A0A077ZIT0_TRITR Loading...

Moesin/ezrin/radixin homolog 1

AlphaFold DB , UniProt , Accession A0A077ZIT0, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 466 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M86.6Confident94.5Very high125 Ų12546 Ų4662%0.61624%0.243SC*.  0-600-88.7-140.8-96.700113.7D3 R41M1-D3 VanDerWaalsContact C-N 3.31Å; M1-R41 PolarHBondContact O-NH2 2.88Å; M1-R41 HydrophobicContact SD-CB 3.88Å; M1-R41 HydrophobicContact SD-CG 3.64Å
2S92.4Very high94.7Very high70 Ų7042.8 Ų42.849%0.4923%0.227SC..  trans-81.3-5.7177.646.50000114.6E4S2-E4 WeakPolarHBondContact CB-OE1 3.29Å; S2-E4 PolarHBondContact O-N 2.66Å; S2-E4 PolarHBondContact OG-OE1 2.83Å
3D92.6Very high94.9Very high58 Ų5839.6 Ų39.631%0.3121%0.21SC..SBendtrans62.114.7-174-125.131.6000115.2M1 I5 P44 R46M1-D3 VanDerWaalsContact C-N 3.31Å; D3-I5 PolarHBondContact O-N 3.11Å; D3-P44 HydrophobicContact CB-CB 4.16Å; D3-P44 VanDerWaalsContact OD1-CB 3.29Å; D3-P44 WeakPolarHBondContact OD1-CB 3.39Å; D3-P44 WeakPolarHBondContact OD1-CG 3.29Å; D3-R46 IonicContact OD1-CZ 3.14Å; D3-R46 IonicContact OD1-NE 2.71Å; D3-R46 IonicContact OD1-NH2 3.99Å; D3-R46 PolarHBondContact OD1-NH2 3.42Å; D3-R46 IonicContact OD2-CZ 3.13Å; D3-R46 IonicContact OD2-NE 2.67Å; D3-R46 PolarHBondContact OD2-NE 2.56Å; D3-R46 IonicContact OD2-NH2 2.64Å
4E94.2Very high95Very high147 Ų14736.8 Ų36.869%0.68720%0.195SC*.SBendtrans-59.3-34.6166.6-71166.4-110.600112.9S2 M90S2-E4 WeakPolarHBondContact CB-OE1 3.29Å; S2-E4 PolarHBondContact O-N 2.66Å; S2-E4 PolarHBondContact OG-OE1 2.83Å; E4-M90 WeakPolarHBondContact O-CE 3.2Å
5I96.4Very high95.2Very high70 Ų7034.9 Ų34.936%0.35919%0.185SC..SBendtrans-111.8119.3172-66.2172000105.9D3 C7 L88 M90 Y91D3-I5 PolarHBondContact O-N 3.11Å; I5-C7 PolarHBondContact O-N 2.66Å; I5-L88 HydrophobicContact CG2-CB 4.4Å; I5-L88 HydrophobicContact CG2-CD1 4.08Å; I5-M90 HydrophobicContact CG2-CB 4.17Å; I5-Y91 HydrophobicContact CD1-CD2 4.45Å
6Y97.5Very high95.3Very high6 Ų633 Ų332%0.02418%0.176CC..  trans-59.8134.5171.1175.9-95000110.4P8 M90 L124 Y429 D430 H433Y6-P8 HydrophobicContact CE1-CB 4.17Å; Y6-M90 PolarHBondContact N-SD 3.09Å; Y6-M90 VanDerWaalsContact N-SD 3.41Å; Y6-L124 HydrophobicContact CD1-CD1 4.16Å; Y6-L124 HydrophobicContact CD1-CD2 4.11Å; Y6-L124 HydrophobicContact CE1-CD1 4.44Å; Y6-L124 HydrophobicContact CG-CD2 4.14Å; Y6-Y429 HydrophobicContact CD2-CG 4.23Å; Y6-D430 WeakPolarHBondContact CE2-OD1 3.42Å; Y6-D430 PolarHBondContact OH-OD1 2.91Å; Y6-H433 HydrophobicContact CE1-CB 3.6Å; Y6-H433 AromaticContact CE1-CG 3.56Å; Y6-H433 AromaticContact CE1-ND1 3.81Å
7C97.2Very high95.4Very high12 Ų1231.1 Ų31.18%0.08117%0.165CC..  trans-138.6129.2173.6-173.40000108I5 T12 R46 L88I5-C7 PolarHBondContact O-N 2.66Å; C7-T12 PolarHBondContact SG-OG1 3.25Å; C7-R46 PolarHBondContact O-NH1 2.99Å; C7-R46 PolarHBondContact O-NH2 3.14Å; C7-L88 HydrophobicContact CB-CD1 4Å
8P96.3Very high95.5Very high3 Ų330 Ų302%0.01916%0.159CC..  trans-72.7159.8179.233.1-36.8000110.9Y6 E10 T11 T12Y6-P8 HydrophobicContact CE1-CB 4.17Å; P8-E10 WeakPolarHBondContact CB-OE2 3.45Å; P8-E10 WeakPolarHBondContact CG-OE1 3.41Å; P8-E10 PolarHBondContact O-N 3.19Å; P8-T11 PolarHBondContact O-N 3.1Å; P8-T12 WeakPolarHBondContact O-CB 3.44Å; P8-T12 PolarHBondContact O-N 3.2Å; P8-T12 PolarHBondContact O-OG1 2.65Å
9P95.7Very high95.6Very high4 Ų430.2 Ų30.23%0.02617%0.165CC..Hα-helixtrans-61.2-42.8-169.3-29.541000114.9T12 V13 V47 Y51 L417P9-T12 WeakPolarHBondContact O-CB 3.43Å; P9-T12 PolarHBondContact O-N 2.97Å; P9-V13 PolarHBondContact O-N 3.28Å; P9-V13 VanDerWaalsContact O-N 3.09Å; P9-V47 HydrophobicContact CB-CG1 3.99Å; P9-V47 HydrophobicContact CG-CG1 4.46Å; P9-Y51 HydrophobicContact CB-CE2 3.75Å; P9-Y51 HydrophobicContact CG-CE2 3.6Å; P9-Y51 WeakPolarHBondContact CG-OH 2.96Å; P9-L417 HydrophobicContact CB-CD1 3.97Å
10E94.7Very high95.7Very high4 Ų429 Ų292%0.01916%0.158CC..Hα-helixtrans-65.2-44.6179.374.9-67.7174.500112P8 T12 V13 L14 L410 L413 N414 L417 K437P8-E10 WeakPolarHBondContact CB-OE2 3.45Å; P8-E10 WeakPolarHBondContact CG-OE1 3.41Å; P8-E10 PolarHBondContact O-N 3.19Å; E10-T12 VanDerWaalsContact C-N 3.26Å; E10-T12 PolarHBondContact O-N 2.77Å; E10-V13 PolarHBondContact O-N 3.02Å; E10-L14 PolarHBondContact O-N 2.92Å; E10-L14 VanDerWaalsContact O-N 3.15Å; E10-L410 HydrophobicContact CB-CD2 4.16Å; E10-L410 HydrophobicContact CG-CB 4.32Å; E10-L410 HydrophobicContact CG-CD2 4.12Å; E10-L413 HydrophobicContact CB-CD2 3.98Å; E10-L413 HydrophobicContact CB-CG 4.16Å; E10-N414 HydrophobicContact CB-CB 4.06Å; E10-N414 HydrophobicContact CG-CB 4.07Å; E10-L417 HydrophobicContact CB-CD1 4.49Å; E10-K437 IonicContact OE1-NZ 2.75Å; E10-K437 PolarHBondContact OE1-NZ 3.03Å
11T96.3Very high95.7Very high7 Ų727.6 Ų27.64%0.04315%0.151CC..Hα-helixtrans-67.2-30.7174.6-56.20000111.2P8 L14 L15 I84 L88P8-T11 PolarHBondContact O-N 3.1Å; T11-L14 PolarHBondContact O-N 3.08Å; T11-L15 HydrophobicContact CG2-CD1 4.04Å; T11-L15 HydrophobicContact CG2-CG 4.19Å; T11-L15 VanDerWaalsContact O-CB 3.31Å; T11-L15 WeakPolarHBondContact O-CB 3.01Å; T11-L15 VanDerWaalsContact O-CG 3.25Å; T11-L15 WeakPolarHBondContact O-CG 3.27Å; T11-L15 PolarHBondContact O-N 2.82Å; T11-I84 HydrophobicContact CG2-CG2 3.74Å; T11-L88 HydrophobicContact CG2-CD2 4.25Å
12T96.9Very high96.2Very high8 Ų822.6 Ų22.65%0.04913%0.129CC..Hα-helixtrans-64.5-41.9174.6-60.10000111.7C7 P8 P9 E10 A16 M43 V47C7-T12 PolarHBondContact SG-OG1 3.25Å; P8-T12 WeakPolarHBondContact O-CB 3.44Å; P8-T12 PolarHBondContact O-N 3.2Å; P8-T12 PolarHBondContact O-OG1 2.65Å; P9-T12 WeakPolarHBondContact O-CB 3.43Å; P9-T12 PolarHBondContact O-N 2.97Å; E10-T12 VanDerWaalsContact C-N 3.26Å; E10-T12 PolarHBondContact O-N 2.77Å; T12-A16 WeakPolarHBondContact O-CB 3.33Å; T12-A16 PolarHBondContact O-N 3.03Å; T12-M43 HydrophobicContact CG2-CB 3.58Å; T12-V47 HydrophobicContact CG2-CG1 4.3Å; T12-V47 HydrophobicContact CG2-CG2 4.38Å
13V96.7Very high96.3Very high1 Ų125.5 Ų25.51%0.00613%0.129CC..Hα-helixtrans-63.1-46.3174.3172.20000111.1P9 E10 A16 S17 W58 I62 L413P9-V13 PolarHBondContact O-N 3.28Å; P9-V13 VanDerWaalsContact O-N 3.09Å; E10-V13 PolarHBondContact O-N 3.02Å; V13-A16 WeakPolarHBondContact O-CB 3.43Å; V13-A16 PolarHBondContact O-N 2.85Å; V13-S17 PolarHBondContact O-N 3.34Å; V13-W58 HydrophobicContact CG2-CE3 4.02Å; V13-W58 HydrophobicContact CG2-CZ3 3.58Å; V13-I62 HydrophobicContact CG1-CG1 3.96Å; V13-L413 HydrophobicContact CB-CD2 3.86Å; V13-L413 HydrophobicContact CG1-CD2 3.9Å; V13-L413 HydrophobicContact CG2-CD2 4.31Å
14L96.8Very high96.4Very high0 Ų026 Ų260%013%0.128CC..Hα-helixtrans-62.8-47179.1-179.359.4000111.6E10 T11 A16 S17 Y18 W65 I84 I406 L410E10-L14 PolarHBondContact O-N 2.92Å; E10-L14 VanDerWaalsContact O-N 3.15Å; T11-L14 PolarHBondContact O-N 3.08Å; L14-A16 VanDerWaalsContact C-N 3.31Å; L14-A16 PolarHBondContact O-N 2.88Å; L14-S17 PolarHBondContact O-N 3.21Å; L14-S17 VanDerWaalsContact O-N 3.14Å; L14-S17 PolarHBondContact O-OG 3.4Å; L14-Y18 HydrophobicContact CD1-CD2 4.08Å; L14-Y18 HydrophobicContact CD1-CE2 3.54Å; L14-Y18 HydrophobicContact CD2-CE2 4.34Å; L14-Y18 HydrophobicContact CG-CD2 4.09Å; L14-Y18 HydrophobicContact CG-CE2 3.74Å; L14-Y18 WeakPolarHBondContact O-CD2 3.31Å; L14-Y18 PolarHBondContact O-N 3.39Å; L14-Y18 VanDerWaalsContact O-N 3.13Å; L14-W65 HydrophobicContact CD1-CD2 4.06Å; L14-W65 HydrophobicContact CD1-CE3 3.58Å; L14-W65 HydrophobicContact CD1-CZ3 3.85Å; L14-I84 HydrophobicContact CD2-CD1 3.8Å; L14-I84 HydrophobicContact CG-CD1 4.19Å; L14-I406 HydrophobicContact CD2-CG2 3.7Å; L14-L410 HydrophobicContact CB-CD2 3.96Å; L14-L410 HydrophobicContact CD2-CD1 3.85Å; L14-L410 HydrophobicContact CD2-CD2 3.92Å; L14-L410 HydrophobicContact CD2-CG 4.13Å
15L97.4Very high96.4Very high8 Ų820.3 Ų20.34%0.04211%0.106CC..Hα-helixtrans-60.6-38.1174.7-72.9178000112.2T11 S17 Y18 A19 Y81 I84 A85T11-L15 HydrophobicContact CG2-CD1 4.04Å; T11-L15 HydrophobicContact CG2-CG 4.19Å; T11-L15 VanDerWaalsContact O-CB 3.31Å; T11-L15 WeakPolarHBondContact O-CB 3.01Å; T11-L15 VanDerWaalsContact O-CG 3.25Å; T11-L15 WeakPolarHBondContact O-CG 3.27Å; T11-L15 PolarHBondContact O-N 2.82Å; L15-S17 PolarHBondContact O-N 3.17Å; L15-Y18 PolarHBondContact O-N 2.95Å; L15-A19 WeakPolarHBondContact O-CB 3.32Å; L15-A19 PolarHBondContact O-N 2.96Å; L15-Y81 HydrophobicContact CB-CD2 4.02Å; L15-Y81 HydrophobicContact CB-CE2 3.65Å; L15-Y81 HydrophobicContact CD2-CD1 4.17Å; L15-Y81 HydrophobicContact CD2-CD2 3.77Å; L15-Y81 HydrophobicContact CD2-CE1 4.34Å; L15-Y81 HydrophobicContact CD2-CE2 3.99Å; L15-Y81 HydrophobicContact CD2-CG 3.85Å; L15-Y81 VanDerWaalsContact CD2-O 3.31Å; L15-Y81 WeakPolarHBondContact CD2-O 3.36Å; L15-Y81 HydrophobicContact CG-CD2 4.48Å; L15-Y81 HydrophobicContact CG-CE2 4.29Å; L15-Y81 VanDerWaalsContact O-CD2 3.23Å; L15-Y81 WeakPolarHBondContact O-CD2 3.32Å; L15-Y81 WeakPolarHBondContact O-CE2 3.42Å; L15-I84 HydrophobicContact CD2-CB 4.01Å; L15-I84 HydrophobicContact CD2-CG2 3.99Å; L15-I84 HydrophobicContact CG-CG2 4.38Å; L15-A85 HydrophobicContact CD1-CB 4.3Å; L15-A85 HydrophobicContact CD2-CB 4.25Å
16A97.4Very high96.3Very high5 Ų518.9 Ų18.94%0.04110%0.099CC..Hα-helixtrans-62.7-40.317400000112.2T12 V13 L14 A19 M20 L42 I62T12-A16 WeakPolarHBondContact O-CB 3.33Å; T12-A16 PolarHBondContact O-N 3.03Å; V13-A16 WeakPolarHBondContact O-CB 3.43Å; V13-A16 PolarHBondContact O-N 2.85Å; L14-A16 VanDerWaalsContact C-N 3.31Å; L14-A16 PolarHBondContact O-N 2.88Å; A16-A19 WeakPolarHBondContact O-CB 3.49Å; A16-A19 PolarHBondContact O-N 3.12Å; A16-M20 WeakPolarHBondContact O-CG 3.44Å; A16-M20 PolarHBondContact O-N 2.82Å; A16-L42 HydrophobicContact CB-CB 4.1Å; A16-I62 HydrophobicContact CB-CD1 3.82Å; A16-I62 HydrophobicContact CB-CG1 4.11Å; A16-I62 HydrophobicContact CB-CG2 4.11Å
17S97.3Very high96.2Very high0 Ų020.6 Ų20.60%011%0.106CC..Hα-helixtrans-64.5-39.5176.8740000113.1V13 L14 L15 M20 Q21 W65 H69V13-S17 PolarHBondContact O-N 3.34Å; L14-S17 PolarHBondContact O-N 3.21Å; L14-S17 VanDerWaalsContact O-N 3.14Å; L14-S17 PolarHBondContact O-OG 3.4Å; L15-S17 PolarHBondContact O-N 3.17Å; S17-M20 PolarHBondContact O-N 3.01Å; S17-Q21 PolarHBondContact O-N 2.57Å; S17-W65 WeakPolarHBondContact OG-CB 3.27Å; S17-H69 PolarHBondContact OG-NE2 3.39Å
18Y97.6Very high96Very high12 Ų1221.4 Ų21.45%0.04711%0.112CC..Hα-helixtrans-66.3-37171.8-76.1-64.1000112.3L14 L15 M20 Q21 A22 H69 M72 A77 E80 I84L14-Y18 HydrophobicContact CD1-CD2 4.08Å; L14-Y18 HydrophobicContact CD1-CE2 3.54Å; L14-Y18 HydrophobicContact CD2-CE2 4.34Å; L14-Y18 HydrophobicContact CG-CD2 4.09Å; L14-Y18 HydrophobicContact CG-CE2 3.74Å; L14-Y18 WeakPolarHBondContact O-CD2 3.31Å; L14-Y18 PolarHBondContact O-N 3.39Å; L14-Y18 VanDerWaalsContact O-N 3.13Å; L15-Y18 PolarHBondContact O-N 2.95Å; Y18-M20 VanDerWaalsContact C-N 3.3Å; Y18-M20 PolarHBondContact O-N 2.95Å; Y18-Q21 PolarHBondContact O-N 3.48Å; Y18-A22 VanDerWaalsContact O-CB 3.28Å; Y18-A22 WeakPolarHBondContact O-CB 3.47Å; Y18-A22 PolarHBondContact O-N 2.99Å; Y18-H69 AromaticContact CD1-CE1 3.88Å; Y18-H69 AromaticContact CD1-NE2 3.79Å; Y18-H69 AromaticContact CE1-CE1 3.3Å; Y18-H69 WeakPolarHBondContact CE1-CE1 3.27Å; Y18-H69 AromaticContact CE1-ND1 3.47Å; Y18-H69 WeakPolarHBondContact CE1-ND1 3.41Å; Y18-H69 AromaticContact CE1-NE2 3.71Å; Y18-H69 AromaticContact CE2-CE1 3.91Å; Y18-H69 AromaticContact CZ-CE1 3.32Å; Y18-H69 AromaticContact CZ-ND1 3.87Å; Y18-H69 AromaticContact CZ-NE2 3.89Å; Y18-M72 HydrophobicContact CD1-SD 4.15Å; Y18-M72 HydrophobicContact CE1-CE 3.99Å; Y18-M72 HydrophobicContact CE1-SD 3.87Å; Y18-A77 HydrophobicContact CD1-CB 4.45Å; Y18-E80 HydrophobicContact CD1-CB 3.84Å; Y18-E80 HydrophobicContact CE1-CB 3.52Å; Y18-E80 HydrophobicContact CE1-CG 4.02Å; Y18-E80 HydrophobicContact CE2-CB 4.32Å; Y18-E80 HydrophobicContact CG-CB 4.37Å; Y18-I84 HydrophobicContact CD2-CD1 3.97Å; Y18-I84 HydrophobicContact CE2-CD1 3.42Å; Y18-I84 VanDerWaalsContact CE2-CD1 3.42Å
19A97.3Very high95.8Very high34 Ų3425.7 Ų25.728%0.28114%0.14SC..Hα-helixtrans-64-35.6174.100000112.1L15 A16 R23 Y81L15-A19 WeakPolarHBondContact O-CB 3.32Å; L15-A19 PolarHBondContact O-N 2.96Å; A16-A19 WeakPolarHBondContact O-CB 3.49Å; A16-A19 PolarHBondContact O-N 3.12Å; A19-R23 WeakPolarHBondContact O-CB 2.82Å; A19-R23 PolarHBondContact O-N 3.46Å; A19-Y81 HydrophobicContact CB-CD2 4.37Å; A19-Y81 HydrophobicContact CB-CE2 4.29Å
20M96.5Very high95.5Very high6 Ų632.8 Ų32.83%0.0317%0.173CC..Hα-helixtrans-70.1-44.2174.4-65.5-53.794.400112.1A16 S17 Y18 A22 R23 Y24 L37 E40 L42 I62 W66A16-M20 WeakPolarHBondContact O-CG 3.44Å; A16-M20 PolarHBondContact O-N 2.82Å; S17-M20 PolarHBondContact O-N 3.01Å; Y18-M20 VanDerWaalsContact C-N 3.3Å; Y18-M20 PolarHBondContact O-N 2.95Å; M20-A22 VanDerWaalsContact C-N 3.34Å; M20-A22 PolarHBondContact O-N 3.42Å; M20-R23 PolarHBondContact O-N 3.14Å; M20-Y24 WeakPolarHBondContact O-CB 3.48Å; M20-Y24 PolarHBondContact O-N 3.12Å; M20-Y24 HydrophobicContact SD-CD2 3.94Å; M20-Y24 HydrophobicContact SD-CE2 3.86Å; M20-L37 HydrophobicContact CG-CD1 4.1Å; M20-L37 HydrophobicContact CG-CD2 4.18Å; M20-L37 HydrophobicContact SD-CD1 4.29Å; M20-L37 HydrophobicContact SD-CD2 3.44Å; M20-L37 WeakPolarHBondContact SD-CD2 3.49Å; M20-E40 HydrophobicContact SD-CG 4.38Å; M20-L42 HydrophobicContact CE-CD2 3.48Å; M20-L42 VanDerWaalsContact CE-CD2 3.48Å; M20-L42 HydrophobicContact CG-CD2 4.19Å; M20-L42 HydrophobicContact SD-CD2 3.74Å; M20-I62 HydrophobicContact CG-CG2 4.37Å; M20-W66 HydrophobicContact CB-CD2 3.6Å; M20-W66 HydrophobicContact CB-CE3 3.78Å; M20-W66 HydrophobicContact CB-CG 3.96Å; M20-W66 HydrophobicContact CB-CZ2 4.38Å; M20-W66 HydrophobicContact CB-CZ3 4.22Å; M20-W66 HydrophobicContact CG-CE3 4.28Å
21Q97.1Very high95.3Very high0 Ų039.1 Ų39.10%020%0.204CC..Hα-helixtrans-60.2-42.6172.8-174.867.219.900111.9S17 Y18 R23 A25 D26 W66 H69 M72 A77S17-Q21 PolarHBondContact O-N 2.57Å; Y18-Q21 PolarHBondContact O-N 3.48Å; Q21-R23 VanDerWaalsContact C-N 3.32Å; Q21-R23 PolarHBondContact O-N 3.09Å; Q21-A25 WeakPolarHBondContact O-CA 3.46Å; Q21-A25 PolarHBondContact O-N 3.49Å; Q21-A25 PolarHBondContact OE1-O 2.88Å; Q21-A25 VanDerWaalsContact OE1-O 3.06Å; Q21-D26 PolarHBondContact NE2-OD1 3.3Å; Q21-W66 VanDerWaalsContact OE1-NE1 3.14Å; Q21-H69 HydrophobicContact CB-CB 4.01Å; Q21-H69 VanDerWaalsContact CD-O 3.28Å; Q21-H69 HydrophobicContact CG-CB 3.76Å; Q21-H69 PolarHBondContact NE2-O 3Å; Q21-M72 HydrophobicContact CG-CB 4.11Å; Q21-M72 PolarHBondContact NE2-O 3.2Å; Q21-A77 HydrophobicContact CB-CB 3.85Å; Q21-A77 HydrophobicContact CG-CB 3.74Å
22A96.5Very high95.1Very high19 Ų1939.9 Ų39.916%0.15721%0.207CC..Hα-helixtrans-61.9-38.1176.400000112.7Y18 M20 K74 A77 M78Y18-A22 VanDerWaalsContact O-CB 3.28Å; Y18-A22 WeakPolarHBondContact O-CB 3.47Å; Y18-A22 PolarHBondContact O-N 2.99Å; M20-A22 VanDerWaalsContact C-N 3.34Å; M20-A22 PolarHBondContact O-N 3.42Å; A22-K74 WeakPolarHBondContact O-CB 3.2Å; A22-K74 VanDerWaalsContact O-CD 3.23Å; A22-K74 WeakPolarHBondContact O-CD 3.36Å; A22-K74 VanDerWaalsContact O-CG 3.3Å; A22-K74 WeakPolarHBondContact O-CG 3.4Å; A22-A77 HydrophobicContact CB-CB 3.99Å; A22-M78 HydrophobicContact CB-CG 3.66Å
23R95.1Very high94.9Very high131 Ų13148.3 Ų48.349%0.49424%0.238SC..Hα-helixtrans-82.6-51.4-178.1-174.5164.3175.7-179.7-18.6112.9A19 M20 Q21 E40 K74A19-R23 WeakPolarHBondContact O-CB 2.82Å; A19-R23 PolarHBondContact O-N 3.46Å; M20-R23 PolarHBondContact O-N 3.14Å; Q21-R23 VanDerWaalsContact C-N 3.32Å; Q21-R23 PolarHBondContact O-N 3.09Å; R23-E40 IonicContact CZ-OE1 2.95Å; R23-E40 IonicContact CZ-OE2 2.67Å; R23-E40 IonicContact NE-OE1 2.68Å; R23-E40 IonicContact NH1-OE1 2.7Å; R23-E40 PolarHBondContact NH1-OE1 2.81Å; R23-E40 IonicContact NH1-OE2 3.79Å; R23-E40 PolarHBondContact NH1-OE2 3.35Å; R23-E40 IonicContact NH2-OE1 2.73Å; R23-E40 PolarHBondContact NH2-OE1 3.26Å; R23-E40 IonicContact NH2-OE2 3.09Å; R23-K74 PolarHBondContact O-NZ 3.41Å
24Y94.6Very high94.6Very high70 Ų7054.1 Ų54.128%0.27526%0.263SS..Hα-helixtrans-104.4-7.1-168.1-64.9-72.2000114.4M20 F36 E40 W66M20-Y24 WeakPolarHBondContact O-CB 3.48Å; M20-Y24 PolarHBondContact O-N 3.12Å; M20-Y24 HydrophobicContact SD-CD2 3.94Å; M20-Y24 HydrophobicContact SD-CE2 3.86Å; Y24-F36 HydrophobicContact CD1-CE1 4.11Å; Y24-F36 AromaticContact CD1-CZ 3.76Å; Y24-F36 HydrophobicContact CD1-CZ 3.76Å; Y24-F36 HydrophobicContact CD2-CE1 4.15Å; Y24-F36 HydrophobicContact CE1-CE1 4.11Å; Y24-F36 AromaticContact CE1-CZ 3.65Å; Y24-F36 HydrophobicContact CE1-CZ 3.65Å; Y24-F36 HydrophobicContact CE2-CE1 4.16Å; Y24-F36 HydrophobicContact CG-CE1 4.13Å; Y24-F36 HydrophobicContact CG-CZ 4.24Å; Y24-E40 PolarHBondContact OH-OE1 2.8Å; Y24-W66 HydrophobicContact CD2-CH2 4.37Å; Y24-W66 HydrophobicContact CG-CH2 4.34Å; Y24-W66 HydrophobicContact CG-CZ2 4.48Å
25A93.8Very high94.3Very high27 Ų2755.8 Ų55.822%0.22328%0.28CS..  trans59.1-154.2-166.500000111.6Q21 W66Q21-A25 WeakPolarHBondContact O-CA 3.46Å; Q21-A25 PolarHBondContact O-N 3.49Å; Q21-A25 PolarHBondContact OE1-O 2.88Å; Q21-A25 VanDerWaalsContact OE1-O 3.06Å; A25-W66 WeakPolarHBondContact O-CZ2 3.4Å; A25-W66 PolarHBondContact O-NE1 3.12Å
26D94.1Very high94Very high40 Ų4058.7 Ų58.721%0.21429%0.292CS..SBendtrans-56.5137-170.4-64.5-0.4000113.1Q21 S28 R70 C71 R210Q21-D26 PolarHBondContact NE2-OD1 3.3Å; D26-S28 PolarHBondContact O-N 2.64Å; D26-R70 HydrophobicContact CB-CG 4.24Å; D26-C71 PolarHBondContact OD1-N 2.77Å; D26-C71 PolarHBondContact OD2-N 2.81Å; D26-R210 IonicContact OD1-NH2 2.89Å
27F94.8Very high93.8Very high42 Ų4258.8 Ų58.818%0.18429%0.292CS..  trans-66123.2174177.8-104.7000111.9P29 H32 V63 W66F27-P29 HydrophobicContact CD1-CG 4.44Å; F27-P29 HydrophobicContact CE1-CB 4.43Å; F27-P29 HydrophobicContact CE1-CG 3.81Å; F27-P29 HydrophobicContact CZ-CG 4.45Å; F27-H32 HydrophobicContact CD2-CB 3.74Å; F27-H32 AromaticContact CD2-ND1 3.74Å; F27-H32 HydrophobicContact CE2-CB 3.5Å; F27-H32 WeakPolarHBondContact CE2-O 3.38Å; F27-V63 HydrophobicContact CD1-CG1 4.39Å; F27-V63 HydrophobicContact CD2-CG1 4.09Å; F27-V63 HydrophobicContact CE1-CG1 3.85Å; F27-V63 HydrophobicContact CE2-CG1 3.52Å; F27-V63 HydrophobicContact CE2-CG2 4.23Å; F27-V63 HydrophobicContact CG-CG1 4.5Å; F27-V63 HydrophobicContact CZ-CG1 3.4Å; F27-W66 HydrophobicContact CB-CD2 3.93Å; F27-W66 HydrophobicContact CB-CE3 4.4Å; F27-W66 HydrophobicContact CB-CG 4.17Å; F27-W66 HydrophobicContact CB-CZ2 4.29Å; F27-W66 HydrophobicContact CD2-CD2 4.12Å; F27-W66 AromaticContact CD2-CE3 3.71Å; F27-W66 HydrophobicContact CD2-CE3 3.71Å; F27-W66 HydrophobicContact CD2-CH2 4.11Å; F27-W66 HydrophobicContact CD2-CZ2 4.45Å; F27-W66 AromaticContact CD2-CZ3 3.73Å; F27-W66 HydrophobicContact CD2-CZ3 3.73Å; F27-W66 HydrophobicContact CE2-CZ3 4.4Å; F27-W66 HydrophobicContact CG-CD2 4.44Å; F27-W66 HydrophobicContact CG-CE3 4.45Å
28S92.7Very high93.3Very high28 Ų2863.6 Ų63.620%0.19632%0.321CS..  trans-116.7120.4168.6173.50000110.3D26 E30 M31 H32D26-S28 PolarHBondContact O-N 2.64Å; S28-E30 PolarHBondContact O-N 2.88Å; S28-E30 VanDerWaalsContact O-N 3.16Å; S28-M31 PolarHBondContact O-N 3.21Å; S28-H32 PolarHBondContact N-ND1 3.12Å; S28-H32 WeakPolarHBondContact O-CB 3.49Å; S28-H32 PolarHBondContact O-N 3.11Å
29P92Very high92.8Very high93 Ų9370.2 Ų70.260%0.60436%0.358SS*.THydrogen-bonded Turntrans-58.6-25.2177.5-24.232.5000114.8F27F27-P29 HydrophobicContact CD1-CG 4.44Å; F27-P29 HydrophobicContact CE1-CB 4.43Å; F27-P29 HydrophobicContact CE1-CG 3.81Å; F27-P29 HydrophobicContact CZ-CG 4.45Å
30E90.6Very high92.4Very high154 Ų15470.5 Ų70.572%0.7235%0.353SS*.THydrogen-bonded Turntrans-75.3-36.4-177.6-60-178.2164.300112.1S28 R33S28-E30 PolarHBondContact O-N 2.88Å; S28-E30 VanDerWaalsContact O-N 3.16Å; E30-R33 PolarHBondContact O-NE 3Å; E30-R33 VanDerWaalsContact O-NE 3.07Å
31M89.4Confident92.1Very high137 Ų13777.4 Ų77.468%0.67538%0.379SS*.THydrogen-bonded Turntrans-90-47.7179-54.4-171-155.500111.6S28 R33S28-M31 PolarHBondContact O-N 3.21Å; M31-R33 PolarHBondContact O-N 3.16Å
32H93.1Very high91.7Very high23 Ų2378.8 Ų78.811%0.10639%0.386CS..SBendtrans-96.266.8-173-50.7150.1000110.3F27 S28 F36 W66F27-H32 HydrophobicContact CD2-CB 3.74Å; F27-H32 AromaticContact CD2-ND1 3.74Å; F27-H32 HydrophobicContact CE2-CB 3.5Å; F27-H32 WeakPolarHBondContact CE2-O 3.38Å; S28-H32 PolarHBondContact N-ND1 3.12Å; S28-H32 WeakPolarHBondContact O-CB 3.49Å; S28-H32 PolarHBondContact O-N 3.11Å; H32-F36 HydrophobicContact CB-CD1 4.02Å; H32-F36 HydrophobicContact CB-CE1 4.36Å; H32-F36 HydrophobicContact CB-CG 4.25Å; H32-F36 AromaticContact CD2-CE1 3.56Å; H32-F36 AromaticContact CD2-CE2 3.78Å; H32-F36 AromaticContact CD2-CZ 3.4Å; H32-F36 WeakPolarHBondContact CD2-CZ 3.45Å; H32-F36 AromaticContact CG-CE1 3.99Å; H32-F36 AromaticContact NE2-CZ 3.91Å; H32-W66 HydrophobicContact CB-CH2 4.25Å; H32-W66 HydrophobicContact CB-CZ3 4.37Å; H32-W66 AromaticContact CE1-CH2 3.5Å; H32-W66 AromaticContact CE1-CZ2 3.59Å; H32-W66 AromaticContact CG-CH2 3.64Å; H32-W66 AromaticContact ND1-CH2 3.15Å; H32-W66 WeakPolarHBondContact ND1-CH2 3.47Å; H32-W66 AromaticContact ND1-CZ2 3.51Å; H32-W66 AromaticContact ND1-CZ3 3.98Å
33R91.2Very high91.6Very high185 Ų18578.6 Ų78.670%0.69838%0.382SS*.  trans-70.2161.1179.2-54.4-179.8-168.9179.32.9110.8E30 M31 G35 F36E30-R33 PolarHBondContact O-NE 3Å; E30-R33 VanDerWaalsContact O-NE 3.07Å; M31-R33 PolarHBondContact O-N 3.16Å; R33-G35 PolarHBondContact O-N 2.86Å; R33-F36 WeakPolarHBondContact O-CB 3.38Å; R33-F36 PolarHBondContact O-N 2.67Å
34K90.6Very high91.6Very high123 Ų12372.6 Ų72.654%0.53536%0.36SS..THydrogen-bonded Turntrans-50.5137.2173.7-80.3-175.7164.9-96.60111.4E56 D60K34-E56 WeakPolarHBondContact CD-OE1 3.41Å; K34-E56 IonicContact NZ-OE1 2.7Å; K34-E56 PolarHBondContact NZ-OE1 2.8Å; K34-D60 WeakPolarHBondContact CE-OD1 3.47Å; K34-D60 IonicContact NZ-OD1 2.8Å; K34-D60 PolarHBondContact NZ-OD1 2.83Å; K34-D60 IonicContact NZ-OD2 3.57Å; K34-D60 PolarHBondContact NZ-OD2 3.46Å
35G91.1Very high91.5Very high34 Ų3474 Ų7435%0.35137%0.369SS..THydrogen-bonded Turntrans86.2-3.6-172.400000114.9R33 L37 T38 E59R33-G35 PolarHBondContact O-N 2.86Å; G35-L37 VanDerWaalsContact C-N 3.26Å; G35-L37 PolarHBondContact O-N 2.95Å; G35-T38 WeakPolarHBondContact CA-OG1 3.22Å; G35-T38 WeakPolarHBondContact O-CB 2.91Å; G35-T38 PolarHBondContact O-N 2.93Å; G35-T38 PolarHBondContact O-OG1 2.91Å; G35-E59 WeakPolarHBondContact CA-OE2 3.15Å; G35-E59 PolarHBondContact N-OE1 3.38Å; G35-E59 PolarHBondContact N-OE2 2.92Å
36F92Very high91.6Very high70 Ų7073.9 Ų73.931%0.30736%0.363SS..THydrogen-bonded Turntrans-59.5-35.8177.6178.1-103.3000112.5Y24 H32 R33 E59 W66Y24-F36 HydrophobicContact CD1-CE1 4.11Å; Y24-F36 AromaticContact CD1-CZ 3.76Å; Y24-F36 HydrophobicContact CD1-CZ 3.76Å; Y24-F36 HydrophobicContact CD2-CE1 4.15Å; Y24-F36 HydrophobicContact CE1-CE1 4.11Å; Y24-F36 AromaticContact CE1-CZ 3.65Å; Y24-F36 HydrophobicContact CE1-CZ 3.65Å; Y24-F36 HydrophobicContact CE2-CE1 4.16Å; Y24-F36 HydrophobicContact CG-CE1 4.13Å; Y24-F36 HydrophobicContact CG-CZ 4.24Å; H32-F36 HydrophobicContact CB-CD1 4.02Å; H32-F36 HydrophobicContact CB-CE1 4.36Å; H32-F36 HydrophobicContact CB-CG 4.25Å; H32-F36 AromaticContact CD2-CE1 3.56Å; H32-F36 AromaticContact CD2-CE2 3.78Å; H32-F36 AromaticContact CD2-CZ 3.4Å; H32-F36 WeakPolarHBondContact CD2-CZ 3.45Å; H32-F36 AromaticContact CG-CE1 3.99Å; H32-F36 AromaticContact NE2-CZ 3.91Å; R33-F36 WeakPolarHBondContact O-CB 3.38Å; R33-F36 PolarHBondContact O-N 2.67Å; F36-E59 PolarHBondContact N-OE1 2.86Å; F36-E59 VanDerWaalsContact N-OE1 3.09Å; F36-W66 HydrophobicContact CD1-CH2 4.45Å; F36-W66 HydrophobicContact CD1-CZ3 4.38Å; F36-W66 AromaticContact CE1-CH2 4Å; F36-W66 HydrophobicContact CE1-CH2 4Å; F36-W66 HydrophobicContact CE1-CZ3 4.35Å
37L92.3Very high91.7Very high6 Ų672 Ų723%0.03135%0.353CS..THydrogen-bonded Turntrans-88.23179.9-56.7-172.6000114.4M20 G35 N39 E40 L42 E59 I62 V63 W66M20-L37 HydrophobicContact CG-CD1 4.1Å; M20-L37 HydrophobicContact CG-CD2 4.18Å; M20-L37 HydrophobicContact SD-CD1 4.29Å; M20-L37 HydrophobicContact SD-CD2 3.44Å; M20-L37 WeakPolarHBondContact SD-CD2 3.49Å; G35-L37 VanDerWaalsContact C-N 3.26Å; G35-L37 PolarHBondContact O-N 2.95Å; L37-N39 PolarHBondContact O-N 3.49Å; L37-N39 VanDerWaalsContact O-N 3.09Å; L37-E40 HydrophobicContact CD2-CG 4.37Å; L37-E40 WeakPolarHBondContact O-CB 3.44Å; L37-E40 PolarHBondContact O-N 2.87Å; L37-L42 HydrophobicContact CB-CD1 4.05Å; L37-L42 HydrophobicContact CD1-CD1 4.01Å; L37-E59 HydrophobicContact CB-CG 4.12Å; L37-E59 WeakPolarHBondContact CB-OE1 3.37Å; L37-E59 HydrophobicContact CD1-CG 4.2Å; L37-E59 HydrophobicContact CG-CG 4.24Å; L37-E59 PolarHBondContact N-OE1 3.3Å; L37-I62 HydrophobicContact CD1-CG2 4.17Å; L37-V63 HydrophobicContact CD1-CG2 4.19Å; L37-W66 HydrophobicContact CD2-CZ3 4.23Å
38T88Confident91.6Very high101 Ų10175.4 Ų75.462%0.6236%0.364SS*.THydrogen-bonded Turntrans-52.3-35.7-177.5-54.30000114.1G35G35-T38 WeakPolarHBondContact CA-OG1 3.22Å; G35-T38 WeakPolarHBondContact O-CB 2.91Å; G35-T38 PolarHBondContact O-N 2.93Å; G35-T38 PolarHBondContact O-OG1 2.91Å
39N86.2Confident91.6Very high152 Ų15278.7 Ų78.781%0.81338%0.377SS*.THydrogen-bonded Turntrans-91.2-3.1-177.6-65.7-43.9000113.6L37L37-N39 PolarHBondContact O-N 3.49Å; L37-N39 VanDerWaalsContact O-N 3.09Å
40E89.8Confident91.7Very high40 Ų4074.4 Ų74.419%0.18735%0.349CS..  trans-89.2131.4-176.2-73.6-59.3130.300112.4M20 R23 Y24 L37 L42M20-E40 HydrophobicContact SD-CG 4.38Å; R23-E40 IonicContact CZ-OE1 2.95Å; R23-E40 IonicContact CZ-OE2 2.67Å; R23-E40 IonicContact NE-OE1 2.68Å; R23-E40 IonicContact NH1-OE1 2.7Å; R23-E40 PolarHBondContact NH1-OE1 2.81Å; R23-E40 IonicContact NH1-OE2 3.79Å; R23-E40 PolarHBondContact NH1-OE2 3.35Å; R23-E40 IonicContact NH2-OE1 2.73Å; R23-E40 PolarHBondContact NH2-OE1 3.26Å; R23-E40 IonicContact NH2-OE2 3.09Å; Y24-E40 PolarHBondContact OH-OE1 2.8Å; L37-E40 HydrophobicContact CD2-CG 4.37Å; L37-E40 WeakPolarHBondContact O-CB 3.44Å; L37-E40 PolarHBondContact O-N 2.87Å; E40-L42 VanDerWaalsContact C-N 3.34Å; E40-L42 HydrophobicContact CB-CD2 3.69Å; E40-L42 HydrophobicContact CB-CG 3.95Å; E40-L42 PolarHBondContact O-N 2.83Å
41R90.2Very high91.9Very high150 Ų15067.5 Ų67.557%0.56632%0.316SS*.  trans-81.383.5172.6-170.7-179.8175.7166.70.5109.4M1M1-R41 PolarHBondContact O-NH2 2.88Å; M1-R41 HydrophobicContact SD-CB 3.88Å; M1-R41 HydrophobicContact SD-CG 3.64Å
42L87.5Confident92.1Very high30 Ų3066.9 Ų66.916%0.15731%0.31CS..  trans-80.9-30.6-174.3-58.3173.4000114A16 M20 L37 E40 I62A16-L42 HydrophobicContact CB-CB 4.1Å; M20-L42 HydrophobicContact CE-CD2 3.48Å; M20-L42 VanDerWaalsContact CE-CD2 3.48Å; M20-L42 HydrophobicContact CG-CD2 4.19Å; M20-L42 HydrophobicContact SD-CD2 3.74Å; L37-L42 HydrophobicContact CB-CD1 4.05Å; L37-L42 HydrophobicContact CD1-CD1 4.01Å; E40-L42 VanDerWaalsContact C-N 3.34Å; E40-L42 HydrophobicContact CB-CD2 3.69Å; E40-L42 HydrophobicContact CB-CG 3.95Å; E40-L42 PolarHBondContact O-N 2.83Å; L42-I62 HydrophobicContact CB-CD1 3.94Å; L42-I62 HydrophobicContact CD1-CD1 3.48Å; L42-I62 VanDerWaalsContact CD1-CD1 3.48Å; L42-I62 HydrophobicContact CG-CD1 4.27Å
43M93.7Very high92.1Very high15 Ų1567 Ų677%0.07431%0.311CS..SBendtrans-141.9159.3-167.460.6-174.268.300113.5T12 V47 R48 W58 I62T12-M43 HydrophobicContact CG2-CB 3.58Å; M43-V47 HydrophobicContact CB-CB 4.48Å; M43-V47 HydrophobicContact SD-CG1 4.31Å; M43-R48 HydrophobicContact CG-CB 4.42Å; M43-R48 HydrophobicContact SD-CB 4.05Å; M43-R48 HydrophobicContact SD-CG 4.16Å; M43-W58 HydrophobicContact CE-CB 3.89Å; M43-W58 HydrophobicContact CE-CD2 3.65Å; M43-W58 HydrophobicContact CE-CE3 3.76Å; M43-W58 HydrophobicContact CE-CG 3.76Å; M43-W58 HydrophobicContact CE-CZ3 4.45Å; M43-W58 HydrophobicContact SD-CD2 4.02Å; M43-W58 HydrophobicContact SD-CE3 4.47Å; M43-W58 HydrophobicContact SD-CG 4.21Å; M43-W58 HydrophobicContact SD-CZ2 4.43Å; M43-I62 HydrophobicContact CE-CD1 3.88Å
44P95.1Very high92.1Very high4 Ų460.7 Ų60.73%0.02630%0.295CS..  trans-61.8153.7167.1-16.630.9000112.1D3 R46 V47 R48D3-P44 HydrophobicContact CB-CB 4.16Å; D3-P44 VanDerWaalsContact OD1-CB 3.29Å; D3-P44 WeakPolarHBondContact OD1-CB 3.39Å; D3-P44 WeakPolarHBondContact OD1-CG 3.29Å; P44-R46 VanDerWaalsContact C-N 3.33Å; P44-R46 PolarHBondContact O-N 2.75Å; P44-V47 HydrophobicContact CB-CG2 4.37Å; P44-V47 HydrophobicContact CG-CG2 4.15Å; P44-V47 PolarHBondContact O-N 3.15Å; P44-R48 PolarHBondContact O-N 2.93Å
45E93.4Very high92.2Very high101 Ų10158.8 Ų58.847%0.47230%0.302SS..Hα-helixtrans-58.2-44.5177-156.9112.9-99.400111.8V47 R48 E49E45-V47 VanDerWaalsContact C-N 3.29Å; E45-V47 PolarHBondContact O-N 2.9Å; E45-R48 WeakPolarHBondContact O-CA 3.4Å; E45-R48 WeakPolarHBondContact O-CB 3.39Å; E45-R48 PolarHBondContact O-N 2.84Å; E45-R48 IonicContact OE1-CZ 3.48Å; E45-R48 IonicContact OE1-NH1 3.69Å; E45-R48 PolarHBondContact OE1-NH1 2.71Å; E45-R48 IonicContact OE1-NH2 3.99Å; E45-R48 PolarHBondContact OE1-NH2 2.86Å; E45-E49 PolarHBondContact O-N 2.97Å
46R95.5Very high92.2Very high23 Ų2362 Ų629%0.08731%0.309CS..Hα-helixtrans-47.6-48.3173.6173.9-178.852.981.211.1112.6D3 C7 P44 R48 E49 Q50 T427 D430D3-R46 IonicContact OD1-CZ 3.14Å; D3-R46 IonicContact OD1-NE 2.71Å; D3-R46 IonicContact OD1-NH2 3.99Å; D3-R46 PolarHBondContact OD1-NH2 3.42Å; D3-R46 IonicContact OD2-CZ 3.13Å; D3-R46 IonicContact OD2-NE 2.67Å; D3-R46 PolarHBondContact OD2-NE 2.56Å; D3-R46 IonicContact OD2-NH2 2.64Å; C7-R46 PolarHBondContact O-NH1 2.99Å; C7-R46 PolarHBondContact O-NH2 3.14Å; P44-R46 VanDerWaalsContact C-N 3.33Å; P44-R46 PolarHBondContact O-N 2.75Å; R46-R48 VanDerWaalsContact C-N 3.34Å; R46-E49 PolarHBondContact O-N 3.26Å; R46-Q50 VanDerWaalsContact O-CB 3.31Å; R46-Q50 WeakPolarHBondContact O-CB 3.48Å; R46-Q50 VanDerWaalsContact O-CG 3.23Å; R46-Q50 WeakPolarHBondContact O-CG 3.44Å; R46-Q50 PolarHBondContact O-N 3.42Å; R46-Q50 VanDerWaalsContact O-N 3.09Å; R46-T427 HydrophobicContact CG-CG2 3.88Å; R46-D430 IonicContact CZ-OD1 2.8Å; R46-D430 IonicContact NH1-OD1 3.92Å; R46-D430 PolarHBondContact NH1-OD1 3.49Å
47V95.7Very high92.3Very high0 Ų062.7 Ų62.70%031%0.313CS..Hα-helixtrans-68.5-36.6-178.7177.80000110.9P9 T12 M43 P44 E45 Y51 W58P9-V47 HydrophobicContact CB-CG1 3.99Å; P9-V47 HydrophobicContact CG-CG1 4.46Å; T12-V47 HydrophobicContact CG2-CG1 4.3Å; T12-V47 HydrophobicContact CG2-CG2 4.38Å; M43-V47 HydrophobicContact CB-CB 4.48Å; M43-V47 HydrophobicContact SD-CG1 4.31Å; P44-V47 HydrophobicContact CB-CG2 4.37Å; P44-V47 HydrophobicContact CG-CG2 4.15Å; P44-V47 PolarHBondContact O-N 3.15Å; E45-V47 VanDerWaalsContact C-N 3.29Å; E45-V47 PolarHBondContact O-N 2.9Å; V47-Y51 WeakPolarHBondContact O-CD2 3.29Å; V47-W58 HydrophobicContact CG1-CH2 3.94Å; V47-W58 HydrophobicContact CG1-CZ2 4.24Å; V47-W58 WeakPolarHBondContact O-CZ2 3.1Å
48R92.8Very high92.4Very high114 Ų11462.8 Ų62.843%0.4331%0.312SS..Hα-helixtrans-68.7-41.1177.5-154.5-162.9-45.2122.311.3112.3M43 P44 E45 R46M43-R48 HydrophobicContact CG-CB 4.42Å; M43-R48 HydrophobicContact SD-CB 4.05Å; M43-R48 HydrophobicContact SD-CG 4.16Å; P44-R48 PolarHBondContact O-N 2.93Å; E45-R48 WeakPolarHBondContact O-CA 3.4Å; E45-R48 WeakPolarHBondContact O-CB 3.39Å; E45-R48 PolarHBondContact O-N 2.84Å; E45-R48 IonicContact OE1-CZ 3.48Å; E45-R48 IonicContact OE1-NH1 3.69Å; E45-R48 PolarHBondContact OE1-NH1 2.71Å; E45-R48 IonicContact OE1-NH2 3.99Å; E45-R48 PolarHBondContact OE1-NH2 2.86Å; R46-R48 VanDerWaalsContact C-N 3.34Å
49E92.5Very high92.8Very high98 Ų9858.5 Ų58.546%0.45829%0.286SS..Hα-helixtrans-77.1-23.7-178.7-72.6-167-156.900114.2E45 R46 Y51 K425E45-E49 PolarHBondContact O-N 2.97Å; R46-E49 PolarHBondContact O-N 3.26Å; E49-Y51 VanDerWaalsContact C-N 3.29Å; E49-Y51 PolarHBondContact O-N 2.74Å; E49-K425 HydrophobicContact CB-CD 4.45Å; E49-K425 IonicContact OE2-NZ 3.58Å; E49-K425 PolarHBondContact OE2-NZ 3.26Å
50Q94.7Very high93.2Very high2 Ų254.6 Ų54.61%0.00926%0.264CS..THydrogen-bonded Turntrans-76.3-8.3-175.8-86.7179.3600115.4R46 R421 D422 K425 D430R46-Q50 VanDerWaalsContact O-CB 3.31Å; R46-Q50 WeakPolarHBondContact O-CB 3.48Å; R46-Q50 VanDerWaalsContact O-CG 3.23Å; R46-Q50 WeakPolarHBondContact O-CG 3.44Å; R46-Q50 PolarHBondContact O-N 3.42Å; R46-Q50 VanDerWaalsContact O-N 3.09Å; Q50-R421 CarbonylContact O-C 3.52Å; Q50-R421 WeakPolarHBondContact O-CA 3.23Å; Q50-R421 WeakPolarHBondContact O-CG 3.4Å; Q50-D422 PolarHBondContact O-N 3.01Å; Q50-K425 HydrophobicContact CB-CB 4.48Å; Q50-K425 HydrophobicContact CG-CB 3.79Å; Q50-K425 VanDerWaalsContact CG-O 3.22Å; Q50-K425 WeakPolarHBondContact CG-O 3.42Å; Q50-K425 PolarHBondContact NE2-O 3.34Å; Q50-D430 PolarHBondContact NE2-OD2 2.92Å; Q50-D430 PolarHBondContact OE1-OD1 3.47Å
51Y94.6Very high93.4Very high9 Ų954.6 Ų54.64%0.03526%0.264CS..BIsolated β-bridgetrans-135138.5-173.8-63.4-87.2000111.4P9 V47 E49 L53 W58 L417 M420 R421P9-Y51 HydrophobicContact CB-CE2 3.75Å; P9-Y51 HydrophobicContact CG-CE2 3.6Å; P9-Y51 WeakPolarHBondContact CG-OH 2.96Å; V47-Y51 WeakPolarHBondContact O-CD2 3.29Å; E49-Y51 VanDerWaalsContact C-N 3.29Å; E49-Y51 PolarHBondContact O-N 2.74Å; Y51-L53 PolarHBondContact O-N 3Å; Y51-W58 HydrophobicContact CD2-CH2 4.05Å; Y51-W58 AromaticContact CD2-CZ2 3.9Å; Y51-W58 HydrophobicContact CD2-CZ2 3.9Å; Y51-W58 HydrophobicContact CG-CH2 4.35Å; Y51-W58 HydrophobicContact CG-CZ2 4.11Å; Y51-L417 HydrophobicContact CD1-CB 4.12Å; Y51-L417 WeakPolarHBondContact CD1-O 3.37Å; Y51-L417 VanDerWaalsContact CE1-C 3.45Å; Y51-L417 HydrophobicContact CE1-CB 3.72Å; Y51-L417 WeakPolarHBondContact CE1-O 3.33Å; Y51-M420 WeakPolarHBondContact CA-O 3.36Å; Y51-R421 HydrophobicContact CD1-CB 3.91Å; Y51-R421 HydrophobicContact CD1-CG 4.14Å; Y51-R421 HydrophobicContact CE1-CB 3.58Å; Y51-R421 HydrophobicContact CE1-CG 3.6Å; Y51-R421 PolarHBondContact OH-NE 3Å
52K93.4Very high93.7Very high124 Ų12447.5 Ų47.554%0.53924%0.237SC..  trans-80.257.6-179.5-68.3169.3178.2158.90110.3M420 D422K52-M420 HydrophobicContact CB-CE 4.29Å; K52-M420 PolarHBondContact N-O 2.83Å; K52-M420 WeakPolarHBondContact O-CE 3.42Å; K52-D422 VanDerWaalsContact CE-CG 3.41Å; K52-D422 WeakPolarHBondContact CE-OD2 3.46Å; K52-D422 IonicContact NZ-OD1 3.88Å; K52-D422 PolarHBondContact NZ-OD1 3.48Å; K52-D422 IonicContact NZ-OD2 3.83Å; K52-D422 PolarHBondContact NZ-OD2 3.33Å
53L93.2Very high94.1Very high25 Ų2547.3 Ų47.313%0.13124%0.237CC..  trans-122.7136.1-177.1-66.7175.2000110.2Y51 Q57 W58 K61 L417 M420Y51-L53 PolarHBondContact O-N 3Å; L53-Q57 HydrophobicContact CB-CB 4.28Å; L53-Q57 HydrophobicContact CD2-CB 4.12Å; L53-W58 HydrophobicContact CB-CG 4.49Å; L53-W58 HydrophobicContact CD1-CD2 4.14Å; L53-W58 HydrophobicContact CD1-CE3 4.35Å; L53-W58 HydrophobicContact CD1-CH2 4.18Å; L53-W58 HydrophobicContact CD1-CZ2 3.96Å; L53-W58 HydrophobicContact CD1-CZ3 4.36Å; L53-K61 HydrophobicContact CD1-CD 4.3Å; L53-L417 HydrophobicContact CD1-CD2 3.72Å; L53-M420 HydrophobicContact CD2-CB 4.28Å; L53-M420 HydrophobicContact CD2-CE 4.45Å; L53-M420 HydrophobicContact CD2-CG 4.07Å; L53-M420 HydrophobicContact CG-CB 4.3Å
54S92.3Very high94.2Very high53 Ų5349 Ų4937%0.37125%0.254SS..  trans-70.8164.3172.478.30000111.7E56 Q57 W58S54-E56 PolarHBondContact O-N 2.9Å; S54-E56 PolarHBondContact OG-N 2.79Å; S54-Q57 PolarHBondContact O-N 2.72Å; S54-Q57 VanDerWaalsContact O-N 3.16Å; S54-Q57 WeakPolarHBondContact OG-CG 3.43Å; S54-Q57 PolarHBondContact OG-N 3.4Å; S54-Q57 VanDerWaalsContact OG-N 3.07Å; S54-W58 PolarHBondContact O-N 3.49Å
55A91.3Very high94.3Very high83 Ų8349.6 Ų49.669%0.68626%0.256SS*.Hα-helixtrans-57.8-37.2172.600000112.1W58 E59A55-W58 PolarHBondContact O-N 3.23Å; A55-E59 WeakPolarHBondContact O-CB 3.25Å; A55-E59 PolarHBondContact O-N 2.91Å
56E92.3Very high94.4Very high103 Ų10344.8 Ų44.848%0.48123%0.233SC..Hα-helixtrans-66.3-40175.5-171.2-172169.900112.2K34 S54 W58 E59 D60K34-E56 WeakPolarHBondContact CD-OE1 3.41Å; K34-E56 IonicContact NZ-OE1 2.7Å; K34-E56 PolarHBondContact NZ-OE1 2.8Å; S54-E56 PolarHBondContact O-N 2.9Å; S54-E56 PolarHBondContact OG-N 2.79Å; E56-W58 VanDerWaalsContact C-N 3.3Å; E56-W58 PolarHBondContact O-N 3.34Å; E56-E59 PolarHBondContact O-N 3.01Å; E56-D60 PolarHBondContact O-N 2.89Å
57Q94Very high94.4Very high84 Ų8446.4 Ų46.439%0.39325%0.248SC..Hα-helixtrans-69-29.7176.1-70.9173.9-53.600112.5L53 S54 K61L53-Q57 HydrophobicContact CB-CB 4.28Å; L53-Q57 HydrophobicContact CD2-CB 4.12Å; S54-Q57 PolarHBondContact O-N 2.72Å; S54-Q57 VanDerWaalsContact O-N 3.16Å; S54-Q57 WeakPolarHBondContact OG-CG 3.43Å; S54-Q57 PolarHBondContact OG-N 3.4Å; S54-Q57 VanDerWaalsContact OG-N 3.07Å; Q57-K61 VanDerWaalsContact O-CG 3.32Å; Q57-K61 WeakPolarHBondContact O-CG 3.17Å; Q57-K61 PolarHBondContact O-N 3.26Å
58W94.8Very high94.3Very high7 Ų751.1 Ų51.13%0.02727%0.27CS..Hα-helixtrans-72.5-40.4169.4-79.9119.9000112.2V13 M43 V47 Y51 L53 S54 A55 E56 K61 I62 L417V13-W58 HydrophobicContact CG2-CE3 4.02Å; V13-W58 HydrophobicContact CG2-CZ3 3.58Å; M43-W58 HydrophobicContact CE-CB 3.89Å; M43-W58 HydrophobicContact CE-CD2 3.65Å; M43-W58 HydrophobicContact CE-CE3 3.76Å; M43-W58 HydrophobicContact CE-CG 3.76Å; M43-W58 HydrophobicContact CE-CZ3 4.45Å; M43-W58 HydrophobicContact SD-CD2 4.02Å; M43-W58 HydrophobicContact SD-CE3 4.47Å; M43-W58 HydrophobicContact SD-CG 4.21Å; M43-W58 HydrophobicContact SD-CZ2 4.43Å; V47-W58 HydrophobicContact CG1-CH2 3.94Å; V47-W58 HydrophobicContact CG1-CZ2 4.24Å; V47-W58 WeakPolarHBondContact O-CZ2 3.1Å; Y51-W58 HydrophobicContact CD2-CH2 4.05Å; Y51-W58 AromaticContact CD2-CZ2 3.9Å; Y51-W58 HydrophobicContact CD2-CZ2 3.9Å; Y51-W58 HydrophobicContact CG-CH2 4.35Å; Y51-W58 HydrophobicContact CG-CZ2 4.11Å; L53-W58 HydrophobicContact CB-CG 4.49Å; L53-W58 HydrophobicContact CD1-CD2 4.14Å; L53-W58 HydrophobicContact CD1-CE3 4.35Å; L53-W58 HydrophobicContact CD1-CH2 4.18Å; L53-W58 HydrophobicContact CD1-CZ2 3.96Å; L53-W58 HydrophobicContact CD1-CZ3 4.36Å; S54-W58 PolarHBondContact O-N 3.49Å; A55-W58 PolarHBondContact O-N 3.23Å; E56-W58 VanDerWaalsContact C-N 3.3Å; E56-W58 PolarHBondContact O-N 3.34Å; W58-K61 HydrophobicContact CE3-CD 4.47Å; W58-K61 PolarHBondContact O-N 3.49Å; W58-I62 WeakPolarHBondContact O-CG1 3.22Å; W58-I62 PolarHBondContact O-N 3.39Å; W58-L417 HydrophobicContact CH2-CD1 4.39Å; W58-L417 HydrophobicContact CH2-CD2 3.74Å; W58-L417 HydrophobicContact CZ3-CD1 4.37Å; W58-L417 HydrophobicContact CZ3-CD2 3.71Å
59E94.9Very high94.4Very high12 Ų1246.2 Ų46.26%0.05625%0.252CS..Hα-helixtrans-59.7-51.1173.4179172.5-141.100111G35 F36 L37 A55 E56 K61 I62 V63G35-E59 WeakPolarHBondContact CA-OE2 3.15Å; G35-E59 PolarHBondContact N-OE1 3.38Å; G35-E59 PolarHBondContact N-OE2 2.92Å; F36-E59 PolarHBondContact N-OE1 2.86Å; F36-E59 VanDerWaalsContact N-OE1 3.09Å; L37-E59 HydrophobicContact CB-CG 4.12Å; L37-E59 WeakPolarHBondContact CB-OE1 3.37Å; L37-E59 HydrophobicContact CD1-CG 4.2Å; L37-E59 HydrophobicContact CG-CG 4.24Å; L37-E59 PolarHBondContact N-OE1 3.3Å; A55-E59 WeakPolarHBondContact O-CB 3.25Å; A55-E59 PolarHBondContact O-N 2.91Å; E56-E59 PolarHBondContact O-N 3.01Å; E59-K61 VanDerWaalsContact C-N 3.28Å; E59-K61 PolarHBondContact O-N 3.35Å; E59-I62 PolarHBondContact O-N 3.3Å; E59-V63 HydrophobicContact CG-CG2 4.02Å; E59-V63 WeakPolarHBondContact O-CB 3.34Å; E59-V63 VanDerWaalsContact O-CG2 3.31Å; E59-V63 WeakPolarHBondContact O-CG2 3.46Å; E59-V63 PolarHBondContact O-N 2.69Å
60D94.8Very high94.3Very high69 Ų6950.3 Ų50.337%0.36926%0.263SS..Hα-helixtrans-55.3-41.5177.3-76.3-15.5000112K34 E56 A64K34-D60 WeakPolarHBondContact CE-OD1 3.47Å; K34-D60 IonicContact NZ-OD1 2.8Å; K34-D60 PolarHBondContact NZ-OD1 2.83Å; K34-D60 IonicContact NZ-OD2 3.57Å; K34-D60 PolarHBondContact NZ-OD2 3.46Å; E56-D60 PolarHBondContact O-N 2.89Å; D60-A64 WeakPolarHBondContact O-CB 3.42Å; D60-A64 PolarHBondContact O-N 2.88Å
61K95.2Very high94Very high41 Ų4153.6 Ų53.618%0.17829%0.286CS..Hα-helixtrans-66.6-37.9176.2-76176.7-177.5-62.20112.9L53 Q57 W58 E59 L413 D416 L417L53-K61 HydrophobicContact CD1-CD 4.3Å; Q57-K61 VanDerWaalsContact O-CG 3.32Å; Q57-K61 WeakPolarHBondContact O-CG 3.17Å; Q57-K61 PolarHBondContact O-N 3.26Å; W58-K61 HydrophobicContact CE3-CD 4.47Å; W58-K61 PolarHBondContact O-N 3.49Å; E59-K61 VanDerWaalsContact C-N 3.28Å; E59-K61 PolarHBondContact O-N 3.35Å; K61-L413 HydrophobicContact CD-CD1 4.49Å; K61-D416 IonicContact NZ-OD2 3.65Å; K61-D416 PolarHBondContact NZ-OD2 2.69Å; K61-L417 HydrophobicContact CD-CD2 4.04Å
62I96.5Very high93.9Very high0 Ų055.3 Ų55.30%030%0.295CS..Hα-helixtrans-76.3-39.5179.2-69.2166.8000111V13 A16 M20 L37 L42 M43 W58 E59 A64 W65 W66V13-I62 HydrophobicContact CG1-CG1 3.96Å; A16-I62 HydrophobicContact CB-CD1 3.82Å; A16-I62 HydrophobicContact CB-CG1 4.11Å; A16-I62 HydrophobicContact CB-CG2 4.11Å; M20-I62 HydrophobicContact CG-CG2 4.37Å; L37-I62 HydrophobicContact CD1-CG2 4.17Å; L42-I62 HydrophobicContact CB-CD1 3.94Å; L42-I62 HydrophobicContact CD1-CD1 3.48Å; L42-I62 VanDerWaalsContact CD1-CD1 3.48Å; L42-I62 HydrophobicContact CG-CD1 4.27Å; M43-I62 HydrophobicContact CE-CD1 3.88Å; W58-I62 WeakPolarHBondContact O-CG1 3.22Å; W58-I62 PolarHBondContact O-N 3.39Å; E59-I62 PolarHBondContact O-N 3.3Å; I62-A64 VanDerWaalsContact C-N 3.35Å; I62-W65 PolarHBondContact O-N 3.17Å; I62-W66 WeakPolarHBondContact O-CB 3.17Å; I62-W66 PolarHBondContact O-N 3.45Å
63V96.1Very high93.8Very high26 Ų2650.7 Ų50.716%0.15828%0.275CS..Hα-helixtrans-63.4-38.9176.1167.10000111.4F27 L37 E59 W65 W66 S67F27-V63 HydrophobicContact CD1-CG1 4.39Å; F27-V63 HydrophobicContact CD2-CG1 4.09Å; F27-V63 HydrophobicContact CE1-CG1 3.85Å; F27-V63 HydrophobicContact CE2-CG1 3.52Å; F27-V63 HydrophobicContact CE2-CG2 4.23Å; F27-V63 HydrophobicContact CG-CG1 4.5Å; F27-V63 HydrophobicContact CZ-CG1 3.4Å; L37-V63 HydrophobicContact CD1-CG2 4.19Å; E59-V63 HydrophobicContact CG-CG2 4.02Å; E59-V63 WeakPolarHBondContact O-CB 3.34Å; E59-V63 VanDerWaalsContact O-CG2 3.31Å; E59-V63 WeakPolarHBondContact O-CG2 3.46Å; E59-V63 PolarHBondContact O-N 2.69Å; V63-W65 PolarHBondContact O-N 2.98Å; V63-W66 HydrophobicContact CG2-CE3 4.38Å; V63-W66 PolarHBondContact O-N 3.27Å; V63-S67 WeakPolarHBondContact O-CB 3.31Å; V63-S67 PolarHBondContact O-N 2.82Å
64A95.4Very high93.8Very high52 Ų5253.6 Ų53.643%0.4329%0.287SS..Hα-helixtrans-54.3-52.5174.700000111.9D60 I62 S67D60-A64 WeakPolarHBondContact O-CB 3.42Å; D60-A64 PolarHBondContact O-N 2.88Å; I62-A64 VanDerWaalsContact C-N 3.35Å; A64-S67 PolarHBondContact O-N 2.94Å; A64-S67 PolarHBondContact O-OG 3.35Å
65W95.9Very high93.8Very high16 Ų1656 Ų566%0.06129%0.292CS..Hα-helixtrans-68.3-36.7175.8-74.295.9000113.2L14 S17 I62 V63 S67 E68 H69 R409 L410L14-W65 HydrophobicContact CD1-CD2 4.06Å; L14-W65 HydrophobicContact CD1-CE3 3.58Å; L14-W65 HydrophobicContact CD1-CZ3 3.85Å; S17-W65 WeakPolarHBondContact OG-CB 3.27Å; I62-W65 PolarHBondContact O-N 3.17Å; V63-W65 PolarHBondContact O-N 2.98Å; W65-S67 VanDerWaalsContact C-N 3.3Å; W65-S67 PolarHBondContact O-N 3.21Å; W65-E68 PolarHBondContact O-N 3Å; W65-H69 PolarHBondContact O-CD2 3.33Å; W65-H69 PolarHBondContact O-NE2 3.19Å; W65-R409 HydrophobicContact CH2-CB 3.6Å; W65-R409 HydrophobicContact CZ2-CB 4.03Å; W65-L410 HydrophobicContact CH2-CD2 4.45Å; W65-L410 HydrophobicContact CH2-CG 4.4Å; W65-L410 HydrophobicContact CZ2-CD2 4.26Å
66W96.6Very high94Very high0 Ų053.6 Ų53.60%027%0.268CS..Hα-helixtrans-63.7-36.8178.2178.320.3000111.9M20 Q21 Y24 A25 F27 H32 F36 L37 I62 V63 E68 H69M20-W66 HydrophobicContact CB-CD2 3.6Å; M20-W66 HydrophobicContact CB-CE3 3.78Å; M20-W66 HydrophobicContact CB-CG 3.96Å; M20-W66 HydrophobicContact CB-CZ2 4.38Å; M20-W66 HydrophobicContact CB-CZ3 4.22Å; M20-W66 HydrophobicContact CG-CE3 4.28Å; Q21-W66 VanDerWaalsContact OE1-NE1 3.14Å; Y24-W66 HydrophobicContact CD2-CH2 4.37Å; Y24-W66 HydrophobicContact CG-CH2 4.34Å; Y24-W66 HydrophobicContact CG-CZ2 4.48Å; A25-W66 WeakPolarHBondContact O-CZ2 3.4Å; A25-W66 PolarHBondContact O-NE1 3.12Å; F27-W66 HydrophobicContact CB-CD2 3.93Å; F27-W66 HydrophobicContact CB-CE3 4.4Å; F27-W66 HydrophobicContact CB-CG 4.17Å; F27-W66 HydrophobicContact CB-CZ2 4.29Å; F27-W66 HydrophobicContact CD2-CD2 4.12Å; F27-W66 AromaticContact CD2-CE3 3.71Å; F27-W66 HydrophobicContact CD2-CE3 3.71Å; F27-W66 HydrophobicContact CD2-CH2 4.11Å; F27-W66 HydrophobicContact CD2-CZ2 4.45Å; F27-W66 AromaticContact CD2-CZ3 3.73Å; F27-W66 HydrophobicContact CD2-CZ3 3.73Å; F27-W66 HydrophobicContact CE2-CZ3 4.4Å; F27-W66 HydrophobicContact CG-CD2 4.44Å; F27-W66 HydrophobicContact CG-CE3 4.45Å; H32-W66 HydrophobicContact CB-CH2 4.25Å; H32-W66 HydrophobicContact CB-CZ3 4.37Å; H32-W66 AromaticContact CE1-CH2 3.5Å; H32-W66 AromaticContact CE1-CZ2 3.59Å; H32-W66 AromaticContact CG-CH2 3.64Å; H32-W66 AromaticContact ND1-CH2 3.15Å; H32-W66 WeakPolarHBondContact ND1-CH2 3.47Å; H32-W66 AromaticContact ND1-CZ2 3.51Å; H32-W66 AromaticContact ND1-CZ3 3.98Å; F36-W66 HydrophobicContact CD1-CH2 4.45Å; F36-W66 HydrophobicContact CD1-CZ3 4.38Å; F36-W66 AromaticContact CE1-CH2 4Å; F36-W66 HydrophobicContact CE1-CH2 4Å; F36-W66 HydrophobicContact CE1-CZ3 4.35Å; L37-W66 HydrophobicContact CD2-CZ3 4.23Å; I62-W66 WeakPolarHBondContact O-CB 3.17Å; I62-W66 PolarHBondContact O-N 3.45Å; V63-W66 HydrophobicContact CG2-CE3 4.38Å; V63-W66 PolarHBondContact O-N 3.27Å; W66-E68 PolarHBondContact O-N 3.49Å; W66-E68 VanDerWaalsContact O-N 3.1Å; W66-H69 PolarHBondContact O-N 3.31Å; W66-H69 VanDerWaalsContact O-N 3.13Å
67S95.4Very high94.2Very high57 Ų5748.7 Ų48.740%0.39925%0.245SC..G310 helixtrans-59.8-21.9177.378.30000114.2V63 A64 W65V63-S67 WeakPolarHBondContact O-CB 3.31Å; V63-S67 PolarHBondContact O-N 2.82Å; A64-S67 PolarHBondContact O-N 2.94Å; A64-S67 PolarHBondContact O-OG 3.35Å; W65-S67 VanDerWaalsContact C-N 3.3Å; W65-S67 PolarHBondContact O-N 3.21Å
68E93.6Very high94.3Very high98 Ų9849.4 Ų49.446%0.45825%0.249SC..G310 helixtrans-88.2-20.7-179.6-60.3177158.100113.4W65 W66 R70 R409W65-E68 PolarHBondContact O-N 3Å; W66-E68 PolarHBondContact O-N 3.49Å; W66-E68 VanDerWaalsContact O-N 3.1Å; E68-R70 PolarHBondContact O-N 3.26Å; E68-R70 VanDerWaalsContact O-N 3.12Å; E68-R409 IonicContact OE1-CZ 3.89Å; E68-R409 VanDerWaalsContact OE1-CZ 3.31Å; E68-R409 IonicContact OE1-NH1 2.67Å; E68-R409 PolarHBondContact OE1-NH1 3.34Å; E68-R409 IonicContact OE1-NH2 2.77Å; E68-R409 PolarHBondContact OE1-NH2 3.27Å; E68-R409 IonicContact OE2-CZ 3.66Å; E68-R409 IonicContact OE2-NH1 2.9Å; E68-R409 PolarHBondContact OE2-NH1 2.68Å; E68-R409 IonicContact OE2-NH2 2.79Å; E68-R409 PolarHBondContact OE2-NH2 3.04Å
69H94.1Very high94.4Very high12 Ų1252.7 Ų52.76%0.05627%0.267CS..G310 helixtrans-77.814.2175.1-54-42000112.8S17 Y18 Q21 W65 W66 M72S17-H69 PolarHBondContact OG-NE2 3.39Å; Y18-H69 AromaticContact CD1-CE1 3.88Å; Y18-H69 AromaticContact CD1-NE2 3.79Å; Y18-H69 AromaticContact CE1-CE1 3.3Å; Y18-H69 WeakPolarHBondContact CE1-CE1 3.27Å; Y18-H69 AromaticContact CE1-ND1 3.47Å; Y18-H69 WeakPolarHBondContact CE1-ND1 3.41Å; Y18-H69 AromaticContact CE1-NE2 3.71Å; Y18-H69 AromaticContact CE2-CE1 3.91Å; Y18-H69 AromaticContact CZ-CE1 3.32Å; Y18-H69 AromaticContact CZ-ND1 3.87Å; Y18-H69 AromaticContact CZ-NE2 3.89Å; Q21-H69 HydrophobicContact CB-CB 4.01Å; Q21-H69 VanDerWaalsContact CD-O 3.28Å; Q21-H69 HydrophobicContact CG-CB 3.76Å; Q21-H69 PolarHBondContact NE2-O 3Å; W65-H69 PolarHBondContact O-CD2 3.33Å; W65-H69 PolarHBondContact O-NE2 3.19Å; W66-H69 PolarHBondContact O-N 3.31Å; W66-H69 VanDerWaalsContact O-N 3.13Å; H69-M72 HydrophobicContact CB-CB 4.4Å; H69-M72 HydrophobicContact CB-CE 4.26Å; H69-M72 HydrophobicContact CB-SD 4.43Å; H69-M72 WeakPolarHBondContact O-CB 3.01Å; H69-M72 PolarHBondContact O-N 2.8Å
70R91.4Very high94.4Very high183 Ų18354.5 Ų54.569%0.69128%0.276SS*.THydrogen-bonded Turntrans-55.3142.6-178.9-168178.2-176.7-1580.9111.5D26 E68 M72D26-R70 HydrophobicContact CB-CG 4.24Å; E68-R70 PolarHBondContact O-N 3.26Å; E68-R70 VanDerWaalsContact O-N 3.12Å; R70-M72 PolarHBondContact O-N 2.86Å
71C88.4Confident94.5Very high71 Ų7155.1 Ų55.148%0.4827%0.273SS..THydrogen-bonded Turntrans65.1-6.3-169.8-59.90000115.7D26 R210D26-C71 PolarHBondContact OD1-N 2.77Å; D26-C71 PolarHBondContact OD2-N 2.81Å; C71-R210 PolarHBondContact O-NH1 2.68Å; C71-R210 PolarHBondContact O-NH2 3.47Å
72M92.3Very high94.6Very high46 Ų4657.3 Ų57.323%0.22729%0.286CS..  trans-65.5137.4176.5-169175.8-64.200111.2Y18 Q21 H69 R70 D76 A77 E80Y18-M72 HydrophobicContact CD1-SD 4.15Å; Y18-M72 HydrophobicContact CE1-CE 3.99Å; Y18-M72 HydrophobicContact CE1-SD 3.87Å; Q21-M72 HydrophobicContact CG-CB 4.11Å; Q21-M72 PolarHBondContact NE2-O 3.2Å; H69-M72 HydrophobicContact CB-CB 4.4Å; H69-M72 HydrophobicContact CB-CE 4.26Å; H69-M72 HydrophobicContact CB-SD 4.43Å; H69-M72 WeakPolarHBondContact O-CB 3.01Å; H69-M72 PolarHBondContact O-N 2.8Å; R70-M72 PolarHBondContact O-N 2.86Å; M72-D76 HydrophobicContact CG-CB 3.83Å; M72-A77 HydrophobicContact CG-CB 4.4Å; M72-A77 HydrophobicContact SD-CB 3.96Å; M72-E80 HydrophobicContact SD-CG 4.35Å
73M90.8Very high94.6Very high27 Ų2760.9 Ų60.913%0.13330%0.302CS..  trans-69.9154174.2-73.1-175.4157.100111.1E75 D76 A77 V207 R210M73-E75 VanDerWaalsContact C-N 3.25Å; M73-E75 PolarHBondContact O-N 2.94Å; M73-D76 HydrophobicContact CB-CB 4.29Å; M73-D76 PolarHBondContact O-N 3.09Å; M73-D76 VanDerWaalsContact O-N 3.15Å; M73-A77 PolarHBondContact O-N 3Å; M73-V207 HydrophobicContact CE-CB 4.22Å; M73-V207 HydrophobicContact CE-CG2 3.51Å; M73-V207 HydrophobicContact SD-CG2 4.02Å; M73-R210 HydrophobicContact CE-CB 4.36Å
74K94.1Very high94.6Very high86 Ų8660.1 Ų60.137%0.37430%0.297SS..Hα-helixtrans-63-38.4179.5-67.7-173.6171.3-160.70111.1A22 R23 A77 M78A22-K74 WeakPolarHBondContact O-CB 3.2Å; A22-K74 VanDerWaalsContact O-CD 3.23Å; A22-K74 WeakPolarHBondContact O-CD 3.36Å; A22-K74 VanDerWaalsContact O-CG 3.3Å; A22-K74 WeakPolarHBondContact O-CG 3.4Å; R23-K74 PolarHBondContact O-NZ 3.41Å; K74-A77 PolarHBondContact O-N 3.25Å; K74-M78 WeakPolarHBondContact O-CG 3.39Å; K74-M78 PolarHBondContact O-N 3.43Å
75E92.9Very high94.6Very high104 Ų10458 Ų5849%0.48628%0.279SS..Hα-helixtrans-62.3-40.6174.6-62.479.6-18000112M73 M78 L79M73-E75 VanDerWaalsContact C-N 3.25Å; M73-E75 PolarHBondContact O-N 2.94Å; E75-M78 HydrophobicContact CG-CE 4.49Å; E75-L79 WeakPolarHBondContact O-CB 3.47Å; E75-L79 PolarHBondContact O-N 2.77Å
76D93.9Very high94.7Very high32 Ų3259.8 Ų59.817%0.17129%0.288CS..Hα-helixtrans-73.2-38.2176.2-73.7-34.3000111.8M72 M73 M78 L79 E80 R203M72-D76 HydrophobicContact CG-CB 3.83Å; M73-D76 HydrophobicContact CB-CB 4.29Å; M73-D76 PolarHBondContact O-N 3.09Å; M73-D76 VanDerWaalsContact O-N 3.15Å; D76-M78 VanDerWaalsContact C-N 3.34Å; D76-M78 PolarHBondContact O-N 2.79Å; D76-L79 CarbonylContact O-C 3.54Å; D76-L79 WeakPolarHBondContact O-CA 3.35Å; D76-L79 WeakPolarHBondContact O-CB 3.4Å; D76-L79 PolarHBondContact O-N 3.4Å; D76-L79 VanDerWaalsContact O-N 3.08Å; D76-E80 WeakPolarHBondContact O-CG 3.39Å; D76-E80 PolarHBondContact O-N 3.47Å; D76-R203 IonicContact OD1-CZ 3.39Å; D76-R203 VanDerWaalsContact OD1-CZ 3.23Å; D76-R203 IonicContact OD1-NH1 3.73Å; D76-R203 PolarHBondContact OD1-NH1 3.48Å; D76-R203 IonicContact OD1-NH2 2.74Å; D76-R203 PolarHBondContact OD1-NH2 2.9Å; D76-R203 IonicContact OD2-CZ 3.66Å; D76-R203 IonicContact OD2-NH1 3.49Å; D76-R203 IonicContact OD2-NH2 2.91Å; D76-R203 PolarHBondContact OD2-NH2 3.27Å
77A96.8Very high94.6Very high0 Ų060.7 Ų60.70%029%0.293CS..Hα-helixtrans-63.3-39.6173.800000112Y18 Q21 A22 M72 M73 K74 L79 Y81Y18-A77 HydrophobicContact CD1-CB 4.45Å; Q21-A77 HydrophobicContact CB-CB 3.85Å; Q21-A77 HydrophobicContact CG-CB 3.74Å; A22-A77 HydrophobicContact CB-CB 3.99Å; M72-A77 HydrophobicContact CG-CB 4.4Å; M72-A77 HydrophobicContact SD-CB 3.96Å; M73-A77 PolarHBondContact O-N 3Å; K74-A77 PolarHBondContact O-N 3.25Å; A77-L79 VanDerWaalsContact C-N 3.33Å; A77-Y81 WeakPolarHBondContact O-CB 3.46Å; A77-Y81 PolarHBondContact O-N 3.2Å
78M97.2Very high94.7Very high98 Ų9858.7 Ų58.748%0.48328%0.278SS..Hα-helixtrans-63.9-37.5170-70.8-172.9-68.400112.2A22 K74 E75 D76 L82A22-M78 HydrophobicContact CB-CG 3.66Å; K74-M78 WeakPolarHBondContact O-CG 3.39Å; K74-M78 PolarHBondContact O-N 3.43Å; E75-M78 HydrophobicContact CG-CE 4.49Å; D76-M78 VanDerWaalsContact C-N 3.34Å; D76-M78 PolarHBondContact O-N 2.79Å; M78-L82 WeakPolarHBondContact O-CG 3.44Å; M78-L82 PolarHBondContact O-N 2.83Å; M78-L82 VanDerWaalsContact O-N 3.09Å
79L95.4Very high94.8Very high77 Ų7755.1 Ų55.140%0.40326%0.261SS..Hα-helixtrans-70.8-41.5177.9-176.361.3000112.5E75 D76 A77 L82 K83E75-L79 WeakPolarHBondContact O-CB 3.47Å; E75-L79 PolarHBondContact O-N 2.77Å; D76-L79 CarbonylContact O-C 3.54Å; D76-L79 WeakPolarHBondContact O-CA 3.35Å; D76-L79 WeakPolarHBondContact O-CB 3.4Å; D76-L79 PolarHBondContact O-N 3.4Å; D76-L79 VanDerWaalsContact O-N 3.08Å; A77-L79 VanDerWaalsContact C-N 3.33Å; L79-L82 PolarHBondContact O-N 2.84Å; L79-K83 HydrophobicContact CG-CD 4.17Å; L79-K83 HydrophobicContact CG-CG 4.47Å; L79-K83 WeakPolarHBondContact O-CB 3.49Å; L79-K83 VanDerWaalsContact O-CG 3.23Å; L79-K83 WeakPolarHBondContact O-CG 3.34Å; L79-K83 PolarHBondContact O-N 3.42Å
80E95.7Very high95Very high50 Ų5054.9 Ų54.923%0.23426%0.26CS..Hα-helixtrans-66.6-41.2174.6-65.2-44.1136.200111.7Y18 M72 D76 L82 K83 I84Y18-E80 HydrophobicContact CD1-CB 3.84Å; Y18-E80 HydrophobicContact CE1-CB 3.52Å; Y18-E80 HydrophobicContact CE1-CG 4.02Å; Y18-E80 HydrophobicContact CE2-CB 4.32Å; Y18-E80 HydrophobicContact CG-CB 4.37Å; M72-E80 HydrophobicContact SD-CG 4.35Å; D76-E80 WeakPolarHBondContact O-CG 3.39Å; D76-E80 PolarHBondContact O-N 3.47Å; E80-L82 VanDerWaalsContact C-N 3.3Å; E80-L82 PolarHBondContact O-N 2.99Å; E80-K83 PolarHBondContact O-N 2.93Å; E80-K83 VanDerWaalsContact O-N 3.14Å; E80-K83 WeakPolarHBondContact OE1-CD 3.45Å; E80-K83 IonicContact OE1-NZ 2.79Å; E80-K83 PolarHBondContact OE1-NZ 2.86Å; E80-K83 WeakPolarHBondContact OE2-CD 3.23Å; E80-K83 IonicContact OE2-NZ 3.52Å; E80-I84 WeakPolarHBondContact O-CG1 3.2Å; E80-I84 PolarHBondContact O-N 3.45Å
81Y97.3Very high95.3Very high82 Ų8250.1 Ų50.132%0.32224%0.243SC..Hα-helixtrans-51.7-51170.3-176.7-73.3000110.7L15 A19 A77 I84 A85L15-Y81 HydrophobicContact CB-CD2 4.02Å; L15-Y81 HydrophobicContact CB-CE2 3.65Å; L15-Y81 HydrophobicContact CD2-CD1 4.17Å; L15-Y81 HydrophobicContact CD2-CD2 3.77Å; L15-Y81 HydrophobicContact CD2-CE1 4.34Å; L15-Y81 HydrophobicContact CD2-CE2 3.99Å; L15-Y81 HydrophobicContact CD2-CG 3.85Å; L15-Y81 VanDerWaalsContact CD2-O 3.31Å; L15-Y81 WeakPolarHBondContact CD2-O 3.36Å; L15-Y81 HydrophobicContact CG-CD2 4.48Å; L15-Y81 HydrophobicContact CG-CE2 4.29Å; L15-Y81 VanDerWaalsContact O-CD2 3.23Å; L15-Y81 WeakPolarHBondContact O-CD2 3.32Å; L15-Y81 WeakPolarHBondContact O-CE2 3.42Å; A19-Y81 HydrophobicContact CB-CD2 4.37Å; A19-Y81 HydrophobicContact CB-CE2 4.29Å; A77-Y81 WeakPolarHBondContact O-CB 3.46Å; A77-Y81 PolarHBondContact O-N 3.2Å; Y81-I84 PolarHBondContact O-N 2.81Å; Y81-A85 HydrophobicContact CD1-CB 4.33Å; Y81-A85 HydrophobicContact CE1-CB 4.16Å; Y81-A85 WeakPolarHBondContact O-CB 3.31Å; Y81-A85 PolarHBondContact O-N 2.85Å
82L97.4Very high95.7Very high86 Ų8648.7 Ų48.745%0.4524%0.24SC..Hα-helixtrans-70.1-33.2179.4-70.6173.5000112.8M78 L79 E80 I84 Q86M78-L82 WeakPolarHBondContact O-CG 3.44Å; M78-L82 PolarHBondContact O-N 2.83Å; M78-L82 VanDerWaalsContact O-N 3.09Å; L79-L82 PolarHBondContact O-N 2.84Å; E80-L82 VanDerWaalsContact C-N 3.3Å; E80-L82 PolarHBondContact O-N 2.99Å; L82-I84 VanDerWaalsContact C-N 3.3Å; L82-I84 PolarHBondContact O-N 3.19Å; L82-Q86 VanDerWaalsContact O-CB 3.3Å; L82-Q86 WeakPolarHBondContact O-CB 3.43Å; L82-Q86 WeakPolarHBondContact O-CG 3.49Å; L82-Q86 PolarHBondContact O-N 2.98Å
83K95.6Very high96Very high75 Ų7547.3 Ų47.333%0.32624%0.235SC..Hα-helixtrans-64.3-33.1176.6-82.1165.8171.5178.20113L79 E80 Q86L79-K83 HydrophobicContact CG-CD 4.17Å; L79-K83 HydrophobicContact CG-CG 4.47Å; L79-K83 WeakPolarHBondContact O-CB 3.49Å; L79-K83 VanDerWaalsContact O-CG 3.23Å; L79-K83 WeakPolarHBondContact O-CG 3.34Å; L79-K83 PolarHBondContact O-N 3.42Å; E80-K83 PolarHBondContact O-N 2.93Å; E80-K83 VanDerWaalsContact O-N 3.14Å; E80-K83 WeakPolarHBondContact OE1-CD 3.45Å; E80-K83 IonicContact OE1-NZ 2.79Å; E80-K83 PolarHBondContact OE1-NZ 2.86Å; E80-K83 WeakPolarHBondContact OE2-CD 3.23Å; E80-K83 IonicContact OE2-NZ 3.52Å; K83-Q86 VanDerWaalsContact O-CG 3.23Å; K83-Q86 WeakPolarHBondContact O-CG 3.29Å; K83-Q86 PolarHBondContact O-NE2 2.83Å
84I95.9Very high96.3Very high10 Ų1048.9 Ų48.95%0.05124%0.244CC..Hα-helixtrans-83.8-49.7175.1-65.1161.9000110.1T11 L14 L15 Y18 E80 Y81 L82 Q86 D87 L400T11-I84 HydrophobicContact CG2-CG2 3.74Å; L14-I84 HydrophobicContact CD2-CD1 3.8Å; L14-I84 HydrophobicContact CG-CD1 4.19Å; L15-I84 HydrophobicContact CD2-CB 4.01Å; L15-I84 HydrophobicContact CD2-CG2 3.99Å; L15-I84 HydrophobicContact CG-CG2 4.38Å; Y18-I84 HydrophobicContact CD2-CD1 3.97Å; Y18-I84 HydrophobicContact CE2-CD1 3.42Å; Y18-I84 VanDerWaalsContact CE2-CD1 3.42Å; E80-I84 WeakPolarHBondContact O-CG1 3.2Å; E80-I84 PolarHBondContact O-N 3.45Å; Y81-I84 PolarHBondContact O-N 2.81Å; L82-I84 VanDerWaalsContact C-N 3.3Å; L82-I84 PolarHBondContact O-N 3.19Å; I84-Q86 PolarHBondContact O-N 2.86Å; I84-D87 PolarHBondContact O-N 3.28Å; I84-D87 VanDerWaalsContact O-N 3.12Å; I84-L400 HydrophobicContact CG1-CD2 4.43Å
85A96.7Very high96.5Very high7 Ų746.3 Ų46.36%0.05823%0.232CC..Hα-helixtrans-61-30.8-176.100000113.4L15 Y81 D87 L88 Y91L15-A85 HydrophobicContact CD1-CB 4.3Å; L15-A85 HydrophobicContact CD2-CB 4.25Å; Y81-A85 HydrophobicContact CD1-CB 4.33Å; Y81-A85 HydrophobicContact CE1-CB 4.16Å; Y81-A85 WeakPolarHBondContact O-CB 3.31Å; Y81-A85 PolarHBondContact O-N 2.85Å; A85-D87 PolarHBondContact O-N 2.68Å; A85-L88 WeakPolarHBondContact O-CB 3.39Å; A85-L88 WeakPolarHBondContact O-CG 3.46Å; A85-L88 PolarHBondContact O-N 2.82Å; A85-Y91 HydrophobicContact CB-CD2 4.38Å; A85-Y91 HydrophobicContact CB-CE2 4.44Å; A85-Y91 VanDerWaalsContact O-CB 3.25Å; A85-Y91 WeakPolarHBondContact O-CB 3.38Å; A85-Y91 VanDerWaalsContact O-CD2 3.23Å; A85-Y91 WeakPolarHBondContact O-CD2 3.43Å
86Q96.3Very high96.8Very high55 Ų5541.6 Ų41.626%0.25721%0.21SC..THydrogen-bonded Turntrans-63.2-23.4178.265.5177.9-23.600114.6L82 K83 I84 Y91 R396 K443L82-Q86 VanDerWaalsContact O-CB 3.3Å; L82-Q86 WeakPolarHBondContact O-CB 3.43Å; L82-Q86 WeakPolarHBondContact O-CG 3.49Å; L82-Q86 PolarHBondContact O-N 2.98Å; K83-Q86 VanDerWaalsContact O-CG 3.23Å; K83-Q86 WeakPolarHBondContact O-CG 3.29Å; K83-Q86 PolarHBondContact O-NE2 2.83Å; I84-Q86 PolarHBondContact O-N 2.86Å; Q86-Y91 VanDerWaalsContact CA-CD1 3.44Å; Q86-Y91 HydrophobicContact CB-CD1 3.95Å; Q86-Y91 HydrophobicContact CB-CE1 3.69Å; Q86-Y91 HydrophobicContact CB-CG 4.47Å; Q86-R396 VanDerWaalsContact NE2-NH2 3.12Å; Q86-K443 PolarHBondContact O-NZ 2.7Å
87D96Very high97Very high18 Ų1844.6 Ų44.610%0.09622%0.222CC..THydrogen-bonded Turntrans-88.8-10.9-176-63.7-17.2000112.3I84 A85 R396 T398 A399 K443 Y444I84-D87 PolarHBondContact O-N 3.28Å; I84-D87 VanDerWaalsContact O-N 3.12Å; A85-D87 PolarHBondContact O-N 2.68Å; D87-R396 IonicContact OD1-NH2 3.54Å; D87-R396 PolarHBondContact OD1-NH2 3.2Å; D87-T398 HydrophobicContact CB-CG2 4.05Å; D87-T398 WeakPolarHBondContact OD2-CA 3.48Å; D87-T398 WeakPolarHBondContact OD2-CB 3.31Å; D87-A399 PolarHBondContact OD2-N 2.88Å; D87-K443 WeakPolarHBondContact O-CB 3.48Å; D87-K443 VanDerWaalsContact O-CD 3.29Å; D87-K443 WeakPolarHBondContact O-CD 3.34Å; D87-Y444 HydrophobicContact CB-CE2 4.39Å; D87-Y444 WeakPolarHBondContact OD1-CE2 3.37Å; D87-Y444 PolarHBondContact OD1-OH 3.45Å
88L96.8Very high97Very high16 Ų1644.8 Ų44.88%0.08422%0.223CC..SBendtrans-59.8138.5170.2-63173.8000110.6I5 C7 T11 A85 M90 Y91 K443I5-L88 HydrophobicContact CG2-CB 4.4Å; I5-L88 HydrophobicContact CG2-CD1 4.08Å; C7-L88 HydrophobicContact CB-CD1 4Å; T11-L88 HydrophobicContact CG2-CD2 4.25Å; A85-L88 WeakPolarHBondContact O-CB 3.39Å; A85-L88 WeakPolarHBondContact O-CG 3.46Å; A85-L88 PolarHBondContact O-N 2.82Å; L88-M90 VanDerWaalsContact C-N 3.3Å; L88-M90 PolarHBondContact O-N 3.19Å; L88-Y91 WeakPolarHBondContact O-CB 3.29Å; L88-Y91 PolarHBondContact O-N 2.89Å; L88-K443 PolarHBondContact O-NZ 2.83Å
89E96.6Very high97.1Very high23 Ų2345.4 Ų45.411%0.10722%0.22CC..THydrogen-bonded Turntrans-58.2-40.2-168.6-58.696.4126.800112.7L124 H433E89-L124 HydrophobicContact CB-CB 4.15Å; E89-L124 HydrophobicContact CB-CD2 4.3Å; E89-L124 HydrophobicContact CG-CB 4.33Å; E89-H433 IonicContact OE1-CE1 3.97Å; E89-H433 IonicContact OE1-CG 3.62Å; E89-H433 IonicContact OE1-ND1 2.74Å; E89-H433 PolarHBondContact OE1-ND1 2.96Å; E89-H433 IonicContact OE2-ND1 3.67Å
90M97.9Very high97.2Very high6 Ų641.9 Ų41.93%0.0320%0.202CC..THydrogen-bonded Turntrans-82.7-10179.9-56.9-173.964.900114.4E4 I5 Y6 L88 G92 V93 Y95 L124E4-M90 WeakPolarHBondContact O-CE 3.2Å; I5-M90 HydrophobicContact CG2-CB 4.17Å; Y6-M90 PolarHBondContact N-SD 3.09Å; Y6-M90 VanDerWaalsContact N-SD 3.41Å; L88-M90 VanDerWaalsContact C-N 3.3Å; L88-M90 PolarHBondContact O-N 3.19Å; M90-G92 PolarHBondContact O-N 3.38Å; M90-V93 PolarHBondContact O-N 3.22Å; M90-Y95 WeakPolarHBondContact CA-OH 3.44Å; M90-Y95 HydrophobicContact CB-CE2 4.34Å; M90-Y95 HydrophobicContact CE-CD2 4.48Å; M90-Y95 HydrophobicContact CE-CE2 3.78Å; M90-Y95 WeakPolarHBondContact CG-OH 3.49Å; M90-L124 HydrophobicContact CG-CD2 3.57Å; M90-L124 HydrophobicContact SD-CD2 3.81Å
91Y97.8Very high97.2Very high83 Ų8344.7 Ų44.733%0.32521%0.213SC..THydrogen-bonded Turntrans-64.5127.7-175177.1-79.7000112I5 A85 Q86 L88 V93 K443I5-Y91 HydrophobicContact CD1-CD2 4.45Å; A85-Y91 HydrophobicContact CB-CD2 4.38Å; A85-Y91 HydrophobicContact CB-CE2 4.44Å; A85-Y91 VanDerWaalsContact O-CB 3.25Å; A85-Y91 WeakPolarHBondContact O-CB 3.38Å; A85-Y91 VanDerWaalsContact O-CD2 3.23Å; A85-Y91 WeakPolarHBondContact O-CD2 3.43Å; Q86-Y91 VanDerWaalsContact CA-CD1 3.44Å; Q86-Y91 HydrophobicContact CB-CD1 3.95Å; Q86-Y91 HydrophobicContact CB-CE1 3.69Å; Q86-Y91 HydrophobicContact CB-CG 4.47Å; L88-Y91 WeakPolarHBondContact O-CB 3.29Å; L88-Y91 PolarHBondContact O-N 2.89Å; Y91-V93 PolarHBondContact O-N 2.92Å; Y91-K443 PolarHBondContact O-NZ 3.25Å
92G96.7Very high97Very high42 Ų4246.7 Ų46.743%0.43322%0.224SC..THydrogen-bonded Turntrans77.5-0.417800000114.8M90M90-G92 PolarHBondContact O-N 3.38Å
93V98.2Very high97Very high17 Ų1744 Ų4410%0.10322%0.217CC..  trans-89.6117.6-174.7-174.10000110.8M90 Y91 Y95 D111 Y118M90-V93 PolarHBondContact O-N 3.22Å; Y91-V93 PolarHBondContact O-N 2.92Å; V93-Y95 HydrophobicContact CB-CD2 4.31Å; V93-Y95 HydrophobicContact CB-CE2 3.64Å; V93-Y95 HydrophobicContact CG1-CD1 4.17Å; V93-Y95 HydrophobicContact CG1-CD2 4.04Å; V93-Y95 HydrophobicContact CG1-CE1 3.79Å; V93-Y95 HydrophobicContact CG1-CE2 3.63Å; V93-Y95 HydrophobicContact CG1-CG 4.29Å; V93-Y95 VanDerWaalsContact CG1-CZ 3.5Å; V93-Y95 VanDerWaalsContact O-CD2 3.31Å; V93-Y95 WeakPolarHBondContact O-CD2 3.35Å; V93-Y95 WeakPolarHBondContact O-CE2 3.2Å; V93-Y95 PolarHBondContact O-N 2.83Å; V93-D111 HydrophobicContact CG2-CB 4.34Å; V93-Y118 HydrophobicContact CG1-CE2 4.43Å
94N98.2Very high97.1Very high60 Ų6041 Ų4132%0.32121%0.206SC..EExtended strand (participates in β ladder)trans-89104.4172.7-71.7-99.8000109.5F96 G109 V110 L173N94-F96 HydrophobicContact CB-CE2 3.97Å; N94-F96 VanDerWaalsContact O-CD2 3.29Å; N94-F96 WeakPolarHBondContact O-CD2 3.14Å; N94-G109 WeakPolarHBondContact O-CA 3.12Å; N94-V110 HydrophobicContact CB-CB 4.34Å; N94-V110 WeakPolarHBondContact CB-O 3.37Å; N94-V110 PolarHBondContact N-O 3.11Å; N94-V110 PolarHBondContact ND2-O 3.45Å; N94-V110 PolarHBondContact O-N 2.79Å; N94-L173 HydrophobicContact CB-CD1 3.74Å
95Y98Very high97.1Very high32 Ų3244.4 Ų44.413%0.12522%0.221CC..EExtended strand (participates in β ladder)trans-81.8139.8-178.1-64.4-89.4000113.1M90 V93 W107 L108 Y118 R123M90-Y95 WeakPolarHBondContact CA-OH 3.44Å; M90-Y95 HydrophobicContact CB-CE2 4.34Å; M90-Y95 HydrophobicContact CE-CD2 4.48Å; M90-Y95 HydrophobicContact CE-CE2 3.78Å; M90-Y95 WeakPolarHBondContact CG-OH 3.49Å; V93-Y95 HydrophobicContact CB-CD2 4.31Å; V93-Y95 HydrophobicContact CB-CE2 3.64Å; V93-Y95 HydrophobicContact CG1-CD1 4.17Å; V93-Y95 HydrophobicContact CG1-CD2 4.04Å; V93-Y95 HydrophobicContact CG1-CE1 3.79Å; V93-Y95 HydrophobicContact CG1-CE2 3.63Å; V93-Y95 HydrophobicContact CG1-CG 4.29Å; V93-Y95 VanDerWaalsContact CG1-CZ 3.5Å; V93-Y95 VanDerWaalsContact O-CD2 3.31Å; V93-Y95 WeakPolarHBondContact O-CD2 3.35Å; V93-Y95 WeakPolarHBondContact O-CE2 3.2Å; V93-Y95 PolarHBondContact O-N 2.83Å; Y95-W107 HydrophobicContact CD1-CB 4.32Å; Y95-L108 CarbonylContact C-O 3.58Å; Y95-L108 WeakPolarHBondContact CA-O 3.46Å; Y95-Y118 HydrophobicContact CE1-CD1 4.38Å; Y95-Y118 HydrophobicContact CE1-CD2 4.28Å; Y95-Y118 HydrophobicContact CE1-CE1 4.03Å; Y95-Y118 AromaticContact CE1-CE2 3.97Å; Y95-Y118 HydrophobicContact CE1-CE2 3.97Å; Y95-Y118 AromaticContact CE1-CZ 3.86Å; Y95-R123 HydrophobicContact CD1-CB 4.27Å; Y95-R123 HydrophobicContact CD1-CG 4.08Å; Y95-R123 HydrophobicContact CE1-CB 3.65Å; Y95-R123 HydrophobicContact CE1-CG 3.97Å; Y95-R123 PolarHBondContact OH-O 3.25Å
96F98.1Very high97.2Very high5 Ų544.1 Ų44.12%0.02222%0.219CC..EExtended strand (participates in β ladder)trans-140.4134.9179-68.8-82000111.6N94 I98 W107 L108 V110 I166 R169 I170 L173N94-F96 HydrophobicContact CB-CE2 3.97Å; N94-F96 VanDerWaalsContact O-CD2 3.29Å; N94-F96 WeakPolarHBondContact O-CD2 3.14Å; F96-I98 PolarHBondContact O-N 2.9Å; F96-W107 CarbonylContact O-C 3.49Å; F96-W107 WeakPolarHBondContact O-CA 3.42Å; F96-L108 HydrophobicContact CB-CB 4.32Å; F96-L108 PolarHBondContact N-O 2.6Å; F96-L108 PolarHBondContact O-N 2.83Å; F96-V110 HydrophobicContact CD2-CG2 4.1Å; F96-V110 HydrophobicContact CE2-CG2 4.04Å; F96-I166 HydrophobicContact CD1-CG2 3.55Å; F96-I166 HydrophobicContact CE1-CG2 4.02Å; F96-I166 HydrophobicContact CG-CG2 4.48Å; F96-R169 HydrophobicContact CE1-CB 4.19Å; F96-R169 HydrophobicContact CE1-CG 4.37Å; F96-R169 HydrophobicContact CZ-CB 4.26Å; F96-R169 HydrophobicContact CZ-CG 4.12Å; F96-R169 VanDerWaalsContact CZ-NE 3.33Å; F96-I170 HydrophobicContact CB-CD1 4.09Å; F96-I170 HydrophobicContact CB-CG1 4.35Å; F96-I170 HydrophobicContact CD1-CD1 4.02Å; F96-I170 HydrophobicContact CD1-CG1 3.64Å; F96-I170 HydrophobicContact CD2-CD1 4.38Å; F96-I170 HydrophobicContact CD2-CG1 3.74Å; F96-I170 HydrophobicContact CE1-CD1 4.44Å; F96-I170 HydrophobicContact CE1-CG1 3.6Å; F96-I170 HydrophobicContact CE2-CG1 3.75Å; F96-I170 HydrophobicContact CG-CD1 3.93Å; F96-I170 HydrophobicContact CG-CG1 3.66Å; F96-I170 HydrophobicContact CZ-CG1 3.65Å; F96-L173 HydrophobicContact CE2-CD1 3.84Å; F96-L173 HydrophobicContact CZ-CD1 3.74Å
97E98Very high97.3Very high94 Ų9443.4 Ų43.444%0.43921%0.214SC..EExtended strand (participates in β ladder)trans-74123.8172.2-59.5-174.1133.600110.5W107 K120 P162E97-W107 HydrophobicContact CB-CZ3 4.47Å; E97-W107 HydrophobicContact CG-CE3 4Å; E97-W107 HydrophobicContact CG-CH2 3.65Å; E97-W107 HydrophobicContact CG-CZ2 4.48Å; E97-W107 HydrophobicContact CG-CZ3 3.37Å; E97-K120 IonicContact OE1-NZ 2.68Å; E97-K120 PolarHBondContact OE1-NZ 2.89Å; E97-P162 VanDerWaalsContact O-CD 3.27Å; E97-P162 WeakPolarHBondContact O-CD 3.33Å
98I98.2Very high97.4Very high4 Ų442.6 Ų42.62%0.02121%0.209CC..EExtended strand (participates in β ladder)trans-135.8166.5178.861.6152.8000111F96 L106 L108 I117 F159 Y160 F462F96-I98 PolarHBondContact O-N 2.9Å; I98-L106 HydrophobicContact CD1-CB 4.41Å; I98-L106 HydrophobicContact CG1-CB 4.08Å; I98-L106 WeakPolarHBondContact CG1-O 3.28Å; I98-L106 PolarHBondContact N-O 3.1Å; I98-L106 PolarHBondContact O-N 3.23Å; I98-L106 VanDerWaalsContact O-O 3.13Å; I98-L108 HydrophobicContact CD1-CB 3.92Å; I98-L108 HydrophobicContact CG1-CB 4.07Å; I98-L108 HydrophobicContact CG2-CB 3.98Å; I98-I117 HydrophobicContact CD1-CD1 4.28Å; I98-F159 HydrophobicContact CB-CB 4.42Å; I98-F159 HydrophobicContact CB-CD2 3.83Å; I98-F159 HydrophobicContact CB-CE2 4.5Å; I98-F159 HydrophobicContact CB-CG 4.37Å; I98-F159 HydrophobicContact CD1-CB 3.91Å; I98-F159 HydrophobicContact CD1-CD1 4.48Å; I98-F159 HydrophobicContact CD1-CD2 4.2Å; I98-F159 HydrophobicContact CD1-CG 3.97Å; I98-F159 HydrophobicContact CG2-CD2 3.43Å; I98-F159 VanDerWaalsContact CG2-CD2 3.43Å; I98-F159 HydrophobicContact CG2-CE2 3.62Å; I98-F159 HydrophobicContact CG2-CG 4.31Å; I98-Y160 CarbonylContact C-O 3.59Å; I98-Y160 WeakPolarHBondContact CA-O 3.06Å; I98-F462 HydrophobicContact CD1-CE2 3.95Å; I98-F462 HydrophobicContact CD1-CZ 4.21Å
99R98.2Very high97.5Very high112 Ų11241.8 Ų41.842%0.42321%0.205SC..EExtended strand (participates in β ladder)trans-127.5147167.4-61179.3-172.5-93.3-4.5111.7G103 S104 E105 F159 Y160R99-G103 VanDerWaalsContact CD-O 3.29Å; R99-G103 WeakPolarHBondContact CD-O 3.43Å; R99-G103 PolarHBondContact NH1-O 2.7Å; R99-S104 WeakPolarHBondContact CA-O 3.44Å; R99-S104 WeakPolarHBondContact CB-O 3.46Å; R99-S104 WeakPolarHBondContact CG-O 3.47Å; R99-E105 IonicContact CZ-OE1 2.76Å; R99-E105 VanDerWaalsContact CZ-OE1 3.27Å; R99-E105 IonicContact NH1-OE1 3.79Å; R99-E105 PolarHBondContact NH1-OE1 3.16Å; R99-E105 VanDerWaalsContact NH1-OE1 3.11Å; R99-E105 IonicContact NH2-OE1 3.2Å; R99-E105 PolarHBondContact NH2-OE1 3.34Å; R99-F159 CarbonylContact O-C 3.6Å; R99-F159 WeakPolarHBondContact O-CA 3.11Å; R99-F159 WeakPolarHBondContact O-CB 3.47Å; R99-Y160 PolarHBondContact N-O 3.5Å; R99-Y160 PolarHBondContact O-N 3.13Å
100N97Very high97.6Very high2 Ų240.7 Ų40.71%0.01120%0.2CC..  trans-78.2-174.9167.669.98.9000110.9K102 G103 S104 L106 F462 M465N100-K102 PolarHBondContact O-N 3.05Å; N100-K102 WeakPolarHBondContact OD1-CA 3.23Å; N100-K102 WeakPolarHBondContact OD1-CB 3.22Å; N100-K102 PolarHBondContact OD1-N 3.38Å; N100-G103 PolarHBondContact O-N 3Å; N100-G103 PolarHBondContact OD1-N 2.91Å; N100-G103 VanDerWaalsContact OD1-N 3.1Å; N100-S104 WeakPolarHBondContact OD1-CB 3.45Å; N100-S104 PolarHBondContact OD1-N 2.79Å; N100-L106 HydrophobicContact CB-CD1 4.31Å; N100-F462 HydrophobicContact CB-CD1 4.04Å; N100-F462 HydrophobicContact CB-CE1 3.38Å; N100-F462 HydrophobicContact CB-CE2 4.17Å; N100-F462 HydrophobicContact CB-CZ 3.45Å; N100-F462 VanDerWaalsContact CB-CZ 3.45Å; N100-F462 PolarHBondContact ND2-O 3Å; N100-F462 VanDerWaalsContact ND2-O 3.09Å; N100-M465 PolarHBondContact ND2-O 3.01Å
101K95.4Very high97.6Very high109 Ų10940.8 Ų40.847%0.47420%0.2SC..THydrogen-bonded Turntrans-67.2-18.4178.7-66.7-176.5-176.585.30114.2Y160 E463K101-Y160 HydrophobicContact CG-CE2 4.13Å; K101-E463 VanDerWaalsContact CB-OE2 3.31Å; K101-E463 WeakPolarHBondContact CB-OE2 3.49Å; K101-E463 WeakPolarHBondContact CD-OE1 3.41Å; K101-E463 WeakPolarHBondContact CG-OE1 3.48Å; K101-E463 WeakPolarHBondContact CG-OE2 3.38Å; K101-E463 PolarHBondContact N-OE2 3.45Å; K101-E463 IonicContact NZ-OE1 3.27Å; K101-E463 PolarHBondContact NZ-OE1 3.41Å
102K95.1Very high97.5Very high125 Ų12538.7 Ų38.754%0.54320%0.2SC..THydrogen-bonded Turntrans-85.3-12175.7-64.5179179.1159.70113.3N100 E463 N464N100-K102 PolarHBondContact O-N 3.05Å; N100-K102 WeakPolarHBondContact OD1-CA 3.23Å; N100-K102 WeakPolarHBondContact OD1-CB 3.22Å; N100-K102 PolarHBondContact OD1-N 3.38Å; K102-E463 VanDerWaalsContact CD-O 3.32Å; K102-E463 WeakPolarHBondContact CD-O 3.45Å; K102-E463 WeakPolarHBondContact CE-O 3.47Å; K102-E463 PolarHBondContact NZ-O 3.03Å; K102-N464 PolarHBondContact NZ-OD1 3.03Å
103G95.5Very high97.4Very high30 Ų3038.2 Ų38.231%0.30919%0.188SC..  trans92.80.7-179.100000115.1R99 N100R99-G103 VanDerWaalsContact CD-O 3.29Å; R99-G103 WeakPolarHBondContact CD-O 3.43Å; R99-G103 PolarHBondContact NH1-O 2.7Å; N100-G103 PolarHBondContact O-N 3Å; N100-G103 PolarHBondContact OD1-N 2.91Å; N100-G103 VanDerWaalsContact OD1-N 3.1Å
104S97.6Very high97.3Very high12 Ų1237.4 Ų37.48%0.08418%0.183CC..  trans-51.9138.9175.9-64.40000112.8R99 N100 M465 V466R99-S104 WeakPolarHBondContact CA-O 3.44Å; R99-S104 WeakPolarHBondContact CB-O 3.46Å; R99-S104 WeakPolarHBondContact CG-O 3.47Å; N100-S104 WeakPolarHBondContact OD1-CB 3.45Å; N100-S104 PolarHBondContact OD1-N 2.79Å; S104-M465 PolarHBondContact OG-O 3.18Å; S104-M465 VanDerWaalsContact OG-O 3.09Å; S104-V466 WeakPolarHBondContact CA-OXT 3.21Å; S104-V466 WeakPolarHBondContact CB-OXT 3.43Å; S104-V466 VanDerWaalsContact OG-C 3.28Å; S104-V466 VanDerWaalsContact OG-CA 3.29Å; S104-V466 WeakPolarHBondContact OG-CA 3.49Å; S104-V466 PolarHBondContact OG-OXT 3.14Å
105E97.8Very high97.3Very high81 Ų8134.5 Ų34.538%0.37917%0.167SC..EExtended strand (participates in β ladder)trans-87.4117.8-179.8-66.3-164.5-16600111.5R99 K120R99-E105 IonicContact CZ-OE1 2.76Å; R99-E105 VanDerWaalsContact CZ-OE1 3.27Å; R99-E105 IonicContact NH1-OE1 3.79Å; R99-E105 PolarHBondContact NH1-OE1 3.16Å; R99-E105 VanDerWaalsContact NH1-OE1 3.11Å; R99-E105 IonicContact NH2-OE1 3.2Å; R99-E105 PolarHBondContact NH2-OE1 3.34Å; E105-K120 HydrophobicContact CB-CB 4.27Å; E105-K120 HydrophobicContact CB-CD 4.08Å; E105-K120 HydrophobicContact CB-CG 4.19Å; E105-K120 WeakPolarHBondContact O-CB 3.4Å; E105-K120 WeakPolarHBondContact OE2-CE 3.37Å; E105-K120 IonicContact OE2-NZ 2.76Å
106L98.3Very high97.4Very high1 Ų133.1 Ų33.11%0.00516%0.162CC..EExtended strand (participates in β ladder)trans-133.9158.2-174.3-61.2172.4000110.5I98 N100 I117 Y118 F462 M465I98-L106 HydrophobicContact CD1-CB 4.41Å; I98-L106 HydrophobicContact CG1-CB 4.08Å; I98-L106 WeakPolarHBondContact CG1-O 3.28Å; I98-L106 PolarHBondContact N-O 3.1Å; I98-L106 PolarHBondContact O-N 3.23Å; I98-L106 VanDerWaalsContact O-O 3.13Å; N100-L106 HydrophobicContact CB-CD1 4.31Å; L106-I117 HydrophobicContact CB-CG2 4.27Å; L106-I117 HydrophobicContact CD1-CG2 4.15Å; L106-Y118 WeakPolarHBondContact CA-O 3.49Å; L106-F462 HydrophobicContact CD1-CD2 3.99Å; L106-F462 HydrophobicContact CD1-CE2 3.55Å; L106-F462 HydrophobicContact CD1-CZ 4.28Å; L106-M465 HydrophobicContact CD1-CB 4.15Å; L106-M465 HydrophobicContact CD1-SD 4.08Å; L106-M465 HydrophobicContact CD2-CB 4.12Å; L106-M465 HydrophobicContact CD2-CE 3.68Å; L106-M465 HydrophobicContact CD2-SD 4.01Å
107W98.4Very high97.4Very high40 Ų4032.9 Ų32.915%0.15216%0.161CC..EExtended strand (participates in β ladder)trans-99.9132.7166.4-61.9102.1000110.1Y95 F96 E97 I117 Y118 K120 R123Y95-W107 HydrophobicContact CD1-CB 4.32Å; F96-W107 CarbonylContact O-C 3.49Å; F96-W107 WeakPolarHBondContact O-CA 3.42Å; E97-W107 HydrophobicContact CB-CZ3 4.47Å; E97-W107 HydrophobicContact CG-CE3 4Å; E97-W107 HydrophobicContact CG-CH2 3.65Å; E97-W107 HydrophobicContact CG-CZ2 4.48Å; E97-W107 HydrophobicContact CG-CZ3 3.37Å; W107-I117 WeakPolarHBondContact O-CA 3.16Å; W107-Y118 HydrophobicContact CB-CD2 4.25Å; W107-Y118 PolarHBondContact N-O 3.31Å; W107-Y118 PolarHBondContact O-N 3.15Å; W107-K120 HydrophobicContact CZ2-CD 4.31Å; W107-K120 PolarHBondContact NE1-O 3.44Å; W107-R123 HydrophobicContact CD2-CG 4.34Å; W107-R123 HydrophobicContact CG-CG 4.1Å
108L98.6Very high97.4Very high0 Ų028.5 Ų28.50%014%0.14CC..EExtended strand (participates in β ladder)trans-93.8124.1159.4177.571.3000108.3Y95 F96 I98 V110 L115 I117 F159 I170Y95-L108 CarbonylContact C-O 3.58Å; Y95-L108 WeakPolarHBondContact CA-O 3.46Å; F96-L108 HydrophobicContact CB-CB 4.32Å; F96-L108 PolarHBondContact N-O 2.6Å; F96-L108 PolarHBondContact O-N 2.83Å; I98-L108 HydrophobicContact CD1-CB 3.92Å; I98-L108 HydrophobicContact CG1-CB 4.07Å; I98-L108 HydrophobicContact CG2-CB 3.98Å; L108-V110 HydrophobicContact CD2-CG2 4.04Å; L108-V110 HydrophobicContact CG-CG2 4.14Å; L108-L115 HydrophobicContact CD1-CB 4.37Å; L108-L115 HydrophobicContact CD1-CD2 4.29Å; L108-I117 HydrophobicContact CD1-CD1 3.63Å; L108-F159 HydrophobicContact CD2-CE1 3.98Å; L108-F159 HydrophobicContact CD2-CE2 4.04Å; L108-F159 HydrophobicContact CD2-CZ 3.47Å; L108-F159 VanDerWaalsContact CD2-CZ 3.47Å; L108-I170 HydrophobicContact CD2-CD1 4.23Å; L108-I170 HydrophobicContact CD2-CG2 3.96Å
109G98.6Very high97.4Very high0 Ų032.4 Ų32.40%016%0.159CC..EExtended strand (participates in β ladder)trans-97.9128.6163.800000110.5N94 N116N94-G109 WeakPolarHBondContact O-CA 3.12Å; G109-N116 PolarHBondContact N-O 3.26Å; G109-N116 PolarHBondContact O-N 3.24Å
110V98.5Very high97.2Very high0 Ų030.5 Ų30.50%015%0.153CC..EExtended strand (participates in β ladder)trans-109.9120.8171.4-173.10000108.5N94 F96 L108 L115 W132 I170 L173N94-V110 HydrophobicContact CB-CB 4.34Å; N94-V110 WeakPolarHBondContact CB-O 3.37Å; N94-V110 PolarHBondContact N-O 3.11Å; N94-V110 PolarHBondContact ND2-O 3.45Å; N94-V110 PolarHBondContact O-N 2.79Å; F96-V110 HydrophobicContact CD2-CG2 4.1Å; F96-V110 HydrophobicContact CE2-CG2 4.04Å; L108-V110 HydrophobicContact CD2-CG2 4.04Å; L108-V110 HydrophobicContact CG-CG2 4.14Å; V110-L115 HydrophobicContact CB-CD2 4.25Å; V110-L115 HydrophobicContact CG1-CD2 4.07Å; V110-L115 HydrophobicContact CG2-CD2 3.82Å; V110-W132 HydrophobicContact CG1-CH2 4.12Å; V110-W132 HydrophobicContact CG1-CZ2 3.93Å; V110-I170 HydrophobicContact CG2-CG2 4.4Å; V110-L173 HydrophobicContact CG1-CB 4.05Å
111D97.6Very high97.1Very high7 Ų733.3 Ų33.34%0.03718%0.177CC..  trans-138.7-178.7-177.971.832.5000112.8V93 L113 G114 N116 W132 N177V93-D111 HydrophobicContact CG2-CB 4.34Å; D111-L113 PolarHBondContact O-N 3.13Å; D111-L113 VanDerWaalsContact OD1-CA 3.27Å; D111-L113 WeakPolarHBondContact OD1-CA 3.44Å; D111-L113 WeakPolarHBondContact OD1-CB 3.35Å; D111-L113 PolarHBondContact OD1-N 2.93Å; D111-G114 PolarHBondContact N-O 3.34Å; D111-G114 PolarHBondContact OD1-N 3.39Å; D111-N116 PolarHBondContact OD2-ND2 3.11Å; D111-W132 PolarHBondContact O-NE1 3.1Å; D111-N177 WeakPolarHBondContact O-CB 3.49Å
112A96.1Very high97.2Very high39 Ų3928.4 Ų28.432%0.32216%0.156SC..SBendtrans-73.7-4.3-178.700000114.9N177A112-N177 WeakPolarHBondContact CA-OD1 3.23Å; A112-N177 PolarHBondContact N-OD1 3Å
113L95Very high97.3Very high32 Ų3225.5 Ų25.517%0.16814%0.141CC..SBendtrans-113.7-19.6-176.9-54.1178.1000112.8D111 E393 Y444 L447 R451D111-L113 PolarHBondContact O-N 3.13Å; D111-L113 VanDerWaalsContact OD1-CA 3.27Å; D111-L113 WeakPolarHBondContact OD1-CA 3.44Å; D111-L113 WeakPolarHBondContact OD1-CB 3.35Å; D111-L113 PolarHBondContact OD1-N 2.93Å; L113-E393 HydrophobicContact CD2-CB 4.05Å; L113-Y444 HydrophobicContact CD1-CE1 4.28Å; L113-L447 HydrophobicContact CD1-CD1 3.76Å; L113-R451 PolarHBondContact O-NH1 3.38Å; L113-R451 PolarHBondContact O-NH2 2.92Å
114G96.2Very high97.4Very high0 Ų024.2 Ų24.20%013%0.128CC..EExtended strand (participates in β ladder)trans161.2-148.4175.500000114.6D111 F130 W132D111-G114 PolarHBondContact N-O 3.34Å; D111-G114 PolarHBondContact OD1-N 3.39Å; G114-F130 VanDerWaalsContact CA-O 3.32Å; G114-F130 WeakPolarHBondContact CA-O 3.46Å; G114-W132 WeakPolarHBondContact O-CZ2 3.45Å
115L98.2Very high97.4Very high0 Ų024 Ų240%013%0.125CC..EExtended strand (participates in β ladder)trans-117.5129.2173.9-63.7175.5000109.3L108 V110 G129 F130 W132 I147L108-L115 HydrophobicContact CD1-CB 4.37Å; L108-L115 HydrophobicContact CD1-CD2 4.29Å; V110-L115 HydrophobicContact CB-CD2 4.25Å; V110-L115 HydrophobicContact CG1-CD2 4.07Å; V110-L115 HydrophobicContact CG2-CD2 3.82Å; L115-G129 CarbonylContact O-C 3.59Å; L115-G129 WeakPolarHBondContact O-CA 3.36Å; L115-F130 HydrophobicContact CB-CB 4.5Å; L115-F130 PolarHBondContact N-O 2.9Å; L115-F130 PolarHBondContact O-N 2.95Å; L115-W132 HydrophobicContact CD1-CH2 4.26Å; L115-W132 HydrophobicContact CD1-CZ3 4.09Å; L115-W132 HydrophobicContact CD2-CH2 3.45Å; L115-W132 VanDerWaalsContact CD2-CH2 3.45Å; L115-W132 HydrophobicContact CD2-CZ2 4.05Å; L115-W132 HydrophobicContact CD2-CZ3 4.13Å; L115-W132 HydrophobicContact CG-CH2 3.67Å; L115-W132 HydrophobicContact CG-CZ2 4.32Å; L115-W132 HydrophobicContact CG-CZ3 3.87Å; L115-I147 HydrophobicContact CD1-CD1 3.38Å
116N98.4Very high97.4Very high2 Ų220.7 Ų20.71%0.01111%0.111CC..EExtended strand (participates in β ladder)trans-123.6142-179.4-47.5-43.8000110G109 D111 Y118 P126 I128 L447G109-N116 PolarHBondContact N-O 3.26Å; G109-N116 PolarHBondContact O-N 3.24Å; D111-N116 PolarHBondContact OD2-ND2 3.11Å; N116-Y118 HydrophobicContact CB-CE2 3.71Å; N116-P126 HydrophobicContact CB-CB 3.8Å; N116-P126 HydrophobicContact CB-CG 4.39Å; N116-I128 CarbonylContact C-O 3.49Å; N116-I128 WeakPolarHBondContact CA-O 3.48Å; N116-L447 WeakPolarHBondContact OD1-CD2 3.29Å
117I98.5Very high97.3Very high0 Ų023.7 Ų23.70%012%0.124CC..EExtended strand (participates in β ladder)trans-109.9136.5176.2-47.3-61.1000109.8I98 L106 W107 L108 P126 K127 I128 F157 F462 M465I98-I117 HydrophobicContact CD1-CD1 4.28Å; L106-I117 HydrophobicContact CB-CG2 4.27Å; L106-I117 HydrophobicContact CD1-CG2 4.15Å; W107-I117 WeakPolarHBondContact O-CA 3.16Å; L108-I117 HydrophobicContact CD1-CD1 3.63Å; I117-P126 CarbonylContact O-C 3.6Å; I117-P126 WeakPolarHBondContact O-CA 3.45Å; I117-K127 PolarHBondContact O-N 2.94Å; I117-I128 HydrophobicContact CB-CB 4.2Å; I117-I128 HydrophobicContact CG1-CB 4.28Å; I117-I128 PolarHBondContact N-O 3.38Å; I117-F157 HydrophobicContact CD1-CZ 3.77Å; I117-F157 HydrophobicContact CG1-CZ 4.5Å; I117-F462 HydrophobicContact CD1-CD2 4.32Å; I117-F462 HydrophobicContact CD1-CE2 4.27Å; I117-F462 HydrophobicContact CG1-CD2 4.05Å; I117-F462 HydrophobicContact CG1-CE2 4.47Å; I117-F462 HydrophobicContact CG2-CD2 3.98Å; I117-F462 HydrophobicContact CG2-CE2 4.16Å; I117-M465 HydrophobicContact CG2-CE 4.45Å; I117-M465 HydrophobicContact CG2-SD 3.85Å
118Y98.4Very high97.3Very high3 Ų322 Ų221%0.01212%0.118CC..EExtended strand (participates in β ladder)trans-130.1153178.2-38.8-123.9000110.6V93 Y95 L106 W107 N116 D122 R123 P126V93-Y118 HydrophobicContact CG1-CE2 4.43Å; Y95-Y118 HydrophobicContact CE1-CD1 4.38Å; Y95-Y118 HydrophobicContact CE1-CD2 4.28Å; Y95-Y118 HydrophobicContact CE1-CE1 4.03Å; Y95-Y118 AromaticContact CE1-CE2 3.97Å; Y95-Y118 HydrophobicContact CE1-CE2 3.97Å; Y95-Y118 AromaticContact CE1-CZ 3.86Å; L106-Y118 WeakPolarHBondContact CA-O 3.49Å; W107-Y118 HydrophobicContact CB-CD2 4.25Å; W107-Y118 PolarHBondContact N-O 3.31Å; W107-Y118 PolarHBondContact O-N 3.15Å; N116-Y118 HydrophobicContact CB-CE2 3.71Å; Y118-D122 WeakPolarHBondContact CB-O 3.38Å; Y118-R123 WeakPolarHBondContact CE1-O 3.45Å; Y118-P126 VanDerWaalsContact CD1-CA 3.5Å; Y118-P126 HydrophobicContact CD1-CB 3.81Å; Y118-P126 HydrophobicContact CD1-CG 4.42Å; Y118-P126 HydrophobicContact CD2-CB 4.34Å; Y118-P126 HydrophobicContact CE1-CB 3.62Å; Y118-P126 VanDerWaalsContact CE1-CD 3.48Å; Y118-P126 HydrophobicContact CE1-CG 3.86Å; Y118-P126 HydrophobicContact CE2-CB 4.12Å; Y118-P126 HydrophobicContact CG-CB 4.15Å
119E97.1Very high97.2Very high86 Ų8622 Ų2240%0.40212%0.118SC..EExtended strand (participates in β ladder)trans-72153.1172.5-71.1155.9-168.900110.6A121 D122 K127 M465E119-A121 PolarHBondContact O-N 3.19Å; E119-D122 PolarHBondContact O-N 3.48Å; E119-D122 VanDerWaalsContact O-N 3.12Å; E119-D122 VanDerWaalsContact O-O 3.05Å; E119-K127 HydrophobicContact CG-CG 4.13Å; E119-K127 WeakPolarHBondContact OE1-CE 3.33Å; E119-K127 WeakPolarHBondContact OE2-CE 3.42Å; E119-K127 IonicContact OE2-NZ 2.71Å; E119-K127 PolarHBondContact OE2-NZ 2.98Å; E119-M465 HydrophobicContact CG-CE 3.6Å
120K95.7Very high97.1Very high72 Ų7222.1 Ų22.131%0.31312%0.119SC..THydrogen-bonded Turntrans-52-34.8-174.7-16957.7170.7-178.60114.2E97 E105 W107E97-K120 IonicContact OE1-NZ 2.68Å; E97-K120 PolarHBondContact OE1-NZ 2.89Å; E105-K120 HydrophobicContact CB-CB 4.27Å; E105-K120 HydrophobicContact CB-CD 4.08Å; E105-K120 HydrophobicContact CB-CG 4.19Å; E105-K120 WeakPolarHBondContact O-CB 3.4Å; E105-K120 WeakPolarHBondContact OE2-CE 3.37Å; E105-K120 IonicContact OE2-NZ 2.76Å; W107-K120 HydrophobicContact CZ2-CD 4.31Å; W107-K120 PolarHBondContact NE1-O 3.44Å
121A95.2Very high96.9Very high61 Ų6122.3 Ų22.350%0.50412%0.12SC..THydrogen-bonded Turntrans-88.7-13.3-174.400000115.2E119 Q428E119-A121 PolarHBondContact O-N 3.19Å; A121-Q428 PolarHBondContact O-NE2 3.46Å
122D96.6Very high96.8Very high6 Ų622 Ų223%0.03212%0.118CC..  trans-130.2117.2-175.51759000109.7Y118 E119 L124 T125 K127 L432Y118-D122 WeakPolarHBondContact CB-O 3.38Å; E119-D122 PolarHBondContact O-N 3.48Å; E119-D122 VanDerWaalsContact O-N 3.12Å; E119-D122 VanDerWaalsContact O-O 3.05Å; D122-L124 PolarHBondContact OD1-N 3.18Å; D122-T125 PolarHBondContact OD1-N 2.57Å; D122-T125 PolarHBondContact OD1-OG1 3.44Å; D122-T125 WeakPolarHBondContact OD2-CB 3.47Å; D122-T125 PolarHBondContact OD2-OG1 3.38Å; D122-K127 IonicContact OD2-NZ 3.34Å; D122-K127 PolarHBondContact OD2-NZ 3.29Å; D122-L432 HydrophobicContact CB-CD1 4.04Å; D122-L432 HydrophobicContact CB-CD2 4.21Å
123R97Very high96.5Very high63 Ų6321 Ų2124%0.23811%0.109CC..SBendtrans-107.9-0.8174.3-67.2-171.2-60.3160.37.6113.6Y95 W107 Y118 Y429Y95-R123 HydrophobicContact CD1-CB 4.27Å; Y95-R123 HydrophobicContact CD1-CG 4.08Å; Y95-R123 HydrophobicContact CE1-CB 3.65Å; Y95-R123 HydrophobicContact CE1-CG 3.97Å; Y95-R123 PolarHBondContact OH-O 3.25Å; W107-R123 HydrophobicContact CD2-CG 4.34Å; W107-R123 HydrophobicContact CG-CG 4.1Å; Y118-R123 WeakPolarHBondContact CE1-O 3.45Å; R123-Y429 HydrophobicContact CB-CE1 4.19Å; R123-Y429 PolarHBondContact NE-OH 2.9Å; R123-Y429 PolarHBondContact NH2-OH 2.98Å
124L96.8Very high96.5Very high4 Ų421.2 Ų21.22%0.02111%0.109CC..SBendtrans-87.5-45.7175.7-54.7-173.3000110.7Y6 E89 M90 D122 P126 Y429 L432 H433Y6-L124 HydrophobicContact CD1-CD1 4.16Å; Y6-L124 HydrophobicContact CD1-CD2 4.11Å; Y6-L124 HydrophobicContact CE1-CD1 4.44Å; Y6-L124 HydrophobicContact CG-CD2 4.14Å; E89-L124 HydrophobicContact CB-CB 4.15Å; E89-L124 HydrophobicContact CB-CD2 4.3Å; E89-L124 HydrophobicContact CG-CB 4.33Å; M90-L124 HydrophobicContact CG-CD2 3.57Å; M90-L124 HydrophobicContact SD-CD2 3.81Å; D122-L124 PolarHBondContact OD1-N 3.18Å; L124-P126 WeakPolarHBondContact O-CD 3.32Å; L124-Y429 HydrophobicContact CD1-CD1 4.21Å; L124-Y429 WeakPolarHBondContact CD1-O 3.38Å; L124-Y429 HydrophobicContact CD2-CD1 3.86Å; L124-Y429 HydrophobicContact CD2-CE1 4.41Å; L124-Y429 HydrophobicContact CG-CD1 3.85Å; L124-Y429 HydrophobicContact CG-CE1 4.48Å; L124-L432 HydrophobicContact CD1-CB 3.95Å; L124-H433 HydrophobicContact CD1-CB 3.86Å
125T97.6Very high96.3Very high6 Ų621.4 Ų21.44%0.03711%0.11CC..SBendtrans-104.295.7-171.5-19.10000110.1D122 K127 N436 T446D122-T125 PolarHBondContact OD1-N 2.57Å; D122-T125 PolarHBondContact OD1-OG1 3.44Å; D122-T125 WeakPolarHBondContact OD2-CB 3.47Å; D122-T125 PolarHBondContact OD2-OG1 3.38Å; T125-K127 WeakPolarHBondContact O-CD 3.42Å; T125-K127 PolarHBondContact O-NZ 3.07Å; T125-N436 WeakPolarHBondContact CG2-OD1 3.06Å; T125-N436 PolarHBondContact OG1-ND2 3.14Å; T125-N436 PolarHBondContact OG1-OD1 2.86Å; T125-T446 HydrophobicContact CG2-CG2 3.98Å
126P97.8Very high96Very high12 Ų1223.4 Ų23.48%0.07812%0.117CC..  trans-63.7150.1169.625.1-29.1000109.8N116 I117 Y118 L124 T446 I450N116-P126 HydrophobicContact CB-CB 3.8Å; N116-P126 HydrophobicContact CB-CG 4.39Å; I117-P126 CarbonylContact O-C 3.6Å; I117-P126 WeakPolarHBondContact O-CA 3.45Å; Y118-P126 VanDerWaalsContact CD1-CA 3.5Å; Y118-P126 HydrophobicContact CD1-CB 3.81Å; Y118-P126 HydrophobicContact CD1-CG 4.42Å; Y118-P126 HydrophobicContact CD2-CB 4.34Å; Y118-P126 HydrophobicContact CE1-CB 3.62Å; Y118-P126 VanDerWaalsContact CE1-CD 3.48Å; Y118-P126 HydrophobicContact CE1-CG 3.86Å; Y118-P126 HydrophobicContact CE2-CB 4.12Å; Y118-P126 HydrophobicContact CG-CB 4.15Å; L124-P126 WeakPolarHBondContact O-CD 3.32Å; P126-T446 HydrophobicContact CG-CG2 4.27Å; P126-I450 HydrophobicContact CB-CD1 3.58Å; P126-I450 HydrophobicContact CG-CD1 3.61Å; P126-I450 WeakPolarHBondContact O-CG2 3.34Å
127K97.3Very high95.5Very high64 Ų6423.9 Ų23.928%0.27812%0.12SC..SBendtrans-107.8-24.8-176.7-44.6-55.3-166-1600113I117 E119 D122 T125 I450 M465I117-K127 PolarHBondContact O-N 2.94Å; E119-K127 HydrophobicContact CG-CG 4.13Å; E119-K127 WeakPolarHBondContact OE1-CE 3.33Å; E119-K127 WeakPolarHBondContact OE2-CE 3.42Å; E119-K127 IonicContact OE2-NZ 2.71Å; E119-K127 PolarHBondContact OE2-NZ 2.98Å; D122-K127 IonicContact OD2-NZ 3.34Å; D122-K127 PolarHBondContact OD2-NZ 3.29Å; T125-K127 WeakPolarHBondContact O-CD 3.42Å; T125-K127 PolarHBondContact O-NZ 3.07Å; K127-I450 WeakPolarHBondContact O-CG2 3.5Å; K127-M465 HydrophobicContact CB-CE 4.09Å; K127-M465 HydrophobicContact CG-CE 4.04Å
128I97.6Very high95.3Very high5 Ų524 Ų243%0.02612%0.121CC..EExtended strand (participates in β ladder)trans-139.8136.5-179.9-51.9176.1000108.4N116 I117 F130 R458 Q461 F462 M465N116-I128 CarbonylContact C-O 3.49Å; N116-I128 WeakPolarHBondContact CA-O 3.48Å; I117-I128 HydrophobicContact CB-CB 4.2Å; I117-I128 HydrophobicContact CG1-CB 4.28Å; I117-I128 PolarHBondContact N-O 3.38Å; I128-F130 HydrophobicContact CG2-CE2 3.9Å; I128-F130 HydrophobicContact CG2-CZ 3.96Å; I128-R458 HydrophobicContact CG2-CB 3.81Å; I128-R458 HydrophobicContact CG2-CG 4.16Å; I128-Q461 HydrophobicContact CD1-CB 3.69Å; I128-Q461 HydrophobicContact CG1-CB 4.35Å; I128-F462 VanDerWaalsContact CD1-CA 3.46Å; I128-F462 HydrophobicContact CD1-CB 3.81Å; I128-M465 HydrophobicContact CD1-CG 4.21Å; I128-M465 HydrophobicContact CD1-SD 3.65Å; I128-M465 HydrophobicContact CG1-SD 4.32Å
129G97Very high95Very high0 Ų026 Ų260%014%0.135CC..EExtended strand (participates in β ladder)trans-132.9146.6177.700000113.6L115 I450 R458L115-G129 CarbonylContact O-C 3.59Å; L115-G129 WeakPolarHBondContact O-CA 3.36Å; G129-I450 PolarHBondContact N-O 3.29Å; G129-R458 WeakPolarHBondContact O-CD 3.49Å; G129-R458 PolarHBondContact O-NH1 3.44Å
130F96.4Very high94.7Very high3 Ų324.5 Ų24.51%0.01313%0.127CC..EExtended strand (participates in β ladder)trans-127.1115.2171.5-56-82.1000108.5G114 L115 I128 I135 F157 T455 R458 I459G114-F130 VanDerWaalsContact CA-O 3.32Å; G114-F130 WeakPolarHBondContact CA-O 3.46Å; L115-F130 HydrophobicContact CB-CB 4.5Å; L115-F130 PolarHBondContact N-O 2.9Å; L115-F130 PolarHBondContact O-N 2.95Å; I128-F130 HydrophobicContact CG2-CE2 3.9Å; I128-F130 HydrophobicContact CG2-CZ 3.96Å; F130-I135 HydrophobicContact CB-CD1 4.14Å; F130-F157 HydrophobicContact CD2-CE1 4.46Å; F130-F157 HydrophobicContact CE2-CD1 4.33Å; F130-F157 HydrophobicContact CE2-CE1 4.26Å; F130-F157 HydrophobicContact CE2-CE2 4.49Å; F130-F157 HydrophobicContact CE2-CZ 4.37Å; F130-T455 HydrophobicContact CD1-CG2 3.97Å; F130-T455 HydrophobicContact CE1-CG2 3.93Å; F130-R458 HydrophobicContact CE1-CB 3.62Å; F130-R458 HydrophobicContact CZ-CB 3.85Å; F130-I459 HydrophobicContact CE1-CG1 3.93Å; F130-I459 HydrophobicContact CZ-CG1 3.87Å
131P95.2Very high94.4Very high3 Ų327.4 Ų27.42%0.01915%0.146CC..EExtended strand (participates in β ladder)trans-66.3154.3173.131.3-35.8000110.3S133 E134P131-S133 WeakPolarHBondContact CB-OG 3.48Å; P131-S133 PolarHBondContact O-N 3.04Å; P131-E134 WeakPolarHBondContact CD-OE1 3.49Å; P131-E134 HydrophobicContact CG-CB 4.18Å; P131-E134 HydrophobicContact CG-CG 3.81Å; P131-E134 WeakPolarHBondContact CG-OE1 3.33Å; P131-E134 PolarHBondContact O-N 3.16Å
132W94.4Very high94.3Very high0 Ų028.4 Ų28.40%014%0.143CC..G310 helixtrans-58.9-28.4175.6-72.1123.5000112.8V110 D111 G114 L115 E134 I135 I138 C174 N177 H178 Y181V110-W132 HydrophobicContact CG1-CH2 4.12Å; V110-W132 HydrophobicContact CG1-CZ2 3.93Å; D111-W132 PolarHBondContact O-NE1 3.1Å; G114-W132 WeakPolarHBondContact O-CZ2 3.45Å; L115-W132 HydrophobicContact CD1-CH2 4.26Å; L115-W132 HydrophobicContact CD1-CZ3 4.09Å; L115-W132 HydrophobicContact CD2-CH2 3.45Å; L115-W132 VanDerWaalsContact CD2-CH2 3.45Å; L115-W132 HydrophobicContact CD2-CZ2 4.05Å; L115-W132 HydrophobicContact CD2-CZ3 4.13Å; L115-W132 HydrophobicContact CG-CH2 3.67Å; L115-W132 HydrophobicContact CG-CZ2 4.32Å; L115-W132 HydrophobicContact CG-CZ3 3.87Å; W132-E134 PolarHBondContact O-N 3.33Å; W132-E134 VanDerWaalsContact O-N 3.14Å; W132-I135 HydrophobicContact CE3-CB 4.45Å; W132-I135 HydrophobicContact CE3-CG1 4.01Å; W132-I135 HydrophobicContact CZ3-CG1 4.42Å; W132-I135 PolarHBondContact O-N 3.46Å; W132-I135 VanDerWaalsContact O-N 3.13Å; W132-I138 HydrophobicContact CZ3-CD1 4.06Å; W132-C174 HydrophobicContact CH2-CB 3.63Å; W132-C174 HydrophobicContact CZ3-CB 4.05Å; W132-N177 HydrophobicContact CZ2-CB 3.81Å; W132-H178 HydrophobicContact CD2-CB 4.1Å; W132-H178 HydrophobicContact CE3-CB 3.95Å; W132-H178 HydrophobicContact CG-CB 4.48Å; W132-H178 HydrophobicContact CZ3-CB 4.48Å; W132-Y181 HydrophobicContact CB-CD1 3.4Å; W132-Y181 VanDerWaalsContact CB-CD1 3.4Å; W132-Y181 HydrophobicContact CB-CD2 3.91Å; W132-Y181 HydrophobicContact CB-CE1 3.57Å; W132-Y181 HydrophobicContact CB-CE2 4.05Å; W132-Y181 HydrophobicContact CB-CG 3.57Å; W132-Y181 AromaticContact CD1-CD2 3.6Å; W132-Y181 AromaticContact CD1-CG 3.72Å; W132-Y181 HydrophobicContact CG-CD1 4.3Å; W132-Y181 HydrophobicContact CG-CD2 4.16Å; W132-Y181 AromaticContact CG-CG 3.99Å; W132-Y181 HydrophobicContact CG-CG 3.99Å
133S91.2Very high94.1Very high20 Ų2033.1 Ų33.114%0.1416%0.163CC..G310 helixtrans-65.9-3172.456.80000115.8P131 I150 Y181 Q391P131-S133 WeakPolarHBondContact CB-OG 3.48Å; P131-S133 PolarHBondContact O-N 3.04Å; S133-I150 WeakPolarHBondContact O-CD1 3.44Å; S133-Y181 PolarHBondContact OG-OH 3.03Å; S133-Q391 VanDerWaalsContact OG-CD 3.32Å; S133-Q391 PolarHBondContact OG-NE2 3.05Å
134E93.1Very high94.1Very high35 Ų3534.3 Ų34.316%0.16417%0.17CC..G310 helixtrans-103.2-3.8171.3-81.2178.3-142.500113.5P131 W132 P149 I150 T455 R458P131-E134 WeakPolarHBondContact CD-OE1 3.49Å; P131-E134 HydrophobicContact CG-CB 4.18Å; P131-E134 HydrophobicContact CG-CG 3.81Å; P131-E134 WeakPolarHBondContact CG-OE1 3.33Å; P131-E134 PolarHBondContact O-N 3.16Å; W132-E134 PolarHBondContact O-N 3.33Å; W132-E134 VanDerWaalsContact O-N 3.14Å; E134-P149 CarbonylContact O-C 3.58Å; E134-P149 VanDerWaalsContact O-CA 3.31Å; E134-P149 WeakPolarHBondContact O-CA 3.48Å; E134-I150 PolarHBondContact O-N 3.41Å; E134-T455 VanDerWaalsContact CD-OG1 3.31Å; E134-T455 WeakPolarHBondContact OE2-CB 3.46Å; E134-T455 WeakPolarHBondContact OE2-CG2 3.43Å; E134-T455 PolarHBondContact OE2-OG1 2.78Å; E134-R458 VanDerWaalsContact CD-NH2 3.32Å; E134-R458 IonicContact OE1-CZ 2.72Å; E134-R458 IonicContact OE1-NH1 3.47Å; E134-R458 PolarHBondContact OE1-NH1 3.24Å; E134-R458 IonicContact OE1-NH2 2.68Å; E134-R458 PolarHBondContact OE1-NH2 2.99Å; E134-R458 IonicContact OE2-CZ 3.79Å; E134-R458 IonicContact OE2-NH1 2.69Å; E134-R458 PolarHBondContact OE2-NH1 3.13Å; E134-R458 IonicContact OE2-NH2 3.19Å; E134-R458 PolarHBondContact OE2-NH2 3.32Å; E134-R458 VanDerWaalsContact OE2-NH2 3.15Å
135I93.3Very high94.1Very high4 Ų434.1 Ų34.12%0.02117%0.169CC..EExtended strand (participates in β ladder)trans-103.9122.5-168.6-49.1-55.1000111.7F130 W132 I138 I147 L381F130-I135 HydrophobicContact CB-CD1 4.14Å; W132-I135 HydrophobicContact CE3-CB 4.45Å; W132-I135 HydrophobicContact CE3-CG1 4.01Å; W132-I135 HydrophobicContact CZ3-CG1 4.42Å; W132-I135 PolarHBondContact O-N 3.46Å; W132-I135 VanDerWaalsContact O-N 3.13Å; I135-I138 HydrophobicContact CG2-CD1 3.92Å; I135-I138 HydrophobicContact CG2-CG1 3.77Å; I135-I147 HydrophobicContact CD1-CG2 3.9Å; I135-I147 HydrophobicContact CG2-CG2 3.74Å; I135-L381 HydrophobicContact CG2-CD1 4.14Å
136R91.1Very high94Very high42 Ų4234.7 Ų34.716%0.15817%0.173CC..EExtended strand (participates in β ladder)trans-92.7-47.8-179.6-171.9178.5-70.8-84.2-0.3113.4K148 P149 I150 L381 T382 D384R136-K148 WeakPolarHBondContact CB-O 3.5Å; R136-K148 PolarHBondContact N-O 3.44Å; R136-P149 WeakPolarHBondContact CB-O 3.19Å; R136-I150 HydrophobicContact CB-CG1 3.92Å; R136-I150 PolarHBondContact NH2-O 3.3Å; R136-L381 PolarHBondContact O-N 3.16Å; R136-T382 WeakPolarHBondContact CA-OG1 3.45Å; R136-T382 PolarHBondContact O-N 2.71Å; R136-D384 IonicContact CZ-OD1 2.86Å; R136-D384 IonicContact NH1-OD1 3.72Å; R136-D384 PolarHBondContact NH1-OD1 3.16Å; R136-D384 VanDerWaalsContact NH1-OD1 3.08Å; R136-D384 IonicContact NH2-OD1 3.25Å
137N89.4Confident94Very high13 Ų1334.2 Ų34.27%0.0717%0.17CC..EExtended strand (participates in β ladder)trans-153.8138.9-168.1-168.3-54.3000109.4K148 E380N137-K148 HydrophobicContact CB-CB 4.2Å; N137-K148 HydrophobicContact CB-CG 4.47Å; N137-K148 PolarHBondContact N-O 2.98Å; N137-K148 PolarHBondContact O-N 3.42Å; N137-E380 PolarHBondContact ND2-OE1 3.26Å
138I93.3Very high93.8Very high3 Ų335 Ų352%0.01517%0.173CC..EExtended strand (participates in β ladder)trans-126.5132179.9-63.6178.3000109.6W132 I135 F145 I147 L171 C174 L381W132-I138 HydrophobicContact CZ3-CD1 4.06Å; I135-I138 HydrophobicContact CG2-CD1 3.92Å; I135-I138 HydrophobicContact CG2-CG1 3.77Å; I138-F145 HydrophobicContact CG2-CD1 4.36Å; I138-F145 HydrophobicContact CG2-CE1 3.28Å; I138-F145 HydrophobicContact CG2-CZ 3.39Å; I138-I147 HydrophobicContact CD1-CD1 4.46Å; I138-I147 HydrophobicContact CG1-CD1 4.47Å; I138-I147 HydrophobicContact CG1-CG1 4.22Å; I138-I147 HydrophobicContact CG1-CG2 4.2Å; I138-I147 HydrophobicContact CG2-CG1 4.35Å; I138-L171 HydrophobicContact CB-CD1 4.21Å; I138-L171 HydrophobicContact CG2-CD1 3.71Å; I138-C174 HydrophobicContact CD1-CB 3.52Å; I138-L381 HydrophobicContact CB-CD1 4.16Å; I138-L381 HydrophobicContact CD1-CD1 3.53Å; I138-L381 HydrophobicContact CG1-CD1 3.59Å
139S91.1Very high93.7Very high45 Ų4535.3 Ų35.332%0.31518%0.175SC..EExtended strand (participates in β ladder)trans-150.3166-179.861.60000111.4V146S139-V146 PolarHBondContact N-O 3.09Å; S139-V146 PolarHBondContact O-N 3.28Å; S139-V146 VanDerWaalsContact O-O 3.07Å; S139-V146 PolarHBondContact OG-O 3.21Å
140F91.4Very high93.4Very high53 Ų5337.6 Ų37.623%0.23219%0.187CC..EExtended strand (participates in β ladder)trans-146.9159.7169.467.9-97.5000111.3K144 F145 L164 N167 K168 L171F140-K144 CarbonylContact C-O 3.4Å; F140-K144 VanDerWaalsContact CA-O 3.23Å; F140-K144 WeakPolarHBondContact CA-O 3.3Å; F140-K144 WeakPolarHBondContact CB-O 3.32Å; F140-F145 HydrophobicContact CB-CB 4.46Å; F140-F145 HydrophobicContact CB-CD2 3.55Å; F140-F145 HydrophobicContact CB-CE2 4.06Å; F140-F145 HydrophobicContact CB-CG 4.19Å; F140-F145 HydrophobicContact CD1-CD2 4.2Å; F140-F145 AromaticContact CD1-CE2 3.88Å; F140-F145 HydrophobicContact CD1-CE2 3.88Å; F140-F145 HydrophobicContact CG-CD2 4.21Å; F140-F145 HydrophobicContact CG-CE2 4.36Å; F140-L164 HydrophobicContact CD2-CD1 4.28Å; F140-L164 HydrophobicContact CE2-CD1 3.66Å; F140-N167 HydrophobicContact CB-CB 4.18Å; F140-N167 HydrophobicContact CD1-CB 3.93Å; F140-N167 HydrophobicContact CD2-CB 3.76Å; F140-N167 HydrophobicContact CE1-CB 4.25Å; F140-N167 HydrophobicContact CE2-CB 4.13Å; F140-N167 HydrophobicContact CG-CB 3.69Å; F140-N167 HydrophobicContact CZ-CB 4.36Å; F140-K168 HydrophobicContact CE1-CG 4.39Å; F140-K168 HydrophobicContact CZ-CG 3.73Å; F140-L171 HydrophobicContact CD1-CB 4.19Å; F140-L171 HydrophobicContact CD1-CD2 4.17Å; F140-L171 HydrophobicContact CE1-CB 3.98Å; F140-L171 HydrophobicContact CE1-CD2 3.7Å; F140-L171 HydrophobicContact CE1-CG 4.46Å
141N90.7Very high93.1Very high133 Ų13340.4 Ų40.471%0.71120%0.202SC*.EExtended strand (participates in β ladder)trans-139.2123.3168.9-172.77.2000109.2K143 K144N141-K143 PolarHBondContact O-N 3.43Å; N141-K143 VanDerWaalsContact O-N 3.08Å; N141-K144 PolarHBondContact N-O 2.92Å; N141-K144 PolarHBondContact O-N 3.39Å
142D91Very high92.8Very high83 Ų8348.1 Ų48.144%0.44424%0.235SC..THydrogen-bonded Turntrans41.8-110.1-164.4178.444.7000112.3N167D142-N167 PolarHBondContact O-ND2 3.03Å
143K93.9Very high92.7Very high104 Ų10457.3 Ų57.345%0.45228%0.275SS..THydrogen-bonded Turntrans-86.3-23.9179.9-70.4164.4-172.8169.80113.6N141 F145 Y160 A161 N167N141-K143 PolarHBondContact O-N 3.43Å; N141-K143 VanDerWaalsContact O-N 3.08Å; K143-F145 PolarHBondContact O-N 2.89Å; K143-Y160 WeakPolarHBondContact O-CA 3.3Å; K143-A161 WeakPolarHBondContact CB-O 3.35Å; K143-A161 WeakPolarHBondContact CG-O 3.48Å; K143-A161 PolarHBondContact O-N 2.63Å; K143-N167 WeakPolarHBondContact CA-ND2 3.31Å; K143-N167 PolarHBondContact O-ND2 3.48Å
144K95.7Very high92.8Very high88 Ų8856.9 Ų56.938%0.38327%0.272SS..EExtended strand (participates in β ladder)trans-80.1115.5-175.2-176-172.5178.5-173.10110.5F140 N141 V146 I158 Y160F140-K144 CarbonylContact C-O 3.4Å; F140-K144 VanDerWaalsContact CA-O 3.23Å; F140-K144 WeakPolarHBondContact CA-O 3.3Å; F140-K144 WeakPolarHBondContact CB-O 3.32Å; N141-K144 PolarHBondContact N-O 2.92Å; N141-K144 PolarHBondContact O-N 3.39Å; K144-V146 HydrophobicContact CD-CG2 4.23Å; K144-V146 HydrophobicContact CG-CG2 4.1Å; K144-I158 HydrophobicContact CD-CG2 4.43Å; K144-I158 HydrophobicContact CG-CG2 3.98Å; K144-Y160 HydrophobicContact CB-CD1 4.02Å; K144-Y160 HydrophobicContact CB-CE1 3.85Å; K144-Y160 HydrophobicContact CD-CE1 4.41Å; K144-Y160 HydrophobicContact CG-CD1 4.34Å; K144-Y160 HydrophobicContact CG-CE1 3.82Å
145F97.2Very high92.9Very high0 Ų062.5 Ų62.50%029%0.292CS..EExtended strand (participates in β ladder)trans-95.1142.7171.6-148.9-93.2000109.8I138 F140 K143 I147 I158 F159 N167 I170 L171I138-F145 HydrophobicContact CG2-CD1 4.36Å; I138-F145 HydrophobicContact CG2-CE1 3.28Å; I138-F145 HydrophobicContact CG2-CZ 3.39Å; F140-F145 HydrophobicContact CB-CB 4.46Å; F140-F145 HydrophobicContact CB-CD2 3.55Å; F140-F145 HydrophobicContact CB-CE2 4.06Å; F140-F145 HydrophobicContact CB-CG 4.19Å; F140-F145 HydrophobicContact CD1-CD2 4.2Å; F140-F145 AromaticContact CD1-CE2 3.88Å; F140-F145 HydrophobicContact CD1-CE2 3.88Å; F140-F145 HydrophobicContact CG-CD2 4.21Å; F140-F145 HydrophobicContact CG-CE2 4.36Å; K143-F145 PolarHBondContact O-N 2.89Å; F145-I147 HydrophobicContact CD1-CD1 4.03Å; F145-I147 HydrophobicContact CD1-CG1 3.75Å; F145-I147 HydrophobicContact CE1-CD1 3.81Å; F145-I147 HydrophobicContact CE1-CG1 3.76Å; F145-I158 WeakPolarHBondContact O-CA 3.35Å; F145-F159 HydrophobicContact CB-CD1 4.27Å; F145-F159 HydrophobicContact CB-CD2 3.72Å; F145-F159 HydrophobicContact CB-CE1 3.96Å; F145-F159 HydrophobicContact CB-CE2 3.35Å; F145-F159 HydrophobicContact CB-CG 4.17Å; F145-F159 HydrophobicContact CB-CZ 3.48Å; F145-F159 VanDerWaalsContact CB-CZ 3.48Å; F145-F159 HydrophobicContact CD1-CD1 4.42Å; F145-F159 AromaticContact CD1-CE1 3.45Å; F145-F159 HydrophobicContact CD1-CE1 3.45Å; F145-F159 VanDerWaalsContact CD1-CE1 3.45Å; F145-F159 AromaticContact CD1-CE2 3.94Å; F145-F159 HydrophobicContact CD1-CE2 3.94Å; F145-F159 AromaticContact CD1-CZ 3.14Å; F145-F159 HydrophobicContact CD1-CZ 3.14Å; F145-F159 HydrophobicContact CD2-CE2 4.27Å; F145-F159 HydrophobicContact CD2-CZ 4.14Å; F145-F159 HydrophobicContact CE1-CE1 4.21Å; F145-F159 AromaticContact CE1-CZ 3.81Å; F145-F159 HydrophobicContact CE1-CZ 3.81Å; F145-F159 HydrophobicContact CG-CD2 4.45Å; F145-F159 AromaticContact CG-CE1 3.97Å; F145-F159 HydrophobicContact CG-CE1 3.97Å; F145-F159 AromaticContact CG-CE2 3.62Å; F145-F159 HydrophobicContact CG-CE2 3.62Å; F145-F159 AromaticContact CG-CZ 3.33Å; F145-F159 HydrophobicContact CG-CZ 3.33Å; F145-F159 PolarHBondContact N-O 3.29Å; F145-F159 PolarHBondContact O-N 2.75Å; F145-N167 HydrophobicContact CD2-CB 4.04Å; F145-N167 WeakPolarHBondContact CD2-OD1 3Å; F145-N167 HydrophobicContact CE2-CB 4.36Å; F145-I170 HydrophobicContact CD2-CG2 4.46Å; F145-I170 HydrophobicContact CE1-CG2 3.93Å; F145-I170 HydrophobicContact CE2-CB 3.91Å; F145-I170 HydrophobicContact CE2-CG2 3.73Å; F145-I170 HydrophobicContact CZ-CB 4.07Å; F145-I170 HydrophobicContact CZ-CG2 3.42Å; F145-I170 VanDerWaalsContact CZ-CG2 3.42Å; F145-L171 HydrophobicContact CE2-CB 4.37Å; F145-L171 HydrophobicContact CZ-CB 4.4Å
146V96.7Very high93.1Very high19 Ų1964.7 Ų64.712%0.11530%0.304CS..EExtended strand (participates in β ladder)trans-138.4118-174.9-174.20000109.7S139 K144 D156 I158S139-V146 PolarHBondContact N-O 3.09Å; S139-V146 PolarHBondContact O-N 3.28Å; S139-V146 VanDerWaalsContact O-O 3.07Å; S139-V146 PolarHBondContact OG-O 3.21Å; K144-V146 HydrophobicContact CD-CG2 4.23Å; K144-V146 HydrophobicContact CG-CG2 4.1Å; V146-D156 HydrophobicContact CG1-CB 4.03Å; V146-D156 WeakPolarHBondContact CG1-OD2 3.4Å; V146-I158 HydrophobicContact CG1-CG1 4.23Å; V146-I158 HydrophobicContact CG2-CG1 4.3Å
147I96.3Very high93.4Very high1 Ų163 Ų631%0.00530%0.298CS..EExtended strand (participates in β ladder)trans-116120.3179.3-58-167.5000108L115 I135 I138 F145 F157 F159L115-I147 HydrophobicContact CD1-CD1 3.38Å; I135-I147 HydrophobicContact CD1-CG2 3.9Å; I135-I147 HydrophobicContact CG2-CG2 3.74Å; I138-I147 HydrophobicContact CD1-CD1 4.46Å; I138-I147 HydrophobicContact CG1-CD1 4.47Å; I138-I147 HydrophobicContact CG1-CG1 4.22Å; I138-I147 HydrophobicContact CG1-CG2 4.2Å; I138-I147 HydrophobicContact CG2-CG1 4.35Å; F145-I147 HydrophobicContact CD1-CD1 4.03Å; F145-I147 HydrophobicContact CD1-CG1 3.75Å; F145-I147 HydrophobicContact CE1-CD1 3.81Å; F145-I147 HydrophobicContact CE1-CG1 3.76Å; I147-F157 HydrophobicContact CB-CB 4.21Å; I147-F157 HydrophobicContact CB-CD1 3.93Å; I147-F157 HydrophobicContact CD1-CD1 3.94Å; I147-F157 HydrophobicContact CD1-CE1 4.08Å; I147-F157 HydrophobicContact CG1-CD1 4.23Å; I147-F157 HydrophobicContact CG2-CD1 4.34Å; I147-F157 PolarHBondContact N-O 2.86Å; I147-F157 PolarHBondContact O-N 2.92Å; I147-F159 HydrophobicContact CD1-CE1 3.98Å; I147-F159 HydrophobicContact CG1-CE1 4.44Å
148K94.4Very high93.8Very high82 Ų8263.1 Ų63.136%0.35730%0.298SS..EExtended strand (participates in β ladder)trans-94126.6178.7-57.3-165.3164.5-79.20110R136 N137 D156R136-K148 WeakPolarHBondContact CB-O 3.5Å; R136-K148 PolarHBondContact N-O 3.44Å; N137-K148 HydrophobicContact CB-CB 4.2Å; N137-K148 HydrophobicContact CB-CG 4.47Å; N137-K148 PolarHBondContact N-O 2.98Å; N137-K148 PolarHBondContact O-N 3.42Å; K148-D156 WeakPolarHBondContact CG-OD1 3.3Å; K148-D156 IonicContact NZ-OD1 2.58Å; K148-D156 PolarHBondContact NZ-OD1 2.86Å; K148-D156 IonicContact NZ-OD2 3.23Å; K148-D156 PolarHBondContact NZ-OD2 2.63Å
149P94.2Very high94Very high11 Ų1163 Ų637%0.07130%0.298CS..EExtended strand (participates in β ladder)trans-71.1162175.129.8-34.6000112.3E134 R136 T455E134-P149 CarbonylContact O-C 3.58Å; E134-P149 VanDerWaalsContact O-CA 3.31Å; E134-P149 WeakPolarHBondContact O-CA 3.48Å; R136-P149 WeakPolarHBondContact CB-O 3.19Å; P149-T455 HydrophobicContact CB-CG2 3.86Å
150I91.1Very high94.3Very high47 Ų4764.9 Ų64.924%0.24130%0.299CS..SBendtrans-69.1-37.7170.3-67.2-177.6000110.7S133 E134 R136 K152 T382S133-I150 WeakPolarHBondContact O-CD1 3.44Å; E134-I150 PolarHBondContact O-N 3.41Å; R136-I150 HydrophobicContact CB-CG1 3.92Å; R136-I150 PolarHBondContact NH2-O 3.3Å; I150-K152 PolarHBondContact O-N 2.76Å; I150-K152 VanDerWaalsContact O-N 3.12Å; I150-T382 HydrophobicContact CD1-CG2 3.87Å; I150-T382 WeakPolarHBondContact CD1-OG1 3.28Å
151D90.2Very high94.5Very high62 Ų6262.5 Ų62.533%0.33229%0.288SS..SBendtrans-66.1106.4170.8172.529.8000111K153 S154D151-K153 PolarHBondContact O-N 3.19Å; D151-K153 VanDerWaalsContact O-N 3.13Å; D151-K153 WeakPolarHBondContact OD1-CB 3.18Å; D151-K153 PolarHBondContact OD1-N 2.79Å; D151-S154 PolarHBondContact O-N 3.18Å; D151-S154 VanDerWaalsContact O-N 3.11Å; D151-S154 WeakPolarHBondContact OD2-CB 3.39Å; D151-S154 PolarHBondContact OD2-N 2.88Å; D151-S154 VanDerWaalsContact OD2-N 3.1Å; D151-S154 PolarHBondContact OD2-OG 3.43Å
152K89.5Confident94.7Very high165 Ų16559.1 Ų59.172%0.71727%0.274SS*.THydrogen-bonded Turntrans-67-8.1179-59.5178.1-176.3173.10113.5I150I150-K152 PolarHBondContact O-N 2.76Å; I150-K152 VanDerWaalsContact O-N 3.12Å
153K92.1Very high94.7Very high193 Ų19362.3 Ų62.384%0.83928%0.28SS*.THydrogen-bonded Turntrans-89.4-23.8173.3-57.8177.8-178.9177.50112.8D151D151-K153 PolarHBondContact O-N 3.19Å; D151-K153 VanDerWaalsContact O-N 3.13Å; D151-K153 WeakPolarHBondContact OD1-CB 3.18Å; D151-K153 PolarHBondContact OD1-N 2.79Å
154S93.2Very high94.4Very high11 Ų1161.4 Ų61.48%0.07728%0.279CS..SBendtrans-77.4145.2176.1-69.50000110.8D151 Q456D151-S154 PolarHBondContact O-N 3.18Å; D151-S154 VanDerWaalsContact O-N 3.11Å; D151-S154 WeakPolarHBondContact OD2-CB 3.39Å; D151-S154 PolarHBondContact OD2-N 2.88Å; D151-S154 VanDerWaalsContact OD2-N 3.1Å; D151-S154 PolarHBondContact OD2-OG 3.43Å; S154-Q456 WeakPolarHBondContact OG-CB 3.4Å; S154-Q456 PolarHBondContact OG-N 3.28Å; S154-Q456 VanDerWaalsContact OG-N 3.1Å
155R95.3Very high94.2Very high153 Ų15365.9 Ų65.958%0.57729%0.294SS*.PPolyproline II helixtrans-69.9158.7177.2-62.5-169.6-75.4173.70.1111F157 Q456 I459 D460R155-F157 PolarHBondContact O-N 3.47Å; R155-Q456 VanDerWaalsContact NE-NE2 3.17Å; R155-I459 WeakPolarHBondContact O-CD1 3.23Å; R155-D460 IonicContact CZ-OD1 3.16Å; R155-D460 IonicContact NE-OD1 3.31Å; R155-D460 IonicContact NH2-OD1 3.42Å; R155-D460 PolarHBondContact NH2-OD1 3.16Å
156D96.3Very high93.9Very high51 Ų5167.4 Ų67.427%0.27330%0.302SS..PPolyproline II helixtrans-60130.1170.4-73.2-4.2000110.4V146 K148 I158V146-D156 HydrophobicContact CG1-CB 4.03Å; V146-D156 WeakPolarHBondContact CG1-OD2 3.4Å; K148-D156 WeakPolarHBondContact CG-OD1 3.3Å; K148-D156 IonicContact NZ-OD1 2.58Å; K148-D156 PolarHBondContact NZ-OD1 2.86Å; K148-D156 IonicContact NZ-OD2 3.23Å; K148-D156 PolarHBondContact NZ-OD2 2.63Å; D156-I158 HydrophobicContact CB-CD1 4.04Å; D156-I158 HydrophobicContact CB-CG1 3.98Å
157F97.6Very high93.6Very high5 Ų566.5 Ų66.52%0.02230%0.296CS..EExtended strand (participates in β ladder)trans-76.7120.8168.4171.6-134.1000108.5I117 F130 I147 R155 F159 I459 F462I117-F157 HydrophobicContact CD1-CZ 3.77Å; I117-F157 HydrophobicContact CG1-CZ 4.5Å; F130-F157 HydrophobicContact CD2-CE1 4.46Å; F130-F157 HydrophobicContact CE2-CD1 4.33Å; F130-F157 HydrophobicContact CE2-CE1 4.26Å; F130-F157 HydrophobicContact CE2-CE2 4.49Å; F130-F157 HydrophobicContact CE2-CZ 4.37Å; I147-F157 HydrophobicContact CB-CB 4.21Å; I147-F157 HydrophobicContact CB-CD1 3.93Å; I147-F157 HydrophobicContact CD1-CD1 3.94Å; I147-F157 HydrophobicContact CD1-CE1 4.08Å; I147-F157 HydrophobicContact CG1-CD1 4.23Å; I147-F157 HydrophobicContact CG2-CD1 4.34Å; I147-F157 PolarHBondContact N-O 2.86Å; I147-F157 PolarHBondContact O-N 2.92Å; R155-F157 PolarHBondContact O-N 3.47Å; F157-F159 AromaticContact CE1-CD1 3.88Å; F157-F159 HydrophobicContact CE1-CD1 3.88Å; F157-F159 HydrophobicContact CE1-CE1 4.02Å; F157-F159 HydrophobicContact CE2-CD1 4.29Å; F157-F159 AromaticContact CZ-CD1 3.68Å; F157-F159 HydrophobicContact CZ-CD1 3.68Å; F157-F159 HydrophobicContact CZ-CE1 4.24Å; F157-I459 HydrophobicContact CB-CD1 3.84Å; F157-I459 HydrophobicContact CB-CG1 4.01Å; F157-F462 HydrophobicContact CD2-CD1 4.08Å; F157-F462 HydrophobicContact CD2-CE1 4.32Å; F157-F462 HydrophobicContact CD2-CG 4.4Å; F157-F462 HydrophobicContact CE2-CB 4.48Å; F157-F462 AromaticContact CE2-CD1 3.61Å; F157-F462 HydrophobicContact CE2-CD1 3.61Å; F157-F462 AromaticContact CE2-CD2 3.86Å; F157-F462 HydrophobicContact CE2-CD2 3.86Å; F157-F462 AromaticContact CE2-CE1 3.68Å; F157-F462 HydrophobicContact CE2-CE1 3.68Å; F157-F462 AromaticContact CE2-CE2 3.92Å; F157-F462 HydrophobicContact CE2-CE2 3.92Å; F157-F462 AromaticContact CE2-CG 3.7Å; F157-F462 HydrophobicContact CE2-CG 3.7Å; F157-F462 AromaticContact CE2-CZ 3.83Å; F157-F462 HydrophobicContact CE2-CZ 3.83Å; F157-F462 HydrophobicContact CZ-CD2 4.43Å; F157-F462 HydrophobicContact CZ-CE2 4.31Å; F157-F462 HydrophobicContact CZ-CZ 4.43Å
158I97.6Very high93.3Very high17 Ų1773 Ų739%0.08732%0.324CS..EExtended strand (participates in β ladder)trans-132.3128.7-169.7-64172.6000109.5K144 F145 V146 D156 Y160 F462K144-I158 HydrophobicContact CD-CG2 4.43Å; K144-I158 HydrophobicContact CG-CG2 3.98Å; F145-I158 WeakPolarHBondContact O-CA 3.35Å; V146-I158 HydrophobicContact CG1-CG1 4.23Å; V146-I158 HydrophobicContact CG2-CG1 4.3Å; D156-I158 HydrophobicContact CB-CD1 4.04Å; D156-I158 HydrophobicContact CB-CG1 3.98Å; I158-Y160 HydrophobicContact CG2-CE2 4.29Å; I158-F462 WeakPolarHBondContact O-CE1 3.47Å
159F98.1Very high93.2Very high0 Ų076 Ų760%033%0.333CS..EExtended strand (participates in β ladder)trans-139.2171.2172.863.6-98.4000111I98 R99 L108 F145 I147 F157 I170 F462I98-F159 HydrophobicContact CB-CB 4.42Å; I98-F159 HydrophobicContact CB-CD2 3.83Å; I98-F159 HydrophobicContact CB-CE2 4.5Å; I98-F159 HydrophobicContact CB-CG 4.37Å; I98-F159 HydrophobicContact CD1-CB 3.91Å; I98-F159 HydrophobicContact CD1-CD1 4.48Å; I98-F159 HydrophobicContact CD1-CD2 4.2Å; I98-F159 HydrophobicContact CD1-CG 3.97Å; I98-F159 HydrophobicContact CG2-CD2 3.43Å; I98-F159 VanDerWaalsContact CG2-CD2 3.43Å; I98-F159 HydrophobicContact CG2-CE2 3.62Å; I98-F159 HydrophobicContact CG2-CG 4.31Å; R99-F159 CarbonylContact O-C 3.6Å; R99-F159 WeakPolarHBondContact O-CA 3.11Å; R99-F159 WeakPolarHBondContact O-CB 3.47Å; L108-F159 HydrophobicContact CD2-CE1 3.98Å; L108-F159 HydrophobicContact CD2-CE2 4.04Å; L108-F159 HydrophobicContact CD2-CZ 3.47Å; L108-F159 VanDerWaalsContact CD2-CZ 3.47Å; F145-F159 HydrophobicContact CB-CD1 4.27Å; F145-F159 HydrophobicContact CB-CD2 3.72Å; F145-F159 HydrophobicContact CB-CE1 3.96Å; F145-F159 HydrophobicContact CB-CE2 3.35Å; F145-F159 HydrophobicContact CB-CG 4.17Å; F145-F159 HydrophobicContact CB-CZ 3.48Å; F145-F159 VanDerWaalsContact CB-CZ 3.48Å; F145-F159 HydrophobicContact CD1-CD1 4.42Å; F145-F159 AromaticContact CD1-CE1 3.45Å; F145-F159 HydrophobicContact CD1-CE1 3.45Å; F145-F159 VanDerWaalsContact CD1-CE1 3.45Å; F145-F159 AromaticContact CD1-CE2 3.94Å; F145-F159 HydrophobicContact CD1-CE2 3.94Å; F145-F159 AromaticContact CD1-CZ 3.14Å; F145-F159 HydrophobicContact CD1-CZ 3.14Å; F145-F159 HydrophobicContact CD2-CE2 4.27Å; F145-F159 HydrophobicContact CD2-CZ 4.14Å; F145-F159 HydrophobicContact CE1-CE1 4.21Å; F145-F159 AromaticContact CE1-CZ 3.81Å; F145-F159 HydrophobicContact CE1-CZ 3.81Å; F145-F159 HydrophobicContact CG-CD2 4.45Å; F145-F159 AromaticContact CG-CE1 3.97Å; F145-F159 HydrophobicContact CG-CE1 3.97Å; F145-F159 AromaticContact CG-CE2 3.62Å; F145-F159 HydrophobicContact CG-CE2 3.62Å; F145-F159 AromaticContact CG-CZ 3.33Å; F145-F159 HydrophobicContact CG-CZ 3.33Å; F145-F159 PolarHBondContact N-O 3.29Å; F145-F159 PolarHBondContact O-N 2.75Å; I147-F159 HydrophobicContact CD1-CE1 3.98Å; I147-F159 HydrophobicContact CG1-CE1 4.44Å; F157-F159 AromaticContact CE1-CD1 3.88Å; F157-F159 HydrophobicContact CE1-CD1 3.88Å; F157-F159 HydrophobicContact CE1-CE1 4.02Å; F157-F159 HydrophobicContact CE2-CD1 4.29Å; F157-F159 AromaticContact CZ-CD1 3.68Å; F157-F159 HydrophobicContact CZ-CD1 3.68Å; F157-F159 HydrophobicContact CZ-CE1 4.24Å; F159-I170 HydrophobicContact CE2-CD1 4.06Å; F159-I170 HydrophobicContact CZ-CD1 4.42Å; F159-I170 HydrophobicContact CZ-CG2 4.37Å; F159-F462 HydrophobicContact CB-CE1 4.4Å; F159-F462 HydrophobicContact CB-CZ 3.82Å
160Y98.1Very high93.2Very high85 Ų8575.4 Ų75.433%0.33333%0.33SS..EExtended strand (participates in β ladder)trans-124.4122-177.5-56.7-92.4000110.4I98 R99 K101 K143 K144 I158I98-Y160 CarbonylContact C-O 3.59Å; I98-Y160 WeakPolarHBondContact CA-O 3.06Å; R99-Y160 PolarHBondContact N-O 3.5Å; R99-Y160 PolarHBondContact O-N 3.13Å; K101-Y160 HydrophobicContact CG-CE2 4.13Å; K143-Y160 WeakPolarHBondContact O-CA 3.3Å; K144-Y160 HydrophobicContact CB-CD1 4.02Å; K144-Y160 HydrophobicContact CB-CE1 3.85Å; K144-Y160 HydrophobicContact CD-CE1 4.41Å; K144-Y160 HydrophobicContact CG-CD1 4.34Å; K144-Y160 HydrophobicContact CG-CE1 3.82Å; I158-Y160 HydrophobicContact CG2-CE2 4.29Å
161A96.3Very high93.3Very high2 Ų274.2 Ų74.22%0.01732%0.324CS..  trans-96.7149170.800000110.3K143 R163 I166 N167 I170K143-A161 WeakPolarHBondContact CB-O 3.35Å; K143-A161 WeakPolarHBondContact CG-O 3.48Å; K143-A161 PolarHBondContact O-N 2.63Å; A161-R163 VanDerWaalsContact C-N 3.31Å; A161-R163 PolarHBondContact O-N 2.9Å; A161-I166 HydrophobicContact CB-CB 4.32Å; A161-I166 HydrophobicContact CB-CG2 3.89Å; A161-N167 WeakPolarHBondContact CB-OD1 3.31Å; A161-I170 HydrophobicContact CB-CD1 4.49Å
162P93.8Very high93.3Very high63 Ų6373.9 Ų73.941%0.40933%0.33SS..SBendtrans-72.2-17.2-170.625.2-33000115E97 I166E97-P162 VanDerWaalsContact O-CD 3.27Å; E97-P162 WeakPolarHBondContact O-CD 3.33Å; P162-I166 HydrophobicContact CG-CD1 3.88Å
163R90.8Very high93.5Very high150 Ų15068.1 Ų68.157%0.56631%0.307SS*.SBendtrans-144.5137.5-176-52.1-174.7-169-166.14.3112A161 R165 I166A161-R163 VanDerWaalsContact C-N 3.31Å; A161-R163 PolarHBondContact O-N 2.9Å; R163-R165 HydrophobicContact CB-CG 4.26Å; R163-R165 PolarHBondContact O-N 3.13Å; R163-R165 VanDerWaalsContact O-N 3.11Å; R163-I166 HydrophobicContact CB-CD1 4.07Å; R163-I166 HydrophobicContact CB-CG1 4.38Å; R163-I166 HydrophobicContact CG-CD1 4.33Å; R163-I166 VanDerWaalsContact O-CB 3.29Å; R163-I166 WeakPolarHBondContact O-CB 3.34Å; R163-I166 PolarHBondContact O-N 2.82Å
164L87.7Confident93.6Very high85 Ų8559 Ų5945%0.44527%0.267SS..Hα-helixtrans-47.7-41.4176.6-178.567.7000114.1F140 I166 N167 K168F140-L164 HydrophobicContact CD2-CD1 4.28Å; F140-L164 HydrophobicContact CE2-CD1 3.66Å; L164-I166 PolarHBondContact O-N 2.7Å; L164-N167 PolarHBondContact O-N 2.99Å; L164-N167 VanDerWaalsContact O-N 3.16Å; L164-K168 PolarHBondContact O-N 3.17Å; L164-K168 VanDerWaalsContact O-N 3.12Å
165R90.9Very high93.5Very high181 Ų18159.3 Ų59.368%0.68327%0.267SS*.Hα-helixtrans-60.2-27.6178.576.6-179.6-168.7176.65.6113.7R163 R169R163-R165 HydrophobicContact CB-CG 4.26Å; R163-R165 PolarHBondContact O-N 3.13Å; R163-R165 VanDerWaalsContact O-N 3.11Å; R165-R169 PolarHBondContact O-N 3.33Å
166I91.8Very high93.2Very high33 Ų3353.4 Ų53.417%0.16925%0.254CS..Hα-helixtrans-73.9-46.8177.4-67166.8000109.2F96 A161 P162 R163 L164 K168 R169 I170F96-I166 HydrophobicContact CD1-CG2 3.55Å; F96-I166 HydrophobicContact CE1-CG2 4.02Å; F96-I166 HydrophobicContact CG-CG2 4.48Å; A161-I166 HydrophobicContact CB-CB 4.32Å; A161-I166 HydrophobicContact CB-CG2 3.89Å; P162-I166 HydrophobicContact CG-CD1 3.88Å; R163-I166 HydrophobicContact CB-CD1 4.07Å; R163-I166 HydrophobicContact CB-CG1 4.38Å; R163-I166 HydrophobicContact CG-CD1 4.33Å; R163-I166 VanDerWaalsContact O-CB 3.29Å; R163-I166 WeakPolarHBondContact O-CB 3.34Å; R163-I166 PolarHBondContact O-N 2.82Å; L164-I166 PolarHBondContact O-N 2.7Å; I166-K168 VanDerWaalsContact C-N 3.3Å; I166-K168 PolarHBondContact O-N 2.88Å; I166-R169 PolarHBondContact O-N 3.34Å; I166-I170 HydrophobicContact CG2-CD1 3.73Å; I166-I170 HydrophobicContact CG2-CG1 4.18Å; I166-I170 WeakPolarHBondContact O-CG1 3.36Å; I166-I170 PolarHBondContact O-N 3.37Å
167N89.8Confident93.1Very high0 Ų052.2 Ų52.20%025%0.248CC..Hα-helixtrans-58.8-38.9176.5-76.7-18.3000112.7F140 D142 K143 F145 A161 L164 R169 I170 L171F140-N167 HydrophobicContact CB-CB 4.18Å; F140-N167 HydrophobicContact CD1-CB 3.93Å; F140-N167 HydrophobicContact CD2-CB 3.76Å; F140-N167 HydrophobicContact CE1-CB 4.25Å; F140-N167 HydrophobicContact CE2-CB 4.13Å; F140-N167 HydrophobicContact CG-CB 3.69Å; F140-N167 HydrophobicContact CZ-CB 4.36Å; D142-N167 PolarHBondContact O-ND2 3.03Å; K143-N167 WeakPolarHBondContact CA-ND2 3.31Å; K143-N167 PolarHBondContact O-ND2 3.48Å; F145-N167 HydrophobicContact CD2-CB 4.04Å; F145-N167 WeakPolarHBondContact CD2-OD1 3Å; F145-N167 HydrophobicContact CE2-CB 4.36Å; A161-N167 WeakPolarHBondContact CB-OD1 3.31Å; L164-N167 PolarHBondContact O-N 2.99Å; L164-N167 VanDerWaalsContact O-N 3.16Å; N167-R169 PolarHBondContact O-N 2.91Å; N167-I170 PolarHBondContact O-N 2.93Å; N167-L171 WeakPolarHBondContact O-CB 3.09Å; N167-L171 PolarHBondContact O-N 3.33Å
168K90.2Very high92.8Very high137 Ų13752.2 Ų52.260%0.59625%0.248SC*.Hα-helixtrans-57.9-45.7170.2-77.6-163.4171.8-156.30112.8F140 L164 I166 L171 A172F140-K168 HydrophobicContact CE1-CG 4.39Å; F140-K168 HydrophobicContact CZ-CG 3.73Å; L164-K168 PolarHBondContact O-N 3.17Å; L164-K168 VanDerWaalsContact O-N 3.12Å; I166-K168 VanDerWaalsContact C-N 3.3Å; I166-K168 PolarHBondContact O-N 2.88Å; K168-L171 PolarHBondContact O-N 3.4Å; K168-A172 PolarHBondContact O-N 2.82Å
169R92.7Very high92.4Very high144 Ų14457.7 Ų57.754%0.54327%0.273SS..Hα-helixtrans-69.3-37.3179.3-162.3178.477.3178.73.1112.5F96 R165 I166 N167 L173F96-R169 HydrophobicContact CE1-CB 4.19Å; F96-R169 HydrophobicContact CE1-CG 4.37Å; F96-R169 HydrophobicContact CZ-CB 4.26Å; F96-R169 HydrophobicContact CZ-CG 4.12Å; F96-R169 VanDerWaalsContact CZ-NE 3.33Å; R165-R169 PolarHBondContact O-N 3.33Å; I166-R169 PolarHBondContact O-N 3.34Å; N167-R169 PolarHBondContact O-N 2.91Å; R169-L173 HydrophobicContact CG-CD1 4.34Å; R169-L173 WeakPolarHBondContact O-CG 3.45Å; R169-L173 PolarHBondContact O-N 3.32Å
170I94.6Very high92Very high0 Ų061.4 Ų61.40%029%0.292CS..Hα-helixtrans-61.6-51.6173.5-64169.5000109.5F96 L108 V110 F145 F159 A161 I166 N167 A172 L173 C174F96-I170 HydrophobicContact CB-CD1 4.09Å; F96-I170 HydrophobicContact CB-CG1 4.35Å; F96-I170 HydrophobicContact CD1-CD1 4.02Å; F96-I170 HydrophobicContact CD1-CG1 3.64Å; F96-I170 HydrophobicContact CD2-CD1 4.38Å; F96-I170 HydrophobicContact CD2-CG1 3.74Å; F96-I170 HydrophobicContact CE1-CD1 4.44Å; F96-I170 HydrophobicContact CE1-CG1 3.6Å; F96-I170 HydrophobicContact CE2-CG1 3.75Å; F96-I170 HydrophobicContact CG-CD1 3.93Å; F96-I170 HydrophobicContact CG-CG1 3.66Å; F96-I170 HydrophobicContact CZ-CG1 3.65Å; L108-I170 HydrophobicContact CD2-CD1 4.23Å; L108-I170 HydrophobicContact CD2-CG2 3.96Å; V110-I170 HydrophobicContact CG2-CG2 4.4Å; F145-I170 HydrophobicContact CD2-CG2 4.46Å; F145-I170 HydrophobicContact CE1-CG2 3.93Å; F145-I170 HydrophobicContact CE2-CB 3.91Å; F145-I170 HydrophobicContact CE2-CG2 3.73Å; F145-I170 HydrophobicContact CZ-CB 4.07Å; F145-I170 HydrophobicContact CZ-CG2 3.42Å; F145-I170 VanDerWaalsContact CZ-CG2 3.42Å; F159-I170 HydrophobicContact CE2-CD1 4.06Å; F159-I170 HydrophobicContact CZ-CD1 4.42Å; F159-I170 HydrophobicContact CZ-CG2 4.37Å; A161-I170 HydrophobicContact CB-CD1 4.49Å; I166-I170 HydrophobicContact CG2-CD1 3.73Å; I166-I170 HydrophobicContact CG2-CG1 4.18Å; I166-I170 WeakPolarHBondContact O-CG1 3.36Å; I166-I170 PolarHBondContact O-N 3.37Å; N167-I170 PolarHBondContact O-N 2.93Å; I170-A172 PolarHBondContact O-N 3.5Å; I170-L173 PolarHBondContact O-N 2.81Å; I170-C174 WeakPolarHBondContact O-CB 3.35Å; I170-C174 PolarHBondContact O-N 3.38Å; I170-C174 PolarHBondContact O-SG 3.42Å
171L92.7Very high91.7Very high22 Ų2257.4 Ų57.412%0.11528%0.277CS..Hα-helixtrans-54.9-50.8-178.8178.364.8000112.1I138 F140 F145 N167 K168 L173 C174 M175I138-L171 HydrophobicContact CB-CD1 4.21Å; I138-L171 HydrophobicContact CG2-CD1 3.71Å; F140-L171 HydrophobicContact CD1-CB 4.19Å; F140-L171 HydrophobicContact CD1-CD2 4.17Å; F140-L171 HydrophobicContact CE1-CB 3.98Å; F140-L171 HydrophobicContact CE1-CD2 3.7Å; F140-L171 HydrophobicContact CE1-CG 4.46Å; F145-L171 HydrophobicContact CE2-CB 4.37Å; F145-L171 HydrophobicContact CZ-CB 4.4Å; N167-L171 WeakPolarHBondContact O-CB 3.09Å; N167-L171 PolarHBondContact O-N 3.33Å; K168-L171 PolarHBondContact O-N 3.4Å; L171-L173 PolarHBondContact O-N 3.15Å; L171-C174 PolarHBondContact O-N 3Å; L171-M175 HydrophobicContact CD1-CG 4.24Å; L171-M175 HydrophobicContact CD1-SD 4.04Å; L171-M175 HydrophobicContact CG-SD 3.97Å; L171-M175 WeakPolarHBondContact O-CB 3.33Å; L171-M175 WeakPolarHBondContact O-CG 3.49Å; L171-M175 PolarHBondContact O-N 3.12Å
172A90Very high91.3Very high55 Ų5557.6 Ų57.646%0.45528%0.277SS..Hα-helixtrans-60.8-42.8-179.600000112.7K168 I170 G176K168-A172 PolarHBondContact O-N 2.82Å; I170-A172 PolarHBondContact O-N 3.5Å; A172-G176 PolarHBondContact O-N 2.87Å
173L94.3Very high91Very high44 Ų4460.6 Ų60.623%0.2328%0.281CS..Hα-helixtrans-67.8-41.3176.5-72.9174.1000112.4N94 F96 V110 R169 I170 L171 M175 N177N94-L173 HydrophobicContact CB-CD1 3.74Å; F96-L173 HydrophobicContact CE2-CD1 3.84Å; F96-L173 HydrophobicContact CZ-CD1 3.74Å; V110-L173 HydrophobicContact CG1-CB 4.05Å; R169-L173 HydrophobicContact CG-CD1 4.34Å; R169-L173 WeakPolarHBondContact O-CG 3.45Å; R169-L173 PolarHBondContact O-N 3.32Å; I170-L173 PolarHBondContact O-N 2.81Å; L171-L173 PolarHBondContact O-N 3.15Å; L173-M175 VanDerWaalsContact C-N 3.34Å; L173-N177 VanDerWaalsContact O-CB 3.32Å; L173-N177 WeakPolarHBondContact O-CB 3.34Å; L173-N177 PolarHBondContact O-N 2.68Å; L173-N177 PolarHBondContact O-ND2 2.66Å
174C94.8Very high90.9Very high0 Ų058.9 Ų58.90%027%0.274CS..Hα-helixtrans-63-43.4177.6-65.90000111.2W132 I138 I170 L171 H178W132-C174 HydrophobicContact CH2-CB 3.63Å; W132-C174 HydrophobicContact CZ3-CB 4.05Å; I138-C174 HydrophobicContact CD1-CB 3.52Å; I170-C174 WeakPolarHBondContact O-CB 3.35Å; I170-C174 PolarHBondContact O-N 3.38Å; I170-C174 PolarHBondContact O-SG 3.42Å; L171-C174 PolarHBondContact O-N 3Å; C174-H178 WeakPolarHBondContact O-CB 3.48Å; C174-H178 PolarHBondContact O-N 3.09Å
175M89.4Confident90.9Very high18 Ų1856.3 Ų56.39%0.08926%0.258CS..Hα-helixtrans-60.1-56.5175.7-77.2175.443.400112.2L171 L173 N177 H178 E179 Y377 V379 L381L171-M175 HydrophobicContact CD1-CG 4.24Å; L171-M175 HydrophobicContact CD1-SD 4.04Å; L171-M175 HydrophobicContact CG-SD 3.97Å; L171-M175 WeakPolarHBondContact O-CB 3.33Å; L171-M175 WeakPolarHBondContact O-CG 3.49Å; L171-M175 PolarHBondContact O-N 3.12Å; L173-M175 VanDerWaalsContact C-N 3.34Å; M175-N177 VanDerWaalsContact C-N 3.33Å; M175-N177 PolarHBondContact O-N 3.12Å; M175-H178 PolarHBondContact O-N 2.66Å; M175-E179 WeakPolarHBondContact O-CB 3.34Å; M175-E179 PolarHBondContact O-N 2.73Å; M175-Y377 HydrophobicContact CE-CD1 3.47Å; M175-Y377 VanDerWaalsContact CE-CD1 3.47Å; M175-Y377 HydrophobicContact CE-CD2 3.96Å; M175-Y377 HydrophobicContact CE-CE1 4.13Å; M175-Y377 HydrophobicContact CE-CG 3.37Å; M175-Y377 HydrophobicContact SD-CG 4.09Å; M175-V379 HydrophobicContact CE-CB 4.18Å; M175-V379 HydrophobicContact CE-CG2 3.39Å; M175-V379 HydrophobicContact CG-CB 4.26Å; M175-V379 HydrophobicContact CG-CG2 4.46Å; M175-V379 HydrophobicContact SD-CB 4.02Å; M175-V379 HydrophobicContact SD-CG2 3.74Å; M175-L381 HydrophobicContact CG-CD2 4.26Å
176G89.8Confident90.6Very high29 Ų2952.5 Ų52.530%0.29925%0.247SC..Hα-helixtrans-63.4-36.9-177.200000113.2A172 L180A172-G176 PolarHBondContact O-N 2.87Å; G176-L180 WeakPolarHBondContact O-CB 3.44Å; G176-L180 VanDerWaalsContact O-CG 3.26Å; G176-L180 WeakPolarHBondContact O-CG 3.45Å; G176-L180 PolarHBondContact O-N 2.84Å; G176-L180 VanDerWaalsContact O-N 3.11Å
177N93.7Very high90.4Very high27 Ų2756.6 Ų56.614%0.14428%0.275CS..Hα-helixtrans-69.4-41.2174.6-78.8-74.4000112.2D111 A112 W132 L173 M175 Y181D111-N177 WeakPolarHBondContact O-CB 3.49Å; A112-N177 WeakPolarHBondContact CA-OD1 3.23Å; A112-N177 PolarHBondContact N-OD1 3Å; W132-N177 HydrophobicContact CZ2-CB 3.81Å; L173-N177 VanDerWaalsContact O-CB 3.32Å; L173-N177 WeakPolarHBondContact O-CB 3.34Å; L173-N177 PolarHBondContact O-N 2.68Å; L173-N177 PolarHBondContact O-ND2 2.66Å; M175-N177 VanDerWaalsContact C-N 3.33Å; M175-N177 PolarHBondContact O-N 3.12Å; N177-Y181 WeakPolarHBondContact O-CB 3.25Å; N177-Y181 PolarHBondContact O-N 2.71Å
178H91.1Very high90.2Very high4 Ų459.6 Ų59.62%0.01929%0.292CS..Hα-helixtrans-64.1-46.5175.8-179.9-75.4000112.1W132 C174 M175 L180 Y181 M182 L381 T382W132-H178 HydrophobicContact CD2-CB 4.1Å; W132-H178 HydrophobicContact CE3-CB 3.95Å; W132-H178 HydrophobicContact CG-CB 4.48Å; W132-H178 HydrophobicContact CZ3-CB 4.48Å; C174-H178 WeakPolarHBondContact O-CB 3.48Å; C174-H178 PolarHBondContact O-N 3.09Å; M175-H178 PolarHBondContact O-N 2.66Å; H178-L180 PolarHBondContact O-N 3.24Å; H178-Y181 WeakPolarHBondContact O-CB 3.19Å; H178-Y181 PolarHBondContact O-N 2.87Å; H178-M182 VanDerWaalsContact CE1-CG 3.43Å; H178-M182 WeakPolarHBondContact CE1-CG 3.32Å; H178-M182 VanDerWaalsContact NE2-CE 3.31Å; H178-M182 WeakPolarHBondContact NE2-CE 3.43Å; H178-M182 WeakPolarHBondContact O-CG 3.35Å; H178-M182 PolarHBondContact O-N 3.42Å; H178-L381 HydrophobicContact CB-CD1 4.49Å; H178-L381 HydrophobicContact CB-CD2 4.08Å; H178-L381 PolarHBondContact CE1-O 2.96Å; H178-T382 WeakPolarHBondContact NE2-CG2 3.18Å
179E89Confident90.2Very high132 Ų13255.9 Ų55.962%0.61728%0.28SS*.Hα-helixtrans-57.8-49.9177.6-172.2-170.8153.900111M175 Y181 M182 R183M175-E179 WeakPolarHBondContact O-CB 3.34Å; M175-E179 PolarHBondContact O-N 2.73Å; E179-Y181 VanDerWaalsContact C-N 3.34Å; E179-Y181 PolarHBondContact O-N 3.02Å; E179-M182 PolarHBondContact O-N 3.05Å; E179-R183 PolarHBondContact O-N 2.72Å
180L90.5Very high90.1Very high78 Ų7855 Ų5541%0.40829%0.285SS..Hα-helixtrans-66.6-33.9176.5-66.6173.8000112.4G176 H178 M182 R183 R184G176-L180 WeakPolarHBondContact O-CB 3.44Å; G176-L180 VanDerWaalsContact O-CG 3.26Å; G176-L180 WeakPolarHBondContact O-CG 3.45Å; G176-L180 PolarHBondContact O-N 2.84Å; G176-L180 VanDerWaalsContact O-N 3.11Å; H178-L180 PolarHBondContact O-N 3.24Å; L180-M182 VanDerWaalsContact C-N 3.31Å; L180-M182 PolarHBondContact O-N 2.83Å; L180-R183 PolarHBondContact O-N 3.45Å; L180-R184 WeakPolarHBondContact O-CB 3.32Å; L180-R184 VanDerWaalsContact O-CD 3.3Å; L180-R184 WeakPolarHBondContact O-CD 3.31Å; L180-R184 WeakPolarHBondContact O-CG 3.25Å; L180-R184 PolarHBondContact O-N 2.72Å
181Y92.3Very high89.9Confident2 Ų260.9 Ų60.91%0.00831%0.313CS..Hα-helixtrans-62.4-37.8173.8176-86.3000112.1W132 S133 N177 H178 E179 R185 E393W132-Y181 HydrophobicContact CB-CD1 3.4Å; W132-Y181 VanDerWaalsContact CB-CD1 3.4Å; W132-Y181 HydrophobicContact CB-CD2 3.91Å; W132-Y181 HydrophobicContact CB-CE1 3.57Å; W132-Y181 HydrophobicContact CB-CE2 4.05Å; W132-Y181 HydrophobicContact CB-CG 3.57Å; W132-Y181 AromaticContact CD1-CD2 3.6Å; W132-Y181 AromaticContact CD1-CG 3.72Å; W132-Y181 HydrophobicContact CG-CD1 4.3Å; W132-Y181 HydrophobicContact CG-CD2 4.16Å; W132-Y181 AromaticContact CG-CG 3.99Å; W132-Y181 HydrophobicContact CG-CG 3.99Å; S133-Y181 PolarHBondContact OG-OH 3.03Å; N177-Y181 WeakPolarHBondContact O-CB 3.25Å; N177-Y181 PolarHBondContact O-N 2.71Å; H178-Y181 WeakPolarHBondContact O-CB 3.19Å; H178-Y181 PolarHBondContact O-N 2.87Å; E179-Y181 VanDerWaalsContact C-N 3.34Å; E179-Y181 PolarHBondContact O-N 3.02Å; Y181-R185 VanDerWaalsContact CE2-CZ 3.5Å; Y181-R185 VanDerWaalsContact CZ-NH2 3.34Å; Y181-R185 VanDerWaalsContact O-CD 3.29Å; Y181-R185 WeakPolarHBondContact O-CD 3.27Å; Y181-R185 WeakPolarHBondContact O-CG 3.34Å; Y181-R185 PolarHBondContact O-NH1 3.38Å; Y181-R185 PolarHBondContact OH-NH2 3.35Å; Y181-R185 VanDerWaalsContact OH-NH2 3.16Å; Y181-E393 VanDerWaalsContact CE2-OE1 3.23Å; Y181-E393 WeakPolarHBondContact CE2-OE1 3.48Å; Y181-E393 PolarHBondContact OH-OE1 3.23Å
182M88.3Confident89.7Confident6 Ų661.3 Ų61.33%0.0332%0.316CS..Hα-helixtrans-79.2-35.3175.1-66.2-55176.200112.8H178 E179 L180 R184 R185 K186 T382 Y386 V389H178-M182 VanDerWaalsContact CE1-CG 3.43Å; H178-M182 WeakPolarHBondContact CE1-CG 3.32Å; H178-M182 VanDerWaalsContact NE2-CE 3.31Å; H178-M182 WeakPolarHBondContact NE2-CE 3.43Å; H178-M182 WeakPolarHBondContact O-CG 3.35Å; H178-M182 PolarHBondContact O-N 3.42Å; E179-M182 PolarHBondContact O-N 3.05Å; L180-M182 VanDerWaalsContact C-N 3.31Å; L180-M182 PolarHBondContact O-N 2.83Å; M182-R184 VanDerWaalsContact C-N 3.32Å; M182-R184 PolarHBondContact O-N 3.31Å; M182-R185 WeakPolarHBondContact O-CB 3.31Å; M182-R185 PolarHBondContact O-N 2.95Å; M182-R185 VanDerWaalsContact O-N 3.09Å; M182-K186 PolarHBondContact O-N 3.21Å; M182-T382 HydrophobicContact CE-CG2 3.77Å; M182-Y386 HydrophobicContact CB-CD1 4.36Å; M182-Y386 HydrophobicContact CB-CE1 3.84Å; M182-Y386 HydrophobicContact CG-CD1 4.09Å; M182-Y386 HydrophobicContact CG-CE1 4.02Å; M182-Y386 HydrophobicContact SD-CD1 3.57Å; M182-Y386 VanDerWaalsContact SD-CD1 3.57Å; M182-Y386 HydrophobicContact SD-CE1 4.06Å; M182-Y386 HydrophobicContact SD-CG 4.14Å; M182-V389 HydrophobicContact SD-CG2 4.31Å
183R87.4Confident89.8Confident126 Ų12663.8 Ų63.848%0.47532%0.318SS..Hα-helixtrans-59.7-43172.3-172.8174.6179.7166.62.9111.1E179 L180 R185 K186 T189E179-R183 PolarHBondContact O-N 2.72Å; L180-R183 PolarHBondContact O-N 3.45Å; R183-R185 PolarHBondContact O-N 2.99Å; R183-K186 PolarHBondContact O-N 3.38Å; R183-T189 PolarHBondContact NH2-OG1 2.85Å
184R88.9Confident89.8Confident114 Ų11467.5 Ų67.543%0.4334%0.335SS..THydrogen-bonded Turntrans-63.6-0.7174.8-68.3163.9-166.7134.70115L180 M182L180-R184 WeakPolarHBondContact O-CB 3.32Å; L180-R184 VanDerWaalsContact O-CD 3.3Å; L180-R184 WeakPolarHBondContact O-CD 3.31Å; L180-R184 WeakPolarHBondContact O-CG 3.25Å; L180-R184 PolarHBondContact O-N 2.72Å; M182-R184 VanDerWaalsContact C-N 3.32Å; M182-R184 PolarHBondContact O-N 3.31Å
185R86.7Confident89.7Confident30 Ų3073.5 Ų73.511%0.11336%0.364CS..THydrogen-bonded Turntrans-115-12.5-179.1-73.2167.1156.465.216113.9Y181 M182 R183 V389 P390 E393Y181-R185 VanDerWaalsContact CE2-CZ 3.5Å; Y181-R185 VanDerWaalsContact CZ-NH2 3.34Å; Y181-R185 VanDerWaalsContact O-CD 3.29Å; Y181-R185 WeakPolarHBondContact O-CD 3.27Å; Y181-R185 WeakPolarHBondContact O-CG 3.34Å; Y181-R185 PolarHBondContact O-NH1 3.38Å; Y181-R185 PolarHBondContact OH-NH2 3.35Å; Y181-R185 VanDerWaalsContact OH-NH2 3.16Å; M182-R185 WeakPolarHBondContact O-CB 3.31Å; M182-R185 PolarHBondContact O-N 2.95Å; M182-R185 VanDerWaalsContact O-N 3.09Å; R183-R185 PolarHBondContact O-N 2.99Å; R185-V389 HydrophobicContact CB-CB 4.28Å; R185-V389 HydrophobicContact CB-CG1 3.92Å; R185-V389 HydrophobicContact CG-CB 4.39Å; R185-P390 VanDerWaalsContact CZ-O 3.24Å; R185-P390 PolarHBondContact NE-O 3.15Å; R185-P390 PolarHBondContact NH2-O 3.41Å; R185-E393 IonicContact CZ-OE2 3.62Å; R185-E393 VanDerWaalsContact NH2-CD 3.28Å; R185-E393 IonicContact NH2-OE1 3.46Å; R185-E393 PolarHBondContact NH2-OE1 2.88Å; R185-E393 VanDerWaalsContact NH2-OE1 3.08Å; R185-E393 IonicContact NH2-OE2 3.61Å; R185-E393 PolarHBondContact NH2-OE2 3.27Å
186K85.2Confident89.9Confident101 Ų10178.8 Ų78.844%0.43938%0.383SS..SBendtrans-90.5158.4168.3-57.2-166.2-177.7-164.50108.2M182 R183 E385 Y386M182-K186 PolarHBondContact O-N 3.21Å; R183-K186 PolarHBondContact O-N 3.38Å; K186-E385 IonicContact NZ-OE2 2.64Å; K186-Y386 WeakPolarHBondContact CE-OH 3.49Å; K186-Y386 PolarHBondContact NZ-OH 3.31Å
187P86.3Confident90.1Very high119 Ų11979.7 Ų79.777%0.77339%0.388SS*.PPolyproline II helixtrans-53.5148166.8-24.334.9000111
188D86.5Confident90.1Very high64 Ų6482.5 Ų82.534%0.34240%0.4SS..PPolyproline II helixtrans-57.1139.9177.2-76.5-38.3000111.1V192 Q193 R196D188-V192 HydrophobicContact CB-CB 4.09Å; D188-V192 HydrophobicContact CB-CG1 3.82Å; D188-V192 WeakPolarHBondContact OD1-CG1 3.46Å; D188-Q193 HydrophobicContact CB-CG 3.81Å; D188-Q193 PolarHBondContact O-NE2 2.88Å; D188-R196 IonicContact OD1-CZ 3.86Å; D188-R196 IonicContact OD1-NE 2.69Å; D188-R196 IonicContact OD1-NH2 2.83Å; D188-R196 PolarHBondContact OD1-NH2 3.17Å; D188-R196 VanDerWaalsContact OD1-NH2 3.14Å; D188-R196 IonicContact OD2-CZ 2.81Å; D188-R196 IonicContact OD2-NE 3.75Å; D188-R196 PolarHBondContact OD2-NE 3.1Å; D188-R196 IonicContact OD2-NH2 3.89Å; D188-R196 PolarHBondContact OD2-NH2 2.67Å
189T89.2Confident90.2Very high58 Ų5885.1 Ų85.136%0.35642%0.422SS..PPolyproline II helixtrans-64.4156.717457.30000110.7R183 E191 V192 Q193R183-T189 PolarHBondContact NH2-OG1 2.85Å; T189-E191 PolarHBondContact O-N 3.4Å; T189-E191 PolarHBondContact OG1-OE2 3.24Å; T189-V192 WeakPolarHBondContact O-CA 3.35Å; T189-V192 PolarHBondContact O-N 2.91Å; T189-V192 WeakPolarHBondContact OG1-CG2 3.39Å; T189-Q193 WeakPolarHBondContact O-CG 3.43Å; T189-Q193 PolarHBondContact O-N 2.81Å
190I90.8Very high90.3Very high127 Ų12786 Ų8665%0.65142%0.42SS*.Hα-helixtrans-52.2-44.5-178.9-62.7172.6000110.7V192 Q193 Q194I190-V192 PolarHBondContact O-N 2.82Å; I190-Q193 WeakPolarHBondContact O-CB 3.36Å; I190-Q193 PolarHBondContact O-N 2.73Å; I190-Q193 VanDerWaalsContact O-N 3.16Å; I190-Q194 HydrophobicContact CG2-CG 4.47Å; I190-Q194 WeakPolarHBondContact O-CG 3.5Å; I190-Q194 PolarHBondContact O-N 3.11Å
191E90.5Very high90.5Very high123 Ų12388 Ų8858%0.57543%0.427SS*.Hα-helixtrans-53.5-49.1173.3-53.3156.7153.400112.1T189 Q193 Q194 M195T189-E191 PolarHBondContact O-N 3.4Å; T189-E191 PolarHBondContact OG1-OE2 3.24Å; E191-Q193 VanDerWaalsContact C-N 3.33Å; E191-Q193 PolarHBondContact O-N 3.27Å; E191-Q194 PolarHBondContact O-N 2.88Å; E191-M195 WeakPolarHBondContact O-CB 3.39Å; E191-M195 VanDerWaalsContact O-CG 3.27Å; E191-M195 WeakPolarHBondContact O-CG 3.39Å; E191-M195 PolarHBondContact O-N 3.3Å
192V88.7Confident90.5Very high31 Ų3191.6 Ų91.619%0.18844%0.444CS..Hα-helixtrans-68.6-34.3-179.7173.50000110.9D188 T189 I190 R196D188-V192 HydrophobicContact CB-CB 4.09Å; D188-V192 HydrophobicContact CB-CG1 3.82Å; D188-V192 WeakPolarHBondContact OD1-CG1 3.46Å; T189-V192 WeakPolarHBondContact O-CA 3.35Å; T189-V192 PolarHBondContact O-N 2.91Å; T189-V192 WeakPolarHBondContact OG1-CG2 3.39Å; I190-V192 PolarHBondContact O-N 2.82Å; V192-R196 HydrophobicContact CG1-CG 4.44Å; V192-R196 VanDerWaalsContact O-CB 3.28Å; V192-R196 WeakPolarHBondContact O-CB 3.29Å; V192-R196 VanDerWaalsContact O-CG 3.22Å; V192-R196 WeakPolarHBondContact O-CG 3.23Å; V192-R196 PolarHBondContact O-N 3.12Å
193Q92.2Very high90.5Very high106 Ų10696.5 Ų96.550%0.49546%0.462SS..Hα-helixtrans-65.7-41.4173.4-63.9-177.236.500111.6D188 T189 I190 E191 R196 A197D188-Q193 HydrophobicContact CB-CG 3.81Å; D188-Q193 PolarHBondContact O-NE2 2.88Å; T189-Q193 WeakPolarHBondContact O-CG 3.43Å; T189-Q193 PolarHBondContact O-N 2.81Å; I190-Q193 WeakPolarHBondContact O-CB 3.36Å; I190-Q193 PolarHBondContact O-N 2.73Å; I190-Q193 VanDerWaalsContact O-N 3.16Å; E191-Q193 VanDerWaalsContact C-N 3.33Å; E191-Q193 PolarHBondContact O-N 3.27Å; Q193-R196 PolarHBondContact O-N 2.98Å; Q193-A197 PolarHBondContact O-N 3.08Å
194Q93.9Very high90.7Very high123 Ų12397.1 Ų97.158%0.57547%0.47SS*.Hα-helixtrans-65.3-50.4174.8-72.5170.4-43.900111.7I190 E191 R196 A197 Q198I190-Q194 HydrophobicContact CG2-CG 4.47Å; I190-Q194 WeakPolarHBondContact O-CG 3.5Å; I190-Q194 PolarHBondContact O-N 3.11Å; E191-Q194 PolarHBondContact O-N 2.88Å; Q194-R196 VanDerWaalsContact C-N 3.27Å; Q194-R196 PolarHBondContact O-N 2.85Å; Q194-A197 WeakPolarHBondContact O-CA 3.37Å; Q194-A197 WeakPolarHBondContact O-CB 3.21Å; Q194-A197 PolarHBondContact O-N 3.16Å; Q194-Q198 PolarHBondContact O-N 3.3Å
195M93.6Very high90.9Very high126 Ų12696.5 Ų96.562%0.62147%0.473SS*.Hα-helixtrans-57-39.5174.5-69.2177.380.500111.9E191 A197 A199E191-M195 WeakPolarHBondContact O-CB 3.39Å; E191-M195 VanDerWaalsContact O-CG 3.27Å; E191-M195 WeakPolarHBondContact O-CG 3.39Å; E191-M195 PolarHBondContact O-N 3.3Å; M195-A197 VanDerWaalsContact C-N 3.3Å; M195-A197 PolarHBondContact O-N 3.49Å; M195-A199 WeakPolarHBondContact O-CB 3.22Å; M195-A199 PolarHBondContact O-N 2.91Å
196R92.8Very high90.9Very high129 Ų129100 Ų10049%0.48749%0.488SS..Hα-helixtrans-69.8-22.9173.2-76.2-173.7-160.1-95.916.5113.3D188 V192 Q193 Q194 R200D188-R196 IonicContact OD1-CZ 3.86Å; D188-R196 IonicContact OD1-NE 2.69Å; D188-R196 IonicContact OD1-NH2 2.83Å; D188-R196 PolarHBondContact OD1-NH2 3.17Å; D188-R196 VanDerWaalsContact OD1-NH2 3.14Å; D188-R196 IonicContact OD2-CZ 2.81Å; D188-R196 IonicContact OD2-NE 3.75Å; D188-R196 PolarHBondContact OD2-NE 3.1Å; D188-R196 IonicContact OD2-NH2 3.89Å; D188-R196 PolarHBondContact OD2-NH2 2.67Å; V192-R196 HydrophobicContact CG1-CG 4.44Å; V192-R196 VanDerWaalsContact O-CB 3.28Å; V192-R196 WeakPolarHBondContact O-CB 3.29Å; V192-R196 VanDerWaalsContact O-CG 3.22Å; V192-R196 WeakPolarHBondContact O-CG 3.23Å; V192-R196 PolarHBondContact O-N 3.12Å; Q193-R196 PolarHBondContact O-N 2.98Å; Q194-R196 VanDerWaalsContact C-N 3.27Å; Q194-R196 PolarHBondContact O-N 2.85Å; R196-R200 WeakPolarHBondContact O-CG 3.42Å; R196-R200 PolarHBondContact O-NE 2.93Å; R196-R200 PolarHBondContact O-NH2 3.31Å
197A94.4Very high91.1Very high48 Ų4897.4 Ų97.440%0.39748%0.481SS..Hα-helixtrans-77.2-54.7174.300000109.6Q193 Q194 M195 A199 R200 E201Q193-A197 PolarHBondContact O-N 3.08Å; Q194-A197 WeakPolarHBondContact O-CA 3.37Å; Q194-A197 WeakPolarHBondContact O-CB 3.21Å; Q194-A197 PolarHBondContact O-N 3.16Å; M195-A197 VanDerWaalsContact C-N 3.3Å; M195-A197 PolarHBondContact O-N 3.49Å; A197-A199 PolarHBondContact O-N 3.14Å; A197-R200 WeakPolarHBondContact O-CA 3.5Å; A197-R200 WeakPolarHBondContact O-CB 3.36Å; A197-R200 PolarHBondContact O-N 3.08Å; A197-E201 PolarHBondContact O-N 2.94Å
198Q94.4Very high91.3Very high85 Ų8594.3 Ų94.340%0.39747%0.465SS..Hα-helixtrans-52-51.7175-177.4168.824.400112.1Q194 R200 E201 E202 E367Q194-Q198 PolarHBondContact O-N 3.3Å; Q198-R200 PolarHBondContact O-N 2.87Å; Q198-R200 VanDerWaalsContact O-N 3.13Å; Q198-E201 PolarHBondContact O-N 2.89Å; Q198-E202 PolarHBondContact O-N 3.12Å; Q198-E367 PolarHBondContact NE2-OE2 3.41Å
199A91.8Very high91.3Very high59 Ų5997.8 Ų97.849%0.48848%0.479SS..Hα-helixtrans-67.4-13.8178.200000114.5M195 A197 R203M195-A199 WeakPolarHBondContact O-CB 3.22Å; M195-A199 PolarHBondContact O-N 2.91Å; A197-A199 PolarHBondContact O-N 3.14Å; A199-R203 WeakPolarHBondContact O-CB 3.38Å
200R92.5Very high91.1Very high152 Ų15298.1 Ų98.157%0.57447%0.474SS*.Hα-helixtrans-87-38168.7-85.8-179.8-74.4-173.6-0.4111.4R196 A197 Q198 R203 Q204R196-R200 WeakPolarHBondContact O-CG 3.42Å; R196-R200 PolarHBondContact O-NE 2.93Å; R196-R200 PolarHBondContact O-NH2 3.31Å; A197-R200 WeakPolarHBondContact O-CA 3.5Å; A197-R200 WeakPolarHBondContact O-CB 3.36Å; A197-R200 PolarHBondContact O-N 3.08Å; Q198-R200 PolarHBondContact O-N 2.87Å; Q198-R200 VanDerWaalsContact O-N 3.13Å; R200-R203 PolarHBondContact O-N 2.87Å; R200-Q204 WeakPolarHBondContact O-CG 3.37Å; R200-Q204 PolarHBondContact O-N 2.74Å
201E93.3Very high90.9Very high118 Ų11895.9 Ų95.955%0.55146%0.461SS*.Hα-helixtrans-67.7-51176.9-175.3166.4-174.100111.8A197 Q198 R203 Q204 Q205A197-E201 PolarHBondContact O-N 2.94Å; Q198-E201 PolarHBondContact O-N 2.89Å; E201-R203 PolarHBondContact O-N 3.21Å; E201-Q204 WeakPolarHBondContact O-CA 3.08Å; E201-Q204 WeakPolarHBondContact O-CB 3.26Å; E201-Q204 PolarHBondContact O-N 3.14Å; E201-Q205 WeakPolarHBondContact O-CG 3.43Å; E201-Q205 PolarHBondContact O-N 2.82Å
202E92.1Very high90.8Very high79 Ų7996.9 Ų96.937%0.36946%0.46SS..Hα-helixtrans-53.5-39.5172.1-74.2-178.4-142.600112.2Q198 K206Q198-E202 PolarHBondContact O-N 3.12Å; E202-K206 WeakPolarHBondContact O-CB 3.44Å; E202-K206 VanDerWaalsContact O-CG 3.29Å; E202-K206 WeakPolarHBondContact O-CG 3.33Å; E202-K206 PolarHBondContact O-N 2.72Å; E202-K206 IonicContact OE2-NZ 3.59Å; E202-K206 PolarHBondContact OE2-NZ 3.43Å
203R89.6Confident90.6Very high108 Ų108100.1 Ų100.141%0.40848%0.475SS..Hα-helixtrans-69.5-38.7178-179.1175169.2126.28111.2D76 A199 R200 E201 V207D76-R203 IonicContact OD1-CZ 3.39Å; D76-R203 VanDerWaalsContact OD1-CZ 3.23Å; D76-R203 IonicContact OD1-NH1 3.73Å; D76-R203 PolarHBondContact OD1-NH1 3.48Å; D76-R203 IonicContact OD1-NH2 2.74Å; D76-R203 PolarHBondContact OD1-NH2 2.9Å; D76-R203 IonicContact OD2-CZ 3.66Å; D76-R203 IonicContact OD2-NH1 3.49Å; D76-R203 IonicContact OD2-NH2 2.91Å; D76-R203 PolarHBondContact OD2-NH2 3.27Å; A199-R203 WeakPolarHBondContact O-CB 3.38Å; R200-R203 PolarHBondContact O-N 2.87Å; E201-R203 PolarHBondContact O-N 3.21Å; R203-V207 VanDerWaalsContact O-CG2 3.24Å; R203-V207 WeakPolarHBondContact O-CG2 3.34Å; R203-V207 PolarHBondContact O-N 2.97Å
204Q91.5Very high90.2Very high139 Ų13999.1 Ų99.165%0.6547%0.471SS*.Hα-helixtrans-66-41.2174.2-76.8173.6-13.200111.6R200 E201 V207 A208R200-Q204 WeakPolarHBondContact O-CG 3.37Å; R200-Q204 PolarHBondContact O-N 2.74Å; E201-Q204 WeakPolarHBondContact O-CA 3.08Å; E201-Q204 WeakPolarHBondContact O-CB 3.26Å; E201-Q204 PolarHBondContact O-N 3.14Å; Q204-V207 PolarHBondContact O-N 2.65Å; Q204-A208 WeakPolarHBondContact O-CB 3.43Å; Q204-A208 PolarHBondContact O-N 3.33Å
205Q92.1Very high89.6Confident102 Ų102100.5 Ų100.548%0.47747%0.47SS..Hα-helixtrans-58.7-52.1173.3-68.8167.7-2.200111E201 V207 A208 E209E201-Q205 WeakPolarHBondContact O-CG 3.43Å; E201-Q205 PolarHBondContact O-N 2.82Å; Q205-V207 VanDerWaalsContact C-N 3.31Å; Q205-V207 PolarHBondContact O-N 2.72Å; Q205-A208 PolarHBondContact O-N 3.19Å; Q205-A208 VanDerWaalsContact O-N 3.13Å; Q205-E209 WeakPolarHBondContact O-CB 3.49Å; Q205-E209 PolarHBondContact O-N 3.44Å
206K88.2Confident89Confident102 Ų102100.1 Ų100.144%0.44347%0.467SS..Hα-helixtrans-61.2-33.9177.2-71.6166.8-174.71640113.5E202 R210E202-K206 WeakPolarHBondContact O-CB 3.44Å; E202-K206 VanDerWaalsContact O-CG 3.29Å; E202-K206 WeakPolarHBondContact O-CG 3.33Å; E202-K206 PolarHBondContact O-N 2.72Å; E202-K206 IonicContact OE2-NZ 3.59Å; E202-K206 PolarHBondContact OE2-NZ 3.43Å; K206-R210 VanDerWaalsContact O-CB 3.32Å; K206-R210 WeakPolarHBondContact O-CB 3.23Å; K206-R210 PolarHBondContact O-N 2.78Å; K206-R210 VanDerWaalsContact O-N 3.08Å
207V87.9Confident88.5Confident48 Ų4897.9 Ų97.929%0.29146%0.464SS..Hα-helixtrans-66.5-50.4171.6169.50000110.5M73 R203 Q204 Q205 E209 R210 E211M73-V207 HydrophobicContact CE-CB 4.22Å; M73-V207 HydrophobicContact CE-CG2 3.51Å; M73-V207 HydrophobicContact SD-CG2 4.02Å; R203-V207 VanDerWaalsContact O-CG2 3.24Å; R203-V207 WeakPolarHBondContact O-CG2 3.34Å; R203-V207 PolarHBondContact O-N 2.97Å; Q204-V207 PolarHBondContact O-N 2.65Å; Q205-V207 VanDerWaalsContact C-N 3.31Å; Q205-V207 PolarHBondContact O-N 2.72Å; V207-E209 PolarHBondContact O-N 2.69Å; V207-R210 PolarHBondContact O-N 2.87Å; V207-E211 HydrophobicContact CG1-CG 4.37Å; V207-E211 WeakPolarHBondContact O-CB 3.31Å; V207-E211 WeakPolarHBondContact O-CG 3.36Å; V207-E211 PolarHBondContact O-N 2.78Å
208A90.4Very high88Confident53 Ų5398.2 Ų98.244%0.43847%0.467SS..Hα-helixtrans-63-39.2-179.200000112.7Q204 Q205 R212Q204-A208 WeakPolarHBondContact O-CB 3.43Å; Q204-A208 PolarHBondContact O-N 3.33Å; Q205-A208 PolarHBondContact O-N 3.19Å; Q205-A208 VanDerWaalsContact O-N 3.13Å; A208-R212 WeakPolarHBondContact O-CB 3.46Å; A208-R212 PolarHBondContact O-N 2.81Å
209E88.1Confident87.4Confident137 Ų13797 Ų9764%0.6447%0.472SS*.Hα-helixtrans-62.6-50.5173.4-171.8-167.6-176.600111.2Q205 V207 E211 R212 L213Q205-E209 WeakPolarHBondContact O-CB 3.49Å; Q205-E209 PolarHBondContact O-N 3.44Å; V207-E209 PolarHBondContact O-N 2.69Å; E209-E211 VanDerWaalsContact C-N 3.34Å; E209-E211 PolarHBondContact O-N 3.41Å; E209-R212 WeakPolarHBondContact O-CB 3.35Å; E209-R212 PolarHBondContact O-N 3.09Å; E209-R212 VanDerWaalsContact O-N 3.16Å; E209-L213 PolarHBondContact O-N 2.79Å
210R83.9Confident86.8Confident66 Ų66102.2 Ų102.225%0.24948%0.478CS..Hα-helixtrans-62.8-40.3178.5-172179.8-178.8-152.52.9111.9D26 C71 M73 K206 V207 L213 Q214D26-R210 IonicContact OD1-NH2 2.89Å; C71-R210 PolarHBondContact O-NH1 2.68Å; C71-R210 PolarHBondContact O-NH2 3.47Å; M73-R210 HydrophobicContact CE-CB 4.36Å; K206-R210 VanDerWaalsContact O-CB 3.32Å; K206-R210 WeakPolarHBondContact O-CB 3.23Å; K206-R210 PolarHBondContact O-N 2.78Å; K206-R210 VanDerWaalsContact O-N 3.08Å; V207-R210 PolarHBondContact O-N 2.87Å; R210-L213 PolarHBondContact O-N 3.27Å; R210-Q214 WeakPolarHBondContact O-CB 3.26Å; R210-Q214 WeakPolarHBondContact O-CG 3.42Å; R210-Q214 PolarHBondContact O-N 3.2Å
211E87.3Confident86.3Confident80 Ų8099.3 Ų99.337%0.37447%0.472SS..Hα-helixtrans-65.3-39.5174-72.8-172.3177.100112.1V207 E209 Q214 R215V207-E211 HydrophobicContact CG1-CG 4.37Å; V207-E211 WeakPolarHBondContact O-CB 3.31Å; V207-E211 WeakPolarHBondContact O-CG 3.36Å; V207-E211 PolarHBondContact O-N 2.78Å; E209-E211 VanDerWaalsContact C-N 3.34Å; E209-E211 PolarHBondContact O-N 3.41Å; E211-Q214 PolarHBondContact O-N 2.96Å; E211-R215 VanDerWaalsContact CB-NH1 3.3Å; E211-R215 WeakPolarHBondContact O-CB 3.33Å; E211-R215 WeakPolarHBondContact O-CG 3.37Å; E211-R215 PolarHBondContact O-N 3.14Å; E211-R215 IonicContact OE2-CZ 3.13Å; E211-R215 VanDerWaalsContact OE2-CZ 3.24Å; E211-R215 IonicContact OE2-NH1 2.73Å; E211-R215 PolarHBondContact OE2-NH1 3.32Å; E211-R215 IonicContact OE2-NH2 2.7Å; E211-R215 PolarHBondContact OE2-NH2 3Å
212R88.5Confident85.7Confident144 Ų14496 Ų9654%0.54346%0.464SS..Hα-helixtrans-60.3-49174.2175.6-178.1170.3-179.3-2.6110.4A208 E209 Q214 R215 E216A208-R212 WeakPolarHBondContact O-CB 3.46Å; A208-R212 PolarHBondContact O-N 2.81Å; E209-R212 WeakPolarHBondContact O-CB 3.35Å; E209-R212 PolarHBondContact O-N 3.09Å; E209-R212 VanDerWaalsContact O-N 3.16Å; R212-Q214 PolarHBondContact O-N 3.49Å; R212-R215 PolarHBondContact O-N 3Å; R212-E216 WeakPolarHBondContact O-CB 3.49Å; R212-E216 PolarHBondContact O-N 2.95Å
213L84.4Confident85.2Confident98 Ų9895 Ų9551%0.51347%0.469SS..Hα-helixtrans-61.8-42.3177.7-178.661.1000111.9E209 R210 E216 I217E209-L213 PolarHBondContact O-N 2.79Å; R210-L213 PolarHBondContact O-N 3.27Å; L213-E216 PolarHBondContact O-N 3.04Å; L213-I217 HydrophobicContact CD1-CD1 4.12Å; L213-I217 HydrophobicContact CD1-CG1 4.36Å; L213-I217 HydrophobicContact CG-CD1 3.96Å; L213-I217 VanDerWaalsContact O-CG1 3.3Å; L213-I217 WeakPolarHBondContact O-CG1 3.41Å; L213-I217 PolarHBondContact O-N 3.39Å
214Q82.8Confident84.8Confident85 Ų8594.2 Ų94.240%0.39747%0.47SS..Hα-helixtrans-65.5-38.7175.4-77.3-176.3-3400112.6R210 E211 R212 E216 A218R210-Q214 WeakPolarHBondContact O-CB 3.26Å; R210-Q214 WeakPolarHBondContact O-CG 3.42Å; R210-Q214 PolarHBondContact O-N 3.2Å; E211-Q214 PolarHBondContact O-N 2.96Å; R212-Q214 PolarHBondContact O-N 3.49Å; Q214-E216 VanDerWaalsContact C-N 3.33Å; Q214-A218 VanDerWaalsContact O-CB 3.25Å; Q214-A218 WeakPolarHBondContact O-CB 3.4Å; Q214-A218 PolarHBondContact O-N 3.4Å
215R82.9Confident84.4Confident152 Ų15295.7 Ų95.757%0.57447%0.47SS*.Hα-helixtrans-63.7-38.9172.1-73.1169.5-173.7119.38.5111.6E211 R212 A219E211-R215 VanDerWaalsContact CB-NH1 3.3Å; E211-R215 WeakPolarHBondContact O-CB 3.33Å; E211-R215 WeakPolarHBondContact O-CG 3.37Å; E211-R215 PolarHBondContact O-N 3.14Å; E211-R215 IonicContact OE2-CZ 3.13Å; E211-R215 VanDerWaalsContact OE2-CZ 3.24Å; E211-R215 IonicContact OE2-NH1 2.73Å; E211-R215 PolarHBondContact OE2-NH1 3.32Å; E211-R215 IonicContact OE2-NH2 2.7Å; E211-R215 PolarHBondContact OE2-NH2 3Å; R212-R215 PolarHBondContact O-N 3Å; R215-A219 WeakPolarHBondContact O-CB 3.32Å; R215-A219 PolarHBondContact O-N 3.11Å
216E80.7Confident83.9Confident118 Ų11896.7 Ų96.755%0.55147%0.473SS*.Hα-helixtrans-69.1-44.5179.2-166.7168.7152.400111.9R212 L213 Q214 A219 R220R212-E216 WeakPolarHBondContact O-CB 3.49Å; R212-E216 PolarHBondContact O-N 2.95Å; L213-E216 PolarHBondContact O-N 3.04Å; Q214-E216 VanDerWaalsContact C-N 3.33Å; E216-A219 PolarHBondContact O-N 3.47Å; E216-R220 WeakPolarHBondContact O-CB 3.31Å; E216-R220 PolarHBondContact O-N 2.83Å
217I80.6Confident83.4Confident83 Ų8397.1 Ų97.143%0.42648%0.476SS..Hα-helixtrans-60.9-49.4172.7-67.3165.4000110.6L213 A219 R220 E221L213-I217 HydrophobicContact CD1-CD1 4.12Å; L213-I217 HydrophobicContact CD1-CG1 4.36Å; L213-I217 HydrophobicContact CG-CD1 3.96Å; L213-I217 VanDerWaalsContact O-CG1 3.3Å; L213-I217 WeakPolarHBondContact O-CG1 3.41Å; L213-I217 PolarHBondContact O-N 3.39Å; I217-A219 VanDerWaalsContact C-N 3.34Å; I217-A219 PolarHBondContact O-N 3.24Å; I217-R220 WeakPolarHBondContact O-CB 3.21Å; I217-R220 PolarHBondContact O-N 2.93Å; I217-R220 VanDerWaalsContact O-N 3.15Å; I217-E221 PolarHBondContact O-N 3.45Å
218A84Confident83.2Confident54 Ų54100.9 Ų100.945%0.44649%0.489SS..Hα-helixtrans-64.6-36.2179.300000112.8Q214 A222Q214-A218 VanDerWaalsContact O-CB 3.25Å; Q214-A218 WeakPolarHBondContact O-CB 3.4Å; Q214-A218 PolarHBondContact O-N 3.4Å; A218-A222 VanDerWaalsContact O-CB 3.25Å; A218-A222 WeakPolarHBondContact O-CB 3.43Å; A218-A222 PolarHBondContact O-N 3.01Å
219A82.6Confident82.8Confident61 Ų61102.8 Ų102.850%0.50449%0.489SS..Hα-helixtrans-67.3-37.7173.500000111.8R215 E216 I217 A223R215-A219 WeakPolarHBondContact O-CB 3.32Å; R215-A219 PolarHBondContact O-N 3.11Å; E216-A219 PolarHBondContact O-N 3.47Å; I217-A219 VanDerWaalsContact C-N 3.34Å; I217-A219 PolarHBondContact O-N 3.24Å; A219-A223 WeakPolarHBondContact O-CB 3.13Å; A219-A223 PolarHBondContact O-N 3.45Å
220R78.4Confident82.4Confident167 Ų167103.4 Ų103.463%0.6349%0.486SS*.Hα-helixtrans-66.3-49.9174.4179.8177.5171.1160.53.9111.8E216 I217 A222 A223 E224E216-R220 WeakPolarHBondContact O-CB 3.31Å; E216-R220 PolarHBondContact O-N 2.83Å; I217-R220 WeakPolarHBondContact O-CB 3.21Å; I217-R220 PolarHBondContact O-N 2.93Å; I217-R220 VanDerWaalsContact O-N 3.15Å; R220-A222 VanDerWaalsContact C-N 3.27Å; R220-A222 PolarHBondContact O-N 3.4Å; R220-A223 WeakPolarHBondContact O-CB 3.42Å; R220-A223 PolarHBondContact O-N 2.92Å; R220-E224 HydrophobicContact CG-CG 4.41Å; R220-E224 IonicContact CZ-OE1 3.4Å; R220-E224 VanDerWaalsContact CZ-OE1 3.25Å; R220-E224 IonicContact NE-OE1 2.74Å; R220-E224 PolarHBondContact NE-OE1 3.02Å; R220-E224 IonicContact NH2-OE1 3.39Å; R220-E224 PolarHBondContact NH2-OE1 3.23Å; R220-E224 WeakPolarHBondContact O-CG 3.12Å; R220-E224 PolarHBondContact O-N 2.66Å
221E82.4Confident82.3Confident92 Ų92104.9 Ų104.943%0.4350%0.496SS..Hα-helixtrans-57.5-40.5174.7-74.7-176.5-148.700111.7I217 R225I217-E221 PolarHBondContact O-N 3.45Å; E221-R225 WeakPolarHBondContact O-CB 3.3Å; E221-R225 VanDerWaalsContact O-CG 3.23Å; E221-R225 WeakPolarHBondContact O-CG 3.23Å; E221-R225 PolarHBondContact O-N 3.2Å; E221-R225 IonicContact OE2-NH2 3.08Å
222A80.9Confident82.2Confident48 Ų48105.5 Ų105.540%0.39750%0.502SS..Hα-helixtrans-68.7-32.8176.100000112.8A218 R220 K226A218-A222 VanDerWaalsContact O-CB 3.25Å; A218-A222 WeakPolarHBondContact O-CB 3.43Å; A218-A222 PolarHBondContact O-N 3.01Å; R220-A222 VanDerWaalsContact C-N 3.27Å; R220-A222 PolarHBondContact O-N 3.4Å; A222-K226 WeakPolarHBondContact O-CB 3.29Å; A222-K226 WeakPolarHBondContact O-CG 3.43Å; A222-K226 PolarHBondContact O-N 3.45Å; A222-K226 VanDerWaalsContact O-N 3.09Å
223A81.9Confident81.9Confident57 Ų57105.9 Ų105.947%0.47150%0.503SS..Hα-helixtrans-71.3-44.9173.900000111.7A219 R220 R225 K226 Q227A219-A223 WeakPolarHBondContact O-CB 3.13Å; A219-A223 PolarHBondContact O-N 3.45Å; R220-A223 WeakPolarHBondContact O-CB 3.42Å; R220-A223 PolarHBondContact O-N 2.92Å; A223-R225 PolarHBondContact O-N 2.88Å; A223-K226 PolarHBondContact O-N 3.46Å; A223-Q227 WeakPolarHBondContact O-CB 3.3Å; A223-Q227 PolarHBondContact O-N 3.13Å
224E81Confident81.7Confident93 Ų93105.1 Ų105.144%0.43550%0.499SS..Hα-helixtrans-63.3-39.4176.6-71.1174.9176.300111.3R220 Q227 K228R220-E224 HydrophobicContact CG-CG 4.41Å; R220-E224 IonicContact CZ-OE1 3.4Å; R220-E224 VanDerWaalsContact CZ-OE1 3.25Å; R220-E224 IonicContact NE-OE1 2.74Å; R220-E224 PolarHBondContact NE-OE1 3.02Å; R220-E224 IonicContact NH2-OE1 3.39Å; R220-E224 PolarHBondContact NH2-OE1 3.23Å; R220-E224 WeakPolarHBondContact O-CG 3.12Å; R220-E224 PolarHBondContact O-N 2.66Å; E224-Q227 PolarHBondContact O-N 2.89Å; E224-K228 PolarHBondContact O-N 3Å
225R83.5Confident81.9Confident169 Ų169106.9 Ų106.964%0.63851%0.509SS*.Hα-helixtrans-61.6-47.4170.6-73.4174.3-162.3-141.28.1112.4E221 A223 K228 E229E221-R225 WeakPolarHBondContact O-CB 3.3Å; E221-R225 VanDerWaalsContact O-CG 3.23Å; E221-R225 WeakPolarHBondContact O-CG 3.23Å; E221-R225 PolarHBondContact O-N 3.2Å; E221-R225 IonicContact OE2-NH2 3.08Å; A223-R225 PolarHBondContact O-N 2.88Å; R225-K228 PolarHBondContact O-N 3.14Å; R225-E229 PolarHBondContact O-N 2.93Å
226K80.6Confident81.8Confident123 Ų123103.3 Ų103.354%0.53550%0.499SS..Hα-helixtrans-65.3-39178-78.8-178.2176.4-1730112.7A222 A223 K228 E229 Y230A222-K226 WeakPolarHBondContact O-CB 3.29Å; A222-K226 WeakPolarHBondContact O-CG 3.43Å; A222-K226 PolarHBondContact O-N 3.45Å; A222-K226 VanDerWaalsContact O-N 3.09Å; A223-K226 PolarHBondContact O-N 3.46Å; K226-K228 VanDerWaalsContact C-N 3.32Å; K226-K228 PolarHBondContact O-N 2.79Å; K226-E229 PolarHBondContact O-N 3.05Å; K226-Y230 HydrophobicContact CB-CE2 4.32Å; K226-Y230 WeakPolarHBondContact O-CD2 3.36Å; K226-Y230 PolarHBondContact O-N 3.02Å
227Q78.2Confident81.8Confident111 Ų111101.2 Ų101.252%0.51949%0.49SS..Hα-helixtrans-58.2-48173178177.4-22.500109.9A223 E224 E229 Y230 E231A223-Q227 WeakPolarHBondContact O-CB 3.3Å; A223-Q227 PolarHBondContact O-N 3.13Å; E224-Q227 PolarHBondContact O-N 2.89Å; Q227-E229 PolarHBondContact O-N 3.19Å; Q227-Y230 PolarHBondContact O-N 3.43Å; Q227-Y230 VanDerWaalsContact O-N 3.11Å; Q227-E231 HydrophobicContact CG-CG 4.44Å; Q227-E231 WeakPolarHBondContact CG-OE1 3.13Å; Q227-E231 PolarHBondContact NE2-OE1 2.76Å; Q227-E231 WeakPolarHBondContact O-CG 3.34Å; Q227-E231 PolarHBondContact O-N 2.76Å
228K84.8Confident81.8Confident128 Ų128102.4 Ų102.456%0.55749%0.492SS*.Hα-helixtrans-60.4-43.4175.5-171.5178.4177-177.40112.5E224 R225 K226 Y230 E231 D232E224-K228 PolarHBondContact O-N 3Å; R225-K228 PolarHBondContact O-N 3.14Å; K226-K228 VanDerWaalsContact C-N 3.32Å; K226-K228 PolarHBondContact O-N 2.79Å; K228-Y230 VanDerWaalsContact C-N 3.27Å; K228-Y230 PolarHBondContact O-N 3.35Å; K228-E231 PolarHBondContact O-N 3.33Å; K228-D232 WeakPolarHBondContact O-CB 3.32Å; K228-D232 PolarHBondContact O-N 3.49Å
229E82.2Confident81.9Confident93 Ų93104.4 Ų104.444%0.43549%0.491SS..Hα-helixtrans-58.9-36.5173.9-74.7-179.9-14000112.8R225 K226 Q227 R233R225-E229 PolarHBondContact O-N 2.93Å; K226-E229 PolarHBondContact O-N 3.05Å; Q227-E229 PolarHBondContact O-N 3.19Å; E229-R233 WeakPolarHBondContact O-CB 3.45Å; E229-R233 WeakPolarHBondContact O-CG 3.47Å; E229-R233 PolarHBondContact O-N 2.72Å; E229-R233 VanDerWaalsContact O-N 3.08Å; E229-R233 IonicContact OE2-NH2 3.17Å; E229-R233 PolarHBondContact OE2-NH2 2.83Å; E229-R233 VanDerWaalsContact OE2-NH2 3.09Å
230Y78.5Confident81.8Confident150 Ų150106.9 Ų106.959%0.58849%0.492SS*.Hα-helixtrans-73-37.1174.7-68.4-54.4000112.4K226 Q227 K228 L234K226-Y230 HydrophobicContact CB-CE2 4.32Å; K226-Y230 WeakPolarHBondContact O-CD2 3.36Å; K226-Y230 PolarHBondContact O-N 3.02Å; Q227-Y230 PolarHBondContact O-N 3.43Å; Q227-Y230 VanDerWaalsContact O-N 3.11Å; K228-Y230 VanDerWaalsContact C-N 3.27Å; K228-Y230 PolarHBondContact O-N 3.35Å; Y230-L234 WeakPolarHBondContact O-CB 3.47Å; Y230-L234 PolarHBondContact O-N 2.98Å
231E82Confident81.8Confident96 Ų96103.1 Ų103.145%0.44948%0.482SS..Hα-helixtrans-65-46174.7-72.9171.4-174.100111.4Q227 K228 L234 M235Q227-E231 HydrophobicContact CG-CG 4.44Å; Q227-E231 WeakPolarHBondContact CG-OE1 3.13Å; Q227-E231 PolarHBondContact NE2-OE1 2.76Å; Q227-E231 WeakPolarHBondContact O-CG 3.34Å; Q227-E231 PolarHBondContact O-N 2.76Å; K228-E231 PolarHBondContact O-N 3.33Å; E231-L234 PolarHBondContact O-N 3.2Å; E231-M235 WeakPolarHBondContact O-CG 3.19Å; E231-M235 PolarHBondContact O-N 2.81Å
232D85.9Confident81.9Confident93 Ų93103.3 Ų103.350%0.49748%0.483SS..Hα-helixtrans-61.8-44.5175.9-72.5-28.4000111K228 M235 E236K228-D232 WeakPolarHBondContact O-CB 3.32Å; K228-D232 PolarHBondContact O-N 3.49Å; D232-M235 PolarHBondContact O-N 2.68Å; D232-E236 PolarHBondContact O-N 3.47Å; D232-E236 VanDerWaalsContact O-N 3.12Å
233R81.9Confident82Confident153 Ų153107.2 Ų107.258%0.57749%0.488SS*.Hα-helixtrans-63.4-42.7173.9-74.1176.1-146.5-158.47.7112.7E229 M235 E236 M237E229-R233 WeakPolarHBondContact O-CB 3.45Å; E229-R233 WeakPolarHBondContact O-CG 3.47Å; E229-R233 PolarHBondContact O-N 2.72Å; E229-R233 VanDerWaalsContact O-N 3.08Å; E229-R233 IonicContact OE2-NH2 3.17Å; E229-R233 PolarHBondContact OE2-NH2 2.83Å; E229-R233 VanDerWaalsContact OE2-NH2 3.09Å; R233-M235 VanDerWaalsContact C-N 3.25Å; R233-M235 PolarHBondContact O-N 2.93Å; R233-E236 PolarHBondContact O-N 3.16Å; R233-M237 WeakPolarHBondContact O-CB 3.2Å; R233-M237 PolarHBondContact O-N 3.13Å
234L80.4Confident81.9Confident82 Ų82105.2 Ų105.243%0.42947%0.471SS..Hα-helixtrans-64.8-32.1178.6-178.863.5000111.6Y230 E231 M237 K238Y230-L234 WeakPolarHBondContact O-CB 3.47Å; Y230-L234 PolarHBondContact O-N 2.98Å; E231-L234 PolarHBondContact O-N 3.2Å; L234-M237 HydrophobicContact CD1-CE 4.12Å; L234-K238 HydrophobicContact CG-CD 4.48Å; L234-K238 WeakPolarHBondContact O-CB 3.35Å; L234-K238 WeakPolarHBondContact O-CD 3.3Å; L234-K238 WeakPolarHBondContact O-CG 3.44Å; L234-K238 PolarHBondContact O-N 3.28Å; L234-K238 VanDerWaalsContact O-N 3.1Å
235M86.1Confident81.9Confident122 Ų122105.1 Ų105.160%0.60147%0.469SS*.Hα-helixtrans-70.1-43.8174.2-75.5-65.7-69.800112.5E231 D232 R233 K239E231-M235 WeakPolarHBondContact O-CG 3.19Å; E231-M235 PolarHBondContact O-N 2.81Å; D232-M235 PolarHBondContact O-N 2.68Å; R233-M235 VanDerWaalsContact C-N 3.25Å; R233-M235 PolarHBondContact O-N 2.93Å; M235-K239 WeakPolarHBondContact O-CB 3.4Å; M235-K239 PolarHBondContact O-N 3.45Å
236E82.3Confident82Confident76 Ų76101.5 Ų101.536%0.35546%0.46SS..Hα-helixtrans-68.5-41.5175.6-163.363.8-153.300111.4D232 R233 K238 K239 E240 R243D232-E236 PolarHBondContact O-N 3.47Å; D232-E236 VanDerWaalsContact O-N 3.12Å; R233-E236 PolarHBondContact O-N 3.16Å; E236-K238 VanDerWaalsContact C-N 3.33Å; E236-K238 PolarHBondContact O-N 3.17Å; E236-K239 CarbonylContact O-C 3.55Å; E236-K239 WeakPolarHBondContact O-CA 3.43Å; E236-K239 WeakPolarHBondContact O-CB 3.38Å; E236-K239 PolarHBondContact O-N 3.39Å; E236-K239 WeakPolarHBondContact OE1-CE 3.38Å; E236-K239 IonicContact OE1-NZ 2.79Å; E236-K239 PolarHBondContact OE1-NZ 2.94Å; E236-K239 WeakPolarHBondContact OE2-CD 3.47Å; E236-K239 IonicContact OE2-NZ 3.18Å; E236-K239 PolarHBondContact OE2-NZ 3.08Å; E236-E240 PolarHBondContact O-N 3.16Å; E236-R243 IonicContact OE1-NH1 2.63Å
237M79.9Confident82Confident75 Ų75100.8 Ų100.837%0.36946%0.458SS..Hα-helixtrans-59.4-40.6176.2-167.9-169.888.900112.3R233 L234 K239 E240 M241 A349R233-M237 WeakPolarHBondContact O-CB 3.2Å; R233-M237 PolarHBondContact O-N 3.13Å; L234-M237 HydrophobicContact CD1-CE 4.12Å; M237-K239 VanDerWaalsContact C-N 3.32Å; M237-K239 PolarHBondContact O-N 2.97Å; M237-E240 PolarHBondContact O-N 3.26Å; M237-M241 WeakPolarHBondContact O-CB 3.35Å; M237-M241 PolarHBondContact O-N 3.43Å; M237-A349 HydrophobicContact CE-CB 4.47Å; M237-A349 HydrophobicContact CG-CB 4.17Å; M237-A349 HydrophobicContact SD-CB 3.93Å
238K81.1Confident82.2Confident108 Ų10898.4 Ų98.447%0.4745%0.448SS..Hα-helixtrans-62.2-38.9173-78.5168.3-179.2171.80112.5L234 E236 M241 E242L234-K238 HydrophobicContact CG-CD 4.48Å; L234-K238 WeakPolarHBondContact O-CB 3.35Å; L234-K238 WeakPolarHBondContact O-CD 3.3Å; L234-K238 WeakPolarHBondContact O-CG 3.44Å; L234-K238 PolarHBondContact O-N 3.28Å; L234-K238 VanDerWaalsContact O-N 3.1Å; E236-K238 VanDerWaalsContact C-N 3.33Å; E236-K238 PolarHBondContact O-N 3.17Å; K238-M241 PolarHBondContact O-N 3.03Å; K238-E242 PolarHBondContact O-N 3.43Å
239K85.7Confident82.2Confident96 Ų9696.2 Ų96.242%0.41744%0.442SS..Hα-helixtrans-72.4-34.2-179.8170.9179.6161.8-136.40112M235 E236 M237 R243M235-K239 WeakPolarHBondContact O-CB 3.4Å; M235-K239 PolarHBondContact O-N 3.45Å; E236-K239 CarbonylContact O-C 3.55Å; E236-K239 WeakPolarHBondContact O-CA 3.43Å; E236-K239 WeakPolarHBondContact O-CB 3.38Å; E236-K239 PolarHBondContact O-N 3.39Å; E236-K239 WeakPolarHBondContact OE1-CE 3.38Å; E236-K239 IonicContact OE1-NZ 2.79Å; E236-K239 PolarHBondContact OE1-NZ 2.94Å; E236-K239 WeakPolarHBondContact OE2-CD 3.47Å; E236-K239 IonicContact OE2-NZ 3.18Å; E236-K239 PolarHBondContact OE2-NZ 3.08Å; M237-K239 VanDerWaalsContact C-N 3.32Å; M237-K239 PolarHBondContact O-N 2.97Å; K239-R243 WeakPolarHBondContact O-CD 3.33Å; K239-R243 VanDerWaalsContact O-CG 3.27Å; K239-R243 WeakPolarHBondContact O-CG 3.5Å; K239-R243 PolarHBondContact O-N 3.13Å
240E80.2Confident82.2Confident112 Ų11295.5 Ų95.552%0.52344%0.441SS..Hα-helixtrans-68-44.2167.7-69-177.615100111.6E236 M237 E242 R243 A244E236-E240 PolarHBondContact O-N 3.16Å; M237-E240 PolarHBondContact O-N 3.26Å; E240-E242 PolarHBondContact O-N 3.45Å; E240-R243 WeakPolarHBondContact O-CB 3.3Å; E240-R243 PolarHBondContact O-N 3.47Å; E240-A244 WeakPolarHBondContact O-CB 3.28Å; E240-A244 PolarHBondContact O-N 3.4Å
241M78Confident82.3Confident89 Ų8988.7 Ų88.744%0.43842%0.416SS..Hα-helixtrans-58.9-43.8177.8-160.8-160.68300112.3M237 K238 K245 L346M237-M241 WeakPolarHBondContact O-CB 3.35Å; M237-M241 PolarHBondContact O-N 3.43Å; K238-M241 PolarHBondContact O-N 3.03Å; M241-K245 VanDerWaalsContact O-CB 3.24Å; M241-K245 WeakPolarHBondContact O-CB 3.47Å; M241-K245 PolarHBondContact O-N 2.89Å; M241-L346 HydrophobicContact CG-CD1 3.44Å; M241-L346 VanDerWaalsContact CG-CD1 3.44Å; M241-L346 HydrophobicContact SD-CD1 4.45Å
242E84.2Confident82.3Confident95 Ų9589.2 Ų89.244%0.44442%0.419SS..Hα-helixtrans-73.3-30.6180-162.165.2-159.700112.2K238 E240 K245 Q246K238-E242 PolarHBondContact O-N 3.43Å; E240-E242 PolarHBondContact O-N 3.45Å; E242-K245 IonicContact OE1-NZ 2.74Å; E242-K245 PolarHBondContact OE1-NZ 3.43Å; E242-K245 WeakPolarHBondContact OE2-CD 3.46Å; E242-K245 IonicContact OE2-NZ 2.7Å; E242-K245 PolarHBondContact OE2-NZ 2.83Å; E242-Q246 PolarHBondContact O-N 3.44Å
243R83.8Confident82.2Confident131 Ų13186.8 Ų86.849%0.49441%0.409SS..Hα-helixtrans-63.4-54168.7-77.6166.6169.6165.5-7.5111.7E236 K239 E240 K245 Q246 E247E236-R243 IonicContact OE1-NH1 2.63Å; K239-R243 WeakPolarHBondContact O-CD 3.33Å; K239-R243 VanDerWaalsContact O-CG 3.27Å; K239-R243 WeakPolarHBondContact O-CG 3.5Å; K239-R243 PolarHBondContact O-N 3.13Å; E240-R243 WeakPolarHBondContact O-CB 3.3Å; E240-R243 PolarHBondContact O-N 3.47Å; R243-K245 PolarHBondContact O-N 3.11Å; R243-Q246 PolarHBondContact O-N 2.75Å; R243-E247 WeakPolarHBondContact O-CG 3.47Å; R243-E247 PolarHBondContact O-N 3.43Å
244A80.6Confident82.2Confident15 Ų1581.1 Ų81.112%0.12439%0.392CS..Hα-helixtrans-58.3-36.5179.800000111.9E240 L248 A342E240-A244 WeakPolarHBondContact O-CB 3.28Å; E240-A244 PolarHBondContact O-N 3.4Å; A244-L248 VanDerWaalsContact O-CB 3.28Å; A244-L248 WeakPolarHBondContact O-CB 3.47Å; A244-L248 PolarHBondContact O-N 3.24Å; A244-A342 HydrophobicContact CB-CB 4.12Å
245K80.6Confident82.2Confident91 Ų9178.1 Ų78.140%0.39638%0.375SS..Hα-helixtrans-67.2-39.7173175.3-174.8163.7-1460113.2M241 E242 R243 I249M241-K245 VanDerWaalsContact O-CB 3.24Å; M241-K245 WeakPolarHBondContact O-CB 3.47Å; M241-K245 PolarHBondContact O-N 2.89Å; E242-K245 IonicContact OE1-NZ 2.74Å; E242-K245 PolarHBondContact OE1-NZ 3.43Å; E242-K245 WeakPolarHBondContact OE2-CD 3.46Å; E242-K245 IonicContact OE2-NZ 2.7Å; E242-K245 PolarHBondContact OE2-NZ 2.83Å; R243-K245 PolarHBondContact O-N 3.11Å; K245-I249 HydrophobicContact CG-CD1 4.44Å; K245-I249 WeakPolarHBondContact O-CG1 3.36Å; K245-I249 PolarHBondContact O-N 2.84Å; K245-I249 VanDerWaalsContact O-N 3.15Å
246Q84.2Confident82.2Confident93 Ų9380.3 Ų80.344%0.43538%0.377SS..Hα-helixtrans-67-46.7174.6-178.356.749.900111.1E242 R243 L248 I249 D250E242-Q246 PolarHBondContact O-N 3.44Å; R243-Q246 PolarHBondContact O-N 2.75Å; Q246-L248 VanDerWaalsContact C-N 3.26Å; Q246-L248 PolarHBondContact O-N 2.8Å; Q246-I249 WeakPolarHBondContact O-CB 3.23Å; Q246-I249 PolarHBondContact O-N 2.79Å; Q246-D250 VanDerWaalsContact NE2-CG 3.26Å; Q246-D250 PolarHBondContact NE2-OD1 2.86Å; Q246-D250 PolarHBondContact NE2-OD2 3.07Å; Q246-D250 PolarHBondContact O-N 3.21Å
247E81.5Confident82.2Confident108 Ų10883.7 Ų83.751%0.50539%0.387SS..Hα-helixtrans-58.9-37175.9-70171.2-166.100112R243 D250 A251R243-E247 WeakPolarHBondContact O-CG 3.47Å; R243-E247 PolarHBondContact O-N 3.43Å; E247-D250 PolarHBondContact O-N 2.84Å; E247-A251 VanDerWaalsContact O-CB 3.27Å; E247-A251 WeakPolarHBondContact O-CB 3.49Å; E247-A251 PolarHBondContact O-N 3.4Å
248L81.3Confident82.3Confident60 Ų6080.9 Ų80.931%0.31437%0.373SS..Hα-helixtrans-63.6-41.4172.9176.963000112.9A244 Q246 Q252 Q339A244-L248 VanDerWaalsContact O-CB 3.28Å; A244-L248 WeakPolarHBondContact O-CB 3.47Å; A244-L248 PolarHBondContact O-N 3.24Å; Q246-L248 VanDerWaalsContact C-N 3.26Å; Q246-L248 PolarHBondContact O-N 2.8Å; L248-Q252 WeakPolarHBondContact O-CB 3.36Å; L248-Q252 VanDerWaalsContact O-CG 3.29Å; L248-Q252 WeakPolarHBondContact O-CG 3.44Å; L248-Q252 PolarHBondContact O-N 3.01Å; L248-Q339 HydrophobicContact CD1-CB 4.47Å; L248-Q339 HydrophobicContact CD1-CG 3.79Å; L248-Q339 VanDerWaalsContact CD1-NE2 3.34Å
249I85.6Confident82.4Confident82 Ų8280.8 Ų80.842%0.42137%0.374SS..Hα-helixtrans-66.1-44.1176-69.6163.6000110.2K245 Q246 Q252 S253K245-I249 HydrophobicContact CG-CD1 4.44Å; K245-I249 WeakPolarHBondContact O-CG1 3.36Å; K245-I249 PolarHBondContact O-N 2.84Å; K245-I249 VanDerWaalsContact O-N 3.15Å; Q246-I249 WeakPolarHBondContact O-CB 3.23Å; Q246-I249 PolarHBondContact O-N 2.79Å; I249-Q252 PolarHBondContact O-N 3.01Å; I249-S253 PolarHBondContact O-N 3.42Å
250D83.1Confident82.4Confident78 Ų7880.2 Ų80.242%0.41738%0.376SS..Hα-helixtrans-65-42.5-179.9-66.6-31.1000111.2Q246 E247 S253 T254Q246-D250 VanDerWaalsContact NE2-CG 3.26Å; Q246-D250 PolarHBondContact NE2-OD1 2.86Å; Q246-D250 PolarHBondContact NE2-OD2 3.07Å; Q246-D250 PolarHBondContact O-N 3.21Å; E247-D250 PolarHBondContact O-N 2.84Å; D250-S253 WeakPolarHBondContact O-CB 3.26Å; D250-S253 PolarHBondContact O-N 3.28Å; D250-S253 VanDerWaalsContact O-N 3.11Å; D250-S253 PolarHBondContact O-OG 3.47Å; D250-T254 PolarHBondContact O-N 3.43Å; D250-T254 VanDerWaalsContact O-N 3.11Å
251A80.2Confident82.4Confident8 Ų876.6 Ų76.67%0.06636%0.363CS..Hα-helixtrans-63.8-39.6173.500000113.2E247 S253 T254 I255 A335 Q339E247-A251 VanDerWaalsContact O-CB 3.27Å; E247-A251 WeakPolarHBondContact O-CB 3.49Å; E247-A251 PolarHBondContact O-N 3.4Å; A251-S253 VanDerWaalsContact C-N 3.26Å; A251-S253 PolarHBondContact O-N 2.95Å; A251-T254 PolarHBondContact O-N 2.97Å; A251-T254 PolarHBondContact O-OG1 3.08Å; A251-I255 WeakPolarHBondContact O-CD1 3.15Å; A251-I255 VanDerWaalsContact O-CG1 3.26Å; A251-I255 WeakPolarHBondContact O-CG1 3.46Å; A251-I255 PolarHBondContact O-N 3.09Å; A251-A335 HydrophobicContact CB-CB 4.06Å; A251-Q339 HydrophobicContact CB-CB 4.46Å
252Q81.6Confident82.6Confident106 Ų10674.7 Ų74.750%0.49535%0.354SS..Hα-helixtrans-62.5-35.2171.4-75.9175.8-0.300111.6L248 I249 R256L248-Q252 WeakPolarHBondContact O-CB 3.36Å; L248-Q252 VanDerWaalsContact O-CG 3.29Å; L248-Q252 WeakPolarHBondContact O-CG 3.44Å; L248-Q252 PolarHBondContact O-N 3.01Å; I249-Q252 PolarHBondContact O-N 3.01Å; Q252-R256 WeakPolarHBondContact O-CB 3.23Å; Q252-R256 PolarHBondContact O-N 3.46Å; Q252-R256 VanDerWaalsContact O-N 3.16Å
253S84.4Confident82.7Confident42 Ų4277.2 Ų77.229%0.29436%0.364SS..Hα-helixtrans-70.3-29.7178.191.10000113.9I249 D250 A251 R257I249-S253 PolarHBondContact O-N 3.42Å; D250-S253 WeakPolarHBondContact O-CB 3.26Å; D250-S253 PolarHBondContact O-N 3.28Å; D250-S253 VanDerWaalsContact O-N 3.11Å; D250-S253 PolarHBondContact O-OG 3.47Å; A251-S253 VanDerWaalsContact C-N 3.26Å; A251-S253 PolarHBondContact O-N 2.95Å; S253-R257 WeakPolarHBondContact O-CG 3.3Å; S253-R257 PolarHBondContact O-N 2.88Å; S253-R257 PolarHBondContact O-NE 3.42Å; S253-R257 PolarHBondContact OG-NH2 2.98Å
254T81Confident82.7Confident35 Ų3576.7 Ų76.722%0.21537%0.367CS..Hα-helixtrans-82-42176.753.40000111.5D250 A251 R256 R257 L258D250-T254 PolarHBondContact O-N 3.43Å; D250-T254 VanDerWaalsContact O-N 3.11Å; A251-T254 PolarHBondContact O-N 2.97Å; A251-T254 PolarHBondContact O-OG1 3.08Å; T254-R256 VanDerWaalsContact C-N 3.27Å; T254-R256 PolarHBondContact O-N 2.73Å; T254-R257 PolarHBondContact O-N 3.23Å; T254-R257 VanDerWaalsContact O-N 3.17Å; T254-L258 PolarHBondContact O-N 3.49Å; T254-L258 VanDerWaalsContact O-N 3.16Å
255I80.9Confident82.8Confident18 Ų1876.6 Ų76.69%0.09236%0.364CS..Hα-helixtrans-50.9-48.9171.2-70.5162.7000110.4A251 R257 L258 E259 V332 R336A251-I255 WeakPolarHBondContact O-CD1 3.15Å; A251-I255 VanDerWaalsContact O-CG1 3.26Å; A251-I255 WeakPolarHBondContact O-CG1 3.46Å; A251-I255 PolarHBondContact O-N 3.09Å; I255-R257 PolarHBondContact O-N 3.1Å; I255-L258 WeakPolarHBondContact O-CB 3.09Å; I255-L258 PolarHBondContact O-N 3.13Å; I255-E259 WeakPolarHBondContact O-CG 3.41Å; I255-E259 PolarHBondContact O-N 3.45Å; I255-V332 HydrophobicContact CG1-CG1 3.86Å; I255-R336 HydrophobicContact CD1-CG 3.97Å; I255-R336 HydrophobicContact CG1-CG 4.35Å
256R85.2Confident83Confident168 Ų16877.7 Ų77.763%0.63437%0.371SS*.Hα-helixtrans-63.2-41.1-179.5-175174.6175.31711.4113.6Q252 T254 L258 E259 D260Q252-R256 WeakPolarHBondContact O-CB 3.23Å; Q252-R256 PolarHBondContact O-N 3.46Å; Q252-R256 VanDerWaalsContact O-N 3.16Å; T254-R256 VanDerWaalsContact C-N 3.27Å; T254-R256 PolarHBondContact O-N 2.73Å; R256-L258 VanDerWaalsContact C-N 3.25Å; R256-L258 PolarHBondContact O-N 3.41Å; R256-E259 PolarHBondContact O-N 2.77Å; R256-D260 PolarHBondContact O-N 3Å
257R83.1Confident83Confident147 Ų14774.9 Ų74.956%0.55537%0.367SS*.Hα-helixtrans-60.5-36.2176.7-78.7177.7-105.6179.8-7.3112S253 T254 I255 S261S253-R257 WeakPolarHBondContact O-CG 3.3Å; S253-R257 PolarHBondContact O-N 2.88Å; S253-R257 PolarHBondContact O-NE 3.42Å; S253-R257 PolarHBondContact OG-NH2 2.98Å; T254-R257 PolarHBondContact O-N 3.23Å; T254-R257 VanDerWaalsContact O-N 3.17Å; I255-R257 PolarHBondContact O-N 3.1Å; R257-S261 WeakPolarHBondContact O-CB 3.49Å; R257-S261 PolarHBondContact O-N 3.22Å; R257-S261 PolarHBondContact O-OG 2.71Å
258L82.4Confident83.1Confident16 Ų1671 Ų718%0.08435%0.353CS..Hα-helixtrans-70.7-41.7173.6168.3131.6000112.4T254 I255 R256 D260 S261 L262 L328 Q329 V332T254-L258 PolarHBondContact O-N 3.49Å; T254-L258 VanDerWaalsContact O-N 3.16Å; I255-L258 WeakPolarHBondContact O-CB 3.09Å; I255-L258 PolarHBondContact O-N 3.13Å; R256-L258 VanDerWaalsContact C-N 3.25Å; R256-L258 PolarHBondContact O-N 3.41Å; L258-D260 VanDerWaalsContact C-N 3.31Å; L258-D260 PolarHBondContact O-N 3.25Å; L258-S261 PolarHBondContact O-N 3.09Å; L258-L262 HydrophobicContact CD1-CD1 4.47Å; L258-L262 HydrophobicContact CD2-CD1 3.56Å; L258-L262 HydrophobicContact CG-CD1 3.78Å; L258-L262 HydrophobicContact CG-CG 4.3Å; L258-L262 WeakPolarHBondContact O-CB 3.49Å; L258-L262 WeakPolarHBondContact O-CG 3.18Å; L258-L262 PolarHBondContact O-N 3.42Å; L258-L328 HydrophobicContact CD1-CB 4.03Å; L258-L328 VanDerWaalsContact CD1-O 3.3Å; L258-L328 WeakPolarHBondContact CD1-O 3.18Å; L258-Q329 VanDerWaalsContact CD1-CA 3.43Å; L258-Q329 HydrophobicContact CD1-CB 4.12Å; L258-Q329 HydrophobicContact CD1-CG 3.59Å; L258-V332 HydrophobicContact CB-CG2 3.76Å; L258-V332 HydrophobicContact CD1-CB 4.07Å; L258-V332 HydrophobicContact CD1-CG2 3.96Å; L258-V332 HydrophobicContact CD2-CG1 4.27Å; L258-V332 HydrophobicContact CD2-CG2 4.42Å; L258-V332 HydrophobicContact CG-CG2 4.27Å
259E82.8Confident83.2Confident107 Ų10772 Ų7250%0.536%0.356SS..Hα-helixtrans-59.1-42.8175.7-71.2173.9165.600111.6I255 R256 K263I255-E259 WeakPolarHBondContact O-CG 3.41Å; I255-E259 PolarHBondContact O-N 3.45Å; R256-E259 PolarHBondContact O-N 2.77Å; E259-K263 WeakPolarHBondContact O-CB 3.36Å; E259-K263 PolarHBondContact O-N 3.44Å
260D85.5Confident83.2Confident84 Ų8474 Ų7445%0.44936%0.364SS..Hα-helixtrans-65.5-43.6173.7-71.6-41.3000111.7R256 L258 K263 E264R256-D260 PolarHBondContact O-N 3Å; L258-D260 VanDerWaalsContact C-N 3.31Å; L258-D260 PolarHBondContact O-N 3.25Å; D260-K263 WeakPolarHBondContact O-CB 3Å; D260-K263 PolarHBondContact O-N 3.48Å; D260-E264 PolarHBondContact O-N 3.46Å
261S80.9Confident83.2Confident35 Ų3575 Ų7525%0.24537%0.366CS..Hα-helixtrans-64.8-42.3178.9-57.90000113.3R257 L258 K263 E264 L265R257-S261 WeakPolarHBondContact O-CB 3.49Å; R257-S261 PolarHBondContact O-N 3.22Å; R257-S261 PolarHBondContact O-OG 2.71Å; L258-S261 PolarHBondContact O-N 3.09Å; S261-K263 VanDerWaalsContact C-N 3.26Å; S261-K263 PolarHBondContact O-N 3.05Å; S261-E264 PolarHBondContact O-N 3.27Å; S261-L265 WeakPolarHBondContact O-CB 3.27Å; S261-L265 PolarHBondContact O-N 3.31Å
262L81.2Confident83.4Confident49 Ų4975.5 Ų75.526%0.25737%0.367SS..Hα-helixtrans-62.2-36.4175.2-80.2166.4000111.5L258 L265 Q266 T325L258-L262 HydrophobicContact CD1-CD1 4.47Å; L258-L262 HydrophobicContact CD2-CD1 3.56Å; L258-L262 HydrophobicContact CG-CD1 3.78Å; L258-L262 HydrophobicContact CG-CG 4.3Å; L258-L262 WeakPolarHBondContact O-CB 3.49Å; L258-L262 WeakPolarHBondContact O-CG 3.18Å; L258-L262 PolarHBondContact O-N 3.42Å; L262-L265 PolarHBondContact O-N 2.77Å; L262-Q266 WeakPolarHBondContact O-CB 3.2Å; L262-Q266 WeakPolarHBondContact O-CG 3.48Å; L262-Q266 PolarHBondContact O-N 2.93Å; L262-T325 HydrophobicContact CD2-CG2 3.54Å; L262-T325 HydrophobicContact CG-CG2 3.93Å
263K86.2Confident83.5Confident149 Ų14973.1 Ų73.165%0.64837%0.366SS*.Hα-helixtrans-70.7-39.7178.1-173.4-179.2177.9-174.50112.1E259 D260 S261 G267E259-K263 WeakPolarHBondContact O-CB 3.36Å; E259-K263 PolarHBondContact O-N 3.44Å; D260-K263 WeakPolarHBondContact O-CB 3Å; D260-K263 PolarHBondContact O-N 3.48Å; S261-K263 VanDerWaalsContact C-N 3.26Å; S261-K263 PolarHBondContact O-N 3.05Å; K263-G267 PolarHBondContact O-N 3.34Å
264E83.8Confident83.5Confident120 Ų12077.1 Ų77.156%0.56138%0.378SS*.Hα-helixtrans-59.3-46.7169-80-164.7-159.500111.8D260 S261 G267 A268 K321D260-E264 PolarHBondContact O-N 3.46Å; S261-E264 PolarHBondContact O-N 3.27Å; E264-G267 PolarHBondContact O-N 3.06Å; E264-G267 VanDerWaalsContact O-N 3.16Å; E264-A268 PolarHBondContact O-N 2.9Å; E264-K321 IonicContact OE2-NZ 2.72Å; E264-K321 PolarHBondContact OE2-NZ 3.39Å
265L83.6Confident83.6Confident13 Ų1379.5 Ų79.57%0.06838%0.383CS..Hα-helixtrans-64.6-42.9-177.9-176.1132.5000112.1S261 L262 G267 A268 Q269 K321 D322S261-L265 WeakPolarHBondContact O-CB 3.27Å; S261-L265 PolarHBondContact O-N 3.31Å; L262-L265 PolarHBondContact O-N 2.77Å; L265-G267 VanDerWaalsContact C-N 3.31Å; L265-G267 PolarHBondContact O-N 2.92Å; L265-A268 PolarHBondContact O-N 3.15Å; L265-Q269 WeakPolarHBondContact O-CB 3.22Å; L265-Q269 WeakPolarHBondContact O-CG 3.28Å; L265-Q269 PolarHBondContact O-N 3.27Å; L265-K321 HydrophobicContact CD1-CB 4.13Å; L265-D322 HydrophobicContact CD1-CB 4.18Å
266Q84.1Confident83.5Confident113 Ų11381.6 Ų81.653%0.52839%0.393SS..Hα-helixtrans-61.3-38.6171.9-75178.6-000112.2L262 Q270L262-Q266 WeakPolarHBondContact O-CB 3.2Å; L262-Q266 WeakPolarHBondContact O-CG 3.48Å; L262-Q266 PolarHBondContact O-N 2.93Å; Q266-Q270 WeakPolarHBondContact O-CG 3.47Å; Q266-Q270 PolarHBondContact O-N 3.16Å
267G85.5Confident83.4Confident35 Ų3577.9 Ų77.936%0.36138%0.383SS..Hα-helixtrans-61.3-49.3173.800000112.4K263 E264 L265 Q269 Q270 E271K263-G267 PolarHBondContact O-N 3.34Å; E264-G267 PolarHBondContact O-N 3.06Å; E264-G267 VanDerWaalsContact O-N 3.16Å; L265-G267 VanDerWaalsContact C-N 3.31Å; L265-G267 PolarHBondContact O-N 2.92Å; G267-Q269 PolarHBondContact O-N 3.21Å; G267-Q270 PolarHBondContact O-N 2.8Å; G267-E271 PolarHBondContact O-N 3.38Å
268A83.5Confident83.4Confident26 Ų2675.7 Ų75.722%0.21538%0.379CS..Hα-helixtrans-62.6-41.4178.500000112.4E264 L265 Q270 E271 L272 I318E264-A268 PolarHBondContact O-N 2.9Å; L265-A268 PolarHBondContact O-N 3.15Å; A268-Q270 PolarHBondContact O-N 3.38Å; A268-E271 PolarHBondContact O-N 3.12Å; A268-L272 WeakPolarHBondContact O-CB 3.48Å; A268-L272 PolarHBondContact O-N 2.99Å; A268-I318 HydrophobicContact CB-CD1 4.09Å; A268-I318 HydrophobicContact CB-CG1 3.93Å; A268-I318 WeakPolarHBondContact O-CD1 3.41Å
269Q83.3Confident83.4Confident82 Ų8275.7 Ų75.738%0.38338%0.379SS..Hα-helixtrans-63.3-38.6174.7-73.4179.7-7.600112.3L265 G267 A273 I318 D322L265-Q269 WeakPolarHBondContact O-CB 3.22Å; L265-Q269 WeakPolarHBondContact O-CG 3.28Å; L265-Q269 PolarHBondContact O-N 3.27Å; G267-Q269 PolarHBondContact O-N 3.21Å; Q269-A273 WeakPolarHBondContact O-CB 3.32Å; Q269-A273 PolarHBondContact O-N 2.86Å; Q269-I318 HydrophobicContact CG-CG2 3.93Å; Q269-D322 PolarHBondContact NE2-OD2 2.93Å
270Q85.2Confident83.2Confident122 Ų12275.6 Ų75.657%0.5738%0.379SS*.Hα-helixtrans-68.7-33.6173.8-73.317923.500113.1Q266 G267 A268 K274Q266-Q270 WeakPolarHBondContact O-CG 3.47Å; Q266-Q270 PolarHBondContact O-N 3.16Å; G267-Q270 PolarHBondContact O-N 2.8Å; A268-Q270 PolarHBondContact O-N 3.38Å; Q270-K274 WeakPolarHBondContact O-CG 3.24Å; Q270-K274 PolarHBondContact O-N 3.14Å
271E83.5Confident83.1Confident99 Ų9975.7 Ų75.746%0.46338%0.375SS..Hα-helixtrans-72.1-40.6176.3-159.7-175.413400111.5G267 A268 K274 R275G267-E271 PolarHBondContact O-N 3.38Å; A268-E271 PolarHBondContact O-N 3.12Å; E271-K274 PolarHBondContact O-N 2.8Å; E271-R275 PolarHBondContact O-N 3.4Å; E271-R275 VanDerWaalsContact O-N 3.16Å; E271-R275 IonicContact OE1-CZ 2.72Å; E271-R275 IonicContact OE1-NH1 3.08Å; E271-R275 PolarHBondContact OE1-NH1 2.75Å; E271-R275 IonicContact OE1-NH2 2.71Å; E271-R275 PolarHBondContact OE1-NH2 2.94Å
272L83.6Confident83Confident19 Ų1975.1 Ų75.110%0.09937%0.369CS..Hα-helixtrans-58.5-49.7170.917666.5000111.3A268 K274 R275 E276 I311 V314 R315 I318A268-L272 WeakPolarHBondContact O-CB 3.48Å; A268-L272 PolarHBondContact O-N 2.99Å; L272-K274 PolarHBondContact O-N 2.58Å; L272-R275 WeakPolarHBondContact O-CB 3.34Å; L272-R275 PolarHBondContact O-N 2.96Å; L272-E276 HydrophobicContact CD1-CG 4.24Å; L272-E276 WeakPolarHBondContact CD1-OE1 3.37Å; L272-E276 HydrophobicContact CG-CG 4.41Å; L272-E276 VanDerWaalsContact CG-OE1 3.28Å; L272-E276 WeakPolarHBondContact CG-OE1 3.29Å; L272-E276 WeakPolarHBondContact O-CG 3.49Å; L272-E276 PolarHBondContact O-N 3.48Å; L272-I311 HydrophobicContact CD1-CG2 4.08Å; L272-V314 HydrophobicContact CB-CG1 4.45Å; L272-V314 HydrophobicContact CD1-CB 4.45Å; L272-V314 HydrophobicContact CD1-CG1 4.13Å; L272-R315 HydrophobicContact CD1-CG 3.86Å; L272-R315 HydrophobicContact CD2-CG 3.71Å; L272-R315 HydrophobicContact CG-CG 4.43Å; L272-I318 HydrophobicContact CB-CD1 3.67Å; L272-I318 HydrophobicContact CD2-CD1 3.75Å; L272-I318 HydrophobicContact CG-CD1 4.22Å
273A84.2Confident82.7Confident57 Ų5773.6 Ų73.647%0.47137%0.365SS..Hα-helixtrans-57.5-35-179.900000112.9Q269 E277Q269-A273 WeakPolarHBondContact O-CB 3.32Å; Q269-A273 PolarHBondContact O-N 2.86Å; A273-E277 WeakPolarHBondContact O-CB 3.45Å; A273-E277 PolarHBondContact O-N 2.71Å
274K84.7Confident82.4Confident126 Ų12670.7 Ų70.755%0.54835%0.35SS..Hα-helixtrans-68.1-44.6173.6-70.9168.7-174.9171.60112.5Q270 E271 L272 E276 E277 E278Q270-K274 WeakPolarHBondContact O-CG 3.24Å; Q270-K274 PolarHBondContact O-N 3.14Å; E271-K274 PolarHBondContact O-N 2.8Å; L272-K274 PolarHBondContact O-N 2.58Å; K274-E276 VanDerWaalsContact C-N 3.28Å; K274-E276 PolarHBondContact O-N 2.92Å; K274-E277 PolarHBondContact O-N 3.47Å; K274-E278 WeakPolarHBondContact O-CG 3.34Å; K274-E278 PolarHBondContact O-N 3.26Å
275R81.5Confident82Confident84 Ų8471.9 Ų71.932%0.31735%0.35SS..Hα-helixtrans-59.5-40.4175-70.9-175.517398.210.9111.5E271 L272 E278 V279 I311E271-R275 PolarHBondContact O-N 3.4Å; E271-R275 VanDerWaalsContact O-N 3.16Å; E271-R275 IonicContact OE1-CZ 2.72Å; E271-R275 IonicContact OE1-NH1 3.08Å; E271-R275 PolarHBondContact OE1-NH1 2.75Å; E271-R275 IonicContact OE1-NH2 2.71Å; E271-R275 PolarHBondContact OE1-NH2 2.94Å; L272-R275 WeakPolarHBondContact O-CB 3.34Å; L272-R275 PolarHBondContact O-N 2.96Å; R275-E278 PolarHBondContact O-N 2.91Å; R275-V279 PolarHBondContact O-N 3.41Å; R275-I311 HydrophobicContact CB-CD1 4.11Å; R275-I311 HydrophobicContact CB-CG1 3.89Å
276E80Confident81.4Confident62 Ų6273 Ų7329%0.2936%0.356SS..Hα-helixtrans-65.8-42.3176.2-68.2-178.1-166.900112L272 K274 E278 V279 E280 I311 R315L272-E276 HydrophobicContact CD1-CG 4.24Å; L272-E276 WeakPolarHBondContact CD1-OE1 3.37Å; L272-E276 HydrophobicContact CG-CG 4.41Å; L272-E276 VanDerWaalsContact CG-OE1 3.28Å; L272-E276 WeakPolarHBondContact CG-OE1 3.29Å; L272-E276 WeakPolarHBondContact O-CG 3.49Å; L272-E276 PolarHBondContact O-N 3.48Å; K274-E276 VanDerWaalsContact C-N 3.28Å; K274-E276 PolarHBondContact O-N 2.92Å; E276-E278 VanDerWaalsContact C-N 3.35Å; E276-E278 PolarHBondContact O-N 2.91Å; E276-V279 PolarHBondContact O-N 3.21Å; E276-E280 PolarHBondContact O-N 3.19Å; E276-I311 HydrophobicContact CG-CD1 4.11Å; E276-I311 HydrophobicContact CG-CG2 4.06Å; E276-R315 IonicContact OE1-CZ 3.18Å; E276-R315 IonicContact OE1-NE 3.95Å; E276-R315 PolarHBondContact OE1-NE 2.88Å; E276-R315 IonicContact OE1-NH2 3.57Å; E276-R315 PolarHBondContact OE1-NH2 3.28Å; E276-R315 IonicContact OE2-CZ 2.68Å; E276-R315 IonicContact OE2-NH2 3.38Å; E276-R315 PolarHBondContact OE2-NH2 3.45Å
277E83.1Confident80.7Confident91 Ų9175.6 Ų75.643%0.42537%0.365SS..Hα-helixtrans-64.5-36.3174.4-158.4-156.416800112.5A273 K274 E280 K281A273-E277 WeakPolarHBondContact O-CB 3.45Å; A273-E277 PolarHBondContact O-N 2.71Å; K274-E277 PolarHBondContact O-N 3.47Å; E277-E280 PolarHBondContact O-N 3.16Å; E277-K281 WeakPolarHBondContact O-CB 3.33Å; E277-K281 WeakPolarHBondContact O-CD 3.44Å; E277-K281 VanDerWaalsContact O-CG 3.23Å; E277-K281 WeakPolarHBondContact O-CG 3.42Å; E277-K281 PolarHBondContact O-N 2.9Å; E277-K281 WeakPolarHBondContact OE1-CE 3.39Å; E277-K281 IonicContact OE1-NZ 3.97Å; E277-K281 PolarHBondContact OE1-NZ 3.46Å; E277-K281 IonicContact OE2-NZ 2.75Å; E277-K281 PolarHBondContact OE2-NZ 2.82Å
278E81.9Confident79.8Confident101 Ų10180.5 Ų80.547%0.47238%0.379SS..Hα-helixtrans-63.6-44.6173.6-76.2176.3-169.400111.9K274 R275 E276 K281 L282K274-E278 WeakPolarHBondContact O-CG 3.34Å; K274-E278 PolarHBondContact O-N 3.26Å; R275-E278 PolarHBondContact O-N 2.91Å; E276-E278 VanDerWaalsContact C-N 3.35Å; E276-E278 PolarHBondContact O-N 2.91Å; E278-K281 WeakPolarHBondContact O-CB 3.4Å; E278-K281 PolarHBondContact O-N 3.41Å; E278-L282 WeakPolarHBondContact O-CG 3.49Å; E278-L282 PolarHBondContact O-N 3.32Å
279V82.3Confident78.8Confident16 Ų1684.1 Ų84.110%0.09739%0.391CS..Hα-helixtrans-65.9-39.5174.7171.40000111.6R275 E276 K281 L282 G283 I304 R307 E308 I311R275-V279 PolarHBondContact O-N 3.41Å; E276-V279 PolarHBondContact O-N 3.21Å; V279-K281 VanDerWaalsContact C-N 3.3Å; V279-K281 PolarHBondContact O-N 2.75Å; V279-L282 PolarHBondContact O-N 3.33Å; V279-G283 PolarHBondContact O-N 2.99Å; V279-I304 HydrophobicContact CG1-CG2 4.26Å; V279-R307 HydrophobicContact CG2-CB 3.41Å; V279-R307 VanDerWaalsContact CG2-CB 3.41Å; V279-R307 HydrophobicContact CG2-CG 4.3Å; V279-E308 HydrophobicContact CG1-CG 4.05Å; V279-I311 HydrophobicContact CB-CD1 4.14Å; V279-I311 HydrophobicContact CG2-CD1 3.57Å
280E80.6Confident77.5Confident105 Ų10588.8 Ų88.849%0.49141%0.412SS..Hα-helixtrans-64.5-33.7174.7-156.5-147.9168.400112.2E276 E277 R284E276-E280 PolarHBondContact O-N 3.19Å; E277-E280 PolarHBondContact O-N 3.16Å; E280-R284 PolarHBondContact O-N 2.94Å; E280-R284 PolarHBondContact O-NE 3.19Å; E280-R284 IonicContact OE1-CZ 2.69Å; E280-R284 IonicContact OE1-NH1 2.68Å; E280-R284 PolarHBondContact OE1-NH1 2.85Å; E280-R284 IonicContact OE1-NH2 3.49Å; E280-R284 IonicContact OE2-CZ 2.98Å; E280-R284 VanDerWaalsContact OE2-CZ 3.31Å; E280-R284 IonicContact OE2-NH1 3.95Å; E280-R284 PolarHBondContact OE2-NH1 3.05Å; E280-R284 IonicContact OE2-NH2 2.87Å; E280-R284 PolarHBondContact OE2-NH2 2.92Å
281K82.3Confident76.1Confident86 Ų8692.3 Ų92.337%0.37443%0.429SS..Hα-helixtrans-68.1-42.5172.9-75.5162.8-176.5163.30112.2E277 E278 V279 R284 R285E277-K281 WeakPolarHBondContact O-CB 3.33Å; E277-K281 WeakPolarHBondContact O-CD 3.44Å; E277-K281 VanDerWaalsContact O-CG 3.23Å; E277-K281 WeakPolarHBondContact O-CG 3.42Å; E277-K281 PolarHBondContact O-N 2.9Å; E277-K281 WeakPolarHBondContact OE1-CE 3.39Å; E277-K281 IonicContact OE1-NZ 3.97Å; E277-K281 PolarHBondContact OE1-NZ 3.46Å; E277-K281 IonicContact OE2-NZ 2.75Å; E277-K281 PolarHBondContact OE2-NZ 2.82Å; E278-K281 WeakPolarHBondContact O-CB 3.4Å; E278-K281 PolarHBondContact O-N 3.41Å; V279-K281 VanDerWaalsContact C-N 3.3Å; V279-K281 PolarHBondContact O-N 2.75Å; K281-R284 PolarHBondContact O-N 2.7Å; K281-R285 PolarHBondContact O-N 2.83Å; K281-R285 VanDerWaalsContact O-N 3.16Å
282L78.6Confident74.8Confident22 Ų2289.9 Ų89.912%0.11542%0.418CS..Hα-helixtrans-64.9-44.3175-67.8165000111.3E278 V279 R284 R285 L286 I304 R307E278-L282 WeakPolarHBondContact O-CG 3.49Å; E278-L282 PolarHBondContact O-N 3.32Å; V279-L282 PolarHBondContact O-N 3.33Å; L282-R284 PolarHBondContact O-N 2.98Å; L282-R285 PolarHBondContact O-N 3.08Å; L282-L286 PolarHBondContact O-N 2.97Å; L282-L286 VanDerWaalsContact O-N 3.08Å; L282-I304 HydrophobicContact CB-CD1 4.01Å; L282-I304 HydrophobicContact CB-CG1 3.75Å; L282-R307 VanDerWaalsContact CD1-NH1 3.3Å
283G75.7Confident73.9Confident17 Ų1794 Ų9418%0.17544%0.441CS..Hα-helixtrans-68.4-11.717500000115.1V279 K287V279-G283 PolarHBondContact O-N 2.99Å; G283-K287 VanDerWaalsContact O-CD 3.3Å; G283-K287 WeakPolarHBondContact O-CD 3.3Å; G283-K287 WeakPolarHBondContact O-CE 3.43Å; G283-K287 WeakPolarHBondContact O-CG 3.43Å
284R78.7Confident73.2Confident89 Ų8997 Ų9734%0.33645%0.447SS..Hα-helixtrans-82.7-50.1165.7-87.8-179.5-75.9-118.1-6.7111.7E280 K281 L282 L286 K287 E288E280-R284 PolarHBondContact O-N 2.94Å; E280-R284 PolarHBondContact O-NE 3.19Å; E280-R284 IonicContact OE1-CZ 2.69Å; E280-R284 IonicContact OE1-NH1 2.68Å; E280-R284 PolarHBondContact OE1-NH1 2.85Å; E280-R284 IonicContact OE1-NH2 3.49Å; E280-R284 IonicContact OE2-CZ 2.98Å; E280-R284 VanDerWaalsContact OE2-CZ 3.31Å; E280-R284 IonicContact OE2-NH1 3.95Å; E280-R284 PolarHBondContact OE2-NH1 3.05Å; E280-R284 IonicContact OE2-NH2 2.87Å; E280-R284 PolarHBondContact OE2-NH2 2.92Å; K281-R284 PolarHBondContact O-N 2.7Å; L282-R284 PolarHBondContact O-N 2.98Å; R284-L286 VanDerWaalsContact C-N 3.29Å; R284-L286 PolarHBondContact O-N 2.92Å; R284-K287 WeakPolarHBondContact O-CA 3.25Å; R284-K287 WeakPolarHBondContact O-CB 3.41Å; R284-K287 PolarHBondContact O-N 2.87Å; R284-E288 WeakPolarHBondContact O-CG 3.22Å; R284-E288 PolarHBondContact O-N 3.44Å
285R75.4Confident72.5Confident144 Ų14495.9 Ų95.954%0.54345%0.447SS..Hα-helixtrans-52.3-47.1175.9-69.7-177.9-175167.60.8112.3K281 L282 K287 E288 E289K281-R285 PolarHBondContact O-N 2.83Å; K281-R285 VanDerWaalsContact O-N 3.16Å; L282-R285 PolarHBondContact O-N 3.08Å; R285-K287 PolarHBondContact O-N 3.13Å; R285-E288 PolarHBondContact O-N 2.94Å; R285-E289 PolarHBondContact O-N 3.39Å
286L71.9Confident71.8Confident37 Ų3796.9 Ų96.919%0.19446%0.456CS..Hα-helixtrans-55.4-21.5176-171.569000114.5L282 R284 K297 L300 E301 I304L282-L286 PolarHBondContact O-N 2.97Å; L282-L286 VanDerWaalsContact O-N 3.08Å; R284-L286 VanDerWaalsContact C-N 3.29Å; R284-L286 PolarHBondContact O-N 2.92Å; L286-K297 HydrophobicContact CD1-CG 3.71Å; L286-L300 HydrophobicContact CD1-CB 3.99Å; L286-E301 HydrophobicContact CD1-CG 4.02Å; L286-E301 HydrophobicContact CD2-CG 3.61Å; L286-E301 HydrophobicContact CG-CG 4.45Å; L286-I304 HydrophobicContact CB-CD1 4.43Å; L286-I304 HydrophobicContact CD2-CD1 3.88Å
287K69.7Low71.3Confident168 Ų16898.4 Ų98.473%0.7346%0.461SS*.Hα-helixtrans-100-28177.6-65.4171.6-174.3167.20113.4G283 R284 R285G283-K287 VanDerWaalsContact O-CD 3.3Å; G283-K287 WeakPolarHBondContact O-CD 3.3Å; G283-K287 WeakPolarHBondContact O-CE 3.43Å; G283-K287 WeakPolarHBondContact O-CG 3.43Å; R284-K287 WeakPolarHBondContact O-CA 3.25Å; R284-K287 WeakPolarHBondContact O-CB 3.41Å; R284-K287 PolarHBondContact O-N 2.87Å; R285-K287 PolarHBondContact O-N 3.13Å
288E67Low71Confident138 Ų13899.7 Ų99.765%0.64547%0.467SS*.Hα-helixtrans-85-36.1-175.9-71.4166-170.800111.7R284 R285 H290R284-E288 WeakPolarHBondContact O-CG 3.22Å; R284-E288 PolarHBondContact O-N 3.44Å; R285-E288 PolarHBondContact O-N 2.94Å; E288-H290 VanDerWaalsContact C-N 3.32Å; E288-H290 PolarHBondContact O-N 2.88Å
289E61.5Low70.9Confident101 Ų101101 Ų10147%0.47247%0.472SS..  trans-8568.6-178.1-67.1175.5127.300111.7R285 E291 M292R285-E289 PolarHBondContact O-N 3.39Å; E289-E291 PolarHBondContact O-N 2.99Å; E289-M292 HydrophobicContact CB-CE 3.78Å; E289-M292 HydrophobicContact CB-CG 4.02Å; E289-M292 HydrophobicContact CB-SD 4.17Å; E289-M292 PolarHBondContact O-N 3.37Å
290H55.4Low70.5Confident180 Ų180101.9 Ų101.983%0.83348%0.475SS*.THydrogen-bonded Turntrans-690.9-175.6-150.670.5000115.3E288E288-H290 VanDerWaalsContact C-N 3.32Å; E288-H290 PolarHBondContact O-N 2.88Å
291E56.1Low70.4Confident196 Ų196100.7 Ų100.792%0.91647%0.47SS*.THydrogen-bonded Turntrans-116.37.2-177.3-60-171.914500113.4E289E289-E291 PolarHBondContact O-N 2.99Å
292M57.7Low70.4Confident48 Ų48103.1 Ų103.124%0.23648%0.482CS..  trans-66.6146.1177.9-83.8-171.5-5800113.6E289 E296 L300E289-M292 HydrophobicContact CB-CE 3.78Å; E289-M292 HydrophobicContact CB-CG 4.02Å; E289-M292 HydrophobicContact CB-SD 4.17Å; E289-M292 PolarHBondContact O-N 3.37Å; M292-E296 HydrophobicContact SD-CB 4.31Å; M292-L300 HydrophobicContact CE-CD1 3.66Å; M292-L300 HydrophobicContact SD-CD1 3.66Å
293D64Low70.4Confident107 Ų107106.2 Ų106.257%0.57250%0.496SS*.  trans-68.6148.2172-152.5-10.7000110.7N295 E296 K297D293-N295 PolarHBondContact O-N 2.84Å; D293-N295 VanDerWaalsContact O-N 3.13Å; D293-E296 PolarHBondContact O-N 2.93Å; D293-K297 PolarHBondContact O-N 2.75Å
294I68.9Low70.7Confident120 Ų120106.2 Ų106.262%0.61549%0.492SS*.Hα-helixtrans-58-38.5-169.1-63.3174.8000111.3E296 K297 E298I294-E296 VanDerWaalsContact C-N 3.25Å; I294-E296 PolarHBondContact O-N 3.15Å; I294-K297 PolarHBondContact O-N 2.86Å; I294-E298 HydrophobicContact CG2-CG 4.45Å; I294-E298 PolarHBondContact O-N 2.92Å
295N70.8Confident71Confident102 Ų102109.9 Ų109.955%0.54551%0.506SS..Hα-helixtrans-66.6-18.8178.8-65.7-46.1000114.5D293 K299D293-N295 PolarHBondContact O-N 2.84Å; D293-N295 VanDerWaalsContact O-N 3.13Å; N295-K299 VanDerWaalsContact O-CD 3.29Å; N295-K299 WeakPolarHBondContact O-CD 3.44Å; N295-K299 WeakPolarHBondContact O-CE 3.32Å; N295-K299 VanDerWaalsContact O-CG 3.27Å; N295-K299 WeakPolarHBondContact O-CG 3.4Å
296E67.4Low71.4Confident105 Ų105109 Ų10949%0.49151%0.506SS..Hα-helixtrans-90.6-38176.4-59.4-163.213000110.5M292 D293 I294 K299 L300M292-E296 HydrophobicContact SD-CB 4.31Å; D293-E296 PolarHBondContact O-N 2.93Å; I294-E296 VanDerWaalsContact C-N 3.25Å; I294-E296 PolarHBondContact O-N 3.15Å; E296-K299 PolarHBondContact O-N 2.88Å; E296-L300 PolarHBondContact O-N 2.87Å
297K67.7Low71.9Confident93 Ų93110.6 Ų110.640%0.40451%0.509SS..Hα-helixtrans-59.5-46.5171.2-167.8176.4179.9-72.50112.3L286 D293 I294 K299 L300 E301L286-K297 HydrophobicContact CD1-CG 3.71Å; D293-K297 PolarHBondContact O-N 2.75Å; I294-K297 PolarHBondContact O-N 2.86Å; K297-K299 PolarHBondContact O-N 3.48Å; K297-L300 PolarHBondContact O-N 3.25Å; K297-E301 IonicContact NZ-OE1 2.65Å; K297-E301 PolarHBondContact NZ-OE1 3.41Å; K297-E301 PolarHBondContact O-N 2.88Å
298E77.4Confident72.5Confident118 Ų118107.6 Ų107.655%0.55150%0.498SS*.Hα-helixtrans-62.3-39.2177.5-74.4-172.8160.800112.6I294 E301 E302I294-E298 HydrophobicContact CG2-CG 4.45Å; I294-E298 PolarHBondContact O-N 2.92Å; E298-E301 PolarHBondContact O-N 2.89Å; E298-E302 WeakPolarHBondContact O-CB 3.39Å; E298-E302 PolarHBondContact O-N 3.26Å
299K79.8Confident73.4Confident130 Ų130106.5 Ų106.557%0.56550%0.496SS*.Hα-helixtrans-63.7-44175.3-72.5168.5-168.4163.30112.1N295 E296 K297 E301 E302 E303N295-K299 VanDerWaalsContact O-CD 3.29Å; N295-K299 WeakPolarHBondContact O-CD 3.44Å; N295-K299 WeakPolarHBondContact O-CE 3.32Å; N295-K299 VanDerWaalsContact O-CG 3.27Å; N295-K299 WeakPolarHBondContact O-CG 3.4Å; E296-K299 PolarHBondContact O-N 2.88Å; K297-K299 PolarHBondContact O-N 3.48Å; K299-E301 VanDerWaalsContact C-N 3.34Å; K299-E302 PolarHBondContact O-N 3.44Å; K299-E303 WeakPolarHBondContact O-CB 3.46Å; K299-E303 PolarHBondContact O-N 2.86Å
300L73.7Confident74.4Confident33 Ų33105.8 Ų105.817%0.17349%0.493CS..Hα-helixtrans-65.6-37.9177.7-73.2170.4000111.6L286 M292 E296 K297 E303 I304L286-L300 HydrophobicContact CD1-CB 3.99Å; M292-L300 HydrophobicContact CE-CD1 3.66Å; M292-L300 HydrophobicContact SD-CD1 3.66Å; E296-L300 PolarHBondContact O-N 2.87Å; K297-L300 PolarHBondContact O-N 3.25Å; L300-E303 PolarHBondContact O-N 3.29Å; L300-I304 WeakPolarHBondContact O-CB 3.43Å; L300-I304 WeakPolarHBondContact O-CD1 3.5Å; L300-I304 VanDerWaalsContact O-CG1 3.22Å; L300-I304 WeakPolarHBondContact O-CG1 3.39Å; L300-I304 PolarHBondContact O-N 3.43Å
301E78.1Confident75.8Confident80 Ų8097.8 Ų97.837%0.37446%0.456SS..Hα-helixtrans-65.3-40.5173.1-76.2177.4-170.600112.5L286 K297 E298 K299 R305L286-E301 HydrophobicContact CD1-CG 4.02Å; L286-E301 HydrophobicContact CD2-CG 3.61Å; L286-E301 HydrophobicContact CG-CG 4.45Å; K297-E301 IonicContact NZ-OE1 2.65Å; K297-E301 PolarHBondContact NZ-OE1 3.41Å; K297-E301 PolarHBondContact O-N 2.88Å; E298-E301 PolarHBondContact O-N 2.89Å; K299-E301 VanDerWaalsContact C-N 3.34Å; E301-R305 VanDerWaalsContact O-CB 3.23Å; E301-R305 WeakPolarHBondContact O-CB 3.33Å; E301-R305 PolarHBondContact O-N 3.16Å
302E82Confident77.2Confident138 Ų13891.1 Ų91.165%0.64543%0.434SS*.Hα-helixtrans-68.3-39174.9-170.5167.5-129.500112.3E298 K299 R305 K306E298-E302 WeakPolarHBondContact O-CB 3.39Å; E298-E302 PolarHBondContact O-N 3.26Å; K299-E302 PolarHBondContact O-N 3.44Å; E302-R305 PolarHBondContact O-N 2.89Å; E302-K306 WeakPolarHBondContact O-CB 3.48Å; E302-K306 PolarHBondContact O-N 3.43Å
303E80.3Confident78.5Confident87 Ų8791.9 Ų91.941%0.40744%0.444SS..Hα-helixtrans-70.9-34.1177.7-144-164.8141.600112.6K299 L300 R307K299-E303 WeakPolarHBondContact O-CB 3.46Å; K299-E303 PolarHBondContact O-N 2.86Å; L300-E303 PolarHBondContact O-N 3.29Å; E303-R307 PolarHBondContact O-N 2.68Å; E303-R307 IonicContact OE1-CZ 3.82Å; E303-R307 IonicContact OE1-NH1 3.31Å; E303-R307 PolarHBondContact OE1-NH1 3.43Å; E303-R307 IonicContact OE1-NH2 3.08Å; E303-R307 PolarHBondContact OE1-NH2 2.73Å
304I81.8Confident79.4Confident17 Ų1788.2 Ų88.29%0.08743%0.426CS..Hα-helixtrans-64.5-54.8169-75.4163.7000109.7V279 L282 L286 L300 K306 R307 E308V279-I304 HydrophobicContact CG1-CG2 4.26Å; L282-I304 HydrophobicContact CB-CD1 4.01Å; L282-I304 HydrophobicContact CB-CG1 3.75Å; L286-I304 HydrophobicContact CB-CD1 4.43Å; L286-I304 HydrophobicContact CD2-CD1 3.88Å; L300-I304 WeakPolarHBondContact O-CB 3.43Å; L300-I304 WeakPolarHBondContact O-CD1 3.5Å; L300-I304 VanDerWaalsContact O-CG1 3.22Å; L300-I304 WeakPolarHBondContact O-CG1 3.39Å; L300-I304 PolarHBondContact O-N 3.43Å; I304-K306 PolarHBondContact O-N 3.13Å; I304-R307 CarbonylContact O-C 3.59Å; I304-R307 PolarHBondContact O-N 2.95Å; I304-E308 HydrophobicContact CG2-CG 4.21Å; I304-E308 WeakPolarHBondContact O-CG 3.46Å; I304-E308 PolarHBondContact O-N 3.45Å
305R84.1Confident80.2Confident166 Ų16688.6 Ų88.663%0.62642%0.419SS*.Hα-helixtrans-56.2-36.6-179.6-179.2-178.2174.2-152.3-2.2112.2E301 E302 L309E301-R305 VanDerWaalsContact O-CB 3.23Å; E301-R305 WeakPolarHBondContact O-CB 3.33Å; E301-R305 PolarHBondContact O-N 3.16Å; E302-R305 PolarHBondContact O-N 2.89Å; R305-L309 WeakPolarHBondContact O-CG 3.42Å; R305-L309 PolarHBondContact O-N 2.84Å
306K85.2Confident80.9Confident126 Ų12689.5 Ų89.555%0.54842%0.42SS..Hα-helixtrans-65.3-49174.1-169.2-171.9177.8-136.90111.8E302 I304 E308 L309 E310E302-K306 WeakPolarHBondContact O-CB 3.48Å; E302-K306 PolarHBondContact O-N 3.43Å; I304-K306 PolarHBondContact O-N 3.13Å; K306-E308 VanDerWaalsContact C-N 3.32Å; K306-E308 PolarHBondContact O-N 2.9Å; K306-L309 PolarHBondContact O-N 2.85Å; K306-E310 WeakPolarHBondContact CE-OE1 3.34Å; K306-E310 IonicContact NZ-OE1 2.66Å; K306-E310 PolarHBondContact NZ-OE1 3.5Å; K306-E310 VanDerWaalsContact NZ-OE1 3.08Å; K306-E310 WeakPolarHBondContact O-CG 3.47Å; K306-E310 PolarHBondContact O-N 3.17Å
307R81.8Confident81.7Confident69 Ų6990.1 Ų90.126%0.2642%0.423SS..Hα-helixtrans-64.6-33.6176.8-74.4-168.9-177.477.92.9112.8V279 L282 E303 I304 L309 E310 I311V279-R307 HydrophobicContact CG2-CB 3.41Å; V279-R307 VanDerWaalsContact CG2-CB 3.41Å; V279-R307 HydrophobicContact CG2-CG 4.3Å; L282-R307 VanDerWaalsContact CD1-NH1 3.3Å; E303-R307 PolarHBondContact O-N 2.68Å; E303-R307 IonicContact OE1-CZ 3.82Å; E303-R307 IonicContact OE1-NH1 3.31Å; E303-R307 PolarHBondContact OE1-NH1 3.43Å; E303-R307 IonicContact OE1-NH2 3.08Å; E303-R307 PolarHBondContact OE1-NH2 2.73Å; I304-R307 CarbonylContact O-C 3.59Å; I304-R307 PolarHBondContact O-N 2.95Å; R307-L309 VanDerWaalsContact C-N 3.35Å; R307-E310 PolarHBondContact O-N 3.33Å; R307-I311 WeakPolarHBondContact O-CB 3.46Å; R307-I311 VanDerWaalsContact O-CG1 3.27Å; R307-I311 WeakPolarHBondContact O-CG1 3.42Å; R307-I311 PolarHBondContact O-N 3.26Å
308E82Confident82.5Confident105 Ų10586.4 Ų86.449%0.49141%0.408SS..Hα-helixtrans-62.8-39.5173.7-72.9-178.2151.200112.2V279 I304 K306 I311 A312V279-E308 HydrophobicContact CG1-CG 4.05Å; I304-E308 HydrophobicContact CG2-CG 4.21Å; I304-E308 WeakPolarHBondContact O-CG 3.46Å; I304-E308 PolarHBondContact O-N 3.45Å; K306-E308 VanDerWaalsContact C-N 3.32Å; K306-E308 PolarHBondContact O-N 2.9Å; E308-I311 PolarHBondContact O-N 3.01Å; E308-A312 WeakPolarHBondContact O-CB 3.23Å; E308-A312 PolarHBondContact O-N 3.22Å
309L85.4Confident82.8Confident115 Ų11584.4 Ų84.460%0.60241%0.407SS*.Hα-helixtrans-67.6-40.8173.7-71.2166.9000112.1R305 K306 R307 A312 S313R305-L309 WeakPolarHBondContact O-CG 3.42Å; R305-L309 PolarHBondContact O-N 2.84Å; K306-L309 PolarHBondContact O-N 2.85Å; R307-L309 VanDerWaalsContact C-N 3.35Å; L309-A312 PolarHBondContact O-N 3.26Å; L309-S313 PolarHBondContact O-N 2.9Å; L309-S313 VanDerWaalsContact O-N 3.12Å
310E82.2Confident83Confident87 Ų8783 Ų8341%0.40740%0.402SS..Hα-helixtrans-63.1-42.6174.3-68.9171.2-171.900111K306 R307 S313 V314K306-E310 WeakPolarHBondContact CE-OE1 3.34Å; K306-E310 IonicContact NZ-OE1 2.66Å; K306-E310 PolarHBondContact NZ-OE1 3.5Å; K306-E310 VanDerWaalsContact NZ-OE1 3.08Å; K306-E310 WeakPolarHBondContact O-CG 3.47Å; K306-E310 PolarHBondContact O-N 3.17Å; R307-E310 PolarHBondContact O-N 3.33Å; E310-S313 PolarHBondContact O-N 2.83Å; E310-V314 WeakPolarHBondContact O-CG2 3.43Å; E310-V314 PolarHBondContact O-N 2.83Å; E310-V314 VanDerWaalsContact O-N 3.08Å
311I85Confident83.4Confident12 Ų1285.3 Ų85.36%0.06241%0.411CS..Hα-helixtrans-61.4-41.7172.7-76.4166.7000111.7L272 R275 E276 V279 R307 E308 S313 V314 R315L272-I311 HydrophobicContact CD1-CG2 4.08Å; R275-I311 HydrophobicContact CB-CD1 4.11Å; R275-I311 HydrophobicContact CB-CG1 3.89Å; E276-I311 HydrophobicContact CG-CD1 4.11Å; E276-I311 HydrophobicContact CG-CG2 4.06Å; V279-I311 HydrophobicContact CB-CD1 4.14Å; V279-I311 HydrophobicContact CG2-CD1 3.57Å; R307-I311 WeakPolarHBondContact O-CB 3.46Å; R307-I311 VanDerWaalsContact O-CG1 3.27Å; R307-I311 WeakPolarHBondContact O-CG1 3.42Å; R307-I311 PolarHBondContact O-N 3.26Å; E308-I311 PolarHBondContact O-N 3.01Å; I311-S313 VanDerWaalsContact C-N 3.34Å; I311-S313 PolarHBondContact O-N 3.48Å; I311-V314 PolarHBondContact O-N 3.06Å; I311-R315 HydrophobicContact CG2-CG 4.36Å; I311-R315 WeakPolarHBondContact O-CB 3.39Å; I311-R315 VanDerWaalsContact O-CG 3.3Å; I311-R315 WeakPolarHBondContact O-CG 3.41Å; I311-R315 PolarHBondContact O-N 3.33Å
312A85.2Confident83.6Confident55 Ų5583.1 Ų83.146%0.45540%0.402SS..Hα-helixtrans-62-40.3177.600000112.2E308 L309 Q316E308-A312 WeakPolarHBondContact O-CB 3.23Å; E308-A312 PolarHBondContact O-N 3.22Å; L309-A312 PolarHBondContact O-N 3.26Å; A312-Q316 PolarHBondContact O-N 3.09Å
313S85.3Confident83.7Confident64 Ų6478.9 Ų78.945%0.44839%0.391SS..Hα-helixtrans-63.8-49.3174.4-162.30000111.6L309 E310 I311 R315 Q316 E317L309-S313 PolarHBondContact O-N 2.9Å; L309-S313 VanDerWaalsContact O-N 3.12Å; E310-S313 PolarHBondContact O-N 2.83Å; I311-S313 VanDerWaalsContact C-N 3.34Å; I311-S313 PolarHBondContact O-N 3.48Å; S313-R315 VanDerWaalsContact C-N 3.29Å; S313-R315 PolarHBondContact O-N 2.95Å; S313-Q316 WeakPolarHBondContact O-CB 3.15Å; S313-Q316 PolarHBondContact O-N 3.49Å; S313-E317 PolarHBondContact O-N 2.8Å; S313-E317 VanDerWaalsContact O-N 3.07Å
314V83.7Confident83.8Confident30 Ų3080.4 Ų80.418%0.18240%0.398CS..Hα-helixtrans-64.2-33.9179.9175.30000111.7L272 E310 I311 E317 I318L272-V314 HydrophobicContact CB-CG1 4.45Å; L272-V314 HydrophobicContact CD1-CB 4.45Å; L272-V314 HydrophobicContact CD1-CG1 4.13Å; E310-V314 WeakPolarHBondContact O-CG2 3.43Å; E310-V314 PolarHBondContact O-N 2.83Å; E310-V314 VanDerWaalsContact O-N 3.08Å; I311-V314 PolarHBondContact O-N 3.06Å; V314-E317 PolarHBondContact O-N 2.91Å; V314-I318 HydrophobicContact CG1-CD1 3.81Å; V314-I318 HydrophobicContact CG1-CG1 4.45Å; V314-I318 WeakPolarHBondContact O-CB 3.25Å; V314-I318 WeakPolarHBondContact O-CG1 3.33Å; V314-I318 PolarHBondContact O-N 2.7Å
315R84.7Confident83.8Confident128 Ų12880 Ų8048%0.48340%0.396SS..Hα-helixtrans-62.5-38.6171.6-80173.4170.3-167.6-5.7112.6L272 E276 I311 S313 S319L272-R315 HydrophobicContact CD1-CG 3.86Å; L272-R315 HydrophobicContact CD2-CG 3.71Å; L272-R315 HydrophobicContact CG-CG 4.43Å; E276-R315 IonicContact OE1-CZ 3.18Å; E276-R315 IonicContact OE1-NE 3.95Å; E276-R315 PolarHBondContact OE1-NE 2.88Å; E276-R315 IonicContact OE1-NH2 3.57Å; E276-R315 PolarHBondContact OE1-NH2 3.28Å; E276-R315 IonicContact OE2-CZ 2.68Å; E276-R315 IonicContact OE2-NH2 3.38Å; E276-R315 PolarHBondContact OE2-NH2 3.45Å; I311-R315 HydrophobicContact CG2-CG 4.36Å; I311-R315 WeakPolarHBondContact O-CB 3.39Å; I311-R315 VanDerWaalsContact O-CG 3.3Å; I311-R315 WeakPolarHBondContact O-CG 3.41Å; I311-R315 PolarHBondContact O-N 3.33Å; S313-R315 VanDerWaalsContact C-N 3.29Å; S313-R315 PolarHBondContact O-N 2.95Å; R315-S319 WeakPolarHBondContact O-CB 3.49Å; R315-S319 PolarHBondContact O-N 2.98Å
316Q86Confident83.8Confident122 Ų12278.9 Ų78.957%0.5739%0.392SS*.Hα-helixtrans-66.7-48174.9-175-179.3-3200111A312 S313 I318 S319 E320A312-Q316 PolarHBondContact O-N 3.09Å; S313-Q316 WeakPolarHBondContact O-CB 3.15Å; S313-Q316 PolarHBondContact O-N 3.49Å; Q316-I318 VanDerWaalsContact C-N 3.3Å; Q316-I318 PolarHBondContact O-N 2.67Å; Q316-S319 WeakPolarHBondContact O-CA 3.36Å; Q316-S319 WeakPolarHBondContact O-CB 3.46Å; Q316-S319 PolarHBondContact O-N 3.4Å; Q316-E320 WeakPolarHBondContact CG-OE1 3.27Å; Q316-E320 PolarHBondContact NE2-OE1 3.19Å; Q316-E320 PolarHBondContact O-N 2.86Å
317E84.1Confident83.7Confident117 Ų11781 Ų8155%0.54740%0.396SS..Hα-helixtrans-58.3-41177.8-70.4177.6-153.100112.3S313 V314 E320 K321S313-E317 PolarHBondContact O-N 2.8Å; S313-E317 VanDerWaalsContact O-N 3.07Å; V314-E317 PolarHBondContact O-N 2.91Å; E317-E320 PolarHBondContact O-N 2.89Å; E317-K321 PolarHBondContact O-N 3.32Å
318I85.1Confident83.6Confident15 Ų1580.1 Ų80.18%0.07740%0.396CS..Hα-helixtrans-64.7-43.6173.9-70.9166.6000110.3A268 Q269 L272 V314 Q316 E320 K321 D322A268-I318 HydrophobicContact CB-CD1 4.09Å; A268-I318 HydrophobicContact CB-CG1 3.93Å; A268-I318 WeakPolarHBondContact O-CD1 3.41Å; Q269-I318 HydrophobicContact CG-CG2 3.93Å; L272-I318 HydrophobicContact CB-CD1 3.67Å; L272-I318 HydrophobicContact CD2-CD1 3.75Å; L272-I318 HydrophobicContact CG-CD1 4.22Å; V314-I318 HydrophobicContact CG1-CD1 3.81Å; V314-I318 HydrophobicContact CG1-CG1 4.45Å; V314-I318 WeakPolarHBondContact O-CB 3.25Å; V314-I318 WeakPolarHBondContact O-CG1 3.33Å; V314-I318 PolarHBondContact O-N 2.7Å; Q316-I318 VanDerWaalsContact C-N 3.3Å; Q316-I318 PolarHBondContact O-N 2.67Å; I318-E320 VanDerWaalsContact C-N 3.29Å; I318-E320 PolarHBondContact O-N 3.23Å; I318-K321 CarbonylContact O-C 3.58Å; I318-K321 PolarHBondContact O-N 3.12Å; I318-D322 WeakPolarHBondContact O-CB 3.44Å; I318-D322 PolarHBondContact O-N 3.3Å
319S84.2Confident83.4Confident77 Ų7779 Ų7954%0.53839%0.391SS..Hα-helixtrans-60.6-36.8176.8-1690000112.9R315 Q316 D322 A323R315-S319 WeakPolarHBondContact O-CB 3.49Å; R315-S319 PolarHBondContact O-N 2.98Å; Q316-S319 WeakPolarHBondContact O-CA 3.36Å; Q316-S319 WeakPolarHBondContact O-CB 3.46Å; Q316-S319 PolarHBondContact O-N 3.4Å; S319-D322 WeakPolarHBondContact O-CB 3.45Å; S319-D322 PolarHBondContact O-N 3.09Å; S319-A323 PolarHBondContact O-N 2.78Å; S319-A323 VanDerWaalsContact O-N 3.09Å
320E84.1Confident83.4Confident100 Ų10079.9 Ų79.947%0.46739%0.392SS..Hα-helixtrans-71-40.7175.2-69.7179.7-15400111.9Q316 E317 I318 A323 Q324Q316-E320 WeakPolarHBondContact CG-OE1 3.27Å; Q316-E320 PolarHBondContact NE2-OE1 3.19Å; Q316-E320 PolarHBondContact O-N 2.86Å; E317-E320 PolarHBondContact O-N 2.89Å; I318-E320 VanDerWaalsContact C-N 3.29Å; I318-E320 PolarHBondContact O-N 3.23Å; E320-A323 PolarHBondContact O-N 3.47Å; E320-Q324 WeakPolarHBondContact O-CG 3.34Å; E320-Q324 PolarHBondContact O-N 3.01Å
321K81.7Confident83.2Confident82 Ų8281.4 Ų81.436%0.35740%0.399SS..Hα-helixtrans-64.8-35.7171-74.9-164.9172.6-160.80112.6E264 L265 E317 I318 Q324 T325E264-K321 IonicContact OE2-NZ 2.72Å; E264-K321 PolarHBondContact OE2-NZ 3.39Å; L265-K321 HydrophobicContact CD1-CB 4.13Å; E317-K321 PolarHBondContact O-N 3.32Å; I318-K321 CarbonylContact O-C 3.58Å; I318-K321 PolarHBondContact O-N 3.12Å; K321-Q324 PolarHBondContact O-N 3.34Å; K321-T325 VanDerWaalsContact O-CB 3.32Å; K321-T325 WeakPolarHBondContact O-CB 3.37Å; K321-T325 PolarHBondContact O-N 2.64Å; K321-T325 PolarHBondContact O-OG1 2.95Å
322D80.8Confident83Confident33 Ų3381.2 Ų81.218%0.17640%0.399CS..Hα-helixtrans-60.6-46173.9-121.3-75.4000110.7L265 Q269 I318 S319 T325 R326L265-D322 HydrophobicContact CD1-CB 4.18Å; Q269-D322 PolarHBondContact NE2-OD2 2.93Å; I318-D322 WeakPolarHBondContact O-CB 3.44Å; I318-D322 PolarHBondContact O-N 3.3Å; S319-D322 WeakPolarHBondContact O-CB 3.45Å; S319-D322 PolarHBondContact O-N 3.09Å; D322-T325 PolarHBondContact O-N 2.9Å; D322-R326 WeakPolarHBondContact O-CG 3.45Å; D322-R326 PolarHBondContact O-N 2.86Å; D322-R326 IonicContact OD1-CZ 3.14Å; D322-R326 IonicContact OD1-NE 2.6Å; D322-R326 PolarHBondContact OD1-NE 2.86Å; D322-R326 IonicContact OD1-NH2 3.07Å; D322-R326 PolarHBondContact OD1-NH2 3.11Å
323A85.3Confident82.8Confident50 Ų5085.7 Ų85.741%0.41341%0.41SS..Hα-helixtrans-65.6-37.5177.300000112.9S319 E320S319-A323 PolarHBondContact O-N 2.78Å; S319-A323 VanDerWaalsContact O-N 3.09Å; E320-A323 PolarHBondContact O-N 3.47Å
324Q82.5Confident82.5Confident119 Ų11987 Ų8756%0.55641%0.409SS*.Hα-helixtrans-68.2-42.6173.4-68.7175.624.500111.7E320 K321 R326 R327 L328E320-Q324 WeakPolarHBondContact O-CG 3.34Å; E320-Q324 PolarHBondContact O-N 3.01Å; K321-Q324 PolarHBondContact O-N 3.34Å; Q324-R326 VanDerWaalsContact C-N 3.32Å; Q324-R326 PolarHBondContact O-N 2.88Å; Q324-R327 PolarHBondContact O-N 2.85Å; Q324-L328 PolarHBondContact O-N 3.08Å; Q324-L328 VanDerWaalsContact O-N 3.14Å
325T82.1Confident82.2Confident9 Ų986 Ų866%0.05541%0.405CS..Hα-helixtrans-64.9-35-179-57.10000112L262 K321 D322 L328 Q329L262-T325 HydrophobicContact CD2-CG2 3.54Å; L262-T325 HydrophobicContact CG-CG2 3.93Å; K321-T325 VanDerWaalsContact O-CB 3.32Å; K321-T325 WeakPolarHBondContact O-CB 3.37Å; K321-T325 PolarHBondContact O-N 2.64Å; K321-T325 PolarHBondContact O-OG1 2.95Å; D322-T325 PolarHBondContact O-N 2.9Å; T325-L328 PolarHBondContact O-N 2.99Å; T325-Q329 WeakPolarHBondContact O-CG 3.2Å; T325-Q329 PolarHBondContact O-N 3.41Å
326R83Confident81.9Confident142 Ų14286.2 Ų86.254%0.53641%0.405SS..Hα-helixtrans-64.9-39.1173.7-70.6172.5-151.8-158.23.9113.3D322 Q324 L328 Q329 E330D322-R326 WeakPolarHBondContact O-CG 3.45Å; D322-R326 PolarHBondContact O-N 2.86Å; D322-R326 IonicContact OD1-CZ 3.14Å; D322-R326 IonicContact OD1-NE 2.6Å; D322-R326 PolarHBondContact OD1-NE 2.86Å; D322-R326 IonicContact OD1-NH2 3.07Å; D322-R326 PolarHBondContact OD1-NH2 3.11Å; Q324-R326 VanDerWaalsContact C-N 3.32Å; Q324-R326 PolarHBondContact O-N 2.88Å; R326-L328 VanDerWaalsContact C-N 3.33Å; R326-L328 PolarHBondContact O-N 3.4Å; R326-Q329 WeakPolarHBondContact O-CB 3.02Å; R326-Q329 PolarHBondContact O-N 3.1Å; R326-Q329 VanDerWaalsContact O-N 3.13Å; R326-E330 PolarHBondContact O-N 2.96Å
327R82.9Confident81.6Confident170 Ų17086.5 Ų86.564%0.64240%0.401SS*.Hα-helixtrans-63.9-40.3173.8-66.4178.1-177177.92111.5Q324 Q329 E330 E331Q324-R327 PolarHBondContact O-N 2.85Å; R327-Q329 VanDerWaalsContact C-N 3.29Å; R327-Q329 PolarHBondContact O-N 3.01Å; R327-E330 PolarHBondContact O-N 3.24Å; R327-E331 PolarHBondContact O-N 3.02Å
328L79.8Confident81.2Confident50 Ų5087.2 Ų87.226%0.26240%0.399SS..Hα-helixtrans-65-32173.3-66.4172.1000112.2L258 Q324 T325 R326 V332L258-L328 HydrophobicContact CD1-CB 4.03Å; L258-L328 VanDerWaalsContact CD1-O 3.3Å; L258-L328 WeakPolarHBondContact CD1-O 3.18Å; Q324-L328 PolarHBondContact O-N 3.08Å; Q324-L328 VanDerWaalsContact O-N 3.14Å; T325-L328 PolarHBondContact O-N 2.99Å; R326-L328 VanDerWaalsContact C-N 3.33Å; R326-L328 PolarHBondContact O-N 3.4Å; L328-V332 WeakPolarHBondContact O-CB 3.39Å; L328-V332 WeakPolarHBondContact O-CG2 3.35Å; L328-V332 PolarHBondContact O-N 2.9Å
329Q79.2Confident80.6Confident82 Ų8288.9 Ų88.938%0.38341%0.406SS..Hα-helixtrans-63.7-47.1172.8-74.6169.4-27.400111.2L258 T325 R326 R327 E331 V332 E333L258-Q329 VanDerWaalsContact CD1-CA 3.43Å; L258-Q329 HydrophobicContact CD1-CB 4.12Å; L258-Q329 HydrophobicContact CD1-CG 3.59Å; T325-Q329 WeakPolarHBondContact O-CG 3.2Å; T325-Q329 PolarHBondContact O-N 3.41Å; R326-Q329 WeakPolarHBondContact O-CB 3.02Å; R326-Q329 PolarHBondContact O-N 3.1Å; R326-Q329 VanDerWaalsContact O-N 3.13Å; R327-Q329 VanDerWaalsContact C-N 3.29Å; R327-Q329 PolarHBondContact O-N 3.01Å; Q329-E331 PolarHBondContact O-N 2.91Å; Q329-V332 PolarHBondContact O-N 2.67Å; Q329-V332 VanDerWaalsContact O-N 3.17Å; Q329-E333 PolarHBondContact O-N 3.34Å
330E83.6Confident80.2Confident134 Ų13491.7 Ų91.763%0.62641%0.411SS*.Hα-helixtrans-58.8-46.4175.2-66.6166.3177.400111.5R326 R327 V332 E333 E334R326-E330 PolarHBondContact O-N 2.96Å; R327-E330 PolarHBondContact O-N 3.24Å; E330-V332 VanDerWaalsContact C-N 3.3Å; E330-V332 PolarHBondContact O-N 2.7Å; E330-E333 PolarHBondContact O-N 2.9Å; E330-E334 PolarHBondContact O-N 3.45Å
331E79.4Confident79.8Confident118 Ų11891.7 Ų91.755%0.55141%0.411SS*.Hα-helixtrans-61.1-35175-73-178.9-169.100113.1R327 Q329 A335R327-E331 PolarHBondContact O-N 3.02Å; Q329-E331 PolarHBondContact O-N 2.91Å; E331-A335 WeakPolarHBondContact O-CB 3.34Å; E331-A335 PolarHBondContact O-N 3.29Å
332V80Confident79.3Confident9 Ų988.3 Ų88.36%0.05540%0.399CS..Hα-helixtrans-79.4-32.1179.5164.20000113I255 L258 L328 Q329 E330 E334 A335 R336I255-V332 HydrophobicContact CG1-CG1 3.86Å; L258-V332 HydrophobicContact CB-CG2 3.76Å; L258-V332 HydrophobicContact CD1-CB 4.07Å; L258-V332 HydrophobicContact CD1-CG2 3.96Å; L258-V332 HydrophobicContact CD2-CG1 4.27Å; L258-V332 HydrophobicContact CD2-CG2 4.42Å; L258-V332 HydrophobicContact CG-CG2 4.27Å; L328-V332 WeakPolarHBondContact O-CB 3.39Å; L328-V332 WeakPolarHBondContact O-CG2 3.35Å; L328-V332 PolarHBondContact O-N 2.9Å; Q329-V332 PolarHBondContact O-N 2.67Å; Q329-V332 VanDerWaalsContact O-N 3.17Å; E330-V332 VanDerWaalsContact C-N 3.3Å; E330-V332 PolarHBondContact O-N 2.7Å; V332-E334 VanDerWaalsContact C-N 3.34Å; V332-A335 PolarHBondContact O-N 2.92Å; V332-R336 HydrophobicContact CG1-CG 4.39Å; V332-R336 WeakPolarHBondContact O-CB 3.43Å; V332-R336 WeakPolarHBondContact O-CG 3.44Å; V332-R336 PolarHBondContact O-N 3.44Å
333E81.1Confident78.8Confident149 Ų14990.5 Ų90.570%0.69642%0.416SS*.Hα-helixtrans-64.3-40.8170.9-72.2-167.5168.600111Q329 E330 R336 R337Q329-E333 PolarHBondContact O-N 3.34Å; E330-E333 PolarHBondContact O-N 2.9Å; E333-R336 PolarHBondContact O-N 3.05Å; E333-R337 PolarHBondContact O-N 2.88Å; E333-R337 VanDerWaalsContact O-N 3.09Å
334E80.2Confident78.2Confident91 Ų9193.5 Ų93.543%0.42542%0.422SS..Hα-helixtrans-62.1-45.8169.6-74.8-145.4168.400112.7E330 V332 R336 R337 R338E330-E334 PolarHBondContact O-N 3.45Å; V332-E334 VanDerWaalsContact C-N 3.34Å; E334-R336 VanDerWaalsContact C-N 3.3Å; E334-R336 PolarHBondContact O-N 3.15Å; E334-R337 PolarHBondContact O-N 2.96Å; E334-R338 WeakPolarHBondContact O-CG 3.22Å; E334-R338 PolarHBondContact O-N 3.01Å; E334-R338 IonicContact OE2-CZ 2.63Å; E334-R338 IonicContact OE2-NE 2.92Å; E334-R338 IonicContact OE2-NH2 2.7Å; E334-R338 PolarHBondContact OE2-NH2 3.02Å
335A77.6Confident77.5Confident10 Ų1090.5 Ų90.58%0.08342%0.418CS..Hα-helixtrans-60.9-38.5179.200000112.3A251 E331 V332 Q339A251-A335 HydrophobicContact CB-CB 4.06Å; E331-A335 WeakPolarHBondContact O-CB 3.34Å; E331-A335 PolarHBondContact O-N 3.29Å; V332-A335 PolarHBondContact O-N 2.92Å; A335-Q339 WeakPolarHBondContact O-CB 3.45Å; A335-Q339 PolarHBondContact O-N 2.91Å
336R77.3Confident76.8Confident131 Ų13194.1 Ų94.149%0.49444%0.436SS..Hα-helixtrans-66.8-37.7175-78.1-178.9173.2-153.1-1.2112.6I255 V332 E333 E334 Q339 Q340I255-R336 HydrophobicContact CD1-CG 3.97Å; I255-R336 HydrophobicContact CG1-CG 4.35Å; V332-R336 HydrophobicContact CG1-CG 4.39Å; V332-R336 WeakPolarHBondContact O-CB 3.43Å; V332-R336 WeakPolarHBondContact O-CG 3.44Å; V332-R336 PolarHBondContact O-N 3.44Å; E333-R336 PolarHBondContact O-N 3.05Å; E334-R336 VanDerWaalsContact C-N 3.3Å; E334-R336 PolarHBondContact O-N 3.15Å; R336-Q339 WeakPolarHBondContact O-CB 3.48Å; R336-Q339 PolarHBondContact O-N 3.11Å; R336-Q340 PolarHBondContact O-N 3.3Å; R336-Q340 VanDerWaalsContact O-N 3.08Å
337R80.7Confident76.1Confident128 Ų12893.4 Ų93.448%0.48344%0.442SS..Hα-helixtrans-65-47.5175.4-151.6-169.474.9-128.3-5.7111.2E333 E334 Q339 Q340 E341E333-R337 PolarHBondContact O-N 2.88Å; E333-R337 VanDerWaalsContact O-N 3.09Å; E334-R337 PolarHBondContact O-N 2.96Å; R337-Q339 VanDerWaalsContact C-N 3.3Å; R337-Q339 PolarHBondContact O-N 2.97Å; R337-Q340 PolarHBondContact O-N 3.15Å; R337-Q340 VanDerWaalsContact O-N 3.09Å; R337-E341 IonicContact CZ-OE1 3.15Å; R337-E341 IonicContact NE-OE1 2.66Å; R337-E341 PolarHBondContact NE-OE1 3Å; R337-E341 IonicContact NH2-OE1 2.73Å; R337-E341 PolarHBondContact NH2-OE1 3.25Å; R337-E341 WeakPolarHBondContact O-CG 3.47Å; R337-E341 PolarHBondContact O-N 3.47Å
338R74.7Confident75.3Confident132 Ų13293.1 Ų93.150%0.49844%0.441SS..Hα-helixtrans-59.6-39.3174.8-62.9176.6-157.5-173.36.9111.9E334 Q340 E341 A342E334-R338 WeakPolarHBondContact O-CG 3.22Å; E334-R338 PolarHBondContact O-N 3.01Å; E334-R338 IonicContact OE2-CZ 2.63Å; E334-R338 IonicContact OE2-NE 2.92Å; E334-R338 IonicContact OE2-NH2 2.7Å; E334-R338 PolarHBondContact OE2-NH2 3.02Å; R338-Q340 PolarHBondContact O-N 3.48Å; R338-E341 PolarHBondContact O-N 3.03Å; R338-A342 VanDerWaalsContact O-CB 3.31Å; R338-A342 WeakPolarHBondContact O-CB 3.46Å; R338-A342 PolarHBondContact O-N 3.45Å
339Q72.6Confident74.3Confident51 Ų5192.9 Ų92.924%0.23845%0.446CS..Hα-helixtrans-60.6-39.1173.7165.1173.773.300113.1L248 A251 A335 R336 R337 S343L248-Q339 HydrophobicContact CD1-CB 4.47Å; L248-Q339 HydrophobicContact CD1-CG 3.79Å; L248-Q339 VanDerWaalsContact CD1-NE2 3.34Å; A251-Q339 HydrophobicContact CB-CB 4.46Å; A335-Q339 WeakPolarHBondContact O-CB 3.45Å; A335-Q339 PolarHBondContact O-N 2.91Å; R336-Q339 WeakPolarHBondContact O-CB 3.48Å; R336-Q339 PolarHBondContact O-N 3.11Å; R337-Q339 VanDerWaalsContact C-N 3.3Å; R337-Q339 PolarHBondContact O-N 2.97Å; Q339-S343 VanDerWaalsContact O-CB 3.3Å; Q339-S343 WeakPolarHBondContact O-CB 3.38Å; Q339-S343 PolarHBondContact O-N 3.41Å; Q339-S343 VanDerWaalsContact O-N 3.1Å
340Q76Confident73.2Confident135 Ų13594 Ų9463%0.63146%0.458SS*.Hα-helixtrans-69.2-46.9174.8-72.3-178.3-38.900111.6R336 R337 R338 A342 S343 E344R336-Q340 PolarHBondContact O-N 3.3Å; R336-Q340 VanDerWaalsContact O-N 3.08Å; R337-Q340 PolarHBondContact O-N 3.15Å; R337-Q340 VanDerWaalsContact O-N 3.09Å; R338-Q340 PolarHBondContact O-N 3.48Å; Q340-A342 VanDerWaalsContact C-N 3.33Å; Q340-A342 PolarHBondContact O-N 3.43Å; Q340-S343 PolarHBondContact O-N 3.47Å; Q340-S343 VanDerWaalsContact O-N 3.17Å; Q340-E344 PolarHBondContact O-N 3.44Å
341E76.2Confident71.7Confident100 Ų10093.1 Ų93.147%0.46746%0.463SS..Hα-helixtrans-55.5-46.2176.9-68164.2-162.900111.4R337 R338 A345R337-E341 IonicContact CZ-OE1 3.15Å; R337-E341 IonicContact NE-OE1 2.66Å; R337-E341 PolarHBondContact NE-OE1 3Å; R337-E341 IonicContact NH2-OE1 2.73Å; R337-E341 PolarHBondContact NH2-OE1 3.25Å; R337-E341 WeakPolarHBondContact O-CG 3.47Å; R337-E341 PolarHBondContact O-N 3.47Å; R338-E341 PolarHBondContact O-N 3.03Å; E341-A345 PolarHBondContact O-N 3.17Å
342A69.8Low69.9Low12 Ų1296 Ų9610%0.09948%0.476CS..Hα-helixtrans-66.1-38.1176.500000113.6A244 R338 Q340 A345 L346A244-A342 HydrophobicContact CB-CB 4.12Å; R338-A342 VanDerWaalsContact O-CB 3.31Å; R338-A342 WeakPolarHBondContact O-CB 3.46Å; R338-A342 PolarHBondContact O-N 3.45Å; Q340-A342 VanDerWaalsContact C-N 3.33Å; Q340-A342 PolarHBondContact O-N 3.43Å; A342-A345 PolarHBondContact O-N 3.39Å; A342-L346 PolarHBondContact O-N 3.02Å; A342-L346 VanDerWaalsContact O-N 3.15Å
343S70.1Confident67.6Low78 Ų78100 Ų10055%0.54551%0.51SS..Hα-helixtrans-67.5-40.1178.9-170.60000112.3Q339 Q340 L346 L347Q339-S343 VanDerWaalsContact O-CB 3.3Å; Q339-S343 WeakPolarHBondContact O-CB 3.38Å; Q339-S343 PolarHBondContact O-N 3.41Å; Q339-S343 VanDerWaalsContact O-N 3.1Å; Q340-S343 PolarHBondContact O-N 3.47Å; Q340-S343 VanDerWaalsContact O-N 3.17Å; S343-L346 WeakPolarHBondContact O-CB 3.34Å; S343-L346 PolarHBondContact O-N 2.9Å; S343-L347 PolarHBondContact O-N 2.98Å
344E73.2Confident65.2Low113 Ų113101.7 Ų101.753%0.52852%0.52SS..Hα-helixtrans-66.5-39.7174.4-79.1-161.8-153.600112.9Q340 L346 L347 R348Q340-E344 PolarHBondContact O-N 3.44Å; E344-L346 VanDerWaalsContact C-N 3.31Å; E344-L346 PolarHBondContact O-N 3.39Å; E344-L347 PolarHBondContact O-N 3.37Å; E344-R348 WeakPolarHBondContact O-CG 3.24Å; E344-R348 PolarHBondContact O-N 3.21Å; E344-R348 IonicContact OE2-CZ 3.98Å; E344-R348 IonicContact OE2-NH2 2.78Å; E344-R348 PolarHBondContact OE2-NH2 3.49Å
345A68.7Low62.9Low57 Ų57107.1 Ų107.147%0.47155%0.545SS..Hα-helixtrans-59.6-44176.100000111.4E341 A342 L347 R348 A349E341-A345 PolarHBondContact O-N 3.17Å; A342-A345 PolarHBondContact O-N 3.39Å; A345-L347 VanDerWaalsContact C-N 3.33Å; A345-L347 PolarHBondContact O-N 2.98Å; A345-R348 PolarHBondContact O-N 3.3Å; A345-A349 PolarHBondContact O-N 3Å
346L66.6Low60.5Low84 Ų84115 Ų11544%0.4458%0.58SS.*Hα-helixtrans-58-43.4176.4-158.986000112.2M241 A342 S343 E344 T350M241-L346 HydrophobicContact CG-CD1 3.44Å; M241-L346 VanDerWaalsContact CG-CD1 3.44Å; M241-L346 HydrophobicContact SD-CD1 4.45Å; A342-L346 PolarHBondContact O-N 3.02Å; A342-L346 VanDerWaalsContact O-N 3.15Å; S343-L346 WeakPolarHBondContact O-CB 3.34Å; S343-L346 PolarHBondContact O-N 2.9Å; E344-L346 VanDerWaalsContact C-N 3.31Å; E344-L346 PolarHBondContact O-N 3.39Å; L346-T350 PolarHBondContact O-OG1 3.39Å
347L67.7Low58.4Low127 Ų127114.5 Ų114.567%0.66559%0.587SS**Hα-helixtrans-66.3-43.5-175.7-165.272.2000112.1S343 E344 A345 A349 T350S343-L347 PolarHBondContact O-N 2.98Å; E344-L347 PolarHBondContact O-N 3.37Å; A345-L347 VanDerWaalsContact C-N 3.33Å; A345-L347 PolarHBondContact O-N 2.98Å; L347-A349 VanDerWaalsContact C-N 3.31Å; L347-A349 PolarHBondContact O-N 3.5Å; L347-T350 WeakPolarHBondContact O-CB 3.47Å; L347-T350 PolarHBondContact O-N 3.46Å; L347-T350 VanDerWaalsContact O-N 3.11Å; L347-T350 PolarHBondContact O-OG1 2.74Å
348R66Low55.9Low165 Ų165118.2 Ų118.262%0.62361%0.607SS**Hα-helixtrans-63.3-35.1-178.8-63.6172.3-161.6-1726.9112.5E344 A345 T350 T351E344-R348 WeakPolarHBondContact O-CG 3.24Å; E344-R348 PolarHBondContact O-N 3.21Å; E344-R348 IonicContact OE2-CZ 3.98Å; E344-R348 IonicContact OE2-NH2 2.78Å; E344-R348 PolarHBondContact OE2-NH2 3.49Å; A345-R348 PolarHBondContact O-N 3.3Å; R348-T350 PolarHBondContact O-N 2.81Å; R348-T351 PolarHBondContact O-N 3.44Å; R348-T351 PolarHBondContact O-OG1 3.31Å
349A60.3Low53.6Low44 Ų44119.5 Ų119.536%0.36462%0.623SS.*THydrogen-bonded Turntrans-63.4-17.4176.100000113.8M237 A345 L347M237-A349 HydrophobicContact CE-CB 4.47Å; M237-A349 HydrophobicContact CG-CB 4.17Å; M237-A349 HydrophobicContact SD-CB 3.93Å; A345-A349 PolarHBondContact O-N 3Å; L347-A349 VanDerWaalsContact C-N 3.31Å; L347-A349 PolarHBondContact O-N 3.5Å
350T54.6Low51.8Low105 Ų105125.2 Ų125.264%0.64465%0.649SS**THydrogen-bonded Turntrans-84-17-175.1-23.30000114L346 L347 R348L346-T350 PolarHBondContact O-OG1 3.39Å; L347-T350 WeakPolarHBondContact O-CB 3.47Å; L347-T350 PolarHBondContact O-N 3.46Å; L347-T350 VanDerWaalsContact O-N 3.11Å; L347-T350 PolarHBondContact O-OG1 2.74Å; R348-T350 PolarHBondContact O-N 2.81Å
351T52.5Low49.2Very low116 Ų116125.3 Ų125.371%0.71265%0.654SS**SBendtrans-96.9-8.6-16134.20000117.5R348R348-T351 PolarHBondContact O-N 3.44Å; R348-T351 PolarHBondContact O-OG1 3.31Å
352E41.1Very low46.7Very low180 Ų180126.2 Ų126.284%0.84167%0.666SS**  trans-100.15-163.6-56.4-163.4147.600116.3M354E352-M354 PolarHBondContact O-N 3.18Å
353A33.3Very low45Very low91 Ų91134.8 Ų134.875%0.75270%0.701SS**  trans-98.825.5-153.300000118.9
354M30.3Very low42.9Very low186 Ų186139.1 Ų139.192%0.91671%0.713SS**  trans-144111.5-178-70.2-170.617400116.3E352E352-M354 PolarHBondContact O-N 3.18Å
355Q30.9Very low40.7Very low205 Ų205142.7 Ų142.796%0.95873%0.729SS**  trans-147.8-178.5162.1-74.8-156.3-2.600112.5
356H28.5Very low39.3Very low174 Ų174146.3 Ų146.381%0.80675%0.745SS**  trans-145.1154.7-138-168.8-104.2000117.3
357N32Very low37.4Very low121 Ų121150.1 Ų150.165%0.64776%0.761SS**  trans81.8143.3153-132.3-10.9000124.1
358K28.1Very low35.9Very low207 Ų207152 Ų15290%0.977%0.766SS**  179.5178.3129.4-101.9176-179.2-177.90116.2
359L26.7Very low34.3Very low159 Ų159150.3 Ų150.383%0.83277%0.769SS**  trans-143.6167.6-160.6-104.2163.8000117.2
360H34.5Very low33Very low171 Ų171159.2 Ų159.279%0.79280%0.795SS**  trans-45.7169-173.8-114.3-90.6000124.3
361N22.3Very low32.2Very low137 Ų137160.9 Ų160.973%0.73381%0.806SS**  trans-177.9145.7144.6-106.3-12.2000122.1
362V24.2Very low31.4Very low118 Ų118164.6 Ų164.672%0.71582%0.817SS**  trans83.1162.3136.5173.90000125.5
363F34.4Very low31.3Very low193 Ų193160.6 Ų160.685%0.84682%0.815SS**  trans-156.8164.2-163.3-168.5-81.6000113.9
364E25.9Very low31.5Very low169 Ų169164 Ų16479%0.7982%0.82SS**  trans-157-164.1178.1-141.8153.9-14300120.6
365H26.1Very low31.9Very low187 Ų187157.9 Ų157.987%0.86681%0.805SS**  trans-130.8-152.2-152-103.7-56.5000122.4
366V39Very low32.6Very low134 Ų134155 Ų15581%0.81280%0.796SS**  trans-151.9155.2-153.1-176.20000118.3
367E26.1Very low33.7Very low163 Ų163152.3 Ų152.376%0.76278%0.78SS**  trans-165.6-170.7158.8-129.4-177.9-145.300120.9Q198Q198-E367 PolarHBondContact NE2-OE2 3.41Å
368E37.4Very low34.3Very low166 Ų166156.5 Ų156.578%0.77679%0.787SS**  trans-155.9174.8-158.7-153.9-171.4-12400120.6
369N31.7Very low35.6Very low130 Ų130148.7 Ų148.770%0.69576%0.756SS**  trans109.1162.7154.9-77.2-70.4000127.6
370Y33.3Very low37.7Very low231 Ų231147.2 Ų147.291%0.90675%0.745SS**  trans-152.3171.3-168.8-83.4-83.3000119.3
371T37.4Very low39.3Very low141 Ų141140 Ų14087%0.86571%0.712SS**  trans-155.3174.3-178.661.20000118.6
372M35.9Very low41.3Very low194 Ų194133.8 Ų133.896%0.95668%0.679SS**  trans-159.8179.3171.3-91.1-147.774.500118.2
373A39Very low43Very low95 Ų95131.5 Ų131.579%0.78567%0.668SS**  trans-143-167.2-160.700000120.2
374N37.4Very low44.1Very low163 Ų163127.6 Ų127.687%0.87266%0.656SS**  trans-147.5176-165.9-110.5-20.4000117.4Y377N374-Y377 PolarHBondContact O-OH 3.11Å
375G38.2Very low45.6Very low58 Ų58126.4 Ų126.460%0.59865%0.651SS**  trans-154.6-176.9174.600000113.8Y377G375-Y377 WeakPolarHBondContact CA-OH 3.27Å
376D46.4Very low47.2Very low144 Ų144120 Ų12077%0.7762%0.619SS**  cis-142.2177.95.1-177.620.3000110.3
377Y52.4Low47.9Very low118 Ų118116.8 Ų116.846%0.46361%0.607SS.*  trans-133.7126.8-135.8-42.5-62.9000122.1M175 N374 G375M175-Y377 HydrophobicContact CE-CD1 3.47Å; M175-Y377 VanDerWaalsContact CE-CD1 3.47Å; M175-Y377 HydrophobicContact CE-CD2 3.96Å; M175-Y377 HydrophobicContact CE-CE1 4.13Å; M175-Y377 HydrophobicContact CE-CG 3.37Å; M175-Y377 HydrophobicContact SD-CG 4.09Å; N374-Y377 PolarHBondContact O-OH 3.11Å; G375-Y377 WeakPolarHBondContact CA-OH 3.27Å
378R44.7Very low49.7Very low209 Ų209117 Ų11779%0.78961%0.613SS**  trans-124.7127.8137.5161.3-177.3156.5159.7-4.8106.5
379V54.6Low51.1Low43 Ų43110.5 Ų110.526%0.26159%0.585SS.*EExtended strand (participates in β ladder)trans-127.9124.2-172.1179.50000113.5M175 L381M175-V379 HydrophobicContact CE-CB 4.18Å; M175-V379 HydrophobicContact CE-CG2 3.39Å; M175-V379 HydrophobicContact CG-CB 4.26Å; M175-V379 HydrophobicContact CG-CG2 4.46Å; M175-V379 HydrophobicContact SD-CB 4.02Å; M175-V379 HydrophobicContact SD-CG2 3.74Å; V379-L381 HydrophobicContact CB-CD2 4.39Å; V379-L381 HydrophobicContact CG1-CD2 3.63Å; V379-L381 HydrophobicContact CG1-CG 4.17Å
380E70.6Confident52.9Low128 Ų128108.4 Ų108.460%0.59858%0.579SS**EExtended strand (participates in β ladder)trans-81.2119159.4-167.3125-102.700107.4N137N137-E380 PolarHBondContact ND2-OE1 3.26Å
381L68.7Low54.9Low20 Ų20100.9 Ų100.911%0.10555%0.552CS.*  trans-90.8-35.4-162.5-72.1168.5000112.9I135 R136 I138 M175 H178 V379I135-L381 HydrophobicContact CG2-CD1 4.14Å; R136-L381 PolarHBondContact O-N 3.16Å; I138-L381 HydrophobicContact CB-CD1 4.16Å; I138-L381 HydrophobicContact CD1-CD1 3.53Å; I138-L381 HydrophobicContact CG1-CD1 3.59Å; M175-L381 HydrophobicContact CG-CD2 4.26Å; H178-L381 HydrophobicContact CB-CD1 4.49Å; H178-L381 HydrophobicContact CB-CD2 4.08Å; H178-L381 PolarHBondContact CE1-O 2.96Å; V379-L381 HydrophobicContact CB-CD2 4.39Å; V379-L381 HydrophobicContact CG1-CD2 3.63Å; V379-L381 HydrophobicContact CG1-CG 4.17Å
382T63.5Low56.7Low5 Ų5101 Ų1013%0.03154%0.536CS..  trans-122.9118.2177.254.50000112.5R136 I150 H178 M182 Y386R136-T382 WeakPolarHBondContact CA-OG1 3.45Å; R136-T382 PolarHBondContact O-N 2.71Å; I150-T382 HydrophobicContact CD1-CG2 3.87Å; I150-T382 WeakPolarHBondContact CD1-OG1 3.28Å; H178-T382 WeakPolarHBondContact NE2-CG2 3.18Å; M182-T382 HydrophobicContact CE-CG2 3.77Å; T382-Y386 HydrophobicContact CG2-CD2 4.07Å; T382-Y386 HydrophobicContact CG2-CG 4.22Å
383S60.4Low58.7Low70 Ų7092.4 Ų92.449%0.4949%0.494SS..  trans-62159.6150.8-178.70000110.4E385 Y386S383-E385 PolarHBondContact O-N 3.35Å; S383-E385 VanDerWaalsContact O-N 3.13Å; S383-Y386 WeakPolarHBondContact O-CD2 3.4Å; S383-Y386 PolarHBondContact O-N 3.17Å; S383-Y386 VanDerWaalsContact O-N 3.16Å
384D57.3Low60.5Low111 Ų11191.7 Ų91.759%0.59448%0.476SS*.G310 helixtrans-67.5-9.2175.6-66.4-33.7000112.3R136 Y386 A387R136-D384 IonicContact CZ-OD1 2.86Å; R136-D384 IonicContact NH1-OD1 3.72Å; R136-D384 PolarHBondContact NH1-OD1 3.16Å; R136-D384 VanDerWaalsContact NH1-OD1 3.08Å; R136-D384 IonicContact NH2-OD1 3.25Å; D384-Y386 PolarHBondContact O-N 3.45Å; D384-Y386 VanDerWaalsContact O-N 3.16Å; D384-A387 PolarHBondContact O-N 3.23Å
385E56.7Low62.7Low145 Ų14591.9 Ų91.968%0.67847%0.471SS*.G310 helixtrans-54.3-24165.3-69.5-172.8166.100114.4K186 S383 A387K186-E385 IonicContact NZ-OE2 2.64Å; S383-E385 PolarHBondContact O-N 3.35Å; S383-E385 VanDerWaalsContact O-N 3.13Å; E385-A387 VanDerWaalsContact C-N 3.29Å; E385-A387 PolarHBondContact O-N 3.01Å
386Y60.3Low65.1Low52 Ų5291.2 Ų91.220%0.20445%0.451CS..G310 helixtrans-89.412.8-177.4-61-74.8000113.5M182 K186 T382 S383 D384 N388 V389M182-Y386 HydrophobicContact CB-CD1 4.36Å; M182-Y386 HydrophobicContact CB-CE1 3.84Å; M182-Y386 HydrophobicContact CG-CD1 4.09Å; M182-Y386 HydrophobicContact CG-CE1 4.02Å; M182-Y386 HydrophobicContact SD-CD1 3.57Å; M182-Y386 VanDerWaalsContact SD-CD1 3.57Å; M182-Y386 HydrophobicContact SD-CE1 4.06Å; M182-Y386 HydrophobicContact SD-CG 4.14Å; K186-Y386 WeakPolarHBondContact CE-OH 3.49Å; K186-Y386 PolarHBondContact NZ-OH 3.31Å; T382-Y386 HydrophobicContact CG2-CD2 4.07Å; T382-Y386 HydrophobicContact CG2-CG 4.22Å; S383-Y386 WeakPolarHBondContact O-CD2 3.4Å; S383-Y386 PolarHBondContact O-N 3.17Å; S383-Y386 VanDerWaalsContact O-N 3.16Å; D384-Y386 PolarHBondContact O-N 3.45Å; D384-Y386 VanDerWaalsContact O-N 3.16Å; Y386-N388 PolarHBondContact O-N 3.46Å; Y386-V389 WeakPolarHBondContact O-CG2 3.4Å
387A54.6Low67.2Low67 Ų6788.7 Ų88.755%0.55443%0.434SS*.THydrogen-bonded Turntrans-67.2128.7165.600000110.5D384 E385D384-A387 PolarHBondContact O-N 3.23Å; E385-A387 VanDerWaalsContact C-N 3.29Å; E385-A387 PolarHBondContact O-N 3.01Å
388N62.8Low69Low167 Ų16783.8 Ų83.889%0.89342%0.417SS*.THydrogen-bonded Turntrans71.424.2176.4-43.5-53.2000117.4Y386Y386-N388 PolarHBondContact O-N 3.46Å
389V67.1Low71.1Confident29 Ų2975.3 Ų75.318%0.17639%0.391CS..  trans-65.5139.7169.4-91.40000112.5M182 R185 Y386M182-V389 HydrophobicContact SD-CG2 4.31Å; R185-V389 HydrophobicContact CB-CB 4.28Å; R185-V389 HydrophobicContact CB-CG1 3.92Å; R185-V389 HydrophobicContact CG-CB 4.39Å; Y386-V389 WeakPolarHBondContact O-CG2 3.4Å
390P70.1Confident72.5Confident87 Ų8774.6 Ų74.657%0.56539%0.386SS*.  trans-55.7146.1179.6-27.835.5000114.3R185R185-P390 VanDerWaalsContact CZ-O 3.24Å; R185-P390 PolarHBondContact NE-O 3.15Å; R185-P390 PolarHBondContact NH2-O 3.41Å
391Q75.1Confident73.2Confident73 Ų7371.6 Ų71.634%0.34137%0.372SS..  trans-120.860.4179.1-61.1-171.929.600111S133 E393 I394S133-Q391 VanDerWaalsContact OG-CD 3.32Å; S133-Q391 PolarHBondContact OG-NE2 3.05Å; Q391-E393 PolarHBondContact O-N 3.35Å; Q391-E393 VanDerWaalsContact O-N 3.11Å; Q391-I394 HydrophobicContact CB-CD1 3.66Å; Q391-I394 HydrophobicContact CB-CG1 3.97Å; Q391-I394 VanDerWaalsContact O-CB 3.3Å; Q391-I394 WeakPolarHBondContact O-CB 3.39Å; Q391-I394 WeakPolarHBondContact O-CG1 3.36Å; Q391-I394 PolarHBondContact O-N 3.23Å
392W75.2Confident73.9Confident144 Ų14478.4 Ų78.455%0.54540%0.396SS..THydrogen-bonded Turntrans-60-18.1-177.758.3-82.4000114.1I394W392-I394 PolarHBondContact O-N 3.11Å
393E76.7Confident75.1Confident12 Ų1281.5 Ų81.56%0.05641%0.413CS..THydrogen-bonded Turntrans-65.7-21.2168.467.7-86.6-157.900114.1L113 Y181 R185 Q391 R396L113-E393 HydrophobicContact CD2-CB 4.05Å; Y181-E393 VanDerWaalsContact CE2-OE1 3.23Å; Y181-E393 WeakPolarHBondContact CE2-OE1 3.48Å; Y181-E393 PolarHBondContact OH-OE1 3.23Å; R185-E393 IonicContact CZ-OE2 3.62Å; R185-E393 VanDerWaalsContact NH2-CD 3.28Å; R185-E393 IonicContact NH2-OE1 3.46Å; R185-E393 PolarHBondContact NH2-OE1 2.88Å; R185-E393 VanDerWaalsContact NH2-OE1 3.08Å; R185-E393 IonicContact NH2-OE2 3.61Å; R185-E393 PolarHBondContact NH2-OE2 3.27Å; Q391-E393 PolarHBondContact O-N 3.35Å; Q391-E393 VanDerWaalsContact O-N 3.11Å; E393-R396 WeakPolarHBondContact O-CB 3.31Å; E393-R396 PolarHBondContact O-N 2.99Å
394I77Confident76.3Confident81 Ų8183.6 Ų83.642%0.41542%0.415SS..THydrogen-bonded Turntrans-67.4-41.2177.5-65.8178.5000110.7Q391 W392 R396 R448Q391-I394 HydrophobicContact CB-CD1 3.66Å; Q391-I394 HydrophobicContact CB-CG1 3.97Å; Q391-I394 VanDerWaalsContact O-CB 3.3Å; Q391-I394 WeakPolarHBondContact O-CB 3.39Å; Q391-I394 WeakPolarHBondContact O-CG1 3.36Å; Q391-I394 PolarHBondContact O-N 3.23Å; W392-I394 PolarHBondContact O-N 3.11Å; I394-R396 VanDerWaalsContact C-N 3.25Å; I394-R396 PolarHBondContact O-N 3.28Å; I394-R448 HydrophobicContact CG2-CG 4.42Å; I394-R448 VanDerWaalsContact O-CD 3.26Å; I394-R448 WeakPolarHBondContact O-CD 3.27Å; I394-R448 PolarHBondContact O-NH1 3.16Å
395E83.3Confident77.8Confident166 Ų16683.1 Ų83.178%0.77641%0.412SS*.THydrogen-bonded Turntrans-86.93.9-178.5-64.5178.8172.900112.7Q397E395-Q397 PolarHBondContact O-N 3.39Å
396R89Confident79.4Confident44 Ų4477.6 Ų77.617%0.16639%0.387CS..  trans-68.3134.4-175.9-171.7165.2169.6166.2-5.4111.9Q86 D87 E393 I394 Y444 R448Q86-R396 VanDerWaalsContact NE2-NH2 3.12Å; D87-R396 IonicContact OD1-NH2 3.54Å; D87-R396 PolarHBondContact OD1-NH2 3.2Å; E393-R396 WeakPolarHBondContact O-CB 3.31Å; E393-R396 PolarHBondContact O-N 2.99Å; I394-R396 VanDerWaalsContact C-N 3.25Å; I394-R396 PolarHBondContact O-N 3.28Å; R396-Y444 HydrophobicContact CB-CD1 4.06Å; R396-Y444 HydrophobicContact CB-CE1 4.47Å; R396-Y444 HydrophobicContact CB-CG 4.13Å; R396-Y444 HydrophobicContact CG-CD1 4.02Å; R396-Y444 HydrophobicContact CG-CD2 3.99Å; R396-Y444 HydrophobicContact CG-CE1 4.01Å; R396-Y444 HydrophobicContact CG-CE2 3.94Å; R396-Y444 HydrophobicContact CG-CG 4.05Å; R396-Y444 PolarHBondContact NE-OH 3.47Å; R396-Y444 VanDerWaalsContact NE-OH 3.1Å; R396-Y444 PolarHBondContact NH2-OH 2.86Å; R396-Y444 WeakPolarHBondContact O-CB 3.28Å; R396-R448 PolarHBondContact O-NH1 2.96Å
397Q90.1Very high80.8Confident91 Ų9177 Ų7743%0.42539%0.386SS..  trans-109.8161.7168.2-64.9162.9-42.600108.5E395 E401 R402E395-Q397 PolarHBondContact O-N 3.39Å; Q397-E401 HydrophobicContact CB-CB 4.37Å; Q397-R402 HydrophobicContact CB-CG 4.32Å
398T91.1Very high82.6Confident16 Ų1677.9 Ų77.910%0.09838%0.382CS..  trans-69.9160.5170.6620000111.9D87 L400 E401 R402 D442 Y444D87-T398 HydrophobicContact CB-CG2 4.05Å; D87-T398 WeakPolarHBondContact OD2-CA 3.48Å; D87-T398 WeakPolarHBondContact OD2-CB 3.31Å; T398-L400 PolarHBondContact O-N 3.37Å; T398-E401 WeakPolarHBondContact CB-OE2 3.48Å; T398-E401 PolarHBondContact N-OE2 2.86Å; T398-E401 WeakPolarHBondContact OG1-CB 3.29Å; T398-E401 WeakPolarHBondContact OG1-CG 3.38Å; T398-E401 PolarHBondContact OG1-N 3.14Å; T398-E401 VanDerWaalsContact OG1-N 3.14Å; T398-E401 PolarHBondContact OG1-OE2 3.21Å; T398-R402 WeakPolarHBondContact O-CG 3.48Å; T398-R402 PolarHBondContact O-N 3.34Å; T398-D442 HydrophobicContact CG2-CB 4.19Å; T398-Y444 HydrophobicContact CG2-CD2 3.94Å; T398-Y444 HydrophobicContact CG2-CE2 4.07Å
399A88.1Confident83.9Confident30 Ų3073.8 Ų73.825%0.24835%0.354CS..THydrogen-bonded Turntrans-62.5-32172.600000112.1D87 R402 N403D87-A399 PolarHBondContact OD2-N 2.88Å; A399-R402 PolarHBondContact O-N 3.4Å; A399-N403 PolarHBondContact O-N 2.73Å
400L84.2Confident85.1Confident29 Ų2972.6 Ų72.615%0.15235%0.346CS..THydrogen-bonded Turntrans-74.4-44.5179.9-55.6-179.1000112I84 T398 R402 N403 I406 L410I84-L400 HydrophobicContact CG1-CD2 4.43Å; T398-L400 PolarHBondContact O-N 3.37Å; L400-R402 PolarHBondContact O-N 2.97Å; L400-R402 VanDerWaalsContact O-N 3.08Å; L400-N403 CarbonylContact O-C 3.54Å; L400-N403 PolarHBondContact O-N 3.36Å; L400-I406 HydrophobicContact CD2-CG2 3.83Å; L400-L410 HydrophobicContact CD1-CD1 3.63Å; L400-L410 HydrophobicContact CD2-CD1 3.65Å; L400-L410 HydrophobicContact CG-CD1 4.26Å
401E85.2Confident86.2Confident64 Ų6471.5 Ų71.530%0.29934%0.336SS..THydrogen-bonded Turntrans-57.4-23.8171.9-76.9170118.100113.4Q397 T398 K445Q397-E401 HydrophobicContact CB-CB 4.37Å; T398-E401 WeakPolarHBondContact CB-OE2 3.48Å; T398-E401 PolarHBondContact N-OE2 2.86Å; T398-E401 WeakPolarHBondContact OG1-CB 3.29Å; T398-E401 WeakPolarHBondContact OG1-CG 3.38Å; T398-E401 PolarHBondContact OG1-N 3.14Å; T398-E401 VanDerWaalsContact OG1-N 3.14Å; T398-E401 PolarHBondContact OG1-OE2 3.21Å; E401-K445 IonicContact OE1-NZ 3.24Å; E401-K445 PolarHBondContact OE1-NZ 3.17Å
402R84.8Confident87.1Confident164 Ų16471 Ų7162%0.61934%0.344SS*.THydrogen-bonded Turntrans-87.5-10.7177.3-71.2173.6170.8-178.1-2.3113.7Q397 T398 A399 L400Q397-R402 HydrophobicContact CB-CG 4.32Å; T398-R402 WeakPolarHBondContact O-CG 3.48Å; T398-R402 PolarHBondContact O-N 3.34Å; A399-R402 PolarHBondContact O-N 3.4Å; L400-R402 PolarHBondContact O-N 2.97Å; L400-R402 VanDerWaalsContact O-N 3.08Å
403N87.6Confident88.1Confident70 Ų7065 Ų6537%0.37432%0.323SS..  trans-134.381-179.5-168.9-20.9000110.2A399 L400 N405 I406 Q407A399-N403 PolarHBondContact O-N 2.73Å; L400-N403 CarbonylContact O-C 3.54Å; L400-N403 PolarHBondContact O-N 3.36Å; N403-N405 PolarHBondContact O-N 2.86Å; N403-N405 VanDerWaalsContact O-N 3.13Å; N403-I406 HydrophobicContact CB-CB 4.39Å; N403-I406 HydrophobicContact CB-CD1 4.44Å; N403-I406 HydrophobicContact CB-CG1 4.47Å; N403-I406 VanDerWaalsContact ND2-CD1 3.26Å; N403-I406 WeakPolarHBondContact ND2-CD1 3.42Å; N403-I406 PolarHBondContact O-N 3.45Å; N403-I406 PolarHBondContact OD1-N 3.38Å; N403-Q407 PolarHBondContact O-N 2.93Å
404Q86.4Confident88.9Confident113 Ų11366.6 Ų66.653%0.52833%0.331SS..Hα-helixtrans-51.8-37.6-177.6-16664.851.300112.8I406 Q407 D408Q404-I406 PolarHBondContact O-N 3.39Å; Q404-Q407 PolarHBondContact O-N 3.37Å; Q404-D408 PolarHBondContact NE2-OD1 3Å; Q404-D408 WeakPolarHBondContact O-CB 3.4Å; Q404-D408 PolarHBondContact O-N 3.1Å
405N89.2Confident89.8Confident102 Ų10265.4 Ų65.455%0.54533%0.333SS..Hα-helixtrans-62.3-42.1177.8-175.7-2.2000112.1N403 R409N403-N405 PolarHBondContact O-N 2.86Å; N403-N405 VanDerWaalsContact O-N 3.13Å; N405-R409 WeakPolarHBondContact O-CB 3.26Å; N405-R409 WeakPolarHBondContact O-CD 3.49Å; N405-R409 WeakPolarHBondContact O-CG 3.3Å; N405-R409 PolarHBondContact O-N 3.03Å; N405-R409 WeakPolarHBondContact OD1-CD 3.41Å
406I88.6Confident90.3Very high28 Ų2860.2 Ų60.214%0.14431%0.311CS..Hα-helixtrans-69.2-39.9173.7-63.7-179.8000110.6L14 L400 N403 Q404 R409 L410L14-I406 HydrophobicContact CD2-CG2 3.7Å; L400-I406 HydrophobicContact CD2-CG2 3.83Å; N403-I406 HydrophobicContact CB-CB 4.39Å; N403-I406 HydrophobicContact CB-CD1 4.44Å; N403-I406 HydrophobicContact CB-CG1 4.47Å; N403-I406 VanDerWaalsContact ND2-CD1 3.26Å; N403-I406 WeakPolarHBondContact ND2-CD1 3.42Å; N403-I406 PolarHBondContact O-N 3.45Å; N403-I406 PolarHBondContact OD1-N 3.38Å; Q404-I406 PolarHBondContact O-N 3.39Å; I406-R409 PolarHBondContact O-N 3.09Å; I406-L410 HydrophobicContact CG2-CD1 4Å; I406-L410 HydrophobicContact CG2-CG 4.21Å; I406-L410 WeakPolarHBondContact O-CB 3.32Å; I406-L410 WeakPolarHBondContact O-CG 3.35Å; I406-L410 PolarHBondContact O-N 2.93Å
407Q90.1Very high90.5Very high41 Ų4158.1 Ų58.119%0.19230%0.303CS..Hα-helixtrans-60.5-54177.5-178.560.148.300112.1N403 Q404 R409 L410 D411N403-Q407 PolarHBondContact O-N 2.93Å; Q404-Q407 PolarHBondContact O-N 3.37Å; Q407-R409 PolarHBondContact O-N 3.08Å; Q407-L410 PolarHBondContact O-N 3.07Å; Q407-L410 VanDerWaalsContact O-N 3.12Å; Q407-D411 VanDerWaalsContact NE2-CG 3.29Å; Q407-D411 PolarHBondContact NE2-OD1 3.35Å; Q407-D411 PolarHBondContact NE2-OD2 3.17Å; Q407-D411 PolarHBondContact O-N 3.35Å
408D92.1Very high90.7Very high85 Ų8556.8 Ų56.846%0.45530%0.297SS..Hα-helixtrans-56.1-38.6179.8-63.9-21.5000111.5Q404 A412Q404-D408 PolarHBondContact NE2-OD1 3Å; Q404-D408 WeakPolarHBondContact O-CB 3.4Å; Q404-D408 PolarHBondContact O-N 3.1Å; D408-A412 WeakPolarHBondContact O-CB 3.38Å; D408-A412 PolarHBondContact O-N 3.49Å
409R91.1Very high90.8Very high81 Ų8163.2 Ų63.231%0.30632%0.324SS..Hα-helixtrans-79.8-29.4-179.6-68.1179.362.1-135.2-10.7113.5W65 E68 N405 I406 Q407 L413W65-R409 HydrophobicContact CH2-CB 3.6Å; W65-R409 HydrophobicContact CZ2-CB 4.03Å; E68-R409 IonicContact OE1-CZ 3.89Å; E68-R409 VanDerWaalsContact OE1-CZ 3.31Å; E68-R409 IonicContact OE1-NH1 2.67Å; E68-R409 PolarHBondContact OE1-NH1 3.34Å; E68-R409 IonicContact OE1-NH2 2.77Å; E68-R409 PolarHBondContact OE1-NH2 3.27Å; E68-R409 IonicContact OE2-CZ 3.66Å; E68-R409 IonicContact OE2-NH1 2.9Å; E68-R409 PolarHBondContact OE2-NH1 2.68Å; E68-R409 IonicContact OE2-NH2 2.79Å; E68-R409 PolarHBondContact OE2-NH2 3.04Å; N405-R409 WeakPolarHBondContact O-CB 3.26Å; N405-R409 WeakPolarHBondContact O-CD 3.49Å; N405-R409 WeakPolarHBondContact O-CG 3.3Å; N405-R409 PolarHBondContact O-N 3.03Å; N405-R409 WeakPolarHBondContact OD1-CD 3.41Å; I406-R409 PolarHBondContact O-N 3.09Å; Q407-R409 PolarHBondContact O-N 3.08Å; R409-L413 WeakPolarHBondContact O-CB 3.3Å; R409-L413 PolarHBondContact O-N 3.09Å
410L92.3Very high91Very high3 Ų365.3 Ų65.32%0.01633%0.329CS..Hα-helixtrans-68.4-39.9167.7-79.8177.2000111.5E10 L14 W65 L400 I406 Q407 L413 N414E10-L410 HydrophobicContact CB-CD2 4.16Å; E10-L410 HydrophobicContact CG-CB 4.32Å; E10-L410 HydrophobicContact CG-CD2 4.12Å; L14-L410 HydrophobicContact CB-CD2 3.96Å; L14-L410 HydrophobicContact CD2-CD1 3.85Å; L14-L410 HydrophobicContact CD2-CD2 3.92Å; L14-L410 HydrophobicContact CD2-CG 4.13Å; W65-L410 HydrophobicContact CH2-CD2 4.45Å; W65-L410 HydrophobicContact CH2-CG 4.4Å; W65-L410 HydrophobicContact CZ2-CD2 4.26Å; L400-L410 HydrophobicContact CD1-CD1 3.63Å; L400-L410 HydrophobicContact CD2-CD1 3.65Å; L400-L410 HydrophobicContact CG-CD1 4.26Å; I406-L410 HydrophobicContact CG2-CD1 4Å; I406-L410 HydrophobicContact CG2-CG 4.21Å; I406-L410 WeakPolarHBondContact O-CB 3.32Å; I406-L410 WeakPolarHBondContact O-CG 3.35Å; I406-L410 PolarHBondContact O-N 2.93Å; Q407-L410 PolarHBondContact O-N 3.07Å; Q407-L410 VanDerWaalsContact O-N 3.12Å; L410-L413 PolarHBondContact O-N 3.04Å; L410-N414 VanDerWaalsContact O-CB 3.32Å; L410-N414 WeakPolarHBondContact O-CB 3.38Å; L410-N414 PolarHBondContact O-N 3.49Å
411D93.2Very high91.6Very high65 Ų6564.9 Ų64.935%0.34833%0.326SS..Hα-helixtrans-68.5-37.7175.7-72.8-34.6000111.4Q407 N414 A415Q407-D411 VanDerWaalsContact NE2-CG 3.29Å; Q407-D411 PolarHBondContact NE2-OD1 3.35Å; Q407-D411 PolarHBondContact NE2-OD2 3.17Å; Q407-D411 PolarHBondContact O-N 3.35Å; D411-N414 PolarHBondContact O-N 3.31Å; D411-A415 VanDerWaalsContact O-CB 3.3Å; D411-A415 WeakPolarHBondContact O-CB 3.42Å; D411-A415 PolarHBondContact O-N 3.06Å
412A94.5Very high92Very high63 Ų6363.7 Ų63.752%0.52132%0.321SS..Hα-helixtrans-63.2-41.617000000112.7D408 A415 D416D408-A412 WeakPolarHBondContact O-CB 3.38Å; D408-A412 PolarHBondContact O-N 3.49Å; A412-A415 PolarHBondContact O-N 3.19Å; A412-D416 PolarHBondContact O-N 3.38Å
413L94.4Very high92.4Very high18 Ų1861.3 Ų61.39%0.09432%0.317CS..Hα-helixtrans-63.5-45.4173.9174.363.7000111.4E10 V13 K61 R409 L410 A415 D416 L417E10-L413 HydrophobicContact CB-CD2 3.98Å; E10-L413 HydrophobicContact CB-CG 4.16Å; V13-L413 HydrophobicContact CB-CD2 3.86Å; V13-L413 HydrophobicContact CG1-CD2 3.9Å; V13-L413 HydrophobicContact CG2-CD2 4.31Å; K61-L413 HydrophobicContact CD-CD1 4.49Å; R409-L413 WeakPolarHBondContact O-CB 3.3Å; R409-L413 PolarHBondContact O-N 3.09Å; L410-L413 PolarHBondContact O-N 3.04Å; L413-A415 PolarHBondContact O-N 3.13Å; L413-D416 PolarHBondContact O-N 2.93Å; L413-D416 VanDerWaalsContact O-N 3.13Å; L413-L417 HydrophobicContact CD1-CD1 4.24Å; L413-L417 HydrophobicContact CD1-CG 4.11Å; L413-L417 HydrophobicContact CG-CD1 4.08Å; L413-L417 HydrophobicContact CG-CG 4.36Å; L413-L417 WeakPolarHBondContact O-CG 3.39Å; L413-L417 PolarHBondContact O-N 2.89Å
414N94.5Very high92.7Very high44 Ų4465.5 Ų65.524%0.23534%0.339CS..Hα-helixtrans-60.6-44.7177.2179.658.1000111.3E10 L410 D411 D416 L417 E418E10-N414 HydrophobicContact CB-CB 4.06Å; E10-N414 HydrophobicContact CG-CB 4.07Å; L410-N414 VanDerWaalsContact O-CB 3.32Å; L410-N414 WeakPolarHBondContact O-CB 3.38Å; L410-N414 PolarHBondContact O-N 3.49Å; D411-N414 PolarHBondContact O-N 3.31Å; N414-D416 PolarHBondContact O-N 2.91Å; N414-L417 PolarHBondContact O-N 3Å; N414-E418 WeakPolarHBondContact O-CB 3.41Å; N414-E418 PolarHBondContact O-N 3.35Å
415A95Very high93.1Very high56 Ų5664.5 Ų64.546%0.46333%0.333SS..Hα-helixtrans-65.1-24.5175.200000113.4D411 A412 L413 K419D411-A415 VanDerWaalsContact O-CB 3.3Å; D411-A415 WeakPolarHBondContact O-CB 3.42Å; D411-A415 PolarHBondContact O-N 3.06Å; A412-A415 PolarHBondContact O-N 3.19Å; L413-A415 PolarHBondContact O-N 3.13Å; A415-K419 VanDerWaalsContact O-CE 3.3Å; A415-K419 WeakPolarHBondContact O-CE 3.43Å; A415-K419 WeakPolarHBondContact O-CG 3.49Å
416D93.9Very high93.4Very high57 Ų5761.3 Ų61.331%0.30532%0.317SS..Hα-helixtrans-80.8-42171.6-167.463.6000112.9K61 A412 L413 N414 K419K61-D416 IonicContact NZ-OD2 3.65Å; K61-D416 PolarHBondContact NZ-OD2 2.69Å; A412-D416 PolarHBondContact O-N 3.38Å; L413-D416 PolarHBondContact O-N 2.93Å; L413-D416 VanDerWaalsContact O-N 3.13Å; N414-D416 PolarHBondContact O-N 2.91Å; D416-K419 WeakPolarHBondContact O-CB 3.48Å; D416-K419 PolarHBondContact O-N 3.09Å; D416-K419 IonicContact OD1-NZ 3.3Å; D416-K419 PolarHBondContact OD1-NZ 3.02Å
417L94.5Very high93.7Very high0 Ų062.3 Ų62.30%033%0.325CS..Hα-helixtrans-61.3-45.7175.7-70.4176.4000111.2P9 E10 Y51 L53 W58 K61 L413 N414 K419 M420 R421P9-L417 HydrophobicContact CB-CD1 3.97Å; E10-L417 HydrophobicContact CB-CD1 4.49Å; Y51-L417 HydrophobicContact CD1-CB 4.12Å; Y51-L417 WeakPolarHBondContact CD1-O 3.37Å; Y51-L417 VanDerWaalsContact CE1-C 3.45Å; Y51-L417 HydrophobicContact CE1-CB 3.72Å; Y51-L417 WeakPolarHBondContact CE1-O 3.33Å; L53-L417 HydrophobicContact CD1-CD2 3.72Å; W58-L417 HydrophobicContact CH2-CD1 4.39Å; W58-L417 HydrophobicContact CH2-CD2 3.74Å; W58-L417 HydrophobicContact CZ3-CD1 4.37Å; W58-L417 HydrophobicContact CZ3-CD2 3.71Å; K61-L417 HydrophobicContact CD-CD2 4.04Å; L413-L417 HydrophobicContact CD1-CD1 4.24Å; L413-L417 HydrophobicContact CD1-CG 4.11Å; L413-L417 HydrophobicContact CG-CD1 4.08Å; L413-L417 HydrophobicContact CG-CG 4.36Å; L413-L417 WeakPolarHBondContact O-CG 3.39Å; L413-L417 PolarHBondContact O-N 2.89Å; N414-L417 PolarHBondContact O-N 3Å; L417-K419 PolarHBondContact O-N 3.41Å; L417-K419 VanDerWaalsContact O-N 3.11Å; L417-M420 PolarHBondContact O-N 3.41Å; L417-R421 PolarHBondContact O-N 3.21Å
418E93.1Very high93.9Very high63 Ų6365.6 Ų65.629%0.29434%0.34SS..Hα-helixtrans-56.8-31.2-176.6-167.661.9-14300113.2N414 M420 R421 Q423N414-E418 WeakPolarHBondContact O-CB 3.41Å; N414-E418 PolarHBondContact O-N 3.35Å; E418-M420 PolarHBondContact O-N 3.25Å; E418-R421 VanDerWaalsContact CD-CD 3.46Å; E418-R421 WeakPolarHBondContact O-CB 3.35Å; E418-R421 PolarHBondContact O-N 3.43Å; E418-R421 WeakPolarHBondContact OE1-CD 3.4Å; E418-R421 IonicContact OE1-NH1 2.65Å; E418-R421 WeakPolarHBondContact OE2-CD 3.48Å; E418-R421 IonicContact OE2-CZ 2.66Å; E418-R421 IonicContact OE2-NE 2.82Å; E418-R421 IonicContact OE2-NH1 3.11Å; E418-R421 PolarHBondContact OE2-NH1 3.21Å; E418-Q423 PolarHBondContact OE1-NE2 3.08Å
419K93.7Very high94.1Very high152 Ų15264.2 Ų64.266%0.66133%0.329SS*.THydrogen-bonded Turntrans-58.8-30.5174.4-56.6166.9-167.2162.90113.2A415 D416 L417A415-K419 VanDerWaalsContact O-CE 3.3Å; A415-K419 WeakPolarHBondContact O-CE 3.43Å; A415-K419 WeakPolarHBondContact O-CG 3.49Å; D416-K419 WeakPolarHBondContact O-CB 3.48Å; D416-K419 PolarHBondContact O-N 3.09Å; D416-K419 IonicContact OD1-NZ 3.3Å; D416-K419 PolarHBondContact OD1-NZ 3.02Å; L417-K419 PolarHBondContact O-N 3.41Å; L417-K419 VanDerWaalsContact O-N 3.11Å
420M93.7Very high94.4Very high74 Ų7460.4 Ų60.437%0.36532%0.315SS..THydrogen-bonded Turntrans-103.56.4-175.5-58.9-57.5-62.700112.3Y51 K52 L53 L417 E418Y51-M420 WeakPolarHBondContact CA-O 3.36Å; K52-M420 HydrophobicContact CB-CE 4.29Å; K52-M420 PolarHBondContact N-O 2.83Å; K52-M420 WeakPolarHBondContact O-CE 3.42Å; L53-M420 HydrophobicContact CD2-CB 4.28Å; L53-M420 HydrophobicContact CD2-CE 4.45Å; L53-M420 HydrophobicContact CD2-CG 4.07Å; L53-M420 HydrophobicContact CG-CB 4.3Å; L417-M420 PolarHBondContact O-N 3.41Å; E418-M420 PolarHBondContact O-N 3.25Å
421R95.1Very high94.5Very high20 Ų2064 Ų648%0.07534%0.337CS..BIsolated β-bridgetrans-73139.8-173.4-161.4171.5-162.1174.80.7112.3Q50 Y51 L417 E418 M434Q50-R421 CarbonylContact O-C 3.52Å; Q50-R421 WeakPolarHBondContact O-CA 3.23Å; Q50-R421 WeakPolarHBondContact O-CG 3.4Å; Y51-R421 HydrophobicContact CD1-CB 3.91Å; Y51-R421 HydrophobicContact CD1-CG 4.14Å; Y51-R421 HydrophobicContact CE1-CB 3.58Å; Y51-R421 HydrophobicContact CE1-CG 3.6Å; Y51-R421 PolarHBondContact OH-NE 3Å; L417-R421 PolarHBondContact O-N 3.21Å; E418-R421 VanDerWaalsContact CD-CD 3.46Å; E418-R421 WeakPolarHBondContact O-CB 3.35Å; E418-R421 PolarHBondContact O-N 3.43Å; E418-R421 WeakPolarHBondContact OE1-CD 3.4Å; E418-R421 IonicContact OE1-NH1 2.65Å; E418-R421 WeakPolarHBondContact OE2-CD 3.48Å; E418-R421 IonicContact OE2-CZ 2.66Å; E418-R421 IonicContact OE2-NE 2.82Å; E418-R421 IonicContact OE2-NH1 3.11Å; E418-R421 PolarHBondContact OE2-NH1 3.21Å; R421-M434 PolarHBondContact NH1-SD 3.17Å
422D94.4Very high94.7Very high38 Ų3862.1 Ų62.120%0.20333%0.327CS..  trans-90.3112.1164.9-152.5-24.4000110.3Q50 K52 D424 K425Q50-D422 PolarHBondContact O-N 3.01Å; K52-D422 VanDerWaalsContact CE-CG 3.41Å; K52-D422 WeakPolarHBondContact CE-OD2 3.46Å; K52-D422 IonicContact NZ-OD1 3.88Å; K52-D422 PolarHBondContact NZ-OD1 3.48Å; K52-D422 IonicContact NZ-OD2 3.83Å; K52-D422 PolarHBondContact NZ-OD2 3.33Å; D422-D424 VanDerWaalsContact C-N 3.25Å; D422-D424 PolarHBondContact O-N 3.36Å; D422-D424 PolarHBondContact OD1-N 3.06Å; D422-K425 HydrophobicContact CB-CB 4.18Å; D422-K425 HydrophobicContact CB-CG 4.01Å; D422-K425 PolarHBondContact O-N 3.35Å; D422-K425 VanDerWaalsContact O-N 3.17Å
423Q93.2Very high94.8Very high115 Ų11560.1 Ų60.154%0.53731%0.306SS..G310 helixtrans-68.5-27.4-176.7-61.9-63.4-3100111.6E418 K425 V426E418-Q423 PolarHBondContact OE1-NE2 3.08Å; Q423-K425 PolarHBondContact O-N 3.07Å; Q423-V426 WeakPolarHBondContact O-CG2 3.39Å; Q423-V426 PolarHBondContact O-N 3.04Å
424D93.6Very high94.8Very high157 Ų15762.8 Ų62.884%0.8432%0.319SS*.G310 helixtrans-71.4-9176.1-65.2-24.6000113.2D422D422-D424 VanDerWaalsContact C-N 3.25Å; D422-D424 PolarHBondContact O-N 3.36Å; D422-D424 PolarHBondContact OD1-N 3.06Å
425K95.1Very high94.8Very high92 Ų9265.5 Ų65.540%0.433%0.331SS..G310 helixtrans-106.6-3.3-179.3-68.5-71.4-167.4168.30113.9E49 Q50 D422 Q423 T427E49-K425 HydrophobicContact CB-CD 4.45Å; E49-K425 IonicContact OE2-NZ 3.58Å; E49-K425 PolarHBondContact OE2-NZ 3.26Å; Q50-K425 HydrophobicContact CB-CB 4.48Å; Q50-K425 HydrophobicContact CG-CB 3.79Å; Q50-K425 VanDerWaalsContact CG-O 3.22Å; Q50-K425 WeakPolarHBondContact CG-O 3.42Å; Q50-K425 PolarHBondContact NE2-O 3.34Å; D422-K425 HydrophobicContact CB-CB 4.18Å; D422-K425 HydrophobicContact CB-CG 4.01Å; D422-K425 PolarHBondContact O-N 3.35Å; D422-K425 VanDerWaalsContact O-N 3.17Å; Q423-K425 PolarHBondContact O-N 3.07Å; K425-T427 PolarHBondContact O-N 2.95Å
426V94.6Very high94.9Very high35 Ų3563 Ų6321%0.21231%0.31CS..  trans-65.5123.1-179.4179.60000109.9Q423 D430 V431 M434Q423-V426 WeakPolarHBondContact O-CG2 3.39Å; Q423-V426 PolarHBondContact O-N 3.04Å; V426-D430 HydrophobicContact CG1-CB 4Å; V426-V431 HydrophobicContact CG1-CG2 3.79Å; V426-M434 HydrophobicContact CG1-CE 4.15Å
427T95.5Very high94.8Very high49 Ų4964.1 Ų64.130%0.30131%0.312SS..  trans-89.1162.7178.3790000111.7R46 K425 Y429 D430 V431R46-T427 HydrophobicContact CG-CG2 3.88Å; K425-T427 PolarHBondContact O-N 2.95Å; T427-Y429 PolarHBondContact O-N 3.43Å; T427-Y429 VanDerWaalsContact O-N 3.15Å; T427-Y429 PolarHBondContact OG1-N 3.3Å; T427-D430 WeakPolarHBondContact CA-OD2 3.49Å; T427-D430 VanDerWaalsContact CB-OD2 3.25Å; T427-D430 WeakPolarHBondContact CB-OD2 3.32Å; T427-D430 PolarHBondContact N-OD2 3.34Å; T427-D430 PolarHBondContact O-N 2.87Å; T427-D430 PolarHBondContact OG1-OD2 3.08Å; T427-V431 PolarHBondContact O-N 3.12Å; T427-V431 VanDerWaalsContact O-N 3.14Å
428Q95.2Very high94.8Very high110 Ų11075.3 Ų75.351%0.51435%0.354SS..Hα-helixtrans-51.5-36.8174.4-171.4-176.710.300113.1A121 V431 L432A121-Q428 PolarHBondContact O-NE2 3.46Å; Q428-V431 PolarHBondContact O-N 2.7Å; Q428-L432 HydrophobicContact CG-CD1 4.18Å; Q428-L432 VanDerWaalsContact O-CG 3.31Å; Q428-L432 WeakPolarHBondContact O-CG 3.46Å; Q428-L432 PolarHBondContact O-N 2.9Å
429Y96.5Very high94.9Very high57 Ų5775.3 Ų75.322%0.22436%0.364CS..Hα-helixtrans-69.7-34.8178.3-70.3-72.3000112.6Y6 R123 L124 T427 L432 H433Y6-Y429 HydrophobicContact CD2-CG 4.23Å; R123-Y429 HydrophobicContact CB-CE1 4.19Å; R123-Y429 PolarHBondContact NE-OH 2.9Å; R123-Y429 PolarHBondContact NH2-OH 2.98Å; L124-Y429 HydrophobicContact CD1-CD1 4.21Å; L124-Y429 WeakPolarHBondContact CD1-O 3.38Å; L124-Y429 HydrophobicContact CD2-CD1 3.86Å; L124-Y429 HydrophobicContact CD2-CE1 4.41Å; L124-Y429 HydrophobicContact CG-CD1 3.85Å; L124-Y429 HydrophobicContact CG-CE1 4.48Å; T427-Y429 PolarHBondContact O-N 3.43Å; T427-Y429 VanDerWaalsContact O-N 3.15Å; T427-Y429 PolarHBondContact OG1-N 3.3Å; Y429-L432 PolarHBondContact O-N 3.33Å; Y429-H433 VanDerWaalsContact O-CB 3.27Å; Y429-H433 WeakPolarHBondContact O-CB 3.48Å; Y429-H433 PolarHBondContact O-N 3.19Å
430D95.6Very high94.8Very high0 Ų070.1 Ų70.10%035%0.354CS..Hα-helixtrans-68.6-38.5175.9-47.7-78.9000110.8Y6 R46 Q50 V426 T427 H433 M434Y6-D430 WeakPolarHBondContact CE2-OD1 3.42Å; Y6-D430 PolarHBondContact OH-OD1 2.91Å; R46-D430 IonicContact CZ-OD1 2.8Å; R46-D430 IonicContact NH1-OD1 3.92Å; R46-D430 PolarHBondContact NH1-OD1 3.49Å; Q50-D430 PolarHBondContact NE2-OD2 2.92Å; Q50-D430 PolarHBondContact OE1-OD1 3.47Å; V426-D430 HydrophobicContact CG1-CB 4Å; T427-D430 WeakPolarHBondContact CA-OD2 3.49Å; T427-D430 VanDerWaalsContact CB-OD2 3.25Å; T427-D430 WeakPolarHBondContact CB-OD2 3.32Å; T427-D430 PolarHBondContact N-OD2 3.34Å; T427-D430 PolarHBondContact O-N 2.87Å; T427-D430 PolarHBondContact OG1-OD2 3.08Å; D430-H433 PolarHBondContact O-N 3.24Å; D430-M434 WeakPolarHBondContact O-CB 3.48Å; D430-M434 WeakPolarHBondContact O-CE 3.44Å; D430-M434 VanDerWaalsContact O-CG 3.27Å; D430-M434 WeakPolarHBondContact O-CG 3.48Å; D430-M434 PolarHBondContact O-N 2.77Å
431V96.1Very high94.9Very high79 Ų7969.4 Ų69.448%0.47935%0.347SS..Hα-helixtrans-61.9-49.7173.5-1790000111.2V426 T427 Q428 H433 M434 E435V426-V431 HydrophobicContact CG1-CG2 3.79Å; T427-V431 PolarHBondContact O-N 3.12Å; T427-V431 VanDerWaalsContact O-N 3.14Å; Q428-V431 PolarHBondContact O-N 2.7Å; V431-H433 VanDerWaalsContact C-N 3.35Å; V431-H433 PolarHBondContact O-N 3.48Å; V431-M434 PolarHBondContact O-N 2.73Å; V431-E435 PolarHBondContact O-N 3.45Å
432L96.5Very high94.8Very high26 Ų2669.6 Ų69.614%0.13635%0.35CS..Hα-helixtrans-60.6-42.1177.8-72.4167.8000112D122 L124 Q428 Y429 E435 N436D122-L432 HydrophobicContact CB-CD1 4.04Å; D122-L432 HydrophobicContact CB-CD2 4.21Å; L124-L432 HydrophobicContact CD1-CB 3.95Å; Q428-L432 HydrophobicContact CG-CD1 4.18Å; Q428-L432 VanDerWaalsContact O-CG 3.31Å; Q428-L432 WeakPolarHBondContact O-CG 3.46Å; Q428-L432 PolarHBondContact O-N 2.9Å; Y429-L432 PolarHBondContact O-N 3.33Å; L432-E435 PolarHBondContact O-N 3.04Å; L432-N436 PolarHBondContact O-N 3.22Å
433H96.2Very high94.9Very high20 Ų2068.8 Ų68.89%0.09335%0.345CS..Hα-helixtrans-67.2-39.7177.6-176.476.8000112.3Y6 E89 L124 Y429 D430 V431 N436 K437Y6-H433 HydrophobicContact CE1-CB 3.6Å; Y6-H433 AromaticContact CE1-CG 3.56Å; Y6-H433 AromaticContact CE1-ND1 3.81Å; E89-H433 IonicContact OE1-CE1 3.97Å; E89-H433 IonicContact OE1-CG 3.62Å; E89-H433 IonicContact OE1-ND1 2.74Å; E89-H433 PolarHBondContact OE1-ND1 2.96Å; E89-H433 IonicContact OE2-ND1 3.67Å; L124-H433 HydrophobicContact CD1-CB 3.86Å; Y429-H433 VanDerWaalsContact O-CB 3.27Å; Y429-H433 WeakPolarHBondContact O-CB 3.48Å; Y429-H433 PolarHBondContact O-N 3.19Å; D430-H433 PolarHBondContact O-N 3.24Å; V431-H433 VanDerWaalsContact C-N 3.35Å; V431-H433 PolarHBondContact O-N 3.48Å; H433-N436 WeakPolarHBondContact O-CB 3.36Å; H433-N436 PolarHBondContact O-N 3.18Å; H433-K437 VanDerWaalsContact NE2-CE 3.33Å; H433-K437 WeakPolarHBondContact NE2-CE 3.38Å; H433-K437 PolarHBondContact O-N 3.23Å
434M94.2Very high94.9Very high75 Ų7563.6 Ų63.637%0.36932%0.32SS..Hα-helixtrans-66.2-36.5173.7-72.9-173.3-66.700112.2R421 V426 D430 V431 N436 R438R421-M434 PolarHBondContact NH1-SD 3.17Å; V426-M434 HydrophobicContact CG1-CE 4.15Å; D430-M434 WeakPolarHBondContact O-CB 3.48Å; D430-M434 WeakPolarHBondContact O-CE 3.44Å; D430-M434 VanDerWaalsContact O-CG 3.27Å; D430-M434 WeakPolarHBondContact O-CG 3.48Å; D430-M434 PolarHBondContact O-N 2.77Å; V431-M434 PolarHBondContact O-N 2.73Å; M434-N436 VanDerWaalsContact C-N 3.34Å; M434-R438 WeakPolarHBondContact O-CB 3.43Å; M434-R438 PolarHBondContact O-N 3.16Å
435E95.9Very high95Very high101 Ų10160.2 Ų60.247%0.47230%0.298SS..Hα-helixtrans-64.9-37.8171.5-161.1-151.4106.700111.7V431 L432 A439 R441V431-E435 PolarHBondContact O-N 3.45Å; L432-E435 PolarHBondContact O-N 3.04Å; E435-A439 WeakPolarHBondContact O-CB 3.37Å; E435-A439 PolarHBondContact O-N 3.44Å; E435-A439 VanDerWaalsContact O-N 3.12Å; E435-R441 VanDerWaalsContact C-NH2 3.29Å; E435-R441 PolarHBondContact O-NH2 2.92Å; E435-R441 IonicContact OE1-CZ 2.86Å; E435-R441 IonicContact OE1-NH1 2.71Å; E435-R441 PolarHBondContact OE1-NH1 2.9Å; E435-R441 IonicContact OE1-NH2 2.57Å; E435-R441 PolarHBondContact OE1-NH2 3.18Å
436N96.1Very high95Very high4 Ų456.2 Ų56.22%0.02128%0.282CS..Hα-helixtrans-63.5-54.3174.1-78.1-23.8000111.3T125 L432 H433 M434 R438 A439 G440 R441T125-N436 WeakPolarHBondContact CG2-OD1 3.06Å; T125-N436 PolarHBondContact OG1-ND2 3.14Å; T125-N436 PolarHBondContact OG1-OD1 2.86Å; L432-N436 PolarHBondContact O-N 3.22Å; H433-N436 WeakPolarHBondContact O-CB 3.36Å; H433-N436 PolarHBondContact O-N 3.18Å; M434-N436 VanDerWaalsContact C-N 3.34Å; N436-R438 PolarHBondContact O-N 3.43Å; N436-A439 CarbonylContact O-C 3.33Å; N436-A439 PolarHBondContact O-N 3.18Å; N436-A439 VanDerWaalsContact O-N 3.15Å; N436-G440 PolarHBondContact O-N 3.48Å; N436-R441 HydrophobicContact CB-CB 4.12Å; N436-R441 WeakPolarHBondContact O-CB 3.49Å; N436-R441 PolarHBondContact O-N 3.49Å; N436-R441 PolarHBondContact OD1-NE 3Å; N436-R441 PolarHBondContact OD1-NH1 3.05Å
437K92.6Very high95Very high80 Ų8055.1 Ų55.135%0.34828%0.275SS..Hα-helixtrans-54.6-48174.9-81.2-167.5172.7-175.50112.3E10 H433 A439 G440E10-K437 IonicContact OE1-NZ 2.75Å; E10-K437 PolarHBondContact OE1-NZ 3.03Å; H433-K437 VanDerWaalsContact NE2-CE 3.33Å; H433-K437 WeakPolarHBondContact NE2-CE 3.38Å; H433-K437 PolarHBondContact O-N 3.23Å; K437-A439 PolarHBondContact O-N 2.83Å; K437-G440 PolarHBondContact O-N 2.89Å
438R93.9Very high94.9Very high235 Ų23556.7 Ų56.789%0.88728%0.275SS*.Hα-helixtrans-60.8-31.4-179.9-176.1177.6178.9-171.50.5113.3M434 N436 G440M434-R438 WeakPolarHBondContact O-CB 3.43Å; M434-R438 PolarHBondContact O-N 3.16Å; N436-R438 PolarHBondContact O-N 3.43Å; R438-G440 VanDerWaalsContact C-N 3.33Å
439A94.6Very high94.9Very high62 Ų6257.7 Ų57.751%0.51228%0.279SS..THydrogen-bonded Turntrans-88.76175.800000113.6E435 N436 K437 R441E435-A439 WeakPolarHBondContact O-CB 3.37Å; E435-A439 PolarHBondContact O-N 3.44Å; E435-A439 VanDerWaalsContact O-N 3.12Å; N436-A439 CarbonylContact O-C 3.33Å; N436-A439 PolarHBondContact O-N 3.18Å; N436-A439 VanDerWaalsContact O-N 3.15Å; K437-A439 PolarHBondContact O-N 2.83Å; A439-R441 HydrophobicContact CB-CG 4.33Å; A439-R441 PolarHBondContact O-N 2.93Å
440G93.4Very high94.8Very high44 Ų4455.8 Ų55.845%0.45427%0.273SS..THydrogen-bonded Turntrans67.320.1-176.500000114.4N436 K437 R438 K445N436-G440 PolarHBondContact O-N 3.48Å; K437-G440 PolarHBondContact O-N 2.89Å; R438-G440 VanDerWaalsContact C-N 3.33Å; G440-K445 WeakPolarHBondContact O-CD 3.39Å
441R94.5Very high94.8Very high58 Ų5857.5 Ų57.522%0.21928%0.279CS..  trans-85.4129.4178.8-73.3173.9-74.5-175.2-4.3110.9E435 N436 A439E435-R441 VanDerWaalsContact C-NH2 3.29Å; E435-R441 PolarHBondContact O-NH2 2.92Å; E435-R441 IonicContact OE1-CZ 2.86Å; E435-R441 IonicContact OE1-NH1 2.71Å; E435-R441 PolarHBondContact OE1-NH1 2.9Å; E435-R441 IonicContact OE1-NH2 2.57Å; E435-R441 PolarHBondContact OE1-NH2 3.18Å; N436-R441 HydrophobicContact CB-CB 4.12Å; N436-R441 WeakPolarHBondContact O-CB 3.49Å; N436-R441 PolarHBondContact O-N 3.49Å; N436-R441 PolarHBondContact OD1-NE 3Å; N436-R441 PolarHBondContact OD1-NH1 3.05Å; A439-R441 HydrophobicContact CB-CG 4.33Å; A439-R441 PolarHBondContact O-N 2.93Å
442D93.7Very high94.6Very high25 Ų2556.5 Ų56.513%0.13428%0.279CS..  trans-121.6177.3161.865.979.3000110.2T398 Y444 K445 T446T398-D442 HydrophobicContact CG2-CB 4.19Å; D442-Y444 PolarHBondContact O-N 2.84Å; D442-Y444 WeakPolarHBondContact OD1-CA 3.35Å; D442-Y444 PolarHBondContact OD1-N 3.34Å; D442-K445 PolarHBondContact OD1-N 2.91Å; D442-K445 VanDerWaalsContact OD2-CB 3.31Å; D442-K445 WeakPolarHBondContact OD2-CB 3.5Å; D442-K445 WeakPolarHBondContact OD2-CD 3.33Å; D442-K445 WeakPolarHBondContact OD2-CE 3.27Å; D442-K445 WeakPolarHBondContact OD2-CG 3.34Å; D442-K445 IonicContact OD2-NZ 3.81Å; D442-K445 PolarHBondContact OD2-NZ 2.74Å; D442-T446 VanDerWaalsContact O-CB 3.23Å; D442-T446 WeakPolarHBondContact O-CB 3.47Å; D442-T446 PolarHBondContact O-N 2.74Å; D442-T446 PolarHBondContact O-OG1 3.33Å
443K95.5Very high94.3Very high21 Ų2157.2 Ų57.29%0.09129%0.294CS..Hα-helixtrans-53-45.6179.5-171.3169.5-170.5167.90113.5Q86 D87 L88 Y91 L447Q86-K443 PolarHBondContact O-NZ 2.7Å; D87-K443 WeakPolarHBondContact O-CB 3.48Å; D87-K443 VanDerWaalsContact O-CD 3.29Å; D87-K443 WeakPolarHBondContact O-CD 3.34Å; L88-K443 PolarHBondContact O-NZ 2.83Å; Y91-K443 PolarHBondContact O-NZ 3.25Å; K443-L447 HydrophobicContact CG-CD1 4.23Å; K443-L447 WeakPolarHBondContact O-CB 3.23Å; K443-L447 WeakPolarHBondContact O-CD1 3.35Å; K443-L447 WeakPolarHBondContact O-CG 3.3Å; K443-L447 PolarHBondContact O-N 3.41Å
444Y94.5Very high94.2Very high5 Ų561.2 Ų61.22%0.0232%0.315CS..Hα-helixtrans-83.6-37.5-175.5-55.2-61.6000112.8D87 L113 R396 T398 D442 T446 L447 R448D87-Y444 HydrophobicContact CB-CE2 4.39Å; D87-Y444 WeakPolarHBondContact OD1-CE2 3.37Å; D87-Y444 PolarHBondContact OD1-OH 3.45Å; L113-Y444 HydrophobicContact CD1-CE1 4.28Å; R396-Y444 HydrophobicContact CB-CD1 4.06Å; R396-Y444 HydrophobicContact CB-CE1 4.47Å; R396-Y444 HydrophobicContact CB-CG 4.13Å; R396-Y444 HydrophobicContact CG-CD1 4.02Å; R396-Y444 HydrophobicContact CG-CD2 3.99Å; R396-Y444 HydrophobicContact CG-CE1 4.01Å; R396-Y444 HydrophobicContact CG-CE2 3.94Å; R396-Y444 HydrophobicContact CG-CG 4.05Å; R396-Y444 PolarHBondContact NE-OH 3.47Å; R396-Y444 VanDerWaalsContact NE-OH 3.1Å; R396-Y444 PolarHBondContact NH2-OH 2.86Å; R396-Y444 WeakPolarHBondContact O-CB 3.28Å; T398-Y444 HydrophobicContact CG2-CD2 3.94Å; T398-Y444 HydrophobicContact CG2-CE2 4.07Å; D442-Y444 PolarHBondContact O-N 2.84Å; D442-Y444 WeakPolarHBondContact OD1-CA 3.35Å; D442-Y444 PolarHBondContact OD1-N 3.34Å; Y444-T446 VanDerWaalsContact C-N 3.32Å; Y444-T446 PolarHBondContact O-N 3.07Å; Y444-L447 HydrophobicContact CD1-CD1 4.27Å; Y444-L447 PolarHBondContact O-N 2.93Å; Y444-R448 WeakPolarHBondContact O-CB 3.44Å; Y444-R448 WeakPolarHBondContact O-CG 3.38Å; Y444-R448 PolarHBondContact O-N 3.39Å
445K94.3Very high94.2Very high86 Ų8658.3 Ų58.337%0.37430%0.302SS..Hα-helixtrans-60.1-43.4169.3-75.9-178.6-159.892.50111.1E401 G440 D442 R448 Q449E401-K445 IonicContact OE1-NZ 3.24Å; E401-K445 PolarHBondContact OE1-NZ 3.17Å; G440-K445 WeakPolarHBondContact O-CD 3.39Å; D442-K445 PolarHBondContact OD1-N 2.91Å; D442-K445 VanDerWaalsContact OD2-CB 3.31Å; D442-K445 WeakPolarHBondContact OD2-CB 3.5Å; D442-K445 WeakPolarHBondContact OD2-CD 3.33Å; D442-K445 WeakPolarHBondContact OD2-CE 3.27Å; D442-K445 WeakPolarHBondContact OD2-CG 3.34Å; D442-K445 IonicContact OD2-NZ 3.81Å; D442-K445 PolarHBondContact OD2-NZ 2.74Å; K445-R448 PolarHBondContact O-N 3.05Å; K445-Q449 WeakPolarHBondContact O-CB 3.39Å; K445-Q449 PolarHBondContact O-N 3.21Å
446T95.7Very high94.2Very high9 Ų955.1 Ų55.16%0.05529%0.287CS..Hα-helixtrans-64.8-47177.2-530000111.1T125 P126 D442 Y444 R448 Q449 I450T125-T446 HydrophobicContact CG2-CG2 3.98Å; P126-T446 HydrophobicContact CG-CG2 4.27Å; D442-T446 VanDerWaalsContact O-CB 3.23Å; D442-T446 WeakPolarHBondContact O-CB 3.47Å; D442-T446 PolarHBondContact O-N 2.74Å; D442-T446 PolarHBondContact O-OG1 3.33Å; Y444-T446 VanDerWaalsContact C-N 3.32Å; Y444-T446 PolarHBondContact O-N 3.07Å; T446-R448 VanDerWaalsContact C-N 3.33Å; T446-R448 PolarHBondContact O-N 3.05Å; T446-Q449 PolarHBondContact O-N 3.3Å; T446-Q449 VanDerWaalsContact O-N 3.12Å; T446-I450 HydrophobicContact CG2-CG2 4.36Å; T446-I450 WeakPolarHBondContact O-CG1 3.22Å; T446-I450 PolarHBondContact O-N 3.36Å
447L94.8Very high94.2Very high12 Ų1262 Ų626%0.06331%0.313CS..Hα-helixtrans-58.7-40175.6-78168.1000113L113 N116 K443 Y444 I450 R451L113-L447 HydrophobicContact CD1-CD1 3.76Å; N116-L447 WeakPolarHBondContact OD1-CD2 3.29Å; K443-L447 HydrophobicContact CG-CD1 4.23Å; K443-L447 WeakPolarHBondContact O-CB 3.23Å; K443-L447 WeakPolarHBondContact O-CD1 3.35Å; K443-L447 WeakPolarHBondContact O-CG 3.3Å; K443-L447 PolarHBondContact O-N 3.41Å; Y444-L447 HydrophobicContact CD1-CD1 4.27Å; Y444-L447 PolarHBondContact O-N 2.93Å; L447-I450 HydrophobicContact CD2-CD1 4.4Å; L447-R451 WeakPolarHBondContact O-CB 3.5Å; L447-R451 VanDerWaalsContact O-CD 3.3Å; L447-R451 WeakPolarHBondContact O-CD 3.42Å; L447-R451 WeakPolarHBondContact O-CG 3.5Å; L447-R451 PolarHBondContact O-N 3Å
448R93.9Very high94.4Very high81 Ų8158.4 Ų58.431%0.30630%0.297SS..Hα-helixtrans-60.1-49171.8-77.8-178.1-78.9-86.82111.4I394 R396 Y444 K445 T446 R451I394-R448 HydrophobicContact CG2-CG 4.42Å; I394-R448 VanDerWaalsContact O-CD 3.26Å; I394-R448 WeakPolarHBondContact O-CD 3.27Å; I394-R448 PolarHBondContact O-NH1 3.16Å; R396-R448 PolarHBondContact O-NH1 2.96Å; Y444-R448 WeakPolarHBondContact O-CB 3.44Å; Y444-R448 WeakPolarHBondContact O-CG 3.38Å; Y444-R448 PolarHBondContact O-N 3.39Å; K445-R448 PolarHBondContact O-N 3.05Å; T446-R448 VanDerWaalsContact C-N 3.33Å; T446-R448 PolarHBondContact O-N 3.05Å; R448-R451 PolarHBondContact O-N 2.99Å
449Q94.7Very high94.6Very high131 Ų13147.3 Ų47.361%0.61226%0.255SS*.Hα-helixtrans-61.2-46.8-176.5-174.11793.400112.5K445 T446 R451 A452K445-Q449 WeakPolarHBondContact O-CB 3.39Å; K445-Q449 PolarHBondContact O-N 3.21Å; T446-Q449 PolarHBondContact O-N 3.3Å; T446-Q449 VanDerWaalsContact O-N 3.12Å; Q449-R451 VanDerWaalsContact C-N 3.31Å; Q449-R451 PolarHBondContact O-N 2.91Å; Q449-A452 VanDerWaalsContact O-CB 3.28Å; Q449-A452 WeakPolarHBondContact O-CB 3.44Å; Q449-A452 PolarHBondContact O-N 2.97Å
450I95Very high94.6Very high18 Ų1846.7 Ų46.79%0.09224%0.244CC..Hα-helixtrans-80.4-8.5-174.970.5179.1000114.7P126 K127 G129 T446 L447 R458P126-I450 HydrophobicContact CB-CD1 3.58Å; P126-I450 HydrophobicContact CG-CD1 3.61Å; P126-I450 WeakPolarHBondContact O-CG2 3.34Å; K127-I450 WeakPolarHBondContact O-CG2 3.5Å; G129-I450 PolarHBondContact N-O 3.29Å; T446-I450 HydrophobicContact CG2-CG2 4.36Å; T446-I450 WeakPolarHBondContact O-CG1 3.22Å; T446-I450 PolarHBondContact O-N 3.36Å; L447-I450 HydrophobicContact CD2-CD1 4.4Å; I450-R458 WeakPolarHBondContact O-CD 3.41Å
451R94.8Very high94.8Very high35 Ų3548.3 Ų48.313%0.13224%0.239CC..THydrogen-bonded Turntrans-95-3.6172.9-68.6173.1-177.2-155.4-8.7112.1L113 L447 R448 Q449 R458L113-R451 PolarHBondContact O-NH1 3.38Å; L113-R451 PolarHBondContact O-NH2 2.92Å; L447-R451 WeakPolarHBondContact O-CB 3.5Å; L447-R451 VanDerWaalsContact O-CD 3.3Å; L447-R451 WeakPolarHBondContact O-CD 3.42Å; L447-R451 WeakPolarHBondContact O-CG 3.5Å; L447-R451 PolarHBondContact O-N 3Å; R448-R451 PolarHBondContact O-N 2.99Å; Q449-R451 VanDerWaalsContact C-N 3.31Å; Q449-R451 PolarHBondContact O-N 2.91Å; R451-R458 VanDerWaalsContact O-CZ 3.32Å; R451-R458 PolarHBondContact O-NE 3.07Å; R451-R458 VanDerWaalsContact O-NE 3.14Å; R451-R458 PolarHBondContact O-NH2 3.26Å
452A91.6Very high94.9Very high58 Ų5845.6 Ų45.648%0.47923%0.229SC..  trans-65.9144.9-179.900000112.9Q449Q449-A452 VanDerWaalsContact O-CB 3.28Å; Q449-A452 WeakPolarHBondContact O-CB 3.44Å; Q449-A452 PolarHBondContact O-N 2.97Å
453G91.1Very high95Very high42 Ų4245.4 Ų45.443%0.43323%0.227SC..SBendtrans79.5171.4-175.400000113.5R458G453-R458 PolarHBondContact O-NE 2.93Å; G453-R458 VanDerWaalsContact O-NE 3.16Å; G453-R458 PolarHBondContact O-NH2 2.85Å
454N92.8Very high95Very high103 Ų10349.6 Ų49.655%0.55125%0.251SS*.  trans-71.8161.1-177.366.315.3000112.8Q456 R457 R458N454-Q456 VanDerWaalsContact C-N 3.3Å; N454-Q456 PolarHBondContact O-N 2.92Å; N454-R457 PolarHBondContact O-N 3Å; N454-R457 WeakPolarHBondContact OD1-CB 3.37Å; N454-R457 PolarHBondContact OD1-N 3.27Å; N454-R458 PolarHBondContact O-N 3.28Å
455T94.7Very high95Very high14 Ų1450.4 Ų50.49%0.08626%0.255CS..Hα-helixtrans-58.9-39.9-177.7-45.90000111.9F130 E134 P149 R457 R458 I459F130-T455 HydrophobicContact CD1-CG2 3.97Å; F130-T455 HydrophobicContact CE1-CG2 3.93Å; E134-T455 VanDerWaalsContact CD-OG1 3.31Å; E134-T455 WeakPolarHBondContact OE2-CB 3.46Å; E134-T455 WeakPolarHBondContact OE2-CG2 3.43Å; E134-T455 PolarHBondContact OE2-OG1 2.78Å; P149-T455 HydrophobicContact CB-CG2 3.86Å; T455-R457 PolarHBondContact O-N 2.92Å; T455-R458 PolarHBondContact O-N 2.91Å; T455-I459 HydrophobicContact CG2-CD1 4.15Å; T455-I459 WeakPolarHBondContact O-CG1 3.44Å; T455-I459 PolarHBondContact O-N 3.08Å
456Q96.2Very high94.5Very high34 Ų3453.8 Ų53.816%0.15928%0.283CS..Hα-helixtrans-55.4-49.7175.1-175.350.147.400112.8S154 R155 N454 R458 I459 D460S154-Q456 WeakPolarHBondContact OG-CB 3.4Å; S154-Q456 PolarHBondContact OG-N 3.28Å; S154-Q456 VanDerWaalsContact OG-N 3.1Å; R155-Q456 VanDerWaalsContact NE-NE2 3.17Å; N454-Q456 VanDerWaalsContact C-N 3.3Å; N454-Q456 PolarHBondContact O-N 2.92Å; Q456-R458 VanDerWaalsContact C-N 3.29Å; Q456-R458 PolarHBondContact O-N 3.48Å; Q456-I459 PolarHBondContact O-N 3.23Å; Q456-D460 PolarHBondContact NE2-OD1 3.28Å; Q456-D460 PolarHBondContact NE2-OD2 2.66Å; Q456-D460 VanDerWaalsContact O-CG 3.26Å; Q456-D460 PolarHBondContact O-N 2.9Å; Q456-D460 VanDerWaalsContact O-OD2 3.14Å
457R96.3Very high94.5Very high148 Ų14856.1 Ų56.156%0.55829%0.294SS*.Hα-helixtrans-57.9-40.8177.6176.4-178.6174.3176.8-0.2112N454 T455 D460 Q461N454-R457 PolarHBondContact O-N 3Å; N454-R457 WeakPolarHBondContact OD1-CB 3.37Å; N454-R457 PolarHBondContact OD1-N 3.27Å; T455-R457 PolarHBondContact O-N 2.92Å; R457-D460 PolarHBondContact O-N 3.33Å; R457-Q461 WeakPolarHBondContact O-CG 3.45Å; R457-Q461 PolarHBondContact O-N 3.4Å; R457-Q461 PolarHBondContact O-OE1 2.98Å
458R97Very high94.5Very high5 Ų558.4 Ų58.42%0.01931%0.306CS..Hα-helixtrans-70.6-33.4179.6-77.7-179.7-84.3121.4-3.8112.5I128 G129 F130 E134 I450 R451 G453 N454 T455 Q456 Q461 F462I128-R458 HydrophobicContact CG2-CB 3.81Å; I128-R458 HydrophobicContact CG2-CG 4.16Å; G129-R458 WeakPolarHBondContact O-CD 3.49Å; G129-R458 PolarHBondContact O-NH1 3.44Å; F130-R458 HydrophobicContact CE1-CB 3.62Å; F130-R458 HydrophobicContact CZ-CB 3.85Å; E134-R458 VanDerWaalsContact CD-NH2 3.32Å; E134-R458 IonicContact OE1-CZ 2.72Å; E134-R458 IonicContact OE1-NH1 3.47Å; E134-R458 PolarHBondContact OE1-NH1 3.24Å; E134-R458 IonicContact OE1-NH2 2.68Å; E134-R458 PolarHBondContact OE1-NH2 2.99Å; E134-R458 IonicContact OE2-CZ 3.79Å; E134-R458 IonicContact OE2-NH1 2.69Å; E134-R458 PolarHBondContact OE2-NH1 3.13Å; E134-R458 IonicContact OE2-NH2 3.19Å; E134-R458 PolarHBondContact OE2-NH2 3.32Å; E134-R458 VanDerWaalsContact OE2-NH2 3.15Å; I450-R458 WeakPolarHBondContact O-CD 3.41Å; R451-R458 VanDerWaalsContact O-CZ 3.32Å; R451-R458 PolarHBondContact O-NE 3.07Å; R451-R458 VanDerWaalsContact O-NE 3.14Å; R451-R458 PolarHBondContact O-NH2 3.26Å; G453-R458 PolarHBondContact O-NE 2.93Å; G453-R458 VanDerWaalsContact O-NE 3.16Å; G453-R458 PolarHBondContact O-NH2 2.85Å; N454-R458 PolarHBondContact O-N 3.28Å; T455-R458 PolarHBondContact O-N 2.91Å; Q456-R458 VanDerWaalsContact C-N 3.29Å; Q456-R458 PolarHBondContact O-N 3.48Å; R458-Q461 PolarHBondContact O-N 3.06Å; R458-F462 PolarHBondContact O-N 3.05Å; R458-F462 VanDerWaalsContact O-N 3.12Å
459I96.9Very high94.5Very high3 Ų357.1 Ų57.12%0.01531%0.306CS..Hα-helixtrans-67.8-39.5169.5-65.7172.8000111F130 R155 F157 T455 Q456 Q461 F462 E463F130-I459 HydrophobicContact CE1-CG1 3.93Å; F130-I459 HydrophobicContact CZ-CG1 3.87Å; R155-I459 WeakPolarHBondContact O-CD1 3.23Å; F157-I459 HydrophobicContact CB-CD1 3.84Å; F157-I459 HydrophobicContact CB-CG1 4.01Å; T455-I459 HydrophobicContact CG2-CD1 4.15Å; T455-I459 WeakPolarHBondContact O-CG1 3.44Å; T455-I459 PolarHBondContact O-N 3.08Å; Q456-I459 PolarHBondContact O-N 3.23Å; I459-Q461 VanDerWaalsContact C-N 3.34Å; I459-Q461 PolarHBondContact O-N 3.25Å; I459-F462 WeakPolarHBondContact O-CB 3.04Å; I459-F462 PolarHBondContact O-N 3.4Å; I459-E463 PolarHBondContact O-N 2.89Å; I459-E463 VanDerWaalsContact O-N 3.14Å
460D95.8Very high94.5Very high49 Ų4952.8 Ų52.826%0.26229%0.288SS..Hα-helixtrans-68.6-31.6176.6-66.3-33.3000112.7R155 Q456 R457 N464R155-D460 IonicContact CZ-OD1 3.16Å; R155-D460 IonicContact NE-OD1 3.31Å; R155-D460 IonicContact NH2-OD1 3.42Å; R155-D460 PolarHBondContact NH2-OD1 3.16Å; Q456-D460 PolarHBondContact NE2-OD1 3.28Å; Q456-D460 PolarHBondContact NE2-OD2 2.66Å; Q456-D460 VanDerWaalsContact O-CG 3.26Å; Q456-D460 PolarHBondContact O-N 2.9Å; Q456-D460 VanDerWaalsContact O-OD2 3.14Å; R457-D460 PolarHBondContact O-N 3.33Å; D460-N464 WeakPolarHBondContact O-CB 3.3Å; D460-N464 PolarHBondContact O-N 3.06Å; D460-N464 PolarHBondContact O-ND2 2.6Å
461Q96.5Very high94.4Very high78 Ų7854.9 Ų54.936%0.36430%0.3SS..Hα-helixtrans-65.9-43.7169.7-73.7169.8-61.100111.1I128 R457 R458 I459 E463 N464 M465I128-Q461 HydrophobicContact CD1-CB 3.69Å; I128-Q461 HydrophobicContact CG1-CB 4.35Å; R457-Q461 WeakPolarHBondContact O-CG 3.45Å; R457-Q461 PolarHBondContact O-N 3.4Å; R457-Q461 PolarHBondContact O-OE1 2.98Å; R458-Q461 PolarHBondContact O-N 3.06Å; I459-Q461 VanDerWaalsContact C-N 3.34Å; I459-Q461 PolarHBondContact O-N 3.25Å; Q461-E463 PolarHBondContact O-N 3.28Å; Q461-N464 CarbonylContact O-C 3.51Å; Q461-N464 WeakPolarHBondContact O-CA 3.35Å; Q461-N464 PolarHBondContact O-N 3.4Å; Q461-M465 WeakPolarHBondContact O-CG 3.42Å; Q461-M465 PolarHBondContact O-N 3.18Å
462F97.3Very high94.4Very high0 Ų056.3 Ų56.30%031%0.312CS..Hα-helixtrans-60.4-45.3-180169.3-96.2000113.2I98 N100 L106 I117 I128 F157 I158 F159 R458 I459 N464 M465I98-F462 HydrophobicContact CD1-CE2 3.95Å; I98-F462 HydrophobicContact CD1-CZ 4.21Å; N100-F462 HydrophobicContact CB-CD1 4.04Å; N100-F462 HydrophobicContact CB-CE1 3.38Å; N100-F462 HydrophobicContact CB-CE2 4.17Å; N100-F462 HydrophobicContact CB-CZ 3.45Å; N100-F462 VanDerWaalsContact CB-CZ 3.45Å; N100-F462 PolarHBondContact ND2-O 3Å; N100-F462 VanDerWaalsContact ND2-O 3.09Å; L106-F462 HydrophobicContact CD1-CD2 3.99Å; L106-F462 HydrophobicContact CD1-CE2 3.55Å; L106-F462 HydrophobicContact CD1-CZ 4.28Å; I117-F462 HydrophobicContact CD1-CD2 4.32Å; I117-F462 HydrophobicContact CD1-CE2 4.27Å; I117-F462 HydrophobicContact CG1-CD2 4.05Å; I117-F462 HydrophobicContact CG1-CE2 4.47Å; I117-F462 HydrophobicContact CG2-CD2 3.98Å; I117-F462 HydrophobicContact CG2-CE2 4.16Å; I128-F462 VanDerWaalsContact CD1-CA 3.46Å; I128-F462 HydrophobicContact CD1-CB 3.81Å; F157-F462 HydrophobicContact CD2-CD1 4.08Å; F157-F462 HydrophobicContact CD2-CE1 4.32Å; F157-F462 HydrophobicContact CD2-CG 4.4Å; F157-F462 HydrophobicContact CE2-CB 4.48Å; F157-F462 AromaticContact CE2-CD1 3.61Å; F157-F462 HydrophobicContact CE2-CD1 3.61Å; F157-F462 AromaticContact CE2-CD2 3.86Å; F157-F462 HydrophobicContact CE2-CD2 3.86Å; F157-F462 AromaticContact CE2-CE1 3.68Å; F157-F462 HydrophobicContact CE2-CE1 3.68Å; F157-F462 AromaticContact CE2-CE2 3.92Å; F157-F462 HydrophobicContact CE2-CE2 3.92Å; F157-F462 AromaticContact CE2-CG 3.7Å; F157-F462 HydrophobicContact CE2-CG 3.7Å; F157-F462 AromaticContact CE2-CZ 3.83Å; F157-F462 HydrophobicContact CE2-CZ 3.83Å; F157-F462 HydrophobicContact CZ-CD2 4.43Å; F157-F462 HydrophobicContact CZ-CE2 4.31Å; F157-F462 HydrophobicContact CZ-CZ 4.43Å; I158-F462 WeakPolarHBondContact O-CE1 3.47Å; F159-F462 HydrophobicContact CB-CE1 4.4Å; F159-F462 HydrophobicContact CB-CZ 3.82Å; R458-F462 PolarHBondContact O-N 3.05Å; R458-F462 VanDerWaalsContact O-N 3.12Å; I459-F462 WeakPolarHBondContact O-CB 3.04Å; I459-F462 PolarHBondContact O-N 3.4Å; F462-N464 PolarHBondContact O-N 2.68Å; F462-M465 PolarHBondContact O-N 2.75Å
463E95.5Very high94.6Very high22 Ų2256.1 Ų56.110%0.10330%0.3CS..THydrogen-bonded Turntrans-71.6-6.6176.3-58.5-69.9-166.500112.8K101 K102 I459 Q461K101-E463 VanDerWaalsContact CB-OE2 3.31Å; K101-E463 WeakPolarHBondContact CB-OE2 3.49Å; K101-E463 WeakPolarHBondContact CD-OE1 3.41Å; K101-E463 WeakPolarHBondContact CG-OE1 3.48Å; K101-E463 WeakPolarHBondContact CG-OE2 3.38Å; K101-E463 PolarHBondContact N-OE2 3.45Å; K101-E463 IonicContact NZ-OE1 3.27Å; K101-E463 PolarHBondContact NZ-OE1 3.41Å; K102-E463 VanDerWaalsContact CD-O 3.32Å; K102-E463 WeakPolarHBondContact CD-O 3.45Å; K102-E463 WeakPolarHBondContact CE-O 3.47Å; K102-E463 PolarHBondContact NZ-O 3.03Å; I459-E463 PolarHBondContact O-N 2.89Å; I459-E463 VanDerWaalsContact O-N 3.14Å; Q461-E463 PolarHBondContact O-N 3.28Å
464N95.5Very high94.9Very high108 Ų10857.2 Ų57.258%0.57829%0.289SS*.THydrogen-bonded Turntrans-110.1-1.2175.1-72.7-53.7000114.9K102 D460 Q461 F462K102-N464 PolarHBondContact NZ-OD1 3.03Å; D460-N464 WeakPolarHBondContact O-CB 3.3Å; D460-N464 PolarHBondContact O-N 3.06Å; D460-N464 PolarHBondContact O-ND2 2.6Å; Q461-N464 CarbonylContact O-C 3.51Å; Q461-N464 WeakPolarHBondContact O-CA 3.35Å; Q461-N464 PolarHBondContact O-N 3.4Å; F462-N464 PolarHBondContact O-N 2.68Å
465M95.2Very high95.1Very high22 Ų2253.4 Ų53.411%0.10827%0.268CS..  trans-62.9148.9161.9-58.9-175.478.100109.9N100 S104 L106 I117 E119 K127 I128 Q461 F462N100-M465 PolarHBondContact ND2-O 3.01Å; S104-M465 PolarHBondContact OG-O 3.18Å; S104-M465 VanDerWaalsContact OG-O 3.09Å; L106-M465 HydrophobicContact CD1-CB 4.15Å; L106-M465 HydrophobicContact CD1-SD 4.08Å; L106-M465 HydrophobicContact CD2-CB 4.12Å; L106-M465 HydrophobicContact CD2-CE 3.68Å; L106-M465 HydrophobicContact CD2-SD 4.01Å; I117-M465 HydrophobicContact CG2-CE 4.45Å; I117-M465 HydrophobicContact CG2-SD 3.85Å; E119-M465 HydrophobicContact CG-CE 3.6Å; K127-M465 HydrophobicContact CB-CE 4.09Å; K127-M465 HydrophobicContact CG-CE 4.04Å; I128-M465 HydrophobicContact CD1-CG 4.21Å; I128-M465 HydrophobicContact CD1-SD 3.65Å; I128-M465 HydrophobicContact CG1-SD 4.32Å; Q461-M465 WeakPolarHBondContact O-CG 3.42Å; Q461-M465 PolarHBondContact O-N 3.18Å; F462-M465 PolarHBondContact O-N 2.75Å
466V84Confident95.1Very high158 Ų15857 Ų5796%0.95828%0.284SS*.  trans-116.30-176.8178.80000109.6S104S104-V466 WeakPolarHBondContact CA-OXT 3.21Å; S104-V466 WeakPolarHBondContact CB-OXT 3.43Å; S104-V466 VanDerWaalsContact OG-C 3.28Å; S104-V466 VanDerWaalsContact OG-CA 3.29Å; S104-V466 WeakPolarHBondContact OG-CA 3.49Å; S104-V466 PolarHBondContact OG-OXT 3.14Å

Retrieved 466 of 466 residues in 131.6 ms (Link to these results)