-O 3.3Å; S3-Q72 WeakPolarHBondContact CA-O 3.42Å; S3-E74 WeakPolarHBondContact CB-OE1 3.18Å; S3-E74 PolarHBondContact OG-OE1 3.23Å; S3-Y452 WeakPolarHBondContact O-CE2 3.47Å; S3-Y452 PolarHBondContact O-OH 3.13Å
4Y98.3Very high93.6Very high19 Ų1933 Ų338%0.07517%0.174CC..EExtended strand (participates in β ladder)trans-140.4161.1-168.6-52.6-81.2000111.9E2 V19 F20 D21 V27 L68 Q72 I73 E74E2-Y4 HydrophobicContact CB-CE2 4.25Å; E2-Y4 PolarHBondContact OE2-OH 2.79Å; Y4-V19 HydrophobicContact CD1-CG1 4.21Å; Y4-V19 HydrophobicContact CG-CG1 3.83Å; Y4-F20 WeakPolarHBondContact CA-O 3.32Å; Y4-F20 WeakPolarHBondContact CB-O 3.47Å; Y4-D21 HydrophobicContact CD1-CB 4.24Å; Y4-D21 HydrophobicContact CE1-CB 4.27Å; Y4-V27 HydrophobicContact CD1-CG2 3.87Å; Y4-V27 HydrophobicContact CE1-CB 4.49Å; Y4-V27 HydrophobicContact CE1-CG1 4.23Å; Y4-V27 HydrophobicContact CE1-CG2 3.75Å; Y4-L68 HydrophobicContact CD2-CD1 4.09Å; Y4-L68 HydrophobicContact CD2-CD2 4.12Å; Y4-L68 HydrophobicContact CE2-CD1 4.3Å; Y4-L68 HydrophobicContact CE2-CD2 3.52Å; Y4-L68 HydrophobicContact CE2-CG 4.49Å; Y4-L68 HydrophobicContact CG-CD1 4.37Å; Y4-Q72 HydrophobicContact CD2-CB 3.92Å; Y4-Q72 HydrophobicContact CE2-CB 4.2Å; Y4-Q72 PolarHBondContact N-O 3.22Å; Y4-I73 CarbonylContact O-C 3.4Å; Y4-I73 WeakPolarHBondContact O-CA 3.36Å; Y4-E74 PolarHBondContact O-N 3.27Å
5I98.5Very high93.9Very high0 Ų030.8 Ų30.80%016%0.162CC..EExtended strand (participates in β ladder)trans-107.6134.3168.3-64.2-63.2000108.9V19 F20 E74 A443 A446 V450 Y452 W453I5-V19 CarbonylContact O-C 3.54Å; I5-V19 WeakPolarHBondContact O-CA 3.32Å; I5-F20 PolarHBondContact N-O 3Å; I5-F20 PolarHBondContact O-N 3.29Å; I5-E74 HydrophobicContact CD1-CB 4.27Å; I5-A443 HydrophobicContact CG2-CB 3.83Å; I5-A446 HydrophobicContact CG2-CB 4.2Å; I5-V450 HydrophobicContact CD1-CG2 4.02Å; I5-Y452 HydrophobicContact CD1-CD1 4.31Å; I5-Y452 HydrophobicContact CD1-CD2 4.25Å; I5-Y452 HydrophobicContact CD1-CG 3.96Å; I5-Y452 HydrophobicContact CG1-CD1 3.55Å; I5-Y452 HydrophobicContact CG1-CD2 4.17Å; I5-Y452 HydrophobicContact CG1-CE1 3.85Å; I5-Y452 HydrophobicContact CG1-CE2 4.43Å; I5-Y452 HydrophobicContact CG1-CG 3.71Å; I5-W453 HydrophobicContact CG1-CH2 4.41Å; I5-W453 HydrophobicContact CG1-CZ3 4.3Å
6M98.7Very high94.2Very high0 Ų033.1 Ų33.10%017%0.168CC..EExtended strand (participates in β ladder)trans-101130.8173-179.5178.2-73.600109.8I18 V19 I59 L63 I73 G75 I76 G77 F231M6-I18 CarbonylContact C-O 3.5Å; M6-I18 WeakPolarHBondContact CA-O 3.5Å; M6-V19 HydrophobicContact CB-CG2 4.48Å; M6-V19 HydrophobicContact CE-CG2 3.92Å; M6-V19 HydrophobicContact CG-CG2 4.43Å; M6-I59 HydrophobicContact CE-CG2 4.23Å; M6-I59 HydrophobicContact SD-CG1 4.14Å; M6-I59 HydrophobicContact SD-CG2 4.04Å; M6-L63 HydrophobicContact CE-CD1 4.4Å; M6-L63 HydrophobicContact CE-CD2 3.74Å; M6-L63 HydrophobicContact CE-CG 3.87Å; M6-I73 HydrophobicContact CB-CD1 4.45Å; M6-I73 HydrophobicContact CB-CG2 3.78Å; M6-I73 HydrophobicContact CE-CD1 4.26Å; M6-I73 HydrophobicContact CE-CG1 4.29Å; M6-G75 PolarHBondContact N-O 3.17Å; M6-I76 HydrophobicContact CB-CG1 4.36Å; M6-I76 CarbonylContact O-C 3.58Å; M6-I76 VanDerWaalsContact O-CA 3.27Å; M6-I76 WeakPolarHBondContact O-CA 3.45Å; M6-G77 PolarHBondContact O-N 3.12Å; M6-F231 HydrophobicContact CE-CZ 4.09Å; M6-F231 HydrophobicContact SD-CE2 4.06Å; M6-F231 HydrophobicContact SD-CZ 4.08Å
7S98.7Very high94.4Very high0 Ų031.2 Ų31.20%016%0.158CC..EExtended strand (participates in β ladder)trans-103.5140.1165.863.90000110.2A17 I18 F20 G77 A439S7-A17 CarbonylContact O-C 3.39Å; S7-A17 VanDerWaalsContact O-CA 3.25Å; S7-A17 WeakPolarHBondContact O-CA 3.42Å; S7-I18 PolarHBondContact N-O 3.27Å; S7-I18 PolarHBondContact O-N 2.87Å; S7-I18 WeakPolarHBondContact OG-CB 3.02Å; S7-I18 PolarHBondContact OG-O 2.77Å; S7-F20 WeakPolarHBondContact OG-CE2 3.2Å; S7-G77 CarbonylContact C-O 3.6Å; S7-G77 WeakPolarHBondContact CA-O 3.42Å; S7-A439 VanDerWaalsContact CB-O 3.25Å; S7-A439 WeakPolarHBondContact CB-O 3.44Å
8I98.8Very high94.7Very high0 Ų029.7 Ų29.70%015%0.151CC..EExtended strand (participates in β ladder)trans-112.9118168.4-61.7167.1000107.1R16 V55 I59 I76 G77 I78 T79 L168 L172I8-R16 WeakPolarHBondContact CA-O 3.19Å; I8-V55 HydrophobicContact CD1-CG1 4.34Å; I8-V55 HydrophobicContact CG2-CG1 3.83Å; I8-V55 HydrophobicContact CG2-CG2 4.26Å; I8-I59 HydrophobicContact CD1-CD1 3.67Å; I8-I59 HydrophobicContact CD1-CG1 4.09Å; I8-I59 HydrophobicContact CG1-CD1 4.36Å; I8-I59 HydrophobicContact CG1-CG1 4.23Å; I8-I76 HydrophobicContact CD1-CG2 3.76Å; I8-I76 HydrophobicContact CG1-CG2 4.26Å; I8-G77 PolarHBondContact N-O 2.99Å; I8-I78 HydrophobicContact CD1-CG1 4.47Å; I8-T79 WeakPolarHBondContact O-CG2 3.38Å; I8-T79 PolarHBondContact O-N 3.46Å; I8-T79 VanDerWaalsContact O-O 3.14Å; I8-L168 HydrophobicContact CG2-CD1 4.36Å; I8-L172 HydrophobicContact CD1-CD1 4.14Å
9D98.3Very high94.9Very high20 Ų2028.2 Ų28.211%0.10714%0.143CC..EExtended strand (participates in β ladder)trans-111.3102.4175.6175.519.1000109.8G11 S15 R16 T79 A439D9-G11 PolarHBondContact O-N 2.66Å; D9-S15 CarbonylContact O-C 3.29Å; D9-S15 WeakPolarHBondContact O-CA 3.45Å; D9-R16 HydrophobicContact CB-CB 4.28Å; D9-R16 PolarHBondContact N-O 2.63Å; D9-R16 PolarHBondContact O-N 3.39Å; D9-T79 WeakPolarHBondContact CA-O 3.48Å; D9-T79 HydrophobicContact CB-CG2 3.52Å; D9-A439 HydrophobicContact CB-CB 4.49Å
10Q98.6Very high95Very high0 Ų026.8 Ų26.80%014%0.136CC..EExtended strand (participates in β ladder)trans-9186.3175.9-158-74.660.200109I51 V55 T79 N80 Q81 I164 L168Q10-I51 HydrophobicContact CG-CG2 3.8Å; Q10-V55 HydrophobicContact CG-CG2 4.17Å; Q10-T79 PolarHBondContact N-O 2.85Å; Q10-N80 HydrophobicContact CB-CB 4.4Å; Q10-N80 CarbonylContact O-C 3.58Å; Q10-N80 VanDerWaalsContact O-CA 3.31Å; Q10-N80 WeakPolarHBondContact O-CA 3.38Å; Q10-Q81 PolarHBondContact O-N 2.9Å; Q10-I164 HydrophobicContact CB-CG2 3.88Å; Q10-I164 HydrophobicContact CG-CG2 3.74Å; Q10-L168 HydrophobicContact CB-CD1 3.86Å; Q10-L168 HydrophobicContact CG-CD1 4.18Å
11G94.8Very high95Very high14 Ų1427.6 Ų27.614%0.14414%0.141CC..  trans-82.5169.1178.100000113.4D9 T13 S14 F34D9-G11 PolarHBondContact O-N 2.66Å; G11-T13 VanDerWaalsContact C-N 3.31Å; G11-T13 PolarHBondContact O-N 2.92Å; G11-S14 WeakPolarHBondContact CA-O 3.22Å; G11-S14 PolarHBondContact N-O 3.44Å; G11-F34 WeakPolarHBondContact O-CE1 3.39Å; G11-F34 WeakPolarHBondContact O-CZ 3.32Å
12T91.5Very high96.3Very high13 Ų1324.8 Ų24.88%0.0812%0.124CC..SBendtrans-58.6-36-173.9-49.20000114.7F34 Q36 H46 V101 W102T12-F34 VanDerWaalsContact O-CE2 3.28Å; T12-F34 WeakPolarHBondContact O-CE2 3.36Å; T12-F34 WeakPolarHBondContact O-CZ 3.3Å; T12-Q36 PolarHBondContact O-NE2 3.16Å; T12-Q36 VanDerWaalsContact O-NE2 3.09Å; T12-Q36 PolarHBondContact O-OE1 3.29Å; T12-H46 PolarHBondContact O-CE1 2.85Å; T12-H46 PolarHBondContact O-NE2 2.97Å; T12-V101 HydrophobicContact CG2-CG1 4.16Å; T12-W102 HydrophobicContact CG2-CZ2 4.43Å; T12-W102 PolarHBondContact OG1-NE1 3.03Å
13T89.1Confident96.4Very high47 Ų4720.1 Ų20.129%0.28811%0.11SC..SBendtrans-111.9-12.5-175.358.50000113.9G11 E33 F34G11-T13 VanDerWaalsContact C-N 3.31Å; G11-T13 PolarHBondContact O-N 2.92Å; T13-E33 WeakPolarHBondContact O-CA 3.49Å; T13-F34 PolarHBondContact O-N 2.9Å
14S93.4Very high96.1Very high10 Ų1019.9 Ų19.97%0.0711%0.11CC..EExtended strand (participates in β ladder)trans-159.5147.7-176.265.10000111.4G11 Q31 K32G11-S14 WeakPolarHBondContact CA-O 3.22Å; G11-S14 PolarHBondContact N-O 3.44Å; S14-Q31 PolarHBondContact OG-NE2 3.41Å; S14-K32 CarbonylContact C-O 3.46Å; S14-K32 VanDerWaalsContact CA-O 3.23Å; S14-K32 WeakPolarHBondContact CA-O 3.32Å; S14-K32 WeakPolarHBondContact CB-O 3.25Å
15S98.2Very high95.9Very high0 Ų025.4 Ų25.40%014%0.135CC..EExtended strand (participates in β ladder)trans-92.1149.6166.9-61.70000110.5D9 Q31 K32 S54D9-S15 CarbonylContact O-C 3.29Å; D9-S15 WeakPolarHBondContact O-CA 3.45Å; S15-Q31 WeakPolarHBondContact O-CA 3.35Å; S15-K32 PolarHBondContact N-O 3.08Å; S15-K32 PolarHBondContact O-N 3.31Å; S15-S54 WeakPolarHBondContact CB-OG 3.41Å; S15-S54 PolarHBondContact OG-OG 3.31Å
16R98.1Very high95.8Very high68 Ų6829.3 Ų29.326%0.25715%0.153SC..EExtended strand (participates in β ladder)trans-134.9146.1174.3-66.8173.6179.4-169.9-12.3110.5I8 D9 S30 Q31I8-R16 WeakPolarHBondContact CA-O 3.19Å; D9-R16 HydrophobicContact CB-CB 4.28Å; D9-R16 PolarHBondContact N-O 2.63Å; D9-R16 PolarHBondContact O-N 3.39Å; R16-S30 CarbonylContact C-O 3.58Å; R16-S30 WeakPolarHBondContact CA-O 3.44Å; R16-Q31 HydrophobicContact CG-CB 3.87Å; R16-Q31 HydrophobicContact CG-CG 3.66Å; R16-Q31 VanDerWaalsContact NE-NE2 3.15Å; R16-Q31 VanDerWaalsContact NH2-NE2 3.11Å
17A98.6Very high95.7Very high0 Ų032 Ų320%017%0.169CC..EExtended strand (participates in β ladder)trans-125.2136.1162.300000108.6S7 S29 S30 V58 I59S7-A17 CarbonylContact O-C 3.39Å; S7-A17 VanDerWaalsContact O-CA 3.25Å; S7-A17 WeakPolarHBondContact O-CA 3.42Å; A17-S29 CarbonylContact O-C 3.55Å; A17-S29 WeakPolarHBondContact O-CA 3.41Å; A17-S30 PolarHBondContact N-O 3.31Å; A17-S30 PolarHBondContact O-N 3.35Å; A17-V58 HydrophobicContact CB-CB 4.04Å; A17-V58 HydrophobicContact CB-CG2 3.88Å; A17-V58 WeakPolarHBondContact CB-O 3.5Å; A17-I59 HydrophobicContact CB-CG1 4.4Å
18I98.5Very high95.7Very high5 Ų532.3 Ų32.33%0.02617%0.171CC..EExtended strand (participates in β ladder)trans-133138.2-178.9-47.8-173.3000107.9M6 S7 F20 E26 S28 Y434 E436 A439M6-I18 CarbonylContact C-O 3.5Å; M6-I18 WeakPolarHBondContact CA-O 3.5Å; S7-I18 PolarHBondContact N-O 3.27Å; S7-I18 PolarHBondContact O-N 2.87Å; S7-I18 WeakPolarHBondContact OG-CB 3.02Å; S7-I18 PolarHBondContact OG-O 2.77Å; I18-F20 HydrophobicContact CB-CE2 3.82Å; I18-F20 HydrophobicContact CB-CZ 3.99Å; I18-F20 HydrophobicContact CG2-CD2 4.27Å; I18-F20 HydrophobicContact CG2-CE1 3.95Å; I18-F20 HydrophobicContact CG2-CE2 3.65Å; I18-F20 HydrophobicContact CG2-CZ 3.45Å; I18-F20 VanDerWaalsContact CG2-CZ 3.45Å; I18-E26 HydrophobicContact CG2-CB 4.26Å; I18-E26 HydrophobicContact CG2-CG 3.72Å; I18-S28 WeakPolarHBondContact CA-O 3.49Å; I18-Y434 WeakPolarHBondContact CD1-OH 3.38Å; I18-E436 HydrophobicContact CD1-CB 4.2Å; I18-E436 HydrophobicContact CD1-CG 4.46Å; I18-A439 HydrophobicContact CD1-CB 3.64Å; I18-A439 HydrophobicContact CG1-CB 4.26Å
19V98.5Very high95.6Very high0 Ų034 Ų340%018%0.183CC..EExtended strand (participates in β ladder)trans-111.8128.7177.7-176.80000109.4Y4 I5 M6 V27 S28 L68 I73Y4-V19 HydrophobicContact CD1-CG1 4.21Å; Y4-V19 HydrophobicContact CG-CG1 3.83Å; I5-V19 CarbonylContact O-C 3.54Å; I5-V19 WeakPolarHBondContact O-CA 3.32Å; M6-V19 HydrophobicContact CB-CG2 4.48Å; M6-V19 HydrophobicContact CE-CG2 3.92Å; M6-V19 HydrophobicContact CG-CG2 4.43Å; V19-V27 PolarHBondContact O-N 2.93Å; V19-S28 PolarHBondContact N-O 3.11Å; V19-L68 HydrophobicContact CB-CD1 4.08Å; V19-L68 HydrophobicContact CG1-CD1 3.53Å; V19-L68 HydrophobicContact CG2-CD1 4.25Å; V19-I73 HydrophobicContact CG1-CD1 4.07Å; V19-I73 HydrophobicContact CG2-CD1 4.42Å
20F97.5Very high95.6Very high0 Ų034.1 Ų34.10%019%0.185CC..EExtended strand (participates in β ladder)trans-115.1142.8-176.7-63-83.3000112.2Y4 I5 S7 I18 K25 E26 Y434 A439 L440 A443Y4-F20 WeakPolarHBondContact CA-O 3.32Å; Y4-F20 WeakPolarHBondContact CB-O 3.47Å; I5-F20 PolarHBondContact N-O 3Å; I5-F20 PolarHBondContact O-N 3.29Å; S7-F20 WeakPolarHBondContact OG-CE2 3.2Å; I18-F20 HydrophobicContact CB-CE2 3.82Å; I18-F20 HydrophobicContact CB-CZ 3.99Å; I18-F20 HydrophobicContact CG2-CD2 4.27Å; I18-F20 HydrophobicContact CG2-CE1 3.95Å; I18-F20 HydrophobicContact CG2-CE2 3.65Å; I18-F20 HydrophobicContact CG2-CZ 3.45Å; I18-F20 VanDerWaalsContact CG2-CZ 3.45Å; F20-K25 VanDerWaalsContact CA-O 3.3Å; F20-K25 WeakPolarHBondContact CA-O 2.98Å; F20-E26 HydrophobicContact CE1-CB 4.33Å; F20-Y434 AromaticContact CE1-CE1 3.83Å; F20-Y434 HydrophobicContact CE1-CE1 3.83Å; F20-Y434 AromaticContact CE1-CZ 3.98Å; F20-Y434 AromaticContact CZ-CE1 3.96Å; F20-Y434 HydrophobicContact CZ-CE1 3.96Å; F20-A439 HydrophobicContact CE2-CB 4.45Å; F20-A439 HydrophobicContact CZ-CB 4.39Å; F20-L440 HydrophobicContact CD1-CD1 4.05Å; F20-L440 HydrophobicContact CE1-CD1 3.9Å; F20-L440 HydrophobicContact CZ-CB 4.32Å; F20-L440 HydrophobicContact CZ-CD1 4.28Å; F20-A443 HydrophobicContact CD2-CB 3.51Å; F20-A443 HydrophobicContact CE2-CB 3.87Å; F20-A443 HydrophobicContact CG-CB 4.26Å
21D95.9Very high95.6Very high44 Ų4438.8 Ų38.824%0.23521%0.208CC..  trans-86.3-179.9171.673.412.5000113Y4 A23 G24 K25 V27 Y452Y4-D21 HydrophobicContact CD1-CB 4.24Å; Y4-D21 HydrophobicContact CE1-CB 4.27Å; D21-A23 PolarHBondContact O-N 2.73Å; D21-A23 VanDerWaalsContact OD1-CA 3.3Å; D21-A23 WeakPolarHBondContact OD1-CA 2.9Å; D21-A23 WeakPolarHBondContact OD1-CB 3.3Å; D21-A23 PolarHBondContact OD1-N 3.3Å; D21-G24 PolarHBondContact O-N 2.82Å; D21-G24 PolarHBondContact OD1-N 3.01Å; D21-G24 VanDerWaalsContact OD1-N 3.12Å; D21-K25 PolarHBondContact N-O 3.46Å; D21-K25 PolarHBondContact OD1-N 2.96Å; D21-V27 HydrophobicContact CB-CG2 3.8Å; D21-Y452 WeakPolarHBondContact CA-OH 3.47Å
22K93.9Very high95.7Very high118 Ų11842.8 Ų42.851%0.51322%0.221SC..THydrogen-bonded Turntrans-64.4-19.6-179.9-72.6-164.1176.6-158.20113.7G24 Y452 W453 F462K22-G24 VanDerWaalsContact C-N 3.31Å; K22-Y452 HydrophobicContact CB-CE1 4.28Å; K22-Y452 HydrophobicContact CD-CE2 4.38Å; K22-Y452 HydrophobicContact CG-CE1 3.73Å; K22-Y452 HydrophobicContact CG-CE2 3.74Å; K22-Y452 WeakPolarHBondContact CG-OH 3.47Å; K22-Y452 PolarHBondContact N-OH 3.04Å; K22-W453 PolarHBondContact O-NE1 2.74Å; K22-F462 WeakPolarHBondContact O-CZ 3.27Å
23A91.1Very high95.8Very high46 Ų4649.3 Ų49.338%0.3825%0.25SS..THydrogen-bonded Turntrans-90.65.5176.500000112.5D21 K25D21-A23 PolarHBondContact O-N 2.73Å; D21-A23 VanDerWaalsContact OD1-CA 3.3Å; D21-A23 WeakPolarHBondContact OD1-CA 2.9Å; D21-A23 WeakPolarHBondContact OD1-CB 3.3Å; D21-A23 PolarHBondContact OD1-N 3.3Å; A23-K25 VanDerWaalsContact C-N 3.28Å; A23-K25 HydrophobicContact CB-CD 4.46Å; A23-K25 HydrophobicContact CB-CG 4.3Å; A23-K25 PolarHBondContact O-N 3.26Å
24G89.7Confident96.2Very high14 Ų1447.7 Ų47.714%0.14424%0.239CC..SBendtrans72.419.4-178.100000113.4D21 K22D21-G24 PolarHBondContact O-N 2.82Å; D21-G24 PolarHBondContact OD1-N 3.01Å; D21-G24 VanDerWaalsContact OD1-N 3.12Å; K22-G24 VanDerWaalsContact C-N 3.31Å
25K93.2Very high96.2Very high135 Ų13550.4 Ų50.459%0.58726%0.256SS*.  trans-93.1140.7179.7-62.9-179178.1179.40111F20 D21 A23 V27F20-K25 VanDerWaalsContact CA-O 3.3Å; F20-K25 WeakPolarHBondContact CA-O 2.98Å; D21-K25 PolarHBondContact N-O 3.46Å; D21-K25 PolarHBondContact OD1-N 2.96Å; A23-K25 VanDerWaalsContact C-N 3.28Å; A23-K25 HydrophobicContact CB-CD 4.46Å; A23-K25 HydrophobicContact CB-CG 4.3Å; A23-K25 PolarHBondContact O-N 3.26Å; K25-V27 PolarHBondContact O-N 2.54Å
26E95.8Very high96Very high82 Ų8252.6 Ų52.638%0.38327%0.266SS..EExtended strand (participates in β ladder)trans-63.3120.4170.2176.7176.1157.800110.2I18 F20 S29 Y434I18-E26 HydrophobicContact CG2-CB 4.26Å; I18-E26 HydrophobicContact CG2-CG 3.72Å; F20-E26 HydrophobicContact CE1-CB 4.33Å; E26-S29 WeakPolarHBondContact OE1-CB 3.18Å; E26-S29 PolarHBondContact OE1-OG 2.66Å; E26-Y434 HydrophobicContact CB-CE2 4.27Å; E26-Y434 VanDerWaalsContact OE2-CE2 3.3Å; E26-Y434 WeakPolarHBondContact OE2-CE2 2.96Å; E26-Y434 PolarHBondContact OE2-OH 2.97Å
27V97.3Very high95.8Very high55 Ų5552.2 Ų52.233%0.33327%0.267SS..EExtended strand (participates in β ladder)trans-92.1-41.4174.8177.60000110.2Y4 V19 D21 K25 L68Y4-V27 HydrophobicContact CD1-CG2 3.87Å; Y4-V27 HydrophobicContact CE1-CB 4.49Å; Y4-V27 HydrophobicContact CE1-CG1 4.23Å; Y4-V27 HydrophobicContact CE1-CG2 3.75Å; V19-V27 PolarHBondContact O-N 2.93Å; D21-V27 HydrophobicContact CB-CG2 3.8Å; K25-V27 PolarHBondContact O-N 2.54Å; V27-L68 HydrophobicContact CG1-CD1 4.28Å; V27-L68 HydrophobicContact CG1-CD2 4.48Å
28S97.9Very high95.6Very high7 Ų758.7 Ų58.75%0.04930%0.295CS..EExtended strand (participates in β ladder)trans-158.1158.2176.259.90000110.7I18 V19 S62I18-S28 WeakPolarHBondContact CA-O 3.49Å; V19-S28 PolarHBondContact N-O 3.11Å; S28-S62 VanDerWaalsContact CB-O 3.28Å; S28-S62 WeakPolarHBondContact CB-O 3.4Å; S28-S62 PolarHBondContact OG-O 2.86Å
29S97.7Very high95.4Very high36 Ų3661.9 Ų61.925%0.25232%0.316SS..EExtended strand (participates in β ladder)trans-144.1167.5173.857.20000110.9A17 E26A17-S29 CarbonylContact O-C 3.55Å; A17-S29 WeakPolarHBondContact O-CA 3.41Å; E26-S29 WeakPolarHBondContact OE1-CB 3.18Å; E26-S29 PolarHBondContact OE1-OG 2.66Å
30S98.3Very high95.1Very high22 Ų2267.6 Ų67.615%0.15434%0.341CS..EExtended strand (participates in β ladder)trans-152.7145.3167.9-168.20000109.1R16 A17 V58R16-S30 CarbonylContact C-O 3.58Å; R16-S30 WeakPolarHBondContact CA-O 3.44Å; A17-S30 PolarHBondContact N-O 3.31Å; A17-S30 PolarHBondContact O-N 3.35Å; S30-V58 WeakPolarHBondContact CB-O 3.39Å
31Q97.6Very high94.4Very high99 Ų9973.9 Ų73.946%0.46338%0.382SS..EExtended strand (participates in β ladder)trans-133.5140.3-178.6-177.8175.47.300110.4S14 S15 R16S14-Q31 PolarHBondContact OG-NE2 3.41Å; S15-Q31 WeakPolarHBondContact O-CA 3.35Å; R16-Q31 HydrophobicContact CG-CB 3.87Å; R16-Q31 HydrophobicContact CG-CG 3.66Å; R16-Q31 VanDerWaalsContact NE-NE2 3.15Å; R16-Q31 VanDerWaalsContact NH2-NE2 3.11Å
32K97.3Very high93.9Very high97 Ų9773.8 Ų73.842%0.42239%0.391SS..EExtended strand (participates in β ladder)trans-144.5126.1174.8-172171.8174.6177.90111.4S14 S15 S57 V58S14-K32 CarbonylContact C-O 3.46Å; S14-K32 VanDerWaalsContact CA-O 3.23Å; S14-K32 WeakPolarHBondContact CA-O 3.32Å; S14-K32 WeakPolarHBondContact CB-O 3.25Å; S15-K32 PolarHBondContact N-O 3.08Å; S15-K32 PolarHBondContact O-N 3.31Å; K32-S57 VanDerWaalsContact CD-CB 3.5Å; K32-S57 PolarHBondContact NZ-OG 2.92Å; K32-V58 HydrophobicContact CB-CG1 3.65Å
33E94.6Very high93.9Very high150 Ų15070.4 Ų70.470%0.70138%0.375SS*.EExtended strand (participates in β ladder)trans-71.1157.3171.5-65.9-176.8165.200111.5T13T13-E33 WeakPolarHBondContact O-CA 3.49Å
34F96.2Very high94.1Very high13 Ų1368.6 Ų68.66%0.05736%0.36CS..  trans-139.1159.817358.5-97.1000110.4G11 T12 T13 Q36 H46 E50 I51G11-F34 WeakPolarHBondContact O-CE1 3.39Å; G11-F34 WeakPolarHBondContact O-CZ 3.32Å; T12-F34 VanDerWaalsContact O-CE2 3.28Å; T12-F34 WeakPolarHBondContact O-CE2 3.36Å; T12-F34 WeakPolarHBondContact O-CZ 3.3Å; T13-F34 PolarHBondContact O-N 2.9Å; F34-Q36 PolarHBondContact O-NE2 2.99Å; F34-H46 HydrophobicContact CE2-CB 4.46Å; F34-H46 AromaticContact CE2-CD2 3.74Å; F34-H46 AromaticContact CE2-CE1 3.6Å; F34-H46 AromaticContact CE2-CG 3.72Å; F34-H46 AromaticContact CE2-ND1 3.61Å; F34-H46 AromaticContact CE2-NE2 3.69Å; F34-E50 WeakPolarHBondContact CA-OE1 3.41Å; F34-E50 HydrophobicContact CB-CG 4.03Å; F34-I51 HydrophobicContact CD2-CG1 4.29Å; F34-I51 HydrophobicContact CE2-CG1 4.1Å; F34-I51 HydrophobicContact CZ-CG1 4.25Å
35T95.5Very high94.5Very high67 Ų6768.2 Ų68.241%0.41135%0.354SS..  trans-64.5138.5-169.9-50.50000112E50T35-E50 WeakPolarHBondContact CB-OE1 3.39Å; T35-E50 VanDerWaalsContact CB-OE2 3.24Å; T35-E50 WeakPolarHBondContact CB-OE2 3.48Å; T35-E50 PolarHBondContact N-OE1 3.27Å; T35-E50 PolarHBondContact OG1-OE1 3.05Å; T35-E50 PolarHBondContact OG1-OE2 3.01Å
36Q92.7Very high94.8Very high46 Ų4661.8 Ų61.822%0.21533%0.326CS..  trans-104.2117.3174-51.6-67-72.300107.9T12 F34 F38 H46T12-Q36 PolarHBondContact O-NE2 3.16Å; T12-Q36 VanDerWaalsContact O-NE2 3.09Å; T12-Q36 PolarHBondContact O-OE1 3.29Å; F34-Q36 PolarHBondContact O-NE2 2.99Å; Q36-F38 HydrophobicContact CB-CE2 3.79Å; Q36-F38 HydrophobicContact CB-CZ 3.65Å; Q36-H46 PolarHBondContact NE2-NE2 2.88Å; Q36-H46 VanDerWaalsContact NE2-NE2 3.2Å; Q36-H46 PolarHBondContact OE1-NE2 3.03Å
37H95Very high94.9Very high61 Ų6160.5 Ų60.528%0.28232%0.322SS..BIsolated β-bridgetrans-97.7133-179.9-59-87.9000110.8V44 E45H37-V44 WeakPolarHBondContact O-CA 3.36Å; H37-E45 HydrophobicContact CB-CB 4.07Å; H37-E45 WeakPolarHBondContact CB-O 3.28Å; H37-E45 PolarHBondContact N-O 3.44Å; H37-E45 PolarHBondContact O-N 2.96Å
38F92.9Very high95Very high135 Ų13558 Ų5859%0.59231%0.307SS*.  trans-124.871.4177.1-51.5-73.4000110.9Q36 K40 W43 V44Q36-F38 HydrophobicContact CB-CE2 3.79Å; Q36-F38 HydrophobicContact CB-CZ 3.65Å; F38-K40 VanDerWaalsContact C-N 3.25Å; F38-K40 PolarHBondContact O-N 3.19Å; F38-W43 WeakPolarHBondContact CA-O 3.37Å; F38-V44 HydrophobicContact CD1-CG1 4.49Å; F38-V44 HydrophobicContact CD1-CG2 4.13Å; F38-V44 HydrophobicContact CE1-CG1 4.08Å; F38-V44 HydrophobicContact CE1-CG2 4.1Å
39P94.8Very high95Very high72 Ų7260.1 Ų60.147%0.46832%0.317SS..SBendtrans-60-33.9-172.5-24.334.7000114W43 E45P39-W43 HydrophobicContact CB-CE3 4.44Å; P39-E45 HydrophobicContact CG-CG 4.39Å
40K91.7Very high95.1Very high120 Ų12060.9 Ų60.952%0.52232%0.317SS..SBendtrans-138157.5173-65-177-176.8177.20109.4F38 G42 W43F38-K40 VanDerWaalsContact C-N 3.25Å; F38-K40 PolarHBondContact O-N 3.19Å; K40-G42 PolarHBondContact O-N 3.12Å; K40-W43 HydrophobicContact CB-CB 4.31Å; K40-W43 HydrophobicContact CB-CD2 4.04Å; K40-W43 HydrophobicContact CB-CG 3.83Å; K40-W43 HydrophobicContact CD-CD2 4.23Å; K40-W43 HydrophobicContact CD-CH2 4.23Å; K40-W43 HydrophobicContact CD-CZ2 3.87Å; K40-W43 HydrophobicContact CG-CD2 4.35Å; K40-W43 WeakPolarHBondContact O-CB 3.23Å; K40-W43 PolarHBondContact O-N 2.97Å
41P84.5Confident95.1Very high133 Ų13359.8 Ų59.886%0.86431%0.31SS*.THydrogen-bonded Turntrans-52127.5171.3-26.835.8000111.8W43P41-W43 VanDerWaalsContact C-N 3.28Å; P41-W43 PolarHBondContact O-N 2.72Å
42G85.3Confident95.1Very high41 Ų4155.8 Ų55.842%0.42329%0.29SS..THydrogen-bonded Turntrans83.3-9.6-176.800000115.2K40 K105K40-G42 PolarHBondContact O-N 3.12Å; G42-K105 PolarHBondContact O-N 3.3Å
43W93.8Very high95.2Very high47 Ų4755.1 Ų55.118%0.17829%0.291CS..  trans-89.3135.7173.9-67.530.5000109.4F38 P39 K40 P41 Q106 W142F38-W43 WeakPolarHBondContact CA-O 3.37Å; P39-W43 HydrophobicContact CB-CE3 4.44Å; K40-W43 HydrophobicContact CB-CB 4.31Å; K40-W43 HydrophobicContact CB-CD2 4.04Å; K40-W43 HydrophobicContact CB-CG 3.83Å; K40-W43 HydrophobicContact CD-CD2 4.23Å; K40-W43 HydrophobicContact CD-CH2 4.23Å; K40-W43 HydrophobicContact CD-CZ2 3.87Å; K40-W43 HydrophobicContact CG-CD2 4.35Å; K40-W43 WeakPolarHBondContact O-CB 3.23Å; K40-W43 PolarHBondContact O-N 2.97Å; P41-W43 VanDerWaalsContact C-N 3.28Å; P41-W43 PolarHBondContact O-N 2.72Å; W43-Q106 HydrophobicContact CD2-CB 3.53Å; W43-Q106 HydrophobicContact CE3-CB 4.12Å; W43-Q106 HydrophobicContact CG-CB 3.75Å; W43-Q106 HydrophobicContact CZ2-CB 3.93Å; W43-W142 HydrophobicContact CH2-CH2 4.14Å; W43-W142 AromaticContact CH2-CZ2 3.49Å; W43-W142 HydrophobicContact CH2-CZ2 3.49Å; W43-W142 VanDerWaalsContact CH2-CZ2 3.49Å; W43-W142 HydrophobicContact CZ2-CZ2 4.36Å; W43-W142 HydrophobicContact CZ3-CH2 4Å; W43-W142 AromaticContact CZ3-CZ2 3.81Å; W43-W142 HydrophobicContact CZ3-CZ2 3.81Å
44V94.4Very high95.4Very high9 Ų948.1 Ų48.16%0.05526%0.259CS..  trans-135.1120.2178.5-169.80000108.7H37 F38 V101 Q103 S104H37-V44 WeakPolarHBondContact O-CA 3.36Å; F38-V44 HydrophobicContact CD1-CG1 4.49Å; F38-V44 HydrophobicContact CD1-CG2 4.13Å; F38-V44 HydrophobicContact CE1-CG1 4.08Å; F38-V44 HydrophobicContact CE1-CG2 4.1Å; V44-V101 HydrophobicContact CB-CB 4.05Å; V44-V101 HydrophobicContact CB-CG2 4.5Å; V44-V101 HydrophobicContact CG1-CB 3.82Å; V44-V101 HydrophobicContact CG1-CG1 4.1Å; V44-V101 HydrophobicContact CG1-CG2 3.97Å; V44-V101 WeakPolarHBondContact O-CB 3.35Å; V44-V101 WeakPolarHBondContact O-CG2 3.37Å; V44-V101 PolarHBondContact O-N 2.86Å; V44-Q103 HydrophobicContact CB-CB 4.11Å; V44-Q103 HydrophobicContact CG1-CB 4.35Å; V44-Q103 HydrophobicContact CG2-CB 3.81Å; V44-S104 PolarHBondContact N-OG 3.34Å; V44-S104 WeakPolarHBondContact O-CB 3.29Å
45E98.5Very high95.5Very high5 Ų547.5 Ų47.52%0.02326%0.256CS..EExtended strand (participates in β ladder)trans-131.9150.5-175.4-75.4176.2-156.200111.3H37 P39 Y97 N98 A99H37-E45 HydrophobicContact CB-CB 4.07Å; H37-E45 WeakPolarHBondContact CB-O 3.28Å; H37-E45 PolarHBondContact N-O 3.44Å; H37-E45 PolarHBondContact O-N 2.96Å; P39-E45 HydrophobicContact CG-CG 4.39Å; E45-Y97 PolarHBondContact OE1-OH 2.97Å; E45-N98 HydrophobicContact CB-CB 3.96Å; E45-N98 HydrophobicContact CG-CB 4.21Å; E45-N98 WeakPolarHBondContact OE2-CB 3.05Å; E45-N98 PolarHBondContact OE2-ND2 3.41Å; E45-A99 VanDerWaalsContact CA-O 3.3Å; E45-A99 WeakPolarHBondContact CA-O 3.31Å
46H98.6Very high95.6Very high0 Ų047.7 Ų47.70%025%0.252CS..EExtended strand (participates in β ladder)trans-125.5146.1170.9-62.8153000110.9T12 F34 Q36 A48 I51 Q81 N98 A99 V101T12-H46 PolarHBondContact O-CE1 2.85Å; T12-H46 PolarHBondContact O-NE2 2.97Å; F34-H46 HydrophobicContact CE2-CB 4.46Å; F34-H46 AromaticContact CE2-CD2 3.74Å; F34-H46 AromaticContact CE2-CE1 3.6Å; F34-H46 AromaticContact CE2-CG 3.72Å; F34-H46 AromaticContact CE2-ND1 3.61Å; F34-H46 AromaticContact CE2-NE2 3.69Å; Q36-H46 PolarHBondContact NE2-NE2 2.88Å; Q36-H46 VanDerWaalsContact NE2-NE2 3.2Å; Q36-H46 PolarHBondContact OE1-NE2 3.03Å; H46-A48 PolarHBondContact O-N 3.29Å; H46-I51 HydrophobicContact CB-CD1 3.58Å; H46-I51 HydrophobicContact CB-CG1 4.32Å; H46-Q81 PolarHBondContact ND1-NE2 2.66Å; H46-N98 CarbonylContact O-C 3.59Å; H46-A99 HydrophobicContact CB-CB 4.35Å; H46-A99 PolarHBondContact N-O 3.45Å; H46-A99 WeakPolarHBondContact O-CB 3.2Å; H46-A99 PolarHBondContact O-N 2.94Å; H46-V101 HydrophobicContact CB-CG2 4.24Å; H46-V101 WeakPolarHBondContact CE1-CG2 3.32Å; H46-V101 VanDerWaalsContact CG-CG2 3.5Å; H46-V101 VanDerWaalsContact ND1-CG2 3.31Å; H46-V101 WeakPolarHBondContact ND1-CG2 3.39Å
47D98.7Very high95.9Very high56 Ų5647.4 Ų47.430%0.29926%0.256SS..  trans-76.3116.1164.6-177.9-20.1000109.3N49 E50 I51D47-N49 VanDerWaalsContact C-N 3.25Å; D47-N49 PolarHBondContact O-N 2.96Å; D47-N49 WeakPolarHBondContact OD1-CA 3.32Å; D47-N49 WeakPolarHBondContact OD1-CB 3.44Å; D47-N49 PolarHBondContact OD1-N 3.03Å; D47-E50 HydrophobicContact CB-CB 3.81Å; D47-E50 WeakPolarHBondContact O-CB 3.3Å; D47-E50 PolarHBondContact O-N 3.18Å; D47-E50 VanDerWaalsContact O-N 3.11Å; D47-E50 PolarHBondContact OD1-N 3.45Å; D47-I51 PolarHBondContact O-N 2.87Å
48A98.7Very high96.1Very high1 Ų144.5 Ų44.51%0.00824%0.242CC..Hα-helixtrans-65.3-26.2-179.300000113.3H46 W52 V86 P95 W167H46-A48 PolarHBondContact O-N 3.29Å; A48-W52 PolarHBondContact O-N 3.1Å; A48-V86 HydrophobicContact CB-CG1 3.75Å; A48-V86 HydrophobicContact CB-CG2 4.29Å; A48-P95 HydrophobicContact CB-CB 4.42Å; A48-P95 HydrophobicContact CB-CG 3.78Å; A48-W167 HydrophobicContact CB-CZ2 4.05Å; A48-W167 PolarHBondContact O-NE1 3.47Å
49N98.6Very high96.4Very high52 Ų5238.3 Ų38.328%0.27822%0.215SC..Hα-helixtrans-75-36172-66.9-53.7000111.4D47 W52 N53D47-N49 VanDerWaalsContact C-N 3.25Å; D47-N49 PolarHBondContact O-N 2.96Å; D47-N49 WeakPolarHBondContact OD1-CA 3.32Å; D47-N49 WeakPolarHBondContact OD1-CB 3.44Å; D47-N49 PolarHBondContact OD1-N 3.03Å; N49-W52 PolarHBondContact O-N 3.07Å; N49-N53 WeakPolarHBondContact O-CB 3.39Å; N49-N53 PolarHBondContact O-N 2.89Å; N49-N53 PolarHBondContact O-ND2 2.83Å
50E98.5Very high96.5Very high52 Ų5236.2 Ų36.224%0.24320%0.204CC..Hα-helixtrans-64.8-42.7172.8-169-176.8173.400111.2F34 T35 D47 W52 N53 S54F34-E50 WeakPolarHBondContact CA-OE1 3.41Å; F34-E50 HydrophobicContact CB-CG 4.03Å; T35-E50 WeakPolarHBondContact CB-OE1 3.39Å; T35-E50 VanDerWaalsContact CB-OE2 3.24Å; T35-E50 WeakPolarHBondContact CB-OE2 3.48Å; T35-E50 PolarHBondContact N-OE1 3.27Å; T35-E50 PolarHBondContact OG1-OE1 3.05Å; T35-E50 PolarHBondContact OG1-OE2 3.01Å; D47-E50 HydrophobicContact CB-CB 3.81Å; D47-E50 WeakPolarHBondContact O-CB 3.3Å; D47-E50 PolarHBondContact O-N 3.18Å; D47-E50 VanDerWaalsContact O-N 3.11Å; D47-E50 PolarHBondContact OD1-N 3.45Å; E50-W52 VanDerWaalsContact C-N 3.33Å; E50-W52 PolarHBondContact O-N 2.93Å; E50-N53 PolarHBondContact O-N 3.24Å; E50-S54 WeakPolarHBondContact O-CB 3.34Å; E50-S54 PolarHBondContact O-N 2.93Å
51I98.8Very high96.8Very high0 Ų031.1 Ų31.10%019%0.186CC..Hα-helixtrans-51.5-53.4169.1-77.1165.3000109.9Q10 F34 H46 D47 N53 S54 V55 I164 L168Q10-I51 HydrophobicContact CG-CG2 3.8Å; F34-I51 HydrophobicContact CD2-CG1 4.29Å; F34-I51 HydrophobicContact CE2-CG1 4.1Å; F34-I51 HydrophobicContact CZ-CG1 4.25Å; H46-I51 HydrophobicContact CB-CD1 3.58Å; H46-I51 HydrophobicContact CB-CG1 4.32Å; D47-I51 PolarHBondContact O-N 2.87Å; I51-N53 PolarHBondContact O-N 3Å; I51-S54 PolarHBondContact O-N 3.38Å; I51-S54 VanDerWaalsContact O-N 3.16Å; I51-S54 PolarHBondContact O-OG 3.11Å; I51-V55 PolarHBondContact O-N 3.2Å; I51-I164 HydrophobicContact CD1-CD1 4.06Å; I51-L168 HydrophobicContact CG2-CD2 4.37Å
52W98.7Very high97.5Very high14 Ų1424.8 Ų24.85%0.05315%0.145CC..Hα-helixtrans-60.5-43.1-179.9172.6-123000112.7A48 N49 E50 S54 V55 Q56 L168 K171 L172 H230A48-W52 PolarHBondContact O-N 3.1Å; N49-W52 PolarHBondContact O-N 3.07Å; E50-W52 VanDerWaalsContact C-N 3.33Å; E50-W52 PolarHBondContact O-N 2.93Å; W52-S54 VanDerWaalsContact C-N 3.31Å; W52-S54 PolarHBondContact O-N 3.49Å; W52-V55 HydrophobicContact CE3-CB 4.29Å; W52-V55 HydrophobicContact CE3-CG1 4.31Å; W52-V55 HydrophobicContact CZ3-CG1 4.07Å; W52-V55 PolarHBondContact O-N 3.35Å; W52-Q56 HydrophobicContact CD2-CG 4.02Å; W52-Q56 VanDerWaalsContact CE2-CD 3.42Å; W52-Q56 HydrophobicContact CE3-CG 4.3Å; W52-Q56 HydrophobicContact CH2-CG 3.77Å; W52-Q56 HydrophobicContact CZ2-CG 3.45Å; W52-Q56 VanDerWaalsContact CZ2-CG 3.45Å; W52-Q56 HydrophobicContact CZ3-CG 4.18Å; W52-Q56 WeakPolarHBondContact O-CG 3.43Å; W52-Q56 PolarHBondContact O-N 3.16Å; W52-L168 HydrophobicContact CE3-CD2 4.19Å; W52-K171 HydrophobicContact CD2-CB 3.7Å; W52-K171 HydrophobicContact CD2-CG 3.94Å; W52-K171 HydrophobicContact CE3-CB 3.7Å; W52-K171 HydrophobicContact CE3-CG 4.18Å; W52-K171 HydrophobicContact CG-CB 4.37Å; W52-K171 HydrophobicContact CG-CG 4.09Å; W52-K171 HydrophobicContact CH2-CB 4.03Å; W52-K171 HydrophobicContact CZ2-CB 4.02Å; W52-K171 HydrophobicContact CZ3-CB 3.87Å; W52-L172 HydrophobicContact CH2-CD2 3.85Å; W52-L172 HydrophobicContact CH2-CG 4.13Å; W52-L172 HydrophobicContact CZ3-CD2 4.08Å; W52-L172 HydrophobicContact CZ3-CG 4.04Å; W52-H230 AromaticContact CZ2-ND1 3.94Å
53N98.4Very high98.1Very high83 Ų8323.4 Ų23.444%0.44413%0.127SC..Hα-helixtrans-63.5-36.7176.7-69.6-23000112.2N49 E50 I51 Q56 S57N49-N53 WeakPolarHBondContact O-CB 3.39Å; N49-N53 PolarHBondContact O-N 2.89Å; N49-N53 PolarHBondContact O-ND2 2.83Å; E50-N53 PolarHBondContact O-N 3.24Å; I51-N53 PolarHBondContact O-N 3Å; N53-Q56 PolarHBondContact OD1-NE2 3.41Å; N53-S57 WeakPolarHBondContact O-CB 3.16Å; N53-S57 PolarHBondContact O-N 2.79Å; N53-S57 PolarHBondContact O-OG 2.99Å
54S98.6Very high98.3Very high3 Ų327.6 Ų27.62%0.02115%0.152CC..Hα-helixtrans-65.8-41.3175.277.70000111.4S15 E50 I51 W52 S57 V58S15-S54 WeakPolarHBondContact CB-OG 3.41Å; S15-S54 PolarHBondContact OG-OG 3.31Å; E50-S54 WeakPolarHBondContact O-CB 3.34Å; E50-S54 PolarHBondContact O-N 2.93Å; I51-S54 PolarHBondContact O-N 3.38Å; I51-S54 VanDerWaalsContact O-N 3.16Å; I51-S54 PolarHBondContact O-OG 3.11Å; W52-S54 VanDerWaalsContact C-N 3.31Å; W52-S54 PolarHBondContact O-N 3.49Å; S54-S57 WeakPolarHBondContact O-CB 3.29Å; S54-S57 PolarHBondContact O-N 3.32Å; S54-V58 WeakPolarHBondContact O-CG2 3.38Å; S54-V58 PolarHBondContact O-N 3.4Å; S54-V58 VanDerWaalsContact O-N 3.07Å
55V98.7Very high98.4Very high0 Ų033.5 Ų33.50%018%0.179CC..Hα-helixtrans-62.4-49.1175.4170.70000111.4I8 Q10 I51 W52 S57 V58 I59 L168I8-V55 HydrophobicContact CD1-CG1 4.34Å; I8-V55 HydrophobicContact CG2-CG1 3.83Å; I8-V55 HydrophobicContact CG2-CG2 4.26Å; Q10-V55 HydrophobicContact CG-CG2 4.17Å; I51-V55 PolarHBondContact O-N 3.2Å; W52-V55 HydrophobicContact CE3-CB 4.29Å; W52-V55 HydrophobicContact CE3-CG1 4.31Å; W52-V55 HydrophobicContact CZ3-CG1 4.07Å; W52-V55 PolarHBondContact O-N 3.35Å; V55-S57 PolarHBondContact O-N 3.06Å; V55-V58 VanDerWaalsContact O-CG2 3.23Å; V55-V58 WeakPolarHBondContact O-CG2 3.32Å; V55-V58 PolarHBondContact O-N 2.89Å; V55-I59 HydrophobicContact CG1-CD1 3.81Å; V55-I59 HydrophobicContact CG1-CG1 4.37Å; V55-I59 WeakPolarHBondContact O-CG1 3.35Å; V55-I59 PolarHBondContact O-N 3.29Å; V55-L168 HydrophobicContact CB-CD2 4.39Å; V55-L168 HydrophobicContact CG1-CD2 4.46Å; V55-L168 HydrophobicContact CG2-CD1 4.3Å; V55-L168 HydrophobicContact CG2-CD2 3.86Å
56Q98.5Very high98.3Very high71 Ų7134.4 Ų34.433%0.33219%0.189SC..Hα-helixtrans-56.6-39.9175-70.5-179.799.600112W52 N53 A60W52-Q56 HydrophobicContact CD2-CG 4.02Å; W52-Q56 VanDerWaalsContact CE2-CD 3.42Å; W52-Q56 HydrophobicContact CE3-CG 4.3Å; W52-Q56 HydrophobicContact CH2-CG 3.77Å; W52-Q56 HydrophobicContact CZ2-CG 3.45Å; W52-Q56 VanDerWaalsContact CZ2-CG 3.45Å; W52-Q56 HydrophobicContact CZ3-CG 4.18Å; W52-Q56 WeakPolarHBondContact O-CG 3.43Å; W52-Q56 PolarHBondContact O-N 3.16Å; N53-Q56 PolarHBondContact OD1-NE2 3.41Å; Q56-A60 WeakPolarHBondContact O-CB 3.41Å; Q56-A60 PolarHBondContact O-N 3.31Å; Q56-A60 VanDerWaalsContact O-N 3.13Å
57S98.4Very high98.2Very high41 Ų4137.5 Ų37.529%0.28722%0.222SC..Hα-helixtrans-63.8-44.1179.5-57.10000112K32 N53 S54 V55 G61K32-S57 VanDerWaalsContact CD-CB 3.5Å; K32-S57 PolarHBondContact NZ-OG 2.92Å; N53-S57 WeakPolarHBondContact O-CB 3.16Å; N53-S57 PolarHBondContact O-N 2.79Å; N53-S57 PolarHBondContact O-OG 2.99Å; S54-S57 WeakPolarHBondContact O-CB 3.29Å; S54-S57 PolarHBondContact O-N 3.32Å; V55-S57 PolarHBondContact O-N 3.06Å; S57-G61 PolarHBondContact O-N 3.4Å
58V98.7Very high98.1Very high0 Ų035.8 Ų35.80%021%0.212CC..Hα-helixtrans-77-32.7-177.7-63.50000112.7A17 S30 K32 S54 V55 G61 S62A17-V58 HydrophobicContact CB-CB 4.04Å; A17-V58 HydrophobicContact CB-CG2 3.88Å; A17-V58 WeakPolarHBondContact CB-O 3.5Å; S30-V58 WeakPolarHBondContact CB-O 3.39Å; K32-V58 HydrophobicContact CB-CG1 3.65Å; S54-V58 WeakPolarHBondContact O-CG2 3.38Å; S54-V58 PolarHBondContact O-N 3.4Å; S54-V58 VanDerWaalsContact O-N 3.07Å; V55-V58 VanDerWaalsContact O-CG2 3.23Å; V55-V58 WeakPolarHBondContact O-CG2 3.32Å; V55-V58 PolarHBondContact O-N 2.89Å; V58-G61 PolarHBondContact O-N 3Å; V58-S62 WeakPolarHBondContact O-CB 3.39Å; V58-S62 PolarHBondContact O-N 2.92Å; V58-S62 PolarHBondContact O-OG 3.21Å
59I98.5Very high98Very high5 Ų541.4 Ų41.43%0.02624%0.237CC..Hα-helixtrans-56.9-52.8169.4-68.9170.1000109.1M6 I8 A17 V55 G61 S62 L63 L172 F231 Y232M6-I59 HydrophobicContact CE-CG2 4.23Å; M6-I59 HydrophobicContact SD-CG1 4.14Å; M6-I59 HydrophobicContact SD-CG2 4.04Å; I8-I59 HydrophobicContact CD1-CD1 3.67Å; I8-I59 HydrophobicContact CD1-CG1 4.09Å; I8-I59 HydrophobicContact CG1-CD1 4.36Å; I8-I59 HydrophobicContact CG1-CG1 4.23Å; A17-I59 HydrophobicContact CB-CG1 4.4Å; V55-I59 HydrophobicContact CG1-CD1 3.81Å; V55-I59 HydrophobicContact CG1-CG1 4.37Å; V55-I59 WeakPolarHBondContact O-CG1 3.35Å; V55-I59 PolarHBondContact O-N 3.29Å; I59-G61 PolarHBondContact O-N 3.48Å; I59-S62 PolarHBondContact O-N 3.25Å; I59-S62 PolarHBondContact O-OG 2.97Å; I59-L63 HydrophobicContact CG2-CD1 4.35Å; I59-L63 WeakPolarHBondContact O-CG 3.27Å; I59-L63 PolarHBondContact O-N 3.32Å; I59-L172 HydrophobicContact CD1-CD2 4.37Å; I59-F231 HydrophobicContact CG2-CD2 4.39Å; I59-F231 HydrophobicContact CG2-CE2 3.79Å; I59-Y232 HydrophobicContact CG2-CE2 4.06Å
60A98.2Very high97.9Very high28 Ų2840.3 Ų40.323%0.23123%0.232CC..Hα-helixtrans-58.2-46.9177.400000112Q56 S62 L63 I64 Y232Q56-A60 WeakPolarHBondContact O-CB 3.41Å; Q56-A60 PolarHBondContact O-N 3.31Å; Q56-A60 VanDerWaalsContact O-N 3.13Å; A60-S62 PolarHBondContact O-N 2.95Å; A60-L63 PolarHBondContact O-N 3.18Å; A60-I64 WeakPolarHBondContact O-CD1 3.05Å; A60-I64 VanDerWaalsContact O-CG1 3.23Å; A60-I64 WeakPolarHBondContact O-CG1 3.47Å; A60-I64 PolarHBondContact O-N 2.8Å; A60-Y232 VanDerWaalsContact CA-OH 3.23Å; A60-Y232 WeakPolarHBondContact CA-OH 3.43Å; A60-Y232 VanDerWaalsContact CB-OH 3.24Å; A60-Y232 WeakPolarHBondContact CB-OH 3.46Å; A60-Y232 PolarHBondContact N-OH 2.84Å
61G98.3Very high97.8Very high13 Ų1342 Ų4213%0.13424%0.243CC..Hα-helixtrans-58.3-47.4179.300000112.6S57 V58 I59 L63 I64 E65S57-G61 PolarHBondContact O-N 3.4Å; V58-G61 PolarHBondContact O-N 3Å; I59-G61 PolarHBondContact O-N 3.48Å; G61-L63 VanDerWaalsContact C-N 3.34Å; G61-L63 PolarHBondContact O-N 3.29Å; G61-I64 PolarHBondContact O-N 3.46Å; G61-E65 WeakPolarHBondContact O-CB 3.48Å; G61-E65 WeakPolarHBondContact O-CG 3.37Å; G61-E65 PolarHBondContact O-N 3.27Å
62S98.2Very high97.7Very high0 Ų043.2 Ų43.20%025%0.249CC..Hα-helixtrans-63.8-37.7-178.767.60000112.7S28 V58 I59 A60 G66S28-S62 VanDerWaalsContact CB-O 3.28Å; S28-S62 WeakPolarHBondContact CB-O 3.4Å; S28-S62 PolarHBondContact OG-O 2.86Å; V58-S62 WeakPolarHBondContact O-CB 3.39Å; V58-S62 PolarHBondContact O-N 2.92Å; V58-S62 PolarHBondContact O-OG 3.21Å; I59-S62 PolarHBondContact O-N 3.25Å; I59-S62 PolarHBondContact O-OG 2.97Å; A60-S62 PolarHBondContact O-N 2.95Å; S62-G66 PolarHBondContact O-N 2.89Å; S62-G66 VanDerWaalsContact O-N 3.14Å
63L98.1Very high97.7Very high12 Ų1243 Ų436%0.06325%0.248CC..Hα-helixtrans-68.3-41.8175-67173.2000111.8M6 I59 A60 G61 G67 L68 P70 I73 Y232M6-L63 HydrophobicContact CE-CD1 4.4Å; M6-L63 HydrophobicContact CE-CD2 3.74Å; M6-L63 HydrophobicContact CE-CG 3.87Å; I59-L63 HydrophobicContact CG2-CD1 4.35Å; I59-L63 WeakPolarHBondContact O-CG 3.27Å; I59-L63 PolarHBondContact O-N 3.32Å; A60-L63 PolarHBondContact O-N 3.18Å; G61-L63 VanDerWaalsContact C-N 3.34Å; G61-L63 PolarHBondContact O-N 3.29Å; L63-G67 PolarHBondContact O-N 3.33Å; L63-G67 VanDerWaalsContact O-N 3.11Å; L63-L68 HydrophobicContact CD2-CB 4.14Å; L63-L68 PolarHBondContact O-N 3.13Å; L63-P70 HydrophobicContact CD1-CG 4.22Å; L63-I73 HydrophobicContact CD2-CD1 4.12Å; L63-I73 HydrophobicContact CD2-CG1 4.14Å; L63-Y232 HydrophobicContact CD1-CD2 3.9Å; L63-Y232 HydrophobicContact CD1-CE2 3.45Å; L63-Y232 VanDerWaalsContact CD1-CE2 3.45Å
64I97.9Very high97.7Very high134 Ų13442.5 Ų42.569%0.68724%0.243SC*.Hα-helixtrans-64.6-49.5178-69.7165.2000110.8A60 G61 G66 G67A60-I64 WeakPolarHBondContact O-CD1 3.05Å; A60-I64 VanDerWaalsContact O-CG1 3.23Å; A60-I64 WeakPolarHBondContact O-CG1 3.47Å; A60-I64 PolarHBondContact O-N 2.8Å; G61-I64 PolarHBondContact O-N 3.46Å; I64-G66 VanDerWaalsContact C-N 3.31Å; I64-G66 PolarHBondContact O-N 2.81Å; I64-G67 PolarHBondContact O-N 3.02Å; I64-G67 VanDerWaalsContact O-N 3.12Å
65E96.8Very high97.7Very high133 Ų13342.3 Ų42.362%0.62124%0.242SC*.Hα-helixtrans-62.9-37.9-178.2-73.8-174-153.200112G61 G67G61-E65 WeakPolarHBondContact O-CB 3.48Å; G61-E65 WeakPolarHBondContact O-CG 3.37Å; G61-E65 PolarHBondContact O-N 3.27Å; E65-G67 VanDerWaalsContact C-N 3.32Å
66G95.9Very high97.7Very high24 Ų2442.3 Ų42.325%0.24724%0.242CC..Hα-helixtrans-79.9-9.1176.200000114.7S62 I64 L68S62-G66 PolarHBondContact O-N 2.89Å; S62-G66 VanDerWaalsContact O-N 3.14Å; I64-G66 VanDerWaalsContact C-N 3.31Å; I64-G66 PolarHBondContact O-N 2.81Å; G66-L68 WeakPolarHBondContact O-CD2 3.34Å; G66-L68 PolarHBondContact O-N 3.15Å
67G96.8Very high97.7Very high66 Ų6639 Ų3968%0.6823%0.226SC*.THydrogen-bonded Turntrans59.830.1-171.200000113.1L63 I64 E65L63-G67 PolarHBondContact O-N 3.33Å; L63-G67 VanDerWaalsContact O-N 3.11Å; I64-G67 PolarHBondContact O-N 3.02Å; I64-G67 VanDerWaalsContact O-N 3.12Å; E65-G67 VanDerWaalsContact C-N 3.32Å
68L97.2Very high97.7Very high20 Ų2037 Ų3711%0.10521%0.213CC..  trans-93.9146.2-171.6-57.6-178.7000111.2Y4 V19 V27 L63 G66Y4-L68 HydrophobicContact CD2-CD1 4.09Å; Y4-L68 HydrophobicContact CD2-CD2 4.12Å; Y4-L68 HydrophobicContact CE2-CD1 4.3Å; Y4-L68 HydrophobicContact CE2-CD2 3.52Å; Y4-L68 HydrophobicContact CE2-CG 4.49Å; Y4-L68 HydrophobicContact CG-CD1 4.37Å; V19-L68 HydrophobicContact CB-CD1 4.08Å; V19-L68 HydrophobicContact CG1-CD1 3.53Å; V19-L68 HydrophobicContact CG2-CD1 4.25Å; V27-L68 HydrophobicContact CG1-CD1 4.28Å; V27-L68 HydrophobicContact CG1-CD2 4.48Å; L63-L68 HydrophobicContact CD2-CB 4.14Å; L63-L68 PolarHBondContact O-N 3.13Å; G66-L68 WeakPolarHBondContact O-CD2 3.34Å; G66-L68 PolarHBondContact O-N 3.15Å
69K96.6Very high97.7Very high119 Ų11937 Ų3752%0.51721%0.213SC..  trans-88.6144.5169.2-61.8-179.5-178.9-178.90110.4D71 Q72K69-D71 WeakPolarHBondContact CB-OD1 3.33Å; K69-D71 PolarHBondContact O-N 3.03Å; K69-Q72 HydrophobicContact CB-CG 4.15Å; K69-Q72 VanDerWaalsContact O-CB 3.31Å; K69-Q72 WeakPolarHBondContact O-CB 3.49Å; K69-Q72 PolarHBondContact O-N 3.01Å
70P96.2Very high97.8Very high28 Ų2836.8 Ų36.818%0.18221%0.212CC..G310 helixtrans-58.4-29.3178.9-2330.5000114.4L63 Q72 I73 F231 Y232L63-P70 HydrophobicContact CD1-CG 4.22Å; P70-Q72 PolarHBondContact O-N 3.02Å; P70-I73 PolarHBondContact O-N 2.76Å; P70-F231 HydrophobicContact CB-CD1 4.04Å; P70-F231 HydrophobicContact CB-CE1 3.93Å; P70-Y232 HydrophobicContact CB-CD2 4.02Å; P70-Y232 HydrophobicContact CB-CG 4.5Å; P70-Y232 HydrophobicContact CG-CD2 3.66Å; P70-Y232 HydrophobicContact CG-CG 3.86Å
71D96Very high97.7Very high87 Ų8735.4 Ų35.447%0.46520%0.201SC..G310 helixtrans-72.5-5.4176.664.9-15.5000113.8K69K69-D71 WeakPolarHBondContact CB-OD1 3.33Å; K69-D71 PolarHBondContact O-N 3.03Å
72Q97.6Very high97.7Very high27 Ų2734.9 Ų34.913%0.12619%0.194CC..G310 helixtrans-89-7.4173-58.9-178.2-100.200113M1 E2 S3 Y4 K69 P70M1-Q72 HydrophobicContact CG-CG 4.09Å; M1-Q72 HydrophobicContact SD-CG 3.9Å; E2-Q72 PolarHBondContact O-NE2 3.19Å; S3-Q72 CarbonylContact C-O 3.59Å; S3-Q72 VanDerWaalsContact CA-O 3.3Å; S3-Q72 WeakPolarHBondContact CA-O 3.42Å; Y4-Q72 HydrophobicContact CD2-CB 3.92Å; Y4-Q72 HydrophobicContact CE2-CB 4.2Å; Y4-Q72 PolarHBondContact N-O 3.22Å; K69-Q72 HydrophobicContact CB-CG 4.15Å; K69-Q72 VanDerWaalsContact O-CB 3.31Å; K69-Q72 WeakPolarHBondContact O-CB 3.49Å; K69-Q72 PolarHBondContact O-N 3.01Å; P70-Q72 PolarHBondContact O-N 3.02Å
73I98.3Very high97.7Very high8 Ų835 Ų354%0.04120%0.195CC..EExtended strand (participates in β ladder)trans-85.5112.1176.8-52.5-54.7000108.8Y4 M6 V19 L63 P70 G75 I76 F231 V236Y4-I73 CarbonylContact O-C 3.4Å; Y4-I73 WeakPolarHBondContact O-CA 3.36Å; M6-I73 HydrophobicContact CB-CD1 4.45Å; M6-I73 HydrophobicContact CB-CG2 3.78Å; M6-I73 HydrophobicContact CE-CD1 4.26Å; M6-I73 HydrophobicContact CE-CG1 4.29Å; V19-I73 HydrophobicContact CG1-CD1 4.07Å; V19-I73 HydrophobicContact CG2-CD1 4.42Å; L63-I73 HydrophobicContact CD2-CD1 4.12Å; L63-I73 HydrophobicContact CD2-CG1 4.14Å; P70-I73 PolarHBondContact O-N 2.76Å; I73-G75 WeakPolarHBondContact CG2-O 3.39Å; I73-I76 HydrophobicContact CG2-CG1 4.26Å; I73-F231 HydrophobicContact CB-CE1 4.28Å; I73-F231 HydrophobicContact CB-CZ 4.4Å; I73-F231 HydrophobicContact CG1-CE1 4.18Å; I73-F231 HydrophobicContact CG1-CZ 4.14Å; I73-F231 HydrophobicContact CG2-CZ 4.47Å; I73-V236 HydrophobicContact CB-CG1 4.24Å; I73-V236 HydrophobicContact CG2-CG1 3.81Å
74E98Very high97.7Very high73 Ų7334.4 Ų34.434%0.34119%0.192SC..EExtended strand (participates in β ladder)trans-81-22.1-180-89.1-174.4-149.900113S3 Y4 I5 P237 Y452S3-E74 WeakPolarHBondContact CB-OE1 3.18Å; S3-E74 PolarHBondContact OG-OE1 3.23Å; Y4-E74 PolarHBondContact O-N 3.27Å; I5-E74 HydrophobicContact CD1-CB 4.27Å; E74-P237 WeakPolarHBondContact O-CD 3.24Å; E74-P237 WeakPolarHBondContact O-CG 3.38Å; E74-Y452 HydrophobicContact CB-CD2 4.35Å; E74-Y452 VanDerWaalsContact OE2-CD2 3.32Å; E74-Y452 WeakPolarHBondContact OE2-CD2 3.35Å
75G98.5Very high97.8Very high0 Ų028 Ų280%016%0.159CC..EExtended strand (participates in β ladder)trans-170.5158.3176.900000113.4M6 I73 P237M6-G75 PolarHBondContact N-O 3.17Å; I73-G75 WeakPolarHBondContact CG2-O 3.39Å; G75-P237 WeakPolarHBondContact CA-O 3.39Å
76I98.9Very high97.9Very high0 Ų021.7 Ų21.70%013%0.13CC..EExtended strand (participates in β ladder)trans-115.7128178.5-62.7165.9000109.8M6 I8 I73 I78 T226 F231 V236 P237 A239 G240M6-I76 HydrophobicContact CB-CG1 4.36Å; M6-I76 CarbonylContact O-C 3.58Å; M6-I76 VanDerWaalsContact O-CA 3.27Å; M6-I76 WeakPolarHBondContact O-CA 3.45Å; I8-I76 HydrophobicContact CD1-CG2 3.76Å; I8-I76 HydrophobicContact CG1-CG2 4.26Å; I73-I76 HydrophobicContact CG2-CG1 4.26Å; I76-I78 HydrophobicContact CG2-CG1 4.05Å; I76-T226 HydrophobicContact CD1-CG2 3.63Å; I76-F231 HydrophobicContact CD1-CD2 4.11Å; I76-F231 HydrophobicContact CD1-CE2 3.71Å; I76-F231 HydrophobicContact CD1-CZ 4.11Å; I76-V236 HydrophobicContact CD1-CB 4.08Å; I76-V236 HydrophobicContact CD1-CG1 3.78Å; I76-V236 HydrophobicContact CG1-CG1 3.75Å; I76-P237 PolarHBondContact N-O 2.92Å; I76-A239 PolarHBondContact O-N 2.87Å; I76-G240 PolarHBondContact O-N 3.45Å
77G98.9Very high98Very high0 Ų020.7 Ų20.70%012%0.118CC..EExtended strand (participates in β ladder)trans-103136.4166.200000111M6 S7 I8 G240M6-G77 PolarHBondContact O-N 3.12Å; S7-G77 CarbonylContact C-O 3.6Å; S7-G77 WeakPolarHBondContact CA-O 3.42Å; I8-G77 PolarHBondContact N-O 2.99Å; G77-G240 CarbonylContact C-O 3.56Å; G77-G240 WeakPolarHBondContact CA-O 3.29Å
78I98.9Very high98.1Very high0 Ų017.5 Ų17.50%09%0.086CC..EExtended strand (participates in β ladder)trans-118.7123.3-179.3-58.9174.8000109.2I8 I76 L168 V169 L172 I238 G240 M241 A242 V442I8-I78 HydrophobicContact CD1-CG1 4.47Å; I76-I78 HydrophobicContact CG2-CG1 4.05Å; I78-L168 HydrophobicContact CD1-CB 4.46Å; I78-L168 HydrophobicContact CG2-CB 4.33Å; I78-L168 HydrophobicContact CG2-CD1 3.89Å; I78-V169 HydrophobicContact CD1-CG2 3.7Å; I78-L172 HydrophobicContact CD1-CD1 3.63Å; I78-I238 HydrophobicContact CD1-CG2 3.63Å; I78-I238 HydrophobicContact CG1-CG2 4.22Å; I78-G240 PolarHBondContact N-O 2.86Å; I78-M241 HydrophobicContact CB-CG 4.31Å; I78-M241 WeakPolarHBondContact O-CA 3.46Å; I78-A242 PolarHBondContact O-N 3.37Å; I78-V442 WeakPolarHBondContact O-CG1 3.49Å
79T98.9Very high98.2Very high0 Ų018.9 Ų18.90%09%0.092CC..EExtended strand (participates in β ladder)trans-122.8151.9169.7179.70000110.3I8 D9 Q10 A242 D244 A247 T438 V442I8-T79 WeakPolarHBondContact O-CG2 3.38Å; I8-T79 PolarHBondContact O-N 3.46Å; I8-T79 VanDerWaalsContact O-O 3.14Å; D9-T79 WeakPolarHBondContact CA-O 3.48Å; D9-T79 HydrophobicContact CB-CG2 3.52Å; Q10-T79 PolarHBondContact N-O 2.85Å; T79-A242 VanDerWaalsContact CA-O 3.27Å; T79-A242 WeakPolarHBondContact CA-O 3.39Å; T79-A242 PolarHBondContact OG1-O 2.67Å; T79-D244 WeakPolarHBondContact OG1-CA 3.48Å; T79-D244 PolarHBondContact OG1-N 2.99Å; T79-A247 WeakPolarHBondContact OG1-CB 3.39Å; T79-T438 HydrophobicContact CG2-CG2 3.73Å; T79-T438 WeakPolarHBondContact OG1-CG2 3.06Å; T79-V442 HydrophobicContact CG2-CG1 4.37Å; T79-V442 HydrophobicContact CG2-CG2 3.58Å
80N98.8Very high98.3Very high0 Ų018.6 Ų18.60%09%0.091CC..EExtended strand (participates in β ladder)trans-151.6157-171.162.1-70.7000113.5Q10 R82 I164 D165 N184 D244Q10-N80 HydrophobicContact CB-CB 4.4Å; Q10-N80 CarbonylContact O-C 3.58Å; Q10-N80 VanDerWaalsContact O-CA 3.31Å; Q10-N80 WeakPolarHBondContact O-CA 3.38Å; N80-R82 PolarHBondContact O-N 2.91Å; N80-I164 HydrophobicContact CB-CB 3.73Å; N80-I164 HydrophobicContact CB-CG2 3.56Å; N80-D165 WeakPolarHBondContact OD1-CB 3.46Å; N80-N184 PolarHBondContact ND2-OD1 3.27Å; N80-N184 PolarHBondContact OD1-ND2 3.36Å; N80-N184 PolarHBondContact OD1-OD1 3.07Å; N80-D244 VanDerWaalsContact O-CB 3.25Å; N80-D244 WeakPolarHBondContact O-CB 3.3Å; N80-D244 VanDerWaalsContact O-CG 3.26Å; N80-D244 PolarHBondContact O-N 3.17Å
81Q97Very high98.3Very high0 Ų026.4 Ų26.40%012%0.124CC..  trans-53.6121.1158.559.2177.3-4900109.2Q10 H46 T84 I164Q10-Q81 PolarHBondContact O-N 2.9Å; H46-Q81 PolarHBondContact ND1-NE2 2.66Å; Q81-T84 PolarHBondContact OE1-OG1 2.94Å; Q81-T84 VanDerWaalsContact OE1-OG1 3.07Å; Q81-I164 HydrophobicContact CG-CG1 3.98Å
82R98.4Very high98.3Very high2 Ų225.4 Ų25.41%0.00812%0.122CC..SBendtrans-74.8168.2-178.3-62.2172.4-54.7149.616.8110.5N80 T84 Y134 R187 G243 D244 Q245 Q246 E302N80-R82 PolarHBondContact O-N 2.91Å; R82-T84 PolarHBondContact O-N 3.21Å; R82-Y134 PolarHBondContact NH2-OH 3.06Å; R82-R187 HydrophobicContact CB-CG 4.29Å; R82-G243 VanDerWaalsContact CG-CA 3.47Å; R82-D244 IonicContact NE-OD1 3.74Å; R82-D244 PolarHBondContact NE-OD1 2.85Å; R82-Q245 VanDerWaalsContact CZ-CG 3.42Å; R82-Q245 VanDerWaalsContact NH2-CG 3.3Å; R82-Q246 VanDerWaalsContact CD-OE1 3.25Å; R82-E302 IonicContact CZ-OE1 2.99Å; R82-E302 IonicContact CZ-OE2 2.83Å; R82-E302 IonicContact NH1-OE1 3.16Å; R82-E302 PolarHBondContact NH1-OE1 3.33Å; R82-E302 IonicContact NH1-OE2 2.77Å; R82-E302 PolarHBondContact NH1-OE2 3.26Å; R82-E302 IonicContact NH2-OE1 2.67Å; R82-E302 PolarHBondContact NH2-OE1 3.45Å; R82-E302 IonicContact NH2-OE2 2.65Å
83E98.5Very high98.3Very high2 Ų224.5 Ų24.51%0.00912%0.12CC..SBendtrans62-33.3177.8-58.382-157.600117.3T85 W102 Y134 F135 S136 R187E83-T85 PolarHBondContact O-N 2.98Å; E83-T85 PolarHBondContact O-OG1 3.25Å; E83-W102 HydrophobicContact CB-CB 3.85Å; E83-Y134 VanDerWaalsContact CB-O 3.3Å; E83-Y134 WeakPolarHBondContact CB-O 3.33Å; E83-Y134 VanDerWaalsContact CD-CZ 3.48Å; E83-Y134 HydrophobicContact CG-CD2 4.26Å; E83-Y134 HydrophobicContact CG-CE2 4.02Å; E83-Y134 PolarHBondContact OE1-OH 3.04Å; E83-Y134 WeakPolarHBondContact OE2-CE2 3.48Å; E83-Y134 VanDerWaalsContact OE2-CZ 3.23Å; E83-Y134 PolarHBondContact OE2-OH 3.26Å; E83-F135 HydrophobicContact CG-CD1 3.94Å; E83-S136 WeakPolarHBondContact CA-OG 3.4Å; E83-S136 PolarHBondContact O-OG 3.37Å; E83-R187 HydrophobicContact CG-CB 4.08Å; E83-R187 VanDerWaalsContact OE1-CB 3.3Å; E83-R187 WeakPolarHBondContact OE1-CB 3.31Å; E83-R187 WeakPolarHBondContact OE1-CG 3.43Å; E83-R187 IonicContact OE1-CZ 3.87Å; E83-R187 IonicContact OE1-NE 3.13Å; E83-R187 PolarHBondContact OE1-NE 2.82Å; E83-R187 IonicContact OE1-NH2 3.82Å; E83-R187 PolarHBondContact OE1-NH2 3.46Å
84T98.8Very high98.3Very high0 Ų029.4 Ų29.40%014%0.142CC..  trans-50.9123-179.9-68.40000110.3Q81 R82 A99 I100 V101 W102 T163 I164Q81-T84 PolarHBondContact OE1-OG1 2.94Å; Q81-T84 VanDerWaalsContact OE1-OG1 3.07Å; R82-T84 PolarHBondContact O-N 3.21Å; T84-A99 HydrophobicContact CG2-CB 4.03Å; T84-I100 WeakPolarHBondContact CA-O 3.35Å; T84-V101 HydrophobicContact CG2-CG2 4.47Å; T84-V101 WeakPolarHBondContact OG1-CA 3.42Å; T84-W102 PolarHBondContact OG1-N 3.2Å; T84-T163 WeakPolarHBondContact O-CA 3.32Å; T84-I164 HydrophobicContact CG2-CD1 3.78Å; T84-I164 HydrophobicContact CG2-CG1 3.86Å
85T99Very high98.3Very high0 Ų027.3 Ų27.30%014%0.135CC..BIsolated β-bridgetrans-110.3128-162.6-69.80000111.1E83 A99 I100 S136 K139 V140 I143 F161E83-T85 PolarHBondContact O-N 2.98Å; E83-T85 PolarHBondContact O-OG1 3.25Å; T85-A99 CarbonylContact O-C 3.56Å; T85-A99 WeakPolarHBondContact O-CA 3.36Å; T85-I100 PolarHBondContact N-O 2.88Å; T85-I100 PolarHBondContact O-N 3.17Å; T85-I100 VanDerWaalsContact O-N 3.08Å; T85-S136 WeakPolarHBondContact OG1-CA 3.48Å; T85-S136 VanDerWaalsContact OG1-CB 3.26Å; T85-S136 WeakPolarHBondContact OG1-CB 3.24Å; T85-K139 HydrophobicContact CG2-CB 4.09Å; T85-V140 HydrophobicContact CG2-CG2 3.67Å; T85-I143 HydrophobicContact CG2-CD1 4.16Å; T85-F161 HydrophobicContact CG2-CD2 3.94Å; T85-F161 HydrophobicContact CG2-CE2 3.73Å
86V98.9Very high98.3Very high0 Ų028.6 Ų28.60%014%0.142CC..EExtended strand (participates in β ladder)trans-119.7137.7173.5-164.40000109.1A48 W88 P95 A99 F161 G162 I164 W167A48-V86 HydrophobicContact CB-CG1 3.75Å; A48-V86 HydrophobicContact CB-CG2 4.29Å; V86-W88 HydrophobicContact CB-CE3 4.12Å; V86-W88 HydrophobicContact CB-CZ3 4.22Å; V86-W88 HydrophobicContact CG1-CE3 3.94Å; V86-W88 HydrophobicContact CG1-CZ3 4.5Å; V86-P95 HydrophobicContact CG1-CB 4.46Å; V86-A99 HydrophobicContact CG2-CB 3.84Å; V86-F161 WeakPolarHBondContact O-CA 3.28Å; V86-G162 PolarHBondContact N-O 3.07Å; V86-G162 PolarHBondContact O-N 2.67Å; V86-I164 HydrophobicContact CG2-CD1 3.84Å; V86-W167 HydrophobicContact CG1-CD2 4.48Å; V86-W167 HydrophobicContact CG1-CE3 4.4Å; V86-W167 HydrophobicContact CG2-CB 4.39Å
87I98.9Very high98.3Very high2 Ų231.7 Ų31.71%0.0115%0.154CC..EExtended strand (participates in β ladder)trans-123.6130.3166.3-56.8-175.4000108P95 I96 V140 I143 L144 L159 L160I87-P95 WeakPolarHBondContact O-CA 3.36Å; I87-I96 HydrophobicContact CB-CD1 4.14Å; I87-I96 HydrophobicContact CB-CG1 3.95Å; I87-I96 HydrophobicContact CG2-CD1 3.69Å; I87-I96 HydrophobicContact CG2-CG1 3.85Å; I87-I96 WeakPolarHBondContact O-CG1 3.34Å; I87-I96 PolarHBondContact O-N 3.49Å; I87-V140 HydrophobicContact CD1-CG1 4.11Å; I87-I143 HydrophobicContact CB-CG2 4.43Å; I87-I143 HydrophobicContact CD1-CB 3.96Å; I87-I143 HydrophobicContact CD1-CD1 4.21Å; I87-I143 HydrophobicContact CD1-CG2 3.83Å; I87-I143 HydrophobicContact CG1-CD1 4.18Å; I87-I143 HydrophobicContact CG1-CG2 4.43Å; I87-L144 HydrophobicContact CD1-CD2 4.18Å; I87-L144 HydrophobicContact CD1-CG 4.27Å; I87-L159 HydrophobicContact CG2-CB 4.1Å; I87-L159 HydrophobicContact CG2-CD1 4.12Å; I87-L160 VanDerWaalsContact CA-O 3.26Å; I87-L160 WeakPolarHBondContact CA-O 3.44Å; I87-L160 WeakPolarHBondContact CG2-O 3.43Å
88W98.9Very high98.3Very high0 Ų034.1 Ų34.10%017%0.167CC..EExtended strand (participates in β ladder)trans-138.4162.4-177.567.294000112.1V86 H94 L159 L160 G162 T166 W167 W170 H178V86-W88 HydrophobicContact CB-CE3 4.12Å; V86-W88 HydrophobicContact CB-CZ3 4.22Å; V86-W88 HydrophobicContact CG1-CE3 3.94Å; V86-W88 HydrophobicContact CG1-CZ3 4.5Å; W88-H94 CarbonylContact C-O 3.58Å; W88-H94 VanDerWaalsContact CA-O 3.25Å; W88-H94 WeakPolarHBondContact CA-O 3.32Å; W88-H94 VanDerWaalsContact CB-O 3.31Å; W88-H94 WeakPolarHBondContact CB-O 3.41Å; W88-L159 CarbonylContact O-C 3.55Å; W88-L159 VanDerWaalsContact O-CA 3.31Å; W88-L159 WeakPolarHBondContact O-CA 3.33Å; W88-L160 HydrophobicContact CD2-CB 4.17Å; W88-L160 HydrophobicContact CH2-CB 4.22Å; W88-L160 HydrophobicContact CZ2-CB 3.63Å; W88-L160 HydrophobicContact CZ2-CD1 4.03Å; W88-L160 HydrophobicContact CZ2-CG 4.5Å; W88-L160 PolarHBondContact N-O 2.91Å; W88-L160 PolarHBondContact O-N 2.61Å; W88-G162 VanDerWaalsContact CZ3-N 3.3Å; W88-T166 HydrophobicContact CH2-CG2 3.86Å; W88-W167 HydrophobicContact CB-CZ3 4.06Å; W88-W167 AromaticContact CD2-CE3 3.86Å; W88-W167 HydrophobicContact CD2-CE3 3.86Å; W88-W167 AromaticContact CD2-CZ3 3.93Å; W88-W167 HydrophobicContact CD2-CZ3 3.93Å; W88-W167 AromaticContact CE3-CE3 3.86Å; W88-W167 HydrophobicContact CE3-CE3 3.86Å; W88-W167 HydrophobicContact CE3-CZ3 4.28Å; W88-W167 HydrophobicContact CG-CE3 4.25Å; W88-W167 AromaticContact CG-CZ3 3.81Å; W88-W167 HydrophobicContact CG-CZ3 3.81Å; W88-W167 HydrophobicContact CZ3-CE3 4.28Å; W88-W170 AromaticContact CD1-NE1 3.72Å; W88-W170 AromaticContact CE2-CD1 3.82Å; W88-W170 HydrophobicContact CZ2-CB 4.14Å; W88-W170 HydrophobicContact CZ2-CD2 4.28Å; W88-W170 AromaticContact CZ2-CG 3.93Å; W88-W170 HydrophobicContact CZ2-CG 3.93Å; W88-W170 AromaticContact NE1-CD1 3.29Å; W88-W170 VanDerWaalsContact NE1-CD1 3.29Å; W88-W170 AromaticContact NE1-CD2 3.91Å; W88-W170 AromaticContact NE1-CE2 3.51Å; W88-W170 AromaticContact NE1-CG 3.79Å; W88-W170 AromaticContact NE1-NE1 3.11Å; W88-W170 VanDerWaalsContact NE1-NE1 3.11Å; W88-H178 AromaticContact CH2-NE2 3.95Å; W88-H178 AromaticContact CZ2-CD2 3.81Å; W88-H178 AromaticContact CZ2-NE2 4Å
89E98.6Very high98.3Very high49 Ų4934.1 Ų34.123%0.22917%0.167CC..EExtended strand (participates in β ladder)trans-76.1128.9174.9-54.9-176.4165.300110.6E91 T92 G93 H94 I96 R153 L159E89-E91 PolarHBondContact O-N 3.18Å; E89-T92 WeakPolarHBondContact CB-OG1 3.29Å; E89-T92 WeakPolarHBondContact OE2-CG2 3.42Å; E89-T92 PolarHBondContact OE2-OG1 3.39Å; E89-G93 VanDerWaalsContact O-CA 3.25Å; E89-G93 WeakPolarHBondContact O-CA 3.48Å; E89-G93 PolarHBondContact O-N 3.07Å; E89-H94 PolarHBondContact N-O 3.42Å; E89-I96 HydrophobicContact CG-CG2 3.82Å; E89-R153 IonicContact OE1-CZ 3.3Å; E89-R153 IonicContact OE1-NH1 2.74Å; E89-R153 PolarHBondContact OE1-NH1 2.71Å; E89-R153 IonicContact OE1-NH2 3.82Å; E89-R153 PolarHBondContact OE1-NH2 3.11Å; E89-L159 HydrophobicContact CG-CD2 4.06Å
90K98.1Very high98.3Very high113 Ų11334.1 Ų34.149%0.49117%0.167SC..THydrogen-bonded Turntrans-60.3-42.6-178.1-176173.7-179.1174.70112.8E158 L160 W170K90-E158 PolarHBondContact N-O 3.15Å; K90-L160 HydrophobicContact CB-CD1 4.24Å; K90-L160 HydrophobicContact CB-CG 4.1Å; K90-L160 HydrophobicContact CD-CD2 4.36Å; K90-L160 HydrophobicContact CG-CD1 4.04Å; K90-L160 HydrophobicContact CG-CG 4.3Å; K90-W170 HydrophobicContact CG-CH2 4.38Å; K90-W170 HydrophobicContact CG-CZ2 4.45Å
91E96.7Very high98.2Very high191 Ų19134.1 Ų34.189%0.89317%0.167SC*.THydrogen-bonded Turntrans-76.7-42.4-174.8-63.9-171.1165.500113.2E89E89-E91 PolarHBondContact O-N 3.18Å
92T96.9Very high98.1Very high67 Ų6734.7 Ų34.741%0.41117%0.169SC..THydrogen-bonded Turntrans-93.4-22.1-174.7710000112.7E89 H94E89-T92 WeakPolarHBondContact CB-OG1 3.29Å; E89-T92 WeakPolarHBondContact OE2-CG2 3.42Å; E89-T92 PolarHBondContact OE2-OG1 3.39Å; T92-H94 PolarHBondContact O-N 3.4Å; T92-H94 WeakPolarHBondContact OG1-CB 3.34Å; T92-H94 PolarHBondContact OG1-N 3.02Å; T92-H94 PolarHBondContact OG1-ND1 3.38Å
93G96.8Very high97.8Very high8 Ų836.1 Ų36.18%0.08218%0.176CC..  trans69.214.5-172.100000113.7E89 W167E89-G93 VanDerWaalsContact O-CA 3.25Å; E89-G93 WeakPolarHBondContact O-CA 3.48Å; E89-G93 PolarHBondContact O-N 3.07Å; G93-W167 WeakPolarHBondContact O-CH2 3.48Å
94H98.2Very high97.5Very high110 Ų11036 Ų3651%0.50918%0.175SC..  trans-87.2130.9178.5-66.8151.4000111.7W88 E89 T92W88-H94 CarbonylContact C-O 3.58Å; W88-H94 VanDerWaalsContact CA-O 3.25Å; W88-H94 WeakPolarHBondContact CA-O 3.32Å; W88-H94 VanDerWaalsContact CB-O 3.31Å; W88-H94 WeakPolarHBondContact CB-O 3.41Å; E89-H94 PolarHBondContact N-O 3.42Å; T92-H94 PolarHBondContact O-N 3.4Å; T92-H94 WeakPolarHBondContact OG1-CB 3.34Å; T92-H94 PolarHBondContact OG1-N 3.02Å; T92-H94 PolarHBondContact OG1-ND1 3.38Å
95P98.8Very high97.2Very high29 Ų2937.6 Ų37.619%0.18818%0.182CC..BIsolated β-bridgetrans-59.9138.9170.2-2132.4000111.7A48 V86 I87 Y97 W167A48-P95 HydrophobicContact CB-CB 4.42Å; A48-P95 HydrophobicContact CB-CG 3.78Å; V86-P95 HydrophobicContact CG1-CB 4.46Å; I87-P95 WeakPolarHBondContact O-CA 3.36Å; P95-Y97 VanDerWaalsContact C-N 3.35Å; P95-Y97 WeakPolarHBondContact CB-O 3.48Å; P95-W167 HydrophobicContact CG-CH2 3.96Å; P95-W167 HydrophobicContact CG-CZ2 4.35Å
96I98.6Very high97Very high28 Ų2838.1 Ų38.114%0.14419%0.185CC..SBendtrans-85.9-11.8177.164.2158000113.1I87 E89 I143 V147 L159I87-I96 HydrophobicContact CB-CD1 4.14Å; I87-I96 HydrophobicContact CB-CG1 3.95Å; I87-I96 HydrophobicContact CG2-CD1 3.69Å; I87-I96 HydrophobicContact CG2-CG1 3.85Å; I87-I96 WeakPolarHBondContact O-CG1 3.34Å; I87-I96 PolarHBondContact O-N 3.49Å; E89-I96 HydrophobicContact CG-CG2 3.82Å; I96-I143 HydrophobicContact CD1-CG2 3.74Å; I96-I143 HydrophobicContact CG1-CG2 4.19Å; I96-V147 HydrophobicContact CB-CG1 4.43Å; I96-V147 HydrophobicContact CD1-CB 4.28Å; I96-V147 HydrophobicContact CD1-CG1 4.09Å; I96-V147 HydrophobicContact CD1-CG2 4.46Å; I96-L159 HydrophobicContact CD1-CD1 3.85Å; I96-L159 HydrophobicContact CG2-CD2 3.74Å
97Y98.6Very high96.9Very high65 Ų6538.2 Ų38.226%0.25519%0.185SC..SBendtrans-156.8166.9178.3-165.4-112.4000108.7E45 P95 I100 W142 I143 V147E45-Y97 PolarHBondContact OE1-OH 2.97Å; P95-Y97 VanDerWaalsContact C-N 3.35Å; P95-Y97 WeakPolarHBondContact CB-O 3.48Å; Y97-I100 HydrophobicContact CD1-CG1 4.28Å; Y97-I100 HydrophobicContact CE1-CD1 4.45Å; Y97-I100 HydrophobicContact CE1-CG1 4.15Å; Y97-W142 HydrophobicContact CD1-CZ3 4.16Å; Y97-W142 HydrophobicContact CE1-CE3 4.44Å; Y97-W142 HydrophobicContact CE1-CH2 4.17Å; Y97-W142 AromaticContact CE1-CZ3 3.54Å; Y97-W142 HydrophobicContact CE1-CZ3 3.54Å; Y97-W142 HydrophobicContact CE2-CH2 4.47Å; Y97-W142 HydrophobicContact CE2-CZ3 4.24Å; Y97-W142 AromaticContact CZ-CH2 3.8Å; Y97-W142 AromaticContact CZ-CZ3 3.57Å; Y97-W142 WeakPolarHBondContact OH-CH2 3.49Å; Y97-I143 HydrophobicContact CD1-CD1 4.45Å; Y97-I143 HydrophobicContact CD1-CG1 4.12Å; Y97-V147 HydrophobicContact CD2-CG2 4.08Å; Y97-V147 HydrophobicContact CG-CG2 4.24Å
98N98.7Very high96.7Very high51 Ų5138.9 Ų38.927%0.27319%0.19SC..PPolyproline II helixtrans-59.1152.9166.7-77-15.8000110.5E45 H46 I100E45-N98 HydrophobicContact CB-CB 3.96Å; E45-N98 HydrophobicContact CG-CB 4.21Å; E45-N98 WeakPolarHBondContact OE2-CB 3.05Å; E45-N98 PolarHBondContact OE2-ND2 3.41Å; H46-N98 CarbonylContact O-C 3.59Å; N98-I100 PolarHBondContact O-N 3.38Å
99A98.9Very high96.5Very high0 Ų045.2 Ų45.20%022%0.224CC..EExtended strand (participates in β ladder)trans-65.8126170.300000109.5E45 H46 T84 T85 V86 V101E45-A99 VanDerWaalsContact CA-O 3.3Å; E45-A99 WeakPolarHBondContact CA-O 3.31Å; H46-A99 HydrophobicContact CB-CB 4.35Å; H46-A99 PolarHBondContact N-O 3.45Å; H46-A99 WeakPolarHBondContact O-CB 3.2Å; H46-A99 PolarHBondContact O-N 2.94Å; T84-A99 HydrophobicContact CG2-CB 4.03Å; T85-A99 CarbonylContact O-C 3.56Å; T85-A99 WeakPolarHBondContact O-CA 3.36Å; V86-A99 HydrophobicContact CG2-CB 3.84Å; A99-V101 PolarHBondContact O-N 2.82Å
100I98.8Very high96.5Very high0 Ų043.8 Ų43.80%022%0.218CC..EExtended strand (participates in β ladder)trans-82.5117.1173.9-60.9172.1000107.7T84 T85 Y97 N98 Q106 K139 W142 I143T84-I100 WeakPolarHBondContact CA-O 3.35Å; T85-I100 PolarHBondContact N-O 2.88Å; T85-I100 PolarHBondContact O-N 3.17Å; T85-I100 VanDerWaalsContact O-N 3.08Å; Y97-I100 HydrophobicContact CD1-CG1 4.28Å; Y97-I100 HydrophobicContact CE1-CD1 4.45Å; Y97-I100 HydrophobicContact CE1-CG1 4.15Å; N98-I100 PolarHBondContact O-N 3.38Å; I100-Q106 HydrophobicContact CD1-CG 4.43Å; I100-Q106 HydrophobicContact CG2-CG 4.05Å; I100-Q106 VanDerWaalsContact CG2-OE1 3.31Å; I100-K139 HydrophobicContact CB-CB 4.1Å; I100-K139 HydrophobicContact CB-CD 4.16Å; I100-K139 HydrophobicContact CB-CG 4.27Å; I100-K139 HydrophobicContact CD1-CB 4.16Å; I100-K139 HydrophobicContact CG2-CB 4.1Å; I100-K139 HydrophobicContact CG2-CD 3.74Å; I100-K139 HydrophobicContact CG2-CG 3.76Å; I100-W142 HydrophobicContact CD1-CD2 4.29Å; I100-W142 HydrophobicContact CD1-CE3 3.66Å; I100-W142 HydrophobicContact CD1-CZ3 4.29Å; I100-I143 HydrophobicContact CD1-CD1 3.82Å; I100-I143 HydrophobicContact CD1-CG1 3.51Å; I100-I143 HydrophobicContact CG1-CD1 4.2Å; I100-I143 HydrophobicContact CG1-CG1 4.31Å
101V97.3Very high96.4Very high0 Ų038.4 Ų38.40%019%0.194CC..PPolyproline II helixtrans-76.8152.7-173.9-173.20000110.4T12 V44 H46 T84 A99 Q103 S104 K139T12-V101 HydrophobicContact CG2-CG1 4.16Å; V44-V101 HydrophobicContact CB-CB 4.05Å; V44-V101 HydrophobicContact CB-CG2 4.5Å; V44-V101 HydrophobicContact CG1-CB 3.82Å; V44-V101 HydrophobicContact CG1-CG1 4.1Å; V44-V101 HydrophobicContact CG1-CG2 3.97Å; V44-V101 WeakPolarHBondContact O-CB 3.35Å; V44-V101 WeakPolarHBondContact O-CG2 3.37Å; V44-V101 PolarHBondContact O-N 2.86Å; H46-V101 HydrophobicContact CB-CG2 4.24Å; H46-V101 WeakPolarHBondContact CE1-CG2 3.32Å; H46-V101 VanDerWaalsContact CG-CG2 3.5Å; H46-V101 VanDerWaalsContact ND1-CG2 3.31Å; H46-V101 WeakPolarHBondContact ND1-CG2 3.39Å; T84-V101 HydrophobicContact CG2-CG2 4.47Å; T84-V101 WeakPolarHBondContact OG1-CA 3.42Å; A99-V101 PolarHBondContact O-N 2.82Å; V101-Q103 HydrophobicContact CG1-CB 4.42Å; V101-Q103 HydrophobicContact CG1-CG 4.45Å; V101-Q103 PolarHBondContact O-N 3.2Å; V101-Q103 VanDerWaalsContact O-N 3.16Å; V101-S104 VanDerWaalsContact O-CB 3.23Å; V101-S104 WeakPolarHBondContact O-CB 3.41Å; V101-S104 PolarHBondContact O-N 3.13Å; V101-K139 PolarHBondContact O-NZ 2.82Å
102W94.6Very high96.4Very high11 Ų1131.7 Ų31.74%0.04216%0.164CC..THydrogen-bonded Turntrans-52.2-33.5175.369.2-96.8000113.8T12 E83 T84 S104 Y134 F269 F306T12-W102 HydrophobicContact CG2-CZ2 4.43Å; T12-W102 PolarHBondContact OG1-NE1 3.03Å; E83-W102 HydrophobicContact CB-CB 3.85Å; T84-W102 PolarHBondContact OG1-N 3.2Å; W102-S104 VanDerWaalsContact C-N 3.27Å; W102-S104 PolarHBondContact O-N 3.47Å; W102-Y134 HydrophobicContact CB-CD2 3.95Å; W102-Y134 HydrophobicContact CB-CE2 3.74Å; W102-Y134 HydrophobicContact CD2-CE2 4.04Å; W102-Y134 AromaticContact CE3-CD2 3.97Å; W102-Y134 HydrophobicContact CE3-CD2 3.97Å; W102-Y134 AromaticContact CE3-CE2 3.54Å; W102-Y134 HydrophobicContact CE3-CE2 3.54Å; W102-Y134 HydrophobicContact CG-CE2 4.17Å; W102-Y134 HydrophobicContact CZ3-CE2 4.46Å; W102-F269 HydrophobicContact CH2-CZ 4.24Å; W102-F269 HydrophobicContact CZ3-CZ 4.49Å; W102-F306 AromaticContact CZ3-CD1 3.98Å; W102-F306 HydrophobicContact CZ3-CD1 3.98Å
103Q90.6Very high96.4Very high32 Ų3233.2 Ų33.215%0.1517%0.167CC..THydrogen-bonded Turntrans-69.9-20177.2-63.4-179.3-4200114.1V44 V101 K105V44-Q103 HydrophobicContact CB-CB 4.11Å; V44-Q103 HydrophobicContact CG1-CB 4.35Å; V44-Q103 HydrophobicContact CG2-CB 3.81Å; V101-Q103 HydrophobicContact CG1-CB 4.42Å; V101-Q103 HydrophobicContact CG1-CG 4.45Å; V101-Q103 PolarHBondContact O-N 3.2Å; V101-Q103 VanDerWaalsContact O-N 3.16Å; Q103-K105 PolarHBondContact O-N 3.37Å
104S93.4Very high96.5Very high0 Ų033.3 Ų33.30%017%0.165CC..  trans-67.2131.3-172.8-167.90000111.6V44 V101 W102 Q106V44-S104 PolarHBondContact N-OG 3.34Å; V44-S104 WeakPolarHBondContact O-CB 3.29Å; V101-S104 VanDerWaalsContact O-CB 3.23Å; V101-S104 WeakPolarHBondContact O-CB 3.41Å; V101-S104 PolarHBondContact O-N 3.13Å; W102-S104 VanDerWaalsContact C-N 3.27Å; W102-S104 PolarHBondContact O-N 3.47Å; S104-Q106 WeakPolarHBondContact OG-CG 3.29Å; S104-Q106 PolarHBondContact OG-N 2.94Å; S104-Q106 PolarHBondContact OG-OE1 3.46Å
105K91.9Very high96.4Very high33 Ų3331.6 Ų31.614%0.14316%0.156CC..  trans-9711.4173.2-61.7-57-175.2-1760112.9G42 Q103 T107 S108 D132 S133 T348G42-K105 PolarHBondContact O-N 3.3Å; Q103-K105 PolarHBondContact O-N 3.37Å; K105-T107 PolarHBondContact O-N 3.18Å; K105-S108 WeakPolarHBondContact O-CB 3.4Å; K105-S108 PolarHBondContact O-N 2.9Å; K105-S108 VanDerWaalsContact O-N 3.16Å; K105-S108 PolarHBondContact O-OG 3.25Å; K105-D132 IonicContact NZ-OD1 3.78Å; K105-D132 PolarHBondContact NZ-OD1 3.34Å; K105-D132 VanDerWaalsContact NZ-OD1 3.16Å; K105-S133 WeakPolarHBondContact CD-OG 3.43Å; K105-S133 PolarHBondContact NZ-OG 3.28Å; K105-T348 VanDerWaalsContact CE-O 3.23Å; K105-T348 WeakPolarHBondContact CE-O 3.46Å
106Q95.2Very high96.3Very high12 Ų1238.3 Ų38.36%0.05619%0.185CC..THydrogen-bonded Turntrans-62.4-15.1-179.676.6-168.97700114.4W43 I100 S104W43-Q106 HydrophobicContact CD2-CB 3.53Å; W43-Q106 HydrophobicContact CE3-CB 4.12Å; W43-Q106 HydrophobicContact CG-CB 3.75Å; W43-Q106 HydrophobicContact CZ2-CB 3.93Å; I100-Q106 HydrophobicContact CD1-CG 4.43Å; I100-Q106 HydrophobicContact CG2-CG 4.05Å; I100-Q106 VanDerWaalsContact CG2-OE1 3.31Å; S104-Q106 WeakPolarHBondContact OG-CG 3.29Å; S104-Q106 PolarHBondContact OG-N 2.94Å; S104-Q106 PolarHBondContact OG-OE1 3.46Å
107T97.1Very high96.3Very high1 Ų141.8 Ų41.81%0.00620%0.201CC..THydrogen-bonded Turntrans-111.714.3-178.765.40000113.5K105 D109 I110 A111 S133 T138 K139 W142K105-T107 PolarHBondContact O-N 3.18Å; T107-D109 VanDerWaalsContact C-N 3.31Å; T107-D109 PolarHBondContact O-N 2.8Å; T107-I110 HydrophobicContact CG2-CD1 4.49Å; T107-I110 PolarHBondContact O-N 3.25Å; T107-A111 PolarHBondContact O-N 2.96Å; T107-A111 VanDerWaalsContact O-N 3.09Å; T107-S133 WeakPolarHBondContact OG1-CA 3.38Å; T107-S133 WeakPolarHBondContact OG1-CB 3.25Å; T107-T138 WeakPolarHBondContact CB-OG1 3.23Å; T107-T138 WeakPolarHBondContact CG2-O 3.28Å; T107-T138 PolarHBondContact OG1-OG1 2.83Å; T107-K139 HydrophobicContact CG2-CG 4.31Å; T107-W142 HydrophobicContact CG2-CB 3.6Å; T107-W142 HydrophobicContact CG2-CG 3.87Å
108S94Very high96.3Very high17 Ų1741.4 Ų41.412%0.11922%0.217CC..Hα-helixtrans-59.2-41179.1-75.60000112.3K105 I110 A111 D112 S133 Q357K105-S108 WeakPolarHBondContact O-CB 3.4Å; K105-S108 PolarHBondContact O-N 2.9Å; K105-S108 VanDerWaalsContact O-N 3.16Å; K105-S108 PolarHBondContact O-OG 3.25Å; S108-I110 VanDerWaalsContact C-N 3.31Å; S108-I110 PolarHBondContact O-N 2.81Å; S108-A111 CarbonylContact O-C 3.58Å; S108-A111 WeakPolarHBondContact O-CB 3.37Å; S108-A111 PolarHBondContact O-N 2.81Å; S108-A111 VanDerWaalsContact O-N 3.1Å; S108-D112 WeakPolarHBondContact O-CB 3.38Å; S108-D112 PolarHBondContact O-N 2.84Å; S108-S133 PolarHBondContact OG-OG 3.36Å; S108-S133 VanDerWaalsContact OG-OG 3.06Å; S108-Q357 PolarHBondContact OG-OE1 3.4Å
109D95.3Very high96.2Very high133 Ų13341.2 Ų41.271%0.71121%0.214SC*.Hα-helixtrans-61.8-38.8178.5-59.8-15000111.9T107 D112 E113T107-D109 VanDerWaalsContact C-N 3.31Å; T107-D109 PolarHBondContact O-N 2.8Å; D109-D112 PolarHBondContact O-N 3.5Å; D109-E113 WeakPolarHBondContact O-CB 3.32Å; D109-E113 PolarHBondContact O-N 2.74Å
110I97.9Very high96.2Very high19 Ų1943.3 Ų43.310%0.09723%0.229CC..Hα-helixtrans-64.6-43.9175-60.2172.3000110.1T107 S108 L114 T138 K141 W142T107-I110 HydrophobicContact CG2-CD1 4.49Å; T107-I110 PolarHBondContact O-N 3.25Å; S108-I110 VanDerWaalsContact C-N 3.31Å; S108-I110 PolarHBondContact O-N 2.81Å; I110-L114 HydrophobicContact CG2-CD1 4.27Å; I110-L114 WeakPolarHBondContact O-CD1 3.35Å; I110-L114 VanDerWaalsContact O-CG 3.26Å; I110-L114 WeakPolarHBondContact O-CG 3.29Å; I110-L114 PolarHBondContact O-N 2.79Å; I110-L114 VanDerWaalsContact O-N 3.16Å; I110-T138 HydrophobicContact CB-CG2 4.48Å; I110-T138 HydrophobicContact CG2-CG2 3.95Å; I110-K141 HydrophobicContact CD1-CG 4.26Å; I110-K141 HydrophobicContact CG2-CD 3.84Å; I110-W142 HydrophobicContact CD1-CB 3.85Å; I110-W142 HydrophobicContact CD1-CG 4.35Å
111A97.2Very high96.1Very high0 Ų048.2 Ų48.20%026%0.255CS..Hα-helixtrans-66.1-38.9178.200000112.2T107 S108 K115 I131 T138T107-A111 PolarHBondContact O-N 2.96Å; T107-A111 VanDerWaalsContact O-N 3.09Å; S108-A111 CarbonylContact O-C 3.58Å; S108-A111 WeakPolarHBondContact O-CB 3.37Å; S108-A111 PolarHBondContact O-N 2.81Å; S108-A111 VanDerWaalsContact O-N 3.1Å; A111-K115 WeakPolarHBondContact O-CE 2.88Å; A111-K115 WeakPolarHBondContact O-CG 3.27Å; A111-K115 PolarHBondContact O-N 3.36Å; A111-K115 VanDerWaalsContact O-N 3.14Å; A111-I131 HydrophobicContact CB-CG2 4.01Å; A111-I131 VanDerWaalsContact O-CG2 3.24Å; A111-I131 WeakPolarHBondContact O-CG2 3.34Å; A111-T138 HydrophobicContact CB-CG2 4.41Å
112D95.2Very high96.1Very high49 Ų4949.9 Ų49.926%0.26226%0.263SS..Hα-helixtrans-66.8-44.3177.7-71.6-14.4000111.1S108 D109 L114 K115 E116S108-D112 WeakPolarHBondContact O-CB 3.38Å; S108-D112 PolarHBondContact O-N 2.84Å; D109-D112 PolarHBondContact O-N 3.5Å; D112-L114 PolarHBondContact O-N 3.19Å; D112-K115 WeakPolarHBondContact O-CB 3.48Å; D112-K115 PolarHBondContact O-N 2.92Å; D112-K115 VanDerWaalsContact O-N 3.14Å; D112-K115 WeakPolarHBondContact OD1-CE 3.35Å; D112-K115 IonicContact OD1-NZ 3.59Å; D112-K115 PolarHBondContact OD1-NZ 2.64Å; D112-E116 WeakPolarHBondContact O-CG 3.3Å; D112-E116 PolarHBondContact O-N 2.86Å
113E97.4Very high96.3Very high100 Ų10049.4 Ų49.447%0.46726%0.262SS..Hα-helixtrans-57.9-45.1174.4-178.3177.7-172.300112.2D109 K115 E116 Q117D109-E113 WeakPolarHBondContact O-CB 3.32Å; D109-E113 PolarHBondContact O-N 2.74Å; E113-K115 VanDerWaalsContact C-N 3.31Å; E113-K115 PolarHBondContact O-N 3.14Å; E113-E116 PolarHBondContact O-N 2.81Å; E113-Q117 VanDerWaalsContact CG-NE2 3.3Å; E113-Q117 WeakPolarHBondContact O-CB 3.26Å; E113-Q117 VanDerWaalsContact O-CG 3.26Å; E113-Q117 WeakPolarHBondContact O-CG 3.16Å; E113-Q117 PolarHBondContact O-N 3.4Å; E113-Q117 PolarHBondContact OE1-NE2 3.42Å; E113-Q117 VanDerWaalsContact OE1-NE2 3.07Å
114L98.2Very high96.7Very high10 Ų1049.7 Ų49.75%0.05226%0.263CS..Hα-helixtrans-63.6-35.7177.6-68.7165.5000112.7I110 D112 G118 H119 I131 T138 M189 L205 L206I110-L114 HydrophobicContact CG2-CD1 4.27Å; I110-L114 WeakPolarHBondContact O-CD1 3.35Å; I110-L114 VanDerWaalsContact O-CG 3.26Å; I110-L114 WeakPolarHBondContact O-CG 3.29Å; I110-L114 PolarHBondContact O-N 2.79Å; I110-L114 VanDerWaalsContact O-N 3.16Å; D112-L114 PolarHBondContact O-N 3.19Å; L114-G118 PolarHBondContact O-N 3.17Å; L114-H119 WeakPolarHBondContact O-CB 3.26Å; L114-H119 PolarHBondContact O-N 2.87Å; L114-H119 VanDerWaalsContact O-N 3.16Å; L114-I131 HydrophobicContact CB-CD1 4.05Å; L114-I131 HydrophobicContact CB-CG2 3.92Å; L114-I131 HydrophobicContact CD1-CG2 4.21Å; L114-T138 HydrophobicContact CD1-CG2 4.24Å; L114-M189 HydrophobicContact CD1-CE 4.41Å; L114-L205 HydrophobicContact CD2-CD1 4.31Å; L114-L205 HydrophobicContact CD2-CD2 3.93Å; L114-L205 HydrophobicContact CD2-CG 4.02Å; L114-L206 HydrophobicContact CD1-CD2 3.74Å; L114-L206 HydrophobicContact CD2-CD2 3.92Å; L114-L206 HydrophobicContact CG-CD2 4.37Å
115K96.9Very high96.9Very high73 Ų7355.9 Ų55.932%0.31729%0.29SS..Hα-helixtrans-67.9-45.4174.5-76.2177.2-76.6172.50110.9A111 D112 E113 Q117 G118 I131A111-K115 WeakPolarHBondContact O-CE 2.88Å; A111-K115 WeakPolarHBondContact O-CG 3.27Å; A111-K115 PolarHBondContact O-N 3.36Å; A111-K115 VanDerWaalsContact O-N 3.14Å; D112-K115 WeakPolarHBondContact O-CB 3.48Å; D112-K115 PolarHBondContact O-N 2.92Å; D112-K115 VanDerWaalsContact O-N 3.14Å; D112-K115 WeakPolarHBondContact OD1-CE 3.35Å; D112-K115 IonicContact OD1-NZ 3.59Å; D112-K115 PolarHBondContact OD1-NZ 2.64Å; E113-K115 VanDerWaalsContact C-N 3.31Å; E113-K115 PolarHBondContact O-N 3.14Å; K115-Q117 VanDerWaalsContact C-N 3.25Å; K115-Q117 PolarHBondContact O-N 3.38Å; K115-G118 PolarHBondContact O-N 2.84Å; K115-I131 HydrophobicContact CD-CB 4.28Å; K115-I131 HydrophobicContact CD-CG2 4.47Å; K115-I131 HydrophobicContact CG-CB 3.78Å; K115-I131 HydrophobicContact CG-CD1 4.34Å; K115-I131 HydrophobicContact CG-CG2 3.9Å
116E97.2Very high97.2Very high170 Ų17055.9 Ų55.979%0.79429%0.29SS*.Hα-helixtrans-62.2-32.9177.6-72.1178.8179.700112.6D112 E113 G118D112-E116 WeakPolarHBondContact O-CG 3.3Å; D112-E116 PolarHBondContact O-N 2.86Å; E113-E116 PolarHBondContact O-N 2.81Å; E116-G118 PolarHBondContact O-N 3.22Å
117Q97.9Very high97.4Very high102 Ų10255.3 Ų55.348%0.47729%0.287SS..THydrogen-bonded Turntrans-76.8-3.5174.6-69.3172.25.200113.8E113 K115E113-Q117 VanDerWaalsContact CG-NE2 3.3Å; E113-Q117 WeakPolarHBondContact O-CB 3.26Å; E113-Q117 VanDerWaalsContact O-CG 3.26Å; E113-Q117 WeakPolarHBondContact O-CG 3.16Å; E113-Q117 PolarHBondContact O-N 3.4Å; E113-Q117 PolarHBondContact OE1-NE2 3.42Å; E113-Q117 VanDerWaalsContact OE1-NE2 3.07Å; K115-Q117 VanDerWaalsContact C-N 3.25Å; K115-Q117 PolarHBondContact O-N 3.38Å
118G98Very high97.4Very high57 Ų5755.3 Ų55.359%0.58829%0.287SS*.THydrogen-bonded Turntrans83.221.9173.300000115.1L114 K115 E116 S120L114-G118 PolarHBondContact O-N 3.17Å; K115-G118 PolarHBondContact O-N 2.84Å; E116-G118 PolarHBondContact O-N 3.22Å; G118-S120 VanDerWaalsContact C-N 3.34Å; G118-S120 PolarHBondContact O-N 2.95Å
119H98.4Very high97.6Very high47 Ų4754.5 Ų54.522%0.21828%0.281CS..  trans-82.9-4.8-177.1-64.9-59.2000114.9L114 D121 M122 I123 I131 L205L114-H119 WeakPolarHBondContact O-CB 3.26Å; L114-H119 PolarHBondContact O-N 2.87Å; L114-H119 VanDerWaalsContact O-N 3.16Å; H119-D121 PolarHBondContact O-N 2.52Å; H119-M122 HydrophobicContact CB-CE 4.45Å; H119-M122 PolarHBondContact O-N 2.77Å; H119-M122 VanDerWaalsContact O-N 3.16Å; H119-I123 HydrophobicContact CB-CG1 4.5Å; H119-I123 WeakPolarHBondContact O-CG1 3.09Å; H119-I123 PolarHBondContact O-N 3.16Å; H119-I131 HydrophobicContact CB-CD1 4.02Å; H119-L205 HydrophobicContact CB-CD2 4.22Å; H119-L205 WeakPolarHBondContact NE2-CD1 3.24Å
120S97.3Very high97.7Very high44 Ų4450.1 Ų50.131%0.30826%0.258SS..Hα-helixtrans-53.6-51.1-173.7-57.40000113.5G118 M122 I123 Q124G118-S120 VanDerWaalsContact C-N 3.34Å; G118-S120 PolarHBondContact O-N 2.95Å; S120-M122 VanDerWaalsContact C-N 3.33Å; S120-M122 PolarHBondContact O-N 3.49Å; S120-I123 PolarHBondContact O-N 2.91Å; S120-Q124 WeakPolarHBondContact O-CB 3.41Å; S120-Q124 PolarHBondContact O-N 2.92Å
121D97.1Very high97.6Very high103 Ų10349.6 Ų49.655%0.55126%0.255SS*.Hα-helixtrans-61.9-40.1-180-79.918.8000112.6H119 K125H119-D121 PolarHBondContact O-N 2.52Å; D121-K125 VanDerWaalsContact O-CB 3.3Å; D121-K125 WeakPolarHBondContact O-CB 3.23Å; D121-K125 WeakPolarHBondContact O-CD 3.45Å; D121-K125 VanDerWaalsContact O-CG 3.23Å; D121-K125 WeakPolarHBondContact O-CG 3.28Å; D121-K125 PolarHBondContact O-N 3.33Å
122M98.2Very high97.5Very high35 Ų3549.8 Ų49.817%0.17226%0.256CS..Hα-helixtrans-66.3-48.2-178.9178-82.1-78.700110.2H119 S120 Q124 K125 K126 I202 L205H119-M122 HydrophobicContact CB-CE 4.45Å; H119-M122 PolarHBondContact O-N 2.77Å; H119-M122 VanDerWaalsContact O-N 3.16Å; S120-M122 VanDerWaalsContact C-N 3.33Å; S120-M122 PolarHBondContact O-N 3.49Å; M122-Q124 PolarHBondContact O-N 3.41Å; M122-K125 PolarHBondContact O-N 3.48Å; M122-K126 HydrophobicContact CG-CD 4.12Å; M122-K126 WeakPolarHBondContact O-CG 3.49Å; M122-K126 PolarHBondContact O-N 2.95Å; M122-K126 HydrophobicContact SD-CD 3.45Å; M122-K126 WeakPolarHBondContact SD-CD 3.37Å; M122-K126 WeakPolarHBondContact SD-CE 3.46Å; M122-I202 HydrophobicContact CE-CG1 4.43Å; M122-I202 HydrophobicContact SD-CG1 4.03Å; M122-L205 HydrophobicContact CE-CD2 3.64Å
123I98.5Very high97.5Very high1 Ų147.5 Ų47.51%0.00524%0.244CC..Hα-helixtrans-60.7-47.3178.2-67.2-64.5000110.5H119 S120 K125 K126 T127 I131 M189 I202H119-I123 HydrophobicContact CB-CG1 4.5Å; H119-I123 WeakPolarHBondContact O-CG1 3.09Å; H119-I123 PolarHBondContact O-N 3.16Å; S120-I123 PolarHBondContact O-N 2.91Å; I123-K125 PolarHBondContact O-N 3.49Å; I123-K126 PolarHBondContact O-N 3.18Å; I123-T127 HydrophobicContact CG2-CG2 4.48Å; I123-T127 WeakPolarHBondContact O-CB 3.32Å; I123-T127 PolarHBondContact O-N 3.46Å; I123-T127 PolarHBondContact O-OG1 3.24Å; I123-I131 HydrophobicContact CB-CD1 4.23Å; I123-I131 HydrophobicContact CB-CG1 3.95Å; I123-I131 HydrophobicContact CG1-CD1 3.81Å; I123-I131 HydrophobicContact CG1-CG1 3.91Å; I123-I131 HydrophobicContact CG2-CG1 3.99Å; I123-M189 HydrophobicContact CG2-CG 3.58Å; I123-M189 HydrophobicContact CG2-SD 3.91Å; I123-I202 HydrophobicContact CD1-CB 4.43Å; I123-I202 HydrophobicContact CD1-CD1 3.7Å; I123-I202 HydrophobicContact CD1-CG1 3.74Å; I123-I202 HydrophobicContact CD1-CG2 3.93Å
124Q97.8Very high97.4Very high37 Ų3742.8 Ų42.817%0.17322%0.222CC..Hα-helixtrans-64.7-41.6-178.2-156.1-166.810.900112.1S120 M122 K126 G128 L129 L130 L280 S281S120-Q124 WeakPolarHBondContact O-CB 3.41Å; S120-Q124 PolarHBondContact O-N 2.92Å; M122-Q124 PolarHBondContact O-N 3.41Å; Q124-K126 PolarHBondContact O-N 3.09Å; Q124-G128 WeakPolarHBondContact O-CA 3.33Å; Q124-G128 PolarHBondContact O-N 3.3Å; Q124-L129 VanDerWaalsContact CA-O 3.24Å; Q124-L129 WeakPolarHBondContact CA-O 3.06Å; Q124-L130 HydrophobicContact CG-CD2 4.36Å; Q124-L280 HydrophobicContact CG-CD1 3.89Å; Q124-S281 PolarHBondContact NE2-O 2.87Å
125K97.7Very high97.4Very high130 Ų13042.3 Ų42.357%0.56522%0.219SC*.Hα-helixtrans-67.8-19.8178.6-76.1171-177.5161.50114.4D121 M122 I123 Y194D121-K125 VanDerWaalsContact O-CB 3.3Å; D121-K125 WeakPolarHBondContact O-CB 3.23Å; D121-K125 WeakPolarHBondContact O-CD 3.45Å; D121-K125 VanDerWaalsContact O-CG 3.23Å; D121-K125 WeakPolarHBondContact O-CG 3.28Å; D121-K125 PolarHBondContact O-N 3.33Å; M122-K125 PolarHBondContact O-N 3.48Å; I123-K125 PolarHBondContact O-N 3.49Å; K125-Y194 WeakPolarHBondContact O-CD2 3.21Å; K125-Y194 WeakPolarHBondContact O-CE2 3.44Å
126K98.5Very high97.5Very high34 Ų3438.9 Ų38.915%0.14820%0.204CC..Hα-helixtrans-98.3-41.1177.7-70.7165176.7-890112.5M122 I123 Q124 N192 I193 Y194 D199 E201 I202M122-K126 HydrophobicContact CG-CD 4.12Å; M122-K126 WeakPolarHBondContact O-CG 3.49Å; M122-K126 PolarHBondContact O-N 2.95Å; M122-K126 HydrophobicContact SD-CD 3.45Å; M122-K126 WeakPolarHBondContact SD-CD 3.37Å; M122-K126 WeakPolarHBondContact SD-CE 3.46Å; I123-K126 PolarHBondContact O-N 3.18Å; Q124-K126 PolarHBondContact O-N 3.09Å; K126-N192 CarbonylContact O-C 3.45Å; K126-N192 VanDerWaalsContact O-CA 3.29Å; K126-N192 WeakPolarHBondContact O-CA 3.38Å; K126-N192 PolarHBondContact O-OD1 3.11Å; K126-I193 PolarHBondContact O-N 3.39Å; K126-Y194 WeakPolarHBondContact O-CD2 3.46Å; K126-D199 WeakPolarHBondContact CD-OD2 3.5Å; K126-D199 VanDerWaalsContact NZ-CG 3.31Å; K126-D199 IonicContact NZ-OD1 2.98Å; K126-D199 PolarHBondContact NZ-OD1 3.13Å; K126-D199 IonicContact NZ-OD2 3.75Å; K126-D199 PolarHBondContact NZ-OD2 3.04Å; K126-E201 WeakPolarHBondContact CE-OE2 3.31Å; K126-E201 IonicContact NZ-OE2 3.03Å; K126-E201 PolarHBondContact NZ-OE2 3.39Å; K126-I202 HydrophobicContact CB-CD1 4.24Å; K126-I202 HydrophobicContact CD-CD1 4.04Å; K126-I202 HydrophobicContact CD-CG1 4.14Å
127T98.7Very high97.6Very high0 Ų030.8 Ų30.80%017%0.166CC..Hα-helixtrans-107.5-18.7-168.569.60000112.9I123 L129 I193 I202I123-T127 HydrophobicContact CG2-CG2 4.48Å; I123-T127 WeakPolarHBondContact O-CB 3.32Å; I123-T127 PolarHBondContact O-N 3.46Å; I123-T127 PolarHBondContact O-OG1 3.24Å; T127-L129 PolarHBondContact O-N 3.37Å; T127-L129 WeakPolarHBondContact OG1-CB 3.39Å; T127-L129 PolarHBondContact OG1-N 2.82Å; T127-L129 VanDerWaalsContact OG1-N 3.11Å; T127-I193 WeakPolarHBondContact O-CG2 3.32Å; T127-I202 HydrophobicContact CG2-CD1 3.53Å
128G98.2Very high97.6Very high0 Ų025.9 Ų25.90%014%0.144CC..SBendtrans74.2-0.6-169.700000114.4Q124 T287Q124-G128 WeakPolarHBondContact O-CA 3.33Å; Q124-G128 PolarHBondContact O-N 3.3Å; G128-T287 CarbonylContact C-O 3.6Å; G128-T287 VanDerWaalsContact CA-O 3.3Å; G128-T287 WeakPolarHBondContact CA-O 3.29Å; G128-T287 PolarHBondContact O-N 2.65Å
129L98.2Very high97.7Very high0 Ų023.2 Ų23.20%012%0.116CC..  trans-100.7160.9-176-48.7-178.6000112.2Q124 T127 F135 S186 M189 L286Q124-L129 VanDerWaalsContact CA-O 3.24Å; Q124-L129 WeakPolarHBondContact CA-O 3.06Å; T127-L129 PolarHBondContact O-N 3.37Å; T127-L129 WeakPolarHBondContact OG1-CB 3.39Å; T127-L129 PolarHBondContact OG1-N 2.82Å; T127-L129 VanDerWaalsContact OG1-N 3.11Å; L129-F135 HydrophobicContact CB-CD2 4.38Å; L129-F135 HydrophobicContact CB-CE1 4.43Å; L129-F135 HydrophobicContact CB-CE2 4Å; L129-F135 HydrophobicContact CB-CZ 4.01Å; L129-F135 HydrophobicContact CD1-CD1 3.65Å; L129-F135 HydrophobicContact CD1-CD2 4.26Å; L129-F135 HydrophobicContact CD1-CE1 3.82Å; L129-F135 HydrophobicContact CD1-CE2 4.43Å; L129-F135 HydrophobicContact CD1-CG 3.87Å; L129-F135 HydrophobicContact CD1-CZ 4.21Å; L129-F135 HydrophobicContact CD2-CE1 4.05Å; L129-F135 HydrophobicContact CD2-CZ 4.22Å; L129-F135 HydrophobicContact CG-CE1 4.33Å; L129-F135 HydrophobicContact CG-CZ 4.38Å; L129-S186 WeakPolarHBondContact CD1-O 3.44Å; L129-M189 HydrophobicContact CD1-CB 4.01Å; L129-M189 HydrophobicContact CD1-CG 4.47Å; L129-L286 HydrophobicContact CD2-CB 4.24Å; L129-L286 HydrophobicContact CD2-CD1 4.48Å; L129-L286 HydrophobicContact CD2-CD2 4.35Å
130L96.6Very high97.7Very high41 Ų4121 Ų2122%0.21511%0.105CC..  trans-88164.6167.2-57179.7000110.6Q124 D132 F135 L286 W355Q124-L130 HydrophobicContact CG-CD2 4.36Å; L130-D132 PolarHBondContact O-N 2.85Å; L130-F135 VanDerWaalsContact O-CD2 3.29Å; L130-F135 WeakPolarHBondContact O-CD2 3.33Å; L130-F135 WeakPolarHBondContact O-CE2 3.43Å; L130-L286 HydrophobicContact CG-CD2 4.27Å; L130-W355 HydrophobicContact CD1-CB 4.41Å; L130-W355 HydrophobicContact CD1-CD2 3.76Å; L130-W355 HydrophobicContact CD1-CG 3.6Å; L130-W355 HydrophobicContact CD1-CZ2 4.45Å
131I96.9Very high97.7Very high9 Ų920.7 Ų20.75%0.04610%0.099CC..  trans-84.2108172.5-59.2179.3000109.1A111 L114 K115 H119 I123A111-I131 HydrophobicContact CB-CG2 4.01Å; A111-I131 VanDerWaalsContact O-CG2 3.24Å; A111-I131 WeakPolarHBondContact O-CG2 3.34Å; L114-I131 HydrophobicContact CB-CD1 4.05Å; L114-I131 HydrophobicContact CB-CG2 3.92Å; L114-I131 HydrophobicContact CD1-CG2 4.21Å; K115-I131 HydrophobicContact CD-CB 4.28Å; K115-I131 HydrophobicContact CD-CG2 4.47Å; K115-I131 HydrophobicContact CG-CB 3.78Å; K115-I131 HydrophobicContact CG-CD1 4.34Å; K115-I131 HydrophobicContact CG-CG2 3.9Å; H119-I131 HydrophobicContact CB-CD1 4.02Å; I123-I131 HydrophobicContact CB-CD1 4.23Å; I123-I131 HydrophobicContact CB-CG1 3.95Å; I123-I131 HydrophobicContact CG1-CD1 3.81Å; I123-I131 HydrophobicContact CG1-CG1 3.91Å; I123-I131 HydrophobicContact CG2-CG1 3.99Å
132D95.3Very high97.8Very high4 Ų416.6 Ų16.62%0.0218%0.076CC..  trans-145.4159.4177.5-163.2-87.5000110.8K105 L130 Y134 F135 W355 Q357K105-D132 IonicContact NZ-OD1 3.78Å; K105-D132 PolarHBondContact NZ-OD1 3.34Å; K105-D132 VanDerWaalsContact NZ-OD1 3.16Å; L130-D132 PolarHBondContact O-N 2.85Å; D132-Y134 PolarHBondContact O-N 2.89Å; D132-Y134 WeakPolarHBondContact OD1-CB 3.42Å; D132-Y134 PolarHBondContact OD1-N 3.37Å; D132-F135 HydrophobicContact CB-CD2 4.39Å; D132-F135 HydrophobicContact CB-CE2 4.19Å; D132-W355 HydrophobicContact CB-CE3 4.33Å; D132-W355 HydrophobicContact CB-CZ3 4.21Å; D132-Q357 WeakPolarHBondContact OD2-CG 3.39Å; D132-Q357 PolarHBondContact OD2-NE2 2.88Å
133S95.1Very high97.8Very high0 Ų015 Ų150%07%0.068CC..THydrogen-bonded Turntrans-66.7-9.8171.348.80000113.4K105 T107 S108 F135 K139 Q357K105-S133 WeakPolarHBondContact CD-OG 3.43Å; K105-S133 PolarHBondContact NZ-OG 3.28Å; T107-S133 WeakPolarHBondContact OG1-CA 3.38Å; T107-S133 WeakPolarHBondContact OG1-CB 3.25Å; S108-S133 PolarHBondContact OG-OG 3.36Å; S108-S133 VanDerWaalsContact OG-OG 3.06Å; S133-F135 VanDerWaalsContact C-N 3.35Å; S133-F135 PolarHBondContact O-N 3.49Å; S133-K139 WeakPolarHBondContact O-CE 3.33Å; S133-K139 PolarHBondContact O-NZ 3.04Å; S133-Q357 PolarHBondContact OG-OE1 2.81Å
134Y95.3Very high97.9Very high2 Ų215.2 Ų15.21%0.0087%0.069CC..THydrogen-bonded Turntrans-57.1-42.5175-176.1-153000112.9R82 E83 W102 D132 K139 R187 L286 F306 W355R82-Y134 PolarHBondContact NH2-OH 3.06Å; E83-Y134 VanDerWaalsContact CB-O 3.3Å; E83-Y134 WeakPolarHBondContact CB-O 3.33Å; E83-Y134 VanDerWaalsContact CD-CZ 3.48Å; E83-Y134 HydrophobicContact CG-CD2 4.26Å; E83-Y134 HydrophobicContact CG-CE2 4.02Å; E83-Y134 PolarHBondContact OE1-OH 3.04Å; E83-Y134 WeakPolarHBondContact OE2-CE2 3.48Å; E83-Y134 VanDerWaalsContact OE2-CZ 3.23Å; E83-Y134 PolarHBondContact OE2-OH 3.26Å; W102-Y134 HydrophobicContact CB-CD2 3.95Å; W102-Y134 HydrophobicContact CB-CE2 3.74Å; W102-Y134 HydrophobicContact CD2-CE2 4.04Å; W102-Y134 AromaticContact CE3-CD2 3.97Å; W102-Y134 HydrophobicContact CE3-CD2 3.97Å; W102-Y134 AromaticContact CE3-CE2 3.54Å; W102-Y134 HydrophobicContact CE3-CE2 3.54Å; W102-Y134 HydrophobicContact CG-CE2 4.17Å; W102-Y134 HydrophobicContact CZ3-CE2 4.46Å; D132-Y134 PolarHBondContact O-N 2.89Å; D132-Y134 WeakPolarHBondContact OD1-CB 3.42Å; D132-Y134 PolarHBondContact OD1-N 3.37Å; Y134-K139 WeakPolarHBondContact O-CE 3.4Å; Y134-K139 PolarHBondContact O-NZ 3.26Å; Y134-R187 PolarHBondContact OH-NH2 3.13Å; Y134-L286 HydrophobicContact CE1-CD1 4.44Å; Y134-F306 HydrophobicContact CD1-CE1 4.25Å; Y134-F306 HydrophobicContact CE1-CE1 4.33Å; Y134-F306 HydrophobicContact CG-CE1 4.44Å; Y134-W355 HydrophobicContact CD1-CH2 4.06Å; Y134-W355 HydrophobicContact CD1-CZ3 4.2Å
135F98.2Very high97.9Very high0 Ų017 Ų170%08%0.079CC..SBendtrans-88.8157.8-169.3-50.7-65.9000114.5E83 L129 L130 D132 S133 A137 T138 R187 M189 L286 W355E83-F135 HydrophobicContact CG-CD1 3.94Å; L129-F135 HydrophobicContact CB-CD2 4.38Å; L129-F135 HydrophobicContact CB-CE1 4.43Å; L129-F135 HydrophobicContact CB-CE2 4Å; L129-F135 HydrophobicContact CB-CZ 4.01Å; L129-F135 HydrophobicContact CD1-CD1 3.65Å; L129-F135 HydrophobicContact CD1-CD2 4.26Å; L129-F135 HydrophobicContact CD1-CE1 3.82Å; L129-F135 HydrophobicContact CD1-CE2 4.43Å; L129-F135 HydrophobicContact CD1-CG 3.87Å; L129-F135 HydrophobicContact CD1-CZ 4.21Å; L129-F135 HydrophobicContact CD2-CE1 4.05Å; L129-F135 HydrophobicContact CD2-CZ 4.22Å; L129-F135 HydrophobicContact CG-CE1 4.33Å; L129-F135 HydrophobicContact CG-CZ 4.38Å; L130-F135 VanDerWaalsContact O-CD2 3.29Å; L130-F135 WeakPolarHBondContact O-CD2 3.33Å; L130-F135 WeakPolarHBondContact O-CE2 3.43Å; D132-F135 HydrophobicContact CB-CD2 4.39Å; D132-F135 HydrophobicContact CB-CE2 4.19Å; S133-F135 VanDerWaalsContact C-N 3.35Å; S133-F135 PolarHBondContact O-N 3.49Å; F135-A137 PolarHBondContact O-N 2.84Å; F135-T138 PolarHBondContact O-OG1 3.31Å; F135-R187 WeakPolarHBondContact CD1-O 3.3Å; F135-M189 HydrophobicContact CB-CB 3.77Å; F135-M189 HydrophobicContact CD2-SD 4.28Å; F135-M189 HydrophobicContact CG-CB 4.34Å; F135-L286 HydrophobicContact CE1-CD1 4.03Å; F135-L286 HydrophobicContact CZ-CD1 3.8Å; F135-L286 HydrophobicContact CZ-CD2 3.84Å; F135-L286 HydrophobicContact CZ-CG 4.49Å; F135-W355 HydrophobicContact CZ-CH2 4.31Å
136S98.9Very high97.9Very high0 Ų016.3 Ų16.30%08%0.078CC..Hα-helixtrans-63-35.6-169.9-48.30000114.9E83 T85 T138 K139 V140 T188E83-S136 WeakPolarHBondContact CA-OG 3.4Å; E83-S136 PolarHBondContact O-OG 3.37Å; T85-S136 WeakPolarHBondContact OG1-CA 3.48Å; T85-S136 VanDerWaalsContact OG1-CB 3.26Å; T85-S136 WeakPolarHBondContact OG1-CB 3.24Å; S136-T138 VanDerWaalsContact C-N 3.32Å; S136-T138 PolarHBondContact O-N 2.8Å; S136-K139 CarbonylContact O-C 3.5Å; S136-K139 WeakPolarHBondContact O-CA 3.23Å; S136-K139 VanDerWaalsContact O-CB 3.29Å; S136-K139 WeakPolarHBondContact O-CB 3Å; S136-K139 PolarHBondContact O-N 3.47Å; S136-V140 WeakPolarHBondContact O-CG2 3.34Å; S136-V140 PolarHBondContact O-N 3.42Å; S136-T188 PolarHBondContact N-O 3.36Å
137A98.8Very high97.9Very high0 Ų016 Ų160%08%0.079CC..Hα-helixtrans-54.6-45.5-171.600000113.1F135 K139 V140 K141 T188 M189 M190 L206F135-A137 PolarHBondContact O-N 2.84Å; A137-K139 VanDerWaalsContact C-N 3.3Å; A137-K139 PolarHBondContact O-N 2.8Å; A137-V140 PolarHBondContact O-N 2.86Å; A137-K141 PolarHBondContact O-N 3.17Å; A137-T188 VanDerWaalsContact CB-O 3.27Å; A137-T188 WeakPolarHBondContact CB-O 3.39Å; A137-T188 PolarHBondContact N-O 3.44Å; A137-M189 HydrophobicContact CB-CB 3.92Å; A137-M189 HydrophobicContact CB-CE 3.66Å; A137-M190 HydrophobicContact CB-CG 3.54Å; A137-M190 HydrophobicContact CB-SD 4.21Å; A137-L206 HydrophobicContact CB-CD1 3.55Å
138T98.6Very high97.8Very high0 Ų025 Ų250%012%0.121CC..Hα-helixtrans-69.3-30.5178.464.10000111.9T107 I110 A111 L114 F135 S136 W142 M189T107-T138 WeakPolarHBondContact CB-OG1 3.23Å; T107-T138 WeakPolarHBondContact CG2-O 3.28Å; T107-T138 PolarHBondContact OG1-OG1 2.83Å; I110-T138 HydrophobicContact CB-CG2 4.48Å; I110-T138 HydrophobicContact CG2-CG2 3.95Å; A111-T138 HydrophobicContact CB-CG2 4.41Å; L114-T138 HydrophobicContact CD1-CG2 4.24Å; F135-T138 PolarHBondContact O-OG1 3.31Å; S136-T138 VanDerWaalsContact C-N 3.32Å; S136-T138 PolarHBondContact O-N 2.8Å; T138-W142 VanDerWaalsContact O-CB 3.29Å; T138-W142 WeakPolarHBondContact O-CB 3.48Å; T138-W142 PolarHBondContact O-N 3.24Å; T138-M189 HydrophobicContact CG2-CE 4.12Å
139K98.8Very high97.8Very high0 Ų027.1 Ų27.10%014%0.143CC..Hα-helixtrans-69.7-43.2176.1-52.7175.6-165.5-67.60111.3T85 I100 V101 T107 S133 Y134 S136 A137 W142 I143T85-K139 HydrophobicContact CG2-CB 4.09Å; I100-K139 HydrophobicContact CB-CB 4.1Å; I100-K139 HydrophobicContact CB-CD 4.16Å; I100-K139 HydrophobicContact CB-CG 4.27Å; I100-K139 HydrophobicContact CD1-CB 4.16Å; I100-K139 HydrophobicContact CG2-CB 4.1Å; I100-K139 HydrophobicContact CG2-CD 3.74Å; I100-K139 HydrophobicContact CG2-CG 3.76Å; V101-K139 PolarHBondContact O-NZ 2.82Å; T107-K139 HydrophobicContact CG2-CG 4.31Å; S133-K139 WeakPolarHBondContact O-CE 3.33Å; S133-K139 PolarHBondContact O-NZ 3.04Å; Y134-K139 WeakPolarHBondContact O-CE 3.4Å; Y134-K139 PolarHBondContact O-NZ 3.26Å; S136-K139 CarbonylContact O-C 3.5Å; S136-K139 WeakPolarHBondContact O-CA 3.23Å; S136-K139 VanDerWaalsContact O-CB 3.29Å; S136-K139 WeakPolarHBondContact O-CB 3Å; S136-K139 PolarHBondContact O-N 3.47Å; A137-K139 VanDerWaalsContact C-N 3.3Å; A137-K139 PolarHBondContact O-N 2.8Å; K139-W142 PolarHBondContact O-N 3.11Å; K139-I143 WeakPolarHBondContact O-CG1 3.47Å; K139-I143 PolarHBondContact O-N 3.36Å
140V98.8Very high97.8Very high0 Ų027.2 Ų27.20%014%0.144CC..Hα-helixtrans-59.4-52.7173.2174.80000110T85 I87 S136 A137 W142 I143 L144 F161 M190 I208 I212T85-V140 HydrophobicContact CG2-CG2 3.67Å; I87-V140 HydrophobicContact CD1-CG1 4.11Å; S136-V140 WeakPolarHBondContact O-CG2 3.34Å; S136-V140 PolarHBondContact O-N 3.42Å; A137-V140 PolarHBondContact O-N 2.86Å; V140-W142 VanDerWaalsContact C-N 3.28Å; V140-W142 PolarHBondContact O-N 2.85Å; V140-I143 PolarHBondContact O-N 2.67Å; V140-L144 HydrophobicContact CG1-CD1 3.97Å; V140-L144 HydrophobicContact CG1-CG 4.4Å; V140-L144 WeakPolarHBondContact O-CG 2.93Å; V140-L144 PolarHBondContact O-N 3.4Å; V140-F161 HydrophobicContact CG2-CD2 3.36Å; V140-F161 HydrophobicContact CG2-CE2 3.39Å; V140-F161 HydrophobicContact CG2-CG 4.1Å; V140-F161 HydrophobicContact CG2-CZ 4.15Å; V140-M190 HydrophobicContact CG2-CE 4.11Å; V140-I208 HydrophobicContact CB-CD1 4.03Å; V140-I208 HydrophobicContact CG1-CD1 3.85Å; V140-I208 HydrophobicContact CG1-CG1 4.02Å; V140-I208 HydrophobicContact CG1-CG2 3.86Å; V140-I212 HydrophobicContact CG1-CD1 3.89Å
141K98.7Very high97.9Very high39 Ų3926.9 Ų26.917%0.1714%0.14CC..Hα-helixtrans-53.9-47176.6173167.7169.148.50111.5I110 A137 I143 L144 D145 L206I110-K141 HydrophobicContact CD1-CG 4.26Å; I110-K141 HydrophobicContact CG2-CD 3.84Å; A137-K141 PolarHBondContact O-N 3.17Å; K141-I143 PolarHBondContact O-N 3.31Å; K141-L144 CarbonylContact O-C 3.52Å; K141-L144 PolarHBondContact O-N 2.97Å; K141-D145 VanDerWaalsContact CG-OD2 3.27Å; K141-D145 WeakPolarHBondContact CG-OD2 3.44Å; K141-D145 IonicContact NZ-OD1 3.78Å; K141-D145 IonicContact NZ-OD2 2.81Å; K141-D145 PolarHBondContact NZ-OD2 3.24Å; K141-D145 WeakPolarHBondContact O-CB 3.36Å; K141-D145 VanDerWaalsContact O-CG 3.26Å; K141-D145 PolarHBondContact O-N 3.12Å; K141-L206 HydrophobicContact CD-CB 4.3Å; K141-L206 HydrophobicContact CD-CD2 3.74Å
142W98.7Very high97.9Very high17 Ų1731.5 Ų31.56%0.06416%0.161CC..Hα-helixtrans-59.1-47179.8-170.498.4000112.3W43 Y97 I100 T107 I110 T138 K139 V140 L144 D145 H146W43-W142 HydrophobicContact CH2-CH2 4.14Å; W43-W142 AromaticContact CH2-CZ2 3.49Å; W43-W142 HydrophobicContact CH2-CZ2 3.49Å; W43-W142 VanDerWaalsContact CH2-CZ2 3.49Å; W43-W142 HydrophobicContact CZ2-CZ2 4.36Å; W43-W142 HydrophobicContact CZ3-CH2 4Å; W43-W142 AromaticContact CZ3-CZ2 3.81Å; W43-W142 HydrophobicContact CZ3-CZ2 3.81Å; Y97-W142 HydrophobicContact CD1-CZ3 4.16Å; Y97-W142 HydrophobicContact CE1-CE3 4.44Å; Y97-W142 HydrophobicContact CE1-CH2 4.17Å; Y97-W142 AromaticContact CE1-CZ3 3.54Å; Y97-W142 HydrophobicContact CE1-CZ3 3.54Å; Y97-W142 HydrophobicContact CE2-CH2 4.47Å; Y97-W142 HydrophobicContact CE2-CZ3 4.24Å; Y97-W142 AromaticContact CZ-CH2 3.8Å; Y97-W142 AromaticContact CZ-CZ3 3.57Å; Y97-W142 WeakPolarHBondContact OH-CH2 3.49Å; I100-W142 HydrophobicContact CD1-CD2 4.29Å; I100-W142 HydrophobicContact CD1-CE3 3.66Å; I100-W142 HydrophobicContact CD1-CZ3 4.29Å; T107-W142 HydrophobicContact CG2-CB 3.6Å; T107-W142 HydrophobicContact CG2-CG 3.87Å; I110-W142 HydrophobicContact CD1-CB 3.85Å; I110-W142 HydrophobicContact CD1-CG 4.35Å; T138-W142 VanDerWaalsContact O-CB 3.29Å; T138-W142 WeakPolarHBondContact O-CB 3.48Å; T138-W142 PolarHBondContact O-N 3.24Å; K139-W142 PolarHBondContact O-N 3.11Å; V140-W142 VanDerWaalsContact C-N 3.28Å; V140-W142 PolarHBondContact O-N 2.85Å; W142-L144 VanDerWaalsContact C-N 3.34Å; W142-L144 PolarHBondContact O-N 3.01Å; W142-D145 PolarHBondContact O-N 3.47Å; W142-H146 AromaticContact CD1-CE1 3.56Å; W142-H146 AromaticContact CD1-ND1 3.79Å; W142-H146 HydrophobicContact CD2-CB 4.48Å; W142-H146 AromaticContact CD2-ND1 3.59Å; W142-H146 AromaticContact CE2-CD2 3.99Å; W142-H146 AromaticContact CE2-CE1 3.62Å; W142-H146 AromaticContact CE2-CG 3.75Å; W142-H146 AromaticContact CE2-ND1 3.5Å; W142-H146 AromaticContact CE2-NE2 3.9Å; W142-H146 HydrophobicContact CE3-CB 4.26Å; W142-H146 AromaticContact CG-ND1 3.76Å; W142-H146 HydrophobicContact CH2-CB 4Å; W142-H146 HydrophobicContact CZ2-CB 4.21Å; W142-H146 AromaticContact CZ2-CD2 3.79Å; W142-H146 AromaticContact CZ2-CG 3.74Å; W142-H146 AromaticContact CZ2-ND1 3.99Å; W142-H146 HydrophobicContact CZ3-CB 4.02Å; W142-H146 AromaticContact NE1-CE1 3.31Å; W142-H146 PolarHBondContact NE1-CE1 3.01Å; W142-H146 VanDerWaalsContact NE1-CE1 3.31Å; W142-H146 AromaticContact NE1-ND1 3.65Å; W142-H146 AromaticContact NE1-NE2 3.71Å; W142-H146 WeakPolarHBondContact O-CB 3.3Å; W142-H146 PolarHBondContact O-N 3.27Å; W142-H146 PolarHBondContact O-ND1 2.72Å
143I98.7Very high98.1Very high1 Ų134.5 Ų34.51%0.00517%0.172CC..Hα-helixtrans-61.6-45177.7-66.2169.7000110.1T85 I87 I96 Y97 I100 K139 V140 K141 D145 H146 V147T85-I143 HydrophobicContact CG2-CD1 4.16Å; I87-I143 HydrophobicContact CB-CG2 4.43Å; I87-I143 HydrophobicContact CD1-CB 3.96Å; I87-I143 HydrophobicContact CD1-CD1 4.21Å; I87-I143 HydrophobicContact CD1-CG2 3.83Å; I87-I143 HydrophobicContact CG1-CD1 4.18Å; I87-I143 HydrophobicContact CG1-CG2 4.43Å; I96-I143 HydrophobicContact CD1-CG2 3.74Å; I96-I143 HydrophobicContact CG1-CG2 4.19Å; Y97-I143 HydrophobicContact CD1-CD1 4.45Å; Y97-I143 HydrophobicContact CD1-CG1 4.12Å; I100-I143 HydrophobicContact CD1-CD1 3.82Å; I100-I143 HydrophobicContact CD1-CG1 3.51Å; I100-I143 HydrophobicContact CG1-CD1 4.2Å; I100-I143 HydrophobicContact CG1-CG1 4.31Å; K139-I143 WeakPolarHBondContact O-CG1 3.47Å; K139-I143 PolarHBondContact O-N 3.36Å; V140-I143 PolarHBondContact O-N 2.67Å; K141-I143 PolarHBondContact O-N 3.31Å; I143-D145 PolarHBondContact O-N 3.42Å; I143-H146 PolarHBondContact O-N 3.28Å; I143-V147 HydrophobicContact CG2-CB 4.47Å; I143-V147 HydrophobicContact CG2-CG2 3.81Å; I143-V147 WeakPolarHBondContact O-CB 3.45Å; I143-V147 PolarHBondContact O-N 2.76Å
144L98.6Very high98.3Very high6 Ų634.5 Ų34.53%0.03117%0.172CC..Hα-helixtrans-68.6-19.9179.4-64.7-178.7000113.8I87 V140 K141 W142 S150 R151 A154 I212I87-L144 HydrophobicContact CD1-CD2 4.18Å; I87-L144 HydrophobicContact CD1-CG 4.27Å; V140-L144 HydrophobicContact CG1-CD1 3.97Å; V140-L144 HydrophobicContact CG1-CG 4.4Å; V140-L144 WeakPolarHBondContact O-CG 2.93Å; V140-L144 PolarHBondContact O-N 3.4Å; K141-L144 CarbonylContact O-C 3.52Å; K141-L144 PolarHBondContact O-N 2.97Å; W142-L144 VanDerWaalsContact C-N 3.34Å; W142-L144 PolarHBondContact O-N 3.01Å; L144-S150 WeakPolarHBondContact CA-OG 3.39Å; L144-R151 PolarHBondContact O-NE 3.1Å; L144-R151 PolarHBondContact O-NH2 3.4Å; L144-A154 HydrophobicContact CD2-CB 4.1Å; L144-I212 HydrophobicContact CD1-CD1 4.49Å
145D98.1Very high98.4Very high74 Ų7439.5 Ų39.540%0.39619%0.191SC..Hα-helixtrans-86.3-30.7174.7-74.9-27000111.9K141 W142 I143 R151K141-D145 VanDerWaalsContact CG-OD2 3.27Å; K141-D145 WeakPolarHBondContact CG-OD2 3.44Å; K141-D145 IonicContact NZ-OD1 3.78Å; K141-D145 IonicContact NZ-OD2 2.81Å; K141-D145 PolarHBondContact NZ-OD2 3.24Å; K141-D145 WeakPolarHBondContact O-CB 3.36Å; K141-D145 VanDerWaalsContact O-CG 3.26Å; K141-D145 PolarHBondContact O-N 3.12Å; W142-D145 PolarHBondContact O-N 3.47Å; I143-D145 PolarHBondContact O-N 3.42Å; D145-R151 IonicContact OD1-CZ 2.72Å; D145-R151 IonicContact OD1-NH1 3.93Å; D145-R151 IonicContact OD1-NH2 2.95Å; D145-R151 PolarHBondContact OD1-NH2 3.47Å
146H98Very high98.4Very high115 Ų11544.1 Ų44.153%0.53222%0.216SC..Hα-helixtrans-108.6-23.9-169.1-67.678.4000115W142 I143W142-H146 AromaticContact CD1-CE1 3.56Å; W142-H146 AromaticContact CD1-ND1 3.79Å; W142-H146 HydrophobicContact CD2-CB 4.48Å; W142-H146 AromaticContact CD2-ND1 3.59Å; W142-H146 AromaticContact CE2-CD2 3.99Å; W142-H146 AromaticContact CE2-CE1 3.62Å; W142-H146 AromaticContact CE2-CG 3.75Å; W142-H146 AromaticContact CE2-ND1 3.5Å; W142-H146 AromaticContact CE2-NE2 3.9Å; W142-H146 HydrophobicContact CE3-CB 4.26Å; W142-H146 AromaticContact CG-ND1 3.76Å; W142-H146 HydrophobicContact CH2-CB 4Å; W142-H146 HydrophobicContact CZ2-CB 4.21Å; W142-H146 AromaticContact CZ2-CD2 3.79Å; W142-H146 AromaticContact CZ2-CG 3.74Å; W142-H146 AromaticContact CZ2-ND1 3.99Å; W142-H146 HydrophobicContact CZ3-CB 4.02Å; W142-H146 AromaticContact NE1-CE1 3.31Å; W142-H146 PolarHBondContact NE1-CE1 3.01Å; W142-H146 VanDerWaalsContact NE1-CE1 3.31Å; W142-H146 AromaticContact NE1-ND1 3.65Å; W142-H146 AromaticContact NE1-NE2 3.71Å; W142-H146 WeakPolarHBondContact O-CB 3.3Å; W142-H146 PolarHBondContact O-N 3.27Å; W142-H146 PolarHBondContact O-ND1 2.72Å; I143-H146 PolarHBondContact O-N 3.28Å
147V98.3Very high98.3Very high29 Ų2945.4 Ų45.418%0.17623%0.228CC..SBendtrans-87.9115.5174.7-178.20000109I96 Y97 I143 G149 S150I96-V147 HydrophobicContact CB-CG1 4.43Å; I96-V147 HydrophobicContact CD1-CB 4.28Å; I96-V147 HydrophobicContact CD1-CG1 4.09Å; I96-V147 HydrophobicContact CD1-CG2 4.46Å; Y97-V147 HydrophobicContact CD2-CG2 4.08Å; Y97-V147 HydrophobicContact CG-CG2 4.24Å; I143-V147 HydrophobicContact CG2-CB 4.47Å; I143-V147 HydrophobicContact CG2-CG2 3.81Å; I143-V147 WeakPolarHBondContact O-CB 3.45Å; I143-V147 PolarHBondContact O-N 2.76Å; V147-G149 PolarHBondContact O-N 3.49Å; V147-S150 VanDerWaalsContact O-CB 3.22Å; V147-S150 WeakPolarHBondContact O-CB 3.46Å; V147-S150 PolarHBondContact O-N 3.46Å; V147-S150 VanDerWaalsContact O-N 3.12Å; V147-S150 PolarHBondContact O-OG 3.39Å
148E97.9Very high98.3Very high188 Ų18849.1 Ų49.188%0.87925%0.246SC*.THydrogen-bonded Turntrans-54.1130.2-175-171.6177.3179.500112.4S150E148-S150 PolarHBondContact O-N 2.89Å
149G97.8Very high98.3Very high45 Ų4549.1 Ų49.146%0.46425%0.246SC..THydrogen-bonded Turntrans71.1-8.4178.700000115.7V147 R151 E152 R153V147-G149 PolarHBondContact O-N 3.49Å; G149-R151 VanDerWaalsContact C-N 3.28Å; G149-R151 PolarHBondContact O-N 2.96Å; G149-E152 PolarHBondContact O-N 2.72Å; G149-R153 VanDerWaalsContact O-CG 3.32Å; G149-R153 WeakPolarHBondContact O-CG 3.42Å; G149-R153 PolarHBondContact O-N 3.07Å
150S98.4Very high98.3Very high1 Ų149.5 Ų49.51%0.00725%0.248CC..Hα-helixtrans-57.4-37.5-173.860.30000113.6L144 V147 E148 R153 A154 L159L144-S150 WeakPolarHBondContact CA-OG 3.39Å; V147-S150 VanDerWaalsContact O-CB 3.22Å; V147-S150 WeakPolarHBondContact O-CB 3.46Å; V147-S150 PolarHBondContact O-N 3.46Å; V147-S150 VanDerWaalsContact O-N 3.12Å; V147-S150 PolarHBondContact O-OG 3.39Å; E148-S150 PolarHBondContact O-N 2.89Å; S150-R153 PolarHBondContact O-N 3.38Å; S150-A154 WeakPolarHBondContact O-CB 3.33Å; S150-A154 PolarHBondContact O-N 2.87Å; S150-L159 VanDerWaalsContact O-CD1 3.24Å; S150-L159 WeakPolarHBondContact O-CD1 3.49Å
151R98Very high98.3Very high35 Ų3549.5 Ų49.513%0.13225%0.248CC..Hα-helixtrans-64.2-42.9179.9-167.1164.6-55.1-129.3-11.6113.8L144 D145 G149 A154 R155 D207L144-R151 PolarHBondContact O-NE 3.1Å; L144-R151 PolarHBondContact O-NH2 3.4Å; D145-R151 IonicContact OD1-CZ 2.72Å; D145-R151 IonicContact OD1-NH1 3.93Å; D145-R151 IonicContact OD1-NH2 2.95Å; D145-R151 PolarHBondContact OD1-NH2 3.47Å; G149-R151 VanDerWaalsContact C-N 3.28Å; G149-R151 PolarHBondContact O-N 2.96Å; R151-A154 WeakPolarHBondContact O-CB 3.37Å; R151-A154 PolarHBondContact O-N 2.92Å; R151-R155 WeakPolarHBondContact O-CG 3.49Å; R151-R155 PolarHBondContact O-N 3.35Å; R151-R155 VanDerWaalsContact O-N 3.07Å; R151-D207 VanDerWaalsContact CD-OD2 3.28Å; R151-D207 WeakPolarHBondContact CD-OD2 3.48Å; R151-D207 IonicContact CZ-OD2 3.17Å; R151-D207 IonicContact NE-OD2 3.91Å; R151-D207 VanDerWaalsContact NH1-CB 3.34Å; R151-D207 VanDerWaalsContact NH1-CG 3.28Å; R151-D207 PolarHBondContact NH1-O 3.03Å; R151-D207 IonicContact NH1-OD2 3.09Å; R151-D207 PolarHBondContact NH1-OD2 3.34Å
152E98.1Very high98.3Very high105 Ų10547.7 Ų47.749%0.49124%0.24SC..Hα-helixtrans-68.6-41.8178.2-171.661.1-16900110.5G149 A154 R155 N156G149-E152 PolarHBondContact O-N 2.72Å; E152-A154 VanDerWaalsContact C-N 3.3Å; E152-A154 PolarHBondContact O-N 3.45Å; E152-R155 PolarHBondContact O-N 3.16Å; E152-R155 VanDerWaalsContact O-N 3.16Å; E152-R155 IonicContact OE2-NH1 2.72Å; E152-N156 VanDerWaalsContact O-CG 3.27Å; E152-N156 PolarHBondContact O-N 2.98Å; E152-N156 PolarHBondContact O-ND2 2.95Å
153R98.3Very high98.3Very high67 Ų6746.9 Ų46.925%0.25324%0.237SC..Hα-helixtrans-59.6-40174.1-62.8175.764.8-164.81.9112.2E89 G149 S150 N156 G157 E158 L159E89-R153 IonicContact OE1-CZ 3.3Å; E89-R153 IonicContact OE1-NH1 2.74Å; E89-R153 PolarHBondContact OE1-NH1 2.71Å; E89-R153 IonicContact OE1-NH2 3.82Å; E89-R153 PolarHBondContact OE1-NH2 3.11Å; G149-R153 VanDerWaalsContact O-CG 3.32Å; G149-R153 WeakPolarHBondContact O-CG 3.42Å; G149-R153 PolarHBondContact O-N 3.07Å; S150-R153 PolarHBondContact O-N 3.38Å; R153-N156 PolarHBondContact O-N 3.38Å; R153-G157 PolarHBondContact O-N 3.44Å; R153-E158 HydrophobicContact CB-CB 4.21Å; R153-E158 WeakPolarHBondContact CB-OE2 3.21Å; R153-E158 VanDerWaalsContact CG-OE2 3.28Å; R153-E158 WeakPolarHBondContact CG-OE2 3.42Å; R153-E158 IonicContact NE-OE2 3.07Å; R153-E158 PolarHBondContact NE-OE2 3.08Å; R153-E158 WeakPolarHBondContact O-CB 3.3Å; R153-E158 PolarHBondContact O-N 2.82Å; R153-L159 HydrophobicContact CB-CD1 4.03Å; R153-L159 HydrophobicContact CB-CD2 4.49Å; R153-L159 HydrophobicContact CB-CG 3.94Å
154A98.4Very high98.3Very high0 Ų046.9 Ų46.90%024%0.237CC..Hα-helixtrans-61.5-46173.600000112.1L144 S150 R151 E152 N156 G157 L159 P209 I212L144-A154 HydrophobicContact CD2-CB 4.1Å; S150-A154 WeakPolarHBondContact O-CB 3.33Å; S150-A154 PolarHBondContact O-N 2.87Å; R151-A154 WeakPolarHBondContact O-CB 3.37Å; R151-A154 PolarHBondContact O-N 2.92Å; E152-A154 VanDerWaalsContact C-N 3.3Å; E152-A154 PolarHBondContact O-N 3.45Å; A154-N156 VanDerWaalsContact C-N 3.26Å; A154-N156 PolarHBondContact O-N 3.31Å; A154-G157 PolarHBondContact O-N 3.02Å; A154-L159 HydrophobicContact CB-CB 4.37Å; A154-L159 HydrophobicContact CB-CD1 4.22Å; A154-P209 HydrophobicContact CB-CB 4.41Å; A154-P209 HydrophobicContact CB-CG 3.9Å; A154-I212 HydrophobicContact CB-CG2 3.57Å
155R97.9Very high98.3Very high108 Ų10846.6 Ų46.641%0.40824%0.235SC..Hα-helixtrans-63.9-30175.7-69.7177.1-178.3143.8-0.3113R151 E152 G157 D207 P209R151-R155 WeakPolarHBondContact O-CG 3.49Å; R151-R155 PolarHBondContact O-N 3.35Å; R151-R155 VanDerWaalsContact O-N 3.07Å; E152-R155 PolarHBondContact O-N 3.16Å; E152-R155 VanDerWaalsContact O-N 3.16Å; E152-R155 IonicContact OE2-NH1 2.72Å; R155-G157 PolarHBondContact O-N 3.38Å; R155-D207 IonicContact CZ-OD1 3.71Å; R155-D207 IonicContact NH2-OD1 3.33Å; R155-D207 PolarHBondContact NH2-OD1 3.42Å; R155-D207 IonicContact NH2-OD2 2.88Å; R155-D207 PolarHBondContact NH2-OD2 2.84Å; R155-P209 HydrophobicContact CG-CB 4Å; R155-P209 HydrophobicContact CG-CG 3.55Å
156N98Very high98.4Very high97 Ų9743 Ų4352%0.51922%0.216SC..THydrogen-bonded Turntrans-77.2-2.5174.2-67.4-20000113.7E152 R153 A154 E158E152-N156 VanDerWaalsContact O-CG 3.27Å; E152-N156 PolarHBondContact O-N 2.98Å; E152-N156 PolarHBondContact O-ND2 2.95Å; R153-N156 PolarHBondContact O-N 3.38Å; A154-N156 VanDerWaalsContact C-N 3.26Å; A154-N156 PolarHBondContact O-N 3.31Å; N156-E158 VanDerWaalsContact C-N 3.28Å; N156-E158 HydrophobicContact CB-CG 3.91Å; N156-E158 WeakPolarHBondContact CB-OE1 3.37Å; N156-E158 PolarHBondContact ND2-OE1 3.28Å; N156-E158 VanDerWaalsContact ND2-OE1 3.15Å; N156-E158 PolarHBondContact O-N 3.18Å
157G97.5Very high98.4Very high26 Ų2637.6 Ų37.627%0.26819%0.191SC..THydrogen-bonded Turntrans72.419.4-177.300000114.1R153 A154 R155R153-G157 PolarHBondContact O-N 3.44Å; A154-G157 PolarHBondContact O-N 3.02Å; R155-G157 PolarHBondContact O-N 3.38Å
158E98.5Very high98.5Very high78 Ų7836.2 Ų36.236%0.36418%0.183SC..  trans-82.8-21.1178.6-58.9169.2-149.400112.5K90 R153 N156K90-E158 PolarHBondContact N-O 3.15Å; R153-E158 HydrophobicContact CB-CB 4.21Å; R153-E158 WeakPolarHBondContact CB-OE2 3.21Å; R153-E158 VanDerWaalsContact CG-OE2 3.28Å; R153-E158 WeakPolarHBondContact CG-OE2 3.42Å; R153-E158 IonicContact NE-OE2 3.07Å; R153-E158 PolarHBondContact NE-OE2 3.08Å; R153-E158 WeakPolarHBondContact O-CB 3.3Å; R153-E158 PolarHBondContact O-N 2.82Å; N156-E158 VanDerWaalsContact C-N 3.28Å; N156-E158 HydrophobicContact CB-CG 3.91Å; N156-E158 WeakPolarHBondContact CB-OE1 3.37Å; N156-E158 PolarHBondContact ND2-OE1 3.28Å; N156-E158 VanDerWaalsContact ND2-OE1 3.15Å; N156-E158 PolarHBondContact O-N 3.18Å
159L98.8Very high98.5Very high0 Ų027.2 Ų27.20%014%0.141CC..EExtended strand (participates in β ladder)trans-113.7151.7-178-56.1-175.7000111.5I87 W88 E89 I96 S150 R153 A154 I212I87-L159 HydrophobicContact CG2-CB 4.1Å; I87-L159 HydrophobicContact CG2-CD1 4.12Å; W88-L159 CarbonylContact O-C 3.55Å; W88-L159 VanDerWaalsContact O-CA 3.31Å; W88-L159 WeakPolarHBondContact O-CA 3.33Å; E89-L159 HydrophobicContact CG-CD2 4.06Å; I96-L159 HydrophobicContact CD1-CD1 3.85Å; I96-L159 HydrophobicContact CG2-CD2 3.74Å; S150-L159 VanDerWaalsContact O-CD1 3.24Å; S150-L159 WeakPolarHBondContact O-CD1 3.49Å; R153-L159 HydrophobicContact CB-CD1 4.03Å; R153-L159 HydrophobicContact CB-CD2 4.49Å; R153-L159 HydrophobicContact CB-CG 3.94Å; A154-L159 HydrophobicContact CB-CB 4.37Å; A154-L159 HydrophobicContact CB-CD1 4.22Å; L159-I212 HydrophobicContact CB-CG2 4.48Å; L159-I212 WeakPolarHBondContact O-CG2 3.44Å
160L98.9Very high98.5Very high8 Ų826 Ų264%0.04212%0.122CC..EExtended strand (participates in β ladder)trans-125.3148172.2-60.1-179.8000109.8I87 W88 K90 W170 H178I87-L160 VanDerWaalsContact CA-O 3.26Å; I87-L160 WeakPolarHBondContact CA-O 3.44Å; I87-L160 WeakPolarHBondContact CG2-O 3.43Å; W88-L160 HydrophobicContact CD2-CB 4.17Å; W88-L160 HydrophobicContact CH2-CB 4.22Å; W88-L160 HydrophobicContact CZ2-CB 3.63Å; W88-L160 HydrophobicContact CZ2-CD1 4.03Å; W88-L160 HydrophobicContact CZ2-CG 4.5Å; W88-L160 PolarHBondContact N-O 2.91Å; W88-L160 PolarHBondContact O-N 2.61Å; K90-L160 HydrophobicContact CB-CD1 4.24Å; K90-L160 HydrophobicContact CB-CG 4.1Å; K90-L160 HydrophobicContact CD-CD2 4.36Å; K90-L160 HydrophobicContact CG-CD1 4.04Å; K90-L160 HydrophobicContact CG-CG 4.3Å; L160-W170 HydrophobicContact CD1-CD2 4.36Å; L160-W170 HydrophobicContact CD1-CE3 4.26Å; L160-W170 HydrophobicContact CD1-CH2 3.75Å; L160-W170 HydrophobicContact CD1-CZ2 3.86Å; L160-W170 HydrophobicContact CD1-CZ3 3.97Å; L160-H178 HydrophobicContact CD1-CB 4.48Å
161F98.9Very high98.6Very high1 Ų127.8 Ų27.80%0.00413%0.13CC..EExtended strand (participates in β ladder)trans-107.7150.3171.1156.4-102.8000109.9T85 V86 V140 T163 H178 T188 M190 W198 I212 L213T85-F161 HydrophobicContact CG2-CD2 3.94Å; T85-F161 HydrophobicContact CG2-CE2 3.73Å; V86-F161 WeakPolarHBondContact O-CA 3.28Å; V140-F161 HydrophobicContact CG2-CD2 3.36Å; V140-F161 HydrophobicContact CG2-CE2 3.39Å; V140-F161 HydrophobicContact CG2-CG 4.1Å; V140-F161 HydrophobicContact CG2-CZ 4.15Å; F161-T163 HydrophobicContact CZ-CG2 4.46Å; F161-H178 PolarHBondContact O-NE2 3.45Å; F161-T188 HydrophobicContact CE1-CG2 4.24Å; F161-T188 HydrophobicContact CZ-CG2 4.04Å; F161-M190 HydrophobicContact CD1-CE 4.09Å; F161-M190 HydrophobicContact CE1-CE 3.45Å; F161-M190 VanDerWaalsContact CE1-CE 3.45Å; F161-M190 HydrophobicContact CE2-CE 4.29Å; F161-M190 HydrophobicContact CZ-CE 3.57Å; F161-W198 HydrophobicContact CE1-CH2 4.45Å; F161-I212 HydrophobicContact CB-CB 4.09Å; F161-I212 HydrophobicContact CB-CD1 3.74Å; F161-I212 HydrophobicContact CB-CG1 3.68Å; F161-I212 PolarHBondContact N-O 3.16Å; F161-L213 HydrophobicContact CD1-CD2 3.87Å; F161-L213 HydrophobicContact CE1-CD2 4.36Å
162G98.9Very high98.6Very high0 Ų026.2 Ų26.20%012%0.124CC..EExtended strand (participates in β ladder)trans-161.7150168.200000111.9V86 W88V86-G162 PolarHBondContact N-O 3.07Å; V86-G162 PolarHBondContact O-N 2.67Å; W88-G162 VanDerWaalsContact CZ3-N 3.3Å
163T98.9Very high98.6Very high1 Ų121.5 Ų21.51%0.00610%0.103CC..  trans-68.9174.9151.242.80000109.5T84 F161 D165 T166 W167 T188T84-T163 WeakPolarHBondContact O-CA 3.32Å; F161-T163 HydrophobicContact CZ-CG2 4.46Å; T163-D165 VanDerWaalsContact C-N 3.34Å; T163-D165 WeakPolarHBondContact CB-OD1 3.44Å; T163-D165 PolarHBondContact O-N 3.29Å; T163-D165 PolarHBondContact OG1-OD1 3.04Å; T163-T166 WeakPolarHBondContact O-CB 3.45Å; T163-T166 PolarHBondContact O-N 2.74Å; T163-W167 PolarHBondContact O-N 3.11Å; T163-T188 HydrophobicContact CG2-CG2 4.33Å
164I98.9Very high98.6Very high0 Ų019.9 Ų19.90%011%0.107CC..Hα-helixtrans-62.8-36.8-171.6-67.1-58.4000112.9Q10 I51 N80 Q81 T84 V86 T166 W167 L168Q10-I164 HydrophobicContact CB-CG2 3.88Å; Q10-I164 HydrophobicContact CG-CG2 3.74Å; I51-I164 HydrophobicContact CD1-CD1 4.06Å; N80-I164 HydrophobicContact CB-CB 3.73Å; N80-I164 HydrophobicContact CB-CG2 3.56Å; Q81-I164 HydrophobicContact CG-CG1 3.98Å; T84-I164 HydrophobicContact CG2-CD1 3.78Å; T84-I164 HydrophobicContact CG2-CG1 3.86Å; V86-I164 HydrophobicContact CG2-CD1 3.84Å; I164-T166 PolarHBondContact O-N 3.13Å; I164-W167 WeakPolarHBondContact O-CB 3.48Å; I164-W167 PolarHBondContact O-N 3.44Å; I164-L168 HydrophobicContact CG2-CD1 3.97Å; I164-L168 HydrophobicContact CG2-CG 4.1Å; I164-L168 VanDerWaalsContact O-CG 3.26Å; I164-L168 WeakPolarHBondContact O-CG 3.34Å; I164-L168 PolarHBondContact O-N 3.35Å
165D98.9Very high98.5Very high0 Ų021 Ų210%012%0.118CC..Hα-helixtrans-52.6-52171.854.1-50.1000111.8N80 T163 W167 L168 V169 S180 N184 M241N80-D165 WeakPolarHBondContact OD1-CB 3.46Å; T163-D165 VanDerWaalsContact C-N 3.34Å; T163-D165 WeakPolarHBondContact CB-OD1 3.44Å; T163-D165 PolarHBondContact O-N 3.29Å; T163-D165 PolarHBondContact OG1-OD1 3.04Å; D165-W167 VanDerWaalsContact C-N 3.33Å; D165-W167 PolarHBondContact O-N 2.92Å; D165-L168 PolarHBondContact O-N 2.88Å; D165-L168 VanDerWaalsContact O-N 3.16Å; D165-V169 WeakPolarHBondContact O-CG2 3.22Å; D165-V169 PolarHBondContact O-N 2.85Å; D165-S180 VanDerWaalsContact OD2-CA 3.32Å; D165-S180 WeakPolarHBondContact OD2-CA 3.43Å; D165-S180 WeakPolarHBondContact OD2-CB 3.17Å; D165-S180 PolarHBondContact OD2-OG 3.12Å; D165-N184 VanDerWaalsContact CG-CG 3.43Å; D165-N184 PolarHBondContact OD1-ND2 2.88Å; D165-N184 PolarHBondContact OD2-ND2 3.3Å; D165-M241 HydrophobicContact CB-SD 4.14Å
166T98.9Very high98.5Very high0 Ų023.8 Ų23.80%014%0.136CC..Hα-helixtrans-60.2-44.3178.4-54.70000111.5W88 T163 I164 L168 V169 W170 H178 V179 S180 P214W88-T166 HydrophobicContact CH2-CG2 3.86Å; T163-T166 WeakPolarHBondContact O-CB 3.45Å; T163-T166 PolarHBondContact O-N 2.74Å; I164-T166 PolarHBondContact O-N 3.13Å; T166-L168 PolarHBondContact O-N 2.95Å; T166-V169 PolarHBondContact O-N 2.83Å; T166-W170 VanDerWaalsContact O-CB 3.28Å; T166-W170 WeakPolarHBondContact O-CB 3.26Å; T166-W170 PolarHBondContact O-N 2.95Å; T166-H178 WeakPolarHBondContact CG2-CD2 3.38Å; T166-V179 WeakPolarHBondContact CA-O 3.4Å; T166-V179 VanDerWaalsContact CB-O 3.27Å; T166-V179 WeakPolarHBondContact CB-O 3.42Å; T166-V179 WeakPolarHBondContact CG2-O 3.37Å; T166-V179 PolarHBondContact OG1-O 2.98Å; T166-S180 WeakPolarHBondContact OG1-CB 3.43Å; T166-P214 HydrophobicContact CG2-CB 3.85Å; T166-P214 HydrophobicContact CG2-CG 4.09Å
167W98.9Very high98.6Very high0 Ų020.6 Ų20.60%012%0.12CC..Hα-helixtrans-58.5-47.4175.5171.1-117.4000111.3A48 V86 W88 G93 P95 T163 I164 D165 W170 K171A48-W167 HydrophobicContact CB-CZ2 4.05Å; A48-W167 PolarHBondContact O-NE1 3.47Å; V86-W167 HydrophobicContact CG1-CD2 4.48Å; V86-W167 HydrophobicContact CG1-CE3 4.4Å; V86-W167 HydrophobicContact CG2-CB 4.39Å; W88-W167 HydrophobicContact CB-CZ3 4.06Å; W88-W167 AromaticContact CD2-CE3 3.86Å; W88-W167 HydrophobicContact CD2-CE3 3.86Å; W88-W167 AromaticContact CD2-CZ3 3.93Å; W88-W167 HydrophobicContact CD2-CZ3 3.93Å; W88-W167 AromaticContact CE3-CE3 3.86Å; W88-W167 HydrophobicContact CE3-CE3 3.86Å; W88-W167 HydrophobicContact CE3-CZ3 4.28Å; W88-W167 HydrophobicContact CG-CE3 4.25Å; W88-W167 AromaticContact CG-CZ3 3.81Å; W88-W167 HydrophobicContact CG-CZ3 3.81Å; W88-W167 HydrophobicContact CZ3-CE3 4.28Å; G93-W167 WeakPolarHBondContact O-CH2 3.48Å; P95-W167 HydrophobicContact CG-CH2 3.96Å; P95-W167 HydrophobicContact CG-CZ2 4.35Å; T163-W167 PolarHBondContact O-N 3.11Å; I164-W167 WeakPolarHBondContact O-CB 3.48Å; I164-W167 PolarHBondContact O-N 3.44Å; D165-W167 VanDerWaalsContact C-N 3.33Å; D165-W167 PolarHBondContact O-N 2.92Å; W167-W170 WeakPolarHBondContact O-CB 3.4Å; W167-W170 PolarHBondContact O-N 3.01Å; W167-K171 HydrophobicContact CD2-CD 4.38Å; W167-K171 HydrophobicContact CD2-CG 4.06Å; W167-K171 HydrophobicContact CE3-CD 4.24Å; W167-K171 HydrophobicContact CE3-CG 4.33Å; W167-K171 HydrophobicContact CH2-CD 3.59Å; W167-K171 HydrophobicContact CH2-CG 4.26Å; W167-K171 HydrophobicContact CZ2-CD 3.69Å; W167-K171 HydrophobicContact CZ2-CG 3.93Å; W167-K171 HydrophobicContact CZ3-CD 3.86Å; W167-K171 HydrophobicContact CZ3-CG 4.42Å; W167-K171 WeakPolarHBondContact O-CG 3.4Å; W167-K171 PolarHBondContact O-N 3.37Å
168L98.9Very high98.6Very high0 Ų021 Ų210%011%0.114CC..Hα-helixtrans-67-41.3-178.4-66.6-177.7000112.6I8 Q10 I51 W52 V55 I78 I164 D165 T166 W170 K171 L172I8-L168 HydrophobicContact CG2-CD1 4.36Å; Q10-L168 HydrophobicContact CB-CD1 3.86Å; Q10-L168 HydrophobicContact CG-CD1 4.18Å; I51-L168 HydrophobicContact CG2-CD2 4.37Å; W52-L168 HydrophobicContact CE3-CD2 4.19Å; V55-L168 HydrophobicContact CB-CD2 4.39Å; V55-L168 HydrophobicContact CG1-CD2 4.46Å; V55-L168 HydrophobicContact CG2-CD1 4.3Å; V55-L168 HydrophobicContact CG2-CD2 3.86Å; I78-L168 HydrophobicContact CD1-CB 4.46Å; I78-L168 HydrophobicContact CG2-CB 4.33Å; I78-L168 HydrophobicContact CG2-CD1 3.89Å; I164-L168 HydrophobicContact CG2-CD1 3.97Å; I164-L168 HydrophobicContact CG2-CG 4.1Å; I164-L168 VanDerWaalsContact O-CG 3.26Å; I164-L168 WeakPolarHBondContact O-CG 3.34Å; I164-L168 PolarHBondContact O-N 3.35Å; D165-L168 PolarHBondContact O-N 2.88Å; D165-L168 VanDerWaalsContact O-N 3.16Å; T166-L168 PolarHBondContact O-N 2.95Å; L168-W170 VanDerWaalsContact C-N 3.35Å; L168-K171 PolarHBondContact O-N 3.01Å; L168-L172 WeakPolarHBondContact O-CB 3.25Å; L168-L172 VanDerWaalsContact O-CG 3.29Å; L168-L172 WeakPolarHBondContact O-CG 3.31Å; L168-L172 PolarHBondContact O-N 3.43Å
169V98.8Very high98.6Very high0 Ų017.3 Ų17.30%010%0.097CC..Hα-helixtrans-63.3-42.9174.2176.60000110.8I78 D165 T166 K171 L172 T173 V177 V179 I238 M241I78-V169 HydrophobicContact CD1-CG2 3.7Å; D165-V169 WeakPolarHBondContact O-CG2 3.22Å; D165-V169 PolarHBondContact O-N 2.85Å; T166-V169 PolarHBondContact O-N 2.83Å; V169-K171 VanDerWaalsContact C-N 3.31Å; V169-K171 PolarHBondContact O-N 2.71Å; V169-L172 PolarHBondContact O-N 2.53Å; V169-T173 HydrophobicContact CG1-CG2 3.97Å; V169-T173 WeakPolarHBondContact O-CB 3.48Å; V169-T173 VanDerWaalsContact O-CG2 3.29Å; V169-T173 WeakPolarHBondContact O-CG2 3.26Å; V169-T173 PolarHBondContact O-N 2.89Å; V169-T173 PolarHBondContact O-OG1 3.5Å; V169-V177 HydrophobicContact CG1-CB 4.04Å; V169-V177 HydrophobicContact CG1-CG1 3.94Å; V169-V179 HydrophobicContact CB-CG1 4.31Å; V169-V179 HydrophobicContact CG1-CG1 3.78Å; V169-V179 HydrophobicContact CG2-CG1 4.47Å; V169-I238 HydrophobicContact CG1-CD1 4.41Å; V169-I238 HydrophobicContact CG2-CG2 4.26Å; V169-M241 HydrophobicContact CG2-SD 3.56Å; V169-M241 VanDerWaalsContact CG2-SD 3.56Å
170W98.8Very high98.6Very high20 Ų2017.3 Ų17.38%0.07610%0.097CC..Hα-helixtrans-56.4-46.1175.9-176.2-105000111.5W88 K90 L160 T166 W167 L168 T173 G174 G175 H178W88-W170 AromaticContact CD1-NE1 3.72Å; W88-W170 AromaticContact CE2-CD1 3.82Å; W88-W170 HydrophobicContact CZ2-CB 4.14Å; W88-W170 HydrophobicContact CZ2-CD2 4.28Å; W88-W170 AromaticContact CZ2-CG 3.93Å; W88-W170 HydrophobicContact CZ2-CG 3.93Å; W88-W170 AromaticContact NE1-CD1 3.29Å; W88-W170 VanDerWaalsContact NE1-CD1 3.29Å; W88-W170 AromaticContact NE1-CD2 3.91Å; W88-W170 AromaticContact NE1-CE2 3.51Å; W88-W170 AromaticContact NE1-CG 3.79Å; W88-W170 AromaticContact NE1-NE1 3.11Å; W88-W170 VanDerWaalsContact NE1-NE1 3.11Å; K90-W170 HydrophobicContact CG-CH2 4.38Å; K90-W170 HydrophobicContact CG-CZ2 4.45Å; L160-W170 HydrophobicContact CD1-CD2 4.36Å; L160-W170 HydrophobicContact CD1-CE3 4.26Å; L160-W170 HydrophobicContact CD1-CH2 3.75Å; L160-W170 HydrophobicContact CD1-CZ2 3.86Å; L160-W170 HydrophobicContact CD1-CZ3 3.97Å; T166-W170 VanDerWaalsContact O-CB 3.28Å; T166-W170 WeakPolarHBondContact O-CB 3.26Å; T166-W170 PolarHBondContact O-N 2.95Å; W167-W170 WeakPolarHBondContact O-CB 3.4Å; W167-W170 PolarHBondContact O-N 3.01Å; L168-W170 VanDerWaalsContact C-N 3.35Å; W170-T173 PolarHBondContact O-OG1 3.21Å; W170-G174 PolarHBondContact O-N 3.16Å; W170-G175 WeakPolarHBondContact CH2-O 3.24Å; W170-G175 VanDerWaalsContact CZ3-C 3.44Å; W170-G175 WeakPolarHBondContact CZ3-O 3.08Å; W170-G175 PolarHBondContact O-N 3.48Å; W170-H178 HydrophobicContact CE3-CB 3.82Å; W170-H178 HydrophobicContact CZ3-CB 3.82Å
171K98.6Very high98.6Very high38 Ų3817 Ų1717%0.16510%0.095CC..Hα-helixtrans-66.4-48.7176.2-61-55-76-170.50112.4W52 W167 L168 V169 T173 G174 H230W52-K171 HydrophobicContact CD2-CB 3.7Å; W52-K171 HydrophobicContact CD2-CG 3.94Å; W52-K171 HydrophobicContact CE3-CB 3.7Å; W52-K171 HydrophobicContact CE3-CG 4.18Å; W52-K171 HydrophobicContact CG-CB 4.37Å; W52-K171 HydrophobicContact CG-CG 4.09Å; W52-K171 HydrophobicContact CH2-CB 4.03Å; W52-K171 HydrophobicContact CZ2-CB 4.02Å; W52-K171 HydrophobicContact CZ3-CB 3.87Å; W167-K171 HydrophobicContact CD2-CD 4.38Å; W167-K171 HydrophobicContact CD2-CG 4.06Å; W167-K171 HydrophobicContact CE3-CD 4.24Å; W167-K171 HydrophobicContact CE3-CG 4.33Å; W167-K171 HydrophobicContact CH2-CD 3.59Å; W167-K171 HydrophobicContact CH2-CG 4.26Å; W167-K171 HydrophobicContact CZ2-CD 3.69Å; W167-K171 HydrophobicContact CZ2-CG 3.93Å; W167-K171 HydrophobicContact CZ3-CD 3.86Å; W167-K171 HydrophobicContact CZ3-CG 4.42Å; W167-K171 WeakPolarHBondContact O-CG 3.4Å; W167-K171 PolarHBondContact O-N 3.37Å; L168-K171 PolarHBondContact O-N 3.01Å; V169-K171 VanDerWaalsContact C-N 3.31Å; V169-K171 PolarHBondContact O-N 2.71Å; K171-T173 VanDerWaalsContact C-N 3.27Å; K171-T173 PolarHBondContact O-N 2.71Å; K171-G174 PolarHBondContact O-N 2.99Å; K171-G174 VanDerWaalsContact O-N 3.16Å; K171-H230 PolarHBondContact O-CD2 3.01Å; K171-H230 PolarHBondContact O-NE2 2.85Å
172L98.5Very high98.6Very high1 Ų119.2 Ų19.21%0.00510%0.104CC..Hα-helixtrans-62.6-34.2-177.2-77.3165.8000112.7I8 W52 I59 I78 L168 V169 T226 A227 I238I8-L172 HydrophobicContact CD1-CD1 4.14Å; W52-L172 HydrophobicContact CH2-CD2 3.85Å; W52-L172 HydrophobicContact CH2-CG 4.13Å; W52-L172 HydrophobicContact CZ3-CD2 4.08Å; W52-L172 HydrophobicContact CZ3-CG 4.04Å; I59-L172 HydrophobicContact CD1-CD2 4.37Å; I78-L172 HydrophobicContact CD1-CD1 3.63Å; L168-L172 WeakPolarHBondContact O-CB 3.25Å; L168-L172 VanDerWaalsContact O-CG 3.29Å; L168-L172 WeakPolarHBondContact O-CG 3.31Å; L168-L172 PolarHBondContact O-N 3.43Å; V169-L172 PolarHBondContact O-N 2.53Å; L172-T226 HydrophobicContact CB-CG2 4.47Å; L172-T226 HydrophobicContact CD2-CG2 4.28Å; L172-T226 CarbonylContact O-C 3.55Å; L172-T226 WeakPolarHBondContact O-CA 3.39Å; L172-A227 PolarHBondContact O-N 3.18Å; L172-I238 HydrophobicContact CB-CD1 3.74Å; L172-I238 HydrophobicContact CD1-CD1 4.18Å
173T98.5Very high98.6Very high7 Ų719.2 Ų19.24%0.04310%0.104CC..THydrogen-bonded Turntrans-88-1.918061.80000113.7V169 W170 K171 G175 V177 I238V169-T173 HydrophobicContact CG1-CG2 3.97Å; V169-T173 WeakPolarHBondContact O-CB 3.48Å; V169-T173 VanDerWaalsContact O-CG2 3.29Å; V169-T173 WeakPolarHBondContact O-CG2 3.26Å; V169-T173 PolarHBondContact O-N 2.89Å; V169-T173 PolarHBondContact O-OG1 3.5Å; W170-T173 PolarHBondContact O-OG1 3.21Å; K171-T173 VanDerWaalsContact C-N 3.27Å; K171-T173 PolarHBondContact O-N 2.71Å; T173-G175 VanDerWaalsContact C-N 3.31Å; T173-G175 PolarHBondContact O-N 2.97Å; T173-V177 HydrophobicContact CG2-CB 3.9Å; T173-V177 HydrophobicContact CG2-CG2 3.83Å; T173-V177 PolarHBondContact OG1-N 2.98Å; T173-I238 HydrophobicContact CG2-CD1 3.76Å
174G97.5Very high98.6Very high33 Ų3319.1 Ų19.134%0.3410%0.104SC..THydrogen-bonded Turntrans71.422.9-178.800000114.3W170 K171 Y229W170-G174 PolarHBondContact O-N 3.16Å; K171-G174 PolarHBondContact O-N 2.99Å; K171-G174 VanDerWaalsContact O-N 3.16Å; G174-Y229 WeakPolarHBondContact CA-OH 3.46Å
175G97.9Very high98.6Very high23 Ų2319.1 Ų19.124%0.23710%0.104CC..SBendtrans9114.7-179.100000115.4W170 T173W170-G175 WeakPolarHBondContact CH2-O 3.24Å; W170-G175 VanDerWaalsContact CZ3-C 3.44Å; W170-G175 WeakPolarHBondContact CZ3-O 3.08Å; W170-G175 PolarHBondContact O-N 3.48Å; T173-G175 VanDerWaalsContact C-N 3.31Å; T173-G175 PolarHBondContact O-N 2.97Å
176E97.8Very high98.6Very high167 Ų16719.1 Ų19.178%0.7810%0.104SC*.SBendtrans-90-27-179.9-66.8-67.5142.100113.1
177V98.6Very high98.6Very high30 Ų3019.1 Ų19.118%0.18210%0.104CC..  trans-127.2117.5-173-174.10000111.4V169 T173 V179V169-V177 HydrophobicContact CG1-CB 4.04Å; V169-V177 HydrophobicContact CG1-CG1 3.94Å; T173-V177 HydrophobicContact CG2-CB 3.9Å; T173-V177 HydrophobicContact CG2-CG2 3.83Å; T173-V177 PolarHBondContact OG1-N 2.98Å; V177-V179 HydrophobicContact CG1-CB 4.04Å; V177-V179 HydrophobicContact CG1-CG1 3.62Å
178H98.8Very high98.6Very high33 Ų3319.2 Ų19.215%0.15310%0.104CC..  trans-114.894.7176.6-179-137.4000110.1W88 L160 F161 T166 W170 I212 P214 E215W88-H178 AromaticContact CH2-NE2 3.95Å; W88-H178 AromaticContact CZ2-CD2 3.81Å; W88-H178 AromaticContact CZ2-NE2 4Å; L160-H178 HydrophobicContact CD1-CB 4.48Å; F161-H178 PolarHBondContact O-NE2 3.45Å; T166-H178 WeakPolarHBondContact CG2-CD2 3.38Å; W170-H178 HydrophobicContact CE3-CB 3.82Å; W170-H178 HydrophobicContact CZ3-CB 3.82Å; H178-I212 PolarHBondContact CE1-O 3.18Å; H178-I212 VanDerWaalsContact CE1-O 3.25Å; H178-P214 VanDerWaalsContact CE1-CA 3.41Å; H178-P214 WeakPolarHBondContact CE1-CA 3.47Å; H178-P214 VanDerWaalsContact CE1-N 3.33Å; H178-E215 PolarHBondContact O-N 2.6Å
179V98.9Very high98.6Very high1 Ų119.2 Ų19.21%0.00610%0.104CC..EExtended strand (participates in β ladder)trans-143.9152.2-167.368.40000111.8T166 V169 V177 E215 K217 M241T166-V179 WeakPolarHBondContact CA-O 3.4Å; T166-V179 VanDerWaalsContact CB-O 3.27Å; T166-V179 WeakPolarHBondContact CB-O 3.42Å; T166-V179 WeakPolarHBondContact CG2-O 3.37Å; T166-V179 PolarHBondContact OG1-O 2.98Å; V169-V179 HydrophobicContact CB-CG1 4.31Å; V169-V179 HydrophobicContact CG1-CG1 3.78Å; V169-V179 HydrophobicContact CG2-CG1 4.47Å; V177-V179 HydrophobicContact CG1-CB 4.04Å; V177-V179 HydrophobicContact CG1-CG1 3.62Å; V179-E215 CarbonylContact C-O 3.57Å; V179-E215 VanDerWaalsContact CA-O 3.28Å; V179-E215 WeakPolarHBondContact CA-O 3.46Å; V179-E215 HydrophobicContact CG2-CB 4.48Å; V179-E215 WeakPolarHBondContact CG2-O 3.25Å; V179-K217 HydrophobicContact CG2-CB 4.02Å; V179-K217 HydrophobicContact CG2-CD 3.69Å; V179-K217 HydrophobicContact CG2-CG 3.62Å; V179-M241 HydrophobicContact CG1-CE 3.82Å; V179-M241 HydrophobicContact CG2-CE 4.2Å
180S98.9Very high98.6Very high1 Ų119.2 Ų19.21%0.00710%0.104CC..EExtended strand (participates in β ladder)trans-132.9162.8166.6-167.40000109.8D165 T166 N184 E215 V216 K217D165-S180 VanDerWaalsContact OD2-CA 3.32Å; D165-S180 WeakPolarHBondContact OD2-CA 3.43Å; D165-S180 WeakPolarHBondContact OD2-CB 3.17Å; D165-S180 PolarHBondContact OD2-OG 3.12Å; T166-S180 WeakPolarHBondContact OG1-CB 3.43Å; S180-N184 WeakPolarHBondContact OG-CB 3.26Å; S180-E215 PolarHBondContact N-O 3.23Å; S180-V216 CarbonylContact O-C 3.58Å; S180-V216 WeakPolarHBondContact O-CA 3.2Å; S180-K217 PolarHBondContact O-N 3.35Å
181D98.9Very high98.6Very high0 Ų018.4 Ų18.40%010%0.101CC..EExtended strand (participates in β ladder)trans-93.7165.9171.879.9-79.1000112.3T183 N184 A185 K217 N219 M241D181-T183 PolarHBondContact O-N 2.96Å; D181-T183 WeakPolarHBondContact OD2-CA 3.25Å; D181-T183 VanDerWaalsContact OD2-CB 3.23Å; D181-T183 WeakPolarHBondContact OD2-CB 3.25Å; D181-T183 PolarHBondContact OD2-N 3.41Å; D181-T183 PolarHBondContact OD2-OG1 3.47Å; D181-N184 PolarHBondContact O-N 2.82Å; D181-N184 PolarHBondContact OD1-ND2 3.39Å; D181-A185 VanDerWaalsContact O-CB 3.31Å; D181-A185 WeakPolarHBondContact O-CB 3.36Å; D181-A185 PolarHBondContact O-N 3.2Å; D181-K217 CarbonylContact C-O 3.55Å; D181-K217 WeakPolarHBondContact CA-O 3.46Å; D181-N219 PolarHBondContact OD2-ND2 3.46Å; D181-N219 PolarHBondContact OD2-OD1 3.33Å; D181-M241 HydrophobicContact CB-CB 3.78Å; D181-M241 HydrophobicContact CB-CE 4.33Å
182Y98.9Very high98.6Very high48 Ų4817.1 Ų17.119%0.18810%0.096CC..Hα-helixtrans-55.6-35.5-180-68-55.3000114S186 Y191 L196 V216 K217 I289 V297Y182-S186 VanDerWaalsContact O-CB 3.26Å; Y182-S186 WeakPolarHBondContact O-CB 3.4Å; Y182-S186 PolarHBondContact O-N 3Å; Y182-S186 PolarHBondContact O-OG 2.91Å; Y182-Y191 HydrophobicContact CD1-CE1 4.2Å; Y182-Y191 WeakPolarHBondContact CD1-OH 3.49Å; Y182-Y191 VanDerWaalsContact CE1-OH 3.3Å; Y182-Y191 WeakPolarHBondContact CE1-OH 3.33Å; Y182-L196 HydrophobicContact CD1-CD2 4.44Å; Y182-L196 HydrophobicContact CE1-CB 4.46Å; Y182-L196 HydrophobicContact CE1-CD2 4.48Å; Y182-V216 HydrophobicContact CD1-CG1 3.6Å; Y182-V216 HydrophobicContact CE1-CG1 4Å; Y182-V216 HydrophobicContact CG-CG1 4.4Å; Y182-K217 WeakPolarHBondContact CD2-O 3.31Å; Y182-K217 PolarHBondContact N-O 3.22Å; Y182-I289 HydrophobicContact CD1-CD1 4.49Å; Y182-I289 HydrophobicContact CG-CD1 4.48Å; Y182-V297 HydrophobicContact CD2-CG2 4.42Å; Y182-V297 HydrophobicContact CE2-CG2 4.28Å
183T98.9Very high98.6Very high0 Ų017.1 Ų17.10%010%0.096CC..Hα-helixtrans-71-50.2-176.669.10000110.3D181 S186 R187 N219 A242 G243 Q246 I289 G290D181-T183 PolarHBondContact O-N 2.96Å; D181-T183 WeakPolarHBondContact OD2-CA 3.25Å; D181-T183 VanDerWaalsContact OD2-CB 3.23Å; D181-T183 WeakPolarHBondContact OD2-CB 3.25Å; D181-T183 PolarHBondContact OD2-N 3.41Å; D181-T183 PolarHBondContact OD2-OG1 3.47Å; T183-S186 PolarHBondContact O-N 3.38Å; T183-S186 PolarHBondContact O-OG 3.12Å; T183-R187 WeakPolarHBondContact O-CG 3.47Å; T183-R187 PolarHBondContact O-N 3.15Å; T183-N219 WeakPolarHBondContact CG2-ND2 3.28Å; T183-A242 WeakPolarHBondContact OG1-CA 3.35Å; T183-G243 PolarHBondContact OG1-N 3.19Å; T183-Q246 HydrophobicContact CG2-CB 3.82Å; T183-Q246 HydrophobicContact CG2-CG 3.69Å; T183-I289 HydrophobicContact CG2-CG2 4.35Å; T183-G290 VanDerWaalsContact CG2-C 3.49Å; T183-G290 WeakPolarHBondContact CG2-O 3.39Å
184N98.9Very high98.6Very high0 Ų020.7 Ų20.70%011%0.11CC..Hα-helixtrans-61.7-44.6175-83.7-62.6000111.9N80 D165 S180 D181 S186 R187 G243N80-N184 PolarHBondContact ND2-OD1 3.27Å; N80-N184 PolarHBondContact OD1-ND2 3.36Å; N80-N184 PolarHBondContact OD1-OD1 3.07Å; D165-N184 VanDerWaalsContact CG-CG 3.43Å; D165-N184 PolarHBondContact OD1-ND2 2.88Å; D165-N184 PolarHBondContact OD2-ND2 3.3Å; S180-N184 WeakPolarHBondContact OG-CB 3.26Å; D181-N184 PolarHBondContact O-N 2.82Å; D181-N184 PolarHBondContact OD1-ND2 3.39Å; N184-S186 VanDerWaalsContact C-N 3.32Å; N184-S186 PolarHBondContact O-N 3.36Å; N184-R187 WeakPolarHBondContact O-CB 3.44Å; N184-R187 PolarHBondContact O-N 2.9Å; N184-G243 PolarHBondContact ND2-N 2.98Å; N184-G243 VanDerWaalsContact ND2-N 3.2Å
185A98.9Very high98.6Very high0 Ų023.5 Ų23.50%012%0.117CC..Hα-helixtrans-57.8-43.1176.400000112.1D181 R187 T188 Y191 W198 V216D181-A185 VanDerWaalsContact O-CB 3.31Å; D181-A185 WeakPolarHBondContact O-CB 3.36Å; D181-A185 PolarHBondContact O-N 3.2Å; A185-R187 PolarHBondContact O-N 3.37Å; A185-R187 VanDerWaalsContact O-N 3.11Å; A185-T188 WeakPolarHBondContact O-CB 3.49Å; A185-T188 WeakPolarHBondContact O-CG2 3.42Å; A185-T188 PolarHBondContact O-N 2.89Å; A185-T188 VanDerWaalsContact O-N 3.07Å; A185-T188 PolarHBondContact O-OG1 3.34Å; A185-Y191 HydrophobicContact CB-CD1 4.09Å; A185-Y191 HydrophobicContact CB-CD2 4.06Å; A185-Y191 HydrophobicContact CB-CE1 4.44Å; A185-Y191 HydrophobicContact CB-CE2 4.44Å; A185-Y191 HydrophobicContact CB-CG 3.87Å; A185-Y191 WeakPolarHBondContact O-CB 3.26Å; A185-W198 HydrophobicContact CB-CH2 4.15Å; A185-W198 HydrophobicContact CB-CZ2 4.49Å; A185-V216 HydrophobicContact CB-CB 4.39Å; A185-V216 HydrophobicContact CB-CG1 3.65Å; A185-V216 HydrophobicContact CB-CG2 3.75Å
186S98.8Very high98.6Very high0 Ų025.2 Ų25.20%012%0.12CC..Hα-helixtrans-61.9-19.4178.174.60000113.9L129 Y182 T183 N184 T288 I289L129-S186 WeakPolarHBondContact CD1-O 3.44Å; Y182-S186 VanDerWaalsContact O-CB 3.26Å; Y182-S186 WeakPolarHBondContact O-CB 3.4Å; Y182-S186 PolarHBondContact O-N 3Å; Y182-S186 PolarHBondContact O-OG 2.91Å; T183-S186 PolarHBondContact O-N 3.38Å; T183-S186 PolarHBondContact O-OG 3.12Å; N184-S186 VanDerWaalsContact C-N 3.32Å; N184-S186 PolarHBondContact O-N 3.36Å; S186-T288 PolarHBondContact OG-OG1 3.37Å; S186-I289 PolarHBondContact OG-N 3.23Å
187R98.8Very high98.7Very high0 Ų022.4 Ų22.40%011%0.105CC..THydrogen-bonded Turntrans-89.3-4.3178.1-59.9-43.5-64.7-146.2-25.7114.7R82 E83 Y134 F135 T183 N184 A185 M189 T288 E302R82-R187 HydrophobicContact CB-CG 4.29Å; E83-R187 HydrophobicContact CG-CB 4.08Å; E83-R187 VanDerWaalsContact OE1-CB 3.3Å; E83-R187 WeakPolarHBondContact OE1-CB 3.31Å; E83-R187 WeakPolarHBondContact OE1-CG 3.43Å; E83-R187 IonicContact OE1-CZ 3.87Å; E83-R187 IonicContact OE1-NE 3.13Å; E83-R187 PolarHBondContact OE1-NE 2.82Å; E83-R187 IonicContact OE1-NH2 3.82Å; E83-R187 PolarHBondContact OE1-NH2 3.46Å; Y134-R187 PolarHBondContact OH-NH2 3.13Å; F135-R187 WeakPolarHBondContact CD1-O 3.3Å; T183-R187 WeakPolarHBondContact O-CG 3.47Å; T183-R187 PolarHBondContact O-N 3.15Å; N184-R187 WeakPolarHBondContact O-CB 3.44Å; N184-R187 PolarHBondContact O-N 2.9Å; A185-R187 PolarHBondContact O-N 3.37Å; A185-R187 VanDerWaalsContact O-N 3.11Å; R187-M189 VanDerWaalsContact C-N 3.3Å; R187-M189 PolarHBondContact O-N 2.9Å; R187-T288 VanDerWaalsContact CD-OG1 3.26Å; R187-T288 WeakPolarHBondContact CD-OG1 3.49Å; R187-T288 PolarHBondContact NH1-OG1 2.91Å; R187-E302 IonicContact CZ-OE1 2.64Å; R187-E302 IonicContact CZ-OE2 3.56Å; R187-E302 IonicContact NH1-OE1 2.72Å; R187-E302 IonicContact NH1-OE2 3.33Å; R187-E302 PolarHBondContact NH1-OE2 3.01Å; R187-E302 IonicContact NH2-OE1 2.56Å; R187-E302 PolarHBondContact NH2-OE1 2.88Å; R187-E302 IonicContact NH2-OE2 2.81Å; R187-E302 PolarHBondContact NH2-OE2 3.32Å
188T98.9Very high98.7Very high1 Ų123.3 Ų23.31%0.00611%0.105CC..SBendtrans-76.5-19-17661.30000113.5S136 A137 F161 T163 A185 M190 Y191 W198S136-T188 PolarHBondContact N-O 3.36Å; A137-T188 VanDerWaalsContact CB-O 3.27Å; A137-T188 WeakPolarHBondContact CB-O 3.39Å; A137-T188 PolarHBondContact N-O 3.44Å; F161-T188 HydrophobicContact CE1-CG2 4.24Å; F161-T188 HydrophobicContact CZ-CG2 4.04Å; T163-T188 HydrophobicContact CG2-CG2 4.33Å; A185-T188 WeakPolarHBondContact O-CB 3.49Å; A185-T188 WeakPolarHBondContact O-CG2 3.42Å; A185-T188 PolarHBondContact O-N 2.89Å; A185-T188 VanDerWaalsContact O-N 3.07Å; A185-T188 PolarHBondContact O-OG1 3.34Å; T188-M190 HydrophobicContact CG2-CE 4.33Å; T188-M190 PolarHBondContact O-N 2.81Å; T188-M190 PolarHBondContact OG1-N 2.97Å; T188-Y191 PolarHBondContact OG1-N 3.13Å; T188-W198 HydrophobicContact CG2-CH2 4.03Å; T188-W198 HydrophobicContact CG2-CZ3 4.09Å; T188-W198 WeakPolarHBondContact OG1-CZ3 3.41Å
189M98.8Very high98.7Very high0 Ų022.1 Ų22.10%010%0.1CC..SBendtrans6310.7-163.5-159-1768100113.6L114 I123 L129 F135 A137 T138 R187 I202 L206L114-M189 HydrophobicContact CD1-CE 4.41Å; I123-M189 HydrophobicContact CG2-CG 3.58Å; I123-M189 HydrophobicContact CG2-SD 3.91Å; L129-M189 HydrophobicContact CD1-CB 4.01Å; L129-M189 HydrophobicContact CD1-CG 4.47Å; F135-M189 HydrophobicContact CB-CB 3.77Å; F135-M189 HydrophobicContact CD2-SD 4.28Å; F135-M189 HydrophobicContact CG-CB 4.34Å; A137-M189 HydrophobicContact CB-CB 3.92Å; A137-M189 HydrophobicContact CB-CE 3.66Å; T138-M189 HydrophobicContact CG2-CE 4.12Å; R187-M189 VanDerWaalsContact C-N 3.3Å; R187-M189 PolarHBondContact O-N 2.9Å; M189-I202 WeakPolarHBondContact O-CG2 3.47Å; M189-L206 HydrophobicContact CE-CD1 4.4Å
190M98.8Very high98.7Very high0 Ų026.3 Ų26.30%012%0.12CC..SBendtrans-114.8-7.5177.1-56-178.1-74.500112.9A137 V140 F161 T188 W198 D199 L203 I208 L213A137-M190 HydrophobicContact CB-CG 3.54Å; A137-M190 HydrophobicContact CB-SD 4.21Å; V140-M190 HydrophobicContact CG2-CE 4.11Å; F161-M190 HydrophobicContact CD1-CE 4.09Å; F161-M190 HydrophobicContact CE1-CE 3.45Å; F161-M190 VanDerWaalsContact CE1-CE 3.45Å; F161-M190 HydrophobicContact CE2-CE 4.29Å; F161-M190 HydrophobicContact CZ-CE 3.57Å; T188-M190 HydrophobicContact CG2-CE 4.33Å; T188-M190 PolarHBondContact O-N 2.81Å; T188-M190 PolarHBondContact OG1-N 2.97Å; M190-W198 HydrophobicContact CB-CE3 3.92Å; M190-W198 HydrophobicContact CB-CZ3 3.94Å; M190-W198 HydrophobicContact CE-CZ3 4.47Å; M190-D199 PolarHBondContact O-N 2.98Å; M190-L203 HydrophobicContact CB-CD2 4.18Å; M190-L203 HydrophobicContact CG-CD2 4.37Å; M190-L203 HydrophobicContact SD-CD2 4.03Å; M190-I208 HydrophobicContact SD-CD1 3.52Å; M190-I208 VanDerWaalsContact SD-CD1 3.52Å; M190-I208 HydrophobicContact SD-CG2 4.22Å; M190-L213 HydrophobicContact CE-CD2 4.23Å; M190-L213 HydrophobicContact SD-CD2 4.48Å
191Y98.9Very high98.7Very high4 Ų431.2 Ų31.22%0.01614%0.143CC..EExtended strand (participates in β ladder)trans-105.5126.6-176.4-166.5-105000110.8Y182 A185 T188 I193 L196 K197 W198 V216 I289Y182-Y191 HydrophobicContact CD1-CE1 4.2Å; Y182-Y191 WeakPolarHBondContact CD1-OH 3.49Å; Y182-Y191 VanDerWaalsContact CE1-OH 3.3Å; Y182-Y191 WeakPolarHBondContact CE1-OH 3.33Å; A185-Y191 HydrophobicContact CB-CD1 4.09Å; A185-Y191 HydrophobicContact CB-CD2 4.06Å; A185-Y191 HydrophobicContact CB-CE1 4.44Å; A185-Y191 HydrophobicContact CB-CE2 4.44Å; A185-Y191 HydrophobicContact CB-CG 3.87Å; A185-Y191 WeakPolarHBondContact O-CB 3.26Å; T188-Y191 PolarHBondContact OG1-N 3.13Å; Y191-I193 PolarHBondContact O-N 3.17Å; Y191-L196 HydrophobicContact CE1-CD2 4.36Å; Y191-L196 VanDerWaalsContact OH-CA 3.32Å; Y191-L196 WeakPolarHBondContact OH-CA 3.02Å; Y191-L196 PolarHBondContact OH-O 3.39Å; Y191-K197 VanDerWaalsContact CE2-CA 3.45Å; Y191-W198 AromaticContact CD2-CD2 3.87Å; Y191-W198 HydrophobicContact CD2-CD2 3.87Å; Y191-W198 AromaticContact CD2-CE3 3.89Å; Y191-W198 HydrophobicContact CD2-CE3 3.89Å; Y191-W198 HydrophobicContact CD2-CG 4.29Å; Y191-W198 HydrophobicContact CD2-CZ3 4.26Å; Y191-W198 HydrophobicContact CG-CE3 4.45Å; Y191-V216 HydrophobicContact CD2-CG2 4.03Å; Y191-V216 HydrophobicContact CE1-CG1 4.42Å; Y191-V216 HydrophobicContact CE2-CB 3.84Å; Y191-V216 HydrophobicContact CE2-CG1 3.89Å; Y191-V216 HydrophobicContact CE2-CG2 3.64Å; Y191-I289 HydrophobicContact CE1-CD1 4.14Å
192N98.8Very high98.6Very high11 Ų1131.2 Ų31.26%0.05914%0.143CC..EExtended strand (participates in β ladder)trans-78.5113.4174.6-169.7-50.6000109.4K126 Y194 D195 L196 K197 D199K126-N192 CarbonylContact O-C 3.45Å; K126-N192 VanDerWaalsContact O-CA 3.29Å; K126-N192 WeakPolarHBondContact O-CA 3.38Å; K126-N192 PolarHBondContact O-OD1 3.11Å; N192-Y194 VanDerWaalsContact C-N 3.26Å; N192-Y194 PolarHBondContact O-N 3.13Å; N192-Y194 PolarHBondContact OD1-N 3.23Å; N192-D195 HydrophobicContact CB-CB 4.24Å; N192-D195 PolarHBondContact OD1-N 2.84Å; N192-L196 WeakPolarHBondContact O-CA 3.23Å; N192-L196 PolarHBondContact O-N 3.39Å; N192-K197 WeakPolarHBondContact CB-O 3.31Å; N192-K197 PolarHBondContact N-O 2.84Å; N192-K197 PolarHBondContact O-N 2.95Å; N192-D199 HydrophobicContact CB-CB 4.1Å; N192-D199 PolarHBondContact ND2-OD2 2.79Å
193I98.6Very high98.6Very high0 Ų029 Ų290%013%0.134CC..THydrogen-bonded Turntrans-77.5-12.5-173.566.8166.7000113.2K126 T127 Y191 L196 T287 I289 Y299K126-I193 PolarHBondContact O-N 3.39Å; T127-I193 WeakPolarHBondContact O-CG2 3.32Å; Y191-I193 PolarHBondContact O-N 3.17Å; I193-L196 WeakPolarHBondContact O-CD2 3.48Å; I193-T287 HydrophobicContact CD1-CG2 3.97Å; I193-I289 HydrophobicContact CB-CD1 4.16Å; I193-I289 HydrophobicContact CB-CG1 4.07Å; I193-I289 HydrophobicContact CG2-CD1 4.2Å; I193-I289 HydrophobicContact CG2-CG1 4.13Å; I193-Y299 HydrophobicContact CB-CE1 4.19Å; I193-Y299 HydrophobicContact CD1-CD1 4.33Å; I193-Y299 HydrophobicContact CD1-CE1 4.16Å; I193-Y299 HydrophobicContact CG1-CE1 4.3Å; I193-Y299 WeakPolarHBondContact O-CE1 3.29Å; I193-Y299 PolarHBondContact O-OH 2.82Å
194Y97.5Very high98.6Very high83 Ų8334.1 Ų34.133%0.32516%0.161SC..THydrogen-bonded Turntrans-94.6-45.1-179.9-53.3-88.7000110.9K125 K126 N192 L196 P278K125-Y194 WeakPolarHBondContact O-CD2 3.21Å; K125-Y194 WeakPolarHBondContact O-CE2 3.44Å; K126-Y194 WeakPolarHBondContact O-CD2 3.46Å; N192-Y194 VanDerWaalsContact C-N 3.26Å; N192-Y194 PolarHBondContact O-N 3.13Å; N192-Y194 PolarHBondContact OD1-N 3.23Å; Y194-L196 VanDerWaalsContact C-N 3.33Å; Y194-P278 HydrophobicContact CD1-CG 3.93Å; Y194-P278 HydrophobicContact CE1-CB 4.08Å; Y194-P278 HydrophobicContact CE1-CG 3.54Å
195D97.8Very high98.6Very high92 Ų9236.7 Ų36.749%0.49218%0.175SC..THydrogen-bonded Turntrans-83.1-10.8177.2-77.60.4000113.1N192 K197N192-D195 HydrophobicContact CB-CB 4.24Å; N192-D195 PolarHBondContact OD1-N 2.84Å; D195-K197 HydrophobicContact CB-CD 4.02Å; D195-K197 HydrophobicContact CB-CG 3.95Å; D195-K197 PolarHBondContact O-N 2.97Å; D195-K197 WeakPolarHBondContact OD2-CE 3.38Å; D195-K197 IonicContact OD2-NZ 3.71Å; D195-K197 PolarHBondContact OD2-NZ 3.29Å
196L98.4Very high98.6Very high59 Ų5936.9 Ų36.931%0.30918%0.176SC..THydrogen-bonded Turntrans5349.4-177.3-56.9176.3000113.1Y182 Y191 N192 I193 Y194 I289 V297Y182-L196 HydrophobicContact CD1-CD2 4.44Å; Y182-L196 HydrophobicContact CE1-CB 4.46Å; Y182-L196 HydrophobicContact CE1-CD2 4.48Å; Y191-L196 HydrophobicContact CE1-CD2 4.36Å; Y191-L196 VanDerWaalsContact OH-CA 3.32Å; Y191-L196 WeakPolarHBondContact OH-CA 3.02Å; Y191-L196 PolarHBondContact OH-O 3.39Å; N192-L196 WeakPolarHBondContact O-CA 3.23Å; N192-L196 PolarHBondContact O-N 3.39Å; I193-L196 WeakPolarHBondContact O-CD2 3.48Å; Y194-L196 VanDerWaalsContact C-N 3.33Å; L196-I289 HydrophobicContact CD2-CD1 3.72Å; L196-V297 HydrophobicContact CD1-CG2 3.7Å; L196-V297 HydrophobicContact CD2-CG1 4.42Å; L196-V297 HydrophobicContact CD2-CG2 4.21Å
197K98.6Very high98.6Very high108 Ų10840 Ų4047%0.4719%0.192SC..EExtended strand (participates in β ladder)trans-150.7158.7177.768.7-168.9-179.3-149.70111.7Y191 N192 D195 D199Y191-K197 VanDerWaalsContact CE2-CA 3.45Å; N192-K197 WeakPolarHBondContact CB-O 3.31Å; N192-K197 PolarHBondContact N-O 2.84Å; N192-K197 PolarHBondContact O-N 2.95Å; D195-K197 HydrophobicContact CB-CD 4.02Å; D195-K197 HydrophobicContact CB-CG 3.95Å; D195-K197 PolarHBondContact O-N 2.97Å; D195-K197 WeakPolarHBondContact OD2-CE 3.38Å; D195-K197 IonicContact OD2-NZ 3.71Å; D195-K197 PolarHBondContact OD2-NZ 3.29Å; K197-D199 PolarHBondContact O-N 2.98Å
198W98.8Very high98.6Very high48 Ų4840.2 Ų40.218%0.18219%0.193CC..EExtended strand (participates in β ladder)trans-57130.4167.2-62.6117.1000110.5F161 A185 T188 M190 Y191 Q200 L203 L213 P214 V216F161-W198 HydrophobicContact CE1-CH2 4.45Å; A185-W198 HydrophobicContact CB-CH2 4.15Å; A185-W198 HydrophobicContact CB-CZ2 4.49Å; T188-W198 HydrophobicContact CG2-CH2 4.03Å; T188-W198 HydrophobicContact CG2-CZ3 4.09Å; T188-W198 WeakPolarHBondContact OG1-CZ3 3.41Å; M190-W198 HydrophobicContact CB-CE3 3.92Å; M190-W198 HydrophobicContact CB-CZ3 3.94Å; M190-W198 HydrophobicContact CE-CZ3 4.47Å; Y191-W198 AromaticContact CD2-CD2 3.87Å; Y191-W198 HydrophobicContact CD2-CD2 3.87Å; Y191-W198 AromaticContact CD2-CE3 3.89Å; Y191-W198 HydrophobicContact CD2-CE3 3.89Å; Y191-W198 HydrophobicContact CD2-CG 4.29Å; Y191-W198 HydrophobicContact CD2-CZ3 4.26Å; Y191-W198 HydrophobicContact CG-CE3 4.45Å; W198-Q200 PolarHBondContact O-N 2.66Å; W198-L203 HydrophobicContact CB-CD1 4.34Å; W198-L213 HydrophobicContact CB-CD1 3.9Å; W198-L213 HydrophobicContact CD2-CB 4.3Å; W198-L213 HydrophobicContact CD2-CD1 3.84Å; W198-L213 HydrophobicContact CD2-CD2 4.41Å; W198-L213 HydrophobicContact CD2-CG 4.41Å; W198-L213 HydrophobicContact CE3-CD1 4.26Å; W198-L213 HydrophobicContact CE3-CD2 4.36Å; W198-L213 HydrophobicContact CG-CB 4.41Å; W198-L213 HydrophobicContact CG-CD1 3.65Å; W198-L213 HydrophobicContact CZ2-CB 4.42Å; W198-L213 HydrophobicContact CZ3-CD2 4.47Å; W198-P214 HydrophobicContact CZ2-CG 4.03Å; W198-P214 PolarHBondContact NE1-O 2.74Å; W198-V216 HydrophobicContact CH2-CG2 4.31Å; W198-V216 HydrophobicContact CZ2-CG2 3.42Å; W198-V216 VanDerWaalsContact CZ2-CG2 3.42Å
199D98.8Very high98.5Very high9 Ų940.6 Ų40.65%0.04820%0.196CC..  trans-89.7108.1-173-162.2-74.8000111.3K126 M190 N192 K197 E201 I202 L203K126-D199 WeakPolarHBondContact CD-OD2 3.5Å; K126-D199 VanDerWaalsContact NZ-CG 3.31Å; K126-D199 IonicContact NZ-OD1 2.98Å; K126-D199 PolarHBondContact NZ-OD1 3.13Å; K126-D199 IonicContact NZ-OD2 3.75Å; K126-D199 PolarHBondContact NZ-OD2 3.04Å; M190-D199 PolarHBondContact O-N 2.98Å; N192-D199 HydrophobicContact CB-CB 4.1Å; N192-D199 PolarHBondContact ND2-OD2 2.79Å; K197-D199 PolarHBondContact O-N 2.98Å; D199-E201 VanDerWaalsContact C-N 3.26Å; D199-E201 PolarHBondContact O-N 2.63Å; D199-E201 WeakPolarHBondContact OD1-CB 3.15Å; D199-E201 PolarHBondContact OD1-N 3.4Å; D199-E201 VanDerWaalsContact OD1-N 3.17Å; D199-I202 HydrophobicContact CB-CB 4.33Å; D199-I202 HydrophobicContact CB-CD1 3.92Å; D199-I202 HydrophobicContact CB-CG1 4.03Å; D199-I202 PolarHBondContact O-N 3.13Å; D199-I202 PolarHBondContact OD1-N 3.26Å; D199-L203 WeakPolarHBondContact O-CG 3.47Å; D199-L203 PolarHBondContact O-N 3.21Å; D199-L203 VanDerWaalsContact O-N 3.07Å
200Q98.5Very high98.5Very high89 Ų8946.3 Ų46.342%0.41622%0.221SC..Hα-helixtrans-60.2-33.7-176.1-169.163.456.500113.1W198 I202 L203 D204W198-Q200 PolarHBondContact O-N 2.66Å; Q200-I202 VanDerWaalsContact C-N 3.33Å; Q200-I202 PolarHBondContact O-N 3.23Å; Q200-L203 PolarHBondContact O-N 3.25Å; Q200-D204 PolarHBondContact NE2-OD1 3.42Å; Q200-D204 WeakPolarHBondContact O-CB 3.32Å; Q200-D204 PolarHBondContact O-N 2.86Å
201E98.6Very high98.5Very high104 Ų10450.6 Ų50.649%0.48624%0.241SC..Hα-helixtrans-66.3-38.2-179.8-172.2-179.3169.900111.3K126 D199 L205K126-E201 WeakPolarHBondContact CE-OE2 3.31Å; K126-E201 IonicContact NZ-OE2 3.03Å; K126-E201 PolarHBondContact NZ-OE2 3.39Å; D199-E201 VanDerWaalsContact C-N 3.26Å; D199-E201 PolarHBondContact O-N 2.63Å; D199-E201 WeakPolarHBondContact OD1-CB 3.15Å; D199-E201 PolarHBondContact OD1-N 3.4Å; D199-E201 VanDerWaalsContact OD1-N 3.17Å; E201-L205 VanDerWaalsContact O-CB 3.28Å; E201-L205 WeakPolarHBondContact O-CB 3.27Å; E201-L205 PolarHBondContact O-N 3.33Å
202I98.7Very high98.4Very high0 Ų050.5 Ų50.50%024%0.241CC..Hα-helixtrans-71.9-40.7176.4-56.3178.2000111.1M122 I123 K126 T127 M189 D199 Q200 L205 L206M122-I202 HydrophobicContact CE-CG1 4.43Å; M122-I202 HydrophobicContact SD-CG1 4.03Å; I123-I202 HydrophobicContact CD1-CB 4.43Å; I123-I202 HydrophobicContact CD1-CD1 3.7Å; I123-I202 HydrophobicContact CD1-CG1 3.74Å; I123-I202 HydrophobicContact CD1-CG2 3.93Å; K126-I202 HydrophobicContact CB-CD1 4.24Å; K126-I202 HydrophobicContact CD-CD1 4.04Å; K126-I202 HydrophobicContact CD-CG1 4.14Å; T127-I202 HydrophobicContact CG2-CD1 3.53Å; M189-I202 WeakPolarHBondContact O-CG2 3.47Å; D199-I202 HydrophobicContact CB-CB 4.33Å; D199-I202 HydrophobicContact CB-CD1 3.92Å; D199-I202 HydrophobicContact CB-CG1 4.03Å; D199-I202 PolarHBondContact O-N 3.13Å; D199-I202 PolarHBondContact OD1-N 3.26Å; Q200-I202 VanDerWaalsContact C-N 3.33Å; Q200-I202 PolarHBondContact O-N 3.23Å; I202-L205 PolarHBondContact O-N 2.91Å; I202-L206 HydrophobicContact CG2-CD1 4.03Å; I202-L206 PolarHBondContact O-N 2.86Å; I202-L206 VanDerWaalsContact O-N 3.1Å
203L98.8Very high98.4Very high1 Ų150.9 Ų50.91%0.00524%0.243CC..Hα-helixtrans-61.4-44.9176.6-65.7175.5000111.3M190 W198 D199 Q200 L206 D207 I208 K210 L213M190-L203 HydrophobicContact CB-CD2 4.18Å; M190-L203 HydrophobicContact CG-CD2 4.37Å; M190-L203 HydrophobicContact SD-CD2 4.03Å; W198-L203 HydrophobicContact CB-CD1 4.34Å; D199-L203 WeakPolarHBondContact O-CG 3.47Å; D199-L203 PolarHBondContact O-N 3.21Å; D199-L203 VanDerWaalsContact O-N 3.07Å; Q200-L203 PolarHBondContact O-N 3.25Å; L203-L206 PolarHBondContact O-N 3.14Å; L203-D207 WeakPolarHBondContact O-CA 3.48Å; L203-D207 PolarHBondContact O-N 3.49Å; L203-I208 HydrophobicContact CD2-CB 4.01Å; L203-I208 HydrophobicContact CD2-CG2 3.92Å; L203-I208 PolarHBondContact O-N 3.36Å; L203-K210 HydrophobicContact CD1-CB 4.18Å; L203-L213 HydrophobicContact CD1-CD1 3.58Å; L203-L213 HydrophobicContact CD2-CD1 3.85Å; L203-L213 HydrophobicContact CD2-CD2 4.5Å; L203-L213 HydrophobicContact CG-CD1 4.37Å
204D98.5Very high98.5Very high107 Ų10751 Ų5157%0.57224%0.243SC*.Hα-helixtrans-64.5-42.6176.9-68.5-14.7000111.2Q200 L206 D207Q200-D204 PolarHBondContact NE2-OD1 3.42Å; Q200-D204 WeakPolarHBondContact O-CB 3.32Å; Q200-D204 PolarHBondContact O-N 2.86Å; D204-L206 VanDerWaalsContact C-N 3.28Å; D204-L206 PolarHBondContact O-N 3.21Å; D204-D207 PolarHBondContact O-N 2.86Å
205L98.6Very high98.5Very high55 Ų5553.3 Ų53.329%0.28826%0.257SS..Hα-helixtrans-57.9-39.3177.5175.261.7000112.5L114 H119 M122 E201 I202L114-L205 HydrophobicContact CD2-CD1 4.31Å; L114-L205 HydrophobicContact CD2-CD2 3.93Å; L114-L205 HydrophobicContact CD2-CG 4.02Å; H119-L205 HydrophobicContact CB-CD2 4.22Å; H119-L205 WeakPolarHBondContact NE2-CD1 3.24Å; M122-L205 HydrophobicContact CE-CD2 3.64Å; E201-L205 VanDerWaalsContact O-CB 3.28Å; E201-L205 WeakPolarHBondContact O-CB 3.27Å; E201-L205 PolarHBondContact O-N 3.33Å; I202-L205 PolarHBondContact O-N 2.91Å
206L98.5Very high98.6Very high3 Ų350.3 Ų50.32%0.01624%0.242CC..Hα-helixtrans-95.4-1.3-178.4-63.9172.9000113.6L114 A137 K141 M189 I202 L203 D204 I208L114-L206 HydrophobicContact CD1-CD2 3.74Å; L114-L206 HydrophobicContact CD2-CD2 3.92Å; L114-L206 HydrophobicContact CG-CD2 4.37Å; A137-L206 HydrophobicContact CB-CD1 3.55Å; K141-L206 HydrophobicContact CD-CB 4.3Å; K141-L206 HydrophobicContact CD-CD2 3.74Å; M189-L206 HydrophobicContact CE-CD1 4.4Å; I202-L206 HydrophobicContact CG2-CD1 4.03Å; I202-L206 PolarHBondContact O-N 2.86Å; I202-L206 VanDerWaalsContact O-N 3.1Å; L203-L206 PolarHBondContact O-N 3.14Å; D204-L206 VanDerWaalsContact C-N 3.28Å; D204-L206 PolarHBondContact O-N 3.21Å; L206-I208 VanDerWaalsContact C-N 3.31Å; L206-I208 HydrophobicContact CB-CD1 3.68Å; L206-I208 HydrophobicContact CB-CG1 3.77Å; L206-I208 HydrophobicContact CD1-CD1 3.98Å; L206-I208 PolarHBondContact O-N 3.2Å
207D98.3Very high98.6Very high65 Ų6549.9 Ų49.935%0.34824%0.238SC..THydrogen-bonded Turntrans50.250.9-172.7-17734.3000111.7R151 R155 L203 D204R151-D207 VanDerWaalsContact CD-OD2 3.28Å; R151-D207 WeakPolarHBondContact CD-OD2 3.48Å; R151-D207 IonicContact CZ-OD2 3.17Å; R151-D207 IonicContact NE-OD2 3.91Å; R151-D207 VanDerWaalsContact NH1-CB 3.34Å; R151-D207 VanDerWaalsContact NH1-CG 3.28Å; R151-D207 PolarHBondContact NH1-O 3.03Å; R151-D207 IonicContact NH1-OD2 3.09Å; R151-D207 PolarHBondContact NH1-OD2 3.34Å; R155-D207 IonicContact CZ-OD1 3.71Å; R155-D207 IonicContact NH2-OD1 3.33Å; R155-D207 PolarHBondContact NH2-OD1 3.42Å; R155-D207 IonicContact NH2-OD2 2.88Å; R155-D207 PolarHBondContact NH2-OD2 2.84Å; L203-D207 WeakPolarHBondContact O-CA 3.48Å; L203-D207 PolarHBondContact O-N 3.49Å; D204-D207 PolarHBondContact O-N 2.86Å
208I98.7Very high98.6Very high5 Ų545.6 Ų45.63%0.02622%0.221CC..  trans-100.2114.4176.9-62.6175.2000108.7V140 M190 L203 L206 K210 I212V140-I208 HydrophobicContact CB-CD1 4.03Å; V140-I208 HydrophobicContact CG1-CD1 3.85Å; V140-I208 HydrophobicContact CG1-CG1 4.02Å; V140-I208 HydrophobicContact CG1-CG2 3.86Å; M190-I208 HydrophobicContact SD-CD1 3.52Å; M190-I208 VanDerWaalsContact SD-CD1 3.52Å; M190-I208 HydrophobicContact SD-CG2 4.22Å; L203-I208 HydrophobicContact CD2-CB 4.01Å; L203-I208 HydrophobicContact CD2-CG2 3.92Å; L203-I208 PolarHBondContact O-N 3.36Å; L206-I208 VanDerWaalsContact C-N 3.31Å; L206-I208 HydrophobicContact CB-CD1 3.68Å; L206-I208 HydrophobicContact CB-CG1 3.77Å; L206-I208 HydrophobicContact CD1-CD1 3.98Å; L206-I208 PolarHBondContact O-N 3.2Å; I208-K210 PolarHBondContact O-N 3.35Å; I208-I212 HydrophobicContact CG2-CD1 3.79Å; I208-I212 HydrophobicContact CG2-CG1 4.46Å
209P98.2Very high98.6Very high10 Ų1043.3 Ų43.37%0.06521%0.213CC..  trans-62.8130.8177.8-22.334.7000111A154 R155 E211 I212A154-P209 HydrophobicContact CB-CB 4.41Å; A154-P209 HydrophobicContact CB-CG 3.9Å; R155-P209 HydrophobicContact CG-CB 4Å; R155-P209 HydrophobicContact CG-CG 3.55Å; P209-E211 WeakPolarHBondContact CB-OE2 3.26Å; P209-E211 PolarHBondContact O-N 3.01Å; P209-I212 WeakPolarHBondContact O-CG1 3.46Å; P209-I212 PolarHBondContact O-N 3.4Å
210K98.1Very high98.6Very high120 Ų12043.7 Ų43.752%0.52222%0.216SC..G310 helixtrans-65.8-20.7-179.566.8-179.3-178.4-176.70113.1L203 I208 I212 L213L203-K210 HydrophobicContact CD1-CB 4.18Å; I208-K210 PolarHBondContact O-N 3.35Å; K210-I212 PolarHBondContact O-N 2.99Å; K210-L213 HydrophobicContact CB-CD1 4.26Å; K210-L213 WeakPolarHBondContact O-CB 3.47Å; K210-L213 WeakPolarHBondContact O-CG 3.49Å; K210-L213 PolarHBondContact O-N 3.41Å; K210-L213 VanDerWaalsContact O-N 3.13Å
211E97.9Very high98.6Very high90 Ų9042.4 Ų42.442%0.42121%0.21SC..G310 helixtrans-62.4-21.5-176.8-68.268.6-151.300112.9P209P209-E211 WeakPolarHBondContact CB-OE2 3.26Å; P209-E211 PolarHBondContact O-N 3.01Å
212I98.6Very high98.6Very high1 Ų140.3 Ų40.31%0.00520%0.204CC..G310 helixtrans-85.1-11.7179.175.9-177.6000113.1V140 L144 A154 L159 F161 H178 I208 P209 K210V140-I212 HydrophobicContact CG1-CD1 3.89Å; L144-I212 HydrophobicContact CD1-CD1 4.49Å; A154-I212 HydrophobicContact CB-CG2 3.57Å; L159-I212 HydrophobicContact CB-CG2 4.48Å; L159-I212 WeakPolarHBondContact O-CG2 3.44Å; F161-I212 HydrophobicContact CB-CB 4.09Å; F161-I212 HydrophobicContact CB-CD1 3.74Å; F161-I212 HydrophobicContact CB-CG1 3.68Å; F161-I212 PolarHBondContact N-O 3.16Å; H178-I212 PolarHBondContact CE1-O 3.18Å; H178-I212 VanDerWaalsContact CE1-O 3.25Å; I208-I212 HydrophobicContact CG2-CD1 3.79Å; I208-I212 HydrophobicContact CG2-CG1 4.46Å; P209-I212 WeakPolarHBondContact O-CG1 3.46Å; P209-I212 PolarHBondContact O-N 3.4Å; K210-I212 PolarHBondContact O-N 2.99Å
213L98.8Very high98.6Very high19 Ų1940.8 Ų40.810%0.09921%0.206CC..PPolyproline II helixtrans-82.9138.1-167.7-58.7173000111.6F161 M190 W198 L203 K210F161-L213 HydrophobicContact CD1-CD2 3.87Å; F161-L213 HydrophobicContact CE1-CD2 4.36Å; M190-L213 HydrophobicContact CE-CD2 4.23Å; M190-L213 HydrophobicContact SD-CD2 4.48Å; W198-L213 HydrophobicContact CB-CD1 3.9Å; W198-L213 HydrophobicContact CD2-CB 4.3Å; W198-L213 HydrophobicContact CD2-CD1 3.84Å; W198-L213 HydrophobicContact CD2-CD2 4.41Å; W198-L213 HydrophobicContact CD2-CG 4.41Å; W198-L213 HydrophobicContact CE3-CD1 4.26Å; W198-L213 HydrophobicContact CE3-CD2 4.36Å; W198-L213 HydrophobicContact CG-CB 4.41Å; W198-L213 HydrophobicContact CG-CD1 3.65Å; W198-L213 HydrophobicContact CZ2-CB 4.42Å; W198-L213 HydrophobicContact CZ3-CD2 4.47Å; L203-L213 HydrophobicContact CD1-CD1 3.58Å; L203-L213 HydrophobicContact CD2-CD1 3.85Å; L203-L213 HydrophobicContact CD2-CD2 4.5Å; L203-L213 HydrophobicContact CG-CD1 4.37Å; K210-L213 HydrophobicContact CB-CD1 4.26Å; K210-L213 WeakPolarHBondContact O-CB 3.47Å; K210-L213 WeakPolarHBondContact O-CG 3.49Å; K210-L213 PolarHBondContact O-N 3.41Å; K210-L213 VanDerWaalsContact O-N 3.13Å
214P98.8Very high98.6Very high3 Ų341.3 Ų41.32%0.01921%0.212CC..PPolyproline II helixtrans-71.9160.7175.728.1-31.4000112.1T166 H178 W198T166-P214 HydrophobicContact CG2-CB 3.85Å; T166-P214 HydrophobicContact CG2-CG 4.09Å; H178-P214 VanDerWaalsContact CE1-CA 3.41Å; H178-P214 WeakPolarHBondContact CE1-CA 3.47Å; H178-P214 VanDerWaalsContact CE1-N 3.33Å; W198-P214 HydrophobicContact CZ2-CG 4.03Å; W198-P214 PolarHBondContact NE1-O 2.74Å
215E98.7Very high98.6Very high131 Ų13142.5 Ų42.561%0.61221%0.209SC*.EExtended strand (participates in β ladder)trans-62.2140.6162.3-67.4-174.8178.500109.8H178 V179 S180 K217H178-E215 PolarHBondContact O-N 2.6Å; V179-E215 CarbonylContact C-O 3.57Å; V179-E215 VanDerWaalsContact CA-O 3.28Å; V179-E215 WeakPolarHBondContact CA-O 3.46Å; V179-E215 HydrophobicContact CG2-CB 4.48Å; V179-E215 WeakPolarHBondContact CG2-O 3.25Å; S180-E215 PolarHBondContact N-O 3.23Å; E215-K217 WeakPolarHBondContact OE2-CE 3.49Å; E215-K217 IonicContact OE2-NZ 3.99Å
216V98.8Very high98.6Very high30 Ų3040 Ų4018%0.18220%0.196CC..EExtended strand (participates in β ladder)trans-106.3127.1176.6-176.60000109.5S180 Y182 A185 Y191 W198S180-V216 CarbonylContact O-C 3.58Å; S180-V216 WeakPolarHBondContact O-CA 3.2Å; Y182-V216 HydrophobicContact CD1-CG1 3.6Å; Y182-V216 HydrophobicContact CE1-CG1 4Å; Y182-V216 HydrophobicContact CG-CG1 4.4Å; A185-V216 HydrophobicContact CB-CB 4.39Å; A185-V216 HydrophobicContact CB-CG1 3.65Å; A185-V216 HydrophobicContact CB-CG2 3.75Å; Y191-V216 HydrophobicContact CD2-CG2 4.03Å; Y191-V216 HydrophobicContact CE1-CG1 4.42Å; Y191-V216 HydrophobicContact CE2-CB 3.84Å; Y191-V216 HydrophobicContact CE2-CG1 3.89Å; Y191-V216 HydrophobicContact CE2-CG2 3.64Å; W198-V216 HydrophobicContact CH2-CG2 4.31Å; W198-V216 HydrophobicContact CZ2-CG2 3.42Å; W198-V216 VanDerWaalsContact CZ2-CG2 3.42Å
217K98.8Very high98.5Very high50 Ų5040.5 Ų40.522%0.21720%0.201CC..EExtended strand (participates in β ladder)trans-126.8176-174.5-66.6-163.2-177.8-172.50112.2V179 S180 D181 Y182 E215 E221 Y223V179-K217 HydrophobicContact CG2-CB 4.02Å; V179-K217 HydrophobicContact CG2-CD 3.69Å; V179-K217 HydrophobicContact CG2-CG 3.62Å; S180-K217 PolarHBondContact O-N 3.35Å; D181-K217 CarbonylContact C-O 3.55Å; D181-K217 WeakPolarHBondContact CA-O 3.46Å; Y182-K217 WeakPolarHBondContact CD2-O 3.31Å; Y182-K217 PolarHBondContact N-O 3.22Å; E215-K217 WeakPolarHBondContact OE2-CE 3.49Å; E215-K217 IonicContact OE2-NZ 3.99Å; K217-E221 WeakPolarHBondContact CD-OE2 3.35Å; K217-Y223 HydrophobicContact CB-CD1 4.29Å; K217-Y223 HydrophobicContact CB-CE1 4.23Å; K217-Y223 HydrophobicContact CD-CD1 4.2Å
218S98.7Very high98.3Very high17 Ų1740.9 Ų40.912%0.11920%0.203CC..  trans-68.4172.8174.375.40000111.5E221 Y223S218-E221 VanDerWaalsContact CB-OE1 3.32Å; S218-E221 WeakPolarHBondContact CB-OE1 3.23Å; S218-E221 PolarHBondContact N-OE1 3.44Å; S218-E221 WeakPolarHBondContact OG-CG 3.45Å; S218-E221 PolarHBondContact OG-OE1 3.21Å; S218-Y223 WeakPolarHBondContact O-CE1 3.23Å; S218-Y223 PolarHBondContact O-OH 3.21Å; S218-Y223 VanDerWaalsContact O-OH 3.1Å
219N98.9Very high98.2Very high0 Ų047.9 Ų47.90%023%0.23CC..SBendtrans-87.6-12.6-176.3-69.354.3000113D181 T183 Y223 G240 M241 G292 L445D181-N219 PolarHBondContact OD2-ND2 3.46Å; D181-N219 PolarHBondContact OD2-OD1 3.33Å; T183-N219 WeakPolarHBondContact CG2-ND2 3.28Å; N219-Y223 PolarHBondContact O-OH 2.64Å; N219-G240 WeakPolarHBondContact O-CA 3.39Å; N219-M241 WeakPolarHBondContact CA-O 3.3Å; N219-M241 VanDerWaalsContact CB-O 3.3Å; N219-M241 WeakPolarHBondContact CB-O 3.14Å; N219-M241 PolarHBondContact ND2-O 3.46Å; N219-M241 PolarHBondContact O-N 2.95Å; N219-G292 WeakPolarHBondContact CB-O 3.26Å; N219-G292 PolarHBondContact N-O 3.49Å; N219-G292 PolarHBondContact OD1-N 3.16Å; N219-L445 HydrophobicContact CB-CD1 4.15Å; N219-L445 HydrophobicContact CB-CD2 4.17Å
220S98.8Very high97.9Very high18 Ų1849.8 Ų49.813%0.12624%0.238CC..EExtended strand (participates in β ladder)trans-141.282.7-175.2-173.40000109.6L445 A449S220-L445 PolarHBondContact OG-O 3.44Å; S220-A449 PolarHBondContact OG-N 3.42Å
221E98.6Very high97.8Very high62 Ų6244.1 Ų44.129%0.2921%0.213SC..EExtended strand (participates in β ladder)trans-158.1160.2172.663.5177.992.700109.9K217 S218 Y223 A239K217-E221 WeakPolarHBondContact CD-OE2 3.35Å; S218-E221 VanDerWaalsContact CB-OE1 3.32Å; S218-E221 WeakPolarHBondContact CB-OE1 3.23Å; S218-E221 PolarHBondContact N-OE1 3.44Å; S218-E221 WeakPolarHBondContact OG-CG 3.45Å; S218-E221 PolarHBondContact OG-OE1 3.21Å; E221-Y223 HydrophobicContact CG-CD1 3.72Å; E221-Y223 HydrophobicContact CG-CE1 3.39Å; E221-Y223 WeakPolarHBondContact O-CE2 3.41Å; E221-Y223 PolarHBondContact O-N 3.32Å; E221-Y223 VanDerWaalsContact O-N 3.16Å; E221-A239 PolarHBondContact N-O 3.03Å; E221-A239 CarbonylContact O-C 3.4Å; E221-A239 WeakPolarHBondContact O-CA 3.4Å
222V98.7Very high97.7Very high59 Ų5945.3 Ų45.336%0.35822%0.215SC..EExtended strand (participates in β ladder)trans-76.8103.8175.8-178.70000110Y225 P237 A239 V450V222-Y225 HydrophobicContact CG1-CE2 4.32Å; V222-P237 HydrophobicContact CG1-CB 4.05Å; V222-P237 HydrophobicContact CG2-CB 4.46Å; V222-A239 HydrophobicContact CG2-CB 4.26Å; V222-V450 HydrophobicContact CG2-CG1 4.4Å
223Y98.6Very high97.6Very high11 Ų1148.1 Ų48.14%0.04324%0.244CC..EExtended strand (participates in β ladder)trans-75.1-31.4179.9-44.3-67.5000112.7K217 S218 N219 E221 I238 M241K217-Y223 HydrophobicContact CB-CD1 4.29Å; K217-Y223 HydrophobicContact CB-CE1 4.23Å; K217-Y223 HydrophobicContact CD-CD1 4.2Å; S218-Y223 WeakPolarHBondContact O-CE1 3.23Å; S218-Y223 PolarHBondContact O-OH 3.21Å; S218-Y223 VanDerWaalsContact O-OH 3.1Å; N219-Y223 PolarHBondContact O-OH 2.64Å; E221-Y223 HydrophobicContact CG-CD1 3.72Å; E221-Y223 HydrophobicContact CG-CE1 3.39Å; E221-Y223 WeakPolarHBondContact O-CE2 3.41Å; E221-Y223 PolarHBondContact O-N 3.32Å; E221-Y223 VanDerWaalsContact O-N 3.16Å; Y223-I238 HydrophobicContact CD2-CB 4.43Å; Y223-I238 HydrophobicContact CD2-CG2 4.04Å; Y223-I238 WeakPolarHBondContact CD2-O 3.22Å; Y223-I238 PolarHBondContact N-O 3Å; Y223-M241 HydrophobicContact CD1-CE 3.63Å; Y223-M241 HydrophobicContact CD2-CE 3.8Å; Y223-M241 HydrophobicContact CD2-CG 4.12Å; Y223-M241 HydrophobicContact CD2-SD 4.34Å; Y223-M241 HydrophobicContact CE1-CE 3.51Å; Y223-M241 HydrophobicContact CE2-CB 3.95Å; Y223-M241 HydrophobicContact CE2-CE 3.72Å; Y223-M241 HydrophobicContact CE2-CG 3.54Å; Y223-M241 HydrophobicContact CE2-SD 4.24Å; Y223-M241 HydrophobicContact CG-CE 3.77Å; Y223-M241 PolarHBondContact OH-N 3.04Å; Y223-M241 VanDerWaalsContact OH-N 3.07Å
224G98.4Very high97.6Very high12 Ų1249.4 Ų49.412%0.12425%0.251CS..EExtended strand (participates in β ladder)trans169.6-168.2-174.500000111.2I238G224-I238 PolarHBondContact O-N 3.12Å
225Y98.7Very high97.5Very high132 Ų13256.3 Ų56.352%0.51828%0.281SS..EExtended strand (participates in β ladder)trans-125.5146.8179.9-61.9-94.5000109.9V222 V236 P237V222-Y225 HydrophobicContact CG1-CE2 4.32Å; Y225-V236 WeakPolarHBondContact CA-O 3.45Å; Y225-P237 HydrophobicContact CD1-CB 4.03Å; Y225-P237 HydrophobicContact CE1-CB 3.81Å; Y225-P237 HydrophobicContact CE1-CG 4.46Å
226T98.6Very high97.5Very high1 Ų150.3 Ų50.31%0.00625%0.253CS..  trans-55.2142.5169.960.40000110.6I76 L172 F231 N234 V236 I238I76-T226 HydrophobicContact CD1-CG2 3.63Å; L172-T226 HydrophobicContact CB-CG2 4.47Å; L172-T226 HydrophobicContact CD2-CG2 4.28Å; L172-T226 CarbonylContact O-C 3.55Å; L172-T226 WeakPolarHBondContact O-CA 3.39Å; T226-F231 HydrophobicContact CG2-CB 4.19Å; T226-F231 HydrophobicContact CG2-CD2 4.21Å; T226-F231 HydrophobicContact CG2-CG 4.32Å; T226-F231 WeakPolarHBondContact OG1-CB 3.49Å; T226-N234 PolarHBondContact OG1-O 3.08Å; T226-V236 HydrophobicContact CG2-CB 4.38Å; T226-V236 PolarHBondContact N-O 2.82Å; T226-V236 PolarHBondContact OG1-N 3.49Å; T226-I238 HydrophobicContact CG2-CD1 4.31Å; T226-I238 HydrophobicContact CG2-CG1 4.14Å
227A97.7Very high97.4Very high14 Ų1449.8 Ų49.812%0.11625%0.25CS..  trans-61.4138.4163.700000108.8L172 Y229 H230 F231L172-A227 PolarHBondContact O-N 3.18Å; A227-Y229 VanDerWaalsContact C-N 3.28Å; A227-Y229 HydrophobicContact CB-CD1 4.05Å; A227-Y229 HydrophobicContact CB-CE1 3.6Å; A227-Y229 HydrophobicContact CB-CE2 4.14Å; A227-Y229 HydrophobicContact CB-CG 4.48Å; A227-Y229 PolarHBondContact O-N 3.15Å; A227-H230 HydrophobicContact CB-CB 4.36Å; A227-H230 PolarHBondContact O-N 2.91Å; A227-F231 PolarHBondContact O-N 3.38Å
228D94.3Very high97.4Very high74 Ų7447.4 Ų47.440%0.39624%0.24SC..G310 helixtrans-59.2-40.1-175.253.86.7000112.1H230 F231 Y232 G233 N234 K235D228-H230 VanDerWaalsContact C-N 3.25Å; D228-H230 PolarHBondContact O-N 2.52Å; D228-F231 CarbonylContact O-C 3.39Å; D228-F231 PolarHBondContact O-N 2.9Å; D228-Y232 PolarHBondContact O-N 3.44Å; D228-G233 WeakPolarHBondContact O-CA 3.28Å; D228-G233 PolarHBondContact O-N 2.92Å; D228-N234 WeakPolarHBondContact CA-O 3.27Å; D228-K235 HydrophobicContact CB-CG 4.38Å
229Y94.7Very high97.5Very high152 Ų15246.6 Ų46.660%0.59623%0.234SC*.G310 helixtrans-70.2-16.1176.760.5-96.5000114.2G174 A227G174-Y229 WeakPolarHBondContact CA-OH 3.46Å; A227-Y229 VanDerWaalsContact C-N 3.28Å; A227-Y229 HydrophobicContact CB-CD1 4.05Å; A227-Y229 HydrophobicContact CB-CE1 3.6Å; A227-Y229 HydrophobicContact CB-CE2 4.14Å; A227-Y229 HydrophobicContact CB-CG 4.48Å; A227-Y229 PolarHBondContact O-N 3.15Å
230H92.6Very high97.4Very high50 Ų5046.6 Ų46.623%0.23123%0.234CC..G310 helixtrans-91.7-18.4172.8-77.9-42.3000113.3W52 K171 A227 D228W52-H230 AromaticContact CZ2-ND1 3.94Å; K171-H230 PolarHBondContact O-CD2 3.01Å; K171-H230 PolarHBondContact O-NE2 2.85Å; A227-H230 HydrophobicContact CB-CB 4.36Å; A227-H230 PolarHBondContact O-N 2.91Å; D228-H230 VanDerWaalsContact C-N 3.25Å; D228-H230 PolarHBondContact O-N 2.52Å
231F96.3Very high97.5Very high0 Ų045.8 Ų45.80%023%0.228CC..THydrogen-bonded Turntrans-128.650179.3-146.9-93.4000112.2M6 I59 P70 I73 I76 T226 A227 D228 G233 N234 V236M6-F231 HydrophobicContact CE-CZ 4.09Å; M6-F231 HydrophobicContact SD-CE2 4.06Å; M6-F231 HydrophobicContact SD-CZ 4.08Å; I59-F231 HydrophobicContact CG2-CD2 4.39Å; I59-F231 HydrophobicContact CG2-CE2 3.79Å; P70-F231 HydrophobicContact CB-CD1 4.04Å; P70-F231 HydrophobicContact CB-CE1 3.93Å; I73-F231 HydrophobicContact CB-CE1 4.28Å; I73-F231 HydrophobicContact CB-CZ 4.4Å; I73-F231 HydrophobicContact CG1-CE1 4.18Å; I73-F231 HydrophobicContact CG1-CZ 4.14Å; I73-F231 HydrophobicContact CG2-CZ 4.47Å; I76-F231 HydrophobicContact CD1-CD2 4.11Å; I76-F231 HydrophobicContact CD1-CE2 3.71Å; I76-F231 HydrophobicContact CD1-CZ 4.11Å; T226-F231 HydrophobicContact CG2-CB 4.19Å; T226-F231 HydrophobicContact CG2-CD2 4.21Å; T226-F231 HydrophobicContact CG2-CG 4.32Å; T226-F231 WeakPolarHBondContact OG1-CB 3.49Å; A227-F231 PolarHBondContact O-N 3.38Å; D228-F231 CarbonylContact O-C 3.39Å; D228-F231 PolarHBondContact O-N 2.9Å; F231-G233 VanDerWaalsContact C-N 3.34Å; F231-G233 PolarHBondContact O-N 2.86Å; F231-N234 HydrophobicContact CD1-CB 4.42Å; F231-N234 WeakPolarHBondContact O-CB 3.24Å; F231-N234 PolarHBondContact O-N 2.88Å; F231-V236 HydrophobicContact CD1-CB 4.17Å; F231-V236 HydrophobicContact CD1-CG2 3.37Å; F231-V236 HydrophobicContact CE1-CB 4.26Å; F231-V236 HydrophobicContact CE1-CG2 3.48Å; F231-V236 VanDerWaalsContact CE1-CG2 3.48Å; F231-V236 HydrophobicContact CG-CG2 4.22Å; F231-V236 HydrophobicContact CZ-CG2 4.39Å
232Y96.7Very high97.5Very high115 Ų11542.8 Ų42.845%0.45122%0.215SC..THydrogen-bonded Turntrans5640.5166.8-44.9-77.8000114.8I59 A60 L63 P70 D228 N234I59-Y232 HydrophobicContact CG2-CE2 4.06Å; A60-Y232 VanDerWaalsContact CA-OH 3.23Å; A60-Y232 WeakPolarHBondContact CA-OH 3.43Å; A60-Y232 VanDerWaalsContact CB-OH 3.24Å; A60-Y232 WeakPolarHBondContact CB-OH 3.46Å; A60-Y232 PolarHBondContact N-OH 2.84Å; L63-Y232 HydrophobicContact CD1-CD2 3.9Å; L63-Y232 HydrophobicContact CD1-CE2 3.45Å; L63-Y232 VanDerWaalsContact CD1-CE2 3.45Å; P70-Y232 HydrophobicContact CB-CD2 4.02Å; P70-Y232 HydrophobicContact CB-CG 4.5Å; P70-Y232 HydrophobicContact CG-CD2 3.66Å; P70-Y232 HydrophobicContact CG-CG 3.86Å; D228-Y232 PolarHBondContact O-N 3.44Å; Y232-N234 PolarHBondContact O-ND2 3.44Å; Y232-N234 VanDerWaalsContact O-ND2 3.12Å
233G96.6Very high97.5Very high60 Ų6040 Ų4062%0.61920%0.198SC*.THydrogen-bonded Turntrans86.34.9-179.500000114.8D228 F231D228-G233 WeakPolarHBondContact O-CA 3.28Å; D228-G233 PolarHBondContact O-N 2.92Å; F231-G233 VanDerWaalsContact C-N 3.34Å; F231-G233 PolarHBondContact O-N 2.86Å
234N96.9Very high97.4Very high47 Ų4740.4 Ų40.425%0.25120%0.2SC..  trans-115.8148.3-176.3-63.6-85.1000111.8T226 D228 F231 Y232 V236T226-N234 PolarHBondContact OG1-O 3.08Å; D228-N234 WeakPolarHBondContact CA-O 3.27Å; F231-N234 HydrophobicContact CD1-CB 4.42Å; F231-N234 WeakPolarHBondContact O-CB 3.24Å; F231-N234 PolarHBondContact O-N 2.88Å; Y232-N234 PolarHBondContact O-ND2 3.44Å; Y232-N234 VanDerWaalsContact O-ND2 3.12Å; N234-V236 HydrophobicContact CB-CG2 4.26Å
235K97.3Very high97.3Very high147 Ų14740.2 Ų40.264%0.63920%0.196SC*.  trans-105.197.1172.2-67.5-170.8176-1720108.7D228D228-K235 HydrophobicContact CB-CG 4.38Å
236V98.2Very high97.3Very high5 Ų533.9 Ų33.93%0.0317%0.172CC..  trans-98.3134-177.5179.70000109.1I73 I76 Y225 T226 F231 N234 I238I73-V236 HydrophobicContact CB-CG1 4.24Å; I73-V236 HydrophobicContact CG2-CG1 3.81Å; I76-V236 HydrophobicContact CD1-CB 4.08Å; I76-V236 HydrophobicContact CD1-CG1 3.78Å; I76-V236 HydrophobicContact CG1-CG1 3.75Å; Y225-V236 WeakPolarHBondContact CA-O 3.45Å; T226-V236 HydrophobicContact CG2-CB 4.38Å; T226-V236 PolarHBondContact N-O 2.82Å; T226-V236 PolarHBondContact OG1-N 3.49Å; F231-V236 HydrophobicContact CD1-CB 4.17Å; F231-V236 HydrophobicContact CD1-CG2 3.37Å; F231-V236 HydrophobicContact CE1-CB 4.26Å; F231-V236 HydrophobicContact CE1-CG2 3.48Å; F231-V236 VanDerWaalsContact CE1-CG2 3.48Å; F231-V236 HydrophobicContact CG-CG2 4.22Å; F231-V236 HydrophobicContact CZ-CG2 4.39Å; N234-V236 HydrophobicContact CB-CG2 4.26Å; V236-I238 PolarHBondContact O-N 3.35Å
237P98.6Very high97.3Very high20 Ų2033.9 Ų33.913%0.1317%0.171CC..EExtended strand (participates in β ladder)trans-67.6133.1179.727.2-33.1000110.7E74 G75 I76 V222 Y225 V450E74-P237 WeakPolarHBondContact O-CD 3.24Å; E74-P237 WeakPolarHBondContact O-CG 3.38Å; G75-P237 WeakPolarHBondContact CA-O 3.39Å; I76-P237 PolarHBondContact N-O 2.92Å; V222-P237 HydrophobicContact CG1-CB 4.05Å; V222-P237 HydrophobicContact CG2-CB 4.46Å; Y225-P237 HydrophobicContact CD1-CB 4.03Å; Y225-P237 HydrophobicContact CE1-CB 3.81Å; Y225-P237 HydrophobicContact CE1-CG 4.46Å; P237-V450 HydrophobicContact CB-CG1 4.26Å; P237-V450 HydrophobicContact CG-CG1 3.88Å
238I98.9Very high97.2Very high0 Ų033.2 Ų33.20%017%0.166CC..EExtended strand (participates in β ladder)trans-93.2113.7168.6-50.2173.2000105.7I78 V169 L172 T173 Y223 G224 T226 V236I78-I238 HydrophobicContact CD1-CG2 3.63Å; I78-I238 HydrophobicContact CG1-CG2 4.22Å; V169-I238 HydrophobicContact CG1-CD1 4.41Å; V169-I238 HydrophobicContact CG2-CG2 4.26Å; L172-I238 HydrophobicContact CB-CD1 3.74Å; L172-I238 HydrophobicContact CD1-CD1 4.18Å; T173-I238 HydrophobicContact CG2-CD1 3.76Å; Y223-I238 HydrophobicContact CD2-CB 4.43Å; Y223-I238 HydrophobicContact CD2-CG2 4.04Å; Y223-I238 WeakPolarHBondContact CD2-O 3.22Å; Y223-I238 PolarHBondContact N-O 3Å; G224-I238 PolarHBondContact O-N 3.12Å; T226-I238 HydrophobicContact CG2-CD1 4.31Å; T226-I238 HydrophobicContact CG2-CG1 4.14Å; V236-I238 PolarHBondContact O-N 3.35Å
239A98.8Very high97.4Very high0 Ų029.7 Ų29.70%015%0.147CC..EExtended strand (participates in β ladder)trans-135.9-4.9-158.900000115.4I76 E221 V222 A446 A449 V450I76-A239 PolarHBondContact O-N 2.87Å; E221-A239 PolarHBondContact N-O 3.03Å; E221-A239 CarbonylContact O-C 3.4Å; E221-A239 WeakPolarHBondContact O-CA 3.4Å; V222-A239 HydrophobicContact CG2-CB 4.26Å; A239-A446 HydrophobicContact CB-CB 4.23Å; A239-A449 HydrophobicContact CB-CB 3.83Å; A239-A449 WeakPolarHBondContact O-CB 3.3Å; A239-V450 HydrophobicContact CB-CG1 3.57Å
240G98.8Very high97.5Very high0 Ų022.5 Ų22.50%012%0.119CC..EExtended strand (participates in β ladder)trans-136135.5173.500000110.7I76 G77 I78 N219I76-G240 PolarHBondContact O-N 3.45Å; G77-G240 CarbonylContact C-O 3.56Å; G77-G240 WeakPolarHBondContact CA-O 3.29Å; I78-G240 PolarHBondContact N-O 2.86Å; N219-G240 WeakPolarHBondContact O-CA 3.39Å
241M98.9Very high97.7Very high0 Ų020.4 Ų20.40%011%0.111CC..EExtended strand (participates in β ladder)trans-143.5133.4174.1-79.2-167.1-57.200109.7I78 D165 V169 V179 D181 N219 Y223I78-M241 HydrophobicContact CB-CG 4.31Å; I78-M241 WeakPolarHBondContact O-CA 3.46Å; D165-M241 HydrophobicContact CB-SD 4.14Å; V169-M241 HydrophobicContact CG2-SD 3.56Å; V169-M241 VanDerWaalsContact CG2-SD 3.56Å; V179-M241 HydrophobicContact CG1-CE 3.82Å; V179-M241 HydrophobicContact CG2-CE 4.2Å; D181-M241 HydrophobicContact CB-CB 3.78Å; D181-M241 HydrophobicContact CB-CE 4.33Å; N219-M241 WeakPolarHBondContact CA-O 3.3Å; N219-M241 VanDerWaalsContact CB-O 3.3Å; N219-M241 WeakPolarHBondContact CB-O 3.14Å; N219-M241 PolarHBondContact ND2-O 3.46Å; N219-M241 PolarHBondContact O-N 2.95Å; Y223-M241 HydrophobicContact CD1-CE 3.63Å; Y223-M241 HydrophobicContact CD2-CE 3.8Å; Y223-M241 HydrophobicContact CD2-CG 4.12Å; Y223-M241 HydrophobicContact CD2-SD 4.34Å; Y223-M241 HydrophobicContact CE1-CE 3.51Å; Y223-M241 HydrophobicContact CE2-CB 3.95Å; Y223-M241 HydrophobicContact CE2-CE 3.72Å; Y223-M241 HydrophobicContact CE2-CG 3.54Å; Y223-M241 HydrophobicContact CE2-SD 4.24Å; Y223-M241 HydrophobicContact CG-CE 3.77Å; Y223-M241 PolarHBondContact OH-N 3.04Å; Y223-M241 VanDerWaalsContact OH-N 3.07Å
242A98.9Very high97.6Very high0 Ų021.1 Ų21.10%011%0.114CC..EExtended strand (participates in β ladder)trans-159.7149.4170.300000110.1I78 T79 T183 A247 V442 L445I78-A242 PolarHBondContact O-N 3.37Å; T79-A242 VanDerWaalsContact CA-O 3.27Å; T79-A242 WeakPolarHBondContact CA-O 3.39Å; T79-A242 PolarHBondContact OG1-O 2.67Å; T183-A242 WeakPolarHBondContact OG1-CA 3.35Å; A242-A247 HydrophobicContact CB-CB 4.02Å; A242-V442 HydrophobicContact CB-CG1 4.07Å; A242-L445 HydrophobicContact CB-CD1 3.81Å
243G98.6Very high97.6Very high0 Ų016.4 Ų16.40%010%0.097CC..EExtended strand (participates in β ladder)trans-60.2144.5164.400000110.6R82 T183 N184 Q245 Q246 A247R82-G243 VanDerWaalsContact CG-CA 3.47Å; T183-G243 PolarHBondContact OG1-N 3.19Å; N184-G243 PolarHBondContact ND2-N 2.98Å; N184-G243 VanDerWaalsContact ND2-N 3.2Å; G243-Q245 VanDerWaalsContact C-N 3.31Å; G243-Q245 PolarHBondContact O-N 2.92Å; G243-Q245 VanDerWaalsContact O-N 3.12Å; G243-Q246 CarbonylContact O-C 3.53Å; G243-Q246 WeakPolarHBondContact O-CA 3.48Å; G243-Q246 WeakPolarHBondContact O-CB 3.29Å; G243-Q246 PolarHBondContact O-N 3.49Å; G243-A247 PolarHBondContact O-N 3.5Å
244D96.4Very high97.5Very high19 Ų1913.6 Ų13.610%0.1027%0.068CC..Hα-helixtrans-48.3-44.4-172.359.5-1.2000115.6T79 N80 R82 Q246 A247 A248 T438T79-D244 WeakPolarHBondContact OG1-CA 3.48Å; T79-D244 PolarHBondContact OG1-N 2.99Å; N80-D244 VanDerWaalsContact O-CB 3.25Å; N80-D244 WeakPolarHBondContact O-CB 3.3Å; N80-D244 VanDerWaalsContact O-CG 3.26Å; N80-D244 PolarHBondContact O-N 3.17Å; R82-D244 IonicContact NE-OD1 3.74Å; R82-D244 PolarHBondContact NE-OD1 2.85Å; D244-Q246 VanDerWaalsContact C-N 3.34Å; D244-Q246 PolarHBondContact O-N 2.77Å; D244-A247 WeakPolarHBondContact O-CB 3.5Å; D244-A247 PolarHBondContact O-N 2.74Å; D244-A248 WeakPolarHBondContact O-CB 3.48Å; D244-A248 PolarHBondContact O-N 3.03Å; D244-T438 HydrophobicContact CB-CG2 3.74Å; D244-T438 WeakPolarHBondContact O-CG2 3.28Å
245Q96.9Very high97.5Very high8 Ų812.4 Ų12.44%0.0376%0.06CC..Hα-helixtrans-71.9-31.4-178-52.4-46.5-42.900113R82 G243 L249 K261 F269 V271R82-Q245 VanDerWaalsContact CZ-CG 3.42Å; R82-Q245 VanDerWaalsContact NH2-CG 3.3Å; G243-Q245 VanDerWaalsContact C-N 3.31Å; G243-Q245 PolarHBondContact O-N 2.92Å; G243-Q245 VanDerWaalsContact O-N 3.12Å; Q245-L249 PolarHBondContact O-N 2.71Å; Q245-L249 VanDerWaalsContact O-N 3.15Å; Q245-K261 WeakPolarHBondContact O-CE 3.41Å; Q245-K261 PolarHBondContact O-NZ 2.7Å; Q245-K261 VanDerWaalsContact O-NZ 3.13Å; Q245-K261 VanDerWaalsContact OE1-NZ 3.09Å; Q245-F269 HydrophobicContact CB-CB 4.27Å; Q245-F269 HydrophobicContact CG-CB 3.63Å; Q245-F269 HydrophobicContact CG-CD1 3.99Å; Q245-F269 HydrophobicContact CG-CD2 3.9Å; Q245-F269 HydrophobicContact CG-CG 3.58Å; Q245-V271 HydrophobicContact CB-CG2 4.1Å
246Q98.5Very high97.4Very high0 Ų09.6 Ų9.60%05%0.052CC..Hα-helixtrans-75.9-37.7173.1-79.289.3-26.400111.5R82 T183 G243 D244 A248 L249 V250 T288 I289 G290R82-Q246 VanDerWaalsContact CD-OE1 3.25Å; T183-Q246 HydrophobicContact CG2-CB 3.82Å; T183-Q246 HydrophobicContact CG2-CG 3.69Å; G243-Q246 CarbonylContact O-C 3.53Å; G243-Q246 WeakPolarHBondContact O-CA 3.48Å; G243-Q246 WeakPolarHBondContact O-CB 3.29Å; G243-Q246 PolarHBondContact O-N 3.49Å; D244-Q246 VanDerWaalsContact C-N 3.34Å; D244-Q246 PolarHBondContact O-N 2.77Å; Q246-A248 VanDerWaalsContact C-N 3.31Å; Q246-A248 PolarHBondContact O-N 2.95Å; Q246-L249 VanDerWaalsContact O-CB 3.31Å; Q246-L249 WeakPolarHBondContact O-CB 3.02Å; Q246-L249 PolarHBondContact O-N 3.33Å; Q246-L249 VanDerWaalsContact O-N 3.12Å; Q246-V250 PolarHBondContact O-N 2.9Å; Q246-T288 PolarHBondContact NE2-OG1 3.07Å; Q246-I289 WeakPolarHBondContact CG-O 3.47Å; Q246-I289 PolarHBondContact NE2-O 3.05Å; Q246-G290 VanDerWaalsContact CB-O 3.26Å; Q246-G290 WeakPolarHBondContact CB-O 3.22Å; Q246-G290 WeakPolarHBondContact CG-O 3.37Å
247A98.2Very high97.2Very high0 Ų015.8 Ų15.80%08%0.079CC..Hα-helixtrans-57.9-46.2170.200000110.6T79 A242 G243 D244 L249 V250 G251 T438 G441 V442T79-A247 WeakPolarHBondContact OG1-CB 3.39Å; A242-A247 HydrophobicContact CB-CB 4.02Å; G243-A247 PolarHBondContact O-N 3.5Å; D244-A247 WeakPolarHBondContact O-CB 3.5Å; D244-A247 PolarHBondContact O-N 2.74Å; A247-L249 VanDerWaalsContact C-N 3.3Å; A247-L249 PolarHBondContact O-N 2.85Å; A247-V250 WeakPolarHBondContact O-CB 3.16Å; A247-V250 PolarHBondContact O-N 3.21Å; A247-V250 VanDerWaalsContact O-N 3.13Å; A247-G251 PolarHBondContact O-N 3.4Å; A247-T438 HydrophobicContact CB-CG2 4.16Å; A247-T438 WeakPolarHBondContact CB-O 3.26Å; A247-G441 WeakPolarHBondContact O-CA 3.44Å; A247-V442 HydrophobicContact CB-CG1 3.84Å
248A96.9Very high97Very high0 Ų015.7 Ų15.70%08%0.082CC..Hα-helixtrans-62.1-34.3175.100000112.9D244 Q246 G251 Q252 K261D244-A248 WeakPolarHBondContact O-CB 3.48Å; D244-A248 PolarHBondContact O-N 3.03Å; Q246-A248 VanDerWaalsContact C-N 3.31Å; Q246-A248 PolarHBondContact O-N 2.95Å; A248-G251 PolarHBondContact O-N 3.07Å; A248-Q252 VanDerWaalsContact O-CB 3.32Å; A248-Q252 WeakPolarHBondContact O-CB 3.43Å; A248-Q252 VanDerWaalsContact O-CG 3.23Å; A248-Q252 WeakPolarHBondContact O-CG 3.49Å; A248-Q252 PolarHBondContact O-N 3.45Å; A248-K261 HydrophobicContact CB-CD 4.44Å
249L97.6Very high96.9Very high0 Ų017.8 Ų17.80%09%0.092CC..Hα-helixtrans-61.1-45.2172.6-173.874.1000111.3Q245 Q246 A247 Q252 A254 K261 V271 N273 Y291Q245-L249 PolarHBondContact O-N 2.71Å; Q245-L249 VanDerWaalsContact O-N 3.15Å; Q246-L249 VanDerWaalsContact O-CB 3.31Å; Q246-L249 WeakPolarHBondContact O-CB 3.02Å; Q246-L249 PolarHBondContact O-N 3.33Å; Q246-L249 VanDerWaalsContact O-N 3.12Å; A247-L249 VanDerWaalsContact C-N 3.3Å; A247-L249 PolarHBondContact O-N 2.85Å; L249-Q252 PolarHBondContact O-N 2.75Å; L249-A254 HydrophobicContact CD1-CB 3.49Å; L249-A254 VanDerWaalsContact CD1-CB 3.49Å; L249-A254 HydrophobicContact CG-CB 3.95Å; L249-A254 WeakPolarHBondContact O-CB 3.32Å; L249-A254 PolarHBondContact O-N 2.56Å; L249-A254 VanDerWaalsContact O-N 3.09Å; L249-K261 HydrophobicContact CB-CG 4.49Å; L249-K261 HydrophobicContact CD1-CG 3.9Å; L249-V271 HydrophobicContact CD1-CB 4.31Å; L249-V271 HydrophobicContact CD1-CG1 4.15Å; L249-V271 HydrophobicContact CD2-CG1 3.95Å; L249-V271 HydrophobicContact CG-CG1 4.45Å; L249-N273 HydrophobicContact CD2-CB 4.44Å; L249-Y291 HydrophobicContact CD2-CE1 4.26Å
250V97.4Very high96.8Very high1 Ų118 Ų181%0.0069%0.094CC..Hα-helixtrans-65.1-43.7175176.30000111.3Q246 A247 Q252 L253 F255 Y291 L445Q246-V250 PolarHBondContact O-N 2.9Å; A247-V250 WeakPolarHBondContact O-CB 3.16Å; A247-V250 PolarHBondContact O-N 3.21Å; A247-V250 VanDerWaalsContact O-N 3.13Å; V250-Q252 VanDerWaalsContact C-N 3.28Å; V250-Q252 PolarHBondContact O-N 2.97Å; V250-L253 WeakPolarHBondContact O-CA 3.3Å; V250-L253 PolarHBondContact O-N 3.08Å; V250-F255 HydrophobicContact CG1-CE1 4.09Å; V250-F255 HydrophobicContact CG1-CZ 3.84Å; V250-Y291 HydrophobicContact CG2-CD1 3.63Å; V250-Y291 HydrophobicContact CG2-CE1 4.17Å; V250-Y291 HydrophobicContact CG2-CG 4.17Å; V250-L445 HydrophobicContact CG1-CD2 4.3Å; V250-L445 HydrophobicContact CG1-CG 4.2Å; V250-L445 HydrophobicContact CG2-CD2 4.48Å
251G96.1Very high96.7Very high7 Ų718 Ų187%0.0729%0.094CC..Hα-helixtrans-66.5-27.2179.100000114A247 A248 L253 T437A247-G251 PolarHBondContact O-N 3.4Å; A248-G251 PolarHBondContact O-N 3.07Å; G251-L253 PolarHBondContact O-N 2.96Å; G251-T437 WeakPolarHBondContact CA-O 3.46Å
252Q95.2Very high96.7Very high14 Ų1418 Ų187%0.0659%0.094CC..THydrogen-bonded Turntrans-77.43168.9-75.3-79.312.100113.3A248 L249 V250 A254 K261 R406 V407 D408 T437A248-Q252 VanDerWaalsContact O-CB 3.32Å; A248-Q252 WeakPolarHBondContact O-CB 3.43Å; A248-Q252 VanDerWaalsContact O-CG 3.23Å; A248-Q252 WeakPolarHBondContact O-CG 3.49Å; A248-Q252 PolarHBondContact O-N 3.45Å; L249-Q252 PolarHBondContact O-N 2.75Å; V250-Q252 VanDerWaalsContact C-N 3.28Å; V250-Q252 PolarHBondContact O-N 2.97Å; Q252-A254 HydrophobicContact CB-CB 4.49Å; Q252-A254 PolarHBondContact O-N 2.94Å; Q252-K261 HydrophobicContact CB-CB 4.34Å; Q252-K261 HydrophobicContact CG-CB 3.96Å; Q252-K261 HydrophobicContact CG-CG 4.35Å; Q252-R406 PolarHBondContact O-NH1 3.32Å; Q252-V407 PolarHBondContact NE2-O 2.8Å; Q252-D408 WeakPolarHBondContact CG-OD2 3.47Å; Q252-D408 PolarHBondContact NE2-OD2 2.72Å; Q252-T437 HydrophobicContact CG-CG2 4.18Å
253L95.5Very high96.6Very high16 Ų1618.5 Ų18.58%0.08410%0.097CC..THydrogen-bonded Turntrans54.632.4-176.4-53.9172.4000112.3V250 G251 F255 Y444 I459 A463V250-L253 WeakPolarHBondContact O-CA 3.3Å; V250-L253 PolarHBondContact O-N 3.08Å; G251-L253 PolarHBondContact O-N 2.96Å; L253-F255 HydrophobicContact CB-CD2 4.29Å; L253-F255 HydrophobicContact CB-CE2 4.16Å; L253-F255 HydrophobicContact CD2-CE2 3.77Å; L253-F255 PolarHBondContact O-N 2.9Å; L253-Y444 HydrophobicContact CD2-CD2 4.11Å; L253-Y444 HydrophobicContact CD2-CE2 3.66Å; L253-I459 HydrophobicContact CD2-CD1 4.15Å; L253-I459 HydrophobicContact CD2-CG1 4.2Å; L253-A463 HydrophobicContact CD1-CB 3.64Å
254A95.5Very high96.3Very high1 Ų118.5 Ų18.51%0.00810%0.097CC..  trans-82.360.3-177.400000111.6L249 Q252 M259 N273L249-A254 HydrophobicContact CD1-CB 3.49Å; L249-A254 VanDerWaalsContact CD1-CB 3.49Å; L249-A254 HydrophobicContact CG-CB 3.95Å; L249-A254 WeakPolarHBondContact O-CB 3.32Å; L249-A254 PolarHBondContact O-N 2.56Å; L249-A254 VanDerWaalsContact O-N 3.09Å; Q252-A254 HydrophobicContact CB-CB 4.49Å; Q252-A254 PolarHBondContact O-N 2.94Å; A254-M259 HydrophobicContact CB-CB 3.77Å; A254-M259 HydrophobicContact CB-CE 4.28Å; A254-M259 HydrophobicContact CB-SD 4.45Å; A254-N273 PolarHBondContact O-ND2 2.95Å
255F95.8Very high96Very high22 Ų2218.9 Ų18.910%0.09611%0.105CC..  trans-84-21.9-176.6-64.8-70.7000113.9V250 L253 N273 Y291 I293 I456 I459V250-F255 HydrophobicContact CG1-CE1 4.09Å; V250-F255 HydrophobicContact CG1-CZ 3.84Å; L253-F255 HydrophobicContact CB-CD2 4.29Å; L253-F255 HydrophobicContact CB-CE2 4.16Å; L253-F255 HydrophobicContact CD2-CE2 3.77Å; L253-F255 PolarHBondContact O-N 2.9Å; F255-N273 PolarHBondContact O-ND2 3.2Å; F255-Y291 WeakPolarHBondContact CA-OH 3.48Å; F255-Y291 HydrophobicContact CD1-CE1 4.44Å; F255-Y291 HydrophobicContact CD1-CE2 4.33Å; F255-Y291 AromaticContact CD1-CZ 3.85Å; F255-Y291 PolarHBondContact O-OH 2.73Å; F255-I293 HydrophobicContact CE1-CD1 4.44Å; F255-I456 HydrophobicContact CB-CG2 4.43Å; F255-I456 HydrophobicContact CD1-CD1 3.96Å; F255-I456 HydrophobicContact CD1-CG2 4.25Å; F255-I456 HydrophobicContact CD2-CG2 3.54Å; F255-I456 HydrophobicContact CE1-CD1 4.05Å; F255-I456 HydrophobicContact CE1-CG1 4.34Å; F255-I456 HydrophobicContact CE1-CG2 4.42Å; F255-I456 HydrophobicContact CE2-CG2 3.72Å; F255-I456 HydrophobicContact CG-CD1 4.48Å; F255-I456 HydrophobicContact CG-CG2 3.81Å; F255-I456 HydrophobicContact CZ-CG1 4.44Å; F255-I456 HydrophobicContact CZ-CG2 4.17Å; F255-I459 HydrophobicContact CE2-CD1 3.69Å; F255-I459 HydrophobicContact CE2-CG1 4.44Å; F255-I459 HydrophobicContact CZ-CD1 3.58Å
256D94.8Very high95.5Very high88 Ų8820.1 Ų20.147%0.47111%0.113SC..SBendtrans-92.9143.8-176.2-56.5-59.7000111.3G258 M259 K460D256-G258 PolarHBondContact O-N 3.35Å; D256-M259 HydrophobicContact CB-CG 4.18Å; D256-M259 HydrophobicContact CB-SD 3.75Å; D256-M259 WeakPolarHBondContact O-CB 3.2Å; D256-M259 VanDerWaalsContact O-CG 3.3Å; D256-M259 WeakPolarHBondContact O-CG 3.4Å; D256-M259 PolarHBondContact O-N 3.48Å; D256-K460 IonicContact OD1-NZ 3.11Å; D256-K460 IonicContact OD2-NZ 2.72Å; D256-K460 PolarHBondContact OD2-NZ 2.92Å; D256-K460 VanDerWaalsContact OD2-NZ 3.11Å
257K95.2Very high95.1Very high135 Ų13520.1 Ų20.159%0.58711%0.114SC*.THydrogen-bonded Turntrans-56.3134.7178.8177.4174.1-177.91650110.9M259 T274K257-M259 VanDerWaalsContact C-N 3.33Å; K257-T274 WeakPolarHBondContact CD-O 3.11Å; K257-T274 WeakPolarHBondContact CE-O 3.41Å
258G94.6Very high94.9Very high19 Ų1920.2 Ų20.220%0.19611%0.114CC..THydrogen-bonded Turntrans87.6-6.2-179.800000114.2D256 V260 N273D256-G258 PolarHBondContact O-N 3.35Å; G258-V260 WeakPolarHBondContact O-CG2 3.3Å; G258-V260 PolarHBondContact O-N 3.17Å; G258-N273 PolarHBondContact N-O 2.83Å
259M96Very high94.9Very high43 Ų4320.8 Ų20.821%0.21212%0.117CC..  trans-69.3131171-66.6-176.875.600110.2A254 D256 K257 M272 N273A254-M259 HydrophobicContact CB-CB 3.77Å; A254-M259 HydrophobicContact CB-CE 4.28Å; A254-M259 HydrophobicContact CB-SD 4.45Å; D256-M259 HydrophobicContact CB-CG 4.18Å; D256-M259 HydrophobicContact CB-SD 3.75Å; D256-M259 WeakPolarHBondContact O-CB 3.2Å; D256-M259 VanDerWaalsContact O-CG 3.3Å; D256-M259 WeakPolarHBondContact O-CG 3.4Å; D256-M259 PolarHBondContact O-N 3.48Å; K257-M259 VanDerWaalsContact C-N 3.33Å; M259-M272 WeakPolarHBondContact O-CA 3.3Å; M259-N273 PolarHBondContact O-N 3.2Å
260V97Very high94.9Very high5 Ų520.8 Ų20.83%0.0312%0.117CC..EExtended strand (participates in β ladder)trans-124137.1-176.1-168.90000110.4G258 I270 V271 M272 M394 I402 L405 R406G258-V260 WeakPolarHBondContact O-CG2 3.3Å; G258-V260 PolarHBondContact O-N 3.17Å; V260-I270 HydrophobicContact CG1-CG2 3.58Å; V260-V271 WeakPolarHBondContact CA-O 3.13Å; V260-M272 HydrophobicContact CG1-CB 4.44Å; V260-M272 HydrophobicContact CG2-CB 3.83Å; V260-M272 HydrophobicContact CG2-CE 3.44Å; V260-M272 VanDerWaalsContact CG2-CE 3.44Å; V260-M272 HydrophobicContact CG2-CG 3.86Å; V260-M394 HydrophobicContact CG1-SD 4.32Å; V260-I402 HydrophobicContact CB-CG2 4.39Å; V260-I402 HydrophobicContact CG2-CD1 3.94Å; V260-I402 HydrophobicContact CG2-CG1 3.81Å; V260-I402 HydrophobicContact CG2-CG2 4.06Å; V260-L405 HydrophobicContact CB-CD1 4.34Å; V260-L405 HydrophobicContact CG1-CD1 3.81Å; V260-R406 PolarHBondContact O-N 3.47Å; V260-R406 VanDerWaalsContact O-N 3.14Å
261K97.4Very high94.9Very high0 Ų020.7 Ų20.70%012%0.116CC..EExtended strand (participates in β ladder)trans-124157.2168.67185.2174.3175.40111.7Q245 A248 L249 Q252 T263 F269 I270 V271 R406Q245-K261 WeakPolarHBondContact O-CE 3.41Å; Q245-K261 PolarHBondContact O-NZ 2.7Å; Q245-K261 VanDerWaalsContact O-NZ 3.13Å; Q245-K261 VanDerWaalsContact OE1-NZ 3.09Å; A248-K261 HydrophobicContact CB-CD 4.44Å; L249-K261 HydrophobicContact CB-CG 4.49Å; L249-K261 HydrophobicContact CD1-CG 3.9Å; Q252-K261 HydrophobicContact CB-CB 4.34Å; Q252-K261 HydrophobicContact CG-CB 3.96Å; Q252-K261 HydrophobicContact CG-CG 4.35Å; K261-T263 PolarHBondContact NZ-OG1 2.8Å; K261-F269 PolarHBondContact NZ-O 2.86Å; K261-I270 CarbonylContact O-C 3.22Å; K261-I270 VanDerWaalsContact O-CA 3.27Å; K261-I270 WeakPolarHBondContact O-CA 3.18Å; K261-V271 PolarHBondContact N-O 2.83Å; K261-V271 PolarHBondContact O-N 3.32Å; K261-R406 CarbonylContact C-O 3.59Å; K261-R406 WeakPolarHBondContact CA-O 3.18Å; K261-R406 HydrophobicContact CB-CB 4.34Å
262N97.9Very high95Very high0 Ų020.5 Ų20.50%011%0.113CC..EExtended strand (participates in β ladder)trans-129.9125.4164.8-172.916.7000111Y264 F269 I270 T387 L405 R406 V407 D408N262-Y264 HydrophobicContact CB-CE2 4.26Å; N262-Y264 WeakPolarHBondContact ND2-CE1 3.4Å; N262-Y264 WeakPolarHBondContact ND2-CE2 3.37Å; N262-Y264 PolarHBondContact ND2-OH 3.14Å; N262-F269 WeakPolarHBondContact CA-O 3.43Å; N262-F269 PolarHBondContact OD1-N 3.06Å; N262-F269 PolarHBondContact OD1-O 3.26Å; N262-I270 HydrophobicContact CB-CG1 4.07Å; N262-T387 WeakPolarHBondContact ND2-CG2 3.44Å; N262-T387 PolarHBondContact ND2-OG1 3Å; N262-T387 VanDerWaalsContact ND2-OG1 3.15Å; N262-L405 HydrophobicContact CB-CD1 4.08Å; N262-L405 HydrophobicContact CB-CD2 4.36Å; N262-L405 HydrophobicContact CB-CG 4.46Å; N262-R406 PolarHBondContact N-O 3.16Å; N262-V407 HydrophobicContact CB-CG1 4.38Å; N262-V407 VanDerWaalsContact O-CA 3.27Å; N262-V407 WeakPolarHBondContact O-CA 3.3Å; N262-D408 PolarHBondContact O-N 2.92Å; N262-D408 VanDerWaalsContact O-N 3.1Å
263T96.4Very high95.2Very high10 Ų1019.9 Ų19.96%0.06111%0.111CC..EExtended strand (participates in β ladder)trans-97.4111.1176.2-63.40000110.1K261 G265 A268 F269 D408K261-T263 PolarHBondContact NZ-OG1 2.8Å; T263-G265 PolarHBondContact O-N 2.79Å; T263-A268 VanDerWaalsContact O-CA 3.3Å; T263-A268 WeakPolarHBondContact O-CA 3.27Å; T263-F269 PolarHBondContact N-O 2.79Å; T263-F269 PolarHBondContact O-N 3.42Å; T263-D408 WeakPolarHBondContact CA-OD1 3.2Å; T263-D408 WeakPolarHBondContact CB-OD1 3.38Å; T263-D408 WeakPolarHBondContact CG2-OD1 3.27Å; T263-D408 PolarHBondContact OG1-OD1 2.6Å
264Y94Very high95.3Very high0 Ų019.1 Ų19.10%011%0.107CC..EExtended strand (participates in β ladder)trans-88.382.1175.4-64.7-88.3000111.4N262 A268 T387 V407 D408 G409 G410 A411 L417 L418 Q421N262-Y264 HydrophobicContact CB-CE2 4.26Å; N262-Y264 WeakPolarHBondContact ND2-CE1 3.4Å; N262-Y264 WeakPolarHBondContact ND2-CE2 3.37Å; N262-Y264 PolarHBondContact ND2-OH 3.14Å; Y264-A268 HydrophobicContact CD1-CB 4.13Å; Y264-A268 HydrophobicContact CE1-CB 4.42Å; Y264-T387 PolarHBondContact OH-OG1 2.81Å; Y264-V407 HydrophobicContact CD2-CB 4.2Å; Y264-V407 HydrophobicContact CD2-CG1 4.46Å; Y264-V407 HydrophobicContact CE2-CB 3.93Å; Y264-V407 HydrophobicContact CE2-CG1 3.71Å; Y264-D408 PolarHBondContact N-O 2.95Å; Y264-G409 CarbonylContact O-C 3.6Å; Y264-G409 VanDerWaalsContact O-C 3.29Å; Y264-G410 PolarHBondContact O-N 3.48Å; Y264-G410 VanDerWaalsContact O-N 3.11Å; Y264-A411 PolarHBondContact O-N 2.77Å; Y264-L417 HydrophobicContact CD1-CD2 4.4Å; Y264-L418 HydrophobicContact CE2-CD2 4.29Å; Y264-Q421 VanDerWaalsContact OH-CD 3.29Å; Y264-Q421 WeakPolarHBondContact OH-CG 3.49Å; Y264-Q421 PolarHBondContact OH-OE1 3.27Å
265G89.4Confident95.3Very high28 Ų2819.8 Ų19.829%0.28911%0.114SC..SBendtrans-103.4-138.7173.200000112.2T263 G267 G309T263-G265 PolarHBondContact O-N 2.79Å; G265-G267 VanDerWaalsContact C-N 3.34Å; G265-G267 CarbonylContact C-O 3.56Å; G265-G267 WeakPolarHBondContact CA-O 3.31Å; G265-G267 PolarHBondContact N-O 2.95Å; G265-G309 WeakPolarHBondContact O-CA 3.5Å; G265-G309 PolarHBondContact O-N 3.46Å
266T85.9Confident95.4Very high33 Ų3323.9 Ų23.920%0.20213%0.133CC..SBendtrans-58.6-47.7171.1-57.10000110.8A308 G309 S310T266-A308 PolarHBondContact O-N 3.35Å; T266-G309 PolarHBondContact O-N 3.19Å; T266-S310 PolarHBondContact O-N 3.05Å; T266-S310 PolarHBondContact O-OG 3.36Å
267G90.7Very high95.5Very high1 Ų126.3 Ų26.31%0.0114%0.142CC..SBendtrans-104.3178.516200000111.2G265 V305G265-G267 VanDerWaalsContact C-N 3.34Å; G265-G267 CarbonylContact C-O 3.56Å; G265-G267 WeakPolarHBondContact CA-O 3.31Å; G265-G267 PolarHBondContact N-O 2.95Å; G267-V305 CarbonylContact C-O 3.58Å; G267-V305 WeakPolarHBondContact CA-O 3.41Å
268A94.7Very high95.5Very high1 Ų121.5 Ų21.51%0.00812%0.124CC..EExtended strand (participates in β ladder)trans-114.6131.6168.400000109.9T263 Y264 V305 A308T263-A268 VanDerWaalsContact O-CA 3.3Å; T263-A268 WeakPolarHBondContact O-CA 3.27Å; Y264-A268 HydrophobicContact CD1-CB 4.13Å; Y264-A268 HydrophobicContact CE1-CB 4.42Å; A268-V305 HydrophobicContact CB-CB 4.05Å; A268-V305 HydrophobicContact CB-CG1 4.49Å; A268-V305 PolarHBondContact N-O 2.89Å; A268-V305 WeakPolarHBondContact O-CA 3.47Å; A268-V305 VanDerWaalsContact O-CB 3.32Å; A268-V305 WeakPolarHBondContact O-CB 3.25Å; A268-V305 PolarHBondContact O-N 3.27Å; A268-A308 HydrophobicContact CB-CB 3.76Å
269F95.6Very high95.6Very high12 Ų1222.2 Ų22.25%0.05312%0.123CC..EExtended strand (participates in β ladder)trans-129.9108.7-176.6-61.7-89.3000109.6W102 Q245 K261 N262 T263W102-F269 HydrophobicContact CH2-CZ 4.24Å; W102-F269 HydrophobicContact CZ3-CZ 4.49Å; Q245-F269 HydrophobicContact CB-CB 4.27Å; Q245-F269 HydrophobicContact CG-CB 3.63Å; Q245-F269 HydrophobicContact CG-CD1 3.99Å; Q245-F269 HydrophobicContact CG-CD2 3.9Å; Q245-F269 HydrophobicContact CG-CG 3.58Å; K261-F269 PolarHBondContact NZ-O 2.86Å; N262-F269 WeakPolarHBondContact CA-O 3.43Å; N262-F269 PolarHBondContact OD1-N 3.06Å; N262-F269 PolarHBondContact OD1-O 3.26Å; T263-F269 PolarHBondContact N-O 2.79Å; T263-F269 PolarHBondContact O-N 3.42Å
270I98Very high95.6Very high0 Ų023.5 Ų23.50%013%0.131CC..EExtended strand (participates in β ladder)trans-88.9127.1177.6-53.168.8000106.7V260 K261 N262 E302 G303 V305 T387 V390 V391 M394V260-I270 HydrophobicContact CG1-CG2 3.58Å; K261-I270 CarbonylContact O-C 3.22Å; K261-I270 VanDerWaalsContact O-CA 3.27Å; K261-I270 WeakPolarHBondContact O-CA 3.18Å; N262-I270 HydrophobicContact CB-CG1 4.07Å; I270-E302 VanDerWaalsContact O-CA 3.3Å; I270-E302 WeakPolarHBondContact O-CA 3.29Å; I270-G303 PolarHBondContact N-O 3.46Å; I270-G303 VanDerWaalsContact N-O 3.07Å; I270-G303 PolarHBondContact O-N 3.19Å; I270-V305 HydrophobicContact CD1-CG2 4.2Å; I270-T387 HydrophobicContact CD1-CG2 4.3Å; I270-T387 HydrophobicContact CG1-CG2 4.05Å; I270-V390 HydrophobicContact CB-CG1 3.67Å; I270-V390 HydrophobicContact CD1-CB 3.96Å; I270-V390 HydrophobicContact CD1-CG1 3.84Å; I270-V390 HydrophobicContact CD1-CG2 4.24Å; I270-V390 HydrophobicContact CG1-CB 4.18Å; I270-V390 HydrophobicContact CG1-CG1 3.77Å; I270-V390 HydrophobicContact CG2-CG1 4.24Å; I270-V391 HydrophobicContact CG1-CG2 4.39Å; I270-V391 HydrophobicContact CG2-CG2 4.1Å; I270-M394 HydrophobicContact CB-CE 3.92Å; I270-M394 HydrophobicContact CB-SD 4.34Å; I270-M394 HydrophobicContact CG2-CE 3.69Å; I270-M394 HydrophobicContact CG2-SD 3.5Å; I270-M394 VanDerWaalsContact CG2-SD 3.5Å; I270-M394 WeakPolarHBondContact O-CE 3.33Å
271V98.2Very high95.5Very high0 Ų023.3 Ų23.30%013%0.13CC..EExtended strand (participates in β ladder)trans-133.3125.5-179.6-171.10000109.1Q245 L249 V260 K261 A300 L301 E302Q245-V271 HydrophobicContact CB-CG2 4.1Å; L249-V271 HydrophobicContact CD1-CB 4.31Å; L249-V271 HydrophobicContact CD1-CG1 4.15Å; L249-V271 HydrophobicContact CD2-CG1 3.95Å; L249-V271 HydrophobicContact CG-CG1 4.45Å; V260-V271 WeakPolarHBondContact CA-O 3.13Å; K261-V271 PolarHBondContact N-O 2.83Å; K261-V271 PolarHBondContact O-N 3.32Å; V271-A300 HydrophobicContact CG1-CB 3.74Å; V271-L301 WeakPolarHBondContact CA-O 3.48Å; V271-E302 HydrophobicContact CG2-CG 4.23Å
272M98Very high95.2Very high2 Ų231.9 Ų31.91%0.0117%0.17CC..EExtended strand (participates in β ladder)trans-110.5128.2175.5172.7-175.7-73.300109.7M259 V260 T274 A300 L301 M394 I402M259-M272 WeakPolarHBondContact O-CA 3.3Å; V260-M272 HydrophobicContact CG1-CB 4.44Å; V260-M272 HydrophobicContact CG2-CB 3.83Å; V260-M272 HydrophobicContact CG2-CE 3.44Å; V260-M272 VanDerWaalsContact CG2-CE 3.44Å; V260-M272 HydrophobicContact CG2-CG 3.86Å; M272-T274 PolarHBondContact O-N 3.37Å; M272-A300 CarbonylContact O-C 3.53Å; M272-A300 WeakPolarHBondContact O-CA 3.39Å; M272-A300 VanDerWaalsContact O-CB 3.25Å; M272-A300 WeakPolarHBondContact O-CB 3.16Å; M272-L301 HydrophobicContact CB-CB 4.39Å; M272-L301 PolarHBondContact N-O 3.24Å; M272-L301 PolarHBondContact O-N 2.92Å; M272-M394 HydrophobicContact CB-SD 4.02Å; M272-M394 HydrophobicContact CE-CB 4.23Å; M272-I402 HydrophobicContact CE-CD1 3.43Å; M272-I402 VanDerWaalsContact CE-CD1 3.43Å; M272-I402 HydrophobicContact CE-CG1 3.43Å; M272-I402 VanDerWaalsContact CE-CG1 3.43Å
273N98Very high95Very high1 Ų134.2 Ų34.21%0.00518%0.182CC..EExtended strand (participates in β ladder)trans-70.4125.6169.5-178.7-32.9000110.3L249 A254 F255 G258 M259 G275 Y291 T298L249-N273 HydrophobicContact CD2-CB 4.44Å; A254-N273 PolarHBondContact O-ND2 2.95Å; F255-N273 PolarHBondContact O-ND2 3.2Å; G258-N273 PolarHBondContact N-O 2.83Å; M259-N273 PolarHBondContact O-N 3.2Å; N273-G275 PolarHBondContact OD1-N 2.86Å; N273-Y291 PolarHBondContact ND2-OH 2.9Å; N273-T298 VanDerWaalsContact OD1-CG2 3.26Å; N273-T298 WeakPolarHBondContact OD1-CG2 3.26Å
274T97.6Very high94.9Very high1 Ų134.5 Ų34.51%0.00619%0.187CC..EExtended strand (participates in β ladder)trans-105.90.3179.1640000114K257 M272 E277 I279 Y299 L301K257-T274 WeakPolarHBondContact CD-O 3.11Å; K257-T274 WeakPolarHBondContact CE-O 3.41Å; M272-T274 PolarHBondContact O-N 3.37Å; T274-E277 PolarHBondContact OG1-O 3.47Å; T274-I279 HydrophobicContact CG2-CB 4.44Å; T274-I279 HydrophobicContact CG2-CD1 3.79Å; T274-I279 HydrophobicContact CG2-CG1 4.05Å; T274-Y299 PolarHBondContact N-O 3.22Å; T274-Y299 VanDerWaalsContact OG1-C 3.27Å; T274-Y299 VanDerWaalsContact OG1-CB 3.29Å; T274-Y299 WeakPolarHBondContact OG1-CB 3.04Å; T274-Y299 PolarHBondContact OG1-O 3.38Å; T274-L301 HydrophobicContact CG2-CB 4.26Å; T274-L301 HydrophobicContact CG2-CD1 4.28Å; T274-L301 HydrophobicContact CG2-CG 3.97Å
275G97.1Very high95Very high15 Ų1534.5 Ų34.516%0.15519%0.187CC..EExtended strand (participates in β ladder)trans78.5-156.9-175.100000112.7N273 E277 Y299N273-G275 PolarHBondContact OD1-N 2.86Å; G275-E277 PolarHBondContact O-N 2.84Å; G275-Y299 PolarHBondContact O-N 2.75Å
276E97.3Very high95.4Very high108 Ų10833.1 Ų33.151%0.50517%0.173SC..THydrogen-bonded Turntrans-73.7-7.7-178.9-58.9-176.3-139.100113.3K296 V297 Y299E276-K296 IonicContact OE1-NZ 2.79Å; E276-K296 PolarHBondContact OE1-NZ 2.77Å; E276-V297 WeakPolarHBondContact CA-O 3.43Å; E276-Y299 WeakPolarHBondContact O-CD2 3.44Å; E276-Y299 WeakPolarHBondContact O-CE2 3.32Å
277E96Very high96Very high138 Ų13831.6 Ų31.665%0.64516%0.163SC*.SBendtrans-106.5121.3178.5-65.3-66.7158.100110.5T274 G275T274-E277 PolarHBondContact OG1-O 3.47Å; G275-E277 PolarHBondContact O-N 2.84Å
278P96.3Very high96.4Very high34 Ų3431.5 Ų31.522%0.22116%0.163CC..  trans-71.2143.7175.228.2-31.4000110.9Y194 T287 Y299Y194-P278 HydrophobicContact CD1-CG 3.93Å; Y194-P278 HydrophobicContact CE1-CB 4.08Å; Y194-P278 HydrophobicContact CE1-CG 3.54Å; P278-T287 HydrophobicContact CB-CG2 3.83Å; P278-Y299 HydrophobicContact CB-CD1 3.75Å; P278-Y299 HydrophobicContact CB-CD2 4.08Å; P278-Y299 HydrophobicContact CB-CE1 4.08Å; P278-Y299 HydrophobicContact CB-CE2 4.39Å; P278-Y299 HydrophobicContact CB-CG 3.75Å; P278-Y299 HydrophobicContact CG-CD1 4.47Å; P278-Y299 HydrophobicContact CG-CD2 4.3Å; P278-Y299 HydrophobicContact CG-CE1 4.37Å; P278-Y299 HydrophobicContact CG-CE2 4.21Å; P278-Y299 HydrophobicContact CG-CG 4.43Å
279I96.3Very high96.6Very high34 Ų3431.5 Ų31.517%0.17416%0.162CC..  trans-107.7113.5170-57.9179.7000107.3T274 S281 T287 L301 D397T274-I279 HydrophobicContact CG2-CB 4.44Å; T274-I279 HydrophobicContact CG2-CD1 3.79Å; T274-I279 HydrophobicContact CG2-CG1 4.05Å; I279-S281 PolarHBondContact O-N 2.79Å; I279-T287 WeakPolarHBondContact O-CB 3.44Å; I279-T287 VanDerWaalsContact O-CG2 3.22Å; I279-T287 WeakPolarHBondContact O-CG2 3.37Å; I279-T287 PolarHBondContact O-OG1 3.38Å; I279-L301 HydrophobicContact CB-CD1 3.98Å; I279-L301 HydrophobicContact CB-CD2 4.46Å; I279-L301 HydrophobicContact CB-CG 4.19Å; I279-L301 HydrophobicContact CD1-CD1 4.32Å; I279-L301 HydrophobicContact CG2-CD1 3.93Å; I279-L301 WeakPolarHBondContact O-CD2 3.34Å; I279-D397 WeakPolarHBondContact CG2-O 3.36Å
280L95.6Very high96.7Very high70 Ų7030.9 Ų30.937%0.36616%0.16SC..  trans-73.7121.3173.5-173.965.1000109.4Q124 T287Q124-L280 HydrophobicContact CG-CD1 3.89Å; L280-T287 WeakPolarHBondContact CA-OG1 3.45Å
281S94.7Very high96.8Very high2 Ų231.3 Ų31.31%0.01416%0.162CC..  trans-72.2134177.7178.30000112.3Q124 I279 N283 G284 L285 T287 D397Q124-S281 PolarHBondContact NE2-O 2.87Å; I279-S281 PolarHBondContact O-N 2.79Å; S281-N283 PolarHBondContact OG-N 2.66Å; S281-G284 PolarHBondContact OG-N 3.4Å; S281-L285 VanDerWaalsContact CB-O 3.28Å; S281-L285 WeakPolarHBondContact CB-O 3.47Å; S281-L285 WeakPolarHBondContact OG-CA 3.05Å; S281-L285 WeakPolarHBondContact OG-CB 3.44Å; S281-L285 PolarHBondContact OG-N 3.02Å; S281-T287 PolarHBondContact N-OG1 2.69Å; S281-D397 VanDerWaalsContact CB-OD2 3.29Å; S281-D397 WeakPolarHBondContact CB-OD2 3.17Å; S281-D397 PolarHBondContact OG-OD2 2.81Å
282E92.1Very high96.8Very high179 Ų17931.4 Ų31.484%0.83616%0.162SC*.SBendtrans-102.8-3.9170.6-62.6-174165.200112.4D397E282-D397 PolarHBondContact N-OD1 3.24Å
283N93.8Very high96.7Very high50 Ų5031.8 Ų31.827%0.26716%0.164SC..SBendtrans-125.420.1-169.3-64.3-82.6000113.9S281 T393 K396 D397S281-N283 PolarHBondContact OG-N 2.66Å; N283-T393 HydrophobicContact CB-CG2 3.54Å; N283-T393 WeakPolarHBondContact O-CG2 3.19Å; N283-K396 WeakPolarHBondContact OD1-CE 3.26Å; N283-K396 PolarHBondContact OD1-NZ 3.23Å; N283-D397 WeakPolarHBondContact CB-OD1 3.38Å; N283-D397 PolarHBondContact ND2-OD1 3.16Å
284G93.2Very high96.5Very high15 Ų1538.8 Ų38.816%0.15520%0.202CC..SBendtrans89.726.8172.800000114.8S281 W355S281-G284 PolarHBondContact OG-N 3.4Å; G284-W355 PolarHBondContact O-NE1 3.42Å
285L96.9Very high96.4Very high0 Ų042.8 Ų42.80%024%0.243CC..PPolyproline II helixtrans-95.5170.6164.1-57.1179.4000110.6S281 L301 A352 V390 T393 M394 D397S281-L285 VanDerWaalsContact CB-O 3.28Å; S281-L285 WeakPolarHBondContact CB-O 3.47Å; S281-L285 WeakPolarHBondContact OG-CA 3.05Å; S281-L285 WeakPolarHBondContact OG-CB 3.44Å; S281-L285 PolarHBondContact OG-N 3.02Å; L285-L301 HydrophobicContact CB-CD2 4.29Å; L285-A352 HydrophobicContact CD2-CB 4.29Å; L285-V390 HydrophobicContact CD2-CG1 4.08Å; L285-T393 HydrophobicContact CD1-CG2 3.99Å; L285-T393 HydrophobicContact CD2-CG2 4.03Å; L285-T393 HydrophobicContact CG-CG2 3.71Å; L285-M394 HydrophobicContact CD1-CB 4.08Å; L285-M394 HydrophobicContact CD1-CG 3.35Å; L285-M394 HydrophobicContact CD2-CG 4.47Å; L285-D397 HydrophobicContact CD1-CB 4.35Å; L285-D397 WeakPolarHBondContact CD1-OD2 3.4Å
286L97.8Very high96.4Very high0 Ų047.4 Ų47.40%026%0.259CS..EExtended strand (participates in β ladder)trans-103.7132.7175-53.8177000109.6L129 L130 Y134 F135 L301 E302 W355L129-L286 HydrophobicContact CD2-CB 4.24Å; L129-L286 HydrophobicContact CD2-CD1 4.48Å; L129-L286 HydrophobicContact CD2-CD2 4.35Å; L130-L286 HydrophobicContact CG-CD2 4.27Å; Y134-L286 HydrophobicContact CE1-CD1 4.44Å; F135-L286 HydrophobicContact CE1-CD1 4.03Å; F135-L286 HydrophobicContact CZ-CD1 3.8Å; F135-L286 HydrophobicContact CZ-CD2 3.84Å; F135-L286 HydrophobicContact CZ-CG 4.49Å; L286-L301 CarbonylContact O-C 3.55Å; L286-L301 WeakPolarHBondContact O-CA 3.26Å; L286-E302 HydrophobicContact CB-CB 4.36Å; L286-E302 PolarHBondContact N-O 2.84Å; L286-E302 PolarHBondContact O-N 3.24Å; L286-W355 HydrophobicContact CD1-CH2 3.98Å; L286-W355 HydrophobicContact CD1-CZ2 4.04Å; L286-W355 HydrophobicContact CD2-CH2 3.97Å; L286-W355 HydrophobicContact CD2-CZ2 3.63Å; L286-W355 HydrophobicContact CG-CH2 4.23Å; L286-W355 HydrophobicContact CG-CZ2 3.82Å
287T98.4Very high96.4Very high0 Ų043.1 Ų43.10%024%0.24CC..EExtended strand (participates in β ladder)trans-91.2123.9164.9-470000107.5G128 I193 P278 I279 L280 S281G128-T287 CarbonylContact C-O 3.6Å; G128-T287 VanDerWaalsContact CA-O 3.3Å; G128-T287 WeakPolarHBondContact CA-O 3.29Å; G128-T287 PolarHBondContact O-N 2.65Å; I193-T287 HydrophobicContact CD1-CG2 3.97Å; P278-T287 HydrophobicContact CB-CG2 3.83Å; I279-T287 WeakPolarHBondContact O-CB 3.44Å; I279-T287 VanDerWaalsContact O-CG2 3.22Å; I279-T287 WeakPolarHBondContact O-CG2 3.37Å; I279-T287 PolarHBondContact O-OG1 3.38Å; L280-T287 WeakPolarHBondContact CA-OG1 3.45Å; S281-T287 PolarHBondContact N-OG1 2.69Å
288T98.6Very high96.6Very high0 Ų037.4 Ų37.40%022%0.215CC..EExtended strand (participates in β ladder)trans-139.3165.3-173.7-161.70000110.2S186 R187 Q246 Y299 A300 E302S186-T288 PolarHBondContact OG-OG1 3.37Å; R187-T288 VanDerWaalsContact CD-OG1 3.26Å; R187-T288 WeakPolarHBondContact CD-OG1 3.49Å; R187-T288 PolarHBondContact NH1-OG1 2.91Å; Q246-T288 PolarHBondContact NE2-OG1 3.07Å; T288-Y299 WeakPolarHBondContact O-CA 3.38Å; T288-A300 HydrophobicContact CG2-CB 3.94Å; T288-A300 PolarHBondContact N-O 2.88Å; T288-A300 PolarHBondContact O-N 3.42Å; T288-E302 HydrophobicContact CG2-CB 4.4Å
289I98.8Very high96.7Very high0 Ų036.7 Ų36.70%021%0.208CC..EExtended strand (participates in β ladder)trans-77.3130.1166.6-61.1174.4000108.3Y182 T183 S186 Y191 I193 L196 Q246 V297 Y299Y182-I289 HydrophobicContact CD1-CD1 4.49Å; Y182-I289 HydrophobicContact CG-CD1 4.48Å; T183-I289 HydrophobicContact CG2-CG2 4.35Å; S186-I289 PolarHBondContact OG-N 3.23Å; Y191-I289 HydrophobicContact CE1-CD1 4.14Å; I193-I289 HydrophobicContact CB-CD1 4.16Å; I193-I289 HydrophobicContact CB-CG1 4.07Å; I193-I289 HydrophobicContact CG2-CD1 4.2Å; I193-I289 HydrophobicContact CG2-CG1 4.13Å; L196-I289 HydrophobicContact CD2-CD1 3.72Å; Q246-I289 WeakPolarHBondContact CG-O 3.47Å; Q246-I289 PolarHBondContact NE2-O 3.05Å; I289-V297 HydrophobicContact CD1-CG1 4.31Å; I289-V297 HydrophobicContact CG1-CG1 4.2Å; I289-V297 HydrophobicContact CG2-CG1 3.73Å; I289-Y299 HydrophobicContact CG1-CD1 4.19Å; I289-Y299 HydrophobicContact CG1-CE1 4.02Å
290G98.5Very high96.8Very high0 Ų035 Ų350%020%0.199CC..EExtended strand (participates in β ladder)trans-81.2-48.8175.500000112.1T183 Q246 T298T183-G290 VanDerWaalsContact CG2-C 3.49Å; T183-G290 WeakPolarHBondContact CG2-O 3.39Å; Q246-G290 VanDerWaalsContact CB-O 3.26Å; Q246-G290 WeakPolarHBondContact CB-O 3.22Å; Q246-G290 WeakPolarHBondContact CG-O 3.37Å; G290-T298 VanDerWaalsContact CA-O 3.29Å; G290-T298 WeakPolarHBondContact CA-O 3.49Å; G290-T298 PolarHBondContact N-O 2.68Å
291Y98.7Very high96.9Very high9 Ų931.7 Ų31.74%0.03518%0.182CC..EExtended strand (participates in β ladder)trans-174.5157.2170.645.9-96.5000110.3L249 V250 F255 N273 I293 T298L249-Y291 HydrophobicContact CD2-CE1 4.26Å; V250-Y291 HydrophobicContact CG2-CD1 3.63Å; V250-Y291 HydrophobicContact CG2-CE1 4.17Å; V250-Y291 HydrophobicContact CG2-CG 4.17Å; F255-Y291 WeakPolarHBondContact CA-OH 3.48Å; F255-Y291 HydrophobicContact CD1-CE1 4.44Å; F255-Y291 HydrophobicContact CD1-CE2 4.33Å; F255-Y291 AromaticContact CD1-CZ 3.85Å; F255-Y291 PolarHBondContact O-OH 2.73Å; N273-Y291 PolarHBondContact ND2-OH 2.9Å; Y291-I293 HydrophobicContact CD2-CD1 3.66Å; Y291-I293 HydrophobicContact CD2-CG1 3.85Å; Y291-I293 HydrophobicContact CE2-CD1 4.1Å; Y291-I293 HydrophobicContact CG-CD1 4.28Å; Y291-T298 HydrophobicContact CE1-CG2 4.18Å; Y291-T298 HydrophobicContact CE2-CG2 4.14Å; Y291-T298 WeakPolarHBondContact CE2-OG1 3.27Å; Y291-T298 PolarHBondContact N-O 3.3Å; Y291-T298 VanDerWaalsContact N-O 3.14Å; Y291-T298 PolarHBondContact O-N 2.73Å
292G98.4Very high97Very high1 Ų131.6 Ų31.61%0.0118%0.181CC..EExtended strand (participates in β ladder)trans-110.9122.1164.400000112N219 K296N219-G292 WeakPolarHBondContact CB-O 3.26Å; N219-G292 PolarHBondContact N-O 3.49Å; N219-G292 PolarHBondContact OD1-N 3.16Å; G292-K296 CarbonylContact C-O 3.59Å; G292-K296 VanDerWaalsContact CA-O 3.23Å; G292-K296 WeakPolarHBondContact CA-O 3.45Å
293I97.3Very high97.3Very high10 Ų1023.1 Ų23.15%0.05114%0.141CC..EExtended strand (participates in β ladder)trans-139.6140.9178.4-57.4172.8000107.9F255 Y291 G295 K296 L445F255-I293 HydrophobicContact CE1-CD1 4.44Å; Y291-I293 HydrophobicContact CD2-CD1 3.66Å; Y291-I293 HydrophobicContact CD2-CG1 3.85Å; Y291-I293 HydrophobicContact CE2-CD1 4.1Å; Y291-I293 HydrophobicContact CG-CD1 4.28Å; I293-G295 PolarHBondContact O-N 3.38Å; I293-G295 VanDerWaalsContact O-N 3.17Å; I293-K296 PolarHBondContact N-O 3.07Å; I293-K296 PolarHBondContact O-N 3Å; I293-L445 HydrophobicContact CD1-CD2 3.57Å; I293-L445 HydrophobicContact CG1-CD2 3.96Å
294D93.4Very high97.2Very high148 Ų14820.7 Ų20.779%0.79113%0.129SC*.THydrogen-bonded Turntrans52.737.6177.1-63.1-30.5000114.5K296D294-K296 PolarHBondContact O-N 3.46Å
295G94.5Very high97.3Very high85 Ų8520 Ų2088%0.87612%0.122SC*.THydrogen-bonded Turntrans73.37.6179.500000114.9I293I293-G295 PolarHBondContact O-N 3.38Å; I293-G295 VanDerWaalsContact O-N 3.17Å
296K97.2Very high96.9Very high112 Ų11220.5 Ų20.549%0.48712%0.124SC..EExtended strand (participates in β ladder)trans-109.2143.2175.7-65.9-179.5164.3-141.60110.8E276 G292 I293 D294E276-K296 IonicContact OE1-NZ 2.79Å; E276-K296 PolarHBondContact OE1-NZ 2.77Å; G292-K296 CarbonylContact C-O 3.59Å; G292-K296 VanDerWaalsContact CA-O 3.23Å; G292-K296 WeakPolarHBondContact CA-O 3.45Å; I293-K296 PolarHBondContact N-O 3.07Å; I293-K296 PolarHBondContact O-N 3Å; D294-K296 PolarHBondContact O-N 3.46Å
297V98.5Very high96.5Very high19 Ų1920.8 Ų20.812%0.11513%0.125CC..EExtended strand (participates in β ladder)trans-106.5123.4174.4177.70000108.9Y182 L196 E276 I289 Y299Y182-V297 HydrophobicContact CD2-CG2 4.42Å; Y182-V297 HydrophobicContact CE2-CG2 4.28Å; L196-V297 HydrophobicContact CD1-CG2 3.7Å; L196-V297 HydrophobicContact CD2-CG1 4.42Å; L196-V297 HydrophobicContact CD2-CG2 4.21Å; E276-V297 WeakPolarHBondContact CA-O 3.43Å; I289-V297 HydrophobicContact CD1-CG1 4.31Å; I289-V297 HydrophobicContact CG1-CG1 4.2Å; I289-V297 HydrophobicContact CG2-CG1 3.73Å; V297-Y299 HydrophobicContact CG1-CE1 4.42Å; V297-Y299 HydrophobicContact CG1-CE2 4.13Å
298T98.7Very high96.3Very high17 Ų1720.8 Ų20.810%0.10413%0.125CC..EExtended strand (participates in β ladder)trans-101.2129.1170.9-63.60000108.7N273 G290 Y291N273-T298 VanDerWaalsContact OD1-CG2 3.26Å; N273-T298 WeakPolarHBondContact OD1-CG2 3.26Å; G290-T298 VanDerWaalsContact CA-O 3.29Å; G290-T298 WeakPolarHBondContact CA-O 3.49Å; G290-T298 PolarHBondContact N-O 2.68Å; Y291-T298 HydrophobicContact CE1-CG2 4.18Å; Y291-T298 HydrophobicContact CE2-CG2 4.14Å; Y291-T298 WeakPolarHBondContact CE2-OG1 3.27Å; Y291-T298 PolarHBondContact N-O 3.3Å; Y291-T298 VanDerWaalsContact N-O 3.14Å; Y291-T298 PolarHBondContact O-N 2.73Å
299Y98.6Very high95.9Very high19 Ų1921.4 Ų21.48%0.07513%0.131CC..EExtended strand (participates in β ladder)trans-90.9165.4175.9-66-86.6000112I193 T274 G275 E276 P278 T288 I289 V297I193-Y299 HydrophobicContact CB-CE1 4.19Å; I193-Y299 HydrophobicContact CD1-CD1 4.33Å; I193-Y299 HydrophobicContact CD1-CE1 4.16Å; I193-Y299 HydrophobicContact CG1-CE1 4.3Å; I193-Y299 WeakPolarHBondContact O-CE1 3.29Å; I193-Y299 PolarHBondContact O-OH 2.82Å; T274-Y299 PolarHBondContact N-O 3.22Å; T274-Y299 VanDerWaalsContact OG1-C 3.27Å; T274-Y299 VanDerWaalsContact OG1-CB 3.29Å; T274-Y299 WeakPolarHBondContact OG1-CB 3.04Å; T274-Y299 PolarHBondContact OG1-O 3.38Å; G275-Y299 PolarHBondContact O-N 2.75Å; E276-Y299 WeakPolarHBondContact O-CD2 3.44Å; E276-Y299 WeakPolarHBondContact O-CE2 3.32Å; P278-Y299 HydrophobicContact CB-CD1 3.75Å; P278-Y299 HydrophobicContact CB-CD2 4.08Å; P278-Y299 HydrophobicContact CB-CE1 4.08Å; P278-Y299 HydrophobicContact CB-CE2 4.39Å; P278-Y299 HydrophobicContact CB-CG 3.75Å; P278-Y299 HydrophobicContact CG-CD1 4.47Å; P278-Y299 HydrophobicContact CG-CD2 4.3Å; P278-Y299 HydrophobicContact CG-CE1 4.37Å; P278-Y299 HydrophobicContact CG-CE2 4.21Å; P278-Y299 HydrophobicContact CG-CG 4.43Å; T288-Y299 WeakPolarHBondContact O-CA 3.38Å; I289-Y299 HydrophobicContact CG1-CD1 4.19Å; I289-Y299 HydrophobicContact CG1-CE1 4.02Å; V297-Y299 HydrophobicContact CG1-CE1 4.42Å; V297-Y299 HydrophobicContact CG1-CE2 4.13Å
300A98.5Very high95.5Very high0 Ų022.5 Ų22.50%014%0.139CC..EExtended strand (participates in β ladder)trans-141.5152.7174.500000112.2V271 M272 T288V271-A300 HydrophobicContact CG1-CB 3.74Å; M272-A300 CarbonylContact O-C 3.53Å; M272-A300 WeakPolarHBondContact O-CA 3.39Å; M272-A300 VanDerWaalsContact O-CB 3.25Å; M272-A300 WeakPolarHBondContact O-CB 3.16Å; T288-A300 HydrophobicContact CG2-CB 3.94Å; T288-A300 PolarHBondContact N-O 2.88Å; T288-A300 PolarHBondContact O-N 3.42Å
301L97.7Very high95.3Very high0 Ų022.5 Ų22.50%014%0.139CC..EExtended strand (participates in β ladder)trans-96.5136.5160.3-83.2173.8000108.8V271 M272 T274 I279 L285 L286 M394 D397V271-L301 WeakPolarHBondContact CA-O 3.48Å; M272-L301 HydrophobicContact CB-CB 4.39Å; M272-L301 PolarHBondContact N-O 3.24Å; M272-L301 PolarHBondContact O-N 2.92Å; T274-L301 HydrophobicContact CG2-CB 4.26Å; T274-L301 HydrophobicContact CG2-CD1 4.28Å; T274-L301 HydrophobicContact CG2-CG 3.97Å; I279-L301 HydrophobicContact CB-CD1 3.98Å; I279-L301 HydrophobicContact CB-CD2 4.46Å; I279-L301 HydrophobicContact CB-CG 4.19Å; I279-L301 HydrophobicContact CD1-CD1 4.32Å; I279-L301 HydrophobicContact CG2-CD1 3.93Å; I279-L301 WeakPolarHBondContact O-CD2 3.34Å; L285-L301 HydrophobicContact CB-CD2 4.29Å; L286-L301 CarbonylContact O-C 3.55Å; L286-L301 WeakPolarHBondContact O-CA 3.26Å; L301-M394 HydrophobicContact CB-CE 4.5Å; L301-M394 VanDerWaalsContact O-CE 3.3Å; L301-M394 WeakPolarHBondContact O-CE 3.41Å; L301-D397 HydrophobicContact CD1-CB 4.2Å
302E98.3Very high95.2Very high0 Ų022.7 Ų22.70%014%0.14CC..EExtended strand (participates in β ladder)trans-130.6139.5-179.8179.4-174.3148.700111.6R82 R187 I270 V271 L286 T288 S304R82-E302 IonicContact CZ-OE1 2.99Å; R82-E302 IonicContact CZ-OE2 2.83Å; R82-E302 IonicContact NH1-OE1 3.16Å; R82-E302 PolarHBondContact NH1-OE1 3.33Å; R82-E302 IonicContact NH1-OE2 2.77Å; R82-E302 PolarHBondContact NH1-OE2 3.26Å; R82-E302 IonicContact NH2-OE1 2.67Å; R82-E302 PolarHBondContact NH2-OE1 3.45Å; R82-E302 IonicContact NH2-OE2 2.65Å; R187-E302 IonicContact CZ-OE1 2.64Å; R187-E302 IonicContact CZ-OE2 3.56Å; R187-E302 IonicContact NH1-OE1 2.72Å; R187-E302 IonicContact NH1-OE2 3.33Å; R187-E302 PolarHBondContact NH1-OE2 3.01Å; R187-E302 IonicContact NH2-OE1 2.56Å; R187-E302 PolarHBondContact NH2-OE1 2.88Å; R187-E302 IonicContact NH2-OE2 2.81Å; R187-E302 PolarHBondContact NH2-OE2 3.32Å; I270-E302 VanDerWaalsContact O-CA 3.3Å; I270-E302 WeakPolarHBondContact O-CA 3.29Å; V271-E302 HydrophobicContact CG2-CG 4.23Å; L286-E302 HydrophobicContact CB-CB 4.36Å; L286-E302 PolarHBondContact N-O 2.84Å; L286-E302 PolarHBondContact O-N 3.24Å; T288-E302 HydrophobicContact CG2-CB 4.4Å; E302-S304 PolarHBondContact OE1-OG 3.23Å
303G97.2Very high95Very high0 Ų026.1 Ų26.10%016%0.156CC..EExtended strand (participates in β ladder)trans-122.9128161.800000110.9I270I270-G303 PolarHBondContact N-O 3.46Å; I270-G303 VanDerWaalsContact N-O 3.07Å; I270-G303 PolarHBondContact O-N 3.19Å
304S92.7Very high94.8Very high0 Ų029.2 Ų29.20%017%0.167CC..EExtended strand (participates in β ladder)trans-103.5117.7-174.6-41.20000110.2E302 G351 A352E302-S304 PolarHBondContact OE1-OG 3.23Å; S304-G351 CarbonylContact O-C 3.46Å; S304-G351 WeakPolarHBondContact O-CA 3.33Å; S304-A352 PolarHBondContact O-N 2.85Å
305V94Very high95Very high1 Ų122.2 Ų22.21%0.00613%0.13CC..EExtended strand (participates in β ladder)trans-103.9105.2171.7178.40000107.9G267 A268 I270 V307 Q386 V390G267-V305 CarbonylContact C-O 3.58Å; G267-V305 WeakPolarHBondContact CA-O 3.41Å; A268-V305 HydrophobicContact CB-CB 4.05Å; A268-V305 HydrophobicContact CB-CG1 4.49Å; A268-V305 PolarHBondContact N-O 2.89Å; A268-V305 WeakPolarHBondContact O-CA 3.47Å; A268-V305 VanDerWaalsContact O-CB 3.32Å; A268-V305 WeakPolarHBondContact O-CB 3.25Å; A268-V305 PolarHBondContact O-N 3.27Å; I270-V305 HydrophobicContact CD1-CG2 4.2Å; V305-V307 VanDerWaalsContact C-N 3.28Å; V305-V307 PolarHBondContact O-N 2.82Å; V305-Q386 HydrophobicContact CG1-CB 3.76Å; V305-Q386 HydrophobicContact CG1-CG 4.22Å; V305-Q386 HydrophobicContact CG2-CB 3.99Å; V305-V390 HydrophobicContact CG2-CG2 4.01Å
306F89.3Confident95.1Very high10 Ų1022 Ų224%0.04410%0.102CC..SBendtrans-65.8-28.3-169.5-56-38.3000114.3W102 Y134 G351 W355W102-F306 AromaticContact CZ3-CD1 3.98Å; W102-F306 HydrophobicContact CZ3-CD1 3.98Å; Y134-F306 HydrophobicContact CD1-CE1 4.25Å; Y134-F306 HydrophobicContact CE1-CE1 4.33Å; Y134-F306 HydrophobicContact CG-CE1 4.44Å; F306-G351 VanDerWaalsContact CE2-CA 3.41Å; F306-W355 HydrophobicContact CZ-CH2 4.46Å; F306-W355 AromaticContact CZ-CZ3 3.99Å; F306-W355 HydrophobicContact CZ-CZ3 3.99Å
307V89.3Confident94.9Very high6 Ų620.9 Ų20.94%0.03610%0.102CC..  trans-124.6107.4-174.3-179.20000109.9V305 S310 A311 P345 F347 Q386V305-V307 VanDerWaalsContact C-N 3.28Å; V305-V307 PolarHBondContact O-N 2.82Å; V307-S310 WeakPolarHBondContact CG1-OG 3.43Å; V307-A311 HydrophobicContact CG1-CB 3.96Å; V307-P345 HydrophobicContact CB-CB 4.5Å; V307-P345 WeakPolarHBondContact CB-O 3.48Å; V307-P345 HydrophobicContact CG1-CB 3.8Å; V307-P345 HydrophobicContact CG1-CG 4.28Å; V307-P345 VanDerWaalsContact CG1-O 3.28Å; V307-P345 WeakPolarHBondContact CG1-O 3.44Å; V307-P345 WeakPolarHBondContact CG2-O 3.39Å; V307-F347 HydrophobicContact CG1-CD2 3.65Å; V307-F347 HydrophobicContact CG1-CE2 3.79Å; V307-F347 HydrophobicContact CG2-CB 4.28Å; V307-F347 HydrophobicContact CG2-CD2 4.19Å; V307-Q386 PolarHBondContact O-NE2 3.36Å
308A93.9Very high94.6Very high0 Ų022.3 Ų22.30%012%0.12CC..SBendtrans-128.6-88.8172.900000110.7T266 A268 S310 A311 L383T266-A308 PolarHBondContact O-N 3.35Å; A268-A308 HydrophobicContact CB-CB 3.76Å; A308-S310 PolarHBondContact O-N 2.67Å; A308-A311 VanDerWaalsContact O-CB 3.3Å; A308-A311 WeakPolarHBondContact O-CB 3.41Å; A308-A311 PolarHBondContact O-N 2.7Å; A308-L383 HydrophobicContact CB-CD2 4.02Å; A308-L383 HydrophobicContact CB-CG 3.95Å
309G90.7Very high94.5Very high12 Ų1224.8 Ų24.812%0.12413%0.133CC..Hα-helixtrans-60-28176.200000113.2G265 T266 A311 I312 Q313G265-G309 WeakPolarHBondContact O-CA 3.5Å; G265-G309 PolarHBondContact O-N 3.46Å; T266-G309 PolarHBondContact O-N 3.19Å; G309-A311 VanDerWaalsContact C-N 3.25Å; G309-A311 PolarHBondContact O-N 3.01Å; G309-I312 PolarHBondContact O-N 3.21Å; G309-I312 VanDerWaalsContact O-N 3.11Å; G309-Q313 PolarHBondContact O-N 2.8Å
310S89.8Confident94.5Very high23 Ų2333.9 Ų33.916%0.16117%0.167CC..Hα-helixtrans-65-24.1173.652.70000113.5T266 V307 A308 Q313 W314T266-S310 PolarHBondContact O-N 3.05Å; T266-S310 PolarHBondContact O-OG 3.36Å; V307-S310 WeakPolarHBondContact CG1-OG 3.43Å; A308-S310 PolarHBondContact O-N 2.67Å; S310-Q313 PolarHBondContact O-N 2.88Å; S310-W314 WeakPolarHBondContact O-CB 3.45Å; S310-W314 PolarHBondContact O-N 2.71Å
311A95.5Very high94.4Very high0 Ų036.1 Ų36.10%018%0.178CC..Hα-helixtrans-66-41.5169.800000111.6V307 A308 G309 W314 L315 P345 F347 T379 L383V307-A311 HydrophobicContact CG1-CB 3.96Å; A308-A311 VanDerWaalsContact O-CB 3.3Å; A308-A311 WeakPolarHBondContact O-CB 3.41Å; A308-A311 PolarHBondContact O-N 2.7Å; G309-A311 VanDerWaalsContact C-N 3.25Å; G309-A311 PolarHBondContact O-N 3.01Å; A311-W314 WeakPolarHBondContact O-CB 3.37Å; A311-W314 PolarHBondContact O-N 3.45Å; A311-L315 WeakPolarHBondContact O-CG 3.03Å; A311-L315 PolarHBondContact O-N 2.88Å; A311-P345 HydrophobicContact CB-CB 4.04Å; A311-F347 HydrophobicContact CB-CE2 4.48Å; A311-T379 HydrophobicContact CB-CG2 3.79Å; A311-L383 HydrophobicContact CB-CD1 4.32Å
312I96.4Very high94.4Very high13 Ų1336.7 Ų36.77%0.06718%0.18CC..Hα-helixtrans-69.7-37.1177-54.1-54000110.9G309 L315 R316 F322 A325 T379 L380G309-I312 PolarHBondContact O-N 3.21Å; G309-I312 VanDerWaalsContact O-N 3.11Å; I312-L315 HydrophobicContact CD1-CD1 4.33Å; I312-L315 PolarHBondContact O-N 3.34Å; I312-R316 PolarHBondContact O-N 2.93Å; I312-R316 VanDerWaalsContact O-N 3.13Å; I312-F322 HydrophobicContact CG2-CE2 4.09Å; I312-F322 HydrophobicContact CG2-CZ 3.77Å; I312-F322 WeakPolarHBondContact O-CZ 3.45Å; I312-A325 HydrophobicContact CG2-CB 3.96Å; I312-T379 HydrophobicContact CD1-CG2 4.09Å; I312-L380 HydrophobicContact CD1-CD2 3.55Å; I312-L380 HydrophobicContact CD1-CG 3.96Å; I312-L380 HydrophobicContact CG1-CD2 4.18Å
313Q92.7Very high94.3Very high74 Ų7444.5 Ų44.535%0.34622%0.217SC..Hα-helixtrans-63.6-41.1170.8-67.9174.5-16.100111.6G309 S310 L315 R316 D317G309-Q313 PolarHBondContact O-N 2.8Å; S310-Q313 PolarHBondContact O-N 2.88Å; Q313-L315 VanDerWaalsContact C-N 3.35Å; Q313-L315 PolarHBondContact O-N 3.46Å; Q313-R316 CarbonylContact O-C 3.58Å; Q313-R316 WeakPolarHBondContact O-CA 3.33Å; Q313-R316 WeakPolarHBondContact O-CB 3.46Å; Q313-R316 PolarHBondContact O-N 3.2Å; Q313-D317 PolarHBondContact O-N 3.16Å
314W94.9Very high94.2Very high75 Ų7551.3 Ų51.328%0.28425%0.246SC..Hα-helixtrans-61.3-41.3175.5166.675.1000112.4S310 A311 R316 G318 L319 F347 F375S310-W314 WeakPolarHBondContact O-CB 3.45Å; S310-W314 PolarHBondContact O-N 2.71Å; A311-W314 WeakPolarHBondContact O-CB 3.37Å; A311-W314 PolarHBondContact O-N 3.45Å; W314-R316 VanDerWaalsContact C-N 3.26Å; W314-R316 PolarHBondContact O-N 2.95Å; W314-G318 VanDerWaalsContact O-CA 3.3Å; W314-G318 WeakPolarHBondContact O-CA 3.37Å; W314-G318 PolarHBondContact O-N 3.2Å; W314-L319 HydrophobicContact CD2-CD1 4.49Å; W314-L319 HydrophobicContact CD2-CG 4.33Å; W314-L319 HydrophobicContact CE3-CD1 4.4Å; W314-L319 HydrophobicContact CH2-CD1 3.37Å; W314-L319 HydrophobicContact CH2-CG 4.09Å; W314-L319 HydrophobicContact CZ2-CD1 3.41Å; W314-L319 VanDerWaalsContact CZ2-CD1 3.41Å; W314-L319 HydrophobicContact CZ2-CD2 4Å; W314-L319 HydrophobicContact CZ2-CG 3.63Å; W314-L319 HydrophobicContact CZ3-CD1 3.88Å; W314-L319 PolarHBondContact O-N 3.04Å; W314-F347 HydrophobicContact CB-CE2 3.88Å; W314-F347 HydrophobicContact CB-CZ 4.22Å; W314-F347 HydrophobicContact CD2-CE1 4.33Å; W314-F347 HydrophobicContact CD2-CE2 4.16Å; W314-F347 AromaticContact CD2-CZ 3.57Å; W314-F347 HydrophobicContact CD2-CZ 3.57Å; W314-F347 HydrophobicContact CE3-CE1 4.49Å; W314-F347 HydrophobicContact CE3-CE2 4.36Å; W314-F347 AromaticContact CE3-CZ 3.62Å; W314-F347 HydrophobicContact CE3-CZ 3.62Å; W314-F347 AromaticContact CG-CE2 3.96Å; W314-F347 HydrophobicContact CG-CE2 3.96Å; W314-F347 AromaticContact CG-CZ 3.85Å; W314-F347 HydrophobicContact CG-CZ 3.85Å; W314-F347 HydrophobicContact CZ3-CZ 4.12Å; W314-F375 HydrophobicContact CH2-CE1 4.12Å; W314-F375 HydrophobicContact CH2-CZ 4.03Å; W314-F375 HydrophobicContact CZ3-CE1 4.05Å; W314-F375 HydrophobicContact CZ3-CZ 4.39Å
315L97.5Very high94.2Very high0 Ų052.9 Ų52.90%026%0.26CS..Hα-helixtrans-59.3-38.4172-67.6-176.6000112A311 I312 Q313 L319 R320 M321 F322 F375 I376 T379A311-L315 WeakPolarHBondContact O-CG 3.03Å; A311-L315 PolarHBondContact O-N 2.88Å; I312-L315 HydrophobicContact CD1-CD1 4.33Å; I312-L315 PolarHBondContact O-N 3.34Å; Q313-L315 VanDerWaalsContact C-N 3.35Å; Q313-L315 PolarHBondContact O-N 3.46Å; L315-L319 HydrophobicContact CD2-CD1 4.12Å; L315-R320 PolarHBondContact O-N 3.44Å; L315-M321 HydrophobicContact CB-CB 4.4Å; L315-M321 HydrophobicContact CD2-CG 4.33Å; L315-M321 WeakPolarHBondContact O-CB 3.41Å; L315-M321 PolarHBondContact O-N 3.37Å; L315-F322 HydrophobicContact CB-CE1 3.62Å; L315-F322 HydrophobicContact CB-CE2 4.44Å; L315-F322 HydrophobicContact CB-CZ 3.51Å; L315-F322 HydrophobicContact CD1-CE1 3.81Å; L315-F322 HydrophobicContact CD1-CZ 4.08Å; L315-F322 HydrophobicContact CG-CE1 4.39Å; L315-F322 HydrophobicContact CG-CZ 4.45Å; L315-F375 HydrophobicContact CD2-CD1 3.89Å; L315-F375 HydrophobicContact CD2-CE1 3.55Å; L315-I376 HydrophobicContact CD1-CG1 4.22Å; L315-I376 HydrophobicContact CD1-CG2 4.46Å; L315-T379 HydrophobicContact CD1-CG2 3.76Å; L315-T379 HydrophobicContact CG-CG2 4.16Å
316R96.2Very high94.2Very high80 Ų8057.5 Ų57.530%0.30229%0.29SS..Hα-helixtrans-71.6-52.1179-171.5-171.164.9-169.1-4.5112.8I312 Q313 W314 R320 F322 Q323I312-R316 PolarHBondContact O-N 2.93Å; I312-R316 VanDerWaalsContact O-N 3.13Å; Q313-R316 CarbonylContact O-C 3.58Å; Q313-R316 WeakPolarHBondContact O-CA 3.33Å; Q313-R316 WeakPolarHBondContact O-CB 3.46Å; Q313-R316 PolarHBondContact O-N 3.2Å; W314-R316 VanDerWaalsContact C-N 3.26Å; W314-R316 PolarHBondContact O-N 2.95Å; R316-R320 VanDerWaalsContact O-CA 3.25Å; R316-R320 WeakPolarHBondContact O-CA 3.45Å; R316-F322 HydrophobicContact CB-CD2 4.03Å; R316-F322 HydrophobicContact CB-CE2 3.71Å; R316-F322 HydrophobicContact CG-CD2 4.25Å; R316-F322 HydrophobicContact CG-CE2 4.34Å; R316-F322 WeakPolarHBondContact CG-O 3.43Å; R316-Q323 WeakPolarHBondContact CD-O 3.23Å
317D92.7Very high94.6Very high89 Ų8959.7 Ų59.748%0.47630%0.3SS..Hα-helixtrans-97.1-43.3-165.8-59-28.5000112Q313Q313-D317 PolarHBondContact O-N 3.16Å
318G92.5Very high95Very high49 Ų4959.7 Ų59.751%0.50530%0.3SS..THydrogen-bonded Turntrans-76.8-61.3-179.500000111.6W314W314-G318 VanDerWaalsContact O-CA 3.3Å; W314-G318 WeakPolarHBondContact O-CA 3.37Å; W314-G318 PolarHBondContact O-N 3.2Å
319L96.8Very high95.2Very high69 Ų6961 Ų6136%0.36131%0.307SS..SBendtrans-87.2-12.4-177.6-63.7-168.2000114.3W314 L315 M321 F375W314-L319 HydrophobicContact CD2-CD1 4.49Å; W314-L319 HydrophobicContact CD2-CG 4.33Å; W314-L319 HydrophobicContact CE3-CD1 4.4Å; W314-L319 HydrophobicContact CH2-CD1 3.37Å; W314-L319 HydrophobicContact CH2-CG 4.09Å; W314-L319 HydrophobicContact CZ2-CD1 3.41Å; W314-L319 VanDerWaalsContact CZ2-CD1 3.41Å; W314-L319 HydrophobicContact CZ2-CD2 4Å; W314-L319 HydrophobicContact CZ2-CG 3.63Å; W314-L319 HydrophobicContact CZ3-CD1 3.88Å; W314-L319 PolarHBondContact O-N 3.04Å; L315-L319 HydrophobicContact CD2-CD1 4.12Å; L319-M321 HydrophobicContact CB-CE 4.16Å; L319-M321 HydrophobicContact CB-CG 3.81Å; L319-M321 HydrophobicContact CD1-CE 3.96Å; L319-M321 PolarHBondContact O-N 3.02Å; L319-F375 HydrophobicContact CD1-CE1 3.78Å; L319-F375 HydrophobicContact CD1-CZ 3.88Å
320R97.3Very high95.5Very high211 Ų21165.1 Ų65.180%0.79633%0.325SS*.  trans54.335.8178.9-55.6178.6-177.4178.1-0.6113.2L315 R316 F322L315-R320 PolarHBondContact O-N 3.44Å; R316-R320 VanDerWaalsContact O-CA 3.25Å; R316-R320 WeakPolarHBondContact O-CA 3.45Å; R320-F322 VanDerWaalsContact C-N 3.32Å
321M97.4Very high95.9Very high47 Ų4766.2 Ų66.223%0.23233%0.326CS..SBendtrans-69.3-31.7177.9-66.6-66-175.300110.8L315 L319 K372 I376L315-M321 HydrophobicContact CB-CB 4.4Å; L315-M321 HydrophobicContact CD2-CG 4.33Å; L315-M321 WeakPolarHBondContact O-CB 3.41Å; L315-M321 PolarHBondContact O-N 3.37Å; L319-M321 HydrophobicContact CB-CE 4.16Å; L319-M321 HydrophobicContact CB-CG 3.81Å; L319-M321 HydrophobicContact CD1-CE 3.96Å; L319-M321 PolarHBondContact O-N 3.02Å; M321-K372 WeakPolarHBondContact O-CE 3.39Å; M321-K372 PolarHBondContact O-NZ 3.41Å; M321-K372 HydrophobicContact SD-CD 4.45Å; M321-K372 HydrophobicContact SD-CG 4.01Å; M321-I376 HydrophobicContact CB-CD1 4.37Å
322F96.9Very high96Very high11 Ų1166.2 Ų66.25%0.04833%0.326CS..  trans-150.9166174.745.2-102.9000110.3I312 L315 R316 R320 K324 Q327 Y331 I376I312-F322 HydrophobicContact CG2-CE2 4.09Å; I312-F322 HydrophobicContact CG2-CZ 3.77Å; I312-F322 WeakPolarHBondContact O-CZ 3.45Å; L315-F322 HydrophobicContact CB-CE1 3.62Å; L315-F322 HydrophobicContact CB-CE2 4.44Å; L315-F322 HydrophobicContact CB-CZ 3.51Å; L315-F322 HydrophobicContact CD1-CE1 3.81Å; L315-F322 HydrophobicContact CD1-CZ 4.08Å; L315-F322 HydrophobicContact CG-CE1 4.39Å; L315-F322 HydrophobicContact CG-CZ 4.45Å; R316-F322 HydrophobicContact CB-CD2 4.03Å; R316-F322 HydrophobicContact CB-CE2 3.71Å; R316-F322 HydrophobicContact CG-CD2 4.25Å; R316-F322 HydrophobicContact CG-CE2 4.34Å; R316-F322 WeakPolarHBondContact CG-O 3.43Å; R320-F322 VanDerWaalsContact C-N 3.32Å; F322-K324 VanDerWaalsContact CD2-O 3.22Å; F322-K324 WeakPolarHBondContact CD2-O 3.29Å; F322-Q327 HydrophobicContact CB-CB 4.02Å; F322-Q327 HydrophobicContact CG-CB 4.4Å; F322-Y331 HydrophobicContact CB-CD2 4.25Å; F322-Y331 HydrophobicContact CB-CE2 3.91Å; F322-Y331 HydrophobicContact CD1-CD2 4.41Å; F322-I376 HydrophobicContact CD1-CD1 3.87Å; F322-I376 HydrophobicContact CD1-CG1 4.36Å; F322-I376 HydrophobicContact CE1-CD1 4.2Å; F322-I376 HydrophobicContact CE1-CG1 4.19Å; F322-I376 HydrophobicContact CE1-CG2 4.28Å
323Q95.9Very high96.1Very high164 Ų16471 Ų7177%0.76635%0.347SS*.SBendtrans-88.4-32.3-175.3-66-178.1-1700112.4R316R316-Q323 WeakPolarHBondContact CD-O 3.23Å
324K95.1Very high96.3Very high143 Ų14374.9 Ų74.962%0.62236%0.358SS*.SBendtrans-131.3138.5-178.1-58-176.2179.7-178.10110.1F322 P326 Q327F322-K324 VanDerWaalsContact CD2-O 3.22Å; F322-K324 WeakPolarHBondContact CD2-O 3.29Å; K324-P326 VanDerWaalsContact C-CD 3.44Å; K324-P326 VanDerWaalsContact C-N 3.33Å; K324-Q327 HydrophobicContact CB-CG 4.24Å; K324-Q327 VanDerWaalsContact O-CB 3.27Å; K324-Q327 WeakPolarHBondContact O-CB 3.32Å; K324-Q327 WeakPolarHBondContact O-CG 3.31Å; K324-Q327 PolarHBondContact O-N 3.15Å
325A93Very high96.5Very high34 Ų3472.2 Ų72.228%0.28135%0.35SS..THydrogen-bonded Turntrans-52.2-40.3-178.500000114.7I312 Q327 S328I312-A325 HydrophobicContact CG2-CB 3.96Å; A325-Q327 PolarHBondContact O-N 3.32Å; A325-Q327 VanDerWaalsContact O-N 3.14Å; A325-S328 VanDerWaalsContact O-CB 3.29Å; A325-S328 WeakPolarHBondContact O-CB 3.47Å; A325-S328 PolarHBondContact O-N 3.01Å; A325-S328 PolarHBondContact O-OG 2.87Å
326P95.3Very high96.3Very high97 Ų9779.8 Ų79.863%0.6339%0.391SS*.THydrogen-bonded Turntrans-60-24.7177.1-26.936.7000114.6K324 S328 E329K324-P326 VanDerWaalsContact C-CD 3.44Å; K324-P326 VanDerWaalsContact C-N 3.33Å; P326-S328 PolarHBondContact O-N 3.44Å; P326-S328 VanDerWaalsContact O-N 3.16Å; P326-E329 PolarHBondContact O-N 3.07Å
327Q97.3Very high96.4Very high57 Ų5778.4 Ų78.427%0.26639%0.393SS..Hα-helixtrans-65.9-17.8177.3-59.7180-65.400112.4F322 K324 A325 E329 D330 Y331F322-Q327 HydrophobicContact CB-CB 4.02Å; F322-Q327 HydrophobicContact CG-CB 4.4Å; K324-Q327 HydrophobicContact CB-CG 4.24Å; K324-Q327 VanDerWaalsContact O-CB 3.27Å; K324-Q327 WeakPolarHBondContact O-CB 3.32Å; K324-Q327 WeakPolarHBondContact O-CG 3.31Å; K324-Q327 PolarHBondContact O-N 3.15Å; A325-Q327 PolarHBondContact O-N 3.32Å; A325-Q327 VanDerWaalsContact O-N 3.14Å; Q327-E329 PolarHBondContact O-N 3.35Å; Q327-D330 PolarHBondContact O-N 3.2Å; Q327-Y331 HydrophobicContact CB-CD2 4.32Å; Q327-Y331 HydrophobicContact CB-CE2 4.32Å; Q327-Y331 WeakPolarHBondContact O-CD2 3.41Å; Q327-Y331 PolarHBondContact O-N 2.96Å
328S97.2Very high96.5Very high5 Ų574.2 Ų74.24%0.03537%0.371CS..Hα-helixtrans-56.4-37.917460.10000112A325 P326 A332 I376A325-S328 VanDerWaalsContact O-CB 3.29Å; A325-S328 WeakPolarHBondContact O-CB 3.47Å; A325-S328 PolarHBondContact O-N 3.01Å; A325-S328 PolarHBondContact O-OG 2.87Å; P326-S328 PolarHBondContact O-N 3.44Å; P326-S328 VanDerWaalsContact O-N 3.16Å; S328-A332 VanDerWaalsContact O-CB 3.3Å; S328-A332 WeakPolarHBondContact O-CB 3.4Å; S328-A332 PolarHBondContact O-N 2.96Å; S328-I376 VanDerWaalsContact O-CG2 3.31Å; S328-I376 WeakPolarHBondContact O-CG2 3.4Å
329E97.8Very high96.7Very high29 Ų2976.6 Ų76.614%0.13637%0.369CS..Hα-helixtrans-66.6-47.2176.6-171.4172.2179.600111.7P326 Q327 Y331 A332 K333 D415 L416P326-E329 PolarHBondContact O-N 3.07Å; Q327-E329 PolarHBondContact O-N 3.35Å; E329-Y331 VanDerWaalsContact C-N 3.26Å; E329-Y331 PolarHBondContact O-N 3.07Å; E329-A332 PolarHBondContact O-N 2.77Å; E329-K333 HydrophobicContact CG-CD 4.13Å; E329-K333 WeakPolarHBondContact O-CB 3.35Å; E329-K333 WeakPolarHBondContact O-CG 3.25Å; E329-K333 PolarHBondContact O-N 3.5Å; E329-K333 WeakPolarHBondContact OE1-CE 3.43Å; E329-K333 IonicContact OE1-NZ 2.7Å; E329-K333 PolarHBondContact OE1-NZ 3.15Å; E329-D415 PolarHBondContact OE1-N 2.92Å; E329-L416 HydrophobicContact CG-CB 4.3Å
330D97.6Very high96.6Very high97 Ų9777.8 Ų77.852%0.51938%0.375SS..Hα-helixtrans-60.5-34.9178.7-66.4-30.4000112.6Q327 R334Q327-D330 PolarHBondContact O-N 3.2Å; D330-R334 WeakPolarHBondContact O-CG 3.39Å; D330-R334 PolarHBondContact O-NE 2.79Å
331Y98.1Very high96.7Very high46 Ų4667.7 Ų67.718%0.1834%0.338CS..Hα-helixtrans-75.8-43.8175.7-80.7-68.5000111.7F322 Q327 E329 K333 R334 K372 E373 I376F322-Y331 HydrophobicContact CB-CD2 4.25Å; F322-Y331 HydrophobicContact CB-CE2 3.91Å; F322-Y331 HydrophobicContact CD1-CD2 4.41Å; Q327-Y331 HydrophobicContact CB-CD2 4.32Å; Q327-Y331 HydrophobicContact CB-CE2 4.32Å; Q327-Y331 WeakPolarHBondContact O-CD2 3.41Å; Q327-Y331 PolarHBondContact O-N 2.96Å; E329-Y331 VanDerWaalsContact C-N 3.26Å; E329-Y331 PolarHBondContact O-N 3.07Å; Y331-K333 VanDerWaalsContact C-N 3.28Å; Y331-K333 PolarHBondContact O-N 3.34Å; Y331-R334 WeakPolarHBondContact O-CB 3.3Å; Y331-R334 PolarHBondContact O-N 3.43Å; Y331-K372 HydrophobicContact CE1-CD 4.44Å; Y331-K372 PolarHBondContact OH-NZ 2.7Å; Y331-E373 HydrophobicContact CD1-CG 4.22Å; Y331-E373 WeakPolarHBondContact CD1-OE1 3.47Å; Y331-E373 WeakPolarHBondContact O-CG 3.21Å; Y331-I376 HydrophobicContact CD1-CD1 4.37Å; Y331-I376 HydrophobicContact CD2-CD1 3.93Å; Y331-I376 HydrophobicContact CG-CD1 3.7Å
332A98.1Very high96.8Very high0 Ų066.1 Ų66.10%033%0.329CS..Hα-helixtrans-64.8-31.5-179.900000112.9S328 E329 R334 V335 I376 R377 L380 L416S328-A332 VanDerWaalsContact O-CB 3.3Å; S328-A332 WeakPolarHBondContact O-CB 3.4Å; S328-A332 PolarHBondContact O-N 2.96Å; E329-A332 PolarHBondContact O-N 2.77Å; A332-R334 PolarHBondContact O-N 3.41Å; A332-V335 WeakPolarHBondContact O-CG2 3.37Å; A332-I376 HydrophobicContact CB-CG2 4.44Å; A332-R377 HydrophobicContact CB-CB 3.91Å; A332-R377 HydrophobicContact CB-CG 4.37Å; A332-R377 WeakPolarHBondContact O-CD 3.48Å; A332-L380 HydrophobicContact CB-CD1 3.66Å; A332-L416 HydrophobicContact CB-CD1 3.97Å; A332-L416 HydrophobicContact CB-CD2 4.37Å
333K97.7Very high96.9Very high114 Ų11465.8 Ų65.850%0.49633%0.328SS..THydrogen-bonded Turntrans-72.2-8.2176-75.2179.7-179.3173.10114.9E329 Y331 V335 L416E329-K333 HydrophobicContact CG-CD 4.13Å; E329-K333 WeakPolarHBondContact O-CB 3.35Å; E329-K333 WeakPolarHBondContact O-CG 3.25Å; E329-K333 PolarHBondContact O-N 3.5Å; E329-K333 WeakPolarHBondContact OE1-CE 3.43Å; E329-K333 IonicContact OE1-NZ 2.7Å; E329-K333 PolarHBondContact OE1-NZ 3.15Å; Y331-K333 VanDerWaalsContact C-N 3.28Å; Y331-K333 PolarHBondContact O-N 3.34Å; K333-V335 VanDerWaalsContact C-N 3.29Å; K333-L416 HydrophobicContact CB-CD1 4.47Å; K333-L416 HydrophobicContact CG-CD1 3.56Å
334R97.9Very high97Very high155 Ų15558 Ų5859%0.58529%0.291SS*.THydrogen-bonded Turntrans-82.9-7.8179.7-68.2169.5-167.8-155.9-4.5113.7D330 Y331 A332 E373D330-R334 WeakPolarHBondContact O-CG 3.39Å; D330-R334 PolarHBondContact O-NE 2.79Å; Y331-R334 WeakPolarHBondContact O-CB 3.3Å; Y331-R334 PolarHBondContact O-N 3.43Å; A332-R334 PolarHBondContact O-N 3.41Å; R334-E373 HydrophobicContact CB-CB 4.5Å; R334-E373 HydrophobicContact CB-CG 3.82Å
335V97.8Very high97.1Very high19 Ų1951.2 Ų51.212%0.11526%0.262CS..SBendtrans-129.8144179.1-67.10000108.3A332 K333 S337 E373 H374 R377A332-V335 WeakPolarHBondContact O-CG2 3.37Å; K333-V335 VanDerWaalsContact C-N 3.29Å; V335-S337 VanDerWaalsContact C-N 3.33Å; V335-S337 WeakPolarHBondContact CG2-O 3.41Å; V335-E373 HydrophobicContact CB-CB 4.42Å; V335-E373 HydrophobicContact CG1-CB 3.52Å; V335-E373 HydrophobicContact CG1-CG 4.42Å; V335-E373 HydrophobicContact CG2-CB 4.01Å; V335-H374 VanDerWaalsContact CG1-CD2 3.49Å; V335-H374 WeakPolarHBondContact CG1-CD2 3.43Å; V335-H374 VanDerWaalsContact CG1-NE2 3.31Å; V335-H374 WeakPolarHBondContact CG1-NE2 3.47Å; V335-R377 HydrophobicContact CG2-CB 4.23Å; V335-R377 PolarHBondContact O-NH1 3.48Å
336D94.7Very high97.2Very high159 Ų15949.6 Ų49.685%0.8525%0.249SC*.SBendtrans-74.9-26.7-175.4-63-35000112.1R377D336-R377 PolarHBondContact O-NH1 3.04Å; D336-R377 PolarHBondContact O-NH2 3.06Å
337S96.4Very high97Very high51 Ų5148.1 Ų48.136%0.35723%0.233SC..SBendtrans-149.4178.4178.572.50000111.4V335 E339 H374V335-S337 VanDerWaalsContact C-N 3.33Å; V335-S337 WeakPolarHBondContact CG2-O 3.41Å; S337-E339 VanDerWaalsContact C-N 3.28Å; S337-E339 PolarHBondContact OG-N 2.92Å; S337-E339 VanDerWaalsContact OG-N 3.1Å; S337-H374 PolarHBondContact O-CD2 3.1Å; S337-H374 VanDerWaalsContact O-CD2 3.31Å
338S96.5Very high96.4Very high1 Ų147.3 Ų47.31%0.00723%0.232CC..  trans-81.2-0.416849.70000114N340 V341 E381S338-N340 VanDerWaalsContact C-N 3.34Å; S338-N340 PolarHBondContact O-N 3.23Å; S338-V341 VanDerWaalsContact O-CB 3.22Å; S338-V341 WeakPolarHBondContact O-CB 3.41Å; S338-V341 VanDerWaalsContact O-CG2 3.24Å; S338-V341 WeakPolarHBondContact O-CG2 3.27Å; S338-V341 PolarHBondContact O-N 3.08Å; S338-E381 WeakPolarHBondContact CB-OE2 3.4Å; S338-E381 PolarHBondContact OG-OE2 2.72Å
339E95.7Very high96.1Very high100 Ų10047.2 Ų47.247%0.46723%0.232SC..THydrogen-bonded Turntrans50.845.8-177.4-64-170156.400113.8S337 V341 H374S337-E339 VanDerWaalsContact C-N 3.28Å; S337-E339 PolarHBondContact OG-N 2.92Å; S337-E339 VanDerWaalsContact OG-N 3.1Å; E339-V341 PolarHBondContact O-N 3.19Å; E339-H374 IonicContact OE1-CE1 3.44Å; E339-H374 IonicContact OE1-NE2 3.05Å; E339-H374 IonicContact OE2-CE1 2.74Å; E339-H374 PolarHBondContact OE2-CE1 3.31Å; E339-H374 IonicContact OE2-ND1 3.4Å; E339-H374 PolarHBondContact OE2-ND1 3.23Å; E339-H374 IonicContact OE2-NE2 3.52Å
340N95.9Very high96Very high93 Ų9346 Ų4650%0.49723%0.226SC..THydrogen-bonded Turntrans62.416.7-175.6-77.7-33.4000115.2S338 Y342 G365S338-N340 VanDerWaalsContact C-N 3.34Å; S338-N340 PolarHBondContact O-N 3.23Å; N340-Y342 HydrophobicContact CB-CE2 4.42Å; N340-Y342 VanDerWaalsContact O-CD2 3.26Å; N340-Y342 WeakPolarHBondContact O-CD2 3.07Å; N340-G365 WeakPolarHBondContact O-CA 3.3Å
341V98.6Very high95.8Very high0 Ų041.6 Ų41.60%020%0.203CC..  trans-78123.6167.4-179.60000108.9S338 E339 I363 F364 L366 T370 A378S338-V341 VanDerWaalsContact O-CB 3.22Å; S338-V341 WeakPolarHBondContact O-CB 3.41Å; S338-V341 VanDerWaalsContact O-CG2 3.24Å; S338-V341 WeakPolarHBondContact O-CG2 3.27Å; S338-V341 PolarHBondContact O-N 3.08Å; E339-V341 PolarHBondContact O-N 3.19Å; V341-I363 HydrophobicContact CG1-CG2 4.31Å; V341-F364 WeakPolarHBondContact CA-O 3.14Å; V341-L366 HydrophobicContact CG1-CD2 3.92Å; V341-L366 HydrophobicContact CG2-CD2 4.29Å; V341-T370 HydrophobicContact CG2-CG2 3.76Å; V341-A378 HydrophobicContact CB-CB 4.11Å; V341-A378 HydrophobicContact CG1-CB 3.83Å; V341-A378 WeakPolarHBondContact O-CB 3.22Å
342Y98.8Very high95.7Very high14 Ų1439.6 Ų39.66%0.05520%0.196CC..EExtended strand (participates in β ladder)trans-115.7128.7175-66.9-85.4000109.8N340 I363 F364 Y385 L481 W485 A488N340-Y342 HydrophobicContact CB-CE2 4.42Å; N340-Y342 VanDerWaalsContact O-CD2 3.26Å; N340-Y342 WeakPolarHBondContact O-CD2 3.07Å; Y342-I363 CarbonylContact O-C 3.59Å; Y342-I363 VanDerWaalsContact O-CA 3.32Å; Y342-I363 WeakPolarHBondContact O-CA 3.18Å; Y342-F364 PolarHBondContact N-O 3.33Å; Y342-F364 VanDerWaalsContact N-O 3.1Å; Y342-F364 PolarHBondContact O-N 3.26Å; Y342-Y385 HydrophobicContact CD1-CE2 4.07Å; Y342-Y385 AromaticContact CE1-CE2 3.87Å; Y342-Y385 HydrophobicContact CE1-CE2 3.87Å; Y342-Y385 AromaticContact CE1-CZ 3.95Å; Y342-L481 PolarHBondContact OH-O 3.04Å; Y342-L481 VanDerWaalsContact OH-O 3.06Å; Y342-W485 HydrophobicContact CD1-CB 4.1Å; Y342-W485 HydrophobicContact CD1-CE3 4.41Å; Y342-W485 HydrophobicContact CE1-CB 3.92Å; Y342-W485 VanDerWaalsContact CE1-N 3.3Å; Y342-A488 HydrophobicContact CG-CB 4.11Å
343V98.7Very high95.6Very high3 Ų340.9 Ų40.92%0.01821%0.205CC..EExtended strand (participates in β ladder)trans-107.6122.2170.9175.70000107.3P345 I363 A378 S382V343-P345 WeakPolarHBondContact O-CD 3.22Å; V343-I363 HydrophobicContact CG2-CG1 4.37Å; V343-I363 HydrophobicContact CG2-CG2 4.2Å; V343-A378 HydrophobicContact CG2-CB 3.87Å; V343-S382 WeakPolarHBondContact O-CB 3.28Å
344V98.6Very high95.5Very high0 Ų037.6 Ų37.60%019%0.19CC..EExtended strand (participates in β ladder)trans-106.598.2174.4-176.50000107.4A346 L350 G361 A362 F364 W485 A488 V489 T492V344-A346 HydrophobicContact CG1-CB 4.41Å; V344-A346 PolarHBondContact O-N 3.11Å; V344-L350 HydrophobicContact CG1-CD2 4.09Å; V344-G361 VanDerWaalsContact O-CA 3.27Å; V344-G361 WeakPolarHBondContact O-CA 3.36Å; V344-A362 PolarHBondContact N-O 3.36Å; V344-A362 PolarHBondContact O-N 3.09Å; V344-F364 HydrophobicContact CG2-CE2 4.39Å; V344-W485 HydrophobicContact CB-CZ3 4.46Å; V344-W485 HydrophobicContact CG1-CH2 4.3Å; V344-W485 HydrophobicContact CG2-CE3 4.47Å; V344-W485 HydrophobicContact CG2-CH2 4.31Å; V344-W485 HydrophobicContact CG2-CZ3 3.86Å; V344-A488 HydrophobicContact CG2-CB 3.99Å; V344-V489 HydrophobicContact CG1-CG2 4.32Å; V344-V489 HydrophobicContact CG2-CG2 4.28Å; V344-T492 HydrophobicContact CB-CG2 4.43Å; V344-T492 HydrophobicContact CG1-CG2 3.98Å
345P97.2Very high95.3Very high1 Ų132.1 Ų32.11%0.00617%0.169CC..  trans-83.649.1-168.336.8-39.4000113V307 A311 V343 F347V307-P345 HydrophobicContact CB-CB 4.5Å; V307-P345 WeakPolarHBondContact CB-O 3.48Å; V307-P345 HydrophobicContact CG1-CB 3.8Å; V307-P345 HydrophobicContact CG1-CG 4.28Å; V307-P345 VanDerWaalsContact CG1-O 3.28Å; V307-P345 WeakPolarHBondContact CG1-O 3.44Å; V307-P345 WeakPolarHBondContact CG2-O 3.39Å; A311-P345 HydrophobicContact CB-CB 4.04Å; V343-P345 WeakPolarHBondContact O-CD 3.22Å; P345-F347 HydrophobicContact CB-CE1 4.4Å; P345-F347 HydrophobicContact CB-CE2 4.33Å; P345-F347 HydrophobicContact CB-CZ 4.06Å; P345-F347 PolarHBondContact O-N 3.33Å
346A95.3Very high95Very high1 Ų132.4 Ų32.41%0.00817%0.17CC..  trans-7645.5-177.400000114V344 T348 G349 L350 A359 R360 G361V344-A346 HydrophobicContact CG1-CB 4.41Å; V344-A346 PolarHBondContact O-N 3.11Å; A346-T348 PolarHBondContact O-N 2.97Å; A346-T348 VanDerWaalsContact O-N 3.14Å; A346-G349 PolarHBondContact O-N 2.81Å; A346-G349 VanDerWaalsContact O-N 3.11Å; A346-L350 HydrophobicContact CB-CD2 3.69Å; A346-L350 HydrophobicContact CB-CG 3.71Å; A346-A359 HydrophobicContact CB-CB 4.21Å; A346-R360 CarbonylContact O-C 3.59Å; A346-R360 WeakPolarHBondContact O-CA 3.48Å; A346-G361 PolarHBondContact O-N 2.9Å
347F90.1Very high94.7Very high65 Ų6525.8 Ų25.829%0.28513%0.134SC..THydrogen-bonded Turntrans-57.9-32.6-171.1-54.9-35.1000113.9V307 A311 W314 P345V307-F347 HydrophobicContact CG1-CD2 3.65Å; V307-F347 HydrophobicContact CG1-CE2 3.79Å; V307-F347 HydrophobicContact CG2-CB 4.28Å; V307-F347 HydrophobicContact CG2-CD2 4.19Å; A311-F347 HydrophobicContact CB-CE2 4.48Å; W314-F347 HydrophobicContact CB-CE2 3.88Å; W314-F347 HydrophobicContact CB-CZ 4.22Å; W314-F347 HydrophobicContact CD2-CE1 4.33Å; W314-F347 HydrophobicContact CD2-CE2 4.16Å; W314-F347 AromaticContact CD2-CZ 3.57Å; W314-F347 HydrophobicContact CD2-CZ 3.57Å; W314-F347 HydrophobicContact CE3-CE1 4.49Å; W314-F347 HydrophobicContact CE3-CE2 4.36Å; W314-F347 AromaticContact CE3-CZ 3.62Å; W314-F347 HydrophobicContact CE3-CZ 3.62Å; W314-F347 AromaticContact CG-CE2 3.96Å; W314-F347 HydrophobicContact CG-CE2 3.96Å; W314-F347 AromaticContact CG-CZ 3.85Å; W314-F347 HydrophobicContact CG-CZ 3.85Å; W314-F347 HydrophobicContact CZ3-CZ 4.12Å; P345-F347 HydrophobicContact CB-CE1 4.4Å; P345-F347 HydrophobicContact CB-CE2 4.33Å; P345-F347 HydrophobicContact CB-CZ 4.06Å; P345-F347 PolarHBondContact O-N 3.33Å
348T85.8Confident94.3Very high41 Ų4127.5 Ų27.525%0.25214%0.136SC..THydrogen-bonded Turntrans-117.428.3179.751.90000112.1K105 A346K105-T348 VanDerWaalsContact CE-O 3.23Å; K105-T348 WeakPolarHBondContact CE-O 3.46Å; A346-T348 PolarHBondContact O-N 2.97Å; A346-T348 VanDerWaalsContact O-N 3.14Å
349G91.1Very high94.2Very high3 Ų327.4 Ų27.43%0.03114%0.136CC..  trans91.8172.9-169.500000112.6A346 D356 A359A346-G349 PolarHBondContact O-N 2.81Å; A346-G349 VanDerWaalsContact O-N 3.11Å; G349-D356 CarbonylContact C-O 3.42Å; G349-D356 VanDerWaalsContact CA-O 3.26Å; G349-D356 WeakPolarHBondContact CA-O 3.36Å; G349-A359 WeakPolarHBondContact CA-O 3.39Å; G349-A359 PolarHBondContact N-O 3.11Å
350L94.8Very high94Very high3 Ų327.7 Ų27.72%0.01613%0.133CC..BIsolated β-bridgetrans-94.2132.8170.1-71.5166.2000109.5V344 A346 Y354 W355 D356 A359 V489 M493V344-L350 HydrophobicContact CG1-CD2 4.09Å; A346-L350 HydrophobicContact CB-CD2 3.69Å; A346-L350 HydrophobicContact CB-CG 3.71Å; L350-Y354 HydrophobicContact CB-CD2 4.18Å; L350-Y354 HydrophobicContact CB-CG 4.35Å; L350-Y354 HydrophobicContact CD1-CD2 4.28Å; L350-Y354 HydrophobicContact CD1-CG 4.23Å; L350-Y354 HydrophobicContact CD2-CD2 4.37Å; L350-W355 WeakPolarHBondContact O-CA 3.23Å; L350-D356 HydrophobicContact CB-CB 4.29Å; L350-D356 PolarHBondContact N-O 2.65Å; L350-D356 PolarHBondContact O-N 3.37Å; L350-A359 HydrophobicContact CB-CB 4.44Å; L350-A359 HydrophobicContact CD1-CB 3.88Å; L350-A359 HydrophobicContact CG-CB 3.89Å; L350-V489 HydrophobicContact CD1-CG1 3.84Å; L350-M493 HydrophobicContact CD1-CG 3.75Å; L350-M493 HydrophobicContact CD1-SD 4.19Å
351G93.6Very high94Very high4 Ų425.2 Ų25.24%0.04113%0.128CC..  trans-82.9-147.3171.700000111.9S304 F306 Y354 W355S304-G351 CarbonylContact O-C 3.46Å; S304-G351 WeakPolarHBondContact O-CA 3.33Å; F306-G351 VanDerWaalsContact CE2-CA 3.41Å; G351-Y354 PolarHBondContact O-N 3.06Å; G351-W355 PolarHBondContact O-N 3.32Å
352A95.8Very high94Very high4 Ų426.3 Ų26.33%0.03314%0.138CC..THydrogen-bonded Turntrans-61.5146.5178.900000111.9L285 S304 Y354 W355 V390L285-A352 HydrophobicContact CD2-CB 4.29Å; S304-A352 PolarHBondContact O-N 2.85Å; A352-Y354 VanDerWaalsContact C-N 3.32Å; A352-W355 HydrophobicContact CB-CZ2 4.27Å; A352-V390 HydrophobicContact CB-CG2 4.18Å
353P96.4Very high94Very high28 Ų2828.4 Ų28.418%0.18215%0.149CC..THydrogen-bonded Turncis-84.13.3-5.835-36.4000114D389 T393P353-D389 HydrophobicContact CG-CB 4.18Å; P353-T393 HydrophobicContact CB-CG2 4.22Å
354Y95.6Very high94Very high45 Ų4531.5 Ų31.518%0.17616%0.163CC..THydrogen-bonded Turntrans-82.4-40.5-167.3-53.1-73.4000114.8L350 G351 A352 D356 D389 Q486 V489 M493L350-Y354 HydrophobicContact CB-CD2 4.18Å; L350-Y354 HydrophobicContact CB-CG 4.35Å; L350-Y354 HydrophobicContact CD1-CD2 4.28Å; L350-Y354 HydrophobicContact CD1-CG 4.23Å; L350-Y354 HydrophobicContact CD2-CD2 4.37Å; G351-Y354 PolarHBondContact O-N 3.06Å; A352-Y354 VanDerWaalsContact C-N 3.32Å; Y354-D356 VanDerWaalsContact C-N 3.33Å; Y354-D356 PolarHBondContact O-N 2.87Å; Y354-D389 HydrophobicContact CE2-CB 4.42Å; Y354-D389 WeakPolarHBondContact CE2-OD2 3.47Å; Y354-D389 PolarHBondContact OH-OD2 2.92Å; Y354-Q486 PolarHBondContact OH-NE2 3.32Å; Y354-V489 HydrophobicContact CD1-CG1 3.95Å; Y354-V489 HydrophobicContact CD2-CG1 4.34Å; Y354-V489 HydrophobicContact CE1-CB 4.49Å; Y354-V489 HydrophobicContact CE1-CG1 3.53Å; Y354-V489 HydrophobicContact CE2-CG1 3.95Å; Y354-V489 HydrophobicContact CG-CG1 4.33Å; Y354-M493 HydrophobicContact CD1-CE 4.08Å; Y354-M493 HydrophobicContact CD1-SD 4.01Å; Y354-M493 HydrophobicContact CG-SD 4.39Å
355W93.5Very high93.9Very high39 Ų3933.3 Ų33.315%0.14818%0.182CC..  trans51.845.7-178.4-65.697.3000114.8L130 D132 Y134 F135 G284 L286 F306 L350 G351 A352L130-W355 HydrophobicContact CD1-CB 4.41Å; L130-W355 HydrophobicContact CD1-CD2 3.76Å; L130-W355 HydrophobicContact CD1-CG 3.6Å; L130-W355 HydrophobicContact CD1-CZ2 4.45Å; D132-W355 HydrophobicContact CB-CE3 4.33Å; D132-W355 HydrophobicContact CB-CZ3 4.21Å; Y134-W355 HydrophobicContact CD1-CH2 4.06Å; Y134-W355 HydrophobicContact CD1-CZ3 4.2Å; F135-W355 HydrophobicContact CZ-CH2 4.31Å; G284-W355 PolarHBondContact O-NE1 3.42Å; L286-W355 HydrophobicContact CD1-CH2 3.98Å; L286-W355 HydrophobicContact CD1-CZ2 4.04Å; L286-W355 HydrophobicContact CD2-CH2 3.97Å; L286-W355 HydrophobicContact CD2-CZ2 3.63Å; L286-W355 HydrophobicContact CG-CH2 4.23Å; L286-W355 HydrophobicContact CG-CZ2 3.82Å; F306-W355 HydrophobicContact CZ-CH2 4.46Å; F306-W355 AromaticContact CZ-CZ3 3.99Å; F306-W355 HydrophobicContact CZ-CZ3 3.99Å; L350-W355 WeakPolarHBondContact O-CA 3.23Å; G351-W355 PolarHBondContact O-N 3.32Å; A352-W355 HydrophobicContact CB-CZ2 4.27Å
356D92.4Very high94Very high26 Ų2638 Ų3814%0.13921%0.206CC..BIsolated β-bridgetrans-105.194.5-178.4-171.8-20.6000111.2G349 L350 Y354 Q358 A359 M493 K496G349-D356 CarbonylContact C-O 3.42Å; G349-D356 VanDerWaalsContact CA-O 3.26Å; G349-D356 WeakPolarHBondContact CA-O 3.36Å; L350-D356 HydrophobicContact CB-CB 4.29Å; L350-D356 PolarHBondContact N-O 2.65Å; L350-D356 PolarHBondContact O-N 3.37Å; Y354-D356 VanDerWaalsContact C-N 3.33Å; Y354-D356 PolarHBondContact O-N 2.87Å; D356-Q358 PolarHBondContact O-N 2.63Å; D356-Q358 PolarHBondContact OD1-N 3.38Å; D356-A359 HydrophobicContact CB-CB 4.07Å; D356-A359 PolarHBondContact O-N 3.47Å; D356-A359 PolarHBondContact OD1-N 3.09Å; D356-M493 HydrophobicContact CB-CG 4.48Å; D356-M493 HydrophobicContact CB-SD 4.4Å; D356-M493 VanDerWaalsContact OD2-CG 3.3Å; D356-M493 WeakPolarHBondContact OD2-CG 3.31Å; D356-K496 IonicContact OD1-NZ 3.49Å; D356-K496 PolarHBondContact OD1-NZ 3.41Å; D356-K496 IonicContact OD2-NZ 3.35Å; D356-K496 PolarHBondContact OD2-NZ 3.15Å
357Q87.3Confident94.1Very high20 Ų2042.2 Ų42.29%0.09323%0.232CC..THydrogen-bonded Turntrans-66.3-19.4180-59.9-176.741.800113.5S108 D132 S133 R360S108-Q357 PolarHBondContact OG-OE1 3.4Å; D132-Q357 WeakPolarHBondContact OD2-CG 3.39Å; D132-Q357 PolarHBondContact OD2-NE2 2.88Å; S133-Q357 PolarHBondContact OG-OE1 2.81Å; Q357-R360 PolarHBondContact O-NH1 3.24Å
358Q89.3Confident94.5Very high86 Ų8651 Ų5140%0.40226%0.263SS..THydrogen-bonded Turntrans-94.8-16.4-177.2-61.3-171.618.500113D356 R360 K496D356-Q358 PolarHBondContact O-N 2.63Å; D356-Q358 PolarHBondContact OD1-N 3.38Å; Q358-R360 PolarHBondContact O-NH1 2.99Å; Q358-K496 HydrophobicContact CB-CD 3.6Å
359A92.8Very high95Very high0 Ų051.1 Ų51.10%027%0.273CS..  trans-57.3146.5173.100000111.3A346 G349 L350 D356 T492A346-A359 HydrophobicContact CB-CB 4.21Å; G349-A359 WeakPolarHBondContact CA-O 3.39Å; G349-A359 PolarHBondContact N-O 3.11Å; L350-A359 HydrophobicContact CB-CB 4.44Å; L350-A359 HydrophobicContact CD1-CB 3.88Å; L350-A359 HydrophobicContact CG-CB 3.89Å; D356-A359 HydrophobicContact CB-CB 4.07Å; D356-A359 PolarHBondContact O-N 3.47Å; D356-A359 PolarHBondContact OD1-N 3.09Å; A359-T492 HydrophobicContact CB-CG2 4.41Å
360R92.5Very high95.4Very high106 Ų10652.6 Ų52.640%0.428%0.281SS..  trans-133.9161.8178.6-67-63.5-179.7-90.10.9110.1A346 Q357 Q358 A362 T492A346-R360 CarbonylContact O-C 3.59Å; A346-R360 WeakPolarHBondContact O-CA 3.48Å; Q357-R360 PolarHBondContact O-NH1 3.24Å; Q358-R360 PolarHBondContact O-NH1 2.99Å; R360-A362 PolarHBondContact O-N 3.25Å; R360-T492 WeakPolarHBondContact O-CG2 3.42Å
361G95.8Very high95.5Very high40 Ų4055.1 Ų55.141%0.41230%0.297SS..  trans-55.3130-179.300000112.8V344 A346V344-G361 VanDerWaalsContact O-CA 3.27Å; V344-G361 WeakPolarHBondContact O-CA 3.36Å; A346-G361 PolarHBondContact O-N 2.9Å
362A98.2Very high95.7Very high24 Ų2458.2 Ų58.220%0.19831%0.309CS..EExtended strand (participates in β ladder)trans-139.3158.3-175.500000112V344 R360 F364 T492V344-A362 PolarHBondContact N-O 3.36Å; V344-A362 PolarHBondContact O-N 3.09Å; R360-A362 PolarHBondContact O-N 3.25Å; A362-F364 HydrophobicContact CB-CE2 3.56Å; A362-F364 HydrophobicContact CB-CZ 3.83Å; A362-T492 HydrophobicContact CB-CG2 3.96Å
363I98.4Very high95.9Very high57 Ų5760 Ų6029%0.29232%0.316SS..EExtended strand (participates in β ladder)trans-140.4131.9-177-48.8-177.5000109.2V341 Y342 V343 L366 F375V341-I363 HydrophobicContact CG1-CG2 4.31Å; Y342-I363 CarbonylContact O-C 3.59Å; Y342-I363 VanDerWaalsContact O-CA 3.32Å; Y342-I363 WeakPolarHBondContact O-CA 3.18Å; V343-I363 HydrophobicContact CG2-CG1 4.37Å; V343-I363 HydrophobicContact CG2-CG2 4.2Å; I363-L366 HydrophobicContact CG2-CD1 4.19Å; I363-L366 HydrophobicContact CG2-CD2 3.97Å; I363-L366 HydrophobicContact CG2-CG 4.08Å; I363-F375 HydrophobicContact CD1-CE1 4.44Å; I363-F375 HydrophobicContact CD1-CE2 3.31Å; I363-F375 HydrophobicContact CD1-CZ 3.27Å; I363-F375 HydrophobicContact CG2-CE2 4.34Å
364F98.7Very high96Very high68 Ų6859.2 Ų59.230%0.29831%0.311SS..EExtended strand (participates in β ladder)trans-130165-176.5-56.6-85.7000111.4V341 Y342 V344 A362 L366 A488 A491 T492V341-F364 WeakPolarHBondContact CA-O 3.14Å; Y342-F364 PolarHBondContact N-O 3.33Å; Y342-F364 VanDerWaalsContact N-O 3.1Å; Y342-F364 PolarHBondContact O-N 3.26Å; V344-F364 HydrophobicContact CG2-CE2 4.39Å; A362-F364 HydrophobicContact CB-CE2 3.56Å; A362-F364 HydrophobicContact CB-CZ 3.83Å; F364-L366 VanDerWaalsContact C-N 3.31Å; F364-L366 PolarHBondContact O-N 2.95Å; F364-A488 HydrophobicContact CD2-CB 3.79Å; F364-A488 HydrophobicContact CE2-CB 4.34Å; F364-A488 WeakPolarHBondContact CE2-O 3.48Å; F364-A488 HydrophobicContact CG-CB 4.42Å; F364-A491 HydrophobicContact CD1-CB 4.48Å; F364-A491 HydrophobicContact CE1-CB 3.71Å; F364-A491 HydrophobicContact CE2-CB 4.45Å; F364-A491 HydrophobicContact CZ-CB 3.69Å; F364-T492 WeakPolarHBondContact CE2-OG1 3.42Å
365G98Very high96.1Very high39 Ų3958.3 Ų58.340%0.40231%0.307SS..  trans76.310.5174.800000115.9N340 T367N340-G365 WeakPolarHBondContact O-CA 3.3Å; G365-T367 PolarHBondContact O-N 3.36Å
366L98.3Very high96.3Very high99 Ų9956.4 Ų56.452%0.51830%0.3SS..  trans-64.6129.9179.1-61.1178.9000111.6V341 I363 F364 T370V341-L366 HydrophobicContact CG1-CD2 3.92Å; V341-L366 HydrophobicContact CG2-CD2 4.29Å; I363-L366 HydrophobicContact CG2-CD1 4.19Å; I363-L366 HydrophobicContact CG2-CD2 3.97Å; I363-L366 HydrophobicContact CG2-CG 4.08Å; F364-L366 VanDerWaalsContact C-N 3.31Å; F364-L366 PolarHBondContact O-N 2.95Å; L366-T370 HydrophobicContact CD2-CG2 3.81Å
367T98.1Very high96.6Very high89 Ų8956.8 Ų56.855%0.54630%0.3SS..  trans-119.8175.3170.677.30000110.3G365 G369 T370G365-T367 PolarHBondContact O-N 3.36Å; T367-G369 PolarHBondContact O-N 3.39Å; T367-G369 PolarHBondContact OG1-N 3.14Å; T367-G369 VanDerWaalsContact OG1-N 3.15Å; T367-T370 PolarHBondContact N-OG1 3.4Å; T367-T370 PolarHBondContact O-N 3.14Å; T367-T370 PolarHBondContact O-OG1 3.16Å
368R97.3Very high97.1Very high250 Ų25055.9 Ų55.994%0.94330%0.296SS*.THydrogen-bonded Turntrans-65.6-19.7174.1-172.354.1177.7156.71.3112.9
369G97.5Very high97.6Very high44 Ų4451.8 Ų51.845%0.45428%0.277SS..THydrogen-bonded Turntrans-85.4-12.8177.700000114.3T367 T371T367-G369 PolarHBondContact O-N 3.39Å; T367-G369 PolarHBondContact OG1-N 3.14Å; T367-G369 VanDerWaalsContact OG1-N 3.15Å; G369-T371 PolarHBondContact O-N 2.94Å
370T98.3Very high97.8Very high34 Ų3452 Ų5221%0.20928%0.278CS..  trans-59.9123.5-178.5-570000111.3V341 L366 T367 H374V341-T370 HydrophobicContact CG2-CG2 3.76Å; L366-T370 HydrophobicContact CD2-CG2 3.81Å; T367-T370 PolarHBondContact N-OG1 3.4Å; T367-T370 PolarHBondContact O-N 3.14Å; T367-T370 PolarHBondContact O-OG1 3.16Å; T370-H374 HydrophobicContact CG2-CB 4.04Å
371T98.1Very high98.1Very high56 Ų5647.1 Ų47.134%0.34426%0.26SS..  trans-100.2173.2178.366.60000110.9G369 E373 H374 F375G369-T371 PolarHBondContact O-N 2.94Å; T371-E373 WeakPolarHBondContact CB-OE2 3.13Å; T371-E373 PolarHBondContact O-N 2.8Å; T371-E373 PolarHBondContact OG1-N 2.67Å; T371-E373 PolarHBondContact OG1-OE2 3.1Å; T371-H374 PolarHBondContact N-ND1 3.4Å; T371-H374 PolarHBondContact O-N 3.09Å; T371-H374 PolarHBondContact OG1-N 3.35Å; T371-H374 PolarHBondContact OG1-ND1 3.16Å; T371-F375 PolarHBondContact O-N 2.92Å
372K97.9Very high98.2Very high69 Ų6945.3 Ų45.330%0.324%0.24SC..Hα-helixtrans-59.7-38.3170.7176.9-174.1175.8-173.20111.4M321 Y331 F375 I376M321-K372 WeakPolarHBondContact O-CE 3.39Å; M321-K372 PolarHBondContact O-NZ 3.41Å; M321-K372 HydrophobicContact SD-CD 4.45Å; M321-K372 HydrophobicContact SD-CG 4.01Å; Y331-K372 HydrophobicContact CE1-CD 4.44Å; Y331-K372 PolarHBondContact OH-NZ 2.7Å; K372-F375 WeakPolarHBondContact O-CB 3.24Å; K372-F375 PolarHBondContact O-N 2.9Å; K372-I376 HydrophobicContact CD-CD1 4.46Å; K372-I376 HydrophobicContact CG-CD1 3.81Å; K372-I376 VanDerWaalsContact O-CG1 3.29Å; K372-I376 WeakPolarHBondContact O-CG1 3.5Å; K372-I376 PolarHBondContact O-N 3.05Å
373E98.5Very high98.2Very high40 Ų4044.2 Ų44.219%0.18723%0.231CC..Hα-helixtrans-62.7-46.2178.7-68.367.6-158.800111.2Y331 R334 V335 T371 F375 I376 R377Y331-E373 HydrophobicContact CD1-CG 4.22Å; Y331-E373 WeakPolarHBondContact CD1-OE1 3.47Å; Y331-E373 WeakPolarHBondContact O-CG 3.21Å; R334-E373 HydrophobicContact CB-CB 4.5Å; R334-E373 HydrophobicContact CB-CG 3.82Å; V335-E373 HydrophobicContact CB-CB 4.42Å; V335-E373 HydrophobicContact CG1-CB 3.52Å; V335-E373 HydrophobicContact CG1-CG 4.42Å; V335-E373 HydrophobicContact CG2-CB 4.01Å; T371-E373 WeakPolarHBondContact CB-OE2 3.13Å; T371-E373 PolarHBondContact O-N 2.8Å; T371-E373 PolarHBondContact OG1-N 2.67Å; T371-E373 PolarHBondContact OG1-OE2 3.1Å; E373-F375 VanDerWaalsContact C-N 3.31Å; E373-F375 PolarHBondContact O-N 3.35Å; E373-I376 PolarHBondContact O-N 3.16Å; E373-R377 WeakPolarHBondContact O-CB 3.48Å; E373-R377 PolarHBondContact O-N 3.27Å
374H98.6Very high98.2Very high13 Ų1341.5 Ų41.56%0.0622%0.217CC..Hα-helixtrans-58.2-43.3174.1-63143.2000111.7V335 S337 E339 T370 T371 R377 A378V335-H374 VanDerWaalsContact CG1-CD2 3.49Å; V335-H374 WeakPolarHBondContact CG1-CD2 3.43Å; V335-H374 VanDerWaalsContact CG1-NE2 3.31Å; V335-H374 WeakPolarHBondContact CG1-NE2 3.47Å; S337-H374 PolarHBondContact O-CD2 3.1Å; S337-H374 VanDerWaalsContact O-CD2 3.31Å; E339-H374 IonicContact OE1-CE1 3.44Å; E339-H374 IonicContact OE1-NE2 3.05Å; E339-H374 IonicContact OE2-CE1 2.74Å; E339-H374 PolarHBondContact OE2-CE1 3.31Å; E339-H374 IonicContact OE2-ND1 3.4Å; E339-H374 PolarHBondContact OE2-ND1 3.23Å; E339-H374 IonicContact OE2-NE2 3.52Å; T370-H374 HydrophobicContact CG2-CB 4.04Å; T371-H374 PolarHBondContact N-ND1 3.4Å; T371-H374 PolarHBondContact O-N 3.09Å; T371-H374 PolarHBondContact OG1-N 3.35Å; T371-H374 PolarHBondContact OG1-ND1 3.16Å; H374-R377 PolarHBondContact O-N 2.61Å; H374-A378 WeakPolarHBondContact O-CB 3.11Å; H374-A378 PolarHBondContact O-N 3.04Å
375F98Very high98.2Very high25 Ų2538.3 Ų38.311%0.1120%0.203CC..Hα-helixtrans-64.3-44.3179.8-166.1-79.8000113W314 L315 L319 I363 T371 K372 E373 T379W314-F375 HydrophobicContact CH2-CE1 4.12Å; W314-F375 HydrophobicContact CH2-CZ 4.03Å; W314-F375 HydrophobicContact CZ3-CE1 4.05Å; W314-F375 HydrophobicContact CZ3-CZ 4.39Å; L315-F375 HydrophobicContact CD2-CD1 3.89Å; L315-F375 HydrophobicContact CD2-CE1 3.55Å; L319-F375 HydrophobicContact CD1-CE1 3.78Å; L319-F375 HydrophobicContact CD1-CZ 3.88Å; I363-F375 HydrophobicContact CD1-CE1 4.44Å; I363-F375 HydrophobicContact CD1-CE2 3.31Å; I363-F375 HydrophobicContact CD1-CZ 3.27Å; I363-F375 HydrophobicContact CG2-CE2 4.34Å; T371-F375 PolarHBondContact O-N 2.92Å; K372-F375 WeakPolarHBondContact O-CB 3.24Å; K372-F375 PolarHBondContact O-N 2.9Å; E373-F375 VanDerWaalsContact C-N 3.31Å; E373-F375 PolarHBondContact O-N 3.35Å; F375-T379 PolarHBondContact O-N 3.39Å; F375-T379 VanDerWaalsContact O-N 3.07Å; F375-T379 PolarHBondContact O-OG1 3.42Å
376I98.4Very high98.2Very high0 Ų037 Ų370%019%0.187CC..Hα-helixtrans-65.5-43177.4-67.8166.3000110L315 M321 F322 S328 Y331 A332 K372 E373 T379 L380L315-I376 HydrophobicContact CD1-CG1 4.22Å; L315-I376 HydrophobicContact CD1-CG2 4.46Å; M321-I376 HydrophobicContact CB-CD1 4.37Å; F322-I376 HydrophobicContact CD1-CD1 3.87Å; F322-I376 HydrophobicContact CD1-CG1 4.36Å; F322-I376 HydrophobicContact CE1-CD1 4.2Å; F322-I376 HydrophobicContact CE1-CG1 4.19Å; F322-I376 HydrophobicContact CE1-CG2 4.28Å; S328-I376 VanDerWaalsContact O-CG2 3.31Å; S328-I376 WeakPolarHBondContact O-CG2 3.4Å; Y331-I376 HydrophobicContact CD1-CD1 4.37Å; Y331-I376 HydrophobicContact CD2-CD1 3.93Å; Y331-I376 HydrophobicContact CG-CD1 3.7Å; A332-I376 HydrophobicContact CB-CG2 4.44Å; K372-I376 HydrophobicContact CD-CD1 4.46Å; K372-I376 HydrophobicContact CG-CD1 3.81Å; K372-I376 VanDerWaalsContact O-CG1 3.29Å; K372-I376 WeakPolarHBondContact O-CG1 3.5Å; K372-I376 PolarHBondContact O-N 3.05Å; E373-I376 PolarHBondContact O-N 3.16Å; I376-T379 WeakPolarHBondContact O-CB 3.16Å; I376-T379 PolarHBondContact O-N 3.16Å; I376-L380 PolarHBondContact O-N 3.25Å
377R98.4Very high98.2Very high33 Ų3332.3 Ų32.313%0.12516%0.162CC..Hα-helixtrans-61.7-49176.7-179.2142.4-177171.2-2111.9A332 V335 D336 E373 H374 T379 L380 E381A332-R377 HydrophobicContact CB-CB 3.91Å; A332-R377 HydrophobicContact CB-CG 4.37Å; A332-R377 WeakPolarHBondContact O-CD 3.48Å; V335-R377 HydrophobicContact CG2-CB 4.23Å; V335-R377 PolarHBondContact O-NH1 3.48Å; D336-R377 PolarHBondContact O-NH1 3.04Å; D336-R377 PolarHBondContact O-NH2 3.06Å; E373-R377 WeakPolarHBondContact O-CB 3.48Å; E373-R377 PolarHBondContact O-N 3.27Å; H374-R377 PolarHBondContact O-N 2.61Å; R377-T379 PolarHBondContact O-N 2.58Å; R377-L380 PolarHBondContact O-N 3.25Å; R377-E381 HydrophobicContact CG-CG 4.17Å; R377-E381 WeakPolarHBondContact CG-OE1 3.39Å; R377-E381 IonicContact CZ-OE1 3.67Å; R377-E381 IonicContact NE-OE1 3.7Å; R377-E381 PolarHBondContact NE-OE1 3.24Å; R377-E381 IonicContact NH2-OE1 2.77Å; R377-E381 WeakPolarHBondContact O-CG 3.23Å; R377-E381 PolarHBondContact O-N 2.97Å
378A98.7Very high98.2Very high2 Ų228 Ų282%0.01714%0.136CC..Hα-helixtrans-56.4-36.3175.200000112.8V341 V343 H374 S382V341-A378 HydrophobicContact CB-CB 4.11Å; V341-A378 HydrophobicContact CG1-CB 3.83Å; V341-A378 WeakPolarHBondContact O-CB 3.22Å; V343-A378 HydrophobicContact CG2-CB 3.87Å; H374-A378 WeakPolarHBondContact O-CB 3.11Å; H374-A378 PolarHBondContact O-N 3.04Å; A378-S382 WeakPolarHBondContact O-CB 3.21Å; A378-S382 PolarHBondContact O-N 2.93Å
379T98.5Very high98.2Very high0 Ų016.2 Ų16.20%09%0.092CC..Hα-helixtrans-67.4-42.6175.5-52.60000111.4A311 I312 L315 F375 I376 R377 S382 L383A311-T379 HydrophobicContact CB-CG2 3.79Å; I312-T379 HydrophobicContact CD1-CG2 4.09Å; L315-T379 HydrophobicContact CD1-CG2 3.76Å; L315-T379 HydrophobicContact CG-CG2 4.16Å; F375-T379 PolarHBondContact O-N 3.39Å; F375-T379 VanDerWaalsContact O-N 3.07Å; F375-T379 PolarHBondContact O-OG1 3.42Å; I376-T379 WeakPolarHBondContact O-CB 3.16Å; I376-T379 PolarHBondContact O-N 3.16Å; R377-T379 PolarHBondContact O-N 2.58Å; T379-S382 WeakPolarHBondContact O-CB 3.23Å; T379-S382 PolarHBondContact O-N 2.91Å; T379-S382 PolarHBondContact O-OG 3.48Å; T379-L383 WeakPolarHBondContact O-CD1 3.42Å
380L98Very high98.2Very high4 Ų414.1 Ų14.12%0.0217%0.07CC..Hα-helixtrans-65.1-45.7174.9-75.6167.7000111.8I312 A332 I376 R377 S382 L383 N414 L416 L417I312-L380 HydrophobicContact CD1-CD2 3.55Å; I312-L380 HydrophobicContact CD1-CG 3.96Å; I312-L380 HydrophobicContact CG1-CD2 4.18Å; A332-L380 HydrophobicContact CB-CD1 3.66Å; I376-L380 PolarHBondContact O-N 3.25Å; R377-L380 PolarHBondContact O-N 3.25Å; L380-S382 PolarHBondContact O-N 2.8Å; L380-L383 WeakPolarHBondContact O-CB 3.37Å; L380-L383 PolarHBondContact O-N 2.91Å; L380-L383 VanDerWaalsContact O-N 3.09Å; L380-N414 WeakPolarHBondContact CD1-ND2 3.42Å; L380-N414 WeakPolarHBondContact CD2-ND2 3.4Å; L380-L416 HydrophobicContact CD1-CD2 4.41Å; L380-L417 WeakPolarHBondContact O-CD1 3.18Å
381E98.4Very high98.1Very high4 Ų412.6 Ų12.62%0.0196%0.061CC..Hα-helixtrans-59.8-33.4178.2-68.5175.1-179.900111.5S338 R377 L383 A384 Y385 F420S338-E381 WeakPolarHBondContact CB-OE2 3.4Å; S338-E381 PolarHBondContact OG-OE2 2.72Å; R377-E381 HydrophobicContact CG-CG 4.17Å; R377-E381 WeakPolarHBondContact CG-OE1 3.39Å; R377-E381 IonicContact CZ-OE1 3.67Å; R377-E381 IonicContact NE-OE1 3.7Å; R377-E381 PolarHBondContact NE-OE1 3.24Å; R377-E381 IonicContact NH2-OE1 2.77Å; R377-E381 WeakPolarHBondContact O-CG 3.23Å; R377-E381 PolarHBondContact O-N 2.97Å; E381-L383 VanDerWaalsContact C-N 3.26Å; E381-L383 PolarHBondContact O-N 3.45Å; E381-A384 WeakPolarHBondContact O-CA 3.43Å; E381-A384 WeakPolarHBondContact O-CB 3.38Å; E381-A384 PolarHBondContact O-N 2.82Å; E381-Y385 HydrophobicContact CB-CD2 4.26Å; E381-Y385 HydrophobicContact CB-CE2 3.79Å; E381-Y385 WeakPolarHBondContact O-CD2 3.42Å; E381-Y385 PolarHBondContact O-N 3.39Å; E381-F420 HydrophobicContact CB-CD1 4.11Å; E381-F420 HydrophobicContact CB-CE1 3.61Å; E381-F420 HydrophobicContact CB-CZ 4.03Å; E381-F420 HydrophobicContact CG-CD1 3.83Å; E381-F420 HydrophobicContact CG-CD2 4.32Å; E381-F420 HydrophobicContact CG-CE1 3.63Å; E381-F420 HydrophobicContact CG-CE2 4.12Å; E381-F420 HydrophobicContact CG-CG 4.18Å; E381-F420 HydrophobicContact CG-CZ 3.78Å
382S98.4Very high98Very high1 Ų113.3 Ų13.31%0.0076%0.059CC..Hα-helixtrans-59.8-29.9175.281.70000114.8V343 A378 T379 L380 A384 Q386V343-S382 WeakPolarHBondContact O-CB 3.28Å; A378-S382 WeakPolarHBondContact O-CB 3.21Å; A378-S382 PolarHBondContact O-N 2.93Å; T379-S382 WeakPolarHBondContact O-CB 3.23Å; T379-S382 PolarHBondContact O-N 2.91Å; T379-S382 PolarHBondContact O-OG 3.48Å; L380-S382 PolarHBondContact O-N 2.8Å; S382-A384 VanDerWaalsContact C-N 3.31Å; S382-Q386 WeakPolarHBondContact O-CG 3.36Å; S382-Q386 PolarHBondContact O-N 2.85Å; S382-Q386 VanDerWaalsContact O-N 3.12Å; S382-Q386 PolarHBondContact O-NE2 3.38Å
383L97.9Very high98Very high1 Ų111 Ų111%0.0055%0.051CC..Hα-helixtrans-67.4-39.4174.2-81.762.3000110A308 A311 T379 L380 E381 T387 L417A308-L383 HydrophobicContact CB-CD2 4.02Å; A308-L383 HydrophobicContact CB-CG 3.95Å; A311-L383 HydrophobicContact CB-CD1 4.32Å; T379-L383 WeakPolarHBondContact O-CD1 3.42Å; L380-L383 WeakPolarHBondContact O-CB 3.37Å; L380-L383 PolarHBondContact O-N 2.91Å; L380-L383 VanDerWaalsContact O-N 3.09Å; E381-L383 VanDerWaalsContact C-N 3.26Å; E381-L383 PolarHBondContact O-N 3.45Å; L383-T387 WeakPolarHBondContact O-CB 3.42Å; L383-T387 PolarHBondContact O-N 3.14Å; L383-T387 VanDerWaalsContact O-N 3.14Å; L383-T387 PolarHBondContact O-OG1 3.24Å; L383-L417 HydrophobicContact CB-CD1 4.01Å; L383-L417 HydrophobicContact CD2-CD2 4.14Å
384A98.3Very high97.9Very high0 Ų09.1 Ų9.10%04%0.042CC..Hα-helixtrans-73.2-39.4-179.100000112.6E381 S382 T387 A388 L417 F420 Q421 I424E381-A384 WeakPolarHBondContact O-CA 3.43Å; E381-A384 WeakPolarHBondContact O-CB 3.38Å; E381-A384 PolarHBondContact O-N 2.82Å; S382-A384 VanDerWaalsContact C-N 3.31Å; A384-T387 PolarHBondContact O-N 3.38Å; A384-A388 WeakPolarHBondContact O-CB 3.19Å; A384-A388 PolarHBondContact O-N 2.98Å; A384-L417 HydrophobicContact CB-CD1 4.19Å; A384-F420 HydrophobicContact CB-CD1 3.56Å; A384-F420 HydrophobicContact CB-CE1 3.97Å; A384-Q421 HydrophobicContact CB-CB 4.31Å; A384-Q421 PolarHBondContact O-NE2 3.23Å; A384-I424 HydrophobicContact CB-CG2 4.17Å
385Y98.6Very high97.7Very high2 Ų210.7 Ų10.71%0.0085%0.051CC..Hα-helixtrans-63.9-46.8174.9-67.7-55.6000112.6Y342 E381 T387 A388 D389 F420 I424 L481 Y482 W485Y342-Y385 HydrophobicContact CD1-CE2 4.07Å; Y342-Y385 AromaticContact CE1-CE2 3.87Å; Y342-Y385 HydrophobicContact CE1-CE2 3.87Å; Y342-Y385 AromaticContact CE1-CZ 3.95Å; E381-Y385 HydrophobicContact CB-CD2 4.26Å; E381-Y385 HydrophobicContact CB-CE2 3.79Å; E381-Y385 WeakPolarHBondContact O-CD2 3.42Å; E381-Y385 PolarHBondContact O-N 3.39Å; Y385-T387 VanDerWaalsContact C-N 3.28Å; Y385-T387 PolarHBondContact O-N 3.02Å; Y385-A388 WeakPolarHBondContact O-CA 3.48Å; Y385-A388 WeakPolarHBondContact O-CB 3.45Å; Y385-A388 PolarHBondContact O-N 2.94Å; Y385-D389 PolarHBondContact O-N 2.92Å; Y385-F420 HydrophobicContact CE1-CE1 4.19Å; Y385-F420 HydrophobicContact CE1-CZ 4.02Å; Y385-F420 HydrophobicContact CE2-CE1 4.31Å; Y385-F420 HydrophobicContact CE2-CZ 4.33Å; Y385-F420 AromaticContact CZ-CZ 3.72Å; Y385-I424 HydrophobicContact CD1-CD1 4.05Å; Y385-I424 HydrophobicContact CD1-CG1 3.79Å; Y385-I424 HydrophobicContact CE1-CD1 3.63Å; Y385-I424 HydrophobicContact CE1-CG1 3.85Å; Y385-L481 HydrophobicContact CE1-CB 4.33Å; Y385-L481 WeakPolarHBondContact OH-CB 3.13Å; Y385-Y482 HydrophobicContact CD1-CD2 4.18Å; Y385-W485 VanDerWaalsContact CB-CE2 3.44Å; Y385-W485 HydrophobicContact CD1-CB 3.83Å; Y385-W485 AromaticContact CD1-CG 3.96Å; Y385-W485 HydrophobicContact CD1-CG 3.96Å; Y385-W485 HydrophobicContact CD2-CB 4.07Å; Y385-W485 AromaticContact CD2-CD2 3.94Å; Y385-W485 HydrophobicContact CD2-CD2 3.94Å; Y385-W485 AromaticContact CD2-CE3 3.73Å; Y385-W485 HydrophobicContact CD2-CE3 3.73Å; Y385-W485 HydrophobicContact CD2-CG 4.08Å; Y385-W485 HydrophobicContact CD2-CZ3 4.48Å; Y385-W485 HydrophobicContact CE1-CB 4.11Å; Y385-W485 HydrophobicContact CE2-CB 4.35Å; Y385-W485 HydrophobicContact CG-CB 3.83Å; Y385-W485 AromaticContact CG-CD2 3.73Å; Y385-W485 HydrophobicContact CG-CD2 3.73Å; Y385-W485 HydrophobicContact CG-CE3 4.01Å; Y385-W485 AromaticContact CG-CG 3.62Å; Y385-W485 HydrophobicContact CG-CG 3.62Å
386Q98.2Very high97.5Very high11 Ų1116.3 Ų16.35%0.0518%0.075CC..Hα-helixtrans-60.9-38.8175.8-72.9177.4104.900111.8V305 V307 S382 A388 D389 V390 W485V305-Q386 HydrophobicContact CG1-CB 3.76Å; V305-Q386 HydrophobicContact CG1-CG 4.22Å; V305-Q386 HydrophobicContact CG2-CB 3.99Å; V307-Q386 PolarHBondContact O-NE2 3.36Å; S382-Q386 WeakPolarHBondContact O-CG 3.36Å; S382-Q386 PolarHBondContact O-N 2.85Å; S382-Q386 VanDerWaalsContact O-N 3.12Å; S382-Q386 PolarHBondContact O-NE2 3.38Å; Q386-A388 VanDerWaalsContact C-N 3.33Å; Q386-D389 PolarHBondContact O-N 2.82Å; Q386-V390 PolarHBondContact O-N 3.28Å; Q386-W485 HydrophobicContact CB-CZ2 4.42Å; Q386-W485 HydrophobicContact CG-CH2 3.57Å; Q386-W485 HydrophobicContact CG-CZ2 3.44Å; Q386-W485 VanDerWaalsContact CG-CZ2 3.44Å
387T97.7Very high97.3Very high0 Ų017.4 Ų17.40%08%0.081CC..Hα-helixtrans-63.5-40.9172.8-58.70000111N262 Y264 I270 L383 A384 Y385 D389 V390 V391 L405 Q421N262-T387 WeakPolarHBondContact ND2-CG2 3.44Å; N262-T387 PolarHBondContact ND2-OG1 3Å; N262-T387 VanDerWaalsContact ND2-OG1 3.15Å; Y264-T387 PolarHBondContact OH-OG1 2.81Å; I270-T387 HydrophobicContact CD1-CG2 4.3Å; I270-T387 HydrophobicContact CG1-CG2 4.05Å; L383-T387 WeakPolarHBondContact O-CB 3.42Å; L383-T387 PolarHBondContact O-N 3.14Å; L383-T387 VanDerWaalsContact O-N 3.14Å; L383-T387 PolarHBondContact O-OG1 3.24Å; A384-T387 PolarHBondContact O-N 3.38Å; Y385-T387 VanDerWaalsContact C-N 3.28Å; Y385-T387 PolarHBondContact O-N 3.02Å; T387-D389 VanDerWaalsContact C-N 3.35Å; T387-D389 PolarHBondContact O-N 3.1Å; T387-V390 PolarHBondContact O-N 3.49Å; T387-V391 HydrophobicContact CG2-CG2 4.02Å; T387-V391 WeakPolarHBondContact O-CB 3.44Å; T387-V391 VanDerWaalsContact O-CG2 3.29Å; T387-V391 WeakPolarHBondContact O-CG2 3.43Å; T387-V391 PolarHBondContact O-N 2.91Å; T387-L405 HydrophobicContact CG2-CD2 4.06Å; T387-Q421 PolarHBondContact OG1-OE1 2.85Å
388A97.8Very high97.1Very high0 Ų016.7 Ų16.70%08%0.081CC..Hα-helixtrans-62.5-40177.100000112.4A384 Y385 Q386 V390 V391 K392 I424 L425 Y482A384-A388 WeakPolarHBondContact O-CB 3.19Å; A384-A388 PolarHBondContact O-N 2.98Å; Y385-A388 WeakPolarHBondContact O-CA 3.48Å; Y385-A388 WeakPolarHBondContact O-CB 3.45Å; Y385-A388 PolarHBondContact O-N 2.94Å; Q386-A388 VanDerWaalsContact C-N 3.33Å; A388-V390 VanDerWaalsContact C-N 3.31Å; A388-V390 PolarHBondContact O-N 3.21Å; A388-V391 PolarHBondContact O-N 3.41Å; A388-K392 VanDerWaalsContact O-CB 3.23Å; A388-K392 WeakPolarHBondContact O-CB 3.5Å; A388-K392 WeakPolarHBondContact O-CG 3.38Å; A388-K392 PolarHBondContact O-N 3.41Å; A388-I424 HydrophobicContact CB-CG1 4.4Å; A388-I424 HydrophobicContact CB-CG2 4.15Å; A388-L425 HydrophobicContact CB-CD2 3.9Å; A388-Y482 HydrophobicContact CB-CE2 4.08Å
389D97.9Very high96.8Very high2 Ų220.1 Ų20.11%0.01112%0.116CC..Hα-helixtrans-56.8-47.4174.1-61.6-25.8000111.3P353 Y354 Y385 Q386 T387 T393 Y482 W485 Q486P353-D389 HydrophobicContact CG-CB 4.18Å; Y354-D389 HydrophobicContact CE2-CB 4.42Å; Y354-D389 WeakPolarHBondContact CE2-OD2 3.47Å; Y354-D389 PolarHBondContact OH-OD2 2.92Å; Y385-D389 PolarHBondContact O-N 2.92Å; Q386-D389 PolarHBondContact O-N 2.82Å; T387-D389 VanDerWaalsContact C-N 3.35Å; T387-D389 PolarHBondContact O-N 3.1Å; D389-T393 WeakPolarHBondContact O-CB 3.42Å; D389-T393 PolarHBondContact O-N 2.6Å; D389-T393 PolarHBondContact O-OG1 3.48Å; D389-Y482 WeakPolarHBondContact OD1-CE2 3.33Å; D389-Y482 VanDerWaalsContact OD1-CZ 3.22Å; D389-Y482 PolarHBondContact OD1-OH 3.19Å; D389-W485 PolarHBondContact OD1-NE1 3.31Å; D389-W485 PolarHBondContact OD2-NE1 3.34Å; D389-Q486 PolarHBondContact OD1-NE2 3.21Å
390V97.6Very high96.3Very high0 Ų022.5 Ų22.50%013%0.131CC..Hα-helixtrans-67.8-47.5-179.9173.20000111.7I270 L285 V305 A352 Q386 T387 A388 T393 M394I270-V390 HydrophobicContact CB-CG1 3.67Å; I270-V390 HydrophobicContact CD1-CB 3.96Å; I270-V390 HydrophobicContact CD1-CG1 3.84Å; I270-V390 HydrophobicContact CD1-CG2 4.24Å; I270-V390 HydrophobicContact CG1-CB 4.18Å; I270-V390 HydrophobicContact CG1-CG1 3.77Å; I270-V390 HydrophobicContact CG2-CG1 4.24Å; L285-V390 HydrophobicContact CD2-CG1 4.08Å; V305-V390 HydrophobicContact CG2-CG2 4.01Å; A352-V390 HydrophobicContact CB-CG2 4.18Å; Q386-V390 PolarHBondContact O-N 3.28Å; T387-V390 PolarHBondContact O-N 3.49Å; A388-V390 VanDerWaalsContact C-N 3.31Å; A388-V390 PolarHBondContact O-N 3.21Å; V390-T393 CarbonylContact O-C 3.52Å; V390-T393 WeakPolarHBondContact O-CB 3.47Å; V390-T393 PolarHBondContact O-N 3.3Å; V390-M394 HydrophobicContact CG1-CE 4.02Å; V390-M394 HydrophobicContact CG1-CG 4.47Å; V390-M394 HydrophobicContact CG1-SD 4.45Å; V390-M394 WeakPolarHBondContact O-CG 3.24Å; V390-M394 PolarHBondContact O-N 3.23Å
391V97Very high96Very high2 Ų227.2 Ų27.21%0.01216%0.156CC..Hα-helixtrans-65.2-41.9-178.4171.90000111.2I270 T387 A388 T393 M394 N395 I402 L405 L425I270-V391 HydrophobicContact CG1-CG2 4.39Å; I270-V391 HydrophobicContact CG2-CG2 4.1Å; T387-V391 HydrophobicContact CG2-CG2 4.02Å; T387-V391 WeakPolarHBondContact O-CB 3.44Å; T387-V391 VanDerWaalsContact O-CG2 3.29Å; T387-V391 WeakPolarHBondContact O-CG2 3.43Å; T387-V391 PolarHBondContact O-N 2.91Å; A388-V391 PolarHBondContact O-N 3.41Å; V391-T393 VanDerWaalsContact C-N 3.3Å; V391-T393 PolarHBondContact O-N 2.84Å; V391-M394 WeakPolarHBondContact O-CB 3.44Å; V391-M394 PolarHBondContact O-N 2.9Å; V391-N395 PolarHBondContact O-N 2.98Å; V391-I402 HydrophobicContact CG1-CD1 3.79Å; V391-L405 HydrophobicContact CG2-CD2 4.45Å; V391-L425 HydrophobicContact CB-CD2 3.73Å; V391-L425 HydrophobicContact CG1-CD1 4.45Å; V391-L425 HydrophobicContact CG1-CD2 3.67Å; V391-L425 HydrophobicContact CG2-CD1 4.43Å; V391-L425 HydrophobicContact CG2-CD2 4.29Å
392K95.7Very high95.8Very high70 Ų7027.2 Ų27.230%0.30416%0.156SC..Hα-helixtrans-63.3-38.1174.4-71176.6-177.3-176.10111.2A388 N395 K396 Y482A388-K392 VanDerWaalsContact O-CB 3.23Å; A388-K392 WeakPolarHBondContact O-CB 3.5Å; A388-K392 WeakPolarHBondContact O-CG 3.38Å; A388-K392 PolarHBondContact O-N 3.41Å; K392-N395 PolarHBondContact O-N 2.98Å; K392-K396 PolarHBondContact O-N 3.07Å; K392-Y482 HydrophobicContact CD-CE1 3.85Å; K392-Y482 HydrophobicContact CD-CE2 4.47Å
393T96.7Very high95.6Very high21 Ų2133.8 Ų33.813%0.12919%0.185CC..Hα-helixtrans-66-40.7173.5-55.50000111.6N283 L285 P353 D389 V390 V391 K396 D397N283-T393 HydrophobicContact CB-CG2 3.54Å; N283-T393 WeakPolarHBondContact O-CG2 3.19Å; L285-T393 HydrophobicContact CD1-CG2 3.99Å; L285-T393 HydrophobicContact CD2-CG2 4.03Å; L285-T393 HydrophobicContact CG-CG2 3.71Å; P353-T393 HydrophobicContact CB-CG2 4.22Å; D389-T393 WeakPolarHBondContact O-CB 3.42Å; D389-T393 PolarHBondContact O-N 2.6Å; D389-T393 PolarHBondContact O-OG1 3.48Å; V390-T393 CarbonylContact O-C 3.52Å; V390-T393 WeakPolarHBondContact O-CB 3.47Å; V390-T393 PolarHBondContact O-N 3.3Å; V391-T393 VanDerWaalsContact C-N 3.3Å; V391-T393 PolarHBondContact O-N 2.84Å; T393-K396 WeakPolarHBondContact O-CB 3.45Å; T393-K396 PolarHBondContact O-N 3.2Å; T393-K396 VanDerWaalsContact O-N 3.15Å; T393-D397 PolarHBondContact O-N 3.32Å
394M96.3Very high95.6Very high0 Ų035.9 Ų35.90%020%0.196CC..Hα-helixtrans-62.6-43.2175.6-79.6-174176.400112.4V260 I270 M272 L285 L301 V390 V391 K396 D397 S398 I402V260-M394 HydrophobicContact CG1-SD 4.32Å; I270-M394 HydrophobicContact CB-CE 3.92Å; I270-M394 HydrophobicContact CB-SD 4.34Å; I270-M394 HydrophobicContact CG2-CE 3.69Å; I270-M394 HydrophobicContact CG2-SD 3.5Å; I270-M394 VanDerWaalsContact CG2-SD 3.5Å; I270-M394 WeakPolarHBondContact O-CE 3.33Å; M272-M394 HydrophobicContact CB-SD 4.02Å; M272-M394 HydrophobicContact CE-CB 4.23Å; L285-M394 HydrophobicContact CD1-CB 4.08Å; L285-M394 HydrophobicContact CD1-CG 3.35Å; L285-M394 HydrophobicContact CD2-CG 4.47Å; L301-M394 HydrophobicContact CB-CE 4.5Å; L301-M394 VanDerWaalsContact O-CE 3.3Å; L301-M394 WeakPolarHBondContact O-CE 3.41Å; V390-M394 HydrophobicContact CG1-CE 4.02Å; V390-M394 HydrophobicContact CG1-CG 4.47Å; V390-M394 HydrophobicContact CG1-SD 4.45Å; V390-M394 WeakPolarHBondContact O-CG 3.24Å; V390-M394 PolarHBondContact O-N 3.23Å; V391-M394 WeakPolarHBondContact O-CB 3.44Å; V391-M394 PolarHBondContact O-N 2.9Å; M394-K396 VanDerWaalsContact C-N 3.25Å; M394-K396 PolarHBondContact O-N 3.19Å; M394-D397 PolarHBondContact O-N 2.74Å; M394-S398 VanDerWaalsContact O-CB 3.24Å; M394-S398 WeakPolarHBondContact O-CB 3.36Å; M394-S398 PolarHBondContact O-N 3.04Å; M394-S398 PolarHBondContact O-OG 3.14Å; M394-I402 HydrophobicContact CB-CD1 4.04Å
395N94.3Very high95.5Very high47 Ų4735.9 Ų35.925%0.25120%0.196SC..Hα-helixtrans-56.2-43.2173.1-81-23.2000111V391 K392 G399 T400 I402V391-N395 PolarHBondContact O-N 2.98Å; K392-N395 PolarHBondContact O-N 2.98Å; N395-G399 WeakPolarHBondContact O-CA 3.45Å; N395-G399 PolarHBondContact O-N 3.04Å; N395-G399 VanDerWaalsContact O-N 3.08Å; N395-T400 WeakPolarHBondContact CA-O 3.21Å; N395-T400 PolarHBondContact OD1-O 3.38Å; N395-I402 WeakPolarHBondContact OD1-CB 3.5Å; N395-I402 WeakPolarHBondContact OD1-CD1 3.44Å; N395-I402 WeakPolarHBondContact OD1-CG1 3.47Å; N395-I402 PolarHBondContact OD1-N 3.18Å
396K94.9Very high95.5Very high142 Ų14238.6 Ų38.662%0.61721%0.206SC*.Hα-helixtrans-66-49.9179.3-173.1-176.6177.6-169.50112.4N283 K392 T393 M394N283-K396 WeakPolarHBondContact OD1-CE 3.26Å; N283-K396 PolarHBondContact OD1-NZ 3.23Å; K392-K396 PolarHBondContact O-N 3.07Å; T393-K396 WeakPolarHBondContact O-CB 3.45Å; T393-K396 PolarHBondContact O-N 3.2Å; T393-K396 VanDerWaalsContact O-N 3.15Å; M394-K396 VanDerWaalsContact C-N 3.25Å; M394-K396 PolarHBondContact O-N 3.19Å
397D94.1Very high95.4Very high24 Ų2438 Ų3813%0.12820%0.204CC..Hα-helixtrans-69.2-39.3-177.5-80.4-17.4000112.6I279 S281 E282 N283 L285 L301 T393 M394I279-D397 WeakPolarHBondContact CG2-O 3.36Å; S281-D397 VanDerWaalsContact CB-OD2 3.29Å; S281-D397 WeakPolarHBondContact CB-OD2 3.17Å; S281-D397 PolarHBondContact OG-OD2 2.81Å; E282-D397 PolarHBondContact N-OD1 3.24Å; N283-D397 WeakPolarHBondContact CB-OD1 3.38Å; N283-D397 PolarHBondContact ND2-OD1 3.16Å; L285-D397 HydrophobicContact CD1-CB 4.35Å; L285-D397 WeakPolarHBondContact CD1-OD2 3.4Å; L301-D397 HydrophobicContact CD1-CB 4.2Å; T393-D397 PolarHBondContact O-N 3.32Å; M394-D397 PolarHBondContact O-N 2.74Å
398S93.3Very high95.3Very high18 Ų1838 Ų3813%0.12620%0.204CC..Hα-helixtrans-84.1-16.6-177.1680000114M394 T400M394-S398 VanDerWaalsContact O-CB 3.24Å; M394-S398 WeakPolarHBondContact O-CB 3.36Å; M394-S398 PolarHBondContact O-N 3.04Å; M394-S398 PolarHBondContact O-OG 3.14Å; S398-T400 PolarHBondContact O-N 3.27Å; S398-T400 VanDerWaalsContact O-N 3.08Å; S398-T400 PolarHBondContact O-OG1 2.94Å; S398-T400 WeakPolarHBondContact OG-CB 3.39Å; S398-T400 PolarHBondContact OG-N 3.33Å; S398-T400 VanDerWaalsContact OG-N 3.13Å
399G92.4Very high94.9Very high73 Ų7338.6 Ų38.675%0.75321%0.209SC*.  trans58.715-16800000113.7N395N395-G399 WeakPolarHBondContact O-CA 3.45Å; N395-G399 PolarHBondContact O-N 3.04Å; N395-G399 VanDerWaalsContact O-N 3.08Å
400T89Confident94.4Very high51 Ų5141 Ų4131%0.31323%0.234SC..  trans-106133.5-177-57.60000109.1N395 S398 I402N395-T400 WeakPolarHBondContact CA-O 3.21Å; N395-T400 PolarHBondContact OD1-O 3.38Å; S398-T400 PolarHBondContact O-N 3.27Å; S398-T400 VanDerWaalsContact O-N 3.08Å; S398-T400 PolarHBondContact O-OG1 2.94Å; S398-T400 WeakPolarHBondContact OG-CB 3.39Å; S398-T400 PolarHBondContact OG-N 3.33Å; S398-T400 VanDerWaalsContact OG-N 3.13Å; T400-I402 PolarHBondContact O-N 2.82Å
401D91.8Very high94.2Very high102 Ų10242.1 Ų42.155%0.54524%0.244SC..  trans-84.6101.9177.3-174.1-12.9000109.5K403D401-K403 VanDerWaalsContact CG-CE 3.42Å; D401-K403 PolarHBondContact O-N 3.4Å; D401-K403 VanDerWaalsContact O-N 3.16Å; D401-K403 WeakPolarHBondContact OD1-CE 3.34Å; D401-K403 IonicContact OD1-NZ 2.74Å; D401-K403 PolarHBondContact OD1-NZ 2.99Å; D401-K403 VanDerWaalsContact OD2-CE 3.27Å; D401-K403 WeakPolarHBondContact OD2-CE 3.35Å; D401-K403 IonicContact OD2-NZ 3.67Å; D401-K403 PolarHBondContact OD2-NZ 3.42Å
402I94.3Very high94Very high4 Ų442 Ų422%0.02124%0.243CC..  trans-65.6112-179.4-65.3162000109.7V260 M272 V391 M394 N395 T400 T427V260-I402 HydrophobicContact CB-CG2 4.39Å; V260-I402 HydrophobicContact CG2-CD1 3.94Å; V260-I402 HydrophobicContact CG2-CG1 3.81Å; V260-I402 HydrophobicContact CG2-CG2 4.06Å; M272-I402 HydrophobicContact CE-CD1 3.43Å; M272-I402 VanDerWaalsContact CE-CD1 3.43Å; M272-I402 HydrophobicContact CE-CG1 3.43Å; M272-I402 VanDerWaalsContact CE-CG1 3.43Å; V391-I402 HydrophobicContact CG1-CD1 3.79Å; M394-I402 HydrophobicContact CB-CD1 4.04Å; N395-I402 WeakPolarHBondContact OD1-CB 3.5Å; N395-I402 WeakPolarHBondContact OD1-CD1 3.44Å; N395-I402 WeakPolarHBondContact OD1-CG1 3.47Å; N395-I402 PolarHBondContact OD1-N 3.18Å; T400-I402 PolarHBondContact O-N 2.82Å; I402-T427 VanDerWaalsContact O-CG2 3.31Å; I402-T427 WeakPolarHBondContact O-CG2 3.17Å
403K94.4Very high93.9Very high139 Ų13944.8 Ų44.860%0.60426%0.255SS*.  trans-92.8-12.5-177.6-62.9-49.1-172.1-172.10115.6D401 P428D401-K403 VanDerWaalsContact CG-CE 3.42Å; D401-K403 PolarHBondContact O-N 3.4Å; D401-K403 VanDerWaalsContact O-N 3.16Å; D401-K403 WeakPolarHBondContact OD1-CE 3.34Å; D401-K403 IonicContact OD1-NZ 2.74Å; D401-K403 PolarHBondContact OD1-NZ 2.99Å; D401-K403 VanDerWaalsContact OD2-CE 3.27Å; D401-K403 WeakPolarHBondContact OD2-CE 3.35Å; D401-K403 IonicContact OD2-NZ 3.67Å; D401-K403 PolarHBondContact OD2-NZ 3.42Å; K403-P428 WeakPolarHBondContact O-CD 3.46Å
404L96.6Very high93.9Very high46 Ų4644.4 Ų44.424%0.24125%0.253CS..  trans-155.8130-177.5-179.965.2000108.4R406 P428 E430L404-R406 HydrophobicContact CD2-CG 4.31Å; L404-R406 HydrophobicContact CG-CG 4.47Å; L404-P428 HydrophobicContact CD1-CB 3.97Å; L404-E430 HydrophobicContact CD1-CB 3.86Å
405L97.6Very high93.9Very high0 Ų047.1 Ų47.10%027%0.267CS..EExtended strand (participates in β ladder)trans-104.6112.5167.6-17964.8000109.3V260 N262 T387 V391 V407 Q421 L425 P428 V429 E430V260-L405 HydrophobicContact CB-CD1 4.34Å; V260-L405 HydrophobicContact CG1-CD1 3.81Å; N262-L405 HydrophobicContact CB-CD1 4.08Å; N262-L405 HydrophobicContact CB-CD2 4.36Å; N262-L405 HydrophobicContact CB-CG 4.46Å; T387-L405 HydrophobicContact CG2-CD2 4.06Å; V391-L405 HydrophobicContact CG2-CD2 4.45Å; L405-V407 HydrophobicContact CD2-CG1 4.16Å; L405-V407 HydrophobicContact CG-CG1 3.98Å; L405-Q421 HydrophobicContact CD2-CG 4.28Å; L405-L425 HydrophobicContact CD2-CD1 3.6Å; L405-P428 PolarHBondContact N-O 3.17Å; L405-V429 HydrophobicContact CB-CG2 4.37Å; L405-V429 WeakPolarHBondContact O-CA 3.28Å; L405-E430 PolarHBondContact O-N 3.02Å
406R97.4Very high94.1Very high58 Ų5845.7 Ų45.722%0.21926%0.259CS..EExtended strand (participates in β ladder)trans-79.2141.7169.9-70.7-173.7171.3163.86.1110.3Q252 V260 K261 N262 L404 E430Q252-R406 PolarHBondContact O-NH1 3.32Å; V260-R406 PolarHBondContact O-N 3.47Å; V260-R406 VanDerWaalsContact O-N 3.14Å; K261-R406 CarbonylContact C-O 3.59Å; K261-R406 WeakPolarHBondContact CA-O 3.18Å; K261-R406 HydrophobicContact CB-CB 4.34Å; N262-R406 PolarHBondContact N-O 3.16Å; L404-R406 HydrophobicContact CD2-CG 4.31Å; L404-R406 HydrophobicContact CG-CG 4.47Å; R406-E430 CarbonylContact C-O 3.57Å; R406-E430 WeakPolarHBondContact CA-O 3.46Å; R406-E430 IonicContact CZ-OE1 2.71Å; R406-E430 IonicContact NE-OE1 2.94Å; R406-E430 PolarHBondContact NE-OE1 2.96Å; R406-E430 VanDerWaalsContact NE-OE1 3.13Å; R406-E430 IonicContact NH2-OE1 2.56Å
407V97.4Very high94.2Very high0 Ų039 Ų390%023%0.23CC..EExtended strand (participates in β ladder)trans-133145.9-177.2-56.60000111.8Q252 N262 Y264 L405 L418 V429 E430 R431 A432Q252-V407 PolarHBondContact NE2-O 2.8Å; N262-V407 HydrophobicContact CB-CG1 4.38Å; N262-V407 VanDerWaalsContact O-CA 3.27Å; N262-V407 WeakPolarHBondContact O-CA 3.3Å; Y264-V407 HydrophobicContact CD2-CB 4.2Å; Y264-V407 HydrophobicContact CD2-CG1 4.46Å; Y264-V407 HydrophobicContact CE2-CB 3.93Å; Y264-V407 HydrophobicContact CE2-CG1 3.71Å; L405-V407 HydrophobicContact CD2-CG1 4.16Å; L405-V407 HydrophobicContact CG-CG1 3.98Å; V407-L418 HydrophobicContact CB-CD2 4.47Å; V407-L418 HydrophobicContact CG2-CD1 3.83Å; V407-L418 HydrophobicContact CG2-CD2 3.79Å; V407-L418 HydrophobicContact CG2-CG 4.49Å; V407-V429 HydrophobicContact CB-CG1 4.35Å; V407-V429 HydrophobicContact CG1-CG1 3.63Å; V407-V429 HydrophobicContact CG2-CG1 3.72Å; V407-E430 PolarHBondContact N-O 2.86Å; V407-R431 HydrophobicContact CG2-CB 4.01Å; V407-A432 PolarHBondContact O-N 2.8Å
408D94.8Very high94.4Very high0 Ų037.9 Ų37.90%022%0.224CC..EExtended strand (participates in β ladder)trans-146.9-172.1174.757.159.7000110.8Q252 N262 T263 Y264 A432 T437Q252-D408 WeakPolarHBondContact CG-OD2 3.47Å; Q252-D408 PolarHBondContact NE2-OD2 2.72Å; N262-D408 PolarHBondContact O-N 2.92Å; N262-D408 VanDerWaalsContact O-N 3.1Å; T263-D408 WeakPolarHBondContact CA-OD1 3.2Å; T263-D408 WeakPolarHBondContact CB-OD1 3.38Å; T263-D408 WeakPolarHBondContact CG2-OD1 3.27Å; T263-D408 PolarHBondContact OG1-OD1 2.6Å; Y264-D408 PolarHBondContact N-O 2.95Å; D408-A432 HydrophobicContact CB-CB 4.17Å; D408-T437 HydrophobicContact CB-CG2 3.75Å; D408-T437 PolarHBondContact OD1-OG1 2.67Å; D408-T437 PolarHBondContact OD2-OG1 3.03Å
409G89.2Confident94.7Very high12 Ų1239.8 Ų39.812%0.12423%0.231CC..SBendtrans86.3165.6-179.100000114.1Y264 A411 S412 L435Y264-G409 CarbonylContact O-C 3.6Å; Y264-G409 VanDerWaalsContact O-C 3.29Å; G409-A411 PolarHBondContact O-N 3.31Å; G409-S412 WeakPolarHBondContact O-CB 3.39Å; G409-S412 PolarHBondContact O-N 3.47Å; G409-S412 VanDerWaalsContact O-N 3.16Å; G409-S412 PolarHBondContact O-OG 3.38Å; G409-L435 PolarHBondContact N-O 3.21Å
410G88.3Confident95Very high52 Ų5236.7 Ų36.754%0.53620%0.197SC..G310 helixtrans-62.4-36.7-167.900000114.9Y264 S412 K413Y264-G410 PolarHBondContact O-N 3.48Å; Y264-G410 VanDerWaalsContact O-N 3.11Å; G410-S412 VanDerWaalsContact C-N 3.29Å; G410-S412 PolarHBondContact O-N 3.21Å; G410-K413 WeakPolarHBondContact O-CB 3.4Å; G410-K413 WeakPolarHBondContact O-CG 3.49Å; G410-K413 PolarHBondContact O-N 2.95Å
411A91.8Very high95.4Very high24 Ų2434.2 Ų34.220%0.19818%0.182CC..G310 helixtrans-77.1-15.3-179.300000113.2Y264 G409 K413 N414Y264-A411 PolarHBondContact O-N 2.77Å; G409-A411 PolarHBondContact O-N 3.31Å; A411-K413 PolarHBondContact O-N 2.99Å; A411-K413 VanDerWaalsContact O-N 3.16Å; A411-N414 WeakPolarHBondContact O-CB 3.43Å; A411-N414 PolarHBondContact O-N 3.25Å
412S93.5Very high95.7Very high0 Ų029.4 Ų29.40%016%0.156CC..G310 helixtrans-67.1-9.9171.676.90000113.3G409 G410 N414 L418 R431 L435G409-S412 WeakPolarHBondContact O-CB 3.39Å; G409-S412 PolarHBondContact O-N 3.47Å; G409-S412 VanDerWaalsContact O-N 3.16Å; G409-S412 PolarHBondContact O-OG 3.38Å; G410-S412 VanDerWaalsContact C-N 3.29Å; G410-S412 PolarHBondContact O-N 3.21Å; S412-N414 PolarHBondContact O-N 3.16Å; S412-L418 WeakPolarHBondContact O-CD1 3.2Å; S412-R431 WeakPolarHBondContact O-CD 3.33Å; S412-R431 PolarHBondContact O-NH1 3.35Å; S412-L435 WeakPolarHBondContact OG-CD2 3.37Å
413K93.7Very high95.9Very high128 Ų12829.8 Ų29.856%0.55716%0.158SC*.G310 helixtrans-65.9-15.4171.5-68.8-176.1179.2179.60113.6G410 A411 D415 R431 L435G410-K413 WeakPolarHBondContact O-CB 3.4Å; G410-K413 WeakPolarHBondContact O-CG 3.49Å; G410-K413 PolarHBondContact O-N 2.95Å; A411-K413 PolarHBondContact O-N 2.99Å; A411-K413 VanDerWaalsContact O-N 3.16Å; K413-D415 PolarHBondContact O-N 3.23Å; K413-R431 PolarHBondContact O-NH1 2.84Å; K413-L435 HydrophobicContact CD-CD1 3.98Å; K413-L435 HydrophobicContact CG-CD1 3.51Å
414N96.3Very high96.1Very high13 Ų1323.4 Ų23.47%0.0713%0.13CC..  trans-84.4109.8-179.6-176.2-37.4000110.3L380 A411 S412 L416 L417 L418L380-N414 WeakPolarHBondContact CD1-ND2 3.42Å; L380-N414 WeakPolarHBondContact CD2-ND2 3.4Å; A411-N414 WeakPolarHBondContact O-CB 3.43Å; A411-N414 PolarHBondContact O-N 3.25Å; S412-N414 PolarHBondContact O-N 3.16Å; N414-L416 VanDerWaalsContact C-N 3.35Å; N414-L416 PolarHBondContact O-N 2.81Å; N414-L416 WeakPolarHBondContact OD1-CB 3.38Å; N414-L416 PolarHBondContact OD1-N 2.79Å; N414-L416 VanDerWaalsContact OD1-N 3.1Å; N414-L417 HydrophobicContact CB-CB 3.93Å; N414-L417 PolarHBondContact O-N 3.4Å; N414-L417 PolarHBondContact OD1-N 3.37Å; N414-L418 PolarHBondContact O-N 3.27Å
415D97.5Very high96.2Very high56 Ų5622 Ų2230%0.29912%0.123SC..Hα-helixtrans-70.3-31.6-175.3-68.1-21.1000112.2E329 K413 L418 Q419 R431 Y469E329-D415 PolarHBondContact OE1-N 2.92Å; K413-D415 PolarHBondContact O-N 3.23Å; D415-L418 PolarHBondContact O-N 2.79Å; D415-Q419 WeakPolarHBondContact O-CB 3.3Å; D415-Q419 PolarHBondContact O-N 2.56Å; D415-R431 IonicContact OD1-CZ 3.45Å; D415-R431 IonicContact OD1-NH1 3.55Å; D415-R431 PolarHBondContact OD1-NH1 3.47Å; D415-R431 IonicContact OD1-NH2 3.59Å; D415-R431 PolarHBondContact OD1-NH2 2.98Å; D415-Y469 HydrophobicContact CB-CE1 4.18Å; D415-Y469 PolarHBondContact OD1-OH 3.07Å
416L97.5Very high96.1Very high18 Ų1825.2 Ų25.29%0.09414%0.138CC..Hα-helixtrans-63.7-43.4174.1178.9153.6000111E329 A332 K333 L380 N414 F420E329-L416 HydrophobicContact CG-CB 4.3Å; A332-L416 HydrophobicContact CB-CD1 3.97Å; A332-L416 HydrophobicContact CB-CD2 4.37Å; K333-L416 HydrophobicContact CB-CD1 4.47Å; K333-L416 HydrophobicContact CG-CD1 3.56Å; L380-L416 HydrophobicContact CD1-CD2 4.41Å; N414-L416 VanDerWaalsContact C-N 3.35Å; N414-L416 PolarHBondContact O-N 2.81Å; N414-L416 WeakPolarHBondContact OD1-CB 3.38Å; N414-L416 PolarHBondContact OD1-N 2.79Å; N414-L416 VanDerWaalsContact OD1-N 3.1Å; L416-F420 VanDerWaalsContact O-CB 3.32Å; L416-F420 WeakPolarHBondContact O-CB 3.36Å; L416-F420 PolarHBondContact O-N 3.11Å
417L97.9Very high96.1Very high2 Ų223.1 Ų23.11%0.0113%0.132CC..Hα-helixtrans-60.3-47.3176.6172.263.6000110.8Y264 L380 L383 A384 N414 F420 Q421Y264-L417 HydrophobicContact CD1-CD2 4.4Å; L380-L417 WeakPolarHBondContact O-CD1 3.18Å; L383-L417 HydrophobicContact CB-CD1 4.01Å; L383-L417 HydrophobicContact CD2-CD2 4.14Å; A384-L417 HydrophobicContact CB-CD1 4.19Å; N414-L417 HydrophobicContact CB-CB 3.93Å; N414-L417 PolarHBondContact O-N 3.4Å; N414-L417 PolarHBondContact OD1-N 3.37Å; L417-F420 PolarHBondContact O-N 3.14Å; L417-Q421 WeakPolarHBondContact O-CB 3.43Å; L417-Q421 PolarHBondContact O-N 2.93Å
418L98.2Very high96.2Very high0 Ų024.1 Ų24.10%014%0.139CC..Hα-helixtrans-70.3-37-176.8-66.2-165.5000113.2Y264 V407 S412 N414 D415 Q421 A422 V429 R431 Y469Y264-L418 HydrophobicContact CE2-CD2 4.29Å; V407-L418 HydrophobicContact CB-CD2 4.47Å; V407-L418 HydrophobicContact CG2-CD1 3.83Å; V407-L418 HydrophobicContact CG2-CD2 3.79Å; V407-L418 HydrophobicContact CG2-CG 4.49Å; S412-L418 WeakPolarHBondContact O-CD1 3.2Å; N414-L418 PolarHBondContact O-N 3.27Å; D415-L418 PolarHBondContact O-N 2.79Å; L418-Q421 PolarHBondContact O-N 3.24Å; L418-A422 PolarHBondContact O-N 3.45Å; L418-V429 HydrophobicContact CD2-CG1 4.33Å; L418-R431 HydrophobicContact CD1-CB 3.78Å; L418-R431 HydrophobicContact CD1-CG 4.22Å; L418-Y469 HydrophobicContact CB-CD1 4.16Å; L418-Y469 HydrophobicContact CB-CD2 3.88Å; L418-Y469 HydrophobicContact CB-CE1 4.04Å; L418-Y469 HydrophobicContact CB-CE2 3.8Å; L418-Y469 HydrophobicContact CB-CG 4.08Å; L418-Y469 HydrophobicContact CD1-CD2 4.15Å; L418-Y469 HydrophobicContact CD1-CE2 3.5Å; L418-Y469 VanDerWaalsContact CD1-CE2 3.5Å; L418-Y469 HydrophobicContact CG-CE2 4.32Å
419Q98.6Very high96.3Very high58 Ų5824.1 Ų24.127%0.27114%0.139SC..Hα-helixtrans-62.1-48.8171.8-176.258.757.200110.7D415 Q421 A422 D423 Y469 E470D415-Q419 WeakPolarHBondContact O-CB 3.3Å; D415-Q419 PolarHBondContact O-N 2.56Å; Q419-Q421 VanDerWaalsContact C-N 3.27Å; Q419-Q421 PolarHBondContact O-N 3.49Å; Q419-A422 PolarHBondContact O-N 3.25Å; Q419-A422 VanDerWaalsContact O-N 3.14Å; Q419-D423 PolarHBondContact NE2-OD1 3.07Å; Q419-D423 PolarHBondContact O-N 2.73Å; Q419-Y469 HydrophobicContact CB-CD1 4.27Å; Q419-E470 PolarHBondContact NE2-O 3.13Å
420F98.4Very high96.7Very high7 Ų724.6 Ų24.63%0.03114%0.138CC..Hα-helixtrans-63.9-33178.2-172.6-99.3000112.4E381 A384 Y385 L416 L417 D423 I424 M473 L481E381-F420 HydrophobicContact CB-CD1 4.11Å; E381-F420 HydrophobicContact CB-CE1 3.61Å; E381-F420 HydrophobicContact CB-CZ 4.03Å; E381-F420 HydrophobicContact CG-CD1 3.83Å; E381-F420 HydrophobicContact CG-CD2 4.32Å; E381-F420 HydrophobicContact CG-CE1 3.63Å; E381-F420 HydrophobicContact CG-CE2 4.12Å; E381-F420 HydrophobicContact CG-CG 4.18Å; E381-F420 HydrophobicContact CG-CZ 3.78Å; A384-F420 HydrophobicContact CB-CD1 3.56Å; A384-F420 HydrophobicContact CB-CE1 3.97Å; Y385-F420 HydrophobicContact CE1-CE1 4.19Å; Y385-F420 HydrophobicContact CE1-CZ 4.02Å; Y385-F420 HydrophobicContact CE2-CE1 4.31Å; Y385-F420 HydrophobicContact CE2-CZ 4.33Å; Y385-F420 AromaticContact CZ-CZ 3.72Å; L416-F420 VanDerWaalsContact O-CB 3.32Å; L416-F420 WeakPolarHBondContact O-CB 3.36Å; L416-F420 PolarHBondContact O-N 3.11Å; L417-F420 PolarHBondContact O-N 3.14Å; F420-D423 PolarHBondContact O-N 3.44Å; F420-I424 HydrophobicContact CE1-CB 4.43Å; F420-I424 WeakPolarHBondContact O-CB 3.32Å; F420-I424 WeakPolarHBondContact O-CG2 3.42Å; F420-I424 PolarHBondContact O-N 3.12Å; F420-M473 HydrophobicContact CD2-CE 4.15Å; F420-M473 HydrophobicContact CE2-CE 4.08Å; F420-L481 HydrophobicContact CE2-CD1 4.16Å; F420-L481 HydrophobicContact CZ-CD1 4.44Å
421Q98.6Very high97.2Very high0 Ų023.9 Ų23.90%012%0.119CC..Hα-helixtrans-63.5-43.4173.4-177.165.781.500112.2Y264 A384 T387 L405 L417 L418 Q419 L425 V429Y264-Q421 VanDerWaalsContact OH-CD 3.29Å; Y264-Q421 WeakPolarHBondContact OH-CG 3.49Å; Y264-Q421 PolarHBondContact OH-OE1 3.27Å; A384-Q421 HydrophobicContact CB-CB 4.31Å; A384-Q421 PolarHBondContact O-NE2 3.23Å; T387-Q421 PolarHBondContact OG1-OE1 2.85Å; L405-Q421 HydrophobicContact CD2-CG 4.28Å; L417-Q421 WeakPolarHBondContact O-CB 3.43Å; L417-Q421 PolarHBondContact O-N 2.93Å; L418-Q421 PolarHBondContact O-N 3.24Å; Q419-Q421 VanDerWaalsContact C-N 3.27Å; Q419-Q421 PolarHBondContact O-N 3.49Å; Q421-L425 HydrophobicContact CG-CD1 4.05Å; Q421-L425 VanDerWaalsContact NE2-CD1 3.28Å; Q421-L425 VanDerWaalsContact NE2-CG 3.33Å; Q421-L425 WeakPolarHBondContact O-CB 3.19Å; Q421-L425 WeakPolarHBondContact O-CG 2.97Å; Q421-L425 PolarHBondContact O-N 3.22Å; Q421-V429 HydrophobicContact CB-CG2 4.33Å; Q421-V429 HydrophobicContact CG-CG2 3.94Å
422A98.6Very high97.3Very high0 Ų023.1 Ų23.10%011%0.112CC..Hα-helixtrans-64.6-43.3175.800000110.8L418 Q419 L425 Q426 T427 V429L418-A422 PolarHBondContact O-N 3.45Å; Q419-A422 PolarHBondContact O-N 3.25Å; Q419-A422 VanDerWaalsContact O-N 3.14Å; A422-L425 PolarHBondContact O-N 3.41Å; A422-Q426 WeakPolarHBondContact O-CA 3.3Å; A422-Q426 PolarHBondContact O-N 2.92Å; A422-T427 WeakPolarHBondContact CA-O 3.3Å; A422-T427 PolarHBondContact O-N 2.62Å; A422-V429 HydrophobicContact CB-CB 4.13Å; A422-V429 HydrophobicContact CB-CG2 3.77Å
423D98.4Very high97.1Very high13 Ų1327.2 Ų27.27%0.0714%0.139CC..Hα-helixtrans-57.9-56.1176.7-66.1-23.5000111.5Q419 F420 L425 Q426 A472 M473 T478Q419-D423 PolarHBondContact NE2-OD1 3.07Å; Q419-D423 PolarHBondContact O-N 2.73Å; F420-D423 PolarHBondContact O-N 3.44Å; D423-L425 VanDerWaalsContact C-N 3.27Å; D423-L425 PolarHBondContact O-N 2.85Å; D423-Q426 WeakPolarHBondContact O-CG 3.3Å; D423-Q426 PolarHBondContact O-N 2.98Å; D423-Q426 VanDerWaalsContact O-N 3.1Å; D423-Q426 PolarHBondContact O-NE2 3.25Å; D423-A472 PolarHBondContact OD1-N 3.41Å; D423-M473 HydrophobicContact CB-CB 3.72Å; D423-M473 HydrophobicContact CB-CE 4.33Å; D423-M473 PolarHBondContact OD1-N 2.9Å; D423-T478 WeakPolarHBondContact O-CG2 3.29Å
424I98.2Very high96.9Very high4 Ų423.6 Ų23.62%0.02112%0.122CC..Hα-helixtrans-68.8-24.8-174.5-161.160.2000113.6A384 Y385 A388 F420 L481 Y482A384-I424 HydrophobicContact CB-CG2 4.17Å; Y385-I424 HydrophobicContact CD1-CD1 4.05Å; Y385-I424 HydrophobicContact CD1-CG1 3.79Å; Y385-I424 HydrophobicContact CE1-CD1 3.63Å; Y385-I424 HydrophobicContact CE1-CG1 3.85Å; A388-I424 HydrophobicContact CB-CG1 4.4Å; A388-I424 HydrophobicContact CB-CG2 4.15Å; F420-I424 HydrophobicContact CE1-CB 4.43Å; F420-I424 WeakPolarHBondContact O-CB 3.32Å; F420-I424 WeakPolarHBondContact O-CG2 3.42Å; F420-I424 PolarHBondContact O-N 3.12Å; I424-L481 HydrophobicContact CD1-CB 4.49Å; I424-Y482 HydrophobicContact CG1-CD2 4.47Å
425L97.4Very high96.5Very high18 Ų1824.1 Ų24.19%0.09413%0.125CC..Hα-helixtrans-87-17.7174.3-74.6176.2000113.5A388 V391 L405 Q421 A422 D423 T427A388-L425 HydrophobicContact CB-CD2 3.9Å; V391-L425 HydrophobicContact CB-CD2 3.73Å; V391-L425 HydrophobicContact CG1-CD1 4.45Å; V391-L425 HydrophobicContact CG1-CD2 3.67Å; V391-L425 HydrophobicContact CG2-CD1 4.43Å; V391-L425 HydrophobicContact CG2-CD2 4.29Å; L405-L425 HydrophobicContact CD2-CD1 3.6Å; Q421-L425 HydrophobicContact CG-CD1 4.05Å; Q421-L425 VanDerWaalsContact NE2-CD1 3.28Å; Q421-L425 VanDerWaalsContact NE2-CG 3.33Å; Q421-L425 WeakPolarHBondContact O-CB 3.19Å; Q421-L425 WeakPolarHBondContact O-CG 2.97Å; Q421-L425 PolarHBondContact O-N 3.22Å; A422-L425 PolarHBondContact O-N 3.41Å; D423-L425 VanDerWaalsContact C-N 3.27Å; D423-L425 PolarHBondContact O-N 2.85Å; L425-T427 PolarHBondContact O-N 3.1Å; L425-T427 VanDerWaalsContact O-N 3.15Å; L425-T427 PolarHBondContact O-OG1 3.05Å
426Q97.5Very high96.2Very high66 Ų6624 Ų2431%0.30812%0.122SC..THydrogen-bonded Turntrans50.635.6-168.6-64-74.2-48.700111.9A422 D423 P471 M473A422-Q426 WeakPolarHBondContact O-CA 3.3Å; A422-Q426 PolarHBondContact O-N 2.92Å; D423-Q426 WeakPolarHBondContact O-CG 3.3Å; D423-Q426 PolarHBondContact O-N 2.98Å; D423-Q426 VanDerWaalsContact O-N 3.1Å; D423-Q426 PolarHBondContact O-NE2 3.25Å; Q426-P471 VanDerWaalsContact C-CG 3.49Å; Q426-M473 PolarHBondContact NE2-O 3.09Å
427T97.2Very high96Very high15 Ų1523.2 Ų23.29%0.09212%0.119CC..SBendtrans-138.7137-175.3-580000108.8I402 A422 L425 V429I402-T427 VanDerWaalsContact O-CG2 3.31Å; I402-T427 WeakPolarHBondContact O-CG2 3.17Å; A422-T427 WeakPolarHBondContact CA-O 3.3Å; A422-T427 PolarHBondContact O-N 2.62Å; L425-T427 PolarHBondContact O-N 3.1Å; L425-T427 VanDerWaalsContact O-N 3.15Å; L425-T427 PolarHBondContact O-OG1 3.05Å; T427-V429 PolarHBondContact O-N 3.27Å
428P97.9Very high95.9Very high21 Ų2123.8 Ų23.814%0.13612%0.122CC..  trans-55140.1175.2-22.830.1000112.6K403 L404 L405 Y469 E470K403-P428 WeakPolarHBondContact O-CD 3.46Å; L404-P428 HydrophobicContact CD1-CB 3.97Å; L405-P428 PolarHBondContact N-O 3.17Å; P428-Y469 WeakPolarHBondContact CA-O 3.42Å; P428-E470 WeakPolarHBondContact CG-OE2 3.32Å
429V98.3Very high95.8Very high0 Ų023.8 Ų23.80%012%0.122CC..EExtended strand (participates in β ladder)trans-116131.1175174.70000109.1L405 V407 L418 Q421 A422 T427 R468 Y469L405-V429 HydrophobicContact CB-CG2 4.37Å; L405-V429 WeakPolarHBondContact O-CA 3.28Å; V407-V429 HydrophobicContact CB-CG1 4.35Å; V407-V429 HydrophobicContact CG1-CG1 3.63Å; V407-V429 HydrophobicContact CG2-CG1 3.72Å; L418-V429 HydrophobicContact CD2-CG1 4.33Å; Q421-V429 HydrophobicContact CB-CG2 4.33Å; Q421-V429 HydrophobicContact CG-CG2 3.94Å; A422-V429 HydrophobicContact CB-CB 4.13Å; A422-V429 HydrophobicContact CB-CG2 3.77Å; T427-V429 PolarHBondContact O-N 3.27Å; V429-R468 CarbonylContact O-C 3.59Å; V429-R468 WeakPolarHBondContact O-CA 3.44Å; V429-Y469 PolarHBondContact N-O 3.02Å; V429-Y469 PolarHBondContact O-N 3.43Å
430E97.5Very high95.7Very high22 Ų2221.7 Ų21.710%0.10311%0.113CC..EExtended strand (participates in β ladder)trans-122.1114.6-178.9177.4176.184.200110.6L404 L405 R406 V407L404-E430 HydrophobicContact CD1-CB 3.86Å; L405-E430 PolarHBondContact O-N 3.02Å; R406-E430 CarbonylContact C-O 3.57Å; R406-E430 WeakPolarHBondContact CA-O 3.46Å; R406-E430 IonicContact CZ-OE1 2.71Å; R406-E430 IonicContact NE-OE1 2.94Å; R406-E430 PolarHBondContact NE-OE1 2.96Å; R406-E430 VanDerWaalsContact NE-OE1 3.13Å; R406-E430 IonicContact NH2-OE1 2.56Å; V407-E430 PolarHBondContact N-O 2.86Å
431R97.3Very high95.6Very high36 Ų3621.3 Ų21.314%0.13611%0.111CC..EExtended strand (participates in β ladder)trans-80.2125.8177.5177.216667.2-160.70.5110.7V407 S412 K413 D415 L418 L435 G466 Q467 Y469V407-R431 HydrophobicContact CG2-CB 4.01Å; S412-R431 WeakPolarHBondContact O-CD 3.33Å; S412-R431 PolarHBondContact O-NH1 3.35Å; K413-R431 PolarHBondContact O-NH1 2.84Å; D415-R431 IonicContact OD1-CZ 3.45Å; D415-R431 IonicContact OD1-NH1 3.55Å; D415-R431 PolarHBondContact OD1-NH1 3.47Å; D415-R431 IonicContact OD1-NH2 3.59Å; D415-R431 PolarHBondContact OD1-NH2 2.98Å; L418-R431 HydrophobicContact CD1-CB 3.78Å; L418-R431 HydrophobicContact CD1-CG 4.22Å; R431-L435 HydrophobicContact CG-CD2 3.82Å; R431-G466 WeakPolarHBondContact O-CA 3.47Å; R431-Q467 PolarHBondContact N-O 3.3Å; R431-Q467 PolarHBondContact O-N 3.18Å; R431-Y469 HydrophobicContact CB-CE2 4.26Å; R431-Y469 PolarHBondContact NH1-OH 2.87Å; R431-Y469 PolarHBondContact NH2-OH 3.38Å; R431-Y469 VanDerWaalsContact NH2-OH 3.09Å
432A94.1Very high95.6Very high8 Ų821.3 Ų21.37%0.06611%0.111CC..  trans-54.7138.3176.400000111.7V407 D408 Y434 L435 T437V407-A432 PolarHBondContact O-N 2.8Å; D408-A432 HydrophobicContact CB-CB 4.17Å; A432-Y434 VanDerWaalsContact C-N 3.25Å; A432-Y434 VanDerWaalsContact CB-O 3.26Å; A432-Y434 WeakPolarHBondContact CB-O 3.21Å; A432-Y434 PolarHBondContact O-N 3.11Å; A432-L435 WeakPolarHBondContact O-CD2 3.5Å; A432-T437 HydrophobicContact CB-CG2 3.79Å
433P90.3Very high95.6Very high87 Ų8721.3 Ų21.357%0.56511%0.111SC*.SBendtrans-64.3-32.5178.127.7-37.1000112.2S464P433-S464 VanDerWaalsContact CG-OG 3.26Å; P433-S464 WeakPolarHBondContact CG-OG 3.21Å
434Y89.9Confident95.6Very high52 Ų5221.1 Ų21.120%0.20411%0.109CC..SBendtrans-115.2126.3170.9-175.7-112.6000108.3I18 F20 E26 A432 E436 T437 L440I18-Y434 WeakPolarHBondContact CD1-OH 3.38Å; F20-Y434 AromaticContact CE1-CE1 3.83Å; F20-Y434 HydrophobicContact CE1-CE1 3.83Å; F20-Y434 AromaticContact CE1-CZ 3.98Å; F20-Y434 AromaticContact CZ-CE1 3.96Å; F20-Y434 HydrophobicContact CZ-CE1 3.96Å; E26-Y434 HydrophobicContact CB-CE2 4.27Å; E26-Y434 VanDerWaalsContact OE2-CE2 3.3Å; E26-Y434 WeakPolarHBondContact OE2-CE2 2.96Å; E26-Y434 PolarHBondContact OE2-OH 2.97Å; A432-Y434 VanDerWaalsContact C-N 3.25Å; A432-Y434 VanDerWaalsContact CB-O 3.26Å; A432-Y434 WeakPolarHBondContact CB-O 3.21Å; A432-Y434 PolarHBondContact O-N 3.11Å; Y434-E436 HydrophobicContact CD1-CB 4.27Å; Y434-E436 HydrophobicContact CE1-CB 3.54Å; Y434-E436 WeakPolarHBondContact CE1-O 3.27Å; Y434-E436 HydrophobicContact CE2-CB 4.45Å; Y434-T437 VanDerWaalsContact O-CG2 3.24Å; Y434-T437 WeakPolarHBondContact O-CG2 3.29Å; Y434-L440 HydrophobicContact CD1-CB 4.29Å; Y434-L440 HydrophobicContact CD1-CD2 4.11Å; Y434-L440 HydrophobicContact CE1-CB 4.29Å
435L87.9Confident95.6Very high23 Ų2320.9 Ų20.912%0.1211%0.108CC..SBendtrans-90.1-18.3-166.7-62.6175.7000113.2G409 S412 K413 R431 A432 T437G409-L435 PolarHBondContact N-O 3.21Å; S412-L435 WeakPolarHBondContact OG-CD2 3.37Å; K413-L435 HydrophobicContact CD-CD1 3.98Å; K413-L435 HydrophobicContact CG-CD1 3.51Å; R431-L435 HydrophobicContact CG-CD2 3.82Å; A432-L435 WeakPolarHBondContact O-CD2 3.5Å; L435-T437 PolarHBondContact O-N 3.1Å; L435-T437 VanDerWaalsContact O-N 3.11Å
436E89.7Confident95.7Very high53 Ų5320 Ų2025%0.24810%0.104CC..  trans-87.646.9179.1-65.466.3-159.800109.8I18 Y434 T438 A439 L440I18-E436 HydrophobicContact CD1-CB 4.2Å; I18-E436 HydrophobicContact CD1-CG 4.46Å; Y434-E436 HydrophobicContact CD1-CB 4.27Å; Y434-E436 HydrophobicContact CE1-CB 3.54Å; Y434-E436 WeakPolarHBondContact CE1-O 3.27Å; Y434-E436 HydrophobicContact CE2-CB 4.45Å; E436-T438 PolarHBondContact O-N 3.14Å; E436-A439 PolarHBondContact O-N 2.64Å; E436-A439 VanDerWaalsContact O-N 3.13Å; E436-L440 PolarHBondContact O-N 3.07Å
437T94.1Very high95.7Very high3 Ų316.9 Ų16.92%0.0189%0.089CC..Hα-helixtrans-59-30.4-17959.90000112.2G251 Q252 D408 A432 Y434 L435 L440 G441G251-T437 WeakPolarHBondContact CA-O 3.46Å; Q252-T437 HydrophobicContact CG-CG2 4.18Å; D408-T437 HydrophobicContact CB-CG2 3.75Å; D408-T437 PolarHBondContact OD1-OG1 2.67Å; D408-T437 PolarHBondContact OD2-OG1 3.03Å; A432-T437 HydrophobicContact CB-CG2 3.79Å; Y434-T437 VanDerWaalsContact O-CG2 3.24Å; Y434-T437 WeakPolarHBondContact O-CG2 3.29Å; L435-T437 PolarHBondContact O-N 3.1Å; L435-T437 VanDerWaalsContact O-N 3.11Å; T437-L440 PolarHBondContact O-N 2.56Å; T437-G441 PolarHBondContact O-N 2.72Å
438T95.8Very high95.8Very high14 Ų1417.5 Ų17.59%0.0869%0.092CC..Hα-helixtrans-53.5-54.5172.1-50.80000111.9T79 D244 A247 E436 G441 V442T79-T438 HydrophobicContact CG2-CG2 3.73Å; T79-T438 WeakPolarHBondContact OG1-CG2 3.06Å; D244-T438 HydrophobicContact CB-CG2 3.74Å; D244-T438 WeakPolarHBondContact O-CG2 3.28Å; A247-T438 HydrophobicContact CB-CG2 4.16Å; A247-T438 WeakPolarHBondContact CB-O 3.26Å; E436-T438 PolarHBondContact O-N 3.14Å; T438-G441 PolarHBondContact O-N 3.5Å; T438-V442 PolarHBondContact O-N 3.31Å
439A96.6Very high95.8Very high0 Ų018 Ų180%010%0.098CC..Hα-helixtrans-67.6-40.3-17900000111.4S7 D9 I18 F20 E436 G441 V442 A443S7-A439 VanDerWaalsContact CB-O 3.25Å; S7-A439 WeakPolarHBondContact CB-O 3.44Å; D9-A439 HydrophobicContact CB-CB 4.49Å; I18-A439 HydrophobicContact CD1-CB 3.64Å; I18-A439 HydrophobicContact CG1-CB 4.26Å; F20-A439 HydrophobicContact CE2-CB 4.45Å; F20-A439 HydrophobicContact CZ-CB 4.39Å; E436-A439 PolarHBondContact O-N 2.64Å; E436-A439 VanDerWaalsContact O-N 3.13Å; A439-G441 VanDerWaalsContact C-N 3.31Å; A439-G441 PolarHBondContact O-N 3.41Å; A439-V442 WeakPolarHBondContact O-CG2 3.47Å; A439-V442 PolarHBondContact O-N 3.24Å; A439-A443 PolarHBondContact O-N 3.36Å
440L95.8Very high95.8Very high13 Ų1320 Ų207%0.06811%0.11CC..Hα-helixtrans-61.2-39.2176.2-174.960.5000112.2F20 Y434 E436 T437 A443 Y444F20-L440 HydrophobicContact CD1-CD1 4.05Å; F20-L440 HydrophobicContact CE1-CD1 3.9Å; F20-L440 HydrophobicContact CZ-CB 4.32Å; F20-L440 HydrophobicContact CZ-CD1 4.28Å; Y434-L440 HydrophobicContact CD1-CB 4.29Å; Y434-L440 HydrophobicContact CD1-CD2 4.11Å; Y434-L440 HydrophobicContact CE1-CB 4.29Å; E436-L440 PolarHBondContact O-N 3.07Å; T437-L440 PolarHBondContact O-N 2.56Å; L440-A443 WeakPolarHBondContact O-CB 3.21Å; L440-A443 PolarHBondContact O-N 2.99Å; L440-Y444 HydrophobicContact CD1-CD1 4.5Å; L440-Y444 HydrophobicContact CD1-CE1 3.83Å; L440-Y444 HydrophobicContact CD1-CE2 4.07Å; L440-Y444 HydrophobicContact CD2-CE2 3.95Å; L440-Y444 HydrophobicContact CG-CD2 4.22Å; L440-Y444 HydrophobicContact CG-CE1 4.29Å; L440-Y444 HydrophobicContact CG-CE2 3.58Å; L440-Y444 PolarHBondContact O-N 3.4Å
441G97.5Very high95.8Very high0 Ų021.7 Ų21.70%013%0.133CC..Hα-helixtrans-61.9-47179.500000113.6A247 T437 T438 A439 A443 Y444 L445A247-G441 WeakPolarHBondContact O-CA 3.44Å; T437-G441 PolarHBondContact O-N 2.72Å; T438-G441 PolarHBondContact O-N 3.5Å; A439-G441 VanDerWaalsContact C-N 3.31Å; A439-G441 PolarHBondContact O-N 3.41Å; G441-A443 VanDerWaalsContact C-N 3.33Å; G441-Y444 WeakPolarHBondContact O-CB 3.49Å; G441-Y444 PolarHBondContact O-N 3.01Å; G441-L445 WeakPolarHBondContact O-CG 3.46Å; G441-L445 PolarHBondContact O-N 3.42Å
442V98.5Very high95.8Very high0 Ų020.5 Ų20.50%013%0.129CC..Hα-helixtrans-73.5-25175.1-73.40000113.4I78 T79 A242 A247 T438 A439 L445 A446I78-V442 WeakPolarHBondContact O-CG1 3.49Å; T79-V442 HydrophobicContact CG2-CG1 4.37Å; T79-V442 HydrophobicContact CG2-CG2 3.58Å; A242-V442 HydrophobicContact CB-CG1 4.07Å; A247-V442 HydrophobicContact CB-CG1 3.84Å; T438-V442 PolarHBondContact O-N 3.31Å; A439-V442 WeakPolarHBondContact O-CG2 3.47Å; A439-V442 PolarHBondContact O-N 3.24Å; V442-L445 HydrophobicContact CG1-CD1 4.17Å; V442-L445 PolarHBondContact O-N 3.04Å; V442-A446 WeakPolarHBondContact O-CB 3.17Å; V442-A446 PolarHBondContact O-N 3.2Å
443A98.3Very high95.9Very high0 Ų020.4 Ų20.40%013%0.126CC..Hα-helixtrans-60.6-50.4166.800000109.9I5 F20 A439 L440 G441 L445 A446 G447 W453I5-A443 HydrophobicContact CG2-CB 3.83Å; F20-A443 HydrophobicContact CD2-CB 3.51Å; F20-A443 HydrophobicContact CE2-CB 3.87Å; F20-A443 HydrophobicContact CG-CB 4.26Å; A439-A443 PolarHBondContact O-N 3.36Å; L440-A443 WeakPolarHBondContact O-CB 3.21Å; L440-A443 PolarHBondContact O-N 2.99Å; G441-A443 VanDerWaalsContact C-N 3.33Å; A443-L445 PolarHBondContact O-N 3.43Å; A443-A446 PolarHBondContact O-N 3.1Å; A443-G447 PolarHBondContact O-N 3.25Å; A443-W453 WeakPolarHBondContact O-CZ3 3.49Å
444Y97.8Very high96.1Very high8 Ų824.1 Ų24.13%0.03113%0.134CC..Hα-helixtrans-56.1-46.7175.1-66-32.7000112.7L253 L440 G441 A446 G447 L448 W453 I459 F462L253-Y444 HydrophobicContact CD2-CD2 4.11Å; L253-Y444 HydrophobicContact CD2-CE2 3.66Å; L440-Y444 HydrophobicContact CD1-CD1 4.5Å; L440-Y444 HydrophobicContact CD1-CE1 3.83Å; L440-Y444 HydrophobicContact CD1-CE2 4.07Å; L440-Y444 HydrophobicContact CD2-CE2 3.95Å; L440-Y444 HydrophobicContact CG-CD2 4.22Å; L440-Y444 HydrophobicContact CG-CE1 4.29Å; L440-Y444 HydrophobicContact CG-CE2 3.58Å; L440-Y444 PolarHBondContact O-N 3.4Å; G441-Y444 WeakPolarHBondContact O-CB 3.49Å; G441-Y444 PolarHBondContact O-N 3.01Å; Y444-A446 PolarHBondContact O-N 3.41Å; Y444-G447 PolarHBondContact O-N 2.88Å; Y444-L448 WeakPolarHBondContact O-CB 3.4Å; Y444-L448 VanDerWaalsContact O-CG 3.25Å; Y444-L448 WeakPolarHBondContact O-CG 3.46Å; Y444-L448 PolarHBondContact O-N 3.4Å; Y444-W453 HydrophobicContact CD1-CD2 4.44Å; Y444-W453 AromaticContact CD1-CE3 3.97Å; Y444-W453 HydrophobicContact CD1-CE3 3.97Å; Y444-W453 AromaticContact CD1-CH2 3.83Å; Y444-W453 HydrophobicContact CD1-CH2 3.83Å; Y444-W453 HydrophobicContact CD1-CZ2 4.29Å; Y444-W453 AromaticContact CD1-CZ3 3.67Å; Y444-W453 HydrophobicContact CD1-CZ3 3.67Å; Y444-W453 HydrophobicContact CE1-CH2 4.17Å; Y444-W453 HydrophobicContact CE1-CZ2 4.28Å; Y444-W453 HydrophobicContact CE1-CZ3 4.44Å; Y444-I459 HydrophobicContact CD1-CB 4.12Å; Y444-I459 HydrophobicContact CD1-CG2 3.75Å; Y444-I459 HydrophobicContact CD2-CD1 4.27Å; Y444-I459 HydrophobicContact CE1-CB 4.2Å; Y444-I459 HydrophobicContact CE1-CG2 4.16Å; Y444-I459 HydrophobicContact CG-CB 4.4Å; Y444-I459 HydrophobicContact CG-CD1 4.15Å; Y444-I459 HydrophobicContact CG-CG2 4.23Å; Y444-F462 HydrophobicContact CE1-CD2 4.18Å
445L98.6Very high96.4Very high0 Ų023.9 Ų23.90%014%0.136CC..Hα-helixtrans-59-46.9177.4-67.7170.4000112.3N219 S220 A242 V250 I293 G441 V442 A443 A449N219-L445 HydrophobicContact CB-CD1 4.15Å; N219-L445 HydrophobicContact CB-CD2 4.17Å; S220-L445 PolarHBondContact OG-O 3.44Å; A242-L445 HydrophobicContact CB-CD1 3.81Å; V250-L445 HydrophobicContact CG1-CD2 4.3Å; V250-L445 HydrophobicContact CG1-CG 4.2Å; V250-L445 HydrophobicContact CG2-CD2 4.48Å; I293-L445 HydrophobicContact CD1-CD2 3.57Å; I293-L445 HydrophobicContact CG1-CD2 3.96Å; G441-L445 WeakPolarHBondContact O-CG 3.46Å; G441-L445 PolarHBondContact O-N 3.42Å; V442-L445 HydrophobicContact CG1-CD1 4.17Å; V442-L445 PolarHBondContact O-N 3.04Å; A443-L445 PolarHBondContact O-N 3.43Å; L445-A449 PolarHBondContact O-N 3.03Å
446A98.7Very high96.8Very high0 Ų024.8 Ų24.80%014%0.141CC..Hα-helixtrans-65.7-41.8177.500000112.1I5 A239 V442 A443 Y444 A449 V450I5-A446 HydrophobicContact CG2-CB 4.2Å; A239-A446 HydrophobicContact CB-CB 4.23Å; V442-A446 WeakPolarHBondContact O-CB 3.17Å; V442-A446 PolarHBondContact O-N 3.2Å; A443-A446 PolarHBondContact O-N 3.1Å; Y444-A446 PolarHBondContact O-N 3.41Å; A446-A449 PolarHBondContact O-N 3.48Å; A446-V450 WeakPolarHBondContact O-CG2 3.44Å; A446-V450 PolarHBondContact O-N 3.35Å; A446-V450 VanDerWaalsContact O-N 3.11Å
447G98.3Very high97Very high0 Ų027.6 Ų27.60%016%0.157CC..Hα-helixtrans-66.7-36.5-179.800000113.3A443 Y444 G451 Y452 W453A443-G447 PolarHBondContact O-N 3.25Å; Y444-G447 PolarHBondContact O-N 2.88Å; G447-G451 CarbonylContact O-C 3.56Å; G447-G451 PolarHBondContact O-N 3.13Å; G447-G451 VanDerWaalsContact O-N 3.13Å; G447-Y452 WeakPolarHBondContact O-CA 3.39Å; G447-Y452 WeakPolarHBondContact O-CB 3.38Å; G447-Y452 PolarHBondContact O-N 3.3Å; G447-W453 PolarHBondContact O-N 2.97Å
448L98Very high97Very high28 Ų2829.2 Ų29.215%0.14717%0.166CC..Hα-helixtrans-63.7-46.4171.9-72170.1000111Y444 V450 G451 W453 D455 I456 I459Y444-L448 WeakPolarHBondContact O-CB 3.4Å; Y444-L448 VanDerWaalsContact O-CG 3.25Å; Y444-L448 WeakPolarHBondContact O-CG 3.46Å; Y444-L448 PolarHBondContact O-N 3.4Å; L448-V450 VanDerWaalsContact C-N 3.33Å; L448-V450 PolarHBondContact O-N 3.44Å; L448-G451 PolarHBondContact O-N 2.95Å; L448-W453 HydrophobicContact CD2-CB 4.34Å; L448-D455 VanDerWaalsContact CD2-C 3.48Å; L448-I456 HydrophobicContact CD1-CG1 4.3Å; L448-I459 HydrophobicContact CD1-CD1 4.31Å
449A98.4Very high96.9Very high32 Ų3228.6 Ų28.626%0.26416%0.162SC..Hα-helixtrans-63.9-33.5-177.800000113.9S220 A239 L445 A446S220-A449 PolarHBondContact OG-N 3.42Å; A239-A449 HydrophobicContact CB-CB 3.83Å; A239-A449 WeakPolarHBondContact O-CB 3.3Å; L445-A449 PolarHBondContact O-N 3.03Å; A446-A449 PolarHBondContact O-N 3.48Å
450V98.2Very high96.7Very high42 Ų4231.7 Ų31.726%0.25518%0.175SC..THydrogen-bonded Turntrans-95.40.6177.7-53.70000113.7I5 V222 P237 A239 A446 L448 Y452I5-V450 HydrophobicContact CD1-CG2 4.02Å; V222-V450 HydrophobicContact CG2-CG1 4.4Å; P237-V450 HydrophobicContact CB-CG1 4.26Å; P237-V450 HydrophobicContact CG-CG1 3.88Å; A239-V450 HydrophobicContact CB-CG1 3.57Å; A446-V450 WeakPolarHBondContact O-CG2 3.44Å; A446-V450 PolarHBondContact O-N 3.35Å; A446-V450 VanDerWaalsContact O-N 3.11Å; L448-V450 VanDerWaalsContact C-N 3.33Å; L448-V450 PolarHBondContact O-N 3.44Å; V450-Y452 VanDerWaalsContact C-N 3.33Å
451G97.2Very high96.4Very high57 Ų5738 Ų3859%0.58820%0.202SC*.THydrogen-bonded Turntrans72.421.3-178.400000114.8G447 L448 W453G447-G451 CarbonylContact O-C 3.56Å; G447-G451 PolarHBondContact O-N 3.13Å; G447-G451 VanDerWaalsContact O-N 3.13Å; L448-G451 PolarHBondContact O-N 2.95Å; G451-W453 VanDerWaalsContact C-N 3.32Å
452Y97.1Very high95.7Very high11 Ų1141 Ų414%0.04322%0.215CC..SBendtrans-64.2-40.3170.6-168.9-105.1000111.2S3 I5 D21 K22 E74 G447 V450S3-Y452 WeakPolarHBondContact O-CE2 3.47Å; S3-Y452 PolarHBondContact O-OH 3.13Å; I5-Y452 HydrophobicContact CD1-CD1 4.31Å; I5-Y452 HydrophobicContact CD1-CD2 4.25Å; I5-Y452 HydrophobicContact CD1-CG 3.96Å; I5-Y452 HydrophobicContact CG1-CD1 3.55Å; I5-Y452 HydrophobicContact CG1-CD2 4.17Å; I5-Y452 HydrophobicContact CG1-CE1 3.85Å; I5-Y452 HydrophobicContact CG1-CE2 4.43Å; I5-Y452 HydrophobicContact CG1-CG 3.71Å; D21-Y452 WeakPolarHBondContact CA-OH 3.47Å; K22-Y452 HydrophobicContact CB-CE1 4.28Å; K22-Y452 HydrophobicContact CD-CE2 4.38Å; K22-Y452 HydrophobicContact CG-CE1 3.73Å; K22-Y452 HydrophobicContact CG-CE2 3.74Å; K22-Y452 WeakPolarHBondContact CG-OH 3.47Å; K22-Y452 PolarHBondContact N-OH 3.04Å; E74-Y452 HydrophobicContact CB-CD2 4.35Å; E74-Y452 VanDerWaalsContact OE2-CD2 3.32Å; E74-Y452 WeakPolarHBondContact OE2-CD2 3.35Å; G447-Y452 WeakPolarHBondContact O-CA 3.39Å; G447-Y452 WeakPolarHBondContact O-CB 3.38Å; G447-Y452 PolarHBondContact O-N 3.3Å; V450-Y452 VanDerWaalsContact C-N 3.33Å
453W97Very high94.9Very high5 Ų544 Ų442%0.01924%0.241CC..SBendtrans-115.3146.9164.1-63.1-65.2000109.6I5 K22 A443 Y444 G447 L448 G451 I459 F462I5-W453 HydrophobicContact CG1-CH2 4.41Å; I5-W453 HydrophobicContact CG1-CZ3 4.3Å; K22-W453 PolarHBondContact O-NE1 2.74Å; A443-W453 WeakPolarHBondContact O-CZ3 3.49Å; Y444-W453 HydrophobicContact CD1-CD2 4.44Å; Y444-W453 AromaticContact CD1-CE3 3.97Å; Y444-W453 HydrophobicContact CD1-CE3 3.97Å; Y444-W453 AromaticContact CD1-CH2 3.83Å; Y444-W453 HydrophobicContact CD1-CH2 3.83Å; Y444-W453 HydrophobicContact CD1-CZ2 4.29Å; Y444-W453 AromaticContact CD1-CZ3 3.67Å; Y444-W453 HydrophobicContact CD1-CZ3 3.67Å; Y444-W453 HydrophobicContact CE1-CH2 4.17Å; Y444-W453 HydrophobicContact CE1-CZ2 4.28Å; Y444-W453 HydrophobicContact CE1-CZ3 4.44Å; G447-W453 PolarHBondContact O-N 2.97Å; L448-W453 HydrophobicContact CD2-CB 4.34Å; G451-W453 VanDerWaalsContact C-N 3.32Å; W453-I459 HydrophobicContact CB-CG2 3.78Å; W453-I459 HydrophobicContact CD2-CG2 3.84Å; W453-I459 HydrophobicContact CE3-CG2 4.11Å; W453-I459 HydrophobicContact CG-CG2 3.7Å; W453-F462 AromaticContact CD1-CE2 3.65Å; W453-F462 AromaticContact CD1-CZ 3.88Å; W453-F462 AromaticContact CE2-CE2 3.88Å; W453-F462 HydrophobicContact CG-CE2 4.46Å; W453-F462 HydrophobicContact CZ2-CE2 4.47Å; W453-F462 AromaticContact NE1-CE2 3.23Å; W453-F462 AromaticContact NE1-CZ 3.51Å
454K95.4Very high94.1Very high166 Ų16647.5 Ų47.572%0.72227%0.265SS*.  trans-73.8-44.1-170.8-178.9178.9166.4-96.80113.5D458K454-D458 HydrophobicContact CB-CB 4.31Å; K454-D458 PolarHBondContact N-OD2 3.09Å
455D95.7Very high93.4Very high47 Ų4754.2 Ų54.225%0.25130%0.301SS..SBendtrans-165.3174.9-171.548.744.2000110.2L448 D457 D458 I459L448-D455 VanDerWaalsContact CD2-C 3.48Å; D455-D457 PolarHBondContact O-N 3.41Å; D455-D457 WeakPolarHBondContact OD1-CB 3.22Å; D455-D457 PolarHBondContact OD1-N 3.2Å; D455-D458 VanDerWaalsContact O-CB 3.32Å; D455-D458 WeakPolarHBondContact O-CB 3.31Å; D455-D458 PolarHBondContact O-N 3.39Å; D455-D458 VanDerWaalsContact O-N 3.08Å; D455-D458 PolarHBondContact OD1-N 3.45Å; D455-I459 PolarHBondContact O-N 3.47Å
456I95.3Very high93Very high42 Ų4255 Ų5522%0.21531%0.31CS..Hα-helixtrans-59.7-33.5178.2-67.8173.4000111.6F255 L448 D458 I459 K460F255-I456 HydrophobicContact CB-CG2 4.43Å; F255-I456 HydrophobicContact CD1-CD1 3.96Å; F255-I456 HydrophobicContact CD1-CG2 4.25Å; F255-I456 HydrophobicContact CD2-CG2 3.54Å; F255-I456 HydrophobicContact CE1-CD1 4.05Å; F255-I456 HydrophobicContact CE1-CG1 4.34Å; F255-I456 HydrophobicContact CE1-CG2 4.42Å; F255-I456 HydrophobicContact CE2-CG2 3.72Å; F255-I456 HydrophobicContact CG-CD1 4.48Å; F255-I456 HydrophobicContact CG-CG2 3.81Å; F255-I456 HydrophobicContact CZ-CG1 4.44Å; F255-I456 HydrophobicContact CZ-CG2 4.17Å; L448-I456 HydrophobicContact CD1-CG1 4.3Å; I456-D458 VanDerWaalsContact C-N 3.26Å; I456-D458 PolarHBondContact O-N 3.43Å; I456-I459 WeakPolarHBondContact O-CG1 3.3Å; I456-I459 PolarHBondContact O-N 3.37Å; I456-K460 HydrophobicContact CG2-CD 4.18Å; I456-K460 HydrophobicContact CG2-CG 4.28Å; I456-K460 WeakPolarHBondContact O-CB 3.41Å; I456-K460 WeakPolarHBondContact O-CG 3.35Å; I456-K460 PolarHBondContact O-N 3.01Å
457D95Very high92.8Very high111 Ų11159.7 Ų59.759%0.59433%0.332SS*.Hα-helixtrans-67.4-30.4177.7-71.5-27.3000111.7D455 K461D455-D457 PolarHBondContact O-N 3.41Å; D455-D457 WeakPolarHBondContact OD1-CB 3.22Å; D455-D457 PolarHBondContact OD1-N 3.2Å; D457-K461 WeakPolarHBondContact O-CG 3.47Å
458D94Very high92.8Very high38 Ų3866 Ų6620%0.20336%0.356CS..Hα-helixtrans-66.7-46.3175.1-15331.5000112.1K454 D455 I456 K461K454-D458 HydrophobicContact CB-CB 4.31Å; K454-D458 PolarHBondContact N-OD2 3.09Å; D455-D458 VanDerWaalsContact O-CB 3.32Å; D455-D458 WeakPolarHBondContact O-CB 3.31Å; D455-D458 PolarHBondContact O-N 3.39Å; D455-D458 VanDerWaalsContact O-N 3.08Å; D455-D458 PolarHBondContact OD1-N 3.45Å; I456-D458 VanDerWaalsContact C-N 3.26Å; I456-D458 PolarHBondContact O-N 3.43Å; D458-K461 WeakPolarHBondContact O-CB 3.39Å; D458-K461 PolarHBondContact O-N 3.06Å; D458-K461 IonicContact OD1-NZ 2.73Å; D458-K461 PolarHBondContact OD1-NZ 2.64Å
459I93.5Very high92.8Very high0 Ų065.2 Ų65.20%035%0.351CS..Hα-helixtrans-69.5-32.2176.961.9174.8000112.3L253 F255 Y444 L448 W453 D455 I456 K461 F462L253-I459 HydrophobicContact CD2-CD1 4.15Å; L253-I459 HydrophobicContact CD2-CG1 4.2Å; F255-I459 HydrophobicContact CE2-CD1 3.69Å; F255-I459 HydrophobicContact CE2-CG1 4.44Å; F255-I459 HydrophobicContact CZ-CD1 3.58Å; Y444-I459 HydrophobicContact CD1-CB 4.12Å; Y444-I459 HydrophobicContact CD1-CG2 3.75Å; Y444-I459 HydrophobicContact CD2-CD1 4.27Å; Y444-I459 HydrophobicContact CE1-CB 4.2Å; Y444-I459 HydrophobicContact CE1-CG2 4.16Å; Y444-I459 HydrophobicContact CG-CB 4.4Å; Y444-I459 HydrophobicContact CG-CD1 4.15Å; Y444-I459 HydrophobicContact CG-CG2 4.23Å; L448-I459 HydrophobicContact CD1-CD1 4.31Å; W453-I459 HydrophobicContact CB-CG2 3.78Å; W453-I459 HydrophobicContact CD2-CG2 3.84Å; W453-I459 HydrophobicContact CE3-CG2 4.11Å; W453-I459 HydrophobicContact CG-CG2 3.7Å; D455-I459 PolarHBondContact O-N 3.47Å; I456-I459 WeakPolarHBondContact O-CG1 3.3Å; I456-I459 PolarHBondContact O-N 3.37Å; I459-K461 PolarHBondContact O-N 2.99Å; I459-K461 VanDerWaalsContact O-N 3.13Å; I459-F462 HydrophobicContact CB-CD2 4.44Å; I459-F462 WeakPolarHBondContact O-CB 3.17Å; I459-F462 WeakPolarHBondContact O-CD2 3.43Å; I459-F462 PolarHBondContact O-N 3.07Å
460K92.5Very high92.8Very high65 Ų6568 Ų6828%0.28336%0.358SS..Hα-helixtrans-61-21.2176-81-177.4174.7-171.20112.6D256 I456 F462 A463D256-K460 IonicContact OD1-NZ 3.11Å; D256-K460 IonicContact OD2-NZ 2.72Å; D256-K460 PolarHBondContact OD2-NZ 2.92Å; D256-K460 VanDerWaalsContact OD2-NZ 3.11Å; I456-K460 HydrophobicContact CG2-CD 4.18Å; I456-K460 HydrophobicContact CG2-CG 4.28Å; I456-K460 WeakPolarHBondContact O-CB 3.41Å; I456-K460 WeakPolarHBondContact O-CG 3.35Å; I456-K460 PolarHBondContact O-N 3.01Å; K460-F462 PolarHBondContact O-N 3.22Å; K460-A463 WeakPolarHBondContact O-CB 3.48Å; K460-A463 PolarHBondContact O-N 2.84Å; K460-A463 VanDerWaalsContact O-N 3.15Å
461K89.6Confident92.8Very high146 Ų14667.9 Ų67.964%0.63536%0.359SS*.THydrogen-bonded Turntrans-68.6-18.1174.7-62.7166.2-163.7160.70113.5D457 D458 I459 A463D457-K461 WeakPolarHBondContact O-CG 3.47Å; D458-K461 WeakPolarHBondContact O-CB 3.39Å; D458-K461 PolarHBondContact O-N 3.06Å; D458-K461 IonicContact OD1-NZ 2.73Å; D458-K461 PolarHBondContact OD1-NZ 2.64Å; I459-K461 PolarHBondContact O-N 2.99Å; I459-K461 VanDerWaalsContact O-N 3.13Å; K461-A463 VanDerWaalsContact C-N 3.3Å
462F83.3Confident92.8Very high62 Ų6269.1 Ų69.127%0.27236%0.363SS..THydrogen-bonded Turntrans-85.7-5.2174.8-49.8-45.8000112.8K22 Y444 W453 I459 K460 S464K22-F462 WeakPolarHBondContact O-CZ 3.27Å; Y444-F462 HydrophobicContact CE1-CD2 4.18Å; W453-F462 AromaticContact CD1-CE2 3.65Å; W453-F462 AromaticContact CD1-CZ 3.88Å; W453-F462 AromaticContact CE2-CE2 3.88Å; W453-F462 HydrophobicContact CG-CE2 4.46Å; W453-F462 HydrophobicContact CZ2-CE2 4.47Å; W453-F462 AromaticContact NE1-CE2 3.23Å; W453-F462 AromaticContact NE1-CZ 3.51Å; I459-F462 HydrophobicContact CB-CD2 4.44Å; I459-F462 WeakPolarHBondContact O-CB 3.17Å; I459-F462 WeakPolarHBondContact O-CD2 3.43Å; I459-F462 PolarHBondContact O-N 3.07Å; K460-F462 PolarHBondContact O-N 3.22Å; F462-S464 PolarHBondContact O-N 3.26Å; F462-S464 VanDerWaalsContact O-N 3.17Å
463A81.3Confident92.8Very high65 Ų6570.8 Ų70.854%0.53737%0.372SS..  trans-56.7123173.900000109.6L253 K460 K461L253-A463 HydrophobicContact CD1-CB 3.64Å; K460-A463 WeakPolarHBondContact O-CB 3.48Å; K460-A463 PolarHBondContact O-N 2.84Å; K460-A463 VanDerWaalsContact O-N 3.15Å; K461-A463 VanDerWaalsContact C-N 3.3Å
464S80.5Confident92.8Very high73 Ų7376.5 Ų76.551%0.5140%0.403SS..  trans-125.5137.9169.561.10000108.8P433 F462 G466P433-S464 VanDerWaalsContact CG-OG 3.26Å; P433-S464 WeakPolarHBondContact CG-OG 3.21Å; F462-S464 PolarHBondContact O-N 3.26Å; F462-S464 VanDerWaalsContact O-N 3.17Å; S464-G466 PolarHBondContact O-N 2.85Å
465D83Confident92.9Very high148 Ų14872.8 Ų72.879%0.79139%0.388SS*.  trans-61.7133.2-179.8-62.7-24.3000110.5
466G90.2Very high93Very high18 Ų1877 Ų7719%0.18641%0.411CS..  trans-79.5178.5176.600000113.2R431 S464 R468R431-G466 WeakPolarHBondContact O-CA 3.47Å; S464-G466 PolarHBondContact O-N 2.85Å; G466-R468 PolarHBondContact O-N 3.28Å
467Q95.4Very high93.1Very high98 Ų9878.3 Ų78.346%0.45842%0.42SS..EExtended strand (participates in β ladder)trans-71125.6165.2-177171.7-6.300109.1R431 Y469R431-Q467 PolarHBondContact N-O 3.3Å; R431-Q467 PolarHBondContact O-N 3.18Å; Q467-Y469 HydrophobicContact CB-CE2 4.31Å; Q467-Y469 VanDerWaalsContact CD-OH 3.28Å; Q467-Y469 HydrophobicContact CG-CE2 3.91Å; Q467-Y469 PolarHBondContact NE2-OH 2.93Å; Q467-Y469 PolarHBondContact OE1-OH 3.38Å
468R97.1Very high93.2Very high131 Ų13173.1 Ų73.149%0.49439%0.393SS..EExtended strand (participates in β ladder)trans-107136.6-177.1-174.9167.4165.1169.9-5111.4V429 G466 E470V429-R468 CarbonylContact O-C 3.59Å; V429-R468 WeakPolarHBondContact O-CA 3.44Å; G466-R468 PolarHBondContact O-N 3.28Å; R468-E470 IonicContact CZ-OE1 3.85Å; R468-E470 IonicContact NE-OE1 3.72Å; R468-E470 PolarHBondContact NE-OE1 3.05Å; R468-E470 IonicContact NH2-OE1 2.6Å; R468-E470 PolarHBondContact NH2-OE1 2.81Å; R468-E470 IonicContact NH2-OE2 3.35Å
469Y98.3Very high93.4Very high12 Ų1275 Ų755%0.04740%0.403CS..EExtended strand (participates in β ladder)trans-116.2122.5179-55.6-100.3000107.8D415 L418 Q419 P428 V429 R431 Q467D415-Y469 HydrophobicContact CB-CE1 4.18Å; D415-Y469 PolarHBondContact OD1-OH 3.07Å; L418-Y469 HydrophobicContact CB-CD1 4.16Å; L418-Y469 HydrophobicContact CB-CD2 3.88Å; L418-Y469 HydrophobicContact CB-CE1 4.04Å; L418-Y469 HydrophobicContact CB-CE2 3.8Å; L418-Y469 HydrophobicContact CB-CG 4.08Å; L418-Y469 HydrophobicContact CD1-CD2 4.15Å; L418-Y469 HydrophobicContact CD1-CE2 3.5Å; L418-Y469 VanDerWaalsContact CD1-CE2 3.5Å; L418-Y469 HydrophobicContact CG-CE2 4.32Å; Q419-Y469 HydrophobicContact CB-CD1 4.27Å; P428-Y469 WeakPolarHBondContact CA-O 3.42Å; V429-Y469 PolarHBondContact N-O 3.02Å; V429-Y469 PolarHBondContact O-N 3.43Å; R431-Y469 HydrophobicContact CB-CE2 4.26Å; R431-Y469 PolarHBondContact NH1-OH 2.87Å; R431-Y469 PolarHBondContact NH2-OH 3.38Å; R431-Y469 VanDerWaalsContact NH2-OH 3.09Å; Q467-Y469 HydrophobicContact CB-CE2 4.31Å; Q467-Y469 VanDerWaalsContact CD-OH 3.28Å; Q467-Y469 HydrophobicContact CG-CE2 3.91Å; Q467-Y469 PolarHBondContact NE2-OH 2.93Å; Q467-Y469 PolarHBondContact OE1-OH 3.38Å
470E98.3Very high93.6Very high91 Ų9180 Ų8043%0.42543%0.43SS..  trans-97.4144.1177.9-66.2-64.2161.800109.5Q419 P428 R468 A472Q419-E470 PolarHBondContact NE2-O 3.13Å; P428-E470 WeakPolarHBondContact CG-OE2 3.32Å; R468-E470 IonicContact CZ-OE1 3.85Å; R468-E470 IonicContact NE-OE1 3.72Å; R468-E470 PolarHBondContact NE-OE1 3.05Å; R468-E470 IonicContact NH2-OE1 2.6Å; R468-E470 PolarHBondContact NH2-OE1 2.81Å; R468-E470 IonicContact NH2-OE2 3.35Å; E470-A472 PolarHBondContact O-N 3.02Å
471P98.2Very high93.9Very high40 Ų4078.1 Ų78.126%0.2642%0.423SS..  trans-55.5129.7171.8-21.231.6000111Q426Q426-P471 VanDerWaalsContact C-CG 3.49Å
472A97.6Very high94.3Very high83 Ų8373 Ų7369%0.68640%0.4SS*.  trans-126.9-8.1-178.300000113.1D423 E470D423-A472 PolarHBondContact OD1-N 3.41Å; E470-A472 PolarHBondContact O-N 3.02Å
473M97.3Very high95Very high45 Ų4572.2 Ų72.222%0.22240%0.404CS..SBendtrans-93.2137.4176-167.6177.7-62.500111.5F420 D423 Q426 V477 T478 L481F420-M473 HydrophobicContact CD2-CE 4.15Å; F420-M473 HydrophobicContact CE2-CE 4.08Å; D423-M473 HydrophobicContact CB-CB 3.72Å; D423-M473 HydrophobicContact CB-CE 4.33Å; D423-M473 PolarHBondContact OD1-N 2.9Å; Q426-M473 PolarHBondContact NE2-O 3.09Å; M473-V477 HydrophobicContact CG-CB 4.02Å; M473-V477 HydrophobicContact CG-CG1 3.98Å; M473-V477 HydrophobicContact SD-CB 4.23Å; M473-V477 HydrophobicContact SD-CG1 3.68Å; M473-T478 HydrophobicContact CB-CG2 3.83Å; M473-T478 HydrophobicContact CG-CG2 3.69Å; M473-T478 HydrophobicContact SD-CG2 3.57Å; M473-T478 VanDerWaalsContact SD-CG2 3.57Å; M473-L481 HydrophobicContact CE-CD1 4.25Å; M473-L481 HydrophobicContact SD-CD1 3.61Å
474D97.6Very high95.8Very high125 Ų12569.9 Ų69.967%0.66839%0.387SS*.  trans-61.5141.2177.2-70.9-37.1000112.1D476 V477 T478D474-D476 VanDerWaalsContact C-N 3.32Å; D474-D476 PolarHBondContact O-N 3.37Å; D474-V477 HydrophobicContact CB-CG2 4.27Å; D474-V477 WeakPolarHBondContact O-CB 3.33Å; D474-V477 PolarHBondContact O-N 3.44Å; D474-T478 PolarHBondContact O-N 2.95Å; D474-T478 VanDerWaalsContact O-N 3.1Å
475Q96.4Very high96.7Very high88 Ų8866.5 Ų66.541%0.41136%0.363SS..Hα-helixtrans-52.5-46.7-177.9-175.569.261.400112.5V477 T478 D479Q475-V477 PolarHBondContact O-N 2.97Å; Q475-T478 WeakPolarHBondContact CA-OG1 3.26Å; Q475-T478 PolarHBondContact NE2-OG1 2.8Å; Q475-T478 PolarHBondContact O-N 2.92Å; Q475-T478 PolarHBondContact O-OG1 3.27Å; Q475-D479 PolarHBondContact NE2-OD1 2.95Å; Q475-D479 PolarHBondContact O-N 2.96Å
476D97.8Very high97.4Very high136 Ų13662 Ų6273%0.72734%0.337SS*.Hα-helixtrans-59-36.4-178.7-70.2-10.3000112.1D474 D480D474-D476 VanDerWaalsContact C-N 3.32Å; D474-D476 PolarHBondContact O-N 3.37Å; D476-D480 PolarHBondContact O-N 3.2Å
477V97.4Very high97.8Very high69 Ų6968.1 Ų68.142%0.41836%0.361SS..Hα-helixtrans-71.3-43.1176.8-178.80000110.1M473 D474 Q475 D479 D480 L481M473-V477 HydrophobicContact CG-CB 4.02Å; M473-V477 HydrophobicContact CG-CG1 3.98Å; M473-V477 HydrophobicContact SD-CB 4.23Å; M473-V477 HydrophobicContact SD-CG1 3.68Å; D474-V477 HydrophobicContact CB-CG2 4.27Å; D474-V477 WeakPolarHBondContact O-CB 3.33Å; D474-V477 PolarHBondContact O-N 3.44Å; Q475-V477 PolarHBondContact O-N 2.97Å; V477-D479 VanDerWaalsContact C-N 3.31Å; V477-D479 PolarHBondContact O-N 3.22Å; V477-D480 PolarHBondContact O-N 3.16Å; V477-L481 HydrophobicContact CG1-CD1 4.12Å; V477-L481 HydrophobicContact CG1-CG 4.43Å; V477-L481 WeakPolarHBondContact O-CB 3.46Å; V477-L481 VanDerWaalsContact O-CG 3.29Å; V477-L481 WeakPolarHBondContact O-CG 3.32Å; V477-L481 PolarHBondContact O-N 3.3Å
478T97.5Very high98Very high2 Ų263.7 Ų63.71%0.01234%0.341CS..Hα-helixtrans-65.6-34.7178.461.50000112.7D423 M473 D474 Q475 Y482D423-T478 WeakPolarHBondContact O-CG2 3.29Å; M473-T478 HydrophobicContact CB-CG2 3.83Å; M473-T478 HydrophobicContact CG-CG2 3.69Å; M473-T478 HydrophobicContact SD-CG2 3.57Å; M473-T478 VanDerWaalsContact SD-CG2 3.57Å; D474-T478 PolarHBondContact O-N 2.95Å; D474-T478 VanDerWaalsContact O-N 3.1Å; Q475-T478 WeakPolarHBondContact CA-OG1 3.26Å; Q475-T478 PolarHBondContact NE2-OG1 2.8Å; Q475-T478 PolarHBondContact O-N 2.92Å; Q475-T478 PolarHBondContact O-OG1 3.27Å; T478-Y482 WeakPolarHBondContact O-CB 3.22Å; T478-Y482 PolarHBondContact O-N 3.33Å
479D97.8Very high98Very high78 Ų7857.5 Ų57.542%0.41732%0.318SS..Hα-helixtrans-68.5-41.7177.4-73.9-12.3000111.3Q475 V477 Y482 A483Q475-D479 PolarHBondContact NE2-OD1 2.95Å; Q475-D479 PolarHBondContact O-N 2.96Å; V477-D479 VanDerWaalsContact C-N 3.31Å; V477-D479 PolarHBondContact O-N 3.22Å; D479-Y482 PolarHBondContact O-N 3.33Å; D479-A483 WeakPolarHBondContact O-CB 3.33Å; D479-A483 PolarHBondContact O-N 3.27Å
480D98.1Very high98Very high106 Ų10661.4 Ų61.457%0.56734%0.337SS*.Hα-helixtrans-63.5-48175.2-173.361.3000111.8D476 V477 Y482 A483 G484D476-D480 PolarHBondContact O-N 3.2Å; V477-D480 PolarHBondContact O-N 3.16Å; D480-Y482 VanDerWaalsContact C-N 3.34Å; D480-Y482 PolarHBondContact O-N 3.25Å; D480-A483 PolarHBondContact O-N 2.93Å; D480-G484 PolarHBondContact O-N 2.9Å
481L98.4Very high98Very high25 Ų2559.2 Ų59.213%0.13133%0.334CS..Hα-helixtrans-59.4-44.1175.5-74.4177.7000112.1Y342 Y385 F420 I424 M473 V477 G484 W485Y342-L481 PolarHBondContact OH-O 3.04Å; Y342-L481 VanDerWaalsContact OH-O 3.06Å; Y385-L481 HydrophobicContact CE1-CB 4.33Å; Y385-L481 WeakPolarHBondContact OH-CB 3.13Å; F420-L481 HydrophobicContact CE2-CD1 4.16Å; F420-L481 HydrophobicContact CZ-CD1 4.44Å; I424-L481 HydrophobicContact CD1-CB 4.49Å; M473-L481 HydrophobicContact CE-CD1 4.25Å; M473-L481 HydrophobicContact SD-CD1 3.61Å; V477-L481 HydrophobicContact CG1-CD1 4.12Å; V477-L481 HydrophobicContact CG1-CG 4.43Å; V477-L481 WeakPolarHBondContact O-CB 3.46Å; V477-L481 VanDerWaalsContact O-CG 3.29Å; V477-L481 WeakPolarHBondContact O-CG 3.32Å; V477-L481 PolarHBondContact O-N 3.3Å; L481-G484 PolarHBondContact O-N 3.37Å; L481-W485 PolarHBondContact O-N 3.19Å; L481-W485 VanDerWaalsContact O-N 3.09Å
482Y98.4Very high98Very high38 Ų3857.4 Ų57.415%0.14932%0.322CS..Hα-helixtrans-68.2-36.8178.6-169.3-115.2000112.1Y385 A388 D389 K392 I424 T478 D479 D480 W485 Q486Y385-Y482 HydrophobicContact CD1-CD2 4.18Å; A388-Y482 HydrophobicContact CB-CE2 4.08Å; D389-Y482 WeakPolarHBondContact OD1-CE2 3.33Å; D389-Y482 VanDerWaalsContact OD1-CZ 3.22Å; D389-Y482 PolarHBondContact OD1-OH 3.19Å; K392-Y482 HydrophobicContact CD-CE1 3.85Å; K392-Y482 HydrophobicContact CD-CE2 4.47Å; I424-Y482 HydrophobicContact CG1-CD2 4.47Å; T478-Y482 WeakPolarHBondContact O-CB 3.22Å; T478-Y482 PolarHBondContact O-N 3.33Å; D479-Y482 PolarHBondContact O-N 3.33Å; D480-Y482 VanDerWaalsContact C-N 3.34Å; D480-Y482 PolarHBondContact O-N 3.25Å; Y482-W485 AromaticContact CE2-CD1 3.86Å; Y482-W485 PolarHBondContact O-N 2.98Å; Y482-W485 WeakPolarHBondContact O-CB 3.24Å; Y482-Q486 HydrophobicContact CD1-CG 4.29Å; Y482-Q486 HydrophobicContact CE1-CG 4.01Å; Y482-Q486 WeakPolarHBondContact O-CG 3.29Å; Y482-Q486 PolarHBondContact O-N 3.34Å; Y482-Q486 PolarHBondContact OH-NE2 3Å; Y482-Q486 VanDerWaalsContact OH-NE2 3.16Å
483A98.4Very high98Very high45 Ų4554.9 Ų54.937%0.37230%0.296SS..Hα-helixtrans-61.6-44.8174.800000111.5D479 D480 W485 Q486 E487D479-A483 WeakPolarHBondContact O-CB 3.33Å; D479-A483 PolarHBondContact O-N 3.27Å; D480-A483 PolarHBondContact O-N 2.93Å; A483-W485 VanDerWaalsContact C-N 3.33Å; A483-W485 PolarHBondContact O-N 3.19Å; A483-Q486 PolarHBondContact O-N 3.28Å; A483-E487 PolarHBondContact O-N 3.1Å
484G98.6Very high98Very high17 Ų1759.9 Ų59.918%0.17532%0.319CS..Hα-helixtrans-61.1-39.3174.700000113.2D480 L481 E487 A488D480-G484 PolarHBondContact O-N 2.9Å; L481-G484 PolarHBondContact O-N 3.37Å; G484-E487 PolarHBondContact O-N 3.4Å; G484-A488 PolarHBondContact O-N 3.01Å
485W98.6Very high97.9Very high1 Ų160.8 Ų60.80%0.00431%0.314CS..Hα-helixtrans-60.7-47.3172.3163.9-103.6000112.2Y342 V344 Y385 Q386 D389 L481 Y482 A483 E487 A488 V489Y342-W485 HydrophobicContact CD1-CB 4.1Å; Y342-W485 HydrophobicContact CD1-CE3 4.41Å; Y342-W485 HydrophobicContact CE1-CB 3.92Å; Y342-W485 VanDerWaalsContact CE1-N 3.3Å; V344-W485 HydrophobicContact CB-CZ3 4.46Å; V344-W485 HydrophobicContact CG1-CH2 4.3Å; V344-W485 HydrophobicContact CG2-CE3 4.47Å; V344-W485 HydrophobicContact CG2-CH2 4.31Å; V344-W485 HydrophobicContact CG2-CZ3 3.86Å; Y385-W485 VanDerWaalsContact CB-CE2 3.44Å; Y385-W485 HydrophobicContact CD1-CB 3.83Å; Y385-W485 AromaticContact CD1-CG 3.96Å; Y385-W485 HydrophobicContact CD1-CG 3.96Å; Y385-W485 HydrophobicContact CD2-CB 4.07Å; Y385-W485 AromaticContact CD2-CD2 3.94Å; Y385-W485 HydrophobicContact CD2-CD2 3.94Å; Y385-W485 AromaticContact CD2-CE3 3.73Å; Y385-W485 HydrophobicContact CD2-CE3 3.73Å; Y385-W485 HydrophobicContact CD2-CG 4.08Å; Y385-W485 HydrophobicContact CD2-CZ3 4.48Å; Y385-W485 HydrophobicContact CE1-CB 4.11Å; Y385-W485 HydrophobicContact CE2-CB 4.35Å; Y385-W485 HydrophobicContact CG-CB 3.83Å; Y385-W485 AromaticContact CG-CD2 3.73Å; Y385-W485 HydrophobicContact CG-CD2 3.73Å; Y385-W485 HydrophobicContact CG-CE3 4.01Å; Y385-W485 AromaticContact CG-CG 3.62Å; Y385-W485 HydrophobicContact CG-CG 3.62Å; Q386-W485 HydrophobicContact CB-CZ2 4.42Å; Q386-W485 HydrophobicContact CG-CH2 3.57Å; Q386-W485 HydrophobicContact CG-CZ2 3.44Å; Q386-W485 VanDerWaalsContact CG-CZ2 3.44Å; D389-W485 PolarHBondContact OD1-NE1 3.31Å; D389-W485 PolarHBondContact OD2-NE1 3.34Å; L481-W485 PolarHBondContact O-N 3.19Å; L481-W485 VanDerWaalsContact O-N 3.09Å; Y482-W485 AromaticContact CE2-CD1 3.86Å; Y482-W485 PolarHBondContact O-N 2.98Å; Y482-W485 WeakPolarHBondContact O-CB 3.24Å; A483-W485 VanDerWaalsContact C-N 3.33Å; A483-W485 PolarHBondContact O-N 3.19Å; W485-E487 PolarHBondContact O-N 3.24Å; W485-E487 VanDerWaalsContact C-N 3.32Å; W485-A488 WeakPolarHBondContact O-CB 3.4Å; W485-A488 PolarHBondContact O-N 3.23Å; W485-A488 VanDerWaalsContact O-N 3.13Å; W485-V489 HydrophobicContact CZ3-CG2 4.18Å; W485-V489 PolarHBondContact O-N 3.1Å; W485-V489 WeakPolarHBondContact O-CG2 3.47Å; W485-V489 HydrophobicContact CZ2-CG2 3.31Å; W485-V489 HydrophobicContact CH2-CG2 3.76Å; W485-V489 HydrophobicContact CE3-CG2 4.21Å; W485-V489 HydrophobicContact CD2-CG2 3.83Å
486Q98.5Very high97.7Very high53 Ų5360 Ų6025%0.24831%0.309CS..Hα-helixtrans-59.1-43.4178.9-72.3-62.2-5100111.5Y354 D389 Y482 A483 A488 V489 Q490Y354-Q486 PolarHBondContact OH-NE2 3.32Å; D389-Q486 PolarHBondContact OD1-NE2 3.21Å; Y482-Q486 HydrophobicContact CD1-CG 4.29Å; Y482-Q486 HydrophobicContact CE1-CG 4.01Å; Y482-Q486 WeakPolarHBondContact O-CG 3.29Å; Y482-Q486 PolarHBondContact O-N 3.34Å; Y482-Q486 PolarHBondContact OH-NE2 3Å; Y482-Q486 VanDerWaalsContact OH-NE2 3.16Å; A483-Q486 PolarHBondContact O-N 3.28Å; Q486-A488 PolarHBondContact O-N 2.99Å; Q486-V489 PolarHBondContact O-N 3.39Å; Q486-Q490 VanDerWaalsContact O-CG 3.3Å; Q486-Q490 WeakPolarHBondContact O-CG 3.44Å; Q486-Q490 PolarHBondContact O-N 3.29Å
487E98.3Very high97.3Very high148 Ų14859.1 Ų59.169%0.69230%0.301SS*.Hα-helixtrans-60.5-43.5174.3-71.1-173.5-167.800112.3A483 G484 W485 V489 Q490 A491A483-E487 PolarHBondContact O-N 3.1Å; G484-E487 PolarHBondContact O-N 3.4Å; W485-E487 PolarHBondContact O-N 3.24Å; W485-E487 VanDerWaalsContact C-N 3.32Å; E487-V489 PolarHBondContact O-N 3.02Å; E487-Q490 PolarHBondContact O-N 2.6Å; E487-A491 WeakPolarHBondContact O-CB 2.79Å; E487-A491 PolarHBondContact O-N 3.32Å
488A98.7Very high96.5Very high5 Ų561.5 Ų61.54%0.04131%0.307CS..Hα-helixtrans-62.6-40.4177.900000112.5Y342 V344 F364 G484 W485 Q486 T492Y342-A488 HydrophobicContact CG-CB 4.11Å; V344-A488 HydrophobicContact CG2-CB 3.99Å; F364-A488 HydrophobicContact CD2-CB 3.79Å; F364-A488 HydrophobicContact CE2-CB 4.34Å; F364-A488 WeakPolarHBondContact CE2-O 3.48Å; F364-A488 HydrophobicContact CG-CB 4.42Å; G484-A488 PolarHBondContact O-N 3.01Å; W485-A488 WeakPolarHBondContact O-CB 3.4Å; W485-A488 PolarHBondContact O-N 3.23Å; W485-A488 VanDerWaalsContact O-N 3.13Å; Q486-A488 PolarHBondContact O-N 2.99Å; A488-T492 WeakPolarHBondContact O-CB 3.25Å; A488-T492 PolarHBondContact O-N 3.05Å; A488-T492 PolarHBondContact O-OG1 3.44Å
489V98.4Very high95.6Very high0 Ų065.8 Ų65.80%034%0.335CS..Hα-helixtrans-67.4-45176.2177.90000111.1V344 L350 Y354 W485 Q486 E487 A491 T492 M493V344-V489 HydrophobicContact CG1-CG2 4.32Å; V344-V489 HydrophobicContact CG2-CG2 4.28Å; L350-V489 HydrophobicContact CD1-CG1 3.84Å; Y354-V489 HydrophobicContact CD1-CG1 3.95Å; Y354-V489 HydrophobicContact CD2-CG1 4.34Å; Y354-V489 HydrophobicContact CE1-CB 4.49Å; Y354-V489 HydrophobicContact CE1-CG1 3.53Å; Y354-V489 HydrophobicContact CE2-CG1 3.95Å; Y354-V489 HydrophobicContact CG-CG1 4.33Å; W485-V489 HydrophobicContact CZ3-CG2 4.18Å; W485-V489 PolarHBondContact O-N 3.1Å; W485-V489 WeakPolarHBondContact O-CG2 3.47Å; W485-V489 HydrophobicContact CZ2-CG2 3.31Å; W485-V489 HydrophobicContact CH2-CG2 3.76Å; W485-V489 HydrophobicContact CE3-CG2 4.21Å; W485-V489 HydrophobicContact CD2-CG2 3.83Å; Q486-V489 PolarHBondContact O-N 3.39Å; E487-V489 PolarHBondContact O-N 3.02Å; V489-A491 VanDerWaalsContact C-N 3.33Å; V489-A491 PolarHBondContact O-N 2.8Å; V489-T492 VanDerWaalsContact O-CB 3.3Å; V489-T492 WeakPolarHBondContact O-CB 3.41Å; V489-T492 PolarHBondContact O-N 3.35Å; V489-T492 VanDerWaalsContact O-N 3.1Å; V489-M493 HydrophobicContact CG1-CE 4.15Å; V489-M493 PolarHBondContact O-N 3.19Å
490Q98Very high94.8Very high95 Ų9571.5 Ų71.544%0.44436%0.356SS..Hα-helixtrans-58.7-45.1176.4-68.7-61-31.600111.7Q486 E487 T492 M493 Q494Q486-Q490 VanDerWaalsContact O-CG 3.3Å; Q486-Q490 WeakPolarHBondContact O-CG 3.44Å; Q486-Q490 PolarHBondContact O-N 3.29Å; E487-Q490 PolarHBondContact O-N 2.6Å; Q490-T492 VanDerWaalsContact C-N 3.3Å; Q490-T492 PolarHBondContact O-N 3.45Å; Q490-M493 PolarHBondContact O-N 3.38Å; Q490-M493 HydrophobicContact CG-CE 4.48Å; Q490-M493 VanDerWaalsContact CD-CE 3.47Å; Q490-M493 VanDerWaalsContact NE2-CE 3.35Å; Q490-Q494 WeakPolarHBondContact O-CG 3.49Å; Q490-Q494 PolarHBondContact O-N 3.01Å
491A98.3Very high93.7Very high44 Ų4475.9 Ų75.936%0.36437%0.373SS..Hα-helixtrans-61.4-38175.400000112.4F364 E487 V489 Q494F364-A491 HydrophobicContact CD1-CB 4.48Å; F364-A491 HydrophobicContact CE1-CB 3.71Å; F364-A491 HydrophobicContact CE2-CB 4.45Å; F364-A491 HydrophobicContact CZ-CB 3.69Å; E487-A491 WeakPolarHBondContact O-CB 2.79Å; E487-A491 PolarHBondContact O-N 3.32Å; V489-A491 VanDerWaalsContact C-N 3.33Å; V489-A491 PolarHBondContact O-N 2.8Å; A491-Q494 PolarHBondContact O-N 3.38Å
492T98.4Very high91.9Very high2 Ų287.8 Ų87.81%0.01242%0.424CS..Hα-helixtrans-60.9-44.7175.4-57.80000111.5V344 A359 R360 A362 F364 A488 V489 Q490 Q494 Y495V344-T492 HydrophobicContact CB-CG2 4.43Å; V344-T492 HydrophobicContact CG1-CG2 3.98Å; A359-T492 HydrophobicContact CB-CG2 4.41Å; R360-T492 WeakPolarHBondContact O-CG2 3.42Å; A362-T492 HydrophobicContact CB-CG2 3.96Å; F364-T492 WeakPolarHBondContact CE2-OG1 3.42Å; A488-T492 WeakPolarHBondContact O-CB 3.25Å; A488-T492 PolarHBondContact O-N 3.05Å; A488-T492 PolarHBondContact O-OG1 3.44Å; V489-T492 VanDerWaalsContact O-CB 3.3Å; V489-T492 WeakPolarHBondContact O-CB 3.41Å; V489-T492 PolarHBondContact O-N 3.35Å; V489-T492 VanDerWaalsContact O-N 3.1Å; Q490-T492 VanDerWaalsContact C-N 3.3Å; Q490-T492 PolarHBondContact O-N 3.45Å; T492-Q494 PolarHBondContact O-N 3.23Å; T492-Y495 PolarHBondContact O-N 3.22Å
493M97.1Very high91.6Very high30 Ų3090.3 Ų90.315%0.14844%0.438CS..Hα-helixtrans-66.9-21.5-179.9-66.9-171.7-66.400113L350 Y354 D356 V489 Q490 Y495 K496L350-M493 HydrophobicContact CD1-CG 3.75Å; L350-M493 HydrophobicContact CD1-SD 4.19Å; Y354-M493 HydrophobicContact CD1-CE 4.08Å; Y354-M493 HydrophobicContact CD1-SD 4.01Å; Y354-M493 HydrophobicContact CG-SD 4.39Å; D356-M493 HydrophobicContact CB-CG 4.48Å; D356-M493 HydrophobicContact CB-SD 4.4Å; D356-M493 VanDerWaalsContact OD2-CG 3.3Å; D356-M493 WeakPolarHBondContact OD2-CG 3.31Å; V489-M493 HydrophobicContact CG1-CE 4.15Å; V489-M493 PolarHBondContact O-N 3.19Å; Q490-M493 PolarHBondContact O-N 3.38Å; Q490-M493 HydrophobicContact CG-CE 4.48Å; Q490-M493 VanDerWaalsContact CD-CE 3.47Å; Q490-M493 VanDerWaalsContact NE2-CE 3.35Å; M493-Y495 PolarHBondContact O-N 3.28Å; M493-Y495 VanDerWaalsContact C-N 3.33Å; M493-K496 WeakPolarHBondContact O-CE 3.46Å; M493-K496 PolarHBondContact O-NZ 3.25Å; M493-K496 VanDerWaalsContact O-NZ 3.07Å
494Q97.3Very high91.2Very high150 Ų15092.7 Ų92.770%0.70144%0.441SS*.Hα-helixtrans-73.7-20.9175-61.6-53.3-50.200113.8Q490 A491 T492 K496Q490-Q494 WeakPolarHBondContact O-CG 3.49Å; Q490-Q494 PolarHBondContact O-N 3.01Å; A491-Q494 PolarHBondContact O-N 3.38Å; T492-Q494 PolarHBondContact O-N 3.23Å; Q494-K496 PolarHBondContact O-N 3.43Å
495Y95.2Very high90.8Very high145 Ų14596.9 Ų96.957%0.56946%0.456SS*.  trans-85.3104.6179.9-177.1-98.5000111.3T492 M493 H497T492-Y495 PolarHBondContact O-N 3.22Å; M493-Y495 PolarHBondContact O-N 3.28Å; M493-Y495 VanDerWaalsContact C-N 3.33Å; Y495-H497 HydrophobicContact CE1-CB 4.32Å; Y495-H497 HydrophobicContact CE2-CB 3.97Å
496K92.3Very high90.3Very high70 Ų70102.5 Ų102.530%0.30448%0.483SS..  trans-122.923.3-175.6-60.2-59.1-170.6-146.20114.7D356 Q358 M493 Q494 Q498D356-K496 IonicContact OD1-NZ 3.49Å; D356-K496 PolarHBondContact OD1-NZ 3.41Å; D356-K496 IonicContact OD2-NZ 3.35Å; D356-K496 PolarHBondContact OD2-NZ 3.15Å; Q358-K496 HydrophobicContact CB-CD 3.6Å; M493-K496 WeakPolarHBondContact O-CE 3.46Å; M493-K496 PolarHBondContact O-NZ 3.25Å; M493-K496 VanDerWaalsContact O-NZ 3.07Å; Q494-K496 PolarHBondContact O-N 3.43Å; K496-Q498 PolarHBondContact O-N 3.18Å
497H90Very high89.8Confident118 Ų118105.6 Ų105.655%0.54650%0.498SS..  trans-63123-176.1179.665.1000111.7Y495Y495-H497 HydrophobicContact CE1-CB 4.32Å; Y495-H497 HydrophobicContact CE2-CB 3.97Å
498Q80.5Confident89.3Confident120 Ų120102.8 Ų102.856%0.56149%0.485SS*.  trans-105.4112.2170.6-64.3-66.2-14.900108.6K496K496-Q498 PolarHBondContact O-N 3.18Å
499P78.7Confident88.6Confident92 Ų92109.8 Ų109.860%0.59752%0.516SS*.PPolyproline II helixtrans-64.8145.1174.828.3-33000109.4
500K80.8Confident87.8Confident197 Ų197118.2 Ų118.286%0.85756%0.556SS**PPolyproline II helixtrans-64.1137.9170.6-65-175.7178.4-175.80109.2K502K500-K502 PolarHBondContact O-N 3.24Å
501E73.7Confident87Confident198 Ų198120.2 Ų120.293%0.92557%0.565SS**PPolyproline II helixtrans-56.6135.7170.1-65.7-169.6155.900109.6
502K61.3Low85.9Confident276 Ų276127.1 Ų127.1100%1.258%0.584SS**  trans-86.30-178.6-84.4-170.9178.2179.50112.2K500K500-K502 PolarHBondContact O-N 3.24Å

Retrieved 502 of 502 residues in 421.8 ms (Link to these results)