A0A077ZKZ3_TRITR Loading...

MFS 1 and MFS 1 like domain containing protein

AlphaFold DB , UniProt , Accession A0A077ZKZ3, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 673 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.6	Very low	35.2	Very low	246 Å²	246	157.5 Å²	157.5	100%	1.212	83%	0.827	S	S	*	*				0	71.7	0	-68.6	175.9	173.8	0	0	105.6
2	D	32.9	Very low	34.7	Very low	134 Å²	134	159.5 Å²	159.5	72%	0.717	83%	0.829	S	S	*	*				73.3	139.1	66.4	-148.4	7.7	0	0	0	113.8
3	T	34.3	Very low	34.4	Very low	127 Å²	127	158.5 Å²	158.5	78%	0.779	82%	0.818	S	S	*	*			trans	91	91.5	-177	68.4	0	0	0	0	115.8
4	R	33.6	Very low	34.1	Very low	243 Å²	243	162 Å²	162	92%	0.917	82%	0.818	S	S	*	*				69.5	125.5	57.8	-74.5	-170	177.4	174.5	1.1	116.1
5	G	39.9	Very low	33.8	Very low	71 Å²	71	157.4 Å²	157.4	73%	0.732	81%	0.807	S	S	*	*			trans	154.5	128.2	150.4	0	0	0	0	0	110
6	Q	36.8	Very low	33.6	Very low	197 Å²	197	156.6 Å²	156.6	92%	0.921	81%	0.805	S	S	*	*			cis	-173	137.9	-4	-135.5	164	-15	0	0	105.4
7	Q	33.6	Very low	33.6	Very low	167 Å²	167	155.9 Å²	155.9	78%	0.78	81%	0.809	S	S	*	*			trans	-85.9	172.7	175.5	-135.8	177.3	13.5	0	0	110.1
8	P	38	Very low	33.3	Very low	113 Å²	113	152.8 Å²	152.8	73%	0.734	81%	0.81	S	S	*	*				-157	142.7	81	37.6	-15	0	0	0	119.7
9	T	32.4	Very low	33.3	Very low	116 Å²	116	148.9 Å²	148.9	71%	0.712	81%	0.81	S	S	*	*			trans	29.8	134.4	136.2	58.8	0	0	0	0	125.7
10	A	35.5	Very low	33	Very low	81 Å²	81	150 Å²	150	67%	0.669	81%	0.809	S	S	*	*				161.8	129.4	116.8	0	0	0	0	0	109.3
11	Y	32	Very low	32.8	Very low	237 Å²	237	153 Å²	153	93%	0.929	81%	0.811	S	S	*	*				-160.3	148.1	57.6	-94.8	-92.5	0	0	0	112
12	Q	28.9	Very low	32.5	Very low	182 Å²	182	146.1 Å²	146.1	85%	0.85	79%	0.787	S	S	*	*			trans	-102.1	166.5	-179.6	-120.9	171	-29	0	0	111.9
13	Q	30.4	Very low	32.3	Very low	146 Å²	146	149.7 Å²	149.7	68%	0.682	80%	0.796	S	S	*	*			trans	116.7	103.5	134.9	-137.5	166.8	-17.2	0	0	117.2
14	Y	30.9	Very low	32.1	Very low	208 Å²	208	146.9 Å²	146.9	82%	0.816	79%	0.792	S	S	*	*				173.8	122.9	103.1	-99.2	-80.2	0	0	0	111.4
15	S	28.7	Very low	32.1	Very low	93 Å²	93	144.9 Å²	144.9	65%	0.65	79%	0.793	S	S	*	*			trans	-133.9	159.3	167.4	69.4	0	0	0	0	109.8
16	N	30.3	Very low	31.5	Very low	145 Å²	145	151 Å²	151	78%	0.775	80%	0.802	S	S	*	*			trans	96.2	119.2	166	-50.2	-15.3	0	0	0	115.9
17	V	33.7	Very low	31.3	Very low	144 Å²	144	146.6 Å²	146.6	87%	0.873	80%	0.8	S	S	*	*				-167	132.6	98.3	167.9	0	0	0	0	108.8
18	A	29.7	Very low	31.1	Very low	101 Å²	101	146 Å²	146	84%	0.835	80%	0.801	S	S	*	*			trans	-90.6	152.9	173.1	0	0	0	0	0	111.5
19	G	31.9	Very low	30.8	Very low	78 Å²	78	146.6 Å²	146.6	80%	0.804	80%	0.802	S	S	*	*			trans	-174.7	117	169.5	0	0	0	0	0	112.4
20	E	27.1	Very low	30.7	Very low	170 Å²	170	147.5 Å²	147.5	79%	0.794	80%	0.802	S	S	*	*			trans	-60.4	153.7	-179.7	-68	155.8	123	0	0	114.4
21	Y	30.1	Very low	30.5	Very low	214 Å²	214	152.1 Å²	152.1	84%	0.839	81%	0.81	S	S	*	*				166	118.7	113.5	-101.2	-89.4	0	0	0	113.1
22	S	31.5	Very low	30.6	Very low	102 Å²	102	151 Å²	151	71%	0.713	80%	0.804	S	S	*	*			trans	52.6	118.5	134.4	-157.8	0	0	0	0	123.7
23	K	29.2	Very low	31	Very low	209 Å²	209	151.3 Å²	151.3	91%	0.909	81%	0.806	S	S	*	*			trans	11.2	132.5	140.7	-70.8	-179.9	174.3	179	0	119.8
24	G	30.8	Very low	31.3	Very low	68 Å²	68	153.5 Å²	153.5	70%	0.701	82%	0.815	S	S	*	*			trans	163.1	101.8	150.6	0	0	0	0	0	115.1
25	E	32.4	Very low	31.9	Very low	201 Å²	201	149.1 Å²	149.1	94%	0.939	81%	0.812	S	S	*	*			trans	54.9	138	144	-77.7	159.4	130.5	0	0	123.9
26	E	27.1	Very low	32.4	Very low	198 Å²	198	150.3 Å²	150.3	93%	0.925	82%	0.818	S	S	*	*			trans	-65.3	135.8	177.3	-61.5	169.8	144.3	0	0	112.8
27	A	32.6	Very low	32.9	Very low	105 Å²	105	149.6 Å²	149.6	87%	0.868	82%	0.821	S	S	*	*			trans	-152.2	132	153.9	0	0	0	0	0	112.3
28	I	30.9	Very low	33.1	Very low	155 Å²	155	151 Å²	151	80%	0.795	82%	0.823	S	S	*	*			trans	-73.6	140.8	-173.4	-76.6	165.4	0	0	0	113
29	V	30.2	Very low	33.6	Very low	126 Å²	126	155.6 Å²	155.6	76%	0.764	83%	0.827	S	S	*	*			trans	74.8	121.7	147.8	174.1	0	0	0	0	119.6
30	D	31.3	Very low	33.9	Very low	134 Å²	134	163.1 Å²	163.1	72%	0.717	83%	0.831	S	S	*	*				-173.9	139.8	95.8	-158.9	4.7	0	0	0	111.5
31	E	29.9	Very low	34.7	Very low	178 Å²	178	160 Å²	160	83%	0.832	83%	0.828	S	S	*	*			trans	-101.5	91	-168.9	-168.1	178.9	-174.7	0	0	108.3
32	R	35	Very low	35.4	Very low	214 Å²	214	153 Å²	153	81%	0.808	81%	0.81	S	S	*	*			trans	-172.1	94	168.2	-111.4	179.3	-84.9	-163.6	-0.9	110.8
33	Q	37.6	Very low	36.6	Very low	189 Å²	189	151.9 Å²	151.9	88%	0.883	80%	0.799	S	S	*	*			trans	158.1	81.4	151.9	-89.1	160.2	13.9	0	0	110.8
34	H	36.2	Very low	38	Very low	191 Å²	191	149.3 Å²	149.3	88%	0.884	80%	0.795	S	S	*	*			trans	-134.6	124.7	156.7	-95.2	39.5	0	0	0	108.5
35	P	43.2	Very low	39.2	Very low	116 Å²	116	152 Å²	152	75%	0.753	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-72.2	153.7	-178.3	30	-33	0	0	0	111.4
36	P	39.4	Very low	40.4	Very low	119 Å²	119	148.3 Å²	148.3	77%	0.773	78%	0.775	S	S	*	*	P	Polyproline II helix	trans	-72.8	147.7	-176.4	30.4	-33.4	0	0	0	111.6
37	P	41.5	Very low	41.8	Very low	129 Å²	129	145 Å²	145	84%	0.838	76%	0.758	S	S	*	*	P	Polyproline II helix	trans	-73.1	135.1	177.1	28.9	-31.2	0	0	0	111.5
38	L	38.5	Very low	42.7	Very low	173 Å²	173	142.3 Å²	142.3	91%	0.906	73%	0.732	S	S	*	*	P	Polyproline II helix	trans	-59.6	131.1	174.8	-91.4	132.5	0	0	0	112.4	R40	L38-R40 PolarHBondContact O-N 3.41Å; L38-R40 VanDerWaalsContact O-N 3.15Å
39	H	39	Very low	44.3	Very low	199 Å²	199	139.3 Å²	139.3	92%	0.921	72%	0.721	S	S	*	*			trans	-58.1	109.8	169.4	-104.4	-44.7	0	0	0	111.2
40	R	38.3	Very low	45.5	Very low	236 Å²	236	135.6 Å²	135.6	89%	0.891	71%	0.708	S	S	*	*	P	Polyproline II helix	trans	-86.6	116.9	168.8	-160.3	174.6	-167	175.9	3.1	109	L38 S42	L38-R40 PolarHBondContact O-N 3.41Å; L38-R40 VanDerWaalsContact O-N 3.15Å; R40-S42 PolarHBondContact O-N 3.15Å
41	S	43.9	Very low	46.7	Very low	103 Å²	103	134.6 Å²	134.6	72%	0.72	70%	0.702	S	S	*	*	P	Polyproline II helix	trans	-57.3	126.6	173.8	55.4	0	0	0	0	110.8	T43	S41-T43 PolarHBondContact O-N 3.37Å
42	S	45.1	Very low	47.9	Very low	67 Å²	67	131.6 Å²	131.6	47%	0.469	69%	0.691	S	S	.	*	P	Polyproline II helix	trans	-57.2	130	175.6	46.9	0	0	0	0	110.9	R40 E46	R40-S42 PolarHBondContact O-N 3.15Å; S42-E46 WeakPolarHBondContact CA-OE2 3.24Å
43	T	56.8	Low	48.7	Very low	80 Å²	80	123.3 Å²	123.3	49%	0.491	67%	0.671	S	S	.	*	P	Polyproline II helix	trans	-67.8	148.9	-179.7	60.2	0	0	0	0	109.7	S41 L45 E46 K47	S41-T43 PolarHBondContact O-N 3.37Å; T43-L45 PolarHBondContact O-N 3.49Å; T43-E46 PolarHBondContact N-OE2 3.03Å; T43-E46 PolarHBondContact O-N 3Å; T43-K47 PolarHBondContact O-N 3.06Å
44	L	58.1	Low	49.3	Very low	155 Å²	155	117.1 Å²	117.1	81%	0.812	65%	0.653	S	S	*	*	H	α-helix	trans	-53.1	-28.1	174.9	-77.9	171.4	0	0	0	112.2	K47 S48	L44-K47 PolarHBondContact O-N 3.44Å; L44-S48 PolarHBondContact O-N 3.39Å; L44-S48 PolarHBondContact O-OG 3Å; L44-S48 VanDerWaalsContact O-OG 3.06Å
45	L	55.4	Low	49.6	Very low	125 Å²	125	116.8 Å²	116.8	65%	0.654	64%	0.644	S	S	*	*	H	α-helix	trans	-62.3	-45.9	174.4	-107.4	157	0	0	0	113.1	T43 K47 S48 V49	T43-L45 PolarHBondContact O-N 3.49Å; L45-K47 VanDerWaalsContact C-N 3.34Å; L45-K47 PolarHBondContact O-N 3.22Å; L45-S48 VanDerWaalsContact C-OG 3.32Å; L45-S48 VanDerWaalsContact CA-OG 3.24Å; L45-S48 WeakPolarHBondContact CA-OG 3.21Å; L45-S48 PolarHBondContact O-N 2.73Å; L45-S48 PolarHBondContact O-OG 3.38Å; L45-V49 WeakPolarHBondContact O-CG2 3.49Å; L45-V49 PolarHBondContact O-N 2.91Å
46	E	59.1	Low	49.8	Very low	123 Å²	123	117.2 Å²	117.2	58%	0.575	64%	0.636	S	S	*	*	H	α-helix	trans	-64.3	-38.3	176.6	-78.6	177.2	143	0	0	112.2	S42 T43 V49 G50	S42-E46 WeakPolarHBondContact CA-OE2 3.24Å; T43-E46 PolarHBondContact N-OE2 3.03Å; T43-E46 PolarHBondContact O-N 3Å; E46-V49 PolarHBondContact O-N 2.91Å; E46-G50 PolarHBondContact O-N 2.94Å
47	K	56.9	Low	50.1	Low	129 Å²	129	114.3 Å²	114.3	56%	0.561	62%	0.618	S	S	*	*	H	α-helix	trans	-65.5	-39	174.1	-74.1	-175.2	178.5	179.1	0	111.9	T43 L44 L45 G50 L51	T43-K47 PolarHBondContact O-N 3.06Å; L44-K47 PolarHBondContact O-N 3.44Å; L45-K47 VanDerWaalsContact C-N 3.34Å; L45-K47 PolarHBondContact O-N 3.22Å; K47-G50 PolarHBondContact O-N 2.87Å; K47-L51 PolarHBondContact O-N 2.99Å
48	S	50.6	Low	50.2	Low	48 Å²	48	112.2 Å²	112.2	34%	0.336	61%	0.606	S	S	.	*	H	α-helix	trans	-67.8	-38.1	174.6	45.9	0	0	0	0	113	L44 L45 L51 I52	L44-S48 PolarHBondContact O-N 3.39Å; L44-S48 PolarHBondContact O-OG 3Å; L44-S48 VanDerWaalsContact O-OG 3.06Å; L45-S48 VanDerWaalsContact C-OG 3.32Å; L45-S48 VanDerWaalsContact CA-OG 3.24Å; L45-S48 WeakPolarHBondContact CA-OG 3.21Å; L45-S48 PolarHBondContact O-N 2.73Å; L45-S48 PolarHBondContact O-OG 3.38Å; S48-L51 PolarHBondContact O-N 3.47Å; S48-I52 WeakPolarHBondContact O-CD1 3.44Å; S48-I52 WeakPolarHBondContact O-CG1 3.35Å; S48-I52 PolarHBondContact O-N 3.46Å
49	V	64.5	Low	50.8	Low	92 Å²	92	106.5 Å²	106.5	56%	0.558	58%	0.576	S	S	*	*	H	α-helix	trans	-65.6	-40.3	174.8	173.8	0	0	0	0	110.9	L45 E46 I52 G53	L45-V49 WeakPolarHBondContact O-CG2 3.49Å; L45-V49 PolarHBondContact O-N 2.91Å; E46-V49 PolarHBondContact O-N 2.91Å; V49-I52 PolarHBondContact O-N 2.98Å; V49-G53 PolarHBondContact O-N 3.31Å
50	G	55.4	Low	51.5	Low	47 Å²	47	99.3 Å²	99.3	49%	0.485	55%	0.546	S	S	.	.	H	α-helix	trans	-62.7	-40	173.3	0	0	0	0	0	113.3	E46 K47 G53 A54	E46-G50 PolarHBondContact O-N 2.94Å; K47-G50 PolarHBondContact O-N 2.87Å; G50-G53 PolarHBondContact O-N 3.07Å; G50-A54 WeakPolarHBondContact O-CB 3.09Å; G50-A54 PolarHBondContact O-N 3.46Å
51	L	57.2	Low	52.7	Low	114 Å²	114	95.4 Å²	95.4	60%	0.597	54%	0.536	S	S	*	.	H	α-helix	trans	-66.8	-40.1	174.6	-98.4	158.2	0	0	0	112.6	K47 S48 A54 W55	K47-L51 PolarHBondContact O-N 2.99Å; S48-L51 PolarHBondContact O-N 3.47Å; L51-A54 PolarHBondContact O-N 3.2Å; L51-W55 WeakPolarHBondContact O-CB 3.34Å; L51-W55 PolarHBondContact O-N 3.14Å
52	I	55	Low	53.8	Low	115 Å²	115	92.1 Å²	92.1	59%	0.59	52%	0.518	S	S	*	.	H	α-helix	trans	-65	-42.3	174.4	-67.6	162.6	0	0	0	110.2	S48 V49 W55 H56	S48-I52 WeakPolarHBondContact O-CD1 3.44Å; S48-I52 WeakPolarHBondContact O-CG1 3.35Å; S48-I52 PolarHBondContact O-N 3.46Å; V49-I52 PolarHBondContact O-N 2.98Å; I52-W55 PolarHBondContact O-N 3.18Å; I52-H56 WeakPolarHBondContact O-CB 3.41Å; I52-H56 PolarHBondContact O-N 3.02Å
53	G	50.6	Low	55	Low	39 Å²	39	90.8 Å²	90.8	40%	0.402	51%	0.505	S	S	.	.	H	α-helix	trans	-63.2	-41.2	175	0	0	0	0	0	113	V49 G50 H56 S57	V49-G53 PolarHBondContact O-N 3.31Å; G50-G53 PolarHBondContact O-N 3.07Å; G53-H56 PolarHBondContact O-N 3.47Å; G53-S57 WeakPolarHBondContact O-CB 3.39Å; G53-S57 PolarHBondContact O-N 3.46Å
54	A	50.2	Low	56.1	Low	60 Å²	60	89.4 Å²	89.4	50%	0.496	49%	0.494	S	S	.	.	H	α-helix	trans	-66.8	-40.6	175	0	0	0	0	0	112.2	G50 L51 S57 S58	G50-A54 WeakPolarHBondContact O-CB 3.09Å; G50-A54 PolarHBondContact O-N 3.46Å; L51-A54 PolarHBondContact O-N 3.2Å; A54-S57 PolarHBondContact O-N 2.72Å; A54-S58 PolarHBondContact O-N 3.4Å
55	W	43.5	Very low	57.6	Low	183 Å²	183	86.6 Å²	86.6	69%	0.693	48%	0.479	S	S	*	.	H	α-helix	trans	-62.4	-44.6	172.5	-106.6	78.6	0	0	0	111.7	L51 I52 S57 S58 I59	L51-W55 WeakPolarHBondContact O-CB 3.34Å; L51-W55 PolarHBondContact O-N 3.14Å; I52-W55 PolarHBondContact O-N 3.18Å; W55-S57 PolarHBondContact O-N 3.41Å; W55-S58 PolarHBondContact O-N 3Å; W55-I59 HydrophobicContact CE3-CD1 3.95Å; W55-I59 HydrophobicContact CE3-CG1 4.48Å; W55-I59 HydrophobicContact CZ3-CD1 4.44Å; W55-I59 VanDerWaalsContact O-CG1 3.3Å; W55-I59 WeakPolarHBondContact O-CG1 3.34Å; W55-I59 PolarHBondContact O-N 2.89Å
56	H	46.1	Very low	59.3	Low	126 Å²	126	82 Å²	82	58%	0.583	46%	0.456	S	S	*	.	H	α-helix	trans	-63.2	-39.2	176.9	-166.5	-82.3	0	0	0	112.1	I52 G53 I59 T60	I52-H56 WeakPolarHBondContact O-CB 3.41Å; I52-H56 PolarHBondContact O-N 3.02Å; G53-H56 PolarHBondContact O-N 3.47Å; H56-I59 PolarHBondContact O-N 2.96Å; H56-T60 PolarHBondContact O-N 3.25Å; H56-T60 PolarHBondContact O-OG1 2.94Å
57	S	46.9	Very low	60.7	Low	58 Å²	58	76.2 Å²	76.2	41%	0.406	43%	0.43	S	S	.	.	H	α-helix	trans	-67.1	-34.1	174.2	179.7	0	0	0	0	113.4	G53 A54 W55 T60 K61	G53-S57 WeakPolarHBondContact O-CB 3.39Å; G53-S57 PolarHBondContact O-N 3.46Å; A54-S57 PolarHBondContact O-N 2.72Å; W55-S57 PolarHBondContact O-N 3.41Å; S57-T60 WeakPolarHBondContact CA-OG1 3.27Å; S57-T60 PolarHBondContact O-OG1 3.39Å; S57-T60 VanDerWaalsContact O-OG1 3.06Å; S57-K61 PolarHBondContact O-N 3.35Å
58	S	43.9	Very low	62.3	Low	84 Å²	84	72.7 Å²	72.7	59%	0.587	41%	0.414	S	S	*	.	H	α-helix	trans	-70.1	-40.7	174.9	-166.4	0	0	0	0	111.3	A54 W55 K61 G62	A54-S58 PolarHBondContact O-N 3.4Å; W55-S58 PolarHBondContact O-N 3Å; S58-K61 PolarHBondContact O-N 2.97Å; S58-G62 PolarHBondContact O-N 3.02Å; S58-G62 VanDerWaalsContact O-N 3.11Å
59	I	49.5	Very low	64.4	Low	53 Å²	53	73.3 Å²	73.3	27%	0.272	41%	0.413	S	S	.	.	H	α-helix	trans	-62.1	-46.7	176.3	-72	169.1	0	0	0	111.2	W55 H56 K61 G62 E63	W55-I59 HydrophobicContact CE3-CD1 3.95Å; W55-I59 HydrophobicContact CE3-CG1 4.48Å; W55-I59 HydrophobicContact CZ3-CD1 4.44Å; W55-I59 VanDerWaalsContact O-CG1 3.3Å; W55-I59 WeakPolarHBondContact O-CG1 3.34Å; W55-I59 PolarHBondContact O-N 2.89Å; H56-I59 PolarHBondContact O-N 2.96Å; I59-K61 PolarHBondContact O-N 2.89Å; I59-G62 WeakPolarHBondContact O-CA 3.39Å; I59-G62 PolarHBondContact O-N 2.9Å; I59-G62 VanDerWaalsContact O-N 3.09Å; I59-E63 HydrophobicContact CG2-CG 4.18Å; I59-E63 VanDerWaalsContact CG2-OE1 3.24Å; I59-E63 WeakPolarHBondContact CG2-OE1 3.35Å; I59-E63 WeakPolarHBondContact O-CB 3.46Å; I59-E63 WeakPolarHBondContact O-CG 3.39Å; I59-E63 PolarHBondContact O-N 3.16Å
60	T	54.6	Low	65.8	Low	49 Å²	49	69 Å²	69	30%	0.301	39%	0.387	S	S	.	.	H	α-helix	trans	-63.6	-37.9	-179.6	46.6	0	0	0	0	112.7	H56 S57 G62 E63 L64	H56-T60 PolarHBondContact O-N 3.25Å; H56-T60 PolarHBondContact O-OG1 2.94Å; S57-T60 WeakPolarHBondContact CA-OG1 3.27Å; S57-T60 PolarHBondContact O-OG1 3.39Å; S57-T60 VanDerWaalsContact O-OG1 3.06Å; T60-G62 VanDerWaalsContact C-N 3.34Å; T60-G62 PolarHBondContact O-N 3.42Å; T60-E63 PolarHBondContact O-N 2.81Å; T60-L64 WeakPolarHBondContact O-CD1 3.15Å; T60-L64 PolarHBondContact O-N 3.28Å; T60-L64 VanDerWaalsContact O-N 3.09Å
61	K	63.7	Low	67.6	Low	154 Å²	154	66.7 Å²	66.7	67%	0.67	36%	0.364	S	S	*	.	H	α-helix	trans	-64.3	-38.7	172.7	-72.4	-180	-178.4	176.5	0	112.3	S57 S58 I59 L65	S57-K61 PolarHBondContact O-N 3.35Å; S58-K61 PolarHBondContact O-N 2.97Å; I59-K61 PolarHBondContact O-N 2.89Å; K61-L65 PolarHBondContact O-N 3.42Å
62	G	67.4	Low	69.4	Low	34 Å²	34	63.4 Å²	63.4	35%	0.351	35%	0.345	S	S	.	.	H	α-helix	trans	-66.3	-43.8	175.5	0	0	0	0	0	112.5	S58 I59 T60 L64 L65 V66	S58-G62 PolarHBondContact O-N 3.02Å; S58-G62 VanDerWaalsContact O-N 3.11Å; I59-G62 WeakPolarHBondContact O-CA 3.39Å; I59-G62 PolarHBondContact O-N 2.9Å; I59-G62 VanDerWaalsContact O-N 3.09Å; T60-G62 VanDerWaalsContact C-N 3.34Å; T60-G62 PolarHBondContact O-N 3.42Å; G62-L64 PolarHBondContact O-N 2.87Å; G62-L65 WeakPolarHBondContact O-CB 3.11Å; G62-L65 PolarHBondContact O-N 3.09Å; G62-V66 WeakPolarHBondContact O-CG2 3.17Å; G62-V66 PolarHBondContact O-N 3.37Å
63	E	69.1	Low	71.4	Confident	39 Å²	39	60.2 Å²	60.2	18%	0.182	33%	0.327	C	S	.	.	H	α-helix	trans	-60.9	-43.6	178.4	-81.8	177.6	-177.4	0	0	112	I59 T60 L65 V66 S67 M283 R355	I59-E63 HydrophobicContact CG2-CG 4.18Å; I59-E63 VanDerWaalsContact CG2-OE1 3.24Å; I59-E63 WeakPolarHBondContact CG2-OE1 3.35Å; I59-E63 WeakPolarHBondContact O-CB 3.46Å; I59-E63 WeakPolarHBondContact O-CG 3.39Å; I59-E63 PolarHBondContact O-N 3.16Å; T60-E63 PolarHBondContact O-N 2.81Å; E63-L65 VanDerWaalsContact C-N 3.29Å; E63-L65 PolarHBondContact O-N 3.39Å; E63-V66 PolarHBondContact O-N 3.06Å; E63-S67 PolarHBondContact O-N 2.84Å; E63-S67 VanDerWaalsContact O-N 3.13Å; E63-M283 VanDerWaalsContact C-CE 3.44Å; E63-M283 HydrophobicContact CB-CE 3.49Å; E63-M283 VanDerWaalsContact CB-CE 3.49Å; E63-M283 HydrophobicContact CG-CE 4.13Å; E63-M283 WeakPolarHBondContact O-CE 3.4Å; E63-R355 WeakPolarHBondContact OE1-CD 3.32Å; E63-R355 IonicContact OE1-CZ 3.69Å; E63-R355 IonicContact OE1-NE 2.94Å; E63-R355 IonicContact OE1-NH1 2.9Å; E63-R355 PolarHBondContact OE1-NH1 2.99Å
64	L	81.7	Confident	73.6	Confident	51 Å²	51	58.5 Å²	58.5	27%	0.267	31%	0.308	S	S	.	.	H	α-helix	trans	-63.8	-33.7	173.6	-88.8	77.6	0	0	0	112.3	T60 G62 K68 L284	T60-L64 WeakPolarHBondContact O-CD1 3.15Å; T60-L64 PolarHBondContact O-N 3.28Å; T60-L64 VanDerWaalsContact O-N 3.09Å; G62-L64 PolarHBondContact O-N 2.87Å; L64-K68 WeakPolarHBondContact O-CG 3.47Å; L64-K68 PolarHBondContact O-N 3.33Å; L64-L284 HydrophobicContact CD2-CD2 4.02Å; L64-L284 HydrophobicContact CG-CD2 4.36Å
65	L	88.4	Confident	75.7	Confident	96 Å²	96	57.2 Å²	57.2	50%	0.503	29%	0.291	S	S	.	.	H	α-helix	trans	-67.3	-41	175.1	179.9	64.5	0	0	0	111.6	K61 G62 E63 S67 K68 L69	K61-L65 PolarHBondContact O-N 3.42Å; G62-L65 WeakPolarHBondContact O-CB 3.11Å; G62-L65 PolarHBondContact O-N 3.09Å; E63-L65 VanDerWaalsContact C-N 3.29Å; E63-L65 PolarHBondContact O-N 3.39Å; L65-S67 VanDerWaalsContact C-N 3.32Å; L65-S67 PolarHBondContact O-N 2.87Å; L65-K68 WeakPolarHBondContact O-CB 3.38Å; L65-K68 PolarHBondContact O-N 3.3Å; L65-L69 HydrophobicContact CD1-CD1 4.36Å; L65-L69 HydrophobicContact CD1-CG 4.27Å; L65-L69 HydrophobicContact CG-CD1 4.08Å; L65-L69 HydrophobicContact CG-CG 4.4Å; L65-L69 WeakPolarHBondContact O-CG 3.28Å; L65-L69 PolarHBondContact O-N 3.24Å
66	V	90.4	Very high	78.2	Confident	28 Å²	28	48.6 Å²	48.6	17%	0.17	26%	0.258	C	S	.	.	H	α-helix	trans	-58.5	-44.9	175.9	176.2	0	0	0	0	110.6	G62 E63 L69 F70 M350 Q353 F354	G62-V66 WeakPolarHBondContact O-CG2 3.17Å; G62-V66 PolarHBondContact O-N 3.37Å; E63-V66 PolarHBondContact O-N 3.06Å; V66-L69 PolarHBondContact O-N 3.16Å; V66-F70 WeakPolarHBondContact O-CB 3.45Å; V66-F70 PolarHBondContact O-N 3.28Å; V66-M350 HydrophobicContact CG1-CB 4.47Å; V66-M350 WeakPolarHBondContact CG1-O 3.35Å; V66-Q353 HydrophobicContact CG1-CB 3.68Å; V66-Q353 HydrophobicContact CG2-CB 4.15Å; V66-F354 HydrophobicContact CG1-CD1 3.78Å; V66-F354 HydrophobicContact CG1-CE1 3.77Å
67	S	88.9	Confident	80.7	Confident	2 Å²	2	42.6 Å²	42.6	1%	0.014	23%	0.231	C	C	.	.	H	α-helix	trans	-60.1	-45.7	176	176	0	0	0	0	112.4	E63 L65 L69 F70 Y71 T280	E63-S67 PolarHBondContact O-N 2.84Å; E63-S67 VanDerWaalsContact O-N 3.13Å; L65-S67 VanDerWaalsContact C-N 3.32Å; L65-S67 PolarHBondContact O-N 2.87Å; S67-L69 PolarHBondContact O-N 2.97Å; S67-F70 WeakPolarHBondContact O-CB 3.47Å; S67-F70 PolarHBondContact O-N 2.81Å; S67-Y71 WeakPolarHBondContact O-CD2 3.49Å; S67-Y71 PolarHBondContact O-N 2.78Å; S67-Y71 WeakPolarHBondContact OG-CE2 3.14Å; S67-T280 WeakPolarHBondContact OG-CG2 3.5Å; S67-T280 PolarHBondContact OG-OG1 3.22Å
68	K	91.3	Very high	82.9	Confident	55 Å²	55	41.1 Å²	41.1	24%	0.239	22%	0.217	C	C	.	.	H	α-helix	trans	-57.6	-47.7	175.3	-67.9	173.5	176.9	-178.5	0	112.5	L64 L65 Y71 F72 Y297	L64-K68 WeakPolarHBondContact O-CG 3.47Å; L64-K68 PolarHBondContact O-N 3.33Å; L65-K68 WeakPolarHBondContact O-CB 3.38Å; L65-K68 PolarHBondContact O-N 3.3Å; K68-Y71 PolarHBondContact O-N 3.28Å; K68-F72 WeakPolarHBondContact O-CB 3.24Å; K68-F72 PolarHBondContact O-N 2.97Å; K68-Y297 HydrophobicContact CB-CD1 4.12Å; K68-Y297 HydrophobicContact CB-CD2 4.02Å; K68-Y297 HydrophobicContact CB-CE1 4.39Å; K68-Y297 HydrophobicContact CB-CE2 4.3Å; K68-Y297 HydrophobicContact CB-CG 3.92Å; K68-Y297 HydrophobicContact CD-CD2 4.04Å; K68-Y297 HydrophobicContact CD-CE1 4.43Å; K68-Y297 HydrophobicContact CD-CE2 3.56Å; K68-Y297 HydrophobicContact CG-CD2 3.78Å; K68-Y297 HydrophobicContact CG-CE2 3.85Å; K68-Y297 HydrophobicContact CG-CG 4.21Å; K68-Y297 WeakPolarHBondContact O-CB 3.46Å
69	L	94.1	Very high	85.3	Confident	61 Å²	61	37.1 Å²	37.1	32%	0.319	19%	0.189	S	C	.	.	H	α-helix	trans	-66.9	-39.4	-179.4	-69.3	176.1	0	0	0	111.4	L65 V66 S67 F72 F73 M350	L65-L69 HydrophobicContact CD1-CD1 4.36Å; L65-L69 HydrophobicContact CD1-CG 4.27Å; L65-L69 HydrophobicContact CG-CD1 4.08Å; L65-L69 HydrophobicContact CG-CG 4.4Å; L65-L69 WeakPolarHBondContact O-CG 3.28Å; L65-L69 PolarHBondContact O-N 3.24Å; V66-L69 PolarHBondContact O-N 3.16Å; S67-L69 PolarHBondContact O-N 2.97Å; L69-F72 PolarHBondContact O-N 3.49Å; L69-F73 HydrophobicContact CB-CD2 4.42Å; L69-F73 HydrophobicContact CB-CE2 4.33Å; L69-F73 HydrophobicContact CD2-CE2 4.47Å; L69-F73 WeakPolarHBondContact O-CD2 3.31Å; L69-F73 PolarHBondContact O-N 3.06Å; L69-M350 HydrophobicContact CB-CG 4.03Å; L69-M350 HydrophobicContact CB-SD 3.84Å; L69-M350 HydrophobicContact CD1-SD 4.04Å
70	F	95.1	Very high	87.5	Confident	0 Å²	0	34.6 Å²	34.6	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-56	-54.1	172.2	172.1	-92.8	0	0	0	110.9	V66 S67 F72 F73 F74 L135 A276 A347 M350 A351 F354	V66-F70 WeakPolarHBondContact O-CB 3.45Å; V66-F70 PolarHBondContact O-N 3.28Å; S67-F70 WeakPolarHBondContact O-CB 3.47Å; S67-F70 PolarHBondContact O-N 2.81Å; F70-F72 VanDerWaalsContact C-N 3.31Å; F70-F72 PolarHBondContact O-N 2.97Å; F70-F73 PolarHBondContact O-N 2.75Å; F70-F74 HydrophobicContact CE1-CB 4.23Å; F70-F74 HydrophobicContact CE1-CG 4.33Å; F70-F74 HydrophobicContact CE2-CD2 4.36Å; F70-F74 HydrophobicContact CZ-CB 4.19Å; F70-F74 AromaticContact CZ-CD2 3.85Å; F70-F74 HydrophobicContact CZ-CD2 3.85Å; F70-F74 HydrophobicContact CZ-CE2 4.48Å; F70-F74 HydrophobicContact CZ-CG 4.11Å; F70-F74 WeakPolarHBondContact O-CB 3.47Å; F70-F74 PolarHBondContact O-N 3.43Å; F70-L135 HydrophobicContact CE2-CD1 4.05Å; F70-L135 HydrophobicContact CE2-CD2 4.45Å; F70-A276 HydrophobicContact CD1-CB 4.02Å; F70-A276 HydrophobicContact CE1-CB 3.22Å; F70-A276 HydrophobicContact CZ-CB 3.61Å; F70-A347 HydrophobicContact CD2-CB 4.36Å; F70-A347 WeakPolarHBondContact CD2-O 3.3Å; F70-A347 HydrophobicContact CE2-CB 4.35Å; F70-M350 HydrophobicContact CB-CB 3.94Å; F70-M350 HydrophobicContact CD2-CB 4.46Å; F70-A351 HydrophobicContact CD2-CB 4.03Å; F70-A351 HydrophobicContact CE2-CB 3.96Å; F70-F354 HydrophobicContact CB-CE1 4.08Å; F70-F354 HydrophobicContact CB-CZ 3.65Å; F70-F354 HydrophobicContact CD1-CE2 4.14Å; F70-F354 AromaticContact CD1-CZ 3.83Å; F70-F354 HydrophobicContact CD1-CZ 3.83Å; F70-F354 HydrophobicContact CD2-CE2 4.34Å; F70-F354 HydrophobicContact CD2-CZ 4.21Å; F70-F354 HydrophobicContact CG-CE1 4.43Å; F70-F354 HydrophobicContact CG-CE2 4.06Å; F70-F354 AromaticContact CG-CZ 3.6Å; F70-F354 HydrophobicContact CG-CZ 3.6Å
71	Y	91.9	Very high	89.4	Confident	0 Å²	0	32.2 Å²	32.2	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-60.6	-41.7	179.5	-78.5	-61.6	0	0	0	112.2	S67 K68 Y75 I273 D277 T280 Y291 Q294 G298	S67-Y71 WeakPolarHBondContact O-CD2 3.49Å; S67-Y71 PolarHBondContact O-N 2.78Å; S67-Y71 WeakPolarHBondContact OG-CE2 3.14Å; K68-Y71 PolarHBondContact O-N 3.28Å; Y71-Y75 HydrophobicContact CD1-CD2 4.19Å; Y71-Y75 AromaticContact CD1-CE2 3.83Å; Y71-Y75 HydrophobicContact CD1-CE2 3.83Å; Y71-Y75 HydrophobicContact CE1-CE2 4.41Å; Y71-Y75 WeakPolarHBondContact O-CB 3Å; Y71-Y75 WeakPolarHBondContact O-CD2 3.3Å; Y71-Y75 PolarHBondContact O-N 2.92Å; Y71-I273 HydrophobicContact CD1-CD1 4.47Å; Y71-I273 HydrophobicContact CE1-CD1 3.92Å; Y71-D277 VanDerWaalsContact CE1-OD1 3.26Å; Y71-D277 WeakPolarHBondContact CE1-OD1 3.3Å; Y71-D277 VanDerWaalsContact OH-CA 3.28Å; Y71-D277 WeakPolarHBondContact OH-CA 3.42Å; Y71-D277 PolarHBondContact OH-OD1 3.31Å; Y71-T280 HydrophobicContact CE2-CG2 4.05Å; Y71-T280 WeakPolarHBondContact CE2-OG1 3.36Å; Y71-T280 PolarHBondContact OH-OG1 3.47Å; Y71-Y291 WeakPolarHBondContact OH-CE2 3.32Å; Y71-Y291 PolarHBondContact OH-OH 3.49Å; Y71-Q294 HydrophobicContact CD2-CB 4.25Å; Y71-Q294 HydrophobicContact CE2-CB 4.21Å; Y71-G298 WeakPolarHBondContact O-CA 3.45Å
72	F	95.1	Very high	90.8	Very high	45 Å²	45	25.2 Å²	25.2	20%	0.197	13%	0.131	C	C	.	.	H	α-helix	trans	-57.2	-55.6	176	179.1	-91.2	0	0	0	111.5	K68 L69 F70 A76 Y297 L300 L304	K68-F72 WeakPolarHBondContact O-CB 3.24Å; K68-F72 PolarHBondContact O-N 2.97Å; L69-F72 PolarHBondContact O-N 3.49Å; F70-F72 VanDerWaalsContact C-N 3.31Å; F70-F72 PolarHBondContact O-N 2.97Å; F72-A76 WeakPolarHBondContact O-CB 3.42Å; F72-A76 PolarHBondContact O-N 2.95Å; F72-Y297 WeakPolarHBondContact CA-O 3.48Å; F72-L300 HydrophobicContact CD2-CD2 4.36Å; F72-L300 HydrophobicContact CD2-CG 4.39Å; F72-L300 HydrophobicContact CE2-CD2 4.25Å; F72-L300 HydrophobicContact CE2-CG 4.13Å; F72-L304 HydrophobicContact CE2-CD2 4.44Å; F72-L304 HydrophobicContact CZ-CD2 4.08Å
73	F	97.3	Very high	92	Very high	47 Å²	47	24.1 Å²	24.1	21%	0.206	12%	0.118	C	C	.	.	H	α-helix	trans	-68.7	-39.9	-177.4	-72.1	-58.2	0	0	0	112.9	L69 F70 A76 A77 L343 C346 A347 M350	L69-F73 HydrophobicContact CB-CD2 4.42Å; L69-F73 HydrophobicContact CB-CE2 4.33Å; L69-F73 HydrophobicContact CD2-CE2 4.47Å; L69-F73 WeakPolarHBondContact O-CD2 3.31Å; L69-F73 PolarHBondContact O-N 3.06Å; F70-F73 PolarHBondContact O-N 2.75Å; F73-A76 PolarHBondContact O-N 2.9Å; F73-A77 PolarHBondContact O-N 3.42Å; F73-L343 HydrophobicContact CD1-CD2 4.07Å; F73-C346 HydrophobicContact CB-CB 4.16Å; F73-C346 HydrophobicContact CD1-CB 3.71Å; F73-C346 HydrophobicContact CD2-CB 3.94Å; F73-C346 HydrophobicContact CE1-CB 4.04Å; F73-C346 HydrophobicContact CE2-CB 4.25Å; F73-C346 HydrophobicContact CG-CB 3.67Å; F73-C346 HydrophobicContact CZ-CB 4.3Å; F73-A347 HydrophobicContact CB-CB 3.9Å; F73-M350 HydrophobicContact CD2-CG 4.03Å; F73-M350 HydrophobicContact CE2-CG 4.41Å
74	F	96.5	Very high	93.2	Very high	4 Å²	4	22.2 Å²	22.2	2%	0.018	11%	0.109	C	C	.	.	H	α-helix	trans	-60	-53.3	178.6	-176.5	-94.1	0	0	0	110.6	F70 A77 F78 L135 A272 I273 M344 A347	F70-F74 HydrophobicContact CE1-CB 4.23Å; F70-F74 HydrophobicContact CE1-CG 4.33Å; F70-F74 HydrophobicContact CE2-CD2 4.36Å; F70-F74 HydrophobicContact CZ-CB 4.19Å; F70-F74 AromaticContact CZ-CD2 3.85Å; F70-F74 HydrophobicContact CZ-CD2 3.85Å; F70-F74 HydrophobicContact CZ-CE2 4.48Å; F70-F74 HydrophobicContact CZ-CG 4.11Å; F70-F74 WeakPolarHBondContact O-CB 3.47Å; F70-F74 PolarHBondContact O-N 3.43Å; F74-A77 WeakPolarHBondContact O-CB 3.34Å; F74-A77 PolarHBondContact O-N 3.18Å; F74-F78 HydrophobicContact CD1-CD2 4.1Å; F74-F78 HydrophobicContact CD1-CE2 4.04Å; F74-F78 AromaticContact CE1-CD2 3.87Å; F74-F78 HydrophobicContact CE1-CD2 3.87Å; F74-F78 AromaticContact CE1-CE2 3.41Å; F74-F78 HydrophobicContact CE1-CE2 3.41Å; F74-F78 VanDerWaalsContact CE1-CE2 3.41Å; F74-F78 HydrophobicContact CE1-CZ 4.31Å; F74-F78 AromaticContact CE2-CE2 3.99Å; F74-F78 HydrophobicContact CE2-CE2 3.99Å; F74-F78 HydrophobicContact CZ-CD2 4.27Å; F74-F78 AromaticContact CZ-CE2 3.4Å; F74-F78 HydrophobicContact CZ-CE2 3.4Å; F74-F78 HydrophobicContact CZ-CZ 4.13Å; F74-F78 WeakPolarHBondContact O-CD2 3.48Å; F74-F78 PolarHBondContact O-N 2.76Å; F74-L135 HydrophobicContact CD2-CD2 3.82Å; F74-L135 HydrophobicContact CE2-CD2 3.73Å; F74-A272 HydrophobicContact CE2-CB 4.04Å; F74-A272 HydrophobicContact CZ-CB 4.35Å; F74-I273 HydrophobicContact CD1-CD1 4.24Å; F74-I273 HydrophobicContact CE1-CB 4.24Å; F74-I273 HydrophobicContact CE1-CD1 3.89Å; F74-I273 HydrophobicContact CE1-CG1 4.43Å; F74-I273 HydrophobicContact CZ-CB 4.21Å; F74-M344 HydrophobicContact CD2-CE 3.87Å; F74-M344 HydrophobicContact CD2-SD 3.81Å; F74-M344 HydrophobicContact CE2-CE 3.97Å; F74-M344 HydrophobicContact CE2-SD 4.16Å; F74-A347 HydrophobicContact CB-CB 4.11Å
75	Y	94	Very high	93.8	Very high	32 Å²	32	20 Å²	20	13%	0.125	10%	0.097	C	C	.	.	H	α-helix	trans	-75.6	-24.2	179.2	-75.5	-72.4	0	0	0	113.7	Y71 A77 F78 G79 I273 R295 G298 W302	Y71-Y75 HydrophobicContact CD1-CD2 4.19Å; Y71-Y75 AromaticContact CD1-CE2 3.83Å; Y71-Y75 HydrophobicContact CD1-CE2 3.83Å; Y71-Y75 HydrophobicContact CE1-CE2 4.41Å; Y71-Y75 WeakPolarHBondContact O-CB 3Å; Y71-Y75 WeakPolarHBondContact O-CD2 3.3Å; Y71-Y75 PolarHBondContact O-N 2.92Å; Y75-A77 VanDerWaalsContact C-N 3.34Å; Y75-F78 PolarHBondContact O-N 2.99Å; Y75-G79 PolarHBondContact O-N 2.75Å; Y75-I273 HydrophobicContact CE2-CD1 3.87Å; Y75-I273 WeakPolarHBondContact OH-CD1 3.07Å; Y75-I273 WeakPolarHBondContact OH-CG1 3.46Å; Y75-R295 VanDerWaalsContact CE1-NH2 3.32Å; Y75-R295 VanDerWaalsContact CE2-NE 3.35Å; Y75-R295 PolarHBondContact OH-NE 2.95Å; Y75-R295 PolarHBondContact OH-NH2 3.48Å; Y75-G298 WeakPolarHBondContact CB-O 3.26Å; Y75-W302 AromaticContact CD1-CE3 3.97Å; Y75-W302 HydrophobicContact CD1-CE3 3.97Å; Y75-W302 HydrophobicContact CD1-CZ3 4.3Å; Y75-W302 WeakPolarHBondContact O-CA 3.18Å
76	A	96.9	Very high	94.1	Very high	2 Å²	2	15.6 Å²	15.6	2%	0.017	8%	0.075	C	C	.	.	H	α-helix	trans	-63.2	-40.8	167.4	0	0	0	0	0	111.5	F72 F73 G79 S80 G301 S305 L343	F72-A76 WeakPolarHBondContact O-CB 3.42Å; F72-A76 PolarHBondContact O-N 2.95Å; F73-A76 PolarHBondContact O-N 2.9Å; A76-G79 PolarHBondContact O-N 3.5Å; A76-S80 PolarHBondContact O-N 2.83Å; A76-G301 WeakPolarHBondContact CA-O 3.39Å; A76-G301 WeakPolarHBondContact CB-O 3.36Å; A76-S305 WeakPolarHBondContact O-CB 3.45Å; A76-S305 PolarHBondContact O-OG 3.48Å; A76-L343 HydrophobicContact CB-CD1 4.05Å; A76-L343 HydrophobicContact CB-CD2 4.22Å
77	A	97.5	Very high	94.3	Very high	0 Å²	0	14.3 Å²	14.3	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-58.3	-51.8	172.3	0	0	0	0	0	109.5	F73 F74 Y75 G79 S80 F340 L343 M344	F73-A77 PolarHBondContact O-N 3.42Å; F74-A77 WeakPolarHBondContact O-CB 3.34Å; F74-A77 PolarHBondContact O-N 3.18Å; Y75-A77 VanDerWaalsContact C-N 3.34Å; A77-G79 VanDerWaalsContact C-N 3.34Å; A77-G79 PolarHBondContact O-N 2.72Å; A77-S80 WeakPolarHBondContact O-CB 3.18Å; A77-S80 PolarHBondContact O-N 2.67Å; A77-S80 VanDerWaalsContact O-N 3.08Å; A77-S80 PolarHBondContact O-OG 3.36Å; A77-F340 VanDerWaalsContact C-CD2 3.45Å; A77-F340 HydrophobicContact CB-CD2 3.94Å; A77-F340 HydrophobicContact CB-CE2 3.96Å; A77-F340 HydrophobicContact CB-CG 4.34Å; A77-F340 HydrophobicContact CB-CZ 4.46Å; A77-F340 WeakPolarHBondContact O-CD2 3.17Å; A77-L343 HydrophobicContact CB-CB 3.77Å; A77-M344 HydrophobicContact CB-CB 4.03Å; A77-M344 HydrophobicContact CB-CE 3.83Å
78	F	94.2	Very high	94.6	Very high	27 Å²	27	14.4 Å²	14.4	12%	0.118	7%	0.067	C	C	.	.	H	α-helix	trans	-56.8	-46.2	177.3	-82.9	-92.8	0	0	0	113.2	F74 Y75 S80 L81 F82 P83 W138 W302 M344	F74-F78 HydrophobicContact CD1-CD2 4.1Å; F74-F78 HydrophobicContact CD1-CE2 4.04Å; F74-F78 AromaticContact CE1-CD2 3.87Å; F74-F78 HydrophobicContact CE1-CD2 3.87Å; F74-F78 AromaticContact CE1-CE2 3.41Å; F74-F78 HydrophobicContact CE1-CE2 3.41Å; F74-F78 VanDerWaalsContact CE1-CE2 3.41Å; F74-F78 HydrophobicContact CE1-CZ 4.31Å; F74-F78 AromaticContact CE2-CE2 3.99Å; F74-F78 HydrophobicContact CE2-CE2 3.99Å; F74-F78 HydrophobicContact CZ-CD2 4.27Å; F74-F78 AromaticContact CZ-CE2 3.4Å; F74-F78 HydrophobicContact CZ-CE2 3.4Å; F74-F78 HydrophobicContact CZ-CZ 4.13Å; F74-F78 WeakPolarHBondContact O-CD2 3.48Å; F74-F78 PolarHBondContact O-N 2.76Å; Y75-F78 PolarHBondContact O-N 2.99Å; F78-S80 PolarHBondContact O-N 3.46Å; F78-L81 PolarHBondContact O-N 2.91Å; F78-F82 HydrophobicContact CB-CD2 4.19Å; F78-F82 HydrophobicContact CD1-CB 4.47Å; F78-F82 AromaticContact CD1-CD2 3.28Å; F78-F82 HydrophobicContact CD1-CD2 3.28Å; F78-F82 AromaticContact CD1-CE2 3.59Å; F78-F82 HydrophobicContact CD1-CE2 3.59Å; F78-F82 AromaticContact CD1-CG 3.83Å; F78-F82 HydrophobicContact CD1-CG 3.83Å; F78-F82 HydrophobicContact CD1-CZ 4.45Å; F78-F82 AromaticContact CE1-CD2 3.89Å; F78-F82 HydrophobicContact CE1-CD2 3.89Å; F78-F82 AromaticContact CE1-CE2 3.71Å; F78-F82 HydrophobicContact CE1-CE2 3.71Å; F78-F82 HydrophobicContact CE1-CG 4.46Å; F78-F82 HydrophobicContact CE1-CZ 4.25Å; F78-F82 AromaticContact CG-CD2 3.99Å; F78-F82 HydrophobicContact CG-CD2 3.99Å; F78-F82 HydrophobicContact CG-CE2 4.38Å; F78-F82 WeakPolarHBondContact O-CB 3.37Å; F78-F82 PolarHBondContact O-N 3.41Å; F78-P83 WeakPolarHBondContact O-CD 3.28Å; F78-W138 AromaticContact CE1-CH2 3.8Å; F78-W138 HydrophobicContact CE1-CH2 3.8Å; F78-W138 HydrophobicContact CE1-CZ2 4.18Å; F78-W138 HydrophobicContact CE1-CZ3 4.15Å; F78-W138 HydrophobicContact CZ-CD2 4.29Å; F78-W138 AromaticContact CZ-CE2 3.83Å; F78-W138 HydrophobicContact CZ-CE3 4.34Å; F78-W138 AromaticContact CZ-CH2 3.57Å; F78-W138 HydrophobicContact CZ-CH2 3.57Å; F78-W138 AromaticContact CZ-CZ2 3.51Å; F78-W138 HydrophobicContact CZ-CZ2 3.51Å; F78-W138 AromaticContact CZ-CZ3 3.99Å; F78-W138 HydrophobicContact CZ-CZ3 3.99Å; F78-W302 HydrophobicContact CB-CE3 3.7Å; F78-W302 HydrophobicContact CB-CH2 4.1Å; F78-W302 HydrophobicContact CB-CZ3 3.38Å; F78-W302 HydrophobicContact CD1-CZ3 4.47Å; F78-W302 HydrophobicContact CG-CZ3 4.2Å; F78-M344 HydrophobicContact CD2-CE 4.36Å; F78-M344 HydrophobicContact CE2-CE 4.01Å
79	G	93.4	Very high	94.8	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	6%	0.056	C	C	.	.	H	α-helix	trans	-60.1	-27.8	178.4	0	0	0	0	0	114.1	Y75 A76 A77 L81 M306	Y75-G79 PolarHBondContact O-N 2.75Å; A76-G79 PolarHBondContact O-N 3.5Å; A77-G79 VanDerWaalsContact C-N 3.34Å; A77-G79 PolarHBondContact O-N 2.72Å; G79-L81 PolarHBondContact O-N 3.19Å; G79-M306 WeakPolarHBondContact O-CA 3.35Å; G79-M306 WeakPolarHBondContact O-CB 3.47Å
80	S	96	Very high	94.9	Very high	0 Å²	0	9 Å²	9	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-72.7	-22	-179.6	68.7	0	0	0	0	114.9	A76 A77 F78 S305 C336 F340	A76-S80 PolarHBondContact O-N 2.83Å; A77-S80 WeakPolarHBondContact O-CB 3.18Å; A77-S80 PolarHBondContact O-N 2.67Å; A77-S80 VanDerWaalsContact O-N 3.08Å; A77-S80 PolarHBondContact O-OG 3.36Å; F78-S80 PolarHBondContact O-N 3.46Å; S80-S305 WeakPolarHBondContact CB-OG 3.31Å; S80-S305 PolarHBondContact N-OG 3.2Å; S80-C336 WeakPolarHBondContact O-CB 3.21Å; S80-F340 VanDerWaalsContact OG-CA 3.31Å; S80-F340 WeakPolarHBondContact OG-CA 3.28Å; S80-F340 PolarHBondContact OG-N 3.28Å
81	L	95	Very high	94.7	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-131.2	-48.9	-169.9	176.3	63.3	0	0	0	112.9	F78 G79 L84 I85 T142 C336 F337 F340	F78-L81 PolarHBondContact O-N 2.91Å; G79-L81 PolarHBondContact O-N 3.19Å; L81-L84 CarbonylContact O-C 3.07Å; L81-L84 WeakPolarHBondContact O-CA 3.38Å; L81-L84 PolarHBondContact O-N 3.04Å; L81-I85 PolarHBondContact O-N 3.41Å; L81-T142 HydrophobicContact CD2-CG2 3.4Å; L81-T142 VanDerWaalsContact CD2-CG2 3.4Å; L81-C336 HydrophobicContact CB-CB 4.48Å; L81-C336 HydrophobicContact CD1-CB 3.77Å; L81-F337 HydrophobicContact CD1-CD1 4.07Å; L81-F337 HydrophobicContact CD1-CD2 4.33Å; L81-F337 HydrophobicContact CD1-CE1 3.87Å; L81-F337 HydrophobicContact CD1-CE2 4.13Å; L81-F337 HydrophobicContact CD1-CG 4.28Å; L81-F337 HydrophobicContact CD1-CZ 3.89Å; L81-F337 HydrophobicContact CD2-CD1 3.78Å; L81-F337 HydrophobicContact CD2-CE1 3.77Å; L81-F337 HydrophobicContact CG-CE1 4.46Å; L81-F340 HydrophobicContact CB-CB 4.22Å; L81-F340 HydrophobicContact CB-CD2 4.06Å; L81-F340 HydrophobicContact CB-CG 4.49Å; L81-F340 HydrophobicContact CD2-CB 4.27Å; L81-F340 HydrophobicContact CD2-CD2 4.14Å; L81-F340 HydrophobicContact CD2-CG 4.19Å
82	F	92.5	Very high	94.8	Very high	6 Å²	6	10.3 Å²	10.3	3%	0.026	5%	0.047	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.1	-36.4	-167	-84.6	-75.5	0	0	0	115.8	F78 L84 I85 R106 W138 W302 F340 F433	F78-F82 HydrophobicContact CB-CD2 4.19Å; F78-F82 HydrophobicContact CD1-CB 4.47Å; F78-F82 AromaticContact CD1-CD2 3.28Å; F78-F82 HydrophobicContact CD1-CD2 3.28Å; F78-F82 AromaticContact CD1-CE2 3.59Å; F78-F82 HydrophobicContact CD1-CE2 3.59Å; F78-F82 AromaticContact CD1-CG 3.83Å; F78-F82 HydrophobicContact CD1-CG 3.83Å; F78-F82 HydrophobicContact CD1-CZ 4.45Å; F78-F82 AromaticContact CE1-CD2 3.89Å; F78-F82 HydrophobicContact CE1-CD2 3.89Å; F78-F82 AromaticContact CE1-CE2 3.71Å; F78-F82 HydrophobicContact CE1-CE2 3.71Å; F78-F82 HydrophobicContact CE1-CG 4.46Å; F78-F82 HydrophobicContact CE1-CZ 4.25Å; F78-F82 AromaticContact CG-CD2 3.99Å; F78-F82 HydrophobicContact CG-CD2 3.99Å; F78-F82 HydrophobicContact CG-CE2 4.38Å; F78-F82 WeakPolarHBondContact O-CB 3.37Å; F78-F82 PolarHBondContact O-N 3.41Å; F82-L84 PolarHBondContact O-N 3.41Å; F82-I85 HydrophobicContact CD1-CD1 4.46Å; F82-I85 HydrophobicContact CE1-CD1 4.04Å; F82-I85 VanDerWaalsContact O-CG2 3.32Å; F82-I85 WeakPolarHBondContact O-CG2 3.22Å; F82-R106 VanDerWaalsContact CE1-NE 3.32Å; F82-R106 VanDerWaalsContact CZ-CZ 3.41Å; F82-W138 HydrophobicContact CE2-CZ3 4.18Å; F82-W138 AromaticContact CZ-CZ3 3.84Å; F82-W138 HydrophobicContact CZ-CZ3 3.84Å; F82-W302 HydrophobicContact CB-CH2 4.48Å; F82-F340 HydrophobicContact CD2-CD2 4.46Å; F82-F340 HydrophobicContact CD2-CE2 4.05Å; F82-F340 HydrophobicContact CE2-CD2 4.19Å; F82-F340 AromaticContact CE2-CE2 3.55Å; F82-F340 HydrophobicContact CE2-CE2 3.55Å; F82-F340 HydrophobicContact CE2-CZ 4.17Å; F82-F433 HydrophobicContact CB-CZ 4.07Å
83	P	92.3	Very high	94.7	Very high	11 Å²	11	8.2 Å²	8.2	7%	0.071	4%	0.038	C	C	.	.	T	Hydrogen-bonded Turn	trans	-61.7	-26.1	171.5	-21.7	32.3	0	0	0	113.3	F78 W302 M306 F437	F78-P83 WeakPolarHBondContact O-CD 3.28Å; P83-W302 HydrophobicContact CG-CZ2 3.74Å; P83-M306 HydrophobicContact CB-CE 4.23Å; P83-M306 HydrophobicContact CB-CG 4.48Å; P83-M306 HydrophobicContact CB-SD 3.73Å; P83-M306 HydrophobicContact CG-CG 4.23Å; P83-M306 HydrophobicContact CG-SD 3.76Å; P83-F437 HydrophobicContact CB-CD2 4.27Å; P83-F437 HydrophobicContact CB-CE2 3.65Å; P83-F437 VanDerWaalsContact O-CD2 3.24Å; P83-F437 WeakPolarHBondContact O-CD2 3.37Å
84	L	94.6	Very high	94.6	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.028	C	C	.	.	T	Hydrogen-bonded Turn	trans	-102.5	-12.4	-172.7	-67	170.9	0	0	0	113.8	L81 F82 S86 I87 Y88 M306 I309 L313 Y333 F437 Y450	L81-L84 CarbonylContact O-C 3.07Å; L81-L84 WeakPolarHBondContact O-CA 3.38Å; L81-L84 PolarHBondContact O-N 3.04Å; F82-L84 PolarHBondContact O-N 3.41Å; L84-S86 PolarHBondContact O-N 3.22Å; L84-S86 VanDerWaalsContact O-N 3.14Å; L84-I87 HydrophobicContact CD2-CD1 4Å; L84-I87 WeakPolarHBondContact O-CA 3.41Å; L84-I87 WeakPolarHBondContact O-CB 3.42Å; L84-I87 PolarHBondContact O-N 2.96Å; L84-Y88 PolarHBondContact O-N 3.08Å; L84-M306 HydrophobicContact CD1-CE 3.94Å; L84-M306 HydrophobicContact CD1-SD 4.06Å; L84-M306 HydrophobicContact CD2-CE 3.8Å; L84-M306 HydrophobicContact CG-CE 3.75Å; L84-M306 HydrophobicContact CG-SD 4.08Å; L84-I309 HydrophobicContact CD1-CG2 3.88Å; L84-L313 HydrophobicContact CD1-CD1 3.5Å; L84-Y333 HydrophobicContact CB-CD1 4.47Å; L84-Y333 HydrophobicContact CB-CE1 4.01Å; L84-Y333 HydrophobicContact CD1-CE1 4.41Å; L84-Y333 HydrophobicContact CD2-CE1 4.49Å; L84-F437 HydrophobicContact CD2-CD2 4.28Å; L84-Y450 HydrophobicContact CD2-CD2 3.77Å; L84-Y450 HydrophobicContact CD2-CE2 4.5Å
85	I	94.6	Very high	94.6	Very high	3 Å²	3	7.7 Å²	7.7	2%	0.015	4%	0.037	C	C	.	.	H	α-helix	trans	-58	-34.1	-172	-159.1	168.8	0	0	0	113.3	L81 F82 Y88 F89 V103	L81-I85 PolarHBondContact O-N 3.41Å; F82-I85 HydrophobicContact CD1-CD1 4.46Å; F82-I85 HydrophobicContact CE1-CD1 4.04Å; F82-I85 VanDerWaalsContact O-CG2 3.32Å; F82-I85 WeakPolarHBondContact O-CG2 3.22Å; I85-Y88 WeakPolarHBondContact O-CB 3.23Å; I85-Y88 PolarHBondContact O-N 3.5Å; I85-F89 HydrophobicContact CD1-CE2 4.34Å; I85-F89 HydrophobicContact CD1-CZ 3.93Å; I85-F89 HydrophobicContact CG1-CE1 4.24Å; I85-F89 HydrophobicContact CG1-CE2 3.85Å; I85-F89 HydrophobicContact CG1-CZ 3.65Å; I85-F89 WeakPolarHBondContact O-CD2 3.11Å; I85-F89 WeakPolarHBondContact O-CG 3.38Å; I85-F89 PolarHBondContact O-N 3.44Å; I85-V103 HydrophobicContact CG2-CG2 3.92Å
86	S	95.3	Very high	94.7	Very high	4 Å²	4	6.1 Å²	6.1	3%	0.028	3%	0.032	C	C	.	.	H	α-helix	trans	-67	-39.2	176.4	-172	0	0	0	0	111.8	L84 Y88 F89 K90 C434 W438	L84-S86 PolarHBondContact O-N 3.22Å; L84-S86 VanDerWaalsContact O-N 3.14Å; S86-Y88 VanDerWaalsContact C-N 3.34Å; S86-F89 PolarHBondContact O-N 2.84Å; S86-K90 PolarHBondContact O-N 2.67Å; S86-C434 WeakPolarHBondContact CB-O 3.24Å; S86-C434 PolarHBondContact OG-O 3.45Å; S86-W438 WeakPolarHBondContact O-CZ3 3.41Å; S86-W438 VanDerWaalsContact OG-CE3 3.3Å
87	I	94.1	Very high	94.7	Very high	1 Å²	1	7.6 Å²	7.6	1%	0.005	4%	0.04	C	C	.	.	H	α-helix	trans	-69.7	-36.1	175.2	-55.2	169	0	0	0	110.7	L84 K90 Q91 Y333 F437 Y450	L84-I87 HydrophobicContact CD2-CD1 4Å; L84-I87 WeakPolarHBondContact O-CA 3.41Å; L84-I87 WeakPolarHBondContact O-CB 3.42Å; L84-I87 PolarHBondContact O-N 2.96Å; I87-K90 VanDerWaalsContact O-CB 3.24Å; I87-K90 WeakPolarHBondContact O-CB 3.24Å; I87-K90 PolarHBondContact O-N 3.37Å; I87-Q91 PolarHBondContact O-N 3.37Å; I87-Y333 HydrophobicContact CG2-CE2 4.43Å; I87-Y333 WeakPolarHBondContact CG2-OH 3.46Å; I87-F437 HydrophobicContact CD1-CB 3.34Å; I87-F437 HydrophobicContact CD1-CG 4.43Å; I87-F437 HydrophobicContact CG1-CB 4.09Å; I87-Y450 HydrophobicContact CD1-CD2 3.96Å; I87-Y450 HydrophobicContact CD1-CE2 3.51Å
88	Y	94.8	Very high	94.7	Very high	4 Å²	4	8.6 Å²	8.6	2%	0.016	5%	0.045	C	C	.	.	H	α-helix	trans	-57.5	-49.1	171.6	169.9	-111.2	0	0	0	111.2	L84 I85 S86 K90 Q91 L92 M145 Y333 F337	L84-Y88 PolarHBondContact O-N 3.08Å; I85-Y88 WeakPolarHBondContact O-CB 3.23Å; I85-Y88 PolarHBondContact O-N 3.5Å; S86-Y88 VanDerWaalsContact C-N 3.34Å; Y88-K90 VanDerWaalsContact C-N 3.27Å; Y88-K90 PolarHBondContact O-N 2.9Å; Y88-Q91 WeakPolarHBondContact O-CA 3.27Å; Y88-Q91 WeakPolarHBondContact O-CB 3.43Å; Y88-Q91 PolarHBondContact O-N 3.29Å; Y88-L92 HydrophobicContact CD1-CD1 4.34Å; Y88-L92 HydrophobicContact CE1-CD1 3.7Å; Y88-L92 HydrophobicContact CE1-CG 4.34Å; Y88-L92 HydrophobicContact CE2-CD1 4.33Å; Y88-L92 HydrophobicContact CE2-CD2 3.94Å; Y88-L92 HydrophobicContact CE2-CG 4.18Å; Y88-L92 PolarHBondContact O-N 3.49Å; Y88-L92 VanDerWaalsContact O-N 3.08Å; Y88-M145 PolarHBondContact OH-O 3.38Å; Y88-Y333 HydrophobicContact CD2-CD2 4.03Å; Y88-Y333 AromaticContact CD2-CG 3.96Å; Y88-Y333 HydrophobicContact CD2-CG 3.96Å; Y88-Y333 HydrophobicContact CG-CG 4.46Å; Y88-F337 AromaticContact CD1-CE2 3.99Å; Y88-F337 HydrophobicContact CD1-CE2 3.99Å; Y88-F337 AromaticContact CD1-CZ 3.76Å; Y88-F337 HydrophobicContact CD1-CZ 3.76Å; Y88-F337 HydrophobicContact CD2-CE2 4.12Å; Y88-F337 AromaticContact CE1-CE2 3.77Å; Y88-F337 HydrophobicContact CE1-CE2 3.77Å; Y88-F337 AromaticContact CE1-CZ 3.53Å; Y88-F337 HydrophobicContact CE1-CZ 3.53Å; Y88-F337 AromaticContact CE2-CE2 3.9Å; Y88-F337 HydrophobicContact CE2-CE2 3.9Å; Y88-F337 HydrophobicContact CG-CE2 4.15Å; Y88-F337 HydrophobicContact CG-CZ 4.34Å; Y88-F337 AromaticContact CZ-CE2 3.7Å; Y88-F337 AromaticContact CZ-CZ 3.92Å
89	F	96	Very high	94.8	Very high	1 Å²	1	7.3 Å²	7.3	0%	0.004	4%	0.039	C	C	.	.	H	α-helix	trans	-59.1	-37.2	175	-61.7	-33.5	0	0	0	112.9	I85 S86 Q91 L92 M94 A99 L102 V103 L258 I262	I85-F89 HydrophobicContact CD1-CE2 4.34Å; I85-F89 HydrophobicContact CD1-CZ 3.93Å; I85-F89 HydrophobicContact CG1-CE1 4.24Å; I85-F89 HydrophobicContact CG1-CE2 3.85Å; I85-F89 HydrophobicContact CG1-CZ 3.65Å; I85-F89 WeakPolarHBondContact O-CD2 3.11Å; I85-F89 WeakPolarHBondContact O-CG 3.38Å; I85-F89 PolarHBondContact O-N 3.44Å; S86-F89 PolarHBondContact O-N 2.84Å; F89-Q91 VanDerWaalsContact C-N 3.34Å; F89-Q91 PolarHBondContact O-N 3.46Å; F89-L92 HydrophobicContact CD1-CD1 4.44Å; F89-L92 PolarHBondContact O-N 3.01Å; F89-M94 HydrophobicContact CB-CB 4.37Å; F89-M94 HydrophobicContact CB-CG 4.48Å; F89-M94 HydrophobicContact CB-SD 3.88Å; F89-M94 HydrophobicContact CD1-SD 4.23Å; F89-M94 HydrophobicContact CG-SD 4.17Å; F89-M94 VanDerWaalsContact O-CB 3.24Å; F89-M94 WeakPolarHBondContact O-CB 3.08Å; F89-M94 WeakPolarHBondContact O-CG 3.33Å; F89-M94 PolarHBondContact O-N 2.96Å; F89-M94 VanDerWaalsContact O-N 3.09Å; F89-A99 HydrophobicContact CB-CB 4.02Å; F89-A99 HydrophobicContact CD2-CB 4.22Å; F89-L102 HydrophobicContact CD1-CD1 3.93Å; F89-L102 HydrophobicContact CD2-CB 4.08Å; F89-L102 HydrophobicContact CD2-CD1 3.9Å; F89-L102 HydrophobicContact CE1-CD1 3.84Å; F89-L102 HydrophobicContact CE2-CB 3.51Å; F89-L102 HydrophobicContact CE2-CD1 3.8Å; F89-L102 HydrophobicContact CE2-CG 4.32Å; F89-L102 HydrophobicContact CG-CD1 3.97Å; F89-L102 HydrophobicContact CZ-CB 3.95Å; F89-L102 HydrophobicContact CZ-CD1 3.77Å; F89-V103 HydrophobicContact CD2-CG2 4.39Å; F89-V103 HydrophobicContact CE2-CG2 4.07Å; F89-L258 HydrophobicContact CD1-CD1 4.32Å; F89-L258 HydrophobicContact CE1-CD1 4.08Å; F89-I262 HydrophobicContact CZ-CD1 3.81Å
90	K	94.9	Very high	95	Very high	3 Å²	3	7.3 Å²	7.3	1%	0.013	4%	0.039	C	C	.	.	H	α-helix	trans	-59.8	-42.2	172.2	-165.1	-176.8	179.4	-178.2	0	112.4	S86 I87 Y88 L92 G93 S216 W438 D442	S86-K90 PolarHBondContact O-N 2.67Å; I87-K90 VanDerWaalsContact O-CB 3.24Å; I87-K90 WeakPolarHBondContact O-CB 3.24Å; I87-K90 PolarHBondContact O-N 3.37Å; Y88-K90 VanDerWaalsContact C-N 3.27Å; Y88-K90 PolarHBondContact O-N 2.9Å; K90-L92 VanDerWaalsContact C-N 3.3Å; K90-L92 PolarHBondContact O-N 3.4Å; K90-G93 PolarHBondContact O-N 3.36Å; K90-S216 WeakPolarHBondContact CG-OG 3.46Å; K90-W438 HydrophobicContact CB-CD2 4.35Å; K90-W438 HydrophobicContact CB-CE3 3.88Å; K90-W438 HydrophobicContact CB-CH2 3.61Å; K90-W438 HydrophobicContact CB-CZ2 4.1Å; K90-W438 HydrophobicContact CB-CZ3 3.49Å; K90-W438 VanDerWaalsContact CB-CZ3 3.49Å; K90-W438 HydrophobicContact CD-CD2 3.7Å; K90-W438 HydrophobicContact CD-CE3 4.04Å; K90-W438 HydrophobicContact CD-CG 4.17Å; K90-W438 HydrophobicContact CD-CH2 4.24Å; K90-W438 HydrophobicContact CD-CZ2 3.91Å; K90-W438 HydrophobicContact CD-CZ3 4.31Å; K90-W438 HydrophobicContact CG-CD2 4.23Å; K90-W438 HydrophobicContact CG-CE3 4.24Å; K90-W438 HydrophobicContact CG-CH2 3.68Å; K90-W438 HydrophobicContact CG-CZ2 3.64Å; K90-W438 HydrophobicContact CG-CZ3 3.99Å; K90-W438 PolarHBondContact NZ-O 3.09Å; K90-D442 IonicContact NZ-OD1 3.79Å; K90-D442 PolarHBondContact NZ-OD1 3.05Å; K90-D442 IonicContact NZ-OD2 3.51Å; K90-D442 PolarHBondContact NZ-OD2 2.62Å
91	Q	92.3	Very high	95.1	Very high	23 Å²	23	9.6 Å²	9.6	11%	0.107	5%	0.051	C	C	.	.	H	α-helix	trans	-67.2	-30.1	178.3	-173	170.2	-66.4	0	0	112.3	I87 Y88 F89 G93 Y246 E330 K331	I87-Q91 PolarHBondContact O-N 3.37Å; Y88-Q91 WeakPolarHBondContact O-CA 3.27Å; Y88-Q91 WeakPolarHBondContact O-CB 3.43Å; Y88-Q91 PolarHBondContact O-N 3.29Å; F89-Q91 VanDerWaalsContact C-N 3.34Å; F89-Q91 PolarHBondContact O-N 3.46Å; Q91-G93 PolarHBondContact O-N 3.06Å; Q91-Y246 PolarHBondContact O-OH 3.21Å; Q91-E330 HydrophobicContact CG-CG 4.23Å; Q91-K331 PolarHBondContact NE2-O 3.27Å; Q91-K331 PolarHBondContact OE1-O 2.97Å
92	L	93.4	Very high	95.2	Very high	4 Å²	4	9.6 Å²	9.6	2%	0.021	5%	0.051	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.9	2.5	170	-57.2	-176.6	0	0	0	113.4	Y88 F89 K90 M94 Q149 P150 L258	Y88-L92 HydrophobicContact CD1-CD1 4.34Å; Y88-L92 HydrophobicContact CE1-CD1 3.7Å; Y88-L92 HydrophobicContact CE1-CG 4.34Å; Y88-L92 HydrophobicContact CE2-CD1 4.33Å; Y88-L92 HydrophobicContact CE2-CD2 3.94Å; Y88-L92 HydrophobicContact CE2-CG 4.18Å; Y88-L92 PolarHBondContact O-N 3.49Å; Y88-L92 VanDerWaalsContact O-N 3.08Å; F89-L92 HydrophobicContact CD1-CD1 4.44Å; F89-L92 PolarHBondContact O-N 3.01Å; K90-L92 VanDerWaalsContact C-N 3.3Å; K90-L92 PolarHBondContact O-N 3.4Å; L92-M94 HydrophobicContact CD1-CE 4.35Å; L92-Q149 HydrophobicContact CD2-CB 4.29Å; L92-Q149 HydrophobicContact CD2-CG 4.09Å; L92-P150 HydrophobicContact CB-CG 4.3Å; L92-P150 WeakPolarHBondContact O-CG 3.45Å; L92-L258 HydrophobicContact CD1-CD1 4.06Å
93	G	92.7	Very high	95.3	Very high	1 Å²	1	9.6 Å²	9.6	1%	0.01	5%	0.052	C	C	.	.	T	Hydrogen-bonded Turn	trans	82.3	13.1	179.9	0	0	0	0	0	114.2	K90 Q91 P217	K90-G93 PolarHBondContact O-N 3.36Å; Q91-G93 PolarHBondContact O-N 3.06Å; G93-P217 WeakPolarHBondContact O-CB 3.5Å; G93-P217 WeakPolarHBondContact O-CD 3.37Å; G93-P217 WeakPolarHBondContact O-CG 3.42Å
94	M	95.8	Very high	95.4	Very high	0 Å²	0	9.1 Å²	9.1	0%	0	5%	0.049	C	C	.	.			trans	-74.6	150.4	178	-60.2	-171.6	179	0	0	112.1	F89 L92 Q98 L102 V251 V254 F255 L258	F89-M94 HydrophobicContact CB-CB 4.37Å; F89-M94 HydrophobicContact CB-CG 4.48Å; F89-M94 HydrophobicContact CB-SD 3.88Å; F89-M94 HydrophobicContact CD1-SD 4.23Å; F89-M94 HydrophobicContact CG-SD 4.17Å; F89-M94 VanDerWaalsContact O-CB 3.24Å; F89-M94 WeakPolarHBondContact O-CB 3.08Å; F89-M94 WeakPolarHBondContact O-CG 3.33Å; F89-M94 PolarHBondContact O-N 2.96Å; F89-M94 VanDerWaalsContact O-N 3.09Å; L92-M94 HydrophobicContact CD1-CE 4.35Å; M94-Q98 HydrophobicContact CB-CB 4.02Å; M94-Q98 HydrophobicContact SD-CB 4.38Å; M94-L102 HydrophobicContact CE-CD1 4.06Å; M94-L102 HydrophobicContact SD-CD1 3.57Å; M94-L102 VanDerWaalsContact SD-CD1 3.57Å; M94-V251 HydrophobicContact CG-CG1 3.94Å; M94-V254 HydrophobicContact CE-CG1 3.91Å; M94-F255 HydrophobicContact CE-CB 3.91Å; M94-F255 HydrophobicContact SD-CB 4.38Å; M94-F255 HydrophobicContact SD-CD2 4.37Å; M94-L258 HydrophobicContact CE-CD1 3.46Å; M94-L258 VanDerWaalsContact CE-CD1 3.46Å
95	N	95.5	Very high	95.4	Very high	39 Å²	39	11.4 Å²	11.4	21%	0.209	6%	0.06	C	C	.	.			trans	-82.8	163.3	172.8	70.9	40.5	0	0	0	112	T97 Q98 A99 S216	N95-T97 PolarHBondContact O-N 2.7Å; N95-T97 WeakPolarHBondContact OD1-CA 3.39Å; N95-T97 VanDerWaalsContact OD1-CB 3.28Å; N95-T97 WeakPolarHBondContact OD1-CB 3.25Å; N95-T97 PolarHBondContact OD1-N 2.83Å; N95-Q98 PolarHBondContact ND2-OE1 3.06Å; N95-Q98 WeakPolarHBondContact O-CB 3.44Å; N95-Q98 PolarHBondContact O-N 3.37Å; N95-Q98 VanDerWaalsContact O-N 3.13Å; N95-Q98 WeakPolarHBondContact OD1-CG 3.32Å; N95-Q98 PolarHBondContact OD1-N 3.39Å; N95-A99 PolarHBondContact O-N 3.19Å; N95-S216 WeakPolarHBondContact CA-O 3.46Å; N95-S216 VanDerWaalsContact CB-O 3.27Å; N95-S216 WeakPolarHBondContact CB-O 3.39Å
96	P	96.5	Very high	95.3	Very high	0 Å²	0	12 Å²	12	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-57.4	-31.6	179.4	-24.6	30.3	0	0	0	113.8	G100 G214 S216 F435 W438 G559 I562	P96-G100 WeakPolarHBondContact O-CA 3.5Å; P96-G100 PolarHBondContact O-N 3.09Å; P96-G214 WeakPolarHBondContact CG-O 3.15Å; P96-S216 WeakPolarHBondContact CD-O 3.42Å; P96-F435 HydrophobicContact CB-CE1 3.89Å; P96-F435 HydrophobicContact CB-CZ 4.42Å; P96-W438 HydrophobicContact CB-CZ2 4.23Å; P96-W438 HydrophobicContact CG-CH2 4.37Å; P96-W438 HydrophobicContact CG-CZ2 3.64Å; P96-G559 WeakPolarHBondContact O-CA 3.37Å; P96-I562 HydrophobicContact CB-CB 3.91Å; P96-I562 HydrophobicContact CB-CG2 3.73Å; P96-I562 HydrophobicContact CG-CB 4.29Å; P96-I562 HydrophobicContact CG-CG2 3.63Å
97	T	97.2	Very high	95	Very high	33 Å²	33	12.2 Å²	12.2	20%	0.202	6%	0.064	C	C	.	.	H	α-helix	trans	-64.7	-48.2	176.1	-58.7	0	0	0	0	110.9	N95 G100 I101 G559 I560 T563	N95-T97 PolarHBondContact O-N 2.7Å; N95-T97 WeakPolarHBondContact OD1-CA 3.39Å; N95-T97 VanDerWaalsContact OD1-CB 3.28Å; N95-T97 WeakPolarHBondContact OD1-CB 3.25Å; N95-T97 PolarHBondContact OD1-N 2.83Å; T97-G100 PolarHBondContact O-N 3.43Å; T97-I101 HydrophobicContact CG2-CD1 3.89Å; T97-I101 VanDerWaalsContact O-CG1 3.25Å; T97-I101 WeakPolarHBondContact O-CG1 3.39Å; T97-I101 PolarHBondContact O-N 2.93Å; T97-G559 PolarHBondContact N-O 3.11Å; T97-G559 PolarHBondContact OG1-O 3.45Å; T97-I560 HydrophobicContact CG2-CG1 3.86Å; T97-I560 WeakPolarHBondContact OG1-CA 3.44Å; T97-T563 PolarHBondContact N-OG1 2.84Å; T97-T563 VanDerWaalsContact N-OG1 3.1Å; T97-T563 PolarHBondContact OG1-OG1 3.33Å
98	Q	97.5	Very high	94.8	Very high	20 Å²	20	14.9 Å²	14.9	9%	0.093	8%	0.075	C	C	.	.	H	α-helix	trans	-60.7	-50.7	177.3	-73.3	170.7	-43.8	0	0	110.8	M94 N95 G100 I101 L102 F255	M94-Q98 HydrophobicContact CB-CB 4.02Å; M94-Q98 HydrophobicContact SD-CB 4.38Å; N95-Q98 PolarHBondContact ND2-OE1 3.06Å; N95-Q98 WeakPolarHBondContact O-CB 3.44Å; N95-Q98 PolarHBondContact O-N 3.37Å; N95-Q98 VanDerWaalsContact O-N 3.13Å; N95-Q98 WeakPolarHBondContact OD1-CG 3.32Å; N95-Q98 PolarHBondContact OD1-N 3.39Å; Q98-G100 VanDerWaalsContact C-N 3.34Å; Q98-G100 PolarHBondContact O-N 2.7Å; Q98-I101 PolarHBondContact O-N 3.46Å; Q98-L102 WeakPolarHBondContact O-CG 3.46Å; Q98-L102 PolarHBondContact O-N 3.02Å; Q98-F255 HydrophobicContact CB-CD2 3.55Å; Q98-F255 HydrophobicContact CB-CE2 3.74Å; Q98-F255 HydrophobicContact CB-CG 4.18Å; Q98-F255 HydrophobicContact CB-CZ 4.5Å; Q98-F255 HydrophobicContact CG-CD1 4.22Å; Q98-F255 HydrophobicContact CG-CD2 3.72Å; Q98-F255 HydrophobicContact CG-CE1 4.4Å; Q98-F255 HydrophobicContact CG-CE2 3.92Å; Q98-F255 HydrophobicContact CG-CG 3.88Å; Q98-F255 HydrophobicContact CG-CZ 4.25Å; Q98-F255 WeakPolarHBondContact O-CE2 3.19Å
99	A	97.3	Very high	94.7	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-60.6	-43.2	177.4	0	0	0	0	0	112.1	F89 N95 I101 L102 V103 W438	F89-A99 HydrophobicContact CB-CB 4.02Å; F89-A99 HydrophobicContact CD2-CB 4.22Å; N95-A99 PolarHBondContact O-N 3.19Å; A99-I101 VanDerWaalsContact C-N 3.31Å; A99-I101 PolarHBondContact O-N 3.4Å; A99-L102 PolarHBondContact O-N 2.83Å; A99-V103 WeakPolarHBondContact O-CG2 3.43Å; A99-V103 PolarHBondContact O-N 3.38Å; A99-W438 HydrophobicContact CB-CH2 4Å; A99-W438 HydrophobicContact CB-CZ3 3.55Å
100	G	97	Very high	94.2	Very high	0 Å²	0	19.1 Å²	19.1	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-62.2	-34.7	176.3	0	0	0	0	0	113.4	P96 T97 Q98 G104 A555	P96-G100 WeakPolarHBondContact O-CA 3.5Å; P96-G100 PolarHBondContact O-N 3.09Å; T97-G100 PolarHBondContact O-N 3.43Å; Q98-G100 VanDerWaalsContact C-N 3.34Å; Q98-G100 PolarHBondContact O-N 2.7Å; G100-G104 VanDerWaalsContact O-CA 3.23Å; G100-G104 WeakPolarHBondContact O-CA 3.38Å; G100-G104 PolarHBondContact O-N 3.4Å; G100-A555 VanDerWaalsContact CA-O 3.31Å; G100-A555 WeakPolarHBondContact CA-O 3.28Å
101	I	97.4	Very high	93.6	Very high	48 Å²	48	24.1 Å²	24.1	25%	0.246	12%	0.118	C	C	.	.	H	α-helix	trans	-68.9	-48.5	172.7	-68.5	164.4	0	0	0	111.2	T97 Q98 A99 V103 G104 I105 F255 L259 L556	T97-I101 HydrophobicContact CG2-CD1 3.89Å; T97-I101 VanDerWaalsContact O-CG1 3.25Å; T97-I101 WeakPolarHBondContact O-CG1 3.39Å; T97-I101 PolarHBondContact O-N 2.93Å; Q98-I101 PolarHBondContact O-N 3.46Å; A99-I101 VanDerWaalsContact C-N 3.31Å; A99-I101 PolarHBondContact O-N 3.4Å; I101-V103 VanDerWaalsContact C-N 3.34Å; I101-V103 PolarHBondContact O-N 3.31Å; I101-G104 PolarHBondContact O-N 3.16Å; I101-I105 WeakPolarHBondContact O-CB 3.27Å; I101-I105 WeakPolarHBondContact O-CG2 3.14Å; I101-I105 PolarHBondContact O-N 3.15Å; I101-F255 HydrophobicContact CB-CE2 4.28Å; I101-F255 HydrophobicContact CB-CZ 4.33Å; I101-F255 HydrophobicContact CD1-CZ 4.24Å; I101-F255 HydrophobicContact CG2-CE2 4.3Å; I101-F255 HydrophobicContact CG2-CZ 4.11Å; I101-L259 HydrophobicContact CG2-CD1 3.96Å; I101-L556 HydrophobicContact CB-CD2 4.1Å; I101-L556 HydrophobicContact CG1-CD2 3.64Å
102	L	97.1	Very high	93.2	Very high	0 Å²	0	26.5 Å²	26.5	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-63.2	-38.2	-179.3	-64.9	178.3	0	0	0	112.6	F89 M94 Q98 A99 I105 R106 F255 L258 L259 I262	F89-L102 HydrophobicContact CD1-CD1 3.93Å; F89-L102 HydrophobicContact CD2-CB 4.08Å; F89-L102 HydrophobicContact CD2-CD1 3.9Å; F89-L102 HydrophobicContact CE1-CD1 3.84Å; F89-L102 HydrophobicContact CE2-CB 3.51Å; F89-L102 HydrophobicContact CE2-CD1 3.8Å; F89-L102 HydrophobicContact CE2-CG 4.32Å; F89-L102 HydrophobicContact CG-CD1 3.97Å; F89-L102 HydrophobicContact CZ-CB 3.95Å; F89-L102 HydrophobicContact CZ-CD1 3.77Å; M94-L102 HydrophobicContact CE-CD1 4.06Å; M94-L102 HydrophobicContact SD-CD1 3.57Å; M94-L102 VanDerWaalsContact SD-CD1 3.57Å; Q98-L102 WeakPolarHBondContact O-CG 3.46Å; Q98-L102 PolarHBondContact O-N 3.02Å; A99-L102 PolarHBondContact O-N 2.83Å; L102-I105 WeakPolarHBondContact O-CG2 3.32Å; L102-R106 WeakPolarHBondContact O-CG 3.32Å; L102-F255 HydrophobicContact CD1-CD2 4.01Å; L102-F255 HydrophobicContact CD1-CE2 4.47Å; L102-F255 HydrophobicContact CD2-CD2 3.98Å; L102-F255 HydrophobicContact CD2-CE2 3.91Å; L102-F255 HydrophobicContact CG-CD2 3.91Å; L102-F255 HydrophobicContact CG-CE2 3.88Å; L102-L258 HydrophobicContact CD1-CB 4.17Å; L102-L258 HydrophobicContact CD1-CD1 4.43Å; L102-L258 HydrophobicContact CD2-CB 4.11Å; L102-L259 HydrophobicContact CD2-CB 3.81Å; L102-L259 HydrophobicContact CD2-CD1 4.18Å; L102-I262 HydrophobicContact CB-CD1 3.99Å; L102-I262 HydrophobicContact CD2-CD1 4.08Å; L102-I262 HydrophobicContact CG-CD1 4.43Å
103	V	95.2	Very high	92.8	Very high	7 Å²	7	26.3 Å²	26.3	4%	0.042	14%	0.141	C	C	.	.	H	α-helix	trans	-78.4	-41.9	175.8	176.9	0	0	0	0	111	I85 F89 A99 I101 F433 C434 A555	I85-V103 HydrophobicContact CG2-CG2 3.92Å; F89-V103 HydrophobicContact CD2-CG2 4.39Å; F89-V103 HydrophobicContact CE2-CG2 4.07Å; A99-V103 WeakPolarHBondContact O-CG2 3.43Å; A99-V103 PolarHBondContact O-N 3.38Å; I101-V103 VanDerWaalsContact C-N 3.34Å; I101-V103 PolarHBondContact O-N 3.31Å; V103-F433 HydrophobicContact CG1-CD1 3.98Å; V103-F433 HydrophobicContact CG1-CE1 4.01Å; V103-C434 HydrophobicContact CG1-CB 4.23Å; V103-A555 HydrophobicContact CB-CB 4.47Å; V103-A555 HydrophobicContact CG1-CB 4.3Å
104	G	94.3	Very high	92	Very high	1 Å²	1	28 Å²	28	1%	0.01	15%	0.154	C	C	.	.	H	α-helix	trans	-71.8	-27.2	-173.6	0	0	0	0	0	114.3	G100 I101 R106 P107 F108 G552	G100-G104 VanDerWaalsContact O-CA 3.23Å; G100-G104 WeakPolarHBondContact O-CA 3.38Å; G100-G104 PolarHBondContact O-N 3.4Å; I101-G104 PolarHBondContact O-N 3.16Å; G104-R106 VanDerWaalsContact C-N 3.3Å; G104-R106 PolarHBondContact O-N 3.12Å; G104-P107 VanDerWaalsContact O-CD 3.28Å; G104-P107 WeakPolarHBondContact O-CD 3.43Å; G104-F108 WeakPolarHBondContact O-CD2 3.48Å; G104-F108 WeakPolarHBondContact O-CE2 3.37Å; G104-G552 WeakPolarHBondContact O-CA 3.38Å
105	I	94.4	Very high	91	Very high	47 Å²	47	31.8 Å²	31.8	24%	0.241	18%	0.179	C	C	.	.	H	α-helix	trans	-67.9	-29.3	179.1	-167	58.4	0	0	0	112.8	I101 L102 F108 V109 L259 I262	I101-I105 WeakPolarHBondContact O-CB 3.27Å; I101-I105 WeakPolarHBondContact O-CG2 3.14Å; I101-I105 PolarHBondContact O-N 3.15Å; L102-I105 WeakPolarHBondContact O-CG2 3.32Å; I105-F108 WeakPolarHBondContact O-CB 3.5Å; I105-F108 PolarHBondContact O-N 3Å; I105-F108 VanDerWaalsContact O-N 3.13Å; I105-V109 HydrophobicContact CD1-CG2 4.46Å; I105-V109 HydrophobicContact CG1-CG2 4.01Å; I105-V109 WeakPolarHBondContact O-CG2 3.1Å; I105-V109 PolarHBondContact O-N 3.45Å; I105-V109 VanDerWaalsContact O-N 3.09Å; I105-L259 HydrophobicContact CG2-CD1 4.3Å; I105-I262 HydrophobicContact CG2-CG2 4.11Å
106	R	92.4	Very high	90.5	Very high	16 Å²	16	35.1 Å²	35.1	6%	0.06	19%	0.192	C	C	.	.	H	α-helix	trans	-59.6	-50.6	-169.9	-51.5	164.6	54.9	72.4	16.3	112.8	F82 L102 G104 F108 V109 E110 W138 I262 E266	F82-R106 VanDerWaalsContact CE1-NE 3.32Å; F82-R106 VanDerWaalsContact CZ-CZ 3.41Å; L102-R106 WeakPolarHBondContact O-CG 3.32Å; G104-R106 VanDerWaalsContact C-N 3.3Å; G104-R106 PolarHBondContact O-N 3.12Å; R106-F108 VanDerWaalsContact C-N 3.26Å; R106-F108 PolarHBondContact O-N 3.34Å; R106-V109 PolarHBondContact O-N 2.97Å; R106-E110 PolarHBondContact O-N 3.35Å; R106-W138 VanDerWaalsContact NH2-CZ3 3.33Å; R106-I262 HydrophobicContact CG-CG2 3.74Å; R106-E266 HydrophobicContact CB-CG 3.92Å; R106-E266 HydrophobicContact CG-CG 3.91Å; R106-E266 IonicContact CZ-OE1 3.55Å; R106-E266 IonicContact CZ-OE2 3.67Å; R106-E266 VanDerWaalsContact CZ-OE2 3.29Å; R106-E266 IonicContact NE-OE2 2.7Å; R106-E266 IonicContact NH1-OE1 2.99Å; R106-E266 PolarHBondContact NH1-OE1 2.92Å; R106-E266 IonicContact NH1-OE2 2.83Å; R106-E266 IonicContact NH2-OE1 4Å; R106-E266 PolarHBondContact NH2-OE1 2.58Å; R106-E266 IonicContact NH2-OE2 2.89Å; R106-E266 PolarHBondContact NH2-OE2 3.22Å
107	P	89.4	Confident	89.9	Confident	8 Å²	8	35.9 Å²	35.9	5%	0.052	20%	0.195	C	C	.	.	H	α-helix	trans	-66.8	-25.2	179.3	-18.5	34.2	0	0	0	113.5	G104 F111 F547	G104-P107 VanDerWaalsContact O-CD 3.28Å; G104-P107 WeakPolarHBondContact O-CD 3.43Å; P107-F111 WeakPolarHBondContact O-CB 3.33Å; P107-F111 PolarHBondContact O-N 3.49Å; P107-F547 VanDerWaalsContact CB-O 3.32Å; P107-F547 WeakPolarHBondContact CB-O 3.47Å
108	F	90.3	Very high	88.4	Confident	58 Å²	58	35.6 Å²	35.6	25%	0.254	20%	0.199	S	C	.	.	H	α-helix	trans	-70	-43.4	173.5	-64.4	-79.6	0	0	0	111.4	G104 I105 R106 F111 A112 L549 L556	G104-F108 WeakPolarHBondContact O-CD2 3.48Å; G104-F108 WeakPolarHBondContact O-CE2 3.37Å; I105-F108 WeakPolarHBondContact O-CB 3.5Å; I105-F108 PolarHBondContact O-N 3Å; I105-F108 VanDerWaalsContact O-N 3.13Å; R106-F108 VanDerWaalsContact C-N 3.26Å; R106-F108 PolarHBondContact O-N 3.34Å; F108-F111 PolarHBondContact O-N 3.46Å; F108-A112 WeakPolarHBondContact O-CB 3.48Å; F108-A112 PolarHBondContact O-N 3.23Å; F108-L549 HydrophobicContact CE1-CD1 3.62Å; F108-L549 HydrophobicContact CZ-CD1 4.26Å; F108-L556 HydrophobicContact CE2-CD1 3.52Å; F108-L556 HydrophobicContact CE2-CG 4.5Å; F108-L556 HydrophobicContact CZ-CD1 3.97Å
109	V	92.3	Very high	87.1	Confident	17 Å²	17	36.7 Å²	36.7	10%	0.103	22%	0.215	C	C	.	.	H	α-helix	trans	-65.2	-43.8	176.7	177	0	0	0	0	110.4	I105 R106 A112 S113 T263 E266 F267	I105-V109 HydrophobicContact CD1-CG2 4.46Å; I105-V109 HydrophobicContact CG1-CG2 4.01Å; I105-V109 WeakPolarHBondContact O-CG2 3.1Å; I105-V109 PolarHBondContact O-N 3.45Å; I105-V109 VanDerWaalsContact O-N 3.09Å; R106-V109 PolarHBondContact O-N 2.97Å; V109-A112 PolarHBondContact O-N 3.09Å; V109-S113 WeakPolarHBondContact O-CB 3.39Å; V109-S113 PolarHBondContact O-N 3.48Å; V109-S113 PolarHBondContact O-OG 2.97Å; V109-T263 HydrophobicContact CG2-CG2 3.96Å; V109-E266 HydrophobicContact CB-CB 4.06Å; V109-E266 HydrophobicContact CG1-CB 3.72Å; V109-F267 HydrophobicContact CG1-CB 3.74Å; V109-F267 VanDerWaalsContact CG1-N 3.34Å
110	E	85.9	Confident	86.2	Confident	76 Å²	76	39 Å²	39	36%	0.355	23%	0.227	S	C	.	.	H	α-helix	trans	-59.3	-47.4	175.2	-171.6	-178.7	173.9	0	0	111.3	R106 A112 S113 A114 A270	R106-E110 PolarHBondContact O-N 3.35Å; E110-A112 PolarHBondContact O-N 3.15Å; E110-S113 WeakPolarHBondContact CA-OG 3.36Å; E110-S113 PolarHBondContact O-N 2.96Å; E110-S113 PolarHBondContact O-OG 3.35Å; E110-S113 VanDerWaalsContact O-OG 3.08Å; E110-A114 WeakPolarHBondContact O-CB 3.37Å; E110-A114 PolarHBondContact O-N 3.17Å; E110-A270 HydrophobicContact CG-CB 4.34Å
111	F	80.9	Confident	85.1	Confident	108 Å²	108	39.2 Å²	39.2	47%	0.474	23%	0.229	S	C	.	.	H	α-helix	trans	-62.2	-42.1	178	-179.5	-105.7	0	0	0	112.7	P107 F108 P115 G544	P107-F111 WeakPolarHBondContact O-CB 3.33Å; P107-F111 PolarHBondContact O-N 3.49Å; F108-F111 PolarHBondContact O-N 3.46Å; F111-P115 WeakPolarHBondContact O-CD 3.41Å; F111-G544 VanDerWaalsContact CE2-CA 3.49Å
112	A	84.1	Confident	83.8	Confident	73 Å²	73	43 Å²	43	60%	0.603	25%	0.25	S	C	*	.	H	α-helix	trans	-72.1	-32.7	179.3	0	0	0	0	0	113.1	F108 V109 E110	F108-A112 WeakPolarHBondContact O-CB 3.48Å; F108-A112 PolarHBondContact O-N 3.23Å; V109-A112 PolarHBondContact O-N 3.09Å; E110-A112 PolarHBondContact O-N 3.15Å
113	S	86.1	Confident	82.9	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-84.7	-25.9	-176.6	59.4	0	0	0	0	113.5	V109 E110 F116 W117 A270	V109-S113 WeakPolarHBondContact O-CB 3.39Å; V109-S113 PolarHBondContact O-N 3.48Å; V109-S113 PolarHBondContact O-OG 2.97Å; E110-S113 WeakPolarHBondContact CA-OG 3.36Å; E110-S113 PolarHBondContact O-N 2.96Å; E110-S113 PolarHBondContact O-OG 3.35Å; E110-S113 VanDerWaalsContact O-OG 3.08Å; S113-F116 WeakPolarHBondContact O-CB 3.5Å; S113-F116 PolarHBondContact O-N 2.99Å; S113-F116 VanDerWaalsContact O-N 3.11Å; S113-W117 PolarHBondContact O-N 3.35Å; S113-A270 WeakPolarHBondContact OG-CB 3.44Å
114	A	75.4	Confident	82.2	Confident	36 Å²	36	58.4 Å²	58.4	30%	0.298	31%	0.311	S	S	.	.	H	α-helix	trans	-55.4	-46.7	-176.9	0	0	0	0	0	114.2	E110 F116 G118	E110-A114 WeakPolarHBondContact O-CB 3.37Å; E110-A114 PolarHBondContact O-N 3.17Å; A114-F116 VanDerWaalsContact C-N 3.33Å; A114-F116 PolarHBondContact O-N 2.91Å; A114-G118 PolarHBondContact O-N 2.9Å
115	P	76.1	Confident	81.3	Confident	80 Å²	80	67.8 Å²	67.8	52%	0.519	35%	0.346	S	S	.	.	H	α-helix	trans	-65.6	-35.4	176.9	-20.6	33.4	0	0	0	113.1	F111 G119	F111-P115 WeakPolarHBondContact O-CD 3.41Å; P115-G119 PolarHBondContact O-N 2.91Å; P115-G119 VanDerWaalsContact O-N 3.12Å
116	F	84.6	Confident	80.7	Confident	109 Å²	109	72 Å²	72	48%	0.478	36%	0.363	S	S	.	.	H	α-helix	trans	-63.1	-50.5	179.7	171.9	-95.5	0	0	0	110.9	S113 A114 L120 F267	S113-F116 WeakPolarHBondContact O-CB 3.5Å; S113-F116 PolarHBondContact O-N 2.99Å; S113-F116 VanDerWaalsContact O-N 3.11Å; A114-F116 VanDerWaalsContact C-N 3.33Å; A114-F116 PolarHBondContact O-N 2.91Å; F116-L120 HydrophobicContact CE1-CD2 4.47Å; F116-L120 WeakPolarHBondContact O-CB 3.45Å; F116-L120 PolarHBondContact O-N 3.34Å; F116-F267 AromaticContact CD1-CZ 3.9Å; F116-F267 HydrophobicContact CD1-CZ 3.9Å; F116-F267 HydrophobicContact CE1-CE1 4.35Å; F116-F267 AromaticContact CE1-CZ 3.96Å; F116-F267 HydrophobicContact CE1-CZ 3.96Å; F116-F267 HydrophobicContact CG-CZ 4.49Å
117	W	82.6	Confident	80.2	Confident	17 Å²	17	71.7 Å²	71.7	6%	0.064	36%	0.364	C	S	.	.	H	α-helix	trans	-75.1	-31.6	-178.8	-67.3	111.8	0	0	0	113.7	S113 L120 A121 V130 F133 F267 F268 P271	S113-W117 PolarHBondContact O-N 3.35Å; W117-L120 HydrophobicContact CE3-CB 4.49Å; W117-L120 HydrophobicContact CE3-CD2 3.52Å; W117-L120 HydrophobicContact CH2-CD2 4.43Å; W117-L120 HydrophobicContact CZ3-CD2 3.39Å; W117-L120 PolarHBondContact O-N 3.15Å; W117-A121 WeakPolarHBondContact O-CB 3.44Å; W117-A121 PolarHBondContact O-N 3.4Å; W117-V130 HydrophobicContact CE3-CG1 3.87Å; W117-V130 HydrophobicContact CZ3-CG1 4.34Å; W117-F133 HydrophobicContact CH2-CE1 4.03Å; W117-F267 HydrophobicContact CZ2-CD1 4.28Å; W117-F267 AromaticContact CZ2-CE1 3.88Å; W117-F267 HydrophobicContact CZ2-CE1 3.88Å; W117-F267 PolarHBondContact NE1-O 2.81Å; W117-F268 AromaticContact CH2-CD1 3.88Å; W117-F268 HydrophobicContact CH2-CD1 3.88Å; W117-F268 HydrophobicContact CH2-CE1 4.3Å; W117-F268 AromaticContact CZ2-CD1 3.62Å; W117-F268 HydrophobicContact CZ2-CD1 3.62Å; W117-F268 HydrophobicContact CZ2-CE1 4.19Å; W117-P271 HydrophobicContact CB-CB 3.46Å; W117-P271 VanDerWaalsContact CB-CB 3.46Å; W117-P271 HydrophobicContact CB-CG 3.75Å; W117-P271 HydrophobicContact CD2-CG 3.79Å; W117-P271 HydrophobicContact CE3-CG 4.26Å; W117-P271 HydrophobicContact CG-CB 3.83Å; W117-P271 HydrophobicContact CG-CG 3.53Å
118	G	67.3	Low	80.2	Confident	27 Å²	27	74.8 Å²	74.8	28%	0.278	38%	0.377	S	S	.	.	H	α-helix	trans	-57.9	-51.7	171.2	0	0	0	0	0	111.2	A114 L120 A121 D122	A114-G118 PolarHBondContact O-N 2.9Å; G118-L120 VanDerWaalsContact C-N 3.31Å; G118-L120 PolarHBondContact O-N 3.5Å; G118-A121 PolarHBondContact O-N 3.32Å; G118-D122 PolarHBondContact O-N 3.06Å; G118-D122 VanDerWaalsContact O-N 3.15Å
119	G	69.1	Low	80.2	Confident	43 Å²	43	74.7 Å²	74.7	44%	0.443	39%	0.387	S	S	.	.	H	α-helix	trans	-63.4	-34.1	176.6	0	0	0	0	0	113.7	P115 R123	P115-G119 PolarHBondContact O-N 2.91Å; P115-G119 VanDerWaalsContact O-N 3.12Å; G119-R123 VanDerWaalsContact O-CB 3.22Å; G119-R123 WeakPolarHBondContact O-CB 3.41Å; G119-R123 PolarHBondContact O-N 2.95Å
120	L	79.1	Confident	80.1	Confident	48 Å²	48	74.7 Å²	74.7	25%	0.251	39%	0.387	S	S	.	.	H	α-helix	trans	-68.1	-44.8	177.2	-160.8	72.7	0	0	0	112.2	F116 W117 G118 D122 R123 F124	F116-L120 HydrophobicContact CE1-CD2 4.47Å; F116-L120 WeakPolarHBondContact O-CB 3.45Å; F116-L120 PolarHBondContact O-N 3.34Å; W117-L120 HydrophobicContact CE3-CB 4.49Å; W117-L120 HydrophobicContact CE3-CD2 3.52Å; W117-L120 HydrophobicContact CH2-CD2 4.43Å; W117-L120 HydrophobicContact CZ3-CD2 3.39Å; W117-L120 PolarHBondContact O-N 3.15Å; G118-L120 VanDerWaalsContact C-N 3.31Å; G118-L120 PolarHBondContact O-N 3.5Å; L120-D122 VanDerWaalsContact C-N 3.34Å; L120-D122 PolarHBondContact O-N 3.35Å; L120-R123 PolarHBondContact O-N 2.9Å; L120-F124 HydrophobicContact CD1-CD2 3.73Å; L120-F124 HydrophobicContact CD1-CE2 3.42Å; L120-F124 VanDerWaalsContact CD1-CE2 3.42Å; L120-F124 HydrophobicContact CG-CD2 3.86Å; L120-F124 HydrophobicContact CG-CE2 4.05Å; L120-F124 WeakPolarHBondContact O-CD2 3.48Å; L120-F124 PolarHBondContact O-N 3.09Å
121	A	73.6	Confident	80.3	Confident	5 Å²	5	71.1 Å²	71.1	4%	0.041	37%	0.37	C	S	.	.	H	α-helix	trans	-62.5	-42.5	179.5	0	0	0	0	0	111.5	W117 G118 R125 L275	W117-A121 WeakPolarHBondContact O-CB 3.44Å; W117-A121 PolarHBondContact O-N 3.4Å; G118-A121 PolarHBondContact O-N 3.32Å; A121-R125 WeakPolarHBondContact O-CA 3.4Å; A121-R125 PolarHBondContact O-N 3.49Å; A121-L275 HydrophobicContact CB-CD2 3.69Å
122	D	70.7	Confident	81	Confident	127 Å²	127	67.6 Å²	67.6	68%	0.679	36%	0.356	S	S	*	.	H	α-helix	trans	-67.3	-44.9	177.2	-67.8	-18.2	0	0	0	111.5	G118 L120 F124 R125	G118-D122 PolarHBondContact O-N 3.06Å; G118-D122 VanDerWaalsContact O-N 3.15Å; L120-D122 VanDerWaalsContact C-N 3.34Å; L120-D122 PolarHBondContact O-N 3.35Å; D122-F124 PolarHBondContact O-N 3.12Å; D122-R125 PolarHBondContact O-N 3.27Å
123	R	77.3	Confident	81.5	Confident	207 Å²	207	68.4 Å²	68.4	78%	0.781	35%	0.346	S	S	*	.	H	α-helix	trans	-63	-43.3	-178.6	-176.5	174.9	-174.2	178.2	2.1	112.8	G119 L120	G119-R123 VanDerWaalsContact O-CB 3.22Å; G119-R123 WeakPolarHBondContact O-CB 3.41Å; G119-R123 PolarHBondContact O-N 2.95Å; L120-R123 PolarHBondContact O-N 2.9Å
124	F	80.4	Confident	81.9	Confident	124 Å²	124	68.4 Å²	68.4	54%	0.544	35%	0.346	S	S	.	.	H	α-helix	trans	-88.7	-8.1	-177.8	-73.9	-71.8	0	0	0	113.5	L120 D122 K126	L120-F124 HydrophobicContact CD1-CD2 3.73Å; L120-F124 HydrophobicContact CD1-CE2 3.42Å; L120-F124 VanDerWaalsContact CD1-CE2 3.42Å; L120-F124 HydrophobicContact CG-CD2 3.86Å; L120-F124 HydrophobicContact CG-CE2 4.05Å; L120-F124 WeakPolarHBondContact O-CD2 3.48Å; L120-F124 PolarHBondContact O-N 3.09Å; D122-F124 PolarHBondContact O-N 3.12Å; F124-K126 HydrophobicContact CB-CB 4.33Å; F124-K126 WeakPolarHBondContact O-CG 3.19Å; F124-K126 PolarHBondContact O-N 3.24Å; F124-K126 VanDerWaalsContact O-N 3.09Å
125	R	76.2	Confident	82.9	Confident	197 Å²	197	66.7 Å²	66.7	74%	0.743	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	50.5	30.4	-174.4	-57.7	-178	-178.7	177.5	-1.1	113.1	A121 D122	A121-R125 WeakPolarHBondContact O-CA 3.4Å; A121-R125 PolarHBondContact O-N 3.49Å; D122-R125 PolarHBondContact O-N 3.27Å
126	K	81.7	Confident	83.9	Confident	137 Å²	137	66.7 Å²	66.7	60%	0.596	33%	0.327	S	S	*	.			trans	-121.9	44	-174	-78.3	-179.6	-178.9	-175.7	0	111.4	F124 K128 A129 V130	F124-K126 HydrophobicContact CB-CB 4.33Å; F124-K126 WeakPolarHBondContact O-CG 3.19Å; F124-K126 PolarHBondContact O-N 3.24Å; F124-K126 VanDerWaalsContact O-N 3.09Å; K126-K128 PolarHBondContact O-N 3.38Å; K126-A129 HydrophobicContact CB-CB 4.21Å; K126-A129 PolarHBondContact O-N 2.62Å; K126-V130 PolarHBondContact O-N 3.38Å; K126-V130 VanDerWaalsContact O-N 3.15Å
127	G	81.9	Confident	84.4	Confident	9 Å²	9	62.5 Å²	62.5	9%	0.093	31%	0.311	C	S	.	.	H	α-helix	trans	-51	-41.1	-178.9	0	0	0	0	0	113.3	A129 V130 L131	G127-A129 PolarHBondContact O-N 3.31Å; G127-V130 PolarHBondContact O-N 3.13Å; G127-L131 WeakPolarHBondContact O-CB 3.45Å; G127-L131 PolarHBondContact O-N 2.99Å
128	K	88.2	Confident	85	Confident	73 Å²	73	62.2 Å²	62.2	32%	0.317	31%	0.31	S	S	.	.	H	α-helix	trans	-59	-46.1	175.1	-168.7	171.5	-178.5	161.7	0	113.6	K126 V130 L131 L132 T352 F354 F356	K126-K128 PolarHBondContact O-N 3.38Å; K128-V130 VanDerWaalsContact C-N 3.33Å; K128-L131 PolarHBondContact O-N 3.07Å; K128-L132 HydrophobicContact CG-CD1 4.22Å; K128-L132 HydrophobicContact CG-CG 4.49Å; K128-L132 VanDerWaalsContact O-CG 3.32Å; K128-L132 WeakPolarHBondContact O-CG 3.11Å; K128-L132 PolarHBondContact O-N 3.13Å; K128-T352 VanDerWaalsContact CE-O 3.24Å; K128-T352 WeakPolarHBondContact CE-O 3.43Å; K128-T352 PolarHBondContact NZ-O 3.09Å; K128-F354 WeakPolarHBondContact CE-O 3.46Å; K128-F354 PolarHBondContact NZ-O 3.47Å; K128-F356 VanDerWaalsContact CA-CE2 3.5Å; K128-F356 HydrophobicContact CB-CD2 3.45Å; K128-F356 VanDerWaalsContact CB-CD2 3.45Å; K128-F356 HydrophobicContact CB-CE2 3.76Å; K128-F356 HydrophobicContact CB-CG 4.12Å; K128-F356 HydrophobicContact CD-CD2 4.43Å; K128-F356 HydrophobicContact CG-CD2 4.04Å; K128-F356 HydrophobicContact CG-CE2 4.15Å
129	A	90.2	Very high	86.4	Confident	56 Å²	56	62.2 Å²	62.2	46%	0.463	30%	0.303	S	S	.	.	H	α-helix	trans	-66.7	-39.1	-178.2	0	0	0	0	0	111.1	K126 G127 L132 F133	K126-A129 HydrophobicContact CB-CB 4.21Å; K126-A129 PolarHBondContact O-N 2.62Å; G127-A129 PolarHBondContact O-N 3.31Å; A129-L132 PolarHBondContact O-N 2.98Å; A129-F133 VanDerWaalsContact O-CB 3.27Å; A129-F133 WeakPolarHBondContact O-CB 3.12Å; A129-F133 PolarHBondContact O-N 3.28Å
130	V	90.1	Very high	87.7	Confident	17 Å²	17	64.5 Å²	64.5	10%	0.103	31%	0.308	C	S	.	.	H	α-helix	trans	-65.4	-42.5	175.6	-177.6	0	0	0	0	110.9	W117 K126 G127 K128 F133 A134 P271 L275	W117-V130 HydrophobicContact CE3-CG1 3.87Å; W117-V130 HydrophobicContact CZ3-CG1 4.34Å; K126-V130 PolarHBondContact O-N 3.38Å; K126-V130 VanDerWaalsContact O-N 3.15Å; G127-V130 PolarHBondContact O-N 3.13Å; K128-V130 VanDerWaalsContact C-N 3.33Å; V130-F133 PolarHBondContact O-N 2.97Å; V130-A134 WeakPolarHBondContact O-CB 3.35Å; V130-A134 PolarHBondContact O-N 3.49Å; V130-P271 HydrophobicContact CG1-CB 4.39Å; V130-P271 HydrophobicContact CG1-CG 4.08Å; V130-L275 HydrophobicContact CB-CD1 3.75Å; V130-L275 HydrophobicContact CG1-CD1 3.59Å
131	L	91.2	Very high	88.5	Confident	0 Å²	0	62.6 Å²	62.6	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-59.5	-50.5	175.2	173.5	60.2	0	0	0	111.7	G127 K128 F133 A134 L135 A272 L275 A351 F354 F356	G127-L131 WeakPolarHBondContact O-CB 3.45Å; G127-L131 PolarHBondContact O-N 2.99Å; K128-L131 PolarHBondContact O-N 3.07Å; L131-F133 VanDerWaalsContact C-N 3.35Å; L131-F133 PolarHBondContact O-N 3.08Å; L131-A134 PolarHBondContact O-N 3.45Å; L131-L135 HydrophobicContact CD1-CD1 4.13Å; L131-L135 HydrophobicContact CD1-CG 4.3Å; L131-L135 HydrophobicContact CG-CD1 4.27Å; L131-L135 WeakPolarHBondContact O-CG 3.49Å; L131-L135 PolarHBondContact O-N 2.96Å; L131-A272 HydrophobicContact CD1-CB 4.23Å; L131-A272 WeakPolarHBondContact CD1-O 3.4Å; L131-L275 HydrophobicContact CB-CB 4.27Å; L131-L275 HydrophobicContact CB-CD1 4.17Å; L131-L275 HydrophobicContact CD1-CB 4.44Å; L131-A351 HydrophobicContact CD2-CB 3.99Å; L131-A351 HydrophobicContact CG-CB 4.29Å; L131-F354 HydrophobicContact CD2-CD2 3.7Å; L131-F354 HydrophobicContact CD2-CE2 4.2Å; L131-F356 HydrophobicContact CB-CZ 4.43Å; L131-F356 HydrophobicContact CD2-CE2 4.07Å; L131-F356 HydrophobicContact CD2-CZ 3.93Å
132	L	94.9	Very high	89.5	Confident	35 Å²	35	62.4 Å²	62.4	18%	0.183	30%	0.297	C	S	.	.	H	α-helix	trans	-63.6	-40.9	-179.7	-67.5	178.2	0	0	0	111.9	K128 A129 L135 I136 F348 A351 T352	K128-L132 HydrophobicContact CG-CD1 4.22Å; K128-L132 HydrophobicContact CG-CG 4.49Å; K128-L132 VanDerWaalsContact O-CG 3.32Å; K128-L132 WeakPolarHBondContact O-CG 3.11Å; K128-L132 PolarHBondContact O-N 3.13Å; A129-L132 PolarHBondContact O-N 2.98Å; L132-L135 PolarHBondContact O-N 3.24Å; L132-I136 WeakPolarHBondContact O-CG1 3.34Å; L132-I136 PolarHBondContact O-N 2.84Å; L132-I136 VanDerWaalsContact O-N 3.07Å; L132-F348 HydrophobicContact CB-CE2 3.88Å; L132-F348 HydrophobicContact CD2-CD2 3.94Å; L132-F348 HydrophobicContact CD2-CE2 3.71Å; L132-F348 HydrophobicContact CD2-CZ 4.13Å; L132-F348 HydrophobicContact CG-CE2 4.31Å; L132-A351 HydrophobicContact CD2-CB 3.93Å; L132-T352 HydrophobicContact CD2-CG2 3.98Å
133	F	94.4	Very high	90.6	Very high	89 Å²	89	59.3 Å²	59.3	39%	0.39	28%	0.28	S	S	.	.	H	α-helix	trans	-59.6	-46.8	174	172.7	-99.9	0	0	0	111.6	W117 A129 V130 L131 L135 I136 C137 F268	W117-F133 HydrophobicContact CH2-CE1 4.03Å; A129-F133 VanDerWaalsContact O-CB 3.27Å; A129-F133 WeakPolarHBondContact O-CB 3.12Å; A129-F133 PolarHBondContact O-N 3.28Å; V130-F133 PolarHBondContact O-N 2.97Å; L131-F133 VanDerWaalsContact C-N 3.35Å; L131-F133 PolarHBondContact O-N 3.08Å; F133-L135 VanDerWaalsContact C-N 3.32Å; F133-L135 PolarHBondContact O-N 2.87Å; F133-I136 PolarHBondContact O-N 2.91Å; F133-C137 VanDerWaalsContact CZ-SG 3.55Å; F133-C137 PolarHBondContact O-N 3.12Å; F133-C137 PolarHBondContact O-SG 2.92Å; F133-C137 VanDerWaalsContact O-SG 3.36Å; F133-F268 HydrophobicContact CE1-CB 4.21Å; F133-F268 AromaticContact CE1-CD1 3.73Å; F133-F268 HydrophobicContact CE1-CD1 3.73Å; F133-F268 HydrophobicContact CE1-CG 4.33Å; F133-F268 AromaticContact CZ-CD1 3.88Å; F133-F268 HydrophobicContact CZ-CD1 3.88Å; F133-F268 HydrophobicContact CZ-CE1 4.42Å; F133-F268 HydrophobicContact CZ-CG 4.41Å
134	A	94.4	Very high	91.4	Very high	0 Å²	0	51 Å²	51	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-61.8	-37.9	179.1	0	0	0	0	0	112.8	V130 L131 C137 W138 P271 A272	V130-A134 WeakPolarHBondContact O-CB 3.35Å; V130-A134 PolarHBondContact O-N 3.49Å; L131-A134 PolarHBondContact O-N 3.45Å; A134-C137 PolarHBondContact O-N 2.78Å; A134-W138 PolarHBondContact O-N 2.94Å; A134-P271 HydrophobicContact CB-CG 3.9Å; A134-A272 HydrophobicContact CB-CB 3.9Å
135	L	96.2	Very high	92.1	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-68.8	-36.2	175.6	-66.5	172.5	0	0	0	112.6	F70 F74 L131 L132 F133 W138 I139 A272 M344 F348 A351	F70-L135 HydrophobicContact CE2-CD1 4.05Å; F70-L135 HydrophobicContact CE2-CD2 4.45Å; F74-L135 HydrophobicContact CD2-CD2 3.82Å; F74-L135 HydrophobicContact CE2-CD2 3.73Å; L131-L135 HydrophobicContact CD1-CD1 4.13Å; L131-L135 HydrophobicContact CD1-CG 4.3Å; L131-L135 HydrophobicContact CG-CD1 4.27Å; L131-L135 WeakPolarHBondContact O-CG 3.49Å; L131-L135 PolarHBondContact O-N 2.96Å; L132-L135 PolarHBondContact O-N 3.24Å; F133-L135 VanDerWaalsContact C-N 3.32Å; F133-L135 PolarHBondContact O-N 2.87Å; L135-W138 WeakPolarHBondContact O-CB 3.42Å; L135-W138 PolarHBondContact O-N 3.42Å; L135-I139 WeakPolarHBondContact O-CG1 3.39Å; L135-I139 PolarHBondContact O-N 2.89Å; L135-A272 HydrophobicContact CD2-CB 3.99Å; L135-A272 HydrophobicContact CG-CB 4.41Å; L135-M344 HydrophobicContact CD2-SD 3.6Å; L135-F348 HydrophobicContact CB-CB 4.45Å; L135-F348 HydrophobicContact CB-CD2 3.97Å; L135-F348 HydrophobicContact CD1-CB 4.43Å; L135-F348 HydrophobicContact CD1-CD2 4.48Å; L135-A351 HydrophobicContact CD1-CB 3.49Å; L135-A351 VanDerWaalsContact CD1-CB 3.49Å
136	I	97.1	Very high	92.9	Very high	80 Å²	80	36.6 Å²	36.6	41%	0.41	20%	0.199	S	C	.	.	H	α-helix	trans	-64.4	-43.7	172.2	-68.3	165.4	0	0	0	109.9	L132 F133 W138 I139 V140 F348	L132-I136 WeakPolarHBondContact O-CG1 3.34Å; L132-I136 PolarHBondContact O-N 2.84Å; L132-I136 VanDerWaalsContact O-N 3.07Å; F133-I136 PolarHBondContact O-N 2.91Å; I136-W138 VanDerWaalsContact C-N 3.3Å; I136-W138 PolarHBondContact O-N 3.49Å; I136-I139 PolarHBondContact O-N 3.28Å; I136-I139 VanDerWaalsContact O-N 3.17Å; I136-V140 HydrophobicContact CG2-CG2 4.14Å; I136-V140 WeakPolarHBondContact O-CG2 3.38Å; I136-V140 PolarHBondContact O-N 3.37Å; I136-F348 HydrophobicContact CD1-CE2 3.75Å; I136-F348 HydrophobicContact CD1-CZ 4.22Å; I136-F348 HydrophobicContact CG1-CD2 4.09Å; I136-F348 HydrophobicContact CG1-CE2 3.62Å; I136-F348 HydrophobicContact CG1-CZ 4.38Å
137	C	96.4	Very high	93.4	Very high	22 Å²	22	38.2 Å²	38.2	15%	0.149	21%	0.207	C	C	.	.	H	α-helix	trans	-60.6	-37.7	175.7	-68.6	0	0	0	0	112.3	F133 A134 I139 S141 F268 S269	F133-C137 VanDerWaalsContact CZ-SG 3.55Å; F133-C137 PolarHBondContact O-N 3.12Å; F133-C137 PolarHBondContact O-SG 2.92Å; F133-C137 VanDerWaalsContact O-SG 3.36Å; A134-C137 PolarHBondContact O-N 2.78Å; C137-I139 PolarHBondContact O-N 3.38Å; C137-S141 WeakPolarHBondContact O-CB 3.4Å; C137-S141 PolarHBondContact O-N 3.43Å; C137-S141 PolarHBondContact O-OG 3.02Å; C137-F268 HydrophobicContact CB-CB 3.85Å; C137-S269 VanDerWaalsContact C-OG 3.22Å; C137-S269 VanDerWaalsContact CB-OG 3.29Å; C137-S269 WeakPolarHBondContact CB-OG 3.47Å
138	W	95.1	Very high	93.9	Very high	11 Å²	11	38.8 Å²	38.8	4%	0.042	21%	0.208	C	C	.	.	H	α-helix	trans	-57.5	-47.8	172.3	-90.1	116.5	0	0	0	111.9	F78 F82 R106 A134 L135 I136 S141 T142 E266 S269 F340 M344	F78-W138 AromaticContact CE1-CH2 3.8Å; F78-W138 HydrophobicContact CE1-CH2 3.8Å; F78-W138 HydrophobicContact CE1-CZ2 4.18Å; F78-W138 HydrophobicContact CE1-CZ3 4.15Å; F78-W138 HydrophobicContact CZ-CD2 4.29Å; F78-W138 AromaticContact CZ-CE2 3.83Å; F78-W138 HydrophobicContact CZ-CE3 4.34Å; F78-W138 AromaticContact CZ-CH2 3.57Å; F78-W138 HydrophobicContact CZ-CH2 3.57Å; F78-W138 AromaticContact CZ-CZ2 3.51Å; F78-W138 HydrophobicContact CZ-CZ2 3.51Å; F78-W138 AromaticContact CZ-CZ3 3.99Å; F78-W138 HydrophobicContact CZ-CZ3 3.99Å; F82-W138 HydrophobicContact CE2-CZ3 4.18Å; F82-W138 AromaticContact CZ-CZ3 3.84Å; F82-W138 HydrophobicContact CZ-CZ3 3.84Å; R106-W138 VanDerWaalsContact NH2-CZ3 3.33Å; A134-W138 PolarHBondContact O-N 2.94Å; L135-W138 WeakPolarHBondContact O-CB 3.42Å; L135-W138 PolarHBondContact O-N 3.42Å; I136-W138 VanDerWaalsContact C-N 3.3Å; I136-W138 PolarHBondContact O-N 3.49Å; W138-S141 PolarHBondContact O-OG 3.27Å; W138-T142 WeakPolarHBondContact O-CB 3.32Å; W138-T142 PolarHBondContact O-N 2.94Å; W138-T142 VanDerWaalsContact O-N 3.15Å; W138-T142 PolarHBondContact O-OG1 3.47Å; W138-E266 WeakPolarHBondContact CH2-OE1 3.26Å; W138-E266 VanDerWaalsContact CH2-OE2 3.27Å; W138-E266 WeakPolarHBondContact CH2-OE2 3.46Å; W138-E266 WeakPolarHBondContact CZ3-OE1 3.28Å; W138-S269 VanDerWaalsContact CD1-CB 3.45Å; W138-S269 PolarHBondContact N-OG 3.04Å; W138-S269 VanDerWaalsContact N-OG 3.12Å; W138-S269 VanDerWaalsContact NE1-CB 3.28Å; W138-S269 PolarHBondContact NE1-O 3.44Å; W138-F340 HydrophobicContact CB-CE1 4.48Å; W138-F340 HydrophobicContact CD2-CZ 4.47Å; W138-F340 AromaticContact CE3-CZ 3.92Å; W138-F340 HydrophobicContact CE3-CZ 3.92Å; W138-M344 HydrophobicContact CB-CE 4.29Å; W138-M344 HydrophobicContact CB-CG 4.16Å; W138-M344 HydrophobicContact CB-SD 4.46Å; W138-M344 HydrophobicContact CG-CE 4.22Å
139	I	96.5	Very high	94.1	Very high	26 Å²	26	39.6 Å²	39.6	13%	0.133	21%	0.212	C	C	.	.	H	α-helix	trans	-66	-51.9	-178.6	-63.9	164.7	0	0	0	110.3	L135 I136 C137 T142 L143 M344	L135-I139 WeakPolarHBondContact O-CG1 3.39Å; L135-I139 PolarHBondContact O-N 2.89Å; I136-I139 PolarHBondContact O-N 3.28Å; I136-I139 VanDerWaalsContact O-N 3.17Å; C137-I139 PolarHBondContact O-N 3.38Å; I139-T142 PolarHBondContact O-N 3.07Å; I139-L143 HydrophobicContact CG2-CD1 3.84Å; I139-L143 HydrophobicContact CG2-CG 4.48Å; I139-L143 WeakPolarHBondContact O-CB 3.12Å; I139-L143 WeakPolarHBondContact O-CG 2.92Å; I139-L143 PolarHBondContact O-N 3.06Å; I139-M344 HydrophobicContact CD1-CB 4.41Å; I139-M344 HydrophobicContact CD1-CG 4.14Å; I139-M344 HydrophobicContact CG1-CB 3.87Å; I139-M344 HydrophobicContact CG1-CG 3.6Å
140	V	96.6	Very high	94.2	Very high	91 Å²	91	37.5 Å²	37.5	55%	0.552	19%	0.194	S	C	*	.	H	α-helix	trans	-63.3	-46.7	-176.2	173.8	0	0	0	0	111.5	I136 T142 L143 A144	I136-V140 HydrophobicContact CG2-CG2 4.14Å; I136-V140 WeakPolarHBondContact O-CG2 3.38Å; I136-V140 PolarHBondContact O-N 3.37Å; V140-T142 VanDerWaalsContact C-N 3.3Å; V140-T142 PolarHBondContact O-N 3.26Å; V140-L143 PolarHBondContact O-N 2.88Å; V140-A144 WeakPolarHBondContact O-CB 3.41Å; V140-A144 PolarHBondContact O-N 3.2Å
141	S	94.7	Very high	94.1	Very high	9 Å²	9	41.7 Å²	41.7	6%	0.063	22%	0.22	C	C	.	.	H	α-helix	trans	-64.2	-38	179.9	59.7	0	0	0	0	111.9	C137 W138 A144 M145	C137-S141 WeakPolarHBondContact O-CB 3.4Å; C137-S141 PolarHBondContact O-N 3.43Å; C137-S141 PolarHBondContact O-OG 3.02Å; W138-S141 PolarHBondContact O-OG 3.27Å; S141-A144 PolarHBondContact O-N 3.12Å; S141-M145 WeakPolarHBondContact O-CG 2.95Å; S141-M145 PolarHBondContact O-N 3.28Å; S141-M145 VanDerWaalsContact O-N 3.16Å
142	T	94.6	Very high	94	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-72.5	-41.3	-179.1	-59.1	0	0	0	0	111.8	L81 W138 I139 V140 A144 M145 D146 F337 F340	L81-T142 HydrophobicContact CD2-CG2 3.4Å; L81-T142 VanDerWaalsContact CD2-CG2 3.4Å; W138-T142 WeakPolarHBondContact O-CB 3.32Å; W138-T142 PolarHBondContact O-N 2.94Å; W138-T142 VanDerWaalsContact O-N 3.15Å; W138-T142 PolarHBondContact O-OG1 3.47Å; I139-T142 PolarHBondContact O-N 3.07Å; V140-T142 VanDerWaalsContact C-N 3.3Å; V140-T142 PolarHBondContact O-N 3.26Å; T142-A144 VanDerWaalsContact C-N 3.32Å; T142-A144 PolarHBondContact O-N 3.44Å; T142-M145 WeakPolarHBondContact O-CB 3.48Å; T142-M145 PolarHBondContact O-N 3.07Å; T142-D146 PolarHBondContact O-N 2.97Å; T142-F337 HydrophobicContact CG2-CD1 3.7Å; T142-F337 HydrophobicContact CG2-CE1 4.22Å; T142-F337 VanDerWaalsContact O-CD1 3.29Å; T142-F337 WeakPolarHBondContact O-CD1 3.29Å; T142-F340 HydrophobicContact CG2-CB 4.32Å; T142-F340 HydrophobicContact CG2-CD1 3.44Å; T142-F340 VanDerWaalsContact CG2-CD1 3.44Å; T142-F340 HydrophobicContact CG2-CE1 3.87Å; T142-F340 HydrophobicContact CG2-CG 3.85Å; T142-F340 VanDerWaalsContact OG1-CE1 3.3Å; T142-F340 WeakPolarHBondContact OG1-CE1 3.45Å
143	L	94.3	Very high	93.6	Very high	62 Å²	62	42.6 Å²	42.6	33%	0.325	23%	0.229	S	C	.	.	H	α-helix	trans	-62.6	-40.1	171.6	-73.8	172.5	0	0	0	111.5	I139 V140 M145 D146 F147 S341	I139-L143 HydrophobicContact CG2-CD1 3.84Å; I139-L143 HydrophobicContact CG2-CG 4.48Å; I139-L143 WeakPolarHBondContact O-CB 3.12Å; I139-L143 WeakPolarHBondContact O-CG 2.92Å; I139-L143 PolarHBondContact O-N 3.06Å; V140-L143 PolarHBondContact O-N 2.88Å; L143-M145 VanDerWaalsContact C-N 3.25Å; L143-M145 PolarHBondContact O-N 3.36Å; L143-D146 WeakPolarHBondContact O-CB 3.47Å; L143-D146 PolarHBondContact O-N 3.17Å; L143-D146 VanDerWaalsContact O-N 3.11Å; L143-F147 WeakPolarHBondContact O-CD2 3.4Å; L143-F147 PolarHBondContact O-N 3.11Å; L143-S341 VanDerWaalsContact CD2-OG 3.26Å; L143-S341 WeakPolarHBondContact CD2-OG 3.34Å; L143-S341 WeakPolarHBondContact CG-OG 3.39Å
144	A	95.2	Very high	93.3	Very high	32 Å²	32	39.8 Å²	39.8	26%	0.264	22%	0.217	S	C	.	.	H	α-helix	trans	-59.4	-36.4	175.9	0	0	0	0	0	112.3	V140 S141 T142 D146 F147 I148 V261	V140-A144 WeakPolarHBondContact O-CB 3.41Å; V140-A144 PolarHBondContact O-N 3.2Å; S141-A144 PolarHBondContact O-N 3.12Å; T142-A144 VanDerWaalsContact C-N 3.32Å; T142-A144 PolarHBondContact O-N 3.44Å; A144-D146 VanDerWaalsContact C-N 3.29Å; A144-D146 PolarHBondContact O-N 3.05Å; A144-F147 PolarHBondContact O-N 2.99Å; A144-I148 VanDerWaalsContact O-CD1 3.31Å; A144-I148 WeakPolarHBondContact O-CD1 3.4Å; A144-I148 VanDerWaalsContact O-CG1 3.25Å; A144-I148 WeakPolarHBondContact O-CG1 3.22Å; A144-I148 PolarHBondContact O-N 3.44Å; A144-V261 HydrophobicContact CB-CG1 3.97Å
145	M	94	Very high	92.9	Very high	1 Å²	1	40.1 Å²	40.1	1%	0.005	22%	0.219	C	C	.	.	H	α-helix	trans	-64.6	-30.2	176.4	-66.9	174.5	-143.6	0	0	113.4	Y88 S141 T142 L143 L258 V261 I262 F337	Y88-M145 PolarHBondContact OH-O 3.38Å; S141-M145 WeakPolarHBondContact O-CG 2.95Å; S141-M145 PolarHBondContact O-N 3.28Å; S141-M145 VanDerWaalsContact O-N 3.16Å; T142-M145 WeakPolarHBondContact O-CB 3.48Å; T142-M145 PolarHBondContact O-N 3.07Å; L143-M145 VanDerWaalsContact C-N 3.25Å; L143-M145 PolarHBondContact O-N 3.36Å; M145-L258 HydrophobicContact CB-CD2 4Å; M145-L258 HydrophobicContact CG-CD2 3.97Å; M145-V261 HydrophobicContact CG-CG1 4.18Å; M145-I262 HydrophobicContact CE-CB 4.4Å; M145-I262 HydrophobicContact CE-CG1 3.57Å; M145-I262 HydrophobicContact CG-CG1 4.26Å; M145-I262 HydrophobicContact SD-CD1 4.19Å; M145-I262 HydrophobicContact SD-CG1 3.64Å; M145-F337 HydrophobicContact CB-CE1 3.84Å; M145-F337 HydrophobicContact CB-CZ 4.37Å
146	D	92.7	Very high	92.2	Very high	19 Å²	19	40.2 Å²	40.2	10%	0.102	22%	0.22	C	C	.	.	H	α-helix	trans	-71.1	-39.9	178.9	-170.2	34	0	0	0	111.8	T142 L143 A144 I148 Q149 T334 F337	T142-D146 PolarHBondContact O-N 2.97Å; L143-D146 WeakPolarHBondContact O-CB 3.47Å; L143-D146 PolarHBondContact O-N 3.17Å; L143-D146 VanDerWaalsContact O-N 3.11Å; A144-D146 VanDerWaalsContact C-N 3.29Å; A144-D146 PolarHBondContact O-N 3.05Å; D146-I148 VanDerWaalsContact C-N 3.26Å; D146-I148 PolarHBondContact O-N 3.38Å; D146-Q149 WeakPolarHBondContact O-CG 3.35Å; D146-Q149 PolarHBondContact O-NE2 3.36Å; D146-T334 WeakPolarHBondContact OD2-CG2 3.35Å; D146-F337 HydrophobicContact CB-CB 3.9Å; D146-F337 HydrophobicContact CB-CD1 3.97Å; D146-F337 HydrophobicContact CB-CD2 3.87Å; D146-F337 HydrophobicContact CB-CE1 4.48Å; D146-F337 HydrophobicContact CB-CE2 4.4Å; D146-F337 HydrophobicContact CB-CG 3.65Å; D146-F337 WeakPolarHBondContact OD1-CD2 3.45Å
147	F	92.4	Very high	91.4	Very high	170 Å²	170	38 Å²	38	75%	0.746	21%	0.21	S	C	*	.	H	α-helix	trans	-70.7	-20.8	177.5	-70.5	-71.1	0	0	0	113.7	L143 A144 Q149	L143-F147 WeakPolarHBondContact O-CD2 3.4Å; L143-F147 PolarHBondContact O-N 3.11Å; A144-F147 PolarHBondContact O-N 2.99Å; F147-Q149 PolarHBondContact O-N 3.11Å
148	I	93.4	Very high	90.2	Very high	22 Å²	22	37.1 Å²	37.1	11%	0.113	20%	0.204	C	C	.	.			trans	-86.8	94.6	-178.3	-65.1	164.3	0	0	0	109.4	A144 D146 V254 L257 L258 V261	A144-I148 VanDerWaalsContact O-CD1 3.31Å; A144-I148 WeakPolarHBondContact O-CD1 3.4Å; A144-I148 VanDerWaalsContact O-CG1 3.25Å; A144-I148 WeakPolarHBondContact O-CG1 3.22Å; A144-I148 PolarHBondContact O-N 3.44Å; D146-I148 VanDerWaalsContact C-N 3.26Å; D146-I148 PolarHBondContact O-N 3.38Å; I148-V254 HydrophobicContact CG2-CB 4.49Å; I148-V254 HydrophobicContact CG2-CG1 3.82Å; I148-V254 HydrophobicContact CG2-CG2 4.46Å; I148-L257 HydrophobicContact CB-CD2 4.31Å; I148-L257 HydrophobicContact CD1-CD2 3.79Å; I148-L257 HydrophobicContact CD1-CG 3.86Å; I148-L257 HydrophobicContact CG1-CD2 3.65Å; I148-L257 HydrophobicContact CG1-CG 4.29Å; I148-L257 HydrophobicContact CG2-CB 4.34Å; I148-L257 HydrophobicContact CG2-CD2 3.7Å; I148-L257 HydrophobicContact CG2-CG 4.25Å; I148-L258 HydrophobicContact CB-CD2 3.96Å; I148-L258 HydrophobicContact CB-CG 4.31Å; I148-L258 HydrophobicContact CD1-CD2 4.19Å; I148-L258 HydrophobicContact CG2-CD1 4.26Å; I148-L258 HydrophobicContact CG2-CD2 3.89Å; I148-L258 HydrophobicContact CG2-CG 3.67Å; I148-V261 HydrophobicContact CD1-CB 4.31Å; I148-V261 HydrophobicContact CD1-CG1 4.5Å; I148-V261 HydrophobicContact CD1-CG2 3.75Å
149	Q	91.4	Very high	88.8	Confident	90 Å²	90	41.9 Å²	41.9	42%	0.421	23%	0.23	S	C	.	.			trans	-133.1	144.8	178.3	-58.5	-176.1	23.8	0	0	111	L92 D146 F147	L92-Q149 HydrophobicContact CD2-CB 4.29Å; L92-Q149 HydrophobicContact CD2-CG 4.09Å; D146-Q149 WeakPolarHBondContact O-CG 3.35Å; D146-Q149 PolarHBondContact O-NE2 3.36Å; F147-Q149 PolarHBondContact O-N 3.11Å
150	P	91.8	Very high	87.1	Confident	11 Å²	11	42.4 Å²	42.4	7%	0.071	24%	0.242	C	C	.	.			trans	-74.8	139.3	175.6	27.4	-24.6	0	0	0	110.2	L92 A152 Y246 A250 V251 V254	L92-P150 HydrophobicContact CB-CG 4.3Å; L92-P150 WeakPolarHBondContact O-CG 3.45Å; P150-A152 PolarHBondContact O-N 2.82Å; P150-Y246 HydrophobicContact CB-CD1 3.92Å; P150-Y246 HydrophobicContact CB-CE1 4.31Å; P150-Y246 HydrophobicContact CB-CG 4.48Å; P150-Y246 HydrophobicContact CG-CD1 3.76Å; P150-Y246 HydrophobicContact CG-CE1 3.76Å; P150-Y246 HydrophobicContact CG-CG 4.24Å; P150-Y246 WeakPolarHBondContact O-CE1 3.21Å; P150-A250 HydrophobicContact CB-CB 4.38Å; P150-V251 HydrophobicContact CB-CG2 4.4Å; P150-V251 HydrophobicContact CG-CG2 4.41Å; P150-V254 HydrophobicContact CB-CG2 4Å
151	T	88.8	Confident	85.7	Confident	106 Å²	106	44.1 Å²	44.1	65%	0.65	25%	0.253	S	S	*	.			trans	-64.1	132.3	173.1	56.9	0	0	0	0	110	P153	T151-P153 WeakPolarHBondContact O-CD 3.32Å
152	A	88.6	Confident	84.5	Confident	18 Å²	18	45.3 Å²	45.3	15%	0.149	26%	0.261	C	S	.	.			trans	-99.3	90.9	175.8	0	0	0	0	0	110.4	P150 F154 A168 K244 Y246	P150-A152 PolarHBondContact O-N 2.82Å; A152-F154 VanDerWaalsContact C-N 3.29Å; A152-F154 PolarHBondContact O-N 3.09Å; A152-A168 WeakPolarHBondContact O-CB 3.39Å; A152-K244 HydrophobicContact CB-CB 3.86Å; A152-K244 HydrophobicContact CB-CD 4.07Å; A152-K244 HydrophobicContact CB-CG 3.85Å; A152-Y246 HydrophobicContact CB-CD1 3.97Å; A152-Y246 HydrophobicContact CB-CE1 3.68Å
153	P	86.7	Confident	83.6	Confident	36 Å²	36	45.8 Å²	45.8	23%	0.234	26%	0.263	C	S	.	.			trans	-71.5	-21.8	-177.5	27.2	-36.6	0	0	0	114.1	T151 A168 V245 R247	T151-P153 WeakPolarHBondContact O-CD 3.32Å; P153-A168 PolarHBondContact O-N 2.96Å; P153-V245 WeakPolarHBondContact CD-O 3.42Å; P153-R247 HydrophobicContact CG-CG 4.22Å
154	F	87.9	Confident	83	Confident	30 Å²	30	47.6 Å²	47.6	13%	0.132	27%	0.267	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-133.3	159.4	-176.2	-49.3	-74.8	0	0	0	111.5	A152 L165 I166 L233 L236 V245	A152-F154 VanDerWaalsContact C-N 3.29Å; A152-F154 PolarHBondContact O-N 3.09Å; F154-L165 HydrophobicContact CB-CD2 3.63Å; F154-L165 HydrophobicContact CG-CD2 4.16Å; F154-I166 CarbonylContact C-O 3.58Å; F154-I166 VanDerWaalsContact CA-O 3.29Å; F154-I166 WeakPolarHBondContact CA-O 3.41Å; F154-L233 HydrophobicContact CE1-CD2 4.34Å; F154-L233 HydrophobicContact CE2-CD2 4.26Å; F154-L233 HydrophobicContact CZ-CD2 3.66Å; F154-L236 HydrophobicContact CD2-CD1 3.94Å; F154-L236 HydrophobicContact CD2-CD2 4.2Å; F154-L236 HydrophobicContact CE2-CD1 4.21Å; F154-L236 HydrophobicContact CE2-CD2 4.22Å; F154-V245 HydrophobicContact CB-CB 4.09Å; F154-V245 PolarHBondContact O-N 2.99Å
155	C	86.9	Confident	82.4	Confident	7 Å²	7	46.6 Å²	46.6	5%	0.047	26%	0.257	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.6	134	172.9	-55.2	0	0	0	0	107.7	L165 I166 K243 C324	C155-L165 CarbonylContact O-C 3.53Å; C155-L165 WeakPolarHBondContact O-CA 3.25Å; C155-I166 PolarHBondContact N-O 3.01Å; C155-I166 PolarHBondContact O-N 3.35Å; C155-K243 CarbonylContact C-O 3.55Å; C155-K243 VanDerWaalsContact CA-O 3.31Å; C155-K243 WeakPolarHBondContact CA-O 3.49Å; C155-C324 HydrophobicContact CB-CB 3.61Å; C155-C324 WeakPolarHBondContact CB-SG 3.49Å; C155-C324 WeakPolarHBondContact SG-CA 3.35Å; C155-C324 WeakPolarHBondContact SG-CB 3.35Å; C155-C324 CovalentContact SG-SG 2.02Å; C155-C324 PolarHBondContact SG-SG 2.66Å
156	L	81.4	Confident	82	Confident	2 Å²	2	50.5 Å²	50.5	1%	0.01	28%	0.277	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-67	155.3	161.5	-70.9	166.6	0	0	0	108.1	Q163 Y164 L165 Y202 F203 L220 V225 S238 K243 V245	L156-Q163 HydrophobicContact CD2-CB 4.49Å; L156-Y164 CarbonylContact C-O 3.5Å; L156-Y164 WeakPolarHBondContact CA-O 3.47Å; L156-L165 HydrophobicContact CD2-CD2 4.38Å; L156-L165 HydrophobicContact CD2-CG 4.43Å; L156-Y202 VanDerWaalsContact C-CE1 3.48Å; L156-Y202 HydrophobicContact CB-CD1 3.93Å; L156-Y202 WeakPolarHBondContact O-CE1 3Å; L156-F203 HydrophobicContact CD1-CZ 4.44Å; L156-L220 HydrophobicContact CD1-CD2 4.28Å; L156-L220 HydrophobicContact CD2-CD1 4.14Å; L156-L220 HydrophobicContact CD2-CD2 4.3Å; L156-V225 HydrophobicContact CD2-CG2 3.77Å; L156-S238 VanDerWaalsContact CD1-OG 3.31Å; L156-S238 WeakPolarHBondContact CD1-OG 3.37Å; L156-K243 PolarHBondContact N-O 3.35Å; L156-V245 HydrophobicContact CB-CG2 4.48Å; L156-V245 HydrophobicContact CD1-CG2 4.06Å; L156-V245 HydrophobicContact CD2-CG2 4.19Å; L156-V245 HydrophobicContact CG-CG2 3.53Å
157	V	79.1	Confident	81.6	Confident	34 Å²	34	54.2 Å²	54.2	21%	0.206	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-149.8	129.5	164.3	-179.5	0	0	0	0	107.5	Q163 Y164 I166 Y202	V157-Q163 CarbonylContact O-C 3.57Å; V157-Y164 PolarHBondContact N-O 3.43Å; V157-Y164 PolarHBondContact O-N 3.06Å; V157-I166 HydrophobicContact CB-CD1 3.91Å; V157-I166 HydrophobicContact CB-CG1 4.41Å; V157-I166 HydrophobicContact CG1-CD1 4.48Å; V157-I166 HydrophobicContact CG2-CD1 3.46Å; V157-I166 VanDerWaalsContact CG2-CD1 3.46Å; V157-I166 HydrophobicContact CG2-CG1 4.03Å; V157-Y202 VanDerWaalsContact CA-CE1 3.4Å; V157-Y202 HydrophobicContact CB-CE1 4.33Å; V157-Y202 HydrophobicContact CG2-CE1 4.25Å
158	G	71.2	Confident	81.1	Confident	2 Å²	2	47 Å²	47	2%	0.021	27%	0.274	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.2	125	-173.7	0	0	0	0	0	113.3	G160 S162 F200	G158-G160 VanDerWaalsContact C-N 3.3Å; G158-G160 PolarHBondContact O-N 3.1Å; G158-S162 CarbonylContact C-O 3.52Å; G158-S162 WeakPolarHBondContact CA-O 3.46Å; G158-F200 WeakPolarHBondContact O-CD1 3.35Å
159	N	65.7	Low	80.1	Confident	111 Å²	111	52.3 Å²	52.3	59%	0.594	30%	0.3	S	S	*	.			trans	-89.1	42.5	-176.9	-165.4	9.1	0	0	0	113.9	T161 S162 F200	N159-T161 PolarHBondContact O-N 2.84Å; N159-S162 PolarHBondContact N-O 2.94Å; N159-F200 VanDerWaalsContact CA-CE1 3.49Å; N159-F200 HydrophobicContact CB-CD1 4.44Å; N159-F200 HydrophobicContact CB-CE1 3.78Å
160	G	61.9	Low	78.6	Confident	37 Å²	37	56.7 Å²	56.7	38%	0.381	32%	0.321	S	S	.	.	S	Bend	trans	72.4	-31.9	-178.4	0	0	0	0	0	115.8	G158	G158-G160 VanDerWaalsContact C-N 3.3Å; G158-G160 PolarHBondContact O-N 3.1Å
161	T	67.3	Low	76.6	Confident	128 Å²	128	59.7 Å²	59.7	79%	0.785	35%	0.353	S	S	*	.	S	Bend	trans	-114.5	-22.4	-178.7	56	0	0	0	0	114.3	N159	N159-T161 PolarHBondContact O-N 2.84Å
162	S	68.3	Low	74.3	Confident	33 Å²	33	62.6 Å²	62.6	23%	0.231	37%	0.365	C	S	.	.			trans	-147.8	146.6	-176.8	-67.5	0	0	0	0	110.9	G158 N159 N226	G158-S162 CarbonylContact C-O 3.52Å; G158-S162 WeakPolarHBondContact CA-O 3.46Å; N159-S162 PolarHBondContact N-O 2.94Å; S162-N226 WeakPolarHBondContact CB-ND2 3.46Å; S162-N226 PolarHBondContact OG-ND2 3.4Å
163	Q	76.5	Confident	71.7	Confident	10 Å²	10	65 Å²	65	5%	0.047	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.7	147.3	173.1	-59.6	179.2	-4.5	0	0	110.9	L156 V157 Y202 V224 V225 N226	L156-Q163 HydrophobicContact CD2-CB 4.49Å; V157-Q163 CarbonylContact O-C 3.57Å; Q163-Y202 PolarHBondContact NE2-O 3.36Å; Q163-V224 WeakPolarHBondContact CB-O 3.45Å; Q163-V224 VanDerWaalsContact OE1-CG1 3.32Å; Q163-V225 HydrophobicContact CB-CG2 4.08Å; Q163-V225 WeakPolarHBondContact O-CA 3.38Å; Q163-N226 PolarHBondContact O-N 3.01Å
164	Y	81.1	Confident	69.4	Low	101 Å²	101	70.7 Å²	70.7	40%	0.396	42%	0.419	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.9	145.8	177.1	-59.6	-87.9	0	0	0	109.7	L156 V157 N226 N227	L156-Y164 CarbonylContact C-O 3.5Å; L156-Y164 WeakPolarHBondContact CA-O 3.47Å; V157-Y164 PolarHBondContact N-O 3.43Å; V157-Y164 PolarHBondContact O-N 3.06Å; Y164-N226 HydrophobicContact CD1-CB 4.22Å; Y164-N226 HydrophobicContact CE1-CB 3.8Å; Y164-N226 PolarHBondContact OH-ND2 2.9Å; Y164-N227 WeakPolarHBondContact CA-OD1 3.45Å; Y164-N227 HydrophobicContact CD1-CB 4.49Å
165	L	83.9	Confident	66.8	Low	11 Å²	11	74.5 Å²	74.5	6%	0.058	44%	0.441	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.1	131.3	168.9	-74.6	144.7	0	0	0	109.9	F154 C155 L156 L220 V225 N227 Y228 L233 L236 V245	F154-L165 HydrophobicContact CB-CD2 3.63Å; F154-L165 HydrophobicContact CG-CD2 4.16Å; C155-L165 CarbonylContact O-C 3.53Å; C155-L165 WeakPolarHBondContact O-CA 3.25Å; L156-L165 HydrophobicContact CD2-CD2 4.38Å; L156-L165 HydrophobicContact CD2-CG 4.43Å; L165-L220 HydrophobicContact CD2-CD1 4.2Å; L165-V225 HydrophobicContact CB-CG1 4.49Å; L165-V225 HydrophobicContact CD1-CG1 3.59Å; L165-V225 HydrophobicContact CG-CG1 3.76Å; L165-N227 PolarHBondContact N-ND2 3.43Å; L165-N227 PolarHBondContact N-OD1 3.22Å; L165-N227 PolarHBondContact O-ND2 2.95Å; L165-Y228 HydrophobicContact CD1-CD2 3.84Å; L165-Y228 HydrophobicContact CD1-CG 4.11Å; L165-L233 HydrophobicContact CD1-CD1 4.44Å; L165-L236 HydrophobicContact CD1-CD1 4.12Å; L165-L236 HydrophobicContact CD2-CD1 4.03Å; L165-V245 HydrophobicContact CD2-CB 4.16Å; L165-V245 HydrophobicContact CD2-CG1 4Å; L165-V245 HydrophobicContact CD2-CG2 3.9Å
166	I	84.5	Confident	64.5	Low	83 Å²	83	79.6 Å²	79.6	43%	0.426	48%	0.477	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.5	142.8	171.8	-52.3	-174.2	0	0	0	107.8	F154 C155 V157	F154-I166 CarbonylContact C-O 3.58Å; F154-I166 VanDerWaalsContact CA-O 3.29Å; F154-I166 WeakPolarHBondContact CA-O 3.41Å; C155-I166 PolarHBondContact N-O 3.01Å; C155-I166 PolarHBondContact O-N 3.35Å; V157-I166 HydrophobicContact CB-CD1 3.91Å; V157-I166 HydrophobicContact CB-CG1 4.41Å; V157-I166 HydrophobicContact CG1-CD1 4.48Å; V157-I166 HydrophobicContact CG2-CD1 3.46Å; V157-I166 VanDerWaalsContact CG2-CD1 3.46Å; V157-I166 HydrophobicContact CG2-CG1 4.03Å
167	P	84.9	Confident	62.4	Low	96 Å²	96	83.2 Å²	83.2	62%	0.623	50%	0.502	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-55.5	140.8	170.8	-24.1	34.4	0	0	0	111.7
168	A	81.7	Confident	60.5	Low	20 Å²	20	88 Å²	88	17%	0.165	52%	0.52	C	S	.	.	P	Polyproline II helix	trans	-64.1	146.3	169.9	0	0	0	0	0	110.7	A152 P153 E170 P323	A152-A168 WeakPolarHBondContact O-CB 3.39Å; P153-A168 PolarHBondContact O-N 2.96Å; A168-E170 PolarHBondContact O-N 3.34Å; A168-P323 HydrophobicContact CB-CB 3.87Å
169	M	72.4	Confident	59.1	Low	133 Å²	133	89.5 Å²	89.5	66%	0.655	54%	0.536	S	S	*	.	P	Polyproline II helix	trans	-66.9	117.1	171.4	-67.7	-166.9	-89.6	0	0	109.1	G171 P323	M169-G171 PolarHBondContact O-N 3.24Å; M169-P323 PolarHBondContact N-O 3.42Å
170	E	58.8	Low	57.8	Low	182 Å²	182	91.1 Å²	91.1	85%	0.85	54%	0.544	S	S	*	.	P	Polyproline II helix	trans	-62.9	128.8	172.2	-78.9	179.9	165.1	0	0	109.2	A168 D172	A168-E170 PolarHBondContact O-N 3.34Å; E170-D172 PolarHBondContact O-N 3.44Å
171	G	51.3	Low	56.6	Low	74 Å²	74	97.1 Å²	97.1	76%	0.763	56%	0.562	S	S	*	*	S	Bend	trans	-68.2	8.3	-173.1	0	0	0	0	0	115.9	M169	M169-G171 PolarHBondContact O-N 3.24Å
172	D	39.3	Very low	55.4	Low	167 Å²	167	93.7 Å²	93.7	89%	0.893	55%	0.547	S	S	*	.	S	Bend	trans	-110.8	65	-172.6	-70.3	-21.6	0	0	0	111.5	E170	E170-D172 PolarHBondContact O-N 3.44Å
173	G	35.5	Very low	54.4	Low	69 Å²	69	98 Å²	98	71%	0.711	57%	0.567	S	S	*	*	S	Bend	trans	-171	-9.4	176.8	0	0	0	0	0	118.5
174	L	36.7	Very low	53.2	Low	154 Å²	154	101.5 Å²	101.5	81%	0.806	59%	0.586	S	S	*	*	S	Bend	trans	-118.5	100	176.3	-131	80.4	0	0	0	110.8	S176	L174-S176 PolarHBondContact O-N 3.22Å; L174-S176 VanDerWaalsContact O-N 3.16Å
175	D	33.4	Very low	52	Low	110 Å²	110	101.8 Å²	101.8	59%	0.588	60%	0.598	S	S	*	*			trans	-21.7	109.4	167.4	-147.2	-6.8	0	0	0	112.8	S177 K178	D175-S177 PolarHBondContact O-N 3.18Å; D175-K178 PolarHBondContact O-N 3.02Å
176	S	38.6	Very low	50.7	Low	114 Å²	114	105 Å²	105	80%	0.797	62%	0.621	S	S	*	*	H	α-helix	trans	-55.7	-17.2	-179.5	-168.6	0	0	0	0	112.5	L174 K178	L174-S176 PolarHBondContact O-N 3.22Å; L174-S176 VanDerWaalsContact O-N 3.16Å; S176-K178 VanDerWaalsContact C-N 3.35Å; S176-K178 PolarHBondContact O-N 3.27Å
177	S	39	Very low	49.5	Very low	79 Å²	79	107.4 Å²	107.4	55%	0.552	63%	0.629	S	S	*	*	H	α-helix	trans	-70.3	-19.7	171.3	-172.1	0	0	0	0	114.9	D175	D175-S177 PolarHBondContact O-N 3.18Å
178	K	38.7	Very low	47.9	Very low	133 Å²	133	105.3 Å²	105.3	58%	0.578	61%	0.611	S	S	*	*	H	α-helix	trans	-94	-21.6	179.1	-73.3	-175.7	178.3	176.5	0	113.7	D175 S176 L180 Q181 A182	D175-K178 PolarHBondContact O-N 3.02Å; S176-K178 VanDerWaalsContact C-N 3.35Å; S176-K178 PolarHBondContact O-N 3.27Å; K178-L180 VanDerWaalsContact C-N 3.27Å; K178-L180 PolarHBondContact O-N 2.95Å; K178-Q181 PolarHBondContact O-N 2.95Å; K178-A182 PolarHBondContact O-N 3.23Å
179	G	41.2	Very low	46.6	Very low	35 Å²	35	110.3 Å²	110.3	36%	0.361	63%	0.629	S	S	.	*	H	α-helix	trans	-66.7	-26	176	0	0	0	0	0	113.8
180	L	39.5	Very low	45.8	Very low	145 Å²	145	106.2 Å²	106.2	76%	0.759	62%	0.617	S	S	*	*	S	Bend	trans	-83.7	-20.5	175.4	-131.5	83	0	0	0	113.3	K178 A182	K178-L180 VanDerWaalsContact C-N 3.27Å; K178-L180 PolarHBondContact O-N 2.95Å; L180-A182 VanDerWaalsContact C-N 3.33Å
181	Q	37	Very low	45.6	Very low	162 Å²	162	101.5 Å²	101.5	76%	0.757	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.6	-0.1	175.8	-73.6	-177.1	-8.7	0	0	113.2	K178	K178-Q181 PolarHBondContact O-N 2.95Å
182	A	42	Very low	45.5	Very low	57 Å²	57	103.9 Å²	103.9	47%	0.471	58%	0.584	S	S	.	*	T	Hydrogen-bonded Turn	trans	-99.4	12.9	178.8	0	0	0	0	0	114.2	K178 L180 D184	K178-A182 PolarHBondContact O-N 3.23Å; L180-A182 VanDerWaalsContact C-N 3.33Å; A182-D184 PolarHBondContact O-N 3.3Å
183	L	47.2	Very low	46.1	Very low	124 Å²	124	100.5 Å²	100.5	65%	0.649	56%	0.563	S	S	*	*			trans	-79.8	47.6	169.8	-90.9	152.8	0	0	0	111.5	V185	L183-V185 PolarHBondContact O-N 3.29Å
184	D	50.5	Low	46.8	Very low	82 Å²	82	99.7 Å²	99.7	44%	0.439	55%	0.55	S	S	.	.			trans	-89.7	92.5	162.6	-169.1	-8.4	0	0	0	108.1	A182 S186 K187 M188	A182-D184 PolarHBondContact O-N 3.3Å; D184-S186 PolarHBondContact O-N 2.85Å; D184-S186 VanDerWaalsContact O-N 3.11Å; D184-S186 WeakPolarHBondContact OD1-CB 3.31Å; D184-S186 PolarHBondContact OD1-N 2.86Å; D184-S186 VanDerWaalsContact OD1-N 3.09Å; D184-S186 PolarHBondContact OD1-OG 3.42Å; D184-S186 PolarHBondContact OD2-OG 2.99Å; D184-K187 HydrophobicContact CB-CB 3.97Å; D184-K187 PolarHBondContact O-N 3Å; D184-M188 PolarHBondContact O-N 3.4Å
185	V	56	Low	47.5	Very low	107 Å²	107	97.3 Å²	97.3	65%	0.648	53%	0.534	S	S	*	.	H	α-helix	trans	-53.5	-31.3	178.5	-179.9	0	0	0	0	110.9	L183 K189	L183-V185 PolarHBondContact O-N 3.29Å; V185-K189 VanDerWaalsContact O-CB 3.23Å; V185-K189 WeakPolarHBondContact O-CB 3.49Å; V185-K189 PolarHBondContact O-N 3.33Å
186	S	56.5	Low	48	Very low	79 Å²	79	95 Å²	95	55%	0.552	53%	0.526	S	S	*	.	H	α-helix	trans	-72.7	-39.7	179.6	71.6	0	0	0	0	112.3	D184 K189 A190	D184-S186 PolarHBondContact O-N 2.85Å; D184-S186 VanDerWaalsContact O-N 3.11Å; D184-S186 WeakPolarHBondContact OD1-CB 3.31Å; D184-S186 PolarHBondContact OD1-N 2.86Å; D184-S186 VanDerWaalsContact OD1-N 3.09Å; D184-S186 PolarHBondContact OD1-OG 3.42Å; D184-S186 PolarHBondContact OD2-OG 2.99Å; S186-K189 PolarHBondContact O-N 3.07Å; S186-A190 WeakPolarHBondContact O-CB 3.38Å; S186-A190 PolarHBondContact O-N 3.25Å
187	K	58.5	Low	48.2	Very low	133 Å²	133	97.7 Å²	97.7	58%	0.578	53%	0.527	S	S	*	.	H	α-helix	trans	-68.6	-40.9	172.8	-168.8	177.2	179.9	-179.8	0	112	D184 K189 A190 D191	D184-K187 HydrophobicContact CB-CB 3.97Å; D184-K187 PolarHBondContact O-N 3Å; K187-K189 VanDerWaalsContact C-N 3.29Å; K187-K189 PolarHBondContact O-N 3.04Å; K187-A190 CarbonylContact O-C 3.57Å; K187-A190 WeakPolarHBondContact O-CB 3.12Å; K187-A190 PolarHBondContact O-N 3.33Å; K187-A190 VanDerWaalsContact O-N 3.17Å; K187-D191 WeakPolarHBondContact O-CB 3.17Å; K187-D191 VanDerWaalsContact O-CG 3.3Å; K187-D191 PolarHBondContact O-N 3.23Å
188	M	51.1	Low	48.1	Very low	53 Å²	53	99.2 Å²	99.2	26%	0.261	53%	0.528	S	S	.	.	H	α-helix	trans	-63.3	-35.7	172.7	-95.9	-178.6	166.2	0	0	112.7	D184 Y192 V318	D184-M188 PolarHBondContact O-N 3.4Å; M188-Y192 VanDerWaalsContact O-CB 3.23Å; M188-Y192 WeakPolarHBondContact O-CB 3.33Å; M188-Y192 PolarHBondContact O-N 2.81Å; M188-V318 HydrophobicContact CE-CB 4.32Å; M188-V318 HydrophobicContact CE-CG1 3.44Å; M188-V318 VanDerWaalsContact CE-CG1 3.44Å; M188-V318 HydrophobicContact CE-CG2 3.9Å; M188-V318 HydrophobicContact SD-CG1 4.13Å; M188-V318 HydrophobicContact SD-CG2 3.62Å
189	K	56.1	Low	48.2	Very low	124 Å²	124	99.1 Å²	99.1	54%	0.539	53%	0.528	S	S	.	.	H	α-helix	trans	-69.2	-38	173.4	-167.8	-177.5	-178.3	-160.1	0	111.2	V185 S186 K187 Y192 E193	V185-K189 VanDerWaalsContact O-CB 3.23Å; V185-K189 WeakPolarHBondContact O-CB 3.49Å; V185-K189 PolarHBondContact O-N 3.33Å; S186-K189 PolarHBondContact O-N 3.07Å; K187-K189 VanDerWaalsContact C-N 3.29Å; K187-K189 PolarHBondContact O-N 3.04Å; K189-Y192 CarbonylContact O-C 3.4Å; K189-Y192 WeakPolarHBondContact O-CB 3.47Å; K189-Y192 PolarHBondContact O-N 3.39Å; K189-E193 WeakPolarHBondContact CE-OE1 3.46Å; K189-E193 IonicContact NZ-OE1 3.04Å; K189-E193 WeakPolarHBondContact O-CB 3.43Å; K189-E193 VanDerWaalsContact O-CG 3.28Å; K189-E193 WeakPolarHBondContact O-CG 3.39Å; K189-E193 PolarHBondContact O-N 2.93Å
190	A	55.8	Low	48.2	Very low	48 Å²	48	101.8 Å²	101.8	40%	0.397	53%	0.53	S	S	.	.	H	α-helix	trans	-66.6	-39.9	173.4	0	0	0	0	0	111.9	S186 K187 Y192 E193 A194	S186-A190 WeakPolarHBondContact O-CB 3.38Å; S186-A190 PolarHBondContact O-N 3.25Å; K187-A190 CarbonylContact O-C 3.57Å; K187-A190 WeakPolarHBondContact O-CB 3.12Å; K187-A190 PolarHBondContact O-N 3.33Å; K187-A190 VanDerWaalsContact O-N 3.17Å; A190-Y192 VanDerWaalsContact C-N 3.35Å; A190-E193 PolarHBondContact O-N 2.57Å; A190-A194 WeakPolarHBondContact O-CB 3.42Å; A190-A194 PolarHBondContact O-N 2.79Å
191	D	53.3	Low	48.4	Very low	82 Å²	82	96.2 Å²	96.2	44%	0.439	50%	0.503	S	S	.	.	H	α-helix	trans	-66.8	-37.7	173	-68.9	-20.3	0	0	0	110.5	K187 A194 E195	K187-D191 WeakPolarHBondContact O-CB 3.17Å; K187-D191 VanDerWaalsContact O-CG 3.3Å; K187-D191 PolarHBondContact O-N 3.23Å; D191-A194 PolarHBondContact O-N 3.26Å; D191-E195 WeakPolarHBondContact O-CB 3.16Å; D191-E195 WeakPolarHBondContact O-CG 3.36Å; D191-E195 PolarHBondContact O-N 3.03Å
192	Y	50.4	Low	49.3	Very low	125 Å²	125	90.7 Å²	90.7	49%	0.49	48%	0.476	S	S	.	.	H	α-helix	trans	-63	-44.5	171.1	173.6	-93.1	0	0	0	111.5	M188 K189 A190 S196 V328	M188-Y192 VanDerWaalsContact O-CB 3.23Å; M188-Y192 WeakPolarHBondContact O-CB 3.33Å; M188-Y192 PolarHBondContact O-N 2.81Å; K189-Y192 CarbonylContact O-C 3.4Å; K189-Y192 WeakPolarHBondContact O-CB 3.47Å; K189-Y192 PolarHBondContact O-N 3.39Å; A190-Y192 VanDerWaalsContact C-N 3.35Å; Y192-S196 WeakPolarHBondContact O-CA 3.38Å; Y192-S196 WeakPolarHBondContact O-CB 3.36Å; Y192-S196 PolarHBondContact O-N 2.94Å; Y192-S196 PolarHBondContact O-OG 2.85Å; Y192-V328 HydrophobicContact CD2-CG2 4.13Å; Y192-V328 HydrophobicContact CE2-CG1 4.48Å; Y192-V328 HydrophobicContact CE2-CG2 4.13Å
193	E	51.5	Low	50	Low	96 Å²	96	88.7 Å²	88.7	45%	0.449	46%	0.456	S	S	.	.	H	α-helix	trans	-67	-42.3	177.8	-75.5	170.2	-175	0	0	110.3	K189 A190 S196 E197	K189-E193 WeakPolarHBondContact CE-OE1 3.46Å; K189-E193 IonicContact NZ-OE1 3.04Å; K189-E193 WeakPolarHBondContact O-CB 3.43Å; K189-E193 VanDerWaalsContact O-CG 3.28Å; K189-E193 WeakPolarHBondContact O-CG 3.39Å; K189-E193 PolarHBondContact O-N 2.93Å; A190-E193 PolarHBondContact O-N 2.57Å; E193-S196 WeakPolarHBondContact CA-OG 3.14Å; E193-S196 PolarHBondContact O-N 3.36Å; E193-S196 PolarHBondContact O-OG 3.32Å; E193-E197 PolarHBondContact O-N 2.93Å
194	A	50.9	Low	50.6	Low	52 Å²	52	83.9 Å²	83.9	43%	0.43	43%	0.433	S	S	.	.	H	α-helix	trans	-70.9	-36.4	177.7	0	0	0	0	0	113.7	A190 D191	A190-A194 WeakPolarHBondContact O-CB 3.42Å; A190-A194 PolarHBondContact O-N 2.79Å; D191-A194 PolarHBondContact O-N 3.26Å
195	E	50.1	Low	51	Low	103 Å²	103	85.7 Å²	85.7	48%	0.481	44%	0.439	S	S	.	.	H	α-helix	trans	-75	-25.8	169.2	-77.1	-169.1	157.9	0	0	111.5	D191 N198	D191-E195 WeakPolarHBondContact O-CB 3.16Å; D191-E195 WeakPolarHBondContact O-CG 3.36Å; D191-E195 PolarHBondContact O-N 3.03Å; E195-N198 CarbonylContact O-C 3.45Å; E195-N198 PolarHBondContact O-N 3.17Å
196	S	45.2	Very low	51.3	Low	61 Å²	61	88.5 Å²	88.5	43%	0.427	44%	0.438	S	S	.	.	H	α-helix	trans	-73.7	-30.1	174.8	79.4	0	0	0	0	112.7	Y192 E193 N198	Y192-S196 WeakPolarHBondContact O-CA 3.38Å; Y192-S196 WeakPolarHBondContact O-CB 3.36Å; Y192-S196 PolarHBondContact O-N 2.94Å; Y192-S196 PolarHBondContact O-OG 2.85Å; E193-S196 WeakPolarHBondContact CA-OG 3.14Å; E193-S196 PolarHBondContact O-N 3.36Å; E193-S196 PolarHBondContact O-OG 3.32Å; S196-N198 VanDerWaalsContact C-N 3.33Å
197	E	41.5	Very low	51.6	Low	172 Å²	172	86.1 Å²	86.1	80%	0.804	42%	0.417	S	S	*	.	H	α-helix	trans	-73.1	-24.4	173.7	-77.4	-166.9	156.9	0	0	112.6	E193	E193-E197 PolarHBondContact O-N 2.93Å
198	N	37.9	Very low	51.9	Low	110 Å²	110	83.3 Å²	83.3	59%	0.588	41%	0.407	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.1	81.5	168.9	-71.1	-50	0	0	0	110.2	E195 S196 F200	E195-N198 CarbonylContact O-C 3.45Å; E195-N198 PolarHBondContact O-N 3.17Å; S196-N198 VanDerWaalsContact C-N 3.33Å; N198-F200 VanDerWaalsContact C-N 3.26Å; N198-F200 PolarHBondContact O-N 3.4Å
199	F	39.4	Very low	52.5	Low	131 Å²	131	88.7 Å²	88.7	58%	0.575	43%	0.428	S	S	*	.	T	Hydrogen-bonded Turn	trans	-56.2	74.7	-174.8	-157.4	-92.9	0	0	0	114	S201	F199-S201 PolarHBondContact O-N 3.17Å; F199-S201 VanDerWaalsContact O-N 3.13Å
200	F	41	Very low	53.1	Low	91 Å²	91	87.9 Å²	87.9	40%	0.399	43%	0.434	S	S	.	.			trans	-85	70	166.3	-69.2	-39.2	0	0	0	108.4	G158 N159 N198 Y202	G158-F200 WeakPolarHBondContact O-CD1 3.35Å; N159-F200 VanDerWaalsContact CA-CE1 3.49Å; N159-F200 HydrophobicContact CB-CD1 4.44Å; N159-F200 HydrophobicContact CB-CE1 3.78Å; N198-F200 VanDerWaalsContact C-N 3.26Å; N198-F200 PolarHBondContact O-N 3.4Å; F200-Y202 HydrophobicContact CB-CE2 4.39Å; F200-Y202 VanDerWaalsContact O-CD2 3.3Å; F200-Y202 WeakPolarHBondContact O-CD2 3.01Å; F200-Y202 WeakPolarHBondContact O-CE2 3.33Å; F200-Y202 PolarHBondContact O-N 3.34Å; F200-Y202 VanDerWaalsContact O-N 3.13Å
201	S	45.2	Very low	54.1	Low	28 Å²	28	87 Å²	87	20%	0.196	42%	0.421	C	S	.	.			trans	-66.7	108.3	157.9	68.7	0	0	0	0	106.8	F199 F203	F199-S201 PolarHBondContact O-N 3.17Å; F199-S201 VanDerWaalsContact O-N 3.13Å; S201-F203 VanDerWaalsContact CB-O 3.31Å; S201-F203 WeakPolarHBondContact CB-O 3.12Å; S201-F203 CarbonylContact O-C 3.59Å; S201-F203 PolarHBondContact O-N 3.21Å; S201-F203 PolarHBondContact OG-O 3.37Å
202	Y	55.2	Low	55.7	Low	46 Å²	46	86.4 Å²	86.4	18%	0.18	42%	0.42	C	S	.	.	S	Bend	trans	-55.8	-40.1	-176.8	-75.5	-97.3	0	0	0	110.7	L156 V157 Q163 F200 K243	L156-Y202 VanDerWaalsContact C-CE1 3.48Å; L156-Y202 HydrophobicContact CB-CD1 3.93Å; L156-Y202 WeakPolarHBondContact O-CE1 3Å; V157-Y202 VanDerWaalsContact CA-CE1 3.4Å; V157-Y202 HydrophobicContact CB-CE1 4.33Å; V157-Y202 HydrophobicContact CG2-CE1 4.25Å; Q163-Y202 PolarHBondContact NE2-O 3.36Å; F200-Y202 HydrophobicContact CB-CE2 4.39Å; F200-Y202 VanDerWaalsContact O-CD2 3.3Å; F200-Y202 WeakPolarHBondContact O-CD2 3.01Å; F200-Y202 WeakPolarHBondContact O-CE2 3.33Å; F200-Y202 PolarHBondContact O-N 3.34Å; F200-Y202 VanDerWaalsContact O-N 3.13Å; Y202-K243 HydrophobicContact CD1-CG 3.96Å; Y202-K243 HydrophobicContact CD2-CD 4.39Å; Y202-K243 HydrophobicContact CD2-CG 4.07Å; Y202-K243 HydrophobicContact CE1-CB 4.26Å; Y202-K243 HydrophobicContact CE1-CD 3.74Å; Y202-K243 HydrophobicContact CE1-CG 3.65Å; Y202-K243 HydrophobicContact CE2-CD 3.68Å; Y202-K243 HydrophobicContact CE2-CG 3.87Å; Y202-K243 HydrophobicContact CG-CG 4.16Å; Y202-K243 VanDerWaalsContact OH-CD 3.27Å; Y202-K243 WeakPolarHBondContact OH-CD 3.41Å; Y202-K243 WeakPolarHBondContact OH-CE 3.43Å; Y202-K243 PolarHBondContact OH-NZ 3.45Å
203	F	56.9	Low	57.5	Low	15 Å²	15	80.7 Å²	80.7	7%	0.066	40%	0.398	C	S	.	.	S	Bend	trans	-107	130.4	161.6	-68.8	-75.4	0	0	0	109.7	L156 S201 Y207	L156-F203 HydrophobicContact CD1-CZ 4.44Å; S201-F203 VanDerWaalsContact CB-O 3.31Å; S201-F203 WeakPolarHBondContact CB-O 3.12Å; S201-F203 CarbonylContact O-C 3.59Å; S201-F203 PolarHBondContact O-N 3.21Å; S201-F203 PolarHBondContact OG-O 3.37Å; F203-Y207 HydrophobicContact CB-CD1 3.48Å; F203-Y207 VanDerWaalsContact CB-CD1 3.48Å; F203-Y207 HydrophobicContact CB-CE1 4.13Å; F203-Y207 HydrophobicContact CB-CG 4.06Å; F203-Y207 AromaticContact CD1-CD1 3.38Å; F203-Y207 HydrophobicContact CD1-CD1 3.38Å; F203-Y207 HydrophobicContact CD1-CD2 4.12Å; F203-Y207 AromaticContact CD1-CE1 3.36Å; F203-Y207 HydrophobicContact CD1-CE1 3.36Å; F203-Y207 HydrophobicContact CD1-CE2 4.13Å; F203-Y207 AromaticContact CD1-CG 3.77Å; F203-Y207 HydrophobicContact CD1-CG 3.77Å; F203-Y207 AromaticContact CD1-CZ 3.76Å; F203-Y207 HydrophobicContact CD2-CD1 4.49Å; F203-Y207 HydrophobicContact CD2-CE1 4.31Å; F203-Y207 HydrophobicContact CE1-CD1 4.26Å; F203-Y207 AromaticContact CE1-CE1 3.79Å; F203-Y207 HydrophobicContact CE1-CE1 3.79Å; F203-Y207 HydrophobicContact CE1-CE2 4.29Å; F203-Y207 AromaticContact CE1-CZ 3.82Å; F203-Y207 AromaticContact CG-CD1 3.53Å; F203-Y207 HydrophobicContact CG-CD1 3.53Å; F203-Y207 AromaticContact CG-CE1 3.66Å; F203-Y207 HydrophobicContact CG-CE1 3.66Å; F203-Y207 HydrophobicContact CG-CG 4.24Å; F203-Y207 HydrophobicContact CZ-CE1 4.43Å
204	P	58.8	Low	59.4	Low	23 Å²	23	76.1 Å²	76.1	15%	0.149	38%	0.377	C	S	.	.			trans	-55.1	151.7	173.8	-25.5	34.2	0	0	0	112.1	W206 Y207 M208	P204-W206 HydrophobicContact CB-CD2 4.35Å; P204-W206 HydrophobicContact CB-CG 4.01Å; P204-W206 HydrophobicContact CG-CZ2 4.24Å; P204-W206 PolarHBondContact O-N 2.97Å; P204-W206 VanDerWaalsContact O-N 3.1Å; P204-Y207 WeakPolarHBondContact O-CA 3.47Å; P204-Y207 VanDerWaalsContact O-CB 3.29Å; P204-Y207 WeakPolarHBondContact O-CB 3.17Å; P204-Y207 PolarHBondContact O-N 3.38Å; P204-M208 PolarHBondContact O-N 3.37Å
205	E	59.8	Low	61.3	Low	121 Å²	121	76.2 Å²	76.2	57%	0.565	37%	0.37	S	S	*	.	H	α-helix	trans	-53.7	-35.8	176.9	-74.3	-165.9	172.4	0	0	113.4	Y207 M208 K209	E205-Y207 PolarHBondContact O-N 2.9Å; E205-M208 PolarHBondContact O-N 3Å; E205-K209 WeakPolarHBondContact O-CG 3.43Å; E205-K209 PolarHBondContact O-N 3.22Å; E205-K209 IonicContact OE2-NZ 3.98Å
206	W	63	Low	63.2	Low	165 Å²	165	71.6 Å²	71.6	63%	0.625	35%	0.349	S	S	*	.	H	α-helix	trans	-62	-36.1	177	69.5	-103.4	0	0	0	111.5	P204 K209 V210	P204-W206 HydrophobicContact CB-CD2 4.35Å; P204-W206 HydrophobicContact CB-CG 4.01Å; P204-W206 HydrophobicContact CG-CZ2 4.24Å; P204-W206 PolarHBondContact O-N 2.97Å; P204-W206 VanDerWaalsContact O-N 3.1Å; W206-K209 PolarHBondContact O-N 3.18Å; W206-V210 VanDerWaalsContact O-CG2 3.29Å; W206-V210 WeakPolarHBondContact O-CG2 3.4Å; W206-V210 PolarHBondContact O-N 3.29Å
207	Y	63.1	Low	65.4	Low	29 Å²	29	69.6 Å²	69.6	11%	0.114	33%	0.334	C	S	.	.	H	α-helix	trans	-66.6	-43.4	178.1	177.9	-85.6	0	0	0	110.2	F203 P204 E205 K209 V210 K211 E218	F203-Y207 HydrophobicContact CB-CD1 3.48Å; F203-Y207 VanDerWaalsContact CB-CD1 3.48Å; F203-Y207 HydrophobicContact CB-CE1 4.13Å; F203-Y207 HydrophobicContact CB-CG 4.06Å; F203-Y207 AromaticContact CD1-CD1 3.38Å; F203-Y207 HydrophobicContact CD1-CD1 3.38Å; F203-Y207 HydrophobicContact CD1-CD2 4.12Å; F203-Y207 AromaticContact CD1-CE1 3.36Å; F203-Y207 HydrophobicContact CD1-CE1 3.36Å; F203-Y207 HydrophobicContact CD1-CE2 4.13Å; F203-Y207 AromaticContact CD1-CG 3.77Å; F203-Y207 HydrophobicContact CD1-CG 3.77Å; F203-Y207 AromaticContact CD1-CZ 3.76Å; F203-Y207 HydrophobicContact CD2-CD1 4.49Å; F203-Y207 HydrophobicContact CD2-CE1 4.31Å; F203-Y207 HydrophobicContact CE1-CD1 4.26Å; F203-Y207 AromaticContact CE1-CE1 3.79Å; F203-Y207 HydrophobicContact CE1-CE1 3.79Å; F203-Y207 HydrophobicContact CE1-CE2 4.29Å; F203-Y207 AromaticContact CE1-CZ 3.82Å; F203-Y207 AromaticContact CG-CD1 3.53Å; F203-Y207 HydrophobicContact CG-CD1 3.53Å; F203-Y207 AromaticContact CG-CE1 3.66Å; F203-Y207 HydrophobicContact CG-CE1 3.66Å; F203-Y207 HydrophobicContact CG-CG 4.24Å; F203-Y207 HydrophobicContact CZ-CE1 4.43Å; P204-Y207 WeakPolarHBondContact O-CA 3.47Å; P204-Y207 VanDerWaalsContact O-CB 3.29Å; P204-Y207 WeakPolarHBondContact O-CB 3.17Å; P204-Y207 PolarHBondContact O-N 3.38Å; E205-Y207 PolarHBondContact O-N 2.9Å; Y207-K209 VanDerWaalsContact C-N 3.25Å; Y207-K209 PolarHBondContact O-N 3.46Å; Y207-V210 PolarHBondContact O-N 2.8Å; Y207-V210 VanDerWaalsContact O-N 3.15Å; Y207-K211 HydrophobicContact CE1-CB 4.39Å; Y207-K211 HydrophobicContact CE1-CD 4.06Å; Y207-K211 HydrophobicContact CE1-CG 4.49Å; Y207-K211 WeakPolarHBondContact O-CB 3.17Å; Y207-K211 PolarHBondContact O-N 3.16Å; Y207-K211 PolarHBondContact OH-NZ 2.91Å; Y207-E218 WeakPolarHBondContact OH-CG 3.27Å; Y207-E218 PolarHBondContact OH-OE1 3.23Å; Y207-E218 PolarHBondContact OH-OE2 3.27Å
208	M	64.4	Low	67.5	Low	74 Å²	74	63.6 Å²	63.6	37%	0.365	31%	0.306	S	S	.	.	H	α-helix	trans	-62.3	-32.4	175.1	-67.4	-62.2	-127.9	0	0	112.6	P204 E205	P204-M208 PolarHBondContact O-N 3.37Å; E205-M208 PolarHBondContact O-N 3Å
209	K	63.6	Low	69.9	Low	166 Å²	166	62.6 Å²	62.6	72%	0.722	30%	0.304	S	S	*	.	H	α-helix	trans	-72.4	-31.8	175.1	-73.5	174.3	-178.1	164.6	0	113.4	E205 W206 Y207	E205-K209 WeakPolarHBondContact O-CG 3.43Å; E205-K209 PolarHBondContact O-N 3.22Å; E205-K209 IonicContact OE2-NZ 3.98Å; W206-K209 PolarHBondContact O-N 3.18Å; Y207-K209 VanDerWaalsContact C-N 3.25Å; Y207-K209 PolarHBondContact O-N 3.46Å
210	V	67.8	Low	72.2	Confident	107 Å²	107	56.6 Å²	56.6	65%	0.648	28%	0.278	S	S	*	.	H	α-helix	trans	-89.7	-26.5	-177.7	177.5	0	0	0	0	112.1	W206 Y207 V212	W206-V210 VanDerWaalsContact O-CG2 3.29Å; W206-V210 WeakPolarHBondContact O-CG2 3.4Å; W206-V210 PolarHBondContact O-N 3.29Å; Y207-V210 PolarHBondContact O-N 2.8Å; Y207-V210 VanDerWaalsContact O-N 3.15Å; V210-V212 PolarHBondContact O-N 3.11Å
211	K	76.3	Confident	74.2	Confident	31 Å²	31	54.4 Å²	54.4	14%	0.135	27%	0.274	C	S	.	.	S	Bend	trans	-57.3	125.4	-178.5	-171.3	179.6	-172.5	104.7	0	110.9	Y207 P213 I215 E218	Y207-K211 HydrophobicContact CE1-CB 4.39Å; Y207-K211 HydrophobicContact CE1-CD 4.06Å; Y207-K211 HydrophobicContact CE1-CG 4.49Å; Y207-K211 WeakPolarHBondContact O-CB 3.17Å; Y207-K211 PolarHBondContact O-N 3.16Å; Y207-K211 PolarHBondContact OH-NZ 2.91Å; K211-P213 VanDerWaalsContact O-CD 3.27Å; K211-P213 WeakPolarHBondContact O-CD 3.21Å; K211-I215 WeakPolarHBondContact CE-O 3.13Å; K211-E218 IonicContact NZ-OE2 3.73Å
212	V	86.8	Confident	75.9	Confident	69 Å²	69	58.7 Å²	58.7	42%	0.418	29%	0.291	S	S	.	.	P	Polyproline II helix	trans	-72.5	118.5	174.5	-178.9	0	0	0	0	108.4	V210 G214 I215	V210-V212 PolarHBondContact O-N 3.11Å; V212-G214 PolarHBondContact O-N 2.9Å; V212-I215 HydrophobicContact CB-CD1 3.9Å; V212-I215 HydrophobicContact CB-CG1 4.34Å; V212-I215 HydrophobicContact CG1-CD1 4.15Å; V212-I215 HydrophobicContact CG1-CG1 4.42Å; V212-I215 PolarHBondContact O-N 2.65Å
213	P	89.4	Confident	76.9	Confident	5 Å²	5	61.5 Å²	61.5	3%	0.032	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-58.8	141.7	-179.4	-27.1	37.5	0	0	0	111.5	K211 D442 I443 G566 T567 R568	K211-P213 VanDerWaalsContact O-CD 3.27Å; K211-P213 WeakPolarHBondContact O-CD 3.21Å; P213-D442 HydrophobicContact CB-CB 3.9Å; P213-I443 HydrophobicContact CB-CG2 4.46Å; P213-I443 HydrophobicContact CG-CG2 4.13Å; P213-G566 CarbonylContact O-C 3.59Å; P213-G566 VanDerWaalsContact O-CA 3.31Å; P213-G566 WeakPolarHBondContact O-CA 3.35Å; P213-T567 PolarHBondContact O-N 3.14Å; P213-T567 PolarHBondContact O-OG1 2.95Å; P213-R568 HydrophobicContact CG-CG 4.45Å
214	G	90.1	Very high	77.8	Confident	0 Å²	0	62.9 Å²	62.9	0%	0	33%	0.327	C	S	.	.	T	Hydrogen-bonded Turn	trans	98.9	-26.1	-178.3	0	0	0	0	0	114.7	P96 V212 S216 W438 D442 I562 T567	P96-G214 WeakPolarHBondContact CG-O 3.15Å; V212-G214 PolarHBondContact O-N 2.9Å; G214-S216 PolarHBondContact O-N 3.08Å; G214-W438 PolarHBondContact O-NE1 3.26Å; G214-D442 WeakPolarHBondContact CA-OD2 3.39Å; G214-D442 PolarHBondContact N-OD2 2.94Å; G214-I562 WeakPolarHBondContact O-CG2 3.16Å; G214-T567 PolarHBondContact N-OG1 2.73Å
215	I	90.9	Very high	79	Confident	54 Å²	54	61.8 Å²	61.8	28%	0.277	32%	0.32	S	S	.	.			trans	-80	121.3	-178.4	-56.6	-175.2	0	0	0	109.9	K211 V212	K211-I215 WeakPolarHBondContact CE-O 3.13Å; V212-I215 HydrophobicContact CB-CD1 3.9Å; V212-I215 HydrophobicContact CB-CG1 4.34Å; V212-I215 HydrophobicContact CG1-CD1 4.15Å; V212-I215 HydrophobicContact CG1-CG1 4.42Å; V212-I215 PolarHBondContact O-N 2.65Å
216	S	90	Very high	80	Confident	5 Å²	5	60.3 Å²	60.3	4%	0.035	32%	0.315	C	S	.	.			trans	-157	157.7	177.4	179.2	0	0	0	0	109	K90 N95 P96 G214 P240	K90-S216 WeakPolarHBondContact CG-OG 3.46Å; N95-S216 WeakPolarHBondContact CA-O 3.46Å; N95-S216 VanDerWaalsContact CB-O 3.27Å; N95-S216 WeakPolarHBondContact CB-O 3.39Å; P96-S216 WeakPolarHBondContact CD-O 3.42Å; G214-S216 PolarHBondContact O-N 3.08Å; S216-P240 WeakPolarHBondContact OG-CD 3.48Å
217	P	91.5	Very high	81	Confident	19 Å²	19	56 Å²	56	12%	0.123	31%	0.305	C	S	.	.	S	Bend	cis	-69.4	170.1	-19.1	37.5	-40.6	0	0	0	110.9	G93 V237	G93-P217 WeakPolarHBondContact O-CB 3.5Å; G93-P217 WeakPolarHBondContact O-CD 3.37Å; G93-P217 WeakPolarHBondContact O-CG 3.42Å; P217-V237 HydrophobicContact CB-CB 3.94Å; P217-V237 HydrophobicContact CB-CG2 4.45Å; P217-V237 HydrophobicContact CG-CB 3.72Å; P217-V237 HydrophobicContact CG-CG1 3.96Å; P217-V237 HydrophobicContact CG-CG2 4.19Å
218	E	87	Confident	82.1	Confident	46 Å²	46	55.2 Å²	55.2	22%	0.215	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-76.5	129	167.6	-164.8	65.6	-172.6	0	0	110	Y207 K211 V237 S238	Y207-E218 WeakPolarHBondContact OH-CG 3.27Å; Y207-E218 PolarHBondContact OH-OE1 3.23Å; Y207-E218 PolarHBondContact OH-OE2 3.27Å; K211-E218 IonicContact NZ-OE2 3.73Å; E218-V237 CarbonylContact O-C 3.38Å; E218-V237 VanDerWaalsContact O-CA 3.26Å; E218-V237 WeakPolarHBondContact O-CA 3.36Å; E218-S238 PolarHBondContact N-O 3.03Å; E218-S238 PolarHBondContact O-N 2.97Å
219	V	88.2	Confident	83.2	Confident	89 Å²	89	53.6 Å²	53.6	54%	0.539	30%	0.295	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.9	116.4	173.9	-178.2	0	0	0	0	108.2	V237	V219-V237 HydrophobicContact CG2-CG1 4.32Å
220	L	86.2	Confident	84.3	Confident	5 Å²	5	48.2 Å²	48.2	3%	0.026	28%	0.277	C	S	.	.	P	Polyproline II helix	trans	-70.3	138.7	-177	-62.1	179.9	0	0	0	111	L156 L165 V225 Y228 L236 V245	L156-L220 HydrophobicContact CD1-CD2 4.28Å; L156-L220 HydrophobicContact CD2-CD1 4.14Å; L156-L220 HydrophobicContact CD2-CD2 4.3Å; L165-L220 HydrophobicContact CD2-CD1 4.2Å; L220-V225 HydrophobicContact CD1-CG2 4.45Å; L220-V225 HydrophobicContact CD2-CG2 3.94Å; L220-Y228 HydrophobicContact CB-CE1 4.45Å; L220-Y228 WeakPolarHBondContact O-CE1 3.35Å; L220-L236 HydrophobicContact CB-CB 4.39Å; L220-L236 HydrophobicContact CD1-CB 3.97Å; L220-L236 PolarHBondContact N-O 3.04Å; L220-L236 VanDerWaalsContact N-O 3.09Å; L220-V245 HydrophobicContact CD1-CB 4.5Å; L220-V245 HydrophobicContact CD1-CG1 3.62Å; L220-V245 HydrophobicContact CD1-CG2 4.01Å
221	S	83.3	Confident	85.2	Confident	45 Å²	45	51.9 Å²	51.9	32%	0.315	29%	0.287	S	S	.	.			trans	-130.6	158.8	176	65.7	0	0	0	0	110.7	S223 V224 V225	S221-S223 PolarHBondContact O-N 3.4Å; S221-S223 VanDerWaalsContact O-N 3.14Å; S221-S223 PolarHBondContact OG-OG 2.75Å; S221-V224 PolarHBondContact O-N 3.18Å; S221-V225 PolarHBondContact O-N 3.08Å; S221-V225 VanDerWaalsContact O-N 3.08Å
222	Q	81.5	Confident	85.7	Confident	118 Å²	118	58.5 Å²	58.5	55%	0.551	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.4	-25.9	176.3	-81.7	172.9	-11.9	0	0	113.3	V224 Y228	Q222-V224 VanDerWaalsContact C-N 3.28Å; Q222-V224 PolarHBondContact O-N 2.71Å; Q222-Y228 HydrophobicContact CG-CD1 4.41Å; Q222-Y228 WeakPolarHBondContact CG-O 3.43Å
223	S	76.9	Confident	85.7	Confident	105 Å²	105	57.1 Å²	57.1	73%	0.734	31%	0.305	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.4	-20.5	178.3	62.5	0	0	0	0	113.6	S221	S221-S223 PolarHBondContact O-N 3.4Å; S221-S223 VanDerWaalsContact O-N 3.14Å; S221-S223 PolarHBondContact OG-OG 2.75Å
224	V	75.9	Confident	85.6	Confident	45 Å²	45	58.4 Å²	58.4	27%	0.273	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	-103.1	-37.5	-177.5	-178.8	0	0	0	0	110.5	Q163 S221 Q222	Q163-V224 WeakPolarHBondContact CB-O 3.45Å; Q163-V224 VanDerWaalsContact OE1-CG1 3.32Å; S221-V224 PolarHBondContact O-N 3.18Å; Q222-V224 VanDerWaalsContact C-N 3.28Å; Q222-V224 PolarHBondContact O-N 2.71Å
225	V	82.6	Confident	85.7	Confident	0 Å²	0	65.5 Å²	65.5	0%	0	35%	0.351	C	S	.	.	B	Isolated β-bridge	trans	-121	112.4	-176.3	-174.9	0	0	0	0	110.5	L156 Q163 L165 L220 S221 N227 Y228	L156-V225 HydrophobicContact CD2-CG2 3.77Å; Q163-V225 HydrophobicContact CB-CG2 4.08Å; Q163-V225 WeakPolarHBondContact O-CA 3.38Å; L165-V225 HydrophobicContact CB-CG1 4.49Å; L165-V225 HydrophobicContact CD1-CG1 3.59Å; L165-V225 HydrophobicContact CG-CG1 3.76Å; L220-V225 HydrophobicContact CD1-CG2 4.45Å; L220-V225 HydrophobicContact CD2-CG2 3.94Å; S221-V225 PolarHBondContact O-N 3.08Å; S221-V225 VanDerWaalsContact O-N 3.08Å; V225-N227 VanDerWaalsContact C-N 3.32Å; V225-N227 WeakPolarHBondContact CG1-OD1 3.35Å; V225-N227 PolarHBondContact O-N 3.11Å; V225-Y228 WeakPolarHBondContact O-CB 3.46Å; V225-Y228 PolarHBondContact O-N 3.38Å
226	N	80.7	Confident	85.8	Confident	89 Å²	89	63 Å²	63	48%	0.476	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.8	-33.3	-167.8	-72.6	-6	0	0	0	113.9	S162 Q163 Y164	S162-N226 WeakPolarHBondContact CB-ND2 3.46Å; S162-N226 PolarHBondContact OG-ND2 3.4Å; Q163-N226 PolarHBondContact O-N 3.01Å; Y164-N226 HydrophobicContact CD1-CB 4.22Å; Y164-N226 HydrophobicContact CE1-CB 3.8Å; Y164-N226 PolarHBondContact OH-ND2 2.9Å
227	N	84.8	Confident	85.9	Confident	75 Å²	75	62.9 Å²	62.9	40%	0.401	34%	0.337	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.5	14.3	-177.8	70.8	-31.2	0	0	0	113.6	Y164 L165 V225	Y164-N227 WeakPolarHBondContact CA-OD1 3.45Å; Y164-N227 HydrophobicContact CD1-CB 4.49Å; L165-N227 PolarHBondContact N-ND2 3.43Å; L165-N227 PolarHBondContact N-OD1 3.22Å; L165-N227 PolarHBondContact O-ND2 2.95Å; V225-N227 VanDerWaalsContact C-N 3.32Å; V225-N227 WeakPolarHBondContact CG1-OD1 3.35Å; V225-N227 PolarHBondContact O-N 3.11Å
228	Y	86.6	Confident	85.8	Confident	12 Å²	12	62 Å²	62	5%	0.047	33%	0.331	C	S	.	.			trans	-82.7	118.6	177.5	174.4	-124.6	0	0	0	111.2	L165 L220 Q222 V225 P230 L233 G234 L236	L165-Y228 HydrophobicContact CD1-CD2 3.84Å; L165-Y228 HydrophobicContact CD1-CG 4.11Å; L220-Y228 HydrophobicContact CB-CE1 4.45Å; L220-Y228 WeakPolarHBondContact O-CE1 3.35Å; Q222-Y228 HydrophobicContact CG-CD1 4.41Å; Q222-Y228 WeakPolarHBondContact CG-O 3.43Å; V225-Y228 WeakPolarHBondContact O-CB 3.46Å; V225-Y228 PolarHBondContact O-N 3.38Å; Y228-P230 HydrophobicContact CE1-CB 4.03Å; Y228-L233 HydrophobicContact CD2-CB 4.47Å; Y228-L233 HydrophobicContact CD2-CD1 4.21Å; Y228-L233 HydrophobicContact CE2-CB 4.25Å; Y228-G234 WeakPolarHBondContact CE2-O 3.2Å; Y228-G234 PolarHBondContact OH-O 3.3Å; Y228-L236 HydrophobicContact CD2-CD1 3.86Å; Y228-L236 HydrophobicContact CD2-CG 4.46Å; Y228-L236 HydrophobicContact CE2-CB 4.1Å; Y228-L236 HydrophobicContact CE2-CD1 3.66Å; Y228-L236 HydrophobicContact CE2-CG 3.76Å; Y228-L236 PolarHBondContact OH-N 3.23Å
229	D	86.7	Confident	86	Confident	41 Å²	41	60 Å²	60	22%	0.219	32%	0.322	C	S	.	.			trans	-112	103.6	173.6	-172.8	-12.7	0	0	0	109.2	E231 K232 L233	D229-E231 PolarHBondContact O-N 2.98Å; D229-E231 PolarHBondContact OD1-N 3.3Å; D229-K232 HydrophobicContact CB-CB 4.27Å; D229-K232 HydrophobicContact CB-CD 4.36Å; D229-K232 HydrophobicContact CB-CG 4.46Å; D229-K232 PolarHBondContact O-N 2.88Å; D229-K232 WeakPolarHBondContact OD2-CD 3.25Å; D229-K232 WeakPolarHBondContact OD2-CE 3.41Å; D229-K232 WeakPolarHBondContact OD2-CG 3.48Å; D229-K232 IonicContact OD2-NZ 3.75Å; D229-K232 PolarHBondContact OD2-NZ 3.01Å; D229-L233 WeakPolarHBondContact O-CB 3.4Å; D229-L233 PolarHBondContact O-N 3.27Å
230	P	87	Confident	85.7	Confident	53 Å²	53	55.9 Å²	55.9	34%	0.344	30%	0.297	S	S	.	.	H	α-helix	trans	-66.3	-23.3	-176	28.1	-33.3	0	0	0	112.6	Y228 G234	Y228-P230 HydrophobicContact CE1-CB 4.03Å; P230-G234 WeakPolarHBondContact O-CA 3.32Å; P230-G234 PolarHBondContact O-N 2.9Å; P230-G234 VanDerWaalsContact O-N 3.12Å
231	E	87	Confident	85.4	Confident	184 Å²	184	57 Å²	57	86%	0.86	30%	0.302	S	S	*	.	H	α-helix	trans	-71.2	-35.2	176.5	-63.6	-171	169.1	0	0	111.3	D229	D229-E231 PolarHBondContact O-N 2.98Å; D229-E231 PolarHBondContact OD1-N 3.3Å
232	K	86.6	Confident	85.4	Confident	169 Å²	169	55.3 Å²	55.3	74%	0.735	29%	0.29	S	S	*	.	H	α-helix	trans	-88.9	-40.8	-179.4	-67.2	179.3	-171.9	145	0	113.5	D229	D229-K232 HydrophobicContact CB-CB 4.27Å; D229-K232 HydrophobicContact CB-CD 4.36Å; D229-K232 HydrophobicContact CB-CG 4.46Å; D229-K232 PolarHBondContact O-N 2.88Å; D229-K232 WeakPolarHBondContact OD2-CD 3.25Å; D229-K232 WeakPolarHBondContact OD2-CE 3.41Å; D229-K232 WeakPolarHBondContact OD2-CG 3.48Å; D229-K232 IonicContact OD2-NZ 3.75Å; D229-K232 PolarHBondContact OD2-NZ 3.01Å
233	L	85.9	Confident	85.5	Confident	40 Å²	40	50.5 Å²	50.5	21%	0.209	27%	0.267	C	S	.	.	H	α-helix	trans	-98.7	-12	-170.5	-61	179.4	0	0	0	113.2	F154 L165 Y228 D229 L236	F154-L233 HydrophobicContact CE1-CD2 4.34Å; F154-L233 HydrophobicContact CE2-CD2 4.26Å; F154-L233 HydrophobicContact CZ-CD2 3.66Å; L165-L233 HydrophobicContact CD1-CD1 4.44Å; Y228-L233 HydrophobicContact CD2-CB 4.47Å; Y228-L233 HydrophobicContact CD2-CD1 4.21Å; Y228-L233 HydrophobicContact CE2-CB 4.25Å; D229-L233 WeakPolarHBondContact O-CB 3.4Å; D229-L233 PolarHBondContact O-N 3.27Å; L233-L236 HydrophobicContact CB-CD1 4.18Å; L233-L236 HydrophobicContact CD1-CD1 4.36Å
234	G	89.1	Confident	86	Confident	32 Å²	32	46.5 Å²	46.5	33%	0.33	24%	0.237	S	C	.	.			trans	69	-169.7	-173.1	0	0	0	0	0	112.2	Y228 P230 L236	Y228-G234 WeakPolarHBondContact CE2-O 3.2Å; Y228-G234 PolarHBondContact OH-O 3.3Å; P230-G234 WeakPolarHBondContact O-CA 3.32Å; P230-G234 PolarHBondContact O-N 2.9Å; P230-G234 VanDerWaalsContact O-N 3.12Å; G234-L236 PolarHBondContact O-N 3.38Å
235	K	92.3	Very high	86.7	Confident	150 Å²	150	44.4 Å²	44.4	65%	0.652	22%	0.224	S	C	*	.			trans	-74.5	115	-179.1	-67.7	179.1	-178.1	174.1	0	111	K248	K235-K248 HydrophobicContact CB-CB 4.07Å; K235-K248 HydrophobicContact CB-CD 4.45Å; K235-K248 HydrophobicContact CD-CD 4.48Å; K235-K248 WeakPolarHBondContact O-CB 3.48Å; K235-K248 PolarHBondContact O-N 3Å
236	L	92.3	Very high	87.2	Confident	0 Å²	0	44.7 Å²	44.7	0%	0	23%	0.225	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-103.4	146.4	176.2	-61.8	-177.7	0	0	0	111.9	F154 L165 L220 Y228 L233 G234 V245 Y246 R247	F154-L236 HydrophobicContact CD2-CD1 3.94Å; F154-L236 HydrophobicContact CD2-CD2 4.2Å; F154-L236 HydrophobicContact CE2-CD1 4.21Å; F154-L236 HydrophobicContact CE2-CD2 4.22Å; L165-L236 HydrophobicContact CD1-CD1 4.12Å; L165-L236 HydrophobicContact CD2-CD1 4.03Å; L220-L236 HydrophobicContact CB-CB 4.39Å; L220-L236 HydrophobicContact CD1-CB 3.97Å; L220-L236 PolarHBondContact N-O 3.04Å; L220-L236 VanDerWaalsContact N-O 3.09Å; Y228-L236 HydrophobicContact CD2-CD1 3.86Å; Y228-L236 HydrophobicContact CD2-CG 4.46Å; Y228-L236 HydrophobicContact CE2-CB 4.1Å; Y228-L236 HydrophobicContact CE2-CD1 3.66Å; Y228-L236 HydrophobicContact CE2-CG 3.76Å; Y228-L236 PolarHBondContact OH-N 3.23Å; L233-L236 HydrophobicContact CB-CD1 4.18Å; L233-L236 HydrophobicContact CD1-CD1 4.36Å; G234-L236 PolarHBondContact O-N 3.38Å; L236-V245 HydrophobicContact CB-CG1 3.72Å; L236-V245 HydrophobicContact CD1-CG1 4Å; L236-V245 HydrophobicContact CD2-CG1 4.31Å; L236-V245 HydrophobicContact CG-CG1 4.22Å; L236-Y246 WeakPolarHBondContact CA-O 3.31Å; L236-R247 HydrophobicContact CD2-CG 3.88Å
237	V	92.7	Very high	87.8	Confident	4 Å²	4	45.5 Å²	45.5	2%	0.024	22%	0.222	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-132.1	143.6	178.1	-64.2	0	0	0	0	110.9	P217 E218 V219 Y246 K248 V251	P217-V237 HydrophobicContact CB-CB 3.94Å; P217-V237 HydrophobicContact CB-CG2 4.45Å; P217-V237 HydrophobicContact CG-CB 3.72Å; P217-V237 HydrophobicContact CG-CG1 3.96Å; P217-V237 HydrophobicContact CG-CG2 4.19Å; E218-V237 CarbonylContact O-C 3.38Å; E218-V237 VanDerWaalsContact O-CA 3.26Å; E218-V237 WeakPolarHBondContact O-CA 3.36Å; V219-V237 HydrophobicContact CG2-CG1 4.32Å; V237-Y246 PolarHBondContact N-O 3.25Å; V237-Y246 PolarHBondContact O-N 3.44Å; V237-K248 HydrophobicContact CG1-CB 4.2Å; V237-K248 HydrophobicContact CG1-CG 4.15Å; V237-V251 HydrophobicContact CG2-CG2 4.02Å
238	S	89.6	Confident	88.2	Confident	0 Å²	0	45.6 Å²	45.6	0%	0	22%	0.219	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-124.1	125.6	177.3	-168.2	0	0	0	0	110.7	L156 E218 K244	L156-S238 VanDerWaalsContact CD1-OG 3.31Å; L156-S238 WeakPolarHBondContact CD1-OG 3.37Å; E218-S238 PolarHBondContact N-O 3.03Å; E218-S238 PolarHBondContact O-N 2.97Å; S238-K244 PolarHBondContact OG-O 3.03Å
239	P	89.7	Confident	88.6	Confident	3 Å²	3	48 Å²	48	2%	0.019	24%	0.237	C	C	.	.			trans	-58.9	147.3	164.5	27.7	-38.2	0	0	0	111	H241 K244 Y246	P239-H241 VanDerWaalsContact C-N 3.32Å; P239-H241 PolarHBondContact O-N 3.09Å; P239-K244 WeakPolarHBondContact CD-O 3.2Å; P239-Y246 HydrophobicContact CG-CE2 3.96Å
240	P	81.6	Confident	89	Confident	4 Å²	4	46.6 Å²	46.6	3%	0.026	23%	0.231	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-28.1	-175.1	-23.1	32.5	0	0	0	115.7	S216	S216-P240 WeakPolarHBondContact OG-CD 3.48Å
241	H	81.1	Confident	89.4	Confident	28 Å²	28	44.2 Å²	44.2	13%	0.13	22%	0.215	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.2	20.8	-172.3	-56.5	-73.9	0	0	0	112.3	P239 Q329 Q441 D442	P239-H241 VanDerWaalsContact C-N 3.32Å; P239-H241 PolarHBondContact O-N 3.09Å; H241-Q329 HydrophobicContact CB-CB 4.39Å; H241-Q329 CarbonylContact O-C 3.45Å; H241-Q441 VanDerWaalsContact CD2-CD 3.49Å; H241-Q441 PolarHBondContact CE1-O 2.82Å; H241-D442 IonicContact NE2-OD1 3.87Å; H241-D442 PolarHBondContact NE2-OD1 3.03Å
242	S	83.7	Confident	89.8	Confident	9 Å²	9	39.2 Å²	39.2	6%	0.063	19%	0.192	C	C	.	.			trans	-138.9	145.8	176.2	164.9	0	0	0	0	112	K244 N327 E330	S242-K244 VanDerWaalsContact C-N 3.26Å; S242-K244 WeakPolarHBondContact OG-CB 3.2Å; S242-K244 PolarHBondContact OG-N 3.45Å; S242-K244 VanDerWaalsContact OG-N 3.12Å; S242-N327 WeakPolarHBondContact CA-ND2 3.47Å; S242-E330 WeakPolarHBondContact CB-OE2 3.5Å; S242-E330 PolarHBondContact OG-OE2 2.91Å
243	K	81.9	Confident	90.3	Very high	17 Å²	17	37.2 Å²	37.2	7%	0.074	19%	0.185	C	C	.	.	S	Bend	trans	-74	-18.1	175.3	-60.5	178.4	-172.8	-161.6	0	112.4	C155 L156 Y202 C324 L326 N327	C155-K243 CarbonylContact C-O 3.55Å; C155-K243 VanDerWaalsContact CA-O 3.31Å; C155-K243 WeakPolarHBondContact CA-O 3.49Å; L156-K243 PolarHBondContact N-O 3.35Å; Y202-K243 HydrophobicContact CD1-CG 3.96Å; Y202-K243 HydrophobicContact CD2-CD 4.39Å; Y202-K243 HydrophobicContact CD2-CG 4.07Å; Y202-K243 HydrophobicContact CE1-CB 4.26Å; Y202-K243 HydrophobicContact CE1-CD 3.74Å; Y202-K243 HydrophobicContact CE1-CG 3.65Å; Y202-K243 HydrophobicContact CE2-CD 3.68Å; Y202-K243 HydrophobicContact CE2-CG 3.87Å; Y202-K243 HydrophobicContact CG-CG 4.16Å; Y202-K243 VanDerWaalsContact OH-CD 3.27Å; Y202-K243 WeakPolarHBondContact OH-CD 3.41Å; Y202-K243 WeakPolarHBondContact OH-CE 3.43Å; Y202-K243 PolarHBondContact OH-NZ 3.45Å; K243-C324 HydrophobicContact CB-CB 3.99Å; K243-L326 WeakPolarHBondContact CE-O 3.29Å; K243-L326 PolarHBondContact NZ-O 2.92Å; K243-N327 HydrophobicContact CD-CB 4.06Å; K243-N327 HydrophobicContact CG-CB 4.3Å; K243-N327 PolarHBondContact N-ND2 2.82Å; K243-N327 VanDerWaalsContact N-ND2 3.15Å
244	K	88.2	Confident	90.8	Very high	22 Å²	22	36 Å²	36	10%	0.096	18%	0.18	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-66.5	138.4	-177.5	-70.9	173.5	174.8	154.4	0	110.4	A152 S238 P239 S242 Y246 H322 P323 E330	A152-K244 HydrophobicContact CB-CB 3.86Å; A152-K244 HydrophobicContact CB-CD 4.07Å; A152-K244 HydrophobicContact CB-CG 3.85Å; S238-K244 PolarHBondContact OG-O 3.03Å; P239-K244 WeakPolarHBondContact CD-O 3.2Å; S242-K244 VanDerWaalsContact C-N 3.26Å; S242-K244 WeakPolarHBondContact OG-CB 3.2Å; S242-K244 PolarHBondContact OG-N 3.45Å; S242-K244 VanDerWaalsContact OG-N 3.12Å; K244-Y246 HydrophobicContact CB-CE1 4.28Å; K244-Y246 HydrophobicContact CB-CE2 4.26Å; K244-Y246 HydrophobicContact CD-CE1 4.38Å; K244-Y246 VanDerWaalsContact CD-OH 3.3Å; K244-Y246 WeakPolarHBondContact CD-OH 3.47Å; K244-H322 WeakPolarHBondContact CE-NE2 3.42Å; K244-P323 HydrophobicContact CG-CG 4.46Å; K244-E330 WeakPolarHBondContact CE-OE1 3.44Å; K244-E330 IonicContact NZ-OE1 2.65Å; K244-E330 PolarHBondContact NZ-OE1 3.31Å
245	V	90.3	Very high	91.2	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	17%	0.17	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-117.4	128.3	172	178.4	0	0	0	0	108.7	P153 F154 L156 L165 L220 L236	P153-V245 WeakPolarHBondContact CD-O 3.42Å; F154-V245 HydrophobicContact CB-CB 4.09Å; F154-V245 PolarHBondContact O-N 2.99Å; L156-V245 HydrophobicContact CB-CG2 4.48Å; L156-V245 HydrophobicContact CD1-CG2 4.06Å; L156-V245 HydrophobicContact CD2-CG2 4.19Å; L156-V245 HydrophobicContact CG-CG2 3.53Å; L165-V245 HydrophobicContact CD2-CB 4.16Å; L165-V245 HydrophobicContact CD2-CG1 4Å; L165-V245 HydrophobicContact CD2-CG2 3.9Å; L220-V245 HydrophobicContact CD1-CB 4.5Å; L220-V245 HydrophobicContact CD1-CG1 3.62Å; L220-V245 HydrophobicContact CD1-CG2 4.01Å; L236-V245 HydrophobicContact CB-CG1 3.72Å; L236-V245 HydrophobicContact CD1-CG1 4Å; L236-V245 HydrophobicContact CD2-CG1 4.31Å; L236-V245 HydrophobicContact CG-CG1 4.22Å
246	Y	93.5	Very high	91.4	Very high	6 Å²	6	33.5 Å²	33.5	2%	0.024	16%	0.164	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-106.4	150.4	-179.7	-53.3	-71.9	0	0	0	110.6	Q91 P150 A152 L236 V237 P239 K244 V251	Q91-Y246 PolarHBondContact O-OH 3.21Å; P150-Y246 HydrophobicContact CB-CD1 3.92Å; P150-Y246 HydrophobicContact CB-CE1 4.31Å; P150-Y246 HydrophobicContact CB-CG 4.48Å; P150-Y246 HydrophobicContact CG-CD1 3.76Å; P150-Y246 HydrophobicContact CG-CE1 3.76Å; P150-Y246 HydrophobicContact CG-CG 4.24Å; P150-Y246 WeakPolarHBondContact O-CE1 3.21Å; A152-Y246 HydrophobicContact CB-CD1 3.97Å; A152-Y246 HydrophobicContact CB-CE1 3.68Å; L236-Y246 WeakPolarHBondContact CA-O 3.31Å; V237-Y246 PolarHBondContact N-O 3.25Å; V237-Y246 PolarHBondContact O-N 3.44Å; P239-Y246 HydrophobicContact CG-CE2 3.96Å; K244-Y246 HydrophobicContact CB-CE1 4.28Å; K244-Y246 HydrophobicContact CB-CE2 4.26Å; K244-Y246 HydrophobicContact CD-CE1 4.38Å; K244-Y246 VanDerWaalsContact CD-OH 3.3Å; K244-Y246 WeakPolarHBondContact CD-OH 3.47Å; Y246-V251 HydrophobicContact CD2-CG2 4.38Å; Y246-V251 HydrophobicContact CG-CG2 4.11Å
247	R	93.6	Very high	91.6	Very high	107 Å²	107	37.8 Å²	37.8	40%	0.404	19%	0.186	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-71.1	133.6	162	-69	179	-174.4	-111.6	4.7	108.3	P153 L236 S249 A250 V251	P153-R247 HydrophobicContact CG-CG 4.22Å; L236-R247 HydrophobicContact CD2-CG 3.88Å; R247-S249 PolarHBondContact O-N 3.22Å; R247-A250 HydrophobicContact CB-CB 4.28Å; R247-A250 PolarHBondContact O-N 2.92Å; R247-A250 VanDerWaalsContact O-N 3.09Å; R247-V251 PolarHBondContact O-N 3.48Å
248	K	93.6	Very high	91.8	Very high	77 Å²	77	37.6 Å²	37.6	34%	0.335	19%	0.185	S	C	.	.	H	α-helix	trans	-57.5	-38.3	-179.3	-165.9	-173	-178.3	-127.1	0	112.3	K235 V237 A250 V251 E252	K235-K248 HydrophobicContact CB-CB 4.07Å; K235-K248 HydrophobicContact CB-CD 4.45Å; K235-K248 HydrophobicContact CD-CD 4.48Å; K235-K248 WeakPolarHBondContact O-CB 3.48Å; K235-K248 PolarHBondContact O-N 3Å; V237-K248 HydrophobicContact CG1-CB 4.2Å; V237-K248 HydrophobicContact CG1-CG 4.15Å; K248-A250 PolarHBondContact O-N 2.84Å; K248-V251 PolarHBondContact O-N 3.24Å; K248-E252 WeakPolarHBondContact CE-OE1 3.34Å; K248-E252 IonicContact NZ-OE1 2.66Å; K248-E252 PolarHBondContact NZ-OE1 2.93Å; K248-E252 WeakPolarHBondContact O-CG 3.25Å; K248-E252 PolarHBondContact O-N 2.94Å
249	S	93.9	Very high	92.2	Very high	62 Å²	62	39.6 Å²	39.6	43%	0.434	20%	0.196	S	C	.	.	H	α-helix	trans	-61	-42.5	176.9	56.4	0	0	0	0	112.5	R247 V251 E252 E253	R247-S249 PolarHBondContact O-N 3.22Å; S249-V251 VanDerWaalsContact C-N 3.34Å; S249-V251 PolarHBondContact O-N 2.89Å; S249-E252 PolarHBondContact O-N 3.39Å; S249-E253 WeakPolarHBondContact O-CG 3.18Å; S249-E253 PolarHBondContact O-N 3.32Å
250	A	94.9	Very high	92.5	Very high	11 Å²	11	43.3 Å²	43.3	9%	0.091	22%	0.218	C	C	.	.	H	α-helix	trans	-64.5	-38.3	178.5	0	0	0	0	0	111.9	P150 R247 K248 E253 V254	P150-A250 HydrophobicContact CB-CB 4.38Å; R247-A250 HydrophobicContact CB-CB 4.28Å; R247-A250 PolarHBondContact O-N 2.92Å; R247-A250 VanDerWaalsContact O-N 3.09Å; K248-A250 PolarHBondContact O-N 2.84Å; A250-E253 PolarHBondContact O-N 3.37Å; A250-V254 WeakPolarHBondContact O-CB 3.06Å; A250-V254 VanDerWaalsContact O-CG2 3.32Å; A250-V254 WeakPolarHBondContact O-CG2 3.48Å; A250-V254 PolarHBondContact O-N 3.36Å
251	V	95.8	Very high	93.2	Very high	3 Å²	3	44.5 Å²	44.5	2%	0.018	23%	0.226	C	C	.	.	H	α-helix	trans	-65.7	-40.3	174.1	-179.6	0	0	0	0	111.1	M94 P150 V237 Y246 R247 K248 S249 F255	M94-V251 HydrophobicContact CG-CG1 3.94Å; P150-V251 HydrophobicContact CB-CG2 4.4Å; P150-V251 HydrophobicContact CG-CG2 4.41Å; V237-V251 HydrophobicContact CG2-CG2 4.02Å; Y246-V251 HydrophobicContact CD2-CG2 4.38Å; Y246-V251 HydrophobicContact CG-CG2 4.11Å; R247-V251 PolarHBondContact O-N 3.48Å; K248-V251 PolarHBondContact O-N 3.24Å; S249-V251 VanDerWaalsContact C-N 3.34Å; S249-V251 PolarHBondContact O-N 2.89Å; V251-F255 VanDerWaalsContact O-CB 3.31Å; V251-F255 WeakPolarHBondContact O-CB 3.33Å; V251-F255 PolarHBondContact O-N 3.21Å
252	E	95.7	Very high	93.9	Very high	79 Å²	79	43.2 Å²	43.2	37%	0.369	22%	0.219	S	C	.	.	H	α-helix	trans	-66.2	-40.8	177.2	-72.4	171.3	178	0	0	112	K248 S249 F255 L256	K248-E252 WeakPolarHBondContact CE-OE1 3.34Å; K248-E252 IonicContact NZ-OE1 2.66Å; K248-E252 PolarHBondContact NZ-OE1 2.93Å; K248-E252 WeakPolarHBondContact O-CG 3.25Å; K248-E252 PolarHBondContact O-N 2.94Å; S249-E252 PolarHBondContact O-N 3.39Å; E252-F255 WeakPolarHBondContact O-CB 3.46Å; E252-F255 PolarHBondContact O-N 2.92Å; E252-L256 WeakPolarHBondContact O-CG 3.43Å; E252-L256 PolarHBondContact O-N 2.98Å; E252-L256 VanDerWaalsContact O-N 3.09Å
253	E	96.2	Very high	94.5	Very high	127 Å²	127	45.1 Å²	45.1	59%	0.593	23%	0.231	S	C	*	.	H	α-helix	trans	-62.1	-48.4	173.4	-74.3	168	-158.8	0	0	111.9	S249 A250 F255 L256 L257	S249-E253 WeakPolarHBondContact O-CG 3.18Å; S249-E253 PolarHBondContact O-N 3.32Å; A250-E253 PolarHBondContact O-N 3.37Å; E253-F255 VanDerWaalsContact C-N 3.32Å; E253-F255 PolarHBondContact O-N 3.05Å; E253-L256 PolarHBondContact O-N 3.35Å; E253-L257 PolarHBondContact O-N 3.18Å
254	V	96.6	Very high	95.2	Very high	16 Å²	16	48.6 Å²	48.6	10%	0.097	25%	0.249	C	C	.	.	H	α-helix	trans	-62.2	-39.7	177.1	162.6	0	0	0	0	111.6	M94 I148 P150 A250 L256 L257 L258	M94-V254 HydrophobicContact CE-CG1 3.91Å; I148-V254 HydrophobicContact CG2-CB 4.49Å; I148-V254 HydrophobicContact CG2-CG1 3.82Å; I148-V254 HydrophobicContact CG2-CG2 4.46Å; P150-V254 HydrophobicContact CB-CG2 4Å; A250-V254 WeakPolarHBondContact O-CB 3.06Å; A250-V254 VanDerWaalsContact O-CG2 3.32Å; A250-V254 WeakPolarHBondContact O-CG2 3.48Å; A250-V254 PolarHBondContact O-N 3.36Å; V254-L256 PolarHBondContact O-N 3.15Å; V254-L257 PolarHBondContact O-N 3.29Å; V254-L258 HydrophobicContact CG1-CD1 3.83Å; V254-L258 HydrophobicContact CG1-CG 4.41Å; V254-L258 WeakPolarHBondContact O-CB 3.1Å; V254-L258 WeakPolarHBondContact O-CG 3.41Å; V254-L258 PolarHBondContact O-N 3.18Å
255	F	97.4	Very high	95.5	Very high	26 Å²	26	47.8 Å²	47.8	11%	0.114	25%	0.247	C	C	.	.	H	α-helix	trans	-58.4	-46.1	173.2	162.1	-102.7	0	0	0	112.1	M94 Q98 I101 L102 V251 E252 E253 L258 L259	M94-F255 HydrophobicContact CE-CB 3.91Å; M94-F255 HydrophobicContact SD-CB 4.38Å; M94-F255 HydrophobicContact SD-CD2 4.37Å; Q98-F255 HydrophobicContact CB-CD2 3.55Å; Q98-F255 HydrophobicContact CB-CE2 3.74Å; Q98-F255 HydrophobicContact CB-CG 4.18Å; Q98-F255 HydrophobicContact CB-CZ 4.5Å; Q98-F255 HydrophobicContact CG-CD1 4.22Å; Q98-F255 HydrophobicContact CG-CD2 3.72Å; Q98-F255 HydrophobicContact CG-CE1 4.4Å; Q98-F255 HydrophobicContact CG-CE2 3.92Å; Q98-F255 HydrophobicContact CG-CG 3.88Å; Q98-F255 HydrophobicContact CG-CZ 4.25Å; Q98-F255 WeakPolarHBondContact O-CE2 3.19Å; I101-F255 HydrophobicContact CB-CE2 4.28Å; I101-F255 HydrophobicContact CB-CZ 4.33Å; I101-F255 HydrophobicContact CD1-CZ 4.24Å; I101-F255 HydrophobicContact CG2-CE2 4.3Å; I101-F255 HydrophobicContact CG2-CZ 4.11Å; L102-F255 HydrophobicContact CD1-CD2 4.01Å; L102-F255 HydrophobicContact CD1-CE2 4.47Å; L102-F255 HydrophobicContact CD2-CD2 3.98Å; L102-F255 HydrophobicContact CD2-CE2 3.91Å; L102-F255 HydrophobicContact CG-CD2 3.91Å; L102-F255 HydrophobicContact CG-CE2 3.88Å; V251-F255 VanDerWaalsContact O-CB 3.31Å; V251-F255 WeakPolarHBondContact O-CB 3.33Å; V251-F255 PolarHBondContact O-N 3.21Å; E252-F255 WeakPolarHBondContact O-CB 3.46Å; E252-F255 PolarHBondContact O-N 2.92Å; E253-F255 VanDerWaalsContact C-N 3.32Å; E253-F255 PolarHBondContact O-N 3.05Å; F255-L258 PolarHBondContact O-N 3.25Å; F255-L259 HydrophobicContact CZ-CD2 4.47Å; F255-L259 WeakPolarHBondContact O-CB 3.43Å; F255-L259 PolarHBondContact O-N 3.34Å
256	L	97.2	Very high	95.7	Very high	102 Å²	102	48 Å²	48	53%	0.534	25%	0.248	S	C	.	.	H	α-helix	trans	-65.1	-40.7	178	-69.6	173.7	0	0	0	111.8	E252 E253 V254 L259 V260	E252-L256 WeakPolarHBondContact O-CG 3.43Å; E252-L256 PolarHBondContact O-N 2.98Å; E252-L256 VanDerWaalsContact O-N 3.09Å; E253-L256 PolarHBondContact O-N 3.35Å; V254-L256 PolarHBondContact O-N 3.15Å; L256-L259 WeakPolarHBondContact O-CB 3.49Å; L256-L259 PolarHBondContact O-N 3.25Å; L256-V260 WeakPolarHBondContact O-CG2 3.31Å; L256-V260 PolarHBondContact O-N 2.94Å; L256-V260 VanDerWaalsContact O-N 3.14Å
257	L	97	Very high	95.8	Very high	90 Å²	90	51 Å²	51	47%	0.471	26%	0.261	S	S	.	.	H	α-helix	trans	-63.7	-46.2	177	-170.3	69	0	0	0	111.4	I148 E253 V254 L259 V260 V261	I148-L257 HydrophobicContact CB-CD2 4.31Å; I148-L257 HydrophobicContact CD1-CD2 3.79Å; I148-L257 HydrophobicContact CD1-CG 3.86Å; I148-L257 HydrophobicContact CG1-CD2 3.65Å; I148-L257 HydrophobicContact CG1-CG 4.29Å; I148-L257 HydrophobicContact CG2-CB 4.34Å; I148-L257 HydrophobicContact CG2-CD2 3.7Å; I148-L257 HydrophobicContact CG2-CG 4.25Å; E253-L257 PolarHBondContact O-N 3.18Å; V254-L257 PolarHBondContact O-N 3.29Å; L257-L259 VanDerWaalsContact C-N 3.32Å; L257-L259 PolarHBondContact O-N 2.7Å; L257-V260 PolarHBondContact O-N 2.93Å; L257-V261 WeakPolarHBondContact O-CG2 3.5Å; L257-V261 PolarHBondContact O-N 2.81Å
258	L	97.1	Very high	95.8	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-62.6	-38.2	175.4	-76.5	169.4	0	0	0	111.9	F89 L92 M94 L102 M145 I148 V254 F255 V260 V261 I262	F89-L258 HydrophobicContact CD1-CD1 4.32Å; F89-L258 HydrophobicContact CE1-CD1 4.08Å; L92-L258 HydrophobicContact CD1-CD1 4.06Å; M94-L258 HydrophobicContact CE-CD1 3.46Å; M94-L258 VanDerWaalsContact CE-CD1 3.46Å; L102-L258 HydrophobicContact CD1-CB 4.17Å; L102-L258 HydrophobicContact CD1-CD1 4.43Å; L102-L258 HydrophobicContact CD2-CB 4.11Å; M145-L258 HydrophobicContact CB-CD2 4Å; M145-L258 HydrophobicContact CG-CD2 3.97Å; I148-L258 HydrophobicContact CB-CD2 3.96Å; I148-L258 HydrophobicContact CB-CG 4.31Å; I148-L258 HydrophobicContact CD1-CD2 4.19Å; I148-L258 HydrophobicContact CG2-CD1 4.26Å; I148-L258 HydrophobicContact CG2-CD2 3.89Å; I148-L258 HydrophobicContact CG2-CG 3.67Å; V254-L258 HydrophobicContact CG1-CD1 3.83Å; V254-L258 HydrophobicContact CG1-CG 4.41Å; V254-L258 WeakPolarHBondContact O-CB 3.1Å; V254-L258 WeakPolarHBondContact O-CG 3.41Å; V254-L258 PolarHBondContact O-N 3.18Å; F255-L258 PolarHBondContact O-N 3.25Å; L258-V260 VanDerWaalsContact C-N 3.32Å; L258-V260 PolarHBondContact O-N 3.23Å; L258-V261 PolarHBondContact O-N 3.48Å; L258-I262 VanDerWaalsContact O-CB 3.23Å; L258-I262 WeakPolarHBondContact O-CB 3.26Å; L258-I262 WeakPolarHBondContact O-CG1 3.1Å; L258-I262 PolarHBondContact O-N 2.69Å
259	L	97.2	Very high	95.8	Very high	43 Å²	43	45.9 Å²	45.9	23%	0.225	24%	0.242	C	C	.	.	H	α-helix	trans	-59.6	-44	176.4	-179.4	62.2	0	0	0	111.4	I101 L102 I105 F255 L256 L257 T263	I101-L259 HydrophobicContact CG2-CD1 3.96Å; L102-L259 HydrophobicContact CD2-CB 3.81Å; L102-L259 HydrophobicContact CD2-CD1 4.18Å; I105-L259 HydrophobicContact CG2-CD1 4.3Å; F255-L259 HydrophobicContact CZ-CD2 4.47Å; F255-L259 WeakPolarHBondContact O-CB 3.43Å; F255-L259 PolarHBondContact O-N 3.34Å; L256-L259 WeakPolarHBondContact O-CB 3.49Å; L256-L259 PolarHBondContact O-N 3.25Å; L257-L259 VanDerWaalsContact C-N 3.32Å; L257-L259 PolarHBondContact O-N 2.7Å; L259-T263 VanDerWaalsContact O-CB 3.26Å; L259-T263 WeakPolarHBondContact O-CB 3.34Å; L259-T263 PolarHBondContact O-N 3.25Å; L259-T263 PolarHBondContact O-OG1 3.33Å
260	V	96.8	Very high	95.5	Very high	80 Å²	80	43.2 Å²	43.2	49%	0.485	22%	0.224	S	C	.	.	H	α-helix	trans	-66.3	-49.9	177.1	173.5	0	0	0	0	110.9	L256 L257 L258 I262 T263 I264	L256-V260 WeakPolarHBondContact O-CG2 3.31Å; L256-V260 PolarHBondContact O-N 2.94Å; L256-V260 VanDerWaalsContact O-N 3.14Å; L257-V260 PolarHBondContact O-N 2.93Å; L258-V260 VanDerWaalsContact C-N 3.32Å; L258-V260 PolarHBondContact O-N 3.23Å; V260-I262 PolarHBondContact O-N 3.15Å; V260-T263 PolarHBondContact O-N 3.12Å; V260-I264 HydrophobicContact CG1-CD1 3.63Å; V260-I264 HydrophobicContact CG1-CG1 4.4Å; V260-I264 WeakPolarHBondContact O-CB 3.42Å; V260-I264 VanDerWaalsContact O-CG1 3.32Å; V260-I264 WeakPolarHBondContact O-CG1 3.37Å; V260-I264 PolarHBondContact O-N 2.96Å
261	V	96.4	Very high	95.2	Very high	30 Å²	30	42.8 Å²	42.8	18%	0.182	22%	0.22	C	C	.	.	H	α-helix	trans	-62.7	-43.2	-178.2	170.6	0	0	0	0	111.8	A144 M145 I148 L257 L258 G265	A144-V261 HydrophobicContact CB-CG1 3.97Å; M145-V261 HydrophobicContact CG-CG1 4.18Å; I148-V261 HydrophobicContact CD1-CB 4.31Å; I148-V261 HydrophobicContact CD1-CG1 4.5Å; I148-V261 HydrophobicContact CD1-CG2 3.75Å; L257-V261 WeakPolarHBondContact O-CG2 3.5Å; L257-V261 PolarHBondContact O-N 2.81Å; L258-V261 PolarHBondContact O-N 3.48Å; V261-G265 WeakPolarHBondContact O-CA 3.32Å; V261-G265 PolarHBondContact O-N 3.44Å
262	I	95.8	Very high	94.9	Very high	0 Å²	0	42.6 Å²	42.6	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-64	-48.5	175.7	-70.2	170.1	0	0	0	110	F89 L102 I105 R106 M145 L258 V260 I264 G265 E266	F89-I262 HydrophobicContact CZ-CD1 3.81Å; L102-I262 HydrophobicContact CB-CD1 3.99Å; L102-I262 HydrophobicContact CD2-CD1 4.08Å; L102-I262 HydrophobicContact CG-CD1 4.43Å; I105-I262 HydrophobicContact CG2-CG2 4.11Å; R106-I262 HydrophobicContact CG-CG2 3.74Å; M145-I262 HydrophobicContact CE-CB 4.4Å; M145-I262 HydrophobicContact CE-CG1 3.57Å; M145-I262 HydrophobicContact CG-CG1 4.26Å; M145-I262 HydrophobicContact SD-CD1 4.19Å; M145-I262 HydrophobicContact SD-CG1 3.64Å; L258-I262 VanDerWaalsContact O-CB 3.23Å; L258-I262 WeakPolarHBondContact O-CB 3.26Å; L258-I262 WeakPolarHBondContact O-CG1 3.1Å; L258-I262 PolarHBondContact O-N 2.69Å; V260-I262 PolarHBondContact O-N 3.15Å; I262-I264 PolarHBondContact O-N 2.85Å; I262-G265 PolarHBondContact O-N 2.93Å; I262-E266 HydrophobicContact CG2-CG 4.03Å; I262-E266 WeakPolarHBondContact O-CB 3.1Å; I262-E266 WeakPolarHBondContact O-CG 3.42Å; I262-E266 PolarHBondContact O-N 2.67Å
263	T	95.8	Very high	94.4	Very high	49 Å²	49	39.9 Å²	39.9	30%	0.301	21%	0.207	S	C	.	.	H	α-helix	trans	-60.3	-45.6	-178.1	-59	0	0	0	0	111.8	V109 L259 V260 F267	V109-T263 HydrophobicContact CG2-CG2 3.96Å; L259-T263 VanDerWaalsContact O-CB 3.26Å; L259-T263 WeakPolarHBondContact O-CB 3.34Å; L259-T263 PolarHBondContact O-N 3.25Å; L259-T263 PolarHBondContact O-OG1 3.33Å; V260-T263 PolarHBondContact O-N 3.12Å; T263-F267 WeakPolarHBondContact O-CB 3.19Å; T263-F267 PolarHBondContact O-N 3.41Å; T263-F267 VanDerWaalsContact O-N 3.11Å
264	I	96.1	Very high	93.7	Very high	90 Å²	90	36.4 Å²	36.4	46%	0.462	20%	0.195	S	C	.	.	H	α-helix	trans	-66.8	-47.1	177.8	-67.9	175.3	0	0	0	110.5	V260 I262 F267 F268	V260-I264 HydrophobicContact CG1-CD1 3.63Å; V260-I264 HydrophobicContact CG1-CG1 4.4Å; V260-I264 WeakPolarHBondContact O-CB 3.42Å; V260-I264 VanDerWaalsContact O-CG1 3.32Å; V260-I264 WeakPolarHBondContact O-CG1 3.37Å; V260-I264 PolarHBondContact O-N 2.96Å; I262-I264 PolarHBondContact O-N 2.85Å; I264-F267 PolarHBondContact O-N 3.38Å; I264-F268 HydrophobicContact CG2-CD2 3.75Å; I264-F268 HydrophobicContact CG2-CE2 3.71Å; I264-F268 VanDerWaalsContact O-CD2 3.22Å; I264-F268 WeakPolarHBondContact O-CD2 3.41Å; I264-F268 PolarHBondContact O-N 3.23Å
265	G	95.4	Very high	93.1	Very high	5 Å²	5	36.4 Å²	36.4	5%	0.052	19%	0.194	C	C	.	.	H	α-helix	trans	-56.8	-51.6	178.5	0	0	0	0	0	111.9	V261 I262 F267 F268 S269	V261-G265 WeakPolarHBondContact O-CA 3.32Å; V261-G265 PolarHBondContact O-N 3.44Å; I262-G265 PolarHBondContact O-N 2.93Å; G265-F267 VanDerWaalsContact C-N 3.35Å; G265-F267 PolarHBondContact O-N 2.94Å; G265-F268 PolarHBondContact O-N 3.43Å; G265-S269 WeakPolarHBondContact O-CB 3.38Å; G265-S269 PolarHBondContact O-N 3.39Å; G265-S269 PolarHBondContact O-OG 3.39Å
266	E	94.3	Very high	92.5	Very high	5 Å²	5	35.1 Å²	35.1	2%	0.023	19%	0.188	C	C	.	.	H	α-helix	trans	-60.1	-42.9	177.8	-69.9	-50.4	114.1	0	0	112.5	R106 V109 W138 I262 F268 S269 A270	R106-E266 HydrophobicContact CB-CG 3.92Å; R106-E266 HydrophobicContact CG-CG 3.91Å; R106-E266 IonicContact CZ-OE1 3.55Å; R106-E266 IonicContact CZ-OE2 3.67Å; R106-E266 VanDerWaalsContact CZ-OE2 3.29Å; R106-E266 IonicContact NE-OE2 2.7Å; R106-E266 IonicContact NH1-OE1 2.99Å; R106-E266 PolarHBondContact NH1-OE1 2.92Å; R106-E266 IonicContact NH1-OE2 2.83Å; R106-E266 IonicContact NH2-OE1 4Å; R106-E266 PolarHBondContact NH2-OE1 2.58Å; R106-E266 IonicContact NH2-OE2 2.89Å; R106-E266 PolarHBondContact NH2-OE2 3.22Å; V109-E266 HydrophobicContact CB-CB 4.06Å; V109-E266 HydrophobicContact CG1-CB 3.72Å; W138-E266 WeakPolarHBondContact CH2-OE1 3.26Å; W138-E266 VanDerWaalsContact CH2-OE2 3.27Å; W138-E266 WeakPolarHBondContact CH2-OE2 3.46Å; W138-E266 WeakPolarHBondContact CZ3-OE1 3.28Å; I262-E266 HydrophobicContact CG2-CG 4.03Å; I262-E266 WeakPolarHBondContact O-CB 3.1Å; I262-E266 WeakPolarHBondContact O-CG 3.42Å; I262-E266 PolarHBondContact O-N 2.67Å; E266-F268 VanDerWaalsContact C-N 3.35Å; E266-F268 PolarHBondContact O-N 3.28Å; E266-S269 PolarHBondContact O-N 2.86Å; E266-A270 WeakPolarHBondContact O-CB 3.17Å; E266-A270 PolarHBondContact O-N 3.37Å
267	F	94.6	Very high	91.6	Very high	68 Å²	68	32.2 Å²	32.2	30%	0.298	17%	0.173	S	C	.	.	H	α-helix	trans	-59	-46.5	-179.2	178.2	-93.7	0	0	0	111.8	V109 F116 W117 T263 I264 G265	V109-F267 HydrophobicContact CG1-CB 3.74Å; V109-F267 VanDerWaalsContact CG1-N 3.34Å; F116-F267 AromaticContact CD1-CZ 3.9Å; F116-F267 HydrophobicContact CD1-CZ 3.9Å; F116-F267 HydrophobicContact CE1-CE1 4.35Å; F116-F267 AromaticContact CE1-CZ 3.96Å; F116-F267 HydrophobicContact CE1-CZ 3.96Å; F116-F267 HydrophobicContact CG-CZ 4.49Å; W117-F267 HydrophobicContact CZ2-CD1 4.28Å; W117-F267 AromaticContact CZ2-CE1 3.88Å; W117-F267 HydrophobicContact CZ2-CE1 3.88Å; W117-F267 PolarHBondContact NE1-O 2.81Å; T263-F267 WeakPolarHBondContact O-CB 3.19Å; T263-F267 PolarHBondContact O-N 3.41Å; T263-F267 VanDerWaalsContact O-N 3.11Å; I264-F267 PolarHBondContact O-N 3.38Å; G265-F267 VanDerWaalsContact C-N 3.35Å; G265-F267 PolarHBondContact O-N 2.94Å
268	F	94.7	Very high	90.6	Very high	77 Å²	77	31 Å²	31	34%	0.338	17%	0.172	S	C	.	.	H	α-helix	trans	-76.6	-23.4	-180	-72.2	-65.7	0	0	0	113.5	W117 F133 C137 I264 G265 E266	W117-F268 AromaticContact CH2-CD1 3.88Å; W117-F268 HydrophobicContact CH2-CD1 3.88Å; W117-F268 HydrophobicContact CH2-CE1 4.3Å; W117-F268 AromaticContact CZ2-CD1 3.62Å; W117-F268 HydrophobicContact CZ2-CD1 3.62Å; W117-F268 HydrophobicContact CZ2-CE1 4.19Å; F133-F268 HydrophobicContact CE1-CB 4.21Å; F133-F268 AromaticContact CE1-CD1 3.73Å; F133-F268 HydrophobicContact CE1-CD1 3.73Å; F133-F268 HydrophobicContact CE1-CG 4.33Å; F133-F268 AromaticContact CZ-CD1 3.88Å; F133-F268 HydrophobicContact CZ-CD1 3.88Å; F133-F268 HydrophobicContact CZ-CE1 4.42Å; F133-F268 HydrophobicContact CZ-CG 4.41Å; C137-F268 HydrophobicContact CB-CB 3.85Å; I264-F268 HydrophobicContact CG2-CD2 3.75Å; I264-F268 HydrophobicContact CG2-CE2 3.71Å; I264-F268 VanDerWaalsContact O-CD2 3.22Å; I264-F268 WeakPolarHBondContact O-CD2 3.41Å; I264-F268 PolarHBondContact O-N 3.23Å; G265-F268 PolarHBondContact O-N 3.43Å; E266-F268 VanDerWaalsContact C-N 3.35Å; E266-F268 PolarHBondContact O-N 3.28Å
269	S	93.2	Very high	89.9	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-97.1	-13.9	-173	-46.8	0	0	0	0	113.7	C137 W138 G265 E266 A272	C137-S269 VanDerWaalsContact C-OG 3.22Å; C137-S269 VanDerWaalsContact CB-OG 3.29Å; C137-S269 WeakPolarHBondContact CB-OG 3.47Å; W138-S269 VanDerWaalsContact CD1-CB 3.45Å; W138-S269 PolarHBondContact N-OG 3.04Å; W138-S269 VanDerWaalsContact N-OG 3.12Å; W138-S269 VanDerWaalsContact NE1-CB 3.28Å; W138-S269 PolarHBondContact NE1-O 3.44Å; G265-S269 WeakPolarHBondContact O-CB 3.38Å; G265-S269 PolarHBondContact O-N 3.39Å; G265-S269 PolarHBondContact O-OG 3.39Å; E266-S269 PolarHBondContact O-N 2.86Å; S269-A272 WeakPolarHBondContact O-CB 3.3Å; S269-A272 PolarHBondContact O-N 3.41Å
270	A	88.4	Confident	89	Confident	7 Å²	7	29.1 Å²	29.1	6%	0.058	16%	0.163	C	C	.	.	T	Hydrogen-bonded Turn	trans	-52.4	-41	-179.3	0	0	0	0	0	116.7	E110 S113 E266 A272	E110-A270 HydrophobicContact CG-CB 4.34Å; S113-A270 WeakPolarHBondContact OG-CB 3.44Å; E266-A270 WeakPolarHBondContact O-CB 3.17Å; E266-A270 PolarHBondContact O-N 3.37Å; A270-A272 PolarHBondContact O-N 2.83Å
271	P	87.7	Confident	87.8	Confident	1 Å²	1	28.6 Å²	28.6	1%	0.006	16%	0.157	C	C	.	.	H	α-helix	trans	-76.2	-4	-174.9	30.6	-35.2	0	0	0	114.4	W117 V130 A134 I273 T274 L275	W117-P271 HydrophobicContact CB-CB 3.46Å; W117-P271 VanDerWaalsContact CB-CB 3.46Å; W117-P271 HydrophobicContact CB-CG 3.75Å; W117-P271 HydrophobicContact CD2-CG 3.79Å; W117-P271 HydrophobicContact CE3-CG 4.26Å; W117-P271 HydrophobicContact CG-CB 3.83Å; W117-P271 HydrophobicContact CG-CG 3.53Å; V130-P271 HydrophobicContact CG1-CB 4.39Å; V130-P271 HydrophobicContact CG1-CG 4.08Å; A134-P271 HydrophobicContact CB-CG 3.9Å; P271-I273 PolarHBondContact O-N 2.82Å; P271-T274 WeakPolarHBondContact CA-OG1 3.41Å; P271-T274 PolarHBondContact O-N 3.31Å; P271-T274 PolarHBondContact O-OG1 3.44Å; P271-T274 VanDerWaalsContact O-OG1 3.11Å; P271-L275 HydrophobicContact CB-CD1 3.98Å; P271-L275 HydrophobicContact CB-CG 4.33Å; P271-L275 VanDerWaalsContact O-CB 3.32Å; P271-L275 WeakPolarHBondContact O-CB 3.25Å; P271-L275 VanDerWaalsContact O-CG 3.27Å; P271-L275 WeakPolarHBondContact O-CG 3.32Å; P271-L275 PolarHBondContact O-N 3.11Å
272	A	90.1	Very high	86.7	Confident	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-57.1	-47.9	-176.3	0	0	0	0	0	112.1	F74 L131 A134 L135 S269 A270 A276	F74-A272 HydrophobicContact CE2-CB 4.04Å; F74-A272 HydrophobicContact CZ-CB 4.35Å; L131-A272 HydrophobicContact CD1-CB 4.23Å; L131-A272 WeakPolarHBondContact CD1-O 3.4Å; A134-A272 HydrophobicContact CB-CB 3.9Å; L135-A272 HydrophobicContact CD2-CB 3.99Å; L135-A272 HydrophobicContact CG-CB 4.41Å; S269-A272 WeakPolarHBondContact O-CB 3.3Å; S269-A272 PolarHBondContact O-N 3.41Å; A270-A272 PolarHBondContact O-N 2.83Å; A272-A276 WeakPolarHBondContact O-CB 3.48Å; A272-A276 PolarHBondContact O-N 2.92Å
273	I	85.1	Confident	85.8	Confident	21 Å²	21	34.1 Å²	34.1	11%	0.108	19%	0.185	C	C	.	.	H	α-helix	trans	-74.6	-41.3	-177.6	-169.4	60.3	0	0	0	112.1	Y71 F74 Y75 P271 L275 A276 D277	Y71-I273 HydrophobicContact CD1-CD1 4.47Å; Y71-I273 HydrophobicContact CE1-CD1 3.92Å; F74-I273 HydrophobicContact CD1-CD1 4.24Å; F74-I273 HydrophobicContact CE1-CB 4.24Å; F74-I273 HydrophobicContact CE1-CD1 3.89Å; F74-I273 HydrophobicContact CE1-CG1 4.43Å; F74-I273 HydrophobicContact CZ-CB 4.21Å; Y75-I273 HydrophobicContact CE2-CD1 3.87Å; Y75-I273 WeakPolarHBondContact OH-CD1 3.07Å; Y75-I273 WeakPolarHBondContact OH-CG1 3.46Å; P271-I273 PolarHBondContact O-N 2.82Å; I273-L275 PolarHBondContact O-N 2.82Å; I273-A276 PolarHBondContact O-N 2.9Å; I273-D277 WeakPolarHBondContact O-CB 3.29Å; I273-D277 PolarHBondContact O-N 2.96Å
274	T	81.3	Confident	84.5	Confident	55 Å²	55	32.5 Å²	32.5	34%	0.337	17%	0.174	S	C	.	.	H	α-helix	trans	-64.1	-41.8	-178.2	56.1	0	0	0	0	111.4	P271 D277 S278	P271-T274 WeakPolarHBondContact CA-OG1 3.41Å; P271-T274 PolarHBondContact O-N 3.31Å; P271-T274 PolarHBondContact O-OG1 3.44Å; P271-T274 VanDerWaalsContact O-OG1 3.11Å; T274-D277 PolarHBondContact O-N 2.94Å; T274-S278 PolarHBondContact O-N 3.39Å; T274-S278 PolarHBondContact O-OG 3.3Å; T274-S278 VanDerWaalsContact O-OG 3.07Å
275	L	82.5	Confident	83.3	Confident	15 Å²	15	30.6 Å²	30.6	8%	0.079	18%	0.177	C	C	.	.	H	α-helix	trans	-69.6	-36.3	176.6	-68.4	172.6	0	0	0	112.6	A121 V130 L131 P271 I273 C279	A121-L275 HydrophobicContact CB-CD2 3.69Å; V130-L275 HydrophobicContact CB-CD1 3.75Å; V130-L275 HydrophobicContact CG1-CD1 3.59Å; L131-L275 HydrophobicContact CB-CB 4.27Å; L131-L275 HydrophobicContact CB-CD1 4.17Å; L131-L275 HydrophobicContact CD1-CB 4.44Å; P271-L275 HydrophobicContact CB-CD1 3.98Å; P271-L275 HydrophobicContact CB-CG 4.33Å; P271-L275 VanDerWaalsContact O-CB 3.32Å; P271-L275 WeakPolarHBondContact O-CB 3.25Å; P271-L275 VanDerWaalsContact O-CG 3.27Å; P271-L275 WeakPolarHBondContact O-CG 3.32Å; P271-L275 PolarHBondContact O-N 3.11Å; I273-L275 PolarHBondContact O-N 2.82Å; L275-C279 VanDerWaalsContact O-CB 3.28Å; L275-C279 WeakPolarHBondContact O-CB 3.31Å; L275-C279 PolarHBondContact O-N 3.43Å
276	A	86	Confident	81.8	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-66.5	-39.6	175.1	0	0	0	0	0	112.2	F70 A272 I273 C279 T280 F354	F70-A276 HydrophobicContact CD1-CB 4.02Å; F70-A276 HydrophobicContact CE1-CB 3.22Å; F70-A276 HydrophobicContact CZ-CB 3.61Å; A272-A276 WeakPolarHBondContact O-CB 3.48Å; A272-A276 PolarHBondContact O-N 2.92Å; I273-A276 PolarHBondContact O-N 2.9Å; A276-C279 PolarHBondContact O-N 3.44Å; A276-T280 WeakPolarHBondContact O-CB 3.25Å; A276-T280 PolarHBondContact O-N 3.36Å; A276-T280 PolarHBondContact O-OG1 2.91Å; A276-F354 HydrophobicContact CB-CE2 4.03Å
277	D	78.6	Confident	80.4	Confident	40 Å²	40	42.3 Å²	42.3	21%	0.214	23%	0.23	C	C	.	.	H	α-helix	trans	-64.4	-48.9	175.5	-71.6	6.7	0	0	0	110.9	Y71 I273 T274 C279 T280 L281 Y291	Y71-D277 VanDerWaalsContact CE1-OD1 3.26Å; Y71-D277 WeakPolarHBondContact CE1-OD1 3.3Å; Y71-D277 VanDerWaalsContact OH-CA 3.28Å; Y71-D277 WeakPolarHBondContact OH-CA 3.42Å; Y71-D277 PolarHBondContact OH-OD1 3.31Å; I273-D277 WeakPolarHBondContact O-CB 3.29Å; I273-D277 PolarHBondContact O-N 2.96Å; T274-D277 PolarHBondContact O-N 2.94Å; D277-C279 VanDerWaalsContact C-N 3.34Å; D277-C279 PolarHBondContact O-N 3.36Å; D277-T280 PolarHBondContact O-N 2.93Å; D277-L281 WeakPolarHBondContact O-CB 3.14Å; D277-L281 VanDerWaalsContact O-CG 3.32Å; D277-L281 WeakPolarHBondContact O-CG 3.25Å; D277-L281 PolarHBondContact O-N 3.22Å; D277-Y291 HydrophobicContact CB-CE2 4.46Å; D277-Y291 PolarHBondContact OD1-OH 3.42Å; D277-Y291 PolarHBondContact OD2-OH 2.94Å
278	S	75.7	Confident	78.6	Confident	65 Å²	65	40.5 Å²	40.5	46%	0.455	23%	0.225	S	C	.	.	H	α-helix	trans	-59.6	-42.7	175.1	-61.7	0	0	0	0	112.3	T274 L281 N282	T274-S278 PolarHBondContact O-N 3.39Å; T274-S278 PolarHBondContact O-OG 3.3Å; T274-S278 VanDerWaalsContact O-OG 3.07Å; S278-L281 PolarHBondContact O-N 2.98Å; S278-N282 VanDerWaalsContact O-CG 3.23Å; S278-N282 PolarHBondContact O-N 3.45Å; S278-N282 VanDerWaalsContact O-N 3.09Å; S278-N282 PolarHBondContact O-ND2 2.97Å
279	C	81.4	Confident	76.5	Confident	2 Å²	2	39.5 Å²	39.5	1%	0.014	22%	0.222	C	C	.	.	H	α-helix	trans	-63.9	-45.5	177.1	-171.9	0	0	0	0	111.6	L275 A276 D277 L281 N282 M283 F354 F356	L275-C279 VanDerWaalsContact O-CB 3.28Å; L275-C279 WeakPolarHBondContact O-CB 3.31Å; L275-C279 PolarHBondContact O-N 3.43Å; A276-C279 PolarHBondContact O-N 3.44Å; D277-C279 VanDerWaalsContact C-N 3.34Å; D277-C279 PolarHBondContact O-N 3.36Å; C279-L281 PolarHBondContact O-N 3.38Å; C279-N282 PolarHBondContact O-N 3.17Å; C279-M283 VanDerWaalsContact O-CG 3.24Å; C279-M283 WeakPolarHBondContact O-CG 3.48Å; C279-M283 PolarHBondContact O-N 2.93Å; C279-F354 HydrophobicContact CB-CD2 4.19Å; C279-F356 HydrophobicContact CB-CE1 3.98Å; C279-F356 HydrophobicContact CB-CE2 4.3Å; C279-F356 HydrophobicContact CB-CZ 3.83Å
280	T	79.3	Confident	75	Confident	2 Å²	2	42.3 Å²	42.3	1%	0.012	24%	0.235	C	C	.	.	H	α-helix	trans	-63.8	-41.4	179.3	-62.3	0	0	0	0	111.8	S67 Y71 A276 D277 N282 M283 L284 Y291 Q294	S67-T280 WeakPolarHBondContact OG-CG2 3.5Å; S67-T280 PolarHBondContact OG-OG1 3.22Å; Y71-T280 HydrophobicContact CE2-CG2 4.05Å; Y71-T280 WeakPolarHBondContact CE2-OG1 3.36Å; Y71-T280 PolarHBondContact OH-OG1 3.47Å; A276-T280 WeakPolarHBondContact O-CB 3.25Å; A276-T280 PolarHBondContact O-N 3.36Å; A276-T280 PolarHBondContact O-OG1 2.91Å; D277-T280 PolarHBondContact O-N 2.93Å; T280-N282 VanDerWaalsContact C-N 3.3Å; T280-N282 PolarHBondContact O-N 3.46Å; T280-M283 PolarHBondContact O-N 3.09Å; T280-L284 HydrophobicContact CG2-CD1 4.24Å; T280-L284 WeakPolarHBondContact O-CG 3.47Å; T280-L284 PolarHBondContact O-N 2.95Å; T280-Y291 HydrophobicContact CG2-CD2 4.07Å; T280-Y291 HydrophobicContact CG2-CE2 4.25Å; T280-Q294 HydrophobicContact CG2-CB 4.08Å; T280-Q294 HydrophobicContact CG2-CG 3.92Å
281	L	71.3	Confident	73.9	Confident	69 Å²	69	43 Å²	43	36%	0.361	24%	0.237	S	C	.	.	H	α-helix	trans	-61.1	-40.7	175.7	-74.2	168.2	0	0	0	111.4	D277 S278 C279 L284 G285 P288 Y291	D277-L281 WeakPolarHBondContact O-CB 3.14Å; D277-L281 VanDerWaalsContact O-CG 3.32Å; D277-L281 WeakPolarHBondContact O-CG 3.25Å; D277-L281 PolarHBondContact O-N 3.22Å; S278-L281 PolarHBondContact O-N 2.98Å; C279-L281 PolarHBondContact O-N 3.38Å; L281-L284 PolarHBondContact O-N 2.9Å; L281-G285 PolarHBondContact O-N 3.29Å; L281-P288 HydrophobicContact CD2-CB 4.4Å; L281-Y291 HydrophobicContact CD2-CD1 4.45Å; L281-Y291 HydrophobicContact CD2-CD2 3.71Å; L281-Y291 HydrophobicContact CD2-CE2 4.49Å; L281-Y291 HydrophobicContact CD2-CG 3.71Å; L281-Y291 HydrophobicContact CG-CD2 3.93Å; L281-Y291 HydrophobicContact CG-CE2 4.3Å; L281-Y291 HydrophobicContact CG-CG 4.39Å
282	N	74.5	Confident	72.8	Confident	110 Å²	110	43.8 Å²	43.8	59%	0.588	25%	0.246	S	C	*	.	H	α-helix	trans	-64.6	-40.4	174.8	-68.1	-18.3	0	0	0	112.1	S278 C279 T280 L284 G285	S278-N282 VanDerWaalsContact O-CG 3.23Å; S278-N282 PolarHBondContact O-N 3.45Å; S278-N282 VanDerWaalsContact O-N 3.09Å; S278-N282 PolarHBondContact O-ND2 2.97Å; C279-N282 PolarHBondContact O-N 3.17Å; T280-N282 VanDerWaalsContact C-N 3.3Å; T280-N282 PolarHBondContact O-N 3.46Å; N282-L284 VanDerWaalsContact C-N 3.27Å; N282-L284 PolarHBondContact O-N 2.9Å; N282-G285 PolarHBondContact O-N 3.48Å; N282-G285 VanDerWaalsContact O-N 3.16Å
283	M	75	Confident	71.8	Confident	35 Å²	35	51.7 Å²	51.7	17%	0.172	28%	0.275	C	S	.	.	H	α-helix	trans	-66.1	-27.8	177.4	-66.3	163.3	76.6	0	0	113.1	E63 C279 T280 G285 F354	E63-M283 VanDerWaalsContact C-CE 3.44Å; E63-M283 HydrophobicContact CB-CE 3.49Å; E63-M283 VanDerWaalsContact CB-CE 3.49Å; E63-M283 HydrophobicContact CG-CE 4.13Å; E63-M283 WeakPolarHBondContact O-CE 3.4Å; C279-M283 VanDerWaalsContact O-CG 3.24Å; C279-M283 WeakPolarHBondContact O-CG 3.48Å; C279-M283 PolarHBondContact O-N 2.93Å; T280-M283 PolarHBondContact O-N 3.09Å; M283-G285 VanDerWaalsContact C-N 3.31Å; M283-F354 HydrophobicContact SD-CD1 4.5Å
284	L	68.6	Low	71.3	Confident	15 Å²	15	50.9 Å²	50.9	8%	0.079	27%	0.271	C	S	.	.	H	α-helix	trans	-75.8	-20.1	175.7	-74.6	171.5	0	0	0	113	L64 T280 L281 N282 E286 H287 M290 Y291 Q294	L64-L284 HydrophobicContact CD2-CD2 4.02Å; L64-L284 HydrophobicContact CG-CD2 4.36Å; T280-L284 HydrophobicContact CG2-CD1 4.24Å; T280-L284 WeakPolarHBondContact O-CG 3.47Å; T280-L284 PolarHBondContact O-N 2.95Å; L281-L284 PolarHBondContact O-N 2.9Å; N282-L284 VanDerWaalsContact C-N 3.27Å; N282-L284 PolarHBondContact O-N 2.9Å; L284-E286 PolarHBondContact O-N 2.89Å; L284-E286 VanDerWaalsContact O-N 3.12Å; L284-H287 PolarHBondContact O-N 3.07Å; L284-M290 HydrophobicContact CD2-CB 3.88Å; L284-Y291 VanDerWaalsContact CD1-CA 3.48Å; L284-Y291 HydrophobicContact CD1-CD2 4.39Å; L284-Q294 HydrophobicContact CD1-CG 4.2Å; L284-Q294 HydrophobicContact CD2-CG 4.45Å
285	G	71.9	Confident	71.1	Confident	51 Å²	51	51.1 Å²	51.1	53%	0.526	27%	0.266	S	S	.	.	T	Hydrogen-bonded Turn	trans	54.3	-113.8	176	0	0	0	0	0	112.5	L281 N282 M283 H287	L281-G285 PolarHBondContact O-N 3.29Å; N282-G285 PolarHBondContact O-N 3.48Å; N282-G285 VanDerWaalsContact O-N 3.16Å; M283-G285 VanDerWaalsContact C-N 3.31Å; G285-H287 PolarHBondContact O-N 3.44Å
286	E	63.5	Low	70.9	Confident	150 Å²	150	53.8 Å²	53.8	70%	0.701	28%	0.28	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.5	-7.7	-177.8	-64.6	179.9	176.6	0	0	114.1	L284 P288	L284-E286 PolarHBondContact O-N 2.89Å; L284-E286 VanDerWaalsContact O-N 3.12Å; E286-P288 VanDerWaalsContact O-CD 3.23Å; E286-P288 WeakPolarHBondContact O-CD 3.46Å
287	H	65.2	Low	70.9	Confident	105 Å²	105	58.1 Å²	58.1	49%	0.486	30%	0.297	S	S	.	.			trans	-116.7	52.8	-178.5	-63	-61.4	0	0	0	114.3	L284 G285 E289 M290	L284-H287 PolarHBondContact O-N 3.07Å; G285-H287 PolarHBondContact O-N 3.44Å; H287-E289 WeakPolarHBondContact CA-OE1 3.2Å; H287-E289 VanDerWaalsContact CA-OE2 3.25Å; H287-E289 WeakPolarHBondContact CA-OE2 3.22Å; H287-E289 WeakPolarHBondContact CB-OE1 3.23Å; H287-E289 IonicContact CG-OE1 2.72Å; H287-E289 IonicContact ND1-OE1 3.95Å; H287-E289 PolarHBondContact ND1-OE1 2.92Å; H287-E289 PolarHBondContact O-N 3.34Å; H287-E289 VanDerWaalsContact O-N 3.08Å; H287-M290 HydrophobicContact CB-CG 4.08Å; H287-M290 WeakPolarHBondContact O-CB 3.39Å; H287-M290 PolarHBondContact O-N 2.83Å
288	P	55.8	Low	71.4	Confident	31 Å²	31	56.2 Å²	56.2	20%	0.201	29%	0.287	C	S	.	.	G	3₁₀ helix	trans	-61.4	-16.7	178.4	30.2	-38.1	0	0	0	112.9	L281 E286 M290 Y291 L611	L281-P288 HydrophobicContact CD2-CB 4.4Å; E286-P288 VanDerWaalsContact O-CD 3.23Å; E286-P288 WeakPolarHBondContact O-CD 3.46Å; P288-M290 PolarHBondContact O-N 3.38Å; P288-Y291 WeakPolarHBondContact O-CB 3.47Å; P288-Y291 PolarHBondContact O-N 3.4Å; P288-Y291 VanDerWaalsContact O-N 3.07Å; P288-L611 HydrophobicContact CB-CD1 3.75Å; P288-L611 HydrophobicContact CB-CD2 4.27Å; P288-L611 HydrophobicContact CG-CD1 3.37Å; P288-L611 HydrophobicContact CG-CD2 4.07Å; P288-L611 HydrophobicContact CG-CG 4.33Å
289	E	51.5	Low	71.9	Confident	55 Å²	55	54.2 Å²	54.2	26%	0.257	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-62.8	-22.9	172.4	69.1	-77.3	178.4	0	0	112.5	H287 Y291 L611 G615 P617	H287-E289 WeakPolarHBondContact CA-OE1 3.2Å; H287-E289 VanDerWaalsContact CA-OE2 3.25Å; H287-E289 WeakPolarHBondContact CA-OE2 3.22Å; H287-E289 WeakPolarHBondContact CB-OE1 3.23Å; H287-E289 IonicContact CG-OE1 2.72Å; H287-E289 IonicContact ND1-OE1 3.95Å; H287-E289 PolarHBondContact ND1-OE1 2.92Å; H287-E289 PolarHBondContact O-N 3.34Å; H287-E289 VanDerWaalsContact O-N 3.08Å; E289-Y291 PolarHBondContact O-N 2.95Å; E289-L611 HydrophobicContact CB-CD2 3.45Å; E289-L611 VanDerWaalsContact CB-CD2 3.45Å; E289-G615 CarbonylContact C-O 3.53Å; E289-G615 WeakPolarHBondContact CA-O 3.1Å; E289-G615 WeakPolarHBondContact CB-O 3.18Å; E289-G615 CarbonylContact O-C 3.58Å; E289-G615 VanDerWaalsContact O-C 3.23Å; E289-G615 WeakPolarHBondContact O-CA 3.41Å; E289-P617 HydrophobicContact CB-CB 4.19Å; E289-P617 HydrophobicContact CB-CG 4.12Å; E289-P617 HydrophobicContact CG-CG 4.38Å
290	M	62.7	Low	72.2	Confident	59 Å²	59	58.7 Å²	58.7	29%	0.291	30%	0.296	S	S	.	.	G	3₁₀ helix	trans	-79.7	-3.8	178.3	-61.5	-69.6	-81.1	0	0	112.3	L284 H287 P288 G292 R293 Q294	L284-M290 HydrophobicContact CD2-CB 3.88Å; H287-M290 HydrophobicContact CB-CG 4.08Å; H287-M290 WeakPolarHBondContact O-CB 3.39Å; H287-M290 PolarHBondContact O-N 2.83Å; P288-M290 PolarHBondContact O-N 3.38Å; M290-G292 VanDerWaalsContact C-N 3.33Å; M290-G292 PolarHBondContact O-N 2.91Å; M290-R293 WeakPolarHBondContact O-CB 3.28Å; M290-R293 PolarHBondContact O-N 3.29Å; M290-Q294 PolarHBondContact O-N 3.43Å
291	Y	65.3	Low	72.8	Confident	21 Å²	21	58.6 Å²	58.6	8%	0.082	30%	0.295	C	S	.	.	H	α-helix	trans	-56.1	-43.7	-179.8	178.6	-108.4	0	0	0	112.9	Y71 D277 T280 L281 L284 P288 E289 R293 Q294 R295	Y71-Y291 WeakPolarHBondContact OH-CE2 3.32Å; Y71-Y291 PolarHBondContact OH-OH 3.49Å; D277-Y291 HydrophobicContact CB-CE2 4.46Å; D277-Y291 PolarHBondContact OD1-OH 3.42Å; D277-Y291 PolarHBondContact OD2-OH 2.94Å; T280-Y291 HydrophobicContact CG2-CD2 4.07Å; T280-Y291 HydrophobicContact CG2-CE2 4.25Å; L281-Y291 HydrophobicContact CD2-CD1 4.45Å; L281-Y291 HydrophobicContact CD2-CD2 3.71Å; L281-Y291 HydrophobicContact CD2-CE2 4.49Å; L281-Y291 HydrophobicContact CD2-CG 3.71Å; L281-Y291 HydrophobicContact CG-CD2 3.93Å; L281-Y291 HydrophobicContact CG-CE2 4.3Å; L281-Y291 HydrophobicContact CG-CG 4.39Å; L284-Y291 VanDerWaalsContact CD1-CA 3.48Å; L284-Y291 HydrophobicContact CD1-CD2 4.39Å; P288-Y291 WeakPolarHBondContact O-CB 3.47Å; P288-Y291 PolarHBondContact O-N 3.4Å; P288-Y291 VanDerWaalsContact O-N 3.07Å; E289-Y291 PolarHBondContact O-N 2.95Å; Y291-R293 PolarHBondContact O-N 3.47Å; Y291-Q294 WeakPolarHBondContact O-CA 3.17Å; Y291-Q294 WeakPolarHBondContact O-CB 3.43Å; Y291-Q294 PolarHBondContact O-N 3.02Å; Y291-R295 HydrophobicContact CE1-CB 4.44Å; Y291-R295 PolarHBondContact O-N 2.94Å
292	G	63	Low	73.8	Confident	19 Å²	19	57.1 Å²	57.1	20%	0.196	29%	0.285	C	S	.	.	H	α-helix	trans	-57.9	-37.2	176.5	0	0	0	0	0	113.4	M290 Q294 R295 L296 H614	M290-G292 VanDerWaalsContact C-N 3.33Å; M290-G292 PolarHBondContact O-N 2.91Å; G292-Q294 VanDerWaalsContact C-N 3.27Å; G292-Q294 PolarHBondContact O-N 2.85Å; G292-R295 PolarHBondContact O-N 3.25Å; G292-L296 WeakPolarHBondContact O-CB 3.38Å; G292-L296 PolarHBondContact O-N 3.43Å; G292-H614 WeakPolarHBondContact CA-O 3.24Å; G292-H614 PolarHBondContact N-O 3.22Å
293	R	70.1	Confident	74.6	Confident	165 Å²	165	52.1 Å²	52.1	62%	0.623	26%	0.259	S	S	*	.	H	α-helix	trans	-69	-26.8	177.8	-62	-172.7	-179.7	-176.4	2.2	112.3	M290 Y291 Y297	M290-R293 WeakPolarHBondContact O-CB 3.28Å; M290-R293 PolarHBondContact O-N 3.29Å; Y291-R293 PolarHBondContact O-N 3.47Å; R293-Y297 WeakPolarHBondContact O-CD2 3.36Å
294	Q	75	Confident	75.5	Confident	4 Å²	4	54.2 Å²	54.2	2%	0.019	27%	0.271	C	S	.	.	H	α-helix	trans	-72.9	-52.2	171.4	-51.5	-58.4	-11.7	0	0	110	Y71 T280 L284 M290 Y291 G292 L296 Y297	Y71-Q294 HydrophobicContact CD2-CB 4.25Å; Y71-Q294 HydrophobicContact CE2-CB 4.21Å; T280-Q294 HydrophobicContact CG2-CB 4.08Å; T280-Q294 HydrophobicContact CG2-CG 3.92Å; L284-Q294 HydrophobicContact CD1-CG 4.2Å; L284-Q294 HydrophobicContact CD2-CG 4.45Å; M290-Q294 PolarHBondContact O-N 3.43Å; Y291-Q294 WeakPolarHBondContact O-CA 3.17Å; Y291-Q294 WeakPolarHBondContact O-CB 3.43Å; Y291-Q294 PolarHBondContact O-N 3.02Å; G292-Q294 VanDerWaalsContact C-N 3.27Å; G292-Q294 PolarHBondContact O-N 2.85Å; Q294-L296 PolarHBondContact O-N 3.46Å; Q294-Y297 PolarHBondContact O-N 3.18Å; Q294-Y297 VanDerWaalsContact O-N 3.15Å
295	R	75.5	Confident	76.8	Confident	60 Å²	60	54 Å²	54	23%	0.226	27%	0.271	C	S	.	.	H	α-helix	trans	-63.7	-27.2	-176	-172.8	61.5	-176.4	70.7	11.3	113.6	Y75 Y291 G292 Y297 G298	Y75-R295 VanDerWaalsContact CE1-NH2 3.32Å; Y75-R295 VanDerWaalsContact CE2-NE 3.35Å; Y75-R295 PolarHBondContact OH-NE 2.95Å; Y75-R295 PolarHBondContact OH-NH2 3.48Å; Y291-R295 HydrophobicContact CE1-CB 4.44Å; Y291-R295 PolarHBondContact O-N 2.94Å; G292-R295 PolarHBondContact O-N 3.25Å; R295-Y297 PolarHBondContact O-N 3.12Å; R295-G298 WeakPolarHBondContact O-CA 3.46Å; R295-G298 PolarHBondContact O-N 3.16Å
296	L	78.8	Confident	77.8	Confident	71 Å²	71	51.6 Å²	51.6	37%	0.372	25%	0.246	S	C	.	.	H	α-helix	trans	-54.9	-35.2	174.3	-178.6	65.7	0	0	0	113	G292 Q294 G298 S299 L300 I462	G292-L296 WeakPolarHBondContact O-CB 3.38Å; G292-L296 PolarHBondContact O-N 3.43Å; Q294-L296 PolarHBondContact O-N 3.46Å; L296-G298 PolarHBondContact O-N 3.31Å; L296-S299 PolarHBondContact O-N 3.38Å; L296-S299 VanDerWaalsContact O-N 3.12Å; L296-L300 PolarHBondContact O-N 2.81Å; L296-I462 HydrophobicContact CD1-CB 4.48Å; L296-I462 HydrophobicContact CD1-CD1 3.74Å; L296-I462 HydrophobicContact CD1-CG1 3.58Å; L296-I462 HydrophobicContact CD1-CG2 4.17Å
297	Y	86.9	Confident	79.3	Confident	92 Å²	92	48 Å²	48	36%	0.361	23%	0.228	S	C	.	.	H	α-helix	trans	-63.2	-25.7	176.1	-81.4	-100	0	0	0	112.2	K68 F72 R293 Q294 R295 L300 G301	K68-Y297 HydrophobicContact CB-CD1 4.12Å; K68-Y297 HydrophobicContact CB-CD2 4.02Å; K68-Y297 HydrophobicContact CB-CE1 4.39Å; K68-Y297 HydrophobicContact CB-CE2 4.3Å; K68-Y297 HydrophobicContact CB-CG 3.92Å; K68-Y297 HydrophobicContact CD-CD2 4.04Å; K68-Y297 HydrophobicContact CD-CE1 4.43Å; K68-Y297 HydrophobicContact CD-CE2 3.56Å; K68-Y297 HydrophobicContact CG-CD2 3.78Å; K68-Y297 HydrophobicContact CG-CE2 3.85Å; K68-Y297 HydrophobicContact CG-CG 4.21Å; K68-Y297 WeakPolarHBondContact O-CB 3.46Å; F72-Y297 WeakPolarHBondContact CA-O 3.48Å; R293-Y297 WeakPolarHBondContact O-CD2 3.36Å; Q294-Y297 PolarHBondContact O-N 3.18Å; Q294-Y297 VanDerWaalsContact O-N 3.15Å; R295-Y297 PolarHBondContact O-N 3.12Å; Y297-L300 PolarHBondContact O-N 3.02Å; Y297-G301 PolarHBondContact O-N 3.25Å
298	G	87.8	Confident	80.8	Confident	0 Å²	0	47.4 Å²	47.4	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-66.5	-43.3	172.4	0	0	0	0	0	113	Y71 Y75 R295 L296 L300 G301 W302	Y71-G298 WeakPolarHBondContact O-CA 3.45Å; Y75-G298 WeakPolarHBondContact CB-O 3.26Å; R295-G298 WeakPolarHBondContact O-CA 3.46Å; R295-G298 PolarHBondContact O-N 3.16Å; L296-G298 PolarHBondContact O-N 3.31Å; G298-L300 VanDerWaalsContact C-N 3.29Å; G298-L300 PolarHBondContact O-N 2.88Å; G298-G301 PolarHBondContact O-N 2.62Å; G298-W302 PolarHBondContact O-N 3.31Å
299	S	86.3	Confident	82.6	Confident	23 Å²	23	46.4 Å²	46.4	16%	0.161	22%	0.22	C	C	.	.	H	α-helix	trans	-62.9	-38.1	175.3	-60.8	0	0	0	0	111.8	L296 G303 H458	L296-S299 PolarHBondContact O-N 3.38Å; L296-S299 VanDerWaalsContact O-N 3.12Å; S299-G303 PolarHBondContact O-N 3.05Å; S299-G303 VanDerWaalsContact O-N 3.13Å; S299-H458 PolarHBondContact O-CD2 2.99Å
300	L	87.8	Confident	84.6	Confident	95 Å²	95	43.8 Å²	43.8	50%	0.497	21%	0.208	S	C	.	.	H	α-helix	trans	-62.6	-47.4	173.6	-179.1	66.5	0	0	0	111.6	F72 L296 Y297 G298 L304	F72-L300 HydrophobicContact CD2-CD2 4.36Å; F72-L300 HydrophobicContact CD2-CG 4.39Å; F72-L300 HydrophobicContact CE2-CD2 4.25Å; F72-L300 HydrophobicContact CE2-CG 4.13Å; L296-L300 PolarHBondContact O-N 2.81Å; Y297-L300 PolarHBondContact O-N 3.02Å; G298-L300 VanDerWaalsContact C-N 3.29Å; G298-L300 PolarHBondContact O-N 2.88Å; L300-L304 WeakPolarHBondContact O-CB 3.42Å; L300-L304 PolarHBondContact O-N 2.85Å; L300-L304 VanDerWaalsContact O-N 3.09Å
301	G	92.9	Very high	86	Confident	0 Å²	0	43.8 Å²	43.8	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-59.5	-45.9	177.8	0	0	0	0	0	112.5	A76 Y297 G298 S305	A76-G301 WeakPolarHBondContact CA-O 3.39Å; A76-G301 WeakPolarHBondContact CB-O 3.36Å; Y297-G301 PolarHBondContact O-N 3.25Å; G298-G301 PolarHBondContact O-N 2.62Å; G301-S305 WeakPolarHBondContact O-CB 2.98Å; G301-S305 PolarHBondContact O-N 3.08Å
302	W	92.9	Very high	87.3	Confident	39 Å²	39	44.4 Å²	44.4	15%	0.148	22%	0.218	C	C	.	.	H	α-helix	trans	-59.4	-55.3	178	-172.8	-59.6	0	0	0	112.1	Y75 F78 F82 P83 G298 L304 S305 M306 F433 H458	Y75-W302 AromaticContact CD1-CE3 3.97Å; Y75-W302 HydrophobicContact CD1-CE3 3.97Å; Y75-W302 HydrophobicContact CD1-CZ3 4.3Å; Y75-W302 WeakPolarHBondContact O-CA 3.18Å; F78-W302 HydrophobicContact CB-CE3 3.7Å; F78-W302 HydrophobicContact CB-CH2 4.1Å; F78-W302 HydrophobicContact CB-CZ3 3.38Å; F78-W302 HydrophobicContact CD1-CZ3 4.47Å; F78-W302 HydrophobicContact CG-CZ3 4.2Å; F82-W302 HydrophobicContact CB-CH2 4.48Å; P83-W302 HydrophobicContact CG-CZ2 3.74Å; G298-W302 PolarHBondContact O-N 3.31Å; W302-L304 PolarHBondContact O-N 3.34Å; W302-S305 PolarHBondContact O-N 3.37Å; W302-M306 WeakPolarHBondContact O-CB 3.43Å; W302-M306 PolarHBondContact O-N 3.45Å; W302-F433 HydrophobicContact CH2-CE2 4.27Å; W302-F433 HydrophobicContact CZ2-CE2 4.19Å; W302-H458 AromaticContact CD1-CE1 3.06Å; W302-H458 AromaticContact CD1-ND1 3.97Å; W302-H458 AromaticContact CD1-NE2 3.38Å; W302-H458 AromaticContact CG-CE1 3.59Å; W302-H458 AromaticContact CG-NE2 3.39Å; W302-H458 AromaticContact NE1-CE1 3.51Å; W302-H458 AromaticContact NE1-NE2 3.97Å
303	G	90.7	Very high	88.6	Confident	5 Å²	5	43.5 Å²	43.5	5%	0.052	21%	0.209	C	C	.	.	H	α-helix	trans	-61.1	-43.5	-175.9	0	0	0	0	0	112.4	S299 F307 V455	S299-G303 PolarHBondContact O-N 3.05Å; S299-G303 VanDerWaalsContact O-N 3.13Å; G303-F307 WeakPolarHBondContact O-CB 3.41Å; G303-F307 PolarHBondContact O-N 3.35Å; G303-F307 VanDerWaalsContact O-N 3.12Å; G303-V455 WeakPolarHBondContact O-CG2 3.34Å
304	L	93.2	Very high	89.4	Confident	79 Å²	79	37.2 Å²	37.2	41%	0.414	19%	0.188	S	C	.	.	H	α-helix	trans	-66	-46.9	178.9	-179.2	62.8	0	0	0	112.2	F72 L300 W302 F307 I308	F72-L304 HydrophobicContact CE2-CD2 4.44Å; F72-L304 HydrophobicContact CZ-CD2 4.08Å; L300-L304 WeakPolarHBondContact O-CB 3.42Å; L300-L304 PolarHBondContact O-N 2.85Å; L300-L304 VanDerWaalsContact O-N 3.09Å; W302-L304 PolarHBondContact O-N 3.34Å; L304-F307 PolarHBondContact O-N 3.28Å; L304-I308 HydrophobicContact CD1-CD1 3.97Å; L304-I308 HydrophobicContact CD1-CG1 4.33Å; L304-I308 HydrophobicContact CG-CD1 3.89Å; L304-I308 WeakPolarHBondContact O-CG1 3.31Å; L304-I308 PolarHBondContact O-N 2.72Å
305	S	95.5	Very high	89.8	Confident	11 Å²	11	46 Å²	46	8%	0.077	22%	0.222	C	C	.	.	H	α-helix	trans	-62.3	-46.4	-179.1	-174.5	0	0	0	0	111.7	A76 S80 G301 W302 F307 I308 I309 L343	A76-S305 WeakPolarHBondContact O-CB 3.45Å; A76-S305 PolarHBondContact O-OG 3.48Å; S80-S305 WeakPolarHBondContact CB-OG 3.31Å; S80-S305 PolarHBondContact N-OG 3.2Å; G301-S305 WeakPolarHBondContact O-CB 2.98Å; G301-S305 PolarHBondContact O-N 3.08Å; W302-S305 PolarHBondContact O-N 3.37Å; S305-F307 VanDerWaalsContact C-N 3.29Å; S305-F307 PolarHBondContact O-N 3.21Å; S305-I308 PolarHBondContact O-N 2.83Å; S305-I309 WeakPolarHBondContact O-CB 3.47Å; S305-I309 VanDerWaalsContact O-CG1 3.31Å; S305-I309 WeakPolarHBondContact O-CG1 3.15Å; S305-I309 PolarHBondContact O-N 3.45Å; S305-L343 WeakPolarHBondContact OG-CD1 3.48Å
306	M	94.3	Very high	90	Very high	0 Å²	0	44 Å²	44	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-62.6	-36.3	177.8	-175.3	54.6	-152.6	0	0	112.2	G79 P83 L84 W302 G310 F437 G451 S454	G79-M306 WeakPolarHBondContact O-CA 3.35Å; G79-M306 WeakPolarHBondContact O-CB 3.47Å; P83-M306 HydrophobicContact CB-CE 4.23Å; P83-M306 HydrophobicContact CB-CG 4.48Å; P83-M306 HydrophobicContact CB-SD 3.73Å; P83-M306 HydrophobicContact CG-CG 4.23Å; P83-M306 HydrophobicContact CG-SD 3.76Å; L84-M306 HydrophobicContact CD1-CE 3.94Å; L84-M306 HydrophobicContact CD1-SD 4.06Å; L84-M306 HydrophobicContact CD2-CE 3.8Å; L84-M306 HydrophobicContact CG-CE 3.75Å; L84-M306 HydrophobicContact CG-SD 4.08Å; W302-M306 WeakPolarHBondContact O-CB 3.43Å; W302-M306 PolarHBondContact O-N 3.45Å; M306-G310 PolarHBondContact O-N 3.49Å; M306-F437 HydrophobicContact CE-CE2 3.83Å; M306-F437 HydrophobicContact CE-CZ 4.47Å; M306-G451 WeakPolarHBondContact O-CA 3.35Å; M306-S454 VanDerWaalsContact CG-CB 3.41Å; M306-S454 WeakPolarHBondContact CG-OG 3.23Å
307	F	94.7	Very high	89.2	Confident	73 Å²	73	43.5 Å²	43.5	32%	0.32	21%	0.214	S	C	.	.	H	α-helix	trans	-66	-48.8	175	-175.5	-112	0	0	0	112.6	G303 L304 S305 I309 G310 I311 L452 V455	G303-F307 WeakPolarHBondContact O-CB 3.41Å; G303-F307 PolarHBondContact O-N 3.35Å; G303-F307 VanDerWaalsContact O-N 3.12Å; L304-F307 PolarHBondContact O-N 3.28Å; S305-F307 VanDerWaalsContact C-N 3.29Å; S305-F307 PolarHBondContact O-N 3.21Å; F307-I309 VanDerWaalsContact C-N 3.34Å; F307-I309 PolarHBondContact O-N 3.43Å; F307-G310 PolarHBondContact O-N 3.48Å; F307-I311 HydrophobicContact CD1-CD1 4.07Å; F307-I311 HydrophobicContact CE1-CD1 3.56Å; F307-I311 HydrophobicContact CE2-CD1 4.17Å; F307-I311 HydrophobicContact CZ-CD1 3.63Å; F307-I311 PolarHBondContact O-N 3.46Å; F307-L452 HydrophobicContact CE2-CB 4.45Å; F307-L452 HydrophobicContact CE2-CD1 4.38Å; F307-V455 HydrophobicContact CB-CG2 3.68Å; F307-V455 HydrophobicContact CD2-CG2 4.12Å; F307-V455 HydrophobicContact CG-CG2 4.04Å
308	I	95.8	Very high	87.7	Confident	93 Å²	93	41.8 Å²	41.8	48%	0.477	21%	0.213	S	C	.	.	H	α-helix	trans	-60.3	-46.2	178.2	-68	168.7	0	0	0	110.3	L304 S305 I311 A312	L304-I308 HydrophobicContact CD1-CD1 3.97Å; L304-I308 HydrophobicContact CD1-CG1 4.33Å; L304-I308 HydrophobicContact CG-CD1 3.89Å; L304-I308 WeakPolarHBondContact O-CG1 3.31Å; L304-I308 PolarHBondContact O-N 2.72Å; S305-I308 PolarHBondContact O-N 2.83Å; I308-I311 PolarHBondContact O-N 2.99Å; I308-A312 VanDerWaalsContact O-CB 3.32Å; I308-A312 WeakPolarHBondContact O-CB 3.21Å; I308-A312 PolarHBondContact O-N 3.24Å
309	I	95.1	Very high	86.6	Confident	10 Å²	10	43.9 Å²	43.9	5%	0.051	22%	0.222	C	C	.	.	H	α-helix	trans	-66.9	-38.1	178.7	-66.7	-65.6	0	0	0	111.7	L84 S305 F307 I311 A312 L313 L335 C336 A339	L84-I309 HydrophobicContact CD1-CG2 3.88Å; S305-I309 WeakPolarHBondContact O-CB 3.47Å; S305-I309 VanDerWaalsContact O-CG1 3.31Å; S305-I309 WeakPolarHBondContact O-CG1 3.15Å; S305-I309 PolarHBondContact O-N 3.45Å; F307-I309 VanDerWaalsContact C-N 3.34Å; F307-I309 PolarHBondContact O-N 3.43Å; I309-I311 VanDerWaalsContact C-N 3.34Å; I309-I311 PolarHBondContact O-N 3.11Å; I309-A312 PolarHBondContact O-N 3.5Å; I309-L313 HydrophobicContact CG2-CD1 3.94Å; I309-L313 HydrophobicContact CG2-CG 4.14Å; I309-L313 WeakPolarHBondContact O-CB 3.32Å; I309-L313 WeakPolarHBondContact O-CG 3.44Å; I309-L313 PolarHBondContact O-N 3.32Å; I309-L335 HydrophobicContact CD1-CG 4.38Å; I309-C336 WeakPolarHBondContact CG2-SG 3.45Å; I309-A339 HydrophobicContact CD1-CB 3.5Å; I309-A339 HydrophobicContact CG1-CB 4.37Å
310	G	92.8	Very high	85.1	Confident	0 Å²	0	47.8 Å²	47.8	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-56	-47.6	173.2	0	0	0	0	0	112.2	M306 F307 D314 P447 S448	M306-G310 PolarHBondContact O-N 3.49Å; F307-G310 PolarHBondContact O-N 3.48Å; G310-D314 PolarHBondContact O-N 3.13Å; G310-P447 VanDerWaalsContact CA-O 3.32Å; G310-P447 WeakPolarHBondContact CA-O 3.35Å; G310-P447 CarbonylContact O-C 3.57Å; G310-P447 VanDerWaalsContact O-CB 3.26Å; G310-P447 WeakPolarHBondContact O-CB 3.44Å; G310-S448 PolarHBondContact O-N 3.11Å
311	I	92.4	Very high	83.9	Confident	59 Å²	59	48.3 Å²	48.3	30%	0.303	26%	0.259	S	S	.	.	H	α-helix	trans	-64.7	-48	175.4	-66.3	172.2	0	0	0	110.8	F307 I308 I309 L313 D314 Y315	F307-I311 HydrophobicContact CD1-CD1 4.07Å; F307-I311 HydrophobicContact CE1-CD1 3.56Å; F307-I311 HydrophobicContact CE2-CD1 4.17Å; F307-I311 HydrophobicContact CZ-CD1 3.63Å; F307-I311 PolarHBondContact O-N 3.46Å; I308-I311 PolarHBondContact O-N 2.99Å; I309-I311 VanDerWaalsContact C-N 3.34Å; I309-I311 PolarHBondContact O-N 3.11Å; I311-L313 VanDerWaalsContact C-N 3.28Å; I311-L313 PolarHBondContact O-N 3.33Å; I311-D314 WeakPolarHBondContact O-CB 3.41Å; I311-D314 PolarHBondContact O-N 2.94Å; I311-Y315 HydrophobicContact CG2-CD2 3.92Å; I311-Y315 HydrophobicContact CG2-CE2 3.77Å; I311-Y315 VanDerWaalsContact O-CD2 3.26Å; I311-Y315 WeakPolarHBondContact O-CD2 3.44Å; I311-Y315 PolarHBondContact O-N 3.5Å
312	A	92.2	Very high	83	Confident	34 Å²	34	49.1 Å²	49.1	28%	0.281	26%	0.263	S	S	.	.	H	α-helix	trans	-64.3	-34.6	-175.9	0	0	0	0	0	112.2	I308 I309 Y315 S316 L335	I308-A312 VanDerWaalsContact O-CB 3.32Å; I308-A312 WeakPolarHBondContact O-CB 3.21Å; I308-A312 PolarHBondContact O-N 3.24Å; I309-A312 PolarHBondContact O-N 3.5Å; A312-Y315 PolarHBondContact O-N 3.05Å; A312-S316 WeakPolarHBondContact O-CB 3.24Å; A312-S316 PolarHBondContact O-N 3.47Å; A312-L335 HydrophobicContact CB-CD2 3.51Å
313	L	90.1	Very high	82.1	Confident	0 Å²	0	48.9 Å²	48.9	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-66.3	-35.7	172.1	-77.3	175	0	0	0	112.5	L84 I309 I311 Y315 S316 K331 N332 Y333 P447	L84-L313 HydrophobicContact CD1-CD1 3.5Å; I309-L313 HydrophobicContact CG2-CD1 3.94Å; I309-L313 HydrophobicContact CG2-CG 4.14Å; I309-L313 WeakPolarHBondContact O-CB 3.32Å; I309-L313 WeakPolarHBondContact O-CG 3.44Å; I309-L313 PolarHBondContact O-N 3.32Å; I311-L313 VanDerWaalsContact C-N 3.28Å; I311-L313 PolarHBondContact O-N 3.33Å; L313-Y315 VanDerWaalsContact C-N 3.27Å; L313-Y315 PolarHBondContact O-N 3.03Å; L313-S316 WeakPolarHBondContact CA-OG 3.38Å; L313-S316 PolarHBondContact O-N 2.91Å; L313-S316 VanDerWaalsContact O-N 3.15Å; L313-S316 PolarHBondContact O-OG 3.42Å; L313-K331 HydrophobicContact CD2-CB 4.25Å; L313-K331 WeakPolarHBondContact O-CD 3.06Å; L313-N332 WeakPolarHBondContact CD2-O 3.34Å; L313-Y333 HydrophobicContact CD1-CD1 4.27Å; L313-Y333 HydrophobicContact CD1-CE1 3.9Å; L313-Y333 HydrophobicContact CD2-CD1 4.38Å; L313-P447 HydrophobicContact CB-CB 3.69Å; L313-P447 HydrophobicContact CB-CG 4.05Å; L313-P447 HydrophobicContact CD1-CB 4.37Å
314	D	86.2	Confident	81.4	Confident	34 Å²	34	49.5 Å²	49.5	18%	0.182	27%	0.27	C	S	.	.	H	α-helix	trans	-61.7	-37.6	175.4	-88.7	-20.5	0	0	0	112.2	G310 I311 L317 K331 S446 P447 S448	G310-D314 PolarHBondContact O-N 3.13Å; I311-D314 WeakPolarHBondContact O-CB 3.41Å; I311-D314 PolarHBondContact O-N 2.94Å; D314-L317 WeakPolarHBondContact O-CD2 3.35Å; D314-L317 WeakPolarHBondContact O-CG 3.44Å; D314-K331 PolarHBondContact O-NZ 3.24Å; D314-K331 IonicContact OD1-NZ 3.18Å; D314-S446 PolarHBondContact OD2-OG 3.47Å; D314-P447 WeakPolarHBondContact OD1-CD 3.39Å; D314-P447 WeakPolarHBondContact OD1-CG 3.29Å; D314-S448 WeakPolarHBondContact OD2-CB 3.15Å; D314-S448 PolarHBondContact OD2-N 3.02Å; D314-S448 PolarHBondContact OD2-OG 3.44Å
315	Y	84.2	Confident	80.4	Confident	189 Å²	189	47 Å²	47	74%	0.741	26%	0.263	S	S	*	.	H	α-helix	trans	-84.7	-6	175.3	-67.7	-75.5	0	0	0	114.6	I311 A312 L313 L317	I311-Y315 HydrophobicContact CG2-CD2 3.92Å; I311-Y315 HydrophobicContact CG2-CE2 3.77Å; I311-Y315 VanDerWaalsContact O-CD2 3.26Å; I311-Y315 WeakPolarHBondContact O-CD2 3.44Å; I311-Y315 PolarHBondContact O-N 3.5Å; A312-Y315 PolarHBondContact O-N 3.05Å; L313-Y315 VanDerWaalsContact C-N 3.27Å; L313-Y315 PolarHBondContact O-N 3.03Å; Y315-L317 PolarHBondContact O-N 3.4Å
316	S	79.3	Confident	79	Confident	18 Å²	18	48.6 Å²	48.6	13%	0.126	27%	0.27	C	S	.	.			trans	-75.1	34.2	-178.5	73.2	0	0	0	0	114.5	A312 L313 V318 N332	A312-S316 WeakPolarHBondContact O-CB 3.24Å; A312-S316 PolarHBondContact O-N 3.47Å; L313-S316 WeakPolarHBondContact CA-OG 3.38Å; L313-S316 PolarHBondContact O-N 2.91Å; L313-S316 VanDerWaalsContact O-N 3.15Å; L313-S316 PolarHBondContact O-OG 3.42Å; S316-V318 PolarHBondContact O-N 3.16Å; S316-V318 VanDerWaalsContact O-N 3.15Å; S316-N332 PolarHBondContact OG-N 2.81Å
317	L	62.7	Low	77.8	Confident	59 Å²	59	49 Å²	49	31%	0.309	27%	0.273	S	S	.	.			trans	-72.8	-4.8	-168.6	-60.1	177.3	0	0	0	114.9	D314 Y315 V328	D314-L317 WeakPolarHBondContact O-CD2 3.35Å; D314-L317 WeakPolarHBondContact O-CG 3.44Å; Y315-L317 PolarHBondContact O-N 3.4Å; L317-V328 HydrophobicContact CD1-CG1 4.5Å; L317-V328 HydrophobicContact CD2-CG1 4.05Å; L317-V328 WeakPolarHBondContact CD2-O 3.42Å
318	V	55.5	Low	76.5	Confident	57 Å²	57	48.3 Å²	48.3	35%	0.345	27%	0.274	S	S	.	.			trans	-122.8	105.4	-171.7	-178.8	0	0	0	0	110.1	M188 S316 P320	M188-V318 HydrophobicContact CE-CB 4.32Å; M188-V318 HydrophobicContact CE-CG1 3.44Å; M188-V318 VanDerWaalsContact CE-CG1 3.44Å; M188-V318 HydrophobicContact CE-CG2 3.9Å; M188-V318 HydrophobicContact SD-CG1 4.13Å; M188-V318 HydrophobicContact SD-CG2 3.62Å; S316-V318 PolarHBondContact O-N 3.16Å; S316-V318 VanDerWaalsContact O-N 3.15Å; V318-P320 WeakPolarHBondContact O-CD 3.34Å
319	F	64	Low	75.4	Confident	43 Å²	43	48.9 Å²	48.9	19%	0.189	28%	0.275	C	S	.	.			trans	-88.9	114.6	160.4	-64.4	-85.6	0	0	0	107.3	S321 H322 E330 N332	F319-S321 PolarHBondContact O-N 3.39Å; F319-H322 HydrophobicContact CB-CB 3.81Å; F319-H322 AromaticContact CD2-CD2 3.77Å; F319-H322 HydrophobicContact CG-CB 4.5Å; F319-E330 HydrophobicContact CE2-CB 4.12Å; F319-E330 HydrophobicContact CE2-CG 3.87Å; F319-E330 HydrophobicContact CZ-CG 4.01Å; F319-N332 HydrophobicContact CD1-CB 4.19Å; F319-N332 HydrophobicContact CE1-CB 3.49Å; F319-N332 VanDerWaalsContact CE1-CB 3.49Å; F319-N332 VanDerWaalsContact CE1-CG 3.48Å; F319-N332 HydrophobicContact CZ-CB 3.75Å
320	P	55.9	Low	74.7	Confident	105 Å²	105	48.5 Å²	48.5	68%	0.682	27%	0.273	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.5	-24.3	180	-25.8	34.8	0	0	0	113.8	V318	V318-P320 WeakPolarHBondContact O-CD 3.34Å
321	S	61.4	Low	74.4	Confident	107 Å²	107	49.6 Å²	49.6	75%	0.748	28%	0.277	S	S	*	.	T	Hydrogen-bonded Turn	trans	-135.4	48.3	-175.2	60.9	0	0	0	0	112.1	F319	F319-S321 PolarHBondContact O-N 3.39Å
322	H	73.8	Confident	74.2	Confident	16 Å²	16	48.7 Å²	48.7	7%	0.074	27%	0.273	C	S	.	.			trans	-69.8	127.2	175.1	-161.9	-105.5	0	0	0	110.8	K244 F319 C324 G325 E330	K244-H322 WeakPolarHBondContact CE-NE2 3.42Å; F319-H322 HydrophobicContact CB-CB 3.81Å; F319-H322 AromaticContact CD2-CD2 3.77Å; F319-H322 HydrophobicContact CG-CB 4.5Å; H322-C324 PolarHBondContact ND1-N 3.41Å; H322-C324 PolarHBondContact O-N 3.4Å; H322-G325 VanDerWaalsContact CB-O 3.27Å; H322-G325 WeakPolarHBondContact CB-O 3.16Å; H322-G325 VanDerWaalsContact CG-O 3.29Å; H322-G325 PolarHBondContact ND1-O 2.82Å; H322-G325 PolarHBondContact O-N 2.65Å; H322-G325 VanDerWaalsContact O-N 3.14Å; H322-E330 IonicContact CE1-OE2 2.82Å; H322-E330 IonicContact NE2-OE1 2.99Å; H322-E330 IonicContact NE2-OE2 3.29Å; H322-E330 PolarHBondContact NE2-OE2 3.42Å
323	P	75	Confident	74.1	Confident	35 Å²	35	47.2 Å²	47.2	23%	0.227	26%	0.261	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.6	-22.4	-177.6	21.3	-32.5	0	0	0	113.8	A168 M169 K244	A168-P323 HydrophobicContact CB-CB 3.87Å; M169-P323 PolarHBondContact N-O 3.42Å; K244-P323 HydrophobicContact CG-CG 4.46Å
324	C	76	Confident	74.1	Confident	18 Å²	18	50 Å²	50	12%	0.122	28%	0.278	C	S	.	.	T	Hydrogen-bonded Turn	trans	-111.1	20.1	-177.5	-54.9	0	0	0	0	113.8	C155 K243 H322	C155-C324 HydrophobicContact CB-CB 3.61Å; C155-C324 WeakPolarHBondContact CB-SG 3.49Å; C155-C324 WeakPolarHBondContact SG-CA 3.35Å; C155-C324 WeakPolarHBondContact SG-CB 3.35Å; C155-C324 CovalentContact SG-SG 2.02Å; C155-C324 PolarHBondContact SG-SG 2.66Å; K243-C324 HydrophobicContact CB-CB 3.99Å; H322-C324 PolarHBondContact ND1-N 3.41Å; H322-C324 PolarHBondContact O-N 3.4Å
325	G	71.4	Confident	74.4	Confident	26 Å²	26	51.5 Å²	51.5	27%	0.268	29%	0.285	S	S	.	.	S	Bend	trans	69	-163.2	-174.7	0	0	0	0	0	113.2	H322 N327	H322-G325 VanDerWaalsContact CB-O 3.27Å; H322-G325 WeakPolarHBondContact CB-O 3.16Å; H322-G325 VanDerWaalsContact CG-O 3.29Å; H322-G325 PolarHBondContact ND1-O 2.82Å; H322-G325 PolarHBondContact O-N 2.65Å; H322-G325 VanDerWaalsContact O-N 3.14Å; G325-N327 PolarHBondContact O-N 2.96Å
326	L	67.3	Low	74.9	Confident	44 Å²	44	42.5 Å²	42.5	23%	0.23	25%	0.25	C	S	.	.			trans	-63.2	129.1	-175.1	-167.4	71.3	0	0	0	111	K243	K243-L326 WeakPolarHBondContact CE-O 3.29Å; K243-L326 PolarHBondContact NZ-O 2.92Å
327	N	67.7	Low	75.6	Confident	9 Å²	9	41.7 Å²	41.7	5%	0.048	24%	0.244	C	C	.	.			trans	-137.1	104.3	174.8	-175.6	4.6	0	0	0	110.5	S242 K243 G325 Q329 E330	S242-N327 WeakPolarHBondContact CA-ND2 3.47Å; K243-N327 HydrophobicContact CD-CB 4.06Å; K243-N327 HydrophobicContact CG-CB 4.3Å; K243-N327 PolarHBondContact N-ND2 2.82Å; K243-N327 VanDerWaalsContact N-ND2 3.15Å; G325-N327 PolarHBondContact O-N 2.96Å; N327-Q329 VanDerWaalsContact C-N 3.29Å; N327-Q329 PolarHBondContact O-N 3.24Å; N327-Q329 PolarHBondContact OD1-N 3.35Å; N327-E330 HydrophobicContact CB-CB 4.28Å; N327-E330 WeakPolarHBondContact ND2-CB 3.25Å; N327-E330 PolarHBondContact ND2-OE2 3.45Å; N327-E330 PolarHBondContact O-N 3.23Å
328	V	67	Low	77.2	Confident	58 Å²	58	40.8 Å²	40.8	35%	0.352	25%	0.245	S	C	.	.	T	Hydrogen-bonded Turn	trans	-70.4	-24.4	-173.2	-172.1	0	0	0	0	112.8	Y192 L317	Y192-V328 HydrophobicContact CD2-CG2 4.13Å; Y192-V328 HydrophobicContact CE2-CG1 4.48Å; Y192-V328 HydrophobicContact CE2-CG2 4.13Å; L317-V328 HydrophobicContact CD1-CG1 4.5Å; L317-V328 HydrophobicContact CD2-CG1 4.05Å; L317-V328 WeakPolarHBondContact CD2-O 3.42Å
329	Q	73.6	Confident	79.1	Confident	106 Å²	106	38.9 Å²	38.9	50%	0.495	24%	0.236	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84.9	-24.6	-177.5	-67.3	-174.3	-15.2	0	0	113.1	H241 N327	H241-Q329 HydrophobicContact CB-CB 4.39Å; H241-Q329 CarbonylContact O-C 3.45Å; N327-Q329 VanDerWaalsContact C-N 3.29Å; N327-Q329 PolarHBondContact O-N 3.24Å; N327-Q329 PolarHBondContact OD1-N 3.35Å
330	E	80.5	Confident	80.7	Confident	1 Å²	1	36.9 Å²	36.9	1%	0.005	23%	0.227	C	C	.	.			trans	-80.8	135.7	179.6	-170.3	167.6	167.6	0	0	110.4	Q91 S242 K244 F319 H322 N327	Q91-E330 HydrophobicContact CG-CG 4.23Å; S242-E330 WeakPolarHBondContact CB-OE2 3.5Å; S242-E330 PolarHBondContact OG-OE2 2.91Å; K244-E330 WeakPolarHBondContact CE-OE1 3.44Å; K244-E330 IonicContact NZ-OE1 2.65Å; K244-E330 PolarHBondContact NZ-OE1 3.31Å; F319-E330 HydrophobicContact CE2-CB 4.12Å; F319-E330 HydrophobicContact CE2-CG 3.87Å; F319-E330 HydrophobicContact CZ-CG 4.01Å; H322-E330 IonicContact CE1-OE2 2.82Å; H322-E330 IonicContact NE2-OE1 2.99Å; H322-E330 IonicContact NE2-OE2 3.29Å; H322-E330 PolarHBondContact NE2-OE2 3.42Å; N327-E330 HydrophobicContact CB-CB 4.28Å; N327-E330 WeakPolarHBondContact ND2-CB 3.25Å; N327-E330 PolarHBondContact ND2-OE2 3.45Å; N327-E330 PolarHBondContact O-N 3.23Å
331	K	86.2	Confident	82.6	Confident	23 Å²	23	32.4 Å²	32.4	10%	0.1	20%	0.198	C	C	.	.			trans	-111.8	144.9	-176.1	-56.9	-52.9	-164.6	175.6	0	110.7	Q91 L313 D314 Y333 P447	Q91-K331 PolarHBondContact NE2-O 3.27Å; Q91-K331 PolarHBondContact OE1-O 2.97Å; L313-K331 HydrophobicContact CD2-CB 4.25Å; L313-K331 WeakPolarHBondContact O-CD 3.06Å; D314-K331 PolarHBondContact O-NZ 3.24Å; D314-K331 IonicContact OD1-NZ 3.18Å; K331-Y333 HydrophobicContact CB-CE2 4.15Å; K331-Y333 PolarHBondContact O-N 2.83Å; K331-P447 HydrophobicContact CD-CG 4.49Å; K331-P447 HydrophobicContact CG-CG 4.13Å
332	N	88	Confident	84.3	Confident	40 Å²	40	32.7 Å²	32.7	21%	0.214	19%	0.19	C	C	.	.			trans	-86.6	87.7	-178.5	-168.8	-2.9	0	0	0	111.6	L313 S316 F319 T334 L335	L313-N332 WeakPolarHBondContact CD2-O 3.34Å; S316-N332 PolarHBondContact OG-N 2.81Å; F319-N332 HydrophobicContact CD1-CB 4.19Å; F319-N332 HydrophobicContact CE1-CB 3.49Å; F319-N332 VanDerWaalsContact CE1-CB 3.49Å; F319-N332 VanDerWaalsContact CE1-CG 3.48Å; F319-N332 HydrophobicContact CZ-CB 3.75Å; N332-T334 PolarHBondContact O-N 3.46Å; N332-T334 WeakPolarHBondContact OD1-CB 3.32Å; N332-T334 PolarHBondContact OD1-N 3.39Å; N332-T334 PolarHBondContact OD1-OG1 3.18Å; N332-L335 WeakPolarHBondContact O-CB 3.29Å; N332-L335 PolarHBondContact O-N 3.28Å
333	Y	91.3	Very high	85.5	Confident	4 Å²	4	33.7 Å²	33.7	2%	0.016	20%	0.196	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.6	-12.9	178.9	-72.3	-75.6	0	0	0	114.5	L84 I87 Y88 L313 K331 L335 C336 F337	L84-Y333 HydrophobicContact CB-CD1 4.47Å; L84-Y333 HydrophobicContact CB-CE1 4.01Å; L84-Y333 HydrophobicContact CD1-CE1 4.41Å; L84-Y333 HydrophobicContact CD2-CE1 4.49Å; I87-Y333 HydrophobicContact CG2-CE2 4.43Å; I87-Y333 WeakPolarHBondContact CG2-OH 3.46Å; Y88-Y333 HydrophobicContact CD2-CD2 4.03Å; Y88-Y333 AromaticContact CD2-CG 3.96Å; Y88-Y333 HydrophobicContact CD2-CG 3.96Å; Y88-Y333 HydrophobicContact CG-CG 4.46Å; L313-Y333 HydrophobicContact CD1-CD1 4.27Å; L313-Y333 HydrophobicContact CD1-CE1 3.9Å; L313-Y333 HydrophobicContact CD2-CD1 4.38Å; K331-Y333 HydrophobicContact CB-CE2 4.15Å; K331-Y333 PolarHBondContact O-N 2.83Å; Y333-L335 PolarHBondContact O-N 3.44Å; Y333-L335 VanDerWaalsContact O-N 3.09Å; Y333-C336 WeakPolarHBondContact O-CA 3.45Å; Y333-C336 VanDerWaalsContact O-CB 3.24Å; Y333-C336 WeakPolarHBondContact O-CB 3.45Å; Y333-C336 PolarHBondContact O-N 2.92Å; Y333-F337 VanDerWaalsContact O-CD2 3.3Å; Y333-F337 WeakPolarHBondContact O-CD2 3.43Å; Y333-F337 PolarHBondContact O-N 3.44Å
334	T	89.9	Confident	86.5	Confident	58 Å²	58	32 Å²	32	36%	0.356	19%	0.185	S	C	.	.	H	α-helix	trans	-50.5	-34.4	168.9	-43.5	0	0	0	0	110.8	D146 N332 C336 F337 A338	D146-T334 WeakPolarHBondContact OD2-CG2 3.35Å; N332-T334 PolarHBondContact O-N 3.46Å; N332-T334 WeakPolarHBondContact OD1-CB 3.32Å; N332-T334 PolarHBondContact OD1-N 3.39Å; N332-T334 PolarHBondContact OD1-OG1 3.18Å; T334-C336 VanDerWaalsContact C-N 3.29Å; T334-C336 PolarHBondContact O-N 3.43Å; T334-F337 PolarHBondContact O-N 3.01Å; T334-A338 WeakPolarHBondContact O-CB 3.29Å; T334-A338 PolarHBondContact O-N 3.29Å
335	L	91.7	Very high	87.6	Confident	66 Å²	66	33.6 Å²	33.6	35%	0.346	20%	0.196	S	C	.	.	H	α-helix	trans	-59.7	-38.5	175.1	-177.2	64.6	0	0	0	112.7	I309 A312 N332 Y333 A339	I309-L335 HydrophobicContact CD1-CG 4.38Å; A312-L335 HydrophobicContact CB-CD2 3.51Å; N332-L335 WeakPolarHBondContact O-CB 3.29Å; N332-L335 PolarHBondContact O-N 3.28Å; Y333-L335 PolarHBondContact O-N 3.44Å; Y333-L335 VanDerWaalsContact O-N 3.09Å; L335-A339 VanDerWaalsContact O-CB 3.23Å; L335-A339 WeakPolarHBondContact O-CB 3.47Å; L335-A339 PolarHBondContact O-N 2.92Å
336	C	94.5	Very high	88.8	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-68.3	-43	177.9	-57.9	0	0	0	0	111	S80 L81 I309 Y333 T334 A339 F340	S80-C336 WeakPolarHBondContact O-CB 3.21Å; L81-C336 HydrophobicContact CB-CB 4.48Å; L81-C336 HydrophobicContact CD1-CB 3.77Å; I309-C336 WeakPolarHBondContact CG2-SG 3.45Å; Y333-C336 WeakPolarHBondContact O-CA 3.45Å; Y333-C336 VanDerWaalsContact O-CB 3.24Å; Y333-C336 WeakPolarHBondContact O-CB 3.45Å; Y333-C336 PolarHBondContact O-N 2.92Å; T334-C336 VanDerWaalsContact C-N 3.29Å; T334-C336 PolarHBondContact O-N 3.43Å; C336-A339 PolarHBondContact O-N 3.43Å; C336-F340 WeakPolarHBondContact O-CB 3.36Å; C336-F340 PolarHBondContact O-N 2.72Å
337	F	95.3	Very high	90.2	Very high	0 Å²	0	32.1 Å²	32.1	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-65.5	-41.2	176.7	-70.5	-78	0	0	0	112.3	L81 Y88 T142 M145 D146 Y333 T334 S341	L81-F337 HydrophobicContact CD1-CD1 4.07Å; L81-F337 HydrophobicContact CD1-CD2 4.33Å; L81-F337 HydrophobicContact CD1-CE1 3.87Å; L81-F337 HydrophobicContact CD1-CE2 4.13Å; L81-F337 HydrophobicContact CD1-CG 4.28Å; L81-F337 HydrophobicContact CD1-CZ 3.89Å; L81-F337 HydrophobicContact CD2-CD1 3.78Å; L81-F337 HydrophobicContact CD2-CE1 3.77Å; L81-F337 HydrophobicContact CG-CE1 4.46Å; Y88-F337 AromaticContact CD1-CE2 3.99Å; Y88-F337 HydrophobicContact CD1-CE2 3.99Å; Y88-F337 AromaticContact CD1-CZ 3.76Å; Y88-F337 HydrophobicContact CD1-CZ 3.76Å; Y88-F337 HydrophobicContact CD2-CE2 4.12Å; Y88-F337 AromaticContact CE1-CE2 3.77Å; Y88-F337 HydrophobicContact CE1-CE2 3.77Å; Y88-F337 AromaticContact CE1-CZ 3.53Å; Y88-F337 HydrophobicContact CE1-CZ 3.53Å; Y88-F337 AromaticContact CE2-CE2 3.9Å; Y88-F337 HydrophobicContact CE2-CE2 3.9Å; Y88-F337 HydrophobicContact CG-CE2 4.15Å; Y88-F337 HydrophobicContact CG-CZ 4.34Å; Y88-F337 AromaticContact CZ-CE2 3.7Å; Y88-F337 AromaticContact CZ-CZ 3.92Å; T142-F337 HydrophobicContact CG2-CD1 3.7Å; T142-F337 HydrophobicContact CG2-CE1 4.22Å; T142-F337 VanDerWaalsContact O-CD1 3.29Å; T142-F337 WeakPolarHBondContact O-CD1 3.29Å; M145-F337 HydrophobicContact CB-CE1 3.84Å; M145-F337 HydrophobicContact CB-CZ 4.37Å; D146-F337 HydrophobicContact CB-CB 3.9Å; D146-F337 HydrophobicContact CB-CD1 3.97Å; D146-F337 HydrophobicContact CB-CD2 3.87Å; D146-F337 HydrophobicContact CB-CE1 4.48Å; D146-F337 HydrophobicContact CB-CE2 4.4Å; D146-F337 HydrophobicContact CB-CG 3.65Å; D146-F337 WeakPolarHBondContact OD1-CD2 3.45Å; Y333-F337 VanDerWaalsContact O-CD2 3.3Å; Y333-F337 WeakPolarHBondContact O-CD2 3.43Å; Y333-F337 PolarHBondContact O-N 3.44Å; T334-F337 PolarHBondContact O-N 3.01Å; F337-S341 WeakPolarHBondContact O-CB 3.4Å; F337-S341 PolarHBondContact O-N 2.8Å; F337-S341 PolarHBondContact O-OG 2.89Å
338	A	94.3	Very high	91.6	Very high	41 Å²	41	34.1 Å²	34.1	34%	0.339	19%	0.194	S	C	.	.	H	α-helix	trans	-64.2	-47.4	174.5	0	0	0	0	0	111.5	T334 F340 S341 I342	T334-A338 WeakPolarHBondContact O-CB 3.29Å; T334-A338 PolarHBondContact O-N 3.29Å; A338-F340 PolarHBondContact O-N 3.27Å; A338-S341 PolarHBondContact O-N 3.25Å; A338-I342 VanDerWaalsContact O-CG1 3.31Å; A338-I342 WeakPolarHBondContact O-CG1 3.4Å; A338-I342 PolarHBondContact O-N 3.14Å
339	A	96	Very high	92.9	Very high	17 Å²	17	36.2 Å²	36.2	14%	0.14	20%	0.202	C	C	.	.	H	α-helix	trans	-60.9	-44.3	177.1	0	0	0	0	0	112	I309 L335 C336 S341 I342 L343	I309-A339 HydrophobicContact CD1-CB 3.5Å; I309-A339 HydrophobicContact CG1-CB 4.37Å; L335-A339 VanDerWaalsContact O-CB 3.23Å; L335-A339 WeakPolarHBondContact O-CB 3.47Å; L335-A339 PolarHBondContact O-N 2.92Å; C336-A339 PolarHBondContact O-N 3.43Å; A339-S341 VanDerWaalsContact C-N 3.32Å; A339-S341 PolarHBondContact O-N 3.47Å; A339-I342 PolarHBondContact O-N 2.68Å; A339-L343 WeakPolarHBondContact O-CB 3.43Å; A339-L343 WeakPolarHBondContact O-CD1 3.12Å; A339-L343 VanDerWaalsContact O-CG 3.25Å; A339-L343 WeakPolarHBondContact O-CG 3.47Å; A339-L343 PolarHBondContact O-N 2.88Å
340	F	97.3	Very high	93.9	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-55.3	-49.4	174.1	-178.3	-82	0	0	0	110.9	A77 S80 L81 F82 W138 T142 C336 A338 I342 L343 M344	A77-F340 VanDerWaalsContact C-CD2 3.45Å; A77-F340 HydrophobicContact CB-CD2 3.94Å; A77-F340 HydrophobicContact CB-CE2 3.96Å; A77-F340 HydrophobicContact CB-CG 4.34Å; A77-F340 HydrophobicContact CB-CZ 4.46Å; A77-F340 WeakPolarHBondContact O-CD2 3.17Å; S80-F340 VanDerWaalsContact OG-CA 3.31Å; S80-F340 WeakPolarHBondContact OG-CA 3.28Å; S80-F340 PolarHBondContact OG-N 3.28Å; L81-F340 HydrophobicContact CB-CB 4.22Å; L81-F340 HydrophobicContact CB-CD2 4.06Å; L81-F340 HydrophobicContact CB-CG 4.49Å; L81-F340 HydrophobicContact CD2-CB 4.27Å; L81-F340 HydrophobicContact CD2-CD2 4.14Å; L81-F340 HydrophobicContact CD2-CG 4.19Å; F82-F340 HydrophobicContact CD2-CD2 4.46Å; F82-F340 HydrophobicContact CD2-CE2 4.05Å; F82-F340 HydrophobicContact CE2-CD2 4.19Å; F82-F340 AromaticContact CE2-CE2 3.55Å; F82-F340 HydrophobicContact CE2-CE2 3.55Å; F82-F340 HydrophobicContact CE2-CZ 4.17Å; W138-F340 HydrophobicContact CB-CE1 4.48Å; W138-F340 HydrophobicContact CD2-CZ 4.47Å; W138-F340 AromaticContact CE3-CZ 3.92Å; W138-F340 HydrophobicContact CE3-CZ 3.92Å; T142-F340 HydrophobicContact CG2-CB 4.32Å; T142-F340 HydrophobicContact CG2-CD1 3.44Å; T142-F340 VanDerWaalsContact CG2-CD1 3.44Å; T142-F340 HydrophobicContact CG2-CE1 3.87Å; T142-F340 HydrophobicContact CG2-CG 3.85Å; T142-F340 VanDerWaalsContact OG1-CE1 3.3Å; T142-F340 WeakPolarHBondContact OG1-CE1 3.45Å; C336-F340 WeakPolarHBondContact O-CB 3.36Å; C336-F340 PolarHBondContact O-N 2.72Å; A338-F340 PolarHBondContact O-N 3.27Å; F340-I342 PolarHBondContact O-N 3.13Å; F340-L343 PolarHBondContact O-N 2.85Å; F340-M344 HydrophobicContact CD1-CB 4.36Å; F340-M344 HydrophobicContact CE1-CB 4.12Å; F340-M344 HydrophobicContact CE1-CE 4.13Å; F340-M344 HydrophobicContact CE1-CG 4.3Å; F340-M344 HydrophobicContact CE2-CE 4.14Å; F340-M344 HydrophobicContact CZ-CE 3.56Å; F340-M344 WeakPolarHBondContact O-CB 3.23Å; F340-M344 PolarHBondContact O-N 3.35Å
341	S	96.5	Very high	94.5	Very high	12 Å²	12	33.1 Å²	33.1	8%	0.084	19%	0.188	C	C	.	.	H	α-helix	trans	-65.7	-40.6	-176.2	-58.1	0	0	0	0	112.4	L143 F337 A338 A339 S345	L143-S341 VanDerWaalsContact CD2-OG 3.26Å; L143-S341 WeakPolarHBondContact CD2-OG 3.34Å; L143-S341 WeakPolarHBondContact CG-OG 3.39Å; F337-S341 WeakPolarHBondContact O-CB 3.4Å; F337-S341 PolarHBondContact O-N 2.8Å; F337-S341 PolarHBondContact O-OG 2.89Å; A338-S341 PolarHBondContact O-N 3.25Å; A339-S341 VanDerWaalsContact C-N 3.32Å; A339-S341 PolarHBondContact O-N 3.47Å; S341-S345 VanDerWaalsContact O-CB 3.31Å; S341-S345 WeakPolarHBondContact O-CB 3.26Å; S341-S345 PolarHBondContact O-N 3.03Å; S341-S345 PolarHBondContact O-OG 3.35Å
342	I	97.4	Very high	94.8	Very high	113 Å²	113	34 Å²	34	58%	0.579	20%	0.195	S	C	*	.	H	α-helix	trans	-65.8	-49.5	176.3	-67	165.9	0	0	0	110.5	A338 A339 F340 M344 S345 C346	A338-I342 VanDerWaalsContact O-CG1 3.31Å; A338-I342 WeakPolarHBondContact O-CG1 3.4Å; A338-I342 PolarHBondContact O-N 3.14Å; A339-I342 PolarHBondContact O-N 2.68Å; F340-I342 PolarHBondContact O-N 3.13Å; I342-M344 PolarHBondContact O-N 2.78Å; I342-S345 WeakPolarHBondContact O-CB 3.27Å; I342-S345 PolarHBondContact O-N 2.79Å; I342-C346 PolarHBondContact O-N 3.38Å; I342-C346 PolarHBondContact O-SG 2.87Å
343	L	97.8	Very high	94.9	Very high	36 Å²	36	37.7 Å²	37.7	19%	0.188	21%	0.211	C	C	.	.	H	α-helix	trans	-65.6	-39.5	-179.3	-69.2	167.4	0	0	0	111.8	F73 A76 A77 S305 A339 F340 S345 C346 A347	F73-L343 HydrophobicContact CD1-CD2 4.07Å; A76-L343 HydrophobicContact CB-CD1 4.05Å; A76-L343 HydrophobicContact CB-CD2 4.22Å; A77-L343 HydrophobicContact CB-CB 3.77Å; S305-L343 WeakPolarHBondContact OG-CD1 3.48Å; A339-L343 WeakPolarHBondContact O-CB 3.43Å; A339-L343 WeakPolarHBondContact O-CD1 3.12Å; A339-L343 VanDerWaalsContact O-CG 3.25Å; A339-L343 WeakPolarHBondContact O-CG 3.47Å; A339-L343 PolarHBondContact O-N 2.88Å; F340-L343 PolarHBondContact O-N 2.85Å; L343-S345 VanDerWaalsContact C-N 3.32Å; L343-C346 WeakPolarHBondContact O-CB 3.36Å; L343-C346 PolarHBondContact O-N 3.4Å; L343-A347 PolarHBondContact O-N 2.96Å
344	M	97.6	Very high	94.6	Very high	0 Å²	0	37.5 Å²	37.5	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-68.4	-32.9	175.6	-169.4	58.8	74.2	0	0	111.6	F74 A77 F78 L135 W138 I139 F340 I342 A347 F348	F74-M344 HydrophobicContact CD2-CE 3.87Å; F74-M344 HydrophobicContact CD2-SD 3.81Å; F74-M344 HydrophobicContact CE2-CE 3.97Å; F74-M344 HydrophobicContact CE2-SD 4.16Å; A77-M344 HydrophobicContact CB-CB 4.03Å; A77-M344 HydrophobicContact CB-CE 3.83Å; F78-M344 HydrophobicContact CD2-CE 4.36Å; F78-M344 HydrophobicContact CE2-CE 4.01Å; L135-M344 HydrophobicContact CD2-SD 3.6Å; W138-M344 HydrophobicContact CB-CE 4.29Å; W138-M344 HydrophobicContact CB-CG 4.16Å; W138-M344 HydrophobicContact CB-SD 4.46Å; W138-M344 HydrophobicContact CG-CE 4.22Å; I139-M344 HydrophobicContact CD1-CB 4.41Å; I139-M344 HydrophobicContact CD1-CG 4.14Å; I139-M344 HydrophobicContact CG1-CB 3.87Å; I139-M344 HydrophobicContact CG1-CG 3.6Å; F340-M344 HydrophobicContact CD1-CB 4.36Å; F340-M344 HydrophobicContact CE1-CB 4.12Å; F340-M344 HydrophobicContact CE1-CE 4.13Å; F340-M344 HydrophobicContact CE1-CG 4.3Å; F340-M344 HydrophobicContact CE2-CE 4.14Å; F340-M344 HydrophobicContact CZ-CE 3.56Å; F340-M344 WeakPolarHBondContact O-CB 3.23Å; F340-M344 PolarHBondContact O-N 3.35Å; I342-M344 PolarHBondContact O-N 2.78Å; M344-A347 WeakPolarHBondContact O-CB 3.38Å; M344-A347 PolarHBondContact O-N 3.07Å; M344-A347 HydrophobicContact SD-CB 4.16Å; M344-F348 WeakPolarHBondContact O-CB 3.45Å; M344-F348 PolarHBondContact O-N 3.11Å
345	S	97.6	Very high	94	Very high	51 Å²	51	42 Å²	42	36%	0.357	22%	0.221	S	C	.	.	H	α-helix	trans	-64.7	-39.8	171	-60.8	0	0	0	0	111.6	S341 I342 L343 F348 L349	S341-S345 VanDerWaalsContact O-CB 3.31Å; S341-S345 WeakPolarHBondContact O-CB 3.26Å; S341-S345 PolarHBondContact O-N 3.03Å; S341-S345 PolarHBondContact O-OG 3.35Å; I342-S345 WeakPolarHBondContact O-CB 3.27Å; I342-S345 PolarHBondContact O-N 2.79Å; L343-S345 VanDerWaalsContact C-N 3.32Å; S345-F348 WeakPolarHBondContact O-CB 3.26Å; S345-F348 PolarHBondContact O-N 3.01Å; S345-L349 WeakPolarHBondContact O-CG 3.37Å; S345-L349 PolarHBondContact O-N 2.71Å
346	C	97.3	Very high	93.2	Very high	40 Å²	40	41.6 Å²	41.6	27%	0.27	22%	0.217	S	C	.	.	H	α-helix	trans	-61.9	-42	170.9	-66.5	0	0	0	0	111.8	F73 I342 L343 F348 L349 M350	F73-C346 HydrophobicContact CB-CB 4.16Å; F73-C346 HydrophobicContact CD1-CB 3.71Å; F73-C346 HydrophobicContact CD2-CB 3.94Å; F73-C346 HydrophobicContact CE1-CB 4.04Å; F73-C346 HydrophobicContact CE2-CB 4.25Å; F73-C346 HydrophobicContact CG-CB 3.67Å; F73-C346 HydrophobicContact CZ-CB 4.3Å; I342-C346 PolarHBondContact O-N 3.38Å; I342-C346 PolarHBondContact O-SG 2.87Å; L343-C346 WeakPolarHBondContact O-CB 3.36Å; L343-C346 PolarHBondContact O-N 3.4Å; C346-F348 VanDerWaalsContact C-N 3.35Å; C346-L349 PolarHBondContact O-N 3.29Å; C346-M350 WeakPolarHBondContact O-CG 3.49Å; C346-M350 PolarHBondContact O-N 3.36Å
347	A	96.5	Very high	91.6	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-63	-40.5	174.8	0	0	0	0	0	111.9	F70 F73 F74 L343 M344 M350 A351	F70-A347 HydrophobicContact CD2-CB 4.36Å; F70-A347 WeakPolarHBondContact CD2-O 3.3Å; F70-A347 HydrophobicContact CE2-CB 4.35Å; F73-A347 HydrophobicContact CB-CB 3.9Å; F74-A347 HydrophobicContact CB-CB 4.11Å; L343-A347 PolarHBondContact O-N 2.96Å; M344-A347 WeakPolarHBondContact O-CB 3.38Å; M344-A347 PolarHBondContact O-N 3.07Å; M344-A347 HydrophobicContact SD-CB 4.16Å; A347-M350 PolarHBondContact O-N 2.91Å; A347-A351 WeakPolarHBondContact O-CB 3.33Å; A347-A351 PolarHBondContact O-N 3.41Å
348	F	96.7	Very high	89.5	Confident	51 Å²	51	57.7 Å²	57.7	22%	0.224	29%	0.292	C	S	.	.	H	α-helix	trans	-58	-47.4	172.5	176.2	-87.1	0	0	0	111.4	L132 L135 I136 M344 S345 C346 M350 A351 T352	L132-F348 HydrophobicContact CB-CE2 3.88Å; L132-F348 HydrophobicContact CD2-CD2 3.94Å; L132-F348 HydrophobicContact CD2-CE2 3.71Å; L132-F348 HydrophobicContact CD2-CZ 4.13Å; L132-F348 HydrophobicContact CG-CE2 4.31Å; L135-F348 HydrophobicContact CB-CB 4.45Å; L135-F348 HydrophobicContact CB-CD2 3.97Å; L135-F348 HydrophobicContact CD1-CB 4.43Å; L135-F348 HydrophobicContact CD1-CD2 4.48Å; I136-F348 HydrophobicContact CD1-CE2 3.75Å; I136-F348 HydrophobicContact CD1-CZ 4.22Å; I136-F348 HydrophobicContact CG1-CD2 4.09Å; I136-F348 HydrophobicContact CG1-CE2 3.62Å; I136-F348 HydrophobicContact CG1-CZ 4.38Å; M344-F348 WeakPolarHBondContact O-CB 3.45Å; M344-F348 PolarHBondContact O-N 3.11Å; S345-F348 WeakPolarHBondContact O-CB 3.26Å; S345-F348 PolarHBondContact O-N 3.01Å; C346-F348 VanDerWaalsContact C-N 3.35Å; F348-M350 VanDerWaalsContact C-N 3.31Å; F348-M350 PolarHBondContact O-N 3.01Å; F348-A351 WeakPolarHBondContact O-CB 3.48Å; F348-A351 PolarHBondContact O-N 3.49Å; F348-A351 VanDerWaalsContact O-N 3.13Å; F348-T352 HydrophobicContact CD1-CG2 4.23Å; F348-T352 HydrophobicContact CE1-CG2 3.94Å; F348-T352 HydrophobicContact CZ-CG2 4.44Å; F348-T352 WeakPolarHBondContact O-CG2 3.14Å; F348-T352 PolarHBondContact O-N 3Å
349	L	95.7	Very high	87.2	Confident	102 Å²	102	61.9 Å²	61.9	53%	0.534	30%	0.3	S	S	.	.	H	α-helix	trans	-59.2	-41.2	176	-68.2	174.9	0	0	0	111.7	S345 C346 T352	S345-L349 WeakPolarHBondContact O-CG 3.37Å; S345-L349 PolarHBondContact O-N 2.71Å; C346-L349 PolarHBondContact O-N 3.29Å; L349-T352 PolarHBondContact O-N 3.29Å; L349-T352 PolarHBondContact O-OG1 3.12Å
350	M	94.2	Very high	84.5	Confident	42 Å²	42	63.2 Å²	63.2	21%	0.207	32%	0.315	C	S	.	.	H	α-helix	trans	-66.3	-40.7	174.5	-63.5	-58.6	93.9	0	0	112.1	V66 L69 F70 F73 C346 A347 F348 T352 Q353	V66-M350 HydrophobicContact CG1-CB 4.47Å; V66-M350 WeakPolarHBondContact CG1-O 3.35Å; L69-M350 HydrophobicContact CB-CG 4.03Å; L69-M350 HydrophobicContact CB-SD 3.84Å; L69-M350 HydrophobicContact CD1-SD 4.04Å; F70-M350 HydrophobicContact CB-CB 3.94Å; F70-M350 HydrophobicContact CD2-CB 4.46Å; F73-M350 HydrophobicContact CD2-CG 4.03Å; F73-M350 HydrophobicContact CE2-CG 4.41Å; C346-M350 WeakPolarHBondContact O-CG 3.49Å; C346-M350 PolarHBondContact O-N 3.36Å; A347-M350 PolarHBondContact O-N 2.91Å; F348-M350 VanDerWaalsContact C-N 3.31Å; F348-M350 PolarHBondContact O-N 3.01Å; M350-T352 PolarHBondContact O-N 3.44Å; M350-Q353 WeakPolarHBondContact O-CB 3.17Å; M350-Q353 PolarHBondContact O-N 3.13Å
351	A	92.9	Very high	81.7	Confident	0 Å²	0	69.4 Å²	69.4	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-63	-27.6	175.9	0	0	0	0	0	112.7	F70 L131 L132 L135 A347 F348 Q353 F354	F70-A351 HydrophobicContact CD2-CB 4.03Å; F70-A351 HydrophobicContact CE2-CB 3.96Å; L131-A351 HydrophobicContact CD2-CB 3.99Å; L131-A351 HydrophobicContact CG-CB 4.29Å; L132-A351 HydrophobicContact CD2-CB 3.93Å; L135-A351 HydrophobicContact CD1-CB 3.49Å; L135-A351 VanDerWaalsContact CD1-CB 3.49Å; A347-A351 WeakPolarHBondContact O-CB 3.33Å; A347-A351 PolarHBondContact O-N 3.41Å; F348-A351 WeakPolarHBondContact O-CB 3.48Å; F348-A351 PolarHBondContact O-N 3.49Å; F348-A351 VanDerWaalsContact O-N 3.13Å; A351-Q353 PolarHBondContact O-N 3.44Å; A351-F354 WeakPolarHBondContact O-CB 3.44Å; A351-F354 PolarHBondContact O-N 3.5Å; A351-F354 VanDerWaalsContact O-N 3.15Å
352	T	92.2	Very high	78.9	Confident	41 Å²	41	70.4 Å²	70.4	25%	0.252	36%	0.361	S	S	.	.	H	α-helix	trans	-63.5	-22.9	172.3	72.7	0	0	0	0	113	K128 L132 F348 L349 M350	K128-T352 VanDerWaalsContact CE-O 3.24Å; K128-T352 WeakPolarHBondContact CE-O 3.43Å; K128-T352 PolarHBondContact NZ-O 3.09Å; L132-T352 HydrophobicContact CD2-CG2 3.98Å; F348-T352 HydrophobicContact CD1-CG2 4.23Å; F348-T352 HydrophobicContact CE1-CG2 3.94Å; F348-T352 HydrophobicContact CZ-CG2 4.44Å; F348-T352 WeakPolarHBondContact O-CG2 3.14Å; F348-T352 PolarHBondContact O-N 3Å; L349-T352 PolarHBondContact O-N 3.29Å; L349-T352 PolarHBondContact O-OG1 3.12Å; M350-T352 PolarHBondContact O-N 3.44Å
353	Q	90.2	Very high	76.2	Confident	117 Å²	117	66.6 Å²	66.6	55%	0.547	34%	0.344	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.1	-8	178.6	-56.8	-56.5	-44.9	0	0	112.7	V66 M350 A351 R355	V66-Q353 HydrophobicContact CG1-CB 3.68Å; V66-Q353 HydrophobicContact CG2-CB 4.15Å; M350-Q353 WeakPolarHBondContact O-CB 3.17Å; M350-Q353 PolarHBondContact O-N 3.13Å; A351-Q353 PolarHBondContact O-N 3.44Å; Q353-R355 PolarHBondContact O-N 3.35Å
354	F	85.4	Confident	73.5	Confident	0 Å²	0	67 Å²	67	0%	0	35%	0.352	C	S	.	.			trans	-64.9	134.2	172.9	-75.3	-0.9	0	0	0	111.1	V66 F70 K128 L131 A276 C279 M283 A351 F356	V66-F354 HydrophobicContact CG1-CD1 3.78Å; V66-F354 HydrophobicContact CG1-CE1 3.77Å; F70-F354 HydrophobicContact CB-CE1 4.08Å; F70-F354 HydrophobicContact CB-CZ 3.65Å; F70-F354 HydrophobicContact CD1-CE2 4.14Å; F70-F354 AromaticContact CD1-CZ 3.83Å; F70-F354 HydrophobicContact CD1-CZ 3.83Å; F70-F354 HydrophobicContact CD2-CE2 4.34Å; F70-F354 HydrophobicContact CD2-CZ 4.21Å; F70-F354 HydrophobicContact CG-CE1 4.43Å; F70-F354 HydrophobicContact CG-CE2 4.06Å; F70-F354 AromaticContact CG-CZ 3.6Å; F70-F354 HydrophobicContact CG-CZ 3.6Å; K128-F354 WeakPolarHBondContact CE-O 3.46Å; K128-F354 PolarHBondContact NZ-O 3.47Å; L131-F354 HydrophobicContact CD2-CD2 3.7Å; L131-F354 HydrophobicContact CD2-CE2 4.2Å; A276-F354 HydrophobicContact CB-CE2 4.03Å; C279-F354 HydrophobicContact CB-CD2 4.19Å; M283-F354 HydrophobicContact SD-CD1 4.5Å; A351-F354 WeakPolarHBondContact O-CB 3.44Å; A351-F354 PolarHBondContact O-N 3.5Å; A351-F354 VanDerWaalsContact O-N 3.15Å; F354-F356 HydrophobicContact CB-CD2 4.32Å; F354-F356 HydrophobicContact CB-CE2 3.93Å; F354-F356 HydrophobicContact CD2-CE2 4.45Å
355	R	77.6	Confident	70.7	Confident	153 Å²	153	73.2 Å²	73.2	58%	0.577	38%	0.38	S	S	*	.			trans	-105.9	109	174.4	-69.7	-177.1	175.6	167.7	-9.8	108.2	E63 Q353 E357	E63-R355 WeakPolarHBondContact OE1-CD 3.32Å; E63-R355 IonicContact OE1-CZ 3.69Å; E63-R355 IonicContact OE1-NE 2.94Å; E63-R355 IonicContact OE1-NH1 2.9Å; E63-R355 PolarHBondContact OE1-NH1 2.99Å; Q353-R355 PolarHBondContact O-N 3.35Å; R355-E357 PolarHBondContact O-N 3Å
356	F	73.3	Confident	68	Low	57 Å²	57	77 Å²	77	25%	0.25	39%	0.389	C	S	.	.			trans	-87.1	106	169.7	-72.9	-105.8	0	0	0	106	K128 L131 C279 F354 E358	K128-F356 VanDerWaalsContact CA-CE2 3.5Å; K128-F356 HydrophobicContact CB-CD2 3.45Å; K128-F356 VanDerWaalsContact CB-CD2 3.45Å; K128-F356 HydrophobicContact CB-CE2 3.76Å; K128-F356 HydrophobicContact CB-CG 4.12Å; K128-F356 HydrophobicContact CD-CD2 4.43Å; K128-F356 HydrophobicContact CG-CD2 4.04Å; K128-F356 HydrophobicContact CG-CE2 4.15Å; L131-F356 HydrophobicContact CB-CZ 4.43Å; L131-F356 HydrophobicContact CD2-CE2 4.07Å; L131-F356 HydrophobicContact CD2-CZ 3.93Å; C279-F356 HydrophobicContact CB-CE1 3.98Å; C279-F356 HydrophobicContact CB-CE2 4.3Å; C279-F356 HydrophobicContact CB-CZ 3.83Å; F354-F356 HydrophobicContact CB-CD2 4.32Å; F354-F356 HydrophobicContact CB-CE2 3.93Å; F354-F356 HydrophobicContact CD2-CE2 4.45Å; F356-E358 PolarHBondContact O-N 3.35Å
357	E	62	Low	65.5	Low	163 Å²	163	78.2 Å²	78.2	76%	0.762	40%	0.396	S	S	*	.			trans	-61.1	124.8	172	-73.8	-170.6	155.9	0	0	108.8	R355 Y359	R355-E357 PolarHBondContact O-N 3Å; E357-Y359 PolarHBondContact O-N 3.45Å
358	E	50.9	Low	62.8	Low	176 Å²	176	80.5 Å²	80.5	82%	0.822	41%	0.414	S	S	*	.			trans	-60.2	113.8	171.3	-76	-179.5	164.3	0	0	107.9	F356 G360	F356-E358 PolarHBondContact O-N 3.35Å; E358-G360 PolarHBondContact O-N 3.46Å
359	Y	45.6	Very low	60.3	Low	128 Å²	128	83.6 Å²	83.6	50%	0.502	43%	0.43	S	S	.	.			trans	-65	88.4	176.2	-133.6	-95.5	0	0	0	108.9	E357 A364	E357-Y359 PolarHBondContact O-N 3.45Å; Y359-A364 HydrophobicContact CE1-CB 3.69Å; Y359-A364 WeakPolarHBondContact OH-CA 3.31Å; Y359-A364 VanDerWaalsContact OH-CB 3.28Å; Y359-A364 WeakPolarHBondContact OH-CB 3.42Å
360	G	39.6	Very low	57.8	Low	45 Å²	45	84.9 Å²	84.9	46%	0.464	43%	0.427	S	S	.	.			trans	-66.1	133.4	154.7	0	0	0	0	0	107.2	E358 G362 S363	E358-G360 PolarHBondContact O-N 3.46Å; G360-G362 PolarHBondContact O-N 3.27Å; G360-S363 PolarHBondContact O-N 3.34Å
361	D	39	Very low	55.5	Low	131 Å²	131	87.4 Å²	87.4	70%	0.701	44%	0.441	S	S	*	.	T	Hydrogen-bonded Turn	trans	-46.2	-11.8	179	-166.2	32.2	0	0	0	114.9
362	G	36.7	Very low	53.2	Low	33 Å²	33	91.5 Å²	91.5	34%	0.34	46%	0.461	S	S	.	.	H	α-helix	trans	-86.3	-13.9	173.5	0	0	0	0	0	116.8	G360 K366	G360-G362 PolarHBondContact O-N 3.27Å; G362-K366 WeakPolarHBondContact O-CA 3.12Å; G362-K366 WeakPolarHBondContact O-CB 3.3Å; G362-K366 WeakPolarHBondContact O-CG 3.46Å; G362-K366 PolarHBondContact O-N 3.29Å
363	S	40.6	Very low	51.1	Low	33 Å²	33	93.6 Å²	93.6	23%	0.231	47%	0.471	C	S	.	.	H	α-helix	trans	-77.4	-45.1	-172.5	-161.5	0	0	0	0	113.3	G360 K365 K366 V367	G360-S363 PolarHBondContact O-N 3.34Å; S363-K365 VanDerWaalsContact C-N 3.31Å; S363-K365 PolarHBondContact O-N 3.32Å; S363-K366 CarbonylContact O-C 3.55Å; S363-K366 PolarHBondContact O-N 3.46Å; S363-V367 WeakPolarHBondContact O-CG2 3.32Å; S363-V367 PolarHBondContact O-N 2.89Å
364	A	42.7	Very low	49.2	Very low	44 Å²	44	92.1 Å²	92.1	36%	0.364	47%	0.473	S	S	.	.	H	α-helix	trans	-55.6	-48.3	169.3	0	0	0	0	0	111.3	Y359 K366 V367 A368	Y359-A364 HydrophobicContact CE1-CB 3.69Å; Y359-A364 WeakPolarHBondContact OH-CA 3.31Å; Y359-A364 VanDerWaalsContact OH-CB 3.28Å; Y359-A364 WeakPolarHBondContact OH-CB 3.42Å; A364-K366 PolarHBondContact O-N 3.37Å; A364-V367 PolarHBondContact O-N 2.89Å; A364-A368 VanDerWaalsContact O-CB 3.3Å; A364-A368 WeakPolarHBondContact O-CB 3.34Å; A364-A368 PolarHBondContact O-N 3.22Å
365	K	37.8	Very low	47.5	Very low	131 Å²	131	95.9 Å²	95.9	57%	0.57	49%	0.49	S	S	*	.	H	α-helix	trans	-60.2	-43.8	176.2	-77.1	178.1	177.3	167.3	0	111.4	S363 V367 A368 Q369	S363-K365 VanDerWaalsContact C-N 3.31Å; S363-K365 PolarHBondContact O-N 3.32Å; K365-V367 PolarHBondContact O-N 3.27Å; K365-A368 PolarHBondContact O-N 3.04Å; K365-Q369 WeakPolarHBondContact O-CA 3.33Å; K365-Q369 WeakPolarHBondContact O-CB 3.48Å; K365-Q369 PolarHBondContact O-N 2.92Å
366	K	41.8	Very low	46.1	Very low	129 Å²	129	90.6 Å²	90.6	56%	0.561	47%	0.473	S	S	*	.	H	α-helix	trans	-68.7	-30.8	177.8	-81.2	174.4	179.6	-176	0	113.2	G362 S363 A364 R370	G362-K366 WeakPolarHBondContact O-CA 3.12Å; G362-K366 WeakPolarHBondContact O-CB 3.3Å; G362-K366 WeakPolarHBondContact O-CG 3.46Å; G362-K366 PolarHBondContact O-N 3.29Å; S363-K366 CarbonylContact O-C 3.55Å; S363-K366 PolarHBondContact O-N 3.46Å; A364-K366 PolarHBondContact O-N 3.37Å; K366-R370 WeakPolarHBondContact O-CB 3.5Å; K366-R370 WeakPolarHBondContact O-CG 3.39Å; K366-R370 PolarHBondContact O-N 3.36Å; K366-R370 PolarHBondContact O-NE 2.82Å; K366-R370 VanDerWaalsContact O-NE 3.09Å
367	V	43.8	Very low	45	Very low	67 Å²	67	91.3 Å²	91.3	41%	0.406	50%	0.497	S	S	.	.	H	α-helix	trans	-76.7	-46.4	175.3	172.3	0	0	0	0	109.6	S363 A364 K365 Q369 R370 I371	S363-V367 WeakPolarHBondContact O-CG2 3.32Å; S363-V367 PolarHBondContact O-N 2.89Å; A364-V367 PolarHBondContact O-N 2.89Å; K365-V367 PolarHBondContact O-N 3.27Å; V367-Q369 VanDerWaalsContact C-N 3.34Å; V367-Q369 PolarHBondContact O-N 3.37Å; V367-R370 PolarHBondContact O-N 3.3Å; V367-I371 HydrophobicContact CG1-CD1 3.82Å; V367-I371 HydrophobicContact CG1-CG1 4.49Å; V367-I371 WeakPolarHBondContact O-CB 3.38Å; V367-I371 WeakPolarHBondContact O-CD1 3.28Å; V367-I371 WeakPolarHBondContact O-CG1 3.38Å; V367-I371 PolarHBondContact O-N 3.46Å
368	A	41.1	Very low	44.7	Very low	47 Å²	47	90.5 Å²	90.5	39%	0.388	50%	0.498	S	S	.	.	H	α-helix	trans	-59.8	-43.5	173.7	0	0	0	0	0	112.1	A364 K365 I371 M372	A364-A368 VanDerWaalsContact O-CB 3.3Å; A364-A368 WeakPolarHBondContact O-CB 3.34Å; A364-A368 PolarHBondContact O-N 3.22Å; K365-A368 PolarHBondContact O-N 3.04Å; A368-I371 PolarHBondContact O-N 3.47Å; A368-M372 WeakPolarHBondContact O-CG 3.3Å; A368-M372 PolarHBondContact O-N 3.23Å
369	Q	43.1	Very low	44.8	Very low	117 Å²	117	85.8 Å²	85.8	55%	0.547	48%	0.478	S	S	.	.	H	α-helix	trans	-69.6	-38.3	177.5	-169.4	162.6	5.6	0	0	111.8	K365 V367 M372 D373	K365-Q369 WeakPolarHBondContact O-CA 3.33Å; K365-Q369 WeakPolarHBondContact O-CB 3.48Å; K365-Q369 PolarHBondContact O-N 2.92Å; V367-Q369 VanDerWaalsContact C-N 3.34Å; V367-Q369 PolarHBondContact O-N 3.37Å; Q369-M372 PolarHBondContact O-N 2.96Å; Q369-D373 WeakPolarHBondContact O-CB 3.41Å; Q369-D373 PolarHBondContact O-N 2.94Å
370	R	44.2	Very low	45.3	Very low	129 Å²	129	84.4 Å²	84.4	49%	0.487	48%	0.479	S	S	.	.	H	α-helix	trans	-66.6	-35.9	171.9	-83.3	-177.1	-88	177.9	-6.7	112.9	K366 V367 D373 S374	K366-R370 WeakPolarHBondContact O-CB 3.5Å; K366-R370 WeakPolarHBondContact O-CG 3.39Å; K366-R370 PolarHBondContact O-N 3.36Å; K366-R370 PolarHBondContact O-NE 2.82Å; K366-R370 VanDerWaalsContact O-NE 3.09Å; V367-R370 PolarHBondContact O-N 3.3Å; R370-D373 PolarHBondContact O-N 3.27Å; R370-S374 VanDerWaalsContact O-CB 3.31Å; R370-S374 WeakPolarHBondContact O-CB 3.5Å; R370-S374 PolarHBondContact O-N 2.82Å
371	I	45	Very low	46.2	Very low	95 Å²	95	86.9 Å²	86.9	49%	0.487	49%	0.487	S	S	.	.	H	α-helix	trans	-64.3	-44.1	172.8	-69.7	164.4	0	0	0	109.5	V367 A368 S374 Q375	V367-I371 HydrophobicContact CG1-CD1 3.82Å; V367-I371 HydrophobicContact CG1-CG1 4.49Å; V367-I371 WeakPolarHBondContact O-CB 3.38Å; V367-I371 WeakPolarHBondContact O-CD1 3.28Å; V367-I371 WeakPolarHBondContact O-CG1 3.38Å; V367-I371 PolarHBondContact O-N 3.46Å; A368-I371 PolarHBondContact O-N 3.47Å; I371-S374 PolarHBondContact O-N 2.83Å; I371-S374 PolarHBondContact O-OG 3.14Å; I371-Q375 WeakPolarHBondContact O-CG 3.33Å; I371-Q375 PolarHBondContact O-N 3.28Å
372	M	43.9	Very low	47.3	Very low	86 Å²	86	86.7 Å²	86.7	42%	0.424	49%	0.486	S	S	.	.	H	α-helix	trans	-61.9	-47.5	172.8	-72.4	-172.1	-150.8	0	0	112.2	A368 Q369 S374 Q375 I376 A391	A368-M372 WeakPolarHBondContact O-CG 3.3Å; A368-M372 PolarHBondContact O-N 3.23Å; Q369-M372 PolarHBondContact O-N 2.96Å; M372-S374 PolarHBondContact O-N 2.93Å; M372-Q375 WeakPolarHBondContact O-CA 3.1Å; M372-Q375 WeakPolarHBondContact O-CB 3.46Å; M372-Q375 PolarHBondContact O-N 2.79Å; M372-I376 HydrophobicContact CB-CD1 4.49Å; M372-I376 VanDerWaalsContact O-CG1 3.28Å; M372-I376 WeakPolarHBondContact O-CG1 3.47Å; M372-I376 PolarHBondContact O-N 2.87Å; M372-A391 HydrophobicContact CE-CB 4.28Å; M372-A391 HydrophobicContact SD-CB 4.3Å
373	D	48.7	Very low	48.3	Very low	85 Å²	85	88.5 Å²	88.5	46%	0.455	49%	0.49	S	S	.	.	H	α-helix	trans	-62.3	-32	179	-69.9	-25.6	0	0	0	112.1	Q369 R370 Q375	Q369-D373 WeakPolarHBondContact O-CB 3.41Å; Q369-D373 PolarHBondContact O-N 2.94Å; R370-D373 PolarHBondContact O-N 3.27Å; D373-Q375 PolarHBondContact O-N 2.9Å
374	S	51.3	Low	49	Very low	85 Å²	85	87.2 Å²	87.2	59%	0.594	48%	0.481	S	S	*	.	H	α-helix	trans	-68.2	-22.6	174.2	80.7	0	0	0	0	113	R370 I371 M372	R370-S374 VanDerWaalsContact O-CB 3.31Å; R370-S374 WeakPolarHBondContact O-CB 3.5Å; R370-S374 PolarHBondContact O-N 2.82Å; I371-S374 PolarHBondContact O-N 2.83Å; I371-S374 PolarHBondContact O-OG 3.14Å; M372-S374 PolarHBondContact O-N 2.93Å
375	Q	48.6	Very low	49.6	Very low	79 Å²	79	89.4 Å²	89.4	37%	0.369	49%	0.487	S	S	.	.	H	α-helix	trans	-95.5	-27.8	179.8	-57.8	-117.5	-37.2	0	0	112.2	I371 M372 D373 G377 N378 L379	I371-Q375 WeakPolarHBondContact O-CG 3.33Å; I371-Q375 PolarHBondContact O-N 3.28Å; M372-Q375 WeakPolarHBondContact O-CA 3.1Å; M372-Q375 WeakPolarHBondContact O-CB 3.46Å; M372-Q375 PolarHBondContact O-N 2.79Å; D373-Q375 PolarHBondContact O-N 2.9Å; Q375-G377 PolarHBondContact O-N 2.96Å; Q375-N378 PolarHBondContact O-N 2.93Å; Q375-L379 WeakPolarHBondContact O-CD1 3.48Å
376	I	49.3	Very low	50.6	Low	42 Å²	42	88.5 Å²	88.5	22%	0.215	49%	0.485	C	S	.	.	H	α-helix	trans	-64.4	-23.7	-177.7	-74.4	163.6	0	0	0	113.1	M372 N378 L379 A384	M372-I376 HydrophobicContact CB-CD1 4.49Å; M372-I376 VanDerWaalsContact O-CG1 3.28Å; M372-I376 WeakPolarHBondContact O-CG1 3.47Å; M372-I376 PolarHBondContact O-N 2.87Å; I376-N378 PolarHBondContact O-N 3.28Å; I376-L379 PolarHBondContact O-N 3.37Å; I376-L379 VanDerWaalsContact O-N 3.16Å; I376-A384 HydrophobicContact CG1-CB 4.33Å; I376-A384 HydrophobicContact CG2-CB 3.92Å
377	G	49.9	Very low	50.8	Low	72 Å²	72	84.3 Å²	84.3	74%	0.742	48%	0.475	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62	-14.4	175.4	0	0	0	0	0	114.9	Q375	Q375-G377 PolarHBondContact O-N 2.96Å
378	N	54.6	Low	51	Low	146 Å²	146	87.9 Å²	87.9	78%	0.781	48%	0.481	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.2	8.3	178.5	-69.2	-36.8	0	0	0	113.5	Q375 I376	Q375-N378 PolarHBondContact O-N 2.93Å; I376-N378 PolarHBondContact O-N 3.28Å
379	L	53.4	Low	51.6	Low	77 Å²	77	90.6 Å²	90.6	40%	0.403	49%	0.492	S	S	.	.	S	Bend	trans	-108.4	146.7	179.8	-89.4	86	0	0	0	111.9	Q375 I376 V383	Q375-L379 WeakPolarHBondContact O-CD1 3.48Å; I376-L379 PolarHBondContact O-N 3.37Å; I376-L379 VanDerWaalsContact O-N 3.16Å; L379-V383 HydrophobicContact CD2-CB 4.24Å; L379-V383 HydrophobicContact CD2-CG1 3.68Å
380	D	57.3	Low	51.8	Low	99 Å²	99	91 Å²	91	53%	0.529	49%	0.494	S	S	.	.			trans	-56.4	134.2	170.6	-168	-58.1	0	0	0	110.3	D382 V383 A384	D380-D382 PolarHBondContact O-N 3.49Å; D380-D382 VanDerWaalsContact O-N 3.14Å; D380-D382 PolarHBondContact OD1-N 3.49Å; D380-V383 HydrophobicContact CB-CG2 4.06Å; D380-V383 PolarHBondContact O-N 2.94Å; D380-A384 PolarHBondContact O-N 2.9Å
381	P	56.9	Low	51.7	Low	97 Å²	97	86.6 Å²	86.6	63%	0.63	49%	0.486	S	S	*	.	H	α-helix	trans	-54.2	-31.3	-176.3	16.9	-30	0	0	0	114.5	A384 D385	P381-A384 PolarHBondContact O-N 3.02Å; P381-D385 PolarHBondContact O-N 2.84Å
382	D	63.5	Low	51.4	Low	128 Å²	128	87.3 Å²	87.3	68%	0.684	50%	0.497	S	S	*	.	H	α-helix	trans	-71.1	-35.9	177.2	-75	-19.4	0	0	0	111.9	D380 D385 Q386	D380-D382 PolarHBondContact O-N 3.49Å; D380-D382 VanDerWaalsContact O-N 3.14Å; D380-D382 PolarHBondContact OD1-N 3.49Å; D382-D385 PolarHBondContact O-N 2.96Å; D382-Q386 WeakPolarHBondContact O-CB 3.44Å; D382-Q386 PolarHBondContact O-N 3.19Å
383	V	57.8	Low	50.9	Low	71 Å²	71	91.1 Å²	91.1	43%	0.43	51%	0.514	S	S	.	.	H	α-helix	trans	-73.3	-34.2	176.8	-172.6	0	0	0	0	110.6	L379 D380 Q386 A387	L379-V383 HydrophobicContact CD2-CB 4.24Å; L379-V383 HydrophobicContact CD2-CG1 3.68Å; D380-V383 HydrophobicContact CB-CG2 4.06Å; D380-V383 PolarHBondContact O-N 2.94Å; V383-Q386 PolarHBondContact O-N 3.25Å; V383-A387 VanDerWaalsContact O-CB 3.27Å; V383-A387 WeakPolarHBondContact O-CB 3.26Å; V383-A387 PolarHBondContact O-N 3.31Å
384	A	53.8	Low	50.1	Low	5 Å²	5	90.9 Å²	90.9	4%	0.041	52%	0.523	C	S	.	.	H	α-helix	trans	-65.7	-39.5	173.9	0	0	0	0	0	112.1	I376 D380 P381 R388	I376-A384 HydrophobicContact CG1-CB 4.33Å; I376-A384 HydrophobicContact CG2-CB 3.92Å; D380-A384 PolarHBondContact O-N 2.9Å; P381-A384 PolarHBondContact O-N 3.02Å; A384-R388 WeakPolarHBondContact O-CG 3.25Å; A384-R388 PolarHBondContact O-N 3.32Å
385	D	57	Low	49	Very low	91 Å²	91	97.1 Å²	97.1	49%	0.487	53%	0.534	S	S	.	.	H	α-helix	trans	-72.8	-36.1	175.6	-108.4	14.4	0	0	0	112.2	P381 D382 R388 T389	P381-D385 PolarHBondContact O-N 2.84Å; D382-D385 PolarHBondContact O-N 2.96Å; D385-R388 WeakPolarHBondContact O-CB 3.12Å; D385-R388 PolarHBondContact O-N 3.23Å; D385-R388 IonicContact OD1-CZ 3.87Å; D385-R388 IonicContact OD1-NH1 2.87Å; D385-R388 PolarHBondContact OD1-NH1 3.25Å; D385-T389 PolarHBondContact O-N 3.47Å; D385-T389 PolarHBondContact O-OG1 3.07Å
386	Q	57.2	Low	48	Very low	111 Å²	111	102.5 Å²	102.5	52%	0.519	56%	0.559	S	S	.	*	H	α-helix	trans	-64.2	-43.1	173.2	-160.9	171.9	-6.8	0	0	111.5	D382 V383 R388 T389 E390	D382-Q386 WeakPolarHBondContact O-CB 3.44Å; D382-Q386 PolarHBondContact O-N 3.19Å; V383-Q386 PolarHBondContact O-N 3.25Å; Q386-R388 VanDerWaalsContact C-N 3.31Å; Q386-R388 PolarHBondContact O-N 3.45Å; Q386-T389 WeakPolarHBondContact CA-OG1 3.41Å; Q386-T389 PolarHBondContact O-N 3.23Å; Q386-T389 VanDerWaalsContact O-N 3.16Å; Q386-T389 PolarHBondContact O-OG1 3.12Å; Q386-E390 WeakPolarHBondContact O-CG 3.47Å; Q386-E390 PolarHBondContact O-N 3.4Å
387	A	46.2	Very low	47.4	Very low	42 Å²	42	105.6 Å²	105.6	35%	0.347	58%	0.579	S	S	.	*	H	α-helix	trans	-61.2	-36.5	172.1	0	0	0	0	0	112.3	V383 A391	V383-A387 VanDerWaalsContact O-CB 3.27Å; V383-A387 WeakPolarHBondContact O-CB 3.26Å; V383-A387 PolarHBondContact O-N 3.31Å; A387-A391 WeakPolarHBondContact O-CB 3.48Å; A387-A391 PolarHBondContact O-N 3.21Å
388	R	48.2	Very low	46.5	Very low	141 Å²	141	105.7 Å²	105.7	53%	0.532	57%	0.569	S	S	.	*	H	α-helix	trans	-67.7	-34.3	173.4	-78.5	174.4	-174.8	151.9	1.3	113.4	A384 D385 Q386 P392	A384-R388 WeakPolarHBondContact O-CG 3.25Å; A384-R388 PolarHBondContact O-N 3.32Å; D385-R388 WeakPolarHBondContact O-CB 3.12Å; D385-R388 PolarHBondContact O-N 3.23Å; D385-R388 IonicContact OD1-CZ 3.87Å; D385-R388 IonicContact OD1-NH1 2.87Å; D385-R388 PolarHBondContact OD1-NH1 3.25Å; Q386-R388 VanDerWaalsContact C-N 3.31Å; Q386-R388 PolarHBondContact O-N 3.45Å; R388-P392 WeakPolarHBondContact O-CD 3.5Å
389	T	53.4	Low	46	Very low	104 Å²	104	107.5 Å²	107.5	64%	0.638	57%	0.572	S	S	*	*	H	α-helix	trans	-77.1	-27.5	177.8	50	0	0	0	0	113.3	D385 Q386 P392	D385-T389 PolarHBondContact O-N 3.47Å; D385-T389 PolarHBondContact O-OG1 3.07Å; Q386-T389 WeakPolarHBondContact CA-OG1 3.41Å; Q386-T389 PolarHBondContact O-N 3.23Å; Q386-T389 VanDerWaalsContact O-N 3.16Å; Q386-T389 PolarHBondContact O-OG1 3.12Å; T389-P392 WeakPolarHBondContact O-CD 3.24Å
390	E	47.7	Very low	45.7	Very low	125 Å²	125	105.8 Å²	105.8	58%	0.584	57%	0.574	S	S	*	*	H	α-helix	trans	-88.9	-22.9	177.3	-67.2	179.4	-175.9	0	0	112.8	Q386 E393	Q386-E390 WeakPolarHBondContact O-CG 3.47Å; Q386-E390 PolarHBondContact O-N 3.4Å; E390-E393 PolarHBondContact O-N 2.88Å
391	A	43.2	Very low	45.5	Very low	37 Å²	37	104.7 Å²	104.7	31%	0.306	57%	0.572	S	S	.	*	G	3₁₀ helix	trans	-61.1	-30.8	-179.9	0	0	0	0	0	117.2	M372 A387 E393 A394	M372-A391 HydrophobicContact CE-CB 4.28Å; M372-A391 HydrophobicContact SD-CB 4.3Å; A387-A391 WeakPolarHBondContact O-CB 3.48Å; A387-A391 PolarHBondContact O-N 3.21Å; A391-E393 PolarHBondContact O-N 3.38Å; A391-A394 PolarHBondContact O-N 2.95Å
392	P	38.6	Very low	45.8	Very low	111 Å²	111	105.3 Å²	105.3	72%	0.721	57%	0.565	S	S	*	*	G	3₁₀ helix	trans	-72.5	-19.1	178.5	-12.7	28.2	0	0	0	112.8	R388 T389	R388-P392 WeakPolarHBondContact O-CD 3.5Å; T389-P392 WeakPolarHBondContact O-CD 3.24Å
393	E	31.9	Very low	45.9	Very low	166 Å²	166	103.3 Å²	103.3	78%	0.776	55%	0.548	S	S	*	.	G	3₁₀ helix	trans	-103.7	10.7	178.1	-70.8	-166.7	164	0	0	113.4	E390 A391 R395	E390-E393 PolarHBondContact O-N 2.88Å; A391-E393 PolarHBondContact O-N 3.38Å; E393-R395 WeakPolarHBondContact O-CG 3.33Å; E393-R395 PolarHBondContact O-N 3.45Å
394	A	31.4	Very low	46.6	Very low	80 Å²	80	108.9 Å²	108.9	66%	0.661	57%	0.566	S	S	*	*	S	Bend	trans	-67.6	75	163.7	0	0	0	0	0	109.2	A391	A391-A394 PolarHBondContact O-N 2.95Å
395	R	29.8	Very low	47.4	Very low	215 Å²	215	110 Å²	110	81%	0.811	58%	0.576	S	S	*	*			trans	-8.5	130.6	176.4	-67.1	169.6	177.1	163.3	-0.7	113.8	E393 V397	E393-R395 WeakPolarHBondContact O-CG 3.33Å; E393-R395 PolarHBondContact O-N 3.45Å; R395-V397 VanDerWaalsContact C-N 3.3Å; R395-V397 PolarHBondContact O-N 3.34Å
396	E	27.7	Very low	48.1	Very low	192 Å²	192	105.8 Å²	105.8	90%	0.897	55%	0.553	S	S	*	*			trans	-29.6	97	150.3	-68.2	-178.1	154	0	0	109.6	S398	E396-S398 VanDerWaalsContact C-N 3.26Å; E396-S398 PolarHBondContact O-N 2.94Å
397	V	35.7	Very low	49	Very low	107 Å²	107	104.8 Å²	104.8	65%	0.648	55%	0.551	S	S	*	*			trans	-66	102	172.5	175.7	0	0	0	0	102.8	R395 H399	R395-V397 VanDerWaalsContact C-N 3.3Å; R395-V397 PolarHBondContact O-N 3.34Å; V397-H399 VanDerWaalsContact C-N 3.28Å; V397-H399 PolarHBondContact O-CD2 3.41Å; V397-H399 PolarHBondContact O-N 3.49Å
398	S	31.2	Very low	50.6	Low	75 Å²	75	110.7 Å²	110.7	52%	0.524	57%	0.568	S	S	.	*			trans	-48.2	97.9	174.5	137.2	0	0	0	0	107.7	E396 G400	E396-S398 VanDerWaalsContact C-N 3.26Å; E396-S398 PolarHBondContact O-N 2.94Å; S398-G400 PolarHBondContact O-N 2.8Å
399	H	43.2	Very low	51.6	Low	183 Å²	183	105.8 Å²	105.8	85%	0.847	55%	0.554	S	S	*	*			trans	-72.9	16.5	-169.8	-90.7	-81.8	0	0	0	113.4	V397	V397-H399 VanDerWaalsContact C-N 3.28Å; V397-H399 PolarHBondContact O-CD2 3.41Å; V397-H399 PolarHBondContact O-N 3.49Å
400	G	48.4	Very low	52.8	Low	42 Å²	42	101.3 Å²	101.3	43%	0.433	53%	0.526	S	S	.	.	S	Bend	trans	-86.5	130.3	171.5	0	0	0	0	0	110.6	S398 K402	S398-G400 PolarHBondContact O-N 2.8Å; G400-K402 PolarHBondContact O-N 3.35Å
401	P	52.5	Low	54.2	Low	76 Å²	76	98.7 Å²	98.7	49%	0.494	53%	0.526	S	S	.	.			trans	-63.6	108	172.9	27.4	-33.6	0	0	0	109	W403	P401-W403 HydrophobicContact CB-CD2 4.43Å; P401-W403 HydrophobicContact CB-CG 4.34Å; P401-W403 HydrophobicContact CB-CZ2 4.39Å; P401-W403 VanDerWaalsContact CB-NE1 3.3Å; P401-W403 VanDerWaalsContact CG-NE1 3.31Å; P401-W403 VanDerWaalsContact O-CD1 3.28Å; P401-W403 PolarHBondContact O-N 3.34Å
402	K	62.5	Low	55.9	Low	109 Å²	109	104.2 Å²	104.2	47%	0.474	54%	0.54	S	S	.	.			trans	-76.3	60.4	175.7	-65.4	-175.3	-177.1	175.5	0	110.5	G400 F404 A405 V406 Y534	G400-K402 PolarHBondContact O-N 3.35Å; K402-F404 PolarHBondContact O-N 3.22Å; K402-F404 VanDerWaalsContact O-N 3.1Å; K402-A405 HydrophobicContact CB-CB 4.16Å; K402-A405 WeakPolarHBondContact O-CB 3.49Å; K402-A405 PolarHBondContact O-N 3.47Å; K402-V406 PolarHBondContact O-N 3.17Å; K402-Y534 HydrophobicContact CB-CE1 4.11Å; K402-Y534 HydrophobicContact CD-CE1 4.27Å
403	W	67.6	Low	57.8	Low	87 Å²	87	102.5 Å²	102.5	33%	0.33	53%	0.528	S	S	.	.	H	α-helix	trans	-49	-38.7	-179.2	-69.3	107.5	0	0	0	112.7	P401 A405 V406 I407 L541	P401-W403 HydrophobicContact CB-CD2 4.43Å; P401-W403 HydrophobicContact CB-CG 4.34Å; P401-W403 HydrophobicContact CB-CZ2 4.39Å; P401-W403 VanDerWaalsContact CB-NE1 3.3Å; P401-W403 VanDerWaalsContact CG-NE1 3.31Å; P401-W403 VanDerWaalsContact O-CD1 3.28Å; P401-W403 PolarHBondContact O-N 3.34Å; W403-A405 PolarHBondContact O-N 2.88Å; W403-V406 WeakPolarHBondContact O-CB 3.36Å; W403-V406 PolarHBondContact O-N 3.32Å; W403-I407 VanDerWaalsContact O-CG1 3.25Å; W403-I407 WeakPolarHBondContact O-CG1 3.35Å; W403-I407 PolarHBondContact O-N 3.05Å; W403-L541 HydrophobicContact CZ3-CB 4.33Å
404	F	72.3	Confident	60	Low	187 Å²	187	96.3 Å²	96.3	82%	0.82	50%	0.499	S	S	*	.	H	α-helix	trans	-62.2	-39	177.9	-72.7	-74.8	0	0	0	113.8	K402 K408	K402-F404 PolarHBondContact O-N 3.22Å; K402-F404 VanDerWaalsContact O-N 3.1Å; F404-K408 WeakPolarHBondContact O-CB 3.41Å; F404-K408 PolarHBondContact O-N 3.35Å
405	A	70.4	Confident	62.5	Low	30 Å²	30	94.4 Å²	94.4	25%	0.248	48%	0.476	C	S	.	.	H	α-helix	trans	-67	-42.5	177.8	0	0	0	0	0	110.7	K402 W403 K408 T409 Y534	K402-A405 HydrophobicContact CB-CB 4.16Å; K402-A405 WeakPolarHBondContact O-CB 3.49Å; K402-A405 PolarHBondContact O-N 3.47Å; W403-A405 PolarHBondContact O-N 2.88Å; A405-K408 PolarHBondContact O-N 2.75Å; A405-T409 PolarHBondContact O-N 3.23Å; A405-T409 PolarHBondContact O-OG1 3.45Å; A405-T409 VanDerWaalsContact O-OG1 3.09Å; A405-Y534 HydrophobicContact CB-CE1 4.37Å; A405-Y534 HydrophobicContact CB-CE2 4.13Å
406	V	70.7	Confident	65.2	Low	1 Å²	1	86.2 Å²	86.2	1%	0.006	45%	0.453	C	S	.	.	H	α-helix	trans	-59.8	-54.7	175.7	-179.1	0	0	0	0	110.3	K402 W403 K408 T409 F410 Y534 A538 L541	K402-V406 PolarHBondContact O-N 3.17Å; W403-V406 WeakPolarHBondContact O-CB 3.36Å; W403-V406 PolarHBondContact O-N 3.32Å; V406-K408 PolarHBondContact O-N 3.05Å; V406-T409 WeakPolarHBondContact O-CB 3.41Å; V406-T409 PolarHBondContact O-N 3.09Å; V406-F410 HydrophobicContact CG1-CD2 3.67Å; V406-F410 HydrophobicContact CG1-CE2 3.8Å; V406-F410 WeakPolarHBondContact O-CD2 3.07Å; V406-F410 PolarHBondContact O-N 3.01Å; V406-Y534 HydrophobicContact CG2-CD1 4.44Å; V406-Y534 HydrophobicContact CG2-CG 4.26Å; V406-A538 HydrophobicContact CG1-CB 4.29Å; V406-L541 HydrophobicContact CG1-CD2 3.93Å
407	I	77.5	Confident	68.1	Low	91 Å²	91	77.8 Å²	77.8	47%	0.467	42%	0.417	S	S	.	.	H	α-helix	trans	-56.6	-40.7	-179.3	-67.9	164.9	0	0	0	110.9	W403 F410 A411	W403-I407 VanDerWaalsContact O-CG1 3.25Å; W403-I407 WeakPolarHBondContact O-CG1 3.35Å; W403-I407 PolarHBondContact O-N 3.05Å; I407-F410 PolarHBondContact O-N 2.96Å; I407-A411 PolarHBondContact O-N 3.45Å
408	K	78.4	Confident	70.6	Confident	165 Å²	165	72.8 Å²	72.8	72%	0.717	39%	0.387	S	S	*	.	H	α-helix	trans	-64.4	-41.5	176.7	-170.9	177.3	-179	179.5	0	112.4	F404 A405 V406 F410 A411	F404-K408 WeakPolarHBondContact O-CB 3.41Å; F404-K408 PolarHBondContact O-N 3.35Å; A405-K408 PolarHBondContact O-N 2.75Å; V406-K408 PolarHBondContact O-N 3.05Å; K408-F410 VanDerWaalsContact C-N 3.32Å; K408-A411 WeakPolarHBondContact O-CB 3.41Å; K408-A411 PolarHBondContact O-N 3.41Å
409	T	70.7	Confident	73.5	Confident	38 Å²	38	70 Å²	70	23%	0.233	37%	0.366	C	S	.	.	H	α-helix	trans	-63.9	-37.8	175	-58.1	0	0	0	0	111.7	A405 V406 A411 Y412	A405-T409 PolarHBondContact O-N 3.23Å; A405-T409 PolarHBondContact O-OG1 3.45Å; A405-T409 VanDerWaalsContact O-OG1 3.09Å; V406-T409 WeakPolarHBondContact O-CB 3.41Å; V406-T409 PolarHBondContact O-N 3.09Å; T409-A411 VanDerWaalsContact C-N 3.29Å; T409-A411 PolarHBondContact O-N 3.36Å; T409-Y412 WeakPolarHBondContact O-CD2 3.49Å
410	F	77.7	Confident	75.9	Confident	11 Å²	11	66 Å²	66	5%	0.048	35%	0.346	C	S	.	.	H	α-helix	trans	-84.6	-1.1	-179.5	-73.5	-78.2	0	0	0	114.1	V406 I407 K408 Y412 Y415 A416 L419 I526 A529 A530 A538 L541	V406-F410 HydrophobicContact CG1-CD2 3.67Å; V406-F410 HydrophobicContact CG1-CE2 3.8Å; V406-F410 WeakPolarHBondContact O-CD2 3.07Å; V406-F410 PolarHBondContact O-N 3.01Å; I407-F410 PolarHBondContact O-N 2.96Å; K408-F410 VanDerWaalsContact C-N 3.32Å; F410-Y412 VanDerWaalsContact C-N 3.29Å; F410-Y412 PolarHBondContact O-N 3.48Å; F410-Y415 HydrophobicContact CD1-CG 4.16Å; F410-Y415 HydrophobicContact CE1-CD1 4.43Å; F410-Y415 HydrophobicContact CE1-CG 4.42Å; F410-A416 PolarHBondContact O-N 3.04Å; F410-L419 HydrophobicContact CB-CD1 3.63Å; F410-L419 HydrophobicContact CD1-CD1 3.96Å; F410-L419 HydrophobicContact CD1-CG 4.4Å; F410-L419 HydrophobicContact CG-CD1 3.99Å; F410-I526 HydrophobicContact CD1-CD1 4.45Å; F410-I526 HydrophobicContact CD1-CG1 4.35Å; F410-I526 HydrophobicContact CE1-CD1 3.94Å; F410-I526 HydrophobicContact CE1-CG1 3.41Å; F410-I526 VanDerWaalsContact CE1-CG1 3.41Å; F410-I526 HydrophobicContact CE2-CD1 4.44Å; F410-I526 HydrophobicContact CE2-CG1 4.24Å; F410-I526 HydrophobicContact CZ-CD1 3.94Å; F410-I526 HydrophobicContact CZ-CG1 3.35Å; F410-A529 HydrophobicContact CE1-CB 4.33Å; F410-A530 HydrophobicContact CE2-CB 4.45Å; F410-A530 HydrophobicContact CZ-CB 4.21Å; F410-A538 HydrophobicContact CE2-CB 3.75Å; F410-A538 HydrophobicContact CZ-CB 4Å; F410-L541 HydrophobicContact CD2-CD2 4.2Å; F410-L541 HydrophobicContact CG-CD2 4.45Å
411	A	77.1	Confident	78	Confident	70 Å²	70	64.1 Å²	64.1	58%	0.579	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77.1	-10.6	174.9	0	0	0	0	0	113.6	I407 K408 T409	I407-A411 PolarHBondContact O-N 3.45Å; K408-A411 WeakPolarHBondContact O-CB 3.41Å; K408-A411 PolarHBondContact O-N 3.41Å; T409-A411 VanDerWaalsContact C-N 3.29Å; T409-A411 PolarHBondContact O-N 3.36Å
412	Y	79	Confident	79.9	Confident	152 Å²	152	60.5 Å²	60.5	60%	0.596	30%	0.303	S	S	*	.	S	Bend	trans	-62.4	139.9	171.9	-71.3	-73.4	0	0	0	110.4	T409 F410 H414 Y415 A416	T409-Y412 WeakPolarHBondContact O-CD2 3.49Å; F410-Y412 VanDerWaalsContact C-N 3.29Å; F410-Y412 PolarHBondContact O-N 3.48Å; Y412-H414 PolarHBondContact O-N 3.24Å; Y412-Y415 HydrophobicContact CD2-CD2 4.37Å; Y412-Y415 PolarHBondContact O-N 3.46Å; Y412-A416 WeakPolarHBondContact O-CB 3.1Å; Y412-A416 PolarHBondContact O-N 3.33Å
413	P	78.6	Confident	81.4	Confident	75 Å²	75	57.8 Å²	57.8	49%	0.487	29%	0.289	S	S	.	.	H	α-helix	trans	-58	-32.4	-167.9	18.7	-31.5	0	0	0	114.1	A417 F593	P413-A417 VanDerWaalsContact O-CB 3.31Å; P413-A417 WeakPolarHBondContact O-CB 3.32Å; P413-A417 PolarHBondContact O-N 3.02Å; P413-F593 HydrophobicContact CB-CZ 3.97Å; P413-F593 HydrophobicContact CG-CE1 4.3Å; P413-F593 HydrophobicContact CG-CZ 3.87Å
414	H	78.9	Confident	82.8	Confident	36 Å²	36	55.8 Å²	55.8	17%	0.167	28%	0.282	C	S	.	.	H	α-helix	trans	-63.9	-52.8	175.6	-172.2	113.3	0	0	0	111.7	Y412 A416 A417 F418 Y525 F593	Y412-H414 PolarHBondContact O-N 3.24Å; H414-A416 VanDerWaalsContact C-N 3.34Å; H414-A417 PolarHBondContact O-N 2.94Å; H414-F418 PolarHBondContact O-N 3.26Å; H414-Y525 PolarHBondContact CD2-OH 3.47Å; H414-Y525 AromaticContact NE2-CZ 3.83Å; H414-Y525 PolarHBondContact NE2-OH 3.33Å; H414-F593 HydrophobicContact CB-CD1 4.33Å; H414-F593 HydrophobicContact CB-CD2 4.22Å; H414-F593 HydrophobicContact CB-CE1 3.94Å; H414-F593 HydrophobicContact CB-CE2 3.8Å; H414-F593 HydrophobicContact CB-CG 4.48Å; H414-F593 HydrophobicContact CB-CZ 3.67Å; H414-F593 AromaticContact ND1-CD2 3.59Å; H414-F593 AromaticContact ND1-CG 3.63Å
415	Y	82.6	Confident	83.8	Confident	41 Å²	41	47 Å²	47	16%	0.161	24%	0.243	C	C	.	.	H	α-helix	trans	-67.5	-37.2	-179.8	-66	-45.9	0	0	0	111.8	F410 Y412 F418 L419 Y525 A529	F410-Y415 HydrophobicContact CD1-CG 4.16Å; F410-Y415 HydrophobicContact CE1-CD1 4.43Å; F410-Y415 HydrophobicContact CE1-CG 4.42Å; Y412-Y415 HydrophobicContact CD2-CD2 4.37Å; Y412-Y415 PolarHBondContact O-N 3.46Å; Y415-F418 WeakPolarHBondContact O-CB 3.47Å; Y415-F418 PolarHBondContact O-N 2.96Å; Y415-L419 WeakPolarHBondContact O-CB 3.43Å; Y415-L419 WeakPolarHBondContact O-CG 3.42Å; Y415-L419 PolarHBondContact O-N 3.19Å; Y415-Y525 AromaticContact CD1-CE1 3.93Å; Y415-Y525 HydrophobicContact CD1-CE1 3.93Å; Y415-Y525 HydrophobicContact CE1-CE1 4.14Å; Y415-Y525 WeakPolarHBondContact CE1-OH 3.45Å; Y415-A529 HydrophobicContact CD1-CB 4.14Å; Y415-A529 HydrophobicContact CE1-CB 3.44Å; Y415-A529 VanDerWaalsContact CE1-CB 3.44Å
416	A	86.5	Confident	84.9	Confident	42 Å²	42	45.6 Å²	45.6	35%	0.347	23%	0.232	S	C	.	.	H	α-helix	trans	-63.2	-43.5	174.4	0	0	0	0	0	111.7	F410 Y412 H414 L419 F420	F410-A416 PolarHBondContact O-N 3.04Å; Y412-A416 WeakPolarHBondContact O-CB 3.1Å; Y412-A416 PolarHBondContact O-N 3.33Å; H414-A416 VanDerWaalsContact C-N 3.34Å; A416-L419 PolarHBondContact O-N 3.09Å; A416-F420 VanDerWaalsContact O-CB 3.31Å; A416-F420 WeakPolarHBondContact O-CB 3.32Å; A416-F420 PolarHBondContact O-N 3.44Å
417	A	88.5	Confident	86.1	Confident	16 Å²	16	46.3 Å²	46.3	13%	0.132	24%	0.235	C	C	.	.	H	α-helix	trans	-63.2	-42.6	175.4	0	0	0	0	0	111.6	P413 H414 F420 V421 F585 I588	P413-A417 VanDerWaalsContact O-CB 3.31Å; P413-A417 WeakPolarHBondContact O-CB 3.32Å; P413-A417 PolarHBondContact O-N 3.02Å; H414-A417 PolarHBondContact O-N 2.94Å; A417-F420 PolarHBondContact O-N 2.9Å; A417-V421 WeakPolarHBondContact O-CG2 3.38Å; A417-V421 PolarHBondContact O-N 2.92Å; A417-F585 HydrophobicContact CB-CD2 4.19Å; A417-F585 HydrophobicContact CB-CE2 4.18Å; A417-I588 HydrophobicContact CB-CG2 4.2Å
418	F	89.5	Confident	86.9	Confident	2 Å²	2	42.1 Å²	42.1	1%	0.009	22%	0.215	C	C	.	.	H	α-helix	trans	-57.9	-52.4	173.8	-178.7	-86	0	0	0	111.5	H414 Y415 F420 V421 T422 L481 A522 Y525	H414-F418 PolarHBondContact O-N 3.26Å; Y415-F418 WeakPolarHBondContact O-CB 3.47Å; Y415-F418 PolarHBondContact O-N 2.96Å; F418-F420 VanDerWaalsContact C-N 3.32Å; F418-F420 PolarHBondContact O-N 3Å; F418-V421 PolarHBondContact O-N 3.19Å; F418-T422 HydrophobicContact CD1-CG2 4.16Å; F418-T422 HydrophobicContact CE1-CG2 3.52Å; F418-T422 HydrophobicContact CZ-CG2 3.73Å; F418-T422 WeakPolarHBondContact O-CG2 3.43Å; F418-T422 PolarHBondContact O-N 3.32Å; F418-L481 HydrophobicContact CD2-CD2 3.65Å; F418-L481 HydrophobicContact CE2-CD1 3.8Å; F418-L481 HydrophobicContact CE2-CD2 3.23Å; F418-L481 HydrophobicContact CE2-CG 4.17Å; F418-L481 HydrophobicContact CZ-CD1 4.13Å; F418-L481 HydrophobicContact CZ-CD2 3.78Å; F418-A522 HydrophobicContact CE1-CB 4.04Å; F418-A522 HydrophobicContact CZ-CB 3.67Å; F418-Y525 HydrophobicContact CB-CE1 4.08Å; F418-Y525 AromaticContact CD1-CD1 3.6Å; F418-Y525 HydrophobicContact CD1-CD1 3.6Å; F418-Y525 AromaticContact CD1-CE1 3.86Å; F418-Y525 HydrophobicContact CD1-CE1 3.86Å; F418-Y525 AromaticContact CD2-CD1 3.56Å; F418-Y525 HydrophobicContact CD2-CD1 3.56Å; F418-Y525 AromaticContact CD2-CE1 3.64Å; F418-Y525 HydrophobicContact CD2-CE1 3.64Å; F418-Y525 HydrophobicContact CD2-CG 4.12Å; F418-Y525 AromaticContact CE1-CD1 3.64Å; F418-Y525 HydrophobicContact CE1-CD1 3.64Å; F418-Y525 HydrophobicContact CE1-CE1 4.36Å; F418-Y525 HydrophobicContact CE1-CG 4.4Å; F418-Y525 AromaticContact CE2-CD1 3.56Å; F418-Y525 HydrophobicContact CE2-CD1 3.56Å; F418-Y525 HydrophobicContact CE2-CD2 4.5Å; F418-Y525 HydrophobicContact CE2-CE1 4.13Å; F418-Y525 AromaticContact CE2-CG 3.79Å; F418-Y525 HydrophobicContact CE2-CG 3.79Å; F418-Y525 AromaticContact CG-CD1 3.62Å; F418-Y525 HydrophobicContact CG-CD1 3.62Å; F418-Y525 AromaticContact CG-CE1 3.54Å; F418-Y525 HydrophobicContact CG-CE1 3.54Å; F418-Y525 AromaticContact CZ-CD1 3.68Å; F418-Y525 HydrophobicContact CZ-CD1 3.68Å; F418-Y525 HydrophobicContact CZ-CG 4.02Å
419	L	90.6	Very high	87.6	Confident	17 Å²	17	36 Å²	36	9%	0.089	19%	0.191	C	C	.	.	H	α-helix	trans	-61.3	-40	178.9	-74	-177.5	0	0	0	112	F410 Y415 A416 V421 T422 W423 I526 L541 L542 L545	F410-L419 HydrophobicContact CB-CD1 3.63Å; F410-L419 HydrophobicContact CD1-CD1 3.96Å; F410-L419 HydrophobicContact CD1-CG 4.4Å; F410-L419 HydrophobicContact CG-CD1 3.99Å; Y415-L419 WeakPolarHBondContact O-CB 3.43Å; Y415-L419 WeakPolarHBondContact O-CG 3.42Å; Y415-L419 PolarHBondContact O-N 3.19Å; A416-L419 PolarHBondContact O-N 3.09Å; L419-V421 PolarHBondContact O-N 2.88Å; L419-T422 WeakPolarHBondContact CA-OG1 3.39Å; L419-T422 PolarHBondContact O-N 2.85Å; L419-T422 PolarHBondContact O-OG1 3.03Å; L419-W423 WeakPolarHBondContact O-CB 3.4Å; L419-W423 PolarHBondContact O-N 3.4Å; L419-I526 HydrophobicContact CD2-CD1 3.96Å; L419-L541 HydrophobicContact CD1-CD2 4.34Å; L419-L542 HydrophobicContact CD2-CD1 4.18Å; L419-L545 HydrophobicContact CB-CD1 4.18Å; L419-L545 HydrophobicContact CD1-CD1 4.02Å; L419-L545 HydrophobicContact CD2-CD1 3.91Å; L419-L545 HydrophobicContact CG-CD1 4.27Å
420	F	93.6	Very high	88.7	Confident	98 Å²	98	34.3 Å²	34.3	43%	0.43	18%	0.181	S	C	.	.	H	α-helix	trans	-60.6	-45.2	176	179.5	-95.4	0	0	0	112	A416 A417 F418 T422 W423 W424 I581	A416-F420 VanDerWaalsContact O-CB 3.31Å; A416-F420 WeakPolarHBondContact O-CB 3.32Å; A416-F420 PolarHBondContact O-N 3.44Å; A417-F420 PolarHBondContact O-N 2.9Å; F418-F420 VanDerWaalsContact C-N 3.32Å; F418-F420 PolarHBondContact O-N 3Å; F420-T422 VanDerWaalsContact C-N 3.34Å; F420-T422 PolarHBondContact O-N 3.49Å; F420-W423 AromaticContact CD2-CE3 3.9Å; F420-W423 HydrophobicContact CD2-CE3 3.9Å; F420-W423 HydrophobicContact CD2-CZ3 4.13Å; F420-W423 AromaticContact CE2-CE3 3.76Å; F420-W423 HydrophobicContact CE2-CE3 3.76Å; F420-W423 AromaticContact CE2-CZ3 3.52Å; F420-W423 HydrophobicContact CE2-CZ3 3.52Å; F420-W423 HydrophobicContact CZ-CE3 4.4Å; F420-W423 HydrophobicContact CZ-CZ3 4.04Å; F420-W423 PolarHBondContact O-N 3.39Å; F420-W424 HydrophobicContact CZ-CE3 4.33Å; F420-W424 WeakPolarHBondContact O-CB 3.37Å; F420-W424 PolarHBondContact O-N 2.84Å; F420-I581 HydrophobicContact CE1-CD1 4.1Å; F420-I581 HydrophobicContact CE1-CG1 4.31Å
421	V	93.7	Very high	89.5	Confident	2 Å²	2	34 Å²	34	1%	0.012	18%	0.179	C	C	.	.	H	α-helix	trans	-61.7	-44.3	175.7	171.4	0	0	0	0	110.6	A417 F418 L419 W423 W424 M425 L481 L485 I581 F585	A417-V421 WeakPolarHBondContact O-CG2 3.38Å; A417-V421 PolarHBondContact O-N 2.92Å; F418-V421 PolarHBondContact O-N 3.19Å; L419-V421 PolarHBondContact O-N 2.88Å; V421-W423 PolarHBondContact O-N 3.4Å; V421-W424 PolarHBondContact O-N 3Å; V421-M425 HydrophobicContact CG1-CG 4.46Å; V421-M425 HydrophobicContact CG1-SD 4.12Å; V421-M425 VanDerWaalsContact O-CG 3.3Å; V421-M425 WeakPolarHBondContact O-CG 3.46Å; V421-M425 PolarHBondContact O-N 2.87Å; V421-L481 HydrophobicContact CB-CD2 4.3Å; V421-L481 HydrophobicContact CG1-CD2 3.86Å; V421-L481 HydrophobicContact CG1-CG 4.39Å; V421-L485 HydrophobicContact CG1-CD1 3.78Å; V421-L485 HydrophobicContact CG1-CD2 4.26Å; V421-L485 HydrophobicContact CG1-CG 4.1Å; V421-L485 HydrophobicContact CG2-CD1 4.49Å; V421-I581 HydrophobicContact CG2-CG2 4.03Å; V421-F585 HydrophobicContact CG2-CB 4.02Å; V421-F585 HydrophobicContact CG2-CD1 3.91Å; V421-F585 HydrophobicContact CG2-CD2 3.74Å; V421-F585 HydrophobicContact CG2-CE1 4.33Å; V421-F585 HydrophobicContact CG2-CE2 4.14Å; V421-F585 HydrophobicContact CG2-CG 3.63Å; V421-F585 HydrophobicContact CG2-CZ 4.43Å
422	T	92	Very high	90.3	Very high	1 Å²	1	31.4 Å²	31.4	1%	0.006	16%	0.157	C	C	.	.	H	α-helix	trans	-63.1	-41.4	177.6	61.7	0	0	0	0	112.2	F418 L419 F420 M425 G426 L481 A522 L542 H546	F418-T422 HydrophobicContact CD1-CG2 4.16Å; F418-T422 HydrophobicContact CE1-CG2 3.52Å; F418-T422 HydrophobicContact CZ-CG2 3.73Å; F418-T422 WeakPolarHBondContact O-CG2 3.43Å; F418-T422 PolarHBondContact O-N 3.32Å; L419-T422 WeakPolarHBondContact CA-OG1 3.39Å; L419-T422 PolarHBondContact O-N 2.85Å; L419-T422 PolarHBondContact O-OG1 3.03Å; F420-T422 VanDerWaalsContact C-N 3.34Å; F420-T422 PolarHBondContact O-N 3.49Å; T422-M425 PolarHBondContact O-N 3.23Å; T422-G426 PolarHBondContact O-N 2.96Å; T422-L481 HydrophobicContact CG2-CD2 4.33Å; T422-A522 HydrophobicContact CG2-CB 3.75Å; T422-L542 HydrophobicContact CG2-CD1 4.01Å; T422-H546 PolarHBondContact O-ND1 2.97Å
423	W	94.3	Very high	91	Very high	51 Å²	51	26.1 Å²	26.1	19%	0.193	14%	0.137	C	C	.	.	H	α-helix	trans	-61.1	-45.3	173.8	168	76	0	0	0	111.7	L419 F420 V421 M425 G426 L427	L419-W423 WeakPolarHBondContact O-CB 3.4Å; L419-W423 PolarHBondContact O-N 3.4Å; F420-W423 AromaticContact CD2-CE3 3.9Å; F420-W423 HydrophobicContact CD2-CE3 3.9Å; F420-W423 HydrophobicContact CD2-CZ3 4.13Å; F420-W423 AromaticContact CE2-CE3 3.76Å; F420-W423 HydrophobicContact CE2-CE3 3.76Å; F420-W423 AromaticContact CE2-CZ3 3.52Å; F420-W423 HydrophobicContact CE2-CZ3 3.52Å; F420-W423 HydrophobicContact CZ-CE3 4.4Å; F420-W423 HydrophobicContact CZ-CZ3 4.04Å; F420-W423 PolarHBondContact O-N 3.39Å; V421-W423 PolarHBondContact O-N 3.4Å; W423-M425 VanDerWaalsContact C-N 3.32Å; W423-M425 PolarHBondContact O-N 2.8Å; W423-G426 WeakPolarHBondContact O-CA 3.48Å; W423-G426 PolarHBondContact O-N 3.38Å; W423-L427 HydrophobicContact CH2-CD1 4.39Å; W423-L427 HydrophobicContact CZ2-CD1 4.45Å; W423-L427 PolarHBondContact O-N 2.93Å
424	W	95.8	Very high	91.7	Very high	45 Å²	45	22.7 Å²	22.7	17%	0.17	11%	0.114	C	C	.	.	H	α-helix	trans	-60.3	-41.8	177.5	-172.8	-90	0	0	0	112.1	F420 V421 G426 L427 G428 Y574 A577 C578 I581	F420-W424 HydrophobicContact CZ-CE3 4.33Å; F420-W424 WeakPolarHBondContact O-CB 3.37Å; F420-W424 PolarHBondContact O-N 2.84Å; V421-W424 PolarHBondContact O-N 3Å; W424-G426 VanDerWaalsContact C-N 3.27Å; W424-G426 PolarHBondContact O-N 3.47Å; W424-L427 HydrophobicContact CE3-CD1 4.39Å; W424-L427 HydrophobicContact CZ3-CD1 4.33Å; W424-L427 WeakPolarHBondContact O-CA 3.28Å; W424-L427 WeakPolarHBondContact O-CB 3.31Å; W424-L427 PolarHBondContact O-N 3.27Å; W424-L427 VanDerWaalsContact O-N 3.09Å; W424-G428 PolarHBondContact O-N 3.27Å; W424-Y574 AromaticContact CE2-CE2 3.79Å; W424-Y574 HydrophobicContact CZ2-CD2 4.09Å; W424-Y574 HydrophobicContact CZ2-CE2 4.11Å; W424-Y574 AromaticContact NE1-CE2 3.39Å; W424-Y574 AromaticContact NE1-CZ 3.68Å; W424-Y574 PolarHBondContact O-OH 3.49Å; W424-A577 HydrophobicContact CH2-CB 4.03Å; W424-A577 HydrophobicContact CZ2-CB 3.43Å; W424-A577 VanDerWaalsContact CZ2-CB 3.43Å; W424-C578 PolarHBondContact NE1-SG 3.17Å; W424-C578 VanDerWaalsContact NE1-SG 3.4Å; W424-I581 HydrophobicContact CB-CD1 4.21Å; W424-I581 HydrophobicContact CD2-CD1 3.06Å; W424-I581 HydrophobicContact CE3-CD1 3.5Å; W424-I581 VanDerWaalsContact CE3-CD1 3.5Å; W424-I581 HydrophobicContact CG-CD1 3.36Å; W424-I581 HydrophobicContact CH2-CD1 4.14Å; W424-I581 HydrophobicContact CZ2-CD1 3.81Å; W424-I581 HydrophobicContact CZ3-CD1 4Å
425	M	93.7	Very high	92.6	Very high	3 Å²	3	21 Å²	21	2%	0.015	11%	0.106	C	C	.	.	H	α-helix	trans	-64.3	-35.1	175.1	-66.8	-177.3	76.6	0	0	111.8	V421 T422 W423 L427 G428 V429 L485 N488 T514 V518	V421-M425 HydrophobicContact CG1-CG 4.46Å; V421-M425 HydrophobicContact CG1-SD 4.12Å; V421-M425 VanDerWaalsContact O-CG 3.3Å; V421-M425 WeakPolarHBondContact O-CG 3.46Å; V421-M425 PolarHBondContact O-N 2.87Å; T422-M425 PolarHBondContact O-N 3.23Å; W423-M425 VanDerWaalsContact C-N 3.32Å; W423-M425 PolarHBondContact O-N 2.8Å; M425-L427 VanDerWaalsContact C-N 3.29Å; M425-L427 PolarHBondContact O-N 2.87Å; M425-G428 PolarHBondContact O-N 2.88Å; M425-V429 PolarHBondContact O-N 3.34Å; M425-V429 VanDerWaalsContact O-N 3.11Å; M425-L485 HydrophobicContact CG-CD2 4.03Å; M425-L485 HydrophobicContact SD-CD2 4.32Å; M425-L485 HydrophobicContact SD-CG 4.36Å; M425-N488 WeakPolarHBondContact CE-ND2 3.43Å; M425-T514 WeakPolarHBondContact CE-O 3.23Å; M425-V518 HydrophobicContact CE-CB 3.95Å; M425-V518 HydrophobicContact CE-CG1 3.47Å; M425-V518 VanDerWaalsContact CE-CG1 3.47Å; M425-V518 HydrophobicContact CE-CG2 3.6Å; M425-V518 HydrophobicContact SD-CG1 3.53Å; M425-V518 VanDerWaalsContact SD-CG1 3.53Å
426	G	93.5	Very high	93.1	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-60.7	-37.2	171	0	0	0	0	0	112.6	T422 W423 W424 G428 V429 G430 H546 G550 R551	T422-G426 PolarHBondContact O-N 2.96Å; W423-G426 WeakPolarHBondContact O-CA 3.48Å; W423-G426 PolarHBondContact O-N 3.38Å; W424-G426 VanDerWaalsContact C-N 3.27Å; W424-G426 PolarHBondContact O-N 3.47Å; G426-G428 VanDerWaalsContact C-N 3.34Å; G426-G428 PolarHBondContact O-N 2.83Å; G426-V429 WeakPolarHBondContact O-CB 3.28Å; G426-V429 PolarHBondContact O-N 3.06Å; G426-G430 PolarHBondContact O-N 3.16Å; G426-H546 WeakPolarHBondContact CA-O 3.26Å; G426-H546 PolarHBondContact N-CE1 3.04Å; G426-H546 VanDerWaalsContact N-CE1 3.32Å; G426-H546 PolarHBondContact N-ND1 3.14Å; G426-G550 CarbonylContact O-C 3.59Å; G426-R551 VanDerWaalsContact O-CA 3.27Å; G426-R551 WeakPolarHBondContact O-CA 3.33Å; G426-R551 PolarHBondContact O-N 3.21Å
427	L	95.4	Very high	93.5	Very high	16 Å²	16	18.2 Å²	18.2	8%	0.084	9%	0.088	C	C	.	.	H	α-helix	trans	-57.7	-45.5	172.5	-163.9	162.4	0	0	0	111.2	W423 W424 M425 V429 G430 L431 G550 G554 Y574	W423-L427 HydrophobicContact CH2-CD1 4.39Å; W423-L427 HydrophobicContact CZ2-CD1 4.45Å; W423-L427 PolarHBondContact O-N 2.93Å; W424-L427 HydrophobicContact CE3-CD1 4.39Å; W424-L427 HydrophobicContact CZ3-CD1 4.33Å; W424-L427 WeakPolarHBondContact O-CA 3.28Å; W424-L427 WeakPolarHBondContact O-CB 3.31Å; W424-L427 PolarHBondContact O-N 3.27Å; W424-L427 VanDerWaalsContact O-N 3.09Å; M425-L427 VanDerWaalsContact C-N 3.29Å; M425-L427 PolarHBondContact O-N 2.87Å; L427-V429 PolarHBondContact O-N 3.13Å; L427-G430 PolarHBondContact O-N 3.21Å; L427-L431 HydrophobicContact CD2-CD1 3.62Å; L427-L431 HydrophobicContact CD2-CG 4.04Å; L427-L431 PolarHBondContact O-N 3.22Å; L427-G550 VanDerWaalsContact CA-O 3.26Å; L427-G550 WeakPolarHBondContact CA-O 3.48Å; L427-G550 PolarHBondContact N-O 2.91Å; L427-G554 VanDerWaalsContact O-CA 3.28Å; L427-G554 WeakPolarHBondContact O-CA 3.33Å; L427-Y574 HydrophobicContact CB-CE2 4.41Å; L427-Y574 HydrophobicContact CD2-CD2 3.84Å; L427-Y574 HydrophobicContact CD2-CE2 3.73Å
428	G	95	Very high	93.8	Very high	3 Å²	3	17.5 Å²	17.5	3%	0.031	8%	0.082	C	C	.	.	H	α-helix	trans	-60.3	-42.8	174.3	0	0	0	0	0	113.5	W424 M425 G426 G430 L431 V432 Y574	W424-G428 PolarHBondContact O-N 3.27Å; M425-G428 PolarHBondContact O-N 2.88Å; G426-G428 VanDerWaalsContact C-N 3.34Å; G426-G428 PolarHBondContact O-N 2.83Å; G428-G430 VanDerWaalsContact C-N 3.28Å; G428-G430 PolarHBondContact O-N 2.82Å; G428-L431 PolarHBondContact O-N 3.47Å; G428-V432 PolarHBondContact O-N 3.41Å; G428-Y574 WeakPolarHBondContact CA-OH 3.17Å; G428-Y574 PolarHBondContact N-OH 3.44Å
429	V	92.6	Very high	94	Very high	38 Å²	38	17.4 Å²	17.4	23%	0.23	8%	0.081	C	C	.	.	H	α-helix	trans	-59.2	-42.6	175	175.6	0	0	0	0	110.4	M425 G426 L427 F433	M425-V429 PolarHBondContact O-N 3.34Å; M425-V429 VanDerWaalsContact O-N 3.11Å; G426-V429 WeakPolarHBondContact O-CB 3.28Å; G426-V429 PolarHBondContact O-N 3.06Å; L427-V429 PolarHBondContact O-N 3.13Å; V429-F433 WeakPolarHBondContact O-CB 3.18Å; V429-F433 PolarHBondContact O-N 3.07Å
430	G	93.4	Very high	94.1	Very high	1 Å²	1	16.6 Å²	16.6	1%	0.01	8%	0.077	C	C	.	.	H	α-helix	trans	-60.8	-44.5	174.5	0	0	0	0	0	114	G426 L427 G428 F433 C434 R551	G426-G430 PolarHBondContact O-N 3.16Å; L427-G430 PolarHBondContact O-N 3.21Å; G428-G430 VanDerWaalsContact C-N 3.28Å; G428-G430 PolarHBondContact O-N 2.82Å; G430-F433 PolarHBondContact O-N 3.43Å; G430-C434 WeakPolarHBondContact O-CB 3.26Å; G430-C434 PolarHBondContact O-N 3.22Å; G430-R551 VanDerWaalsContact CA-O 3.26Å; G430-R551 WeakPolarHBondContact CA-O 3.23Å
431	L	95.8	Very high	94	Very high	4 Å²	4	13 Å²	13	2%	0.021	6%	0.061	C	C	.	.	H	α-helix	trans	-60.9	-49	177.1	-80.1	170.8	0	0	0	112.2	L427 G428 F435 F492 G554 V570 Y574	L427-L431 HydrophobicContact CD2-CD1 3.62Å; L427-L431 HydrophobicContact CD2-CG 4.04Å; L427-L431 PolarHBondContact O-N 3.22Å; G428-L431 PolarHBondContact O-N 3.47Å; L431-F435 HydrophobicContact CD2-CD2 4.41Å; L431-F435 WeakPolarHBondContact O-CB 3.5Å; L431-F435 PolarHBondContact O-N 3.32Å; L431-F492 HydrophobicContact CB-CE1 4.17Å; L431-F492 HydrophobicContact CB-CZ 4.44Å; L431-F492 HydrophobicContact CD1-CE1 4.28Å; L431-G554 VanDerWaalsContact CD2-O 3.28Å; L431-G554 WeakPolarHBondContact CD2-O 3.48Å; L431-V570 HydrophobicContact CD2-CG1 3.92Å; L431-Y574 HydrophobicContact CD1-CD2 3.53Å; L431-Y574 HydrophobicContact CD1-CE2 4.18Å; L431-Y574 HydrophobicContact CD1-CG 3.77Å
432	V	93.6	Very high	93.8	Very high	16 Å²	16	14.2 Å²	14.2	10%	0.097	7%	0.068	C	C	.	.	H	α-helix	trans	-64.3	-48.2	178.7	169.7	0	0	0	0	109.9	G428 C434 F435 L436 F492	G428-V432 PolarHBondContact O-N 3.41Å; V432-C434 VanDerWaalsContact C-N 3.27Å; V432-C434 PolarHBondContact O-N 3.34Å; V432-F435 PolarHBondContact O-N 2.94Å; V432-L436 HydrophobicContact CG1-CB 3.96Å; V432-L436 HydrophobicContact CG1-CD2 3.83Å; V432-L436 HydrophobicContact CG1-CG 4.42Å; V432-L436 WeakPolarHBondContact O-CB 3.5Å; V432-L436 PolarHBondContact O-N 2.86Å; V432-F492 HydrophobicContact CG2-CE1 3.98Å; V432-F492 HydrophobicContact CG2-CE2 4.15Å; V432-F492 HydrophobicContact CG2-CZ 3.52Å
433	F	92.5	Very high	93.7	Very high	42 Å²	42	15.3 Å²	15.3	18%	0.184	7%	0.074	C	C	.	.	H	α-helix	trans	-58.9	-38.3	-178	-174.5	-95.2	0	0	0	112.7	F82 V103 W302 V429 G430 R551	F82-F433 HydrophobicContact CB-CZ 4.07Å; V103-F433 HydrophobicContact CG1-CD1 3.98Å; V103-F433 HydrophobicContact CG1-CE1 4.01Å; W302-F433 HydrophobicContact CH2-CE2 4.27Å; W302-F433 HydrophobicContact CZ2-CE2 4.19Å; V429-F433 WeakPolarHBondContact O-CB 3.18Å; V429-F433 PolarHBondContact O-N 3.07Å; G430-F433 PolarHBondContact O-N 3.43Å; F433-R551 VanDerWaalsContact CD2-NH2 3.29Å
434	C	95	Very high	93.3	Very high	2 Å²	2	15.8 Å²	15.8	1%	0.014	9%	0.094	C	C	.	.	H	α-helix	trans	-88.6	-35.9	-178.8	-165.7	0	0	0	0	113.5	S86 V103 G430 V432 A555	S86-C434 WeakPolarHBondContact CB-O 3.24Å; S86-C434 PolarHBondContact OG-O 3.45Å; V103-C434 HydrophobicContact CG1-CB 4.23Å; G430-C434 WeakPolarHBondContact O-CB 3.26Å; G430-C434 PolarHBondContact O-N 3.22Å; V432-C434 VanDerWaalsContact C-N 3.27Å; V432-C434 PolarHBondContact O-N 3.34Å; C434-A555 HydrophobicContact CB-CB 3.99Å
435	F	96.4	Very high	93	Very high	0 Å²	0	14 Å²	14	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-123.5	-2	-165.7	-59.5	-68.5	0	0	0	115.8	P96 L431 V432 W438 H439 A555 G559 I562 T567 F571	P96-F435 HydrophobicContact CB-CE1 3.89Å; P96-F435 HydrophobicContact CB-CZ 4.42Å; L431-F435 HydrophobicContact CD2-CD2 4.41Å; L431-F435 WeakPolarHBondContact O-CB 3.5Å; L431-F435 PolarHBondContact O-N 3.32Å; V432-F435 PolarHBondContact O-N 2.94Å; F435-W438 HydrophobicContact CB-CB 4.46Å; F435-W438 HydrophobicContact CD1-CB 4.29Å; F435-W438 HydrophobicContact CD1-CD2 4.25Å; F435-W438 HydrophobicContact CD1-CE3 4.43Å; F435-W438 HydrophobicContact CD1-CG 4.22Å; F435-H439 WeakPolarHBondContact O-CB 3.38Å; F435-H439 PolarHBondContact O-N 3.09Å; F435-A555 WeakPolarHBondContact CE2-O 3.42Å; F435-G559 VanDerWaalsContact CE2-N 3.27Å; F435-I562 HydrophobicContact CB-CD1 3.67Å; F435-I562 HydrophobicContact CD1-CD1 3.52Å; F435-I562 HydrophobicContact CD2-CD1 3.39Å; F435-I562 HydrophobicContact CE1-CD1 3.97Å; F435-I562 HydrophobicContact CE2-CD1 3.86Å; F435-I562 HydrophobicContact CG-CD1 3.21Å; F435-I562 HydrophobicContact CZ-CD1 4.13Å; F435-T567 HydrophobicContact CB-CG2 4.49Å; F435-F571 HydrophobicContact CB-CZ 4.24Å
436	L	94.5	Very high	92.9	Very high	5 Å²	5	15.4 Å²	15.4	3%	0.026	10%	0.1	C	C	.	.	H	α-helix	trans	-61.4	-58	176	176.9	65.6	0	0	0	110.9	V432 W438 H439 L440 I495 V504 E508	V432-L436 HydrophobicContact CG1-CB 3.96Å; V432-L436 HydrophobicContact CG1-CD2 3.83Å; V432-L436 HydrophobicContact CG1-CG 4.42Å; V432-L436 WeakPolarHBondContact O-CB 3.5Å; V432-L436 PolarHBondContact O-N 2.86Å; L436-W438 VanDerWaalsContact C-N 3.27Å; L436-W438 PolarHBondContact O-N 3.26Å; L436-H439 WeakPolarHBondContact O-CB 3.31Å; L436-H439 PolarHBondContact O-N 2.68Å; L436-H439 VanDerWaalsContact O-N 3.11Å; L436-L440 HydrophobicContact CD1-CG 4.49Å; L436-L440 HydrophobicContact CG-CD1 4.42Å; L436-L440 WeakPolarHBondContact O-CG 3.46Å; L436-L440 PolarHBondContact O-N 3.36Å; L436-I495 HydrophobicContact CD1-CD1 4.04Å; L436-I495 HydrophobicContact CD1-CG2 4.2Å; L436-V504 HydrophobicContact CD1-CG2 4.38Å; L436-E508 WeakPolarHBondContact CD2-OE1 3.42Å
437	F	94.5	Very high	92.8	Very high	20 Å²	20	15.8 Å²	15.8	9%	0.088	10%	0.103	C	C	.	.	H	α-helix	trans	-70.5	-27.8	-179	-58.5	-21.4	0	0	0	112.2	P83 L84 I87 M306 H439 L440 Q441 Y450 A453	P83-F437 HydrophobicContact CB-CD2 4.27Å; P83-F437 HydrophobicContact CB-CE2 3.65Å; P83-F437 VanDerWaalsContact O-CD2 3.24Å; P83-F437 WeakPolarHBondContact O-CD2 3.37Å; L84-F437 HydrophobicContact CD2-CD2 4.28Å; I87-F437 HydrophobicContact CD1-CB 3.34Å; I87-F437 HydrophobicContact CD1-CG 4.43Å; I87-F437 HydrophobicContact CG1-CB 4.09Å; M306-F437 HydrophobicContact CE-CE2 3.83Å; M306-F437 HydrophobicContact CE-CZ 4.47Å; F437-H439 VanDerWaalsContact C-N 3.3Å; F437-H439 PolarHBondContact O-N 3.26Å; F437-L440 HydrophobicContact CD1-CD1 4Å; F437-L440 HydrophobicContact CE1-CD1 4.47Å; F437-L440 PolarHBondContact O-N 2.98Å; F437-Q441 WeakPolarHBondContact O-CB 3.41Å; F437-Q441 PolarHBondContact O-N 2.99Å; F437-Y450 HydrophobicContact CB-CD1 4.33Å; F437-Y450 HydrophobicContact CB-CD2 4.19Å; F437-Y450 HydrophobicContact CB-CE2 4.31Å; F437-Y450 HydrophobicContact CB-CG 4.21Å; F437-Y450 AromaticContact CD1-CD1 3.88Å; F437-Y450 HydrophobicContact CD1-CD1 3.88Å; F437-Y450 AromaticContact CD1-CG 3.96Å; F437-Y450 HydrophobicContact CD1-CG 3.96Å; F437-Y450 HydrophobicContact CD2-CD2 4.29Å; F437-Y450 HydrophobicContact CD2-CG 4.09Å; F437-Y450 HydrophobicContact CE1-CD1 4.36Å; F437-Y450 HydrophobicContact CE1-CG 4.3Å; F437-Y450 HydrophobicContact CE2-CG 4.42Å; F437-Y450 HydrophobicContact CG-CD1 4.12Å; F437-Y450 HydrophobicContact CG-CD2 4.2Å; F437-Y450 AromaticContact CG-CG 3.86Å; F437-Y450 HydrophobicContact CG-CG 3.86Å; F437-A453 HydrophobicContact CE1-CB 4.38Å
438	W	94.5	Very high	92.6	Very high	1 Å²	1	16.3 Å²	16.3	0%	0.004	11%	0.108	C	C	.	.	H	α-helix	trans	-57.1	-44.6	168.6	-170.6	-65.6	0	0	0	111.8	S86 K90 P96 A99 G214 F435 L436	S86-W438 WeakPolarHBondContact O-CZ3 3.41Å; S86-W438 VanDerWaalsContact OG-CE3 3.3Å; K90-W438 HydrophobicContact CB-CD2 4.35Å; K90-W438 HydrophobicContact CB-CE3 3.88Å; K90-W438 HydrophobicContact CB-CH2 3.61Å; K90-W438 HydrophobicContact CB-CZ2 4.1Å; K90-W438 HydrophobicContact CB-CZ3 3.49Å; K90-W438 VanDerWaalsContact CB-CZ3 3.49Å; K90-W438 HydrophobicContact CD-CD2 3.7Å; K90-W438 HydrophobicContact CD-CE3 4.04Å; K90-W438 HydrophobicContact CD-CG 4.17Å; K90-W438 HydrophobicContact CD-CH2 4.24Å; K90-W438 HydrophobicContact CD-CZ2 3.91Å; K90-W438 HydrophobicContact CD-CZ3 4.31Å; K90-W438 HydrophobicContact CG-CD2 4.23Å; K90-W438 HydrophobicContact CG-CE3 4.24Å; K90-W438 HydrophobicContact CG-CH2 3.68Å; K90-W438 HydrophobicContact CG-CZ2 3.64Å; K90-W438 HydrophobicContact CG-CZ3 3.99Å; K90-W438 PolarHBondContact NZ-O 3.09Å; P96-W438 HydrophobicContact CB-CZ2 4.23Å; P96-W438 HydrophobicContact CG-CH2 4.37Å; P96-W438 HydrophobicContact CG-CZ2 3.64Å; A99-W438 HydrophobicContact CB-CH2 4Å; A99-W438 HydrophobicContact CB-CZ3 3.55Å; G214-W438 PolarHBondContact O-NE1 3.26Å; F435-W438 HydrophobicContact CB-CB 4.46Å; F435-W438 HydrophobicContact CD1-CB 4.29Å; F435-W438 HydrophobicContact CD1-CD2 4.25Å; F435-W438 HydrophobicContact CD1-CE3 4.43Å; F435-W438 HydrophobicContact CD1-CG 4.22Å; L436-W438 VanDerWaalsContact C-N 3.27Å; L436-W438 PolarHBondContact O-N 3.26Å
439	H	94.4	Very high	92.6	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-68.4	-47.5	176.2	-179.7	67.9	0	0	0	111.7	F435 L436 F437 Q441 D442 I443 I495 T567 F571	F435-H439 WeakPolarHBondContact O-CB 3.38Å; F435-H439 PolarHBondContact O-N 3.09Å; L436-H439 WeakPolarHBondContact O-CB 3.31Å; L436-H439 PolarHBondContact O-N 2.68Å; L436-H439 VanDerWaalsContact O-N 3.11Å; F437-H439 VanDerWaalsContact C-N 3.3Å; F437-H439 PolarHBondContact O-N 3.26Å; H439-Q441 VanDerWaalsContact C-N 3.29Å; H439-Q441 PolarHBondContact O-N 3.02Å; H439-D442 PolarHBondContact O-N 3.38Å; H439-D442 VanDerWaalsContact O-N 3.12Å; H439-I443 PolarHBondContact O-N 3.14Å; H439-I495 PolarHBondContact NE2-O 3.13Å; H439-T567 HydrophobicContact CB-CG2 4.06Å; H439-T567 WeakPolarHBondContact ND1-CB 3.5Å; H439-T567 PolarHBondContact ND1-OG1 3.17Å; H439-F571 HydrophobicContact CB-CE2 3.75Å; H439-F571 HydrophobicContact CB-CZ 4.35Å; H439-F571 AromaticContact CG-CE2 3.79Å
440	L	92.9	Very high	92.6	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-59.4	-40.2	179.9	-67	-176.7	0	0	0	111.8	L436 F437 D442 I443 G444 G445 L449 Y450 P501 V504	L436-L440 HydrophobicContact CD1-CG 4.49Å; L436-L440 HydrophobicContact CG-CD1 4.42Å; L436-L440 WeakPolarHBondContact O-CG 3.46Å; L436-L440 PolarHBondContact O-N 3.36Å; F437-L440 HydrophobicContact CD1-CD1 4Å; F437-L440 HydrophobicContact CE1-CD1 4.47Å; F437-L440 PolarHBondContact O-N 2.98Å; L440-D442 VanDerWaalsContact C-N 3.3Å; L440-D442 PolarHBondContact O-N 3.3Å; L440-I443 HydrophobicContact CD2-CD1 4Å; L440-I443 CarbonylContact O-C 3.44Å; L440-I443 VanDerWaalsContact O-CG1 3.26Å; L440-I443 WeakPolarHBondContact O-CG1 3.25Å; L440-I443 PolarHBondContact O-N 3.01Å; L440-G444 PolarHBondContact O-N 2.82Å; L440-G445 WeakPolarHBondContact O-CA 3.33Å; L440-G445 PolarHBondContact O-N 3Å; L440-L449 HydrophobicContact CD1-CD2 4.34Å; L440-Y450 HydrophobicContact CB-CD1 4.32Å; L440-Y450 HydrophobicContact CB-CE1 3.63Å; L440-Y450 HydrophobicContact CD1-CD1 4.02Å; L440-Y450 HydrophobicContact CD1-CE1 4.16Å; L440-P501 HydrophobicContact CD2-CB 4.37Å; L440-V504 HydrophobicContact CD1-CB 4.44Å; L440-V504 HydrophobicContact CD1-CG1 3.99Å; L440-V504 HydrophobicContact CD1-CG2 4.3Å; L440-V504 HydrophobicContact CD2-CB 4.09Å; L440-V504 HydrophobicContact CD2-CG1 4.36Å; L440-V504 HydrophobicContact CD2-CG2 4.17Å
441	Q	91.6	Very high	92.6	Very high	22 Å²	22	14.4 Å²	14.4	10%	0.103	10%	0.095	C	C	.	.	H	α-helix	trans	-59.5	-40.1	176.5	-163.4	-169.8	29.4	0	0	112.3	H241 F437 H439 I443 G444 Y450	H241-Q441 VanDerWaalsContact CD2-CD 3.49Å; H241-Q441 PolarHBondContact CE1-O 2.82Å; F437-Q441 WeakPolarHBondContact O-CB 3.41Å; F437-Q441 PolarHBondContact O-N 2.99Å; H439-Q441 VanDerWaalsContact C-N 3.29Å; H439-Q441 PolarHBondContact O-N 3.02Å; Q441-I443 VanDerWaalsContact C-N 3.29Å; Q441-I443 PolarHBondContact O-N 3.13Å; Q441-G444 PolarHBondContact O-N 2.95Å; Q441-Y450 WeakPolarHBondContact CA-OH 3.47Å; Q441-Y450 WeakPolarHBondContact CB-OH 3.46Å; Q441-Y450 PolarHBondContact N-OH 3.08Å
442	D	89.5	Confident	92.6	Very high	29 Å²	29	16.9 Å²	16.9	16%	0.155	11%	0.108	C	C	.	.	H	α-helix	trans	-72.3	-21.8	-179.5	-74	-20.7	0	0	0	113.7	K90 P213 G214 H241 H439 L440	K90-D442 IonicContact NZ-OD1 3.79Å; K90-D442 PolarHBondContact NZ-OD1 3.05Å; K90-D442 IonicContact NZ-OD2 3.51Å; K90-D442 PolarHBondContact NZ-OD2 2.62Å; P213-D442 HydrophobicContact CB-CB 3.9Å; G214-D442 WeakPolarHBondContact CA-OD2 3.39Å; G214-D442 PolarHBondContact N-OD2 2.94Å; H241-D442 IonicContact NE2-OD1 3.87Å; H241-D442 PolarHBondContact NE2-OD1 3.03Å; H439-D442 PolarHBondContact O-N 3.38Å; H439-D442 VanDerWaalsContact O-N 3.12Å; L440-D442 VanDerWaalsContact C-N 3.3Å; L440-D442 PolarHBondContact O-N 3.3Å
443	I	88.9	Confident	92.6	Very high	24 Å²	24	16.1 Å²	16.1	12%	0.123	10%	0.103	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.6	9.9	172.8	63.2	166.4	0	0	0	112.7	P213 H439 L440 Q441 L498 P501	P213-I443 HydrophobicContact CB-CG2 4.46Å; P213-I443 HydrophobicContact CG-CG2 4.13Å; H439-I443 PolarHBondContact O-N 3.14Å; L440-I443 HydrophobicContact CD2-CD1 4Å; L440-I443 CarbonylContact O-C 3.44Å; L440-I443 VanDerWaalsContact O-CG1 3.26Å; L440-I443 WeakPolarHBondContact O-CG1 3.25Å; L440-I443 PolarHBondContact O-N 3.01Å; Q441-I443 VanDerWaalsContact C-N 3.29Å; Q441-I443 PolarHBondContact O-N 3.13Å; I443-L498 HydrophobicContact CD1-CB 4.05Å; I443-P501 HydrophobicContact CD1-CB 3.98Å; I443-P501 HydrophobicContact CG1-CB 4.04Å; I443-P501 WeakPolarHBondContact O-CD 3.21Å
444	G	86.4	Confident	92.5	Very high	61 Å²	61	14.4 Å²	14.4	63%	0.629	10%	0.097	S	C	*	.	T	Hydrogen-bonded Turn	trans	95	14.5	173	0	0	0	0	0	116.2	L440 Q441	L440-G444 PolarHBondContact O-N 2.82Å; Q441-G444 PolarHBondContact O-N 2.95Å
445	G	89.7	Confident	92.4	Very high	7 Å²	7	16.4 Å²	16.4	7%	0.072	11%	0.109	C	C	.	.			trans	-69.1	134.5	177.6	0	0	0	0	0	111.8	L440 Y450	L440-G445 WeakPolarHBondContact O-CA 3.33Å; L440-G445 PolarHBondContact O-N 3Å; G445-Y450 PolarHBondContact O-OH 2.79Å
446	S	90.9	Very high	92.2	Very high	32 Å²	32	17.5 Å²	17.5	22%	0.224	11%	0.114	C	C	.	.			trans	-85.9	155.9	177.8	70.8	0	0	0	0	112.8	D314 S448 L449 Y450	D314-S446 PolarHBondContact OD2-OG 3.47Å; S446-S448 VanDerWaalsContact C-N 3.26Å; S446-S448 PolarHBondContact O-N 3.17Å; S446-L449 VanDerWaalsContact O-CB 3.23Å; S446-L449 WeakPolarHBondContact O-CB 3.23Å; S446-L449 PolarHBondContact O-N 3.35Å; S446-Y450 WeakPolarHBondContact O-CD1 3.39Å; S446-Y450 WeakPolarHBondContact O-CE1 3.26Å; S446-Y450 PolarHBondContact O-N 2.99Å
447	P	91	Very high	92	Very high	9 Å²	9	17.8 Å²	17.8	6%	0.058	12%	0.116	C	C	.	.	H	α-helix	trans	-46	-39.6	167.6	-33.5	32.4	0	0	0	116.1	G310 L313 D314 K331 L449 Y450 G451	G310-P447 VanDerWaalsContact CA-O 3.32Å; G310-P447 WeakPolarHBondContact CA-O 3.35Å; G310-P447 CarbonylContact O-C 3.57Å; G310-P447 VanDerWaalsContact O-CB 3.26Å; G310-P447 WeakPolarHBondContact O-CB 3.44Å; L313-P447 HydrophobicContact CB-CB 3.69Å; L313-P447 HydrophobicContact CB-CG 4.05Å; L313-P447 HydrophobicContact CD1-CB 4.37Å; D314-P447 WeakPolarHBondContact OD1-CD 3.39Å; D314-P447 WeakPolarHBondContact OD1-CG 3.29Å; K331-P447 HydrophobicContact CD-CG 4.49Å; K331-P447 HydrophobicContact CG-CG 4.13Å; P447-L449 VanDerWaalsContact C-N 3.28Å; P447-L449 PolarHBondContact O-N 3.01Å; P447-Y450 WeakPolarHBondContact O-CB 3.34Å; P447-Y450 PolarHBondContact O-N 3.29Å; P447-Y450 VanDerWaalsContact O-N 3.13Å; P447-G451 PolarHBondContact O-N 3.32Å
448	S	92	Very high	91.6	Very high	27 Å²	27	18 Å²	18	19%	0.189	12%	0.117	C	C	.	.	H	α-helix	trans	-62.3	-35.3	175.2	-66.2	0	0	0	0	112.7	G310 D314 S446 Y450 G451 L452	G310-S448 PolarHBondContact O-N 3.11Å; D314-S448 WeakPolarHBondContact OD2-CB 3.15Å; D314-S448 PolarHBondContact OD2-N 3.02Å; D314-S448 PolarHBondContact OD2-OG 3.44Å; S446-S448 VanDerWaalsContact C-N 3.26Å; S446-S448 PolarHBondContact O-N 3.17Å; S448-Y450 VanDerWaalsContact C-N 3.3Å; S448-Y450 PolarHBondContact O-N 3.22Å; S448-G451 PolarHBondContact O-N 3.01Å; S448-L452 WeakPolarHBondContact O-CB 3.25Å; S448-L452 PolarHBondContact O-N 3.18Å
449	L	93.9	Very high	91.4	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-62.4	-40.6	175	176.9	71.7	0	0	0	110.9	L440 S446 P447 G451 L452 A453 P501 W502 V504 L505	L440-L449 HydrophobicContact CD1-CD2 4.34Å; S446-L449 VanDerWaalsContact O-CB 3.23Å; S446-L449 WeakPolarHBondContact O-CB 3.23Å; S446-L449 PolarHBondContact O-N 3.35Å; P447-L449 VanDerWaalsContact C-N 3.28Å; P447-L449 PolarHBondContact O-N 3.01Å; L449-G451 VanDerWaalsContact C-N 3.33Å; L449-L452 PolarHBondContact O-N 3.27Å; L449-A453 VanDerWaalsContact O-CB 3.28Å; L449-A453 WeakPolarHBondContact O-CB 3.42Å; L449-A453 PolarHBondContact O-N 2.89Å; L449-P501 HydrophobicContact CD2-CB 3.63Å; L449-P501 HydrophobicContact CD2-CG 4.39Å; L449-P501 WeakPolarHBondContact CD2-O 3.44Å; L449-W502 HydrophobicContact CD1-CD2 3.84Å; L449-W502 HydrophobicContact CD1-CE3 3.62Å; L449-W502 HydrophobicContact CD1-CG 4.31Å; L449-W502 HydrophobicContact CD1-CZ3 4.02Å; L449-V504 HydrophobicContact CD1-CG1 4.2Å; L449-V504 HydrophobicContact CD2-CG1 4.33Å; L449-V504 HydrophobicContact CG-CG1 4.36Å; L449-L505 HydrophobicContact CD1-CD1 4.01Å; L449-L505 HydrophobicContact CD1-CD2 3.74Å; L449-L505 HydrophobicContact CD1-CG 3.85Å
450	Y	93.8	Very high	91.3	Very high	2 Å²	2	22.5 Å²	22.5	1%	0.008	15%	0.145	C	C	.	.	H	α-helix	trans	-65.4	-41	178.1	-49	-19.8	0	0	0	111	L84 I87 F437 L440 Q441 G445 S446 P447 S448 S454	L84-Y450 HydrophobicContact CD2-CD2 3.77Å; L84-Y450 HydrophobicContact CD2-CE2 4.5Å; I87-Y450 HydrophobicContact CD1-CD2 3.96Å; I87-Y450 HydrophobicContact CD1-CE2 3.51Å; F437-Y450 HydrophobicContact CB-CD1 4.33Å; F437-Y450 HydrophobicContact CB-CD2 4.19Å; F437-Y450 HydrophobicContact CB-CE2 4.31Å; F437-Y450 HydrophobicContact CB-CG 4.21Å; F437-Y450 AromaticContact CD1-CD1 3.88Å; F437-Y450 HydrophobicContact CD1-CD1 3.88Å; F437-Y450 AromaticContact CD1-CG 3.96Å; F437-Y450 HydrophobicContact CD1-CG 3.96Å; F437-Y450 HydrophobicContact CD2-CD2 4.29Å; F437-Y450 HydrophobicContact CD2-CG 4.09Å; F437-Y450 HydrophobicContact CE1-CD1 4.36Å; F437-Y450 HydrophobicContact CE1-CG 4.3Å; F437-Y450 HydrophobicContact CE2-CG 4.42Å; F437-Y450 HydrophobicContact CG-CD1 4.12Å; F437-Y450 HydrophobicContact CG-CD2 4.2Å; F437-Y450 AromaticContact CG-CG 3.86Å; F437-Y450 HydrophobicContact CG-CG 3.86Å; L440-Y450 HydrophobicContact CB-CD1 4.32Å; L440-Y450 HydrophobicContact CB-CE1 3.63Å; L440-Y450 HydrophobicContact CD1-CD1 4.02Å; L440-Y450 HydrophobicContact CD1-CE1 4.16Å; Q441-Y450 WeakPolarHBondContact CA-OH 3.47Å; Q441-Y450 WeakPolarHBondContact CB-OH 3.46Å; Q441-Y450 PolarHBondContact N-OH 3.08Å; G445-Y450 PolarHBondContact O-OH 2.79Å; S446-Y450 WeakPolarHBondContact O-CD1 3.39Å; S446-Y450 WeakPolarHBondContact O-CE1 3.26Å; S446-Y450 PolarHBondContact O-N 2.99Å; P447-Y450 WeakPolarHBondContact O-CB 3.34Å; P447-Y450 PolarHBondContact O-N 3.29Å; P447-Y450 VanDerWaalsContact O-N 3.13Å; S448-Y450 VanDerWaalsContact C-N 3.3Å; S448-Y450 PolarHBondContact O-N 3.22Å; Y450-S454 WeakPolarHBondContact O-CB 3.26Å; Y450-S454 PolarHBondContact O-N 3.47Å
451	G	93.8	Very high	90.9	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-56.7	-51.3	172.1	0	0	0	0	0	112.1	M306 P447 S448 L449 S454 V455	M306-G451 WeakPolarHBondContact O-CA 3.35Å; P447-G451 PolarHBondContact O-N 3.32Å; S448-G451 PolarHBondContact O-N 3.01Å; L449-G451 VanDerWaalsContact C-N 3.33Å; G451-S454 WeakPolarHBondContact O-CB 3.4Å; G451-S454 PolarHBondContact O-N 2.66Å; G451-V455 PolarHBondContact O-N 3.19Å; G451-V455 VanDerWaalsContact O-N 3.13Å
452	L	94.5	Very high	90.5	Very high	56 Å²	56	24.7 Å²	24.7	29%	0.293	16%	0.156	S	C	.	.	H	α-helix	trans	-65.3	-42.2	-180	-175.9	58.9	0	0	0	112.5	F307 S448 L449 S454 V455 I456 W502 L505	F307-L452 HydrophobicContact CE2-CB 4.45Å; F307-L452 HydrophobicContact CE2-CD1 4.38Å; S448-L452 WeakPolarHBondContact O-CB 3.25Å; S448-L452 PolarHBondContact O-N 3.18Å; L449-L452 PolarHBondContact O-N 3.27Å; L452-S454 VanDerWaalsContact C-N 3.26Å; L452-S454 PolarHBondContact O-N 3.03Å; L452-V455 PolarHBondContact O-N 3.11Å; L452-I456 HydrophobicContact CG-CD1 4.37Å; L452-I456 PolarHBondContact O-N 3.36Å; L452-W502 HydrophobicContact CD2-CZ3 4.13Å; L452-L505 HydrophobicContact CB-CD2 4.33Å; L452-L505 HydrophobicContact CD2-CD1 3.6Å; L452-L505 HydrophobicContact CD2-CD2 4.24Å; L452-L505 HydrophobicContact CG-CD1 4.25Å; L452-L505 HydrophobicContact CG-CD2 4.03Å
453	A	93.2	Very high	90.4	Very high	0 Å²	0	24.5 Å²	24.5	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-57.7	-41.1	173.5	0	0	0	0	0	111.2	F437 L449 I456 N457 L505 E508	F437-A453 HydrophobicContact CE1-CB 4.38Å; L449-A453 VanDerWaalsContact O-CB 3.28Å; L449-A453 WeakPolarHBondContact O-CB 3.42Å; L449-A453 PolarHBondContact O-N 2.89Å; A453-I456 PolarHBondContact O-N 2.91Å; A453-N457 WeakPolarHBondContact O-CB 3.45Å; A453-N457 PolarHBondContact O-N 3.49Å; A453-N457 PolarHBondContact O-ND2 2.96Å; A453-L505 HydrophobicContact CB-CD2 4.02Å; A453-E508 HydrophobicContact CB-CG 4.07Å
454	S	91	Very high	90.2	Very high	6 Å²	6	24.1 Å²	24.1	4%	0.042	16%	0.162	C	C	.	.	H	α-helix	trans	-63.7	-41.5	176.7	-163.7	0	0	0	0	112.8	M306 Y450 G451 L452 N457 H458	M306-S454 VanDerWaalsContact CG-CB 3.41Å; M306-S454 WeakPolarHBondContact CG-OG 3.23Å; Y450-S454 WeakPolarHBondContact O-CB 3.26Å; Y450-S454 PolarHBondContact O-N 3.47Å; G451-S454 WeakPolarHBondContact O-CB 3.4Å; G451-S454 PolarHBondContact O-N 2.66Å; L452-S454 VanDerWaalsContact C-N 3.26Å; L452-S454 PolarHBondContact O-N 3.03Å; S454-N457 WeakPolarHBondContact O-CB 3.32Å; S454-N457 PolarHBondContact O-N 2.99Å; S454-H458 PolarHBondContact O-N 3.48Å; S454-H458 VanDerWaalsContact O-N 3.13Å; S454-H458 PolarHBondContact O-ND1 3.18Å
455	V	92.2	Very high	89.8	Confident	44 Å²	44	23.7 Å²	23.7	27%	0.267	14%	0.142	S	C	.	.	H	α-helix	trans	-61.9	-48.4	176.2	173.8	0	0	0	0	110.9	G303 F307 G451 L452 N457 H458 V459	G303-V455 WeakPolarHBondContact O-CG2 3.34Å; F307-V455 HydrophobicContact CB-CG2 3.68Å; F307-V455 HydrophobicContact CD2-CG2 4.12Å; F307-V455 HydrophobicContact CG-CG2 4.04Å; G451-V455 PolarHBondContact O-N 3.19Å; G451-V455 VanDerWaalsContact O-N 3.13Å; L452-V455 PolarHBondContact O-N 3.11Å; V455-N457 VanDerWaalsContact C-N 3.27Å; V455-N457 PolarHBondContact O-N 3.41Å; V455-H458 PolarHBondContact O-N 3.23Å; V455-V459 HydrophobicContact CG1-CG2 4.26Å; V455-V459 WeakPolarHBondContact O-CG2 3.15Å; V455-V459 PolarHBondContact O-N 2.82Å
456	I	93.2	Very high	89.4	Confident	22 Å²	22	30.9 Å²	30.9	11%	0.113	17%	0.171	C	C	.	.	H	α-helix	trans	-59.2	-41.5	179.1	-69	170.8	0	0	0	110.8	L452 A453 V459 S460 L505 E508 F509	L452-I456 HydrophobicContact CG-CD1 4.37Å; L452-I456 PolarHBondContact O-N 3.36Å; A453-I456 PolarHBondContact O-N 2.91Å; I456-V459 PolarHBondContact O-N 3.42Å; I456-S460 VanDerWaalsContact O-CB 3.28Å; I456-S460 WeakPolarHBondContact O-CB 3.47Å; I456-S460 PolarHBondContact O-N 2.99Å; I456-L505 HydrophobicContact CD1-CB 3.83Å; I456-L505 HydrophobicContact CD1-CD2 3.89Å; I456-L505 HydrophobicContact CD1-CG 4.32Å; I456-E508 HydrophobicContact CB-CB 4.23Å; I456-E508 HydrophobicContact CG2-CB 3.7Å; I456-F509 HydrophobicContact CD1-CE2 4.45Å; I456-F509 HydrophobicContact CG1-CZ 4.48Å; I456-F509 HydrophobicContact CG2-CD1 4.02Å; I456-F509 HydrophobicContact CG2-CD2 3.69Å; I456-F509 HydrophobicContact CG2-CE1 4.01Å; I456-F509 HydrophobicContact CG2-CE2 3.68Å; I456-F509 HydrophobicContact CG2-CG 3.86Å; I456-F509 HydrophobicContact CG2-CZ 3.85Å
457	N	89.9	Confident	89.1	Confident	11 Å²	11	35.4 Å²	35.4	6%	0.059	19%	0.187	C	C	.	.	H	α-helix	trans	-58.1	-49.5	176.2	-82.9	-27.8	0	0	0	112.7	A453 S454 V455 S460 E461 E508 Q511	A453-N457 WeakPolarHBondContact O-CB 3.45Å; A453-N457 PolarHBondContact O-N 3.49Å; A453-N457 PolarHBondContact O-ND2 2.96Å; S454-N457 WeakPolarHBondContact O-CB 3.32Å; S454-N457 PolarHBondContact O-N 2.99Å; V455-N457 VanDerWaalsContact C-N 3.27Å; V455-N457 PolarHBondContact O-N 3.41Å; N457-S460 PolarHBondContact O-N 3.38Å; N457-E461 WeakPolarHBondContact O-CG 3.26Å; N457-E461 PolarHBondContact O-N 3.28Å; N457-E508 VanDerWaalsContact CG-OE2 3.23Å; N457-E508 PolarHBondContact ND2-OE2 3.27Å; N457-E508 WeakPolarHBondContact OD1-CA 3.01Å; N457-E508 VanDerWaalsContact OD1-CB 3.26Å; N457-E508 WeakPolarHBondContact OD1-CB 3.41Å; N457-E508 PolarHBondContact OD1-O 3.47Å; N457-E508 PolarHBondContact OD1-OE2 3.49Å; N457-Q511 PolarHBondContact ND2-OE1 2.9Å; N457-Q511 VanDerWaalsContact ND2-OE1 3.13Å; N457-Q511 WeakPolarHBondContact OD1-CB 3.42Å; N457-Q511 VanDerWaalsContact OD1-CD 3.24Å; N457-Q511 PolarHBondContact OD1-OE1 3.27Å
458	H	87.3	Confident	88.5	Confident	24 Å²	24	35.2 Å²	35.2	11%	0.111	19%	0.186	C	C	.	.	H	α-helix	trans	-69.2	-37.8	-179.4	-70.7	79.3	0	0	0	112.2	S299 W302 S454 V455 S460 E461 I462	S299-H458 PolarHBondContact O-CD2 2.99Å; W302-H458 AromaticContact CD1-CE1 3.06Å; W302-H458 AromaticContact CD1-ND1 3.97Å; W302-H458 AromaticContact CD1-NE2 3.38Å; W302-H458 AromaticContact CG-CE1 3.59Å; W302-H458 AromaticContact CG-NE2 3.39Å; W302-H458 AromaticContact NE1-CE1 3.51Å; W302-H458 AromaticContact NE1-NE2 3.97Å; S454-H458 PolarHBondContact O-N 3.48Å; S454-H458 VanDerWaalsContact O-N 3.13Å; S454-H458 PolarHBondContact O-ND1 3.18Å; V455-H458 PolarHBondContact O-N 3.23Å; H458-S460 VanDerWaalsContact C-N 3.33Å; H458-S460 PolarHBondContact O-N 3.04Å; H458-E461 PolarHBondContact O-N 3.48Å; H458-I462 WeakPolarHBondContact O-CG1 3.28Å; H458-I462 PolarHBondContact O-N 3.18Å
459	V	90.1	Very high	87.6	Confident	84 Å²	84	38 Å²	38	51%	0.509	20%	0.195	S	C	.	.	H	α-helix	trans	-61.6	-43.9	173.8	171.2	0	0	0	0	110.6	V455 I456 I462 G463	V455-V459 HydrophobicContact CG1-CG2 4.26Å; V455-V459 WeakPolarHBondContact O-CG2 3.15Å; V455-V459 PolarHBondContact O-N 2.82Å; I456-V459 PolarHBondContact O-N 3.42Å; V459-I462 PolarHBondContact O-N 3.05Å; V459-G463 PolarHBondContact O-N 3.2Å
460	S	90.6	Very high	87.1	Confident	13 Å²	13	44.6 Å²	44.6	9%	0.091	22%	0.22	C	C	.	.	H	α-helix	trans	-63.1	-43	176.3	176	0	0	0	0	112.2	I456 N457 H458 G463 A464 F509 G512	I456-S460 VanDerWaalsContact O-CB 3.28Å; I456-S460 WeakPolarHBondContact O-CB 3.47Å; I456-S460 PolarHBondContact O-N 2.99Å; N457-S460 PolarHBondContact O-N 3.38Å; H458-S460 VanDerWaalsContact C-N 3.33Å; H458-S460 PolarHBondContact O-N 3.04Å; S460-G463 PolarHBondContact O-N 3.19Å; S460-A464 VanDerWaalsContact O-CB 3.29Å; S460-A464 WeakPolarHBondContact O-CB 3.49Å; S460-A464 PolarHBondContact O-N 3.26Å; S460-F509 PolarHBondContact OG-O 3.41Å; S460-G512 VanDerWaalsContact OG-CA 3.25Å; S460-G512 WeakPolarHBondContact OG-CA 3.27Å; S460-G512 PolarHBondContact OG-N 3.37Å
461	E	85	Confident	86.5	Confident	19 Å²	19	46.8 Å²	46.8	9%	0.089	23%	0.231	C	C	.	.	H	α-helix	trans	-60.8	-46.9	176.2	-75.5	-179.9	179.2	0	0	112.2	N457 H458 G463 A464 Y465 Q511 H515 A516	N457-E461 WeakPolarHBondContact O-CG 3.26Å; N457-E461 PolarHBondContact O-N 3.28Å; H458-E461 PolarHBondContact O-N 3.48Å; E461-G463 VanDerWaalsContact C-N 3.35Å; E461-G463 PolarHBondContact O-N 3.26Å; E461-A464 PolarHBondContact O-N 3.01Å; E461-Y465 WeakPolarHBondContact O-CD2 3.02Å; E461-Y465 PolarHBondContact O-N 3.49Å; E461-Q511 HydrophobicContact CG-CG 4.46Å; E461-Q511 PolarHBondContact OE1-NE2 3.3Å; E461-H515 IonicContact OE1-CE1 2.91Å; E461-H515 IonicContact OE1-CG 3.92Å; E461-H515 IonicContact OE1-ND1 2.66Å; E461-H515 PolarHBondContact OE1-ND1 3.4Å; E461-A516 HydrophobicContact CB-CB 4.2Å; E461-A516 HydrophobicContact CG-CB 4.21Å
462	I	84.2	Confident	85.9	Confident	48 Å²	48	47.4 Å²	47.4	25%	0.246	23%	0.234	C	C	.	.	H	α-helix	trans	-57.9	-50.1	176.5	-66.8	168.4	0	0	0	109.9	L296 H458 V459 A464 Y465 F466	L296-I462 HydrophobicContact CD1-CB 4.48Å; L296-I462 HydrophobicContact CD1-CD1 3.74Å; L296-I462 HydrophobicContact CD1-CG1 3.58Å; L296-I462 HydrophobicContact CD1-CG2 4.17Å; H458-I462 WeakPolarHBondContact O-CG1 3.28Å; H458-I462 PolarHBondContact O-N 3.18Å; V459-I462 PolarHBondContact O-N 3.05Å; I462-A464 PolarHBondContact O-N 2.97Å; I462-Y465 PolarHBondContact O-N 3.19Å; I462-F466 HydrophobicContact CG2-CD2 4.12Å; I462-F466 HydrophobicContact CG2-CE2 3.74Å; I462-F466 WeakPolarHBondContact O-CD2 3.13Å; I462-F466 PolarHBondContact O-N 2.87Å
463	G	86.4	Confident	85.2	Confident	26 Å²	26	47.7 Å²	47.7	27%	0.268	24%	0.236	S	C	.	.	H	α-helix	trans	-57.1	-48.8	176.8	0	0	0	0	0	112.2	V459 S460 E461 Y465 F466 F467	V459-G463 PolarHBondContact O-N 3.2Å; S460-G463 PolarHBondContact O-N 3.19Å; E461-G463 VanDerWaalsContact C-N 3.35Å; E461-G463 PolarHBondContact O-N 3.26Å; G463-Y465 VanDerWaalsContact C-N 3.31Å; G463-Y465 PolarHBondContact O-N 3.03Å; G463-F466 PolarHBondContact O-N 3.18Å; G463-F466 VanDerWaalsContact O-N 3.16Å; G463-F467 WeakPolarHBondContact O-CD2 3.2Å; G463-F467 PolarHBondContact O-N 3.4Å
464	A	86	Confident	84.9	Confident	16 Å²	16	55.6 Å²	55.6	13%	0.132	27%	0.271	C	S	.	.	H	α-helix	trans	-61.2	-36.8	179.8	0	0	0	0	0	112.9	S460 E461 I462 F467 S468 G512 A516	S460-A464 VanDerWaalsContact O-CB 3.29Å; S460-A464 WeakPolarHBondContact O-CB 3.49Å; S460-A464 PolarHBondContact O-N 3.26Å; E461-A464 PolarHBondContact O-N 3.01Å; I462-A464 PolarHBondContact O-N 2.97Å; A464-F467 CarbonylContact O-C 3.23Å; A464-F467 PolarHBondContact O-N 3.42Å; A464-S468 WeakPolarHBondContact O-CA 3.33Å; A464-S468 WeakPolarHBondContact O-CB 3.3Å; A464-S468 PolarHBondContact O-N 2.99Å; A464-G512 WeakPolarHBondContact CB-O 3.09Å; A464-A516 HydrophobicContact CB-CB 3.98Å
465	Y	77.1	Confident	84.7	Confident	52 Å²	52	57.4 Å²	57.4	20%	0.204	28%	0.279	C	S	.	.	H	α-helix	trans	-62	-42.3	174.5	-78.8	-56.2	0	0	0	112.7	E461 I462 G463 F467 S468 A516 H614	E461-Y465 WeakPolarHBondContact O-CD2 3.02Å; E461-Y465 PolarHBondContact O-N 3.49Å; I462-Y465 PolarHBondContact O-N 3.19Å; G463-Y465 VanDerWaalsContact C-N 3.31Å; G463-Y465 PolarHBondContact O-N 3.03Å; Y465-F467 PolarHBondContact O-N 2.89Å; Y465-S468 PolarHBondContact O-N 3.5Å; Y465-S468 PolarHBondContact O-OG 3.44Å; Y465-A516 HydrophobicContact CD1-CB 4.12Å; Y465-A516 HydrophobicContact CD2-CB 3.95Å; Y465-A516 HydrophobicContact CE1-CB 3.85Å; Y465-A516 HydrophobicContact CE2-CB 3.67Å; Y465-A516 HydrophobicContact CG-CB 4.17Å; Y465-H614 AromaticContact CE1-CD2 3.32Å; Y465-H614 WeakPolarHBondContact CE1-CD2 3.39Å; Y465-H614 AromaticContact CE1-NE2 3.37Å; Y465-H614 WeakPolarHBondContact CE1-NE2 3.23Å; Y465-H614 AromaticContact CZ-CD2 3.88Å; Y465-H614 AromaticContact CZ-NE2 3.54Å; Y465-H614 PolarHBondContact OH-CE1 3.21Å; Y465-H614 PolarHBondContact OH-NE2 2.75Å; Y465-H614 VanDerWaalsContact OH-NE2 3.13Å
466	F	80.7	Confident	84.1	Confident	157 Å²	157	56.1 Å²	56.1	69%	0.689	28%	0.275	S	S	*	.	H	α-helix	trans	-61.1	-33.4	175.2	-78.4	-74.7	0	0	0	113	I462 G463	I462-F466 HydrophobicContact CG2-CD2 4.12Å; I462-F466 HydrophobicContact CG2-CE2 3.74Å; I462-F466 WeakPolarHBondContact O-CD2 3.13Å; I462-F466 PolarHBondContact O-N 2.87Å; G463-F466 PolarHBondContact O-N 3.18Å; G463-F466 VanDerWaalsContact O-N 3.16Å
467	F	84.8	Confident	83.7	Confident	127 Å²	127	56.8 Å²	56.8	56%	0.557	28%	0.278	S	S	*	.	H	α-helix	trans	-91.4	-13.9	179.7	-64.8	-68.9	0	0	0	114.1	G463 A464 Y465 F469 R470 L471	G463-F467 WeakPolarHBondContact O-CD2 3.2Å; G463-F467 PolarHBondContact O-N 3.4Å; A464-F467 CarbonylContact O-C 3.23Å; A464-F467 PolarHBondContact O-N 3.42Å; Y465-F467 PolarHBondContact O-N 2.89Å; F467-F469 PolarHBondContact O-N 3.13Å; F467-R470 PolarHBondContact O-N 3.37Å; F467-L471 WeakPolarHBondContact O-CB 3.38Å; F467-L471 PolarHBondContact O-N 3.03Å
468	S	77.9	Confident	83.5	Confident	6 Å²	6	57.8 Å²	57.8	4%	0.042	28%	0.284	C	S	.	.	H	α-helix	trans	-57.8	-46.7	-172.1	64.6	0	0	0	0	113.1	A464 Y465 R470 L471 I472	A464-S468 WeakPolarHBondContact O-CA 3.33Å; A464-S468 WeakPolarHBondContact O-CB 3.3Å; A464-S468 PolarHBondContact O-N 2.99Å; Y465-S468 PolarHBondContact O-N 3.5Å; Y465-S468 PolarHBondContact O-OG 3.44Å; S468-R470 PolarHBondContact O-N 3.19Å; S468-L471 PolarHBondContact O-N 2.91Å; S468-I472 WeakPolarHBondContact O-CB 3.24Å; S468-I472 WeakPolarHBondContact O-CD1 3.36Å; S468-I472 WeakPolarHBondContact O-CG1 3.16Å; S468-I472 PolarHBondContact O-N 2.82Å
469	F	74.7	Confident	83.7	Confident	84 Å²	84	61.8 Å²	61.8	37%	0.368	30%	0.301	S	S	.	.	H	α-helix	trans	-59.7	-46.1	178	179.7	-102.6	0	0	0	112.3	F467 L471 I472 N473 M618	F467-F469 PolarHBondContact O-N 3.13Å; F469-L471 VanDerWaalsContact C-N 3.32Å; F469-L471 PolarHBondContact O-N 3.15Å; F469-I472 PolarHBondContact O-N 3.26Å; F469-N473 WeakPolarHBondContact CE1-ND2 3.45Å; F469-N473 VanDerWaalsContact CE2-ND2 3.33Å; F469-N473 WeakPolarHBondContact CE2-ND2 3.35Å; F469-N473 WeakPolarHBondContact CZ-ND2 3.38Å; F469-N473 WeakPolarHBondContact O-CB 3.36Å; F469-N473 PolarHBondContact O-N 3.46Å; F469-N473 PolarHBondContact O-ND2 3.42Å; F469-M618 HydrophobicContact CD2-SD 3.79Å; F469-M618 HydrophobicContact CE2-CE 4.23Å; F469-M618 HydrophobicContact CE2-SD 3.64Å
470	R	81.8	Confident	83.7	Confident	139 Å²	139	57.8 Å²	57.8	53%	0.525	28%	0.277	S	S	.	.	H	α-helix	trans	-63.3	-40.1	176.7	-72.2	-171.9	176.7	152.9	3.9	111.8	F467 S468 K474 Y648	F467-R470 PolarHBondContact O-N 3.37Å; S468-R470 PolarHBondContact O-N 3.19Å; R470-K474 VanDerWaalsContact O-CB 3.25Å; R470-K474 WeakPolarHBondContact O-CB 3.41Å; R470-K474 PolarHBondContact O-N 2.96Å; R470-K474 VanDerWaalsContact O-N 3.14Å; R470-Y648 PolarHBondContact NH2-OH 2.72Å
471	L	81.9	Confident	83.7	Confident	49 Å²	49	57.2 Å²	57.2	26%	0.257	27%	0.273	S	S	.	.	H	α-helix	trans	-66	-50.1	178.6	-174.9	64.5	0	0	0	110.8	F467 S468 F469 N473 K474 I475 V480 L513 A517	F467-L471 WeakPolarHBondContact O-CB 3.38Å; F467-L471 PolarHBondContact O-N 3.03Å; S468-L471 PolarHBondContact O-N 2.91Å; F469-L471 VanDerWaalsContact C-N 3.32Å; F469-L471 PolarHBondContact O-N 3.15Å; L471-N473 PolarHBondContact O-N 3.45Å; L471-K474 PolarHBondContact O-N 2.86Å; L471-I475 HydrophobicContact CD1-CD1 3.88Å; L471-I475 HydrophobicContact CD1-CG1 4.19Å; L471-I475 HydrophobicContact CG-CD1 4.25Å; L471-I475 HydrophobicContact CG-CG1 4.41Å; L471-I475 VanDerWaalsContact O-CG1 3.29Å; L471-I475 WeakPolarHBondContact O-CG1 3.34Å; L471-I475 PolarHBondContact O-N 3.43Å; L471-I475 VanDerWaalsContact O-N 3.07Å; L471-V480 HydrophobicContact CD2-CG1 4.38Å; L471-V480 HydrophobicContact CD2-CG2 4.36Å; L471-V480 HydrophobicContact CG-CG2 4.09Å; L471-L513 HydrophobicContact CD2-CD1 4.01Å; L471-A517 HydrophobicContact CD2-CB 4.26Å
472	I	80.8	Confident	84.1	Confident	12 Å²	12	58.3 Å²	58.3	6%	0.062	28%	0.277	C	S	.	.	H	α-helix	trans	-58.7	-46.1	179.5	-68	162.5	0	0	0	110.9	S468 F469 K474 G476 H477 V480 A520 A521	S468-I472 WeakPolarHBondContact O-CB 3.24Å; S468-I472 WeakPolarHBondContact O-CD1 3.36Å; S468-I472 WeakPolarHBondContact O-CG1 3.16Å; S468-I472 PolarHBondContact O-N 2.82Å; F469-I472 PolarHBondContact O-N 3.26Å; I472-K474 VanDerWaalsContact C-N 3.31Å; I472-K474 PolarHBondContact O-N 2.8Å; I472-G476 WeakPolarHBondContact O-CA 3.43Å; I472-G476 PolarHBondContact O-N 3.49Å; I472-H477 WeakPolarHBondContact CG2-CE1 3.39Å; I472-V480 HydrophobicContact CG1-CG2 4.09Å; I472-A520 HydrophobicContact CD1-CB 4.21Å; I472-A521 HydrophobicContact CD1-CB 4.09Å; I472-A521 HydrophobicContact CG1-CB 4.01Å
473	N	80	Confident	84.6	Confident	63 Å²	63	58.5 Å²	58.5	34%	0.337	28%	0.28	S	S	.	.	H	α-helix	trans	-69.5	-27.2	-179.8	-69.7	-14	0	0	0	113.6	F469 L471	F469-N473 WeakPolarHBondContact CE1-ND2 3.45Å; F469-N473 VanDerWaalsContact CE2-ND2 3.33Å; F469-N473 WeakPolarHBondContact CE2-ND2 3.35Å; F469-N473 WeakPolarHBondContact CZ-ND2 3.38Å; F469-N473 WeakPolarHBondContact O-CB 3.36Å; F469-N473 PolarHBondContact O-N 3.46Å; F469-N473 PolarHBondContact O-ND2 3.42Å; L471-N473 PolarHBondContact O-N 3.45Å
474	K	87.6	Confident	84.9	Confident	166 Å²	166	57.2 Å²	57.2	72%	0.722	27%	0.267	S	S	*	.	H	α-helix	trans	-82.4	-38.9	-178.2	-173.8	174.9	-178.7	177.6	0	113.4	R470 L471 I472	R470-K474 VanDerWaalsContact O-CB 3.25Å; R470-K474 WeakPolarHBondContact O-CB 3.41Å; R470-K474 PolarHBondContact O-N 2.96Å; R470-K474 VanDerWaalsContact O-N 3.14Å; L471-K474 PolarHBondContact O-N 2.86Å; I472-K474 VanDerWaalsContact C-N 3.31Å; I472-K474 PolarHBondContact O-N 2.8Å
475	I	87.4	Confident	85.3	Confident	43 Å²	43	56.5 Å²	56.5	22%	0.221	26%	0.261	C	S	.	.	H	α-helix	trans	-116.1	-14.9	-175	64.8	166.7	0	0	0	114.1	L471 K479 V480 V483	L471-I475 HydrophobicContact CD1-CD1 3.88Å; L471-I475 HydrophobicContact CD1-CG1 4.19Å; L471-I475 HydrophobicContact CG-CD1 4.25Å; L471-I475 HydrophobicContact CG-CG1 4.41Å; L471-I475 VanDerWaalsContact O-CG1 3.29Å; L471-I475 WeakPolarHBondContact O-CG1 3.34Å; L471-I475 PolarHBondContact O-N 3.43Å; L471-I475 VanDerWaalsContact O-N 3.07Å; I475-K479 HydrophobicContact CB-CB 4.11Å; I475-K479 HydrophobicContact CB-CD 4.4Å; I475-K479 HydrophobicContact CD1-CB 4.07Å; I475-K479 HydrophobicContact CG1-CB 4.2Å; I475-K479 WeakPolarHBondContact O-CB 3.03Å; I475-K479 WeakPolarHBondContact O-CD 3.39Å; I475-K479 VanDerWaalsContact O-CG 3.28Å; I475-K479 WeakPolarHBondContact O-CG 3.24Å; I475-V480 HydrophobicContact CD1-CG2 3.85Å; I475-V480 HydrophobicContact CG1-CG2 3.83Å; I475-V483 HydrophobicContact CD1-CG2 4.13Å
476	G	79.5	Confident	86.2	Confident	18 Å²	18	58.9 Å²	58.9	19%	0.186	28%	0.277	C	S	.	.			trans	84	155.8	-176.7	0	0	0	0	0	113.7	I472 T478 K479 V480	I472-G476 WeakPolarHBondContact O-CA 3.43Å; I472-G476 PolarHBondContact O-N 3.49Å; G476-T478 PolarHBondContact O-N 3.49Å; G476-K479 PolarHBondContact O-N 2.89Å; G476-V480 WeakPolarHBondContact O-CG2 3.43Å; G476-V480 PolarHBondContact O-N 3.26Å; G476-V480 VanDerWaalsContact O-N 3.12Å
477	H	83.4	Confident	86.8	Confident	35 Å²	35	52.2 Å²	52.2	16%	0.162	25%	0.251	C	S	.	.	H	α-helix	trans	-58	-46.3	-172.1	-55.8	52.8	0	0	0	113.1	I472 K479 V480 L481 A521 S524 Y525	I472-H477 WeakPolarHBondContact CG2-CE1 3.39Å; H477-K479 VanDerWaalsContact C-N 3.34Å; H477-K479 PolarHBondContact O-N 3.06Å; H477-V480 WeakPolarHBondContact O-CB 3.41Å; H477-V480 PolarHBondContact O-N 2.9Å; H477-L481 WeakPolarHBondContact O-CD1 3.28Å; H477-L481 PolarHBondContact O-N 3.28Å; H477-A521 PolarHBondContact CD2-O 3.24Å; H477-S524 PolarHBondContact NE2-OG 3.31Å; H477-Y525 HydrophobicContact CB-CD2 3.8Å; H477-Y525 HydrophobicContact CB-CG 4.33Å; H477-Y525 PolarHBondContact CD2-N 3.06Å
478	T	87	Confident	87.3	Confident	32 Å²	32	46.6 Å²	46.6	20%	0.196	23%	0.227	C	C	.	.	H	α-helix	trans	-62.4	-39.9	180	-48.1	0	0	0	0	112.1	G476 L481 Y482 F585	G476-T478 PolarHBondContact O-N 3.49Å; T478-L481 WeakPolarHBondContact O-CB 3.28Å; T478-L481 PolarHBondContact O-N 2.89Å; T478-Y482 HydrophobicContact CG2-CE1 4.26Å; T478-Y482 HydrophobicContact CG2-CE2 4.25Å; T478-Y482 PolarHBondContact O-N 3.23Å; T478-F585 HydrophobicContact CG2-CE1 3.86Å; T478-F585 HydrophobicContact CG2-CZ 3.86Å
479	K	89.9	Confident	88.1	Confident	108 Å²	108	47 Å²	47	47%	0.47	23%	0.228	S	C	.	.	H	α-helix	trans	-71.7	-31.3	179.1	-58.3	-169.9	-159.1	155.2	0	111.8	I475 G476 H477 L481 Y482 V483	I475-K479 HydrophobicContact CB-CB 4.11Å; I475-K479 HydrophobicContact CB-CD 4.4Å; I475-K479 HydrophobicContact CD1-CB 4.07Å; I475-K479 HydrophobicContact CG1-CB 4.2Å; I475-K479 WeakPolarHBondContact O-CB 3.03Å; I475-K479 WeakPolarHBondContact O-CD 3.39Å; I475-K479 VanDerWaalsContact O-CG 3.28Å; I475-K479 WeakPolarHBondContact O-CG 3.24Å; G476-K479 PolarHBondContact O-N 2.89Å; H477-K479 VanDerWaalsContact C-N 3.34Å; H477-K479 PolarHBondContact O-N 3.06Å; K479-L481 VanDerWaalsContact C-N 3.28Å; K479-L481 PolarHBondContact O-N 3.47Å; K479-Y482 HydrophobicContact CB-CD2 4.32Å; K479-Y482 HydrophobicContact CG-CD2 4.27Å; K479-Y482 HydrophobicContact CG-CE2 4.41Å; K479-Y482 WeakPolarHBondContact O-CB 3.1Å; K479-Y482 PolarHBondContact O-N 3.41Å; K479-V483 WeakPolarHBondContact O-CG2 3.46Å; K479-V483 PolarHBondContact O-N 3.41Å
480	V	90	Very high	89	Confident	1 Å²	1	44.6 Å²	44.6	1%	0.006	23%	0.228	C	C	.	.	H	α-helix	trans	-59.9	-41.2	170.9	178.2	0	0	0	0	110.8	L471 I472 I475 G476 H477 Y482 V483 G484 A521	L471-V480 HydrophobicContact CD2-CG1 4.38Å; L471-V480 HydrophobicContact CD2-CG2 4.36Å; L471-V480 HydrophobicContact CG-CG2 4.09Å; I472-V480 HydrophobicContact CG1-CG2 4.09Å; I475-V480 HydrophobicContact CD1-CG2 3.85Å; I475-V480 HydrophobicContact CG1-CG2 3.83Å; G476-V480 WeakPolarHBondContact O-CG2 3.43Å; G476-V480 PolarHBondContact O-N 3.26Å; G476-V480 VanDerWaalsContact O-N 3.12Å; H477-V480 WeakPolarHBondContact O-CB 3.41Å; H477-V480 PolarHBondContact O-N 2.9Å; V480-Y482 PolarHBondContact O-N 2.85Å; V480-V483 PolarHBondContact O-N 3.48Å; V480-G484 PolarHBondContact O-N 3.15Å; V480-A521 HydrophobicContact CB-CB 3.86Å; V480-A521 HydrophobicContact CG1-CB 3.67Å; V480-A521 HydrophobicContact CG2-CB 4.43Å
481	L	90.8	Very high	89.6	Confident	0 Å²	0	38.5 Å²	38.5	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-63.5	-38.4	174.5	-92.1	67.6	0	0	0	112.5	F418 V421 T422 H477 T478 K479 V483 G484 L485 V518 A521 F585	F418-L481 HydrophobicContact CD2-CD2 3.65Å; F418-L481 HydrophobicContact CE2-CD1 3.8Å; F418-L481 HydrophobicContact CE2-CD2 3.23Å; F418-L481 HydrophobicContact CE2-CG 4.17Å; F418-L481 HydrophobicContact CZ-CD1 4.13Å; F418-L481 HydrophobicContact CZ-CD2 3.78Å; V421-L481 HydrophobicContact CB-CD2 4.3Å; V421-L481 HydrophobicContact CG1-CD2 3.86Å; V421-L481 HydrophobicContact CG1-CG 4.39Å; T422-L481 HydrophobicContact CG2-CD2 4.33Å; H477-L481 WeakPolarHBondContact O-CD1 3.28Å; H477-L481 PolarHBondContact O-N 3.28Å; T478-L481 WeakPolarHBondContact O-CB 3.28Å; T478-L481 PolarHBondContact O-N 2.89Å; K479-L481 VanDerWaalsContact C-N 3.28Å; K479-L481 PolarHBondContact O-N 3.47Å; L481-V483 VanDerWaalsContact C-N 3.35Å; L481-V483 PolarHBondContact O-N 3.23Å; L481-G484 PolarHBondContact O-N 2.86Å; L481-L485 PolarHBondContact O-N 3.15Å; L481-V518 HydrophobicContact CD1-CG1 4.46Å; L481-A521 HydrophobicContact CD1-CB 4.12Å; L481-F585 HydrophobicContact CB-CE1 4.08Å; L481-F585 HydrophobicContact CD2-CE1 4.2Å; L481-F585 HydrophobicContact CD2-CZ 4.28Å
482	Y	94.1	Very high	90.1	Very high	42 Å²	42	36.2 Å²	36.2	17%	0.165	19%	0.193	C	C	.	.	H	α-helix	trans	-59.8	-46	173.4	-61.2	-31.2	0	0	0	112	T478 K479 V480 G484 L485 L486 L582 F585 Y586 N589	T478-Y482 HydrophobicContact CG2-CE1 4.26Å; T478-Y482 HydrophobicContact CG2-CE2 4.25Å; T478-Y482 PolarHBondContact O-N 3.23Å; K479-Y482 HydrophobicContact CB-CD2 4.32Å; K479-Y482 HydrophobicContact CG-CD2 4.27Å; K479-Y482 HydrophobicContact CG-CE2 4.41Å; K479-Y482 WeakPolarHBondContact O-CB 3.1Å; K479-Y482 PolarHBondContact O-N 3.41Å; V480-Y482 PolarHBondContact O-N 2.85Å; Y482-G484 VanDerWaalsContact C-N 3.31Å; Y482-G484 PolarHBondContact O-N 2.69Å; Y482-L485 PolarHBondContact O-N 3.02Å; Y482-L486 WeakPolarHBondContact O-CB 3.38Å; Y482-L486 PolarHBondContact O-N 3.39Å; Y482-L582 HydrophobicContact CD1-CD1 3.65Å; Y482-L582 HydrophobicContact CG-CD1 4.03Å; Y482-F585 AromaticContact CD1-CD1 3.66Å; Y482-F585 HydrophobicContact CD1-CD1 3.66Å; Y482-F585 HydrophobicContact CD1-CE1 4.05Å; Y482-F585 HydrophobicContact CE1-CB 4.49Å; Y482-F585 AromaticContact CE1-CD1 3.26Å; Y482-F585 HydrophobicContact CE1-CD1 3.26Å; Y482-F585 AromaticContact CE1-CE1 3.65Å; Y482-F585 HydrophobicContact CE1-CE1 3.65Å; Y482-F585 HydrophobicContact CE1-CG 4.07Å; Y482-Y586 HydrophobicContact CE2-CD2 4.19Å; Y482-N589 VanDerWaalsContact OH-CB 3.26Å; Y482-N589 WeakPolarHBondContact OH-CB 3.48Å; Y482-N589 PolarHBondContact OH-ND2 2.85Å
483	V	93.8	Very high	90.8	Very high	52 Å²	52	36.9 Å²	36.9	32%	0.315	20%	0.196	S	C	.	.	H	α-helix	trans	-60.9	-43.2	176.8	173.1	0	0	0	0	110.3	I475 K479 V480 L481 L486 A487 L513	I475-V483 HydrophobicContact CD1-CG2 4.13Å; K479-V483 WeakPolarHBondContact O-CG2 3.46Å; K479-V483 PolarHBondContact O-N 3.41Å; V480-V483 PolarHBondContact O-N 3.48Å; L481-V483 VanDerWaalsContact C-N 3.35Å; L481-V483 PolarHBondContact O-N 3.23Å; V483-L486 PolarHBondContact O-N 3.35Å; V483-A487 VanDerWaalsContact O-CB 3.23Å; V483-A487 WeakPolarHBondContact O-CB 3.43Å; V483-A487 PolarHBondContact O-N 3.05Å; V483-L513 HydrophobicContact CG1-CD1 3.97Å; V483-L513 HydrophobicContact CG1-CD2 3.74Å; V483-L513 HydrophobicContact CG1-CG 4.07Å
484	G	93.4	Very high	91.4	Very high	0 Å²	0	36.5 Å²	36.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-61.4	-45	176.5	0	0	0	0	0	113.7	V480 L481 Y482 N488	V480-G484 PolarHBondContact O-N 3.15Å; L481-G484 PolarHBondContact O-N 2.86Å; Y482-G484 VanDerWaalsContact C-N 3.31Å; Y482-G484 PolarHBondContact O-N 2.69Å; G484-N488 PolarHBondContact O-N 3.27Å
485	L	94.9	Very high	91.6	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-63.8	-46.6	175.6	-77	171.9	0	0	0	111.6	V421 M425 L481 Y482 A487 N488 V489 I581 L582	V421-L485 HydrophobicContact CG1-CD1 3.78Å; V421-L485 HydrophobicContact CG1-CD2 4.26Å; V421-L485 HydrophobicContact CG1-CG 4.1Å; V421-L485 HydrophobicContact CG2-CD1 4.49Å; M425-L485 HydrophobicContact CG-CD2 4.03Å; M425-L485 HydrophobicContact SD-CD2 4.32Å; M425-L485 HydrophobicContact SD-CG 4.36Å; L481-L485 PolarHBondContact O-N 3.15Å; Y482-L485 PolarHBondContact O-N 3.02Å; L485-A487 VanDerWaalsContact C-N 3.34Å; L485-A487 PolarHBondContact O-N 3.25Å; L485-N488 WeakPolarHBondContact O-CB 3.28Å; L485-N488 PolarHBondContact O-N 3.34Å; L485-N488 VanDerWaalsContact O-N 3.14Å; L485-V489 WeakPolarHBondContact O-CG2 3.4Å; L485-V489 PolarHBondContact O-N 2.9Å; L485-I581 HydrophobicContact CD1-CG2 4.21Å; L485-I581 HydrophobicContact CD2-CG2 4.38Å; L485-L582 HydrophobicContact CB-CB 4.14Å; L485-L582 HydrophobicContact CB-CD1 4.16Å; L485-L582 HydrophobicContact CD1-CB 4.1Å; L485-L582 HydrophobicContact CD1-CD1 4.18Å
486	L	95.6	Very high	91.9	Very high	103 Å²	103	26.7 Å²	26.7	54%	0.539	15%	0.146	S	C	.	.	H	α-helix	trans	-61.4	-42.6	178.3	-178.2	62.6	0	0	0	111.8	Y482 V483 N488 V489 G490 L582	Y482-L486 WeakPolarHBondContact O-CB 3.38Å; Y482-L486 PolarHBondContact O-N 3.39Å; V483-L486 PolarHBondContact O-N 3.35Å; L486-N488 VanDerWaalsContact C-N 3.3Å; L486-N488 PolarHBondContact O-N 2.92Å; L486-V489 WeakPolarHBondContact O-CB 3.27Å; L486-V489 PolarHBondContact O-N 2.84Å; L486-G490 PolarHBondContact O-N 3.27Å; L486-G490 VanDerWaalsContact O-N 3.15Å; L486-L582 HydrophobicContact CB-CD2 4.1Å; L486-L582 HydrophobicContact CD1-CD2 4.33Å
487	A	94.5	Very high	92.5	Very high	17 Å²	17	33.2 Å²	33.2	14%	0.14	17%	0.165	C	C	.	.	H	α-helix	trans	-63.5	-36.3	175.4	0	0	0	0	0	111.8	V483 L485 G490 R491 I510 L513 T514	V483-A487 VanDerWaalsContact O-CB 3.23Å; V483-A487 WeakPolarHBondContact O-CB 3.43Å; V483-A487 PolarHBondContact O-N 3.05Å; L485-A487 VanDerWaalsContact C-N 3.34Å; L485-A487 PolarHBondContact O-N 3.25Å; A487-G490 PolarHBondContact O-N 3.34Å; A487-R491 WeakPolarHBondContact O-CB 3.2Å; A487-R491 PolarHBondContact O-N 2.53Å; A487-I510 HydrophobicContact CB-CG2 3.8Å; A487-L513 HydrophobicContact CB-CD2 4.27Å; A487-T514 HydrophobicContact CB-CG2 3.41Å; A487-T514 VanDerWaalsContact CB-CG2 3.41Å
488	N	94.1	Very high	92.8	Very high	9 Å²	9	31.9 Å²	31.9	5%	0.048	16%	0.159	C	C	.	.	H	α-helix	trans	-66.2	-36.7	171.9	-86.2	-31.8	0	0	0	113	M425 G484 L485 L486 G490 R491 F492 T514	M425-N488 WeakPolarHBondContact CE-ND2 3.43Å; G484-N488 PolarHBondContact O-N 3.27Å; L485-N488 WeakPolarHBondContact O-CB 3.28Å; L485-N488 PolarHBondContact O-N 3.34Å; L485-N488 VanDerWaalsContact O-N 3.14Å; L486-N488 VanDerWaalsContact C-N 3.3Å; L486-N488 PolarHBondContact O-N 2.92Å; N488-G490 VanDerWaalsContact C-N 3.35Å; N488-G490 PolarHBondContact O-N 3.23Å; N488-R491 PolarHBondContact O-N 3.31Å; N488-F492 WeakPolarHBondContact O-CD2 3.32Å; N488-F492 PolarHBondContact O-N 3.47Å; N488-T514 WeakPolarHBondContact OD1-CB 3.47Å; N488-T514 WeakPolarHBondContact OD1-CG2 3.46Å
489	V	95.6	Very high	92.8	Very high	13 Å²	13	41.1 Å²	41.1	8%	0.079	19%	0.191	C	C	.	.	H	α-helix	trans	-56.4	-52.1	172	178.9	0	0	0	0	109.7	L485 L486 R491 L493 G575 C578 L579	L485-V489 WeakPolarHBondContact O-CG2 3.4Å; L485-V489 PolarHBondContact O-N 2.9Å; L486-V489 WeakPolarHBondContact O-CB 3.27Å; L486-V489 PolarHBondContact O-N 2.84Å; V489-R491 PolarHBondContact O-N 3.33Å; V489-L493 HydrophobicContact CG1-CD1 3.7Å; V489-L493 HydrophobicContact CG1-CG 4.37Å; V489-L493 WeakPolarHBondContact O-CB 3.16Å; V489-L493 VanDerWaalsContact O-CG 3.24Å; V489-L493 WeakPolarHBondContact O-CG 3.11Å; V489-L493 PolarHBondContact O-N 3.35Å; V489-L493 VanDerWaalsContact O-N 3.11Å; V489-G575 WeakPolarHBondContact CG2-O 3.49Å; V489-C578 HydrophobicContact CG2-CB 3.75Å; V489-L579 HydrophobicContact CG1-CB 4.46Å; V489-L579 HydrophobicContact CG2-CB 3.9Å
490	G	93.2	Very high	92.8	Very high	34 Å²	34	39.4 Å²	39.4	35%	0.351	19%	0.187	S	C	.	.	H	α-helix	trans	-58.7	-48.6	177.9	0	0	0	0	0	112.5	L486 A487 N488 Y494	L486-G490 PolarHBondContact O-N 3.27Å; L486-G490 VanDerWaalsContact O-N 3.15Å; A487-G490 PolarHBondContact O-N 3.34Å; N488-G490 VanDerWaalsContact C-N 3.35Å; N488-G490 PolarHBondContact O-N 3.23Å; G490-Y494 WeakPolarHBondContact O-CB 3.26Å; G490-Y494 PolarHBondContact O-N 3.38Å
491	R	93.2	Very high	92.8	Very high	12 Å²	12	39.9 Å²	39.9	5%	0.045	19%	0.189	C	C	.	.	H	α-helix	trans	-57.4	-53.8	-178.8	-176.2	-179.5	-176.5	171.1	8.2	112.2	A487 N488 V489 Y494 I495 E508	A487-R491 WeakPolarHBondContact O-CB 3.2Å; A487-R491 PolarHBondContact O-N 2.53Å; N488-R491 PolarHBondContact O-N 3.31Å; V489-R491 PolarHBondContact O-N 3.33Å; R491-Y494 PolarHBondContact O-N 3.05Å; R491-I495 HydrophobicContact CG-CD1 3.82Å; R491-I495 WeakPolarHBondContact O-CD1 3.47Å; R491-I495 VanDerWaalsContact O-CG1 3.24Å; R491-I495 WeakPolarHBondContact O-CG1 3.35Å; R491-I495 PolarHBondContact O-N 3.05Å; R491-E508 IonicContact CZ-OE2 3.58Å; R491-E508 IonicContact NH2-OE2 3.2Å; R491-E508 PolarHBondContact NH2-OE2 3.04Å
492	F	94.3	Very high	92.9	Very high	1 Å²	1	46 Å²	46	0%	0.004	21%	0.213	C	C	.	.	H	α-helix	trans	-73.8	-36.5	-173.9	-83.2	-94.6	0	0	0	113.2	L431 V432 N488 S496 F571 Y574	L431-F492 HydrophobicContact CB-CE1 4.17Å; L431-F492 HydrophobicContact CB-CZ 4.44Å; L431-F492 HydrophobicContact CD1-CE1 4.28Å; V432-F492 HydrophobicContact CG2-CE1 3.98Å; V432-F492 HydrophobicContact CG2-CE2 4.15Å; V432-F492 HydrophobicContact CG2-CZ 3.52Å; N488-F492 WeakPolarHBondContact O-CD2 3.32Å; N488-F492 PolarHBondContact O-N 3.47Å; F492-S496 WeakPolarHBondContact O-CB 3.49Å; F492-S496 PolarHBondContact O-N 2.9Å; F492-S496 VanDerWaalsContact O-N 3.13Å; F492-F571 WeakPolarHBondContact CB-O 3.31Å; F492-F571 HydrophobicContact CD1-CB 4.13Å; F492-F571 AromaticContact CD1-CD1 3.76Å; F492-F571 HydrophobicContact CD1-CD1 3.76Å; F492-F571 HydrophobicContact CD1-CG 4.21Å; F492-F571 AromaticContact CE1-CD1 3.89Å; F492-F571 HydrophobicContact CE1-CD1 3.89Å; F492-F571 HydrophobicContact CE1-CE1 4.32Å; F492-Y574 HydrophobicContact CB-CD1 4.23Å; F492-Y574 AromaticContact CD1-CD1 3.55Å; F492-Y574 HydrophobicContact CD1-CD1 3.55Å; F492-Y574 HydrophobicContact CD1-CE1 4.31Å; F492-Y574 HydrophobicContact CD1-CG 4.19Å; F492-Y574 AromaticContact CD2-CD1 3.46Å; F492-Y574 HydrophobicContact CD2-CD1 3.46Å; F492-Y574 VanDerWaalsContact CD2-CD1 3.46Å; F492-Y574 AromaticContact CD2-CE1 3.54Å; F492-Y574 HydrophobicContact CD2-CE1 3.54Å; F492-Y574 AromaticContact CE1-CD1 3.57Å; F492-Y574 HydrophobicContact CE1-CD1 3.57Å; F492-Y574 HydrophobicContact CE1-CE1 4.05Å; F492-Y574 HydrophobicContact CE1-CG 4.12Å; F492-Y574 AromaticContact CE2-CD1 3.5Å; F492-Y574 HydrophobicContact CE2-CD1 3.5Å; F492-Y574 VanDerWaalsContact CE2-CD1 3.5Å; F492-Y574 AromaticContact CE2-CE1 3.22Å; F492-Y574 HydrophobicContact CE2-CE1 3.22Å; F492-Y574 AromaticContact CG-CD1 3.47Å; F492-Y574 HydrophobicContact CG-CD1 3.47Å; F492-Y574 VanDerWaalsContact CG-CD1 3.47Å; F492-Y574 HydrophobicContact CG-CE1 4.06Å; F492-Y574 HydrophobicContact CG-CG 4.47Å; F492-Y574 AromaticContact CZ-CD1 3.52Å; F492-Y574 HydrophobicContact CZ-CD1 3.52Å; F492-Y574 AromaticContact CZ-CE1 3.48Å; F492-Y574 HydrophobicContact CZ-CE1 3.48Å; F492-Y574 VanDerWaalsContact CZ-CE1 3.48Å; F492-Y574 HydrophobicContact CZ-CG 4.34Å
493	L	94.5	Very high	92.8	Very high	25 Å²	25	51.2 Å²	51.2	13%	0.131	23%	0.232	C	C	.	.	H	α-helix	trans	-64	-43.9	173.2	-69.5	179.5	0	0	0	110.9	V489 S496 W497 R572 F576	V489-L493 HydrophobicContact CG1-CD1 3.7Å; V489-L493 HydrophobicContact CG1-CG 4.37Å; V489-L493 WeakPolarHBondContact O-CB 3.16Å; V489-L493 VanDerWaalsContact O-CG 3.24Å; V489-L493 WeakPolarHBondContact O-CG 3.11Å; V489-L493 PolarHBondContact O-N 3.35Å; V489-L493 VanDerWaalsContact O-N 3.11Å; L493-S496 WeakPolarHBondContact O-CB 3.27Å; L493-S496 PolarHBondContact O-N 3.13Å; L493-S496 PolarHBondContact O-OG 3.29Å; L493-W497 HydrophobicContact CB-CE3 4.39Å; L493-W497 HydrophobicContact CB-CH2 4.47Å; L493-W497 HydrophobicContact CB-CZ3 4Å; L493-W497 PolarHBondContact O-N 3.17Å; L493-R572 HydrophobicContact CD2-CG 4.46Å; L493-F576 HydrophobicContact CD2-CD2 4.25Å; L493-F576 HydrophobicContact CD2-CE2 3.95Å; L493-F576 HydrophobicContact CD2-CZ 4.23Å
494	Y	92.8	Very high	92.7	Very high	56 Å²	56	48.8 Å²	48.8	22%	0.22	22%	0.217	C	C	.	.	H	α-helix	trans	-60.9	-52.2	177.8	-178.4	-98.7	0	0	0	112.3	G490 R491 S496 W497 L498 W503 F507	G490-Y494 WeakPolarHBondContact O-CB 3.26Å; G490-Y494 PolarHBondContact O-N 3.38Å; R491-Y494 PolarHBondContact O-N 3.05Å; Y494-S496 PolarHBondContact O-N 3.34Å; Y494-W497 PolarHBondContact O-N 2.94Å; Y494-L498 HydrophobicContact CD1-CD1 4.45Å; Y494-L498 HydrophobicContact CD1-CD2 4.23Å; Y494-L498 HydrophobicContact CD1-CG 4.28Å; Y494-L498 HydrophobicContact CE1-CD1 4.23Å; Y494-L498 HydrophobicContact CE1-CD2 3.5Å; Y494-L498 VanDerWaalsContact CE1-CD2 3.5Å; Y494-L498 HydrophobicContact CE1-CG 4.01Å; Y494-L498 PolarHBondContact O-N 3.3Å; Y494-W503 VanDerWaalsContact CE1-O 3.27Å; Y494-W503 WeakPolarHBondContact CE1-O 3.12Å; Y494-W503 WeakPolarHBondContact OH-CB 3.5Å; Y494-W503 PolarHBondContact OH-O 3.27Å; Y494-F507 HydrophobicContact CD1-CB 4.01Å; Y494-F507 AromaticContact CD1-CD1 3.79Å; Y494-F507 HydrophobicContact CD1-CD1 3.79Å; Y494-F507 AromaticContact CD1-CD2 3.28Å; Y494-F507 HydrophobicContact CD1-CD2 3.28Å; Y494-F507 HydrophobicContact CD1-CE1 4.07Å; Y494-F507 AromaticContact CD1-CE2 3.59Å; Y494-F507 HydrophobicContact CD1-CE2 3.59Å; Y494-F507 AromaticContact CD1-CG 3.39Å; Y494-F507 HydrophobicContact CD1-CG 3.39Å; Y494-F507 AromaticContact CD1-CZ 3.97Å; Y494-F507 HydrophobicContact CD1-CZ 3.97Å; Y494-F507 HydrophobicContact CD2-CD2 4.09Å; Y494-F507 AromaticContact CD2-CE1 3.98Å; Y494-F507 HydrophobicContact CD2-CE1 3.98Å; Y494-F507 AromaticContact CD2-CE2 3.46Å; Y494-F507 HydrophobicContact CD2-CE2 3.46Å; Y494-F507 VanDerWaalsContact CD2-CE2 3.46Å; Y494-F507 AromaticContact CD2-CZ 3.39Å; Y494-F507 HydrophobicContact CD2-CZ 3.39Å; Y494-F507 HydrophobicContact CE1-CB 4.19Å; Y494-F507 HydrophobicContact CE1-CD1 4.38Å; Y494-F507 AromaticContact CE1-CD2 3.01Å; Y494-F507 HydrophobicContact CE1-CD2 3.01Å; Y494-F507 AromaticContact CE1-CE2 3.35Å; Y494-F507 HydrophobicContact CE1-CE2 3.35Å; Y494-F507 AromaticContact CE1-CG 3.61Å; Y494-F507 HydrophobicContact CE1-CG 3.61Å; Y494-F507 HydrophobicContact CE1-CZ 4.17Å; Y494-F507 AromaticContact CE2-CD2 3.88Å; Y494-F507 HydrophobicContact CE2-CD2 3.88Å; Y494-F507 AromaticContact CE2-CE2 3.22Å; Y494-F507 HydrophobicContact CE2-CE2 3.22Å; Y494-F507 AromaticContact CE2-CZ 3.63Å; Y494-F507 HydrophobicContact CE2-CZ 3.63Å; Y494-F507 AromaticContact CG-CD1 3.85Å; Y494-F507 HydrophobicContact CG-CD1 3.85Å; Y494-F507 AromaticContact CG-CD2 3.8Å; Y494-F507 HydrophobicContact CG-CD2 3.8Å; Y494-F507 AromaticContact CG-CE1 3.68Å; Y494-F507 HydrophobicContact CG-CE1 3.68Å; Y494-F507 AromaticContact CG-CE2 3.61Å; Y494-F507 HydrophobicContact CG-CE2 3.61Å; Y494-F507 AromaticContact CG-CG 3.91Å; Y494-F507 HydrophobicContact CG-CG 3.91Å; Y494-F507 AromaticContact CG-CZ 3.55Å; Y494-F507 HydrophobicContact CG-CZ 3.55Å; Y494-F507 AromaticContact CZ-CD2 3.32Å; Y494-F507 AromaticContact CZ-CE2 3.12Å; Y494-F507 AromaticContact CZ-CZ 3.99Å
495	I	92.7	Very high	92.7	Very high	2 Å²	2	49.9 Å²	49.9	1%	0.01	22%	0.223	C	C	.	.	H	α-helix	trans	-54.5	-39.6	177.7	-67.8	164.4	0	0	0	110.6	L436 H439 R491 W497 L498 F571	L436-I495 HydrophobicContact CD1-CD1 4.04Å; L436-I495 HydrophobicContact CD1-CG2 4.2Å; H439-I495 PolarHBondContact NE2-O 3.13Å; R491-I495 HydrophobicContact CG-CD1 3.82Å; R491-I495 WeakPolarHBondContact O-CD1 3.47Å; R491-I495 VanDerWaalsContact O-CG1 3.24Å; R491-I495 WeakPolarHBondContact O-CG1 3.35Å; R491-I495 PolarHBondContact O-N 3.05Å; I495-W497 PolarHBondContact O-N 3.43Å; I495-L498 HydrophobicContact CG1-CD1 4.48Å; I495-L498 WeakPolarHBondContact O-CB 3.4Å; I495-L498 PolarHBondContact O-N 3.5Å; I495-F571 HydrophobicContact CG2-CD2 3.61Å; I495-F571 HydrophobicContact CG2-CE2 3.68Å; I495-F571 HydrophobicContact CG2-CG 4.49Å
496	S	93.6	Very high	92.4	Very high	0 Å²	0	53 Å²	53	0%	0	24%	0.243	C	C	.	.	H	α-helix	trans	-66.5	-19.1	179.9	86.2	0	0	0	0	115.5	F492 L493 Y494 R572	F492-S496 WeakPolarHBondContact O-CB 3.49Å; F492-S496 PolarHBondContact O-N 2.9Å; F492-S496 VanDerWaalsContact O-N 3.13Å; L493-S496 WeakPolarHBondContact O-CB 3.27Å; L493-S496 PolarHBondContact O-N 3.13Å; L493-S496 PolarHBondContact O-OG 3.29Å; Y494-S496 PolarHBondContact O-N 3.34Å; S496-R572 PolarHBondContact O-NH2 3.24Å; S496-R572 WeakPolarHBondContact OG-CG 3.36Å; S496-R572 PolarHBondContact OG-NE 3.26Å
497	W	91.5	Very high	91.9	Very high	155 Å²	155	50.6 Å²	50.6	59%	0.587	23%	0.229	S	C	*	.	H	α-helix	trans	-104.4	-3.8	-179.9	-73.5	-45.7	0	0	0	113.5	L493 Y494 I495 R499	L493-W497 HydrophobicContact CB-CE3 4.39Å; L493-W497 HydrophobicContact CB-CH2 4.47Å; L493-W497 HydrophobicContact CB-CZ3 4Å; L493-W497 PolarHBondContact O-N 3.17Å; Y494-W497 PolarHBondContact O-N 2.94Å; I495-W497 PolarHBondContact O-N 3.43Å; W497-R499 PolarHBondContact O-N 2.99Å
498	L	89.9	Confident	91.7	Very high	8 Å²	8	49.9 Å²	49.9	4%	0.042	22%	0.222	C	C	.	.			trans	-57.1	128.6	174.7	-73.8	174.9	0	0	0	110.7	I443 Y494 I495 W503 V504	I443-L498 HydrophobicContact CD1-CB 4.05Å; Y494-L498 HydrophobicContact CD1-CD1 4.45Å; Y494-L498 HydrophobicContact CD1-CD2 4.23Å; Y494-L498 HydrophobicContact CD1-CG 4.28Å; Y494-L498 HydrophobicContact CE1-CD1 4.23Å; Y494-L498 HydrophobicContact CE1-CD2 3.5Å; Y494-L498 VanDerWaalsContact CE1-CD2 3.5Å; Y494-L498 HydrophobicContact CE1-CG 4.01Å; Y494-L498 PolarHBondContact O-N 3.3Å; I495-L498 HydrophobicContact CG1-CD1 4.48Å; I495-L498 WeakPolarHBondContact O-CB 3.4Å; I495-L498 PolarHBondContact O-N 3.5Å; L498-W503 HydrophobicContact CD2-CB 3.52Å; L498-V504 HydrophobicContact CD1-CB 3.92Å; L498-V504 HydrophobicContact CD1-CG2 4.1Å
499	R	86.3	Confident	91.4	Very high	226 Å²	226	55 Å²	55	85%	0.853	24%	0.244	S	C	*	.	S	Bend	trans	-108.2	-43.7	171.5	-66.4	-177.1	-179.3	176.1	-0.3	110.6	W497	W497-R499 PolarHBondContact O-N 2.99Å
500	D	90.1	Very high	91.2	Very high	72 Å²	72	56.7 Å²	56.7	39%	0.385	25%	0.253	S	S	.	.	S	Bend	trans	-97.4	123.8	171.6	172.2	-8.6	0	0	0	108.6	W502 W503	D500-W502 VanDerWaalsContact C-N 3.3Å; D500-W502 PolarHBondContact O-N 3.23Å; D500-W502 PolarHBondContact OD1-N 2.72Å; D500-W503 PolarHBondContact O-N 3.28Å
501	P	90.8	Very high	91.1	Very high	10 Å²	10	56.4 Å²	56.4	7%	0.065	24%	0.242	C	C	.	.	G	3₁₀ helix	trans	-64.8	-27.7	-175.1	27.3	-36.7	0	0	0	113.7	L440 I443 L449 W503 V504	L440-P501 HydrophobicContact CD2-CB 4.37Å; I443-P501 HydrophobicContact CD1-CB 3.98Å; I443-P501 HydrophobicContact CG1-CB 4.04Å; I443-P501 WeakPolarHBondContact O-CD 3.21Å; L449-P501 HydrophobicContact CD2-CB 3.63Å; L449-P501 HydrophobicContact CD2-CG 4.39Å; L449-P501 WeakPolarHBondContact CD2-O 3.44Å; P501-W503 PolarHBondContact O-N 2.95Å; P501-V504 WeakPolarHBondContact O-CB 3.43Å; P501-V504 WeakPolarHBondContact O-CG1 3.41Å; P501-V504 PolarHBondContact O-N 3.42Å; P501-V504 VanDerWaalsContact O-N 3.11Å
502	W	91.8	Very high	90.8	Very high	130 Å²	130	55.8 Å²	55.8	49%	0.492	24%	0.24	S	C	.	.	G	3₁₀ helix	trans	-66.2	-24.2	-176.4	-76.5	90.9	0	0	0	113.3	L449 L452 D500 V504 L505	L449-W502 HydrophobicContact CD1-CD2 3.84Å; L449-W502 HydrophobicContact CD1-CE3 3.62Å; L449-W502 HydrophobicContact CD1-CG 4.31Å; L449-W502 HydrophobicContact CD1-CZ3 4.02Å; L452-W502 HydrophobicContact CD2-CZ3 4.13Å; D500-W502 VanDerWaalsContact C-N 3.3Å; D500-W502 PolarHBondContact O-N 3.23Å; D500-W502 PolarHBondContact OD1-N 2.72Å; W502-V504 PolarHBondContact O-N 2.99Å; W502-V504 VanDerWaalsContact O-N 3.13Å; W502-L505 HydrophobicContact CE3-CD1 3.86Å; W502-L505 HydrophobicContact CZ3-CD1 4.23Å; W502-L505 WeakPolarHBondContact O-CG 3.45Å; W502-L505 PolarHBondContact O-N 3.42Å
503	W	92.4	Very high	90.6	Very high	150 Å²	150	58.5 Å²	58.5	57%	0.568	25%	0.254	S	S	*	.	G	3₁₀ helix	trans	-69.5	-3.2	175.7	-76.7	101.5	0	0	0	113.9	Y494 L498 D500 P501 L505 P506	Y494-W503 VanDerWaalsContact CE1-O 3.27Å; Y494-W503 WeakPolarHBondContact CE1-O 3.12Å; Y494-W503 WeakPolarHBondContact OH-CB 3.5Å; Y494-W503 PolarHBondContact OH-O 3.27Å; L498-W503 HydrophobicContact CD2-CB 3.52Å; D500-W503 PolarHBondContact O-N 3.28Å; P501-W503 PolarHBondContact O-N 2.95Å; W503-L505 VanDerWaalsContact C-N 3.28Å; W503-L505 PolarHBondContact O-N 3.19Å; W503-P506 HydrophobicContact CE3-CG 4.46Å; W503-P506 WeakPolarHBondContact O-CD 3.37Å
504	V	92.4	Very high	90.4	Very high	1 Å²	1	57.7 Å²	57.7	1%	0.006	25%	0.25	C	S	.	.	G	3₁₀ helix	trans	-64.8	-32.7	171.1	76.4	0	0	0	0	112.4	L436 L440 L449 L498 P501 W502 F507 E508	L436-V504 HydrophobicContact CD1-CG2 4.38Å; L440-V504 HydrophobicContact CD1-CB 4.44Å; L440-V504 HydrophobicContact CD1-CG1 3.99Å; L440-V504 HydrophobicContact CD1-CG2 4.3Å; L440-V504 HydrophobicContact CD2-CB 4.09Å; L440-V504 HydrophobicContact CD2-CG1 4.36Å; L440-V504 HydrophobicContact CD2-CG2 4.17Å; L449-V504 HydrophobicContact CD1-CG1 4.2Å; L449-V504 HydrophobicContact CD2-CG1 4.33Å; L449-V504 HydrophobicContact CG-CG1 4.36Å; L498-V504 HydrophobicContact CD1-CB 3.92Å; L498-V504 HydrophobicContact CD1-CG2 4.1Å; P501-V504 WeakPolarHBondContact O-CB 3.43Å; P501-V504 WeakPolarHBondContact O-CG1 3.41Å; P501-V504 PolarHBondContact O-N 3.42Å; P501-V504 VanDerWaalsContact O-N 3.11Å; W502-V504 PolarHBondContact O-N 2.99Å; W502-V504 VanDerWaalsContact O-N 3.13Å; V504-F507 PolarHBondContact O-N 3.47Å; V504-F507 VanDerWaalsContact O-N 3.14Å; V504-E508 HydrophobicContact CG2-CG 4.46Å; V504-E508 WeakPolarHBondContact CG2-OE1 3.41Å; V504-E508 PolarHBondContact O-N 3.47Å
505	L	92.6	Very high	90.1	Very high	24 Å²	24	56.3 Å²	56.3	13%	0.126	25%	0.246	C	C	.	.	H	α-helix	trans	-60.1	-44.2	-167.8	-58.4	174.9	0	0	0	115	L449 L452 A453 I456 W502 W503 F507 E508	L449-L505 HydrophobicContact CD1-CD1 4.01Å; L449-L505 HydrophobicContact CD1-CD2 3.74Å; L449-L505 HydrophobicContact CD1-CG 3.85Å; L452-L505 HydrophobicContact CB-CD2 4.33Å; L452-L505 HydrophobicContact CD2-CD1 3.6Å; L452-L505 HydrophobicContact CD2-CD2 4.24Å; L452-L505 HydrophobicContact CG-CD1 4.25Å; L452-L505 HydrophobicContact CG-CD2 4.03Å; A453-L505 HydrophobicContact CB-CD2 4.02Å; I456-L505 HydrophobicContact CD1-CB 3.83Å; I456-L505 HydrophobicContact CD1-CD2 3.89Å; I456-L505 HydrophobicContact CD1-CG 4.32Å; W502-L505 HydrophobicContact CE3-CD1 3.86Å; W502-L505 HydrophobicContact CZ3-CD1 4.23Å; W502-L505 WeakPolarHBondContact O-CG 3.45Å; W502-L505 PolarHBondContact O-N 3.42Å; W503-L505 VanDerWaalsContact C-N 3.28Å; W503-L505 PolarHBondContact O-N 3.19Å; L505-F507 PolarHBondContact O-N 2.96Å; L505-E508 PolarHBondContact O-N 3.01Å
506	P	88.4	Confident	89.8	Confident	64 Å²	64	56.2 Å²	56.2	42%	0.416	25%	0.245	S	C	.	.	H	α-helix	trans	-61.3	-30.9	178.2	-24.4	36.3	0	0	0	113.5	W503 F509	W503-P506 HydrophobicContact CE3-CG 4.46Å; W503-P506 WeakPolarHBondContact O-CD 3.37Å; P506-F509 PolarHBondContact O-N 2.95Å
507	F	84.7	Confident	89.5	Confident	54 Å²	54	56.3 Å²	56.3	24%	0.237	25%	0.246	C	C	.	.	H	α-helix	trans	-84.4	-18.3	-178.6	-79	-100.5	0	0	0	113	Y494 V504 L505 F509 I510	Y494-F507 HydrophobicContact CD1-CB 4.01Å; Y494-F507 AromaticContact CD1-CD1 3.79Å; Y494-F507 HydrophobicContact CD1-CD1 3.79Å; Y494-F507 AromaticContact CD1-CD2 3.28Å; Y494-F507 HydrophobicContact CD1-CD2 3.28Å; Y494-F507 HydrophobicContact CD1-CE1 4.07Å; Y494-F507 AromaticContact CD1-CE2 3.59Å; Y494-F507 HydrophobicContact CD1-CE2 3.59Å; Y494-F507 AromaticContact CD1-CG 3.39Å; Y494-F507 HydrophobicContact CD1-CG 3.39Å; Y494-F507 AromaticContact CD1-CZ 3.97Å; Y494-F507 HydrophobicContact CD1-CZ 3.97Å; Y494-F507 HydrophobicContact CD2-CD2 4.09Å; Y494-F507 AromaticContact CD2-CE1 3.98Å; Y494-F507 HydrophobicContact CD2-CE1 3.98Å; Y494-F507 AromaticContact CD2-CE2 3.46Å; Y494-F507 HydrophobicContact CD2-CE2 3.46Å; Y494-F507 VanDerWaalsContact CD2-CE2 3.46Å; Y494-F507 AromaticContact CD2-CZ 3.39Å; Y494-F507 HydrophobicContact CD2-CZ 3.39Å; Y494-F507 HydrophobicContact CE1-CB 4.19Å; Y494-F507 HydrophobicContact CE1-CD1 4.38Å; Y494-F507 AromaticContact CE1-CD2 3.01Å; Y494-F507 HydrophobicContact CE1-CD2 3.01Å; Y494-F507 AromaticContact CE1-CE2 3.35Å; Y494-F507 HydrophobicContact CE1-CE2 3.35Å; Y494-F507 AromaticContact CE1-CG 3.61Å; Y494-F507 HydrophobicContact CE1-CG 3.61Å; Y494-F507 HydrophobicContact CE1-CZ 4.17Å; Y494-F507 AromaticContact CE2-CD2 3.88Å; Y494-F507 HydrophobicContact CE2-CD2 3.88Å; Y494-F507 AromaticContact CE2-CE2 3.22Å; Y494-F507 HydrophobicContact CE2-CE2 3.22Å; Y494-F507 AromaticContact CE2-CZ 3.63Å; Y494-F507 HydrophobicContact CE2-CZ 3.63Å; Y494-F507 AromaticContact CG-CD1 3.85Å; Y494-F507 HydrophobicContact CG-CD1 3.85Å; Y494-F507 AromaticContact CG-CD2 3.8Å; Y494-F507 HydrophobicContact CG-CD2 3.8Å; Y494-F507 AromaticContact CG-CE1 3.68Å; Y494-F507 HydrophobicContact CG-CE1 3.68Å; Y494-F507 AromaticContact CG-CE2 3.61Å; Y494-F507 HydrophobicContact CG-CE2 3.61Å; Y494-F507 AromaticContact CG-CG 3.91Å; Y494-F507 HydrophobicContact CG-CG 3.91Å; Y494-F507 AromaticContact CG-CZ 3.55Å; Y494-F507 HydrophobicContact CG-CZ 3.55Å; Y494-F507 AromaticContact CZ-CD2 3.32Å; Y494-F507 AromaticContact CZ-CE2 3.12Å; Y494-F507 AromaticContact CZ-CZ 3.99Å; V504-F507 PolarHBondContact O-N 3.47Å; V504-F507 VanDerWaalsContact O-N 3.14Å; L505-F507 PolarHBondContact O-N 2.96Å; F507-F509 PolarHBondContact O-N 2.88Å; F507-I510 HydrophobicContact CD1-CD1 3.52Å; F507-I510 HydrophobicContact CE1-CD1 3.94Å; F507-I510 HydrophobicContact CG-CD1 4.31Å; F507-I510 VanDerWaalsContact O-CB 3.26Å; F507-I510 WeakPolarHBondContact O-CB 3.09Å; F507-I510 PolarHBondContact O-N 3.38Å
508	E	89.9	Confident	89.4	Confident	1 Å²	1	49.1 Å²	49.1	1%	0.005	22%	0.219	C	C	.	.	H	α-helix	trans	-62.5	-25.7	169.2	-64.8	-55.3	168.3	0	0	111.3	L436 A453 I456 N457 R491 V504 L505 I510 Q511	L436-E508 WeakPolarHBondContact CD2-OE1 3.42Å; A453-E508 HydrophobicContact CB-CG 4.07Å; I456-E508 HydrophobicContact CB-CB 4.23Å; I456-E508 HydrophobicContact CG2-CB 3.7Å; N457-E508 VanDerWaalsContact CG-OE2 3.23Å; N457-E508 PolarHBondContact ND2-OE2 3.27Å; N457-E508 WeakPolarHBondContact OD1-CA 3.01Å; N457-E508 VanDerWaalsContact OD1-CB 3.26Å; N457-E508 WeakPolarHBondContact OD1-CB 3.41Å; N457-E508 PolarHBondContact OD1-O 3.47Å; N457-E508 PolarHBondContact OD1-OE2 3.49Å; R491-E508 IonicContact CZ-OE2 3.58Å; R491-E508 IonicContact NH2-OE2 3.2Å; R491-E508 PolarHBondContact NH2-OE2 3.04Å; V504-E508 HydrophobicContact CG2-CG 4.46Å; V504-E508 WeakPolarHBondContact CG2-OE1 3.41Å; V504-E508 PolarHBondContact O-N 3.47Å; L505-E508 PolarHBondContact O-N 3.01Å; E508-I510 PolarHBondContact O-N 3.49Å; E508-I510 VanDerWaalsContact O-N 3.17Å; E508-Q511 WeakPolarHBondContact O-CB 3.45Å; E508-Q511 PolarHBondContact O-N 3.19Å
509	F	89.6	Confident	89.4	Confident	116 Å²	116	49.5 Å²	49.5	51%	0.509	22%	0.22	S	C	.	.	T	Hydrogen-bonded Turn	trans	-62.1	-22.9	169.5	-76	-76.4	0	0	0	113.7	I456 S460 P506 F507 Q511	I456-F509 HydrophobicContact CD1-CE2 4.45Å; I456-F509 HydrophobicContact CG1-CZ 4.48Å; I456-F509 HydrophobicContact CG2-CD1 4.02Å; I456-F509 HydrophobicContact CG2-CD2 3.69Å; I456-F509 HydrophobicContact CG2-CE1 4.01Å; I456-F509 HydrophobicContact CG2-CE2 3.68Å; I456-F509 HydrophobicContact CG2-CG 3.86Å; I456-F509 HydrophobicContact CG2-CZ 3.85Å; S460-F509 PolarHBondContact OG-O 3.41Å; P506-F509 PolarHBondContact O-N 2.95Å; F507-F509 PolarHBondContact O-N 2.88Å; F509-Q511 PolarHBondContact O-N 3.01Å
510	I	91.4	Very high	89.2	Confident	50 Å²	50	39.3 Å²	39.3	26%	0.256	18%	0.184	S	C	.	.	T	Hydrogen-bonded Turn	trans	-75.2	-16.1	176.4	-58.6	-178.8	0	0	0	111.1	A487 F507 E508 G512 L513 T514	A487-I510 HydrophobicContact CB-CG2 3.8Å; F507-I510 HydrophobicContact CD1-CD1 3.52Å; F507-I510 HydrophobicContact CE1-CD1 3.94Å; F507-I510 HydrophobicContact CG-CD1 4.31Å; F507-I510 VanDerWaalsContact O-CB 3.26Å; F507-I510 WeakPolarHBondContact O-CB 3.09Å; F507-I510 PolarHBondContact O-N 3.38Å; E508-I510 PolarHBondContact O-N 3.49Å; E508-I510 VanDerWaalsContact O-N 3.17Å; I510-G512 PolarHBondContact O-N 2.89Å; I510-L513 PolarHBondContact O-N 3.18Å; I510-T514 HydrophobicContact CG2-CG2 3.8Å; I510-T514 PolarHBondContact O-N 2.97Å; I510-T514 PolarHBondContact O-OG1 3.45Å
511	Q	90	Very high	88.9	Confident	27 Å²	27	35.9 Å²	35.9	13%	0.126	17%	0.166	C	C	.	.	H	α-helix	trans	-56.9	-45.9	178.2	177.8	156	-42.5	0	0	112.4	N457 E461 E508 F509 L513 T514 H515	N457-Q511 PolarHBondContact ND2-OE1 2.9Å; N457-Q511 VanDerWaalsContact ND2-OE1 3.13Å; N457-Q511 WeakPolarHBondContact OD1-CB 3.42Å; N457-Q511 VanDerWaalsContact OD1-CD 3.24Å; N457-Q511 PolarHBondContact OD1-OE1 3.27Å; E461-Q511 HydrophobicContact CG-CG 4.46Å; E461-Q511 PolarHBondContact OE1-NE2 3.3Å; E508-Q511 WeakPolarHBondContact O-CB 3.45Å; E508-Q511 PolarHBondContact O-N 3.19Å; F509-Q511 PolarHBondContact O-N 3.01Å; Q511-L513 PolarHBondContact O-N 3.44Å; Q511-T514 WeakPolarHBondContact CA-OG1 3.2Å; Q511-T514 PolarHBondContact O-N 3.14Å; Q511-T514 VanDerWaalsContact O-N 3.17Å; Q511-T514 PolarHBondContact O-OG1 2.88Å; Q511-T514 VanDerWaalsContact O-OG1 3.11Å; Q511-H515 HydrophobicContact CG-CB 4.19Å; Q511-H515 WeakPolarHBondContact O-CB 3.38Å; Q511-H515 PolarHBondContact O-N 3.15Å
512	G	87.8	Confident	88.7	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-57.1	-37.4	179.2	0	0	0	0	0	113	S460 A464 I510 A516 A517	S460-G512 VanDerWaalsContact OG-CA 3.25Å; S460-G512 WeakPolarHBondContact OG-CA 3.27Å; S460-G512 PolarHBondContact OG-N 3.37Å; A464-G512 WeakPolarHBondContact CB-O 3.09Å; I510-G512 PolarHBondContact O-N 2.89Å; G512-A516 WeakPolarHBondContact O-CA 3.3Å; G512-A516 WeakPolarHBondContact O-CB 3.2Å; G512-A516 PolarHBondContact O-N 3.46Å; G512-A517 PolarHBondContact O-N 2.84Å
513	L	88.9	Confident	88.1	Confident	57 Å²	57	29.4 Å²	29.4	30%	0.298	14%	0.141	S	C	.	.	I	π-helix	trans	-73	-44.2	176.6	-176.6	61.4	0	0	0	112.4	L471 V483 A487 I510 Q511 H515 A517 V518	L471-L513 HydrophobicContact CD2-CD1 4.01Å; V483-L513 HydrophobicContact CG1-CD1 3.97Å; V483-L513 HydrophobicContact CG1-CD2 3.74Å; V483-L513 HydrophobicContact CG1-CG 4.07Å; A487-L513 HydrophobicContact CB-CD2 4.27Å; I510-L513 PolarHBondContact O-N 3.18Å; Q511-L513 PolarHBondContact O-N 3.44Å; L513-H515 VanDerWaalsContact C-N 3.35Å; L513-A517 HydrophobicContact CD1-CB 4.11Å; L513-V518 WeakPolarHBondContact O-CG2 3.43Å
514	T	90.9	Very high	87.3	Confident	9 Å²	9	23 Å²	23	6%	0.055	12%	0.119	C	C	.	.	I	π-helix	trans	-73.9	-26.4	-177.4	50.4	0	0	0	0	113.4	M425 A487 N488 I510 Q511	M425-T514 WeakPolarHBondContact CE-O 3.23Å; A487-T514 HydrophobicContact CB-CG2 3.41Å; A487-T514 VanDerWaalsContact CB-CG2 3.41Å; N488-T514 WeakPolarHBondContact OD1-CB 3.47Å; N488-T514 WeakPolarHBondContact OD1-CG2 3.46Å; I510-T514 HydrophobicContact CG2-CG2 3.8Å; I510-T514 PolarHBondContact O-N 2.97Å; I510-T514 PolarHBondContact O-OG1 3.45Å; Q511-T514 WeakPolarHBondContact CA-OG1 3.2Å; Q511-T514 PolarHBondContact O-N 3.14Å; Q511-T514 VanDerWaalsContact O-N 3.17Å; Q511-T514 PolarHBondContact O-OG1 2.88Å; Q511-T514 VanDerWaalsContact O-OG1 3.11Å
515	H	87.1	Confident	86.8	Confident	26 Å²	26	24.3 Å²	24.3	12%	0.12	12%	0.124	C	C	.	.	I	π-helix	trans	-110.4	-72.3	-175.8	-171.2	-125.7	0	0	0	111.2	E461 Q511 L513 A517 V518 W519 F547	E461-H515 IonicContact OE1-CE1 2.91Å; E461-H515 IonicContact OE1-CG 3.92Å; E461-H515 IonicContact OE1-ND1 2.66Å; E461-H515 PolarHBondContact OE1-ND1 3.4Å; Q511-H515 HydrophobicContact CG-CB 4.19Å; Q511-H515 WeakPolarHBondContact O-CB 3.38Å; Q511-H515 PolarHBondContact O-N 3.15Å; L513-H515 VanDerWaalsContact C-N 3.35Å; H515-A517 PolarHBondContact O-N 3.42Å; H515-V518 PolarHBondContact O-N 2.94Å; H515-W519 WeakPolarHBondContact O-CB 3.4Å; H515-W519 PolarHBondContact O-N 3.09Å; H515-F547 AromaticContact CE1-CZ 3.99Å; H515-F547 AromaticContact NE2-CE1 3.29Å; H515-F547 VanDerWaalsContact NE2-CE1 3.29Å; H515-F547 WeakPolarHBondContact NE2-CE1 3.33Å; H515-F547 AromaticContact NE2-CZ 3.35Å; H515-F547 WeakPolarHBondContact NE2-CZ 2.93Å
516	A	86.1	Confident	86	Confident	0 Å²	0	23.1 Å²	23.1	0%	0	12%	0.118	C	C	.	.	I	π-helix	trans	-63.5	-46.7	-172.2	0	0	0	0	0	113.9	E461 A464 Y465 G512 W519 A520	E461-A516 HydrophobicContact CB-CB 4.2Å; E461-A516 HydrophobicContact CG-CB 4.21Å; A464-A516 HydrophobicContact CB-CB 3.98Å; Y465-A516 HydrophobicContact CD1-CB 4.12Å; Y465-A516 HydrophobicContact CD2-CB 3.95Å; Y465-A516 HydrophobicContact CE1-CB 3.85Å; Y465-A516 HydrophobicContact CE2-CB 3.67Å; Y465-A516 HydrophobicContact CG-CB 4.17Å; G512-A516 WeakPolarHBondContact O-CA 3.3Å; G512-A516 WeakPolarHBondContact O-CB 3.2Å; G512-A516 PolarHBondContact O-N 3.46Å; A516-W519 PolarHBondContact O-N 3.22Å; A516-A520 WeakPolarHBondContact O-CB 3.11Å; A516-A520 PolarHBondContact O-N 3.13Å
517	A	86.7	Confident	85.2	Confident	2 Å²	2	21 Å²	21	2%	0.017	10%	0.104	C	C	.	.	I	π-helix	trans	-68.5	-41.6	-179.2	0	0	0	0	0	112.6	L471 G512 L513 H515 A520 A521	L471-A517 HydrophobicContact CD2-CB 4.26Å; G512-A517 PolarHBondContact O-N 2.84Å; L513-A517 HydrophobicContact CD1-CB 4.11Å; H515-A517 PolarHBondContact O-N 3.42Å; A517-A520 PolarHBondContact O-N 3.42Å; A517-A521 WeakPolarHBondContact O-CB 3.44Å; A517-A521 PolarHBondContact O-N 2.88Å
518	V	90.4	Very high	84.7	Confident	4 Å²	4	23.7 Å²	23.7	2%	0.024	12%	0.12	C	C	.	.	H	α-helix	trans	-64.9	-43.7	175.7	168.6	0	0	0	0	110.7	M425 L481 L513 H515 A521 A522	M425-V518 HydrophobicContact CE-CB 3.95Å; M425-V518 HydrophobicContact CE-CG1 3.47Å; M425-V518 VanDerWaalsContact CE-CG1 3.47Å; M425-V518 HydrophobicContact CE-CG2 3.6Å; M425-V518 HydrophobicContact SD-CG1 3.53Å; M425-V518 VanDerWaalsContact SD-CG1 3.53Å; L481-V518 HydrophobicContact CD1-CG1 4.46Å; L513-V518 WeakPolarHBondContact O-CG2 3.43Å; H515-V518 PolarHBondContact O-N 2.94Å; V518-A521 PolarHBondContact O-N 3.09Å; V518-A522 WeakPolarHBondContact O-CB 3.38Å; V518-A522 PolarHBondContact O-N 2.92Å
519	W	88.2	Confident	83.9	Confident	16 Å²	16	24.6 Å²	24.6	6%	0.061	13%	0.128	C	C	.	.	H	α-helix	trans	-62.8	-43.6	177.9	180	-102.9	0	0	0	111.6	H515 A516 A521 A522 T523 L542 Q543 H546 F547 H614	H515-W519 WeakPolarHBondContact O-CB 3.4Å; H515-W519 PolarHBondContact O-N 3.09Å; A516-W519 PolarHBondContact O-N 3.22Å; W519-A521 VanDerWaalsContact C-N 3.35Å; W519-A521 PolarHBondContact O-N 3.49Å; W519-A522 PolarHBondContact O-N 3.25Å; W519-T523 HydrophobicContact CD2-CG2 4.11Å; W519-T523 HydrophobicContact CH2-CG2 4.18Å; W519-T523 HydrophobicContact CZ2-CG2 3.56Å; W519-T523 WeakPolarHBondContact O-CB 3.38Å; W519-T523 WeakPolarHBondContact O-CG2 3.37Å; W519-T523 PolarHBondContact O-N 3.49Å; W519-T523 PolarHBondContact O-OG1 3.1Å; W519-L542 HydrophobicContact CH2-CD2 4.3Å; W519-L542 HydrophobicContact CH2-CG 4.07Å; W519-L542 HydrophobicContact CZ3-CD2 4.3Å; W519-L542 HydrophobicContact CZ3-CG 4Å; W519-Q543 HydrophobicContact CH2-CB 4.36Å; W519-H546 HydrophobicContact CE3-CB 4.33Å; W519-H546 AromaticContact CE3-CD2 3.7Å; W519-H546 AromaticContact CE3-CG 3.98Å; W519-H546 HydrophobicContact CZ3-CB 3.61Å; W519-H546 AromaticContact CZ3-CD2 3.76Å; W519-H546 AromaticContact CZ3-CG 3.75Å; W519-F547 AromaticContact CD2-CE2 3.67Å; W519-F547 HydrophobicContact CD2-CE2 3.67Å; W519-F547 HydrophobicContact CD2-CZ 4.24Å; W519-F547 AromaticContact CE2-CE2 3.67Å; W519-F547 HydrophobicContact CE3-CD2 4.29Å; W519-F547 AromaticContact CE3-CE2 3.6Å; W519-F547 HydrophobicContact CE3-CE2 3.6Å; W519-F547 HydrophobicContact CE3-CZ 4.25Å; W519-F547 AromaticContact CH2-CD2 3.74Å; W519-F547 HydrophobicContact CH2-CD2 3.74Å; W519-F547 AromaticContact CH2-CE2 3.63Å; W519-F547 HydrophobicContact CH2-CE2 3.63Å; W519-F547 HydrophobicContact CZ2-CD2 4.11Å; W519-F547 AromaticContact CZ2-CE2 3.67Å; W519-F547 HydrophobicContact CZ2-CE2 3.67Å; W519-F547 AromaticContact CZ3-CD2 3.83Å; W519-F547 HydrophobicContact CZ3-CD2 3.83Å; W519-F547 AromaticContact CZ3-CE2 3.6Å; W519-F547 HydrophobicContact CZ3-CE2 3.6Å; W519-H614 AromaticContact CD1-CE1 3.94Å; W519-H614 AromaticContact CD1-NE2 3.16Å; W519-H614 AromaticContact NE1-CE1 3.78Å; W519-H614 AromaticContact NE1-NE2 3.33Å; W519-H614 PolarHBondContact NE1-NE2 3.33Å
520	A	82.1	Confident	82.9	Confident	12 Å²	12	19.4 Å²	19.4	10%	0.099	11%	0.107	C	C	.	.	H	α-helix	trans	-60.3	-43.1	173	0	0	0	0	0	111.9	I472 A516 A517 A522 T523 S524	I472-A520 HydrophobicContact CD1-CB 4.21Å; A516-A520 WeakPolarHBondContact O-CB 3.11Å; A516-A520 PolarHBondContact O-N 3.13Å; A517-A520 PolarHBondContact O-N 3.42Å; A520-A522 PolarHBondContact O-N 3.22Å; A520-T523 WeakPolarHBondContact CA-OG1 3.19Å; A520-T523 PolarHBondContact O-OG1 3.49Å; A520-T523 VanDerWaalsContact O-OG1 3.05Å; A520-S524 VanDerWaalsContact O-CB 3.25Å; A520-S524 WeakPolarHBondContact O-CB 3.39Å; A520-S524 PolarHBondContact O-N 2.88Å
521	A	85	Confident	81.9	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-63.7	-41.2	175.4	0	0	0	0	0	111.6	I472 H477 V480 L481 A517 V518 W519 Y525	I472-A521 HydrophobicContact CD1-CB 4.09Å; I472-A521 HydrophobicContact CG1-CB 4.01Å; H477-A521 PolarHBondContact CD2-O 3.24Å; V480-A521 HydrophobicContact CB-CB 3.86Å; V480-A521 HydrophobicContact CG1-CB 3.67Å; V480-A521 HydrophobicContact CG2-CB 4.43Å; L481-A521 HydrophobicContact CD1-CB 4.12Å; A517-A521 WeakPolarHBondContact O-CB 3.44Å; A517-A521 PolarHBondContact O-N 2.88Å; V518-A521 PolarHBondContact O-N 3.09Å; W519-A521 VanDerWaalsContact C-N 3.35Å; W519-A521 PolarHBondContact O-N 3.49Å; A521-Y525 WeakPolarHBondContact O-CB 3.26Å; A521-Y525 PolarHBondContact O-N 3.19Å
522	A	86.6	Confident	80.6	Confident	1 Å²	1	21.3 Å²	21.3	1%	0.008	13%	0.125	C	C	.	.	H	α-helix	trans	-71	-42.9	-177.4	0	0	0	0	0	113.8	F418 T422 V518 W519 A520 Y525 I526 L542	F418-A522 HydrophobicContact CE1-CB 4.04Å; F418-A522 HydrophobicContact CZ-CB 3.67Å; T422-A522 HydrophobicContact CG2-CB 3.75Å; V518-A522 WeakPolarHBondContact O-CB 3.38Å; V518-A522 PolarHBondContact O-N 2.92Å; W519-A522 PolarHBondContact O-N 3.25Å; A520-A522 PolarHBondContact O-N 3.22Å; A522-Y525 PolarHBondContact O-N 3.39Å; A522-I526 WeakPolarHBondContact O-CB 3.46Å; A522-I526 WeakPolarHBondContact O-CG2 3.24Å; A522-I526 PolarHBondContact O-N 3.31Å; A522-L542 VanDerWaalsContact C-CD2 3.45Å; A522-L542 HydrophobicContact CB-CD1 4.29Å; A522-L542 HydrophobicContact CB-CD2 3.84Å; A522-L542 WeakPolarHBondContact O-CD2 3.02Å
523	T	79	Confident	79.3	Confident	4 Å²	4	28.2 Å²	28.2	3%	0.025	16%	0.157	C	C	.	.	H	α-helix	trans	-65.3	-39.6	175	50.9	0	0	0	0	112.3	W519 A520 I526 S527 L542 P613	W519-T523 HydrophobicContact CD2-CG2 4.11Å; W519-T523 HydrophobicContact CH2-CG2 4.18Å; W519-T523 HydrophobicContact CZ2-CG2 3.56Å; W519-T523 WeakPolarHBondContact O-CB 3.38Å; W519-T523 WeakPolarHBondContact O-CG2 3.37Å; W519-T523 PolarHBondContact O-N 3.49Å; W519-T523 PolarHBondContact O-OG1 3.1Å; A520-T523 WeakPolarHBondContact CA-OG1 3.19Å; A520-T523 PolarHBondContact O-OG1 3.49Å; A520-T523 VanDerWaalsContact O-OG1 3.05Å; T523-I526 WeakPolarHBondContact O-CG2 3.45Å; T523-S527 WeakPolarHBondContact O-CB 3.48Å; T523-S527 PolarHBondContact O-N 2.76Å; T523-S527 PolarHBondContact O-OG 3.37Å; T523-L542 HydrophobicContact CG2-CD2 3.84Å; T523-P613 HydrophobicContact CG2-CG 3.54Å
524	S	75.8	Confident	78.4	Confident	16 Å²	16	27.5 Å²	27.5	11%	0.112	15%	0.151	C	C	.	.	H	α-helix	trans	-64.3	-47.6	173.3	-179.1	0	0	0	0	111.2	H477 A520 I526 S527 L528	H477-S524 PolarHBondContact NE2-OG 3.31Å; A520-S524 VanDerWaalsContact O-CB 3.25Å; A520-S524 WeakPolarHBondContact O-CB 3.39Å; A520-S524 PolarHBondContact O-N 2.88Å; S524-I526 PolarHBondContact O-N 2.73Å; S524-S527 PolarHBondContact O-N 2.98Å; S524-L528 WeakPolarHBondContact O-CG 3.46Å; S524-L528 PolarHBondContact O-N 3.08Å; S524-L528 VanDerWaalsContact O-N 3.08Å
525	Y	81.1	Confident	77.1	Confident	27 Å²	27	29.9 Å²	29.9	11%	0.106	16%	0.16	C	C	.	.	H	α-helix	trans	-60.2	-48.4	-177.4	-177.8	-97.7	0	0	0	111.5	H414 Y415 F418 H477 A521 A522 S527 L528 A529	H414-Y525 PolarHBondContact CD2-OH 3.47Å; H414-Y525 AromaticContact NE2-CZ 3.83Å; H414-Y525 PolarHBondContact NE2-OH 3.33Å; Y415-Y525 AromaticContact CD1-CE1 3.93Å; Y415-Y525 HydrophobicContact CD1-CE1 3.93Å; Y415-Y525 HydrophobicContact CE1-CE1 4.14Å; Y415-Y525 WeakPolarHBondContact CE1-OH 3.45Å; F418-Y525 HydrophobicContact CB-CE1 4.08Å; F418-Y525 AromaticContact CD1-CD1 3.6Å; F418-Y525 HydrophobicContact CD1-CD1 3.6Å; F418-Y525 AromaticContact CD1-CE1 3.86Å; F418-Y525 HydrophobicContact CD1-CE1 3.86Å; F418-Y525 AromaticContact CD2-CD1 3.56Å; F418-Y525 HydrophobicContact CD2-CD1 3.56Å; F418-Y525 AromaticContact CD2-CE1 3.64Å; F418-Y525 HydrophobicContact CD2-CE1 3.64Å; F418-Y525 HydrophobicContact CD2-CG 4.12Å; F418-Y525 AromaticContact CE1-CD1 3.64Å; F418-Y525 HydrophobicContact CE1-CD1 3.64Å; F418-Y525 HydrophobicContact CE1-CE1 4.36Å; F418-Y525 HydrophobicContact CE1-CG 4.4Å; F418-Y525 AromaticContact CE2-CD1 3.56Å; F418-Y525 HydrophobicContact CE2-CD1 3.56Å; F418-Y525 HydrophobicContact CE2-CD2 4.5Å; F418-Y525 HydrophobicContact CE2-CE1 4.13Å; F418-Y525 AromaticContact CE2-CG 3.79Å; F418-Y525 HydrophobicContact CE2-CG 3.79Å; F418-Y525 AromaticContact CG-CD1 3.62Å; F418-Y525 HydrophobicContact CG-CD1 3.62Å; F418-Y525 AromaticContact CG-CE1 3.54Å; F418-Y525 HydrophobicContact CG-CE1 3.54Å; F418-Y525 AromaticContact CZ-CD1 3.68Å; F418-Y525 HydrophobicContact CZ-CD1 3.68Å; F418-Y525 HydrophobicContact CZ-CG 4.02Å; H477-Y525 HydrophobicContact CB-CD2 3.8Å; H477-Y525 HydrophobicContact CB-CG 4.33Å; H477-Y525 PolarHBondContact CD2-N 3.06Å; A521-Y525 WeakPolarHBondContact O-CB 3.26Å; A521-Y525 PolarHBondContact O-N 3.19Å; A522-Y525 PolarHBondContact O-N 3.39Å; Y525-S527 VanDerWaalsContact C-N 3.3Å; Y525-S527 PolarHBondContact O-N 3.44Å; Y525-L528 PolarHBondContact O-N 3.48Å; Y525-A529 WeakPolarHBondContact O-CB 3.48Å; Y525-A529 PolarHBondContact O-N 3.48Å
526	I	76.9	Confident	76	Confident	0 Å²	0	33.3 Å²	33.3	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-67.6	-32.7	-177.6	-154.4	173.4	0	0	0	112.5	F410 L419 A522 T523 S524 A529 A530 A538 Q539 L542	F410-I526 HydrophobicContact CD1-CD1 4.45Å; F410-I526 HydrophobicContact CD1-CG1 4.35Å; F410-I526 HydrophobicContact CE1-CD1 3.94Å; F410-I526 HydrophobicContact CE1-CG1 3.41Å; F410-I526 VanDerWaalsContact CE1-CG1 3.41Å; F410-I526 HydrophobicContact CE2-CD1 4.44Å; F410-I526 HydrophobicContact CE2-CG1 4.24Å; F410-I526 HydrophobicContact CZ-CD1 3.94Å; F410-I526 HydrophobicContact CZ-CG1 3.35Å; L419-I526 HydrophobicContact CD2-CD1 3.96Å; A522-I526 WeakPolarHBondContact O-CB 3.46Å; A522-I526 WeakPolarHBondContact O-CG2 3.24Å; A522-I526 PolarHBondContact O-N 3.31Å; T523-I526 WeakPolarHBondContact O-CG2 3.45Å; S524-I526 PolarHBondContact O-N 2.73Å; I526-A529 PolarHBondContact O-N 2.87Å; I526-A530 WeakPolarHBondContact O-CB 3.45Å; I526-A530 PolarHBondContact O-N 3.48Å; I526-A538 HydrophobicContact CD1-CB 4.18Å; I526-A538 VanDerWaalsContact CD1-O 3.25Å; I526-A538 WeakPolarHBondContact CD1-O 3.2Å; I526-A538 HydrophobicContact CG1-CB 4.04Å; I526-Q539 HydrophobicContact CG2-CG 4.33Å; I526-L542 HydrophobicContact CB-CD2 4.4Å; I526-L542 HydrophobicContact CD1-CB 3.76Å; I526-L542 HydrophobicContact CG2-CB 4.37Å; I526-L542 HydrophobicContact CG2-CD2 3.8Å
527	S	70.9	Confident	75.5	Confident	18 Å²	18	34.3 Å²	34.3	13%	0.126	19%	0.194	C	C	.	.	H	α-helix	trans	-73.3	-29	178.5	-54.8	0	0	0	0	112.5	T523 S524 Y525 K535 Q539	T523-S527 WeakPolarHBondContact O-CB 3.48Å; T523-S527 PolarHBondContact O-N 2.76Å; T523-S527 PolarHBondContact O-OG 3.37Å; S524-S527 PolarHBondContact O-N 2.98Å; Y525-S527 VanDerWaalsContact C-N 3.3Å; Y525-S527 PolarHBondContact O-N 3.44Å; S527-K535 WeakPolarHBondContact O-CE 3.34Å; S527-Q539 PolarHBondContact OG-NE2 2.94Å
528	L	74.5	Confident	74.8	Confident	111 Å²	111	34.2 Å²	34.2	58%	0.581	19%	0.193	S	C	*	.	H	α-helix	trans	-79.8	-32.7	173.6	-68	172.2	0	0	0	112	S524 Y525	S524-L528 WeakPolarHBondContact O-CG 3.46Å; S524-L528 PolarHBondContact O-N 3.08Å; S524-L528 VanDerWaalsContact O-N 3.08Å; Y525-L528 PolarHBondContact O-N 3.48Å
529	A	72.8	Confident	74.1	Confident	21 Å²	21	36.4 Å²	36.4	17%	0.174	20%	0.203	C	C	.	.	H	α-helix	trans	-76.7	-30.4	178.4	0	0	0	0	0	113.6	F410 Y415 Y525 I526	F410-A529 HydrophobicContact CE1-CB 4.33Å; Y415-A529 HydrophobicContact CD1-CB 4.14Å; Y415-A529 HydrophobicContact CE1-CB 3.44Å; Y415-A529 VanDerWaalsContact CE1-CB 3.44Å; Y525-A529 WeakPolarHBondContact O-CB 3.48Å; Y525-A529 PolarHBondContact O-N 3.48Å; I526-A529 PolarHBondContact O-N 2.87Å
530	A	68	Low	73.6	Confident	6 Å²	6	37 Å²	37	5%	0.05	21%	0.214	C	C	.	.	S	Bend	trans	-79.2	137.8	-180	0	0	0	0	0	111.6	F410 I526 K535 A538	F410-A530 HydrophobicContact CE2-CB 4.45Å; F410-A530 HydrophobicContact CZ-CB 4.21Å; I526-A530 WeakPolarHBondContact O-CB 3.45Å; I526-A530 PolarHBondContact O-N 3.48Å; A530-K535 HydrophobicContact CB-CG 4.45Å; A530-A538 HydrophobicContact CB-CB 3.62Å
531	P	70.1	Confident	73.8	Confident	47 Å²	47	37.7 Å²	37.7	31%	0.305	22%	0.216	S	C	.	.			trans	-52	146.5	166.9	-26.1	34.8	0	0	0	111.2	Q533 Y534 K535	P531-Q533 HydrophobicContact CB-CG 4.2Å; P531-Q533 PolarHBondContact O-N 2.89Å; P531-Q533 VanDerWaalsContact O-N 3.09Å; P531-Y534 HydrophobicContact CB-CD2 3.97Å; P531-Y534 HydrophobicContact CG-CD2 3.94Å; P531-Y534 WeakPolarHBondContact O-CA 3.48Å; P531-Y534 PolarHBondContact O-N 3.27Å; P531-K535 PolarHBondContact O-N 2.89Å
532	P	62.8	Low	73.8	Confident	70 Å²	70	37.7 Å²	37.7	46%	0.455	22%	0.216	S	C	.	.	G	3₁₀ helix	trans	-48.9	-43.5	-174.9	-29.6	35	0	0	0	114.1	Y534 K535	P532-Y534 PolarHBondContact O-N 3.01Å; P532-Y534 VanDerWaalsContact O-N 3.11Å; P532-K535 PolarHBondContact O-N 3.22Å
533	Q	61.3	Low	73.7	Confident	146 Å²	146	41.7 Å²	41.7	68%	0.682	24%	0.235	S	C	*	.	G	3₁₀ helix	trans	-62.7	-13.3	177.2	67.3	-152.4	15.3	0	0	115.6	P531	P531-Q533 HydrophobicContact CB-CG 4.2Å; P531-Q533 PolarHBondContact O-N 2.89Å; P531-Q533 VanDerWaalsContact O-N 3.09Å
534	Y	69.1	Low	74	Confident	42 Å²	42	41.9 Å²	41.9	17%	0.165	24%	0.237	C	C	.	.	G	3₁₀ helix	trans	-120.8	2.8	-175.6	-60.9	-39.1	0	0	0	113.9	K402 A405 V406 P531 P532 S536 S537 A538	K402-Y534 HydrophobicContact CB-CE1 4.11Å; K402-Y534 HydrophobicContact CD-CE1 4.27Å; A405-Y534 HydrophobicContact CB-CE1 4.37Å; A405-Y534 HydrophobicContact CB-CE2 4.13Å; V406-Y534 HydrophobicContact CG2-CD1 4.44Å; V406-Y534 HydrophobicContact CG2-CG 4.26Å; P531-Y534 HydrophobicContact CB-CD2 3.97Å; P531-Y534 HydrophobicContact CG-CD2 3.94Å; P531-Y534 WeakPolarHBondContact O-CA 3.48Å; P531-Y534 PolarHBondContact O-N 3.27Å; P532-Y534 PolarHBondContact O-N 3.01Å; P532-Y534 VanDerWaalsContact O-N 3.11Å; Y534-S536 PolarHBondContact O-N 3.03Å; Y534-S537 PolarHBondContact O-N 2.7Å; Y534-A538 WeakPolarHBondContact O-CB 3.24Å; Y534-A538 PolarHBondContact O-N 2.57Å
535	K	65.3	Low	74.7	Confident	59 Å²	59	42.8 Å²	42.8	26%	0.257	24%	0.24	S	C	.	.	H	α-helix	trans	-55.1	-48.7	-176.3	-74.2	177.6	175.7	170.3	0	113.2	S527 A530 P531 P532 A538 Q539	S527-K535 WeakPolarHBondContact O-CE 3.34Å; A530-K535 HydrophobicContact CB-CG 4.45Å; P531-K535 PolarHBondContact O-N 2.89Å; P532-K535 PolarHBondContact O-N 3.22Å; K535-A538 PolarHBondContact O-N 3.09Å; K535-Q539 WeakPolarHBondContact O-CG 3.1Å; K535-Q539 PolarHBondContact O-N 3.06Å
536	S	63.3	Low	75.2	Confident	97 Å²	97	41.9 Å²	41.9	68%	0.678	24%	0.237	S	C	*	.	H	α-helix	trans	-63	-46.3	179.4	177.7	0	0	0	0	112	Y534 A538 Q539 G540	Y534-S536 PolarHBondContact O-N 3.03Å; S536-A538 VanDerWaalsContact C-N 3.3Å; S536-A538 PolarHBondContact O-N 3.46Å; S536-Q539 PolarHBondContact O-N 3.34Å; S536-G540 PolarHBondContact O-N 3.11Å
537	S	74.6	Confident	75.6	Confident	21 Å²	21	43.8 Å²	43.8	15%	0.147	25%	0.245	C	C	.	.	H	α-helix	trans	-62.7	-36.5	176.6	-53.6	0	0	0	0	112.5	Y534 G540 L541	Y534-S537 PolarHBondContact O-N 2.7Å; S537-G540 PolarHBondContact O-N 3Å; S537-L541 PolarHBondContact O-N 3.48Å
538	A	73.2	Confident	76.4	Confident	0 Å²	0	43.2 Å²	43.2	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-65.9	-44.9	175	0	0	0	0	0	111.3	V406 F410 I526 A530 Y534 K535 S536 G540 L541 L542	V406-A538 HydrophobicContact CG1-CB 4.29Å; F410-A538 HydrophobicContact CE2-CB 3.75Å; F410-A538 HydrophobicContact CZ-CB 4Å; I526-A538 HydrophobicContact CD1-CB 4.18Å; I526-A538 VanDerWaalsContact CD1-O 3.25Å; I526-A538 WeakPolarHBondContact CD1-O 3.2Å; I526-A538 HydrophobicContact CG1-CB 4.04Å; A530-A538 HydrophobicContact CB-CB 3.62Å; Y534-A538 WeakPolarHBondContact O-CB 3.24Å; Y534-A538 PolarHBondContact O-N 2.57Å; K535-A538 PolarHBondContact O-N 3.09Å; S536-A538 VanDerWaalsContact C-N 3.3Å; S536-A538 PolarHBondContact O-N 3.46Å; A538-G540 VanDerWaalsContact C-N 3.32Å; A538-G540 PolarHBondContact O-N 3.39Å; A538-L541 WeakPolarHBondContact O-CB 3.43Å; A538-L541 PolarHBondContact O-N 3.41Å; A538-L542 PolarHBondContact O-N 3.39Å
539	Q	76.1	Confident	77.3	Confident	51 Å²	51	41.2 Å²	41.2	24%	0.238	23%	0.232	C	C	.	.	H	α-helix	trans	-59.8	-41.8	172.9	-71.8	-176	-16.4	0	0	112.3	I526 S527 K535 S536 L541 L542 Q543	I526-Q539 HydrophobicContact CG2-CG 4.33Å; S527-Q539 PolarHBondContact OG-NE2 2.94Å; K535-Q539 WeakPolarHBondContact O-CG 3.1Å; K535-Q539 PolarHBondContact O-N 3.06Å; S536-Q539 PolarHBondContact O-N 3.34Å; Q539-L541 VanDerWaalsContact C-N 3.33Å; Q539-L541 PolarHBondContact O-N 2.97Å; Q539-L542 PolarHBondContact O-N 2.85Å; Q539-Q543 WeakPolarHBondContact O-CB 3.2Å; Q539-Q543 PolarHBondContact O-N 3.36Å
540	G	77.9	Confident	78.3	Confident	28 Å²	28	40.2 Å²	40.2	29%	0.289	22%	0.224	S	C	.	.	H	α-helix	trans	-60	-40.9	174	0	0	0	0	0	112.8	S536 S537 A538 Q543 G544	S536-G540 PolarHBondContact O-N 3.11Å; S537-G540 PolarHBondContact O-N 3Å; A538-G540 VanDerWaalsContact C-N 3.32Å; A538-G540 PolarHBondContact O-N 3.39Å; G540-Q543 PolarHBondContact O-N 2.65Å; G540-G544 PolarHBondContact O-N 3.22Å
541	L	84.5	Confident	79.5	Confident	26 Å²	26	42.8 Å²	42.8	14%	0.136	23%	0.232	C	C	.	.	H	α-helix	trans	-62.1	-45.1	173.7	177.2	63.5	0	0	0	111.6	W403 V406 F410 L419 S537 A538 Q539 G544 L545	W403-L541 HydrophobicContact CZ3-CB 4.33Å; V406-L541 HydrophobicContact CG1-CD2 3.93Å; F410-L541 HydrophobicContact CD2-CD2 4.2Å; F410-L541 HydrophobicContact CG-CD2 4.45Å; L419-L541 HydrophobicContact CD1-CD2 4.34Å; S537-L541 PolarHBondContact O-N 3.48Å; A538-L541 WeakPolarHBondContact O-CB 3.43Å; A538-L541 PolarHBondContact O-N 3.41Å; Q539-L541 VanDerWaalsContact C-N 3.33Å; Q539-L541 PolarHBondContact O-N 2.97Å; L541-G544 PolarHBondContact O-N 3.11Å; L541-L545 HydrophobicContact CD1-CD1 4.06Å; L541-L545 HydrophobicContact CD1-CG 4.32Å; L541-L545 HydrophobicContact CG-CD1 4.02Å; L541-L545 WeakPolarHBondContact O-CB 3.46Å; L541-L545 WeakPolarHBondContact O-CG 3.49Å; L541-L545 PolarHBondContact O-N 3.37Å
542	L	85.4	Confident	80.6	Confident	0 Å²	0	40.5 Å²	40.5	0%	0	22%	0.217	C	C	.	.	H	α-helix	trans	-62.8	-44.9	177.6	-179.8	65.5	0	0	0	112.2	L419 T422 W519 A522 T523 I526 A538 Q539 L545 H546	L419-L542 HydrophobicContact CD2-CD1 4.18Å; T422-L542 HydrophobicContact CG2-CD1 4.01Å; W519-L542 HydrophobicContact CH2-CD2 4.3Å; W519-L542 HydrophobicContact CH2-CG 4.07Å; W519-L542 HydrophobicContact CZ3-CD2 4.3Å; W519-L542 HydrophobicContact CZ3-CG 4Å; A522-L542 VanDerWaalsContact C-CD2 3.45Å; A522-L542 HydrophobicContact CB-CD1 4.29Å; A522-L542 HydrophobicContact CB-CD2 3.84Å; A522-L542 WeakPolarHBondContact O-CD2 3.02Å; T523-L542 HydrophobicContact CG2-CD2 3.84Å; I526-L542 HydrophobicContact CB-CD2 4.4Å; I526-L542 HydrophobicContact CD1-CB 3.76Å; I526-L542 HydrophobicContact CG2-CB 4.37Å; I526-L542 HydrophobicContact CG2-CD2 3.8Å; A538-L542 PolarHBondContact O-N 3.39Å; Q539-L542 PolarHBondContact O-N 2.85Å; L542-L545 PolarHBondContact O-N 3.47Å; L542-H546 WeakPolarHBondContact O-CB 3.43Å; L542-H546 PolarHBondContact O-N 3.14Å
543	Q	84.7	Confident	82.2	Confident	86 Å²	86	37.8 Å²	37.8	40%	0.402	20%	0.2	S	C	.	.	H	α-helix	trans	-58.3	-48.2	175.1	-176.2	71.9	18.2	0	0	111.1	W519 Q539 G540 L545 H546 F547 G548	W519-Q543 HydrophobicContact CH2-CB 4.36Å; Q539-Q543 WeakPolarHBondContact O-CB 3.2Å; Q539-Q543 PolarHBondContact O-N 3.36Å; G540-Q543 PolarHBondContact O-N 2.65Å; Q543-L545 VanDerWaalsContact C-N 3.32Å; Q543-L545 PolarHBondContact O-N 3.33Å; Q543-H546 PolarHBondContact O-N 3.13Å; Q543-F547 VanDerWaalsContact CD-CD2 3.47Å; Q543-F547 PolarHBondContact O-N 3.31Å; Q543-G548 PolarHBondContact O-N 2.99Å
544	G	85.1	Confident	83.8	Confident	7 Å²	7	30.8 Å²	30.8	7%	0.072	17%	0.167	C	C	.	.	I	π-helix	trans	-60	-40.6	176.6	0	0	0	0	0	112.8	F111 G540 L541 G548 L549	F111-G544 VanDerWaalsContact CE2-CA 3.49Å; G540-G544 PolarHBondContact O-N 3.22Å; L541-G544 PolarHBondContact O-N 3.11Å; G544-G548 CarbonylContact O-C 3.56Å; G544-G548 WeakPolarHBondContact O-CA 3.39Å; G544-G548 PolarHBondContact O-N 3.32Å; G544-L549 PolarHBondContact O-N 3.27Å
545	L	90.7	Very high	85.1	Confident	35 Å²	35	28.9 Å²	28.9	18%	0.183	16%	0.16	C	C	.	.	I	π-helix	trans	-70.9	-46.5	177.9	-79.5	168	0	0	0	112.8	L419 L541 L542 Q543 L549 G550	L419-L545 HydrophobicContact CB-CD1 4.18Å; L419-L545 HydrophobicContact CD1-CD1 4.02Å; L419-L545 HydrophobicContact CD2-CD1 3.91Å; L419-L545 HydrophobicContact CG-CD1 4.27Å; L541-L545 HydrophobicContact CD1-CD1 4.06Å; L541-L545 HydrophobicContact CD1-CG 4.32Å; L541-L545 HydrophobicContact CG-CD1 4.02Å; L541-L545 WeakPolarHBondContact O-CB 3.46Å; L541-L545 WeakPolarHBondContact O-CG 3.49Å; L541-L545 PolarHBondContact O-N 3.37Å; L542-L545 PolarHBondContact O-N 3.47Å; Q543-L545 VanDerWaalsContact C-N 3.32Å; Q543-L545 PolarHBondContact O-N 3.33Å; L545-L549 HydrophobicContact CD2-CD2 4.02Å; L545-G550 WeakPolarHBondContact O-CA 3.37Å; L545-G550 PolarHBondContact O-N 3.45Å
546	H	90.8	Very high	86.6	Confident	8 Å²	8	28 Å²	28	4%	0.037	16%	0.158	C	C	.	.	I	π-helix	trans	-80	-57.2	-174.2	-172.1	82.2	0	0	0	112.4	T422 G426 W519 L542 Q543 G550 R551	T422-H546 PolarHBondContact O-ND1 2.97Å; G426-H546 WeakPolarHBondContact CA-O 3.26Å; G426-H546 PolarHBondContact N-CE1 3.04Å; G426-H546 VanDerWaalsContact N-CE1 3.32Å; G426-H546 PolarHBondContact N-ND1 3.14Å; W519-H546 HydrophobicContact CE3-CB 4.33Å; W519-H546 AromaticContact CE3-CD2 3.7Å; W519-H546 AromaticContact CE3-CG 3.98Å; W519-H546 HydrophobicContact CZ3-CB 3.61Å; W519-H546 AromaticContact CZ3-CD2 3.76Å; W519-H546 AromaticContact CZ3-CG 3.75Å; L542-H546 WeakPolarHBondContact O-CB 3.43Å; L542-H546 PolarHBondContact O-N 3.14Å; Q543-H546 PolarHBondContact O-N 3.13Å; H546-G550 WeakPolarHBondContact O-CA 3.31Å; H546-R551 PolarHBondContact O-N 3.37Å
547	F	87.1	Confident	88.2	Confident	40 Å²	40	28.5 Å²	28.5	18%	0.175	15%	0.148	C	C	.	.	I	π-helix	trans	-89.6	-24.3	-174.3	-72.5	-67.2	0	0	0	113.8	P107 H515 W519 Q543 R551	P107-F547 VanDerWaalsContact CB-O 3.32Å; P107-F547 WeakPolarHBondContact CB-O 3.47Å; H515-F547 AromaticContact CE1-CZ 3.99Å; H515-F547 AromaticContact NE2-CE1 3.29Å; H515-F547 VanDerWaalsContact NE2-CE1 3.29Å; H515-F547 WeakPolarHBondContact NE2-CE1 3.33Å; H515-F547 AromaticContact NE2-CZ 3.35Å; H515-F547 WeakPolarHBondContact NE2-CZ 2.93Å; W519-F547 AromaticContact CD2-CE2 3.67Å; W519-F547 HydrophobicContact CD2-CE2 3.67Å; W519-F547 HydrophobicContact CD2-CZ 4.24Å; W519-F547 AromaticContact CE2-CE2 3.67Å; W519-F547 HydrophobicContact CE3-CD2 4.29Å; W519-F547 AromaticContact CE3-CE2 3.6Å; W519-F547 HydrophobicContact CE3-CE2 3.6Å; W519-F547 HydrophobicContact CE3-CZ 4.25Å; W519-F547 AromaticContact CH2-CD2 3.74Å; W519-F547 HydrophobicContact CH2-CD2 3.74Å; W519-F547 AromaticContact CH2-CE2 3.63Å; W519-F547 HydrophobicContact CH2-CE2 3.63Å; W519-F547 HydrophobicContact CZ2-CD2 4.11Å; W519-F547 AromaticContact CZ2-CE2 3.67Å; W519-F547 HydrophobicContact CZ2-CE2 3.67Å; W519-F547 AromaticContact CZ3-CD2 3.83Å; W519-F547 HydrophobicContact CZ3-CD2 3.83Å; W519-F547 AromaticContact CZ3-CE2 3.6Å; W519-F547 HydrophobicContact CZ3-CE2 3.6Å; Q543-F547 VanDerWaalsContact CD-CD2 3.47Å; Q543-F547 PolarHBondContact O-N 3.31Å; F547-R551 VanDerWaalsContact O-CB 3.24Å; F547-R551 WeakPolarHBondContact O-CB 3.46Å
548	G	87.8	Confident	89.2	Confident	6 Å²	6	27.6 Å²	27.6	6%	0.062	14%	0.142	C	C	.	.	I	π-helix	trans	-82.5	-90.3	172.2	0	0	0	0	0	111.1	Q543 G544 G550 G552	Q543-G548 PolarHBondContact O-N 2.99Å; G544-G548 CarbonylContact O-C 3.56Å; G544-G548 WeakPolarHBondContact O-CA 3.39Å; G544-G548 PolarHBondContact O-N 3.32Å; G548-G550 PolarHBondContact O-N 2.58Å; G548-G552 PolarHBondContact O-N 3.15Å
549	L	91.7	Very high	90.3	Very high	69 Å²	69	27.6 Å²	27.6	36%	0.361	14%	0.142	S	C	.	.	I	π-helix	trans	-57.8	-48.5	-175	-176.4	63.6	0	0	0	112.4	F108 G544 L545 C553	F108-L549 HydrophobicContact CE1-CD1 3.62Å; F108-L549 HydrophobicContact CZ-CD1 4.26Å; G544-L549 PolarHBondContact O-N 3.27Å; L545-L549 HydrophobicContact CD2-CD2 4.02Å; L549-C553 WeakPolarHBondContact O-CB 3.47Å; L549-C553 PolarHBondContact O-N 2.95Å; L549-C553 PolarHBondContact O-SG 2.02Å
550	G	94	Very high	91.3	Very high	0 Å²	0	28.7 Å²	28.7	0%	0	15%	0.149	C	C	.	.	I	π-helix	trans	-60.1	-62.1	-178.5	0	0	0	0	0	111.5	G426 L427 L545 H546 G548 G552 C553 G554	G426-G550 CarbonylContact O-C 3.59Å; L427-G550 VanDerWaalsContact CA-O 3.26Å; L427-G550 WeakPolarHBondContact CA-O 3.48Å; L427-G550 PolarHBondContact N-O 2.91Å; L545-G550 WeakPolarHBondContact O-CA 3.37Å; L545-G550 PolarHBondContact O-N 3.45Å; H546-G550 WeakPolarHBondContact O-CA 3.31Å; G548-G550 PolarHBondContact O-N 2.58Å; G550-G552 VanDerWaalsContact C-N 3.32Å; G550-G552 PolarHBondContact O-N 3.43Å; G550-C553 PolarHBondContact O-N 3.36Å; G550-G554 PolarHBondContact O-N 3.19Å
551	R	93.1	Very high	92.2	Very high	60 Å²	60	31.5 Å²	31.5	23%	0.226	16%	0.155	C	C	.	.	H	α-helix	trans	-56.7	-43.4	179.2	-170	-173.8	178.9	-175.1	0.9	112.6	G426 G430 F433 H546 F547 G554 A555	G426-R551 VanDerWaalsContact O-CA 3.27Å; G426-R551 WeakPolarHBondContact O-CA 3.33Å; G426-R551 PolarHBondContact O-N 3.21Å; G430-R551 VanDerWaalsContact CA-O 3.26Å; G430-R551 WeakPolarHBondContact CA-O 3.23Å; F433-R551 VanDerWaalsContact CD2-NH2 3.29Å; H546-R551 PolarHBondContact O-N 3.37Å; F547-R551 VanDerWaalsContact O-CB 3.24Å; F547-R551 WeakPolarHBondContact O-CB 3.46Å; R551-G554 PolarHBondContact O-N 3.36Å; R551-A555 PolarHBondContact O-N 2.91Å
552	G	94.3	Very high	92.8	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-61.2	-49	177	0	0	0	0	0	112.2	G104 G548 G550 G554 A555 L556	G104-G552 WeakPolarHBondContact O-CA 3.38Å; G548-G552 PolarHBondContact O-N 3.15Å; G550-G552 VanDerWaalsContact C-N 3.32Å; G550-G552 PolarHBondContact O-N 3.43Å; G552-G554 VanDerWaalsContact C-N 3.31Å; G552-G554 PolarHBondContact O-N 3.11Å; G552-A555 PolarHBondContact O-N 3.5Å; G552-L556 WeakPolarHBondContact O-CG 3.21Å; G552-L556 PolarHBondContact O-N 3.4Å
553	C	96	Very high	93.2	Very high	12 Å²	12	32.5 Å²	32.5	8%	0.081	16%	0.163	C	C	.	.	H	α-helix	trans	-60.7	-38	175	-75.7	0	0	0	0	112.6	L549 G550 A555 L556 F557	L549-C553 WeakPolarHBondContact O-CB 3.47Å; L549-C553 PolarHBondContact O-N 2.95Å; L549-C553 PolarHBondContact O-SG 2.02Å; G550-C553 PolarHBondContact O-N 3.36Å; C553-A555 PolarHBondContact O-N 3.12Å; C553-L556 PolarHBondContact O-N 2.78Å; C553-F557 HydrophobicContact CB-CD2 3.84Å; C553-F557 HydrophobicContact CB-CE2 3.83Å; C553-F557 WeakPolarHBondContact O-CB 3.49Å; C553-F557 WeakPolarHBondContact O-CD2 3.47Å; C553-F557 PolarHBondContact O-N 3Å
554	G	96	Very high	93.6	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-59.7	-44	176.7	0	0	0	0	0	113	L427 L431 G550 R551 G552 G558	L427-G554 VanDerWaalsContact O-CA 3.28Å; L427-G554 WeakPolarHBondContact O-CA 3.33Å; L431-G554 VanDerWaalsContact CD2-O 3.28Å; L431-G554 WeakPolarHBondContact CD2-O 3.48Å; G550-G554 PolarHBondContact O-N 3.19Å; R551-G554 PolarHBondContact O-N 3.36Å; G552-G554 VanDerWaalsContact C-N 3.31Å; G552-G554 PolarHBondContact O-N 3.11Å; G554-G558 WeakPolarHBondContact O-CA 3.23Å; G554-G558 PolarHBondContact O-N 2.85Å
555	A	96.1	Very high	94	Very high	2 Å²	2	41.4 Å²	41.4	2%	0.017	20%	0.198	C	C	.	.	H	α-helix	trans	-68.9	-45.3	175	0	0	0	0	0	112	G100 V103 C434 F435 R551 G552 C553 G559	G100-A555 VanDerWaalsContact CA-O 3.31Å; G100-A555 WeakPolarHBondContact CA-O 3.28Å; V103-A555 HydrophobicContact CB-CB 4.47Å; V103-A555 HydrophobicContact CG1-CB 4.3Å; C434-A555 HydrophobicContact CB-CB 3.99Å; F435-A555 WeakPolarHBondContact CE2-O 3.42Å; R551-A555 PolarHBondContact O-N 2.91Å; G552-A555 PolarHBondContact O-N 3.5Å; C553-A555 PolarHBondContact O-N 3.12Å; A555-G559 PolarHBondContact O-N 3.2Å
556	L	96	Very high	94.2	Very high	41 Å²	41	39.7 Å²	39.7	22%	0.215	19%	0.189	C	C	.	.	H	α-helix	trans	-63.5	-60.6	-178.9	-72.6	172.2	0	0	0	112.8	I101 F108 G552 C553 G558 G559 I560	I101-L556 HydrophobicContact CB-CD2 4.1Å; I101-L556 HydrophobicContact CG1-CD2 3.64Å; F108-L556 HydrophobicContact CE2-CD1 3.52Å; F108-L556 HydrophobicContact CE2-CG 4.5Å; F108-L556 HydrophobicContact CZ-CD1 3.97Å; G552-L556 WeakPolarHBondContact O-CG 3.21Å; G552-L556 PolarHBondContact O-N 3.4Å; C553-L556 PolarHBondContact O-N 2.78Å; L556-G558 VanDerWaalsContact C-N 3.3Å; L556-G558 PolarHBondContact O-N 2.66Å; L556-G559 PolarHBondContact O-N 3.23Å; L556-I560 WeakPolarHBondContact O-CG1 3.4Å; L556-I560 PolarHBondContact O-N 2.77Å; L556-I560 VanDerWaalsContact O-N 3.15Å
557	F	96.5	Very high	94.4	Very high	107 Å²	107	39.3 Å²	39.3	47%	0.469	19%	0.187	S	C	.	.	H	α-helix	trans	-67.7	-35.5	-178.4	-63.3	-48.4	0	0	0	111.3	C553 G559 I560 M561	C553-F557 HydrophobicContact CB-CD2 3.84Å; C553-F557 HydrophobicContact CB-CE2 3.83Å; C553-F557 WeakPolarHBondContact O-CB 3.49Å; C553-F557 WeakPolarHBondContact O-CD2 3.47Å; C553-F557 PolarHBondContact O-N 3Å; F557-G559 PolarHBondContact O-N 3.11Å; F557-I560 HydrophobicContact CD1-CD1 4.47Å; F557-I560 PolarHBondContact O-N 2.96Å; F557-M561 WeakPolarHBondContact O-CB 3.19Å; F557-M561 VanDerWaalsContact O-CG 3.32Å; F557-M561 WeakPolarHBondContact O-CG 3.27Å; F557-M561 PolarHBondContact O-N 2.82Å
558	G	96.3	Very high	94.7	Very high	2 Å²	2	41.6 Å²	41.6	2%	0.021	20%	0.195	C	C	.	.	H	α-helix	trans	-54	-51.4	170.8	0	0	0	0	0	112.1	G554 L556 I560 M561 I562	G554-G558 WeakPolarHBondContact O-CA 3.23Å; G554-G558 PolarHBondContact O-N 2.85Å; L556-G558 VanDerWaalsContact C-N 3.3Å; L556-G558 PolarHBondContact O-N 2.66Å; G558-I560 PolarHBondContact O-N 2.91Å; G558-M561 PolarHBondContact O-N 2.87Å; G558-I562 VanDerWaalsContact O-CB 3.31Å; G558-I562 WeakPolarHBondContact O-CB 3.47Å; G558-I562 WeakPolarHBondContact O-CD1 3.14Å; G558-I562 WeakPolarHBondContact O-CG1 3.48Å; G558-I562 PolarHBondContact O-N 3.13Å
559	G	96.9	Very high	95	Very high	0 Å²	0	46.1 Å²	46.1	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-59.7	-45.9	179.2	0	0	0	0	0	113.2	P96 T97 F435 A555 L556 F557 M561 I562 T563	P96-G559 WeakPolarHBondContact O-CA 3.37Å; T97-G559 PolarHBondContact N-O 3.11Å; T97-G559 PolarHBondContact OG1-O 3.45Å; F435-G559 VanDerWaalsContact CE2-N 3.27Å; A555-G559 PolarHBondContact O-N 3.2Å; L556-G559 PolarHBondContact O-N 3.23Å; F557-G559 PolarHBondContact O-N 3.11Å; G559-M561 PolarHBondContact O-N 2.99Å; G559-I562 PolarHBondContact O-N 3.45Å; G559-T563 PolarHBondContact O-N 3.49Å; G559-T563 VanDerWaalsContact O-N 3.08Å; G559-T563 PolarHBondContact O-OG1 3.21Å
560	I	96.6	Very high	95.3	Very high	73 Å²	73	43 Å²	43	37%	0.374	20%	0.199	S	C	.	.	H	α-helix	trans	-60	-47	178.5	-65.7	167.2	0	0	0	111.1	T97 L556 F557 G558	T97-I560 HydrophobicContact CG2-CG1 3.86Å; T97-I560 WeakPolarHBondContact OG1-CA 3.44Å; L556-I560 WeakPolarHBondContact O-CG1 3.4Å; L556-I560 PolarHBondContact O-N 2.77Å; L556-I560 VanDerWaalsContact O-N 3.15Å; F557-I560 HydrophobicContact CD1-CD1 4.47Å; F557-I560 PolarHBondContact O-N 2.96Å; G558-I560 PolarHBondContact O-N 2.91Å
561	M	96.7	Very high	95.4	Very high	87 Å²	87	43 Å²	43	43%	0.429	20%	0.199	S	C	.	.	H	α-helix	trans	-70	-44.5	-179	-67	178.3	68.9	0	0	111.9	F557 G558 G559 T563 R564 T565 V570	F557-M561 WeakPolarHBondContact O-CB 3.19Å; F557-M561 VanDerWaalsContact O-CG 3.32Å; F557-M561 WeakPolarHBondContact O-CG 3.27Å; F557-M561 PolarHBondContact O-N 2.82Å; G558-M561 PolarHBondContact O-N 2.87Å; G559-M561 PolarHBondContact O-N 2.99Å; M561-T563 PolarHBondContact O-N 2.84Å; M561-R564 PolarHBondContact O-N 2.94Å; M561-T565 PolarHBondContact O-N 3.45Å; M561-T565 PolarHBondContact O-OG1 3.37Å; M561-T565 VanDerWaalsContact O-OG1 3.1Å; M561-V570 HydrophobicContact CB-CG2 3.49Å; M561-V570 VanDerWaalsContact CB-CG2 3.49Å; M561-V570 HydrophobicContact CE-CG2 4.4Å
562	I	96.8	Very high	95.5	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-60.8	-36.4	-179	-69	167.8	0	0	0	111	P96 G214 F435 G558 G559 R564 G566 T567 V570	P96-I562 HydrophobicContact CB-CB 3.91Å; P96-I562 HydrophobicContact CB-CG2 3.73Å; P96-I562 HydrophobicContact CG-CB 4.29Å; P96-I562 HydrophobicContact CG-CG2 3.63Å; G214-I562 WeakPolarHBondContact O-CG2 3.16Å; F435-I562 HydrophobicContact CB-CD1 3.67Å; F435-I562 HydrophobicContact CD1-CD1 3.52Å; F435-I562 HydrophobicContact CD2-CD1 3.39Å; F435-I562 HydrophobicContact CE1-CD1 3.97Å; F435-I562 HydrophobicContact CE2-CD1 3.86Å; F435-I562 HydrophobicContact CG-CD1 3.21Å; F435-I562 HydrophobicContact CZ-CD1 4.13Å; G558-I562 VanDerWaalsContact O-CB 3.31Å; G558-I562 WeakPolarHBondContact O-CB 3.47Å; G558-I562 WeakPolarHBondContact O-CD1 3.14Å; G558-I562 WeakPolarHBondContact O-CG1 3.48Å; G558-I562 PolarHBondContact O-N 3.13Å; G559-I562 PolarHBondContact O-N 3.45Å; I562-R564 PolarHBondContact O-N 3.42Å; I562-R564 VanDerWaalsContact O-N 3.14Å; I562-G566 VanDerWaalsContact O-CA 3.31Å; I562-G566 WeakPolarHBondContact O-CA 3.27Å; I562-G566 PolarHBondContact O-N 3.42Å; I562-T567 HydrophobicContact CD1-CG2 3.82Å; I562-T567 HydrophobicContact CG1-CG2 4.14Å; I562-T567 HydrophobicContact CG2-CG2 3.83Å; I562-V570 HydrophobicContact CG1-CB 3.94Å; I562-V570 HydrophobicContact CG1-CG1 4.2Å; I562-V570 HydrophobicContact CG1-CG2 3.68Å
563	T	94.7	Very high	95.6	Very high	47 Å²	47	46 Å²	46	29%	0.288	22%	0.218	S	C	.	.	H	α-helix	trans	-58.6	-27.6	177.9	-56.5	0	0	0	0	112.4	T97 G559 M561	T97-T563 PolarHBondContact N-OG1 2.84Å; T97-T563 VanDerWaalsContact N-OG1 3.1Å; T97-T563 PolarHBondContact OG1-OG1 3.33Å; G559-T563 PolarHBondContact O-N 3.49Å; G559-T563 VanDerWaalsContact O-N 3.08Å; G559-T563 PolarHBondContact O-OG1 3.21Å; M561-T563 PolarHBondContact O-N 2.84Å
564	R	93.1	Very high	95.6	Very high	214 Å²	214	45.8 Å²	45.8	81%	0.808	22%	0.215	S	C	*	.	H	α-helix	trans	-98.7	-41.5	-179.4	-61.4	-174.5	-177.1	-178.6	1	113.6	M561 I562	M561-R564 PolarHBondContact O-N 2.94Å; I562-R564 PolarHBondContact O-N 3.42Å; I562-R564 VanDerWaalsContact O-N 3.14Å
565	T	93.7	Very high	95.7	Very high	66 Å²	66	45.8 Å²	45.8	41%	0.405	22%	0.215	S	C	.	.	H	α-helix	trans	-114.4	-9.5	-168.5	62.2	0	0	0	0	114.3	M561	M561-T565 PolarHBondContact O-N 3.45Å; M561-T565 PolarHBondContact O-OG1 3.37Å; M561-T565 VanDerWaalsContact O-OG1 3.1Å
566	G	93.7	Very high	95.7	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	77.3	170.5	-169.9	0	0	0	0	0	114.1	P213 I562 V570	P213-G566 CarbonylContact O-C 3.59Å; P213-G566 VanDerWaalsContact O-CA 3.31Å; P213-G566 WeakPolarHBondContact O-CA 3.35Å; I562-G566 VanDerWaalsContact O-CA 3.31Å; I562-G566 WeakPolarHBondContact O-CA 3.27Å; I562-G566 PolarHBondContact O-N 3.42Å; G566-V570 WeakPolarHBondContact O-CG2 3.42Å; G566-V570 PolarHBondContact O-N 3.22Å
567	T	94.8	Very high	95.7	Very high	0 Å²	0	50.5 Å²	50.5	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-68	-40.1	-175.3	42.4	0	0	0	0	113	P213 G214 F435 H439 I562 M569 V570 F571	P213-T567 PolarHBondContact O-N 3.14Å; P213-T567 PolarHBondContact O-OG1 2.95Å; G214-T567 PolarHBondContact N-OG1 2.73Å; F435-T567 HydrophobicContact CB-CG2 4.49Å; H439-T567 HydrophobicContact CB-CG2 4.06Å; H439-T567 WeakPolarHBondContact ND1-CB 3.5Å; H439-T567 PolarHBondContact ND1-OG1 3.17Å; I562-T567 HydrophobicContact CD1-CG2 3.82Å; I562-T567 HydrophobicContact CG1-CG2 4.14Å; I562-T567 HydrophobicContact CG2-CG2 3.83Å; T567-M569 VanDerWaalsContact C-N 3.33Å; T567-M569 PolarHBondContact O-N 3.37Å; T567-V570 PolarHBondContact O-N 3.46Å; T567-F571 WeakPolarHBondContact O-CG 3.31Å; T567-F571 PolarHBondContact O-N 2.99Å
568	R	94.4	Very high	95.7	Very high	88 Å²	88	45.4 Å²	45.4	33%	0.332	22%	0.217	S	C	.	.	H	α-helix	trans	-56.3	-45.8	-179.1	-70.1	-175.5	174.4	156.9	3.4	112.1	P213 R572	P213-R568 HydrophobicContact CG-CG 4.45Å; R568-R572 WeakPolarHBondContact O-CG 3.4Å; R568-R572 PolarHBondContact O-N 2.9Å; R568-R572 VanDerWaalsContact O-N 3.14Å
569	M	94.4	Very high	95.7	Very high	101 Å²	101	48.7 Å²	48.7	50%	0.498	23%	0.234	S	C	.	.	H	α-helix	trans	-69.1	-40	-179.9	-71.9	-56.9	-64.7	0	0	112.1	T567 R572 S573	T567-M569 VanDerWaalsContact C-N 3.33Å; T567-M569 PolarHBondContact O-N 3.37Å; M569-R572 PolarHBondContact O-N 3.31Å; M569-S573 WeakPolarHBondContact O-CB 3.1Å; M569-S573 PolarHBondContact O-N 3.03Å; M569-S573 PolarHBondContact O-OG 3.28Å
570	V	96.9	Very high	95.7	Very high	3 Å²	3	52.9 Å²	52.9	2%	0.018	26%	0.259	C	S	.	.	H	α-helix	trans	-64.8	-46.4	178.7	174.9	0	0	0	0	111.2	L431 M561 I562 G566 T567 R572 S573 Y574	L431-V570 HydrophobicContact CD2-CG1 3.92Å; M561-V570 HydrophobicContact CB-CG2 3.49Å; M561-V570 VanDerWaalsContact CB-CG2 3.49Å; M561-V570 HydrophobicContact CE-CG2 4.4Å; I562-V570 HydrophobicContact CG1-CB 3.94Å; I562-V570 HydrophobicContact CG1-CG1 4.2Å; I562-V570 HydrophobicContact CG1-CG2 3.68Å; G566-V570 WeakPolarHBondContact O-CG2 3.42Å; G566-V570 PolarHBondContact O-N 3.22Å; T567-V570 PolarHBondContact O-N 3.46Å; V570-R572 PolarHBondContact O-N 3.4Å; V570-S573 WeakPolarHBondContact CA-OG 3.29Å; V570-S573 PolarHBondContact O-N 2.93Å; V570-S573 PolarHBondContact O-OG 3.49Å; V570-Y574 PolarHBondContact O-N 3.39Å
571	F	96.1	Very high	95.7	Very high	1 Å²	1	50.1 Å²	50.1	0%	0.004	25%	0.245	C	C	.	.	H	α-helix	trans	-61.9	-40.7	176.2	-65.6	-27.8	0	0	0	112.5	F435 H439 F492 I495 T567 Y574 G575	F435-F571 HydrophobicContact CB-CZ 4.24Å; H439-F571 HydrophobicContact CB-CE2 3.75Å; H439-F571 HydrophobicContact CB-CZ 4.35Å; H439-F571 AromaticContact CG-CE2 3.79Å; F492-F571 WeakPolarHBondContact CB-O 3.31Å; F492-F571 HydrophobicContact CD1-CB 4.13Å; F492-F571 AromaticContact CD1-CD1 3.76Å; F492-F571 HydrophobicContact CD1-CD1 3.76Å; F492-F571 HydrophobicContact CD1-CG 4.21Å; F492-F571 AromaticContact CE1-CD1 3.89Å; F492-F571 HydrophobicContact CE1-CD1 3.89Å; F492-F571 HydrophobicContact CE1-CE1 4.32Å; I495-F571 HydrophobicContact CG2-CD2 3.61Å; I495-F571 HydrophobicContact CG2-CE2 3.68Å; I495-F571 HydrophobicContact CG2-CG 4.49Å; T567-F571 WeakPolarHBondContact O-CG 3.31Å; T567-F571 PolarHBondContact O-N 2.99Å; F571-Y574 PolarHBondContact O-N 3.17Å; F571-G575 PolarHBondContact O-N 3.38Å
572	R	95.9	Very high	95.7	Very high	74 Å²	74	47.1 Å²	47.1	28%	0.279	23%	0.23	S	C	.	.	H	α-helix	trans	-60.9	-48.3	172.8	-72.3	177.2	-170.6	167.2	7.2	112.3	L493 S496 R568 M569 V570 Y574 G575 F576	L493-R572 HydrophobicContact CD2-CG 4.46Å; S496-R572 PolarHBondContact O-NH2 3.24Å; S496-R572 WeakPolarHBondContact OG-CG 3.36Å; S496-R572 PolarHBondContact OG-NE 3.26Å; R568-R572 WeakPolarHBondContact O-CG 3.4Å; R568-R572 PolarHBondContact O-N 2.9Å; R568-R572 VanDerWaalsContact O-N 3.14Å; M569-R572 PolarHBondContact O-N 3.31Å; V570-R572 PolarHBondContact O-N 3.4Å; R572-Y574 VanDerWaalsContact C-N 3.29Å; R572-Y574 PolarHBondContact O-N 3.14Å; R572-G575 PolarHBondContact O-N 3.39Å; R572-G575 VanDerWaalsContact O-N 3.17Å; R572-F576 WeakPolarHBondContact O-CD2 3.31Å; R572-F576 PolarHBondContact O-N 2.89Å
573	S	96.2	Very high	95.6	Very high	48 Å²	48	50.7 Å²	50.7	34%	0.336	25%	0.252	S	S	.	.	H	α-helix	trans	-60.1	-41.2	-178.2	71.7	0	0	0	0	111.7	M569 V570 F576 A577	M569-S573 WeakPolarHBondContact O-CB 3.1Å; M569-S573 PolarHBondContact O-N 3.03Å; M569-S573 PolarHBondContact O-OG 3.28Å; V570-S573 WeakPolarHBondContact CA-OG 3.29Å; V570-S573 PolarHBondContact O-N 2.93Å; V570-S573 PolarHBondContact O-OG 3.49Å; S573-F576 PolarHBondContact O-N 3.12Å; S573-A577 VanDerWaalsContact O-CB 3.26Å; S573-A577 WeakPolarHBondContact O-CB 3.43Å; S573-A577 PolarHBondContact O-N 2.88Å
574	Y	96.9	Very high	95.5	Very high	7 Å²	7	52.9 Å²	52.9	3%	0.027	26%	0.261	C	S	.	.	H	α-helix	trans	-66.1	-43.7	175.4	-177.6	-90.1	0	0	0	111.7	W424 L427 G428 L431 F492 V570 F571 R572 F576 A577 C578	W424-Y574 AromaticContact CE2-CE2 3.79Å; W424-Y574 HydrophobicContact CZ2-CD2 4.09Å; W424-Y574 HydrophobicContact CZ2-CE2 4.11Å; W424-Y574 AromaticContact NE1-CE2 3.39Å; W424-Y574 AromaticContact NE1-CZ 3.68Å; W424-Y574 PolarHBondContact O-OH 3.49Å; L427-Y574 HydrophobicContact CB-CE2 4.41Å; L427-Y574 HydrophobicContact CD2-CD2 3.84Å; L427-Y574 HydrophobicContact CD2-CE2 3.73Å; G428-Y574 WeakPolarHBondContact CA-OH 3.17Å; G428-Y574 PolarHBondContact N-OH 3.44Å; L431-Y574 HydrophobicContact CD1-CD2 3.53Å; L431-Y574 HydrophobicContact CD1-CE2 4.18Å; L431-Y574 HydrophobicContact CD1-CG 3.77Å; F492-Y574 HydrophobicContact CB-CD1 4.23Å; F492-Y574 AromaticContact CD1-CD1 3.55Å; F492-Y574 HydrophobicContact CD1-CD1 3.55Å; F492-Y574 HydrophobicContact CD1-CE1 4.31Å; F492-Y574 HydrophobicContact CD1-CG 4.19Å; F492-Y574 AromaticContact CD2-CD1 3.46Å; F492-Y574 HydrophobicContact CD2-CD1 3.46Å; F492-Y574 VanDerWaalsContact CD2-CD1 3.46Å; F492-Y574 AromaticContact CD2-CE1 3.54Å; F492-Y574 HydrophobicContact CD2-CE1 3.54Å; F492-Y574 AromaticContact CE1-CD1 3.57Å; F492-Y574 HydrophobicContact CE1-CD1 3.57Å; F492-Y574 HydrophobicContact CE1-CE1 4.05Å; F492-Y574 HydrophobicContact CE1-CG 4.12Å; F492-Y574 AromaticContact CE2-CD1 3.5Å; F492-Y574 HydrophobicContact CE2-CD1 3.5Å; F492-Y574 VanDerWaalsContact CE2-CD1 3.5Å; F492-Y574 AromaticContact CE2-CE1 3.22Å; F492-Y574 HydrophobicContact CE2-CE1 3.22Å; F492-Y574 AromaticContact CG-CD1 3.47Å; F492-Y574 HydrophobicContact CG-CD1 3.47Å; F492-Y574 VanDerWaalsContact CG-CD1 3.47Å; F492-Y574 HydrophobicContact CG-CE1 4.06Å; F492-Y574 HydrophobicContact CG-CG 4.47Å; F492-Y574 AromaticContact CZ-CD1 3.52Å; F492-Y574 HydrophobicContact CZ-CD1 3.52Å; F492-Y574 AromaticContact CZ-CE1 3.48Å; F492-Y574 HydrophobicContact CZ-CE1 3.48Å; F492-Y574 VanDerWaalsContact CZ-CE1 3.48Å; F492-Y574 HydrophobicContact CZ-CG 4.34Å; V570-Y574 PolarHBondContact O-N 3.39Å; F571-Y574 PolarHBondContact O-N 3.17Å; R572-Y574 VanDerWaalsContact C-N 3.29Å; R572-Y574 PolarHBondContact O-N 3.14Å; Y574-F576 PolarHBondContact O-N 2.88Å; Y574-A577 PolarHBondContact O-N 3.01Å; Y574-C578 WeakPolarHBondContact CE1-SG 3.34Å; Y574-C578 PolarHBondContact O-N 3.1Å
575	G	96.3	Very high	95.5	Very high	0 Å²	0	43 Å²	43	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-57.2	-47.1	175.1	0	0	0	0	0	112.8	V489 F571 R572 C578 L579	V489-G575 WeakPolarHBondContact CG2-O 3.49Å; F571-G575 PolarHBondContact O-N 3.38Å; R572-G575 PolarHBondContact O-N 3.39Å; R572-G575 VanDerWaalsContact O-N 3.17Å; G575-C578 WeakPolarHBondContact O-CB 3.27Å; G575-C578 PolarHBondContact O-N 2.88Å; G575-L579 PolarHBondContact O-N 3.43Å
576	F	96.5	Very high	95.4	Very high	114 Å²	114	44.7 Å²	44.7	50%	0.5	22%	0.224	S	C	.	.	H	α-helix	trans	-66.8	-38.1	175.1	-75.2	-65.9	0	0	0	112.8	L493 R572 S573 Y574 C578 L579 V580	L493-F576 HydrophobicContact CD2-CD2 4.25Å; L493-F576 HydrophobicContact CD2-CE2 3.95Å; L493-F576 HydrophobicContact CD2-CZ 4.23Å; R572-F576 WeakPolarHBondContact O-CD2 3.31Å; R572-F576 PolarHBondContact O-N 2.89Å; S573-F576 PolarHBondContact O-N 3.12Å; Y574-F576 PolarHBondContact O-N 2.88Å; F576-C578 VanDerWaalsContact C-N 3.34Å; F576-C578 PolarHBondContact O-N 3.35Å; F576-L579 WeakPolarHBondContact O-CB 3.47Å; F576-L579 PolarHBondContact O-N 2.8Å; F576-L579 VanDerWaalsContact O-N 3.13Å; F576-V580 WeakPolarHBondContact O-CG2 3.49Å; F576-V580 PolarHBondContact O-N 2.83Å
577	A	96.8	Very high	95.3	Very high	28 Å²	28	48 Å²	48	23%	0.231	24%	0.241	C	C	.	.	H	α-helix	trans	-64.9	-36.9	175.8	0	0	0	0	0	112.2	W424 S573 Y574 L579 V580 I581	W424-A577 HydrophobicContact CH2-CB 4.03Å; W424-A577 HydrophobicContact CZ2-CB 3.43Å; W424-A577 VanDerWaalsContact CZ2-CB 3.43Å; S573-A577 VanDerWaalsContact O-CB 3.26Å; S573-A577 WeakPolarHBondContact O-CB 3.43Å; S573-A577 PolarHBondContact O-N 2.88Å; Y574-A577 PolarHBondContact O-N 3.01Å; A577-L579 VanDerWaalsContact C-N 3.29Å; A577-L579 PolarHBondContact O-N 2.75Å; A577-V580 PolarHBondContact O-N 3.31Å; A577-I581 WeakPolarHBondContact O-CB 3.2Å; A577-I581 WeakPolarHBondContact O-CG1 3.46Å; A577-I581 PolarHBondContact O-N 2.78Å
578	C	96.5	Very high	94.9	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-59.8	-38.8	170.3	-80.1	0	0	0	0	112.3	W424 V489 Y574 G575 F576 I581 L582	W424-C578 PolarHBondContact NE1-SG 3.17Å; W424-C578 VanDerWaalsContact NE1-SG 3.4Å; V489-C578 HydrophobicContact CG2-CB 3.75Å; Y574-C578 WeakPolarHBondContact CE1-SG 3.34Å; Y574-C578 PolarHBondContact O-N 3.1Å; G575-C578 WeakPolarHBondContact O-CB 3.27Å; G575-C578 PolarHBondContact O-N 2.88Å; F576-C578 VanDerWaalsContact C-N 3.34Å; F576-C578 PolarHBondContact O-N 3.35Å; C578-I581 PolarHBondContact O-N 2.86Å; C578-L582 VanDerWaalsContact O-CB 3.28Å; C578-L582 WeakPolarHBondContact O-CB 3.31Å; C578-L582 PolarHBondContact O-N 2.77Å
579	L	96.6	Very high	94.4	Very high	72 Å²	72	47.5 Å²	47.5	38%	0.377	24%	0.244	S	C	.	.	H	α-helix	trans	-65.7	-43.9	176	-178	63.7	0	0	0	111.4	V489 G575 F576 A577 L582 V583	V489-L579 HydrophobicContact CG1-CB 4.46Å; V489-L579 HydrophobicContact CG2-CB 3.9Å; G575-L579 PolarHBondContact O-N 3.43Å; F576-L579 WeakPolarHBondContact O-CB 3.47Å; F576-L579 PolarHBondContact O-N 2.8Å; F576-L579 VanDerWaalsContact O-N 3.13Å; A577-L579 VanDerWaalsContact C-N 3.29Å; A577-L579 PolarHBondContact O-N 2.75Å; L579-L582 WeakPolarHBondContact O-CB 3.2Å; L579-L582 PolarHBondContact O-N 2.96Å; L579-V583 WeakPolarHBondContact O-CG2 3.46Å; L579-V583 PolarHBondContact O-N 2.97Å
580	V	97	Very high	94	Very high	87 Å²	87	50.1 Å²	50.1	53%	0.527	25%	0.249	S	C	.	.	H	α-helix	trans	-61.3	-46.5	176	173.8	0	0	0	0	110.8	F576 A577 L582 V583 L584	F576-V580 WeakPolarHBondContact O-CG2 3.49Å; F576-V580 PolarHBondContact O-N 2.83Å; A577-V580 PolarHBondContact O-N 3.31Å; V580-L582 VanDerWaalsContact C-N 3.33Å; V580-L582 PolarHBondContact O-N 3.37Å; V580-V583 PolarHBondContact O-N 3.12Å; V580-L584 HydrophobicContact CG1-CD1 3.97Å; V580-L584 HydrophobicContact CG1-CG 4.35Å; V580-L584 WeakPolarHBondContact O-CG 3.17Å; V580-L584 PolarHBondContact O-N 3.47Å
581	I	96	Very high	93.2	Very high	15 Å²	15	57.3 Å²	57.3	8%	0.077	28%	0.28	C	S	.	.	H	α-helix	trans	-65	-38	178.8	-71.2	169	0	0	0	111.4	F420 V421 W424 L485 A577 C578 L584 F585	F420-I581 HydrophobicContact CE1-CD1 4.1Å; F420-I581 HydrophobicContact CE1-CG1 4.31Å; V421-I581 HydrophobicContact CG2-CG2 4.03Å; W424-I581 HydrophobicContact CB-CD1 4.21Å; W424-I581 HydrophobicContact CD2-CD1 3.06Å; W424-I581 HydrophobicContact CE3-CD1 3.5Å; W424-I581 VanDerWaalsContact CE3-CD1 3.5Å; W424-I581 HydrophobicContact CG-CD1 3.36Å; W424-I581 HydrophobicContact CH2-CD1 4.14Å; W424-I581 HydrophobicContact CZ2-CD1 3.81Å; W424-I581 HydrophobicContact CZ3-CD1 4Å; L485-I581 HydrophobicContact CD1-CG2 4.21Å; L485-I581 HydrophobicContact CD2-CG2 4.38Å; A577-I581 WeakPolarHBondContact O-CB 3.2Å; A577-I581 WeakPolarHBondContact O-CG1 3.46Å; A577-I581 PolarHBondContact O-N 2.78Å; C578-I581 PolarHBondContact O-N 2.86Å; I581-L584 PolarHBondContact O-N 3.48Å; I581-F585 WeakPolarHBondContact O-CB 3.22Å; I581-F585 PolarHBondContact O-N 3.42Å
582	L	95.7	Very high	91.9	Very high	25 Å²	25	62.4 Å²	62.4	13%	0.131	31%	0.307	C	S	.	.	H	α-helix	trans	-58.6	-47.7	173.1	174.1	61.7	0	0	0	111.3	Y482 L485 L486 C578 L579 V580 F585 Y586	Y482-L582 HydrophobicContact CD1-CD1 3.65Å; Y482-L582 HydrophobicContact CG-CD1 4.03Å; L485-L582 HydrophobicContact CB-CB 4.14Å; L485-L582 HydrophobicContact CB-CD1 4.16Å; L485-L582 HydrophobicContact CD1-CB 4.1Å; L485-L582 HydrophobicContact CD1-CD1 4.18Å; L486-L582 HydrophobicContact CB-CD2 4.1Å; L486-L582 HydrophobicContact CD1-CD2 4.33Å; C578-L582 VanDerWaalsContact O-CB 3.28Å; C578-L582 WeakPolarHBondContact O-CB 3.31Å; C578-L582 PolarHBondContact O-N 2.77Å; L579-L582 WeakPolarHBondContact O-CB 3.2Å; L579-L582 PolarHBondContact O-N 2.96Å; V580-L582 VanDerWaalsContact C-N 3.33Å; V580-L582 PolarHBondContact O-N 3.37Å; L582-F585 PolarHBondContact O-N 3.18Å; L582-Y586 VanDerWaalsContact O-CB 3.27Å; L582-Y586 WeakPolarHBondContact O-CB 3.35Å; L582-Y586 PolarHBondContact O-N 3.29Å
583	V	95.2	Very high	90.5	Very high	74 Å²	74	61.5 Å²	61.5	45%	0.448	31%	0.305	S	S	.	.	H	α-helix	trans	-62.9	-48.8	177.8	173	0	0	0	0	110.6	L579 V580 F585 Y586 L587	L579-V583 WeakPolarHBondContact O-CG2 3.46Å; L579-V583 PolarHBondContact O-N 2.97Å; V580-V583 PolarHBondContact O-N 3.12Å; V583-F585 PolarHBondContact O-N 3.28Å; V583-Y586 PolarHBondContact O-N 3.23Å; V583-L587 HydrophobicContact CG1-CD1 3.85Å; V583-L587 HydrophobicContact CG1-CG 4.29Å; V583-L587 WeakPolarHBondContact O-CB 3.39Å; V583-L587 WeakPolarHBondContact O-CG 3.17Å; V583-L587 PolarHBondContact O-N 3.3Å
584	L	93.4	Very high	88.2	Confident	94 Å²	94	64.7 Å²	64.7	49%	0.492	33%	0.327	S	S	.	.	H	α-helix	trans	-60.1	-45.8	178.2	-69.5	175.1	0	0	0	111.9	V580 I581 Y586 L587 I588	V580-L584 HydrophobicContact CG1-CD1 3.97Å; V580-L584 HydrophobicContact CG1-CG 4.35Å; V580-L584 WeakPolarHBondContact O-CG 3.17Å; V580-L584 PolarHBondContact O-N 3.47Å; I581-L584 PolarHBondContact O-N 3.48Å; L584-Y586 VanDerWaalsContact C-N 3.33Å; L584-Y586 PolarHBondContact O-N 2.78Å; L584-L587 PolarHBondContact O-N 3.42Å; L584-I588 WeakPolarHBondContact O-CB 3.28Å; L584-I588 VanDerWaalsContact O-CG1 3.23Å; L584-I588 WeakPolarHBondContact O-CG1 3.43Å; L584-I588 PolarHBondContact O-N 3.19Å
585	F	92.4	Very high	85.5	Confident	5 Å²	5	70.9 Å²	70.9	2%	0.022	36%	0.356	C	S	.	.	H	α-helix	trans	-64.9	-38.7	178.9	-173.4	-130.1	0	0	0	111.6	A417 V421 T478 L481 Y482 I581 L582 V583 N589	A417-F585 HydrophobicContact CB-CD2 4.19Å; A417-F585 HydrophobicContact CB-CE2 4.18Å; V421-F585 HydrophobicContact CG2-CB 4.02Å; V421-F585 HydrophobicContact CG2-CD1 3.91Å; V421-F585 HydrophobicContact CG2-CD2 3.74Å; V421-F585 HydrophobicContact CG2-CE1 4.33Å; V421-F585 HydrophobicContact CG2-CE2 4.14Å; V421-F585 HydrophobicContact CG2-CG 3.63Å; V421-F585 HydrophobicContact CG2-CZ 4.43Å; T478-F585 HydrophobicContact CG2-CE1 3.86Å; T478-F585 HydrophobicContact CG2-CZ 3.86Å; L481-F585 HydrophobicContact CB-CE1 4.08Å; L481-F585 HydrophobicContact CD2-CE1 4.2Å; L481-F585 HydrophobicContact CD2-CZ 4.28Å; Y482-F585 AromaticContact CD1-CD1 3.66Å; Y482-F585 HydrophobicContact CD1-CD1 3.66Å; Y482-F585 HydrophobicContact CD1-CE1 4.05Å; Y482-F585 HydrophobicContact CE1-CB 4.49Å; Y482-F585 AromaticContact CE1-CD1 3.26Å; Y482-F585 HydrophobicContact CE1-CD1 3.26Å; Y482-F585 AromaticContact CE1-CE1 3.65Å; Y482-F585 HydrophobicContact CE1-CE1 3.65Å; Y482-F585 HydrophobicContact CE1-CG 4.07Å; I581-F585 WeakPolarHBondContact O-CB 3.22Å; I581-F585 PolarHBondContact O-N 3.42Å; L582-F585 PolarHBondContact O-N 3.18Å; V583-F585 PolarHBondContact O-N 3.28Å; F585-N589 VanDerWaalsContact CD2-ND2 3.3Å; F585-N589 WeakPolarHBondContact CD2-ND2 3.45Å; F585-N589 WeakPolarHBondContact CE2-ND2 3.07Å; F585-N589 VanDerWaalsContact CZ-ND2 3.33Å; F585-N589 WeakPolarHBondContact CZ-ND2 3.4Å; F585-N589 WeakPolarHBondContact O-CB 3.38Å; F585-N589 PolarHBondContact O-N 3.39Å; F585-N589 PolarHBondContact O-ND2 3.47Å
586	Y	91.9	Very high	82.9	Confident	103 Å²	103	75.6 Å²	75.6	40%	0.404	38%	0.379	S	S	.	.	H	α-helix	trans	-62.3	-46.5	172.5	176.6	-96.9	0	0	0	112	Y482 L582 V583 L584 N589 R590	Y482-Y586 HydrophobicContact CE2-CD2 4.19Å; L582-Y586 VanDerWaalsContact O-CB 3.27Å; L582-Y586 WeakPolarHBondContact O-CB 3.35Å; L582-Y586 PolarHBondContact O-N 3.29Å; V583-Y586 PolarHBondContact O-N 3.23Å; L584-Y586 VanDerWaalsContact C-N 3.33Å; L584-Y586 PolarHBondContact O-N 2.78Å; Y586-N589 PolarHBondContact O-N 2.68Å; Y586-R590 VanDerWaalsContact O-CB 3.25Å; Y586-R590 WeakPolarHBondContact O-CB 3Å; Y586-R590 PolarHBondContact O-N 2.85Å; Y586-R590 PolarHBondContact OH-NH1 2.91Å
587	L	90.9	Very high	80.3	Confident	69 Å²	69	74.2 Å²	74.2	36%	0.361	38%	0.379	S	S	.	.	H	α-helix	trans	-64	-43.9	178.7	-67.1	172.3	0	0	0	111.5	V583 L584 N589 R590 F591	V583-L587 HydrophobicContact CG1-CD1 3.85Å; V583-L587 HydrophobicContact CG1-CG 4.29Å; V583-L587 WeakPolarHBondContact O-CB 3.39Å; V583-L587 WeakPolarHBondContact O-CG 3.17Å; V583-L587 PolarHBondContact O-N 3.3Å; L584-L587 PolarHBondContact O-N 3.42Å; L587-N589 PolarHBondContact O-N 3.21Å; L587-R590 PolarHBondContact O-N 3.17Å; L587-F591 HydrophobicContact CB-CD2 4.26Å; L587-F591 HydrophobicContact CD2-CD2 4.05Å; L587-F591 HydrophobicContact CD2-CE2 3.61Å; L587-F591 WeakPolarHBondContact O-CB 3.3Å; L587-F591 WeakPolarHBondContact O-CD2 3.31Å; L587-F591 PolarHBondContact O-N 3.22Å
588	I	87.4	Confident	77.1	Confident	54 Å²	54	82.7 Å²	82.7	28%	0.277	41%	0.405	S	S	.	.	H	α-helix	trans	-59	-49.4	176.9	-71.6	165.2	0	0	0	110.3	A417 L584 R590 L592 F593	A417-I588 HydrophobicContact CB-CG2 4.2Å; L584-I588 WeakPolarHBondContact O-CB 3.28Å; L584-I588 VanDerWaalsContact O-CG1 3.23Å; L584-I588 WeakPolarHBondContact O-CG1 3.43Å; L584-I588 PolarHBondContact O-N 3.19Å; I588-R590 VanDerWaalsContact C-N 3.31Å; I588-R590 PolarHBondContact O-N 3.27Å; I588-L592 HydrophobicContact CB-CD1 4.35Å; I588-L592 HydrophobicContact CG1-CD1 4.29Å; I588-L592 HydrophobicContact CG2-CD1 4.27Å; I588-L592 WeakPolarHBondContact O-CB 3.32Å; I588-L592 PolarHBondContact O-N 2.96Å; I588-F593 HydrophobicContact CG2-CD2 4.22Å; I588-F593 HydrophobicContact CG2-CE2 3.71Å
589	N	84	Confident	74.2	Confident	23 Å²	23	88.4 Å²	88.4	12%	0.123	43%	0.43	C	S	.	.	H	α-helix	trans	-67.4	-30.2	178.8	-77	-66	0	0	0	113.2	Y482 F585 Y586 L587 F593	Y482-N589 VanDerWaalsContact OH-CB 3.26Å; Y482-N589 WeakPolarHBondContact OH-CB 3.48Å; Y482-N589 PolarHBondContact OH-ND2 2.85Å; F585-N589 VanDerWaalsContact CD2-ND2 3.3Å; F585-N589 WeakPolarHBondContact CD2-ND2 3.45Å; F585-N589 WeakPolarHBondContact CE2-ND2 3.07Å; F585-N589 VanDerWaalsContact CZ-ND2 3.33Å; F585-N589 WeakPolarHBondContact CZ-ND2 3.4Å; F585-N589 WeakPolarHBondContact O-CB 3.38Å; F585-N589 PolarHBondContact O-N 3.39Å; F585-N589 PolarHBondContact O-ND2 3.47Å; Y586-N589 PolarHBondContact O-N 2.68Å; L587-N589 PolarHBondContact O-N 3.21Å; N589-F593 VanDerWaalsContact O-O 3.12Å
590	R	84.5	Confident	71.1	Confident	157 Å²	157	90.2 Å²	90.2	59%	0.592	44%	0.441	S	S	*	.	H	α-helix	trans	-78.3	-40.9	179	-177.6	173.1	178.3	142.3	1	112.9	Y586 L587 I588	Y586-R590 VanDerWaalsContact O-CB 3.25Å; Y586-R590 WeakPolarHBondContact O-CB 3Å; Y586-R590 PolarHBondContact O-N 2.85Å; Y586-R590 PolarHBondContact OH-NH1 2.91Å; L587-R590 PolarHBondContact O-N 3.17Å; I588-R590 VanDerWaalsContact C-N 3.31Å; I588-R590 PolarHBondContact O-N 3.27Å
591	F	80.7	Confident	67.9	Low	153 Å²	153	90.8 Å²	90.8	67%	0.671	45%	0.446	S	S	*	.	H	α-helix	trans	-100.5	-37.2	-169.8	-73	-70	0	0	0	114.2	L587	L587-F591 HydrophobicContact CB-CD2 4.26Å; L587-F591 HydrophobicContact CD2-CD2 4.05Å; L587-F591 HydrophobicContact CD2-CE2 3.61Å; L587-F591 WeakPolarHBondContact O-CB 3.3Å; L587-F591 WeakPolarHBondContact O-CD2 3.31Å; L587-F591 PolarHBondContact O-N 3.22Å
592	L	69.6	Low	64.8	Low	108 Å²	108	93.4 Å²	93.4	57%	0.565	47%	0.47	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85	-19.2	-179.2	-77.5	99.5	0	0	0	112.9	I588	I588-L592 HydrophobicContact CB-CD1 4.35Å; I588-L592 HydrophobicContact CG1-CD1 4.29Å; I588-L592 HydrophobicContact CG2-CD1 4.27Å; I588-L592 WeakPolarHBondContact O-CB 3.32Å; I588-L592 PolarHBondContact O-N 2.96Å
593	F	64.9	Low	62.1	Low	55 Å²	55	95.5 Å²	95.5	24%	0.241	49%	0.491	C	S	.	.			trans	-138	80.6	-168.3	-53.4	-63.7	0	0	0	112	P413 H414 I588 N589	P413-F593 HydrophobicContact CB-CZ 3.97Å; P413-F593 HydrophobicContact CG-CE1 4.3Å; P413-F593 HydrophobicContact CG-CZ 3.87Å; H414-F593 HydrophobicContact CB-CD1 4.33Å; H414-F593 HydrophobicContact CB-CD2 4.22Å; H414-F593 HydrophobicContact CB-CE1 3.94Å; H414-F593 HydrophobicContact CB-CE2 3.8Å; H414-F593 HydrophobicContact CB-CG 4.48Å; H414-F593 HydrophobicContact CB-CZ 3.67Å; H414-F593 AromaticContact ND1-CD2 3.59Å; H414-F593 AromaticContact ND1-CG 3.63Å; I588-F593 HydrophobicContact CG2-CD2 4.22Å; I588-F593 HydrophobicContact CG2-CE2 3.71Å; N589-F593 VanDerWaalsContact O-O 3.12Å
594	S	48	Very low	59.3	Low	115 Å²	115	96.5 Å²	96.5	80%	0.804	50%	0.497	S	S	*	.			trans	-84.6	-20.6	166.8	76.3	0	0	0	0	113.1	Q596	S594-Q596 PolarHBondContact O-N 2.8Å
595	E	41.4	Very low	56.3	Low	137 Å²	137	96.8 Å²	96.8	64%	0.64	51%	0.507	S	S	*	.	S	Bend	trans	-87.6	102.2	172.1	-83.7	-167.9	131	0	0	110.3	R598	E595-R598 IonicContact OE1-CZ 2.87Å; E595-R598 IonicContact OE1-NE 3.83Å; E595-R598 IonicContact OE1-NH2 3.52Å; E595-R598 PolarHBondContact OE1-NH2 3.48Å
596	Q	42.2	Very low	53.4	Low	100 Å²	100	102.3 Å²	102.3	47%	0.467	53%	0.533	S	S	.	.			trans	-56.5	138.2	167.4	-60.7	178.6	-64.4	0	0	108.7	S594 R598 Y638	S594-Q596 PolarHBondContact O-N 2.8Å; Q596-R598 PolarHBondContact O-N 3.44Å; Q596-Y638 PolarHBondContact NE2-O 3.02Å
597	V	41.6	Very low	50.5	Low	85 Å²	85	101.5 Å²	101.5	52%	0.515	54%	0.54	S	S	.	.			trans	-34.8	106.2	176.3	177.1	0	0	0	0	110.3	F599	V597-F599 PolarHBondContact O-N 3.09Å
598	R	30	Very low	47.9	Very low	205 Å²	205	103.9 Å²	103.9	77%	0.774	55%	0.549	S	S	*	.			trans	-64.5	104.5	169.6	-75.3	-169.6	-166.8	-171.9	6.1	106.4	E595 Q596 N600	E595-R598 IonicContact OE1-CZ 2.87Å; E595-R598 IonicContact OE1-NE 3.83Å; E595-R598 IonicContact OE1-NH2 3.52Å; E595-R598 PolarHBondContact OE1-NH2 3.48Å; Q596-R598 PolarHBondContact O-N 3.44Å; R598-N600 PolarHBondContact O-N 2.91Å
599	F	33.5	Very low	45.4	Very low	120 Å²	120	107.2 Å²	107.2	53%	0.526	57%	0.572	S	S	.	*			trans	-52.7	125.3	170.6	-154.9	-96.8	0	0	0	107.7	V597 P601 V604	V597-F599 PolarHBondContact O-N 3.09Å; F599-P601 WeakPolarHBondContact O-CD 3.46Å; F599-V604 HydrophobicContact CD1-CG2 4.34Å; F599-V604 HydrophobicContact CE1-CG2 3.44Å; F599-V604 VanDerWaalsContact CE1-CG2 3.44Å; F599-V604 HydrophobicContact CZ-CG2 4.26Å
600	N	32.1	Very low	43.1	Very low	111 Å²	111	108.5 Å²	108.5	59%	0.594	58%	0.581	S	S	*	*			trans	-81.8	106.6	171.1	-168.7	2.9	0	0	0	106.8	R598 A602 A603	R598-N600 PolarHBondContact O-N 2.91Å; N600-A602 PolarHBondContact O-N 3.2Å; N600-A603 WeakPolarHBondContact O-CB 3.39Å; N600-A603 PolarHBondContact O-N 3.2Å
601	P	31.3	Very low	40.8	Very low	99 Å²	99	103.6 Å²	103.6	64%	0.643	57%	0.566	S	S	*	*	G	3₁₀ helix	trans	-59.8	-20	-178.8	23.4	-32.6	0	0	0	112.5	F599 A603 V604	F599-P601 WeakPolarHBondContact O-CD 3.46Å; P601-A603 PolarHBondContact O-N 3.29Å; P601-A603 VanDerWaalsContact O-N 3.12Å; P601-V604 WeakPolarHBondContact O-CB 3.46Å; P601-V604 PolarHBondContact O-N 2.87Å; P601-V604 VanDerWaalsContact O-N 3.11Å
602	A	30.2	Very low	38.6	Very low	69 Å²	69	97.4 Å²	97.4	57%	0.57	54%	0.543	S	S	*	.	G	3₁₀ helix	trans	-64.4	-9.9	173.1	0	0	0	0	0	114.6	N600 S605	N600-A602 PolarHBondContact O-N 3.2Å; A602-S605 PolarHBondContact O-OG 3.49Å
603	A	38.1	Very low	36.9	Very low	69 Å²	69	94.1 Å²	94.1	57%	0.57	53%	0.529	S	S	*	.	G	3₁₀ helix	trans	-88.9	-2.5	174.2	0	0	0	0	0	113.7	N600 P601	N600-A603 WeakPolarHBondContact O-CB 3.39Å; N600-A603 PolarHBondContact O-N 3.2Å; P601-A603 PolarHBondContact O-N 3.29Å; P601-A603 VanDerWaalsContact O-N 3.12Å
604	V	37.1	Very low	35.6	Very low	96 Å²	96	93.6 Å²	93.6	58%	0.582	53%	0.527	S	S	*	.	S	Bend	trans	-92.4	-16.5	-177.7	-174.3	0	0	0	0	112.5	F599 P601 E606	F599-V604 HydrophobicContact CD1-CG2 4.34Å; F599-V604 HydrophobicContact CE1-CG2 3.44Å; F599-V604 VanDerWaalsContact CE1-CG2 3.44Å; F599-V604 HydrophobicContact CZ-CG2 4.26Å; P601-V604 WeakPolarHBondContact O-CB 3.46Å; P601-V604 PolarHBondContact O-N 2.87Å; P601-V604 VanDerWaalsContact O-N 3.11Å; V604-E606 PolarHBondContact O-N 2.77Å; V604-E606 VanDerWaalsContact O-N 3.17Å
605	S	30	Very low	34.9	Very low	100 Å²	100	88.4 Å²	88.4	70%	0.699	49%	0.491	S	S	*	.	S	Bend	trans	-76.2	3.3	-175.2	55.9	0	0	0	0	114.9	A602	A602-S605 PolarHBondContact O-OG 3.49Å
606	E	32.2	Very low	34.4	Very low	121 Å²	121	84.8 Å²	84.8	57%	0.565	48%	0.476	S	S	*	.	S	Bend	trans	-115	114.6	173.3	-78.9	-172.7	170.5	0	0	111.7	V604 Q608	V604-E606 PolarHBondContact O-N 2.77Å; V604-E606 VanDerWaalsContact O-N 3.17Å; E606-Q608 VanDerWaalsContact C-N 3.28Å; E606-Q608 PolarHBondContact O-N 3.32Å
607	P	30.9	Very low	33.8	Very low	86 Å²	86	83.9 Å²	83.9	56%	0.558	48%	0.478	S	S	*	.			trans	-76.5	78.2	175.5	32	-32.7	0	0	0	109.9
608	Q	36	Very low	33.7	Very low	118 Å²	118	82.6 Å²	82.6	55%	0.551	47%	0.467	S	S	*	.			trans	-110.4	121.9	173.5	-70.5	-173.9	-2.2	0	0	111	E606 T610	E606-Q608 VanDerWaalsContact C-N 3.28Å; E606-Q608 PolarHBondContact O-N 3.32Å; Q608-T610 PolarHBondContact O-N 3.33Å
609	T	35.4	Very low	34.1	Very low	125 Å²	125	78.6 Å²	78.6	77%	0.767	46%	0.461	S	S	*	.			trans	-51.2	94	176.3	42.7	0	0	0	0	111.5	L611	T609-L611 PolarHBondContact O-N 2.76Å
610	T	36	Very low	34.2	Very low	50 Å²	50	77.1 Å²	77.1	31%	0.307	46%	0.462	S	S	.	.			trans	-82.4	109.6	174.3	45.7	0	0	0	0	109.2	Q608 M618	Q608-T610 PolarHBondContact O-N 3.33Å; T610-M618 WeakPolarHBondContact O-CB 3.19Å; T610-M618 PolarHBondContact O-N 2.84Å
611	L	34.6	Very low	34.2	Very low	54 Å²	54	77.4 Å²	77.4	28%	0.283	47%	0.47	S	S	.	.	B	Isolated β-bridge	trans	-93.1	133.2	174.1	-65.8	131.1	0	0	0	108.8	P288 E289 T609	P288-L611 HydrophobicContact CB-CD1 3.75Å; P288-L611 HydrophobicContact CB-CD2 4.27Å; P288-L611 HydrophobicContact CG-CD1 3.37Å; P288-L611 HydrophobicContact CG-CD2 4.07Å; P288-L611 HydrophobicContact CG-CG 4.33Å; E289-L611 HydrophobicContact CB-CD2 3.45Å; E289-L611 VanDerWaalsContact CB-CD2 3.45Å; T609-L611 PolarHBondContact O-N 2.76Å
612	A	35.6	Very low	34.4	Very low	23 Å²	23	79.5 Å²	79.5	19%	0.19	47%	0.469	C	S	.	.			trans	-59.5	148.5	158.3	0	0	0	0	0	108.4	H614 G615 I616	A612-H614 PolarHBondContact O-N 2.76Å; A612-G615 PolarHBondContact O-N 3.13Å; A612-I616 HydrophobicContact CB-CB 4.26Å; A612-I616 PolarHBondContact N-O 3.31Å
613	P	34.2	Very low	34.5	Very low	39 Å²	39	80.8 Å²	80.8	25%	0.253	47%	0.472	S	S	.	.	T	Hydrogen-bonded Turn	trans	-63.6	3.7	-179.2	15.9	-22.9	0	0	0	115.6	T523	T523-P613 HydrophobicContact CG2-CG 3.54Å
614	H	38	Very low	34.4	Very low	44 Å²	44	86.3 Å²	86.3	20%	0.204	49%	0.486	C	S	.	.	T	Hydrogen-bonded Turn	trans	-110.8	21.9	167.9	-59.7	-54.8	0	0	0	112.8	G292 Y465 W519 A612 I616	G292-H614 WeakPolarHBondContact CA-O 3.24Å; G292-H614 PolarHBondContact N-O 3.22Å; Y465-H614 AromaticContact CE1-CD2 3.32Å; Y465-H614 WeakPolarHBondContact CE1-CD2 3.39Å; Y465-H614 AromaticContact CE1-NE2 3.37Å; Y465-H614 WeakPolarHBondContact CE1-NE2 3.23Å; Y465-H614 AromaticContact CZ-CD2 3.88Å; Y465-H614 AromaticContact CZ-NE2 3.54Å; Y465-H614 PolarHBondContact OH-CE1 3.21Å; Y465-H614 PolarHBondContact OH-NE2 2.75Å; Y465-H614 VanDerWaalsContact OH-NE2 3.13Å; W519-H614 AromaticContact CD1-CE1 3.94Å; W519-H614 AromaticContact CD1-NE2 3.16Å; W519-H614 AromaticContact NE1-CE1 3.78Å; W519-H614 AromaticContact NE1-NE2 3.33Å; W519-H614 PolarHBondContact NE1-NE2 3.33Å; A612-H614 PolarHBondContact O-N 2.76Å; H614-I616 VanDerWaalsContact C-N 3.33Å; H614-I616 PolarHBondContact O-N 3.28Å
615	G	32.9	Very low	34.3	Very low	5 Å²	5	91.1 Å²	91.1	5%	0.052	50%	0.499	C	S	.	.	S	Bend	trans	72.3	10.6	178.7	0	0	0	0	0	115.5	E289 A612 P617	E289-G615 CarbonylContact C-O 3.53Å; E289-G615 WeakPolarHBondContact CA-O 3.1Å; E289-G615 WeakPolarHBondContact CB-O 3.18Å; E289-G615 CarbonylContact O-C 3.58Å; E289-G615 VanDerWaalsContact O-C 3.23Å; E289-G615 WeakPolarHBondContact O-CA 3.41Å; A612-G615 PolarHBondContact O-N 3.13Å; G615-P617 WeakPolarHBondContact O-CD 3.47Å
616	I	30.1	Very low	34.8	Very low	62 Å²	62	88.4 Å²	88.4	32%	0.318	48%	0.48	S	S	.	.			trans	-80	124.2	177.5	-52.7	176.5	0	0	0	109	A612 H614	A612-I616 HydrophobicContact CB-CB 4.26Å; A612-I616 PolarHBondContact N-O 3.31Å; H614-I616 VanDerWaalsContact C-N 3.33Å; H614-I616 PolarHBondContact O-N 3.28Å
617	P	30.6	Very low	35	Very low	81 Å²	81	89.8 Å²	89.8	53%	0.526	49%	0.486	S	S	.	.	B	Isolated β-bridge	trans	-73.6	129	179	27.1	-26.5	0	0	0	110	E289 G615	E289-P617 HydrophobicContact CB-CB 4.19Å; E289-P617 HydrophobicContact CB-CG 4.12Å; E289-P617 HydrophobicContact CG-CG 4.38Å; G615-P617 WeakPolarHBondContact O-CD 3.47Å
618	M	38.9	Very low	35.1	Very low	57 Å²	57	94.7 Å²	94.7	28%	0.281	50%	0.499	S	S	.	.			trans	-92.3	-3.2	-174.2	-77.5	-77.4	-62.3	0	0	115.1	F469 T610	F469-M618 HydrophobicContact CD2-SD 3.79Å; F469-M618 HydrophobicContact CE2-CE 4.23Å; F469-M618 HydrophobicContact CE2-SD 3.64Å; T610-M618 WeakPolarHBondContact O-CB 3.19Å; T610-M618 PolarHBondContact O-N 2.84Å
619	N	38.9	Very low	34.9	Very low	121 Å²	121	95.5 Å²	95.5	65%	0.647	51%	0.506	S	S	*	.			trans	-124.9	122.3	-174.6	-89.8	-6.4	0	0	0	113.9
620	V	35.2	Very low	34.9	Very low	89 Å²	89	96.5 Å²	96.5	54%	0.539	51%	0.506	S	S	.	.	P	Polyproline II helix	trans	-98	133.2	154.4	-169.7	0	0	0	0	106	F622	V620-F622 PolarHBondContact O-N 2.77Å
621	P	32.8	Very low	34.7	Very low	118 Å²	118	101.2 Å²	101.2	77%	0.766	53%	0.53	S	S	*	.	P	Polyproline II helix	trans	-62.3	128.8	-177	-15.8	27.8	0	0	0	111.3
622	F	34.8	Very low	34.5	Very low	143 Å²	143	101.9 Å²	101.9	63%	0.627	54%	0.543	S	S	*	.	P	Polyproline II helix	trans	-73.8	133	170.1	-83.1	-84	0	0	0	110	V620 Y651	V620-F622 PolarHBondContact O-N 2.77Å; F622-Y651 HydrophobicContact CE1-CE1 4.01Å
623	P	31.4	Very low	34.1	Very low	96 Å²	96	108.9 Å²	108.9	62%	0.623	58%	0.577	S	S	*	*	P	Polyproline II helix	trans	-70.5	138.5	172.1	-12.7	26.9	0	0	0	111.4	K625 S626	P623-K625 PolarHBondContact O-N 3.26Å; P623-S626 PolarHBondContact O-N 3.28Å; P623-S626 VanDerWaalsContact O-N 3.12Å; P623-S626 PolarHBondContact O-OG 2.66Å; P623-S626 VanDerWaalsContact O-OG 3.04Å
624	E	36.4	Very low	33.8	Very low	184 Å²	184	111.1 Å²	111.1	86%	0.86	60%	0.599	S	S	*	*	G	3₁₀ helix	trans	-49.3	-11.6	179.6	-151.4	176.1	-168.2	0	0	115.9
625	K	35.8	Very low	33.2	Very low	197 Å²	197	115.1 Å²	115.1	86%	0.857	63%	0.632	S	S	*	*	G	3₁₀ helix	trans	-85.8	-3.5	178.1	-73.8	-177.7	178	176.2	0	115.1	P623	P623-K625 PolarHBondContact O-N 3.26Å
626	S	39.6	Very low	32.9	Very low	44 Å²	44	118 Å²	118	31%	0.308	66%	0.661	S	S	.	*	G	3₁₀ helix	trans	-86.3	-6.4	178.5	53	0	0	0	0	114.9	P623 K628 L629	P623-S626 PolarHBondContact O-N 3.28Å; P623-S626 VanDerWaalsContact O-N 3.12Å; P623-S626 PolarHBondContact O-OG 2.66Å; P623-S626 VanDerWaalsContact O-OG 3.04Å; S626-K628 PolarHBondContact O-N 3.15Å; S626-L629 PolarHBondContact O-N 3.32Å; S626-L629 VanDerWaalsContact O-N 3.16Å
627	E	37.2	Very low	32.7	Very low	149 Å²	149	119.4 Å²	119.4	70%	0.696	68%	0.677	S	S	*	*	G	3₁₀ helix	trans	-62.9	-25.2	178.1	-127	176.8	178.1	0	0	112.8	L629	E627-L629 VanDerWaalsContact C-N 3.29Å; E627-L629 PolarHBondContact O-N 2.85Å
628	K	33.7	Very low	32.5	Very low	190 Å²	190	123.4 Å²	123.4	83%	0.826	68%	0.682	S	S	*	*	G	3₁₀ helix	trans	-80	-0.6	177.3	-68.4	-171.5	175.9	-175.4	0	115.3	S626	S626-K628 PolarHBondContact O-N 3.15Å
629	L	30.2	Very low	32.2	Very low	134 Å²	134	122.3 Å²	122.3	70%	0.702	69%	0.686	S	S	*	*	G	3₁₀ helix	trans	-99.8	-5.1	177.1	-87.4	153.9	0	0	0	113.1	S626 E627	S626-L629 PolarHBondContact O-N 3.32Å; S626-L629 VanDerWaalsContact O-N 3.16Å; E627-L629 VanDerWaalsContact C-N 3.29Å; E627-L629 PolarHBondContact O-N 2.85Å
630	L	36	Very low	31.7	Very low	146 Å²	146	120.5 Å²	120.5	76%	0.764	69%	0.688	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.9	-7.6	178.3	-71.1	164.4	0	0	0	113.5
631	D	32.5	Very low	31.7	Very low	150 Å²	150	120.9 Å²	120.9	80%	0.802	69%	0.69	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.9	3.1	175.7	-74.9	-28.6	0	0	0	113.7	D633	D631-D633 PolarHBondContact O-N 2.82Å
632	A	29.6	Very low	31.7	Very low	67 Å²	67	119.9 Å²	119.9	55%	0.554	68%	0.679	S	S	*	*	S	Bend	trans	-91.7	102.7	-179.8	0	0	0	0	0	111.2	A634	A632-A634 PolarHBondContact O-N 2.8Å
633	D	26.9	Very low	31.9	Very low	170 Å²	170	119.3 Å²	119.3	91%	0.909	69%	0.689	S	S	*	*			trans	-40.7	82.4	170.9	-151.5	8.6	0	0	0	113.8	D631	D631-D633 PolarHBondContact O-N 2.82Å
634	A	28.7	Very low	32.2	Very low	87 Å²	87	117.8 Å²	117.8	72%	0.719	68%	0.678	S	S	*	*			trans	-122.1	84.5	178.4	0	0	0	0	0	110.6	A632 G636	A632-A634 PolarHBondContact O-N 2.8Å; A634-G636 VanDerWaalsContact C-N 3.3Å; A634-G636 PolarHBondContact O-N 3.48Å
635	S	25.4	Very low	32.3	Very low	127 Å²	127	115.3 Å²	115.3	89%	0.888	67%	0.667	S	S	*	*			trans	-59.9	84.9	162.3	45.2	0	0	0	0	110.7
636	G	25.8	Very low	32.6	Very low	65 Å²	65	109.3 Å²	109.3	67%	0.67	65%	0.653	S	S	*	*	S	Bend	trans	-175.3	105.6	179.3	0	0	0	0	0	115.5	A634	A634-G636 VanDerWaalsContact C-N 3.3Å; A634-G636 PolarHBondContact O-N 3.48Å
637	S	26	Very low	32.6	Very low	93 Å²	93	107.9 Å²	107.9	65%	0.65	65%	0.645	S	S	*	*			trans	40.1	92.5	154.7	-141.5	0	0	0	0	117.4	G639	S637-G639 PolarHBondContact O-N 3.26Å
638	Y	26.1	Very low	32.6	Very low	164 Å²	164	105.6 Å²	105.6	64%	0.643	63%	0.63	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.3	120.1	167.1	-132.8	-101.8	0	0	0	110.1	Q596	Q596-Y638 PolarHBondContact NE2-O 3.02Å
639	G	33.8	Very low	33.2	Very low	35 Å²	35	99 Å²	99	36%	0.361	60%	0.604	S	S	.	*	T	Hydrogen-bonded Turn	trans	130.6	5.9	172.9	0	0	0	0	0	117.5	S637	S637-G639 PolarHBondContact O-N 3.26Å
640	A	27	Very low	33.7	Very low	82 Å²	82	101.9 Å²	101.9	68%	0.678	61%	0.606	S	S	*	*			trans	-115.4	106.9	169.9	0	0	0	0	0	109.8
641	V	36.5	Very low	33.8	Very low	97 Å²	97	100.9 Å²	100.9	59%	0.588	59%	0.593	S	S	*	*			trans	-63.4	134.9	160.5	-177.7	0	0	0	0	107	P643	V641-P643 WeakPolarHBondContact O-CD 2.8Å; V641-P643 VanDerWaalsContact O-N 3.08Å
642	D	32.1	Very low	34.5	Very low	98 Å²	98	97.4 Å²	97.4	52%	0.524	58%	0.577	S	S	.	*			trans	-41.5	116.3	174.1	-179	7.8	0	0	0	110.1	T644 A647	D642-T644 VanDerWaalsContact CG-OG1 3.24Å; D642-T644 PolarHBondContact O-N 3.21Å; D642-T644 VanDerWaalsContact OD1-CG2 3.29Å; D642-T644 WeakPolarHBondContact OD1-CG2 3.21Å; D642-T644 PolarHBondContact OD1-N 3.26Å; D642-T644 PolarHBondContact OD1-OG1 3.08Å; D642-T644 PolarHBondContact OD2-OG1 3.14Å; D642-A647 HydrophobicContact CB-CB 4.46Å
643	P	38.2	Very low	35	Very low	131 Å²	131	101.4 Å²	101.4	85%	0.851	58%	0.582	S	S	*	*			trans	-73.9	8.2	-173	30.2	-35.1	0	0	0	113.3	V641	V641-P643 WeakPolarHBondContact O-CD 2.8Å; V641-P643 VanDerWaalsContact O-N 3.08Å
644	T	38	Very low	35.5	Very low	64 Å²	64	99.1 Å²	99.1	39%	0.393	57%	0.565	S	S	.	*			trans	-68.7	138.2	179.5	57.4	0	0	0	0	112.4	D642 A646 A647 Y648	D642-T644 VanDerWaalsContact CG-OG1 3.24Å; D642-T644 PolarHBondContact O-N 3.21Å; D642-T644 VanDerWaalsContact OD1-CG2 3.29Å; D642-T644 WeakPolarHBondContact OD1-CG2 3.21Å; D642-T644 PolarHBondContact OD1-N 3.26Å; D642-T644 PolarHBondContact OD1-OG1 3.08Å; D642-T644 PolarHBondContact OD2-OG1 3.14Å; T644-A646 PolarHBondContact O-N 2.79Å; T644-A646 VanDerWaalsContact O-N 3.11Å; T644-A647 WeakPolarHBondContact O-CB 3.29Å; T644-A647 PolarHBondContact O-N 3.04Å; T644-Y648 PolarHBondContact O-N 3.45Å
645	Q	40.3	Very low	36	Very low	132 Å²	132	98.1 Å²	98.1	62%	0.617	55%	0.551	S	S	*	*	H	α-helix	trans	-54.2	-29.9	172.5	-168.5	69.6	24.7	0	0	111.8	Y648 D649	Q645-Y648 PolarHBondContact O-N 3.02Å; Q645-D649 PolarHBondContact O-N 2.66Å
646	A	40.1	Very low	36.5	Very low	70 Å²	70	102.8 Å²	102.8	58%	0.579	55%	0.551	S	S	*	*	H	α-helix	trans	-64	-36.6	175.7	0	0	0	0	0	113.4	T644 R650	T644-A646 PolarHBondContact O-N 2.79Å; T644-A646 VanDerWaalsContact O-N 3.11Å; A646-R650 PolarHBondContact O-N 3.22Å
647	A	40.4	Very low	36.9	Very low	15 Å²	15	103.9 Å²	103.9	12%	0.124	55%	0.549	C	S	.	.	H	α-helix	trans	-69.3	-42.5	173.6	0	0	0	0	0	110.8	D642 T644 R650 Y651	D642-A647 HydrophobicContact CB-CB 4.46Å; T644-A647 WeakPolarHBondContact O-CB 3.29Å; T644-A647 PolarHBondContact O-N 3.04Å; A647-R650 PolarHBondContact O-N 3.2Å; A647-Y651 WeakPolarHBondContact O-CD2 3.47Å; A647-Y651 PolarHBondContact O-N 2.98Å
648	Y	37.9	Very low	37.2	Very low	100 Å²	100	107.6 Å²	107.6	39%	0.392	55%	0.553	S	S	.	*	H	α-helix	trans	-64.3	-43.3	178.1	-166.7	-89	0	0	0	113.1	R470 T644 Q645 R650 Y651 V652	R470-Y648 PolarHBondContact NH2-OH 2.72Å; T644-Y648 PolarHBondContact O-N 3.45Å; Q645-Y648 PolarHBondContact O-N 3.02Å; Y648-R650 VanDerWaalsContact C-N 3.3Å; Y648-R650 PolarHBondContact O-N 3.13Å; Y648-Y651 PolarHBondContact O-N 2.99Å; Y648-V652 HydrophobicContact CD1-CB 4.34Å; Y648-V652 HydrophobicContact CD1-CG2 4.35Å; Y648-V652 HydrophobicContact CD2-CG2 4.18Å; Y648-V652 HydrophobicContact CE1-CB 4.04Å; Y648-V652 HydrophobicContact CE1-CG1 4.12Å; Y648-V652 HydrophobicContact CE1-CG2 4.12Å; Y648-V652 HydrophobicContact CE2-CG2 3.94Å; Y648-V652 HydrophobicContact CG-CG2 4.38Å; Y648-V652 WeakPolarHBondContact O-CB 3.49Å; Y648-V652 PolarHBondContact O-N 2.87Å
649	D	45.3	Very low	37.6	Very low	53 Å²	53	105.8 Å²	105.8	28%	0.283	56%	0.562	S	S	.	*	H	α-helix	trans	-65	-32.8	176.9	-79.1	-38.3	0	0	0	112	Q645 K653	Q645-D649 PolarHBondContact O-N 2.66Å; D649-K653 PolarHBondContact O-N 3.38Å; D649-K653 WeakPolarHBondContact OD1-CD 3.29Å; D649-K653 WeakPolarHBondContact OD1-CE 3.17Å; D649-K653 IonicContact OD1-NZ 3.65Å; D649-K653 PolarHBondContact OD1-NZ 3.1Å
650	R	40.5	Very low	37.6	Very low	193 Å²	193	110 Å²	110	73%	0.728	58%	0.58	S	S	*	*	H	α-helix	trans	-66.8	-41.7	174.2	-107.6	-177.8	-173.2	167.8	4	113.9	A646 A647 Y648	A646-R650 PolarHBondContact O-N 3.22Å; A647-R650 PolarHBondContact O-N 3.2Å; Y648-R650 VanDerWaalsContact C-N 3.3Å; Y648-R650 PolarHBondContact O-N 3.13Å
651	Y	37.8	Very low	37.8	Very low	126 Å²	126	110.2 Å²	110.2	49%	0.494	58%	0.577	S	S	.	*	H	α-helix	trans	-93.3	-23.2	-171	-73.2	-71.5	0	0	0	114.3	F622 A647 Y648	F622-Y651 HydrophobicContact CE1-CE1 4.01Å; A647-Y651 WeakPolarHBondContact O-CD2 3.47Å; A647-Y651 PolarHBondContact O-N 2.98Å; Y648-Y651 PolarHBondContact O-N 2.99Å
652	V	48.4	Very low	37.7	Very low	77 Å²	77	113.8 Å²	113.8	47%	0.467	58%	0.584	S	S	.	*	H	α-helix	trans	-110.8	-29	-172.3	-176.4	0	0	0	0	113.6	Y648	Y648-V652 HydrophobicContact CD1-CB 4.34Å; Y648-V652 HydrophobicContact CD1-CG2 4.35Å; Y648-V652 HydrophobicContact CD2-CG2 4.18Å; Y648-V652 HydrophobicContact CE1-CB 4.04Å; Y648-V652 HydrophobicContact CE1-CG1 4.12Å; Y648-V652 HydrophobicContact CE1-CG2 4.12Å; Y648-V652 HydrophobicContact CE2-CG2 3.94Å; Y648-V652 HydrophobicContact CG-CG2 4.38Å; Y648-V652 WeakPolarHBondContact O-CB 3.49Å; Y648-V652 PolarHBondContact O-N 2.87Å
653	K	40.1	Very low	38.1	Very low	151 Å²	151	117.6 Å²	117.6	66%	0.657	60%	0.599	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96	-23.9	-176.2	-92.1	-175.2	-171.5	149.4	0	115.5	D649	D649-K653 PolarHBondContact O-N 3.38Å; D649-K653 WeakPolarHBondContact OD1-CD 3.29Å; D649-K653 WeakPolarHBondContact OD1-CE 3.17Å; D649-K653 IonicContact OD1-NZ 3.65Å; D649-K653 PolarHBondContact OD1-NZ 3.1Å
654	E	38	Very low	38.1	Very low	121 Å²	121	120.6 Å²	120.6	57%	0.565	60%	0.599	S	S	*	*			trans	-95.5	5.4	-172.8	-72.7	-167	146	0	0	118.9	Y656	E654-Y656 PolarHBondContact O-N 3.05Å
655	P	38.2	Very low	37.9	Very low	66 Å²	66	124.6 Å²	124.6	43%	0.429	62%	0.617	S	S	.	*	T	Hydrogen-bonded Turn	trans	-76.4	6.6	-170.5	26.7	-28.1	0	0	0	116.4
656	Y	36.1	Very low	37.9	Very low	225 Å²	225	123.9 Å²	123.9	88%	0.882	62%	0.624	S	S	*	*	T	Hydrogen-bonded Turn	trans	-141.9	8.1	-171.9	-75	-78.5	0	0	0	118	E654	E654-Y656 PolarHBondContact O-N 3.05Å
657	S	33.4	Very low	37.8	Very low	88 Å²	88	125.5 Å²	125.5	62%	0.615	64%	0.637	S	S	*	*	S	Bend	trans	-118.8	10.1	-165	64.1	0	0	0	0	118.9
658	K	33	Very low	37.7	Very low	171 Å²	171	134 Å²	134	74%	0.743	67%	0.671	S	S	*	*			trans	-136.8	120.1	173.5	-70.5	-177	-178.7	168.4	0	113.1	V660	K658-V660 PolarHBondContact O-N 3.24Å
659	P	33.7	Very low	37.5	Very low	127 Å²	127	138.2 Å²	138.2	83%	0.825	70%	0.699	S	S	*	*			trans	-66	127	165.4	27.8	-30	0	0	0	108.5	S661	P659-S661 PolarHBondContact O-N 3.04Å
660	V	35.1	Very low	37	Very low	123 Å²	123	139.2 Å²	139.2	75%	0.745	72%	0.723	S	S	*	*			trans	-70.4	111.1	176.1	178.7	0	0	0	0	108.1	K658 F662	K658-V660 PolarHBondContact O-N 3.24Å; V660-F662 PolarHBondContact O-N 3.3Å
661	S	31	Very low	36.7	Very low	87 Å²	87	139.9 Å²	139.9	61%	0.608	73%	0.731	S	S	*	*			trans	-74	120	170	66.5	0	0	0	0	109.5	P659 E663	P659-S661 PolarHBondContact O-N 3.04Å; S661-E663 PolarHBondContact O-N 2.97Å; S661-E663 VanDerWaalsContact O-N 3.08Å
662	F	35.2	Very low	36.7	Very low	171 Å²	171	143.1 Å²	143.1	75%	0.75	75%	0.751	S	S	*	*	S	Bend	trans	-72.1	9.2	-177.8	-98.4	-93.5	0	0	0	115.4	V660 K664	V660-F662 PolarHBondContact O-N 3.3Å; F662-K664 PolarHBondContact O-N 3.05Å
663	E	39.3	Very low	35.8	Very low	178 Å²	178	155 Å²	155	83%	0.832	79%	0.787	S	S	*	*			trans	-91.5	11.1	-168.4	-94.6	175.5	153.2	0	0	116.4	S661	S661-E663 PolarHBondContact O-N 2.97Å; S661-E663 VanDerWaalsContact O-N 3.08Å
664	K	37.7	Very low	35.6	Very low	195 Å²	195	155.2 Å²	155.2	85%	0.848	79%	0.793	S	S	*	*			trans	-139	58.8	-177.6	-65.9	-173.6	-178.8	177.8	0	113.9	F662	F662-K664 PolarHBondContact O-N 3.05Å
665	L	35.2	Very low	35.4	Very low	148 Å²	148	156.9 Å²	156.9	78%	0.775	81%	0.805	S	S	*	*			trans	-100.8	126.5	160.6	-98.2	142.6	0	0	0	109.4	A667	L665-A667 PolarHBondContact O-N 3.47Å
666	P	39.4	Very low	35.3	Very low	116 Å²	116	162 Å²	162	75%	0.753	83%	0.826	S	S	*	*			trans	-70.7	120.3	-177	26.4	-31.3	0	0	0	111.5	K668	P666-K668 PolarHBondContact O-N 2.86Å
667	A	39.2	Very low	35.2	Very low	104 Å²	104	158.3 Å²	158.3	86%	0.86	82%	0.823	S	S	*	*			trans	-67.7	88.8	171.3	0	0	0	0	0	111.2	L665	L665-A667 PolarHBondContact O-N 3.47Å
668	K	37.2	Very low	35.3	Very low	193 Å²	193	162.7 Å²	162.7	84%	0.839	84%	0.836	S	S	*	*			trans	-151.3	86.2	164.2	-80.8	-163.8	178.1	-177.4	0	110	P666	P666-K668 PolarHBondContact O-N 2.86Å
669	L	34.3	Very low	35.5	Very low	189 Å²	189	162.1 Å²	162.1	99%	0.99	84%	0.842	S	S	*	*			trans	-173.8	94.5	154.7	-97.6	143.9	0	0	0	106.6
670	G	34.5	Very low	35.6	Very low	75 Å²	75	164.6 Å²	164.6	77%	0.773	84%	0.843	S	S	*	*			trans	170.4	61.6	-173.5	0	0	0	0	0	111.6
671	K	34.7	Very low	35.7	Very low	206 Å²	206	167.8 Å²	167.8	90%	0.896	85%	0.851	S	S	*	*			trans	-179.9	88.1	159.7	-104.6	173.9	-175.5	-178.2	0	108.7
672	E	36.3	Very low	36.1	Very low	195 Å²	195	174.6 Å²	174.6	91%	0.911	87%	0.871	S	S	*	*			trans	-165.8	102.7	145.8	-107.6	176.2	-159.8	0	0	108.8
673	R	29.7	Very low	36.1	Very low	325 Å²	325	174.9 Å²	174.9	100%	1.226	88%	0.882	S	S	*	*			trans	80.3	0	179.3	-63.9	-171.8	-164.9	-167.5	4.8	119.2

Retrieved 673 of 673 residues in 294.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).