A0A077ZKC7_TRITR Loading...

Histone deacetylase

AlphaFold DB , UniProt , Accession A0A077ZKC7, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 387 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M37.5Very low67.6Low227 Ų22790.7 Ų90.7100%1.11851%0.508SS*.  091.40-66173.8-169.700108S3M1-S3 PolarHBondContact O-N 3.21Å; M1-S3 VanDerWaalsContact O-N 3.17Å
2S32.3Very low70.2Confident78 Ų7883.2 Ų83.255%0.54547%0.466SS..  trans-71.1104166.8157.50000105.6Q293S2-Q293 PolarHBondContact O-NE2 3.11Å
3S39.4Very low72.4Confident62 Ų6276.8 Ų76.843%0.43443%0.43SS..  trans-67.4136.1-177.550.30000109.9M1 N5M1-S3 PolarHBondContact O-N 3.21Å; M1-S3 VanDerWaalsContact O-N 3.17Å; S3-N5 VanDerWaalsContact CB-ND2 3.32Å; S3-N5 WeakPolarHBondContact CB-ND2 3.43Å; S3-N5 VanDerWaalsContact CB-OD1 3.23Å; S3-N5 WeakPolarHBondContact CB-OD1 3.29Å; S3-N5 PolarHBondContact O-N 3.2Å; S3-N5 VanDerWaalsContact OG-CB 3.25Å; S3-N5 WeakPolarHBondContact OG-CB 3.39Å; S3-N5 PolarHBondContact OG-ND2 2.9Å
4T50.6Low74.3Confident33 Ų3371.3 Ų71.320%0.20240%0.399CS..  trans-66.131.7165.942.10000111.7G6 L7 Q293 L296 T325T4-G6 PolarHBondContact O-N 2.99Å; T4-L7 PolarHBondContact O-N 3.16Å; T4-Q293 HydrophobicContact CG2-CG 4.28Å; T4-L296 HydrophobicContact CG2-CB 4.39Å; T4-L296 HydrophobicContact CG2-CD1 4.47Å; T4-T325 PolarHBondContact OG1-O 3.09Å
5N53.5Low75.9Confident140 Ų14066.5 Ų66.575%0.74937%0.373SS*.THydrogen-bonded Turntrans-67.812.8-158.8-99.95.7000116.2S3S3-N5 VanDerWaalsContact CB-ND2 3.32Å; S3-N5 WeakPolarHBondContact CB-ND2 3.43Å; S3-N5 VanDerWaalsContact CB-OD1 3.23Å; S3-N5 WeakPolarHBondContact CB-OD1 3.29Å; S3-N5 PolarHBondContact O-N 3.2Å; S3-N5 VanDerWaalsContact OG-CB 3.25Å; S3-N5 WeakPolarHBondContact OG-CB 3.39Å; S3-N5 PolarHBondContact OG-ND2 2.9Å
6G72.3Confident77.3Confident54 Ų5465.1 Ų65.156%0.55736%0.36SS*.THydrogen-bonded Turntrans-115.7-15.2-17700000115.5T4 T8T4-G6 PolarHBondContact O-N 2.99Å; G6-T8 PolarHBondContact O-N 3.25Å
7L86.7Confident78.6Confident42 Ų4261.6 Ų61.622%0.2234%0.341CS..  trans-81.3118.7-175.4-62.2179.3000110.3T4 D11 V12 K134 V135 A326T4-L7 PolarHBondContact O-N 3.16Å; L7-D11 HydrophobicContact CB-CB 4.28Å; L7-D11 HydrophobicContact CD2-CB 3.71Å; L7-V12 HydrophobicContact CB-CG2 4.18Å; L7-V12 HydrophobicContact CD1-CG2 4.16Å; L7-K134 HydrophobicContact CD2-CB 4.01Å; L7-K134 HydrophobicContact CD2-CD 3.71Å; L7-K134 HydrophobicContact CD2-CG 4.48Å; L7-V135 HydrophobicContact CD1-CG2 3.82Å; L7-A326 WeakPolarHBondContact CD1-O 3.45Å
8T90.1Very high79.6Confident77 Ų7763.2 Ų63.247%0.47236%0.355SS..  trans-89.8170.9171.671.50000110.2G6 N10 D11G6-T8 PolarHBondContact O-N 3.25Å; T8-N10 PolarHBondContact O-N 3.36Å; T8-N10 VanDerWaalsContact O-N 3.08Å; T8-N10 PolarHBondContact OG1-N 3.49Å; T8-D11 WeakPolarHBondContact CA-OD2 3.37Å; T8-D11 WeakPolarHBondContact CB-OD2 3.37Å; T8-D11 PolarHBondContact N-OD2 3.47Å; T8-D11 WeakPolarHBondContact O-CB 3.45Å; T8-D11 PolarHBondContact O-N 3.02Å; T8-D11 PolarHBondContact OG1-OD2 3.4Å
9R90.9Very high80.5Confident146 Ų14664.7 Ų64.755%0.55136%0.359SS*.G310 helixtrans-50.4-35.6173.6178.6-179.8-178.7-157-0.3113.5D11 G48 H49 V50 K51R9-D11 VanDerWaalsContact C-N 3.32Å; R9-G48 WeakPolarHBondContact CD-O 3.22Å; R9-H49 WeakPolarHBondContact CA-O 3.46Å; R9-V50 PolarHBondContact NE-O 3.17Å; R9-K51 PolarHBondContact O-N 3.2Å
10N93.8Very high81.4Confident116 Ų11661.6 Ų61.662%0.6234%0.341SS*.G310 helixtrans-80.7-14.3-177.5-66.5-27.9000112.7T8T8-N10 PolarHBondContact O-N 3.36Å; T8-N10 VanDerWaalsContact O-N 3.08Å; T8-N10 PolarHBondContact OG1-N 3.49Å
11D97.1Very high82.2Confident23 Ų2359 Ų5912%0.12333%0.328CS..G310 helixtrans-84.3-13.2179.1-64.5-72.7000113.1L7 T8 R9 K134 V135L7-D11 HydrophobicContact CB-CB 4.28Å; L7-D11 HydrophobicContact CD2-CB 3.71Å; T8-D11 WeakPolarHBondContact CA-OD2 3.37Å; T8-D11 WeakPolarHBondContact CB-OD2 3.37Å; T8-D11 PolarHBondContact N-OD2 3.47Å; T8-D11 WeakPolarHBondContact O-CB 3.45Å; T8-D11 PolarHBondContact O-N 3.02Å; T8-D11 PolarHBondContact OG1-OD2 3.4Å; R9-D11 VanDerWaalsContact C-N 3.32Å; D11-K134 HydrophobicContact CB-CB 4.32Å; D11-K134 HydrophobicContact CB-CD 4.21Å; D11-K134 HydrophobicContact CB-CG 4.33Å; D11-K134 PolarHBondContact O-N 3Å; D11-K134 WeakPolarHBondContact OD1-CD 3.49Å; D11-K134 WeakPolarHBondContact OD1-CE 3.47Å; D11-K134 IonicContact OD1-NZ 2.8Å; D11-K134 PolarHBondContact OD1-NZ 2.75Å; D11-K134 IonicContact OD2-NZ 2.71Å; D11-V135 PolarHBondContact O-N 3.2Å
12V98.4Very high85Confident0 Ų054.9 Ų54.90%031%0.305CS..EExtended strand (participates in β ladder)trans-124.1119.7-175-1720000110.5L7 V50 K51 V135 I137 V327L7-V12 HydrophobicContact CB-CG2 4.18Å; L7-V12 HydrophobicContact CD1-CG2 4.16Å; V12-V50 HydrophobicContact CB-CG1 3.94Å; V12-V50 HydrophobicContact CG1-CB 4.47Å; V12-V50 HydrophobicContact CG1-CG1 3.65Å; V12-V50 WeakPolarHBondContact O-CA 3.34Å; V12-V50 WeakPolarHBondContact O-CB 3.37Å; V12-K51 PolarHBondContact O-N 2.77Å; V12-V135 CarbonylContact C-O 3.58Å; V12-V135 VanDerWaalsContact CA-O 3.28Å; V12-V135 WeakPolarHBondContact CA-O 3.25Å; V12-V135 HydrophobicContact CG1-CB 4.25Å; V12-V135 HydrophobicContact CG1-CG1 4.35Å; V12-V135 HydrophobicContact CG2-CB 4.24Å; V12-I137 HydrophobicContact CG1-CD1 3.78Å; V12-I137 HydrophobicContact CG1-CG1 4.36Å; V12-V327 HydrophobicContact CB-CG1 4.38Å; V12-V327 HydrophobicContact CG1-CG1 4.28Å; V12-V327 HydrophobicContact CG2-CG1 4.28Å
13A98.7Very high88Confident0 Ų052.5 Ų52.50%029%0.286CS..EExtended strand (participates in β ladder)trans-105.3140.5172.800000112.5K51 F53 L127 V133 V135 S136 I137A13-K51 CarbonylContact C-O 3.53Å; A13-K51 WeakPolarHBondContact CA-O 3.29Å; A13-K51 HydrophobicContact CB-CB 4.48Å; A13-F53 HydrophobicContact CB-CD1 4.16Å; A13-F53 HydrophobicContact CB-CE1 4.27Å; A13-L127 HydrophobicContact CB-CD1 3.85Å; A13-V133 HydrophobicContact CB-CB 4.48Å; A13-V133 HydrophobicContact CB-CG1 3.79Å; A13-V133 HydrophobicContact CB-CG2 4.31Å; A13-V135 PolarHBondContact N-O 3.39Å; A13-S136 CarbonylContact O-C 3.55Å; A13-S136 WeakPolarHBondContact O-CA 3.22Å; A13-I137 PolarHBondContact O-N 2.93Å
14L98.8Very high90.8Very high0 Ų049.6 Ų49.60%027%0.266CS..EExtended strand (participates in β ladder)trans-121.4122.1175.117764.1000109.8Y16 F38 F47 V50 K51 V52 F53 I137 L323L14-Y16 PolarHBondContact O-N 3.28Å; L14-F38 HydrophobicContact CD1-CE1 4.32Å; L14-F38 HydrophobicContact CD2-CE1 4.32Å; L14-F38 HydrophobicContact CG-CE1 4.47Å; L14-F47 HydrophobicContact CD2-CD1 4.16Å; L14-F47 HydrophobicContact CD2-CE1 3.65Å; L14-F47 HydrophobicContact CD2-CZ 4.04Å; L14-V50 HydrophobicContact CB-CB 4.43Å; L14-V50 HydrophobicContact CB-CG2 3.9Å; L14-V50 HydrophobicContact CD2-CG2 4.27Å; L14-K51 PolarHBondContact N-O 2.72Å; L14-V52 WeakPolarHBondContact O-CA 3.4Å; L14-F53 WeakPolarHBondContact O-CD1 3.24Å; L14-F53 PolarHBondContact O-N 3.28Å; L14-I137 HydrophobicContact CD1-CB 3.85Å; L14-I137 HydrophobicContact CD1-CG2 3.73Å; L14-L323 HydrophobicContact CD2-CD2 4.25Å
15A98.8Very high92.9Very high0 Ų049.7 Ų49.70%027%0.266CS..EExtended strand (participates in β ladder)trans-71.6115.3170.600000109.4F53 A120 I137 N138A15-F53 HydrophobicContact CB-CE1 3.75Å; A15-F53 HydrophobicContact CB-CE2 4.2Å; A15-F53 HydrophobicContact CB-CZ 3.54Å; A15-A120 HydrophobicContact CB-CB 3.99Å; A15-I137 PolarHBondContact N-O 3.22Å; A15-N138 HydrophobicContact CB-CB 4.3Å
16Y98.7Very high94.9Very high44 Ų4445.9 Ų45.917%0.17325%0.248CC..  trans-155.2138.7175.9165.9-94.5000111.6L14 F38 F47 V52 F53L14-Y16 PolarHBondContact O-N 3.28Å; Y16-F38 HydrophobicContact CD2-CB 4.03Å; Y16-F38 AromaticContact CD2-CD1 3.52Å; Y16-F38 HydrophobicContact CD2-CD1 3.52Å; Y16-F38 AromaticContact CD2-CD2 3.53Å; Y16-F38 HydrophobicContact CD2-CD2 3.53Å; Y16-F38 AromaticContact CD2-CE1 3.7Å; Y16-F38 HydrophobicContact CD2-CE1 3.7Å; Y16-F38 AromaticContact CD2-CE2 3.72Å; Y16-F38 HydrophobicContact CD2-CE2 3.72Å; Y16-F38 AromaticContact CD2-CG 3.42Å; Y16-F38 HydrophobicContact CD2-CG 3.42Å; Y16-F38 VanDerWaalsContact CD2-CG 3.42Å; Y16-F38 AromaticContact CD2-CZ 3.8Å; Y16-F38 HydrophobicContact CD2-CZ 3.8Å; Y16-F38 HydrophobicContact CE2-CB 3.74Å; Y16-F38 HydrophobicContact CE2-CD1 4.14Å; Y16-F38 AromaticContact CE2-CD2 3.77Å; Y16-F38 HydrophobicContact CE2-CD2 3.77Å; Y16-F38 HydrophobicContact CE2-CE2 4.37Å; Y16-F38 AromaticContact CE2-CG 3.64Å; Y16-F38 HydrophobicContact CE2-CG 3.64Å; Y16-F38 HydrophobicContact CG-CD1 4.27Å; Y16-F38 HydrophobicContact CG-CE1 4.24Å; Y16-F47 AromaticContact CD1-CE2 3.54Å; Y16-F47 HydrophobicContact CD1-CE2 3.54Å; Y16-F47 HydrophobicContact CD1-CZ 4.09Å; Y16-F47 HydrophobicContact CD2-CE2 4.3Å; Y16-F47 HydrophobicContact CD2-CZ 4.05Å; Y16-F47 AromaticContact CE1-CE2 3.72Å; Y16-F47 HydrophobicContact CE1-CE2 3.72Å; Y16-F47 HydrophobicContact CE1-CZ 4.38Å; Y16-F47 HydrophobicContact CE2-CE2 4.45Å; Y16-F47 HydrophobicContact CE2-CZ 4.35Å; Y16-F47 AromaticContact CG-CE2 3.83Å; Y16-F47 HydrophobicContact CG-CE2 3.83Å; Y16-F47 AromaticContact CG-CZ 3.89Å; Y16-F47 HydrophobicContact CG-CZ 3.89Å; Y16-V52 HydrophobicContact CD1-CG1 3.83Å; Y16-V52 HydrophobicContact CG-CG1 4.32Å; Y16-F53 PolarHBondContact N-O 3.37Å; Y16-F53 CarbonylContact O-C 3.57Å
17S98.2Very high95.9Very high5 Ų544 Ų444%0.03523%0.226CC..  trans-153.3157160.467.50000109.8Q19 L20 S21S17-Q19 PolarHBondContact O-N 3.21Å; S17-L20 WeakPolarHBondContact O-CB 3.3Å; S17-L20 PolarHBondContact O-N 3.2Å; S17-L20 VanDerWaalsContact O-N 3.09Å; S17-L20 PolarHBondContact OG-N 3.33Å; S17-L20 VanDerWaalsContact OG-N 3.1Å; S17-S21 PolarHBondContact O-N 3.33Å; S17-S21 VanDerWaalsContact O-N 3.1Å
18P97.4Very high96.1Very high90 Ų9050.4 Ų50.458%0.58425%0.254SS*.Hα-helixtrans-53.2-40172.9-27.635.5000112.6S21 E22P18-S21 WeakPolarHBondContact O-CB 3.25Å; P18-S21 PolarHBondContact O-N 2.92Å; P18-E22 WeakPolarHBondContact O-CB 3.36Å; P18-E22 PolarHBondContact O-N 3.05Å
19Q97.3Very high96Very high93 Ų9349.5 Ų49.544%0.43525%0.249SC..Hα-helixtrans-62.8-41.2177-176.9-177.2-1.400112.9S17 S21 L23 L116S17-Q19 PolarHBondContact O-N 3.21Å; Q19-S21 VanDerWaalsContact C-N 3.32Å; Q19-L23 HydrophobicContact CG-CD1 4.2Å; Q19-L23 WeakPolarHBondContact O-CB 3.19Å; Q19-L23 PolarHBondContact O-N 2.95Å; Q19-L116 HydrophobicContact CG-CD2 4.3Å
20L98.1Very high96.1Very high1 Ų142.8 Ų42.81%0.00522%0.223CC..Hα-helixtrans-61.2-44.9174.4174.167.6000110.4S17 C24 P55 L116 V117 C140S17-L20 WeakPolarHBondContact O-CB 3.3Å; S17-L20 PolarHBondContact O-N 3.2Å; S17-L20 VanDerWaalsContact O-N 3.09Å; S17-L20 PolarHBondContact OG-N 3.33Å; S17-L20 VanDerWaalsContact OG-N 3.1Å; L20-C24 WeakPolarHBondContact O-CB 3.3Å; L20-C24 PolarHBondContact O-N 3.4Å; L20-C24 PolarHBondContact O-SG 3.37Å; L20-P55 HydrophobicContact CB-CG 4.44Å; L20-P55 HydrophobicContact CD2-CG 4.1Å; L20-L116 HydrophobicContact CB-CD2 4.04Å; L20-L116 HydrophobicContact CD1-CD2 4.08Å; L20-L116 HydrophobicContact CD1-CG 3.98Å; L20-V117 HydrophobicContact CD1-CG2 4.04Å; L20-C140 HydrophobicContact CD1-CB 4.25Å; L20-C140 HydrophobicContact CD2-CB 4.39Å
21S97.2Very high96.2Very high8 Ų843.9 Ų43.96%0.05622%0.223CC..Hα-helixtrans-62.7-47.3179.7-149.60000111.6S17 P18 Q19 L23 C24 D25 S35S17-S21 PolarHBondContact O-N 3.33Å; S17-S21 VanDerWaalsContact O-N 3.1Å; P18-S21 WeakPolarHBondContact O-CB 3.25Å; P18-S21 PolarHBondContact O-N 2.92Å; Q19-S21 VanDerWaalsContact C-N 3.32Å; S21-L23 PolarHBondContact O-N 2.95Å; S21-C24 PolarHBondContact O-N 3.16Å; S21-D25 WeakPolarHBondContact O-CB 3.18Å; S21-D25 VanDerWaalsContact O-CG 3.31Å; S21-D25 PolarHBondContact O-N 3.41Å; S21-S35 WeakPolarHBondContact OG-CA 3.45Å; S21-S35 WeakPolarHBondContact OG-CB 3.43Å; S21-S35 PolarHBondContact OG-N 3.03Å; S21-S35 PolarHBondContact OG-OG 3.33Å
22E96.5Very high96.1Very high140 Ų14048.6 Ų48.665%0.65424%0.242SC*.Hα-helixtrans-61.3-44.7178.8-174.9176.8-169.300112.1P18 D25 T26P18-E22 WeakPolarHBondContact O-CB 3.36Å; P18-E22 PolarHBondContact O-N 3.05Å; E22-D25 PolarHBondContact O-N 3.41Å; E22-T26 WeakPolarHBondContact O-CG2 3.38Å; E22-T26 PolarHBondContact O-N 2.71Å
23L96.5Very high96Very high28 Ų2848.8 Ų48.815%0.14724%0.243CC..Hα-helixtrans-67-37.7176-80169.5000112.7Q19 S21 D25 T26 A112 L116Q19-L23 HydrophobicContact CG-CD1 4.2Å; Q19-L23 WeakPolarHBondContact O-CB 3.19Å; Q19-L23 PolarHBondContact O-N 2.95Å; S21-L23 PolarHBondContact O-N 2.95Å; L23-D25 VanDerWaalsContact C-N 3.28Å; L23-D25 PolarHBondContact O-N 2.84Å; L23-T26 PolarHBondContact O-N 3.47Å; L23-T26 PolarHBondContact O-OG1 2.93Å; L23-A112 HydrophobicContact CD1-CB 4.41Å; L23-A112 HydrophobicContact CD2-CB 4.06Å; L23-L116 HydrophobicContact CD1-CB 4.43Å; L23-L116 HydrophobicContact CD1-CD2 3.6Å
24C97.2Very high95.9Very high2 Ų248.9 Ų48.91%0.01424%0.244CC..Hα-helixtrans-67.4-32.6175.3-66.50000112.1L20 S21 T26 V27 T34 Y113L20-C24 WeakPolarHBondContact O-CB 3.3Å; L20-C24 PolarHBondContact O-N 3.4Å; L20-C24 PolarHBondContact O-SG 3.37Å; S21-C24 PolarHBondContact O-N 3.16Å; C24-T26 PolarHBondContact O-N 3.09Å; C24-V27 PolarHBondContact O-N 3.15Å; C24-T34 HydrophobicContact CB-CG2 3.76Å; C24-T34 WeakPolarHBondContact CB-OG1 3.44Å; C24-Y113 HydrophobicContact CB-CE2 4.26Å
25D95.8Very high95.9Very high34 Ų3450 Ų5018%0.18225%0.252CS..THydrogen-bonded Turntrans-73.2-10.6179.1-79.18.1000113.3S21 E22 L23 V27 K32 S35S21-D25 WeakPolarHBondContact O-CB 3.18Å; S21-D25 VanDerWaalsContact O-CG 3.31Å; S21-D25 PolarHBondContact O-N 3.41Å; E22-D25 PolarHBondContact O-N 3.41Å; L23-D25 VanDerWaalsContact C-N 3.28Å; L23-D25 PolarHBondContact O-N 2.84Å; D25-V27 VanDerWaalsContact C-N 3.26Å; D25-K32 HydrophobicContact CB-CG 4.14Å; D25-K32 VanDerWaalsContact OD1-CA 3.28Å; D25-K32 WeakPolarHBondContact OD1-CA 3.41Å; D25-S35 PolarHBondContact OD1-N 3.14Å; D25-S35 PolarHBondContact OD1-OG 2.77Å; D25-S35 WeakPolarHBondContact OD2-CB 3.5Å; D25-S35 PolarHBondContact OD2-OG 2.8Å
26T94.4Very high95.8Very high61 Ų6150.3 Ų50.337%0.37425%0.253SS..THydrogen-bonded Turntrans-75.3-17171.3710000112.7E22 L23 C24 E28 S109E22-T26 WeakPolarHBondContact O-CG2 3.38Å; E22-T26 PolarHBondContact O-N 2.71Å; L23-T26 PolarHBondContact O-N 3.47Å; L23-T26 PolarHBondContact O-OG1 2.93Å; C24-T26 PolarHBondContact O-N 3.09Å; T26-E28 PolarHBondContact O-N 2.83Å; T26-S109 WeakPolarHBondContact CB-OG 3.39Å; T26-S109 PolarHBondContact OG1-OG 2.77Å
27V93.8Very high95.8Very high15 Ų1548.2 Ų48.29%0.09125%0.245CC..  trans-78.1104.9177-169.70000109.1C24 D25 T29 L30 F107 Y113C24-V27 PolarHBondContact O-N 3.15Å; D25-V27 VanDerWaalsContact C-N 3.26Å; V27-T29 VanDerWaalsContact C-N 3.31Å; V27-T29 PolarHBondContact O-N 2.98Å; V27-L30 HydrophobicContact CB-CB 4.38Å; V27-L30 HydrophobicContact CB-CD1 3.97Å; V27-L30 HydrophobicContact CB-CG 3.94Å; V27-L30 HydrophobicContact CG1-CD1 4.08Å; V27-L30 HydrophobicContact CG1-CG 3.78Å; V27-L30 HydrophobicContact CG2-CD1 4.43Å; V27-L30 PolarHBondContact O-N 3.37Å; V27-F107 HydrophobicContact CG2-CE2 4.24Å; V27-F107 HydrophobicContact CG2-CZ 3.8Å; V27-Y113 HydrophobicContact CG2-CD1 4.04Å; V27-Y113 HydrophobicContact CG2-CD2 3.94Å; V27-Y113 HydrophobicContact CG2-CE1 3.83Å; V27-Y113 HydrophobicContact CG2-CE2 3.72Å; V27-Y113 HydrophobicContact CG2-CG 4.08Å
28E90.5Very high95.9Very high176 Ų17648 Ų4882%0.82224%0.243SC*.G310 helixtrans-57.7-41.4-171.8-174.1173.9-173.600113T26 L30 K31T26-E28 PolarHBondContact O-N 2.83Å; E28-L30 PolarHBondContact O-N 2.69Å; E28-L30 VanDerWaalsContact O-N 3.11Å; E28-K31 WeakPolarHBondContact O-CG 2.91Å; E28-K31 PolarHBondContact O-N 2.9Å; E28-K31 VanDerWaalsContact O-N 3.08Å
29T88.6Confident95.9Very high58 Ų5844.4 Ų44.436%0.35622%0.22SC..G310 helixtrans-60.4-23.9179.655.20000112.9V27 F154V27-T29 VanDerWaalsContact C-N 3.31Å; V27-T29 PolarHBondContact O-N 2.98Å; T29-F154 HydrophobicContact CG2-CD1 4.49Å; T29-F154 HydrophobicContact CG2-CE1 4.38Å
30L93.2Very high96Very high4 Ų440 Ų402%0.02120%0.2CC..G310 helixtrans-89.9-9-178.9-54-170.9000113.6V27 E28 K32 R33 W143V27-L30 HydrophobicContact CB-CB 4.38Å; V27-L30 HydrophobicContact CB-CD1 3.97Å; V27-L30 HydrophobicContact CB-CG 3.94Å; V27-L30 HydrophobicContact CG1-CD1 4.08Å; V27-L30 HydrophobicContact CG1-CG 3.78Å; V27-L30 HydrophobicContact CG2-CD1 4.43Å; V27-L30 PolarHBondContact O-N 3.37Å; E28-L30 PolarHBondContact O-N 2.69Å; E28-L30 VanDerWaalsContact O-N 3.11Å; L30-K32 VanDerWaalsContact C-N 3.27Å; L30-K32 PolarHBondContact O-N 3.31Å; L30-K32 VanDerWaalsContact O-N 3.09Å; L30-R33 HydrophobicContact CB-CG 4.13Å; L30-R33 VanDerWaalsContact O-CB 3.24Å; L30-R33 WeakPolarHBondContact O-CB 3.12Å; L30-R33 PolarHBondContact O-N 3.28Å; L30-W143 HydrophobicContact CD1-CH2 3.94Å; L30-W143 HydrophobicContact CD1-CZ2 3.92Å; L30-W143 HydrophobicContact CD2-CH2 3.94Å
31K94.4Very high96Very high139 Ų13940 Ų4060%0.60420%0.2SC*.THydrogen-bonded Turntrans45.646.3171.1-60.6176.9-176.91710114.1E28 R33 P312E28-K31 WeakPolarHBondContact O-CG 2.91Å; E28-K31 PolarHBondContact O-N 2.9Å; E28-K31 VanDerWaalsContact O-N 3.08Å; K31-R33 PolarHBondContact O-N 3.14Å; K31-P312 HydrophobicContact CB-CG 3.7Å; K31-P312 HydrophobicContact CD-CG 4.43Å
32K95Very high96.1Very high123 Ų12343.9 Ų43.954%0.53522%0.217SC..THydrogen-bonded Turntrans58.725.3-178.4-51.8-174.7176.3-176.90115.4D25 L30 T34 M36D25-K32 HydrophobicContact CB-CG 4.14Å; D25-K32 VanDerWaalsContact OD1-CA 3.28Å; D25-K32 WeakPolarHBondContact OD1-CA 3.41Å; L30-K32 VanDerWaalsContact C-N 3.27Å; L30-K32 PolarHBondContact O-N 3.31Å; L30-K32 VanDerWaalsContact O-N 3.09Å; K32-T34 PolarHBondContact O-N 2.84Å; K32-M36 WeakPolarHBondContact O-CB 3.36Å; K32-M36 PolarHBondContact O-N 2.84Å
33R96.7Very high96.1Very high3 Ų339 Ų391%0.01120%0.201CC..Hα-helixtrans-56.4-32.7178.978.3-175.9-175.3172.72.3112.2L30 K31 T37 G307 G309 P312 F315L30-R33 HydrophobicContact CB-CG 4.13Å; L30-R33 VanDerWaalsContact O-CB 3.24Å; L30-R33 WeakPolarHBondContact O-CB 3.12Å; L30-R33 PolarHBondContact O-N 3.28Å; K31-R33 PolarHBondContact O-N 3.14Å; R33-T37 WeakPolarHBondContact O-CB 3.36Å; R33-T37 PolarHBondContact O-N 2.96Å; R33-T37 PolarHBondContact O-OG1 3.24Å; R33-G307 PolarHBondContact NH1-O 3.41Å; R33-G307 PolarHBondContact NH2-O 3.45Å; R33-G309 PolarHBondContact NH1-O 2.98Å; R33-P312 HydrophobicContact CB-CB 3.84Å; R33-P312 HydrophobicContact CB-CG 4.36Å; R33-F315 HydrophobicContact CB-CD1 4.21Å; R33-F315 HydrophobicContact CB-CG 4.46Å; R33-F315 HydrophobicContact CG-CD1 4.1Å; R33-F315 HydrophobicContact CG-CE1 4.24Å; R33-F315 HydrophobicContact CG-CG 4.42Å
34T97.1Very high96.2Very high3 Ų339.2 Ų39.22%0.01820%0.2CC..Hα-helixtrans-68.5-55.3-176.2-61.20000111.6C24 K32 M36 T37 F38 C140C24-T34 HydrophobicContact CB-CG2 3.76Å; C24-T34 WeakPolarHBondContact CB-OG1 3.44Å; K32-T34 PolarHBondContact O-N 2.84Å; T34-M36 VanDerWaalsContact C-N 3.26Å; T34-M36 PolarHBondContact O-N 3.46Å; T34-T37 PolarHBondContact O-N 3.47Å; T34-T37 VanDerWaalsContact O-N 3.15Å; T34-F38 HydrophobicContact CG2-CD2 3.65Å; T34-F38 HydrophobicContact CG2-CE2 3.41Å; T34-F38 VanDerWaalsContact CG2-CE2 3.41Å; T34-F38 WeakPolarHBondContact O-CD2 3.27Å; T34-F38 PolarHBondContact O-N 2.89Å; T34-C140 WeakPolarHBondContact CG2-SG 3.39Å
35S97.8Very high96.3Very high24 Ų2440.8 Ų40.817%0.16822%0.217CC..Hα-helixtrans-61.3-36.9176.6-66.20000112.5S21 D25 T37 S39S21-S35 WeakPolarHBondContact OG-CA 3.45Å; S21-S35 WeakPolarHBondContact OG-CB 3.43Å; S21-S35 PolarHBondContact OG-N 3.03Å; S21-S35 PolarHBondContact OG-OG 3.33Å; D25-S35 PolarHBondContact OD1-N 3.14Å; D25-S35 PolarHBondContact OD1-OG 2.77Å; D25-S35 WeakPolarHBondContact OD2-CB 3.5Å; D25-S35 PolarHBondContact OD2-OG 2.8Å; S35-T37 PolarHBondContact O-N 3.45Å; S35-S39 WeakPolarHBondContact O-CB 3.28Å; S35-S39 PolarHBondContact O-N 3.24Å
36M98.2Very high96.4Very high5 Ų539.3 Ų39.33%0.02521%0.208CC..Hα-helixtrans-59.1-46.9174.3-175-175.6-52.800111.8K32 T34 S39 L40 P312 V313 A316 F340 L343 Y344K32-M36 WeakPolarHBondContact O-CB 3.36Å; K32-M36 PolarHBondContact O-N 2.84Å; T34-M36 VanDerWaalsContact C-N 3.26Å; T34-M36 PolarHBondContact O-N 3.46Å; M36-S39 PolarHBondContact O-N 3.3Å; M36-L40 WeakPolarHBondContact O-CB 3.35Å; M36-L40 PolarHBondContact O-N 2.99Å; M36-P312 HydrophobicContact CE-CB 3.77Å; M36-P312 HydrophobicContact SD-CB 4.14Å; M36-V313 HydrophobicContact CE-CG2 4.43Å; M36-V313 HydrophobicContact SD-CB 4.5Å; M36-V313 HydrophobicContact SD-CG2 4Å; M36-A316 HydrophobicContact CG-CB 3.9Å; M36-A316 HydrophobicContact SD-CB 4.05Å; M36-F340 HydrophobicContact CB-CD1 4.24Å; M36-F340 HydrophobicContact CB-CD2 4.25Å; M36-F340 HydrophobicContact CB-CE1 4.49Å; M36-F340 HydrophobicContact CB-CG 4.11Å; M36-F340 HydrophobicContact CE-CD1 4.34Å; M36-F340 HydrophobicContact CG-CB 3.97Å; M36-F340 HydrophobicContact CG-CD1 4.44Å; M36-F340 HydrophobicContact CG-CD2 4.46Å; M36-F340 HydrophobicContact CG-CG 4.06Å; M36-L343 HydrophobicContact CE-CD1 3.46Å; M36-L343 VanDerWaalsContact CE-CD1 3.46Å; M36-Y344 HydrophobicContact CG-CE2 4.48Å; M36-Y344 WeakPolarHBondContact CG-OH 3.49Å
37T98.7Very high96.5Very high0 Ų037.9 Ų37.90%020%0.197CC..Hα-helixtrans-65.6-50.5-178.2-58.10000111.8R33 T34 S35 S39 L40 M41 L139 F315 A316 W319R33-T37 WeakPolarHBondContact O-CB 3.36Å; R33-T37 PolarHBondContact O-N 2.96Å; R33-T37 PolarHBondContact O-OG1 3.24Å; T34-T37 PolarHBondContact O-N 3.47Å; T34-T37 VanDerWaalsContact O-N 3.15Å; S35-T37 PolarHBondContact O-N 3.45Å; T37-S39 VanDerWaalsContact C-N 3.3Å; T37-S39 PolarHBondContact O-N 3.13Å; T37-L40 PolarHBondContact O-N 2.91Å; T37-M41 HydrophobicContact CG2-CE 3.77Å; T37-M41 HydrophobicContact CG2-SD 4.22Å; T37-M41 WeakPolarHBondContact O-CG 3.35Å; T37-M41 PolarHBondContact O-N 3.35Å; T37-L139 HydrophobicContact CG2-CD1 4.35Å; T37-L139 HydrophobicContact CG2-CD2 4.04Å; T37-F315 HydrophobicContact CG2-CE1 4.43Å; T37-F315 VanDerWaalsContact OG1-CD1 3.3Å; T37-F315 WeakPolarHBondContact OG1-CD1 3.41Å; T37-A316 WeakPolarHBondContact OG1-CA 3.49Å; T37-W319 HydrophobicContact CG2-CB 3.6Å; T37-W319 HydrophobicContact CG2-CG 4.48Å
38F98.6Very high96.7Very high1 Ų139.3 Ų39.30%0.00422%0.215CC..Hα-helixtrans-63-39.7178.5-73.2-55.2000111.8L14 Y16 T34 L40 M41 Q42 F47 L139L14-F38 HydrophobicContact CD1-CE1 4.32Å; L14-F38 HydrophobicContact CD2-CE1 4.32Å; L14-F38 HydrophobicContact CG-CE1 4.47Å; Y16-F38 HydrophobicContact CD2-CB 4.03Å; Y16-F38 AromaticContact CD2-CD1 3.52Å; Y16-F38 HydrophobicContact CD2-CD1 3.52Å; Y16-F38 AromaticContact CD2-CD2 3.53Å; Y16-F38 HydrophobicContact CD2-CD2 3.53Å; Y16-F38 AromaticContact CD2-CE1 3.7Å; Y16-F38 HydrophobicContact CD2-CE1 3.7Å; Y16-F38 AromaticContact CD2-CE2 3.72Å; Y16-F38 HydrophobicContact CD2-CE2 3.72Å; Y16-F38 AromaticContact CD2-CG 3.42Å; Y16-F38 HydrophobicContact CD2-CG 3.42Å; Y16-F38 VanDerWaalsContact CD2-CG 3.42Å; Y16-F38 AromaticContact CD2-CZ 3.8Å; Y16-F38 HydrophobicContact CD2-CZ 3.8Å; Y16-F38 HydrophobicContact CE2-CB 3.74Å; Y16-F38 HydrophobicContact CE2-CD1 4.14Å; Y16-F38 AromaticContact CE2-CD2 3.77Å; Y16-F38 HydrophobicContact CE2-CD2 3.77Å; Y16-F38 HydrophobicContact CE2-CE2 4.37Å; Y16-F38 AromaticContact CE2-CG 3.64Å; Y16-F38 HydrophobicContact CE2-CG 3.64Å; Y16-F38 HydrophobicContact CG-CD1 4.27Å; Y16-F38 HydrophobicContact CG-CE1 4.24Å; T34-F38 HydrophobicContact CG2-CD2 3.65Å; T34-F38 HydrophobicContact CG2-CE2 3.41Å; T34-F38 VanDerWaalsContact CG2-CE2 3.41Å; T34-F38 WeakPolarHBondContact O-CD2 3.27Å; T34-F38 PolarHBondContact O-N 2.89Å; F38-L40 PolarHBondContact O-N 3.01Å; F38-M41 HydrophobicContact CD1-SD 4.29Å; F38-M41 PolarHBondContact O-N 3.4Å; F38-Q42 WeakPolarHBondContact O-CB 3.45Å; F38-Q42 VanDerWaalsContact O-CG 3.29Å; F38-Q42 WeakPolarHBondContact O-CG 3.31Å; F38-Q42 PolarHBondContact O-N 2.85Å; F38-F47 HydrophobicContact CB-CZ 4.36Å; F38-F47 HydrophobicContact CD1-CE1 4.15Å; F38-F47 AromaticContact CD1-CZ 3.76Å; F38-F47 HydrophobicContact CD1-CZ 3.76Å; F38-F47 HydrophobicContact CG-CZ 4.43Å; F38-L139 HydrophobicContact CD1-CD2 3.99Å; F38-L139 HydrophobicContact CE1-CD2 3.42Å; F38-L139 VanDerWaalsContact CE1-CD2 3.42Å; F38-L139 HydrophobicContact CE1-CG 4.06Å; F38-L139 HydrophobicContact CE2-CD1 4.38Å; F38-L139 HydrophobicContact CZ-CD1 4.16Å; F38-L139 HydrophobicContact CZ-CD2 3.74Å; F38-L139 HydrophobicContact CZ-CG 3.85Å
39S98.4Very high97Very high15 Ų1534.2 Ų34.211%0.10519%0.191CC..Hα-helixtrans-62-42.6176-177.80000112S35 M36 T37 Q42 A43 H338 P339S35-S39 WeakPolarHBondContact O-CB 3.28Å; S35-S39 PolarHBondContact O-N 3.24Å; M36-S39 PolarHBondContact O-N 3.3Å; T37-S39 VanDerWaalsContact C-N 3.3Å; T37-S39 PolarHBondContact O-N 3.13Å; S39-Q42 PolarHBondContact O-N 3.05Å; S39-A43 WeakPolarHBondContact O-CB 3.41Å; S39-A43 PolarHBondContact O-N 3.46Å; S39-H338 PolarHBondContact OG-ND1 3.24Å; S39-P339 WeakPolarHBondContact OG-CD 3.23Å
40L98.8Very high97.4Very high0 Ų031.4 Ų31.40%017%0.174CC..Hα-helixtrans-64.2-45.4175.6-175.765.4000111.6M36 T37 F38 Q42 A43 Y44 A316 A320 I335 Y344M36-L40 WeakPolarHBondContact O-CB 3.35Å; M36-L40 PolarHBondContact O-N 2.99Å; T37-L40 PolarHBondContact O-N 2.91Å; F38-L40 PolarHBondContact O-N 3.01Å; L40-Q42 VanDerWaalsContact C-N 3.31Å; L40-Q42 PolarHBondContact O-N 3.47Å; L40-A43 PolarHBondContact O-N 3.25Å; L40-Y44 HydrophobicContact CD1-CD2 3.94Å; L40-Y44 HydrophobicContact CD1-CE2 3.61Å; L40-Y44 HydrophobicContact CD2-CE2 4.34Å; L40-Y44 HydrophobicContact CG-CD2 3.93Å; L40-Y44 HydrophobicContact CG-CE2 3.87Å; L40-Y44 WeakPolarHBondContact O-CD2 3.27Å; L40-Y44 PolarHBondContact O-N 2.78Å; L40-A316 HydrophobicContact CD2-CB 4.09Å; L40-A320 HydrophobicContact CD2-CB 3.86Å; L40-A320 HydrophobicContact CG-CB 4.23Å; L40-I335 HydrophobicContact CD1-CD1 4Å; L40-I335 HydrophobicContact CD1-CG2 3.8Å; L40-I335 HydrophobicContact CD2-CD1 4.43Å; L40-Y344 HydrophobicContact CD1-CE1 4.49Å; L40-Y344 HydrophobicContact CD2-CE1 4.05Å
41M98.6Very high97.7Very high2 Ų234.9 Ų34.91%0.0119%0.189CC..Hα-helixtrans-59.7-40.6176.8-72.1174.9170.900112.5T37 F38 G45 L46 F47 L139 W319 A320 L323T37-M41 HydrophobicContact CG2-CE 3.77Å; T37-M41 HydrophobicContact CG2-SD 4.22Å; T37-M41 WeakPolarHBondContact O-CG 3.35Å; T37-M41 PolarHBondContact O-N 3.35Å; F38-M41 HydrophobicContact CD1-SD 4.29Å; F38-M41 PolarHBondContact O-N 3.4Å; M41-G45 PolarHBondContact O-N 3.06Å; M41-L46 HydrophobicContact CB-CB 4.46Å; M41-L46 HydrophobicContact CB-CD1 4.39Å; M41-L46 HydrophobicContact CG-CD1 4.27Å; M41-L46 WeakPolarHBondContact O-CB 3.5Å; M41-L46 PolarHBondContact O-N 2.84Å; M41-F47 HydrophobicContact CB-CD1 4.13Å; M41-F47 HydrophobicContact CB-CE1 3.82Å; M41-F47 HydrophobicContact SD-CE1 4.39Å; M41-L139 HydrophobicContact CE-CD2 3.81Å; M41-L139 HydrophobicContact SD-CD2 4.04Å; M41-W319 VanDerWaalsContact CE-C 3.42Å; M41-W319 HydrophobicContact CE-CB 3.85Å; M41-W319 HydrophobicContact CE-CE3 4.39Å; M41-W319 WeakPolarHBondContact CE-O 3.33Å; M41-A320 HydrophobicContact CG-CB 4.37Å; M41-L323 HydrophobicContact CB-CD2 4.32Å; M41-L323 HydrophobicContact CE-CB 3.88Å; M41-L323 HydrophobicContact CE-CD2 4.02Å; M41-L323 HydrophobicContact CG-CD2 4Å; M41-L323 HydrophobicContact SD-CD2 3.59Å; M41-L323 VanDerWaalsContact SD-CD2 3.59Å
42Q98.3Very high97.9Very high88 Ų8830.9 Ų30.941%0.41118%0.176SC..Hα-helixtrans-65.9-42175.3-74.2176.6-4400111.7F38 S39 L40 Y44 G45 F47F38-Q42 WeakPolarHBondContact O-CB 3.45Å; F38-Q42 VanDerWaalsContact O-CG 3.29Å; F38-Q42 WeakPolarHBondContact O-CG 3.31Å; F38-Q42 PolarHBondContact O-N 2.85Å; S39-Q42 PolarHBondContact O-N 3.05Å; L40-Q42 VanDerWaalsContact C-N 3.31Å; L40-Q42 PolarHBondContact O-N 3.47Å; Q42-Y44 VanDerWaalsContact C-N 3.31Å; Q42-Y44 PolarHBondContact O-N 3.12Å; Q42-G45 WeakPolarHBondContact O-CA 3.46Å; Q42-G45 PolarHBondContact O-N 3.31Å; Q42-F47 HydrophobicContact CG-CD1 3.89Å; Q42-F47 HydrophobicContact CG-CD2 3.67Å; Q42-F47 HydrophobicContact CG-CE1 3.9Å; Q42-F47 HydrophobicContact CG-CE2 3.67Å; Q42-F47 HydrophobicContact CG-CG 3.79Å; Q42-F47 HydrophobicContact CG-CZ 3.79Å
43A98.5Very high98Very high38 Ų3826.5 Ų26.531%0.31416%0.157SC..Hα-helixtrans-64.7-34.4178.900000112.5S39 L40 G45 P336 H338S39-A43 WeakPolarHBondContact O-CB 3.41Å; S39-A43 PolarHBondContact O-N 3.46Å; L40-A43 PolarHBondContact O-N 3.25Å; A43-G45 PolarHBondContact O-N 3.09Å; A43-P336 HydrophobicContact CB-CB 4.08Å; A43-P336 HydrophobicContact CB-CG 3.56Å; A43-H338 HydrophobicContact CB-CB 3.78Å
44Y98.6Very high98.1Very high32 Ų3232.9 Ų32.913%0.12519%0.185CC..THydrogen-bonded Turntrans-75.7-2.9168.9-81.2-63.9000114.4L40 Q42 L46 A320 L331 V332 D334 I335 P336 L350L40-Y44 HydrophobicContact CD1-CD2 3.94Å; L40-Y44 HydrophobicContact CD1-CE2 3.61Å; L40-Y44 HydrophobicContact CD2-CE2 4.34Å; L40-Y44 HydrophobicContact CG-CD2 3.93Å; L40-Y44 HydrophobicContact CG-CE2 3.87Å; L40-Y44 WeakPolarHBondContact O-CD2 3.27Å; L40-Y44 PolarHBondContact O-N 2.78Å; Q42-Y44 VanDerWaalsContact C-N 3.31Å; Q42-Y44 PolarHBondContact O-N 3.12Å; Y44-L46 VanDerWaalsContact C-N 3.28Å; Y44-L46 PolarHBondContact O-N 3.3Å; Y44-A320 HydrophobicContact CD2-CB 4.48Å; Y44-L331 HydrophobicContact CD1-CB 4.27Å; Y44-L331 HydrophobicContact CD1-CD2 3.79Å; Y44-L331 HydrophobicContact CD1-CG 4.42Å; Y44-L331 HydrophobicContact CD2-CD1 4.3Å; Y44-L331 HydrophobicContact CE1-CB 4.09Å; Y44-L331 HydrophobicContact CE1-CD2 4.44Å; Y44-L331 HydrophobicContact CE2-CD1 4.4Å; Y44-L331 HydrophobicContact CG-CD1 4.4Å; Y44-L331 HydrophobicContact CG-CD2 3.84Å; Y44-V332 HydrophobicContact CE1-CG2 3.92Å; Y44-V332 PolarHBondContact OH-O 3.19Å; Y44-D334 PolarHBondContact OH-O 3.08Å; Y44-I335 HydrophobicContact CE2-CD1 4.45Å; Y44-P336 HydrophobicContact CD1-CG 4Å; Y44-P336 HydrophobicContact CD2-CG 4.15Å; Y44-P336 VanDerWaalsContact CE1-CD 3.49Å; Y44-P336 HydrophobicContact CE1-CG 4.06Å; Y44-P336 HydrophobicContact CE2-CG 4.22Å; Y44-P336 HydrophobicContact CG-CG 4.05Å; Y44-L350 HydrophobicContact CE2-CD1 4.1Å
45G98Very high98.2Very high36 Ų3632.9 Ų32.937%0.37119%0.185SC..THydrogen-bonded Turntrans74.610.8-179.600000115M41 Q42 A43 F47 G48M41-G45 PolarHBondContact O-N 3.06Å; Q42-G45 WeakPolarHBondContact O-CA 3.46Å; Q42-G45 PolarHBondContact O-N 3.31Å; A43-G45 PolarHBondContact O-N 3.09Å; G45-F47 PolarHBondContact O-N 3.42Å; G45-G48 PolarHBondContact O-N 3.03Å
46L98Very high98.2Very high2 Ų235.6 Ų35.61%0.0120%0.2CC..G310 helixtrans-63.7-27.4-174.4-68.4175.1000113.4M41 Y44 G48 H49 A320 L323 V327 K329 L331M41-L46 HydrophobicContact CB-CB 4.46Å; M41-L46 HydrophobicContact CB-CD1 4.39Å; M41-L46 HydrophobicContact CG-CD1 4.27Å; M41-L46 WeakPolarHBondContact O-CB 3.5Å; M41-L46 PolarHBondContact O-N 2.84Å; Y44-L46 VanDerWaalsContact C-N 3.28Å; Y44-L46 PolarHBondContact O-N 3.3Å; L46-G48 PolarHBondContact O-N 3.06Å; L46-H49 PolarHBondContact O-N 2.85Å; L46-A320 WeakPolarHBondContact CD1-O 3.42Å; L46-L323 HydrophobicContact CB-CD2 3.68Å; L46-L323 HydrophobicContact CB-CG 4.19Å; L46-L323 HydrophobicContact CD1-CB 4.16Å; L46-L323 HydrophobicContact CD1-CD2 4.02Å; L46-L323 HydrophobicContact CD1-CG 4.12Å; L46-L323 HydrophobicContact CG-CD2 4.46Å; L46-V327 HydrophobicContact CD2-CG2 4.23Å; L46-K329 HydrophobicContact CD2-CB 4.38Å; L46-L331 HydrophobicContact CD1-CD2 4.32Å; L46-L331 HydrophobicContact CD2-CD2 3.97Å; L46-L331 HydrophobicContact CG-CD2 4.27Å
47F97.5Very high98.3Very high32 Ų3238.1 Ų38.114%0.1422%0.219CC..G310 helixtrans-61.5-24.8175.8-84.337.9000112.6L14 Y16 F38 M41 Q42 G45 H49 V52L14-F47 HydrophobicContact CD2-CD1 4.16Å; L14-F47 HydrophobicContact CD2-CE1 3.65Å; L14-F47 HydrophobicContact CD2-CZ 4.04Å; Y16-F47 AromaticContact CD1-CE2 3.54Å; Y16-F47 HydrophobicContact CD1-CE2 3.54Å; Y16-F47 HydrophobicContact CD1-CZ 4.09Å; Y16-F47 HydrophobicContact CD2-CE2 4.3Å; Y16-F47 HydrophobicContact CD2-CZ 4.05Å; Y16-F47 AromaticContact CE1-CE2 3.72Å; Y16-F47 HydrophobicContact CE1-CE2 3.72Å; Y16-F47 HydrophobicContact CE1-CZ 4.38Å; Y16-F47 HydrophobicContact CE2-CE2 4.45Å; Y16-F47 HydrophobicContact CE2-CZ 4.35Å; Y16-F47 AromaticContact CG-CE2 3.83Å; Y16-F47 HydrophobicContact CG-CE2 3.83Å; Y16-F47 AromaticContact CG-CZ 3.89Å; Y16-F47 HydrophobicContact CG-CZ 3.89Å; F38-F47 HydrophobicContact CB-CZ 4.36Å; F38-F47 HydrophobicContact CD1-CE1 4.15Å; F38-F47 AromaticContact CD1-CZ 3.76Å; F38-F47 HydrophobicContact CD1-CZ 3.76Å; F38-F47 HydrophobicContact CG-CZ 4.43Å; M41-F47 HydrophobicContact CB-CD1 4.13Å; M41-F47 HydrophobicContact CB-CE1 3.82Å; M41-F47 HydrophobicContact SD-CE1 4.39Å; Q42-F47 HydrophobicContact CG-CD1 3.89Å; Q42-F47 HydrophobicContact CG-CD2 3.67Å; Q42-F47 HydrophobicContact CG-CE1 3.9Å; Q42-F47 HydrophobicContact CG-CE2 3.67Å; Q42-F47 HydrophobicContact CG-CG 3.79Å; Q42-F47 HydrophobicContact CG-CZ 3.79Å; G45-F47 PolarHBondContact O-N 3.42Å; F47-H49 PolarHBondContact O-N 3.06Å; F47-V52 HydrophobicContact CB-CG2 4.38Å; F47-V52 HydrophobicContact CD2-CG2 3.81Å; F47-V52 HydrophobicContact CE2-CG2 4.29Å; F47-V52 HydrophobicContact CG-CG2 4.11Å
48G96.8Very high98.3Very high45 Ų4538.5 Ų38.546%0.46422%0.221SC..G310 helixtrans-69.1-11.9173.500000114R9 G45 L46R9-G48 WeakPolarHBondContact CD-O 3.22Å; G45-G48 PolarHBondContact O-N 3.03Å; L46-G48 PolarHBondContact O-N 3.06Å
49H97.2Very high98.2Very high68 Ų6840.5 Ų40.532%0.31524%0.236SC..G310 helixtrans-110.87.3-175.4-60.5-52.3000114.1R9 L46 F47 V327 K329R9-H49 WeakPolarHBondContact CA-O 3.46Å; L46-H49 PolarHBondContact O-N 2.85Å; F47-H49 PolarHBondContact O-N 3.06Å; H49-V327 HydrophobicContact CB-CB 4.09Å; H49-V327 HydrophobicContact CB-CG1 4.34Å; H49-V327 HydrophobicContact CB-CG2 4.01Å; H49-K329 VanDerWaalsContact CE1-CE 3.42Å; H49-K329 WeakPolarHBondContact CE1-CE 3.4Å
50V98.2Very high98.2Very high0 Ų043 Ų430%024%0.244CC..SBendtrans-134.2164.6175.4-62.90000112.4R9 V12 L14 V52 L323 V327R9-V50 PolarHBondContact NE-O 3.17Å; V12-V50 HydrophobicContact CB-CG1 3.94Å; V12-V50 HydrophobicContact CG1-CB 4.47Å; V12-V50 HydrophobicContact CG1-CG1 3.65Å; V12-V50 WeakPolarHBondContact O-CA 3.34Å; V12-V50 WeakPolarHBondContact O-CB 3.37Å; L14-V50 HydrophobicContact CB-CB 4.43Å; L14-V50 HydrophobicContact CB-CG2 3.9Å; L14-V50 HydrophobicContact CD2-CG2 4.27Å; V50-V52 HydrophobicContact CG2-CG2 3.88Å; V50-L323 HydrophobicContact CG1-CD1 3.82Å; V50-V327 HydrophobicContact CG1-CG1 3.54Å
51K98.1Very high98.1Very high77 Ų7749.5 Ų49.534%0.33528%0.275SS..EExtended strand (participates in β ladder)trans-83.7101.8162.6-179.1-178.2174.9-174.30108.7R9 V12 A13 L14 E132R9-K51 PolarHBondContact O-N 3.2Å; V12-K51 PolarHBondContact O-N 2.77Å; A13-K51 CarbonylContact C-O 3.53Å; A13-K51 WeakPolarHBondContact CA-O 3.29Å; A13-K51 HydrophobicContact CB-CB 4.48Å; L14-K51 PolarHBondContact N-O 2.72Å; K51-E132 IonicContact NZ-OE2 3.78Å; K51-E132 PolarHBondContact NZ-OE2 2.82Å
52V98.3Very high98.1Very high54 Ų5453 Ų5333%0.32729%0.291SS..EExtended strand (participates in β ladder)trans-78.3131.1172.7-178.50000109.4L14 Y16 F47 V50L14-V52 WeakPolarHBondContact O-CA 3.4Å; Y16-V52 HydrophobicContact CD1-CG1 3.83Å; Y16-V52 HydrophobicContact CG-CG1 4.32Å; F47-V52 HydrophobicContact CB-CG2 4.38Å; F47-V52 HydrophobicContact CD2-CG2 3.81Å; F47-V52 HydrophobicContact CE2-CG2 4.29Å; F47-V52 HydrophobicContact CG-CG2 4.11Å; V50-V52 HydrophobicContact CG2-CG2 3.88Å
53F98.5Very high98.1Very high31 Ų3148.8 Ų48.814%0.13627%0.272CS..EExtended strand (participates in β ladder)trans-129.4145.5174.377.5-84.7000111.5A13 L14 A15 Y16 P55 Q123 C124 L127A13-F53 HydrophobicContact CB-CD1 4.16Å; A13-F53 HydrophobicContact CB-CE1 4.27Å; L14-F53 WeakPolarHBondContact O-CD1 3.24Å; L14-F53 PolarHBondContact O-N 3.28Å; A15-F53 HydrophobicContact CB-CE1 3.75Å; A15-F53 HydrophobicContact CB-CE2 4.2Å; A15-F53 HydrophobicContact CB-CZ 3.54Å; Y16-F53 PolarHBondContact N-O 3.37Å; Y16-F53 CarbonylContact O-C 3.57Å; F53-P55 HydrophobicContact CE2-CB 4.19Å; F53-P55 WeakPolarHBondContact O-CD 3.43Å; F53-Q123 HydrophobicContact CE2-CB 3.93Å; F53-Q123 HydrophobicContact CZ-CB 4.29Å; F53-C124 VanDerWaalsContact CZ-SG 3.56Å; F53-L127 HydrophobicContact CD1-CD1 4Å; F53-L127 HydrophobicContact CE1-CD1 3.77Å; F53-L127 HydrophobicContact CZ-CD1 4.14Å
54K98.6Very high98Very high137 Ų13748.8 Ų48.860%0.59627%0.272SS*.  trans-79.3118.5173.7174.9174-176.7-177.90108.8
55P98.6Very high97.9Very high3 Ų355.2 Ų55.22%0.01930%0.297CS..  trans-75.8163.3175.931.1-33.5000112.1L20 F53 L116 A120L20-P55 HydrophobicContact CB-CG 4.44Å; L20-P55 HydrophobicContact CD2-CG 4.1Å; F53-P55 HydrophobicContact CE2-CB 4.19Å; F53-P55 WeakPolarHBondContact O-CD 3.43Å; P55-L116 HydrophobicContact CB-CD1 4.34Å; P55-L116 HydrophobicContact CG-CD1 4.16Å; P55-A120 HydrophobicContact CB-CB 3.46Å; P55-A120 VanDerWaalsContact CB-CB 3.46Å; P55-A120 HydrophobicContact CG-CB 3.96Å
56T98.5Very high97.9Very high81 Ų8154.8 Ų54.850%0.49729%0.285SS..  trans-119.6154.8172.957.50000110.1G119 Q123T56-G119 CarbonylContact O-C 3.58Å; T56-G119 VanDerWaalsContact O-CA 3.31Å; T56-G119 WeakPolarHBondContact O-CA 3.5Å; T56-Q123 PolarHBondContact OG1-NE2 3.44Å
57S98.6Very high97.9Very high59 Ų5954.7 Ų54.741%0.41328%0.284SS..PPolyproline II helixtrans-63.5140.6175.6-61.90000112.1T115S57-T115 WeakPolarHBondContact CA-O 3.19Å
58A98.7Very high97.9Very high7 Ų753.5 Ų53.56%0.05828%0.28CS..PPolyproline II helixtrans-62.4138.5169.600000110.4E62 L63 T115 T118 I122A58-E62 VanDerWaalsContact CA-OE2 3.28Å; A58-E62 WeakPolarHBondContact CA-OE2 3.34Å; A58-E62 HydrophobicContact CB-CB 4.41Å; A58-L63 HydrophobicContact CB-CD2 3.89Å; A58-L63 HydrophobicContact CB-CG 4.09Å; A58-T115 PolarHBondContact N-O 3.41Å; A58-T118 HydrophobicContact CB-CG2 4.15Å; A58-I122 HydrophobicContact CB-CD1 4.16Å
59S98.1Very high97.9Very high43 Ų4355.4 Ų55.430%0.30129%0.286SS..PPolyproline II helixtrans-74.8162173.8920000111.4E61 E62 L63S59-E61 WeakPolarHBondContact CB-OE2 2.93Å; S59-E61 PolarHBondContact O-N 3.35Å; S59-E61 PolarHBondContact OG-N 3.15Å; S59-E61 PolarHBondContact OG-OE2 3.02Å; S59-E62 PolarHBondContact N-OE2 2.85Å; S59-E62 PolarHBondContact O-N 2.98Å; S59-E62 VanDerWaalsContact O-N 3.17Å; S59-E62 PolarHBondContact OG-N 3.1Å; S59-L63 WeakPolarHBondContact O-CG 3.46Å; S59-L63 PolarHBondContact O-N 3.32Å
60K97.1Very high97.8Very high67 Ų6756.7 Ų56.729%0.29130%0.296SS..Hα-helixtrans-58.4-35.6174.5-75.3-173.6174.6-172.20111.4L63 A64 V72 E73 H76 Y111K60-L63 PolarHBondContact O-N 2.86Å; K60-A64 WeakPolarHBondContact O-CB 3.45Å; K60-A64 PolarHBondContact O-N 2.65Å; K60-V72 HydrophobicContact CG-CG1 4.16Å; K60-E73 IonicContact NZ-OE1 3.85Å; K60-E73 PolarHBondContact NZ-OE1 3.04Å; K60-E73 IonicContact NZ-OE2 2.93Å; K60-E73 PolarHBondContact NZ-OE2 2.85Å; K60-H76 PolarHBondContact NZ-ND1 2.99Å; K60-Y111 WeakPolarHBondContact CG-OH 3.37Å
61E97.3Very high97.8Very high138 Ų13856.7 Ų56.765%0.64530%0.296SS*.Hα-helixtrans-67.2-40.8177.5-5772.8-157.300112S59 A64 Y65S59-E61 WeakPolarHBondContact CB-OE2 2.93Å; S59-E61 PolarHBondContact O-N 3.35Å; S59-E61 PolarHBondContact OG-N 3.15Å; S59-E61 PolarHBondContact OG-OE2 3.02Å; E61-A64 PolarHBondContact O-N 2.93Å; E61-Y65 PolarHBondContact O-N 3.21Å
62E98.2Very high97.7Very high75 Ų7553.2 Ų53.235%0.3528%0.28SS..Hα-helixtrans-65-42.8174.9-71.3177.3131.500111.3A58 S59 Y65 I122 L162A58-E62 VanDerWaalsContact CA-OE2 3.28Å; A58-E62 WeakPolarHBondContact CA-OE2 3.34Å; A58-E62 HydrophobicContact CB-CB 4.41Å; S59-E62 PolarHBondContact N-OE2 2.85Å; S59-E62 PolarHBondContact O-N 2.98Å; S59-E62 VanDerWaalsContact O-N 3.17Å; S59-E62 PolarHBondContact OG-N 3.1Å; E62-Y65 VanDerWaalsContact O-CB 3.32Å; E62-Y65 WeakPolarHBondContact O-CB 3.35Å; E62-Y65 PolarHBondContact O-N 2.79Å; E62-I122 HydrophobicContact CB-CD1 4.03Å; E62-L162 VanDerWaalsContact O-CD2 3.26Å; E62-L162 WeakPolarHBondContact O-CD2 3.28Å
63L98.5Very high97.6Very high0 Ų054.9 Ų54.90%029%0.285CS..Hα-helixtrans-64-41.5176.4-62.8169.9000111.7A58 S59 K60 Y65 F66 H67 V72 Y111 T115 T118 F157 L162A58-L63 HydrophobicContact CB-CD2 3.89Å; A58-L63 HydrophobicContact CB-CG 4.09Å; S59-L63 WeakPolarHBondContact O-CG 3.46Å; S59-L63 PolarHBondContact O-N 3.32Å; K60-L63 PolarHBondContact O-N 2.86Å; L63-Y65 PolarHBondContact O-N 3.03Å; L63-Y65 VanDerWaalsContact O-N 3.15Å; L63-F66 PolarHBondContact O-N 2.96Å; L63-H67 PolarHBondContact O-N 3.09Å; L63-V72 HydrophobicContact CB-CG1 4.27Å; L63-V72 HydrophobicContact CB-CG2 3.94Å; L63-V72 HydrophobicContact CD1-CG1 3.96Å; L63-Y111 HydrophobicContact CD1-CE2 4.42Å; L63-T115 HydrophobicContact CD1-CG2 3.72Å; L63-T118 HydrophobicContact CD2-CG2 3.77Å; L63-F157 HydrophobicContact CD1-CE1 3.94Å; L63-F157 HydrophobicContact CD1-CZ 4.04Å; L63-F157 HydrophobicContact CD2-CD1 3.79Å; L63-F157 HydrophobicContact CD2-CE1 4.05Å; L63-F157 HydrophobicContact CD2-CG 4.1Å; L63-F157 HydrophobicContact CG-CE1 4.42Å; L63-L162 HydrophobicContact CD2-CD1 4.12Å
64A97.1Very high97.5Very high38 Ų3854 Ų5431%0.31428%0.281SS..THydrogen-bonded Turntrans-69.6-5.7-179.100000114.1K60 E61 F66 H67K60-A64 WeakPolarHBondContact O-CB 3.45Å; K60-A64 PolarHBondContact O-N 2.65Å; E61-A64 PolarHBondContact O-N 2.93Å; A64-F66 PolarHBondContact O-N 3.01Å; A64-H67 WeakPolarHBondContact CA-O 3.32Å
65Y96.6Very high97.3Very high167 Ų16747.5 Ų47.566%0.65525%0.253SS*.THydrogen-bonded Turntrans-65.6-26.1172-134.1-101.9000112.4E61 E62 L63 L165E61-Y65 PolarHBondContact O-N 3.21Å; E62-Y65 VanDerWaalsContact O-CB 3.32Å; E62-Y65 WeakPolarHBondContact O-CB 3.35Å; E62-Y65 PolarHBondContact O-N 2.79Å; L63-Y65 PolarHBondContact O-N 3.03Å; L63-Y65 VanDerWaalsContact O-N 3.15Å; Y65-L165 HydrophobicContact CD1-CB 4.35Å; Y65-L165 HydrophobicContact CD1-CD1 4.2Å
66F97.4Very high97.2Very high27 Ų2750.3 Ų50.312%0.11827%0.265CS..THydrogen-bonded Turntrans-119.6-54.1171.9172.9-120.7000111.5L63 A64 R148 N158 V161 L162 L165 A192L63-F66 PolarHBondContact O-N 2.96Å; A64-F66 PolarHBondContact O-N 3.01Å; F66-R148 HydrophobicContact CE2-CB 4.2Å; F66-R148 HydrophobicContact CZ-CB 4.16Å; F66-R148 VanDerWaalsContact O-CG 3.31Å; F66-R148 WeakPolarHBondContact O-CG 3.43Å; F66-R148 PolarHBondContact O-NE 2.93Å; F66-N158 HydrophobicContact CD1-CB 4.09Å; F66-N158 HydrophobicContact CE1-CB 3.73Å; F66-V161 HydrophobicContact CB-CG1 4.01Å; F66-V161 HydrophobicContact CD1-CB 4.25Å; F66-V161 HydrophobicContact CD1-CG1 4.01Å; F66-V161 HydrophobicContact CD2-CG1 3.58Å; F66-V161 HydrophobicContact CE1-CB 4.41Å; F66-V161 HydrophobicContact CE1-CG1 4.37Å; F66-V161 HydrophobicContact CE1-CG2 4.46Å; F66-V161 HydrophobicContact CE2-CG1 3.97Å; F66-V161 HydrophobicContact CG-CB 4.33Å; F66-V161 HydrophobicContact CG-CG1 3.59Å; F66-V161 HydrophobicContact CZ-CG1 4.35Å; F66-V161 HydrophobicContact CZ-CG2 4.37Å; F66-L162 HydrophobicContact CB-CD2 3.72Å; F66-L162 HydrophobicContact CB-CG 4.26Å; F66-L165 HydrophobicContact CB-CD1 4.1Å; F66-A192 HydrophobicContact CE2-CB 3.84Å; F66-A192 HydrophobicContact CZ-CB 4.33Å
67H97.6Very high96.9Very high0 Ų047.2 Ų47.20%025%0.247CC..SBendtrans-72.7152.1-173.2-66.1-73.9000112.3L63 A64 Y71 V72 R147 R148 F157 N158L63-H67 PolarHBondContact O-N 3.09Å; A64-H67 WeakPolarHBondContact CA-O 3.32Å; H67-Y71 HydrophobicContact CB-CD1 4.23Å; H67-Y71 AromaticContact ND1-CD1 3.92Å; H67-Y71 AromaticContact ND1-CE1 3.83Å; H67-V72 HydrophobicContact CB-CG2 3.7Å; H67-R147 PolarHBondContact CE1-O 3.41Å; H67-R147 PolarHBondContact ND1-O 3.06Å; H67-R148 CarbonylContact C-O 3.5Å; H67-R148 WeakPolarHBondContact CA-O 3.41Å; H67-R148 PolarHBondContact ND1-O 3.31Å; H67-F157 AromaticContact CD2-CD1 3.79Å; H67-F157 WeakPolarHBondContact NE2-CA 3.35Å; H67-F157 AromaticContact NE2-CD1 3.86Å; H67-N158 PolarHBondContact CE1-N 2.89Å; H67-N158 PolarHBondContact NE2-N 2.93Å
68S97.1Very high96.5Very high6 Ų644.5 Ų44.54%0.04223%0.228CC..  trans-72.1142.6173.3660000111D70 Y71 V72 R148 S149S68-D70 VanDerWaalsContact C-N 3.27Å; S68-D70 WeakPolarHBondContact CB-OD1 3.36Å; S68-D70 PolarHBondContact O-N 3.04Å; S68-D70 PolarHBondContact OG-OD1 3.16Å; S68-Y71 PolarHBondContact O-N 3.07Å; S68-Y71 VanDerWaalsContact O-N 3.15Å; S68-Y71 VanDerWaalsContact OG-CB 3.32Å; S68-Y71 WeakPolarHBondContact OG-CB 3.31Å; S68-V72 WeakPolarHBondContact O-CG2 3.34Å; S68-V72 PolarHBondContact O-N 3.11Å; S68-R148 PolarHBondContact N-O 3.33Å; S68-S149 VanDerWaalsContact CB-OG 3.22Å; S68-S149 WeakPolarHBondContact CB-OG 3.27Å; S68-S149 WeakPolarHBondContact OG-CB 3.22Å; S68-S149 PolarHBondContact OG-OG 3.42Å
69S96.9Very high95.9Very high86 Ų8646.4 Ų46.460%0.60124%0.241SC*.Hα-helixtrans-63-33.6-174.5-53.40000113.1V72 E73S69-V72 PolarHBondContact O-N 2.98Å; S69-E73 WeakPolarHBondContact O-CB 3.5Å; S69-E73 PolarHBondContact O-N 3.37Å
70D96.2Very high95.5Very high95 Ų9548.7 Ų48.751%0.50825%0.247SC..Hα-helixtrans-64.8-4217456.5-17000112.3S68 E73 F74 F98S68-D70 VanDerWaalsContact C-N 3.27Å; S68-D70 WeakPolarHBondContact CB-OD1 3.36Å; S68-D70 PolarHBondContact O-N 3.04Å; S68-D70 PolarHBondContact OG-OD1 3.16Å; D70-E73 PolarHBondContact O-N 2.8Å; D70-F74 WeakPolarHBondContact O-CB 3.33Å; D70-F74 PolarHBondContact O-N 3.01Å; D70-F98 HydrophobicContact CB-CZ 4.37Å
71Y96.9Very high94.8Very high0 Ų051 Ų510%027%0.269CS..Hα-helixtrans-65.3-42.6174.8177.4-112.1000112H67 S68 E73 F74 L75 F98 A151 Y156H67-Y71 HydrophobicContact CB-CD1 4.23Å; H67-Y71 AromaticContact ND1-CD1 3.92Å; H67-Y71 AromaticContact ND1-CE1 3.83Å; S68-Y71 PolarHBondContact O-N 3.07Å; S68-Y71 VanDerWaalsContact O-N 3.15Å; S68-Y71 VanDerWaalsContact OG-CB 3.32Å; S68-Y71 WeakPolarHBondContact OG-CB 3.31Å; Y71-E73 VanDerWaalsContact C-N 3.34Å; Y71-E73 PolarHBondContact O-N 3.21Å; Y71-F74 WeakPolarHBondContact O-CB 3.28Å; Y71-F74 PolarHBondContact O-N 3.11Å; Y71-L75 HydrophobicContact CD1-CD1 4.34Å; Y71-L75 HydrophobicContact CE1-CD1 3.65Å; Y71-L75 HydrophobicContact CE1-CG 4.41Å; Y71-L75 HydrophobicContact CE2-CD1 4.14Å; Y71-L75 HydrophobicContact CE2-CD2 4.37Å; Y71-L75 HydrophobicContact CE2-CG 4.13Å; Y71-L75 PolarHBondContact O-N 3.17Å; Y71-F98 HydrophobicContact CD2-CB 3.95Å; Y71-F98 AromaticContact CD2-CD1 3.74Å; Y71-F98 HydrophobicContact CD2-CD1 3.74Å; Y71-F98 HydrophobicContact CD2-CD2 4.38Å; Y71-F98 HydrophobicContact CD2-CE1 4.28Å; Y71-F98 AromaticContact CD2-CG 3.78Å; Y71-F98 HydrophobicContact CD2-CG 3.78Å; Y71-F98 HydrophobicContact CE2-CB 4.06Å; Y71-F98 HydrophobicContact CE2-CG 4.4Å; Y71-A151 VanDerWaalsContact OH-CA 3.29Å; Y71-A151 WeakPolarHBondContact OH-CA 3.24Å; Y71-A151 VanDerWaalsContact OH-CB 3.28Å; Y71-A151 WeakPolarHBondContact OH-CB 3.4Å; Y71-A151 PolarHBondContact OH-N 2.9Å; Y71-Y156 VanDerWaalsContact CE1-O 3.32Å; Y71-Y156 WeakPolarHBondContact CE1-O 3.42Å; Y71-Y156 PolarHBondContact OH-O 3.41Å
72V97.6Very high94.2Very high3 Ų352.6 Ų52.62%0.01828%0.282CS..Hα-helixtrans-62.3-42.5175.21760000111.1K60 L63 H67 S68 S69 L75 H76 Y111 F157K60-V72 HydrophobicContact CG-CG1 4.16Å; L63-V72 HydrophobicContact CB-CG1 4.27Å; L63-V72 HydrophobicContact CB-CG2 3.94Å; L63-V72 HydrophobicContact CD1-CG1 3.96Å; H67-V72 HydrophobicContact CB-CG2 3.7Å; S68-V72 WeakPolarHBondContact O-CG2 3.34Å; S68-V72 PolarHBondContact O-N 3.11Å; S69-V72 PolarHBondContact O-N 2.98Å; V72-L75 PolarHBondContact O-N 2.89Å; V72-H76 WeakPolarHBondContact O-CB 3.21Å; V72-H76 PolarHBondContact O-N 3.43Å; V72-Y111 HydrophobicContact CG1-CE2 4.4Å; V72-F157 HydrophobicContact CG2-CE1 4.38Å
73E95.6Very high93.7Very high90 Ų9053.4 Ų53.442%0.42128%0.282SS..Hα-helixtrans-67.8-38.7177.9-163.161.3-127.100112K60 S69 D70 Y71 H76 S77K60-E73 IonicContact NZ-OE1 3.85Å; K60-E73 PolarHBondContact NZ-OE1 3.04Å; K60-E73 IonicContact NZ-OE2 2.93Å; K60-E73 PolarHBondContact NZ-OE2 2.85Å; S69-E73 WeakPolarHBondContact O-CB 3.5Å; S69-E73 PolarHBondContact O-N 3.37Å; D70-E73 PolarHBondContact O-N 2.8Å; Y71-E73 VanDerWaalsContact C-N 3.34Å; Y71-E73 PolarHBondContact O-N 3.21Å; E73-H76 WeakPolarHBondContact O-CB 3.43Å; E73-H76 PolarHBondContact O-N 3.41Å; E73-H76 IonicContact OE1-CE1 3.84Å; E73-H76 IonicContact OE1-CG 2.87Å; E73-H76 IonicContact OE1-ND1 3.97Å; E73-H76 PolarHBondContact OE1-ND1 3.03Å; E73-S77 PolarHBondContact O-N 3Å
74F95.8Very high93.4Very high12 Ų1257.4 Ų57.45%0.05330%0.303CS..Hα-helixtrans-58.5-51.4173.7171.9-93.7000111.5D70 Y71 H76 S77 S78 L88 F98 V100 L106D70-F74 WeakPolarHBondContact O-CB 3.33Å; D70-F74 PolarHBondContact O-N 3.01Å; Y71-F74 WeakPolarHBondContact O-CB 3.28Å; Y71-F74 PolarHBondContact O-N 3.11Å; F74-H76 VanDerWaalsContact C-N 3.27Å; F74-H76 PolarHBondContact O-N 2.83Å; F74-S77 WeakPolarHBondContact O-CB 3.28Å; F74-S77 PolarHBondContact O-N 3Å; F74-S77 VanDerWaalsContact O-N 3.1Å; F74-S77 PolarHBondContact O-OG 3.37Å; F74-S78 PolarHBondContact O-N 3.09Å; F74-L88 HydrophobicContact CD2-CD1 3.95Å; F74-L88 HydrophobicContact CE2-CD1 3.38Å; F74-L88 HydrophobicContact CE2-CG 3.77Å; F74-L88 WeakPolarHBondContact CE2-O 3.38Å; F74-L88 HydrophobicContact CZ-CD1 4.04Å; F74-L88 HydrophobicContact CZ-CG 3.9Å; F74-L88 WeakPolarHBondContact CZ-O 3.33Å; F74-F98 HydrophobicContact CB-CD2 3.79Å; F74-F98 HydrophobicContact CB-CE2 3.49Å; F74-F98 VanDerWaalsContact CB-CE2 3.49Å; F74-F98 HydrophobicContact CB-CZ 4.42Å; F74-F98 HydrophobicContact CD1-CB 4.43Å; F74-F98 AromaticContact CD1-CD2 3.57Å; F74-F98 HydrophobicContact CD1-CD2 3.57Å; F74-F98 HydrophobicContact CD1-CE2 4.21Å; F74-F98 HydrophobicContact CD1-CG 4.36Å; F74-F98 AromaticContact CD2-CD2 3.72Å; F74-F98 HydrophobicContact CD2-CD2 3.72Å; F74-F98 AromaticContact CD2-CE2 3.88Å; F74-F98 HydrophobicContact CD2-CE2 3.88Å; F74-F98 HydrophobicContact CE1-CB 4.45Å; F74-F98 HydrophobicContact CE1-CD2 4.1Å; F74-F98 HydrophobicContact CE2-CD2 4.21Å; F74-F98 AromaticContact CG-CD2 3.38Å; F74-F98 HydrophobicContact CG-CD2 3.38Å; F74-F98 AromaticContact CG-CE2 3.58Å; F74-F98 HydrophobicContact CG-CE2 3.58Å; F74-F98 HydrophobicContact CZ-CD2 4.4Å; F74-V100 HydrophobicContact CE1-CB 4.42Å; F74-V100 HydrophobicContact CE1-CG1 3.9Å; F74-V100 HydrophobicContact CE1-CG2 3.77Å; F74-V100 HydrophobicContact CZ-CG2 3.72Å; F74-L106 HydrophobicContact CE1-CD1 4.44Å; F74-L106 HydrophobicContact CZ-CD1 4.17Å
75L95.8Very high93.2Very high0 Ų057.6 Ų57.60%030%0.299CS..Hα-helixtrans-63.2-35.4177.1-68.7-177.3000111.9Y71 V72 S77 S78 V100 L106 L110 Y111 Y156 F157Y71-L75 HydrophobicContact CD1-CD1 4.34Å; Y71-L75 HydrophobicContact CE1-CD1 3.65Å; Y71-L75 HydrophobicContact CE1-CG 4.41Å; Y71-L75 HydrophobicContact CE2-CD1 4.14Å; Y71-L75 HydrophobicContact CE2-CD2 4.37Å; Y71-L75 HydrophobicContact CE2-CG 4.13Å; Y71-L75 PolarHBondContact O-N 3.17Å; V72-L75 PolarHBondContact O-N 2.89Å; L75-S77 VanDerWaalsContact C-N 3.29Å; L75-S77 PolarHBondContact O-N 3.16Å; L75-S78 WeakPolarHBondContact O-CB 3.47Å; L75-S78 PolarHBondContact O-N 2.97Å; L75-S78 PolarHBondContact O-OG 3.35Å; L75-V100 HydrophobicContact CD2-CG1 4.32Å; L75-L106 HydrophobicContact CD2-CD2 4.29Å; L75-L110 HydrophobicContact CD2-CD2 4.03Å; L75-Y111 HydrophobicContact CB-CD2 4.14Å; L75-Y156 HydrophobicContact CD2-CD1 4.2Å; L75-F157 HydrophobicContact CB-CZ 4.14Å; L75-F157 HydrophobicContact CD1-CD1 4.32Å; L75-F157 HydrophobicContact CD1-CE1 3.66Å; L75-F157 HydrophobicContact CD1-CE2 3.98Å; L75-F157 HydrophobicContact CD1-CZ 3.47Å; L75-F157 VanDerWaalsContact CD1-CZ 3.47Å; L75-F157 HydrophobicContact CG-CZ 4.49Å
76H95.3Very high93Very high62 Ų6254.8 Ų54.829%0.28729%0.291SS..Hα-helixtrans-61.1-38.8174.4177.2-109.3000112K60 V72 E73 F74 S78 S79 Y111K60-H76 PolarHBondContact NZ-ND1 2.99Å; V72-H76 WeakPolarHBondContact O-CB 3.21Å; V72-H76 PolarHBondContact O-N 3.43Å; E73-H76 WeakPolarHBondContact O-CB 3.43Å; E73-H76 PolarHBondContact O-N 3.41Å; E73-H76 IonicContact OE1-CE1 3.84Å; E73-H76 IonicContact OE1-CG 2.87Å; E73-H76 IonicContact OE1-ND1 3.97Å; E73-H76 PolarHBondContact OE1-ND1 3.03Å; F74-H76 VanDerWaalsContact C-N 3.27Å; F74-H76 PolarHBondContact O-N 2.83Å; H76-S78 PolarHBondContact O-N 3.44Å; H76-S79 PolarHBondContact O-N 3.19Å; H76-Y111 HydrophobicContact CB-CD2 3.9Å; H76-Y111 HydrophobicContact CB-CE1 4.41Å; H76-Y111 HydrophobicContact CB-CE2 3.61Å; H76-Y111 HydrophobicContact CB-CG 4.38Å; H76-Y111 AromaticContact CD2-CD1 3.81Å; H76-Y111 AromaticContact CD2-CE1 3.54Å; H76-Y111 AromaticContact CD2-CZ 3.81Å
77S92.4Very high92.8Very high16 Ų1658.5 Ų58.511%0.11231%0.312CS..Hα-helixtrans-63.6-22.1177.781.50000113.5E73 F74 L75 S79 E80 L88E73-S77 PolarHBondContact O-N 3Å; F74-S77 WeakPolarHBondContact O-CB 3.28Å; F74-S77 PolarHBondContact O-N 3Å; F74-S77 VanDerWaalsContact O-N 3.1Å; F74-S77 PolarHBondContact O-OG 3.37Å; L75-S77 VanDerWaalsContact C-N 3.29Å; L75-S77 PolarHBondContact O-N 3.16Å; S77-S79 PolarHBondContact O-N 3.29Å; S77-E80 WeakPolarHBondContact O-CB 3.38Å; S77-E80 PolarHBondContact O-N 3.26Å; S77-E80 VanDerWaalsContact O-N 3.11Å; S77-L88 WeakPolarHBondContact OG-CD2 3.28Å
78S90Very high92.6Very high2 Ų258.6 Ų58.61%0.01431%0.312CS..THydrogen-bonded Turntrans-67.9-14.5175.692.70000112.9F74 L75 H76 L85F74-S78 PolarHBondContact O-N 3.09Å; L75-S78 WeakPolarHBondContact O-CB 3.47Å; L75-S78 PolarHBondContact O-N 2.97Å; L75-S78 PolarHBondContact O-OG 3.35Å; H76-S78 PolarHBondContact O-N 3.44Å; S78-L85 WeakPolarHBondContact O-CD2 3.13Å
79S86.5Confident92.4Very high47 Ų4760.1 Ų60.133%0.32932%0.319SS..THydrogen-bonded Turntrans-96.31.8175.5-720000113.6H76 S77 S108 Y111H76-S79 PolarHBondContact O-N 3.19Å; S77-S79 PolarHBondContact O-N 3.29Å; S79-S108 PolarHBondContact OG-O 3.01Å; S79-Y111 WeakPolarHBondContact OG-CB 3.44Å
80E88.8Confident92.2Very high92 Ų9262.5 Ų62.543%0.4331%0.314SS..SBendtrans-68.3134.3176.9-72-178.6170.300111.8S77 N82 R83S77-E80 WeakPolarHBondContact O-CB 3.38Å; S77-E80 PolarHBondContact O-N 3.26Å; S77-E80 VanDerWaalsContact O-N 3.11Å; E80-N82 PolarHBondContact O-N 3.32Å; E80-R83 HydrophobicContact CB-CB 4.19Å; E80-R83 WeakPolarHBondContact O-CB 3.37Å; E80-R83 PolarHBondContact O-N 3.19Å
81P83.3Confident92Very high115 Ų11560.8 Ų60.875%0.74730%0.304SS*.THydrogen-bonded Turntrans-57.2135.6175.1-22.932.4000111.6R83P81-R83 PolarHBondContact O-N 2.85Å
82N84.2Confident91.7Very high171 Ų17160.8 Ų60.891%0.91430%0.304SS*.THydrogen-bonded Turntrans65.310.1-180-45.5-59.5000115.7E80 N84E80-N82 PolarHBondContact O-N 3.32Å; N82-N84 PolarHBondContact O-N 3.01Å
83R88.1Confident91.3Very high93 Ų9366.2 Ų66.235%0.35133%0.329SS..  trans-63.4129.8171-167.174.2-174.2-175.61.9109.3E80 P81 L85 L88 E91E80-R83 HydrophobicContact CB-CB 4.19Å; E80-R83 WeakPolarHBondContact O-CB 3.37Å; E80-R83 PolarHBondContact O-N 3.19Å; P81-R83 PolarHBondContact O-N 2.85Å; R83-L85 PolarHBondContact O-N 3.45Å; R83-L88 HydrophobicContact CG-CB 4.44Å; R83-L88 HydrophobicContact CG-CD2 4Å; R83-E91 IonicContact NH2-OE1 3.67Å; R83-E91 IonicContact NH2-OE2 3.83Å; R83-E91 PolarHBondContact NH2-OE2 3.44Å
84N92.8Very high90.8Very high84 Ų8468.6 Ų68.645%0.44934%0.344SS..  trans-77.6105.1171.4-176-32.9000108.4N82 E86 L87 L88N82-N84 PolarHBondContact O-N 3.01Å; N84-E86 PolarHBondContact O-N 2.89Å; N84-E86 PolarHBondContact OD1-N 2.74Å; N84-E86 VanDerWaalsContact OD1-N 3.13Å; N84-L87 HydrophobicContact CB-CB 4.11Å; N84-L87 HydrophobicContact CB-CD1 3.93Å; N84-L87 HydrophobicContact CB-CG 4.14Å; N84-L87 PolarHBondContact O-N 2.77Å; N84-L87 PolarHBondContact OD1-N 2.97Å; N84-L87 VanDerWaalsContact OD1-N 3.12Å; N84-L88 PolarHBondContact O-N 2.91Å
85L93.1Very high90.4Very high42 Ų4274.8 Ų74.822%0.2237%0.373CS..Hα-helixtrans-65.9-35.6-175.7-63.7-179.7000112.7S78 R83 L87 L88 E89 L106S78-L85 WeakPolarHBondContact O-CD2 3.13Å; R83-L85 PolarHBondContact O-N 3.45Å; L85-L87 VanDerWaalsContact C-N 3.34Å; L85-L87 PolarHBondContact O-N 2.87Å; L85-L88 PolarHBondContact O-N 3.19Å; L85-E89 WeakPolarHBondContact O-CB 3.26Å; L85-E89 VanDerWaalsContact O-CG 3.32Å; L85-E89 WeakPolarHBondContact O-CG 3.47Å; L85-E89 PolarHBondContact O-N 2.93Å; L85-L106 HydrophobicContact CB-CB 4.34Å; L85-L106 HydrophobicContact CD2-CB 4.25Å
86E92.4Very high90Very high108 Ų10879 Ų7951%0.50539%0.392SS..Hα-helixtrans-66.7-37.8177.8-166.1-170.2158.600111.3N84 R90N84-E86 PolarHBondContact O-N 2.89Å; N84-E86 PolarHBondContact OD1-N 2.74Å; N84-E86 VanDerWaalsContact OD1-N 3.13Å; E86-R90 WeakPolarHBondContact O-CG 3.45Å; E86-R90 PolarHBondContact O-N 2.91Å; E86-R90 IonicContact OE1-CZ 2.76Å; E86-R90 IonicContact OE1-NE 3.41Å; E86-R90 IonicContact OE1-NH2 3.79Å; E86-R90 PolarHBondContact OE1-NH2 3.17Å
87L93.2Very high89.8Confident105 Ų10577.8 Ų77.855%0.5540%0.396SS..Hα-helixtrans-68.5-40.6173.3-69.2178.4000111.7N84 L85 R90 E91N84-L87 HydrophobicContact CB-CB 4.11Å; N84-L87 HydrophobicContact CB-CD1 3.93Å; N84-L87 HydrophobicContact CB-CG 4.14Å; N84-L87 PolarHBondContact O-N 2.77Å; N84-L87 PolarHBondContact OD1-N 2.97Å; N84-L87 VanDerWaalsContact OD1-N 3.12Å; L85-L87 VanDerWaalsContact C-N 3.34Å; L85-L87 PolarHBondContact O-N 2.87Å; L87-R90 PolarHBondContact O-N 3.17Å; L87-E91 WeakPolarHBondContact O-CB 3.43Å; L87-E91 PolarHBondContact O-N 2.89Å
88L93.1Very high90Very high1 Ų177.4 Ų77.41%0.00539%0.392CS..Hα-helixtrans-66.5-36.9177.8-177.265.3000112F74 S77 R83 N84 L85 E91 G92 L106F74-L88 HydrophobicContact CD2-CD1 3.95Å; F74-L88 HydrophobicContact CE2-CD1 3.38Å; F74-L88 HydrophobicContact CE2-CG 3.77Å; F74-L88 WeakPolarHBondContact CE2-O 3.38Å; F74-L88 HydrophobicContact CZ-CD1 4.04Å; F74-L88 HydrophobicContact CZ-CG 3.9Å; F74-L88 WeakPolarHBondContact CZ-O 3.33Å; S77-L88 WeakPolarHBondContact OG-CD2 3.28Å; R83-L88 HydrophobicContact CG-CB 4.44Å; R83-L88 HydrophobicContact CG-CD2 4Å; N84-L88 PolarHBondContact O-N 2.91Å; L85-L88 PolarHBondContact O-N 3.19Å; L88-E91 PolarHBondContact O-N 3.34Å; L88-G92 PolarHBondContact O-N 2.94Å; L88-L106 HydrophobicContact CB-CD1 4.07Å; L88-L106 HydrophobicContact CD2-CD1 3.67Å; L88-L106 HydrophobicContact CG-CD1 3.7Å
89E92.9Very high90.2Very high39 Ų3978.2 Ų78.218%0.18240%0.401CS..Hα-helixtrans-59.4-48.8171.8-79.5175.1158.100110.8L85 E91 G92 E93 P105 L106L85-E89 WeakPolarHBondContact O-CB 3.26Å; L85-E89 VanDerWaalsContact O-CG 3.32Å; L85-E89 WeakPolarHBondContact O-CG 3.47Å; L85-E89 PolarHBondContact O-N 2.93Å; E89-E91 VanDerWaalsContact C-N 3.33Å; E89-E91 PolarHBondContact O-N 2.87Å; E89-G92 PolarHBondContact O-N 3.42Å; E89-E93 WeakPolarHBondContact O-CB 3.3Å; E89-E93 PolarHBondContact O-N 3.04Å; E89-P105 VanDerWaalsContact OE1-CA 3.25Å; E89-P105 WeakPolarHBondContact OE1-CA 3.41Å; E89-L106 HydrophobicContact CG-CB 3.9Å; E89-L106 HydrophobicContact CG-CD1 3.73Å; E89-L106 HydrophobicContact CG-CG 3.58Å; E89-L106 PolarHBondContact OE1-N 2.88Å
90R92.1Very high90.5Very high135 Ų13576.1 Ų76.151%0.50939%0.386SS..Hα-helixtrans-61.8-40.2177.3-69.5177.6-170.4-160.16.9112.4E86 L87 L94E86-R90 WeakPolarHBondContact O-CG 3.45Å; E86-R90 PolarHBondContact O-N 2.91Å; E86-R90 IonicContact OE1-CZ 2.76Å; E86-R90 IonicContact OE1-NE 3.41Å; E86-R90 IonicContact OE1-NH2 3.79Å; E86-R90 PolarHBondContact OE1-NH2 3.17Å; L87-R90 PolarHBondContact O-N 3.17Å; R90-L94 VanDerWaalsContact O-CB 3.22Å; R90-L94 WeakPolarHBondContact O-CB 3.36Å; R90-L94 WeakPolarHBondContact O-CG 3.32Å; R90-L94 PolarHBondContact O-N 3.3Å
91E91.5Very high90.6Very high60 Ų6072.2 Ų72.228%0.2837%0.371SS..Hα-helixtrans-61.2-51.1174-178.3-178.3178.700110.5R83 L87 L88 E89 E93 E95R83-E91 IonicContact NH2-OE1 3.67Å; R83-E91 IonicContact NH2-OE2 3.83Å; R83-E91 PolarHBondContact NH2-OE2 3.44Å; L87-E91 WeakPolarHBondContact O-CB 3.43Å; L87-E91 PolarHBondContact O-N 2.89Å; L88-E91 PolarHBondContact O-N 3.34Å; E89-E91 VanDerWaalsContact C-N 3.33Å; E89-E91 PolarHBondContact O-N 2.87Å; E91-E93 VanDerWaalsContact C-N 3.35Å; E91-E93 PolarHBondContact O-N 3.29Å; E91-E95 WeakPolarHBondContact O-CA 3.37Å; E91-E95 VanDerWaalsContact O-CB 3.24Å; E91-E95 WeakPolarHBondContact O-CB 3.46Å; E91-E95 PolarHBondContact O-N 2.85Å
92G90.8Very high90.8Very high0 Ų077.9 Ų77.90%038%0.379CS..Iπ-helixtrans-61.5-39178.700000113.7L88 E89 H96 G97 F98L88-G92 PolarHBondContact O-N 2.94Å; E89-G92 PolarHBondContact O-N 3.42Å; G92-H96 CarbonylContact O-C 3.58Å; G92-G97 PolarHBondContact O-N 3.06Å; G92-F98 PolarHBondContact O-N 3.23Å
93E88.8Confident91.2Very high116 Ų11671.9 Ų71.954%0.54235%0.347SS..Iπ-helixtrans-74.7-53.8179-171.7178.7-169.100112E89 E91 G97E89-E93 WeakPolarHBondContact O-CB 3.3Å; E89-E93 PolarHBondContact O-N 3.04Å; E91-E93 VanDerWaalsContact C-N 3.35Å; E91-E93 PolarHBondContact O-N 3.29Å; E93-G97 WeakPolarHBondContact O-CA 3.38Å; E93-G97 PolarHBondContact O-N 3.41Å
94L87Confident91.5Very high141 Ų14167.4 Ų67.474%0.73833%0.33SS*.Iπ-helixtrans-82.4-36.4-170-62174.1000113.6R90R90-L94 VanDerWaalsContact O-CB 3.22Å; R90-L94 WeakPolarHBondContact O-CB 3.36Å; R90-L94 WeakPolarHBondContact O-CG 3.32Å; R90-L94 PolarHBondContact O-N 3.3Å
95E87.4Confident91.6Very high141 Ų14166 Ų6666%0.65933%0.326SS*.Iπ-helixtrans-92.8-35-174.4-54.8-171.2-168.100111.9E91E91-E95 WeakPolarHBondContact O-CA 3.37Å; E91-E95 VanDerWaalsContact O-CB 3.24Å; E91-E95 WeakPolarHBondContact O-CB 3.46Å; E91-E95 PolarHBondContact O-N 2.85Å
96H86.4Confident91.6Very high90 Ų9064.6 Ų64.642%0.41732%0.318SS..Iπ-helixtrans-114.1-22.1-172.2-60.7-63.9000114.7G92 F98G92-H96 CarbonylContact O-C 3.58Å; H96-F98 VanDerWaalsContact C-N 3.26Å; H96-F98 HydrophobicContact CB-CB 4.45Å; H96-F98 HydrophobicContact CB-CD1 3.78Å; H96-F98 HydrophobicContact CB-CD2 3.32Å; H96-F98 HydrophobicContact CB-CE1 3.8Å; H96-F98 HydrophobicContact CB-CE2 3.31Å; H96-F98 HydrophobicContact CB-CG 3.57Å; H96-F98 HydrophobicContact CB-CZ 3.58Å; H96-F98 AromaticContact CD2-CE2 3.66Å; H96-F98 AromaticContact CG-CD2 3.81Å; H96-F98 AromaticContact CG-CE2 3.37Å; H96-F98 AromaticContact CG-CZ 3.76Å; H96-F98 AromaticContact ND1-CE2 4Å; H96-F98 PolarHBondContact O-N 2.84Å
97G91.9Very high91.6Very high35 Ų3561.3 Ų61.336%0.36130%0.302SS..  trans65.927.2-173.400000113.5G92 E93 G99 Q150G92-G97 PolarHBondContact O-N 3.06Å; E93-G97 WeakPolarHBondContact O-CA 3.38Å; E93-G97 PolarHBondContact O-N 3.41Å; G97-G99 PolarHBondContact O-N 2.76Å; G97-G99 VanDerWaalsContact O-N 3.09Å; G97-Q150 PolarHBondContact O-NE2 3.27Å
98F95.2Very high91.5Very high9 Ų960.7 Ų60.74%0.03931%0.306CS..  trans-70.71.6-176.7-70.1-29.5000114.7D70 Y71 F74 G92 H96 V100 S149 Q150 A151D70-F98 HydrophobicContact CB-CZ 4.37Å; Y71-F98 HydrophobicContact CD2-CB 3.95Å; Y71-F98 AromaticContact CD2-CD1 3.74Å; Y71-F98 HydrophobicContact CD2-CD1 3.74Å; Y71-F98 HydrophobicContact CD2-CD2 4.38Å; Y71-F98 HydrophobicContact CD2-CE1 4.28Å; Y71-F98 AromaticContact CD2-CG 3.78Å; Y71-F98 HydrophobicContact CD2-CG 3.78Å; Y71-F98 HydrophobicContact CE2-CB 4.06Å; Y71-F98 HydrophobicContact CE2-CG 4.4Å; F74-F98 HydrophobicContact CB-CD2 3.79Å; F74-F98 HydrophobicContact CB-CE2 3.49Å; F74-F98 VanDerWaalsContact CB-CE2 3.49Å; F74-F98 HydrophobicContact CB-CZ 4.42Å; F74-F98 HydrophobicContact CD1-CB 4.43Å; F74-F98 AromaticContact CD1-CD2 3.57Å; F74-F98 HydrophobicContact CD1-CD2 3.57Å; F74-F98 HydrophobicContact CD1-CE2 4.21Å; F74-F98 HydrophobicContact CD1-CG 4.36Å; F74-F98 AromaticContact CD2-CD2 3.72Å; F74-F98 HydrophobicContact CD2-CD2 3.72Å; F74-F98 AromaticContact CD2-CE2 3.88Å; F74-F98 HydrophobicContact CD2-CE2 3.88Å; F74-F98 HydrophobicContact CE1-CB 4.45Å; F74-F98 HydrophobicContact CE1-CD2 4.1Å; F74-F98 HydrophobicContact CE2-CD2 4.21Å; F74-F98 AromaticContact CG-CD2 3.38Å; F74-F98 HydrophobicContact CG-CD2 3.38Å; F74-F98 AromaticContact CG-CE2 3.58Å; F74-F98 HydrophobicContact CG-CE2 3.58Å; F74-F98 HydrophobicContact CZ-CD2 4.4Å; G92-F98 PolarHBondContact O-N 3.23Å; H96-F98 VanDerWaalsContact C-N 3.26Å; H96-F98 HydrophobicContact CB-CB 4.45Å; H96-F98 HydrophobicContact CB-CD1 3.78Å; H96-F98 HydrophobicContact CB-CD2 3.32Å; H96-F98 HydrophobicContact CB-CE1 3.8Å; H96-F98 HydrophobicContact CB-CE2 3.31Å; H96-F98 HydrophobicContact CB-CG 3.57Å; H96-F98 HydrophobicContact CB-CZ 3.58Å; H96-F98 AromaticContact CD2-CE2 3.66Å; H96-F98 AromaticContact CG-CD2 3.81Å; H96-F98 AromaticContact CG-CE2 3.37Å; H96-F98 AromaticContact CG-CZ 3.76Å; H96-F98 AromaticContact ND1-CE2 4Å; H96-F98 PolarHBondContact O-N 2.84Å; F98-V100 VanDerWaalsContact C-N 3.27Å; F98-V100 PolarHBondContact O-N 2.75Å; F98-S149 WeakPolarHBondContact CD1-O 3.44Å; F98-Q150 CarbonylContact O-C 3.45Å; F98-Q150 WeakPolarHBondContact O-CA 3.44Å; F98-A151 PolarHBondContact O-N 3.29Å
99G94.3Very high91.5Very high19 Ų1961.8 Ų61.820%0.19631%0.314CS..  trans68.224.8172.100000114.1G97 C104G97-G99 PolarHBondContact O-N 2.76Å; G97-G99 VanDerWaalsContact O-N 3.09Å; G99-C104 WeakPolarHBondContact O-CB 3.36Å
100V93.5Very high91.6Very high3 Ų359.9 Ų59.92%0.01831%0.305CS..  trans-92.9153.6173.1-64.60000110.7F74 L75 F98 C104 L106 A151F74-V100 HydrophobicContact CE1-CB 4.42Å; F74-V100 HydrophobicContact CE1-CG1 3.9Å; F74-V100 HydrophobicContact CE1-CG2 3.77Å; F74-V100 HydrophobicContact CZ-CG2 3.72Å; L75-V100 HydrophobicContact CD2-CG1 4.32Å; F98-V100 VanDerWaalsContact C-N 3.27Å; F98-V100 PolarHBondContact O-N 2.75Å; V100-C104 WeakPolarHBondContact CA-O 3.33Å; V100-L106 HydrophobicContact CB-CD2 4.15Å; V100-L106 HydrophobicContact CB-CG 4.3Å; V100-L106 HydrophobicContact CG1-CD2 3.9Å; V100-A151 HydrophobicContact CG1-CB 4.13Å
101G89.7Confident91.9Very high10 Ų1054.7 Ų54.710%0.10329%0.286CS..BIsolated β-bridgetrans100.6173-167.200000111.9D103 C104G101-D103 PolarHBondContact O-N 3.17Å; G101-C104 PolarHBondContact N-O 3.48Å; G101-C104 CarbonylContact O-C 3.46Å; G101-C104 PolarHBondContact O-N 2.79Å
102Y89.5Confident92.1Very high233 Ų23353.7 Ų53.791%0.91429%0.288SS*.THydrogen-bonded Turntrans46.4-94.8-178.1-168-112.5000115.1
103D91.5Very high92.4Very high45 Ų4554.1 Ų54.124%0.24129%0.29CS..THydrogen-bonded Turntrans-80.5-21.6178.564.1-35.9000112.8G101 P105 G153 F154G101-D103 PolarHBondContact O-N 3.17Å; D103-P105 VanDerWaalsContact O-CD 3.29Å; D103-P105 WeakPolarHBondContact O-CD 3.34Å; D103-G153 WeakPolarHBondContact OD2-CA 3.32Å; D103-G153 PolarHBondContact OD2-N 2.79Å; D103-F154 HydrophobicContact CB-CE1 4.25Å; D103-F154 WeakPolarHBondContact O-CD1 3.49Å; D103-F154 WeakPolarHBondContact O-CE1 3.39Å
104C94.6Very high92.8Very high0 Ų048.9 Ų48.90%027%0.267CS..BIsolated β-bridgetrans-118.561.8176.4-77.40000112.3G99 V100 G101 A151 F154 Y156G99-C104 WeakPolarHBondContact O-CB 3.36Å; V100-C104 WeakPolarHBondContact CA-O 3.33Å; G101-C104 PolarHBondContact N-O 3.48Å; G101-C104 CarbonylContact O-C 3.46Å; G101-C104 PolarHBondContact O-N 2.79Å; C104-A151 HydrophobicContact CB-CB 3.79Å; C104-F154 PolarHBondContact SG-N 2.96Å; C104-F154 VanDerWaalsContact SG-N 3.37Å; C104-Y156 WeakPolarHBondContact CA-OH 3.27Å; C104-Y156 HydrophobicContact CB-CE1 3.76Å; C104-Y156 PolarHBondContact O-OH 2.79Å
105P93.8Very high93.4Very high55 Ų5542.4 Ų42.436%0.35723%0.233SC..  trans-68.5137.618030.9-35.7000112.2E89 D103 F107 Y156E89-P105 VanDerWaalsContact OE1-CA 3.25Å; E89-P105 WeakPolarHBondContact OE1-CA 3.41Å; D103-P105 VanDerWaalsContact O-CD 3.29Å; D103-P105 WeakPolarHBondContact O-CD 3.34Å; P105-F107 WeakPolarHBondContact O-CD1 3.33Å; P105-Y156 PolarHBondContact O-OH 3.23Å
106L94.2Very high93.9Very high12 Ų1235.9 Ų35.96%0.06320%0.203CC..  trans-71.2137.3173.9-62.3-175.5000110.8F74 L75 L85 L88 E89 V100 L110F74-L106 HydrophobicContact CE1-CD1 4.44Å; F74-L106 HydrophobicContact CZ-CD1 4.17Å; L75-L106 HydrophobicContact CD2-CD2 4.29Å; L85-L106 HydrophobicContact CB-CB 4.34Å; L85-L106 HydrophobicContact CD2-CB 4.25Å; L88-L106 HydrophobicContact CB-CD1 4.07Å; L88-L106 HydrophobicContact CD2-CD1 3.67Å; L88-L106 HydrophobicContact CG-CD1 3.7Å; E89-L106 HydrophobicContact CG-CB 3.9Å; E89-L106 HydrophobicContact CG-CD1 3.73Å; E89-L106 HydrophobicContact CG-CG 3.58Å; E89-L106 PolarHBondContact OE1-N 2.88Å; V100-L106 HydrophobicContact CB-CD2 4.15Å; V100-L106 HydrophobicContact CB-CG 4.3Å; V100-L106 HydrophobicContact CG1-CD2 3.9Å; L106-L110 HydrophobicContact CD2-CD2 3.39Å
107F92.6Very high94.5Very high38 Ų3831.6 Ų31.617%0.16718%0.183CC..  trans-136155.4171.655.2-86.3000110.3V27 P105 S109 L110 Y113 Y156V27-F107 HydrophobicContact CG2-CE2 4.24Å; V27-F107 HydrophobicContact CG2-CZ 3.8Å; P105-F107 WeakPolarHBondContact O-CD1 3.33Å; F107-S109 WeakPolarHBondContact CD2-OG 3.39Å; F107-S109 PolarHBondContact O-N 3.4Å; F107-S109 VanDerWaalsContact O-N 3.15Å; F107-L110 HydrophobicContact CD1-CB 4.16Å; F107-L110 HydrophobicContact CD1-CD1 4.2Å; F107-L110 HydrophobicContact CD2-CB 3.99Å; F107-L110 VanDerWaalsContact CD2-N 3.35Å; F107-L110 HydrophobicContact CE1-CB 4.07Å; F107-L110 HydrophobicContact CE1-CD1 3.43Å; F107-L110 VanDerWaalsContact CE1-CD1 3.43Å; F107-L110 HydrophobicContact CE1-CG 4.31Å; F107-L110 HydrophobicContact CE2-CB 3.91Å; F107-L110 HydrophobicContact CE2-CD1 4.3Å; F107-L110 HydrophobicContact CG-CB 4.11Å; F107-L110 HydrophobicContact CZ-CB 3.93Å; F107-L110 HydrophobicContact CZ-CD1 3.48Å; F107-L110 VanDerWaalsContact CZ-CD1 3.48Å; F107-L110 HydrophobicContact CZ-CG 4.34Å; F107-L110 WeakPolarHBondContact O-CB 3.48Å; F107-L110 PolarHBondContact O-N 2.68Å; F107-Y113 HydrophobicContact CE2-CD1 4.36Å; F107-Y113 AromaticContact CZ-CD1 3.85Å; F107-Y113 HydrophobicContact CZ-CD1 3.85Å; F107-Y113 HydrophobicContact CZ-CE1 4.4Å; F107-Y113 HydrophobicContact CZ-CG 4.44Å; F107-Y156 HydrophobicContact CE1-CE2 4.36Å
108S90.3Very high94.8Very high92 Ų9230 Ų3064%0.64317%0.166SC*.THydrogen-bonded Turntrans-59.3-33.4-169.255.50000114.1S79S79-S108 PolarHBondContact OG-O 3.01Å
109S93.9Very high95Very high24 Ų2429.7 Ų29.717%0.16817%0.165CC..THydrogen-bonded Turntrans-90.14.1178.353.30000114.1T26 F107 Y111 A112 Y113T26-S109 WeakPolarHBondContact CB-OG 3.39Å; T26-S109 PolarHBondContact OG1-OG 2.77Å; F107-S109 WeakPolarHBondContact CD2-OG 3.39Å; F107-S109 PolarHBondContact O-N 3.4Å; F107-S109 VanDerWaalsContact O-N 3.15Å; S109-Y111 PolarHBondContact O-N 2.91Å; S109-A112 PolarHBondContact O-N 3.47Å; S109-Y113 WeakPolarHBondContact O-CB 3.4Å; S109-Y113 PolarHBondContact O-N 3.45Å
110L95.2Very high95.2Very high0 Ų028.8 Ų28.80%016%0.156CC..Hα-helixtrans-53.5-53.3-172.7173.867.3000113L75 L106 F107 A112 Y113 G114 Y156L75-L110 HydrophobicContact CD2-CD2 4.03Å; L106-L110 HydrophobicContact CD2-CD2 3.39Å; F107-L110 HydrophobicContact CD1-CB 4.16Å; F107-L110 HydrophobicContact CD1-CD1 4.2Å; F107-L110 HydrophobicContact CD2-CB 3.99Å; F107-L110 VanDerWaalsContact CD2-N 3.35Å; F107-L110 HydrophobicContact CE1-CB 4.07Å; F107-L110 HydrophobicContact CE1-CD1 3.43Å; F107-L110 VanDerWaalsContact CE1-CD1 3.43Å; F107-L110 HydrophobicContact CE1-CG 4.31Å; F107-L110 HydrophobicContact CE2-CB 3.91Å; F107-L110 HydrophobicContact CE2-CD1 4.3Å; F107-L110 HydrophobicContact CG-CB 4.11Å; F107-L110 HydrophobicContact CZ-CB 3.93Å; F107-L110 HydrophobicContact CZ-CD1 3.48Å; F107-L110 VanDerWaalsContact CZ-CD1 3.48Å; F107-L110 HydrophobicContact CZ-CG 4.34Å; F107-L110 WeakPolarHBondContact O-CB 3.48Å; F107-L110 PolarHBondContact O-N 2.68Å; L110-A112 PolarHBondContact O-N 3.4Å; L110-Y113 PolarHBondContact O-N 3.04Å; L110-G114 PolarHBondContact O-N 2.69Å; L110-Y156 HydrophobicContact CD1-CD1 3.76Å; L110-Y156 HydrophobicContact CD1-CD2 3.45Å; L110-Y156 VanDerWaalsContact CD1-CD2 3.45Å; L110-Y156 HydrophobicContact CD1-CE1 3.79Å; L110-Y156 HydrophobicContact CD1-CE2 3.49Å; L110-Y156 VanDerWaalsContact CD1-CE2 3.49Å; L110-Y156 HydrophobicContact CD1-CG 3.59Å; L110-Y156 HydrophobicContact CD2-CD1 3.75Å; L110-Y156 HydrophobicContact CD2-CE1 3.73Å; L110-Y156 HydrophobicContact CD2-CG 4.35Å; L110-Y156 HydrophobicContact CG-CD1 4.31Å; L110-Y156 HydrophobicContact CG-CE1 4.42Å; L110-Y156 HydrophobicContact CG-CG 4.44Å
111Y96.8Very high95.5Very high26 Ų2628.6 Ų28.610%0.10216%0.155CC..Hα-helixtrans-65-42.8-177.6-168.3-98.3000111.5K60 L63 V72 L75 H76 S79 S109 Y113 G114 T115 F157K60-Y111 WeakPolarHBondContact CG-OH 3.37Å; L63-Y111 HydrophobicContact CD1-CE2 4.42Å; V72-Y111 HydrophobicContact CG1-CE2 4.4Å; L75-Y111 HydrophobicContact CB-CD2 4.14Å; H76-Y111 HydrophobicContact CB-CD2 3.9Å; H76-Y111 HydrophobicContact CB-CE1 4.41Å; H76-Y111 HydrophobicContact CB-CE2 3.61Å; H76-Y111 HydrophobicContact CB-CG 4.38Å; H76-Y111 AromaticContact CD2-CD1 3.81Å; H76-Y111 AromaticContact CD2-CE1 3.54Å; H76-Y111 AromaticContact CD2-CZ 3.81Å; S79-Y111 WeakPolarHBondContact OG-CB 3.44Å; S109-Y111 PolarHBondContact O-N 2.91Å; Y111-Y113 PolarHBondContact O-N 2.98Å; Y111-G114 PolarHBondContact O-N 2.89Å; Y111-T115 HydrophobicContact CD1-CG2 3.87Å; Y111-T115 HydrophobicContact CD2-CG2 4.2Å; Y111-T115 HydrophobicContact CE1-CG2 3.54Å; Y111-T115 HydrophobicContact CE2-CG2 3.93Å; Y111-T115 HydrophobicContact CG-CG2 4.18Å; Y111-T115 WeakPolarHBondContact O-CB 3.35Å; Y111-T115 VanDerWaalsContact O-CG2 3.25Å; Y111-T115 WeakPolarHBondContact O-CG2 3.31Å; Y111-T115 PolarHBondContact O-N 3.48Å; Y111-T115 PolarHBondContact O-OG1 3.18Å; Y111-F157 HydrophobicContact CD2-CE2 4.34Å; Y111-F157 HydrophobicContact CD2-CZ 4.03Å; Y111-F157 AromaticContact CE2-CZ 3.94Å; Y111-F157 HydrophobicContact CE2-CZ 3.94Å
112A97.3Very high95.9Very high39 Ų3928.6 Ų28.632%0.32215%0.152SC..Hα-helixtrans-61.9-44.2177.400000112.1L23 S109 L110 T115 L116L23-A112 HydrophobicContact CD1-CB 4.41Å; L23-A112 HydrophobicContact CD2-CB 4.06Å; S109-A112 PolarHBondContact O-N 3.47Å; L110-A112 PolarHBondContact O-N 3.4Å; A112-T115 PolarHBondContact O-OG1 3.37Å; A112-L116 VanDerWaalsContact O-CB 3.27Å; A112-L116 WeakPolarHBondContact O-CB 3.32Å; A112-L116 PolarHBondContact O-N 2.81Å; A112-L116 VanDerWaalsContact O-N 3.16Å
113Y96.8Very high96.3Very high8 Ų819.9 Ų19.93%0.03112%0.12CC..Hα-helixtrans-60.6-56.5173.9157.9-103.3000111.3C24 V27 F107 S109 L110 Y111 T115 L116 V117 W143C24-Y113 HydrophobicContact CB-CE2 4.26Å; V27-Y113 HydrophobicContact CG2-CD1 4.04Å; V27-Y113 HydrophobicContact CG2-CD2 3.94Å; V27-Y113 HydrophobicContact CG2-CE1 3.83Å; V27-Y113 HydrophobicContact CG2-CE2 3.72Å; V27-Y113 HydrophobicContact CG2-CG 4.08Å; F107-Y113 HydrophobicContact CE2-CD1 4.36Å; F107-Y113 AromaticContact CZ-CD1 3.85Å; F107-Y113 HydrophobicContact CZ-CD1 3.85Å; F107-Y113 HydrophobicContact CZ-CE1 4.4Å; F107-Y113 HydrophobicContact CZ-CG 4.44Å; S109-Y113 WeakPolarHBondContact O-CB 3.4Å; S109-Y113 PolarHBondContact O-N 3.45Å; L110-Y113 PolarHBondContact O-N 3.04Å; Y111-Y113 PolarHBondContact O-N 2.98Å; Y113-T115 PolarHBondContact O-N 2.96Å; Y113-L116 PolarHBondContact O-N 3.36Å; Y113-V117 HydrophobicContact CD2-CG2 3.92Å; Y113-V117 HydrophobicContact CE2-CG2 3.58Å; Y113-V117 WeakPolarHBondContact O-CG2 3.23Å; Y113-V117 PolarHBondContact O-N 2.84Å; Y113-W143 WeakPolarHBondContact OH-CZ2 3.47Å; Y113-W143 PolarHBondContact OH-NE1 2.88Å
114G97.5Very high96.7Very high6 Ų617.8 Ų17.86%0.06211%0.109CC..Hα-helixtrans-62.3-43.1-173.900000112.4L110 Y111 T118L110-G114 PolarHBondContact O-N 2.69Å; Y111-G114 PolarHBondContact O-N 2.89Å; G114-T118 VanDerWaalsContact O-CB 3.25Å; G114-T118 WeakPolarHBondContact O-CB 3.37Å; G114-T118 PolarHBondContact O-N 2.89Å; G114-T118 PolarHBondContact O-OG1 3.27Å
115T98.4Very high96.9Very high5 Ų517.8 Ų17.83%0.03111%0.109CC..Hα-helixtrans-69.5-36177.558.50000112.8S57 A58 L63 Y111 A112 Y113 G119 F157S57-T115 WeakPolarHBondContact CA-O 3.19Å; A58-T115 PolarHBondContact N-O 3.41Å; L63-T115 HydrophobicContact CD1-CG2 3.72Å; Y111-T115 HydrophobicContact CD1-CG2 3.87Å; Y111-T115 HydrophobicContact CD2-CG2 4.2Å; Y111-T115 HydrophobicContact CE1-CG2 3.54Å; Y111-T115 HydrophobicContact CE2-CG2 3.93Å; Y111-T115 HydrophobicContact CG-CG2 4.18Å; Y111-T115 WeakPolarHBondContact O-CB 3.35Å; Y111-T115 VanDerWaalsContact O-CG2 3.25Å; Y111-T115 WeakPolarHBondContact O-CG2 3.31Å; Y111-T115 PolarHBondContact O-N 3.48Å; Y111-T115 PolarHBondContact O-OG1 3.18Å; A112-T115 PolarHBondContact O-OG1 3.37Å; Y113-T115 PolarHBondContact O-N 2.96Å; T115-G119 PolarHBondContact O-N 3.29Å; T115-F157 HydrophobicContact CG2-CE2 4.29Å
116L98.7Very high97.1Very high4 Ų416.8 Ų16.82%0.02110%0.101CC..Hα-helixtrans-69.7-42.2177.3-174.860000112.1Q19 L20 L23 P55 A112 Y113 A120Q19-L116 HydrophobicContact CG-CD2 4.3Å; L20-L116 HydrophobicContact CB-CD2 4.04Å; L20-L116 HydrophobicContact CD1-CD2 4.08Å; L20-L116 HydrophobicContact CD1-CG 3.98Å; L23-L116 HydrophobicContact CD1-CB 4.43Å; L23-L116 HydrophobicContact CD1-CD2 3.6Å; P55-L116 HydrophobicContact CB-CD1 4.34Å; P55-L116 HydrophobicContact CG-CD1 4.16Å; A112-L116 VanDerWaalsContact O-CB 3.27Å; A112-L116 WeakPolarHBondContact O-CB 3.32Å; A112-L116 PolarHBondContact O-N 2.81Å; A112-L116 VanDerWaalsContact O-N 3.16Å; Y113-L116 PolarHBondContact O-N 3.36Å; L116-A120 WeakPolarHBondContact O-CB 3.47Å; L116-A120 PolarHBondContact O-N 3.35Å
117V98.6Very high97.4Very high0 Ų017.1 Ų17.10%010%0.102CC..Hα-helixtrans-62.2-46.7174168.90000110.8L20 Y113 A120 S121 N138 C140L20-V117 HydrophobicContact CD1-CG2 4.04Å; Y113-V117 HydrophobicContact CD2-CG2 3.92Å; Y113-V117 HydrophobicContact CE2-CG2 3.58Å; Y113-V117 WeakPolarHBondContact O-CG2 3.23Å; Y113-V117 PolarHBondContact O-N 2.84Å; V117-A120 WeakPolarHBondContact O-CB 3.25Å; V117-A120 PolarHBondContact O-N 3.41Å; V117-S121 PolarHBondContact O-N 3.1Å; V117-N138 PolarHBondContact O-ND2 3.46Å; V117-C140 WeakPolarHBondContact CG1-O 3.32Å; V117-C140 HydrophobicContact CG2-CB 4.11Å
118T98.8Very high97.7Very high2 Ų215.3 Ų15.31%0.0129%0.094CC..Hα-helixtrans-65-44.9-179.8-580000111.7A58 L63 G114 A120 S121 I122 F157 D159 L162A58-T118 HydrophobicContact CB-CG2 4.15Å; L63-T118 HydrophobicContact CD2-CG2 3.77Å; G114-T118 VanDerWaalsContact O-CB 3.25Å; G114-T118 WeakPolarHBondContact O-CB 3.37Å; G114-T118 PolarHBondContact O-N 2.89Å; G114-T118 PolarHBondContact O-OG1 3.27Å; T118-A120 VanDerWaalsContact C-N 3.28Å; T118-A120 PolarHBondContact O-N 3.4Å; T118-S121 PolarHBondContact O-N 2.78Å; T118-S121 VanDerWaalsContact O-N 3.11Å; T118-I122 HydrophobicContact CG2-CD1 4.03Å; T118-I122 WeakPolarHBondContact O-CG1 3.32Å; T118-I122 PolarHBondContact O-N 2.96Å; T118-F157 WeakPolarHBondContact OG1-CB 3.46Å; T118-D159 HydrophobicContact CG2-CB 4.17Å; T118-L162 HydrophobicContact CG2-CD1 3.41Å; T118-L162 VanDerWaalsContact CG2-CD1 3.41Å
119G98.8Very high98.1Very high2 Ų211.6 Ų11.62%0.0217%0.067CC..Hα-helixtrans-62-36.6177.100000112.2T56 T115 S121 I122 Q123T56-G119 CarbonylContact O-C 3.58Å; T56-G119 VanDerWaalsContact O-CA 3.31Å; T56-G119 WeakPolarHBondContact O-CA 3.5Å; T115-G119 PolarHBondContact O-N 3.29Å; G119-S121 PolarHBondContact O-N 2.87Å; G119-I122 PolarHBondContact O-N 3.5Å; G119-Q123 WeakPolarHBondContact O-CB 3.42Å; G119-Q123 VanDerWaalsContact O-CG 3.25Å; G119-Q123 WeakPolarHBondContact O-CG 3.45Å; G119-Q123 PolarHBondContact O-N 3.33Å; G119-Q123 PolarHBondContact O-OE1 2.81Å
120A98.9Very high98.3Very high0 Ų016.5 Ų16.50%09%0.086CC..Hα-helixtrans-59.1-44.9171.800000112.5A15 P55 L116 V117 T118 Q123 C124A15-A120 HydrophobicContact CB-CB 3.99Å; P55-A120 HydrophobicContact CB-CB 3.46Å; P55-A120 VanDerWaalsContact CB-CB 3.46Å; P55-A120 HydrophobicContact CG-CB 3.96Å; L116-A120 WeakPolarHBondContact O-CB 3.47Å; L116-A120 PolarHBondContact O-N 3.35Å; V117-A120 WeakPolarHBondContact O-CB 3.25Å; V117-A120 PolarHBondContact O-N 3.41Å; T118-A120 VanDerWaalsContact C-N 3.28Å; T118-A120 PolarHBondContact O-N 3.4Å; A120-Q123 PolarHBondContact O-N 2.86Å; A120-C124 WeakPolarHBondContact O-CB 3.4Å; A120-C124 PolarHBondContact O-N 3.28Å; A120-C124 PolarHBondContact O-SG 2.85Å
121S98.9Very high98.4Very high0 Ų019 Ų190%011%0.112CC..Hα-helixtrans-65.4-42.1176.6-640000112.6V117 T118 G119 C124 A125 N138 D159 L305V117-S121 PolarHBondContact O-N 3.1Å; T118-S121 PolarHBondContact O-N 2.78Å; T118-S121 VanDerWaalsContact O-N 3.11Å; G119-S121 PolarHBondContact O-N 2.87Å; S121-C124 WeakPolarHBondContact O-CB 3.44Å; S121-C124 PolarHBondContact O-N 3.22Å; S121-A125 PolarHBondContact O-N 2.99Å; S121-N138 PolarHBondContact N-ND2 3.43Å; S121-N138 PolarHBondContact OG-ND2 3.43Å; S121-D159 WeakPolarHBondContact CB-OD2 3.38Å; S121-D159 PolarHBondContact OG-OD2 3.41Å; S121-L305 WeakPolarHBondContact OG-CD2 3.42Å
122I98.9Very high98.5Very high9 Ų922 Ų225%0.04613%0.127CC..Hα-helixtrans-62.1-44.4175.9-66.1171000110.5A58 E62 T118 G119 A125 D126 L162 K166A58-I122 HydrophobicContact CB-CD1 4.16Å; E62-I122 HydrophobicContact CB-CD1 4.03Å; T118-I122 HydrophobicContact CG2-CD1 4.03Å; T118-I122 WeakPolarHBondContact O-CG1 3.32Å; T118-I122 PolarHBondContact O-N 2.96Å; G119-I122 PolarHBondContact O-N 3.5Å; I122-A125 WeakPolarHBondContact O-CB 3.48Å; I122-A125 PolarHBondContact O-N 2.88Å; I122-D126 WeakPolarHBondContact O-CB 3.29Å; I122-D126 PolarHBondContact O-N 2.92Å; I122-L162 HydrophobicContact CD1-CB 4.19Å; I122-L162 HydrophobicContact CD1-CD1 4.49Å; I122-L162 HydrophobicContact CG1-CB 4.13Å; I122-K166 HydrophobicContact CG2-CD 4.43Å; I122-K166 HydrophobicContact CG2-CG 4.19Å
123Q98.9Very high98.5Very high51 Ų5120.6 Ų20.624%0.23811%0.114CC..Hα-helixtrans-66.1-38.3176.9-72.9176.8-51.900112.4F53 T56 G119 A120 A125 D126 L127F53-Q123 HydrophobicContact CE2-CB 3.93Å; F53-Q123 HydrophobicContact CZ-CB 4.29Å; T56-Q123 PolarHBondContact OG1-NE2 3.44Å; G119-Q123 WeakPolarHBondContact O-CB 3.42Å; G119-Q123 VanDerWaalsContact O-CG 3.25Å; G119-Q123 WeakPolarHBondContact O-CG 3.45Å; G119-Q123 PolarHBondContact O-N 3.33Å; G119-Q123 PolarHBondContact O-OE1 2.81Å; A120-Q123 PolarHBondContact O-N 2.86Å; Q123-A125 VanDerWaalsContact C-N 3.31Å; Q123-A125 PolarHBondContact O-N 2.85Å; Q123-D126 PolarHBondContact O-N 2.79Å; Q123-L127 WeakPolarHBondContact O-CG 3.35Å; Q123-L127 PolarHBondContact O-N 2.87Å
124C98.9Very high98.6Very high0 Ų025.1 Ų25.10%013%0.134CC..Hα-helixtrans-59.4-42.5172.1-78.70000111.7F53 A120 S121 L128 S136 L303F53-C124 VanDerWaalsContact CZ-SG 3.56Å; A120-C124 WeakPolarHBondContact O-CB 3.4Å; A120-C124 PolarHBondContact O-N 3.28Å; A120-C124 PolarHBondContact O-SG 2.85Å; S121-C124 WeakPolarHBondContact O-CB 3.44Å; S121-C124 PolarHBondContact O-N 3.22Å; C124-L128 WeakPolarHBondContact O-CG 3.3Å; C124-L128 PolarHBondContact O-N 3.23Å; C124-S136 VanDerWaalsContact C-OG 3.28Å; C124-S136 WeakPolarHBondContact CB-OG 3.29Å; C124-S136 WeakPolarHBondContact O-CB 3.4Å; C124-S136 PolarHBondContact O-OG 3.4Å; C124-L303 HydrophobicContact CB-CD1 3.38Å
125A98.9Very high98.6Very high0 Ų025 Ų250%013%0.132CC..Hα-helixtrans-65-40.1173.500000112.5S121 I122 Q123 L128 N129 K166 L167 L303S121-A125 PolarHBondContact O-N 2.99Å; I122-A125 WeakPolarHBondContact O-CB 3.48Å; I122-A125 PolarHBondContact O-N 2.88Å; Q123-A125 VanDerWaalsContact C-N 3.31Å; Q123-A125 PolarHBondContact O-N 2.85Å; A125-L128 WeakPolarHBondContact O-CB 3.26Å; A125-L128 PolarHBondContact O-N 2.94Å; A125-N129 PolarHBondContact O-N 3.35Å; A125-K166 HydrophobicContact CB-CB 3.83Å; A125-K166 HydrophobicContact CB-CG 3.79Å; A125-L167 HydrophobicContact CB-CD2 4.05Å; A125-L167 HydrophobicContact CB-CG 3.84Å; A125-L303 HydrophobicContact CB-CD2 4.49Å
126D98.7Very high98.7Very high35 Ų3524.8 Ų24.819%0.18713%0.13CC..Hα-helixtrans-65.3-38.4178.7-170.657.2000112.6I122 Q123 L128 N129 K130 K166I122-D126 WeakPolarHBondContact O-CB 3.29Å; I122-D126 PolarHBondContact O-N 2.92Å; Q123-D126 PolarHBondContact O-N 2.79Å; D126-L128 VanDerWaalsContact C-N 3.3Å; D126-L128 PolarHBondContact O-N 3.3Å; D126-N129 WeakPolarHBondContact O-CB 3.32Å; D126-N129 PolarHBondContact O-N 3.19Å; D126-K130 WeakPolarHBondContact O-CG 3.35Å; D126-K130 PolarHBondContact O-N 2.62Å; D126-K130 WeakPolarHBondContact OD2-CE 3.43Å; D126-K130 IonicContact OD2-NZ 3.91Å; D126-K130 PolarHBondContact OD2-NZ 2.92Å; D126-K166 HydrophobicContact CB-CG 4.47Å; D126-K166 VanDerWaalsContact OD1-CE 3.22Å; D126-K166 WeakPolarHBondContact OD1-CE 3.35Å; D126-K166 IonicContact OD1-NZ 2.77Å
127L98.8Very high98.7Very high19 Ų1924.8 Ų24.810%0.09913%0.13CC..Hα-helixtrans-59.4-39.8172.2-71.3172000112A13 F53 Q123 G131 E132 V133A13-L127 HydrophobicContact CB-CD1 3.85Å; F53-L127 HydrophobicContact CD1-CD1 4Å; F53-L127 HydrophobicContact CE1-CD1 3.77Å; F53-L127 HydrophobicContact CZ-CD1 4.14Å; Q123-L127 WeakPolarHBondContact O-CG 3.35Å; Q123-L127 PolarHBondContact O-N 2.87Å; L127-G131 PolarHBondContact O-N 3.4Å; L127-E132 HydrophobicContact CD2-CB 4.22Å; L127-E132 VanDerWaalsContact CD2-OE2 3.32Å; L127-E132 WeakPolarHBondContact CD2-OE2 3.45Å; L127-E132 PolarHBondContact O-N 2.95Å; L127-V133 HydrophobicContact CB-CG2 3.84Å
128L98.8Very high98.7Very high0 Ų024.8 Ų24.80%013%0.13CC..Hα-helixtrans-69.4-38.4174.8-65.4171.1000111.7C124 A125 D126 K130 G131 V133 K134 S136 L167 Y171 P301 L303C124-L128 WeakPolarHBondContact O-CG 3.3Å; C124-L128 PolarHBondContact O-N 3.23Å; A125-L128 WeakPolarHBondContact O-CB 3.26Å; A125-L128 PolarHBondContact O-N 2.94Å; D126-L128 VanDerWaalsContact C-N 3.3Å; D126-L128 PolarHBondContact O-N 3.3Å; L128-K130 VanDerWaalsContact C-N 3.33Å; L128-G131 PolarHBondContact O-N 3.01Å; L128-G131 VanDerWaalsContact O-N 3.17Å; L128-V133 HydrophobicContact CD2-CG2 3.91Å; L128-V133 HydrophobicContact CG-CG2 4.44Å; L128-K134 WeakPolarHBondContact CD2-O 3.38Å; L128-S136 VanDerWaalsContact CD1-OG 3.3Å; L128-S136 WeakPolarHBondContact CD1-OG 3.47Å; L128-S136 WeakPolarHBondContact CG-OG 3.44Å; L128-L167 HydrophobicContact CB-CD2 3.88Å; L128-L167 HydrophobicContact CD1-CD2 4.07Å; L128-Y171 PolarHBondContact O-OH 2.78Å; L128-P301 HydrophobicContact CB-CB 4.34Å; L128-P301 HydrophobicContact CD2-CB 4.07Å; L128-L303 HydrophobicContact CD1-CB 3.84Å
129N98.7Very high98.7Very high14 Ų1424.7 Ų24.78%0.07513%0.13CC..Hα-helixtrans-63.3-39.8175-80.8-9.9000112.2A125 D126 G131 K166 L167 R170 Y171A125-N129 PolarHBondContact O-N 3.35Å; D126-N129 WeakPolarHBondContact O-CB 3.32Å; D126-N129 PolarHBondContact O-N 3.19Å; N129-G131 PolarHBondContact O-N 3.29Å; N129-K166 PolarHBondContact ND2-O 3.45Å; N129-L167 WeakPolarHBondContact OD1-CA 3.24Å; N129-L167 PolarHBondContact OD1-O 2.96Å; N129-R170 HydrophobicContact CB-CB 4.37Å; N129-R170 WeakPolarHBondContact O-CD 3.2Å; N129-R170 PolarHBondContact O-NE 3.13Å; N129-R170 WeakPolarHBondContact OD1-CB 3.19Å; N129-Y171 WeakPolarHBondContact OD1-CD2 3.33Å; N129-Y171 WeakPolarHBondContact OD1-CE2 3.32Å
130K98.5Very high98.6Very high127 Ų12724.7 Ų24.755%0.55213%0.129SC*.THydrogen-bonded Turntrans-73.2-12.1176.7-69.8168.1175.81690113D126 L128 E132D126-K130 WeakPolarHBondContact O-CG 3.35Å; D126-K130 PolarHBondContact O-N 2.62Å; D126-K130 WeakPolarHBondContact OD2-CE 3.43Å; D126-K130 IonicContact OD2-NZ 3.91Å; D126-K130 PolarHBondContact OD2-NZ 2.92Å; L128-K130 VanDerWaalsContact C-N 3.33Å; K130-E132 HydrophobicContact CB-CG 3.96Å; K130-E132 WeakPolarHBondContact CD-OE1 3.44Å; K130-E132 PolarHBondContact O-N 3.17Å
131G98Very high98.6Very high53 Ų5324.7 Ų24.755%0.54613%0.129SC..THydrogen-bonded Turntrans67.821.4-174.900000112.9L127 L128 N129 V133L127-G131 PolarHBondContact O-N 3.4Å; L128-G131 PolarHBondContact O-N 3.01Å; L128-G131 VanDerWaalsContact O-N 3.17Å; N129-G131 PolarHBondContact O-N 3.29Å; G131-V133 VanDerWaalsContact C-N 3.29Å
132E98Very high98.6Very high89 Ų8924.7 Ų24.742%0.41613%0.13SC..SBendtrans-71.7-27.9178-74.1-173.2-141.400112.3K51 L127 K130K51-E132 IonicContact NZ-OE2 3.78Å; K51-E132 PolarHBondContact NZ-OE2 2.82Å; L127-E132 HydrophobicContact CD2-CB 4.22Å; L127-E132 VanDerWaalsContact CD2-OE2 3.32Å; L127-E132 WeakPolarHBondContact CD2-OE2 3.45Å; L127-E132 PolarHBondContact O-N 2.95Å; K130-E132 HydrophobicContact CB-CG 3.96Å; K130-E132 WeakPolarHBondContact CD-OE1 3.44Å; K130-E132 PolarHBondContact O-N 3.17Å
133V98.4Very high98.5Very high8 Ų825 Ų255%0.04813%0.13CC..  trans-140.1160.8179.6-59.80000110A13 L127 L128 G131 V135A13-V133 HydrophobicContact CB-CB 4.48Å; A13-V133 HydrophobicContact CB-CG1 3.79Å; A13-V133 HydrophobicContact CB-CG2 4.31Å; L127-V133 HydrophobicContact CB-CG2 3.84Å; L128-V133 HydrophobicContact CD2-CG2 3.91Å; L128-V133 HydrophobicContact CG-CG2 4.44Å; G131-V133 VanDerWaalsContact C-N 3.29Å; V133-V135 WeakPolarHBondContact CG2-O 3.45Å
134K98.2Very high98.5Very high104 Ų10422.8 Ų22.845%0.45212%0.12SC..SBendtrans-95.9-29.7171.9-63.8178-177.7136.60111.7L7 D11 L128 P301 C302L7-K134 HydrophobicContact CD2-CB 4.01Å; L7-K134 HydrophobicContact CD2-CD 3.71Å; L7-K134 HydrophobicContact CD2-CG 4.48Å; D11-K134 HydrophobicContact CB-CB 4.32Å; D11-K134 HydrophobicContact CB-CD 4.21Å; D11-K134 HydrophobicContact CB-CG 4.33Å; D11-K134 PolarHBondContact O-N 3Å; D11-K134 WeakPolarHBondContact OD1-CD 3.49Å; D11-K134 WeakPolarHBondContact OD1-CE 3.47Å; D11-K134 IonicContact OD1-NZ 2.8Å; D11-K134 PolarHBondContact OD1-NZ 2.75Å; D11-K134 IonicContact OD2-NZ 2.71Å; L128-K134 WeakPolarHBondContact CD2-O 3.38Å; K134-P301 WeakPolarHBondContact O-CA 3.31Å; K134-C302 PolarHBondContact O-N 3Å
135V98.7Very high98.4Very high3 Ų323.1 Ų23.12%0.01812%0.121CC..EExtended strand (participates in β ladder)trans-129132.7176.5-174.90000109.2L7 D11 V12 A13 V133 I137 L296 C302 L304L7-V135 HydrophobicContact CD1-CG2 3.82Å; D11-V135 PolarHBondContact O-N 3.2Å; V12-V135 CarbonylContact C-O 3.58Å; V12-V135 VanDerWaalsContact CA-O 3.28Å; V12-V135 WeakPolarHBondContact CA-O 3.25Å; V12-V135 HydrophobicContact CG1-CB 4.25Å; V12-V135 HydrophobicContact CG1-CG1 4.35Å; V12-V135 HydrophobicContact CG2-CB 4.24Å; A13-V135 PolarHBondContact N-O 3.39Å; V133-V135 WeakPolarHBondContact CG2-O 3.45Å; V135-I137 HydrophobicContact CG1-CD1 4.49Å; V135-I137 HydrophobicContact CG1-CG1 4.12Å; V135-L296 HydrophobicContact CG2-CD2 3.72Å; V135-C302 CarbonylContact C-O 3.59Å; V135-C302 VanDerWaalsContact CA-O 3.24Å; V135-C302 WeakPolarHBondContact CA-O 3.38Å; V135-C302 HydrophobicContact CG2-CB 4.41Å; V135-L304 HydrophobicContact CG1-CD1 3.86Å; V135-L304 HydrophobicContact CG1-CG 3.95Å
136S98.8Very high98.3Very high0 Ų023.1 Ų23.10%012%0.121CC..EExtended strand (participates in β ladder)trans-125.3145.7169.657.80000109.9A13 C124 L128 C302 L303 L304A13-S136 CarbonylContact O-C 3.55Å; A13-S136 WeakPolarHBondContact O-CA 3.22Å; C124-S136 VanDerWaalsContact C-OG 3.28Å; C124-S136 WeakPolarHBondContact CB-OG 3.29Å; C124-S136 WeakPolarHBondContact O-CB 3.4Å; C124-S136 PolarHBondContact O-OG 3.4Å; L128-S136 VanDerWaalsContact CD1-OG 3.3Å; L128-S136 WeakPolarHBondContact CD1-OG 3.47Å; L128-S136 WeakPolarHBondContact CG-OG 3.44Å; S136-C302 PolarHBondContact N-O 3.39Å; S136-L303 CarbonylContact O-C 3.6Å; S136-L303 WeakPolarHBondContact O-CA 3.41Å; S136-L304 PolarHBondContact O-N 2.93Å
137I98.9Very high98.1Very high4 Ų425.4 Ų25.42%0.02113%0.127CC..EExtended strand (participates in β ladder)trans-132.1124.8-168-51.2179.4000109.9V12 A13 L14 A15 V135 L304 W319 L323V12-I137 HydrophobicContact CG1-CD1 3.78Å; V12-I137 HydrophobicContact CG1-CG1 4.36Å; A13-I137 PolarHBondContact O-N 2.93Å; L14-I137 HydrophobicContact CD1-CB 3.85Å; L14-I137 HydrophobicContact CD1-CG2 3.73Å; A15-I137 PolarHBondContact N-O 3.22Å; V135-I137 HydrophobicContact CG1-CD1 4.49Å; V135-I137 HydrophobicContact CG1-CG1 4.12Å; I137-L304 CarbonylContact C-O 3.58Å; I137-L304 WeakPolarHBondContact CA-O 3.34Å; I137-L304 HydrophobicContact CD1-CD1 4.14Å; I137-L304 HydrophobicContact CG1-CB 4.16Å; I137-L304 HydrophobicContact CG1-CD1 4.06Å; I137-L304 HydrophobicContact CG1-CG 4.34Å; I137-L304 HydrophobicContact CG2-CB 4.3Å; I137-W319 HydrophobicContact CG2-CZ3 3.84Å; I137-L323 HydrophobicContact CD1-CD1 3.73Å
138N98.8Very high97.9Very high0 Ų031.2 Ų31.20%015%0.148CC..EExtended strand (participates in β ladder)trans-128.588.9164.8179.421.7000110.1A15 V117 S121 C140 G141 L304 L305 G306A15-N138 HydrophobicContact CB-CB 4.3Å; V117-N138 PolarHBondContact O-ND2 3.46Å; S121-N138 PolarHBondContact N-ND2 3.43Å; S121-N138 PolarHBondContact OG-ND2 3.43Å; N138-C140 PolarHBondContact O-N 2.62Å; N138-C140 VanDerWaalsContact O-N 3.17Å; N138-C140 WeakPolarHBondContact OD1-CB 3.49Å; N138-C140 PolarHBondContact OD1-N 2.87Å; N138-G141 PolarHBondContact ND2-N 2.91Å; N138-G141 PolarHBondContact O-N 3.23Å; N138-G141 VanDerWaalsContact O-N 3.15Å; N138-G141 PolarHBondContact OD1-N 3.5Å; N138-L304 PolarHBondContact N-O 3.42Å; N138-L305 HydrophobicContact CB-CD2 4.07Å; N138-L305 WeakPolarHBondContact O-CA 3.47Å; N138-G306 PolarHBondContact O-N 3.34Å; N138-G306 VanDerWaalsContact O-N 3.1Å
139L98.4Very high97.8Very high0 Ų033.1 Ų33.10%016%0.161CC..THydrogen-bonded Turntrans-66.9-14.3179.174.788.8000113.6T37 F38 M41 G306 F315 W319T37-L139 HydrophobicContact CG2-CD1 4.35Å; T37-L139 HydrophobicContact CG2-CD2 4.04Å; F38-L139 HydrophobicContact CD1-CD2 3.99Å; F38-L139 HydrophobicContact CE1-CD2 3.42Å; F38-L139 VanDerWaalsContact CE1-CD2 3.42Å; F38-L139 HydrophobicContact CE1-CG 4.06Å; F38-L139 HydrophobicContact CE2-CD1 4.38Å; F38-L139 HydrophobicContact CZ-CD1 4.16Å; F38-L139 HydrophobicContact CZ-CD2 3.74Å; F38-L139 HydrophobicContact CZ-CG 3.85Å; M41-L139 HydrophobicContact CE-CD2 3.81Å; M41-L139 HydrophobicContact SD-CD2 4.04Å; L139-G306 VanDerWaalsContact O-CA 3.28Å; L139-G306 WeakPolarHBondContact O-CA 3.41Å; L139-F315 HydrophobicContact CD1-CE1 4.13Å; L139-F315 HydrophobicContact CD1-CZ 4.47Å; L139-W319 HydrophobicContact CB-CD2 3.78Å; L139-W319 HydrophobicContact CB-CE3 3.56Å; L139-W319 HydrophobicContact CB-CH2 3.9Å; L139-W319 HydrophobicContact CB-CZ2 4.13Å; L139-W319 HydrophobicContact CB-CZ3 3.61Å; L139-W319 HydrophobicContact CD2-CE3 4.4Å
140C98.3Very high97.6Very high2 Ų235.2 Ų35.21%0.01417%0.171CC..THydrogen-bonded Turntrans-86.2-14.8177.3-57.90000113.1L20 T34 V117 N138 W143L20-C140 HydrophobicContact CD1-CB 4.25Å; L20-C140 HydrophobicContact CD2-CB 4.39Å; T34-C140 WeakPolarHBondContact CG2-SG 3.39Å; V117-C140 WeakPolarHBondContact CG1-O 3.32Å; V117-C140 HydrophobicContact CG2-CB 4.11Å; N138-C140 PolarHBondContact O-N 2.62Å; N138-C140 VanDerWaalsContact O-N 3.17Å; N138-C140 WeakPolarHBondContact OD1-CB 3.49Å; N138-C140 PolarHBondContact OD1-N 2.87Å; C140-W143 PolarHBondContact O-NE1 2.91Å
141G98.4Very high97.5Very high0 Ų029.2 Ų29.20%015%0.145CC..  trans-88.4-157.3176.400000112.5N138 D159 G306 G307N138-G141 PolarHBondContact ND2-N 2.91Å; N138-G141 PolarHBondContact O-N 3.23Å; N138-G141 VanDerWaalsContact O-N 3.15Å; N138-G141 PolarHBondContact OD1-N 3.5Å; G141-D159 VanDerWaalsContact CA-OD2 3.25Å; G141-D159 WeakPolarHBondContact CA-OD2 3.45Å; G141-G306 CarbonylContact O-C 3.51Å; G141-G306 WeakPolarHBondContact O-CA 3.49Å; G141-G306 PolarHBondContact O-N 2.93Å; G141-G307 PolarHBondContact O-N 3.24Å
142G98.2Very high97.3Very high1 Ų127 Ų271%0.0112%0.121CC..  trans89.320.718000000114H144 D159 Q267G142-H144 VanDerWaalsContact C-N 3.28Å; G142-H144 PolarHBondContact O-N 2.98Å; G142-D159 PolarHBondContact N-OD1 2.6Å; G142-D159 PolarHBondContact N-OD2 3.44Å; G142-Q267 PolarHBondContact O-NE2 2.87Å
143W97.5Very high97.1Very high16 Ų1623.1 Ų23.16%0.06111%0.105CC..  trans-78.878.4-177.5-61.6108.2000110.6L30 Y113 C140 H145 F154 C155 D159L30-W143 HydrophobicContact CD1-CH2 3.94Å; L30-W143 HydrophobicContact CD1-CZ2 3.92Å; L30-W143 HydrophobicContact CD2-CH2 3.94Å; Y113-W143 WeakPolarHBondContact OH-CZ2 3.47Å; Y113-W143 PolarHBondContact OH-NE1 2.88Å; C140-W143 PolarHBondContact O-NE1 2.91Å; W143-H145 PolarHBondContact O-N 3.37Å; W143-F154 HydrophobicContact CZ3-CB 4.4Å; W143-C155 VanDerWaalsContact CA-SG 3.57Å; W143-C155 HydrophobicContact CB-CB 3.9Å; W143-D159 PolarHBondContact N-OD1 3.33Å
144H97.5Very high96.9Very high4 Ų426 Ų262%0.01912%0.117CC..THydrogen-bonded Turntrans-81.5-7.8-164.667.3172.4000115.6G142 N158 D178 D180 H182 S188 V189G142-H144 VanDerWaalsContact C-N 3.28Å; G142-H144 PolarHBondContact O-N 2.98Å; H144-N158 PolarHBondContact O-ND2 2.96Å; H144-D178 IonicContact CE1-OD1 3.14Å; H144-D178 IonicContact CE1-OD2 3.43Å; H144-D178 IonicContact CG-OD2 3.1Å; H144-D178 IonicContact ND1-OD1 3.12Å; H144-D178 IonicContact ND1-OD2 2.89Å; H144-D178 PolarHBondContact ND1-OD2 2.57Å; H144-D180 VanDerWaalsContact CE1-CB 3.47Å; H144-D180 WeakPolarHBondContact CE1-CB 3.34Å; H144-D180 IonicContact CE1-OD1 2.91Å; H144-D180 IonicContact NE2-OD1 3.02Å; H144-H182 PolarHBondContact CE1-O 3.47Å; H144-S188 WeakPolarHBondContact O-CB 3.47Å; H144-S188 PolarHBondContact O-OG 3.22Å; H144-V189 HydrophobicContact CB-CG2 3.85Å; H144-V189 WeakPolarHBondContact O-CG2 3.24Å
145H97.3Very high96.8Very high7 Ų721.1 Ų21.13%0.03210%0.096CC..THydrogen-bonded Turntrans-92.2-13.3-177.3-69.1-60.3000114.4W143 R147 A152 C155 H182 H183 D185 S188 Y212W143-H145 PolarHBondContact O-N 3.37Å; H145-R147 PolarHBondContact O-N 3.47Å; H145-A152 HydrophobicContact CB-CB 4.29Å; H145-A152 VanDerWaalsContact CB-O 3.23Å; H145-A152 WeakPolarHBondContact CB-O 3.22Å; H145-C155 HydrophobicContact CB-CB 4.01Å; H145-C155 PolarHBondContact N-SG 2.92Å; H145-C155 VanDerWaalsContact N-SG 3.37Å; H145-H182 WeakPolarHBondContact NE2-CB 3.44Å; H145-H183 PolarHBondContact CE1-O 3.2Å; H145-D185 IonicContact CE1-OD2 3.95Å; H145-D185 IonicContact CG-OD2 3.85Å; H145-D185 IonicContact ND1-OD2 3.62Å; H145-D185 PolarHBondContact ND1-OD2 2.89Å; H145-S188 WeakPolarHBondContact O-CB 3.21Å; H145-Y212 AromaticContact CD2-CE1 3.82Å; H145-Y212 AromaticContact CE1-CE1 3.63Å; H145-Y212 AromaticContact CG-CE1 3.89Å; H145-Y212 AromaticContact ND1-CE1 3.75Å; H145-Y212 AromaticContact NE2-CD1 3.94Å; H145-Y212 AromaticContact NE2-CE1 3.62Å
146A96.4Very high96.8Very high0 Ų021.7 Ų21.70%010%0.098CC..  trans-62.7132.2-177.400000110.4C155 F157 N158A146-C155 HydrophobicContact CB-CB 3.71Å; A146-F157 VanDerWaalsContact CB-C 3.47Å; A146-N158 HydrophobicContact CB-CB 3.85Å; A146-N158 WeakPolarHBondContact O-CB 3.42Å; A146-N158 PolarHBondContact O-ND2 3.39Å
147R95.6Very high96.7Very high83 Ų8322 Ų2231%0.31310%0.099SC..BIsolated β-bridgetrans-98175.5179.8-45.3-169.6174.8169.7-13.6110.4H67 H145 S149 Q150 A187H67-R147 PolarHBondContact CE1-O 3.41Å; H67-R147 PolarHBondContact ND1-O 3.06Å; H145-R147 PolarHBondContact O-N 3.47Å; R147-S149 VanDerWaalsContact C-N 3.26Å; R147-S149 PolarHBondContact O-N 3.4Å; R147-Q150 HydrophobicContact CB-CB 3.98Å; R147-Q150 HydrophobicContact CG-CB 4.23Å; R147-Q150 PolarHBondContact N-O 3.08Å; R147-A187 VanDerWaalsContact CG-O 3.23Å; R147-A187 WeakPolarHBondContact CG-O 3.47Å
148R95Very high96.7Very high141 Ų14121.8 Ų21.853%0.53210%0.098SC..THydrogen-bonded Turntrans-54.8-41.6178175.5161.4-165.5-80.5-1.2113.1F66 H67 S68F66-R148 HydrophobicContact CE2-CB 4.2Å; F66-R148 HydrophobicContact CZ-CB 4.16Å; F66-R148 VanDerWaalsContact O-CG 3.31Å; F66-R148 WeakPolarHBondContact O-CG 3.43Å; F66-R148 PolarHBondContact O-NE 2.93Å; H67-R148 CarbonylContact C-O 3.5Å; H67-R148 WeakPolarHBondContact CA-O 3.41Å; H67-R148 PolarHBondContact ND1-O 3.31Å; S68-R148 PolarHBondContact N-O 3.33Å
149S95.2Very high96.6Very high40 Ų4021.8 Ų21.828%0.2810%0.098SC..THydrogen-bonded Turntrans-13426.4-174.5-56.20000111.8S68 F98 R147S68-S149 VanDerWaalsContact CB-OG 3.22Å; S68-S149 WeakPolarHBondContact CB-OG 3.27Å; S68-S149 WeakPolarHBondContact OG-CB 3.22Å; S68-S149 PolarHBondContact OG-OG 3.42Å; F98-S149 WeakPolarHBondContact CD1-O 3.44Å; R147-S149 VanDerWaalsContact C-N 3.26Å; R147-S149 PolarHBondContact O-N 3.4Å
150Q95.4Very high96.6Very high57 Ų5721.8 Ų21.827%0.26610%0.098SC..BIsolated β-bridgetrans-154.3132.8-174.4-157.7176.137.700111.1G97 F98 R147G97-Q150 PolarHBondContact O-NE2 3.27Å; F98-Q150 CarbonylContact O-C 3.45Å; F98-Q150 WeakPolarHBondContact O-CA 3.44Å; R147-Q150 HydrophobicContact CB-CB 3.98Å; R147-Q150 HydrophobicContact CG-CB 4.23Å; R147-Q150 PolarHBondContact N-O 3.08Å
151A95.8Very high96.6Very high2 Ų221.7 Ų21.72%0.01710%0.098CC..  trans-75.7147.6163.900000109.4Y71 F98 V100 C104 C155 Y156Y71-A151 VanDerWaalsContact OH-CA 3.29Å; Y71-A151 WeakPolarHBondContact OH-CA 3.24Å; Y71-A151 VanDerWaalsContact OH-CB 3.28Å; Y71-A151 WeakPolarHBondContact OH-CB 3.4Å; Y71-A151 PolarHBondContact OH-N 2.9Å; F98-A151 PolarHBondContact O-N 3.29Å; V100-A151 HydrophobicContact CG1-CB 4.13Å; C104-A151 HydrophobicContact CB-CB 3.79Å; A151-C155 VanDerWaalsContact CA-O 3.25Å; A151-C155 WeakPolarHBondContact CA-O 3.3Å; A151-Y156 HydrophobicContact CB-CD1 3.87Å; A151-Y156 HydrophobicContact CB-CE1 4.35Å; A151-Y156 HydrophobicContact CB-CG 4.48Å
152A95.2Very high96.6Very high6 Ų622 Ų225%0.0510%0.099CC..BIsolated β-bridgetrans-160.6143176.700000110.4H145 F154 C155 Y212H145-A152 HydrophobicContact CB-CB 4.29Å; H145-A152 VanDerWaalsContact CB-O 3.23Å; H145-A152 WeakPolarHBondContact CB-O 3.22Å; A152-F154 PolarHBondContact O-N 2.95Å; A152-C155 PolarHBondContact N-O 3.28Å; A152-C155 WeakPolarHBondContact O-CA 3.02Å; A152-C155 WeakPolarHBondContact O-CB 3.43Å; A152-C155 PolarHBondContact O-N 3.06Å; A152-Y212 WeakPolarHBondContact CB-OH 3.35Å
153G93.3Very high96.7Very high7 Ų722 Ų227%0.07210%0.099CC..THydrogen-bonded Turntrans55.848.4170.300000113.1D103 C155D103-G153 WeakPolarHBondContact OD2-CA 3.32Å; D103-G153 PolarHBondContact OD2-N 2.79Å; G153-C155 PolarHBondContact O-N 2.84Å; G153-C155 VanDerWaalsContact O-N 3.12Å; G153-C155 PolarHBondContact O-SG 3.21Å
154F94.3Very high96.7Very high69 Ų6921.2 Ų21.230%0.30310%0.096SC..THydrogen-bonded Turntrans66.31.6-174.5-40.2-68.1000115.7T29 D103 C104 W143 A152 Y156 Y310T29-F154 HydrophobicContact CG2-CD1 4.49Å; T29-F154 HydrophobicContact CG2-CE1 4.38Å; D103-F154 HydrophobicContact CB-CE1 4.25Å; D103-F154 WeakPolarHBondContact O-CD1 3.49Å; D103-F154 WeakPolarHBondContact O-CE1 3.39Å; C104-F154 PolarHBondContact SG-N 2.96Å; C104-F154 VanDerWaalsContact SG-N 3.37Å; W143-F154 HydrophobicContact CZ3-CB 4.4Å; A152-F154 PolarHBondContact O-N 2.95Å; F154-Y156 WeakPolarHBondContact O-CE2 3.42Å; F154-Y310 HydrophobicContact CD2-CE1 4.16Å; F154-Y310 HydrophobicContact CE2-CE1 4.11Å
155C96.7Very high96.7Very high2 Ų223.2 Ų23.21%0.01411%0.107CC..BIsolated β-bridgetrans-102121.4-175.1-54.30000111W143 H145 A146 A151 A152 G153W143-C155 VanDerWaalsContact CA-SG 3.57Å; W143-C155 HydrophobicContact CB-CB 3.9Å; H145-C155 HydrophobicContact CB-CB 4.01Å; H145-C155 PolarHBondContact N-SG 2.92Å; H145-C155 VanDerWaalsContact N-SG 3.37Å; A146-C155 HydrophobicContact CB-CB 3.71Å; A151-C155 VanDerWaalsContact CA-O 3.25Å; A151-C155 WeakPolarHBondContact CA-O 3.3Å; A152-C155 PolarHBondContact N-O 3.28Å; A152-C155 WeakPolarHBondContact O-CA 3.02Å; A152-C155 WeakPolarHBondContact O-CB 3.43Å; A152-C155 PolarHBondContact O-N 3.06Å; G153-C155 PolarHBondContact O-N 2.84Å; G153-C155 VanDerWaalsContact O-N 3.12Å; G153-C155 PolarHBondContact O-SG 3.21Å
156Y96.7Very high96.8Very high15 Ų1524.8 Ų24.86%0.05911%0.113CC..SBendtrans-104.9-35.4178.4-56.1-94.5000112.8Y71 L75 C104 P105 F107 L110 A151 F154Y71-Y156 VanDerWaalsContact CE1-O 3.32Å; Y71-Y156 WeakPolarHBondContact CE1-O 3.42Å; Y71-Y156 PolarHBondContact OH-O 3.41Å; L75-Y156 HydrophobicContact CD2-CD1 4.2Å; C104-Y156 WeakPolarHBondContact CA-OH 3.27Å; C104-Y156 HydrophobicContact CB-CE1 3.76Å; C104-Y156 PolarHBondContact O-OH 2.79Å; P105-Y156 PolarHBondContact O-OH 3.23Å; F107-Y156 HydrophobicContact CE1-CE2 4.36Å; L110-Y156 HydrophobicContact CD1-CD1 3.76Å; L110-Y156 HydrophobicContact CD1-CD2 3.45Å; L110-Y156 VanDerWaalsContact CD1-CD2 3.45Å; L110-Y156 HydrophobicContact CD1-CE1 3.79Å; L110-Y156 HydrophobicContact CD1-CE2 3.49Å; L110-Y156 VanDerWaalsContact CD1-CE2 3.49Å; L110-Y156 HydrophobicContact CD1-CG 3.59Å; L110-Y156 HydrophobicContact CD2-CD1 3.75Å; L110-Y156 HydrophobicContact CD2-CE1 3.73Å; L110-Y156 HydrophobicContact CD2-CG 4.35Å; L110-Y156 HydrophobicContact CG-CD1 4.31Å; L110-Y156 HydrophobicContact CG-CE1 4.42Å; L110-Y156 HydrophobicContact CG-CG 4.44Å; A151-Y156 HydrophobicContact CB-CD1 3.87Å; A151-Y156 HydrophobicContact CB-CE1 4.35Å; A151-Y156 HydrophobicContact CB-CG 4.48Å; F154-Y156 WeakPolarHBondContact O-CE2 3.42Å
157F97.7Very high96.9Very high5 Ų524.8 Ų24.82%0.02211%0.113CC..SBendtrans-125.1137.3173.4-64.6-66.8000109L63 H67 V72 L75 Y111 T115 T118 A146 D159L63-F157 HydrophobicContact CD1-CE1 3.94Å; L63-F157 HydrophobicContact CD1-CZ 4.04Å; L63-F157 HydrophobicContact CD2-CD1 3.79Å; L63-F157 HydrophobicContact CD2-CE1 4.05Å; L63-F157 HydrophobicContact CD2-CG 4.1Å; L63-F157 HydrophobicContact CG-CE1 4.42Å; H67-F157 AromaticContact CD2-CD1 3.79Å; H67-F157 WeakPolarHBondContact NE2-CA 3.35Å; H67-F157 AromaticContact NE2-CD1 3.86Å; V72-F157 HydrophobicContact CG2-CE1 4.38Å; L75-F157 HydrophobicContact CB-CZ 4.14Å; L75-F157 HydrophobicContact CD1-CD1 4.32Å; L75-F157 HydrophobicContact CD1-CE1 3.66Å; L75-F157 HydrophobicContact CD1-CE2 3.98Å; L75-F157 HydrophobicContact CD1-CZ 3.47Å; L75-F157 VanDerWaalsContact CD1-CZ 3.47Å; L75-F157 HydrophobicContact CG-CZ 4.49Å; Y111-F157 HydrophobicContact CD2-CE2 4.34Å; Y111-F157 HydrophobicContact CD2-CZ 4.03Å; Y111-F157 AromaticContact CE2-CZ 3.94Å; Y111-F157 HydrophobicContact CE2-CZ 3.94Å; T115-F157 HydrophobicContact CG2-CE2 4.29Å; T118-F157 WeakPolarHBondContact OG1-CB 3.46Å; A146-F157 VanDerWaalsContact CB-C 3.47Å; F157-D159 PolarHBondContact O-N 2.78Å
158N98Very high97.1Very high0 Ų024.5 Ų24.50%011%0.112CC..  trans-91.283.7-179.9-159.2-46.7000109.8F66 H67 H144 A146 C160 V161 L162F66-N158 HydrophobicContact CD1-CB 4.09Å; F66-N158 HydrophobicContact CE1-CB 3.73Å; H67-N158 PolarHBondContact CE1-N 2.89Å; H67-N158 PolarHBondContact NE2-N 2.93Å; H144-N158 PolarHBondContact O-ND2 2.96Å; A146-N158 HydrophobicContact CB-CB 3.85Å; A146-N158 WeakPolarHBondContact O-CB 3.42Å; A146-N158 PolarHBondContact O-ND2 3.39Å; N158-C160 PolarHBondContact O-N 3.34Å; N158-C160 WeakPolarHBondContact OD1-CB 3.4Å; N158-C160 PolarHBondContact OD1-N 2.94Å; N158-V161 HydrophobicContact CB-CB 4.17Å; N158-V161 HydrophobicContact CB-CG2 4.2Å; N158-V161 PolarHBondContact O-N 2.82Å; N158-V161 WeakPolarHBondContact OD1-CG2 3.39Å; N158-V161 PolarHBondContact OD1-N 3.11Å; N158-L162 PolarHBondContact O-N 3.26Å; N158-L162 VanDerWaalsContact O-N 3.13Å
159D98.6Very high97.2Very high0 Ų023.5 Ų23.50%011%0.114CC..Hα-helixtrans-68.5-22.9-179.773.7-73.8000112.5T118 S121 G141 G142 W143 F157 S163T118-D159 HydrophobicContact CG2-CB 4.17Å; S121-D159 WeakPolarHBondContact CB-OD2 3.38Å; S121-D159 PolarHBondContact OG-OD2 3.41Å; G141-D159 VanDerWaalsContact CA-OD2 3.25Å; G141-D159 WeakPolarHBondContact CA-OD2 3.45Å; G142-D159 PolarHBondContact N-OD1 2.6Å; G142-D159 PolarHBondContact N-OD2 3.44Å; W143-D159 PolarHBondContact N-OD1 3.33Å; F157-D159 PolarHBondContact O-N 2.78Å; D159-S163 WeakPolarHBondContact O-CB 3.29Å; D159-S163 PolarHBondContact O-N 3.27Å; D159-S163 PolarHBondContact O-OG 3.11Å
160C98.4Very high97.4Very high0 Ų029.1 Ų29.10%013%0.129CC..Hα-helixtrans-61.9-52.9169.5-57.30000110.9N158 L162 S163 I164 Y176 V189 L305N158-C160 PolarHBondContact O-N 3.34Å; N158-C160 WeakPolarHBondContact OD1-CB 3.4Å; N158-C160 PolarHBondContact OD1-N 2.94Å; C160-L162 PolarHBondContact O-N 2.93Å; C160-S163 PolarHBondContact O-N 3.15Å; C160-S163 PolarHBondContact O-OG 3.38Å; C160-I164 WeakPolarHBondContact O-CD1 3.43Å; C160-I164 VanDerWaalsContact O-CG1 3.25Å; C160-I164 WeakPolarHBondContact O-CG1 3.32Å; C160-I164 PolarHBondContact O-N 3.37Å; C160-Y176 HydrophobicContact CB-CE2 4Å; C160-V189 HydrophobicContact CB-CG2 3.78Å; C160-L305 HydrophobicContact CB-CD1 4.31Å
161V98.2Very high97.5Very high1 Ų127.8 Ų27.81%0.00612%0.121CC..Hα-helixtrans-62.6-47180171.80000111.1F66 N158 S163 I164 L165 V189 A192 F193F66-V161 HydrophobicContact CB-CG1 4.01Å; F66-V161 HydrophobicContact CD1-CB 4.25Å; F66-V161 HydrophobicContact CD1-CG1 4.01Å; F66-V161 HydrophobicContact CD2-CG1 3.58Å; F66-V161 HydrophobicContact CE1-CB 4.41Å; F66-V161 HydrophobicContact CE1-CG1 4.37Å; F66-V161 HydrophobicContact CE1-CG2 4.46Å; F66-V161 HydrophobicContact CE2-CG1 3.97Å; F66-V161 HydrophobicContact CG-CB 4.33Å; F66-V161 HydrophobicContact CG-CG1 3.59Å; F66-V161 HydrophobicContact CZ-CG1 4.35Å; F66-V161 HydrophobicContact CZ-CG2 4.37Å; N158-V161 HydrophobicContact CB-CB 4.17Å; N158-V161 HydrophobicContact CB-CG2 4.2Å; N158-V161 PolarHBondContact O-N 2.82Å; N158-V161 WeakPolarHBondContact OD1-CG2 3.39Å; N158-V161 PolarHBondContact OD1-N 3.11Å; V161-S163 VanDerWaalsContact C-N 3.34Å; V161-S163 PolarHBondContact O-N 3.32Å; V161-I164 PolarHBondContact O-N 3.44Å; V161-L165 HydrophobicContact CG1-CD1 3.85Å; V161-L165 HydrophobicContact CG1-CG 4.28Å; V161-L165 VanDerWaalsContact O-CG 3.32Å; V161-L165 WeakPolarHBondContact O-CG 3.38Å; V161-L165 PolarHBondContact O-N 3.17Å; V161-V189 HydrophobicContact CG2-CB 4.39Å; V161-V189 HydrophobicContact CG2-CG1 4.38Å; V161-V189 HydrophobicContact CG2-CG2 4.2Å; V161-A192 HydrophobicContact CB-CB 4.49Å; V161-A192 HydrophobicContact CG1-CB 3.94Å; V161-A192 HydrophobicContact CG2-CB 3.63Å; V161-F193 HydrophobicContact CB-CE2 4.46Å; V161-F193 HydrophobicContact CG1-CE2 4.28Å; V161-F193 HydrophobicContact CG1-CZ 4.02Å; V161-F193 HydrophobicContact CG2-CE2 4.11Å
162L98.5Very high97.6Very high6 Ų634.4 Ų34.43%0.03115%0.15CC..Hα-helixtrans-63.9-38.7-179.1-71.2169.9000112.3E62 L63 F66 T118 I122 N158 C160 L165 K166E62-L162 VanDerWaalsContact O-CD2 3.26Å; E62-L162 WeakPolarHBondContact O-CD2 3.28Å; L63-L162 HydrophobicContact CD2-CD1 4.12Å; F66-L162 HydrophobicContact CB-CD2 3.72Å; F66-L162 HydrophobicContact CB-CG 4.26Å; T118-L162 HydrophobicContact CG2-CD1 3.41Å; T118-L162 VanDerWaalsContact CG2-CD1 3.41Å; I122-L162 HydrophobicContact CD1-CB 4.19Å; I122-L162 HydrophobicContact CD1-CD1 4.49Å; I122-L162 HydrophobicContact CG1-CB 4.13Å; N158-L162 PolarHBondContact O-N 3.26Å; N158-L162 VanDerWaalsContact O-N 3.13Å; C160-L162 PolarHBondContact O-N 2.93Å; L162-L165 PolarHBondContact O-N 3.18Å; L162-K166 WeakPolarHBondContact O-CB 3.38Å; L162-K166 PolarHBondContact O-N 2.83Å
163S98.7Very high97.7Very high0 Ų036 Ų360%016%0.155CC..Hα-helixtrans-68.5-37.1174.760.90000112.8D159 C160 V161 K166 L167 L303D159-S163 WeakPolarHBondContact O-CB 3.29Å; D159-S163 PolarHBondContact O-N 3.27Å; D159-S163 PolarHBondContact O-OG 3.11Å; C160-S163 PolarHBondContact O-N 3.15Å; C160-S163 PolarHBondContact O-OG 3.38Å; V161-S163 VanDerWaalsContact C-N 3.34Å; V161-S163 PolarHBondContact O-N 3.32Å; S163-K166 WeakPolarHBondContact O-CB 3.49Å; S163-K166 PolarHBondContact O-N 3.06Å; S163-L167 WeakPolarHBondContact O-CG 3.32Å; S163-L167 PolarHBondContact O-N 2.77Å; S163-L303 VanDerWaalsContact CB-CD2 3.44Å; S163-L303 WeakPolarHBondContact OG-CD2 3.4Å
164I98.6Very high98Very high0 Ų035.7 Ų35.70%015%0.151CC..Hα-helixtrans-62.9-46.9172.3-68.4163.4000110.5C160 V161 K166 L167 R168 I174 Y176 V189 F193 V199 V265C160-I164 WeakPolarHBondContact O-CD1 3.43Å; C160-I164 VanDerWaalsContact O-CG1 3.25Å; C160-I164 WeakPolarHBondContact O-CG1 3.32Å; C160-I164 PolarHBondContact O-N 3.37Å; V161-I164 PolarHBondContact O-N 3.44Å; I164-K166 VanDerWaalsContact C-N 3.27Å; I164-K166 PolarHBondContact O-N 2.92Å; I164-L167 PolarHBondContact O-N 3.45Å; I164-R168 HydrophobicContact CG2-CG 4.33Å; I164-R168 VanDerWaalsContact O-CG 3.28Å; I164-R168 WeakPolarHBondContact O-CG 3.23Å; I164-R168 PolarHBondContact O-N 3.02Å; I164-I174 HydrophobicContact CG1-CG2 4.23Å; I164-I174 HydrophobicContact CG2-CB 4.26Å; I164-I174 HydrophobicContact CG2-CG1 4.29Å; I164-I174 HydrophobicContact CG2-CG2 4.18Å; I164-Y176 HydrophobicContact CD1-CD2 3.87Å; I164-Y176 HydrophobicContact CD1-CG 4.08Å; I164-V189 HydrophobicContact CD1-CG1 4.13Å; I164-F193 HydrophobicContact CB-CE2 4.03Å; I164-F193 HydrophobicContact CB-CZ 3.8Å; I164-F193 HydrophobicContact CD1-CD2 4.36Å; I164-F193 HydrophobicContact CD1-CE2 3.65Å; I164-F193 HydrophobicContact CD1-CZ 4.32Å; I164-F193 HydrophobicContact CG1-CE2 4.46Å; I164-F193 HydrophobicContact CG2-CE1 3.94Å; I164-F193 HydrophobicContact CG2-CE2 3.77Å; I164-F193 HydrophobicContact CG2-CZ 3.38Å; I164-V199 HydrophobicContact CG2-CG1 4.06Å; I164-V199 HydrophobicContact CG2-CG2 3.79Å; I164-V265 HydrophobicContact CG1-CB 4.39Å; I164-V265 HydrophobicContact CG1-CG2 3.86Å
165L98.2Very high98.2Very high46 Ų4632.4 Ų32.424%0.24114%0.137CC..Hα-helixtrans-58.7-40.9176.3-69.9170.8000111.1Y65 F66 V161 L162 R168 F193Y65-L165 HydrophobicContact CD1-CB 4.35Å; Y65-L165 HydrophobicContact CD1-CD1 4.2Å; F66-L165 HydrophobicContact CB-CD1 4.1Å; V161-L165 HydrophobicContact CG1-CD1 3.85Å; V161-L165 HydrophobicContact CG1-CG 4.28Å; V161-L165 VanDerWaalsContact O-CG 3.32Å; V161-L165 WeakPolarHBondContact O-CG 3.38Å; V161-L165 PolarHBondContact O-N 3.17Å; L162-L165 PolarHBondContact O-N 3.18Å; L165-R168 WeakPolarHBondContact O-CB 3.45Å; L165-R168 PolarHBondContact O-N 2.93Å; L165-F193 HydrophobicContact CD2-CE1 4.14Å; L165-F193 HydrophobicContact CD2-CZ 4.43Å; L165-F193 HydrophobicContact CG-CZ 4.39Å
166K98.7Very high98.3Very high41 Ų4132.4 Ų32.418%0.17814%0.137CC..Hα-helixtrans-61.4-50173.6-172.955.9171.4171.10111.5I122 A125 D126 N129 L162 S163 I164 R168 E169I122-K166 HydrophobicContact CG2-CD 4.43Å; I122-K166 HydrophobicContact CG2-CG 4.19Å; A125-K166 HydrophobicContact CB-CB 3.83Å; A125-K166 HydrophobicContact CB-CG 3.79Å; D126-K166 HydrophobicContact CB-CG 4.47Å; D126-K166 VanDerWaalsContact OD1-CE 3.22Å; D126-K166 WeakPolarHBondContact OD1-CE 3.35Å; D126-K166 IonicContact OD1-NZ 2.77Å; N129-K166 PolarHBondContact ND2-O 3.45Å; L162-K166 WeakPolarHBondContact O-CB 3.38Å; L162-K166 PolarHBondContact O-N 2.83Å; S163-K166 WeakPolarHBondContact O-CB 3.49Å; S163-K166 PolarHBondContact O-N 3.06Å; I164-K166 VanDerWaalsContact C-N 3.27Å; I164-K166 PolarHBondContact O-N 2.92Å; K166-R168 PolarHBondContact O-N 2.86Å; K166-E169 WeakPolarHBondContact CD-OE1 3.39Å; K166-E169 VanDerWaalsContact NZ-CD 3.32Å; K166-E169 IonicContact NZ-OE1 2.95Å; K166-E169 PolarHBondContact NZ-OE1 2.71Å; K166-E169 VanDerWaalsContact NZ-OE1 3.09Å; K166-E169 IonicContact NZ-OE2 3.98Å; K166-E169 PolarHBondContact NZ-OE2 3.2Å; K166-E169 VanDerWaalsContact O-CB 3.3Å; K166-E169 WeakPolarHBondContact O-CB 3.42Å; K166-E169 WeakPolarHBondContact O-CG 3.31Å; K166-E169 PolarHBondContact O-N 3.36Å; K166-E169 VanDerWaalsContact O-N 3.16Å
167L98.8Very high98.3Very high0 Ų031.8 Ų31.80%014%0.135CC..Hα-helixtrans-59.4-33.8177.2-72.2172.1000112.7A125 L128 N129 S163 I164 E169 R170 Y171 I174 A263 V265A125-L167 HydrophobicContact CB-CD2 4.05Å; A125-L167 HydrophobicContact CB-CG 3.84Å; L128-L167 HydrophobicContact CB-CD2 3.88Å; L128-L167 HydrophobicContact CD1-CD2 4.07Å; N129-L167 WeakPolarHBondContact OD1-CA 3.24Å; N129-L167 PolarHBondContact OD1-O 2.96Å; S163-L167 WeakPolarHBondContact O-CG 3.32Å; S163-L167 PolarHBondContact O-N 2.77Å; I164-L167 PolarHBondContact O-N 3.45Å; L167-E169 PolarHBondContact O-N 3.17Å; L167-R170 PolarHBondContact O-N 3.05Å; L167-Y171 HydrophobicContact CB-CD2 4.31Å; L167-Y171 HydrophobicContact CD2-CD2 3.93Å; L167-Y171 HydrophobicContact CD2-CE2 4.01Å; L167-Y171 PolarHBondContact O-N 3.27Å; L167-I174 HydrophobicContact CB-CD1 3.64Å; L167-I174 HydrophobicContact CB-CG1 4.37Å; L167-I174 HydrophobicContact CD1-CD1 4.42Å; L167-I174 HydrophobicContact CD1-CG2 4.48Å; L167-A263 HydrophobicContact CD1-CB 4.48Å; L167-V265 HydrophobicContact CD1-CG2 3.42Å; L167-V265 VanDerWaalsContact CD1-CG2 3.42Å
168R98.2Very high98.3Very high76 Ų7631.6 Ų31.629%0.28713%0.134SC..Hα-helixtrans-64.5-16.6179.3-75.4-69.6-63.499.92.6114I164 L165 K166 R170 Y171 K172 I174 V199I164-R168 HydrophobicContact CG2-CG 4.33Å; I164-R168 VanDerWaalsContact O-CG 3.28Å; I164-R168 WeakPolarHBondContact O-CG 3.23Å; I164-R168 PolarHBondContact O-N 3.02Å; L165-R168 WeakPolarHBondContact O-CB 3.45Å; L165-R168 PolarHBondContact O-N 2.93Å; K166-R168 PolarHBondContact O-N 2.86Å; R168-R170 PolarHBondContact O-N 3.43Å; R168-Y171 PolarHBondContact NH1-O 3.36Å; R168-K172 VanDerWaalsContact CZ-O 3.25Å; R168-K172 PolarHBondContact NE-O 3.23Å; R168-K172 VanDerWaalsContact NH1-CA 3.29Å; R168-K172 PolarHBondContact NH1-O 2.84Å; R168-I174 HydrophobicContact CG-CG1 3.89Å; R168-V199 HydrophobicContact CG-CG2 4.37Å
169E98.4Very high98.4Very high121 Ų12131.7 Ų31.757%0.56513%0.134SC*.THydrogen-bonded Turntrans-60.6-29.8170.3-65.3177.1-176.100112.2K166 L167K166-E169 WeakPolarHBondContact CD-OE1 3.39Å; K166-E169 VanDerWaalsContact NZ-CD 3.32Å; K166-E169 IonicContact NZ-OE1 2.95Å; K166-E169 PolarHBondContact NZ-OE1 2.71Å; K166-E169 VanDerWaalsContact NZ-OE1 3.09Å; K166-E169 IonicContact NZ-OE2 3.98Å; K166-E169 PolarHBondContact NZ-OE2 3.2Å; K166-E169 VanDerWaalsContact O-CB 3.3Å; K166-E169 WeakPolarHBondContact O-CB 3.42Å; K166-E169 WeakPolarHBondContact O-CG 3.31Å; K166-E169 PolarHBondContact O-N 3.36Å; K166-E169 VanDerWaalsContact O-N 3.16Å; L167-E169 PolarHBondContact O-N 3.17Å
170R98.5Very high98.3Very high157 Ų15731.8 Ų31.859%0.59214%0.135SC*.THydrogen-bonded Turntrans-115.1-45.1179179.1175179.885.4-1.4113.3N129 L167 R168N129-R170 HydrophobicContact CB-CB 4.37Å; N129-R170 WeakPolarHBondContact O-CD 3.2Å; N129-R170 PolarHBondContact O-NE 3.13Å; N129-R170 WeakPolarHBondContact OD1-CB 3.19Å; L167-R170 PolarHBondContact O-N 3.05Å; R168-R170 PolarHBondContact O-N 3.43Å
171Y98.5Very high98.3Very high29 Ų2931.8 Ų31.811%0.11414%0.135CC..  trans-98.4118.7-169.2-61.6-67.6000110.4L128 N129 L167 R168 R173 I174 H262 A263 P301L128-Y171 PolarHBondContact O-OH 2.78Å; N129-Y171 WeakPolarHBondContact OD1-CD2 3.33Å; N129-Y171 WeakPolarHBondContact OD1-CE2 3.32Å; L167-Y171 HydrophobicContact CB-CD2 4.31Å; L167-Y171 HydrophobicContact CD2-CD2 3.93Å; L167-Y171 HydrophobicContact CD2-CE2 4.01Å; L167-Y171 PolarHBondContact O-N 3.27Å; R168-Y171 PolarHBondContact NH1-O 3.36Å; Y171-R173 PolarHBondContact O-N 3.35Å; Y171-I174 HydrophobicContact CG-CD1 4.5Å; Y171-H262 HydrophobicContact CD1-CB 3.91Å; Y171-H262 HydrophobicContact CG-CB 4.37Å; Y171-A263 HydrophobicContact CD1-CB 4.27Å; Y171-A263 HydrophobicContact CD2-CB 3.71Å; Y171-A263 HydrophobicContact CE2-CB 4.19Å; Y171-A263 HydrophobicContact CG-CB 3.76Å; Y171-P301 HydrophobicContact CE1-CG 3.87Å; Y171-P301 HydrophobicContact CE2-CB 4.3Å; Y171-P301 HydrophobicContact CE2-CG 4.42Å; Y171-P301 WeakPolarHBondContact OH-CG 3.35Å
172K97.8Very high98.3Very high142 Ų14232.5 Ų32.562%0.61714%0.138SC*.SBendtrans-62.8-39-177.8-64.8-176.6177.8177.90114.4R168 N198 H262R168-K172 VanDerWaalsContact CZ-O 3.25Å; R168-K172 PolarHBondContact NE-O 3.23Å; R168-K172 VanDerWaalsContact NH1-CA 3.29Å; R168-K172 PolarHBondContact NH1-O 2.84Å; K172-N198 WeakPolarHBondContact O-CB 3.41Å; K172-H262 PolarHBondContact N-ND1 3.09Å
173R97.8Very high98.2Very high39 Ų3932.2 Ų32.215%0.14714%0.137CC..  trans-124.1122.6-177.1-70-173.3-59.4-93.3-1.1110.8Y171 N198 F259 D260 H262 A263Y171-R173 PolarHBondContact O-N 3.35Å; R173-N198 VanDerWaalsContact CA-O 3.27Å; R173-N198 WeakPolarHBondContact CA-O 3.18Å; R173-F259 HydrophobicContact CB-CE1 3.95Å; R173-F259 HydrophobicContact CB-CE2 4.35Å; R173-F259 HydrophobicContact CB-CZ 3.75Å; R173-F259 WeakPolarHBondContact CD-O 3.42Å; R173-F259 HydrophobicContact CG-CE2 4.32Å; R173-F259 HydrophobicContact CG-CZ 4.18Å; R173-F259 PolarHBondContact NE-O 3.21Å; R173-D260 VanDerWaalsContact CZ-O 3.26Å; R173-D260 IonicContact CZ-OD2 3.92Å; R173-D260 PolarHBondContact NE-O 2.67Å; R173-D260 PolarHBondContact NH2-O 2.96Å; R173-D260 IonicContact NH2-OD2 3.63Å; R173-D260 PolarHBondContact NH2-OD2 3.27Å; R173-H262 PolarHBondContact NH2-NE2 2.85Å; R173-H262 PolarHBondContact O-N 3.05Å; R173-A263 PolarHBondContact O-N 2.86Å
174I98.5Very high97.6Very high0 Ų032.4 Ų32.40%014%0.138CC..EExtended strand (participates in β ladder)trans-114.1127.2179.4-50-62.3000109I164 L167 R168 Y171 N198 V199 M200 F259 A263 V265I164-I174 HydrophobicContact CG1-CG2 4.23Å; I164-I174 HydrophobicContact CG2-CB 4.26Å; I164-I174 HydrophobicContact CG2-CG1 4.29Å; I164-I174 HydrophobicContact CG2-CG2 4.18Å; L167-I174 HydrophobicContact CB-CD1 3.64Å; L167-I174 HydrophobicContact CB-CG1 4.37Å; L167-I174 HydrophobicContact CD1-CD1 4.42Å; L167-I174 HydrophobicContact CD1-CG2 4.48Å; R168-I174 HydrophobicContact CG-CG1 3.89Å; Y171-I174 HydrophobicContact CG-CD1 4.5Å; I174-N198 PolarHBondContact N-O 2.91Å; I174-V199 HydrophobicContact CB-CG2 4.33Å; I174-V199 WeakPolarHBondContact O-CA 3.46Å; I174-M200 PolarHBondContact O-N 3.42Å; I174-F259 VanDerWaalsContact O-CE1 3.23Å; I174-F259 WeakPolarHBondContact O-CE1 3.49Å; I174-F259 WeakPolarHBondContact O-CZ 3.38Å; I174-A263 WeakPolarHBondContact CA-O 3.34Å; I174-A263 HydrophobicContact CD1-CB 3.88Å; I174-V265 HydrophobicContact CG2-CG2 4.09Å
175L98.3Very high96.6Very high1 Ų132.5 Ų32.51%0.00514%0.139CC..EExtended strand (participates in β ladder)trans-94.2120.8169.3179.165.2000108.4V177 M200 V202 F259 P261 A263 I264 V265L175-V177 HydrophobicContact CD1-CG2 4.47Å; L175-V177 HydrophobicContact CD2-CG2 3.91Å; L175-V177 HydrophobicContact CG-CG2 3.82Å; L175-M200 HydrophobicContact CD1-CB 4.08Å; L175-M200 HydrophobicContact CD1-CG 3.96Å; L175-M200 HydrophobicContact CD1-SD 4.13Å; L175-V202 HydrophobicContact CD1-CG2 3.67Å; L175-F259 HydrophobicContact CB-CD1 4.33Å; L175-F259 HydrophobicContact CB-CE1 4.27Å; L175-F259 HydrophobicContact CD1-CD1 4.45Å; L175-P261 HydrophobicContact CB-CB 3.73Å; L175-P261 HydrophobicContact CB-CG 4.05Å; L175-P261 HydrophobicContact CD2-CG 4.24Å; L175-A263 PolarHBondContact N-O 2.87Å; L175-I264 HydrophobicContact CB-CG2 4.43Å; L175-I264 HydrophobicContact CD2-CG2 4.48Å; L175-I264 CarbonylContact O-C 3.54Å; L175-I264 VanDerWaalsContact O-CA 3.26Å; L175-I264 WeakPolarHBondContact O-CA 3.34Å; L175-V265 PolarHBondContact O-N 2.83Å
176Y98.4Very high94.6Very high2 Ų231.6 Ų31.61%0.00814%0.14CC..EExtended strand (participates in β ladder)trans-100.4120.2169.9177.6-107.9000108.7C160 I164 D178 V189 M200 T201 V202 V265 Q267C160-Y176 HydrophobicContact CB-CE2 4Å; I164-Y176 HydrophobicContact CD1-CD2 3.87Å; I164-Y176 HydrophobicContact CD1-CG 4.08Å; Y176-D178 HydrophobicContact CD1-CB 4.44Å; Y176-D178 HydrophobicContact CE1-CB 3.72Å; Y176-D178 PolarHBondContact OH-OD2 2.79Å; Y176-V189 HydrophobicContact CD1-CB 4.49Å; Y176-V189 HydrophobicContact CD1-CG1 3.63Å; Y176-V189 HydrophobicContact CD2-CG1 4.38Å; Y176-V189 HydrophobicContact CE1-CB 3.98Å; Y176-V189 HydrophobicContact CE1-CG1 3.52Å; Y176-V189 HydrophobicContact CE1-CG2 4.27Å; Y176-V189 HydrophobicContact CE2-CG1 4.32Å; Y176-V189 HydrophobicContact CG-CG1 4.05Å; Y176-M200 PolarHBondContact N-O 3.22Å; Y176-T201 HydrophobicContact CD1-CG2 4.07Å; Y176-T201 CarbonylContact O-C 3.58Å; Y176-V202 PolarHBondContact O-N 2.9Å; Y176-V265 CarbonylContact C-O 3.59Å; Y176-V265 WeakPolarHBondContact CA-O 3.36Å; Y176-V265 HydrophobicContact CD2-CB 3.96Å; Y176-V265 HydrophobicContact CD2-CG1 3.84Å; Y176-V265 HydrophobicContact CE2-CG1 4.09Å; Y176-Q267 HydrophobicContact CE2-CB 4.1Å; Y176-Q267 WeakPolarHBondContact OH-CB 3.47Å
177V98.1Very high92.7Very high2 Ų231 Ų311%0.01214%0.143CC..EExtended strand (participates in β ladder)trans-115122.3177.2-175.60000108.4L175 L179 V202 F204 I264 V265 V266 Q267 I295L175-V177 HydrophobicContact CD1-CG2 4.47Å; L175-V177 HydrophobicContact CD2-CG2 3.91Å; L175-V177 HydrophobicContact CG-CG2 3.82Å; V177-L179 HydrophobicContact CG1-CD2 3.67Å; V177-L179 HydrophobicContact CG1-CG 4.32Å; V177-V202 CarbonylContact C-O 3.56Å; V177-V202 WeakPolarHBondContact CA-O 3.41Å; V177-F204 HydrophobicContact CG1-CE2 4.27Å; V177-I264 HydrophobicContact CG2-CG2 4.27Å; V177-V265 PolarHBondContact N-O 3.1Å; V177-V266 HydrophobicContact CB-CG1 4.44Å; V177-V266 CarbonylContact O-C 3.58Å; V177-V266 VanDerWaalsContact O-CA 3.29Å; V177-V266 WeakPolarHBondContact O-CA 3.46Å; V177-Q267 PolarHBondContact O-N 3.13Å; V177-I295 HydrophobicContact CB-CD1 4.5Å; V177-I295 HydrophobicContact CG1-CD1 4.16Å
178D98.3Very high92.1Very high0 Ų031 Ų310%014%0.143CC..EExtended strand (participates in β ladder)trans-114.5114.9-176.8-163.3-23.4000110.1H144 Y176 D180 G184 V202 F204 Q267H144-D178 IonicContact CE1-OD1 3.14Å; H144-D178 IonicContact CE1-OD2 3.43Å; H144-D178 IonicContact CG-OD2 3.1Å; H144-D178 IonicContact ND1-OD1 3.12Å; H144-D178 IonicContact ND1-OD2 2.89Å; H144-D178 PolarHBondContact ND1-OD2 2.57Å; Y176-D178 HydrophobicContact CD1-CB 4.44Å; Y176-D178 HydrophobicContact CE1-CB 3.72Å; Y176-D178 PolarHBondContact OH-OD2 2.79Å; D178-D180 VanDerWaalsContact OD1-CB 3.23Å; D178-D180 WeakPolarHBondContact OD1-CB 3.45Å; D178-D180 PolarHBondContact OD1-N 2.98Å; D178-G184 VanDerWaalsContact OD2-CA 3.29Å; D178-G184 WeakPolarHBondContact OD2-CA 3.26Å; D178-V202 PolarHBondContact N-O 3Å; D178-F204 PolarHBondContact O-N 3.46Å; D178-F204 VanDerWaalsContact O-N 3.1Å; D178-Q267 PolarHBondContact OD1-OE1 2.82Å
179L98.2Very high91.8Very high2 Ų227.4 Ų27.41%0.0113%0.13CC..  trans-107.76.4-179.9-50.5-169.6000112.5V177 F204 F244 Q267 L268 Y288V177-L179 HydrophobicContact CG1-CD2 3.67Å; V177-L179 HydrophobicContact CG1-CG 4.32Å; L179-F204 HydrophobicContact CD2-CD2 3.68Å; L179-F204 HydrophobicContact CD2-CE2 4.1Å; L179-F204 HydrophobicContact CD2-CG 4.43Å; L179-F244 HydrophobicContact CD2-CE1 4.49Å; L179-F244 HydrophobicContact CD2-CZ 4.06Å; L179-Q267 PolarHBondContact N-O 2.87Å; L179-Q267 VanDerWaalsContact N-O 3.1Å; L179-L268 HydrophobicContact CD1-CD2 3.85Å; L179-Y288 HydrophobicContact CB-CE1 4.39Å
180D98.3Very high91.5Very high2 Ų221.9 Ų21.91%0.01110%0.104CC..SBendtrans-59.8151.7168.3-155.9-81000110.5H144 D178 H182 F204 Q267 G269 G308H144-D180 VanDerWaalsContact CE1-CB 3.47Å; H144-D180 WeakPolarHBondContact CE1-CB 3.34Å; H144-D180 IonicContact CE1-OD1 2.91Å; H144-D180 IonicContact NE2-OD1 3.02Å; D178-D180 VanDerWaalsContact OD1-CB 3.23Å; D178-D180 WeakPolarHBondContact OD1-CB 3.45Å; D178-D180 PolarHBondContact OD1-N 2.98Å; D180-H182 PolarHBondContact O-N 3.43Å; D180-H182 WeakPolarHBondContact OD1-CB 3.32Å; D180-H182 IonicContact OD1-CG 3.79Å; D180-H182 PolarHBondContact OD1-N 3Å; D180-H182 IonicContact OD1-ND1 3.66Å; D180-H182 PolarHBondContact OD1-ND1 3.11Å; D180-F204 VanDerWaalsContact O-O 3.1Å; D180-Q267 PolarHBondContact OD2-NE2 3.36Å; D180-G269 WeakPolarHBondContact OD2-CA 3.29Å; D180-G308 WeakPolarHBondContact OD2-CA 3.5Å; D180-G308 PolarHBondContact OD2-N 2.98Å
181V97.9Very high91.2Very high0 Ų018.9 Ų18.90%010%0.096CC..SBendtrans-71.7-20.5177.478.90000113H205 L206 F211 D271 A280 F281V181-H205 CarbonylContact O-C 3.53Å; V181-H205 WeakPolarHBondContact O-CA 3.2Å; V181-H205 VanDerWaalsContact O-CB 3.29Å; V181-H205 WeakPolarHBondContact O-CB 3.24Å; V181-L206 HydrophobicContact CG2-CB 3.94Å; V181-L206 PolarHBondContact O-N 3.33Å; V181-F211 HydrophobicContact CG1-CE1 4.4Å; V181-F211 HydrophobicContact CG1-CZ 3.96Å; V181-F211 HydrophobicContact CG2-CZ 4.47Å; V181-D271 HydrophobicContact CG1-CB 4.12Å; V181-D271 VanDerWaalsContact CG1-CG 3.43Å; V181-D271 WeakPolarHBondContact CG1-OD1 2.96Å; V181-D271 PolarHBondContact N-OD1 3.31Å; V181-A280 HydrophobicContact CB-CB 4.3Å; V181-A280 HydrophobicContact CG1-CB 4.19Å; V181-A280 HydrophobicContact CG2-CB 3.29Å; V181-F281 HydrophobicContact CB-CD2 4.49Å; V181-F281 HydrophobicContact CB-CE2 4.44Å; V181-F281 HydrophobicContact CG2-CD1 4.24Å; V181-F281 HydrophobicContact CG2-CD2 3.69Å; V181-F281 HydrophobicContact CG2-CE1 4.18Å; V181-F281 HydrophobicContact CG2-CE2 3.63Å; V181-F281 HydrophobicContact CG2-CG 3.99Å; V181-F281 HydrophobicContact CG2-CZ 3.88Å
182H97.6Very high91Very high16 Ų1619.3 Ų19.37%0.07411%0.106CC..SBendtrans-89.8147.6174.9-51.288.3000110.6H144 H145 D180 G184 F211 Y212 D271 N278H144-H182 PolarHBondContact CE1-O 3.47Å; H145-H182 WeakPolarHBondContact NE2-CB 3.44Å; D180-H182 PolarHBondContact O-N 3.43Å; D180-H182 WeakPolarHBondContact OD1-CB 3.32Å; D180-H182 IonicContact OD1-CG 3.79Å; D180-H182 PolarHBondContact OD1-N 3Å; D180-H182 IonicContact OD1-ND1 3.66Å; D180-H182 PolarHBondContact OD1-ND1 3.11Å; H182-G184 PolarHBondContact O-N 3.03Å; H182-F211 AromaticContact CD2-CE1 3.56Å; H182-F211 AromaticContact CD2-CZ 3.66Å; H182-F211 AromaticContact NE2-CE1 3.98Å; H182-F211 AromaticContact NE2-CZ 3.56Å; H182-Y212 PolarHBondContact CD2-O 2.54Å; H182-D271 IonicContact CE1-OD2 2.68Å; H182-D271 PolarHBondContact CE1-OD2 3.35Å; H182-D271 IonicContact ND1-OD2 3.97Å; H182-D271 PolarHBondContact ND1-OD2 3.48Å; H182-D271 VanDerWaalsContact ND1-OD2 3.12Å; H182-N278 PolarHBondContact CE1-ND2 3.39Å
183H97Very high90.9Very high1 Ų113.5 Ų13.51%0.0058%0.081CC..  trans-64.9128.2174.3178.6-146000110.2H145 D185 E190 H205 P213 S215 G216 N232H145-H183 PolarHBondContact CE1-O 3.2Å; H183-D185 WeakPolarHBondContact ND1-CA 3.4Å; H183-D185 PolarHBondContact O-N 3.47Å; H183-E190 IonicContact CE1-OE2 3.09Å; H183-E190 IonicContact NE2-OE2 3.12Å; H183-E190 PolarHBondContact NE2-OE2 2.85Å; H183-H205 HydrophobicContact CB-CB 4.2Å; H183-H205 AromaticContact CD2-CE1 3.36Å; H183-H205 PolarHBondContact CD2-CE1 2.82Å; H183-H205 AromaticContact CD2-ND1 3.51Å; H183-H205 AromaticContact CG-CE1 3.65Å; H183-H205 AromaticContact CG-ND1 3.82Å; H183-P213 HydrophobicContact CB-CG 3.97Å; H183-S215 PolarHBondContact ND1-O 2.98Å; H183-S215 PolarHBondContact ND1-OG 3.15Å; H183-G216 WeakPolarHBondContact CE1-CA 3.38Å; H183-G216 PolarHBondContact CE1-N 2.86Å; H183-G216 VanDerWaalsContact ND1-CA 3.29Å; H183-G216 WeakPolarHBondContact ND1-CA 3.39Å; H183-G216 PolarHBondContact ND1-N 2.89Å; H183-G216 VanDerWaalsContact ND1-N 3.18Å; H183-N232 PolarHBondContact CD2-OD1 2.87Å; H183-N232 PolarHBondContact NE2-OD1 2.94Å
184G86.5Confident90.8Very high3 Ų313.3 Ų13.33%0.0318%0.082CC..  trans-68.270.5168.700000111.9D178 H182 E190D178-G184 VanDerWaalsContact OD2-CA 3.29Å; D178-G184 WeakPolarHBondContact OD2-CA 3.26Å; H182-G184 PolarHBondContact O-N 3.03Å; G184-E190 WeakPolarHBondContact O-CB 3.39Å; G184-E190 PolarHBondContact O-N 2.94Å
185D76.9Confident90.6Very high2 Ų216 Ų161%0.01110%0.104CC..  trans-61.9164.4-142.563.256.3000119.7H145 H183 A187 S188 E190 P213 S215H145-D185 IonicContact CE1-OD2 3.95Å; H145-D185 IonicContact CG-OD2 3.85Å; H145-D185 IonicContact ND1-OD2 3.62Å; H145-D185 PolarHBondContact ND1-OD2 2.89Å; H183-D185 WeakPolarHBondContact ND1-CA 3.4Å; H183-D185 PolarHBondContact O-N 3.47Å; D185-A187 PolarHBondContact O-N 2.82Å; D185-A187 VanDerWaalsContact OD1-C 3.24Å; D185-A187 VanDerWaalsContact OD1-CA 3.24Å; D185-A187 WeakPolarHBondContact OD1-CA 3.34Å; D185-A187 WeakPolarHBondContact OD1-CB 3.23Å; D185-A187 PolarHBondContact OD1-N 2.57Å; D185-S188 PolarHBondContact N-OG 3.37Å; D185-S188 VanDerWaalsContact N-OG 3.11Å; D185-S188 PolarHBondContact O-N 3.47Å; D185-S188 PolarHBondContact O-OG 3.46Å; D185-S188 VanDerWaalsContact OD1-CB 3.32Å; D185-S188 WeakPolarHBondContact OD1-CB 3.42Å; D185-S188 PolarHBondContact OD1-N 2.88Å; D185-S188 PolarHBondContact OD1-OG 3.29Å; D185-S188 VanDerWaalsContact OD1-OG 3.06Å; D185-E190 WeakPolarHBondContact O-CB 3.31Å; D185-E190 PolarHBondContact O-N 2.95Å; D185-P213 HydrophobicContact CB-CB 4.14Å; D185-P213 HydrophobicContact CB-CG 3.53Å; D185-S215 WeakPolarHBondContact CB-OG 3.33Å
186G56.7Low90.4Very high27 Ų2717.3 Ų17.328%0.27811%0.114SC..THydrogen-bonded Turntrans-66.416.2170.400000114.2E191G186-E191 WeakPolarHBondContact O-CB 3.29Å; G186-E191 VanDerWaalsContact O-OE2 3.12Å
187A58.6Low90.2Very high29 Ų2918 Ų1824%0.2412%0.12CC..THydrogen-bonded Turntrans-124.10.2163.300000112.9R147 D185R147-A187 VanDerWaalsContact CG-O 3.23Å; R147-A187 WeakPolarHBondContact CG-O 3.47Å; D185-A187 PolarHBondContact O-N 2.82Å; D185-A187 VanDerWaalsContact OD1-C 3.24Å; D185-A187 VanDerWaalsContact OD1-CA 3.24Å; D185-A187 WeakPolarHBondContact OD1-CA 3.34Å; D185-A187 WeakPolarHBondContact OD1-CB 3.23Å; D185-A187 PolarHBondContact OD1-N 2.57Å
188S85.5Confident90.2Very high0 Ų020.9 Ų20.90%014%0.135CC..THydrogen-bonded Turntrans-126.9-103.4-17570.50000112.6H144 H145 D185 A192H144-S188 WeakPolarHBondContact O-CB 3.47Å; H144-S188 PolarHBondContact O-OG 3.22Å; H145-S188 WeakPolarHBondContact O-CB 3.21Å; D185-S188 PolarHBondContact N-OG 3.37Å; D185-S188 VanDerWaalsContact N-OG 3.11Å; D185-S188 PolarHBondContact O-N 3.47Å; D185-S188 PolarHBondContact O-OG 3.46Å; D185-S188 VanDerWaalsContact OD1-CB 3.32Å; D185-S188 WeakPolarHBondContact OD1-CB 3.42Å; D185-S188 PolarHBondContact OD1-N 2.88Å; D185-S188 PolarHBondContact OD1-OG 3.29Å; D185-S188 VanDerWaalsContact OD1-OG 3.06Å; S188-A192 VanDerWaalsContact O-CB 3.3Å; S188-A192 WeakPolarHBondContact O-CB 3.28Å; S188-A192 PolarHBondContact O-N 3.28Å
189V91.4Very high90.1Very high0 Ų021 Ų210%014%0.136CC..Hα-helixtrans-71.8-46.9-177.7-173.70000110.7H144 C160 V161 I164 Y176 A192 F193 T201H144-V189 HydrophobicContact CB-CG2 3.85Å; H144-V189 WeakPolarHBondContact O-CG2 3.24Å; C160-V189 HydrophobicContact CB-CG2 3.78Å; V161-V189 HydrophobicContact CG2-CB 4.39Å; V161-V189 HydrophobicContact CG2-CG1 4.38Å; V161-V189 HydrophobicContact CG2-CG2 4.2Å; I164-V189 HydrophobicContact CD1-CG1 4.13Å; Y176-V189 HydrophobicContact CD1-CB 4.49Å; Y176-V189 HydrophobicContact CD1-CG1 3.63Å; Y176-V189 HydrophobicContact CD2-CG1 4.38Å; Y176-V189 HydrophobicContact CE1-CB 3.98Å; Y176-V189 HydrophobicContact CE1-CG1 3.52Å; Y176-V189 HydrophobicContact CE1-CG2 4.27Å; Y176-V189 HydrophobicContact CE2-CG1 4.32Å; Y176-V189 HydrophobicContact CG-CG1 4.05Å; V189-A192 PolarHBondContact O-N 3.15Å; V189-F193 HydrophobicContact CG1-CD2 4.37Å; V189-F193 HydrophobicContact CG1-CE2 4.41Å; V189-F193 VanDerWaalsContact O-CD2 3.26Å; V189-F193 WeakPolarHBondContact O-CD2 3.4Å; V189-T201 HydrophobicContact CG1-CG2 4.36Å
190E92.7Very high90.1Very high6 Ų620.9 Ų20.93%0.02814%0.136CC..Hα-helixtrans-61.3-45.5175.9179.3174116.400110.8H183 G184 D185 A192 F193 I194 A230 N232H183-E190 IonicContact CE1-OE2 3.09Å; H183-E190 IonicContact NE2-OE2 3.12Å; H183-E190 PolarHBondContact NE2-OE2 2.85Å; G184-E190 WeakPolarHBondContact O-CB 3.39Å; G184-E190 PolarHBondContact O-N 2.94Å; D185-E190 WeakPolarHBondContact O-CB 3.31Å; D185-E190 PolarHBondContact O-N 2.95Å; E190-A192 PolarHBondContact O-N 2.9Å; E190-F193 CarbonylContact O-C 3.57Å; E190-F193 PolarHBondContact O-N 2.88Å; E190-F193 VanDerWaalsContact O-N 3.09Å; E190-I194 WeakPolarHBondContact O-CA 3.43Å; E190-I194 WeakPolarHBondContact O-CB 3.48Å; E190-I194 PolarHBondContact O-N 2.9Å; E190-A230 HydrophobicContact CG-CB 3.96Å; E190-A230 WeakPolarHBondContact OE2-CB 3.35Å; E190-N232 PolarHBondContact OE2-ND2 3.4Å; E190-N232 PolarHBondContact OE2-OD1 3.05Å
191E92.5Very high90Very high93 Ų9321.2 Ų21.244%0.43514%0.137SC..Hα-helixtrans-60.5-43.5179.1-172.355.1-16800113.1G186 F193 I194G186-E191 WeakPolarHBondContact O-CB 3.29Å; G186-E191 VanDerWaalsContact O-OE2 3.12Å; E191-F193 PolarHBondContact O-N 2.81Å; E191-I194 WeakPolarHBondContact O-CG2 3.36Å; E191-I194 PolarHBondContact O-N 2.84Å; E191-I194 WeakPolarHBondContact OE2-CD1 3.49Å
192A94Very high90Very high38 Ų3821.2 Ų21.231%0.31414%0.137SC..Hα-helixtrans-56.1-23.5179.500000112.4F66 V161 S188 V189 E190F66-A192 HydrophobicContact CE2-CB 3.84Å; F66-A192 HydrophobicContact CZ-CB 4.33Å; V161-A192 HydrophobicContact CB-CB 4.49Å; V161-A192 HydrophobicContact CG1-CB 3.94Å; V161-A192 HydrophobicContact CG2-CB 3.63Å; S188-A192 VanDerWaalsContact O-CB 3.3Å; S188-A192 WeakPolarHBondContact O-CB 3.28Å; S188-A192 PolarHBondContact O-N 3.28Å; V189-A192 PolarHBondContact O-N 3.15Å; E190-A192 PolarHBondContact O-N 2.9Å
193F96Very high90Very high20 Ų2020.6 Ų20.69%0.08814%0.135CC..Hα-helixtrans-125.39.1-177.9-56.4-63.1000114.5V161 I164 L165 V189 E190 E191 A195 S196 V199V161-F193 HydrophobicContact CB-CE2 4.46Å; V161-F193 HydrophobicContact CG1-CE2 4.28Å; V161-F193 HydrophobicContact CG1-CZ 4.02Å; V161-F193 HydrophobicContact CG2-CE2 4.11Å; I164-F193 HydrophobicContact CB-CE2 4.03Å; I164-F193 HydrophobicContact CB-CZ 3.8Å; I164-F193 HydrophobicContact CD1-CD2 4.36Å; I164-F193 HydrophobicContact CD1-CE2 3.65Å; I164-F193 HydrophobicContact CD1-CZ 4.32Å; I164-F193 HydrophobicContact CG1-CE2 4.46Å; I164-F193 HydrophobicContact CG2-CE1 3.94Å; I164-F193 HydrophobicContact CG2-CE2 3.77Å; I164-F193 HydrophobicContact CG2-CZ 3.38Å; L165-F193 HydrophobicContact CD2-CE1 4.14Å; L165-F193 HydrophobicContact CD2-CZ 4.43Å; L165-F193 HydrophobicContact CG-CZ 4.39Å; V189-F193 HydrophobicContact CG1-CD2 4.37Å; V189-F193 HydrophobicContact CG1-CE2 4.41Å; V189-F193 VanDerWaalsContact O-CD2 3.26Å; V189-F193 WeakPolarHBondContact O-CD2 3.4Å; E190-F193 CarbonylContact O-C 3.57Å; E190-F193 PolarHBondContact O-N 2.88Å; E190-F193 VanDerWaalsContact O-N 3.09Å; E191-F193 PolarHBondContact O-N 2.81Å; F193-A195 PolarHBondContact O-N 2.82Å; F193-S196 VanDerWaalsContact O-CB 3.31Å; F193-S196 WeakPolarHBondContact O-CB 3.39Å; F193-S196 PolarHBondContact O-N 3.34Å; F193-V199 HydrophobicContact CB-CB 3.87Å; F193-V199 HydrophobicContact CB-CG1 3.97Å; F193-V199 HydrophobicContact CD1-CB 3.88Å; F193-V199 HydrophobicContact CD1-CG1 4.16Å; F193-V199 HydrophobicContact CD1-CG2 3.7Å; F193-V199 HydrophobicContact CD2-CB 4.31Å; F193-V199 HydrophobicContact CD2-CG1 3.71Å; F193-V199 HydrophobicContact CE1-CG2 3.98Å; F193-V199 HydrophobicContact CE2-CG1 4.26Å; F193-V199 HydrophobicContact CG-CB 3.73Å; F193-V199 HydrophobicContact CG-CG1 3.65Å; F193-V199 HydrophobicContact CG-CG2 4.07Å
194I95.1Very high90.1Very high35 Ų3520.7 Ų20.718%0.17914%0.135CC..THydrogen-bonded Turntrans-59-27.3-170.1-161.2174000113.7E190 E191 V223 G226E190-I194 WeakPolarHBondContact O-CA 3.43Å; E190-I194 WeakPolarHBondContact O-CB 3.48Å; E190-I194 PolarHBondContact O-N 2.9Å; E191-I194 WeakPolarHBondContact O-CG2 3.36Å; E191-I194 PolarHBondContact O-N 2.84Å; E191-I194 WeakPolarHBondContact OE2-CD1 3.49Å; I194-V223 HydrophobicContact CD1-CG1 4.26Å; I194-V223 HydrophobicContact CD1-CG2 4.48Å; I194-V223 HydrophobicContact CG1-CG1 4.43Å; I194-V223 HydrophobicContact CG1-CG2 4.13Å; I194-V223 HydrophobicContact CG2-CG2 4.01Å; I194-V223 PolarHBondContact O-N 3.36Å; I194-G226 WeakPolarHBondContact O-CA 3.42Å
195A94.3Very high90.6Very high56 Ų5620.5 Ų20.546%0.46313%0.134SC..THydrogen-bonded Turntrans-102.16.7178.700000114.1F193 V223 R225 G226F193-A195 PolarHBondContact O-N 2.82Å; A195-V223 WeakPolarHBondContact CA-O 3.17Å; A195-V223 HydrophobicContact CB-CG2 4.23Å; A195-R225 WeakPolarHBondContact O-CB 3.34Å; A195-G226 VanDerWaalsContact C-N 3.31Å; A195-G226 PolarHBondContact O-N 2.99Å
196S94.7Very high91.6Very high29 Ų2920.6 Ų20.620%0.20314%0.135CC..  trans-102.8129-175.1-1770000112F193 N198 G226F193-S196 VanDerWaalsContact O-CB 3.31Å; F193-S196 WeakPolarHBondContact O-CB 3.39Å; F193-S196 PolarHBondContact O-N 3.34Å; S196-N198 VanDerWaalsContact C-N 3.27Å; S196-N198 PolarHBondContact OG-N 3.27Å; S196-N198 VanDerWaalsContact OG-N 3.13Å; S196-G226 WeakPolarHBondContact O-CA 3.22Å
197A95.1Very high93.6Very high17 Ų1721.2 Ų21.214%0.1413%0.131CC..SBendtrans-83.5-2.7167.300000113.2R225 Y229 F259A197-R225 WeakPolarHBondContact CB-O 3.4Å; A197-Y229 HydrophobicContact CB-CD2 4.24Å; A197-Y229 HydrophobicContact CB-CE1 4.06Å; A197-Y229 HydrophobicContact CB-CE2 3.75Å; A197-Y229 VanDerWaalsContact O-CE1 3.25Å; A197-Y229 WeakPolarHBondContact O-CE1 3.43Å; A197-F259 WeakPolarHBondContact O-CE2 3.25Å
198N96.4Very high95.3Very high62 Ų6222.1 Ų22.133%0.33213%0.13SC..SBendtrans-98.9-10.2-175-67.5-47.1000112.9K172 R173 I174 S196K172-N198 WeakPolarHBondContact O-CB 3.41Å; R173-N198 VanDerWaalsContact CA-O 3.27Å; R173-N198 WeakPolarHBondContact CA-O 3.18Å; I174-N198 PolarHBondContact N-O 2.91Å; S196-N198 VanDerWaalsContact C-N 3.27Å; S196-N198 PolarHBondContact OG-N 3.27Å; S196-N198 VanDerWaalsContact OG-N 3.13Å
199V97.3Very high95.8Very high3 Ų328.8 Ų28.82%0.01817%0.174CC..EExtended strand (participates in β ladder)trans-131123.3174.71800000106.2I164 R168 I174 F193I164-V199 HydrophobicContact CG2-CG1 4.06Å; I164-V199 HydrophobicContact CG2-CG2 3.79Å; R168-V199 HydrophobicContact CG-CG2 4.37Å; I174-V199 HydrophobicContact CB-CG2 4.33Å; I174-V199 WeakPolarHBondContact O-CA 3.46Å; F193-V199 HydrophobicContact CB-CB 3.87Å; F193-V199 HydrophobicContact CB-CG1 3.97Å; F193-V199 HydrophobicContact CD1-CB 3.88Å; F193-V199 HydrophobicContact CD1-CG1 4.16Å; F193-V199 HydrophobicContact CD1-CG2 3.7Å; F193-V199 HydrophobicContact CD2-CB 4.31Å; F193-V199 HydrophobicContact CD2-CG1 3.71Å; F193-V199 HydrophobicContact CE1-CG2 3.98Å; F193-V199 HydrophobicContact CE2-CG1 4.26Å; F193-V199 HydrophobicContact CG-CB 3.73Å; F193-V199 HydrophobicContact CG-CG1 3.65Å; F193-V199 HydrophobicContact CG-CG2 4.07Å
200M97.2Very high95.9Very high0 Ų032.3 Ų32.30%021%0.21CC..EExtended strand (participates in β ladder)trans-105.4124.4174.2175.6174.1-78.700108.2I174 L175 Y176 V202 Y229 V231 L255 F259 L380I174-M200 PolarHBondContact O-N 3.42Å; L175-M200 HydrophobicContact CD1-CB 4.08Å; L175-M200 HydrophobicContact CD1-CG 3.96Å; L175-M200 HydrophobicContact CD1-SD 4.13Å; Y176-M200 PolarHBondContact N-O 3.22Å; M200-V202 HydrophobicContact CG-CG2 4.22Å; M200-Y229 CarbonylContact C-O 3.52Å; M200-Y229 WeakPolarHBondContact CA-O 2.98Å; M200-Y229 HydrophobicContact CB-CD1 4.45Å; M200-Y229 HydrophobicContact CE-CD1 3.84Å; M200-Y229 HydrophobicContact CE-CE1 4.41Å; M200-Y229 HydrophobicContact CE-CG 4.44Å; M200-Y229 WeakPolarHBondContact CG-O 3.32Å; M200-V231 HydrophobicContact CG-CG2 4.48Å; M200-V231 HydrophobicContact SD-CG2 4.44Å; M200-L255 HydrophobicContact SD-CD2 3.62Å; M200-F259 HydrophobicContact CB-CD1 3.78Å; M200-F259 HydrophobicContact CB-CD2 3.8Å; M200-F259 HydrophobicContact CB-CE1 3.68Å; M200-F259 HydrophobicContact CB-CE2 3.69Å; M200-F259 HydrophobicContact CB-CG 3.85Å; M200-F259 HydrophobicContact CB-CZ 3.62Å; M200-F259 HydrophobicContact CE-CB 3.68Å; M200-F259 HydrophobicContact CE-CD2 3.71Å; M200-F259 HydrophobicContact CE-CG 3.81Å; M200-F259 HydrophobicContact CG-CG 4.46Å; M200-F259 HydrophobicContact SD-CB 3.67Å; M200-F259 HydrophobicContact SD-CD1 4.21Å; M200-F259 HydrophobicContact SD-CD2 4.19Å; M200-F259 HydrophobicContact SD-CG 3.77Å; M200-L380 HydrophobicContact CE-CD1 3.69Å
201T97.7Very high96Very high8 Ų833.1 Ų33.15%0.04921%0.213CC..EExtended strand (participates in β ladder)trans-98.2138.8174.556.60000109.8Y176 V189 Y229 V231Y176-T201 HydrophobicContact CD1-CG2 4.07Å; Y176-T201 CarbonylContact O-C 3.58Å; V189-T201 HydrophobicContact CG1-CG2 4.36Å; T201-Y229 PolarHBondContact N-O 2.86Å; T201-V231 PolarHBondContact O-N 3.14Å
202V97.4Very high96.2Very high0 Ų032.6 Ų32.60%021%0.208CC..EExtended strand (participates in β ladder)trans-136.1121178.4-171.80000107.6L175 Y176 V177 D178 M200 F204 V231 L255L175-V202 HydrophobicContact CD1-CG2 3.67Å; Y176-V202 PolarHBondContact O-N 2.9Å; V177-V202 CarbonylContact C-O 3.56Å; V177-V202 WeakPolarHBondContact CA-O 3.41Å; D178-V202 PolarHBondContact N-O 3Å; M200-V202 HydrophobicContact CG-CG2 4.22Å; V202-F204 HydrophobicContact CG1-CD2 4.36Å; V202-F204 HydrophobicContact CG1-CE2 3.6Å; V202-F204 HydrophobicContact CG1-CZ 4.07Å; V202-V231 VanDerWaalsContact CA-O 3.28Å; V202-V231 WeakPolarHBondContact CA-O 3.32Å; V202-V231 HydrophobicContact CB-CB 4.42Å; V202-V231 HydrophobicContact CG1-CB 4.21Å; V202-V231 HydrophobicContact CG1-CG1 4.2Å; V202-V231 HydrophobicContact CG2-CB 4.12Å; V202-L255 HydrophobicContact CB-CD1 4.35Å; V202-L255 HydrophobicContact CG1-CD1 3.96Å; V202-L255 HydrophobicContact CG2-CD1 3.6Å; V202-L255 HydrophobicContact CG2-CD2 4.08Å; V202-L255 HydrophobicContact CG2-CG 4.49Å
203S97.9Very high96.2Very high4 Ų432 Ų323%0.02820%0.201CC..EExtended strand (participates in β ladder)trans-131133.2-177.8-175.50000111.9H205 V231 V233S203-H205 WeakPolarHBondContact CB-ND1 3.41Å; S203-H205 PolarHBondContact OG-ND1 2.97Å; S203-V231 PolarHBondContact N-O 3.12Å; S203-V233 WeakPolarHBondContact O-CB 3.43Å; S203-V233 PolarHBondContact O-N 2.92Å
204F98Very high96.1Very high2 Ų235 Ų351%0.00922%0.223CC..EExtended strand (participates in β ladder)trans-113.692.1178.6-60.8-102.7000109.6V177 D178 L179 D180 V202 V233 L235 F244 I247 L248 I251V177-F204 HydrophobicContact CG1-CE2 4.27Å; D178-F204 PolarHBondContact O-N 3.46Å; D178-F204 VanDerWaalsContact O-N 3.1Å; L179-F204 HydrophobicContact CD2-CD2 3.68Å; L179-F204 HydrophobicContact CD2-CE2 4.1Å; L179-F204 HydrophobicContact CD2-CG 4.43Å; D180-F204 VanDerWaalsContact O-O 3.1Å; V202-F204 HydrophobicContact CG1-CD2 4.36Å; V202-F204 HydrophobicContact CG1-CE2 3.6Å; V202-F204 HydrophobicContact CG1-CZ 4.07Å; F204-V233 HydrophobicContact CD1-CB 3.84Å; F204-V233 HydrophobicContact CD1-CG1 3.92Å; F204-V233 HydrophobicContact CD1-CG2 3.86Å; F204-V233 HydrophobicContact CE1-CB 4.29Å; F204-V233 HydrophobicContact CE1-CG1 4.28Å; F204-V233 HydrophobicContact CE1-CG2 3.85Å; F204-V233 HydrophobicContact CG-CB 4.28Å; F204-V233 HydrophobicContact CG-CG2 4.31Å; F204-V233 HydrophobicContact CZ-CG2 4.28Å; F204-L235 HydrophobicContact CB-CD1 4.08Å; F204-F244 HydrophobicContact CB-CE2 3.98Å; F204-F244 HydrophobicContact CB-CZ 4.18Å; F204-F244 HydrophobicContact CG-CZ 4.42Å; F204-I247 HydrophobicContact CD1-CG2 4.33Å; F204-I247 HydrophobicContact CE1-CG2 4Å; F204-L248 HydrophobicContact CE1-CD1 4.41Å; F204-L248 HydrophobicContact CE2-CD1 4.14Å; F204-L248 HydrophobicContact CZ-CD1 3.75Å; F204-I251 HydrophobicContact CE1-CD1 4.04Å; F204-I251 HydrophobicContact CZ-CD1 4.44Å; F204-I251 HydrophobicContact CZ-CG2 4.42Å
205H98.2Very high96.1Very high0 Ų034.8 Ų34.80%023%0.225CC..EExtended strand (participates in β ladder)trans-132.8160.8-166.550.6-97.9000112.4V181 H183 S203 G216 N232 V233 L235V181-H205 CarbonylContact O-C 3.53Å; V181-H205 WeakPolarHBondContact O-CA 3.2Å; V181-H205 VanDerWaalsContact O-CB 3.29Å; V181-H205 WeakPolarHBondContact O-CB 3.24Å; H183-H205 HydrophobicContact CB-CB 4.2Å; H183-H205 AromaticContact CD2-CE1 3.36Å; H183-H205 PolarHBondContact CD2-CE1 2.82Å; H183-H205 AromaticContact CD2-ND1 3.51Å; H183-H205 AromaticContact CG-CE1 3.65Å; H183-H205 AromaticContact CG-ND1 3.82Å; S203-H205 WeakPolarHBondContact CB-ND1 3.41Å; S203-H205 PolarHBondContact OG-ND1 2.97Å; H205-G216 PolarHBondContact NE2-O 3.33Å; H205-N232 PolarHBondContact CE1-OD1 2.85Å; H205-V233 PolarHBondContact N-O 2.92Å; H205-L235 WeakPolarHBondContact O-CB 3.36Å; H205-L235 PolarHBondContact O-N 2.88Å
206L98Very high96.1Very high4 Ų432.1 Ų32.12%0.02120%0.203CC..EExtended strand (participates in β ladder)trans-72.9126.1170.3175.960.1000109.2V181 E208 F211 L235 R236 R237 A280 F281V181-L206 HydrophobicContact CG2-CB 3.94Å; V181-L206 PolarHBondContact O-N 3.33Å; L206-E208 HydrophobicContact CD1-CG 3.75Å; L206-E208 HydrophobicContact CG-CG 4.42Å; L206-F211 HydrophobicContact CB-CD1 3.77Å; L206-F211 HydrophobicContact CB-CE1 3.7Å; L206-F211 HydrophobicContact CB-CG 4.39Å; L206-F211 HydrophobicContact CB-CZ 4.26Å; L206-F211 HydrophobicContact CD2-CB 4.47Å; L206-F211 HydrophobicContact CD2-CD1 3.89Å; L206-F211 HydrophobicContact CD2-CD2 3.55Å; L206-F211 HydrophobicContact CD2-CE1 3.98Å; L206-F211 HydrophobicContact CD2-CE2 3.65Å; L206-F211 HydrophobicContact CD2-CG 3.68Å; L206-F211 HydrophobicContact CD2-CZ 3.87Å; L206-F211 HydrophobicContact CG-CB 4.46Å; L206-F211 HydrophobicContact CG-CD1 3.77Å; L206-F211 HydrophobicContact CG-CD2 4.29Å; L206-F211 HydrophobicContact CG-CE1 4.08Å; L206-F211 HydrophobicContact CG-CG 3.89Å; L206-F211 HydrophobicContact CG-CZ 4.47Å; L206-F211 WeakPolarHBondContact O-CD1 3.36Å; L206-L235 WeakPolarHBondContact CA-O 3.49Å; L206-L235 WeakPolarHBondContact CD1-O 3.46Å; L206-R236 VanDerWaalsContact CD1-C 3.48Å; L206-R237 HydrophobicContact CD1-CB 4.5Å; L206-A280 HydrophobicContact CB-CB 4.49Å; L206-A280 HydrophobicContact CD2-CB 3.54Å; L206-F281 HydrophobicContact CB-CE1 3.89Å; L206-F281 HydrophobicContact CB-CZ 4.13Å; L206-F281 HydrophobicContact CD1-CE1 4.33Å
207L97.3Very high96.2Very high39 Ų3933.7 Ų33.720%0.20421%0.209CC..  trans-122.2104171-175.363.3000110D217 P234 L235L207-D217 HydrophobicContact CD2-CB 3.95Å; L207-P234 HydrophobicContact CB-CB 3.63Å; L207-P234 HydrophobicContact CD2-CB 3.6Å; L207-P234 HydrophobicContact CD2-CG 4.47Å; L207-P234 HydrophobicContact CG-CB 4.27Å; L207-L235 PolarHBondContact N-O 3.05Å
208E95.2Very high96.2Very high48 Ų4833.4 Ų33.422%0.22421%0.205CC..  trans-140.2151.3175.2-71.9178.1174.900109.3L206 G210 F211 R237L206-E208 HydrophobicContact CD1-CG 3.75Å; L206-E208 HydrophobicContact CG-CG 4.42Å; E208-G210 PolarHBondContact O-N 2.71Å; E208-G210 VanDerWaalsContact O-N 3.11Å; E208-F211 HydrophobicContact CB-CB 4.37Å; E208-F211 PolarHBondContact O-N 2.59Å; E208-R237 WeakPolarHBondContact OE1-CB 3.41Å; E208-R237 PolarHBondContact OE1-N 3.19Å; E208-R237 IonicContact OE2-CZ 2.87Å; E208-R237 IonicContact OE2-NE 3.95Å; E208-R237 PolarHBondContact OE2-NE 3.28Å; E208-R237 VanDerWaalsContact OE2-NE 3.1Å; E208-R237 IonicContact OE2-NH2 3.56Å; E208-R237 PolarHBondContact OE2-NH2 2.94Å
209P94.8Very high96.2Very high141 Ų14134.7 Ų34.792%0.91622%0.216SC*.THydrogen-bonded Turntrans-52.6121174.4-27.235.5000111.8
210G94Very high96Very high73 Ų7337.4 Ų37.475%0.75323%0.23SC*.THydrogen-bonded Turntrans86.2-2.4179.800000115.4E208E208-G210 PolarHBondContact O-N 2.71Å; E208-G210 VanDerWaalsContact O-N 3.11Å
211F96Very high95.9Very high23 Ų2340.8 Ų40.810%0.10125%0.245CC..SBendtrans-82.6121.7170.7-165.5-99.2000109.9V181 H182 L206 E208 C214 A280V181-F211 HydrophobicContact CG1-CE1 4.4Å; V181-F211 HydrophobicContact CG1-CZ 3.96Å; V181-F211 HydrophobicContact CG2-CZ 4.47Å; H182-F211 AromaticContact CD2-CE1 3.56Å; H182-F211 AromaticContact CD2-CZ 3.66Å; H182-F211 AromaticContact NE2-CE1 3.98Å; H182-F211 AromaticContact NE2-CZ 3.56Å; L206-F211 HydrophobicContact CB-CD1 3.77Å; L206-F211 HydrophobicContact CB-CE1 3.7Å; L206-F211 HydrophobicContact CB-CG 4.39Å; L206-F211 HydrophobicContact CB-CZ 4.26Å; L206-F211 HydrophobicContact CD2-CB 4.47Å; L206-F211 HydrophobicContact CD2-CD1 3.89Å; L206-F211 HydrophobicContact CD2-CD2 3.55Å; L206-F211 HydrophobicContact CD2-CE1 3.98Å; L206-F211 HydrophobicContact CD2-CE2 3.65Å; L206-F211 HydrophobicContact CD2-CG 3.68Å; L206-F211 HydrophobicContact CD2-CZ 3.87Å; L206-F211 HydrophobicContact CG-CB 4.46Å; L206-F211 HydrophobicContact CG-CD1 3.77Å; L206-F211 HydrophobicContact CG-CD2 4.29Å; L206-F211 HydrophobicContact CG-CE1 4.08Å; L206-F211 HydrophobicContact CG-CG 3.89Å; L206-F211 HydrophobicContact CG-CZ 4.47Å; L206-F211 WeakPolarHBondContact O-CD1 3.36Å; E208-F211 HydrophobicContact CB-CB 4.37Å; E208-F211 PolarHBondContact O-N 2.59Å; F211-C214 WeakPolarHBondContact O-CA 3.32Å; F211-C214 PolarHBondContact O-N 3.15Å; F211-C214 PolarHBondContact O-SG 3.31Å; F211-A280 HydrophobicContact CE2-CB 4.16Å; F211-A280 HydrophobicContact CZ-CB 4.04Å
212Y95.5Very high95.7Very high83 Ų8340.9 Ų40.933%0.32525%0.248SC..THydrogen-bonded Turntrans-60.5142-179.3-173.6-91.7000110.7H145 A152 H182H145-Y212 AromaticContact CD2-CE1 3.82Å; H145-Y212 AromaticContact CE1-CE1 3.63Å; H145-Y212 AromaticContact CG-CE1 3.89Å; H145-Y212 AromaticContact ND1-CE1 3.75Å; H145-Y212 AromaticContact NE2-CD1 3.94Å; H145-Y212 AromaticContact NE2-CE1 3.62Å; A152-Y212 WeakPolarHBondContact CB-OH 3.35Å; H182-Y212 PolarHBondContact CD2-O 2.54Å
213P94.9Very high95.5Very high25 Ų2544.6 Ų44.616%0.16227%0.27CS..THydrogen-bonded Turncis-93.318.1-1.333-28.1000113.9H183 D185 S215H183-P213 HydrophobicContact CB-CG 3.97Å; D185-P213 HydrophobicContact CB-CB 4.14Å; D185-P213 HydrophobicContact CB-CG 3.53Å; P213-S215 VanDerWaalsContact C-N 3.26Å; P213-S215 PolarHBondContact O-N 3.11Å
214C93.1Very high95.4Very high82 Ų8247.6 Ų47.655%0.55430%0.302SS*.  trans60.626.7179.6-58.70000115F211F211-C214 WeakPolarHBondContact O-CA 3.32Å; F211-C214 PolarHBondContact O-N 3.15Å; F211-C214 PolarHBondContact O-SG 3.31Å
215S94.7Very high95.2Very high32 Ų3257.8 Ų57.822%0.22434%0.34CS..  trans-131.1175.7176.460.80000110.8H183 D185 P213H183-S215 PolarHBondContact ND1-O 2.98Å; H183-S215 PolarHBondContact ND1-OG 3.15Å; D185-S215 WeakPolarHBondContact CB-OG 3.33Å; P213-S215 VanDerWaalsContact C-N 3.26Å; P213-S215 PolarHBondContact O-N 3.11Å
216G95.8Very high95Very high0 Ų057.9 Ų57.90%034%0.341CS..  trans93.233.6178.800000112.1H183 H205 D220 N232H183-G216 WeakPolarHBondContact CE1-CA 3.38Å; H183-G216 PolarHBondContact CE1-N 2.86Å; H183-G216 VanDerWaalsContact ND1-CA 3.29Å; H183-G216 WeakPolarHBondContact ND1-CA 3.39Å; H183-G216 PolarHBondContact ND1-N 2.89Å; H183-G216 VanDerWaalsContact ND1-N 3.18Å; H205-G216 PolarHBondContact NE2-O 3.33Å; G216-D220 WeakPolarHBondContact CA-OD2 3.42Å; G216-D220 PolarHBondContact N-OD2 2.89Å; G216-N232 WeakPolarHBondContact O-CB 3.32Å
217D96Very high94.8Very high61 Ų6162.5 Ų62.533%0.32636%0.361SS..  trans-62.5157.7170.6-169.2-91000109.8L207 T219 D220 N232L207-D217 HydrophobicContact CD2-CB 3.95Å; D217-T219 PolarHBondContact O-N 3Å; D217-T219 WeakPolarHBondContact OD1-CG2 3.21Å; D217-T219 PolarHBondContact OD1-N 3.19Å; D217-T219 PolarHBondContact OD1-OG1 3.48Å; D217-T219 VanDerWaalsContact OD1-OG1 3.1Å; D217-D220 PolarHBondContact N-OD2 3.25Å; D217-D220 WeakPolarHBondContact O-CB 3.42Å; D217-D220 PolarHBondContact O-N 2.94Å; D217-N232 WeakPolarHBondContact O-CB 3.4Å
218V95.8Very high94.7Very high11 Ų1161.1 Ų61.17%0.06735%0.354CS..THydrogen-bonded Turntrans-58.9-20.717475.50000111.5P234 I369 I372 I373 R376V218-P234 HydrophobicContact CB-CG 3.95Å; V218-I369 HydrophobicContact CB-CD1 4.06Å; V218-I369 HydrophobicContact CG1-CD1 4.14Å; V218-I369 HydrophobicContact CG2-CD1 4.3Å; V218-I369 HydrophobicContact CG2-CG2 4.45Å; V218-I372 HydrophobicContact CG1-CD1 4.03Å; V218-I372 HydrophobicContact CG1-CG2 4.2Å; V218-I372 HydrophobicContact CG2-CB 3.97Å; V218-I372 HydrophobicContact CG2-CG2 3.58Å; V218-I373 HydrophobicContact CG2-CG1 3.94Å; V218-R376 PolarHBondContact O-NH1 3.4Å
219T94.7Very high94.7Very high90 Ų9059.1 Ų59.155%0.55234%0.344SS*.THydrogen-bonded Turntrans-80.3-8.2172.663.20000115.1D217 F221D217-T219 PolarHBondContact O-N 3Å; D217-T219 WeakPolarHBondContact OD1-CG2 3.21Å; D217-T219 PolarHBondContact OD1-N 3.19Å; D217-T219 PolarHBondContact OD1-OG1 3.48Å; D217-T219 VanDerWaalsContact OD1-OG1 3.1Å; T219-F221 WeakPolarHBondContact O-CD1 3.49Å; T219-F221 WeakPolarHBondContact O-CE1 3.37Å; T219-F221 PolarHBondContact O-N 3.02Å
220D94.2Very high94.8Very high59 Ų5952.5 Ų52.532%0.31630%0.301SS..  trans-84.9100.9174.5-61.3-23.4000108.1G216 D217 N232G216-D220 WeakPolarHBondContact CA-OD2 3.42Å; G216-D220 PolarHBondContact N-OD2 2.89Å; D217-D220 PolarHBondContact N-OD2 3.25Å; D217-D220 WeakPolarHBondContact O-CB 3.42Å; D217-D220 PolarHBondContact O-N 2.94Å; D220-N232 PolarHBondContact O-ND2 3.02Å
221F94.3Very high94.9Very high72 Ų7249 Ų4932%0.31627%0.266SS..  trans-129.921.5-172.153.6-108000114.2T219 K227 N228 A230T219-F221 WeakPolarHBondContact O-CD1 3.49Å; T219-F221 WeakPolarHBondContact O-CE1 3.37Å; T219-F221 PolarHBondContact O-N 3.02Å; F221-K227 HydrophobicContact CD2-CG 3.88Å; F221-K227 HydrophobicContact CE2-CD 4.34Å; F221-K227 HydrophobicContact CE2-CG 3.96Å; F221-K227 CarbonylContact O-C 3.54Å; F221-N228 WeakPolarHBondContact O-CA 3.45Å; F221-N228 PolarHBondContact O-N 3.1Å; F221-A230 WeakPolarHBondContact CA-O 3.37Å
222G93.6Very high94.9Very high10 Ų1048 Ų4810%0.10326%0.261CS..  trans77.3174-179.800000113.9
223V94.5Very high95.1Very high77 Ų7744 Ų4447%0.46725%0.246SC..  trans-133.5159.7-168.4-56.70000112.1I194 A195 R225 G226 K227I194-V223 HydrophobicContact CD1-CG1 4.26Å; I194-V223 HydrophobicContact CD1-CG2 4.48Å; I194-V223 HydrophobicContact CG1-CG1 4.43Å; I194-V223 HydrophobicContact CG1-CG2 4.13Å; I194-V223 HydrophobicContact CG2-CG2 4.01Å; I194-V223 PolarHBondContact O-N 3.36Å; A195-V223 WeakPolarHBondContact CA-O 3.17Å; A195-V223 HydrophobicContact CB-CG2 4.23Å; V223-R225 PolarHBondContact O-N 3.37Å; V223-R225 VanDerWaalsContact O-N 3.14Å; V223-G226 CarbonylContact O-C 3.54Å; V223-G226 WeakPolarHBondContact O-CA 3.48Å; V223-G226 PolarHBondContact O-N 3.23Å; V223-K227 PolarHBondContact O-N 2.62Å
224G94.6Very high95.2Very high68 Ų6843 Ų4370%0.70124%0.239SC*.G310 helixtrans53.5-122.5175.700000112.2G226 K227G224-G226 VanDerWaalsContact C-N 3.31Å; G224-K227 WeakPolarHBondContact O-CB 3.48Å; G224-K227 PolarHBondContact O-N 3.45Å
225R93.7Very high95.4Very high216 Ų21639.1 Ų39.182%0.81521%0.212SC*.G310 helixtrans-72.8-22.2177.1-68.2-177.2178.5177.7-0.2113.5A195 A197 V223 K227A195-R225 WeakPolarHBondContact O-CB 3.34Å; A197-R225 WeakPolarHBondContact CB-O 3.4Å; V223-R225 PolarHBondContact O-N 3.37Å; V223-R225 VanDerWaalsContact O-N 3.14Å; R225-K227 VanDerWaalsContact C-N 3.29Å
226G94.3Very high95.6Very high1 Ų142.5 Ų42.51%0.0122%0.22CC..G310 helixtrans-87.16175.400000113.5I194 A195 S196 V223 G224 N228 Y229I194-G226 WeakPolarHBondContact O-CA 3.42Å; A195-G226 VanDerWaalsContact C-N 3.31Å; A195-G226 PolarHBondContact O-N 2.99Å; S196-G226 WeakPolarHBondContact O-CA 3.22Å; V223-G226 CarbonylContact O-C 3.54Å; V223-G226 WeakPolarHBondContact O-CA 3.48Å; V223-G226 PolarHBondContact O-N 3.23Å; G224-G226 VanDerWaalsContact C-N 3.31Å; G226-N228 PolarHBondContact O-N 3.27Å; G226-Y229 WeakPolarHBondContact O-CB 3.32Å; G226-Y229 PolarHBondContact O-N 3.45Å
227K94.5Very high95.7Very high101 Ų10146 Ų4644%0.43923%0.233SC..THydrogen-bonded Turntrans-57.9130174.8-172.8-178178.2-178.60110.6F221 V223 G224 R225 Y229F221-K227 HydrophobicContact CD2-CG 3.88Å; F221-K227 HydrophobicContact CE2-CD 4.34Å; F221-K227 HydrophobicContact CE2-CG 3.96Å; F221-K227 CarbonylContact O-C 3.54Å; V223-K227 PolarHBondContact O-N 2.62Å; G224-K227 WeakPolarHBondContact O-CB 3.48Å; G224-K227 PolarHBondContact O-N 3.45Å; R225-K227 VanDerWaalsContact C-N 3.29Å; K227-Y229 VanDerWaalsContact O-CD2 3.29Å; K227-Y229 WeakPolarHBondContact O-CD2 3.43Å; K227-Y229 PolarHBondContact O-N 3.26Å
228N94.8Very high95.8Very high11 Ų1143 Ų436%0.05922%0.218CC..THydrogen-bonded Turntrans68.26.7-171.4-54.5-48.2000115.7F221 G226 Q379 L380F221-N228 WeakPolarHBondContact O-CA 3.45Å; F221-N228 PolarHBondContact O-N 3.1Å; G226-N228 PolarHBondContact O-N 3.27Å; N228-Q379 PolarHBondContact ND2-OE1 3.13Å; N228-L380 HydrophobicContact CB-CD1 4.49Å; N228-L380 HydrophobicContact CB-CD2 3.67Å; N228-L380 HydrophobicContact CB-CG 4.06Å
229Y95.4Very high95.9Very high5 Ų542.5 Ų42.52%0.0222%0.215CC..  trans-96.5-3.4174.8-67.3-97.8000113.5A197 M200 T201 G226 K227 F259 L380 F384A197-Y229 HydrophobicContact CB-CD2 4.24Å; A197-Y229 HydrophobicContact CB-CE1 4.06Å; A197-Y229 HydrophobicContact CB-CE2 3.75Å; A197-Y229 VanDerWaalsContact O-CE1 3.25Å; A197-Y229 WeakPolarHBondContact O-CE1 3.43Å; M200-Y229 CarbonylContact C-O 3.52Å; M200-Y229 WeakPolarHBondContact CA-O 2.98Å; M200-Y229 HydrophobicContact CB-CD1 4.45Å; M200-Y229 HydrophobicContact CE-CD1 3.84Å; M200-Y229 HydrophobicContact CE-CE1 4.41Å; M200-Y229 HydrophobicContact CE-CG 4.44Å; M200-Y229 WeakPolarHBondContact CG-O 3.32Å; T201-Y229 PolarHBondContact N-O 2.86Å; G226-Y229 WeakPolarHBondContact O-CB 3.32Å; G226-Y229 PolarHBondContact O-N 3.45Å; K227-Y229 VanDerWaalsContact O-CD2 3.29Å; K227-Y229 WeakPolarHBondContact O-CD2 3.43Å; K227-Y229 PolarHBondContact O-N 3.26Å; Y229-F259 AromaticContact CD1-CD2 3.74Å; Y229-F259 HydrophobicContact CD1-CD2 3.74Å; Y229-F259 AromaticContact CD1-CE2 3.65Å; Y229-F259 HydrophobicContact CD1-CE2 3.65Å; Y229-F259 AromaticContact CE1-CD2 3.65Å; Y229-F259 HydrophobicContact CE1-CD2 3.65Å; Y229-F259 AromaticContact CE1-CE2 3.74Å; Y229-F259 HydrophobicContact CE1-CE2 3.74Å; Y229-L380 HydrophobicContact CD1-CD2 4.42Å; Y229-L380 HydrophobicContact CD2-CD2 3.77Å; Y229-L380 HydrophobicContact CE1-CD2 4.09Å; Y229-L380 HydrophobicContact CE2-CD2 3.39Å; Y229-L380 HydrophobicContact CG-CD2 4.27Å; Y229-F384 VanDerWaalsContact OH-CE2 3.3Å; Y229-F384 WeakPolarHBondContact OH-CE2 3.38Å
230A95.7Very high96.1Very high2 Ų242.6 Ų42.62%0.01721%0.207CC..EExtended strand (participates in β ladder)trans-100.4124.2162.300000109.5E190 F221E190-A230 HydrophobicContact CG-CB 3.96Å; E190-A230 WeakPolarHBondContact OE2-CB 3.35Å; F221-A230 WeakPolarHBondContact CA-O 3.37Å
231V96.4Very high96.2Very high1 Ų140.4 Ų40.41%0.00620%0.196CC..EExtended strand (participates in β ladder)trans-120.295.6-176.9-177.20000109.5M200 T201 V202 S203 L255 I373 F377M200-V231 HydrophobicContact CG-CG2 4.48Å; M200-V231 HydrophobicContact SD-CG2 4.44Å; T201-V231 PolarHBondContact O-N 3.14Å; V202-V231 VanDerWaalsContact CA-O 3.28Å; V202-V231 WeakPolarHBondContact CA-O 3.32Å; V202-V231 HydrophobicContact CB-CB 4.42Å; V202-V231 HydrophobicContact CG1-CB 4.21Å; V202-V231 HydrophobicContact CG1-CG1 4.2Å; V202-V231 HydrophobicContact CG2-CB 4.12Å; S203-V231 PolarHBondContact N-O 3.12Å; V231-L255 HydrophobicContact CG1-CD2 4.48Å; V231-L255 HydrophobicContact CG2-CD2 3.97Å; V231-I373 HydrophobicContact CG1-CG2 3.72Å; V231-F377 HydrophobicContact CG1-CZ 4.45Å; V231-F377 HydrophobicContact CG2-CE1 4.03Å
232N97.3Very high96.4Very high0 Ų043.5 Ų43.50%021%0.211CC..EExtended strand (participates in β ladder)trans-94.4131.9177.4-69.6-50.5000112.4H183 E190 H205 G216 D217 D220 P234H183-N232 PolarHBondContact CD2-OD1 2.87Å; H183-N232 PolarHBondContact NE2-OD1 2.94Å; E190-N232 PolarHBondContact OE2-ND2 3.4Å; E190-N232 PolarHBondContact OE2-OD1 3.05Å; H205-N232 PolarHBondContact CE1-OD1 2.85Å; G216-N232 WeakPolarHBondContact O-CB 3.32Å; D217-N232 WeakPolarHBondContact O-CB 3.4Å; D220-N232 PolarHBondContact O-ND2 3.02Å; N232-P234 WeakPolarHBondContact O-CD 3.46Å
233V97.8Very high96.6Very high1 Ų144.7 Ų44.71%0.00621%0.214CC..EExtended strand (participates in β ladder)trans-11881179.3-165.40000108S203 F204 H205 L235 I247 I251 I369 I373S203-V233 WeakPolarHBondContact O-CB 3.43Å; S203-V233 PolarHBondContact O-N 2.92Å; F204-V233 HydrophobicContact CD1-CB 3.84Å; F204-V233 HydrophobicContact CD1-CG1 3.92Å; F204-V233 HydrophobicContact CD1-CG2 3.86Å; F204-V233 HydrophobicContact CE1-CB 4.29Å; F204-V233 HydrophobicContact CE1-CG1 4.28Å; F204-V233 HydrophobicContact CE1-CG2 3.85Å; F204-V233 HydrophobicContact CG-CB 4.28Å; F204-V233 HydrophobicContact CG-CG2 4.31Å; F204-V233 HydrophobicContact CZ-CG2 4.28Å; H205-V233 PolarHBondContact N-O 2.92Å; V233-L235 HydrophobicContact CG1-CD2 4.33Å; V233-L235 HydrophobicContact CG1-CG 4.45Å; V233-L235 WeakPolarHBondContact O-CG 3.23Å; V233-L235 PolarHBondContact O-N 3.25Å; V233-I247 HydrophobicContact CG1-CG2 3.84Å; V233-I251 HydrophobicContact CG1-CD1 4.13Å; V233-I251 HydrophobicContact CG2-CD1 3.64Å; V233-I369 HydrophobicContact CG1-CG2 4.1Å; V233-I373 HydrophobicContact CB-CD1 4.32Å; V233-I373 HydrophobicContact CG1-CD1 4.21Å; V233-I373 HydrophobicContact CG2-CD1 3.83Å
234P97.9Very high96.8Very high2 Ų241.1 Ų41.11%0.01319%0.192CC..EExtended strand (participates in β ladder)trans-71.4122.7-179.128.8-36.2000110.8L207 V218 N232 Y365 I369L207-P234 HydrophobicContact CB-CB 3.63Å; L207-P234 HydrophobicContact CD2-CB 3.6Å; L207-P234 HydrophobicContact CD2-CG 4.47Å; L207-P234 HydrophobicContact CG-CB 4.27Å; V218-P234 HydrophobicContact CB-CG 3.95Å; N232-P234 WeakPolarHBondContact O-CD 3.46Å; P234-Y365 PolarHBondContact O-OH 2.86Å; P234-I369 HydrophobicContact CG-CD1 3.9Å
235L98.4Very high96.9Very high1 Ų139.2 Ų39.21%0.00517%0.166CC..EExtended strand (participates in β ladder)trans-115.8165.7-176.8-60.9157.5000109.9F204 H205 L206 L207 V233 L239 I247 F281 L366F204-L235 HydrophobicContact CB-CD1 4.08Å; H205-L235 WeakPolarHBondContact O-CB 3.36Å; H205-L235 PolarHBondContact O-N 2.88Å; L206-L235 WeakPolarHBondContact CA-O 3.49Å; L206-L235 WeakPolarHBondContact CD1-O 3.46Å; L207-L235 PolarHBondContact N-O 3.05Å; V233-L235 HydrophobicContact CG1-CD2 4.33Å; V233-L235 HydrophobicContact CG1-CG 4.45Å; V233-L235 WeakPolarHBondContact O-CG 3.23Å; V233-L235 PolarHBondContact O-N 3.25Å; L235-L239 HydrophobicContact CB-CD2 4.27Å; L235-L239 HydrophobicContact CD1-CD2 3.59Å; L235-L239 HydrophobicContact CD2-CD1 4.37Å; L235-L239 HydrophobicContact CD2-CD2 4Å; L235-L239 HydrophobicContact CG-CD2 4.12Å; L235-I247 HydrophobicContact CD2-CD1 3.65Å; L235-F281 HydrophobicContact CB-CE1 3.83Å; L235-F281 HydrophobicContact CB-CZ 3.7Å; L235-F281 HydrophobicContact CD1-CE2 4.24Å; L235-F281 HydrophobicContact CD1-CZ 3.82Å; L235-F281 HydrophobicContact CG-CZ 4.4Å; L235-L366 HydrophobicContact CD2-CD2 3.82Å
236R98Very high97.1Very high104 Ų10433.9 Ų33.939%0.39215%0.15SC..  trans-111.5167179.7-61.8179.5176.6-173.6-2.7111.4L206 A360 N361 Y365L206-R236 VanDerWaalsContact CD1-C 3.48Å; R236-A360 HydrophobicContact CB-CB 3.8Å; R236-A360 WeakPolarHBondContact CD-O 3.19Å; R236-N361 PolarHBondContact N-OD1 3.02Å; R236-N361 PolarHBondContact O-ND2 3.37Å; R236-Y365 HydrophobicContact CG-CD1 4.49Å; R236-Y365 HydrophobicContact CG-CE1 3.93Å
237R97.8Very high97.2Very high72 Ų7234 Ų3427%0.27215%0.151SC..THydrogen-bonded Turntrans-56.6144.4-178.7-160167.2-60.7-89.4-1.9113.2L206 E208 N278 Q279 A280 L357 A360L206-R237 HydrophobicContact CD1-CB 4.5Å; E208-R237 WeakPolarHBondContact OE1-CB 3.41Å; E208-R237 PolarHBondContact OE1-N 3.19Å; E208-R237 IonicContact OE2-CZ 2.87Å; E208-R237 IonicContact OE2-NE 3.95Å; E208-R237 PolarHBondContact OE2-NE 3.28Å; E208-R237 VanDerWaalsContact OE2-NE 3.1Å; E208-R237 IonicContact OE2-NH2 3.56Å; E208-R237 PolarHBondContact OE2-NH2 2.94Å; R237-N278 PolarHBondContact NH1-O 2.72Å; R237-Q279 WeakPolarHBondContact CG-O 3.34Å; R237-Q279 PolarHBondContact NH1-O 3.05Å; R237-A280 CarbonylContact C-O 3.33Å; R237-A280 VanDerWaalsContact CA-O 3.24Å; R237-A280 WeakPolarHBondContact CA-O 3.43Å; R237-A280 VanDerWaalsContact CG-O 3.27Å; R237-A280 WeakPolarHBondContact CG-O 3.28Å; R237-L357 HydrophobicContact CG-CD1 4.28Å; R237-L357 HydrophobicContact CG-CD2 3.98Å; R237-L357 HydrophobicContact CG-CG 4.37Å; R237-A360 PolarHBondContact O-N 3.15Å
238G98Very high97.3Very high0 Ų029.3 Ų29.30%013%0.13CC..THydrogen-bonded Turntrans76.519.6173.700000116A280 P358 N359G238-A280 PolarHBondContact N-O 3.21Å; G238-P358 WeakPolarHBondContact CA-O 3.36Å; G238-N359 VanDerWaalsContact O-CB 3.24Å; G238-N359 WeakPolarHBondContact O-CB 3.49Å; G238-N359 PolarHBondContact O-OD1 3.5Å
239L98.2Very high97.4Very high0 Ų031.8 Ų31.80%014%0.143CC..  trans-52.7138.5171.2-171.870.6000111.2L235 Q243 F244 I247 F281 N282 N361L235-L239 HydrophobicContact CB-CD2 4.27Å; L235-L239 HydrophobicContact CD1-CD2 3.59Å; L235-L239 HydrophobicContact CD2-CD1 4.37Å; L235-L239 HydrophobicContact CD2-CD2 4Å; L235-L239 HydrophobicContact CG-CD2 4.12Å; L239-Q243 HydrophobicContact CD1-CB 3.66Å; L239-F244 HydrophobicContact CD2-CB 4.21Å; L239-F244 HydrophobicContact CD2-CD2 3.65Å; L239-F244 HydrophobicContact CD2-CG 4.43Å; L239-I247 HydrophobicContact CD1-CD1 4.3Å; L239-F281 HydrophobicContact CB-CB 4.31Å; L239-F281 HydrophobicContact CB-CD1 3.71Å; L239-F281 HydrophobicContact CB-CE1 4.17Å; L239-F281 HydrophobicContact CB-CG 4.01Å; L239-F281 HydrophobicContact CD2-CD2 4.48Å; L239-F281 HydrophobicContact CD2-CE1 4.41Å; L239-F281 HydrophobicContact CD2-CE2 4.35Å; L239-F281 HydrophobicContact CD2-CZ 4.33Å; L239-N282 CarbonylContact O-C 3.52Å; L239-N282 WeakPolarHBondContact O-CA 3.47Å; L239-N282 PolarHBondContact O-N 3.11Å; L239-N361 HydrophobicContact CD1-CB 3.97Å; L239-N361 PolarHBondContact N-ND2 2.71Å
240K97.9Very high97.4Very high91 Ų9134.4 Ų34.440%0.39616%0.156SC..  trans-111.5163.7-177.9-63.8-172.4176.1-171.90112E242 Q243 F244K240-E242 VanDerWaalsContact C-N 3.35Å; K240-E242 PolarHBondContact O-N 2.92Å; K240-Q243 PolarHBondContact O-N 3.06Å; K240-F244 PolarHBondContact O-N 2.92Å
241D98.2Very high97.3Very high14 Ų1434.3 Ų34.38%0.07516%0.155CC..Hα-helixtrans-53.4-46.2-175.6-67.6-34.5000113.2Q243 F244 I245 L283 T284 S287D241-Q243 VanDerWaalsContact C-N 3.3Å; D241-Q243 PolarHBondContact O-N 3.28Å; D241-F244 PolarHBondContact O-N 3.15Å; D241-I245 WeakPolarHBondContact O-CB 3.47Å; D241-I245 WeakPolarHBondContact O-CD1 3.18Å; D241-I245 VanDerWaalsContact O-CG1 3.22Å; D241-I245 WeakPolarHBondContact O-CG1 3.32Å; D241-I245 PolarHBondContact O-N 3.47Å; D241-L283 WeakPolarHBondContact OD1-CA 3.33Å; D241-T284 PolarHBondContact OD1-N 3.2Å; D241-T284 WeakPolarHBondContact OD2-CB 3.27Å; D241-T284 WeakPolarHBondContact OD2-CG2 3.24Å; D241-T284 PolarHBondContact OD2-N 3.08Å; D241-T284 PolarHBondContact OD2-OG1 3.44Å; D241-S287 WeakPolarHBondContact OD1-CB 3.48Å; D241-S287 PolarHBondContact OD1-OG 3.41Å
242E97.4Very high97.2Very high137 Ų13734.7 Ų34.764%0.6416%0.157SC*.Hα-helixtrans-61.6-41.4-176.7-6077.7-165.800111.7K240 E246K240-E242 VanDerWaalsContact C-N 3.35Å; K240-E242 PolarHBondContact O-N 2.92Å; E242-E246 WeakPolarHBondContact O-CB 3.42Å; E242-E246 PolarHBondContact O-N 3.02Å
243Q97.7Very high97Very high34 Ų3438 Ų3816%0.15918%0.178CC..Hα-helixtrans-71.9-42.6179.2-68.3-179.7-4700111.6L239 K240 D241 I245 E246 I247 N359 N361 L366L239-Q243 HydrophobicContact CD1-CB 3.66Å; K240-Q243 PolarHBondContact O-N 3.06Å; D241-Q243 VanDerWaalsContact C-N 3.3Å; D241-Q243 PolarHBondContact O-N 3.28Å; Q243-I245 VanDerWaalsContact C-N 3.31Å; Q243-I245 PolarHBondContact O-N 3.24Å; Q243-E246 PolarHBondContact O-N 3.1Å; Q243-I247 VanDerWaalsContact O-CD1 3.22Å; Q243-I247 WeakPolarHBondContact O-CD1 3.45Å; Q243-I247 WeakPolarHBondContact O-CG1 3.48Å; Q243-I247 PolarHBondContact O-N 3.31Å; Q243-N359 PolarHBondContact OE1-ND2 3.48Å; Q243-N361 PolarHBondContact NE2-O 2.96Å; Q243-L366 HydrophobicContact CB-CD1 3.93Å; Q243-L366 HydrophobicContact CG-CD1 3.99Å
244F98.2Very high96.8Very high2 Ų242.4 Ų42.41%0.00920%0.195CC..Hα-helixtrans-58.6-47.2177.1-169.1-84.2000110.9L179 F204 L239 K240 D241 I247 L248 L283 S291L179-F244 HydrophobicContact CD2-CE1 4.49Å; L179-F244 HydrophobicContact CD2-CZ 4.06Å; F204-F244 HydrophobicContact CB-CE2 3.98Å; F204-F244 HydrophobicContact CB-CZ 4.18Å; F204-F244 HydrophobicContact CG-CZ 4.42Å; L239-F244 HydrophobicContact CD2-CB 4.21Å; L239-F244 HydrophobicContact CD2-CD2 3.65Å; L239-F244 HydrophobicContact CD2-CG 4.43Å; K240-F244 PolarHBondContact O-N 2.92Å; D241-F244 PolarHBondContact O-N 3.15Å; F244-I247 PolarHBondContact O-N 3.38Å; F244-L248 PolarHBondContact O-N 2.86Å; F244-L283 HydrophobicContact CB-CD2 3.89Å; F244-L283 HydrophobicContact CD2-CD1 3.88Å; F244-L283 HydrophobicContact CD2-CD2 4.34Å; F244-L283 HydrophobicContact CE2-CD1 4.14Å; F244-L283 HydrophobicContact CG-CD1 4.29Å; F244-L283 HydrophobicContact CG-CD2 4.28Å; F244-S291 WeakPolarHBondContact CE1-OG 3.35Å
245I98.1Very high96.6Very high28 Ų2842.4 Ų42.414%0.14420%0.195CC..Hα-helixtrans-63.6-43.2178.1-66.6164.3000111D241 Q243 I247 L248 D249 I286 V290D241-I245 WeakPolarHBondContact O-CB 3.47Å; D241-I245 WeakPolarHBondContact O-CD1 3.18Å; D241-I245 VanDerWaalsContact O-CG1 3.22Å; D241-I245 WeakPolarHBondContact O-CG1 3.32Å; D241-I245 PolarHBondContact O-N 3.47Å; Q243-I245 VanDerWaalsContact C-N 3.31Å; Q243-I245 PolarHBondContact O-N 3.24Å; I245-I247 VanDerWaalsContact C-N 3.34Å; I245-I247 PolarHBondContact O-N 3Å; I245-L248 PolarHBondContact O-N 2.85Å; I245-D249 WeakPolarHBondContact O-CB 3.41Å; I245-D249 PolarHBondContact O-N 3.45Å; I245-I286 HydrophobicContact CD1-CG2 4.21Å; I245-V290 HydrophobicContact CD1-CB 3.97Å; I245-V290 HydrophobicContact CD1-CG1 4.04Å; I245-V290 HydrophobicContact CD1-CG2 4.02Å; I245-V290 HydrophobicContact CG1-CB 4.13Å; I245-V290 HydrophobicContact CG1-CG1 3.96Å; I245-V290 HydrophobicContact CG2-CG1 3.85Å
246E97.3Very high96.3Very high105 Ų10546.3 Ų46.349%0.49121%0.209SC..Hα-helixtrans-59.8-43.3177.6-174.2-171.316200112E242 Q243 Q250E242-E246 WeakPolarHBondContact O-CB 3.42Å; E242-E246 PolarHBondContact O-N 3.02Å; Q243-E246 PolarHBondContact O-N 3.1Å; E246-Q250 WeakPolarHBondContact O-CG 3.26Å; E246-Q250 PolarHBondContact O-N 2.83Å; E246-Q250 PolarHBondContact OE1-NE2 2.76Å
247I97.3Very high96Very high4 Ų446.8 Ų46.82%0.02122%0.224CC..Hα-helixtrans-65.3-46.3178.6-61.5156000109.9F204 V233 L235 L239 Q243 F244 I245 Q250 I251 L366 I370F204-I247 HydrophobicContact CD1-CG2 4.33Å; F204-I247 HydrophobicContact CE1-CG2 4Å; V233-I247 HydrophobicContact CG1-CG2 3.84Å; L235-I247 HydrophobicContact CD2-CD1 3.65Å; L239-I247 HydrophobicContact CD1-CD1 4.3Å; Q243-I247 VanDerWaalsContact O-CD1 3.22Å; Q243-I247 WeakPolarHBondContact O-CD1 3.45Å; Q243-I247 WeakPolarHBondContact O-CG1 3.48Å; Q243-I247 PolarHBondContact O-N 3.31Å; F244-I247 PolarHBondContact O-N 3.38Å; I245-I247 VanDerWaalsContact C-N 3.34Å; I245-I247 PolarHBondContact O-N 3Å; I247-Q250 PolarHBondContact O-N 2.84Å; I247-I251 HydrophobicContact CG2-CD1 3.74Å; I247-I251 WeakPolarHBondContact O-CG1 3.37Å; I247-I251 PolarHBondContact O-N 3.5Å; I247-L366 HydrophobicContact CD1-CD1 4.07Å; I247-L366 HydrophobicContact CD1-CD2 3.65Å; I247-L366 HydrophobicContact CD1-CG 4.37Å; I247-L366 HydrophobicContact CG1-CD2 4.41Å; I247-I370 HydrophobicContact CB-CD1 4.44Å; I247-I370 HydrophobicContact CG1-CD1 4.11Å; I247-I370 HydrophobicContact CG2-CD1 4.37Å; I247-I370 HydrophobicContact CG2-CG1 4.3Å
248L96.4Very high95.7Very high1 Ų144.3 Ų44.31%0.00522%0.217CC..Hα-helixtrans-60.6-47.8178.1-175.977.9000111.8F204 F244 I245 Q250 I251 L252 S291 R294F204-L248 HydrophobicContact CE1-CD1 4.41Å; F204-L248 HydrophobicContact CE2-CD1 4.14Å; F204-L248 HydrophobicContact CZ-CD1 3.75Å; F244-L248 PolarHBondContact O-N 2.86Å; I245-L248 PolarHBondContact O-N 2.85Å; L248-Q250 PolarHBondContact O-N 3.27Å; L248-Q250 VanDerWaalsContact O-N 3.17Å; L248-I251 PolarHBondContact O-N 3.17Å; L248-I251 VanDerWaalsContact O-N 3.09Å; L248-L252 HydrophobicContact CD1-CB 4.26Å; L248-L252 HydrophobicContact CG-CB 4.32Å; L248-L252 WeakPolarHBondContact O-CB 3.42Å; L248-L252 PolarHBondContact O-N 3.22Å; L248-S291 VanDerWaalsContact CD2-CA 3.42Å; L248-S291 WeakPolarHBondContact CD2-OG 3.25Å; L248-R294 HydrophobicContact CD2-CB 4.35Å; L248-R294 HydrophobicContact CD2-CG 4.44Å
249D96Very high95.6Very high63 Ų6344.5 Ų44.534%0.33722%0.217SC..Hα-helixtrans-62.1-23.2-180-82.5-19.1000111.6I245 P253 R294I245-D249 WeakPolarHBondContact O-CB 3.41Å; I245-D249 PolarHBondContact O-N 3.45Å; D249-P253 VanDerWaalsContact O-CD 3.22Å; D249-P253 WeakPolarHBondContact O-CD 3.49Å; D249-P253 WeakPolarHBondContact O-CG 3.18Å; D249-R294 WeakPolarHBondContact OD1-CD 3.35Å; D249-R294 IonicContact OD1-CZ 3.53Å; D249-R294 IonicContact OD1-NE 2.71Å; D249-R294 PolarHBondContact OD1-NE 3.37Å; D249-R294 IonicContact OD2-NE 2.77Å; D249-R294 IonicContact OD2-NH2 3.96Å
250Q95.3Very high95.4Very high60 Ų6047.6 Ų47.628%0.2823%0.234SC..Hα-helixtrans-85.6-30.2173.9-73.1-174.269.300114.3E246 I247 L248 R254 I370E246-Q250 WeakPolarHBondContact O-CG 3.26Å; E246-Q250 PolarHBondContact O-N 2.83Å; E246-Q250 PolarHBondContact OE1-NE2 2.76Å; I247-Q250 PolarHBondContact O-N 2.84Å; L248-Q250 PolarHBondContact O-N 3.27Å; L248-Q250 VanDerWaalsContact O-N 3.17Å; Q250-R254 VanDerWaalsContact O-CD 3.3Å; Q250-R254 WeakPolarHBondContact O-CD 3.28Å; Q250-R254 PolarHBondContact O-NE 3.31Å; Q250-I370 HydrophobicContact CB-CD1 4.44Å; Q250-I370 HydrophobicContact CB-CG2 4.25Å
251I94.8Very high95.4Very high1 Ų143.3 Ų43.31%0.00522%0.216CC..Hα-helixtrans-92.3-49.9-175.3-67.6177.4000111.2F204 V233 I247 L248 R254 L255 I373F204-I251 HydrophobicContact CE1-CD1 4.04Å; F204-I251 HydrophobicContact CZ-CD1 4.44Å; F204-I251 HydrophobicContact CZ-CG2 4.42Å; V233-I251 HydrophobicContact CG1-CD1 4.13Å; V233-I251 HydrophobicContact CG2-CD1 3.64Å; I247-I251 HydrophobicContact CG2-CD1 3.74Å; I247-I251 WeakPolarHBondContact O-CG1 3.37Å; I247-I251 PolarHBondContact O-N 3.5Å; L248-I251 PolarHBondContact O-N 3.17Å; L248-I251 VanDerWaalsContact O-N 3.09Å; I251-R254 WeakPolarHBondContact O-CB 3.08Å; I251-R254 PolarHBondContact O-N 2.84Å; I251-L255 HydrophobicContact CG2-CD1 3.63Å; I251-L255 HydrophobicContact CG2-CD2 4.34Å; I251-L255 HydrophobicContact CG2-CG 3.85Å; I251-L255 WeakPolarHBondContact O-CG 3.25Å; I251-L255 PolarHBondContact O-N 3.36Å; I251-I373 HydrophobicContact CD1-CD1 3.89Å
252L94.2Very high95.4Very high9 Ų945.6 Ų45.65%0.04723%0.226CC..Hα-helixtrans-57.8-44.9-169.8-175.167.9000114.1L248 R254 L255 R256 R294 I295 L298L248-L252 HydrophobicContact CD1-CB 4.26Å; L248-L252 HydrophobicContact CG-CB 4.32Å; L248-L252 WeakPolarHBondContact O-CB 3.42Å; L248-L252 PolarHBondContact O-N 3.22Å; L252-R254 VanDerWaalsContact C-N 3.25Å; L252-R254 PolarHBondContact O-N 3.41Å; L252-L255 PolarHBondContact O-N 2.97Å; L252-R256 PolarHBondContact O-N 2.96Å; L252-R256 VanDerWaalsContact O-N 3.12Å; L252-R294 HydrophobicContact CD2-CB 3.75Å; L252-I295 HydrophobicContact CD1-CG1 4.29Å; L252-I295 HydrophobicContact CD2-CG1 3.85Å; L252-L298 HydrophobicContact CD1-CD1 4.1Å; L252-L298 HydrophobicContact CG-CD1 4.34Å
253P92.6Very high95.4Very high69 Ų6939.1 Ų39.145%0.44820%0.195SC..Hα-helixtrans-61.5-35.6177.2-24.135.9000112.6D249 R256 T257D249-P253 VanDerWaalsContact O-CD 3.22Å; D249-P253 WeakPolarHBondContact O-CD 3.49Å; D249-P253 WeakPolarHBondContact O-CG 3.18Å; P253-R256 PolarHBondContact O-N 3.11Å; P253-T257 PolarHBondContact O-N 3.47Å; P253-T257 VanDerWaalsContact O-N 3.15Å; P253-T257 PolarHBondContact O-OG1 2.99Å
254R93.3Very high95.5Very high94 Ų9437.5 Ų37.536%0.35519%0.188SC..Hα-helixtrans-70.1-41.9179.8-62.6177.8176.4157.6-1.9111.2Q250 I251 L252 R256 T257 V258 F377Q250-R254 VanDerWaalsContact O-CD 3.3Å; Q250-R254 WeakPolarHBondContact O-CD 3.28Å; Q250-R254 PolarHBondContact O-NE 3.31Å; I251-R254 WeakPolarHBondContact O-CB 3.08Å; I251-R254 PolarHBondContact O-N 2.84Å; L252-R254 VanDerWaalsContact C-N 3.25Å; L252-R254 PolarHBondContact O-N 3.41Å; R254-R256 VanDerWaalsContact C-N 3.29Å; R254-R256 PolarHBondContact O-N 3.05Å; R254-T257 WeakPolarHBondContact O-CB 3.39Å; R254-T257 PolarHBondContact O-N 2.91Å; R254-T257 VanDerWaalsContact O-N 3.09Å; R254-V258 WeakPolarHBondContact O-CG2 3.31Å; R254-V258 PolarHBondContact O-N 3.34Å; R254-F377 HydrophobicContact CB-CD2 3.55Å; R254-F377 HydrophobicContact CB-CE2 3.46Å; R254-F377 VanDerWaalsContact CB-CE2 3.46Å; R254-F377 HydrophobicContact CG-CD2 4.3Å; R254-F377 HydrophobicContact CG-CE2 4.32Å
255L93.3Very high95.5Very high1 Ų137.4 Ų37.41%0.00519%0.188CC..Hα-helixtrans-56.6-45.3174-63172.2000111M200 V202 V231 I251 L252 T257 V258 F259 F377M200-L255 HydrophobicContact SD-CD2 3.62Å; V202-L255 HydrophobicContact CB-CD1 4.35Å; V202-L255 HydrophobicContact CG1-CD1 3.96Å; V202-L255 HydrophobicContact CG2-CD1 3.6Å; V202-L255 HydrophobicContact CG2-CD2 4.08Å; V202-L255 HydrophobicContact CG2-CG 4.49Å; V231-L255 HydrophobicContact CG1-CD2 4.48Å; V231-L255 HydrophobicContact CG2-CD2 3.97Å; I251-L255 HydrophobicContact CG2-CD1 3.63Å; I251-L255 HydrophobicContact CG2-CD2 4.34Å; I251-L255 HydrophobicContact CG2-CG 3.85Å; I251-L255 WeakPolarHBondContact O-CG 3.25Å; I251-L255 PolarHBondContact O-N 3.36Å; L252-L255 PolarHBondContact O-N 2.97Å; L255-T257 VanDerWaalsContact C-N 3.3Å; L255-T257 PolarHBondContact O-N 2.93Å; L255-V258 PolarHBondContact O-N 3.47Å; L255-F259 VanDerWaalsContact O-CB 3.27Å; L255-F259 WeakPolarHBondContact O-CB 3.41Å; L255-F259 PolarHBondContact O-N 3.38Å; L255-F377 HydrophobicContact CD2-CE1 3.91Å; L255-F377 HydrophobicContact CD2-CZ 3.62Å; L255-F377 HydrophobicContact CG-CZ 4.33Å
256R91.7Very high95.5Very high83 Ų8336.1 Ų36.131%0.31318%0.181SC..Hα-helixtrans-56.9-44.4175.3175.463.3-170.2134.221.7111.6L252 P253 R254 D260 P261 L298L252-R256 PolarHBondContact O-N 2.96Å; L252-R256 VanDerWaalsContact O-N 3.12Å; P253-R256 PolarHBondContact O-N 3.11Å; R254-R256 VanDerWaalsContact C-N 3.29Å; R254-R256 PolarHBondContact O-N 3.05Å; R256-D260 IonicContact CZ-OD1 3.77Å; R256-D260 IonicContact NH1-OD1 2.98Å; R256-D260 PolarHBondContact NH1-OD1 3.04Å; R256-D260 IonicContact NH2-OD1 2.62Å; R256-D260 PolarHBondContact NH2-OD1 2.95Å; R256-D260 WeakPolarHBondContact O-CA 3.17Å; R256-D260 PolarHBondContact O-N 3.19Å; R256-D260 VanDerWaalsContact O-N 3.14Å; R256-P261 PolarHBondContact NH1-O 3.45Å; R256-L298 HydrophobicContact CB-CD2 4.25Å; R256-L298 HydrophobicContact CG-CD2 4.16Å
257T91.9Very high95.6Very high115 Ų11531.1 Ų31.171%0.70616%0.157SC*.Hα-helixtrans-67.2-45.6-179.6-58.60000112.9P253 R254 L255P253-T257 PolarHBondContact O-N 3.47Å; P253-T257 VanDerWaalsContact O-N 3.15Å; P253-T257 PolarHBondContact O-OG1 2.99Å; R254-T257 WeakPolarHBondContact O-CB 3.39Å; R254-T257 PolarHBondContact O-N 2.91Å; R254-T257 VanDerWaalsContact O-N 3.09Å; L255-T257 VanDerWaalsContact C-N 3.3Å; L255-T257 PolarHBondContact O-N 2.93Å
258V93Very high95.7Very high19 Ų1930.9 Ų30.912%0.11516%0.157CC..Hα-helixtrans-88.5-24.7-170.4-57.60000114.3R254 L255 F377 L380 V381R254-V258 WeakPolarHBondContact O-CG2 3.31Å; R254-V258 PolarHBondContact O-N 3.34Å; L255-V258 PolarHBondContact O-N 3.47Å; V258-F377 HydrophobicContact CG1-CB 3.91Å; V258-F377 HydrophobicContact CG1-CG 4.49Å; V258-F377 HydrophobicContact CG2-CB 4.39Å; V258-F377 HydrophobicContact CG2-CD1 4.17Å; V258-F377 HydrophobicContact CG2-CG 4.23Å; V258-L380 HydrophobicContact CB-CB 4.2Å; V258-L380 HydrophobicContact CB-CD1 4.26Å; V258-L380 HydrophobicContact CG2-CD1 3.7Å; V258-V381 HydrophobicContact CG1-CG2 4.03Å
259F95.1Very high95.7Very high4 Ų430.9 Ų30.92%0.01816%0.156CC..Hα-helixtrans-104.1-26-178.6-173.5-119000113.2R173 I174 L175 A197 M200 Y229 L255 P261R173-F259 HydrophobicContact CB-CE1 3.95Å; R173-F259 HydrophobicContact CB-CE2 4.35Å; R173-F259 HydrophobicContact CB-CZ 3.75Å; R173-F259 WeakPolarHBondContact CD-O 3.42Å; R173-F259 HydrophobicContact CG-CE2 4.32Å; R173-F259 HydrophobicContact CG-CZ 4.18Å; R173-F259 PolarHBondContact NE-O 3.21Å; I174-F259 VanDerWaalsContact O-CE1 3.23Å; I174-F259 WeakPolarHBondContact O-CE1 3.49Å; I174-F259 WeakPolarHBondContact O-CZ 3.38Å; L175-F259 HydrophobicContact CB-CD1 4.33Å; L175-F259 HydrophobicContact CB-CE1 4.27Å; L175-F259 HydrophobicContact CD1-CD1 4.45Å; A197-F259 WeakPolarHBondContact O-CE2 3.25Å; M200-F259 HydrophobicContact CB-CD1 3.78Å; M200-F259 HydrophobicContact CB-CD2 3.8Å; M200-F259 HydrophobicContact CB-CE1 3.68Å; M200-F259 HydrophobicContact CB-CE2 3.69Å; M200-F259 HydrophobicContact CB-CG 3.85Å; M200-F259 HydrophobicContact CB-CZ 3.62Å; M200-F259 HydrophobicContact CE-CB 3.68Å; M200-F259 HydrophobicContact CE-CD2 3.71Å; M200-F259 HydrophobicContact CE-CG 3.81Å; M200-F259 HydrophobicContact CG-CG 4.46Å; M200-F259 HydrophobicContact SD-CB 3.67Å; M200-F259 HydrophobicContact SD-CD1 4.21Å; M200-F259 HydrophobicContact SD-CD2 4.19Å; M200-F259 HydrophobicContact SD-CG 3.77Å; Y229-F259 AromaticContact CD1-CD2 3.74Å; Y229-F259 HydrophobicContact CD1-CD2 3.74Å; Y229-F259 AromaticContact CD1-CE2 3.65Å; Y229-F259 HydrophobicContact CD1-CE2 3.65Å; Y229-F259 AromaticContact CE1-CD2 3.65Å; Y229-F259 HydrophobicContact CE1-CD2 3.65Å; Y229-F259 AromaticContact CE1-CE2 3.74Å; Y229-F259 HydrophobicContact CE1-CE2 3.74Å; L255-F259 VanDerWaalsContact O-CB 3.27Å; L255-F259 WeakPolarHBondContact O-CB 3.41Å; L255-F259 PolarHBondContact O-N 3.38Å; F259-P261 HydrophobicContact CD1-CB 3.8Å; F259-P261 HydrophobicContact CD1-CG 4.18Å; F259-P261 HydrophobicContact CE1-CB 3.98Å
260D94.5Very high95.9Very high65 Ų6527.9 Ų27.935%0.34814%0.141SC..  trans43.361.5-175.5-175.636.8000112.5R173 R256R173-D260 VanDerWaalsContact CZ-O 3.26Å; R173-D260 IonicContact CZ-OD2 3.92Å; R173-D260 PolarHBondContact NE-O 2.67Å; R173-D260 PolarHBondContact NH2-O 2.96Å; R173-D260 IonicContact NH2-OD2 3.63Å; R173-D260 PolarHBondContact NH2-OD2 3.27Å; R256-D260 IonicContact CZ-OD1 3.77Å; R256-D260 IonicContact NH1-OD1 2.98Å; R256-D260 PolarHBondContact NH1-OD1 3.04Å; R256-D260 IonicContact NH2-OD1 2.62Å; R256-D260 PolarHBondContact NH2-OD1 2.95Å; R256-D260 WeakPolarHBondContact O-CA 3.17Å; R256-D260 PolarHBondContact O-N 3.19Å; R256-D260 VanDerWaalsContact O-N 3.14Å
261P97.1Very high96Very high2 Ų225 Ų251%0.01313%0.127CC..  trans-60.7157.4-178.122.3-31.2000112.3L175 R256 F259 M300L175-P261 HydrophobicContact CB-CB 3.73Å; L175-P261 HydrophobicContact CB-CG 4.05Å; L175-P261 HydrophobicContact CD2-CG 4.24Å; R256-P261 PolarHBondContact NH1-O 3.45Å; F259-P261 HydrophobicContact CD1-CB 3.8Å; F259-P261 HydrophobicContact CD1-CG 4.18Å; F259-P261 HydrophobicContact CE1-CB 3.98Å; P261-M300 HydrophobicContact CB-CE 4.37Å; P261-M300 HydrophobicContact CB-SD 4.11Å; P261-M300 HydrophobicContact CG-CE 3.64Å; P261-M300 HydrophobicContact CG-SD 3.84Å
262H98Very high96.2Very high62 Ų6225 Ų2529%0.28713%0.127SC..SBendtrans-108.6-21.4175-60.3163000113Y171 K172 R173 P301Y171-H262 HydrophobicContact CD1-CB 3.91Å; Y171-H262 HydrophobicContact CG-CB 4.37Å; K172-H262 PolarHBondContact N-ND1 3.09Å; R173-H262 PolarHBondContact NH2-NE2 2.85Å; R173-H262 PolarHBondContact O-N 3.05Å; H262-P301 WeakPolarHBondContact O-CD 3.5Å
263A98.7Very high96.4Very high0 Ų024.8 Ų24.80%013%0.126CC..EExtended strand (participates in β ladder)trans-150.6159.2170.900000109.1L167 Y171 R173 I174 L175 P301L167-A263 HydrophobicContact CD1-CB 4.48Å; Y171-A263 HydrophobicContact CD1-CB 4.27Å; Y171-A263 HydrophobicContact CD2-CB 3.71Å; Y171-A263 HydrophobicContact CE2-CB 4.19Å; Y171-A263 HydrophobicContact CG-CB 3.76Å; R173-A263 PolarHBondContact O-N 2.86Å; I174-A263 WeakPolarHBondContact CA-O 3.34Å; I174-A263 HydrophobicContact CD1-CB 3.88Å; L175-A263 PolarHBondContact N-O 2.87Å; A263-P301 CarbonylContact C-O 3.53Å; A263-P301 WeakPolarHBondContact CA-O 3.49Å; A263-P301 HydrophobicContact CB-CB 4.12Å
264I98.7Very high96.6Very high1 Ų122.3 Ų22.31%0.00511%0.11CC..EExtended strand (participates in β ladder)trans-124.8139.4-178.9-44.8176.8000109L175 V177 V266 I295 L298 M300 P301 C302 L303L175-I264 HydrophobicContact CB-CG2 4.43Å; L175-I264 HydrophobicContact CD2-CG2 4.48Å; L175-I264 CarbonylContact O-C 3.54Å; L175-I264 VanDerWaalsContact O-CA 3.26Å; L175-I264 WeakPolarHBondContact O-CA 3.34Å; V177-I264 HydrophobicContact CG2-CG2 4.27Å; I264-V266 HydrophobicContact CG2-CG2 3.8Å; I264-I295 HydrophobicContact CD1-CG2 3.64Å; I264-I295 HydrophobicContact CG2-CG2 4.03Å; I264-L298 HydrophobicContact CD1-CB 4.36Å; I264-L298 HydrophobicContact CD1-CD1 3.86Å; I264-M300 HydrophobicContact CD1-CB 4.39Å; I264-M300 HydrophobicContact CD1-CE 3.44Å; I264-M300 VanDerWaalsContact CD1-CE 3.44Å; I264-M300 HydrophobicContact CG1-CB 4.25Å; I264-M300 HydrophobicContact CG1-CE 3.68Å; I264-M300 HydrophobicContact CG1-SD 4.49Å; I264-P301 PolarHBondContact N-O 2.77Å; I264-C302 CarbonylContact O-C 3.37Å; I264-C302 WeakPolarHBondContact O-CA 3.35Å; I264-L303 PolarHBondContact O-N 3.38Å
265V98.8Very high96.7Very high0 Ų020.5 Ų20.50%012%0.12CC..EExtended strand (participates in β ladder)trans-113.8128.1163.1-179.50000107.2I164 L167 I174 L175 Y176 V177 L303 L305I164-V265 HydrophobicContact CG1-CB 4.39Å; I164-V265 HydrophobicContact CG1-CG2 3.86Å; L167-V265 HydrophobicContact CD1-CG2 3.42Å; L167-V265 VanDerWaalsContact CD1-CG2 3.42Å; I174-V265 HydrophobicContact CG2-CG2 4.09Å; L175-V265 PolarHBondContact O-N 2.83Å; Y176-V265 CarbonylContact C-O 3.59Å; Y176-V265 WeakPolarHBondContact CA-O 3.36Å; Y176-V265 HydrophobicContact CD2-CB 3.96Å; Y176-V265 HydrophobicContact CD2-CG1 3.84Å; Y176-V265 HydrophobicContact CE2-CG1 4.09Å; V177-V265 PolarHBondContact N-O 3.1Å; V265-L303 CarbonylContact C-O 3.38Å; V265-L303 WeakPolarHBondContact CA-O 3.16Å; V265-L303 HydrophobicContact CG1-CB 4.4Å; V265-L303 HydrophobicContact CG1-CD2 4.13Å; V265-L303 HydrophobicContact CG1-CG 4.26Å; V265-L303 HydrophobicContact CG2-CB 4.17Å; V265-L303 HydrophobicContact CG2-CD2 4.21Å; V265-L305 HydrophobicContact CG1-CD1 3.8Å; V265-L305 HydrophobicContact CG1-CG 4.33Å
266V98.7Very high96.9Very high0 Ų020.8 Ų20.80%012%0.121CC..EExtended strand (participates in β ladder)trans-117.7117.5178.7-166.10000108.4V177 I264 L268 I295 L303 L304 L305V177-V266 HydrophobicContact CB-CG1 4.44Å; V177-V266 CarbonylContact O-C 3.58Å; V177-V266 VanDerWaalsContact O-CA 3.29Å; V177-V266 WeakPolarHBondContact O-CA 3.46Å; I264-V266 HydrophobicContact CG2-CG2 3.8Å; V266-L268 HydrophobicContact CG1-CD2 3.94Å; V266-L268 HydrophobicContact CG1-CG 3.9Å; V266-I295 HydrophobicContact CG1-CD1 3.96Å; V266-I295 HydrophobicContact CG2-CD1 4.07Å; V266-I295 HydrophobicContact CG2-CG2 3.79Å; V266-L303 PolarHBondContact N-O 3Å; V266-L304 HydrophobicContact CB-CD2 3.89Å; V266-L304 HydrophobicContact CG2-CD2 3.92Å; V266-L305 PolarHBondContact O-N 2.82Å
267Q98.4Very high97.2Very high0 Ų020.5 Ų20.50%013%0.13CC..EExtended strand (participates in β ladder)trans-85.6125.4166.6-163.7-80.615.600107.2G142 Y176 V177 D178 L179 D180 G306G142-Q267 PolarHBondContact O-NE2 2.87Å; Y176-Q267 HydrophobicContact CE2-CB 4.1Å; Y176-Q267 WeakPolarHBondContact OH-CB 3.47Å; V177-Q267 PolarHBondContact O-N 3.13Å; D178-Q267 PolarHBondContact OD1-OE1 2.82Å; L179-Q267 PolarHBondContact N-O 2.87Å; L179-Q267 VanDerWaalsContact N-O 3.1Å; D180-Q267 PolarHBondContact OD2-NE2 3.36Å; Q267-G306 WeakPolarHBondContact CG-O 3.42Å
268L98.5Very high97.3Very high0 Ų017.1 Ų17.10%011%0.108CC..  trans-118.956.4-177.2-68.2162.8000109.5L179 V266 V270 L304 L305 G306 W319 L322L179-L268 HydrophobicContact CD1-CD2 3.85Å; V266-L268 HydrophobicContact CG1-CD2 3.94Å; V266-L268 HydrophobicContact CG1-CG 3.9Å; L268-V270 WeakPolarHBondContact O-CG1 3.48Å; L268-V270 PolarHBondContact O-N 2.92Å; L268-L304 HydrophobicContact CD1-CB 4.21Å; L268-L304 HydrophobicContact CD1-CD2 4.29Å; L268-L305 WeakPolarHBondContact CB-O 3.22Å; L268-L305 PolarHBondContact N-O 3.05Å; L268-G306 CarbonylContact C-O 3.57Å; L268-G306 PolarHBondContact N-O 3.34Å; L268-G306 VanDerWaalsContact N-O 3.13Å; L268-W319 HydrophobicContact CB-CH2 4.06Å; L268-W319 HydrophobicContact CB-CZ2 3.62Å; L268-W319 HydrophobicContact CD1-CH2 4Å; L268-W319 HydrophobicContact CD1-CZ2 4.39Å; L268-W319 PolarHBondContact O-NE1 3.1Å; L268-L322 HydrophobicContact CB-CD1 4.33Å; L268-L322 HydrophobicContact CD1-CD1 4.25Å; L268-L322 HydrophobicContact CD1-CD2 4.3Å; L268-L322 HydrophobicContact CD2-CD2 4.33Å
269G98.2Very high97.4Very high0 Ų022.4 Ų22.40%013%0.131CC..  trans-62.3124.4165.100000109.2D180 Y288 G306 G308D180-G269 WeakPolarHBondContact OD2-CA 3.29Å; G269-Y288 WeakPolarHBondContact O-CE1 3.48Å; G269-G306 PolarHBondContact N-O 3.49Å; G269-G308 WeakPolarHBondContact CA-O 3.22Å
270V98.5Very high97.5Very high1 Ų122.2 Ų22.21%0.00613%0.131CC..  trans-108.920.9-171.9-62.60000112.5L268 G272 L273 Y288 G308 F315 C318 L322L268-V270 WeakPolarHBondContact O-CG1 3.48Å; L268-V270 PolarHBondContact O-N 2.92Å; V270-G272 PolarHBondContact O-N 3.49Å; V270-L273 HydrophobicContact CB-CD1 3.75Å; V270-L273 HydrophobicContact CB-CG 4.11Å; V270-L273 HydrophobicContact CG2-CD1 4.11Å; V270-L273 WeakPolarHBondContact O-CB 3.4Å; V270-L273 WeakPolarHBondContact O-CD1 3.34Å; V270-L273 WeakPolarHBondContact O-CG 3.44Å; V270-L273 PolarHBondContact O-N 3.24Å; V270-L273 VanDerWaalsContact O-N 3.11Å; V270-Y288 HydrophobicContact CG1-CD1 4.19Å; V270-Y288 HydrophobicContact CG1-CE1 4.14Å; V270-Y288 HydrophobicContact CG1-CG 4.41Å; V270-G308 PolarHBondContact N-O 2.99Å; V270-F315 HydrophobicContact CG2-CB 4.19Å; V270-F315 HydrophobicContact CG2-CD2 3.29Å; V270-F315 HydrophobicContact CG2-CE2 3.89Å; V270-F315 HydrophobicContact CG2-CG 3.98Å; V270-C318 HydrophobicContact CG1-CB 4.25Å; V270-L322 HydrophobicContact CG1-CD1 4.35Å
271D98.2Very high97.7Very high0 Ų019.3 Ų19.30%012%0.115CC..THydrogen-bonded Turntrans-75.7-4.917449.14.8000114.4V181 H182 D276 G308 Y310V181-D271 HydrophobicContact CG1-CB 4.12Å; V181-D271 VanDerWaalsContact CG1-CG 3.43Å; V181-D271 WeakPolarHBondContact CG1-OD1 2.96Å; V181-D271 PolarHBondContact N-OD1 3.31Å; H182-D271 IonicContact CE1-OD2 2.68Å; H182-D271 PolarHBondContact CE1-OD2 3.35Å; H182-D271 IonicContact ND1-OD2 3.97Å; H182-D271 PolarHBondContact ND1-OD2 3.48Å; H182-D271 VanDerWaalsContact ND1-OD2 3.12Å; D271-D276 WeakPolarHBondContact O-CB 3.35Å; D271-G308 WeakPolarHBondContact OD2-CA 3.29Å; D271-Y310 HydrophobicContact CB-CD2 3.92Å; D271-Y310 HydrophobicContact CB-CE2 3.83Å; D271-Y310 WeakPolarHBondContact OD2-CE2 3.39Å
272G98.3Very high97.8Very high0 Ų019.6 Ų19.60%012%0.116CC..THydrogen-bonded Turntrans-74.6-8.5161.600000113.7V270 F281 L283 Y288V270-G272 PolarHBondContact O-N 3.49Å; G272-F281 CarbonylContact O-C 3.19Å; G272-F281 WeakPolarHBondContact O-CB 3.25Å; G272-L283 WeakPolarHBondContact O-CB 3.12Å; G272-L283 PolarHBondContact O-N 2.95Å; G272-Y288 VanDerWaalsContact CA-OH 3.26Å; G272-Y288 WeakPolarHBondContact CA-OH 3.2Å; G272-Y288 PolarHBondContact N-OH 3.47Å
273L98.5Very high97.8Very high4 Ų416.7 Ų16.72%0.02110%0.103CC..BIsolated β-bridgetrans-63.4141.7177.8-73.5172.8000111.5V270 G275 D276 L283 T284 P285 Y288 N314 C318 I352V270-L273 HydrophobicContact CB-CD1 3.75Å; V270-L273 HydrophobicContact CB-CG 4.11Å; V270-L273 HydrophobicContact CG2-CD1 4.11Å; V270-L273 WeakPolarHBondContact O-CB 3.4Å; V270-L273 WeakPolarHBondContact O-CD1 3.34Å; V270-L273 WeakPolarHBondContact O-CG 3.44Å; V270-L273 PolarHBondContact O-N 3.24Å; V270-L273 VanDerWaalsContact O-N 3.11Å; L273-G275 PolarHBondContact O-N 2.96Å; L273-D276 VanDerWaalsContact O-CB 3.22Å; L273-D276 WeakPolarHBondContact O-CB 3.42Å; L273-D276 PolarHBondContact O-N 2.68Å; L273-D276 VanDerWaalsContact O-N 3.08Å; L273-L283 CarbonylContact C-O 3.59Å; L273-L283 WeakPolarHBondContact CA-O 3.5Å; L273-T284 VanDerWaalsContact CD2-C 3.42Å; L273-P285 HydrophobicContact CD2-CG 4.18Å; L273-Y288 HydrophobicContact CD2-CD2 4.04Å; L273-Y288 HydrophobicContact CD2-CE2 3.66Å; L273-Y288 HydrophobicContact CG-CE2 3.85Å; L273-N314 HydrophobicContact CD1-CB 4.14Å; L273-C318 HydrophobicContact CD1-CB 3.64Å; L273-I352 HydrophobicContact CD1-CD1 4.23Å
274T97.9Very high97.8Very high18 Ų1817.2 Ų17.211%0.1111%0.106CC..THydrogen-bonded Turntrans-54.1138.9166.3-1760000111.2D276 N282 L283 N314 I352 Q353 G355T274-D276 VanDerWaalsContact C-N 3.27Å; T274-D276 PolarHBondContact O-N 3.02Å; T274-N282 WeakPolarHBondContact CB-OD1 3.29Å; T274-N282 PolarHBondContact OG1-OD1 3.31Å; T274-L283 WeakPolarHBondContact CG2-O 3.41Å; T274-L283 PolarHBondContact N-O 3Å; T274-N314 PolarHBondContact O-ND2 3.3Å; T274-I352 HydrophobicContact CG2-CG2 3.46Å; T274-I352 VanDerWaalsContact CG2-CG2 3.46Å; T274-Q353 WeakPolarHBondContact CG2-O 3.4Å; T274-G355 WeakPolarHBondContact OG1-CA 3.33Å; T274-G355 PolarHBondContact OG1-N 2.95Å; T274-G355 VanDerWaalsContact OG1-N 3.11Å
275G96Very high97.8Very high56 Ų5617.3 Ų17.358%0.57711%0.107SC*.THydrogen-bonded Turntrans80.9-1.6-175.300000114.8L273L273-G275 PolarHBondContact O-N 2.96Å
276D97.6Very high97.7Very high6 Ų622 Ų223%0.03213%0.131CC..  trans-67.6139.3168.2-165.6-81.7000110.9D271 L273 T274 N278 Q279 Y310 Q311D271-D276 WeakPolarHBondContact O-CB 3.35Å; L273-D276 VanDerWaalsContact O-CB 3.22Å; L273-D276 WeakPolarHBondContact O-CB 3.42Å; L273-D276 PolarHBondContact O-N 2.68Å; L273-D276 VanDerWaalsContact O-N 3.08Å; T274-D276 VanDerWaalsContact C-N 3.27Å; T274-D276 PolarHBondContact O-N 3.02Å; D276-N278 PolarHBondContact O-N 3.32Å; D276-N278 VanDerWaalsContact O-N 3.08Å; D276-N278 WeakPolarHBondContact OD1-CB 3.44Å; D276-N278 PolarHBondContact OD1-N 3.37Å; D276-N278 PolarHBondContact OD1-ND2 3.12Å; D276-Q279 PolarHBondContact O-N 2.88Å; D276-Y310 PolarHBondContact OD2-N 3.33Å; D276-Q311 PolarHBondContact OD2-N 2.93Å
277P96.2Very high97.7Very high77 Ų7722 Ų2250%0.513%0.131SC..THydrogen-bonded Turntrans-51.3-28.2176.9-29.835.3000115.5Q279P277-Q279 PolarHBondContact O-N 3.24Å
278N95.1Very high97.7Very high45 Ų4522 Ų2224%0.24113%0.131CC..THydrogen-bonded Turntrans-66.2-22.9178.8-71.7-31.6000113.5H182 R237 D276 A280 Y310H182-N278 PolarHBondContact CE1-ND2 3.39Å; R237-N278 PolarHBondContact NH1-O 2.72Å; D276-N278 PolarHBondContact O-N 3.32Å; D276-N278 VanDerWaalsContact O-N 3.08Å; D276-N278 WeakPolarHBondContact OD1-CB 3.44Å; D276-N278 PolarHBondContact OD1-N 3.37Å; D276-N278 PolarHBondContact OD1-ND2 3.12Å; N278-A280 HydrophobicContact CB-CB 4.3Å; N278-A280 PolarHBondContact O-N 2.82Å; N278-Y310 VanDerWaalsContact ND2-CD2 3.34Å; N278-Y310 WeakPolarHBondContact ND2-CD2 3.35Å; N278-Y310 WeakPolarHBondContact ND2-CE2 3.42Å
279Q95.7Very high97.7Very high129 Ų12922.8 Ų22.860%0.60314%0.136SC*.  trans47.937.8180-64175.563.900112.7R237 D276 P277 L357R237-Q279 WeakPolarHBondContact CG-O 3.34Å; R237-Q279 PolarHBondContact NH1-O 3.05Å; D276-Q279 PolarHBondContact O-N 2.88Å; P277-Q279 PolarHBondContact O-N 3.24Å; Q279-L357 WeakPolarHBondContact O-CD2 3.34Å
280A97.3Very high97.7Very high1 Ų124.1 Ų24.11%0.00814%0.144CC..  trans-89.8-63.3-17100000110.7V181 L206 F211 R237 G238 N278V181-A280 HydrophobicContact CB-CB 4.3Å; V181-A280 HydrophobicContact CG1-CB 4.19Å; V181-A280 HydrophobicContact CG2-CB 3.29Å; L206-A280 HydrophobicContact CB-CB 4.49Å; L206-A280 HydrophobicContact CD2-CB 3.54Å; F211-A280 HydrophobicContact CE2-CB 4.16Å; F211-A280 HydrophobicContact CZ-CB 4.04Å; R237-A280 CarbonylContact C-O 3.33Å; R237-A280 VanDerWaalsContact CA-O 3.24Å; R237-A280 WeakPolarHBondContact CA-O 3.43Å; R237-A280 VanDerWaalsContact CG-O 3.27Å; R237-A280 WeakPolarHBondContact CG-O 3.28Å; G238-A280 PolarHBondContact N-O 3.21Å; N278-A280 HydrophobicContact CB-CB 4.3Å; N278-A280 PolarHBondContact O-N 2.82Å
281F98.1Very high97.7Very high4 Ų424 Ų242%0.01814%0.144CC..  trans-106177.7172.7-58.3-29.1000112.1V181 L206 L235 L239 G272 L283V181-F281 HydrophobicContact CB-CD2 4.49Å; V181-F281 HydrophobicContact CB-CE2 4.44Å; V181-F281 HydrophobicContact CG2-CD1 4.24Å; V181-F281 HydrophobicContact CG2-CD2 3.69Å; V181-F281 HydrophobicContact CG2-CE1 4.18Å; V181-F281 HydrophobicContact CG2-CE2 3.63Å; V181-F281 HydrophobicContact CG2-CG 3.99Å; V181-F281 HydrophobicContact CG2-CZ 3.88Å; L206-F281 HydrophobicContact CB-CE1 3.89Å; L206-F281 HydrophobicContact CB-CZ 4.13Å; L206-F281 HydrophobicContact CD1-CE1 4.33Å; L235-F281 HydrophobicContact CB-CE1 3.83Å; L235-F281 HydrophobicContact CB-CZ 3.7Å; L235-F281 HydrophobicContact CD1-CE2 4.24Å; L235-F281 HydrophobicContact CD1-CZ 3.82Å; L235-F281 HydrophobicContact CG-CZ 4.4Å; L239-F281 HydrophobicContact CB-CB 4.31Å; L239-F281 HydrophobicContact CB-CD1 3.71Å; L239-F281 HydrophobicContact CB-CE1 4.17Å; L239-F281 HydrophobicContact CB-CG 4.01Å; L239-F281 HydrophobicContact CD2-CD2 4.48Å; L239-F281 HydrophobicContact CD2-CE1 4.41Å; L239-F281 HydrophobicContact CD2-CE2 4.35Å; L239-F281 HydrophobicContact CD2-CZ 4.33Å; G272-F281 CarbonylContact O-C 3.19Å; G272-F281 WeakPolarHBondContact O-CB 3.25Å; F281-L283 HydrophobicContact CB-CD1 4.28Å; F281-L283 HydrophobicContact CB-CG 3.86Å; F281-L283 HydrophobicContact CD2-CD1 3.92Å; F281-L283 HydrophobicContact CD2-CG 4.38Å
282N98Very high97.7Very high7 Ų724 Ų244%0.03714%0.144CC..  trans-125.545177.6-167.815.3000109.7L239 T274 G355 L357L239-N282 CarbonylContact O-C 3.52Å; L239-N282 WeakPolarHBondContact O-CA 3.47Å; L239-N282 PolarHBondContact O-N 3.11Å; T274-N282 WeakPolarHBondContact CB-OD1 3.29Å; T274-N282 PolarHBondContact OG1-OD1 3.31Å; N282-G355 PolarHBondContact ND2-O 3.4Å; N282-G355 WeakPolarHBondContact OD1-CA 3.43Å; N282-G355 PolarHBondContact OD1-N 3.03Å; N282-L357 HydrophobicContact CB-CB 4.34Å
283L98.6Very high97.6Very high1 Ų126 Ų261%0.00515%0.153CC..BIsolated β-bridgetrans-83.7155.3-177.9-59-178.4000111D241 F244 G272 L273 T274 F281 S287 Y288D241-L283 WeakPolarHBondContact OD1-CA 3.33Å; F244-L283 HydrophobicContact CB-CD2 3.89Å; F244-L283 HydrophobicContact CD2-CD1 3.88Å; F244-L283 HydrophobicContact CD2-CD2 4.34Å; F244-L283 HydrophobicContact CE2-CD1 4.14Å; F244-L283 HydrophobicContact CG-CD1 4.29Å; F244-L283 HydrophobicContact CG-CD2 4.28Å; G272-L283 WeakPolarHBondContact O-CB 3.12Å; G272-L283 PolarHBondContact O-N 2.95Å; L273-L283 CarbonylContact C-O 3.59Å; L273-L283 WeakPolarHBondContact CA-O 3.5Å; T274-L283 WeakPolarHBondContact CG2-O 3.41Å; T274-L283 PolarHBondContact N-O 3Å; F281-L283 HydrophobicContact CB-CD1 4.28Å; F281-L283 HydrophobicContact CB-CG 3.86Å; F281-L283 HydrophobicContact CD2-CD1 3.92Å; F281-L283 HydrophobicContact CD2-CG 4.38Å; L283-S287 WeakPolarHBondContact CB-OG 3.46Å; L283-Y288 HydrophobicContact CB-CE2 4.12Å; L283-Y288 HydrophobicContact CD1-CE2 4.19Å
284T98.5Very high97.6Very high11 Ų1129.7 Ų29.77%0.06717%0.167CC..  trans-113.2172.8165.778.90000109.3D241 L273 I286 S287 I352D241-T284 PolarHBondContact OD1-N 3.2Å; D241-T284 WeakPolarHBondContact OD2-CB 3.27Å; D241-T284 WeakPolarHBondContact OD2-CG2 3.24Å; D241-T284 PolarHBondContact OD2-N 3.08Å; D241-T284 PolarHBondContact OD2-OG1 3.44Å; L273-T284 VanDerWaalsContact CD2-C 3.42Å; T284-I286 PolarHBondContact O-N 3.41Å; T284-I286 WeakPolarHBondContact OG1-CB 3.45Å; T284-I286 WeakPolarHBondContact OG1-CG1 3.45Å; T284-I286 PolarHBondContact OG1-N 2.95Å; T284-S287 PolarHBondContact O-N 2.79Å; T284-S287 PolarHBondContact O-OG 2.75Å; T284-I352 WeakPolarHBondContact CG2-O 3.27Å
285P98.3Very high97.5Very high3 Ų328.9 Ų28.92%0.01916%0.162CC..Hα-helixtrans-54.5-18.1174.3-29.538.9000114.2L273 Y288 C289 C318 I352L273-P285 HydrophobicContact CD2-CG 4.18Å; P285-Y288 PolarHBondContact O-N 3.36Å; P285-C289 WeakPolarHBondContact O-CB 3.36Å; P285-C289 PolarHBondContact O-N 3.36Å; P285-C289 PolarHBondContact O-SG 2.91Å; P285-C318 HydrophobicContact CB-CB 4.35Å; P285-C318 HydrophobicContact CG-CB 4.05Å; P285-I352 HydrophobicContact CG-CB 4.41Å; P285-I352 HydrophobicContact CG-CD1 3.7Å; P285-I352 HydrophobicContact CG-CG1 4.08Å
286I98.2Very high97.6Very high98 Ų9827 Ų2750%0.50314%0.138SC..Hα-helixtrans-57.7-49.2177.2-63.6173.3000111.1I245 T284 Y288 C289 V290I245-I286 HydrophobicContact CD1-CG2 4.21Å; T284-I286 PolarHBondContact O-N 3.41Å; T284-I286 WeakPolarHBondContact OG1-CB 3.45Å; T284-I286 WeakPolarHBondContact OG1-CG1 3.45Å; T284-I286 PolarHBondContact OG1-N 2.95Å; I286-Y288 PolarHBondContact O-N 3.08Å; I286-C289 PolarHBondContact O-N 3.45Å; I286-V290 HydrophobicContact CG2-CG2 4.17Å; I286-V290 WeakPolarHBondContact O-CB 3.34Å; I286-V290 VanDerWaalsContact O-CG2 3.27Å; I286-V290 WeakPolarHBondContact O-CG2 3.25Å; I286-V290 PolarHBondContact O-N 3.46Å
287S98.1Very high97.5Very high0 Ų028.8 Ų28.80%015%0.154CC..Hα-helixtrans-61.1-46.5-178.353.40000111.6D241 L283 T284 S291D241-S287 WeakPolarHBondContact OD1-CB 3.48Å; D241-S287 PolarHBondContact OD1-OG 3.41Å; L283-S287 WeakPolarHBondContact CB-OG 3.46Å; T284-S287 PolarHBondContact O-N 2.79Å; T284-S287 PolarHBondContact O-OG 2.75Å; S287-S291 VanDerWaalsContact O-CB 3.27Å; S287-S291 WeakPolarHBondContact O-CB 3.42Å; S287-S291 PolarHBondContact O-N 3.48Å; S287-S291 PolarHBondContact O-OG 3.05Å
288Y98.6Very high97.4Very high1 Ų127.1 Ų27.10%0.00414%0.141CC..Hα-helixtrans-64.1-44.4176.9-61.2-84.7000112.7L179 G269 V270 G272 L273 L283 P285 I286 S291 L292L179-Y288 HydrophobicContact CB-CE1 4.39Å; G269-Y288 WeakPolarHBondContact O-CE1 3.48Å; V270-Y288 HydrophobicContact CG1-CD1 4.19Å; V270-Y288 HydrophobicContact CG1-CE1 4.14Å; V270-Y288 HydrophobicContact CG1-CG 4.41Å; G272-Y288 VanDerWaalsContact CA-OH 3.26Å; G272-Y288 WeakPolarHBondContact CA-OH 3.2Å; G272-Y288 PolarHBondContact N-OH 3.47Å; L273-Y288 HydrophobicContact CD2-CD2 4.04Å; L273-Y288 HydrophobicContact CD2-CE2 3.66Å; L273-Y288 HydrophobicContact CG-CE2 3.85Å; L283-Y288 HydrophobicContact CB-CE2 4.12Å; L283-Y288 HydrophobicContact CD1-CE2 4.19Å; P285-Y288 PolarHBondContact O-N 3.36Å; I286-Y288 PolarHBondContact O-N 3.08Å; Y288-S291 PolarHBondContact O-N 2.77Å; Y288-L292 WeakPolarHBondContact O-CB 3.4Å; Y288-L292 PolarHBondContact O-N 2.88Å
289C98.3Very high97.3Very high16 Ų1632 Ų3211%0.10817%0.167CC..Hα-helixtrans-68-41.9-179.6-67.10000112.1P285 I286 S291 L292 Q293 T325P285-C289 WeakPolarHBondContact O-CB 3.36Å; P285-C289 PolarHBondContact O-N 3.36Å; P285-C289 PolarHBondContact O-SG 2.91Å; I286-C289 PolarHBondContact O-N 3.45Å; C289-S291 VanDerWaalsContact C-N 3.32Å; C289-L292 PolarHBondContact O-N 3.23Å; C289-Q293 WeakPolarHBondContact O-CB 3.39Å; C289-Q293 PolarHBondContact O-N 2.96Å; C289-T325 HydrophobicContact CB-CG2 4.42Å
290V98.2Very high97.3Very high28 Ų2827 Ų2717%0.1714%0.144CC..Hα-helixtrans-63.3-42.8174172.40000110I245 I286 L292 Q293 R294I245-V290 HydrophobicContact CD1-CB 3.97Å; I245-V290 HydrophobicContact CD1-CG1 4.04Å; I245-V290 HydrophobicContact CD1-CG2 4.02Å; I245-V290 HydrophobicContact CG1-CB 4.13Å; I245-V290 HydrophobicContact CG1-CG1 3.96Å; I245-V290 HydrophobicContact CG2-CG1 3.85Å; I286-V290 HydrophobicContact CG2-CG2 4.17Å; I286-V290 WeakPolarHBondContact O-CB 3.34Å; I286-V290 VanDerWaalsContact O-CG2 3.27Å; I286-V290 WeakPolarHBondContact O-CG2 3.25Å; I286-V290 PolarHBondContact O-N 3.46Å; V290-L292 PolarHBondContact O-N 3.1Å; V290-Q293 WeakPolarHBondContact O-CB 3.15Å; V290-Q293 PolarHBondContact O-N 3.23Å; V290-R294 HydrophobicContact CG1-CG 4.42Å; V290-R294 VanDerWaalsContact O-CG 3.31Å; V290-R294 WeakPolarHBondContact O-CG 3.41Å; V290-R294 PolarHBondContact O-N 2.97Å
291S98.1Very high97.4Very high0 Ų028.4 Ų28.40%015%0.153CC..Hα-helixtrans-59.5-49177.2-57.40000111.8F244 L248 S287 Y288 C289 Q293 R294 I295F244-S291 WeakPolarHBondContact CE1-OG 3.35Å; L248-S291 VanDerWaalsContact CD2-CA 3.42Å; L248-S291 WeakPolarHBondContact CD2-OG 3.25Å; S287-S291 VanDerWaalsContact O-CB 3.27Å; S287-S291 WeakPolarHBondContact O-CB 3.42Å; S287-S291 PolarHBondContact O-N 3.48Å; S287-S291 PolarHBondContact O-OG 3.05Å; Y288-S291 PolarHBondContact O-N 2.77Å; C289-S291 VanDerWaalsContact C-N 3.32Å; S291-Q293 VanDerWaalsContact C-N 3.33Å; S291-Q293 PolarHBondContact O-N 3.46Å; S291-R294 PolarHBondContact O-N 2.83Å; S291-I295 WeakPolarHBondContact O-CG1 3.27Å; S291-I295 PolarHBondContact O-N 2.76Å
292L98.1Very high97.4Very high0 Ų028.3 Ų28.30%015%0.152CC..Hα-helixtrans-59.1-43.917617960000111.5Y288 C289 V290 R294 I295 L296 L304 L322 T325 A326Y288-L292 WeakPolarHBondContact O-CB 3.4Å; Y288-L292 PolarHBondContact O-N 2.88Å; C289-L292 PolarHBondContact O-N 3.23Å; V290-L292 PolarHBondContact O-N 3.1Å; L292-R294 VanDerWaalsContact C-N 3.34Å; L292-R294 PolarHBondContact O-N 3.43Å; L292-I295 PolarHBondContact O-N 2.9Å; L292-L296 HydrophobicContact CD1-CD1 3.85Å; L292-L296 HydrophobicContact CD1-CD2 4.29Å; L292-L296 HydrophobicContact CD1-CG 3.78Å; L292-L296 HydrophobicContact CD2-CD1 4.49Å; L292-L296 HydrophobicContact CG-CD1 3.87Å; L292-L296 HydrophobicContact CG-CG 4.2Å; L292-L296 WeakPolarHBondContact O-CB 3.35Å; L292-L296 VanDerWaalsContact O-CG 3.29Å; L292-L296 WeakPolarHBondContact O-CG 3.19Å; L292-L296 PolarHBondContact O-N 3.39Å; L292-L304 HydrophobicContact CD1-CD1 3.69Å; L292-L304 HydrophobicContact CD1-CD2 3.56Å; L292-L304 HydrophobicContact CD1-CG 4.3Å; L292-L304 HydrophobicContact CD2-CD1 4.17Å; L292-L322 HydrophobicContact CB-CD2 4.09Å; L292-L322 HydrophobicContact CD2-CB 4.28Å; L292-L322 HydrophobicContact CD2-CD2 3.72Å; L292-L322 WeakPolarHBondContact CD2-O 3.22Å; L292-T325 HydrophobicContact CD2-CG2 4.32Å; L292-T325 HydrophobicContact CG-CG2 4.48Å; L292-A326 HydrophobicContact CD2-CB 4.31Å
293Q97.3Very high97.5Very high40 Ų4028 Ų2819%0.18715%0.15CC..Hα-helixtrans-59.6-43.2176.5-175.8-179.932.700111.9S2 T4 C289 V290 S291 A297 T325S2-Q293 PolarHBondContact O-NE2 3.11Å; T4-Q293 HydrophobicContact CG2-CG 4.28Å; C289-Q293 WeakPolarHBondContact O-CB 3.39Å; C289-Q293 PolarHBondContact O-N 2.96Å; V290-Q293 WeakPolarHBondContact O-CB 3.15Å; V290-Q293 PolarHBondContact O-N 3.23Å; S291-Q293 VanDerWaalsContact C-N 3.33Å; S291-Q293 PolarHBondContact O-N 3.46Å; Q293-A297 WeakPolarHBondContact O-CB 3.3Å; Q293-A297 PolarHBondContact O-N 3.16Å; Q293-T325 HydrophobicContact CB-CG2 4.33Å
294R97Very high97.5Very high83 Ų8328 Ų2831%0.31315%0.151SC..Hα-helixtrans-64.5-42.3177.4-66.1-63.6-175.5-82.9-6.7111.9L248 D249 L252 V290 S291 L292 A297L248-R294 HydrophobicContact CD2-CB 4.35Å; L248-R294 HydrophobicContact CD2-CG 4.44Å; D249-R294 WeakPolarHBondContact OD1-CD 3.35Å; D249-R294 IonicContact OD1-CZ 3.53Å; D249-R294 IonicContact OD1-NE 2.71Å; D249-R294 PolarHBondContact OD1-NE 3.37Å; D249-R294 IonicContact OD2-NE 2.77Å; D249-R294 IonicContact OD2-NH2 3.96Å; L252-R294 HydrophobicContact CD2-CB 3.75Å; V290-R294 HydrophobicContact CG1-CG 4.42Å; V290-R294 VanDerWaalsContact O-CG 3.31Å; V290-R294 WeakPolarHBondContact O-CG 3.41Å; V290-R294 PolarHBondContact O-N 2.97Å; S291-R294 PolarHBondContact O-N 2.83Å; L292-R294 VanDerWaalsContact C-N 3.34Å; L292-R294 PolarHBondContact O-N 3.43Å; R294-A297 PolarHBondContact O-N 2.91Å
295I96.9Very high97.5Very high1 Ų127.5 Ų27.51%0.00515%0.148CC..Hα-helixtrans-67.3-47.3179-66.8166000110.8V177 L252 I264 V266 S291 L292 A297 L298V177-I295 HydrophobicContact CB-CD1 4.5Å; V177-I295 HydrophobicContact CG1-CD1 4.16Å; L252-I295 HydrophobicContact CD1-CG1 4.29Å; L252-I295 HydrophobicContact CD2-CG1 3.85Å; I264-I295 HydrophobicContact CD1-CG2 3.64Å; I264-I295 HydrophobicContact CG2-CG2 4.03Å; V266-I295 HydrophobicContact CG1-CD1 3.96Å; V266-I295 HydrophobicContact CG2-CD1 4.07Å; V266-I295 HydrophobicContact CG2-CG2 3.79Å; S291-I295 WeakPolarHBondContact O-CG1 3.27Å; S291-I295 PolarHBondContact O-N 2.76Å; L292-I295 PolarHBondContact O-N 2.9Å; I295-A297 PolarHBondContact O-N 3.35Å; I295-L298 VanDerWaalsContact O-CB 3.24Å; I295-L298 WeakPolarHBondContact O-CB 3.47Å; I295-L298 WeakPolarHBondContact O-CG 3.49Å; I295-L298 PolarHBondContact O-N 2.92Å
296L96.6Very high97.5Very high16 Ų1627.3 Ų27.38%0.08415%0.147CC..Hα-helixtrans-63.9-29.5178.2-68.5179.9000112.5T4 V135 L292 L298 N299 C302 A326T4-L296 HydrophobicContact CG2-CB 4.39Å; T4-L296 HydrophobicContact CG2-CD1 4.47Å; V135-L296 HydrophobicContact CG2-CD2 3.72Å; L292-L296 HydrophobicContact CD1-CD1 3.85Å; L292-L296 HydrophobicContact CD1-CD2 4.29Å; L292-L296 HydrophobicContact CD1-CG 3.78Å; L292-L296 HydrophobicContact CD2-CD1 4.49Å; L292-L296 HydrophobicContact CG-CD1 3.87Å; L292-L296 HydrophobicContact CG-CG 4.2Å; L292-L296 WeakPolarHBondContact O-CB 3.35Å; L292-L296 VanDerWaalsContact O-CG 3.29Å; L292-L296 WeakPolarHBondContact O-CG 3.19Å; L292-L296 PolarHBondContact O-N 3.39Å; L296-L298 PolarHBondContact O-N 3.35Å; L296-L298 VanDerWaalsContact O-N 3.15Å; L296-N299 PolarHBondContact O-N 3.24Å; L296-C302 HydrophobicContact CD2-CB 4.05Å; L296-A326 HydrophobicContact CD1-CB 4.24Å
297A95.5Very high97.5Very high44 Ų4422.7 Ų22.736%0.36412%0.123SC..THydrogen-bonded Turntrans-64.6-12.7174.100000113.7Q293 R294 I295 N299Q293-A297 WeakPolarHBondContact O-CB 3.3Å; Q293-A297 PolarHBondContact O-N 3.16Å; R294-A297 PolarHBondContact O-N 2.91Å; I295-A297 PolarHBondContact O-N 3.35Å; A297-N299 PolarHBondContact O-N 2.8Å; A297-N299 PolarHBondContact O-ND2 3.43Å
298L94.4Very high97.4Very high42 Ų4222.8 Ų22.822%0.2212%0.124CC..THydrogen-bonded Turntrans-72.9-9.6170.5-56.4177.8000113L252 R256 I264 I295 L296 M300L252-L298 HydrophobicContact CD1-CD1 4.1Å; L252-L298 HydrophobicContact CG-CD1 4.34Å; R256-L298 HydrophobicContact CB-CD2 4.25Å; R256-L298 HydrophobicContact CG-CD2 4.16Å; I264-L298 HydrophobicContact CD1-CB 4.36Å; I264-L298 HydrophobicContact CD1-CD1 3.86Å; I295-L298 VanDerWaalsContact O-CB 3.24Å; I295-L298 WeakPolarHBondContact O-CB 3.47Å; I295-L298 WeakPolarHBondContact O-CG 3.49Å; I295-L298 PolarHBondContact O-N 2.92Å; L296-L298 PolarHBondContact O-N 3.35Å; L296-L298 VanDerWaalsContact O-N 3.15Å; L298-M300 VanDerWaalsContact C-N 3.35Å; L298-M300 HydrophobicContact CB-CE 3.48Å; L298-M300 VanDerWaalsContact CB-CE 3.48Å; L298-M300 HydrophobicContact CD1-CE 3.77Å; L298-M300 HydrophobicContact CG-CE 4.24Å; L298-M300 PolarHBondContact O-N 2.99Å
299N94.3Very high97.4Very high148 Ų14822.8 Ų22.879%0.79112%0.124SC*.  trans54.642.9174.3-63.3-68.1000114.3L296 A297L296-N299 PolarHBondContact O-N 3.24Å; A297-N299 PolarHBondContact O-N 2.8Å; A297-N299 PolarHBondContact O-ND2 3.43Å
300M95.9Very high97.3Very high24 Ų2423.7 Ų23.712%0.11813%0.126CC..SBendtrans-114.8157.2176.6-69.6-179.7-72.600111.2P261 I264 L298 C302P261-M300 HydrophobicContact CB-CE 4.37Å; P261-M300 HydrophobicContact CB-SD 4.11Å; P261-M300 HydrophobicContact CG-CE 3.64Å; P261-M300 HydrophobicContact CG-SD 3.84Å; I264-M300 HydrophobicContact CD1-CB 4.39Å; I264-M300 HydrophobicContact CD1-CE 3.44Å; I264-M300 VanDerWaalsContact CD1-CE 3.44Å; I264-M300 HydrophobicContact CG1-CB 4.25Å; I264-M300 HydrophobicContact CG1-CE 3.68Å; I264-M300 HydrophobicContact CG1-SD 4.49Å; L298-M300 VanDerWaalsContact C-N 3.35Å; L298-M300 HydrophobicContact CB-CE 3.48Å; L298-M300 VanDerWaalsContact CB-CE 3.48Å; L298-M300 HydrophobicContact CD1-CE 3.77Å; L298-M300 HydrophobicContact CG-CE 4.24Å; L298-M300 PolarHBondContact O-N 2.99Å; M300-C302 PolarHBondContact O-N 3.19Å
301P98.5Very high97.2Very high30 Ų3026 Ų2620%0.19513%0.134CC..  trans-49.8122.9166.9-24.934.1000110.3L128 K134 Y171 H262 A263 I264L128-P301 HydrophobicContact CB-CB 4.34Å; L128-P301 HydrophobicContact CD2-CB 4.07Å; K134-P301 WeakPolarHBondContact O-CA 3.31Å; Y171-P301 HydrophobicContact CE1-CG 3.87Å; Y171-P301 HydrophobicContact CE2-CB 4.3Å; Y171-P301 HydrophobicContact CE2-CG 4.42Å; Y171-P301 WeakPolarHBondContact OH-CG 3.35Å; H262-P301 WeakPolarHBondContact O-CD 3.5Å; A263-P301 CarbonylContact C-O 3.53Å; A263-P301 WeakPolarHBondContact CA-O 3.49Å; A263-P301 HydrophobicContact CB-CB 4.12Å; I264-P301 PolarHBondContact N-O 2.77Å
302C98.7Very high97.2Very high1 Ų126.4 Ų26.41%0.00714%0.138CC..EExtended strand (participates in β ladder)trans-130.7122.5-170.3-164.60000111.4K134 V135 S136 I264 L296 M300K134-C302 PolarHBondContact O-N 3Å; V135-C302 CarbonylContact C-O 3.59Å; V135-C302 VanDerWaalsContact CA-O 3.24Å; V135-C302 WeakPolarHBondContact CA-O 3.38Å; V135-C302 HydrophobicContact CG2-CB 4.41Å; S136-C302 PolarHBondContact N-O 3.39Å; I264-C302 CarbonylContact O-C 3.37Å; I264-C302 WeakPolarHBondContact O-CA 3.35Å; L296-C302 HydrophobicContact CD2-CB 4.05Å; M300-C302 PolarHBondContact O-N 3.19Å
303L98.9Very high97.2Very high0 Ų027.4 Ų27.40%014%0.144CC..EExtended strand (participates in β ladder)trans-98123.6171172.957.9000109C124 A125 L128 S136 S163 I264 V265 V266 L305C124-L303 HydrophobicContact CB-CD1 3.38Å; A125-L303 HydrophobicContact CB-CD2 4.49Å; L128-L303 HydrophobicContact CD1-CB 3.84Å; S136-L303 CarbonylContact O-C 3.6Å; S136-L303 WeakPolarHBondContact O-CA 3.41Å; S163-L303 VanDerWaalsContact CB-CD2 3.44Å; S163-L303 WeakPolarHBondContact OG-CD2 3.4Å; I264-L303 PolarHBondContact O-N 3.38Å; V265-L303 CarbonylContact C-O 3.38Å; V265-L303 WeakPolarHBondContact CA-O 3.16Å; V265-L303 HydrophobicContact CG1-CB 4.4Å; V265-L303 HydrophobicContact CG1-CD2 4.13Å; V265-L303 HydrophobicContact CG1-CG 4.26Å; V265-L303 HydrophobicContact CG2-CB 4.17Å; V265-L303 HydrophobicContact CG2-CD2 4.21Å; V266-L303 PolarHBondContact N-O 3Å; L303-L305 HydrophobicContact CD1-CD2 3.94Å; L303-L305 HydrophobicContact CD2-CD1 4.42Å; L303-L305 HydrophobicContact CD2-CD2 4.11Å; L303-L305 HydrophobicContact CD2-CG 4.31Å; L303-L305 HydrophobicContact CG-CD2 3.94Å; L303-L305 HydrophobicContact CG-CG 4.04Å
304L98.9Very high97.2Very high2 Ų226.6 Ų26.61%0.0114%0.14CC..EExtended strand (participates in β ladder)trans-104.4122.9174.8-51.3-176.8000109.7V135 S136 I137 N138 V266 L268 L292 A326V135-L304 HydrophobicContact CG1-CD1 3.86Å; V135-L304 HydrophobicContact CG1-CG 3.95Å; S136-L304 PolarHBondContact O-N 2.93Å; I137-L304 CarbonylContact C-O 3.58Å; I137-L304 WeakPolarHBondContact CA-O 3.34Å; I137-L304 HydrophobicContact CD1-CD1 4.14Å; I137-L304 HydrophobicContact CG1-CB 4.16Å; I137-L304 HydrophobicContact CG1-CD1 4.06Å; I137-L304 HydrophobicContact CG1-CG 4.34Å; I137-L304 HydrophobicContact CG2-CB 4.3Å; N138-L304 PolarHBondContact N-O 3.42Å; V266-L304 HydrophobicContact CB-CD2 3.89Å; V266-L304 HydrophobicContact CG2-CD2 3.92Å; L268-L304 HydrophobicContact CD1-CB 4.21Å; L268-L304 HydrophobicContact CD1-CD2 4.29Å; L292-L304 HydrophobicContact CD1-CD1 3.69Å; L292-L304 HydrophobicContact CD1-CD2 3.56Å; L292-L304 HydrophobicContact CD1-CG 4.3Å; L292-L304 HydrophobicContact CD2-CD1 4.17Å; L304-A326 HydrophobicContact CD1-CB 4.5Å
305L98.9Very high97.3Very high0 Ų022.7 Ų22.70%013%0.126CC..EExtended strand (participates in β ladder)trans-113.6157.9179.5-61.7178.9000111.1S121 N138 C160 V265 V266 L268 L303 W319S121-L305 WeakPolarHBondContact OG-CD2 3.42Å; N138-L305 HydrophobicContact CB-CD2 4.07Å; N138-L305 WeakPolarHBondContact O-CA 3.47Å; C160-L305 HydrophobicContact CB-CD1 4.31Å; V265-L305 HydrophobicContact CG1-CD1 3.8Å; V265-L305 HydrophobicContact CG1-CG 4.33Å; V266-L305 PolarHBondContact O-N 2.82Å; L268-L305 WeakPolarHBondContact CB-O 3.22Å; L268-L305 PolarHBondContact N-O 3.05Å; L303-L305 HydrophobicContact CD1-CD2 3.94Å; L303-L305 HydrophobicContact CD2-CD1 4.42Å; L303-L305 HydrophobicContact CD2-CD2 4.11Å; L303-L305 HydrophobicContact CD2-CG 4.31Å; L303-L305 HydrophobicContact CG-CD2 3.94Å; L303-L305 HydrophobicContact CG-CG 4.04Å; L305-W319 VanDerWaalsContact O-CH2 3.24Å; L305-W319 WeakPolarHBondContact O-CH2 3.29Å; L305-W319 WeakPolarHBondContact O-CZ2 3.36Å
306G98.5Very high97.4Very high0 Ų022.7 Ų22.70%013%0.126CC..  trans-64.7-137.8169.500000113.8N138 L139 G141 Q267 L268 G269 W319N138-G306 PolarHBondContact O-N 3.34Å; N138-G306 VanDerWaalsContact O-N 3.1Å; L139-G306 VanDerWaalsContact O-CA 3.28Å; L139-G306 WeakPolarHBondContact O-CA 3.41Å; G141-G306 CarbonylContact O-C 3.51Å; G141-G306 WeakPolarHBondContact O-CA 3.49Å; G141-G306 PolarHBondContact O-N 2.93Å; Q267-G306 WeakPolarHBondContact CG-O 3.42Å; L268-G306 CarbonylContact C-O 3.57Å; L268-G306 PolarHBondContact N-O 3.34Å; L268-G306 VanDerWaalsContact N-O 3.13Å; G269-G306 PolarHBondContact N-O 3.49Å; G306-W319 VanDerWaalsContact CA-CZ2 3.49Å
307G97.3Very high97.5Very high1 Ų122.4 Ų22.41%0.0112%0.124CC..  trans144-150.9-179.900000113R33 G141R33-G307 PolarHBondContact NH1-O 3.41Å; R33-G307 PolarHBondContact NH2-O 3.45Å; G141-G307 PolarHBondContact O-N 3.24Å
308G96.8Very high97.6Very high2 Ų220.3 Ų20.32%0.02111%0.106CC..  trans-60.1168.5169.900000113.6D180 G269 V270 D271D180-G308 WeakPolarHBondContact OD2-CA 3.5Å; D180-G308 PolarHBondContact OD2-N 2.98Å; G269-G308 WeakPolarHBondContact CA-O 3.22Å; V270-G308 PolarHBondContact N-O 2.99Å; D271-G308 WeakPolarHBondContact OD2-CA 3.29Å
309G97.6Very high97.8Very high1 Ų118.5 Ų18.51%0.0110%0.097CC..  trans133.996.2178.700000110.4R33R33-G309 PolarHBondContact NH1-O 2.98Å
310Y97.1Very high98Very high35 Ų3511.4 Ų11.414%0.1376%0.059CC..  trans-108.81.6-162.8-50.9-81.3000112.6F154 D271 D276 N278 P312F154-Y310 HydrophobicContact CD2-CE1 4.16Å; F154-Y310 HydrophobicContact CE2-CE1 4.11Å; D271-Y310 HydrophobicContact CB-CD2 3.92Å; D271-Y310 HydrophobicContact CB-CE2 3.83Å; D271-Y310 WeakPolarHBondContact OD2-CE2 3.39Å; D276-Y310 PolarHBondContact OD2-N 3.33Å; N278-Y310 VanDerWaalsContact ND2-CD2 3.34Å; N278-Y310 WeakPolarHBondContact ND2-CD2 3.35Å; N278-Y310 WeakPolarHBondContact ND2-CE2 3.42Å; Y310-P312 WeakPolarHBondContact O-CD 3.24Å
311Q97.1Very high98.2Very high75 Ų7512.3 Ų12.335%0.356%0.063SC..  trans-99.798.9162.8178.757.4-39.600110.7D276 V313 N314 F315D276-Q311 PolarHBondContact OD2-N 2.93Å; Q311-V313 VanDerWaalsContact C-N 3.33Å; Q311-V313 PolarHBondContact O-N 2.89Å; Q311-N314 HydrophobicContact CB-CB 4.2Å; Q311-N314 HydrophobicContact CG-CB 3.85Å; Q311-N314 PolarHBondContact O-N 3.44Å; Q311-N314 VanDerWaalsContact O-N 3.08Å; Q311-F315 PolarHBondContact O-N 2.94Å
312P97.2Very high98.2Very high10 Ų1011 Ų117%0.0655%0.054CC..Hα-helixtrans-57.2-38.9-168.1-28.636.1000115K31 R33 M36 Y310 F315 A316K31-P312 HydrophobicContact CB-CG 3.7Å; K31-P312 HydrophobicContact CD-CG 4.43Å; R33-P312 HydrophobicContact CB-CB 3.84Å; R33-P312 HydrophobicContact CB-CG 4.36Å; M36-P312 HydrophobicContact CE-CB 3.77Å; M36-P312 HydrophobicContact SD-CB 4.14Å; Y310-P312 WeakPolarHBondContact O-CD 3.24Å; P312-F315 PolarHBondContact O-N 2.9Å; P312-A316 WeakPolarHBondContact O-CB 3.49Å; P312-A316 PolarHBondContact O-N 3.38Å
313V97.9Very high98.1Very high21 Ų2111.1 Ų11.113%0.1275%0.054CC..Hα-helixtrans-64.7-45.6179173.10000110.6M36 Q311 A316 K317 L343 Y344M36-V313 HydrophobicContact CE-CG2 4.43Å; M36-V313 HydrophobicContact SD-CB 4.5Å; M36-V313 HydrophobicContact SD-CG2 4Å; Q311-V313 VanDerWaalsContact C-N 3.33Å; Q311-V313 PolarHBondContact O-N 2.89Å; V313-A316 PolarHBondContact O-N 3.39Å; V313-K317 HydrophobicContact CG1-CD 4.24Å; V313-K317 WeakPolarHBondContact O-CB 3.29Å; V313-K317 VanDerWaalsContact O-CG 3.31Å; V313-K317 WeakPolarHBondContact O-CG 3.07Å; V313-K317 PolarHBondContact O-N 2.84Å; V313-L343 HydrophobicContact CG2-CB 4.15Å; V313-L343 WeakPolarHBondContact CG2-O 3.47Å; V313-Y344 HydrophobicContact CG1-CD1 3.69Å; V313-Y344 HydrophobicContact CG1-CE1 3.94Å; V313-Y344 HydrophobicContact CG1-CG 4.39Å
314N98Very high98.1Very high22 Ų2211.3 Ų11.312%0.1186%0.056CC..Hα-helixtrans-69.3-38179.2-71.34.3000111.1L273 T274 Q311 K317 C318 I352L273-N314 HydrophobicContact CD1-CB 4.14Å; T274-N314 PolarHBondContact O-ND2 3.3Å; Q311-N314 HydrophobicContact CB-CB 4.2Å; Q311-N314 HydrophobicContact CG-CB 3.85Å; Q311-N314 PolarHBondContact O-N 3.44Å; Q311-N314 VanDerWaalsContact O-N 3.08Å; N314-K317 PolarHBondContact O-N 3.26Å; N314-C318 VanDerWaalsContact O-CB 3.29Å; N314-C318 WeakPolarHBondContact O-CB 3.41Å; N314-C318 PolarHBondContact O-N 2.88Å; N314-I352 HydrophobicContact CB-CD1 3.73Å
315F98.4Very high98Very high2 Ų212.7 Ų12.71%0.0096%0.064CC..Hα-helixtrans-57.2-49.9172.1-174.7-80.9000110.9R33 T37 L139 V270 Q311 P312 C318 W319R33-F315 HydrophobicContact CB-CD1 4.21Å; R33-F315 HydrophobicContact CB-CG 4.46Å; R33-F315 HydrophobicContact CG-CD1 4.1Å; R33-F315 HydrophobicContact CG-CE1 4.24Å; R33-F315 HydrophobicContact CG-CG 4.42Å; T37-F315 HydrophobicContact CG2-CE1 4.43Å; T37-F315 VanDerWaalsContact OG1-CD1 3.3Å; T37-F315 WeakPolarHBondContact OG1-CD1 3.41Å; L139-F315 HydrophobicContact CD1-CE1 4.13Å; L139-F315 HydrophobicContact CD1-CZ 4.47Å; V270-F315 HydrophobicContact CG2-CB 4.19Å; V270-F315 HydrophobicContact CG2-CD2 3.29Å; V270-F315 HydrophobicContact CG2-CE2 3.89Å; V270-F315 HydrophobicContact CG2-CG 3.98Å; Q311-F315 PolarHBondContact O-N 2.94Å; P312-F315 PolarHBondContact O-N 2.9Å; F315-C318 PolarHBondContact O-N 2.88Å; F315-W319 AromaticContact CD1-CD1 3.84Å; F315-W319 AromaticContact CE1-CD1 3.45Å; F315-W319 VanDerWaalsContact CE1-CD1 3.45Å; F315-W319 HydrophobicContact CE1-CG 4.05Å; F315-W319 AromaticContact CE1-NE1 4Å; F315-W319 AromaticContact CE2-CD1 3.66Å; F315-W319 AromaticContact CE2-NE1 3.58Å; F315-W319 AromaticContact CZ-CD1 3.35Å; F315-W319 HydrophobicContact CZ-CG 4.21Å; F315-W319 AromaticContact CZ-NE1 3.4Å; F315-W319 WeakPolarHBondContact O-CB 3.4Å; F315-W319 PolarHBondContact O-N 3.21Å
316A98.6Very high97.9Very high0 Ų012.7 Ų12.70%06%0.064CC..Hα-helixtrans-61.9-48.2178.400000112.2M36 T37 L40 P312 V313 C318 W319 A320 Y344M36-A316 HydrophobicContact CG-CB 3.9Å; M36-A316 HydrophobicContact SD-CB 4.05Å; T37-A316 WeakPolarHBondContact OG1-CA 3.49Å; L40-A316 HydrophobicContact CD2-CB 4.09Å; P312-A316 WeakPolarHBondContact O-CB 3.49Å; P312-A316 PolarHBondContact O-N 3.38Å; V313-A316 PolarHBondContact O-N 3.39Å; A316-C318 VanDerWaalsContact C-N 3.32Å; A316-C318 PolarHBondContact O-N 3.46Å; A316-W319 PolarHBondContact O-N 3.36Å; A316-A320 WeakPolarHBondContact O-CB 2.98Å; A316-A320 PolarHBondContact O-N 3.43Å; A316-Y344 WeakPolarHBondContact CB-OH 3.43Å
317K98.6Very high97.8Very high10 Ų1013.3 Ų13.34%0.0437%0.068CC..Hα-helixtrans-56.7-44.3176.5-73-179.8-178.8-166.60111.6V313 N314 Q321 I335 Y344 D347 V349 L350 I352V313-K317 HydrophobicContact CG1-CD 4.24Å; V313-K317 WeakPolarHBondContact O-CB 3.29Å; V313-K317 VanDerWaalsContact O-CG 3.31Å; V313-K317 WeakPolarHBondContact O-CG 3.07Å; V313-K317 PolarHBondContact O-N 2.84Å; N314-K317 PolarHBondContact O-N 3.26Å; K317-Q321 WeakPolarHBondContact O-CG 3.21Å; K317-Q321 PolarHBondContact O-N 2.85Å; K317-Q321 PolarHBondContact O-NE2 3.43Å; K317-I335 HydrophobicContact CG-CD1 4.41Å; K317-Y344 HydrophobicContact CG-CD1 4.23Å; K317-Y344 HydrophobicContact CG-CE1 4Å; K317-D347 IonicContact NZ-OD1 2.8Å; K317-V349 WeakPolarHBondContact CE-O 3.4Å; K317-V349 PolarHBondContact NZ-O 3.1Å; K317-L350 HydrophobicContact CB-CD1 4.04Å; K317-L350 HydrophobicContact CG-CD1 4.18Å; K317-I352 HydrophobicContact CB-CD1 4.14Å; K317-I352 HydrophobicContact CB-CG1 4.39Å; K317-I352 HydrophobicContact CD-CD1 4.35Å; K317-I352 HydrophobicContact CD-CG1 3.93Å
318C98.7Very high97.6Very high0 Ų015.3 Ų15.30%09%0.089CC..Hα-helixtrans-71.7-46.6-178.2-167.30000112V270 L273 P285 N314 F315 A316 A320 Q321 L322V270-C318 HydrophobicContact CG1-CB 4.25Å; L273-C318 HydrophobicContact CD1-CB 3.64Å; P285-C318 HydrophobicContact CB-CB 4.35Å; P285-C318 HydrophobicContact CG-CB 4.05Å; N314-C318 VanDerWaalsContact O-CB 3.29Å; N314-C318 WeakPolarHBondContact O-CB 3.41Å; N314-C318 PolarHBondContact O-N 2.88Å; F315-C318 PolarHBondContact O-N 2.88Å; A316-C318 VanDerWaalsContact C-N 3.32Å; A316-C318 PolarHBondContact O-N 3.46Å; C318-A320 VanDerWaalsContact C-N 3.34Å; C318-A320 PolarHBondContact O-N 2.8Å; C318-Q321 WeakPolarHBondContact O-CB 3.21Å; C318-Q321 PolarHBondContact O-N 3.48Å; C318-Q321 VanDerWaalsContact O-N 3.11Å; C318-L322 WeakPolarHBondContact O-CG 3.42Å; C318-L322 PolarHBondContact O-N 3.19Å
319W98.7Very high97.6Very high4 Ų419.8 Ų19.82%0.01511%0.108CC..Hα-helixtrans-66.3-33.5179.5-91.994.4000113.2T37 M41 I137 L139 L268 L305 G306 F315 A316 Q321 L322 L323T37-W319 HydrophobicContact CG2-CB 3.6Å; T37-W319 HydrophobicContact CG2-CG 4.48Å; M41-W319 VanDerWaalsContact CE-C 3.42Å; M41-W319 HydrophobicContact CE-CB 3.85Å; M41-W319 HydrophobicContact CE-CE3 4.39Å; M41-W319 WeakPolarHBondContact CE-O 3.33Å; I137-W319 HydrophobicContact CG2-CZ3 3.84Å; L139-W319 HydrophobicContact CB-CD2 3.78Å; L139-W319 HydrophobicContact CB-CE3 3.56Å; L139-W319 HydrophobicContact CB-CH2 3.9Å; L139-W319 HydrophobicContact CB-CZ2 4.13Å; L139-W319 HydrophobicContact CB-CZ3 3.61Å; L139-W319 HydrophobicContact CD2-CE3 4.4Å; L268-W319 HydrophobicContact CB-CH2 4.06Å; L268-W319 HydrophobicContact CB-CZ2 3.62Å; L268-W319 HydrophobicContact CD1-CH2 4Å; L268-W319 HydrophobicContact CD1-CZ2 4.39Å; L268-W319 PolarHBondContact O-NE1 3.1Å; L305-W319 VanDerWaalsContact O-CH2 3.24Å; L305-W319 WeakPolarHBondContact O-CH2 3.29Å; L305-W319 WeakPolarHBondContact O-CZ2 3.36Å; G306-W319 VanDerWaalsContact CA-CZ2 3.49Å; F315-W319 AromaticContact CD1-CD1 3.84Å; F315-W319 AromaticContact CE1-CD1 3.45Å; F315-W319 VanDerWaalsContact CE1-CD1 3.45Å; F315-W319 HydrophobicContact CE1-CG 4.05Å; F315-W319 AromaticContact CE1-NE1 4Å; F315-W319 AromaticContact CE2-CD1 3.66Å; F315-W319 AromaticContact CE2-NE1 3.58Å; F315-W319 AromaticContact CZ-CD1 3.35Å; F315-W319 HydrophobicContact CZ-CG 4.21Å; F315-W319 AromaticContact CZ-NE1 3.4Å; F315-W319 WeakPolarHBondContact O-CB 3.4Å; F315-W319 PolarHBondContact O-N 3.21Å; A316-W319 PolarHBondContact O-N 3.36Å; W319-Q321 VanDerWaalsContact C-N 3.34Å; W319-L322 HydrophobicContact CD2-CD1 4.09Å; W319-L322 HydrophobicContact CE3-CB 4.46Å; W319-L322 HydrophobicContact CE3-CD1 4.4Å; W319-L322 HydrophobicContact CG-CD1 4.34Å; W319-L322 PolarHBondContact O-N 3.07Å; W319-L323 PolarHBondContact O-N 2.63Å
320A98.7Very high97.4Very high0 Ų025.7 Ų25.70%015%0.149CC..Hα-helixtrans-60.7-43.8170.300000111.6L40 M41 Y44 L46 A316 C318 S324 L331L40-A320 HydrophobicContact CD2-CB 3.86Å; L40-A320 HydrophobicContact CG-CB 4.23Å; M41-A320 HydrophobicContact CG-CB 4.37Å; Y44-A320 HydrophobicContact CD2-CB 4.48Å; L46-A320 WeakPolarHBondContact CD1-O 3.42Å; A316-A320 WeakPolarHBondContact O-CB 2.98Å; A316-A320 PolarHBondContact O-N 3.43Å; C318-A320 VanDerWaalsContact C-N 3.34Å; C318-A320 PolarHBondContact O-N 2.8Å; A320-S324 WeakPolarHBondContact O-CB 3.32Å; A320-S324 PolarHBondContact O-N 3.37Å; A320-L331 HydrophobicContact CB-CD1 4.36Å
321Q98.6Very high97.4Very high43 Ų4326 Ų2620%0.20115%0.153CC..Hα-helixtrans-67.6-37175.9-71.817582.600112.8K317 C318 W319 S324 T325 L331 L350K317-Q321 WeakPolarHBondContact O-CG 3.21Å; K317-Q321 PolarHBondContact O-N 2.85Å; K317-Q321 PolarHBondContact O-NE2 3.43Å; C318-Q321 WeakPolarHBondContact O-CB 3.21Å; C318-Q321 PolarHBondContact O-N 3.48Å; C318-Q321 VanDerWaalsContact O-N 3.11Å; W319-Q321 VanDerWaalsContact C-N 3.34Å; Q321-S324 WeakPolarHBondContact O-CB 3.24Å; Q321-S324 PolarHBondContact O-N 2.76Å; Q321-T325 WeakPolarHBondContact O-CB 3.46Å; Q321-T325 PolarHBondContact O-N 2.99Å; Q321-T325 PolarHBondContact O-OG1 3.02Å; Q321-L331 HydrophobicContact CG-CD1 4.3Å; Q321-L350 HydrophobicContact CG-CD1 4.2Å; Q321-L350 HydrophobicContact CG-CD2 3.6Å; Q321-L350 HydrophobicContact CG-CG 3.89Å; Q321-L350 PolarHBondContact NE2-O 3.25Å
322L98.5Very high97.4Very high2 Ų227.2 Ų27.21%0.0117%0.165CC..Hα-helixtrans-62.9-47.3174.9-75.8166.6000111.5L268 V270 L292 C318 W319 S324 T325 A326L268-L322 HydrophobicContact CB-CD1 4.33Å; L268-L322 HydrophobicContact CD1-CD1 4.25Å; L268-L322 HydrophobicContact CD1-CD2 4.3Å; L268-L322 HydrophobicContact CD2-CD2 4.33Å; V270-L322 HydrophobicContact CG1-CD1 4.35Å; L292-L322 HydrophobicContact CB-CD2 4.09Å; L292-L322 HydrophobicContact CD2-CB 4.28Å; L292-L322 HydrophobicContact CD2-CD2 3.72Å; L292-L322 WeakPolarHBondContact CD2-O 3.22Å; C318-L322 WeakPolarHBondContact O-CG 3.42Å; C318-L322 PolarHBondContact O-N 3.19Å; W319-L322 HydrophobicContact CD2-CD1 4.09Å; W319-L322 HydrophobicContact CE3-CB 4.46Å; W319-L322 HydrophobicContact CE3-CD1 4.4Å; W319-L322 HydrophobicContact CG-CD1 4.34Å; W319-L322 PolarHBondContact O-N 3.07Å; L322-S324 VanDerWaalsContact C-N 3.32Å; L322-S324 PolarHBondContact O-N 2.84Å; L322-T325 WeakPolarHBondContact O-CB 3.28Å; L322-T325 PolarHBondContact O-N 3.36Å; L322-A326 PolarHBondContact O-N 3.26Å
323L98.1Very high97.4Very high3 Ų331.9 Ų31.92%0.01619%0.186CC..Hα-helixtrans-62.7-42175.517959.3000111.2L14 M41 L46 V50 I137 W319 T325 A326 V327L14-L323 HydrophobicContact CD2-CD2 4.25Å; M41-L323 HydrophobicContact CB-CD2 4.32Å; M41-L323 HydrophobicContact CE-CB 3.88Å; M41-L323 HydrophobicContact CE-CD2 4.02Å; M41-L323 HydrophobicContact CG-CD2 4Å; M41-L323 HydrophobicContact SD-CD2 3.59Å; M41-L323 VanDerWaalsContact SD-CD2 3.59Å; L46-L323 HydrophobicContact CB-CD2 3.68Å; L46-L323 HydrophobicContact CB-CG 4.19Å; L46-L323 HydrophobicContact CD1-CB 4.16Å; L46-L323 HydrophobicContact CD1-CD2 4.02Å; L46-L323 HydrophobicContact CD1-CG 4.12Å; L46-L323 HydrophobicContact CG-CD2 4.46Å; V50-L323 HydrophobicContact CG1-CD1 3.82Å; I137-L323 HydrophobicContact CD1-CD1 3.73Å; W319-L323 PolarHBondContact O-N 2.63Å; L323-T325 VanDerWaalsContact C-N 3.3Å; L323-T325 PolarHBondContact O-N 2.87Å; L323-A326 PolarHBondContact O-N 3.35Å; L323-V327 HydrophobicContact CD1-CG1 4.21Å; L323-V327 WeakPolarHBondContact O-CG2 3.41Å; L323-V327 PolarHBondContact O-N 3.28Å
324S97.6Very high97.4Very high4 Ų436.4 Ų36.43%0.02821%0.209CC..Hα-helixtrans-60.1-40.2175.2-159.90000112.5A320 Q321 L322 V327 G328 K329 L331A320-S324 WeakPolarHBondContact O-CB 3.32Å; A320-S324 PolarHBondContact O-N 3.37Å; Q321-S324 WeakPolarHBondContact O-CB 3.24Å; Q321-S324 PolarHBondContact O-N 2.76Å; L322-S324 VanDerWaalsContact C-N 3.32Å; L322-S324 PolarHBondContact O-N 2.84Å; S324-V327 PolarHBondContact O-N 2.95Å; S324-G328 PolarHBondContact O-N 3.48Å; S324-K329 PolarHBondContact O-N 3.21Å; S324-K329 PolarHBondContact OG-O 3.47Å; S324-L331 WeakPolarHBondContact OG-CG 3.36Å
325T97.1Very high97.5Very high31 Ų3135.7 Ų35.719%0.1921%0.205CC..Hα-helixtrans-64.9-45.3175.8-62.60000111.2T4 C289 L292 Q293 Q321 L322 L323 V327 G328T4-T325 PolarHBondContact OG1-O 3.09Å; C289-T325 HydrophobicContact CB-CG2 4.42Å; L292-T325 HydrophobicContact CD2-CG2 4.32Å; L292-T325 HydrophobicContact CG-CG2 4.48Å; Q293-T325 HydrophobicContact CB-CG2 4.33Å; Q321-T325 WeakPolarHBondContact O-CB 3.46Å; Q321-T325 PolarHBondContact O-N 2.99Å; Q321-T325 PolarHBondContact O-OG1 3.02Å; L322-T325 WeakPolarHBondContact O-CB 3.28Å; L322-T325 PolarHBondContact O-N 3.36Å; L323-T325 VanDerWaalsContact C-N 3.3Å; L323-T325 PolarHBondContact O-N 2.87Å; T325-V327 VanDerWaalsContact C-N 3.29Å; T325-V327 PolarHBondContact O-N 2.83Å; T325-G328 PolarHBondContact O-N 3.11Å
326A96.6Very high97.5Very high0 Ų037.2 Ų37.20%022%0.216CC..Hα-helixtrans-60.3-38178.300000112.5L7 L292 L296 L304 L322 L323L7-A326 WeakPolarHBondContact CD1-O 3.45Å; L292-A326 HydrophobicContact CD2-CB 4.31Å; L296-A326 HydrophobicContact CD1-CB 4.24Å; L304-A326 HydrophobicContact CD1-CB 4.5Å; L322-A326 PolarHBondContact O-N 3.26Å; L323-A326 PolarHBondContact O-N 3.35Å
327V96Very high97.4Very high13 Ų1345.5 Ų45.58%0.07925%0.254CS..THydrogen-bonded Turntrans-97.65.9-178.3-57.30000114.3V12 L46 H49 V50 L323 S324 T325 K329V12-V327 HydrophobicContact CB-CG1 4.38Å; V12-V327 HydrophobicContact CG1-CG1 4.28Å; V12-V327 HydrophobicContact CG2-CG1 4.28Å; L46-V327 HydrophobicContact CD2-CG2 4.23Å; H49-V327 HydrophobicContact CB-CB 4.09Å; H49-V327 HydrophobicContact CB-CG1 4.34Å; H49-V327 HydrophobicContact CB-CG2 4.01Å; V50-V327 HydrophobicContact CG1-CG1 3.54Å; L323-V327 HydrophobicContact CD1-CG1 4.21Å; L323-V327 WeakPolarHBondContact O-CG2 3.41Å; L323-V327 PolarHBondContact O-N 3.28Å; S324-V327 PolarHBondContact O-N 2.95Å; T325-V327 VanDerWaalsContact C-N 3.29Å; T325-V327 PolarHBondContact O-N 2.83Å; V327-K329 VanDerWaalsContact C-N 3.34Å; V327-K329 HydrophobicContact CG2-CB 4.11Å; V327-K329 HydrophobicContact CG2-CG 3.76Å; V327-K329 PolarHBondContact O-N 3.35Å
328G94.8Very high97.4Very high43 Ų4346.1 Ų46.144%0.44326%0.257SS..THydrogen-bonded Turntrans62.636.9176.800000113.8S324 T325S324-G328 PolarHBondContact O-N 3.48Å; T325-G328 PolarHBondContact O-N 3.11Å
329K95Very high97.4Very high97 Ų9751.6 Ų51.642%0.42229%0.293SS..  trans-106.9150176.3-64.1-66.6169.6-173.90110.8L46 H49 S324 V327L46-K329 HydrophobicContact CD2-CB 4.38Å; H49-K329 VanDerWaalsContact CE1-CE 3.42Å; H49-K329 WeakPolarHBondContact CE1-CE 3.4Å; S324-K329 PolarHBondContact O-N 3.21Å; S324-K329 PolarHBondContact OG-O 3.47Å; V327-K329 VanDerWaalsContact C-N 3.34Å; V327-K329 HydrophobicContact CG2-CB 4.11Å; V327-K329 HydrophobicContact CG2-CG 3.76Å; V327-K329 PolarHBondContact O-N 3.35Å
330S94.3Very high97.3Very high124 Ų12453.5 Ų53.587%0.86730%0.301SS*.PPolyproline II helixtrans-99.3133.1171.3-59.10000108.4
331L96.8Very high97.3Very high42 Ų4256.2 Ų56.222%0.2231%0.313CS..PPolyproline II helixtrans-93.6146.3172.3-58-177.9000109.1Y44 L46 A320 Q321 S324 L350Y44-L331 HydrophobicContact CD1-CB 4.27Å; Y44-L331 HydrophobicContact CD1-CD2 3.79Å; Y44-L331 HydrophobicContact CD1-CG 4.42Å; Y44-L331 HydrophobicContact CD2-CD1 4.3Å; Y44-L331 HydrophobicContact CE1-CB 4.09Å; Y44-L331 HydrophobicContact CE1-CD2 4.44Å; Y44-L331 HydrophobicContact CE2-CD1 4.4Å; Y44-L331 HydrophobicContact CG-CD1 4.4Å; Y44-L331 HydrophobicContact CG-CD2 3.84Å; L46-L331 HydrophobicContact CD1-CD2 4.32Å; L46-L331 HydrophobicContact CD2-CD2 3.97Å; L46-L331 HydrophobicContact CG-CD2 4.27Å; A320-L331 HydrophobicContact CB-CD1 4.36Å; Q321-L331 HydrophobicContact CG-CD1 4.3Å; S324-L331 WeakPolarHBondContact OG-CG 3.36Å; L331-L350 HydrophobicContact CB-CD2 3.71Å; L331-L350 HydrophobicContact CD1-CD2 3.6Å; L331-L350 HydrophobicContact CG-CD2 4.28Å
332V97.3Very high97.3Very high100 Ų10059 Ų5961%0.60634%0.335SS*.PPolyproline II helixtrans-72151.9164.4-64.30000109.2Y44Y44-V332 HydrophobicContact CE1-CG2 3.92Å; Y44-V332 PolarHBondContact OH-O 3.19Å
333E97.7Very high97.2Very high109 Ų10963.5 Ų63.551%0.50936%0.358SS..SBendtrans-66.9-38.8-178.7180163.7-140.200111.8I335 V349 L350 T351E333-I335 PolarHBondContact O-N 2.91Å; E333-V349 HydrophobicContact CG-CB 3.76Å; E333-V349 HydrophobicContact CG-CG1 3.87Å; E333-V349 CarbonylContact O-C 3.51Å; E333-V349 WeakPolarHBondContact O-CA 3.43Å; E333-L350 WeakPolarHBondContact O-CB 3.42Å; E333-L350 PolarHBondContact O-N 3.1Å; E333-T351 PolarHBondContact OE1-OG1 3.09Å
334D98.2Very high97.2Very high115 Ų11563.5 Ų63.562%0.61536%0.358SS*.BIsolated β-bridgetrans-64132.9178.8-60.9-30.9000110.9Y44 P336Y44-D334 PolarHBondContact OH-O 3.08Å; D334-P336 WeakPolarHBondContact O-CD 3.34Å
335I98.6Very high97.1Very high8 Ų865 Ų654%0.04137%0.374CS..PPolyproline II helixtrans-70.3122.2171.7-62.9-72.5000107.8L40 Y44 K317 E333 F341 Y344 F348 L350L40-I335 HydrophobicContact CD1-CD1 4Å; L40-I335 HydrophobicContact CD1-CG2 3.8Å; L40-I335 HydrophobicContact CD2-CD1 4.43Å; Y44-I335 HydrophobicContact CE2-CD1 4.45Å; K317-I335 HydrophobicContact CG-CD1 4.41Å; E333-I335 PolarHBondContact O-N 2.91Å; I335-F341 HydrophobicContact CB-CE2 4.44Å; I335-F341 HydrophobicContact CG2-CD2 4.01Å; I335-F341 HydrophobicContact CG2-CE2 4.36Å; I335-F341 VanDerWaalsContact O-CE2 3.27Å; I335-F341 WeakPolarHBondContact O-CE2 3.43Å; I335-Y344 HydrophobicContact CD1-CD1 3.79Å; I335-Y344 HydrophobicContact CD1-CE1 4.03Å; I335-Y344 HydrophobicContact CD1-CG 4.47Å; I335-Y344 HydrophobicContact CG1-CD1 3.92Å; I335-Y344 HydrophobicContact CG1-CG 4.16Å; I335-Y344 HydrophobicContact CG2-CD1 4.21Å; I335-Y344 HydrophobicContact CG2-CD2 4.04Å; I335-Y344 HydrophobicContact CG2-CE2 4.39Å; I335-Y344 HydrophobicContact CG2-CG 3.95Å; I335-F348 WeakPolarHBondContact CB-O 3.42Å; I335-F348 WeakPolarHBondContact CG1-O 3.08Å; I335-F348 PolarHBondContact N-O 2.88Å; I335-L350 HydrophobicContact CD1-CB 4.24Å; I335-L350 HydrophobicContact CD1-CD1 4.01Å
336P98.3Very high97.1Very high34 Ų3469.4 Ų69.422%0.22140%0.404CS..PPolyproline II helixtrans-69154.6177.127.7-34.9000111.4A43 Y44 D334 H338A43-P336 HydrophobicContact CB-CB 4.08Å; A43-P336 HydrophobicContact CB-CG 3.56Å; Y44-P336 HydrophobicContact CD1-CG 4Å; Y44-P336 HydrophobicContact CD2-CG 4.15Å; Y44-P336 VanDerWaalsContact CE1-CD 3.49Å; Y44-P336 HydrophobicContact CE1-CG 4.06Å; Y44-P336 HydrophobicContact CE2-CG 4.22Å; Y44-P336 HydrophobicContact CG-CG 4.05Å; D334-P336 WeakPolarHBondContact O-CD 3.34Å; P336-H338 PolarHBondContact O-CD2 2.94Å; P336-H338 PolarHBondContact O-N 2.66Å
337E97.8Very high97Very high174 Ų17473.5 Ų73.581%0.81343%0.425SS*.PPolyproline II helixtrans-60.2132.1175-72.5-172-178.600111.8
338H98.3Very high97.1Very high23 Ų2376.1 Ų76.111%0.10644%0.436CS..  trans-162.1169.9175.778.7104.7000110.3S39 A43 P336 F340 F341 Y344S39-H338 PolarHBondContact OG-ND1 3.24Å; A43-H338 HydrophobicContact CB-CB 3.78Å; P336-H338 PolarHBondContact O-CD2 2.94Å; P336-H338 PolarHBondContact O-N 2.66Å; H338-F340 AromaticContact ND1-CD2 3.92Å; H338-F340 PolarHBondContact ND1-N 3.18Å; H338-F340 PolarHBondContact O-N 3.17Å; H338-F341 WeakPolarHBondContact O-CB 3.47Å; H338-F341 PolarHBondContact O-N 3.28Å; H338-Y344 AromaticContact CE1-CE2 3.65Å; H338-Y344 AromaticContact NE2-CD2 3.92Å; H338-Y344 AromaticContact NE2-CE2 3.07Å; H338-Y344 WeakPolarHBondContact NE2-CE2 3.07Å; H338-Y344 AromaticContact NE2-CZ 3.58Å
339P98Very high97.3Very high114 Ų11475.5 Ų75.574%0.7442%0.423SS*.THydrogen-bonded Turntrans-51.7-24-176.1-32.835.5000117.5S39S39-P339 WeakPolarHBondContact OG-CD 3.23Å
340F97.9Very high97.4Very high44 Ų4471.3 Ų71.319%0.19341%0.406CS..THydrogen-bonded Turntrans-106.17.9178.9-55.6-93.9000113.4M36 H338 P342 L343 Y344M36-F340 HydrophobicContact CB-CD1 4.24Å; M36-F340 HydrophobicContact CB-CD2 4.25Å; M36-F340 HydrophobicContact CB-CE1 4.49Å; M36-F340 HydrophobicContact CB-CG 4.11Å; M36-F340 HydrophobicContact CE-CD1 4.34Å; M36-F340 HydrophobicContact CG-CB 3.97Å; M36-F340 HydrophobicContact CG-CD1 4.44Å; M36-F340 HydrophobicContact CG-CD2 4.46Å; M36-F340 HydrophobicContact CG-CG 4.06Å; H338-F340 AromaticContact ND1-CD2 3.92Å; H338-F340 PolarHBondContact ND1-N 3.18Å; H338-F340 PolarHBondContact O-N 3.17Å; F340-P342 VanDerWaalsContact C-N 3.33Å; F340-P342 VanDerWaalsContact O-N 3.16Å; F340-L343 HydrophobicContact CB-CD1 4.23Å; F340-L343 HydrophobicContact CD1-CD1 4.02Å; F340-L343 WeakPolarHBondContact O-CB 3.18Å; F340-L343 PolarHBondContact O-N 3.37Å; F340-Y344 HydrophobicContact CB-CE2 4.33Å; F340-Y344 WeakPolarHBondContact O-CD2 3.02Å; F340-Y344 WeakPolarHBondContact O-CE2 3.48Å
341F98.3Very high97.5Very high58 Ų5867.9 Ų67.925%0.25438%0.379SS..G310 helixtrans-47.9-42.3-176.3178.6-97.3000114.8I335 H338 L343 Y344 F348I335-F341 HydrophobicContact CB-CE2 4.44Å; I335-F341 HydrophobicContact CG2-CD2 4.01Å; I335-F341 HydrophobicContact CG2-CE2 4.36Å; I335-F341 VanDerWaalsContact O-CE2 3.27Å; I335-F341 WeakPolarHBondContact O-CE2 3.43Å; H338-F341 WeakPolarHBondContact O-CB 3.47Å; H338-F341 PolarHBondContact O-N 3.28Å; F341-L343 PolarHBondContact O-N 2.96Å; F341-Y344 WeakPolarHBondContact O-CD2 3.47Å; F341-Y344 PolarHBondContact O-N 3.31Å; F341-Y344 VanDerWaalsContact O-N 3.12Å; F341-F348 HydrophobicContact CD1-CD1 4.31Å; F341-F348 HydrophobicContact CD1-CE1 4.2Å; F341-F348 HydrophobicContact CD2-CD1 4.42Å; F341-F348 AromaticContact CE1-CD1 3.71Å; F341-F348 HydrophobicContact CE1-CD1 3.71Å; F341-F348 AromaticContact CE1-CE1 3.71Å; F341-F348 HydrophobicContact CE1-CE1 3.71Å; F341-F348 HydrophobicContact CE2-CB 4.34Å; F341-F348 AromaticContact CE2-CD1 3.82Å; F341-F348 HydrophobicContact CE2-CD1 3.82Å; F341-F348 HydrophobicContact CE2-CG 4.39Å; F341-F348 HydrophobicContact CZ-CB 4.26Å; F341-F348 AromaticContact CZ-CD1 3.42Å; F341-F348 HydrophobicContact CZ-CD1 3.42Å; F341-F348 VanDerWaalsContact CZ-CD1 3.42Å; F341-F348 AromaticContact CZ-CE1 3.94Å; F341-F348 HydrophobicContact CZ-CE1 3.94Å; F341-F348 AromaticContact CZ-CG 3.95Å; F341-F348 HydrophobicContact CZ-CG 3.95Å
342P98Very high97.5Very high101 Ų10166.7 Ų66.766%0.65637%0.373SS*.G310 helixtrans-60.5-21.7179.1-25.736.3000115F340 Y344F340-P342 VanDerWaalsContact C-N 3.33Å; F340-P342 VanDerWaalsContact O-N 3.16Å; P342-Y344 VanDerWaalsContact C-N 3.25Å; P342-Y344 PolarHBondContact O-N 3.49Å
343L97.6Very high97.4Very high97 Ų9769 Ų6951%0.50838%0.377SS..G310 helixtrans-75.5-13.7-179.5-60.8-178.7000113.3M36 V313 F340 F341 G345M36-L343 HydrophobicContact CE-CD1 3.46Å; M36-L343 VanDerWaalsContact CE-CD1 3.46Å; V313-L343 HydrophobicContact CG2-CB 4.15Å; V313-L343 WeakPolarHBondContact CG2-O 3.47Å; F340-L343 HydrophobicContact CB-CD1 4.23Å; F340-L343 HydrophobicContact CD1-CD1 4.02Å; F340-L343 WeakPolarHBondContact O-CB 3.18Å; F340-L343 PolarHBondContact O-N 3.37Å; F341-L343 PolarHBondContact O-N 2.96Å; L343-G345 VanDerWaalsContact C-N 3.31Å
344Y98Very high97.1Very high2 Ų266 Ų661%0.00838%0.376CS..G310 helixtrans-88.92.1178.9-62.2-95.1000113M36 L40 V313 A316 K317 I335 H338 F340 F341 P342 D347 F348M36-Y344 HydrophobicContact CG-CE2 4.48Å; M36-Y344 WeakPolarHBondContact CG-OH 3.49Å; L40-Y344 HydrophobicContact CD1-CE1 4.49Å; L40-Y344 HydrophobicContact CD2-CE1 4.05Å; V313-Y344 HydrophobicContact CG1-CD1 3.69Å; V313-Y344 HydrophobicContact CG1-CE1 3.94Å; V313-Y344 HydrophobicContact CG1-CG 4.39Å; A316-Y344 WeakPolarHBondContact CB-OH 3.43Å; K317-Y344 HydrophobicContact CG-CD1 4.23Å; K317-Y344 HydrophobicContact CG-CE1 4Å; I335-Y344 HydrophobicContact CD1-CD1 3.79Å; I335-Y344 HydrophobicContact CD1-CE1 4.03Å; I335-Y344 HydrophobicContact CD1-CG 4.47Å; I335-Y344 HydrophobicContact CG1-CD1 3.92Å; I335-Y344 HydrophobicContact CG1-CG 4.16Å; I335-Y344 HydrophobicContact CG2-CD1 4.21Å; I335-Y344 HydrophobicContact CG2-CD2 4.04Å; I335-Y344 HydrophobicContact CG2-CE2 4.39Å; I335-Y344 HydrophobicContact CG2-CG 3.95Å; H338-Y344 AromaticContact CE1-CE2 3.65Å; H338-Y344 AromaticContact NE2-CD2 3.92Å; H338-Y344 AromaticContact NE2-CE2 3.07Å; H338-Y344 WeakPolarHBondContact NE2-CE2 3.07Å; H338-Y344 AromaticContact NE2-CZ 3.58Å; F340-Y344 HydrophobicContact CB-CE2 4.33Å; F340-Y344 WeakPolarHBondContact O-CD2 3.02Å; F340-Y344 WeakPolarHBondContact O-CE2 3.48Å; F341-Y344 WeakPolarHBondContact O-CD2 3.47Å; F341-Y344 PolarHBondContact O-N 3.31Å; F341-Y344 VanDerWaalsContact O-N 3.12Å; P342-Y344 VanDerWaalsContact C-N 3.25Å; P342-Y344 PolarHBondContact O-N 3.49Å; Y344-D347 VanDerWaalsContact O-OD1 3.07Å; Y344-F348 WeakPolarHBondContact O-CA 3.43Å; Y344-F348 PolarHBondContact O-N 2.99Å
345G95.2Very high96.8Very high35 Ų3562.1 Ų62.136%0.36136%0.362SS..THydrogen-bonded Turntrans-67.9158.9175.900000112.9L343L343-G345 VanDerWaalsContact C-N 3.31Å
346P96Very high96.5Very high125 Ų12567.6 Ų67.681%0.81240%0.401SS*.THydrogen-bonded Turncis-88.9-9.56.735-36.2000114.6F348P346-F348 VanDerWaalsContact O-CD2 3.31Å; P346-F348 WeakPolarHBondContact O-CD2 3.39Å; P346-F348 WeakPolarHBondContact O-CE2 3.34Å
347D95.9Very high96.3Very high85 Ų8567.9 Ų67.946%0.45540%0.401SS..THydrogen-bonded Turntrans-90.8-30.6-170.260.35000113.7K317 Y344 V349K317-D347 IonicContact NZ-OD1 2.8Å; Y344-D347 VanDerWaalsContact O-OD1 3.07Å; D347-V349 HydrophobicContact CB-CG2 4.03Å; D347-V349 PolarHBondContact O-N 3.21Å
348F97.7Very high96.2Very high69 Ų6964.7 Ų64.730%0.30340%0.395SS..  trans56.530.9-179.3-51.3-84.3000113.7I335 F341 Y344 P346I335-F348 WeakPolarHBondContact CB-O 3.42Å; I335-F348 WeakPolarHBondContact CG1-O 3.08Å; I335-F348 PolarHBondContact N-O 2.88Å; F341-F348 HydrophobicContact CD1-CD1 4.31Å; F341-F348 HydrophobicContact CD1-CE1 4.2Å; F341-F348 HydrophobicContact CD2-CD1 4.42Å; F341-F348 AromaticContact CE1-CD1 3.71Å; F341-F348 HydrophobicContact CE1-CD1 3.71Å; F341-F348 AromaticContact CE1-CE1 3.71Å; F341-F348 HydrophobicContact CE1-CE1 3.71Å; F341-F348 HydrophobicContact CE2-CB 4.34Å; F341-F348 AromaticContact CE2-CD1 3.82Å; F341-F348 HydrophobicContact CE2-CD1 3.82Å; F341-F348 HydrophobicContact CE2-CG 4.39Å; F341-F348 HydrophobicContact CZ-CB 4.26Å; F341-F348 AromaticContact CZ-CD1 3.42Å; F341-F348 HydrophobicContact CZ-CD1 3.42Å; F341-F348 VanDerWaalsContact CZ-CD1 3.42Å; F341-F348 AromaticContact CZ-CE1 3.94Å; F341-F348 HydrophobicContact CZ-CE1 3.94Å; F341-F348 AromaticContact CZ-CG 3.95Å; F341-F348 HydrophobicContact CZ-CG 3.95Å; Y344-F348 WeakPolarHBondContact O-CA 3.43Å; Y344-F348 PolarHBondContact O-N 2.99Å; P346-F348 VanDerWaalsContact O-CD2 3.31Å; P346-F348 WeakPolarHBondContact O-CD2 3.39Å; P346-F348 WeakPolarHBondContact O-CE2 3.34Å
349V98Very high96.2Very high29 Ų2966.4 Ų66.418%0.17641%0.405CS..BIsolated β-bridgetrans-112.4152.2177.6-60.60000112.3K317 E333 D347 T351K317-V349 WeakPolarHBondContact CE-O 3.4Å; K317-V349 PolarHBondContact NZ-O 3.1Å; E333-V349 HydrophobicContact CG-CB 3.76Å; E333-V349 HydrophobicContact CG-CG1 3.87Å; E333-V349 CarbonylContact O-C 3.51Å; E333-V349 WeakPolarHBondContact O-CA 3.43Å; D347-V349 HydrophobicContact CB-CG2 4.03Å; D347-V349 PolarHBondContact O-N 3.21Å; V349-T351 VanDerWaalsContact C-N 3.33Å
350L98Very high96.2Very high10 Ų1063.2 Ų63.25%0.05239%0.388CS..SBendtrans-72-27.8178.2-171.164000113Y44 K317 Q321 L331 E333 I335Y44-L350 HydrophobicContact CE2-CD1 4.1Å; K317-L350 HydrophobicContact CB-CD1 4.04Å; K317-L350 HydrophobicContact CG-CD1 4.18Å; Q321-L350 HydrophobicContact CG-CD1 4.2Å; Q321-L350 HydrophobicContact CG-CD2 3.6Å; Q321-L350 HydrophobicContact CG-CG 3.89Å; Q321-L350 PolarHBondContact NE2-O 3.25Å; L331-L350 HydrophobicContact CB-CD2 3.71Å; L331-L350 HydrophobicContact CD1-CD2 3.6Å; L331-L350 HydrophobicContact CG-CD2 4.28Å; E333-L350 WeakPolarHBondContact O-CB 3.42Å; E333-L350 PolarHBondContact O-N 3.1Å; I335-L350 HydrophobicContact CD1-CB 4.24Å; I335-L350 HydrophobicContact CD1-CD1 4.01Å
351T97Very high96.2Very high52 Ų5261.3 Ų61.332%0.31938%0.38SS..  trans-62.2136.9-179.5-57.50000111E333 V349E333-T351 PolarHBondContact OE1-OG1 3.09Å; V349-T351 VanDerWaalsContact C-N 3.33Å
352I96.9Very high96.2Very high17 Ų1761.4 Ų61.49%0.08739%0.388CS..  trans-111.6116.2169.4-55.3179.6000107L273 T274 T284 P285 N314 K317L273-I352 HydrophobicContact CD1-CD1 4.23Å; T274-I352 HydrophobicContact CG2-CG2 3.46Å; T274-I352 VanDerWaalsContact CG2-CG2 3.46Å; T284-I352 WeakPolarHBondContact CG2-O 3.27Å; P285-I352 HydrophobicContact CG-CB 4.41Å; P285-I352 HydrophobicContact CG-CD1 3.7Å; P285-I352 HydrophobicContact CG-CG1 4.08Å; N314-I352 HydrophobicContact CB-CD1 3.73Å; K317-I352 HydrophobicContact CB-CD1 4.14Å; K317-I352 HydrophobicContact CB-CG1 4.39Å; K317-I352 HydrophobicContact CD-CD1 4.35Å; K317-I352 HydrophobicContact CD-CG1 3.93Å
353Q94.1Very high96.1Very high149 Ų14959.2 Ų59.270%0.69638%0.379SS*.  trans-75.3139.5178.7-66.3-67.6-2700110.7T274T274-Q353 WeakPolarHBondContact CG2-O 3.4Å
354G92.3Very high96.1Very high46 Ų4661.8 Ų61.847%0.47439%0.388SS..  trans-56.5139.6173.700000111.8
355G91.7Very high96.1Very high32 Ų3264 Ų6433%0.3340%0.396SS..  trans-83-179.2178.400000113.5T274 N282T274-G355 WeakPolarHBondContact OG1-CA 3.33Å; T274-G355 PolarHBondContact OG1-N 2.95Å; T274-G355 VanDerWaalsContact OG1-N 3.11Å; N282-G355 PolarHBondContact ND2-O 3.4Å; N282-G355 WeakPolarHBondContact OD1-CA 3.43Å; N282-G355 PolarHBondContact OD1-N 3.03Å
356S92.6Very high96.2Very high123 Ų12362.8 Ų62.886%0.8638%0.382SS*.  trans-93.86.7-179.556.60000114.4P358S356-P358 WeakPolarHBondContact O-CD 3.44Å
357L93.7Very high96.2Very high41 Ų4164 Ų6422%0.21537%0.37CS..  trans-57.5122.2-178.6-173.363.1000110.5R237 Q279 N282R237-L357 HydrophobicContact CG-CD1 4.28Å; R237-L357 HydrophobicContact CG-CD2 3.98Å; R237-L357 HydrophobicContact CG-CG 4.37Å; Q279-L357 WeakPolarHBondContact O-CD2 3.34Å; N282-L357 HydrophobicContact CB-CB 4.34Å
358P95.7Very high96.3Very high107 Ų10761.5 Ų61.570%0.69536%0.364SS*.  trans-60.5140.1177.5-2535.2000111.6G238 S356G238-P358 WeakPolarHBondContact CA-O 3.36Å; S356-P358 WeakPolarHBondContact O-CD 3.44Å
359N97.5Very high96.2Very high58 Ų5858.9 Ų58.931%0.3135%0.353SS..  trans-96.1112.3-176.4-175-1.8000111.4G238 Q243 N361G238-N359 VanDerWaalsContact O-CB 3.24Å; G238-N359 WeakPolarHBondContact O-CB 3.49Å; G238-N359 PolarHBondContact O-OD1 3.5Å; Q243-N359 PolarHBondContact OE1-ND2 3.48Å; N359-N361 VanDerWaalsContact C-N 3.34Å; N359-N361 VanDerWaalsContact OD1-CB 3.31Å; N359-N361 WeakPolarHBondContact OD1-CB 3.25Å; N359-N361 PolarHBondContact OD1-N 3.34Å; N359-N361 PolarHBondContact OD1-ND2 2.69Å
360A97.8Very high96.1Very high47 Ų4757.9 Ų57.939%0.38835%0.347SS..  trans-87.20.8-18000000113.9R236 R237 S362R236-A360 HydrophobicContact CB-CB 3.8Å; R236-A360 WeakPolarHBondContact CD-O 3.19Å; R237-A360 PolarHBondContact O-N 3.15Å; A360-S362 PolarHBondContact O-N 3.37Å
361N98.1Very high96Very high4 Ų465.6 Ų65.62%0.02138%0.377CS..  trans-89.885.6-179.8-59.7-85.2000110.8R236 L239 Q243 N359 L366R236-N361 PolarHBondContact N-OD1 3.02Å; R236-N361 PolarHBondContact O-ND2 3.37Å; L239-N361 HydrophobicContact CD1-CB 3.97Å; L239-N361 PolarHBondContact N-ND2 2.71Å; Q243-N361 PolarHBondContact NE2-O 2.96Å; N359-N361 VanDerWaalsContact C-N 3.34Å; N359-N361 VanDerWaalsContact OD1-CB 3.31Å; N359-N361 WeakPolarHBondContact OD1-CB 3.25Å; N359-N361 PolarHBondContact OD1-N 3.34Å; N359-N361 PolarHBondContact OD1-ND2 2.69Å; N361-L366 HydrophobicContact CB-CD1 4.1Å; N361-L366 HydrophobicContact CB-CD2 3.98Å; N361-L366 HydrophobicContact CB-CG 4.07Å
362S97.6Very high95.9Very high61 Ų6166.5 Ų66.543%0.42738%0.379SS..  trans-64.7149.7173.672.60000110.9A360 E364 Y365 L366A360-S362 PolarHBondContact O-N 3.37Å; S362-E364 PolarHBondContact O-N 3.36Å; S362-Y365 WeakPolarHBondContact O-CB 3.39Å; S362-Y365 PolarHBondContact O-N 2.98Å; S362-Y365 WeakPolarHBondContact OG-CB 3.32Å; S362-Y365 PolarHBondContact OG-N 3.26Å; S362-Y365 VanDerWaalsContact OG-N 3.16Å; S362-L366 PolarHBondContact O-N 3.38Å
363A96.7Very high95.7Very high55 Ų5565.7 Ų65.746%0.45538%0.375SS..Hα-helixtrans-60.2-30.6177.700000112.4R367A363-R367 WeakPolarHBondContact O-CB 3.48Å; A363-R367 VanDerWaalsContact O-CG 3.31Å; A363-R367 WeakPolarHBondContact O-CG 3.39Å; A363-R367 PolarHBondContact O-N 2.84Å; A363-R367 VanDerWaalsContact O-N 3.11Å
364E97.9Very high95.6Very high151 Ų15159.7 Ų59.771%0.70635%0.351SS*.Hα-helixtrans-65.6-46.4173-176.3178.3-175.800112S362 R367 G368S362-E364 PolarHBondContact O-N 3.36Å; E364-R367 PolarHBondContact O-N 2.94Å; E364-G368 PolarHBondContact O-N 2.79Å
365Y97.9Very high95.6Very high47 Ų4760.3 Ų60.318%0.18435%0.348CS..Hα-helixtrans-58.5-50.4177.1173.5-102.8000111.5P234 R236 S362 R367 G368 I369P234-Y365 PolarHBondContact O-OH 2.86Å; R236-Y365 HydrophobicContact CG-CD1 4.49Å; R236-Y365 HydrophobicContact CG-CE1 3.93Å; S362-Y365 WeakPolarHBondContact O-CB 3.39Å; S362-Y365 PolarHBondContact O-N 2.98Å; S362-Y365 WeakPolarHBondContact OG-CB 3.32Å; S362-Y365 PolarHBondContact OG-N 3.26Å; S362-Y365 VanDerWaalsContact OG-N 3.16Å; Y365-R367 PolarHBondContact O-N 3.31Å; Y365-G368 PolarHBondContact O-N 2.87Å; Y365-G368 VanDerWaalsContact O-N 3.11Å; Y365-I369 HydrophobicContact CE1-CG1 4.13Å; Y365-I369 HydrophobicContact CE2-CD1 4.24Å; Y365-I369 HydrophobicContact CE2-CG1 4.04Å; Y365-I369 PolarHBondContact O-N 2.72Å
366L97.5Very high95.6Very high11 Ų1159.7 Ų59.76%0.05834%0.335CS..Hα-helixtrans-61.3-43.8-179.4-65.4-178.9000112.1L235 Q243 I247 N361 S362 G368 I369 I370L235-L366 HydrophobicContact CD2-CD2 3.82Å; Q243-L366 HydrophobicContact CB-CD1 3.93Å; Q243-L366 HydrophobicContact CG-CD1 3.99Å; I247-L366 HydrophobicContact CD1-CD1 4.07Å; I247-L366 HydrophobicContact CD1-CD2 3.65Å; I247-L366 HydrophobicContact CD1-CG 4.37Å; I247-L366 HydrophobicContact CG1-CD2 4.41Å; N361-L366 HydrophobicContact CB-CD1 4.1Å; N361-L366 HydrophobicContact CB-CD2 3.98Å; N361-L366 HydrophobicContact CB-CG 4.07Å; S362-L366 PolarHBondContact O-N 3.38Å; L366-G368 VanDerWaalsContact C-N 3.3Å; L366-G368 PolarHBondContact O-N 2.99Å; L366-I369 PolarHBondContact O-N 3.11Å; L366-I370 VanDerWaalsContact O-CG1 3.28Å; L366-I370 WeakPolarHBondContact O-CG1 3.39Å; L366-I370 PolarHBondContact O-N 3.39Å
367R96.4Very high95.3Very high150 Ų15054.2 Ų54.257%0.56630%0.296SS*.Hα-helixtrans-61.1-38.9174.5-76.8-171.3-60-94.91.4112.3A363 E364 Y365 Y371A363-R367 WeakPolarHBondContact O-CB 3.48Å; A363-R367 VanDerWaalsContact O-CG 3.31Å; A363-R367 WeakPolarHBondContact O-CG 3.39Å; A363-R367 PolarHBondContact O-N 2.84Å; A363-R367 VanDerWaalsContact O-N 3.11Å; E364-R367 PolarHBondContact O-N 2.94Å; Y365-R367 PolarHBondContact O-N 3.31Å; R367-Y371 VanDerWaalsContact O-CB 3.28Å; R367-Y371 WeakPolarHBondContact O-CB 3.43Å; R367-Y371 PolarHBondContact O-N 3.18Å
368G97.1Very high94.9Very high32 Ų3256.2 Ų56.233%0.3331%0.311SS..Hα-helixtrans-60.1-50176.400000112.2E364 Y365 L366 Y371 I372E364-G368 PolarHBondContact O-N 2.79Å; Y365-G368 PolarHBondContact O-N 2.87Å; Y365-G368 VanDerWaalsContact O-N 3.11Å; L366-G368 VanDerWaalsContact C-N 3.3Å; L366-G368 PolarHBondContact O-N 2.99Å; G368-Y371 PolarHBondContact O-N 3.24Å; G368-I372 WeakPolarHBondContact O-CG1 3.08Å; G368-I372 PolarHBondContact O-N 3.27Å
369I96.3Very high94.2Very high14 Ų1455.5 Ų55.57%0.07230%0.299CS..Hα-helixtrans-60.7-48.8177.4-66.2-58.7000111.2V218 V233 P234 Y365 L366 Y371 I372 I373V218-I369 HydrophobicContact CB-CD1 4.06Å; V218-I369 HydrophobicContact CG1-CD1 4.14Å; V218-I369 HydrophobicContact CG2-CD1 4.3Å; V218-I369 HydrophobicContact CG2-CG2 4.45Å; V233-I369 HydrophobicContact CG1-CG2 4.1Å; P234-I369 HydrophobicContact CG-CD1 3.9Å; Y365-I369 HydrophobicContact CE1-CG1 4.13Å; Y365-I369 HydrophobicContact CE2-CD1 4.24Å; Y365-I369 HydrophobicContact CE2-CG1 4.04Å; Y365-I369 PolarHBondContact O-N 2.72Å; L366-I369 PolarHBondContact O-N 3.11Å; I369-Y371 VanDerWaalsContact C-N 3.29Å; I369-Y371 PolarHBondContact O-N 3.19Å; I369-I372 PolarHBondContact O-N 3.22Å; I369-I373 HydrophobicContact CG2-CD1 3.61Å; I369-I373 HydrophobicContact CG2-CG1 4.46Å; I369-I373 WeakPolarHBondContact O-CD1 3.47Å; I369-I373 WeakPolarHBondContact O-CG1 3.33Å; I369-I373 PolarHBondContact O-N 3.08Å
370I95.2Very high93.3Very high9 Ų952.8 Ų52.85%0.04628%0.284CS..Hα-helixtrans-60.3-40.6179-66.7167.4000111.1I247 Q250 L366 I373 A374I247-I370 HydrophobicContact CB-CD1 4.44Å; I247-I370 HydrophobicContact CG1-CD1 4.11Å; I247-I370 HydrophobicContact CG2-CD1 4.37Å; I247-I370 HydrophobicContact CG2-CG1 4.3Å; Q250-I370 HydrophobicContact CB-CD1 4.44Å; Q250-I370 HydrophobicContact CB-CG2 4.25Å; L366-I370 VanDerWaalsContact O-CG1 3.28Å; L366-I370 WeakPolarHBondContact O-CG1 3.39Å; L366-I370 PolarHBondContact O-N 3.39Å; I370-I373 PolarHBondContact O-N 3.38Å; I370-A374 WeakPolarHBondContact O-CB 3.44Å; I370-A374 PolarHBondContact O-N 3.15Å
371Y95.3Very high91.7Very high172 Ų17254.8 Ų54.868%0.67529%0.291SS*.Hα-helixtrans-62-47.8177.4175.1-96.8000111.8R367 G368 I369 I373 A374 S375R367-Y371 VanDerWaalsContact O-CB 3.28Å; R367-Y371 WeakPolarHBondContact O-CB 3.43Å; R367-Y371 PolarHBondContact O-N 3.18Å; G368-Y371 PolarHBondContact O-N 3.24Å; I369-Y371 VanDerWaalsContact C-N 3.29Å; I369-Y371 PolarHBondContact O-N 3.19Å; Y371-I373 PolarHBondContact O-N 2.93Å; Y371-A374 PolarHBondContact O-N 3.4Å; Y371-S375 WeakPolarHBondContact O-CB 3.34Å; Y371-S375 PolarHBondContact O-N 2.53Å
372I95.1Very high89.6Confident70 Ų7061.4 Ų61.436%0.35933%0.327SS..Hα-helixtrans-58.7-49.5178.1-66.1165.5000109.8V218 G368 I369 A374 S375V218-I372 HydrophobicContact CG1-CD1 4.03Å; V218-I372 HydrophobicContact CG1-CG2 4.2Å; V218-I372 HydrophobicContact CG2-CB 3.97Å; V218-I372 HydrophobicContact CG2-CG2 3.58Å; G368-I372 WeakPolarHBondContact O-CG1 3.08Å; G368-I372 PolarHBondContact O-N 3.27Å; I369-I372 PolarHBondContact O-N 3.22Å; I372-A374 PolarHBondContact O-N 2.81Å; I372-S375 PolarHBondContact O-N 3.12Å; I372-S375 PolarHBondContact O-OG 3.07Å
373I94.4Very high87.4Confident1 Ų162.9 Ų62.91%0.00533%0.329CS..Hα-helixtrans-57.8-51.3178.7-66.2161.1000110.8V218 V231 V233 I251 I369 I370 Y371 S375 R376 F377V218-I373 HydrophobicContact CG2-CG1 3.94Å; V231-I373 HydrophobicContact CG1-CG2 3.72Å; V233-I373 HydrophobicContact CB-CD1 4.32Å; V233-I373 HydrophobicContact CG1-CD1 4.21Å; V233-I373 HydrophobicContact CG2-CD1 3.83Å; I251-I373 HydrophobicContact CD1-CD1 3.89Å; I369-I373 HydrophobicContact CG2-CD1 3.61Å; I369-I373 HydrophobicContact CG2-CG1 4.46Å; I369-I373 WeakPolarHBondContact O-CD1 3.47Å; I369-I373 WeakPolarHBondContact O-CG1 3.33Å; I369-I373 PolarHBondContact O-N 3.08Å; I370-I373 PolarHBondContact O-N 3.38Å; Y371-I373 PolarHBondContact O-N 2.93Å; I373-S375 VanDerWaalsContact C-N 3.29Å; I373-S375 PolarHBondContact O-N 3.42Å; I373-R376 PolarHBondContact O-N 2.97Å; I373-F377 HydrophobicContact CG2-CE1 3.96Å; I373-F377 HydrophobicContact CG2-CE2 4.03Å; I373-F377 HydrophobicContact CG2-CZ 3.48Å; I373-F377 VanDerWaalsContact CG2-CZ 3.48Å
374A91.2Very high85.1Confident23 Ų2364.8 Ų64.819%0.1933%0.327CS..Hα-helixtrans-62.1-35.4-177.200000113.2I370 Y371 I372 R376 F377 P378I370-A374 WeakPolarHBondContact O-CB 3.44Å; I370-A374 PolarHBondContact O-N 3.15Å; Y371-A374 PolarHBondContact O-N 3.4Å; I372-A374 PolarHBondContact O-N 2.81Å; A374-R376 PolarHBondContact O-N 2.91Å; A374-F377 PolarHBondContact O-N 2.95Å; A374-P378 WeakPolarHBondContact O-CD 3.46Å
375S92.3Very high82.1Confident59 Ų5962.5 Ų62.541%0.41333%0.325SS..Hα-helixtrans-64.7-19.7-179.174.90000113.5Y371 I372 I373Y371-S375 WeakPolarHBondContact O-CB 3.34Å; Y371-S375 PolarHBondContact O-N 2.53Å; I372-S375 PolarHBondContact O-N 3.12Å; I372-S375 PolarHBondContact O-OG 3.07Å; I373-S375 VanDerWaalsContact C-N 3.29Å; I373-S375 PolarHBondContact O-N 3.42Å
376R90.6Very high79.1Confident18 Ų1866.1 Ų66.17%0.06836%0.358CS..Hα-helixtrans-86.1-29.7179.2-61.6179.5-63.7-165.10.5113V218 I373 A374 P378 Q379V218-R376 PolarHBondContact O-NH1 3.4Å; I373-R376 PolarHBondContact O-N 2.97Å; A374-R376 PolarHBondContact O-N 2.91Å; R376-P378 VanDerWaalsContact C-CD 3.44Å; R376-Q379 VanDerWaalsContact O-CB 3.29Å; R376-Q379 WeakPolarHBondContact O-CB 3.35Å; R376-Q379 PolarHBondContact O-N 3.12Å
377F88Confident76.1Confident9 Ų976.5 Ų76.54%0.03941%0.413CS..THydrogen-bonded Turntrans-56.8-36.2-174.6-70-18.4000115.6V231 R254 L255 V258 I373 A374 Q379 L380V231-F377 HydrophobicContact CG1-CZ 4.45Å; V231-F377 HydrophobicContact CG2-CE1 4.03Å; R254-F377 HydrophobicContact CB-CD2 3.55Å; R254-F377 HydrophobicContact CB-CE2 3.46Å; R254-F377 VanDerWaalsContact CB-CE2 3.46Å; R254-F377 HydrophobicContact CG-CD2 4.3Å; R254-F377 HydrophobicContact CG-CE2 4.32Å; L255-F377 HydrophobicContact CD2-CE1 3.91Å; L255-F377 HydrophobicContact CD2-CZ 3.62Å; L255-F377 HydrophobicContact CG-CZ 4.33Å; V258-F377 HydrophobicContact CG1-CB 3.91Å; V258-F377 HydrophobicContact CG1-CG 4.49Å; V258-F377 HydrophobicContact CG2-CB 4.39Å; V258-F377 HydrophobicContact CG2-CD1 4.17Å; V258-F377 HydrophobicContact CG2-CG 4.23Å; I373-F377 HydrophobicContact CG2-CE1 3.96Å; I373-F377 HydrophobicContact CG2-CE2 4.03Å; I373-F377 HydrophobicContact CG2-CZ 3.48Å; I373-F377 VanDerWaalsContact CG2-CZ 3.48Å; A374-F377 PolarHBondContact O-N 2.95Å; F377-Q379 PolarHBondContact O-N 3.34Å; F377-Q379 VanDerWaalsContact O-N 3.16Å; F377-L380 HydrophobicContact CD1-CD1 4.15Å; F377-L380 WeakPolarHBondContact O-CB 3.31Å; F377-L380 PolarHBondContact O-N 3.49Å
378P84.3Confident75.1Confident82 Ų8272.8 Ų72.853%0.53241%0.405SS..Hα-helixtrans-55.9-30.9173.4-2836.5000113.8A374 R376 L380 V381A374-P378 WeakPolarHBondContact O-CD 3.46Å; R376-P378 VanDerWaalsContact C-CD 3.44Å; P378-L380 PolarHBondContact O-N 2.8Å; P378-V381 PolarHBondContact O-N 3.47Å
379Q81.3Confident73.9Confident93 Ų9374.9 Ų74.944%0.43541%0.409SS..Hα-helixtrans-69.9-12.9-179.8-56.5174.736.300113.3N228 R376 F377N228-Q379 PolarHBondContact ND2-OE1 3.13Å; R376-Q379 VanDerWaalsContact O-CB 3.29Å; R376-Q379 WeakPolarHBondContact O-CB 3.35Å; R376-Q379 PolarHBondContact O-N 3.12Å; F377-Q379 PolarHBondContact O-N 3.34Å; F377-Q379 VanDerWaalsContact O-N 3.16Å
380L78.6Confident72.7Confident1 Ų178.3 Ų78.31%0.00543%0.428CS..Hα-helixtrans-88.2-24.5177.6-64.8173.4000112.6M200 N228 Y229 V258 F377 P378 D382M200-L380 HydrophobicContact CE-CD1 3.69Å; N228-L380 HydrophobicContact CB-CD1 4.49Å; N228-L380 HydrophobicContact CB-CD2 3.67Å; N228-L380 HydrophobicContact CB-CG 4.06Å; Y229-L380 HydrophobicContact CD1-CD2 4.42Å; Y229-L380 HydrophobicContact CD2-CD2 3.77Å; Y229-L380 HydrophobicContact CE1-CD2 4.09Å; Y229-L380 HydrophobicContact CE2-CD2 3.39Å; Y229-L380 HydrophobicContact CG-CD2 4.27Å; V258-L380 HydrophobicContact CB-CB 4.2Å; V258-L380 HydrophobicContact CB-CD1 4.26Å; V258-L380 HydrophobicContact CG2-CD1 3.7Å; F377-L380 HydrophobicContact CD1-CD1 4.15Å; F377-L380 WeakPolarHBondContact O-CB 3.31Å; F377-L380 PolarHBondContact O-N 3.49Å; P378-L380 PolarHBondContact O-N 2.8Å; L380-D382 VanDerWaalsContact C-N 3.32Å; L380-D382 PolarHBondContact O-N 3.22Å
381V64.9Low71.3Confident88 Ų8882.4 Ų82.453%0.53345%0.451SS..Hα-helixtrans-71.5-30.7-176.1-1770000111.2V258 P378 I383V258-V381 HydrophobicContact CG1-CG2 4.03Å; P378-V381 PolarHBondContact O-N 3.47Å; V381-I383 VanDerWaalsContact C-N 3.32Å; V381-I383 PolarHBondContact O-N 3.37Å
382D52.4Low69.8Low143 Ų14376.8 Ų76.877%0.76544%0.437SS*.THydrogen-bonded Turntrans-81.1-2.8-174.4-69.8-30.5000114.8L380L380-D382 VanDerWaalsContact C-N 3.32Å; L380-D382 PolarHBondContact O-N 3.22Å
383I52.8Low68.2Low92 Ų9277.3 Ų77.347%0.47244%0.442SS..THydrogen-bonded Turntrans-95.1-16.1-171.7-57.6178.9000112.8V381 P385V381-I383 VanDerWaalsContact C-N 3.32Å; V381-I383 PolarHBondContact O-N 3.37Å; I383-P385 WeakPolarHBondContact O-CD 3.17Å
384F47Very low66.3Low96 Ų9682.7 Ų82.742%0.42147%0.473SS..  trans-116.794.6178.7-64.5-70.1000111Y229 S386Y229-F384 VanDerWaalsContact OH-CE2 3.3Å; Y229-F384 WeakPolarHBondContact OH-CE2 3.38Å; F384-S386 PolarHBondContact O-N 3.21Å
385P35.6Very low64.4Low102 Ų10287.3 Ų87.366%0.66250%0.495SS*.  trans-60.7126.9161.727.3-30.3000106.9I383 N387I383-P385 WeakPolarHBondContact O-CD 3.17Å; P385-N387 PolarHBondContact O-N 3.26Å
386S35.9Very low62Low124 Ų12489.7 Ų89.787%0.86750%0.502SS*.  trans-49104.7167.548.20000108.8F384F384-S386 PolarHBondContact O-N 3.21Å
387N33Very low59.4Low228 Ų22896.2 Ų96.2100%1.21954%0.541SS*.  trans-77.50170-83.7-19.8000110.6P385P385-N387 PolarHBondContact O-N 3.26Å

Retrieved 387 of 387 residues in 452.8 ms (Link to these results)