A0A077ZIL1_TRITR Loading...

dihydroxy-acid dehydratase

AlphaFold DB , UniProt , Accession A0A077ZIL1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 603 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M93.6Very high97.8Very high106 Ų10659 Ų5952%0.52229%0.291SS..  0139.80-82.9-44-64.600110.8L5 L6 G364M1-L5 HydrophobicContact CE-CD1 4.05Å; M1-L5 HydrophobicContact CE-CD2 3.45Å; M1-L5 VanDerWaalsContact CE-CD2 3.45Å; M1-L5 HydrophobicContact CE-CG 4.28Å; M1-L6 HydrophobicContact CB-CD1 3.73Å; M1-L6 HydrophobicContact CB-CD2 4.16Å; M1-L6 HydrophobicContact CB-CG 3.93Å; M1-L6 HydrophobicContact CG-CD2 4.44Å; M1-G364 WeakPolarHBondContact CE-O 3.15Å; M1-G364 VanDerWaalsContact SD-C 3.56Å; M1-G364 WeakPolarHBondContact SD-CA 3.39Å; M1-G364 VanDerWaalsContact SD-O 3.42Å
2N97.1Very high97.9Very high34 Ų3454.1 Ų54.118%0.18227%0.267CS..  trans-65.2128.7176.2-176.9-63.2000110.4Q4 L5 L6 G364 L365N2-Q4 VanDerWaalsContact C-N 3.33Å; N2-Q4 PolarHBondContact O-N 2.93Å; N2-Q4 WeakPolarHBondContact OD1-CB 3.09Å; N2-Q4 PolarHBondContact OD1-N 3.14Å; N2-L5 HydrophobicContact CB-CB 4.21Å; N2-L5 PolarHBondContact O-N 3.46Å; N2-L5 PolarHBondContact OD1-N 3.18Å; N2-L6 PolarHBondContact O-N 3.33Å; N2-L6 VanDerWaalsContact O-N 3.16Å; N2-G364 WeakPolarHBondContact CB-O 3.39Å; N2-G364 PolarHBondContact N-O 3.16Å; N2-L365 HydrophobicContact CB-CD2 3.85Å
3P97.9Very high98Very high106 Ų10654.2 Ų54.269%0.68827%0.268SS*.Hα-helixtrans-60.8-36.3-177.2-25.134.2000114.5L6 R7P3-L6 PolarHBondContact O-N 2.68Å; P3-R7 WeakPolarHBondContact O-CB 3.35Å; P3-R7 PolarHBondContact O-N 3.33Å
4Q97.5Very high98.1Very high38 Ų3858 Ų5818%0.17829%0.285CS..Hα-helixtrans-69.1-43.6-179.3179.173.7-19.600111.2N2 L6 R7 V8 D325 V329N2-Q4 VanDerWaalsContact C-N 3.33Å; N2-Q4 PolarHBondContact O-N 2.93Å; N2-Q4 WeakPolarHBondContact OD1-CB 3.09Å; N2-Q4 PolarHBondContact OD1-N 3.14Å; Q4-L6 VanDerWaalsContact C-N 3.31Å; Q4-L6 PolarHBondContact O-N 3.35Å; Q4-R7 VanDerWaalsContact CD-NH2 3.26Å; Q4-R7 WeakPolarHBondContact O-CB 3.44Å; Q4-R7 PolarHBondContact O-N 3Å; Q4-R7 VanDerWaalsContact O-N 3.15Å; Q4-V8 WeakPolarHBondContact O-CG2 3.47Å; Q4-V8 PolarHBondContact O-N 3.42Å; Q4-D325 PolarHBondContact NE2-O 3Å; Q4-V329 HydrophobicContact CB-CB 4.41Å; Q4-V329 HydrophobicContact CB-CG1 3.69Å; Q4-V329 HydrophobicContact CB-CG2 4.03Å; Q4-V329 HydrophobicContact CG-CB 4.41Å; Q4-V329 HydrophobicContact CG-CG1 3.7Å; Q4-V329 HydrophobicContact CG-CG2 3.82Å
5L98.3Very high98.1Very high0 Ų059.1 Ų59.10%028%0.284CS..Hα-helixtrans-59.9-44.2175.8179.2158.1000111M1 N2 R7 V8 T9 V288 V292 L326 L365 H367M1-L5 HydrophobicContact CE-CD1 4.05Å; M1-L5 HydrophobicContact CE-CD2 3.45Å; M1-L5 VanDerWaalsContact CE-CD2 3.45Å; M1-L5 HydrophobicContact CE-CG 4.28Å; N2-L5 HydrophobicContact CB-CB 4.21Å; N2-L5 PolarHBondContact O-N 3.46Å; N2-L5 PolarHBondContact OD1-N 3.18Å; L5-R7 VanDerWaalsContact C-N 3.33Å; L5-R7 PolarHBondContact O-N 3.39Å; L5-V8 PolarHBondContact O-N 3.38Å; L5-T9 WeakPolarHBondContact O-CB 3.4Å; L5-T9 PolarHBondContact O-N 2.99Å; L5-T9 PolarHBondContact O-OG1 3.36Å; L5-V288 HydrophobicContact CD1-CG1 4.36Å; L5-V288 HydrophobicContact CD2-CG1 4.32Å; L5-V288 HydrophobicContact CG-CG1 4.06Å; L5-V292 HydrophobicContact CD1-CG2 4.03Å; L5-L326 HydrophobicContact CB-CD2 4.2Å; L5-L326 HydrophobicContact CG-CD2 4.12Å; L5-L365 HydrophobicContact CD1-CB 4.49Å; L5-L365 HydrophobicContact CD1-CD2 4.45Å; L5-L365 WeakPolarHBondContact CD1-O 3.47Å; L5-H367 VanDerWaalsContact CD2-CE1 3.47Å; L5-H367 WeakPolarHBondContact CD2-CE1 3.32Å; L5-H367 WeakPolarHBondContact CD2-NE2 3.34Å
6L98.5Very high98.1Very high64 Ų6455.4 Ų55.434%0.33527%0.267SS..Hα-helixtrans-61.4-41.6174.6-71.8175.8000111.9M1 N2 P3 Q4 T9 N10M1-L6 HydrophobicContact CB-CD1 3.73Å; M1-L6 HydrophobicContact CB-CD2 4.16Å; M1-L6 HydrophobicContact CB-CG 3.93Å; M1-L6 HydrophobicContact CG-CD2 4.44Å; N2-L6 PolarHBondContact O-N 3.33Å; N2-L6 VanDerWaalsContact O-N 3.16Å; P3-L6 PolarHBondContact O-N 2.68Å; Q4-L6 VanDerWaalsContact C-N 3.31Å; Q4-L6 PolarHBondContact O-N 3.35Å; L6-T9 PolarHBondContact O-N 3.35Å; L6-N10 WeakPolarHBondContact O-CB 3.15Å; L6-N10 VanDerWaalsContact O-CG 3.24Å; L6-N10 PolarHBondContact O-N 3.21Å; L6-N10 PolarHBondContact O-ND2 3.44Å
7R98.6Very high98.2Very high128 Ų12860.4 Ų60.448%0.48328%0.282SS..Hα-helixtrans-60.1-48176.9-173.2178.971.2118.311.2111.7P3 Q4 L5 N10 R11 D325P3-R7 WeakPolarHBondContact O-CB 3.35Å; P3-R7 PolarHBondContact O-N 3.33Å; Q4-R7 VanDerWaalsContact CD-NH2 3.26Å; Q4-R7 WeakPolarHBondContact O-CB 3.44Å; Q4-R7 PolarHBondContact O-N 3Å; Q4-R7 VanDerWaalsContact O-N 3.15Å; L5-R7 VanDerWaalsContact C-N 3.33Å; L5-R7 PolarHBondContact O-N 3.39Å; R7-N10 PolarHBondContact O-N 2.75Å; R7-R11 WeakPolarHBondContact O-CB 3.41Å; R7-R11 PolarHBondContact O-N 3.04Å; R7-D325 IonicContact NH2-OD1 3.23Å; R7-D325 IonicContact NH2-OD2 2.63Å
8V98.6Very high98.2Very high0 Ų066.4 Ų66.40%031%0.31CS..Hα-helixtrans-63.3-44.8177175.40000110.6Q4 L5 N10 R11 I12 D322 D325 L326Q4-V8 WeakPolarHBondContact O-CG2 3.47Å; Q4-V8 PolarHBondContact O-N 3.42Å; L5-V8 PolarHBondContact O-N 3.38Å; V8-N10 PolarHBondContact O-N 3.5Å; V8-R11 WeakPolarHBondContact O-CB 3.37Å; V8-R11 PolarHBondContact O-N 3.05Å; V8-I12 HydrophobicContact CG1-CD1 3.81Å; V8-I12 HydrophobicContact CG1-CG1 4.43Å; V8-I12 WeakPolarHBondContact O-CG1 3.36Å; V8-I12 PolarHBondContact O-N 3.46Å; V8-D322 HydrophobicContact CG1-CB 3.78Å; V8-D325 HydrophobicContact CG2-CB 3.59Å; V8-L326 HydrophobicContact CB-CD2 4.16Å; V8-L326 HydrophobicContact CB-CG 4.23Å; V8-L326 HydrophobicContact CG1-CD1 3.98Å; V8-L326 HydrophobicContact CG1-CD2 4.3Å; V8-L326 HydrophobicContact CG1-CG 3.92Å; V8-L326 HydrophobicContact CG2-CD2 4.34Å; V8-L326 HydrophobicContact CG2-CG 4.25Å
9T98.9Very high98.2Very high2 Ų265.7 Ų65.71%0.01231%0.311CS..Hα-helixtrans-58.5-47.7177.8-53.30000111.3L5 L6 R11 I12 I13 K285 V288 H367L5-T9 WeakPolarHBondContact O-CB 3.4Å; L5-T9 PolarHBondContact O-N 2.99Å; L5-T9 PolarHBondContact O-OG1 3.36Å; L6-T9 PolarHBondContact O-N 3.35Å; T9-R11 VanDerWaalsContact C-N 3.32Å; T9-R11 PolarHBondContact O-N 2.89Å; T9-I12 PolarHBondContact O-N 3.45Å; T9-I13 HydrophobicContact CG2-CD1 4.02Å; T9-I13 WeakPolarHBondContact O-CG1 3.45Å; T9-I13 PolarHBondContact O-N 2.88Å; T9-K285 HydrophobicContact CG2-CG 4.13Å; T9-V288 HydrophobicContact CG2-CG2 4.45Å; T9-H367 WeakPolarHBondContact CG2-NE2 3.41Å; T9-H367 PolarHBondContact OG1-CE1 3.01Å; T9-H367 PolarHBondContact OG1-NE2 3.36Å
10N98.8Very high98.3Very high97 Ų9763.1 Ų63.152%0.51930%0.298SS..Hα-helixtrans-64.9-36.2178.8-71.1-23.6000112.2L6 R7 V8 I13 E14L6-N10 WeakPolarHBondContact O-CB 3.15Å; L6-N10 VanDerWaalsContact O-CG 3.24Å; L6-N10 PolarHBondContact O-N 3.21Å; L6-N10 PolarHBondContact O-ND2 3.44Å; R7-N10 PolarHBondContact O-N 2.75Å; V8-N10 PolarHBondContact O-N 3.5Å; N10-I13 PolarHBondContact O-N 3.07Å; N10-E14 WeakPolarHBondContact O-CB 3.45Å; N10-E14 PolarHBondContact O-N 2.98Å
11R98.7Very high98.3Very high74 Ų7464 Ų6428%0.27931%0.311SS..Hα-helixtrans-62.2-42.9173-179174.567.8-156-0.3111.5R7 V8 T9 E14 R15 D321 D322 D325R7-R11 WeakPolarHBondContact O-CB 3.41Å; R7-R11 PolarHBondContact O-N 3.04Å; V8-R11 WeakPolarHBondContact O-CB 3.37Å; V8-R11 PolarHBondContact O-N 3.05Å; T9-R11 VanDerWaalsContact C-N 3.32Å; T9-R11 PolarHBondContact O-N 2.89Å; R11-E14 PolarHBondContact O-N 3.19Å; R11-R15 WeakPolarHBondContact O-CB 3.48Å; R11-R15 PolarHBondContact O-N 2.85Å; R11-D321 PolarHBondContact NH2-O 2.93Å; R11-D322 IonicContact CZ-OD1 2.74Å; R11-D322 IonicContact NE-OD1 2.86Å; R11-D322 PolarHBondContact NE-OD1 3.21Å; R11-D322 VanDerWaalsContact NE-OD1 3.09Å; R11-D322 IonicContact NH2-OD1 3.51Å; R11-D322 PolarHBondContact NH2-OD1 3.07Å; R11-D325 IonicContact CZ-OD2 3.69Å; R11-D325 IonicContact NH1-OD2 3.88Å; R11-D325 PolarHBondContact NH1-OD2 3.32Å; R11-D325 IonicContact NH2-OD2 3.17Å; R11-D325 PolarHBondContact NH2-OD2 3.36Å
12I98.9Very high98.5Very high0 Ų062 Ų620%031%0.311CS..Hα-helixtrans-63.7-45.8176.3-66.2163.6000110.4V8 T9 E14 R15 S16 E284 V288 I316 I318 D322V8-I12 HydrophobicContact CG1-CD1 3.81Å; V8-I12 HydrophobicContact CG1-CG1 4.43Å; V8-I12 WeakPolarHBondContact O-CG1 3.36Å; V8-I12 PolarHBondContact O-N 3.46Å; T9-I12 PolarHBondContact O-N 3.45Å; I12-E14 PolarHBondContact O-N 2.68Å; I12-R15 PolarHBondContact O-N 3.17Å; I12-S16 WeakPolarHBondContact O-CB 3.37Å; I12-S16 PolarHBondContact O-N 3.2Å; I12-S16 PolarHBondContact O-OG 3.25Å; I12-E284 HydrophobicContact CG2-CB 4.13Å; I12-E284 HydrophobicContact CG2-CG 3.95Å; I12-V288 HydrophobicContact CD1-CG2 3.6Å; I12-I316 HydrophobicContact CG2-CG2 3.71Å; I12-I318 HydrophobicContact CD1-CG2 3.75Å; I12-I318 HydrophobicContact CG1-CG2 3.99Å; I12-I318 HydrophobicContact CG2-CG2 3.89Å; I12-D322 HydrophobicContact CD1-CB 4.2Å
13I98.9Very high98.6Very high56 Ų5660.5 Ų60.529%0.28730%0.303SS..Hα-helixtrans-58-48.5176.8-69.4166000110.8T9 N10 S16 R17 E284T9-I13 HydrophobicContact CG2-CD1 4.02Å; T9-I13 WeakPolarHBondContact O-CG1 3.45Å; T9-I13 PolarHBondContact O-N 2.88Å; N10-I13 PolarHBondContact O-N 3.07Å; I13-S16 PolarHBondContact O-N 3.44Å; I13-R17 PolarHBondContact O-N 3.46Å; I13-E284 HydrophobicContact CG1-CB 3.7Å; I13-E284 HydrophobicContact CG1-CG 3.72Å
14E98.8Very high98.6Very high107 Ų10758.2 Ų58.250%0.529%0.285SS..Hα-helixtrans-61.2-49.9179.7-173.963.1-145.500111.2N10 R11 I12 S16 R17N10-E14 WeakPolarHBondContact O-CB 3.45Å; N10-E14 PolarHBondContact O-N 2.98Å; R11-E14 PolarHBondContact O-N 3.19Å; I12-E14 PolarHBondContact O-N 2.68Å; E14-S16 PolarHBondContact O-N 2.94Å; E14-R17 WeakPolarHBondContact O-CB 3.49Å; E14-R17 PolarHBondContact O-N 2.73Å; E14-R17 IonicContact OE1-CZ 3.2Å; E14-R17 IonicContact OE1-NH1 3.76Å; E14-R17 PolarHBondContact OE1-NH1 3.4Å; E14-R17 IonicContact OE1-NH2 2.61Å; E14-R17 IonicContact OE2-CZ 3.83Å; E14-R17 IonicContact OE2-NH1 2.69Å; E14-R17 PolarHBondContact OE2-NH1 2.71Å; E14-R17 IonicContact OE2-NH2 3.9Å; E14-R17 PolarHBondContact OE2-NH2 2.74Å
15R98.7Very high98.6Very high74 Ų7458.3 Ų58.328%0.27930%0.296SS..Hα-helixtrans-63.7-29.5179.8-173.6172.157.9-144.1-13.2112.7R11 I12 Q317 N319 D322R11-R15 WeakPolarHBondContact O-CB 3.48Å; R11-R15 PolarHBondContact O-N 2.85Å; I12-R15 PolarHBondContact O-N 3.17Å; R15-Q317 HydrophobicContact CG-CB 4.17Å; R15-Q317 PolarHBondContact NE-O 3.24Å; R15-Q317 VanDerWaalsContact NE-O 3.08Å; R15-Q317 PolarHBondContact NH2-O 3.14Å; R15-N319 PolarHBondContact NH1-ND2 3.39Å; R15-N319 PolarHBondContact NH1-OD1 3.32Å; R15-D322 IonicContact CZ-OD2 2.77Å; R15-D322 IonicContact NH1-OD1 3.78Å; R15-D322 IonicContact NH1-OD2 3.35Å; R15-D322 IonicContact NH2-OD1 3.71Å; R15-D322 PolarHBondContact NH2-OD1 3.34Å; R15-D322 IonicContact NH2-OD2 2.58Å; R15-D322 PolarHBondContact NH2-OD2 3.35Å
16S98.8Very high98.6Very high0 Ų064.1 Ų64.10%032%0.318CS..Hα-helixtrans-92.5-7.1-178.3-50.70000113.6I12 I13 E14 E18 T19 R20 Q317I12-S16 WeakPolarHBondContact O-CB 3.37Å; I12-S16 PolarHBondContact O-N 3.2Å; I12-S16 PolarHBondContact O-OG 3.25Å; I13-S16 PolarHBondContact O-N 3.44Å; E14-S16 PolarHBondContact O-N 2.94Å; S16-E18 VanDerWaalsContact C-N 3.33Å; S16-E18 PolarHBondContact O-N 2.86Å; S16-E18 VanDerWaalsContact O-N 3.15Å; S16-T19 PolarHBondContact O-N 3.29Å; S16-T19 VanDerWaalsContact O-N 3.17Å; S16-T19 PolarHBondContact O-OG1 2.66Å; S16-R20 WeakPolarHBondContact O-CB 3.47Å; S16-R20 PolarHBondContact O-N 2.82Å; S16-Q317 PolarHBondContact OG-N 3.08Å
17R98.8Very high98.5Very high141 Ų14161.3 Ų61.353%0.53230%0.303SS..Hα-helixtrans-49.2-50.3-167.1179.4-178.1-77.5143.26.9113.2I13 E14 S21I13-R17 PolarHBondContact O-N 3.46Å; E14-R17 WeakPolarHBondContact O-CB 3.49Å; E14-R17 PolarHBondContact O-N 2.73Å; E14-R17 IonicContact OE1-CZ 3.2Å; E14-R17 IonicContact OE1-NH1 3.76Å; E14-R17 PolarHBondContact OE1-NH1 3.4Å; E14-R17 IonicContact OE1-NH2 2.61Å; E14-R17 IonicContact OE2-CZ 3.83Å; E14-R17 IonicContact OE2-NH1 2.69Å; E14-R17 PolarHBondContact OE2-NH1 2.71Å; E14-R17 IonicContact OE2-NH2 3.9Å; E14-R17 PolarHBondContact OE2-NH2 2.74Å; R17-S21 WeakPolarHBondContact O-CB 3.42Å; R17-S21 PolarHBondContact O-N 3Å
18E98.6Very high98.2Very high168 Ų16859.3 Ų59.379%0.78530%0.299SS*.Hα-helixtrans-69.5-50-178.2-65.2-174.2171.500112S16 R20 S21 A22S16-E18 VanDerWaalsContact C-N 3.33Å; S16-E18 PolarHBondContact O-N 2.86Å; S16-E18 VanDerWaalsContact O-N 3.15Å; E18-R20 PolarHBondContact O-N 2.81Å; E18-S21 PolarHBondContact O-N 2.74Å; E18-A22 WeakPolarHBondContact O-CB 3.34Å; E18-A22 PolarHBondContact O-N 2.86Å
19T98.6Very high98Very high54 Ų5467.3 Ų67.333%0.33134%0.337SS..Hα-helixtrans-66.6-37.4-177.6480000112.4S16 Y23 G315 Q317S16-T19 PolarHBondContact O-N 3.29Å; S16-T19 VanDerWaalsContact O-N 3.17Å; S16-T19 PolarHBondContact O-OG1 2.66Å; T19-Y23 WeakPolarHBondContact O-CB 3.46Å; T19-Y23 PolarHBondContact O-N 3.17Å; T19-G315 CarbonylContact C-O 3.21Å; T19-G315 WeakPolarHBondContact CB-O 3.47Å; T19-G315 PolarHBondContact OG1-O 3.12Å; T19-Q317 VanDerWaalsContact CG2-NE2 3.28Å; T19-Q317 PolarHBondContact OG1-NE2 2.99Å
20R98.7Very high97.7Very high13 Ų1369 Ų695%0.04935%0.35CS..Hα-helixtrans-70.4-43.4177.3-176.860174.5164.56.3111.5S16 E18 Y23 L24 G279 I282 A314 G315S16-R20 WeakPolarHBondContact O-CB 3.47Å; S16-R20 PolarHBondContact O-N 2.82Å; E18-R20 PolarHBondContact O-N 2.81Å; R20-Y23 VanDerWaalsContact NH1-CD1 3.3Å; R20-Y23 VanDerWaalsContact NH1-CE1 3.33Å; R20-Y23 PolarHBondContact O-N 3.17Å; R20-L24 HydrophobicContact CG-CD1 4.17Å; R20-L24 WeakPolarHBondContact O-CG 3.26Å; R20-L24 PolarHBondContact O-N 3.24Å; R20-G279 PolarHBondContact NH1-O 2.92Å; R20-G279 PolarHBondContact NH2-O 3.46Å; R20-I282 PolarHBondContact NH1-O 2.75Å; R20-I282 VanDerWaalsContact NH1-O 3.16Å; R20-I282 PolarHBondContact NH2-O 3.46Å; R20-A314 VanDerWaalsContact CD-O 3.27Å; R20-A314 WeakPolarHBondContact CD-O 3.45Å; R20-A314 PolarHBondContact NH1-O 2.91Å; R20-G315 PolarHBondContact N-O 2.8Å; R20-G315 VanDerWaalsContact N-O 3.16Å
21S98.7Very high97.2Very high82 Ų8268.8 Ų68.857%0.57335%0.345SS*.Hα-helixtrans-60.3-46.4175-1780000111.4R17 E18 Y23 L24 G25R17-S21 WeakPolarHBondContact O-CB 3.42Å; R17-S21 PolarHBondContact O-N 3Å; E18-S21 PolarHBondContact O-N 2.74Å; S21-Y23 VanDerWaalsContact C-N 3.35Å; S21-Y23 PolarHBondContact O-N 2.78Å; S21-L24 PolarHBondContact O-N 3.41Å; S21-G25 PolarHBondContact O-N 3.49Å
22A98.5Very high96.3Very high63 Ų6366.4 Ų66.452%0.52134%0.339SS..Hα-helixtrans-60.2-43.8175.500000112E18 G25 R26E18-A22 WeakPolarHBondContact O-CB 3.34Å; E18-A22 PolarHBondContact O-N 2.86Å; A22-G25 PolarHBondContact O-N 2.81Å; A22-R26 PolarHBondContact O-N 2.93Å; A22-R26 VanDerWaalsContact O-N 3.09Å
23Y98.6Very high95.2Very high4 Ų472.3 Ų72.32%0.01638%0.38CS..Hα-helixtrans-59.5-51.5175.4175.1-95.5000112.1T19 R20 S21 G25 R26 I27 L166 G169 G279 A313 A314T19-Y23 WeakPolarHBondContact O-CB 3.46Å; T19-Y23 PolarHBondContact O-N 3.17Å; R20-Y23 VanDerWaalsContact NH1-CD1 3.3Å; R20-Y23 VanDerWaalsContact NH1-CE1 3.33Å; R20-Y23 PolarHBondContact O-N 3.17Å; S21-Y23 VanDerWaalsContact C-N 3.35Å; S21-Y23 PolarHBondContact O-N 2.78Å; Y23-G25 VanDerWaalsContact C-N 3.27Å; Y23-G25 PolarHBondContact O-N 2.82Å; Y23-R26 WeakPolarHBondContact O-CB 3.2Å; Y23-R26 PolarHBondContact O-N 3.22Å; Y23-I27 HydrophobicContact CD1-CG1 4.11Å; Y23-I27 HydrophobicContact CE1-CD1 4.19Å; Y23-I27 HydrophobicContact CE1-CG1 3.67Å; Y23-I27 HydrophobicContact CE2-CD1 4.06Å; Y23-I27 HydrophobicContact CE2-CG1 4.38Å; Y23-I27 WeakPolarHBondContact O-CG1 3.09Å; Y23-I27 PolarHBondContact O-N 2.87Å; Y23-L166 VanDerWaalsContact CE2-O 3.28Å; Y23-L166 WeakPolarHBondContact CE2-O 3.35Å; Y23-L166 PolarHBondContact OH-O 2.87Å; Y23-G169 WeakPolarHBondContact OH-CA 3.46Å; Y23-G279 WeakPolarHBondContact OH-CA 3.43Å; Y23-A313 WeakPolarHBondContact CE2-O 3.42Å; Y23-A314 VanDerWaalsContact CD1-O 3.26Å; Y23-A314 WeakPolarHBondContact CD1-O 3.41Å; Y23-A314 HydrophobicContact CE1-CB 4.47Å
24L98.4Very high94.1Very high58 Ų5873 Ų7330%0.30439%0.387SS..Hα-helixtrans-63.3-34179.4-69.7173000112.2R20 S21 I27 E28 K280R20-L24 HydrophobicContact CG-CD1 4.17Å; R20-L24 WeakPolarHBondContact O-CG 3.26Å; R20-L24 PolarHBondContact O-N 3.24Å; S21-L24 PolarHBondContact O-N 3.41Å; L24-I27 PolarHBondContact O-N 2.89Å; L24-E28 PolarHBondContact O-N 2.9Å; L24-K280 HydrophobicContact CD2-CG 4.17Å
25G98.2Very high93.3Very high40 Ų4067.9 Ų67.941%0.41236%0.363SS..Hα-helixtrans-58.8-44.6170.800000112.4S21 A22 Y23 I27 E28 Q29S21-G25 PolarHBondContact O-N 3.49Å; A22-G25 PolarHBondContact O-N 2.81Å; Y23-G25 VanDerWaalsContact C-N 3.27Å; Y23-G25 PolarHBondContact O-N 2.82Å; G25-I27 VanDerWaalsContact C-N 3.33Å; G25-I27 PolarHBondContact O-N 2.95Å; G25-E28 PolarHBondContact O-N 3.14Å; G25-Q29 WeakPolarHBondContact O-CB 3.36Å; G25-Q29 PolarHBondContact O-N 2.87Å
26R97Very high92.4Very high121 Ų12165 Ų6546%0.45735%0.353SS..Hα-helixtrans-61.5-40.7173.3-67-170.4-68-165.9-5.1111.8A22 Y23 Q29 A30 F603A22-R26 PolarHBondContact O-N 2.93Å; A22-R26 VanDerWaalsContact O-N 3.09Å; Y23-R26 WeakPolarHBondContact O-CB 3.2Å; Y23-R26 PolarHBondContact O-N 3.22Å; R26-Q29 PolarHBondContact O-N 3.19Å; R26-A30 WeakPolarHBondContact O-CB 3.23Å; R26-A30 PolarHBondContact O-N 2.81Å; R26-F603 PolarHBondContact NH1-OXT 3.16Å; R26-F603 PolarHBondContact NH2-OXT 3.14Å
27I95.9Very high91.9Very high5 Ų565 Ų653%0.02635%0.353CS..Hα-helixtrans-64.5-44.7179.3-62.2-35.8000111.4Y23 L24 G25 Q29 A30 K31 H170 W275 P277Y23-I27 HydrophobicContact CD1-CG1 4.11Å; Y23-I27 HydrophobicContact CE1-CD1 4.19Å; Y23-I27 HydrophobicContact CE1-CG1 3.67Å; Y23-I27 HydrophobicContact CE2-CD1 4.06Å; Y23-I27 HydrophobicContact CE2-CG1 4.38Å; Y23-I27 WeakPolarHBondContact O-CG1 3.09Å; Y23-I27 PolarHBondContact O-N 2.87Å; L24-I27 PolarHBondContact O-N 2.89Å; G25-I27 VanDerWaalsContact C-N 3.33Å; G25-I27 PolarHBondContact O-N 2.95Å; I27-Q29 VanDerWaalsContact C-N 3.34Å; I27-A30 PolarHBondContact O-N 3Å; I27-K31 PolarHBondContact O-N 2.93Å; I27-K31 VanDerWaalsContact O-N 3.17Å; I27-H170 HydrophobicContact CG2-CB 4.04Å; I27-W275 HydrophobicContact CG2-CH2 4.43Å; I27-P277 HydrophobicContact CG2-CG 4.4Å
28E94.3Very high91.3Very high87 Ų8760.6 Ų60.641%0.40734%0.344SS..Hα-helixtrans-69-33.7177.6-162.864.8-152.400111.7L24 G25 K31 K280L24-E28 PolarHBondContact O-N 2.9Å; G25-E28 PolarHBondContact O-N 3.14Å; E28-K31 VanDerWaalsContact O-CB 3.3Å; E28-K31 WeakPolarHBondContact O-CB 3.42Å; E28-K31 PolarHBondContact O-N 3.31Å; E28-K31 VanDerWaalsContact OE1-CD 3.22Å; E28-K31 WeakPolarHBondContact OE1-CD 3.39Å; E28-K31 IonicContact OE1-NZ 2.72Å; E28-K31 PolarHBondContact OE1-NZ 3.24Å; E28-K280 IonicContact OE2-NZ 2.87Å; E28-K280 PolarHBondContact OE2-NZ 3.44Å
29Q93.8Very high90.6Very high168 Ų16858.9 Ų58.979%0.78534%0.336SS*.Hα-helixtrans-66.8-36173.9-173.5179.811.900112.6G25 R26 I27 K31G25-Q29 WeakPolarHBondContact O-CB 3.36Å; G25-Q29 PolarHBondContact O-N 2.87Å; R26-Q29 PolarHBondContact O-N 3.19Å; I27-Q29 VanDerWaalsContact C-N 3.34Å; Q29-K31 VanDerWaalsContact C-N 3.31Å
30A92.3Very high90.2Very high36 Ų3657.9 Ų57.930%0.29833%0.328SS..Hα-helixtrans-78.6-14.117900000113.4R26 I27 H36 H170R26-A30 WeakPolarHBondContact O-CB 3.23Å; R26-A30 PolarHBondContact O-N 2.81Å; I27-A30 PolarHBondContact O-N 3Å; A30-H36 PolarHBondContact O-CE1 3.15Å; A30-H36 VanDerWaalsContact O-CE1 3.31Å; A30-H170 HydrophobicContact CB-CB 3.85Å; A30-H170 WeakPolarHBondContact CB-ND1 3.36Å
31K88.2Confident89.8Confident93 Ų9360.2 Ų60.240%0.40435%0.351SS..  trans-60.4135.2177.6-176.5-171.4-177.1178.30111.2I27 E28 Q29 W275I27-K31 PolarHBondContact O-N 2.93Å; I27-K31 VanDerWaalsContact O-N 3.17Å; E28-K31 VanDerWaalsContact O-CB 3.3Å; E28-K31 WeakPolarHBondContact O-CB 3.42Å; E28-K31 PolarHBondContact O-N 3.31Å; E28-K31 VanDerWaalsContact OE1-CD 3.22Å; E28-K31 WeakPolarHBondContact OE1-CD 3.39Å; E28-K31 IonicContact OE1-NZ 2.72Å; E28-K31 PolarHBondContact OE1-NZ 3.24Å; Q29-K31 VanDerWaalsContact C-N 3.31Å; K31-W275 HydrophobicContact CB-CH2 3.86Å; K31-W275 HydrophobicContact CB-CZ2 4.02Å; K31-W275 HydrophobicContact CD-CE3 4.06Å; K31-W275 HydrophobicContact CD-CH2 3.56Å; K31-W275 HydrophobicContact CD-CZ2 4.14Å; K31-W275 HydrophobicContact CD-CZ3 3.5Å; K31-W275 HydrophobicContact CG-CH2 3.67Å; K31-W275 HydrophobicContact CG-CZ2 3.76Å; K31-W275 HydrophobicContact CG-CZ3 4.07Å
32T80.8Confident89.5Confident24 Ų2461.6 Ų61.615%0.14736%0.359CS..  trans-106.9150.3172.855.60000111.4T34 H36T32-T34 VanDerWaalsContact C-N 3.3Å; T32-T34 VanDerWaalsContact CB-O 3.29Å; T32-T34 WeakPolarHBondContact CB-O 3.48Å; T32-T34 PolarHBondContact OG1-O 2.94Å; T32-H36 WeakPolarHBondContact CG2-ND1 3.49Å; T32-H36 PolarHBondContact OG1-NE2 3.37Å
33S74.2Confident89.3Confident125 Ų12560.6 Ų60.687%0.87435%0.354SS*.SBendtrans-82.8-9.2173.154.80000113.3
34T76.1Confident89Confident69 Ų6965.1 Ų65.142%0.42338%0.379SS..SBendtrans-139.5-165.5177.667.70000108.7T32 S38T32-T34 VanDerWaalsContact C-N 3.3Å; T32-T34 VanDerWaalsContact CB-O 3.29Å; T32-T34 WeakPolarHBondContact CB-O 3.48Å; T32-T34 PolarHBondContact OG1-O 2.94Å; T34-S38 PolarHBondContact OG1-OG 3.21Å; T34-S38 VanDerWaalsContact OG1-OG 3.09Å
35V81.7Confident88.7Confident0 Ų063 Ų630%037%0.368CS..  trans-63.6141.5173.3-60.50000112.1R37 S38 M63 D146 N271V35-R37 VanDerWaalsContact C-N 3.27Å; V35-R37 HydrophobicContact CB-CG 4.28Å; V35-R37 HydrophobicContact CG2-CG 3.78Å; V35-R37 PolarHBondContact O-N 2.99Å; V35-S38 VanDerWaalsContact O-CB 3.31Å; V35-S38 WeakPolarHBondContact O-CB 3.38Å; V35-S38 PolarHBondContact O-N 3.36Å; V35-S38 VanDerWaalsContact O-N 3.12Å; V35-S38 PolarHBondContact O-OG 2.77Å; V35-M63 WeakPolarHBondContact CG1-O 3.34Å; V35-M63 HydrophobicContact CG2-CB 3.78Å; V35-M63 HydrophobicContact CG2-CG 4.49Å; V35-M63 VanDerWaalsContact CG2-O 3.24Å; V35-M63 WeakPolarHBondContact CG2-O 3.36Å; V35-M63 HydrophobicContact CG2-SD 4.08Å; V35-D146 WeakPolarHBondContact CA-OD1 3.41Å; V35-D146 VanDerWaalsContact CB-OD1 3.3Å; V35-D146 WeakPolarHBondContact CB-OD1 3.49Å; V35-N271 WeakPolarHBondContact CG1-ND2 3.48Å
36H81.3Confident88.5Confident13 Ų1363.2 Ų63.26%0.0637%0.366CS..G310 helixtrans-58.3-40.3-176.4-82.7-87.3000112.8A30 T32 S38 Q39 F145 D146 H170A30-H36 PolarHBondContact O-CE1 3.15Å; A30-H36 VanDerWaalsContact O-CE1 3.31Å; T32-H36 WeakPolarHBondContact CG2-ND1 3.49Å; T32-H36 PolarHBondContact OG1-NE2 3.37Å; H36-S38 PolarHBondContact O-N 2.83Å; H36-Q39 PolarHBondContact O-N 2.79Å; H36-F145 PolarHBondContact CD2-O 2.98Å; H36-D146 IonicContact CD2-OD1 3.24Å; H36-D146 PolarHBondContact N-OD1 3.34Å; H36-H170 AromaticContact CE1-CD2 3.25Å; H36-H170 PolarHBondContact CE1-CD2 3.43Å; H36-H170 AromaticContact CE1-NE2 3.55Å; H36-H170 AromaticContact NE2-CD2 3.55Å
37R87.7Confident88.5Confident0 Ų065.1 Ų65.10%038%0.379CS..G310 helixtrans-63.3-14.3-178.470.4-178.5-179.4-82.9-1.1114.2V35 Q39 L40 L45 L60 M63 R65 D146V35-R37 VanDerWaalsContact C-N 3.27Å; V35-R37 HydrophobicContact CB-CG 4.28Å; V35-R37 HydrophobicContact CG2-CG 3.78Å; V35-R37 PolarHBondContact O-N 2.99Å; R37-Q39 PolarHBondContact O-N 2.82Å; R37-Q39 VanDerWaalsContact O-N 3.14Å; R37-L40 HydrophobicContact CB-CD1 4.09Å; R37-L40 WeakPolarHBondContact O-CB 3.3Å; R37-L40 PolarHBondContact O-N 3.01Å; R37-L45 HydrophobicContact CB-CD2 3.84Å; R37-L45 HydrophobicContact CG-CD2 4.15Å; R37-L45 WeakPolarHBondContact O-CD2 3.46Å; R37-L60 PolarHBondContact NE-O 2.92Å; R37-L60 PolarHBondContact NH2-O 3.49Å; R37-M63 HydrophobicContact CG-SD 3.76Å; R37-R65 VanDerWaalsContact CZ-O 3.26Å; R37-R65 PolarHBondContact NH1-O 3.26Å; R37-R65 PolarHBondContact NH2-O 2.89Å; R37-D146 IonicContact NH1-OD2 3.7Å; R37-D146 PolarHBondContact NH1-OD2 3.49Å
38S84.8Confident88.4Confident50 Ų5065.9 Ų65.935%0.3539%0.389SS..G310 helixtrans-61.2-20.4176.664.10000113.2T34 V35 H36T34-S38 PolarHBondContact OG1-OG 3.21Å; T34-S38 VanDerWaalsContact OG1-OG 3.09Å; V35-S38 VanDerWaalsContact O-CB 3.31Å; V35-S38 WeakPolarHBondContact O-CB 3.38Å; V35-S38 PolarHBondContact O-N 3.36Å; V35-S38 VanDerWaalsContact O-N 3.12Å; V35-S38 PolarHBondContact O-OG 2.77Å; H36-S38 PolarHBondContact O-N 2.83Å
39Q85.3Confident88.4Confident132 Ų13263 Ų6362%0.61738%0.375SS*.G310 helixtrans-85-10.6178-58-179.81.800113.4H36 R37H36-Q39 PolarHBondContact O-N 2.79Å; R37-Q39 PolarHBondContact O-N 2.82Å; R37-Q39 VanDerWaalsContact O-N 3.14Å
40L89Confident88.5Confident32 Ų3257.7 Ų57.717%0.16836%0.36CS..SBendtrans-79.9142.5-177.2-65.2177.5000111.3R37 N44 L45 M144R37-L40 HydrophobicContact CB-CD1 4.09Å; R37-L40 WeakPolarHBondContact O-CB 3.3Å; R37-L40 PolarHBondContact O-N 3.01Å; L40-N44 HydrophobicContact CB-CB 4.3Å; L40-L45 HydrophobicContact CB-CD1 4.45Å; L40-L45 HydrophobicContact CB-CD2 4.14Å; L40-L45 HydrophobicContact CB-CG 3.81Å; L40-L45 HydrophobicContact CD1-CD2 4.2Å; L40-L45 WeakPolarHBondContact O-CD1 3.39Å; L40-M144 HydrophobicContact CD1-CG 3.73Å
41A91.6Very high88.5Confident63 Ų6360.7 Ų60.752%0.52139%0.385SS..  trans-60.6149.8170.600000111.1G43 N44 L45A41-G43 PolarHBondContact O-N 2.88Å; A41-G43 VanDerWaalsContact O-N 3.11Å; A41-N44 WeakPolarHBondContact O-CB 3.4Å; A41-N44 PolarHBondContact O-N 3.48Å; A41-L45 PolarHBondContact O-N 3.37Å
42C91.1Very high88.9Confident110 Ų11057 Ų5774%0.74337%0.371SS*.Hα-helixtrans-55.6-34.4-176.9-62.40000113.6A46C42-A46 WeakPolarHBondContact O-CB 3.37Å; C42-A46 PolarHBondContact O-N 3.2Å
43G94.4Very high89.5Confident42 Ų4262.4 Ų62.443%0.43339%0.394SS..Hα-helixtrans-61.2-50.2173.600000112A41 L45 A46 H47A41-G43 PolarHBondContact O-N 2.88Å; A41-G43 VanDerWaalsContact O-N 3.11Å; G43-L45 VanDerWaalsContact C-N 3.33Å; G43-L45 PolarHBondContact O-N 2.85Å; G43-A46 PolarHBondContact O-N 3.36Å; G43-A46 VanDerWaalsContact O-N 3.16Å; G43-H47 PolarHBondContact O-CD2 3.37Å; G43-H47 VanDerWaalsContact O-CD2 3.25Å; G43-H47 PolarHBondContact O-N 3.43Å
44N93.7Very high90.5Very high99 Ų9961.2 Ų61.253%0.52938%0.383SS..Hα-helixtrans-61.5-42.8179.1-64.3-0.1000111.5L40 A41 A46 H47 G48L40-N44 HydrophobicContact CB-CB 4.3Å; A41-N44 WeakPolarHBondContact O-CB 3.4Å; A41-N44 PolarHBondContact O-N 3.48Å; N44-A46 PolarHBondContact O-N 3.33Å; N44-H47 PolarHBondContact O-N 3.36Å; N44-G48 PolarHBondContact O-N 3Å
45L92.3Very high91.3Very high14 Ų1464.3 Ų64.37%0.07339%0.393CS..Hα-helixtrans-58-48.3173.7-78.4168.1000111.8R37 L40 A41 G43 H47 G48 F49 M63R37-L45 HydrophobicContact CB-CD2 3.84Å; R37-L45 HydrophobicContact CG-CD2 4.15Å; R37-L45 WeakPolarHBondContact O-CD2 3.46Å; L40-L45 HydrophobicContact CB-CD1 4.45Å; L40-L45 HydrophobicContact CB-CD2 4.14Å; L40-L45 HydrophobicContact CB-CG 3.81Å; L40-L45 HydrophobicContact CD1-CD2 4.2Å; L40-L45 WeakPolarHBondContact O-CD1 3.39Å; A41-L45 PolarHBondContact O-N 3.37Å; G43-L45 VanDerWaalsContact C-N 3.33Å; G43-L45 PolarHBondContact O-N 2.85Å; L45-H47 VanDerWaalsContact C-N 3.33Å; L45-H47 PolarHBondContact O-N 2.83Å; L45-G48 PolarHBondContact O-N 2.88Å; L45-G48 VanDerWaalsContact O-N 3.14Å; L45-F49 HydrophobicContact CB-CE1 3.94Å; L45-F49 HydrophobicContact CB-CZ 4.5Å; L45-F49 WeakPolarHBondContact O-CD1 3.34Å; L45-F49 WeakPolarHBondContact O-CE1 3.15Å; L45-F49 WeakPolarHBondContact O-CG 3.38Å; L45-F49 PolarHBondContact O-N 3.13Å; L45-M63 HydrophobicContact CD1-CE 3.41Å; L45-M63 VanDerWaalsContact CD1-CE 3.41Å; L45-M63 HydrophobicContact CD2-CE 3.88Å; L45-M63 HydrophobicContact CG-CE 4.27Å
46A94.1Very high92Very high44 Ų4465 Ų6536%0.36440%0.397SS..Hα-helixtrans-59.9-42.5179.800000112.3C42 G43 N44 F49 A50C42-A46 WeakPolarHBondContact O-CB 3.37Å; C42-A46 PolarHBondContact O-N 3.2Å; G43-A46 PolarHBondContact O-N 3.36Å; G43-A46 VanDerWaalsContact O-N 3.16Å; N44-A46 PolarHBondContact O-N 3.33Å; A46-F49 HydrophobicContact CB-CE2 4.41Å; A46-F49 HydrophobicContact CB-CZ 4.48Å; A46-A50 WeakPolarHBondContact O-CA 3.3Å; A46-A50 VanDerWaalsContact O-CB 3.32Å; A46-A50 WeakPolarHBondContact O-CB 3.44Å; A46-A50 PolarHBondContact O-N 2.94Å
47H95.5Very high92.7Very high161 Ų16167.5 Ų67.575%0.74541%0.408SS*.Hα-helixtrans-60.9-46.2173.6-85.7-101.8000111.7G43 N44 L45 F49 A50G43-H47 PolarHBondContact O-CD2 3.37Å; G43-H47 VanDerWaalsContact O-CD2 3.25Å; G43-H47 PolarHBondContact O-N 3.43Å; N44-H47 PolarHBondContact O-N 3.36Å; L45-H47 VanDerWaalsContact C-N 3.33Å; L45-H47 PolarHBondContact O-N 2.83Å; H47-F49 VanDerWaalsContact C-N 3.33Å; H47-F49 PolarHBondContact O-N 3.26Å; H47-A50 WeakPolarHBondContact O-CB 3.4Å; H47-A50 PolarHBondContact O-N 2.99Å
48G93.7Very high92.9Very high22 Ų2270.1 Ų70.123%0.22743%0.429CS..Hα-helixtrans-59.6-35.7-176.300000116N44 L45 Q103 M144N44-G48 PolarHBondContact O-N 3Å; L45-G48 PolarHBondContact O-N 2.88Å; L45-G48 VanDerWaalsContact O-N 3.14Å; G48-Q103 PolarHBondContact O-NE2 3.31Å; G48-M144 WeakPolarHBondContact CA-SD 3.38Å
49F94.5Very high93.3Very high25 Ų2568.2 Ų68.211%0.1142%0.416CS..THydrogen-bonded Turntrans-109.59.4178.358.8-123.1000113.9L45 A46 H47 A51 C52 K57 L60 K61L45-F49 HydrophobicContact CB-CE1 3.94Å; L45-F49 HydrophobicContact CB-CZ 4.5Å; L45-F49 WeakPolarHBondContact O-CD1 3.34Å; L45-F49 WeakPolarHBondContact O-CE1 3.15Å; L45-F49 WeakPolarHBondContact O-CG 3.38Å; L45-F49 PolarHBondContact O-N 3.13Å; A46-F49 HydrophobicContact CB-CE2 4.41Å; A46-F49 HydrophobicContact CB-CZ 4.48Å; H47-F49 VanDerWaalsContact C-N 3.33Å; H47-F49 PolarHBondContact O-N 3.26Å; F49-A51 PolarHBondContact O-N 3.16Å; F49-C52 HydrophobicContact CB-CB 4.28Å; F49-C52 VanDerWaalsContact O-CB 3.27Å; F49-C52 WeakPolarHBondContact O-CB 3.34Å; F49-C52 PolarHBondContact O-N 3.37Å; F49-K57 HydrophobicContact CB-CG 4.41Å; F49-K57 HydrophobicContact CD2-CB 4.5Å; F49-K57 HydrophobicContact CD2-CG 3.96Å; F49-K57 HydrophobicContact CG-CG 4.46Å; F49-K57 WeakPolarHBondContact O-CE 3.36Å; F49-K57 WeakPolarHBondContact O-CG 3.01Å; F49-L60 HydrophobicContact CB-CB 4.43Å; F49-L60 HydrophobicContact CB-CD1 3.57Å; F49-L60 HydrophobicContact CD1-CB 3.96Å; F49-L60 HydrophobicContact CG-CD1 4.5Å; F49-K61 HydrophobicContact CE1-CG 3.77Å; F49-K61 HydrophobicContact CE2-CG 4.35Å; F49-K61 HydrophobicContact CZ-CD 4.15Å; F49-K61 HydrophobicContact CZ-CG 3.61Å
50A95.4Very high93.7Very high58 Ų5861.9 Ų61.948%0.47939%0.386SS..THydrogen-bonded Turntrans-56.3-38.3-173.800000113A46 H47 K57A46-A50 WeakPolarHBondContact O-CA 3.3Å; A46-A50 VanDerWaalsContact O-CB 3.32Å; A46-A50 WeakPolarHBondContact O-CB 3.44Å; A46-A50 PolarHBondContact O-N 2.94Å; H47-A50 WeakPolarHBondContact O-CB 3.4Å; H47-A50 PolarHBondContact O-N 2.99Å; A50-K57 WeakPolarHBondContact O-CE 2.94Å; A50-K57 PolarHBondContact O-NZ 2.98Å
51A94.1Very high93.8Very high99 Ų9966.3 Ų66.382%0.81840%0.404SS*.THydrogen-bonded Turntrans-85.2-9.5179.900000113.9F49F49-A51 PolarHBondContact O-N 3.16Å
52C94.8Very high93.7Very high16 Ų1666 Ų6611%0.10840%0.398CS..SBendtrans-67.4153.5-179.3-66.50000111.9F49 D56 K57 Q103F49-C52 HydrophobicContact CB-CB 4.28Å; F49-C52 VanDerWaalsContact O-CB 3.27Å; F49-C52 WeakPolarHBondContact O-CB 3.34Å; F49-C52 PolarHBondContact O-N 3.37Å; C52-D56 HydrophobicContact CB-CB 3.73Å; C52-K57 HydrophobicContact CB-CG 3.89Å; C52-K57 WeakPolarHBondContact O-CD 3.35Å; C52-K57 WeakPolarHBondContact O-CE 3.12Å; C52-K57 PolarHBondContact O-NZ 3.44Å; C52-Q103 PolarHBondContact SG-NE2 3.01Å; C52-Q103 VanDerWaalsContact SG-NE2 3.38Å
53Q94.1Very high93.5Very high136 Ų13663.1 Ų63.164%0.63637%0.374SS*.  trans-64.4158.8172.3-62.8-60.5-26.900110.7E55 D56 K57Q53-E55 VanDerWaalsContact C-N 3.27Å; Q53-E55 PolarHBondContact O-N 3.11Å; Q53-D56 PolarHBondContact O-N 3.14Å; Q53-D56 VanDerWaalsContact O-N 3.15Å; Q53-K57 PolarHBondContact O-N 3.32Å
54P95.2Very high93.1Very high100 Ų10067.4 Ų67.465%0.64939%0.387SS*.Hα-helixtrans-53.7-39.2-175.8-29.236.3000114.7K57 A58P54-K57 PolarHBondContact O-N 3.47Å; P54-A58 PolarHBondContact O-N 3.01Å
55E93.9Very high92.8Very high135 Ų13566.3 Ų66.363%0.63138%0.375SS*.Hα-helixtrans-68-43.5178.7-174.9173.2-175.200112.5Q53 K57 A58 S59Q53-E55 VanDerWaalsContact C-N 3.27Å; Q53-E55 PolarHBondContact O-N 3.11Å; E55-K57 VanDerWaalsContact C-N 3.34Å; E55-K57 PolarHBondContact O-N 3.01Å; E55-A58 PolarHBondContact O-N 3.09Å; E55-S59 WeakPolarHBondContact O-CB 3.14Å; E55-S59 PolarHBondContact O-N 3.06Å; E55-S59 PolarHBondContact O-OG 2.66Å
56D95.4Very high92.8Very high14 Ų1466.4 Ų66.48%0.07538%0.376CS..Hα-helixtrans-62.4-42.3174.4-74.1-20.2000111.1C52 Q53 A58 S59 L60 H96 V101C52-D56 HydrophobicContact CB-CB 3.73Å; Q53-D56 PolarHBondContact O-N 3.14Å; Q53-D56 VanDerWaalsContact O-N 3.15Å; D56-A58 VanDerWaalsContact C-N 3.32Å; D56-A58 PolarHBondContact O-N 3.2Å; D56-S59 WeakPolarHBondContact O-CB 3.44Å; D56-S59 PolarHBondContact O-N 3.2Å; D56-L60 WeakPolarHBondContact O-CB 3.28Å; D56-L60 VanDerWaalsContact O-CG 3.3Å; D56-L60 WeakPolarHBondContact O-CG 3.34Å; D56-L60 PolarHBondContact O-N 3.46Å; D56-H96 IonicContact OD1-CD2 2.75Å; D56-H96 IonicContact OD1-CE1 3.15Å; D56-H96 IonicContact OD1-NE2 2.71Å; D56-H96 PolarHBondContact OD1-NE2 3.37Å; D56-H96 IonicContact OD2-CE1 3.26Å; D56-H96 IonicContact OD2-NE2 2.73Å; D56-H96 PolarHBondContact OD2-NE2 2.82Å; D56-V101 HydrophobicContact CB-CG1 4.06Å; D56-V101 HydrophobicContact CB-CG2 4.3Å
57K95.2Very high92.9Very high66 Ų6664.3 Ų64.329%0.28736%0.358SS..Hα-helixtrans-59-44.9174.4-74.3176.2172158.80111.3F49 A50 C52 Q53 P54 E55 K61F49-K57 HydrophobicContact CB-CG 4.41Å; F49-K57 HydrophobicContact CD2-CB 4.5Å; F49-K57 HydrophobicContact CD2-CG 3.96Å; F49-K57 HydrophobicContact CG-CG 4.46Å; F49-K57 WeakPolarHBondContact O-CE 3.36Å; F49-K57 WeakPolarHBondContact O-CG 3.01Å; A50-K57 WeakPolarHBondContact O-CE 2.94Å; A50-K57 PolarHBondContact O-NZ 2.98Å; C52-K57 HydrophobicContact CB-CG 3.89Å; C52-K57 WeakPolarHBondContact O-CD 3.35Å; C52-K57 WeakPolarHBondContact O-CE 3.12Å; C52-K57 PolarHBondContact O-NZ 3.44Å; Q53-K57 PolarHBondContact O-N 3.32Å; P54-K57 PolarHBondContact O-N 3.47Å; E55-K57 VanDerWaalsContact C-N 3.34Å; E55-K57 PolarHBondContact O-N 3.01Å; K57-K61 VanDerWaalsContact O-CB 3.3Å; K57-K61 WeakPolarHBondContact O-CB 3.43Å; K57-K61 WeakPolarHBondContact O-CE 3.36Å; K57-K61 WeakPolarHBondContact O-CG 3.29Å; K57-K61 PolarHBondContact O-N 3.13Å
58A93.4Very high93Very high54 Ų5456.7 Ų56.745%0.44632%0.323SS..Hα-helixtrans-62.5-44.5176.700000111.4P54 E55 D56 K61 S62P54-A58 PolarHBondContact O-N 3.01Å; E55-A58 PolarHBondContact O-N 3.09Å; D56-A58 VanDerWaalsContact C-N 3.32Å; D56-A58 PolarHBondContact O-N 3.2Å; A58-K61 PolarHBondContact O-N 2.96Å; A58-S62 PolarHBondContact O-N 2.72Å; A58-S62 VanDerWaalsContact O-N 3.11Å
59S92.6Very high93.2Very high10 Ų1055.6 Ų55.67%0.0731%0.312CS..Hα-helixtrans-60.3-44.3177-67.50000113E55 D56 S62 R65E55-S59 WeakPolarHBondContact O-CB 3.14Å; E55-S59 PolarHBondContact O-N 3.06Å; E55-S59 PolarHBondContact O-OG 2.66Å; D56-S59 WeakPolarHBondContact O-CB 3.44Å; D56-S59 PolarHBondContact O-N 3.2Å; S59-S62 PolarHBondContact O-OG 2.95Å; S59-R65 WeakPolarHBondContact OG-CD 3.43Å; S59-R65 PolarHBondContact OG-NH1 3.09Å
60L93.2Very high93.4Very high0 Ų054.4 Ų54.40%031%0.307CS..Hα-helixtrans-72.2-39.6179.9-68.2175.6000111.6R37 F49 D56 S62 M63 N67 V101R37-L60 PolarHBondContact NE-O 2.92Å; R37-L60 PolarHBondContact NH2-O 3.49Å; F49-L60 HydrophobicContact CB-CB 4.43Å; F49-L60 HydrophobicContact CB-CD1 3.57Å; F49-L60 HydrophobicContact CD1-CB 3.96Å; F49-L60 HydrophobicContact CG-CD1 4.5Å; D56-L60 WeakPolarHBondContact O-CB 3.28Å; D56-L60 VanDerWaalsContact O-CG 3.3Å; D56-L60 WeakPolarHBondContact O-CG 3.34Å; D56-L60 PolarHBondContact O-N 3.46Å; L60-S62 VanDerWaalsContact C-N 3.3Å; L60-S62 PolarHBondContact O-N 3.14Å; L60-M63 PolarHBondContact O-N 2.65Å; L60-N67 HydrophobicContact CD2-CB 3.59Å; L60-V101 HydrophobicContact CD1-CG1 4.15Å; L60-V101 HydrophobicContact CD2-CB 4.08Å; L60-V101 HydrophobicContact CD2-CG1 4.33Å; L60-V101 HydrophobicContact CD2-CG2 4.22Å; L60-V101 HydrophobicContact CG-CB 4.4Å; L60-V101 HydrophobicContact CG-CG1 4.31Å; L60-V101 HydrophobicContact CG-CG2 4.22Å
61K91.9Very high93.6Very high125 Ų12551.7 Ų51.754%0.54328%0.284SS..Hα-helixtrans-63.5-30.9176.1-77.5-178.2-63176.50113.7F49 K57 A58 M63F49-K61 HydrophobicContact CE1-CG 3.77Å; F49-K61 HydrophobicContact CE2-CG 4.35Å; F49-K61 HydrophobicContact CZ-CD 4.15Å; F49-K61 HydrophobicContact CZ-CG 3.61Å; K57-K61 VanDerWaalsContact O-CB 3.3Å; K57-K61 WeakPolarHBondContact O-CB 3.43Å; K57-K61 WeakPolarHBondContact O-CE 3.36Å; K57-K61 WeakPolarHBondContact O-CG 3.29Å; K57-K61 PolarHBondContact O-N 3.13Å; A58-K61 PolarHBondContact O-N 2.96Å; K61-M63 PolarHBondContact O-N 3.34Å
62S88.5Confident93.8Very high55 Ų5547.8 Ų47.839%0.38525%0.25SC..THydrogen-bonded Turntrans-69-16.8-178.873.50000113.1A58 S59 L60 L64A58-S62 PolarHBondContact O-N 2.72Å; A58-S62 VanDerWaalsContact O-N 3.11Å; S59-S62 PolarHBondContact O-OG 2.95Å; L60-S62 VanDerWaalsContact C-N 3.3Å; L60-S62 PolarHBondContact O-N 3.14Å; S62-L64 WeakPolarHBondContact O-CG 3.26Å; S62-L64 PolarHBondContact O-N 3.47Å; S62-L64 VanDerWaalsContact O-N 3.14Å; S62-L64 PolarHBondContact OG-N 3.12Å
63M87.9Confident94Very high51 Ų5147 Ų4725%0.25125%0.245SC..THydrogen-bonded Turntrans59.814.7-174.3-51.8-56.2167.300114.6V35 R37 L45 L60 K61V35-M63 WeakPolarHBondContact CG1-O 3.34Å; V35-M63 HydrophobicContact CG2-CB 3.78Å; V35-M63 HydrophobicContact CG2-CG 4.49Å; V35-M63 VanDerWaalsContact CG2-O 3.24Å; V35-M63 WeakPolarHBondContact CG2-O 3.36Å; V35-M63 HydrophobicContact CG2-SD 4.08Å; R37-M63 HydrophobicContact CG-SD 3.76Å; L45-M63 HydrophobicContact CD1-CE 3.41Å; L45-M63 VanDerWaalsContact CD1-CE 3.41Å; L45-M63 HydrophobicContact CD2-CE 3.88Å; L45-M63 HydrophobicContact CG-CE 4.27Å; L60-M63 PolarHBondContact O-N 2.65Å; K61-M63 PolarHBondContact O-N 3.34Å
64L85.1Confident94.2Very high132 Ų13244.9 Ų44.969%0.69123%0.232SC*.  trans-101.2-33.7-178-63.5174.2000113S62S62-L64 WeakPolarHBondContact O-CG 3.26Å; S62-L64 PolarHBondContact O-N 3.47Å; S62-L64 VanDerWaalsContact O-N 3.14Å; S62-L64 PolarHBondContact OG-N 3.12Å
65R89Confident94.3Very high76 Ų7642.1 Ų42.129%0.28721%0.212SC..SBendtrans-90.9146.7-174.3-69-173.9173.6-165.6-3.3111.9R37 S59 N99R37-R65 VanDerWaalsContact CZ-O 3.26Å; R37-R65 PolarHBondContact NH1-O 3.26Å; R37-R65 PolarHBondContact NH2-O 2.89Å; S59-R65 WeakPolarHBondContact OG-CD 3.43Å; S59-R65 PolarHBondContact OG-NH1 3.09Å; R65-N99 WeakPolarHBondContact CB-O 3.47Å; R65-N99 VanDerWaalsContact CD-O 3.25Å; R65-N99 WeakPolarHBondContact CD-O 3.28Å; R65-N99 VanDerWaalsContact CG-O 3.29Å; R65-N99 WeakPolarHBondContact CG-O 3.49Å; R65-N99 PolarHBondContact NH2-OD1 2.8Å
66N92.4Very high94.4Very high16 Ų1640.8 Ų40.89%0.08621%0.209CC..  trans-66.6141.7174.4-67.9-33.5000111.1I68 A100 V101 D146 T269 N271N66-I68 HydrophobicContact CB-CD1 4.24Å; N66-A100 HydrophobicContact CB-CB 4.11Å; N66-V101 PolarHBondContact O-N 2.89Å; N66-D146 WeakPolarHBondContact CA-OD2 3.48Å; N66-D146 HydrophobicContact CB-CB 4.38Å; N66-T269 PolarHBondContact ND2-OG1 2.96Å; N66-T269 PolarHBondContact OD1-OG1 3.39Å; N66-N271 WeakPolarHBondContact OD1-CB 3.24Å; N66-N271 PolarHBondContact OD1-ND2 2.86Å
67N95.7Very high94.4Very high0 Ų046.5 Ų46.50%024%0.237CC..EExtended strand (participates in β ladder)trans-112.4121.1165.7-168.220.8000109.6L60 V101 Q103 M144 F145 D146L60-N67 HydrophobicContact CD2-CB 3.59Å; N67-V101 CarbonylContact C-O 3.6Å; N67-V101 WeakPolarHBondContact CA-O 3.22Å; N67-V101 PolarHBondContact OD1-O 3.22Å; N67-Q103 PolarHBondContact ND2-OE1 3.25Å; N67-Q103 PolarHBondContact OD1-OE1 3.5Å; N67-M144 WeakPolarHBondContact CB-O 3.41Å; N67-M144 PolarHBondContact ND2-O 3.15Å; N67-M144 VanDerWaalsContact ND2-O 3.1Å; N67-F145 CarbonylContact O-C 3.54Å; N67-F145 VanDerWaalsContact O-CA 3.26Å; N67-F145 WeakPolarHBondContact O-CA 3.4Å; N67-D146 PolarHBondContact N-OD2 2.92Å; N67-D146 PolarHBondContact O-N 2.94Å
68I97.5Very high94.4Very high0 Ų043.6 Ų43.60%022%0.224CC..EExtended strand (participates in β ladder)trans-105.5124.4-175-56.6-54.8000109.5N66 L95 V101 G102 Q103 G147 L149 V265 T266 T269N66-I68 HydrophobicContact CB-CD1 4.24Å; I68-L95 HydrophobicContact CB-CD1 3.88Å; I68-L95 HydrophobicContact CB-CD2 4.15Å; I68-L95 HydrophobicContact CG1-CD1 4.28Å; I68-L95 HydrophobicContact CG1-CD2 3.66Å; I68-L95 HydrophobicContact CG2-CD1 4.36Å; I68-V101 PolarHBondContact N-O 3.31Å; I68-G102 WeakPolarHBondContact O-CA 3.29Å; I68-Q103 PolarHBondContact O-N 2.84Å; I68-G147 WeakPolarHBondContact CA-O 3.38Å; I68-L149 HydrophobicContact CG2-CD1 4.06Å; I68-L149 HydrophobicContact CG2-CG 4.03Å; I68-V265 HydrophobicContact CD1-CG1 4.14Å; I68-V265 HydrophobicContact CG1-CG1 4.17Å; I68-V265 HydrophobicContact CG2-CG1 3.78Å; I68-T266 HydrophobicContact CD1-CG2 4.14Å; I68-T266 HydrophobicContact CG1-CG2 3.92Å; I68-T269 HydrophobicContact CD1-CG2 4.29Å
69A98.5Very high94.5Very high0 Ų043 Ų430%022%0.217CC..EExtended strand (participates in β ladder)trans-70137.4171.900000110.4Q103 A105 L140 F145 G147 A148 L149A69-Q103 CarbonylContact C-O 3.54Å; A69-A105 HydrophobicContact CB-CB 3.68Å; A69-L140 HydrophobicContact CB-CD2 3.59Å; A69-F145 HydrophobicContact CB-CB 3.98Å; A69-F145 HydrophobicContact CB-CD1 3.79Å; A69-F145 HydrophobicContact CB-CD2 3.78Å; A69-F145 HydrophobicContact CB-CE1 4.2Å; A69-F145 HydrophobicContact CB-CE2 4.18Å; A69-F145 HydrophobicContact CB-CG 3.57Å; A69-F145 HydrophobicContact CB-CZ 4.39Å; A69-G147 PolarHBondContact N-O 3.21Å; A69-A148 HydrophobicContact CB-CB 3.94Å; A69-A148 CarbonylContact O-C 3.56Å; A69-A148 WeakPolarHBondContact O-CA 3.41Å; A69-L149 PolarHBondContact O-N 3.25Å
70I98.8Very high94.6Very high0 Ų043 Ų430%022%0.217CC..EExtended strand (participates in β ladder)trans-111.6112.3165.5-52169.3000106.8P88 I91 Q103 V104 A105 L151I70-P88 HydrophobicContact CD1-CB 4.28Å; I70-I91 HydrophobicContact CD1-CB 4.13Å; I70-I91 HydrophobicContact CD1-CD1 4.48Å; I70-I91 HydrophobicContact CD1-CG2 3.58Å; I70-I91 HydrophobicContact CG1-CG2 4Å; I70-I91 HydrophobicContact CG2-CD1 4.34Å; I70-Q103 PolarHBondContact N-O 2.95Å; I70-V104 HydrophobicContact CB-CG2 4.31Å; I70-V104 WeakPolarHBondContact O-CA 3.49Å; I70-A105 PolarHBondContact O-N 3.15Å; I70-L151 HydrophobicContact CG2-CD1 3.62Å; I70-L151 HydrophobicContact CG2-CG 4.02Å
71I98.8Very high94.8Very high0 Ų043 Ų430%022%0.217CC..EExtended strand (participates in β ladder)trans-100.3114.1171.4-58.3-64.1000107.1A105 V108 A136 L140 L149 F150 L151 L161I71-A105 HydrophobicContact CD1-CB 3.77Å; I71-V108 HydrophobicContact CG2-CG1 3.73Å; I71-A136 HydrophobicContact CG2-CB 3.96Å; I71-L140 HydrophobicContact CD1-CD2 4.2Å; I71-L140 HydrophobicContact CD1-CG 4.13Å; I71-L140 HydrophobicContact CG1-CD2 4.23Å; I71-L140 HydrophobicContact CG1-CG 4.33Å; I71-L149 PolarHBondContact N-O 3.28Å; I71-F150 HydrophobicContact CB-CD1 4Å; I71-F150 HydrophobicContact CB-CE1 4.22Å; I71-F150 HydrophobicContact CG1-CD1 4.3Å; I71-F150 HydrophobicContact CG1-CE1 4.02Å; I71-F150 HydrophobicContact CG2-CD1 4.33Å; I71-L151 PolarHBondContact O-N 3.41Å; I71-L161 HydrophobicContact CG2-CD2 3.7Å
72T98.8Very high95.1Very high17 Ų1739.3 Ų39.310%0.10420%0.202CC..EExtended strand (participates in β ladder)trans-114.4135.7-173.4-176.50000112Y74 V104 G106 G107 V108T72-Y74 WeakPolarHBondContact OG1-CB 3.33Å; T72-Y74 PolarHBondContact OG1-N 3.18Å; T72-Y74 VanDerWaalsContact OG1-N 3.1Å; T72-V104 HydrophobicContact CG2-CG1 4.13Å; T72-G106 PolarHBondContact N-O 2.79Å; T72-G107 CarbonylContact O-C 3.51Å; T72-G107 VanDerWaalsContact O-CA 3.32Å; T72-G107 WeakPolarHBondContact O-CA 3.39Å; T72-V108 PolarHBondContact O-N 3.03Å
73S98.3Very high95.5Very high0 Ų037.4 Ų37.40%019%0.188CC..  trans-102.233.2165.663.80000111.9N75 H81 V108 A110 L151 G152 I157S73-N75 PolarHBondContact O-N 3.5Å; S73-H81 VanDerWaalsContact O-CB 3.29Å; S73-H81 WeakPolarHBondContact O-CB 3.35Å; S73-H81 PolarHBondContact O-CD2 3.35Å; S73-H81 PolarHBondContact OG-CD2 3Å; S73-H81 PolarHBondContact OG-NE2 3.24Å; S73-V108 VanDerWaalsContact CB-CG2 3.47Å; S73-A110 VanDerWaalsContact O-CB 3.26Å; S73-A110 WeakPolarHBondContact O-CB 3.32Å; S73-L151 PolarHBondContact N-O 3.28Å; S73-L151 PolarHBondContact OG-O 3.08Å; S73-G152 VanDerWaalsContact OG-CA 3.27Å; S73-G152 WeakPolarHBondContact OG-CA 3.42Å; S73-I157 WeakPolarHBondContact OG-CG2 3.17Å
74Y98.3Very high96Very high91 Ų9135 Ų3536%0.35718%0.177SC..  trans-52.1131.8173.7168.6-111.7000111.5T72 Q82 E85T72-Y74 WeakPolarHBondContact OG1-CB 3.33Å; T72-Y74 PolarHBondContact OG1-N 3.18Å; T72-Y74 VanDerWaalsContact OG1-N 3.1Å; Y74-Q82 WeakPolarHBondContact CE2-O 3.44Å; Y74-E85 HydrophobicContact CD2-CB 3.99Å; Y74-E85 HydrophobicContact CE2-CB 3.47Å; Y74-E85 VanDerWaalsContact CE2-CB 3.47Å; Y74-E85 HydrophobicContact CE2-CG 3.95Å
75N97.5Very high96.6Very high43 Ų4332.8 Ų32.823%0.2316%0.163CC..  trans-154.8117.7173.7-176.3-41.1000108.6S73 M77 L78 H81 Q82 A110S73-N75 PolarHBondContact O-N 3.5Å; N75-M77 VanDerWaalsContact C-N 3.28Å; N75-M77 PolarHBondContact O-N 3.03Å; N75-M77 WeakPolarHBondContact OD1-CB 3.45Å; N75-M77 PolarHBondContact OD1-N 3.1Å; N75-L78 HydrophobicContact CB-CB 4.3Å; N75-L78 HydrophobicContact CB-CD1 4.19Å; N75-L78 HydrophobicContact CB-CG 4.12Å; N75-L78 PolarHBondContact O-N 3.37Å; N75-H81 HydrophobicContact CB-CB 4.34Å; N75-Q82 WeakPolarHBondContact O-CA 3.44Å; N75-Q82 PolarHBondContact O-N 3.35Å; N75-Q82 VanDerWaalsContact O-N 3.16Å; N75-A110 HydrophobicContact CB-CB 3.86Å
76D95.9Very high97Very high107 Ų10733.9 Ų33.957%0.57217%0.171SC*.THydrogen-bonded Turntrans-61.9-31.5-175.6-171.240.2000113.7
77M95.1Very high97.2Very high134 Ų13433.4 Ų33.466%0.6617%0.168SC*.THydrogen-bonded Turntrans-73.8-27.8179.5176.4-175.648.600112.5N75N75-M77 VanDerWaalsContact C-N 3.28Å; N75-M77 PolarHBondContact O-N 3.03Å; N75-M77 WeakPolarHBondContact OD1-CB 3.45Å; N75-M77 PolarHBondContact OD1-N 3.1Å
78L95.6Very high97.4Very high5 Ų534.1 Ų34.13%0.02617%0.173CC..  trans-96.7112.5-169.9-59-172.2000110.1N75 A80 H81 Q82 A110 C112 V115N75-L78 HydrophobicContact CB-CB 4.3Å; N75-L78 HydrophobicContact CB-CD1 4.19Å; N75-L78 HydrophobicContact CB-CG 4.12Å; N75-L78 PolarHBondContact O-N 3.37Å; L78-A80 PolarHBondContact O-N 3.45Å; L78-H81 HydrophobicContact CB-CB 4.23Å; L78-H81 CarbonylContact O-C 3.54Å; L78-H81 PolarHBondContact O-N 3.19Å; L78-Q82 PolarHBondContact O-N 3.18Å; L78-A110 HydrophobicContact CD1-CB 3.76Å; L78-A110 WeakPolarHBondContact CD1-O 3.21Å; L78-C112 HydrophobicContact CD1-CB 3.85Å; L78-C112 HydrophobicContact CD2-CB 3.41Å; L78-C112 VanDerWaalsContact CD2-CB 3.41Å; L78-C112 HydrophobicContact CG-CB 4.16Å; L78-V115 HydrophobicContact CD2-CG2 3.85Å
79S95.1Very high97.4Very high41 Ų4140 Ų4029%0.28720%0.2SC..THydrogen-bonded Turntrans-48.2-40.1-17768.30000113.5H81 P83 G219S79-H81 VanDerWaalsContact C-N 3.27Å; S79-H81 PolarHBondContact O-N 3.46Å; S79-P83 WeakPolarHBondContact O-CD 3.33Å; S79-G219 CarbonylContact C-O 3.1Å; S79-G219 PolarHBondContact O-N 3.39Å; S79-G219 PolarHBondContact OG-O 2.78Å
80A95.6Very high97.4Very high10 Ų1041.9 Ų41.98%0.08321%0.209CC..THydrogen-bonded Turntrans-73.5-13.5-178.800000114.7L78 V153 S178 G219 T220L78-A80 PolarHBondContact O-N 3.45Å; A80-V153 HydrophobicContact CB-CG2 3.9Å; A80-V153 VanDerWaalsContact O-CG2 3.3Å; A80-V153 WeakPolarHBondContact O-CG2 3.35Å; A80-S178 PolarHBondContact O-OG 2.93Å; A80-G219 WeakPolarHBondContact CA-O 3.48Å; A80-G219 PolarHBondContact N-O 3.21Å; A80-T220 HydrophobicContact CB-CG2 3.88Å
81H97.2Very high97.3Very high1 Ų141.9 Ų41.91%0.00521%0.209CC..THydrogen-bonded Turntrans-124.7-18.4-173.3-69.676.9000113.8S73 N75 L78 S79 P83 Y84 V153 C154 I157S73-H81 VanDerWaalsContact O-CB 3.29Å; S73-H81 WeakPolarHBondContact O-CB 3.35Å; S73-H81 PolarHBondContact O-CD2 3.35Å; S73-H81 PolarHBondContact OG-CD2 3Å; S73-H81 PolarHBondContact OG-NE2 3.24Å; N75-H81 HydrophobicContact CB-CB 4.34Å; L78-H81 HydrophobicContact CB-CB 4.23Å; L78-H81 CarbonylContact O-C 3.54Å; L78-H81 PolarHBondContact O-N 3.19Å; S79-H81 VanDerWaalsContact C-N 3.27Å; S79-H81 PolarHBondContact O-N 3.46Å; H81-P83 VanDerWaalsContact C-N 3.27Å; H81-Y84 HydrophobicContact CB-CD2 4.24Å; H81-Y84 AromaticContact CD2-CD2 3.76Å; H81-Y84 AromaticContact CD2-CE2 3.55Å; H81-Y84 WeakPolarHBondContact O-CB 3.37Å; H81-Y84 PolarHBondContact O-N 3.31Å; H81-Y84 VanDerWaalsContact O-N 3.13Å; H81-V153 PolarHBondContact NE2-N 3.31Å; H81-V153 VanDerWaalsContact NE2-N 3.17Å; H81-C154 PolarHBondContact CE1-N 3.27Å; H81-C154 VanDerWaalsContact CE1-N 3.32Å; H81-I157 VanDerWaalsContact CE1-CD1 3.4Å; H81-I157 WeakPolarHBondContact CE1-CD1 3.19Å; H81-I157 VanDerWaalsContact NE2-CD1 3.26Å; H81-I157 WeakPolarHBondContact NE2-CD1 3.48Å
82Q97.3Very high97.3Very high47 Ų4746.7 Ų46.722%0.2223%0.228CC..G310 helixtrans-52.7-40.1170.7-173.9-78.3-32.700112.2Y74 N75 L78 Y84 E85Y74-Q82 WeakPolarHBondContact CE2-O 3.44Å; N75-Q82 WeakPolarHBondContact O-CA 3.44Å; N75-Q82 PolarHBondContact O-N 3.35Å; N75-Q82 VanDerWaalsContact O-N 3.16Å; L78-Q82 PolarHBondContact O-N 3.18Å; Q82-Y84 PolarHBondContact O-N 3.06Å; Q82-E85 PolarHBondContact NE2-OE2 2.88Å; Q82-E85 PolarHBondContact O-N 2.93Å; Q82-E85 VanDerWaalsContact O-N 3.13Å
83P97.2Very high97.3Very high15 Ų1552.4 Ų52.410%0.09725%0.251CS..G310 helixtrans-55.7-24.9178-29.736.6000114.9S79 H81 E85 Y87 P218 P249S79-P83 WeakPolarHBondContact O-CD 3.33Å; H81-P83 VanDerWaalsContact C-N 3.27Å; P83-E85 PolarHBondContact O-N 3.45Å; P83-E85 VanDerWaalsContact O-N 3.12Å; P83-Y87 HydrophobicContact CB-CE1 4.25Å; P83-Y87 WeakPolarHBondContact O-CD1 3.48Å; P83-Y87 WeakPolarHBondContact O-CE1 3.39Å; P83-P218 HydrophobicContact CG-CB 3.94Å; P83-P249 HydrophobicContact CB-CB 4.11Å; P83-P249 HydrophobicContact CG-CB 3.9Å; P83-P249 HydrophobicContact CG-CG 4.19Å
84Y98.2Very high97.3Very high1 Ų152.4 Ų52.40%0.00425%0.251CS..G310 helixtrans-69.2-5.2-178.9-66.7-51.7000114.8H81 Q82 H86 Y87 P88 L151 G152 V176 S178H81-Y84 HydrophobicContact CB-CD2 4.24Å; H81-Y84 AromaticContact CD2-CD2 3.76Å; H81-Y84 AromaticContact CD2-CE2 3.55Å; H81-Y84 WeakPolarHBondContact O-CB 3.37Å; H81-Y84 PolarHBondContact O-N 3.31Å; H81-Y84 VanDerWaalsContact O-N 3.13Å; Q82-Y84 PolarHBondContact O-N 3.06Å; Y84-H86 VanDerWaalsContact C-N 3.28Å; Y84-H86 PolarHBondContact O-N 2.98Å; Y84-Y87 HydrophobicContact CD1-CD1 4.41Å; Y84-Y87 AromaticContact CD1-CD2 3.41Å; Y84-Y87 HydrophobicContact CD1-CD2 3.41Å; Y84-Y87 VanDerWaalsContact CD1-CD2 3.41Å; Y84-Y87 AromaticContact CD1-CE2 3.61Å; Y84-Y87 HydrophobicContact CD1-CE2 3.61Å; Y84-Y87 AromaticContact CD1-CG 3.82Å; Y84-Y87 HydrophobicContact CD1-CG 3.82Å; Y84-Y87 AromaticContact CE1-CD2 3.7Å; Y84-Y87 HydrophobicContact CE1-CD2 3.7Å; Y84-Y87 AromaticContact CE1-CE2 3.57Å; Y84-Y87 HydrophobicContact CE1-CE2 3.57Å; Y84-Y87 PolarHBondContact O-N 3.47Å; Y84-P88 VanDerWaalsContact O-CD 3.25Å; Y84-P88 WeakPolarHBondContact O-CD 3.43Å; Y84-L151 HydrophobicContact CD1-CB 3.71Å; Y84-L151 HydrophobicContact CD1-CD1 4.16Å; Y84-L151 HydrophobicContact CD1-CG 4.45Å; Y84-L151 HydrophobicContact CD2-CB 4.39Å; Y84-L151 HydrophobicContact CE1-CB 3.64Å; Y84-L151 HydrophobicContact CE2-CB 4.34Å; Y84-L151 HydrophobicContact CG-CB 4.09Å; Y84-G152 WeakPolarHBondContact OH-CA 3.39Å; Y84-G152 PolarHBondContact OH-N 3.19Å; Y84-V176 WeakPolarHBondContact CE1-O 3.48Å; Y84-V176 PolarHBondContact OH-O 2.96Å; Y84-S178 PolarHBondContact OH-N 3.35Å
85E97.6Very high97.3Very high85 Ų8548.1 Ų48.140%0.39723%0.234SC..G310 helixtrans-50.2-47.9177.7-168.5174.1167.600112.4Y74 Q82 P83Y74-E85 HydrophobicContact CD2-CB 3.99Å; Y74-E85 HydrophobicContact CE2-CB 3.47Å; Y74-E85 VanDerWaalsContact CE2-CB 3.47Å; Y74-E85 HydrophobicContact CE2-CG 3.95Å; Q82-E85 PolarHBondContact NE2-OE2 2.88Å; Q82-E85 PolarHBondContact O-N 2.93Å; Q82-E85 VanDerWaalsContact O-N 3.13Å; P83-E85 PolarHBondContact O-N 3.45Å; P83-E85 VanDerWaalsContact O-N 3.12Å
86H96.9Very high97.2Very high98 Ų9850 Ų5045%0.45424%0.241SC..SBendtrans-99-8.4-172.4-53.3-56.1000113.6Y84 E89 I90Y84-H86 VanDerWaalsContact C-N 3.28Å; Y84-H86 PolarHBondContact O-N 2.98Å; H86-E89 WeakPolarHBondContact O-CB 3.48Å; H86-E89 PolarHBondContact O-N 3.21Å; H86-I90 PolarHBondContact O-N 3.2Å
87Y98.2Very high97.3Very high6 Ų650.1 Ų50.12%0.02424%0.239CC..Hα-helixtrans-60.1-40.6-176.1-80.338.8000112.8P83 Y84 E89 I90 I91 V176 R254 T258P83-Y87 HydrophobicContact CB-CE1 4.25Å; P83-Y87 WeakPolarHBondContact O-CD1 3.48Å; P83-Y87 WeakPolarHBondContact O-CE1 3.39Å; Y84-Y87 HydrophobicContact CD1-CD1 4.41Å; Y84-Y87 AromaticContact CD1-CD2 3.41Å; Y84-Y87 HydrophobicContact CD1-CD2 3.41Å; Y84-Y87 VanDerWaalsContact CD1-CD2 3.41Å; Y84-Y87 AromaticContact CD1-CE2 3.61Å; Y84-Y87 HydrophobicContact CD1-CE2 3.61Å; Y84-Y87 AromaticContact CD1-CG 3.82Å; Y84-Y87 HydrophobicContact CD1-CG 3.82Å; Y84-Y87 AromaticContact CE1-CD2 3.7Å; Y84-Y87 HydrophobicContact CE1-CD2 3.7Å; Y84-Y87 AromaticContact CE1-CE2 3.57Å; Y84-Y87 HydrophobicContact CE1-CE2 3.57Å; Y84-Y87 PolarHBondContact O-N 3.47Å; Y87-E89 PolarHBondContact O-N 3.44Å; Y87-E89 VanDerWaalsContact O-N 3.13Å; Y87-I90 PolarHBondContact O-N 3.38Å; Y87-I91 WeakPolarHBondContact O-CB 3.07Å; Y87-I91 WeakPolarHBondContact O-CD1 3.47Å; Y87-I91 WeakPolarHBondContact O-CG1 3.49Å; Y87-I91 PolarHBondContact O-N 3.21Å; Y87-V176 HydrophobicContact CD2-CG1 4.25Å; Y87-V176 HydrophobicContact CE2-CG1 4.21Å; Y87-R254 VanDerWaalsContact OH-CD 3.24Å; Y87-R254 WeakPolarHBondContact OH-CD 3.44Å; Y87-R254 VanDerWaalsContact OH-CG 3.26Å; Y87-R254 WeakPolarHBondContact OH-CG 3.47Å; Y87-T258 HydrophobicContact CD2-CG2 3.76Å; Y87-T258 HydrophobicContact CE2-CG2 4.3Å; Y87-T258 HydrophobicContact CG-CG2 4.14Å
88P98.3Very high97.2Very high16 Ų1645.5 Ų45.510%0.10422%0.222CC..Hα-helixtrans-57.7-26175.9-27.536000114.6I70 Y84 R92 V104I70-P88 HydrophobicContact CD1-CB 4.28Å; Y84-P88 VanDerWaalsContact O-CD 3.25Å; Y84-P88 WeakPolarHBondContact O-CD 3.43Å; P88-R92 WeakPolarHBondContact O-CB 3.48Å; P88-R92 VanDerWaalsContact O-CG 3.24Å; P88-R92 WeakPolarHBondContact O-CG 3.31Å; P88-R92 PolarHBondContact O-N 2.92Å; P88-R92 VanDerWaalsContact O-N 3.1Å; P88-R92 PolarHBondContact O-NE 3.03Å; P88-R92 VanDerWaalsContact O-NE 3.11Å; P88-V104 HydrophobicContact CB-CG2 4.03Å; P88-V104 HydrophobicContact CG-CG2 4.15Å
89E97.7Very high97.1Very high123 Ų12349.8 Ų49.858%0.57525%0.245SC*.Hα-helixtrans-76.4-48.4176.2-61.8-176.5167.900111.3H86 Y87 I91 R92 K93H86-E89 WeakPolarHBondContact O-CB 3.48Å; H86-E89 PolarHBondContact O-N 3.21Å; Y87-E89 PolarHBondContact O-N 3.44Å; Y87-E89 VanDerWaalsContact O-N 3.13Å; E89-I91 VanDerWaalsContact C-N 3.28Å; E89-I91 PolarHBondContact O-N 2.69Å; E89-R92 PolarHBondContact O-N 3.1Å; E89-K93 WeakPolarHBondContact O-CB 3.39Å; E89-K93 PolarHBondContact O-N 3.22Å
90I98.3Very high97.1Very high39 Ų3947.9 Ų47.920%0.223%0.232CC..Hα-helixtrans-56.6-46.1174.8-60171.9000110.3H86 Y87 K93 A94 D255 T258 A259H86-I90 PolarHBondContact O-N 3.2Å; Y87-I90 PolarHBondContact O-N 3.38Å; I90-K93 PolarHBondContact O-N 3.18Å; I90-A94 WeakPolarHBondContact O-CB 3.5Å; I90-A94 PolarHBondContact O-N 3.29Å; I90-D255 HydrophobicContact CD1-CB 4.33Å; I90-D255 WeakPolarHBondContact CD1-OD1 3.33Å; I90-T258 HydrophobicContact CB-CG2 4.42Å; I90-T258 HydrophobicContact CG2-CG2 4.07Å; I90-A259 HydrophobicContact CG2-CB 4.15Å
91I98.7Very high97.2Very high0 Ų047.5 Ų47.50%023%0.228CC..Hα-helixtrans-62.6-50.3179.4-70.3165.8000110.8I70 Y87 E89 K93 A94 L95 L149 L151 T258 A262I70-I91 HydrophobicContact CD1-CB 4.13Å; I70-I91 HydrophobicContact CD1-CD1 4.48Å; I70-I91 HydrophobicContact CD1-CG2 3.58Å; I70-I91 HydrophobicContact CG1-CG2 4Å; I70-I91 HydrophobicContact CG2-CD1 4.34Å; Y87-I91 WeakPolarHBondContact O-CB 3.07Å; Y87-I91 WeakPolarHBondContact O-CD1 3.47Å; Y87-I91 WeakPolarHBondContact O-CG1 3.49Å; Y87-I91 PolarHBondContact O-N 3.21Å; E89-I91 VanDerWaalsContact C-N 3.28Å; E89-I91 PolarHBondContact O-N 2.69Å; I91-K93 VanDerWaalsContact C-N 3.32Å; I91-K93 PolarHBondContact O-N 2.9Å; I91-A94 PolarHBondContact O-N 3.4Å; I91-L95 HydrophobicContact CG2-CD1 3.67Å; I91-L95 HydrophobicContact CG2-CG 4.26Å; I91-L95 VanDerWaalsContact O-CG 3.28Å; I91-L95 WeakPolarHBondContact O-CG 3.23Å; I91-L95 PolarHBondContact O-N 3.03Å; I91-L149 HydrophobicContact CB-CD1 4.43Å; I91-L149 HydrophobicContact CD1-CD1 4.08Å; I91-L149 HydrophobicContact CG1-CD1 4.18Å; I91-L149 HydrophobicContact CG2-CD1 3.4Å; I91-L151 HydrophobicContact CD1-CD1 4.06Å; I91-L151 HydrophobicContact CD1-CD2 3.88Å; I91-T258 HydrophobicContact CD1-CG2 4.29Å; I91-T258 HydrophobicContact CG1-CG2 3.82Å; I91-A262 HydrophobicContact CB-CB 4.39Å; I91-A262 HydrophobicContact CG1-CB 4.44Å; I91-A262 HydrophobicContact CG2-CB 3.94Å
92R98.2Very high97.2Very high102 Ų10247.6 Ų47.639%0.38523%0.229SC..Hα-helixtrans-59.5-44.1-179.8-81.2-177.3-69172.3-0111.7P88 E89 A94 L95 H96 G102P88-R92 WeakPolarHBondContact O-CB 3.48Å; P88-R92 VanDerWaalsContact O-CG 3.24Å; P88-R92 WeakPolarHBondContact O-CG 3.31Å; P88-R92 PolarHBondContact O-N 2.92Å; P88-R92 VanDerWaalsContact O-N 3.1Å; P88-R92 PolarHBondContact O-NE 3.03Å; P88-R92 VanDerWaalsContact O-NE 3.11Å; E89-R92 PolarHBondContact O-N 3.1Å; R92-A94 PolarHBondContact O-N 3.03Å; R92-L95 PolarHBondContact O-N 3.34Å; R92-H96 VanDerWaalsContact O-CG 3.26Å; R92-H96 PolarHBondContact O-N 2.95Å; R92-H96 PolarHBondContact O-ND1 3.23Å; R92-G102 WeakPolarHBondContact CD-O 3.45Å; R92-G102 WeakPolarHBondContact CG-O 3.42Å
93K98Very high97.2Very high136 Ų13646.9 Ų46.959%0.59123%0.226SC*.Hα-helixtrans-57-49.6175.5-176.8-175.8173.5-172.20111.5E89 I90 I91 L95 H96 E97E89-K93 WeakPolarHBondContact O-CB 3.39Å; E89-K93 PolarHBondContact O-N 3.22Å; I90-K93 PolarHBondContact O-N 3.18Å; I91-K93 VanDerWaalsContact C-N 3.32Å; I91-K93 PolarHBondContact O-N 2.9Å; K93-L95 VanDerWaalsContact C-N 3.32Å; K93-L95 PolarHBondContact O-N 2.73Å; K93-H96 PolarHBondContact O-N 3.35Å; K93-E97 WeakPolarHBondContact CE-OE1 3.43Å; K93-E97 WeakPolarHBondContact O-CG 3.44Å; K93-E97 PolarHBondContact O-N 3.06Å; K93-E97 VanDerWaalsContact O-N 3.07Å
94A98.3Very high97.2Very high1 Ų149.9 Ų49.91%0.00824%0.244CC..Hα-helixtrans-65.2-33.6179.700000113.3I90 I91 R92 A98 A259 A262 R263I90-A94 WeakPolarHBondContact O-CB 3.5Å; I90-A94 PolarHBondContact O-N 3.29Å; I91-A94 PolarHBondContact O-N 3.4Å; R92-A94 PolarHBondContact O-N 3.03Å; A94-A98 PolarHBondContact O-N 3.43Å; A94-A259 HydrophobicContact CB-CB 3.7Å; A94-A259 WeakPolarHBondContact CB-O 3.39Å; A94-A262 HydrophobicContact CB-CB 4.03Å; A94-R263 HydrophobicContact CB-CG 4.44Å
95L97.8Very high97.2Very high0 Ų050.4 Ų50.40%025%0.248CC..Hα-helixtrans-68.2-42.6174.2-70.7170000111.4I68 I91 R92 K93 E97 A98 N99 A100 A262 T266I68-L95 HydrophobicContact CB-CD1 3.88Å; I68-L95 HydrophobicContact CB-CD2 4.15Å; I68-L95 HydrophobicContact CG1-CD1 4.28Å; I68-L95 HydrophobicContact CG1-CD2 3.66Å; I68-L95 HydrophobicContact CG2-CD1 4.36Å; I91-L95 HydrophobicContact CG2-CD1 3.67Å; I91-L95 HydrophobicContact CG2-CG 4.26Å; I91-L95 VanDerWaalsContact O-CG 3.28Å; I91-L95 WeakPolarHBondContact O-CG 3.23Å; I91-L95 PolarHBondContact O-N 3.03Å; R92-L95 PolarHBondContact O-N 3.34Å; K93-L95 VanDerWaalsContact C-N 3.32Å; K93-L95 PolarHBondContact O-N 2.73Å; L95-E97 VanDerWaalsContact C-N 3.32Å; L95-E97 PolarHBondContact O-N 3.29Å; L95-A98 CarbonylContact O-C 3.37Å; L95-A98 WeakPolarHBondContact O-CA 3.31Å; L95-A98 PolarHBondContact O-N 2.84Å; L95-N99 PolarHBondContact O-N 2.87Å; L95-A100 CarbonylContact C-O 3.6Å; L95-A100 HydrophobicContact CB-CB 4.16Å; L95-A100 HydrophobicContact CD2-CB 4.03Å; L95-A100 WeakPolarHBondContact O-CA 3.4Å; L95-A100 PolarHBondContact O-N 3.02Å; L95-A100 VanDerWaalsContact O-O 3.1Å; L95-A262 HydrophobicContact CD2-CB 4.18Å; L95-A262 VanDerWaalsContact CD2-O 3.24Å; L95-A262 WeakPolarHBondContact CD2-O 3.12Å; L95-A262 HydrophobicContact CG-CB 4.09Å; L95-T266 HydrophobicContact CD2-CG2 3.49Å; L95-T266 VanDerWaalsContact CD2-CG2 3.49Å
96H97Very high97.2Very high82 Ų8247.1 Ų47.138%0.3824%0.238SC..Hα-helixtrans-59.7-43.1175.7-67.7161000111.7D56 R92 K93 A98 N99 A100D56-H96 IonicContact OD1-CD2 2.75Å; D56-H96 IonicContact OD1-CE1 3.15Å; D56-H96 IonicContact OD1-NE2 2.71Å; D56-H96 PolarHBondContact OD1-NE2 3.37Å; D56-H96 IonicContact OD2-CE1 3.26Å; D56-H96 IonicContact OD2-NE2 2.73Å; D56-H96 PolarHBondContact OD2-NE2 2.82Å; R92-H96 VanDerWaalsContact O-CG 3.26Å; R92-H96 PolarHBondContact O-N 2.95Å; R92-H96 PolarHBondContact O-ND1 3.23Å; K93-H96 PolarHBondContact O-N 3.35Å; H96-A98 PolarHBondContact O-N 3.39Å; H96-N99 PolarHBondContact O-N 2.88Å; H96-A100 PolarHBondContact CD2-O 3.19Å; H96-A100 PolarHBondContact N-O 2.89Å
97E96.2Very high97.3Very high111 Ų11145 Ų4552%0.51924%0.242SC..Hα-helixtrans-58.1-30.1173.2-69.2166.2-175.700112.6K93 L95 R263K93-E97 WeakPolarHBondContact CE-OE1 3.43Å; K93-E97 WeakPolarHBondContact O-CG 3.44Å; K93-E97 PolarHBondContact O-N 3.06Å; K93-E97 VanDerWaalsContact O-N 3.07Å; L95-E97 VanDerWaalsContact C-N 3.32Å; L95-E97 PolarHBondContact O-N 3.29Å; E97-R263 IonicContact OE2-NH1 2.89Å; E97-R263 PolarHBondContact OE2-NH1 3.26Å
98A93.9Very high97.3Very high36 Ų3645.1 Ų45.130%0.29824%0.244SC..THydrogen-bonded Turntrans-95.116176.400000114.2A94 L95 H96 A100 R263A94-A98 PolarHBondContact O-N 3.43Å; L95-A98 CarbonylContact O-C 3.37Å; L95-A98 WeakPolarHBondContact O-CA 3.31Å; L95-A98 PolarHBondContact O-N 2.84Å; H96-A98 PolarHBondContact O-N 3.39Å; A98-A100 VanDerWaalsContact C-N 3.25Å; A98-A100 PolarHBondContact O-N 3.17Å; A98-R263 HydrophobicContact CB-CG 4.13Å
99N93.5Very high97.3Very high96 Ų9647.1 Ų47.151%0.51326%0.256SS..THydrogen-bonded Turntrans56.434.6-176.4-63.6-69.7000114.2R65 L95 H96R65-N99 WeakPolarHBondContact CB-O 3.47Å; R65-N99 VanDerWaalsContact CD-O 3.25Å; R65-N99 WeakPolarHBondContact CD-O 3.28Å; R65-N99 VanDerWaalsContact CG-O 3.29Å; R65-N99 WeakPolarHBondContact CG-O 3.49Å; R65-N99 PolarHBondContact NH2-OD1 2.8Å; L95-N99 PolarHBondContact O-N 2.87Å; H96-N99 PolarHBondContact O-N 2.88Å
100A95.2Very high97.2Very high1 Ų142 Ų421%0.00824%0.235CC..  trans-120.6164.717500000111N66 L95 H96 A98 T266N66-A100 HydrophobicContact CB-CB 4.11Å; L95-A100 CarbonylContact C-O 3.6Å; L95-A100 HydrophobicContact CB-CB 4.16Å; L95-A100 HydrophobicContact CD2-CB 4.03Å; L95-A100 WeakPolarHBondContact O-CA 3.4Å; L95-A100 PolarHBondContact O-N 3.02Å; L95-A100 VanDerWaalsContact O-O 3.1Å; H96-A100 PolarHBondContact CD2-O 3.19Å; H96-A100 PolarHBondContact N-O 2.89Å; A98-A100 VanDerWaalsContact C-N 3.25Å; A98-A100 PolarHBondContact O-N 3.17Å; A100-T266 HydrophobicContact CB-CG2 3.59Å
101V96.7Very high96.9Very high1 Ų141.7 Ų41.71%0.00623%0.233CC..EExtended strand (participates in β ladder)trans-112144.8174.8-179.10000108.7D56 L60 N66 N67 I68 Q103D56-V101 HydrophobicContact CB-CG1 4.06Å; D56-V101 HydrophobicContact CB-CG2 4.3Å; L60-V101 HydrophobicContact CD1-CG1 4.15Å; L60-V101 HydrophobicContact CD2-CB 4.08Å; L60-V101 HydrophobicContact CD2-CG1 4.33Å; L60-V101 HydrophobicContact CD2-CG2 4.22Å; L60-V101 HydrophobicContact CG-CB 4.4Å; L60-V101 HydrophobicContact CG-CG1 4.31Å; L60-V101 HydrophobicContact CG-CG2 4.22Å; N66-V101 PolarHBondContact O-N 2.89Å; N67-V101 CarbonylContact C-O 3.6Å; N67-V101 WeakPolarHBondContact CA-O 3.22Å; N67-V101 PolarHBondContact OD1-O 3.22Å; I68-V101 PolarHBondContact N-O 3.31Å; V101-Q103 HydrophobicContact CG1-CG 4.38Å
102G97.2Very high96.7Very high3 Ų343 Ų433%0.03124%0.242CC..EExtended strand (participates in β ladder)trans-122.2135.7173.200000111.5I68 R92I68-G102 WeakPolarHBondContact O-CA 3.29Å; R92-G102 WeakPolarHBondContact CD-O 3.45Å; R92-G102 WeakPolarHBondContact CG-O 3.42Å
103Q97.6Very high96.3Very high33 Ų3338.6 Ų38.615%0.15423%0.226CC..EExtended strand (participates in β ladder)trans-133.7140.4174.4-59-178.2-98.700109.8G48 C52 N67 I68 A69 I70 V101 A105 F145G48-Q103 PolarHBondContact O-NE2 3.31Å; C52-Q103 PolarHBondContact SG-NE2 3.01Å; C52-Q103 VanDerWaalsContact SG-NE2 3.38Å; N67-Q103 PolarHBondContact ND2-OE1 3.25Å; N67-Q103 PolarHBondContact OD1-OE1 3.5Å; I68-Q103 PolarHBondContact O-N 2.84Å; A69-Q103 CarbonylContact C-O 3.54Å; I70-Q103 PolarHBondContact N-O 2.95Å; V101-Q103 HydrophobicContact CG1-CG 4.38Å; Q103-A105 PolarHBondContact O-N 2.8Å; Q103-A105 VanDerWaalsContact O-N 3.08Å; Q103-F145 HydrophobicContact CB-CE1 4.21Å
104V98.2Very high95.8Very high78 Ų7834.7 Ų34.747%0.47322%0.224SC..EExtended strand (participates in β ladder)trans-66.6110.7165.81790000107.5I70 T72 P88I70-V104 HydrophobicContact CB-CG2 4.31Å; I70-V104 WeakPolarHBondContact O-CA 3.49Å; T72-V104 HydrophobicContact CG2-CG1 4.13Å; P88-V104 HydrophobicContact CB-CG2 4.03Å; P88-V104 HydrophobicContact CG-CG2 4.15Å
105A97.9Very high95.5Very high11 Ų1138.7 Ų38.79%0.09125%0.248CC..EExtended strand (participates in β ladder)trans-84.5-28.2-177.300000111.4A69 I70 I71 Q103 G139 F145A69-A105 HydrophobicContact CB-CB 3.68Å; I70-A105 PolarHBondContact O-N 3.15Å; I71-A105 HydrophobicContact CD1-CB 3.77Å; Q103-A105 PolarHBondContact O-N 2.8Å; Q103-A105 VanDerWaalsContact O-N 3.08Å; A105-G139 VanDerWaalsContact O-CA 3.23Å; A105-G139 WeakPolarHBondContact O-CA 3.46Å; A105-F145 HydrophobicContact CB-CD2 4.29Å; A105-F145 HydrophobicContact CB-CE1 4.13Å; A105-F145 HydrophobicContact CB-CE2 3.44Å; A105-F145 VanDerWaalsContact CB-CE2 3.44Å; A105-F145 HydrophobicContact CB-CZ 3.35Å
106G97.6Very high95.3Very high17 Ų1739.7 Ų39.718%0.17525%0.254CS..EExtended strand (participates in β ladder)trans-175.9153.5177.300000112.3T72T72-G106 PolarHBondContact N-O 2.79Å
107G98.3Very high94.9Very high54 Ų5437.7 Ų37.756%0.55725%0.245SC*.EExtended strand (participates in β ladder)trans-94.2138.5163.700000109.8T72T72-G107 CarbonylContact O-C 3.51Å; T72-G107 VanDerWaalsContact O-CA 3.32Å; T72-G107 WeakPolarHBondContact O-CA 3.39Å
108V98.7Very high94.6Very high8 Ų832.5 Ų32.55%0.04822%0.221CC..  trans-107.6150.2168.5-600000109.6I71 T72 S73 A110 I132 A136 L161I71-V108 HydrophobicContact CG2-CG1 3.73Å; T72-V108 PolarHBondContact O-N 3.03Å; S73-V108 VanDerWaalsContact CB-CG2 3.47Å; V108-A110 PolarHBondContact O-N 3.34Å; V108-I132 HydrophobicContact CB-CG1 4.42Å; V108-I132 HydrophobicContact CB-CG2 4.09Å; V108-I132 HydrophobicContact CG1-CG2 4.33Å; V108-I132 HydrophobicContact CG2-CG2 4.09Å; V108-A136 HydrophobicContact CG1-CB 3.83Å; V108-L161 HydrophobicContact CG1-CD2 4.01Å; V108-L161 HydrophobicContact CG2-CD2 3.91Å
109P97.5Very high94.5Very high57 Ų5736.4 Ų36.437%0.3723%0.233SC..  trans-63.6139.5175.726.7-33.1000110.2V131 I132P109-V131 HydrophobicContact CG-CG1 3.87Å; P109-I132 HydrophobicContact CG-CG1 3.88Å; P109-I132 VanDerWaalsContact O-CD1 3.31Å; P109-I132 WeakPolarHBondContact O-CD1 3.23Å; P109-I132 VanDerWaalsContact O-CG1 3.3Å; P109-I132 WeakPolarHBondContact O-CG1 3.45Å
110A96.2Very high94.5Very high15 Ų1535.1 Ų35.112%0.12423%0.226CC..  trans-109.7114.5172.400000108.6S73 N75 L78 V108 I157S73-A110 VanDerWaalsContact O-CB 3.26Å; S73-A110 WeakPolarHBondContact O-CB 3.32Å; N75-A110 HydrophobicContact CB-CB 3.86Å; L78-A110 HydrophobicContact CD1-CB 3.76Å; L78-A110 WeakPolarHBondContact CD1-O 3.21Å; V108-A110 PolarHBondContact O-N 3.34Å; A110-I157 HydrophobicContact CB-CD1 3.77Å
111M93.5Very high94.6Very high34 Ų3435.5 Ų35.517%0.16723%0.231CC..  trans-105.4137.2172.6-172.9164.8-153.200109.3T116 G121 L124 S125M111-T116 HydrophobicContact CE-CG2 3.63Å; M111-G121 WeakPolarHBondContact CE-O 3.24Å; M111-L124 HydrophobicContact CE-CB 4.24Å; M111-S125 VanDerWaalsContact SD-CA 3.52Å
112C92.9Very high94.5Very high27 Ų2735.5 Ų35.518%0.18223%0.231CC..  trans-114.6117.6173.6-178.60000109.6L78 G114 V115 T116L78-C112 HydrophobicContact CD1-CB 3.85Å; L78-C112 HydrophobicContact CD2-CB 3.41Å; L78-C112 VanDerWaalsContact CD2-CB 3.41Å; L78-C112 HydrophobicContact CG-CB 4.16Å; C112-G114 PolarHBondContact O-N 2.84Å; C112-G114 PolarHBondContact SG-N 3.17Å; C112-G114 VanDerWaalsContact SG-N 3.43Å; C112-V115 HydrophobicContact CB-CB 4.44Å; C112-V115 HydrophobicContact CB-CG2 3.97Å; C112-V115 WeakPolarHBondContact O-CB 3.47Å; C112-V115 PolarHBondContact O-N 3.22Å; C112-T116 PolarHBondContact O-N 2.99Å
113D90Very high94.5Very high10 Ų1036.3 Ų36.35%0.05323%0.234CC..Hα-helixtrans-58.6-33.4176.1-66-29.1000111.3V115 T116 Q117 M122 S125 D155 K156D113-V115 PolarHBondContact O-N 3.49Å; D113-V115 VanDerWaalsContact O-N 3.14Å; D113-T116 PolarHBondContact O-N 2.98Å; D113-T116 VanDerWaalsContact O-N 3.08Å; D113-Q117 WeakPolarHBondContact O-CB 3.35Å; D113-Q117 WeakPolarHBondContact O-CG 3.02Å; D113-Q117 PolarHBondContact O-N 2.96Å; D113-M122 HydrophobicContact CB-CE 3.81Å; D113-M122 HydrophobicContact CB-SD 4.23Å; D113-M122 VanDerWaalsContact CG-CE 3.44Å; D113-M122 VanDerWaalsContact OD1-CE 3.23Å; D113-M122 WeakPolarHBondContact OD1-CE 3.44Å; D113-S125 VanDerWaalsContact OD1-CB 3.29Å; D113-S125 WeakPolarHBondContact OD1-CB 3.06Å; D113-S125 PolarHBondContact OD1-OG 2.98Å; D113-D155 WeakPolarHBondContact OD2-CB 3.42Å; D113-K156 IonicContact OD1-NZ 3.02Å; D113-K156 IonicContact OD2-NZ 3.09Å; D113-K156 PolarHBondContact OD2-NZ 2.77Å
114G88.6Confident94.5Very high53 Ų5335.6 Ų35.655%0.54623%0.231SC..Hα-helixtrans-60.1-23.3175.500000114.4C112C112-G114 PolarHBondContact O-N 2.84Å; C112-G114 PolarHBondContact SG-N 3.17Å; C112-G114 VanDerWaalsContact SG-N 3.43Å
115V91.7Very high94.4Very high85 Ų8531.9 Ų31.952%0.51521%0.208SC..Hα-helixtrans-86.8-32.6175.5177.90000111.4L78 C112 D113L78-V115 HydrophobicContact CD2-CG2 3.85Å; C112-V115 HydrophobicContact CB-CB 4.44Å; C112-V115 HydrophobicContact CB-CG2 3.97Å; C112-V115 WeakPolarHBondContact O-CB 3.47Å; C112-V115 PolarHBondContact O-N 3.22Å; D113-V115 PolarHBondContact O-N 3.49Å; D113-V115 VanDerWaalsContact O-N 3.14Å
116T93Very high94.4Very high21 Ų2131.3 Ų31.313%0.12920%0.204CC..Hα-helixtrans-103.1-7.5-172.357.30000114.9M111 C112 D113 G118 Q119 M122M111-T116 HydrophobicContact CE-CG2 3.63Å; C112-T116 PolarHBondContact O-N 2.99Å; D113-T116 PolarHBondContact O-N 2.98Å; D113-T116 VanDerWaalsContact O-N 3.08Å; T116-G118 PolarHBondContact O-N 3.2Å; T116-Q119 WeakPolarHBondContact O-CB 3.43Å; T116-Q119 PolarHBondContact O-N 2.84Å; T116-M122 PolarHBondContact OG1-SD 3.37Å; T116-M122 VanDerWaalsContact OG1-SD 3.37Å
117Q89.2Confident94.4Very high41 Ų4130.5 Ų30.519%0.19220%0.196CC..THydrogen-bonded Turntrans-53.5125-177.4-93.9170.917.500112.3D113 Q119 M122 H488D113-Q117 WeakPolarHBondContact O-CB 3.35Å; D113-Q117 WeakPolarHBondContact O-CG 3.02Å; D113-Q117 PolarHBondContact O-N 2.96Å; Q117-Q119 PolarHBondContact O-N 3.15Å; Q117-M122 HydrophobicContact CG-SD 4.29Å; Q117-H488 HydrophobicContact CB-CB 4.05Å; Q117-H488 HydrophobicContact CG-CB 3.91Å
118G88.7Confident94.4Very high1 Ų128.4 Ų28.41%0.0117%0.172CC..THydrogen-bonded Turntrans74.19.3-179.300000115.2T116 K489T116-G118 PolarHBondContact O-N 3.2Å; G118-K489 WeakPolarHBondContact O-CE 3.47Å; G118-K489 PolarHBondContact O-NZ 2.82Å
119Q93.3Very high94.4Very high118 Ų11828 Ų2855%0.55117%0.17SC*.SBendtrans-115161.1174.6-50.1-59.6-36.200110.6T116 Q117 G121 M122T116-Q119 WeakPolarHBondContact O-CB 3.43Å; T116-Q119 PolarHBondContact O-N 2.84Å; Q117-Q119 PolarHBondContact O-N 3.15Å; Q119-G121 PolarHBondContact O-N 2.73Å; Q119-G121 VanDerWaalsContact O-N 3.12Å; Q119-M122 VanDerWaalsContact O-CB 3.26Å; Q119-M122 WeakPolarHBondContact O-CB 3.28Å; Q119-M122 PolarHBondContact O-N 2.73Å
120D93.8Very high94.4Very high69 Ų6925.3 Ų25.337%0.36915%0.152SC..G310 helixtrans-53.4-34178.7-71.317.7000113.5M122 E123 R581D120-M122 PolarHBondContact O-N 3.03Å; D120-M122 VanDerWaalsContact O-N 3.09Å; D120-E123 WeakPolarHBondContact O-CB 3.42Å; D120-E123 PolarHBondContact O-N 2.95Å; D120-E123 VanDerWaalsContact O-N 3.09Å; D120-R581 IonicContact OD2-CZ 2.74Å; D120-R581 IonicContact OD2-NH1 3.29Å; D120-R581 PolarHBondContact OD2-NH1 2.88Å; D120-R581 IonicContact OD2-NH2 2.74Å; D120-R581 PolarHBondContact OD2-NH2 3.04Å
121G95.8Very high94.5Very high10 Ų1026.4 Ų26.410%0.10316%0.157CC..G310 helixtrans-57.6-24.6176.900000113.7M111 Q119 E123 L124M111-G121 WeakPolarHBondContact CE-O 3.24Å; Q119-G121 PolarHBondContact O-N 2.73Å; Q119-G121 VanDerWaalsContact O-N 3.12Å; G121-E123 PolarHBondContact O-N 2.94Å; G121-L124 PolarHBondContact O-N 2.81Å
122M96Very high94.8Very high1 Ų124.8 Ų24.81%0.00515%0.149CC..G310 helixtrans-62.2-25.4178.2-161.367.8-157.500112.8D113 T116 Q117 Q119 D120 L124 S125 P485 E486D113-M122 HydrophobicContact CB-CE 3.81Å; D113-M122 HydrophobicContact CB-SD 4.23Å; D113-M122 VanDerWaalsContact CG-CE 3.44Å; D113-M122 VanDerWaalsContact OD1-CE 3.23Å; D113-M122 WeakPolarHBondContact OD1-CE 3.44Å; T116-M122 PolarHBondContact OG1-SD 3.37Å; T116-M122 VanDerWaalsContact OG1-SD 3.37Å; Q117-M122 HydrophobicContact CG-SD 4.29Å; Q119-M122 VanDerWaalsContact O-CB 3.26Å; Q119-M122 WeakPolarHBondContact O-CB 3.28Å; Q119-M122 PolarHBondContact O-N 2.73Å; D120-M122 PolarHBondContact O-N 3.03Å; D120-M122 VanDerWaalsContact O-N 3.09Å; M122-L124 PolarHBondContact O-N 2.89Å; M122-S125 WeakPolarHBondContact O-CB 3.36Å; M122-S125 PolarHBondContact O-N 3.41Å; M122-P485 HydrophobicContact CB-CB 3.99Å; M122-P485 HydrophobicContact CG-CB 3.78Å; M122-E486 HydrophobicContact CE-CB 3.48Å; M122-E486 VanDerWaalsContact CE-CB 3.48Å; M122-E486 HydrophobicContact CE-CG 3.45Å; M122-E486 VanDerWaalsContact CE-CG 3.45Å
123E96.5Very high95.1Very high19 Ų1923.8 Ų23.89%0.08914%0.143CC..G310 helixtrans-65.9-14.7174.9-66.8-173.9169.300112.7D120 G121 N482 P485 S575 R581D120-E123 WeakPolarHBondContact O-CB 3.42Å; D120-E123 PolarHBondContact O-N 2.95Å; D120-E123 VanDerWaalsContact O-N 3.09Å; G121-E123 PolarHBondContact O-N 2.94Å; E123-N482 WeakPolarHBondContact CA-O 3.4Å; E123-N482 WeakPolarHBondContact CB-O 3.32Å; E123-N482 HydrophobicContact CG-CB 4.28Å; E123-N482 WeakPolarHBondContact CG-O 3.4Å; E123-P485 HydrophobicContact CG-CB 4.33Å; E123-P485 HydrophobicContact CG-CG 4.26Å; E123-S575 PolarHBondContact OE1-OG 2.85Å; E123-S575 WeakPolarHBondContact OE2-CB 3.49Å; E123-R581 IonicContact OE1-NH1 2.66Å; E123-R581 WeakPolarHBondContact OE2-CD 3.44Å; E123-R581 IonicContact OE2-CZ 2.71Å; E123-R581 IonicContact OE2-NE 3.59Å; E123-R581 IonicContact OE2-NH1 3.65Å; E123-R581 PolarHBondContact OE2-NH1 3.05Å
124L97.3Very high95.5Very high18 Ų1827 Ų279%0.09416%0.159CC..G310 helixtrans-97.1-7.4172.7-60-175.2000113.4M111 G121 M122 L127 S128 T579 R581 F584M111-L124 HydrophobicContact CE-CB 4.24Å; G121-L124 PolarHBondContact O-N 2.81Å; M122-L124 PolarHBondContact O-N 2.89Å; L124-L127 HydrophobicContact CD2-CD1 4.17Å; L124-L127 PolarHBondContact O-N 2.81Å; L124-S128 PolarHBondContact O-N 3.23Å; L124-T579 WeakPolarHBondContact CD1-O 3.38Å; L124-R581 HydrophobicContact CD2-CG 4.03Å; L124-R581 HydrophobicContact CG-CG 4.28Å; L124-F584 HydrophobicContact CD1-CD2 4.17Å; L124-F584 HydrophobicContact CD1-CE2 3.79Å; L124-F584 HydrophobicContact CD1-CZ 4.31Å; L124-F584 HydrophobicContact CD2-CB 4.1Å; L124-F584 HydrophobicContact CD2-CD1 4.18Å; L124-F584 HydrophobicContact CD2-CD2 3.48Å; L124-F584 VanDerWaalsContact CD2-CD2 3.48Å; L124-F584 HydrophobicContact CD2-CE1 4.46Å; L124-F584 HydrophobicContact CD2-CE2 3.87Å; L124-F584 HydrophobicContact CD2-CG 3.67Å; L124-F584 HydrophobicContact CD2-CZ 4.33Å; L124-F584 HydrophobicContact CG-CD2 4.45Å; L124-F584 HydrophobicContact CG-CE2 4.4Å
125S96.7Very high95.9Very high0 Ų026.3 Ų26.30%015%0.145CC..Hα-helixtrans-58-55.7-175169.40000112.3M111 D113 M122 L127 S128 K156 R511M111-S125 VanDerWaalsContact SD-CA 3.52Å; D113-S125 VanDerWaalsContact OD1-CB 3.29Å; D113-S125 WeakPolarHBondContact OD1-CB 3.06Å; D113-S125 PolarHBondContact OD1-OG 2.98Å; M122-S125 WeakPolarHBondContact O-CB 3.36Å; M122-S125 PolarHBondContact O-N 3.41Å; S125-L127 VanDerWaalsContact C-N 3.34Å; S125-L127 PolarHBondContact O-N 3.08Å; S125-S128 WeakPolarHBondContact O-CB 3.23Å; S125-S128 PolarHBondContact O-N 3.48Å; S125-S128 PolarHBondContact O-OG 3.27Å; S125-K156 VanDerWaalsContact O-CG 3.29Å; S125-K156 WeakPolarHBondContact O-CG 3.29Å; S125-K156 WeakPolarHBondContact OG-CE 3.2Å; S125-K156 PolarHBondContact OG-NZ 2.82Å; S125-R511 PolarHBondContact OG-NH2 2.67Å
126L97.1Very high96.3Very high0 Ų022.2 Ų22.20%012%0.121CC..Hα-helixtrans-64-42.7-179.9-175.459.3000111.9S128 R129 G483 M484 A598L126-S128 PolarHBondContact O-N 3.24Å; L126-R129 WeakPolarHBondContact O-CB 3.41Å; L126-R129 PolarHBondContact O-N 2.92Å; L126-G483 WeakPolarHBondContact CB-O 3.24Å; L126-M484 HydrophobicContact CD2-CB 3.91Å; L126-M484 HydrophobicContact CD2-CE 3.72Å; L126-M484 HydrophobicContact CD2-SD 4.27Å; L126-A598 HydrophobicContact CD2-CB 3.69Å
127L97.9Very high96.5Very high0 Ų022.6 Ų22.60%013%0.126CC..Hα-helixtrans-59.4-30.5177.8-76.7159.3000112.6L124 S125 R129 E130 V131 F584 L587 R588 L591L124-L127 HydrophobicContact CD2-CD1 4.17Å; L124-L127 PolarHBondContact O-N 2.81Å; S125-L127 VanDerWaalsContact C-N 3.34Å; S125-L127 PolarHBondContact O-N 3.08Å; L127-R129 PolarHBondContact O-N 3.14Å; L127-E130 WeakPolarHBondContact O-CB 3.29Å; L127-E130 PolarHBondContact O-N 3.35Å; L127-V131 PolarHBondContact O-N 3.39Å; L127-F584 HydrophobicContact CB-CD1 3.81Å; L127-F584 HydrophobicContact CB-CE1 4.18Å; L127-F584 HydrophobicContact CD1-CB 3.93Å; L127-F584 HydrophobicContact CD1-CD1 4.18Å; L127-F584 HydrophobicContact CD1-CG 4.34Å; L127-F584 HydrophobicContact CD2-CD1 4.43Å; L127-F584 HydrophobicContact CG-CD1 4.37Å; L127-L587 HydrophobicContact CD2-CB 3.71Å; L127-R588 HydrophobicContact CD1-CB 4.37Å; L127-L591 HydrophobicContact CD2-CD1 3.87Å; L127-L591 HydrophobicContact CD2-CD2 4.33Å; L127-L591 HydrophobicContact CD2-CG 4.28Å; L127-L591 HydrophobicContact CG-CD1 4.23Å
128S97.9Very high97Very high10 Ų1025.2 Ų25.27%0.0714%0.144CC..Hα-helixtrans-59.9-30.1175.978.30000112.4L124 S125 L126 E130 V131 I132 K156L124-S128 PolarHBondContact O-N 3.23Å; S125-S128 WeakPolarHBondContact O-CB 3.23Å; S125-S128 PolarHBondContact O-N 3.48Å; S125-S128 PolarHBondContact O-OG 3.27Å; L126-S128 PolarHBondContact O-N 3.24Å; S128-E130 VanDerWaalsContact C-N 3.29Å; S128-E130 PolarHBondContact O-N 3.13Å; S128-V131 PolarHBondContact O-N 2.85Å; S128-I132 WeakPolarHBondContact O-CB 3.3Å; S128-I132 WeakPolarHBondContact O-CD1 3.49Å; S128-I132 WeakPolarHBondContact O-CG1 3.35Å; S128-I132 PolarHBondContact O-N 3.46Å; S128-K156 WeakPolarHBondContact OG-CB 3.17Å
129R98.4Very high97.4Very high0 Ų025.3 Ų25.30%015%0.146CC..Hα-helixtrans-56.5-45.5173.2-173.3-168.767.9-162.9-2111.2L126 L127 I132 A133 K156 P159 G160 M163 G597 A598 T599L126-R129 WeakPolarHBondContact O-CB 3.41Å; L126-R129 PolarHBondContact O-N 2.92Å; L127-R129 PolarHBondContact O-N 3.14Å; R129-I132 PolarHBondContact O-N 2.79Å; R129-A133 PolarHBondContact O-N 3.4Å; R129-K156 HydrophobicContact CB-CB 4.27Å; R129-P159 HydrophobicContact CG-CB 4.02Å; R129-G160 WeakPolarHBondContact O-CA 3.37Å; R129-M163 HydrophobicContact CG-SD 4.04Å; R129-G597 PolarHBondContact NH1-O 3.39Å; R129-G597 PolarHBondContact NH2-O 3.49Å; R129-G597 VanDerWaalsContact NH2-O 3.15Å; R129-A598 PolarHBondContact NH2-O 3.24Å; R129-T599 VanDerWaalsContact NH2-CA 3.32Å; R129-T599 VanDerWaalsContact NH2-CB 3.27Å
130E98.3Very high97.6Very high0 Ų019.9 Ų19.90%012%0.12CC..Hα-helixtrans-67.1-43.6-179.6-48.9-61.297.400110.4L127 S128 I132 A133 M134 L591 T599 C600 I601L127-E130 WeakPolarHBondContact O-CB 3.29Å; L127-E130 PolarHBondContact O-N 3.35Å; S128-E130 VanDerWaalsContact C-N 3.29Å; S128-E130 PolarHBondContact O-N 3.13Å; E130-I132 VanDerWaalsContact C-N 3.32Å; E130-I132 PolarHBondContact O-N 2.66Å; E130-A133 PolarHBondContact O-N 3.21Å; E130-M134 VanDerWaalsContact O-CG 3.28Å; E130-M134 WeakPolarHBondContact O-CG 3.44Å; E130-M134 PolarHBondContact O-N 2.77Å; E130-L591 HydrophobicContact CG-CD2 4.46Å; E130-T599 WeakPolarHBondContact OE2-CA 3.28Å; E130-T599 PolarHBondContact OE2-OG1 2.92Å; E130-C600 PolarHBondContact OE2-N 2.58Å; E130-C600 PolarHBondContact OE2-SG 2.99Å; E130-I601 HydrophobicContact CB-CD1 4.41Å; E130-I601 PolarHBondContact OE2-N 2.64Å
131V98.5Very high97.7Very high37 Ų3720 Ų2022%0.22413%0.127CC..Hα-helixtrans-63.3-39176.5177.90000111.4P109 L127 S128 M134 S135 F584 L587P109-V131 HydrophobicContact CG-CG1 3.87Å; L127-V131 PolarHBondContact O-N 3.39Å; S128-V131 PolarHBondContact O-N 2.85Å; V131-M134 PolarHBondContact O-N 2.58Å; V131-S135 VanDerWaalsContact O-CB 3.27Å; V131-S135 WeakPolarHBondContact O-CB 3.46Å; V131-S135 PolarHBondContact O-N 3.45Å; V131-S135 PolarHBondContact O-OG 2.99Å; V131-F584 HydrophobicContact CG2-CD1 4.38Å; V131-F584 HydrophobicContact CG2-CE1 3.55Å; V131-F584 HydrophobicContact CG2-CZ 4.3Å; V131-L587 HydrophobicContact CG2-CD1 4.25Å
132I98.8Very high97.7Very high0 Ų024.7 Ų24.70%015%0.146CC..Hα-helixtrans-62.9-45.1176.3-70.8164.6000110.5V108 P109 S128 R129 E130 M134 S135 A136 I157 L161V108-I132 HydrophobicContact CB-CG1 4.42Å; V108-I132 HydrophobicContact CB-CG2 4.09Å; V108-I132 HydrophobicContact CG1-CG2 4.33Å; V108-I132 HydrophobicContact CG2-CG2 4.09Å; P109-I132 HydrophobicContact CG-CG1 3.88Å; P109-I132 VanDerWaalsContact O-CD1 3.31Å; P109-I132 WeakPolarHBondContact O-CD1 3.23Å; P109-I132 VanDerWaalsContact O-CG1 3.3Å; P109-I132 WeakPolarHBondContact O-CG1 3.45Å; S128-I132 WeakPolarHBondContact O-CB 3.3Å; S128-I132 WeakPolarHBondContact O-CD1 3.49Å; S128-I132 WeakPolarHBondContact O-CG1 3.35Å; S128-I132 PolarHBondContact O-N 3.46Å; R129-I132 PolarHBondContact O-N 2.79Å; E130-I132 VanDerWaalsContact C-N 3.32Å; E130-I132 PolarHBondContact O-N 2.66Å; I132-M134 VanDerWaalsContact C-N 3.35Å; I132-M134 PolarHBondContact O-N 3.35Å; I132-S135 PolarHBondContact O-N 2.93Å; I132-A136 WeakPolarHBondContact O-CB 3.07Å; I132-A136 PolarHBondContact O-N 3.47Å; I132-I157 HydrophobicContact CD1-CB 4.2Å; I132-I157 HydrophobicContact CD1-CG1 3.78Å; I132-L161 HydrophobicContact CG2-CD2 3.82Å; I132-L161 HydrophobicContact CG2-CG 3.99Å
133A98.8Very high97.5Very high7 Ų727.2 Ų27.26%0.05816%0.159CC..Hα-helixtrans-59.6-46.6176.100000111.4R129 E130 A137 G160 M163 I601R129-A133 PolarHBondContact O-N 3.4Å; E130-A133 PolarHBondContact O-N 3.21Å; A133-A137 WeakPolarHBondContact O-CB 3.38Å; A133-A137 PolarHBondContact O-N 3Å; A133-G160 WeakPolarHBondContact CA-O 3.19Å; A133-G160 WeakPolarHBondContact CB-O 3.41Å; A133-M163 HydrophobicContact CB-CB 4Å; A133-M163 HydrophobicContact CB-CE 4.42Å; A133-I601 HydrophobicContact CB-CD1 3.95Å
134M98.5Very high97.4Very high78 Ų7826.8 Ų26.838%0.38416%0.158SC..Hα-helixtrans-64.7-43.3177.9-67.3175.3-172.900112.3E130 V131 I132 A137 V138 L587 I601E130-M134 VanDerWaalsContact O-CG 3.28Å; E130-M134 WeakPolarHBondContact O-CG 3.44Å; E130-M134 PolarHBondContact O-N 2.77Å; V131-M134 PolarHBondContact O-N 2.58Å; I132-M134 VanDerWaalsContact C-N 3.35Å; I132-M134 PolarHBondContact O-N 3.35Å; M134-A137 WeakPolarHBondContact O-CB 3.45Å; M134-A137 PolarHBondContact O-N 3.16Å; M134-V138 WeakPolarHBondContact O-CG2 3.34Å; M134-V138 PolarHBondContact O-N 3.33Å; M134-L587 HydrophobicContact CE-CD2 3.89Å; M134-I601 HydrophobicContact CE-CD1 4.2Å; M134-I601 HydrophobicContact CE-CG1 3.89Å
135S98.6Very high97.4Very high37 Ų3726.4 Ų26.426%0.25916%0.155SC..Hα-helixtrans-65.4-43.6179.3-69.30000112.4V131 I132 A137 V138 G139V131-S135 VanDerWaalsContact O-CB 3.27Å; V131-S135 WeakPolarHBondContact O-CB 3.46Å; V131-S135 PolarHBondContact O-N 3.45Å; V131-S135 PolarHBondContact O-OG 2.99Å; I132-S135 PolarHBondContact O-N 2.93Å; S135-A137 VanDerWaalsContact C-N 3.29Å; S135-A137 PolarHBondContact O-N 3.4Å; S135-V138 PolarHBondContact O-N 3.01Å; S135-G139 PolarHBondContact O-N 3.01Å; S135-G139 VanDerWaalsContact O-N 3.16Å
136A98.7Very high97.3Very high0 Ų026.9 Ų26.90%016%0.158CC..Hα-helixtrans-63.1-38.8174.200000111.2I71 V108 I132 V138 G139 L140 L161 A164I71-A136 HydrophobicContact CG2-CB 3.96Å; V108-A136 HydrophobicContact CG1-CB 3.83Å; I132-A136 WeakPolarHBondContact O-CB 3.07Å; I132-A136 PolarHBondContact O-N 3.47Å; A136-V138 VanDerWaalsContact C-N 3.35Å; A136-V138 PolarHBondContact O-N 3.49Å; A136-G139 PolarHBondContact O-N 3.03Å; A136-L140 WeakPolarHBondContact O-CG 3.46Å; A136-L140 PolarHBondContact O-N 3.4Å; A136-L161 HydrophobicContact CB-CD2 4.17Å; A136-A164 HydrophobicContact CB-CB 3.42Å; A136-A164 VanDerWaalsContact CB-CB 3.42Å
137A98.5Very high97.3Very high28 Ų2826.9 Ų26.923%0.23116%0.158CC..Hα-helixtrans-62.5-39.9175.400000112.5A133 M134 S135 G139 L140 S141 F168A133-A137 WeakPolarHBondContact O-CB 3.38Å; A133-A137 PolarHBondContact O-N 3Å; M134-A137 WeakPolarHBondContact O-CB 3.45Å; M134-A137 PolarHBondContact O-N 3.16Å; S135-A137 VanDerWaalsContact C-N 3.29Å; S135-A137 PolarHBondContact O-N 3.4Å; A137-G139 PolarHBondContact O-N 2.81Å; A137-L140 PolarHBondContact O-N 3.31Å; A137-S141 VanDerWaalsContact O-CB 3.26Å; A137-S141 WeakPolarHBondContact O-CB 3.33Å; A137-S141 PolarHBondContact O-N 3.49Å; A137-F168 HydrophobicContact CB-CE2 3.81Å; A137-F168 HydrophobicContact CB-CZ 4.47Å; A137-F168 WeakPolarHBondContact O-CZ 3.13Å
138V98.6Very high97.3Very high96 Ų9627 Ų2758%0.58216%0.158SC*.Hα-helixtrans-58.4-48.6173.3171.90000110.6M134 S135 A136 L140 S141M134-V138 WeakPolarHBondContact O-CG2 3.34Å; M134-V138 PolarHBondContact O-N 3.33Å; S135-V138 PolarHBondContact O-N 3.01Å; A136-V138 VanDerWaalsContact C-N 3.35Å; A136-V138 PolarHBondContact O-N 3.49Å; V138-L140 PolarHBondContact O-N 3.22Å; V138-S141 PolarHBondContact O-N 2.99Å; V138-S141 PolarHBondContact O-OG 2.82Å
139G97.9Very high97.3Very high4 Ų426.5 Ų26.54%0.04116%0.155CC..Hα-helixtrans-62.4-40.5178.800000113.6A105 S135 A136 A137 H142A105-G139 VanDerWaalsContact O-CA 3.23Å; A105-G139 WeakPolarHBondContact O-CA 3.46Å; S135-G139 PolarHBondContact O-N 3.01Å; S135-G139 VanDerWaalsContact O-N 3.16Å; A136-G139 PolarHBondContact O-N 3.03Å; A137-G139 PolarHBondContact O-N 2.81Å; G139-H142 PolarHBondContact O-CD2 3.35Å
140L97.9Very high97.4Very high3 Ų326.6 Ų26.62%0.01616%0.155CC..Hα-helixtrans-75.7-24.1178.8-66.1172.7000113A69 I71 A136 A137 V138 H142 N143 F145 A148 F150 F168A69-L140 HydrophobicContact CB-CD2 3.59Å; I71-L140 HydrophobicContact CD1-CD2 4.2Å; I71-L140 HydrophobicContact CD1-CG 4.13Å; I71-L140 HydrophobicContact CG1-CD2 4.23Å; I71-L140 HydrophobicContact CG1-CG 4.33Å; A136-L140 WeakPolarHBondContact O-CG 3.46Å; A136-L140 PolarHBondContact O-N 3.4Å; A137-L140 PolarHBondContact O-N 3.31Å; V138-L140 PolarHBondContact O-N 3.22Å; L140-H142 PolarHBondContact O-N 3.24Å; L140-N143 PolarHBondContact O-N 3.26Å; L140-N143 VanDerWaalsContact O-N 3.09Å; L140-F145 HydrophobicContact CD2-CD2 4.36Å; L140-A148 HydrophobicContact CD2-CB 4.17Å; L140-F150 HydrophobicContact CD1-CE1 4.29Å; L140-F150 HydrophobicContact CD1-CZ 4Å; L140-F168 HydrophobicContact CB-CD1 3.8Å; L140-F168 HydrophobicContact CB-CD2 3.91Å; L140-F168 HydrophobicContact CB-CE1 3.65Å; L140-F168 HydrophobicContact CB-CE2 3.81Å; L140-F168 HydrophobicContact CB-CG 3.92Å; L140-F168 HydrophobicContact CB-CZ 3.66Å; L140-F168 HydrophobicContact CD1-CB 4.18Å; L140-F168 HydrophobicContact CD1-CD2 3.73Å; L140-F168 HydrophobicContact CD1-CE2 4.3Å; L140-F168 HydrophobicContact CD1-CG 3.9Å; L140-F168 HydrophobicContact CG-CD2 4.49Å
141S96.2Very high97.4Very high73 Ų7326.6 Ų26.651%0.5116%0.155SC..THydrogen-bonded Turntrans-64.7-11.8-179.175.50000114.6A137 V138 N143A137-S141 VanDerWaalsContact O-CB 3.26Å; A137-S141 WeakPolarHBondContact O-CB 3.33Å; A137-S141 PolarHBondContact O-N 3.49Å; V138-S141 PolarHBondContact O-N 2.99Å; V138-S141 PolarHBondContact O-OG 2.82Å; S141-N143 PolarHBondContact O-N 2.66Å; S141-N143 VanDerWaalsContact O-N 3.1Å
142H94.5Very high97.3Very high108 Ų10825 Ų2550%0.515%0.146SC..THydrogen-bonded Turntrans-59.2-17.4169.7-64.1-47.7000113G139 L140 M144 F145G139-H142 PolarHBondContact O-CD2 3.35Å; L140-H142 PolarHBondContact O-N 3.24Å; H142-M144 PolarHBondContact O-N 2.85Å; H142-F145 HydrophobicContact CB-CE2 4.26Å
143N92.6Very high97.1Very high54 Ų5425 Ų2529%0.28915%0.147SC..  trans54.636.7174.2-16633.7000113.1L140 S141L140-N143 PolarHBondContact O-N 3.26Å; L140-N143 VanDerWaalsContact O-N 3.09Å; S141-N143 PolarHBondContact O-N 2.66Å; S141-N143 VanDerWaalsContact O-N 3.1Å
144M94.5Very high96.8Very high10 Ų1025.3 Ų25.35%0.04915%0.148CC..  trans-102.6-7.5-178.6-81.4-16366.100114L40 G48 N67 H142L40-M144 HydrophobicContact CD1-CG 3.73Å; G48-M144 WeakPolarHBondContact CA-SD 3.38Å; N67-M144 WeakPolarHBondContact CB-O 3.41Å; N67-M144 PolarHBondContact ND2-O 3.15Å; N67-M144 VanDerWaalsContact ND2-O 3.1Å; H142-M144 PolarHBondContact O-N 2.85Å
145F95.7Very high96.4Very high10 Ų1021.9 Ų21.94%0.04413%0.131CC..  trans-114.3146-160-50.5-67.5000111.3H36 N67 A69 Q103 A105 L140 H142 L171H36-F145 PolarHBondContact CD2-O 2.98Å; N67-F145 CarbonylContact O-C 3.54Å; N67-F145 VanDerWaalsContact O-CA 3.26Å; N67-F145 WeakPolarHBondContact O-CA 3.4Å; A69-F145 HydrophobicContact CB-CB 3.98Å; A69-F145 HydrophobicContact CB-CD1 3.79Å; A69-F145 HydrophobicContact CB-CD2 3.78Å; A69-F145 HydrophobicContact CB-CE1 4.2Å; A69-F145 HydrophobicContact CB-CE2 4.18Å; A69-F145 HydrophobicContact CB-CG 3.57Å; A69-F145 HydrophobicContact CB-CZ 4.39Å; Q103-F145 HydrophobicContact CB-CE1 4.21Å; A105-F145 HydrophobicContact CB-CD2 4.29Å; A105-F145 HydrophobicContact CB-CE1 4.13Å; A105-F145 HydrophobicContact CB-CE2 3.44Å; A105-F145 VanDerWaalsContact CB-CE2 3.44Å; A105-F145 HydrophobicContact CB-CZ 3.35Å; L140-F145 HydrophobicContact CD2-CD2 4.36Å; H142-F145 HydrophobicContact CB-CE2 4.26Å; F145-L171 WeakPolarHBondContact O-CD2 3.44Å
146D95.4Very high96.3Very high10 Ų1020.1 Ų20.15%0.05312%0.119CC..SBendtrans-108.9-3.2-178.6-52.9-62.5000111.7V35 H36 R37 N66 N67 P172 T269V35-D146 WeakPolarHBondContact CA-OD1 3.41Å; V35-D146 VanDerWaalsContact CB-OD1 3.3Å; V35-D146 WeakPolarHBondContact CB-OD1 3.49Å; H36-D146 IonicContact CD2-OD1 3.24Å; H36-D146 PolarHBondContact N-OD1 3.34Å; R37-D146 IonicContact NH1-OD2 3.7Å; R37-D146 PolarHBondContact NH1-OD2 3.49Å; N66-D146 WeakPolarHBondContact CA-OD2 3.48Å; N66-D146 HydrophobicContact CB-CB 4.38Å; N67-D146 PolarHBondContact N-OD2 2.92Å; N67-D146 PolarHBondContact O-N 2.94Å; D146-P172 VanDerWaalsContact O-CD 3.26Å; D146-P172 WeakPolarHBondContact O-CD 3.37Å; D146-T269 HydrophobicContact CB-CG2 4.48Å; D146-T269 WeakPolarHBondContact O-CG2 3.49Å
147G96.6Very high96.2Very high0 Ų020.1 Ų20.10%012%0.119CC..EExtended strand (participates in β ladder)trans-176.2170.2175.600000110.4I68 A69 P172I68-G147 WeakPolarHBondContact CA-O 3.38Å; A69-G147 PolarHBondContact N-O 3.21Å; G147-P172 CarbonylContact C-O 3.31Å; G147-P172 VanDerWaalsContact CA-O 3.27Å; G147-P172 WeakPolarHBondContact CA-O 3.38Å
148A98.5Very high96.2Very high1 Ų119 Ų191%0.00811%0.109CC..EExtended strand (participates in β ladder)trans-141.6144-176.200000113.8A69 L140 F150 P172 A173 V174A69-A148 HydrophobicContact CB-CB 3.94Å; A69-A148 CarbonylContact O-C 3.56Å; A69-A148 WeakPolarHBondContact O-CA 3.41Å; L140-A148 HydrophobicContact CD2-CB 4.17Å; A148-F150 HydrophobicContact CB-CD2 4.32Å; A148-F150 HydrophobicContact CB-CE2 3.54Å; A148-F150 HydrophobicContact CB-CZ 3.86Å; A148-P172 PolarHBondContact N-O 3.01Å; A148-A173 VanDerWaalsContact O-CA 3.29Å; A148-A173 WeakPolarHBondContact O-CA 3.44Å; A148-V174 PolarHBondContact O-N 3.46Å
149L98.9Very high96.2Very high0 Ų014.4 Ų14.40%08%0.081CC..EExtended strand (participates in β ladder)trans-108.1130.4168.3-66.3164.1000109.1I68 A69 I71 I91 L151 V174 V176 A261 A262 V265I68-L149 HydrophobicContact CG2-CD1 4.06Å; I68-L149 HydrophobicContact CG2-CG 4.03Å; A69-L149 PolarHBondContact O-N 3.25Å; I71-L149 PolarHBondContact N-O 3.28Å; I91-L149 HydrophobicContact CB-CD1 4.43Å; I91-L149 HydrophobicContact CD1-CD1 4.08Å; I91-L149 HydrophobicContact CG1-CD1 4.18Å; I91-L149 HydrophobicContact CG2-CD1 3.4Å; L149-L151 HydrophobicContact CB-CD2 4.38Å; L149-V174 WeakPolarHBondContact CA-O 3.44Å; L149-V174 HydrophobicContact CD2-CB 3.94Å; L149-V174 HydrophobicContact CD2-CG1 4.47Å; L149-V176 HydrophobicContact CD2-CG2 3.9Å; L149-A261 HydrophobicContact CD2-CB 4.31Å; L149-A262 HydrophobicContact CD1-CB 3.98Å; L149-V265 HydrophobicContact CD1-CG1 4.49Å; L149-V265 HydrophobicContact CD2-CB 4.34Å; L149-V265 HydrophobicContact CD2-CG1 4.02Å; L149-V265 HydrophobicContact CG-CG1 4.11Å
150F98.9Very high96.2Very high2 Ų214.2 Ų14.21%0.0098%0.079CC..EExtended strand (participates in β ladder)trans-110.7108.9-178.8-67.9-85.7000109.4I71 L140 A148 L161 A165 A173 V174 F175 V176I71-F150 HydrophobicContact CB-CD1 4Å; I71-F150 HydrophobicContact CB-CE1 4.22Å; I71-F150 HydrophobicContact CG1-CD1 4.3Å; I71-F150 HydrophobicContact CG1-CE1 4.02Å; I71-F150 HydrophobicContact CG2-CD1 4.33Å; L140-F150 HydrophobicContact CD1-CE1 4.29Å; L140-F150 HydrophobicContact CD1-CZ 4Å; A148-F150 HydrophobicContact CB-CD2 4.32Å; A148-F150 HydrophobicContact CB-CE2 3.54Å; A148-F150 HydrophobicContact CB-CZ 3.86Å; F150-L161 HydrophobicContact CB-CB 4.48Å; F150-L161 HydrophobicContact CB-CD1 4.2Å; F150-L161 HydrophobicContact CD1-CB 3.98Å; F150-L161 HydrophobicContact CD1-CD2 4.04Å; F150-L161 HydrophobicContact CD1-CG 4.39Å; F150-A165 HydrophobicContact CD2-CB 4.23Å; F150-A165 HydrophobicContact CE1-CB 4.03Å; F150-A165 HydrophobicContact CE2-CB 3.54Å; F150-A165 HydrophobicContact CZ-CB 3.41Å; F150-A165 VanDerWaalsContact CZ-CB 3.41Å; F150-A173 HydrophobicContact CD2-CB 3.95Å; F150-A173 HydrophobicContact CE2-CB 3.53Å; F150-V174 PolarHBondContact N-O 3.33Å; F150-F175 HydrophobicContact CB-CD1 3.94Å; F150-F175 HydrophobicContact CB-CD2 4.16Å; F150-F175 HydrophobicContact CB-CE1 3.88Å; F150-F175 HydrophobicContact CB-CE2 4.06Å; F150-F175 HydrophobicContact CB-CG 4.08Å; F150-F175 HydrophobicContact CB-CZ 3.93Å; F150-F175 HydrophobicContact CD2-CD2 4.37Å; F150-F175 AromaticContact CD2-CE2 3.95Å; F150-F175 HydrophobicContact CD2-CE2 3.95Å; F150-F175 HydrophobicContact CD2-CZ 4.34Å; F150-F175 HydrophobicContact CG-CE1 4.47Å; F150-F175 HydrophobicContact CG-CE2 4.09Å; F150-F175 HydrophobicContact CG-CZ 4.04Å; F150-V176 PolarHBondContact O-N 3Å
151L98.7Very high96.3Very high0 Ų014.1 Ų14.10%08%0.079CC..EExtended strand (participates in β ladder)trans-99.998.5-178.3-41.1-173.9000108.4I70 I71 S73 Y84 I91 L149 V176I70-L151 HydrophobicContact CG2-CD1 3.62Å; I70-L151 HydrophobicContact CG2-CG 4.02Å; I71-L151 PolarHBondContact O-N 3.41Å; S73-L151 PolarHBondContact N-O 3.28Å; S73-L151 PolarHBondContact OG-O 3.08Å; Y84-L151 HydrophobicContact CD1-CB 3.71Å; Y84-L151 HydrophobicContact CD1-CD1 4.16Å; Y84-L151 HydrophobicContact CD1-CG 4.45Å; Y84-L151 HydrophobicContact CD2-CB 4.39Å; Y84-L151 HydrophobicContact CE1-CB 3.64Å; Y84-L151 HydrophobicContact CE2-CB 4.34Å; Y84-L151 HydrophobicContact CG-CB 4.09Å; I91-L151 HydrophobicContact CD1-CD1 4.06Å; I91-L151 HydrophobicContact CD1-CD2 3.88Å; L149-L151 HydrophobicContact CB-CD2 4.38Å; L151-V176 HydrophobicContact CD2-CB 3.58Å; L151-V176 HydrophobicContact CD2-CG1 4.22Å; L151-V176 HydrophobicContact CD2-CG2 3.81Å
152G97.5Very high96.4Very high3 Ų310.6 Ų10.63%0.0315%0.054CC..  trans-173.6148.1175.800000113S73 Y84 V158S73-G152 VanDerWaalsContact OG-CA 3.27Å; S73-G152 WeakPolarHBondContact OG-CA 3.42Å; Y84-G152 WeakPolarHBondContact OH-CA 3.39Å; Y84-G152 PolarHBondContact OH-N 3.19Å; G152-V158 WeakPolarHBondContact O-CG2 3.38Å
153V94.7Very high96.6Very high2 Ų25.5 Ų5.51%0.0123%0.031CC..  trans-137.9-20.3-175.9-72.30000115.4A80 H81 P177 T220 Q231A80-V153 HydrophobicContact CB-CG2 3.9Å; A80-V153 VanDerWaalsContact O-CG2 3.3Å; A80-V153 WeakPolarHBondContact O-CG2 3.35Å; H81-V153 PolarHBondContact NE2-N 3.31Å; H81-V153 VanDerWaalsContact NE2-N 3.17Å; V153-P177 HydrophobicContact CG1-CB 3.79Å; V153-T220 HydrophobicContact CB-CG2 3.78Å; V153-T220 HydrophobicContact CG2-CG2 3.49Å; V153-T220 VanDerWaalsContact CG2-CG2 3.49Å; V153-Q231 HydrophobicContact CG1-CG 4.32Å
154C91.7Very high96.9Very high13 Ų133 Ų39%0.0882%0.017CC..SBendtrans-70.2169.7-175-146.10000111.8H81 K156 I157 V158 N230H81-C154 PolarHBondContact CE1-N 3.27Å; H81-C154 VanDerWaalsContact CE1-N 3.32Å; C154-K156 PolarHBondContact O-N 2.84Å; C154-I157 HydrophobicContact CB-CB 4.48Å; C154-I157 HydrophobicContact CB-CD1 3.48Å; C154-I157 VanDerWaalsContact CB-CD1 3.48Å; C154-I157 HydrophobicContact CB-CG1 3.97Å; C154-I157 PolarHBondContact O-N 2.83Å; C154-V158 PolarHBondContact O-N 3.06Å; C154-N230 PolarHBondContact O-ND2 3.25Å
155D90.3Very high97.1Very high5 Ų52.6 Ų2.63%0.0272%0.016CC..THydrogen-bonded Turntrans-45.2-59.9-173.1-174-38.6000113.2D113 P159 T226 N230 N302 H306D113-D155 WeakPolarHBondContact OD2-CB 3.42Å; D155-P159 WeakPolarHBondContact O-CD 3.4Å; D155-P159 WeakPolarHBondContact O-CG 3.12Å; D155-T226 HydrophobicContact CB-CG2 4.08Å; D155-T226 WeakPolarHBondContact OD1-CG2 3.4Å; D155-T226 WeakPolarHBondContact OD2-CB 3.39Å; D155-T226 VanDerWaalsContact OD2-CG2 3.22Å; D155-T226 WeakPolarHBondContact OD2-CG2 3.44Å; D155-T226 PolarHBondContact OD2-OG1 3.49Å; D155-N230 WeakPolarHBondContact CA-ND2 3.43Å; D155-N230 PolarHBondContact O-ND2 2.79Å; D155-N302 PolarHBondContact OD2-ND2 2.9Å; D155-H306 IonicContact OD1-CD2 3.84Å; D155-H306 IonicContact OD1-CE1 2.73Å; D155-H306 IonicContact OD1-NE2 2.73Å; D155-H306 PolarHBondContact OD1-NE2 3.09Å
156K95.8Very high97.2Very high1 Ų12.2 Ų2.20%0.0041%0.014CC..THydrogen-bonded Turntrans-87.1-18.1-172.4-47.8-60.8-176.2-65.60112.9D113 S125 S128 R129 C154 G160 E486 R511D113-K156 IonicContact OD1-NZ 3.02Å; D113-K156 IonicContact OD2-NZ 3.09Å; D113-K156 PolarHBondContact OD2-NZ 2.77Å; S125-K156 VanDerWaalsContact O-CG 3.29Å; S125-K156 WeakPolarHBondContact O-CG 3.29Å; S125-K156 WeakPolarHBondContact OG-CE 3.2Å; S125-K156 PolarHBondContact OG-NZ 2.82Å; S128-K156 WeakPolarHBondContact OG-CB 3.17Å; R129-K156 HydrophobicContact CB-CB 4.27Å; C154-K156 PolarHBondContact O-N 2.84Å; K156-G160 PolarHBondContact O-N 3.02Å; K156-E486 IonicContact NZ-OE1 3.21Å; K156-R511 VanDerWaalsContact CE-CZ 3.43Å
157I97.6Very high97.3Very high0 Ų04.8 Ų4.80%03%0.033CC..Hα-helixtrans-72.4-52.6-173.2-57.4174.4000110.3S73 H81 A110 I132 C154 G160 L161S73-I157 WeakPolarHBondContact OG-CG2 3.17Å; H81-I157 VanDerWaalsContact CE1-CD1 3.4Å; H81-I157 WeakPolarHBondContact CE1-CD1 3.19Å; H81-I157 VanDerWaalsContact NE2-CD1 3.26Å; H81-I157 WeakPolarHBondContact NE2-CD1 3.48Å; A110-I157 HydrophobicContact CB-CD1 3.77Å; I132-I157 HydrophobicContact CD1-CB 4.2Å; I132-I157 HydrophobicContact CD1-CG1 3.78Å; C154-I157 HydrophobicContact CB-CB 4.48Å; C154-I157 HydrophobicContact CB-CD1 3.48Å; C154-I157 VanDerWaalsContact CB-CD1 3.48Å; C154-I157 HydrophobicContact CB-CG1 3.97Å; C154-I157 PolarHBondContact O-N 2.83Å; I157-G160 PolarHBondContact O-N 3.11Å; I157-L161 HydrophobicContact CG2-CD1 3.78Å; I157-L161 HydrophobicContact CG2-CG 4.12Å; I157-L161 WeakPolarHBondContact O-CB 3.4Å; I157-L161 VanDerWaalsContact O-CG 3.31Å; I157-L161 WeakPolarHBondContact O-CG 3.21Å; I157-L161 PolarHBondContact O-N 2.81Å
158V97.8Very high97.4Very high4 Ų46.6 Ų6.62%0.0244%0.041CC..Hα-helixtrans-58.1-50.2-178.8168.60000111.8G152 C154 G160 L161 T162 F175 N230 V234G152-V158 WeakPolarHBondContact O-CG2 3.38Å; C154-V158 PolarHBondContact O-N 3.06Å; V158-G160 VanDerWaalsContact C-N 3.35Å; V158-G160 PolarHBondContact O-N 3.09Å; V158-L161 PolarHBondContact O-N 2.99Å; V158-T162 WeakPolarHBondContact O-CB 3.46Å; V158-T162 PolarHBondContact O-N 2.86Å; V158-T162 PolarHBondContact O-OG1 3.3Å; V158-F175 HydrophobicContact CG1-CE1 4.44Å; V158-N230 HydrophobicContact CB-CB 3.96Å; V158-N230 HydrophobicContact CG1-CB 4.01Å; V158-N230 HydrophobicContact CG2-CB 4.08Å; V158-V234 HydrophobicContact CG1-CG2 3.44Å; V158-V234 VanDerWaalsContact CG1-CG2 3.44Å
159P98.2Very high97.4Very high0 Ų06.5 Ų6.50%04%0.04CC..Hα-helixtrans-60.9-40.5177.5-24.535000113.6R129 D155 T162 M163 H306 M310R129-P159 HydrophobicContact CG-CB 4.02Å; D155-P159 WeakPolarHBondContact O-CD 3.4Å; D155-P159 WeakPolarHBondContact O-CG 3.12Å; P159-T162 PolarHBondContact O-N 3.05Å; P159-M163 WeakPolarHBondContact O-CG 3.29Å; P159-M163 PolarHBondContact O-N 2.63Å; P159-H306 HydrophobicContact CB-CB 3.93Å; P159-H306 HydrophobicContact CG-CB 3.66Å; P159-M310 HydrophobicContact CB-CG 4.13Å; P159-M310 HydrophobicContact CB-SD 4.05Å; P159-M310 HydrophobicContact CG-SD 4.45Å
160G98.6Very high97.2Very high0 Ų07.5 Ų7.50%05%0.045CC..Hα-helixtrans-63.8-44.1176.900000112.3R129 A133 K156 I157 V158 M163 A164R129-G160 WeakPolarHBondContact O-CA 3.37Å; A133-G160 WeakPolarHBondContact CA-O 3.19Å; A133-G160 WeakPolarHBondContact CB-O 3.41Å; K156-G160 PolarHBondContact O-N 3.02Å; I157-G160 PolarHBondContact O-N 3.11Å; V158-G160 VanDerWaalsContact C-N 3.35Å; V158-G160 PolarHBondContact O-N 3.09Å; G160-M163 PolarHBondContact O-N 3.25Å; G160-A164 PolarHBondContact O-N 3.22Å
161L98.8Very high97.1Very high0 Ų07.9 Ų7.90%05%0.047CC..Hα-helixtrans-63.9-40175-68.2-178000111.5I71 V108 I132 A136 F150 I157 V158 A164 A165 F175I71-L161 HydrophobicContact CG2-CD2 3.7Å; V108-L161 HydrophobicContact CG1-CD2 4.01Å; V108-L161 HydrophobicContact CG2-CD2 3.91Å; I132-L161 HydrophobicContact CG2-CD2 3.82Å; I132-L161 HydrophobicContact CG2-CG 3.99Å; A136-L161 HydrophobicContact CB-CD2 4.17Å; F150-L161 HydrophobicContact CB-CB 4.48Å; F150-L161 HydrophobicContact CB-CD1 4.2Å; F150-L161 HydrophobicContact CD1-CB 3.98Å; F150-L161 HydrophobicContact CD1-CD2 4.04Å; F150-L161 HydrophobicContact CD1-CG 4.39Å; I157-L161 HydrophobicContact CG2-CD1 3.78Å; I157-L161 HydrophobicContact CG2-CG 4.12Å; I157-L161 WeakPolarHBondContact O-CB 3.4Å; I157-L161 VanDerWaalsContact O-CG 3.31Å; I157-L161 WeakPolarHBondContact O-CG 3.21Å; I157-L161 PolarHBondContact O-N 2.81Å; V158-L161 PolarHBondContact O-N 2.99Å; L161-A164 PolarHBondContact O-N 3.43Å; L161-A165 WeakPolarHBondContact O-CB 3.25Å; L161-A165 PolarHBondContact O-N 2.87Å; L161-F175 HydrophobicContact CB-CE1 3.79Å; L161-F175 HydrophobicContact CB-CZ 4.05Å
162T98.8Very high97.1Very high0 Ų07.9 Ų7.90%05%0.047CC..Hα-helixtrans-63.5-44.2175.9-61.10000111.6V158 P159 A164 A165 L166 F175 M239 M310V158-T162 WeakPolarHBondContact O-CB 3.46Å; V158-T162 PolarHBondContact O-N 2.86Å; V158-T162 PolarHBondContact O-OG1 3.3Å; P159-T162 PolarHBondContact O-N 3.05Å; T162-A164 VanDerWaalsContact C-N 3.31Å; T162-A164 PolarHBondContact O-N 3.28Å; T162-A165 PolarHBondContact O-N 2.98Å; T162-L166 HydrophobicContact CG2-CD1 3.77Å; T162-L166 HydrophobicContact CG2-CG 4.36Å; T162-L166 WeakPolarHBondContact O-CB 3.18Å; T162-L166 VanDerWaalsContact O-CG 3.29Å; T162-L166 WeakPolarHBondContact O-CG 3.31Å; T162-L166 PolarHBondContact O-N 2.99Å; T162-F175 WeakPolarHBondContact OG1-CZ 3.26Å; T162-M239 HydrophobicContact CG2-CE 3.92Å; T162-M310 VanDerWaalsContact CB-SD 3.59Å; T162-M310 HydrophobicContact CG2-CB 3.97Å; T162-M310 HydrophobicContact CG2-CG 3.73Å; T162-M310 HydrophobicContact CG2-SD 3.63Å
163M98.8Very high97.1Very high1 Ų17.9 Ų7.91%0.0055%0.046CC..Hα-helixtrans-59.8-41.4175.7-70.616166.300111.8R129 A133 P159 G160 S167 A309 M310 A313 I601 F603R129-M163 HydrophobicContact CG-SD 4.04Å; A133-M163 HydrophobicContact CB-CB 4Å; A133-M163 HydrophobicContact CB-CE 4.42Å; P159-M163 WeakPolarHBondContact O-CG 3.29Å; P159-M163 PolarHBondContact O-N 2.63Å; G160-M163 PolarHBondContact O-N 3.25Å; M163-S167 PolarHBondContact O-N 2.54Å; M163-S167 VanDerWaalsContact O-N 3.07Å; M163-S167 PolarHBondContact O-OG 2.69Å; M163-A309 HydrophobicContact CE-CB 4.49Å; M163-A309 HydrophobicContact SD-CB 4.04Å; M163-M310 HydrophobicContact CG-CG 4.46Å; M163-A313 HydrophobicContact CB-CB 4.35Å; M163-A313 HydrophobicContact CG-CB 4.29Å; M163-I601 HydrophobicContact CE-CD1 3.74Å; M163-F603 HydrophobicContact CB-CZ 4.17Å; M163-F603 HydrophobicContact CE-CE2 4.05Å; M163-F603 HydrophobicContact CE-CZ 3.66Å; M163-F603 HydrophobicContact CG-CZ 4.23Å
164A98.6Very high97.3Very high1 Ų17.8 Ų7.81%0.0085%0.046CC..Hα-helixtrans-66.7-47.4174.300000112.4A136 G160 L161 T162 L166 S167 F168A136-A164 HydrophobicContact CB-CB 3.42Å; A136-A164 VanDerWaalsContact CB-CB 3.42Å; G160-A164 PolarHBondContact O-N 3.22Å; L161-A164 PolarHBondContact O-N 3.43Å; T162-A164 VanDerWaalsContact C-N 3.31Å; T162-A164 PolarHBondContact O-N 3.28Å; A164-L166 VanDerWaalsContact C-N 3.26Å; A164-L166 PolarHBondContact O-N 3.4Å; A164-S167 WeakPolarHBondContact O-CB 3.17Å; A164-S167 PolarHBondContact O-N 3.24Å; A164-F168 WeakPolarHBondContact O-CD2 3.26Å; A164-F168 PolarHBondContact O-N 2.74Å; A164-F168 VanDerWaalsContact O-N 3.1Å
165A98.7Very high97.6Very high2 Ų27.4 Ų7.42%0.0174%0.043CC..Hα-helixtrans-57.1-41.6178.900000111.5F150 L161 T162 F168 G169 A173 F175 I278F150-A165 HydrophobicContact CD2-CB 4.23Å; F150-A165 HydrophobicContact CE1-CB 4.03Å; F150-A165 HydrophobicContact CE2-CB 3.54Å; F150-A165 HydrophobicContact CZ-CB 3.41Å; F150-A165 VanDerWaalsContact CZ-CB 3.41Å; L161-A165 WeakPolarHBondContact O-CB 3.25Å; L161-A165 PolarHBondContact O-N 2.87Å; T162-A165 PolarHBondContact O-N 2.98Å; A165-F168 CarbonylContact O-C 3.32Å; A165-F168 PolarHBondContact O-N 3.14Å; A165-G169 WeakPolarHBondContact O-CA 3.16Å; A165-G169 PolarHBondContact O-N 2.98Å; A165-G169 VanDerWaalsContact O-N 3.17Å; A165-A173 HydrophobicContact CB-CB 4.38Å; A165-F175 HydrophobicContact CB-CE2 4.41Å; A165-I278 HydrophobicContact CB-CD1 3.91Å; A165-I278 HydrophobicContact CB-CG2 4.48Å; A165-I278 WeakPolarHBondContact O-CG2 3.45Å
166L98.7Very high98Very high1 Ų17.3 Ų7.31%0.0054%0.042CC..Hα-helixtrans-70.9-30.6176.7-69.8168.9000113Y23 T162 A164 F168 G169 I278 I282 M310 A313 A314Y23-L166 VanDerWaalsContact CE2-O 3.28Å; Y23-L166 WeakPolarHBondContact CE2-O 3.35Å; Y23-L166 PolarHBondContact OH-O 2.87Å; T162-L166 HydrophobicContact CG2-CD1 3.77Å; T162-L166 HydrophobicContact CG2-CG 4.36Å; T162-L166 WeakPolarHBondContact O-CB 3.18Å; T162-L166 VanDerWaalsContact O-CG 3.29Å; T162-L166 WeakPolarHBondContact O-CG 3.31Å; T162-L166 PolarHBondContact O-N 2.99Å; A164-L166 VanDerWaalsContact C-N 3.26Å; A164-L166 PolarHBondContact O-N 3.4Å; L166-F168 PolarHBondContact O-N 2.95Å; L166-G169 WeakPolarHBondContact O-CA 3.47Å; L166-G169 PolarHBondContact O-N 3.46Å; L166-I278 HydrophobicContact CD2-CG1 4.26Å; L166-I282 HydrophobicContact CD2-CB 3.97Å; L166-I282 HydrophobicContact CD2-CG1 3.99Å; L166-I282 HydrophobicContact CD2-CG2 4.35Å; L166-M310 WeakPolarHBondContact CD1-O 3.25Å; L166-A313 HydrophobicContact CB-CB 3.92Å; L166-A313 HydrophobicContact CD1-CB 3.99Å; L166-A314 HydrophobicContact CD1-CB 4.01Å; L166-A314 HydrophobicContact CD2-CB 3.94Å; L166-A314 HydrophobicContact CG-CB 4.48Å
167S97.9Very high98.1Very high64 Ų647.4 Ų7.445%0.4484%0.043SC..Hα-helixtrans-65.3-30.9171.8-58.60000111.8M163 A164 G169M163-S167 PolarHBondContact O-N 2.54Å; M163-S167 VanDerWaalsContact O-N 3.07Å; M163-S167 PolarHBondContact O-OG 2.69Å; A164-S167 WeakPolarHBondContact O-CB 3.17Å; A164-S167 PolarHBondContact O-N 3.24Å; S167-G169 VanDerWaalsContact C-N 3.33Å
168F97.6Very high98.1Very high38 Ų387.4 Ų7.417%0.1674%0.043CC..THydrogen-bonded Turntrans-100.336.3169.5-67.4-98.9000111.3A137 L140 A164 A165 L166 H170 L171A137-F168 HydrophobicContact CB-CE2 3.81Å; A137-F168 HydrophobicContact CB-CZ 4.47Å; A137-F168 WeakPolarHBondContact O-CZ 3.13Å; L140-F168 HydrophobicContact CB-CD1 3.8Å; L140-F168 HydrophobicContact CB-CD2 3.91Å; L140-F168 HydrophobicContact CB-CE1 3.65Å; L140-F168 HydrophobicContact CB-CE2 3.81Å; L140-F168 HydrophobicContact CB-CG 3.92Å; L140-F168 HydrophobicContact CB-CZ 3.66Å; L140-F168 HydrophobicContact CD1-CB 4.18Å; L140-F168 HydrophobicContact CD1-CD2 3.73Å; L140-F168 HydrophobicContact CD1-CE2 4.3Å; L140-F168 HydrophobicContact CD1-CG 3.9Å; L140-F168 HydrophobicContact CG-CD2 4.49Å; A164-F168 WeakPolarHBondContact O-CD2 3.26Å; A164-F168 PolarHBondContact O-N 2.74Å; A164-F168 VanDerWaalsContact O-N 3.1Å; A165-F168 CarbonylContact O-C 3.32Å; A165-F168 PolarHBondContact O-N 3.14Å; L166-F168 PolarHBondContact O-N 2.95Å; F168-H170 PolarHBondContact O-N 3.2Å; F168-L171 HydrophobicContact CB-CD1 4.15Å; F168-L171 HydrophobicContact CB-CG 4.48Å; F168-L171 WeakPolarHBondContact O-CB 3.43Å; F168-L171 PolarHBondContact O-N 2.59Å
169G97.9Very high98Very high0 Ų07.2 Ų7.20%04%0.042CC..THydrogen-bonded Turntrans-63.1-1.6-167.300000116.8Y23 A165 L166 S167 P277 G279Y23-G169 WeakPolarHBondContact OH-CA 3.46Å; A165-G169 WeakPolarHBondContact O-CA 3.16Å; A165-G169 PolarHBondContact O-N 2.98Å; A165-G169 VanDerWaalsContact O-N 3.17Å; L166-G169 WeakPolarHBondContact O-CA 3.47Å; L166-G169 PolarHBondContact O-N 3.46Å; S167-G169 VanDerWaalsContact C-N 3.33Å; G169-P277 WeakPolarHBondContact O-CB 2.95Å; G169-G279 VanDerWaalsContact O-CA 3.29Å; G169-G279 WeakPolarHBondContact O-CA 3.24Å; G169-G279 PolarHBondContact O-N 3.16Å
170H96.3Very high97.9Very high21 Ų217.2 Ų7.210%0.0974%0.042CC..THydrogen-bonded Turntrans-84.1-14.6171.561-86.6000113I27 A30 H36 F168 W275 P277I27-H170 HydrophobicContact CG2-CB 4.04Å; A30-H170 HydrophobicContact CB-CB 3.85Å; A30-H170 WeakPolarHBondContact CB-ND1 3.36Å; H36-H170 AromaticContact CE1-CD2 3.25Å; H36-H170 PolarHBondContact CE1-CD2 3.43Å; H36-H170 AromaticContact CE1-NE2 3.55Å; H36-H170 AromaticContact NE2-CD2 3.55Å; F168-H170 PolarHBondContact O-N 3.2Å; H170-W275 PolarHBondContact O-NE1 3.32Å; H170-P277 VanDerWaalsContact O-CB 3.25Å; H170-P277 WeakPolarHBondContact O-CB 3.47Å
171L96.9Very high97.7Very high9 Ų97.3 Ų7.35%0.0474%0.042CC..SBendtrans-85.7139.9173-59.6-178.5000110.1F145 F168 I278F145-L171 WeakPolarHBondContact O-CD2 3.44Å; F168-L171 HydrophobicContact CB-CD1 4.15Å; F168-L171 HydrophobicContact CB-CG 4.48Å; F168-L171 WeakPolarHBondContact O-CB 3.43Å; F168-L171 PolarHBondContact O-N 2.59Å; L171-I278 WeakPolarHBondContact O-CG2 3.41Å; L171-I278 PolarHBondContact O-N 3.05Å
172P97.2Very high97.5Very high1 Ų19.7 Ų9.71%0.0066%0.062CC..  trans-60.1140.4159.5-18.832.1000110.2D146 G147 A148 V265 M268 T269D146-P172 VanDerWaalsContact O-CD 3.26Å; D146-P172 WeakPolarHBondContact O-CD 3.37Å; G147-P172 CarbonylContact C-O 3.31Å; G147-P172 VanDerWaalsContact CA-O 3.27Å; G147-P172 WeakPolarHBondContact CA-O 3.38Å; A148-P172 PolarHBondContact N-O 3.01Å; P172-V265 HydrophobicContact CB-CG2 4.08Å; P172-M268 HydrophobicContact CB-CB 3.71Å; P172-M268 HydrophobicContact CB-CE 4.31Å; P172-M268 HydrophobicContact CG-CB 4.11Å; P172-M268 WeakPolarHBondContact CG-O 3.45Å; P172-T269 HydrophobicContact CG-CG2 4.19Å
173A98.4Very high97.3Very high2 Ų212.7 Ų12.72%0.0178%0.083CC..EExtended strand (participates in β ladder)trans-138.7138.3179.300000111.1A148 F150 A165 I278A148-A173 VanDerWaalsContact O-CA 3.29Å; A148-A173 WeakPolarHBondContact O-CA 3.44Å; F150-A173 HydrophobicContact CD2-CB 3.95Å; F150-A173 HydrophobicContact CE2-CB 3.53Å; A165-A173 HydrophobicContact CB-CB 4.38Å; A173-I278 HydrophobicContact CB-CB 3.85Å; A173-I278 HydrophobicContact CB-CD1 3.69Å; A173-I278 HydrophobicContact CB-CG1 4.3Å; A173-I278 HydrophobicContact CB-CG2 4.02Å
174V98.7Very high96.9Very high0 Ų013.9 Ų13.90%010%0.095CC..EExtended strand (participates in β ladder)trans-129.9130.6173.7-178.80000109.1A148 L149 F150 A261 V265 M268 V373A148-V174 PolarHBondContact O-N 3.46Å; L149-V174 WeakPolarHBondContact CA-O 3.44Å; L149-V174 HydrophobicContact CD2-CB 3.94Å; L149-V174 HydrophobicContact CD2-CG1 4.47Å; F150-V174 PolarHBondContact N-O 3.33Å; V174-A261 HydrophobicContact CG1-CB 3.93Å; V174-V265 HydrophobicContact CB-CB 4.46Å; V174-V265 HydrophobicContact CG2-CB 3.81Å; V174-V265 HydrophobicContact CG2-CG2 4.26Å; V174-M268 HydrophobicContact CG2-SD 4.34Å; V174-V373 HydrophobicContact CB-CG1 4.48Å; V174-V373 HydrophobicContact CG2-CB 4.18Å; V174-V373 HydrophobicContact CG2-CG1 3.87Å
175F98.8Very high96.5Very high5 Ų516 Ų162%0.02211%0.106CC..EExtended strand (participates in β ladder)trans-86.8138.5174.5-80-112.2000110F150 V158 L161 T162 A165 V234 M239 Q240 I278F150-F175 HydrophobicContact CB-CD1 3.94Å; F150-F175 HydrophobicContact CB-CD2 4.16Å; F150-F175 HydrophobicContact CB-CE1 3.88Å; F150-F175 HydrophobicContact CB-CE2 4.06Å; F150-F175 HydrophobicContact CB-CG 4.08Å; F150-F175 HydrophobicContact CB-CZ 3.93Å; F150-F175 HydrophobicContact CD2-CD2 4.37Å; F150-F175 AromaticContact CD2-CE2 3.95Å; F150-F175 HydrophobicContact CD2-CE2 3.95Å; F150-F175 HydrophobicContact CD2-CZ 4.34Å; F150-F175 HydrophobicContact CG-CE1 4.47Å; F150-F175 HydrophobicContact CG-CE2 4.09Å; F150-F175 HydrophobicContact CG-CZ 4.04Å; V158-F175 HydrophobicContact CG1-CE1 4.44Å; L161-F175 HydrophobicContact CB-CE1 3.79Å; L161-F175 HydrophobicContact CB-CZ 4.05Å; T162-F175 WeakPolarHBondContact OG1-CZ 3.26Å; A165-F175 HydrophobicContact CB-CE2 4.41Å; F175-V234 HydrophobicContact CB-CG1 3.96Å; F175-V234 HydrophobicContact CD1-CG1 4.49Å; F175-V234 HydrophobicContact CG-CG1 4.17Å; F175-M239 HydrophobicContact CD2-CB 4.27Å; F175-M239 HydrophobicContact CD2-CE 3.5Å; F175-M239 VanDerWaalsContact CD2-CE 3.5Å; F175-M239 HydrophobicContact CE1-CE 4.38Å; F175-M239 HydrophobicContact CE2-CE 3.17Å; F175-M239 HydrophobicContact CG-CE 4.26Å; F175-M239 HydrophobicContact CZ-CE 3.67Å; F175-M239 PolarHBondContact N-O 2.96Å; F175-Q240 HydrophobicContact CB-CB 4.25Å; F175-Q240 VanDerWaalsContact O-CB 3.26Å; F175-Q240 WeakPolarHBondContact O-CB 3.16Å; F175-I278 HydrophobicContact CE2-CD1 4.32Å
176V98.7Very high96Very high3 Ų320.1 Ų20.12%0.01813%0.133CC..  trans-123.299.2-176.9-171.90000109.3Y84 Y87 L149 F150 L151 T258 A261Y84-V176 WeakPolarHBondContact CE1-O 3.48Å; Y84-V176 PolarHBondContact OH-O 2.96Å; Y87-V176 HydrophobicContact CD2-CG1 4.25Å; Y87-V176 HydrophobicContact CE2-CG1 4.21Å; L149-V176 HydrophobicContact CD2-CG2 3.9Å; F150-V176 PolarHBondContact O-N 3Å; L151-V176 HydrophobicContact CD2-CB 3.58Å; L151-V176 HydrophobicContact CD2-CG1 4.22Å; L151-V176 HydrophobicContact CD2-CG2 3.81Å; V176-T258 HydrophobicContact CG1-CG2 4.23Å; V176-A261 HydrophobicContact CG2-CB 3.84Å
177P97.8Very high95.3Very high3 Ų320.3 Ų20.32%0.01913%0.134CC..  trans-70.6152.2177.627.9-33.7000111.7V153 S244 R254V153-P177 HydrophobicContact CG1-CB 3.79Å; P177-S244 VanDerWaalsContact CG-O 3.27Å; P177-S244 WeakPolarHBondContact CG-O 3.49Å; P177-R254 PolarHBondContact O-NE 3.16Å; P177-R254 PolarHBondContact O-NH1 3.41Å
178S96.7Very high94.6Very high0 Ų025.8 Ų25.80%015%0.15CC..  trans-80.6-33.6167.866.30000112A80 Y84 P249 R254A80-S178 PolarHBondContact O-OG 2.93Å; Y84-S178 PolarHBondContact OH-N 3.35Å; S178-P249 WeakPolarHBondContact O-CG 3.47Å; S178-R254 PolarHBondContact O-NE 2.91Å; S178-R254 PolarHBondContact O-NH2 3.46Å
179G95.4Very high94.3Very high0 Ų027 Ų270%016%0.156CC..  trans91.1170.2-173.300000115G219 T220 S245 V247G179-G219 CarbonylContact O-C 3.5Å; G179-G219 VanDerWaalsContact O-CA 3.25Å; G179-G219 WeakPolarHBondContact O-CA 3.49Å; G179-T220 PolarHBondContact O-N 3Å; G179-S245 WeakPolarHBondContact CA-O 3.25Å; G179-V247 WeakPolarHBondContact CA-O 3.36Å
180P95.7Very high93.9Very high0 Ų027.1 Ų27.10%016%0.157CC..BIsolated β-bridgetrans-80.4155-178.633.9-36000112.4T220 F246 H248 P249 I344 N345P180-T220 VanDerWaalsContact CA-OG1 3.22Å; P180-T220 WeakPolarHBondContact CA-OG1 3.47Å; P180-F246 HydrophobicContact CG-CB 4.42Å; P180-F246 HydrophobicContact CG-CD1 4.33Å; P180-H248 PolarHBondContact O-ND1 3.46Å; P180-P249 WeakPolarHBondContact O-CD 3.41Å; P180-I344 HydrophobicContact CB-CG2 3.68Å; P180-I344 HydrophobicContact CG-CG2 3.96Å; P180-N345 WeakPolarHBondContact CG-OD1 3.03Å
181M95.2Very high93.5Very high2 Ų228.3 Ų28.31%0.0117%0.165CC..PPolyproline II helixtrans-67.4161.3163.967.6-171.164.800110.8A217 P218 G219 T220 T222 N345M181-A217 HydrophobicContact CB-CB 4.31Å; M181-A217 WeakPolarHBondContact CE-O 3.46Å; M181-P218 WeakPolarHBondContact CA-O 3.46Å; M181-P218 VanDerWaalsContact CB-O 3.31Å; M181-P218 WeakPolarHBondContact CB-O 3.25Å; M181-G219 VanDerWaalsContact CE-O 3.26Å; M181-G219 WeakPolarHBondContact CE-O 3.32Å; M181-T220 WeakPolarHBondContact CG-O 3.39Å; M181-T220 PolarHBondContact N-O 3.23Å; M181-T222 HydrophobicContact CG-CG2 3.63Å; M181-T222 WeakPolarHBondContact O-CG2 3.43Å; M181-N345 PolarHBondContact O-ND2 2.85Å
182A94.7Very high93.2Very high50 Ų5033.2 Ų33.241%0.41318%0.183SC..PPolyproline II helixtrans-61.5161.1171.800000111.9G184 H216 T222A182-G184 PolarHBondContact O-N 2.92Å; A182-H216 PolarHBondContact O-NE2 2.84Å; A182-T222 WeakPolarHBondContact O-CG2 3.27Å
183S93.9Very high93.1Very high63 Ų6334.2 Ų34.244%0.44119%0.188SC..PPolyproline II helixtrans-66.2119.3179-64.60000111.3D343 N345S183-D343 VanDerWaalsContact CB-OD2 3.23Å; S183-D343 WeakPolarHBondContact CB-OD2 3.29Å; S183-D343 VanDerWaalsContact OG-CG 3.3Å; S183-D343 PolarHBondContact OG-OD1 2.81Å; S183-D343 PolarHBondContact OG-OD2 3Å; S183-N345 PolarHBondContact N-ND2 3.41Å; S183-N345 VanDerWaalsContact N-ND2 3.12Å; S183-N345 WeakPolarHBondContact OG-CB 3.3Å; S183-N345 PolarHBondContact OG-ND2 3.26Å; S183-N345 VanDerWaalsContact OG-ND2 3.08Å
184G91.4Very high92.7Very high26 Ų2636 Ų3627%0.26819%0.194SC..  trans-100.2-140.4175.200000113A182 H216A182-G184 PolarHBondContact O-N 2.92Å; G184-H216 VanDerWaalsContact CA-CD2 3.48Å; G184-H216 WeakPolarHBondContact CA-CD2 3.42Å; G184-H216 VanDerWaalsContact CA-NE2 3.33Å; G184-H216 WeakPolarHBondContact CA-NE2 3.32Å; G184-H216 PolarHBondContact N-NE2 2.86Å
185L90.4Very high92.4Very high46 Ų4637.7 Ų37.724%0.24120%0.202CC..SBendtrans-54.8130.3175.6-171.975.2000111.2N187 E189 K190 S210 A213L185-N187 PolarHBondContact O-N 3.23Å; L185-E189 HydrophobicContact CD1-CB 4.43Å; L185-E189 HydrophobicContact CD1-CG 4.05Å; L185-E189 HydrophobicContact CD2-CG 4.38Å; L185-E189 HydrophobicContact CG-CB 4.36Å; L185-E189 HydrophobicContact CG-CG 4.37Å; L185-K190 HydrophobicContact CD2-CB 4.23Å; L185-S210 WeakPolarHBondContact CD2-O 3.32Å; L185-A213 HydrophobicContact CB-CB 4.11Å; L185-A213 PolarHBondContact N-O 3.39Å; L185-A213 VanDerWaalsContact N-O 3.12Å
186P87.7Confident92.2Very high88 Ų8839.1 Ų39.157%0.57121%0.21SC*.  trans-57134.3177.3-27.135.4000112.3K188 E189 K190P186-K188 PolarHBondContact O-N 3.07Å; P186-K188 VanDerWaalsContact O-N 3.12Å; P186-E189 WeakPolarHBondContact O-CB 3.5Å; P186-E189 PolarHBondContact O-N 2.92Å; P186-K190 PolarHBondContact O-N 2.89Å
187N83.9Confident91.9Very high6 Ų643.8 Ų43.83%0.03223%0.228CC..Hα-helixtrans-58.4-32.7-175.3-75.8-62000113.8L185 E189 K190 V191 Y337L185-N187 PolarHBondContact O-N 3.23Å; N187-E189 VanDerWaalsContact C-N 3.3Å; N187-E189 PolarHBondContact O-N 2.92Å; N187-K190 PolarHBondContact O-N 3.26Å; N187-K190 PolarHBondContact OD1-NZ 3.27Å; N187-V191 WeakPolarHBondContact O-CG2 3.28Å; N187-V191 PolarHBondContact O-N 3.38Å; N187-Y337 HydrophobicContact CB-CD1 3.31Å; N187-Y337 HydrophobicContact CB-CD2 3.64Å; N187-Y337 HydrophobicContact CB-CE1 3.52Å; N187-Y337 HydrophobicContact CB-CE2 3.81Å; N187-Y337 HydrophobicContact CB-CG 3.42Å; N187-Y337 VanDerWaalsContact CB-CG 3.42Å; N187-Y337 VanDerWaalsContact CG-CE1 3.45Å; N187-Y337 VanDerWaalsContact ND2-CD1 3.32Å; N187-Y337 WeakPolarHBondContact ND2-CD1 3.48Å; N187-Y337 WeakPolarHBondContact OD1-CE1 3.2Å
188K84.3Confident91.4Very high178 Ų17844.4 Ų44.477%0.77423%0.233SC*.Hα-helixtrans-61.6-39.4175.6-174.5176.6179.5-1800111.9P186 V191 R192P186-K188 PolarHBondContact O-N 3.07Å; P186-K188 VanDerWaalsContact O-N 3.12Å; K188-V191 PolarHBondContact O-N 3.23Å; K188-R192 WeakPolarHBondContact O-CB 3.4Å; K188-R192 PolarHBondContact O-N 3.38Å
189E90.8Very high91.2Very high63 Ų6347.6 Ų47.629%0.29425%0.248SC..Hα-helixtrans-71.2-41.7178.9-177.158.1-167.700111.1L185 P186 N187 V191 R192 I193L185-E189 HydrophobicContact CD1-CB 4.43Å; L185-E189 HydrophobicContact CD1-CG 4.05Å; L185-E189 HydrophobicContact CD2-CG 4.38Å; L185-E189 HydrophobicContact CG-CB 4.36Å; L185-E189 HydrophobicContact CG-CG 4.37Å; P186-E189 WeakPolarHBondContact O-CB 3.5Å; P186-E189 PolarHBondContact O-N 2.92Å; N187-E189 VanDerWaalsContact C-N 3.3Å; N187-E189 PolarHBondContact O-N 2.92Å; E189-V191 VanDerWaalsContact C-N 3.35Å; E189-V191 PolarHBondContact O-N 3.24Å; E189-R192 WeakPolarHBondContact O-CB 3.39Å; E189-R192 PolarHBondContact O-N 3.37Å; E189-R192 IonicContact OE1-CZ 3.59Å; E189-R192 IonicContact OE1-NE 2.9Å; E189-R192 PolarHBondContact OE1-NE 3.44Å; E189-R192 IonicContact OE1-NH2 2.77Å; E189-R192 PolarHBondContact OE1-NH2 3.12Å; E189-R192 IonicContact OE2-CZ 3.66Å; E189-R192 IonicContact OE2-NE 2.79Å; E189-R192 PolarHBondContact OE2-NE 2.94Å; E189-R192 IonicContact OE2-NH2 2.87Å; E189-I193 HydrophobicContact CG-CD1 4.18Å; E189-I193 WeakPolarHBondContact O-CG1 3.35Å; E189-I193 PolarHBondContact O-N 3.17Å
190K89.1Confident91Very high4 Ų450.6 Ų50.62%0.01728%0.279CS..Hα-helixtrans-55.2-47.9171.5-179.1176.864-169.20112.1L185 P186 N187 R192 I193 R194 S214 Y215L185-K190 HydrophobicContact CD2-CB 4.23Å; P186-K190 PolarHBondContact O-N 2.89Å; N187-K190 PolarHBondContact O-N 3.26Å; N187-K190 PolarHBondContact OD1-NZ 3.27Å; K190-R192 PolarHBondContact O-N 3.18Å; K190-I193 PolarHBondContact O-N 3.46Å; K190-R194 WeakPolarHBondContact O-CG 3.35Å; K190-R194 PolarHBondContact O-N 3.1Å; K190-S214 WeakPolarHBondContact CD-OG 3.44Å; K190-Y215 PolarHBondContact NZ-OH 3.32Å
191V87.7Confident91Very high45 Ų4556.8 Ų56.827%0.27331%0.306SS..Hα-helixtrans-62.6-43.1178.4171.90000111.4N187 K188 E189 I193 R194 Q195 Y337N187-V191 WeakPolarHBondContact O-CG2 3.28Å; N187-V191 PolarHBondContact O-N 3.38Å; K188-V191 PolarHBondContact O-N 3.23Å; E189-V191 VanDerWaalsContact C-N 3.35Å; E189-V191 PolarHBondContact O-N 3.24Å; V191-I193 VanDerWaalsContact C-N 3.31Å; V191-I193 PolarHBondContact O-N 3.12Å; V191-R194 WeakPolarHBondContact O-CB 3.48Å; V191-R194 PolarHBondContact O-N 3.43Å; V191-Q195 HydrophobicContact CG1-CG 4.4Å; V191-Q195 WeakPolarHBondContact O-CG 3.43Å; V191-Q195 PolarHBondContact O-N 3.21Å; V191-Y337 HydrophobicContact CG2-CE2 4.13Å; V191-Y337 WeakPolarHBondContact CG2-OH 3.16Å
192R91.6Very high91.1Very high112 Ų11258.7 Ų58.742%0.42332%0.318SS..Hα-helixtrans-57.2-45.6177.1-170.9-170.373.179.24.1111.3K188 E189 K190 Q195 L196K188-R192 WeakPolarHBondContact O-CB 3.4Å; K188-R192 PolarHBondContact O-N 3.38Å; E189-R192 WeakPolarHBondContact O-CB 3.39Å; E189-R192 PolarHBondContact O-N 3.37Å; E189-R192 IonicContact OE1-CZ 3.59Å; E189-R192 IonicContact OE1-NE 2.9Å; E189-R192 PolarHBondContact OE1-NE 3.44Å; E189-R192 IonicContact OE1-NH2 2.77Å; E189-R192 PolarHBondContact OE1-NH2 3.12Å; E189-R192 IonicContact OE2-CZ 3.66Å; E189-R192 IonicContact OE2-NE 2.79Å; E189-R192 PolarHBondContact OE2-NE 2.94Å; E189-R192 IonicContact OE2-NH2 2.87Å; K190-R192 PolarHBondContact O-N 3.18Å; R192-Q195 PolarHBondContact O-N 3.37Å; R192-L196 WeakPolarHBondContact O-CG 3.38Å; R192-L196 PolarHBondContact O-N 3.01Å
193I93.6Very high91.2Very high22 Ų2261 Ų6111%0.11332%0.323CS..Hα-helixtrans-65.7-40.5178.9-65.4169.1000111E189 K190 V191 Q195 L196 Y197 V202 L207 S210E189-I193 HydrophobicContact CG-CD1 4.18Å; E189-I193 WeakPolarHBondContact O-CG1 3.35Å; E189-I193 PolarHBondContact O-N 3.17Å; K190-I193 PolarHBondContact O-N 3.46Å; V191-I193 VanDerWaalsContact C-N 3.31Å; V191-I193 PolarHBondContact O-N 3.12Å; I193-Q195 PolarHBondContact O-N 3.15Å; I193-L196 PolarHBondContact O-N 2.68Å; I193-Y197 WeakPolarHBondContact O-CB 3.4Å; I193-Y197 PolarHBondContact O-N 2.89Å; I193-V202 HydrophobicContact CG2-CG2 4.42Å; I193-L207 HydrophobicContact CG2-CD1 4.29Å; I193-S210 VanDerWaalsContact CD1-CB 3.46Å
194R91.5Very high91.3Very high41 Ų4166 Ų6616%0.15533%0.332CS..Hα-helixtrans-59.6-43.1173-72.8174.9178.9-165.3-5.9112.9K190 V191 Y197 A198 L207 E211 H488K190-R194 WeakPolarHBondContact O-CG 3.35Å; K190-R194 PolarHBondContact O-N 3.1Å; V191-R194 WeakPolarHBondContact O-CB 3.48Å; V191-R194 PolarHBondContact O-N 3.43Å; R194-Y197 PolarHBondContact O-N 3.3Å; R194-A198 PolarHBondContact O-N 3.47Å; R194-L207 HydrophobicContact CG-CD1 3.81Å; R194-E211 IonicContact CZ-OE1 3.33Å; R194-E211 IonicContact CZ-OE2 3.87Å; R194-E211 IonicContact NE-OE1 3.54Å; R194-E211 PolarHBondContact NE-OE1 3.28Å; R194-E211 IonicContact NH2-OE1 3.52Å; R194-E211 PolarHBondContact NH2-OE1 3.04Å; R194-E211 IonicContact NH2-OE2 3.52Å; R194-E211 PolarHBondContact NH2-OE2 3.21Å; R194-H488 PolarHBondContact NH1-CE1 3.26Å; R194-H488 VanDerWaalsContact NH1-CE1 3.27Å; R194-H488 PolarHBondContact NH1-NE2 3.45Å
195Q91.1Very high91.5Very high35 Ų3570.2 Ų70.216%0.16435%0.346CS..Hα-helixtrans-65.5-45.3177.1-71.5179.8-54.900111.2V191 R192 I193 Y197 A198 E199 V496 D499V191-Q195 HydrophobicContact CG1-CG 4.4Å; V191-Q195 WeakPolarHBondContact O-CG 3.43Å; V191-Q195 PolarHBondContact O-N 3.21Å; R192-Q195 PolarHBondContact O-N 3.37Å; I193-Q195 PolarHBondContact O-N 3.15Å; Q195-Y197 PolarHBondContact O-N 3.17Å; Q195-A198 PolarHBondContact O-N 2.97Å; Q195-A198 VanDerWaalsContact O-N 3.15Å; Q195-E199 WeakPolarHBondContact O-CG 3.27Å; Q195-E199 PolarHBondContact O-N 3.16Å; Q195-V496 HydrophobicContact CB-CG2 4.24Å; Q195-V496 HydrophobicContact CG-CG2 4.26Å; Q195-D499 PolarHBondContact NE2-OD2 3.48Å
196L94.1Very high91.7Very high35 Ų3570 Ų7018%0.18335%0.351CS..Hα-helixtrans-59.7-36.4175.1-71.8-179.9000112.4R192 I193 E199 G200 K201 V202R192-L196 WeakPolarHBondContact O-CG 3.38Å; R192-L196 PolarHBondContact O-N 3.01Å; I193-L196 PolarHBondContact O-N 2.68Å; L196-E199 CarbonylContact O-C 3.42Å; L196-E199 PolarHBondContact O-N 3.46Å; L196-G200 PolarHBondContact O-N 2.93Å; L196-K201 HydrophobicContact CB-CB 4.28Å; L196-K201 HydrophobicContact CD2-CB 4.06Å; L196-K201 HydrophobicContact CD2-CD 3.61Å; L196-K201 HydrophobicContact CD2-CG 4.49Å; L196-K201 PolarHBondContact O-N 3.38Å; L196-V202 HydrophobicContact CB-CG1 3.98Å; L196-V202 HydrophobicContact CB-CG2 3.87Å; L196-V202 HydrophobicContact CD1-CG1 4.05Å
197Y93.1Very high92Very high101 Ų10167.3 Ų67.340%0.39633%0.332SS..Hα-helixtrans-66.5-44.3176-179.7-101.4000111.1I193 R194 Q195 E199 G200 V202 R204 L207I193-Y197 WeakPolarHBondContact O-CB 3.4Å; I193-Y197 PolarHBondContact O-N 2.89Å; R194-Y197 PolarHBondContact O-N 3.3Å; Q195-Y197 PolarHBondContact O-N 3.17Å; Y197-E199 PolarHBondContact O-N 3.13Å; Y197-G200 PolarHBondContact O-N 3.26Å; Y197-V202 HydrophobicContact CD2-CG2 4.45Å; Y197-V202 WeakPolarHBondContact CD2-O 3.34Å; Y197-R204 HydrophobicContact CE2-CB 4.21Å; Y197-L207 HydrophobicContact CD1-CD2 3.58Å; Y197-L207 HydrophobicContact CD2-CB 4.19Å; Y197-L207 HydrophobicContact CD2-CD2 4.12Å; Y197-L207 HydrophobicContact CE1-CD2 3.85Å; Y197-L207 HydrophobicContact CE2-CD2 4.39Å; Y197-L207 HydrophobicContact CG-CB 4.32Å; Y197-L207 HydrophobicContact CG-CD2 3.72Å; Y197-L207 HydrophobicContact CG-CG 4.5Å
198A88.6Confident92.6Very high16 Ų1671 Ų7113%0.13235%0.352CS..Hα-helixtrans-62-29.7174.500000112.7R194 Q195 G200 M458 P492R194-A198 PolarHBondContact O-N 3.47Å; Q195-A198 PolarHBondContact O-N 2.97Å; Q195-A198 VanDerWaalsContact O-N 3.15Å; A198-G200 VanDerWaalsContact C-N 3.29Å; A198-M458 HydrophobicContact CB-CE 4.08Å; A198-M458 WeakPolarHBondContact O-CE 3.42Å; A198-P492 HydrophobicContact CB-CB 4.17Å
199E91.1Very high93.1Very high66 Ų6668.8 Ų68.831%0.30834%0.344SS..THydrogen-bonded Turntrans-82.4-0.1172.5-65.5-177.4107.200113.9Q195 L196 Y197 K201 V496Q195-E199 WeakPolarHBondContact O-CG 3.27Å; Q195-E199 PolarHBondContact O-N 3.16Å; L196-E199 CarbonylContact O-C 3.42Å; L196-E199 PolarHBondContact O-N 3.46Å; Y197-E199 PolarHBondContact O-N 3.13Å; E199-K201 VanDerWaalsContact C-N 3.26Å; E199-K201 HydrophobicContact CB-CD 4.02Å; E199-K201 HydrophobicContact CB-CG 4.05Å; E199-K201 PolarHBondContact O-N 2.79Å; E199-K201 IonicContact OE1-NZ 3.47Å; E199-K201 PolarHBondContact OE1-NZ 3.25Å; E199-K201 WeakPolarHBondContact OE2-CE 3.42Å; E199-K201 IonicContact OE2-NZ 2.8Å; E199-K201 PolarHBondContact OE2-NZ 3.48Å; E199-V496 HydrophobicContact CG-CG1 4.4Å; E199-V496 HydrophobicContact CG-CG2 4.28Å
200G92.4Very high93.3Very high64 Ų6466.1 Ų66.166%0.6633%0.332SS*.THydrogen-bonded Turntrans70.715.4-177.100000115L196 Y197 A198L196-G200 PolarHBondContact O-N 2.93Å; Y197-G200 PolarHBondContact O-N 3.26Å; A198-G200 VanDerWaalsContact C-N 3.29Å
201K95.7Very high93.4Very high130 Ų13067.5 Ų67.557%0.56534%0.338SS*.SBendtrans-89-16.2-175.9-66.4174.3-1741610114.2L196 E199L196-K201 HydrophobicContact CB-CB 4.28Å; L196-K201 HydrophobicContact CD2-CB 4.06Å; L196-K201 HydrophobicContact CD2-CD 3.61Å; L196-K201 HydrophobicContact CD2-CG 4.49Å; L196-K201 PolarHBondContact O-N 3.38Å; E199-K201 VanDerWaalsContact C-N 3.26Å; E199-K201 HydrophobicContact CB-CD 4.02Å; E199-K201 HydrophobicContact CB-CG 4.05Å; E199-K201 PolarHBondContact O-N 2.79Å; E199-K201 IonicContact OE1-NZ 3.47Å; E199-K201 PolarHBondContact OE1-NZ 3.25Å; E199-K201 WeakPolarHBondContact OE2-CE 3.42Å; E199-K201 IonicContact OE2-NZ 2.8Å; E199-K201 PolarHBondContact OE2-NZ 3.48Å
202V96.6Very high93.7Very high41 Ų4167.7 Ų67.725%0.24835%0.345CS..SBendtrans-130.8154.4171.9-62.40000109.5I193 L196 Y197 A206I193-V202 HydrophobicContact CG2-CG2 4.42Å; L196-V202 HydrophobicContact CB-CG1 3.98Å; L196-V202 HydrophobicContact CB-CG2 3.87Å; L196-V202 HydrophobicContact CD1-CG1 4.05Å; Y197-V202 HydrophobicContact CD2-CG2 4.45Å; Y197-V202 WeakPolarHBondContact CD2-O 3.34Å; V202-A206 HydrophobicContact CB-CB 4.1Å
203D96.7Very high93.7Very high98 Ų9864.2 Ų64.252%0.52434%0.34SS..  trans-85176.3179.771.518.2000112.7M205 A206 L207D203-M205 VanDerWaalsContact C-N 3.26Å; D203-M205 PolarHBondContact O-N 3.26Å; D203-M205 WeakPolarHBondContact OD1-CA 3.49Å; D203-M205 WeakPolarHBondContact OD1-CB 3.36Å; D203-M205 PolarHBondContact OD1-N 3.04Å; D203-A206 PolarHBondContact O-N 3.35Å; D203-A206 PolarHBondContact OD1-N 3.38Å; D203-L207 PolarHBondContact O-N 2.93Å
204R95.4Very high93.6Very high168 Ų16863.4 Ų63.463%0.63434%0.336SS*.Hα-helixtrans-64.1-29.9179-176.7177.8177.3-85.4-0.4112.6Y197 L208Y197-R204 HydrophobicContact CE2-CB 4.21Å; R204-L208 WeakPolarHBondContact O-CB 3.35Å; R204-L208 PolarHBondContact O-N 3.02Å
205M96.2Very high93.5Very high115 Ų11565.3 Ų65.357%0.56734%0.344SS*.Hα-helixtrans-72.5-43-178.6-73.3-56.7-57.100111.1D203 L207 L208 E209D203-M205 VanDerWaalsContact C-N 3.26Å; D203-M205 PolarHBondContact O-N 3.26Å; D203-M205 WeakPolarHBondContact OD1-CA 3.49Å; D203-M205 WeakPolarHBondContact OD1-CB 3.36Å; D203-M205 PolarHBondContact OD1-N 3.04Å; M205-L207 VanDerWaalsContact C-N 3.31Å; M205-L207 PolarHBondContact O-N 3.44Å; M205-L208 PolarHBondContact O-N 2.9Å; M205-E209 PolarHBondContact O-N 3.26Å
206A95.1Very high93.5Very high41 Ų4167.9 Ų67.934%0.33936%0.356SS..Hα-helixtrans-60.4-41.3173.600000112V202 D203 S210V202-A206 HydrophobicContact CB-CB 4.1Å; D203-A206 PolarHBondContact O-N 3.35Å; D203-A206 PolarHBondContact OD1-N 3.38Å; A206-S210 PolarHBondContact O-N 2.82Å
207L94Very high93.5Very high32 Ų3267.8 Ų67.817%0.16836%0.36CS..Hα-helixtrans-61.2-48.6173.6178.962.7000111.1I193 R194 Y197 D203 M205 E209 S210 E211I193-L207 HydrophobicContact CG2-CD1 4.29Å; R194-L207 HydrophobicContact CG-CD1 3.81Å; Y197-L207 HydrophobicContact CD1-CD2 3.58Å; Y197-L207 HydrophobicContact CD2-CB 4.19Å; Y197-L207 HydrophobicContact CD2-CD2 4.12Å; Y197-L207 HydrophobicContact CE1-CD2 3.85Å; Y197-L207 HydrophobicContact CE2-CD2 4.39Å; Y197-L207 HydrophobicContact CG-CB 4.32Å; Y197-L207 HydrophobicContact CG-CD2 3.72Å; Y197-L207 HydrophobicContact CG-CG 4.5Å; D203-L207 PolarHBondContact O-N 2.93Å; M205-L207 VanDerWaalsContact C-N 3.31Å; M205-L207 PolarHBondContact O-N 3.44Å; L207-E209 PolarHBondContact O-N 3Å; L207-S210 PolarHBondContact O-N 3.38Å; L207-S210 PolarHBondContact O-OG 3.15Å; L207-E211 HydrophobicContact CD1-CG 4.45Å; L207-E211 WeakPolarHBondContact O-CG 3.33Å; L207-E211 PolarHBondContact O-N 2.84Å; L207-E211 VanDerWaalsContact O-N 3.1Å
208L95.3Very high93.6Very high85 Ų8566 Ų6645%0.44536%0.361SS..Hα-helixtrans-60.5-44.7-179179.960.8000112.5R204 M205 S210 E211 A212R204-L208 WeakPolarHBondContact O-CB 3.35Å; R204-L208 PolarHBondContact O-N 3.02Å; M205-L208 PolarHBondContact O-N 2.9Å; L208-S210 VanDerWaalsContact C-N 3.28Å; L208-S210 PolarHBondContact O-N 3.37Å; L208-E211 PolarHBondContact O-N 3.4Å; L208-A212 WeakPolarHBondContact O-CB 3.34Å; L208-A212 PolarHBondContact O-N 2.98Å
209E95.7Very high93.9Very high131 Ų13165.2 Ų65.261%0.61236%0.355SS*.Hα-helixtrans-59.7-41177.8-169.762.5-14900111.2M205 L207 E211 A212 A213M205-E209 PolarHBondContact O-N 3.26Å; L207-E209 PolarHBondContact O-N 3Å; E209-E211 PolarHBondContact O-N 3.23Å; E209-A212 PolarHBondContact O-N 2.96Å; E209-A213 WeakPolarHBondContact O-CB 3.41Å; E209-A213 PolarHBondContact O-N 2.84Å
210S94.2Very high94.1Very high6 Ų662.1 Ų62.14%0.04234%0.34CS..Hα-helixtrans-65.3-37.2177.279.70000113.5L185 I193 A206 L207 L208 S214L185-S210 WeakPolarHBondContact CD2-O 3.32Å; I193-S210 VanDerWaalsContact CD1-CB 3.46Å; A206-S210 PolarHBondContact O-N 2.82Å; L207-S210 PolarHBondContact O-N 3.38Å; L207-S210 PolarHBondContact O-OG 3.15Å; L208-S210 VanDerWaalsContact C-N 3.28Å; L208-S210 PolarHBondContact O-N 3.37Å; S210-S214 PolarHBondContact O-N 2.77Å; S210-S214 PolarHBondContact O-OG 2.9Å
211E91.8Very high94Very high33 Ų3360.6 Ų60.615%0.15432%0.319CS..Hα-helixtrans-70.9-44.3176.1-63.1-68.9168.300110.6R194 L207 L208 E209 A213 S214 Y215R194-E211 IonicContact CZ-OE1 3.33Å; R194-E211 IonicContact CZ-OE2 3.87Å; R194-E211 IonicContact NE-OE1 3.54Å; R194-E211 PolarHBondContact NE-OE1 3.28Å; R194-E211 IonicContact NH2-OE1 3.52Å; R194-E211 PolarHBondContact NH2-OE1 3.04Å; R194-E211 IonicContact NH2-OE2 3.52Å; R194-E211 PolarHBondContact NH2-OE2 3.21Å; L207-E211 HydrophobicContact CD1-CG 4.45Å; L207-E211 WeakPolarHBondContact O-CG 3.33Å; L207-E211 PolarHBondContact O-N 2.84Å; L207-E211 VanDerWaalsContact O-N 3.1Å; L208-E211 PolarHBondContact O-N 3.4Å; E209-E211 PolarHBondContact O-N 3.23Å; E211-A213 PolarHBondContact O-N 3.12Å; E211-S214 WeakPolarHBondContact O-CA 3.31Å; E211-S214 WeakPolarHBondContact O-CB 3.3Å; E211-S214 PolarHBondContact O-N 2.85Å; E211-Y215 HydrophobicContact CB-CD2 4.5Å; E211-Y215 HydrophobicContact CB-CE2 4.36Å; E211-Y215 WeakPolarHBondContact O-CD2 3.38Å; E211-Y215 PolarHBondContact O-N 3.04Å; E211-Y215 VanDerWaalsContact OE2-CE2 3.23Å; E211-Y215 WeakPolarHBondContact OE2-CE2 3.35Å; E211-Y215 PolarHBondContact OE2-OH 2.64Å
212A93.1Very high93.8Very high50 Ų5054.9 Ų54.941%0.41330%0.295SS..Hα-helixtrans-61.9-41.7178.200000112L208 E209 S214 Y215 H216L208-A212 WeakPolarHBondContact O-CB 3.34Å; L208-A212 PolarHBondContact O-N 2.98Å; E209-A212 PolarHBondContact O-N 2.96Å; A212-S214 PolarHBondContact O-N 3.11Å; A212-Y215 CarbonylContact O-C 3.59Å; A212-Y215 PolarHBondContact O-N 2.84Å; A212-H216 PolarHBondContact O-N 3.13Å
213A93.3Very high93.4Very high38 Ų3854.4 Ų54.431%0.31429%0.29SS..THydrogen-bonded Turntrans-65.8-18.5173.700000113.4L185 E209 E211 H216L185-A213 HydrophobicContact CB-CB 4.11Å; L185-A213 PolarHBondContact N-O 3.39Å; L185-A213 VanDerWaalsContact N-O 3.12Å; E209-A213 WeakPolarHBondContact O-CB 3.41Å; E209-A213 PolarHBondContact O-N 2.84Å; E211-A213 PolarHBondContact O-N 3.12Å; A213-H216 PolarHBondContact O-CD2 2.85Å
214S89.7Confident93.2Very high6 Ų649.8 Ų49.84%0.04227%0.265CS..THydrogen-bonded Turntrans-88.4-31174.7-55.50000112.7K190 S210 E211 A212K190-S214 WeakPolarHBondContact CD-OG 3.44Å; S210-S214 PolarHBondContact O-N 2.77Å; S210-S214 PolarHBondContact O-OG 2.9Å; E211-S214 WeakPolarHBondContact O-CA 3.31Å; E211-S214 WeakPolarHBondContact O-CB 3.3Å; E211-S214 PolarHBondContact O-N 2.85Å; A212-S214 PolarHBondContact O-N 3.11Å
215Y90Very high92.9Very high81 Ų8141.9 Ų41.932%0.31824%0.236SC..SBendtrans-114.654.2-178.1-49.2-55.7000111K190 E211 A212 C221K190-Y215 PolarHBondContact NZ-OH 3.32Å; E211-Y215 HydrophobicContact CB-CD2 4.5Å; E211-Y215 HydrophobicContact CB-CE2 4.36Å; E211-Y215 WeakPolarHBondContact O-CD2 3.38Å; E211-Y215 PolarHBondContact O-N 3.04Å; E211-Y215 VanDerWaalsContact OE2-CE2 3.23Å; E211-Y215 WeakPolarHBondContact OE2-CE2 3.35Å; E211-Y215 PolarHBondContact OE2-OH 2.64Å; A212-Y215 CarbonylContact O-C 3.59Å; A212-Y215 PolarHBondContact O-N 2.84Å; Y215-C221 HydrophobicContact CE1-CB 4.46Å
216H91.9Very high92.7Very high89 Ų8936.8 Ų36.841%0.41221%0.211SC..  trans-86.7-8.4-166.162.858.9000115.1A182 G184 A212 A213A182-H216 PolarHBondContact O-NE2 2.84Å; G184-H216 VanDerWaalsContact CA-CD2 3.48Å; G184-H216 WeakPolarHBondContact CA-CD2 3.42Å; G184-H216 VanDerWaalsContact CA-NE2 3.33Å; G184-H216 WeakPolarHBondContact CA-NE2 3.32Å; G184-H216 PolarHBondContact N-NE2 2.86Å; A212-H216 PolarHBondContact O-N 3.13Å; A213-H216 PolarHBondContact O-CD2 2.85Å
217A94.2Very high92.6Very high32 Ų3235.7 Ų35.726%0.26420%0.202SC..SBendtrans-152165.2-17200000112.9M181M181-A217 HydrophobicContact CB-CB 4.31Å; M181-A217 WeakPolarHBondContact CE-O 3.46Å
218P95.2Very high92.6Very high64 Ų6434.2 Ų34.242%0.41619%0.194SC..SBendtrans-58.2150.9169.2-23.234.5000113P83 M181P83-P218 HydrophobicContact CG-CB 3.94Å; M181-P218 WeakPolarHBondContact CA-O 3.46Å; M181-P218 VanDerWaalsContact CB-O 3.31Å; M181-P218 WeakPolarHBondContact CB-O 3.25Å
219G94.9Very high92.6Very high0 Ų030.2 Ų30.20%017%0.173CC..SBendtrans117.8171.2-176.300000113.9S79 A80 G179 M181S79-G219 CarbonylContact C-O 3.1Å; S79-G219 PolarHBondContact O-N 3.39Å; S79-G219 PolarHBondContact OG-O 2.78Å; A80-G219 WeakPolarHBondContact CA-O 3.48Å; A80-G219 PolarHBondContact N-O 3.21Å; G179-G219 CarbonylContact O-C 3.5Å; G179-G219 VanDerWaalsContact O-CA 3.25Å; G179-G219 WeakPolarHBondContact O-CA 3.49Å; M181-G219 VanDerWaalsContact CE-O 3.26Å; M181-G219 WeakPolarHBondContact CE-O 3.32Å
220T93.9Very high92.6Very high1 Ų124 Ų241%0.00614%0.144CC..BIsolated β-bridgetrans-66.7154.5172.8620000111.1A80 V153 G179 P180 M181 A227 N228 Q231A80-T220 HydrophobicContact CB-CG2 3.88Å; V153-T220 HydrophobicContact CB-CG2 3.78Å; V153-T220 HydrophobicContact CG2-CG2 3.49Å; V153-T220 VanDerWaalsContact CG2-CG2 3.49Å; G179-T220 PolarHBondContact O-N 3Å; P180-T220 VanDerWaalsContact CA-OG1 3.22Å; P180-T220 WeakPolarHBondContact CA-OG1 3.47Å; M181-T220 WeakPolarHBondContact CG-O 3.39Å; M181-T220 PolarHBondContact N-O 3.23Å; T220-A227 HydrophobicContact CG2-CB 4.5Å; T220-N228 PolarHBondContact OG1-OD1 2.82Å; T220-Q231 PolarHBondContact OG1-NE2 3.05Å
221C90.1Very high92.6Very high32 Ų3223.8 Ų23.822%0.21614%0.143CC..  trans-54.2150.8172.5-52.20000110.7Y215 F223 N228Y215-C221 HydrophobicContact CE1-CB 4.46Å; C221-F223 HydrophobicContact CB-CD1 3.6Å; C221-F223 HydrophobicContact CB-CE1 3.46Å; C221-F223 VanDerWaalsContact CB-CE1 3.46Å; C221-F223 HydrophobicContact CB-CZ 4.4Å; C221-N228 PolarHBondContact O-ND2 3.31Å
222T91.8Very high92.8Very high9 Ų922.2 Ų22.26%0.05514%0.135CC..SBendtrans-81.5-20.7-176.361.80000113.9M181 A182 D343 I344M181-T222 HydrophobicContact CG-CG2 3.63Å; M181-T222 WeakPolarHBondContact O-CG2 3.43Å; A182-T222 WeakPolarHBondContact O-CG2 3.27Å; T222-D343 WeakPolarHBondContact O-CB 3.12Å; T222-I344 WeakPolarHBondContact O-CB 3.31Å; T222-I344 WeakPolarHBondContact O-CG2 3.41Å; T222-I344 PolarHBondContact O-N 3.11Å
223F89.6Confident93Very high32 Ų3219.8 Ų19.814%0.1412%0.116CC..SBendtrans-71.5157.1177.370.3-87.1000112.8C221 G225 N228 Y337 A515C221-F223 HydrophobicContact CB-CD1 3.6Å; C221-F223 HydrophobicContact CB-CE1 3.46Å; C221-F223 VanDerWaalsContact CB-CE1 3.46Å; C221-F223 HydrophobicContact CB-CZ 4.4Å; F223-G225 PolarHBondContact O-N 3.36Å; F223-N228 PolarHBondContact O-ND2 2.8Å; F223-Y337 HydrophobicContact CB-CD1 3.33Å; F223-Y337 HydrophobicContact CB-CE1 3.71Å; F223-Y337 HydrophobicContact CG-CD1 4.31Å; F223-Y337 HydrophobicContact CG-CE1 4.23Å; F223-A515 HydrophobicContact CD2-CB 3.88Å; F223-A515 HydrophobicContact CE2-CB 3.7Å
224Y91.4Very high93.2Very high0 Ų018.2 Ų18.20%010%0.102CC..SBendtrans-82.260.7177.3-162.5-127.1000112.5N228 M232 T297 L336 Y337 I344Y224-N228 HydrophobicContact CD2-CB 3.79Å; Y224-N228 HydrophobicContact CE2-CB 4.21Å; Y224-M232 HydrophobicContact CE2-CB 4.31Å; Y224-M232 HydrophobicContact CE2-CG 3.66Å; Y224-M232 WeakPolarHBondContact OH-CB 3.38Å; Y224-M232 WeakPolarHBondContact OH-CG 3.46Å; Y224-T297 VanDerWaalsContact CE1-CB 3.5Å; Y224-T297 VanDerWaalsContact CE1-O 3.3Å; Y224-T297 WeakPolarHBondContact CE1-O 3.48Å; Y224-T297 WeakPolarHBondContact CE1-OG1 3.26Å; Y224-T297 WeakPolarHBondContact OH-CB 3.49Å; Y224-T297 PolarHBondContact OH-OG1 2.95Å; Y224-L336 HydrophobicContact CD1-CB 4.32Å; Y224-L336 HydrophobicContact CD1-CD1 4.13Å; Y224-L336 HydrophobicContact CD2-CD1 3.83Å; Y224-L336 HydrophobicContact CE2-CD1 4.38Å; Y224-L336 HydrophobicContact CG-CB 4.04Å; Y224-L336 HydrophobicContact CG-CD1 3.73Å; Y224-L336 HydrophobicContact CG-CG 4.48Å; Y224-Y337 WeakPolarHBondContact CA-O 3.41Å; Y224-Y337 WeakPolarHBondContact CB-O 3.35Å; Y224-Y337 PolarHBondContact N-O 3.24Å; Y224-I344 HydrophobicContact CD2-CD1 4.1Å
225G89.8Confident93.6Very high3 Ų318 Ų183%0.03110%0.1CC..SBendtrans-83.8-173.4168.200000111.9F223 A227 N228 T229F223-G225 PolarHBondContact O-N 3.36Å; G225-A227 VanDerWaalsContact C-N 3.29Å; G225-A227 PolarHBondContact O-N 3Å; G225-N228 PolarHBondContact O-N 3.07Å; G225-N228 VanDerWaalsContact O-N 3.16Å; G225-T229 PolarHBondContact O-N 3.26Å; G225-T229 PolarHBondContact O-OG1 2.73Å; G225-T229 VanDerWaalsContact O-OG1 3.05Å
226T91.4Very high94Very high7 Ų714.1 Ų14.14%0.0439%0.085CC..Hα-helixtrans-61.4-33.8-173.4-36.60000113.8D155 T229 N230 S300 N302 H303D155-T226 HydrophobicContact CB-CG2 4.08Å; D155-T226 WeakPolarHBondContact OD1-CG2 3.4Å; D155-T226 WeakPolarHBondContact OD2-CB 3.39Å; D155-T226 VanDerWaalsContact OD2-CG2 3.22Å; D155-T226 WeakPolarHBondContact OD2-CG2 3.44Å; D155-T226 PolarHBondContact OD2-OG1 3.49Å; T226-T229 PolarHBondContact O-N 3.32Å; T226-N230 WeakPolarHBondContact O-CB 2.9Å; T226-N230 PolarHBondContact O-N 3.01Å; T226-N230 PolarHBondContact O-ND2 3.38Å; T226-S300 WeakPolarHBondContact OG1-CB 3.2Å; T226-S300 PolarHBondContact OG1-OG 3.08Å; T226-N302 HydrophobicContact CG2-CB 3.85Å; T226-N302 PolarHBondContact OG1-ND2 3.17Å; T226-H303 VanDerWaalsContact CG2-CE1 3.46Å; T226-H303 WeakPolarHBondContact CG2-CE1 3.22Å
227A92.8Very high94.3Very high18 Ų1810.1 Ų10.115%0.1497%0.067CC..Hα-helixtrans-61.3-46.3176.400000112T220 G225 N230 Q231T220-A227 HydrophobicContact CG2-CB 4.5Å; G225-A227 VanDerWaalsContact C-N 3.29Å; G225-A227 PolarHBondContact O-N 3Å; A227-N230 WeakPolarHBondContact O-CB 3.27Å; A227-N230 PolarHBondContact O-N 3.37Å; A227-Q231 WeakPolarHBondContact O-CG 3.44Å; A227-Q231 PolarHBondContact O-N 3.11Å; A227-Q231 VanDerWaalsContact O-N 3.16Å
228N94.5Very high94.5Very high2 Ų28.6 Ų8.61%0.0115%0.054CC..Hα-helixtrans-76.1-29177.1-70.2-22000112.5T220 C221 F223 Y224 G225 N230 Q231 M232 I344T220-N228 PolarHBondContact OG1-OD1 2.82Å; C221-N228 PolarHBondContact O-ND2 3.31Å; F223-N228 PolarHBondContact O-ND2 2.8Å; Y224-N228 HydrophobicContact CD2-CB 3.79Å; Y224-N228 HydrophobicContact CE2-CB 4.21Å; G225-N228 PolarHBondContact O-N 3.07Å; G225-N228 VanDerWaalsContact O-N 3.16Å; N228-N230 VanDerWaalsContact C-N 3.33Å; N228-Q231 PolarHBondContact O-N 3.47Å; N228-Q231 PolarHBondContact OD1-NE2 2.9Å; N228-M232 PolarHBondContact O-N 2.86Å; N228-I344 HydrophobicContact CB-CD1 4.42Å; N228-I344 HydrophobicContact CB-CG1 4.41Å
229T95Very high94.7Very high0 Ų05.6 Ų5.60%03%0.034CC..Hα-helixtrans-61.3-42.9168.2-52.50000111G225 T226 Q231 M232 V233 L294 S300 H303G225-T229 PolarHBondContact O-N 3.26Å; G225-T229 PolarHBondContact O-OG1 2.73Å; G225-T229 VanDerWaalsContact O-OG1 3.05Å; T226-T229 PolarHBondContact O-N 3.32Å; T229-Q231 VanDerWaalsContact C-N 3.35Å; T229-Q231 PolarHBondContact O-N 3.32Å; T229-M232 WeakPolarHBondContact O-CB 3.49Å; T229-M232 PolarHBondContact O-N 3.38Å; T229-V233 HydrophobicContact CG2-CG2 4.08Å; T229-V233 WeakPolarHBondContact O-CB 3.41Å; T229-V233 VanDerWaalsContact O-CG2 3.24Å; T229-V233 WeakPolarHBondContact O-CG2 3.29Å; T229-V233 PolarHBondContact O-N 2.99Å; T229-L294 HydrophobicContact CG2-CD1 3.64Å; T229-S300 PolarHBondContact OG1-N 3.3Å; T229-S300 VanDerWaalsContact OG1-N 3.09Å; T229-H303 VanDerWaalsContact CB-CE1 3.48Å; T229-H303 WeakPolarHBondContact CB-CE1 3.08Å; T229-H303 VanDerWaalsContact CG2-CE1 3.41Å; T229-H303 WeakPolarHBondContact CG2-CE1 3.45Å
230N95Very high94.9Very high0 Ų05.9 Ų5.90%04%0.036CC..Hα-helixtrans-58-48.3175.4-83.1-33.7000110.6C154 D155 V158 T226 A227 N228 M232 V233 V234 H303C154-N230 PolarHBondContact O-ND2 3.25Å; D155-N230 WeakPolarHBondContact CA-ND2 3.43Å; D155-N230 PolarHBondContact O-ND2 2.79Å; V158-N230 HydrophobicContact CB-CB 3.96Å; V158-N230 HydrophobicContact CG1-CB 4.01Å; V158-N230 HydrophobicContact CG2-CB 4.08Å; T226-N230 WeakPolarHBondContact O-CB 2.9Å; T226-N230 PolarHBondContact O-N 3.01Å; T226-N230 PolarHBondContact O-ND2 3.38Å; A227-N230 WeakPolarHBondContact O-CB 3.27Å; A227-N230 PolarHBondContact O-N 3.37Å; N228-N230 VanDerWaalsContact C-N 3.33Å; N230-M232 PolarHBondContact O-N 2.78Å; N230-V233 PolarHBondContact O-N 2.97Å; N230-V234 VanDerWaalsContact O-CB 3.32Å; N230-V234 WeakPolarHBondContact O-CB 3.45Å; N230-V234 VanDerWaalsContact O-CG2 3.26Å; N230-V234 WeakPolarHBondContact O-CG2 3.49Å; N230-V234 PolarHBondContact O-N 3.27Å; N230-H303 WeakPolarHBondContact CA-NE2 3.46Å; N230-H303 PolarHBondContact N-NE2 3.25Å; N230-H303 PolarHBondContact OD1-CE1 3.19Å; N230-H303 PolarHBondContact OD1-NE2 3.13Å
231Q95.4Very high95.1Very high2 Ų26.3 Ų6.31%0.0094%0.038CC..Hα-helixtrans-58.3-48.5179.1-68-171.8105.700111.6V153 T220 A227 N228 T229 V233 E235 S245 F246V153-Q231 HydrophobicContact CG1-CG 4.32Å; T220-Q231 PolarHBondContact OG1-NE2 3.05Å; A227-Q231 WeakPolarHBondContact O-CG 3.44Å; A227-Q231 PolarHBondContact O-N 3.11Å; A227-Q231 VanDerWaalsContact O-N 3.16Å; N228-Q231 PolarHBondContact O-N 3.47Å; N228-Q231 PolarHBondContact OD1-NE2 2.9Å; T229-Q231 VanDerWaalsContact C-N 3.35Å; T229-Q231 PolarHBondContact O-N 3.32Å; Q231-V233 PolarHBondContact O-N 3.17Å; Q231-E235 WeakPolarHBondContact O-CB 3.46Å; Q231-E235 PolarHBondContact O-N 3.22Å; Q231-S245 PolarHBondContact O-OG 3.17Å; Q231-S245 VanDerWaalsContact O-OG 3.12Å; Q231-S245 PolarHBondContact OE1-O 3.16Å; Q231-S245 VanDerWaalsContact OE1-O 3.09Å; Q231-F246 HydrophobicContact CB-CE1 4.06Å; Q231-F246 HydrophobicContact CB-CZ 4.22Å
232M96.1Very high95.5Very high0 Ų05 Ų50%03%0.029CC..Hα-helixtrans-55.3-50.3173.1-85.4-60.5-50.500112.7Y224 N228 T229 N230 E235 F236 F246 T297 F347 V353 L356Y224-M232 HydrophobicContact CE2-CB 4.31Å; Y224-M232 HydrophobicContact CE2-CG 3.66Å; Y224-M232 WeakPolarHBondContact OH-CB 3.38Å; Y224-M232 WeakPolarHBondContact OH-CG 3.46Å; N228-M232 PolarHBondContact O-N 2.86Å; T229-M232 WeakPolarHBondContact O-CB 3.49Å; T229-M232 PolarHBondContact O-N 3.38Å; N230-M232 PolarHBondContact O-N 2.78Å; M232-E235 PolarHBondContact O-N 2.79Å; M232-F236 HydrophobicContact CE-CD2 3.82Å; M232-F236 HydrophobicContact CE-CE2 3.3Å; M232-F236 HydrophobicContact CE-CZ 4.02Å; M232-F236 WeakPolarHBondContact O-CD2 3.41Å; M232-F236 PolarHBondContact O-N 3.31Å; M232-F246 HydrophobicContact CG-CE2 4.23Å; M232-F246 HydrophobicContact CG-CZ 3.81Å; M232-F246 HydrophobicContact SD-CE2 3.64Å; M232-F246 HydrophobicContact SD-CZ 3.87Å; M232-T297 HydrophobicContact CE-CG2 3.79Å; M232-F347 HydrophobicContact SD-CE1 3.77Å; M232-F347 HydrophobicContact SD-CZ 4.01Å; M232-V353 HydrophobicContact CE-CG2 4.12Å; M232-V353 HydrophobicContact SD-CG2 3.6Å; M232-V353 VanDerWaalsContact SD-CG2 3.6Å; M232-L356 HydrophobicContact CE-CD1 3.97Å
233V97.5Very high95.8Very high0 Ų04.7 Ų4.70%03%0.028CC..Hα-helixtrans-66.7-45.5-174.7166.60000111T229 N230 Q231 E235 F236 M237 A293 L294 L307T229-V233 HydrophobicContact CG2-CG2 4.08Å; T229-V233 WeakPolarHBondContact O-CB 3.41Å; T229-V233 VanDerWaalsContact O-CG2 3.24Å; T229-V233 WeakPolarHBondContact O-CG2 3.29Å; T229-V233 PolarHBondContact O-N 2.99Å; N230-V233 PolarHBondContact O-N 2.97Å; Q231-V233 PolarHBondContact O-N 3.17Å; V233-E235 VanDerWaalsContact C-N 3.29Å; V233-E235 PolarHBondContact O-N 2.83Å; V233-F236 PolarHBondContact O-N 3.15Å; V233-M237 HydrophobicContact CG1-CG 4.36Å; V233-M237 HydrophobicContact CG1-SD 3.74Å; V233-M237 WeakPolarHBondContact O-CB 3.19Å; V233-M237 VanDerWaalsContact O-CG 3.22Å; V233-M237 WeakPolarHBondContact O-CG 3.39Å; V233-M237 PolarHBondContact O-N 3.18Å; V233-A293 HydrophobicContact CG2-CB 4.32Å; V233-L294 HydrophobicContact CG2-CB 4.33Å; V233-L307 HydrophobicContact CG1-CD2 3.93Å
234V97.5Very high96.2Very high4 Ų43.4 Ų3.42%0.0242%0.023CC..Hα-helixtrans-64.1-35.4178.4170.80000111.4V158 F175 N230 M237 G238 M239 Q240V158-V234 HydrophobicContact CG1-CG2 3.44Å; V158-V234 VanDerWaalsContact CG1-CG2 3.44Å; F175-V234 HydrophobicContact CB-CG1 3.96Å; F175-V234 HydrophobicContact CD1-CG1 4.49Å; F175-V234 HydrophobicContact CG-CG1 4.17Å; N230-V234 VanDerWaalsContact O-CB 3.32Å; N230-V234 WeakPolarHBondContact O-CB 3.45Å; N230-V234 VanDerWaalsContact O-CG2 3.26Å; N230-V234 WeakPolarHBondContact O-CG2 3.49Å; N230-V234 PolarHBondContact O-N 3.27Å; V234-M237 PolarHBondContact O-N 3.39Å; V234-G238 PolarHBondContact O-N 3.49Å; V234-M239 HydrophobicContact CG1-CB 3.55Å; V234-M239 PolarHBondContact O-N 3.36Å; V234-Q240 HydrophobicContact CG1-CB 4.34Å; V234-Q240 HydrophobicContact CG1-CG 4.05Å
235E98.1Very high96.5Very high1 Ų13.4 Ų3.41%0.0052%0.023CC..Hα-helixtrans-67.2-44.4174.1-166.4161.616700112Q231 M232 V233 M237 G238 Q240 G243 S245 V353 Y381Q231-E235 WeakPolarHBondContact O-CB 3.46Å; Q231-E235 PolarHBondContact O-N 3.22Å; M232-E235 PolarHBondContact O-N 2.79Å; V233-E235 VanDerWaalsContact C-N 3.29Å; V233-E235 PolarHBondContact O-N 2.83Å; E235-M237 VanDerWaalsContact C-N 3.28Å; E235-M237 PolarHBondContact O-N 3.46Å; E235-G238 WeakPolarHBondContact O-CA 3.26Å; E235-G238 PolarHBondContact O-N 3.13Å; E235-Q240 HydrophobicContact CB-CG 4.05Å; E235-Q240 HydrophobicContact CG-CG 4.32Å; E235-Q240 PolarHBondContact OE2-NE2 3.04Å; E235-G243 VanDerWaalsContact OE1-CA 3.22Å; E235-G243 WeakPolarHBondContact OE1-CA 3.37Å; E235-G243 PolarHBondContact OE1-N 2.94Å; E235-S245 WeakPolarHBondContact OE2-CB 3.31Å; E235-S245 PolarHBondContact OE2-N 2.7Å; E235-S245 PolarHBondContact OE2-OG 3.03Å; E235-V353 HydrophobicContact CG-CG1 4.19Å; E235-Y381 HydrophobicContact CG-CD1 3.61Å; E235-Y381 HydrophobicContact CG-CE1 3.82Å; E235-Y381 WeakPolarHBondContact O-CD1 3.24Å; E235-Y381 VanDerWaalsContact O-CE1 3.23Å; E235-Y381 WeakPolarHBondContact O-CE1 2.93Å
236F98.1Very high96.8Very high1 Ų13.6 Ų3.60%0.0042%0.023CC..Hα-helixtrans-67.3-28174.5-89.8-121.8000113.6M232 V233 G238 A293 V353 L356 V357 L360 L366 L378M232-F236 HydrophobicContact CE-CD2 3.82Å; M232-F236 HydrophobicContact CE-CE2 3.3Å; M232-F236 HydrophobicContact CE-CZ 4.02Å; M232-F236 WeakPolarHBondContact O-CD2 3.41Å; M232-F236 PolarHBondContact O-N 3.31Å; V233-F236 PolarHBondContact O-N 3.15Å; F236-G238 PolarHBondContact O-N 3.12Å; F236-A293 HydrophobicContact CB-CB 3.55Å; F236-A293 HydrophobicContact CD1-CB 3.4Å; F236-A293 HydrophobicContact CD2-CB 4.05Å; F236-A293 HydrophobicContact CE1-CB 4.03Å; F236-A293 HydrophobicContact CG-CB 3.4Å; F236-V353 HydrophobicContact CD2-CG1 4.39Å; F236-V353 HydrophobicContact CE2-CG1 3.9Å; F236-L356 HydrophobicContact CZ-CB 4Å; F236-V357 HydrophobicContact CD2-CG2 4.22Å; F236-V357 HydrophobicContact CE1-CG2 4.05Å; F236-V357 HydrophobicContact CE2-CG2 3.62Å; F236-V357 HydrophobicContact CZ-CG2 3.52Å; F236-L360 HydrophobicContact CE1-CD1 3.7Å; F236-L360 HydrophobicContact CZ-CD1 4.21Å; F236-L366 HydrophobicContact CD1-CD1 4.14Å; F236-L366 HydrophobicContact CD1-CD2 3.93Å; F236-L366 HydrophobicContact CE1-CD1 3.82Å; F236-L366 HydrophobicContact CE1-CD2 4.22Å; F236-L378 WeakPolarHBondContact O-CD1 3.33Å
237M98.7Very high97.1Very high5 Ų54.1 Ų4.13%0.0253%0.026CC..THydrogen-bonded Turntrans-77.3-2.7171.5-70.7177.469.200112.5V233 V234 E235 M239 I282 V286 L307V233-M237 HydrophobicContact CG1-CG 4.36Å; V233-M237 HydrophobicContact CG1-SD 3.74Å; V233-M237 WeakPolarHBondContact O-CB 3.19Å; V233-M237 VanDerWaalsContact O-CG 3.22Å; V233-M237 WeakPolarHBondContact O-CG 3.39Å; V233-M237 PolarHBondContact O-N 3.18Å; V234-M237 PolarHBondContact O-N 3.39Å; E235-M237 VanDerWaalsContact C-N 3.28Å; E235-M237 PolarHBondContact O-N 3.46Å; M237-M239 VanDerWaalsContact C-N 3.31Å; M237-M239 HydrophobicContact CB-CG 4.1Å; M237-M239 HydrophobicContact CB-SD 4.03Å; M237-M239 HydrophobicContact CE-SD 3.92Å; M237-M239 PolarHBondContact O-N 3.22Å; M237-M239 HydrophobicContact SD-SD 4.39Å; M237-I282 HydrophobicContact CE-CD1 4.18Å; M237-I282 HydrophobicContact CE-CG2 4.34Å; M237-V286 HydrophobicContact CB-CG1 3.75Å; M237-V286 HydrophobicContact CE-CG1 4.22Å; M237-V286 HydrophobicContact CG-CG1 4.04Å; M237-V286 VanDerWaalsContact O-CG1 3.25Å; M237-V286 WeakPolarHBondContact O-CG1 3.44Å; M237-L307 HydrophobicContact SD-CD2 4.11Å
238G98.4Very high97.3Very high0 Ų06.1 Ų6.10%03%0.032CC..THydrogen-bonded Turntrans70.225.2176.300000114.3V234 E235 F236 V373 Y381V234-G238 PolarHBondContact O-N 3.49Å; E235-G238 WeakPolarHBondContact O-CA 3.26Å; E235-G238 PolarHBondContact O-N 3.13Å; F236-G238 PolarHBondContact O-N 3.12Å; G238-V373 WeakPolarHBondContact O-CG1 3.19Å; G238-V373 WeakPolarHBondContact O-CG2 3.27Å; G238-V373 PolarHBondContact O-N 3.1Å; G238-Y381 WeakPolarHBondContact CA-OH 3.44Å; G238-Y381 PolarHBondContact O-OH 2.98Å
239M98.6Very high97.4Very high1 Ų17 Ų71%0.0054%0.038CC..  trans-93-8.5-173.1-71.9174.960.600114.4T162 F175 V234 M237 I278 M281 I282T162-M239 HydrophobicContact CG2-CE 3.92Å; F175-M239 HydrophobicContact CD2-CB 4.27Å; F175-M239 HydrophobicContact CD2-CE 3.5Å; F175-M239 VanDerWaalsContact CD2-CE 3.5Å; F175-M239 HydrophobicContact CE1-CE 4.38Å; F175-M239 HydrophobicContact CE2-CE 3.17Å; F175-M239 HydrophobicContact CG-CE 4.26Å; F175-M239 HydrophobicContact CZ-CE 3.67Å; F175-M239 PolarHBondContact N-O 2.96Å; V234-M239 HydrophobicContact CG1-CB 3.55Å; V234-M239 PolarHBondContact O-N 3.36Å; M237-M239 VanDerWaalsContact C-N 3.31Å; M237-M239 HydrophobicContact CB-CG 4.1Å; M237-M239 HydrophobicContact CB-SD 4.03Å; M237-M239 HydrophobicContact CE-SD 3.92Å; M237-M239 PolarHBondContact O-N 3.22Å; M237-M239 HydrophobicContact SD-SD 4.39Å; M239-I278 HydrophobicContact CE-CD1 4.01Å; M239-M281 HydrophobicContact CB-CE 4.34Å; M239-M281 HydrophobicContact CG-CE 3.72Å; M239-I282 HydrophobicContact CG-CD1 3.65Å; M239-I282 HydrophobicContact SD-CD1 3.75Å
240Q98.4Very high97.3Very high5 Ų514 Ų142%0.0238%0.075CC..SBendtrans-137.6162.6178.660.317856.600109.6F175 V234 E235 S244 S245 V373 Y381F175-Q240 HydrophobicContact CB-CB 4.25Å; F175-Q240 VanDerWaalsContact O-CB 3.26Å; F175-Q240 WeakPolarHBondContact O-CB 3.16Å; V234-Q240 HydrophobicContact CG1-CB 4.34Å; V234-Q240 HydrophobicContact CG1-CG 4.05Å; E235-Q240 HydrophobicContact CB-CG 4.05Å; E235-Q240 HydrophobicContact CG-CG 4.32Å; E235-Q240 PolarHBondContact OE2-NE2 3.04Å; Q240-S244 PolarHBondContact NE2-OG 2.88Å; Q240-S245 PolarHBondContact NE2-OG 3.14Å; Q240-V373 VanDerWaalsContact O-CG2 3.3Å; Q240-V373 WeakPolarHBondContact O-CG2 3.38Å; Q240-Y381 VanDerWaalsContact O-CE1 3.32Å; Q240-Y381 WeakPolarHBondContact O-CE1 3.4Å; Q240-Y381 PolarHBondContact O-OH 3.26Å
241L98.6Very high97.4Very high10 Ų1015.7 Ų15.75%0.0529%0.087CC..  trans-62.4146.7-176.3-68.3176.5000112.4G243 S244 L257 A260 A261 Q264 V373 W394L241-G243 PolarHBondContact O-N 2.79Å; L241-S244 PolarHBondContact N-OG 2.83Å; L241-S244 WeakPolarHBondContact O-CB 3.48Å; L241-S244 PolarHBondContact O-N 2.94Å; L241-S244 VanDerWaalsContact O-N 3.09Å; L241-S244 PolarHBondContact O-OG 2.8Å; L241-L257 HydrophobicContact CB-CD2 4.4Å; L241-L257 HydrophobicContact CD1-CD2 4.23Å; L241-A260 HydrophobicContact CD1-CB 3.77Å; L241-A261 HydrophobicContact CD1-CB 4.07Å; L241-Q264 HydrophobicContact CD2-CB 4.27Å; L241-Q264 HydrophobicContact CD2-CG 4.09Å; L241-V373 HydrophobicContact CD2-CG2 4.44Å; L241-W394 HydrophobicContact CD1-CZ2 4.39Å
242P98.6Very high97.5Very high4 Ų419.8 Ų19.83%0.02611%0.114CC..THydrogen-bonded Turntrans-53.7131.3175.9-28.235.4000112.6S244 A374 Y381 P385 W394P242-S244 PolarHBondContact O-N 3.26Å; P242-A374 HydrophobicContact CG-CB 3.81Å; P242-Y381 HydrophobicContact CB-CD1 4.11Å; P242-Y381 HydrophobicContact CB-CE1 4.35Å; P242-Y381 HydrophobicContact CB-CG 4.43Å; P242-Y381 HydrophobicContact CG-CD1 4.09Å; P242-Y381 HydrophobicContact CG-CD2 4.34Å; P242-Y381 HydrophobicContact CG-CE1 3.97Å; P242-Y381 HydrophobicContact CG-CE2 4.19Å; P242-Y381 HydrophobicContact CG-CG 4.28Å; P242-P385 WeakPolarHBondContact O-CD 3.39Å; P242-W394 PolarHBondContact O-NE1 3.34Å
243G97.9Very high97.6Very high4 Ų421 Ų214%0.04112%0.12CC..THydrogen-bonded Turntrans68.612.9-179.500000114.7E235 L241E235-G243 VanDerWaalsContact OE1-CA 3.22Å; E235-G243 WeakPolarHBondContact OE1-CA 3.37Å; E235-G243 PolarHBondContact OE1-N 2.94Å; L241-G243 PolarHBondContact O-N 2.79Å
244S98.1Very high97.6Very high4 Ų421 Ų213%0.02812%0.12CC..  trans-83.2-18.1-175.468.10000114.6P177 Q240 L241 P242 F246 R254P177-S244 VanDerWaalsContact CG-O 3.27Å; P177-S244 WeakPolarHBondContact CG-O 3.49Å; Q240-S244 PolarHBondContact NE2-OG 2.88Å; L241-S244 PolarHBondContact N-OG 2.83Å; L241-S244 WeakPolarHBondContact O-CB 3.48Å; L241-S244 PolarHBondContact O-N 2.94Å; L241-S244 VanDerWaalsContact O-N 3.09Å; L241-S244 PolarHBondContact O-OG 2.8Å; P242-S244 PolarHBondContact O-N 3.26Å; S244-F246 PolarHBondContact O-N 2.7Å; S244-R254 PolarHBondContact O-NH1 3.07Å; S244-R254 VanDerWaalsContact O-NH1 3.1Å; S244-R254 PolarHBondContact O-NH2 3.1Å
245S97.4Very high97.7Very high0 Ų024.5 Ų24.50%014%0.139CC..THydrogen-bonded Turntrans-57.4-49.4-177.2-73.90000112.9G179 Q231 E235 Q240G179-S245 WeakPolarHBondContact CA-O 3.25Å; Q231-S245 PolarHBondContact O-OG 3.17Å; Q231-S245 VanDerWaalsContact O-OG 3.12Å; Q231-S245 PolarHBondContact OE1-O 3.16Å; Q231-S245 VanDerWaalsContact OE1-O 3.09Å; E235-S245 WeakPolarHBondContact OE2-CB 3.31Å; E235-S245 PolarHBondContact OE2-N 2.7Å; E235-S245 PolarHBondContact OE2-OG 3.03Å; Q240-S245 PolarHBondContact NE2-OG 3.14Å
246F97Very high97.7Very high8 Ų825.5 Ų25.54%0.03515%0.147CC..THydrogen-bonded Turntrans-109.517.2-161-53.5-57.8000113.9P180 Q231 M232 S244 I344 F347 Q348 V353P180-F246 HydrophobicContact CG-CB 4.42Å; P180-F246 HydrophobicContact CG-CD1 4.33Å; Q231-F246 HydrophobicContact CB-CE1 4.06Å; Q231-F246 HydrophobicContact CB-CZ 4.22Å; M232-F246 HydrophobicContact CG-CE2 4.23Å; M232-F246 HydrophobicContact CG-CZ 3.81Å; M232-F246 HydrophobicContact SD-CE2 3.64Å; M232-F246 HydrophobicContact SD-CZ 3.87Å; S244-F246 PolarHBondContact O-N 2.7Å; F246-I344 HydrophobicContact CD1-CD1 4.16Å; F246-I344 HydrophobicContact CD1-CG1 3.38Å; F246-I344 HydrophobicContact CE1-CD1 3.66Å; F246-I344 HydrophobicContact CE1-CG1 3.31Å; F246-I344 HydrophobicContact CE2-CD1 4.28Å; F246-I344 HydrophobicContact CE2-CG1 4.49Å; F246-I344 HydrophobicContact CG-CG1 4.07Å; F246-I344 HydrophobicContact CZ-CD1 3.75Å; F246-I344 HydrophobicContact CZ-CG1 3.92Å; F246-F347 HydrophobicContact CD2-CD1 4.46Å; F246-F347 HydrophobicContact CD2-CE1 4.36Å; F246-F347 HydrophobicContact CE2-CD1 4.36Å; F246-F347 HydrophobicContact CE2-CE1 4.03Å; F246-Q348 HydrophobicContact CB-CB 4.23Å; F246-Q348 HydrophobicContact CB-CG 4.09Å; F246-V353 HydrophobicContact CD2-CG2 4.29Å; F246-V353 HydrophobicContact CE2-CG2 3.82Å
247V97.5Very high97.7Very high17 Ų1725.6 Ų25.610%0.10315%0.147CC..SBendtrans-76.7126.5169.6-179.90000109.4G179 L253 R254 L257G179-V247 WeakPolarHBondContact CA-O 3.36Å; V247-L253 HydrophobicContact CG1-CB 3.93Å; V247-L253 HydrophobicContact CG1-CD2 4.14Å; V247-L253 HydrophobicContact CG1-CG 4.03Å; V247-L253 HydrophobicContact CG2-CD2 3.89Å; V247-L253 HydrophobicContact CG2-CG 4.29Å; V247-R254 HydrophobicContact CG1-CB 4.03Å; V247-R254 PolarHBondContact O-NH2 2.67Å; V247-L257 HydrophobicContact CB-CD1 4.21Å; V247-L257 HydrophobicContact CG1-CD1 4.49Å; V247-L257 HydrophobicContact CG2-CD1 3.68Å
248H97.1Very high97.7Very high61 Ų6125.3 Ų25.328%0.28215%0.146SC..  trans-59.5145.2-178.6-65.6-61000113P180 D250 S251 R254 N345P180-H248 PolarHBondContact O-ND1 3.46Å; H248-D250 VanDerWaalsContact C-N 3.25Å; H248-D250 WeakPolarHBondContact CB-OD1 3.48Å; H248-D250 PolarHBondContact O-N 3.29Å; H248-S251 WeakPolarHBondContact O-CB 3.34Å; H248-S251 PolarHBondContact O-N 3.42Å; H248-S251 VanDerWaalsContact O-N 3.14Å; H248-R254 WeakPolarHBondContact O-CB 3.43Å; H248-N345 PolarHBondContact CE1-OD1 3.46Å
249P96.7Very high97.7Very high21 Ų2126 Ų2614%0.13615%0.152CC..THydrogen-bonded Turntrans-56.6-33.8-178.3-25.431.5000114.9P83 S178 P180P83-P249 HydrophobicContact CB-CB 4.11Å; P83-P249 HydrophobicContact CG-CB 3.9Å; P83-P249 HydrophobicContact CG-CG 4.19Å; S178-P249 WeakPolarHBondContact O-CG 3.47Å; P180-P249 WeakPolarHBondContact O-CD 3.41Å
250D93.7Very high97.7Very high145 Ų14526.5 Ų26.578%0.77516%0.156SC*.THydrogen-bonded Turntrans-88.7-2.1-17763.4-22.8000113.7H248H248-D250 VanDerWaalsContact C-N 3.25Å; H248-D250 WeakPolarHBondContact CB-OD1 3.48Å; H248-D250 PolarHBondContact O-N 3.29Å
251S95.9Very high97.7Very high36 Ų3626.4 Ų26.425%0.25216%0.156SC..SBendtrans-75.5134.9178.8-178.50000111.2H248 L253 R254H248-S251 WeakPolarHBondContact O-CB 3.34Å; H248-S251 PolarHBondContact O-N 3.42Å; H248-S251 VanDerWaalsContact O-N 3.14Å; S251-L253 PolarHBondContact O-N 3.26Å; S251-L253 WeakPolarHBondContact OG-CB 3.46Å; S251-L253 PolarHBondContact OG-N 3.37Å; S251-R254 VanDerWaalsContact O-CB 3.27Å; S251-R254 WeakPolarHBondContact O-CB 3.32Å; S251-R254 PolarHBondContact O-N 3.25Å
252P97.3Very high97.7Very high88 Ų8825.9 Ų25.957%0.57115%0.153SC*.Hα-helixtrans-56-25.3170.4-25.234.3000113.4R254 D255 A256 L387P252-R254 VanDerWaalsContact C-N 3.29Å; P252-R254 PolarHBondContact O-N 2.99Å; P252-D255 PolarHBondContact O-N 3.27Å; P252-A256 PolarHBondContact O-N 3.44Å; P252-L387 HydrophobicContact CB-CD1 3.88Å
253L98.2Very high97.6Very high25 Ų2529.6 Ų29.613%0.13117%0.167CC..Hα-helixtrans-65.6-31.7174.3-177.661.1000112V247 S251 A256 L257 P385 L387 L392V247-L253 HydrophobicContact CG1-CB 3.93Å; V247-L253 HydrophobicContact CG1-CD2 4.14Å; V247-L253 HydrophobicContact CG1-CG 4.03Å; V247-L253 HydrophobicContact CG2-CD2 3.89Å; V247-L253 HydrophobicContact CG2-CG 4.29Å; S251-L253 PolarHBondContact O-N 3.26Å; S251-L253 WeakPolarHBondContact OG-CB 3.46Å; S251-L253 PolarHBondContact OG-N 3.37Å; L253-A256 PolarHBondContact O-N 3.38Å; L253-L257 HydrophobicContact CD1-CD1 4.48Å; L253-L257 HydrophobicContact CD1-CG 4.43Å; L253-L257 HydrophobicContact CG-CD1 4.07Å; L253-L257 HydrophobicContact CG-CG 4.48Å; L253-L257 WeakPolarHBondContact O-CB 2.99Å; L253-L257 WeakPolarHBondContact O-CG 3.33Å; L253-L257 PolarHBondContact O-N 2.83Å; L253-P385 HydrophobicContact CD1-CB 4.29Å; L253-P385 HydrophobicContact CD2-CG 4.49Å; L253-L387 HydrophobicContact CB-CG 4.35Å; L253-L387 HydrophobicContact CD1-CD2 3.9Å; L253-L387 HydrophobicContact CD1-CG 3.99Å; L253-L392 HydrophobicContact CD1-CD1 3.58Å
254R98.3Very high97.6Very high1 Ų130.7 Ų30.70%0.00417%0.171CC..Hα-helixtrans-63.9-45.4175.617055.268.3-154.7-2.4111Y87 P177 S178 S244 V247 H248 S251 P252 A256 L257 T258Y87-R254 VanDerWaalsContact OH-CD 3.24Å; Y87-R254 WeakPolarHBondContact OH-CD 3.44Å; Y87-R254 VanDerWaalsContact OH-CG 3.26Å; Y87-R254 WeakPolarHBondContact OH-CG 3.47Å; P177-R254 PolarHBondContact O-NE 3.16Å; P177-R254 PolarHBondContact O-NH1 3.41Å; S178-R254 PolarHBondContact O-NE 2.91Å; S178-R254 PolarHBondContact O-NH2 3.46Å; S244-R254 PolarHBondContact O-NH1 3.07Å; S244-R254 VanDerWaalsContact O-NH1 3.1Å; S244-R254 PolarHBondContact O-NH2 3.1Å; V247-R254 HydrophobicContact CG1-CB 4.03Å; V247-R254 PolarHBondContact O-NH2 2.67Å; H248-R254 WeakPolarHBondContact O-CB 3.43Å; S251-R254 VanDerWaalsContact O-CB 3.27Å; S251-R254 WeakPolarHBondContact O-CB 3.32Å; S251-R254 PolarHBondContact O-N 3.25Å; P252-R254 VanDerWaalsContact C-N 3.29Å; P252-R254 PolarHBondContact O-N 2.99Å; R254-A256 VanDerWaalsContact C-N 3.31Å; R254-A256 PolarHBondContact O-N 3.41Å; R254-L257 PolarHBondContact O-N 3.39Å; R254-T258 WeakPolarHBondContact O-CB 3.48Å; R254-T258 PolarHBondContact O-N 2.93Å; R254-T258 PolarHBondContact O-OG1 3.14Å
255D98.1Very high97.5Very high78 Ų7830.5 Ų30.542%0.41717%0.17SC..Hα-helixtrans-61.3-44.6177.5-72.1-4.5000110.8I90 P252 L257 T258 A259I90-D255 HydrophobicContact CD1-CB 4.33Å; I90-D255 WeakPolarHBondContact CD1-OD1 3.33Å; P252-D255 PolarHBondContact O-N 3.27Å; D255-L257 PolarHBondContact O-N 2.88Å; D255-T258 PolarHBondContact O-N 3.28Å; D255-A259 WeakPolarHBondContact O-CB 3.48Å; D255-A259 PolarHBondContact O-N 3.32Å
256A98.5Very high97.4Very high21 Ų2131.1 Ų31.117%0.17417%0.174CC..Hα-helixtrans-62.6-42.8178.400000112.3P252 L253 R254 A259 A260 L387 L392P252-A256 PolarHBondContact O-N 3.44Å; L253-A256 PolarHBondContact O-N 3.38Å; R254-A256 VanDerWaalsContact C-N 3.31Å; R254-A256 PolarHBondContact O-N 3.41Å; A256-A259 PolarHBondContact O-N 3.06Å; A256-A260 WeakPolarHBondContact O-CB 3.2Å; A256-A260 PolarHBondContact O-N 3.5Å; A256-L387 HydrophobicContact CB-CD2 3.76Å; A256-L392 HydrophobicContact CB-CB 4.12Å
257L98.7Very high97.3Very high3 Ų337.7 Ų37.72%0.01620%0.198CC..Hα-helixtrans-65.6-38.9174.7-79.1167.7000112.6L241 V247 L253 R254 D255 A260 A261 P385 L392 W394L241-L257 HydrophobicContact CB-CD2 4.4Å; L241-L257 HydrophobicContact CD1-CD2 4.23Å; V247-L257 HydrophobicContact CB-CD1 4.21Å; V247-L257 HydrophobicContact CG1-CD1 4.49Å; V247-L257 HydrophobicContact CG2-CD1 3.68Å; L253-L257 HydrophobicContact CD1-CD1 4.48Å; L253-L257 HydrophobicContact CD1-CG 4.43Å; L253-L257 HydrophobicContact CG-CD1 4.07Å; L253-L257 HydrophobicContact CG-CG 4.48Å; L253-L257 WeakPolarHBondContact O-CB 2.99Å; L253-L257 WeakPolarHBondContact O-CG 3.33Å; L253-L257 PolarHBondContact O-N 2.83Å; R254-L257 PolarHBondContact O-N 3.39Å; D255-L257 PolarHBondContact O-N 2.88Å; L257-A260 PolarHBondContact O-N 2.8Å; L257-A261 PolarHBondContact O-N 2.97Å; L257-P385 HydrophobicContact CD1-CB 4.4Å; L257-P385 HydrophobicContact CD1-CG 4.05Å; L257-P385 HydrophobicContact CD2-CB 3.86Å; L257-P385 HydrophobicContact CD2-CG 4.14Å; L257-P385 HydrophobicContact CG-CB 4.42Å; L257-L392 HydrophobicContact CD2-CD1 4.17Å; L257-L392 HydrophobicContact CD2-CD2 4.21Å; L257-L392 HydrophobicContact CG-CD1 4.29Å; L257-W394 HydrophobicContact CD2-CZ2 4.34Å
258T98.7Very high97.2Very high0 Ų037.4 Ų37.40%020%0.196CC..Hα-helixtrans-63.2-45.8177-60.20000110.6Y87 I90 I91 V176 R254 D255 A260 A261 A262Y87-T258 HydrophobicContact CD2-CG2 3.76Å; Y87-T258 HydrophobicContact CE2-CG2 4.3Å; Y87-T258 HydrophobicContact CG-CG2 4.14Å; I90-T258 HydrophobicContact CB-CG2 4.42Å; I90-T258 HydrophobicContact CG2-CG2 4.07Å; I91-T258 HydrophobicContact CD1-CG2 4.29Å; I91-T258 HydrophobicContact CG1-CG2 3.82Å; V176-T258 HydrophobicContact CG1-CG2 4.23Å; R254-T258 WeakPolarHBondContact O-CB 3.48Å; R254-T258 PolarHBondContact O-N 2.93Å; R254-T258 PolarHBondContact O-OG1 3.14Å; D255-T258 PolarHBondContact O-N 3.28Å; T258-A260 VanDerWaalsContact C-N 3.33Å; T258-A260 PolarHBondContact O-N 3.07Å; T258-A261 PolarHBondContact O-N 3.25Å; T258-A262 PolarHBondContact O-N 3.32Å
259A98.6Very high97Very high14 Ų1434.5 Ų34.512%0.11618%0.182CC..Hα-helixtrans-62.6-39.6173.300000112.1I90 A94 D255 A256 A262 R263I90-A259 HydrophobicContact CG2-CB 4.15Å; A94-A259 HydrophobicContact CB-CB 3.7Å; A94-A259 WeakPolarHBondContact CB-O 3.39Å; D255-A259 WeakPolarHBondContact O-CB 3.48Å; D255-A259 PolarHBondContact O-N 3.32Å; A256-A259 PolarHBondContact O-N 3.06Å; A259-A262 WeakPolarHBondContact O-CB 3.26Å; A259-A262 PolarHBondContact O-N 3.38Å; A259-R263 PolarHBondContact O-N 3.49Å; A259-R263 VanDerWaalsContact O-N 3.12Å
260A98.5Very high96.2Very high11 Ų1136.2 Ų36.29%0.09120%0.204CC..Hα-helixtrans-66.5-39.1177.800000112.7L241 A256 L257 T258 A262 R263 Q264 L392 W394L241-A260 HydrophobicContact CD1-CB 3.77Å; A256-A260 WeakPolarHBondContact O-CB 3.2Å; A256-A260 PolarHBondContact O-N 3.5Å; L257-A260 PolarHBondContact O-N 2.8Å; T258-A260 VanDerWaalsContact C-N 3.33Å; T258-A260 PolarHBondContact O-N 3.07Å; A260-A262 VanDerWaalsContact C-N 3.27Å; A260-A262 PolarHBondContact O-N 2.92Å; A260-R263 PolarHBondContact O-N 2.84Å; A260-Q264 VanDerWaalsContact O-CB 3.32Å; A260-Q264 WeakPolarHBondContact O-CB 3.37Å; A260-Q264 PolarHBondContact O-N 3.22Å; A260-L392 HydrophobicContact CB-CD2 3.34Å; A260-W394 HydrophobicContact CB-CH2 4.35Å
261A98.6Very high95.4Very high3 Ų333.1 Ų33.13%0.02519%0.187CC..Hα-helixtrans-61-40.4175.600000111.2L149 V174 V176 L241 L257 T258 Q264 V265L149-A261 HydrophobicContact CD2-CB 4.31Å; V174-A261 HydrophobicContact CG1-CB 3.93Å; V176-A261 HydrophobicContact CG2-CB 3.84Å; L241-A261 HydrophobicContact CD1-CB 4.07Å; L257-A261 PolarHBondContact O-N 2.97Å; T258-A261 PolarHBondContact O-N 3.25Å; A261-Q264 PolarHBondContact O-N 3.06Å; A261-Q264 VanDerWaalsContact O-N 3.16Å; A261-V265 PolarHBondContact O-N 3.41Å
262A98.5Very high94.4Very high0 Ų032.6 Ų32.60%019%0.188CC..Hα-helixtrans-63.3-40.9175.900000112.9I91 A94 L95 L149 T258 A259 A260 Q264 V265I91-A262 HydrophobicContact CB-CB 4.39Å; I91-A262 HydrophobicContact CG1-CB 4.44Å; I91-A262 HydrophobicContact CG2-CB 3.94Å; A94-A262 HydrophobicContact CB-CB 4.03Å; L95-A262 HydrophobicContact CD2-CB 4.18Å; L95-A262 VanDerWaalsContact CD2-O 3.24Å; L95-A262 WeakPolarHBondContact CD2-O 3.12Å; L95-A262 HydrophobicContact CG-CB 4.09Å; L149-A262 HydrophobicContact CD1-CB 3.98Å; T258-A262 PolarHBondContact O-N 3.32Å; A259-A262 WeakPolarHBondContact O-CB 3.26Å; A259-A262 PolarHBondContact O-N 3.38Å; A260-A262 VanDerWaalsContact C-N 3.27Å; A260-A262 PolarHBondContact O-N 2.92Å; A262-Q264 VanDerWaalsContact C-N 3.35Å; A262-V265 VanDerWaalsContact O-CG1 3.28Å; A262-V265 WeakPolarHBondContact O-CG1 3.49Å
263R97Very high93.2Very high81 Ų8135.7 Ų35.731%0.30620%0.2SC..Hα-helixtrans-71-30.7172.1-66.7-174.9-72.1-93-4.6112.6A94 E97 A98 A259 A260 T266 R267A94-R263 HydrophobicContact CB-CG 4.44Å; E97-R263 IonicContact OE2-NH1 2.89Å; E97-R263 PolarHBondContact OE2-NH1 3.26Å; A98-R263 HydrophobicContact CB-CG 4.13Å; A259-R263 PolarHBondContact O-N 3.49Å; A259-R263 VanDerWaalsContact O-N 3.12Å; A260-R263 PolarHBondContact O-N 2.84Å; R263-T266 PolarHBondContact O-OG1 3.15Å; R263-R267 WeakPolarHBondContact O-CG 3.44Å; R263-R267 PolarHBondContact O-N 2.97Å
264Q97.1Very high92.5Very high28 Ų2840.7 Ų40.713%0.13122%0.222CC..Hα-helixtrans-72-41.8-177.1-171.859.514.500111.7L241 A260 A261 A262 T266 R267 M268 V373L241-Q264 HydrophobicContact CD2-CB 4.27Å; L241-Q264 HydrophobicContact CD2-CG 4.09Å; A260-Q264 VanDerWaalsContact O-CB 3.32Å; A260-Q264 WeakPolarHBondContact O-CB 3.37Å; A260-Q264 PolarHBondContact O-N 3.22Å; A261-Q264 PolarHBondContact O-N 3.06Å; A261-Q264 VanDerWaalsContact O-N 3.16Å; A262-Q264 VanDerWaalsContact C-N 3.35Å; Q264-T266 PolarHBondContact O-N 3.31Å; Q264-R267 WeakPolarHBondContact O-CB 3.27Å; Q264-R267 PolarHBondContact O-N 3.42Å; Q264-R267 VanDerWaalsContact O-N 3.12Å; Q264-M268 PolarHBondContact O-N 2.76Å; Q264-V373 VanDerWaalsContact CD-O 3.29Å; Q264-V373 WeakPolarHBondContact CG-O 3.41Å; Q264-V373 PolarHBondContact NE2-O 3.48Å
265V97Very high92.2Very high0 Ų043.3 Ų43.30%023%0.232CC..Hα-helixtrans-61.2-34.5177.868.90000111.8I68 L149 P172 V174 A261 A262 R267 M268 T269I68-V265 HydrophobicContact CD1-CG1 4.14Å; I68-V265 HydrophobicContact CG1-CG1 4.17Å; I68-V265 HydrophobicContact CG2-CG1 3.78Å; L149-V265 HydrophobicContact CD1-CG1 4.49Å; L149-V265 HydrophobicContact CD2-CB 4.34Å; L149-V265 HydrophobicContact CD2-CG1 4.02Å; L149-V265 HydrophobicContact CG-CG1 4.11Å; P172-V265 HydrophobicContact CB-CG2 4.08Å; V174-V265 HydrophobicContact CB-CB 4.46Å; V174-V265 HydrophobicContact CG2-CB 3.81Å; V174-V265 HydrophobicContact CG2-CG2 4.26Å; A261-V265 PolarHBondContact O-N 3.41Å; A262-V265 VanDerWaalsContact O-CG1 3.28Å; A262-V265 WeakPolarHBondContact O-CG1 3.49Å; V265-R267 VanDerWaalsContact C-N 3.34Å; V265-R267 PolarHBondContact O-N 3.48Å; V265-M268 PolarHBondContact O-N 3.23Å; V265-T269 WeakPolarHBondContact O-CG2 3.42Å
266T95Very high92.1Very high13 Ų1340.7 Ų40.78%0.0822%0.218CC..Hα-helixtrans-66.9-34.2177.663.20000112.4I68 L95 A100 R263 Q264 M268 T269I68-T266 HydrophobicContact CD1-CG2 4.14Å; I68-T266 HydrophobicContact CG1-CG2 3.92Å; L95-T266 HydrophobicContact CD2-CG2 3.49Å; L95-T266 VanDerWaalsContact CD2-CG2 3.49Å; A100-T266 HydrophobicContact CB-CG2 3.59Å; R263-T266 PolarHBondContact O-OG1 3.15Å; Q264-T266 PolarHBondContact O-N 3.31Å; T266-M268 PolarHBondContact O-N 3.39Å; T266-T269 PolarHBondContact O-N 2.73Å; T266-T269 PolarHBondContact O-OG1 3.08Å
267R94.6Very high92Very high146 Ų14639.7 Ų39.755%0.55121%0.21SC*.Hα-helixtrans-67.3-25.8178.2-67.2172.572.3-167.310113.2R263 Q264 V265 N273R263-R267 WeakPolarHBondContact O-CG 3.44Å; R263-R267 PolarHBondContact O-N 2.97Å; Q264-R267 WeakPolarHBondContact O-CB 3.27Å; Q264-R267 PolarHBondContact O-N 3.42Å; Q264-R267 VanDerWaalsContact O-N 3.12Å; V265-R267 VanDerWaalsContact C-N 3.34Å; V265-R267 PolarHBondContact O-N 3.48Å; R267-N273 PolarHBondContact O-N 2.87Å
268M95.3Very high92Very high10 Ų1039.6 Ų39.65%0.04921%0.209CC..THydrogen-bonded Turntrans-88.4-6.5179.6-64.6168.758.100113.5P172 V174 Q264 V265 T266 E274 W275 M276 M281 V373P172-M268 HydrophobicContact CB-CB 3.71Å; P172-M268 HydrophobicContact CB-CE 4.31Å; P172-M268 HydrophobicContact CG-CB 4.11Å; P172-M268 WeakPolarHBondContact CG-O 3.45Å; V174-M268 HydrophobicContact CG2-SD 4.34Å; Q264-M268 PolarHBondContact O-N 2.76Å; V265-M268 PolarHBondContact O-N 3.23Å; T266-M268 PolarHBondContact O-N 3.39Å; M268-E274 CarbonylContact C-O 3.49Å; M268-E274 WeakPolarHBondContact CA-O 3.23Å; M268-W275 WeakPolarHBondContact O-CA 3.41Å; M268-M276 HydrophobicContact CB-CB 4.38Å; M268-M276 HydrophobicContact CE-CB 4.02Å; M268-M276 HydrophobicContact CE-CG 4.01Å; M268-M276 WeakPolarHBondContact CE-O 3.21Å; M268-M276 HydrophobicContact CG-CB 4.4Å; M268-M276 PolarHBondContact O-N 3.33Å; M268-M281 HydrophobicContact CE-SD 4.36Å; M268-V373 HydrophobicContact CE-CG1 4.32Å; M268-V373 HydrophobicContact SD-CB 4.22Å; M268-V373 HydrophobicContact SD-CG1 4.36Å
269T92.3Very high92Very high0 Ų039.6 Ų39.60%021%0.209CC..SBendtrans-71.8166.4177.6670000112.3N66 I68 D146 P172 V265 T266 N271 G272N66-T269 PolarHBondContact ND2-OG1 2.96Å; N66-T269 PolarHBondContact OD1-OG1 3.39Å; I68-T269 HydrophobicContact CD1-CG2 4.29Å; D146-T269 HydrophobicContact CB-CG2 4.48Å; D146-T269 WeakPolarHBondContact O-CG2 3.49Å; P172-T269 HydrophobicContact CG-CG2 4.19Å; V265-T269 WeakPolarHBondContact O-CG2 3.42Å; T266-T269 PolarHBondContact O-N 2.73Å; T266-T269 PolarHBondContact O-OG1 3.08Å; T269-N271 PolarHBondContact O-N 3.18Å; T269-N271 PolarHBondContact OG1-N 2.93Å; T269-G272 WeakPolarHBondContact O-CA 3.32Å; T269-G272 PolarHBondContact O-N 3.19Å; T269-G272 PolarHBondContact OG1-N 2.93Å
270G80.6Confident91.9Very high58 Ų5842.5 Ų42.560%0.59822%0.219SC*.THydrogen-bonded Turntrans-62-22.8173.900000114.4G272G270-G272 VanDerWaalsContact C-N 3.33Å
271N76.1Confident91.9Very high79 Ų7942 Ų4242%0.42222%0.215SC..THydrogen-bonded Turntrans-86.3-8172-64.1-35.4000112.8V35 N66 T269V35-N271 WeakPolarHBondContact CG1-ND2 3.48Å; N66-N271 WeakPolarHBondContact OD1-CB 3.24Å; N66-N271 PolarHBondContact OD1-ND2 2.86Å; T269-N271 PolarHBondContact O-N 3.18Å; T269-N271 PolarHBondContact OG1-N 2.93Å
272G75.1Confident91.9Very high26 Ų2641.9 Ų41.927%0.26821%0.214SC..SBendtrans-82.5-166.8174.600000112.2T269 G270T269-G272 WeakPolarHBondContact O-CA 3.32Å; T269-G272 PolarHBondContact O-N 3.19Å; T269-G272 PolarHBondContact OG1-N 2.93Å; G270-G272 VanDerWaalsContact C-N 3.33Å
273N72.6Confident91.9Very high153 Ų15343.5 Ų43.582%0.81822%0.223SC*.SBendtrans-78.1-32.4-177.6-67.4-11.6000112.2R267R267-N273 PolarHBondContact O-N 2.87Å
274E82.4Confident92Very high129 Ų12940.9 Ų40.960%0.60321%0.214SC*.SBendtrans-148.6110.2-172.2-169.2171.7-16800109.5M268 M276M268-E274 CarbonylContact C-O 3.49Å; M268-E274 WeakPolarHBondContact CA-O 3.23Å; E274-M276 PolarHBondContact O-N 3.28Å
275W92.2Very high92.1Very high56 Ų5642 Ų4221%0.21222%0.218CC..  trans-68.9106.1177.4177.761.6000110I27 K31 H170 M268 P277 K280I27-W275 HydrophobicContact CG2-CH2 4.43Å; K31-W275 HydrophobicContact CB-CH2 3.86Å; K31-W275 HydrophobicContact CB-CZ2 4.02Å; K31-W275 HydrophobicContact CD-CE3 4.06Å; K31-W275 HydrophobicContact CD-CH2 3.56Å; K31-W275 HydrophobicContact CD-CZ2 4.14Å; K31-W275 HydrophobicContact CD-CZ3 3.5Å; K31-W275 HydrophobicContact CG-CH2 3.67Å; K31-W275 HydrophobicContact CG-CZ2 3.76Å; K31-W275 HydrophobicContact CG-CZ3 4.07Å; H170-W275 PolarHBondContact O-NE1 3.32Å; M268-W275 WeakPolarHBondContact O-CA 3.41Å; W275-P277 HydrophobicContact CD2-CG 4.11Å; W275-P277 HydrophobicContact CE3-CG 4.33Å; W275-P277 HydrophobicContact CH2-CB 4.48Å; W275-P277 HydrophobicContact CH2-CG 3.78Å; W275-P277 HydrophobicContact CZ2-CB 3.72Å; W275-P277 HydrophobicContact CZ2-CG 3.47Å; W275-P277 VanDerWaalsContact CZ2-CG 3.47Å; W275-P277 HydrophobicContact CZ3-CG 4.2Å; W275-P277 WeakPolarHBondContact O-CD 3.34Å; W275-K280 HydrophobicContact CZ3-CD 4.27Å
276M96Very high92.2Very high24 Ų2442.1 Ų42.112%0.11822%0.219CC..  trans-121.685.9178.3-175.254.961.600109.5M268 E274 M281 N371M268-M276 HydrophobicContact CB-CB 4.38Å; M268-M276 HydrophobicContact CE-CB 4.02Å; M268-M276 HydrophobicContact CE-CG 4.01Å; M268-M276 WeakPolarHBondContact CE-O 3.21Å; M268-M276 HydrophobicContact CG-CB 4.4Å; M268-M276 PolarHBondContact O-N 3.33Å; E274-M276 PolarHBondContact O-N 3.28Å; M276-M281 HydrophobicContact CG-CB 4.31Å; M276-M281 HydrophobicContact SD-CB 4.14Å; M276-N371 HydrophobicContact CE-CB 3.87Å; M276-N371 WeakPolarHBondContact CE-OD1 3.14Å; M276-N371 HydrophobicContact SD-CB 3.79Å
277P96.8Very high92.3Very high0 Ų041.6 Ų41.60%022%0.215CC..  trans-78.1149-179.838.2-41.1000110.5I27 G169 H170 W275 G279 K280 M281I27-P277 HydrophobicContact CG2-CG 4.4Å; G169-P277 WeakPolarHBondContact O-CB 2.95Å; H170-P277 VanDerWaalsContact O-CB 3.25Å; H170-P277 WeakPolarHBondContact O-CB 3.47Å; W275-P277 HydrophobicContact CD2-CG 4.11Å; W275-P277 HydrophobicContact CE3-CG 4.33Å; W275-P277 HydrophobicContact CH2-CB 4.48Å; W275-P277 HydrophobicContact CH2-CG 3.78Å; W275-P277 HydrophobicContact CZ2-CB 3.72Å; W275-P277 HydrophobicContact CZ2-CG 3.47Å; W275-P277 VanDerWaalsContact CZ2-CG 3.47Å; W275-P277 HydrophobicContact CZ3-CG 4.2Å; W275-P277 WeakPolarHBondContact O-CD 3.34Å; P277-G279 PolarHBondContact O-N 3.01Å; P277-G279 VanDerWaalsContact O-N 3.16Å; P277-K280 HydrophobicContact CG-CB 3.89Å; P277-K280 HydrophobicContact CG-CD 3.87Å; P277-K280 HydrophobicContact CG-CG 3.74Å; P277-K280 PolarHBondContact O-N 3.17Å; P277-M281 PolarHBondContact O-N 3.1Å
278I98.4Very high92.5Very high1 Ų134.6 Ų34.61%0.00519%0.189CC..Hα-helixtrans-60.1-33.4-174-172.1167.7000112.8A165 L166 L171 A173 F175 M239 K280 M281 I282A165-I278 HydrophobicContact CB-CD1 3.91Å; A165-I278 HydrophobicContact CB-CG2 4.48Å; A165-I278 WeakPolarHBondContact O-CG2 3.45Å; L166-I278 HydrophobicContact CD2-CG1 4.26Å; L171-I278 WeakPolarHBondContact O-CG2 3.41Å; L171-I278 PolarHBondContact O-N 3.05Å; A173-I278 HydrophobicContact CB-CB 3.85Å; A173-I278 HydrophobicContact CB-CD1 3.69Å; A173-I278 HydrophobicContact CB-CG1 4.3Å; A173-I278 HydrophobicContact CB-CG2 4.02Å; F175-I278 HydrophobicContact CE2-CD1 4.32Å; M239-I278 HydrophobicContact CE-CD1 4.01Å; I278-K280 PolarHBondContact O-N 2.87Å; I278-M281 HydrophobicContact CG1-CE 4.19Å; I278-M281 PolarHBondContact O-N 3.37Å; I278-I282 HydrophobicContact CD1-CG1 4.44Å; I278-I282 HydrophobicContact CG1-CG1 3.8Å; I278-I282 WeakPolarHBondContact O-CG1 3.03Å; I278-I282 PolarHBondContact O-N 3.23Å
279G98.3Very high92.7Very high0 Ų034.1 Ų34.10%019%0.187CC..Hα-helixtrans-65.1-26.1178.100000113.8R20 Y23 G169 P277R20-G279 PolarHBondContact NH1-O 2.92Å; R20-G279 PolarHBondContact NH2-O 3.46Å; Y23-G279 WeakPolarHBondContact OH-CA 3.43Å; G169-G279 VanDerWaalsContact O-CA 3.29Å; G169-G279 WeakPolarHBondContact O-CA 3.24Å; G169-G279 PolarHBondContact O-N 3.16Å; P277-G279 PolarHBondContact O-N 3.01Å; P277-G279 VanDerWaalsContact O-N 3.16Å
280K97.6Very high93Very high74 Ų7434.1 Ų34.132%0.32219%0.187SC..Hα-helixtrans-88.3-35.2171.3-67.7-171.1-177.8-170.70112.3L24 E28 W275 P277 I278L24-K280 HydrophobicContact CD2-CG 4.17Å; E28-K280 IonicContact OE2-NZ 2.87Å; E28-K280 PolarHBondContact OE2-NZ 3.44Å; W275-K280 HydrophobicContact CZ3-CD 4.27Å; P277-K280 HydrophobicContact CG-CB 3.89Å; P277-K280 HydrophobicContact CG-CD 3.87Å; P277-K280 HydrophobicContact CG-CG 3.74Å; P277-K280 PolarHBondContact O-N 3.17Å; I278-K280 PolarHBondContact O-N 2.87Å
281M98.2Very high93.8Very high1 Ų131.4 Ų31.41%0.00516%0.158CC..Hα-helixtrans-62.7-45.1177.1-171.4-177.179.700111.4M239 M268 M276 P277 I278 D283 V286 N371 V373M239-M281 HydrophobicContact CB-CE 4.34Å; M239-M281 HydrophobicContact CG-CE 3.72Å; M268-M281 HydrophobicContact CE-SD 4.36Å; M276-M281 HydrophobicContact CG-CB 4.31Å; M276-M281 HydrophobicContact SD-CB 4.14Å; P277-M281 PolarHBondContact O-N 3.1Å; I278-M281 HydrophobicContact CG1-CE 4.19Å; I278-M281 PolarHBondContact O-N 3.37Å; M281-D283 PolarHBondContact O-N 2.88Å; M281-V286 WeakPolarHBondContact O-CG2 3.42Å; M281-N371 HydrophobicContact CG-CB 4.21Å; M281-N371 WeakPolarHBondContact CG-O 3.31Å; M281-V373 HydrophobicContact CE-CG1 4.05Å; M281-V373 HydrophobicContact SD-CG1 3.83Å
282I98.6Very high94.9Very high1 Ų127.6 Ų27.61%0.00514%0.138CC..SBendtrans-82.2104.3175.8-54.9-52.1000109.1R20 L166 M237 M239 I278 V286 V287 A314R20-I282 PolarHBondContact NH1-O 2.75Å; R20-I282 VanDerWaalsContact NH1-O 3.16Å; R20-I282 PolarHBondContact NH2-O 3.46Å; L166-I282 HydrophobicContact CD2-CB 3.97Å; L166-I282 HydrophobicContact CD2-CG1 3.99Å; L166-I282 HydrophobicContact CD2-CG2 4.35Å; M237-I282 HydrophobicContact CE-CD1 4.18Å; M237-I282 HydrophobicContact CE-CG2 4.34Å; M239-I282 HydrophobicContact CG-CD1 3.65Å; M239-I282 HydrophobicContact SD-CD1 3.75Å; I278-I282 HydrophobicContact CD1-CG1 4.44Å; I278-I282 HydrophobicContact CG1-CG1 3.8Å; I278-I282 WeakPolarHBondContact O-CG1 3.03Å; I278-I282 PolarHBondContact O-N 3.23Å; I282-V286 HydrophobicContact CD1-CG1 3.66Å; I282-V287 HydrophobicContact CG2-CG2 4.14Å; I282-A314 HydrophobicContact CG2-CB 4.29Å
283D98.7Very high96Very high34 Ų3426.4 Ų26.418%0.18213%0.126CC..  trans-118.9-177.117271.512.6000111.5M281 K285 V286 V287 I316M281-D283 PolarHBondContact O-N 2.88Å; D283-K285 PolarHBondContact O-N 3.05Å; D283-K285 WeakPolarHBondContact OD1-CA 3.25Å; D283-K285 WeakPolarHBondContact OD1-CB 3.46Å; D283-K285 PolarHBondContact OD1-N 3.04Å; D283-V286 PolarHBondContact O-N 2.89Å; D283-V286 WeakPolarHBondContact OD1-CG2 3.48Å; D283-V286 PolarHBondContact OD1-N 3.46Å; D283-V287 WeakPolarHBondContact O-CG2 3.25Å; D283-V287 PolarHBondContact O-N 3.18Å; D283-I316 VanDerWaalsContact C-CD1 3.41Å
284E98.8Very high97.1Very high25 Ų2519.1 Ų19.112%0.1179%0.087CC..Hα-helixtrans-59.7-35.1-179.2-63.490.7150.900112.5I12 I13 V287 V288 I316I12-E284 HydrophobicContact CG2-CB 4.13Å; I12-E284 HydrophobicContact CG2-CG 3.95Å; I13-E284 HydrophobicContact CG1-CB 3.7Å; I13-E284 HydrophobicContact CG1-CG 3.72Å; E284-V287 PolarHBondContact O-N 3.39Å; E284-V288 VanDerWaalsContact O-CG2 3.31Å; E284-V288 WeakPolarHBondContact O-CG2 3.48Å; E284-V288 PolarHBondContact O-N 3.19Å; E284-I316 HydrophobicContact CG-CD1 4.43Å; E284-I316 HydrophobicContact CG-CG1 4.21Å; E284-I316 HydrophobicContact CG-CG2 4.04Å
285K98.9Very high97.7Very high53 Ų5313 Ų1323%0.236%0.058CC..Hα-helixtrans-69.6-43.1178.4-65.2179.1-177.71750111T9 D283 V287 V288 N289 H367 D369 V370T9-K285 HydrophobicContact CG2-CG 4.13Å; D283-K285 PolarHBondContact O-N 3.05Å; D283-K285 WeakPolarHBondContact OD1-CA 3.25Å; D283-K285 WeakPolarHBondContact OD1-CB 3.46Å; D283-K285 PolarHBondContact OD1-N 3.04Å; K285-V287 VanDerWaalsContact C-N 3.34Å; K285-V287 PolarHBondContact O-N 2.72Å; K285-V288 PolarHBondContact O-N 3.16Å; K285-N289 PolarHBondContact O-N 3.09Å; K285-H367 HydrophobicContact CB-CB 3.82Å; K285-H367 HydrophobicContact CD-CB 4.15Å; K285-H367 HydrophobicContact CG-CB 4.26Å; K285-D369 VanDerWaalsContact NZ-CG 3.31Å; K285-D369 IonicContact NZ-OD1 3.83Å; K285-D369 IonicContact NZ-OD2 2.85Å; K285-D369 PolarHBondContact NZ-OD2 3.22Å; K285-V370 HydrophobicContact CB-CG1 3.73Å; K285-V370 HydrophobicContact CD-CG1 4.33Å
286V98.8Very high98Very high1 Ų110.3 Ų10.31%0.0065%0.048CC..Hα-helixtrans-62.1-42.1175.71720000111.1M237 M281 I282 D283 V288 N289 G290 V370M237-V286 HydrophobicContact CB-CG1 3.75Å; M237-V286 HydrophobicContact CE-CG1 4.22Å; M237-V286 HydrophobicContact CG-CG1 4.04Å; M237-V286 VanDerWaalsContact O-CG1 3.25Å; M237-V286 WeakPolarHBondContact O-CG1 3.44Å; M281-V286 WeakPolarHBondContact O-CG2 3.42Å; I282-V286 HydrophobicContact CD1-CG1 3.66Å; D283-V286 PolarHBondContact O-N 2.89Å; D283-V286 WeakPolarHBondContact OD1-CG2 3.48Å; D283-V286 PolarHBondContact OD1-N 3.46Å; V286-V288 PolarHBondContact O-N 2.89Å; V286-N289 WeakPolarHBondContact O-CB 3.02Å; V286-N289 PolarHBondContact O-N 3.39Å; V286-G290 PolarHBondContact O-N 3.29Å; V286-V370 HydrophobicContact CG2-CB 3.8Å; V286-V370 HydrophobicContact CG2-CG1 3.83Å; V286-V370 HydrophobicContact CG2-CG2 4.45Å
287V98.8Very high97.9Very high2 Ų29.2 Ų9.21%0.0124%0.042CC..Hα-helixtrans-61.7-43.8174.2172.40000111.2I282 D283 E284 K285 N289 G290 I291 A311 I316 I318I282-V287 HydrophobicContact CG2-CG2 4.14Å; D283-V287 WeakPolarHBondContact O-CG2 3.25Å; D283-V287 PolarHBondContact O-N 3.18Å; E284-V287 PolarHBondContact O-N 3.39Å; K285-V287 VanDerWaalsContact C-N 3.34Å; K285-V287 PolarHBondContact O-N 2.72Å; V287-N289 PolarHBondContact O-N 3.35Å; V287-G290 PolarHBondContact O-N 3.26Å; V287-G290 VanDerWaalsContact O-N 3.16Å; V287-I291 HydrophobicContact CG1-CD1 4.47Å; V287-I291 PolarHBondContact O-N 2.9Å; V287-A311 HydrophobicContact CG1-CB 3.96Å; V287-A311 HydrophobicContact CG2-CB 4.1Å; V287-I316 HydrophobicContact CG2-CD1 3.76Å; V287-I316 HydrophobicContact CG2-CG2 4.37Å; V287-I318 HydrophobicContact CG1-CD1 3.9Å; V287-I318 HydrophobicContact CG1-CG2 3.87Å
288V98.8Very high97.7Very high0 Ų09.2 Ų9.20%04%0.042CC..Hα-helixtrans-61.7-41.9175.4168.50000111.5L5 T9 I12 E284 K285 V286 G290 I291 V292 L326L5-V288 HydrophobicContact CD1-CG1 4.36Å; L5-V288 HydrophobicContact CD2-CG1 4.32Å; L5-V288 HydrophobicContact CG-CG1 4.06Å; T9-V288 HydrophobicContact CG2-CG2 4.45Å; I12-V288 HydrophobicContact CD1-CG2 3.6Å; E284-V288 VanDerWaalsContact O-CG2 3.31Å; E284-V288 WeakPolarHBondContact O-CG2 3.48Å; E284-V288 PolarHBondContact O-N 3.19Å; K285-V288 PolarHBondContact O-N 3.16Å; V286-V288 PolarHBondContact O-N 2.89Å; V288-G290 VanDerWaalsContact C-N 3.27Å; V288-G290 PolarHBondContact O-N 3.35Å; V288-I291 PolarHBondContact O-N 3.5Å; V288-I291 VanDerWaalsContact O-N 3.09Å; V288-V292 HydrophobicContact CG1-CG2 4.34Å; V288-V292 WeakPolarHBondContact O-CG2 3.46Å; V288-V292 PolarHBondContact O-N 2.81Å; V288-L326 HydrophobicContact CG1-CD1 4.23Å; V288-L326 HydrophobicContact CG1-CD2 4.35Å
289N98.8Very high97.4Very high0 Ų09.1 Ų9.10%04%0.042CC..Hα-helixtrans-59.1-39174.3-72.8-8.5000111.8K285 V286 V287 V292 A293 L366 H367K285-N289 PolarHBondContact O-N 3.09Å; V286-N289 WeakPolarHBondContact O-CB 3.02Å; V286-N289 PolarHBondContact O-N 3.39Å; V287-N289 PolarHBondContact O-N 3.35Å; N289-V292 PolarHBondContact O-N 3.14Å; N289-A293 WeakPolarHBondContact O-CB 3.48Å; N289-A293 PolarHBondContact O-N 3.4Å; N289-L366 HydrophobicContact CB-CD2 3.85Å; N289-L366 WeakPolarHBondContact OD1-CA 3.48Å; N289-H367 PolarHBondContact ND2-O 3.01Å; N289-H367 PolarHBondContact OD1-N 3.03Å
290G98.5Very high97.1Very high0 Ų09.1 Ų9.10%04%0.042CC..Hα-helixtrans-62-40.517300000113.4V286 V287 V288 A293 L294V286-G290 PolarHBondContact O-N 3.29Å; V287-G290 PolarHBondContact O-N 3.26Å; V287-G290 VanDerWaalsContact O-N 3.16Å; V288-G290 VanDerWaalsContact C-N 3.27Å; V288-G290 PolarHBondContact O-N 3.35Å; G290-A293 WeakPolarHBondContact O-CB 3.33Å; G290-A293 PolarHBondContact O-N 3.37Å; G290-L294 PolarHBondContact O-N 3.04Å; G290-L294 VanDerWaalsContact O-N 3.11Å
291I98.3Very high96.9Very high0 Ų05.9 Ų5.90%03%0.028CC..Hα-helixtrans-66.4-42.4174.5-60.7168.8000110.7V287 V288 A293 L294 L295 L307 I318 F323 L326V287-I291 HydrophobicContact CG1-CD1 4.47Å; V287-I291 PolarHBondContact O-N 2.9Å; V288-I291 PolarHBondContact O-N 3.5Å; V288-I291 VanDerWaalsContact O-N 3.09Å; I291-A293 VanDerWaalsContact C-N 3.32Å; I291-A293 PolarHBondContact O-N 2.85Å; I291-L294 WeakPolarHBondContact O-CB 3.41Å; I291-L294 PolarHBondContact O-N 3.46Å; I291-L295 HydrophobicContact CG2-CD1 3.78Å; I291-L295 HydrophobicContact CG2-CG 4.29Å; I291-L295 VanDerWaalsContact O-CG 3.29Å; I291-L295 WeakPolarHBondContact O-CG 3.41Å; I291-L295 PolarHBondContact O-N 3.37Å; I291-L307 HydrophobicContact CG1-CD1 4.1Å; I291-I318 HydrophobicContact CD1-CD1 3.94Å; I291-I318 HydrophobicContact CD1-CG2 4.45Å; I291-F323 HydrophobicContact CB-CE1 4.44Å; I291-F323 HydrophobicContact CD1-CE1 4.42Å; I291-F323 HydrophobicContact CD1-CE2 4.32Å; I291-F323 HydrophobicContact CD1-CZ 4.19Å; I291-F323 HydrophobicContact CG1-CD1 4.4Å; I291-F323 HydrophobicContact CG1-CE1 3.88Å; I291-F323 HydrophobicContact CG1-CZ 3.99Å; I291-F323 HydrophobicContact CG2-CD1 3.67Å; I291-F323 HydrophobicContact CG2-CE1 3.95Å; I291-F323 HydrophobicContact CG2-CG 4.23Å; I291-L326 HydrophobicContact CB-CD1 3.99Å; I291-L326 HydrophobicContact CD1-CD1 4.19Å; I291-L326 HydrophobicContact CG2-CB 4.44Å; I291-L326 HydrophobicContact CG2-CD1 3.59Å
292V98.4Very high96.8Very high0 Ų05.8 Ų5.80%03%0.028CC..Hα-helixtrans-60.2-43.4175.8172.40000110.5L5 V288 N289 L294 L295 A296 V330 L360 L365 L366L5-V292 HydrophobicContact CD1-CG2 4.03Å; V288-V292 HydrophobicContact CG1-CG2 4.34Å; V288-V292 WeakPolarHBondContact O-CG2 3.46Å; V288-V292 PolarHBondContact O-N 2.81Å; N289-V292 PolarHBondContact O-N 3.14Å; V292-L294 VanDerWaalsContact C-N 3.34Å; V292-L294 PolarHBondContact O-N 3.09Å; V292-L295 PolarHBondContact O-N 3.27Å; V292-A296 VanDerWaalsContact O-CB 3.24Å; V292-A296 WeakPolarHBondContact O-CB 3.49Å; V292-A296 PolarHBondContact O-N 3.4Å; V292-V330 HydrophobicContact CB-CG2 4.35Å; V292-V330 HydrophobicContact CG1-CG1 3.98Å; V292-V330 HydrophobicContact CG1-CG2 4.08Å; V292-V330 HydrophobicContact CG2-CG2 3.91Å; V292-L360 HydrophobicContact CG1-CD1 4.11Å; V292-L360 HydrophobicContact CG1-CD2 4.25Å; V292-L365 WeakPolarHBondContact CG1-O 3.46Å; V292-L365 VanDerWaalsContact CG2-O 3.31Å; V292-L365 WeakPolarHBondContact CG2-O 3.41Å; V292-L366 HydrophobicContact CB-CD2 3.94Å; V292-L366 HydrophobicContact CG1-CD2 3.73Å; V292-L366 HydrophobicContact CG1-CG 4.3Å
293A97.6Very high96.6Very high0 Ų05.8 Ų5.80%03%0.028CC..Hα-helixtrans-58.1-46.5176.700000111.8V233 F236 N289 G290 I291 L295 T297V233-A293 HydrophobicContact CG2-CB 4.32Å; F236-A293 HydrophobicContact CB-CB 3.55Å; F236-A293 HydrophobicContact CD1-CB 3.4Å; F236-A293 HydrophobicContact CD2-CB 4.05Å; F236-A293 HydrophobicContact CE1-CB 4.03Å; F236-A293 HydrophobicContact CG-CB 3.4Å; N289-A293 WeakPolarHBondContact O-CB 3.48Å; N289-A293 PolarHBondContact O-N 3.4Å; G290-A293 WeakPolarHBondContact O-CB 3.33Å; G290-A293 PolarHBondContact O-N 3.37Å; I291-A293 VanDerWaalsContact C-N 3.32Å; I291-A293 PolarHBondContact O-N 2.85Å; A293-L295 PolarHBondContact O-N 2.91Å; A293-T297 WeakPolarHBondContact O-CB 3.25Å; A293-T297 WeakPolarHBondContact O-CG2 3.47Å; A293-T297 PolarHBondContact O-N 3.23Å; A293-T297 PolarHBondContact O-OG1 3.32Å
294L96.1Very high96.5Very high1 Ų14.2 Ų4.21%0.0052%0.019CC..Hα-helixtrans-56.8-48.5176.6171.666.7000111.5T229 V233 G290 I291 V292 T297 G298 G299 S300 H303 L307 F323T229-L294 HydrophobicContact CG2-CD1 3.64Å; V233-L294 HydrophobicContact CG2-CB 4.33Å; G290-L294 PolarHBondContact O-N 3.04Å; G290-L294 VanDerWaalsContact O-N 3.11Å; I291-L294 WeakPolarHBondContact O-CB 3.41Å; I291-L294 PolarHBondContact O-N 3.46Å; V292-L294 VanDerWaalsContact C-N 3.34Å; V292-L294 PolarHBondContact O-N 3.09Å; L294-T297 PolarHBondContact O-OG1 3.02Å; L294-G298 PolarHBondContact O-N 2.9Å; L294-G298 VanDerWaalsContact O-N 3.13Å; L294-G299 PolarHBondContact O-N 3.35Å; L294-S300 WeakPolarHBondContact CD1-O 3.3Å; L294-H303 HydrophobicContact CD1-CB 3.76Å; L294-H303 HydrophobicContact CD2-CB 3.68Å; L294-H303 HydrophobicContact CG-CB 4.3Å; L294-L307 HydrophobicContact CD2-CD1 4.13Å; L294-F323 HydrophobicContact CD2-CD1 4.06Å; L294-F323 HydrophobicContact CD2-CE1 3.74Å
295L96Very high96.4Very high0 Ų03 Ų30%01%0.014CC..Hα-helixtrans-70.8-47.1-176.6-68.3170.5000111.9I291 V292 A293 T297 G298 L326 V330 G418I291-L295 HydrophobicContact CG2-CD1 3.78Å; I291-L295 HydrophobicContact CG2-CG 4.29Å; I291-L295 VanDerWaalsContact O-CG 3.29Å; I291-L295 WeakPolarHBondContact O-CG 3.41Å; I291-L295 PolarHBondContact O-N 3.37Å; V292-L295 PolarHBondContact O-N 3.27Å; A293-L295 PolarHBondContact O-N 2.91Å; L295-T297 PolarHBondContact O-N 2.88Å; L295-T297 VanDerWaalsContact O-N 3.1Å; L295-G298 PolarHBondContact O-N 2.88Å; L295-G298 VanDerWaalsContact O-N 3.1Å; L295-L326 HydrophobicContact CD1-CB 3.64Å; L295-V330 HydrophobicContact CB-CB 4.06Å; L295-V330 HydrophobicContact CB-CG1 3.74Å; L295-V330 HydrophobicContact CD1-CB 4.28Å; L295-V330 HydrophobicContact CD1-CG2 4.36Å; L295-G418 CarbonylContact O-C 3.51Å
296A96.6Very high96.4Very high0 Ų00.5 Ų0.50%00%0.003CC..Hα-helixtrans-63-22.6-177.800000113.1V292 V330 P331 M333 A334 L360V292-A296 VanDerWaalsContact O-CB 3.24Å; V292-A296 WeakPolarHBondContact O-CB 3.49Å; V292-A296 PolarHBondContact O-N 3.4Å; A296-V330 HydrophobicContact CB-CG1 3.83Å; A296-P331 VanDerWaalsContact CA-O 3.31Å; A296-P331 WeakPolarHBondContact CA-O 3.49Å; A296-M333 PolarHBondContact O-N 3.25Å; A296-A334 PolarHBondContact O-N 3.48Å; A296-A334 VanDerWaalsContact O-N 3.16Å; A296-L360 HydrophobicContact CB-CD1 3.83Å; A296-L360 HydrophobicContact CB-CD2 4.16Å
297T94.8Very high96.3Very high0 Ų00.5 Ų0.50%00%0.003CC..THydrogen-bonded Turntrans-105.7-4.8179.158.50000114.2Y224 M232 A293 L294 L295 G299 A334 N339 L356Y224-T297 VanDerWaalsContact CE1-CB 3.5Å; Y224-T297 VanDerWaalsContact CE1-O 3.3Å; Y224-T297 WeakPolarHBondContact CE1-O 3.48Å; Y224-T297 WeakPolarHBondContact CE1-OG1 3.26Å; Y224-T297 WeakPolarHBondContact OH-CB 3.49Å; Y224-T297 PolarHBondContact OH-OG1 2.95Å; M232-T297 HydrophobicContact CE-CG2 3.79Å; A293-T297 WeakPolarHBondContact O-CB 3.25Å; A293-T297 WeakPolarHBondContact O-CG2 3.47Å; A293-T297 PolarHBondContact O-N 3.23Å; A293-T297 PolarHBondContact O-OG1 3.32Å; L294-T297 PolarHBondContact O-OG1 3.02Å; L295-T297 PolarHBondContact O-N 2.88Å; L295-T297 VanDerWaalsContact O-N 3.1Å; T297-G299 VanDerWaalsContact C-N 3.33Å; T297-G299 PolarHBondContact O-N 2.76Å; T297-A334 HydrophobicContact CG2-CB 4.13Å; T297-N339 PolarHBondContact O-ND2 3.22Å; T297-L356 HydrophobicContact CG2-CD1 3.63Å
298G92Very high96.3Very high0 Ų00.5 Ų0.50%00%0.003CC..THydrogen-bonded Turntrans57.846.3-173.400000111.9L294 L295 L332 N339 K433L294-G298 PolarHBondContact O-N 2.9Å; L294-G298 VanDerWaalsContact O-N 3.13Å; L295-G298 PolarHBondContact O-N 2.88Å; L295-G298 VanDerWaalsContact O-N 3.1Å; G298-L332 VanDerWaalsContact N-CD1 3.34Å; G298-N339 PolarHBondContact O-ND2 2.98Å; G298-K433 WeakPolarHBondContact O-CE 3.48Å; G298-K433 PolarHBondContact O-NZ 3.49Å
299G92.7Very high96.3Very high0 Ų00.5 Ų0.50%00%0.003CC..  trans-71.2-175.9-176.300000114.4L294 T297 T301L294-G299 PolarHBondContact O-N 3.35Å; T297-G299 VanDerWaalsContact C-N 3.33Å; T297-G299 PolarHBondContact O-N 2.76Å; G299-T301 PolarHBondContact O-N 3.12Å
300S93Very high96.3Very high0 Ų00.7 Ų0.70%00%0.004CC..  trans-64.5130.6-175.3-178.60000112.5T226 T229 L294 N302 H303 G514T226-S300 WeakPolarHBondContact OG1-CB 3.2Å; T226-S300 PolarHBondContact OG1-OG 3.08Å; T229-S300 PolarHBondContact OG1-N 3.3Å; T229-S300 VanDerWaalsContact OG1-N 3.09Å; L294-S300 WeakPolarHBondContact CD1-O 3.3Å; S300-N302 PolarHBondContact O-N 2.93Å; S300-N302 VanDerWaalsContact O-N 3.11Å; S300-N302 PolarHBondContact OG-N 2.97Å; S300-H303 WeakPolarHBondContact O-CB 3.46Å; S300-H303 PolarHBondContact O-N 2.7Å; S300-G514 VanDerWaalsContact OG-CA 3.27Å; S300-G514 WeakPolarHBondContact OG-CA 3.49Å
301T93.4Very high96.3Very high5 Ų50.8 Ų0.83%0.0311%0.005CC..THydrogen-bonded Turntrans-58.7-20.9173.545.20000113.2G299 H303 T304 V431 K433 I523G299-T301 PolarHBondContact O-N 3.12Å; T301-H303 PolarHBondContact O-N 2.59Å; T301-H303 VanDerWaalsContact O-N 3.11Å; T301-T304 WeakPolarHBondContact O-CB 3.34Å; T301-T304 WeakPolarHBondContact O-CG2 3.3Å; T301-T304 PolarHBondContact O-N 3.29Å; T301-T304 PolarHBondContact O-OG1 3.5Å; T301-V431 HydrophobicContact CG2-CG2 4.42Å; T301-K433 HydrophobicContact CG2-CB 3.91Å; T301-I523 HydrophobicContact CG2-CD1 4.26Å; T301-I523 VanDerWaalsContact OG1-CD1 3.24Å; T301-I523 WeakPolarHBondContact OG1-CD1 3.49Å
302N94.8Very high96.3Very high0 Ų05 Ų50%02%0.02CC..THydrogen-bonded Turntrans-54.8-28.7171.3-76.8-20.7000112.7D155 T226 S300 T304 M305 H306 E486 R511D155-N302 PolarHBondContact OD2-ND2 2.9Å; T226-N302 HydrophobicContact CG2-CB 3.85Å; T226-N302 PolarHBondContact OG1-ND2 3.17Å; S300-N302 PolarHBondContact O-N 2.93Å; S300-N302 VanDerWaalsContact O-N 3.11Å; S300-N302 PolarHBondContact OG-N 2.97Å; N302-T304 PolarHBondContact O-N 3.11Å; N302-M305 HydrophobicContact CB-CE 4.46Å; N302-M305 PolarHBondContact O-N 3.02Å; N302-H306 PolarHBondContact O-N 2.81Å; N302-E486 PolarHBondContact ND2-OE1 3.32Å; N302-R511 WeakPolarHBondContact OD1-CD 3.48Å
303H95.7Very high96.3Very high0 Ų05 Ų50%02%0.021CC..Hα-helixtrans-67.7-19.1177.5-78.464.6000113.6T226 T229 N230 L294 S300 T301 M305 H306 L307T226-H303 VanDerWaalsContact CG2-CE1 3.46Å; T226-H303 WeakPolarHBondContact CG2-CE1 3.22Å; T229-H303 VanDerWaalsContact CB-CE1 3.48Å; T229-H303 WeakPolarHBondContact CB-CE1 3.08Å; T229-H303 VanDerWaalsContact CG2-CE1 3.41Å; T229-H303 WeakPolarHBondContact CG2-CE1 3.45Å; N230-H303 WeakPolarHBondContact CA-NE2 3.46Å; N230-H303 PolarHBondContact N-NE2 3.25Å; N230-H303 PolarHBondContact OD1-CE1 3.19Å; N230-H303 PolarHBondContact OD1-NE2 3.13Å; L294-H303 HydrophobicContact CD1-CB 3.76Å; L294-H303 HydrophobicContact CD2-CB 3.68Å; L294-H303 HydrophobicContact CG-CB 4.3Å; S300-H303 WeakPolarHBondContact O-CB 3.46Å; S300-H303 PolarHBondContact O-N 2.7Å; T301-H303 PolarHBondContact O-N 2.59Å; T301-H303 VanDerWaalsContact O-N 3.11Å; H303-M305 PolarHBondContact O-N 2.94Å; H303-H306 PolarHBondContact O-N 3.19Å; H303-L307 HydrophobicContact CB-CD1 4.14Å; H303-L307 HydrophobicContact CB-CG 4.49Å; H303-L307 VanDerWaalsContact O-CB 3.25Å; H303-L307 WeakPolarHBondContact O-CB 3.12Å; H303-L307 PolarHBondContact O-N 3.23Å
304T95.7Very high96.4Very high1 Ų15 Ų51%0.0062%0.021CC..Hα-helixtrans-65.2-1717166.30000112.6T301 N302 V308 W320 F323 T420 V431T301-T304 WeakPolarHBondContact O-CB 3.34Å; T301-T304 WeakPolarHBondContact O-CG2 3.3Å; T301-T304 PolarHBondContact O-N 3.29Å; T301-T304 PolarHBondContact O-OG1 3.5Å; N302-T304 PolarHBondContact O-N 3.11Å; T304-V308 WeakPolarHBondContact O-CG2 3.24Å; T304-W320 PolarHBondContact O-NE1 2.95Å; T304-F323 HydrophobicContact CG2-CD1 4.22Å; T304-F323 HydrophobicContact CG2-CE1 4.35Å; T304-T420 HydrophobicContact CG2-CG2 4.39Å; T304-V431 HydrophobicContact CG2-CG1 4.29Å
305M97.4Very high96.5Very high0 Ų05.4 Ų5.40%03%0.025CC..Hα-helixtrans-102.3-44.9171.2-59.6175.5-67.900111.2N302 H303 L307 V308 A309 M484 H524 A594 G597 A598N302-M305 HydrophobicContact CB-CE 4.46Å; N302-M305 PolarHBondContact O-N 3.02Å; H303-M305 PolarHBondContact O-N 2.94Å; M305-L307 PolarHBondContact O-N 2.97Å; M305-V308 PolarHBondContact O-N 3.1Å; M305-A309 PolarHBondContact O-N 3.07Å; M305-M484 HydrophobicContact CE-CE 3.25Å; M305-M484 HydrophobicContact SD-CE 3.18Å; M305-M484 WeakPolarHBondContact SD-CE 3.31Å; M305-M484 HydrophobicContact SD-SD 3.84Å; M305-H524 WeakPolarHBondContact CE-CE1 3.4Å; M305-H524 WeakPolarHBondContact CE-NE2 3.39Å; M305-A594 HydrophobicContact CG-CB 4.22Å; M305-A594 WeakPolarHBondContact CG-O 3.27Å; M305-A594 HydrophobicContact SD-CB 3.82Å; M305-G597 WeakPolarHBondContact O-CA 3.35Å; M305-A598 HydrophobicContact SD-CB 4.24Å
306H97.7Very high96.6Very high0 Ų05.4 Ų5.40%03%0.025CC..Hα-helixtrans-63.1-44.6-176.4-60.9-31.7000112.1D155 P159 N302 H303 V308 A309 M310D155-H306 IonicContact OD1-CD2 3.84Å; D155-H306 IonicContact OD1-CE1 2.73Å; D155-H306 IonicContact OD1-NE2 2.73Å; D155-H306 PolarHBondContact OD1-NE2 3.09Å; P159-H306 HydrophobicContact CB-CB 3.93Å; P159-H306 HydrophobicContact CG-CB 3.66Å; N302-H306 PolarHBondContact O-N 2.81Å; H303-H306 PolarHBondContact O-N 3.19Å; H306-V308 VanDerWaalsContact C-N 3.29Å; H306-V308 PolarHBondContact O-N 3.42Å; H306-A309 PolarHBondContact O-N 3.04Å; H306-M310 HydrophobicContact CB-CE 4.21Å; H306-M310 WeakPolarHBondContact O-CB 3.26Å; H306-M310 VanDerWaalsContact O-CG 3.25Å; H306-M310 WeakPolarHBondContact O-CG 3.35Å; H306-M310 PolarHBondContact O-N 2.68Å
307L98.2Very high96.7Very high2 Ų28.2 Ų8.21%0.014%0.038CC..Hα-helixtrans-64.1-36.3177-77.2163000111.6V233 M237 I291 L294 H303 M305 M310 A311 I318 F323V233-L307 HydrophobicContact CG1-CD2 3.93Å; M237-L307 HydrophobicContact SD-CD2 4.11Å; I291-L307 HydrophobicContact CG1-CD1 4.1Å; L294-L307 HydrophobicContact CD2-CD1 4.13Å; H303-L307 HydrophobicContact CB-CD1 4.14Å; H303-L307 HydrophobicContact CB-CG 4.49Å; H303-L307 VanDerWaalsContact O-CB 3.25Å; H303-L307 WeakPolarHBondContact O-CB 3.12Å; H303-L307 PolarHBondContact O-N 3.23Å; M305-L307 PolarHBondContact O-N 2.97Å; L307-M310 HydrophobicContact CB-CE 4.46Å; L307-M310 HydrophobicContact CD2-CE 3.75Å; L307-M310 HydrophobicContact CG-CE 4Å; L307-M310 PolarHBondContact O-N 3.03Å; L307-A311 WeakPolarHBondContact O-CB 3.4Å; L307-A311 PolarHBondContact O-N 2.97Å; L307-I318 HydrophobicContact CB-CD1 3.99Å; L307-F323 HydrophobicContact CB-CZ 3.99Å; L307-F323 HydrophobicContact CD1-CE1 3.93Å; L307-F323 HydrophobicContact CD1-CZ 4.13Å
308V98.5Very high96.9Very high2 Ų28.7 Ų8.71%0.0124%0.041CC..Hα-helixtrans-63.2-46.2175.5177.60000110.3T304 M305 H306 R312 I318 F323T304-V308 WeakPolarHBondContact O-CG2 3.24Å; M305-V308 PolarHBondContact O-N 3.1Å; H306-V308 VanDerWaalsContact C-N 3.29Å; H306-V308 PolarHBondContact O-N 3.42Å; V308-R312 VanDerWaalsContact O-CB 3.27Å; V308-R312 WeakPolarHBondContact O-CB 3.21Å; V308-R312 PolarHBondContact O-N 3.39Å; V308-I318 HydrophobicContact CB-CG1 4.39Å; V308-I318 HydrophobicContact CG2-CD1 4.23Å; V308-I318 HydrophobicContact CG2-CG1 3.99Å; V308-F323 HydrophobicContact CG2-CE2 4.17Å
309A98.5Very high97.2Very high0 Ų010.4 Ų10.40%05%0.05CC..Hα-helixtrans-65.1-44.4177.900000112.4M163 M305 H306 R312 A313M163-A309 HydrophobicContact CE-CB 4.49Å; M163-A309 HydrophobicContact SD-CB 4.04Å; M305-A309 PolarHBondContact O-N 3.07Å; H306-A309 PolarHBondContact O-N 3.04Å; A309-R312 PolarHBondContact O-N 3.22Å; A309-A313 PolarHBondContact O-N 3.2Å; A309-A313 VanDerWaalsContact O-N 3.16Å
310M98.6Very high97.4Very high4 Ų410.4 Ų10.42%0.025%0.05CC..Hα-helixtrans-63.4-47.6176.9-71-174.4-67.900111.8P159 T162 M163 L166 H306 L307 R312 A313P159-M310 HydrophobicContact CB-CG 4.13Å; P159-M310 HydrophobicContact CB-SD 4.05Å; P159-M310 HydrophobicContact CG-SD 4.45Å; T162-M310 VanDerWaalsContact CB-SD 3.59Å; T162-M310 HydrophobicContact CG2-CB 3.97Å; T162-M310 HydrophobicContact CG2-CG 3.73Å; T162-M310 HydrophobicContact CG2-SD 3.63Å; M163-M310 HydrophobicContact CG-CG 4.46Å; L166-M310 WeakPolarHBondContact CD1-O 3.25Å; H306-M310 HydrophobicContact CB-CE 4.21Å; H306-M310 WeakPolarHBondContact O-CB 3.26Å; H306-M310 VanDerWaalsContact O-CG 3.25Å; H306-M310 WeakPolarHBondContact O-CG 3.35Å; H306-M310 PolarHBondContact O-N 2.68Å; L307-M310 HydrophobicContact CB-CE 4.46Å; L307-M310 HydrophobicContact CD2-CE 3.75Å; L307-M310 HydrophobicContact CG-CE 4Å; L307-M310 PolarHBondContact O-N 3.03Å; M310-R312 VanDerWaalsContact C-N 3.32Å; M310-R312 PolarHBondContact O-N 2.93Å; M310-A313 WeakPolarHBondContact O-CB 3.46Å; M310-A313 PolarHBondContact O-N 3.16Å
311A98.7Very high97.5Very high2 Ų213.4 Ų13.42%0.0177%0.066CC..Hα-helixtrans-61-42.5178.100000111.2V287 L307 A313 A314 G315 I316 I318V287-A311 HydrophobicContact CG1-CB 3.96Å; V287-A311 HydrophobicContact CG2-CB 4.1Å; L307-A311 WeakPolarHBondContact O-CB 3.4Å; L307-A311 PolarHBondContact O-N 2.97Å; A311-A313 VanDerWaalsContact C-N 3.26Å; A311-A313 PolarHBondContact O-N 3.31Å; A311-A314 CarbonylContact O-C 3.6Å; A311-A314 WeakPolarHBondContact O-CA 3.4Å; A311-A314 WeakPolarHBondContact O-CB 3.22Å; A311-A314 PolarHBondContact O-N 2.84Å; A311-G315 PolarHBondContact O-N 3.47Å; A311-I316 CarbonylContact C-O 3.47Å; A311-I316 HydrophobicContact CB-CB 4.05Å; A311-I316 HydrophobicContact CB-CG2 4.17Å; A311-I316 WeakPolarHBondContact O-CA 3.38Å; A311-I316 WeakPolarHBondContact O-CB 3.36Å; A311-I316 PolarHBondContact O-N 3.42Å; A311-I316 VanDerWaalsContact O-O 3.13Å; A311-I318 HydrophobicContact CB-CD1 4.1Å; A311-I318 HydrophobicContact CB-CG1 3.97Å
312R98.4Very high97.7Very high87 Ų8713.2 Ų13.233%0.3287%0.065SC..Hα-helixtrans-61.1-35.7178.1-173.7171.5-111.1121.13.6112.1V308 A309 M310 A314 G315 I316 Q596 F603V308-R312 VanDerWaalsContact O-CB 3.27Å; V308-R312 WeakPolarHBondContact O-CB 3.21Å; V308-R312 PolarHBondContact O-N 3.39Å; A309-R312 PolarHBondContact O-N 3.22Å; M310-R312 VanDerWaalsContact C-N 3.32Å; M310-R312 PolarHBondContact O-N 2.93Å; R312-A314 PolarHBondContact O-N 3.15Å; R312-G315 PolarHBondContact O-N 2.99Å; R312-I316 WeakPolarHBondContact CA-O 3.41Å; R312-I316 PolarHBondContact N-O 2.74Å; R312-I316 VanDerWaalsContact N-O 3.15Å; R312-Q596 PolarHBondContact NH1-O 2.87Å; R312-F603 HydrophobicContact CB-CD2 4.41Å; R312-F603 HydrophobicContact CG-CD2 4Å
313A98.5Very high97.8Very high1 Ų113.3 Ų13.31%0.0087%0.065CC..Hα-helixtrans-62.9-21.4173.900000113.7Y23 M163 L166 A309 M310 A311 F603Y23-A313 WeakPolarHBondContact CE2-O 3.42Å; M163-A313 HydrophobicContact CB-CB 4.35Å; M163-A313 HydrophobicContact CG-CB 4.29Å; L166-A313 HydrophobicContact CB-CB 3.92Å; L166-A313 HydrophobicContact CD1-CB 3.99Å; A309-A313 PolarHBondContact O-N 3.2Å; A309-A313 VanDerWaalsContact O-N 3.16Å; M310-A313 WeakPolarHBondContact O-CB 3.46Å; M310-A313 PolarHBondContact O-N 3.16Å; A311-A313 VanDerWaalsContact C-N 3.26Å; A311-A313 PolarHBondContact O-N 3.31Å; A313-F603 HydrophobicContact CB-CD1 3.83Å; A313-F603 HydrophobicContact CB-CD2 4.33Å; A313-F603 HydrophobicContact CB-CE1 3.53Å; A313-F603 HydrophobicContact CB-CE2 4.06Å; A313-F603 HydrophobicContact CB-CG 4.22Å; A313-F603 HydrophobicContact CB-CZ 3.64Å
314A98.7Very high97.7Very high0 Ų014.3 Ų14.30%07%0.072CC..THydrogen-bonded Turntrans-96.18.1173.300000113.7R20 Y23 L166 I282 A311 R312 I316R20-A314 VanDerWaalsContact CD-O 3.27Å; R20-A314 WeakPolarHBondContact CD-O 3.45Å; R20-A314 PolarHBondContact NH1-O 2.91Å; Y23-A314 VanDerWaalsContact CD1-O 3.26Å; Y23-A314 WeakPolarHBondContact CD1-O 3.41Å; Y23-A314 HydrophobicContact CE1-CB 4.47Å; L166-A314 HydrophobicContact CD1-CB 4.01Å; L166-A314 HydrophobicContact CD2-CB 3.94Å; L166-A314 HydrophobicContact CG-CB 4.48Å; I282-A314 HydrophobicContact CG2-CB 4.29Å; A311-A314 CarbonylContact O-C 3.6Å; A311-A314 WeakPolarHBondContact O-CA 3.4Å; A311-A314 WeakPolarHBondContact O-CB 3.22Å; A311-A314 PolarHBondContact O-N 2.84Å; R312-A314 PolarHBondContact O-N 3.15Å; A314-I316 VanDerWaalsContact C-N 3.28Å; A314-I316 HydrophobicContact CB-CD1 3.96Å; A314-I316 HydrophobicContact CB-CG1 4.23Å; A314-I316 PolarHBondContact O-N 3.44Å
315G98.5Very high97.7Very high9 Ų915.9 Ų15.99%0.0938%0.08CC..THydrogen-bonded Turntrans73.614.7-173.200000114.4T19 R20 A311 R312T19-G315 CarbonylContact C-O 3.21Å; T19-G315 WeakPolarHBondContact CB-O 3.47Å; T19-G315 PolarHBondContact OG1-O 3.12Å; R20-G315 PolarHBondContact N-O 2.8Å; R20-G315 VanDerWaalsContact N-O 3.16Å; A311-G315 PolarHBondContact O-N 3.47Å; R312-G315 PolarHBondContact O-N 2.99Å
316I98.9Very high97.7Very high0 Ų015.9 Ų15.90%08%0.08CC..  trans-101.1130-177.7-58.6165.7000109.5I12 D283 E284 V287 A311 R312 A314 I318I12-I316 HydrophobicContact CG2-CG2 3.71Å; D283-I316 VanDerWaalsContact C-CD1 3.41Å; E284-I316 HydrophobicContact CG-CD1 4.43Å; E284-I316 HydrophobicContact CG-CG1 4.21Å; E284-I316 HydrophobicContact CG-CG2 4.04Å; V287-I316 HydrophobicContact CG2-CD1 3.76Å; V287-I316 HydrophobicContact CG2-CG2 4.37Å; A311-I316 CarbonylContact C-O 3.47Å; A311-I316 HydrophobicContact CB-CB 4.05Å; A311-I316 HydrophobicContact CB-CG2 4.17Å; A311-I316 WeakPolarHBondContact O-CA 3.38Å; A311-I316 WeakPolarHBondContact O-CB 3.36Å; A311-I316 PolarHBondContact O-N 3.42Å; A311-I316 VanDerWaalsContact O-O 3.13Å; R312-I316 WeakPolarHBondContact CA-O 3.41Å; R312-I316 PolarHBondContact N-O 2.74Å; R312-I316 VanDerWaalsContact N-O 3.15Å; A314-I316 VanDerWaalsContact C-N 3.28Å; A314-I316 HydrophobicContact CB-CD1 3.96Å; A314-I316 HydrophobicContact CB-CG1 4.23Å; A314-I316 PolarHBondContact O-N 3.44Å; I316-I318 HydrophobicContact CG2-CG2 4.32Å
317Q98.6Very high97.6Very high59 Ų5915.9 Ų15.928%0.2768%0.08SC..  trans-107.8109-177.5-58.2-174.815.600110.2R15 S16 T19R15-Q317 HydrophobicContact CG-CB 4.17Å; R15-Q317 PolarHBondContact NE-O 3.24Å; R15-Q317 VanDerWaalsContact NE-O 3.08Å; R15-Q317 PolarHBondContact NH2-O 3.14Å; S16-Q317 PolarHBondContact OG-N 3.08Å; T19-Q317 VanDerWaalsContact CG2-NE2 3.28Å; T19-Q317 PolarHBondContact OG1-NE2 2.99Å
318I98.6Very high97.4Very high10 Ų1019.3 Ų19.35%0.05110%0.099CC..  trans-115.2153.2169.460.3169.2000110.3I12 V287 I291 L307 V308 A311 I316 D322 F323I12-I318 HydrophobicContact CD1-CG2 3.75Å; I12-I318 HydrophobicContact CG1-CG2 3.99Å; I12-I318 HydrophobicContact CG2-CG2 3.89Å; V287-I318 HydrophobicContact CG1-CD1 3.9Å; V287-I318 HydrophobicContact CG1-CG2 3.87Å; I291-I318 HydrophobicContact CD1-CD1 3.94Å; I291-I318 HydrophobicContact CD1-CG2 4.45Å; L307-I318 HydrophobicContact CB-CD1 3.99Å; V308-I318 HydrophobicContact CB-CG1 4.39Å; V308-I318 HydrophobicContact CG2-CD1 4.23Å; V308-I318 HydrophobicContact CG2-CG1 3.99Å; A311-I318 HydrophobicContact CB-CD1 4.1Å; A311-I318 HydrophobicContact CB-CG1 3.97Å; I316-I318 HydrophobicContact CG2-CG2 4.32Å; I318-D322 VanDerWaalsContact CA-OD2 3.31Å; I318-D322 WeakPolarHBondContact CA-OD2 3.49Å; I318-F323 HydrophobicContact CD1-CE2 3.89Å; I318-F323 HydrophobicContact CD1-CZ 3.96Å
319N97.5Very high97.2Very high36 Ų3620.9 Ų20.919%0.19311%0.108CC..  trans-139.8176.6175.971.3-4.6000110.7R15 D321 D322 F323R15-N319 PolarHBondContact NH1-ND2 3.39Å; R15-N319 PolarHBondContact NH1-OD1 3.32Å; N319-D321 PolarHBondContact ND2-OD2 2.83Å; N319-D321 PolarHBondContact O-N 3.3Å; N319-D321 PolarHBondContact OD1-N 3.41Å; N319-D322 PolarHBondContact N-OD2 3.47Å; N319-D322 WeakPolarHBondContact O-CB 3.34Å; N319-D322 PolarHBondContact O-N 2.89Å; N319-D322 VanDerWaalsContact O-N 3.07Å; N319-D322 PolarHBondContact OD1-N 2.62Å; N319-D322 PolarHBondContact OD1-OD2 3.46Å; N319-D322 VanDerWaalsContact OD1-OD2 3.14Å; N319-F323 VanDerWaalsContact O-CD2 3.3Å; N319-F323 WeakPolarHBondContact O-CD2 3.23Å
320W97.5Very high97.2Very high0 Ų020.9 Ų20.90%011%0.108CC..Hα-helixtrans-64.7-24.2-176.5-71.8-13.4000114.1T304 D322 F323 S324 V422 R429 V431 H524 A594 E595T304-W320 PolarHBondContact O-NE1 2.95Å; W320-D322 PolarHBondContact O-N 3.2Å; W320-F323 PolarHBondContact O-N 2.88Å; W320-F323 VanDerWaalsContact O-N 3.15Å; W320-S324 PolarHBondContact O-N 3.1Å; W320-V422 HydrophobicContact CB-CG1 4.1Å; W320-V422 HydrophobicContact CB-CG2 3.69Å; W320-V422 HydrophobicContact CE3-CG1 4.34Å; W320-V422 HydrophobicContact CG-CG2 4.41Å; W320-V422 WeakPolarHBondContact O-CG2 3.49Å; W320-R429 HydrophobicContact CE3-CB 4.03Å; W320-R429 HydrophobicContact CZ3-CB 3.78Å; W320-V431 HydrophobicContact CD2-CG1 3.72Å; W320-V431 HydrophobicContact CE3-CG1 4.1Å; W320-V431 HydrophobicContact CG-CG1 4.19Å; W320-V431 HydrophobicContact CH2-CG1 4.24Å; W320-V431 HydrophobicContact CZ2-CG1 3.86Å; W320-V431 HydrophobicContact CZ3-CG1 4.35Å; W320-H524 HydrophobicContact CH2-CB 3.83Å; W320-H524 WeakPolarHBondContact CH2-O 3.41Å; W320-H524 HydrophobicContact CZ2-CB 3.96Å; W320-A594 HydrophobicContact CH2-CB 4.35Å; W320-A594 HydrophobicContact CZ2-CB 4.22Å; W320-E595 HydrophobicContact CB-CG 4.33Å; W320-E595 WeakPolarHBondContact CB-OE1 3.41Å; W320-E595 HydrophobicContact CD2-CB 3.8Å; W320-E595 HydrophobicContact CD2-CG 3.69Å; W320-E595 HydrophobicContact CE3-CB 3.85Å; W320-E595 HydrophobicContact CE3-CG 3.92Å; W320-E595 HydrophobicContact CG-CB 4.45Å; W320-E595 HydrophobicContact CG-CG 3.86Å; W320-E595 HydrophobicContact CH2-CB 3.94Å; W320-E595 HydrophobicContact CZ2-CB 3.9Å; W320-E595 HydrophobicContact CZ3-CB 3.9Å; W320-E595 HydrophobicContact CZ3-CG 4.48Å; W320-E595 PolarHBondContact N-OE1 2.96Å
321D95.9Very high97.1Very high64 Ų6420.9 Ų20.934%0.34211%0.108SC..Hα-helixtrans-62.4-33.3174.2-50.9-43.4000111.5R11 N319 S324 D325 R429R11-D321 PolarHBondContact NH2-O 2.93Å; N319-D321 PolarHBondContact ND2-OD2 2.83Å; N319-D321 PolarHBondContact O-N 3.3Å; N319-D321 PolarHBondContact OD1-N 3.41Å; D321-S324 PolarHBondContact O-N 3.29Å; D321-D325 VanDerWaalsContact O-CB 3.27Å; D321-D325 WeakPolarHBondContact O-CB 3.37Å; D321-D325 VanDerWaalsContact O-CG 3.3Å; D321-D325 PolarHBondContact O-N 2.83Å; D321-R429 IonicContact OD1-CZ 2.85Å; D321-R429 IonicContact OD1-NH1 2.79Å; D321-R429 PolarHBondContact OD1-NH1 3.3Å; D321-R429 IonicContact OD1-NH2 3.12Å; D321-R429 PolarHBondContact OD1-NH2 2.87Å; D321-R429 IonicContact OD2-NH2 3.71Å
322D97.7Very high96.9Very high0 Ų021 Ų210%011%0.109CC..Hα-helixtrans-68.2-42.1174.4-51.6-46.2000111.8V8 R11 I12 R15 I318 N319 W320 L326V8-D322 HydrophobicContact CG1-CB 3.78Å; R11-D322 IonicContact CZ-OD1 2.74Å; R11-D322 IonicContact NE-OD1 2.86Å; R11-D322 PolarHBondContact NE-OD1 3.21Å; R11-D322 VanDerWaalsContact NE-OD1 3.09Å; R11-D322 IonicContact NH2-OD1 3.51Å; R11-D322 PolarHBondContact NH2-OD1 3.07Å; I12-D322 HydrophobicContact CD1-CB 4.2Å; R15-D322 IonicContact CZ-OD2 2.77Å; R15-D322 IonicContact NH1-OD1 3.78Å; R15-D322 IonicContact NH1-OD2 3.35Å; R15-D322 IonicContact NH2-OD1 3.71Å; R15-D322 PolarHBondContact NH2-OD1 3.34Å; R15-D322 IonicContact NH2-OD2 2.58Å; R15-D322 PolarHBondContact NH2-OD2 3.35Å; I318-D322 VanDerWaalsContact CA-OD2 3.31Å; I318-D322 WeakPolarHBondContact CA-OD2 3.49Å; N319-D322 PolarHBondContact N-OD2 3.47Å; N319-D322 WeakPolarHBondContact O-CB 3.34Å; N319-D322 PolarHBondContact O-N 2.89Å; N319-D322 VanDerWaalsContact O-N 3.07Å; N319-D322 PolarHBondContact OD1-N 2.62Å; N319-D322 PolarHBondContact OD1-OD2 3.46Å; N319-D322 VanDerWaalsContact OD1-OD2 3.14Å; W320-D322 PolarHBondContact O-N 3.2Å; D322-L326 VanDerWaalsContact O-CB 3.29Å; D322-L326 WeakPolarHBondContact O-CB 3.34Å; D322-L326 WeakPolarHBondContact O-CD1 3.37Å; D322-L326 VanDerWaalsContact O-CG 3.23Å; D322-L326 WeakPolarHBondContact O-CG 3.44Å; D322-L326 PolarHBondContact O-N 2.81Å
323F96.8Very high96.8Very high3 Ų316.9 Ų16.91%0.0139%0.094CC..Hα-helixtrans-62.2-44.7175-71.4-97.7000111I291 L294 T304 L307 V308 I318 N319 W320 S327I291-F323 HydrophobicContact CB-CE1 4.44Å; I291-F323 HydrophobicContact CD1-CE1 4.42Å; I291-F323 HydrophobicContact CD1-CE2 4.32Å; I291-F323 HydrophobicContact CD1-CZ 4.19Å; I291-F323 HydrophobicContact CG1-CD1 4.4Å; I291-F323 HydrophobicContact CG1-CE1 3.88Å; I291-F323 HydrophobicContact CG1-CZ 3.99Å; I291-F323 HydrophobicContact CG2-CD1 3.67Å; I291-F323 HydrophobicContact CG2-CE1 3.95Å; I291-F323 HydrophobicContact CG2-CG 4.23Å; L294-F323 HydrophobicContact CD2-CD1 4.06Å; L294-F323 HydrophobicContact CD2-CE1 3.74Å; T304-F323 HydrophobicContact CG2-CD1 4.22Å; T304-F323 HydrophobicContact CG2-CE1 4.35Å; L307-F323 HydrophobicContact CB-CZ 3.99Å; L307-F323 HydrophobicContact CD1-CE1 3.93Å; L307-F323 HydrophobicContact CD1-CZ 4.13Å; V308-F323 HydrophobicContact CG2-CE2 4.17Å; I318-F323 HydrophobicContact CD1-CE2 3.89Å; I318-F323 HydrophobicContact CD1-CZ 3.96Å; N319-F323 VanDerWaalsContact O-CD2 3.3Å; N319-F323 WeakPolarHBondContact O-CD2 3.23Å; W320-F323 PolarHBondContact O-N 2.88Å; W320-F323 VanDerWaalsContact O-N 3.15Å; F323-S327 VanDerWaalsContact O-CB 3.23Å; F323-S327 WeakPolarHBondContact O-CB 3.39Å; F323-S327 PolarHBondContact O-N 2.91Å
324S93.8Very high96.6Very high21 Ų2116.9 Ų16.915%0.1479%0.093CC..Hα-helixtrans-63.7-51.7179.6-168.20000111.5W320 D321 L326 S327 D328W320-S324 PolarHBondContact O-N 3.1Å; D321-S324 PolarHBondContact O-N 3.29Å; S324-L326 VanDerWaalsContact C-N 3.27Å; S324-L326 PolarHBondContact O-N 3.5Å; S324-S327 WeakPolarHBondContact O-CB 3.28Å; S324-S327 PolarHBondContact O-N 3.23Å; S324-S327 VanDerWaalsContact O-N 3.09Å; S324-D328 PolarHBondContact O-N 3.38Å; S324-D328 VanDerWaalsContact O-N 3.17Å
325D95.1Very high96.3Very high33 Ų3321.7 Ų21.718%0.17611%0.111CC..Hα-helixtrans-63.8-32.8-177.8-79.4-26.8000112.6Q4 R7 V8 R11 D321Q4-D325 PolarHBondContact NE2-O 3Å; R7-D325 IonicContact NH2-OD1 3.23Å; R7-D325 IonicContact NH2-OD2 2.63Å; V8-D325 HydrophobicContact CG2-CB 3.59Å; R11-D325 IonicContact CZ-OD2 3.69Å; R11-D325 IonicContact NH1-OD2 3.88Å; R11-D325 PolarHBondContact NH1-OD2 3.32Å; R11-D325 IonicContact NH2-OD2 3.17Å; R11-D325 PolarHBondContact NH2-OD2 3.36Å; D321-D325 VanDerWaalsContact O-CB 3.27Å; D321-D325 WeakPolarHBondContact O-CB 3.37Å; D321-D325 VanDerWaalsContact O-CG 3.3Å; D321-D325 PolarHBondContact O-N 2.83Å
326L97.5Very high96Very high0 Ų021.3 Ų21.30%011%0.107CC..Hα-helixtrans-74.1-39172.7-73.1168.8000111.5L5 V8 V288 I291 L295 D322 S324 D328 V329 V330L5-L326 HydrophobicContact CB-CD2 4.2Å; L5-L326 HydrophobicContact CG-CD2 4.12Å; V8-L326 HydrophobicContact CB-CD2 4.16Å; V8-L326 HydrophobicContact CB-CG 4.23Å; V8-L326 HydrophobicContact CG1-CD1 3.98Å; V8-L326 HydrophobicContact CG1-CD2 4.3Å; V8-L326 HydrophobicContact CG1-CG 3.92Å; V8-L326 HydrophobicContact CG2-CD2 4.34Å; V8-L326 HydrophobicContact CG2-CG 4.25Å; V288-L326 HydrophobicContact CG1-CD1 4.23Å; V288-L326 HydrophobicContact CG1-CD2 4.35Å; I291-L326 HydrophobicContact CB-CD1 3.99Å; I291-L326 HydrophobicContact CD1-CD1 4.19Å; I291-L326 HydrophobicContact CG2-CB 4.44Å; I291-L326 HydrophobicContact CG2-CD1 3.59Å; L295-L326 HydrophobicContact CD1-CB 3.64Å; D322-L326 VanDerWaalsContact O-CB 3.29Å; D322-L326 WeakPolarHBondContact O-CB 3.34Å; D322-L326 WeakPolarHBondContact O-CD1 3.37Å; D322-L326 VanDerWaalsContact O-CG 3.23Å; D322-L326 WeakPolarHBondContact O-CG 3.44Å; D322-L326 PolarHBondContact O-N 2.81Å; S324-L326 VanDerWaalsContact C-N 3.27Å; S324-L326 PolarHBondContact O-N 3.5Å; L326-D328 PolarHBondContact O-N 3.06Å; L326-V329 WeakPolarHBondContact O-CG2 3.4Å; L326-V329 PolarHBondContact O-N 2.88Å; L326-V330 WeakPolarHBondContact O-CB 3.36Å; L326-V330 WeakPolarHBondContact O-CG2 3.42Å; L326-V330 PolarHBondContact O-N 3.04Å
327S95Very high95.5Very high0 Ų022.8 Ų22.80%011%0.113CC..Hα-helixtrans-61.2-28.8179-172.30000112.7F323 S324 V329 H417 G418 T420F323-S327 VanDerWaalsContact O-CB 3.23Å; F323-S327 WeakPolarHBondContact O-CB 3.39Å; F323-S327 PolarHBondContact O-N 2.91Å; S324-S327 WeakPolarHBondContact O-CB 3.28Å; S324-S327 PolarHBondContact O-N 3.23Å; S324-S327 VanDerWaalsContact O-N 3.09Å; S327-V329 PolarHBondContact O-N 2.82Å; S327-H417 VanDerWaalsContact O-CA 3.32Å; S327-H417 WeakPolarHBondContact O-CA 3.43Å; S327-H417 PolarHBondContact O-CD2 3.05Å; S327-H417 VanDerWaalsContact O-CD2 3.23Å; S327-H417 PolarHBondContact OG-CD2 2.79Å; S327-H417 PolarHBondContact OG-CE1 2.66Å; S327-H417 PolarHBondContact OG-ND1 2.91Å; S327-H417 PolarHBondContact OG-NE2 2.95Å; S327-G418 PolarHBondContact O-N 2.89Å; S327-G418 PolarHBondContact OG-N 3.09Å; S327-T420 WeakPolarHBondContact CB-O 3.38Å; S327-T420 PolarHBondContact OG-O 3Å
328D93.1Very high94.8Very high74 Ų7421 Ų2140%0.39611%0.106SC..THydrogen-bonded Turntrans-69.2-16.3175.7-69.4-24.9000113.8S324 L326 H417 K421S324-D328 PolarHBondContact O-N 3.38Å; S324-D328 VanDerWaalsContact O-N 3.17Å; L326-D328 PolarHBondContact O-N 3.06Å; D328-H417 IonicContact OD1-CD2 2.82Å; D328-H417 PolarHBondContact OD1-CD2 3.05Å; D328-H417 IonicContact OD1-NE2 2.66Å; D328-K421 IonicContact OD1-NZ 2.66Å; D328-K421 PolarHBondContact OD1-NZ 3.4Å; D328-K421 VanDerWaalsContact OD1-NZ 3.17Å
329V95.7Very high94.2Very high36 Ų3621.3 Ų21.322%0.21811%0.108CC..THydrogen-bonded Turntrans-123.2-17.5-179.5-64.90000114.8Q4 L326 S327 P331 L365Q4-V329 HydrophobicContact CB-CB 4.41Å; Q4-V329 HydrophobicContact CB-CG1 3.69Å; Q4-V329 HydrophobicContact CB-CG2 4.03Å; Q4-V329 HydrophobicContact CG-CB 4.41Å; Q4-V329 HydrophobicContact CG-CG1 3.7Å; Q4-V329 HydrophobicContact CG-CG2 3.82Å; L326-V329 WeakPolarHBondContact O-CG2 3.4Å; L326-V329 PolarHBondContact O-N 2.88Å; S327-V329 PolarHBondContact O-N 2.82Å; V329-P331 WeakPolarHBondContact O-CD 3.17Å; V329-L365 HydrophobicContact CG2-CD2 4.36Å
330V97.4Very high93.7Very high0 Ų020.4 Ų20.40%011%0.107CC..SBendtrans-90.4112.6175.4178.60000108.6V292 L295 A296 L326 L365 H417 G418V292-V330 HydrophobicContact CB-CG2 4.35Å; V292-V330 HydrophobicContact CG1-CG1 3.98Å; V292-V330 HydrophobicContact CG1-CG2 4.08Å; V292-V330 HydrophobicContact CG2-CG2 3.91Å; L295-V330 HydrophobicContact CB-CB 4.06Å; L295-V330 HydrophobicContact CB-CG1 3.74Å; L295-V330 HydrophobicContact CD1-CB 4.28Å; L295-V330 HydrophobicContact CD1-CG2 4.36Å; A296-V330 HydrophobicContact CB-CG1 3.83Å; L326-V330 WeakPolarHBondContact O-CB 3.36Å; L326-V330 WeakPolarHBondContact O-CG2 3.42Å; L326-V330 PolarHBondContact O-N 3.04Å; V330-L365 HydrophobicContact CG2-CD2 4.31Å; V330-H417 CarbonylContact O-C 3.52Å; V330-G418 WeakPolarHBondContact O-CA 3.45Å; V330-G418 PolarHBondContact O-N 3.18Å
331P96.4Very high93.3Very high3 Ų326.1 Ų26.12%0.01914%0.144CC..  trans-75.8153.4-179.629.6-32.6000112A296 V329 M333 L365 F410 P413 S415A296-P331 VanDerWaalsContact CA-O 3.31Å; A296-P331 WeakPolarHBondContact CA-O 3.49Å; V329-P331 WeakPolarHBondContact O-CD 3.17Å; P331-M333 HydrophobicContact CB-CG 4.36Å; P331-M333 HydrophobicContact CG-CG 3.9Å; P331-M333 HydrophobicContact CG-SD 4.09Å; P331-M333 PolarHBondContact O-N 3.32Å; P331-L365 HydrophobicContact CG-CD1 4.47Å; P331-F410 HydrophobicContact CG-CD2 3.7Å; P331-F410 HydrophobicContact CG-CE2 3.99Å; P331-P413 HydrophobicContact CB-CB 3.45Å; P331-P413 VanDerWaalsContact CB-CB 3.45Å; P331-P413 HydrophobicContact CB-CG 3.78Å; P331-P413 HydrophobicContact CG-CB 4.24Å; P331-S415 CarbonylContact C-O 3.57Å; P331-S415 VanDerWaalsContact CA-O 3.27Å; P331-S415 WeakPolarHBondContact CA-O 3.45Å; P331-S415 VanDerWaalsContact CB-O 3.26Å; P331-S415 WeakPolarHBondContact CB-O 3.37Å
332L95.1Very high93.1Very high6 Ų623.3 Ų23.33%0.03113%0.13CC..BIsolated β-bridgetrans-73.3110167.3-177.266000109.5G298 F414 S415G298-L332 VanDerWaalsContact N-CD1 3.34Å; L332-F414 HydrophobicContact CD2-CB 4.3Å; L332-F414 HydrophobicContact CG-CB 4.38Å; L332-F414 WeakPolarHBondContact O-CB 3.36Å; L332-F414 PolarHBondContact O-N 3.17Å; L332-S415 PolarHBondContact N-O 2.82Å
333M96.3Very high93Very high0 Ų024.3 Ų24.30%014%0.135CC..  trans-110.4-10.8-177.1-53.9-162.6-24.600114.1A296 P331 L356 E359 L360 I407 A408 F410 F414A296-M333 PolarHBondContact O-N 3.25Å; P331-M333 HydrophobicContact CB-CG 4.36Å; P331-M333 HydrophobicContact CG-CG 3.9Å; P331-M333 HydrophobicContact CG-SD 4.09Å; P331-M333 PolarHBondContact O-N 3.32Å; M333-L356 HydrophobicContact CB-CD2 3.74Å; M333-L356 HydrophobicContact CE-CD2 3.42Å; M333-L356 VanDerWaalsContact CE-CD2 3.42Å; M333-E359 HydrophobicContact CE-CB 3.68Å; M333-E359 HydrophobicContact SD-CB 4.39Å; M333-L360 HydrophobicContact CE-CD1 4.32Å; M333-L360 HydrophobicContact CE-CD2 4.02Å; M333-L360 HydrophobicContact CE-CG 3.73Å; M333-L360 HydrophobicContact SD-CD2 3.97Å; M333-L360 HydrophobicContact SD-CG 4.33Å; M333-I407 CarbonylContact O-C 3.59Å; M333-I407 WeakPolarHBondContact O-CA 3.47Å; M333-A408 PolarHBondContact O-N 3.09Å; M333-F410 HydrophobicContact SD-CB 4.25Å; M333-F414 VanDerWaalsContact O-CE2 3.31Å; M333-F414 WeakPolarHBondContact O-CE2 3.44Å
334A95.4Very high92.9Very high0 Ų024.2 Ų24.20%014%0.135CC..BIsolated β-bridgetrans-118.6137174.400000112.4A296 T297 L336 F347 V406A296-A334 PolarHBondContact O-N 3.48Å; A296-A334 VanDerWaalsContact O-N 3.16Å; T297-A334 HydrophobicContact CG2-CB 4.13Å; A334-L336 HydrophobicContact CB-CG 4.29Å; A334-F347 HydrophobicContact CB-CD2 4.5Å; A334-F347 HydrophobicContact CB-CE2 4.27Å; A334-V406 CarbonylContact C-O 3.55Å; A334-V406 WeakPolarHBondContact CA-O 3.19Å
335R91.5Very high93Very high102 Ų10224.1 Ų24.139%0.38513%0.133SC..  trans-115.677.4175.8-94-174.5-177.91734.7111.7V406 F414R335-V406 PolarHBondContact N-O 2.87Å; R335-F414 HydrophobicContact CB-CD2 4.1Å; R335-F414 HydrophobicContact CB-CE2 3.75Å; R335-F414 HydrophobicContact CB-CZ 3.99Å; R335-F414 VanDerWaalsContact CD-CD1 3.46Å; R335-F414 HydrophobicContact CG-CB 4.33Å; R335-F414 HydrophobicContact CG-CD1 4.04Å; R335-F414 HydrophobicContact CG-CD2 3.54Å; R335-F414 HydrophobicContact CG-CE1 4.2Å; R335-F414 HydrophobicContact CG-CE2 3.71Å; R335-F414 HydrophobicContact CG-CG 3.7Å; R335-F414 HydrophobicContact CG-CZ 4.05Å; R335-F414 VanDerWaalsContact CZ-CD1 3.45Å; R335-F414 VanDerWaalsContact NE-CD1 3.32Å
336L91.9Very high93.1Very high0 Ų026.4 Ų26.40%014%0.142CC..BIsolated β-bridgetrans-102.6143.9176.9-48.9-179.2000109.9Y224 A334 P338 N339 G340 A342 I344 F347 V406Y224-L336 HydrophobicContact CD1-CB 4.32Å; Y224-L336 HydrophobicContact CD1-CD1 4.13Å; Y224-L336 HydrophobicContact CD2-CD1 3.83Å; Y224-L336 HydrophobicContact CE2-CD1 4.38Å; Y224-L336 HydrophobicContact CG-CB 4.04Å; Y224-L336 HydrophobicContact CG-CD1 3.73Å; Y224-L336 HydrophobicContact CG-CG 4.48Å; A334-L336 HydrophobicContact CB-CG 4.29Å; L336-P338 CarbonylContact O-C 3.55Å; L336-N339 WeakPolarHBondContact O-CA 3.05Å; L336-N339 WeakPolarHBondContact O-CB 3.37Å; L336-N339 PolarHBondContact O-N 3.02Å; L336-G340 PolarHBondContact O-N 3.19Å; L336-A342 CarbonylContact C-O 3.6Å; L336-A342 WeakPolarHBondContact CA-O 3.4Å; L336-A342 HydrophobicContact CD2-CB 4.43Å; L336-I344 HydrophobicContact CD1-CD1 3.8Å; L336-F347 HydrophobicContact CD1-CB 4.16Å; L336-F347 HydrophobicContact CD1-CD2 4.11Å; L336-F347 HydrophobicContact CD1-CG 4Å; L336-F347 HydrophobicContact CD2-CB 3.48Å; L336-F347 VanDerWaalsContact CD2-CB 3.48Å; L336-F347 HydrophobicContact CD2-CD2 3.92Å; L336-F347 HydrophobicContact CD2-CG 3.96Å; L336-F347 HydrophobicContact CG-CB 4.44Å; L336-F347 HydrophobicContact CG-CD2 4.44Å; L336-V406 HydrophobicContact CD2-CG1 4.01Å
337Y88.8Confident93Very high31 Ų3126.4 Ų26.412%0.12214%0.142CC..THydrogen-bonded Turntrans-54.2123.7174.6173.1-97.9000109.7N187 V191 F223 Y224 G340 A342N187-Y337 HydrophobicContact CB-CD1 3.31Å; N187-Y337 HydrophobicContact CB-CD2 3.64Å; N187-Y337 HydrophobicContact CB-CE1 3.52Å; N187-Y337 HydrophobicContact CB-CE2 3.81Å; N187-Y337 HydrophobicContact CB-CG 3.42Å; N187-Y337 VanDerWaalsContact CB-CG 3.42Å; N187-Y337 VanDerWaalsContact CG-CE1 3.45Å; N187-Y337 VanDerWaalsContact ND2-CD1 3.32Å; N187-Y337 WeakPolarHBondContact ND2-CD1 3.48Å; N187-Y337 WeakPolarHBondContact OD1-CE1 3.2Å; V191-Y337 HydrophobicContact CG2-CE2 4.13Å; V191-Y337 WeakPolarHBondContact CG2-OH 3.16Å; F223-Y337 HydrophobicContact CB-CD1 3.33Å; F223-Y337 HydrophobicContact CB-CE1 3.71Å; F223-Y337 HydrophobicContact CG-CD1 4.31Å; F223-Y337 HydrophobicContact CG-CE1 4.23Å; Y224-Y337 WeakPolarHBondContact CA-O 3.41Å; Y224-Y337 WeakPolarHBondContact CB-O 3.35Å; Y224-Y337 PolarHBondContact N-O 3.24Å; Y337-G340 WeakPolarHBondContact CA-O 3.37Å; Y337-G340 WeakPolarHBondContact CB-O 3.29Å; Y337-G340 PolarHBondContact N-O 2.94Å; Y337-G340 VanDerWaalsContact N-O 3.14Å; Y337-A342 PolarHBondContact N-O 2.84Å
338P84.5Confident93.1Very high21 Ų2128.9 Ų28.914%0.13615%0.154CC..THydrogen-bonded Turncis-89-8.820.938.2-41.8000117.7L336 G340 G514 A515L336-P338 CarbonylContact O-C 3.55Å; P338-G340 VanDerWaalsContact C-N 3.27Å; P338-G340 PolarHBondContact O-N 3.15Å; P338-G514 WeakPolarHBondContact CG-O 3.3Å; P338-A515 WeakPolarHBondContact CB-O 3.41Å
339N85.6Confident93.3Very high18 Ų1828.6 Ų28.610%0.09616%0.162CC..SBendtrans-77.8-10.8-177.3-48-33.3000113.5T297 G298 L336 K433T297-N339 PolarHBondContact O-ND2 3.22Å; G298-N339 PolarHBondContact O-ND2 2.98Å; L336-N339 WeakPolarHBondContact O-CA 3.05Å; L336-N339 WeakPolarHBondContact O-CB 3.37Å; L336-N339 PolarHBondContact O-N 3.02Å; N339-K433 VanDerWaalsContact OD1-CE 3.24Å; N339-K433 WeakPolarHBondContact OD1-CE 3.48Å; N339-K433 PolarHBondContact OD1-NZ 3.42Å
340G87.3Confident93.4Very high16 Ų1627 Ų2717%0.16515%0.152CC..SBendtrans-160.4179.718000000111.2L336 Y337 P338L336-G340 PolarHBondContact O-N 3.19Å; Y337-G340 WeakPolarHBondContact CA-O 3.37Å; Y337-G340 WeakPolarHBondContact CB-O 3.29Å; Y337-G340 PolarHBondContact N-O 2.94Å; Y337-G340 VanDerWaalsContact N-O 3.14Å; P338-G340 VanDerWaalsContact C-N 3.27Å; P338-G340 PolarHBondContact O-N 3.15Å
341P88.1Confident93.4Very high120 Ų12027.3 Ų27.378%0.77916%0.156SC*.SBendtrans-80.6-23.5-179.430.7-34.1000113.8
342A93.1Very high93.4Very high5 Ų527.2 Ų27.24%0.04116%0.155CC..BIsolated β-bridgetrans-70.8147-174.800000112.3L336 Y337 H346 V406L336-A342 CarbonylContact C-O 3.6Å; L336-A342 WeakPolarHBondContact CA-O 3.4Å; L336-A342 HydrophobicContact CD2-CB 4.43Å; Y337-A342 PolarHBondContact N-O 2.84Å; A342-H346 HydrophobicContact CB-CB 4.08Å; A342-V406 HydrophobicContact CB-CG1 3.97Å; A342-V406 HydrophobicContact CB-CG2 3.78Å
343D93.6Very high93.6Very high22 Ų2227 Ų2712%0.11815%0.154CC..  trans-97.5-178.5169.769.917.2000111.2S183 T222 N345 H346 F347S183-D343 VanDerWaalsContact CB-OD2 3.23Å; S183-D343 WeakPolarHBondContact CB-OD2 3.29Å; S183-D343 VanDerWaalsContact OG-CG 3.3Å; S183-D343 PolarHBondContact OG-OD1 2.81Å; S183-D343 PolarHBondContact OG-OD2 3Å; T222-D343 WeakPolarHBondContact O-CB 3.12Å; D343-N345 PolarHBondContact O-N 3.43Å; D343-N345 WeakPolarHBondContact OD1-CB 3.27Å; D343-N345 PolarHBondContact OD1-N 3.44Å; D343-H346 PolarHBondContact O-N 3.47Å; D343-H346 PolarHBondContact OD1-N 3.26Å; D343-F347 PolarHBondContact O-N 3.24Å
344I95.4Very high93.6Very high0 Ų027 Ų270%015%0.154CC..Hα-helixtrans-67.9-21.5-177.1-157.562.9000113.6P180 T222 Y224 N228 F246 L336 F347 Q348P180-I344 HydrophobicContact CB-CG2 3.68Å; P180-I344 HydrophobicContact CG-CG2 3.96Å; T222-I344 WeakPolarHBondContact O-CB 3.31Å; T222-I344 WeakPolarHBondContact O-CG2 3.41Å; T222-I344 PolarHBondContact O-N 3.11Å; Y224-I344 HydrophobicContact CD2-CD1 4.1Å; N228-I344 HydrophobicContact CB-CD1 4.42Å; N228-I344 HydrophobicContact CB-CG1 4.41Å; F246-I344 HydrophobicContact CD1-CD1 4.16Å; F246-I344 HydrophobicContact CD1-CG1 3.38Å; F246-I344 HydrophobicContact CE1-CD1 3.66Å; F246-I344 HydrophobicContact CE1-CG1 3.31Å; F246-I344 HydrophobicContact CE2-CD1 4.28Å; F246-I344 HydrophobicContact CE2-CG1 4.49Å; F246-I344 HydrophobicContact CG-CG1 4.07Å; F246-I344 HydrophobicContact CZ-CD1 3.75Å; F246-I344 HydrophobicContact CZ-CG1 3.92Å; L336-I344 HydrophobicContact CD1-CD1 3.8Å; I344-F347 HydrophobicContact CD1-CB 4.3Å; I344-F347 HydrophobicContact CD1-CD1 3.77Å; I344-F347 HydrophobicContact CD1-CG 4.27Å; I344-F347 WeakPolarHBondContact O-CB 3.48Å; I344-Q348 PolarHBondContact O-N 3.34Å; I344-Q348 VanDerWaalsContact O-N 3.1Å
345N96Very high93.8Very high19 Ų1927.1 Ų27.110%0.10216%0.155CC..Hα-helixtrans-79.2-41.2177.6-58.6-40.2000109.7P180 M181 S183 H248 D343 F347 Q348 A349P180-N345 WeakPolarHBondContact CG-OD1 3.03Å; M181-N345 PolarHBondContact O-ND2 2.85Å; S183-N345 PolarHBondContact N-ND2 3.41Å; S183-N345 VanDerWaalsContact N-ND2 3.12Å; S183-N345 WeakPolarHBondContact OG-CB 3.3Å; S183-N345 PolarHBondContact OG-ND2 3.26Å; S183-N345 VanDerWaalsContact OG-ND2 3.08Å; H248-N345 PolarHBondContact CE1-OD1 3.46Å; D343-N345 PolarHBondContact O-N 3.43Å; D343-N345 WeakPolarHBondContact OD1-CB 3.27Å; D343-N345 PolarHBondContact OD1-N 3.44Å; N345-F347 VanDerWaalsContact C-N 3.31Å; N345-F347 PolarHBondContact O-N 3.29Å; N345-Q348 PolarHBondContact O-N 2.97Å; N345-A349 WeakPolarHBondContact O-CB 3.4Å; N345-A349 PolarHBondContact O-N 3.01Å
346H96.5Very high94.1Very high81 Ų8122.2 Ų22.238%0.37514%0.136SC..Hα-helixtrans-64.3-37.2171.9-169.2-171.5000111.5A342 D343 Q348 A349 A350 D403A342-H346 HydrophobicContact CB-CB 4.08Å; D343-H346 PolarHBondContact O-N 3.47Å; D343-H346 PolarHBondContact OD1-N 3.26Å; H346-Q348 PolarHBondContact O-N 3.23Å; H346-A349 PolarHBondContact O-N 3.01Å; H346-A350 WeakPolarHBondContact O-CB 2.95Å; H346-A350 PolarHBondContact O-N 3.28Å; H346-D403 IonicContact CE1-OD2 3.43Å; H346-D403 IonicContact NE2-OD2 2.75Å
347F97.4Very high94.4Very high0 Ų022.2 Ų22.20%014%0.136CC..Hα-helixtrans-53.2-52.7168.9174.9-111.8000112.6M232 F246 A334 L336 D343 I344 N345 A349 A350 G351 G352 V353 L356 V406 I407M232-F347 HydrophobicContact SD-CE1 3.77Å; M232-F347 HydrophobicContact SD-CZ 4.01Å; F246-F347 HydrophobicContact CD2-CD1 4.46Å; F246-F347 HydrophobicContact CD2-CE1 4.36Å; F246-F347 HydrophobicContact CE2-CD1 4.36Å; F246-F347 HydrophobicContact CE2-CE1 4.03Å; A334-F347 HydrophobicContact CB-CD2 4.5Å; A334-F347 HydrophobicContact CB-CE2 4.27Å; L336-F347 HydrophobicContact CD1-CB 4.16Å; L336-F347 HydrophobicContact CD1-CD2 4.11Å; L336-F347 HydrophobicContact CD1-CG 4Å; L336-F347 HydrophobicContact CD2-CB 3.48Å; L336-F347 VanDerWaalsContact CD2-CB 3.48Å; L336-F347 HydrophobicContact CD2-CD2 3.92Å; L336-F347 HydrophobicContact CD2-CG 3.96Å; L336-F347 HydrophobicContact CG-CB 4.44Å; L336-F347 HydrophobicContact CG-CD2 4.44Å; D343-F347 PolarHBondContact O-N 3.24Å; I344-F347 HydrophobicContact CD1-CB 4.3Å; I344-F347 HydrophobicContact CD1-CD1 3.77Å; I344-F347 HydrophobicContact CD1-CG 4.27Å; I344-F347 WeakPolarHBondContact O-CB 3.48Å; N345-F347 VanDerWaalsContact C-N 3.31Å; N345-F347 PolarHBondContact O-N 3.29Å; F347-A349 VanDerWaalsContact C-N 3.31Å; F347-A349 PolarHBondContact O-N 3.23Å; F347-A350 PolarHBondContact O-N 3.28Å; F347-A350 VanDerWaalsContact O-N 3.17Å; F347-G351 PolarHBondContact O-N 3.5Å; F347-G352 WeakPolarHBondContact O-CA 3.43Å; F347-G352 PolarHBondContact O-N 3.38Å; F347-V353 HydrophobicContact CE1-CG2 4.32Å; F347-L356 HydrophobicContact CE2-CD1 3.65Å; F347-L356 HydrophobicContact CE2-CG 4.14Å; F347-L356 HydrophobicContact CZ-CD1 3.52Å; F347-L356 HydrophobicContact CZ-CG 4.18Å; F347-V406 HydrophobicContact CB-CG1 4.46Å; F347-I407 HydrophobicContact CD2-CD1 3.68Å; F347-I407 HydrophobicContact CD2-CG1 3.73Å; F347-I407 HydrophobicContact CE2-CD1 3.49Å; F347-I407 VanDerWaalsContact CE2-CD1 3.49Å; F347-I407 HydrophobicContact CE2-CG1 3.72Å; F347-I407 HydrophobicContact CZ-CD1 4.33Å
348Q97Very high94.8Very high52 Ų5223.5 Ų23.524%0.24314%0.141CC..Hα-helixtrans-62.5-42.3-178.3-173.862.114.500110.9F246 I344 N345 H346 A350 G351 G352F246-Q348 HydrophobicContact CB-CB 4.23Å; F246-Q348 HydrophobicContact CB-CG 4.09Å; I344-Q348 PolarHBondContact O-N 3.34Å; I344-Q348 VanDerWaalsContact O-N 3.1Å; N345-Q348 PolarHBondContact O-N 2.97Å; H346-Q348 PolarHBondContact O-N 3.23Å; Q348-A350 VanDerWaalsContact C-N 3.31Å; Q348-A350 PolarHBondContact O-N 3.33Å; Q348-G351 PolarHBondContact O-N 3.11Å; Q348-G351 VanDerWaalsContact O-N 3.15Å; Q348-G352 PolarHBondContact O-N 3.1Å
349A97Very high95.4Very high68 Ų6823.5 Ų23.556%0.56214%0.139SC*.Hα-helixtrans-65.5-30.2176.300000113.5N345 H346 F347 G351N345-A349 WeakPolarHBondContact O-CB 3.4Å; N345-A349 PolarHBondContact O-N 3.01Å; H346-A349 PolarHBondContact O-N 3.01Å; F347-A349 VanDerWaalsContact C-N 3.31Å; F347-A349 PolarHBondContact O-N 3.23Å; A349-G351 PolarHBondContact O-N 3.3Å
350A97.7Very high96Very high2 Ų222.7 Ų22.72%0.01714%0.135CC..THydrogen-bonded Turntrans-72.6-7.9175.700000113.4H346 F347 Q348 S401 L402 D403 V406 I407H346-A350 WeakPolarHBondContact O-CB 2.95Å; H346-A350 PolarHBondContact O-N 3.28Å; F347-A350 PolarHBondContact O-N 3.28Å; F347-A350 VanDerWaalsContact O-N 3.17Å; Q348-A350 VanDerWaalsContact C-N 3.31Å; Q348-A350 PolarHBondContact O-N 3.33Å; A350-S401 WeakPolarHBondContact O-CA 3.27Å; A350-L402 PolarHBondContact O-N 3Å; A350-D403 HydrophobicContact CB-CB 4.16Å; A350-V406 HydrophobicContact CB-CB 4Å; A350-V406 HydrophobicContact CB-CG1 4.06Å; A350-I407 HydrophobicContact CB-CD1 4.04Å; A350-I407 HydrophobicContact CB-CG1 4.16Å
351G97.4Very high96.5Very high8 Ų823.6 Ų23.68%0.08214%0.136CC..THydrogen-bonded Turntrans127.7-12.9179.200000113.9F347 Q348 A349 P354F347-G351 PolarHBondContact O-N 3.5Å; Q348-G351 PolarHBondContact O-N 3.11Å; Q348-G351 VanDerWaalsContact O-N 3.15Å; A349-G351 PolarHBondContact O-N 3.3Å; G351-P354 WeakPolarHBondContact O-CD 3.38Å
352G96.9Very high97Very high0 Ų024.5 Ų24.50%013%0.127CC..Hα-helixtrans58.7-150.4167.600000116.3F347 Q348 V355 L356 I407F347-G352 WeakPolarHBondContact O-CA 3.43Å; F347-G352 PolarHBondContact O-N 3.38Å; Q348-G352 PolarHBondContact O-N 3.1Å; G352-V355 PolarHBondContact O-N 2.87Å; G352-L356 PolarHBondContact O-N 3.13Å; G352-I407 VanDerWaalsContact N-CD1 3.29Å
353V97.5Very high97.1Very high1 Ų125.3 Ų25.31%0.00613%0.134CC..Hα-helixtrans-53.8-45178.3171.80000112.7M232 E235 F236 F246 F347 V355 L356 V357M232-V353 HydrophobicContact CE-CG2 4.12Å; M232-V353 HydrophobicContact SD-CG2 3.6Å; M232-V353 VanDerWaalsContact SD-CG2 3.6Å; E235-V353 HydrophobicContact CG-CG1 4.19Å; F236-V353 HydrophobicContact CD2-CG1 4.39Å; F236-V353 HydrophobicContact CE2-CG1 3.9Å; F246-V353 HydrophobicContact CD2-CG2 4.29Å; F246-V353 HydrophobicContact CE2-CG2 3.82Å; F347-V353 HydrophobicContact CE1-CG2 4.32Å; V353-V355 VanDerWaalsContact C-N 3.34Å; V353-V355 PolarHBondContact O-N 2.52Å; V353-L356 PolarHBondContact O-N 3.06Å; V353-L356 VanDerWaalsContact O-N 3.17Å; V353-V357 HydrophobicContact CG1-CG2 3.79Å; V353-V357 WeakPolarHBondContact O-CG2 3.45Å; V353-V357 PolarHBondContact O-N 3.22Å
354P98.1Very high97.4Very high1 Ų124.6 Ų24.61%0.00613%0.132CC..Hα-helixtrans-53.6-45.1-178.8-32.538.1000115.1G351 R358 E384G351-P354 WeakPolarHBondContact O-CD 3.38Å; P354-R358 WeakPolarHBondContact O-CB 3.37Å; P354-R358 PolarHBondContact O-N 3.12Å; P354-R358 VanDerWaalsContact O-N 3.07Å; P354-E384 HydrophobicContact CG-CB 4.5Å
355V98.1Very high97.5Very high2 Ų224.6 Ų24.61%0.01213%0.132CC..Hα-helixtrans-65.5-45.6179.4173.90000110.8G352 V353 R358 E359 A398 I407G352-V355 PolarHBondContact O-N 2.87Å; V353-V355 VanDerWaalsContact C-N 3.34Å; V353-V355 PolarHBondContact O-N 2.52Å; V355-R358 PolarHBondContact O-N 3.07Å; V355-E359 HydrophobicContact CG1-CG 4.43Å; V355-E359 WeakPolarHBondContact O-CB 3.23Å; V355-E359 WeakPolarHBondContact O-CG 3.44Å; V355-E359 PolarHBondContact O-N 2.86Å; V355-A398 HydrophobicContact CG2-CB 3.76Å; V355-A398 VanDerWaalsContact CG2-O 3.31Å; V355-A398 WeakPolarHBondContact CG2-O 3.23Å; V355-I407 HydrophobicContact CB-CG2 4.44Å; V355-I407 HydrophobicContact CG1-CG2 3.8Å
356L97.7Very high97.6Very high0 Ų023.8 Ų23.80%013%0.127CC..Hα-helixtrans-62.1-46.6179.6-73.9-176.8000112.1M232 F236 T297 M333 F347 G352 V353 R358 E359 L360 I407M232-L356 HydrophobicContact CE-CD1 3.97Å; F236-L356 HydrophobicContact CZ-CB 4Å; T297-L356 HydrophobicContact CG2-CD1 3.63Å; M333-L356 HydrophobicContact CB-CD2 3.74Å; M333-L356 HydrophobicContact CE-CD2 3.42Å; M333-L356 VanDerWaalsContact CE-CD2 3.42Å; F347-L356 HydrophobicContact CE2-CD1 3.65Å; F347-L356 HydrophobicContact CE2-CG 4.14Å; F347-L356 HydrophobicContact CZ-CD1 3.52Å; F347-L356 HydrophobicContact CZ-CG 4.18Å; G352-L356 PolarHBondContact O-N 3.13Å; V353-L356 PolarHBondContact O-N 3.06Å; V353-L356 VanDerWaalsContact O-N 3.17Å; L356-R358 VanDerWaalsContact C-N 3.32Å; L356-R358 PolarHBondContact O-N 3.45Å; L356-E359 PolarHBondContact O-N 3.34Å; L356-L360 WeakPolarHBondContact O-CB 3.39Å; L356-L360 WeakPolarHBondContact O-CD1 3.32Å; L356-L360 VanDerWaalsContact O-CG 3.28Å; L356-L360 WeakPolarHBondContact O-CG 3.26Å; L356-L360 PolarHBondContact O-N 3.1Å; L356-I407 HydrophobicContact CD2-CG2 3.75Å; L356-I407 HydrophobicContact CG-CG2 4.24Å
357V98.3Very high97.7Very high0 Ų020.1 Ų20.10%011%0.11CC..Hα-helixtrans-60.5-45.1179.21720000110.1F236 V353 L360 L361 L366 L378 T382F236-V357 HydrophobicContact CD2-CG2 4.22Å; F236-V357 HydrophobicContact CE1-CG2 4.05Å; F236-V357 HydrophobicContact CE2-CG2 3.62Å; F236-V357 HydrophobicContact CZ-CG2 3.52Å; V353-V357 HydrophobicContact CG1-CG2 3.79Å; V353-V357 WeakPolarHBondContact O-CG2 3.45Å; V353-V357 PolarHBondContact O-N 3.22Å; V357-L360 PolarHBondContact O-N 2.7Å; V357-L361 HydrophobicContact CG1-CD1 3.65Å; V357-L361 HydrophobicContact CG1-CG 4.24Å; V357-L361 VanDerWaalsContact O-CB 3.31Å; V357-L361 WeakPolarHBondContact O-CB 3.29Å; V357-L361 VanDerWaalsContact O-CG 3.26Å; V357-L361 WeakPolarHBondContact O-CG 3.45Å; V357-L361 PolarHBondContact O-N 3.33Å; V357-L366 HydrophobicContact CG1-CD1 4.43Å; V357-L378 HydrophobicContact CG1-CG 4.44Å; V357-T382 HydrophobicContact CB-CG2 4.33Å; V357-T382 HydrophobicContact CG1-CG2 3.91Å
358R97.8Very high97.8Very high58 Ų5823 Ų2322%0.21912%0.124CC..Hα-helixtrans-59.7-50.3178.5-172-175.2-54.7-92.2-3.7112.1P354 V355 L356 L361 K362 T382 E396P354-R358 WeakPolarHBondContact O-CB 3.37Å; P354-R358 PolarHBondContact O-N 3.12Å; P354-R358 VanDerWaalsContact O-N 3.07Å; V355-R358 PolarHBondContact O-N 3.07Å; L356-R358 VanDerWaalsContact C-N 3.32Å; L356-R358 PolarHBondContact O-N 3.45Å; R358-L361 PolarHBondContact O-N 3.1Å; R358-K362 VanDerWaalsContact O-CB 3.31Å; R358-K362 WeakPolarHBondContact O-CB 3.24Å; R358-K362 PolarHBondContact O-N 2.77Å; R358-T382 HydrophobicContact CB-CG2 3.99Å; R358-E396 IonicContact CZ-OE1 3.77Å; R358-E396 IonicContact NH1-OE1 3.39Å; R358-E396 PolarHBondContact NH1-OE1 3.44Å; R358-E396 IonicContact NH2-OE1 2.64Å; R358-E396 PolarHBondContact NH2-OE1 2.96Å
359E97.7Very high97.9Very high21 Ų2124.2 Ų24.210%0.09813%0.132CC..Hα-helixtrans-63.4-43-178.7-77.7-68.2116.200111.8M333 V355 L356 K362 A363 S409 F410M333-E359 HydrophobicContact CE-CB 3.68Å; M333-E359 HydrophobicContact SD-CB 4.39Å; V355-E359 HydrophobicContact CG1-CG 4.43Å; V355-E359 WeakPolarHBondContact O-CB 3.23Å; V355-E359 WeakPolarHBondContact O-CG 3.44Å; V355-E359 PolarHBondContact O-N 2.86Å; L356-E359 PolarHBondContact O-N 3.34Å; E359-K362 PolarHBondContact O-N 2.65Å; E359-A363 WeakPolarHBondContact O-CB 3.34Å; E359-A363 PolarHBondContact O-N 2.63Å; E359-S409 WeakPolarHBondContact OE2-CA 3.43Å; E359-S409 WeakPolarHBondContact OE2-CB 3.24Å; E359-F410 PolarHBondContact OE2-N 3.26Å
360L98.2Very high97.9Very high0 Ų021 Ų210%011%0.106CC..Hα-helixtrans-71.1-37179.1-68.1166000112.6F236 V292 A296 M333 L356 V357 A363 G364 L365 L366F236-L360 HydrophobicContact CE1-CD1 3.7Å; F236-L360 HydrophobicContact CZ-CD1 4.21Å; V292-L360 HydrophobicContact CG1-CD1 4.11Å; V292-L360 HydrophobicContact CG1-CD2 4.25Å; A296-L360 HydrophobicContact CB-CD1 3.83Å; A296-L360 HydrophobicContact CB-CD2 4.16Å; M333-L360 HydrophobicContact CE-CD1 4.32Å; M333-L360 HydrophobicContact CE-CD2 4.02Å; M333-L360 HydrophobicContact CE-CG 3.73Å; M333-L360 HydrophobicContact SD-CD2 3.97Å; M333-L360 HydrophobicContact SD-CG 4.33Å; L356-L360 WeakPolarHBondContact O-CB 3.39Å; L356-L360 WeakPolarHBondContact O-CD1 3.32Å; L356-L360 VanDerWaalsContact O-CG 3.28Å; L356-L360 WeakPolarHBondContact O-CG 3.26Å; L356-L360 PolarHBondContact O-N 3.1Å; V357-L360 PolarHBondContact O-N 2.7Å; L360-A363 PolarHBondContact O-N 3.13Å; L360-G364 PolarHBondContact O-N 2.9Å; L360-L365 HydrophobicContact CB-CB 4.37Å; L360-L365 HydrophobicContact CD2-CB 4.01Å; L360-L365 HydrophobicContact CD2-CD1 3.92Å; L360-L365 PolarHBondContact O-N 2.88Å; L360-L366 HydrophobicContact CB-CD1 3.51Å; L360-L366 HydrophobicContact CB-CG 3.76Å; L360-L366 HydrophobicContact CD1-CD1 4.12Å; L360-L366 HydrophobicContact CD1-CG 4.49Å; L360-L366 HydrophobicContact CG-CD1 4.48Å
361L98.1Very high97.9Very high36 Ų3623 Ų2319%0.18812%0.116CC..Hα-helixtrans-63.1-45.8172.3-77.5171.3000111.3V357 R358 A363 G364 L366 E368V357-L361 HydrophobicContact CG1-CD1 3.65Å; V357-L361 HydrophobicContact CG1-CG 4.24Å; V357-L361 VanDerWaalsContact O-CB 3.31Å; V357-L361 WeakPolarHBondContact O-CB 3.29Å; V357-L361 VanDerWaalsContact O-CG 3.26Å; V357-L361 WeakPolarHBondContact O-CG 3.45Å; V357-L361 PolarHBondContact O-N 3.33Å; R358-L361 PolarHBondContact O-N 3.1Å; L361-A363 VanDerWaalsContact C-N 3.26Å; L361-A363 PolarHBondContact O-N 2.88Å; L361-G364 WeakPolarHBondContact O-CA 3.29Å; L361-G364 PolarHBondContact O-N 3.16Å; L361-L366 HydrophobicContact CD2-CB 3.75Å; L361-L366 HydrophobicContact CG-CB 4.21Å; L361-L366 HydrophobicContact CG-CD1 4.27Å; L361-E368 WeakPolarHBondContact CD1-OE2 3.35Å; L361-E368 HydrophobicContact CD2-CB 3.84Å; L361-E368 VanDerWaalsContact CD2-OE2 3.25Å; L361-E368 WeakPolarHBondContact CD2-OE2 3.45Å
362K96.9Very high98Very high138 Ų13822.8 Ų22.860%0.611%0.113SC*.Hα-helixtrans-57.9-40175.7-179.2-169.1176.2-156.70111.7R358 E359 G364 E411R358-K362 VanDerWaalsContact O-CB 3.31Å; R358-K362 WeakPolarHBondContact O-CB 3.24Å; R358-K362 PolarHBondContact O-N 2.77Å; E359-K362 PolarHBondContact O-N 2.65Å; K362-G364 PolarHBondContact O-N 3.27Å; K362-E411 IonicContact NZ-OE1 2.8Å; K362-E411 PolarHBondContact NZ-OE1 3.16Å
363A96.9Very high98Very high23 Ų2322.8 Ų22.819%0.1911%0.113CC..THydrogen-bonded Turntrans-72.7-7.8175.200000113.9E359 L360 L361 L365 F410E359-A363 WeakPolarHBondContact O-CB 3.34Å; E359-A363 PolarHBondContact O-N 2.63Å; L360-A363 PolarHBondContact O-N 3.13Å; L361-A363 VanDerWaalsContact C-N 3.26Å; L361-A363 PolarHBondContact O-N 2.88Å; A363-L365 VanDerWaalsContact C-N 3.28Å; A363-L365 HydrophobicContact CB-CB 4.41Å; A363-L365 HydrophobicContact CB-CD1 3.99Å; A363-L365 HydrophobicContact CB-CG 3.99Å; A363-L365 PolarHBondContact O-N 2.8Å; A363-F410 HydrophobicContact CB-CB 4.24Å; A363-F410 HydrophobicContact CB-CD1 3.77Å; A363-F410 HydrophobicContact CB-CD2 3.43Å; A363-F410 VanDerWaalsContact CB-CD2 3.43Å; A363-F410 HydrophobicContact CB-CE1 3.96Å; A363-F410 HydrophobicContact CB-CE2 3.66Å; A363-F410 HydrophobicContact CB-CG 3.51Å; A363-F410 HydrophobicContact CB-CZ 3.91Å
364G98.1Very high98Very high7 Ų723.9 Ų23.97%0.07212%0.122CC..THydrogen-bonded Turntrans60.739.8-170.900000111.8M1 N2 L360 L361 K362M1-G364 WeakPolarHBondContact CE-O 3.15Å; M1-G364 VanDerWaalsContact SD-C 3.56Å; M1-G364 WeakPolarHBondContact SD-CA 3.39Å; M1-G364 VanDerWaalsContact SD-O 3.42Å; N2-G364 WeakPolarHBondContact CB-O 3.39Å; N2-G364 PolarHBondContact N-O 3.16Å; L360-G364 PolarHBondContact O-N 2.9Å; L361-G364 WeakPolarHBondContact O-CA 3.29Å; L361-G364 PolarHBondContact O-N 3.16Å; K362-G364 PolarHBondContact O-N 3.27Å
365L98.4Very high97.9Very high0 Ų025 Ų250%013%0.134CC..  trans-105.91.9175.9-72176.5000112.9N2 L5 V292 V329 V330 P331 L360 A363 F410N2-L365 HydrophobicContact CB-CD2 3.85Å; L5-L365 HydrophobicContact CD1-CB 4.49Å; L5-L365 HydrophobicContact CD1-CD2 4.45Å; L5-L365 WeakPolarHBondContact CD1-O 3.47Å; V292-L365 WeakPolarHBondContact CG1-O 3.46Å; V292-L365 VanDerWaalsContact CG2-O 3.31Å; V292-L365 WeakPolarHBondContact CG2-O 3.41Å; V329-L365 HydrophobicContact CG2-CD2 4.36Å; V330-L365 HydrophobicContact CG2-CD2 4.31Å; P331-L365 HydrophobicContact CG-CD1 4.47Å; L360-L365 HydrophobicContact CB-CB 4.37Å; L360-L365 HydrophobicContact CD2-CB 4.01Å; L360-L365 HydrophobicContact CD2-CD1 3.92Å; L360-L365 PolarHBondContact O-N 2.88Å; A363-L365 VanDerWaalsContact C-N 3.28Å; A363-L365 HydrophobicContact CB-CB 4.41Å; A363-L365 HydrophobicContact CB-CD1 3.99Å; A363-L365 HydrophobicContact CB-CG 3.99Å; A363-L365 PolarHBondContact O-N 2.8Å; L365-F410 HydrophobicContact CD1-CD2 3.93Å; L365-F410 HydrophobicContact CD1-CE2 3.62Å
366L98.7Very high97.9Very high1 Ų130.6 Ų30.61%0.00516%0.158CC..SBendtrans-128.4143.2169.8-70.3169000109.3F236 N289 V292 V357 L360 L361 E368 L378F236-L366 HydrophobicContact CD1-CD1 4.14Å; F236-L366 HydrophobicContact CD1-CD2 3.93Å; F236-L366 HydrophobicContact CE1-CD1 3.82Å; F236-L366 HydrophobicContact CE1-CD2 4.22Å; N289-L366 HydrophobicContact CB-CD2 3.85Å; N289-L366 WeakPolarHBondContact OD1-CA 3.48Å; V292-L366 HydrophobicContact CB-CD2 3.94Å; V292-L366 HydrophobicContact CG1-CD2 3.73Å; V292-L366 HydrophobicContact CG1-CG 4.3Å; V357-L366 HydrophobicContact CG1-CD1 4.43Å; L360-L366 HydrophobicContact CB-CD1 3.51Å; L360-L366 HydrophobicContact CB-CG 3.76Å; L360-L366 HydrophobicContact CD1-CD1 4.12Å; L360-L366 HydrophobicContact CD1-CG 4.49Å; L360-L366 HydrophobicContact CG-CD1 4.48Å; L361-L366 HydrophobicContact CD2-CB 3.75Å; L361-L366 HydrophobicContact CG-CB 4.21Å; L361-L366 HydrophobicContact CG-CD1 4.27Å; L366-E368 PolarHBondContact O-N 3.1Å; L366-L378 HydrophobicContact CB-CD2 3.87Å; L366-L378 HydrophobicContact CD1-CD2 3.81Å; L366-L378 HydrophobicContact CD2-CD2 4.24Å; L366-L378 HydrophobicContact CG-CD2 4.19Å
367H98.8Very high97.9Very high4 Ų430.8 Ų30.82%0.01916%0.16CC..  trans-74.2113.2167.2-65.5-78.5000108.9L5 T9 K285 N289 V370L5-H367 VanDerWaalsContact CD2-CE1 3.47Å; L5-H367 WeakPolarHBondContact CD2-CE1 3.32Å; L5-H367 WeakPolarHBondContact CD2-NE2 3.34Å; T9-H367 WeakPolarHBondContact CG2-NE2 3.41Å; T9-H367 PolarHBondContact OG1-CE1 3.01Å; T9-H367 PolarHBondContact OG1-NE2 3.36Å; K285-H367 HydrophobicContact CB-CB 3.82Å; K285-H367 HydrophobicContact CD-CB 4.15Å; K285-H367 HydrophobicContact CG-CB 4.26Å; N289-H367 PolarHBondContact ND2-O 3.01Å; N289-H367 PolarHBondContact OD1-N 3.03Å; H367-V370 HydrophobicContact CB-CG1 3.98Å
368E98.4Very high97.9Very high62 Ų6230.8 Ų30.829%0.2916%0.161SC..  trans-74.9-33.5176.2176.452.1-161.400112L361 L366 V370 G377 L378 S379L361-E368 WeakPolarHBondContact CD1-OE2 3.35Å; L361-E368 HydrophobicContact CD2-CB 3.84Å; L361-E368 VanDerWaalsContact CD2-OE2 3.25Å; L361-E368 WeakPolarHBondContact CD2-OE2 3.45Å; L366-E368 PolarHBondContact O-N 3.1Å; E368-V370 PolarHBondContact O-N 3.42Å; E368-G377 VanDerWaalsContact O-CA 3.32Å; E368-G377 WeakPolarHBondContact O-CA 3.48Å; E368-G377 WeakPolarHBondContact OE1-CA 3.49Å; E368-L378 PolarHBondContact O-N 2.93Å; E368-L378 VanDerWaalsContact O-N 3.08Å; E368-L378 PolarHBondContact OE1-N 2.96Å; E368-L378 WeakPolarHBondContact OE2-CA 3.49Å; E368-L378 WeakPolarHBondContact OE2-CB 3.34Å; E368-L378 PolarHBondContact OE2-N 2.89Å; E368-S379 VanDerWaalsContact CD-N 3.28Å; E368-S379 WeakPolarHBondContact OE1-CB 3.5Å; E368-S379 PolarHBondContact OE1-N 3.39Å; E368-S379 PolarHBondContact OE1-OG 2.74Å; E368-S379 PolarHBondContact OE2-N 2.78Å
369D98.4Very high97.9Very high76 Ų7630.6 Ų30.641%0.40617%0.168SC..SBendtrans-83.857-171.562.8-36000112.3K285 F376K285-D369 VanDerWaalsContact NZ-CG 3.31Å; K285-D369 IonicContact NZ-OD1 3.83Å; K285-D369 IonicContact NZ-OD2 2.85Å; K285-D369 PolarHBondContact NZ-OD2 3.22Å; D369-F376 HydrophobicContact CB-CZ 3.9Å
370V98.6Very high97.9Very high2 Ų234.9 Ų34.91%0.01218%0.183CC..  trans-124.1151.9-179.7-64.10000111.8K285 V286 H367 E368 T372 G377 L378K285-V370 HydrophobicContact CB-CG1 3.73Å; K285-V370 HydrophobicContact CD-CG1 4.33Å; V286-V370 HydrophobicContact CG2-CB 3.8Å; V286-V370 HydrophobicContact CG2-CG1 3.83Å; V286-V370 HydrophobicContact CG2-CG2 4.45Å; H367-V370 HydrophobicContact CB-CG1 3.98Å; E368-V370 PolarHBondContact O-N 3.42Å; V370-T372 HydrophobicContact CG2-CG2 4.27Å; V370-G377 PolarHBondContact O-N 3.39Å; V370-L378 HydrophobicContact CG2-CB 3.99Å; V370-L378 HydrophobicContact CG2-CD1 4.33Å
371N98Very high98Very high42 Ų4234.9 Ų34.923%0.22518%0.183CC..EExtended strand (participates in β ladder)trans-81.5143.6168.6-70.9-64.3000110.1M276 M281M276-N371 HydrophobicContact CE-CB 3.87Å; M276-N371 WeakPolarHBondContact CE-OD1 3.14Å; M276-N371 HydrophobicContact SD-CB 3.79Å; M281-N371 HydrophobicContact CG-CB 4.21Å; M281-N371 WeakPolarHBondContact CG-O 3.31Å
372T98.3Very high98Very high4 Ų433.8 Ų33.83%0.02518%0.178CC..EExtended strand (participates in β ladder)trans-137.2169.6175.978.50000109.8V370 A374 G375 L378 Y381V370-T372 HydrophobicContact CG2-CG2 4.27Å; T372-A374 PolarHBondContact O-N 3.23Å; T372-A374 VanDerWaalsContact O-N 3.11Å; T372-A374 PolarHBondContact OG1-N 3.48Å; T372-G375 PolarHBondContact N-O 2.96Å; T372-G375 VanDerWaalsContact N-O 3.13Å; T372-G375 PolarHBondContact O-N 2.84Å; T372-G375 PolarHBondContact OG1-N 3.03Å; T372-G375 PolarHBondContact OG1-O 3.14Å; T372-L378 HydrophobicContact CG2-CD1 4.32Å; T372-Y381 HydrophobicContact CG2-CD2 4.46Å; T372-Y381 HydrophobicContact CG2-CE2 3.71Å
373V97.8Very high98Very high0 Ų029.4 Ų29.40%016%0.161CC..THydrogen-bonded Turntrans-62.1-17.4171.8-59.30000112.6V174 G238 Q240 L241 Q264 M268 M281V174-V373 HydrophobicContact CB-CG1 4.48Å; V174-V373 HydrophobicContact CG2-CB 4.18Å; V174-V373 HydrophobicContact CG2-CG1 3.87Å; G238-V373 WeakPolarHBondContact O-CG1 3.19Å; G238-V373 WeakPolarHBondContact O-CG2 3.27Å; G238-V373 PolarHBondContact O-N 3.1Å; Q240-V373 VanDerWaalsContact O-CG2 3.3Å; Q240-V373 WeakPolarHBondContact O-CG2 3.38Å; L241-V373 HydrophobicContact CD2-CG2 4.44Å; Q264-V373 VanDerWaalsContact CD-O 3.29Å; Q264-V373 WeakPolarHBondContact CG-O 3.41Å; Q264-V373 PolarHBondContact NE2-O 3.48Å; M268-V373 HydrophobicContact CE-CG1 4.32Å; M268-V373 HydrophobicContact SD-CB 4.22Å; M268-V373 HydrophobicContact SD-CG1 4.36Å; M281-V373 HydrophobicContact CE-CG1 4.05Å; M281-V373 HydrophobicContact SD-CG1 3.83Å
374A97Very high98.1Very high24 Ų2430.5 Ų30.520%0.19816%0.162CC..THydrogen-bonded Turntrans-92.83.6175.400000113.5P242 T372 R380 Y381P242-A374 HydrophobicContact CG-CB 3.81Å; T372-A374 PolarHBondContact O-N 3.23Å; T372-A374 VanDerWaalsContact O-N 3.11Å; T372-A374 PolarHBondContact OG1-N 3.48Å; A374-R380 HydrophobicContact CB-CB 4.31Å; A374-R380 WeakPolarHBondContact O-CD 3.44Å; A374-R380 PolarHBondContact O-NE 2.89Å; A374-Y381 HydrophobicContact CB-CE2 4.39Å
375G96Very high98.1Very high25 Ų2530.8 Ų30.826%0.25816%0.163SC..EExtended strand (participates in β ladder)trans103.5-177.3-17300000112.8T372T372-G375 PolarHBondContact N-O 2.96Å; T372-G375 VanDerWaalsContact N-O 3.13Å; T372-G375 PolarHBondContact O-N 2.84Å; T372-G375 PolarHBondContact OG1-N 3.03Å; T372-G375 PolarHBondContact OG1-O 3.14Å
376F97.2Very high98Very high119 Ų11934.4 Ų34.452%0.52218%0.176SC..EExtended strand (participates in β ladder)trans-67.7139.7179.5-172.5-98.4000111.9D369 R380D369-F376 HydrophobicContact CB-CZ 3.9Å; F376-R380 PolarHBondContact O-NE 3.15Å
377G98.2Very high98Very high4 Ų437 Ų374%0.04119%0.19CC..  trans101.5120.5179.400000113.1E368 V370 S379 R380E368-G377 VanDerWaalsContact O-CA 3.32Å; E368-G377 WeakPolarHBondContact O-CA 3.48Å; E368-G377 WeakPolarHBondContact OE1-CA 3.49Å; V370-G377 PolarHBondContact O-N 3.39Å; G377-S379 VanDerWaalsContact C-N 3.27Å; G377-S379 PolarHBondContact O-N 2.88Å; G377-R380 WeakPolarHBondContact O-CG 3.47Å; G377-R380 PolarHBondContact O-N 3.35Å
378L98.4Very high97.9Very high1 Ų139.5 Ų39.51%0.00520%0.204CC..G310 helixtrans-71.6-21.5175.8-165.368.7000112.7F236 V357 L366 E368 V370 T372 R380 Y381F236-L378 WeakPolarHBondContact O-CD1 3.33Å; V357-L378 HydrophobicContact CG1-CG 4.44Å; L366-L378 HydrophobicContact CB-CD2 3.87Å; L366-L378 HydrophobicContact CD1-CD2 3.81Å; L366-L378 HydrophobicContact CD2-CD2 4.24Å; L366-L378 HydrophobicContact CG-CD2 4.19Å; E368-L378 PolarHBondContact O-N 2.93Å; E368-L378 VanDerWaalsContact O-N 3.08Å; E368-L378 PolarHBondContact OE1-N 2.96Å; E368-L378 WeakPolarHBondContact OE2-CA 3.49Å; E368-L378 WeakPolarHBondContact OE2-CB 3.34Å; E368-L378 PolarHBondContact OE2-N 2.89Å; V370-L378 HydrophobicContact CG2-CB 3.99Å; V370-L378 HydrophobicContact CG2-CD1 4.33Å; T372-L378 HydrophobicContact CG2-CD1 4.32Å; L378-R380 PolarHBondContact O-N 3.45Å; L378-Y381 HydrophobicContact CD1-CD2 3.99Å; L378-Y381 HydrophobicContact CD1-CE2 4.5Å; L378-Y381 HydrophobicContact CD1-CG 4.48Å; L378-Y381 WeakPolarHBondContact O-CB 3.27Å; L378-Y381 PolarHBondContact O-N 3.06Å
379S98.1Very high97.8Very high53 Ų5344.2 Ų44.237%0.37123%0.231SC..G310 helixtrans-55.9-20.4174.5540000113.3E368 G377 Y381 T382E368-S379 VanDerWaalsContact CD-N 3.28Å; E368-S379 WeakPolarHBondContact OE1-CB 3.5Å; E368-S379 PolarHBondContact OE1-N 3.39Å; E368-S379 PolarHBondContact OE1-OG 2.74Å; E368-S379 PolarHBondContact OE2-N 2.78Å; G377-S379 VanDerWaalsContact C-N 3.27Å; G377-S379 PolarHBondContact O-N 2.88Å; S379-Y381 PolarHBondContact O-N 3.14Å; S379-Y381 VanDerWaalsContact O-N 3.1Å; S379-T382 WeakPolarHBondContact O-CB 3.31Å; S379-T382 PolarHBondContact O-N 2.98Å; S379-T382 PolarHBondContact O-OG1 2.97Å
380R98.2Very high97.6Very high111 Ų11143.5 Ų43.542%0.41924%0.241SC..G310 helixtrans-58.3-22.2170.2-64.2-179.9179.4-81-4.3113.5A374 F376 G377 L378 T382 L383A374-R380 HydrophobicContact CB-CB 4.31Å; A374-R380 WeakPolarHBondContact O-CD 3.44Å; A374-R380 PolarHBondContact O-NE 2.89Å; F376-R380 PolarHBondContact O-NE 3.15Å; G377-R380 WeakPolarHBondContact O-CG 3.47Å; G377-R380 PolarHBondContact O-N 3.35Å; L378-R380 PolarHBondContact O-N 3.45Å; R380-T382 VanDerWaalsContact C-N 3.28Å; R380-L383 WeakPolarHBondContact O-CB 3.15Å; R380-L383 WeakPolarHBondContact O-CG 3.26Å; R380-L383 PolarHBondContact O-N 3.41Å
381Y98.6Very high97.5Very high1 Ų150.7 Ų50.70%0.00428%0.275CS..G310 helixtrans-86.96.5176.8-68-100.8000113.2E235 G238 Q240 P242 T372 A374 L378 S379 L383E235-Y381 HydrophobicContact CG-CD1 3.61Å; E235-Y381 HydrophobicContact CG-CE1 3.82Å; E235-Y381 WeakPolarHBondContact O-CD1 3.24Å; E235-Y381 VanDerWaalsContact O-CE1 3.23Å; E235-Y381 WeakPolarHBondContact O-CE1 2.93Å; G238-Y381 WeakPolarHBondContact CA-OH 3.44Å; G238-Y381 PolarHBondContact O-OH 2.98Å; Q240-Y381 VanDerWaalsContact O-CE1 3.32Å; Q240-Y381 WeakPolarHBondContact O-CE1 3.4Å; Q240-Y381 PolarHBondContact O-OH 3.26Å; P242-Y381 HydrophobicContact CB-CD1 4.11Å; P242-Y381 HydrophobicContact CB-CE1 4.35Å; P242-Y381 HydrophobicContact CB-CG 4.43Å; P242-Y381 HydrophobicContact CG-CD1 4.09Å; P242-Y381 HydrophobicContact CG-CD2 4.34Å; P242-Y381 HydrophobicContact CG-CE1 3.97Å; P242-Y381 HydrophobicContact CG-CE2 4.19Å; P242-Y381 HydrophobicContact CG-CG 4.28Å; T372-Y381 HydrophobicContact CG2-CD2 4.46Å; T372-Y381 HydrophobicContact CG2-CE2 3.71Å; A374-Y381 HydrophobicContact CB-CE2 4.39Å; L378-Y381 HydrophobicContact CD1-CD2 3.99Å; L378-Y381 HydrophobicContact CD1-CE2 4.5Å; L378-Y381 HydrophobicContact CD1-CG 4.48Å; L378-Y381 WeakPolarHBondContact O-CB 3.27Å; L378-Y381 PolarHBondContact O-N 3.06Å; S379-Y381 PolarHBondContact O-N 3.14Å; S379-Y381 VanDerWaalsContact O-N 3.1Å; Y381-L383 VanDerWaalsContact C-N 3.3Å
382T98.4Very high97.5Very high13 Ų1350.4 Ų50.48%0.0827%0.273CS..G310 helixtrans-86.6-3.416171.90000112.7V357 R358 S379 R380 G397V357-T382 HydrophobicContact CB-CG2 4.33Å; V357-T382 HydrophobicContact CG1-CG2 3.91Å; R358-T382 HydrophobicContact CB-CG2 3.99Å; S379-T382 WeakPolarHBondContact O-CB 3.31Å; S379-T382 PolarHBondContact O-N 2.98Å; S379-T382 PolarHBondContact O-OG1 2.97Å; R380-T382 VanDerWaalsContact C-N 3.28Å; T382-G397 WeakPolarHBondContact O-CA 3.38Å; T382-G397 PolarHBondContact O-N 3.31Å
383L98.3Very high97.5Very high46 Ų4653.5 Ų53.524%0.24129%0.289CS..EExtended strand (participates in β ladder)trans-88.2148.8174.8-56177.4000110.8R380 Y381 W394 R395 E396R380-L383 WeakPolarHBondContact O-CB 3.15Å; R380-L383 WeakPolarHBondContact O-CG 3.26Å; R380-L383 PolarHBondContact O-N 3.41Å; Y381-L383 VanDerWaalsContact C-N 3.3Å; L383-W394 HydrophobicContact CB-CB 4.28Å; L383-W394 HydrophobicContact CD1-CB 4.28Å; L383-R395 CarbonylContact C-O 3.52Å; L383-R395 VanDerWaalsContact CA-O 3.27Å; L383-R395 WeakPolarHBondContact CA-O 3.05Å; L383-E396 WeakPolarHBondContact CD2-OE2 3.33Å
384E97Very high97.5Very high45 Ų4557.5 Ų57.521%0.2130%0.304CS..EExtended strand (participates in β ladder)trans-116.2138.8172.766.8178.2-165.500111.6P354 W394 R395P354-E384 HydrophobicContact CG-CB 4.5Å; E384-W394 WeakPolarHBondContact O-CA 3.45Å; E384-R395 HydrophobicContact CG-CG 3.71Å; E384-R395 PolarHBondContact N-O 2.95Å; E384-R395 PolarHBondContact O-N 3.34Å; E384-R395 IonicContact OE1-CZ 3.54Å; E384-R395 IonicContact OE1-NE 3.21Å; E384-R395 PolarHBondContact OE1-NE 3.37Å; E384-R395 IonicContact OE1-NH2 3.13Å; E384-R395 PolarHBondContact OE1-NH2 3.29Å
385P98.3Very high97.5Very high13 Ų1362 Ų628%0.08432%0.316CS..EExtended strand (participates in β ladder)trans-77.8143.8175.832.4-33.9000110.4P242 L253 L257 L392 D393P242-P385 WeakPolarHBondContact O-CD 3.39Å; L253-P385 HydrophobicContact CD1-CB 4.29Å; L253-P385 HydrophobicContact CD2-CG 4.49Å; L257-P385 HydrophobicContact CD1-CB 4.4Å; L257-P385 HydrophobicContact CD1-CG 4.05Å; L257-P385 HydrophobicContact CD2-CB 3.86Å; L257-P385 HydrophobicContact CD2-CG 4.14Å; L257-P385 HydrophobicContact CG-CB 4.42Å; P385-L392 HydrophobicContact CB-CD1 3.92Å; P385-D393 WeakPolarHBondContact CA-O 3.27Å
386W97.9Very high97.6Very high77 Ų7765.2 Ų65.229%0.29233%0.325SS..EExtended strand (participates in β ladder)trans-149.8167.2174.773.6-60.2000110.9N388 D393 R395W386-N388 HydrophobicContact CD2-CB 4.33Å; W386-N388 HydrophobicContact CE3-CB 4.46Å; W386-N388 HydrophobicContact CH2-CB 3.65Å; W386-N388 HydrophobicContact CZ2-CB 3.48Å; W386-N388 VanDerWaalsContact CZ2-CB 3.48Å; W386-N388 HydrophobicContact CZ3-CB 4.15Å; W386-D393 VanDerWaalsContact CD1-O 3.26Å; W386-D393 PolarHBondContact N-O 3.04Å; W386-D393 PolarHBondContact O-N 3.47Å; W386-R395 HydrophobicContact CG-CG 4.34Å
387L98.2Very high97.6Very high56 Ų5659.8 Ų59.829%0.29330%0.302SS..EExtended strand (participates in β ladder)trans-98.2103.6173.4-63.6-177.2000110P252 L253 A256 N389 E391P252-L387 HydrophobicContact CB-CD1 3.88Å; L253-L387 HydrophobicContact CB-CG 4.35Å; L253-L387 HydrophobicContact CD1-CD2 3.9Å; L253-L387 HydrophobicContact CD1-CG 3.99Å; A256-L387 HydrophobicContact CB-CD2 3.76Å; L387-N389 PolarHBondContact O-N 3.21Å; L387-E391 CarbonylContact C-O 3.58Å; L387-E391 WeakPolarHBondContact CA-O 3.42Å
388N97Very high97.5Very high56 Ų5661 Ų6130%0.29931%0.311SS..EExtended strand (participates in β ladder)trans-85.6101.9172.8-172.51.3000109W386 G390 E391 D393W386-N388 HydrophobicContact CD2-CB 4.33Å; W386-N388 HydrophobicContact CE3-CB 4.46Å; W386-N388 HydrophobicContact CH2-CB 3.65Å; W386-N388 HydrophobicContact CZ2-CB 3.48Å; W386-N388 VanDerWaalsContact CZ2-CB 3.48Å; W386-N388 HydrophobicContact CZ3-CB 4.15Å; N388-G390 PolarHBondContact O-N 3.06Å; N388-E391 PolarHBondContact N-O 3.34Å; N388-E391 PolarHBondContact O-N 3.09Å; N388-D393 HydrophobicContact CB-CB 3.97Å; N388-D393 PolarHBondContact ND2-OD2 2.89Å
389N95.3Very high97.3Very high161 Ų16167.6 Ų67.686%0.86134%0.342SS*.THydrogen-bonded Turntrans53.335.6-174.7-56.9-46.7000113.7L387 E391L387-N389 PolarHBondContact O-N 3.21Å; N389-E391 VanDerWaalsContact C-N 3.34Å
390G94.1Very high97.2Very high60 Ų6072.5 Ų72.562%0.61936%0.357SS*.THydrogen-bonded Turntrans88.1-7.2-179.600000114.9N388N388-G390 PolarHBondContact O-N 3.06Å
391E96.7Very high97.2Very high154 Ų15468.6 Ų68.672%0.7235%0.347SS*.EExtended strand (participates in β ladder)trans-97140.2174.3-63.6-172.3171.400110.9L387 N388 N389 D393L387-E391 CarbonylContact C-O 3.58Å; L387-E391 WeakPolarHBondContact CA-O 3.42Å; N388-E391 PolarHBondContact N-O 3.34Å; N388-E391 PolarHBondContact O-N 3.09Å; N389-E391 VanDerWaalsContact C-N 3.34Å; E391-D393 PolarHBondContact O-N 3.37Å
392L98.5Very high97.1Very high36 Ų3674.9 Ų74.919%0.18838%0.379CS..EExtended strand (participates in β ladder)trans-68.1127.4176.2179.468.3000110.3L253 A256 L257 A260 P385 W394L253-L392 HydrophobicContact CD1-CD1 3.58Å; A256-L392 HydrophobicContact CB-CB 4.12Å; L257-L392 HydrophobicContact CD2-CD1 4.17Å; L257-L392 HydrophobicContact CD2-CD2 4.21Å; L257-L392 HydrophobicContact CG-CD1 4.29Å; A260-L392 HydrophobicContact CB-CD2 3.34Å; P385-L392 HydrophobicContact CB-CD1 3.92Å; L392-W394 HydrophobicContact CD2-CH2 3.33Å; L392-W394 HydrophobicContact CD2-CZ2 3.89Å; L392-W394 HydrophobicContact CD2-CZ3 3.87Å; L392-W394 HydrophobicContact CG-CE3 4.49Å; L392-W394 HydrophobicContact CG-CH2 3.83Å; L392-W394 HydrophobicContact CG-CZ2 4.35Å; L392-W394 HydrophobicContact CG-CZ3 3.89Å
393D98.3Very high97.1Very high68 Ų6876.2 Ų76.236%0.36439%0.386SS..EExtended strand (participates in β ladder)trans-139.3166174.2-164.25.7000109.8P385 W386 N388 E391P385-D393 WeakPolarHBondContact CA-O 3.27Å; W386-D393 VanDerWaalsContact CD1-O 3.26Å; W386-D393 PolarHBondContact N-O 3.04Å; W386-D393 PolarHBondContact O-N 3.47Å; N388-D393 HydrophobicContact CB-CB 3.97Å; N388-D393 PolarHBondContact ND2-OD2 2.89Å; E391-D393 PolarHBondContact O-N 3.37Å
394W98.4Very high97Very high85 Ų8578 Ų7832%0.32240%0.403SS..EExtended strand (participates in β ladder)trans-118.6132.6175.5-75.4-97.6000109.8L241 P242 L257 A260 L383 E384 L392L241-W394 HydrophobicContact CD1-CZ2 4.39Å; P242-W394 PolarHBondContact O-NE1 3.34Å; L257-W394 HydrophobicContact CD2-CZ2 4.34Å; A260-W394 HydrophobicContact CB-CH2 4.35Å; L383-W394 HydrophobicContact CB-CB 4.28Å; L383-W394 HydrophobicContact CD1-CB 4.28Å; E384-W394 WeakPolarHBondContact O-CA 3.45Å; L392-W394 HydrophobicContact CD2-CH2 3.33Å; L392-W394 HydrophobicContact CD2-CZ2 3.89Å; L392-W394 HydrophobicContact CD2-CZ3 3.87Å; L392-W394 HydrophobicContact CG-CE3 4.49Å; L392-W394 HydrophobicContact CG-CH2 3.83Å; L392-W394 HydrophobicContact CG-CZ2 4.35Å; L392-W394 HydrophobicContact CG-CZ3 3.89Å
395R97.4Very high96.9Very high118 Ų11881.2 Ų81.245%0.44542%0.421SS..EExtended strand (participates in β ladder)trans-123.2167.2174.967.2-176-171.7-168.91.7110.3L383 E384 W386 G397L383-R395 CarbonylContact C-O 3.52Å; L383-R395 VanDerWaalsContact CA-O 3.27Å; L383-R395 WeakPolarHBondContact CA-O 3.05Å; E384-R395 HydrophobicContact CG-CG 3.71Å; E384-R395 PolarHBondContact N-O 2.95Å; E384-R395 PolarHBondContact O-N 3.34Å; E384-R395 IonicContact OE1-CZ 3.54Å; E384-R395 IonicContact OE1-NE 3.21Å; E384-R395 PolarHBondContact OE1-NE 3.37Å; E384-R395 IonicContact OE1-NH2 3.13Å; E384-R395 PolarHBondContact OE1-NH2 3.29Å; W386-R395 HydrophobicContact CG-CG 4.34Å; R395-G397 PolarHBondContact O-N 3.44Å
396E97.8Very high96.9Very high93 Ų9380.8 Ų80.844%0.43542%0.419SS..EExtended strand (participates in β ladder)trans-59.2125.1172.7-163.267-174.300109.6R358 L383R358-E396 IonicContact CZ-OE1 3.77Å; R358-E396 IonicContact NH1-OE1 3.39Å; R358-E396 PolarHBondContact NH1-OE1 3.44Å; R358-E396 IonicContact NH2-OE1 2.64Å; R358-E396 PolarHBondContact NH2-OE1 2.96Å; L383-E396 WeakPolarHBondContact CD2-OE2 3.33Å
397G96.5Very high96.9Very high5 Ų577.1 Ų77.15%0.05241%0.405CS..  trans-71.7177.3172.100000111.5T382 R395 E399T382-G397 WeakPolarHBondContact O-CA 3.38Å; T382-G397 PolarHBondContact O-N 3.31Å; R395-G397 PolarHBondContact O-N 3.44Å; G397-E399 PolarHBondContact O-N 3.04Å
398A95.7Very high96.8Very high28 Ų2874.7 Ų74.723%0.23139%0.392CS..  trans-54.2132.4179.200000112.2V355V355-A398 HydrophobicContact CG2-CB 3.76Å; V355-A398 VanDerWaalsContact CG2-O 3.31Å; V355-A398 WeakPolarHBondContact CG2-O 3.23Å
399E94.9Very high96.7Very high141 Ų14173.9 Ų73.966%0.65939%0.391SS*.SBendtrans-76.4-26.3178.6-67.9-175.6171.800112.8G397G397-E399 PolarHBondContact O-N 3.04Å
400K96Very high96.7Very high155 Ų15569.4 Ų69.467%0.67436%0.364SS*.SBendtrans-143.3157.2-17963.8-177.9179.3-177.70109.9L402K400-L402 PolarHBondContact O-N 3.16Å
401S97.6Very high96.7Very high30 Ų3071.6 Ų71.621%0.2136%0.358CS..  trans-58.5135.9173.4-178.70000111.6A350 D403 I407A350-S401 WeakPolarHBondContact O-CA 3.27Å; S401-D403 PolarHBondContact OG-N 3.17Å; S401-D403 VanDerWaalsContact OG-N 3.17Å; S401-D403 PolarHBondContact OG-O 2.77Å; S401-I407 WeakPolarHBondContact CB-O 3.37Å; S401-I407 PolarHBondContact OG-O 2.99Å
402L97.4Very high96.7Very high132 Ų13271.9 Ų71.969%0.69136%0.36SS*.SBendtrans-85.7-15.8170.9-59.6179.6000112.1A350 K400A350-L402 PolarHBondContact O-N 3Å; K400-L402 PolarHBondContact O-N 3.16Å
403D97.7Very high96.6Very high41 Ų4171 Ų7122%0.21936%0.356CS..  trans-141.7102.8170.7-172.9-7.3000110.4H346 A350 S401 N405 V406 I407H346-D403 IonicContact CE1-OD2 3.43Å; H346-D403 IonicContact NE2-OD2 2.75Å; A350-D403 HydrophobicContact CB-CB 4.16Å; S401-D403 PolarHBondContact OG-N 3.17Å; S401-D403 VanDerWaalsContact OG-N 3.17Å; S401-D403 PolarHBondContact OG-O 2.77Å; D403-N405 PolarHBondContact O-N 3.28Å; D403-N405 VanDerWaalsContact O-N 3.13Å; D403-N405 VanDerWaalsContact OD1-CB 3.26Å; D403-N405 WeakPolarHBondContact OD1-CB 3.34Å; D403-N405 PolarHBondContact OD1-N 3.26Å; D403-N405 PolarHBondContact OD1-ND2 2.98Å; D403-V406 HydrophobicContact CB-CB 4.39Å; D403-V406 HydrophobicContact CB-CG2 4.17Å; D403-V406 PolarHBondContact O-N 3.3Å; D403-V406 WeakPolarHBondContact OD2-CG2 3.33Å; D403-I407 PolarHBondContact O-N 3.4Å
404S96.3Very high96.3Very high85 Ų8569.8 Ų69.859%0.59435%0.348SS*.THydrogen-bonded Turntrans-66.7-9.9179.457.40000114V406 I407 F414S404-V406 VanDerWaalsContact C-N 3.33Å; S404-I407 WeakPolarHBondContact CA-O 3.23Å; S404-F414 WeakPolarHBondContact O-CE1 3.5Å; S404-F414 VanDerWaalsContact O-CZ 3.23Å; S404-F414 WeakPolarHBondContact O-CZ 3.26Å
405N95.9Very high96Very high112 Ų11268 Ų6860%0.59935%0.348SS*.THydrogen-bonded Turntrans-81.8-14.8171.1-55.8-68.6000112.8D403 F414D403-N405 PolarHBondContact O-N 3.28Å; D403-N405 VanDerWaalsContact O-N 3.13Å; D403-N405 VanDerWaalsContact OD1-CB 3.26Å; D403-N405 WeakPolarHBondContact OD1-CB 3.34Å; D403-N405 PolarHBondContact OD1-N 3.26Å; D403-N405 PolarHBondContact OD1-ND2 2.98Å; N405-F414 VanDerWaalsContact C-CZ 3.46Å; N405-F414 VanDerWaalsContact O-CZ 3.31Å; N405-F414 WeakPolarHBondContact O-CZ 3.41Å
406V96.9Very high95.8Very high4 Ų469.1 Ų69.12%0.02436%0.358CS..THydrogen-bonded Turntrans-107.3-49179.4-177.10000111.2A334 R335 L336 A342 F347 A350 D403 S404A334-V406 CarbonylContact C-O 3.55Å; A334-V406 WeakPolarHBondContact CA-O 3.19Å; R335-V406 PolarHBondContact N-O 2.87Å; L336-V406 HydrophobicContact CD2-CG1 4.01Å; A342-V406 HydrophobicContact CB-CG1 3.97Å; A342-V406 HydrophobicContact CB-CG2 3.78Å; F347-V406 HydrophobicContact CB-CG1 4.46Å; A350-V406 HydrophobicContact CB-CB 4Å; A350-V406 HydrophobicContact CB-CG1 4.06Å; D403-V406 HydrophobicContact CB-CB 4.39Å; D403-V406 HydrophobicContact CB-CG2 4.17Å; D403-V406 PolarHBondContact O-N 3.3Å; D403-V406 WeakPolarHBondContact OD2-CG2 3.33Å; S404-V406 VanDerWaalsContact C-N 3.33Å
407I97.7Very high95.4Very high0 Ų066.2 Ų66.20%034%0.344CS..BIsolated β-bridgetrans-122.6112.4176.1-52.8177.5000108.6M333 F347 A350 G352 V355 L356 S401 D403 S404M333-I407 CarbonylContact O-C 3.59Å; M333-I407 WeakPolarHBondContact O-CA 3.47Å; F347-I407 HydrophobicContact CD2-CD1 3.68Å; F347-I407 HydrophobicContact CD2-CG1 3.73Å; F347-I407 HydrophobicContact CE2-CD1 3.49Å; F347-I407 VanDerWaalsContact CE2-CD1 3.49Å; F347-I407 HydrophobicContact CE2-CG1 3.72Å; F347-I407 HydrophobicContact CZ-CD1 4.33Å; A350-I407 HydrophobicContact CB-CD1 4.04Å; A350-I407 HydrophobicContact CB-CG1 4.16Å; G352-I407 VanDerWaalsContact N-CD1 3.29Å; V355-I407 HydrophobicContact CB-CG2 4.44Å; V355-I407 HydrophobicContact CG1-CG2 3.8Å; L356-I407 HydrophobicContact CD2-CG2 3.75Å; L356-I407 HydrophobicContact CG-CG2 4.24Å; S401-I407 WeakPolarHBondContact CB-O 3.37Å; S401-I407 PolarHBondContact OG-O 2.99Å; D403-I407 PolarHBondContact O-N 3.4Å; S404-I407 WeakPolarHBondContact CA-O 3.23Å
408A96.6Very high94.9Very high4 Ų466 Ų663%0.03334%0.342CS..  trans-84.2161.6175.800000111.7M333 Q412 F414M333-A408 PolarHBondContact O-N 3.09Å; A408-Q412 WeakPolarHBondContact CB-O 3.31Å; A408-F414 HydrophobicContact CB-CD1 4.38Å; A408-F414 HydrophobicContact CB-CD2 3.88Å; A408-F414 HydrophobicContact CB-CE1 4.19Å; A408-F414 HydrophobicContact CB-CE2 3.68Å; A408-F414 HydrophobicContact CB-CG 4.24Å; A408-F414 HydrophobicContact CB-CZ 3.84Å
409S96.1Very high94.4Very high39 Ų3964.7 Ų64.727%0.27333%0.332SS..  trans-82.8163.6167.488.40000110.7E359 E411 Q412E359-S409 WeakPolarHBondContact OE2-CA 3.43Å; E359-S409 WeakPolarHBondContact OE2-CB 3.24Å; S409-E411 VanDerWaalsContact C-N 3.26Å; S409-E411 WeakPolarHBondContact CB-OE2 3.32Å; S409-E411 PolarHBondContact O-N 3.04Å; S409-E411 PolarHBondContact OG-N 3.26Å; S409-E411 PolarHBondContact OG-OE2 3.25Å; S409-Q412 CarbonylContact O-C 3.44Å; S409-Q412 VanDerWaalsContact O-C 3.31Å; S409-Q412 PolarHBondContact O-N 3.12Å; S409-Q412 PolarHBondContact OG-N 3.39Å
410F93.7Very high94.1Very high68 Ų6858.2 Ų58.230%0.29830%0.302SS..SBendtrans-61.6-34.5174.3171.8-100.5000112.3P331 M333 E359 A363 L365 P413P331-F410 HydrophobicContact CG-CD2 3.7Å; P331-F410 HydrophobicContact CG-CE2 3.99Å; M333-F410 HydrophobicContact SD-CB 4.25Å; E359-F410 PolarHBondContact OE2-N 3.26Å; A363-F410 HydrophobicContact CB-CB 4.24Å; A363-F410 HydrophobicContact CB-CD1 3.77Å; A363-F410 HydrophobicContact CB-CD2 3.43Å; A363-F410 VanDerWaalsContact CB-CD2 3.43Å; A363-F410 HydrophobicContact CB-CE1 3.96Å; A363-F410 HydrophobicContact CB-CE2 3.66Å; A363-F410 HydrophobicContact CB-CG 3.51Å; A363-F410 HydrophobicContact CB-CZ 3.91Å; L365-F410 HydrophobicContact CD1-CD2 3.93Å; L365-F410 HydrophobicContact CD1-CE2 3.62Å; F410-P413 WeakPolarHBondContact O-CD 3.47Å
411E94.8Very high93.9Very high105 Ų10552.3 Ų52.349%0.49128%0.276SS..SBendtrans-75.1-27.4-180-55.484.4178.100113.3K362 S409 P413K362-E411 IonicContact NZ-OE1 2.8Å; K362-E411 PolarHBondContact NZ-OE1 3.16Å; S409-E411 VanDerWaalsContact C-N 3.26Å; S409-E411 WeakPolarHBondContact CB-OE2 3.32Å; S409-E411 PolarHBondContact O-N 3.04Å; S409-E411 PolarHBondContact OG-N 3.26Å; S409-E411 PolarHBondContact OG-OE2 3.25Å; E411-P413 VanDerWaalsContact C-CD 3.45Å
412Q96.2Very high93.8Very high161 Ų16151.4 Ų51.475%0.75227%0.269SS*.SBendtrans-127.360.7178.7-64-175.76.200111.4A408 S409A408-Q412 WeakPolarHBondContact CB-O 3.31Å; S409-Q412 CarbonylContact O-C 3.44Å; S409-Q412 VanDerWaalsContact O-C 3.31Å; S409-Q412 PolarHBondContact O-N 3.12Å; S409-Q412 PolarHBondContact OG-N 3.39Å
413P96.2Very high93.8Very high18 Ų1845.1 Ų45.112%0.11724%0.237CC..  trans-73.1163.5-175.933.3-34.5000111.3P331 F410 E411 S415P331-P413 HydrophobicContact CB-CB 3.45Å; P331-P413 VanDerWaalsContact CB-CB 3.45Å; P331-P413 HydrophobicContact CB-CG 3.78Å; P331-P413 HydrophobicContact CG-CB 4.24Å; F410-P413 WeakPolarHBondContact O-CD 3.47Å; E411-P413 VanDerWaalsContact C-CD 3.45Å; P413-S415 PolarHBondContact O-N 3.43Å
414F93.7Very high93.8Very high41 Ų4145.3 Ų45.318%0.1824%0.241CC..SBendtrans-68.3-28.2174.2-61.7-58.9000112.9L332 M333 R335 S404 N405 A408L332-F414 HydrophobicContact CD2-CB 4.3Å; L332-F414 HydrophobicContact CG-CB 4.38Å; L332-F414 WeakPolarHBondContact O-CB 3.36Å; L332-F414 PolarHBondContact O-N 3.17Å; M333-F414 VanDerWaalsContact O-CE2 3.31Å; M333-F414 WeakPolarHBondContact O-CE2 3.44Å; R335-F414 HydrophobicContact CB-CD2 4.1Å; R335-F414 HydrophobicContact CB-CE2 3.75Å; R335-F414 HydrophobicContact CB-CZ 3.99Å; R335-F414 VanDerWaalsContact CD-CD1 3.46Å; R335-F414 HydrophobicContact CG-CB 4.33Å; R335-F414 HydrophobicContact CG-CD1 4.04Å; R335-F414 HydrophobicContact CG-CD2 3.54Å; R335-F414 HydrophobicContact CG-CE1 4.2Å; R335-F414 HydrophobicContact CG-CE2 3.71Å; R335-F414 HydrophobicContact CG-CG 3.7Å; R335-F414 HydrophobicContact CG-CZ 4.05Å; R335-F414 VanDerWaalsContact CZ-CD1 3.45Å; R335-F414 VanDerWaalsContact NE-CD1 3.32Å; S404-F414 WeakPolarHBondContact O-CE1 3.5Å; S404-F414 VanDerWaalsContact O-CZ 3.23Å; S404-F414 WeakPolarHBondContact O-CZ 3.26Å; N405-F414 VanDerWaalsContact C-CZ 3.46Å; N405-F414 VanDerWaalsContact O-CZ 3.31Å; N405-F414 WeakPolarHBondContact O-CZ 3.41Å; A408-F414 HydrophobicContact CB-CD1 4.38Å; A408-F414 HydrophobicContact CB-CD2 3.88Å; A408-F414 HydrophobicContact CB-CE1 4.19Å; A408-F414 HydrophobicContact CB-CE2 3.68Å; A408-F414 HydrophobicContact CB-CG 4.24Å; A408-F414 HydrophobicContact CB-CZ 3.84Å
415S92.1Very high93.9Very high47 Ų4743.1 Ų43.133%0.32923%0.231SC..BIsolated β-bridgetrans-154143171.41760000108.4P331 L332 P413 H417P331-S415 CarbonylContact C-O 3.57Å; P331-S415 VanDerWaalsContact CA-O 3.27Å; P331-S415 WeakPolarHBondContact CA-O 3.45Å; P331-S415 VanDerWaalsContact CB-O 3.26Å; P331-S415 WeakPolarHBondContact CB-O 3.37Å; L332-S415 PolarHBondContact N-O 2.82Å; P413-S415 PolarHBondContact O-N 3.43Å; S415-H417 PolarHBondContact O-N 3.17Å; S415-H417 PolarHBondContact OG-N 2.81Å; S415-H417 VanDerWaalsContact OG-N 3.16Å; S415-H417 PolarHBondContact OG-O 2.89Å
416H92.5Very high94Very high142 Ų14241.1 Ų41.166%0.65722%0.221SC*.SBendtrans-74.1-3173.1-67-72000113.4
417H90Very high94.1Very high32 Ų3241 Ų4115%0.14822%0.22CC..SBendtrans-120.3141.8176.3179.6-88.6000110.5S327 D328 V330 S415 G419 T420S327-H417 VanDerWaalsContact O-CA 3.32Å; S327-H417 WeakPolarHBondContact O-CA 3.43Å; S327-H417 PolarHBondContact O-CD2 3.05Å; S327-H417 VanDerWaalsContact O-CD2 3.23Å; S327-H417 PolarHBondContact OG-CD2 2.79Å; S327-H417 PolarHBondContact OG-CE1 2.66Å; S327-H417 PolarHBondContact OG-ND1 2.91Å; S327-H417 PolarHBondContact OG-NE2 2.95Å; D328-H417 IonicContact OD1-CD2 2.82Å; D328-H417 PolarHBondContact OD1-CD2 3.05Å; D328-H417 IonicContact OD1-NE2 2.66Å; V330-H417 CarbonylContact O-C 3.52Å; S415-H417 PolarHBondContact O-N 3.17Å; S415-H417 PolarHBondContact OG-N 2.81Å; S415-H417 VanDerWaalsContact OG-N 3.16Å; S415-H417 PolarHBondContact OG-O 2.89Å; H417-G419 PolarHBondContact ND1-N 3.16Å; H417-G419 PolarHBondContact O-N 2.71Å; H417-T420 PolarHBondContact CE1-O 3.43Å
418G85.9Confident94.1Very high0 Ų041.8 Ų41.80%023%0.228CC..  trans-68.710.1-17200000116.2L295 S327 V330 T420L295-G418 CarbonylContact O-C 3.51Å; S327-G418 PolarHBondContact O-N 2.89Å; S327-G418 PolarHBondContact OG-N 3.09Å; V330-G418 WeakPolarHBondContact O-CA 3.45Å; V330-G418 PolarHBondContact O-N 3.18Å; G418-T420 VanDerWaalsContact C-N 3.27Å; G418-T420 PolarHBondContact O-N 3.09Å
419G84.2Confident94.2Very high2 Ų244.4 Ų44.42%0.02124%0.237CC..SBendtrans74.18171.100000116.4H417 K433 T434 S435H417-G419 PolarHBondContact ND1-N 3.16Å; H417-G419 PolarHBondContact O-N 2.71Å; G419-K433 CarbonylContact O-C 3.48Å; G419-K433 WeakPolarHBondContact O-CA 3.37Å; G419-T434 PolarHBondContact O-N 2.82Å; G419-T434 PolarHBondContact O-OG1 3.45Å; G419-S435 PolarHBondContact O-N 2.8Å; G419-S435 VanDerWaalsContact O-N 3.14Å; G419-S435 PolarHBondContact O-OG 3.48Å
420T88.8Confident94.3Very high4 Ų442.6 Ų42.63%0.02522%0.224CC..EExtended strand (participates in β ladder)trans-126.3123.1173.2-58.10000108.9T304 S327 H417 G418 M432T304-T420 HydrophobicContact CG2-CG2 4.39Å; S327-T420 WeakPolarHBondContact CB-O 3.38Å; S327-T420 PolarHBondContact OG-O 3Å; H417-T420 PolarHBondContact CE1-O 3.43Å; G418-T420 VanDerWaalsContact C-N 3.27Å; G418-T420 PolarHBondContact O-N 3.09Å; T420-M432 WeakPolarHBondContact CA-O 3.29Å
421K91.4Very high94.4Very high31 Ų3139.4 Ų39.414%0.13521%0.21CC..EExtended strand (participates in β ladder)trans-114.2138.1177.4-158.669.9175.2175.40109.9D328 L423 V431 M432 T434D328-K421 IonicContact OD1-NZ 2.66Å; D328-K421 PolarHBondContact OD1-NZ 3.4Å; D328-K421 VanDerWaalsContact OD1-NZ 3.17Å; K421-L423 HydrophobicContact CG-CD2 4.49Å; K421-V431 WeakPolarHBondContact O-CA 3.32Å; K421-M432 PolarHBondContact N-O 2.99Å; K421-M432 PolarHBondContact O-N 3.32Å; K421-T434 HydrophobicContact CB-CG2 3.89Å
422V95.5Very high94.3Very high12 Ų1234.4 Ų34.47%0.07319%0.187CC..EExtended strand (participates in β ladder)trans-83.3130.4166.7-179.70000107.5W320 A430 G551W320-V422 HydrophobicContact CB-CG1 4.1Å; W320-V422 HydrophobicContact CB-CG2 3.69Å; W320-V422 HydrophobicContact CE3-CG1 4.34Å; W320-V422 HydrophobicContact CG-CG2 4.41Å; W320-V422 WeakPolarHBondContact O-CG2 3.49Å; V422-A430 WeakPolarHBondContact CA-O 3.45Å; V422-G551 WeakPolarHBondContact O-CA 3.4Å
423L97.7Very high94.1Very high0 Ų027.5 Ų27.50%016%0.155CC..EExtended strand (participates in β ladder)trans-102.2145.2173.8-48.8179.5000109.5K421 R429 A430 M432 A522 V546 G551 L553K421-L423 HydrophobicContact CG-CD2 4.49Å; L423-R429 WeakPolarHBondContact O-CA 3.15Å; L423-A430 HydrophobicContact CB-CB 4.29Å; L423-A430 PolarHBondContact N-O 3.26Å; L423-A430 PolarHBondContact O-N 3.32Å; L423-M432 HydrophobicContact CD1-CB 3.89Å; L423-M432 HydrophobicContact CD1-SD 4.39Å; L423-M432 HydrophobicContact CD2-CB 4.26Å; L423-M432 HydrophobicContact CG-CB 4.07Å; L423-A522 HydrophobicContact CD1-CB 3.49Å; L423-A522 VanDerWaalsContact CD1-CB 3.49Å; L423-V546 HydrophobicContact CD1-CG1 4.09Å; L423-G551 CarbonylContact C-O 3.49Å; L423-G551 VanDerWaalsContact CA-O 3.25Å; L423-G551 WeakPolarHBondContact CA-O 3.39Å; L423-L553 HydrophobicContact CB-CB 3.87Å; L423-L553 HydrophobicContact CD1-CB 4.47Å
424S98Very high93.8Very high45 Ų4527.2 Ų27.232%0.31515%0.153SC..EExtended strand (participates in β ladder)trans-146.8144.5178.7-67.50000110.7G428 R429 G551 E552 L553S424-G428 WeakPolarHBondContact CA-O 3.39Å; S424-R429 PolarHBondContact OG-NH1 2.93Å; S424-G551 PolarHBondContact N-O 3.3Å; S424-E552 WeakPolarHBondContact O-CA 3.43Å; S424-L553 PolarHBondContact O-N 2.93Å
425G98.1Very high93.4Very high38 Ų3826.6 Ų26.639%0.39215%0.153SC..EExtended strand (participates in β ladder)trans171.9-161174.800000110.4L427 G428 L553G425-L427 PolarHBondContact O-N 3.02Å; G425-G428 PolarHBondContact N-O 3.16Å; G425-G428 VanDerWaalsContact N-O 3.09Å; G425-G428 PolarHBondContact O-N 2.9Å; G425-L553 CarbonylContact C-O 3.05Å; G425-L553 WeakPolarHBondContact CA-O 3.41Å
426N98.1Very high93.1Very high71 Ų7125.3 Ų25.338%0.3815%0.145SC..THydrogen-bonded Turntrans-65.8-23.9-176.767.1-10.7000113.2G428 L534 T554 L555N426-G428 PolarHBondContact O-N 2.78Å; N426-L534 HydrophobicContact CB-CD2 4.01Å; N426-L534 WeakPolarHBondContact O-CD2 3.34Å; N426-T554 VanDerWaalsContact OD1-CA 3.32Å; N426-T554 WeakPolarHBondContact OD1-CA 3.35Å; N426-L555 PolarHBondContact ND2-O 3Å; N426-L555 PolarHBondContact OD1-N 3.3Å
427L98.4Very high93Very high2 Ų218.9 Ų18.91%0.0112%0.116CC..THydrogen-bonded Turntrans-71.7-9.7173.6-78.3171.5000113.6G425 L534 L535 V538 I544 L553 L555G425-L427 PolarHBondContact O-N 3.02Å; L427-L534 HydrophobicContact CD2-CB 4.31Å; L427-L534 HydrophobicContact CD2-CD2 4.29Å; L427-L534 HydrophobicContact CD2-CG 4.28Å; L427-L535 HydrophobicContact CD2-CD1 4.44Å; L427-V538 HydrophobicContact CD2-CG2 3.91Å; L427-I544 HydrophobicContact CD1-CG2 4.06Å; L427-L553 HydrophobicContact CB-CD2 4.08Å; L427-L553 HydrophobicContact CB-CG 3.97Å; L427-L553 HydrophobicContact CD1-CD1 4.08Å; L427-L553 HydrophobicContact CD1-CG 3.96Å; L427-L555 HydrophobicContact CD1-CB 4.1Å; L427-L555 HydrophobicContact CD2-CB 3.99Å; L427-L555 HydrophobicContact CD2-CD2 4.32Å; L427-L555 HydrophobicContact CG-CB 3.82Å
428G98Very high92.9Very high16 Ų1619.6 Ų19.617%0.16512%0.123CC..EExtended strand (participates in β ladder)trans112.1-145.4-178.800000112S424 G425 N426S424-G428 WeakPolarHBondContact CA-O 3.39Å; G425-G428 PolarHBondContact N-O 3.16Å; G425-G428 VanDerWaalsContact N-O 3.09Å; G425-G428 PolarHBondContact O-N 2.9Å; N426-G428 PolarHBondContact O-N 2.78Å
429R98.4Very high93.1Very high59 Ų5924 Ų2422%0.22315%0.15CC..EExtended strand (participates in β ladder)trans-117145177.6-67.1175.559.490.7-16.7110.4W320 D321 L423 S424 V525 T526 E595W320-R429 HydrophobicContact CE3-CB 4.03Å; W320-R429 HydrophobicContact CZ3-CB 3.78Å; D321-R429 IonicContact OD1-CZ 2.85Å; D321-R429 IonicContact OD1-NH1 2.79Å; D321-R429 PolarHBondContact OD1-NH1 3.3Å; D321-R429 IonicContact OD1-NH2 3.12Å; D321-R429 PolarHBondContact OD1-NH2 2.87Å; D321-R429 IonicContact OD2-NH2 3.71Å; L423-R429 WeakPolarHBondContact O-CA 3.15Å; S424-R429 PolarHBondContact OG-NH1 2.93Å; R429-V525 CarbonylContact O-C 3.55Å; R429-V525 WeakPolarHBondContact O-CA 3.29Å; R429-T526 PolarHBondContact N-O 2.87Å; R429-T526 PolarHBondContact O-N 2.86Å; R429-E595 WeakPolarHBondContact CD-OE2 3.41Å; R429-E595 IonicContact CZ-OE1 3.91Å; R429-E595 IonicContact CZ-OE2 2.82Å; R429-E595 IonicContact NE-OE1 3.16Å; R429-E595 PolarHBondContact NE-OE1 3.22Å; R429-E595 VanDerWaalsContact NE-OE1 3.13Å; R429-E595 IonicContact NE-OE2 3.71Å; R429-E595 PolarHBondContact NE-OE2 3.35Å; R429-E595 IonicContact NH2-OE1 3.47Å; R429-E595 PolarHBondContact NH2-OE1 3.44Å
430A98Very high93.4Very high0 Ų030 Ų300%018%0.178CC..EExtended strand (participates in β ladder)trans-149.1174.8179.300000110.8V422 L423 A522 I523 V525 L553V422-A430 WeakPolarHBondContact CA-O 3.45Å; L423-A430 HydrophobicContact CB-CB 4.29Å; L423-A430 PolarHBondContact N-O 3.26Å; L423-A430 PolarHBondContact O-N 3.32Å; A430-A522 HydrophobicContact CB-CB 4.3Å; A430-I523 WeakPolarHBondContact CB-O 3.33Å; A430-V525 HydrophobicContact CB-CG2 3.89Å; A430-L553 HydrophobicContact CB-CD2 3.85Å
431V96Very high93.5Very high1 Ų131 Ų311%0.00618%0.183CC..EExtended strand (participates in β ladder)trans-122.8146170.1-61.60000110.5T301 T304 W320 K421 I523 H524T301-V431 HydrophobicContact CG2-CG2 4.42Å; T304-V431 HydrophobicContact CG2-CG1 4.29Å; W320-V431 HydrophobicContact CD2-CG1 3.72Å; W320-V431 HydrophobicContact CE3-CG1 4.1Å; W320-V431 HydrophobicContact CG-CG1 4.19Å; W320-V431 HydrophobicContact CH2-CG1 4.24Å; W320-V431 HydrophobicContact CZ2-CG1 3.86Å; W320-V431 HydrophobicContact CZ3-CG1 4.35Å; K421-V431 WeakPolarHBondContact O-CA 3.32Å; V431-I523 HydrophobicContact CG2-CD1 4.31Å; V431-I523 HydrophobicContact CG2-CG1 3.79Å; V431-I523 PolarHBondContact N-O 3Å; V431-I523 WeakPolarHBondContact O-CG1 3.46Å; V431-I523 PolarHBondContact O-N 2.84Å; V431-H524 HydrophobicContact CG2-CB 4.26Å; V431-H524 WeakPolarHBondContact CG2-ND1 3.43Å
432M93.8Very high93.7Very high0 Ų030.9 Ų30.90%018%0.183CC..EExtended strand (participates in β ladder)trans-133.3131.5176.1175.2175.5168.700109.9T420 K421 L423 T434 V437 P520 S521 V546T420-M432 WeakPolarHBondContact CA-O 3.29Å; K421-M432 PolarHBondContact N-O 2.99Å; K421-M432 PolarHBondContact O-N 3.32Å; L423-M432 HydrophobicContact CD1-CB 3.89Å; L423-M432 HydrophobicContact CD1-SD 4.39Å; L423-M432 HydrophobicContact CD2-CB 4.26Å; L423-M432 HydrophobicContact CG-CB 4.07Å; M432-T434 HydrophobicContact CE-CG2 4.24Å; M432-T434 HydrophobicContact CG-CG2 4.19Å; M432-T434 PolarHBondContact O-N 3Å; M432-T434 HydrophobicContact SD-CG2 4.42Å; M432-V437 HydrophobicContact CE-CB 4.35Å; M432-V437 HydrophobicContact CE-CG1 4.18Å; M432-V437 HydrophobicContact CE-CG2 4.12Å; M432-P520 HydrophobicContact CE-CB 3.45Å; M432-P520 VanDerWaalsContact CE-CB 3.45Å; M432-P520 HydrophobicContact SD-CB 4.45Å; M432-S521 WeakPolarHBondContact CA-O 3.39Å; M432-S521 WeakPolarHBondContact CB-O 3.45Å; M432-S521 WeakPolarHBondContact CG-O 3.48Å; M432-V546 HydrophobicContact SD-CG1 4.28Å
433K91Very high93.8Very high17 Ų1733 Ų337%0.07420%0.196CC..EExtended strand (participates in β ladder)trans-81.9102.6171.2-163.6-178-168.2-171.70109.1G298 T301 N339 G419 V437 G514G298-K433 WeakPolarHBondContact O-CE 3.48Å; G298-K433 PolarHBondContact O-NZ 3.49Å; T301-K433 HydrophobicContact CG2-CB 3.91Å; N339-K433 VanDerWaalsContact OD1-CE 3.24Å; N339-K433 WeakPolarHBondContact OD1-CE 3.48Å; N339-K433 PolarHBondContact OD1-NZ 3.42Å; G419-K433 CarbonylContact O-C 3.48Å; G419-K433 WeakPolarHBondContact O-CA 3.37Å; K433-V437 WeakPolarHBondContact O-CG2 3.19Å; K433-G514 PolarHBondContact NZ-O 2.91Å
434T89.8Confident93.8Very high12 Ų1233.2 Ų33.27%0.07420%0.197CC..  trans-85.4-21.2-179.555.50000113G419 K421 M432 A436 V437 Q442G419-T434 PolarHBondContact O-N 2.82Å; G419-T434 PolarHBondContact O-OG1 3.45Å; K421-T434 HydrophobicContact CB-CG2 3.89Å; M432-T434 HydrophobicContact CE-CG2 4.24Å; M432-T434 HydrophobicContact CG-CG2 4.19Å; M432-T434 PolarHBondContact O-N 3Å; M432-T434 HydrophobicContact SD-CG2 4.42Å; T434-A436 VanDerWaalsContact C-N 3.27Å; T434-A436 PolarHBondContact O-N 3.01Å; T434-V437 PolarHBondContact O-N 3.42Å; T434-V437 VanDerWaalsContact O-N 3.15Å; T434-Q442 PolarHBondContact O-NE2 3.22Å
435S86.6Confident93.8Very high28 Ų2836 Ų3620%0.19621%0.205CC..THydrogen-bonded Turntrans-63.5-28-177.943.40000114.9G419G419-S435 PolarHBondContact O-N 2.8Å; G419-S435 VanDerWaalsContact O-N 3.14Å; G419-S435 PolarHBondContact O-OG 3.48Å
436A85.1Confident93.8Very high19 Ų1934.4 Ų34.416%0.15719%0.188CC..THydrogen-bonded Turntrans-94.4-5.9179.100000113.2T434 K518T434-A436 VanDerWaalsContact C-N 3.27Å; T434-A436 PolarHBondContact O-N 3.01Å; A436-K518 VanDerWaalsContact O-CA 3.29Å; A436-K518 WeakPolarHBondContact O-CA 3.33Å
437V89.1Confident93.8Very high8 Ų833.2 Ų33.25%0.04818%0.184CC..SBendtrans-104.4121.6-172.3-178.70000109.8M432 K433 T434 N441 Q442 P520M432-V437 HydrophobicContact CE-CB 4.35Å; M432-V437 HydrophobicContact CE-CG1 4.18Å; M432-V437 HydrophobicContact CE-CG2 4.12Å; K433-V437 WeakPolarHBondContact O-CG2 3.19Å; T434-V437 PolarHBondContact O-N 3.42Å; T434-V437 VanDerWaalsContact O-N 3.15Å; V437-N441 HydrophobicContact CG1-CB 4.17Å; V437-Q442 HydrophobicContact CB-CG 4.17Å; V437-Q442 HydrophobicContact CG1-CG 3.79Å; V437-Q442 PolarHBondContact O-NE2 2.89Å; V437-P520 HydrophobicContact CG1-CB 4.05Å
438P88.4Confident93.9Very high46 Ų4633.1 Ų33.130%0.29918%0.184SC..  trans-54.5141.6174.2-24.233.6000111.9E440 N441 Q442P438-E440 VanDerWaalsContact CB-CD 3.44Å; P438-E440 HydrophobicContact CB-CG 4.35Å; P438-E440 WeakPolarHBondContact CB-OE1 3.26Å; P438-E440 WeakPolarHBondContact CB-OE2 3.27Å; P438-E440 PolarHBondContact O-N 2.94Å; P438-E440 VanDerWaalsContact O-N 3.17Å; P438-N441 CarbonylContact O-C 3.55Å; P438-N441 WeakPolarHBondContact O-CA 3.17Å; P438-N441 PolarHBondContact O-N 2.97Å; P438-Q442 PolarHBondContact O-N 3.49Å
439V89.8Confident93.9Very high93 Ų9333 Ų3356%0.56418%0.18SC*.G310 helixtrans-55.5-39-171.8175.80000112N441 Q442 Q549V439-N441 PolarHBondContact O-N 3.22Å; V439-Q442 PolarHBondContact O-N 2.79Å; V439-Q549 PolarHBondContact O-NE2 3.44Å
440E90.5Very high93.9Very high129 Ų12931.1 Ų31.160%0.60318%0.175SC*.G310 helixtrans-67.3-11.9178.266.8-87.9-156.500114.9P438 K503P438-E440 VanDerWaalsContact CB-CD 3.44Å; P438-E440 HydrophobicContact CB-CG 4.35Å; P438-E440 WeakPolarHBondContact CB-OE1 3.26Å; P438-E440 WeakPolarHBondContact CB-OE2 3.27Å; P438-E440 PolarHBondContact O-N 2.94Å; P438-E440 VanDerWaalsContact O-N 3.17Å; E440-K503 PolarHBondContact O-NZ 3.17Å
441N92.7Very high93.9Very high24 Ų2432.1 Ų32.113%0.12818%0.179CC..G310 helixtrans-114.85.1177.6-66.7-18.4000112V437 P438 V439 V443 K503 P520V437-N441 HydrophobicContact CG1-CB 4.17Å; P438-N441 CarbonylContact O-C 3.55Å; P438-N441 WeakPolarHBondContact O-CA 3.17Å; P438-N441 PolarHBondContact O-N 2.97Å; V439-N441 PolarHBondContact O-N 3.22Å; N441-V443 VanDerWaalsContact C-N 3.26Å; N441-V443 PolarHBondContact O-N 2.86Å; N441-K503 PolarHBondContact OD1-NZ 2.98Å; N441-P520 WeakPolarHBondContact O-CB 3.15Å; N441-P520 VanDerWaalsContact O-CG 3.25Å; N441-P520 WeakPolarHBondContact O-CG 3.15Å
442Q94.4Very high93.8Very high28 Ų2834.8 Ų34.813%0.13119%0.192CC..SBendtrans-77.7-11.7177.5-69.6178.9700113.3T434 V437 P438 V439 G548 Q549T434-Q442 PolarHBondContact O-NE2 3.22Å; V437-Q442 HydrophobicContact CB-CG 4.17Å; V437-Q442 HydrophobicContact CG1-CG 3.79Å; V437-Q442 PolarHBondContact O-NE2 2.89Å; P438-Q442 PolarHBondContact O-N 3.49Å; V439-Q442 PolarHBondContact O-N 2.79Å; Q442-G548 PolarHBondContact O-N 3.19Å; Q442-Q549 HydrophobicContact CB-CG 4.02Å
443V97.1Very high93.8Very high58 Ų5836.6 Ų36.635%0.35220%0.204SC..EExtended strand (participates in β ladder)trans-124.1115.8175.4-171.30000108.6N441 V546 N547 Q549N441-V443 VanDerWaalsContact C-N 3.26Å; N441-V443 PolarHBondContact O-N 2.86Å; V443-V546 WeakPolarHBondContact CA-O 3.41Å; V443-N547 HydrophobicContact CG1-CB 4.37Å; V443-N547 WeakPolarHBondContact CG2-OD1 3.2Å; V443-Q549 HydrophobicContact CG2-CB 4.37Å; V443-Q549 HydrophobicContact CG2-CG 3.87Å
444I97.8Very high93.9Very high4 Ų436.4 Ų36.42%0.02120%0.203CC..EExtended strand (participates in β ladder)trans-127.9126.9177.8-56.2-66.3000107.7A446 V471 K503 A505 P520 R545 V546I444-A446 HydrophobicContact CG2-CB 4.18Å; I444-V471 HydrophobicContact CG2-CG2 4.23Å; I444-K503 HydrophobicContact CD1-CB 3.86Å; I444-K503 HydrophobicContact CD1-CD 3.86Å; I444-K503 HydrophobicContact CD1-CG 4.41Å; I444-A505 HydrophobicContact CB-CB 3.88Å; I444-A505 HydrophobicContact CG1-CB 4.05Å; I444-A505 HydrophobicContact CG2-CB 3.88Å; I444-P520 HydrophobicContact CD1-CG 4.49Å; I444-P520 HydrophobicContact CG1-CG 3.76Å; I444-R545 CarbonylContact O-C 3.59Å; I444-R545 WeakPolarHBondContact O-CA 3.48Å; I444-V546 PolarHBondContact N-O 2.82Å; I444-V546 PolarHBondContact O-N 3.06Å
445E98.4Very high94.1Very high103 Ų10339.5 Ų39.548%0.48122%0.217SC..EExtended strand (participates in β ladder)trans-127.1109.3169.1-176.3176.3122.600107.3I543 I544 R545E445-I543 HydrophobicContact CG-CG2 3.51Å; E445-I544 VanDerWaalsContact CA-O 3.32Å; E445-I544 WeakPolarHBondContact CA-O 3.32Å; E445-R545 HydrophobicContact CB-CB 4.48Å; E445-R545 HydrophobicContact CG-CB 4.33Å; E445-R545 IonicContact OE2-CZ 3.83Å; E445-R545 IonicContact OE2-NE 2.81Å; E445-R545 PolarHBondContact OE2-NE 3.41Å; E445-R545 IonicContact OE2-NH2 3.37Å; E445-R545 PolarHBondContact OE2-NH2 3.5Å
446A98.6Very high94.5Very high4 Ų441.7 Ų41.73%0.03323%0.226CC..EExtended strand (participates in β ladder)trans-154.5163.6-172.800000111.7I444 D469 V471 I544I444-A446 HydrophobicContact CG2-CB 4.18Å; A446-D469 HydrophobicContact CB-CB 4.38Å; A446-V471 HydrophobicContact CB-CG2 4.12Å; A446-I544 PolarHBondContact N-O 3.4Å; A446-I544 VanDerWaalsContact N-O 3.15Å; A446-I544 PolarHBondContact O-N 3.35Å
447P98.7Very high95Very high47 Ų4740.8 Ų40.831%0.30522%0.219SC..EExtended strand (participates in β ladder)trans-63.6140.7175.9-19.231.7000112.3C470 V471 D542 I543P447-C470 CarbonylContact O-C 3.59Å; P447-C470 VanDerWaalsContact O-CA 3.28Å; P447-C470 WeakPolarHBondContact O-CA 3.49Å; P447-C470 WeakPolarHBondContact O-CB 3.46Å; P447-V471 PolarHBondContact O-N 2.89Å; P447-D542 CarbonylContact C-O 3.58Å; P447-D542 WeakPolarHBondContact CA-O 3.17Å; P447-I543 HydrophobicContact CB-CD1 4.23Å; P447-I543 HydrophobicContact CG-CD1 3.85Å
448A98.8Very high95.2Very high0 Ų042.6 Ų42.60%023%0.228CC..EExtended strand (participates in β ladder)trans-70.7140.4176.100000111V450 V471 V473 V538 D540 G541 D542 I544A448-V450 HydrophobicContact CB-CG2 4.32Å; A448-V471 CarbonylContact C-O 3.43Å; A448-V471 VanDerWaalsContact CA-O 3.29Å; A448-V471 WeakPolarHBondContact CA-O 3.16Å; A448-V473 HydrophobicContact CB-CG2 4.09Å; A448-V538 HydrophobicContact CB-CG1 3.84Å; A448-D540 WeakPolarHBondContact O-CA 3.41Å; A448-G541 PolarHBondContact O-N 3.44Å; A448-D542 HydrophobicContact CB-CB 4.36Å; A448-D542 WeakPolarHBondContact CB-O 3.19Å; A448-D542 PolarHBondContact N-O 3.37Å; A448-I544 HydrophobicContact CB-CD1 3.81Å; A448-I544 HydrophobicContact CB-CG1 4.34Å
449V98.6Very high95.6Very high13 Ų1343.9 Ų43.98%0.07924%0.236CC..EExtended strand (participates in β ladder)trans-121.5111.2162.3-174.20000107.2F451 L466 C470 V471 V473 D540V449-F451 HydrophobicContact CB-CE2 4.16Å; V449-F451 HydrophobicContact CG1-CD2 4.45Å; V449-F451 HydrophobicContact CG1-CE2 3.54Å; V449-F451 HydrophobicContact CG1-CZ 3.65Å; V449-L466 HydrophobicContact CB-CD2 4.16Å; V449-L466 HydrophobicContact CG1-CD2 3.84Å; V449-L466 HydrophobicContact CG2-CD2 4.22Å; V449-C470 HydrophobicContact CG2-CB 3.88Å; V449-V471 PolarHBondContact N-O 3.02Å; V449-V473 PolarHBondContact O-N 3.27Å; V449-D540 WeakPolarHBondContact CA-OD1 3.48Å
450V98.4Very high95.9Very high20 Ų2039.9 Ų39.912%0.12121%0.213CC..EExtended strand (participates in β ladder)trans-96.7132.7-166.8-174.20000110.9A448 V473 R475 V538 D540A448-V450 HydrophobicContact CB-CG2 4.32Å; V450-V473 CarbonylContact C-O 3.59Å; V450-V473 HydrophobicContact CG2-CB 4.3Å; V450-R475 HydrophobicContact CG1-CG 4.48Å; V450-V538 HydrophobicContact CG2-CB 4.49Å; V450-V538 HydrophobicContact CG2-CG1 3.8Å; V450-D540 PolarHBondContact N-OD1 3.49Å
451F97.7Very high96.2Very high21 Ų2134.3 Ų34.39%0.09219%0.186CC..EExtended strand (participates in β ladder)trans-129.9149.2176.2-60-82.8000110.5V449 D456 V457 A460 L466 V472 V473 V474 R475V449-F451 HydrophobicContact CB-CE2 4.16Å; V449-F451 HydrophobicContact CG1-CD2 4.45Å; V449-F451 HydrophobicContact CG1-CE2 3.54Å; V449-F451 HydrophobicContact CG1-CZ 3.65Å; F451-D456 HydrophobicContact CD1-CB 3.57Å; F451-D456 HydrophobicContact CE1-CB 4.24Å; F451-D456 HydrophobicContact CG-CB 4.45Å; F451-V457 HydrophobicContact CB-CG2 4.27Å; F451-V457 HydrophobicContact CD1-CG2 4.11Å; F451-V457 HydrophobicContact CD2-CG2 3.7Å; F451-V457 HydrophobicContact CE1-CG2 4.35Å; F451-V457 HydrophobicContact CE2-CG2 3.97Å; F451-V457 HydrophobicContact CG-CG2 3.76Å; F451-V457 HydrophobicContact CZ-CG2 4.27Å; F451-A460 HydrophobicContact CE1-CB 3.7Å; F451-A460 HydrophobicContact CZ-CB 3.68Å; F451-L466 HydrophobicContact CE2-CD2 4.25Å; F451-L466 HydrophobicContact CZ-CD2 4.1Å; F451-V472 HydrophobicContact CD2-CG1 3.84Å; F451-V472 HydrophobicContact CE2-CG1 3.89Å; F451-V473 PolarHBondContact N-O 3.48Å; F451-V474 HydrophobicContact CB-CG2 4.35Å; F451-V474 WeakPolarHBondContact O-CA 3.3Å; F451-R475 PolarHBondContact O-N 2.87Å; F451-R475 VanDerWaalsContact O-N 3.17Å
452E93.8Very high96.4Very high57 Ų5739.8 Ų39.827%0.26621%0.211SC..SBendtrans-97-16.3174.2-56.2-56.6150.200112R475 H476 Q477 H568E452-R475 IonicContact OE1-CZ 3.39Å; E452-R475 IonicContact OE1-NE 3.57Å; E452-R475 PolarHBondContact OE1-NE 3.36Å; E452-R475 IonicContact OE1-NH2 3.17Å; E452-R475 PolarHBondContact OE1-NH2 3.22Å; E452-R475 WeakPolarHBondContact OE2-CG 3.42Å; E452-R475 IonicContact OE2-NE 2.76Å; E452-R475 PolarHBondContact OE2-NE 3.16Å; E452-H476 IonicContact OE2-CE1 3.25Å; E452-H476 IonicContact OE2-CG 3.51Å; E452-H476 IonicContact OE2-ND1 3.51Å; E452-H476 PolarHBondContact OE2-ND1 2.63Å; E452-Q477 PolarHBondContact O-NE2 2.88Å; E452-H568 IonicContact OE1-CD2 3.71Å; E452-H568 PolarHBondContact OE1-CD2 2.94Å; E452-H568 VanDerWaalsContact OE1-CD2 3.25Å; E452-H568 IonicContact OE1-NE2 3.56Å; E452-H568 IonicContact OE2-CD2 2.68Å
453S93.4Very high96.5Very high37 Ų3741.9 Ų41.926%0.25923%0.233SC..SBendtrans-143149.2178.31790000112.4H455 D456S453-H455 PolarHBondContact O-N 3.47Å; S453-H455 VanDerWaalsContact O-N 3.14Å; S453-H455 PolarHBondContact OG-N 2.74Å; S453-H455 VanDerWaalsContact OG-N 3.16Å; S453-D456 WeakPolarHBondContact CB-OD2 3.26Å; S453-D456 PolarHBondContact N-OD2 3.28Å; S453-D456 VanDerWaalsContact N-OD2 3.17Å; S453-D456 PolarHBondContact O-N 3.03Å
454Q94.1Very high96.4Very high13 Ų1340.5 Ų40.56%0.06123%0.231CC..Hα-helixtrans-62.6-17.8170.773.6-179.8-68.700112.9D456 L487 K489 L490Q454-D456 VanDerWaalsContact C-N 3.29Å; Q454-L487 HydrophobicContact CB-CB 4.29Å; Q454-L487 HydrophobicContact CB-CD2 4.22Å; Q454-L487 HydrophobicContact CG-CD2 4.47Å; Q454-K489 HydrophobicContact CG-CB 4.49Å; Q454-L490 HydrophobicContact CB-CD2 3.79Å; Q454-L490 HydrophobicContact CB-CG 4.07Å
455H93.6Very high96.4Very high77 Ų7745.5 Ų45.536%0.35626%0.257SS..Hα-helixtrans-76.7-17.9179.4-65.82.6000112.8S453 P459 K489S453-H455 PolarHBondContact O-N 3.47Å; S453-H455 VanDerWaalsContact O-N 3.14Å; S453-H455 PolarHBondContact OG-N 2.74Å; S453-H455 VanDerWaalsContact OG-N 3.16Å; H455-P459 WeakPolarHBondContact O-CD 3.4Å; H455-K489 PolarHBondContact CE1-NZ 3.38Å
456D94.5Very high96.3Very high74 Ų7440.6 Ų40.640%0.39623%0.234SC..Hα-helixtrans-84.4-19.6-178.8-53.5-33.8000112.2F451 S453 Q454 P459 A460F451-D456 HydrophobicContact CD1-CB 3.57Å; F451-D456 HydrophobicContact CE1-CB 4.24Å; F451-D456 HydrophobicContact CG-CB 4.45Å; S453-D456 WeakPolarHBondContact CB-OD2 3.26Å; S453-D456 PolarHBondContact N-OD2 3.28Å; S453-D456 VanDerWaalsContact N-OD2 3.17Å; S453-D456 PolarHBondContact O-N 3.03Å; Q454-D456 VanDerWaalsContact C-N 3.29Å; D456-P459 WeakPolarHBondContact O-CD 3.43Å; D456-A460 PolarHBondContact O-N 2.96Å
457V96.2Very high96.3Very high1 Ų143.5 Ų43.51%0.00625%0.249CC..Hα-helixtrans-72.3-40-175.2178.60000112.3F451 A460 F461 L466 V472 V474 L490 P493F451-V457 HydrophobicContact CB-CG2 4.27Å; F451-V457 HydrophobicContact CD1-CG2 4.11Å; F451-V457 HydrophobicContact CD2-CG2 3.7Å; F451-V457 HydrophobicContact CE1-CG2 4.35Å; F451-V457 HydrophobicContact CE2-CG2 3.97Å; F451-V457 HydrophobicContact CG-CG2 3.76Å; F451-V457 HydrophobicContact CZ-CG2 4.27Å; V457-A460 PolarHBondContact O-N 3.41Å; V457-F461 WeakPolarHBondContact O-CB 3.37Å; V457-F461 PolarHBondContact O-N 3.16Å; V457-L466 HydrophobicContact CG1-CD1 3.99Å; V457-V472 HydrophobicContact CG2-CG1 4.39Å; V457-V474 HydrophobicContact CG2-CG2 4.35Å; V457-L490 HydrophobicContact CB-CD2 3.75Å; V457-L490 HydrophobicContact CG1-CD2 3.99Å; V457-L490 HydrophobicContact CG2-CD2 3.47Å; V457-L490 VanDerWaalsContact CG2-CD2 3.47Å; V457-P493 HydrophobicContact CG1-CG 4.5Å
458M93.5Very high96.2Very high46 Ų4647.6 Ų47.623%0.22726%0.258CS..Hα-helixtrans-66.6-46.7-179.4-169.169.6-16600112.2A198 A460 F461 E462 P493A198-M458 HydrophobicContact CB-CE 4.08Å; A198-M458 WeakPolarHBondContact O-CE 3.42Å; M458-A460 VanDerWaalsContact C-N 3.29Å; M458-A460 PolarHBondContact O-N 3.43Å; M458-F461 HydrophobicContact CE-CD1 3.77Å; M458-F461 HydrophobicContact CE-CE1 4.13Å; M458-F461 WeakPolarHBondContact O-CB 3.48Å; M458-F461 PolarHBondContact O-N 3.41Å; M458-F461 VanDerWaalsContact O-N 3.14Å; M458-F461 HydrophobicContact SD-CD1 3.99Å; M458-E462 HydrophobicContact CE-CG 3.94Å; M458-E462 WeakPolarHBondContact CE-OE1 3.47Å; M458-E462 WeakPolarHBondContact O-CG 3.34Å; M458-E462 PolarHBondContact O-N 2.91Å; M458-P493 HydrophobicContact SD-CB 4.09Å; M458-P493 HydrophobicContact SD-CG 4.17Å
459P96.6Very high96.2Very high72 Ų7251.3 Ų51.347%0.46828%0.278SS..Hα-helixtrans-56.2-40.2171.8-27.235.5000113.6H455 D456 E462 A463H455-P459 WeakPolarHBondContact O-CD 3.4Å; D456-P459 WeakPolarHBondContact O-CD 3.43Å; P459-E462 PolarHBondContact O-N 3.01Å; P459-A463 WeakPolarHBondContact O-CB 3.46Å; P459-A463 PolarHBondContact O-N 3.23Å
460A97.3Very high96.2Very high10 Ų1050.7 Ų50.78%0.08328%0.275CS..Hα-helixtrans-67.1-37.7176.900000112.6F451 D456 V457 M458 A463 G464 L465 L466F451-A460 HydrophobicContact CE1-CB 3.7Å; F451-A460 HydrophobicContact CZ-CB 3.68Å; D456-A460 PolarHBondContact O-N 2.96Å; V457-A460 PolarHBondContact O-N 3.41Å; M458-A460 VanDerWaalsContact C-N 3.29Å; M458-A460 PolarHBondContact O-N 3.43Å; A460-A463 PolarHBondContact O-N 2.85Å; A460-G464 PolarHBondContact O-N 3.4Å; A460-L465 HydrophobicContact CB-CB 4.41Å; A460-L465 HydrophobicContact CB-CD1 4.35Å; A460-L465 WeakPolarHBondContact O-CB 3.31Å; A460-L465 PolarHBondContact O-N 3.25Å; A460-L466 HydrophobicContact CB-CD1 4.46Å; A460-L466 HydrophobicContact CB-CG 4.32Å
461F96.8Very high96.2Very high12 Ų1249.8 Ų49.85%0.05327%0.269CS..Hα-helixtrans-62.9-47.7172.6172.1-99.4000111.7V457 M458 A463 G464 L466 P493 V496 L497V457-F461 WeakPolarHBondContact O-CB 3.37Å; V457-F461 PolarHBondContact O-N 3.16Å; M458-F461 HydrophobicContact CE-CD1 3.77Å; M458-F461 HydrophobicContact CE-CE1 4.13Å; M458-F461 WeakPolarHBondContact O-CB 3.48Å; M458-F461 PolarHBondContact O-N 3.41Å; M458-F461 VanDerWaalsContact O-N 3.14Å; M458-F461 HydrophobicContact SD-CD1 3.99Å; F461-A463 VanDerWaalsContact C-N 3.27Å; F461-A463 PolarHBondContact O-N 2.9Å; F461-G464 PolarHBondContact O-N 2.81Å; F461-L466 HydrophobicContact CB-CD1 4.17Å; F461-P493 HydrophobicContact CB-CB 3.99Å; F461-P493 HydrophobicContact CD1-CB 3.93Å; F461-P493 HydrophobicContact CD2-CB 3.78Å; F461-P493 HydrophobicContact CE1-CB 4.37Å; F461-P493 HydrophobicContact CE2-CB 4.24Å; F461-P493 HydrophobicContact CG-CB 3.61Å; F461-V496 HydrophobicContact CE2-CB 4.16Å; F461-V496 HydrophobicContact CE2-CG1 4.09Å; F461-V496 HydrophobicContact CZ-CB 3.97Å; F461-V496 HydrophobicContact CZ-CG1 3.76Å; F461-L497 HydrophobicContact CD2-CD1 4.27Å; F461-L497 HydrophobicContact CD2-CD2 3.93Å; F461-L497 HydrophobicContact CD2-CG 3.96Å; F461-L497 HydrophobicContact CE2-CD2 3.81Å; F461-L497 HydrophobicContact CE2-CG 3.91Å
462E95.6Very high96.3Very high139 Ų13948.8 Ų48.865%0.6526%0.264SS*.Hα-helixtrans-62.3-34.5178.3-71.2172.7177.900112.4M458 P459 G464M458-E462 HydrophobicContact CE-CG 3.94Å; M458-E462 WeakPolarHBondContact CE-OE1 3.47Å; M458-E462 WeakPolarHBondContact O-CG 3.34Å; M458-E462 PolarHBondContact O-N 2.91Å; P459-E462 PolarHBondContact O-N 3.01Å; E462-G464 PolarHBondContact O-N 3.32Å
463A96.6Very high96.5Very high71 Ų7146 Ų4659%0.58725%0.252SS*.THydrogen-bonded Turntrans-76.5-2.2175.100000114.1P459 A460 F461 L465P459-A463 WeakPolarHBondContact O-CB 3.46Å; P459-A463 PolarHBondContact O-N 3.23Å; A460-A463 PolarHBondContact O-N 2.85Å; F461-A463 VanDerWaalsContact C-N 3.27Å; F461-A463 PolarHBondContact O-N 2.9Å; A463-L465 HydrophobicContact CB-CD1 4.25Å; A463-L465 HydrophobicContact CB-CG 3.98Å; A463-L465 PolarHBondContact O-N 3.02Å
464G96.2Very high96.7Very high29 Ų2944.3 Ų44.330%0.29924%0.239SC..THydrogen-bonded Turntrans72.510.8-17800000114.4A460 F461 E462 L466 D467A460-G464 PolarHBondContact O-N 3.4Å; F461-G464 PolarHBondContact O-N 2.81Å; E462-G464 PolarHBondContact O-N 3.32Å; G464-L466 PolarHBondContact O-N 3.07Å; G464-D467 PolarHBondContact O-N 2.86Å
465L96.4Very high96.9Very high109 Ų10944.5 Ų44.557%0.57124%0.24SC*.THydrogen-bonded Turntrans-69.2-18.4-178.1-61.4177.5000113A460 A463 R468A460-L465 HydrophobicContact CB-CB 4.41Å; A460-L465 HydrophobicContact CB-CD1 4.35Å; A460-L465 WeakPolarHBondContact O-CB 3.31Å; A460-L465 PolarHBondContact O-N 3.25Å; A463-L465 HydrophobicContact CB-CD1 4.25Å; A463-L465 HydrophobicContact CB-CG 3.98Å; A463-L465 PolarHBondContact O-N 3.02Å; L465-R468 PolarHBondContact O-NE 3.47Å
466L97.8Very high97Very high0 Ų041 Ų410%022%0.223CC..THydrogen-bonded Turntrans-101.23.4178.4-56.8-178000113.4V449 F451 V457 A460 F461 G464 R468 V472 L497V449-L466 HydrophobicContact CB-CD2 4.16Å; V449-L466 HydrophobicContact CG1-CD2 3.84Å; V449-L466 HydrophobicContact CG2-CD2 4.22Å; F451-L466 HydrophobicContact CE2-CD2 4.25Å; F451-L466 HydrophobicContact CZ-CD2 4.1Å; V457-L466 HydrophobicContact CG1-CD1 3.99Å; A460-L466 HydrophobicContact CB-CD1 4.46Å; A460-L466 HydrophobicContact CB-CG 4.32Å; F461-L466 HydrophobicContact CB-CD1 4.17Å; G464-L466 PolarHBondContact O-N 3.07Å; L466-R468 PolarHBondContact O-N 3.25Å; L466-V472 HydrophobicContact CD2-CG2 4.33Å; L466-L497 HydrophobicContact CB-CD1 3.58Å; L466-L497 HydrophobicContact CB-CD2 4.34Å; L466-L497 HydrophobicContact CD1-CD1 4.26Å; L466-L497 WeakPolarHBondContact O-CD2 3.22Å
467D97.2Very high97.2Very high66 Ų6637.9 Ų37.935%0.35321%0.206SC..SBendtrans-76.156.3177.7-74.2-27.9000111.5G464 L497 R500 F502G464-D467 PolarHBondContact O-N 2.86Å; D467-L497 WeakPolarHBondContact OD1-CD2 3.35Å; D467-R500 IonicContact OD1-NH1 3.46Å; D467-R500 PolarHBondContact OD1-NH1 3.41Å; D467-R500 IonicContact OD2-NH1 2.62Å; D467-F502 VanDerWaalsContact C-CE1 3.45Å; D467-F502 HydrophobicContact CB-CE2 3.88Å; D467-F502 HydrophobicContact CB-CZ 3.86Å; D467-F502 WeakPolarHBondContact O-CE1 3.45Å; D467-F502 VanDerWaalsContact O-CZ 3.23Å; D467-F502 WeakPolarHBondContact O-CZ 3.41Å
468R97.9Very high97.3Very high132 Ų13237.8 Ų37.850%0.49821%0.206SC..SBendtrans-162.1163.5178.859.1-176.4176.7172.84.6110.4L465 L466 C470 I504L465-R468 PolarHBondContact O-NE 3.47Å; L466-R468 PolarHBondContact O-N 3.25Å; R468-C470 PolarHBondContact O-N 3.4Å; R468-C470 PolarHBondContact O-SG 3.46Å; R468-C470 VanDerWaalsContact O-SG 3.41Å; R468-I504 WeakPolarHBondContact O-CD1 3.46Å
469D98.4Very high97.5Very high78 Ų7835.7 Ų35.742%0.41720%0.196SC..SBendtrans-60.4125.4169-64.7-6.4000109.5A446 F502 K503A446-D469 HydrophobicContact CB-CB 4.38Å; D469-F502 WeakPolarHBondContact OD1-CA 3.39Å; D469-K503 WeakPolarHBondContact CA-O 3.3Å; D469-K503 HydrophobicContact CB-CB 4.09Å; D469-K503 PolarHBondContact OD1-N 3.48Å
470C98.5Very high97.5Very high1 Ų134.6 Ų34.61%0.00718%0.184CC..EExtended strand (participates in β ladder)trans-160.5157-17858.90000113.3P447 V449 R468 K503 I504 A505P447-C470 CarbonylContact O-C 3.59Å; P447-C470 VanDerWaalsContact O-CA 3.28Å; P447-C470 WeakPolarHBondContact O-CA 3.49Å; P447-C470 WeakPolarHBondContact O-CB 3.46Å; V449-C470 HydrophobicContact CG2-CB 3.88Å; R468-C470 PolarHBondContact O-N 3.4Å; R468-C470 PolarHBondContact O-SG 3.46Å; R468-C470 VanDerWaalsContact O-SG 3.41Å; C470-K503 PolarHBondContact N-O 2.93Å; C470-I504 WeakPolarHBondContact O-CA 3.41Å; C470-I504 WeakPolarHBondContact SG-CD1 3.41Å; C470-A505 PolarHBondContact O-N 3.25Å
471V98.7Very high97.5Very high0 Ų034.1 Ų34.10%018%0.18CC..EExtended strand (participates in β ladder)trans-101.9108.4165.1-178.30000108I444 A446 P447 A448 V449 V473 A505 V507 I544 V546I444-V471 HydrophobicContact CG2-CG2 4.23Å; A446-V471 HydrophobicContact CB-CG2 4.12Å; P447-V471 PolarHBondContact O-N 2.89Å; A448-V471 CarbonylContact C-O 3.43Å; A448-V471 VanDerWaalsContact CA-O 3.29Å; A448-V471 WeakPolarHBondContact CA-O 3.16Å; V449-V471 PolarHBondContact N-O 3.02Å; V471-V473 HydrophobicContact CG1-CG2 4.16Å; V471-V473 PolarHBondContact O-N 3.25Å; V471-A505 CarbonylContact C-O 3.58Å; V471-A505 WeakPolarHBondContact CA-O 3.38Å; V471-A505 HydrophobicContact CG1-CB 4.42Å; V471-A505 HydrophobicContact CG2-CB 4.31Å; V471-V507 HydrophobicContact CG1-CB 4.27Å; V471-V507 HydrophobicContact CG1-CG2 3.49Å; V471-V507 VanDerWaalsContact CG1-CG2 3.49Å; V471-I544 HydrophobicContact CB-CB 4.16Å; V471-I544 HydrophobicContact CB-CD1 4.5Å; V471-I544 HydrophobicContact CG1-CB 4.15Å; V471-I544 HydrophobicContact CG1-CD1 4.14Å; V471-I544 HydrophobicContact CG1-CG2 4.1Å; V471-I544 HydrophobicContact CG2-CB 4.01Å; V471-I544 HydrophobicContact CG2-CG2 4.4Å; V471-V546 HydrophobicContact CG1-CG2 4.41Å
472V98.5Very high97.5Very high0 Ų033.7 Ų33.70%018%0.178CC..EExtended strand (participates in β ladder)trans-74.1118174175.30000108F451 V457 L466 V474 L494 A505 L506 V507F451-V472 HydrophobicContact CD2-CG1 3.84Å; F451-V472 HydrophobicContact CE2-CG1 3.89Å; V457-V472 HydrophobicContact CG2-CG1 4.39Å; L466-V472 HydrophobicContact CD2-CG2 4.33Å; V472-V474 HydrophobicContact CG1-CG2 4.11Å; V472-L494 HydrophobicContact CB-CD2 4.29Å; V472-L494 HydrophobicContact CG2-CD2 3.72Å; V472-A505 PolarHBondContact N-O 3.22Å; V472-L506 HydrophobicContact CB-CD1 4.48Å; V472-L506 HydrophobicContact CG1-CD1 4.2Å; V472-L506 CarbonylContact O-C 3.55Å; V472-L506 WeakPolarHBondContact O-CA 3.42Å; V472-L506 WeakPolarHBondContact O-CD1 3.43Å; V472-V507 PolarHBondContact O-N 3.04Å
473V98.7Very high97.6Very high0 Ų027.1 Ų27.10%015%0.147CC..EExtended strand (participates in β ladder)trans-107.8120179.8-179.60000108.2A448 V449 V450 F451 V471 V507 L535 V538 I544A448-V473 HydrophobicContact CB-CG2 4.09Å; V449-V473 PolarHBondContact O-N 3.27Å; V450-V473 CarbonylContact C-O 3.59Å; V450-V473 HydrophobicContact CG2-CB 4.3Å; F451-V473 PolarHBondContact N-O 3.48Å; V471-V473 HydrophobicContact CG1-CG2 4.16Å; V471-V473 PolarHBondContact O-N 3.25Å; V473-V507 WeakPolarHBondContact CA-O 3.27Å; V473-V507 HydrophobicContact CG2-CB 4.36Å; V473-L535 HydrophobicContact CG1-CD1 3.7Å; V473-L535 HydrophobicContact CG1-CG 4.38Å; V473-V538 HydrophobicContact CG2-CG1 4.27Å; V473-I544 HydrophobicContact CG2-CD1 3.55Å
474V98.1Very high97.6Very high0 Ų023.7 Ų23.70%012%0.119CC..EExtended strand (participates in β ladder)trans-119103.9173.9-167.10000108F451 V457 V472 Q477 L487 L490 L506 V507 T508F451-V474 HydrophobicContact CB-CG2 4.35Å; F451-V474 WeakPolarHBondContact O-CA 3.3Å; V457-V474 HydrophobicContact CG2-CG2 4.35Å; V472-V474 HydrophobicContact CG1-CG2 4.11Å; V474-Q477 HydrophobicContact CG1-CG 3.75Å; V474-L487 HydrophobicContact CB-CD1 4.3Å; V474-L487 HydrophobicContact CG1-CD1 4.21Å; V474-L490 HydrophobicContact CG2-CD1 3.9Å; V474-L490 HydrophobicContact CG2-CD2 4.31Å; V474-L506 HydrophobicContact CG2-CD1 3.98Å; V474-V507 PolarHBondContact N-O 3.41Å; V474-T508 VanDerWaalsContact O-CA 3.28Å; V474-T508 WeakPolarHBondContact O-CA 3.29Å; V474-T508 WeakPolarHBondContact O-CB 3.25Å; V474-T508 PolarHBondContact O-OG1 3.35Å
475R97.3Very high97.6Very high18 Ų1822.5 Ų22.57%0.06811%0.106CC..  trans-103.7172-174.261.4172-179.8-147.6-7.1112.1V450 F451 E452 Q477 D509 A529 L535 A536 V538 H568V450-R475 HydrophobicContact CG1-CG 4.48Å; F451-R475 PolarHBondContact O-N 2.87Å; F451-R475 VanDerWaalsContact O-N 3.17Å; E452-R475 IonicContact OE1-CZ 3.39Å; E452-R475 IonicContact OE1-NE 3.57Å; E452-R475 PolarHBondContact OE1-NE 3.36Å; E452-R475 IonicContact OE1-NH2 3.17Å; E452-R475 PolarHBondContact OE1-NH2 3.22Å; E452-R475 WeakPolarHBondContact OE2-CG 3.42Å; E452-R475 IonicContact OE2-NE 2.76Å; E452-R475 PolarHBondContact OE2-NE 3.16Å; R475-Q477 PolarHBondContact O-N 3.47Å; R475-Q477 PolarHBondContact O-NE2 3.38Å; R475-Q477 VanDerWaalsContact O-NE2 3.14Å; R475-D509 WeakPolarHBondContact CA-OD1 3.25Å; R475-A529 HydrophobicContact CB-CB 3.97Å; R475-L535 HydrophobicContact CB-CD2 3.89Å; R475-L535 HydrophobicContact CB-CG 3.95Å; R475-A536 PolarHBondContact NH1-O 2.83Å; R475-V538 PolarHBondContact NH1-O 3.39Å; R475-H568 VanDerWaalsContact NH2-CB 3.32Å; R475-H568 PolarHBondContact NH2-CD2 3.17Å; R475-H568 VanDerWaalsContact NH2-CG 3.31Å
476H97.2Very high97.5Very high2 Ų217.4 Ų17.41%0.0098%0.079CC..SBendtrans59.932.5-176.4-52.9112000112.7E452 A481 D509 A529 H568 P570 L572E452-H476 IonicContact OE2-CE1 3.25Å; E452-H476 IonicContact OE2-CG 3.51Å; E452-H476 IonicContact OE2-ND1 3.51Å; E452-H476 PolarHBondContact OE2-ND1 2.63Å; H476-A481 VanDerWaalsContact C-CB 3.41Å; H476-A481 HydrophobicContact CB-CB 4.27Å; H476-A481 WeakPolarHBondContact O-CB 3.28Å; H476-D509 PolarHBondContact N-OD1 2.86Å; H476-D509 VanDerWaalsContact N-OD1 3.13Å; H476-D509 PolarHBondContact N-OD2 3.48Å; H476-A529 WeakPolarHBondContact NE2-CB 3.5Å; H476-H568 AromaticContact CE1-CD2 3.85Å; H476-P570 HydrophobicContact CB-CB 4.44Å; H476-P570 HydrophobicContact CB-CG 4.14Å; H476-P570 WeakPolarHBondContact NE2-CD 3.31Å; H476-L572 HydrophobicContact CB-CD2 4.42Å
477Q97.6Very high97.4Very high9 Ų917.4 Ų17.44%0.0428%0.079CC..  trans-107.911.8174.5-54.2-54.2-54.100111.5E452 V474 R475 N482 M484 L487 D509 G510E452-Q477 PolarHBondContact O-NE2 2.88Å; V474-Q477 HydrophobicContact CG1-CG 3.75Å; R475-Q477 PolarHBondContact O-N 3.47Å; R475-Q477 PolarHBondContact O-NE2 3.38Å; R475-Q477 VanDerWaalsContact O-NE2 3.14Å; Q477-N482 WeakPolarHBondContact CA-OD1 3.44Å; Q477-N482 PolarHBondContact O-OD1 3.47Å; Q477-N482 PolarHBondContact OE1-ND2 2.91Å; Q477-M484 VanDerWaalsContact O-CA 3.24Å; Q477-M484 WeakPolarHBondContact O-CA 3.33Å; Q477-M484 WeakPolarHBondContact O-CG 3.46Å; Q477-L487 HydrophobicContact CB-CD1 4.17Å; Q477-L487 HydrophobicContact CB-CD2 4.35Å; Q477-L487 HydrophobicContact CG-CD1 3.89Å; Q477-L487 HydrophobicContact CG-CD2 4.07Å; Q477-D509 WeakPolarHBondContact CA-OD1 3.36Å; Q477-D509 PolarHBondContact N-OD1 3.35Å; Q477-G510 WeakPolarHBondContact O-CA 3.39Å; Q477-G510 PolarHBondContact O-N 3.09Å
478G97.8Very high97Very high0 Ų015.9 Ų15.90%07%0.07CC..SBendtrans-73.8176.4-178.100000115K480 A481 N482 G483 M484 D509 E528G478-K480 PolarHBondContact O-N 3.41Å; G478-A481 PolarHBondContact O-N 2.94Å; G478-N482 PolarHBondContact O-N 3.25Å; G478-G483 PolarHBondContact O-N 3.23Å; G478-M484 PolarHBondContact O-N 3.19Å; G478-M484 VanDerWaalsContact O-N 3.15Å; G478-D509 WeakPolarHBondContact CA-O 3.29Å; G478-E528 WeakPolarHBondContact CA-OE2 3.37Å
479P98.1Very high96.6Very high2 Ų213.6 Ų13.61%0.0136%0.064CC..Hα-helixtrans-49.4-53.9177.8-27.633.6000113.9G483 M484 E528 R588 L591 A598P479-G483 WeakPolarHBondContact O-CA 3.36Å; P479-G483 PolarHBondContact O-N 3.33Å; P479-M484 HydrophobicContact CG-CB 4.36Å; P479-M484 HydrophobicContact CG-CG 4.38Å; P479-M484 HydrophobicContact CG-SD 3.73Å; P479-E528 VanDerWaalsContact CD-OE1 3.23Å; P479-E528 WeakPolarHBondContact CD-OE1 3.49Å; P479-R588 WeakPolarHBondContact O-CG 3.25Å; P479-L591 HydrophobicContact CB-CB 3.7Å; P479-L591 HydrophobicContact CB-CD1 3.91Å; P479-L591 HydrophobicContact CB-CG 4.43Å; P479-L591 WeakPolarHBondContact O-CD1 3.46Å; P479-A598 HydrophobicContact CB-CB 4.25Å; P479-A598 HydrophobicContact CG-CB 3.81Å
480K97.7Very high96.4Very high48 Ų489.9 Ų9.921%0.2094%0.044CC..Hα-helixtrans-79.2-31.6-177.5-66.2178.5-176162.40112.2G478 E528 Y530 D531 R576 R588 L591G478-K480 PolarHBondContact O-N 3.41Å; K480-E528 WeakPolarHBondContact CB-OE1 3.22Å; K480-E528 PolarHBondContact N-OE1 3.04Å; K480-E528 PolarHBondContact N-OE2 3.26Å; K480-Y530 HydrophobicContact CB-CD1 3.65Å; K480-Y530 HydrophobicContact CB-CE1 3.94Å; K480-D531 VanDerWaalsContact CD-OD1 3.31Å; K480-D531 WeakPolarHBondContact CD-OD1 2.97Å; K480-D531 WeakPolarHBondContact CE-OD2 3.24Å; K480-D531 IonicContact NZ-OD1 3.7Å; K480-D531 PolarHBondContact NZ-OD1 2.93Å; K480-D531 IonicContact NZ-OD2 2.75Å; K480-D531 PolarHBondContact NZ-OD2 3.48Å; K480-R576 PolarHBondContact O-NH2 2.71Å; K480-R588 WeakPolarHBondContact O-CD 3.33Å; K480-L591 WeakPolarHBondContact CE-O 3.28Å
481A97.1Very high96.1Very high0 Ų011.2 Ų11.20%05%0.051CC..Hα-helixtrans-58.6-56.7179.300000111.6H476 G478 E528 Y530 L572 R576H476-A481 VanDerWaalsContact C-CB 3.41Å; H476-A481 HydrophobicContact CB-CB 4.27Å; H476-A481 WeakPolarHBondContact O-CB 3.28Å; G478-A481 PolarHBondContact O-N 2.94Å; A481-E528 VanDerWaalsContact CB-OE2 3.31Å; A481-E528 WeakPolarHBondContact CB-OE2 3.33Å; A481-E528 PolarHBondContact N-OE2 2.87Å; A481-Y530 HydrophobicContact CB-CG 4.27Å; A481-L572 HydrophobicContact CB-CD1 4.24Å; A481-R576 PolarHBondContact O-NH1 2.73Å; A481-R576 PolarHBondContact O-NH2 3.49Å
482N96.9Very high95.7Very high4 Ų412.6 Ų12.62%0.0216%0.059CC..Hα-helixtrans-151.727.1-177.965.3-6.6000113.7E123 Q477 G478 M484 P485E123-N482 WeakPolarHBondContact CA-O 3.4Å; E123-N482 WeakPolarHBondContact CB-O 3.32Å; E123-N482 HydrophobicContact CG-CB 4.28Å; E123-N482 WeakPolarHBondContact CG-O 3.4Å; Q477-N482 WeakPolarHBondContact CA-OD1 3.44Å; Q477-N482 PolarHBondContact O-OD1 3.47Å; Q477-N482 PolarHBondContact OE1-ND2 2.91Å; G478-N482 PolarHBondContact O-N 3.25Å; N482-M484 VanDerWaalsContact C-N 3.29Å; N482-M484 PolarHBondContact O-N 2.86Å; N482-P485 WeakPolarHBondContact OD1-CD 3.5Å
483G97Very high95.5Very high0 Ų012.7 Ų12.70%06%0.06CC..SBendtrans78.413.6178.600000114.1L126 G478 P479L126-G483 WeakPolarHBondContact CB-O 3.24Å; G478-G483 PolarHBondContact O-N 3.23Å; P479-G483 WeakPolarHBondContact O-CA 3.36Å; P479-G483 PolarHBondContact O-N 3.33Å
484M97.5Very high95.3Very high0 Ų012.7 Ų12.70%06%0.06CC..  trans5663.3174.7-146.1-173.775.500114.8L126 M305 Q477 G478 P479 N482 R511 A594L126-M484 HydrophobicContact CD2-CB 3.91Å; L126-M484 HydrophobicContact CD2-CE 3.72Å; L126-M484 HydrophobicContact CD2-SD 4.27Å; M305-M484 HydrophobicContact CE-CE 3.25Å; M305-M484 HydrophobicContact SD-CE 3.18Å; M305-M484 WeakPolarHBondContact SD-CE 3.31Å; M305-M484 HydrophobicContact SD-SD 3.84Å; Q477-M484 VanDerWaalsContact O-CA 3.24Å; Q477-M484 WeakPolarHBondContact O-CA 3.33Å; Q477-M484 WeakPolarHBondContact O-CG 3.46Å; G478-M484 PolarHBondContact O-N 3.19Å; G478-M484 VanDerWaalsContact O-N 3.15Å; P479-M484 HydrophobicContact CG-CB 4.36Å; P479-M484 HydrophobicContact CG-CG 4.38Å; P479-M484 HydrophobicContact CG-SD 3.73Å; N482-M484 VanDerWaalsContact C-N 3.29Å; N482-M484 PolarHBondContact O-N 2.86Å; M484-R511 HydrophobicContact CE-CB 4Å; M484-R511 HydrophobicContact CE-CG 3.83Å; M484-R511 HydrophobicContact CG-CG 4.33Å; M484-R511 PolarHBondContact O-NE 2.91Å; M484-R511 PolarHBondContact O-NH2 3.46Å; M484-A594 HydrophobicContact SD-CB 4.39Å
485P96Very high95Very high3 Ų312.9 Ų12.92%0.0196%0.062CC..  trans-64.9155.5179.129.6-35000111.7M122 E123 N482 L487 R511M122-P485 HydrophobicContact CB-CB 3.99Å; M122-P485 HydrophobicContact CG-CB 3.78Å; E123-P485 HydrophobicContact CG-CB 4.33Å; E123-P485 HydrophobicContact CG-CG 4.26Å; N482-P485 WeakPolarHBondContact OD1-CD 3.5Å; P485-L487 HydrophobicContact CG-CD2 3.98Å; P485-R511 VanDerWaalsContact O-CG 3.3Å; P485-R511 WeakPolarHBondContact O-CG 3.34Å
486E94.7Very high94.8Very high2 Ų212.3 Ų12.31%0.0096%0.06CC..BIsolated β-bridgetrans-77.3122.3164.5-64.9-178.9173.700109.9M122 K156 N302 H488 R511 S513M122-E486 HydrophobicContact CE-CB 3.48Å; M122-E486 VanDerWaalsContact CE-CB 3.48Å; M122-E486 HydrophobicContact CE-CG 3.45Å; M122-E486 VanDerWaalsContact CE-CG 3.45Å; K156-E486 IonicContact NZ-OE1 3.21Å; N302-E486 PolarHBondContact ND2-OE1 3.32Å; E486-H488 PolarHBondContact O-N 3.3Å; E486-R511 WeakPolarHBondContact CA-O 3.4Å; E486-R511 HydrophobicContact CG-CG 3.88Å; E486-S513 VanDerWaalsContact CD-CA 3.48Å; E486-S513 VanDerWaalsContact OE2-CA 3.26Å; E486-S513 WeakPolarHBondContact OE2-CA 3.39Å; E486-S513 WeakPolarHBondContact OE2-CB 3.47Å
487L94.8Very high94.7Very high0 Ų012.2 Ų12.20%06%0.06CC..  trans-84.759-174.6-50.1177.3000111.5Q454 V474 Q477 P485 K489 L490 T508 R511 L512Q454-L487 HydrophobicContact CB-CB 4.29Å; Q454-L487 HydrophobicContact CB-CD2 4.22Å; Q454-L487 HydrophobicContact CG-CD2 4.47Å; V474-L487 HydrophobicContact CB-CD1 4.3Å; V474-L487 HydrophobicContact CG1-CD1 4.21Å; Q477-L487 HydrophobicContact CB-CD1 4.17Å; Q477-L487 HydrophobicContact CB-CD2 4.35Å; Q477-L487 HydrophobicContact CG-CD1 3.89Å; Q477-L487 HydrophobicContact CG-CD2 4.07Å; P485-L487 HydrophobicContact CG-CD2 3.98Å; L487-K489 VanDerWaalsContact C-N 3.26Å; L487-K489 PolarHBondContact O-N 3.49Å; L487-L490 HydrophobicContact CB-CD1 3.5Å; L487-L490 HydrophobicContact CB-CG 3.89Å; L487-L490 HydrophobicContact CD1-CD1 3.82Å; L487-L490 HydrophobicContact CG-CD1 4.32Å; L487-L490 WeakPolarHBondContact O-CB 3.26Å; L487-L490 WeakPolarHBondContact O-CG 3.35Å; L487-L490 PolarHBondContact O-N 3.18Å; L487-T508 HydrophobicContact CD1-CG2 4.15Å; L487-T508 WeakPolarHBondContact CD1-OG1 3.24Å; L487-R511 PolarHBondContact N-O 2.93Å; L487-L512 HydrophobicContact CB-CD2 4.08Å
488H88.4Confident94.5Very high35 Ų3512.6 Ų12.616%0.1626%0.062CC..G310 helixtrans-59.2-33.1-171-173.664.3000114Q117 R194 E486 L490 M491Q117-H488 HydrophobicContact CB-CB 4.05Å; Q117-H488 HydrophobicContact CG-CB 3.91Å; R194-H488 PolarHBondContact NH1-CE1 3.26Å; R194-H488 VanDerWaalsContact NH1-CE1 3.27Å; R194-H488 PolarHBondContact NH1-NE2 3.45Å; E486-H488 PolarHBondContact O-N 3.3Å; H488-L490 PolarHBondContact O-N 3.42Å; H488-L490 VanDerWaalsContact O-N 3.15Å; H488-M491 PolarHBondContact O-N 2.72Å
489K90.3Very high94.2Very high84 Ų8417 Ų1737%0.3659%0.086SC..G310 helixtrans-67.1-14.9-177-67-174.8177.8171.50113.6G118 Q454 H455 L487 P493G118-K489 WeakPolarHBondContact O-CE 3.47Å; G118-K489 PolarHBondContact O-NZ 2.82Å; Q454-K489 HydrophobicContact CG-CB 4.49Å; H455-K489 PolarHBondContact CE1-NZ 3.38Å; L487-K489 VanDerWaalsContact C-N 3.26Å; L487-K489 PolarHBondContact O-N 3.49Å; K489-P493 VanDerWaalsContact O-CD 3.29Å; K489-P493 WeakPolarHBondContact O-CD 3.47Å
490L93.7Very high94Very high0 Ų021.9 Ų21.90%010%0.104CC..G310 helixtrans-73.8-33.1179.6-58-176.2000112.7Q454 V457 V474 L487 H488 P493 L494 L506Q454-L490 HydrophobicContact CB-CD2 3.79Å; Q454-L490 HydrophobicContact CB-CG 4.07Å; V457-L490 HydrophobicContact CB-CD2 3.75Å; V457-L490 HydrophobicContact CG1-CD2 3.99Å; V457-L490 HydrophobicContact CG2-CD2 3.47Å; V457-L490 VanDerWaalsContact CG2-CD2 3.47Å; V474-L490 HydrophobicContact CG2-CD1 3.9Å; V474-L490 HydrophobicContact CG2-CD2 4.31Å; L487-L490 HydrophobicContact CB-CD1 3.5Å; L487-L490 HydrophobicContact CB-CG 3.89Å; L487-L490 HydrophobicContact CD1-CD1 3.82Å; L487-L490 HydrophobicContact CG-CD1 4.32Å; L487-L490 WeakPolarHBondContact O-CB 3.26Å; L487-L490 WeakPolarHBondContact O-CG 3.35Å; L487-L490 PolarHBondContact O-N 3.18Å; H488-L490 PolarHBondContact O-N 3.42Å; H488-L490 VanDerWaalsContact O-N 3.15Å; L490-P493 WeakPolarHBondContact O-CD 3.32Å; L490-P493 WeakPolarHBondContact O-CG 3.17Å; L490-L494 HydrophobicContact CB-CD1 4.18Å; L490-L494 WeakPolarHBondContact O-CB 3.23Å; L490-L494 WeakPolarHBondContact O-CG 3.41Å; L490-L494 PolarHBondContact O-N 3.41Å; L490-L506 HydrophobicContact CD1-CD1 3.79Å; L490-L506 HydrophobicContact CD1-CD2 3.92Å
491M91.4Very high93.8Very high29 Ų2925 Ų2514%0.14313%0.131CC..Hα-helixtrans-68.3-42.8-167-63.5-63.795.600114.3H488 L494 G495 L506 L512H488-M491 PolarHBondContact O-N 2.72Å; M491-L494 HydrophobicContact CE-CD1 4.09Å; M491-G495 PolarHBondContact O-N 3.47Å; M491-L506 HydrophobicContact CE-CD2 3.96Å; M491-L512 HydrophobicContact CE-CD1 3.61Å; M491-L512 HydrophobicContact CE-CD2 3.7Å; M491-L512 HydrophobicContact CE-CG 4.31Å; M491-L512 HydrophobicContact CG-CD2 4.49Å; M491-L512 HydrophobicContact SD-CD1 3.76Å; M491-L512 HydrophobicContact SD-CD2 4.31Å
492P90.4Very high93.8Very high28 Ų2827.4 Ų27.418%0.18214%0.141CC..Hα-helixtrans-59.3-55177.6-22.733.6000114.4A198 L494 G495 V496A198-P492 HydrophobicContact CB-CB 4.17Å; P492-L494 PolarHBondContact O-N 3.27Å; P492-G495 PolarHBondContact O-N 3.45Å; P492-V496 WeakPolarHBondContact O-CG2 3.47Å; P492-V496 PolarHBondContact O-N 3.05Å; P492-V496 VanDerWaalsContact O-N 3.08Å
493P94.1Very high93.8Very high2 Ų230.8 Ų30.81%0.01316%0.156CC..Hα-helixtrans-64.5-43.1-178.224.1-33.1000112.3V457 M458 F461 K489 L490 G495 V496 L497V457-P493 HydrophobicContact CG1-CG 4.5Å; M458-P493 HydrophobicContact SD-CB 4.09Å; M458-P493 HydrophobicContact SD-CG 4.17Å; F461-P493 HydrophobicContact CB-CB 3.99Å; F461-P493 HydrophobicContact CD1-CB 3.93Å; F461-P493 HydrophobicContact CD2-CB 3.78Å; F461-P493 HydrophobicContact CE1-CB 4.37Å; F461-P493 HydrophobicContact CE2-CB 4.24Å; F461-P493 HydrophobicContact CG-CB 3.61Å; K489-P493 VanDerWaalsContact O-CD 3.29Å; K489-P493 WeakPolarHBondContact O-CD 3.47Å; L490-P493 WeakPolarHBondContact O-CD 3.32Å; L490-P493 WeakPolarHBondContact O-CG 3.17Å; P493-G495 VanDerWaalsContact C-N 3.27Å; P493-G495 PolarHBondContact O-N 3.15Å; P493-V496 WeakPolarHBondContact O-CB 3.37Å; P493-V496 PolarHBondContact O-N 3.42Å; P493-V496 VanDerWaalsContact O-N 3.1Å; P493-L497 WeakPolarHBondContact O-CG 3.38Å; P493-L497 PolarHBondContact O-N 3.3Å
494L95Very high93.8Very high0 Ų030.8 Ų30.80%016%0.156CC..Hα-helixtrans-63.8-35.3177.1-59.2-178.5000111.9V472 L490 M491 P492 V496 L497 L498 I504 L506 V519V472-L494 HydrophobicContact CB-CD2 4.29Å; V472-L494 HydrophobicContact CG2-CD2 3.72Å; L490-L494 HydrophobicContact CB-CD1 4.18Å; L490-L494 WeakPolarHBondContact O-CB 3.23Å; L490-L494 WeakPolarHBondContact O-CG 3.41Å; L490-L494 PolarHBondContact O-N 3.41Å; M491-L494 HydrophobicContact CE-CD1 4.09Å; P492-L494 PolarHBondContact O-N 3.27Å; L494-V496 VanDerWaalsContact C-N 3.33Å; L494-V496 PolarHBondContact O-N 3.47Å; L494-L497 HydrophobicContact CD2-CD1 4.17Å; L494-L497 PolarHBondContact O-N 3.17Å; L494-L498 PolarHBondContact O-N 3.17Å; L494-L498 VanDerWaalsContact O-N 3.13Å; L494-I504 HydrophobicContact CB-CG2 4.34Å; L494-I504 HydrophobicContact CD2-CG2 3.87Å; L494-L506 HydrophobicContact CD1-CB 4.33Å; L494-V519 HydrophobicContact CB-CG1 4.25Å; L494-V519 HydrophobicContact CB-CG2 3.94Å; L494-V519 HydrophobicContact CD1-CG1 4.22Å
495G91.7Very high93.8Very high5 Ų530.8 Ų30.85%0.05216%0.156CC..Hα-helixtrans-62.7-38.2173.500000113.1M491 P492 P493 D499 K518M491-G495 PolarHBondContact O-N 3.47Å; P492-G495 PolarHBondContact O-N 3.45Å; P493-G495 VanDerWaalsContact C-N 3.27Å; P493-G495 PolarHBondContact O-N 3.15Å; G495-D499 PolarHBondContact O-N 3.43Å; G495-D499 VanDerWaalsContact O-N 3.16Å; G495-D499 VanDerWaalsContact O-OD2 3.13Å; G495-K518 WeakPolarHBondContact O-CE 3.47Å; G495-K518 PolarHBondContact O-NZ 3.27Å
496V93.4Very high93.9Very high5 Ų530.7 Ų30.73%0.0316%0.155CC..Hα-helixtrans-67.8-42.3175.11740000111.2Q195 E199 F461 P492 P493 L494 L498 D499 R500Q195-V496 HydrophobicContact CB-CG2 4.24Å; Q195-V496 HydrophobicContact CG-CG2 4.26Å; E199-V496 HydrophobicContact CG-CG1 4.4Å; E199-V496 HydrophobicContact CG-CG2 4.28Å; F461-V496 HydrophobicContact CE2-CB 4.16Å; F461-V496 HydrophobicContact CE2-CG1 4.09Å; F461-V496 HydrophobicContact CZ-CB 3.97Å; F461-V496 HydrophobicContact CZ-CG1 3.76Å; P492-V496 WeakPolarHBondContact O-CG2 3.47Å; P492-V496 PolarHBondContact O-N 3.05Å; P492-V496 VanDerWaalsContact O-N 3.08Å; P493-V496 WeakPolarHBondContact O-CB 3.37Å; P493-V496 PolarHBondContact O-N 3.42Å; P493-V496 VanDerWaalsContact O-N 3.1Å; L494-V496 VanDerWaalsContact C-N 3.33Å; L494-V496 PolarHBondContact O-N 3.47Å; V496-L498 VanDerWaalsContact C-N 3.3Å; V496-L498 PolarHBondContact O-N 3.23Å; V496-D499 WeakPolarHBondContact O-CB 3.48Å; V496-D499 PolarHBondContact O-N 2.82Å; V496-R500 WeakPolarHBondContact O-CG 3.34Å; V496-R500 PolarHBondContact O-N 3Å
497L95.6Very high94.1Very high0 Ų030.6 Ų30.60%015%0.154CC..Hα-helixtrans-60.6-39.3177.2-66.1172.9000112.3F461 L466 D467 P493 L494 R500 C501 F502 I504F461-L497 HydrophobicContact CD2-CD1 4.27Å; F461-L497 HydrophobicContact CD2-CD2 3.93Å; F461-L497 HydrophobicContact CD2-CG 3.96Å; F461-L497 HydrophobicContact CE2-CD2 3.81Å; F461-L497 HydrophobicContact CE2-CG 3.91Å; L466-L497 HydrophobicContact CB-CD1 3.58Å; L466-L497 HydrophobicContact CB-CD2 4.34Å; L466-L497 HydrophobicContact CD1-CD1 4.26Å; L466-L497 WeakPolarHBondContact O-CD2 3.22Å; D467-L497 WeakPolarHBondContact OD1-CD2 3.35Å; P493-L497 WeakPolarHBondContact O-CG 3.38Å; P493-L497 PolarHBondContact O-N 3.3Å; L494-L497 HydrophobicContact CD2-CD1 4.17Å; L494-L497 PolarHBondContact O-N 3.17Å; L497-R500 CarbonylContact O-C 3.58Å; L497-R500 WeakPolarHBondContact O-CB 3.35Å; L497-R500 PolarHBondContact O-N 2.86Å; L497-C501 PolarHBondContact O-N 2.85Å; L497-F502 HydrophobicContact CB-CD2 4.35Å; L497-F502 HydrophobicContact CD2-CD2 4.06Å; L497-F502 HydrophobicContact CD2-CE2 4.38Å; L497-F502 PolarHBondContact O-N 3.13Å; L497-I504 HydrophobicContact CB-CD1 4.1Å; L497-I504 HydrophobicContact CB-CG1 3.7Å; L497-I504 HydrophobicContact CD1-CD1 4.03Å; L497-I504 HydrophobicContact CD1-CG1 4.32Å
498L92.7Very high94.3Very high17 Ų1730.6 Ų30.69%0.08915%0.154CC..Hα-helixtrans-64.3-38.7172.2-70.9175.5000112.6L494 V496 R500 C501 F502 I504 K518 V519L494-L498 PolarHBondContact O-N 3.17Å; L494-L498 VanDerWaalsContact O-N 3.13Å; V496-L498 VanDerWaalsContact C-N 3.3Å; V496-L498 PolarHBondContact O-N 3.23Å; L498-R500 PolarHBondContact O-N 2.75Å; L498-C501 WeakPolarHBondContact O-CA 3.31Å; L498-C501 PolarHBondContact O-N 3.09Å; L498-F502 WeakPolarHBondContact CD2-O 3.46Å; L498-I504 HydrophobicContact CD2-CB 3.94Å; L498-I504 HydrophobicContact CD2-CG1 4.32Å; L498-I504 HydrophobicContact CG-CB 4.3Å; L498-K518 HydrophobicContact CD1-CD 4.42Å; L498-K518 HydrophobicContact CD1-CG 3.9Å; L498-V519 HydrophobicContact CD1-CB 4.13Å; L498-V519 HydrophobicContact CD1-CG2 3.56Å
499D91.4Very high94.7Very high92 Ų9229 Ų2949%0.49215%0.147SC..Hα-helixtrans-66.6-23.1175.3-71.2-33.3000112.4Q195 G495 V496 C501 K518Q195-D499 PolarHBondContact NE2-OD2 3.48Å; G495-D499 PolarHBondContact O-N 3.43Å; G495-D499 VanDerWaalsContact O-N 3.16Å; G495-D499 VanDerWaalsContact O-OD2 3.13Å; V496-D499 WeakPolarHBondContact O-CB 3.48Å; V496-D499 PolarHBondContact O-N 2.82Å; D499-C501 PolarHBondContact O-N 2.71Å; D499-K518 IonicContact OD1-NZ 3.74Å; D499-K518 PolarHBondContact OD1-NZ 2.89Å; D499-K518 IonicContact OD2-NZ 3.46Å; D499-K518 PolarHBondContact OD2-NZ 3.34Å
500R94.6Very high95.1Very high106 Ų10625 Ų2540%0.413%0.129SC..THydrogen-bonded Turntrans-83.89.8169.7-64.2175.8-174.9-177.80.6113.3D467 V496 L497 L498 F502D467-R500 IonicContact OD1-NH1 3.46Å; D467-R500 PolarHBondContact OD1-NH1 3.41Å; D467-R500 IonicContact OD2-NH1 2.62Å; V496-R500 WeakPolarHBondContact O-CG 3.34Å; V496-R500 PolarHBondContact O-N 3Å; L497-R500 CarbonylContact O-C 3.58Å; L497-R500 WeakPolarHBondContact O-CB 3.35Å; L497-R500 PolarHBondContact O-N 2.86Å; L498-R500 PolarHBondContact O-N 2.75Å; R500-F502 VanDerWaalsContact C-N 3.3Å; R500-F502 HydrophobicContact CB-CD2 3.9Å; R500-F502 HydrophobicContact CB-CE2 3.91Å; R500-F502 PolarHBondContact O-N 3.39Å
501C93.9Very high95.1Very high113 Ų11325 Ų2576%0.76413%0.129SC*.THydrogen-bonded Turntrans68.315.9177.9-560000116L497 L498 D499L497-C501 PolarHBondContact O-N 2.85Å; L498-C501 WeakPolarHBondContact O-CA 3.31Å; L498-C501 PolarHBondContact O-N 3.09Å; D499-C501 PolarHBondContact O-N 2.71Å
502F96.9Very high95.1Very high51 Ų5123.6 Ų23.622%0.22412%0.123CC..  trans-73.5151.5170-63.8-61.8000111.6D467 D469 L497 L498 R500 I504D467-F502 VanDerWaalsContact C-CE1 3.45Å; D467-F502 HydrophobicContact CB-CE2 3.88Å; D467-F502 HydrophobicContact CB-CZ 3.86Å; D467-F502 WeakPolarHBondContact O-CE1 3.45Å; D467-F502 VanDerWaalsContact O-CZ 3.23Å; D467-F502 WeakPolarHBondContact O-CZ 3.41Å; D469-F502 WeakPolarHBondContact OD1-CA 3.39Å; L497-F502 HydrophobicContact CB-CD2 4.35Å; L497-F502 HydrophobicContact CD2-CD2 4.06Å; L497-F502 HydrophobicContact CD2-CE2 4.38Å; L497-F502 PolarHBondContact O-N 3.13Å; L498-F502 WeakPolarHBondContact CD2-O 3.46Å; R500-F502 VanDerWaalsContact C-N 3.3Å; R500-F502 HydrophobicContact CB-CD2 3.9Å; R500-F502 HydrophobicContact CB-CE2 3.91Å; R500-F502 PolarHBondContact O-N 3.39Å; F502-I504 HydrophobicContact CB-CD1 3.89Å; F502-I504 HydrophobicContact CB-CG1 3.95Å; F502-I504 PolarHBondContact O-N 3.42Å
503K96.6Very high94.5Very high75 Ų7522.7 Ų22.733%0.32612%0.117SC..  trans-89100.9171.3-64.6-64.3-178.1178.90109.6E440 N441 I444 D469 C470E440-K503 PolarHBondContact O-NZ 3.17Å; N441-K503 PolarHBondContact OD1-NZ 2.98Å; I444-K503 HydrophobicContact CD1-CB 3.86Å; I444-K503 HydrophobicContact CD1-CD 3.86Å; I444-K503 HydrophobicContact CD1-CG 4.41Å; D469-K503 WeakPolarHBondContact CA-O 3.3Å; D469-K503 HydrophobicContact CB-CB 4.09Å; D469-K503 PolarHBondContact OD1-N 3.48Å; C470-K503 PolarHBondContact N-O 2.93Å
504I97.4Very high93.1Very high0 Ų022.7 Ų22.70%012%0.117CC..EExtended strand (participates in β ladder)trans-117.1133.6-174.7-54.7-63.1000110.2R468 C470 L494 L497 L498 F502 P520R468-I504 WeakPolarHBondContact O-CD1 3.46Å; C470-I504 WeakPolarHBondContact O-CA 3.41Å; C470-I504 WeakPolarHBondContact SG-CD1 3.41Å; L494-I504 HydrophobicContact CB-CG2 4.34Å; L494-I504 HydrophobicContact CD2-CG2 3.87Å; L497-I504 HydrophobicContact CB-CD1 4.1Å; L497-I504 HydrophobicContact CB-CG1 3.7Å; L497-I504 HydrophobicContact CD1-CD1 4.03Å; L497-I504 HydrophobicContact CD1-CG1 4.32Å; L498-I504 HydrophobicContact CD2-CB 3.94Å; L498-I504 HydrophobicContact CD2-CG1 4.32Å; L498-I504 HydrophobicContact CG-CB 4.3Å; F502-I504 HydrophobicContact CB-CD1 3.89Å; F502-I504 HydrophobicContact CB-CG1 3.95Å; F502-I504 PolarHBondContact O-N 3.42Å; I504-P520 VanDerWaalsContact O-CD 3.28Å; I504-P520 WeakPolarHBondContact O-CD 3.04Å; I504-P520 WeakPolarHBondContact O-CG 3.4Å
505A97.5Very high91.5Very high0 Ų023.5 Ų23.50%012%0.124CC..EExtended strand (participates in β ladder)trans-128.6158.5164.300000111.7I444 C470 V471 V472 P520 V546I444-A505 HydrophobicContact CB-CB 3.88Å; I444-A505 HydrophobicContact CG1-CB 4.05Å; I444-A505 HydrophobicContact CG2-CB 3.88Å; C470-A505 PolarHBondContact O-N 3.25Å; V471-A505 CarbonylContact C-O 3.58Å; V471-A505 WeakPolarHBondContact CA-O 3.38Å; V471-A505 HydrophobicContact CG1-CB 4.42Å; V471-A505 HydrophobicContact CG2-CB 4.31Å; V472-A505 PolarHBondContact N-O 3.22Å; A505-P520 CarbonylContact C-O 3.52Å; A505-P520 VanDerWaalsContact CA-O 3.29Å; A505-P520 WeakPolarHBondContact CA-O 3.13Å; A505-P520 HydrophobicContact CB-CG 4.02Å; A505-V546 HydrophobicContact CB-CB 4.31Å; A505-V546 HydrophobicContact CB-CG2 4.09Å
506L97.9Very high90.3Very high0 Ų023.9 Ų23.90%013%0.126CC..EExtended strand (participates in β ladder)trans-111135.8170.6175.768.4000110V472 V474 L490 M491 L494 T508 L512 P520 S521 A522V472-L506 HydrophobicContact CB-CD1 4.48Å; V472-L506 HydrophobicContact CG1-CD1 4.2Å; V472-L506 CarbonylContact O-C 3.55Å; V472-L506 WeakPolarHBondContact O-CA 3.42Å; V472-L506 WeakPolarHBondContact O-CD1 3.43Å; V474-L506 HydrophobicContact CG2-CD1 3.98Å; L490-L506 HydrophobicContact CD1-CD1 3.79Å; L490-L506 HydrophobicContact CD1-CD2 3.92Å; M491-L506 HydrophobicContact CE-CD2 3.96Å; L494-L506 HydrophobicContact CD1-CB 4.33Å; L506-T508 HydrophobicContact CD2-CG2 4.22Å; L506-T508 HydrophobicContact CG-CG2 4.31Å; L506-L512 HydrophobicContact CD2-CD1 3.77Å; L506-L512 HydrophobicContact CD2-CD2 3.88Å; L506-L512 HydrophobicContact CD2-CG 4.05Å; L506-P520 PolarHBondContact N-O 2.93Å; L506-S521 CarbonylContact O-C 3.59Å; L506-S521 WeakPolarHBondContact O-CA 3.45Å; L506-A522 PolarHBondContact O-N 2.9Å
507V98.4Very high89.4Confident0 Ų024.8 Ų24.80%014%0.137CC..EExtended strand (participates in β ladder)trans-126.4125.3167.9-178.80000108.9V471 V472 V473 V474 A522 V525 L535 I544 V546 L553V471-V507 HydrophobicContact CG1-CB 4.27Å; V471-V507 HydrophobicContact CG1-CG2 3.49Å; V471-V507 VanDerWaalsContact CG1-CG2 3.49Å; V472-V507 PolarHBondContact O-N 3.04Å; V473-V507 WeakPolarHBondContact CA-O 3.27Å; V473-V507 HydrophobicContact CG2-CB 4.36Å; V474-V507 PolarHBondContact N-O 3.41Å; V507-A522 WeakPolarHBondContact CA-O 3.3Å; V507-A522 HydrophobicContact CG2-CB 4.17Å; V507-V525 HydrophobicContact CG1-CG2 3.83Å; V507-L535 HydrophobicContact CG1-CD1 3.81Å; V507-I544 HydrophobicContact CG2-CG2 4.31Å; V507-V546 HydrophobicContact CG2-CG2 3.66Å; V507-L553 HydrophobicContact CG1-CD1 4.46Å; V507-L553 HydrophobicContact CG2-CD1 4.12Å
508T98.4Very high88.9Confident0 Ų027.9 Ų27.90%015%0.15CC..EExtended strand (participates in β ladder)trans-152.5144.7179.7-176.90000112.1V474 L487 L506 G510 A522 I523 H524 V525V474-T508 VanDerWaalsContact O-CA 3.28Å; V474-T508 WeakPolarHBondContact O-CA 3.29Å; V474-T508 WeakPolarHBondContact O-CB 3.25Å; V474-T508 PolarHBondContact O-OG1 3.35Å; L487-T508 HydrophobicContact CD1-CG2 4.15Å; L487-T508 WeakPolarHBondContact CD1-OG1 3.24Å; L506-T508 HydrophobicContact CD2-CG2 4.22Å; L506-T508 HydrophobicContact CG-CG2 4.31Å; T508-G510 PolarHBondContact OG1-N 2.93Å; T508-A522 PolarHBondContact N-O 2.63Å; T508-I523 HydrophobicContact CG2-CB 4.29Å; T508-I523 HydrophobicContact CG2-CG2 3.89Å; T508-I523 CarbonylContact O-C 3.57Å; T508-I523 WeakPolarHBondContact O-CA 3.47Å; T508-H524 PolarHBondContact O-N 3.48Å; T508-V525 VanDerWaalsContact O-CG2 3.28Å; T508-V525 WeakPolarHBondContact O-CG2 3.31Å; T508-V525 PolarHBondContact O-N 3.29Å; T508-V525 VanDerWaalsContact O-N 3.11Å
509D98.3Very high88.9Confident1 Ų127.4 Ų27.41%0.00515%0.148CC..SBendtrans-76.8-9.6166.551.81.4000112.6R475 H476 Q477 G478 V525 E528 A529 L535R475-D509 WeakPolarHBondContact CA-OD1 3.25Å; H476-D509 PolarHBondContact N-OD1 2.86Å; H476-D509 VanDerWaalsContact N-OD1 3.13Å; H476-D509 PolarHBondContact N-OD2 3.48Å; Q477-D509 WeakPolarHBondContact CA-OD1 3.36Å; Q477-D509 PolarHBondContact N-OD1 3.35Å; G478-D509 WeakPolarHBondContact CA-O 3.29Å; D509-V525 HydrophobicContact CB-CB 4.36Å; D509-V525 WeakPolarHBondContact CB-O 3.14Å; D509-E528 HydrophobicContact CB-CB 3.78Å; D509-A529 VanDerWaalsContact OD2-CB 3.3Å; D509-A529 WeakPolarHBondContact OD2-CB 3.24Å; D509-A529 PolarHBondContact OD2-N 3.45Å; D509-L535 HydrophobicContact CB-CD2 3.79Å
510G97Very high89Confident0 Ų023 Ų230%013%0.125CC..SBendtrans-83.9-158.4168.900000113.2Q477 T508 H524Q477-G510 WeakPolarHBondContact O-CA 3.39Å; Q477-G510 PolarHBondContact O-N 3.09Å; T508-G510 PolarHBondContact OG1-N 2.93Å; G510-H524 PolarHBondContact O-CD2 2.99Å; G510-H524 PolarHBondContact O-N 3.48Å
511R95.3Very high89.1Confident0 Ų018.4 Ų18.40%011%0.109CC..BIsolated β-bridgetrans-135.7169-176.960.4165171.7-160.10.9112.4S125 K156 N302 M484 P485 E486 L487 H524S125-R511 PolarHBondContact OG-NH2 2.67Å; K156-R511 VanDerWaalsContact CE-CZ 3.43Å; N302-R511 WeakPolarHBondContact OD1-CD 3.48Å; M484-R511 HydrophobicContact CE-CB 4Å; M484-R511 HydrophobicContact CE-CG 3.83Å; M484-R511 HydrophobicContact CG-CG 4.33Å; M484-R511 PolarHBondContact O-NE 2.91Å; M484-R511 PolarHBondContact O-NH2 3.46Å; P485-R511 VanDerWaalsContact O-CG 3.3Å; P485-R511 WeakPolarHBondContact O-CG 3.34Å; E486-R511 WeakPolarHBondContact CA-O 3.4Å; E486-R511 HydrophobicContact CG-CG 3.88Å; L487-R511 PolarHBondContact N-O 2.93Å; R511-H524 WeakPolarHBondContact CB-NE2 3.25Å
512L91.1Very high89.3Confident1 Ų113 Ų131%0.0057%0.072CC..  trans-121.7164.1169.1-60.4173.4000110.3L487 M491 L506 S516 I523L487-L512 HydrophobicContact CB-CD2 4.08Å; M491-L512 HydrophobicContact CE-CD1 3.61Å; M491-L512 HydrophobicContact CE-CD2 3.7Å; M491-L512 HydrophobicContact CE-CG 4.31Å; M491-L512 HydrophobicContact CG-CD2 4.49Å; M491-L512 HydrophobicContact SD-CD1 3.76Å; M491-L512 HydrophobicContact SD-CD2 4.31Å; L506-L512 HydrophobicContact CD2-CD1 3.77Å; L506-L512 HydrophobicContact CD2-CD2 3.88Å; L506-L512 HydrophobicContact CD2-CG 4.05Å; L512-S516 WeakPolarHBondContact CB-OG 3.46Å; L512-S516 WeakPolarHBondContact CD1-OG 3.26Å; L512-I523 HydrophobicContact CD1-CG2 4.04Å; L512-I523 HydrophobicContact CG-CG2 3.96Å
513S76.4Confident89.3Confident8 Ų810.9 Ų10.96%0.0566%0.063CC..  trans-62.5156.4173.475.90000111.8E486 A515 S516E486-S513 VanDerWaalsContact CD-CA 3.48Å; E486-S513 VanDerWaalsContact OE2-CA 3.26Å; E486-S513 WeakPolarHBondContact OE2-CA 3.39Å; E486-S513 WeakPolarHBondContact OE2-CB 3.47Å; S513-A515 PolarHBondContact O-N 3.33Å; S513-A515 PolarHBondContact OG-N 2.71Å; S513-S516 WeakPolarHBondContact O-CB 3.47Å; S513-S516 PolarHBondContact O-N 3.42Å; S513-S516 PolarHBondContact O-OG 3.19Å
514G66.4Low89.3Confident2 Ų27.3 Ų7.32%0.0215%0.047CC..THydrogen-bonded Turntrans-57.2-15.8171.500000114.8S300 P338 K433 S516S300-G514 VanDerWaalsContact OG-CA 3.27Å; S300-G514 WeakPolarHBondContact OG-CA 3.49Å; P338-G514 WeakPolarHBondContact CG-O 3.3Å; K433-G514 PolarHBondContact NZ-O 2.91Å; G514-S516 VanDerWaalsContact C-N 3.28Å; G514-S516 PolarHBondContact O-N 2.99Å
515A60.9Low89.4Confident18 Ų187.3 Ų7.315%0.1495%0.047CC..THydrogen-bonded Turntrans-82.15.5176.600000114.7F223 P338 S513 G517F223-A515 HydrophobicContact CD2-CB 3.88Å; F223-A515 HydrophobicContact CE2-CB 3.7Å; P338-A515 WeakPolarHBondContact CB-O 3.41Å; S513-A515 PolarHBondContact O-N 3.33Å; S513-A515 PolarHBondContact OG-N 2.71Å; A515-G517 PolarHBondContact O-N 3.4Å
516S66.4Low89.4Confident12 Ų128.2 Ų8.28%0.0845%0.053CC..  trans-62.1120.8-179.4-54.20000110.9L512 S513 G514L512-S516 WeakPolarHBondContact CB-OG 3.46Å; L512-S516 WeakPolarHBondContact CD1-OG 3.26Å; S513-S516 WeakPolarHBondContact O-CB 3.47Å; S513-S516 PolarHBondContact O-N 3.42Å; S513-S516 PolarHBondContact O-OG 3.19Å; G514-S516 VanDerWaalsContact C-N 3.28Å; G514-S516 PolarHBondContact O-N 2.99Å
517G73.6Confident89.4Confident25 Ų2511.5 Ų11.526%0.2587%0.074SC..  trans-96.7-130.3-167.200000113.9A515 V519A515-G517 PolarHBondContact O-N 3.4Å; G517-V519 PolarHBondContact O-N 3.14Å
518K86.7Confident89.4Confident64 Ų6411.7 Ų11.728%0.2788%0.075SC..SBendtrans-65.5-5-171.166.2-177.2-178.2-166.50117.1A436 G495 L498 D499A436-K518 VanDerWaalsContact O-CA 3.29Å; A436-K518 WeakPolarHBondContact O-CA 3.33Å; G495-K518 WeakPolarHBondContact O-CE 3.47Å; G495-K518 PolarHBondContact O-NZ 3.27Å; L498-K518 HydrophobicContact CD1-CD 4.42Å; L498-K518 HydrophobicContact CD1-CG 3.9Å; D499-K518 IonicContact OD1-NZ 3.74Å; D499-K518 PolarHBondContact OD1-NZ 2.89Å; D499-K518 IonicContact OD2-NZ 3.46Å; D499-K518 PolarHBondContact OD2-NZ 3.34Å
519V91.8Very high89.4Confident8 Ų811.9 Ų11.95%0.0488%0.077CC..SBendtrans-85.1117.6-177.8-177.70000109.7L494 L498 G517 S521L494-V519 HydrophobicContact CB-CG1 4.25Å; L494-V519 HydrophobicContact CB-CG2 3.94Å; L494-V519 HydrophobicContact CD1-CG1 4.22Å; L498-V519 HydrophobicContact CD1-CB 4.13Å; L498-V519 HydrophobicContact CD1-CG2 3.56Å; G517-V519 PolarHBondContact O-N 3.14Å; V519-S521 PolarHBondContact O-N 3.11Å; V519-S521 VanDerWaalsContact O-N 3.14Å; V519-S521 PolarHBondContact O-OG 2.71Å
520P94.5Very high89.3Confident0 Ų017 Ų170%010%0.097CC..  trans-62.5118.6174.627.1-33.6000109.6M432 V437 N441 I444 I504 A505 L506M432-P520 HydrophobicContact CE-CB 3.45Å; M432-P520 VanDerWaalsContact CE-CB 3.45Å; M432-P520 HydrophobicContact SD-CB 4.45Å; V437-P520 HydrophobicContact CG1-CB 4.05Å; N441-P520 WeakPolarHBondContact O-CB 3.15Å; N441-P520 VanDerWaalsContact O-CG 3.25Å; N441-P520 WeakPolarHBondContact O-CG 3.15Å; I444-P520 HydrophobicContact CD1-CG 4.49Å; I444-P520 HydrophobicContact CG1-CG 3.76Å; I504-P520 VanDerWaalsContact O-CD 3.28Å; I504-P520 WeakPolarHBondContact O-CD 3.04Å; I504-P520 WeakPolarHBondContact O-CG 3.4Å; A505-P520 CarbonylContact C-O 3.52Å; A505-P520 VanDerWaalsContact CA-O 3.29Å; A505-P520 WeakPolarHBondContact CA-O 3.13Å; A505-P520 HydrophobicContact CB-CG 4.02Å; L506-P520 PolarHBondContact N-O 2.93Å
521S96Very high89.2Confident9 Ų920.6 Ų20.66%0.06312%0.116CC..EExtended strand (participates in β ladder)trans-132.9113.3-170.9-55.50000110.4M432 L506 V519M432-S521 WeakPolarHBondContact CA-O 3.39Å; M432-S521 WeakPolarHBondContact CB-O 3.45Å; M432-S521 WeakPolarHBondContact CG-O 3.48Å; L506-S521 CarbonylContact O-C 3.59Å; L506-S521 WeakPolarHBondContact O-CA 3.45Å; V519-S521 PolarHBondContact O-N 3.11Å; V519-S521 VanDerWaalsContact O-N 3.14Å; V519-S521 PolarHBondContact O-OG 2.71Å
522A97.1Very high89.2Confident0 Ų023.1 Ų23.10%014%0.142CC..EExtended strand (participates in β ladder)trans-85.1101.9165.800000108.3L423 A430 L506 V507 T508 V546 L553L423-A522 HydrophobicContact CD1-CB 3.49Å; L423-A522 VanDerWaalsContact CD1-CB 3.49Å; A430-A522 HydrophobicContact CB-CB 4.3Å; L506-A522 PolarHBondContact O-N 2.9Å; V507-A522 WeakPolarHBondContact CA-O 3.3Å; V507-A522 HydrophobicContact CG2-CB 4.17Å; T508-A522 PolarHBondContact N-O 2.63Å; A522-V546 HydrophobicContact CB-CG1 4.25Å; A522-L553 HydrophobicContact CB-CD1 3.93Å; A522-L553 HydrophobicContact CB-CD2 4.19Å
523I97.1Very high89.5Confident5 Ų523.3 Ų23.33%0.02614%0.144CC..EExtended strand (participates in β ladder)trans-111.6167.9-177.464.3171.9000110.4T301 A430 V431 T508 L512 V525T301-I523 HydrophobicContact CG2-CD1 4.26Å; T301-I523 VanDerWaalsContact OG1-CD1 3.24Å; T301-I523 WeakPolarHBondContact OG1-CD1 3.49Å; A430-I523 WeakPolarHBondContact CB-O 3.33Å; V431-I523 HydrophobicContact CG2-CD1 4.31Å; V431-I523 HydrophobicContact CG2-CG1 3.79Å; V431-I523 PolarHBondContact N-O 3Å; V431-I523 WeakPolarHBondContact O-CG1 3.46Å; V431-I523 PolarHBondContact O-N 2.84Å; T508-I523 HydrophobicContact CG2-CB 4.29Å; T508-I523 HydrophobicContact CG2-CG2 3.89Å; T508-I523 CarbonylContact O-C 3.57Å; T508-I523 WeakPolarHBondContact O-CA 3.47Å; L512-I523 HydrophobicContact CD1-CG2 4.04Å; L512-I523 HydrophobicContact CG-CG2 3.96Å; I523-V525 PolarHBondContact O-N 2.95Å
524H97.8Very high90.6Very high0 Ų024.8 Ų24.80%015%0.151CC..EExtended strand (participates in β ladder)trans61.925.2-179.2-51.5169.8000113M305 W320 V431 T508 G510 R511 T526 A594M305-H524 WeakPolarHBondContact CE-CE1 3.4Å; M305-H524 WeakPolarHBondContact CE-NE2 3.39Å; W320-H524 HydrophobicContact CH2-CB 3.83Å; W320-H524 WeakPolarHBondContact CH2-O 3.41Å; W320-H524 HydrophobicContact CZ2-CB 3.96Å; V431-H524 HydrophobicContact CG2-CB 4.26Å; V431-H524 WeakPolarHBondContact CG2-ND1 3.43Å; T508-H524 PolarHBondContact O-N 3.48Å; G510-H524 PolarHBondContact O-CD2 2.99Å; G510-H524 PolarHBondContact O-N 3.48Å; R511-H524 WeakPolarHBondContact CB-NE2 3.25Å; H524-T526 PolarHBondContact O-N 3.44Å; H524-T526 PolarHBondContact O-OG1 2.73Å; H524-A594 HydrophobicContact CB-CB 3.66Å
525V98.6Very high92.1Very high0 Ų024.7 Ų24.70%015%0.15CC..EExtended strand (participates in β ladder)trans-50.2118.7-179.4176.50000109.7R429 A430 V507 T508 D509 I523 L535 L553R429-V525 CarbonylContact O-C 3.55Å; R429-V525 WeakPolarHBondContact O-CA 3.29Å; A430-V525 HydrophobicContact CB-CG2 3.89Å; V507-V525 HydrophobicContact CG1-CG2 3.83Å; T508-V525 VanDerWaalsContact O-CG2 3.28Å; T508-V525 WeakPolarHBondContact O-CG2 3.31Å; T508-V525 PolarHBondContact O-N 3.29Å; T508-V525 VanDerWaalsContact O-N 3.11Å; D509-V525 HydrophobicContact CB-CB 4.36Å; D509-V525 WeakPolarHBondContact CB-O 3.14Å; I523-V525 PolarHBondContact O-N 2.95Å; V525-L535 HydrophobicContact CB-CD2 4.32Å; V525-L535 HydrophobicContact CG1-CB 4.46Å; V525-L535 HydrophobicContact CG1-CD2 4.27Å; V525-L553 HydrophobicContact CG2-CD2 4.06Å
526T98.3Very high93.9Very high19 Ų1923.9 Ų23.912%0.11714%0.144CC..EExtended strand (participates in β ladder)trans-129.2130.9-174.7-61.40000109.1R429 H524 A594R429-T526 PolarHBondContact N-O 2.87Å; R429-T526 PolarHBondContact O-N 2.86Å; H524-T526 PolarHBondContact O-N 3.44Å; H524-T526 PolarHBondContact O-OG1 2.73Å; T526-A594 PolarHBondContact OG1-N 2.84Å
527P98.1Very high95.4Very high69 Ų6925.6 Ų25.645%0.44815%0.149SC..SBendcis-63.4144.10.3-19.532.8000113.3
528E98.2Very high96.6Very high5 Ų524.4 Ų24.42%0.02314%0.137CC..  trans-65.6159.1175.766.1177.410100110.8G478 P479 K480 A481 D509 Y530 D531 G533G478-E528 WeakPolarHBondContact CA-OE2 3.37Å; P479-E528 VanDerWaalsContact CD-OE1 3.23Å; P479-E528 WeakPolarHBondContact CD-OE1 3.49Å; K480-E528 WeakPolarHBondContact CB-OE1 3.22Å; K480-E528 PolarHBondContact N-OE1 3.04Å; K480-E528 PolarHBondContact N-OE2 3.26Å; A481-E528 VanDerWaalsContact CB-OE2 3.31Å; A481-E528 WeakPolarHBondContact CB-OE2 3.33Å; A481-E528 PolarHBondContact N-OE2 2.87Å; D509-E528 HydrophobicContact CB-CB 3.78Å; E528-Y530 PolarHBondContact O-N 2.9Å; E528-Y530 WeakPolarHBondContact OE2-CB 3.47Å; E528-D531 HydrophobicContact CG-CB 4.01Å; E528-D531 PolarHBondContact O-N 3.39Å; E528-D531 VanDerWaalsContact O-N 3.17Å; E528-G533 PolarHBondContact O-N 3.15Å
529A98.1Very high97.2Very high4 Ų427.5 Ų27.53%0.03315%0.147CC..G310 helixtrans-59.5-36.7-179.100000111.9R475 H476 D509 D531 G532 L535 A536R475-A529 HydrophobicContact CB-CB 3.97Å; H476-A529 WeakPolarHBondContact NE2-CB 3.5Å; D509-A529 VanDerWaalsContact OD2-CB 3.3Å; D509-A529 WeakPolarHBondContact OD2-CB 3.24Å; D509-A529 PolarHBondContact OD2-N 3.45Å; A529-D531 VanDerWaalsContact C-N 3.32Å; A529-D531 PolarHBondContact O-N 3.35Å; A529-G532 PolarHBondContact O-N 3.47Å; A529-L535 HydrophobicContact CB-CB 4.25Å; A529-L535 HydrophobicContact CB-CD2 4.48Å; A529-A536 HydrophobicContact CB-CB 3.93Å
530Y96.7Very high97.5Very high107 Ų10732.2 Ų32.242%0.4217%0.172SC..G310 helixtrans-63.8-32.8179.2-176.5-99000113.8K480 A481 E528 G532 L572K480-Y530 HydrophobicContact CB-CD1 3.65Å; K480-Y530 HydrophobicContact CB-CE1 3.94Å; A481-Y530 HydrophobicContact CB-CG 4.27Å; E528-Y530 PolarHBondContact O-N 2.9Å; E528-Y530 WeakPolarHBondContact OE2-CB 3.47Å; Y530-G532 PolarHBondContact O-N 2.93Å; Y530-L572 HydrophobicContact CD2-CD1 3.55Å; Y530-L572 HydrophobicContact CE2-CD1 3.73Å
531D95.4Very high97.6Very high77 Ų7734.6 Ų34.641%0.41220%0.197SC..G310 helixtrans-84.611175.3-87.9-17.6000112.3K480 E528 A529K480-D531 VanDerWaalsContact CD-OD1 3.31Å; K480-D531 WeakPolarHBondContact CD-OD1 2.97Å; K480-D531 WeakPolarHBondContact CE-OD2 3.24Å; K480-D531 IonicContact NZ-OD1 3.7Å; K480-D531 PolarHBondContact NZ-OD1 2.93Å; K480-D531 IonicContact NZ-OD2 2.75Å; K480-D531 PolarHBondContact NZ-OD2 3.48Å; E528-D531 HydrophobicContact CG-CB 4.01Å; E528-D531 PolarHBondContact O-N 3.39Å; E528-D531 VanDerWaalsContact O-N 3.17Å; A529-D531 VanDerWaalsContact C-N 3.32Å; A529-D531 PolarHBondContact O-N 3.35Å
532G95Very high97.8Very high53 Ų5335 Ų3555%0.54620%0.198SC..THydrogen-bonded Turntrans84.417.7179.600000114.4A529 Y530A529-G532 PolarHBondContact O-N 3.47Å; Y530-G532 PolarHBondContact O-N 2.93Å
533G97.5Very high97.9Very high4 Ų437.7 Ų37.74%0.04121%0.212CC..  trans-58.2153.2171.700000112.3E528 L535 A536E528-G533 PolarHBondContact O-N 3.15Å; G533-L535 PolarHBondContact O-N 3.46Å; G533-A536 WeakPolarHBondContact O-CB 3.48Å; G533-A536 PolarHBondContact O-N 2.88Å
534L98.3Very high97.9Very high39 Ų3937.4 Ų37.420%0.20421%0.211CC..G310 helixtrans-58.6-22.9-175.6-169.566.9000112.9N426 L427 A536 K537 L555 L562N426-L534 HydrophobicContact CB-CD2 4.01Å; N426-L534 WeakPolarHBondContact O-CD2 3.34Å; L427-L534 HydrophobicContact CD2-CB 4.31Å; L427-L534 HydrophobicContact CD2-CD2 4.29Å; L427-L534 HydrophobicContact CD2-CG 4.28Å; L534-A536 PolarHBondContact O-N 3.36Å; L534-A536 VanDerWaalsContact O-N 3.13Å; L534-K537 HydrophobicContact CD1-CB 4.28Å; L534-K537 HydrophobicContact CD1-CD 4.06Å; L534-K537 HydrophobicContact CD1-CG 4.45Å; L534-K537 PolarHBondContact O-N 3.29Å; L534-L555 HydrophobicContact CD2-CD2 4.18Å; L534-L555 HydrophobicContact CG-CD2 4.27Å; L534-L562 HydrophobicContact CD1-CD1 4.34Å; L534-L562 HydrophobicContact CD1-CD2 4.3Å; L534-L562 HydrophobicContact CD2-CD1 4.12Å
535L98.3Very high98Very high0 Ų040.6 Ų40.60%022%0.223CC..G310 helixtrans-52.9-30.7172.5-164.668000113L427 V473 R475 V507 D509 V525 A529 G533 K537 V538L427-L535 HydrophobicContact CD2-CD1 4.44Å; V473-L535 HydrophobicContact CG1-CD1 3.7Å; V473-L535 HydrophobicContact CG1-CG 4.38Å; R475-L535 HydrophobicContact CB-CD2 3.89Å; R475-L535 HydrophobicContact CB-CG 3.95Å; V507-L535 HydrophobicContact CG1-CD1 3.81Å; D509-L535 HydrophobicContact CB-CD2 3.79Å; V525-L535 HydrophobicContact CB-CD2 4.32Å; V525-L535 HydrophobicContact CG1-CB 4.46Å; V525-L535 HydrophobicContact CG1-CD2 4.27Å; A529-L535 HydrophobicContact CB-CB 4.25Å; A529-L535 HydrophobicContact CB-CD2 4.48Å; G533-L535 PolarHBondContact O-N 3.46Å; L535-K537 PolarHBondContact O-N 2.71Å; L535-V538 HydrophobicContact CD1-CG2 4.34Å; L535-V538 PolarHBondContact O-N 3.29Å
536A98.3Very high98Very high2 Ų240.6 Ų40.62%0.01722%0.223CC..G310 helixtrans-68-18.4175.400000113.9R475 A529 G533 L534 P567 H568R475-A536 PolarHBondContact NH1-O 2.83Å; A529-A536 HydrophobicContact CB-CB 3.93Å; G533-A536 WeakPolarHBondContact O-CB 3.48Å; G533-A536 PolarHBondContact O-N 2.88Å; L534-A536 PolarHBondContact O-N 3.36Å; L534-A536 VanDerWaalsContact O-N 3.13Å; A536-P567 HydrophobicContact CB-CB 3.71Å; A536-H568 PolarHBondContact O-N 3.07Å
537K98.5Very high97.9Very high47 Ų4740.5 Ų40.520%0.20422%0.222CC..G310 helixtrans-98.6-5.1-178.9-61.7-165.8-179.1-157.70114.1L534 L535 L562 R565 P567L534-K537 HydrophobicContact CD1-CB 4.28Å; L534-K537 HydrophobicContact CD1-CD 4.06Å; L534-K537 HydrophobicContact CD1-CG 4.45Å; L534-K537 PolarHBondContact O-N 3.29Å; L535-K537 PolarHBondContact O-N 2.71Å; K537-L562 WeakPolarHBondContact CD-O 3.34Å; K537-L562 PolarHBondContact NZ-O 3.23Å; K537-R565 HydrophobicContact CB-CB 4.38Å; K537-R565 HydrophobicContact CD-CB 4.11Å; K537-R565 WeakPolarHBondContact CD-O 3.41Å; K537-R565 WeakPolarHBondContact CE-O 3.42Å; K537-R565 PolarHBondContact NZ-O 2.99Å; K537-R565 PolarHBondContact O-NH1 3.29Å; K537-P567 HydrophobicContact CG-CB 4.23Å
538V98.6Very high97.8Very high1 Ų137.4 Ų37.41%0.00620%0.202CC..  trans-64.2138.5176.1-178.20000109.7L427 A448 V450 V473 R475 L535 I544 L555L427-V538 HydrophobicContact CD2-CG2 3.91Å; A448-V538 HydrophobicContact CB-CG1 3.84Å; V450-V538 HydrophobicContact CG2-CB 4.49Å; V450-V538 HydrophobicContact CG2-CG1 3.8Å; V473-V538 HydrophobicContact CG2-CG1 4.27Å; R475-V538 PolarHBondContact NH1-O 3.39Å; L535-V538 HydrophobicContact CD1-CG2 4.34Å; L535-V538 PolarHBondContact O-N 3.29Å; V538-I544 HydrophobicContact CG1-CD1 3.96Å; V538-L555 HydrophobicContact CG1-CD1 4.47Å; V538-L555 HydrophobicContact CG2-CD1 4.23Å; V538-L555 HydrophobicContact CG2-CD2 3.99Å
539R98.3Very high97.5Very high129 Ų12942 Ų4249%0.48722%0.224SC..  trans-125.7156.9177.3-65177.6177.8173.7-4109.9G541 D542R539-G541 PolarHBondContact O-N 3.45Å; R539-D542 PolarHBondContact N-OD2 3.3Å; R539-D542 WeakPolarHBondContact O-CB 3.45Å; R539-D542 VanDerWaalsContact O-CG 3.28Å; R539-D542 PolarHBondContact O-N 3.16Å
540D98.3Very high97.3Very high106 Ų10646.2 Ų46.257%0.56725%0.249SC*.THydrogen-bonded Turntrans-55135.9172.8-68-59.5000111.2A448 V449 V450 D542A448-D540 WeakPolarHBondContact O-CA 3.41Å; V449-D540 WeakPolarHBondContact CA-OD1 3.48Å; V450-D540 PolarHBondContact N-OD1 3.49Å; D540-D542 VanDerWaalsContact C-N 3.34Å
541G98.3Very high97.2Very high50 Ų5041.6 Ų41.652%0.51523%0.234SC..THydrogen-bonded Turntrans89.6-15.2179.900000115.4A448 R539 I543A448-G541 PolarHBondContact O-N 3.44Å; R539-G541 PolarHBondContact O-N 3.45Å; G541-I543 PolarHBondContact O-N 3.42Å
542D98.7Very high97.4Very high17 Ų1740.5 Ų40.59%0.09123%0.226CC..  trans-59.8138174.7-69.5-22.6000110.9P447 A448 R539 D540 I544 L555 V557 R565P447-D542 CarbonylContact C-O 3.58Å; P447-D542 WeakPolarHBondContact CA-O 3.17Å; A448-D542 HydrophobicContact CB-CB 4.36Å; A448-D542 WeakPolarHBondContact CB-O 3.19Å; A448-D542 PolarHBondContact N-O 3.37Å; R539-D542 PolarHBondContact N-OD2 3.3Å; R539-D542 WeakPolarHBondContact O-CB 3.45Å; R539-D542 VanDerWaalsContact O-CG 3.28Å; R539-D542 PolarHBondContact O-N 3.16Å; D540-D542 VanDerWaalsContact C-N 3.34Å; D542-I544 PolarHBondContact O-N 2.91Å; D542-L555 HydrophobicContact CB-CD1 3.63Å; D542-V557 HydrophobicContact CB-CG2 4.11Å; D542-R565 IonicContact OD1-CZ 3.47Å; D542-R565 IonicContact OD1-NH1 3.4Å; D542-R565 PolarHBondContact OD1-NH1 3.26Å; D542-R565 IonicContact OD1-NH2 2.73Å; D542-R565 PolarHBondContact OD1-NH2 3.28Å; D542-R565 IonicContact OD2-CZ 3.6Å; D542-R565 IonicContact OD2-NH1 3.15Å; D542-R565 PolarHBondContact OD2-NH1 3.48Å; D542-R565 IonicContact OD2-NH2 3.85Å
543I98.8Very high97.5Very high57 Ų5738 Ų3829%0.29220%0.2SC..EExtended strand (participates in β ladder)trans-79.2126.2176.2-56.4-54.8000109.5E445 P447 G541 L556E445-I543 HydrophobicContact CG-CG2 3.51Å; P447-I543 HydrophobicContact CB-CD1 4.23Å; P447-I543 HydrophobicContact CG-CD1 3.85Å; G541-I543 PolarHBondContact O-N 3.42Å; I543-L556 HydrophobicContact CB-CB 4.06Å; I543-L556 HydrophobicContact CG2-CB 4.23Å; I543-L556 HydrophobicContact CG2-CD1 4.36Å; I543-L556 HydrophobicContact CG2-CD2 3.99Å; I543-L556 HydrophobicContact CG2-CG 4.44Å; I543-L556 PolarHBondContact O-N 2.84Å
544I98.8Very high97.6Very high0 Ų039 Ų390%021%0.206CC..EExtended strand (participates in β ladder)trans-117.7132.7173.2-62.2174.9000108.9L427 E445 A446 A448 V471 V473 V507 V538 D542 V546 T554 L555L427-I544 HydrophobicContact CD1-CG2 4.06Å; E445-I544 VanDerWaalsContact CA-O 3.32Å; E445-I544 WeakPolarHBondContact CA-O 3.32Å; A446-I544 PolarHBondContact N-O 3.4Å; A446-I544 VanDerWaalsContact N-O 3.15Å; A446-I544 PolarHBondContact O-N 3.35Å; A448-I544 HydrophobicContact CB-CD1 3.81Å; A448-I544 HydrophobicContact CB-CG1 4.34Å; V471-I544 HydrophobicContact CB-CB 4.16Å; V471-I544 HydrophobicContact CB-CD1 4.5Å; V471-I544 HydrophobicContact CG1-CB 4.15Å; V471-I544 HydrophobicContact CG1-CD1 4.14Å; V471-I544 HydrophobicContact CG1-CG2 4.1Å; V471-I544 HydrophobicContact CG2-CB 4.01Å; V471-I544 HydrophobicContact CG2-CG2 4.4Å; V473-I544 HydrophobicContact CG2-CD1 3.55Å; V507-I544 HydrophobicContact CG2-CG2 4.31Å; V538-I544 HydrophobicContact CG1-CD1 3.96Å; D542-I544 PolarHBondContact O-N 2.91Å; I544-V546 HydrophobicContact CG2-CG2 4.07Å; I544-T554 CarbonylContact C-O 3.57Å; I544-T554 WeakPolarHBondContact CA-O 3.4Å; I544-L555 HydrophobicContact CD1-CD1 4.34Å; I544-L555 HydrophobicContact CG1-CD1 3.72Å
545R98.7Very high97.6Very high66 Ų6637.3 Ų37.325%0.24920%0.197CC..EExtended strand (participates in β ladder)trans-102.5120.1169.7-175.9-174.8-62.1136.90.4110.2I444 E445 N547 E552 L553 T554 L556I444-R545 CarbonylContact O-C 3.59Å; I444-R545 WeakPolarHBondContact O-CA 3.48Å; E445-R545 HydrophobicContact CB-CB 4.48Å; E445-R545 HydrophobicContact CG-CB 4.33Å; E445-R545 IonicContact OE2-CZ 3.83Å; E445-R545 IonicContact OE2-NE 2.81Å; E445-R545 PolarHBondContact OE2-NE 3.41Å; E445-R545 IonicContact OE2-NH2 3.37Å; E445-R545 PolarHBondContact OE2-NH2 3.5Å; R545-N547 HydrophobicContact CG-CB 4.46Å; R545-E552 VanDerWaalsContact CD-OE2 3.31Å; R545-E552 WeakPolarHBondContact CD-OE2 3.3Å; R545-E552 IonicContact CZ-OE1 3.89Å; R545-E552 IonicContact NH1-OE1 2.71Å; R545-E552 PolarHBondContact NH1-OE1 3.05Å; R545-E552 IonicContact NH1-OE2 2.73Å; R545-L553 WeakPolarHBondContact O-CA 3.31Å; R545-T554 PolarHBondContact N-O 2.83Å; R545-T554 PolarHBondContact O-N 2.68Å; R545-L556 HydrophobicContact CB-CD1 3.68Å
546V98.5Very high97.6Very high0 Ų040.3 Ų40.30%021%0.213CC..EExtended strand (participates in β ladder)trans-111.6107.7169.6-1750000107.5L423 M432 V443 I444 V471 A505 V507 A522 I544 L553L423-V546 HydrophobicContact CD1-CG1 4.09Å; M432-V546 HydrophobicContact SD-CG1 4.28Å; V443-V546 WeakPolarHBondContact CA-O 3.41Å; I444-V546 PolarHBondContact N-O 2.82Å; I444-V546 PolarHBondContact O-N 3.06Å; V471-V546 HydrophobicContact CG1-CG2 4.41Å; A505-V546 HydrophobicContact CB-CB 4.31Å; A505-V546 HydrophobicContact CB-CG2 4.09Å; V507-V546 HydrophobicContact CG2-CG2 3.66Å; A522-V546 HydrophobicContact CB-CG1 4.25Å; I544-V546 HydrophobicContact CG2-CG2 4.07Å; V546-L553 HydrophobicContact CG2-CD1 3.92Å
547N97.6Very high97.6Very high18 Ų1841.2 Ų41.210%0.09622%0.218CC..EExtended strand (participates in β ladder)trans-118.293.2-177.5-168.1-27.7000110.8V443 R545 Q549 T550 G551 E552V443-N547 HydrophobicContact CG1-CB 4.37Å; V443-N547 WeakPolarHBondContact CG2-OD1 3.2Å; R545-N547 HydrophobicContact CG-CB 4.46Å; N547-Q549 PolarHBondContact O-N 3Å; N547-Q549 WeakPolarHBondContact OD1-CA 3.46Å; N547-Q549 WeakPolarHBondContact OD1-CB 3.48Å; N547-Q549 PolarHBondContact OD1-N 2.99Å; N547-T550 WeakPolarHBondContact CB-OG1 3.17Å; N547-T550 PolarHBondContact ND2-OG1 2.8Å; N547-T550 VanDerWaalsContact ND2-OG1 3.13Å; N547-T550 PolarHBondContact OD1-N 3.33Å; N547-T550 PolarHBondContact OD1-OG1 3.28Å; N547-G551 CarbonylContact O-C 3.58Å; N547-G551 VanDerWaalsContact O-CA 3.32Å; N547-G551 WeakPolarHBondContact O-CA 3.43Å; N547-G551 PolarHBondContact O-N 3.12Å; N547-E552 HydrophobicContact CB-CB 3.92Å; N547-E552 PolarHBondContact N-O 3.11Å; N547-E552 PolarHBondContact O-N 2.8Å; N547-E552 VanDerWaalsContact O-N 3.12Å
548G94.1Very high97.6Very high4 Ų445 Ų454%0.04124%0.24CC..THydrogen-bonded Turntrans-69.1-12.1175.600000114.6Q442Q442-G548 PolarHBondContact O-N 3.19Å
549Q92.6Very high97.5Very high101 Ų10153 Ų5347%0.47228%0.278SS..THydrogen-bonded Turntrans-83.3-49.6176.5-59.9-177.2-1.800111.1V439 Q442 V443 N547V439-Q549 PolarHBondContact O-NE2 3.44Å; Q442-Q549 HydrophobicContact CB-CG 4.02Å; V443-Q549 HydrophobicContact CG2-CB 4.37Å; V443-Q549 HydrophobicContact CG2-CG 3.87Å; N547-Q549 PolarHBondContact O-N 3Å; N547-Q549 WeakPolarHBondContact OD1-CA 3.46Å; N547-Q549 WeakPolarHBondContact OD1-CB 3.48Å; N547-Q549 PolarHBondContact OD1-N 2.99Å
550T94Very high97.5Very high92 Ų9250.7 Ų50.756%0.56429%0.286SS*.THydrogen-bonded Turntrans-86.9-21.2-18062.70000113.3N547 E552N547-T550 WeakPolarHBondContact CB-OG1 3.17Å; N547-T550 PolarHBondContact ND2-OG1 2.8Å; N547-T550 VanDerWaalsContact ND2-OG1 3.13Å; N547-T550 PolarHBondContact OD1-N 3.33Å; N547-T550 PolarHBondContact OD1-OG1 3.28Å; T550-E552 WeakPolarHBondContact OG1-CB 3.26Å; T550-E552 PolarHBondContact OG1-N 3.48Å
551G95.4Very high97.5Very high11 Ų1149.9 Ų49.911%0.11328%0.279CS..THydrogen-bonded Turntrans84.224.7-170.600000113.4V422 L423 S424 N547V422-G551 WeakPolarHBondContact O-CA 3.4Å; L423-G551 CarbonylContact C-O 3.49Å; L423-G551 VanDerWaalsContact CA-O 3.25Å; L423-G551 WeakPolarHBondContact CA-O 3.39Å; S424-G551 PolarHBondContact N-O 3.3Å; N547-G551 CarbonylContact O-C 3.58Å; N547-G551 VanDerWaalsContact O-CA 3.32Å; N547-G551 WeakPolarHBondContact O-CA 3.43Å; N547-G551 PolarHBondContact O-N 3.12Å
552E98.1Very high97.4Very high53 Ų5348.1 Ų48.125%0.24826%0.258CS..EExtended strand (participates in β ladder)trans-91.5135.8179.8-170.3-170.9165.900111.6S424 R545 N547 T550 T554S424-E552 WeakPolarHBondContact O-CA 3.43Å; R545-E552 VanDerWaalsContact CD-OE2 3.31Å; R545-E552 WeakPolarHBondContact CD-OE2 3.3Å; R545-E552 IonicContact CZ-OE1 3.89Å; R545-E552 IonicContact NH1-OE1 2.71Å; R545-E552 PolarHBondContact NH1-OE1 3.05Å; R545-E552 IonicContact NH1-OE2 2.73Å; N547-E552 HydrophobicContact CB-CB 3.92Å; N547-E552 PolarHBondContact N-O 3.11Å; N547-E552 PolarHBondContact O-N 2.8Å; N547-E552 VanDerWaalsContact O-N 3.12Å; T550-E552 WeakPolarHBondContact OG1-CB 3.26Å; T550-E552 PolarHBondContact OG1-N 3.48Å; E552-T554 WeakPolarHBondContact CG-OG1 3.41Å; E552-T554 WeakPolarHBondContact OE1-CB 3.28Å; E552-T554 PolarHBondContact OE1-OG1 2.97Å
553L98.7Very high97.3Very high0 Ų050.8 Ų50.80%028%0.283CS..EExtended strand (participates in β ladder)trans-133.398.3168.9-179.566.4000110.1L423 S424 G425 L427 A430 V507 A522 V525 R545 V546L423-L553 HydrophobicContact CB-CB 3.87Å; L423-L553 HydrophobicContact CD1-CB 4.47Å; S424-L553 PolarHBondContact O-N 2.93Å; G425-L553 CarbonylContact C-O 3.05Å; G425-L553 WeakPolarHBondContact CA-O 3.41Å; L427-L553 HydrophobicContact CB-CD2 4.08Å; L427-L553 HydrophobicContact CB-CG 3.97Å; L427-L553 HydrophobicContact CD1-CD1 4.08Å; L427-L553 HydrophobicContact CD1-CG 3.96Å; A430-L553 HydrophobicContact CB-CD2 3.85Å; V507-L553 HydrophobicContact CG1-CD1 4.46Å; V507-L553 HydrophobicContact CG2-CD1 4.12Å; A522-L553 HydrophobicContact CB-CD1 3.93Å; A522-L553 HydrophobicContact CB-CD2 4.19Å; V525-L553 HydrophobicContact CG2-CD2 4.06Å; R545-L553 WeakPolarHBondContact O-CA 3.31Å; V546-L553 HydrophobicContact CG2-CD1 3.92Å
554T98.6Very high97.2Very high27 Ų2751.9 Ų51.917%0.16630%0.3CS..EExtended strand (participates in β ladder)trans-127.4133.8-169.5-55.90000111.7N426 I544 R545 E552 L556N426-T554 VanDerWaalsContact OD1-CA 3.32Å; N426-T554 WeakPolarHBondContact OD1-CA 3.35Å; I544-T554 CarbonylContact C-O 3.57Å; I544-T554 WeakPolarHBondContact CA-O 3.4Å; R545-T554 PolarHBondContact N-O 2.83Å; R545-T554 PolarHBondContact O-N 2.68Å; E552-T554 WeakPolarHBondContact CG-OG1 3.41Å; E552-T554 WeakPolarHBondContact OE1-CB 3.28Å; E552-T554 PolarHBondContact OE1-OG1 2.97Å; T554-L556 HydrophobicContact CG2-CD1 4.06Å; T554-L556 WeakPolarHBondContact O-CD1 3.36Å
555L98.8Very high97.2Very high2 Ų252.3 Ų52.31%0.0130%0.302CS..EExtended strand (participates in β ladder)trans-90.1113.6163.3178.665.3000108.6N426 L427 L534 V538 D542 I544 V557 L562N426-L555 PolarHBondContact ND2-O 3Å; N426-L555 PolarHBondContact OD1-N 3.3Å; L427-L555 HydrophobicContact CD1-CB 4.1Å; L427-L555 HydrophobicContact CD2-CB 3.99Å; L427-L555 HydrophobicContact CD2-CD2 4.32Å; L427-L555 HydrophobicContact CG-CB 3.82Å; L534-L555 HydrophobicContact CD2-CD2 4.18Å; L534-L555 HydrophobicContact CG-CD2 4.27Å; V538-L555 HydrophobicContact CG1-CD1 4.47Å; V538-L555 HydrophobicContact CG2-CD1 4.23Å; V538-L555 HydrophobicContact CG2-CD2 3.99Å; D542-L555 HydrophobicContact CB-CD1 3.63Å; I544-L555 HydrophobicContact CD1-CD1 4.34Å; I544-L555 HydrophobicContact CG1-CD1 3.72Å; L555-V557 VanDerWaalsContact C-N 3.25Å; L555-V557 HydrophobicContact CD1-CG2 4.01Å; L555-V557 HydrophobicContact CD2-CG2 4.45Å; L555-V557 HydrophobicContact CG-CB 4.3Å; L555-V557 HydrophobicContact CG-CG2 3.89Å; L555-V557 PolarHBondContact O-N 2.73Å; L555-L562 HydrophobicContact CD2-CD1 4.35Å; L555-L562 HydrophobicContact CD2-CD2 3.54Å; L555-L562 HydrophobicContact CG-CD2 4.45Å
556L98.6Very high97.1Very high64 Ų6456.5 Ų56.534%0.33532%0.324SS..  trans-85.668.3-175.6-74.674.2000110.2I543 R545 T554I543-L556 HydrophobicContact CB-CB 4.06Å; I543-L556 HydrophobicContact CG2-CB 4.23Å; I543-L556 HydrophobicContact CG2-CD1 4.36Å; I543-L556 HydrophobicContact CG2-CD2 3.99Å; I543-L556 HydrophobicContact CG2-CG 4.44Å; I543-L556 PolarHBondContact O-N 2.84Å; R545-L556 HydrophobicContact CB-CD1 3.68Å; T554-L556 HydrophobicContact CG2-CD1 4.06Å; T554-L556 WeakPolarHBondContact O-CD1 3.36Å
557V98.3Very high97Very high20 Ų2058.7 Ų58.712%0.12134%0.338CS..SBendtrans-130.3138.8175.2178.40000107.4D542 L555 E561 L562D542-V557 HydrophobicContact CB-CG2 4.11Å; L555-V557 VanDerWaalsContact C-N 3.25Å; L555-V557 HydrophobicContact CD1-CG2 4.01Å; L555-V557 HydrophobicContact CD2-CG2 4.45Å; L555-V557 HydrophobicContact CG-CB 4.3Å; L555-V557 HydrophobicContact CG-CG2 3.89Å; L555-V557 PolarHBondContact O-N 2.73Å; V557-E561 HydrophobicContact CG1-CB 3.87Å; V557-E561 HydrophobicContact CG1-CG 3.95Å; V557-L562 HydrophobicContact CB-CD1 4.24Å; V557-L562 HydrophobicContact CB-CD2 3.83Å; V557-L562 HydrophobicContact CB-CG 3.89Å; V557-L562 HydrophobicContact CG1-CD2 3.77Å; V557-L562 HydrophobicContact CG1-CG 3.77Å
558D97.5Very high96.9Very high126 Ų12661.7 Ų61.767%0.67435%0.352SS*.  trans-57140.1-179.9-73.9-40.2000111.3A560 E561 L562D558-A560 PolarHBondContact O-N 2.84Å; D558-E561 WeakPolarHBondContact O-CB 3.45Å; D558-E561 PolarHBondContact O-N 3.48Å; D558-L562 PolarHBondContact O-N 3.26Å
559E96.9Very high96.9Very high171 Ų17168.6 Ų68.680%0.79939%0.386SS*.Hα-helixtrans-57.3-36.9-178.4-69.4-174.9169.500112.5E561 L562 A563E559-E561 VanDerWaalsContact C-N 3.33Å; E559-E561 PolarHBondContact O-N 3.44Å; E559-L562 PolarHBondContact O-N 3Å; E559-A563 VanDerWaalsContact O-CB 3.3Å; E559-A563 WeakPolarHBondContact O-CB 3.35Å; E559-A563 PolarHBondContact O-N 3.12Å
560A97.7Very high96.9Very high80 Ų8065 Ų6566%0.66137%0.372SS*.Hα-helixtrans-64.1-38.4177.300000112.1D558 A564D558-A560 PolarHBondContact O-N 2.84Å; A560-A564 PolarHBondContact O-N 2.9Å
561E98Very high96.9Very high88 Ų8867 Ų6741%0.41138%0.379SS..Hα-helixtrans-69.6-46.3175.4-174.7-177.3157.700110.4V557 D558 E559 A563 A564 R565V557-E561 HydrophobicContact CG1-CB 3.87Å; V557-E561 HydrophobicContact CG1-CG 3.95Å; D558-E561 WeakPolarHBondContact O-CB 3.45Å; D558-E561 PolarHBondContact O-N 3.48Å; E559-E561 VanDerWaalsContact C-N 3.33Å; E559-E561 PolarHBondContact O-N 3.44Å; E561-A563 VanDerWaalsContact C-N 3.27Å; E561-A563 PolarHBondContact O-N 2.8Å; E561-A564 PolarHBondContact O-N 3.46Å; E561-R565 WeakPolarHBondContact O-CG 3.47Å; E561-R565 PolarHBondContact O-N 3.37Å; E561-R565 IonicContact OE1-CZ 3.34Å; E561-R565 IonicContact OE1-NE 3.19Å; E561-R565 PolarHBondContact OE1-NE 3.44Å; E561-R565 IonicContact OE1-NH2 3.87Å; E561-R565 PolarHBondContact OE1-NH2 3.22Å
562L97.2Very high96.8Very high13 Ų1367.7 Ų67.77%0.06838%0.38CS..Hα-helixtrans-60.7-35.4177.2-69176.8000113L534 K537 L555 V557 D558 E559 A564 R565L534-L562 HydrophobicContact CD1-CD1 4.34Å; L534-L562 HydrophobicContact CD1-CD2 4.3Å; L534-L562 HydrophobicContact CD2-CD1 4.12Å; K537-L562 WeakPolarHBondContact CD-O 3.34Å; K537-L562 PolarHBondContact NZ-O 3.23Å; L555-L562 HydrophobicContact CD2-CD1 4.35Å; L555-L562 HydrophobicContact CD2-CD2 3.54Å; L555-L562 HydrophobicContact CG-CD2 4.45Å; V557-L562 HydrophobicContact CB-CD1 4.24Å; V557-L562 HydrophobicContact CB-CD2 3.83Å; V557-L562 HydrophobicContact CB-CG 3.89Å; V557-L562 HydrophobicContact CG1-CD2 3.77Å; V557-L562 HydrophobicContact CG1-CG 3.77Å; D558-L562 PolarHBondContact O-N 3.26Å; E559-L562 PolarHBondContact O-N 3Å; L562-A564 VanDerWaalsContact C-N 3.34Å; L562-R565 PolarHBondContact O-N 2.98Å
563A96.6Very high96.6Very high74 Ų7468.3 Ų68.361%0.61239%0.39SS*.Hα-helixtrans-65.3-37.8174.200000111.7E559 E561E559-A563 VanDerWaalsContact O-CB 3.3Å; E559-A563 WeakPolarHBondContact O-CB 3.35Å; E559-A563 PolarHBondContact O-N 3.12Å; E561-A563 VanDerWaalsContact C-N 3.27Å; E561-A563 PolarHBondContact O-N 2.8Å
564A97.7Very high96.2Very high80 Ų8071.6 Ų71.666%0.66142%0.417SS*.Hα-helixtrans-78.2-16.4178.700000114.2A560 E561 L562A560-A564 PolarHBondContact O-N 2.9Å; E561-A564 PolarHBondContact O-N 3.46Å; L562-A564 VanDerWaalsContact C-N 3.34Å
565R97.4Very high96Very high8 Ų871.2 Ų71.23%0.0342%0.415CS..PPolyproline II helixtrans-76.8130.2176.8-70.6-179.5-175.9-163.84.3111K537 D542 E561 L562K537-R565 HydrophobicContact CB-CB 4.38Å; K537-R565 HydrophobicContact CD-CB 4.11Å; K537-R565 WeakPolarHBondContact CD-O 3.41Å; K537-R565 WeakPolarHBondContact CE-O 3.42Å; K537-R565 PolarHBondContact NZ-O 2.99Å; K537-R565 PolarHBondContact O-NH1 3.29Å; D542-R565 IonicContact OD1-CZ 3.47Å; D542-R565 IonicContact OD1-NH1 3.4Å; D542-R565 PolarHBondContact OD1-NH1 3.26Å; D542-R565 IonicContact OD1-NH2 2.73Å; D542-R565 PolarHBondContact OD1-NH2 3.28Å; D542-R565 IonicContact OD2-CZ 3.6Å; D542-R565 IonicContact OD2-NH1 3.15Å; D542-R565 PolarHBondContact OD2-NH1 3.48Å; D542-R565 IonicContact OD2-NH2 3.85Å; E561-R565 WeakPolarHBondContact O-CG 3.47Å; E561-R565 PolarHBondContact O-N 3.37Å; E561-R565 IonicContact OE1-CZ 3.34Å; E561-R565 IonicContact OE1-NE 3.19Å; E561-R565 PolarHBondContact OE1-NE 3.44Å; E561-R565 IonicContact OE1-NH2 3.87Å; E561-R565 PolarHBondContact OE1-NH2 3.22Å; L562-R565 PolarHBondContact O-N 2.98Å
566E96.4Very high95.8Very high154 Ų15473.3 Ų73.372%0.7242%0.423SS*.PPolyproline II helixtrans-76.3139.5163.9-66-57.713800110.3
567P96.5Very high95.7Very high47 Ų4774.2 Ų74.231%0.30543%0.431SS..PPolyproline II helixtrans-64.9141.3172.229.1-33000110.3A536 K537 I569A536-P567 HydrophobicContact CB-CB 3.71Å; K537-P567 HydrophobicContact CG-CB 4.23Å; P567-I569 PolarHBondContact O-N 3.42Å
568H95.8Very high95.5Very high81 Ų8174.8 Ų74.838%0.37544%0.441SS..PPolyproline II helixtrans-66.6130.5170.9-177.367.9000109.9E452 R475 H476 A536E452-H568 IonicContact OE1-CD2 3.71Å; E452-H568 PolarHBondContact OE1-CD2 2.94Å; E452-H568 VanDerWaalsContact OE1-CD2 3.25Å; E452-H568 IonicContact OE1-NE2 3.56Å; E452-H568 IonicContact OE2-CD2 2.68Å; R475-H568 VanDerWaalsContact NH2-CB 3.32Å; R475-H568 PolarHBondContact NH2-CD2 3.17Å; R475-H568 VanDerWaalsContact NH2-CG 3.31Å; H476-H568 AromaticContact CE1-CD2 3.85Å; A536-H568 PolarHBondContact O-N 3.07Å
569I93.6Very high95.4Very high148 Ų14873.2 Ų73.276%0.75944%0.436SS*.  trans-105.2113.3175.4-57.9174.4000107.5P567P567-I569 PolarHBondContact O-N 3.42Å
570P92.3Very high95.4Very high26 Ų2666.1 Ų66.117%0.16941%0.408CS..  trans-78.9154.3-17835.1-39.1000111.4H476 L572H476-P570 HydrophobicContact CB-CB 4.44Å; H476-P570 HydrophobicContact CB-CG 4.14Å; H476-P570 WeakPolarHBondContact NE2-CD 3.31Å; P570-L572 HydrophobicContact CB-CD2 4.19Å; P570-L572 HydrophobicContact CB-CG 4.04Å; P570-L572 HydrophobicContact CG-CD1 3.77Å; P570-L572 HydrophobicContact CG-CD2 4.19Å; P570-L572 HydrophobicContact CG-CG 3.7Å; P570-L572 PolarHBondContact O-N 3Å
571D94.1Very high95.4Very high135 Ų13562.9 Ų62.972%0.72238%0.379SS*.  trans-85.1103.5159.7-178.74.1000109.4S573D571-S573 WeakPolarHBondContact OD1-CB 3.22Å; D571-S573 PolarHBondContact OD1-N 3.46Å; D571-S573 PolarHBondContact OD1-OG 3.37Å; D571-S573 PolarHBondContact OD2-OG 3.3Å
572L93.8Very high95.3Very high24 Ų2463.3 Ų63.313%0.12638%0.381CS..  trans-98.510.6178.8-64.6171.8000113H476 A481 Y530 P570 A574 S575 R576H476-L572 HydrophobicContact CB-CD2 4.42Å; A481-L572 HydrophobicContact CB-CD1 4.24Å; Y530-L572 HydrophobicContact CD2-CD1 3.55Å; Y530-L572 HydrophobicContact CE2-CD1 3.73Å; P570-L572 HydrophobicContact CB-CD2 4.19Å; P570-L572 HydrophobicContact CB-CG 4.04Å; P570-L572 HydrophobicContact CG-CD1 3.77Å; P570-L572 HydrophobicContact CG-CD2 4.19Å; P570-L572 HydrophobicContact CG-CG 3.7Å; P570-L572 PolarHBondContact O-N 3Å; L572-A574 PolarHBondContact O-N 3.34Å; L572-S575 PolarHBondContact O-N 2.99Å; L572-R576 WeakPolarHBondContact O-CG 3.34Å; L572-R576 PolarHBondContact O-N 3.27Å
573S93.4Very high95.3Very high67 Ų6769.4 Ų69.447%0.46941%0.413SS..G310 helixtrans-54-38.7-176.659.10000112.7D571 S575 R576D571-S573 WeakPolarHBondContact OD1-CB 3.22Å; D571-S573 PolarHBondContact OD1-N 3.46Å; D571-S573 PolarHBondContact OD1-OG 3.37Å; D571-S573 PolarHBondContact OD2-OG 3.3Å; S573-S575 PolarHBondContact O-N 2.82Å; S573-R576 WeakPolarHBondContact O-CB 3.4Å; S573-R576 PolarHBondContact O-N 3.39Å; S573-R576 VanDerWaalsContact O-N 3.14Å
574A92Very high95.4Very high68 Ų6867.6 Ų67.656%0.56239%0.391SS*.G310 helixtrans-64.3-35.1175.700000113.5L572 R576 R581L572-A574 PolarHBondContact O-N 3.34Å; A574-R576 PolarHBondContact O-N 3.19Å; A574-R581 PolarHBondContact O-NH1 2.95Å; A574-R581 PolarHBondContact O-NH2 2.91Å
575S93.1Very high95.3Very high19 Ų1965.3 Ų65.313%0.13337%0.371CS..G310 helixtrans-81.96.6175.7-64.70000113.3E123 L572 S573E123-S575 PolarHBondContact OE1-OG 2.85Å; E123-S575 WeakPolarHBondContact OE2-CB 3.49Å; L572-S575 PolarHBondContact O-N 2.99Å; S573-S575 PolarHBondContact O-N 2.82Å
576R95Very high95.3Very high46 Ų4668.4 Ų68.417%0.17440%0.398CS..G310 helixtrans-101.6-22.3176.2-61.9-70.9171.3-924.2113.1K480 A481 L572 S573 A574 R581 E582K480-R576 PolarHBondContact O-NH2 2.71Å; A481-R576 PolarHBondContact O-NH1 2.73Å; A481-R576 PolarHBondContact O-NH2 3.49Å; L572-R576 WeakPolarHBondContact O-CG 3.34Å; L572-R576 PolarHBondContact O-N 3.27Å; S573-R576 WeakPolarHBondContact O-CB 3.4Å; S573-R576 PolarHBondContact O-N 3.39Å; S573-R576 VanDerWaalsContact O-N 3.14Å; A574-R576 PolarHBondContact O-N 3.19Å; R576-R581 CarbonylContact O-C 3.34Å; R576-E582 WeakPolarHBondContact O-CA 3.35Å; R576-E582 PolarHBondContact O-N 3.45Å
577V95.6Very high95.3Very high84 Ų8463 Ų6351%0.50937%0.374SS..SBendtrans-133.2156.3-172.5-62.60000112.4R581 E582V577-R581 PolarHBondContact O-NE 3.24Å; V577-R581 PolarHBondContact O-NH2 2.61Å; V577-E582 WeakPolarHBondContact CA-OE2 3.32Å; V577-E582 HydrophobicContact CG1-CB 4.48Å
578G95.8Very high95.4Very high31 Ų3160.9 Ų60.932%0.3236%0.36SS..SBendtrans89.2148.8178.100000112.2G580 R581 E582G578-G580 PolarHBondContact O-N 3.2Å; G578-G580 VanDerWaalsContact O-N 3.12Å; G578-R581 WeakPolarHBondContact O-CB 3.15Å; G578-R581 VanDerWaalsContact O-CG 3.26Å; G578-R581 WeakPolarHBondContact O-CG 3.34Å; G578-R581 PolarHBondContact O-N 3.3Å; G578-R581 PolarHBondContact O-NE 2.75Å; G578-E582 PolarHBondContact N-OE2 3.13Å
579T94.9Very high95.4Very high94 Ų9462.8 Ų62.858%0.57737%0.369SS*.THydrogen-bonded Turntrans54.327.2-171.2-45.60000112.3L124 R581L124-T579 WeakPolarHBondContact CD1-O 3.38Å; T579-R581 VanDerWaalsContact C-N 3.34Å; T579-R581 PolarHBondContact O-N 2.82Å
580G96.4Very high95.6Very high21 Ų2162.9 Ų62.922%0.21636%0.364CS..THydrogen-bonded Turntrans77.77.7-178.900000115.4G578 E582 L583 F584G578-G580 PolarHBondContact O-N 3.2Å; G578-G580 VanDerWaalsContact O-N 3.12Å; G580-E582 PolarHBondContact O-N 3.37Å; G580-E582 VanDerWaalsContact O-N 3.11Å; G580-L583 WeakPolarHBondContact O-CB 3.41Å; G580-L583 PolarHBondContact O-N 2.93Å; G580-F584 WeakPolarHBondContact O-CD2 2.82Å
581R97.5Very high95.9Very high13 Ų1361.7 Ų61.75%0.04936%0.356CS..G310 helixtrans-56.4-27.6-179-75.6178.8-69-159.8-8.3114.3D120 E123 L124 A574 R576 V577 G578 T579 L583 F584 R588D120-R581 IonicContact OD2-CZ 2.74Å; D120-R581 IonicContact OD2-NH1 3.29Å; D120-R581 PolarHBondContact OD2-NH1 2.88Å; D120-R581 IonicContact OD2-NH2 2.74Å; D120-R581 PolarHBondContact OD2-NH2 3.04Å; E123-R581 IonicContact OE1-NH1 2.66Å; E123-R581 WeakPolarHBondContact OE2-CD 3.44Å; E123-R581 IonicContact OE2-CZ 2.71Å; E123-R581 IonicContact OE2-NE 3.59Å; E123-R581 IonicContact OE2-NH1 3.65Å; E123-R581 PolarHBondContact OE2-NH1 3.05Å; L124-R581 HydrophobicContact CD2-CG 4.03Å; L124-R581 HydrophobicContact CG-CG 4.28Å; A574-R581 PolarHBondContact O-NH1 2.95Å; A574-R581 PolarHBondContact O-NH2 2.91Å; R576-R581 CarbonylContact O-C 3.34Å; V577-R581 PolarHBondContact O-NE 3.24Å; V577-R581 PolarHBondContact O-NH2 2.61Å; G578-R581 WeakPolarHBondContact O-CB 3.15Å; G578-R581 VanDerWaalsContact O-CG 3.26Å; G578-R581 WeakPolarHBondContact O-CG 3.34Å; G578-R581 PolarHBondContact O-N 3.3Å; G578-R581 PolarHBondContact O-NE 2.75Å; T579-R581 VanDerWaalsContact C-N 3.34Å; T579-R581 PolarHBondContact O-N 2.82Å; R581-L583 PolarHBondContact O-N 2.94Å; R581-F584 PolarHBondContact O-N 3.07Å; R581-F584 VanDerWaalsContact O-N 3.16Å; R581-R588 PolarHBondContact O-NH2 3.48Å; R581-R588 VanDerWaalsContact O-NH2 3.14Å
582E96.6Very high96Very high97 Ų9756.8 Ų56.845%0.45333%0.332SS..G310 helixtrans-62.9-28.4176.857.6-84.4-168.500113R576 V577 G578 G580 F584 S585R576-E582 WeakPolarHBondContact O-CA 3.35Å; R576-E582 PolarHBondContact O-N 3.45Å; V577-E582 WeakPolarHBondContact CA-OE2 3.32Å; V577-E582 HydrophobicContact CG1-CB 4.48Å; G578-E582 PolarHBondContact N-OE2 3.13Å; G580-E582 PolarHBondContact O-N 3.37Å; G580-E582 VanDerWaalsContact O-N 3.11Å; E582-F584 PolarHBondContact O-N 3.44Å; E582-S585 PolarHBondContact O-OG 3.38Å
583L97.8Very high96.2Very high140 Ų14056.2 Ų56.273%0.73333%0.332SS*.G310 helixtrans-72.3-16.2177.8-58.6178.2000112.7G580 R581G580-L583 WeakPolarHBondContact O-CB 3.41Å; G580-L583 PolarHBondContact O-N 2.93Å; R581-L583 PolarHBondContact O-N 2.94Å
584F97.7Very high96.4Very high36 Ų3653 Ų5316%0.15831%0.31CS..G310 helixtrans-107.30.6-172.5-67.4-100.4000113.7L124 L127 V131 G580 R581 E582 A586 L587 R588L124-F584 HydrophobicContact CD1-CD2 4.17Å; L124-F584 HydrophobicContact CD1-CE2 3.79Å; L124-F584 HydrophobicContact CD1-CZ 4.31Å; L124-F584 HydrophobicContact CD2-CB 4.1Å; L124-F584 HydrophobicContact CD2-CD1 4.18Å; L124-F584 HydrophobicContact CD2-CD2 3.48Å; L124-F584 VanDerWaalsContact CD2-CD2 3.48Å; L124-F584 HydrophobicContact CD2-CE1 4.46Å; L124-F584 HydrophobicContact CD2-CE2 3.87Å; L124-F584 HydrophobicContact CD2-CG 3.67Å; L124-F584 HydrophobicContact CD2-CZ 4.33Å; L124-F584 HydrophobicContact CG-CD2 4.45Å; L124-F584 HydrophobicContact CG-CE2 4.4Å; L127-F584 HydrophobicContact CB-CD1 3.81Å; L127-F584 HydrophobicContact CB-CE1 4.18Å; L127-F584 HydrophobicContact CD1-CB 3.93Å; L127-F584 HydrophobicContact CD1-CD1 4.18Å; L127-F584 HydrophobicContact CD1-CG 4.34Å; L127-F584 HydrophobicContact CD2-CD1 4.43Å; L127-F584 HydrophobicContact CG-CD1 4.37Å; V131-F584 HydrophobicContact CG2-CD1 4.38Å; V131-F584 HydrophobicContact CG2-CE1 3.55Å; V131-F584 HydrophobicContact CG2-CZ 4.3Å; G580-F584 WeakPolarHBondContact O-CD2 2.82Å; R581-F584 PolarHBondContact O-N 3.07Å; R581-F584 VanDerWaalsContact O-N 3.16Å; E582-F584 PolarHBondContact O-N 3.44Å; F584-A586 VanDerWaalsContact C-N 3.31Å; F584-A586 PolarHBondContact O-N 3.38Å; F584-L587 HydrophobicContact CD1-CD1 4.18Å; F584-L587 PolarHBondContact O-N 3.49Å; F584-R588 WeakPolarHBondContact O-CB 3.41Å; F584-R588 PolarHBondContact O-N 3.08Å
585S96.4Very high96.7Very high32 Ų3250.9 Ų50.922%0.22429%0.288CS..Hα-helixtrans-54.8-45.9-176-60.70000112.6E582 L587 R588 E589E582-S585 PolarHBondContact O-OG 3.38Å; S585-L587 VanDerWaalsContact C-N 3.31Å; S585-L587 PolarHBondContact O-N 3.47Å; S585-R588 PolarHBondContact O-N 3.25Å; S585-E589 WeakPolarHBondContact O-CG 3.5Å; S585-E589 PolarHBondContact O-N 3.35Å
586A96.4Very high96.9Very high74 Ų7453.5 Ų53.561%0.61230%0.299SS*.Hα-helixtrans-62.6-35.8178.600000113.2F584 K590F584-A586 VanDerWaalsContact C-N 3.31Å; F584-A586 PolarHBondContact O-N 3.38Å; A586-K590 WeakPolarHBondContact O-CG 3.47Å
587L97.5Very high97Very high39 Ų3951.3 Ų51.320%0.20429%0.29CS..Hα-helixtrans-74.5-45.3176.6-62.1-179.6000110.9L127 V131 M134 F584 S585 E589 K590 L591L127-L587 HydrophobicContact CD2-CB 3.71Å; V131-L587 HydrophobicContact CG2-CD1 4.25Å; M134-L587 HydrophobicContact CE-CD2 3.89Å; F584-L587 HydrophobicContact CD1-CD1 4.18Å; F584-L587 PolarHBondContact O-N 3.49Å; S585-L587 VanDerWaalsContact C-N 3.31Å; S585-L587 PolarHBondContact O-N 3.47Å; L587-E589 VanDerWaalsContact C-N 3.35Å; L587-E589 PolarHBondContact O-N 2.8Å; L587-K590 CarbonylContact O-C 3.45Å; L587-K590 PolarHBondContact O-N 3.31Å; L587-L591 PolarHBondContact O-N 3.23Å
588R97.7Very high97.1Very high3 Ų347.3 Ų47.31%0.01127%0.266CS..Hα-helixtrans-57.8-46.1-178.5-168.9-173.9-60.31061.6111.6L127 P479 K480 R581 F584 S585 K590 L591L127-R588 HydrophobicContact CD1-CB 4.37Å; P479-R588 WeakPolarHBondContact O-CG 3.25Å; K480-R588 WeakPolarHBondContact O-CD 3.33Å; R581-R588 PolarHBondContact O-NH2 3.48Å; R581-R588 VanDerWaalsContact O-NH2 3.14Å; F584-R588 WeakPolarHBondContact O-CB 3.41Å; F584-R588 PolarHBondContact O-N 3.08Å; S585-R588 PolarHBondContact O-N 3.25Å; R588-K590 PolarHBondContact O-N 2.9Å; R588-L591 PolarHBondContact O-N 2.78Å
589E96Very high97.2Very high122 Ų12246.3 Ų46.357%0.5725%0.254SS*.THydrogen-bonded Turntrans-63.8-20.6178.5-72.3172.9-170.200113.6S585 L587S585-E589 WeakPolarHBondContact O-CG 3.5Å; S585-E589 PolarHBondContact O-N 3.35Å; L587-E589 VanDerWaalsContact C-N 3.35Å; L587-E589 PolarHBondContact O-N 2.8Å
590K97.3Very high97.3Very high150 Ų15042.9 Ų42.965%0.65223%0.233SC*.THydrogen-bonded Turntrans-100.6-2.9-179.2-64.9-60-178.1-170.80114A586 L587 R588 S592 C600A586-K590 WeakPolarHBondContact O-CG 3.47Å; L587-K590 CarbonylContact O-C 3.45Å; L587-K590 PolarHBondContact O-N 3.31Å; R588-K590 PolarHBondContact O-N 2.9Å; K590-S592 PolarHBondContact O-N 3.19Å; K590-C600 HydrophobicContact CB-CB 3.86Å; K590-C600 WeakPolarHBondContact O-CA 3.46Å
591L98.2Very high97.4Very high1 Ų143.6 Ų43.61%0.00523%0.232CC..PPolyproline II helixtrans-60.8131.6174.5-68.9172.8000110.1L127 E130 P479 K480 L587 R588 A598 C600L127-L591 HydrophobicContact CD2-CD1 3.87Å; L127-L591 HydrophobicContact CD2-CD2 4.33Å; L127-L591 HydrophobicContact CD2-CG 4.28Å; L127-L591 HydrophobicContact CG-CD1 4.23Å; E130-L591 HydrophobicContact CG-CD2 4.46Å; P479-L591 HydrophobicContact CB-CB 3.7Å; P479-L591 HydrophobicContact CB-CD1 3.91Å; P479-L591 HydrophobicContact CB-CG 4.43Å; P479-L591 WeakPolarHBondContact O-CD1 3.46Å; K480-L591 WeakPolarHBondContact CE-O 3.28Å; L587-L591 PolarHBondContact O-N 3.23Å; R588-L591 PolarHBondContact O-N 2.78Å; L591-A598 WeakPolarHBondContact CD2-O 3.36Å; L591-C600 HydrophobicContact CD2-CB 4.13Å
592S97.8Very high97.2Very high31 Ų3149.6 Ų49.622%0.21727%0.27CS..PPolyproline II helixtrans-67.7171.1168.472.70000111.4K590 A598 T599K590-S592 PolarHBondContact O-N 3.19Å; S592-A598 WeakPolarHBondContact O-CA 3.49Å; S592-A598 WeakPolarHBondContact OG-CA 3.31Å; S592-A598 PolarHBondContact OG-N 2.87Å; S592-T599 PolarHBondContact N-O 3.1Å; S592-T599 PolarHBondContact OG-N 3.31Å; S592-T599 VanDerWaalsContact OG-N 3.1Å
593G97Very high96.9Very high13 Ų1348.4 Ų48.413%0.13426%0.263CS..PPolyproline II helixtrans-60.9164.3166.500000112.3E595 Q596 A598G593-E595 PolarHBondContact O-N 3.35Å; G593-Q596 VanDerWaalsContact CA-OE1 3.24Å; G593-Q596 PolarHBondContact O-N 2.95Å; G593-Q596 VanDerWaalsContact O-N 3.15Å; G593-Q596 PolarHBondContact O-OE1 2.72Å; G593-A598 WeakPolarHBondContact O-CA 3.33Å; G593-A598 PolarHBondContact O-N 3.01Å
594A97.8Very high96.8Very high0 Ų043.8 Ų43.80%024%0.24CC..THydrogen-bonded Turntrans-63.3-42.9-17500000112.4M305 W320 M484 H524 T526 Q596 G597M305-A594 HydrophobicContact CG-CB 4.22Å; M305-A594 WeakPolarHBondContact CG-O 3.27Å; M305-A594 HydrophobicContact SD-CB 3.82Å; W320-A594 HydrophobicContact CH2-CB 4.35Å; W320-A594 HydrophobicContact CZ2-CB 4.22Å; M484-A594 HydrophobicContact SD-CB 4.39Å; H524-A594 HydrophobicContact CB-CB 3.66Å; T526-A594 PolarHBondContact OG1-N 2.84Å; A594-Q596 PolarHBondContact O-N 2.95Å; A594-Q596 VanDerWaalsContact O-N 3.17Å; A594-G597 WeakPolarHBondContact O-CA 3.13Å; A594-G597 PolarHBondContact O-N 2.84Å
595E97.4Very high96.8Very high22 Ų2244.2 Ų44.210%0.10324%0.244CC..THydrogen-bonded Turntrans-59.9-29.2176.5-177.8166.6-156.300112.8W320 R429 G593 G597W320-E595 HydrophobicContact CB-CG 4.33Å; W320-E595 WeakPolarHBondContact CB-OE1 3.41Å; W320-E595 HydrophobicContact CD2-CB 3.8Å; W320-E595 HydrophobicContact CD2-CG 3.69Å; W320-E595 HydrophobicContact CE3-CB 3.85Å; W320-E595 HydrophobicContact CE3-CG 3.92Å; W320-E595 HydrophobicContact CG-CB 4.45Å; W320-E595 HydrophobicContact CG-CG 3.86Å; W320-E595 HydrophobicContact CH2-CB 3.94Å; W320-E595 HydrophobicContact CZ2-CB 3.9Å; W320-E595 HydrophobicContact CZ3-CB 3.9Å; W320-E595 HydrophobicContact CZ3-CG 4.48Å; W320-E595 PolarHBondContact N-OE1 2.96Å; R429-E595 WeakPolarHBondContact CD-OE2 3.41Å; R429-E595 IonicContact CZ-OE1 3.91Å; R429-E595 IonicContact CZ-OE2 2.82Å; R429-E595 IonicContact NE-OE1 3.16Å; R429-E595 PolarHBondContact NE-OE1 3.22Å; R429-E595 VanDerWaalsContact NE-OE1 3.13Å; R429-E595 IonicContact NE-OE2 3.71Å; R429-E595 PolarHBondContact NE-OE2 3.35Å; R429-E595 IonicContact NH2-OE1 3.47Å; R429-E595 PolarHBondContact NH2-OE1 3.44Å; G593-E595 PolarHBondContact O-N 3.35Å; E595-G597 PolarHBondContact O-N 2.79Å
596Q97.4Very high96.8Very high75 Ų7544.9 Ų44.935%0.3525%0.245SC..THydrogen-bonded Turntrans-84.57.5176.8-6178.429.400113.3R312 G593 A594R312-Q596 PolarHBondContact NH1-O 2.87Å; G593-Q596 VanDerWaalsContact CA-OE1 3.24Å; G593-Q596 PolarHBondContact O-N 2.95Å; G593-Q596 VanDerWaalsContact O-N 3.15Å; G593-Q596 PolarHBondContact O-OE1 2.72Å; A594-Q596 PolarHBondContact O-N 2.95Å; A594-Q596 VanDerWaalsContact O-N 3.17Å
597G97.8Very high96.8Very high0 Ų043.2 Ų43.20%022%0.224CC..THydrogen-bonded Turntrans97.62.1177.100000114.6R129 M305 A594 E595 T599R129-G597 PolarHBondContact NH1-O 3.39Å; R129-G597 PolarHBondContact NH2-O 3.49Å; R129-G597 VanDerWaalsContact NH2-O 3.15Å; M305-G597 WeakPolarHBondContact O-CA 3.35Å; A594-G597 WeakPolarHBondContact O-CA 3.13Å; A594-G597 PolarHBondContact O-N 2.84Å; E595-G597 PolarHBondContact O-N 2.79Å; G597-T599 VanDerWaalsContact C-N 3.29Å; G597-T599 PolarHBondContact O-N 3.03Å
598A98.1Very high96.8Very high0 Ų043.4 Ų43.40%023%0.225CC..SBendtrans41.556.2-172.900000112.1L126 R129 M305 P479 L591 S592 G593L126-A598 HydrophobicContact CD2-CB 3.69Å; R129-A598 PolarHBondContact NH2-O 3.24Å; M305-A598 HydrophobicContact SD-CB 4.24Å; P479-A598 HydrophobicContact CB-CB 4.25Å; P479-A598 HydrophobicContact CG-CB 3.81Å; L591-A598 WeakPolarHBondContact CD2-O 3.36Å; S592-A598 WeakPolarHBondContact O-CA 3.49Å; S592-A598 WeakPolarHBondContact OG-CA 3.31Å; S592-A598 PolarHBondContact OG-N 2.87Å; G593-A598 WeakPolarHBondContact O-CA 3.33Å; G593-A598 PolarHBondContact O-N 3.01Å
599T98.1Very high96.7Very high10 Ų1046.1 Ų46.16%0.06124%0.239CC..  trans-117.5146.9-178.2-176.50000110.2R129 E130 S592 G597 I601R129-T599 VanDerWaalsContact NH2-CA 3.32Å; R129-T599 VanDerWaalsContact NH2-CB 3.27Å; E130-T599 WeakPolarHBondContact OE2-CA 3.28Å; E130-T599 PolarHBondContact OE2-OG1 2.92Å; S592-T599 PolarHBondContact N-O 3.1Å; S592-T599 PolarHBondContact OG-N 3.31Å; S592-T599 VanDerWaalsContact OG-N 3.1Å; G597-T599 VanDerWaalsContact C-N 3.29Å; G597-T599 PolarHBondContact O-N 3.03Å; T599-I601 PolarHBondContact OG1-N 3.47Å
600C97.6Very high96.8Very high22 Ų2240.7 Ų40.715%0.14922%0.216CC..  trans-100.2-6.6171.766.40000112.4E130 K590 L591E130-C600 PolarHBondContact OE2-N 2.58Å; E130-C600 PolarHBondContact OE2-SG 2.99Å; K590-C600 HydrophobicContact CB-CB 3.86Å; K590-C600 WeakPolarHBondContact O-CA 3.46Å; L591-C600 HydrophobicContact CD2-CB 4.13Å
601I97.3Very high96.7Very high36 Ų3632.3 Ų32.319%0.18518%0.182CC..  trans-86.9126-178.6-61.8167.1000109.3E130 A133 M134 M163 T599 F603E130-I601 HydrophobicContact CB-CD1 4.41Å; E130-I601 PolarHBondContact OE2-N 2.64Å; A133-I601 HydrophobicContact CB-CD1 3.95Å; M134-I601 HydrophobicContact CE-CD1 4.2Å; M134-I601 HydrophobicContact CE-CG1 3.89Å; M163-I601 HydrophobicContact CE-CD1 3.74Å; T599-I601 PolarHBondContact OG1-N 3.47Å; I601-F603 HydrophobicContact CB-CE1 4.5Å; I601-F603 HydrophobicContact CB-CE2 3.94Å; I601-F603 HydrophobicContact CB-CZ 3.89Å; I601-F603 HydrophobicContact CG2-CD1 3.97Å; I601-F603 HydrophobicContact CG2-CD2 4.13Å; I601-F603 HydrophobicContact CG2-CE1 3.55Å; I601-F603 HydrophobicContact CG2-CE2 3.73Å; I601-F603 HydrophobicContact CG2-CG 4.25Å; I601-F603 HydrophobicContact CG2-CZ 3.42Å; I601-F603 VanDerWaalsContact CG2-CZ 3.42Å
602T92.7Very high96.6Very high138 Ų13834.9 Ų34.985%0.84720%0.197SC*.  trans-95.3118.8171.853.50000109.2
603F90.4Very high96.5Very high72 Ų7235.3 Ų35.332%0.31620%0.195SC..  trans-98.20-172.5-69.6-75000114.7R26 M163 R312 A313 I601R26-F603 PolarHBondContact NH1-OXT 3.16Å; R26-F603 PolarHBondContact NH2-OXT 3.14Å; M163-F603 HydrophobicContact CB-CZ 4.17Å; M163-F603 HydrophobicContact CE-CE2 4.05Å; M163-F603 HydrophobicContact CE-CZ 3.66Å; M163-F603 HydrophobicContact CG-CZ 4.23Å; R312-F603 HydrophobicContact CB-CD2 4.41Å; R312-F603 HydrophobicContact CG-CD2 4Å; A313-F603 HydrophobicContact CB-CD1 3.83Å; A313-F603 HydrophobicContact CB-CD2 4.33Å; A313-F603 HydrophobicContact CB-CE1 3.53Å; A313-F603 HydrophobicContact CB-CE2 4.06Å; A313-F603 HydrophobicContact CB-CG 4.22Å; A313-F603 HydrophobicContact CB-CZ 3.64Å; I601-F603 HydrophobicContact CB-CE1 4.5Å; I601-F603 HydrophobicContact CB-CE2 3.94Å; I601-F603 HydrophobicContact CB-CZ 3.89Å; I601-F603 HydrophobicContact CG2-CD1 3.97Å; I601-F603 HydrophobicContact CG2-CD2 4.13Å; I601-F603 HydrophobicContact CG2-CE1 3.55Å; I601-F603 HydrophobicContact CG2-CE2 3.73Å; I601-F603 HydrophobicContact CG2-CG 4.25Å; I601-F603 HydrophobicContact CG2-CZ 3.42Å; I601-F603 VanDerWaalsContact CG2-CZ 3.42Å

Retrieved 603 of 603 residues in 995.8 ms (Link to these results)