A0A077ZKV3_TRITR Loading...

Protein SMG5

AlphaFold DB , UniProt , Accession A0A077ZKV3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 646 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M85.5Confident80.9Confident183 Ų18376.2 Ų76.290%0.90142%0.422SS*.  0-68.60-173-179.8-89.700110.5E3 S4 I5M1-E3 PolarHBondContact O-N 3.44Å; M1-S4 WeakPolarHBondContact O-CB 3.25Å; M1-S4 PolarHBondContact O-N 3.32Å; M1-I5 HydrophobicContact CG-CD1 4.44Å; M1-I5 PolarHBondContact O-N 2.86Å
2Y88Confident79.8Confident72 Ų7277.8 Ų77.828%0.28244%0.441SS..Hα-helixtrans-53.8-46.4-179.3-63.1-64.4000114.1S4 I5 I6 A17 L20 M21Y2-S4 VanDerWaalsContact C-N 3.26Å; Y2-S4 PolarHBondContact O-N 2.97Å; Y2-I5 WeakPolarHBondContact O-CA 3.38Å; Y2-I5 WeakPolarHBondContact O-CB 3.07Å; Y2-I5 PolarHBondContact O-N 3.42Å; Y2-I6 WeakPolarHBondContact O-CG1 3.48Å; Y2-I6 PolarHBondContact O-N 3.24Å; Y2-A17 HydrophobicContact CD1-CB 4.14Å; Y2-A17 WeakPolarHBondContact CD1-O 3.37Å; Y2-L20 HydrophobicContact CE1-CB 4.15Å; Y2-M21 HydrophobicContact CD1-CB 4.34Å; Y2-M21 HydrophobicContact CD2-CB 3.66Å; Y2-M21 HydrophobicContact CD2-CG 3.89Å; Y2-M21 HydrophobicContact CE2-CB 4.19Å; Y2-M21 HydrophobicContact CG-CB 3.75Å; Y2-M21 HydrophobicContact CG-CG 4.25Å
3E87.2Confident80.1Confident50 Ų5079.2 Ų79.223%0.23445%0.445CS..Hα-helixtrans-55-39.6176.6-175.4172.6159.400113.4M1 I5 I6 L7 Y58 L62 K65M1-E3 PolarHBondContact O-N 3.44Å; E3-I5 VanDerWaalsContact C-N 3.29Å; E3-I5 PolarHBondContact O-N 2.78Å; E3-I6 PolarHBondContact O-N 3.03Å; E3-L7 HydrophobicContact CG-CD1 3.81Å; E3-L7 HydrophobicContact CG-CG 4.35Å; E3-L7 WeakPolarHBondContact O-CB 3.42Å; E3-L7 WeakPolarHBondContact O-CG 3.21Å; E3-L7 PolarHBondContact O-N 3.21Å; E3-Y58 WeakPolarHBondContact OE2-CE2 3.47Å; E3-L62 HydrophobicContact CG-CD1 4.02Å; E3-K65 IonicContact OE1-NZ 2.63Å; E3-K65 PolarHBondContact OE1-NZ 3.19Å
4S86.8Confident80.5Confident90 Ų9073.6 Ų73.663%0.62941%0.414SS*.Hα-helixtrans-67.1-32.2178.4-51.50000112.1M1 Y2 G8M1-S4 WeakPolarHBondContact O-CB 3.25Å; M1-S4 PolarHBondContact O-N 3.32Å; Y2-S4 VanDerWaalsContact C-N 3.26Å; Y2-S4 PolarHBondContact O-N 2.97Å; S4-G8 WeakPolarHBondContact O-CA 3.16Å; S4-G8 PolarHBondContact O-N 2.96Å
5I87.5Confident80.7Confident58 Ų5873 Ų7330%0.29741%0.408SS..Hα-helixtrans-71.9-47.5174.7-60.3169.9000109.4M1 Y2 E3 L7 G8 D9 L13 A17M1-I5 HydrophobicContact CG-CD1 4.44Å; M1-I5 PolarHBondContact O-N 2.86Å; Y2-I5 WeakPolarHBondContact O-CA 3.38Å; Y2-I5 WeakPolarHBondContact O-CB 3.07Å; Y2-I5 PolarHBondContact O-N 3.42Å; E3-I5 VanDerWaalsContact C-N 3.29Å; E3-I5 PolarHBondContact O-N 2.78Å; I5-L7 VanDerWaalsContact C-N 3.31Å; I5-L7 PolarHBondContact O-N 3.45Å; I5-G8 PolarHBondContact O-N 3.4Å; I5-D9 PolarHBondContact O-N 3.29Å; I5-L13 HydrophobicContact CG2-CB 3.76Å; I5-A17 HydrophobicContact CB-CB 4.08Å; I5-A17 HydrophobicContact CG2-CB 3.76Å
6I86.5Confident81.2Confident1 Ų172.5 Ų72.51%0.00540%0.404CS..Hα-helixtrans-58.3-42.9-179.6-66.2166.3000111.5Y2 E3 A17 E18 M21 L62 V66 M102Y2-I6 WeakPolarHBondContact O-CG1 3.48Å; Y2-I6 PolarHBondContact O-N 3.24Å; E3-I6 PolarHBondContact O-N 3.03Å; I6-A17 HydrophobicContact CG1-CB 4.13Å; I6-E18 HydrophobicContact CD1-CB 3.85Å; I6-E18 HydrophobicContact CD1-CG 4.21Å; I6-E18 HydrophobicContact CG1-CB 4.35Å; I6-M21 HydrophobicContact CD1-CE 4.38Å; I6-L62 HydrophobicContact CD1-CD2 4.16Å; I6-L62 HydrophobicContact CG2-CD1 4.42Å; I6-V66 HydrophobicContact CG2-CG2 4.02Å; I6-M102 HydrophobicContact CG2-CE 4.29Å; I6-M102 HydrophobicContact CG2-SD 4.35Å
7L86Confident81.8Confident62 Ų6268.6 Ų68.633%0.32538%0.384SS..Hα-helixtrans-86.7-16.5-179-61.2176.2000113.6E3 I5 L62 K65 V66E3-L7 HydrophobicContact CG-CD1 3.81Å; E3-L7 HydrophobicContact CG-CG 4.35Å; E3-L7 WeakPolarHBondContact O-CB 3.42Å; E3-L7 WeakPolarHBondContact O-CG 3.21Å; E3-L7 PolarHBondContact O-N 3.21Å; I5-L7 VanDerWaalsContact C-N 3.31Å; I5-L7 PolarHBondContact O-N 3.45Å; L7-L62 HydrophobicContact CD2-CD1 4.45Å; L7-K65 HydrophobicContact CD1-CB 4.31Å; L7-K65 HydrophobicContact CD1-CD 4.03Å; L7-K65 HydrophobicContact CD2-CB 3.96Å; L7-V66 HydrophobicContact CD2-CG2 4.02Å
8G79.2Confident82.4Confident61 Ų6164.9 Ų64.963%0.62936%0.363SS*.Hα-helixtrans-97.1-31.8-17300000115S4 I5S4-G8 WeakPolarHBondContact O-CA 3.16Å; S4-G8 PolarHBondContact O-N 2.96Å; I5-G8 PolarHBondContact O-N 3.4Å
9D71.6Confident82.8Confident63 Ų6367.5 Ų67.534%0.33737%0.367SS..  trans-14082.9179-177.72.8000110.5I5 Q11 A14I5-D9 PolarHBondContact O-N 3.29Å; D9-Q11 PolarHBondContact O-N 3.03Å; D9-Q11 PolarHBondContact OD1-N 3.31Å; D9-A14 WeakPolarHBondContact O-CB 3.19Å
10P65.9Low83.3Confident41 Ų4167.2 Ų67.227%0.26636%0.364SS..THydrogen-bonded Turntrans-64.5-19.7-175.722.2-30.7000113.7F98P10-F98 HydrophobicContact CB-CD1 3.4Å; P10-F98 HydrophobicContact CB-CD2 4.03Å; P10-F98 HydrophobicContact CB-CE1 3.29Å; P10-F98 HydrophobicContact CB-CE2 3.92Å; P10-F98 HydrophobicContact CB-CG 3.77Å; P10-F98 HydrophobicContact CB-CZ 3.55Å; P10-F98 WeakPolarHBondContact O-CD2 3.44Å; P10-F98 WeakPolarHBondContact O-CE2 3.39Å
11Q66.1Low83.8Confident157 Ų15764.3 Ų64.373%0.73435%0.348SS*.THydrogen-bonded Turntrans-97.4-26.4-165.7-69.3-176-0.600115D9D9-Q11 PolarHBondContact O-N 3.03Å; D9-Q11 PolarHBondContact OD1-N 3.31Å
12C67.6Low84.2Confident96 Ų9656 Ų5665%0.64931%0.307SS*.THydrogen-bonded Turntrans-114.9-42.6-174.2-67.60000114.9
13L82.8Confident84.5Confident96 Ų9655.6 Ų55.650%0.50331%0.308SS..THydrogen-bonded Turntrans-119.3-13.4-166.9-64.9175.9000114.3I5 I15 D16 A17I5-L13 HydrophobicContact CG2-CB 3.76Å; L13-I15 PolarHBondContact O-N 3.3Å; L13-D16 PolarHBondContact O-N 3.07Å; L13-A17 VanDerWaalsContact O-CB 3.22Å; L13-A17 WeakPolarHBondContact O-CB 3.46Å; L13-A17 PolarHBondContact O-N 3.06Å
14A86Confident84.8Confident0 Ų057.9 Ų57.90%032%0.318CS..Hα-helixtrans-60.6-45-172.400000113D9 A17 E18 F98 M102D9-A14 WeakPolarHBondContact O-CB 3.19Å; A14-A17 PolarHBondContact O-N 3.09Å; A14-E18 WeakPolarHBondContact O-CB 3.37Å; A14-E18 PolarHBondContact O-N 3.2Å; A14-F98 HydrophobicContact CB-CE2 3.49Å; A14-F98 VanDerWaalsContact CB-CE2 3.49Å; A14-F98 HydrophobicContact CB-CZ 3.84Å; A14-M102 VanDerWaalsContact C-CE 3.49Å; A14-M102 HydrophobicContact CB-CE 3.78Å
15I84.2Confident85Confident65 Ų6556.6 Ų56.633%0.33331%0.309SS..Hα-helixtrans-64.9-44.9-179.5-64.5172.3000110.9L13 A17 E18 R19 E101 M102L13-I15 PolarHBondContact O-N 3.3Å; I15-A17 VanDerWaalsContact C-N 3.34Å; I15-E18 PolarHBondContact O-N 3.02Å; I15-R19 WeakPolarHBondContact O-CB 3.42Å; I15-R19 PolarHBondContact O-N 2.85Å; I15-E101 HydrophobicContact CD1-CG 3.86Å; I15-M102 HydrophobicContact CG1-CE 3.94Å
16D87.8Confident85.2Confident65 Ų6555.1 Ų55.135%0.34830%0.3SS..Hα-helixtrans-66.2-38.4177.4-75.5-30.4000111.7L13 R19 L20L13-D16 PolarHBondContact O-N 3.07Å; D16-R19 PolarHBondContact O-N 3.4Å; D16-R19 IonicContact OD1-CZ 2.78Å; D16-R19 IonicContact OD1-NH1 3.77Å; D16-R19 PolarHBondContact OD1-NH1 2.92Å; D16-R19 IonicContact OD1-NH2 3.03Å; D16-R19 PolarHBondContact OD1-NH2 3.26Å; D16-L20 WeakPolarHBondContact O-CB 3.33Å; D16-L20 VanDerWaalsContact O-CG 3.23Å; D16-L20 WeakPolarHBondContact O-CG 3.41Å; D16-L20 PolarHBondContact O-N 3.1Å
17A91.6Very high85.5Confident7 Ų757.9 Ų57.96%0.05831%0.313CS..Hα-helixtrans-63.4-42.8175.500000112.1Y2 I5 I6 L13 A14 I15 M21Y2-A17 HydrophobicContact CD1-CB 4.14Å; Y2-A17 WeakPolarHBondContact CD1-O 3.37Å; I5-A17 HydrophobicContact CB-CB 4.08Å; I5-A17 HydrophobicContact CG2-CB 3.76Å; I6-A17 HydrophobicContact CG1-CB 4.13Å; L13-A17 VanDerWaalsContact O-CB 3.22Å; L13-A17 WeakPolarHBondContact O-CB 3.46Å; L13-A17 PolarHBondContact O-N 3.06Å; A14-A17 PolarHBondContact O-N 3.09Å; I15-A17 VanDerWaalsContact C-N 3.34Å; A17-M21 VanDerWaalsContact O-CB 3.23Å; A17-M21 WeakPolarHBondContact O-CB 3.48Å; A17-M21 PolarHBondContact O-N 2.86Å
18E92.2Very high85.9Confident1 Ų160.5 Ų60.51%0.00532%0.324CS..Hα-helixtrans-64.5-48175.5-165.9-70.3139.200110.9I6 A14 I15 L20 M21 W22 Y59 M102 M106 H109I6-E18 HydrophobicContact CD1-CB 3.85Å; I6-E18 HydrophobicContact CD1-CG 4.21Å; I6-E18 HydrophobicContact CG1-CB 4.35Å; A14-E18 WeakPolarHBondContact O-CB 3.37Å; A14-E18 PolarHBondContact O-N 3.2Å; I15-E18 PolarHBondContact O-N 3.02Å; E18-L20 PolarHBondContact O-N 3.03Å; E18-M21 HydrophobicContact CG-CE 4.11Å; E18-M21 WeakPolarHBondContact O-CB 3.44Å; E18-M21 PolarHBondContact O-N 2.63Å; E18-W22 PolarHBondContact O-N 3.31Å; E18-Y59 VanDerWaalsContact OE1-CE1 3.25Å; E18-Y59 WeakPolarHBondContact OE1-CE1 3.23Å; E18-Y59 PolarHBondContact OE1-OH 3.33Å; E18-M102 HydrophobicContact CB-CE 4.25Å; E18-M102 HydrophobicContact CB-SD 3.67Å; E18-M102 HydrophobicContact CG-SD 3.65Å; E18-M106 HydrophobicContact CG-CE 3.96Å; E18-H109 IonicContact OE1-CD2 2.94Å; E18-H109 PolarHBondContact OE1-CD2 2.76Å; E18-H109 IonicContact OE1-NE2 3.68Å; E18-H109 IonicContact OE2-CD2 2.61Å; E18-H109 IonicContact OE2-NE2 3.98Å; E18-H109 PolarHBondContact OE2-NE2 3.14Å
19R90.9Very high86.5Confident115 Ų11562 Ų6243%0.43431%0.313SS..Hα-helixtrans-58.3-46.3178-174.9-178.270.5-136.8-8.4112.1I15 D16 W22 Q23I15-R19 WeakPolarHBondContact O-CB 3.42Å; I15-R19 PolarHBondContact O-N 2.85Å; D16-R19 PolarHBondContact O-N 3.4Å; D16-R19 IonicContact OD1-CZ 2.78Å; D16-R19 IonicContact OD1-NH1 3.77Å; D16-R19 PolarHBondContact OD1-NH1 2.92Å; D16-R19 IonicContact OD1-NH2 3.03Å; D16-R19 PolarHBondContact OD1-NH2 3.26Å; R19-W22 PolarHBondContact O-N 3.31Å; R19-Q23 WeakPolarHBondContact O-CB 3.46Å; R19-Q23 VanDerWaalsContact O-CG 3.26Å; R19-Q23 WeakPolarHBondContact O-CG 3.34Å; R19-Q23 PolarHBondContact O-N 3.39Å
20L92.8Very high87.5Confident61 Ų6159.1 Ų59.132%0.31930%0.298SS..Hα-helixtrans-65.8-39.4178.7-73.5172.6000111.7Y2 D16 E18 Q23 H24Y2-L20 HydrophobicContact CE1-CB 4.15Å; D16-L20 WeakPolarHBondContact O-CB 3.33Å; D16-L20 VanDerWaalsContact O-CG 3.23Å; D16-L20 WeakPolarHBondContact O-CG 3.41Å; D16-L20 PolarHBondContact O-N 3.1Å; E18-L20 PolarHBondContact O-N 3.03Å; L20-Q23 PolarHBondContact O-N 3.01Å; L20-H24 WeakPolarHBondContact O-CB 3.4Å; L20-H24 PolarHBondContact O-CD2 3.15Å; L20-H24 PolarHBondContact O-N 3.29Å
21M93.3Very high88.7Confident6 Ų658.9 Ų58.93%0.0329%0.294CS..Hα-helixtrans-61.8-47.9174.3177.7-170.271.900111.2Y2 I6 A17 E18 Q23 C25 F26 Y58 Y59 L62Y2-M21 HydrophobicContact CD1-CB 4.34Å; Y2-M21 HydrophobicContact CD2-CB 3.66Å; Y2-M21 HydrophobicContact CD2-CG 3.89Å; Y2-M21 HydrophobicContact CE2-CB 4.19Å; Y2-M21 HydrophobicContact CG-CB 3.75Å; Y2-M21 HydrophobicContact CG-CG 4.25Å; I6-M21 HydrophobicContact CD1-CE 4.38Å; A17-M21 VanDerWaalsContact O-CB 3.23Å; A17-M21 WeakPolarHBondContact O-CB 3.48Å; A17-M21 PolarHBondContact O-N 2.86Å; E18-M21 HydrophobicContact CG-CE 4.11Å; E18-M21 WeakPolarHBondContact O-CB 3.44Å; E18-M21 PolarHBondContact O-N 2.63Å; M21-Q23 VanDerWaalsContact C-N 3.35Å; M21-Q23 PolarHBondContact O-N 3.48Å; M21-C25 WeakPolarHBondContact O-CB 3.47Å; M21-C25 PolarHBondContact O-N 3.33Å; M21-F26 HydrophobicContact CG-CE2 4.4Å; M21-Y58 HydrophobicContact CE-CE1 3.57Å; M21-Y58 HydrophobicContact SD-CE1 3.41Å; M21-Y58 WeakPolarHBondContact SD-CE1 3.27Å; M21-Y58 VanDerWaalsContact SD-CZ 3.59Å; M21-Y58 PolarHBondContact SD-OH 3.2Å; M21-Y59 HydrophobicContact CE-CE1 4.03Å; M21-L62 HydrophobicContact CE-CD2 4.22Å
22W94.8Very high90Very high9 Ų954.6 Ų54.63%0.03428%0.28CS..Iπ-helixtrans-55.1-52.3174.7172.1-113.3000111.3E18 R19 F26 Q27 Y59 H109 D112 I113 Y116E18-W22 PolarHBondContact O-N 3.31Å; R19-W22 PolarHBondContact O-N 3.31Å; W22-F26 HydrophobicContact CD2-CB 4.49Å; W22-F26 HydrophobicContact CE3-CB 3.73Å; W22-F26 AromaticContact CE3-CD2 3.91Å; W22-F26 HydrophobicContact CE3-CD2 3.91Å; W22-F26 HydrophobicContact CE3-CG 4.19Å; W22-F26 HydrophobicContact CZ3-CB 3.75Å; W22-F26 HydrophobicContact CZ3-CD2 4.4Å; W22-F26 HydrophobicContact CZ3-CG 4.32Å; W22-F26 PolarHBondContact O-N 3.2Å; W22-F26 VanDerWaalsContact O-N 3.14Å; W22-Q27 HydrophobicContact CZ2-CB 4.41Å; W22-Q27 PolarHBondContact O-N 3.27Å; W22-Y59 WeakPolarHBondContact CB-OH 3.29Å; W22-Y59 AromaticContact CE3-CE2 3.98Å; W22-Y59 HydrophobicContact CE3-CE2 3.98Å; W22-Y59 HydrophobicContact CZ3-CE2 4.27Å; W22-H109 AromaticContact CD1-CE1 3.27Å; W22-H109 AromaticContact CD1-ND1 3.57Å; W22-H109 AromaticContact CD1-NE2 3.89Å; W22-H109 HydrophobicContact CD2-CB 4.02Å; W22-H109 AromaticContact CD2-CE1 3.74Å; W22-H109 AromaticContact CD2-CG 3.52Å; W22-H109 AromaticContact CD2-ND1 3.28Å; W22-H109 VanDerWaalsContact CD2-ND1 3.28Å; W22-H109 AromaticContact CE2-CE1 3.78Å; W22-H109 AromaticContact CE2-CG 3.91Å; W22-H109 AromaticContact CE2-ND1 3.22Å; W22-H109 HydrophobicContact CE3-CB 3.65Å; W22-H109 AromaticContact CE3-CG 3.68Å; W22-H109 AromaticContact CE3-ND1 3.87Å; W22-H109 AromaticContact CG-CD2 3.95Å; W22-H109 AromaticContact CG-CE1 3.41Å; W22-H109 VanDerWaalsContact CG-CE1 3.41Å; W22-H109 AromaticContact CG-CG 3.83Å; W22-H109 AromaticContact CG-ND1 3.5Å; W22-H109 AromaticContact CG-NE2 3.7Å; W22-H109 HydrophobicContact CH2-CB 4.13Å; W22-H109 HydrophobicContact CZ2-CB 4.47Å; W22-H109 AromaticContact CZ2-ND1 3.75Å; W22-H109 HydrophobicContact CZ3-CB 3.72Å; W22-H109 AromaticContact NE1-CE1 3.49Å; W22-H109 PolarHBondContact NE1-CE1 3.21Å; W22-H109 AromaticContact NE1-ND1 3.4Å; W22-H109 PolarHBondContact NE1-ND1 3.12Å; W22-D112 HydrophobicContact CH2-CB 3.68Å; W22-D112 HydrophobicContact CZ2-CB 3.72Å; W22-I113 HydrophobicContact CH2-CG1 4.12Å; W22-I113 HydrophobicContact CZ3-CD1 4.11Å; W22-I113 HydrophobicContact CZ3-CG1 3.86Å; W22-Y116 AromaticContact CH2-CE2 3.86Å; W22-Y116 HydrophobicContact CH2-CE2 3.86Å; W22-Y116 HydrophobicContact CZ2-CE2 4.13Å
23Q94.3Very high91.2Very high64 Ų6451.3 Ų51.330%0.29926%0.255SS..Iπ-helixtrans-61.2-52.9-176.4-75.1176.9-13.300112.3R19 L20 M21 Q28R19-Q23 WeakPolarHBondContact O-CB 3.46Å; R19-Q23 VanDerWaalsContact O-CG 3.26Å; R19-Q23 WeakPolarHBondContact O-CG 3.34Å; R19-Q23 PolarHBondContact O-N 3.39Å; L20-Q23 PolarHBondContact O-N 3.01Å; M21-Q23 VanDerWaalsContact C-N 3.35Å; M21-Q23 PolarHBondContact O-N 3.48Å; Q23-Q28 WeakPolarHBondContact O-CB 3.05Å; Q23-Q28 WeakPolarHBondContact O-CG 3.49Å; Q23-Q28 PolarHBondContact O-N 3.21Å
24H92.5Very high91.4Very high97 Ų9747.7 Ų47.745%0.44924%0.238SC..Iπ-helixtrans-83.1-34.2-171.5-67.4-54.2000114L20 Q28L20-H24 WeakPolarHBondContact O-CB 3.4Å; L20-H24 PolarHBondContact O-CD2 3.15Å; L20-H24 PolarHBondContact O-N 3.29Å; H24-Q28 PolarHBondContact ND1-OE1 3.28Å
25C91Very high91.6Very high64 Ų6456.8 Ų56.843%0.43227%0.273SS..Iπ-helixtrans-90.3-25.6-176.1-57.80000113M21M21-C25 WeakPolarHBondContact O-CB 3.47Å; M21-C25 PolarHBondContact O-N 3.33Å
26F92.8Very high91.9Very high26 Ų2656.6 Ų56.611%0.11427%0.272CS..Iπ-helixtrans-127.2-59.9-172.2-54.1-63000112.8M21 W22 F29 F30 A55 Y58 Y59M21-F26 HydrophobicContact CG-CE2 4.4Å; W22-F26 HydrophobicContact CD2-CB 4.49Å; W22-F26 HydrophobicContact CE3-CB 3.73Å; W22-F26 AromaticContact CE3-CD2 3.91Å; W22-F26 HydrophobicContact CE3-CD2 3.91Å; W22-F26 HydrophobicContact CE3-CG 4.19Å; W22-F26 HydrophobicContact CZ3-CB 3.75Å; W22-F26 HydrophobicContact CZ3-CD2 4.4Å; W22-F26 HydrophobicContact CZ3-CG 4.32Å; W22-F26 PolarHBondContact O-N 3.2Å; W22-F26 VanDerWaalsContact O-N 3.14Å; F26-F29 PolarHBondContact O-N 3.41Å; F26-F30 HydrophobicContact CB-CD2 4.25Å; F26-F30 HydrophobicContact CB-CE2 4.48Å; F26-F30 HydrophobicContact CD1-CE2 4.14Å; F26-F30 WeakPolarHBondContact O-CD2 3.36Å; F26-F30 PolarHBondContact O-N 2.93Å; F26-A55 HydrophobicContact CD1-CB 3.62Å; F26-A55 HydrophobicContact CE1-CB 3.35Å; F26-A55 HydrophobicContact CG-CB 4.49Å; F26-A55 HydrophobicContact CZ-CB 4.04Å; F26-Y58 HydrophobicContact CE2-CD1 4.43Å; F26-Y58 HydrophobicContact CZ-CD1 4.29Å; F26-Y59 AromaticContact CD2-CE2 3.82Å; F26-Y59 HydrophobicContact CD2-CE2 3.82Å; F26-Y59 HydrophobicContact CE2-CD2 4.45Å; F26-Y59 AromaticContact CE2-CE2 3.64Å; F26-Y59 HydrophobicContact CE2-CE2 3.64Å; F26-Y59 HydrophobicContact CZ-CE2 4.43Å
27Q92.6Very high91.9Very high60 Ų6054.1 Ų54.128%0.2826%0.261SS..Iπ-helixtrans-62.2-53.5-170.1-172.3-178.7-6.200112.7W22 F29 F30 D31W22-Q27 HydrophobicContact CZ2-CB 4.41Å; W22-Q27 PolarHBondContact O-N 3.27Å; Q27-F29 PolarHBondContact O-N 3.3Å; Q27-F30 PolarHBondContact O-N 3.02Å; Q27-D31 WeakPolarHBondContact CG-OD2 3.17Å; Q27-D31 PolarHBondContact NE2-OD2 3.09Å; Q27-D31 WeakPolarHBondContact O-CB 3.38Å; Q27-D31 PolarHBondContact O-N 3.19Å
28Q93Very high91.6Very high117 Ų11760.3 Ų60.355%0.54730%0.298SS..Hα-helixtrans-59.5-23.5180-74.6175.3-1.700112.8Q23 H24 P32Q23-Q28 WeakPolarHBondContact O-CB 3.05Å; Q23-Q28 WeakPolarHBondContact O-CG 3.49Å; Q23-Q28 PolarHBondContact O-N 3.21Å; H24-Q28 PolarHBondContact ND1-OE1 3.28Å; Q28-P32 WeakPolarHBondContact O-CD 3.06Å
29F92.3Very high91.5Very high92 Ų9270 Ų7040%0.40433%0.334SS..Hα-helixtrans-86.4-46.5177.8-173.1-101.4000112.5F26 Q27 I33 L51F26-F29 PolarHBondContact O-N 3.41Å; Q27-F29 PolarHBondContact O-N 3.3Å; F29-I33 HydrophobicContact CD1-CD1 3.76Å; F29-I33 HydrophobicContact CD2-CD1 4.49Å; F29-I33 HydrophobicContact CE1-CD1 3.4Å; F29-I33 HydrophobicContact CE2-CD1 4.2Å; F29-I33 HydrophobicContact CG-CD1 4.29Å; F29-I33 HydrophobicContact CZ-CD1 3.64Å; F29-I33 VanDerWaalsContact O-CD1 3.26Å; F29-I33 WeakPolarHBondContact O-CD1 3.31Å; F29-I33 VanDerWaalsContact O-CG1 3.28Å; F29-I33 WeakPolarHBondContact O-CG1 3.36Å; F29-L51 HydrophobicContact CD1-CD1 4.49Å; F29-L51 HydrophobicContact CE1-CD1 3.54Å; F29-L51 HydrophobicContact CZ-CD1 3.76Å
30F93.7Very high91.5Very high3 Ų367 Ų671%0.01333%0.327CS..Hα-helixtrans-88.7-25-172.3-68.6-61.6000115.1F26 Q27 I33 S34 A48 L51 L52 Y116F26-F30 HydrophobicContact CB-CD2 4.25Å; F26-F30 HydrophobicContact CB-CE2 4.48Å; F26-F30 HydrophobicContact CD1-CE2 4.14Å; F26-F30 WeakPolarHBondContact O-CD2 3.36Å; F26-F30 PolarHBondContact O-N 2.93Å; Q27-F30 PolarHBondContact O-N 3.02Å; F30-I33 HydrophobicContact CD1-CD1 4.37Å; F30-I33 PolarHBondContact O-N 3.01Å; F30-S34 WeakPolarHBondContact O-CB 3.42Å; F30-S34 PolarHBondContact O-N 3.45Å; F30-S34 PolarHBondContact O-OG 3.26Å; F30-A48 HydrophobicContact CE1-CB 4.23Å; F30-A48 WeakPolarHBondContact CE1-O 3.35Å; F30-L51 HydrophobicContact CE1-CB 4.32Å; F30-L51 HydrophobicContact CZ-CB 3.67Å; F30-L52 HydrophobicContact CD1-CD1 4.17Å; F30-L52 HydrophobicContact CD1-CD2 3.88Å; F30-L52 HydrophobicContact CD1-CG 3.95Å; F30-L52 HydrophobicContact CD2-CD2 3.72Å; F30-L52 HydrophobicContact CD2-CG 4.49Å; F30-L52 HydrophobicContact CE1-CD1 4.02Å; F30-L52 HydrophobicContact CE1-CD2 3.79Å; F30-L52 HydrophobicContact CE1-CG 3.49Å; F30-L52 VanDerWaalsContact CE1-CG 3.49Å; F30-L52 HydrophobicContact CE2-CD2 3.62Å; F30-L52 HydrophobicContact CE2-CG 4.08Å; F30-L52 HydrophobicContact CG-CD2 3.86Å; F30-L52 HydrophobicContact CG-CG 4.44Å; F30-L52 HydrophobicContact CZ-CB 4.47Å; F30-L52 HydrophobicContact CZ-CD2 3.65Å; F30-L52 HydrophobicContact CZ-CG 3.56Å; F30-Y116 HydrophobicContact CB-CD1 4.08Å; F30-Y116 HydrophobicContact CB-CD2 3.63Å; F30-Y116 HydrophobicContact CB-CE1 4.27Å; F30-Y116 HydrophobicContact CB-CE2 3.84Å; F30-Y116 HydrophobicContact CB-CG 3.78Å; F30-Y116 HydrophobicContact CD2-CD2 4.45Å; F30-Y116 HydrophobicContact CG-CD2 4.25Å
31D91.4Very high91.4Very high36 Ų3671.6 Ų71.619%0.19334%0.344CS..Hα-helixtrans-57.8-50.7175.2-93-26.5000111.6Q27 I33 S34 R35 Y116Q27-D31 WeakPolarHBondContact CG-OD2 3.17Å; Q27-D31 PolarHBondContact NE2-OD2 3.09Å; Q27-D31 WeakPolarHBondContact O-CB 3.38Å; Q27-D31 PolarHBondContact O-N 3.19Å; D31-I33 PolarHBondContact O-N 3.03Å; D31-S34 PolarHBondContact O-OG 3.1Å; D31-R35 WeakPolarHBondContact O-CG 3.13Å; D31-R35 PolarHBondContact O-N 3.01Å; D31-Y116 WeakPolarHBondContact OD1-CE1 3.26Å; D31-Y116 PolarHBondContact OD1-OH 3.07Å
32P92.4Very high91.1Very high67 Ų6774.2 Ų74.244%0.43537%0.367SS..Hα-helixtrans-66.1-36.6177.3-2234.3000113.5Q28 N36Q28-P32 WeakPolarHBondContact O-CD 3.06Å; P32-N36 WeakPolarHBondContact O-CB 3.27Å; P32-N36 PolarHBondContact O-N 3.46Å; P32-N36 PolarHBondContact O-ND2 3.34Å
33I92.3Very high91Very high26 Ų2679.3 Ų79.313%0.13339%0.391CS..Hα-helixtrans-66.7-47.8-179.3-68.4173.3000110.4F29 F30 D31 R35 N36 A37 L40 A48 I120F29-I33 HydrophobicContact CD1-CD1 3.76Å; F29-I33 HydrophobicContact CD2-CD1 4.49Å; F29-I33 HydrophobicContact CE1-CD1 3.4Å; F29-I33 HydrophobicContact CE2-CD1 4.2Å; F29-I33 HydrophobicContact CG-CD1 4.29Å; F29-I33 HydrophobicContact CZ-CD1 3.64Å; F29-I33 VanDerWaalsContact O-CD1 3.26Å; F29-I33 WeakPolarHBondContact O-CD1 3.31Å; F29-I33 VanDerWaalsContact O-CG1 3.28Å; F29-I33 WeakPolarHBondContact O-CG1 3.36Å; F30-I33 HydrophobicContact CD1-CD1 4.37Å; F30-I33 PolarHBondContact O-N 3.01Å; D31-I33 PolarHBondContact O-N 3.03Å; I33-R35 VanDerWaalsContact C-N 3.35Å; I33-R35 PolarHBondContact O-N 3.05Å; I33-N36 CarbonylContact O-C 3.45Å; I33-N36 PolarHBondContact O-N 2.84Å; I33-A37 WeakPolarHBondContact O-CA 3.49Å; I33-A37 PolarHBondContact O-N 2.88Å; I33-L40 HydrophobicContact CB-CD1 4.3Å; I33-L40 HydrophobicContact CG1-CD1 4.39Å; I33-L40 HydrophobicContact CG2-CD1 3.79Å; I33-A48 HydrophobicContact CD1-CB 4.35Å; I33-A48 HydrophobicContact CG2-CB 4.07Å; I33-I120 HydrophobicContact CG2-CD1 3.71Å; I33-I120 HydrophobicContact CG2-CG1 4.07Å
34S88.3Confident90.8Very high21 Ų2181 Ų8115%0.14740%0.399CS..Hα-helixtrans-62.8-39.7-17961.10000112.4F30 D31 N36F30-S34 WeakPolarHBondContact O-CB 3.42Å; F30-S34 PolarHBondContact O-N 3.45Å; F30-S34 PolarHBondContact O-OG 3.26Å; D31-S34 PolarHBondContact O-OG 3.1Å; S34-N36 VanDerWaalsContact C-N 3.31Å; S34-N36 PolarHBondContact O-N 2.74Å
35R89.1Confident90.7Very high190 Ų19077.4 Ų77.472%0.71738%0.383SS*.Hα-helixtrans-68.4-27.2176.6-67.2177.4-164.6172.76.7113.7D31 I33D31-R35 WeakPolarHBondContact O-CG 3.13Å; D31-R35 PolarHBondContact O-N 3.01Å; I33-R35 VanDerWaalsContact C-N 3.35Å; I33-R35 PolarHBondContact O-N 3.05Å
36N91.1Very high90.7Very high62 Ų6279.9 Ų79.933%0.33238%0.383SS..THydrogen-bonded Turntrans-11316-176.4-66.1-69.6000113.4P32 I33 S34 T38 R39 L40P32-N36 WeakPolarHBondContact O-CB 3.27Å; P32-N36 PolarHBondContact O-N 3.46Å; P32-N36 PolarHBondContact O-ND2 3.34Å; I33-N36 CarbonylContact O-C 3.45Å; I33-N36 PolarHBondContact O-N 2.84Å; S34-N36 VanDerWaalsContact C-N 3.31Å; S34-N36 PolarHBondContact O-N 2.74Å; N36-T38 PolarHBondContact O-N 3.28Å; N36-T38 VanDerWaalsContact O-N 3.08Å; N36-R39 PolarHBondContact O-N 2.96Å; N36-L40 PolarHBondContact O-N 3.13Å
37A87.1Confident90.6Very high12 Ų1285.2 Ų85.210%0.09941%0.406CS..G310 helixtrans-53.8-37-172.500000112.9I33 R39 L40 L45I33-A37 WeakPolarHBondContact O-CA 3.49Å; I33-A37 PolarHBondContact O-N 2.88Å; A37-R39 PolarHBondContact O-N 2.64Å; A37-L40 PolarHBondContact O-N 3.12Å; A37-L45 HydrophobicContact CB-CD2 4.14Å
38T86.1Confident90.6Very high137 Ų13782.4 Ų82.484%0.8439%0.394SS*.G310 helixtrans-66-17.9177.855.80000114.6N36N36-T38 PolarHBondContact O-N 3.28Å; N36-T38 VanDerWaalsContact O-N 3.08Å
39R90.3Very high90.4Very high204 Ų20478.9 Ų78.977%0.7738%0.378SS*.G310 helixtrans-101.6-10.7-178.5-61179.5177.6177.7-2.3113.4N36 A37N36-R39 PolarHBondContact O-N 2.96Å; A37-R39 PolarHBondContact O-N 2.64Å
40L89.7Confident90.3Very high52 Ų5279.8 Ų79.827%0.27238%0.383SS..SBendtrans-88.2152-175.8-67.1173.7000111.5I33 N36 A37 Q44 L45I33-L40 HydrophobicContact CB-CD1 4.3Å; I33-L40 HydrophobicContact CG1-CD1 4.39Å; I33-L40 HydrophobicContact CG2-CD1 3.79Å; N36-L40 PolarHBondContact O-N 3.13Å; A37-L40 PolarHBondContact O-N 3.12Å; L40-Q44 HydrophobicContact CB-CB 4.42Å; L40-L45 HydrophobicContact CB-CD2 3.91Å; L40-L45 HydrophobicContact CB-CG 4.1Å; L40-L45 HydrophobicContact CD1-CD2 4.06Å
41K90.8Very high90.3Very high158 Ų15882.8 Ų82.869%0.68740%0.399SS*.  trans-70.8148.7175.5-63.7-178.8-179.6179.90110E43 Q44 L45K41-E43 PolarHBondContact O-N 3.29Å; K41-E43 VanDerWaalsContact O-N 3.08Å; K41-Q44 HydrophobicContact CB-CG 4.39Å; K41-Q44 WeakPolarHBondContact O-CB 3.38Å; K41-Q44 PolarHBondContact O-N 2.76Å; K41-L45 PolarHBondContact O-N 2.94Å; K41-L45 VanDerWaalsContact O-N 3.15Å
42A87.9Confident90.3Very high62 Ų6281.1 Ų81.151%0.51239%0.39SS..Hα-helixtrans-51.9-35.7178.200000113.4L45 R46A42-L45 PolarHBondContact O-N 3.46Å; A42-R46 PolarHBondContact O-N 3.13Å
43E91.5Very high90.2Very high115 Ų11582.5 Ų82.554%0.53739%0.39SS..Hα-helixtrans-62.1-43175.6-168.159.1-14200112.8K41 L45 R46 K47K41-E43 PolarHBondContact O-N 3.29Å; K41-E43 VanDerWaalsContact O-N 3.08Å; E43-L45 VanDerWaalsContact C-N 3.34Å; E43-R46 PolarHBondContact O-N 2.91Å; E43-R46 IonicContact OE1-NH1 2.72Å; E43-R46 PolarHBondContact OE1-NH1 3.46Å; E43-R46 IonicContact OE2-CZ 3.66Å; E43-R46 IonicContact OE2-NH1 3.5Å; E43-R46 PolarHBondContact OE2-NH1 3.13Å; E43-R46 IonicContact OE2-NH2 3.2Å; E43-K47 PolarHBondContact O-N 2.92Å
44Q91.6Very high90.2Very high101 Ų10185.4 Ų85.447%0.47241%0.409SS..Hα-helixtrans-67-39.6179-63.6173.7-58.800110.6L40 K41 K47 A48L40-Q44 HydrophobicContact CB-CB 4.42Å; K41-Q44 HydrophobicContact CB-CG 4.39Å; K41-Q44 WeakPolarHBondContact O-CB 3.38Å; K41-Q44 PolarHBondContact O-N 2.76Å; Q44-K47 PolarHBondContact O-N 2.64Å; Q44-A48 WeakPolarHBondContact O-CB 3.37Å; Q44-A48 PolarHBondContact O-N 3.07Å
45L90.1Very high90.5Very high21 Ų2184.4 Ų84.411%0.1140%0.402CS..Hα-helixtrans-66.5-39.4176.6-61.1172.2000111.7A37 L40 K41 A42 E43 A48 M49 I120 Y121A37-L45 HydrophobicContact CB-CD2 4.14Å; L40-L45 HydrophobicContact CB-CD2 3.91Å; L40-L45 HydrophobicContact CB-CG 4.1Å; L40-L45 HydrophobicContact CD1-CD2 4.06Å; K41-L45 PolarHBondContact O-N 2.94Å; K41-L45 VanDerWaalsContact O-N 3.15Å; A42-L45 PolarHBondContact O-N 3.46Å; E43-L45 VanDerWaalsContact C-N 3.34Å; L45-A48 PolarHBondContact O-N 3.44Å; L45-M49 WeakPolarHBondContact O-CG 3.34Å; L45-M49 PolarHBondContact O-N 2.88Å; L45-I120 HydrophobicContact CB-CG2 4.15Å; L45-I120 HydrophobicContact CD2-CG2 3.78Å; L45-Y121 HydrophobicContact CB-CE2 4.11Å
46R89.8Confident90.6Very high116 Ų11676.7 Ų76.744%0.43838%0.377SS..Hα-helixtrans-61.5-48.7175-166.1-173.2-53121.57.3111.5A42 E43 A48 M49 E50A42-R46 PolarHBondContact O-N 3.13Å; E43-R46 PolarHBondContact O-N 2.91Å; E43-R46 IonicContact OE1-NH1 2.72Å; E43-R46 PolarHBondContact OE1-NH1 3.46Å; E43-R46 IonicContact OE2-CZ 3.66Å; E43-R46 IonicContact OE2-NH1 3.5Å; E43-R46 PolarHBondContact OE2-NH1 3.13Å; E43-R46 IonicContact OE2-NH2 3.2Å; R46-A48 VanDerWaalsContact C-N 3.3Å; R46-A48 PolarHBondContact O-N 2.52Å; R46-M49 WeakPolarHBondContact O-CB 3.32Å; R46-M49 PolarHBondContact O-N 3.17Å; R46-M49 VanDerWaalsContact O-N 3.1Å; R46-E50 PolarHBondContact O-N 3.25Å
47K91.6Very high90.7Very high137 Ų13777.2 Ų77.260%0.59638%0.379SS*.Hα-helixtrans-61.3-38.9176.7-169.6170.7-175.2174.10112.2E43 Q44 M49 E50 L51E43-K47 PolarHBondContact O-N 2.92Å; Q44-K47 PolarHBondContact O-N 2.64Å; K47-M49 VanDerWaalsContact C-N 3.34Å; K47-M49 PolarHBondContact O-N 3.16Å; K47-E50 PolarHBondContact O-N 3.02Å; K47-L51 WeakPolarHBondContact O-CG 3.05Å; K47-L51 PolarHBondContact O-N 3.28Å; K47-L51 VanDerWaalsContact O-N 3.1Å
48A91.8Very high91Very high2 Ų279.3 Ų79.32%0.01739%0.385CS..Hα-helixtrans-62.6-40.5174.100000112F30 I33 Q44 L45 R46 L51 L52 I120F30-A48 HydrophobicContact CE1-CB 4.23Å; F30-A48 WeakPolarHBondContact CE1-O 3.35Å; I33-A48 HydrophobicContact CD1-CB 4.35Å; I33-A48 HydrophobicContact CG2-CB 4.07Å; Q44-A48 WeakPolarHBondContact O-CB 3.37Å; Q44-A48 PolarHBondContact O-N 3.07Å; L45-A48 PolarHBondContact O-N 3.44Å; R46-A48 VanDerWaalsContact C-N 3.3Å; R46-A48 PolarHBondContact O-N 2.52Å; A48-L51 PolarHBondContact O-N 3.45Å; A48-L52 WeakPolarHBondContact O-CG 3.25Å; A48-L52 PolarHBondContact O-N 2.9Å; A48-I120 HydrophobicContact CB-CD1 3.99Å
49M89.4Confident91.4Very high42 Ų4272.8 Ų72.821%0.20735%0.345CS..Hα-helixtrans-65.7-39.7176.2-76.3-62.3-66.300113.3L45 R46 K47 L51 L52 H53 R117 I120 Y121L45-M49 WeakPolarHBondContact O-CG 3.34Å; L45-M49 PolarHBondContact O-N 2.88Å; R46-M49 WeakPolarHBondContact O-CB 3.32Å; R46-M49 PolarHBondContact O-N 3.17Å; R46-M49 VanDerWaalsContact O-N 3.1Å; K47-M49 VanDerWaalsContact C-N 3.34Å; K47-M49 PolarHBondContact O-N 3.16Å; M49-L51 VanDerWaalsContact C-N 3.33Å; M49-L52 PolarHBondContact O-N 3.1Å; M49-L52 HydrophobicContact SD-CD1 4.2Å; M49-H53 PolarHBondContact O-N 3.15Å; M49-R117 HydrophobicContact CE-CB 4.27Å; M49-R117 HydrophobicContact CE-CG 4.17Å; M49-R117 HydrophobicContact SD-CB 4.2Å; M49-R117 HydrophobicContact SD-CG 4.11Å; M49-I120 HydrophobicContact CG-CG2 4.09Å; M49-I120 HydrophobicContact SD-CB 4.46Å; M49-I120 HydrophobicContact SD-CG2 4.18Å; M49-Y121 HydrophobicContact CE-CD2 4.47Å; M49-Y121 HydrophobicContact CG-CD2 3.5Å; M49-Y121 VanDerWaalsContact CG-CD2 3.5Å; M49-Y121 HydrophobicContact CG-CE2 3.54Å; M49-Y121 HydrophobicContact SD-CD2 3.87Å
50E91.2Very high91.5Very high112 Ų11267.4 Ų67.452%0.52333%0.327SS..Hα-helixtrans-59.6-45.6173.5-71.4168.1-169.100110.8R46 K47 L52 H53 V54R46-E50 PolarHBondContact O-N 3.25Å; K47-E50 PolarHBondContact O-N 3.02Å; E50-L52 PolarHBondContact O-N 2.77Å; E50-H53 WeakPolarHBondContact O-CB 3.41Å; E50-H53 PolarHBondContact O-N 3.23Å; E50-V54 WeakPolarHBondContact O-CG2 3.48Å; E50-V54 PolarHBondContact O-N 3.49Å
51L92.7Very high91.7Very high66 Ų6667.9 Ų67.935%0.34633%0.334SS..Hα-helixtrans-65-37.4177.1-68.1170.8000112.4F29 F30 K47 A48 M49 H53 V54 A55F29-L51 HydrophobicContact CD1-CD1 4.49Å; F29-L51 HydrophobicContact CE1-CD1 3.54Å; F29-L51 HydrophobicContact CZ-CD1 3.76Å; F30-L51 HydrophobicContact CE1-CB 4.32Å; F30-L51 HydrophobicContact CZ-CB 3.67Å; K47-L51 WeakPolarHBondContact O-CG 3.05Å; K47-L51 PolarHBondContact O-N 3.28Å; K47-L51 VanDerWaalsContact O-N 3.1Å; A48-L51 PolarHBondContact O-N 3.45Å; M49-L51 VanDerWaalsContact C-N 3.33Å; L51-H53 VanDerWaalsContact C-N 3.32Å; L51-H53 PolarHBondContact O-N 3.43Å; L51-V54 PolarHBondContact O-N 3.2Å; L51-A55 WeakPolarHBondContact O-CB 3.34Å; L51-A55 PolarHBondContact O-N 3.14Å
52L91.8Very high91.9Very high0 Ų060.4 Ų60.40%030%0.302CS..Hα-helixtrans-66.2-34173.7-73.6165000112.4F30 A48 M49 E50 A55 T56 I113 Y116 R117 I120F30-L52 HydrophobicContact CD1-CD1 4.17Å; F30-L52 HydrophobicContact CD1-CD2 3.88Å; F30-L52 HydrophobicContact CD1-CG 3.95Å; F30-L52 HydrophobicContact CD2-CD2 3.72Å; F30-L52 HydrophobicContact CD2-CG 4.49Å; F30-L52 HydrophobicContact CE1-CD1 4.02Å; F30-L52 HydrophobicContact CE1-CD2 3.79Å; F30-L52 HydrophobicContact CE1-CG 3.49Å; F30-L52 VanDerWaalsContact CE1-CG 3.49Å; F30-L52 HydrophobicContact CE2-CD2 3.62Å; F30-L52 HydrophobicContact CE2-CG 4.08Å; F30-L52 HydrophobicContact CG-CD2 3.86Å; F30-L52 HydrophobicContact CG-CG 4.44Å; F30-L52 HydrophobicContact CZ-CB 4.47Å; F30-L52 HydrophobicContact CZ-CD2 3.65Å; F30-L52 HydrophobicContact CZ-CG 3.56Å; A48-L52 WeakPolarHBondContact O-CG 3.25Å; A48-L52 PolarHBondContact O-N 2.9Å; M49-L52 PolarHBondContact O-N 3.1Å; M49-L52 HydrophobicContact SD-CD1 4.2Å; E50-L52 PolarHBondContact O-N 2.77Å; L52-A55 PolarHBondContact O-N 3.17Å; L52-T56 PolarHBondContact O-N 3.36Å; L52-T56 PolarHBondContact O-OG1 2.77Å; L52-I113 HydrophobicContact CB-CG2 4.44Å; L52-I113 HydrophobicContact CD2-CG2 3.95Å; L52-Y116 HydrophobicContact CD2-CD2 4.24Å; L52-R117 HydrophobicContact CB-CG 3.74Å; L52-R117 HydrophobicContact CD1-CB 4.44Å; L52-R117 HydrophobicContact CD1-CG 3.65Å; L52-R117 HydrophobicContact CG-CG 4.16Å; L52-I120 HydrophobicContact CD1-CD1 3.6Å
53H90.2Very high92.2Very high96 Ų9657.7 Ų57.744%0.44428%0.279SS..Hα-helixtrans-65.7-44.2173-176.368.6000111.2M49 E50 L51 A55 T56 N57M49-H53 PolarHBondContact O-N 3.15Å; E50-H53 WeakPolarHBondContact O-CB 3.41Å; E50-H53 PolarHBondContact O-N 3.23Å; L51-H53 VanDerWaalsContact C-N 3.32Å; L51-H53 PolarHBondContact O-N 3.43Å; H53-A55 PolarHBondContact O-N 3.05Å; H53-T56 WeakPolarHBondContact O-CB 3.35Å; H53-T56 PolarHBondContact O-N 3.26Å; H53-N57 PolarHBondContact CD2-ND2 3.4Å; H53-N57 PolarHBondContact NE2-ND2 3.39Å; H53-N57 PolarHBondContact O-N 2.9Å; H53-N57 PolarHBondContact O-ND2 2.72Å
54V92.2Very high92.2Very high88 Ų8858.6 Ų58.653%0.53328%0.277SS..Hα-helixtrans-59.3-45.9173.5174.50000111E50 L51 T56 N57 Y58E50-V54 WeakPolarHBondContact O-CG2 3.48Å; E50-V54 PolarHBondContact O-N 3.49Å; L51-V54 PolarHBondContact O-N 3.2Å; V54-T56 VanDerWaalsContact C-N 3.34Å; V54-T56 PolarHBondContact O-N 3.01Å; V54-N57 PolarHBondContact O-N 3.09Å; V54-Y58 WeakPolarHBondContact O-CB 3.3Å; V54-Y58 PolarHBondContact O-N 2.95Å
55A93.5Very high92.3Very high0 Ų058.3 Ų58.30%028%0.275CS..Hα-helixtrans-59.5-43.3177.200000112.1F26 L51 L52 H53 Y58 Y59 I113F26-A55 HydrophobicContact CD1-CB 3.62Å; F26-A55 HydrophobicContact CE1-CB 3.35Å; F26-A55 HydrophobicContact CG-CB 4.49Å; F26-A55 HydrophobicContact CZ-CB 4.04Å; L51-A55 WeakPolarHBondContact O-CB 3.34Å; L51-A55 PolarHBondContact O-N 3.14Å; L52-A55 PolarHBondContact O-N 3.17Å; H53-A55 PolarHBondContact O-N 3.05Å; A55-Y58 PolarHBondContact O-N 3.24Å; A55-Y59 WeakPolarHBondContact O-CD2 3.39Å; A55-Y59 PolarHBondContact O-N 3.34Å; A55-I113 HydrophobicContact CB-CD1 3.74Å; A55-I113 HydrophobicContact CB-CG1 4.31Å
56T92.4Very high92.4Very high28 Ų2857.4 Ų57.417%0.17227%0.27CS..Hα-helixtrans-59.8-49177.3-54.40000111L52 H53 V54 Y58 F60 M110 I113L52-T56 PolarHBondContact O-N 3.36Å; L52-T56 PolarHBondContact O-OG1 2.77Å; H53-T56 WeakPolarHBondContact O-CB 3.35Å; H53-T56 PolarHBondContact O-N 3.26Å; V54-T56 VanDerWaalsContact C-N 3.34Å; V54-T56 PolarHBondContact O-N 3.01Å; T56-Y58 VanDerWaalsContact C-N 3.32Å; T56-Y58 PolarHBondContact O-N 2.85Å; T56-F60 WeakPolarHBondContact O-CB 3.39Å; T56-F60 PolarHBondContact O-N 3.45Å; T56-M110 HydrophobicContact CG2-CE 4.32Å; T56-I113 VanDerWaalsContact OG1-CG2 3.31Å; T56-I113 WeakPolarHBondContact OG1-CG2 3.37Å
57N92.5Very high92.5Very high73 Ų7351.9 Ų51.939%0.3925%0.249SC..Hα-helixtrans-65.8-37.7-179.5-69.2-21000111.7H53 V54 C61H53-N57 PolarHBondContact CD2-ND2 3.4Å; H53-N57 PolarHBondContact NE2-ND2 3.39Å; H53-N57 PolarHBondContact O-N 2.9Å; H53-N57 PolarHBondContact O-ND2 2.72Å; V54-N57 PolarHBondContact O-N 3.09Å; N57-C61 WeakPolarHBondContact O-CB 3.27Å; N57-C61 PolarHBondContact O-N 3.43Å; N57-C61 PolarHBondContact O-SG 3.02Å; N57-C61 VanDerWaalsContact O-SG 3.36Å
58Y93.8Very high92.5Very high56 Ų5652.2 Ų52.222%0.2225%0.25CS..Hα-helixtrans-59.4-56.5176.9176.7-96.7000111.4E3 M21 F26 V54 A55 T56 F60 C61 L62E3-Y58 WeakPolarHBondContact OE2-CE2 3.47Å; M21-Y58 HydrophobicContact CE-CE1 3.57Å; M21-Y58 HydrophobicContact SD-CE1 3.41Å; M21-Y58 WeakPolarHBondContact SD-CE1 3.27Å; M21-Y58 VanDerWaalsContact SD-CZ 3.59Å; M21-Y58 PolarHBondContact SD-OH 3.2Å; F26-Y58 HydrophobicContact CE2-CD1 4.43Å; F26-Y58 HydrophobicContact CZ-CD1 4.29Å; V54-Y58 WeakPolarHBondContact O-CB 3.3Å; V54-Y58 PolarHBondContact O-N 2.95Å; A55-Y58 PolarHBondContact O-N 3.24Å; T56-Y58 VanDerWaalsContact C-N 3.32Å; T56-Y58 PolarHBondContact O-N 2.85Å; Y58-F60 VanDerWaalsContact C-N 3.32Å; Y58-F60 PolarHBondContact O-N 2.9Å; Y58-C61 PolarHBondContact O-N 3.3Å; Y58-L62 HydrophobicContact CE1-CD2 3.8Å; Y58-L62 WeakPolarHBondContact O-CB 3.4Å; Y58-L62 PolarHBondContact O-N 3.42Å
59Y94.8Very high92.3Very high0 Ų055.1 Ų55.10%027%0.268CS..Hα-helixtrans-62.4-38.9179.6-87.5-74.4000112.4E18 M21 W22 F26 A55 C61 L62 I63 M106 H109 M110 I113E18-Y59 VanDerWaalsContact OE1-CE1 3.25Å; E18-Y59 WeakPolarHBondContact OE1-CE1 3.23Å; E18-Y59 PolarHBondContact OE1-OH 3.33Å; M21-Y59 HydrophobicContact CE-CE1 4.03Å; W22-Y59 WeakPolarHBondContact CB-OH 3.29Å; W22-Y59 AromaticContact CE3-CE2 3.98Å; W22-Y59 HydrophobicContact CE3-CE2 3.98Å; W22-Y59 HydrophobicContact CZ3-CE2 4.27Å; F26-Y59 AromaticContact CD2-CE2 3.82Å; F26-Y59 HydrophobicContact CD2-CE2 3.82Å; F26-Y59 HydrophobicContact CE2-CD2 4.45Å; F26-Y59 AromaticContact CE2-CE2 3.64Å; F26-Y59 HydrophobicContact CE2-CE2 3.64Å; F26-Y59 HydrophobicContact CZ-CE2 4.43Å; A55-Y59 WeakPolarHBondContact O-CD2 3.39Å; A55-Y59 PolarHBondContact O-N 3.34Å; Y59-C61 PolarHBondContact O-N 3.22Å; Y59-L62 PolarHBondContact O-N 3.04Å; Y59-I63 WeakPolarHBondContact O-CB 3.47Å; Y59-I63 VanDerWaalsContact O-CG1 3.29Å; Y59-I63 WeakPolarHBondContact O-CG1 3.42Å; Y59-I63 PolarHBondContact O-N 3.49Å; Y59-M106 HydrophobicContact CD1-CB 3.9Å; Y59-M106 HydrophobicContact CD1-CG 3.76Å; Y59-M106 HydrophobicContact CD1-SD 4.49Å; Y59-M106 HydrophobicContact CE1-CB 4.31Å; Y59-M106 HydrophobicContact CE1-CG 3.9Å; Y59-H109 HydrophobicContact CE1-CB 4.1Å; Y59-H109 HydrophobicContact CE2-CB 4.23Å; Y59-M110 HydrophobicContact CG-CG 4.3Å; Y59-I113 HydrophobicContact CD2-CD1 3.66Å; Y59-I113 HydrophobicContact CE2-CD1 4.08Å
60F92.6Very high92.2Very high90 Ų9053.8 Ų53.840%0.39527%0.265SS..Hα-helixtrans-61-43.3176.5-178.4-104.7000112.9T56 Y58 R64 M110T56-F60 WeakPolarHBondContact O-CB 3.39Å; T56-F60 PolarHBondContact O-N 3.45Å; Y58-F60 VanDerWaalsContact C-N 3.32Å; Y58-F60 PolarHBondContact O-N 2.9Å; F60-R64 VanDerWaalsContact CE1-NH1 3.28Å; F60-R64 PolarHBondContact O-N 2.87Å; F60-M110 HydrophobicContact CB-CE 4.38Å
61C93.9Very high92.1Very high63 Ų6350 Ų5043%0.42625%0.251SS..Hα-helixtrans-67.4-39.8175-74.70000112N57 Y58 Y59 R64 K65N57-C61 WeakPolarHBondContact O-CB 3.27Å; N57-C61 PolarHBondContact O-N 3.43Å; N57-C61 PolarHBondContact O-SG 3.02Å; N57-C61 VanDerWaalsContact O-SG 3.36Å; Y58-C61 PolarHBondContact O-N 3.3Å; Y59-C61 PolarHBondContact O-N 3.22Å; C61-R64 PolarHBondContact O-N 2.87Å; C61-K65 WeakPolarHBondContact O-CG 3.1Å; C61-K65 PolarHBondContact O-N 3.43Å; C61-K65 VanDerWaalsContact O-N 3.16Å
62L94.3Very high91.8Very high1 Ų150.6 Ų50.61%0.00527%0.265CS..Hα-helixtrans-66.8-43.8-179.4-173.857.1000111.9E3 I6 L7 M21 Y58 Y59 R64 K65 V66 M106E3-L62 HydrophobicContact CG-CD1 4.02Å; I6-L62 HydrophobicContact CD1-CD2 4.16Å; I6-L62 HydrophobicContact CG2-CD1 4.42Å; L7-L62 HydrophobicContact CD2-CD1 4.45Å; M21-L62 HydrophobicContact CE-CD2 4.22Å; Y58-L62 HydrophobicContact CE1-CD2 3.8Å; Y58-L62 WeakPolarHBondContact O-CB 3.4Å; Y58-L62 PolarHBondContact O-N 3.42Å; Y59-L62 PolarHBondContact O-N 3.04Å; L62-R64 VanDerWaalsContact C-N 3.28Å; L62-R64 PolarHBondContact O-N 3.01Å; L62-K65 PolarHBondContact O-N 3.35Å; L62-V66 HydrophobicContact CD1-CG2 4.09Å; L62-V66 HydrophobicContact CG-CG2 4.29Å; L62-V66 WeakPolarHBondContact O-CG2 3.45Å; L62-V66 PolarHBondContact O-N 3.03Å; L62-M106 HydrophobicContact CB-CE 4.49Å; L62-M106 HydrophobicContact CB-SD 4.38Å; L62-M106 HydrophobicContact CD1-CE 4.49Å; L62-M106 HydrophobicContact CD2-CE 3.33Å; L62-M106 HydrophobicContact CD2-SD 4.16Å; L62-M106 HydrophobicContact CG-CE 3.48Å; L62-M106 VanDerWaalsContact CG-CE 3.48Å; L62-M106 HydrophobicContact CG-SD 3.93Å
63I93.5Very high91.4Very high5 Ų555.4 Ų55.43%0.02629%0.29CS..Hα-helixtrans-53.2-47173.9-73.7168.7000110.6Y59 K65 V66 A67 L79 I103 M106 Y107 M110Y59-I63 WeakPolarHBondContact O-CB 3.47Å; Y59-I63 VanDerWaalsContact O-CG1 3.29Å; Y59-I63 WeakPolarHBondContact O-CG1 3.42Å; Y59-I63 PolarHBondContact O-N 3.49Å; I63-K65 VanDerWaalsContact C-N 3.31Å; I63-K65 PolarHBondContact O-N 3.5Å; I63-V66 PolarHBondContact O-N 3.43Å; I63-A67 WeakPolarHBondContact O-CB 3.13Å; I63-A67 PolarHBondContact O-N 3.48Å; I63-L79 HydrophobicContact CG2-CD2 3.65Å; I63-I103 HydrophobicContact CG1-CG2 4.48Å; I63-I103 HydrophobicContact CG2-CD1 4.29Å; I63-I103 HydrophobicContact CG2-CG1 4.32Å; I63-I103 HydrophobicContact CG2-CG2 4.12Å; I63-M106 HydrophobicContact CD1-CB 3.85Å; I63-M106 HydrophobicContact CG1-CB 3.61Å; I63-M106 HydrophobicContact CG1-CG 4.22Å; I63-M106 HydrophobicContact CG1-SD 3.65Å; I63-Y107 HydrophobicContact CD1-CD1 4.1Å; I63-Y107 HydrophobicContact CD1-CE1 3.9Å; I63-M110 HydrophobicContact CD1-CG 4.49Å; I63-M110 HydrophobicContact CD1-SD 3.42Å; I63-M110 WeakPolarHBondContact CD1-SD 3.33Å
64R93.1Very high91.1Very high134 Ų13450.9 Ų50.951%0.50627%0.269SS..Hα-helixtrans-64.9-32.3179-74177168.1178.9-5.8113.5F60 C61 L62 K68F60-R64 VanDerWaalsContact CE1-NH1 3.28Å; F60-R64 PolarHBondContact O-N 2.87Å; C61-R64 PolarHBondContact O-N 2.87Å; L62-R64 VanDerWaalsContact C-N 3.28Å; L62-R64 PolarHBondContact O-N 3.01Å; R64-K68 WeakPolarHBondContact O-CG 3.36Å
65K93.3Very high90.9Very high95 Ų9549.6 Ų49.641%0.41326%0.258SS..Hα-helixtrans-74.5-46.1177.4-71.8173176.9174.70110.8E3 L7 C61 L62 I63 K68E3-K65 IonicContact OE1-NZ 2.63Å; E3-K65 PolarHBondContact OE1-NZ 3.19Å; L7-K65 HydrophobicContact CD1-CB 4.31Å; L7-K65 HydrophobicContact CD1-CD 4.03Å; L7-K65 HydrophobicContact CD2-CB 3.96Å; C61-K65 WeakPolarHBondContact O-CG 3.1Å; C61-K65 PolarHBondContact O-N 3.43Å; C61-K65 VanDerWaalsContact O-N 3.16Å; L62-K65 PolarHBondContact O-N 3.35Å; I63-K65 VanDerWaalsContact C-N 3.31Å; I63-K65 PolarHBondContact O-N 3.5Å; K65-K68 PolarHBondContact O-N 3.3Å
66V92.1Very high90.4Very high1 Ų154.5 Ų54.51%0.00628%0.28CS..Hα-helixtrans-64.3-41177.9173.90000111.2I6 L7 L62 I63 K68 V69 F98 V99 M102 I103 M106I6-V66 HydrophobicContact CG2-CG2 4.02Å; L7-V66 HydrophobicContact CD2-CG2 4.02Å; L62-V66 HydrophobicContact CD1-CG2 4.09Å; L62-V66 HydrophobicContact CG-CG2 4.29Å; L62-V66 WeakPolarHBondContact O-CG2 3.45Å; L62-V66 PolarHBondContact O-N 3.03Å; I63-V66 PolarHBondContact O-N 3.43Å; V66-K68 PolarHBondContact O-N 2.93Å; V66-V69 VanDerWaalsContact O-CB 3.31Å; V66-V69 WeakPolarHBondContact O-CB 3.3Å; V66-V69 PolarHBondContact O-N 3.22Å; V66-F98 HydrophobicContact CG1-CE1 4.35Å; V66-V99 HydrophobicContact CG1-CG1 4.36Å; V66-M102 HydrophobicContact CG1-CB 3.93Å; V66-M102 HydrophobicContact CG1-CG 3.78Å; V66-M102 HydrophobicContact CG2-CG 4.17Å; V66-I103 HydrophobicContact CB-CG1 4.4Å; V66-I103 HydrophobicContact CG1-CD1 4.23Å; V66-I103 HydrophobicContact CG1-CG1 4.04Å; V66-M106 HydrophobicContact CG2-CE 4.14Å
67A91.4Very high89.8Confident0 Ų053.3 Ų53.30%027%0.273CS..Hα-helixtrans-56.9-36.6178.500000112.5I63 V69 G70 E75 V78 L79 I103I63-A67 WeakPolarHBondContact O-CB 3.13Å; I63-A67 PolarHBondContact O-N 3.48Å; A67-V69 VanDerWaalsContact C-N 3.28Å; A67-V69 PolarHBondContact O-N 3.5Å; A67-G70 PolarHBondContact O-N 3Å; A67-E75 HydrophobicContact CB-CG 4.07Å; A67-E75 WeakPolarHBondContact O-CB 3.43Å; A67-V78 HydrophobicContact CB-CG2 3.62Å; A67-L79 HydrophobicContact CB-CD1 3.93Å; A67-L79 HydrophobicContact CB-CD2 3.99Å; A67-L79 HydrophobicContact CB-CG 3.87Å; A67-I103 HydrophobicContact CB-CD1 3.82Å
68K91.1Very high89.6Confident144 Ų14450 Ų5063%0.62626%0.255SS*.THydrogen-bonded Turntrans-75.7-9.6178.5-70.9178.9178.5-167.30114.8R64 K65 V66 G70 E75R64-K68 WeakPolarHBondContact O-CG 3.36Å; K65-K68 PolarHBondContact O-N 3.3Å; V66-K68 PolarHBondContact O-N 2.93Å; K68-G70 VanDerWaalsContact C-N 3.32Å; K68-E75 WeakPolarHBondContact CG-OE1 3.42Å
69V89.3Confident89.2Confident63 Ų6350.4 Ų50.438%0.38226%0.261SS..THydrogen-bonded Turntrans-75.8-28.2174.1179.80000110.4V66 A67 V99V66-V69 VanDerWaalsContact O-CB 3.31Å; V66-V69 WeakPolarHBondContact O-CB 3.3Å; V66-V69 PolarHBondContact O-N 3.22Å; A67-V69 VanDerWaalsContact C-N 3.28Å; A67-V69 PolarHBondContact O-N 3.5Å; V69-V99 HydrophobicContact CB-CG2 4.34Å
70G86.1Confident88.2Confident14 Ų1452 Ų5214%0.14427%0.272CS..SBendtrans-84.9-176.3179.200000113.5A67 K68 D96A67-G70 PolarHBondContact O-N 3Å; K68-G70 VanDerWaalsContact C-N 3.32Å; G70-D96 VanDerWaalsContact CA-OD1 3.28Å; G70-D96 WeakPolarHBondContact CA-OD1 3.21Å
71S88.7Confident86.9Confident33 Ų3351.4 Ų51.423%0.23128%0.276CS..  trans-63.4160.2171.274.50000111.6L73 A74 E75 D96S71-L73 PolarHBondContact O-N 2.77Å; S71-L73 PolarHBondContact OG-N 3.39Å; S71-A74 PolarHBondContact O-N 2.8Å; S71-A74 PolarHBondContact OG-N 2.95Å; S71-A74 VanDerWaalsContact OG-N 3.11Å; S71-E75 PolarHBondContact O-N 3.18Å; S71-D96 VanDerWaalsContact CB-OD2 3.29Å; S71-D96 WeakPolarHBondContact CB-OD2 3.48Å; S71-D96 PolarHBondContact N-OD1 2.83Å; S71-D96 PolarHBondContact OG-OD1 2.99Å; S71-D96 PolarHBondContact OG-OD2 3.23Å
72A86.6Confident85.3Confident79 Ų7949.7 Ų49.765%0.65326%0.264SS*.Hα-helixtrans-57.5-31.6174.300000112.4E76A72-E76 WeakPolarHBondContact O-CB 3.47Å; A72-E76 PolarHBondContact O-N 3Å
73L83Confident83Confident101 Ų10152.6 Ų52.653%0.52928%0.282SS..Hα-helixtrans-68.9-43.1175.2179.364.4000111.2S71 T77S71-L73 PolarHBondContact O-N 2.77Å; S71-L73 PolarHBondContact OG-N 3.39Å; L73-T77 VanDerWaalsContact O-CB 3.25Å; L73-T77 WeakPolarHBondContact O-CB 3.31Å; L73-T77 PolarHBondContact O-N 3.43Å; L73-T77 PolarHBondContact O-OG1 2.96Å
74A85Confident80.7Confident0 Ų053.1 Ų53.10%029%0.286CS..Hα-helixtrans-64.4-45.6174.800000111.3S71 E76 T77 V78 D96S71-A74 PolarHBondContact O-N 2.8Å; S71-A74 PolarHBondContact OG-N 2.95Å; S71-A74 VanDerWaalsContact OG-N 3.11Å; A74-E76 PolarHBondContact O-N 3.13Å; A74-T77 WeakPolarHBondContact O-CB 3.33Å; A74-T77 PolarHBondContact O-N 2.88Å; A74-T77 VanDerWaalsContact O-N 3.08Å; A74-V78 WeakPolarHBondContact O-CG1 3.36Å; A74-V78 WeakPolarHBondContact O-CG2 3.48Å; A74-V78 PolarHBondContact O-N 3.13Å; A74-D96 HydrophobicContact CB-CB 3.89Å; A74-D96 VanDerWaalsContact CB-CG 3.41Å; A74-D96 WeakPolarHBondContact CB-OD1 3.27Å
75E87.7Confident78.6Confident61 Ų6147.7 Ų47.729%0.28527%0.267SS..Hα-helixtrans-56.6-49.4175.6-176.1174.8-173.100111.5A67 K68 S71 T77 L79A67-E75 HydrophobicContact CB-CG 4.07Å; A67-E75 WeakPolarHBondContact O-CB 3.43Å; K68-E75 WeakPolarHBondContact CG-OE1 3.42Å; S71-E75 PolarHBondContact O-N 3.18Å; E75-T77 VanDerWaalsContact C-N 3.28Å; E75-T77 PolarHBondContact O-N 2.97Å; E75-L79 HydrophobicContact CG-CD1 3.74Å; E75-L79 HydrophobicContact CG-CG 4.46Å; E75-L79 VanDerWaalsContact O-CB 3.31Å; E75-L79 WeakPolarHBondContact O-CB 3.38Å; E75-L79 VanDerWaalsContact O-CG 3.32Å; E75-L79 WeakPolarHBondContact O-CG 3.31Å; E75-L79 PolarHBondContact O-N 3.01Å; E75-L79 VanDerWaalsContact O-N 3.09Å
76E83.3Confident76.7Confident103 Ų10344.9 Ų44.948%0.48125%0.254SS..Hα-helixtrans-61.1-40.4175.7-177.7176-174.500111.1A72 A74 S80A72-E76 WeakPolarHBondContact O-CB 3.47Å; A72-E76 PolarHBondContact O-N 3Å; A74-E76 PolarHBondContact O-N 3.13Å; E76-S80 WeakPolarHBondContact O-CB 3.28Å; E76-S80 PolarHBondContact O-N 3.48Å; E76-S80 PolarHBondContact O-OG 3.03Å
77T80.5Confident74.9Confident4 Ų445.7 Ų45.73%0.02526%0.257CS..Hα-helixtrans-62.1-56-178.8-61.80000112.1L73 A74 E75 L79 S80 R86 Y92 L142L73-T77 VanDerWaalsContact O-CB 3.25Å; L73-T77 WeakPolarHBondContact O-CB 3.31Å; L73-T77 PolarHBondContact O-N 3.43Å; L73-T77 PolarHBondContact O-OG1 2.96Å; A74-T77 WeakPolarHBondContact O-CB 3.33Å; A74-T77 PolarHBondContact O-N 2.88Å; A74-T77 VanDerWaalsContact O-N 3.08Å; E75-T77 VanDerWaalsContact C-N 3.28Å; E75-T77 PolarHBondContact O-N 2.97Å; T77-L79 PolarHBondContact O-N 3.07Å; T77-S80 PolarHBondContact O-N 3.33Å; T77-S80 PolarHBondContact O-OG 3.12Å; T77-R86 VanDerWaalsContact CB-NH1 3.28Å; T77-R86 PolarHBondContact OG1-NH1 3.39Å; T77-Y92 WeakPolarHBondContact CG2-OH 3.43Å; T77-L142 HydrophobicContact CG2-CD2 4.25Å
78V86.3Confident72.9Confident2 Ų249.5 Ų49.51%0.01228%0.277CS..Hα-helixtrans-72.9-26.8-173.3-600000113A67 A74 V99 V100 I103 Y107 L142A67-V78 HydrophobicContact CB-CG2 3.62Å; A74-V78 WeakPolarHBondContact O-CG1 3.36Å; A74-V78 WeakPolarHBondContact O-CG2 3.48Å; A74-V78 PolarHBondContact O-N 3.13Å; V78-V99 HydrophobicContact CG1-CG1 4.35Å; V78-V99 HydrophobicContact CG2-CG1 4.43Å; V78-V100 HydrophobicContact CG1-CG2 4Å; V78-I103 HydrophobicContact CB-CB 4.33Å; V78-I103 HydrophobicContact CB-CD1 3.59Å; V78-I103 HydrophobicContact CB-CG2 4.03Å; V78-I103 HydrophobicContact CG1-CB 4.48Å; V78-I103 HydrophobicContact CG1-CD1 4.02Å; V78-I103 HydrophobicContact CG2-CD1 3.27Å; V78-Y107 PolarHBondContact O-OH 2.68Å; V78-L142 HydrophobicContact CG1-CD1 4.45Å; V78-L142 HydrophobicContact CG1-CD2 4.13Å
79L86.3Confident71.4Confident66 Ų6651 Ų5135%0.34628%0.283SS..Hα-helixtrans-93.9-13.9179-60.6-177.7000113.6I63 A67 E75 T77I63-L79 HydrophobicContact CG2-CD2 3.65Å; A67-L79 HydrophobicContact CB-CD1 3.93Å; A67-L79 HydrophobicContact CB-CD2 3.99Å; A67-L79 HydrophobicContact CB-CG 3.87Å; E75-L79 HydrophobicContact CG-CD1 3.74Å; E75-L79 HydrophobicContact CG-CG 4.46Å; E75-L79 VanDerWaalsContact O-CB 3.31Å; E75-L79 WeakPolarHBondContact O-CB 3.38Å; E75-L79 VanDerWaalsContact O-CG 3.32Å; E75-L79 WeakPolarHBondContact O-CG 3.31Å; E75-L79 PolarHBondContact O-N 3.01Å; E75-L79 VanDerWaalsContact O-N 3.09Å; T77-L79 PolarHBondContact O-N 3.07Å
80S73.9Confident70.3Confident32 Ų3250.6 Ų50.622%0.22428%0.281CS..SBendtrans-67.2143.2176.865.80000111.4E76 T77 P82 R86E76-S80 WeakPolarHBondContact O-CB 3.28Å; E76-S80 PolarHBondContact O-N 3.48Å; E76-S80 PolarHBondContact O-OG 3.03Å; T77-S80 PolarHBondContact O-N 3.33Å; T77-S80 PolarHBondContact O-OG 3.12Å; S80-P82 WeakPolarHBondContact O-CD 3.3Å; S80-R86 PolarHBondContact OG-NH2 3.35Å
81V66.3Low69.5Low78 Ų7856.6 Ų56.647%0.47331%0.31SS..  trans-64125.3161-178.10000106.2T83 Y138V81-T83 VanDerWaalsContact C-N 3.32Å; V81-T83 PolarHBondContact O-N 3.44Å; V81-Y138 HydrophobicContact CG1-CE1 4.2Å; V81-Y138 WeakPolarHBondContact CG1-OH 3.49Å; V81-Y138 VanDerWaalsContact CG2-OH 3.29Å; V81-Y138 WeakPolarHBondContact CG2-OH 3.47Å
82P58.9Low68.9Low27 Ų2757.3 Ų57.318%0.17531%0.308CS..  trans-59.6100170-17.631.4000107.5S80 Y138 S141S80-P82 WeakPolarHBondContact O-CD 3.3Å; P82-Y138 HydrophobicContact CG-CD1 3.53Å; P82-Y138 HydrophobicContact CG-CE1 3.95Å; P82-Y138 HydrophobicContact CG-CG 4.15Å; P82-S141 VanDerWaalsContact CG-OG 3.28Å; P82-S141 WeakPolarHBondContact CG-OG 3.31Å
83T46.5Very low68.5Low62 Ų6259.6 Ų59.638%0.3831%0.305SS..SBendtrans-73.2-20.3172.541.70000110.7V81 I438V81-T83 VanDerWaalsContact C-N 3.32Å; V81-T83 PolarHBondContact O-N 3.44Å; T83-I438 VanDerWaalsContact CB-O 3.31Å; T83-I438 WeakPolarHBondContact CB-O 3.31Å; T83-I438 WeakPolarHBondContact CG2-O 3.44Å; T83-I438 PolarHBondContact OG1-O 2.86Å
84S45.5Very low68.2Low16 Ų1659.6 Ų59.611%0.11231%0.314CS..SBendtrans-146.4142.4159.445.40000105.4R86S84-R86 PolarHBondContact O-N 2.9Å; S84-R86 VanDerWaalsContact O-N 3.16Å
85L48.4Very low67.9Low20 Ų2064.2 Ų64.211%0.10534%0.335CS..  trans-54.9123.8172.2-80.7143.2000108W87 Q137 L140 A423L85-W87 HydrophobicContact CB-CD2 4.12Å; L85-W87 HydrophobicContact CB-CG 4.06Å; L85-W87 HydrophobicContact CB-CZ2 3.92Å; L85-W87 HydrophobicContact CD1-CZ2 3.48Å; L85-W87 VanDerWaalsContact CD1-CZ2 3.48Å; L85-W87 HydrophobicContact CD2-CH2 4.34Å; L85-W87 HydrophobicContact CD2-CZ2 3.59Å; L85-W87 HydrophobicContact CG-CZ2 3.86Å; L85-W87 PolarHBondContact O-N 3.36Å; L85-Q137 WeakPolarHBondContact CD2-O 3.11Å; L85-L140 HydrophobicContact CD2-CB 4.07Å; L85-L140 HydrophobicContact CD2-CD2 4.25Å; L85-L140 HydrophobicContact CD2-CG 4.03Å; L85-A423 HydrophobicContact CB-CB 4.28Å; L85-A423 HydrophobicContact CD1-CB 3.63Å; L85-A423 VanDerWaalsContact CD1-O 3.27Å; L85-A423 WeakPolarHBondContact CD1-O 3.31Å; L85-A423 HydrophobicContact CG-CB 4.31Å
86R54.1Low67.9Low36 Ų3661.6 Ų61.614%0.13632%0.323CS..  trans-78.174.2-178.4-63.7-179.8-176.3-143.95.8109.2T77 S80 S84 N88 S141T77-R86 VanDerWaalsContact CB-NH1 3.28Å; T77-R86 PolarHBondContact OG1-NH1 3.39Å; S80-R86 PolarHBondContact OG-NH2 3.35Å; S84-R86 PolarHBondContact O-N 2.9Å; S84-R86 VanDerWaalsContact O-N 3.16Å; R86-N88 VanDerWaalsContact C-N 3.3Å; R86-N88 PolarHBondContact O-N 3.09Å; R86-S141 VanDerWaalsContact O-O 3.09Å
87W53.8Low68.1Low19 Ų1960.3 Ų60.37%0.07232%0.322CS..  trans-81.9-5.6-173-64.1108.2000114.4L85 L140 P144 F150 A423 F426L85-W87 HydrophobicContact CB-CD2 4.12Å; L85-W87 HydrophobicContact CB-CG 4.06Å; L85-W87 HydrophobicContact CB-CZ2 3.92Å; L85-W87 HydrophobicContact CD1-CZ2 3.48Å; L85-W87 VanDerWaalsContact CD1-CZ2 3.48Å; L85-W87 HydrophobicContact CD2-CH2 4.34Å; L85-W87 HydrophobicContact CD2-CZ2 3.59Å; L85-W87 HydrophobicContact CG-CZ2 3.86Å; L85-W87 PolarHBondContact O-N 3.36Å; W87-L140 HydrophobicContact CH2-CD1 3.56Å; W87-L140 HydrophobicContact CH2-CD2 3.52Å; W87-L140 HydrophobicContact CH2-CG 3.29Å; W87-L140 HydrophobicContact CZ2-CD2 3.97Å; W87-L140 HydrophobicContact CZ2-CG 3.95Å; W87-L140 HydrophobicContact CZ3-CD1 3.9Å; W87-L140 HydrophobicContact CZ3-CG 4.03Å; W87-P144 HydrophobicContact CD2-CB 4.01Å; W87-P144 HydrophobicContact CE3-CB 2.99Å; W87-P144 HydrophobicContact CE3-CG 4.27Å; W87-P144 HydrophobicContact CZ3-CB 3.29Å; W87-F150 HydrophobicContact CH2-CE1 4.37Å; W87-F150 AromaticContact CH2-CZ 3.86Å; W87-F150 HydrophobicContact CH2-CZ 3.86Å; W87-F150 HydrophobicContact CZ3-CZ 4.15Å; W87-A423 PolarHBondContact NE1-O 2.74Å; W87-F426 HydrophobicContact CB-CD1 3.14Å; W87-F426 HydrophobicContact CB-CE1 3.08Å; W87-F426 HydrophobicContact CB-CE2 4.45Å; W87-F426 HydrophobicContact CB-CG 3.91Å; W87-F426 HydrophobicContact CB-CZ 3.78Å; W87-F426 AromaticContact CD1-CD1 3.48Å; W87-F426 VanDerWaalsContact CD1-CD1 3.48Å; W87-F426 AromaticContact CD1-CG 3.4Å; W87-F426 VanDerWaalsContact CD1-CG 3.4Å; W87-F426 HydrophobicContact CD2-CB 4.48Å; W87-F426 AromaticContact CD2-CD1 3.89Å; W87-F426 HydrophobicContact CD2-CD1 3.89Å; W87-F426 HydrophobicContact CD2-CG 4.45Å; W87-F426 HydrophobicContact CE3-CD1 4.44Å; W87-F426 HydrophobicContact CG-CB 4.12Å; W87-F426 AromaticContact CG-CD1 3.25Å; W87-F426 HydrophobicContact CG-CD1 3.25Å; W87-F426 AromaticContact CG-CE1 3.79Å; W87-F426 HydrophobicContact CG-CE1 3.79Å; W87-F426 AromaticContact CG-CG 3.72Å; W87-F426 HydrophobicContact CG-CG 3.72Å; W87-F426 AromaticContact NE1-CG 3.96Å
88N50.4Low68.5Low80 Ų8061 Ų6143%0.42833%0.325SS..SBendtrans-83.8131.7171.3-74.3-12.6000109.1R86 T90 Q435R86-N88 VanDerWaalsContact C-N 3.3Å; R86-N88 PolarHBondContact O-N 3.09Å; N88-T90 PolarHBondContact O-N 3.32Å; N88-Q435 VanDerWaalsContact CB-OE1 3.3Å; N88-Q435 PolarHBondContact ND2-NE2 3.09Å; N88-Q435 PolarHBondContact ND2-OE1 3.28Å; N88-Q435 PolarHBondContact OD1-NE2 3.05Å
89K59.2Low68.7Low174 Ų17460.9 Ų60.976%0.75732%0.324SS*.  trans-55.2106.4169.6-166.6175.1-178.5178.40107.9
90T65.1Low68.8Low55 Ų5558.2 Ų58.234%0.33731%0.31SS..  trans-80.5120.2168.2-54.10000105.1N88 Y92N88-T90 PolarHBondContact O-N 3.32Å; T90-Y92 VanDerWaalsContact C-N 3.32Å; T90-Y92 HydrophobicContact CG2-CD1 4.16Å; T90-Y92 HydrophobicContact CG2-CE1 3.75Å; T90-Y92 HydrophobicContact CG2-CE2 4.24Å; T90-Y92 WeakPolarHBondContact O-CD2 3.4Å; T90-Y92 PolarHBondContact O-N 2.89Å
91D70.5Confident69.6Low141 Ų14158.3 Ų58.375%0.75431%0.308SS*.  trans-73.194.7174.9-70.1-33.5000107.8
92Y76.1Confident70.8Confident48 Ų4854.6 Ų54.619%0.18829%0.285CS..  trans-78.9146177.6-68.3-69.3000110.8T77 T90 D96 V100T77-Y92 WeakPolarHBondContact CG2-OH 3.43Å; T90-Y92 VanDerWaalsContact C-N 3.32Å; T90-Y92 HydrophobicContact CG2-CD1 4.16Å; T90-Y92 HydrophobicContact CG2-CE1 3.75Å; T90-Y92 HydrophobicContact CG2-CE2 4.24Å; T90-Y92 WeakPolarHBondContact O-CD2 3.4Å; T90-Y92 PolarHBondContact O-N 2.89Å; Y92-D96 HydrophobicContact CD1-CB 3.84Å; Y92-D96 HydrophobicContact CG-CB 4.14Å; Y92-V100 HydrophobicContact CD1-CG2 4.33Å; Y92-V100 HydrophobicContact CD2-CG2 4.04Å; Y92-V100 HydrophobicContact CE1-CG2 4.07Å; Y92-V100 HydrophobicContact CE2-CB 4.48Å; Y92-V100 HydrophobicContact CE2-CG1 4.27Å; Y92-V100 HydrophobicContact CE2-CG2 3.75Å; Y92-V100 HydrophobicContact CG-CG2 4.32Å
93E78.3Confident72.5Confident126 Ų12653.3 Ų53.359%0.58928%0.277SS*.  trans-61.4154.8164.5-64.2-175.1167.300110.1Q95 D96 V97E93-Q95 HydrophobicContact CB-CG 4.22Å; E93-Q95 PolarHBondContact O-N 3.39Å; E93-Q95 PolarHBondContact OE2-NE2 3.1Å; E93-D96 WeakPolarHBondContact O-CA 3.18Å; E93-D96 WeakPolarHBondContact O-CB 3.49Å; E93-D96 PolarHBondContact O-N 2.98Å; E93-V97 PolarHBondContact O-N 3.41Å
94S77.1Confident74.7Confident102 Ų10250.5 Ų50.571%0.71326%0.259SS*.Hα-helixtrans-52.9-33.4-175.2-51.60000114.1
95Q78Confident77Confident97 Ų9751.5 Ų51.545%0.45326%0.262SS..Hα-helixtrans-68.2-36.5175.562.8-176.3-9.100113.2E93E93-Q95 HydrophobicContact CB-CG 4.22Å; E93-Q95 PolarHBondContact O-N 3.39Å; E93-Q95 PolarHBondContact OE2-NE2 3.1Å
96D87.6Confident79.2Confident6 Ų650.5 Ų50.53%0.03226%0.257CS..Hα-helixtrans-80.1-31.4-178.1-74.3-13.8000111.3G70 S71 A74 Y92 E93 F98 V99 V100G70-D96 VanDerWaalsContact CA-OD1 3.28Å; G70-D96 WeakPolarHBondContact CA-OD1 3.21Å; S71-D96 VanDerWaalsContact CB-OD2 3.29Å; S71-D96 WeakPolarHBondContact CB-OD2 3.48Å; S71-D96 PolarHBondContact N-OD1 2.83Å; S71-D96 PolarHBondContact OG-OD1 2.99Å; S71-D96 PolarHBondContact OG-OD2 3.23Å; A74-D96 HydrophobicContact CB-CB 3.89Å; A74-D96 VanDerWaalsContact CB-CG 3.41Å; A74-D96 WeakPolarHBondContact CB-OD1 3.27Å; Y92-D96 HydrophobicContact CD1-CB 3.84Å; Y92-D96 HydrophobicContact CG-CB 4.14Å; E93-D96 WeakPolarHBondContact O-CA 3.18Å; E93-D96 WeakPolarHBondContact O-CB 3.49Å; E93-D96 PolarHBondContact O-N 2.98Å; D96-F98 VanDerWaalsContact C-N 3.26Å; D96-F98 PolarHBondContact O-N 2.99Å; D96-V99 PolarHBondContact O-N 2.78Å; D96-V99 VanDerWaalsContact O-N 3.12Å; D96-V100 VanDerWaalsContact O-CG2 3.31Å; D96-V100 WeakPolarHBondContact O-CG2 3.39Å; D96-V100 PolarHBondContact O-N 3.44Å
97V87.3Confident81.2Confident75 Ų7549.7 Ų49.746%0.45525%0.254SS..Hα-helixtrans-54.9-45.7172175.80000110.5E93 V99 V100 E101E93-V97 PolarHBondContact O-N 3.41Å; V97-V99 PolarHBondContact O-N 2.72Å; V97-V100 PolarHBondContact O-N 3.15Å; V97-E101 WeakPolarHBondContact O-CB 3.24Å; V97-E101 PolarHBondContact O-N 3.37Å
98F88.6Confident83.2Confident19 Ų1949.1 Ų49.18%0.08325%0.252CS..Hα-helixtrans-58.7-47.3175.6160.8-101.5000112.2P10 A14 V66 D96 V100 E101 M102P10-F98 HydrophobicContact CB-CD1 3.4Å; P10-F98 HydrophobicContact CB-CD2 4.03Å; P10-F98 HydrophobicContact CB-CE1 3.29Å; P10-F98 HydrophobicContact CB-CE2 3.92Å; P10-F98 HydrophobicContact CB-CG 3.77Å; P10-F98 HydrophobicContact CB-CZ 3.55Å; P10-F98 WeakPolarHBondContact O-CD2 3.44Å; P10-F98 WeakPolarHBondContact O-CE2 3.39Å; A14-F98 HydrophobicContact CB-CE2 3.49Å; A14-F98 VanDerWaalsContact CB-CE2 3.49Å; A14-F98 HydrophobicContact CB-CZ 3.84Å; V66-F98 HydrophobicContact CG1-CE1 4.35Å; D96-F98 VanDerWaalsContact C-N 3.26Å; D96-F98 PolarHBondContact O-N 2.99Å; F98-V100 VanDerWaalsContact C-N 3.33Å; F98-V100 PolarHBondContact O-N 3.05Å; F98-E101 PolarHBondContact O-N 3.43Å; F98-M102 HydrophobicContact CD2-CE 4.46Å; F98-M102 HydrophobicContact CE2-CB 4.27Å; F98-M102 HydrophobicContact CE2-CE 3.46Å; F98-M102 VanDerWaalsContact CE2-CE 3.46Å; F98-M102 HydrophobicContact CZ-CB 4.35Å; F98-M102 HydrophobicContact CZ-CE 3.91Å; F98-M102 HydrophobicContact CZ-CG 4.4Å; F98-M102 VanDerWaalsContact O-CB 3.26Å; F98-M102 WeakPolarHBondContact O-CB 3.18Å; F98-M102 PolarHBondContact O-N 2.91Å
99V90.4Very high85.3Confident0 Ų046.3 Ų46.30%024%0.236CC..Hα-helixtrans-61.8-44-178.5171.50000111V66 V69 V78 D96 V97 I103V66-V99 HydrophobicContact CG1-CG1 4.36Å; V69-V99 HydrophobicContact CB-CG2 4.34Å; V78-V99 HydrophobicContact CG1-CG1 4.35Å; V78-V99 HydrophobicContact CG2-CG1 4.43Å; D96-V99 PolarHBondContact O-N 2.78Å; D96-V99 VanDerWaalsContact O-N 3.12Å; V97-V99 PolarHBondContact O-N 2.72Å; V99-I103 HydrophobicContact CG1-CD1 3.8Å; V99-I103 WeakPolarHBondContact O-CB 3.34Å; V99-I103 WeakPolarHBondContact O-CG1 3.31Å; V99-I103 PolarHBondContact O-N 3Å
100V89.7Confident87Confident9 Ų939 Ų396%0.05521%0.205CC..Hα-helixtrans-64.6-46.6178.2173.50000111V78 Y92 D96 V97 F98 M102 I103 Y104 L142V78-V100 HydrophobicContact CG1-CG2 4Å; Y92-V100 HydrophobicContact CD1-CG2 4.33Å; Y92-V100 HydrophobicContact CD2-CG2 4.04Å; Y92-V100 HydrophobicContact CE1-CG2 4.07Å; Y92-V100 HydrophobicContact CE2-CB 4.48Å; Y92-V100 HydrophobicContact CE2-CG1 4.27Å; Y92-V100 HydrophobicContact CE2-CG2 3.75Å; Y92-V100 HydrophobicContact CG-CG2 4.32Å; D96-V100 VanDerWaalsContact O-CG2 3.31Å; D96-V100 WeakPolarHBondContact O-CG2 3.39Å; D96-V100 PolarHBondContact O-N 3.44Å; V97-V100 PolarHBondContact O-N 3.15Å; F98-V100 VanDerWaalsContact C-N 3.33Å; F98-V100 PolarHBondContact O-N 3.05Å; V100-M102 PolarHBondContact O-N 3.22Å; V100-I103 PolarHBondContact O-N 2.96Å; V100-Y104 VanDerWaalsContact O-CB 3.23Å; V100-Y104 WeakPolarHBondContact O-CB 3.48Å; V100-Y104 PolarHBondContact O-N 3.19Å; V100-L142 HydrophobicContact CG1-CB 4.1Å
101E90.4Very high88.4Confident35 Ų3536.3 Ų36.316%0.16419%0.189CC..Hα-helixtrans-60-45.7177.7-172.468.9-162.800111.7I15 V97 F98 Y104 H105 K143I15-E101 HydrophobicContact CD1-CG 3.86Å; V97-E101 WeakPolarHBondContact O-CB 3.24Å; V97-E101 PolarHBondContact O-N 3.37Å; F98-E101 PolarHBondContact O-N 3.43Å; E101-Y104 WeakPolarHBondContact O-CB 3.47Å; E101-Y104 PolarHBondContact O-N 3.44Å; E101-H105 PolarHBondContact O-N 3.23Å; E101-H105 IonicContact OE1-CE1 3.95Å; E101-H105 PolarHBondContact OE1-CE1 2.96Å; E101-H105 IonicContact OE1-NE2 3.38Å; E101-K143 IonicContact OE1-NZ 3.67Å; E101-K143 PolarHBondContact OE1-NZ 2.89Å; E101-K143 VanDerWaalsContact OE1-NZ 3.17Å; E101-K143 VanDerWaalsContact OE2-CD 3.24Å; E101-K143 WeakPolarHBondContact OE2-CD 3.35Å; E101-K143 WeakPolarHBondContact OE2-CE 3.38Å; E101-K143 IonicContact OE2-NZ 3.79Å; E101-K143 PolarHBondContact OE2-NZ 2.78Å
102M91.8Very high89.5Confident0 Ų029.9 Ų29.90%015%0.154CC..Hα-helixtrans-65.6-47-178.6-173.558.766.500111.6I6 A14 I15 E18 V66 F98 V100 Y104 H105 M106I6-M102 HydrophobicContact CG2-CE 4.29Å; I6-M102 HydrophobicContact CG2-SD 4.35Å; A14-M102 VanDerWaalsContact C-CE 3.49Å; A14-M102 HydrophobicContact CB-CE 3.78Å; I15-M102 HydrophobicContact CG1-CE 3.94Å; E18-M102 HydrophobicContact CB-CE 4.25Å; E18-M102 HydrophobicContact CB-SD 3.67Å; E18-M102 HydrophobicContact CG-SD 3.65Å; V66-M102 HydrophobicContact CG1-CB 3.93Å; V66-M102 HydrophobicContact CG1-CG 3.78Å; V66-M102 HydrophobicContact CG2-CG 4.17Å; F98-M102 HydrophobicContact CD2-CE 4.46Å; F98-M102 HydrophobicContact CE2-CB 4.27Å; F98-M102 HydrophobicContact CE2-CE 3.46Å; F98-M102 VanDerWaalsContact CE2-CE 3.46Å; F98-M102 HydrophobicContact CZ-CB 4.35Å; F98-M102 HydrophobicContact CZ-CE 3.91Å; F98-M102 HydrophobicContact CZ-CG 4.4Å; F98-M102 VanDerWaalsContact O-CB 3.26Å; F98-M102 WeakPolarHBondContact O-CB 3.18Å; F98-M102 PolarHBondContact O-N 2.91Å; V100-M102 PolarHBondContact O-N 3.22Å; M102-Y104 VanDerWaalsContact C-N 3.33Å; M102-Y104 PolarHBondContact O-N 3.37Å; M102-H105 PolarHBondContact O-N 3.36Å; M102-M106 HydrophobicContact CG-CE 3.45Å; M102-M106 VanDerWaalsContact CG-CE 3.45Å; M102-M106 HydrophobicContact CG-SD 4.31Å; M102-M106 VanDerWaalsContact O-CG 3.29Å; M102-M106 WeakPolarHBondContact O-CG 3.4Å; M102-M106 PolarHBondContact O-N 3.37Å; M102-M106 VanDerWaalsContact O-N 3.07Å; M102-M106 HydrophobicContact SD-CE 3.55Å; M102-M106 VanDerWaalsContact SD-CE 3.55Å
103I93.4Very high90.3Very high0 Ų027.6 Ų27.60%015%0.146CC..Hα-helixtrans-71.1-31.6-179-68171.1000111.5I63 V66 A67 V78 V99 V100 M106 Y107 L142I63-I103 HydrophobicContact CG1-CG2 4.48Å; I63-I103 HydrophobicContact CG2-CD1 4.29Å; I63-I103 HydrophobicContact CG2-CG1 4.32Å; I63-I103 HydrophobicContact CG2-CG2 4.12Å; V66-I103 HydrophobicContact CB-CG1 4.4Å; V66-I103 HydrophobicContact CG1-CD1 4.23Å; V66-I103 HydrophobicContact CG1-CG1 4.04Å; A67-I103 HydrophobicContact CB-CD1 3.82Å; V78-I103 HydrophobicContact CB-CB 4.33Å; V78-I103 HydrophobicContact CB-CD1 3.59Å; V78-I103 HydrophobicContact CB-CG2 4.03Å; V78-I103 HydrophobicContact CG1-CB 4.48Å; V78-I103 HydrophobicContact CG1-CD1 4.02Å; V78-I103 HydrophobicContact CG2-CD1 3.27Å; V99-I103 HydrophobicContact CG1-CD1 3.8Å; V99-I103 WeakPolarHBondContact O-CB 3.34Å; V99-I103 WeakPolarHBondContact O-CG1 3.31Å; V99-I103 PolarHBondContact O-N 3Å; V100-I103 PolarHBondContact O-N 2.96Å; I103-M106 PolarHBondContact O-N 2.87Å; I103-Y107 HydrophobicContact CG2-CD2 3.65Å; I103-Y107 HydrophobicContact CG2-CE2 3.35Å; I103-Y107 HydrophobicContact CG2-CG 4.49Å; I103-Y107 WeakPolarHBondContact O-CD2 3.31Å; I103-Y107 PolarHBondContact O-N 3.46Å; I103-L142 HydrophobicContact CB-CD1 4.43Å; I103-L142 HydrophobicContact CG2-CD1 4Å
104Y93.3Very high90.9Very high3 Ų322.4 Ų22.41%0.01212%0.122CC..Hα-helixtrans-52.9-53.5168.7160.3-97.8000111.6V100 E101 M102 M106 Y107 I108 A139 K143 E146 T148 P149V100-Y104 VanDerWaalsContact O-CB 3.23Å; V100-Y104 WeakPolarHBondContact O-CB 3.48Å; V100-Y104 PolarHBondContact O-N 3.19Å; E101-Y104 WeakPolarHBondContact O-CB 3.47Å; E101-Y104 PolarHBondContact O-N 3.44Å; M102-Y104 VanDerWaalsContact C-N 3.33Å; M102-Y104 PolarHBondContact O-N 3.37Å; Y104-M106 VanDerWaalsContact C-N 3.35Å; Y104-M106 PolarHBondContact O-N 2.86Å; Y104-Y107 PolarHBondContact O-N 3.15Å; Y104-I108 HydrophobicContact CE2-CG1 4.4Å; Y104-I108 PolarHBondContact O-N 2.98Å; Y104-A139 HydrophobicContact CD2-CB 3.84Å; Y104-A139 WeakPolarHBondContact CD2-O 3.25Å; Y104-A139 HydrophobicContact CE2-CB 4.08Å; Y104-K143 HydrophobicContact CD1-CD 3.72Å; Y104-K143 HydrophobicContact CD1-CG 4.42Å; Y104-K143 HydrophobicContact CD2-CB 3.73Å; Y104-K143 HydrophobicContact CD2-CD 4.01Å; Y104-K143 HydrophobicContact CD2-CG 3.84Å; Y104-K143 HydrophobicContact CE1-CD 4.1Å; Y104-K143 HydrophobicContact CE2-CB 3.81Å; Y104-K143 HydrophobicContact CE2-CD 4.34Å; Y104-K143 HydrophobicContact CE2-CG 4.33Å; Y104-K143 HydrophobicContact CG-CB 4.28Å; Y104-K143 HydrophobicContact CG-CD 3.69Å; Y104-K143 HydrophobicContact CG-CG 3.89Å; Y104-E146 HydrophobicContact CE2-CB 4.29Å; Y104-E146 WeakPolarHBondContact OH-CB 3.26Å; Y104-T148 WeakPolarHBondContact OH-CB 3.28Å; Y104-P149 HydrophobicContact CE2-CG 3.76Å
105H93.9Very high91.5Very high36 Ų3620.7 Ų20.717%0.16710%0.1CC..Hα-helixtrans-60.7-43.6177.4-68.2150.1000111.9E101 M102 Y107 I108 H109E101-H105 PolarHBondContact O-N 3.23Å; E101-H105 IonicContact OE1-CE1 3.95Å; E101-H105 PolarHBondContact OE1-CE1 2.96Å; E101-H105 IonicContact OE1-NE2 3.38Å; M102-H105 PolarHBondContact O-N 3.36Å; H105-Y107 VanDerWaalsContact C-N 3.3Å; H105-Y107 PolarHBondContact O-N 2.91Å; H105-I108 WeakPolarHBondContact O-CB 3.21Å; H105-I108 PolarHBondContact O-N 3.44Å; H105-I108 VanDerWaalsContact O-N 3.12Å; H105-H109 PolarHBondContact O-CD2 3.09Å; H105-H109 VanDerWaalsContact O-CG 3.31Å; H105-H109 PolarHBondContact O-N 3.07Å
106M95.3Very high92.1Very high0 Ų016.9 Ų16.90%08%0.082CC..Hα-helixtrans-61.2-37178.5-66.1178.8-178.300112.7E18 Y59 L62 I63 V66 M102 I103 Y104 H109 M110E18-M106 HydrophobicContact CG-CE 3.96Å; Y59-M106 HydrophobicContact CD1-CB 3.9Å; Y59-M106 HydrophobicContact CD1-CG 3.76Å; Y59-M106 HydrophobicContact CD1-SD 4.49Å; Y59-M106 HydrophobicContact CE1-CB 4.31Å; Y59-M106 HydrophobicContact CE1-CG 3.9Å; L62-M106 HydrophobicContact CB-CE 4.49Å; L62-M106 HydrophobicContact CB-SD 4.38Å; L62-M106 HydrophobicContact CD1-CE 4.49Å; L62-M106 HydrophobicContact CD2-CE 3.33Å; L62-M106 HydrophobicContact CD2-SD 4.16Å; L62-M106 HydrophobicContact CG-CE 3.48Å; L62-M106 VanDerWaalsContact CG-CE 3.48Å; L62-M106 HydrophobicContact CG-SD 3.93Å; I63-M106 HydrophobicContact CD1-CB 3.85Å; I63-M106 HydrophobicContact CG1-CB 3.61Å; I63-M106 HydrophobicContact CG1-CG 4.22Å; I63-M106 HydrophobicContact CG1-SD 3.65Å; V66-M106 HydrophobicContact CG2-CE 4.14Å; M102-M106 HydrophobicContact CG-CE 3.45Å; M102-M106 VanDerWaalsContact CG-CE 3.45Å; M102-M106 HydrophobicContact CG-SD 4.31Å; M102-M106 VanDerWaalsContact O-CG 3.29Å; M102-M106 WeakPolarHBondContact O-CG 3.4Å; M102-M106 PolarHBondContact O-N 3.37Å; M102-M106 VanDerWaalsContact O-N 3.07Å; M102-M106 HydrophobicContact SD-CE 3.55Å; M102-M106 VanDerWaalsContact SD-CE 3.55Å; I103-M106 PolarHBondContact O-N 2.87Å; Y104-M106 VanDerWaalsContact C-N 3.35Å; Y104-M106 PolarHBondContact O-N 2.86Å; M106-H109 PolarHBondContact O-N 2.71Å; M106-M110 WeakPolarHBondContact O-CB 3.36Å; M106-M110 VanDerWaalsContact O-CG 3.32Å; M106-M110 WeakPolarHBondContact O-CG 3.48Å; M106-M110 PolarHBondContact O-N 3.06Å
107Y95.2Very high92.1Very high18 Ų1820.6 Ų20.67%0.07110%0.095CC..Hα-helixtrans-67-38.8174.6-79.9-42.8000112.9I63 V78 I103 Y104 H105 H109 M110 G111 L135 Y138 L142I63-Y107 HydrophobicContact CD1-CD1 4.1Å; I63-Y107 HydrophobicContact CD1-CE1 3.9Å; V78-Y107 PolarHBondContact O-OH 2.68Å; I103-Y107 HydrophobicContact CG2-CD2 3.65Å; I103-Y107 HydrophobicContact CG2-CE2 3.35Å; I103-Y107 HydrophobicContact CG2-CG 4.49Å; I103-Y107 WeakPolarHBondContact O-CD2 3.31Å; I103-Y107 PolarHBondContact O-N 3.46Å; Y104-Y107 PolarHBondContact O-N 3.15Å; H105-Y107 VanDerWaalsContact C-N 3.3Å; H105-Y107 PolarHBondContact O-N 2.91Å; Y107-H109 VanDerWaalsContact C-N 3.34Å; Y107-M110 PolarHBondContact O-N 2.89Å; Y107-G111 PolarHBondContact O-N 2.89Å; Y107-L135 HydrophobicContact CD1-CD2 3.84Å; Y107-L135 HydrophobicContact CE1-CD2 4.28Å; Y107-Y138 HydrophobicContact CD1-CD2 4.18Å; Y107-Y138 AromaticContact CE1-CD2 3.72Å; Y107-Y138 HydrophobicContact CE1-CD2 3.72Å; Y107-Y138 HydrophobicContact CE2-CD2 4.22Å; Y107-Y138 AromaticContact CZ-CD2 3.74Å; Y107-L142 HydrophobicContact CD2-CD1 3.87Å; Y107-L142 HydrophobicContact CE2-CD1 4Å
108I95.3Very high92Very high8 Ų818 Ų184%0.0418%0.08CC..Hα-helixtrans-58.1-49171.1-63.4-60.3000110.3Y104 H105 G111 D112 Y136 A139 T148 P149Y104-I108 HydrophobicContact CE2-CG1 4.4Å; Y104-I108 PolarHBondContact O-N 2.98Å; H105-I108 WeakPolarHBondContact O-CB 3.21Å; H105-I108 PolarHBondContact O-N 3.44Å; H105-I108 VanDerWaalsContact O-N 3.12Å; I108-G111 PolarHBondContact O-N 2.67Å; I108-G111 VanDerWaalsContact O-N 3.17Å; I108-D112 PolarHBondContact O-N 3.44Å; I108-Y136 HydrophobicContact CD1-CD1 3.99Å; I108-Y136 WeakPolarHBondContact O-CE1 3.34Å; I108-A139 HydrophobicContact CD1-CB 3.51Å; I108-A139 HydrophobicContact CG1-CB 3.9Å; I108-T148 HydrophobicContact CD1-CG2 4.42Å; I108-T148 HydrophobicContact CG2-CG2 4.36Å; I108-P149 HydrophobicContact CD1-CB 4.15Å; I108-P149 HydrophobicContact CD1-CG 4.02Å
109H95.7Very high91.8Very high20 Ų2019.1 Ų19.19%0.0939%0.093CC..Hα-helixtrans-66.3-39.7-178.3-63.4-31.9000113E18 W22 Y59 H105 M106 Y107 G111 D112 I113E18-H109 IonicContact OE1-CD2 2.94Å; E18-H109 PolarHBondContact OE1-CD2 2.76Å; E18-H109 IonicContact OE1-NE2 3.68Å; E18-H109 IonicContact OE2-CD2 2.61Å; E18-H109 IonicContact OE2-NE2 3.98Å; E18-H109 PolarHBondContact OE2-NE2 3.14Å; W22-H109 AromaticContact CD1-CE1 3.27Å; W22-H109 AromaticContact CD1-ND1 3.57Å; W22-H109 AromaticContact CD1-NE2 3.89Å; W22-H109 HydrophobicContact CD2-CB 4.02Å; W22-H109 AromaticContact CD2-CE1 3.74Å; W22-H109 AromaticContact CD2-CG 3.52Å; W22-H109 AromaticContact CD2-ND1 3.28Å; W22-H109 VanDerWaalsContact CD2-ND1 3.28Å; W22-H109 AromaticContact CE2-CE1 3.78Å; W22-H109 AromaticContact CE2-CG 3.91Å; W22-H109 AromaticContact CE2-ND1 3.22Å; W22-H109 HydrophobicContact CE3-CB 3.65Å; W22-H109 AromaticContact CE3-CG 3.68Å; W22-H109 AromaticContact CE3-ND1 3.87Å; W22-H109 AromaticContact CG-CD2 3.95Å; W22-H109 AromaticContact CG-CE1 3.41Å; W22-H109 VanDerWaalsContact CG-CE1 3.41Å; W22-H109 AromaticContact CG-CG 3.83Å; W22-H109 AromaticContact CG-ND1 3.5Å; W22-H109 AromaticContact CG-NE2 3.7Å; W22-H109 HydrophobicContact CH2-CB 4.13Å; W22-H109 HydrophobicContact CZ2-CB 4.47Å; W22-H109 AromaticContact CZ2-ND1 3.75Å; W22-H109 HydrophobicContact CZ3-CB 3.72Å; W22-H109 AromaticContact NE1-CE1 3.49Å; W22-H109 PolarHBondContact NE1-CE1 3.21Å; W22-H109 AromaticContact NE1-ND1 3.4Å; W22-H109 PolarHBondContact NE1-ND1 3.12Å; Y59-H109 HydrophobicContact CE1-CB 4.1Å; Y59-H109 HydrophobicContact CE2-CB 4.23Å; H105-H109 PolarHBondContact O-CD2 3.09Å; H105-H109 VanDerWaalsContact O-CG 3.31Å; H105-H109 PolarHBondContact O-N 3.07Å; M106-H109 PolarHBondContact O-N 2.71Å; Y107-H109 VanDerWaalsContact C-N 3.34Å; H109-G111 VanDerWaalsContact C-N 3.31Å; H109-G111 PolarHBondContact O-N 3.09Å; H109-D112 PolarHBondContact O-N 2.9Å; H109-I113 VanDerWaalsContact O-CG1 3.3Å; H109-I113 WeakPolarHBondContact O-CG1 3.26Å; H109-I113 PolarHBondContact O-N 3.23Å
110M95Very high91.5Very high20 Ų2019.4 Ų19.410%0.09910%0.095CC..Hα-helixtrans-61.3-40.6172.1-74.6-169.67300111.8T56 Y59 F60 I63 M106 Y107 D112 I113 V114 L135T56-M110 HydrophobicContact CG2-CE 4.32Å; Y59-M110 HydrophobicContact CG-CG 4.3Å; F60-M110 HydrophobicContact CB-CE 4.38Å; I63-M110 HydrophobicContact CD1-CG 4.49Å; I63-M110 HydrophobicContact CD1-SD 3.42Å; I63-M110 WeakPolarHBondContact CD1-SD 3.33Å; M106-M110 WeakPolarHBondContact O-CB 3.36Å; M106-M110 VanDerWaalsContact O-CG 3.32Å; M106-M110 WeakPolarHBondContact O-CG 3.48Å; M106-M110 PolarHBondContact O-N 3.06Å; Y107-M110 PolarHBondContact O-N 2.89Å; M110-D112 VanDerWaalsContact C-N 3.34Å; M110-I113 PolarHBondContact O-N 3.41Å; M110-V114 WeakPolarHBondContact O-CG2 3.16Å; M110-V114 PolarHBondContact O-N 3.47Å; M110-V114 VanDerWaalsContact O-N 3.12Å; M110-L135 HydrophobicContact CB-CD1 3.92Å; M110-L135 HydrophobicContact CB-CD2 4.03Å; M110-L135 HydrophobicContact CB-CG 4.5Å; M110-L135 HydrophobicContact CE-CD2 4.41Å; M110-L135 HydrophobicContact SD-CD2 4.44Å
111G93.8Very high91Very high0 Ų022.8 Ų22.80%011%0.107CC..Hα-helixtrans-60.7-4417400000112Y107 I108 H109 V114 R115 Y136Y107-G111 PolarHBondContact O-N 2.89Å; I108-G111 PolarHBondContact O-N 2.67Å; I108-G111 VanDerWaalsContact O-N 3.17Å; H109-G111 VanDerWaalsContact C-N 3.31Å; H109-G111 PolarHBondContact O-N 3.09Å; G111-V114 WeakPolarHBondContact O-CB 3.41Å; G111-V114 PolarHBondContact O-N 3.24Å; G111-R115 PolarHBondContact O-N 3.13Å; G111-Y136 PolarHBondContact O-OH 2.98Å
112D93.8Very high90Very high5 Ų525.4 Ų25.43%0.02713%0.127CC..Hα-helixtrans-64.6-39.5177.1-75.4-17.9000112.3W22 I108 H109 M110 V114 R115 Y116 Y136 R152W22-D112 HydrophobicContact CH2-CB 3.68Å; W22-D112 HydrophobicContact CZ2-CB 3.72Å; I108-D112 PolarHBondContact O-N 3.44Å; H109-D112 PolarHBondContact O-N 2.9Å; M110-D112 VanDerWaalsContact C-N 3.34Å; D112-V114 VanDerWaalsContact C-N 3.31Å; D112-V114 PolarHBondContact O-N 2.87Å; D112-R115 WeakPolarHBondContact O-CB 3.41Å; D112-R115 PolarHBondContact O-N 3.26Å; D112-R115 VanDerWaalsContact O-N 3.13Å; D112-R115 IonicContact OD1-NH1 3.78Å; D112-Y116 HydrophobicContact CB-CE2 4.36Å; D112-Y116 VanDerWaalsContact O-CD2 3.25Å; D112-Y116 WeakPolarHBondContact O-CD2 3.39Å; D112-Y116 PolarHBondContact O-N 3.17Å; D112-Y136 WeakPolarHBondContact CA-OH 3.35Å; D112-Y136 PolarHBondContact N-OH 2.7Å; D112-Y136 VanDerWaalsContact N-OH 3.13Å; D112-Y136 PolarHBondContact OD1-OH 2.93Å; D112-R152 VanDerWaalsContact CG-NH1 3.35Å; D112-R152 WeakPolarHBondContact OD1-CD 3.09Å; D112-R152 IonicContact OD1-CZ 3.15Å; D112-R152 IonicContact OD1-NH1 2.78Å; D112-R152 PolarHBondContact OD1-NH1 3.17Å; D112-R152 IonicContact OD2-CZ 2.68Å; D112-R152 IonicContact OD2-NH1 3.58Å; D112-R152 PolarHBondContact OD2-NH1 3.34Å
113I93.3Very high88.6Confident1 Ų131.5 Ų31.51%0.00516%0.164CC..Hα-helixtrans-58-44.5173-71164.6000110.7W22 L52 A55 T56 Y59 H109 M110 R115 Y116 R117W22-I113 HydrophobicContact CH2-CG1 4.12Å; W22-I113 HydrophobicContact CZ3-CD1 4.11Å; W22-I113 HydrophobicContact CZ3-CG1 3.86Å; L52-I113 HydrophobicContact CB-CG2 4.44Å; L52-I113 HydrophobicContact CD2-CG2 3.95Å; A55-I113 HydrophobicContact CB-CD1 3.74Å; A55-I113 HydrophobicContact CB-CG1 4.31Å; T56-I113 VanDerWaalsContact OG1-CG2 3.31Å; T56-I113 WeakPolarHBondContact OG1-CG2 3.37Å; Y59-I113 HydrophobicContact CD2-CD1 3.66Å; Y59-I113 HydrophobicContact CE2-CD1 4.08Å; H109-I113 VanDerWaalsContact O-CG1 3.3Å; H109-I113 WeakPolarHBondContact O-CG1 3.26Å; H109-I113 PolarHBondContact O-N 3.23Å; M110-I113 PolarHBondContact O-N 3.41Å; I113-R115 VanDerWaalsContact C-N 3.32Å; I113-R115 PolarHBondContact O-N 2.87Å; I113-Y116 PolarHBondContact O-N 2.89Å; I113-R117 WeakPolarHBondContact O-CG 3.4Å; I113-R117 PolarHBondContact O-N 2.89Å
114V90.3Very high86.9Confident17 Ų1734.2 Ų34.210%0.10318%0.181CC..Hα-helixtrans-63.7-39.2176.8175.50000111M110 G111 D112 R117 S118 A128 T131 A132 L135M110-V114 WeakPolarHBondContact O-CG2 3.16Å; M110-V114 PolarHBondContact O-N 3.47Å; M110-V114 VanDerWaalsContact O-N 3.12Å; G111-V114 WeakPolarHBondContact O-CB 3.41Å; G111-V114 PolarHBondContact O-N 3.24Å; D112-V114 VanDerWaalsContact C-N 3.31Å; D112-V114 PolarHBondContact O-N 2.87Å; V114-R117 WeakPolarHBondContact O-CB 3.33Å; V114-R117 PolarHBondContact O-N 3.45Å; V114-S118 PolarHBondContact O-N 3.34Å; V114-A128 HydrophobicContact CG1-CB 3.82Å; V114-A128 WeakPolarHBondContact CG1-O 3.18Å; V114-T131 HydrophobicContact CG1-CG2 4.41Å; V114-T131 HydrophobicContact CG2-CG2 4.05Å; V114-A132 HydrophobicContact CB-CB 4.14Å; V114-A132 HydrophobicContact CG1-CB 3.85Å; V114-L135 HydrophobicContact CG2-CD1 3.91Å
115R89.4Confident85Confident66 Ų6635.8 Ų35.825%0.24919%0.191CC..Hα-helixtrans-63.3-44.3173.6-73.3178.867.8-151.53.7112.6G111 D112 I113 R117 S118 A119 A132 Y136 L156G111-R115 PolarHBondContact O-N 3.13Å; D112-R115 WeakPolarHBondContact O-CB 3.41Å; D112-R115 PolarHBondContact O-N 3.26Å; D112-R115 VanDerWaalsContact O-N 3.13Å; D112-R115 IonicContact OD1-NH1 3.78Å; I113-R115 VanDerWaalsContact C-N 3.32Å; I113-R115 PolarHBondContact O-N 2.87Å; R115-R117 VanDerWaalsContact C-N 3.31Å; R115-R117 PolarHBondContact O-N 3.44Å; R115-S118 WeakPolarHBondContact O-CB 3.42Å; R115-S118 PolarHBondContact O-N 3.28Å; R115-S118 VanDerWaalsContact O-N 3.13Å; R115-A119 PolarHBondContact O-N 3.24Å; R115-A132 HydrophobicContact CG-CB 4.27Å; R115-Y136 WeakPolarHBondContact CD-OH 3.21Å; R115-L156 HydrophobicContact CG-CD1 4.09Å
116Y90.2Very high83Confident16 Ų1642.9 Ų42.96%0.06322%0.218CC..Hα-helixtrans-59.6-42.7175.5-65.4-45.1000111.6W22 F30 D31 L52 D112 I113 S118 A119 I120W22-Y116 AromaticContact CH2-CE2 3.86Å; W22-Y116 HydrophobicContact CH2-CE2 3.86Å; W22-Y116 HydrophobicContact CZ2-CE2 4.13Å; F30-Y116 HydrophobicContact CB-CD1 4.08Å; F30-Y116 HydrophobicContact CB-CD2 3.63Å; F30-Y116 HydrophobicContact CB-CE1 4.27Å; F30-Y116 HydrophobicContact CB-CE2 3.84Å; F30-Y116 HydrophobicContact CB-CG 3.78Å; F30-Y116 HydrophobicContact CD2-CD2 4.45Å; F30-Y116 HydrophobicContact CG-CD2 4.25Å; D31-Y116 WeakPolarHBondContact OD1-CE1 3.26Å; D31-Y116 PolarHBondContact OD1-OH 3.07Å; L52-Y116 HydrophobicContact CD2-CD2 4.24Å; D112-Y116 HydrophobicContact CB-CE2 4.36Å; D112-Y116 VanDerWaalsContact O-CD2 3.25Å; D112-Y116 WeakPolarHBondContact O-CD2 3.39Å; D112-Y116 PolarHBondContact O-N 3.17Å; I113-Y116 PolarHBondContact O-N 2.89Å; Y116-S118 VanDerWaalsContact C-N 3.29Å; Y116-S118 PolarHBondContact O-N 3.34Å; Y116-A119 PolarHBondContact O-N 3.47Å; Y116-I120 WeakPolarHBondContact O-CB 3.43Å; Y116-I120 VanDerWaalsContact O-CG1 3.27Å; Y116-I120 WeakPolarHBondContact O-CG1 3.5Å; Y116-I120 PolarHBondContact O-N 2.89Å
117R88.3Confident81.3Confident85 Ų8552.7 Ų52.732%0.32125%0.254SS..Hα-helixtrans-57.9-43.5174.9-69.2173.967.8165.30.2111.6M49 L52 I113 V114 R115 I120 Y121M49-R117 HydrophobicContact CE-CB 4.27Å; M49-R117 HydrophobicContact CE-CG 4.17Å; M49-R117 HydrophobicContact SD-CB 4.2Å; M49-R117 HydrophobicContact SD-CG 4.11Å; L52-R117 HydrophobicContact CB-CG 3.74Å; L52-R117 HydrophobicContact CD1-CB 4.44Å; L52-R117 HydrophobicContact CD1-CG 3.65Å; L52-R117 HydrophobicContact CG-CG 4.16Å; I113-R117 WeakPolarHBondContact O-CG 3.4Å; I113-R117 PolarHBondContact O-N 2.89Å; V114-R117 WeakPolarHBondContact O-CB 3.33Å; V114-R117 PolarHBondContact O-N 3.45Å; R115-R117 VanDerWaalsContact C-N 3.31Å; R115-R117 PolarHBondContact O-N 3.44Å; R117-I120 PolarHBondContact O-N 3.27Å; R117-Y121 PolarHBondContact O-N 3.05Å
118S83.8Confident80Confident19 Ų1952.3 Ų52.313%0.13326%0.255CS..Hα-helixtrans-64.6-40.4177.6-171.10000112.9V114 R115 Y116 Y121 P122 V125V114-S118 PolarHBondContact O-N 3.34Å; R115-S118 WeakPolarHBondContact O-CB 3.42Å; R115-S118 PolarHBondContact O-N 3.28Å; R115-S118 VanDerWaalsContact O-N 3.13Å; Y116-S118 VanDerWaalsContact C-N 3.29Å; Y116-S118 PolarHBondContact O-N 3.34Å; S118-Y121 CarbonylContact O-C 3.29Å; S118-Y121 VanDerWaalsContact O-C 3.29Å; S118-P122 WeakPolarHBondContact O-CA 3.08Å; S118-V125 WeakPolarHBondContact OG-CA 3.45Å; S118-V125 VanDerWaalsContact OG-CG2 3.23Å; S118-V125 WeakPolarHBondContact OG-CG2 3.04Å
119A84.4Confident79.2Confident44 Ų4453 Ų5336%0.36426%0.257SS..Hα-helixtrans-69.5-36.6179.200000112.3R115 Y116R115-A119 PolarHBondContact O-N 3.24Å; Y116-A119 PolarHBondContact O-N 3.47Å
120I85.3Confident78.6Confident5 Ų555.3 Ų55.33%0.02627%0.274CS..Hα-helixtrans-74-38.8179.4-67.9174.3000111.5I33 L45 A48 M49 L52 Y116 R117I33-I120 HydrophobicContact CG2-CD1 3.71Å; I33-I120 HydrophobicContact CG2-CG1 4.07Å; L45-I120 HydrophobicContact CB-CG2 4.15Å; L45-I120 HydrophobicContact CD2-CG2 3.78Å; A48-I120 HydrophobicContact CB-CD1 3.99Å; M49-I120 HydrophobicContact CG-CG2 4.09Å; M49-I120 HydrophobicContact SD-CB 4.46Å; M49-I120 HydrophobicContact SD-CG2 4.18Å; L52-I120 HydrophobicContact CD1-CD1 3.6Å; Y116-I120 WeakPolarHBondContact O-CB 3.43Å; Y116-I120 VanDerWaalsContact O-CG1 3.27Å; Y116-I120 WeakPolarHBondContact O-CG1 3.5Å; Y116-I120 PolarHBondContact O-N 2.89Å; R117-I120 PolarHBondContact O-N 3.27Å
121Y79.6Confident78.2Confident81 Ų8157.7 Ų57.732%0.31829%0.29SS..  trans-125.488.6175.6-84.2-82.8000111.5L45 M49 R117 S118 T123 V124L45-Y121 HydrophobicContact CB-CE2 4.11Å; M49-Y121 HydrophobicContact CE-CD2 4.47Å; M49-Y121 HydrophobicContact CG-CD2 3.5Å; M49-Y121 VanDerWaalsContact CG-CD2 3.5Å; M49-Y121 HydrophobicContact CG-CE2 3.54Å; M49-Y121 HydrophobicContact SD-CD2 3.87Å; R117-Y121 PolarHBondContact O-N 3.05Å; S118-Y121 CarbonylContact O-C 3.29Å; S118-Y121 VanDerWaalsContact O-C 3.29Å; Y121-T123 PolarHBondContact O-N 3.27Å; Y121-T123 VanDerWaalsContact O-N 3.08Å; Y121-V124 WeakPolarHBondContact O-CB 3.34Å; Y121-V124 PolarHBondContact O-N 3.45Å
122P68.6Low78.1Confident89 Ų8957.8 Ų57.858%0.57829%0.29SS*.G310 helixtrans-61.8-20.2-177.8-25.834.9000114.8S118 V124 V125S118-P122 WeakPolarHBondContact O-CA 3.08Å; P122-V124 PolarHBondContact O-N 3.15Å; P122-V125 VanDerWaalsContact CA-CG2 3.45Å; P122-V125 HydrophobicContact CB-CG2 4Å; P122-V125 WeakPolarHBondContact O-CB 3.47Å; P122-V125 WeakPolarHBondContact O-CG2 3.39Å; P122-V125 PolarHBondContact O-N 2.9Å
123T63Low77.8Confident128 Ų12859.2 Ų59.279%0.78530%0.297SS*.G310 helixtrans-60.6-13.6173.654.50000112.9Y121Y121-T123 PolarHBondContact O-N 3.27Å; Y121-T123 VanDerWaalsContact O-N 3.08Å
124V56.8Low77.5Confident57 Ų5763.7 Ų63.735%0.34532%0.317SS..G310 helixtrans-104.6-0.1178.6-162.60000112.2Y121 P122 Y126 R127 A128Y121-V124 WeakPolarHBondContact O-CB 3.34Å; Y121-V124 PolarHBondContact O-N 3.45Å; P122-V124 PolarHBondContact O-N 3.15Å; V124-Y126 PolarHBondContact O-N 3.09Å; V124-R127 HydrophobicContact CG1-CB 3.93Å; V124-R127 CarbonylContact O-C 3.57Å; V124-R127 WeakPolarHBondContact O-CA 3.48Å; V124-R127 WeakPolarHBondContact O-CB 3.35Å; V124-R127 PolarHBondContact O-N 3.32Å; V124-A128 PolarHBondContact O-N 3.09Å
125V52.8Low77.5Confident37 Ų3763.8 Ų63.822%0.22432%0.316CS..Hα-helixtrans-54.8-47.8-170.7170.20000112.8S118 P122 R127 A128 Y129 V160S118-V125 WeakPolarHBondContact OG-CA 3.45Å; S118-V125 VanDerWaalsContact OG-CG2 3.23Å; S118-V125 WeakPolarHBondContact OG-CG2 3.04Å; P122-V125 VanDerWaalsContact CA-CG2 3.45Å; P122-V125 HydrophobicContact CB-CG2 4Å; P122-V125 WeakPolarHBondContact O-CB 3.47Å; P122-V125 WeakPolarHBondContact O-CG2 3.39Å; P122-V125 PolarHBondContact O-N 2.9Å; V125-R127 PolarHBondContact O-N 3.01Å; V125-A128 PolarHBondContact O-N 3.42Å; V125-Y129 PolarHBondContact O-N 2.89Å; V125-Y129 VanDerWaalsContact O-N 3.16Å; V125-V160 HydrophobicContact CG1-CG1 4.27Å
126Y52.6Low77.7Confident185 Ų18560.6 Ų60.673%0.72530%0.304SS*.Hα-helixtrans-67-21.3178.2-69.9-73.7000113.7V124 P130V124-Y126 PolarHBondContact O-N 3.09Å; Y126-P130 WeakPolarHBondContact O-CD 3.4Å
127R59.2Low77.5Confident205 Ų20562.8 Ų62.877%0.77432%0.315SS*.Hα-helixtrans-89.2-30.1177.3-64.5-174.4179-171-0.6112.6V124 V125V124-R127 HydrophobicContact CG1-CB 3.93Å; V124-R127 CarbonylContact O-C 3.57Å; V124-R127 WeakPolarHBondContact O-CA 3.48Å; V124-R127 WeakPolarHBondContact O-CB 3.35Å; V124-R127 PolarHBondContact O-N 3.32Å; V125-R127 PolarHBondContact O-N 3.01Å
128A69.3Low77.5Confident10 Ų1060 Ų608%0.08331%0.305CS..Hα-helixtrans-81.1-34.6-177.600000112.4V114 V124 V125 T131 A132V114-A128 HydrophobicContact CG1-CB 3.82Å; V114-A128 WeakPolarHBondContact CG1-O 3.18Å; V124-A128 PolarHBondContact O-N 3.09Å; V125-A128 PolarHBondContact O-N 3.42Å; A128-T131 PolarHBondContact O-N 2.97Å; A128-A132 PolarHBondContact O-N 2.74Å
129Y78.3Confident77.9Confident23 Ų2359.1 Ų59.19%0.0930%0.298CS..Hα-helixtrans-51.3-53.6-178175.7-79.9000113.3V125 T131 A132 E133 L156 C157 V160 R162V125-Y129 PolarHBondContact O-N 2.89Å; V125-Y129 VanDerWaalsContact O-N 3.16Å; Y129-T131 PolarHBondContact O-N 3.1Å; Y129-T131 VanDerWaalsContact O-N 3.14Å; Y129-A132 PolarHBondContact O-N 2.89Å; Y129-E133 HydrophobicContact CE1-CB 4.26Å; Y129-E133 VanDerWaalsContact CE1-CD 3.49Å; Y129-E133 HydrophobicContact CE1-CG 4.45Å; Y129-E133 WeakPolarHBondContact CE1-OE2 3.02Å; Y129-E133 VanDerWaalsContact O-CB 3.32Å; Y129-E133 WeakPolarHBondContact O-CB 3.31Å; Y129-E133 PolarHBondContact O-N 3.21Å; Y129-E133 PolarHBondContact OH-OE1 3.17Å; Y129-L156 HydrophobicContact CD2-CD1 3.84Å; Y129-L156 HydrophobicContact CD2-CD2 3.78Å; Y129-L156 HydrophobicContact CD2-CG 3.46Å; Y129-L156 VanDerWaalsContact CD2-CG 3.46Å; Y129-L156 HydrophobicContact CE2-CB 4.37Å; Y129-L156 HydrophobicContact CE2-CD1 4.33Å; Y129-L156 HydrophobicContact CE2-CD2 3.73Å; Y129-L156 HydrophobicContact CE2-CG 3.45Å; Y129-L156 VanDerWaalsContact CE2-CG 3.45Å; Y129-L156 HydrophobicContact CG-CD2 4.34Å; Y129-L156 HydrophobicContact CG-CG 4.4Å; Y129-C157 PolarHBondContact OH-SG 2.95Å; Y129-V160 HydrophobicContact CD2-CB 4.22Å; Y129-V160 HydrophobicContact CD2-CG1 3.5Å; Y129-V160 VanDerWaalsContact CD2-CG1 3.5Å; Y129-V160 HydrophobicContact CD2-CG2 3.7Å; Y129-V160 HydrophobicContact CE2-CB 4.42Å; Y129-V160 HydrophobicContact CE2-CG1 4.14Å; Y129-V160 HydrophobicContact CE2-CG2 3.43Å; Y129-V160 VanDerWaalsContact CE2-CG2 3.43Å; Y129-V160 HydrophobicContact CG-CG1 4.24Å; Y129-R162 PolarHBondContact OH-NH1 3.33Å
130P82.6Confident78Confident68 Ų6857.2 Ų57.244%0.44228%0.282SS..Hα-helixtrans-63.2-26.5-178.4-22.834.7000113.3Y126 K134Y126-P130 WeakPolarHBondContact O-CD 3.4Å; P130-K134 WeakPolarHBondContact O-CB 3.23Å; P130-K134 PolarHBondContact O-N 3.39Å
131T87.1Confident77.8Confident71 Ų7157.3 Ų57.344%0.43628%0.283SS..Hα-helixtrans-78.6-44.2179.6-57.10000110.9V114 A128 Y129 K134 L135V114-T131 HydrophobicContact CG1-CG2 4.41Å; V114-T131 HydrophobicContact CG2-CG2 4.05Å; A128-T131 PolarHBondContact O-N 2.97Å; Y129-T131 PolarHBondContact O-N 3.1Å; Y129-T131 VanDerWaalsContact O-N 3.14Å; T131-K134 PolarHBondContact O-N 2.98Å; T131-L135 HydrophobicContact CG2-CD1 4.18Å; T131-L135 WeakPolarHBondContact O-CD1 3.41Å; T131-L135 VanDerWaalsContact O-CG 3.31Å; T131-L135 WeakPolarHBondContact O-CG 3.37Å; T131-L135 PolarHBondContact O-N 2.8Å; T131-L135 VanDerWaalsContact O-N 3.08Å
132A90.8Very high78.1Confident1 Ų154.3 Ų54.31%0.00827%0.272CS..Hα-helixtrans-64.2-46.317500000111.3V114 R115 A128 Y129 K134 L135 Y136 L156V114-A132 HydrophobicContact CB-CB 4.14Å; V114-A132 HydrophobicContact CG1-CB 3.85Å; R115-A132 HydrophobicContact CG-CB 4.27Å; A128-A132 PolarHBondContact O-N 2.74Å; Y129-A132 PolarHBondContact O-N 2.89Å; A132-K134 VanDerWaalsContact C-N 3.29Å; A132-K134 PolarHBondContact O-N 3.37Å; A132-L135 PolarHBondContact O-N 3.13Å; A132-L135 VanDerWaalsContact O-N 3.15Å; A132-Y136 HydrophobicContact CB-CE2 4.12Å; A132-Y136 WeakPolarHBondContact O-CD2 3.46Å; A132-Y136 PolarHBondContact O-N 3.18Å; A132-L156 HydrophobicContact CB-CD1 4.17Å; A132-L156 HydrophobicContact CB-CD2 3.94Å
133E88Confident78.9Confident36 Ų3651.6 Ų51.617%0.16825%0.252CS..Hα-helixtrans-54.2-47.8176.4-177.1173.9-130.100110.9Y129 L135 Y136 Q137 L153 L156 R162Y129-E133 HydrophobicContact CE1-CB 4.26Å; Y129-E133 VanDerWaalsContact CE1-CD 3.49Å; Y129-E133 HydrophobicContact CE1-CG 4.45Å; Y129-E133 WeakPolarHBondContact CE1-OE2 3.02Å; Y129-E133 VanDerWaalsContact O-CB 3.32Å; Y129-E133 WeakPolarHBondContact O-CB 3.31Å; Y129-E133 PolarHBondContact O-N 3.21Å; Y129-E133 PolarHBondContact OH-OE1 3.17Å; E133-L135 PolarHBondContact O-N 3.03Å; E133-Y136 PolarHBondContact O-N 2.72Å; E133-Q137 WeakPolarHBondContact O-CB 3.49Å; E133-Q137 VanDerWaalsContact O-CG 3.29Å; E133-Q137 WeakPolarHBondContact O-CG 2.98Å; E133-Q137 PolarHBondContact O-N 3.11Å; E133-L153 HydrophobicContact CB-CD2 4.38Å; E133-L153 HydrophobicContact CG-CD2 3.88Å; E133-L156 HydrophobicContact CB-CD2 3.79Å; E133-R162 IonicContact OE1-NH1 2.66Å
134K86.6Confident79.8Confident95 Ų9546.7 Ų46.741%0.41322%0.222SC..Hα-helixtrans-61-42.7177.6-177.2171.9175.8178.40113P130 T131 A132 Q137 Y138P130-K134 WeakPolarHBondContact O-CB 3.23Å; P130-K134 PolarHBondContact O-N 3.39Å; T131-K134 PolarHBondContact O-N 2.98Å; A132-K134 VanDerWaalsContact C-N 3.29Å; A132-K134 PolarHBondContact O-N 3.37Å; K134-Q137 PolarHBondContact O-N 3.35Å; K134-Y138 HydrophobicContact CD-CE1 4.22Å; K134-Y138 WeakPolarHBondContact CE-OH 3.27Å; K134-Y138 HydrophobicContact CG-CD1 4.07Å; K134-Y138 HydrophobicContact CG-CE1 3.45Å; K134-Y138 VanDerWaalsContact CG-CE1 3.45Å; K134-Y138 PolarHBondContact NZ-OH 2.91Å; K134-Y138 WeakPolarHBondContact O-CD1 3.46Å; K134-Y138 VanDerWaalsContact O-CG 3.31Å; K134-Y138 PolarHBondContact O-N 3.39Å
135L91.4Very high81.1Confident18 Ų1846.7 Ų46.79%0.09422%0.22CC..Hα-helixtrans-66.1-40.4179-71.4162.3000112Y107 M110 V114 T131 A132 E133 Y138 A139Y107-L135 HydrophobicContact CD1-CD2 3.84Å; Y107-L135 HydrophobicContact CE1-CD2 4.28Å; M110-L135 HydrophobicContact CB-CD1 3.92Å; M110-L135 HydrophobicContact CB-CD2 4.03Å; M110-L135 HydrophobicContact CB-CG 4.5Å; M110-L135 HydrophobicContact CE-CD2 4.41Å; M110-L135 HydrophobicContact SD-CD2 4.44Å; V114-L135 HydrophobicContact CG2-CD1 3.91Å; T131-L135 HydrophobicContact CG2-CD1 4.18Å; T131-L135 WeakPolarHBondContact O-CD1 3.41Å; T131-L135 VanDerWaalsContact O-CG 3.31Å; T131-L135 WeakPolarHBondContact O-CG 3.37Å; T131-L135 PolarHBondContact O-N 2.8Å; T131-L135 VanDerWaalsContact O-N 3.08Å; A132-L135 PolarHBondContact O-N 3.13Å; A132-L135 VanDerWaalsContact O-N 3.15Å; E133-L135 PolarHBondContact O-N 3.03Å; L135-Y138 WeakPolarHBondContact O-CB 3.36Å; L135-Y138 PolarHBondContact O-N 3.38Å; L135-A139 PolarHBondContact O-N 3.42Å
136Y92.7Very high82.9Confident0 Ų044.9 Ų44.90%021%0.209CC..Hα-helixtrans-68.9-36.2174.4-60.2-47.7000112.4I108 G111 D112 R115 A132 E133 Y138 A139 L140 R152 L153I108-Y136 HydrophobicContact CD1-CD1 3.99Å; I108-Y136 WeakPolarHBondContact O-CE1 3.34Å; G111-Y136 PolarHBondContact O-OH 2.98Å; D112-Y136 WeakPolarHBondContact CA-OH 3.35Å; D112-Y136 PolarHBondContact N-OH 2.7Å; D112-Y136 VanDerWaalsContact N-OH 3.13Å; D112-Y136 PolarHBondContact OD1-OH 2.93Å; R115-Y136 WeakPolarHBondContact CD-OH 3.21Å; A132-Y136 HydrophobicContact CB-CE2 4.12Å; A132-Y136 WeakPolarHBondContact O-CD2 3.46Å; A132-Y136 PolarHBondContact O-N 3.18Å; E133-Y136 PolarHBondContact O-N 2.72Å; Y136-Y138 VanDerWaalsContact C-N 3.26Å; Y136-Y138 PolarHBondContact O-N 3.44Å; Y136-A139 PolarHBondContact O-N 2.94Å; Y136-L140 VanDerWaalsContact O-CB 3.3Å; Y136-L140 WeakPolarHBondContact O-CB 3.48Å; Y136-L140 PolarHBondContact O-N 2.98Å; Y136-R152 HydrophobicContact CD1-CB 3.7Å; Y136-R152 HydrophobicContact CD1-CG 4.17Å; Y136-R152 HydrophobicContact CD2-CB 3.9Å; Y136-R152 HydrophobicContact CE1-CB 3.6Å; Y136-R152 HydrophobicContact CE1-CG 3.84Å; Y136-R152 HydrophobicContact CE2-CB 3.82Å; Y136-R152 HydrophobicContact CG-CB 3.85Å; Y136-L153 HydrophobicContact CD2-CD2 4.3Å; Y136-L153 HydrophobicContact CD2-CG 4.49Å
137Q87.2Confident84.7Confident62 Ų6236.1 Ų36.129%0.2918%0.175SC..Hα-helixtrans-62.7-33.6171.2-74.3173.6-6.400112.1L85 E133 K134 L140 S141 L153L85-Q137 WeakPolarHBondContact CD2-O 3.11Å; E133-Q137 WeakPolarHBondContact O-CB 3.49Å; E133-Q137 VanDerWaalsContact O-CG 3.29Å; E133-Q137 WeakPolarHBondContact O-CG 2.98Å; E133-Q137 PolarHBondContact O-N 3.11Å; K134-Q137 PolarHBondContact O-N 3.35Å; Q137-L140 PolarHBondContact O-N 3.49Å; Q137-S141 WeakPolarHBondContact O-CB 3.33Å; Q137-S141 PolarHBondContact O-N 3.15Å; Q137-L153 HydrophobicContact CG-CD1 4.47Å; Q137-L153 HydrophobicContact CG-CD2 4.44Å
138Y87.4Confident86.4Confident27 Ų2727.7 Ų27.711%0.10615%0.146CC..Hα-helixtrans-65.9-48.2173.8-70.611.7000111V81 P82 Y107 K134 L135 Y136 L140 S141 L142V81-Y138 HydrophobicContact CG1-CE1 4.2Å; V81-Y138 WeakPolarHBondContact CG1-OH 3.49Å; V81-Y138 VanDerWaalsContact CG2-OH 3.29Å; V81-Y138 WeakPolarHBondContact CG2-OH 3.47Å; P82-Y138 HydrophobicContact CG-CD1 3.53Å; P82-Y138 HydrophobicContact CG-CE1 3.95Å; P82-Y138 HydrophobicContact CG-CG 4.15Å; Y107-Y138 HydrophobicContact CD1-CD2 4.18Å; Y107-Y138 AromaticContact CE1-CD2 3.72Å; Y107-Y138 HydrophobicContact CE1-CD2 3.72Å; Y107-Y138 HydrophobicContact CE2-CD2 4.22Å; Y107-Y138 AromaticContact CZ-CD2 3.74Å; K134-Y138 HydrophobicContact CD-CE1 4.22Å; K134-Y138 WeakPolarHBondContact CE-OH 3.27Å; K134-Y138 HydrophobicContact CG-CD1 4.07Å; K134-Y138 HydrophobicContact CG-CE1 3.45Å; K134-Y138 VanDerWaalsContact CG-CE1 3.45Å; K134-Y138 PolarHBondContact NZ-OH 2.91Å; K134-Y138 WeakPolarHBondContact O-CD1 3.46Å; K134-Y138 VanDerWaalsContact O-CG 3.31Å; K134-Y138 PolarHBondContact O-N 3.39Å; L135-Y138 WeakPolarHBondContact O-CB 3.36Å; L135-Y138 PolarHBondContact O-N 3.38Å; Y136-Y138 VanDerWaalsContact C-N 3.26Å; Y136-Y138 PolarHBondContact O-N 3.44Å; Y138-L140 VanDerWaalsContact C-N 3.3Å; Y138-L140 PolarHBondContact O-N 3.15Å; Y138-S141 WeakPolarHBondContact O-CB 3.36Å; Y138-S141 PolarHBondContact O-N 3.25Å; Y138-S141 VanDerWaalsContact O-N 3.14Å; Y138-S141 PolarHBondContact O-OG 2.84Å; Y138-L142 PolarHBondContact O-N 2.92Å
139A91.3Very high87.5Confident0 Ų027.2 Ų27.20%014%0.142CC..Hα-helixtrans-56.7-46.9174.400000111.2Y104 I108 L135 Y136 S141 L142 K143 P149Y104-A139 HydrophobicContact CD2-CB 3.84Å; Y104-A139 WeakPolarHBondContact CD2-O 3.25Å; Y104-A139 HydrophobicContact CE2-CB 4.08Å; I108-A139 HydrophobicContact CD1-CB 3.51Å; I108-A139 HydrophobicContact CG1-CB 3.9Å; L135-A139 PolarHBondContact O-N 3.42Å; Y136-A139 PolarHBondContact O-N 2.94Å; A139-S141 VanDerWaalsContact C-N 3.27Å; A139-S141 PolarHBondContact O-N 3.35Å; A139-L142 PolarHBondContact O-N 2.97Å; A139-K143 PolarHBondContact O-N 3.5Å; A139-P149 HydrophobicContact CB-CG 4.31Å
140L87.7Confident88.2Confident3 Ų326.2 Ų26.22%0.01614%0.138CC..Hα-helixtrans-60.8-35178.1-17256.7000112.9L85 W87 Y136 Q137 Y138 L142 K143 P144 P149 F150 L153L85-L140 HydrophobicContact CD2-CB 4.07Å; L85-L140 HydrophobicContact CD2-CD2 4.25Å; L85-L140 HydrophobicContact CD2-CG 4.03Å; W87-L140 HydrophobicContact CH2-CD1 3.56Å; W87-L140 HydrophobicContact CH2-CD2 3.52Å; W87-L140 HydrophobicContact CH2-CG 3.29Å; W87-L140 HydrophobicContact CZ2-CD2 3.97Å; W87-L140 HydrophobicContact CZ2-CG 3.95Å; W87-L140 HydrophobicContact CZ3-CD1 3.9Å; W87-L140 HydrophobicContact CZ3-CG 4.03Å; Y136-L140 VanDerWaalsContact O-CB 3.3Å; Y136-L140 WeakPolarHBondContact O-CB 3.48Å; Y136-L140 PolarHBondContact O-N 2.98Å; Q137-L140 PolarHBondContact O-N 3.49Å; Y138-L140 VanDerWaalsContact C-N 3.3Å; Y138-L140 PolarHBondContact O-N 3.15Å; L140-L142 PolarHBondContact O-N 3.46Å; L140-K143 CarbonylContact O-C 3.55Å; L140-P144 WeakPolarHBondContact O-CA 3.45Å; L140-P149 HydrophobicContact CB-CB 3.75Å; L140-P149 HydrophobicContact CB-CG 4.16Å; L140-P149 HydrophobicContact CD1-CB 4.05Å; L140-P149 HydrophobicContact CD1-CG 4.11Å; L140-P149 HydrophobicContact CG-CB 4.36Å; L140-F150 HydrophobicContact CD1-CD2 3.94Å; L140-F150 HydrophobicContact CD1-CE1 4.09Å; L140-F150 HydrophobicContact CD1-CE2 3.45Å; L140-F150 VanDerWaalsContact CD1-CE2 3.45Å; L140-F150 HydrophobicContact CD1-CG 4.48Å; L140-F150 HydrophobicContact CD1-CZ 3.55Å; L140-F150 HydrophobicContact CD2-CD1 4.26Å; L140-F150 HydrophobicContact CD2-CE1 3.85Å; L140-F150 HydrophobicContact CD2-CZ 4.11Å; L140-F150 HydrophobicContact CG-CZ 4.38Å; L140-L153 HydrophobicContact CD2-CD1 4.07Å
141S81.4Confident88.7Confident8 Ų823 Ų236%0.05612%0.117CC..Hα-helixtrans-67.8-23.717679.40000113.8P82 R86 Q137 Y138 A139P82-S141 VanDerWaalsContact CG-OG 3.28Å; P82-S141 WeakPolarHBondContact CG-OG 3.31Å; R86-S141 VanDerWaalsContact O-O 3.09Å; Q137-S141 WeakPolarHBondContact O-CB 3.33Å; Q137-S141 PolarHBondContact O-N 3.15Å; Y138-S141 WeakPolarHBondContact O-CB 3.36Å; Y138-S141 PolarHBondContact O-N 3.25Å; Y138-S141 VanDerWaalsContact O-N 3.14Å; Y138-S141 PolarHBondContact O-OG 2.84Å; A139-S141 VanDerWaalsContact C-N 3.27Å; A139-S141 PolarHBondContact O-N 3.35Å
142L85.1Confident89Confident17 Ų1722 Ų229%0.08911%0.106CC..Hα-helixtrans-87.9-42.2178.8-64.9-179.6000111.3T77 V78 V100 I103 Y107 Y138 A139 L140T77-L142 HydrophobicContact CG2-CD2 4.25Å; V78-L142 HydrophobicContact CG1-CD1 4.45Å; V78-L142 HydrophobicContact CG1-CD2 4.13Å; V100-L142 HydrophobicContact CG1-CB 4.1Å; I103-L142 HydrophobicContact CB-CD1 4.43Å; I103-L142 HydrophobicContact CG2-CD1 4Å; Y107-L142 HydrophobicContact CD2-CD1 3.87Å; Y107-L142 HydrophobicContact CE2-CD1 4Å; Y138-L142 PolarHBondContact O-N 2.92Å; A139-L142 PolarHBondContact O-N 2.97Å; L140-L142 PolarHBondContact O-N 3.46Å
143K86Confident89.1Confident33 Ų3322 Ų2214%0.14311%0.105CC..  trans-127.484178.4-62.8-164.975.2-176.40110.7E101 Y104 A139 L140 D145 E146 E178E101-K143 IonicContact OE1-NZ 3.67Å; E101-K143 PolarHBondContact OE1-NZ 2.89Å; E101-K143 VanDerWaalsContact OE1-NZ 3.17Å; E101-K143 VanDerWaalsContact OE2-CD 3.24Å; E101-K143 WeakPolarHBondContact OE2-CD 3.35Å; E101-K143 WeakPolarHBondContact OE2-CE 3.38Å; E101-K143 IonicContact OE2-NZ 3.79Å; E101-K143 PolarHBondContact OE2-NZ 2.78Å; Y104-K143 HydrophobicContact CD1-CD 3.72Å; Y104-K143 HydrophobicContact CD1-CG 4.42Å; Y104-K143 HydrophobicContact CD2-CB 3.73Å; Y104-K143 HydrophobicContact CD2-CD 4.01Å; Y104-K143 HydrophobicContact CD2-CG 3.84Å; Y104-K143 HydrophobicContact CE1-CD 4.1Å; Y104-K143 HydrophobicContact CE2-CB 3.81Å; Y104-K143 HydrophobicContact CE2-CD 4.34Å; Y104-K143 HydrophobicContact CE2-CG 4.33Å; Y104-K143 HydrophobicContact CG-CB 4.28Å; Y104-K143 HydrophobicContact CG-CD 3.69Å; Y104-K143 HydrophobicContact CG-CG 3.89Å; A139-K143 PolarHBondContact O-N 3.5Å; L140-K143 CarbonylContact O-C 3.55Å; K143-D145 VanDerWaalsContact C-N 3.29Å; K143-D145 PolarHBondContact O-N 3.04Å; K143-E146 HydrophobicContact CB-CB 4.17Å; K143-E146 HydrophobicContact CB-CG 3.78Å; K143-E146 HydrophobicContact CD-CG 4.04Å; K143-E146 IonicContact NZ-OE1 2.68Å; K143-E146 PolarHBondContact NZ-OE1 2.8Å; K143-E146 PolarHBondContact O-N 2.87Å; K143-E178 IonicContact NZ-OE2 3.57Å
144P81.4Confident89.4Confident25 Ų2520.2 Ų20.216%0.16210%0.097CC..THydrogen-bonded Turntrans-67.1-27.4-177.524.6-35.8000114.9W87 L140 E146W87-P144 HydrophobicContact CD2-CB 4.01Å; W87-P144 HydrophobicContact CE3-CB 2.99Å; W87-P144 HydrophobicContact CE3-CG 4.27Å; W87-P144 HydrophobicContact CZ3-CB 3.29Å; L140-P144 WeakPolarHBondContact O-CA 3.45Å; P144-E146 VanDerWaalsContact C-N 3.3Å
145D84.3Confident89.6Confident56 Ų5617.1 Ų17.130%0.2998%0.084SC..THydrogen-bonded Turntrans-83.8-4.2-176.3-75.7-34.9000113.1K143 A176 K177 E178K143-D145 VanDerWaalsContact C-N 3.29Å; K143-D145 PolarHBondContact O-N 3.04Å; D145-A176 WeakPolarHBondContact O-CB 3.24Å; D145-K177 HydrophobicContact CB-CB 4.25Å; D145-K177 HydrophobicContact CB-CD 4.41Å; D145-K177 HydrophobicContact CB-CG 4.46Å; D145-K177 PolarHBondContact O-N 3.38Å; D145-K177 WeakPolarHBondContact OD1-CE 3.44Å; D145-K177 IonicContact OD1-NZ 2.78Å; D145-K177 PolarHBondContact OD1-NZ 3.39Å; D145-K177 IonicContact OD2-NZ 3.9Å; D145-K177 PolarHBondContact OD2-NZ 2.93Å; D145-E178 PolarHBondContact O-N 3.27Å
146E89.5Confident89.6Confident0 Ų016.7 Ų16.70%08%0.082CC..BIsolated β-bridgetrans-90133.2-179.1-76.5-87.3-155.400111.8Y104 K143 P144 P149 F150 E178 R179Y104-E146 HydrophobicContact CE2-CB 4.29Å; Y104-E146 WeakPolarHBondContact OH-CB 3.26Å; K143-E146 HydrophobicContact CB-CB 4.17Å; K143-E146 HydrophobicContact CB-CG 3.78Å; K143-E146 HydrophobicContact CD-CG 4.04Å; K143-E146 IonicContact NZ-OE1 2.68Å; K143-E146 PolarHBondContact NZ-OE1 2.8Å; K143-E146 PolarHBondContact O-N 2.87Å; P144-E146 VanDerWaalsContact C-N 3.3Å; E146-P149 VanDerWaalsContact O-CD 3.3Å; E146-P149 WeakPolarHBondContact O-CD 3.34Å; E146-F150 WeakPolarHBondContact O-CD2 3.13Å; E146-E178 HydrophobicContact CG-CB 4.43Å; E146-R179 IonicContact OE1-CZ 3.16Å; E146-R179 IonicContact OE1-NH1 2.91Å; E146-R179 PolarHBondContact OE1-NH1 2.76Å; E146-R179 IonicContact OE2-CZ 2.8Å; E146-R179 IonicContact OE2-NH1 2.65Å; E146-R179 PolarHBondContact OE2-NH1 2.56Å
147S92.2Very high89.4Confident0 Ų016.7 Ų16.70%08%0.082CC..SBendtrans-71.6-29.7179.8-166.80000113.9F150 S151 G173 E178 R179 S183S147-F150 VanDerWaalsContact O-CB 3.3Å; S147-F150 WeakPolarHBondContact O-CB 3.45Å; S147-F150 PolarHBondContact O-N 3.27Å; S147-S151 PolarHBondContact O-N 3.3Å; S147-S151 PolarHBondContact O-OG 2.91Å; S147-G173 WeakPolarHBondContact CB-O 3.12Å; S147-G173 PolarHBondContact OG-O 3.28Å; S147-E178 WeakPolarHBondContact CB-O 3.38Å; S147-E178 PolarHBondContact N-O 2.9Å; S147-E178 VanDerWaalsContact N-O 3.09Å; S147-R179 WeakPolarHBondContact CB-O 3.2Å; S147-R179 PolarHBondContact OG-O 3.44Å; S147-S183 VanDerWaalsContact OG-CB 3.24Å; S147-S183 WeakPolarHBondContact OG-CB 3.46Å; S147-S183 PolarHBondContact OG-OG 2.73Å; S147-S183 VanDerWaalsContact OG-OG 3.06Å
148T93.6Very high89.5Confident28 Ų2816.4 Ų16.417%0.1729%0.087CC..Hα-helixtrans-53.9-48.7-170.2-48.70000114.5Y104 I108 F150 S151 R152Y104-T148 WeakPolarHBondContact OH-CB 3.28Å; I108-T148 HydrophobicContact CD1-CG2 4.42Å; I108-T148 HydrophobicContact CG2-CG2 4.36Å; T148-F150 VanDerWaalsContact C-N 3.27Å; T148-F150 PolarHBondContact O-N 3.14Å; T148-S151 WeakPolarHBondContact O-CB 3.31Å; T148-S151 PolarHBondContact O-N 3.12Å; T148-R152 HydrophobicContact CG2-CG 4.4Å; T148-R152 VanDerWaalsContact O-CG 3.24Å; T148-R152 WeakPolarHBondContact O-CG 3.31Å; T148-R152 PolarHBondContact O-N 3.32Å
149P92.9Very high89.3Confident0 Ų019 Ų190%011%0.109CC..Hα-helixtrans-61.3-36.2179-15.227.5000112.4Y104 I108 A139 L140 E146 R152 L153Y104-P149 HydrophobicContact CE2-CG 3.76Å; I108-P149 HydrophobicContact CD1-CB 4.15Å; I108-P149 HydrophobicContact CD1-CG 4.02Å; A139-P149 HydrophobicContact CB-CG 4.31Å; L140-P149 HydrophobicContact CB-CB 3.75Å; L140-P149 HydrophobicContact CB-CG 4.16Å; L140-P149 HydrophobicContact CD1-CB 4.05Å; L140-P149 HydrophobicContact CD1-CG 4.11Å; L140-P149 HydrophobicContact CG-CB 4.36Å; E146-P149 VanDerWaalsContact O-CD 3.3Å; E146-P149 WeakPolarHBondContact O-CD 3.34Å; P149-R152 PolarHBondContact O-N 2.85Å; P149-L153 WeakPolarHBondContact O-CB 3.45Å; P149-L153 VanDerWaalsContact O-CG 3.28Å; P149-L153 WeakPolarHBondContact O-CG 3.35Å; P149-L153 PolarHBondContact O-N 3.35Å
150F93Very high88.8Confident3 Ų321 Ų211%0.01312%0.121CC..Hα-helixtrans-63.8-47175.3-66.6-72.9000111.5W87 L140 E146 S147 T148 R152 L153 G154 Y169 R172W87-F150 HydrophobicContact CH2-CE1 4.37Å; W87-F150 AromaticContact CH2-CZ 3.86Å; W87-F150 HydrophobicContact CH2-CZ 3.86Å; W87-F150 HydrophobicContact CZ3-CZ 4.15Å; L140-F150 HydrophobicContact CD1-CD2 3.94Å; L140-F150 HydrophobicContact CD1-CE1 4.09Å; L140-F150 HydrophobicContact CD1-CE2 3.45Å; L140-F150 VanDerWaalsContact CD1-CE2 3.45Å; L140-F150 HydrophobicContact CD1-CG 4.48Å; L140-F150 HydrophobicContact CD1-CZ 3.55Å; L140-F150 HydrophobicContact CD2-CD1 4.26Å; L140-F150 HydrophobicContact CD2-CE1 3.85Å; L140-F150 HydrophobicContact CD2-CZ 4.11Å; L140-F150 HydrophobicContact CG-CZ 4.38Å; E146-F150 WeakPolarHBondContact O-CD2 3.13Å; S147-F150 VanDerWaalsContact O-CB 3.3Å; S147-F150 WeakPolarHBondContact O-CB 3.45Å; S147-F150 PolarHBondContact O-N 3.27Å; T148-F150 VanDerWaalsContact C-N 3.27Å; T148-F150 PolarHBondContact O-N 3.14Å; F150-R152 VanDerWaalsContact C-N 3.25Å; F150-R152 PolarHBondContact O-N 3.37Å; F150-L153 PolarHBondContact O-N 2.89Å; F150-G154 PolarHBondContact O-N 2.9Å; F150-Y169 WeakPolarHBondContact CB-O 3.34Å; F150-Y169 HydrophobicContact CD1-CD1 4.14Å; F150-R172 HydrophobicContact CD1-CB 3.85Å; F150-R172 HydrophobicContact CE1-CB 3.74Å; F150-R172 HydrophobicContact CZ-CB 4.3Å
151S93.6Very high88.5Confident0 Ų023.4 Ų23.40%015%0.147CC..Hα-helixtrans-54.5-44.1174.1-57.90000111.2S147 T148 G154 M155 H170 E182 S183S147-S151 PolarHBondContact O-N 3.3Å; S147-S151 PolarHBondContact O-OG 2.91Å; T148-S151 WeakPolarHBondContact O-CB 3.31Å; T148-S151 PolarHBondContact O-N 3.12Å; S151-G154 PolarHBondContact O-N 3.25Å; S151-M155 WeakPolarHBondContact O-CG 3.21Å; S151-M155 PolarHBondContact O-N 3.44Å; S151-H170 PolarHBondContact O-CE1 3.41Å; S151-E182 PolarHBondContact OG-OE2 2.65Å; S151-S183 PolarHBondContact N-OG 3.28Å; S151-S183 PolarHBondContact OG-N 3.02Å; S151-S183 PolarHBondContact OG-OG 2.79Å
152R93.9Very high88.8Confident50 Ų5026 Ų2619%0.18916%0.156CC..Hα-helixtrans-68.5-43.5-178.9-61.7-71.2153.5166-6.2112.6D112 Y136 T148 P149 F150 M155 L156 E182D112-R152 VanDerWaalsContact CG-NH1 3.35Å; D112-R152 WeakPolarHBondContact OD1-CD 3.09Å; D112-R152 IonicContact OD1-CZ 3.15Å; D112-R152 IonicContact OD1-NH1 2.78Å; D112-R152 PolarHBondContact OD1-NH1 3.17Å; D112-R152 IonicContact OD2-CZ 2.68Å; D112-R152 IonicContact OD2-NH1 3.58Å; D112-R152 PolarHBondContact OD2-NH1 3.34Å; Y136-R152 HydrophobicContact CD1-CB 3.7Å; Y136-R152 HydrophobicContact CD1-CG 4.17Å; Y136-R152 HydrophobicContact CD2-CB 3.9Å; Y136-R152 HydrophobicContact CE1-CB 3.6Å; Y136-R152 HydrophobicContact CE1-CG 3.84Å; Y136-R152 HydrophobicContact CE2-CB 3.82Å; Y136-R152 HydrophobicContact CG-CB 3.85Å; T148-R152 HydrophobicContact CG2-CG 4.4Å; T148-R152 VanDerWaalsContact O-CG 3.24Å; T148-R152 WeakPolarHBondContact O-CG 3.31Å; T148-R152 PolarHBondContact O-N 3.32Å; P149-R152 PolarHBondContact O-N 2.85Å; F150-R152 VanDerWaalsContact C-N 3.25Å; F150-R152 PolarHBondContact O-N 3.37Å; R152-M155 HydrophobicContact CG-CE 4.45Å; R152-L156 WeakPolarHBondContact O-CB 3.49Å; R152-L156 PolarHBondContact O-N 3.23Å; R152-E182 IonicContact NH2-OE1 3.72Å
153L93.2Very high89Confident0 Ų026.8 Ų26.80%016%0.162CC..Hα-helixtrans-62.9-43.7174.4-74165.6000111.3E133 Y136 Q137 L140 P149 F150 L156 C157 Y169E133-L153 HydrophobicContact CB-CD2 4.38Å; E133-L153 HydrophobicContact CG-CD2 3.88Å; Y136-L153 HydrophobicContact CD2-CD2 4.3Å; Y136-L153 HydrophobicContact CD2-CG 4.49Å; Q137-L153 HydrophobicContact CG-CD1 4.47Å; Q137-L153 HydrophobicContact CG-CD2 4.44Å; L140-L153 HydrophobicContact CD2-CD1 4.07Å; P149-L153 WeakPolarHBondContact O-CB 3.45Å; P149-L153 VanDerWaalsContact O-CG 3.28Å; P149-L153 WeakPolarHBondContact O-CG 3.35Å; P149-L153 PolarHBondContact O-N 3.35Å; F150-L153 PolarHBondContact O-N 2.89Å; L153-L156 WeakPolarHBondContact O-CB 3.14Å; L153-L156 PolarHBondContact O-N 2.87Å; L153-C157 PolarHBondContact O-N 3.49Å; L153-C157 PolarHBondContact O-SG 2.81Å; L153-C157 VanDerWaalsContact O-SG 3.35Å; L153-Y169 HydrophobicContact CB-CD1 3.89Å; L153-Y169 HydrophobicContact CB-CD2 3.69Å; L153-Y169 HydrophobicContact CB-CE1 4.06Å; L153-Y169 HydrophobicContact CB-CE2 3.85Å; L153-Y169 HydrophobicContact CB-CG 3.7Å; L153-Y169 HydrophobicContact CD1-CD1 4.04Å; L153-Y169 HydrophobicContact CD1-CE1 3.7Å; L153-Y169 HydrophobicContact CG-CE1 4.39Å
154G93.2Very high89.2Confident0 Ų025.3 Ų25.30%016%0.156CC..Hα-helixtrans-63.4-43.517800000113.3F150 S151 L156 C157 S158 A166 H170F150-G154 PolarHBondContact O-N 2.9Å; S151-G154 PolarHBondContact O-N 3.25Å; G154-L156 VanDerWaalsContact C-N 3.32Å; G154-L156 PolarHBondContact O-N 3.06Å; G154-C157 PolarHBondContact O-N 2.83Å; G154-S158 WeakPolarHBondContact O-CB 3.21Å; G154-S158 PolarHBondContact O-N 3.4Å; G154-S158 PolarHBondContact O-OG 3.19Å; G154-A166 VanDerWaalsContact O-CB 3.24Å; G154-A166 WeakPolarHBondContact O-CB 3.42Å; G154-H170 WeakPolarHBondContact CA-NE2 3.45Å
155M91.7Very high89.6Confident29 Ų2924.5 Ų24.514%0.14315%0.15CC..Hα-helixtrans-61.4-41.2172.4-77.5-171.3-76.700112.1S151 R152 S158 S159 Y186S151-M155 WeakPolarHBondContact O-CG 3.21Å; S151-M155 PolarHBondContact O-N 3.44Å; R152-M155 HydrophobicContact CG-CE 4.45Å; M155-S158 PolarHBondContact O-N 3.39Å; M155-S159 PolarHBondContact O-N 2.92Å; M155-Y186 HydrophobicContact CE-CE2 4.34Å; M155-Y186 HydrophobicContact CG-CE1 4.31Å; M155-Y186 HydrophobicContact CG-CE2 4.48Å; M155-Y186 HydrophobicContact SD-CE1 4.2Å; M155-Y186 HydrophobicContact SD-CE2 4.17Å
156L90.6Very high90Very high9 Ų921.9 Ų21.95%0.04714%0.136CC..Hα-helixtrans-63.7-46.8178.9-174.270.2000110.7R115 Y129 A132 E133 R152 L153 G154 S158 S159 V160R115-L156 HydrophobicContact CG-CD1 4.09Å; Y129-L156 HydrophobicContact CD2-CD1 3.84Å; Y129-L156 HydrophobicContact CD2-CD2 3.78Å; Y129-L156 HydrophobicContact CD2-CG 3.46Å; Y129-L156 VanDerWaalsContact CD2-CG 3.46Å; Y129-L156 HydrophobicContact CE2-CB 4.37Å; Y129-L156 HydrophobicContact CE2-CD1 4.33Å; Y129-L156 HydrophobicContact CE2-CD2 3.73Å; Y129-L156 HydrophobicContact CE2-CG 3.45Å; Y129-L156 VanDerWaalsContact CE2-CG 3.45Å; Y129-L156 HydrophobicContact CG-CD2 4.34Å; Y129-L156 HydrophobicContact CG-CG 4.4Å; A132-L156 HydrophobicContact CB-CD1 4.17Å; A132-L156 HydrophobicContact CB-CD2 3.94Å; E133-L156 HydrophobicContact CB-CD2 3.79Å; R152-L156 WeakPolarHBondContact O-CB 3.49Å; R152-L156 PolarHBondContact O-N 3.23Å; L153-L156 WeakPolarHBondContact O-CB 3.14Å; L153-L156 PolarHBondContact O-N 2.87Å; G154-L156 VanDerWaalsContact C-N 3.32Å; G154-L156 PolarHBondContact O-N 3.06Å; L156-S158 PolarHBondContact O-N 2.92Å; L156-S159 PolarHBondContact O-N 3.29Å; L156-S159 PolarHBondContact O-OG 3.47Å; L156-V160 PolarHBondContact O-N 3.44Å
157C89.3Confident90.2Very high0 Ų021.9 Ų21.90%014%0.136CC..Hα-helixtrans-60.5-43.9174.8-67.30000111.9Y129 L153 G154 S159 V160 G161 R162 E165 A166 Y169Y129-C157 PolarHBondContact OH-SG 2.95Å; L153-C157 PolarHBondContact O-N 3.49Å; L153-C157 PolarHBondContact O-SG 2.81Å; L153-C157 VanDerWaalsContact O-SG 3.35Å; G154-C157 PolarHBondContact O-N 2.83Å; C157-S159 VanDerWaalsContact C-N 3.27Å; C157-S159 PolarHBondContact O-N 2.95Å; C157-V160 VanDerWaalsContact O-CG2 3.32Å; C157-V160 WeakPolarHBondContact O-CG2 3.33Å; C157-V160 PolarHBondContact O-N 3.43Å; C157-G161 PolarHBondContact O-N 2.88Å; C157-R162 HydrophobicContact CB-CB 4.02Å; C157-R162 WeakPolarHBondContact O-CB 3.32Å; C157-R162 PolarHBondContact O-N 3.4Å; C157-E165 HydrophobicContact CB-CB 4.33Å; C157-A166 HydrophobicContact CB-CB 3.76Å; C157-Y169 VanDerWaalsContact SG-CE2 3.56Å
158S88.4Confident90.2Very high56 Ų5622.1 Ų22.139%0.39214%0.138SC..Hα-helixtrans-57.8-41.9176.7-61.60000111.7G154 M155 L156 V160 G161 A166G154-S158 WeakPolarHBondContact O-CB 3.21Å; G154-S158 PolarHBondContact O-N 3.4Å; G154-S158 PolarHBondContact O-OG 3.19Å; M155-S158 PolarHBondContact O-N 3.39Å; L156-S158 PolarHBondContact O-N 2.92Å; S158-V160 PolarHBondContact O-N 3.5Å; S158-G161 PolarHBondContact O-N 2.93Å; S158-A166 WeakPolarHBondContact OG-CB 3.24Å
159S83Confident90.2Very high82 Ų8222 Ų2257%0.57313%0.134SC*.Hα-helixtrans-66.8-18.8-178.274.20000114.9M155 L156 C157M155-S159 PolarHBondContact O-N 2.92Å; L156-S159 PolarHBondContact O-N 3.29Å; L156-S159 PolarHBondContact O-OG 3.47Å; C157-S159 VanDerWaalsContact C-N 3.27Å; C157-S159 PolarHBondContact O-N 2.95Å
160V80.2Confident90.3Very high41 Ų4122.1 Ų22.125%0.24814%0.135CC..THydrogen-bonded Turntrans-108.513.6179.3-61.10000113.4V125 Y129 L156 C157 S158 R162V125-V160 HydrophobicContact CG1-CG1 4.27Å; Y129-V160 HydrophobicContact CD2-CB 4.22Å; Y129-V160 HydrophobicContact CD2-CG1 3.5Å; Y129-V160 VanDerWaalsContact CD2-CG1 3.5Å; Y129-V160 HydrophobicContact CD2-CG2 3.7Å; Y129-V160 HydrophobicContact CE2-CB 4.42Å; Y129-V160 HydrophobicContact CE2-CG1 4.14Å; Y129-V160 HydrophobicContact CE2-CG2 3.43Å; Y129-V160 VanDerWaalsContact CE2-CG2 3.43Å; Y129-V160 HydrophobicContact CG-CG1 4.24Å; L156-V160 PolarHBondContact O-N 3.44Å; C157-V160 VanDerWaalsContact O-CG2 3.32Å; C157-V160 WeakPolarHBondContact O-CG2 3.33Å; C157-V160 PolarHBondContact O-N 3.43Å; S158-V160 PolarHBondContact O-N 3.5Å; V160-R162 HydrophobicContact CG2-CB 4.16Å; V160-R162 HydrophobicContact CG2-CG 4.02Å
161G82.6Confident90.3Very high55 Ų5522 Ų2257%0.56713%0.134SC*.THydrogen-bonded Turntrans76.23217800000114C157 S158 P163C157-G161 PolarHBondContact O-N 2.88Å; S158-G161 PolarHBondContact O-N 2.93Å; G161-P163 WeakPolarHBondContact O-CD 3.21Å
162R86.7Confident90.1Very high61 Ų6122.5 Ų22.523%0.2314%0.136CC..  trans-114.165.2-179-79-178.372.8-162.4-1111.9Y129 E133 C157 V160 L164 E165 A166Y129-R162 PolarHBondContact OH-NH1 3.33Å; E133-R162 IonicContact OE1-NH1 2.66Å; C157-R162 HydrophobicContact CB-CB 4.02Å; C157-R162 WeakPolarHBondContact O-CB 3.32Å; C157-R162 PolarHBondContact O-N 3.4Å; V160-R162 HydrophobicContact CG2-CB 4.16Å; V160-R162 HydrophobicContact CG2-CG 4.02Å; R162-L164 PolarHBondContact O-N 2.71Å; R162-E165 HydrophobicContact CB-CB 4.5Å; R162-E165 WeakPolarHBondContact CB-OE2 3.18Å; R162-E165 VanDerWaalsContact CG-OE2 3.25Å; R162-E165 WeakPolarHBondContact CG-OE2 3.35Å; R162-E165 VanDerWaalsContact CZ-CD 3.41Å; R162-E165 IonicContact CZ-OE1 2.74Å; R162-E165 VanDerWaalsContact CZ-OE1 3.31Å; R162-E165 IonicContact CZ-OE2 3.58Å; R162-E165 IonicContact NE-OE1 3.1Å; R162-E165 PolarHBondContact NE-OE1 3.38Å; R162-E165 IonicContact NE-OE2 3.49Å; R162-E165 PolarHBondContact NE-OE2 3.02Å; R162-E165 IonicContact NH2-OE1 2.7Å; R162-E165 PolarHBondContact NH2-OE1 3.4Å; R162-E165 IonicContact NH2-OE2 3.67Å; R162-E165 PolarHBondContact O-N 3.34Å; R162-A166 WeakPolarHBondContact O-CB 3.3Å; R162-A166 PolarHBondContact O-N 2.85Å
163P90.2Very high90Very high35 Ų3520.1 Ų20.123%0.22713%0.127CC..Hα-helixtrans-71.8-30.4-167.530.8-39000114.1G161 A166 A167 I222 L226G161-P163 WeakPolarHBondContact O-CD 3.21Å; P163-A166 PolarHBondContact O-N 3.19Å; P163-A167 VanDerWaalsContact O-CB 3.23Å; P163-A167 WeakPolarHBondContact O-CB 3.44Å; P163-A167 PolarHBondContact O-N 2.83Å; P163-I222 HydrophobicContact CG-CG2 3.53Å; P163-L226 HydrophobicContact CB-CD1 3.93Å; P163-L226 HydrophobicContact CG-CD1 4.49Å
164L89.4Confident89.9Confident2 Ų221 Ų211%0.0113%0.133CC..Hα-helixtrans-67.6-41.6174-82.6172.7000112R162 A166 A167 C168 I222 L226 T279 L283 I286R162-L164 PolarHBondContact O-N 2.71Å; L164-A166 VanDerWaalsContact C-N 3.34Å; L164-A167 PolarHBondContact O-N 3Å; L164-C168 WeakPolarHBondContact O-CB 3.16Å; L164-C168 PolarHBondContact O-N 3.35Å; L164-I222 HydrophobicContact CD1-CB 4.42Å; L164-I222 HydrophobicContact CD1-CG1 3.86Å; L164-I222 HydrophobicContact CD1-CG2 4.31Å; L164-I222 HydrophobicContact CG-CG1 4.44Å; L164-I222 HydrophobicContact CG-CG2 3.99Å; L164-L226 HydrophobicContact CD2-CD2 3.85Å; L164-L226 HydrophobicContact CD2-CG 3.93Å; L164-T279 HydrophobicContact CB-CG2 4.25Å; L164-T279 HydrophobicContact CD1-CG2 3.52Å; L164-L283 HydrophobicContact CD2-CD1 4.17Å; L164-I286 HydrophobicContact CD2-CD1 4.23Å; L164-I286 WeakPolarHBondContact O-CD1 3.27Å
165E90.8Very high89.7Confident8 Ų824.7 Ų24.74%0.03715%0.147CC..Hα-helixtrans-70.3-36.3176.8-66.4127.314700111C157 R162 C168 Y169 S282C157-E165 HydrophobicContact CB-CB 4.33Å; R162-E165 HydrophobicContact CB-CB 4.5Å; R162-E165 WeakPolarHBondContact CB-OE2 3.18Å; R162-E165 VanDerWaalsContact CG-OE2 3.25Å; R162-E165 WeakPolarHBondContact CG-OE2 3.35Å; R162-E165 VanDerWaalsContact CZ-CD 3.41Å; R162-E165 IonicContact CZ-OE1 2.74Å; R162-E165 VanDerWaalsContact CZ-OE1 3.31Å; R162-E165 IonicContact CZ-OE2 3.58Å; R162-E165 IonicContact NE-OE1 3.1Å; R162-E165 PolarHBondContact NE-OE1 3.38Å; R162-E165 IonicContact NE-OE2 3.49Å; R162-E165 PolarHBondContact NE-OE2 3.02Å; R162-E165 IonicContact NH2-OE1 2.7Å; R162-E165 PolarHBondContact NH2-OE1 3.4Å; R162-E165 IonicContact NH2-OE2 3.67Å; R162-E165 PolarHBondContact O-N 3.34Å; E165-C168 WeakPolarHBondContact O-CB 3.36Å; E165-C168 PolarHBondContact O-N 2.97Å; E165-Y169 WeakPolarHBondContact O-CD2 3.48Å; E165-Y169 PolarHBondContact O-N 3.45Å; E165-S282 WeakPolarHBondContact CG-OG 3.39Å
166A93.1Very high89.5Confident0 Ų023.9 Ų23.90%015%0.145CC..Hα-helixtrans-60.4-47.8171.500000112.6G154 C157 S158 R162 P163 L164 C168 Y169 H170 L190G154-A166 VanDerWaalsContact O-CB 3.24Å; G154-A166 WeakPolarHBondContact O-CB 3.42Å; C157-A166 HydrophobicContact CB-CB 3.76Å; S158-A166 WeakPolarHBondContact OG-CB 3.24Å; R162-A166 WeakPolarHBondContact O-CB 3.3Å; R162-A166 PolarHBondContact O-N 2.85Å; P163-A166 PolarHBondContact O-N 3.19Å; L164-A166 VanDerWaalsContact C-N 3.34Å; A166-C168 VanDerWaalsContact C-N 3.3Å; A166-C168 PolarHBondContact O-N 3.32Å; A166-Y169 PolarHBondContact O-N 2.87Å; A166-H170 PolarHBondContact O-CD2 2.86Å; A166-H170 PolarHBondContact O-N 3.4Å; A166-L190 HydrophobicContact CB-CD1 3.61Å
167A93.4Very high89.3Confident0 Ų031 Ų310%018%0.175CC..Hα-helixtrans-59.3-41.817600000111.8P163 L164 H170 L171 F187 L190 L226 I286P163-A167 VanDerWaalsContact O-CB 3.23Å; P163-A167 WeakPolarHBondContact O-CB 3.44Å; P163-A167 PolarHBondContact O-N 2.83Å; L164-A167 PolarHBondContact O-N 3Å; A167-H170 PolarHBondContact O-N 3.35Å; A167-L171 VanDerWaalsContact O-CB 3.27Å; A167-L171 WeakPolarHBondContact O-CB 3.34Å; A167-L171 PolarHBondContact O-N 2.85Å; A167-F187 HydrophobicContact CB-CD2 4.46Å; A167-F187 HydrophobicContact CB-CE2 3.96Å; A167-F187 WeakPolarHBondContact O-CD2 3.47Å; A167-F187 WeakPolarHBondContact O-CE2 3.5Å; A167-L190 HydrophobicContact CB-CD1 4.44Å; A167-L190 HydrophobicContact CB-CD2 3.91Å; A167-L226 HydrophobicContact CB-CD2 3.32Å; A167-I286 HydrophobicContact CB-CD1 3.85Å
168C92.1Very high89.2Confident6 Ų635.1 Ų35.14%0.04120%0.195CC..Hα-helixtrans-59.8-48.9175.7-179.40000111.5L164 E165 A166 L171 R172 I286L164-C168 WeakPolarHBondContact O-CB 3.16Å; L164-C168 PolarHBondContact O-N 3.35Å; E165-C168 WeakPolarHBondContact O-CB 3.36Å; E165-C168 PolarHBondContact O-N 2.97Å; A166-C168 VanDerWaalsContact C-N 3.3Å; A166-C168 PolarHBondContact O-N 3.32Å; C168-L171 PolarHBondContact O-N 3.21Å; C168-R172 VanDerWaalsContact O-CG 3.27Å; C168-R172 WeakPolarHBondContact O-CG 3.27Å; C168-R172 PolarHBondContact O-N 3.39Å; C168-I286 HydrophobicContact CB-CD1 4.08Å; C168-I286 HydrophobicContact CB-CG1 3.92Å
169Y93Very high89.2Confident25 Ų2539.4 Ų39.410%0.09820%0.202CC..Hα-helixtrans-63.6-46177.4-73.7-56.3000112.6F150 L153 C157 E165 A166 L171 R172 G173F150-Y169 WeakPolarHBondContact CB-O 3.34Å; F150-Y169 HydrophobicContact CD1-CD1 4.14Å; L153-Y169 HydrophobicContact CB-CD1 3.89Å; L153-Y169 HydrophobicContact CB-CD2 3.69Å; L153-Y169 HydrophobicContact CB-CE1 4.06Å; L153-Y169 HydrophobicContact CB-CE2 3.85Å; L153-Y169 HydrophobicContact CB-CG 3.7Å; L153-Y169 HydrophobicContact CD1-CD1 4.04Å; L153-Y169 HydrophobicContact CD1-CE1 3.7Å; L153-Y169 HydrophobicContact CG-CE1 4.39Å; C157-Y169 VanDerWaalsContact SG-CE2 3.56Å; E165-Y169 WeakPolarHBondContact O-CD2 3.48Å; E165-Y169 PolarHBondContact O-N 3.45Å; A166-Y169 PolarHBondContact O-N 2.87Å; Y169-L171 PolarHBondContact O-N 2.94Å; Y169-R172 PolarHBondContact O-N 3.49Å; Y169-G173 PolarHBondContact O-N 3.45Å
170H94.5Very high89.5Confident3 Ų337.3 Ų37.31%0.01419%0.187CC..Hα-helixtrans-65.6-36.9179.5-67.8-52.2000112.7S151 G154 A166 A167 G173 S174 S183 Y186 F187S151-H170 PolarHBondContact O-CE1 3.41Å; G154-H170 WeakPolarHBondContact CA-NE2 3.45Å; A166-H170 PolarHBondContact O-CD2 2.86Å; A166-H170 PolarHBondContact O-N 3.4Å; A167-H170 PolarHBondContact O-N 3.35Å; H170-G173 PolarHBondContact O-N 2.97Å; H170-S174 WeakPolarHBondContact O-CB 3.37Å; H170-S174 PolarHBondContact O-N 3.03Å; H170-S183 WeakPolarHBondContact O-CB 3.35Å; H170-Y186 WeakPolarHBondContact CE1-CB 3.38Å; H170-Y186 AromaticContact CE1-CG 3.81Å; H170-Y186 WeakPolarHBondContact ND1-CB 3.4Å; H170-F187 HydrophobicContact CB-CB 3.73Å; H170-F187 HydrophobicContact CB-CD2 3.99Å; H170-F187 HydrophobicContact CB-CG 4.29Å
171L92.5Very high90.1Very high1 Ų140.7 Ų40.71%0.00520%0.203CC..Hα-helixtrans-62.1-48.6173.1179.457.7000110.8A167 C168 Y169 G173 S174 R175 F187 Y233 I286 E289 L290A167-L171 VanDerWaalsContact O-CB 3.27Å; A167-L171 WeakPolarHBondContact O-CB 3.34Å; A167-L171 PolarHBondContact O-N 2.85Å; C168-L171 PolarHBondContact O-N 3.21Å; Y169-L171 PolarHBondContact O-N 2.94Å; L171-G173 PolarHBondContact O-N 3.46Å; L171-S174 WeakPolarHBondContact O-CB 3.43Å; L171-S174 PolarHBondContact O-N 3.49Å; L171-S174 VanDerWaalsContact O-N 3.09Å; L171-S174 PolarHBondContact O-OG 3.42Å; L171-R175 WeakPolarHBondContact O-CG 3.32Å; L171-R175 PolarHBondContact O-N 3.16Å; L171-F187 HydrophobicContact CB-CD2 4.21Å; L171-F187 HydrophobicContact CB-CE1 4.32Å; L171-F187 HydrophobicContact CB-CE2 3.86Å; L171-F187 HydrophobicContact CB-CZ 3.92Å; L171-F187 HydrophobicContact CD1-CD1 4.36Å; L171-F187 HydrophobicContact CD1-CE1 3.82Å; L171-F187 HydrophobicContact CD1-CZ 4.07Å; L171-F187 HydrophobicContact CD2-CZ 4.27Å; L171-F187 HydrophobicContact CG-CZ 4.32Å; L171-Y233 HydrophobicContact CD1-CD2 4.11Å; L171-Y233 HydrophobicContact CD1-CE2 3.96Å; L171-I286 HydrophobicContact CD2-CB 4.3Å; L171-I286 HydrophobicContact CD2-CG1 4.32Å; L171-I286 HydrophobicContact CD2-CG2 4.04Å; L171-E289 HydrophobicContact CD2-CB 3.7Å; L171-E289 HydrophobicContact CG-CB 4.17Å; L171-L290 HydrophobicContact CD2-CD2 4.47Å; L171-L290 HydrophobicContact CD2-CG 4.23Å
172R90Very high90.4Very high10 Ų1040.8 Ų40.84%0.03819%0.189CC..Hα-helixtrans-60.6-44.4177.4-7016965.3-176.78.8112.3F150 C168 Y169 S174 R175 A176 C424 D427F150-R172 HydrophobicContact CD1-CB 3.85Å; F150-R172 HydrophobicContact CE1-CB 3.74Å; F150-R172 HydrophobicContact CZ-CB 4.3Å; C168-R172 VanDerWaalsContact O-CG 3.27Å; C168-R172 WeakPolarHBondContact O-CG 3.27Å; C168-R172 PolarHBondContact O-N 3.39Å; Y169-R172 PolarHBondContact O-N 3.49Å; R172-S174 VanDerWaalsContact C-N 3.26Å; R172-S174 PolarHBondContact O-N 2.94Å; R172-R175 CarbonylContact O-C 3.01Å; R172-R175 WeakPolarHBondContact O-CA 3.39Å; R172-R175 WeakPolarHBondContact O-CB 3.46Å; R172-R175 PolarHBondContact O-N 2.96Å; R172-A176 PolarHBondContact O-N 3.16Å; R172-C424 PolarHBondContact NH1-O 3.47Å; R172-C424 PolarHBondContact NH2-O 2.99Å; R172-D427 IonicContact CZ-OD1 2.65Å; R172-D427 IonicContact CZ-OD2 3.03Å; R172-D427 VanDerWaalsContact NE-CG 3.34Å; R172-D427 IonicContact NE-OD1 3.94Å; R172-D427 PolarHBondContact NE-OD1 3.01Å; R172-D427 VanDerWaalsContact NE-OD1 3.13Å; R172-D427 IonicContact NE-OD2 3.71Å; R172-D427 PolarHBondContact NE-OD2 3.32Å; R172-D427 IonicContact NH2-OD1 3.98Å; R172-D427 PolarHBondContact NH2-OD1 2.91Å; R172-D427 IonicContact NH2-OD2 3.32Å; R172-D427 PolarHBondContact NH2-OD2 3.35Å; R172-D427 VanDerWaalsContact NH2-OD2 3.16Å
173G91.9Very high90.7Very high0 Ų037.9 Ų37.90%018%0.178CC..Hα-helixtrans-63.2-29.617500000113.7S147 Y169 H170 L171 R175 A176 S183S147-G173 WeakPolarHBondContact CB-O 3.12Å; S147-G173 PolarHBondContact OG-O 3.28Å; Y169-G173 PolarHBondContact O-N 3.45Å; H170-G173 PolarHBondContact O-N 2.97Å; L171-G173 PolarHBondContact O-N 3.46Å; G173-R175 PolarHBondContact O-N 3.35Å; G173-A176 VanDerWaalsContact O-CB 3.3Å; G173-A176 WeakPolarHBondContact O-CB 3.34Å; G173-A176 PolarHBondContact O-N 2.87Å; G173-S183 WeakPolarHBondContact CA-OG 3.47Å
174S91.8Very high90.9Very high17 Ų1737.6 Ų37.612%0.11918%0.177CC..Hα-helixtrans-70.4-17.7173.478.90000113.3H170 L171 R172 P180 S184H170-S174 WeakPolarHBondContact O-CB 3.37Å; H170-S174 PolarHBondContact O-N 3.03Å; L171-S174 WeakPolarHBondContact O-CB 3.43Å; L171-S174 PolarHBondContact O-N 3.49Å; L171-S174 VanDerWaalsContact O-N 3.09Å; L171-S174 PolarHBondContact O-OG 3.42Å; R172-S174 VanDerWaalsContact C-N 3.26Å; R172-S174 PolarHBondContact O-N 2.94Å; S174-P180 WeakPolarHBondContact O-CB 3.22Å; S174-S184 WeakPolarHBondContact CB-OG 2.81Å
175R88.3Confident91Very high79 Ų7944 Ų4430%0.29821%0.207SC..THydrogen-bonded Turntrans-100.4-4.1178.6-58-76.3-73.8158.83.3112.4L171 R172 G173 E289 E296L171-R175 WeakPolarHBondContact O-CG 3.32Å; L171-R175 PolarHBondContact O-N 3.16Å; R172-R175 CarbonylContact O-C 3.01Å; R172-R175 WeakPolarHBondContact O-CA 3.39Å; R172-R175 WeakPolarHBondContact O-CB 3.46Å; R172-R175 PolarHBondContact O-N 2.96Å; G173-R175 PolarHBondContact O-N 3.35Å; R175-E289 IonicContact NE-OE2 2.76Å; R175-E289 PolarHBondContact NE-OE2 3.47Å; R175-E296 IonicContact CZ-OE1 3.35Å; R175-E296 IonicContact CZ-OE2 3.18Å; R175-E296 IonicContact NH1-OE1 3.38Å; R175-E296 IonicContact NH1-OE2 3.16Å; R175-E296 PolarHBondContact NH1-OE2 2.96Å; R175-E296 IonicContact NH2-OE1 3.69Å; R175-E296 PolarHBondContact NH2-OE1 3.33Å; R175-E296 IonicContact NH2-OE2 2.87Å; R175-E296 PolarHBondContact NH2-OE2 3.34Å; R175-E296 VanDerWaalsContact NH2-OE2 3.07Å
176A87.6Confident91.2Very high12 Ų1247.4 Ų47.410%0.09922%0.22CC..  trans-62.514717600000110.9D145 R172 G173 E178D145-A176 WeakPolarHBondContact O-CB 3.24Å; R172-A176 PolarHBondContact O-N 3.16Å; G173-A176 VanDerWaalsContact O-CB 3.3Å; G173-A176 WeakPolarHBondContact O-CB 3.34Å; G173-A176 PolarHBondContact O-N 2.87Å; A176-E178 VanDerWaalsContact C-N 3.32Å; A176-E178 PolarHBondContact O-N 2.78Å
177K87.1Confident91.2Very high157 Ų15747.4 Ų47.468%0.68322%0.22SC*.SBendtrans-70.7-32.2-178.4-60.1-176.4-169126.40112D145D145-K177 HydrophobicContact CB-CB 4.25Å; D145-K177 HydrophobicContact CB-CD 4.41Å; D145-K177 HydrophobicContact CB-CG 4.46Å; D145-K177 PolarHBondContact O-N 3.38Å; D145-K177 WeakPolarHBondContact OD1-CE 3.44Å; D145-K177 IonicContact OD1-NZ 2.78Å; D145-K177 PolarHBondContact OD1-NZ 3.39Å; D145-K177 IonicContact OD2-NZ 3.9Å; D145-K177 PolarHBondContact OD2-NZ 2.93Å
178E87.6Confident91.2Very high87 Ų8749.9 Ų49.941%0.40724%0.237SC..BIsolated β-bridgetrans-110.6126.6-175.7-61.9-175.6-177.500111.2K143 D145 E146 S147 A176K143-E178 IonicContact NZ-OE2 3.57Å; D145-E178 PolarHBondContact O-N 3.27Å; E146-E178 HydrophobicContact CG-CB 4.43Å; S147-E178 WeakPolarHBondContact CB-O 3.38Å; S147-E178 PolarHBondContact N-O 2.9Å; S147-E178 VanDerWaalsContact N-O 3.09Å; A176-E178 VanDerWaalsContact C-N 3.32Å; A176-E178 PolarHBondContact O-N 2.78Å
179R87.1Confident91.2Very high147 Ų14754.8 Ų54.856%0.55526%0.262SS*.  trans52.347.9175.1-51.6-176.4-173.7100-1.9115.5E146 S147 D181E146-R179 IonicContact OE1-CZ 3.16Å; E146-R179 IonicContact OE1-NH1 2.91Å; E146-R179 PolarHBondContact OE1-NH1 2.76Å; E146-R179 IonicContact OE2-CZ 2.8Å; E146-R179 IonicContact OE2-NH1 2.65Å; E146-R179 PolarHBondContact OE2-NH1 2.56Å; S147-R179 WeakPolarHBondContact CB-O 3.2Å; S147-R179 PolarHBondContact OG-O 3.44Å; R179-D181 PolarHBondContact O-N 2.86Å; R179-D181 VanDerWaalsContact O-N 3.13Å
180P90.5Very high91.2Very high37 Ų3754.7 Ų54.724%0.2426%0.263CS..THydrogen-bonded Turntrans-66.4-15.9-176.129.3-36.6000114.6S174 E182 S183 S184S174-P180 WeakPolarHBondContact O-CB 3.22Å; P180-E182 PolarHBondContact O-N 3.46Å; P180-S183 PolarHBondContact O-N 3.31Å; P180-S184 WeakPolarHBondContact O-CB 3.44Å; P180-S184 PolarHBondContact O-N 3.42Å; P180-S184 PolarHBondContact O-OG 3.2Å
181D91.5Very high91.1Very high112 Ų11254.7 Ų54.760%0.59926%0.264SS*.Hα-helixtrans-58.5-42.1-171.2-63.2-28.9000113.1R179 S184 Q185R179-D181 PolarHBondContact O-N 2.86Å; R179-D181 VanDerWaalsContact O-N 3.13Å; D181-S184 PolarHBondContact O-N 3.17Å; D181-Q185 VanDerWaalsContact O-CG 3.28Å; D181-Q185 WeakPolarHBondContact O-CG 3.23Å; D181-Q185 PolarHBondContact O-N 3.1Å
182E90.2Very high91Very high58 Ų5858.2 Ų58.227%0.27129%0.285SS..Hα-helixtrans-62.8-49.8-178.4-174.8-174.3-160.200110.9S151 R152 P180 S184 Q185 Y186S151-E182 PolarHBondContact OG-OE2 2.65Å; R152-E182 IonicContact NH2-OE1 3.72Å; P180-E182 PolarHBondContact O-N 3.46Å; E182-S184 VanDerWaalsContact C-N 3.33Å; E182-S184 PolarHBondContact O-N 3.29Å; E182-Q185 PolarHBondContact O-N 2.97Å; E182-Y186 HydrophobicContact CG-CD2 3.84Å; E182-Y186 HydrophobicContact CG-CE2 3.5Å; E182-Y186 VanDerWaalsContact CG-CE2 3.5Å; E182-Y186 WeakPolarHBondContact O-CD2 3.49Å; E182-Y186 PolarHBondContact O-N 2.77Å
183S93Very high91.1Very high0 Ų061.3 Ų61.30%030%0.3CS..Hα-helixtrans-64.6-37.5177.3-85.20000112.4S147 S151 H170 G173 P180 Q185 Y186 F187S147-S183 VanDerWaalsContact OG-CB 3.24Å; S147-S183 WeakPolarHBondContact OG-CB 3.46Å; S147-S183 PolarHBondContact OG-OG 2.73Å; S147-S183 VanDerWaalsContact OG-OG 3.06Å; S151-S183 PolarHBondContact N-OG 3.28Å; S151-S183 PolarHBondContact OG-N 3.02Å; S151-S183 PolarHBondContact OG-OG 2.79Å; H170-S183 WeakPolarHBondContact O-CB 3.35Å; G173-S183 WeakPolarHBondContact CA-OG 3.47Å; P180-S183 PolarHBondContact O-N 3.31Å; S183-Q185 VanDerWaalsContact C-N 3.34Å; S183-Q185 PolarHBondContact O-N 3.46Å; S183-Y186 PolarHBondContact O-N 3.33Å; S183-F187 WeakPolarHBondContact O-CB 3.37Å; S183-F187 PolarHBondContact O-N 3.28Å
184S92.5Very high91.1Very high28 Ų2861.7 Ų61.720%0.19630%0.302CS..Hα-helixtrans-61.7-41.7176.6-55.40000112.2S174 P180 D181 E182 S188S174-S184 WeakPolarHBondContact CB-OG 2.81Å; P180-S184 WeakPolarHBondContact O-CB 3.44Å; P180-S184 PolarHBondContact O-N 3.42Å; P180-S184 PolarHBondContact O-OG 3.2Å; D181-S184 PolarHBondContact O-N 3.17Å; E182-S184 VanDerWaalsContact C-N 3.33Å; E182-S184 PolarHBondContact O-N 3.29Å; S184-S188 WeakPolarHBondContact O-CB 3.38Å; S184-S188 PolarHBondContact O-N 3.46Å; S184-S188 PolarHBondContact O-OG 2.79Å
185Q93.4Very high90.9Very high138 Ų13863.4 Ų63.465%0.64531%0.308SS*.Hα-helixtrans-65.5-46.9175.7-71.9173.227.200111.4D181 E182 S183 F187 S188 L189D181-Q185 VanDerWaalsContact O-CG 3.28Å; D181-Q185 WeakPolarHBondContact O-CG 3.23Å; D181-Q185 PolarHBondContact O-N 3.1Å; E182-Q185 PolarHBondContact O-N 2.97Å; S183-Q185 VanDerWaalsContact C-N 3.34Å; S183-Q185 PolarHBondContact O-N 3.46Å; Q185-F187 VanDerWaalsContact C-N 3.35Å; Q185-F187 PolarHBondContact O-N 3.13Å; Q185-S188 PolarHBondContact O-N 3.09Å; Q185-L189 WeakPolarHBondContact O-CB 3.34Å; Q185-L189 PolarHBondContact O-N 3.49Å
186Y93.9Very high90.9Very high79 Ų7965.7 Ų65.731%0.3132%0.317SS..Hα-helixtrans-63.7-38.8176.8-77-59.2000112.7M155 H170 E182 S183 L189 L190M155-Y186 HydrophobicContact CE-CE2 4.34Å; M155-Y186 HydrophobicContact CG-CE1 4.31Å; M155-Y186 HydrophobicContact CG-CE2 4.48Å; M155-Y186 HydrophobicContact SD-CE1 4.2Å; M155-Y186 HydrophobicContact SD-CE2 4.17Å; H170-Y186 WeakPolarHBondContact CE1-CB 3.38Å; H170-Y186 AromaticContact CE1-CG 3.81Å; H170-Y186 WeakPolarHBondContact ND1-CB 3.4Å; E182-Y186 HydrophobicContact CG-CD2 3.84Å; E182-Y186 HydrophobicContact CG-CE2 3.5Å; E182-Y186 VanDerWaalsContact CG-CE2 3.5Å; E182-Y186 WeakPolarHBondContact O-CD2 3.49Å; E182-Y186 PolarHBondContact O-N 2.77Å; S183-Y186 PolarHBondContact O-N 3.33Å; Y186-L189 PolarHBondContact O-N 3.35Å; Y186-L190 VanDerWaalsContact O-CB 3.29Å; Y186-L190 WeakPolarHBondContact O-CB 3.27Å; Y186-L190 PolarHBondContact O-N 2.88Å
187F94.1Very high90.9Very high0 Ų068.2 Ų68.20%033%0.326CS..Hα-helixtrans-61-49.2175.4-169.7-126.5000111A167 H170 L171 S183 Q185 L189 L190 L191 Y233A167-F187 HydrophobicContact CB-CD2 4.46Å; A167-F187 HydrophobicContact CB-CE2 3.96Å; A167-F187 WeakPolarHBondContact O-CD2 3.47Å; A167-F187 WeakPolarHBondContact O-CE2 3.5Å; H170-F187 HydrophobicContact CB-CB 3.73Å; H170-F187 HydrophobicContact CB-CD2 3.99Å; H170-F187 HydrophobicContact CB-CG 4.29Å; L171-F187 HydrophobicContact CB-CD2 4.21Å; L171-F187 HydrophobicContact CB-CE1 4.32Å; L171-F187 HydrophobicContact CB-CE2 3.86Å; L171-F187 HydrophobicContact CB-CZ 3.92Å; L171-F187 HydrophobicContact CD1-CD1 4.36Å; L171-F187 HydrophobicContact CD1-CE1 3.82Å; L171-F187 HydrophobicContact CD1-CZ 4.07Å; L171-F187 HydrophobicContact CD2-CZ 4.27Å; L171-F187 HydrophobicContact CG-CZ 4.32Å; S183-F187 WeakPolarHBondContact O-CB 3.37Å; S183-F187 PolarHBondContact O-N 3.28Å; Q185-F187 VanDerWaalsContact C-N 3.35Å; Q185-F187 PolarHBondContact O-N 3.13Å; F187-L189 VanDerWaalsContact C-N 3.34Å; F187-L189 PolarHBondContact O-N 3.1Å; F187-L190 PolarHBondContact O-N 3.09Å; F187-L191 HydrophobicContact CD1-CD1 3.71Å; F187-L191 HydrophobicContact CD2-CD1 4.28Å; F187-L191 HydrophobicContact CD2-CG 4.39Å; F187-L191 HydrophobicContact CE1-CD1 3.42Å; F187-L191 VanDerWaalsContact CE1-CD1 3.42Å; F187-L191 HydrophobicContact CE1-CG 4.43Å; F187-L191 HydrophobicContact CE2-CD1 4.02Å; F187-L191 HydrophobicContact CE2-CD2 4.29Å; F187-L191 HydrophobicContact CE2-CG 4.19Å; F187-L191 HydrophobicContact CG-CD1 4.14Å; F187-L191 HydrophobicContact CZ-CD1 3.6Å; F187-L191 HydrophobicContact CZ-CD2 4.3Å; F187-L191 HydrophobicContact CZ-CG 4.22Å; F187-L191 WeakPolarHBondContact O-CB 3.38Å; F187-L191 VanDerWaalsContact O-CG 3.25Å; F187-L191 WeakPolarHBondContact O-CG 3.06Å; F187-L191 PolarHBondContact O-N 3.48Å; F187-Y233 AromaticContact CD1-CD1 3.85Å; F187-Y233 HydrophobicContact CD1-CD1 3.85Å; F187-Y233 HydrophobicContact CD1-CD2 4.08Å; F187-Y233 AromaticContact CD1-CE1 3.66Å; F187-Y233 HydrophobicContact CD1-CE1 3.66Å; F187-Y233 AromaticContact CD1-CE2 3.89Å; F187-Y233 HydrophobicContact CD1-CE2 3.89Å; F187-Y233 HydrophobicContact CD1-CG 4.06Å; F187-Y233 AromaticContact CD1-CZ 3.67Å; F187-Y233 AromaticContact CE1-CD1 3.78Å; F187-Y233 HydrophobicContact CE1-CD1 3.78Å; F187-Y233 AromaticContact CE1-CD2 3.57Å; F187-Y233 HydrophobicContact CE1-CD2 3.57Å; F187-Y233 HydrophobicContact CE1-CE1 4.03Å; F187-Y233 AromaticContact CE1-CE2 3.82Å; F187-Y233 HydrophobicContact CE1-CE2 3.82Å; F187-Y233 AromaticContact CE1-CG 3.53Å; F187-Y233 HydrophobicContact CE1-CG 3.53Å
188S92.2Very high90.9Very high52 Ų5261.1 Ų61.136%0.36430%0.295SS..Hα-helixtrans-61.5-41.2178.7-590000112.1S184 Q185 T192S184-S188 WeakPolarHBondContact O-CB 3.38Å; S184-S188 PolarHBondContact O-N 3.46Å; S184-S188 PolarHBondContact O-OG 2.79Å; Q185-S188 PolarHBondContact O-N 3.09Å; S188-T192 WeakPolarHBondContact O-CB 3.47Å; S188-T192 PolarHBondContact O-N 3.1Å; S188-T192 PolarHBondContact O-OG1 3.01Å
189L92.9Very high90.9Very high108 Ų10862.5 Ų62.557%0.56530%0.298SS*.Hα-helixtrans-64.3-46.3175.9-179.164.3000111.7Q185 Y186 F187 L191 T192 E193Q185-L189 WeakPolarHBondContact O-CB 3.34Å; Q185-L189 PolarHBondContact O-N 3.49Å; Y186-L189 PolarHBondContact O-N 3.35Å; F187-L189 VanDerWaalsContact C-N 3.34Å; F187-L189 PolarHBondContact O-N 3.1Å; L189-L191 PolarHBondContact O-N 3.21Å; L189-T192 WeakPolarHBondContact O-CB 3.44Å; L189-T192 PolarHBondContact O-N 3.31Å; L189-T192 VanDerWaalsContact O-N 3.15Å; L189-E193 PolarHBondContact O-N 3.11Å
190L93.5Very high90.8Very high24 Ų2458.9 Ų58.913%0.12629%0.289CS..Hα-helixtrans-59.7-46.2178.3-178.2155.4000111.1A166 A167 Y186 F187 T192 E193 N194 L226A166-L190 HydrophobicContact CB-CD1 3.61Å; A167-L190 HydrophobicContact CB-CD1 4.44Å; A167-L190 HydrophobicContact CB-CD2 3.91Å; Y186-L190 VanDerWaalsContact O-CB 3.29Å; Y186-L190 WeakPolarHBondContact O-CB 3.27Å; Y186-L190 PolarHBondContact O-N 2.88Å; F187-L190 PolarHBondContact O-N 3.09Å; L190-T192 VanDerWaalsContact C-N 3.28Å; L190-T192 PolarHBondContact O-N 2.89Å; L190-E193 PolarHBondContact O-N 3.41Å; L190-N194 WeakPolarHBondContact O-CB 3.1Å; L190-N194 PolarHBondContact O-N 3.03Å; L190-L226 HydrophobicContact CD2-CD1 3.98Å; L190-L226 HydrophobicContact CD2-CD2 4.25Å
191L91.7Very high90.4Very high3 Ų357.4 Ų57.42%0.01628%0.279CS..Hα-helixtrans-65.7-31.7177.3-67.9173.3000112.5F187 L189 E195 L226 A229 R230 Y233F187-L191 HydrophobicContact CD1-CD1 3.71Å; F187-L191 HydrophobicContact CD2-CD1 4.28Å; F187-L191 HydrophobicContact CD2-CG 4.39Å; F187-L191 HydrophobicContact CE1-CD1 3.42Å; F187-L191 VanDerWaalsContact CE1-CD1 3.42Å; F187-L191 HydrophobicContact CE1-CG 4.43Å; F187-L191 HydrophobicContact CE2-CD1 4.02Å; F187-L191 HydrophobicContact CE2-CD2 4.29Å; F187-L191 HydrophobicContact CE2-CG 4.19Å; F187-L191 HydrophobicContact CG-CD1 4.14Å; F187-L191 HydrophobicContact CZ-CD1 3.6Å; F187-L191 HydrophobicContact CZ-CD2 4.3Å; F187-L191 HydrophobicContact CZ-CG 4.22Å; F187-L191 WeakPolarHBondContact O-CB 3.38Å; F187-L191 VanDerWaalsContact O-CG 3.25Å; F187-L191 WeakPolarHBondContact O-CG 3.06Å; F187-L191 PolarHBondContact O-N 3.48Å; L189-L191 PolarHBondContact O-N 3.21Å; L191-E195 PolarHBondContact O-N 3.11Å; L191-L226 HydrophobicContact CD2-CB 4.29Å; L191-L226 HydrophobicContact CD2-CD2 4.25Å; L191-L226 VanDerWaalsContact CD2-O 3.27Å; L191-L226 WeakPolarHBondContact CD2-O 3.48Å; L191-A229 HydrophobicContact CD2-CB 4.31Å; L191-R230 HydrophobicContact CB-CB 3.97Å; L191-R230 HydrophobicContact CB-CG 4Å; L191-R230 HydrophobicContact CD1-CB 4.13Å; L191-R230 HydrophobicContact CD1-CG 4.41Å; L191-R230 HydrophobicContact CD2-CB 4.05Å; L191-R230 HydrophobicContact CG-CB 4.28Å; L191-R230 WeakPolarHBondContact O-CD 3.42Å; L191-R230 PolarHBondContact O-NH1 3.03Å; L191-R230 VanDerWaalsContact O-NH1 3.13Å; L191-Y233 HydrophobicContact CD1-CD1 4.33Å
192T90.7Very high89.9Confident74 Ų7453.2 Ų53.245%0.45426%0.261SS..Hα-helixtrans-68.3-50.5174.7-57.30000111.6S188 L189 L190 N194 E195 R230S188-T192 WeakPolarHBondContact O-CB 3.47Å; S188-T192 PolarHBondContact O-N 3.1Å; S188-T192 PolarHBondContact O-OG1 3.01Å; L189-T192 WeakPolarHBondContact O-CB 3.44Å; L189-T192 PolarHBondContact O-N 3.31Å; L189-T192 VanDerWaalsContact O-N 3.15Å; L190-T192 VanDerWaalsContact C-N 3.28Å; L190-T192 PolarHBondContact O-N 2.89Å; T192-N194 VanDerWaalsContact C-N 3.31Å; T192-N194 PolarHBondContact O-N 2.9Å; T192-E195 PolarHBondContact O-N 3.32Å; T192-R230 VanDerWaalsContact CA-NH1 3.33Å
193E91.4Very high89.4Confident76 Ų7656.7 Ų56.736%0.35528%0.277SS..Hα-helixtrans-65-36.9178.5-171.157.2-153.400111.8L189 L190 E195 R196 H197L189-E193 PolarHBondContact O-N 3.11Å; L190-E193 PolarHBondContact O-N 3.41Å; E193-E195 VanDerWaalsContact C-N 3.29Å; E193-E195 PolarHBondContact O-N 3.11Å; E193-R196 WeakPolarHBondContact O-CB 3.34Å; E193-R196 PolarHBondContact O-N 3.21Å; E193-R196 VanDerWaalsContact O-N 3.11Å; E193-R196 IonicContact OE1-CZ 2.82Å; E193-R196 IonicContact OE1-NE 2.71Å; E193-R196 PolarHBondContact OE1-NE 3.16Å; E193-R196 IonicContact OE1-NH2 2.62Å; E193-R196 PolarHBondContact OE1-NH2 3.23Å; E193-R196 IonicContact OE2-NE 3.4Å; E193-H197 PolarHBondContact O-CD2 3.21Å; E193-H197 PolarHBondContact O-N 3.45Å; E193-H197 VanDerWaalsContact O-N 3.12Å; E193-H197 IonicContact OE1-CD2 3.29Å; E193-H197 IonicContact OE1-NE2 3.3Å; E193-H197 PolarHBondContact OE1-NE2 3.42Å
194N91.4Very high88.6Confident8 Ų861.8 Ų61.84%0.04330%0.301CS..Hα-helixtrans-58.6-37.9176.2179.783.7000113.1L190 T192 R196 H197 H198 Y223 L226 R227L190-N194 WeakPolarHBondContact O-CB 3.1Å; L190-N194 PolarHBondContact O-N 3.03Å; T192-N194 VanDerWaalsContact C-N 3.31Å; T192-N194 PolarHBondContact O-N 2.9Å; N194-R196 VanDerWaalsContact C-N 3.3Å; N194-R196 PolarHBondContact O-N 3.45Å; N194-H197 PolarHBondContact O-N 3.36Å; N194-H198 PolarHBondContact O-N 2.96Å; N194-Y223 PolarHBondContact ND2-O 3.16Å; N194-Y223 WeakPolarHBondContact OD1-CA 3.28Å; N194-Y223 VanDerWaalsContact OD1-CD1 3.26Å; N194-Y223 WeakPolarHBondContact OD1-CD1 3.49Å; N194-L226 HydrophobicContact CB-CB 4.25Å; N194-L226 HydrophobicContact CB-CD1 4.4Å; N194-L226 VanDerWaalsContact ND2-CB 3.27Å; N194-L226 WeakPolarHBondContact ND2-CB 3.4Å; N194-L226 WeakPolarHBondContact OD1-CB 3.34Å; N194-L226 VanDerWaalsContact OD1-CD1 3.29Å; N194-L226 WeakPolarHBondContact OD1-CD1 3.38Å; N194-R227 PolarHBondContact ND2-N 3.46Å
195E87.6Confident87.6Confident52 Ų5263.5 Ų63.524%0.24330%0.303CS..Hα-helixtrans-62.6-39.8177.1179.7174.2-139.100111.2L191 T192 E193 H197 H198 Y199 R230L191-E195 PolarHBondContact O-N 3.11Å; T192-E195 PolarHBondContact O-N 3.32Å; E193-E195 VanDerWaalsContact C-N 3.29Å; E193-E195 PolarHBondContact O-N 3.11Å; E195-H197 VanDerWaalsContact C-N 3.34Å; E195-H197 PolarHBondContact O-N 3.45Å; E195-H198 PolarHBondContact O-N 3.47Å; E195-Y199 HydrophobicContact CG-CD2 3.97Å; E195-Y199 HydrophobicContact CG-CE2 3.46Å; E195-Y199 VanDerWaalsContact CG-CE2 3.46Å; E195-Y199 WeakPolarHBondContact O-CD2 3.42Å; E195-Y199 PolarHBondContact O-N 3.31Å; E195-R230 IonicContact OE2-CZ 2.8Å; E195-R230 IonicContact OE2-NH1 3.64Å; E195-R230 PolarHBondContact OE2-NH1 3.1Å; E195-R230 IonicContact OE2-NH2 2.74Å; E195-R230 PolarHBondContact OE2-NH2 3.28Å
196R89.2Confident86.6Confident128 Ų12865.8 Ų65.848%0.48331%0.311SS..Hα-helixtrans-61-43.8173.4-167-177.274.184.33.5111.5E193 N194 Y199 L200E193-R196 WeakPolarHBondContact O-CB 3.34Å; E193-R196 PolarHBondContact O-N 3.21Å; E193-R196 VanDerWaalsContact O-N 3.11Å; E193-R196 IonicContact OE1-CZ 2.82Å; E193-R196 IonicContact OE1-NE 2.71Å; E193-R196 PolarHBondContact OE1-NE 3.16Å; E193-R196 IonicContact OE1-NH2 2.62Å; E193-R196 PolarHBondContact OE1-NH2 3.23Å; E193-R196 IonicContact OE2-NE 3.4Å; N194-R196 VanDerWaalsContact C-N 3.3Å; N194-R196 PolarHBondContact O-N 3.45Å; R196-Y199 PolarHBondContact O-N 3.13Å; R196-L200 HydrophobicContact CG-CD1 4.39Å; R196-L200 WeakPolarHBondContact O-CG 3.49Å; R196-L200 PolarHBondContact O-N 3.43Å; R196-L200 VanDerWaalsContact O-N 3.16Å
197H88.3Confident85.3Confident65 Ų6565.4 Ų65.430%0.30133%0.331SS..Hα-helixtrans-64.9-38177.1-74.2-67.7000113.3E193 N194 E195 L200 S201 Y223E193-H197 PolarHBondContact O-CD2 3.21Å; E193-H197 PolarHBondContact O-N 3.45Å; E193-H197 VanDerWaalsContact O-N 3.12Å; E193-H197 IonicContact OE1-CD2 3.29Å; E193-H197 IonicContact OE1-NE2 3.3Å; E193-H197 PolarHBondContact OE1-NE2 3.42Å; N194-H197 PolarHBondContact O-N 3.36Å; E195-H197 VanDerWaalsContact C-N 3.34Å; E195-H197 PolarHBondContact O-N 3.45Å; H197-L200 PolarHBondContact O-N 3.27Å; H197-S201 VanDerWaalsContact O-CB 3.29Å; H197-S201 WeakPolarHBondContact O-CB 3.39Å; H197-S201 PolarHBondContact O-N 2.9Å; H197-Y223 HydrophobicContact CB-CD1 4.03Å; H197-Y223 HydrophobicContact CB-CD2 4.38Å; H197-Y223 HydrophobicContact CB-CE1 3.68Å; H197-Y223 HydrophobicContact CB-CE2 4.07Å; H197-Y223 HydrophobicContact CB-CG 4.37Å
198H87.2Confident83.8Confident7 Ų767.4 Ų67.43%0.03234%0.343CS..Hα-helixtrans-58.8-49.1175.2178.3-92.7000111.4N194 E195 S201 A202 R227 E250N194-H198 PolarHBondContact O-N 2.96Å; E195-H198 PolarHBondContact O-N 3.47Å; H198-S201 PolarHBondContact O-N 3.4Å; H198-A202 WeakPolarHBondContact O-CB 3.29Å; H198-A202 PolarHBondContact O-N 2.69Å; H198-R227 PolarHBondContact CE1-NH1 2.82Å; H198-E250 IonicContact CE1-OE1 3.62Å; H198-E250 IonicContact CE1-OE2 2.68Å; H198-E250 IonicContact NE2-OE1 2.71Å; H198-E250 PolarHBondContact NE2-OE1 2.62Å; H198-E250 IonicContact NE2-OE2 3.07Å
199Y86.4Confident82.2Confident116 Ų11671 Ų7146%0.45536%0.358SS..Hα-helixtrans-63.4-44.1179.8-72.5-64.1000112.4E195 R196 A202 E203E195-Y199 HydrophobicContact CG-CD2 3.97Å; E195-Y199 HydrophobicContact CG-CE2 3.46Å; E195-Y199 VanDerWaalsContact CG-CE2 3.46Å; E195-Y199 WeakPolarHBondContact O-CD2 3.42Å; E195-Y199 PolarHBondContact O-N 3.31Å; R196-Y199 PolarHBondContact O-N 3.13Å; Y199-A202 PolarHBondContact O-N 2.74Å; Y199-E203 PolarHBondContact O-N 2.98Å
200L85.6Confident80.5Confident72 Ų7274.6 Ų74.638%0.37737%0.37SS..Hα-helixtrans-61.5-45.2176.4-69.5172.6000111.9R196 H197 A202 E203 E204R196-L200 HydrophobicContact CG-CD1 4.39Å; R196-L200 WeakPolarHBondContact O-CG 3.49Å; R196-L200 PolarHBondContact O-N 3.43Å; R196-L200 VanDerWaalsContact O-N 3.16Å; H197-L200 PolarHBondContact O-N 3.27Å; L200-A202 VanDerWaalsContact C-N 3.3Å; L200-A202 PolarHBondContact O-N 3.15Å; L200-E203 PolarHBondContact O-N 3.42Å; L200-E204 WeakPolarHBondContact O-CG 2.98Å; L200-E204 PolarHBondContact O-N 2.87Å
201S81.5Confident78.5Confident5 Ų584.3 Ų84.34%0.03541%0.405CS..Hα-helixtrans-63.4-35.1176.2179.30000112.4H197 H198 R205H197-S201 VanDerWaalsContact O-CB 3.29Å; H197-S201 WeakPolarHBondContact O-CB 3.39Å; H197-S201 PolarHBondContact O-N 2.9Å; H198-S201 PolarHBondContact O-N 3.4Å; S201-R205 WeakPolarHBondContact O-CG 3.28Å; S201-R205 PolarHBondContact O-N 3.48Å; S201-R205 VanDerWaalsContact O-N 3.11Å; S201-R205 PolarHBondContact O-NE 2.96Å
202A80.8Confident76.8Confident25 Ų2590.8 Ų90.821%0.20743%0.432CS..Hα-helixtrans-68.5-35175.300000112.8H198 Y199 L200H198-A202 WeakPolarHBondContact O-CB 3.29Å; H198-A202 PolarHBondContact O-N 2.69Å; Y199-A202 PolarHBondContact O-N 2.74Å; L200-A202 VanDerWaalsContact C-N 3.3Å; L200-A202 PolarHBondContact O-N 3.15Å
203E80.1Confident75.3Confident131 Ų13189 Ų8961%0.61242%0.421SS*.Hα-helixtrans-69.2-43.6173.7-72-175.9165.300111.9Y199 L200 R205 K206Y199-E203 PolarHBondContact O-N 2.98Å; L200-E203 PolarHBondContact O-N 3.42Å; E203-R205 VanDerWaalsContact C-N 3.33Å; E203-R205 PolarHBondContact O-N 3.39Å; E203-K206 WeakPolarHBondContact O-CB 3.12Å; E203-K206 PolarHBondContact O-N 3.33Å; E203-K206 VanDerWaalsContact O-N 3.11Å
204E75.8Confident73.6Confident106 Ų10688 Ų8850%0.49542%0.417SS..Hα-helixtrans-59.9-42.5176.9-72.5-179.8176.500111.9L200 K206 G207 T208 H216L200-E204 WeakPolarHBondContact O-CG 2.98Å; L200-E204 PolarHBondContact O-N 2.87Å; E204-K206 PolarHBondContact O-N 3.28Å; E204-K206 VanDerWaalsContact O-N 3.16Å; E204-G207 PolarHBondContact O-N 3.14Å; E204-T208 WeakPolarHBondContact O-CG2 3.37Å; E204-T208 PolarHBondContact O-N 2.83Å; E204-T208 PolarHBondContact O-OG1 3.44Å; E204-H216 IonicContact OE2-CE1 3.74Å
205R72.1Confident72Confident65 Ų6591.6 Ų91.625%0.24544%0.439CS..Hα-helixtrans-59.8-25.7177-77.4-175.7-70.7156.9-3.6113.6S201 E203 G207 H216 E250S201-R205 WeakPolarHBondContact O-CG 3.28Å; S201-R205 PolarHBondContact O-N 3.48Å; S201-R205 VanDerWaalsContact O-N 3.11Å; S201-R205 PolarHBondContact O-NE 2.96Å; E203-R205 VanDerWaalsContact C-N 3.33Å; E203-R205 PolarHBondContact O-N 3.39Å; R205-G207 VanDerWaalsContact C-N 3.3Å; R205-H216 HydrophobicContact CG-CB 3.88Å; R205-E250 IonicContact NH2-OE1 3.73Å
206K71.8Confident71.3Confident185 Ų18590.1 Ų90.180%0.80443%0.432SS*.Hα-helixtrans-74.2-20.1175.8-67.4175-176.8174.40112.8E203 E204E203-K206 WeakPolarHBondContact O-CB 3.12Å; E203-K206 PolarHBondContact O-N 3.33Å; E203-K206 VanDerWaalsContact O-N 3.11Å; E204-K206 PolarHBondContact O-N 3.28Å; E204-K206 VanDerWaalsContact O-N 3.16Å
207G67.6Low70.7Confident72 Ų7286.3 Ų86.374%0.74242%0.419SS*.Hα-helixtrans-108.1-4.4-174.400000115.9E204 R205E204-G207 PolarHBondContact O-N 3.14Å; R205-G207 VanDerWaalsContact C-N 3.3Å
208T61.2Low70.2Confident41 Ų4183.4 Ų83.425%0.25241%0.406SS..  trans-99.7141.7-168.549.60000115.7E204 K212E204-T208 WeakPolarHBondContact O-CG2 3.37Å; E204-T208 PolarHBondContact O-N 2.83Å; E204-T208 PolarHBondContact O-OG1 3.44Å; T208-K212 HydrophobicContact CG2-CB 4.27Å; T208-K212 HydrophobicContact CG2-CD 4.02Å
209D59.7Low70Confident128 Ų12886 Ų8668%0.68442%0.418SS*.  trans-62.7149.1169.1-1653.3000112.1R211 K212D209-R211 PolarHBondContact O-N 3.16Å; D209-K212 PolarHBondContact O-N 3.43Å
210K57.5Low70Confident184 Ų18480.5 Ų80.580%0.840%0.397SS*.THydrogen-bonded Turntrans-57.9-6.3-169.3-72.8-176178.5179.30116.2T213K210-T213 WeakPolarHBondContact CA-OG1 3.15Å; K210-T213 PolarHBondContact O-OG1 3.37Å
211R50.6Low70Confident228 Ų22877.1 Ų77.186%0.8638%0.379SS*.THydrogen-bonded Turntrans-94.8-24176.7-74.5-173.7178.4-178.21113.7D209 T213D209-R211 PolarHBondContact O-N 3.16Å; R211-T213 VanDerWaalsContact C-N 3.3Å
212K55.8Low70.3Confident138 Ų13877.4 Ų77.460%0.638%0.38SS*.THydrogen-bonded Turntrans-79.1-19.1174.2-72.1-173.3175.7-175.40112.2T208 D209 E214 H216T208-K212 HydrophobicContact CG2-CB 4.27Å; T208-K212 HydrophobicContact CG2-CD 4.02Å; D209-K212 PolarHBondContact O-N 3.43Å; K212-E214 VanDerWaalsContact C-N 3.29Å; K212-E214 PolarHBondContact O-N 2.66Å; K212-H216 VanDerWaalsContact C-CD2 3.47Å; K212-H216 PolarHBondContact O-CD2 3.48Å
213T58.7Low70.7Confident36 Ų3678.3 Ų78.322%0.22138%0.378CS..Hα-helixtrans-57.9-30.9-173.122.20000115K210 R211 H216 F217K210-T213 WeakPolarHBondContact CA-OG1 3.15Å; K210-T213 PolarHBondContact O-OG1 3.37Å; R211-T213 VanDerWaalsContact C-N 3.3Å; T213-H216 WeakPolarHBondContact O-CB 2.9Å; T213-H216 PolarHBondContact O-N 3.18Å; T213-F217 WeakPolarHBondContact O-CD2 3.5Å; T213-F217 WeakPolarHBondContact O-CE2 3.25Å; T213-F217 WeakPolarHBondContact O-CG 3.49Å; T213-F217 PolarHBondContact O-N 3.3Å; T213-F217 VanDerWaalsContact O-N 3.16Å
214E57.3Low71Confident56 Ų5672.1 Ų72.126%0.26235%0.349SS..Hα-helixtrans-70.2-44.8-175.5-68.4176.2161.600114.2K212 H216 F217 L261 R265K212-E214 VanDerWaalsContact C-N 3.29Å; K212-E214 PolarHBondContact O-N 2.66Å; E214-H216 PolarHBondContact O-N 2.88Å; E214-F217 PolarHBondContact O-N 3.44Å; E214-F217 VanDerWaalsContact O-N 3.14Å; E214-L261 HydrophobicContact CB-CD1 4.32Å; E214-L261 HydrophobicContact CG-CD1 4.33Å; E214-L261 HydrophobicContact CG-CD2 4.12Å; E214-R265 VanDerWaalsContact CD-CZ 3.43Å; E214-R265 IonicContact OE1-CZ 3.98Å; E214-R265 VanDerWaalsContact OE1-CZ 3.3Å; E214-R265 IonicContact OE1-NE 2.85Å; E214-R265 IonicContact OE1-NH1 3.27Å; E214-R265 IonicContact OE1-NH2 3.88Å; E214-R265 PolarHBondContact OE1-NH2 2.96Å; E214-R265 IonicContact OE2-CZ 3.9Å; E214-R265 IonicContact OE2-NH1 3.01Å; E214-R265 PolarHBondContact OE2-NH1 3.47Å; E214-R265 IonicContact OE2-NH2 2.99Å; E214-R265 PolarHBondContact OE2-NH2 3.28Å
215V57.8Low71.6Confident83 Ų8367.3 Ų67.350%0.50333%0.328SS..Hα-helixtrans-64.3-35.6174.7178.70000110F217 S218 E219V215-F217 PolarHBondContact O-N 2.9Å; V215-S218 PolarHBondContact O-N 3.42Å; V215-S218 PolarHBondContact O-OG 2.88Å; V215-S218 VanDerWaalsContact O-OG 3.11Å; V215-E219 PolarHBondContact O-N 3.06Å
216H72.8Confident72.4Confident21 Ų2164.3 Ų64.310%0.09732%0.316CS..Hα-helixtrans-65.6-23.6175.7-68.4-58.5000113.5E204 R205 K212 T213 E214 A220E204-H216 IonicContact OE2-CE1 3.74Å; R205-H216 HydrophobicContact CG-CB 3.88Å; K212-H216 VanDerWaalsContact C-CD2 3.47Å; K212-H216 PolarHBondContact O-CD2 3.48Å; T213-H216 WeakPolarHBondContact O-CB 2.9Å; T213-H216 PolarHBondContact O-N 3.18Å; E214-H216 PolarHBondContact O-N 2.88Å; H216-A220 WeakPolarHBondContact O-CB 3.47Å; H216-A220 PolarHBondContact O-N 3.14Å
217F76.7Confident73.2Confident49 Ų4957.4 Ų57.422%0.21529%0.285CS..Hα-helixtrans-75.9-40.6178.6-72.8-62.3000112.8T213 E214 V215 A220 F221 L254 H257T213-F217 WeakPolarHBondContact O-CD2 3.5Å; T213-F217 WeakPolarHBondContact O-CE2 3.25Å; T213-F217 WeakPolarHBondContact O-CG 3.49Å; T213-F217 PolarHBondContact O-N 3.3Å; T213-F217 VanDerWaalsContact O-N 3.16Å; E214-F217 PolarHBondContact O-N 3.44Å; E214-F217 VanDerWaalsContact O-N 3.14Å; V215-F217 PolarHBondContact O-N 2.9Å; F217-A220 PolarHBondContact O-N 3.06Å; F217-F221 VanDerWaalsContact O-CB 3.27Å; F217-F221 WeakPolarHBondContact O-CB 3.2Å; F217-F221 PolarHBondContact O-N 3.42Å; F217-L254 HydrophobicContact CD1-CD2 3.76Å; F217-L254 HydrophobicContact CE1-CD2 4.4Å; F217-H257 AromaticContact CD1-CD2 3.89Å; F217-H257 AromaticContact CD2-CD2 3.15Å; F217-H257 WeakPolarHBondContact CD2-CD2 3.44Å; F217-H257 AromaticContact CD2-NE2 3.11Å; F217-H257 WeakPolarHBondContact CD2-NE2 3.42Å; F217-H257 AromaticContact CE2-CD2 3.63Å; F217-H257 AromaticContact CE2-CE1 3.79Å; F217-H257 AromaticContact CE2-NE2 3.21Å; F217-H257 WeakPolarHBondContact CE2-NE2 3.37Å; F217-H257 AromaticContact CG-CD2 3.32Å; F217-H257 WeakPolarHBondContact CG-CD2 3.32Å; F217-H257 AromaticContact CG-NE2 3.83Å; F217-H257 AromaticContact CZ-NE2 3.95Å
218S77.4Confident74Confident3 Ų354.4 Ų54.42%0.02125%0.253CS..Hα-helixtrans-66.5-44.1177.8490000111.9V215 F221 I222 D274V215-S218 PolarHBondContact O-N 3.42Å; V215-S218 PolarHBondContact O-OG 2.88Å; V215-S218 VanDerWaalsContact O-OG 3.11Å; S218-F221 PolarHBondContact O-N 2.85Å; S218-I222 VanDerWaalsContact O-CG1 3.28Å; S218-I222 WeakPolarHBondContact O-CG1 3.44Å; S218-I222 PolarHBondContact O-N 3.21Å; S218-D274 PolarHBondContact OG-OD2 3.28Å
219E83.4Confident75.1Confident63 Ų6352.7 Ų52.729%0.29424%0.242SC..Hα-helixtrans-63.9-46.8174.3-68.4179.7155.400111.6V215 F221 I222 Y223V215-E219 PolarHBondContact O-N 3.06Å; E219-F221 VanDerWaalsContact C-N 3.29Å; E219-F221 PolarHBondContact O-N 3.04Å; E219-I222 WeakPolarHBondContact O-CB 3.48Å; E219-I222 PolarHBondContact O-N 3.39Å; E219-I222 VanDerWaalsContact O-N 3.14Å; E219-Y223 HydrophobicContact CB-CE2 4.08Å; E219-Y223 VanDerWaalsContact O-CD2 3.28Å; E219-Y223 WeakPolarHBondContact O-CD2 3.41Å; E219-Y223 VanDerWaalsContact O-CG 3.27Å; E219-Y223 PolarHBondContact O-N 2.77Å
220A85.2Confident76.4Confident0 Ų049.7 Ų49.70%022%0.221CC..Hα-helixtrans-61-39.2177.600000111.9H216 F217 Y223 S224 L254H216-A220 WeakPolarHBondContact O-CB 3.47Å; H216-A220 PolarHBondContact O-N 3.14Å; F217-A220 PolarHBondContact O-N 3.06Å; A220-Y223 PolarHBondContact O-N 2.97Å; A220-S224 WeakPolarHBondContact O-CB 3.27Å; A220-S224 PolarHBondContact O-N 3.36Å; A220-L254 HydrophobicContact CB-CD1 4.1Å; A220-L254 HydrophobicContact CB-CD2 3.98Å
221F86Confident77.6Confident0 Ų041.5 Ų41.50%019%0.186CC..Hα-helixtrans-59-49.8173.9168.2-111.6000110.8F217 S218 E219 Y223 S224 S225 N251 L254 L255 I275 I280 L283F217-F221 VanDerWaalsContact O-CB 3.27Å; F217-F221 WeakPolarHBondContact O-CB 3.2Å; F217-F221 PolarHBondContact O-N 3.42Å; S218-F221 PolarHBondContact O-N 2.85Å; E219-F221 VanDerWaalsContact C-N 3.29Å; E219-F221 PolarHBondContact O-N 3.04Å; F221-Y223 PolarHBondContact O-N 2.6Å; F221-S224 PolarHBondContact O-N 2.94Å; F221-S225 WeakPolarHBondContact CE2-OG 3.34Å; F221-S225 WeakPolarHBondContact CZ-OG 3.46Å; F221-S225 WeakPolarHBondContact O-CB 3.29Å; F221-S225 PolarHBondContact O-N 3.3Å; F221-S225 PolarHBondContact O-OG 3.01Å; F221-N251 WeakPolarHBondContact CE2-OD1 3.27Å; F221-N251 PolarHBondContact O-ND2 2.85Å; F221-L254 HydrophobicContact CB-CB 3.99Å; F221-L254 HydrophobicContact CD2-CB 4.25Å; F221-L255 HydrophobicContact CD2-CB 3.93Å; F221-L255 HydrophobicContact CD2-CD1 4.25Å; F221-L255 HydrophobicContact CE1-CD1 4.1Å; F221-L255 HydrophobicContact CE2-CB 3.64Å; F221-L255 HydrophobicContact CE2-CD1 3.56Å; F221-L255 HydrophobicContact CE2-CD2 4.43Å; F221-L255 HydrophobicContact CE2-CG 4.05Å; F221-L255 HydrophobicContact CZ-CB 4.41Å; F221-L255 HydrophobicContact CZ-CD1 3.44Å; F221-L255 VanDerWaalsContact CZ-CD1 3.44Å; F221-L255 HydrophobicContact CZ-CG 4.37Å; F221-I275 HydrophobicContact CD1-CD1 3.64Å; F221-I275 HydrophobicContact CD1-CG1 4.29Å; F221-I275 HydrophobicContact CE1-CD1 4.32Å; F221-I275 HydrophobicContact CG-CD1 4.4Å; F221-I280 HydrophobicContact CE1-CD1 4.45Å; F221-L283 HydrophobicContact CE1-CD2 4.29Å; F221-L283 HydrophobicContact CZ-CD2 3.57Å
222I87Confident79Confident11 Ų1131.1 Ų31.16%0.05615%0.147CC..Hα-helixtrans-58.3-48.6178.7-69.5164.7000111P163 L164 S218 E219 S224 S225 L226 D274P163-I222 HydrophobicContact CG-CG2 3.53Å; L164-I222 HydrophobicContact CD1-CB 4.42Å; L164-I222 HydrophobicContact CD1-CG1 3.86Å; L164-I222 HydrophobicContact CD1-CG2 4.31Å; L164-I222 HydrophobicContact CG-CG1 4.44Å; L164-I222 HydrophobicContact CG-CG2 3.99Å; S218-I222 VanDerWaalsContact O-CG1 3.28Å; S218-I222 WeakPolarHBondContact O-CG1 3.44Å; S218-I222 PolarHBondContact O-N 3.21Å; E219-I222 WeakPolarHBondContact O-CB 3.48Å; E219-I222 PolarHBondContact O-N 3.39Å; E219-I222 VanDerWaalsContact O-N 3.14Å; I222-S224 PolarHBondContact O-N 3.31Å; I222-S225 PolarHBondContact O-N 3.03Å; I222-L226 HydrophobicContact CG2-CD1 4.26Å; I222-L226 PolarHBondContact O-N 3.31Å; I222-D274 HydrophobicContact CD1-CB 3.85Å
223Y89.6Confident80.3Confident44 Ų4426.5 Ų26.517%0.17313%0.126CC..Hα-helixtrans-63.6-41.9179.6-62.4-31.7000112.3N194 H197 E219 A220 F221 R227N194-Y223 PolarHBondContact ND2-O 3.16Å; N194-Y223 WeakPolarHBondContact OD1-CA 3.28Å; N194-Y223 VanDerWaalsContact OD1-CD1 3.26Å; N194-Y223 WeakPolarHBondContact OD1-CD1 3.49Å; H197-Y223 HydrophobicContact CB-CD1 4.03Å; H197-Y223 HydrophobicContact CB-CD2 4.38Å; H197-Y223 HydrophobicContact CB-CE1 3.68Å; H197-Y223 HydrophobicContact CB-CE2 4.07Å; H197-Y223 HydrophobicContact CB-CG 4.37Å; E219-Y223 HydrophobicContact CB-CE2 4.08Å; E219-Y223 VanDerWaalsContact O-CD2 3.28Å; E219-Y223 WeakPolarHBondContact O-CD2 3.41Å; E219-Y223 VanDerWaalsContact O-CG 3.27Å; E219-Y223 PolarHBondContact O-N 2.77Å; A220-Y223 PolarHBondContact O-N 2.97Å; F221-Y223 PolarHBondContact O-N 2.6Å; Y223-R227 WeakPolarHBondContact O-CB 3.23Å; Y223-R227 PolarHBondContact O-N 3.47Å
224S87.5Confident81.2Confident1 Ų126.5 Ų26.51%0.00713%0.128CC..Hα-helixtrans-62.4-42.4175.1176.50000111.4A220 F221 I222 L226 R227 V228 N251A220-S224 WeakPolarHBondContact O-CB 3.27Å; A220-S224 PolarHBondContact O-N 3.36Å; F221-S224 PolarHBondContact O-N 2.94Å; I222-S224 PolarHBondContact O-N 3.31Å; S224-L226 PolarHBondContact O-N 3.09Å; S224-R227 WeakPolarHBondContact O-CB 3.33Å; S224-R227 PolarHBondContact O-N 2.87Å; S224-R227 VanDerWaalsContact O-N 3.15Å; S224-V228 PolarHBondContact O-N 2.95Å; S224-N251 VanDerWaalsContact C-ND2 3.26Å; S224-N251 WeakPolarHBondContact CB-ND2 3.5Å; S224-N251 VanDerWaalsContact OG-CA 3.27Å; S224-N251 WeakPolarHBondContact OG-CA 3.43Å; S224-N251 WeakPolarHBondContact OG-CB 3.46Å; S224-N251 PolarHBondContact OG-ND2 3.33Å
225S87.5Confident81.6Confident6 Ų630.5 Ų30.54%0.04215%0.151CC..Hα-helixtrans-63.9-44.2-179.2-67.10000111.6F221 I222 R227 V228 A229 N251F221-S225 WeakPolarHBondContact CE2-OG 3.34Å; F221-S225 WeakPolarHBondContact CZ-OG 3.46Å; F221-S225 WeakPolarHBondContact O-CB 3.29Å; F221-S225 PolarHBondContact O-N 3.3Å; F221-S225 PolarHBondContact O-OG 3.01Å; I222-S225 PolarHBondContact O-N 3.03Å; S225-R227 VanDerWaalsContact C-N 3.31Å; S225-R227 PolarHBondContact O-N 3.44Å; S225-V228 PolarHBondContact O-N 3.44Å; S225-A229 PolarHBondContact O-N 3.38Å; S225-N251 WeakPolarHBondContact CA-ND2 3.27Å; S225-N251 PolarHBondContact N-ND2 3.43Å; S225-N251 PolarHBondContact OG-ND2 3.46Å
226L89.6Confident81.7Confident1 Ų128.2 Ų28.21%0.00514%0.137CC..Hα-helixtrans-69.6-29.4176-71.1176.3000112.4P163 L164 A167 L190 L191 N194 I222 S224 A229 R230P163-L226 HydrophobicContact CB-CD1 3.93Å; P163-L226 HydrophobicContact CG-CD1 4.49Å; L164-L226 HydrophobicContact CD2-CD2 3.85Å; L164-L226 HydrophobicContact CD2-CG 3.93Å; A167-L226 HydrophobicContact CB-CD2 3.32Å; L190-L226 HydrophobicContact CD2-CD1 3.98Å; L190-L226 HydrophobicContact CD2-CD2 4.25Å; L191-L226 HydrophobicContact CD2-CB 4.29Å; L191-L226 HydrophobicContact CD2-CD2 4.25Å; L191-L226 VanDerWaalsContact CD2-O 3.27Å; L191-L226 WeakPolarHBondContact CD2-O 3.48Å; N194-L226 HydrophobicContact CB-CB 4.25Å; N194-L226 HydrophobicContact CB-CD1 4.4Å; N194-L226 VanDerWaalsContact ND2-CB 3.27Å; N194-L226 WeakPolarHBondContact ND2-CB 3.4Å; N194-L226 WeakPolarHBondContact OD1-CB 3.34Å; N194-L226 VanDerWaalsContact OD1-CD1 3.29Å; N194-L226 WeakPolarHBondContact OD1-CD1 3.38Å; I222-L226 HydrophobicContact CG2-CD1 4.26Å; I222-L226 PolarHBondContact O-N 3.31Å; S224-L226 PolarHBondContact O-N 3.09Å; L226-A229 PolarHBondContact O-N 2.9Å; L226-R230 WeakPolarHBondContact O-CB 3.45Å; L226-R230 PolarHBondContact O-N 3.34Å
227R87.2Confident80.8Confident40 Ų4030.1 Ų30.115%0.15116%0.156CC..Hα-helixtrans-66.2-43.1172.8-163.1-168166.3-160.4-3.6111.2N194 H198 Y223 S224 S225 R230 Y231 M247 E250N194-R227 PolarHBondContact ND2-N 3.46Å; H198-R227 PolarHBondContact CE1-NH1 2.82Å; Y223-R227 WeakPolarHBondContact O-CB 3.23Å; Y223-R227 PolarHBondContact O-N 3.47Å; S224-R227 WeakPolarHBondContact O-CB 3.33Å; S224-R227 PolarHBondContact O-N 2.87Å; S224-R227 VanDerWaalsContact O-N 3.15Å; S225-R227 VanDerWaalsContact C-N 3.31Å; S225-R227 PolarHBondContact O-N 3.44Å; R227-R230 PolarHBondContact O-N 3.23Å; R227-Y231 PolarHBondContact O-N 3.45Å; R227-Y231 VanDerWaalsContact O-N 3.15Å; R227-M247 HydrophobicContact CB-CE 4.14Å; R227-M247 HydrophobicContact CG-CE 3.57Å; R227-M247 VanDerWaalsContact O-CE 3.28Å; R227-M247 WeakPolarHBondContact O-CE 3.28Å; R227-E250 IonicContact NH1-OE2 3.33Å; R227-E250 PolarHBondContact NH1-OE2 3.34Å
228V84.5Confident79.8Confident10 Ų1035.5 Ų35.56%0.06118%0.182CC..Hα-helixtrans-61.4-48172174.60000110.4S224 S225 R230 Y231 L232 L244 M247 V248 N251S224-V228 PolarHBondContact O-N 2.95Å; S225-V228 PolarHBondContact O-N 3.44Å; V228-R230 VanDerWaalsContact C-N 3.28Å; V228-R230 PolarHBondContact O-N 3.29Å; V228-Y231 WeakPolarHBondContact O-CB 3.36Å; V228-Y231 PolarHBondContact O-N 2.93Å; V228-Y231 VanDerWaalsContact O-N 3.09Å; V228-L232 HydrophobicContact CG1-CD1 3.91Å; V228-L232 HydrophobicContact CG1-CG 4.43Å; V228-L232 WeakPolarHBondContact O-CG 3.5Å; V228-L232 PolarHBondContact O-N 3.01Å; V228-L232 VanDerWaalsContact O-N 3.09Å; V228-L244 HydrophobicContact CG1-CD1 4.42Å; V228-M247 HydrophobicContact CG2-CB 4.11Å; V228-M247 HydrophobicContact CG2-CE 4.39Å; V228-V248 HydrophobicContact CG1-CG2 4.21Å; V228-V248 HydrophobicContact CG2-CG2 4.43Å; V228-N251 HydrophobicContact CG2-CB 4.32Å
229A85.8Confident78.5Confident4 Ų439.6 Ų39.63%0.03321%0.211CC..Hα-helixtrans-56.4-41.5177.500000112.4L191 S225 L226 L232 Y233 I286 L290L191-A229 HydrophobicContact CD2-CB 4.31Å; S225-A229 PolarHBondContact O-N 3.38Å; L226-A229 PolarHBondContact O-N 2.9Å; A229-L232 PolarHBondContact O-N 3.33Å; A229-Y233 VanDerWaalsContact O-CB 3.26Å; A229-Y233 WeakPolarHBondContact O-CB 3.21Å; A229-Y233 PolarHBondContact O-N 3.36Å; A229-I286 HydrophobicContact CB-CG2 4.04Å; A229-L290 HydrophobicContact CB-CD1 3.88Å
230R86.9Confident77.5Confident65 Ų6540.8 Ų40.825%0.24522%0.216CC..Hα-helixtrans-60.7-46175.4-177.3176.2172.4-176-17.8112.5L191 T192 E195 L226 R227 V228 L232 Y233 S234L191-R230 HydrophobicContact CB-CB 3.97Å; L191-R230 HydrophobicContact CB-CG 4Å; L191-R230 HydrophobicContact CD1-CB 4.13Å; L191-R230 HydrophobicContact CD1-CG 4.41Å; L191-R230 HydrophobicContact CD2-CB 4.05Å; L191-R230 HydrophobicContact CG-CB 4.28Å; L191-R230 WeakPolarHBondContact O-CD 3.42Å; L191-R230 PolarHBondContact O-NH1 3.03Å; L191-R230 VanDerWaalsContact O-NH1 3.13Å; T192-R230 VanDerWaalsContact CA-NH1 3.33Å; E195-R230 IonicContact OE2-CZ 2.8Å; E195-R230 IonicContact OE2-NH1 3.64Å; E195-R230 PolarHBondContact OE2-NH1 3.1Å; E195-R230 IonicContact OE2-NH2 2.74Å; E195-R230 PolarHBondContact OE2-NH2 3.28Å; L226-R230 WeakPolarHBondContact O-CB 3.45Å; L226-R230 PolarHBondContact O-N 3.34Å; R227-R230 PolarHBondContact O-N 3.23Å; V228-R230 VanDerWaalsContact C-N 3.28Å; V228-R230 PolarHBondContact O-N 3.29Å; R230-L232 VanDerWaalsContact C-N 3.26Å; R230-L232 PolarHBondContact O-N 2.99Å; R230-Y233 PolarHBondContact O-N 3.49Å; R230-S234 WeakPolarHBondContact O-CB 3.47Å; R230-S234 PolarHBondContact O-N 3.18Å; R230-S234 PolarHBondContact O-OG 3.03Å
231Y81.8Confident76.5Confident13 Ų1343.3 Ų43.35%0.05123%0.23CC..Hα-helixtrans-60.7-39.1-179.7-170.1-85.3000111.9R227 V228 T236 Q240 D241 L244 M247 K301R227-Y231 PolarHBondContact O-N 3.45Å; R227-Y231 VanDerWaalsContact O-N 3.15Å; V228-Y231 WeakPolarHBondContact O-CB 3.36Å; V228-Y231 PolarHBondContact O-N 2.93Å; V228-Y231 VanDerWaalsContact O-N 3.09Å; Y231-T236 HydrophobicContact CE2-CG2 4.41Å; Y231-T236 PolarHBondContact OH-OG1 3.19Å; Y231-Q240 HydrophobicContact CE2-CB 3.95Å; Y231-Q240 WeakPolarHBondContact OH-CB 3.27Å; Y231-Q240 PolarHBondContact OH-O 2.72Å; Y231-D241 VanDerWaalsContact CE1-OD1 3.27Å; Y231-D241 WeakPolarHBondContact CE1-OD1 3.27Å; Y231-D241 VanDerWaalsContact CZ-OD1 3.3Å; Y231-D241 WeakPolarHBondContact OH-CA 3.27Å; Y231-D241 PolarHBondContact OH-N 3.3Å; Y231-D241 PolarHBondContact OH-OD1 2.92Å; Y231-L244 HydrophobicContact CD1-CB 3.94Å; Y231-L244 HydrophobicContact CD1-CD1 3.69Å; Y231-L244 HydrophobicContact CD1-CD2 4Å; Y231-L244 HydrophobicContact CD1-CG 4.08Å; Y231-L244 HydrophobicContact CE1-CB 3.8Å; Y231-L244 HydrophobicContact CE1-CD1 4.38Å; Y231-L244 HydrophobicContact CE1-CD2 4.02Å; Y231-L244 HydrophobicContact CE1-CG 4.28Å; Y231-L244 HydrophobicContact CG-CD1 4.24Å; Y231-M247 HydrophobicContact CD2-SD 4.41Å; Y231-K301 PolarHBondContact O-NZ 3.04Å
232L80.8Confident75.6Confident9 Ų950.6 Ų50.65%0.04726%0.262CS..Hα-helixtrans-75.5-37.4179-63.2172.1000112.5V228 A229 R230 L244 L290 L294 L515V228-L232 HydrophobicContact CG1-CD1 3.91Å; V228-L232 HydrophobicContact CG1-CG 4.43Å; V228-L232 WeakPolarHBondContact O-CG 3.5Å; V228-L232 PolarHBondContact O-N 3.01Å; V228-L232 VanDerWaalsContact O-N 3.09Å; A229-L232 PolarHBondContact O-N 3.33Å; R230-L232 VanDerWaalsContact C-N 3.26Å; R230-L232 PolarHBondContact O-N 2.99Å; L232-L244 HydrophobicContact CD2-CD1 4.33Å; L232-L244 HydrophobicContact CD2-CD2 3.99Å; L232-L290 HydrophobicContact CB-CD1 4.23Å; L232-L290 HydrophobicContact CB-CD2 4.45Å; L232-L290 HydrophobicContact CD1-CD1 4.16Å; L232-L294 HydrophobicContact CB-CD1 4.43Å; L232-L294 HydrophobicContact CD2-CD1 4.1Å; L232-L515 HydrophobicContact CD1-CD1 3.65Å; L232-L515 HydrophobicContact CD1-CG 4.46Å
233Y82.3Confident75.1Confident42 Ų4253.9 Ų53.917%0.16528%0.277CS..Hα-helixtrans-72.7-40.6-179.6-175.7-106.8000112.9L171 F187 L191 A229 R230 L290 L293L171-Y233 HydrophobicContact CD1-CD2 4.11Å; L171-Y233 HydrophobicContact CD1-CE2 3.96Å; F187-Y233 AromaticContact CD1-CD1 3.85Å; F187-Y233 HydrophobicContact CD1-CD1 3.85Å; F187-Y233 HydrophobicContact CD1-CD2 4.08Å; F187-Y233 AromaticContact CD1-CE1 3.66Å; F187-Y233 HydrophobicContact CD1-CE1 3.66Å; F187-Y233 AromaticContact CD1-CE2 3.89Å; F187-Y233 HydrophobicContact CD1-CE2 3.89Å; F187-Y233 HydrophobicContact CD1-CG 4.06Å; F187-Y233 AromaticContact CD1-CZ 3.67Å; F187-Y233 AromaticContact CE1-CD1 3.78Å; F187-Y233 HydrophobicContact CE1-CD1 3.78Å; F187-Y233 AromaticContact CE1-CD2 3.57Å; F187-Y233 HydrophobicContact CE1-CD2 3.57Å; F187-Y233 HydrophobicContact CE1-CE1 4.03Å; F187-Y233 AromaticContact CE1-CE2 3.82Å; F187-Y233 HydrophobicContact CE1-CE2 3.82Å; F187-Y233 AromaticContact CE1-CG 3.53Å; F187-Y233 HydrophobicContact CE1-CG 3.53Å; L191-Y233 HydrophobicContact CD1-CD1 4.33Å; A229-Y233 VanDerWaalsContact O-CB 3.26Å; A229-Y233 WeakPolarHBondContact O-CB 3.21Å; A229-Y233 PolarHBondContact O-N 3.36Å; R230-Y233 PolarHBondContact O-N 3.49Å; Y233-L290 HydrophobicContact CD2-CD2 4.2Å; Y233-L293 HydrophobicContact CD2-CD2 3.8Å; Y233-L293 HydrophobicContact CE2-CD2 4.25Å
234S78Confident74.3Confident36 Ų3652.1 Ų52.125%0.25227%0.271SS..SBendtrans-71.8144.2-177.954.70000112R230 T236R230-S234 WeakPolarHBondContact O-CB 3.47Å; R230-S234 PolarHBondContact O-N 3.18Å; R230-S234 PolarHBondContact O-OG 3.03Å; S234-T236 PolarHBondContact O-N 3.49Å; S234-T236 VanDerWaalsContact OG-CG2 3.31Å; S234-T236 WeakPolarHBondContact OG-CG2 3.41Å
235N64.8Low73.7Confident140 Ų14054.9 Ų54.975%0.74929%0.288SS*.  trans-76.851.7169.9-70.2-7.8000110A237 K297N235-A237 PolarHBondContact O-N 3.36Å; N235-K297 PolarHBondContact OD1-NZ 2.83Å
236T60Low73.3Confident34 Ų3457.9 Ų57.921%0.20931%0.313CS..  trans-58.9138174.5450000109.5Y231 S234 Q240 K301Y231-T236 HydrophobicContact CE2-CG2 4.41Å; Y231-T236 PolarHBondContact OH-OG1 3.19Å; S234-T236 PolarHBondContact O-N 3.49Å; S234-T236 VanDerWaalsContact OG-CG2 3.31Å; S234-T236 WeakPolarHBondContact OG-CG2 3.41Å; T236-Q240 VanDerWaalsContact CG2-OE1 3.28Å; T236-K301 PolarHBondContact OG1-NZ 2.78Å
237A54.6Low72.7Confident61 Ų6158.2 Ų58.250%0.50432%0.315SS..  trans-57.8142.517500000109.6N235 S239 Q240N235-A237 PolarHBondContact O-N 3.36Å; A237-S239 PolarHBondContact O-N 3.13Å; A237-Q240 PolarHBondContact O-N 3.17Å
238E55.7Low72.2Confident162 Ų16256.8 Ų56.876%0.75731%0.311SS*.G310 helixtrans-48.2-28.1179.5-62.4-178.6161.700112.7Q240 D241E238-Q240 PolarHBondContact O-N 3.39Å; E238-Q240 VanDerWaalsContact O-N 3.09Å; E238-D241 WeakPolarHBondContact O-CB 3.33Å; E238-D241 PolarHBondContact O-N 2.98Å
239S49.4Very low71.7Confident89 Ų8960.9 Ų60.962%0.62233%0.329SS*.G310 helixtrans-60.9-15.5176.5620000115.3A237 F242A237-S239 PolarHBondContact O-N 3.13Å; S239-F242 WeakPolarHBondContact O-CD1 3.48Å; S239-F242 VanDerWaalsContact O-CE1 3.26Å; S239-F242 WeakPolarHBondContact O-CE1 3.42Å
240Q62.3Low71.5Confident88 Ų8863 Ų6341%0.41134%0.338SS..G310 helixtrans-95.4-6.6176.1-65.4-175.2-700113.2Y231 T236 A237 E238 F242 Q243Y231-Q240 HydrophobicContact CE2-CB 3.95Å; Y231-Q240 WeakPolarHBondContact OH-CB 3.27Å; Y231-Q240 PolarHBondContact OH-O 2.72Å; T236-Q240 VanDerWaalsContact CG2-OE1 3.28Å; A237-Q240 PolarHBondContact O-N 3.17Å; E238-Q240 PolarHBondContact O-N 3.39Å; E238-Q240 VanDerWaalsContact O-N 3.09Å; Q240-F242 PolarHBondContact O-N 2.66Å; Q240-Q243 PolarHBondContact O-N 3Å
241D65.1Low71.3Confident54 Ų5459.9 Ų59.929%0.28933%0.327SS..G310 helixtrans-64.4-20.2-172.2-74.3-25.6000112.7Y231 E238 Q243 L244 P245 K301Y231-D241 VanDerWaalsContact CE1-OD1 3.27Å; Y231-D241 WeakPolarHBondContact CE1-OD1 3.27Å; Y231-D241 VanDerWaalsContact CZ-OD1 3.3Å; Y231-D241 WeakPolarHBondContact OH-CA 3.27Å; Y231-D241 PolarHBondContact OH-N 3.3Å; Y231-D241 PolarHBondContact OH-OD1 2.92Å; E238-D241 WeakPolarHBondContact O-CB 3.33Å; E238-D241 PolarHBondContact O-N 2.98Å; D241-Q243 PolarHBondContact O-N 3.01Å; D241-Q243 VanDerWaalsContact O-N 3.15Å; D241-L244 PolarHBondContact O-N 2.76Å; D241-P245 WeakPolarHBondContact O-CD 3.46Å; D241-K301 WeakPolarHBondContact OD1-CE 3.34Å; D241-K301 IonicContact OD1-NZ 3.51Å
242F67.5Low70.9Confident152 Ų15259.9 Ų59.967%0.66733%0.328SS*.G310 helixtrans-61.5-21173.977.7-90.3000113.9S239 Q240S239-F242 WeakPolarHBondContact O-CD1 3.48Å; S239-F242 VanDerWaalsContact O-CE1 3.26Å; S239-F242 WeakPolarHBondContact O-CE1 3.42Å; Q240-F242 PolarHBondContact O-N 2.66Å
243Q75.6Confident70.7Confident81 Ų8164.8 Ų64.838%0.37935%0.35SS..G310 helixtrans-83.7-23.7179.1-62.3-171.92.400113.1Q240 D241 A246 M247Q240-Q243 PolarHBondContact O-N 3Å; D241-Q243 PolarHBondContact O-N 3.01Å; D241-Q243 VanDerWaalsContact O-N 3.15Å; Q243-A246 PolarHBondContact O-N 3.18Å; Q243-M247 HydrophobicContact CB-SD 4.47Å; Q243-M247 WeakPolarHBondContact O-CG 3.5Å; Q243-M247 PolarHBondContact O-N 2.97Å; Q243-M247 VanDerWaalsContact O-N 3.1Å
244L73.9Confident70.7Confident7 Ų763.2 Ų63.24%0.03735%0.345CS..Hα-helixtrans-60.3-46.4-173.6177.562.2000112.8V228 Y231 L232 D241 A246 M247 V248V228-L244 HydrophobicContact CG1-CD1 4.42Å; Y231-L244 HydrophobicContact CD1-CB 3.94Å; Y231-L244 HydrophobicContact CD1-CD1 3.69Å; Y231-L244 HydrophobicContact CD1-CD2 4Å; Y231-L244 HydrophobicContact CD1-CG 4.08Å; Y231-L244 HydrophobicContact CE1-CB 3.8Å; Y231-L244 HydrophobicContact CE1-CD1 4.38Å; Y231-L244 HydrophobicContact CE1-CD2 4.02Å; Y231-L244 HydrophobicContact CE1-CG 4.28Å; Y231-L244 HydrophobicContact CG-CD1 4.24Å; L232-L244 HydrophobicContact CD2-CD1 4.33Å; L232-L244 HydrophobicContact CD2-CD2 3.99Å; D241-L244 PolarHBondContact O-N 2.76Å; L244-A246 VanDerWaalsContact C-N 3.28Å; L244-A246 PolarHBondContact O-N 2.8Å; L244-M247 PolarHBondContact O-N 2.65Å; L244-M247 VanDerWaalsContact O-N 3.13Å; L244-V248 HydrophobicContact CD1-CG2 3.78Å; L244-V248 HydrophobicContact CG-CG2 4.21Å; L244-V248 WeakPolarHBondContact O-CG2 3.37Å; L244-V248 PolarHBondContact O-N 3.26Å
245P74.5Confident70.7Confident58 Ų5861.6 Ų61.638%0.37733%0.333SS..Hα-helixtrans-57.1-40.5177.9-26.635.6000113.1D241 V248 E249D241-P245 WeakPolarHBondContact O-CD 3.46Å; P245-V248 PolarHBondContact O-N 3.42Å; P245-E249 VanDerWaalsContact O-CB 3.31Å; P245-E249 WeakPolarHBondContact O-CB 3.46Å; P245-E249 PolarHBondContact O-N 3.11Å
246A78.2Confident71.2Confident69 Ų6957.4 Ų57.457%0.5731%0.311SS*.Hα-helixtrans-68.2-37.8178.500000112.4Q243 L244 E250Q243-A246 PolarHBondContact O-N 3.18Å; L244-A246 VanDerWaalsContact C-N 3.28Å; L244-A246 PolarHBondContact O-N 2.8Å; A246-E250 WeakPolarHBondContact O-CB 3.49Å; A246-E250 PolarHBondContact O-N 3.16Å
247M78Confident71.9Confident9 Ų959 Ų594%0.04432%0.315CS..Hα-helixtrans-67.7-41.2176.1-69.5174.348.900112.1R227 V228 Y231 Q243 L244 N251R227-M247 HydrophobicContact CB-CE 4.14Å; R227-M247 HydrophobicContact CG-CE 3.57Å; R227-M247 VanDerWaalsContact O-CE 3.28Å; R227-M247 WeakPolarHBondContact O-CE 3.28Å; V228-M247 HydrophobicContact CG2-CB 4.11Å; V228-M247 HydrophobicContact CG2-CE 4.39Å; Y231-M247 HydrophobicContact CD2-SD 4.41Å; Q243-M247 HydrophobicContact CB-SD 4.47Å; Q243-M247 WeakPolarHBondContact O-CG 3.5Å; Q243-M247 PolarHBondContact O-N 2.97Å; Q243-M247 VanDerWaalsContact O-N 3.1Å; L244-M247 PolarHBondContact O-N 2.65Å; L244-M247 VanDerWaalsContact O-N 3.13Å; M247-N251 WeakPolarHBondContact O-CB 3.32Å; M247-N251 PolarHBondContact O-N 3.42Å
248V75.7Confident72.8Confident10 Ų1056.3 Ų56.36%0.06129%0.293CS..Hα-helixtrans-64.1-48.61761690000109.8V228 L244 P245 E250 N251 I252 D514 Q516V228-V248 HydrophobicContact CG1-CG2 4.21Å; V228-V248 HydrophobicContact CG2-CG2 4.43Å; L244-V248 HydrophobicContact CD1-CG2 3.78Å; L244-V248 HydrophobicContact CG-CG2 4.21Å; L244-V248 WeakPolarHBondContact O-CG2 3.37Å; L244-V248 PolarHBondContact O-N 3.26Å; P245-V248 PolarHBondContact O-N 3.42Å; V248-E250 PolarHBondContact O-N 3.32Å; V248-N251 WeakPolarHBondContact O-CB 3.37Å; V248-N251 PolarHBondContact O-N 3.27Å; V248-N251 VanDerWaalsContact O-N 3.1Å; V248-I252 HydrophobicContact CG1-CD1 3.53Å; V248-I252 HydrophobicContact CG1-CG1 4.24Å; V248-I252 WeakPolarHBondContact O-CB 3.49Å; V248-I252 WeakPolarHBondContact O-CG1 3.22Å; V248-I252 PolarHBondContact O-N 2.79Å; V248-D514 WeakPolarHBondContact CG1-O 3.3Å; V248-Q516 HydrophobicContact CG1-CG 4.48Å
249E75Confident73.6Confident96 Ų9648.7 Ų48.745%0.44926%0.257SS..Hα-helixtrans-59-45.4177.6-17957.2-152.200112.4P245 N251 I252 Q253P245-E249 VanDerWaalsContact O-CB 3.31Å; P245-E249 WeakPolarHBondContact O-CB 3.46Å; P245-E249 PolarHBondContact O-N 3.11Å; E249-N251 VanDerWaalsContact C-N 3.3Å; E249-N251 PolarHBondContact O-N 3.05Å; E249-I252 PolarHBondContact O-N 3.11Å; E249-Q253 VanDerWaalsContact O-CG 3.31Å; E249-Q253 WeakPolarHBondContact O-CG 3.41Å; E249-Q253 PolarHBondContact O-N 2.91Å; E249-Q253 PolarHBondContact OE1-NE2 3.49Å
250E81.7Confident74.6Confident48 Ų4847.8 Ų47.822%0.22424%0.243CC..Hα-helixtrans-56.1-47.2173.4-178.4-168170.600110.8H198 R205 R227 A246 V248 I252 Q253 L254H198-E250 IonicContact CE1-OE1 3.62Å; H198-E250 IonicContact CE1-OE2 2.68Å; H198-E250 IonicContact NE2-OE1 2.71Å; H198-E250 PolarHBondContact NE2-OE1 2.62Å; H198-E250 IonicContact NE2-OE2 3.07Å; R205-E250 IonicContact NH2-OE1 3.73Å; R227-E250 IonicContact NH1-OE2 3.33Å; R227-E250 PolarHBondContact NH1-OE2 3.34Å; A246-E250 WeakPolarHBondContact O-CB 3.49Å; A246-E250 PolarHBondContact O-N 3.16Å; V248-E250 PolarHBondContact O-N 3.32Å; E250-I252 PolarHBondContact O-N 3.37Å; E250-Q253 PolarHBondContact O-N 3.12Å; E250-L254 HydrophobicContact CG-CD1 3.99Å; E250-L254 VanDerWaalsContact O-CG 3.3Å; E250-L254 WeakPolarHBondContact O-CG 3.48Å; E250-L254 PolarHBondContact O-N 3.47Å
251N81.7Confident75Confident0 Ų044.3 Ų44.30%023%0.227CC..Hα-helixtrans-63.3-42.9-178.4-170.7-97000112.6F221 S224 S225 V228 M247 V248 E249 L254 L255 Q516F221-N251 WeakPolarHBondContact CE2-OD1 3.27Å; F221-N251 PolarHBondContact O-ND2 2.85Å; S224-N251 VanDerWaalsContact C-ND2 3.26Å; S224-N251 WeakPolarHBondContact CB-ND2 3.5Å; S224-N251 VanDerWaalsContact OG-CA 3.27Å; S224-N251 WeakPolarHBondContact OG-CA 3.43Å; S224-N251 WeakPolarHBondContact OG-CB 3.46Å; S224-N251 PolarHBondContact OG-ND2 3.33Å; S225-N251 WeakPolarHBondContact CA-ND2 3.27Å; S225-N251 PolarHBondContact N-ND2 3.43Å; S225-N251 PolarHBondContact OG-ND2 3.46Å; V228-N251 HydrophobicContact CG2-CB 4.32Å; M247-N251 WeakPolarHBondContact O-CB 3.32Å; M247-N251 PolarHBondContact O-N 3.42Å; V248-N251 WeakPolarHBondContact O-CB 3.37Å; V248-N251 PolarHBondContact O-N 3.27Å; V248-N251 VanDerWaalsContact O-N 3.1Å; E249-N251 VanDerWaalsContact C-N 3.3Å; E249-N251 PolarHBondContact O-N 3.05Å; N251-L254 PolarHBondContact O-N 3.31Å; N251-L255 VanDerWaalsContact O-CB 3.31Å; N251-L255 WeakPolarHBondContact O-CB 3.27Å; N251-L255 PolarHBondContact O-N 3.24Å; N251-Q516 PolarHBondContact OD1-NE2 3.43Å; N251-Q516 PolarHBondContact OD1-OE1 2.83Å
252I73.1Confident75Confident13 Ų1343.6 Ų43.67%0.06722%0.223CC..Hα-helixtrans-59.9-46.5176.8-70.9172.4000110.3V248 E249 E250 L254 L255 N256 Q516 Q519V248-I252 HydrophobicContact CG1-CD1 3.53Å; V248-I252 HydrophobicContact CG1-CG1 4.24Å; V248-I252 WeakPolarHBondContact O-CB 3.49Å; V248-I252 WeakPolarHBondContact O-CG1 3.22Å; V248-I252 PolarHBondContact O-N 2.79Å; E249-I252 PolarHBondContact O-N 3.11Å; E250-I252 PolarHBondContact O-N 3.37Å; I252-L254 VanDerWaalsContact C-N 3.32Å; I252-L254 PolarHBondContact O-N 2.81Å; I252-L255 WeakPolarHBondContact O-CB 3.36Å; I252-L255 PolarHBondContact O-N 3.03Å; I252-N256 WeakPolarHBondContact O-CB 3.1Å; I252-N256 PolarHBondContact O-N 2.93Å; I252-N256 PolarHBondContact O-ND2 2.68Å; I252-N256 PolarHBondContact O-OD1 2.79Å; I252-Q516 HydrophobicContact CD1-CG 4.42Å; I252-Q516 HydrophobicContact CG1-CG 3.94Å; I252-Q519 VanDerWaalsContact CD1-OE1 3.32Å
253Q78.5Confident75Confident112 Ų11237.1 Ų37.152%0.52320%0.196SC..Hα-helixtrans-61.2-42.4177.4-70.7174.710.100111.9E249 E250 H257E249-Q253 VanDerWaalsContact O-CG 3.31Å; E249-Q253 WeakPolarHBondContact O-CG 3.41Å; E249-Q253 PolarHBondContact O-N 2.91Å; E249-Q253 PolarHBondContact OE1-NE2 3.49Å; E250-Q253 PolarHBondContact O-N 3.12Å; Q253-H257 WeakPolarHBondContact O-CB 3.01Å; Q253-H257 PolarHBondContact O-N 3.32Å
254L80.8Confident74.5Confident9 Ų939.1 Ų39.15%0.04721%0.209CC..Hα-helixtrans-65.4-41.2176.1-69.9168.4000111.8F217 A220 F221 E250 N251 I252 H257 C258F217-L254 HydrophobicContact CD1-CD2 3.76Å; F217-L254 HydrophobicContact CE1-CD2 4.4Å; A220-L254 HydrophobicContact CB-CD1 4.1Å; A220-L254 HydrophobicContact CB-CD2 3.98Å; F221-L254 HydrophobicContact CB-CB 3.99Å; F221-L254 HydrophobicContact CD2-CB 4.25Å; E250-L254 HydrophobicContact CG-CD1 3.99Å; E250-L254 VanDerWaalsContact O-CG 3.3Å; E250-L254 WeakPolarHBondContact O-CG 3.48Å; E250-L254 PolarHBondContact O-N 3.47Å; N251-L254 PolarHBondContact O-N 3.31Å; I252-L254 VanDerWaalsContact C-N 3.32Å; I252-L254 PolarHBondContact O-N 2.81Å; L254-H257 PolarHBondContact O-N 2.8Å; L254-C258 PolarHBondContact O-N 3.38Å; L254-C258 PolarHBondContact O-SG 3.3Å
255L79.1Confident73.7Confident1 Ų144 Ų441%0.00523%0.227CC..Hα-helixtrans-60.7-50.9175.7-177.755.6000110.9F221 N251 I252 H257 C258 F259 V520F221-L255 HydrophobicContact CD2-CB 3.93Å; F221-L255 HydrophobicContact CD2-CD1 4.25Å; F221-L255 HydrophobicContact CE1-CD1 4.1Å; F221-L255 HydrophobicContact CE2-CB 3.64Å; F221-L255 HydrophobicContact CE2-CD1 3.56Å; F221-L255 HydrophobicContact CE2-CD2 4.43Å; F221-L255 HydrophobicContact CE2-CG 4.05Å; F221-L255 HydrophobicContact CZ-CB 4.41Å; F221-L255 HydrophobicContact CZ-CD1 3.44Å; F221-L255 VanDerWaalsContact CZ-CD1 3.44Å; F221-L255 HydrophobicContact CZ-CG 4.37Å; N251-L255 VanDerWaalsContact O-CB 3.31Å; N251-L255 WeakPolarHBondContact O-CB 3.27Å; N251-L255 PolarHBondContact O-N 3.24Å; I252-L255 WeakPolarHBondContact O-CB 3.36Å; I252-L255 PolarHBondContact O-N 3.03Å; L255-H257 PolarHBondContact O-N 2.85Å; L255-C258 WeakPolarHBondContact O-CB 3.21Å; L255-C258 PolarHBondContact O-N 2.8Å; L255-C258 VanDerWaalsContact O-N 3.12Å; L255-F259 HydrophobicContact CD1-CD2 3.46Å; L255-F259 VanDerWaalsContact CD1-CD2 3.46Å; L255-F259 HydrophobicContact CD1-CE2 3.16Å; L255-F259 HydrophobicContact CD1-CZ 4.25Å; L255-F259 HydrophobicContact CD2-CE2 4.2Å; L255-F259 HydrophobicContact CG-CD2 3.67Å; L255-F259 HydrophobicContact CG-CE2 3.62Å; L255-F259 VanDerWaalsContact O-CD2 3.28Å; L255-F259 WeakPolarHBondContact O-CD2 3.47Å; L255-F259 PolarHBondContact O-N 2.91Å; L255-V520 HydrophobicContact CD2-CG2 3.75Å
256N73.6Confident72.7Confident53 Ų5344.6 Ų44.628%0.28322%0.222SC..Hα-helixtrans-55.7-43.9176.7-65.3-6.4000110.1I252 F259 Q260 H523I252-N256 WeakPolarHBondContact O-CB 3.1Å; I252-N256 PolarHBondContact O-N 2.93Å; I252-N256 PolarHBondContact O-ND2 2.68Å; I252-N256 PolarHBondContact O-OD1 2.79Å; N256-F259 PolarHBondContact O-N 2.91Å; N256-Q260 WeakPolarHBondContact O-CB 3.44Å; N256-Q260 VanDerWaalsContact O-CG 3.24Å; N256-Q260 WeakPolarHBondContact O-CG 3.12Å; N256-Q260 PolarHBondContact O-N 2.69Å; N256-H523 PolarHBondContact OD1-CE1 2.96Å; N256-H523 PolarHBondContact OD1-NE2 3.15Å
257H74.8Confident70.7Confident66 Ų6650.3 Ų50.331%0.30623%0.234SC..Hα-helixtrans-63.5-45.2177.3-163.582.6000112.5F217 Q253 L254 L255 F259 Q260 L261F217-H257 AromaticContact CD1-CD2 3.89Å; F217-H257 AromaticContact CD2-CD2 3.15Å; F217-H257 WeakPolarHBondContact CD2-CD2 3.44Å; F217-H257 AromaticContact CD2-NE2 3.11Å; F217-H257 WeakPolarHBondContact CD2-NE2 3.42Å; F217-H257 AromaticContact CE2-CD2 3.63Å; F217-H257 AromaticContact CE2-CE1 3.79Å; F217-H257 AromaticContact CE2-NE2 3.21Å; F217-H257 WeakPolarHBondContact CE2-NE2 3.37Å; F217-H257 AromaticContact CG-CD2 3.32Å; F217-H257 WeakPolarHBondContact CG-CD2 3.32Å; F217-H257 AromaticContact CG-NE2 3.83Å; F217-H257 AromaticContact CZ-NE2 3.95Å; Q253-H257 WeakPolarHBondContact O-CB 3.01Å; Q253-H257 PolarHBondContact O-N 3.32Å; L254-H257 PolarHBondContact O-N 2.8Å; L255-H257 PolarHBondContact O-N 2.85Å; H257-F259 VanDerWaalsContact C-N 3.32Å; H257-F259 PolarHBondContact O-N 3.16Å; H257-Q260 PolarHBondContact O-N 3.42Å; H257-L261 WeakPolarHBondContact O-CG 3.43Å; H257-L261 PolarHBondContact O-N 2.86Å
258C74.4Confident69Low5 Ų558.7 Ų58.73%0.03427%0.27CS..Hα-helixtrans-59.5-44.2176.2-68.20000111.5L254 L255 L261 L262 I275L254-C258 PolarHBondContact O-N 3.38Å; L254-C258 PolarHBondContact O-SG 3.3Å; L255-C258 WeakPolarHBondContact O-CB 3.21Å; L255-C258 PolarHBondContact O-N 2.8Å; L255-C258 VanDerWaalsContact O-N 3.12Å; C258-L261 PolarHBondContact O-N 2.73Å; C258-L262 WeakPolarHBondContact O-CG 3.23Å; C258-L262 PolarHBondContact O-N 3.37Å; C258-I275 HydrophobicContact CB-CD1 3.5Å; C258-I275 WeakPolarHBondContact SG-CD1 3.49Å
259F72.3Confident67.3Low3 Ų361.7 Ų61.71%0.01330%0.303CS..Hα-helixtrans-63.9-44.7175.3-83.7-70.5000112L255 N256 H257 L261 L262 L263 W346 H523 V524 I527L255-F259 HydrophobicContact CD1-CD2 3.46Å; L255-F259 VanDerWaalsContact CD1-CD2 3.46Å; L255-F259 HydrophobicContact CD1-CE2 3.16Å; L255-F259 HydrophobicContact CD1-CZ 4.25Å; L255-F259 HydrophobicContact CD2-CE2 4.2Å; L255-F259 HydrophobicContact CG-CD2 3.67Å; L255-F259 HydrophobicContact CG-CE2 3.62Å; L255-F259 VanDerWaalsContact O-CD2 3.28Å; L255-F259 WeakPolarHBondContact O-CD2 3.47Å; L255-F259 PolarHBondContact O-N 2.91Å; N256-F259 PolarHBondContact O-N 2.91Å; H257-F259 VanDerWaalsContact C-N 3.32Å; H257-F259 PolarHBondContact O-N 3.16Å; F259-L261 VanDerWaalsContact C-N 3.3Å; F259-L261 PolarHBondContact O-N 3.43Å; F259-L262 HydrophobicContact CD1-CD1 4.26Å; F259-L262 CarbonylContact O-C 3.41Å; F259-L262 WeakPolarHBondContact O-CA 3.46Å; F259-L262 WeakPolarHBondContact O-CB 3.4Å; F259-L262 PolarHBondContact O-N 3.4Å; F259-L263 VanDerWaalsContact O-CG 3.31Å; F259-L263 WeakPolarHBondContact O-CG 3.43Å; F259-L263 PolarHBondContact O-N 2.83Å; F259-W346 AromaticContact CE1-CH2 3.97Å; F259-W346 HydrophobicContact CE1-CH2 3.97Å; F259-W346 HydrophobicContact CE1-CZ3 4.03Å; F259-W346 HydrophobicContact CZ-CH2 4.48Å; F259-W346 HydrophobicContact CZ-CZ3 4.36Å; F259-H523 HydrophobicContact CB-CB 4.33Å; F259-H523 VanDerWaalsContact CB-CD2 3.47Å; F259-H523 WeakPolarHBondContact CB-CD2 3.47Å; F259-H523 HydrophobicContact CD1-CB 3.65Å; F259-H523 HydrophobicContact CD2-CB 3.39Å; F259-H523 AromaticContact CD2-CD2 3.61Å; F259-H523 AromaticContact CD2-CG 3.4Å; F259-H523 HydrophobicContact CE1-CB 3.7Å; F259-H523 HydrophobicContact CE2-CB 3.37Å; F259-H523 AromaticContact CE2-CG 3.79Å; F259-H523 HydrophobicContact CG-CB 3.55Å; F259-H523 AromaticContact CG-CD2 3.61Å; F259-H523 AromaticContact CG-CG 3.71Å; F259-H523 HydrophobicContact CZ-CB 3.58Å; F259-V524 HydrophobicContact CZ-CG2 4.34Å; F259-I527 HydrophobicContact CD1-CD1 3.35Å; F259-I527 HydrophobicContact CD1-CG1 3.82Å; F259-I527 HydrophobicContact CE1-CD1 3.42Å; F259-I527 VanDerWaalsContact CE1-CD1 3.42Å; F259-I527 HydrophobicContact CE1-CG1 4.16Å
260Q71.5Confident65.3Low69 Ų6966.6 Ų66.632%0.32232%0.319SS..Hα-helixtrans-59.7-39.3175.5-71.8-62.6-26.500112.2N256 H257 L262 L263 N264N256-Q260 WeakPolarHBondContact O-CB 3.44Å; N256-Q260 VanDerWaalsContact O-CG 3.24Å; N256-Q260 WeakPolarHBondContact O-CG 3.12Å; N256-Q260 PolarHBondContact O-N 2.69Å; H257-Q260 PolarHBondContact O-N 3.42Å; Q260-L262 VanDerWaalsContact C-N 3.34Å; Q260-L262 PolarHBondContact O-N 3.46Å; Q260-L263 PolarHBondContact O-N 3.25Å; Q260-N264 VanDerWaalsContact O-CB 3.31Å; Q260-N264 WeakPolarHBondContact O-CB 3.49Å; Q260-N264 PolarHBondContact O-N 3.27Å; Q260-N264 PolarHBondContact O-ND2 2.97Å; Q260-N264 VanDerWaalsContact O-ND2 3.17Å
261L69Low63.3Low15 Ų1570.1 Ų70.18%0.07934%0.343CS..Hα-helixtrans-63.2-40173.1-70.9175000112.1E214 H257 C258 F259 N264 R265E214-L261 HydrophobicContact CB-CD1 4.32Å; E214-L261 HydrophobicContact CG-CD1 4.33Å; E214-L261 HydrophobicContact CG-CD2 4.12Å; H257-L261 WeakPolarHBondContact O-CG 3.43Å; H257-L261 PolarHBondContact O-N 2.86Å; C258-L261 PolarHBondContact O-N 2.73Å; F259-L261 VanDerWaalsContact C-N 3.3Å; F259-L261 PolarHBondContact O-N 3.43Å; L261-N264 PolarHBondContact O-N 3Å; L261-R265 WeakPolarHBondContact O-CB 3.26Å; L261-R265 PolarHBondContact O-N 3.47Å
262L66.9Low61.5Low39 Ų3972.3 Ų72.320%0.20435%0.352CS..Hα-helixtrans-64.7-38173.4-69.3168.3000112C258 F259 Q260 Y272 I275 W346 I527C258-L262 WeakPolarHBondContact O-CG 3.23Å; C258-L262 PolarHBondContact O-N 3.37Å; F259-L262 HydrophobicContact CD1-CD1 4.26Å; F259-L262 CarbonylContact O-C 3.41Å; F259-L262 WeakPolarHBondContact O-CA 3.46Å; F259-L262 WeakPolarHBondContact O-CB 3.4Å; F259-L262 PolarHBondContact O-N 3.4Å; Q260-L262 VanDerWaalsContact C-N 3.34Å; Q260-L262 PolarHBondContact O-N 3.46Å; L262-Y272 HydrophobicContact CD2-CD2 4.31Å; L262-I275 HydrophobicContact CD1-CG2 4.31Å; L262-W346 HydrophobicContact CD1-CH2 4.12Å; L262-W346 HydrophobicContact CD1-CZ2 3.82Å; L262-I527 HydrophobicContact CB-CD1 4.26Å; L262-I527 HydrophobicContact CD1-CD1 4.05Å
263L66Low60.5Low17 Ų1781 Ų819%0.08938%0.384CS..Hα-helixtrans-71-34.6175.6-60.4-176.9000112.1F259 Q260 R266 I527F259-L263 VanDerWaalsContact O-CG 3.31Å; F259-L263 WeakPolarHBondContact O-CG 3.43Å; F259-L263 PolarHBondContact O-N 2.83Å; Q260-L263 PolarHBondContact O-N 3.25Å; L263-R266 VanDerWaalsContact CB-NH2 3.27Å; L263-R266 WeakPolarHBondContact O-CD 3.35Å; L263-R266 WeakPolarHBondContact O-CG 3.39Å; L263-R266 PolarHBondContact O-NE 3.26Å; L263-I527 HydrophobicContact CD2-CB 4.13Å; L263-I527 HydrophobicContact CD2-CG1 3.5Å
264N65.5Low59.8Low122 Ų12277.9 Ų77.965%0.65237%0.371SS*.Hα-helixtrans-82.1-20.9-174.9-73-27.5000114.1Q260 L261Q260-N264 VanDerWaalsContact O-CB 3.31Å; Q260-N264 WeakPolarHBondContact O-CB 3.49Å; Q260-N264 PolarHBondContact O-N 3.27Å; Q260-N264 PolarHBondContact O-ND2 2.97Å; Q260-N264 VanDerWaalsContact O-ND2 3.17Å; L261-N264 PolarHBondContact O-N 3Å
265R58.3Low59.3Low111 Ų11177.9 Ų77.942%0.41937%0.371SS..THydrogen-bonded Turntrans-111.333.7-172-66-173168.1-169.5-9.5113.9E214 L261 F267 Y272E214-R265 VanDerWaalsContact CD-CZ 3.43Å; E214-R265 IonicContact OE1-CZ 3.98Å; E214-R265 VanDerWaalsContact OE1-CZ 3.3Å; E214-R265 IonicContact OE1-NE 2.85Å; E214-R265 IonicContact OE1-NH1 3.27Å; E214-R265 IonicContact OE1-NH2 3.88Å; E214-R265 PolarHBondContact OE1-NH2 2.96Å; E214-R265 IonicContact OE2-CZ 3.9Å; E214-R265 IonicContact OE2-NH1 3.01Å; E214-R265 PolarHBondContact OE2-NH1 3.47Å; E214-R265 IonicContact OE2-NH2 2.99Å; E214-R265 PolarHBondContact OE2-NH2 3.28Å; L261-R265 WeakPolarHBondContact O-CB 3.26Å; L261-R265 PolarHBondContact O-N 3.47Å; R265-F267 PolarHBondContact O-N 3.25Å; R265-Y272 PolarHBondContact NH1-OH 3.49Å
266R52.5Low59.1Low69 Ų6980.4 Ų80.426%0.2638%0.384SS..  trans-63.922.7-170.8-74.6175.4-174.7161.76.9117.5L263 D530 E534L263-R266 VanDerWaalsContact CB-NH2 3.27Å; L263-R266 WeakPolarHBondContact O-CD 3.35Å; L263-R266 WeakPolarHBondContact O-CG 3.39Å; L263-R266 PolarHBondContact O-NE 3.26Å; R266-D530 VanDerWaalsContact CZ-CB 3.46Å; R266-D530 IonicContact CZ-OD2 3.31Å; R266-D530 IonicContact NH1-OD2 2.67Å; R266-D530 VanDerWaalsContact NH2-CG 3.35Å; R266-D530 IonicContact NH2-OD2 2.7Å; R266-D530 PolarHBondContact NH2-OD2 3.08Å; R266-E534 WeakPolarHBondContact CD-OE1 3.22Å; R266-E534 VanDerWaalsContact CD-OE2 3.3Å; R266-E534 WeakPolarHBondContact CD-OE2 3.31Å; R266-E534 IonicContact CZ-OE1 2.71Å; R266-E534 IonicContact NE-OE1 3.74Å; R266-E534 IonicContact NH1-OE1 3.5Å; R266-E534 PolarHBondContact NH1-OE1 3.14Å
267F35.7Very low59.4Low189 Ų18978.1 Ų78.183%0.82937%0.372SS*.SBendtrans-97.9134.4167.7-74.1-82.9000111.3R265 G269R265-F267 PolarHBondContact O-N 3.25Å; F267-G269 PolarHBondContact O-N 3.34Å
268K44Very low59.8Low186 Ų18678.3 Ų78.381%0.80938%0.376SS*.THydrogen-bonded Turntrans-56.1131.5176.3-70.4-176.8174.1-169.20110
269G38.1Very low60.2Low72 Ų7278.2 Ų78.274%0.74238%0.375SS*.THydrogen-bonded Turntrans136.7-18.4171.300000115.8F267F267-G269 PolarHBondContact O-N 3.34Å
270Y34.7Very low60.7Low199 Ų19978.1 Ų78.178%0.7837%0.374SS*.  trans-102.695.9175.2-75.9-86.8000110.9Y272Y270-Y272 PolarHBondContact O-N 3.11Å
271V39Very low61.4Low123 Ų12375.2 Ų75.275%0.74536%0.361SS*.  trans-68.896.3164.4-177.40000106.4R273V271-R273 VanDerWaalsContact C-N 3.29Å; V271-R273 HydrophobicContact CG1-CG 4.4Å; V271-R273 PolarHBondContact O-N 3.22Å
272Y44.5Very low62.3Low45 Ų4575.1 Ų75.118%0.17636%0.362CS..  trans-57.5106.9156-91.2-82.2000105.1L262 R265 Y270 D274L262-Y272 HydrophobicContact CD2-CD2 4.31Å; R265-Y272 PolarHBondContact NH1-OH 3.49Å; Y270-Y272 PolarHBondContact O-N 3.11Å; Y272-D274 PolarHBondContact O-N 3.48Å
273R52Low63.2Low195 Ų19573.5 Ų73.574%0.73635%0.353SS*.SBendtrans-61.4-18.5-173.9-74.8-173.3178.4-163.8-0.2111.6V271V271-R273 VanDerWaalsContact C-N 3.29Å; V271-R273 HydrophobicContact CG1-CG 4.4Å; V271-R273 PolarHBondContact O-N 3.22Å
274D62.5Low64.1Low47 Ų4772.7 Ų72.725%0.25135%0.349SS..SBendtrans-112.7-30.5-162.8-43.6-38000114.4S218 I222 Y272 T279S218-D274 PolarHBondContact OG-OD2 3.28Å; I222-D274 HydrophobicContact CD1-CB 3.85Å; Y272-D274 PolarHBondContact O-N 3.48Å; D274-T279 WeakPolarHBondContact O-CG2 3.49Å; D274-T279 PolarHBondContact O-OG1 2.72Å
275I71.4Confident65Low10 Ų1067 Ų675%0.05132%0.319CS..  trans-119.697.4178.5-56.8175.7000110.3F221 C258 L262 I280F221-I275 HydrophobicContact CD1-CD1 3.64Å; F221-I275 HydrophobicContact CD1-CG1 4.29Å; F221-I275 HydrophobicContact CE1-CD1 4.32Å; F221-I275 HydrophobicContact CG-CD1 4.4Å; C258-I275 HydrophobicContact CB-CD1 3.5Å; C258-I275 WeakPolarHBondContact SG-CD1 3.49Å; L262-I275 HydrophobicContact CD1-CG2 4.31Å; I275-I280 HydrophobicContact CG2-CD1 3.98Å; I275-I280 HydrophobicContact CG2-CG1 4.21Å
276N75.3Confident66.3Low54 Ų5462 Ų6229%0.28930%0.3SS..SBendtrans-124.9178.817366.560.4000110.6N278 T279 I280N276-N278 VanDerWaalsContact C-N 3.28Å; N276-N278 PolarHBondContact O-N 2.9Å; N276-N278 WeakPolarHBondContact OD1-CA 3.38Å; N276-N278 VanDerWaalsContact OD1-CB 3.26Å; N276-N278 WeakPolarHBondContact OD1-CB 3.38Å; N276-N278 PolarHBondContact OD1-N 2.99Å; N276-T279 PolarHBondContact N-OG1 2.91Å; N276-T279 PolarHBondContact ND2-OG1 3.48Å; N276-T279 VanDerWaalsContact O-CB 3.28Å; N276-T279 WeakPolarHBondContact O-CB 3.4Å; N276-T279 PolarHBondContact O-N 3.12Å; N276-T279 VanDerWaalsContact O-N 3.1Å; N276-T279 PolarHBondContact OD1-N 3.49Å; N276-T279 VanDerWaalsContact OD1-N 3.14Å; N276-T279 PolarHBondContact OD1-OG1 3.33Å; N276-I280 PolarHBondContact O-N 3.06Å
277S79.4Confident67.8Low4 Ų459.1 Ų59.13%0.02829%0.29CS..Hα-helixtrans-62.7-27.6-178.649.50000114.5I281 S345 K348S277-I281 WeakPolarHBondContact O-CB 3.37Å; S277-I281 WeakPolarHBondContact O-CD1 3.44Å; S277-I281 VanDerWaalsContact O-CG1 3.27Å; S277-I281 WeakPolarHBondContact O-CG1 3.19Å; S277-I281 PolarHBondContact O-N 2.64Å; S277-S345 WeakPolarHBondContact CB-O 3.42Å; S277-S345 WeakPolarHBondContact CB-OG 3.25Å; S277-S345 WeakPolarHBondContact OG-CB 3.18Å; S277-S345 PolarHBondContact OG-O 3.43Å; S277-S345 PolarHBondContact OG-OG 3.42Å; S277-K348 WeakPolarHBondContact OG-CE 3.16Å; S277-K348 PolarHBondContact OG-NZ 3.41Å
278N82.8Confident70.1Confident71 Ų7150.1 Ų50.138%0.3825%0.25SS..Hα-helixtrans-72.7-38.6172.1-64.4-34.5000111.6N276 I280 I281 S282 K348N276-N278 VanDerWaalsContact C-N 3.28Å; N276-N278 PolarHBondContact O-N 2.9Å; N276-N278 WeakPolarHBondContact OD1-CA 3.38Å; N276-N278 VanDerWaalsContact OD1-CB 3.26Å; N276-N278 WeakPolarHBondContact OD1-CB 3.38Å; N276-N278 PolarHBondContact OD1-N 2.99Å; N278-I280 VanDerWaalsContact C-N 3.32Å; N278-I280 PolarHBondContact O-N 3.28Å; N278-I281 PolarHBondContact O-N 3.29Å; N278-S282 WeakPolarHBondContact O-CB 3.1Å; N278-S282 PolarHBondContact O-N 3.21Å; N278-S282 PolarHBondContact O-OG 3.23Å; N278-K348 PolarHBondContact OD1-NZ 3Å
279T82.2Confident72Confident3 Ų341.7 Ų41.72%0.01821%0.214CC..Hα-helixtrans-58.3-47.2174.1-44.40000110.5L164 D274 N276 S282 L283L164-T279 HydrophobicContact CB-CG2 4.25Å; L164-T279 HydrophobicContact CD1-CG2 3.52Å; D274-T279 WeakPolarHBondContact O-CG2 3.49Å; D274-T279 PolarHBondContact O-OG1 2.72Å; N276-T279 PolarHBondContact N-OG1 2.91Å; N276-T279 PolarHBondContact ND2-OG1 3.48Å; N276-T279 VanDerWaalsContact O-CB 3.28Å; N276-T279 WeakPolarHBondContact O-CB 3.4Å; N276-T279 PolarHBondContact O-N 3.12Å; N276-T279 VanDerWaalsContact O-N 3.1Å; N276-T279 PolarHBondContact OD1-N 3.49Å; N276-T279 VanDerWaalsContact OD1-N 3.14Å; N276-T279 PolarHBondContact OD1-OG1 3.33Å; T279-S282 WeakPolarHBondContact O-CB 3.08Å; T279-S282 PolarHBondContact O-N 3.33Å; T279-L283 PolarHBondContact O-N 3Å
280I83.8Confident74Confident0 Ų038.4 Ų38.40%018%0.179CC..Hα-helixtrans-70-38.7179-60.4-57.9000111.8F221 I275 N276 N278 S282 L283 V284 W346 V349 V520F221-I280 HydrophobicContact CE1-CD1 4.45Å; I275-I280 HydrophobicContact CG2-CD1 3.98Å; I275-I280 HydrophobicContact CG2-CG1 4.21Å; N276-I280 PolarHBondContact O-N 3.06Å; N278-I280 VanDerWaalsContact C-N 3.32Å; N278-I280 PolarHBondContact O-N 3.28Å; I280-S282 PolarHBondContact O-N 3.37Å; I280-L283 HydrophobicContact CD1-CD2 4.34Å; I280-L283 PolarHBondContact O-N 3.37Å; I280-V284 HydrophobicContact CG2-CG2 4.13Å; I280-V284 WeakPolarHBondContact O-CB 3.27Å; I280-V284 WeakPolarHBondContact O-CG2 3.39Å; I280-V284 PolarHBondContact O-N 2.88Å; I280-W346 HydrophobicContact CB-CZ3 4.06Å; I280-W346 HydrophobicContact CG1-CH2 3.75Å; I280-W346 HydrophobicContact CG1-CZ3 3.68Å; I280-W346 HydrophobicContact CG2-CZ3 4.27Å; I280-V349 HydrophobicContact CB-CG1 4.4Å; I280-V349 HydrophobicContact CG2-CG1 3.63Å; I280-V520 HydrophobicContact CG2-CG1 3.81Å
281I85.3Confident76Confident8 Ų829.4 Ų29.44%0.04114%0.144CC..Hα-helixtrans-57.2-41.7170.7-75.7165000110.7S277 N278 V284 S285 K348 V349 V352 E421 V425S277-I281 WeakPolarHBondContact O-CB 3.37Å; S277-I281 WeakPolarHBondContact O-CD1 3.44Å; S277-I281 VanDerWaalsContact O-CG1 3.27Å; S277-I281 WeakPolarHBondContact O-CG1 3.19Å; S277-I281 PolarHBondContact O-N 2.64Å; N278-I281 PolarHBondContact O-N 3.29Å; I281-V284 PolarHBondContact O-N 3.01Å; I281-S285 VanDerWaalsContact O-CB 3.27Å; I281-S285 WeakPolarHBondContact O-CB 3.4Å; I281-S285 PolarHBondContact O-N 3.03Å; I281-S285 PolarHBondContact O-OG 3.17Å; I281-K348 HydrophobicContact CD1-CB 4.28Å; I281-K348 HydrophobicContact CD1-CD 3.68Å; I281-K348 HydrophobicContact CD1-CG 3.9Å; I281-V349 HydrophobicContact CD1-CG2 4.39Å; I281-V349 HydrophobicContact CG1-CB 4.46Å; I281-V349 HydrophobicContact CG1-CG2 4.08Å; I281-V352 HydrophobicContact CD1-CG2 4.5Å; I281-V352 HydrophobicContact CG1-CG2 4.42Å; I281-E421 HydrophobicContact CD1-CB 4.15Å; I281-V425 HydrophobicContact CG2-CG1 4.04Å
282S88.3Confident77.8Confident14 Ų1425 Ų2510%0.09812%0.116CC..Hα-helixtrans-68.2-40.7180-58.20000112.2E165 N278 T279 I280 S285 I286E165-S282 WeakPolarHBondContact CG-OG 3.39Å; N278-S282 WeakPolarHBondContact O-CB 3.1Å; N278-S282 PolarHBondContact O-N 3.21Å; N278-S282 PolarHBondContact O-OG 3.23Å; T279-S282 WeakPolarHBondContact O-CB 3.08Å; T279-S282 PolarHBondContact O-N 3.33Å; I280-S282 PolarHBondContact O-N 3.37Å; S282-S285 WeakPolarHBondContact O-CB 3.31Å; S282-S285 PolarHBondContact O-N 2.78Å; S282-I286 VanDerWaalsContact O-CG1 3.27Å; S282-I286 WeakPolarHBondContact O-CG1 3.32Å; S282-I286 PolarHBondContact O-N 3.45Å
283L86.7Confident79.5Confident4 Ų423.5 Ų23.52%0.02111%0.111CC..Hα-helixtrans-60.3-50172.7176.469.3000111.6L164 F221 T279 I280 S285 I286 Q287 V520L164-L283 HydrophobicContact CD2-CD1 4.17Å; F221-L283 HydrophobicContact CE1-CD2 4.29Å; F221-L283 HydrophobicContact CZ-CD2 3.57Å; T279-L283 PolarHBondContact O-N 3Å; I280-L283 HydrophobicContact CD1-CD2 4.34Å; I280-L283 PolarHBondContact O-N 3.37Å; L283-S285 VanDerWaalsContact C-N 3.27Å; L283-S285 PolarHBondContact O-N 2.87Å; L283-I286 WeakPolarHBondContact O-CB 3.2Å; L283-I286 PolarHBondContact O-N 3.36Å; L283-Q287 WeakPolarHBondContact O-CG 3.46Å; L283-Q287 PolarHBondContact O-N 2.92Å; L283-V520 HydrophobicContact CD2-CG2 4.43Å
284V83.4Confident80.5Confident1 Ų114.5 Ų14.51%0.0068%0.077CC..Hα-helixtrans-60.8-39.7178.9169.80000110.4I280 I281 Q287 M288 V352 I353 V520I280-V284 HydrophobicContact CG2-CG2 4.13Å; I280-V284 WeakPolarHBondContact O-CB 3.27Å; I280-V284 WeakPolarHBondContact O-CG2 3.39Å; I280-V284 PolarHBondContact O-N 2.88Å; I281-V284 PolarHBondContact O-N 3.01Å; V284-Q287 WeakPolarHBondContact O-CB 3.12Å; V284-Q287 PolarHBondContact O-N 3.12Å; V284-M288 HydrophobicContact CG1-CE 3.17Å; V284-M288 HydrophobicContact CG1-SD 3.95Å; V284-M288 WeakPolarHBondContact O-CG 3.35Å; V284-M288 PolarHBondContact O-N 3.02Å; V284-V352 HydrophobicContact CG1-CG1 4.49Å; V284-I353 HydrophobicContact CG1-CG1 4.23Å; V284-V520 HydrophobicContact CG2-CG1 3.75Å
285S86.2Confident81Confident2 Ų216.3 Ų16.31%0.0148%0.084CC..Hα-helixtrans-62.6-44.8174.6-60.30000112.4I281 S282 L283 Q287 M288 E289 V425 I428I281-S285 VanDerWaalsContact O-CB 3.27Å; I281-S285 WeakPolarHBondContact O-CB 3.4Å; I281-S285 PolarHBondContact O-N 3.03Å; I281-S285 PolarHBondContact O-OG 3.17Å; S282-S285 WeakPolarHBondContact O-CB 3.31Å; S282-S285 PolarHBondContact O-N 2.78Å; L283-S285 VanDerWaalsContact C-N 3.27Å; L283-S285 PolarHBondContact O-N 2.87Å; S285-Q287 VanDerWaalsContact C-N 3.31Å; S285-Q287 PolarHBondContact O-N 3.2Å; S285-M288 PolarHBondContact O-N 2.81Å; S285-E289 PolarHBondContact O-N 2.89Å; S285-V425 WeakPolarHBondContact OG-CG1 3.28Å; S285-I428 VanDerWaalsContact CB-CD1 3.44Å
286I85.5Confident81.2Confident5 Ų521.7 Ų21.73%0.02611%0.109CC..Hα-helixtrans-60.2-44.5174.9-70.2162.1000110.4L164 A167 C168 L171 A229 S282 L283 E289 L290L164-I286 HydrophobicContact CD2-CD1 4.23Å; L164-I286 WeakPolarHBondContact O-CD1 3.27Å; A167-I286 HydrophobicContact CB-CD1 3.85Å; C168-I286 HydrophobicContact CB-CD1 4.08Å; C168-I286 HydrophobicContact CB-CG1 3.92Å; L171-I286 HydrophobicContact CD2-CB 4.3Å; L171-I286 HydrophobicContact CD2-CG1 4.32Å; L171-I286 HydrophobicContact CD2-CG2 4.04Å; A229-I286 HydrophobicContact CB-CG2 4.04Å; S282-I286 VanDerWaalsContact O-CG1 3.27Å; S282-I286 WeakPolarHBondContact O-CG1 3.32Å; S282-I286 PolarHBondContact O-N 3.45Å; L283-I286 WeakPolarHBondContact O-CB 3.2Å; L283-I286 PolarHBondContact O-N 3.36Å; I286-E289 PolarHBondContact O-N 2.78Å; I286-L290 HydrophobicContact CG2-CD1 3.67Å; I286-L290 HydrophobicContact CG2-CG 4.26Å; I286-L290 WeakPolarHBondContact O-CB 3.43Å; I286-L290 WeakPolarHBondContact O-CG 3.48Å; I286-L290 PolarHBondContact O-N 2.87Å
287Q83.6Confident81Confident9 Ų924 Ų244%0.04212%0.117CC..Hα-helixtrans-61.8-46.3179-74170.1-12.800111.6L283 V284 S285 L290 I291 L515 I517L283-Q287 WeakPolarHBondContact O-CG 3.46Å; L283-Q287 PolarHBondContact O-N 2.92Å; V284-Q287 WeakPolarHBondContact O-CB 3.12Å; V284-Q287 PolarHBondContact O-N 3.12Å; S285-Q287 VanDerWaalsContact C-N 3.31Å; S285-Q287 PolarHBondContact O-N 3.2Å; Q287-L290 PolarHBondContact O-N 2.92Å; Q287-I291 VanDerWaalsContact O-CG1 3.31Å; Q287-I291 WeakPolarHBondContact O-CG1 2.94Å; Q287-I291 PolarHBondContact O-N 3.39Å; Q287-L515 HydrophobicContact CB-CD2 3.63Å; Q287-L515 HydrophobicContact CG-CD2 3.85Å; Q287-I517 HydrophobicContact CB-CD1 3.96Å; Q287-I517 HydrophobicContact CB-CG1 3.85Å; Q287-I517 HydrophobicContact CG-CG1 4.47Å
288M83.6Confident80.2Confident0 Ų027 Ų270%015%0.148CC..Hα-helixtrans-59.1-50.8176.7-69.2167.5179.700111.9V284 S285 L290 I291 E292 V352 W356 I428 L429 I517V284-M288 HydrophobicContact CG1-CE 3.17Å; V284-M288 HydrophobicContact CG1-SD 3.95Å; V284-M288 WeakPolarHBondContact O-CG 3.35Å; V284-M288 PolarHBondContact O-N 3.02Å; S285-M288 PolarHBondContact O-N 2.81Å; M288-L290 VanDerWaalsContact C-N 3.33Å; M288-L290 PolarHBondContact O-N 3.21Å; M288-I291 WeakPolarHBondContact O-CB 3.31Å; M288-I291 PolarHBondContact O-N 3.11Å; M288-E292 PolarHBondContact O-N 3.46Å; M288-E292 VanDerWaalsContact O-N 3.09Å; M288-V352 HydrophobicContact CE-CG1 4.42Å; M288-W356 HydrophobicContact CE-CB 3.33Å; M288-W356 HydrophobicContact CE-CD2 3.86Å; M288-W356 HydrophobicContact CE-CE3 4.34Å; M288-W356 HydrophobicContact CE-CG 3.41Å; M288-W356 VanDerWaalsContact CE-CG 3.41Å; M288-W356 HydrophobicContact CG-CD2 4.19Å; M288-W356 HydrophobicContact CG-CG 3.99Å; M288-W356 HydrophobicContact SD-CB 4.06Å; M288-W356 HydrophobicContact SD-CG 3.89Å; M288-I428 HydrophobicContact CB-CG2 3.73Å; M288-I428 HydrophobicContact SD-CG2 4.48Å; M288-L429 HydrophobicContact SD-CD2 3.96Å; M288-I517 HydrophobicContact CG-CD1 4.45Å
289E83.3Confident79.1Confident10 Ų1025.3 Ų25.35%0.04714%0.142CC..Hα-helixtrans-62.2-38.2178.7-81.1-69.9157.600112.8L171 R175 S285 I286 E292 L293 I428L171-E289 HydrophobicContact CD2-CB 3.7Å; L171-E289 HydrophobicContact CG-CB 4.17Å; R175-E289 IonicContact NE-OE2 2.76Å; R175-E289 PolarHBondContact NE-OE2 3.47Å; S285-E289 PolarHBondContact O-N 2.89Å; I286-E289 PolarHBondContact O-N 2.78Å; E289-E292 PolarHBondContact O-N 3.43Å; E289-L293 WeakPolarHBondContact O-CB 3.34Å; E289-L293 PolarHBondContact O-N 2.61Å; E289-I428 HydrophobicContact CG-CD1 3.93Å; E289-I428 HydrophobicContact CG-CG1 3.97Å; E289-I428 HydrophobicContact CG-CG2 4.15Å; E289-I428 WeakPolarHBondContact OE1-CG1 3.19Å
290L81Confident77.6Confident3 Ų335.3 Ų35.32%0.01618%0.179CC..Hα-helixtrans-68-37176.2-72.9172.7000112L171 A229 L232 Y233 I286 Q287 M288 L293 L294L171-L290 HydrophobicContact CD2-CD2 4.47Å; L171-L290 HydrophobicContact CD2-CG 4.23Å; A229-L290 HydrophobicContact CB-CD1 3.88Å; L232-L290 HydrophobicContact CB-CD1 4.23Å; L232-L290 HydrophobicContact CB-CD2 4.45Å; L232-L290 HydrophobicContact CD1-CD1 4.16Å; Y233-L290 HydrophobicContact CD2-CD2 4.2Å; I286-L290 HydrophobicContact CG2-CD1 3.67Å; I286-L290 HydrophobicContact CG2-CG 4.26Å; I286-L290 WeakPolarHBondContact O-CB 3.43Å; I286-L290 WeakPolarHBondContact O-CG 3.48Å; I286-L290 PolarHBondContact O-N 2.87Å; Q287-L290 PolarHBondContact O-N 2.92Å; M288-L290 VanDerWaalsContact C-N 3.33Å; M288-L290 PolarHBondContact O-N 3.21Å; L290-L293 HydrophobicContact CD2-CD2 4.33Å; L290-L293 PolarHBondContact O-N 2.72Å; L290-L294 WeakPolarHBondContact O-CB 3.39Å; L290-L294 WeakPolarHBondContact O-CG 3.49Å; L290-L294 PolarHBondContact O-N 3.35Å
291I76.2Confident76.3Confident9 Ų936.5 Ų36.55%0.04618%0.184CC..Hα-helixtrans-59.5-51173.3-69.9166.2000109.7Q287 M288 L293 L294 Q295 W356 L515 I517Q287-I291 VanDerWaalsContact O-CG1 3.31Å; Q287-I291 WeakPolarHBondContact O-CG1 2.94Å; Q287-I291 PolarHBondContact O-N 3.39Å; M288-I291 WeakPolarHBondContact O-CB 3.31Å; M288-I291 PolarHBondContact O-N 3.11Å; I291-L293 PolarHBondContact O-N 3.47Å; I291-L294 PolarHBondContact O-N 2.91Å; I291-Q295 HydrophobicContact CG2-CG 4.37Å; I291-Q295 VanDerWaalsContact O-CG 3.31Å; I291-Q295 WeakPolarHBondContact O-CG 3.48Å; I291-Q295 PolarHBondContact O-N 3.41Å; I291-W356 HydrophobicContact CD1-CH2 4.13Å; I291-W356 HydrophobicContact CD1-CZ2 3.8Å; I291-L515 HydrophobicContact CD1-CD2 3.85Å; I291-L515 HydrophobicContact CG1-CD1 4.39Å; I291-L515 HydrophobicContact CG1-CD2 3.77Å; I291-I517 HydrophobicContact CD1-CD1 3.45Å; I291-I517 VanDerWaalsContact CD1-CD1 3.45Å
292E77.7Confident74.6Confident30 Ų3037 Ų3714%0.1419%0.189CC..Hα-helixtrans-58.7-46.3178.5-70-170.6-175.800111.7M288 E289 L294 Q295 E296M288-E292 PolarHBondContact O-N 3.46Å; M288-E292 VanDerWaalsContact O-N 3.09Å; E289-E292 PolarHBondContact O-N 3.43Å; E292-L294 VanDerWaalsContact C-N 3.33Å; E292-L294 PolarHBondContact O-N 2.88Å; E292-Q295 PolarHBondContact O-N 3.45Å; E292-E296 WeakPolarHBondContact O-CG 3.26Å; E292-E296 PolarHBondContact O-N 3.31Å
293L78.5Confident72.5Confident15 Ų1544.3 Ų44.38%0.07922%0.219CC..Hα-helixtrans-58.3-43.1177.4-173.887.6000112.2Y233 E289 L290 I291 K297Y233-L293 HydrophobicContact CD2-CD2 3.8Å; Y233-L293 HydrophobicContact CE2-CD2 4.25Å; E289-L293 WeakPolarHBondContact O-CB 3.34Å; E289-L293 PolarHBondContact O-N 2.61Å; L290-L293 HydrophobicContact CD2-CD2 4.33Å; L290-L293 PolarHBondContact O-N 2.72Å; I291-L293 PolarHBondContact O-N 3.47Å; L293-K297 WeakPolarHBondContact O-CG 3.31Å; L293-K297 PolarHBondContact O-N 3.05Å; L293-K297 VanDerWaalsContact O-N 3.09Å
294L73.8Confident70.5Confident5 Ų545 Ų453%0.02622%0.223CC..Hα-helixtrans-69.3-37.9179.9-70.8173.6000111.6L232 L290 I291 E292 K297 G298 S299 K301 A302L232-L294 HydrophobicContact CB-CD1 4.43Å; L232-L294 HydrophobicContact CD2-CD1 4.1Å; L290-L294 WeakPolarHBondContact O-CB 3.39Å; L290-L294 WeakPolarHBondContact O-CG 3.49Å; L290-L294 PolarHBondContact O-N 3.35Å; I291-L294 PolarHBondContact O-N 2.91Å; E292-L294 VanDerWaalsContact C-N 3.33Å; E292-L294 PolarHBondContact O-N 2.88Å; L294-K297 PolarHBondContact O-N 3.47Å; L294-G298 PolarHBondContact O-N 3.46Å; L294-S299 PolarHBondContact O-N 2.86Å; L294-K301 HydrophobicContact CD1-CB 3.91Å; L294-K301 HydrophobicContact CD2-CB 3.91Å; L294-K301 HydrophobicContact CD2-CD 4.12Å; L294-K301 HydrophobicContact CG-CB 4.39Å; L294-A302 HydrophobicContact CB-CB 4.11Å
295Q72.6Confident68.3Low85 Ų8545.7 Ų45.740%0.39723%0.228SC..Hα-helixtrans-63.4-46.6174.4-73175.3-7.200111.2I291 E292 K297 G298 A302I291-Q295 HydrophobicContact CG2-CG 4.37Å; I291-Q295 VanDerWaalsContact O-CG 3.31Å; I291-Q295 WeakPolarHBondContact O-CG 3.48Å; I291-Q295 PolarHBondContact O-N 3.41Å; E292-Q295 PolarHBondContact O-N 3.45Å; Q295-K297 VanDerWaalsContact C-N 3.31Å; Q295-K297 PolarHBondContact O-N 3.34Å; Q295-G298 PolarHBondContact O-N 3.11Å; Q295-A302 HydrophobicContact CB-CB 4.41Å; Q295-A302 HydrophobicContact CG-CB 3.83Å
296E75.7Confident65.8Low124 Ų12449.6 Ų49.658%0.57925%0.245SC*.Hα-helixtrans-60.1-38.8176.3-75.5176.4-175.700112.7R175 E292 G298R175-E296 IonicContact CZ-OE1 3.35Å; R175-E296 IonicContact CZ-OE2 3.18Å; R175-E296 IonicContact NH1-OE1 3.38Å; R175-E296 IonicContact NH1-OE2 3.16Å; R175-E296 PolarHBondContact NH1-OE2 2.96Å; R175-E296 IonicContact NH2-OE1 3.69Å; R175-E296 PolarHBondContact NH2-OE1 3.33Å; R175-E296 IonicContact NH2-OE2 2.87Å; R175-E296 PolarHBondContact NH2-OE2 3.34Å; R175-E296 VanDerWaalsContact NH2-OE2 3.07Å; E292-E296 WeakPolarHBondContact O-CG 3.26Å; E292-E296 PolarHBondContact O-N 3.31Å; E296-G298 PolarHBondContact O-N 3.43Å
297K72.3Confident63.1Low102 Ų10256.2 Ų56.244%0.44328%0.28SS..THydrogen-bonded Turntrans-72.7-5176.4-72.9-179.7179.1-175.20113.4N235 L293 L294 Q295 S299N235-K297 PolarHBondContact OD1-NZ 2.83Å; L293-K297 WeakPolarHBondContact O-CG 3.31Å; L293-K297 PolarHBondContact O-N 3.05Å; L293-K297 VanDerWaalsContact O-N 3.09Å; L294-K297 PolarHBondContact O-N 3.47Å; Q295-K297 VanDerWaalsContact C-N 3.31Å; Q295-K297 PolarHBondContact O-N 3.34Å; K297-S299 PolarHBondContact O-N 3.48Å; K297-S299 VanDerWaalsContact O-N 3.17Å
298G62.2Low60.4Low66 Ų6658 Ų5868%0.6829%0.29SS*.THydrogen-bonded Turntrans6022.1-172.600000112.9L294 Q295 E296L294-G298 PolarHBondContact O-N 3.46Å; Q295-G298 PolarHBondContact O-N 3.11Å; E296-G298 PolarHBondContact O-N 3.43Å
299S58.5Low57.9Low36 Ų3663.1 Ų63.125%0.25232%0.323SS..  trans-67.6138.3-174.3-175.50000109.6L294 K297 K301 A302L294-S299 PolarHBondContact O-N 2.86Å; K297-S299 PolarHBondContact O-N 3.48Å; K297-S299 VanDerWaalsContact O-N 3.17Å; S299-K301 PolarHBondContact O-N 3.17Å; S299-K301 VanDerWaalsContact O-N 3.1Å; S299-K301 WeakPolarHBondContact OG-CB 3.46Å; S299-K301 WeakPolarHBondContact OG-CG 3.38Å; S299-K301 PolarHBondContact OG-N 3.05Å; S299-A302 WeakPolarHBondContact O-CB 3.45Å; S299-A302 PolarHBondContact O-N 3.49Å
300R52.4Low55.2Low214 Ų21465.7 Ų65.781%0.80835%0.346SS*.G310 helixtrans-57-25.1169.5-74.6-172.8-175.7-176.33.8111.8A302 K303R300-A302 PolarHBondContact O-N 2.98Å; R300-K303 PolarHBondContact O-N 3.4Å
301K56.3Low52.6Low25 Ų2569.1 Ų69.111%0.10937%0.37CS..G310 helixtrans-55.1-20.2171-58.6-178.6179.3-178.10112.9Y231 T236 D241 L294 S299 I304Y231-K301 PolarHBondContact O-NZ 3.04Å; T236-K301 PolarHBondContact OG1-NZ 2.78Å; D241-K301 WeakPolarHBondContact OD1-CE 3.34Å; D241-K301 IonicContact OD1-NZ 3.51Å; L294-K301 HydrophobicContact CD1-CB 3.91Å; L294-K301 HydrophobicContact CD2-CB 3.91Å; L294-K301 HydrophobicContact CD2-CD 4.12Å; L294-K301 HydrophobicContact CG-CB 4.39Å; S299-K301 PolarHBondContact O-N 3.17Å; S299-K301 VanDerWaalsContact O-N 3.1Å; S299-K301 WeakPolarHBondContact OG-CB 3.46Å; S299-K301 WeakPolarHBondContact OG-CG 3.38Å; S299-K301 PolarHBondContact OG-N 3.05Å; K301-I304 WeakPolarHBondContact O-CB 3.39Å
302A48.4Very low50.3Low17 Ų1771.7 Ų71.714%0.1440%0.399CS..G310 helixtrans-79.9-23.2176.600000114.6L294 Q295 S299 R300 I304L294-A302 HydrophobicContact CB-CB 4.11Å; Q295-A302 HydrophobicContact CB-CB 4.41Å; Q295-A302 HydrophobicContact CG-CB 3.83Å; S299-A302 WeakPolarHBondContact O-CB 3.45Å; S299-A302 PolarHBondContact O-N 3.49Å; R300-A302 PolarHBondContact O-N 2.98Å; A302-I304 PolarHBondContact O-N 3.32Å
303K43.8Very low47.8Very low168 Ų16873.2 Ų73.273%0.7341%0.408SS*.G310 helixtrans-74.8-7.3176.8-80.7-174.7175.4-177.30113.2R300 S305R300-K303 PolarHBondContact O-N 3.4Å; K303-S305 PolarHBondContact O-N 3.13Å
304I45.1Very low45.5Very low18 Ų1877.1 Ų77.19%0.09243%0.428CS..G310 helixtrans-81.66.8-174.5-55.3-178.7000112.1K301 A302 D512 G513K301-I304 WeakPolarHBondContact O-CB 3.39Å; A302-I304 PolarHBondContact O-N 3.32Å; I304-D512 HydrophobicContact CG1-CB 4.25Å; I304-D512 HydrophobicContact CG2-CB 4.14Å; I304-G513 WeakPolarHBondContact CG2-O 3.26Å
305S36.6Very low43.2Very low16 Ų1681.7 Ų81.711%0.11246%0.458CS..G310 helixtrans-87.6-6.5176.273.90000113.9K303 E363K303-S305 PolarHBondContact O-N 3.13Å; S305-E363 WeakPolarHBondContact CB-OE1 3.39Å; S305-E363 VanDerWaalsContact O-OE2 3.06Å; S305-E363 PolarHBondContact OG-OE1 3.48Å
306H35.6Very low41.1Very low84 Ų8482.2 Ų82.239%0.38948%0.477SS..  trans-114.4105.2-173.5-53.9-39.8000111.1E362 E363H306-E362 WeakPolarHBondContact CE1-CG 3.29Å; H306-E363 IonicContact CE1-OE1 3.2Å; H306-E363 PolarHBondContact CE1-OE1 2.79Å; H306-E363 IonicContact ND1-OE1 3.21Å; H306-E363 PolarHBondContact ND1-OE1 2.97Å
307L28Very low38.8Very low144 Ų14485.1 Ų85.175%0.75449%0.488SS*.  trans151.288.3141.7-78159.3000111.8
308L27.5Very low36.5Very low48 Ų4884.2 Ų84.225%0.25149%0.486SS..PPolyproline II helixtrans-79.9133.2165.6-106.3169.4000110.6A366L308-A366 WeakPolarHBondContact CB-O 3.28Å
309P30.4Very low34.8Very low106 Ų10688 Ų8869%0.68850%0.496SS*.PPolyproline II helixtrans-81.2128.5158-4.722.4000110.3
310A26.4Very low33.3Very low65 Ų6590.9 Ų90.954%0.53751%0.508SS..PPolyproline II helixtrans-66.9132.117600000112.5
311S27.6Very low32.3Very low75 Ų7588.3 Ų88.352%0.52450%0.502SS..  trans-120.3106.9170.5170.80000111.4
312G27Very low31.1Very low62 Ų6293.4 Ų93.464%0.63953%0.531SS*.  trans71.599.4138.500000120.5
313N25.7Very low30.2Very low63 Ų6396.5 Ų96.534%0.33755%0.552SS.*  trans-81.4141.2163.8-74-34.5000112.5A373 D483N313-A373 VanDerWaalsContact OD1-CB 3.23Å; N313-A373 WeakPolarHBondContact OD1-CB 3.38Å; N313-D483 VanDerWaalsContact ND2-CB 3.25Å; N313-D483 WeakPolarHBondContact ND2-CB 3.19Å; N313-D483 PolarHBondContact ND2-OD2 3.06Å
314I28.7Very low29.6Very low97 Ų9794.9 Ų94.950%0.49755%0.551SS.*  trans-146.5127.9155.4-54.2179.9000109.5M490 P493I314-M490 HydrophobicContact CG2-CB 4.23Å; I314-P493 HydrophobicContact CD1-CG 3.93Å
315P27.4Very low29.3Very low101 Ų101101.3 Ų101.366%0.65659%0.586SS**  trans-108.3163.4-172.439.2-31.9000115.2
316A27Very low29.4Very low96 Ų96104.6 Ų104.679%0.79360%0.602SS**  trans-150.4146.9162.400000115
317K27.9Very low29.2Very low185 Ų185102.3 Ų102.380%0.80460%0.597SS**  trans-81.6165.2-162.2-80.4170.5175.8166.80116.7D488K317-D488 IonicContact NZ-OD1 2.96Å; K317-D488 PolarHBondContact NZ-OD1 3.41Å
318M25Very low29.5Very low83 Ų83103.3 Ų103.341%0.40960%0.595SS.*  trans-79.6175-175-66.9178.168.200115.7T476M318-T476 HydrophobicContact CE-CG2 3.18Å; M318-T476 HydrophobicContact SD-CG2 3.49Å; M318-T476 WeakPolarHBondContact SD-CG2 3.34Å
319V26.5Very low30Very low146 Ų146104.9 Ų104.989%0.88561%0.607SS**  -164.6139.31191530000111.9
320N27.1Very low30.5Very low95 Ų95101.2 Ų101.251%0.50859%0.585SS.*  trans-78.7175.8173.3-103.2-19.1000110.3
321K30.4Very low31.2Very low160 Ų16098.9 Ų98.970%0.69657%0.565SS**  cis-170.5155.81-121.7170.5-178.8177.50103.6
322N30.2Very low32.3Very low133 Ų13398.9 Ų98.971%0.71156%0.561SS**  171.8118.3122.3-87.3-12000109.9L326N322-L326 WeakPolarHBondContact O-CD1 3.43Å; N322-L326 WeakPolarHBondContact O-CD2 3.17Å
323S30.2Very low33.7Very low82 Ų8297.8 Ų97.857%0.57354%0.54SS*.  trans-87.8147172.358.30000109.1
324N31.8Very low35.4Very low134 Ų13495.1 Ų95.172%0.71753%0.526SS*.SBend-157.1-11.285.7-88-17.5000114.5
325D37.5Very low36.9Very low153 Ų15391.4 Ų91.482%0.81851%0.509SS*.THydrogen-bonded Turntrans-78.9-16.8161.4-74-43.9000112.2A327D325-A327 PolarHBondContact O-N 3.48Å; D325-A327 VanDerWaalsContact O-N 3.17Å
326L39.6Very low38.6Very low85 Ų8593.1 Ų93.145%0.44550%0.502SS..Hα-helixtrans-61.1-19.7175.9-84.179.5000113.4N322 K328 V329 A330N322-L326 WeakPolarHBondContact O-CD1 3.43Å; N322-L326 WeakPolarHBondContact O-CD2 3.17Å; L326-K328 PolarHBondContact O-N 3.35Å; L326-V329 PolarHBondContact O-N 3.49Å; L326-A330 WeakPolarHBondContact O-CA 3.24Å; L326-A330 WeakPolarHBondContact O-CB 3.43Å; L326-A330 PolarHBondContact O-N 2.86Å
327A31.5Very low40.6Very low35 Ų3590 Ų9029%0.28947%0.471SS..Hα-helixtrans-65.9-38-172.400000112.6D325 C331 R394D325-A327 PolarHBondContact O-N 3.48Å; D325-A327 VanDerWaalsContact O-N 3.17Å; A327-C331 PolarHBondContact O-N 3.02Å; A327-R394 VanDerWaalsContact C-NH1 3.26Å; A327-R394 PolarHBondContact O-NH1 3.4Å
328K34.3Very low42.8Very low166 Ų16681.2 Ų81.272%0.72243%0.432SS*.Hα-helixtrans-71.9-43.9174.7-78.5-178.8-180173.10111.6L326 C331 V332L326-K328 PolarHBondContact O-N 3.35Å; K328-C331 PolarHBondContact O-N 2.88Å; K328-V332 PolarHBondContact O-N 3.34Å; K328-V332 VanDerWaalsContact O-N 3.15Å
329V37.2Very low45Very low81 Ų8183.3 Ų83.349%0.49144%0.436SS..Hα-helixtrans-65.1-40.6177.9-174.80000110.6L326 V332 M333L326-V329 PolarHBondContact O-N 3.49Å; V329-V332 PolarHBondContact O-N 2.93Å; V329-M333 HydrophobicContact CB-CE 4.45Å; V329-M333 HydrophobicContact CG1-CE 3.78Å; V329-M333 HydrophobicContact CG1-CG 4.36Å; V329-M333 HydrophobicContact CG1-SD 3.81Å; V329-M333 WeakPolarHBondContact O-CB 3.33Å; V329-M333 WeakPolarHBondContact O-CG 3.11Å; V329-M333 PolarHBondContact O-N 3.42Å
330A41.7Very low46.9Very low29 Ų2977.4 Ų77.424%0.2440%0.402CS..Hα-helixtrans-60.6-47.8174.200000110.1L326 V332 M333 V334L326-A330 WeakPolarHBondContact O-CA 3.24Å; L326-A330 WeakPolarHBondContact O-CB 3.43Å; L326-A330 PolarHBondContact O-N 2.86Å; A330-V332 VanDerWaalsContact C-N 3.29Å; A330-V332 PolarHBondContact O-N 3.28Å; A330-M333 CarbonylContact O-C 3.53Å; A330-M333 PolarHBondContact O-N 3.21Å; A330-M333 VanDerWaalsContact O-N 3.09Å; A330-V334 WeakPolarHBondContact O-CB 3.43Å; A330-V334 WeakPolarHBondContact O-CG2 3.47Å; A330-V334 PolarHBondContact O-N 3.36Å
331C41.1Very low49.1Very low15 Ų1573 Ų7310%0.10138%0.378CS..Hα-helixtrans-57.3-41.2175.1-177.50000112.8A327 K328 S335 R394A327-C331 PolarHBondContact O-N 3.02Å; K328-C331 PolarHBondContact O-N 2.88Å; C331-S335 VanDerWaalsContact O-CB 3.24Å; C331-S335 WeakPolarHBondContact O-CB 3.45Å; C331-S335 PolarHBondContact O-N 2.67Å; C331-S335 PolarHBondContact O-OG 2.82Å; C331-R394 VanDerWaalsContact SG-CB 3.55Å; C331-R394 WeakPolarHBondContact SG-CD 3.17Å
332V51Low51.3Low75 Ų7567.5 Ų67.546%0.45536%0.355SS..Hα-helixtrans-66-42.5175.7174.10000111K328 V329 A330 S335 R336K328-V332 PolarHBondContact O-N 3.34Å; K328-V332 VanDerWaalsContact O-N 3.15Å; V329-V332 PolarHBondContact O-N 2.93Å; A330-V332 VanDerWaalsContact C-N 3.29Å; A330-V332 PolarHBondContact O-N 3.28Å; V332-S335 PolarHBondContact O-N 3.18Å; V332-R336 WeakPolarHBondContact O-CB 3.17Å; V332-R336 WeakPolarHBondContact O-CG 3.26Å; V332-R336 PolarHBondContact O-N 3.44Å
333M55.4Low53.1Low39 Ų3966.6 Ų66.619%0.19235%0.347CS..Hα-helixtrans-69.1-39.5179.8-69.4-179.3-45.800112.4V329 A330 R336 K337 R543V329-M333 HydrophobicContact CB-CE 4.45Å; V329-M333 HydrophobicContact CG1-CE 3.78Å; V329-M333 HydrophobicContact CG1-CG 4.36Å; V329-M333 HydrophobicContact CG1-SD 3.81Å; V329-M333 WeakPolarHBondContact O-CB 3.33Å; V329-M333 WeakPolarHBondContact O-CG 3.11Å; V329-M333 PolarHBondContact O-N 3.42Å; A330-M333 CarbonylContact O-C 3.53Å; A330-M333 PolarHBondContact O-N 3.21Å; A330-M333 VanDerWaalsContact O-N 3.09Å; M333-R336 CarbonylContact O-C 3.35Å; M333-R336 WeakPolarHBondContact O-CB 3.12Å; M333-R336 PolarHBondContact O-N 3.14Å; M333-K337 WeakPolarHBondContact O-CB 3.4Å; M333-K337 PolarHBondContact O-N 2.85Å; M333-R543 VanDerWaalsContact CE-NH2 3.25Å; M333-R543 VanDerWaalsContact SD-CZ 3.58Å; M333-R543 PolarHBondContact SD-NH2 3.4Å
334V61.3Low55.2Low8 Ų863.6 Ų63.65%0.04832%0.324CS..Hα-helixtrans-70.6-35.9174.7-177.30000110.1A330 R336 K337 L338 P383 E387 I391A330-V334 WeakPolarHBondContact O-CB 3.43Å; A330-V334 WeakPolarHBondContact O-CG2 3.47Å; A330-V334 PolarHBondContact O-N 3.36Å; V334-R336 VanDerWaalsContact C-N 3.34Å; V334-R336 PolarHBondContact O-N 2.7Å; V334-K337 CarbonylContact O-C 3.56Å; V334-K337 VanDerWaalsContact O-CB 3.31Å; V334-K337 WeakPolarHBondContact O-CB 3.28Å; V334-K337 PolarHBondContact O-N 3.36Å; V334-L338 WeakPolarHBondContact O-CB 3.24Å; V334-L338 PolarHBondContact O-N 3.47Å; V334-P383 HydrophobicContact CG1-CB 4.3Å; V334-P383 HydrophobicContact CG1-CG 4.47Å; V334-E387 HydrophobicContact CG1-CB 3.85Å; V334-E387 HydrophobicContact CG1-CG 4.41Å; V334-E387 HydrophobicContact CG2-CB 4.15Å; V334-E387 HydrophobicContact CG2-CG 3.83Å; V334-E387 WeakPolarHBondContact CG2-OE1 3.47Å; V334-I391 HydrophobicContact CB-CD1 4.33Å; V334-I391 HydrophobicContact CB-CG1 4.38Å; V334-I391 HydrophobicContact CG1-CD1 3.28Å; V334-I391 HydrophobicContact CG1-CG1 3.75Å
335S60Low57.3Low19 Ų1959.7 Ų59.713%0.13331%0.307CS..Hα-helixtrans-66.7-34.4171.1-62.20000112.4C331 V332 R339C331-S335 VanDerWaalsContact O-CB 3.24Å; C331-S335 WeakPolarHBondContact O-CB 3.45Å; C331-S335 PolarHBondContact O-N 2.67Å; C331-S335 PolarHBondContact O-OG 2.82Å; V332-S335 PolarHBondContact O-N 3.18Å; S335-R339 PolarHBondContact O-N 2.96Å; S335-R339 VanDerWaalsContact O-N 3.1Å
336R63.9Low59.5Low136 Ų13653.2 Ų53.251%0.51327%0.271SS..Hα-helixtrans-68.8-39.4170.7-75.5176.1177.1177.10.2111.4V332 M333 V334 R339 A340V332-R336 WeakPolarHBondContact O-CB 3.17Å; V332-R336 WeakPolarHBondContact O-CG 3.26Å; V332-R336 PolarHBondContact O-N 3.44Å; M333-R336 CarbonylContact O-C 3.35Å; M333-R336 WeakPolarHBondContact O-CB 3.12Å; M333-R336 PolarHBondContact O-N 3.14Å; V334-R336 VanDerWaalsContact C-N 3.34Å; V334-R336 PolarHBondContact O-N 2.7Å; R336-R339 PolarHBondContact O-N 2.95Å; R336-A340 PolarHBondContact O-N 3.08Å
337K68.3Low61.6Low31 Ų3149.3 Ų49.314%0.13525%0.251CS..Hα-helixtrans-57.8-48.8171.8-172171.6179.4-171.10111M333 V334 R339 A340 L341 L381 L382 P383 W535M333-K337 WeakPolarHBondContact O-CB 3.4Å; M333-K337 PolarHBondContact O-N 2.85Å; V334-K337 CarbonylContact O-C 3.56Å; V334-K337 VanDerWaalsContact O-CB 3.31Å; V334-K337 WeakPolarHBondContact O-CB 3.28Å; V334-K337 PolarHBondContact O-N 3.36Å; K337-R339 VanDerWaalsContact C-N 3.34Å; K337-R339 PolarHBondContact O-N 3.02Å; K337-A340 PolarHBondContact O-N 3.49Å; K337-A340 VanDerWaalsContact O-N 3.16Å; K337-L341 HydrophobicContact CG-CD1 3.98Å; K337-L341 HydrophobicContact CG-CG 4.47Å; K337-L341 WeakPolarHBondContact O-CB 3.09Å; K337-L341 WeakPolarHBondContact O-CG 3.42Å; K337-L341 PolarHBondContact O-N 3.47Å; K337-L381 WeakPolarHBondContact CE-O 3.43Å; K337-L381 PolarHBondContact NZ-O 3Å; K337-L382 PolarHBondContact NZ-O 3.33Å; K337-P383 HydrophobicContact CD-CG 4.24Å; K337-P383 HydrophobicContact CG-CG 4.46Å; K337-W535 VanDerWaalsContact CA-CH2 3.44Å; K337-W535 HydrophobicContact CB-CH2 3.45Å; K337-W535 VanDerWaalsContact CB-CH2 3.45Å; K337-W535 HydrophobicContact CB-CZ2 4.09Å; K337-W535 HydrophobicContact CB-CZ3 4.26Å; K337-W535 HydrophobicContact CD-CH2 4.14Å; K337-W535 HydrophobicContact CD-CZ3 4.18Å; K337-W535 HydrophobicContact CG-CH2 3.43Å; K337-W535 VanDerWaalsContact CG-CH2 3.43Å; K337-W535 HydrophobicContact CG-CZ2 4.34Å; K337-W535 HydrophobicContact CG-CZ3 3.74Å
338L74.6Confident64.3Low0 Ų049.1 Ų49.10%024%0.244CC..Hα-helixtrans-61.1-41.5177.5-172.763.8000112.2V334 L341 Q342 I391 I398 T445 C448 F449 I452V334-L338 WeakPolarHBondContact O-CB 3.24Å; V334-L338 PolarHBondContact O-N 3.47Å; L338-L341 PolarHBondContact O-N 3.09Å; L338-Q342 PolarHBondContact O-N 2.7Å; L338-I391 HydrophobicContact CD2-CD1 4.26Å; L338-I391 HydrophobicContact CD2-CG2 4.45Å; L338-I398 HydrophobicContact CD2-CD1 3.69Å; L338-T445 HydrophobicContact CD2-CG2 3.58Å; L338-T445 HydrophobicContact CG-CG2 3.8Å; L338-C448 HydrophobicContact CD1-CB 4.32Å; L338-F449 HydrophobicContact CD1-CB 4.31Å; L338-F449 HydrophobicContact CD2-CB 4.31Å; L338-F449 HydrophobicContact CD2-CD2 4.13Å; L338-I452 HydrophobicContact CD1-CD1 3.47Å; L338-I452 VanDerWaalsContact CD1-CD1 3.47Å
339R70.7Confident66.8Low128 Ų12841.2 Ų41.248%0.48321%0.209SC..Hα-helixtrans-64.2-40.5173.3-78.7-176.6-72.5-161.8-2112.6S335 R336 K337 Q342S335-R339 PolarHBondContact O-N 2.96Å; S335-R339 VanDerWaalsContact O-N 3.1Å; R336-R339 PolarHBondContact O-N 2.95Å; K337-R339 VanDerWaalsContact C-N 3.34Å; K337-R339 PolarHBondContact O-N 3.02Å; R339-Q342 WeakPolarHBondContact O-CG 3.33Å; R339-Q342 PolarHBondContact O-N 2.68Å; R339-Q342 PolarHBondContact O-NE2 3.31Å
340A66.1Low69.2Low21 Ų2137.5 Ų37.517%0.17419%0.187CC..Hα-helixtrans-65.9-42.1175.300000112R336 K337 Q342 E343 W535R336-A340 PolarHBondContact O-N 3.08Å; K337-A340 PolarHBondContact O-N 3.49Å; K337-A340 VanDerWaalsContact O-N 3.16Å; A340-Q342 VanDerWaalsContact C-N 3.26Å; A340-Q342 PolarHBondContact O-N 2.87Å; A340-E343 WeakPolarHBondContact O-CB 3.3Å; A340-E343 PolarHBondContact O-N 2.82Å; A340-W535 HydrophobicContact CB-CD2 4.22Å; A340-W535 HydrophobicContact CB-CG 4.4Å; A340-W535 HydrophobicContact CB-CZ2 3.73Å
341L73.4Confident71.6Confident2 Ų236.1 Ų36.11%0.0118%0.175CC..Hα-helixtrans-62.1-32.8175.9-69.3169.7000112.3K337 L338 E343 I344 L347 L382 P383 I452 L532K337-L341 HydrophobicContact CG-CD1 3.98Å; K337-L341 HydrophobicContact CG-CG 4.47Å; K337-L341 WeakPolarHBondContact O-CB 3.09Å; K337-L341 WeakPolarHBondContact O-CG 3.42Å; K337-L341 PolarHBondContact O-N 3.47Å; L338-L341 PolarHBondContact O-N 3.09Å; L341-E343 PolarHBondContact O-N 2.71Å; L341-I344 HydrophobicContact CD2-CD1 4.23Å; L341-I344 WeakPolarHBondContact O-CB 3.48Å; L341-I344 PolarHBondContact O-N 3.02Å; L341-L347 HydrophobicContact CB-CD1 4.08Å; L341-L347 HydrophobicContact CD2-CD1 4.14Å; L341-L347 WeakPolarHBondContact O-CD1 2.89Å; L341-L382 HydrophobicContact CD1-CD2 4.29Å; L341-L382 HydrophobicContact CD2-CD2 3.94Å; L341-P383 HydrophobicContact CD1-CG 3.97Å; L341-I452 HydrophobicContact CD1-CD1 3.65Å; L341-L532 HydrophobicContact CD2-CD2 3.32Å
342Q76.5Confident73.8Confident46 Ų4635.4 Ų35.422%0.21517%0.171CC..Hα-helixtrans-61.9-31.5177.7100.9-161.6-18.100112.2L338 R339 A340 I344 T445 C448L338-Q342 PolarHBondContact O-N 2.7Å; R339-Q342 WeakPolarHBondContact O-CG 3.33Å; R339-Q342 PolarHBondContact O-N 2.68Å; R339-Q342 PolarHBondContact O-NE2 3.31Å; A340-Q342 VanDerWaalsContact C-N 3.26Å; A340-Q342 PolarHBondContact O-N 2.87Å; Q342-I344 VanDerWaalsContact C-N 3.28Å; Q342-T445 PolarHBondContact OE1-OG1 3Å; Q342-C448 HydrophobicContact CB-CB 4.01Å
343E69.6Low75.4Confident113 Ų11331.9 Ų31.953%0.52815%0.149SC..Hα-helixtrans-77.6-16.9178-54.8-58.7140.100111.9A340 L341 S345A340-E343 WeakPolarHBondContact O-CB 3.3Å; A340-E343 PolarHBondContact O-N 2.82Å; L341-E343 PolarHBondContact O-N 2.71Å; E343-S345 PolarHBondContact O-N 3Å
344I73.8Confident77Confident20 Ų2030.1 Ų30.110%0.10314%0.141CC..  trans-82.685178.8-58.3179.7000108.8L341 Q342 W346 L347 L528 Q531 L532L341-I344 HydrophobicContact CD2-CD1 4.23Å; L341-I344 WeakPolarHBondContact O-CB 3.48Å; L341-I344 PolarHBondContact O-N 3.02Å; Q342-I344 VanDerWaalsContact C-N 3.28Å; I344-W346 HydrophobicContact CG2-CB 4.3Å; I344-W346 PolarHBondContact O-N 3.39Å; I344-L347 HydrophobicContact CB-CD1 4.47Å; I344-L347 HydrophobicContact CB-CG 4.44Å; I344-L347 HydrophobicContact CG2-CG 4.18Å; I344-L347 PolarHBondContact O-N 3.34Å; I344-L528 HydrophobicContact CG2-CD2 3.31Å; I344-Q531 HydrophobicContact CD1-CB 4.47Å; I344-L532 HydrophobicContact CD1-CD2 3.59Å; I344-L532 HydrophobicContact CD1-CG 4.29Å
345S76.3Confident78.3Confident51 Ų5129.8 Ų29.836%0.35714%0.139SC..THydrogen-bonded Turntrans-63.7-9.9-177.878.20000114.5S277 E343 L347 K348S277-S345 WeakPolarHBondContact CB-O 3.42Å; S277-S345 WeakPolarHBondContact CB-OG 3.25Å; S277-S345 WeakPolarHBondContact OG-CB 3.18Å; S277-S345 PolarHBondContact OG-O 3.43Å; S277-S345 PolarHBondContact OG-OG 3.42Å; E343-S345 PolarHBondContact O-N 3Å; S345-L347 VanDerWaalsContact C-N 3.34Å; S345-K348 WeakPolarHBondContact O-CE 3.4Å; S345-K348 WeakPolarHBondContact O-CG 3.3Å
346W82.4Confident79.5Confident17 Ų1729.1 Ų29.16%0.06413%0.133CC..THydrogen-bonded Turntrans-76-18.2178.1-66.6102.7000113.8F259 L262 I280 I344 K348 V349 L350 V524 I527 L528F259-W346 AromaticContact CE1-CH2 3.97Å; F259-W346 HydrophobicContact CE1-CH2 3.97Å; F259-W346 HydrophobicContact CE1-CZ3 4.03Å; F259-W346 HydrophobicContact CZ-CH2 4.48Å; F259-W346 HydrophobicContact CZ-CZ3 4.36Å; L262-W346 HydrophobicContact CD1-CH2 4.12Å; L262-W346 HydrophobicContact CD1-CZ2 3.82Å; I280-W346 HydrophobicContact CB-CZ3 4.06Å; I280-W346 HydrophobicContact CG1-CH2 3.75Å; I280-W346 HydrophobicContact CG1-CZ3 3.68Å; I280-W346 HydrophobicContact CG2-CZ3 4.27Å; I344-W346 HydrophobicContact CG2-CB 4.3Å; I344-W346 PolarHBondContact O-N 3.39Å; W346-K348 VanDerWaalsContact C-N 3.27Å; W346-K348 PolarHBondContact O-N 3.37Å; W346-V349 HydrophobicContact CE3-CB 4.41Å; W346-V349 HydrophobicContact CE3-CG2 3.85Å; W346-V349 HydrophobicContact CZ3-CG2 4.34Å; W346-V349 WeakPolarHBondContact O-CB 3.36Å; W346-V349 PolarHBondContact O-N 3.3Å; W346-L350 PolarHBondContact O-N 3.17Å; W346-L350 VanDerWaalsContact O-N 3.16Å; W346-V524 HydrophobicContact CE3-CG2 4.1Å; W346-V524 HydrophobicContact CZ3-CG2 4.19Å; W346-I527 HydrophobicContact CD2-CD1 4.08Å; W346-I527 HydrophobicContact CD2-CG2 4.32Å; W346-I527 HydrophobicContact CE3-CD1 4.41Å; W346-I527 HydrophobicContact CG-CG2 3.97Å; W346-I527 HydrophobicContact CH2-CD1 4.01Å; W346-I527 HydrophobicContact CZ2-CD1 3.65Å; W346-I527 HydrophobicContact CZ3-CD1 4.37Å; W346-L528 HydrophobicContact CB-CD1 4.32Å; W346-L528 HydrophobicContact CB-CD2 3.41Å; W346-L528 VanDerWaalsContact CB-CD2 3.41Å; W346-L528 HydrophobicContact CB-CG 3.74Å
347L85Confident80.4Confident3 Ų322.9 Ų22.92%0.01611%0.11CC..Hα-helixtrans-61.9-34.8179.4-70.4174.8000112.6L341 I344 S345 L350 K351 L382 L455 L528L341-L347 HydrophobicContact CB-CD1 4.08Å; L341-L347 HydrophobicContact CD2-CD1 4.14Å; L341-L347 WeakPolarHBondContact O-CD1 2.89Å; I344-L347 HydrophobicContact CB-CD1 4.47Å; I344-L347 HydrophobicContact CB-CG 4.44Å; I344-L347 HydrophobicContact CG2-CG 4.18Å; I344-L347 PolarHBondContact O-N 3.34Å; S345-L347 VanDerWaalsContact C-N 3.34Å; L347-L350 PolarHBondContact O-N 3.06Å; L347-K351 WeakPolarHBondContact O-CB 3.3Å; L347-K351 PolarHBondContact O-N 3.31Å; L347-L382 HydrophobicContact CD2-CD2 4.26Å; L347-L455 HydrophobicContact CD2-CD1 3.92Å; L347-L528 HydrophobicContact CD2-CD1 4.42Å; L347-L528 HydrophobicContact CD2-CD2 3.85Å; L347-L528 HydrophobicContact CG-CD2 4.09Å
348K88.5Confident81.2Confident31 Ų3124.7 Ų24.714%0.13512%0.119CC..Hα-helixtrans-68.3-33.1174.552.4167.9-169.7-167.80112.7S277 N278 I281 S345 W346 K351 V352 E421S277-K348 WeakPolarHBondContact OG-CE 3.16Å; S277-K348 PolarHBondContact OG-NZ 3.41Å; N278-K348 PolarHBondContact OD1-NZ 3Å; I281-K348 HydrophobicContact CD1-CB 4.28Å; I281-K348 HydrophobicContact CD1-CD 3.68Å; I281-K348 HydrophobicContact CD1-CG 3.9Å; S345-K348 WeakPolarHBondContact O-CE 3.4Å; S345-K348 WeakPolarHBondContact O-CG 3.3Å; W346-K348 VanDerWaalsContact C-N 3.27Å; W346-K348 PolarHBondContact O-N 3.37Å; K348-K351 PolarHBondContact O-N 3.19Å; K348-V352 WeakPolarHBondContact O-CG2 3.42Å; K348-V352 PolarHBondContact O-N 2.92Å; K348-E421 HydrophobicContact CB-CB 3.94Å; K348-E421 VanDerWaalsContact CB-CD 3.48Å; K348-E421 HydrophobicContact CB-CG 3.8Å
349V85Confident81.5Confident1 Ų128.4 Ų28.41%0.00614%0.138CC..Hα-helixtrans-63.6-48.7175.7-173.60000109I280 I281 W346 K351 V352 I353 V524I280-V349 HydrophobicContact CB-CG1 4.4Å; I280-V349 HydrophobicContact CG2-CG1 3.63Å; I281-V349 HydrophobicContact CD1-CG2 4.39Å; I281-V349 HydrophobicContact CG1-CB 4.46Å; I281-V349 HydrophobicContact CG1-CG2 4.08Å; W346-V349 HydrophobicContact CE3-CB 4.41Å; W346-V349 HydrophobicContact CE3-CG2 3.85Å; W346-V349 HydrophobicContact CZ3-CG2 4.34Å; W346-V349 WeakPolarHBondContact O-CB 3.36Å; W346-V349 PolarHBondContact O-N 3.3Å; V349-K351 VanDerWaalsContact C-N 3.32Å; V349-K351 PolarHBondContact O-N 3.49Å; V349-V352 PolarHBondContact O-N 3.18Å; V349-I353 HydrophobicContact CG1-CD1 4.06Å; V349-I353 WeakPolarHBondContact O-CG1 3.34Å; V349-I353 PolarHBondContact O-N 3.47Å; V349-V524 HydrophobicContact CB-CG1 4.29Å; V349-V524 HydrophobicContact CG1-CG1 4.29Å; V349-V524 HydrophobicContact CG1-CG2 3.82Å
350L88.5Confident81.9Confident2 Ų223.6 Ų23.61%0.0112%0.121CC..Hα-helixtrans-61.6-40.4176.9-177.865000112W346 L347 V352 I353 C354 L378 L455 V524 L525 L528W346-L350 PolarHBondContact O-N 3.17Å; W346-L350 VanDerWaalsContact O-N 3.16Å; L347-L350 PolarHBondContact O-N 3.06Å; L350-V352 PolarHBondContact O-N 2.73Å; L350-I353 PolarHBondContact O-N 2.82Å; L350-C354 PolarHBondContact O-N 2.95Å; L350-C354 PolarHBondContact O-SG 2.9Å; L350-L378 HydrophobicContact CD2-CD2 3.2Å; L350-L378 HydrophobicContact CD2-CG 4.47Å; L350-L455 HydrophobicContact CB-CD2 4.38Å; L350-L455 HydrophobicContact CD2-CD1 4.34Å; L350-L455 HydrophobicContact CD2-CD2 3.85Å; L350-L455 HydrophobicContact CG-CD2 3.81Å; L350-V524 HydrophobicContact CB-CG1 4.17Å; L350-L525 HydrophobicContact CD1-CD2 3.68Å; L350-L525 HydrophobicContact CD1-CG 4.38Å; L350-L525 HydrophobicContact CD2-CD2 4.12Å; L350-L528 HydrophobicContact CB-CD1 3.85Å; L350-L528 HydrophobicContact CD2-CD1 3.81Å; L350-L528 HydrophobicContact CG-CD1 4.41Å
351K92Very high82.4Confident0 Ų025 Ų250%013%0.128CC..Hα-helixtrans-57.6-49.1175.5-166.9-78.4-176-157.50111.5L347 K348 V349 I353 C354 N355 E421 D422 R451 C454 L455 Y458L347-K351 WeakPolarHBondContact O-CB 3.3Å; L347-K351 PolarHBondContact O-N 3.31Å; K348-K351 PolarHBondContact O-N 3.19Å; V349-K351 VanDerWaalsContact C-N 3.32Å; V349-K351 PolarHBondContact O-N 3.49Å; K351-I353 VanDerWaalsContact C-N 3.35Å; K351-I353 PolarHBondContact O-N 3.37Å; K351-C354 PolarHBondContact O-N 3.4Å; K351-N355 WeakPolarHBondContact CD-ND2 3.13Å; K351-N355 PolarHBondContact NZ-ND2 3.49Å; K351-N355 PolarHBondContact NZ-OD1 3.32Å; K351-N355 PolarHBondContact O-N 3.37Å; K351-E421 HydrophobicContact CD-CG 4.37Å; K351-D422 WeakPolarHBondContact CE-OD1 3.27Å; K351-D422 VanDerWaalsContact NZ-CG 3.31Å; K351-D422 IonicContact NZ-OD1 3.09Å; K351-D422 PolarHBondContact NZ-OD1 2.77Å; K351-D422 IonicContact NZ-OD2 3.83Å; K351-D422 PolarHBondContact NZ-OD2 3.42Å; K351-R451 HydrophobicContact CG-CG 4.41Å; K351-C454 HydrophobicContact CG-CB 4.17Å; K351-L455 HydrophobicContact CB-CD2 4.44Å; K351-Y458 HydrophobicContact CG-CE2 4.44Å; K351-Y458 PolarHBondContact NZ-OH 3.41Å
352V86.9Confident82.5Confident1 Ų127.8 Ų27.81%0.00614%0.141CC..Hα-helixtrans-61-42.7178168.70000111.6I281 V284 M288 K348 V349 L350 N355 W356 E421 V425I281-V352 HydrophobicContact CD1-CG2 4.5Å; I281-V352 HydrophobicContact CG1-CG2 4.42Å; V284-V352 HydrophobicContact CG1-CG1 4.49Å; M288-V352 HydrophobicContact CE-CG1 4.42Å; K348-V352 WeakPolarHBondContact O-CG2 3.42Å; K348-V352 PolarHBondContact O-N 2.92Å; V349-V352 PolarHBondContact O-N 3.18Å; L350-V352 PolarHBondContact O-N 2.73Å; V352-N355 WeakPolarHBondContact O-CB 3.49Å; V352-N355 PolarHBondContact O-N 3.43Å; V352-W356 PolarHBondContact O-N 3.24Å; V352-E421 HydrophobicContact CG2-CB 3.86Å; V352-E421 HydrophobicContact CG2-CG 3.95Å; V352-V425 HydrophobicContact CG1-CG1 3.98Å; V352-V425 HydrophobicContact CG1-CG2 4.21Å; V352-V425 HydrophobicContact CG2-CG1 4.4Å; V352-V425 HydrophobicContact CG2-CG2 4.18Å
353I84.7Confident82.4Confident1 Ų126.7 Ų26.71%0.00514%0.136CC..Hα-helixtrans-60.5-48.9174.5-75.8169.1000111V284 V349 L350 K351 N355 W356 L357 V520 I521V284-I353 HydrophobicContact CG1-CG1 4.23Å; V349-I353 HydrophobicContact CG1-CD1 4.06Å; V349-I353 WeakPolarHBondContact O-CG1 3.34Å; V349-I353 PolarHBondContact O-N 3.47Å; L350-I353 PolarHBondContact O-N 2.82Å; K351-I353 VanDerWaalsContact C-N 3.35Å; K351-I353 PolarHBondContact O-N 3.37Å; I353-N355 VanDerWaalsContact C-N 3.34Å; I353-N355 PolarHBondContact O-N 3.35Å; I353-W356 PolarHBondContact O-N 2.77Å; I353-W356 VanDerWaalsContact O-N 3.13Å; I353-L357 HydrophobicContact CG2-CD1 3.78Å; I353-L357 HydrophobicContact CG2-CG 4.26Å; I353-L357 WeakPolarHBondContact O-CG 3.11Å; I353-L357 PolarHBondContact O-N 2.79Å; I353-V520 HydrophobicContact CD1-CG1 4.4Å; I353-I521 HydrophobicContact CD1-CG1 4.02Å; I353-I521 HydrophobicContact CG1-CG1 4.44Å; I353-I521 HydrophobicContact CG2-CD1 3.87Å; I353-I521 HydrophobicContact CG2-CG1 3.54Å
354C89.5Confident82.7Confident2 Ų221.3 Ų21.31%0.01411%0.111CC..Hα-helixtrans-64.4-38-178.9-68.70000112.5L350 K351 W356 L357 Q358 Y458 F462L350-C354 PolarHBondContact O-N 2.95Å; L350-C354 PolarHBondContact O-SG 2.9Å; K351-C354 PolarHBondContact O-N 3.4Å; C354-W356 VanDerWaalsContact C-N 3.28Å; C354-W356 PolarHBondContact O-N 2.81Å; C354-L357 PolarHBondContact O-N 3.48Å; C354-Q358 WeakPolarHBondContact O-CB 3.49Å; C354-Q358 PolarHBondContact O-N 2.87Å; C354-Y458 HydrophobicContact CB-CD1 4.25Å; C354-Y458 HydrophobicContact CB-CD2 3.27Å; C354-Y458 HydrophobicContact CB-CE2 3.67Å; C354-Y458 HydrophobicContact CB-CG 3.65Å; C354-F462 HydrophobicContact CB-CE2 4.36Å; C354-F462 HydrophobicContact CB-CZ 4.18Å
355N88.5Confident82.8Confident1 Ų127.5 Ų27.51%0.00513%0.133CC..Hα-helixtrans-53.1-48.2171.1-81.4-35.6000111K351 V352 I353 Q358 L359 D422 L429 L431 Y458K351-N355 WeakPolarHBondContact CD-ND2 3.13Å; K351-N355 PolarHBondContact NZ-ND2 3.49Å; K351-N355 PolarHBondContact NZ-OD1 3.32Å; K351-N355 PolarHBondContact O-N 3.37Å; V352-N355 WeakPolarHBondContact O-CB 3.49Å; V352-N355 PolarHBondContact O-N 3.43Å; I353-N355 VanDerWaalsContact C-N 3.34Å; I353-N355 PolarHBondContact O-N 3.35Å; N355-Q358 PolarHBondContact O-N 3.38Å; N355-L359 WeakPolarHBondContact O-CG 3.39Å; N355-L359 PolarHBondContact O-N 2.8Å; N355-D422 PolarHBondContact ND2-OD1 3.1Å; N355-L429 HydrophobicContact CB-CD1 3.46Å; N355-L429 VanDerWaalsContact CB-CD1 3.46Å; N355-L431 HydrophobicContact CB-CD1 3.82Å; N355-L431 WeakPolarHBondContact OD1-CD1 3.24Å; N355-Y458 PolarHBondContact OD1-OH 2.81Å
356W84.5Confident82.5Confident4 Ų426.2 Ų26.22%0.01513%0.126CC..Hα-helixtrans-69.4-46.3-178.4-178.478.1000111.9M288 I291 V352 I353 C354 Q358 L359 H360 E363 L429 I517M288-W356 HydrophobicContact CE-CB 3.33Å; M288-W356 HydrophobicContact CE-CD2 3.86Å; M288-W356 HydrophobicContact CE-CE3 4.34Å; M288-W356 HydrophobicContact CE-CG 3.41Å; M288-W356 VanDerWaalsContact CE-CG 3.41Å; M288-W356 HydrophobicContact CG-CD2 4.19Å; M288-W356 HydrophobicContact CG-CG 3.99Å; M288-W356 HydrophobicContact SD-CB 4.06Å; M288-W356 HydrophobicContact SD-CG 3.89Å; I291-W356 HydrophobicContact CD1-CH2 4.13Å; I291-W356 HydrophobicContact CD1-CZ2 3.8Å; V352-W356 PolarHBondContact O-N 3.24Å; I353-W356 PolarHBondContact O-N 2.77Å; I353-W356 VanDerWaalsContact O-N 3.13Å; C354-W356 VanDerWaalsContact C-N 3.28Å; C354-W356 PolarHBondContact O-N 2.81Å; W356-Q358 PolarHBondContact O-N 2.75Å; W356-L359 CarbonylContact O-C 3.46Å; W356-L359 WeakPolarHBondContact O-CA 3.31Å; W356-L359 WeakPolarHBondContact O-CB 3.29Å; W356-L359 PolarHBondContact O-N 3.21Å; W356-H360 AromaticContact CD1-CD2 3.31Å; W356-H360 AromaticContact CD1-NE2 3.56Å; W356-H360 AromaticContact CD2-CD2 3.81Å; W356-H360 AromaticContact CE2-CD2 3.42Å; W356-H360 VanDerWaalsContact CE2-CD2 3.42Å; W356-H360 AromaticContact CE2-CG 3.95Å; W356-H360 AromaticContact CE2-NE2 3.89Å; W356-H360 AromaticContact CG-CD2 3.76Å; W356-H360 AromaticContact NE1-CD2 3.06Å; W356-H360 PolarHBondContact NE1-CD2 3.16Å; W356-H360 AromaticContact NE1-CG 3.96Å; W356-H360 AromaticContact NE1-NE2 3.14Å; W356-H360 PolarHBondContact NE1-NE2 3.46Å; W356-H360 VanDerWaalsContact NE1-NE2 3.14Å; W356-H360 PolarHBondContact O-CD2 3.42Å; W356-H360 VanDerWaalsContact O-CD2 3.24Å; W356-H360 PolarHBondContact O-N 2.96Å; W356-E363 HydrophobicContact CH2-CB 3.92Å; W356-E363 HydrophobicContact CH2-CG 3.49Å; W356-E363 VanDerWaalsContact CH2-CG 3.49Å; W356-E363 HydrophobicContact CZ2-CG 4.15Å; W356-E363 HydrophobicContact CZ3-CB 3.84Å; W356-E363 HydrophobicContact CZ3-CG 3.97Å; W356-L429 HydrophobicContact CB-CD2 3.73Å; W356-L429 HydrophobicContact CG-CD2 4.1Å; W356-I517 HydrophobicContact CE3-CG2 4.35Å; W356-I517 HydrophobicContact CH2-CD1 3.68Å; W356-I517 HydrophobicContact CH2-CG2 4.44Å; W356-I517 HydrophobicContact CZ2-CD1 3.98Å; W356-I517 HydrophobicContact CZ3-CD1 4.07Å; W356-I517 HydrophobicContact CZ3-CG2 3.86Å
357L84.2Confident82.1Confident5 Ų526.3 Ų26.33%0.02613%0.127CC..Hα-helixtrans-57.6-32.7176.7-72.1174.7000112.9I353 C354 L359 H360 E363 L364 M367 F462 I521I353-L357 HydrophobicContact CG2-CD1 3.78Å; I353-L357 HydrophobicContact CG2-CG 4.26Å; I353-L357 WeakPolarHBondContact O-CG 3.11Å; I353-L357 PolarHBondContact O-N 2.79Å; C354-L357 PolarHBondContact O-N 3.48Å; L357-L359 VanDerWaalsContact C-N 3.3Å; L357-L359 PolarHBondContact O-N 2.77Å; L357-H360 CarbonylContact O-C 3.6Å; L357-H360 PolarHBondContact O-N 2.9Å; L357-E363 HydrophobicContact CD2-CB 4.13Å; L357-L364 HydrophobicContact CB-CD1 3.95Å; L357-L364 HydrophobicContact CD1-CD1 4.46Å; L357-M367 HydrophobicContact CD1-SD 3.67Å; L357-M367 HydrophobicContact CD2-SD 4.33Å; L357-F462 HydrophobicContact CB-CZ 4.18Å; L357-I521 HydrophobicContact CD1-CD1 4.13Å; L357-I521 HydrophobicContact CD2-CD1 4.25Å
358Q84.4Confident81.2Confident70 Ų7026.4 Ų26.433%0.32713%0.129SC..Hα-helixtrans-64.2-34.7173.2-178.6-1801800112.5C354 N355 W356 Y458 E461 F462C354-Q358 WeakPolarHBondContact O-CB 3.49Å; C354-Q358 PolarHBondContact O-N 2.87Å; N355-Q358 PolarHBondContact O-N 3.38Å; W356-Q358 PolarHBondContact O-N 2.75Å; Q358-Y458 VanDerWaalsContact OE1-CE1 3.3Å; Q358-E461 VanDerWaalsContact CD-OE2 3.24Å; Q358-E461 PolarHBondContact NE2-OE1 3.44Å; Q358-E461 PolarHBondContact NE2-OE2 3.22Å; Q358-F462 HydrophobicContact CB-CE1 4.37Å
359L81.1Confident80.5Confident77 Ų7726.7 Ų26.740%0.40314%0.137SC..Hα-helixtrans-82.4-16.9178.7-61.2172.2000112.9N355 W356 L357 P361 L429 L431N355-L359 WeakPolarHBondContact O-CG 3.39Å; N355-L359 PolarHBondContact O-N 2.8Å; W356-L359 CarbonylContact O-C 3.46Å; W356-L359 WeakPolarHBondContact O-CA 3.31Å; W356-L359 WeakPolarHBondContact O-CB 3.29Å; W356-L359 PolarHBondContact O-N 3.21Å; L357-L359 VanDerWaalsContact C-N 3.3Å; L357-L359 PolarHBondContact O-N 2.77Å; L359-P361 WeakPolarHBondContact O-CD 3.47Å; L359-L429 HydrophobicContact CD1-CB 4.04Å; L359-L429 HydrophobicContact CD1-CD2 4.4Å; L359-L429 WeakPolarHBondContact CD1-O 3.13Å; L359-L431 HydrophobicContact CD1-CD2 3.86Å; L359-L431 HydrophobicContact CD1-CG 4.45Å; L359-L431 HydrophobicContact CD2-CD2 4.12Å; L359-L431 HydrophobicContact CG-CD2 4.17Å
360H78.6Confident79.8Confident27 Ų2726.7 Ų26.713%0.12514%0.138CC..  trans-124.573.4-176.2-67.1-77.8000112.1W356 L357 E362 E363 L364W356-H360 AromaticContact CD1-CD2 3.31Å; W356-H360 AromaticContact CD1-NE2 3.56Å; W356-H360 AromaticContact CD2-CD2 3.81Å; W356-H360 AromaticContact CE2-CD2 3.42Å; W356-H360 VanDerWaalsContact CE2-CD2 3.42Å; W356-H360 AromaticContact CE2-CG 3.95Å; W356-H360 AromaticContact CE2-NE2 3.89Å; W356-H360 AromaticContact CG-CD2 3.76Å; W356-H360 AromaticContact NE1-CD2 3.06Å; W356-H360 PolarHBondContact NE1-CD2 3.16Å; W356-H360 AromaticContact NE1-CG 3.96Å; W356-H360 AromaticContact NE1-NE2 3.14Å; W356-H360 PolarHBondContact NE1-NE2 3.46Å; W356-H360 VanDerWaalsContact NE1-NE2 3.14Å; W356-H360 PolarHBondContact O-CD2 3.42Å; W356-H360 VanDerWaalsContact O-CD2 3.24Å; W356-H360 PolarHBondContact O-N 2.96Å; L357-H360 CarbonylContact O-C 3.6Å; L357-H360 PolarHBondContact O-N 2.9Å; H360-E362 WeakPolarHBondContact CA-OE1 3.31Å; H360-E362 VanDerWaalsContact CB-OE1 3.3Å; H360-E362 WeakPolarHBondContact CB-OE1 3.36Å; H360-E362 IonicContact CG-OE1 3.5Å; H360-E362 IonicContact ND1-OE1 3.47Å; H360-E362 PolarHBondContact ND1-OE1 3.31Å; H360-E362 PolarHBondContact O-N 2.97Å; H360-E362 VanDerWaalsContact O-N 3.1Å; H360-E363 HydrophobicContact CB-CB 4.05Å; H360-E363 HydrophobicContact CB-CG 3.86Å; H360-E363 WeakPolarHBondContact O-CB 3.06Å; H360-E363 PolarHBondContact O-N 2.96Å; H360-L364 PolarHBondContact O-N 3.39Å
361P78Confident79Confident50 Ų5026.7 Ų26.733%0.32514%0.138SC..Hα-helixtrans-58.6-23.7-177.3-23.933.9000114.9L359 R365L359-P361 WeakPolarHBondContact O-CD 3.47Å; P361-R365 WeakPolarHBondContact O-CB 3.42Å; P361-R365 PolarHBondContact O-N 3.46Å
362E74.9Confident78.4Confident61 Ų6127.1 Ų27.129%0.28514%0.14SC..Hα-helixtrans-66.3-42.6173.764.3-69.5169.900112.4H306 H360 R365 A366H306-E362 WeakPolarHBondContact CE1-CG 3.29Å; H360-E362 WeakPolarHBondContact CA-OE1 3.31Å; H360-E362 VanDerWaalsContact CB-OE1 3.3Å; H360-E362 WeakPolarHBondContact CB-OE1 3.36Å; H360-E362 IonicContact CG-OE1 3.5Å; H360-E362 IonicContact ND1-OE1 3.47Å; H360-E362 PolarHBondContact ND1-OE1 3.31Å; H360-E362 PolarHBondContact O-N 2.97Å; H360-E362 VanDerWaalsContact O-N 3.1Å; E362-R365 WeakPolarHBondContact O-CB 3.33Å; E362-R365 PolarHBondContact O-N 3.29Å; E362-A366 PolarHBondContact O-N 2.95Å; E362-A366 VanDerWaalsContact O-N 3.12Å
363E73.3Confident77.9Confident23 Ų2328.6 Ų28.611%0.10715%0.152CC..Hα-helixtrans-71.8-38.9176-58.6-59.3143.400110.5S305 H306 W356 L357 H360 R365 A366 M367S305-E363 WeakPolarHBondContact CB-OE1 3.39Å; S305-E363 VanDerWaalsContact O-OE2 3.06Å; S305-E363 PolarHBondContact OG-OE1 3.48Å; H306-E363 IonicContact CE1-OE1 3.2Å; H306-E363 PolarHBondContact CE1-OE1 2.79Å; H306-E363 IonicContact ND1-OE1 3.21Å; H306-E363 PolarHBondContact ND1-OE1 2.97Å; W356-E363 HydrophobicContact CH2-CB 3.92Å; W356-E363 HydrophobicContact CH2-CG 3.49Å; W356-E363 VanDerWaalsContact CH2-CG 3.49Å; W356-E363 HydrophobicContact CZ2-CG 4.15Å; W356-E363 HydrophobicContact CZ3-CB 3.84Å; W356-E363 HydrophobicContact CZ3-CG 3.97Å; L357-E363 HydrophobicContact CD2-CB 4.13Å; H360-E363 HydrophobicContact CB-CB 4.05Å; H360-E363 HydrophobicContact CB-CG 3.86Å; H360-E363 WeakPolarHBondContact O-CB 3.06Å; H360-E363 PolarHBondContact O-N 2.96Å; E363-R365 PolarHBondContact O-N 2.87Å; E363-A366 PolarHBondContact O-N 2.85Å; E363-A366 VanDerWaalsContact O-N 3.15Å; E363-M367 PolarHBondContact O-N 2.98Å
364L76.9Confident77.5Confident1 Ų132.3 Ų32.31%0.00517%0.166CC..Hα-helixtrans-56.6-40170.6-167.272.3000111.5L357 H360 M367 W372 F462 F467L357-L364 HydrophobicContact CB-CD1 3.95Å; L357-L364 HydrophobicContact CD1-CD1 4.46Å; H360-L364 PolarHBondContact O-N 3.39Å; L364-M367 PolarHBondContact O-N 3.11Å; L364-W372 HydrophobicContact CD1-CH2 3.52Å; L364-W372 HydrophobicContact CD1-CZ2 3.9Å; L364-W372 HydrophobicContact CG-CH2 4.08Å; L364-W372 HydrophobicContact CG-CZ2 4.09Å; L364-F462 HydrophobicContact CD1-CD1 3.77Å; L364-F462 HydrophobicContact CD1-CD2 4.36Å; L364-F462 HydrophobicContact CD1-CE1 3.67Å; L364-F462 HydrophobicContact CD1-CE2 4.27Å; L364-F462 HydrophobicContact CD1-CG 4.13Å; L364-F462 HydrophobicContact CD1-CZ 3.93Å; L364-F462 HydrophobicContact CD2-CD1 3.82Å; L364-F462 HydrophobicContact CD2-CE1 4.16Å; L364-F462 HydrophobicContact CG-CD1 4.49Å; L364-F467 HydrophobicContact CB-CE2 4.32Å; L364-F467 HydrophobicContact CB-CZ 4.29Å; L364-F467 HydrophobicContact CD2-CE2 4.18Å; L364-F467 HydrophobicContact CD2-CZ 3.88Å; L364-F467 HydrophobicContact CG-CE2 3.96Å; L364-F467 HydrophobicContact CG-CZ 4.09Å
365R76.7Confident77.2Confident150 Ų15032.6 Ų32.657%0.56617%0.167SC*.Hα-helixtrans-71.5-31.1178.6-171.9-177.1-61.31162.5112.7P361 E362 E363 M367 F467P361-R365 WeakPolarHBondContact O-CB 3.42Å; P361-R365 PolarHBondContact O-N 3.46Å; E362-R365 WeakPolarHBondContact O-CB 3.33Å; E362-R365 PolarHBondContact O-N 3.29Å; E363-R365 PolarHBondContact O-N 2.87Å; R365-M367 PolarHBondContact O-N 2.88Å; R365-F467 VanDerWaalsContact CA-CE2 3.48Å; R365-F467 HydrophobicContact CB-CD2 4.14Å; R365-F467 HydrophobicContact CB-CE2 3.91Å; R365-F467 HydrophobicContact CB-CZ 4.09Å; R365-F467 HydrophobicContact CG-CD2 4.15Å; R365-F467 HydrophobicContact CG-CE2 4.41Å; R365-F467 HydrophobicContact CG-CG 4.24Å
366A69.9Low77Confident24 Ų2433.1 Ų33.120%0.19817%0.17CC..Hα-helixtrans-71.4-18.9178.500000112.8L308 E362 E363 G368L308-A366 WeakPolarHBondContact CB-O 3.28Å; E362-A366 PolarHBondContact O-N 2.95Å; E362-A366 VanDerWaalsContact O-N 3.12Å; E363-A366 PolarHBondContact O-N 2.85Å; E363-A366 VanDerWaalsContact O-N 3.15Å; A366-G368 PolarHBondContact O-N 3.09Å
367M72.3Confident76.8Confident18 Ų1834.7 Ų34.79%0.08918%0.182CC..  trans-57.9126.4180-72.9-168.86100113.1L357 E363 L364 R365 W372 I521L357-M367 HydrophobicContact CD1-SD 3.67Å; L357-M367 HydrophobicContact CD2-SD 4.33Å; E363-M367 PolarHBondContact O-N 2.98Å; L364-M367 PolarHBondContact O-N 3.11Å; R365-M367 PolarHBondContact O-N 2.88Å; M367-W372 HydrophobicContact CB-CZ2 4.07Å; M367-W372 PolarHBondContact O-NE1 2.86Å; M367-W372 HydrophobicContact SD-CH2 4.27Å; M367-W372 HydrophobicContact SD-CZ2 3.99Å; M367-I521 HydrophobicContact CE-CG2 4.02Å
368G67.7Low76.8Confident6 Ų634.5 Ų34.56%0.06218%0.181CC..  trans-68154.7177.400000113.9A366 G370 S371 W372A366-G368 PolarHBondContact O-N 3.09Å; G368-G370 VanDerWaalsContact C-N 3.26Å; G368-G370 PolarHBondContact O-N 2.88Å; G368-S371 WeakPolarHBondContact O-CB 3.39Å; G368-S371 PolarHBondContact O-N 2.77Å; G368-W372 PolarHBondContact O-N 3.15Å
369A72.5Confident76.9Confident36 Ų3631.1 Ų31.130%0.29817%0.165SC..Hα-helixtrans-55.6-37-179.100000113.7S371 W372 A373A369-S371 VanDerWaalsContact C-N 3.32Å; A369-S371 PolarHBondContact O-N 2.81Å; A369-W372 WeakPolarHBondContact O-CB 3.32Å; A369-W372 PolarHBondContact O-N 3.48Å; A369-A373 PolarHBondContact O-N 2.89Å
370G70.2Confident77.1Confident2 Ų229.7 Ų29.72%0.02116%0.157CC..Hα-helixtrans-62.7-36.2176.500000113.2G368 A373 R374G368-G370 VanDerWaalsContact C-N 3.26Å; G368-G370 PolarHBondContact O-N 2.88Å; G370-A373 PolarHBondContact O-N 3.13Å; G370-R374 WeakPolarHBondContact O-CG 3.13Å; G370-R374 PolarHBondContact O-N 3.29Å
371S72.1Confident77.2Confident2 Ų229.3 Ų29.31%0.01416%0.156CC..Hα-helixtrans-66.5-39.7174.8-57.10000111.2G368 A369 R374 F375 E522G368-S371 WeakPolarHBondContact O-CB 3.39Å; G368-S371 PolarHBondContact O-N 2.77Å; A369-S371 VanDerWaalsContact C-N 3.32Å; A369-S371 PolarHBondContact O-N 2.81Å; S371-R374 PolarHBondContact O-N 3.28Å; S371-F375 WeakPolarHBondContact O-CB 3.39Å; S371-F375 PolarHBondContact O-N 3.38Å; S371-E522 VanDerWaalsContact OG-CG 3.25Å; S371-E522 WeakPolarHBondContact OG-CG 3.47Å; S371-E522 PolarHBondContact OG-OE1 3.43Å
372W80Confident77.6Confident9 Ų927 Ų273%0.03414%0.141CC..Hα-helixtrans-64.7-44.3173.8-70.4116.2000112.7L364 M367 G368 A369 R374 F375 V376 F462 T468 L470L364-W372 HydrophobicContact CD1-CH2 3.52Å; L364-W372 HydrophobicContact CD1-CZ2 3.9Å; L364-W372 HydrophobicContact CG-CH2 4.08Å; L364-W372 HydrophobicContact CG-CZ2 4.09Å; M367-W372 HydrophobicContact CB-CZ2 4.07Å; M367-W372 PolarHBondContact O-NE1 2.86Å; M367-W372 HydrophobicContact SD-CH2 4.27Å; M367-W372 HydrophobicContact SD-CZ2 3.99Å; G368-W372 PolarHBondContact O-N 3.15Å; A369-W372 WeakPolarHBondContact O-CB 3.32Å; A369-W372 PolarHBondContact O-N 3.48Å; W372-R374 VanDerWaalsContact C-N 3.33Å; W372-R374 PolarHBondContact O-N 2.71Å; W372-F375 HydrophobicContact CE3-CD1 4.28Å; W372-F375 HydrophobicContact CZ3-CD1 4.23Å; W372-F375 PolarHBondContact O-N 3.22Å; W372-V376 WeakPolarHBondContact O-CB 3.43Å; W372-V376 VanDerWaalsContact O-CG2 3.27Å; W372-V376 WeakPolarHBondContact O-CG2 3.38Å; W372-V376 PolarHBondContact O-N 2.94Å; W372-F462 HydrophobicContact CH2-CB 4.11Å; W372-F462 HydrophobicContact CH2-CD2 4.03Å; W372-F462 HydrophobicContact CH2-CG 4.13Å; W372-F462 HydrophobicContact CZ3-CB 4.07Å; W372-F462 AromaticContact CZ3-CD2 3.86Å; W372-F462 HydrophobicContact CZ3-CD2 3.86Å; W372-F462 HydrophobicContact CZ3-CG 4.24Å; W372-T468 HydrophobicContact CH2-CG2 3.64Å; W372-T468 HydrophobicContact CZ2-CG2 3.55Å; W372-T468 HydrophobicContact CZ3-CG2 4.3Å; W372-L470 HydrophobicContact CE3-CD1 3.73Å; W372-L470 HydrophobicContact CE3-CD2 4.35Å; W372-L470 HydrophobicContact CE3-CG 4.22Å; W372-L470 HydrophobicContact CZ3-CD1 3.75Å
373A76.4Confident78.1Confident32 Ų3224 Ų2426%0.26413%0.127SC..Hα-helixtrans-60.5-42.3176.100000112.1N313 A369 G370 V376 S377N313-A373 VanDerWaalsContact OD1-CB 3.23Å; N313-A373 WeakPolarHBondContact OD1-CB 3.38Å; A369-A373 PolarHBondContact O-N 2.89Å; G370-A373 PolarHBondContact O-N 3.13Å; A373-V376 PolarHBondContact O-N 2.92Å; A373-S377 WeakPolarHBondContact O-CB 3.22Å; A373-S377 PolarHBondContact O-N 3.4Å
374R75.9Confident78.7Confident79 Ų7925.1 Ų25.130%0.29814%0.135SC..Hα-helixtrans-65.9-45.2174.8-70.8-177.7-172.6110.82.6112.2G370 S371 W372 V376 S377 L378 L525G370-R374 WeakPolarHBondContact O-CG 3.13Å; G370-R374 PolarHBondContact O-N 3.29Å; S371-R374 PolarHBondContact O-N 3.28Å; W372-R374 VanDerWaalsContact C-N 3.33Å; W372-R374 PolarHBondContact O-N 2.71Å; R374-V376 VanDerWaalsContact C-N 3.33Å; R374-V376 PolarHBondContact O-N 3.4Å; R374-S377 WeakPolarHBondContact O-CB 3.44Å; R374-S377 PolarHBondContact O-N 2.99Å; R374-L378 WeakPolarHBondContact O-CB 3.41Å; R374-L378 PolarHBondContact O-N 3.5Å; R374-L525 HydrophobicContact CB-CB 4.13Å; R374-L525 HydrophobicContact CB-CD1 4.36Å
375F83.3Confident79.2Confident7 Ų726.1 Ų26.13%0.03114%0.14CC..Hα-helixtrans-58.4-45.1176-179.5-102.1000111.6S371 W372 L378 V379 A459 F462 L525S371-F375 WeakPolarHBondContact O-CB 3.39Å; S371-F375 PolarHBondContact O-N 3.38Å; W372-F375 HydrophobicContact CE3-CD1 4.28Å; W372-F375 HydrophobicContact CZ3-CD1 4.23Å; W372-F375 PolarHBondContact O-N 3.22Å; F375-L378 WeakPolarHBondContact O-CB 3.49Å; F375-L378 PolarHBondContact O-N 3.26Å; F375-V379 HydrophobicContact CD1-CG2 4.27Å; F375-V379 HydrophobicContact CD2-CG2 4.35Å; F375-V379 HydrophobicContact CE1-CG2 3.88Å; F375-V379 HydrophobicContact CE2-CG2 3.97Å; F375-V379 HydrophobicContact CG-CG2 4.5Å; F375-V379 HydrophobicContact CZ-CG2 3.72Å; F375-V379 WeakPolarHBondContact O-CG2 3.34Å; F375-V379 PolarHBondContact O-N 3.41Å; F375-A459 HydrophobicContact CE1-CB 3.96Å; F375-A459 HydrophobicContact CZ-CB 4.32Å; F375-F462 AromaticContact CE1-CD2 3.92Å; F375-F462 HydrophobicContact CE1-CD2 3.92Å; F375-F462 HydrophobicContact CE1-CE2 4.45Å; F375-F462 AromaticContact CZ-CD2 3.98Å; F375-F462 HydrophobicContact CZ-CD2 3.98Å; F375-F462 HydrophobicContact CZ-CE2 4.08Å; F375-L525 HydrophobicContact CB-CD1 4.24Å; F375-L525 HydrophobicContact CB-CD2 4.26Å; F375-L525 HydrophobicContact CD2-CD2 4.11Å
376V84.1Confident79.6Confident12 Ų1225 Ų257%0.07314%0.14CC..Hα-helixtrans-61-46.2174.7166.80000112W372 A373 R374 L378 V379 N380 L470 F479W372-V376 WeakPolarHBondContact O-CB 3.43Å; W372-V376 VanDerWaalsContact O-CG2 3.27Å; W372-V376 WeakPolarHBondContact O-CG2 3.38Å; W372-V376 PolarHBondContact O-N 2.94Å; A373-V376 PolarHBondContact O-N 2.92Å; R374-V376 VanDerWaalsContact C-N 3.33Å; R374-V376 PolarHBondContact O-N 3.4Å; V376-L378 VanDerWaalsContact C-N 3.32Å; V376-L378 PolarHBondContact O-N 3.31Å; V376-V379 PolarHBondContact O-N 3.49Å; V376-N380 WeakPolarHBondContact CG1-ND2 3.4Å; V376-N380 VanDerWaalsContact O-CB 3.31Å; V376-N380 WeakPolarHBondContact O-CB 3.24Å; V376-N380 VanDerWaalsContact O-CG 3.28Å; V376-N380 PolarHBondContact O-N 3.45Å; V376-N380 PolarHBondContact O-ND2 2.89Å; V376-N380 VanDerWaalsContact O-ND2 3.13Å; V376-L470 HydrophobicContact CG2-CD2 3.15Å; V376-L470 HydrophobicContact CG2-CG 4.47Å; V376-F479 HydrophobicContact CG1-CB 3.94Å; V376-F479 WeakPolarHBondContact CG1-O 3.26Å; V376-F479 HydrophobicContact CG2-CB 4.3Å
377S80.9Confident80.3Confident38 Ų3826.5 Ų26.527%0.26614%0.143SC..Hα-helixtrans-56.8-49.3176.8-173.60000110.7A373 R374 N380 L381A373-S377 WeakPolarHBondContact O-CB 3.22Å; A373-S377 PolarHBondContact O-N 3.4Å; R374-S377 WeakPolarHBondContact O-CB 3.44Å; R374-S377 PolarHBondContact O-N 2.99Å; S377-N380 PolarHBondContact O-N 3.43Å; S377-L381 WeakPolarHBondContact O-CG 3.37Å; S377-L381 PolarHBondContact O-N 3.18Å
378L83.9Confident81.1Confident0 Ų025.7 Ų25.70%014%0.138CC..Hα-helixtrans-59.2-53177.8176.8115.2000112.5L350 R374 F375 V376 N380 L381 L382 L528 L532L350-L378 HydrophobicContact CD2-CD2 3.2Å; L350-L378 HydrophobicContact CD2-CG 4.47Å; R374-L378 WeakPolarHBondContact O-CB 3.41Å; R374-L378 PolarHBondContact O-N 3.5Å; F375-L378 WeakPolarHBondContact O-CB 3.49Å; F375-L378 PolarHBondContact O-N 3.26Å; V376-L378 VanDerWaalsContact C-N 3.32Å; V376-L378 PolarHBondContact O-N 3.31Å; L378-N380 PolarHBondContact O-N 3.3Å; L378-L381 WeakPolarHBondContact O-CA 3.31Å; L378-L381 WeakPolarHBondContact O-CB 3.34Å; L378-L381 PolarHBondContact O-N 3.31Å; L378-L382 PolarHBondContact O-N 2.91Å; L378-L382 VanDerWaalsContact O-N 3.15Å; L378-L528 HydrophobicContact CD1-CB 3.21Å; L378-L528 HydrophobicContact CD1-CD1 3.89Å; L378-L528 HydrophobicContact CD1-CG 4.1Å; L378-L532 HydrophobicContact CD1-CD1 3.9Å; L378-L532 HydrophobicContact CG-CD1 4.3Å
379V86.1Confident82Confident0 Ų027.7 Ų27.70%015%0.152CC..Hα-helixtrans-62.3-33.8-178174.80000111.1F375 V376 L381 L382 R456 A459 F479F375-V379 HydrophobicContact CD1-CG2 4.27Å; F375-V379 HydrophobicContact CD2-CG2 4.35Å; F375-V379 HydrophobicContact CE1-CG2 3.88Å; F375-V379 HydrophobicContact CE2-CG2 3.97Å; F375-V379 HydrophobicContact CG-CG2 4.5Å; F375-V379 HydrophobicContact CZ-CG2 3.72Å; F375-V379 WeakPolarHBondContact O-CG2 3.34Å; F375-V379 PolarHBondContact O-N 3.41Å; V376-V379 PolarHBondContact O-N 3.49Å; V379-L381 VanDerWaalsContact C-N 3.29Å; V379-L381 PolarHBondContact O-N 3.03Å; V379-L382 WeakPolarHBondContact O-CB 3.24Å; V379-L382 PolarHBondContact O-N 3.34Å; V379-R456 PolarHBondContact O-NH1 3.46Å; V379-A459 HydrophobicContact CG1-CB 3.85Å; V379-A459 HydrophobicContact CG2-CB 4.24Å; V379-F479 HydrophobicContact CB-CD2 4.42Å; V379-F479 HydrophobicContact CG1-CD2 3.65Å; V379-F479 HydrophobicContact CG1-CE2 3.43Å; V379-F479 VanDerWaalsContact CG1-CE2 3.43Å; V379-F479 HydrophobicContact CG1-CZ 4.24Å
380N85.8Confident82.6Confident46 Ų4628.8 Ų28.825%0.24615%0.152CC..Hα-helixtrans-71.3-20.4172.9-75.5-34000113.7V376 S377 L378 K478 F479V376-N380 WeakPolarHBondContact CG1-ND2 3.4Å; V376-N380 VanDerWaalsContact O-CB 3.31Å; V376-N380 WeakPolarHBondContact O-CB 3.24Å; V376-N380 VanDerWaalsContact O-CG 3.28Å; V376-N380 PolarHBondContact O-N 3.45Å; V376-N380 PolarHBondContact O-ND2 2.89Å; V376-N380 VanDerWaalsContact O-ND2 3.13Å; S377-N380 PolarHBondContact O-N 3.43Å; L378-N380 PolarHBondContact O-N 3.3Å; N380-K478 WeakPolarHBondContact OD1-CA 3.42Å; N380-K478 WeakPolarHBondContact OD1-CB 3.15Å; N380-F479 PolarHBondContact ND2-O 3.17Å; N380-F479 PolarHBondContact OD1-N 3.3Å
381L81.3Confident83.3Confident20 Ų2028.7 Ų28.711%0.10515%0.151CC..Hα-helixtrans-82.2-20.8171.4-69.4168.8000112.4K337 S377 L378 V379 L532 K536K337-L381 WeakPolarHBondContact CE-O 3.43Å; K337-L381 PolarHBondContact NZ-O 3Å; S377-L381 WeakPolarHBondContact O-CG 3.37Å; S377-L381 PolarHBondContact O-N 3.18Å; L378-L381 WeakPolarHBondContact O-CA 3.31Å; L378-L381 WeakPolarHBondContact O-CB 3.34Å; L378-L381 PolarHBondContact O-N 3.31Å; V379-L381 VanDerWaalsContact C-N 3.29Å; V379-L381 PolarHBondContact O-N 3.03Å; L381-L532 HydrophobicContact CB-CB 4.27Å; L381-L532 HydrophobicContact CB-CD1 3.94Å; L381-L532 HydrophobicContact CD1-CB 3.69Å; L381-L532 HydrophobicContact CD1-CD1 4.3Å; L381-K536 HydrophobicContact CD2-CD 3.93Å
382L85.8Confident84Confident0 Ų030.6 Ų30.60%016%0.162CC..SBendtrans-70.8160.5174-60.6-179.6000111.9K337 L341 L347 L378 V379 T384 I452 L455 L532K337-L382 PolarHBondContact NZ-O 3.33Å; L341-L382 HydrophobicContact CD1-CD2 4.29Å; L341-L382 HydrophobicContact CD2-CD2 3.94Å; L347-L382 HydrophobicContact CD2-CD2 4.26Å; L378-L382 PolarHBondContact O-N 2.91Å; L378-L382 VanDerWaalsContact O-N 3.15Å; V379-L382 WeakPolarHBondContact O-CB 3.24Å; V379-L382 PolarHBondContact O-N 3.34Å; L382-T384 PolarHBondContact O-N 3.48Å; L382-I452 HydrophobicContact CB-CG2 4.2Å; L382-I452 HydrophobicContact CD1-CG2 4.47Å; L382-L455 HydrophobicContact CD1-CB 3.89Å; L382-L455 HydrophobicContact CD1-CD1 3.86Å; L382-L532 HydrophobicContact CD2-CD1 4.44Å
383P85.4Confident84.4Confident0 Ų034 Ų340%019%0.192CC..PPolyproline II helixtrans-52.8138.4170.2-27.335.5000111.8V334 K337 L341 E387 L388 I452 R456V334-P383 HydrophobicContact CG1-CB 4.3Å; V334-P383 HydrophobicContact CG1-CG 4.47Å; K337-P383 HydrophobicContact CD-CG 4.24Å; K337-P383 HydrophobicContact CG-CG 4.46Å; L341-P383 HydrophobicContact CD1-CG 3.97Å; P383-E387 VanDerWaalsContact CA-OE2 3.23Å; P383-E387 WeakPolarHBondContact CA-OE2 3.4Å; P383-E387 HydrophobicContact CB-CB 4.2Å; P383-L388 HydrophobicContact CB-CD2 3.96Å; P383-L388 HydrophobicContact CB-CG 4.06Å; P383-I452 HydrophobicContact CG-CD1 4.13Å; P383-R456 VanDerWaalsContact O-CD 3.31Å; P383-R456 WeakPolarHBondContact O-CD 3.34Å; P383-R456 PolarHBondContact O-NH1 2.64Å
384T84.9Confident84.6Confident45 Ų4537.3 Ų37.328%0.27620%0.197SC..PPolyproline II helixtrans-73.1164.3173.3640000111.6L382 F386 E387 L388L382-T384 PolarHBondContact O-N 3.48Å; T384-F386 PolarHBondContact O-N 2.84Å; T384-E387 PolarHBondContact N-OE2 3.22Å; T384-E387 WeakPolarHBondContact O-CB 3.32Å; T384-E387 PolarHBondContact O-N 3.35Å; T384-E387 VanDerWaalsContact O-N 3.1Å; T384-E387 WeakPolarHBondContact OG1-CB 3.25Å; T384-E387 VanDerWaalsContact OG1-CG 3.27Å; T384-E387 WeakPolarHBondContact OG1-CG 3.48Å; T384-E387 PolarHBondContact OG1-N 3.26Å; T384-E387 PolarHBondContact OG1-OE2 2.85Å; T384-L388 WeakPolarHBondContact O-CG 3.45Å; T384-L388 PolarHBondContact O-N 3.37Å
385E87.6Confident85.1Confident22 Ų2235.6 Ų35.610%0.10319%0.194CC..Hα-helixtrans-58.3-38.7176.2-57-167.3-161.300112.2L388 S389 M408 L410 H460E385-L388 PolarHBondContact O-N 2.84Å; E385-S389 WeakPolarHBondContact O-CB 3.37Å; E385-S389 PolarHBondContact O-N 3.06Å; E385-M408 HydrophobicContact CB-CE 3.61Å; E385-M408 HydrophobicContact CB-SD 4.24Å; E385-L410 HydrophobicContact CG-CB 4.28Å; E385-L410 HydrophobicContact CG-CD1 3.8Å; E385-L410 HydrophobicContact CG-CG 3.96Å; E385-L410 PolarHBondContact OE2-N 2.59Å; E385-H460 IonicContact OE1-CD2 3.71Å; E385-H460 IonicContact OE1-CE1 3.54Å; E385-H460 IonicContact OE1-NE2 3.01Å; E385-H460 PolarHBondContact OE1-NE2 3.3Å
386F84.7Confident85.3Confident128 Ų12844 Ų4456%0.56123%0.231SC*.Hα-helixtrans-63-44.6174.2-63.8-76.2000111.9T384 L388 S389 D390 L477T384-F386 PolarHBondContact O-N 2.84Å; F386-L388 VanDerWaalsContact C-N 3.35Å; F386-L388 PolarHBondContact O-N 3.5Å; F386-S389 PolarHBondContact O-N 2.9Å; F386-D390 WeakPolarHBondContact O-CB 3.1Å; F386-D390 PolarHBondContact O-N 3.2Å; F386-L477 HydrophobicContact CD2-CD1 4.45Å; F386-L477 HydrophobicContact CE2-CD1 3.81Å
387E84.8Confident85.4Confident55 Ų5549.9 Ų49.926%0.25726%0.255SS..Hα-helixtrans-63.7-38.6176.4-75.3176.4136.600112.1V334 P383 T384 D390 I391V334-E387 HydrophobicContact CG1-CB 3.85Å; V334-E387 HydrophobicContact CG1-CG 4.41Å; V334-E387 HydrophobicContact CG2-CB 4.15Å; V334-E387 HydrophobicContact CG2-CG 3.83Å; V334-E387 WeakPolarHBondContact CG2-OE1 3.47Å; P383-E387 VanDerWaalsContact CA-OE2 3.23Å; P383-E387 WeakPolarHBondContact CA-OE2 3.4Å; P383-E387 HydrophobicContact CB-CB 4.2Å; T384-E387 PolarHBondContact N-OE2 3.22Å; T384-E387 WeakPolarHBondContact O-CB 3.32Å; T384-E387 PolarHBondContact O-N 3.35Å; T384-E387 VanDerWaalsContact O-N 3.1Å; T384-E387 WeakPolarHBondContact OG1-CB 3.25Å; T384-E387 VanDerWaalsContact OG1-CG 3.27Å; T384-E387 WeakPolarHBondContact OG1-CG 3.48Å; T384-E387 PolarHBondContact OG1-N 3.26Å; T384-E387 PolarHBondContact OG1-OE2 2.85Å; E387-D390 PolarHBondContact O-N 2.84Å; E387-I391 VanDerWaalsContact O-CG1 3.31Å; E387-I391 WeakPolarHBondContact O-CG1 3.44Å; E387-I391 PolarHBondContact O-N 2.8Å
388L88.8Confident85.7Confident0 Ų048.2 Ų48.20%024%0.243CC..Hα-helixtrans-66.2-42.8175-69.1169.8000111.6P383 T384 E385 F386 I391 N392 F406 L410 F449 I452P383-L388 HydrophobicContact CB-CD2 3.96Å; P383-L388 HydrophobicContact CB-CG 4.06Å; T384-L388 WeakPolarHBondContact O-CG 3.45Å; T384-L388 PolarHBondContact O-N 3.37Å; E385-L388 PolarHBondContact O-N 2.84Å; F386-L388 VanDerWaalsContact C-N 3.35Å; F386-L388 PolarHBondContact O-N 3.5Å; L388-I391 PolarHBondContact O-N 3.03Å; L388-N392 WeakPolarHBondContact O-CB 3.45Å; L388-N392 PolarHBondContact O-N 2.85Å; L388-F406 HydrophobicContact CB-CE2 4.24Å; L388-F406 HydrophobicContact CB-CZ 4.09Å; L388-L410 HydrophobicContact CD1-CD1 4.06Å; L388-F449 HydrophobicContact CB-CE2 3.97Å; L388-F449 HydrophobicContact CB-CZ 3.83Å; L388-F449 HydrophobicContact CD2-CD2 3.74Å; L388-F449 HydrophobicContact CD2-CE1 4.49Å; L388-F449 HydrophobicContact CD2-CE2 3.49Å; L388-F449 VanDerWaalsContact CD2-CE2 3.49Å; L388-F449 HydrophobicContact CD2-CG 4.37Å; L388-F449 HydrophobicContact CD2-CZ 3.9Å; L388-F449 HydrophobicContact CG-CE2 4.33Å; L388-F449 HydrophobicContact CG-CZ 4.41Å; L388-F449 WeakPolarHBondContact O-CE2 3.29Å; L388-I452 HydrophobicContact CD1-CG2 4.09Å; L388-I452 HydrophobicContact CD2-CG2 4.16Å
389S88Confident85.9Confident49 Ų4949.4 Ų49.434%0.34325%0.253SS..Hα-helixtrans-61.5-43.1175.1-168.10000111.8E385 F386 I391 N392 A393E385-S389 WeakPolarHBondContact O-CB 3.37Å; E385-S389 PolarHBondContact O-N 3.06Å; F386-S389 PolarHBondContact O-N 2.9Å; S389-I391 PolarHBondContact O-N 3.33Å; S389-N392 PolarHBondContact O-N 2.81Å; S389-A393 WeakPolarHBondContact O-CB 3.44Å; S389-A393 PolarHBondContact O-N 2.78Å
390D84.2Confident86.1Confident58 Ų5855.4 Ų55.431%0.3128%0.279SS..Hα-helixtrans-61.2-43.4174.3-99.4-38.4000112.3F386 E387 A393 R394F386-D390 WeakPolarHBondContact O-CB 3.1Å; F386-D390 PolarHBondContact O-N 3.2Å; E387-D390 PolarHBondContact O-N 2.84Å; D390-A393 PolarHBondContact O-N 3.32Å; D390-R394 VanDerWaalsContact O-CB 3.31Å; D390-R394 WeakPolarHBondContact O-CB 3.31Å; D390-R394 WeakPolarHBondContact O-CD 3.4Å; D390-R394 VanDerWaalsContact O-CG 3.26Å; D390-R394 WeakPolarHBondContact O-CG 3.38Å; D390-R394 PolarHBondContact O-N 2.81Å; D390-R394 IonicContact OD1-CZ 3.64Å; D390-R394 IonicContact OD1-NE 3.64Å; D390-R394 PolarHBondContact OD1-NE 2.86Å; D390-R394 IonicContact OD1-NH2 3.83Å; D390-R394 PolarHBondContact OD1-NH2 3.48Å; D390-R394 IonicContact OD2-NH2 2.98Å
391I85.3Confident86.1Confident0 Ų055.3 Ų55.30%028%0.277CS..Hα-helixtrans-60.4-47.8173.9-68.8163.6000110.2V334 L338 E387 L388 S389 A393 R394 N395 I398 F449V334-I391 HydrophobicContact CB-CD1 4.33Å; V334-I391 HydrophobicContact CB-CG1 4.38Å; V334-I391 HydrophobicContact CG1-CD1 3.28Å; V334-I391 HydrophobicContact CG1-CG1 3.75Å; L338-I391 HydrophobicContact CD2-CD1 4.26Å; L338-I391 HydrophobicContact CD2-CG2 4.45Å; E387-I391 VanDerWaalsContact O-CG1 3.31Å; E387-I391 WeakPolarHBondContact O-CG1 3.44Å; E387-I391 PolarHBondContact O-N 2.8Å; L388-I391 PolarHBondContact O-N 3.03Å; S389-I391 PolarHBondContact O-N 3.33Å; I391-A393 VanDerWaalsContact C-N 3.28Å; I391-A393 PolarHBondContact O-N 3.17Å; I391-R394 PolarHBondContact O-N 2.73Å; I391-N395 HydrophobicContact CG2-CB 4.11Å; I391-N395 VanDerWaalsContact O-CB 3.24Å; I391-N395 WeakPolarHBondContact O-CB 3.28Å; I391-N395 PolarHBondContact O-N 3.04Å; I391-I398 HydrophobicContact CG2-CD1 3.86Å; I391-F449 HydrophobicContact CB-CE2 4.12Å; I391-F449 HydrophobicContact CD1-CE2 4.44Å; I391-F449 HydrophobicContact CG2-CD2 4.22Å; I391-F449 HydrophobicContact CG2-CE2 4.03Å
392N87.6Confident86.4Confident43 Ų4354.4 Ų54.423%0.2327%0.272CS..Hα-helixtrans-62.2-36.4-179.4-174.645.4000111.7L388 S389 A399 I402 F406 F449L388-N392 WeakPolarHBondContact O-CB 3.45Å; L388-N392 PolarHBondContact O-N 2.85Å; S389-N392 PolarHBondContact O-N 2.81Å; N392-A399 WeakPolarHBondContact O-CB 3.49Å; N392-I402 HydrophobicContact CB-CD1 4.43Å; N392-I402 WeakPolarHBondContact OD1-CD1 3.19Å; N392-F406 HydrophobicContact CB-CD1 4.1Å; N392-F406 HydrophobicContact CB-CE1 4.12Å; N392-F449 HydrophobicContact CB-CZ 4.41Å
393A87.1Confident86.5Confident80 Ų8063.7 Ų63.766%0.66131%0.307SS*.Hα-helixtrans-72-36.617700000113.1S389 D390 I391S389-A393 WeakPolarHBondContact O-CB 3.44Å; S389-A393 PolarHBondContact O-N 2.78Å; D390-A393 PolarHBondContact O-N 3.32Å; I391-A393 VanDerWaalsContact C-N 3.28Å; I391-A393 PolarHBondContact O-N 3.17Å
394R82Confident86.5Confident101 Ų10165.8 Ų65.838%0.38133%0.329SS..Hα-helixtrans-101.9-30.3-168-62.5169.4-166.5-129.47.8114A327 C331 D390 I391 K396A327-R394 VanDerWaalsContact C-NH1 3.26Å; A327-R394 PolarHBondContact O-NH1 3.4Å; C331-R394 VanDerWaalsContact SG-CB 3.55Å; C331-R394 WeakPolarHBondContact SG-CD 3.17Å; D390-R394 VanDerWaalsContact O-CB 3.31Å; D390-R394 WeakPolarHBondContact O-CB 3.31Å; D390-R394 WeakPolarHBondContact O-CD 3.4Å; D390-R394 VanDerWaalsContact O-CG 3.26Å; D390-R394 WeakPolarHBondContact O-CG 3.38Å; D390-R394 PolarHBondContact O-N 2.81Å; D390-R394 IonicContact OD1-CZ 3.64Å; D390-R394 IonicContact OD1-NE 3.64Å; D390-R394 PolarHBondContact OD1-NE 2.86Å; D390-R394 IonicContact OD1-NH2 3.83Å; D390-R394 PolarHBondContact OD1-NH2 3.48Å; D390-R394 IonicContact OD2-NH2 2.98Å; I391-R394 PolarHBondContact O-N 2.73Å; R394-K396 PolarHBondContact O-N 3.05Å
395N85.5Confident86.5Confident43 Ų4364.3 Ų64.323%0.2332%0.32CS..  trans-91.989.4-180-169.6-34.8000110.7I391 K397 I398 A399I391-N395 HydrophobicContact CG2-CB 4.11Å; I391-N395 VanDerWaalsContact O-CB 3.24Å; I391-N395 WeakPolarHBondContact O-CB 3.28Å; I391-N395 PolarHBondContact O-N 3.04Å; N395-K397 PolarHBondContact O-N 2.91Å; N395-K397 VanDerWaalsContact O-N 3.08Å; N395-K397 PolarHBondContact OD1-N 3.3Å; N395-I398 HydrophobicContact CB-CB 4.25Å; N395-I398 HydrophobicContact CB-CD1 4.28Å; N395-I398 HydrophobicContact CB-CG1 4.4Å; N395-I398 VanDerWaalsContact ND2-CD1 3.34Å; N395-I398 WeakPolarHBondContact ND2-CD1 3.41Å; N395-I398 PolarHBondContact O-N 2.66Å; N395-I398 PolarHBondContact OD1-N 3.14Å; N395-A399 VanDerWaalsContact O-CB 3.31Å; N395-A399 WeakPolarHBondContact O-CB 3.39Å; N395-A399 PolarHBondContact O-N 3.19Å
396K86.7Confident86.6Confident185 Ų18564.2 Ų64.280%0.80432%0.319SS*.Hα-helixtrans-54-30.9-178.3-64.7-175.1-179.7-179.50114.1R394 K400R394-K396 PolarHBondContact O-N 3.05Å; K396-K400 VanDerWaalsContact O-CB 3.31Å; K396-K400 WeakPolarHBondContact O-CB 3.3Å; K396-K400 PolarHBondContact O-N 2.75Å; K396-K400 VanDerWaalsContact O-N 3.12Å
397K87.8Confident86.9Confident134 Ų13462.4 Ų62.458%0.58331%0.309SS*.Hα-helixtrans-69.2-54.8179.1-175.9-177.2176.8-173.40110.2N395 A399 K400 E401N395-K397 PolarHBondContact O-N 2.91Å; N395-K397 VanDerWaalsContact O-N 3.08Å; N395-K397 PolarHBondContact OD1-N 3.3Å; K397-A399 PolarHBondContact O-N 3.37Å; K397-K400 PolarHBondContact O-N 3.3Å; K397-E401 WeakPolarHBondContact CE-OE1 3.37Å; K397-E401 PolarHBondContact O-N 3.49Å
398I86.6Confident87Confident4 Ų463 Ų632%0.02131%0.313CS..Hα-helixtrans-60.3-48.7177.6-64.2176.8000109.7L338 I391 N395 K400 E401 I402 T445 F449L338-I398 HydrophobicContact CD2-CD1 3.69Å; I391-I398 HydrophobicContact CG2-CD1 3.86Å; N395-I398 HydrophobicContact CB-CB 4.25Å; N395-I398 HydrophobicContact CB-CD1 4.28Å; N395-I398 HydrophobicContact CB-CG1 4.4Å; N395-I398 VanDerWaalsContact ND2-CD1 3.34Å; N395-I398 WeakPolarHBondContact ND2-CD1 3.41Å; N395-I398 PolarHBondContact O-N 2.66Å; N395-I398 PolarHBondContact OD1-N 3.14Å; I398-K400 PolarHBondContact O-N 3.16Å; I398-K400 VanDerWaalsContact O-N 3.13Å; I398-E401 WeakPolarHBondContact O-CA 3.34Å; I398-E401 PolarHBondContact O-N 3.04Å; I398-I402 HydrophobicContact CG2-CD1 3.84Å; I398-I402 HydrophobicContact CG2-CG1 4.18Å; I398-I402 HydrophobicContact CG2-CG2 4.33Å; I398-I402 WeakPolarHBondContact O-CG1 3.43Å; I398-I402 PolarHBondContact O-N 3.07Å; I398-T445 HydrophobicContact CD1-CG2 3.82Å; I398-F449 HydrophobicContact CG2-CD2 4.34Å
399A88.4Confident87.1Confident24 Ų2465.5 Ų65.520%0.19833%0.329CS..Hα-helixtrans-56.4-32.1179.800000113.8N392 N395 K397 R403N392-A399 WeakPolarHBondContact O-CB 3.49Å; N395-A399 VanDerWaalsContact O-CB 3.31Å; N395-A399 WeakPolarHBondContact O-CB 3.39Å; N395-A399 PolarHBondContact O-N 3.19Å; K397-A399 PolarHBondContact O-N 3.37Å; A399-R403 WeakPolarHBondContact O-CB 3.24Å; A399-R403 PolarHBondContact O-N 2.67Å
400K89.1Confident87.1Confident127 Ų12763.2 Ų63.255%0.55231%0.313SS*.Hα-helixtrans-73.9-36.6175.2-176.5-178177.5-176.40112K396 K397 I398K396-K400 VanDerWaalsContact O-CB 3.31Å; K396-K400 WeakPolarHBondContact O-CB 3.3Å; K396-K400 PolarHBondContact O-N 2.75Å; K396-K400 VanDerWaalsContact O-N 3.12Å; K397-K400 PolarHBondContact O-N 3.3Å; I398-K400 PolarHBondContact O-N 3.16Å; I398-K400 VanDerWaalsContact O-N 3.13Å
401E87Confident87.2Confident44 Ų4462 Ų6221%0.20631%0.309CS..Hα-helixtrans-75.9-38-179.8-68.5175.7-153.500112K397 I398 S443 A446K397-E401 WeakPolarHBondContact CE-OE1 3.37Å; K397-E401 PolarHBondContact O-N 3.49Å; I398-E401 WeakPolarHBondContact O-CA 3.34Å; I398-E401 PolarHBondContact O-N 3.04Å; E401-S443 WeakPolarHBondContact OE2-CB 3.42Å; E401-S443 PolarHBondContact OE2-N 3.06Å; E401-S443 PolarHBondContact OE2-OG 3.42Å; E401-A446 HydrophobicContact CB-CB 4.14Å; E401-A446 VanDerWaalsContact OE2-CB 3.24Å; E401-A446 WeakPolarHBondContact OE2-CB 3.34Å
402I87.7Confident87.3Confident1 Ų168.1 Ų68.11%0.00534%0.337CS..SBendtrans-9912.4-178.272.6174000114.4N392 I398 G404 L405 F406 M442 A446 F449 L450N392-I402 HydrophobicContact CB-CD1 4.43Å; N392-I402 WeakPolarHBondContact OD1-CD1 3.19Å; I398-I402 HydrophobicContact CG2-CD1 3.84Å; I398-I402 HydrophobicContact CG2-CG1 4.18Å; I398-I402 HydrophobicContact CG2-CG2 4.33Å; I398-I402 WeakPolarHBondContact O-CG1 3.43Å; I398-I402 PolarHBondContact O-N 3.07Å; I402-G404 PolarHBondContact O-N 2.79Å; I402-G404 VanDerWaalsContact O-N 3.13Å; I402-L405 HydrophobicContact CB-CB 4.45Å; I402-L405 WeakPolarHBondContact O-CB 3.28Å; I402-L405 PolarHBondContact O-N 3.24Å; I402-F406 HydrophobicContact CD1-CB 4.04Å; I402-M442 HydrophobicContact CG2-CE 3.93Å; I402-A446 HydrophobicContact CG2-CB 4Å; I402-F449 HydrophobicContact CD1-CD1 3.62Å; I402-F449 HydrophobicContact CD1-CE1 3.33Å; I402-F449 HydrophobicContact CD1-CE2 4.34Å; I402-F449 HydrophobicContact CD1-CG 4.27Å; I402-F449 HydrophobicContact CD1-CZ 3.73Å; I402-L450 HydrophobicContact CG2-CG 4.5Å
403R87.2Confident87.4Confident194 Ų19466.2 Ų66.273%0.73233%0.327SS*.THydrogen-bonded Turntrans-57.2120.8-176.3-174.5-176.8-63.1-164.8-3.1110.8A399 L405A399-R403 WeakPolarHBondContact O-CB 3.24Å; A399-R403 PolarHBondContact O-N 2.67Å; R403-L405 PolarHBondContact O-N 2.82Å
404G84.9Confident87.3Confident45 Ų4566.6 Ų66.646%0.46432%0.315SS..THydrogen-bonded Turntrans80.5-0.3-178.900000114.5I402I402-G404 PolarHBondContact O-N 2.79Å; I402-G404 VanDerWaalsContact O-N 3.13Å
405L86.5Confident87.5Confident14 Ų1462.4 Ų62.47%0.07330%0.3CS..THydrogen-bonded Turntrans-101.4-7178.1-56.1-178.1000113.1I402 R403 W413 E416 V417 I438 M442 L450I402-L405 HydrophobicContact CB-CB 4.45Å; I402-L405 WeakPolarHBondContact O-CB 3.28Å; I402-L405 PolarHBondContact O-N 3.24Å; R403-L405 PolarHBondContact O-N 2.82Å; L405-W413 PolarHBondContact O-NE1 3.18Å; L405-E416 HydrophobicContact CD2-CB 4.2Å; L405-V417 HydrophobicContact CD1-CG2 3.73Å; L405-V417 HydrophobicContact CD2-CG2 3.48Å; L405-V417 VanDerWaalsContact CD2-CG2 3.48Å; L405-V417 HydrophobicContact CG-CG2 4.21Å; L405-I438 HydrophobicContact CD1-CD1 3.99Å; L405-M442 HydrophobicContact CD1-SD 4.45Å; L405-L450 HydrophobicContact CB-CD2 4.41Å; L405-L450 HydrophobicContact CD1-CD1 4.37Å
406F89.8Confident87.2Confident20 Ų2062.2 Ų62.29%0.08830%0.298CS..  trans-133.5131.6-178.4171.3-99.6000110L388 N392 I402 M408 L410 F449L388-F406 HydrophobicContact CB-CE2 4.24Å; L388-F406 HydrophobicContact CB-CZ 4.09Å; N392-F406 HydrophobicContact CB-CD1 4.1Å; N392-F406 HydrophobicContact CB-CE1 4.12Å; I402-F406 HydrophobicContact CD1-CB 4.04Å; F406-M408 HydrophobicContact CZ-CG 3.99Å; F406-L410 HydrophobicContact CD2-CD2 4.21Å; F406-L410 HydrophobicContact CE2-CD2 3.83Å; F406-F449 HydrophobicContact CB-CE1 4.23Å; F406-F449 HydrophobicContact CD1-CE1 4.5Å; F406-F449 HydrophobicContact CD1-CZ 4.41Å; F406-F449 AromaticContact CD2-CE1 3.65Å; F406-F449 HydrophobicContact CD2-CE1 3.65Å; F406-F449 HydrophobicContact CD2-CZ 4.06Å; F406-F449 HydrophobicContact CE1-CZ 4.46Å; F406-F449 HydrophobicContact CE2-CE1 4.09Å; F406-F449 HydrophobicContact CE2-CZ 4.09Å; F406-F449 AromaticContact CG-CE1 3.87Å; F406-F449 HydrophobicContact CG-CE1 3.87Å; F406-F449 HydrophobicContact CG-CZ 4.2Å; F406-F449 HydrophobicContact CZ-CZ 4.3Å
407Y90.4Very high86.8Confident89 Ų8953.9 Ų53.935%0.34926%0.262SS..  trans-149.8162171.160.3-91.1000109.4E412 W413 E414Y407-E412 WeakPolarHBondContact CE2-O 3.14Å; Y407-E412 PolarHBondContact OH-O 2.91Å; Y407-W413 AromaticContact CD1-CD1 3.66Å; Y407-W413 AromaticContact CE1-CD1 3.61Å; Y407-W413 HydrophobicContact CE1-CG 4.45Å; Y407-W413 HydrophobicContact CE2-CB 4.24Å; Y407-W413 WeakPolarHBondContact OH-CA 3.19Å; Y407-E414 PolarHBondContact OH-N 3.18Å; Y407-E414 VanDerWaalsContact OH-N 3.09Å
408M87.5Confident86.3Confident69 Ų6947.8 Ų47.834%0.3424%0.236SC..SBendtrans-112.6153.6175.1-75.6-175.964.300109.7E385 F406E385-M408 HydrophobicContact CB-CE 3.61Å; E385-M408 HydrophobicContact CB-SD 4.24Å; F406-M408 HydrophobicContact CZ-CG 3.99Å
409P89.1Confident86.2Confident52 Ų5247.7 Ų47.734%0.33824%0.236SC..  cis-75.5148.90.132-35.4000112.9S411 E412 W413P409-S411 PolarHBondContact O-N 3.14Å; P409-E412 HydrophobicContact CG-CB 4.27Å; P409-E412 HydrophobicContact CG-CG 4.02Å; P409-E412 PolarHBondContact O-N 3.49Å; P409-E412 VanDerWaalsContact O-N 3.11Å; P409-W413 PolarHBondContact O-N 3.22Å
410L89.2Confident85.8Confident0 Ų050.2 Ų50.20%025%0.251CS..G310 helixtrans-65.7-19.6179.9-73-174.2000113.5E385 L388 F406 E412 W413 C453 R456E385-L410 HydrophobicContact CG-CB 4.28Å; E385-L410 HydrophobicContact CG-CD1 3.8Å; E385-L410 HydrophobicContact CG-CG 3.96Å; E385-L410 PolarHBondContact OE2-N 2.59Å; L388-L410 HydrophobicContact CD1-CD1 4.06Å; F406-L410 HydrophobicContact CD2-CD2 4.21Å; F406-L410 HydrophobicContact CE2-CD2 3.83Å; L410-E412 PolarHBondContact O-N 2.79Å; L410-W413 HydrophobicContact CB-CB 4.46Å; L410-W413 HydrophobicContact CD2-CB 3.75Å; L410-W413 HydrophobicContact CD2-CD2 4.16Å; L410-W413 HydrophobicContact CD2-CG 3.82Å; L410-W413 WeakPolarHBondContact O-CB 3.47Å; L410-W413 PolarHBondContact O-N 3.13Å; L410-W413 VanDerWaalsContact O-N 3.13Å; L410-C453 HydrophobicContact CD1-CB 4.39Å; L410-C453 HydrophobicContact CD2-CB 4.11Å; L410-R456 HydrophobicContact CD1-CB 3.74Å; L410-R456 HydrophobicContact CD1-CG 4.39Å
411S86.9Confident85.6Confident34 Ų3444.4 Ų44.424%0.23823%0.225CC..G310 helixtrans-62.9-18.3173.557.80000114.4P409 R464P409-S411 PolarHBondContact O-N 3.14Å; S411-R464 PolarHBondContact O-NH2 2.65Å; S411-R464 VanDerWaalsContact O-NH2 3.12Å
412E86.3Confident85.4Confident127 Ų12742.4 Ų42.459%0.59322%0.216SC*.G310 helixtrans-114.3-0.3177.1-62.6177.4179.700111.6Y407 P409 L410Y407-E412 WeakPolarHBondContact CE2-O 3.14Å; Y407-E412 PolarHBondContact OH-O 2.91Å; P409-E412 HydrophobicContact CG-CB 4.27Å; P409-E412 HydrophobicContact CG-CG 4.02Å; P409-E412 PolarHBondContact O-N 3.49Å; P409-E412 VanDerWaalsContact O-N 3.11Å; L410-E412 PolarHBondContact O-N 2.79Å
413W90.5Very high84.7Confident3 Ų342.8 Ų42.81%0.01122%0.22CC..  trans-76.8128-177.9177.379000111.2L405 Y407 P409 L410 Q415 L450 C453 K457L405-W413 PolarHBondContact O-NE1 3.18Å; Y407-W413 AromaticContact CD1-CD1 3.66Å; Y407-W413 AromaticContact CE1-CD1 3.61Å; Y407-W413 HydrophobicContact CE1-CG 4.45Å; Y407-W413 HydrophobicContact CE2-CB 4.24Å; Y407-W413 WeakPolarHBondContact OH-CA 3.19Å; P409-W413 PolarHBondContact O-N 3.22Å; L410-W413 HydrophobicContact CB-CB 4.46Å; L410-W413 HydrophobicContact CD2-CB 3.75Å; L410-W413 HydrophobicContact CD2-CD2 4.16Å; L410-W413 HydrophobicContact CD2-CG 3.82Å; L410-W413 WeakPolarHBondContact O-CB 3.47Å; L410-W413 PolarHBondContact O-N 3.13Å; L410-W413 VanDerWaalsContact O-N 3.13Å; W413-Q415 HydrophobicContact CH2-CB 3.76Å; W413-Q415 HydrophobicContact CH2-CG 4.05Å; W413-Q415 HydrophobicContact CZ2-CB 4.45Å; W413-Q415 HydrophobicContact CZ3-CB 4.05Å; W413-L450 HydrophobicContact CZ2-CD2 4.09Å; W413-C453 HydrophobicContact CD2-CB 4.43Å; W413-C453 HydrophobicContact CE3-CB 4.13Å; W413-C453 HydrophobicContact CH2-CB 3.97Å; W413-C453 HydrophobicContact CZ2-CB 4.28Å; W413-C453 HydrophobicContact CZ3-CB 3.89Å; W413-K457 HydrophobicContact CE3-CB 4.48Å; W413-K457 HydrophobicContact CE3-CD 4.31Å; W413-K457 VanDerWaalsContact O-CD 3.23Å; W413-K457 WeakPolarHBondContact O-CD 3.35Å; W413-K457 WeakPolarHBondContact O-CE 3.3Å
414E84.7Confident84.1Confident88 Ų8835.9 Ų35.941%0.41120%0.2SC..  trans-106.9141.9173.8-71.2-59.315400112.1Y407 E416 K457Y407-E414 PolarHBondContact OH-N 3.18Å; Y407-E414 VanDerWaalsContact OH-N 3.09Å; E414-E416 PolarHBondContact O-N 3.24Å; E414-E416 VanDerWaalsContact O-N 3.1Å; E414-K457 IonicContact OE1-NZ 3.17Å; E414-K457 PolarHBondContact OE1-NZ 3.49Å; E414-K457 IonicContact OE2-NZ 2.96Å; E414-K457 PolarHBondContact OE2-NZ 3.4Å
415Q85.7Confident83.7Confident14 Ų1433.8 Ų33.87%0.06518%0.179CC..  trans-75.1101.3177-175.4-175.5-11.400109.9W413 V417 D422 L433 C454W413-Q415 HydrophobicContact CH2-CB 3.76Å; W413-Q415 HydrophobicContact CH2-CG 4.05Å; W413-Q415 HydrophobicContact CZ2-CB 4.45Å; W413-Q415 HydrophobicContact CZ3-CB 4.05Å; Q415-V417 VanDerWaalsContact C-N 3.29Å; Q415-V417 VanDerWaalsContact CG-O 3.27Å; Q415-V417 WeakPolarHBondContact CG-O 3.49Å; Q415-V417 PolarHBondContact NE2-O 2.89Å; Q415-V417 PolarHBondContact O-N 3.12Å; Q415-D422 PolarHBondContact NE2-OD2 3.02Å; Q415-L433 HydrophobicContact CB-CD2 4.23Å; Q415-L433 HydrophobicContact CG-CD2 4.03Å; Q415-C454 PolarHBondContact OE1-SG 2.84Å
416E79.6Confident83.2Confident39 Ų3934.3 Ų34.318%0.18218%0.18CC..  trans-845.9179.5-62.2-171.5-175.400114.9L405 E414 H434 R436L405-E416 HydrophobicContact CD2-CB 4.2Å; E414-E416 PolarHBondContact O-N 3.24Å; E414-E416 VanDerWaalsContact O-N 3.1Å; E416-H434 CarbonylContact C-O 3.58Å; E416-H434 HydrophobicContact CB-CB 4.47Å; E416-H434 HydrophobicContact CG-CB 4.46Å; E416-R436 WeakPolarHBondContact OE2-CD 3.31Å; E416-R436 IonicContact OE2-CZ 2.81Å; E416-R436 IonicContact OE2-NE 2.73Å; E416-R436 IonicContact OE2-NH1 3.17Å; E416-R436 PolarHBondContact OE2-NH1 3.23Å
417V78Confident82.3Confident9 Ų934.9 Ų34.96%0.05518%0.184CC..SBendtrans-151129.1-172.8174.80000109.1L405 Q415 L419 I438L405-V417 HydrophobicContact CD1-CG2 3.73Å; L405-V417 HydrophobicContact CD2-CG2 3.48Å; L405-V417 VanDerWaalsContact CD2-CG2 3.48Å; L405-V417 HydrophobicContact CG-CG2 4.21Å; Q415-V417 VanDerWaalsContact C-N 3.29Å; Q415-V417 VanDerWaalsContact CG-O 3.27Å; Q415-V417 WeakPolarHBondContact CG-O 3.49Å; Q415-V417 PolarHBondContact NE2-O 2.89Å; Q415-V417 PolarHBondContact O-N 3.12Å; V417-L419 PolarHBondContact O-N 3.08Å; V417-I438 HydrophobicContact CB-CD1 3.96Å; V417-I438 HydrophobicContact CB-CG1 4.42Å; V417-I438 HydrophobicContact CG1-CD1 3.21Å; V417-I438 HydrophobicContact CG1-CG1 3.83Å; V417-I438 HydrophobicContact CG2-CD1 3.5Å; V417-I438 HydrophobicContact CG2-CG1 3.69Å
418S77.6Confident81.6Confident6 Ų630.8 Ų30.84%0.04217%0.168CC..  trans-68.6127172.6-35.90000111.1L433S418-L433 VanDerWaalsContact OG-CD1 3.32Å; S418-L433 WeakPolarHBondContact OG-CD1 3.33Å
419L83.5Confident81.2Confident2 Ų227.8 Ų27.81%0.0115%0.154CC..  trans-78.2165169.7-54.4-178.9000109.6V417 E421 D422 A423 V447 L450 R451V417-L419 PolarHBondContact O-N 3.08Å; L419-E421 PolarHBondContact O-N 3.27Å; L419-E421 VanDerWaalsContact O-N 3.17Å; L419-D422 WeakPolarHBondContact CB-OD2 3.36Å; L419-D422 PolarHBondContact N-OD2 3.25Å; L419-D422 WeakPolarHBondContact O-CB 3.47Å; L419-D422 PolarHBondContact O-N 2.69Å; L419-A423 PolarHBondContact O-N 3.47Å; L419-V447 HydrophobicContact CB-CG1 4.39Å; L419-V447 HydrophobicContact CD2-CG1 4.02Å; L419-L450 HydrophobicContact CD1-CB 4.34Å; L419-L450 HydrophobicContact CD2-CB 3.83Å; L419-L450 HydrophobicContact CD2-CD1 3.98Å; L419-R451 HydrophobicContact CD1-CB 4.16Å; L419-R451 HydrophobicContact CD1-CG 3.75Å
420P80.9Confident80.4Confident78 Ų7831.9 Ų31.951%0.50617%0.166SC..Hα-helixtrans-52-40.6-178.6-29.936.7000113.9A423 C424 V447P420-A423 PolarHBondContact O-N 3.34Å; P420-C424 PolarHBondContact O-N 3.09Å; P420-C424 PolarHBondContact O-SG 3.01Å; P420-C424 VanDerWaalsContact O-SG 3.37Å; P420-V447 HydrophobicContact CG-CG1 4.15Å
421E84.4Confident79.5Confident4 Ų433.1 Ų33.12%0.01917%0.173CC..Hα-helixtrans-69.8-29.2176.963.4-89-150.800113.9I281 K348 K351 V352 L419 C424 V425 R451I281-E421 HydrophobicContact CD1-CB 4.15Å; K348-E421 HydrophobicContact CB-CB 3.94Å; K348-E421 VanDerWaalsContact CB-CD 3.48Å; K348-E421 HydrophobicContact CB-CG 3.8Å; K351-E421 HydrophobicContact CD-CG 4.37Å; V352-E421 HydrophobicContact CG2-CB 3.86Å; V352-E421 HydrophobicContact CG2-CG 3.95Å; L419-E421 PolarHBondContact O-N 3.27Å; L419-E421 VanDerWaalsContact O-N 3.17Å; E421-C424 WeakPolarHBondContact O-CB 3.24Å; E421-C424 PolarHBondContact O-N 2.9Å; E421-V425 WeakPolarHBondContact O-CG2 3.44Å; E421-V425 PolarHBondContact O-N 2.99Å; E421-R451 VanDerWaalsContact CD-NE 3.3Å; E421-R451 VanDerWaalsContact OE1-CD 3.25Å; E421-R451 WeakPolarHBondContact OE1-CD 2.96Å; E421-R451 WeakPolarHBondContact OE1-CG 3.18Å; E421-R451 IonicContact OE1-CZ 3.97Å; E421-R451 IonicContact OE1-NE 2.8Å; E421-R451 PolarHBondContact OE1-NE 3.35Å; E421-R451 IonicContact OE1-NH2 2.81Å; E421-R451 IonicContact OE2-CZ 3.46Å; E421-R451 IonicContact OE2-NE 3.44Å; E421-R451 PolarHBondContact OE2-NE 3.42Å; E421-R451 VanDerWaalsContact OE2-NE 3.15Å; E421-R451 IonicContact OE2-NH2 3.04Å; E421-R451 PolarHBondContact OE2-NH2 2.9Å
422D84.1Confident78.5Confident2 Ų242.7 Ų42.71%0.01120%0.203CC..Hα-helixtrans-69.5-40.2177.2-63.5-45.9000110.6K351 N355 Q415 L419 C424 V425 F426 L433K351-D422 WeakPolarHBondContact CE-OD1 3.27Å; K351-D422 VanDerWaalsContact NZ-CG 3.31Å; K351-D422 IonicContact NZ-OD1 3.09Å; K351-D422 PolarHBondContact NZ-OD1 2.77Å; K351-D422 IonicContact NZ-OD2 3.83Å; K351-D422 PolarHBondContact NZ-OD2 3.42Å; N355-D422 PolarHBondContact ND2-OD1 3.1Å; Q415-D422 PolarHBondContact NE2-OD2 3.02Å; L419-D422 WeakPolarHBondContact CB-OD2 3.36Å; L419-D422 PolarHBondContact N-OD2 3.25Å; L419-D422 WeakPolarHBondContact O-CB 3.47Å; L419-D422 PolarHBondContact O-N 2.69Å; D422-C424 PolarHBondContact O-N 2.79Å; D422-V425 CarbonylContact O-C 3.58Å; D422-V425 PolarHBondContact O-N 3.19Å; D422-V425 VanDerWaalsContact O-N 3.12Å; D422-F426 WeakPolarHBondContact O-CA 3.4Å; D422-F426 WeakPolarHBondContact O-CB 3.48Å; D422-F426 PolarHBondContact O-N 2.84Å; D422-L433 HydrophobicContact CB-CD1 3.97Å
423A72.9Confident77.3Confident10 Ų1037.3 Ų37.38%0.08318%0.179CC..Hα-helixtrans-60.2-35.3175.900000110.8L85 W87 L419 P420 V425L85-A423 HydrophobicContact CB-CB 4.28Å; L85-A423 HydrophobicContact CD1-CB 3.63Å; L85-A423 VanDerWaalsContact CD1-O 3.27Å; L85-A423 WeakPolarHBondContact CD1-O 3.31Å; L85-A423 HydrophobicContact CG-CB 4.31Å; W87-A423 PolarHBondContact NE1-O 2.74Å; L419-A423 PolarHBondContact O-N 3.47Å; P420-A423 PolarHBondContact O-N 3.34Å; A423-V425 VanDerWaalsContact C-N 3.35Å; A423-V425 PolarHBondContact O-N 2.9Å
424C73.1Confident75.6Confident49 Ų4942.9 Ų42.933%0.33121%0.205SC..Hα-helixtrans-69.3-24.9177.1-660000114.4R172 P420 E421 D422R172-C424 PolarHBondContact NH1-O 3.47Å; R172-C424 PolarHBondContact NH2-O 2.99Å; P420-C424 PolarHBondContact O-N 3.09Å; P420-C424 PolarHBondContact O-SG 3.01Å; P420-C424 VanDerWaalsContact O-SG 3.37Å; E421-C424 WeakPolarHBondContact O-CB 3.24Å; E421-C424 PolarHBondContact O-N 2.9Å; D422-C424 PolarHBondContact O-N 2.79Å
425V77.9Confident74Confident1 Ų141.7 Ų41.71%0.00620%0.199CC..Hα-helixtrans-12311.9-174.4-56.30000113.4I281 S285 V352 E421 D422 A423 D427 I428 L429I281-V425 HydrophobicContact CG2-CG1 4.04Å; S285-V425 WeakPolarHBondContact OG-CG1 3.28Å; V352-V425 HydrophobicContact CG1-CG1 3.98Å; V352-V425 HydrophobicContact CG1-CG2 4.21Å; V352-V425 HydrophobicContact CG2-CG1 4.4Å; V352-V425 HydrophobicContact CG2-CG2 4.18Å; E421-V425 WeakPolarHBondContact O-CG2 3.44Å; E421-V425 PolarHBondContact O-N 2.99Å; D422-V425 CarbonylContact O-C 3.58Å; D422-V425 PolarHBondContact O-N 3.19Å; D422-V425 VanDerWaalsContact O-N 3.12Å; A423-V425 VanDerWaalsContact C-N 3.35Å; A423-V425 PolarHBondContact O-N 2.9Å; V425-D427 PolarHBondContact O-N 2.8Å; V425-I428 HydrophobicContact CB-CD1 4.43Å; V425-I428 WeakPolarHBondContact O-CB 3.44Å; V425-I428 PolarHBondContact O-N 3.45Å; V425-I428 VanDerWaalsContact O-N 3.16Å; V425-L429 HydrophobicContact CB-CD1 4.23Å; V425-L429 HydrophobicContact CB-CG 4.34Å; V425-L429 HydrophobicContact CG2-CD1 3.48Å; V425-L429 VanDerWaalsContact CG2-CD1 3.48Å; V425-L429 HydrophobicContact CG2-CG 4.03Å; V425-L429 PolarHBondContact O-N 3.15Å
426F75.3Confident72.6Confident24 Ų2447.8 Ų47.811%0.10522%0.221CC..Hα-helixtrans-61.5-43.8-170.4177.9-87.5000113.3W87 D422 I428 K430 L431 L433W87-F426 HydrophobicContact CB-CD1 3.14Å; W87-F426 HydrophobicContact CB-CE1 3.08Å; W87-F426 HydrophobicContact CB-CE2 4.45Å; W87-F426 HydrophobicContact CB-CG 3.91Å; W87-F426 HydrophobicContact CB-CZ 3.78Å; W87-F426 AromaticContact CD1-CD1 3.48Å; W87-F426 VanDerWaalsContact CD1-CD1 3.48Å; W87-F426 AromaticContact CD1-CG 3.4Å; W87-F426 VanDerWaalsContact CD1-CG 3.4Å; W87-F426 HydrophobicContact CD2-CB 4.48Å; W87-F426 AromaticContact CD2-CD1 3.89Å; W87-F426 HydrophobicContact CD2-CD1 3.89Å; W87-F426 HydrophobicContact CD2-CG 4.45Å; W87-F426 HydrophobicContact CE3-CD1 4.44Å; W87-F426 HydrophobicContact CG-CB 4.12Å; W87-F426 AromaticContact CG-CD1 3.25Å; W87-F426 HydrophobicContact CG-CD1 3.25Å; W87-F426 AromaticContact CG-CE1 3.79Å; W87-F426 HydrophobicContact CG-CE1 3.79Å; W87-F426 AromaticContact CG-CG 3.72Å; W87-F426 HydrophobicContact CG-CG 3.72Å; W87-F426 AromaticContact NE1-CG 3.96Å; D422-F426 WeakPolarHBondContact O-CA 3.4Å; D422-F426 WeakPolarHBondContact O-CB 3.48Å; D422-F426 PolarHBondContact O-N 2.84Å; F426-I428 PolarHBondContact O-N 2.9Å; F426-K430 WeakPolarHBondContact O-CA 3.39Å; F426-K430 PolarHBondContact O-N 3.35Å; F426-L431 WeakPolarHBondContact CE2-O 3.21Å; F426-L433 HydrophobicContact CD2-CD1 4.2Å; F426-L433 HydrophobicContact CE2-CD1 4.49Å
427D70.7Confident71.1Confident32 Ų3249.4 Ų49.417%0.17123%0.234CC..Hα-helixtrans-65-27.3178.255-30.7000112.9R172 V425 K430R172-D427 IonicContact CZ-OD1 2.65Å; R172-D427 IonicContact CZ-OD2 3.03Å; R172-D427 VanDerWaalsContact NE-CG 3.34Å; R172-D427 IonicContact NE-OD1 3.94Å; R172-D427 PolarHBondContact NE-OD1 3.01Å; R172-D427 VanDerWaalsContact NE-OD1 3.13Å; R172-D427 IonicContact NE-OD2 3.71Å; R172-D427 PolarHBondContact NE-OD2 3.32Å; R172-D427 IonicContact NH2-OD1 3.98Å; R172-D427 PolarHBondContact NH2-OD1 2.91Å; R172-D427 IonicContact NH2-OD2 3.32Å; R172-D427 PolarHBondContact NH2-OD2 3.35Å; R172-D427 VanDerWaalsContact NH2-OD2 3.16Å; V425-D427 PolarHBondContact O-N 2.8Å; D427-K430 WeakPolarHBondContact O-CE 3.44Å; D427-K430 WeakPolarHBondContact O-CG 3.16Å
428I76.4Confident70.1Confident3 Ų350.1 Ų50.12%0.01524%0.237CC..Hα-helixtrans-76.9-60.2175-43.3-176.2000109.3S285 M288 E289 V425 F426 K430S285-I428 VanDerWaalsContact CB-CD1 3.44Å; M288-I428 HydrophobicContact CB-CG2 3.73Å; M288-I428 HydrophobicContact SD-CG2 4.48Å; E289-I428 HydrophobicContact CG-CD1 3.93Å; E289-I428 HydrophobicContact CG-CG1 3.97Å; E289-I428 HydrophobicContact CG-CG2 4.15Å; E289-I428 WeakPolarHBondContact OE1-CG1 3.19Å; V425-I428 HydrophobicContact CB-CD1 4.43Å; V425-I428 WeakPolarHBondContact O-CB 3.44Å; V425-I428 PolarHBondContact O-N 3.45Å; V425-I428 VanDerWaalsContact O-N 3.16Å; F426-I428 PolarHBondContact O-N 2.9Å; I428-K430 PolarHBondContact O-N 3Å
429L79.3Confident68.7Low7 Ų754.7 Ų54.74%0.03727%0.265CS..Hα-helixtrans-81-18.7-170.8-55.1-178.3000113.3M288 N355 W356 L359 V425 L431M288-L429 HydrophobicContact SD-CD2 3.96Å; N355-L429 HydrophobicContact CB-CD1 3.46Å; N355-L429 VanDerWaalsContact CB-CD1 3.46Å; W356-L429 HydrophobicContact CB-CD2 3.73Å; W356-L429 HydrophobicContact CG-CD2 4.1Å; L359-L429 HydrophobicContact CD1-CB 4.04Å; L359-L429 HydrophobicContact CD1-CD2 4.4Å; L359-L429 WeakPolarHBondContact CD1-O 3.13Å; V425-L429 HydrophobicContact CB-CD1 4.23Å; V425-L429 HydrophobicContact CB-CG 4.34Å; V425-L429 HydrophobicContact CG2-CD1 3.48Å; V425-L429 VanDerWaalsContact CG2-CD1 3.48Å; V425-L429 HydrophobicContact CG2-CG 4.03Å; V425-L429 PolarHBondContact O-N 3.15Å; L429-L431 HydrophobicContact CB-CD1 4.09Å; L429-L431 HydrophobicContact CB-CG 3.88Å; L429-L431 HydrophobicContact CD1-CD1 4.33Å; L429-L431 PolarHBondContact O-N 3.25Å
430K72.1Confident67.7Low137 Ų13761.8 Ų61.860%0.59629%0.292SS*.  trans44.533.9179.6-61.5173.6-172.6152.60113.5F426 D427 I428 R432F426-K430 WeakPolarHBondContact O-CA 3.39Å; F426-K430 PolarHBondContact O-N 3.35Å; D427-K430 WeakPolarHBondContact O-CE 3.44Å; D427-K430 WeakPolarHBondContact O-CG 3.16Å; I428-K430 PolarHBondContact O-N 3Å; K430-R432 PolarHBondContact O-N 3.18Å
431L70.3Confident67.1Low26 Ų2669.5 Ų69.514%0.13631%0.311CS..  trans-62.6135.6-177-68.3165.9000109.6N355 L359 F426 L429 L433N355-L431 HydrophobicContact CB-CD1 3.82Å; N355-L431 WeakPolarHBondContact OD1-CD1 3.24Å; L359-L431 HydrophobicContact CD1-CD2 3.86Å; L359-L431 HydrophobicContact CD1-CG 4.45Å; L359-L431 HydrophobicContact CD2-CD2 4.12Å; L359-L431 HydrophobicContact CG-CD2 4.17Å; F426-L431 WeakPolarHBondContact CE2-O 3.21Å; L429-L431 HydrophobicContact CB-CD1 4.09Å; L429-L431 HydrophobicContact CB-CG 3.88Å; L429-L431 HydrophobicContact CD1-CD1 4.33Å; L429-L431 PolarHBondContact O-N 3.25Å; L431-L433 HydrophobicContact CB-CG 4.13Å; L431-L433 PolarHBondContact O-N 3.21Å
432R64.7Low66.9Low235 Ų23570.9 Ų70.989%0.88732%0.318SS*.  trans-72.870172.2-67.6-173.7-178.7173.61.2110.7K430 H434K430-R432 PolarHBondContact O-N 3.18Å; R432-H434 PolarHBondContact O-N 3.14Å
433L61.7Low67Low14 Ų1471.9 Ų71.97%0.07333%0.325CS..  trans-71.5123.9170.8-62.4170.5000107.7Q415 S418 D422 F426 L431 Q435Q415-L433 HydrophobicContact CB-CD2 4.23Å; Q415-L433 HydrophobicContact CG-CD2 4.03Å; S418-L433 VanDerWaalsContact OG-CD1 3.32Å; S418-L433 WeakPolarHBondContact OG-CD1 3.33Å; D422-L433 HydrophobicContact CB-CD1 3.97Å; F426-L433 HydrophobicContact CD2-CD1 4.2Å; F426-L433 HydrophobicContact CE2-CD1 4.49Å; L431-L433 HydrophobicContact CB-CG 4.13Å; L431-L433 PolarHBondContact O-N 3.21Å; L433-Q435 PolarHBondContact O-N 3.3Å; L433-Q435 VanDerWaalsContact O-N 3.12Å
434H54.3Low67.5Low121 Ų12178.3 Ų78.356%0.5635%0.353SS*.  trans-67.7112.8174.4-74.236.7000106.7E416 R432 R436E416-H434 CarbonylContact C-O 3.58Å; E416-H434 HydrophobicContact CB-CB 4.47Å; E416-H434 HydrophobicContact CG-CB 4.46Å; R432-H434 PolarHBondContact O-N 3.14Å; H434-R436 VanDerWaalsContact C-N 3.32Å; H434-R436 PolarHBondContact O-N 3.49Å
435Q52.1Low68.2Low62 Ų6277.4 Ų77.429%0.2935%0.346SS..  trans-85.670.3-169.3-70.4178.3-6.900111.6N88 L433 V437N88-Q435 VanDerWaalsContact CB-OE1 3.3Å; N88-Q435 PolarHBondContact ND2-NE2 3.09Å; N88-Q435 PolarHBondContact ND2-OE1 3.28Å; N88-Q435 PolarHBondContact OD1-NE2 3.05Å; L433-Q435 PolarHBondContact O-N 3.3Å; L433-Q435 VanDerWaalsContact O-N 3.12Å; Q435-V437 PolarHBondContact O-N 3.43Å; Q435-V437 VanDerWaalsContact O-N 3.11Å
436R55.2Low68.8Low142 Ų14277.4 Ų77.454%0.53635%0.346SS..  trans-67114.2161.4-89.9-176.1166.7162.2-6107.8E416 H434 I438E416-R436 WeakPolarHBondContact OE2-CD 3.31Å; E416-R436 IonicContact OE2-CZ 2.81Å; E416-R436 IonicContact OE2-NE 2.73Å; E416-R436 IonicContact OE2-NH1 3.17Å; E416-R436 PolarHBondContact OE2-NH1 3.23Å; H434-R436 VanDerWaalsContact C-N 3.32Å; H434-R436 PolarHBondContact O-N 3.49Å; R436-I438 PolarHBondContact O-N 3.23Å
437V49.6Very low69.4Low74 Ų7477 Ų7745%0.44835%0.346SS..  trans-60.5101171.3179.50000107.3Q435 T439Q435-V437 PolarHBondContact O-N 3.43Å; Q435-V437 VanDerWaalsContact O-N 3.11Å; V437-T439 HydrophobicContact CG1-CG2 4.36Å; V437-T439 PolarHBondContact O-N 3.25Å; V437-T439 VanDerWaalsContact O-N 3.14Å
438I56.5Low70.3Confident24 Ų2475.5 Ų75.512%0.12334%0.338CS..  trans-72.5110.5169.6-57-168.6000106.7T83 L405 V417 R436 R440 M442T83-I438 VanDerWaalsContact CB-O 3.31Å; T83-I438 WeakPolarHBondContact CB-O 3.31Å; T83-I438 WeakPolarHBondContact CG2-O 3.44Å; T83-I438 PolarHBondContact OG1-O 2.86Å; L405-I438 HydrophobicContact CD1-CD1 3.99Å; V417-I438 HydrophobicContact CB-CD1 3.96Å; V417-I438 HydrophobicContact CB-CG1 4.42Å; V417-I438 HydrophobicContact CG1-CD1 3.21Å; V417-I438 HydrophobicContact CG1-CG1 3.83Å; V417-I438 HydrophobicContact CG2-CD1 3.5Å; V417-I438 HydrophobicContact CG2-CG1 3.69Å; R436-I438 PolarHBondContact O-N 3.23Å; I438-R440 HydrophobicContact CG2-CB 4.15Å; I438-R440 WeakPolarHBondContact CG2-O 3.18Å; I438-R440 PolarHBondContact O-N 3.18Å; I438-M442 HydrophobicContact CD1-CG 4.05Å; I438-M442 HydrophobicContact CD1-SD 3.39Å; I438-M442 WeakPolarHBondContact CD1-SD 3.1Å
439T48.2Very low71.1Confident102 Ų10275.4 Ų75.463%0.62634%0.337SS*.  trans-77.3-14172.654.70000112.9V437V437-T439 HydrophobicContact CG1-CG2 4.36Å; V437-T439 PolarHBondContact O-N 3.25Å; V437-T439 VanDerWaalsContact O-N 3.14Å
440R62.6Low71.7Confident151 Ų15175.2 Ų75.257%0.5734%0.336SS*.SBendtrans-100.7136.5-177.2-62.1-178.4-179.71733112.5I438 M442I438-R440 HydrophobicContact CG2-CB 4.15Å; I438-R440 WeakPolarHBondContact CG2-O 3.18Å; I438-R440 PolarHBondContact O-N 3.18Å; R440-M442 PolarHBondContact O-N 3.29Å
441R68.4Low72.7Confident239 Ų23970.4 Ų70.490%0.90231%0.314SS*.PPolyproline II helixtrans-65.7121.4168.6-167.7175.7-178.5-174.4-1109.4
442M79.5Confident73.8Confident33 Ų3369.1 Ų69.116%0.16331%0.308CS..PPolyproline II helixtrans-81.2144.8170.7-66-173.765.200110.5I402 L405 I438 R440 A446 V447 L450I402-M442 HydrophobicContact CG2-CE 3.93Å; L405-M442 HydrophobicContact CD1-SD 4.45Å; I438-M442 HydrophobicContact CD1-CG 4.05Å; I438-M442 HydrophobicContact CD1-SD 3.39Å; I438-M442 WeakPolarHBondContact CD1-SD 3.1Å; R440-M442 PolarHBondContact O-N 3.29Å; M442-A446 HydrophobicContact CB-CB 4.5Å; M442-A446 HydrophobicContact CE-CB 3.61Å; M442-V447 HydrophobicContact CB-CG2 3.97Å; M442-L450 HydrophobicContact CE-CD1 3.61Å; M442-L450 HydrophobicContact CE-CG 4.3Å; M442-L450 HydrophobicContact SD-CD1 4.24Å
443S86Confident75.2Confident24 Ų2458 Ų5817%0.16827%0.265CS..PPolyproline II helixtrans-74.1154.2170.464.90000111.3E401 T445 A446 V447E401-S443 WeakPolarHBondContact OE2-CB 3.42Å; E401-S443 PolarHBondContact OE2-N 3.06Å; E401-S443 PolarHBondContact OE2-OG 3.42Å; S443-T445 PolarHBondContact O-N 2.94Å; S443-A446 WeakPolarHBondContact O-CB 3.22Å; S443-A446 PolarHBondContact O-N 3.34Å; S443-A446 PolarHBondContact OG-N 3.37Å; S443-V447 WeakPolarHBondContact O-CG2 3.43Å; S443-V447 PolarHBondContact O-N 3.47Å
444E84.4Confident76.7Confident145 Ų14557.3 Ų57.368%0.67826%0.262SS*.Hα-helixtrans-56.1-34.8176.1-65.5-177.2166.600112.4V447 C448E444-V447 PolarHBondContact O-N 3.22Å; E444-C448 VanDerWaalsContact O-CB 3.29Å; E444-C448 WeakPolarHBondContact O-CB 3.11Å; E444-C448 PolarHBondContact O-N 3.36Å
445T87.5Confident78.5Confident30 Ų3051.6 Ų51.618%0.18424%0.236CC..Hα-helixtrans-63.4-40.7174.6-44.30000112.1L338 Q342 I398 S443 C448 F449L338-T445 HydrophobicContact CD2-CG2 3.58Å; L338-T445 HydrophobicContact CG-CG2 3.8Å; Q342-T445 PolarHBondContact OE1-OG1 3Å; I398-T445 HydrophobicContact CD1-CG2 3.82Å; S443-T445 PolarHBondContact O-N 2.94Å; T445-C448 PolarHBondContact O-N 2.94Å; T445-F449 PolarHBondContact O-N 2.91Å
446A89.3Confident80.3Confident0 Ų049.1 Ų49.10%022%0.224CC..Hα-helixtrans-71-37.6176.300000112.1E401 I402 M442 S443 F449 L450E401-A446 HydrophobicContact CB-CB 4.14Å; E401-A446 VanDerWaalsContact OE2-CB 3.24Å; E401-A446 WeakPolarHBondContact OE2-CB 3.34Å; I402-A446 HydrophobicContact CG2-CB 4Å; M442-A446 HydrophobicContact CB-CB 4.5Å; M442-A446 HydrophobicContact CE-CB 3.61Å; S443-A446 WeakPolarHBondContact O-CB 3.22Å; S443-A446 PolarHBondContact O-N 3.34Å; S443-A446 PolarHBondContact OG-N 3.37Å; A446-F449 WeakPolarHBondContact O-CB 3.4Å; A446-F449 PolarHBondContact O-N 2.82Å; A446-L450 PolarHBondContact O-N 3.48Å; A446-L450 VanDerWaalsContact O-N 3.11Å
447V88.7Confident82.1Confident16 Ų1643 Ų4310%0.09720%0.201CC..Hα-helixtrans-63.7-42.9172.7-177.40000110.5L419 P420 M442 S443 E444 F449 L450 R451L419-V447 HydrophobicContact CB-CG1 4.39Å; L419-V447 HydrophobicContact CD2-CG1 4.02Å; P420-V447 HydrophobicContact CG-CG1 4.15Å; M442-V447 HydrophobicContact CB-CG2 3.97Å; S443-V447 WeakPolarHBondContact O-CG2 3.43Å; S443-V447 PolarHBondContact O-N 3.47Å; E444-V447 PolarHBondContact O-N 3.22Å; V447-F449 VanDerWaalsContact C-N 3.33Å; V447-F449 PolarHBondContact O-N 3.47Å; V447-L450 PolarHBondContact O-N 3.48Å; V447-R451 WeakPolarHBondContact O-CB 3.47Å; V447-R451 PolarHBondContact O-N 3.31Å
448C90.8Very high84Confident1 Ų139.8 Ų39.81%0.00718%0.181CC..Hα-helixtrans-60-41.4173.6-174.90000112L338 Q342 E444 T445 L450 R451 I452L338-C448 HydrophobicContact CD1-CB 4.32Å; Q342-C448 HydrophobicContact CB-CB 4.01Å; E444-C448 VanDerWaalsContact O-CB 3.29Å; E444-C448 WeakPolarHBondContact O-CB 3.11Å; E444-C448 PolarHBondContact O-N 3.36Å; T445-C448 PolarHBondContact O-N 2.94Å; C448-L450 PolarHBondContact O-N 3.16Å; C448-R451 VanDerWaalsContact O-CB 3.27Å; C448-R451 WeakPolarHBondContact O-CB 3.32Å; C448-R451 PolarHBondContact O-N 3.49Å; C448-I452 WeakPolarHBondContact O-CG1 3.37Å; C448-I452 PolarHBondContact O-N 3.01Å
449F93Very high85.5Confident0 Ų038.7 Ų38.70%018%0.175CC..Hα-helixtrans-57.5-50175.7-176.8-78000111.8L338 L388 I391 N392 I398 I402 F406 T445 A446 V447 R451 I452 C453L338-F449 HydrophobicContact CD1-CB 4.31Å; L338-F449 HydrophobicContact CD2-CB 4.31Å; L338-F449 HydrophobicContact CD2-CD2 4.13Å; L388-F449 HydrophobicContact CB-CE2 3.97Å; L388-F449 HydrophobicContact CB-CZ 3.83Å; L388-F449 HydrophobicContact CD2-CD2 3.74Å; L388-F449 HydrophobicContact CD2-CE1 4.49Å; L388-F449 HydrophobicContact CD2-CE2 3.49Å; L388-F449 VanDerWaalsContact CD2-CE2 3.49Å; L388-F449 HydrophobicContact CD2-CG 4.37Å; L388-F449 HydrophobicContact CD2-CZ 3.9Å; L388-F449 HydrophobicContact CG-CE2 4.33Å; L388-F449 HydrophobicContact CG-CZ 4.41Å; L388-F449 WeakPolarHBondContact O-CE2 3.29Å; I391-F449 HydrophobicContact CB-CE2 4.12Å; I391-F449 HydrophobicContact CD1-CE2 4.44Å; I391-F449 HydrophobicContact CG2-CD2 4.22Å; I391-F449 HydrophobicContact CG2-CE2 4.03Å; N392-F449 HydrophobicContact CB-CZ 4.41Å; I398-F449 HydrophobicContact CG2-CD2 4.34Å; I402-F449 HydrophobicContact CD1-CD1 3.62Å; I402-F449 HydrophobicContact CD1-CE1 3.33Å; I402-F449 HydrophobicContact CD1-CE2 4.34Å; I402-F449 HydrophobicContact CD1-CG 4.27Å; I402-F449 HydrophobicContact CD1-CZ 3.73Å; F406-F449 HydrophobicContact CB-CE1 4.23Å; F406-F449 HydrophobicContact CD1-CE1 4.5Å; F406-F449 HydrophobicContact CD1-CZ 4.41Å; F406-F449 AromaticContact CD2-CE1 3.65Å; F406-F449 HydrophobicContact CD2-CE1 3.65Å; F406-F449 HydrophobicContact CD2-CZ 4.06Å; F406-F449 HydrophobicContact CE1-CZ 4.46Å; F406-F449 HydrophobicContact CE2-CE1 4.09Å; F406-F449 HydrophobicContact CE2-CZ 4.09Å; F406-F449 AromaticContact CG-CE1 3.87Å; F406-F449 HydrophobicContact CG-CE1 3.87Å; F406-F449 HydrophobicContact CG-CZ 4.2Å; F406-F449 HydrophobicContact CZ-CZ 4.3Å; T445-F449 PolarHBondContact O-N 2.91Å; A446-F449 WeakPolarHBondContact O-CB 3.4Å; A446-F449 PolarHBondContact O-N 2.82Å; V447-F449 VanDerWaalsContact C-N 3.33Å; V447-F449 PolarHBondContact O-N 3.47Å; F449-R451 VanDerWaalsContact C-N 3.34Å; F449-R451 PolarHBondContact O-N 3.12Å; F449-I452 PolarHBondContact O-N 2.93Å; F449-C453 VanDerWaalsContact CE1-SG 3.6Å; F449-C453 PolarHBondContact O-N 2.9Å; F449-C453 VanDerWaalsContact O-N 3.09Å; F449-C453 PolarHBondContact O-SG 3.49Å
450L92.1Very high87.4Confident3 Ų335 Ų352%0.01615%0.151CC..Hα-helixtrans-65.7-35.9177.8-67.3-177.3000112.3I402 L405 W413 L419 M442 A446 V447 C448 I452 C453 C454I402-L450 HydrophobicContact CG2-CG 4.5Å; L405-L450 HydrophobicContact CB-CD2 4.41Å; L405-L450 HydrophobicContact CD1-CD1 4.37Å; W413-L450 HydrophobicContact CZ2-CD2 4.09Å; L419-L450 HydrophobicContact CD1-CB 4.34Å; L419-L450 HydrophobicContact CD2-CB 3.83Å; L419-L450 HydrophobicContact CD2-CD1 3.98Å; M442-L450 HydrophobicContact CE-CD1 3.61Å; M442-L450 HydrophobicContact CE-CG 4.3Å; M442-L450 HydrophobicContact SD-CD1 4.24Å; A446-L450 PolarHBondContact O-N 3.48Å; A446-L450 VanDerWaalsContact O-N 3.11Å; V447-L450 PolarHBondContact O-N 3.48Å; C448-L450 PolarHBondContact O-N 3.16Å; L450-I452 VanDerWaalsContact C-N 3.33Å; L450-I452 PolarHBondContact O-N 3.45Å; L450-C453 WeakPolarHBondContact O-CB 3.39Å; L450-C453 PolarHBondContact O-N 3.47Å; L450-C453 VanDerWaalsContact O-N 3.13Å; L450-C454 PolarHBondContact O-N 3.48Å; L450-C454 PolarHBondContact O-SG 3.2Å
451R92.8Very high88.6Confident36 Ų3628.8 Ų28.814%0.13613%0.129CC..Hα-helixtrans-55.7-46172.1-118.5171.3-120.9132.2-7.4112.1K351 L419 E421 V447 C448 F449 C453 C454 L455K351-R451 HydrophobicContact CG-CG 4.41Å; L419-R451 HydrophobicContact CD1-CB 4.16Å; L419-R451 HydrophobicContact CD1-CG 3.75Å; E421-R451 VanDerWaalsContact CD-NE 3.3Å; E421-R451 VanDerWaalsContact OE1-CD 3.25Å; E421-R451 WeakPolarHBondContact OE1-CD 2.96Å; E421-R451 WeakPolarHBondContact OE1-CG 3.18Å; E421-R451 IonicContact OE1-CZ 3.97Å; E421-R451 IonicContact OE1-NE 2.8Å; E421-R451 PolarHBondContact OE1-NE 3.35Å; E421-R451 IonicContact OE1-NH2 2.81Å; E421-R451 IonicContact OE2-CZ 3.46Å; E421-R451 IonicContact OE2-NE 3.44Å; E421-R451 PolarHBondContact OE2-NE 3.42Å; E421-R451 VanDerWaalsContact OE2-NE 3.15Å; E421-R451 IonicContact OE2-NH2 3.04Å; E421-R451 PolarHBondContact OE2-NH2 2.9Å; V447-R451 WeakPolarHBondContact O-CB 3.47Å; V447-R451 PolarHBondContact O-N 3.31Å; C448-R451 VanDerWaalsContact O-CB 3.27Å; C448-R451 WeakPolarHBondContact O-CB 3.32Å; C448-R451 PolarHBondContact O-N 3.49Å; F449-R451 VanDerWaalsContact C-N 3.34Å; F449-R451 PolarHBondContact O-N 3.12Å; R451-C453 VanDerWaalsContact C-N 3.33Å; R451-C454 WeakPolarHBondContact O-CB 3.18Å; R451-C454 PolarHBondContact O-N 3.36Å; R451-L455 WeakPolarHBondContact O-CG 2.96Å; R451-L455 PolarHBondContact O-N 3.01Å
452I92.8Very high89.5Confident0 Ų017.6 Ų17.60%09%0.086CC..Hα-helixtrans-65-39.1177.2-66.5161.7000110.5L338 L341 L382 P383 L388 C448 F449 L450 C454 L455 R456L338-I452 HydrophobicContact CD1-CD1 3.47Å; L338-I452 VanDerWaalsContact CD1-CD1 3.47Å; L341-I452 HydrophobicContact CD1-CD1 3.65Å; L382-I452 HydrophobicContact CB-CG2 4.2Å; L382-I452 HydrophobicContact CD1-CG2 4.47Å; P383-I452 HydrophobicContact CG-CD1 4.13Å; L388-I452 HydrophobicContact CD1-CG2 4.09Å; L388-I452 HydrophobicContact CD2-CG2 4.16Å; C448-I452 WeakPolarHBondContact O-CG1 3.37Å; C448-I452 PolarHBondContact O-N 3.01Å; F449-I452 PolarHBondContact O-N 2.93Å; L450-I452 VanDerWaalsContact C-N 3.33Å; L450-I452 PolarHBondContact O-N 3.45Å; I452-C454 VanDerWaalsContact C-N 3.33Å; I452-C454 PolarHBondContact O-N 2.85Å; I452-L455 PolarHBondContact O-N 2.77Å; I452-R456 WeakPolarHBondContact O-CG 3.41Å; I452-R456 PolarHBondContact O-N 2.83Å
453C93.9Very high89.7Confident0 Ų017.7 Ų17.70%09%0.087CC..Hα-helixtrans-58.7-45.4174.7-610000111.1L410 W413 F449 L450 R451 R456 K457L410-C453 HydrophobicContact CD1-CB 4.39Å; L410-C453 HydrophobicContact CD2-CB 4.11Å; W413-C453 HydrophobicContact CD2-CB 4.43Å; W413-C453 HydrophobicContact CE3-CB 4.13Å; W413-C453 HydrophobicContact CH2-CB 3.97Å; W413-C453 HydrophobicContact CZ2-CB 4.28Å; W413-C453 HydrophobicContact CZ3-CB 3.89Å; F449-C453 VanDerWaalsContact CE1-SG 3.6Å; F449-C453 PolarHBondContact O-N 2.9Å; F449-C453 VanDerWaalsContact O-N 3.09Å; F449-C453 PolarHBondContact O-SG 3.49Å; L450-C453 WeakPolarHBondContact O-CB 3.39Å; L450-C453 PolarHBondContact O-N 3.47Å; L450-C453 VanDerWaalsContact O-N 3.13Å; R451-C453 VanDerWaalsContact C-N 3.33Å; C453-R456 PolarHBondContact O-N 2.6Å; C453-K457 WeakPolarHBondContact O-CB 3.23Å; C453-K457 PolarHBondContact O-N 3.08Å
454C92.4Very high89.5Confident1 Ų124.6 Ų24.61%0.00711%0.109CC..Hα-helixtrans-59.1-50.5175.4-57.90000111.5K351 Q415 L450 R451 I452 R456 K457 Y458K351-C454 HydrophobicContact CG-CB 4.17Å; Q415-C454 PolarHBondContact OE1-SG 2.84Å; L450-C454 PolarHBondContact O-N 3.48Å; L450-C454 PolarHBondContact O-SG 3.2Å; R451-C454 WeakPolarHBondContact O-CB 3.18Å; R451-C454 PolarHBondContact O-N 3.36Å; I452-C454 VanDerWaalsContact C-N 3.33Å; I452-C454 PolarHBondContact O-N 2.85Å; C454-R456 VanDerWaalsContact C-N 3.32Å; C454-R456 PolarHBondContact O-N 3.04Å; C454-K457 WeakPolarHBondContact O-CB 3.42Å; C454-K457 PolarHBondContact O-N 2.88Å; C454-K457 VanDerWaalsContact O-N 3.1Å; C454-Y458 HydrophobicContact CB-CE2 3.83Å; C454-Y458 WeakPolarHBondContact O-CD2 3.23Å; C454-Y458 WeakPolarHBondContact O-CE2 3.31Å; C454-Y458 PolarHBondContact O-N 3.46Å
455L92.3Very high89.4Confident0 Ų021 Ų210%09%0.092CC..Hα-helixtrans-60.6-38.4-179.2-68.7174.9000113L347 L350 K351 L382 R451 I452 Y458 A459L347-L455 HydrophobicContact CD2-CD1 3.92Å; L350-L455 HydrophobicContact CB-CD2 4.38Å; L350-L455 HydrophobicContact CD2-CD1 4.34Å; L350-L455 HydrophobicContact CD2-CD2 3.85Å; L350-L455 HydrophobicContact CG-CD2 3.81Å; K351-L455 HydrophobicContact CB-CD2 4.44Å; L382-L455 HydrophobicContact CD1-CB 3.89Å; L382-L455 HydrophobicContact CD1-CD1 3.86Å; R451-L455 WeakPolarHBondContact O-CG 2.96Å; R451-L455 PolarHBondContact O-N 3.01Å; I452-L455 PolarHBondContact O-N 2.77Å; L455-Y458 HydrophobicContact CD2-CD2 4.43Å; L455-A459 PolarHBondContact O-N 3.41Å
456R91.5Very high88.6Confident11 Ų1124 Ų244%0.04212%0.12CC..Hα-helixtrans-68.3-43.3172.6-69.2-161.780.783.45.6111.9V379 P383 L410 I452 C453 C454 Y458 A459 H460V379-R456 PolarHBondContact O-NH1 3.46Å; P383-R456 VanDerWaalsContact O-CD 3.31Å; P383-R456 WeakPolarHBondContact O-CD 3.34Å; P383-R456 PolarHBondContact O-NH1 2.64Å; L410-R456 HydrophobicContact CD1-CB 3.74Å; L410-R456 HydrophobicContact CD1-CG 4.39Å; I452-R456 WeakPolarHBondContact O-CG 3.41Å; I452-R456 PolarHBondContact O-N 2.83Å; C453-R456 PolarHBondContact O-N 2.6Å; C454-R456 VanDerWaalsContact C-N 3.32Å; C454-R456 PolarHBondContact O-N 3.04Å; R456-Y458 VanDerWaalsContact C-N 3.32Å; R456-Y458 PolarHBondContact O-N 2.89Å; R456-A459 WeakPolarHBondContact O-CB 3.46Å; R456-A459 PolarHBondContact O-N 3.48Å; R456-A459 VanDerWaalsContact O-N 3.09Å; R456-H460 PolarHBondContact O-CD2 3.11Å; R456-H460 PolarHBondContact O-N 2.99Å
457K91.4Very high87.8Confident13 Ų1327.8 Ų27.86%0.05714%0.136CC..Hα-helixtrans-54.9-48175.5-171.8-159-175.5-162.20110.8W413 E414 C453 C454 A459 H460 E461W413-K457 HydrophobicContact CE3-CB 4.48Å; W413-K457 HydrophobicContact CE3-CD 4.31Å; W413-K457 VanDerWaalsContact O-CD 3.23Å; W413-K457 WeakPolarHBondContact O-CD 3.35Å; W413-K457 WeakPolarHBondContact O-CE 3.3Å; E414-K457 IonicContact OE1-NZ 3.17Å; E414-K457 PolarHBondContact OE1-NZ 3.49Å; E414-K457 IonicContact OE2-NZ 2.96Å; E414-K457 PolarHBondContact OE2-NZ 3.4Å; C453-K457 WeakPolarHBondContact O-CB 3.23Å; C453-K457 PolarHBondContact O-N 3.08Å; C454-K457 WeakPolarHBondContact O-CB 3.42Å; C454-K457 PolarHBondContact O-N 2.88Å; C454-K457 VanDerWaalsContact O-N 3.1Å; K457-A459 VanDerWaalsContact C-N 3.29Å; K457-A459 PolarHBondContact O-N 3.19Å; K457-H460 CarbonylContact O-C 3.56Å; K457-H460 WeakPolarHBondContact O-CA 3.08Å; K457-H460 WeakPolarHBondContact O-CB 3.28Å; K457-H460 PolarHBondContact O-N 3.44Å; K457-E461 WeakPolarHBondContact CE-OE1 3.33Å; K457-E461 HydrophobicContact CG-CG 4.46Å; K457-E461 IonicContact NZ-OE1 2.73Å; K457-E461 PolarHBondContact NZ-OE1 3.21Å; K457-E461 VanDerWaalsContact NZ-OE1 3.09Å; K457-E461 PolarHBondContact O-N 3.43Å
458Y89.9Confident87Confident7 Ų727.3 Ų27.33%0.02713%0.134CC..Hα-helixtrans-59.7-38.7176.8-62-51.1000112.4K351 C354 N355 Q358 C454 L455 R456 H460 E461 F462K351-Y458 HydrophobicContact CG-CE2 4.44Å; K351-Y458 PolarHBondContact NZ-OH 3.41Å; C354-Y458 HydrophobicContact CB-CD1 4.25Å; C354-Y458 HydrophobicContact CB-CD2 3.27Å; C354-Y458 HydrophobicContact CB-CE2 3.67Å; C354-Y458 HydrophobicContact CB-CG 3.65Å; N355-Y458 PolarHBondContact OD1-OH 2.81Å; Q358-Y458 VanDerWaalsContact OE1-CE1 3.3Å; C454-Y458 HydrophobicContact CB-CE2 3.83Å; C454-Y458 WeakPolarHBondContact O-CD2 3.23Å; C454-Y458 WeakPolarHBondContact O-CE2 3.31Å; C454-Y458 PolarHBondContact O-N 3.46Å; L455-Y458 HydrophobicContact CD2-CD2 4.43Å; R456-Y458 VanDerWaalsContact C-N 3.32Å; R456-Y458 PolarHBondContact O-N 2.89Å; Y458-H460 VanDerWaalsContact C-N 3.28Å; Y458-H460 PolarHBondContact O-N 3.49Å; Y458-E461 WeakPolarHBondContact CD1-OE2 3.44Å; Y458-E461 PolarHBondContact O-N 2.74Å; Y458-F462 HydrophobicContact CG-CZ 4.46Å; Y458-F462 VanDerWaalsContact O-CB 3.3Å; Y458-F462 WeakPolarHBondContact O-CB 3.5Å; Y458-F462 WeakPolarHBondContact O-CD2 3.29Å; Y458-F462 WeakPolarHBondContact O-CG 3.48Å; Y458-F462 PolarHBondContact O-N 3.28Å
459A88.8Confident86.2Confident1 Ų127.6 Ų27.61%0.00814%0.137CC..Hα-helixtrans-61.2-38.7173.800000112F375 V379 L455 R456 K457 M463 F479F375-A459 HydrophobicContact CE1-CB 3.96Å; F375-A459 HydrophobicContact CZ-CB 4.32Å; V379-A459 HydrophobicContact CG1-CB 3.85Å; V379-A459 HydrophobicContact CG2-CB 4.24Å; L455-A459 PolarHBondContact O-N 3.41Å; R456-A459 WeakPolarHBondContact O-CB 3.46Å; R456-A459 PolarHBondContact O-N 3.48Å; R456-A459 VanDerWaalsContact O-N 3.09Å; K457-A459 VanDerWaalsContact C-N 3.29Å; K457-A459 PolarHBondContact O-N 3.19Å; A459-M463 WeakPolarHBondContact O-CB 3.42Å; A459-M463 VanDerWaalsContact O-CG 3.29Å; A459-M463 WeakPolarHBondContact O-CG 3.25Å; A459-M463 PolarHBondContact O-N 2.84Å; A459-M463 VanDerWaalsContact O-N 3.13Å; A459-F479 HydrophobicContact CB-CD1 4.12Å; A459-F479 HydrophobicContact CB-CE1 3.59Å; A459-F479 HydrophobicContact CB-CE2 4.12Å; A459-F479 HydrophobicContact CB-CZ 3.61Å
460H88.1Confident85.6Confident25 Ų2528.2 Ų28.212%0.11614%0.14CC..Hα-helixtrans-63.5-41.9171-73.4-75.5000113.7E385 R456 K457 Y458 M463 F479E385-H460 IonicContact OE1-CD2 3.71Å; E385-H460 IonicContact OE1-CE1 3.54Å; E385-H460 IonicContact OE1-NE2 3.01Å; E385-H460 PolarHBondContact OE1-NE2 3.3Å; R456-H460 PolarHBondContact O-CD2 3.11Å; R456-H460 PolarHBondContact O-N 2.99Å; K457-H460 CarbonylContact O-C 3.56Å; K457-H460 WeakPolarHBondContact O-CA 3.08Å; K457-H460 WeakPolarHBondContact O-CB 3.28Å; K457-H460 PolarHBondContact O-N 3.44Å; Y458-H460 VanDerWaalsContact C-N 3.28Å; Y458-H460 PolarHBondContact O-N 3.49Å; H460-M463 HydrophobicContact CB-CE 4.36Å; H460-M463 WeakPolarHBondContact ND1-CE 3.37Å; H460-F479 AromaticContact NE2-CZ 3.63Å
461E86.8Confident85.1Confident20 Ų2035.4 Ų35.49%0.09317%0.167CC..Hα-helixtrans-70-46.2178.8-69.1175.5153.400111.8Q358 K457 Y458 M463 R464 H465Q358-E461 VanDerWaalsContact CD-OE2 3.24Å; Q358-E461 PolarHBondContact NE2-OE1 3.44Å; Q358-E461 PolarHBondContact NE2-OE2 3.22Å; K457-E461 WeakPolarHBondContact CE-OE1 3.33Å; K457-E461 HydrophobicContact CG-CG 4.46Å; K457-E461 IonicContact NZ-OE1 2.73Å; K457-E461 PolarHBondContact NZ-OE1 3.21Å; K457-E461 VanDerWaalsContact NZ-OE1 3.09Å; K457-E461 PolarHBondContact O-N 3.43Å; Y458-E461 WeakPolarHBondContact CD1-OE2 3.44Å; Y458-E461 PolarHBondContact O-N 2.74Å; E461-M463 VanDerWaalsContact C-N 3.29Å; E461-M463 PolarHBondContact O-N 3.49Å; E461-R464 VanDerWaalsContact O-CB 3.27Å; E461-R464 WeakPolarHBondContact O-CB 3.36Å; E461-R464 PolarHBondContact O-N 3.4Å; E461-H465 PolarHBondContact O-CD2 3.47Å
462F87.2Confident84.6Confident3 Ų336.5 Ų36.51%0.01318%0.175CC..Hα-helixtrans-62.8-34.6178.7-62.4-18.8000112.3C354 L357 Q358 L364 W372 F375 Y458 R464 H465 T468 L470C354-F462 HydrophobicContact CB-CE2 4.36Å; C354-F462 HydrophobicContact CB-CZ 4.18Å; L357-F462 HydrophobicContact CB-CZ 4.18Å; Q358-F462 HydrophobicContact CB-CE1 4.37Å; L364-F462 HydrophobicContact CD1-CD1 3.77Å; L364-F462 HydrophobicContact CD1-CD2 4.36Å; L364-F462 HydrophobicContact CD1-CE1 3.67Å; L364-F462 HydrophobicContact CD1-CE2 4.27Å; L364-F462 HydrophobicContact CD1-CG 4.13Å; L364-F462 HydrophobicContact CD1-CZ 3.93Å; L364-F462 HydrophobicContact CD2-CD1 3.82Å; L364-F462 HydrophobicContact CD2-CE1 4.16Å; L364-F462 HydrophobicContact CG-CD1 4.49Å; W372-F462 HydrophobicContact CH2-CB 4.11Å; W372-F462 HydrophobicContact CH2-CD2 4.03Å; W372-F462 HydrophobicContact CH2-CG 4.13Å; W372-F462 HydrophobicContact CZ3-CB 4.07Å; W372-F462 AromaticContact CZ3-CD2 3.86Å; W372-F462 HydrophobicContact CZ3-CD2 3.86Å; W372-F462 HydrophobicContact CZ3-CG 4.24Å; F375-F462 AromaticContact CE1-CD2 3.92Å; F375-F462 HydrophobicContact CE1-CD2 3.92Å; F375-F462 HydrophobicContact CE1-CE2 4.45Å; F375-F462 AromaticContact CZ-CD2 3.98Å; F375-F462 HydrophobicContact CZ-CD2 3.98Å; F375-F462 HydrophobicContact CZ-CE2 4.08Å; Y458-F462 HydrophobicContact CG-CZ 4.46Å; Y458-F462 VanDerWaalsContact O-CB 3.3Å; Y458-F462 WeakPolarHBondContact O-CB 3.5Å; Y458-F462 WeakPolarHBondContact O-CD2 3.29Å; Y458-F462 WeakPolarHBondContact O-CG 3.48Å; Y458-F462 PolarHBondContact O-N 3.28Å; F462-R464 PolarHBondContact O-N 3.24Å; F462-H465 WeakPolarHBondContact O-CB 3.5Å; F462-H465 PolarHBondContact O-N 3Å; F462-T468 WeakPolarHBondContact O-CG2 3.2Å; F462-T468 PolarHBondContact O-OG1 3.24Å; F462-L470 HydrophobicContact CB-CD1 4.14Å
463M84Confident84Confident35 Ų3539 Ų3917%0.17219%0.188CC..Hα-helixtrans-60.6-26.5171-84.3-168.9-51.300114.4A459 H460 E461 H465 L470 I472 F479A459-M463 WeakPolarHBondContact O-CB 3.42Å; A459-M463 VanDerWaalsContact O-CG 3.29Å; A459-M463 WeakPolarHBondContact O-CG 3.25Å; A459-M463 PolarHBondContact O-N 2.84Å; A459-M463 VanDerWaalsContact O-N 3.13Å; H460-M463 HydrophobicContact CB-CE 4.36Å; H460-M463 WeakPolarHBondContact ND1-CE 3.37Å; E461-M463 VanDerWaalsContact C-N 3.29Å; E461-M463 PolarHBondContact O-N 3.49Å; M463-H465 PolarHBondContact O-N 3.13Å; M463-L470 HydrophobicContact CB-CB 4.4Å; M463-L470 HydrophobicContact CG-CB 3.49Å; M463-L470 VanDerWaalsContact CG-CB 3.49Å; M463-L470 HydrophobicContact CG-CD1 4.41Å; M463-I472 HydrophobicContact CE-CD1 3.55Å; M463-I472 HydrophobicContact CE-CG1 3.9Å; M463-I472 HydrophobicContact SD-CD1 4Å; M463-I472 HydrophobicContact SD-CG1 3.64Å; M463-F479 HydrophobicContact CE-CD1 3.91Å; M463-F479 HydrophobicContact CE-CE1 3.42Å; M463-F479 VanDerWaalsContact CE-CE1 3.42Å; M463-F479 HydrophobicContact CG-CD1 4.32Å; M463-F479 HydrophobicContact SD-CD1 3.56Å; M463-F479 VanDerWaalsContact SD-CD1 3.56Å; M463-F479 HydrophobicContact SD-CE1 3.76Å
464R83.1Confident83Confident169 Ų16945.5 Ų45.564%0.63822%0.223SC*.THydrogen-bonded Turntrans-67.8-19.2176.7-62.6178.1177.1156.11.9111.6S411 E461 F462S411-R464 PolarHBondContact O-NH2 2.65Å; S411-R464 VanDerWaalsContact O-NH2 3.12Å; E461-R464 VanDerWaalsContact O-CB 3.27Å; E461-R464 WeakPolarHBondContact O-CB 3.36Å; E461-R464 PolarHBondContact O-N 3.4Å; F462-R464 PolarHBondContact O-N 3.24Å
465H80.6Confident81.7Confident71 Ų7149.7 Ų49.733%0.32925%0.252SS..SBendtrans-90.3107.6176.5-63.4-75.2000110.6E461 F462 M463 F467 T468E461-H465 PolarHBondContact O-CD2 3.47Å; F462-H465 WeakPolarHBondContact O-CB 3.5Å; F462-H465 PolarHBondContact O-N 3Å; M463-H465 PolarHBondContact O-N 3.13Å; H465-F467 HydrophobicContact CB-CD1 4.01Å; H465-F467 HydrophobicContact CB-CE1 3.58Å; H465-F467 HydrophobicContact CB-CE2 4.26Å; H465-F467 HydrophobicContact CB-CZ 3.72Å; H465-F467 AromaticContact CG-CE1 3.94Å; H465-F467 AromaticContact ND1-CE1 3.89Å; H465-F467 PolarHBondContact O-N 2.99Å; H465-T468 HydrophobicContact CB-CG2 3.93Å; H465-T468 PolarHBondContact O-N 3.16Å; H465-T468 PolarHBondContact O-OG1 3.36Å
466A70.4Confident80.8Confident92 Ų9251.1 Ų51.176%0.7626%0.261SS*.G310 helixtrans-54.1-30.7-175.400000114.5T468 G469A466-T468 PolarHBondContact O-N 3.3Å; A466-G469 PolarHBondContact O-N 3.23Å
467F73.4Confident79.8Confident79 Ų7955 Ų5535%0.34628%0.282SS..G310 helixtrans-69.6-15.8-179.162.6-104.3000114.2L364 R365 H465 G469L364-F467 HydrophobicContact CB-CE2 4.32Å; L364-F467 HydrophobicContact CB-CZ 4.29Å; L364-F467 HydrophobicContact CD2-CE2 4.18Å; L364-F467 HydrophobicContact CD2-CZ 3.88Å; L364-F467 HydrophobicContact CG-CE2 3.96Å; L364-F467 HydrophobicContact CG-CZ 4.09Å; R365-F467 VanDerWaalsContact CA-CE2 3.48Å; R365-F467 HydrophobicContact CB-CD2 4.14Å; R365-F467 HydrophobicContact CB-CE2 3.91Å; R365-F467 HydrophobicContact CB-CZ 4.09Å; R365-F467 HydrophobicContact CG-CD2 4.15Å; R365-F467 HydrophobicContact CG-CE2 4.41Å; R365-F467 HydrophobicContact CG-CG 4.24Å; H465-F467 HydrophobicContact CB-CD1 4.01Å; H465-F467 HydrophobicContact CB-CE1 3.58Å; H465-F467 HydrophobicContact CB-CE2 4.26Å; H465-F467 HydrophobicContact CB-CZ 3.72Å; H465-F467 AromaticContact CG-CE1 3.94Å; H465-F467 AromaticContact ND1-CE1 3.89Å; H465-F467 PolarHBondContact O-N 2.99Å; F467-G469 PolarHBondContact O-N 3.13Å
468T72.6Confident79.3Confident6 Ų658.2 Ų58.24%0.03730%0.296CS..G310 helixtrans-75.7-17.217866.30000112W372 F462 H465 A466 L470W372-T468 HydrophobicContact CH2-CG2 3.64Å; W372-T468 HydrophobicContact CZ2-CG2 3.55Å; W372-T468 HydrophobicContact CZ3-CG2 4.3Å; F462-T468 WeakPolarHBondContact O-CG2 3.2Å; F462-T468 PolarHBondContact O-OG1 3.24Å; H465-T468 HydrophobicContact CB-CG2 3.93Å; H465-T468 PolarHBondContact O-N 3.16Å; H465-T468 PolarHBondContact O-OG1 3.36Å; A466-T468 PolarHBondContact O-N 3.3Å; T468-L470 PolarHBondContact O-N 2.89Å; T468-L470 VanDerWaalsContact O-N 3.09Å; T468-L470 PolarHBondContact OG1-N 2.84Å
469G73.8Confident79Confident8 Ų858.1 Ų58.18%0.08230%0.296CS..  trans65.57-176.700000114.4A466 F467 Q482A466-G469 PolarHBondContact O-N 3.23Å; F467-G469 PolarHBondContact O-N 3.13Å; G469-Q482 VanDerWaalsContact CA-OE1 3.31Å; G469-Q482 PolarHBondContact O-N 3.49Å
470L80.3Confident78.7Confident12 Ų1260 Ų606%0.06331%0.308CS..EExtended strand (participates in β ladder)trans-78.2137.8-175.8-61.8-178.1000111.8W372 V376 F462 M463 T468 V480W372-L470 HydrophobicContact CE3-CD1 3.73Å; W372-L470 HydrophobicContact CE3-CD2 4.35Å; W372-L470 HydrophobicContact CE3-CG 4.22Å; W372-L470 HydrophobicContact CZ3-CD1 3.75Å; V376-L470 HydrophobicContact CG2-CD2 3.15Å; V376-L470 HydrophobicContact CG2-CG 4.47Å; F462-L470 HydrophobicContact CB-CD1 4.14Å; M463-L470 HydrophobicContact CB-CB 4.4Å; M463-L470 HydrophobicContact CG-CB 3.49Å; M463-L470 VanDerWaalsContact CG-CB 3.49Å; M463-L470 HydrophobicContact CG-CD1 4.41Å; T468-L470 PolarHBondContact O-N 2.89Å; T468-L470 VanDerWaalsContact O-N 3.09Å; T468-L470 PolarHBondContact OG1-N 2.84Å; L470-V480 CarbonylContact C-O 3.58Å; L470-V480 WeakPolarHBondContact CA-O 3.46Å
471R81.9Confident77.9Confident155 Ų15559.8 Ų59.859%0.58531%0.308SS*.EExtended strand (participates in β ladder)trans-141.2158.5176.8-58-176-178.1-161.4-0.9110.4F479 V480R471-F479 CarbonylContact O-C 3.58Å; R471-F479 WeakPolarHBondContact O-CA 3.41Å; R471-V480 PolarHBondContact N-O 2.99Å; R471-V480 PolarHBondContact O-N 3.45Å
472I80.8Confident76.8Confident58 Ų5863.7 Ų63.730%0.29733%0.327SS..EExtended strand (participates in β ladder)trans-95.2127.5164.3-75.8164.5000108.7M463 N474 K478 F479M463-I472 HydrophobicContact CE-CD1 3.55Å; M463-I472 HydrophobicContact CE-CG1 3.9Å; M463-I472 HydrophobicContact SD-CD1 4Å; M463-I472 HydrophobicContact SD-CG1 3.64Å; I472-N474 PolarHBondContact O-N 3.04Å; I472-K478 WeakPolarHBondContact CA-O 3.23Å; I472-F479 HydrophobicContact CD1-CD1 4.5Å; I472-F479 HydrophobicContact CD1-CE1 4.1Å; I472-F479 HydrophobicContact CG1-CD1 3.94Å; I472-F479 HydrophobicContact CG1-CE1 4.05Å
473D81.6Confident75.2Confident53 Ų5368.2 Ų68.228%0.28335%0.351SS..EExtended strand (participates in β ladder)trans-76.6105.3162.4170.514.7000108.7S475 T476 L477 K478 V480D473-S475 VanDerWaalsContact CG-OG 3.25Å; D473-S475 PolarHBondContact O-N 2.7Å; D473-S475 VanDerWaalsContact O-N 3.13Å; D473-S475 WeakPolarHBondContact OD1-CB 3.34Å; D473-S475 PolarHBondContact OD1-N 2.96Å; D473-S475 PolarHBondContact OD1-OG 3.35Å; D473-S475 PolarHBondContact OD2-OG 3.11Å; D473-S475 VanDerWaalsContact OD2-OG 3.12Å; D473-T476 WeakPolarHBondContact CB-OG1 3.48Å; D473-T476 VanDerWaalsContact CG-OG1 3.23Å; D473-T476 PolarHBondContact O-N 2.96Å; D473-T476 VanDerWaalsContact O-N 3.13Å; D473-T476 WeakPolarHBondContact OD2-CB 3.37Å; D473-T476 WeakPolarHBondContact OD2-CG2 3.33Å; D473-T476 PolarHBondContact OD2-OG1 2.95Å; D473-L477 WeakPolarHBondContact O-CA 3.1Å; D473-L477 PolarHBondContact O-N 3.46Å; D473-K478 PolarHBondContact N-O 2.8Å; D473-V480 HydrophobicContact CB-CG2 3.74Å
474N72.3Confident73.3Confident137 Ų13770.3 Ų70.373%0.73337%0.369SS*.THydrogen-bonded Turntrans-60.2-22.2-178.6-69.3-30.9000113.3I472I472-N474 PolarHBondContact O-N 3.04Å
475S64Low70.8Confident88 Ų8866.8 Ų66.862%0.61537%0.371SS*.THydrogen-bonded Turntrans-78.4-30.6179.373.20000112.5D473D473-S475 VanDerWaalsContact CG-OG 3.25Å; D473-S475 PolarHBondContact O-N 2.7Å; D473-S475 VanDerWaalsContact O-N 3.13Å; D473-S475 WeakPolarHBondContact OD1-CB 3.34Å; D473-S475 PolarHBondContact OD1-N 2.96Å; D473-S475 PolarHBondContact OD1-OG 3.35Å; D473-S475 PolarHBondContact OD2-OG 3.11Å; D473-S475 VanDerWaalsContact OD2-OG 3.12Å
476T73.3Confident68.3Low30 Ų3070.3 Ų70.318%0.18439%0.392CS..THydrogen-bonded Turntrans-111.6-11.2-176.165.10000113.3M318 D473 K478M318-T476 HydrophobicContact CE-CG2 3.18Å; M318-T476 HydrophobicContact SD-CG2 3.49Å; M318-T476 WeakPolarHBondContact SD-CG2 3.34Å; D473-T476 WeakPolarHBondContact CB-OG1 3.48Å; D473-T476 VanDerWaalsContact CG-OG1 3.23Å; D473-T476 PolarHBondContact O-N 2.96Å; D473-T476 VanDerWaalsContact O-N 3.13Å; D473-T476 WeakPolarHBondContact OD2-CB 3.37Å; D473-T476 WeakPolarHBondContact OD2-CG2 3.33Å; D473-T476 PolarHBondContact OD2-OG1 2.95Å; T476-K478 PolarHBondContact O-N 3.22Å
477L71.1Confident66.3Low94 Ų9473.9 Ų73.949%0.49240%0.398SS..THydrogen-bonded Turntrans54.834-174.1-57.6171.6000112.2F386 D473F386-L477 HydrophobicContact CD2-CD1 4.45Å; F386-L477 HydrophobicContact CE2-CD1 3.81Å; D473-L477 WeakPolarHBondContact O-CA 3.1Å; D473-L477 PolarHBondContact O-N 3.46Å
478K82.2Confident64Low79 Ų7975.3 Ų75.334%0.34341%0.41SS..EExtended strand (participates in β ladder)trans-112.1151.6178.6-69.5-177.5-179.6179.10110.9N380 I472 D473 T476N380-K478 WeakPolarHBondContact OD1-CA 3.42Å; N380-K478 WeakPolarHBondContact OD1-CB 3.15Å; I472-K478 WeakPolarHBondContact CA-O 3.23Å; D473-K478 PolarHBondContact N-O 2.8Å; T476-K478 PolarHBondContact O-N 3.22Å
479F83Confident61.8Low5 Ų581.6 Ų81.62%0.02245%0.448CS..EExtended strand (participates in β ladder)trans-73.6143.6169.7-58.3-88.7000109.8V376 V379 N380 A459 H460 M463 R471 I472V376-F479 HydrophobicContact CG1-CB 3.94Å; V376-F479 WeakPolarHBondContact CG1-O 3.26Å; V376-F479 HydrophobicContact CG2-CB 4.3Å; V379-F479 HydrophobicContact CB-CD2 4.42Å; V379-F479 HydrophobicContact CG1-CD2 3.65Å; V379-F479 HydrophobicContact CG1-CE2 3.43Å; V379-F479 VanDerWaalsContact CG1-CE2 3.43Å; V379-F479 HydrophobicContact CG1-CZ 4.24Å; N380-F479 PolarHBondContact ND2-O 3.17Å; N380-F479 PolarHBondContact OD1-N 3.3Å; A459-F479 HydrophobicContact CB-CD1 4.12Å; A459-F479 HydrophobicContact CB-CE1 3.59Å; A459-F479 HydrophobicContact CB-CE2 4.12Å; A459-F479 HydrophobicContact CB-CZ 3.61Å; H460-F479 AromaticContact NE2-CZ 3.63Å; M463-F479 HydrophobicContact CE-CD1 3.91Å; M463-F479 HydrophobicContact CE-CE1 3.42Å; M463-F479 VanDerWaalsContact CE-CE1 3.42Å; M463-F479 HydrophobicContact CG-CD1 4.32Å; M463-F479 HydrophobicContact SD-CD1 3.56Å; M463-F479 VanDerWaalsContact SD-CD1 3.56Å; M463-F479 HydrophobicContact SD-CE1 3.76Å; R471-F479 CarbonylContact O-C 3.58Å; R471-F479 WeakPolarHBondContact O-CA 3.41Å; I472-F479 HydrophobicContact CD1-CD1 4.5Å; I472-F479 HydrophobicContact CD1-CE1 4.1Å; I472-F479 HydrophobicContact CG1-CD1 3.94Å; I472-F479 HydrophobicContact CG1-CE1 4.05Å
480V82Confident59.8Low42 Ų4288.7 Ų88.726%0.25548%0.481SS..EExtended strand (participates in β ladder)trans-137.7143.5-178.8-174.90000108.5L470 R471 D473 S484L470-V480 CarbonylContact C-O 3.58Å; L470-V480 WeakPolarHBondContact CA-O 3.46Å; R471-V480 PolarHBondContact N-O 2.99Å; R471-V480 PolarHBondContact O-N 3.45Å; D473-V480 HydrophobicContact CB-CG2 3.74Å; V480-S484 WeakPolarHBondContact CG1-OG 2.94Å
481S72.2Confident57.3Low19 Ų1997.1 Ų97.113%0.13352%0.517CS..EExtended strand (participates in β ladder)trans-99.3148.3173.1175.30000110.4D483 S484S481-D483 PolarHBondContact O-N 2.85Å; S481-S484 PolarHBondContact O-N 3.46Å; S481-S484 PolarHBondContact O-OG 3Å
482Q62.3Low54.9Low103 Ų10397.1 Ų97.148%0.48153%0.528SS..THydrogen-bonded Turntrans-57.6-19.3-172.9-112.2176.3-29.500115.6G469 S484G469-Q482 VanDerWaalsContact CA-OE1 3.31Å; G469-Q482 PolarHBondContact O-N 3.49Å; Q482-S484 VanDerWaalsContact C-N 3.32Å; Q482-S484 PolarHBondContact O-N 3.22Å
483D54.8Low52.3Low97 Ų9798.7 Ų98.752%0.51954%0.542SS..THydrogen-bonded Turntrans-84.12.4-177.6-65.2-34.4000114.7N313 S481 S485N313-D483 VanDerWaalsContact ND2-CB 3.25Å; N313-D483 WeakPolarHBondContact ND2-CB 3.19Å; N313-D483 PolarHBondContact ND2-OD2 3.06Å; S481-D483 PolarHBondContact O-N 2.85Å; D483-S485 PolarHBondContact O-N 3.08Å
484S44.2Very low49.8Very low79 Ų79103.7 Ų103.755%0.55257%0.568SS**THydrogen-bonded Turntrans-81.610.1-176740000115.1V480 S481 Q482V480-S484 WeakPolarHBondContact CG1-OG 2.94Å; S481-S484 PolarHBondContact O-N 3.46Å; S481-S484 PolarHBondContact O-OG 3Å; Q482-S484 VanDerWaalsContact C-N 3.32Å; Q482-S484 PolarHBondContact O-N 3.22Å
485S30.5Very low47.8Very low96 Ų96103.8 Ų103.867%0.67157%0.568SS**THydrogen-bonded Turntrans-100.80.1-169.368.70000116.8D483D483-S485 PolarHBondContact O-N 3.08Å
486N28.2Very low46Very low145 Ų145103.8 Ų103.878%0.77557%0.568SS**SBendtrans-127.5120.9178.8-74.9-15.2000113.2
487D28.2Very low43.7Very low167 Ų167107.9 Ų107.989%0.89359%0.594SS**  trans73.9134.4155.7-103-23000122.3
488D25.9Very low41.7Very low109 Ų109111.3 Ų111.358%0.58361%0.61SS**  trans-69.4163.2-179-77.7-52.8000112.6K317K317-D488 IonicContact NZ-OD1 2.96Å; K317-D488 PolarHBondContact NZ-OD1 3.41Å
489T25.1Very low39.2Very low138 Ų138116.8 Ų116.885%0.84763%0.634SS**  trans68.496.7172.644.20000118.4
490M31.7Very low36.5Very low156 Ų156123.9 Ų123.977%0.76867%0.672SS**  trans-155.6132.7145.9-112.7-178.9-168.600114.6I314I314-M490 HydrophobicContact CG2-CB 4.23Å
491K27.9Very low33.9Very low190 Ų190127.4 Ų127.483%0.82670%0.699SS**  trans-69.8147178.3-65.2165.9173.9174.50110.5P493K491-P493 WeakPolarHBondContact O-CD 3.41Å
492L31.3Very low31.9Very low155 Ų155134.7 Ų134.781%0.81273%0.731SS**  trans-58.8125.6167.3-121.393.9000109L494L492-L494 PolarHBondContact O-N 2.96Å; L492-L494 VanDerWaalsContact O-N 3.14Å
493P26.9Very low30.2Very low91 Ų91139.3 Ų139.359%0.59175%0.749SS**  trans-73.2106162.90.616.4000106.8I314 K491 L495I314-P493 HydrophobicContact CD1-CG 3.93Å; K491-P493 WeakPolarHBondContact O-CD 3.41Å; P493-L495 PolarHBondContact O-N 3.07Å
494L28.1Very low29Very low158 Ų158141.5 Ų141.583%0.82776%0.76SS**  trans-49123148.6-80.2155.7000105.9L492 S496L492-L494 PolarHBondContact O-N 2.96Å; L492-L494 VanDerWaalsContact O-N 3.14Å; L494-S496 PolarHBondContact O-N 3.38Å
495L31.6Very low28.3Very low139 Ų139143.2 Ų143.273%0.72877%0.769SS**  trans-52.397.3165.5-94.2153.4000106.4P493P493-L495 PolarHBondContact O-N 3.07Å
496S24.7Very low28.3Very low88 Ų88144.7 Ų144.762%0.61577%0.769SS**  trans-60.3135.4166.644.60000105.5L494 M498L494-S496 PolarHBondContact O-N 3.38Å; S496-M498 PolarHBondContact O-N 3.38Å
497P26.9Very low28.3Very low115 Ų115144.8 Ų144.875%0.74777%0.769SS**  trans-58.6111.1176.923.7-30.4000106.1K499P497-K499 VanDerWaalsContact C-N 3.29Å; P497-K499 PolarHBondContact O-N 2.94Å
498M29.1Very low28.3Very low166 Ų166144.4 Ų144.482%0.81877%0.767SS**  trans-56.9101.5174.4-90.8-172117.500106.5S496 N500S496-M498 PolarHBondContact O-N 3.38Å; M498-N500 PolarHBondContact O-N 3.28Å
499K29.1Very low28.4Very low194 Ų194145.2 Ų145.284%0.84377%0.77SS**  trans-63.3132.4167.2-77-179.3176.9177.60106.3P497P497-K499 VanDerWaalsContact C-N 3.29Å; P497-K499 PolarHBondContact O-N 2.94Å
500N26.6Very low28.6Very low154 Ų154142.9 Ų142.982%0.82477%0.765SS**SBendtrans-20.7134.1173-62.1-27.1000115.6M498M498-N500 PolarHBondContact O-N 3.28Å
501S27.1Very low28.4Very low117 Ų117144 Ų14482%0.81877%0.768SS**  trans61.877.9158.872.80000117.2
502E29.6Very low28.7Very low172 Ų172139.7 Ų139.780%0.80475%0.754SS**  trans-117.7115.3144.2-87.3-177.9161.800108.2L504E502-L504 PolarHBondContact O-N 3.07Å
503K27.6Very low28.9Very low200 Ų200132.6 Ų132.687%0.8772%0.718SS**  trans-59.9115.6173.7-69.4176.1175.7-1790107.6
504L29.4Very low29.8Very low143 Ų143131.6 Ų131.675%0.74971%0.708SS**  trans-59145.7163.7-99.7105.6000109E502 L506E502-L504 PolarHBondContact O-N 3.07Å; L504-L506 PolarHBondContact O-N 3.12Å
505P29.1Very low30.8Very low114 Ų114125.5 Ų125.574%0.7468%0.676SS**  trans-58.6122.4-180-16.529000110.1D507P505-D507 PolarHBondContact O-N 2.89Å
506L29.3Very low32.1Very low127 Ų127119.1 Ų119.167%0.66564%0.643SS**G310 helixtrans-72.5-1.2-174.5-101.4107.3000114.7L504 N508L504-L506 PolarHBondContact O-N 3.12Å; L506-N508 PolarHBondContact O-N 3.32Å
507D29.8Very low33.7Very low147 Ų147115.3 Ų115.379%0.78662%0.615SS**G310 helixtrans-93.96.8-160.6-64.3-26.3000115.4P505P505-D507 PolarHBondContact O-N 2.89Å
508N27.9Very low35.4Very low159 Ų159111.1 Ų111.185%0.8559%0.589SS**G310 helixtrans-124.420177.6-79.8-18.6000114.4L506 A510L506-N508 PolarHBondContact O-N 3.32Å; N508-A510 PolarHBondContact O-N 3.42Å
509I28.1Very low37.1Very low127 Ų127105.6 Ų105.665%0.65156%0.561SS**  trans-75.882.2171.8-54.1176.3000107.6H511I509-H511 PolarHBondContact O-N 3.41Å
510A28.5Very low38.5Very low88 Ų8896.4 Ų96.473%0.72752%0.521SS*.  trans-57.9126.7166.800000108.3N508 D512N508-A510 PolarHBondContact O-N 3.42Å; A510-D512 PolarHBondContact O-N 2.69Å
511H28.8Very low40.4Very low180 Ų18089.4 Ų89.483%0.83348%0.483SS*.SBendtrans-6291.4176-68.7-77.3000111I509I509-H511 PolarHBondContact O-N 3.41Å
512D34.2Very low42.4Very low99 Ų9985.6 Ų85.653%0.52945%0.453SS..SBendtrans-171.3138.8151.1-101.8-30.3000110.9I304 A510 D514I304-D512 HydrophobicContact CG1-CB 4.25Å; I304-D512 HydrophobicContact CG2-CB 4.14Å; A510-D512 PolarHBondContact O-N 2.69Å; D512-D514 VanDerWaalsContact C-N 3.34Å; D512-D514 PolarHBondContact O-N 2.9Å
513G33.9Very low44.3Very low7 Ų778.8 Ų78.87%0.07242%0.421CS..  trans-76.869.1-168.800000114.9I304 L515I304-G513 WeakPolarHBondContact CG2-O 3.26Å; G513-L515 PolarHBondContact O-N 2.81Å
514D46.7Very low45.8Very low69 Ų6969.3 Ų69.337%0.36938%0.379SS..  trans-47.5125.8-175.5-70.7-25000113.6V248 D512 Q516V248-D514 WeakPolarHBondContact CG1-O 3.3Å; D512-D514 VanDerWaalsContact C-N 3.34Å; D512-D514 PolarHBondContact O-N 2.9Å; D514-Q516 PolarHBondContact O-N 2.99Å
515L49.8Very low47.9Very low30 Ų3062.5 Ų62.516%0.15734%0.344CS..  trans-72130.7176.2-127.7111.3000110.5L232 Q287 I291 G513 I517L232-L515 HydrophobicContact CD1-CD1 3.65Å; L232-L515 HydrophobicContact CD1-CG 4.46Å; Q287-L515 HydrophobicContact CB-CD2 3.63Å; Q287-L515 HydrophobicContact CG-CD2 3.85Å; I291-L515 HydrophobicContact CD1-CD2 3.85Å; I291-L515 HydrophobicContact CG1-CD1 4.39Å; I291-L515 HydrophobicContact CG1-CD2 3.77Å; G513-L515 PolarHBondContact O-N 2.81Å; L515-I517 HydrophobicContact CD2-CD1 4.48Å; L515-I517 HydrophobicContact CD2-CG1 4.48Å; L515-I517 PolarHBondContact O-N 3.43Å
516Q58.4Low49.9Very low6 Ų658.5 Ų58.53%0.02832%0.319CS..THydrogen-bonded Turntrans-65.34.7-164.1-59.9152.7-1.100117.1V248 N251 I252 D514 S518 Q519 V520V248-Q516 HydrophobicContact CG1-CG 4.48Å; N251-Q516 PolarHBondContact OD1-NE2 3.43Å; N251-Q516 PolarHBondContact OD1-OE1 2.83Å; I252-Q516 HydrophobicContact CD1-CG 4.42Å; I252-Q516 HydrophobicContact CG1-CG 3.94Å; D514-Q516 PolarHBondContact O-N 2.99Å; Q516-S518 VanDerWaalsContact C-N 3.31Å; Q516-S518 PolarHBondContact O-N 3.21Å; Q516-Q519 PolarHBondContact O-N 3.39Å; Q516-V520 WeakPolarHBondContact O-CG2 3.31Å; Q516-V520 PolarHBondContact O-N 3.2Å
517I58.5Low51.6Low8 Ų852.6 Ų52.64%0.04129%0.288CS..Hα-helixtrans-59.3-44.7-173.5-63.5178.2000110.3Q287 M288 I291 W356 L515 Q519 V520 I521Q287-I517 HydrophobicContact CB-CD1 3.96Å; Q287-I517 HydrophobicContact CB-CG1 3.85Å; Q287-I517 HydrophobicContact CG-CG1 4.47Å; M288-I517 HydrophobicContact CG-CD1 4.45Å; I291-I517 HydrophobicContact CD1-CD1 3.45Å; I291-I517 VanDerWaalsContact CD1-CD1 3.45Å; W356-I517 HydrophobicContact CE3-CG2 4.35Å; W356-I517 HydrophobicContact CH2-CD1 3.68Å; W356-I517 HydrophobicContact CH2-CG2 4.44Å; W356-I517 HydrophobicContact CZ2-CD1 3.98Å; W356-I517 HydrophobicContact CZ3-CD1 4.07Å; W356-I517 HydrophobicContact CZ3-CG2 3.86Å; L515-I517 HydrophobicContact CD2-CD1 4.48Å; L515-I517 HydrophobicContact CD2-CG1 4.48Å; L515-I517 PolarHBondContact O-N 3.43Å; I517-Q519 VanDerWaalsContact C-N 3.3Å; I517-Q519 PolarHBondContact O-N 3.18Å; I517-V520 PolarHBondContact O-N 3.33Å; I517-V520 VanDerWaalsContact O-N 3.15Å; I517-I521 HydrophobicContact CG2-CD1 3.87Å; I517-I521 HydrophobicContact CG2-CG1 4.25Å; I517-I521 WeakPolarHBondContact O-CG1 3.41Å; I517-I521 PolarHBondContact O-N 2.99Å
518S61.6Low53.3Low27 Ų2745.6 Ų45.619%0.18925%0.25CS..Hα-helixtrans-53.3-44.7177.653.70000113.5Q516 I521 E522Q516-S518 VanDerWaalsContact C-N 3.31Å; Q516-S518 PolarHBondContact O-N 3.21Å; S518-I521 WeakPolarHBondContact O-CB 3.47Å; S518-I521 PolarHBondContact O-N 3.09Å; S518-E522 PolarHBondContact O-N 2.99Å
519Q64.9Low55.3Low50 Ų5038.7 Ų38.723%0.23421%0.214CC..Hα-helixtrans-73.5-38.8179.3-64.9-175.2-7.300111.5I252 Q516 I517 I521 E522 H523I252-Q519 VanDerWaalsContact CD1-OE1 3.32Å; Q516-Q519 PolarHBondContact O-N 3.39Å; I517-Q519 VanDerWaalsContact C-N 3.3Å; I517-Q519 PolarHBondContact O-N 3.18Å; Q519-I521 PolarHBondContact O-N 2.92Å; Q519-E522 PolarHBondContact O-N 3.47Å; Q519-H523 PolarHBondContact O-N 2.89Å; Q519-H523 PolarHBondContact O-ND1 2.86Å
520V58.1Low57.2Low0 Ų035 Ų350%020%0.195CC..Hα-helixtrans-57.5-41.6171.4176.10000110.1L255 I280 L283 V284 I353 Q516 I517 H523 V524L255-V520 HydrophobicContact CD2-CG2 3.75Å; I280-V520 HydrophobicContact CG2-CG1 3.81Å; L283-V520 HydrophobicContact CD2-CG2 4.43Å; V284-V520 HydrophobicContact CG2-CG1 3.75Å; I353-V520 HydrophobicContact CD1-CG1 4.4Å; Q516-V520 WeakPolarHBondContact O-CG2 3.31Å; Q516-V520 PolarHBondContact O-N 3.2Å; I517-V520 PolarHBondContact O-N 3.33Å; I517-V520 VanDerWaalsContact O-N 3.15Å; V520-H523 PolarHBondContact O-N 3.4Å; V520-V524 HydrophobicContact CG1-CG2 4.08Å; V520-V524 WeakPolarHBondContact O-CB 3.43Å; V520-V524 WeakPolarHBondContact O-CG2 3.46Å; V520-V524 PolarHBondContact O-N 2.96Å
521I67.5Low58.9Low7 Ų733.4 Ų33.44%0.03617%0.173CC..Hα-helixtrans-58.3-53175.1-64.4167.2000110.6I353 L357 M367 I517 S518 Q519 H523 V524 L525I353-I521 HydrophobicContact CD1-CG1 4.02Å; I353-I521 HydrophobicContact CG1-CG1 4.44Å; I353-I521 HydrophobicContact CG2-CD1 3.87Å; I353-I521 HydrophobicContact CG2-CG1 3.54Å; L357-I521 HydrophobicContact CD1-CD1 4.13Å; L357-I521 HydrophobicContact CD2-CD1 4.25Å; M367-I521 HydrophobicContact CE-CG2 4.02Å; I517-I521 HydrophobicContact CG2-CD1 3.87Å; I517-I521 HydrophobicContact CG2-CG1 4.25Å; I517-I521 WeakPolarHBondContact O-CG1 3.41Å; I517-I521 PolarHBondContact O-N 2.99Å; S518-I521 WeakPolarHBondContact O-CB 3.47Å; S518-I521 PolarHBondContact O-N 3.09Å; Q519-I521 PolarHBondContact O-N 2.92Å; I521-H523 VanDerWaalsContact C-N 3.33Å; I521-H523 PolarHBondContact O-N 3.21Å; I521-V524 PolarHBondContact O-N 2.95Å; I521-L525 HydrophobicContact CG2-CD1 3.78Å; I521-L525 HydrophobicContact CG2-CG 4.26Å; I521-L525 WeakPolarHBondContact O-CB 3.34Å; I521-L525 VanDerWaalsContact O-CG 3.26Å; I521-L525 WeakPolarHBondContact O-CG 3.5Å; I521-L525 PolarHBondContact O-N 3.23Å
522E69Low60.6Low38 Ų3825 Ų2518%0.17813%0.134CC..Hα-helixtrans-57.6-44.5-179.4-76.6-171.3176.600112.5S371 S518 Q519 L525 S526S371-E522 VanDerWaalsContact OG-CG 3.25Å; S371-E522 WeakPolarHBondContact OG-CG 3.47Å; S371-E522 PolarHBondContact OG-OE1 3.43Å; S518-E522 PolarHBondContact O-N 2.99Å; Q519-E522 PolarHBondContact O-N 3.47Å; E522-L525 PolarHBondContact O-N 3Å; E522-S526 WeakPolarHBondContact O-CB 3.32Å; E522-S526 PolarHBondContact O-N 3.29Å
523H68.9Low62.2Low29 Ų2924.1 Ų24.113%0.13413%0.127CC..Hα-helixtrans-68.9-42.3179.7-73.493.4000113N256 F259 Q519 V520 I521 L525 S526 I527N256-H523 PolarHBondContact OD1-CE1 2.96Å; N256-H523 PolarHBondContact OD1-NE2 3.15Å; F259-H523 HydrophobicContact CB-CB 4.33Å; F259-H523 VanDerWaalsContact CB-CD2 3.47Å; F259-H523 WeakPolarHBondContact CB-CD2 3.47Å; F259-H523 HydrophobicContact CD1-CB 3.65Å; F259-H523 HydrophobicContact CD2-CB 3.39Å; F259-H523 AromaticContact CD2-CD2 3.61Å; F259-H523 AromaticContact CD2-CG 3.4Å; F259-H523 HydrophobicContact CE1-CB 3.7Å; F259-H523 HydrophobicContact CE2-CB 3.37Å; F259-H523 AromaticContact CE2-CG 3.79Å; F259-H523 HydrophobicContact CG-CB 3.55Å; F259-H523 AromaticContact CG-CD2 3.61Å; F259-H523 AromaticContact CG-CG 3.71Å; F259-H523 HydrophobicContact CZ-CB 3.58Å; Q519-H523 PolarHBondContact O-N 2.89Å; Q519-H523 PolarHBondContact O-ND1 2.86Å; V520-H523 PolarHBondContact O-N 3.4Å; I521-H523 VanDerWaalsContact C-N 3.33Å; I521-H523 PolarHBondContact O-N 3.21Å; H523-L525 VanDerWaalsContact C-N 3.33Å; H523-S526 PolarHBondContact O-N 3.44Å; H523-I527 PolarHBondContact O-N 3.49Å
524V59.5Low63.5Low0 Ų028.1 Ų28.10%014%0.143CC..Hα-helixtrans-62.4-43.7175.8170.20000110F259 W346 V349 L350 V520 I521 S526 L528F259-V524 HydrophobicContact CZ-CG2 4.34Å; W346-V524 HydrophobicContact CE3-CG2 4.1Å; W346-V524 HydrophobicContact CZ3-CG2 4.19Å; V349-V524 HydrophobicContact CB-CG1 4.29Å; V349-V524 HydrophobicContact CG1-CG1 4.29Å; V349-V524 HydrophobicContact CG1-CG2 3.82Å; L350-V524 HydrophobicContact CB-CG1 4.17Å; V520-V524 HydrophobicContact CG1-CG2 4.08Å; V520-V524 WeakPolarHBondContact O-CB 3.43Å; V520-V524 WeakPolarHBondContact O-CG2 3.46Å; V520-V524 PolarHBondContact O-N 2.96Å; I521-V524 PolarHBondContact O-N 2.95Å; V524-S526 VanDerWaalsContact C-N 3.33Å; V524-S526 PolarHBondContact O-N 2.97Å; V524-L528 HydrophobicContact CG1-CD1 3.78Å; V524-L528 HydrophobicContact CG1-CG 4.43Å; V524-L528 VanDerWaalsContact O-CB 3.3Å; V524-L528 WeakPolarHBondContact O-CB 3.36Å; V524-L528 VanDerWaalsContact O-CG 3.24Å; V524-L528 WeakPolarHBondContact O-CG 2.78Å; V524-L528 PolarHBondContact O-N 2.98Å
525L73.2Confident64.2Low1 Ų128.4 Ų28.41%0.00514%0.139CC..Hα-helixtrans-61.5-40.5174-71.4176.4000111.6L350 R374 F375 I521 E522 H523 T529L350-L525 HydrophobicContact CD1-CD2 3.68Å; L350-L525 HydrophobicContact CD1-CG 4.38Å; L350-L525 HydrophobicContact CD2-CD2 4.12Å; R374-L525 HydrophobicContact CB-CB 4.13Å; R374-L525 HydrophobicContact CB-CD1 4.36Å; F375-L525 HydrophobicContact CB-CD1 4.24Å; F375-L525 HydrophobicContact CB-CD2 4.26Å; F375-L525 HydrophobicContact CD2-CD2 4.11Å; I521-L525 HydrophobicContact CG2-CD1 3.78Å; I521-L525 HydrophobicContact CG2-CG 4.26Å; I521-L525 WeakPolarHBondContact O-CB 3.34Å; I521-L525 VanDerWaalsContact O-CG 3.26Å; I521-L525 WeakPolarHBondContact O-CG 3.5Å; I521-L525 PolarHBondContact O-N 3.23Å; E522-L525 PolarHBondContact O-N 3Å; H523-L525 VanDerWaalsContact C-N 3.33Å; L525-T529 WeakPolarHBondContact O-CB 3.29Å; L525-T529 PolarHBondContact O-N 3.24Å; L525-T529 PolarHBondContact O-OG1 3.06Å
526S70.7Confident64.7Low30 Ų3032 Ų3221%0.2115%0.154CC..Hα-helixtrans-65.4-51.5177.7-165.50000112.1E522 H523 V524 L528 T529 D530E522-S526 WeakPolarHBondContact O-CB 3.32Å; E522-S526 PolarHBondContact O-N 3.29Å; H523-S526 PolarHBondContact O-N 3.44Å; V524-S526 VanDerWaalsContact C-N 3.33Å; V524-S526 PolarHBondContact O-N 2.97Å; S526-L528 VanDerWaalsContact C-N 3.29Å; S526-L528 PolarHBondContact O-N 3.22Å; S526-T529 PolarHBondContact O-N 2.9Å; S526-D530 VanDerWaalsContact O-CB 3.32Å; S526-D530 WeakPolarHBondContact O-CB 3.14Å; S526-D530 PolarHBondContact O-N 3.37Å
527I65.5Low64.7Low3 Ų334 Ų342%0.01517%0.172CC..Hα-helixtrans-51.8-53.5174.8-74.9-174.3000109.4F259 L262 L263 W346 H523 D530 Q531F259-I527 HydrophobicContact CD1-CD1 3.35Å; F259-I527 HydrophobicContact CD1-CG1 3.82Å; F259-I527 HydrophobicContact CE1-CD1 3.42Å; F259-I527 VanDerWaalsContact CE1-CD1 3.42Å; F259-I527 HydrophobicContact CE1-CG1 4.16Å; L262-I527 HydrophobicContact CB-CD1 4.26Å; L262-I527 HydrophobicContact CD1-CD1 4.05Å; L263-I527 HydrophobicContact CD2-CB 4.13Å; L263-I527 HydrophobicContact CD2-CG1 3.5Å; W346-I527 HydrophobicContact CD2-CD1 4.08Å; W346-I527 HydrophobicContact CD2-CG2 4.32Å; W346-I527 HydrophobicContact CE3-CD1 4.41Å; W346-I527 HydrophobicContact CG-CG2 3.97Å; W346-I527 HydrophobicContact CH2-CD1 4.01Å; W346-I527 HydrophobicContact CZ2-CD1 3.65Å; W346-I527 HydrophobicContact CZ3-CD1 4.37Å; H523-I527 PolarHBondContact O-N 3.49Å; I527-D530 PolarHBondContact O-N 3.13Å; I527-Q531 HydrophobicContact CG2-CG 4.12Å; I527-Q531 WeakPolarHBondContact O-CB 3.45Å; I527-Q531 VanDerWaalsContact O-CG 3.27Å; I527-Q531 WeakPolarHBondContact O-CG 3.26Å; I527-Q531 PolarHBondContact O-N 2.98Å
528L66.3Low64.3Low0 Ų035.6 Ų35.60%019%0.19CC..Hα-helixtrans-65.2-45.4-172.1-77.2170.6000111.6I344 W346 L347 L350 L378 V524 S526 D530 Q531 L532I344-L528 HydrophobicContact CG2-CD2 3.31Å; W346-L528 HydrophobicContact CB-CD1 4.32Å; W346-L528 HydrophobicContact CB-CD2 3.41Å; W346-L528 VanDerWaalsContact CB-CD2 3.41Å; W346-L528 HydrophobicContact CB-CG 3.74Å; L347-L528 HydrophobicContact CD2-CD1 4.42Å; L347-L528 HydrophobicContact CD2-CD2 3.85Å; L347-L528 HydrophobicContact CG-CD2 4.09Å; L350-L528 HydrophobicContact CB-CD1 3.85Å; L350-L528 HydrophobicContact CD2-CD1 3.81Å; L350-L528 HydrophobicContact CG-CD1 4.41Å; L378-L528 HydrophobicContact CD1-CB 3.21Å; L378-L528 HydrophobicContact CD1-CD1 3.89Å; L378-L528 HydrophobicContact CD1-CG 4.1Å; V524-L528 HydrophobicContact CG1-CD1 3.78Å; V524-L528 HydrophobicContact CG1-CG 4.43Å; V524-L528 VanDerWaalsContact O-CB 3.3Å; V524-L528 WeakPolarHBondContact O-CB 3.36Å; V524-L528 VanDerWaalsContact O-CG 3.24Å; V524-L528 WeakPolarHBondContact O-CG 2.78Å; V524-L528 PolarHBondContact O-N 2.98Å; S526-L528 VanDerWaalsContact C-N 3.29Å; S526-L528 PolarHBondContact O-N 3.22Å; L528-D530 VanDerWaalsContact C-N 3.31Å; L528-D530 PolarHBondContact O-N 3.41Å; L528-Q531 PolarHBondContact O-N 3.02Å; L528-L532 WeakPolarHBondContact O-CB 3.41Å; L528-L532 WeakPolarHBondContact O-CG 3.42Å; L528-L532 PolarHBondContact O-N 2.8Å
529T70Confident63.7Low13 Ų1336.2 Ų36.28%0.0819%0.19CC..Hα-helixtrans-60.2-45.4179-59.10000110.4L525 S526 L532 H533L525-T529 WeakPolarHBondContact O-CB 3.29Å; L525-T529 PolarHBondContact O-N 3.24Å; L525-T529 PolarHBondContact O-OG1 3.06Å; S526-T529 PolarHBondContact O-N 2.9Å; T529-L532 PolarHBondContact O-N 3.36Å; T529-H533 VanDerWaalsContact CG2-CD2 3.41Å; T529-H533 WeakPolarHBondContact CG2-CD2 3.11Å; T529-H533 WeakPolarHBondContact O-CB 3.29Å; T529-H533 PolarHBondContact O-CD2 3.23Å; T529-H533 PolarHBondContact O-N 3.03Å
530D67.8Low63Low49 Ų4937.8 Ų37.826%0.26220%0.2SC..Hα-helixtrans-67.3-45.6179.9-71.4-9.3000112.5R266 S526 I527 L528 L532 H533 E534R266-D530 VanDerWaalsContact CZ-CB 3.46Å; R266-D530 IonicContact CZ-OD2 3.31Å; R266-D530 IonicContact NH1-OD2 2.67Å; R266-D530 VanDerWaalsContact NH2-CG 3.35Å; R266-D530 IonicContact NH2-OD2 2.7Å; R266-D530 PolarHBondContact NH2-OD2 3.08Å; S526-D530 VanDerWaalsContact O-CB 3.32Å; S526-D530 WeakPolarHBondContact O-CB 3.14Å; S526-D530 PolarHBondContact O-N 3.37Å; I527-D530 PolarHBondContact O-N 3.13Å; L528-D530 VanDerWaalsContact C-N 3.31Å; L528-D530 PolarHBondContact O-N 3.41Å; D530-L532 PolarHBondContact O-N 3.24Å; D530-H533 PolarHBondContact O-N 3.01Å; D530-E534 WeakPolarHBondContact O-CB 2.91Å; D530-E534 WeakPolarHBondContact O-CG 3.21Å; D530-E534 PolarHBondContact O-N 2.87Å
531Q64.5Low62.3Low55 Ų5539.7 Ų39.726%0.25721%0.213SC..Hα-helixtrans-58.7-38.9175.6-76.9-177.6-20.700111.5I344 I527 L528 W535I344-Q531 HydrophobicContact CD1-CB 4.47Å; I527-Q531 HydrophobicContact CG2-CG 4.12Å; I527-Q531 WeakPolarHBondContact O-CB 3.45Å; I527-Q531 VanDerWaalsContact O-CG 3.27Å; I527-Q531 WeakPolarHBondContact O-CG 3.26Å; I527-Q531 PolarHBondContact O-N 2.98Å; L528-Q531 PolarHBondContact O-N 3.02Å; Q531-W535 WeakPolarHBondContact O-CB 3.31Å; Q531-W535 PolarHBondContact O-N 2.85Å
532L63.3Low61.1Low3 Ų340.2 Ų40.22%0.01622%0.219CC..Hα-helixtrans-73.5-37.6177.4-68.8175.8000112.7L341 I344 L378 L381 L382 L528 T529 D530 K536L341-L532 HydrophobicContact CD2-CD2 3.32Å; I344-L532 HydrophobicContact CD1-CD2 3.59Å; I344-L532 HydrophobicContact CD1-CG 4.29Å; L378-L532 HydrophobicContact CD1-CD1 3.9Å; L378-L532 HydrophobicContact CG-CD1 4.3Å; L381-L532 HydrophobicContact CB-CB 4.27Å; L381-L532 HydrophobicContact CB-CD1 3.94Å; L381-L532 HydrophobicContact CD1-CB 3.69Å; L381-L532 HydrophobicContact CD1-CD1 4.3Å; L382-L532 HydrophobicContact CD2-CD1 4.44Å; L528-L532 WeakPolarHBondContact O-CB 3.41Å; L528-L532 WeakPolarHBondContact O-CG 3.42Å; L528-L532 PolarHBondContact O-N 2.8Å; T529-L532 PolarHBondContact O-N 3.36Å; D530-L532 PolarHBondContact O-N 3.24Å; L532-K536 VanDerWaalsContact O-CB 3.24Å; L532-K536 WeakPolarHBondContact O-CB 3.32Å; L532-K536 PolarHBondContact O-N 2.92Å
533H67.4Low60Low82 Ų8244.1 Ų44.138%0.3823%0.232SC..Hα-helixtrans-66.4-44.8175-83-62.2000111.8T529 D530 K536 A537T529-H533 VanDerWaalsContact CG2-CD2 3.41Å; T529-H533 WeakPolarHBondContact CG2-CD2 3.11Å; T529-H533 WeakPolarHBondContact O-CB 3.29Å; T529-H533 PolarHBondContact O-CD2 3.23Å; T529-H533 PolarHBondContact O-N 3.03Å; D530-H533 PolarHBondContact O-N 3.01Å; H533-K536 PolarHBondContact O-N 3.41Å; H533-A537 WeakPolarHBondContact O-CB 3.33Å; H533-A537 PolarHBondContact O-N 3.36Å
534E62.5Low58.9Low90 Ų9047.7 Ų47.742%0.42125%0.248SC..Hα-helixtrans-62.3-44.1174-76.8-179.8-174.300111.5R266 D530 K536 A537 G538R266-E534 WeakPolarHBondContact CD-OE1 3.22Å; R266-E534 VanDerWaalsContact CD-OE2 3.3Å; R266-E534 WeakPolarHBondContact CD-OE2 3.31Å; R266-E534 IonicContact CZ-OE1 2.71Å; R266-E534 IonicContact NE-OE1 3.74Å; R266-E534 IonicContact NH1-OE1 3.5Å; R266-E534 PolarHBondContact NH1-OE1 3.14Å; D530-E534 WeakPolarHBondContact O-CB 2.91Å; D530-E534 WeakPolarHBondContact O-CG 3.21Å; D530-E534 PolarHBondContact O-N 2.87Å; E534-K536 VanDerWaalsContact C-N 3.31Å; E534-K536 PolarHBondContact O-N 3.39Å; E534-A537 PolarHBondContact O-N 3.2Å; E534-G538 PolarHBondContact O-N 2.89Å
535W60.2Low58.1Low75 Ų7548.2 Ų48.228%0.28425%0.252SS..Hα-helixtrans-60.6-42.8175178.579.8000111.7K337 A340 Q531 G538 M539K337-W535 VanDerWaalsContact CA-CH2 3.44Å; K337-W535 HydrophobicContact CB-CH2 3.45Å; K337-W535 VanDerWaalsContact CB-CH2 3.45Å; K337-W535 HydrophobicContact CB-CZ2 4.09Å; K337-W535 HydrophobicContact CB-CZ3 4.26Å; K337-W535 HydrophobicContact CD-CH2 4.14Å; K337-W535 HydrophobicContact CD-CZ3 4.18Å; K337-W535 HydrophobicContact CG-CH2 3.43Å; K337-W535 VanDerWaalsContact CG-CH2 3.43Å; K337-W535 HydrophobicContact CG-CZ2 4.34Å; K337-W535 HydrophobicContact CG-CZ3 3.74Å; A340-W535 HydrophobicContact CB-CD2 4.22Å; A340-W535 HydrophobicContact CB-CG 4.4Å; A340-W535 HydrophobicContact CB-CZ2 3.73Å; Q531-W535 WeakPolarHBondContact O-CB 3.31Å; Q531-W535 PolarHBondContact O-N 2.85Å; W535-G538 PolarHBondContact O-N 3.02Å; W535-M539 HydrophobicContact CD2-CG 4.2Å; W535-M539 HydrophobicContact CD2-SD 4.36Å; W535-M539 HydrophobicContact CE3-SD 4.35Å; W535-M539 HydrophobicContact CH2-CG 4.15Å; W535-M539 HydrophobicContact CH2-SD 3.08Å; W535-M539 WeakPolarHBondContact CH2-SD 3.33Å; W535-M539 HydrophobicContact CZ2-CE 4.5Å; W535-M539 HydrophobicContact CZ2-CG 3.84Å; W535-M539 HydrophobicContact CZ2-SD 3.1Å; W535-M539 WeakPolarHBondContact CZ2-SD 3.33Å; W535-M539 HydrophobicContact CZ3-CG 4.48Å; W535-M539 HydrophobicContact CZ3-SD 3.76Å; W535-M539 WeakPolarHBondContact O-CB 3.48Å; W535-M539 WeakPolarHBondContact O-CG 3.22Å; W535-M539 PolarHBondContact O-N 3.31Å
536K60.7Low56.7Low105 Ų10551.6 Ų51.646%0.45727%0.27SS..Hα-helixtrans-64.5-42.5176-176.6-178.1176.9-172.40111.6L381 L532 H533 E534 M539 L540L381-K536 HydrophobicContact CD2-CD 3.93Å; L532-K536 VanDerWaalsContact O-CB 3.24Å; L532-K536 WeakPolarHBondContact O-CB 3.32Å; L532-K536 PolarHBondContact O-N 2.92Å; H533-K536 PolarHBondContact O-N 3.41Å; E534-K536 VanDerWaalsContact C-N 3.31Å; E534-K536 PolarHBondContact O-N 3.39Å; K536-M539 PolarHBondContact O-N 2.85Å; K536-L540 HydrophobicContact CG-CD1 4.26Å; K536-L540 WeakPolarHBondContact O-CG 3.35Å; K536-L540 PolarHBondContact O-N 3.04Å
537A58.9Low55.6Low49 Ų4952.7 Ų52.741%0.40528%0.281SS..Hα-helixtrans-62.9-48.9175.600000110.5H533 E534 M539 L540 S541H533-A537 WeakPolarHBondContact O-CB 3.33Å; H533-A537 PolarHBondContact O-N 3.36Å; E534-A537 PolarHBondContact O-N 3.2Å; A537-M539 VanDerWaalsContact C-N 3.3Å; A537-M539 PolarHBondContact O-N 2.66Å; A537-L540 CarbonylContact O-C 3.58Å; A537-L540 WeakPolarHBondContact O-CA 3.48Å; A537-L540 WeakPolarHBondContact O-CB 3.35Å; A537-L540 PolarHBondContact O-N 3.02Å; A537-S541 PolarHBondContact O-N 3.28Å; A537-S541 PolarHBondContact O-OG 2.98Å; A537-S541 VanDerWaalsContact O-OG 3.11Å
538G49.3Very low54.8Low41 Ų4157.3 Ų57.342%0.42330%0.298SS..Hα-helixtrans-61.2-34.5175.600000113.2E534 W535 A542E534-G538 PolarHBondContact O-N 2.89Å; W535-G538 PolarHBondContact O-N 3.02Å; G538-A542 WeakPolarHBondContact O-CB 3.27Å; G538-A542 PolarHBondContact O-N 3.18Å
539M49.5Very low53.8Low41 Ų4159.2 Ų59.220%0.20231%0.308CS..Hα-helixtrans-68.5-38.7170.8-81.6-150.581.900113.1W535 K536 A537 R543W535-M539 HydrophobicContact CD2-CG 4.2Å; W535-M539 HydrophobicContact CD2-SD 4.36Å; W535-M539 HydrophobicContact CE3-SD 4.35Å; W535-M539 HydrophobicContact CH2-CG 4.15Å; W535-M539 HydrophobicContact CH2-SD 3.08Å; W535-M539 WeakPolarHBondContact CH2-SD 3.33Å; W535-M539 HydrophobicContact CZ2-CE 4.5Å; W535-M539 HydrophobicContact CZ2-CG 3.84Å; W535-M539 HydrophobicContact CZ2-SD 3.1Å; W535-M539 WeakPolarHBondContact CZ2-SD 3.33Å; W535-M539 HydrophobicContact CZ3-CG 4.48Å; W535-M539 HydrophobicContact CZ3-SD 3.76Å; W535-M539 WeakPolarHBondContact O-CB 3.48Å; W535-M539 WeakPolarHBondContact O-CG 3.22Å; W535-M539 PolarHBondContact O-N 3.31Å; K536-M539 PolarHBondContact O-N 2.85Å; A537-M539 VanDerWaalsContact C-N 3.3Å; A537-M539 PolarHBondContact O-N 2.66Å; M539-R543 WeakPolarHBondContact O-CB 3.32Å; M539-R543 WeakPolarHBondContact O-CG 3.41Å; M539-R543 PolarHBondContact O-N 3.38Å
540L50.7Low52.6Low83 Ų8364.4 Ų64.444%0.43533%0.331SS..Hα-helixtrans-67-47.9175.8-76.1163.6000110.4K536 A537 A542 R543 Q544K536-L540 HydrophobicContact CG-CD1 4.26Å; K536-L540 WeakPolarHBondContact O-CG 3.35Å; K536-L540 PolarHBondContact O-N 3.04Å; A537-L540 CarbonylContact O-C 3.58Å; A537-L540 WeakPolarHBondContact O-CA 3.48Å; A537-L540 WeakPolarHBondContact O-CB 3.35Å; A537-L540 PolarHBondContact O-N 3.02Å; L540-A542 VanDerWaalsContact C-N 3.32Å; L540-A542 PolarHBondContact O-N 3.42Å; L540-R543 CarbonylContact O-C 3.55Å; L540-R543 WeakPolarHBondContact O-CB 3.48Å; L540-R543 PolarHBondContact O-N 3.04Å; L540-R543 VanDerWaalsContact O-N 3.11Å; L540-Q544 WeakPolarHBondContact O-CG 3.49Å; L540-Q544 PolarHBondContact O-N 3.26Å
541S44.1Very low51.8Low40 Ų4068.2 Ų68.228%0.2834%0.343SS..Hα-helixtrans-59.6-41.6173.4-570000111.4A537 Q544 A545A537-S541 PolarHBondContact O-N 3.28Å; A537-S541 PolarHBondContact O-OG 2.98Å; A537-S541 VanDerWaalsContact O-OG 3.11Å; S541-Q544 PolarHBondContact O-N 3.07Å; S541-A545 VanDerWaalsContact O-CB 3.23Å; S541-A545 WeakPolarHBondContact O-CB 3.49Å; S541-A545 PolarHBondContact O-N 2.87Å
542A40.8Very low51Low18 Ų1868.2 Ų68.215%0.14934%0.343CS..Hα-helixtrans-66.8-36.1174.600000112.4G538 L540 I546G538-A542 WeakPolarHBondContact O-CB 3.27Å; G538-A542 PolarHBondContact O-N 3.18Å; L540-A542 VanDerWaalsContact C-N 3.32Å; L540-A542 PolarHBondContact O-N 3.42Å; A542-I546 WeakPolarHBondContact O-CB 3.2Å; A542-I546 WeakPolarHBondContact O-CD1 3.23Å; A542-I546 WeakPolarHBondContact O-CG1 3.45Å; A542-I546 PolarHBondContact O-N 2.92Å
543R45.5Very low50.1Low120 Ų12074.7 Ų74.745%0.45337%0.367SS..Hα-helixtrans-68.2-41.1173.7-83.9-176.7-178.3168.48.7111.8M333 M539 L540 I546 A547M333-R543 VanDerWaalsContact CE-NH2 3.25Å; M333-R543 VanDerWaalsContact SD-CZ 3.58Å; M333-R543 PolarHBondContact SD-NH2 3.4Å; M539-R543 WeakPolarHBondContact O-CB 3.32Å; M539-R543 WeakPolarHBondContact O-CG 3.41Å; M539-R543 PolarHBondContact O-N 3.38Å; L540-R543 CarbonylContact O-C 3.55Å; L540-R543 WeakPolarHBondContact O-CB 3.48Å; L540-R543 PolarHBondContact O-N 3.04Å; L540-R543 VanDerWaalsContact O-N 3.11Å; R543-I546 PolarHBondContact O-N 2.96Å; R543-A547 VanDerWaalsContact O-CB 3.28Å; R543-A547 WeakPolarHBondContact O-CB 3.34Å; R543-A547 PolarHBondContact O-N 3.46Å
544Q46.7Very low49.1Very low104 Ų10475.8 Ų75.849%0.48638%0.38SS..Hα-helixtrans-64-44.7174.6-73.9171.1-3900110.3L540 S541 I546 A547 W548 W641L540-Q544 WeakPolarHBondContact O-CG 3.49Å; L540-Q544 PolarHBondContact O-N 3.26Å; S541-Q544 PolarHBondContact O-N 3.07Å; Q544-I546 PolarHBondContact O-N 2.84Å; Q544-A547 PolarHBondContact O-N 2.79Å; Q544-W548 VanDerWaalsContact O-CB 3.26Å; Q544-W548 WeakPolarHBondContact O-CB 3.25Å; Q544-W548 PolarHBondContact O-N 3.38Å; Q544-W641 HydrophobicContact CB-CH2 4.28Å; Q544-W641 HydrophobicContact CB-CZ2 4.41Å
545A42.3Very low48.2Very low10 Ų1076.7 Ų76.78%0.08338%0.383CS..Hα-helixtrans-61.7-42.3173.400000111.9S541 W548 I549 Y638S541-A545 VanDerWaalsContact O-CB 3.23Å; S541-A545 WeakPolarHBondContact O-CB 3.49Å; S541-A545 PolarHBondContact O-N 2.87Å; A545-W548 PolarHBondContact O-N 3.12Å; A545-I549 WeakPolarHBondContact O-CB 3.34Å; A545-I549 WeakPolarHBondContact O-CD1 3.02Å; A545-I549 WeakPolarHBondContact O-CG1 3.46Å; A545-I549 PolarHBondContact O-N 3.23Å; A545-Y638 HydrophobicContact CB-CE1 4.09Å
546I43.5Very low47.1Very low72 Ų7277.8 Ų77.837%0.36940%0.403SS..Hα-helixtrans-64.7-46.4174.9-72.9163000110.8A542 R543 Q544 W548 I549 E550A542-I546 WeakPolarHBondContact O-CB 3.2Å; A542-I546 WeakPolarHBondContact O-CD1 3.23Å; A542-I546 WeakPolarHBondContact O-CG1 3.45Å; A542-I546 PolarHBondContact O-N 2.92Å; R543-I546 PolarHBondContact O-N 2.96Å; Q544-I546 PolarHBondContact O-N 2.84Å; I546-W548 VanDerWaalsContact C-N 3.27Å; I546-W548 PolarHBondContact O-N 2.85Å; I546-I549 CarbonylContact O-C 3.54Å; I546-I549 PolarHBondContact O-N 3.05Å; I546-E550 HydrophobicContact CG2-CG 4.25Å; I546-E550 WeakPolarHBondContact O-CB 3.38Å; I546-E550 VanDerWaalsContact O-CG 3.31Å; I546-E550 WeakPolarHBondContact O-CG 3.24Å; I546-E550 PolarHBondContact O-N 3.43Å
547A47.9Very low46Very low54 Ų5478.5 Ų78.545%0.44641%0.411SS..Hα-helixtrans-63.3-35.9178.200000111.5R543 Q544 Y551R543-A547 VanDerWaalsContact O-CB 3.28Å; R543-A547 WeakPolarHBondContact O-CB 3.34Å; R543-A547 PolarHBondContact O-N 3.46Å; Q544-A547 PolarHBondContact O-N 2.79Å; A547-Y551 WeakPolarHBondContact O-CB 3.49Å; A547-Y551 PolarHBondContact O-N 3.45Å
548W50.2Low45.3Very low100 Ų10083 Ų8338%0.37942%0.418SS..Hα-helixtrans-69.7-43.4172.8-178.177.4000111.6Q544 A545 I546 E550 Y551 E552Q544-W548 VanDerWaalsContact O-CB 3.26Å; Q544-W548 WeakPolarHBondContact O-CB 3.25Å; Q544-W548 PolarHBondContact O-N 3.38Å; A545-W548 PolarHBondContact O-N 3.12Å; I546-W548 VanDerWaalsContact C-N 3.27Å; I546-W548 PolarHBondContact O-N 2.85Å; W548-E550 VanDerWaalsContact C-N 3.33Å; W548-E550 PolarHBondContact O-N 3.34Å; W548-Y551 CarbonylContact O-C 3.55Å; W548-Y551 WeakPolarHBondContact O-CB 3.31Å; W548-Y551 PolarHBondContact O-N 3.45Å; W548-Y551 VanDerWaalsContact O-N 3.16Å; W548-E552 HydrophobicContact CD2-CG 3.81Å; W548-E552 VanDerWaalsContact CE2-CG 3.41Å; W548-E552 HydrophobicContact CE3-CG 4.17Å; W548-E552 HydrophobicContact CG-CG 4.42Å; W548-E552 HydrophobicContact CH2-CG 3.85Å; W548-E552 HydrophobicContact CZ2-CG 3.44Å; W548-E552 VanDerWaalsContact CZ2-CG 3.44Å; W548-E552 HydrophobicContact CZ3-CG 4.18Å; W548-E552 PolarHBondContact NE1-OE1 3.41Å; W548-E552 WeakPolarHBondContact O-CB 3.3Å; W548-E552 VanDerWaalsContact O-CG 3.31Å; W548-E552 WeakPolarHBondContact O-CG 3.43Å; W548-E552 PolarHBondContact O-N 3.25Å
549I44.2Very low44.9Very low39 Ų3982.9 Ų82.920%0.241%0.411CS..Hα-helixtrans-61.3-42.8173.6-71.6163000110.4A545 I546 Y551 E552 W553 M561A545-I549 WeakPolarHBondContact O-CB 3.34Å; A545-I549 WeakPolarHBondContact O-CD1 3.02Å; A545-I549 WeakPolarHBondContact O-CG1 3.46Å; A545-I549 PolarHBondContact O-N 3.23Å; I546-I549 CarbonylContact O-C 3.54Å; I546-I549 PolarHBondContact O-N 3.05Å; I549-Y551 VanDerWaalsContact C-N 3.34Å; I549-E552 PolarHBondContact O-N 3.05Å; I549-W553 WeakPolarHBondContact O-CB 3.4Å; I549-W553 PolarHBondContact O-N 2.91Å; I549-M561 HydrophobicContact CD1-CE 4.42Å; I549-M561 HydrophobicContact CD1-SD 3.81Å
550E44.7Very low44.5Very low122 Ų12284 Ų8457%0.5742%0.417SS*.Hα-helixtrans-64.1-39.5174.3-75.1175.3171.900111.1I546 W548 W553 V554I546-E550 HydrophobicContact CG2-CG 4.25Å; I546-E550 WeakPolarHBondContact O-CB 3.38Å; I546-E550 VanDerWaalsContact O-CG 3.31Å; I546-E550 WeakPolarHBondContact O-CG 3.24Å; I546-E550 PolarHBondContact O-N 3.43Å; W548-E550 VanDerWaalsContact C-N 3.33Å; W548-E550 PolarHBondContact O-N 3.34Å; E550-W553 PolarHBondContact O-N 3.01Å; E550-V554 WeakPolarHBondContact O-CB 3.29Å; E550-V554 VanDerWaalsContact O-CG2 3.22Å; E550-V554 WeakPolarHBondContact O-CG2 3.35Å; E550-V554 PolarHBondContact O-N 2.85Å
551Y50.9Low44.1Very low130 Ų13083.6 Ų83.651%0.5141%0.414SS..Hα-helixtrans-63.2-51174.1177.2-93.9000111.6A547 W548 I549 W553 V554 H555A547-Y551 WeakPolarHBondContact O-CB 3.49Å; A547-Y551 PolarHBondContact O-N 3.45Å; W548-Y551 CarbonylContact O-C 3.55Å; W548-Y551 WeakPolarHBondContact O-CB 3.31Å; W548-Y551 PolarHBondContact O-N 3.45Å; W548-Y551 VanDerWaalsContact O-N 3.16Å; I549-Y551 VanDerWaalsContact C-N 3.34Å; Y551-W553 VanDerWaalsContact C-N 3.31Å; Y551-W553 PolarHBondContact O-N 2.89Å; Y551-V554 PolarHBondContact O-N 3.34Å; Y551-H555 AromaticContact CD2-CE1 3.63Å; Y551-H555 AromaticContact CD2-ND1 3.51Å; Y551-H555 AromaticContact CE2-CE1 3.58Å; Y551-H555 AromaticContact CE2-ND1 3.59Å; Y551-H555 AromaticContact CG-ND1 3.93Å; Y551-H555 WeakPolarHBondContact O-CB 3.13Å; Y551-H555 PolarHBondContact O-N 3.06Å; Y551-H555 PolarHBondContact O-ND1 3.48Å
552E47.5Very low44Very low54 Ų5483.4 Ų83.425%0.25241%0.411SS..Hα-helixtrans-63.1-36.4176.5-70.3-67.7145.900112W548 I549 H555 S556 N557W548-E552 HydrophobicContact CD2-CG 3.81Å; W548-E552 VanDerWaalsContact CE2-CG 3.41Å; W548-E552 HydrophobicContact CE3-CG 4.17Å; W548-E552 HydrophobicContact CG-CG 4.42Å; W548-E552 HydrophobicContact CH2-CG 3.85Å; W548-E552 HydrophobicContact CZ2-CG 3.44Å; W548-E552 VanDerWaalsContact CZ2-CG 3.44Å; W548-E552 HydrophobicContact CZ3-CG 4.18Å; W548-E552 PolarHBondContact NE1-OE1 3.41Å; W548-E552 WeakPolarHBondContact O-CB 3.3Å; W548-E552 VanDerWaalsContact O-CG 3.31Å; W548-E552 WeakPolarHBondContact O-CG 3.43Å; W548-E552 PolarHBondContact O-N 3.25Å; I549-E552 PolarHBondContact O-N 3.05Å; E552-H555 PolarHBondContact O-N 3.29Å; E552-S556 PolarHBondContact O-N 3.06Å; E552-N557 PolarHBondContact O-N 3.31Å
553W43.9Very low44Very low139 Ų13989.5 Ų89.553%0.52743%0.43SS..Hα-helixtrans-63.1-41.5174.8-176.1-82.4000111.6I549 E550 Y551 C559I549-W553 WeakPolarHBondContact O-CB 3.4Å; I549-W553 PolarHBondContact O-N 2.91Å; E550-W553 PolarHBondContact O-N 3.01Å; Y551-W553 VanDerWaalsContact C-N 3.31Å; Y551-W553 PolarHBondContact O-N 2.89Å; W553-C559 VanDerWaalsContact CZ3-O 3.3Å; W553-C559 WeakPolarHBondContact CZ3-O 3.25Å
554V46.1Very low43.7Very low106 Ų10684.8 Ų84.864%0.64241%0.414SS*.Hα-helixtrans-77.3-30.3177.4173.20000112.1E550 Y551E550-V554 WeakPolarHBondContact O-CB 3.29Å; E550-V554 VanDerWaalsContact O-CG2 3.22Å; E550-V554 WeakPolarHBondContact O-CG2 3.35Å; E550-V554 PolarHBondContact O-N 2.85Å; Y551-V554 PolarHBondContact O-N 3.34Å
555H45.1Very low43.2Very low108 Ų10883.2 Ų83.250%0.542%0.415SS..Hα-helixtrans-108.614.2-169.8-62.385.1000115.7Y551 E552Y551-H555 AromaticContact CD2-CE1 3.63Å; Y551-H555 AromaticContact CD2-ND1 3.51Å; Y551-H555 AromaticContact CE2-CE1 3.58Å; Y551-H555 AromaticContact CE2-ND1 3.59Å; Y551-H555 AromaticContact CG-ND1 3.93Å; Y551-H555 WeakPolarHBondContact O-CB 3.13Å; Y551-H555 PolarHBondContact O-N 3.06Å; Y551-H555 PolarHBondContact O-ND1 3.48Å; E552-H555 PolarHBondContact O-N 3.29Å
556S36.6Very low42.8Very low99 Ų9989 Ų8969%0.69244%0.444SS*.THydrogen-bonded Turntrans98.951.7163.4-39.60000118.2E552E552-S556 PolarHBondContact O-N 3.06Å
557N38Very low42.4Very low119 Ų11990 Ų9064%0.63646%0.458SS*.  trans-147.3141149.9-88.4-44.3000113.7E552E552-N557 PolarHBondContact O-N 3.31Å
558R43.7Very low41.5Very low143 Ų14393 Ų9354%0.5447%0.474SS..  trans-88.2101.9-160.9-65.6157.6165.3177.47.2111.8R598 H599 Q600R558-R598 PolarHBondContact NH1-O 3.47Å; R558-H599 HydrophobicContact CB-CB 4.01Å; R558-H599 VanDerWaalsContact CD-CE1 3.44Å; R558-H599 WeakPolarHBondContact CD-CE1 3.22Å; R558-H599 WeakPolarHBondContact CD-ND1 3.23Å; R558-H599 PolarHBondContact NE-CE1 2.91Å; R558-H599 PolarHBondContact NE-ND1 3.02Å; R558-Q600 VanDerWaalsContact O-O 3.08Å
559C41.7Very low40.5Very low40 Ų4093.9 Ų93.927%0.2750%0.496SS..  trans-134.1133.2-179.9-163.80000113.2W553W553-C559 VanDerWaalsContact CZ3-O 3.3Å; W553-C559 WeakPolarHBondContact CZ3-O 3.25Å
560L41Very low39.6Very low63 Ų63100 Ų10033%0.3352%0.523SS..  trans-118.4104174.7-158.6126.3000108.9V562 L590L560-V562 HydrophobicContact CD2-CG2 3.8Å; L560-V562 PolarHBondContact O-N 3.35Å; L560-L590 HydrophobicContact CD1-CD1 4.33Å; L560-L590 HydrophobicContact CD2-CD1 3.74Å
561M42.5Very low38.8Very low76 Ų76102.9 Ų102.937%0.37453%0.534SS..  trans-84.2112-177.8-174-177.56900110.5I549 L604I549-M561 HydrophobicContact CD1-CE 4.42Å; I549-M561 HydrophobicContact CD1-SD 3.81Å; M561-L604 HydrophobicContact CG-CD1 3.97Å; M561-L604 HydrophobicContact SD-CD1 4.04Å
562V42.1Very low37.7Very low35 Ų35108.1 Ų108.121%0.21255%0.553CS.*EExtended strand (participates in β ladder)trans-105.4125.5170.5-167.10000109.1L560 L583L560-V562 HydrophobicContact CD2-CG2 3.8Å; L560-V562 PolarHBondContact O-N 3.35Å; V562-L583 HydrophobicContact CB-CD2 4.27Å; V562-L583 HydrophobicContact CG1-CD2 3.26Å
563R40.9Very low36.7Very low146 Ų146114.9 Ų114.955%0.55159%0.585SS**EExtended strand (participates in β ladder)trans-110.6111.7-175.5-157.9179.8-171.3162.34.6108.9S565R563-S565 PolarHBondContact O-N 3.22Å
564T39Very low35.8Very low21 Ų21111.2 Ų111.213%0.12959%0.59CS.*  trans-81.392168.355.40000108.1L583T564-L583 HydrophobicContact CG2-CD1 3.29Å; T564-L583 HydrophobicContact CG2-CD2 4.14Å; T564-L583 HydrophobicContact CG2-CG 4.29Å
565S35.8Very low35Very low72 Ų72115.3 Ų115.350%0.50360%0.602SS.*  trans-93.4121.2164.859.90000108.9R563 S567R563-S565 PolarHBondContact O-N 3.22Å; S565-S567 PolarHBondContact O-N 3.05Å; S565-S567 PolarHBondContact O-OG 3.35Å
566D34.4Very low34.5Very low131 Ų131119.1 Ų119.170%0.70163%0.625SS**SBendtrans-50.395.2171.4-66.3-28.6000111.1
567S35.1Very low34.6Very low93 Ų93118.3 Ų118.365%0.6562%0.624SS**  trans-159.94.1167.249.50000114.1S565 S569S565-S567 PolarHBondContact O-N 3.05Å; S565-S567 PolarHBondContact O-OG 3.35Å; S567-S569 PolarHBondContact O-N 2.87Å
568C28.7Very low35.3Very low117 Ų117115.8 Ų115.879%0.79161%0.611SS**  trans-95.765.4169.5-70.90000110.9
569S28.3Very low35.6Very low118 Ų118112.8 Ų112.883%0.82561%0.609SS**  trans-128.212.9166.280.40000113.9S567S567-S569 PolarHBondContact O-N 2.87Å
570E26.8Very low35.9Very low168 Ų168111.7 Ų111.779%0.78560%0.6SS**SBendtrans-95.7111.2162.7-71.9-167.4162.800109.1
571K26.5Very low36.3Very low182 Ų182111.1 Ų111.179%0.79160%0.597SS**  trans86.3114.8176.1-49.4158.2-172.8179.80110.9
572W27.7Very low36.7Very low240 Ų240113.9 Ų113.991%0.90961%0.609SS**  -144.4148.355.5-81.869000112.8
573E26.1Very low37.2Very low197 Ų197113.4 Ų113.492%0.92161%0.606SS**SBendtrans-71.7121.3163.5-68.7176.8152.200108.7
574G26.7Very low37.7Very low62 Ų62106.8 Ų106.864%0.63958%0.581SS**SBendtrans98125.5173.900000113.5
575E29.6Very low38.5Very low192 Ų192113.3 Ų113.390%0.89760%0.603SS**SBendtrans78122.5179.3-59.3-174.9166.100116.6A577E575-A577 VanDerWaalsContact C-N 3.27Å; E575-A577 PolarHBondContact O-N 3.03Å
576L34.6Very low39.3Very low187 Ų187114.7 Ų114.798%0.97960%0.603SS**  trans-60.682.8169.3-76.6137.4000109.4D578L576-D578 PolarHBondContact O-N 2.87Å; L576-D578 VanDerWaalsContact O-N 3.15Å
577A38.6Very low40.3Very low82 Ų82109.9 Ų109.968%0.67858%0.575SS**  trans-76.1100.2170.600000108.8E575 V579E575-A577 VanDerWaalsContact C-N 3.27Å; E575-A577 PolarHBondContact O-N 3.03Å; A577-V579 PolarHBondContact O-N 3.3Å
578D52.5Low41.3Very low67 Ų67108.7 Ų108.736%0.35856%0.562SS.*  trans-66.4111.4172.2-168.7-14.8000109.1L576 T580 L581 E582L576-D578 PolarHBondContact O-N 2.87Å; L576-D578 VanDerWaalsContact O-N 3.15Å; D578-T580 PolarHBondContact O-N 3.07Å; D578-T580 WeakPolarHBondContact OD1-CB 3.49Å; D578-T580 PolarHBondContact OD1-N 3.44Å; D578-T580 PolarHBondContact OD1-OG1 3.41Å; D578-L581 HydrophobicContact CB-CB 4.16Å; D578-L581 VanDerWaalsContact O-CB 3.29Å; D578-L581 WeakPolarHBondContact O-CB 3.4Å; D578-L581 PolarHBondContact O-N 3.43Å; D578-E582 PolarHBondContact O-N 3.39Å
579V48.7Very low42.6Very low80 Ų80108.4 Ų108.449%0.48555%0.552SS.*Hα-helixtrans-53.1-27.7177179.70000111.3A577 L583A577-V579 PolarHBondContact O-N 3.3Å; V579-L583 WeakPolarHBondContact O-CD1 3.43Å; V579-L583 WeakPolarHBondContact O-CG 3.47Å; V579-L583 PolarHBondContact O-N 3.24Å
580T49Very low43.7Very low16 Ų16106 Ų10610%0.09853%0.53CS..Hα-helixtrans-63.8-40.5174.5-42.70000112D578 L583 V584 I617 Q620D578-T580 PolarHBondContact O-N 3.07Å; D578-T580 WeakPolarHBondContact OD1-CB 3.49Å; D578-T580 PolarHBondContact OD1-N 3.44Å; D578-T580 PolarHBondContact OD1-OG1 3.41Å; T580-L583 PolarHBondContact O-N 3.49Å; T580-V584 WeakPolarHBondContact O-CG2 3.49Å; T580-V584 PolarHBondContact O-N 3.43Å; T580-I617 HydrophobicContact CG2-CB 4.12Å; T580-I617 HydrophobicContact CG2-CG1 3.7Å; T580-Q620 HydrophobicContact CG2-CB 3.93Å; T580-Q620 HydrophobicContact CG2-CG 4.13Å
581L49.7Very low45Very low51 Ų51101.9 Ų101.927%0.26751%0.512SS..Hα-helixtrans-70.6-33.5-178.9-165.874.4000112D578 R585D578-L581 HydrophobicContact CB-CB 4.16Å; D578-L581 VanDerWaalsContact O-CB 3.29Å; D578-L581 WeakPolarHBondContact O-CB 3.4Å; D578-L581 PolarHBondContact O-N 3.43Å; L581-R585 WeakPolarHBondContact O-CB 3.42Å; L581-R585 VanDerWaalsContact O-CG 3.23Å; L581-R585 WeakPolarHBondContact O-CG 3.39Å; L581-R585 PolarHBondContact O-N 3.24Å
582E51Low46.5Very low134 Ų134100.1 Ų100.163%0.62650%0.504SS*.Hα-helixtrans-65.6-40.3174.7-78.8-159.2152.700112.3D578 R585 M586D578-E582 PolarHBondContact O-N 3.39Å; E582-R585 PolarHBondContact O-N 2.86Å; E582-M586 WeakPolarHBondContact O-CB 3.35Å; E582-M586 PolarHBondContact O-N 3.38Å
583L52.6Low47.3Very low26 Ų2695.5 Ų95.514%0.13649%0.491CS..Hα-helixtrans-65.3-43.9178.9-70.1159.9000111.9V562 T564 V579 T580 M586 Y587V562-L583 HydrophobicContact CB-CD2 4.27Å; V562-L583 HydrophobicContact CG1-CD2 3.26Å; T564-L583 HydrophobicContact CG2-CD1 3.29Å; T564-L583 HydrophobicContact CG2-CD2 4.14Å; T564-L583 HydrophobicContact CG2-CG 4.29Å; V579-L583 WeakPolarHBondContact O-CD1 3.43Å; V579-L583 WeakPolarHBondContact O-CG 3.47Å; V579-L583 PolarHBondContact O-N 3.24Å; T580-L583 PolarHBondContact O-N 3.49Å; L583-M586 WeakPolarHBondContact O-CB 3.42Å; L583-M586 PolarHBondContact O-N 3.16Å; L583-Y587 PolarHBondContact O-N 3.45Å
584V51.3Low48.3Very low6 Ų691.9 Ų91.94%0.03648%0.484CS..Hα-helixtrans-68.1-39.4179.1178.80000111.3T580 Y587 D588 Q620 D624 V626T580-V584 WeakPolarHBondContact O-CG2 3.49Å; T580-V584 PolarHBondContact O-N 3.43Å; V584-Y587 WeakPolarHBondContact O-CB 3.49Å; V584-Y587 PolarHBondContact O-N 2.85Å; V584-D588 PolarHBondContact O-N 3.33Å; V584-Q620 HydrophobicContact CG2-CG 4.33Å; V584-D624 HydrophobicContact CG1-CB 3.33Å; V584-D624 WeakPolarHBondContact CG1-OD2 3.4Å; V584-V626 HydrophobicContact CG1-CG2 4.02Å
585R54Low49.4Very low158 Ų15893.4 Ų93.460%0.59648%0.483SS*.Hα-helixtrans-66.5-36.5172.4-73.5175.6176.9-172.70.6113.1L581 E582 Y587 L589L581-R585 WeakPolarHBondContact O-CB 3.42Å; L581-R585 VanDerWaalsContact O-CG 3.23Å; L581-R585 WeakPolarHBondContact O-CG 3.39Å; L581-R585 PolarHBondContact O-N 3.24Å; E582-R585 PolarHBondContact O-N 2.86Å; R585-Y587 VanDerWaalsContact C-N 3.31Å; R585-L589 WeakPolarHBondContact O-CB 3.46Å; R585-L589 PolarHBondContact O-N 3.34Å; R585-L589 VanDerWaalsContact O-N 3.11Å
586M53.2Low50.5Low101 Ų10189 Ų8950%0.49846%0.459SS..Hα-helixtrans-62.8-40.3173.5-111.1-173.464.300111.6E582 L583 L589 L590E582-M586 WeakPolarHBondContact O-CB 3.35Å; E582-M586 PolarHBondContact O-N 3.38Å; L583-M586 WeakPolarHBondContact O-CB 3.42Å; L583-M586 PolarHBondContact O-N 3.16Å; M586-L589 WeakPolarHBondContact O-CB 3.29Å; M586-L589 PolarHBondContact O-N 3.38Å; M586-L590 HydrophobicContact CE-CD1 4.49Å; M586-L590 VanDerWaalsContact O-CG 3.32Å; M586-L590 WeakPolarHBondContact O-CG 3.45Å; M586-L590 PolarHBondContact O-N 3.18Å
587Y55.5Low51Low30 Ų3085.2 Ų85.212%0.11845%0.445CS..Hα-helixtrans-63.5-48.8176.8172.5-93.7000111.7L583 V584 R585 L589 L590 I591 V601 V626 I629L583-Y587 PolarHBondContact O-N 3.45Å; V584-Y587 WeakPolarHBondContact O-CB 3.49Å; V584-Y587 PolarHBondContact O-N 2.85Å; R585-Y587 VanDerWaalsContact C-N 3.31Å; Y587-L589 VanDerWaalsContact C-N 3.26Å; Y587-L589 PolarHBondContact O-N 3.08Å; Y587-L590 PolarHBondContact O-N 3.35Å; Y587-I591 HydrophobicContact CD1-CD1 3.51Å; Y587-I591 HydrophobicContact CD1-CG1 4.4Å; Y587-I591 HydrophobicContact CD2-CD1 4.44Å; Y587-I591 HydrophobicContact CE1-CD1 2.95Å; Y587-I591 HydrophobicContact CE1-CG1 4.01Å; Y587-I591 HydrophobicContact CE2-CD1 4.01Å; Y587-I591 HydrophobicContact CE2-CG1 4.25Å; Y587-I591 HydrophobicContact CG-CD1 4.22Å; Y587-I591 WeakPolarHBondContact O-CG1 3.39Å; Y587-I591 PolarHBondContact O-N 3.24Å; Y587-V601 HydrophobicContact CD2-CB 4.35Å; Y587-V601 HydrophobicContact CD2-CG1 4.24Å; Y587-V601 HydrophobicContact CD2-CG2 4.16Å; Y587-V601 HydrophobicContact CE2-CB 3.79Å; Y587-V601 HydrophobicContact CE2-CG1 4.18Å; Y587-V601 HydrophobicContact CE2-CG2 3.53Å; Y587-V626 HydrophobicContact CD1-CB 4.07Å; Y587-V626 HydrophobicContact CD1-CG1 3.61Å; Y587-V626 HydrophobicContact CD1-CG2 3.38Å; Y587-V626 HydrophobicContact CE1-CB 3.63Å; Y587-V626 HydrophobicContact CE1-CG1 2.97Å; Y587-V626 HydrophobicContact CE1-CG2 3.4Å; Y587-V626 HydrophobicContact CE2-CG1 4.12Å; Y587-V626 HydrophobicContact CG-CG1 4.39Å; Y587-V626 HydrophobicContact CG-CG2 4.5Å; Y587-I629 HydrophobicContact CE2-CG1 4.48Å
588D56.5Low51.5Low69 Ų6991.4 Ų91.437%0.36945%0.451SS..Hα-helixtrans-57.2-39.1175.4-177.145.6000112.2V584 L590 K592V584-D588 PolarHBondContact O-N 3.33Å; D588-L590 PolarHBondContact O-N 2.89Å; D588-K592 WeakPolarHBondContact O-CB 3.39Å; D588-K592 WeakPolarHBondContact O-CD 3.41Å; D588-K592 VanDerWaalsContact O-CG 3.26Å; D588-K592 WeakPolarHBondContact O-CG 3.46Å; D588-K592 PolarHBondContact O-N 2.95Å; D588-K592 WeakPolarHBondContact OD1-CE 3.32Å; D588-K592 IonicContact OD1-NZ 2.59Å; D588-K592 PolarHBondContact OD1-NZ 2.92Å; D588-K592 IonicContact OD2-NZ 2.91Å; D588-K592 PolarHBondContact OD2-NZ 3.18Å
589L55.8Low51.4Low110 Ų11091.1 Ų91.158%0.57645%0.448SS*.Hα-helixtrans-65.5-33.3174.1-97.9153.9000114.3R585 M586 Y587R585-L589 WeakPolarHBondContact O-CB 3.46Å; R585-L589 PolarHBondContact O-N 3.34Å; R585-L589 VanDerWaalsContact O-N 3.11Å; M586-L589 WeakPolarHBondContact O-CB 3.29Å; M586-L589 PolarHBondContact O-N 3.38Å; Y587-L589 VanDerWaalsContact C-N 3.26Å; Y587-L589 PolarHBondContact O-N 3.08Å
590L51.3Low51.6Low69 Ų6993.9 Ų93.936%0.36146%0.455SS..Hα-helixtrans-78.4-37-179.2-76.9165.4000112.1L560 M586 Y587 D588L560-L590 HydrophobicContact CD1-CD1 4.33Å; L560-L590 HydrophobicContact CD2-CD1 3.74Å; M586-L590 HydrophobicContact CE-CD1 4.49Å; M586-L590 VanDerWaalsContact O-CG 3.32Å; M586-L590 WeakPolarHBondContact O-CG 3.45Å; M586-L590 PolarHBondContact O-N 3.18Å; Y587-L590 PolarHBondContact O-N 3.35Å; D588-L590 PolarHBondContact O-N 2.89Å
591I54.8Low51.7Low80 Ų8093.9 Ų93.941%0.4146%0.455SS..Hα-helixtrans-69.8-35.5175.4-56.4159.8000111.5Y587 K593Y587-I591 HydrophobicContact CD1-CD1 3.51Å; Y587-I591 HydrophobicContact CD1-CG1 4.4Å; Y587-I591 HydrophobicContact CD2-CD1 4.44Å; Y587-I591 HydrophobicContact CE1-CD1 2.95Å; Y587-I591 HydrophobicContact CE1-CG1 4.01Å; Y587-I591 HydrophobicContact CE2-CD1 4.01Å; Y587-I591 HydrophobicContact CE2-CG1 4.25Å; Y587-I591 HydrophobicContact CG-CD1 4.22Å; Y587-I591 WeakPolarHBondContact O-CG1 3.39Å; Y587-I591 PolarHBondContact O-N 3.24Å; I591-K593 PolarHBondContact O-N 2.91Å
592K57.2Low52.2Low146 Ų14693.4 Ų93.464%0.63545%0.453SS*.THydrogen-bonded Turntrans-72.5-6.3-178.6-75.8172.6176.8164.30114.3D588D588-K592 WeakPolarHBondContact O-CB 3.39Å; D588-K592 WeakPolarHBondContact O-CD 3.41Å; D588-K592 VanDerWaalsContact O-CG 3.26Å; D588-K592 WeakPolarHBondContact O-CG 3.46Å; D588-K592 PolarHBondContact O-N 2.95Å; D588-K592 WeakPolarHBondContact OD1-CE 3.32Å; D588-K592 IonicContact OD1-NZ 2.59Å; D588-K592 PolarHBondContact OD1-NZ 2.92Å; D588-K592 IonicContact OD2-NZ 2.91Å; D588-K592 PolarHBondContact OD2-NZ 3.18Å
593K45.8Very low52.8Low142 Ų14287.6 Ų87.662%0.61743%0.426SS*.SBendtrans-108128.8177.8-80.7-169.2174.6-178.60112.2I591I591-K593 PolarHBondContact O-N 2.91Å
594P46.2Very low53.3Low121 Ų12187 Ų8779%0.78642%0.422SS*.THydrogen-bonded Turntrans-56.5144.3167.3-16.528.3000110.3
595P49.3Very low53.7Low95 Ų9586.7 Ų86.762%0.61742%0.42SS*.THydrogen-bonded Turncis-10524.421.240.7-37.7000115.7P597P595-P597 WeakPolarHBondContact O-CD 3.26Å
596Y52.9Low54Low100 Ų10083.1 Ų83.139%0.39241%0.413SS..  trans-10488.4-162.6-54.7-71.5000115H599Y596-H599 AromaticContact CD1-NE2 3.96Å
597P45.5Very low54.4Low107 Ų10782.3 Ų82.370%0.69541%0.405SS*.  trans-94.6-0.1-164.7-1.225000114.5P595P595-P597 WeakPolarHBondContact O-CD 3.26Å
598R48.1Very low55Low211 Ų21183.8 Ų83.880%0.79642%0.42SS*.SBendtrans179.789.5-174.5-107.1165.9-166.6-167.43.4114.6R558R558-R598 PolarHBondContact NH1-O 3.47Å
599H51.8Low55.8Low62 Ų6283.5 Ų83.529%0.28742%0.422SS..  trans-135.9132-176.8-65.313.6000112.5R558 Y596R558-H599 HydrophobicContact CB-CB 4.01Å; R558-H599 VanDerWaalsContact CD-CE1 3.44Å; R558-H599 WeakPolarHBondContact CD-CE1 3.22Å; R558-H599 WeakPolarHBondContact CD-ND1 3.23Å; R558-H599 PolarHBondContact NE-CE1 2.91Å; R558-H599 PolarHBondContact NE-ND1 3.02Å; Y596-H599 AromaticContact CD1-NE2 3.96Å
600Q52Low56.7Low138 Ų13886.5 Ų86.565%0.64543%0.431SS*.  trans-63.1134.4162.2-92.2175.5-13.800109R558 D628R558-Q600 VanDerWaalsContact O-O 3.08Å; Q600-D628 HydrophobicContact CG-CB 3.88Å
601V52.2Low57.9Low15 Ų1584.2 Ų84.29%0.09142%0.421CS..EExtended strand (participates in β ladder)trans-120.7123.6-178.9169.60000110.4Y587 D628 I629 D630Y587-V601 HydrophobicContact CD2-CB 4.35Å; Y587-V601 HydrophobicContact CD2-CG1 4.24Å; Y587-V601 HydrophobicContact CD2-CG2 4.16Å; Y587-V601 HydrophobicContact CE2-CB 3.79Å; Y587-V601 HydrophobicContact CE2-CG1 4.18Å; Y587-V601 HydrophobicContact CE2-CG2 3.53Å; V601-D628 PolarHBondContact N-O 3.31Å; V601-I629 HydrophobicContact CB-CG1 4.18Å; V601-I629 HydrophobicContact CG1-CG1 4.26Å; V601-I629 CarbonylContact O-C 3.56Å; V601-I629 WeakPolarHBondContact O-CA 3.28Å; V601-D630 PolarHBondContact O-N 3.24Å
602I59.6Low58.8Low42 Ų4285.2 Ų85.222%0.21542%0.424CS..EExtended strand (participates in β ladder)trans-92.3116.3174-54.7176.8000108.6L604 D630 R632I602-L604 HydrophobicContact CG2-CD2 3.82Å; I602-L604 HydrophobicContact CG2-CG 4.35Å; I602-D630 CarbonylContact C-O 3.59Å; I602-D630 WeakPolarHBondContact CA-O 3.41Å; I602-D630 HydrophobicContact CG1-CB 4.12Å; I602-R632 HydrophobicContact CG2-CG 4.33Å
603L63.2Low59.3Low12 Ų1282.2 Ų82.26%0.06341%0.412CS..EExtended strand (participates in β ladder)trans-98.5111.4176.9-161.8149.8000109I617 I629 D630 V631 R632L603-I617 HydrophobicContact CD2-CG2 4.04Å; L603-I629 HydrophobicContact CD1-CD1 4.15Å; L603-D630 PolarHBondContact N-O 3.36Å; L603-V631 HydrophobicContact CB-CG2 4.35Å; L603-V631 HydrophobicContact CD2-CG1 4.27Å; L603-V631 CarbonylContact O-C 3.45Å; L603-V631 WeakPolarHBondContact O-CA 3.43Å; L603-R632 PolarHBondContact O-N 3.02Å
604L62.1Low60.5Low12 Ų1276.8 Ų76.86%0.06339%0.388CS..EExtended strand (participates in β ladder)trans-93.2121.5-179.5-63.4-176.5000110.1M561 I602 R632 V634 F637M561-L604 HydrophobicContact CG-CD1 3.97Å; M561-L604 HydrophobicContact SD-CD1 4.04Å; I602-L604 HydrophobicContact CG2-CD2 3.82Å; I602-L604 HydrophobicContact CG2-CG 4.35Å; L604-R632 WeakPolarHBondContact CA-O 3.46Å; L604-R632 HydrophobicContact CD2-CB 3.94Å; L604-V634 HydrophobicContact CB-CG2 3.81Å; L604-F637 HydrophobicContact CD1-CD1 4.22Å; L604-F637 HydrophobicContact CD1-CE1 4.33Å; L604-F637 HydrophobicContact CD2-CB 4.06Å; L604-F637 HydrophobicContact CD2-CD1 4.17Å; L604-F637 HydrophobicContact CD2-CD2 4.13Å; L604-F637 HydrophobicContact CD2-CG 3.85Å
605T61.2Low62Low0 Ų075.9 Ų75.90%037%0.372CS..EExtended strand (participates in β ladder)trans-123.3147.5-179.8-179.80000112.4Y607 F614 V631 R632 N633 V634T605-Y607 PolarHBondContact O-N 3.23Å; T605-Y607 WeakPolarHBondContact OG1-CD2 3.46Å; T605-Y607 PolarHBondContact OG1-N 3.15Å; T605-F614 HydrophobicContact CG2-CD2 3.48Å; T605-F614 VanDerWaalsContact CG2-CD2 3.48Å; T605-F614 HydrophobicContact CG2-CE2 3.68Å; T605-V631 HydrophobicContact CG2-CG1 3.9Å; T605-R632 PolarHBondContact N-O 3.21Å; T605-N633 CarbonylContact O-C 3.59Å; T605-N633 VanDerWaalsContact O-CA 3.31Å; T605-N633 WeakPolarHBondContact O-CA 3.35Å; T605-V634 WeakPolarHBondContact O-CG2 3.2Å; T605-V634 PolarHBondContact O-N 2.94Å
606D59Low63.2Low83 Ų8378.4 Ų78.444%0.44437%0.369SS..SBendtrans-75.9-16.2174.8-62.1-11000111.4N633 V634D606-N633 PolarHBondContact O-ND2 2.99Å; D606-V634 WeakPolarHBondContact OD1-CG2 3.39Å
607Y62Low63.9Low85 Ų8574 Ų7433%0.33335%0.352SS..SBendtrans-65.5132177.7-69.1-56.9000111.6T605 S611 E613 F614 I617 N633T605-Y607 PolarHBondContact O-N 3.23Å; T605-Y607 WeakPolarHBondContact OG1-CD2 3.46Å; T605-Y607 PolarHBondContact OG1-N 3.15Å; Y607-S611 WeakPolarHBondContact CB-OG 3.5Å; Y607-E613 HydrophobicContact CD1-CB 3.5Å; Y607-E613 HydrophobicContact CD1-CG 4.03Å; Y607-E613 HydrophobicContact CD2-CB 3.8Å; Y607-E613 HydrophobicContact CE1-CB 3.54Å; Y607-E613 HydrophobicContact CE1-CG 3.64Å; Y607-E613 HydrophobicContact CE2-CB 3.86Å; Y607-E613 HydrophobicContact CG-CB 3.66Å; Y607-F614 WeakPolarHBondContact O-CD2 3.34Å; Y607-I617 HydrophobicContact CD2-CD1 3.6Å; Y607-I617 HydrophobicContact CE2-CD1 4.03Å; Y607-N633 VanDerWaalsContact C-ND2 3.3Å; Y607-N633 PolarHBondContact O-ND2 3.34Å
608S69.4Low65.1Low60 Ų6075.3 Ų75.342%0.4234%0.344SS..  trans-61.5146.7175.284.50000110.2K610 S611 F614S608-K610 PolarHBondContact O-N 3.5Å; S608-K610 PolarHBondContact OG-N 3.28Å; S608-S611 WeakPolarHBondContact O-CB 3.16Å; S608-S611 PolarHBondContact O-N 2.95Å; S608-S611 PolarHBondContact O-OG 3.04Å; S608-S611 PolarHBondContact OG-N 3.42Å; S608-F614 WeakPolarHBondContact O-CB 3.45Å
609C71.4Confident66.4Low63 Ų6367.5 Ų67.543%0.42633%0.325SS..THydrogen-bonded Turntrans-56.5-13.4174.756.80000114F614C609-F614 HydrophobicContact CB-CE1 4.34Å; C609-F614 HydrophobicContact CB-CZ 4.35Å
610K75.6Confident67.2Low174 Ų17466.5 Ų66.576%0.75732%0.32SS*.THydrogen-bonded Turntrans-96.1-11.3177.2-60.4-176-178.2178.60114.2S608S608-K610 PolarHBondContact O-N 3.5Å; S608-K610 PolarHBondContact OG-N 3.28Å
611S75.7Confident68Low20 Ų2060.1 Ų60.114%0.1429%0.292CS..SBendtrans-74.2151.7-176.766.50000112Y607 S608 E613 F614 K615Y607-S611 WeakPolarHBondContact CB-OG 3.5Å; S608-S611 WeakPolarHBondContact O-CB 3.16Å; S608-S611 PolarHBondContact O-N 2.95Å; S608-S611 PolarHBondContact O-OG 3.04Å; S608-S611 PolarHBondContact OG-N 3.42Å; S611-E613 WeakPolarHBondContact CB-OE2 3.45Å; S611-E613 PolarHBondContact O-N 3.48Å; S611-F614 PolarHBondContact O-N 3.47Å; S611-F614 WeakPolarHBondContact OG-CB 3.34Å; S611-F614 PolarHBondContact OG-N 3.49Å; S611-F614 VanDerWaalsContact OG-N 3.09Å; S611-K615 WeakPolarHBondContact O-CG 3.01Å; S611-K615 PolarHBondContact O-N 2.87Å
612E74.3Confident68.8Low102 Ų10267.1 Ų67.148%0.47732%0.321SS..Hα-helixtrans-68-30.4175-74.4-57.513300111K615 R616E612-K615 PolarHBondContact O-N 3.02Å; E612-K615 IonicContact OE1-NZ 2.88Å; E612-K615 PolarHBondContact OE1-NZ 3.06Å; E612-R616 WeakPolarHBondContact O-CB 3.23Å; E612-R616 WeakPolarHBondContact O-CG 3.35Å; E612-R616 PolarHBondContact O-N 2.77Å
613E67.4Low69.3Low82 Ų8272.2 Ų72.238%0.38334%0.344SS..Hα-helixtrans-62.9-44.9174.8-64.677-169.700111.5Y607 S611 K615 R616 I617Y607-E613 HydrophobicContact CD1-CB 3.5Å; Y607-E613 HydrophobicContact CD1-CG 4.03Å; Y607-E613 HydrophobicContact CD2-CB 3.8Å; Y607-E613 HydrophobicContact CE1-CB 3.54Å; Y607-E613 HydrophobicContact CE1-CG 3.64Å; Y607-E613 HydrophobicContact CE2-CB 3.86Å; Y607-E613 HydrophobicContact CG-CB 3.66Å; S611-E613 WeakPolarHBondContact CB-OE2 3.45Å; S611-E613 PolarHBondContact O-N 3.48Å; E613-K615 VanDerWaalsContact C-N 3.33Å; E613-K615 PolarHBondContact O-N 3.35Å; E613-R616 PolarHBondContact O-N 3.49Å; E613-I617 WeakPolarHBondContact O-CG1 3.41Å; E613-I617 PolarHBondContact O-N 3.19Å
614F71.1Confident69.3Low28 Ų2875.4 Ų75.412%0.12336%0.361CS..Hα-helixtrans-60.2-43.3174-173.6-84.1000111.8T605 Y607 S608 C609 S611 I617 Y618 V631T605-F614 HydrophobicContact CG2-CD2 3.48Å; T605-F614 VanDerWaalsContact CG2-CD2 3.48Å; T605-F614 HydrophobicContact CG2-CE2 3.68Å; Y607-F614 WeakPolarHBondContact O-CD2 3.34Å; S608-F614 WeakPolarHBondContact O-CB 3.45Å; C609-F614 HydrophobicContact CB-CE1 4.34Å; C609-F614 HydrophobicContact CB-CZ 4.35Å; S611-F614 PolarHBondContact O-N 3.47Å; S611-F614 WeakPolarHBondContact OG-CB 3.34Å; S611-F614 PolarHBondContact OG-N 3.49Å; S611-F614 VanDerWaalsContact OG-N 3.09Å; F614-I617 PolarHBondContact O-N 2.85Å; F614-Y618 PolarHBondContact O-N 3.15Å; F614-V631 HydrophobicContact CD2-CG1 4.26Å; F614-V631 HydrophobicContact CE2-CG1 3.74Å; F614-V631 HydrophobicContact CZ-CB 4.26Å; F614-V631 HydrophobicContact CZ-CG1 3.94Å; F614-V631 WeakPolarHBondContact CZ-O 3.47Å
615K77.8Confident69.3Low103 Ų10377.5 Ų77.545%0.44839%0.386SS..Hα-helixtrans-65.7-37.9176.9-65.3176.6-165.8166.60112.1S611 E612 E613 Y618 A619S611-K615 WeakPolarHBondContact O-CG 3.01Å; S611-K615 PolarHBondContact O-N 2.87Å; E612-K615 PolarHBondContact O-N 3.02Å; E612-K615 IonicContact OE1-NZ 2.88Å; E612-K615 PolarHBondContact OE1-NZ 3.06Å; E613-K615 VanDerWaalsContact C-N 3.33Å; E613-K615 PolarHBondContact O-N 3.35Å; K615-Y618 PolarHBondContact O-N 3.16Å; K615-A619 VanDerWaalsContact O-CB 3.32Å; K615-A619 WeakPolarHBondContact O-CB 3.49Å; K615-A619 PolarHBondContact O-N 3.04Å
616R74.5Confident69.4Low148 Ų14878.3 Ų78.356%0.55839%0.39SS*.Hα-helixtrans-63.8-44.4175.6-78.8-179.2-167.4174.95.6111.8E612 E613 Y618 A619 Q620E612-R616 WeakPolarHBondContact O-CB 3.23Å; E612-R616 WeakPolarHBondContact O-CG 3.35Å; E612-R616 PolarHBondContact O-N 2.77Å; E613-R616 PolarHBondContact O-N 3.49Å; R616-Y618 VanDerWaalsContact C-N 3.28Å; R616-Y618 PolarHBondContact O-N 3.48Å; R616-A619 PolarHBondContact O-N 3.35Å; R616-Q620 WeakPolarHBondContact O-CB 3.41Å; R616-Q620 PolarHBondContact O-N 2.89Å
617I68.2Low69.3Low7 Ų782.2 Ų82.24%0.03641%0.406CS..Hα-helixtrans-56.9-45.9175.8-65.4162.4000110.7T580 L603 Y607 E613 F614 A621 V631T580-I617 HydrophobicContact CG2-CB 4.12Å; T580-I617 HydrophobicContact CG2-CG1 3.7Å; L603-I617 HydrophobicContact CD2-CG2 4.04Å; Y607-I617 HydrophobicContact CD2-CD1 3.6Å; Y607-I617 HydrophobicContact CE2-CD1 4.03Å; E613-I617 WeakPolarHBondContact O-CG1 3.41Å; E613-I617 PolarHBondContact O-N 3.19Å; F614-I617 PolarHBondContact O-N 2.85Å; I617-A621 WeakPolarHBondContact O-CB 3.37Å; I617-A621 PolarHBondContact O-N 2.99Å; I617-V631 HydrophobicContact CG2-CG1 4.11Å; I617-V631 HydrophobicContact CG2-CG2 4.12Å
618Y71.1Confident69.4Low134 Ų13483.1 Ų83.153%0.52542%0.417SS..Hα-helixtrans-66-42.8178.5-168.9-91.8000112.7F614 K615 R616 K622 V631F614-Y618 PolarHBondContact O-N 3.15Å; K615-Y618 PolarHBondContact O-N 3.16Å; R616-Y618 VanDerWaalsContact C-N 3.28Å; R616-Y618 PolarHBondContact O-N 3.48Å; Y618-K622 PolarHBondContact O-N 3.29Å; Y618-V631 HydrophobicContact CD2-CG2 4.18Å
619A75.5Confident69Low47 Ų4781.6 Ų81.639%0.38840%0.403SS..Hα-helixtrans-66-43.517800000112.1K615 R616 K622 E623K615-A619 VanDerWaalsContact O-CB 3.32Å; K615-A619 WeakPolarHBondContact O-CB 3.49Å; K615-A619 PolarHBondContact O-N 3.04Å; R616-A619 PolarHBondContact O-N 3.35Å; A619-K622 WeakPolarHBondContact O-CB 3.4Å; A619-K622 PolarHBondContact O-N 2.68Å; A619-E623 PolarHBondContact O-N 3.11Å
620Q69.1Low69Low41 Ų4181.3 Ų81.319%0.19240%0.397CS..Hα-helixtrans-65.5-45-179.9-165.167.949.700111.5T580 V584 R616 K622 E623 D624T580-Q620 HydrophobicContact CG2-CB 3.93Å; T580-Q620 HydrophobicContact CG2-CG 4.13Å; V584-Q620 HydrophobicContact CG2-CG 4.33Å; R616-Q620 WeakPolarHBondContact O-CB 3.41Å; R616-Q620 PolarHBondContact O-N 2.89Å; Q620-K622 PolarHBondContact O-N 3.44Å; Q620-E623 PolarHBondContact O-N 3.05Å; Q620-E623 VanDerWaalsContact O-N 3.15Å; Q620-D624 PolarHBondContact NE2-OD2 2.91Å; Q620-D624 PolarHBondContact O-N 2.59Å
621A66.8Low68.6Low5 Ų573.6 Ų73.64%0.04137%0.365CS..Hα-helixtrans-56.8-40174.500000111.5I617 V626 I629I617-A621 WeakPolarHBondContact O-CB 3.37Å; I617-A621 PolarHBondContact O-N 2.99Å; A621-V626 HydrophobicContact CB-CB 4.4Å; A621-V626 VanDerWaalsContact O-CB 3.24Å; A621-V626 WeakPolarHBondContact O-CB 3.47Å; A621-V626 PolarHBondContact O-N 3.31Å; A621-I629 HydrophobicContact CB-CD1 4.24Å; A621-I629 HydrophobicContact CB-CG2 4.11Å
622K69Low68.3Low162 Ų16276.3 Ų76.370%0.70437%0.372SS*.Hα-helixtrans-70-38.4177-169.8177.3-179.5-178.60113Y618 A619 Q620 D624 G625Y618-K622 PolarHBondContact O-N 3.29Å; A619-K622 WeakPolarHBondContact O-CB 3.4Å; A619-K622 PolarHBondContact O-N 2.68Å; Q620-K622 PolarHBondContact O-N 3.44Å; K622-D624 VanDerWaalsContact C-N 3.34Å; K622-G625 PolarHBondContact O-N 3.23Å
623E70.2Confident68.2Low149 Ų14972.6 Ų72.670%0.69636%0.355SS*.Hα-helixtrans-66.1-35176.3-78.9-178.3177.200112.6A619 Q620 G625A619-E623 PolarHBondContact O-N 3.11Å; Q620-E623 PolarHBondContact O-N 3.05Å; Q620-E623 VanDerWaalsContact O-N 3.15Å; E623-G625 VanDerWaalsContact C-N 3.25Å; E623-G625 PolarHBondContact O-N 3.32Å
624D63.8Low67.9Low78 Ų7869.6 Ų69.642%0.41734%0.343SS..THydrogen-bonded Turntrans-86.313.1-178.6-72-44000113.7V584 Q620 K622 V626V584-D624 HydrophobicContact CG1-CB 3.33Å; V584-D624 WeakPolarHBondContact CG1-OD2 3.4Å; Q620-D624 PolarHBondContact NE2-OD2 2.91Å; Q620-D624 PolarHBondContact O-N 2.59Å; K622-D624 VanDerWaalsContact C-N 3.34Å; D624-V626 VanDerWaalsContact C-N 3.27Å; D624-V626 HydrophobicContact CB-CG2 4.46Å; D624-V626 PolarHBondContact O-N 2.96Å
625G62.7Low67.3Low57 Ų5770.2 Ų70.259%0.58836%0.357SS*.THydrogen-bonded Turntrans70.421.5174.800000114.3K622 E623 E627K622-G625 PolarHBondContact O-N 3.23Å; E623-G625 VanDerWaalsContact C-N 3.25Å; E623-G625 PolarHBondContact O-N 3.32Å; G625-E627 VanDerWaalsContact C-N 3.35Å; G625-E627 PolarHBondContact O-N 2.9Å
626V62.1Low66.7Low16 Ų1669.1 Ų69.110%0.09736%0.356CS..  trans-80.185.2175.6178.30000109.4V584 Y587 A621 D624 I629V584-V626 HydrophobicContact CG1-CG2 4.02Å; Y587-V626 HydrophobicContact CD1-CB 4.07Å; Y587-V626 HydrophobicContact CD1-CG1 3.61Å; Y587-V626 HydrophobicContact CD1-CG2 3.38Å; Y587-V626 HydrophobicContact CE1-CB 3.63Å; Y587-V626 HydrophobicContact CE1-CG1 2.97Å; Y587-V626 HydrophobicContact CE1-CG2 3.4Å; Y587-V626 HydrophobicContact CE2-CG1 4.12Å; Y587-V626 HydrophobicContact CG-CG1 4.39Å; Y587-V626 HydrophobicContact CG-CG2 4.5Å; A621-V626 HydrophobicContact CB-CB 4.4Å; A621-V626 VanDerWaalsContact O-CB 3.24Å; A621-V626 WeakPolarHBondContact O-CB 3.47Å; A621-V626 PolarHBondContact O-N 3.31Å; D624-V626 VanDerWaalsContact C-N 3.27Å; D624-V626 HydrophobicContact CB-CG2 4.46Å; D624-V626 PolarHBondContact O-N 2.96Å; V626-I629 HydrophobicContact CB-CD1 4.47Å; V626-I629 HydrophobicContact CG1-CB 3.88Å; V626-I629 HydrophobicContact CG1-CD1 3.46Å; V626-I629 VanDerWaalsContact CG1-CD1 3.46Å; V626-I629 HydrophobicContact CG1-CG1 3.55Å
627E58.6Low66.1Low166 Ų16663.9 Ų63.978%0.77634%0.337SS*.THydrogen-bonded Turntrans-74.7136.8168.6-61.8-175.1171.100108.8G625G625-E627 VanDerWaalsContact C-N 3.35Å; G625-E627 PolarHBondContact O-N 2.9Å
628D63.2Low65.6Low104 Ų10465.7 Ų65.756%0.55634%0.344SS*.THydrogen-bonded Turntrans77.736-177.2-61-34.7000118.5Q600 V601Q600-D628 HydrophobicContact CG-CB 3.88Å; V601-D628 PolarHBondContact N-O 3.31Å
629I62Low65.1Low27 Ų2761.5 Ų61.514%0.13834%0.338CS..EExtended strand (participates in β ladder)trans-93.4128.2164.2-102.8-177.9000112.1Y587 V601 L603 A621 V626 V631Y587-I629 HydrophobicContact CE2-CG1 4.48Å; V601-I629 HydrophobicContact CB-CG1 4.18Å; V601-I629 HydrophobicContact CG1-CG1 4.26Å; V601-I629 CarbonylContact O-C 3.56Å; V601-I629 WeakPolarHBondContact O-CA 3.28Å; L603-I629 HydrophobicContact CD1-CD1 4.15Å; A621-I629 HydrophobicContact CB-CD1 4.24Å; A621-I629 HydrophobicContact CB-CG2 4.11Å; V626-I629 HydrophobicContact CB-CD1 4.47Å; V626-I629 HydrophobicContact CG1-CB 3.88Å; V626-I629 HydrophobicContact CG1-CD1 3.46Å; V626-I629 VanDerWaalsContact CG1-CD1 3.46Å; V626-I629 HydrophobicContact CG1-CG1 3.55Å; I629-V631 HydrophobicContact CG2-CG2 3.41Å; I629-V631 VanDerWaalsContact CG2-CG2 3.41Å
630D69.6Low64.5Low57 Ų5764.4 Ų64.431%0.30534%0.343SS..EExtended strand (participates in β ladder)trans-106.596.3170.4-179.19.7000109V601 I602 L603 R632V601-D630 PolarHBondContact O-N 3.24Å; I602-D630 CarbonylContact C-O 3.59Å; I602-D630 WeakPolarHBondContact CA-O 3.41Å; I602-D630 HydrophobicContact CG1-CB 4.12Å; L603-D630 PolarHBondContact N-O 3.36Å; D630-R632 WeakPolarHBondContact OD1-CG 3.26Å; D630-R632 IonicContact OD1-NE 2.72Å; D630-R632 PolarHBondContact OD1-NE 3.02Å; D630-R632 IonicContact OD2-CZ 3.86Å; D630-R632 VanDerWaalsContact OD2-CZ 3.27Å; D630-R632 IonicContact OD2-NE 3.13Å; D630-R632 PolarHBondContact OD2-NE 3.38Å; D630-R632 IonicContact OD2-NH2 3.91Å; D630-R632 PolarHBondContact OD2-NH2 3.15Å
631V68.8Low63.6Low13 Ų1364 Ų648%0.07934%0.34CS..EExtended strand (participates in β ladder)trans-83.4121.4177.6-171.30000109.2L603 T605 F614 I617 Y618 I629L603-V631 HydrophobicContact CB-CG2 4.35Å; L603-V631 HydrophobicContact CD2-CG1 4.27Å; L603-V631 CarbonylContact O-C 3.45Å; L603-V631 WeakPolarHBondContact O-CA 3.43Å; T605-V631 HydrophobicContact CG2-CG1 3.9Å; F614-V631 HydrophobicContact CD2-CG1 4.26Å; F614-V631 HydrophobicContact CE2-CG1 3.74Å; F614-V631 HydrophobicContact CZ-CB 4.26Å; F614-V631 HydrophobicContact CZ-CG1 3.94Å; F614-V631 WeakPolarHBondContact CZ-O 3.47Å; I617-V631 HydrophobicContact CG2-CG1 4.11Å; I617-V631 HydrophobicContact CG2-CG2 4.12Å; Y618-V631 HydrophobicContact CD2-CG2 4.18Å; I629-V631 HydrophobicContact CG2-CG2 3.41Å; I629-V631 VanDerWaalsContact CG2-CG2 3.41Å
632R69Low62.9Low77 Ų7768.2 Ų68.229%0.29136%0.36SS..EExtended strand (participates in β ladder)trans-126.4144.8177.9-60.4-170.3-178.4-1472.8112.1I602 L603 L604 T605 D630 F637 E640I602-R632 HydrophobicContact CG2-CG 4.33Å; L603-R632 PolarHBondContact O-N 3.02Å; L604-R632 WeakPolarHBondContact CA-O 3.46Å; L604-R632 HydrophobicContact CD2-CB 3.94Å; T605-R632 PolarHBondContact N-O 3.21Å; D630-R632 WeakPolarHBondContact OD1-CG 3.26Å; D630-R632 IonicContact OD1-NE 2.72Å; D630-R632 PolarHBondContact OD1-NE 3.02Å; D630-R632 IonicContact OD2-CZ 3.86Å; D630-R632 VanDerWaalsContact OD2-CZ 3.27Å; D630-R632 IonicContact OD2-NE 3.13Å; D630-R632 PolarHBondContact OD2-NE 3.38Å; D630-R632 IonicContact OD2-NH2 3.91Å; D630-R632 PolarHBondContact OD2-NH2 3.15Å; R632-F637 HydrophobicContact CB-CB 4.4Å; R632-E640 IonicContact NH1-OE2 2.96Å; R632-E640 PolarHBondContact NH1-OE2 3.31Å
633N71.3Confident62.3Low23 Ų2368.4 Ų68.412%0.12336%0.361CS..EExtended strand (participates in β ladder)trans-67.5133.8165.5177.6-91.6000109T605 D606 Y607 G635 D636 F637T605-N633 CarbonylContact O-C 3.59Å; T605-N633 VanDerWaalsContact O-CA 3.31Å; T605-N633 WeakPolarHBondContact O-CA 3.35Å; D606-N633 PolarHBondContact O-ND2 2.99Å; Y607-N633 VanDerWaalsContact C-ND2 3.3Å; Y607-N633 PolarHBondContact O-ND2 3.34Å; N633-G635 VanDerWaalsContact C-N 3.3Å; N633-G635 PolarHBondContact O-N 2.95Å; N633-G635 VanDerWaalsContact OD1-CA 3.28Å; N633-G635 WeakPolarHBondContact OD1-CA 3.44Å; N633-G635 PolarHBondContact OD1-N 3.39Å; N633-D636 HydrophobicContact CB-CB 4.1Å; N633-D636 WeakPolarHBondContact CB-OD2 3.4Å; N633-D636 PolarHBondContact O-N 3.34Å; N633-D636 PolarHBondContact OD1-N 3.48Å; N633-D636 VanDerWaalsContact OD1-N 3.08Å; N633-F637 WeakPolarHBondContact O-CB 3.42Å; N633-F637 PolarHBondContact O-N 3.37Å
634V61.1Low61.3Low20 Ų2070.1 Ų70.112%0.12137%0.367CS..Hα-helixtrans-56.2-45.41801700000111L604 T605 D606 F637 Y638L604-V634 HydrophobicContact CB-CG2 3.81Å; T605-V634 WeakPolarHBondContact O-CG2 3.2Å; T605-V634 PolarHBondContact O-N 2.94Å; D606-V634 WeakPolarHBondContact OD1-CG2 3.39Å; V634-F637 PolarHBondContact O-N 2.91Å; V634-Y638 HydrophobicContact CG1-CD2 3.62Å; V634-Y638 HydrophobicContact CG1-CE2 3.55Å; V634-Y638 WeakPolarHBondContact O-CD2 3.4Å; V634-Y638 PolarHBondContact O-N 3.08Å
635G59.4Low60.2Low41 Ų4172.2 Ų72.242%0.42337%0.374SS..Hα-helixtrans-63.7-45.9179.300000113.1N633 Y638 A639N633-G635 VanDerWaalsContact C-N 3.3Å; N633-G635 PolarHBondContact O-N 2.95Å; N633-G635 VanDerWaalsContact OD1-CA 3.28Å; N633-G635 WeakPolarHBondContact OD1-CA 3.44Å; N633-G635 PolarHBondContact OD1-N 3.39Å; G635-Y638 PolarHBondContact O-N 3.35Å; G635-A639 WeakPolarHBondContact O-CB 3.36Å; G635-A639 PolarHBondContact O-N 3Å
636D64.9Low59Low79 Ų7981.4 Ų81.442%0.42239%0.393SS..Hα-helixtrans-63.7-42.8178.2-66.6-26.3000111.4N633 Y638 A639 E640N633-D636 HydrophobicContact CB-CB 4.1Å; N633-D636 WeakPolarHBondContact CB-OD2 3.4Å; N633-D636 PolarHBondContact O-N 3.34Å; N633-D636 PolarHBondContact OD1-N 3.48Å; N633-D636 VanDerWaalsContact OD1-N 3.08Å; D636-Y638 PolarHBondContact O-N 3.1Å; D636-A639 PolarHBondContact O-N 2.97Å; D636-E640 PolarHBondContact O-N 3.07Å
637F63Low58.8Low38 Ų3884.7 Ų84.717%0.16741%0.407CS..Hα-helixtrans-59.3-45.6175.3177.5-97.3000111.9L604 R632 N633 V634 E640 W641L604-F637 HydrophobicContact CD1-CD1 4.22Å; L604-F637 HydrophobicContact CD1-CE1 4.33Å; L604-F637 HydrophobicContact CD2-CB 4.06Å; L604-F637 HydrophobicContact CD2-CD1 4.17Å; L604-F637 HydrophobicContact CD2-CD2 4.13Å; L604-F637 HydrophobicContact CD2-CG 3.85Å; R632-F637 HydrophobicContact CB-CB 4.4Å; N633-F637 WeakPolarHBondContact O-CB 3.42Å; N633-F637 PolarHBondContact O-N 3.37Å; V634-F637 PolarHBondContact O-N 2.91Å; F637-E640 PolarHBondContact O-N 2.97Å; F637-W641 WeakPolarHBondContact O-CB 3.42Å; F637-W641 PolarHBondContact O-N 3.01Å
638Y56.3Low58.8Low45 Ų4580.4 Ų80.418%0.17639%0.388CS..Hα-helixtrans-66-35.2175.5-83.6-67.8000112.7A545 V634 G635 D636 W641 I642A545-Y638 HydrophobicContact CB-CE1 4.09Å; V634-Y638 HydrophobicContact CG1-CD2 3.62Å; V634-Y638 HydrophobicContact CG1-CE2 3.55Å; V634-Y638 WeakPolarHBondContact O-CD2 3.4Å; V634-Y638 PolarHBondContact O-N 3.08Å; G635-Y638 PolarHBondContact O-N 3.35Å; D636-Y638 PolarHBondContact O-N 3.1Å; Y638-W641 HydrophobicContact CD1-CE3 4.19Å; Y638-W641 WeakPolarHBondContact O-CB 3.44Å; Y638-W641 PolarHBondContact O-N 3.41Å; Y638-I642 WeakPolarHBondContact O-CG1 3.43Å; Y638-I642 PolarHBondContact O-N 3.5Å
639A61.3Low58.6Low47 Ų4779.1 Ų79.139%0.38838%0.379SS..Hα-helixtrans-69.7-36.9177.800000112.8G635 D636 K643G635-A639 WeakPolarHBondContact O-CB 3.36Å; G635-A639 PolarHBondContact O-N 3Å; D636-A639 PolarHBondContact O-N 2.97Å; A639-K643 WeakPolarHBondContact O-CG 3.44Å; A639-K643 PolarHBondContact O-N 3.1Å
640E61.8Low58.4Low107 Ų10782.2 Ų82.250%0.539%0.393SS..Hα-helixtrans-66.3-37.7170.3-73.6-173.7167.600112R632 D636 F637 K643R632-E640 IonicContact NH1-OE2 2.96Å; R632-E640 PolarHBondContact NH1-OE2 3.31Å; D636-E640 PolarHBondContact O-N 3.07Å; F637-E640 PolarHBondContact O-N 2.97Å; E640-K643 PolarHBondContact O-N 3.03Å
641W51.9Low57.7Low34 Ų3483.8 Ų83.813%0.12940%0.398CS..Hα-helixtrans-63.4-48.6177.517672.7000112.2Q544 F637 Y638 K643 K644 E645Q544-W641 HydrophobicContact CB-CH2 4.28Å; Q544-W641 HydrophobicContact CB-CZ2 4.41Å; F637-W641 WeakPolarHBondContact O-CB 3.42Å; F637-W641 PolarHBondContact O-N 3.01Å; Y638-W641 HydrophobicContact CD1-CE3 4.19Å; Y638-W641 WeakPolarHBondContact O-CB 3.44Å; Y638-W641 PolarHBondContact O-N 3.41Å; W641-K643 PolarHBondContact O-N 2.63Å; W641-K644 PolarHBondContact O-N 3.2Å; W641-E645 VanDerWaalsContact CZ2-OE2 3.32Å; W641-E645 WeakPolarHBondContact CZ2-OE2 3.42Å
642I51Low56.9Low92 Ų9288.5 Ų88.547%0.47242%0.419SS..Hα-helixtrans-58.5-32.8177.8-69.2170.4000111.6Y638 K644 Y646Y638-I642 WeakPolarHBondContact O-CG1 3.43Å; Y638-I642 PolarHBondContact O-N 3.5Å; I642-K644 VanDerWaalsContact C-N 3.27Å; I642-K644 PolarHBondContact O-N 3.45Å; I642-Y646 HydrophobicContact CG2-CD2 4.46Å
643K57.4Low56.1Low166 Ų16689.3 Ų89.372%0.72243%0.429SS*.THydrogen-bonded Turntrans-74.5-9.4178.3-73.7177.6-178.7176.60114.7A639 E640 W641A639-K643 WeakPolarHBondContact O-CG 3.44Å; A639-K643 PolarHBondContact O-N 3.1Å; E640-K643 PolarHBondContact O-N 3.03Å; W641-K643 PolarHBondContact O-N 2.63Å
644K47.9Very low54.9Low186 Ų18694.4 Ų94.481%0.80945%0.452SS*.THydrogen-bonded Turntrans-100.7-16.5178.3-77-175.6175.5179.30113.6W641 I642W641-K644 PolarHBondContact O-N 3.2Å; I642-K644 VanDerWaalsContact C-N 3.27Å; I642-K644 PolarHBondContact O-N 3.45Å
645E41.9Very low54.4Low121 Ų121100.6 Ų100.657%0.56548%0.48SS*.  trans-94.3-2.1176.3-79-169.7162.300113.8W641W641-E645 VanDerWaalsContact CZ2-OE2 3.32Å; W641-E645 WeakPolarHBondContact CZ2-OE2 3.42Å
646Y35.9Very low53.9Low251 Ų251106 Ų10698%0.98449%0.485SS*.  trans-124.10168.3-69.7-80.3000109.5I642I642-Y646 HydrophobicContact CG2-CD2 4.46Å

Retrieved 646 of 646 residues in 151.9 ms (Link to these results)