A0A077ZKZ9_TRITR Loading...

methylmalonyl-CoA mutase

AlphaFold DB , UniProt , Accession A0A077ZKZ9, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 714 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M66.1Low90Very high239 Ų239103.9 Ų103.9100%1.17753%0.531SS*.  0136.80-68.1173-172.900107
2S76.7Confident90.5Very high118 Ų11899.3 Ų99.383%0.82551%0.509SS*.  trans-62.7137.2173.539.20000110.1
3N88Confident91Very high65 Ų65103.8 Ų103.835%0.34852%0.522SS..  trans-93.1133.8-179.5178.5-3.7000110.3Q5 E6 W7N3-Q5 PolarHBondContact O-N 2.95Å; N3-Q5 WeakPolarHBondContact OD1-CB 3.42Å; N3-Q5 PolarHBondContact OD1-N 2.91Å; N3-E6 HydrophobicContact CB-CB 4.22Å; N3-E6 HydrophobicContact CB-CG 3.89Å; N3-E6 WeakPolarHBondContact O-CB 3.32Å; N3-E6 PolarHBondContact O-N 2.98Å; N3-W7 PolarHBondContact O-N 2.98Å; N3-W7 VanDerWaalsContact O-N 3.07Å
4V92.6Very high91.3Very high72 Ų72104.6 Ų104.644%0.43652%0.523SS..Hα-helixtrans-56.2-34.8175.5175.60000111.8W7 Q8 T40V4-W7 PolarHBondContact O-N 3.05Å; V4-Q8 WeakPolarHBondContact O-CB 3.39Å; V4-Q8 PolarHBondContact O-N 3.23Å; V4-T40 HydrophobicContact CG2-CG2 3.9Å
5Q93.5Very high91.7Very high126 Ų12699 Ų9959%0.58950%0.496SS*.Hα-helixtrans-66.6-39.5176.5-63.4176.4-12.900112.1N3 Q8 Q9N3-Q5 PolarHBondContact O-N 2.95Å; N3-Q5 WeakPolarHBondContact OD1-CB 3.42Å; N3-Q5 PolarHBondContact OD1-N 2.91Å; Q5-Q8 PolarHBondContact O-N 3.33Å; Q5-Q9 VanDerWaalsContact O-CG 3.29Å; Q5-Q9 WeakPolarHBondContact O-CG 3.38Å; Q5-Q9 PolarHBondContact O-N 2.89Å
6E94.6Very high91.8Very high117 Ų11797.4 Ų97.455%0.54750%0.496SS..Hα-helixtrans-65.5-41.9175.6-69.7172.3175.100110.8N3 Q9 L10N3-E6 HydrophobicContact CB-CB 4.22Å; N3-E6 HydrophobicContact CB-CG 3.89Å; N3-E6 WeakPolarHBondContact O-CB 3.32Å; N3-E6 PolarHBondContact O-N 2.98Å; E6-Q9 PolarHBondContact O-N 2.94Å; E6-L10 PolarHBondContact O-N 3.43Å
7W95.7Very high91.8Very high89 Ų89105.3 Ų105.334%0.33752%0.519SS..Hα-helixtrans-60.7-46.3173172.484.9000111.6N3 V4 Q9 L10 A11 V22 P37 L38N3-W7 PolarHBondContact O-N 2.98Å; N3-W7 VanDerWaalsContact O-N 3.07Å; V4-W7 PolarHBondContact O-N 3.05Å; W7-Q9 VanDerWaalsContact C-N 3.31Å; W7-Q9 PolarHBondContact O-N 3.32Å; W7-L10 PolarHBondContact O-N 3Å; W7-A11 HydrophobicContact CZ2-CB 4.19Å; W7-A11 WeakPolarHBondContact O-CB 3.27Å; W7-A11 PolarHBondContact O-N 3.35Å; W7-V22 HydrophobicContact CH2-CG1 3.78Å; W7-V22 HydrophobicContact CH2-CG2 4.23Å; W7-V22 HydrophobicContact CZ3-CG1 3.78Å; W7-V22 HydrophobicContact CZ3-CG2 4.29Å; W7-P37 HydrophobicContact CH2-CG 4.13Å; W7-L38 HydrophobicContact CD2-CD2 3.47Å; W7-L38 VanDerWaalsContact CD2-CD2 3.47Å; W7-L38 HydrophobicContact CE3-CD2 3.74Å; W7-L38 HydrophobicContact CG-CD2 3.91Å; W7-L38 HydrophobicContact CH2-CB 3.63Å; W7-L38 HydrophobicContact CH2-CD2 4.2Å; W7-L38 HydrophobicContact CZ2-CB 3.69Å; W7-L38 HydrophobicContact CZ2-CD2 3.97Å; W7-L38 HydrophobicContact CZ2-CG 4.4Å; W7-L38 HydrophobicContact CZ3-CB 4.09Å; W7-L38 HydrophobicContact CZ3-CD2 4.09Å
8Q95.4Very high91.9Very high70 Ų70109.4 Ų109.433%0.32753%0.528SS..Hα-helixtrans-62.9-38.7-179.7-169.5178.21100111.5V4 Q5 N12 V22V4-Q8 WeakPolarHBondContact O-CB 3.39Å; V4-Q8 PolarHBondContact O-N 3.23Å; Q5-Q8 PolarHBondContact O-N 3.33Å; Q8-N12 VanDerWaalsContact O-CB 3.26Å; Q8-N12 WeakPolarHBondContact O-CB 3.49Å; Q8-N12 PolarHBondContact O-N 2.91Å; Q8-N12 PolarHBondContact O-ND2 2.9Å; Q8-N12 VanDerWaalsContact O-ND2 3.09Å; Q8-V22 HydrophobicContact CG-CB 4.37Å; Q8-V22 HydrophobicContact CG-CG2 4.2Å
9Q95.4Very high92Very high138 Ų138114.3 Ų114.365%0.64555%0.546SS*.Hα-helixtrans-63-46.2173.4-73.6174900111.9Q5 E6 W7 K13Q5-Q9 VanDerWaalsContact O-CG 3.29Å; Q5-Q9 WeakPolarHBondContact O-CG 3.38Å; Q5-Q9 PolarHBondContact O-N 2.89Å; E6-Q9 PolarHBondContact O-N 2.94Å; W7-Q9 VanDerWaalsContact C-N 3.31Å; W7-Q9 PolarHBondContact O-N 3.32Å; Q9-K13 WeakPolarHBondContact O-CB 3.35Å; Q9-K13 PolarHBondContact O-N 2.98Å
10L95.3Very high92.2Very high96 Ų96114 Ų11450%0.50354%0.542SS..Hα-helixtrans-62.7-50.2177.5178.661.4000111.5E6 W7 N12 K13 E14E6-L10 PolarHBondContact O-N 3.43Å; W7-L10 PolarHBondContact O-N 3Å; L10-N12 PolarHBondContact O-N 3.38Å; L10-K13 WeakPolarHBondContact O-CB 3.35Å; L10-K13 PolarHBondContact O-N 2.66Å; L10-K13 VanDerWaalsContact O-N 3.12Å; L10-E14 WeakPolarHBondContact O-CG 3.4Å; L10-E14 PolarHBondContact O-N 3.02Å
11A96.3Very high92.3Very high13 Ų13111.6 Ų111.611%0.10754%0.535CS..Hα-helixtrans-60.3-45.4179.700000111.4W7 K13 E14 L15 V22W7-A11 HydrophobicContact CZ2-CB 4.19Å; W7-A11 WeakPolarHBondContact O-CB 3.27Å; W7-A11 PolarHBondContact O-N 3.35Å; A11-K13 VanDerWaalsContact C-N 3.32Å; A11-K13 PolarHBondContact O-N 3.36Å; A11-E14 PolarHBondContact O-N 2.93Å; A11-L15 WeakPolarHBondContact O-CB 3.36Å; A11-L15 WeakPolarHBondContact O-CD1 3.42Å; A11-L15 WeakPolarHBondContact O-CG 3.48Å; A11-L15 PolarHBondContact O-N 2.84Å; A11-V22 HydrophobicContact CB-CG2 3.52Å
12N96.7Very high93.7Very high49 Ų49100.8 Ų100.826%0.26248%0.482SS..Hα-helixtrans-62.5-38175.1-79.8-38.8000112.3Q8 L10 E14 L15 S16 T21 V22Q8-N12 VanDerWaalsContact O-CB 3.26Å; Q8-N12 WeakPolarHBondContact O-CB 3.49Å; Q8-N12 PolarHBondContact O-N 2.91Å; Q8-N12 PolarHBondContact O-ND2 2.9Å; Q8-N12 VanDerWaalsContact O-ND2 3.09Å; L10-N12 PolarHBondContact O-N 3.38Å; N12-E14 VanDerWaalsContact C-N 3.34Å; N12-E14 PolarHBondContact O-N 2.94Å; N12-L15 PolarHBondContact O-N 3.39Å; N12-S16 PolarHBondContact O-N 3.45Å; N12-T21 VanDerWaalsContact OD1-CA 3.28Å; N12-T21 WeakPolarHBondContact OD1-CA 3.27Å; N12-V22 PolarHBondContact OD1-N 3.49Å
13K96.3Very high94.5Very high157 Ų157100.4 Ų100.468%0.68347%0.471SS*.Hα-helixtrans-62-42.1174.2-176.3-179.7178.2-178.80111.5Q9 L10 A11 S16Q9-K13 WeakPolarHBondContact O-CB 3.35Å; Q9-K13 PolarHBondContact O-N 2.98Å; L10-K13 WeakPolarHBondContact O-CB 3.35Å; L10-K13 PolarHBondContact O-N 2.66Å; L10-K13 VanDerWaalsContact O-N 3.12Å; A11-K13 VanDerWaalsContact C-N 3.32Å; A11-K13 PolarHBondContact O-N 3.36Å; K13-S16 WeakPolarHBondContact O-CB 3.17Å; K13-S16 PolarHBondContact O-OG 3.1Å
14E96.2Very high94.9Very high116 Ų116100.5 Ų100.554%0.54248%0.477SS..Hα-helixtrans-68.4-39.2176.4-68.9177.8-178.700112.7L10 A11 N12 S16L10-E14 WeakPolarHBondContact O-CG 3.4Å; L10-E14 PolarHBondContact O-N 3.02Å; A11-E14 PolarHBondContact O-N 2.93Å; N12-E14 VanDerWaalsContact C-N 3.34Å; N12-E14 PolarHBondContact O-N 2.94Å; E14-S16 VanDerWaalsContact C-N 3.33Å
15L96.5Very high95.1Very high20 Ų20100.3 Ų100.311%0.10547%0.473CS..Hα-helixtrans-74.7-21.1179.8-68168000113.4A11 N12 R17 R18 K19 K20 V22 L25A11-L15 WeakPolarHBondContact O-CB 3.36Å; A11-L15 WeakPolarHBondContact O-CD1 3.42Å; A11-L15 WeakPolarHBondContact O-CG 3.48Å; A11-L15 PolarHBondContact O-N 2.84Å; N12-L15 PolarHBondContact O-N 3.39Å; L15-R17 PolarHBondContact O-N 3.37Å; L15-R17 VanDerWaalsContact O-N 3.16Å; L15-R18 CarbonylContact O-C 3.51Å; L15-R18 WeakPolarHBondContact O-CA 3.38Å; L15-R18 PolarHBondContact O-N 2.69Å; L15-K19 PolarHBondContact O-N 2.8Å; L15-K20 CarbonylContact C-O 3.57Å; L15-K20 HydrophobicContact CB-CB 4.14Å; L15-K20 VanDerWaalsContact CB-O 3.23Å; L15-K20 WeakPolarHBondContact CB-O 3.29Å; L15-K20 HydrophobicContact CD2-CB 4.22Å; L15-K20 PolarHBondContact O-N 3.12Å; L15-V22 HydrophobicContact CD1-CG2 4.12Å; L15-L25 HydrophobicContact CD1-CD1 3.65Å; L15-L25 HydrophobicContact CD1-CG 4.15Å; L15-L25 HydrophobicContact CD2-CD1 4.03Å; L15-L25 HydrophobicContact CD2-CD2 4.35Å; L15-L25 HydrophobicContact CG-CD1 4.46Å
16S93.6Very high95.2Very high73 Ų7396.8 Ų96.851%0.5146%0.46SS..G310 helixtrans-53.5-37.4178.170.70000112.6N12 K13 E14 R18 K19N12-S16 PolarHBondContact O-N 3.45Å; K13-S16 WeakPolarHBondContact O-CB 3.17Å; K13-S16 PolarHBondContact O-OG 3.1Å; E14-S16 VanDerWaalsContact C-N 3.33Å; S16-R18 PolarHBondContact O-N 2.99Å; S16-K19 PolarHBondContact O-N 2.78Å
17R92.4Very high95.2Very high232 Ų23295.6 Ų95.688%0.87546%0.455SS*.G310 helixtrans-63-23.6176.1-67.5-176.5178.2164.6-0.4113.5L15L15-R17 PolarHBondContact O-N 3.37Å; L15-R17 VanDerWaalsContact O-N 3.16Å
18R92.9Very high95.2Very high180 Ų18096.7 Ų96.768%0.67946%0.463SS*.G310 helixtrans-102.66.8178.2-61.9-177.1177.995.3-4.3112.6L15 S16 K20L15-R18 CarbonylContact O-C 3.51Å; L15-R18 WeakPolarHBondContact O-CA 3.38Å; L15-R18 PolarHBondContact O-N 2.69Å; S16-R18 PolarHBondContact O-N 2.99Å; R18-K20 HydrophobicContact CB-CG 4.43Å; R18-K20 PolarHBondContact O-N 3.23Å
19K94.4Very high95.2Very high202 Ų20294 Ų9488%0.87845%0.452SS*.THydrogen-bonded Turntrans5338.1-173.4-56.2179.7179.3179.70112.5L15 S16L15-K19 PolarHBondContact O-N 2.8Å; S16-K19 PolarHBondContact O-N 2.78Å
20K94.7Very high95.2Very high107 Ų10790 Ų9047%0.46544%0.442SS..  trans-118.7161.6177.7-71.1-169.8178.8-168.20110.7L15 R18 S24 L25L15-K20 CarbonylContact C-O 3.57Å; L15-K20 HydrophobicContact CB-CB 4.14Å; L15-K20 VanDerWaalsContact CB-O 3.23Å; L15-K20 WeakPolarHBondContact CB-O 3.29Å; L15-K20 HydrophobicContact CD2-CB 4.22Å; L15-K20 PolarHBondContact O-N 3.12Å; R18-K20 HydrophobicContact CB-CG 4.43Å; R18-K20 PolarHBondContact O-N 3.23Å; K20-S24 WeakPolarHBondContact CB-OG 3.49Å; K20-L25 HydrophobicContact CD-CD2 4.11Å
21T95.6Very high95.2Very high65 Ų6586.8 Ų86.840%0.39943%0.425SS..  trans-123.7164.2169.963.20000110N12 D23 S24 L25N12-T21 VanDerWaalsContact OD1-CA 3.28Å; N12-T21 WeakPolarHBondContact OD1-CA 3.27Å; T21-D23 PolarHBondContact O-N 3.42Å; T21-S24 PolarHBondContact N-OG 3.38Å; T21-S24 PolarHBondContact O-N 3.5Å; T21-S24 VanDerWaalsContact O-N 3.1Å; T21-S24 PolarHBondContact O-OG 3.39Å; T21-S24 PolarHBondContact OG1-N 2.95Å; T21-L25 PolarHBondContact O-N 3.15Å
22V95.3Very high95.2Very high11 Ų1188.5 Ų88.57%0.06744%0.444CS..SBendtrans-53.6-42.8171.9171.50000110.9W7 Q8 A11 N12 L15 S24 L25 P37W7-V22 HydrophobicContact CH2-CG1 3.78Å; W7-V22 HydrophobicContact CH2-CG2 4.23Å; W7-V22 HydrophobicContact CZ3-CG1 3.78Å; W7-V22 HydrophobicContact CZ3-CG2 4.29Å; Q8-V22 HydrophobicContact CG-CB 4.37Å; Q8-V22 HydrophobicContact CG-CG2 4.2Å; A11-V22 HydrophobicContact CB-CG2 3.52Å; N12-V22 PolarHBondContact OD1-N 3.49Å; L15-V22 HydrophobicContact CD1-CG2 4.12Å; V22-S24 VanDerWaalsContact C-N 3.28Å; V22-S24 PolarHBondContact O-N 3.41Å; V22-L25 WeakPolarHBondContact O-CB 3.46Å; V22-L25 PolarHBondContact O-N 2.81Å; V22-P37 HydrophobicContact CG1-CG 3.86Å
23D94.1Very high95.2Very high110 Ų11086.2 Ų86.259%0.58843%0.432SS*.G310 helixtrans-63-35.3179.5-56.9-18.2000111.9T21 L25 V26T21-D23 PolarHBondContact O-N 3.42Å; D23-L25 PolarHBondContact O-N 3.16Å; D23-V26 WeakPolarHBondContact O-CB 3.41Å; D23-V26 WeakPolarHBondContact O-CG2 3.41Å; D23-V26 PolarHBondContact O-N 3.24Å
24S95.3Very high95.3Very high68 Ų6880.6 Ų80.648%0.47641%0.414SS..G310 helixtrans-70.1-10.2175.376.10000114.3K20 T21 V22K20-S24 WeakPolarHBondContact CB-OG 3.49Å; T21-S24 PolarHBondContact N-OG 3.38Å; T21-S24 PolarHBondContact O-N 3.5Å; T21-S24 VanDerWaalsContact O-N 3.1Å; T21-S24 PolarHBondContact O-OG 3.39Å; T21-S24 PolarHBondContact OG1-N 2.95Å; V22-S24 VanDerWaalsContact C-N 3.28Å; V22-S24 PolarHBondContact O-N 3.41Å
25L96Very high95.4Very high67 Ų6776.1 Ų76.135%0.35139%0.394SS..G310 helixtrans-90.3-8.2174.4-57.9-176.2000112.9L15 K20 T21 V22 D23 H27 P37L15-L25 HydrophobicContact CD1-CD1 3.65Å; L15-L25 HydrophobicContact CD1-CG 4.15Å; L15-L25 HydrophobicContact CD2-CD1 4.03Å; L15-L25 HydrophobicContact CD2-CD2 4.35Å; L15-L25 HydrophobicContact CG-CD1 4.46Å; K20-L25 HydrophobicContact CD-CD2 4.11Å; T21-L25 PolarHBondContact O-N 3.15Å; V22-L25 WeakPolarHBondContact O-CB 3.46Å; V22-L25 PolarHBondContact O-N 2.81Å; D23-L25 PolarHBondContact O-N 3.16Å; L25-H27 PolarHBondContact O-N 2.92Å; L25-P37 HydrophobicContact CB-CB 4.11Å; L25-P37 HydrophobicContact CB-CG 4.14Å; L25-P37 HydrophobicContact CD1-CB 4.33Å
26V96.9Very high95.4Very high52 Ų5278.6 Ų78.632%0.31540%0.404SS..PPolyproline II helixtrans-62.2120174.8176.80000108.6D23 A34 I35D23-V26 WeakPolarHBondContact O-CB 3.41Å; D23-V26 WeakPolarHBondContact O-CG2 3.41Å; D23-V26 PolarHBondContact O-N 3.24Å; V26-A34 HydrophobicContact CG1-CB 3.94Å; V26-I35 WeakPolarHBondContact CA-O 3.28Å
27H94.9Very high95.6Very high93 Ų9377.9 Ų77.943%0.43140%0.397SS..EExtended strand (participates in β ladder)trans-96.7122.6-178.2-173.164.5000110L25 I35 R451L25-H27 PolarHBondContact O-N 2.92Å; H27-I35 HydrophobicContact CB-CB 4.44Å; H27-I35 PolarHBondContact N-O 3.01Å; H27-I35 PolarHBondContact O-N 2.76Å; H27-R451 PolarHBondContact CE1-NH1 2.98Å; H27-R451 PolarHBondContact NE2-NH1 3.23Å; H27-R451 VanDerWaalsContact NE2-NH1 3.16Å
28Q94.8Very high95.8Very high112 Ų11270 Ų7052%0.52337%0.372SS..EExtended strand (participates in β ladder)trans-84.9119.1171.4-61.2-60.6-34.100109
29T96.3Very high96Very high14 Ų1462.6 Ų62.69%0.08634%0.344CS..PPolyproline II helixtrans-84.2168.7179.275.50000111.7E31 G32 I33 I35 M285T29-E31 WeakPolarHBondContact CB-OE2 3.48Å; T29-E31 PolarHBondContact O-N 2.89Å; T29-E31 PolarHBondContact OG1-N 3.21Å; T29-E31 PolarHBondContact OG1-OE2 3.02Å; T29-G32 PolarHBondContact O-N 3.3Å; T29-I33 PolarHBondContact N-O 2.94Å; T29-I33 PolarHBondContact OG1-N 3.37Å; T29-I33 PolarHBondContact OG1-O 2.95Å; T29-I35 HydrophobicContact CG2-CD1 4.08Å; T29-I35 HydrophobicContact CG2-CG1 3.43Å; T29-I35 VanDerWaalsContact CG2-CG1 3.43Å; T29-M285 HydrophobicContact CG2-CE 3.83Å
30A93.8Very high96.1Very high54 Ų5454.6 Ų54.645%0.44631%0.313SS..THydrogen-bonded Turntrans-65.2-22175.600000112.7G32 N240A30-G32 VanDerWaalsContact C-N 3.26Å; A30-G32 PolarHBondContact O-N 3.01Å; A30-N240 PolarHBondContact O-ND2 2.72Å
31E96.8Very high96.2Very high27 Ų2756.1 Ų56.113%0.12632%0.322CS..THydrogen-bonded Turntrans-73.1-15.8173.5-6471.1-159.400112.6T29 I33 N240 C241 V242 M285 Q408T29-E31 WeakPolarHBondContact CB-OE2 3.48Å; T29-E31 PolarHBondContact O-N 2.89Å; T29-E31 PolarHBondContact OG1-N 3.21Å; T29-E31 PolarHBondContact OG1-OE2 3.02Å; E31-I33 HydrophobicContact CB-CD1 4.06Å; E31-I33 HydrophobicContact CB-CG1 4.08Å; E31-N240 HydrophobicContact CG-CB 4.04Å; E31-C241 HydrophobicContact CG-CB 4.19Å; E31-C241 PolarHBondContact OE1-N 3.2Å; E31-V242 HydrophobicContact CB-CB 4.36Å; E31-V242 HydrophobicContact CB-CG2 3.78Å; E31-V242 HydrophobicContact CG-CB 4.26Å; E31-V242 HydrophobicContact CG-CG2 3.82Å; E31-M285 HydrophobicContact CG-CE 4.22Å; E31-M285 HydrophobicContact CG-CG 4.44Å; E31-M285 HydrophobicContact CG-SD 4Å; E31-M285 WeakPolarHBondContact OE2-CE 3.34Å; E31-Q408 PolarHBondContact O-OE1 3.48Å
32G95.6Very high96.1Very high50 Ų5055.9 Ų55.952%0.51533%0.326SS..SBendtrans80.327.5-170.400000112.6T29 A30 Q408T29-G32 PolarHBondContact O-N 3.3Å; A30-G32 VanDerWaalsContact C-N 3.26Å; A30-G32 PolarHBondContact O-N 3.01Å; G32-Q408 PolarHBondContact O-NE2 3.39Å; G32-Q408 VanDerWaalsContact O-NE2 3.13Å
33I97.7Very high96.2Very high1 Ų157.1 Ų57.11%0.00533%0.332CS..  trans-100.6130.9174.9-64.5174.3000109T29 E31 I35 V242 M285 L401 Q404 I405 Q408T29-I33 PolarHBondContact N-O 2.94Å; T29-I33 PolarHBondContact OG1-N 3.37Å; T29-I33 PolarHBondContact OG1-O 2.95Å; E31-I33 HydrophobicContact CB-CD1 4.06Å; E31-I33 HydrophobicContact CB-CG1 4.08Å; I33-I35 HydrophobicContact CG2-CD1 3.61Å; I33-I35 HydrophobicContact CG2-CG1 4.46Å; I33-V242 HydrophobicContact CD1-CG2 4.3Å; I33-M285 HydrophobicContact CD1-CE 4.22Å; I33-M285 HydrophobicContact CD1-SD 4.14Å; I33-L401 HydrophobicContact CD1-CD1 4.02Å; I33-L401 HydrophobicContact CG2-CD1 3.91Å; I33-Q404 HydrophobicContact CD1-CB 4.11Å; I33-Q404 HydrophobicContact CG1-CB 4.39Å; I33-Q404 HydrophobicContact CG2-CB 4.45Å; I33-I405 HydrophobicContact CD1-CG1 3.85Å; I33-Q408 VanDerWaalsContact CG1-NE2 3.28Å
34A97.7Very high96.3Very high38 Ų3854 Ų5431%0.31432%0.315SS..EExtended strand (participates in β ladder)trans-89105.2176.100000110.3V26V26-A34 HydrophobicContact CG1-CB 3.94Å
35I97.9Very high96.3Very high22 Ų2255.8 Ų55.811%0.11332%0.319CS..EExtended strand (participates in β ladder)trans-86.5118.9-178.8-52-66.7000109.7V26 H27 T29 I33 Y39 Y397 L401V26-I35 WeakPolarHBondContact CA-O 3.28Å; H27-I35 HydrophobicContact CB-CB 4.44Å; H27-I35 PolarHBondContact N-O 3.01Å; H27-I35 PolarHBondContact O-N 2.76Å; T29-I35 HydrophobicContact CG2-CD1 4.08Å; T29-I35 HydrophobicContact CG2-CG1 3.43Å; T29-I35 VanDerWaalsContact CG2-CG1 3.43Å; I33-I35 HydrophobicContact CG2-CD1 3.61Å; I33-I35 HydrophobicContact CG2-CG1 4.46Å; I35-Y39 HydrophobicContact CG2-CE2 4.31Å; I35-Y397 HydrophobicContact CD1-CE2 3.91Å; I35-Y397 HydrophobicContact CG2-CE2 3.81Å; I35-L401 HydrophobicContact CD1-CD1 3.72Å
36K97.6Very high96.3Very high73 Ų7360.2 Ų60.232%0.31734%0.343SS..  trans-77.2147.7177.4-58.7-173.8-58169.80110.7L38 Y39 D43K36-L38 WeakPolarHBondContact CB-O 3.41Å; K36-L38 WeakPolarHBondContact CE-O 3.46Å; K36-L38 PolarHBondContact O-N 3.03Å; K36-Y39 HydrophobicContact CB-CD2 4.3Å; K36-Y39 HydrophobicContact CB-CE2 3.8Å; K36-Y39 PolarHBondContact N-OH 3.43Å; K36-Y39 VanDerWaalsContact N-OH 3.16Å; K36-Y39 VanDerWaalsContact O-CE2 3.32Å; K36-Y39 WeakPolarHBondContact O-CE2 3.32Å; K36-D43 IonicContact NZ-OD1 3.88Å; K36-D43 PolarHBondContact NZ-OD1 3.42Å; K36-D43 IonicContact NZ-OD2 3.73Å; K36-D43 PolarHBondContact NZ-OD2 3Å
37P96.6Very high96.3Very high57 Ų5759 Ų5937%0.3734%0.335SS..SBendtrans-67.9-15.6172.827.9-35.9000113.7W7 V22 L25W7-P37 HydrophobicContact CH2-CG 4.13Å; V22-P37 HydrophobicContact CG1-CG 3.86Å; L25-P37 HydrophobicContact CB-CB 4.11Å; L25-P37 HydrophobicContact CB-CG 4.14Å; L25-P37 HydrophobicContact CD1-CB 4.33Å
38L96.8Very high96.4Very high67 Ų6758.6 Ų58.635%0.35133%0.333SS..  trans-146136.3175.7-178.867.2000110.6W7 K36 T40W7-L38 HydrophobicContact CD2-CD2 3.47Å; W7-L38 VanDerWaalsContact CD2-CD2 3.47Å; W7-L38 HydrophobicContact CE3-CD2 3.74Å; W7-L38 HydrophobicContact CG-CD2 3.91Å; W7-L38 HydrophobicContact CH2-CB 3.63Å; W7-L38 HydrophobicContact CH2-CD2 4.2Å; W7-L38 HydrophobicContact CZ2-CB 3.69Å; W7-L38 HydrophobicContact CZ2-CD2 3.97Å; W7-L38 HydrophobicContact CZ2-CG 4.4Å; W7-L38 HydrophobicContact CZ3-CB 4.09Å; W7-L38 HydrophobicContact CZ3-CD2 4.09Å; K36-L38 WeakPolarHBondContact CB-O 3.41Å; K36-L38 WeakPolarHBondContact CE-O 3.46Å; K36-L38 PolarHBondContact O-N 3.03Å; L38-T40 HydrophobicContact CD2-CG2 4.24Å; L38-T40 HydrophobicContact CG-CG2 4.25Å
39Y97.1Very high96.4Very high24 Ų2453.2 Ų53.29%0.09431%0.308CS..  trans-116.2148.7168.9-69.4-101.7000109.5I35 K36 D43 Y396 Y397I35-Y39 HydrophobicContact CG2-CE2 4.31Å; K36-Y39 HydrophobicContact CB-CD2 4.3Å; K36-Y39 HydrophobicContact CB-CE2 3.8Å; K36-Y39 PolarHBondContact N-OH 3.43Å; K36-Y39 VanDerWaalsContact N-OH 3.16Å; K36-Y39 VanDerWaalsContact O-CE2 3.32Å; K36-Y39 WeakPolarHBondContact O-CE2 3.32Å; Y39-D43 VanDerWaalsContact CA-OD2 3.24Å; Y39-D43 WeakPolarHBondContact CA-OD2 3.35Å; Y39-D43 HydrophobicContact CD1-CB 4.07Å; Y39-Y396 WeakPolarHBondContact O-CD2 3.38Å; Y39-Y397 AromaticContact CD2-CD2 3.72Å; Y39-Y397 HydrophobicContact CD2-CD2 3.72Å; Y39-Y397 HydrophobicContact CD2-CG 4.05Å; Y39-Y397 HydrophobicContact CE1-CD2 4.32Å; Y39-Y397 AromaticContact CE2-CD2 3.34Å; Y39-Y397 HydrophobicContact CE2-CD2 3.34Å; Y39-Y397 AromaticContact CE2-CE2 3.91Å; Y39-Y397 HydrophobicContact CE2-CE2 3.91Å; Y39-Y397 HydrophobicContact CE2-CG 4.11Å; Y39-Y397 HydrophobicContact CG-CD2 4.36Å; Y39-Y397 AromaticContact CZ-CD2 3.69Å
40T96.6Very high96.4Very high35 Ų3555 Ų5522%0.21532%0.32CS..  trans-134.5174.9-17565.20000111.2V4 L38 A42 D43 Y396V4-T40 HydrophobicContact CG2-CG2 3.9Å; L38-T40 HydrophobicContact CD2-CG2 4.24Å; L38-T40 HydrophobicContact CG-CG2 4.25Å; T40-A42 PolarHBondContact O-N 3.42Å; T40-D43 PolarHBondContact N-OD2 3.17Å; T40-D43 VanDerWaalsContact O-CB 3.3Å; T40-D43 WeakPolarHBondContact O-CB 3.45Å; T40-D43 PolarHBondContact O-N 3.42Å; T40-D43 PolarHBondContact OG1-OD2 2.97Å; T40-Y396 VanDerWaalsContact C-CG 3.45Å; T40-Y396 WeakPolarHBondContact O-CB 3.46Å
41E95.6Very high96.3Very high139 Ų13956.6 Ų56.665%0.6534%0.34SS*.G310 helixtrans-53.7-37.4176.6-176.1176.1-162.800112.9D43 L44 Y396E41-D43 PolarHBondContact O-N 3.44Å; E41-D43 VanDerWaalsContact O-N 3.1Å; E41-L44 WeakPolarHBondContact O-CB 3.45Å; E41-L44 PolarHBondContact O-N 3.1Å; E41-Y396 HydrophobicContact CB-CE1 4.16Å
42A95.3Very high96.3Very high60 Ų6056.4 Ų56.450%0.49634%0.342SS..G310 helixtrans-62.2-18.6177.300000113.6T40 L44 D45T40-A42 PolarHBondContact O-N 3.42Å; A42-L44 PolarHBondContact O-N 3.16Å; A42-D45 WeakPolarHBondContact O-CB 3.45Å; A42-D45 PolarHBondContact O-N 3.44Å
43D96.8Very high96.4Very high36 Ų3659 Ų5919%0.19334%0.343CS..G310 helixtrans-78.3-9.6175.3-63.7-59.4000113.1K36 Y39 T40 E41 D45 L47 S400K36-D43 IonicContact NZ-OD1 3.88Å; K36-D43 PolarHBondContact NZ-OD1 3.42Å; K36-D43 IonicContact NZ-OD2 3.73Å; K36-D43 PolarHBondContact NZ-OD2 3Å; Y39-D43 VanDerWaalsContact CA-OD2 3.24Å; Y39-D43 WeakPolarHBondContact CA-OD2 3.35Å; Y39-D43 HydrophobicContact CD1-CB 4.07Å; T40-D43 PolarHBondContact N-OD2 3.17Å; T40-D43 VanDerWaalsContact O-CB 3.3Å; T40-D43 WeakPolarHBondContact O-CB 3.45Å; T40-D43 PolarHBondContact O-N 3.42Å; T40-D43 PolarHBondContact OG1-OD2 2.97Å; E41-D43 PolarHBondContact O-N 3.44Å; E41-D43 VanDerWaalsContact O-N 3.1Å; D43-D45 VanDerWaalsContact C-N 3.34Å; D43-L47 WeakPolarHBondContact O-CD1 3.3Å; D43-S400 PolarHBondContact O-OG 3Å
44L96.8Very high96.4Very high44 Ų4459.9 Ų59.923%0.2335%0.349CS..G310 helixtrans-84.2-10.4171.2-60.4-178.8000112.9E41 A42 N46 L47 T50 Y396 E399E41-L44 WeakPolarHBondContact O-CB 3.45Å; E41-L44 PolarHBondContact O-N 3.1Å; A42-L44 PolarHBondContact O-N 3.16Å; L44-N46 PolarHBondContact O-N 2.92Å; L44-L47 HydrophobicContact CD2-CD1 4.11Å; L44-L47 PolarHBondContact O-N 3.09Å; L44-T50 HydrophobicContact CD2-CG2 4.42Å; L44-Y396 HydrophobicContact CD1-CD1 3.66Å; L44-Y396 HydrophobicContact CD1-CE1 3.89Å; L44-Y396 HydrophobicContact CD2-CD1 4.32Å; L44-Y396 HydrophobicContact CG-CD1 3.83Å; L44-Y396 HydrophobicContact CG-CE1 4.49Å; L44-E399 HydrophobicContact CD2-CB 3.61Å; L44-E399 HydrophobicContact CD2-CG 3.9Å
45D95.6Very high96.4Very high106 Ų10659 Ų5957%0.56734%0.343SS*.THydrogen-bonded Turntrans-65.3125.8-176.3-70.2-19.2000111A42 D43 L47A42-D45 WeakPolarHBondContact O-CB 3.45Å; A42-D45 PolarHBondContact O-N 3.44Å; D43-D45 VanDerWaalsContact C-N 3.34Å; D45-L47 VanDerWaalsContact C-N 3.3Å; D45-L47 PolarHBondContact O-N 3.29Å
46N94.5Very high96.3Very high160 Ų16062.6 Ų62.686%0.85636%0.362SS*.THydrogen-bonded Turntrans62.225.8176.7-45.2-70.1000115.5L44L44-N46 PolarHBondContact O-N 2.92Å
47L97.5Very high96.3Very high26 Ų2662.4 Ų62.414%0.13637%0.368CS..  trans-79.6135.1170.3-57.3-171.5000111.5D43 L44 D45 V49 T50 E399 D403D43-L47 WeakPolarHBondContact O-CD1 3.3Å; L44-L47 HydrophobicContact CD2-CD1 4.11Å; L44-L47 PolarHBondContact O-N 3.09Å; D45-L47 VanDerWaalsContact C-N 3.3Å; D45-L47 PolarHBondContact O-N 3.29Å; L47-V49 VanDerWaalsContact C-N 3.3Å; L47-V49 PolarHBondContact O-N 3.41Å; L47-T50 HydrophobicContact CB-CG2 3.82Å; L47-T50 HydrophobicContact CD1-CG2 4.08Å; L47-T50 HydrophobicContact CG-CG2 4.5Å; L47-T50 PolarHBondContact O-OG1 3.24Å; L47-E399 HydrophobicContact CD1-CB 3.86Å; L47-D403 HydrophobicContact CB-CB 4.33Å; L47-D403 HydrophobicContact CD1-CB 4.45Å; L47-D403 HydrophobicContact CD2-CB 3.89Å; L47-D403 HydrophobicContact CG-CB 4.45Å
48E96Very high96.3Very high85 Ų8561.1 Ų61.140%0.39736%0.36SS..THydrogen-bonded Turntrans-74.8-20.6-177.3-67.4175.4-159.700112.9Y295 D403 R410E48-Y295 HydrophobicContact CB-CE2 4.42Å; E48-Y295 WeakPolarHBondContact O-CE2 3.44Å; E48-Y295 PolarHBondContact OE2-OH 2.92Å; E48-D403 PolarHBondContact N-OD1 2.98Å; E48-R410 IonicContact OE1-NH1 2.78Å; E48-R410 PolarHBondContact OE1-NH1 3.18Å; E48-R410 IonicContact OE2-CZ 3.02Å; E48-R410 IonicContact OE2-NH1 3.46Å; E48-R410 PolarHBondContact OE2-NH1 3.4Å; E48-R410 IonicContact OE2-NH2 3.61Å; E48-R410 PolarHBondContact OE2-NH2 2.96Å
49V96.7Very high96.4Very high0 Ų058.3 Ų58.30%035%0.345CS..THydrogen-bonded Turntrans-93.3-6.6-169.8-57.90000114.2L47 V60 Y295 T402 D403 V406L47-V49 VanDerWaalsContact C-N 3.3Å; L47-V49 PolarHBondContact O-N 3.41Å; V49-V60 HydrophobicContact CB-CG1 4.38Å; V49-V60 HydrophobicContact CB-CG2 4.41Å; V49-Y295 HydrophobicContact CG1-CD2 4.05Å; V49-Y295 HydrophobicContact CG1-CE2 4.37Å; V49-Y295 HydrophobicContact CG1-CG 4.33Å; V49-T402 HydrophobicContact CB-CG2 4.3Å; V49-T402 HydrophobicContact CG1-CG2 4.13Å; V49-T402 HydrophobicContact CG2-CG2 4.27Å; V49-D403 HydrophobicContact CG1-CB 4.44Å; V49-D403 HydrophobicContact CG2-CB 3.98Å; V49-V406 HydrophobicContact CG1-CG2 3.92Å
50T94.5Very high96.5Very high52 Ų5257.1 Ų57.132%0.31934%0.34SS..  trans-86.2166.3-176.263.80000112.4L44 L47 T52 E399L44-T50 HydrophobicContact CD2-CG2 4.42Å; L47-T50 HydrophobicContact CB-CG2 3.82Å; L47-T50 HydrophobicContact CD1-CG2 4.08Å; L47-T50 HydrophobicContact CG-CG2 4.5Å; L47-T50 PolarHBondContact O-OG1 3.24Å; T50-T52 VanDerWaalsContact C-N 3.26Å; T50-T52 PolarHBondContact O-N 3.14Å; T50-E399 HydrophobicContact CG2-CB 4.09Å; T50-E399 HydrophobicContact CG2-CG 4.25Å
51G92.3Very high96.6Very high86 Ų8658.3 Ų58.389%0.88734%0.341SS*.SBendtrans72.610.2176.400000115.8
52T96.2Very high96.7Very high24 Ų2451.7 Ų51.715%0.14731%0.31CS..  trans-92.1161.4-178.264.80000112.8T50 P58 V60 R61T50-T52 VanDerWaalsContact C-N 3.26Å; T50-T52 PolarHBondContact O-N 3.14Å; T52-P58 HydrophobicContact CG2-CG 3.89Å; T52-V60 HydrophobicContact CG2-CG2 4.21Å; T52-R61 WeakPolarHBondContact O-CD 3.37Å
53L97.8Very high96.8Very high104 Ų10449.2 Ų49.255%0.54529%0.289SS..  trans-120.5147.1177.4-70.5174.5000110.9L56L53-L56 HydrophobicContact CB-CD1 4.13Å; L53-L56 HydrophobicContact CD1-CD1 4.25Å; L53-L56 PolarHBondContact O-N 3.04Å
54P97.8Very high96.8Very high19 Ų1954 Ų5412%0.12330%0.304CS..THydrogen-bonded Turntrans-63.4144.7176.529.5-36.9000111L56 R61 A65 V389P54-L56 PolarHBondContact O-N 2.9Å; P54-R61 HydrophobicContact CB-CB 4.04Å; P54-A65 WeakPolarHBondContact CG-O 3.35Å; P54-A65 WeakPolarHBondContact O-CA 3.38Å; P54-V389 HydrophobicContact CB-CG1 3.59Å; P54-V389 HydrophobicContact CG-CG1 3.67Å
55G97.7Very high96.9Very high20 Ų2055.2 Ų55.221%0.20632%0.32CS..THydrogen-bonded Turntrans74.12.9-179.700000115.6Y59 G62G55-Y59 VanDerWaalsContact C-CE1 3.41Å; G55-Y59 WeakPolarHBondContact O-CE1 3.32Å; G55-G62 PolarHBondContact N-O 3.22Å
56L97.5Very high97Very high97 Ų9753.6 Ų53.651%0.50831%0.314SS..SBendtrans-120.1143.1173.1-61.1179.4000109.9L53 P54 Y59L53-L56 HydrophobicContact CB-CD1 4.13Å; L53-L56 HydrophobicContact CD1-CD1 4.25Å; L53-L56 PolarHBondContact O-N 3.04Å; P54-L56 PolarHBondContact O-N 2.9Å; L56-Y59 VanDerWaalsContact O-CA 3.3Å; L56-Y59 WeakPolarHBondContact O-CA 3.36Å; L56-Y59 WeakPolarHBondContact O-CD1 3.1Å; L56-Y59 PolarHBondContact O-N 3.28Å
57P96.5Very high97.2Very high69 Ų6946.7 Ų46.745%0.44828%0.277SS..THydrogen-bonded Turntrans-52.8139.3171.8-22.130.9000111.1Y59P57-Y59 HydrophobicContact CB-CD2 4.31Å; P57-Y59 HydrophobicContact CB-CE2 3.89Å; P57-Y59 WeakPolarHBondContact CD-OH 3.33Å; P57-Y59 HydrophobicContact CG-CD2 4.43Å; P57-Y59 HydrophobicContact CG-CE2 3.57Å; P57-Y59 WeakPolarHBondContact CG-OH 3.39Å
58P97.4Very high97.2Very high31 Ų3146.5 Ų46.520%0.20128%0.275CS..THydrogen-bonded Turncis-90.825.77.937.5-37000114.3T52 V60 R294 Y295T52-P58 HydrophobicContact CG2-CG 3.89Å; P58-V60 HydrophobicContact CG-CG2 3.96Å; P58-V60 PolarHBondContact O-N 3.07Å; P58-R294 CarbonylContact O-C 3.15Å; P58-Y295 HydrophobicContact CB-CD2 3.82Å; P58-Y295 HydrophobicContact CB-CE2 4.2Å; P58-Y295 HydrophobicContact CB-CG 4.4Å; P58-Y295 HydrophobicContact CG-CD2 3.55Å; P58-Y295 HydrophobicContact CG-CE2 3.78Å; P58-Y295 WeakPolarHBondContact O-CA 3.41Å
59Y98.4Very high97.3Very high7 Ų745.9 Ų45.93%0.02728%0.277CS..  trans59.217.5171.4-56-75.8000116.5G55 L56 P57 R61 G62 R294 P309 L312 A313G55-Y59 VanDerWaalsContact C-CE1 3.41Å; G55-Y59 WeakPolarHBondContact O-CE1 3.32Å; L56-Y59 VanDerWaalsContact O-CA 3.3Å; L56-Y59 WeakPolarHBondContact O-CA 3.36Å; L56-Y59 WeakPolarHBondContact O-CD1 3.1Å; L56-Y59 PolarHBondContact O-N 3.28Å; P57-Y59 HydrophobicContact CB-CD2 4.31Å; P57-Y59 HydrophobicContact CB-CE2 3.89Å; P57-Y59 WeakPolarHBondContact CD-OH 3.33Å; P57-Y59 HydrophobicContact CG-CD2 4.43Å; P57-Y59 HydrophobicContact CG-CE2 3.57Å; P57-Y59 WeakPolarHBondContact CG-OH 3.39Å; Y59-R61 PolarHBondContact O-N 3.17Å; Y59-R61 VanDerWaalsContact O-N 3.12Å; Y59-G62 PolarHBondContact O-N 3.47Å; Y59-R294 WeakPolarHBondContact O-CD 3.35Å; Y59-R294 PolarHBondContact O-NE 3.12Å; Y59-P309 PolarHBondContact OH-O 3.01Å; Y59-L312 HydrophobicContact CE2-CB 3.72Å; Y59-A313 HydrophobicContact CD2-CB 4.39Å; Y59-A313 HydrophobicContact CE1-CB 4.26Å; Y59-A313 HydrophobicContact CE2-CB 4.16Å
60V98.5Very high97.4Very high0 Ų049.4 Ų49.40%031%0.306CS..THydrogen-bonded Turntrans-50-44.2-179.4-179.80000111.2V49 T52 P58 G62 R291 R294 Y295V49-V60 HydrophobicContact CB-CG1 4.38Å; V49-V60 HydrophobicContact CB-CG2 4.41Å; T52-V60 HydrophobicContact CG2-CG2 4.21Å; P58-V60 HydrophobicContact CG-CG2 3.96Å; P58-V60 PolarHBondContact O-N 3.07Å; V60-G62 VanDerWaalsContact C-N 3.28Å; V60-G62 PolarHBondContact O-N 3.2Å; V60-R291 HydrophobicContact CG1-CB 4.06Å; V60-R294 PolarHBondContact O-NE 2.82Å; V60-R294 VanDerWaalsContact O-NE 3.16Å; V60-R294 PolarHBondContact O-NH2 3.48Å; V60-Y295 HydrophobicContact CG2-CD2 3.63Å; V60-Y295 HydrophobicContact CG2-CG 4.27Å
61R98.4Very high97.4Very high60 Ų6053.8 Ų53.823%0.22632%0.323CS..THydrogen-bonded Turntrans-83.86.1-177.9-52.4-162.262.7-162.1-5.8115.2T52 P54 Y59 V389 D390T52-R61 WeakPolarHBondContact O-CD 3.37Å; P54-R61 HydrophobicContact CB-CB 4.04Å; Y59-R61 PolarHBondContact O-N 3.17Å; Y59-R61 VanDerWaalsContact O-N 3.12Å; R61-V389 PolarHBondContact NH2-O 3.21Å; R61-D390 WeakPolarHBondContact CA-OD2 3.41Å; R61-D390 HydrophobicContact CB-CB 3.98Å; R61-D390 WeakPolarHBondContact CB-OD2 3.44Å; R61-D390 WeakPolarHBondContact CG-OD2 3.29Å; R61-D390 IonicContact CZ-OD2 3.77Å; R61-D390 IonicContact NE-OD2 3.52Å; R61-D390 PolarHBondContact NE-OD2 3.16Å; R61-D390 PolarHBondContact NH2-O 3.03Å
62G98.2Very high97.7Very high0 Ų051.5 Ų51.50%029%0.292CS..  trans123.5151.7175.900000113.5G55 Y59 V60 R64G55-G62 PolarHBondContact N-O 3.22Å; Y59-G62 PolarHBondContact O-N 3.47Å; V60-G62 VanDerWaalsContact C-N 3.28Å; V60-G62 PolarHBondContact O-N 3.2Å; G62-R64 PolarHBondContact O-N 3.13Å
63P97.7Very high97.8Very high7 Ų750.5 Ų50.55%0.04529%0.286CS..SBendtrans-75.1-6.7-175.129.9-36.1000114.4M67 A313 Q350P63-M67 HydrophobicContact CG-SD 4.45Å; P63-A313 HydrophobicContact CB-CB 4.12Å; P63-Q350 HydrophobicContact CG-CG 4.44Å; P63-Q350 VanDerWaalsContact CG-NE2 3.34Å
64R97.4Very high97.6Very high138 Ų13847.6 Ų47.652%0.52127%0.272SS..SBendtrans-128143.4-179.6-59.9-62.5-171.9-169.70.6110.2G62 T66 M67G62-R64 PolarHBondContact O-N 3.13Å; R64-T66 VanDerWaalsContact C-N 3.33Å; R64-T66 PolarHBondContact O-N 3.13Å; R64-M67 HydrophobicContact CB-SD 3.98Å; R64-M67 VanDerWaalsContact O-CG 3.31Å; R64-M67 WeakPolarHBondContact O-CG 3.32Å; R64-M67 PolarHBondContact O-N 2.94Å
65A97.8Very high97.5Very high68 Ų6846.8 Ų46.856%0.56227%0.267SS*.SBendtrans-61.9-38.2-177.600000113.4P54P54-A65 WeakPolarHBondContact CG-O 3.35Å; P54-A65 WeakPolarHBondContact O-CA 3.38Å
66T98.2Very high97.3Very high72 Ų7246.7 Ų46.744%0.44226%0.261SS..SBendtrans-95.3-15.9-177.556.40000113.7R64 Y68 T69 A70 V389R64-T66 VanDerWaalsContact C-N 3.33Å; R64-T66 PolarHBondContact O-N 3.13Å; T66-Y68 PolarHBondContact O-N 3.29Å; T66-T69 PolarHBondContact O-N 3.1Å; T66-T69 VanDerWaalsContact O-N 3.07Å; T66-T69 PolarHBondContact O-OG1 3.03Å; T66-A70 HydrophobicContact CG2-CB 4.37Å; T66-A70 WeakPolarHBondContact OG1-CB 3.36Å; T66-V389 VanDerWaalsContact O-CG2 3.29Å; T66-V389 WeakPolarHBondContact O-CG2 3.44Å
67M98.5Very high97.1Very high16 Ų1642.7 Ų42.78%0.07924%0.239CC..G310 helixtrans38.4-127.2-170.9-66.4-59.7-75.700111.7P63 R64 T69 G348 V389P63-M67 HydrophobicContact CG-SD 4.45Å; R64-M67 HydrophobicContact CB-SD 3.98Å; R64-M67 VanDerWaalsContact O-CG 3.31Å; R64-M67 WeakPolarHBondContact O-CG 3.32Å; R64-M67 PolarHBondContact O-N 2.94Å; M67-T69 VanDerWaalsContact C-N 3.3Å; M67-T69 PolarHBondContact O-N 2.82Å; M67-G348 WeakPolarHBondContact CE-O 3.38Å; M67-V389 HydrophobicContact CB-CG1 3.95Å; M67-V389 HydrophobicContact CB-CG2 4.21Å; M67-V389 HydrophobicContact CG-CG1 3.63Å
68Y98.5Very high96.5Very high21 Ų2142 Ų428%0.08223%0.228CC..G310 helixtrans-75.2-13.7-173.9-51.6-32.5000115.1T66 A70 Q71 W73 T345 G348 T349 L385 C386T66-Y68 PolarHBondContact O-N 3.29Å; Y68-A70 PolarHBondContact O-N 2.99Å; Y68-Q71 WeakPolarHBondContact CA-O 3.41Å; Y68-Q71 PolarHBondContact O-N 3.34Å; Y68-W73 HydrophobicContact CD1-CE3 4.36Å; Y68-W73 HydrophobicContact CD2-CE3 4.28Å; Y68-W73 HydrophobicContact CD2-CZ3 4.5Å; Y68-W73 HydrophobicContact CE1-CB 3.97Å; Y68-W73 HydrophobicContact CE1-CE3 4.15Å; Y68-W73 HydrophobicContact CE2-CE3 4.04Å; Y68-W73 HydrophobicContact CE2-CZ3 4.45Å; Y68-W73 HydrophobicContact CG-CE3 4.42Å; Y68-W73 AromaticContact CZ-CE3 3.97Å; Y68-T345 VanDerWaalsContact CE2-O 3.26Å; Y68-T345 WeakPolarHBondContact CE2-O 3.41Å; Y68-T345 PolarHBondContact OH-O 2.59Å; Y68-G348 VanDerWaalsContact OH-CA 3.28Å; Y68-G348 WeakPolarHBondContact OH-CA 3.41Å; Y68-T349 VanDerWaalsContact CE1-O 3.27Å; Y68-T349 WeakPolarHBondContact CE1-O 3.33Å; Y68-T349 PolarHBondContact OH-N 3.29Å; Y68-T349 PolarHBondContact OH-O 2.87Å; Y68-L385 HydrophobicContact CD2-CD2 3.94Å; Y68-L385 HydrophobicContact CE2-CD2 4.15Å; Y68-C386 CarbonylContact C-O 3.45Å
69T98Very high95.9Very high72 Ų7241 Ų4144%0.44222%0.223SC..G310 helixtrans-67.7-25.6-178.7710000112.2T66 M67 C386 R387 V389T66-T69 PolarHBondContact O-N 3.1Å; T66-T69 VanDerWaalsContact O-N 3.07Å; T66-T69 PolarHBondContact O-OG1 3.03Å; M67-T69 VanDerWaalsContact C-N 3.3Å; M67-T69 PolarHBondContact O-N 2.82Å; T69-C386 VanDerWaalsContact CA-O 3.23Å; T69-C386 WeakPolarHBondContact CA-O 3.06Å; T69-C386 WeakPolarHBondContact CG2-O 3.35Å; T69-C386 PolarHBondContact N-O 3.49Å; T69-R387 WeakPolarHBondContact CG2-O 3.2Å; T69-V389 HydrophobicContact CG2-CG2 3.81Å
70A97.3Very high94.8Very high75 Ų7541 Ų4162%0.6222%0.224SC*.THydrogen-bonded Turntrans-96.9-42.6172.200000112.4T66 Y68T66-A70 HydrophobicContact CG2-CB 4.37Å; T66-A70 WeakPolarHBondContact OG1-CB 3.36Å; Y68-A70 PolarHBondContact O-N 2.99Å
71Q96.3Very high94.2Very high143 Ų14342.3 Ų42.367%0.66823%0.23SC*.SBendtrans-151.9122.1-178.3-174.3177.1-2.600110.2Y68Y68-Q71 WeakPolarHBondContact CA-O 3.41Å; Y68-Q71 PolarHBondContact O-N 3.34Å
72P97.5Very high93.8Very high38 Ų3839.7 Ų39.725%0.24722%0.221CC..PPolyproline II helixtrans-66.8168.4177.631-36.2000111.4Q380P72-Q380 HydrophobicContact CB-CG 4.07Å
73W97.8Very high93.6Very high4 Ų440.2 Ų40.22%0.01522%0.224CC..PPolyproline II helixtrans-58.7159.3174.270.792.9000111.6Y68 I75 T345 T349 Q376 I379 Q380 L385Y68-W73 HydrophobicContact CD1-CE3 4.36Å; Y68-W73 HydrophobicContact CD2-CE3 4.28Å; Y68-W73 HydrophobicContact CD2-CZ3 4.5Å; Y68-W73 HydrophobicContact CE1-CB 3.97Å; Y68-W73 HydrophobicContact CE1-CE3 4.15Å; Y68-W73 HydrophobicContact CE2-CE3 4.04Å; Y68-W73 HydrophobicContact CE2-CZ3 4.45Å; Y68-W73 HydrophobicContact CG-CE3 4.42Å; Y68-W73 AromaticContact CZ-CE3 3.97Å; W73-I75 PolarHBondContact O-N 3.01Å; W73-T345 HydrophobicContact CD2-CG2 3.77Å; W73-T345 HydrophobicContact CE3-CG2 3.67Å; W73-T345 HydrophobicContact CH2-CG2 3.44Å; W73-T345 VanDerWaalsContact CH2-CG2 3.44Å; W73-T345 HydrophobicContact CZ2-CG2 3.5Å; W73-T345 HydrophobicContact CZ3-CG2 3.52Å; W73-T349 HydrophobicContact CB-CG2 4.37Å; W73-T349 HydrophobicContact CG-CG2 4.45Å; W73-Q376 HydrophobicContact CZ2-CB 4.27Å; W73-I379 HydrophobicContact CH2-CB 4.03Å; W73-I379 HydrophobicContact CH2-CG2 3.65Å; W73-I379 HydrophobicContact CZ2-CB 4.42Å; W73-I379 HydrophobicContact CZ2-CG2 4.38Å; W73-Q380 HydrophobicContact CD2-CG 4.48Å; W73-Q380 HydrophobicContact CE3-CG 4.36Å; W73-Q380 HydrophobicContact CH2-CB 4.33Å; W73-Q380 HydrophobicContact CH2-CG 3.26Å; W73-Q380 HydrophobicContact CZ2-CG 3.43Å; W73-Q380 VanDerWaalsContact CZ2-CG 3.43Å; W73-Q380 HydrophobicContact CZ3-CG 3.78Å; W73-Q380 PolarHBondContact O-NE2 3.5Å; W73-L385 HydrophobicContact CZ3-CD2 4.41Å
74T95.3Very high93.5Very high42 Ų4240 Ų4026%0.25822%0.224SC..EExtended strand (participates in β ladder)trans-80.1121.9177.1-54.80000110.4R76 K100 Q350 S351 L352T74-R76 PolarHBondContact O-N 3.33Å; T74-K100 HydrophobicContact CG2-CB 4.07Å; T74-Q350 PolarHBondContact N-O 2.73Å; T74-S351 WeakPolarHBondContact O-CA 3.48Å; T74-S351 WeakPolarHBondContact O-CB 3.37Å; T74-L352 PolarHBondContact O-N 3.09Å; T74-L352 VanDerWaalsContact O-N 3.09Å
75I95.7Very high93.4Very high3 Ų341.1 Ų41.12%0.01523%0.232CC..EExtended strand (participates in β ladder)trans-69.4110.4168.3-57.1179.4000107.9W73 K100 R373 Q376 I377W73-I75 PolarHBondContact O-N 3.01Å; I75-K100 PolarHBondContact O-N 3.28Å; I75-R373 HydrophobicContact CG2-CG 4.29Å; I75-Q376 HydrophobicContact CD1-CB 4.02Å; I75-Q376 HydrophobicContact CG1-CB 4.02Å; I75-I377 HydrophobicContact CD1-CG1 3.64Å
76R93.4Very high93.3Very high18 Ų1841.6 Ų41.67%0.06822%0.223CC..  trans-132.586.1-173.7-176.4178.1-71.1-137.5-5.6109.2T74 S151 S153 L352T74-R76 PolarHBondContact O-N 3.33Å; R76-S151 PolarHBondContact NH2-OG 2.94Å; R76-S153 PolarHBondContact NH1-OG 3.42Å; R76-L352 CarbonylContact C-O 3.37Å; R76-L352 PolarHBondContact N-O 3.26Å; R76-L352 VanDerWaalsContact N-O 3.08Å
77Q92.8Very high93.1Very high13 Ų1338.2 Ų38.26%0.06120%0.202CC..  trans-75.7134.3173.9-62.1-58.796.800110.2Q99 S103 T354Q77-Q99 PolarHBondContact O-NE2 3.26Å; Q77-S103 WeakPolarHBondContact O-CB 3.21Å; Q77-T354 PolarHBondContact NE2-O 3.37Å; Q77-T354 PolarHBondContact OE1-OG1 3.41Å
78Y83.7Confident93Very high54 Ų5438.1 Ų38.121%0.21220%0.202CC..  trans-86125.2174.7-172.8-121.2000107.4S103 V104 A105 T155 H353Y78-S103 WeakPolarHBondContact CD2-OG 3.4Å; Y78-V104 VanDerWaalsContact CE2-C 3.47Å; Y78-V104 WeakPolarHBondContact CE2-O 3.45Å; Y78-A105 HydrophobicContact CD1-CB 4.02Å; Y78-A105 HydrophobicContact CD2-CB 4.29Å; Y78-A105 HydrophobicContact CE1-CB 3.44Å; Y78-A105 VanDerWaalsContact CE1-CB 3.44Å; Y78-A105 HydrophobicContact CE2-CB 3.76Å; Y78-A105 HydrophobicContact CG-CB 4.42Å; Y78-A105 VanDerWaalsContact CZ-CA 3.4Å; Y78-A105 VanDerWaalsContact OH-CA 3.32Å; Y78-A105 WeakPolarHBondContact OH-CA 3.41Å; Y78-T155 VanDerWaalsContact CE2-CB 3.41Å; Y78-T155 HydrophobicContact CE2-CG2 4.22Å; Y78-T155 WeakPolarHBondContact CE2-OG1 3.38Å; Y78-T155 WeakPolarHBondContact OH-CB 3.18Å; Y78-T155 VanDerWaalsContact OH-CG2 3.31Å; Y78-T155 WeakPolarHBondContact OH-CG2 3.05Å; Y78-H353 WeakPolarHBondContact CB-CE1 3.48Å; Y78-H353 WeakPolarHBondContact CB-ND1 3.3Å; Y78-H353 PolarHBondContact N-CE1 2.94Å; Y78-H353 VanDerWaalsContact N-CE1 3.33Å; Y78-H353 PolarHBondContact N-ND1 3.25Å
79A84.3Confident92.9Very high10 Ų1039 Ų398%0.08321%0.214CC..BIsolated β-bridgetrans-156.6156.4-172.600000110.8F90 Y91 S103 A105A79-F90 HydrophobicContact CB-CD1 3.76Å; A79-F90 HydrophobicContact CB-CE1 3.47Å; A79-F90 VanDerWaalsContact CB-CE1 3.47Å; A79-Y91 HydrophobicContact CB-CD1 4.33Å; A79-Y91 HydrophobicContact CB-CE1 3.78Å; A79-Y91 WeakPolarHBondContact O-CE1 3.44Å; A79-Y91 PolarHBondContact O-OH 3.04Å; A79-S103 PolarHBondContact N-O 2.86Å; A79-A105 PolarHBondContact O-N 3.02Å
80G76.6Confident92.7Very high6 Ų636 Ų366%0.06219%0.194CC..  trans146.6132.2-178.900000107.2S87 G129G80-S87 WeakPolarHBondContact CA-OG 3.47Å; G80-G129 WeakPolarHBondContact O-CA 3.31Å
81F84.6Confident92.5Very high28 Ų2832.5 Ų32.512%0.12317%0.165CC..  trans-162.9158.3178.755.3-93.8000109.3T83 E86 S87 F90 L363 L470 I472F81-T83 PolarHBondContact O-N 3.04Å; F81-E86 HydrophobicContact CE2-CB 4.47Å; F81-S87 PolarHBondContact N-OG 3.13Å; F81-S87 PolarHBondContact O-OG 2.83Å; F81-F90 HydrophobicContact CE1-CB 4.24Å; F81-F90 HydrophobicContact CE1-CD1 4.06Å; F81-F90 HydrophobicContact CE1-CD2 4.12Å; F81-F90 HydrophobicContact CE1-CE1 4.41Å; F81-F90 HydrophobicContact CE1-CE2 4.49Å; F81-F90 AromaticContact CE1-CG 3.89Å; F81-F90 HydrophobicContact CE1-CG 3.89Å; F81-F90 HydrophobicContact CZ-CB 4.34Å; F81-F90 HydrophobicContact CZ-CD2 4.32Å; F81-F90 HydrophobicContact CZ-CG 4.3Å; F81-L363 HydrophobicContact CB-CD1 3.55Å; F81-L363 HydrophobicContact CG-CD1 4.46Å; F81-L470 HydrophobicContact CD1-CD2 4.32Å; F81-L470 HydrophobicContact CD2-CD2 3.99Å; F81-L470 HydrophobicContact CE1-CD2 4.33Å; F81-L470 HydrophobicContact CE2-CD2 4Å; F81-L470 HydrophobicContact CG-CD2 4.17Å; F81-L470 HydrophobicContact CZ-CD2 4.17Å; F81-I472 HydrophobicContact CB-CD1 3.95Å
82S90.6Very high92.4Very high5 Ų530.2 Ų30.24%0.03515%0.15CC..SBendtrans56.1-122171.5-171.20000111.7E86 G126 G129 A131 V477S82-E86 WeakPolarHBondContact CB-OE2 3.24Å; S82-E86 PolarHBondContact OG-OE2 2.88Å; S82-G126 WeakPolarHBondContact CA-O 3.2Å; S82-G126 PolarHBondContact N-O 2.9Å; S82-G129 PolarHBondContact N-O 3.08Å; S82-A131 PolarHBondContact O-N 3.03Å; S82-V477 WeakPolarHBondContact OG-CG2 3.36Å
83T93.6Very high92.3Very high11 Ų1133.7 Ų33.77%0.06716%0.158CC..  trans-91.3158.2-177.6670000113.2F81 K85 E86 S87 V477F81-T83 PolarHBondContact O-N 3.04Å; T83-K85 PolarHBondContact O-N 3.17Å; T83-E86 PolarHBondContact O-N 3.21Å; T83-E86 WeakPolarHBondContact OG1-CG 3.44Å; T83-E86 PolarHBondContact OG1-N 3.46Å; T83-E86 PolarHBondContact OG1-OE2 2.72Å; T83-S87 WeakPolarHBondContact O-CB 3.36Å; T83-S87 PolarHBondContact O-N 3.27Å; T83-S87 PolarHBondContact O-OG 3.41Å; T83-V477 HydrophobicContact CG2-CG1 4.11Å; T83-V477 HydrophobicContact CG2-CG2 4.11Å
84A95.7Very high91.9Very high4 Ų433.9 Ų33.93%0.03316%0.16CC..Hα-helixtrans-58.3-32.2172.900000113N88 V130 I132 D137 V140 L141A84-N88 VanDerWaalsContact O-CB 3.24Å; A84-N88 WeakPolarHBondContact O-CB 3.37Å; A84-N88 PolarHBondContact O-N 2.94Å; A84-V130 HydrophobicContact CB-CG2 4.03Å; A84-I132 HydrophobicContact CB-CD1 4.49Å; A84-D137 WeakPolarHBondContact CB-O 3.43Å; A84-V140 HydrophobicContact CB-CB 4.11Å; A84-V140 HydrophobicContact CB-CG1 3.93Å; A84-L141 HydrophobicContact CB-CB 4.14Å; A84-L141 HydrophobicContact CB-CD1 4.42Å
85K96.3Very high91.7Very high160 Ų16033.9 Ų33.970%0.69616%0.158SC*.Hα-helixtrans-68.1-45.9178-179-179.8174.5-1720112.1T83 N88 A89 V140T83-K85 PolarHBondContact O-N 3.17Å; K85-N88 PolarHBondContact O-N 3.47Å; K85-A89 PolarHBondContact O-N 2.98Å; K85-V140 HydrophobicContact CB-CG1 4.12Å
86E93.9Very high91.6Very high79 Ų7938.1 Ų38.137%0.36919%0.194SC..Hα-helixtrans-68.9-42.7178.3-71.2175.9131.500111.4F81 S82 T83 N88 A89 F90F81-E86 HydrophobicContact CE2-CB 4.47Å; S82-E86 WeakPolarHBondContact CB-OE2 3.24Å; S82-E86 PolarHBondContact OG-OE2 2.88Å; T83-E86 PolarHBondContact O-N 3.21Å; T83-E86 WeakPolarHBondContact OG1-CG 3.44Å; T83-E86 PolarHBondContact OG1-N 3.46Å; T83-E86 PolarHBondContact OG1-OE2 2.72Å; E86-N88 PolarHBondContact O-N 2.82Å; E86-A89 PolarHBondContact O-N 3.02Å; E86-F90 PolarHBondContact O-N 3.42Å
87S95.2Very high91.5Very high0 Ų039.3 Ų39.30%021%0.207CC..Hα-helixtrans-58.8-45.5173.4-730000112.1G80 F81 T83 A89 F90 Y91G80-S87 WeakPolarHBondContact CA-OG 3.47Å; F81-S87 PolarHBondContact N-OG 3.13Å; F81-S87 PolarHBondContact O-OG 2.83Å; T83-S87 WeakPolarHBondContact O-CB 3.36Å; T83-S87 PolarHBondContact O-N 3.27Å; T83-S87 PolarHBondContact O-OG 3.41Å; S87-A89 PolarHBondContact O-N 2.88Å; S87-F90 WeakPolarHBondContact O-CB 3.4Å; S87-F90 PolarHBondContact O-N 3.31Å; S87-Y91 WeakPolarHBondContact O-CD1 3.49Å; S87-Y91 WeakPolarHBondContact O-CD2 3.31Å; S87-Y91 PolarHBondContact O-N 3.06Å
88N96.8Very high91.2Very high15 Ų1540.3 Ų40.38%0.0822%0.221CC..Hα-helixtrans-58.4-47.3174.3176.7-86.6000111.9A84 K85 E86 F90 Y91 R92 L141 D143A84-N88 VanDerWaalsContact O-CB 3.24Å; A84-N88 WeakPolarHBondContact O-CB 3.37Å; A84-N88 PolarHBondContact O-N 2.94Å; K85-N88 PolarHBondContact O-N 3.47Å; E86-N88 PolarHBondContact O-N 2.82Å; N88-F90 VanDerWaalsContact C-N 3.29Å; N88-F90 PolarHBondContact O-N 2.96Å; N88-Y91 PolarHBondContact O-N 3.38Å; N88-R92 WeakPolarHBondContact O-CG 3.39Å; N88-R92 PolarHBondContact O-N 3.42Å; N88-R92 WeakPolarHBondContact OD1-CD 3.47Å; N88-L141 WeakPolarHBondContact CB-O 3.46Å; N88-L141 PolarHBondContact ND2-O 2.98Å; N88-D143 PolarHBondContact ND2-N 3.13Å; N88-D143 PolarHBondContact ND2-O 3.04Å
89A95.7Very high91.3Very high40 Ų4038.1 Ų38.133%0.33121%0.213SC..Hα-helixtrans-60.2-40.8178.400000111.5K85 E86 S87 R93K85-A89 PolarHBondContact O-N 2.98Å; E86-A89 PolarHBondContact O-N 3.02Å; S87-A89 PolarHBondContact O-N 2.88Å; A89-R93 WeakPolarHBondContact O-CG 3.37Å; A89-R93 PolarHBondContact O-N 3.44Å; A89-R93 VanDerWaalsContact O-N 3.13Å; A89-R93 PolarHBondContact O-NH1 3.18Å
90F93.3Very high91.4Very high9 Ų943.2 Ų43.24%0.03923%0.233CC..Hα-helixtrans-64.4-45.5175.4-173.3-109.4000112.1A79 F81 E86 S87 N88 R92 R93 N94 A369A79-F90 HydrophobicContact CB-CD1 3.76Å; A79-F90 HydrophobicContact CB-CE1 3.47Å; A79-F90 VanDerWaalsContact CB-CE1 3.47Å; F81-F90 HydrophobicContact CE1-CB 4.24Å; F81-F90 HydrophobicContact CE1-CD1 4.06Å; F81-F90 HydrophobicContact CE1-CD2 4.12Å; F81-F90 HydrophobicContact CE1-CE1 4.41Å; F81-F90 HydrophobicContact CE1-CE2 4.49Å; F81-F90 AromaticContact CE1-CG 3.89Å; F81-F90 HydrophobicContact CE1-CG 3.89Å; F81-F90 HydrophobicContact CZ-CB 4.34Å; F81-F90 HydrophobicContact CZ-CD2 4.32Å; F81-F90 HydrophobicContact CZ-CG 4.3Å; E86-F90 PolarHBondContact O-N 3.42Å; S87-F90 WeakPolarHBondContact O-CB 3.4Å; S87-F90 PolarHBondContact O-N 3.31Å; N88-F90 VanDerWaalsContact C-N 3.29Å; N88-F90 PolarHBondContact O-N 2.96Å; F90-R92 PolarHBondContact O-N 3.41Å; F90-R93 PolarHBondContact O-N 3.38Å; F90-N94 WeakPolarHBondContact CD1-ND2 3.45Å; F90-N94 WeakPolarHBondContact CE1-ND2 3.41Å; F90-N94 WeakPolarHBondContact CZ-ND2 3.47Å; F90-N94 PolarHBondContact O-N 2.9Å; F90-A369 HydrophobicContact CZ-CB 3.95Å
91Y93.6Very high91.9Very high1 Ų143 Ų430%0.00423%0.23CC..Hα-helixtrans-57.5-47.3176.1-64.2-16.7000111.9A79 S87 N88 R93 N94 L95 L102 V104 L141 I145A79-Y91 HydrophobicContact CB-CD1 4.33Å; A79-Y91 HydrophobicContact CB-CE1 3.78Å; A79-Y91 WeakPolarHBondContact O-CE1 3.44Å; A79-Y91 PolarHBondContact O-OH 3.04Å; S87-Y91 WeakPolarHBondContact O-CD1 3.49Å; S87-Y91 WeakPolarHBondContact O-CD2 3.31Å; S87-Y91 PolarHBondContact O-N 3.06Å; N88-Y91 PolarHBondContact O-N 3.38Å; Y91-R93 PolarHBondContact O-N 2.87Å; Y91-N94 PolarHBondContact O-N 3.49Å; Y91-L95 WeakPolarHBondContact O-CB 3.25Å; Y91-L95 VanDerWaalsContact O-CG 3.27Å; Y91-L95 WeakPolarHBondContact O-CG 3.43Å; Y91-L95 PolarHBondContact O-N 3.19Å; Y91-L102 HydrophobicContact CD1-CD2 4.37Å; Y91-L102 HydrophobicContact CG-CD2 3.99Å; Y91-V104 HydrophobicContact CE2-CG2 4.31Å; Y91-L141 HydrophobicContact CD2-CD1 4.3Å; Y91-L141 HydrophobicContact CE2-CD1 3.54Å; Y91-L141 HydrophobicContact CE2-CG 4.02Å; Y91-I145 HydrophobicContact CD2-CD1 4.43Å
92R95Very high92.2Very high94 Ų9441.6 Ų41.636%0.35522%0.224SC..Hα-helixtrans-61.9-41.5179.1-68.4171.664.884.6-9.7112N88 F90 A96 Q144 I145N88-R92 WeakPolarHBondContact O-CG 3.39Å; N88-R92 PolarHBondContact O-N 3.42Å; N88-R92 WeakPolarHBondContact OD1-CD 3.47Å; F90-R92 PolarHBondContact O-N 3.41Å; R92-A96 WeakPolarHBondContact O-CB 3.49Å; R92-A96 PolarHBondContact O-N 2.9Å; R92-Q144 PolarHBondContact NH1-O 3.15Å; R92-I145 HydrophobicContact CG-CD1 4.38Å; R92-I145 HydrophobicContact CG-CG1 4.33Å
93R94Very high92.3Very high112 Ų11241.5 Ų41.542%0.42322%0.224SC..Hα-helixtrans-61.3-46174.4-71.5-164.4-55.7-88.820.1111.7A89 F90 Y91 A96 A97 D366A89-R93 WeakPolarHBondContact O-CG 3.37Å; A89-R93 PolarHBondContact O-N 3.44Å; A89-R93 VanDerWaalsContact O-N 3.13Å; A89-R93 PolarHBondContact O-NH1 3.18Å; F90-R93 PolarHBondContact O-N 3.38Å; Y91-R93 PolarHBondContact O-N 2.87Å; R93-A96 PolarHBondContact O-N 3.35Å; R93-A97 WeakPolarHBondContact O-CB 3.39Å; R93-A97 PolarHBondContact O-N 3.15Å; R93-A97 VanDerWaalsContact O-N 3.07Å; R93-D366 IonicContact CZ-OD1 2.72Å; R93-D366 IonicContact CZ-OD2 3.7Å; R93-D366 IonicContact NE-OD1 3.57Å; R93-D366 PolarHBondContact NE-OD1 2.89Å; R93-D366 IonicContact NE-OD2 3.55Å; R93-D366 IonicContact NH2-OD1 3.88Å; R93-D366 PolarHBondContact NH2-OD1 2.96Å; R93-D366 IonicContact NH2-OD2 3.78Å; R93-D366 PolarHBondContact NH2-OD2 3.46Å
94N90Very high92.4Very high7 Ų741 Ų414%0.03722%0.22CC..Hα-helixtrans-70-37.9-178.8-74-26.8000113.5F90 Y91 A96 A97 G98 Q99 R373F90-N94 WeakPolarHBondContact CD1-ND2 3.45Å; F90-N94 WeakPolarHBondContact CE1-ND2 3.41Å; F90-N94 WeakPolarHBondContact CZ-ND2 3.47Å; F90-N94 PolarHBondContact O-N 2.9Å; Y91-N94 PolarHBondContact O-N 3.49Å; N94-A96 VanDerWaalsContact C-N 3.34Å; N94-A97 CarbonylContact O-C 3.45Å; N94-A97 PolarHBondContact O-N 3.47Å; N94-A97 VanDerWaalsContact O-N 3.11Å; N94-G98 PolarHBondContact O-N 3.36Å; N94-Q99 HydrophobicContact CB-CB 4.22Å; N94-Q99 VanDerWaalsContact O-CB 3.27Å; N94-Q99 WeakPolarHBondContact O-CB 3.36Å; N94-Q99 PolarHBondContact O-N 3.03Å; N94-R373 PolarHBondContact OD1-NH1 3.03Å
95L90.8Very high92.4Very high42 Ų4241 Ų4122%0.2222%0.22CC..Hα-helixtrans-59.9-45.9172.3-72.1175000110.8Y91 A97 G98 Q99 L102 M150Y91-L95 WeakPolarHBondContact O-CB 3.25Å; Y91-L95 VanDerWaalsContact O-CG 3.27Å; Y91-L95 WeakPolarHBondContact O-CG 3.43Å; Y91-L95 PolarHBondContact O-N 3.19Å; L95-A97 PolarHBondContact O-N 3.45Å; L95-G98 PolarHBondContact O-N 2.81Å; L95-Q99 HydrophobicContact CD2-CB 4.47Å; L95-Q99 HydrophobicContact CD2-CG 4.46Å; L95-Q99 WeakPolarHBondContact CD2-O 3.42Å; L95-L102 HydrophobicContact CD1-CD1 4.32Å; L95-L102 HydrophobicContact CD1-CD2 3.95Å; L95-L102 HydrophobicContact CD1-CG 4.34Å; L95-L102 HydrophobicContact CD2-CD2 3.88Å; L95-L102 HydrophobicContact CD2-CG 4.32Å; L95-L102 HydrophobicContact CG-CD2 3.86Å; L95-M150 HydrophobicContact CD1-CE 4.04Å; L95-M150 HydrophobicContact CD2-CE 3.44Å; L95-M150 VanDerWaalsContact CD2-CE 3.44Å; L95-M150 HydrophobicContact CG-CE 4.41Å
96A93.4Very high92.4Very high93 Ų9333.5 Ų33.577%0.76919%0.188SC*.Hα-helixtrans-62.2-25.6175.300000112.9R92 R93 N94R92-A96 WeakPolarHBondContact O-CB 3.49Å; R92-A96 PolarHBondContact O-N 2.9Å; R93-A96 PolarHBondContact O-N 3.35Å; N94-A96 VanDerWaalsContact C-N 3.34Å
97A91.1Very high92.6Very high42 Ų4229.7 Ų29.735%0.34717%0.17SC..THydrogen-bonded Turntrans-95.813-179.700000114.7R93 N94 L95 R373R93-A97 WeakPolarHBondContact O-CB 3.39Å; R93-A97 PolarHBondContact O-N 3.15Å; R93-A97 VanDerWaalsContact O-N 3.07Å; N94-A97 CarbonylContact O-C 3.45Å; N94-A97 PolarHBondContact O-N 3.47Å; N94-A97 VanDerWaalsContact O-N 3.11Å; L95-A97 PolarHBondContact O-N 3.45Å; A97-R373 VanDerWaalsContact CB-NH2 3.3Å; A97-R373 PolarHBondContact O-NE 3.48Å
98G87.1Confident92.7Very high35 Ų3530.3 Ų30.336%0.36117%0.173SC..THydrogen-bonded Turntrans108.3-0.2170.400000116.2N94 L95N94-G98 PolarHBondContact O-N 3.36Å; L95-G98 PolarHBondContact O-N 2.81Å
99Q85.4Confident92.8Very high7 Ų729.6 Ų29.63%0.03317%0.17CC..  trans-65136.4169.7-178.2166.7-10.400110.2Q77 N94 L95 G101Q77-Q99 PolarHBondContact O-NE2 3.26Å; N94-Q99 HydrophobicContact CB-CB 4.22Å; N94-Q99 VanDerWaalsContact O-CB 3.27Å; N94-Q99 WeakPolarHBondContact O-CB 3.36Å; N94-Q99 PolarHBondContact O-N 3.03Å; L95-Q99 HydrophobicContact CD2-CB 4.47Å; L95-Q99 HydrophobicContact CD2-CG 4.46Å; L95-Q99 WeakPolarHBondContact CD2-O 3.42Å; Q99-G101 VanDerWaalsContact CG-O 3.3Å; Q99-G101 WeakPolarHBondContact CG-O 3.35Å; Q99-G101 PolarHBondContact NE2-O 3.41Å
100K86.7Confident92.9Very high118 Ų11827.7 Ų27.751%0.51315%0.154SC..  trans-103.6-33.2-174.5-68.7-176.3-179.1169.90114T74 I75T74-K100 HydrophobicContact CG2-CB 4.07Å; I75-K100 PolarHBondContact O-N 3.28Å
101G86.7Confident93.2Very high0 Ų027.4 Ų27.40%015%0.153CC..SBendtrans-127.7147.8177.200000111Q99Q99-G101 VanDerWaalsContact CG-O 3.3Å; Q99-G101 WeakPolarHBondContact CG-O 3.35Å; Q99-G101 PolarHBondContact NE2-O 3.41Å
102L91.4Very high93.4Very high0 Ų027.4 Ų27.40%015%0.153CC..EExtended strand (participates in β ladder)trans-88.7151.2176.1-65.2177.2000110.4Y91 L95 F142 I145 M150 S151 S153Y91-L102 HydrophobicContact CD1-CD2 4.37Å; Y91-L102 HydrophobicContact CG-CD2 3.99Å; L95-L102 HydrophobicContact CD1-CD1 4.32Å; L95-L102 HydrophobicContact CD1-CD2 3.95Å; L95-L102 HydrophobicContact CD1-CG 4.34Å; L95-L102 HydrophobicContact CD2-CD2 3.88Å; L95-L102 HydrophobicContact CD2-CG 4.32Å; L95-L102 HydrophobicContact CG-CD2 3.86Å; L102-F142 HydrophobicContact CD1-CE1 4.41Å; L102-I145 HydrophobicContact CD1-CD1 4Å; L102-I145 HydrophobicContact CD1-CG2 3.78Å; L102-M150 HydrophobicContact CD1-CE 4.48Å; L102-M150 HydrophobicContact CG-CE 4.11Å; L102-S151 PolarHBondContact N-O 3.06Å; L102-S153 PolarHBondContact O-N 3.06Å
103S92.1Very high93.5Very high3 Ų323 Ų232%0.02114%0.136CC..EExtended strand (participates in β ladder)trans-145.2112174.4-164.80000108.8Q77 Y78 A79 S153Q77-S103 WeakPolarHBondContact O-CB 3.21Å; Y78-S103 WeakPolarHBondContact CD2-OG 3.4Å; A79-S103 PolarHBondContact N-O 2.86Å; S103-S153 CarbonylContact C-O 3.48Å; S103-S153 VanDerWaalsContact CA-O 3.31Å; S103-S153 WeakPolarHBondContact CA-O 3.35Å; S103-S153 VanDerWaalsContact OG-CB 3.22Å; S103-S153 WeakPolarHBondContact OG-CB 3.44Å
104V96Very high93.8Very high0 Ų018.8 Ų18.80%012%0.12CC..EExtended strand (participates in β ladder)trans-91.6121.8-168.3-177.10000111.1Y78 Y91 F106 V130 L141 F142 V152 S153 M154 T155Y78-V104 VanDerWaalsContact CE2-C 3.47Å; Y78-V104 WeakPolarHBondContact CE2-O 3.45Å; Y91-V104 HydrophobicContact CE2-CG2 4.31Å; V104-F106 HydrophobicContact CB-CE2 4.11Å; V104-F106 HydrophobicContact CB-CZ 3.95Å; V104-F106 HydrophobicContact CG1-CD1 4.04Å; V104-F106 HydrophobicContact CG1-CD2 4.3Å; V104-F106 HydrophobicContact CG1-CE1 3.55Å; V104-F106 HydrophobicContact CG1-CE2 3.85Å; V104-F106 HydrophobicContact CG1-CG 4.4Å; V104-F106 HydrophobicContact CG1-CZ 3.45Å; V104-F106 VanDerWaalsContact CG1-CZ 3.45Å; V104-V130 HydrophobicContact CG1-CG1 3.92Å; V104-L141 HydrophobicContact CG1-CD2 3.84Å; V104-L141 HydrophobicContact CG2-CD2 4.3Å; V104-F142 HydrophobicContact CG2-CE1 4.33Å; V104-F142 HydrophobicContact CG2-CZ 4.02Å; V104-V152 HydrophobicContact CG2-CG1 4.14Å; V104-S153 PolarHBondContact N-O 2.96Å; V104-M154 HydrophobicContact CB-CG 4.4Å; V104-M154 HydrophobicContact CG2-CG 4.42Å; V104-T155 PolarHBondContact O-N 3.15Å
105A95.2Very high94.2Very high4 Ų418.9 Ų18.93%0.03312%0.121CC..PPolyproline II helixtrans-94122.7168.800000110.9Y78 A79 G129 V130Y78-A105 HydrophobicContact CD1-CB 4.02Å; Y78-A105 HydrophobicContact CD2-CB 4.29Å; Y78-A105 HydrophobicContact CE1-CB 3.44Å; Y78-A105 VanDerWaalsContact CE1-CB 3.44Å; Y78-A105 HydrophobicContact CE2-CB 3.76Å; Y78-A105 HydrophobicContact CG-CB 4.42Å; Y78-A105 VanDerWaalsContact CZ-CA 3.4Å; Y78-A105 VanDerWaalsContact OH-CA 3.32Å; Y78-A105 WeakPolarHBondContact OH-CA 3.41Å; A79-A105 PolarHBondContact O-N 3.02Å; A105-G129 CarbonylContact O-C 3.55Å; A105-G129 WeakPolarHBondContact O-CA 3.38Å; A105-V130 WeakPolarHBondContact O-CG1 3.29Å; A105-V130 PolarHBondContact O-N 3.43Å
106F97.8Very high94.5Very high2 Ų216.9 Ų16.91%0.00911%0.111CC..BIsolated β-bridgetrans-101.8152.7179.8-57.5-83.6000110.4V104 T110 H111 V130 I132 M138 M154 T155 M156 V163V104-F106 HydrophobicContact CB-CE2 4.11Å; V104-F106 HydrophobicContact CB-CZ 3.95Å; V104-F106 HydrophobicContact CG1-CD1 4.04Å; V104-F106 HydrophobicContact CG1-CD2 4.3Å; V104-F106 HydrophobicContact CG1-CE1 3.55Å; V104-F106 HydrophobicContact CG1-CE2 3.85Å; V104-F106 HydrophobicContact CG1-CG 4.4Å; V104-F106 HydrophobicContact CG1-CZ 3.45Å; V104-F106 VanDerWaalsContact CG1-CZ 3.45Å; F106-T110 HydrophobicContact CB-CG2 3.95Å; F106-T110 HydrophobicContact CD1-CG2 3.95Å; F106-T110 HydrophobicContact CG-CG2 4.17Å; F106-H111 PolarHBondContact O-CD2 3.15Å; F106-H111 VanDerWaalsContact O-CD2 3.32Å; F106-V130 WeakPolarHBondContact CA-O 3.42Å; F106-V130 HydrophobicContact CD1-CG1 3.93Å; F106-V130 HydrophobicContact CE1-CG1 4.39Å; F106-I132 HydrophobicContact CD1-CG1 3.85Å; F106-I132 HydrophobicContact CE1-CG1 3.97Å; F106-M138 HydrophobicContact CE1-CE 4.21Å; F106-M154 HydrophobicContact CE2-CB 3.91Å; F106-M154 HydrophobicContact CE2-CG 4.3Å; F106-M154 HydrophobicContact CZ-CB 4.15Å; F106-M154 HydrophobicContact CZ-CG 4.06Å; F106-M154 HydrophobicContact CZ-SD 4.32Å; F106-T155 WeakPolarHBondContact CD2-O 3.46Å; F106-M156 HydrophobicContact CB-CE 3.49Å; F106-M156 VanDerWaalsContact CB-CE 3.49Å; F106-M156 HydrophobicContact CD1-CE 4.32Å; F106-M156 HydrophobicContact CD2-CB 4.16Å; F106-M156 HydrophobicContact CD2-CE 3.42Å; F106-M156 VanDerWaalsContact CD2-CE 3.42Å; F106-M156 HydrophobicContact CE2-CB 4.03Å; F106-M156 HydrophobicContact CE2-CE 4.19Å; F106-M156 HydrophobicContact CG-CE 3.48Å; F106-M156 VanDerWaalsContact CG-CE 3.48Å; F106-V163 HydrophobicContact CE1-CG1 3.94Å; F106-V163 HydrophobicContact CE2-CG1 4.05Å; F106-V163 HydrophobicContact CZ-CG1 3.52Å
107D97.3Very high94.7Very high0 Ų015 Ų150%09%0.088CC..PPolyproline II helixtrans-69.2168.9173.975.23.9000112.5A109 T110 H111 V125 G126 V130 A131D107-A109 VanDerWaalsContact C-N 3.3Å; D107-A109 PolarHBondContact O-N 3.43Å; D107-A109 PolarHBondContact OD1-N 3.43Å; D107-T110 PolarHBondContact O-N 2.69Å; D107-T110 WeakPolarHBondContact OD1-CB 3.29Å; D107-T110 PolarHBondContact OD1-N 3.25Å; D107-T110 PolarHBondContact OD1-OG1 3.03Å; D107-H111 PolarHBondContact O-CD2 2.92Å; D107-H111 VanDerWaalsContact O-CD2 3.25Å; D107-H111 PolarHBondContact O-N 2.94Å; D107-V125 WeakPolarHBondContact OD2-CA 3.38Å; D107-G126 PolarHBondContact OD2-N 3.16Å; D107-V130 PolarHBondContact N-O 3.4Å; D107-A131 WeakPolarHBondContact OD2-CA 3.49Å; D107-A131 VanDerWaalsContact OD2-CB 3.27Å; D107-A131 WeakPolarHBondContact OD2-CB 3.45Å
108L97.7Very high95.1Very high13 Ų1315 Ų157%0.0688%0.082CC..Hα-helixtrans-73.1-23.7-175.4-66.7172.2000113R112 D124 A128 T198 Q594 A645L108-R112 WeakPolarHBondContact O-CG 3.17Å; L108-R112 PolarHBondContact O-N 3.16Å; L108-D124 HydrophobicContact CB-CB 4.37Å; L108-A128 HydrophobicContact CD1-CB 4.41Å; L108-A128 HydrophobicContact CG-CB 4.03Å; L108-T198 HydrophobicContact CD2-CG2 4.27Å; L108-Q594 HydrophobicContact CB-CB 3.55Å; L108-Q594 HydrophobicContact CD1-CB 4.36Å; L108-A645 HydrophobicContact CD1-CB 3.52Å
109A97.9Very high95.4Very high0 Ų018.5 Ų18.50%010%0.098CC..Hα-helixtrans-63.4-54.8171.800000110.7D107 H111 R112 G113 Y114 V121D107-A109 VanDerWaalsContact C-N 3.3Å; D107-A109 PolarHBondContact O-N 3.43Å; D107-A109 PolarHBondContact OD1-N 3.43Å; A109-H111 VanDerWaalsContact C-N 3.3Å; A109-H111 PolarHBondContact O-N 3.49Å; A109-R112 CarbonylContact O-C 3.52Å; A109-R112 PolarHBondContact O-N 3.06Å; A109-R112 VanDerWaalsContact O-N 3.1Å; A109-G113 PolarHBondContact O-N 3.12Å; A109-Y114 CarbonylContact C-O 3.56Å; A109-Y114 PolarHBondContact O-N 3.05Å; A109-V121 HydrophobicContact CB-CB 3.8Å; A109-V121 HydrophobicContact CB-CG1 4.07Å; A109-V121 HydrophobicContact CB-CG2 3.74Å
110T98.6Very high95.9Very high0 Ų022 Ų220%011%0.111CC..Hα-helixtrans-54.6-47.7175.4-54.70000110.2F106 D107 R112 G113 I132 M156 A159 V163 L528F106-T110 HydrophobicContact CB-CG2 3.95Å; F106-T110 HydrophobicContact CD1-CG2 3.95Å; F106-T110 HydrophobicContact CG-CG2 4.17Å; D107-T110 PolarHBondContact O-N 2.69Å; D107-T110 WeakPolarHBondContact OD1-CB 3.29Å; D107-T110 PolarHBondContact OD1-N 3.25Å; D107-T110 PolarHBondContact OD1-OG1 3.03Å; T110-R112 PolarHBondContact O-N 2.92Å; T110-G113 PolarHBondContact O-N 2.69Å; T110-I132 HydrophobicContact CG2-CB 4.02Å; T110-I132 PolarHBondContact OG1-N 3.38Å; T110-I132 VanDerWaalsContact OG1-N 3.13Å; T110-M156 HydrophobicContact CG2-CE 3.81Å; T110-A159 WeakPolarHBondContact O-CB 3.29Å; T110-V163 HydrophobicContact CG2-CG2 3.94Å; T110-L528 HydrophobicContact CG2-CD1 3.67Å
111H98.6Very high96.4Very high3 Ų316.3 Ų16.31%0.0149%0.086CC..Hα-helixtrans-54.2-38.2-180-95.9-68000113.8F106 D107 A109 T155 M156 A159 R196 T198F106-H111 PolarHBondContact O-CD2 3.15Å; F106-H111 VanDerWaalsContact O-CD2 3.32Å; D107-H111 PolarHBondContact O-CD2 2.92Å; D107-H111 VanDerWaalsContact O-CD2 3.25Å; D107-H111 PolarHBondContact O-N 2.94Å; A109-H111 VanDerWaalsContact C-N 3.3Å; A109-H111 PolarHBondContact O-N 3.49Å; H111-T155 PolarHBondContact CE1-O 3.13Å; H111-T155 PolarHBondContact NE2-O 2.97Å; H111-M156 HydrophobicContact CB-CE 4.33Å; H111-M156 HydrophobicContact CB-SD 4.47Å; H111-A159 PolarHBondContact O-N 3.37Å; H111-A159 VanDerWaalsContact O-N 3.09Å; H111-R196 PolarHBondContact CE1-NH1 3.2Å; H111-R196 PolarHBondContact CE1-NH2 3.48Å; H111-R196 PolarHBondContact ND1-NH1 3.15Å; H111-R196 PolarHBondContact NE2-NH2 3.26Å; H111-T198 HydrophobicContact CB-CG2 4.18Å
112R98.3Very high96.6Very high1 Ų117.1 Ų17.10%0.0049%0.093CC..THydrogen-bonded Turntrans-103.313.5-172-60.9-156.669.7-125.53.9113.6L108 A109 T110 Y114 Y199 I200 R541 F621L108-R112 WeakPolarHBondContact O-CG 3.17Å; L108-R112 PolarHBondContact O-N 3.16Å; A109-R112 CarbonylContact O-C 3.52Å; A109-R112 PolarHBondContact O-N 3.06Å; A109-R112 VanDerWaalsContact O-N 3.1Å; T110-R112 PolarHBondContact O-N 2.92Å; R112-Y114 HydrophobicContact CB-CD2 4.15Å; R112-Y114 HydrophobicContact CB-CE2 4.36Å; R112-Y199 PolarHBondContact NE-O 2.95Å; R112-Y199 PolarHBondContact NH2-O 3.04Å; R112-I200 WeakPolarHBondContact O-CD1 3.12Å; R112-I200 WeakPolarHBondContact O-CG1 3.28Å; R112-R541 PolarHBondContact O-NH2 2.87Å; R112-F621 VanDerWaalsContact CZ-CG 3.48Å; R112-F621 VanDerWaalsContact NH1-CD2 3.31Å
113G98.5Very high96.6Very high1 Ų117.2 Ų17.21%0.019%0.094CC..THydrogen-bonded Turntrans77.529.7171.700000113.3A109 T110 L528 G529 S532A109-G113 PolarHBondContact O-N 3.12Å; T110-G113 PolarHBondContact O-N 2.69Å; G113-L528 VanDerWaalsContact C-CD2 3.46Å; G113-L528 VanDerWaalsContact CA-CD2 3.45Å; G113-G529 WeakPolarHBondContact O-CA 3.32Å; G113-S532 WeakPolarHBondContact CA-OG 3.43Å
114Y98.6Very high96.7Very high23 Ų2317.1 Ų17.19%0.099%0.093CC..  trans-113.6135.9177.8-67.2-53.9000111.4A109 R112 N118 V121 R541A109-Y114 CarbonylContact C-O 3.56Å; A109-Y114 PolarHBondContact O-N 3.05Å; R112-Y114 HydrophobicContact CB-CD2 4.15Å; R112-Y114 HydrophobicContact CB-CE2 4.36Å; Y114-N118 HydrophobicContact CD1-CB 4.48Å; Y114-N118 VanDerWaalsContact CD1-ND2 3.35Å; Y114-N118 WeakPolarHBondContact CD1-ND2 3.4Å; Y114-V121 HydrophobicContact CD2-CG1 3.46Å; Y114-V121 VanDerWaalsContact CD2-CG1 3.46Å; Y114-V121 HydrophobicContact CE2-CG1 4.31Å; Y114-V121 HydrophobicContact CG-CG1 3.83Å; Y114-R541 VanDerWaalsContact CE2-NH2 3.27Å; Y114-R541 PolarHBondContact OH-NE 3.43Å; Y114-R541 PolarHBondContact OH-NH1 2.94Å; Y114-R541 PolarHBondContact OH-NH2 3.21Å
115D98.7Very high96.8Very high10 Ų1017.1 Ų17.15%0.0539%0.093CC..  trans-69151.5165.8-70.9-13.7000110.5D117 N118 D133 L485 R489 T527 L528 G529D115-D117 VanDerWaalsContact CB-OD1 3.24Å; D115-D117 WeakPolarHBondContact CB-OD1 3.14Å; D115-D117 PolarHBondContact O-N 2.58Å; D115-D117 VanDerWaalsContact O-N 3.09Å; D115-N118 VanDerWaalsContact O-CB 3.24Å; D115-N118 WeakPolarHBondContact O-CB 3.23Å; D115-N118 PolarHBondContact O-N 3.41Å; D115-D133 VanDerWaalsContact CA-OD1 3.31Å; D115-D133 WeakPolarHBondContact CA-OD1 3.45Å; D115-L485 HydrophobicContact CB-CD1 4.05Å; D115-R489 IonicContact OD2-NH2 3.26Å; D115-R489 PolarHBondContact OD2-NH2 3.29Å; D115-T527 VanDerWaalsContact CG-OG1 3.28Å; D115-T527 VanDerWaalsContact OD1-CB 3.27Å; D115-T527 WeakPolarHBondContact OD1-CB 3.23Å; D115-T527 PolarHBondContact OD1-OG1 3.49Å; D115-T527 WeakPolarHBondContact OD2-CB 3.22Å; D115-T527 PolarHBondContact OD2-OG1 3.22Å; D115-L528 PolarHBondContact OD1-N 3.4Å; D115-G529 WeakPolarHBondContact OD1-CA 3.43Å; D115-G529 PolarHBondContact OD1-N 3.38Å
116S98.3Very high96.7Very high0 Ų017 Ų170%09%0.092CC..THydrogen-bonded Turntrans-59.7-18.3180-61.80000115.1D133 Q481S116-D133 VanDerWaalsContact CB-OD2 3.25Å; S116-D133 WeakPolarHBondContact CB-OD2 3.39Å; S116-D133 PolarHBondContact N-OD1 2.66Å; S116-D133 VanDerWaalsContact OG-CG 3.28Å; S116-D133 PolarHBondContact OG-OD1 3.25Å; S116-D133 VanDerWaalsContact OG-OD1 3.05Å; S116-D133 PolarHBondContact OG-OD2 3.44Å; S116-Q481 VanDerWaalsContact CB-CB 3.5Å; S116-Q481 WeakPolarHBondContact OG-CB 3.2Å
117D97.9Very high96.4Very high54 Ų5417.9 Ų17.929%0.28910%0.095SC..THydrogen-bonded Turntrans-87.4-5.4176.571.4-22.6000113.5D115 I482 L485 R489D115-D117 VanDerWaalsContact CB-OD1 3.24Å; D115-D117 WeakPolarHBondContact CB-OD1 3.14Å; D115-D117 PolarHBondContact O-N 2.58Å; D115-D117 VanDerWaalsContact O-N 3.09Å; D117-I482 HydrophobicContact CB-CG1 3.85Å; D117-L485 HydrophobicContact CB-CD1 4.07Å; D117-R489 IonicContact OD1-NH2 3.72Å; D117-R489 PolarHBondContact OD1-NH2 2.97Å; D117-R489 IonicContact OD2-CZ 3.87Å; D117-R489 IonicContact OD2-NH1 3.85Å; D117-R489 PolarHBondContact OD2-NH1 3.33Å; D117-R489 IonicContact OD2-NH2 2.82Å; D117-R489 PolarHBondContact OD2-NH2 3.05Å; D117-R489 VanDerWaalsContact OD2-NH2 3.1Å
118N97.6Very high96.1Very high42 Ų4219.7 Ų19.723%0.22511%0.111CC..  trans-68.3128.4178.2-169.6-53.8000110.9Y114 D115 R120 V121Y114-N118 HydrophobicContact CD1-CB 4.48Å; Y114-N118 VanDerWaalsContact CD1-ND2 3.35Å; Y114-N118 WeakPolarHBondContact CD1-ND2 3.4Å; D115-N118 VanDerWaalsContact O-CB 3.24Å; D115-N118 WeakPolarHBondContact O-CB 3.23Å; D115-N118 PolarHBondContact O-N 3.41Å; N118-R120 PolarHBondContact O-N 3.37Å; N118-R120 VanDerWaalsContact O-N 3.13Å; N118-R120 WeakPolarHBondContact OD1-CB 3.19Å; N118-R120 PolarHBondContact OD1-N 3.11Å; N118-V121 HydrophobicContact CB-CG2 4.11Å; N118-V121 WeakPolarHBondContact O-CG2 3.32Å; N118-V121 PolarHBondContact O-N 3.31Å
119P94.6Very high96Very high108 Ų10819.1 Ų19.170%0.70111%0.108SC*.G310 helixtrans-61.7-24.7-177.223.7-34.2000113.8V121P119-V121 PolarHBondContact O-N 2.91Å
120R95.5Very high95.9Very high79 Ų7919.1 Ų19.130%0.29811%0.108SC..G310 helixtrans-74.6-9.9-178.9-61.2-164.17178.4-1.4114.6N118 Q594 F621 T623 E626N118-R120 PolarHBondContact O-N 3.37Å; N118-R120 VanDerWaalsContact O-N 3.13Å; N118-R120 WeakPolarHBondContact OD1-CB 3.19Å; N118-R120 PolarHBondContact OD1-N 3.11Å; R120-Q594 PolarHBondContact O-NE2 2.85Å; R120-F621 PolarHBondContact NH2-O 2.85Å; R120-T623 VanDerWaalsContact NH1-CG2 3.25Å; R120-E626 IonicContact CZ-OE1 2.87Å; R120-E626 IonicContact CZ-OE2 3.42Å; R120-E626 IonicContact NH1-OE1 3.3Å; R120-E626 PolarHBondContact NH1-OE1 3.25Å; R120-E626 IonicContact NH1-OE2 3.39Å; R120-E626 IonicContact NH2-OE1 3.98Å; R120-E626 PolarHBondContact NH2-OE1 2.87Å; R120-E626 IonicContact NH2-OE2 2.85Å; R120-E626 PolarHBondContact NH2-OE2 2.86Å
121V96.3Very high95.9Very high0 Ų019.1 Ų19.10%011%0.108CC..G310 helixtrans-121.411.8-175.8-52.80000113A109 Y114 N118 P119 G123 D124 V125 Q594A109-V121 HydrophobicContact CB-CB 3.8Å; A109-V121 HydrophobicContact CB-CG1 4.07Å; A109-V121 HydrophobicContact CB-CG2 3.74Å; Y114-V121 HydrophobicContact CD2-CG1 3.46Å; Y114-V121 VanDerWaalsContact CD2-CG1 3.46Å; Y114-V121 HydrophobicContact CE2-CG1 4.31Å; Y114-V121 HydrophobicContact CG-CG1 3.83Å; N118-V121 HydrophobicContact CB-CG2 4.11Å; N118-V121 WeakPolarHBondContact O-CG2 3.32Å; N118-V121 PolarHBondContact O-N 3.31Å; P119-V121 PolarHBondContact O-N 2.91Å; V121-G123 PolarHBondContact O-N 2.93Å; V121-D124 HydrophobicContact CB-CB 4.42Å; V121-D124 PolarHBondContact O-N 3.45Å; V121-V125 HydrophobicContact CG2-CG2 4.07Å; V121-V125 WeakPolarHBondContact O-CG2 3.27Å; V121-V125 PolarHBondContact O-N 3.39Å; V121-Q594 HydrophobicContact CB-CG 4.31Å; V121-Q594 HydrophobicContact CG1-CG 3.6Å
122A91.3Very high95.9Very high17 Ų1719 Ų1914%0.1411%0.107CC..THydrogen-bonded Turntrans-52.1-35-175.200000114.4N474A122-N474 PolarHBondContact O-ND2 2.86Å
123G91.7Very high95.9Very high1 Ų119 Ų191%0.0111%0.107CC..THydrogen-bonded Turntrans-87.5-9.7177.800000114.9V121 K127V121-G123 PolarHBondContact O-N 2.93Å; G123-K127 WeakPolarHBondContact O-CG 3.44Å
124D95.4Very high95.9Very high2 Ų219 Ų191%0.01111%0.107CC..THydrogen-bonded Turntrans-104.8-21.3-169.9-57.8-78.2000113.4L108 V121 G126 K127 Q594L108-D124 HydrophobicContact CB-CB 4.37Å; V121-D124 HydrophobicContact CB-CB 4.42Å; V121-D124 PolarHBondContact O-N 3.45Å; D124-G126 PolarHBondContact O-N 3.07Å; D124-K127 PolarHBondContact O-N 2.99Å; D124-Q594 HydrophobicContact CB-CB 4.33Å; D124-Q594 HydrophobicContact CB-CG 4.31Å; D124-Q594 VanDerWaalsContact CG-N 3.34Å; D124-Q594 PolarHBondContact OD1-N 2.87Å; D124-Q594 WeakPolarHBondContact OD2-CG 3Å; D124-Q594 PolarHBondContact OD2-N 2.87Å
125V96.3Very high95.9Very high0 Ų017.9 Ų17.90%010%0.103CC..THydrogen-bonded Turntrans-56.9121.2-176.4-178.10000111.3D107 V121 K127 A131 V477 R478D107-V125 WeakPolarHBondContact OD2-CA 3.38Å; V121-V125 HydrophobicContact CG2-CG2 4.07Å; V121-V125 WeakPolarHBondContact O-CG2 3.27Å; V121-V125 PolarHBondContact O-N 3.39Å; V125-K127 PolarHBondContact O-N 3.43Å; V125-A131 HydrophobicContact CG1-CB 4Å; V125-V477 HydrophobicContact CG1-CG1 4.19Å; V125-R478 HydrophobicContact CB-CB 4.26Å; V125-R478 HydrophobicContact CG1-CB 4.23Å; V125-R478 HydrophobicContact CG2-CG 4.38Å
126G94Very high95.9Very high0 Ų019.2 Ų19.20%011%0.109CC..THydrogen-bonded Turntrans70.10.8176.600000116.3S82 D107 D124 G129S82-G126 WeakPolarHBondContact CA-O 3.2Å; S82-G126 PolarHBondContact N-O 2.9Å; D107-G126 PolarHBondContact OD2-N 3.16Å; D124-G126 PolarHBondContact O-N 3.07Å; G126-G129 CarbonylContact C-O 3.49Å; G126-G129 VanDerWaalsContact C-O 3.31Å; G126-G129 WeakPolarHBondContact CA-O 3.32Å
127K91.9Very high95.9Very high21 Ų2119.8 Ų19.89%0.09111%0.111CC..THydrogen-bonded Turntrans-75.2-60-175.5-73.3-62.2-158.4-172.40112.6G123 D124 V125 G129 I472 N474 A646G123-K127 WeakPolarHBondContact O-CG 3.44Å; D124-K127 PolarHBondContact O-N 2.99Å; V125-K127 PolarHBondContact O-N 3.43Å; K127-G129 VanDerWaalsContact C-N 3.33Å; K127-I472 HydrophobicContact CD-CB 4.42Å; K127-I472 HydrophobicContact CD-CG2 4.49Å; K127-I472 PolarHBondContact NZ-O 3.08Å; K127-I472 WeakPolarHBondContact O-CD1 3.32Å; K127-N474 HydrophobicContact CD-CB 3.97Å; K127-N474 HydrophobicContact CG-CB 4.21Å; K127-N474 PolarHBondContact NZ-OD1 3.01Å; K127-A646 HydrophobicContact CD-CB 4.28Å; K127-A646 WeakPolarHBondContact CE-O 3.33Å
128A91Very high96Very high39 Ų3917.2 Ų17.232%0.32210%0.098SC..SBendtrans-83.6-8.8-174.600000113.9L108L108-A128 HydrophobicContact CD1-CB 4.41Å; L108-A128 HydrophobicContact CG-CB 4.03Å
129G95Very high96Very high0 Ų018.1 Ų18.10%010%0.1CC..SBendtrans179.9-169-174.800000111.9G80 S82 A105 G126 K127G80-G129 WeakPolarHBondContact O-CA 3.31Å; S82-G129 PolarHBondContact N-O 3.08Å; A105-G129 CarbonylContact O-C 3.55Å; A105-G129 WeakPolarHBondContact O-CA 3.38Å; G126-G129 CarbonylContact C-O 3.49Å; G126-G129 VanDerWaalsContact C-O 3.31Å; G126-G129 WeakPolarHBondContact CA-O 3.32Å; K127-G129 VanDerWaalsContact C-N 3.33Å
130V96.7Very high96.2Very high0 Ų016 Ų160%09%0.085CC..BIsolated β-bridgetrans-73.4134.6175.566.60000111.1A84 V104 A105 F106 D107 I132 L141A84-V130 HydrophobicContact CB-CG2 4.03Å; V104-V130 HydrophobicContact CG1-CG1 3.92Å; A105-V130 WeakPolarHBondContact O-CG1 3.29Å; A105-V130 PolarHBondContact O-N 3.43Å; F106-V130 WeakPolarHBondContact CA-O 3.42Å; F106-V130 HydrophobicContact CD1-CG1 3.93Å; F106-V130 HydrophobicContact CE1-CG1 4.39Å; D107-V130 PolarHBondContact N-O 3.4Å; V130-I132 HydrophobicContact CG1-CD1 4.26Å; V130-I132 HydrophobicContact CG1-CG1 4.02Å; V130-I132 HydrophobicContact CG2-CD1 4.07Å; V130-I132 HydrophobicContact CG2-CG1 4.45Å; V130-L141 HydrophobicContact CG1-CD1 4.45Å; V130-L141 HydrophobicContact CG1-CD2 4.29Å; V130-L141 HydrophobicContact CG2-CD1 4.26Å
131A97.7Very high96.3Very high0 Ų012.3 Ų12.30%07%0.071CC..  trans-77.8126.1169.700000110.9S82 D107 V125 Q481S82-A131 PolarHBondContact O-N 3.03Å; D107-A131 WeakPolarHBondContact OD2-CA 3.49Å; D107-A131 VanDerWaalsContact OD2-CB 3.27Å; D107-A131 WeakPolarHBondContact OD2-CB 3.45Å; V125-A131 HydrophobicContact CG1-CB 4Å; A131-Q481 HydrophobicContact CB-CG 3.96Å; A131-Q481 PolarHBondContact O-NE2 2.72Å
132I98.6Very high96.4Very high0 Ų012.3 Ų12.30%07%0.071CC..  trans-131.9112.7178.5-60.6-65.9000109.1A84 F106 T110 V130 D137 M138 L141 F166 L528A84-I132 HydrophobicContact CB-CD1 4.49Å; F106-I132 HydrophobicContact CD1-CG1 3.85Å; F106-I132 HydrophobicContact CE1-CG1 3.97Å; T110-I132 HydrophobicContact CG2-CB 4.02Å; T110-I132 PolarHBondContact OG1-N 3.38Å; T110-I132 VanDerWaalsContact OG1-N 3.13Å; V130-I132 HydrophobicContact CG1-CD1 4.26Å; V130-I132 HydrophobicContact CG1-CG1 4.02Å; V130-I132 HydrophobicContact CG2-CD1 4.07Å; V130-I132 HydrophobicContact CG2-CG1 4.45Å; I132-D137 HydrophobicContact CD1-CB 3.69Å; I132-D137 HydrophobicContact CG2-CB 4.42Å; I132-M138 HydrophobicContact CG2-CE 4.11Å; I132-L141 HydrophobicContact CD1-CD2 4.33Å; I132-F166 HydrophobicContact CG2-CD2 3.85Å; I132-F166 HydrophobicContact CG2-CE2 4.3Å; I132-L528 WeakPolarHBondContact O-CD1 3.42Å
133D98.8Very high96.7Very high1 Ų115.3 Ų15.31%0.0058%0.084CC..  trans-107.7-27.9-180-62.4-50000111.9D115 S116 D137 Q481 L485 T527 L528D115-D133 VanDerWaalsContact CA-OD1 3.31Å; D115-D133 WeakPolarHBondContact CA-OD1 3.45Å; S116-D133 VanDerWaalsContact CB-OD2 3.25Å; S116-D133 WeakPolarHBondContact CB-OD2 3.39Å; S116-D133 PolarHBondContact N-OD1 2.66Å; S116-D133 VanDerWaalsContact OG-CG 3.28Å; S116-D133 PolarHBondContact OG-OD1 3.25Å; S116-D133 VanDerWaalsContact OG-OD1 3.05Å; S116-D133 PolarHBondContact OG-OD2 3.44Å; D133-D137 PolarHBondContact N-OD2 2.84Å; D133-Q481 PolarHBondContact OD2-OE1 3.04Å; D133-L485 HydrophobicContact CB-CD1 4.25Å; D133-L485 HydrophobicContact CB-CD2 3.8Å; D133-L485 HydrophobicContact CB-CG 4.07Å; D133-T527 CarbonylContact O-C 3.6Å; D133-T527 VanDerWaalsContact O-CA 3.29Å; D133-T527 WeakPolarHBondContact O-CA 3.41Å; D133-L528 PolarHBondContact O-N 3.15Å
134T98.8Very high96.9Very high1 Ų121.1 Ų21.11%0.00611%0.111CC..SBendtrans-144.1174.7-176.569.80000112.4E136 D137 M138 L485 I488 T527T134-E136 PolarHBondContact O-N 2.92Å; T134-E136 PolarHBondContact OG1-N 3.19Å; T134-D137 PolarHBondContact N-OD2 2.81Å; T134-D137 PolarHBondContact O-N 3.36Å; T134-D137 PolarHBondContact OG1-OD2 3.26Å; T134-D137 VanDerWaalsContact OG1-OD2 3.12Å; T134-M138 PolarHBondContact O-N 2.85Å; T134-L485 HydrophobicContact CG2-CD2 4.24Å; T134-I488 HydrophobicContact CG2-CG2 4.33Å; T134-T527 HydrophobicContact CG2-CG2 4.08Å
135V98.7Very high97Very high0 Ų021.2 Ų21.20%011%0.112CC..Hα-helixtrans-59.4-25.8169.367.10000113.2M138 K139 F166 V169 R525V135-M138 PolarHBondContact O-N 2.85Å; V135-K139 HydrophobicContact CG2-CD 4.31Å; V135-K139 HydrophobicContact CG2-CG 4.48Å; V135-K139 VanDerWaalsContact O-CG 3.3Å; V135-K139 WeakPolarHBondContact O-CG 3.31Å; V135-K139 PolarHBondContact O-N 2.99Å; V135-F166 HydrophobicContact CB-CB 4.49Å; V135-F166 HydrophobicContact CB-CD1 3.93Å; V135-F166 HydrophobicContact CB-CG 4.4Å; V135-V169 HydrophobicContact CG2-CB 3.8Å; V135-V169 HydrophobicContact CG2-CG1 3.7Å; V135-R525 HydrophobicContact CG1-CG 4.08Å
136E98.6Very high97Very high39 Ų3923.9 Ų23.918%0.18213%0.129CC..Hα-helixtrans-68.5-36.1179.8-59.9-55.7145.800112T134 M138 K139 V140 I488 R525T134-E136 PolarHBondContact O-N 2.92Å; T134-E136 PolarHBondContact OG1-N 3.19Å; E136-M138 VanDerWaalsContact C-N 3.33Å; E136-K139 WeakPolarHBondContact O-CB 3.47Å; E136-K139 PolarHBondContact O-N 3.43Å; E136-K139 IonicContact OE1-NZ 2.83Å; E136-K139 PolarHBondContact OE1-NZ 2.97Å; E136-K139 WeakPolarHBondContact OE2-CE 3.4Å; E136-K139 IonicContact OE2-NZ 3.91Å; E136-K139 PolarHBondContact OE2-NZ 2.85Å; E136-V140 WeakPolarHBondContact O-CG2 3.45Å; E136-V140 PolarHBondContact O-N 2.82Å; E136-I488 HydrophobicContact CB-CD1 4.5Å; E136-I488 HydrophobicContact CG-CD1 3.64Å; E136-I488 HydrophobicContact CG-CG1 4.44Å; E136-R525 IonicContact OE1-CZ 3.87Å; E136-R525 VanDerWaalsContact OE1-CZ 3.28Å; E136-R525 IonicContact OE1-NE 3.02Å; E136-R525 PolarHBondContact OE1-NE 3.25Å; E136-R525 IonicContact OE1-NH2 3.34Å; E136-R525 PolarHBondContact OE1-NH2 2.98Å
137D98.5Very high97.1Very high11 Ų1123.9 Ų23.96%0.05913%0.129CC..Hα-helixtrans-67.5-39.8175.8-48.2-55.5000110.4A84 I132 D133 T134 K139 V140 L141 Q481A84-D137 WeakPolarHBondContact CB-O 3.43Å; I132-D137 HydrophobicContact CD1-CB 3.69Å; I132-D137 HydrophobicContact CG2-CB 4.42Å; D133-D137 PolarHBondContact N-OD2 2.84Å; T134-D137 PolarHBondContact N-OD2 2.81Å; T134-D137 PolarHBondContact O-N 3.36Å; T134-D137 PolarHBondContact OG1-OD2 3.26Å; T134-D137 VanDerWaalsContact OG1-OD2 3.12Å; D137-K139 VanDerWaalsContact C-N 3.32Å; D137-K139 PolarHBondContact O-N 3.26Å; D137-V140 PolarHBondContact O-N 3.3Å; D137-L141 WeakPolarHBondContact O-CB 3.43Å; D137-L141 PolarHBondContact O-N 2.82Å; D137-Q481 PolarHBondContact OD1-OE1 2.62Å
138M98.4Very high97.3Very high0 Ų026.3 Ų26.30%014%0.143CC..Hα-helixtrans-63.8-36.5175.2-164.864.576.300112.4F106 I132 T134 V135 E136 L141 F142 V163 F166 A170F106-M138 HydrophobicContact CE1-CE 4.21Å; I132-M138 HydrophobicContact CG2-CE 4.11Å; T134-M138 PolarHBondContact O-N 2.85Å; V135-M138 PolarHBondContact O-N 2.85Å; E136-M138 VanDerWaalsContact C-N 3.33Å; M138-L141 WeakPolarHBondContact O-CB 3.44Å; M138-L141 PolarHBondContact O-N 3.23Å; M138-L141 HydrophobicContact SD-CD2 3.98Å; M138-F142 HydrophobicContact CG-CD2 4.08Å; M138-F142 HydrophobicContact CG-CE2 4.03Å; M138-F142 WeakPolarHBondContact O-CD2 3.5Å; M138-F142 PolarHBondContact O-N 3.1Å; M138-F142 HydrophobicContact SD-CD2 3.97Å; M138-F142 HydrophobicContact SD-CE2 3.39Å; M138-F142 WeakPolarHBondContact SD-CE2 3.36Å; M138-F142 HydrophobicContact SD-CZ 4.3Å; M138-V163 HydrophobicContact CE-CG1 4.12Å; M138-F166 HydrophobicContact CB-CB 3.95Å; M138-F166 HydrophobicContact CE-CB 4.02Å; M138-F166 HydrophobicContact CG-CB 4.12Å; M138-A170 HydrophobicContact CB-CB 4.27Å; M138-A170 HydrophobicContact CG-CB 3.91Å
139K98.5Very high97.5Very high62 Ų6231.9 Ų31.927%0.2716%0.16SC..Hα-helixtrans-65.8-42.8174.1-73.2162.961.1179.40111.8V135 E136 D137 L141 F142 D143 A170 E173V135-K139 HydrophobicContact CG2-CD 4.31Å; V135-K139 HydrophobicContact CG2-CG 4.48Å; V135-K139 VanDerWaalsContact O-CG 3.3Å; V135-K139 WeakPolarHBondContact O-CG 3.31Å; V135-K139 PolarHBondContact O-N 2.99Å; E136-K139 WeakPolarHBondContact O-CB 3.47Å; E136-K139 PolarHBondContact O-N 3.43Å; E136-K139 IonicContact OE1-NZ 2.83Å; E136-K139 PolarHBondContact OE1-NZ 2.97Å; E136-K139 WeakPolarHBondContact OE2-CE 3.4Å; E136-K139 IonicContact OE2-NZ 3.91Å; E136-K139 PolarHBondContact OE2-NZ 2.85Å; D137-K139 VanDerWaalsContact C-N 3.32Å; D137-K139 PolarHBondContact O-N 3.26Å; K139-L141 VanDerWaalsContact C-N 3.33Å; K139-F142 CarbonylContact O-C 3.58Å; K139-F142 PolarHBondContact O-N 2.91Å; K139-D143 PolarHBondContact O-N 3.43Å; K139-A170 HydrophobicContact CG-CB 3.94Å; K139-E173 WeakPolarHBondContact CD-OE2 3.2Å; K139-E173 WeakPolarHBondContact CE-OE2 3.35Å; K139-E173 IonicContact NZ-OE2 3.31Å; K139-E173 PolarHBondContact NZ-OE2 2.79Å
140V98.1Very high97.4Very high64 Ų6433 Ų3339%0.38817%0.166SC..Hα-helixtrans-62.8-42.9174.4173.60000110.5A84 K85 E136 D137 F142 D143A84-V140 HydrophobicContact CB-CB 4.11Å; A84-V140 HydrophobicContact CB-CG1 3.93Å; K85-V140 HydrophobicContact CB-CG1 4.12Å; E136-V140 WeakPolarHBondContact O-CG2 3.45Å; E136-V140 PolarHBondContact O-N 2.82Å; D137-V140 PolarHBondContact O-N 3.3Å; V140-F142 PolarHBondContact O-N 2.82Å; V140-D143 WeakPolarHBondContact O-CB 3.41Å; V140-D143 PolarHBondContact O-N 3.07Å; V140-D143 VanDerWaalsContact O-N 3.15Å
141L98Very high97.4Very high0 Ų034.7 Ų34.70%018%0.177CC..Hα-helixtrans-57.7-37.6179.5-171.864.3000112.3A84 N88 Y91 V104 V130 I132 D137 M138 K139A84-L141 HydrophobicContact CB-CB 4.14Å; A84-L141 HydrophobicContact CB-CD1 4.42Å; N88-L141 WeakPolarHBondContact CB-O 3.46Å; N88-L141 PolarHBondContact ND2-O 2.98Å; Y91-L141 HydrophobicContact CD2-CD1 4.3Å; Y91-L141 HydrophobicContact CE2-CD1 3.54Å; Y91-L141 HydrophobicContact CE2-CG 4.02Å; V104-L141 HydrophobicContact CG1-CD2 3.84Å; V104-L141 HydrophobicContact CG2-CD2 4.3Å; V130-L141 HydrophobicContact CG1-CD1 4.45Å; V130-L141 HydrophobicContact CG1-CD2 4.29Å; V130-L141 HydrophobicContact CG2-CD1 4.26Å; I132-L141 HydrophobicContact CD1-CD2 4.33Å; D137-L141 WeakPolarHBondContact O-CB 3.43Å; D137-L141 PolarHBondContact O-N 2.82Å; M138-L141 WeakPolarHBondContact O-CB 3.44Å; M138-L141 PolarHBondContact O-N 3.23Å; M138-L141 HydrophobicContact SD-CD2 3.98Å; K139-L141 VanDerWaalsContact C-N 3.33Å
142F98.1Very high97.3Very high0 Ų034.7 Ų34.70%018%0.177CC..THydrogen-bonded Turntrans-105.117.2179.2-60.8-57.1000114.4L102 V104 M138 K139 V140 Q144 I145 L147 V152 Y167 Q174L102-F142 HydrophobicContact CD1-CE1 4.41Å; V104-F142 HydrophobicContact CG2-CE1 4.33Å; V104-F142 HydrophobicContact CG2-CZ 4.02Å; M138-F142 HydrophobicContact CG-CD2 4.08Å; M138-F142 HydrophobicContact CG-CE2 4.03Å; M138-F142 WeakPolarHBondContact O-CD2 3.5Å; M138-F142 PolarHBondContact O-N 3.1Å; M138-F142 HydrophobicContact SD-CD2 3.97Å; M138-F142 HydrophobicContact SD-CE2 3.39Å; M138-F142 WeakPolarHBondContact SD-CE2 3.36Å; M138-F142 HydrophobicContact SD-CZ 4.3Å; K139-F142 CarbonylContact O-C 3.58Å; K139-F142 PolarHBondContact O-N 2.91Å; V140-F142 PolarHBondContact O-N 2.82Å; F142-Q144 PolarHBondContact O-N 3.31Å; F142-I145 HydrophobicContact CB-CB 4.5Å; F142-I145 HydrophobicContact CD1-CD1 4.48Å; F142-I145 HydrophobicContact CD1-CG2 4.43Å; F142-I145 PolarHBondContact O-N 3.03Å; F142-L147 HydrophobicContact CB-CD1 4.28Å; F142-L147 HydrophobicContact CB-CD2 4.2Å; F142-L147 HydrophobicContact CB-CG 4.38Å; F142-L147 HydrophobicContact CD1-CD2 3.92Å; F142-L147 HydrophobicContact CD2-CD1 4.2Å; F142-L147 HydrophobicContact CD2-CD2 4.26Å; F142-L147 HydrophobicContact CE1-CD2 4.38Å; F142-L147 HydrophobicContact CG-CD1 4.32Å; F142-L147 HydrophobicContact CG-CD2 3.87Å; F142-L147 HydrophobicContact CG-CG 4.47Å; F142-V152 HydrophobicContact CE1-CG1 3.97Å; F142-V152 HydrophobicContact CE1-CG2 4.22Å; F142-V152 HydrophobicContact CZ-CG1 3.7Å; F142-Y167 HydrophobicContact CD2-CD2 4.41Å; F142-Y167 AromaticContact CE2-CD2 3.75Å; F142-Y167 HydrophobicContact CE2-CD2 3.75Å; F142-Y167 HydrophobicContact CE2-CE2 4.2Å; F142-Y167 HydrophobicContact CZ-CD2 4.34Å; F142-Y167 HydrophobicContact CZ-CE2 4.49Å; F142-Q174 PolarHBondContact O-NE2 2.81Å
143D97.9Very high97.2Very high80 Ų8035.3 Ų35.343%0.42818%0.182SC..THydrogen-bonded Turntrans-56.9131.4175-178.748000110.2N88 K139 V140 I145N88-D143 PolarHBondContact ND2-N 3.13Å; N88-D143 PolarHBondContact ND2-O 3.04Å; K139-D143 PolarHBondContact O-N 3.43Å; V140-D143 WeakPolarHBondContact O-CB 3.41Å; V140-D143 PolarHBondContact O-N 3.07Å; V140-D143 VanDerWaalsContact O-N 3.15Å; D143-I145 PolarHBondContact O-N 3.4Å; D143-I145 VanDerWaalsContact O-N 3.08Å
144Q96.6Very high97.2Very high123 Ų12335.3 Ų35.358%0.57518%0.182SC*.THydrogen-bonded Turntrans53.725.1-176.6-60166.258.700114.8R92 F142R92-Q144 PolarHBondContact NH1-O 3.15Å; F142-Q144 PolarHBondContact O-N 3.31Å
145I96.4Very high97.1Very high5 Ų536 Ų363%0.02619%0.186CC..  trans-114.1107.2171.5-63.4176.5000107.5Y91 R92 L102 F142 D143 L147 M150 Q174Y91-I145 HydrophobicContact CD2-CD1 4.43Å; R92-I145 HydrophobicContact CG-CD1 4.38Å; R92-I145 HydrophobicContact CG-CG1 4.33Å; L102-I145 HydrophobicContact CD1-CD1 4Å; L102-I145 HydrophobicContact CD1-CG2 3.78Å; F142-I145 HydrophobicContact CB-CB 4.5Å; F142-I145 HydrophobicContact CD1-CD1 4.48Å; F142-I145 HydrophobicContact CD1-CG2 4.43Å; F142-I145 PolarHBondContact O-N 3.03Å; D143-I145 PolarHBondContact O-N 3.4Å; D143-I145 VanDerWaalsContact O-N 3.08Å; I145-L147 PolarHBondContact O-N 3.22Å; I145-L147 VanDerWaalsContact O-N 3.09Å; I145-M150 HydrophobicContact CG2-CB 4.3Å; I145-M150 HydrophobicContact CG2-CG 3.76Å; I145-Q174 PolarHBondContact O-NE2 3.4Å; I145-Q174 PolarHBondContact O-OE1 3.22Å
146P96.4Very high97.1Very high56 Ų5636 Ų3636%0.36419%0.186SC..  trans-72.5104.2-17427.9-33.7000111.6D148 K149 M150P146-D148 WeakPolarHBondContact CB-OD1 3.3Å; P146-D148 PolarHBondContact O-N 3.21Å; P146-K149 HydrophobicContact CB-CB 4.44Å; P146-K149 HydrophobicContact CB-CD 4.35Å; P146-K149 HydrophobicContact CG-CB 4.24Å; P146-K149 HydrophobicContact CG-CD 4.27Å; P146-K149 PolarHBondContact O-N 3.08Å; P146-M150 WeakPolarHBondContact O-CG 3.3Å; P146-M150 PolarHBondContact O-N 3.44Å; P146-M150 VanDerWaalsContact O-N 3.11Å
147L97.3Very high97.1Very high0 Ų034.3 Ų34.30%018%0.178CC..THydrogen-bonded Turntrans-67.5-15.6-173.9-68-179.2000114.5F142 I145 K149 V152 Y167 A171 L181F142-L147 HydrophobicContact CB-CD1 4.28Å; F142-L147 HydrophobicContact CB-CD2 4.2Å; F142-L147 HydrophobicContact CB-CG 4.38Å; F142-L147 HydrophobicContact CD1-CD2 3.92Å; F142-L147 HydrophobicContact CD2-CD1 4.2Å; F142-L147 HydrophobicContact CD2-CD2 4.26Å; F142-L147 HydrophobicContact CE1-CD2 4.38Å; F142-L147 HydrophobicContact CG-CD1 4.32Å; F142-L147 HydrophobicContact CG-CD2 3.87Å; F142-L147 HydrophobicContact CG-CG 4.47Å; I145-L147 PolarHBondContact O-N 3.22Å; I145-L147 VanDerWaalsContact O-N 3.09Å; L147-K149 VanDerWaalsContact C-N 3.3Å; L147-V152 HydrophobicContact CD2-CG2 3.89Å; L147-Y167 HydrophobicContact CD1-CD2 4.43Å; L147-Y167 HydrophobicContact CD1-CE2 4.02Å; L147-Y167 HydrophobicContact CD2-CE2 3.93Å; L147-A171 HydrophobicContact CB-CB 4.49Å; L147-A171 HydrophobicContact CD1-CB 3.83Å; L147-L181 HydrophobicContact CB-CD2 3.96Å
148D96.6Very high97Very high71 Ų7134 Ų3438%0.3818%0.178SC..THydrogen-bonded Turntrans-77.1-14.8171.867.6-46.8000113.6P146 V176P146-D148 WeakPolarHBondContact CB-OD1 3.3Å; P146-D148 PolarHBondContact O-N 3.21Å; D148-V176 HydrophobicContact CB-CG1 3.86Å; D148-V176 HydrophobicContact CB-CG2 3.92Å
149K94.6Very high97Very high156 Ų15634.1 Ų34.168%0.67818%0.178SC*.THydrogen-bonded Turntrans-116.3-15.9-177.8-63.3176.1-172.5174.20113.4P146 L147P146-K149 HydrophobicContact CB-CB 4.44Å; P146-K149 HydrophobicContact CB-CD 4.35Å; P146-K149 HydrophobicContact CG-CB 4.24Å; P146-K149 HydrophobicContact CG-CD 4.27Å; P146-K149 PolarHBondContact O-N 3.08Å; L147-K149 VanDerWaalsContact C-N 3.3Å
150M93.4Very high97.1Very high25 Ų2531.3 Ų31.312%0.12317%0.166CC..  trans-101.2135.6-177.6-68.7-53.4-55.100111.5L95 L102 I145 P146 V152 T182L95-M150 HydrophobicContact CD1-CE 4.04Å; L95-M150 HydrophobicContact CD2-CE 3.44Å; L95-M150 VanDerWaalsContact CD2-CE 3.44Å; L95-M150 HydrophobicContact CG-CE 4.41Å; L102-M150 HydrophobicContact CD1-CE 4.48Å; L102-M150 HydrophobicContact CG-CE 4.11Å; I145-M150 HydrophobicContact CG2-CB 4.3Å; I145-M150 HydrophobicContact CG2-CG 3.76Å; P146-M150 WeakPolarHBondContact O-CG 3.3Å; P146-M150 PolarHBondContact O-N 3.44Å; P146-M150 VanDerWaalsContact O-N 3.11Å; M150-V152 HydrophobicContact CB-CG2 4.43Å; M150-T182 PolarHBondContact O-OG1 3.23Å
151S94.7Very high97.1Very high34 Ų3428.4 Ų28.424%0.23815%0.149CC..EExtended strand (participates in β ladder)trans-88.6119.4165.6-173.30000109.7R76 L102 T182R76-S151 PolarHBondContact NH2-OG 2.94Å; L102-S151 PolarHBondContact N-O 3.06Å; S151-T182 WeakPolarHBondContact CA-O 3.43Å; S151-T182 WeakPolarHBondContact CA-OG1 3.48Å
152V96.3Very high97.1Very high0 Ų028.4 Ų28.40%015%0.149CC..EExtended strand (participates in β ladder)trans-112.1118.3-176.8-176.40000110.6V104 F142 L147 M150 M154 Y167 T182 G183 T184V104-V152 HydrophobicContact CG2-CG1 4.14Å; F142-V152 HydrophobicContact CE1-CG1 3.97Å; F142-V152 HydrophobicContact CE1-CG2 4.22Å; F142-V152 HydrophobicContact CZ-CG1 3.7Å; L147-V152 HydrophobicContact CD2-CG2 3.89Å; M150-V152 HydrophobicContact CB-CG2 4.43Å; V152-M154 HydrophobicContact CG1-CG 4.09Å; V152-Y167 HydrophobicContact CB-CE2 4.2Å; V152-Y167 HydrophobicContact CG1-CE2 4.36Å; V152-Y167 HydrophobicContact CG2-CE2 4.26Å; V152-T182 PolarHBondContact N-O 2.92Å; V152-T182 VanDerWaalsContact N-O 3.09Å; V152-G183 CarbonylContact O-C 3.38Å; V152-G183 WeakPolarHBondContact O-CA 3.45Å; V152-T184 PolarHBondContact O-N 2.95Å
153S96.7Very high97.2Very high14 Ų1428.4 Ų28.410%0.09815%0.149CC..EExtended strand (participates in β ladder)trans-85.6139.9163.1-120.40000109.8R76 L102 S103 V104 T184R76-S153 PolarHBondContact NH1-OG 3.42Å; L102-S153 PolarHBondContact O-N 3.06Å; S103-S153 CarbonylContact C-O 3.48Å; S103-S153 VanDerWaalsContact CA-O 3.31Å; S103-S153 WeakPolarHBondContact CA-O 3.35Å; S103-S153 VanDerWaalsContact OG-CB 3.22Å; S103-S153 WeakPolarHBondContact OG-CB 3.44Å; V104-S153 PolarHBondContact N-O 2.96Å; S153-T184 CarbonylContact C-O 3.47Å; S153-T184 VanDerWaalsContact CA-O 3.28Å; S153-T184 WeakPolarHBondContact CA-O 3.47Å
154M97.9Very high97.2Very high1 Ų124.6 Ų24.61%0.00513%0.129CC..EExtended strand (participates in β ladder)trans-128.2115.2171.4-69.4-179.2-71.900108.2V104 F106 V152 M156 V163 L164 Y167 T184 I185 Q186 F224V104-M154 HydrophobicContact CB-CG 4.4Å; V104-M154 HydrophobicContact CG2-CG 4.42Å; F106-M154 HydrophobicContact CE2-CB 3.91Å; F106-M154 HydrophobicContact CE2-CG 4.3Å; F106-M154 HydrophobicContact CZ-CB 4.15Å; F106-M154 HydrophobicContact CZ-CG 4.06Å; F106-M154 HydrophobicContact CZ-SD 4.32Å; V152-M154 HydrophobicContact CG1-CG 4.09Å; M154-M156 PolarHBondContact O-N 2.92Å; M154-M156 VanDerWaalsContact O-N 3.15Å; M154-V163 HydrophobicContact SD-CG1 4.25Å; M154-L164 HydrophobicContact CE-CD1 4.08Å; M154-Y167 HydrophobicContact CE-CD1 3.5Å; M154-Y167 VanDerWaalsContact CE-CD1 3.5Å; M154-Y167 HydrophobicContact CE-CD2 4.11Å; M154-Y167 HydrophobicContact CE-CE1 4.07Å; M154-Y167 HydrophobicContact CE-CG 3.51Å; M154-Y167 HydrophobicContact SD-CD2 4.18Å; M154-Y167 HydrophobicContact SD-CG 3.93Å; M154-T184 PolarHBondContact N-O 3.19Å; M154-I185 HydrophobicContact CB-CD1 3.67Å; M154-I185 HydrophobicContact CE-CD1 4.28Å; M154-Q186 PolarHBondContact O-N 3.36Å; M154-F224 HydrophobicContact CE-CE2 4.47Å; M154-F224 HydrophobicContact CE-CZ 3.89Å
155T97Very high97.3Very high15 Ų1518.8 Ų18.89%0.09210%0.101CC..  trans-85.987175.9-63.20000108.2Y78 V104 F106 H111Y78-T155 VanDerWaalsContact CE2-CB 3.41Å; Y78-T155 HydrophobicContact CE2-CG2 4.22Å; Y78-T155 WeakPolarHBondContact CE2-OG1 3.38Å; Y78-T155 WeakPolarHBondContact OH-CB 3.18Å; Y78-T155 VanDerWaalsContact OH-CG2 3.31Å; Y78-T155 WeakPolarHBondContact OH-CG2 3.05Å; V104-T155 PolarHBondContact O-N 3.15Å; F106-T155 WeakPolarHBondContact CD2-O 3.46Å; H111-T155 PolarHBondContact CE1-O 3.13Å; H111-T155 PolarHBondContact NE2-O 2.97Å
156M98.4Very high97.4Very high0 Ų018.5 Ų18.50%010%0.1CC..  trans-143.9139.4-179.5-178.856.656.900110F106 T110 H111 M154 A159 V163 I185 N187F106-M156 HydrophobicContact CB-CE 3.49Å; F106-M156 VanDerWaalsContact CB-CE 3.49Å; F106-M156 HydrophobicContact CD1-CE 4.32Å; F106-M156 HydrophobicContact CD2-CB 4.16Å; F106-M156 HydrophobicContact CD2-CE 3.42Å; F106-M156 VanDerWaalsContact CD2-CE 3.42Å; F106-M156 HydrophobicContact CE2-CB 4.03Å; F106-M156 HydrophobicContact CE2-CE 4.19Å; F106-M156 HydrophobicContact CG-CE 3.48Å; F106-M156 VanDerWaalsContact CG-CE 3.48Å; T110-M156 HydrophobicContact CG2-CE 3.81Å; H111-M156 HydrophobicContact CB-CE 4.33Å; H111-M156 HydrophobicContact CB-SD 4.47Å; M154-M156 PolarHBondContact O-N 2.92Å; M154-M156 VanDerWaalsContact O-N 3.15Å; M156-A159 HydrophobicContact SD-CB 4.05Å; M156-V163 HydrophobicContact CB-CG1 4.18Å; M156-V163 HydrophobicContact CE-CG2 4.09Å; M156-V163 HydrophobicContact CG-CB 3.86Å; M156-V163 HydrophobicContact CG-CG1 4.06Å; M156-V163 HydrophobicContact CG-CG2 3.84Å; M156-V163 HydrophobicContact SD-CG2 4.27Å; M156-I185 HydrophobicContact CB-CD1 3.91Å; M156-N187 PolarHBondContact O-N 3.36Å
157N98.6Very high97.6Very high4 Ų415.9 Ų15.92%0.0218%0.083CC..SBendtrans-137.3-60.9-174.1-47.5-80.7000111.9V160 Q186 N187 D188 K191 E192N157-V160 VanDerWaalsContact O-CB 3.25Å; N157-V160 WeakPolarHBondContact O-CB 3.37Å; N157-V160 VanDerWaalsContact O-CG1 3.24Å; N157-V160 WeakPolarHBondContact O-CG1 3.4Å; N157-V160 PolarHBondContact O-N 3.33Å; N157-Q186 PolarHBondContact ND2-OE1 3.41Å; N157-Q186 WeakPolarHBondContact OD1-CB 3.44Å; N157-Q186 VanDerWaalsContact OD1-CG 3.26Å; N157-Q186 WeakPolarHBondContact OD1-CG 3.22Å; N157-Q186 PolarHBondContact OD1-OE1 3.31Å; N157-Q186 VanDerWaalsContact OD1-OE1 3.09Å; N157-N187 PolarHBondContact OD1-N 2.98Å; N157-D188 PolarHBondContact OD1-N 3.1Å; N157-D188 PolarHBondContact OD1-O 3.32Å; N157-K191 PolarHBondContact ND2-NZ 3.2Å; N157-K191 PolarHBondContact OD1-NZ 3.44Å; N157-E192 HydrophobicContact CB-CG 3.81Å; N157-E192 WeakPolarHBondContact CB-OE1 3.41Å; N157-E192 PolarHBondContact ND2-OE1 3.04Å
158G98Very high97.6Very high5 Ų515.9 Ų15.95%0.0528%0.083CC..THydrogen-bonded Turntrans-58.5-65.5179.600000112.5V160 T198G158-V160 PolarHBondContact O-N 3.21Å; G158-V160 VanDerWaalsContact O-N 3.12Å; G158-T198 VanDerWaalsContact CA-O 3.26Å; G158-T198 WeakPolarHBondContact CA-O 3.46Å
159A98.7Very high97.7Very high1 Ų112.5 Ų12.51%0.0087%0.065CC..THydrogen-bonded Turntrans-84.637.6176.900000113.2T110 H111 M156 L161 P162 V163 I200 L528T110-A159 WeakPolarHBondContact O-CB 3.29Å; H111-A159 PolarHBondContact O-N 3.37Å; H111-A159 VanDerWaalsContact O-N 3.09Å; M156-A159 HydrophobicContact SD-CB 4.05Å; A159-L161 VanDerWaalsContact C-N 3.31Å; A159-L161 PolarHBondContact O-N 3.25Å; A159-P162 HydrophobicContact CB-CG 3.96Å; A159-P162 VanDerWaalsContact O-CD 3.27Å; A159-P162 WeakPolarHBondContact O-CD 3.19Å; A159-P162 WeakPolarHBondContact O-CG 3.24Å; A159-V163 WeakPolarHBondContact O-CG2 3.15Å; A159-V163 PolarHBondContact O-N 2.86Å; A159-I200 HydrophobicContact CB-CD1 4.06Å; A159-L528 HydrophobicContact CB-CD1 4.3Å; A159-L528 HydrophobicContact CB-CD2 4.41Å; A159-L528 HydrophobicContact CB-CG 4.47Å
160V98.8Very high97.9Very high3 Ų35.1 Ų5.12%0.0183%0.033CC..Hα-helixtrans-61.7-36.6-173.763.20000113.4N157 G158 L164 I185 N187 I209 I213N157-V160 VanDerWaalsContact O-CB 3.25Å; N157-V160 WeakPolarHBondContact O-CB 3.37Å; N157-V160 VanDerWaalsContact O-CG1 3.24Å; N157-V160 WeakPolarHBondContact O-CG1 3.4Å; N157-V160 PolarHBondContact O-N 3.33Å; G158-V160 PolarHBondContact O-N 3.21Å; G158-V160 VanDerWaalsContact O-N 3.12Å; V160-L164 WeakPolarHBondContact O-CB 3.32Å; V160-L164 PolarHBondContact O-N 2.87Å; V160-I185 HydrophobicContact CG2-CD1 4.07Å; V160-I185 HydrophobicContact CG2-CG1 3.53Å; V160-N187 HydrophobicContact CG2-CB 4.04Å; V160-I209 HydrophobicContact CG1-CG2 3.74Å; V160-I213 HydrophobicContact CB-CD1 4.31Å; V160-I213 HydrophobicContact CG1-CD1 3.64Å; V160-I213 HydrophobicContact CG2-CD1 3.73Å
161L98.9Very high98.2Very high3 Ų34 Ų42%0.0163%0.027CC..Hα-helixtrans-63.8-57.6-179.7-74.9170.1000113.1A159 V163 A165 I209 I213 L514 L515 A518 L535A159-L161 VanDerWaalsContact C-N 3.31Å; A159-L161 PolarHBondContact O-N 3.25Å; L161-V163 PolarHBondContact O-N 3.48Å; L161-A165 WeakPolarHBondContact O-CB 3.33Å; L161-A165 PolarHBondContact O-N 3.19Å; L161-I209 HydrophobicContact CD1-CB 4.45Å; L161-I209 HydrophobicContact CD1-CD1 4.08Å; L161-I209 HydrophobicContact CD1-CG1 3.93Å; L161-I209 HydrophobicContact CD1-CG2 3.76Å; L161-I209 HydrophobicContact CD2-CG2 4.17Å; L161-I209 HydrophobicContact CG-CG2 3.69Å; L161-I213 HydrophobicContact CD2-CD1 4.18Å; L161-I213 HydrophobicContact CD2-CG1 4.06Å; L161-L514 HydrophobicContact CD1-CB 3.83Å; L161-L514 HydrophobicContact CD1-CD1 4.37Å; L161-L514 HydrophobicContact CD2-CB 4.13Å; L161-L515 HydrophobicContact CD2-CB 3.92Å; L161-L515 HydrophobicContact CD2-CD1 4.14Å; L161-A518 HydrophobicContact CB-CB 4.12Å; L161-L535 HydrophobicContact CD1-CD1 3.51Å; L161-L535 HydrophobicContact CD1-CD2 4.43Å
162P98.8Very high98.3Very high1 Ų15.2 Ų5.21%0.0063%0.029CC..Hα-helixtrans-60.9-42.6178.419.8-30.4000112.3A159 A165 F166 L528 I531A159-P162 HydrophobicContact CB-CG 3.96Å; A159-P162 VanDerWaalsContact O-CD 3.27Å; A159-P162 WeakPolarHBondContact O-CD 3.19Å; A159-P162 WeakPolarHBondContact O-CG 3.24Å; P162-A165 WeakPolarHBondContact O-CB 3.02Å; P162-A165 PolarHBondContact O-N 3.47Å; P162-F166 HydrophobicContact CB-CE2 4.22Å; P162-F166 HydrophobicContact CB-CZ 4.21Å; P162-F166 WeakPolarHBondContact O-CD1 3.2Å; P162-F166 WeakPolarHBondContact O-CD2 3.33Å; P162-F166 WeakPolarHBondContact O-CG 3.39Å; P162-F166 PolarHBondContact O-N 2.73Å; P162-L528 HydrophobicContact CB-CB 4.46Å; P162-L528 HydrophobicContact CB-CD1 4.23Å; P162-L528 HydrophobicContact CB-CG 4.1Å; P162-L528 HydrophobicContact CG-CD1 4.15Å; P162-L528 HydrophobicContact CG-CG 3.96Å; P162-I531 HydrophobicContact CB-CB 4.05Å; P162-I531 HydrophobicContact CB-CD1 3.99Å; P162-I531 HydrophobicContact CB-CG2 3.81Å; P162-I531 HydrophobicContact CG-CG2 4.08Å
163V98.8Very high98.4Very high0 Ų09.2 Ų9.20%05%0.048CC..Hα-helixtrans-64.9-45.4-178.31720000112F106 T110 M138 M154 M156 A159 L161 A165 F166 Y167 L528F106-V163 HydrophobicContact CE1-CG1 3.94Å; F106-V163 HydrophobicContact CE2-CG1 4.05Å; F106-V163 HydrophobicContact CZ-CG1 3.52Å; T110-V163 HydrophobicContact CG2-CG2 3.94Å; M138-V163 HydrophobicContact CE-CG1 4.12Å; M154-V163 HydrophobicContact SD-CG1 4.25Å; M156-V163 HydrophobicContact CB-CG1 4.18Å; M156-V163 HydrophobicContact CE-CG2 4.09Å; M156-V163 HydrophobicContact CG-CB 3.86Å; M156-V163 HydrophobicContact CG-CG1 4.06Å; M156-V163 HydrophobicContact CG-CG2 3.84Å; M156-V163 HydrophobicContact SD-CG2 4.27Å; A159-V163 WeakPolarHBondContact O-CG2 3.15Å; A159-V163 PolarHBondContact O-N 2.86Å; L161-V163 PolarHBondContact O-N 3.48Å; V163-A165 VanDerWaalsContact C-N 3.33Å; V163-F166 PolarHBondContact O-N 2.84Å; V163-Y167 PolarHBondContact O-N 3.08Å; V163-L528 HydrophobicContact CG2-CD1 3.75Å
164L98.8Very high98.5Very high0 Ų012 Ų120%06%0.059CC..Hα-helixtrans-66.7-37.6176.6-17757.9000111.3M154 V160 Y167 I168 I213 F224 L515M154-L164 HydrophobicContact CE-CD1 4.08Å; V160-L164 WeakPolarHBondContact O-CB 3.32Å; V160-L164 PolarHBondContact O-N 2.87Å; L164-Y167 HydrophobicContact CD1-CD1 4.17Å; L164-Y167 PolarHBondContact O-N 2.91Å; L164-I168 HydrophobicContact CD1-CD1 4.37Å; L164-I168 HydrophobicContact CG-CD1 4.06Å; L164-I168 WeakPolarHBondContact O-CD1 3.37Å; L164-I168 VanDerWaalsContact O-CG1 3.3Å; L164-I168 WeakPolarHBondContact O-CG1 3.42Å; L164-I168 PolarHBondContact O-N 3.37Å; L164-I213 HydrophobicContact CD2-CG1 4.49Å; L164-I213 HydrophobicContact CD2-CG2 3.89Å; L164-F224 HydrophobicContact CD1-CE1 4.08Å; L164-F224 HydrophobicContact CD1-CZ 4.13Å; L164-L515 HydrophobicContact CB-CD1 4.28Å; L164-L515 HydrophobicContact CD2-CD1 3.99Å; L164-L515 HydrophobicContact CD2-CD2 3.71Å; L164-L515 HydrophobicContact CG-CD1 4.08Å; L164-L515 HydrophobicContact CG-CD2 4.4Å
165A98.9Very high98.5Very high0 Ų014.9 Ų14.90%09%0.09CC..Hα-helixtrans-61-46.5174.200000112L161 P162 V163 Y167 I168 V169 A518 V519 A522L161-A165 WeakPolarHBondContact O-CB 3.33Å; L161-A165 PolarHBondContact O-N 3.19Å; P162-A165 WeakPolarHBondContact O-CB 3.02Å; P162-A165 PolarHBondContact O-N 3.47Å; V163-A165 VanDerWaalsContact C-N 3.33Å; A165-Y167 VanDerWaalsContact C-N 3.33Å; A165-Y167 PolarHBondContact O-N 3.43Å; A165-I168 PolarHBondContact O-N 3.31Å; A165-V169 WeakPolarHBondContact O-CG2 3.12Å; A165-V169 PolarHBondContact O-N 3.09Å; A165-A518 HydrophobicContact CB-CB 4.1Å; A165-V519 HydrophobicContact CB-CB 4.47Å; A165-V519 HydrophobicContact CB-CG2 4Å; A165-A522 HydrophobicContact CB-CB 3.85Å
166F98.8Very high98.6Very high0 Ų014.7 Ų14.70%09%0.088CC..Hα-helixtrans-61.9-40175.8-62-23000112.2I132 V135 M138 P162 V163 V169 A170 A522 L528 I531I132-F166 HydrophobicContact CG2-CD2 3.85Å; I132-F166 HydrophobicContact CG2-CE2 4.3Å; V135-F166 HydrophobicContact CB-CB 4.49Å; V135-F166 HydrophobicContact CB-CD1 3.93Å; V135-F166 HydrophobicContact CB-CG 4.4Å; M138-F166 HydrophobicContact CB-CB 3.95Å; M138-F166 HydrophobicContact CE-CB 4.02Å; M138-F166 HydrophobicContact CG-CB 4.12Å; P162-F166 HydrophobicContact CB-CE2 4.22Å; P162-F166 HydrophobicContact CB-CZ 4.21Å; P162-F166 WeakPolarHBondContact O-CD1 3.2Å; P162-F166 WeakPolarHBondContact O-CD2 3.33Å; P162-F166 WeakPolarHBondContact O-CG 3.39Å; P162-F166 PolarHBondContact O-N 2.73Å; V163-F166 PolarHBondContact O-N 2.84Å; F166-V169 PolarHBondContact O-N 3.09Å; F166-A170 WeakPolarHBondContact O-CB 3.27Å; F166-A170 PolarHBondContact O-N 3.38Å; F166-A522 HydrophobicContact CD1-CB 3.53Å; F166-A522 HydrophobicContact CE1-CB 3.78Å; F166-L528 HydrophobicContact CE2-CB 3.94Å; F166-L528 HydrophobicContact CE2-CD1 4.26Å; F166-L528 HydrophobicContact CZ-CB 4.3Å; F166-I531 HydrophobicContact CE1-CD1 3.96Å; F166-I531 HydrophobicContact CZ-CD1 4.14Å
167Y98.7Very high98.6Very high0 Ų017.6 Ų17.60%011%0.106CC..Hα-helixtrans-61.2-45.4174.7173.2-112.3000112.3F142 L147 V152 M154 V163 L164 A165 A171 L181 M221 F224F142-Y167 HydrophobicContact CD2-CD2 4.41Å; F142-Y167 AromaticContact CE2-CD2 3.75Å; F142-Y167 HydrophobicContact CE2-CD2 3.75Å; F142-Y167 HydrophobicContact CE2-CE2 4.2Å; F142-Y167 HydrophobicContact CZ-CD2 4.34Å; F142-Y167 HydrophobicContact CZ-CE2 4.49Å; L147-Y167 HydrophobicContact CD1-CD2 4.43Å; L147-Y167 HydrophobicContact CD1-CE2 4.02Å; L147-Y167 HydrophobicContact CD2-CE2 3.93Å; V152-Y167 HydrophobicContact CB-CE2 4.2Å; V152-Y167 HydrophobicContact CG1-CE2 4.36Å; V152-Y167 HydrophobicContact CG2-CE2 4.26Å; M154-Y167 HydrophobicContact CE-CD1 3.5Å; M154-Y167 VanDerWaalsContact CE-CD1 3.5Å; M154-Y167 HydrophobicContact CE-CD2 4.11Å; M154-Y167 HydrophobicContact CE-CE1 4.07Å; M154-Y167 HydrophobicContact CE-CG 3.51Å; M154-Y167 HydrophobicContact SD-CD2 4.18Å; M154-Y167 HydrophobicContact SD-CG 3.93Å; V163-Y167 PolarHBondContact O-N 3.08Å; L164-Y167 HydrophobicContact CD1-CD1 4.17Å; L164-Y167 PolarHBondContact O-N 2.91Å; A165-Y167 VanDerWaalsContact C-N 3.33Å; A165-Y167 PolarHBondContact O-N 3.43Å; Y167-A171 WeakPolarHBondContact O-CB 3.31Å; Y167-A171 PolarHBondContact O-N 3.35Å; Y167-L181 HydrophobicContact CD1-CD1 4.35Å; Y167-L181 HydrophobicContact CE1-CB 4.27Å; Y167-L181 HydrophobicContact CE1-CD1 3.82Å; Y167-L181 HydrophobicContact CE1-CD2 4.35Å; Y167-L181 HydrophobicContact CE1-CG 4.37Å; Y167-M221 HydrophobicContact CE1-CE 4.19Å; Y167-F224 HydrophobicContact CD1-CE2 4.42Å; Y167-F224 HydrophobicContact CE1-CD2 4.39Å; Y167-F224 AromaticContact CE1-CE2 3.69Å; Y167-F224 HydrophobicContact CE1-CE2 3.69Å; Y167-F224 HydrophobicContact CE1-CZ 4.32Å
168I98.7Very high98.5Very high0 Ų018.5 Ų18.50%011%0.113CC..Hα-helixtrans-61.8-49177.4-69.1162000110.5L164 A165 A171 E172 P178 W216 M221 L515 V519L164-I168 HydrophobicContact CD1-CD1 4.37Å; L164-I168 HydrophobicContact CG-CD1 4.06Å; L164-I168 WeakPolarHBondContact O-CD1 3.37Å; L164-I168 VanDerWaalsContact O-CG1 3.3Å; L164-I168 WeakPolarHBondContact O-CG1 3.42Å; L164-I168 PolarHBondContact O-N 3.37Å; A165-I168 PolarHBondContact O-N 3.31Å; I168-A171 WeakPolarHBondContact O-CB 3.43Å; I168-A171 PolarHBondContact O-N 3.29Å; I168-E172 HydrophobicContact CG2-CG 4.47Å; I168-E172 WeakPolarHBondContact O-CG 3.49Å; I168-E172 PolarHBondContact O-N 3.39Å; I168-P178 HydrophobicContact CG2-CG 4.19Å; I168-W216 HydrophobicContact CD1-CH2 3.92Å; I168-W216 HydrophobicContact CD1-CZ3 3.69Å; I168-W216 HydrophobicContact CG2-CH2 4.47Å; I168-M221 HydrophobicContact CD1-SD 3.92Å; I168-M221 HydrophobicContact CG1-CE 4.49Å; I168-M221 HydrophobicContact CG1-SD 3.97Å; I168-L515 HydrophobicContact CD1-CD1 4.43Å; I168-L515 HydrophobicContact CD1-CD2 4.44Å; I168-V519 HydrophobicContact CB-CG2 4.46Å; I168-V519 HydrophobicContact CD1-CG2 3.85Å; I168-V519 HydrophobicContact CG2-CG1 4.14Å; I168-V519 HydrophobicContact CG2-CG2 4.39Å
169V98.8Very high98.5Very high1 Ų121.6 Ų21.61%0.00613%0.128CC..Hα-helixtrans-68-39-178.4179.90000111.5V135 A165 F166 A171 E172 E173 V519 A522 R523V135-V169 HydrophobicContact CG2-CB 3.8Å; V135-V169 HydrophobicContact CG2-CG1 3.7Å; A165-V169 WeakPolarHBondContact O-CG2 3.12Å; A165-V169 PolarHBondContact O-N 3.09Å; F166-V169 PolarHBondContact O-N 3.09Å; V169-A171 VanDerWaalsContact C-N 3.28Å; V169-A171 PolarHBondContact O-N 2.69Å; V169-E172 PolarHBondContact O-N 2.96Å; V169-E173 HydrophobicContact CG1-CG 4.41Å; V169-E173 WeakPolarHBondContact O-CG 3.37Å; V169-E173 PolarHBondContact O-N 2.98Å; V169-V519 HydrophobicContact CG2-CG1 3.95Å; V169-A522 HydrophobicContact CG2-CB 3.86Å; V169-R523 HydrophobicContact CB-CG 4.46Å; V169-R523 HydrophobicContact CG1-CG 3.95Å; V169-R523 HydrophobicContact CG2-CG 3.56Å
170A98.6Very high98.4Very high1 Ų125.7 Ų25.71%0.00815%0.145CC..Hα-helixtrans-60.4-38.5174.300000111.7M138 K139 F166 Q174M138-A170 HydrophobicContact CB-CB 4.27Å; M138-A170 HydrophobicContact CG-CB 3.91Å; K139-A170 HydrophobicContact CG-CB 3.94Å; F166-A170 WeakPolarHBondContact O-CB 3.27Å; F166-A170 PolarHBondContact O-N 3.38Å; A170-Q174 WeakPolarHBondContact O-CG 3.39Å; A170-Q174 PolarHBondContact O-N 3.41Å; A170-Q174 VanDerWaalsContact O-N 3.15Å
171A98.6Very high98.4Very high0 Ų025.6 Ų25.60%015%0.145CC..Hα-helixtrans-67-44.8172.600000113.2L147 Y167 I168 V169 E173 Q174 G175 V176 L181L147-A171 HydrophobicContact CB-CB 4.49Å; L147-A171 HydrophobicContact CD1-CB 3.83Å; Y167-A171 WeakPolarHBondContact O-CB 3.31Å; Y167-A171 PolarHBondContact O-N 3.35Å; I168-A171 WeakPolarHBondContact O-CB 3.43Å; I168-A171 PolarHBondContact O-N 3.29Å; V169-A171 VanDerWaalsContact C-N 3.28Å; V169-A171 PolarHBondContact O-N 2.69Å; A171-E173 PolarHBondContact O-N 3.39Å; A171-Q174 CarbonylContact O-C 3.45Å; A171-Q174 WeakPolarHBondContact O-CA 3.44Å; A171-Q174 WeakPolarHBondContact O-CB 3.3Å; A171-Q174 PolarHBondContact O-N 2.8Å; A171-G175 PolarHBondContact O-N 2.82Å; A171-V176 CarbonylContact C-O 3.46Å; A171-V176 HydrophobicContact CB-CB 4.26Å; A171-V176 WeakPolarHBondContact O-CB 3.49Å; A171-V176 PolarHBondContact O-N 3.4Å; A171-L181 HydrophobicContact CB-CD1 3.81Å; A171-L181 HydrophobicContact CB-CD2 3.59Å; A171-L181 HydrophobicContact CB-CG 4.23Å
172E98.5Very high98.3Very high61 Ų6127.3 Ų27.329%0.28516%0.155SC..Hα-helixtrans-56.8-41.3175.6-72.817716800110.8I168 V169 Q174 G175 V176 R523I168-E172 HydrophobicContact CG2-CG 4.47Å; I168-E172 WeakPolarHBondContact O-CG 3.49Å; I168-E172 PolarHBondContact O-N 3.39Å; V169-E172 PolarHBondContact O-N 2.96Å; E172-Q174 VanDerWaalsContact C-N 3.31Å; E172-Q174 PolarHBondContact O-N 2.86Å; E172-G175 WeakPolarHBondContact O-CA 3.47Å; E172-G175 PolarHBondContact O-N 3.34Å; E172-V176 WeakPolarHBondContact CA-O 3.34Å; E172-V176 PolarHBondContact N-O 2.73Å; E172-R523 VanDerWaalsContact CD-NH2 3.33Å; E172-R523 IonicContact OE1-CZ 2.7Å; E172-R523 IonicContact OE1-NH2 3.18Å; E172-R523 PolarHBondContact OE1-NH2 3.17Å; E172-R523 IonicContact OE2-CZ 3.82Å; E172-R523 IonicContact OE2-NE 3.94Å; E172-R523 PolarHBondContact OE2-NE 3.36Å; E172-R523 IonicContact OE2-NH2 3.86Å; E172-R523 PolarHBondContact OE2-NH2 3.38Å
173E98.4Very high98.1Very high83 Ų8327.3 Ų27.339%0.38816%0.156SC..Hα-helixtrans-73.1-17.8177.4-69.5-173.2-166.100113.9K139 V169 A171 G175 R525K139-E173 WeakPolarHBondContact CD-OE2 3.2Å; K139-E173 WeakPolarHBondContact CE-OE2 3.35Å; K139-E173 IonicContact NZ-OE2 3.31Å; K139-E173 PolarHBondContact NZ-OE2 2.79Å; V169-E173 HydrophobicContact CG1-CG 4.41Å; V169-E173 WeakPolarHBondContact O-CG 3.37Å; V169-E173 PolarHBondContact O-N 2.98Å; A171-E173 PolarHBondContact O-N 3.39Å; E173-G175 VanDerWaalsContact C-N 3.27Å; E173-R525 VanDerWaalsContact CD-NH2 3.27Å; E173-R525 IonicContact OE1-CZ 2.97Å; E173-R525 IonicContact OE1-NH1 2.89Å; E173-R525 PolarHBondContact OE1-NH1 3.41Å; E173-R525 IonicContact OE1-NH2 3.95Å; E173-R525 PolarHBondContact OE1-NH2 3.42Å; E173-R525 IonicContact OE2-NH2 3.74Å; E173-R525 PolarHBondContact OE2-NH2 2.96Å
174Q98.1Very high98.1Very high72 Ų7227.8 Ų27.834%0.33616%0.159SC..THydrogen-bonded Turntrans-81.1-2.8164-69.5-176.15.400113.1F142 I145 A170 A171 E172 V176F142-Q174 PolarHBondContact O-NE2 2.81Å; I145-Q174 PolarHBondContact O-NE2 3.4Å; I145-Q174 PolarHBondContact O-OE1 3.22Å; A170-Q174 WeakPolarHBondContact O-CG 3.39Å; A170-Q174 PolarHBondContact O-N 3.41Å; A170-Q174 VanDerWaalsContact O-N 3.15Å; A171-Q174 CarbonylContact O-C 3.45Å; A171-Q174 WeakPolarHBondContact O-CA 3.44Å; A171-Q174 WeakPolarHBondContact O-CB 3.3Å; A171-Q174 PolarHBondContact O-N 2.8Å; E172-Q174 VanDerWaalsContact C-N 3.31Å; E172-Q174 PolarHBondContact O-N 2.86Å; Q174-V176 HydrophobicContact CB-CG2 4.23Å
175G98.2Very high98.1Very high63 Ų6327.8 Ų27.865%0.64916%0.159SC*.THydrogen-bonded Turntrans80.419.3-174.100000114A171 E172 E173A171-G175 PolarHBondContact O-N 2.82Å; E172-G175 WeakPolarHBondContact O-CA 3.47Å; E172-G175 PolarHBondContact O-N 3.34Å; E173-G175 VanDerWaalsContact C-N 3.27Å
176V98.4Very high98.1Very high10 Ų1028 Ų286%0.06116%0.16CC..  trans-102.2121.1179.7-177.30000109.8D148 A171 E172 Q174 K180 L181D148-V176 HydrophobicContact CB-CG1 3.86Å; D148-V176 HydrophobicContact CB-CG2 3.92Å; A171-V176 CarbonylContact C-O 3.46Å; A171-V176 HydrophobicContact CB-CB 4.26Å; A171-V176 WeakPolarHBondContact O-CB 3.49Å; A171-V176 PolarHBondContact O-N 3.4Å; E172-V176 WeakPolarHBondContact CA-O 3.34Å; E172-V176 PolarHBondContact N-O 2.73Å; Q174-V176 HydrophobicContact CB-CG2 4.23Å; V176-K180 HydrophobicContact CG1-CB 3.9Å; V176-K180 HydrophobicContact CG1-CD 4.47Å; V176-L181 HydrophobicContact CG1-CD2 3.89Å; V176-L181 HydrophobicContact CG1-CG 4.47Å
177T97.9Very high98Very high62 Ų6228.2 Ų28.238%0.3816%0.161SC..  trans-76.5148.6176.351.30000111.4D179 K180T177-D179 WeakPolarHBondContact CB-OD1 3.44Å; T177-D179 PolarHBondContact O-N 3.11Å; T177-D179 PolarHBondContact OG1-OD1 2.92Å; T177-K180 WeakPolarHBondContact O-CB 3.46Å; T177-K180 PolarHBondContact O-N 2.82Å
178P97.6Very high98Very high23 Ų2328.2 Ų28.215%0.14916%0.161CC..G310 helixtrans-54.7-30.1-175.2-29.335.9000115.3I168 K180 L181 W216 N220 M221I168-P178 HydrophobicContact CG2-CG 4.19Å; P178-K180 PolarHBondContact O-N 3.37Å; P178-L181 WeakPolarHBondContact O-CB 3.41Å; P178-L181 PolarHBondContact O-N 2.88Å; P178-L181 VanDerWaalsContact O-N 3.12Å; P178-W216 HydrophobicContact CB-CH2 4.33Å; P178-W216 HydrophobicContact CG-CH2 4.41Å; P178-N220 CarbonylContact C-O 3.57Å; P178-M221 HydrophobicContact CB-CG 3.73Å
179D97.4Very high98Very high69 Ų6928.5 Ų28.537%0.36916%0.162SC..G310 helixtrans-66.9-18.5-179.868.3-65.9000114.1T177 N220 R223T177-D179 WeakPolarHBondContact CB-OD1 3.44Å; T177-D179 PolarHBondContact O-N 3.11Å; T177-D179 PolarHBondContact OG1-OD1 2.92Å; D179-N220 WeakPolarHBondContact CA-O 3.45Å; D179-N220 PolarHBondContact N-O 3.07Å; D179-R223 WeakPolarHBondContact O-CD 3.27Å
180K97.6Very high97.9Very high88 Ų8828.5 Ų28.538%0.38316%0.162SC..G310 helixtrans-88.9-15.7176.9-63179.6-175.11730113V176 T177 P178 T182V176-K180 HydrophobicContact CG1-CB 3.9Å; V176-K180 HydrophobicContact CG1-CD 4.47Å; T177-K180 WeakPolarHBondContact O-CB 3.46Å; T177-K180 PolarHBondContact O-N 2.82Å; P178-K180 PolarHBondContact O-N 3.37Å; K180-T182 PolarHBondContact O-N 3.49Å
181L98Very high97.9Very high0 Ų028.5 Ų28.50%016%0.162CC..  trans-69.9129.1-176.4-63.2175.2000111L147 Y167 A171 V176 P178 M221L147-L181 HydrophobicContact CB-CD2 3.96Å; Y167-L181 HydrophobicContact CD1-CD1 4.35Å; Y167-L181 HydrophobicContact CE1-CB 4.27Å; Y167-L181 HydrophobicContact CE1-CD1 3.82Å; Y167-L181 HydrophobicContact CE1-CD2 4.35Å; Y167-L181 HydrophobicContact CE1-CG 4.37Å; A171-L181 HydrophobicContact CB-CD1 3.81Å; A171-L181 HydrophobicContact CB-CD2 3.59Å; A171-L181 HydrophobicContact CB-CG 4.23Å; V176-L181 HydrophobicContact CG1-CD2 3.89Å; V176-L181 HydrophobicContact CG1-CG 4.47Å; P178-L181 WeakPolarHBondContact O-CB 3.41Å; P178-L181 PolarHBondContact O-N 2.88Å; P178-L181 VanDerWaalsContact O-N 3.12Å; L181-M221 HydrophobicContact CB-CE 3.87Å; L181-M221 HydrophobicContact CD1-CE 3.89Å
182T96.6Very high97.8Very high39 Ų3928.5 Ų28.524%0.23916%0.162CC..EExtended strand (participates in β ladder)trans-119136.6175.868.90000108.7M150 S151 V152 K180 R223M150-T182 PolarHBondContact O-OG1 3.23Å; S151-T182 WeakPolarHBondContact CA-O 3.43Å; S151-T182 WeakPolarHBondContact CA-OG1 3.48Å; V152-T182 PolarHBondContact N-O 2.92Å; V152-T182 VanDerWaalsContact N-O 3.09Å; K180-T182 PolarHBondContact O-N 3.49Å; T182-R223 HydrophobicContact CG2-CB 4.05Å
183G95.8Very high97.6Very high2 Ų226.3 Ų26.32%0.02115%0.151CC..EExtended strand (participates in β ladder)trans163.9-169.7-171.400000113.5V152 N225V152-G183 CarbonylContact O-C 3.38Å; V152-G183 WeakPolarHBondContact O-CA 3.45Å; G183-N225 PolarHBondContact O-N 2.78Å; G183-N225 PolarHBondContact O-ND2 3.19Å
184T97.9Very high97.3Very high10 Ų1022.5 Ų22.56%0.06113%0.134CC..EExtended strand (participates in β ladder)trans-149.3130.7179.5-55.50000108.8V152 S153 M154 N225V152-T184 PolarHBondContact O-N 2.95Å; S153-T184 CarbonylContact C-O 3.47Å; S153-T184 VanDerWaalsContact CA-O 3.28Å; S153-T184 WeakPolarHBondContact CA-O 3.47Å; M154-T184 PolarHBondContact N-O 3.19Å; T184-N225 WeakPolarHBondContact CA-O 3.49Å; T184-N225 HydrophobicContact CG2-CB 3.94Å; T184-N225 WeakPolarHBondContact OG1-CB 3.23Å; T184-N225 PolarHBondContact OG1-ND2 3.06Å
185I98.4Very high97Very high0 Ų019.7 Ų19.70%012%0.122CC..EExtended strand (participates in β ladder)trans-100.9138.3164.5-172.265.8000107.6M154 M156 V160 N187 F224 N225 T226 I227 S228M154-I185 HydrophobicContact CB-CD1 3.67Å; M154-I185 HydrophobicContact CE-CD1 4.28Å; M156-I185 HydrophobicContact CB-CD1 3.91Å; V160-I185 HydrophobicContact CG2-CD1 4.07Å; V160-I185 HydrophobicContact CG2-CG1 3.53Å; I185-N187 HydrophobicContact CG1-CB 4.14Å; I185-N187 HydrophobicContact CG2-CB 3.86Å; I185-F224 HydrophobicContact CB-CE1 3.77Å; I185-F224 HydrophobicContact CB-CZ 4.13Å; I185-F224 HydrophobicContact CG2-CE1 3.67Å; I185-N225 PolarHBondContact N-O 2.9Å; I185-T226 VanDerWaalsContact CG2-O 3.26Å; I185-T226 WeakPolarHBondContact CG2-O 3.36Å; I185-I227 CarbonylContact O-C 3.57Å; I185-I227 WeakPolarHBondContact O-CA 3.3Å; I185-S228 PolarHBondContact O-N 3.32Å
186Q98.5Very high96.9Very high5 Ų518.7 Ų18.72%0.02310%0.098CC..  trans-64.9-52.6-177.8-170.9175.888.300111.3M154 N157 D188 I227 S228 H233M154-Q186 PolarHBondContact O-N 3.36Å; N157-Q186 PolarHBondContact ND2-OE1 3.41Å; N157-Q186 WeakPolarHBondContact OD1-CB 3.44Å; N157-Q186 VanDerWaalsContact OD1-CG 3.26Å; N157-Q186 WeakPolarHBondContact OD1-CG 3.22Å; N157-Q186 PolarHBondContact OD1-OE1 3.31Å; N157-Q186 VanDerWaalsContact OD1-OE1 3.09Å; Q186-D188 HydrophobicContact CG-CB 4.44Å; Q186-D188 PolarHBondContact O-N 3.32Å; Q186-I227 WeakPolarHBondContact O-CG1 3.46Å; Q186-S228 PolarHBondContact O-N 3.35Å; Q186-H233 PolarHBondContact NE2-CE1 2.87Å; Q186-H233 VanDerWaalsContact NE2-CE1 3.32Å
187N98.6Very high96.8Very high3 Ų318.5 Ų18.52%0.01610%0.097CC..  trans48.333.3166.5-166.134.8000114.8M156 N157 V160 I185 I210 I213 T226 I227M156-N187 PolarHBondContact O-N 3.36Å; N157-N187 PolarHBondContact OD1-N 2.98Å; V160-N187 HydrophobicContact CG2-CB 4.04Å; I185-N187 HydrophobicContact CG1-CB 4.14Å; I185-N187 HydrophobicContact CG2-CB 3.86Å; N187-I210 WeakPolarHBondContact O-CD1 3.45Å; N187-I210 WeakPolarHBondContact OD1-CG1 3.32Å; N187-I213 WeakPolarHBondContact OD1-CD1 3.42Å; N187-T226 PolarHBondContact ND2-O 3.18Å; N187-I227 HydrophobicContact CB-CG1 4.43Å; N187-I227 WeakPolarHBondContact O-CD1 3.48Å; N187-I227 WeakPolarHBondContact O-CG1 3.32Å
188D98.5Very high96.8Very high0 Ų015.7 Ų15.70%08%0.08CC..  trans-114.394.9-176.5179.8-4.9000108.1N157 Q186 K191 I227 I229 S230 Y255N157-D188 PolarHBondContact OD1-N 3.1Å; N157-D188 PolarHBondContact OD1-O 3.32Å; Q186-D188 HydrophobicContact CG-CB 4.44Å; Q186-D188 PolarHBondContact O-N 3.32Å; D188-K191 HydrophobicContact CB-CG 4.14Å; D188-K191 VanDerWaalsContact CG-CG 3.48Å; D188-K191 WeakPolarHBondContact O-CG 3.45Å; D188-K191 PolarHBondContact O-NZ 3.41Å; D188-I227 HydrophobicContact CB-CD1 4.5Å; D188-I227 HydrophobicContact CB-CG1 4.34Å; D188-I229 WeakPolarHBondContact OD2-CA 3.26Å; D188-S230 WeakPolarHBondContact OD2-CB 3.36Å; D188-S230 PolarHBondContact OD2-N 3.08Å; D188-Y255 WeakPolarHBondContact CA-OH 3.49Å; D188-Y255 WeakPolarHBondContact OD1-CE2 3.39Å; D188-Y255 PolarHBondContact OD1-OH 3.19Å
189I97.9Very high96.8Very high7 Ų714.9 Ų14.94%0.0367%0.074CC..  trans-84.4-27.9-174.5-158.678.8000113K191 E192 Y193 M207 I210 Y255I189-K191 PolarHBondContact O-N 3.28Å; I189-E192 HydrophobicContact CD1-CB 4.27Å; I189-E192 HydrophobicContact CD1-CG 4Å; I189-E192 WeakPolarHBondContact O-CA 3.47Å; I189-E192 WeakPolarHBondContact O-CB 3.35Å; I189-E192 PolarHBondContact O-N 3.46Å; I189-Y193 HydrophobicContact CB-CE2 4.29Å; I189-Y193 HydrophobicContact CG1-CD2 4.43Å; I189-Y193 HydrophobicContact CG1-CE2 3.56Å; I189-Y193 HydrophobicContact CG2-CE2 4.04Å; I189-Y193 WeakPolarHBondContact O-CD2 3.18Å; I189-Y193 WeakPolarHBondContact O-CE2 3.36Å; I189-Y193 PolarHBondContact O-N 3.24Å; I189-M207 HydrophobicContact CG2-SD 4.01Å; I189-I210 HydrophobicContact CB-CD1 3.92Å; I189-I210 HydrophobicContact CG2-CD1 3.44Å; I189-I210 VanDerWaalsContact CG2-CD1 3.44Å; I189-Y255 PolarHBondContact N-OH 2.96Å
190L97.4Very high96.8Very high1 Ų111.7 Ų11.71%0.0056%0.057CC..Hα-helixtrans-60.6-44.8-176.6-66.8177.1000111.3E192 Y193 L194 M207 D251 E254 Y255 A423 I426L190-E192 VanDerWaalsContact C-N 3.26Å; L190-E192 PolarHBondContact O-N 3.2Å; L190-Y193 PolarHBondContact O-N 3.42Å; L190-L194 PolarHBondContact O-N 3.32Å; L190-M207 HydrophobicContact CD1-CE 4.4Å; L190-M207 HydrophobicContact CD1-SD 4.21Å; L190-M207 HydrophobicContact CD2-CG 4.5Å; L190-M207 HydrophobicContact CD2-SD 3.77Å; L190-M207 HydrophobicContact CG-SD 3.88Å; L190-D251 HydrophobicContact CB-CB 4.49Å; L190-D251 VanDerWaalsContact CB-OD1 3.26Å; L190-D251 WeakPolarHBondContact CB-OD1 3.34Å; L190-D251 HydrophobicContact CD1-CB 4.11Å; L190-D251 WeakPolarHBondContact CD1-OD1 3.47Å; L190-E254 HydrophobicContact CD1-CB 3.89Å; L190-E254 HydrophobicContact CD1-CG 4.09Å; L190-Y255 WeakPolarHBondContact CB-OH 3.43Å; L190-Y255 HydrophobicContact CD1-CE1 3.95Å; L190-Y255 HydrophobicContact CD1-CE2 4.2Å; L190-Y255 HydrophobicContact CG-CE1 4.01Å; L190-Y255 WeakPolarHBondContact CG-OH 3.36Å; L190-Y255 PolarHBondContact N-OH 3.25Å; L190-A423 HydrophobicContact CD2-CB 4.44Å; L190-I426 HydrophobicContact CB-CD1 3.85Å; L190-I426 HydrophobicContact CD2-CD1 3.82Å; L190-I426 HydrophobicContact CG-CD1 4.36Å
191K97.5Very high96.8Very high0 Ų07.7 Ų7.70%04%0.039CC..Hα-helixtrans-65-22.4171.663.9130.317064.10114.9N157 D188 I189 Y193 L194 C195 R196 H233 M234N157-K191 PolarHBondContact ND2-NZ 3.2Å; N157-K191 PolarHBondContact OD1-NZ 3.44Å; D188-K191 HydrophobicContact CB-CG 4.14Å; D188-K191 VanDerWaalsContact CG-CG 3.48Å; D188-K191 WeakPolarHBondContact O-CG 3.45Å; D188-K191 PolarHBondContact O-NZ 3.41Å; I189-K191 PolarHBondContact O-N 3.28Å; K191-Y193 VanDerWaalsContact C-N 3.3Å; K191-L194 PolarHBondContact O-N 3.35Å; K191-C195 PolarHBondContact O-N 3.02Å; K191-C195 PolarHBondContact O-SG 3.18Å; K191-C195 VanDerWaalsContact O-SG 3.4Å; K191-R196 PolarHBondContact O-N 3.26Å; K191-H233 HydrophobicContact CD-CB 4.24Å; K191-H233 VanDerWaalsContact CD-ND1 3.26Å; K191-H233 WeakPolarHBondContact CD-ND1 3.35Å; K191-H233 VanDerWaalsContact CE-CE1 3.46Å; K191-H233 WeakPolarHBondContact CE-CE1 3.49Å; K191-H233 WeakPolarHBondContact CE-ND1 2.89Å; K191-M234 HydrophobicContact CB-CE 3.85Å
192E96.8Very high96.6Very high0 Ų09.2 Ų9.20%05%0.049CC..Iπ-helixtrans-64.6-40.5175-61.8-61.9154.800110.7N157 I189 L190 L194 R196 N197 T198 Y199N157-E192 HydrophobicContact CB-CG 3.81Å; N157-E192 WeakPolarHBondContact CB-OE1 3.41Å; N157-E192 PolarHBondContact ND2-OE1 3.04Å; I189-E192 HydrophobicContact CD1-CB 4.27Å; I189-E192 HydrophobicContact CD1-CG 4Å; I189-E192 WeakPolarHBondContact O-CA 3.47Å; I189-E192 WeakPolarHBondContact O-CB 3.35Å; I189-E192 PolarHBondContact O-N 3.46Å; L190-E192 VanDerWaalsContact C-N 3.26Å; L190-E192 PolarHBondContact O-N 3.2Å; E192-L194 VanDerWaalsContact C-N 3.28Å; E192-L194 PolarHBondContact O-N 3.42Å; E192-R196 VanDerWaalsContact OE1-CD 3.25Å; E192-R196 WeakPolarHBondContact OE1-CD 3.45Å; E192-R196 IonicContact OE1-NH1 3.28Å; E192-R196 VanDerWaalsContact OE2-CB 3.27Å; E192-R196 WeakPolarHBondContact OE2-CB 3.48Å; E192-R196 WeakPolarHBondContact OE2-CG 3.43Å; E192-N197 WeakPolarHBondContact O-CA 3.36Å; E192-N197 PolarHBondContact O-N 2.9Å; E192-T198 PolarHBondContact OE1-OG1 2.89Å; E192-T198 WeakPolarHBondContact OE2-CA 3.41Å; E192-T198 WeakPolarHBondContact OE2-CB 3.31Å; E192-T198 PolarHBondContact OE2-N 3.1Å; E192-T198 PolarHBondContact OE2-OG1 2.98Å; E192-Y199 HydrophobicContact CB-CD1 4.08Å; E192-Y199 WeakPolarHBondContact O-CD1 3.47Å
193Y93.8Very high96.3Very high16 Ų168 Ų86%0.0634%0.041CC..Iπ-helixtrans-72.1-23.1177.3-56.1-61.7000112.9I189 L190 K191 Y199 Y201 P202 P203 S206 Y542I189-Y193 HydrophobicContact CB-CE2 4.29Å; I189-Y193 HydrophobicContact CG1-CD2 4.43Å; I189-Y193 HydrophobicContact CG1-CE2 3.56Å; I189-Y193 HydrophobicContact CG2-CE2 4.04Å; I189-Y193 WeakPolarHBondContact O-CD2 3.18Å; I189-Y193 WeakPolarHBondContact O-CE2 3.36Å; I189-Y193 PolarHBondContact O-N 3.24Å; L190-Y193 PolarHBondContact O-N 3.42Å; K191-Y193 VanDerWaalsContact C-N 3.3Å; Y193-Y199 AromaticContact CD1-CD1 3.5Å; Y193-Y199 HydrophobicContact CD1-CD1 3.5Å; Y193-Y199 HydrophobicContact CD1-CD2 4.44Å; Y193-Y199 HydrophobicContact CD1-CE1 4.09Å; Y193-Y199 AromaticContact CD1-CG 3.72Å; Y193-Y199 HydrophobicContact CD1-CG 3.72Å; Y193-Y199 VanDerWaalsContact CE1-CB 3.48Å; Y193-Y199 AromaticContact CE1-CD1 3.92Å; Y193-Y199 HydrophobicContact CE1-CD1 3.92Å; Y193-Y199 HydrophobicContact CE1-CD2 4.23Å; Y193-Y199 AromaticContact CE1-CG 3.61Å; Y193-Y199 HydrophobicContact CE1-CG 3.61Å; Y193-Y199 HydrophobicContact CG-CD1 4.35Å; Y193-Y201 PolarHBondContact OH-O 3.39Å; Y193-P202 PolarHBondContact OH-O 3.15Å; Y193-P203 HydrophobicContact CD2-CG 4.26Å; Y193-P203 HydrophobicContact CE1-CG 4.21Å; Y193-P203 HydrophobicContact CE2-CB 3.99Å; Y193-P203 HydrophobicContact CE2-CG 3.95Å; Y193-P203 WeakPolarHBondContact OH-CA 3.27Å; Y193-S206 WeakPolarHBondContact OH-CB 3.35Å; Y193-S206 PolarHBondContact OH-OG 2.92Å; Y193-Y542 AromaticContact CD1-CD1 3.7Å; Y193-Y542 HydrophobicContact CD1-CD1 3.7Å; Y193-Y542 AromaticContact CD1-CE1 3.57Å; Y193-Y542 HydrophobicContact CD1-CE1 3.57Å; Y193-Y542 AromaticContact CE1-CD1 3.51Å; Y193-Y542 HydrophobicContact CE1-CD1 3.51Å; Y193-Y542 AromaticContact CE1-CE1 3.78Å; Y193-Y542 HydrophobicContact CE1-CE1 3.78Å; Y193-Y542 HydrophobicContact CE1-CG 4.29Å
194L93Very high96.2Very high3 Ų316.6 Ų16.62%0.0168%0.078CC..Iπ-helixtrans-82.7-51.1179.3-70.6177000113.2L190 K191 E192 M234 M422 I426 P431 K432L190-L194 PolarHBondContact O-N 3.32Å; K191-L194 PolarHBondContact O-N 3.35Å; E192-L194 VanDerWaalsContact C-N 3.28Å; E192-L194 PolarHBondContact O-N 3.42Å; L194-M234 HydrophobicContact CD1-CE 4.05Å; L194-M422 HydrophobicContact CD1-CE 3.54Å; L194-I426 HydrophobicContact CD1-CD1 4.35Å; L194-I426 HydrophobicContact CD1-CG1 4.29Å; L194-I426 HydrophobicContact CD2-CD1 4.46Å; L194-I426 HydrophobicContact CD2-CG1 3.66Å; L194-I426 HydrophobicContact CG-CD1 4.19Å; L194-I426 HydrophobicContact CG-CG1 3.92Å; L194-P431 HydrophobicContact CD1-CB 4.34Å; L194-P431 HydrophobicContact CD2-CB 3.79Å; L194-P431 HydrophobicContact CD2-CG 4.24Å; L194-K432 HydrophobicContact CD2-CB 4.14Å; L194-K432 PolarHBondContact O-NZ 3.41Å
195C92.4Very high96Very high12 Ų1217.1 Ų17.18%0.0818%0.082CC..Iπ-helixtrans-147.1-23.6-165.456.50000116.9K191 H233 A237K191-C195 PolarHBondContact O-N 3.02Å; K191-C195 PolarHBondContact O-SG 3.18Å; K191-C195 VanDerWaalsContact O-SG 3.4Å; C195-H233 PolarHBondContact SG-O 3.19Å; C195-A237 HydrophobicContact CB-CB 3.55Å
196R95.4Very high95.9Very high43 Ų4317.3 Ų17.316%0.1628%0.083CC..Iπ-helixtrans-95.9-22.8-172.8-167.6179.5-169-83.9-2.7114.3H111 K191 E192 T198 H233H111-R196 PolarHBondContact CE1-NH1 3.2Å; H111-R196 PolarHBondContact CE1-NH2 3.48Å; H111-R196 PolarHBondContact ND1-NH1 3.15Å; H111-R196 PolarHBondContact NE2-NH2 3.26Å; K191-R196 PolarHBondContact O-N 3.26Å; E192-R196 VanDerWaalsContact OE1-CD 3.25Å; E192-R196 WeakPolarHBondContact OE1-CD 3.45Å; E192-R196 IonicContact OE1-NH1 3.28Å; E192-R196 VanDerWaalsContact OE2-CB 3.27Å; E192-R196 WeakPolarHBondContact OE2-CB 3.48Å; E192-R196 WeakPolarHBondContact OE2-CG 3.43Å; R196-T198 VanDerWaalsContact C-N 3.32Å; R196-T198 PolarHBondContact NH1-OG1 3.32Å; R196-T198 PolarHBondContact O-N 2.94Å; R196-H233 HydrophobicContact CB-CB 4.3Å; R196-H233 WeakPolarHBondContact CD-CD2 3.44Å; R196-H233 WeakPolarHBondContact CD-NE2 3.27Å; R196-H233 PolarHBondContact NE-CD2 2.9Å; R196-H233 PolarHBondContact NE-NE2 3.5Å
197N96Very high95.8Very high5 Ų518.2 Ų18.23%0.0279%0.088CC..  trans56.535170.8-61.5-46.8000115.3E192 Y199 G596 D598 M620 F621E192-N197 WeakPolarHBondContact O-CA 3.36Å; E192-N197 PolarHBondContact O-N 2.9Å; N197-Y199 HydrophobicContact CB-CE1 4.35Å; N197-G596 PolarHBondContact ND2-O 2.87Å; N197-D598 PolarHBondContact ND2-OD2 3.48Å; N197-M620 HydrophobicContact CB-CE 4.12Å; N197-F621 HydrophobicContact CB-CZ 4.26Å; N197-F621 WeakPolarHBondContact O-CE1 3.43Å; N197-F621 WeakPolarHBondContact O-CZ 3.21Å
198T97.6Very high95.6Very high3 Ų320.2 Ų20.22%0.01810%0.095CC..  trans-111.526.6171.266.30000113.1L108 H111 G158 E192 R196L108-T198 HydrophobicContact CD2-CG2 4.27Å; H111-T198 HydrophobicContact CB-CG2 4.18Å; G158-T198 VanDerWaalsContact CA-O 3.26Å; G158-T198 WeakPolarHBondContact CA-O 3.46Å; E192-T198 PolarHBondContact OE1-OG1 2.89Å; E192-T198 WeakPolarHBondContact OE2-CA 3.41Å; E192-T198 WeakPolarHBondContact OE2-CB 3.31Å; E192-T198 PolarHBondContact OE2-N 3.1Å; E192-T198 PolarHBondContact OE2-OG1 2.98Å; R196-T198 VanDerWaalsContact C-N 3.32Å; R196-T198 PolarHBondContact NH1-OG1 3.32Å; R196-T198 PolarHBondContact O-N 2.94Å
199Y96.9Very high95.6Very high7 Ų720.5 Ų20.53%0.02710%0.096CC..  trans-69.8154.3170.550.4-102000112R112 E192 Y193 N197 Y542 F621R112-Y199 PolarHBondContact NE-O 2.95Å; R112-Y199 PolarHBondContact NH2-O 3.04Å; E192-Y199 HydrophobicContact CB-CD1 4.08Å; E192-Y199 WeakPolarHBondContact O-CD1 3.47Å; Y193-Y199 AromaticContact CD1-CD1 3.5Å; Y193-Y199 HydrophobicContact CD1-CD1 3.5Å; Y193-Y199 HydrophobicContact CD1-CD2 4.44Å; Y193-Y199 HydrophobicContact CD1-CE1 4.09Å; Y193-Y199 AromaticContact CD1-CG 3.72Å; Y193-Y199 HydrophobicContact CD1-CG 3.72Å; Y193-Y199 VanDerWaalsContact CE1-CB 3.48Å; Y193-Y199 AromaticContact CE1-CD1 3.92Å; Y193-Y199 HydrophobicContact CE1-CD1 3.92Å; Y193-Y199 HydrophobicContact CE1-CD2 4.23Å; Y193-Y199 AromaticContact CE1-CG 3.61Å; Y193-Y199 HydrophobicContact CE1-CG 3.61Å; Y193-Y199 HydrophobicContact CG-CD1 4.35Å; N197-Y199 HydrophobicContact CB-CE1 4.35Å; Y199-Y542 AromaticContact CD2-CD1 3.82Å; Y199-Y542 HydrophobicContact CD2-CD1 3.82Å; Y199-Y542 HydrophobicContact CD2-CG 4.49Å; Y199-Y542 AromaticContact CE2-CD1 3.79Å; Y199-Y542 HydrophobicContact CE2-CD1 3.79Å; Y199-Y542 WeakPolarHBondContact CE2-O 3.21Å; Y199-Y542 HydrophobicContact CG-CD1 4.36Å; Y199-F621 HydrophobicContact CE2-CE2 4.08Å
200I98Very high95.5Very high2 Ų220.3 Ų20.31%0.0110%0.095CC..  trans-115.2-62.1171.5-54.7176.3000108.7R112 A159 R541 Y542R112-I200 WeakPolarHBondContact O-CD1 3.12Å; R112-I200 WeakPolarHBondContact O-CG1 3.28Å; A159-I200 HydrophobicContact CB-CD1 4.06Å; I200-R541 HydrophobicContact CG2-CG 4.28Å; I200-R541 CarbonylContact O-C 3.6Å; I200-R541 WeakPolarHBondContact O-CA 3.35Å; I200-R541 WeakPolarHBondContact O-CG 3.33Å; I200-Y542 PolarHBondContact O-N 2.89Å
201Y97.4Very high95.5Very high4 Ų420.6 Ų20.62%0.01610%0.098CC..SBendtrans-93.4163.9-173.9-38.3-69.1000112.6Y193 S206 I209 S532 L535 E536 F539Y193-Y201 PolarHBondContact OH-O 3.39Å; Y201-S206 PolarHBondContact O-OG 3.24Å; Y201-I209 HydrophobicContact CD2-CD1 3.48Å; Y201-I209 VanDerWaalsContact CD2-CD1 3.48Å; Y201-I209 HydrophobicContact CE2-CD1 3.62Å; Y201-S532 WeakPolarHBondContact OH-CA 3.46Å; Y201-S532 PolarHBondContact OH-O 3.42Å; Y201-L535 HydrophobicContact CE1-CB 3.84Å; Y201-L535 HydrophobicContact CE2-CD1 4.32Å; Y201-L535 WeakPolarHBondContact OH-CD1 3.46Å; Y201-E536 HydrophobicContact CE1-CB 4.32Å; Y201-F539 HydrophobicContact CD1-CB 4.06Å; Y201-F539 HydrophobicContact CD1-CD2 4.33Å; Y201-F539 HydrophobicContact CG-CB 4.32Å; Y201-F539 HydrophobicContact CG-CD2 4.26Å
202P94.1Very high95.4Very high31 Ų3121.6 Ų21.620%0.20110%0.103CC..  trans-60.8162.1174.5-24.833.8000113.6Y193 K204 P205 S206 F539 D540 Y542Y193-P202 PolarHBondContact OH-O 3.15Å; P202-K204 PolarHBondContact O-N 3.33Å; P202-P205 HydrophobicContact CB-CG 4.07Å; P202-P205 HydrophobicContact CG-CG 4.34Å; P202-P205 WeakPolarHBondContact O-CD 3.47Å; P202-P205 VanDerWaalsContact O-CG 3.27Å; P202-P205 WeakPolarHBondContact O-CG 3.39Å; P202-S206 WeakPolarHBondContact O-CB 3.35Å; P202-S206 PolarHBondContact O-N 2.88Å; P202-S206 VanDerWaalsContact O-N 3.16Å; P202-S206 PolarHBondContact O-OG 3.02Å; P202-F539 WeakPolarHBondContact CD-O 3.39Å; P202-F539 WeakPolarHBondContact CG-O 2.85Å; P202-D540 VanDerWaalsContact CD-O 3.31Å; P202-D540 WeakPolarHBondContact CD-O 3.44Å; P202-Y542 HydrophobicContact CB-CD2 3.93Å; P202-Y542 HydrophobicContact CG-CD2 4.15Å
203P91.4Very high95.5Very high13 Ų1321.6 Ų21.68%0.08410%0.103CC..Hα-helixtrans-53.4-46.3-174.1-29.935.6000114.7Y193 S206 M207Y193-P203 HydrophobicContact CD2-CG 4.26Å; Y193-P203 HydrophobicContact CE1-CG 4.21Å; Y193-P203 HydrophobicContact CE2-CB 3.99Å; Y193-P203 HydrophobicContact CE2-CG 3.95Å; Y193-P203 WeakPolarHBondContact OH-CA 3.27Å; P203-S206 PolarHBondContact O-N 3.4Å; P203-M207 VanDerWaalsContact O-CG 3.31Å; P203-M207 WeakPolarHBondContact O-CG 3.36Å; P203-M207 PolarHBondContact O-N 2.99Å
204K92.1Very high95.7Very high184 Ų18420.9 Ų20.980%0.810%0.101SC*.Hα-helixtrans-61.6-55.5-177-175.2-177.6-179.5-175.70113.8P202 S206 M207 R208P202-K204 PolarHBondContact O-N 3.33Å; K204-S206 VanDerWaalsContact C-N 3.29Å; K204-S206 PolarHBondContact O-N 3.1Å; K204-M207 PolarHBondContact O-N 2.94Å; K204-R208 PolarHBondContact O-N 3.01Å
205P94.9Very high95.8Very high20 Ų2022.5 Ų22.513%0.1311%0.114CC..Hα-helixtrans-62.7-34.517621.9-31.6000112.6P202 M207 R208 I209 F539P202-P205 HydrophobicContact CB-CG 4.07Å; P202-P205 HydrophobicContact CG-CG 4.34Å; P202-P205 WeakPolarHBondContact O-CD 3.47Å; P202-P205 VanDerWaalsContact O-CG 3.27Å; P202-P205 WeakPolarHBondContact O-CG 3.39Å; P205-M207 PolarHBondContact O-N 3.5Å; P205-R208 WeakPolarHBondContact O-CB 3.35Å; P205-R208 PolarHBondContact O-N 3Å; P205-I209 WeakPolarHBondContact O-CG1 3.42Å; P205-I209 PolarHBondContact O-N 2.75Å; P205-F539 HydrophobicContact CB-CB 3.81Å; P205-F539 HydrophobicContact CB-CD1 3.57Å; P205-F539 HydrophobicContact CB-CD2 3.72Å; P205-F539 HydrophobicContact CB-CE1 4.01Å; P205-F539 HydrophobicContact CB-CE2 4.13Å; P205-F539 HydrophobicContact CB-CG 3.42Å; P205-F539 VanDerWaalsContact CB-CG 3.42Å; P205-F539 HydrophobicContact CB-CZ 4.27Å; P205-F539 HydrophobicContact CG-CB 3.93Å; P205-F539 HydrophobicContact CG-CD1 4.43Å; P205-F539 HydrophobicContact CG-CG 4.12Å
206S96.3Very high96Very high4 Ų423.8 Ų23.83%0.02812%0.117CC..Hα-helixtrans-65-39.2176-59.30000113.5Y193 Y201 P202 P203 K204 R208 I209 I210Y193-S206 WeakPolarHBondContact OH-CB 3.35Å; Y193-S206 PolarHBondContact OH-OG 2.92Å; Y201-S206 PolarHBondContact O-OG 3.24Å; P202-S206 WeakPolarHBondContact O-CB 3.35Å; P202-S206 PolarHBondContact O-N 2.88Å; P202-S206 VanDerWaalsContact O-N 3.16Å; P202-S206 PolarHBondContact O-OG 3.02Å; P203-S206 PolarHBondContact O-N 3.4Å; K204-S206 VanDerWaalsContact C-N 3.29Å; K204-S206 PolarHBondContact O-N 3.1Å; S206-R208 VanDerWaalsContact C-N 3.26Å; S206-R208 PolarHBondContact O-N 2.81Å; S206-I209 WeakPolarHBondContact O-CB 3.18Å; S206-I209 PolarHBondContact O-N 2.99Å; S206-I209 VanDerWaalsContact O-N 3.17Å; S206-I210 PolarHBondContact O-N 3.23Å; S206-I210 VanDerWaalsContact O-N 3.13Å
207M95Very high96Very high24 Ų2421.8 Ų21.812%0.11811%0.11CC..Hα-helixtrans-63.6-33.9173.6-71.6-59.4-67.200112.1I189 L190 P203 K204 P205 I210 A211 E254 Y255 A258I189-M207 HydrophobicContact CG2-SD 4.01Å; L190-M207 HydrophobicContact CD1-CE 4.4Å; L190-M207 HydrophobicContact CD1-SD 4.21Å; L190-M207 HydrophobicContact CD2-CG 4.5Å; L190-M207 HydrophobicContact CD2-SD 3.77Å; L190-M207 HydrophobicContact CG-SD 3.88Å; P203-M207 VanDerWaalsContact O-CG 3.31Å; P203-M207 WeakPolarHBondContact O-CG 3.36Å; P203-M207 PolarHBondContact O-N 2.99Å; K204-M207 PolarHBondContact O-N 2.94Å; P205-M207 PolarHBondContact O-N 3.5Å; M207-I210 PolarHBondContact O-N 3.34Å; M207-I210 HydrophobicContact SD-CD1 4.27Å; M207-A211 PolarHBondContact O-N 2.87Å; M207-A211 VanDerWaalsContact O-N 3.1Å; M207-E254 HydrophobicContact CE-CG 4.26Å; M207-Y255 HydrophobicContact CE-CD1 3.55Å; M207-Y255 HydrophobicContact CE-CE1 3.71Å; M207-Y255 HydrophobicContact SD-CD1 4.07Å; M207-Y255 HydrophobicContact SD-CE1 3.58Å; M207-Y255 VanDerWaalsContact SD-CE1 3.58Å; M207-A258 HydrophobicContact CE-CB 3.8Å
208R95.1Very high95.9Very high46 Ų4623.2 Ų23.217%0.17412%0.12CC..Hα-helixtrans-63.8-45171.4175.9-175165-166.6-12.5111.5K204 P205 S206 I210 A211 D212 A507 A508 N511 E512K204-R208 PolarHBondContact O-N 3.01Å; P205-R208 WeakPolarHBondContact O-CB 3.35Å; P205-R208 PolarHBondContact O-N 3Å; S206-R208 VanDerWaalsContact C-N 3.26Å; S206-R208 PolarHBondContact O-N 2.81Å; R208-I210 PolarHBondContact O-N 2.88Å; R208-A211 PolarHBondContact O-N 3Å; R208-A211 VanDerWaalsContact O-N 3.12Å; R208-D212 IonicContact NE-OD2 3.74Å; R208-D212 PolarHBondContact O-N 3.24Å; R208-A507 PolarHBondContact NH2-O 2.84Å; R208-A508 PolarHBondContact NH1-O 2.79Å; R208-N511 PolarHBondContact NH1-OD1 3.49Å; R208-N511 VanDerWaalsContact NH2-CA 3.32Å; R208-E512 PolarHBondContact NH2-O 3.16Å; R208-E512 VanDerWaalsContact NH2-O 3.13Å
209I97.8Very high95.6Very high5 Ų526 Ų263%0.02615%0.149CC..Hα-helixtrans-54.4-44.6176.9-69.6169.9000110.6V160 L161 Y201 P205 S206 D212 I213 L514 F539V160-I209 HydrophobicContact CG1-CG2 3.74Å; L161-I209 HydrophobicContact CD1-CB 4.45Å; L161-I209 HydrophobicContact CD1-CD1 4.08Å; L161-I209 HydrophobicContact CD1-CG1 3.93Å; L161-I209 HydrophobicContact CD1-CG2 3.76Å; L161-I209 HydrophobicContact CD2-CG2 4.17Å; L161-I209 HydrophobicContact CG-CG2 3.69Å; Y201-I209 HydrophobicContact CD2-CD1 3.48Å; Y201-I209 VanDerWaalsContact CD2-CD1 3.48Å; Y201-I209 HydrophobicContact CE2-CD1 3.62Å; P205-I209 WeakPolarHBondContact O-CG1 3.42Å; P205-I209 PolarHBondContact O-N 2.75Å; S206-I209 WeakPolarHBondContact O-CB 3.18Å; S206-I209 PolarHBondContact O-N 2.99Å; S206-I209 VanDerWaalsContact O-N 3.17Å; I209-D212 PolarHBondContact O-N 2.95Å; I209-I213 HydrophobicContact CG2-CD1 3.84Å; I209-I213 WeakPolarHBondContact O-CG1 3.45Å; I209-I213 PolarHBondContact O-N 2.74Å; I209-L514 HydrophobicContact CG1-CD1 3.7Å; I209-F539 HydrophobicContact CD1-CE2 4.24Å; I209-F539 HydrophobicContact CG1-CE2 4.38Å
210I97.4Very high95.6Very high3 Ų329.2 Ų29.22%0.01517%0.167CC..Hα-helixtrans-61.7-47.2177.5-65.8172.4000111N187 I189 S206 M207 R208 D212 I213 I214 I227 Y255N187-I210 WeakPolarHBondContact O-CD1 3.45Å; N187-I210 WeakPolarHBondContact OD1-CG1 3.32Å; I189-I210 HydrophobicContact CB-CD1 3.92Å; I189-I210 HydrophobicContact CG2-CD1 3.44Å; I189-I210 VanDerWaalsContact CG2-CD1 3.44Å; S206-I210 PolarHBondContact O-N 3.23Å; S206-I210 VanDerWaalsContact O-N 3.13Å; M207-I210 PolarHBondContact O-N 3.34Å; M207-I210 HydrophobicContact SD-CD1 4.27Å; R208-I210 PolarHBondContact O-N 2.88Å; I210-D212 VanDerWaalsContact C-N 3.32Å; I210-D212 PolarHBondContact O-N 3.31Å; I210-I213 PolarHBondContact O-N 3.43Å; I210-I214 HydrophobicContact CG2-CD1 3.86Å; I210-I214 HydrophobicContact CG2-CG1 4.4Å; I210-I214 VanDerWaalsContact O-CG1 3.31Å; I210-I214 WeakPolarHBondContact O-CG1 3.38Å; I210-I214 PolarHBondContact O-N 3.46Å; I210-I227 HydrophobicContact CG2-CD1 4.16Å; I210-Y255 HydrophobicContact CD1-CD1 4.13Å; I210-Y255 HydrophobicContact CD1-CE1 3.38Å; I210-Y255 HydrophobicContact CG2-CD1 3.98Å; I210-Y255 HydrophobicContact CG2-CE1 4.29Å
211A96Very high95.6Very high7 Ų729.2 Ų29.26%0.05817%0.167CC..Hα-helixtrans-59.9-41.7178.100000112.2M207 R208 I214 A215 A262M207-A211 PolarHBondContact O-N 2.87Å; M207-A211 VanDerWaalsContact O-N 3.1Å; R208-A211 PolarHBondContact O-N 3Å; R208-A211 VanDerWaalsContact O-N 3.12Å; A211-I214 PolarHBondContact O-N 2.83Å; A211-A215 WeakPolarHBondContact O-CB 3.24Å; A211-A215 PolarHBondContact O-N 3.11Å; A211-A262 HydrophobicContact CB-CB 4Å
212D97.1Very high95.5Very high22 Ų2232 Ų3212%0.11819%0.186CC..Hα-helixtrans-65.2-39.8177.3-81.67.1000112.4R208 I209 I210 A215 W216 N513 L514R208-D212 IonicContact NE-OD2 3.74Å; R208-D212 PolarHBondContact O-N 3.24Å; I209-D212 PolarHBondContact O-N 2.95Å; I210-D212 VanDerWaalsContact C-N 3.32Å; I210-D212 PolarHBondContact O-N 3.31Å; D212-A215 PolarHBondContact O-N 3.11Å; D212-W216 WeakPolarHBondContact O-CB 3.37Å; D212-W216 PolarHBondContact O-N 2.8Å; D212-N513 PolarHBondContact O-ND2 3.49Å; D212-L514 HydrophobicContact CB-CB 4.48Å; D212-L514 VanDerWaalsContact OD2-CG 3.26Å; D212-L514 WeakPolarHBondContact OD2-CG 3.41Å; D212-L514 PolarHBondContact OD2-N 3.01Å
213I98.1Very high95.6Very high0 Ų037.2 Ų37.20%020%0.201CC..Hα-helixtrans-63.8-48.1174.7-71.2166000110.3V160 L161 L164 N187 I209 I210 A215 W216 C217 L515V160-I213 HydrophobicContact CB-CD1 4.31Å; V160-I213 HydrophobicContact CG1-CD1 3.64Å; V160-I213 HydrophobicContact CG2-CD1 3.73Å; L161-I213 HydrophobicContact CD2-CD1 4.18Å; L161-I213 HydrophobicContact CD2-CG1 4.06Å; L164-I213 HydrophobicContact CD2-CG1 4.49Å; L164-I213 HydrophobicContact CD2-CG2 3.89Å; N187-I213 WeakPolarHBondContact OD1-CD1 3.42Å; I209-I213 HydrophobicContact CG2-CD1 3.84Å; I209-I213 WeakPolarHBondContact O-CG1 3.45Å; I209-I213 PolarHBondContact O-N 2.74Å; I210-I213 PolarHBondContact O-N 3.43Å; I213-A215 VanDerWaalsContact C-N 3.34Å; I213-A215 PolarHBondContact O-N 2.7Å; I213-W216 PolarHBondContact O-N 2.75Å; I213-C217 VanDerWaalsContact O-CB 3.27Å; I213-C217 WeakPolarHBondContact O-CB 3.36Å; I213-C217 PolarHBondContact O-N 2.82Å; I213-C217 PolarHBondContact O-SG 2.98Å; I213-C217 VanDerWaalsContact O-SG 3.4Å; I213-L515 HydrophobicContact CG1-CB 4.39Å; I213-L515 HydrophobicContact CG1-CD2 4.31Å
214I96.8Very high95.8Very high1 Ų136.6 Ų36.61%0.00520%0.198CC..Hα-helixtrans-58.9-48.5178.1-65.3172000109.7I210 A211 W216 C217 S218 A259 L264 F269I210-I214 HydrophobicContact CG2-CD1 3.86Å; I210-I214 HydrophobicContact CG2-CG1 4.4Å; I210-I214 VanDerWaalsContact O-CG1 3.31Å; I210-I214 WeakPolarHBondContact O-CG1 3.38Å; I210-I214 PolarHBondContact O-N 3.46Å; A211-I214 PolarHBondContact O-N 2.83Å; I214-W216 PolarHBondContact O-N 3.06Å; I214-C217 PolarHBondContact O-N 3.04Å; I214-S218 WeakPolarHBondContact O-CB 3.43Å; I214-S218 PolarHBondContact O-N 3.38Å; I214-S218 PolarHBondContact O-OG 3.04Å; I214-A259 HydrophobicContact CD1-CB 4.36Å; I214-L264 HydrophobicContact CB-CD1 4.27Å; I214-L264 HydrophobicContact CG2-CD1 3.59Å; I214-F269 HydrophobicContact CG2-CB 3.48Å; I214-F269 VanDerWaalsContact CG2-CB 3.48Å; I214-F269 HydrophobicContact CG2-CD2 4.09Å; I214-F269 HydrophobicContact CG2-CG 3.88Å
215A95.3Very high96.1Very high36 Ų3629.1 Ų29.130%0.29817%0.166SC..Hα-helixtrans-60-46.3-179.400000112.5A211 D212 I213 L264A211-A215 WeakPolarHBondContact O-CB 3.24Å; A211-A215 PolarHBondContact O-N 3.11Å; D212-A215 PolarHBondContact O-N 3.11Å; I213-A215 VanDerWaalsContact C-N 3.34Å; I213-A215 PolarHBondContact O-N 2.7Å; A215-L264 HydrophobicContact CB-CD1 4.13Å; A215-L264 HydrophobicContact CB-CD2 4.16Å; A215-L264 HydrophobicContact CB-CG 4.49Å
216W96.8Very high96.2Very high39 Ų3928.3 Ų28.315%0.14816%0.161CC..Hα-helixtrans-68.4-45-179.5-169.396.4000112I168 P178 D212 I213 I214 G219 N220 M221 L515I168-W216 HydrophobicContact CD1-CH2 3.92Å; I168-W216 HydrophobicContact CD1-CZ3 3.69Å; I168-W216 HydrophobicContact CG2-CH2 4.47Å; P178-W216 HydrophobicContact CB-CH2 4.33Å; P178-W216 HydrophobicContact CG-CH2 4.41Å; D212-W216 WeakPolarHBondContact O-CB 3.37Å; D212-W216 PolarHBondContact O-N 2.8Å; I213-W216 PolarHBondContact O-N 2.75Å; I214-W216 PolarHBondContact O-N 3.06Å; W216-G219 PolarHBondContact O-N 2.97Å; W216-N220 HydrophobicContact CD2-CB 4.14Å; W216-N220 HydrophobicContact CE3-CB 3.93Å; W216-N220 HydrophobicContact CH2-CB 3.7Å; W216-N220 HydrophobicContact CZ2-CB 3.91Å; W216-N220 HydrophobicContact CZ3-CB 3.72Å; W216-N220 WeakPolarHBondContact O-CB 3.48Å; W216-N220 PolarHBondContact O-N 3.21Å; W216-N220 PolarHBondContact O-ND2 2.99Å; W216-M221 HydrophobicContact CE3-SD 4.42Å; W216-M221 HydrophobicContact CZ3-CG 3.78Å; W216-M221 HydrophobicContact CZ3-SD 3.67Å; W216-L515 HydrophobicContact CB-CB 4.35Å; W216-L515 HydrophobicContact CB-CD2 4.06Å; W216-L515 HydrophobicContact CD2-CD2 3.85Å; W216-L515 HydrophobicContact CD2-CG 4.26Å; W216-L515 HydrophobicContact CE3-CD2 3.53Å; W216-L515 HydrophobicContact CE3-CG 4.31Å; W216-L515 HydrophobicContact CG-CB 4.39Å; W216-L515 HydrophobicContact CG-CD2 4.08Å; W216-L515 HydrophobicContact CG-CG 4.37Å; W216-L515 HydrophobicContact CZ3-CD2 4.27Å
217C97Very high96.3Very high1 Ų128.1 Ų28.11%0.00716%0.159CC..Hα-helixtrans-68.9-35.7-179.7-72.30000112.8I213 I214 G219 N220 M221 T226I213-C217 VanDerWaalsContact O-CB 3.27Å; I213-C217 WeakPolarHBondContact O-CB 3.36Å; I213-C217 PolarHBondContact O-N 2.82Å; I213-C217 PolarHBondContact O-SG 2.98Å; I213-C217 VanDerWaalsContact O-SG 3.4Å; I214-C217 PolarHBondContact O-N 3.04Å; C217-G219 PolarHBondContact O-N 3.33Å; C217-N220 PolarHBondContact O-N 3.13Å; C217-M221 HydrophobicContact CB-CB 4.21Å; C217-M221 CarbonylContact O-C 3.6Å; C217-M221 WeakPolarHBondContact O-CA 3.4Å; C217-M221 PolarHBondContact O-N 3.07Å; C217-T226 HydrophobicContact CB-CG2 3.42Å; C217-T226 VanDerWaalsContact CB-CG2 3.42Å
218S92.3Very high96.5Very high35 Ų3527.4 Ų27.425%0.24516%0.157CC..Hα-helixtrans-58.3-32.6174.5-80.70000112.2I214 D268I214-S218 WeakPolarHBondContact O-CB 3.43Å; I214-S218 PolarHBondContact O-N 3.38Å; I214-S218 PolarHBondContact O-OG 3.04Å; S218-D268 PolarHBondContact OG-O 2.89Å
219G92.7Very high96.6Very high61 Ų6125.2 Ų25.263%0.62915%0.149SC*.Hα-helixtrans-86.1-35.6175.600000115.3W216 C217W216-G219 PolarHBondContact O-N 2.97Å; C217-G219 PolarHBondContact O-N 3.33Å
220N97Very high96.7Very high76 Ų7625 Ų2541%0.40615%0.148SC..Hα-helixtrans-114.6-23.9-166.9-61.6-82.9000114.7P178 D179 W216 C217 P222P178-N220 CarbonylContact C-O 3.57Å; D179-N220 WeakPolarHBondContact CA-O 3.45Å; D179-N220 PolarHBondContact N-O 3.07Å; W216-N220 HydrophobicContact CD2-CB 4.14Å; W216-N220 HydrophobicContact CE3-CB 3.93Å; W216-N220 HydrophobicContact CH2-CB 3.7Å; W216-N220 HydrophobicContact CZ2-CB 3.91Å; W216-N220 HydrophobicContact CZ3-CB 3.72Å; W216-N220 WeakPolarHBondContact O-CB 3.48Å; W216-N220 PolarHBondContact O-N 3.21Å; W216-N220 PolarHBondContact O-ND2 2.99Å; C217-N220 PolarHBondContact O-N 3.13Å; N220-P222 VanDerWaalsContact C-CD 3.45Å
221M97.4Very high96.7Very high1 Ų124.9 Ų24.91%0.00515%0.147CC..  trans-129.358.2-178-66.3176.773.500111.4Y167 I168 P178 L181 W216 C217 R223 F224Y167-M221 HydrophobicContact CE1-CE 4.19Å; I168-M221 HydrophobicContact CD1-SD 3.92Å; I168-M221 HydrophobicContact CG1-CE 4.49Å; I168-M221 HydrophobicContact CG1-SD 3.97Å; P178-M221 HydrophobicContact CB-CG 3.73Å; L181-M221 HydrophobicContact CB-CE 3.87Å; L181-M221 HydrophobicContact CD1-CE 3.89Å; W216-M221 HydrophobicContact CE3-SD 4.42Å; W216-M221 HydrophobicContact CZ3-CG 3.78Å; W216-M221 HydrophobicContact CZ3-SD 3.67Å; C217-M221 HydrophobicContact CB-CB 4.21Å; C217-M221 CarbonylContact O-C 3.6Å; C217-M221 WeakPolarHBondContact O-CA 3.4Å; C217-M221 PolarHBondContact O-N 3.07Å; M221-R223 PolarHBondContact O-N 3.08Å; M221-F224 HydrophobicContact CB-CB 3.89Å; M221-F224 HydrophobicContact CE-CB 3.8Å; M221-F224 HydrophobicContact CE-CD1 3.95Å; M221-F224 HydrophobicContact CE-CD2 3.48Å; M221-F224 VanDerWaalsContact CE-CD2 3.48Å; M221-F224 HydrophobicContact CE-CE1 4.35Å; M221-F224 HydrophobicContact CE-CE2 3.96Å; M221-F224 HydrophobicContact CE-CG 3.48Å; M221-F224 VanDerWaalsContact CE-CG 3.48Å; M221-F224 HydrophobicContact CE-CZ 4.38Å; M221-F224 WeakPolarHBondContact O-CB 3.28Å; M221-F224 PolarHBondContact O-N 3.29Å
222P94.9Very high96.8Very high63 Ų6325.6 Ų25.641%0.40915%0.148SC..THydrogen-bonded Turntrans-66-2.1-170.528.8-38.9000114.7N220 R272N220-P222 VanDerWaalsContact C-CD 3.45Å; P222-R272 PolarHBondContact O-NE 2.57Å; P222-R272 PolarHBondContact O-NH2 3.27Å
223R95.4Very high96.9Very high140 Ų14025.5 Ų25.553%0.52815%0.147SC..THydrogen-bonded Turntrans-106.3-5.4176.1-59.5-179.4-177.4-173.51.5113.6D179 T182 M221D179-R223 WeakPolarHBondContact O-CD 3.27Å; T182-R223 HydrophobicContact CG2-CB 4.05Å; M221-R223 PolarHBondContact O-N 3.08Å
224F97.5Very high96.9Very high1 Ų125.5 Ų25.50%0.00415%0.147CC..EExtended strand (participates in β ladder)trans-92.9136.6-176.3-161.5-99.4000110.4M154 L164 Y167 I185 M221 R272M154-F224 HydrophobicContact CE-CE2 4.47Å; M154-F224 HydrophobicContact CE-CZ 3.89Å; L164-F224 HydrophobicContact CD1-CE1 4.08Å; L164-F224 HydrophobicContact CD1-CZ 4.13Å; Y167-F224 HydrophobicContact CD1-CE2 4.42Å; Y167-F224 HydrophobicContact CE1-CD2 4.39Å; Y167-F224 AromaticContact CE1-CE2 3.69Å; Y167-F224 HydrophobicContact CE1-CE2 3.69Å; Y167-F224 HydrophobicContact CE1-CZ 4.32Å; I185-F224 HydrophobicContact CB-CE1 3.77Å; I185-F224 HydrophobicContact CB-CZ 4.13Å; I185-F224 HydrophobicContact CG2-CE1 3.67Å; M221-F224 HydrophobicContact CB-CB 3.89Å; M221-F224 HydrophobicContact CE-CB 3.8Å; M221-F224 HydrophobicContact CE-CD1 3.95Å; M221-F224 HydrophobicContact CE-CD2 3.48Å; M221-F224 VanDerWaalsContact CE-CD2 3.48Å; M221-F224 HydrophobicContact CE-CE1 4.35Å; M221-F224 HydrophobicContact CE-CE2 3.96Å; M221-F224 HydrophobicContact CE-CG 3.48Å; M221-F224 VanDerWaalsContact CE-CG 3.48Å; M221-F224 HydrophobicContact CE-CZ 4.38Å; M221-F224 WeakPolarHBondContact O-CB 3.28Å; M221-F224 PolarHBondContact O-N 3.29Å; F224-R272 WeakPolarHBondContact O-CD 3.38Å
225N97Very high96.9Very high27 Ų2726.1 Ų26.114%0.14415%0.153CC..EExtended strand (participates in β ladder)trans-82.3118.7171.9-55.2-55000108.2G183 T184 I185 I227 R272 R315G183-N225 PolarHBondContact O-N 2.78Å; G183-N225 PolarHBondContact O-ND2 3.19Å; T184-N225 WeakPolarHBondContact CA-O 3.49Å; T184-N225 HydrophobicContact CG2-CB 3.94Å; T184-N225 WeakPolarHBondContact OG1-CB 3.23Å; T184-N225 PolarHBondContact OG1-ND2 3.06Å; I185-N225 PolarHBondContact N-O 2.9Å; N225-I227 VanDerWaalsContact C-N 3.32Å; N225-I227 PolarHBondContact O-N 3.11Å; N225-R272 VanDerWaalsContact CA-O 3.27Å; N225-R272 WeakPolarHBondContact CA-O 3.31Å; N225-R272 WeakPolarHBondContact CB-O 3.42Å; N225-R315 PolarHBondContact OD1-NH1 3.18Å; N225-R315 PolarHBondContact OD1-NH2 2.98Å; N225-R315 VanDerWaalsContact OD1-NH2 3.13Å
226T97.5Very high97.1Very high2 Ų226.1 Ų26.11%0.01215%0.148CC..  trans-81.4-12.9-167.454.90000114.1I185 N187 C217 R272I185-T226 VanDerWaalsContact CG2-O 3.26Å; I185-T226 WeakPolarHBondContact CG2-O 3.36Å; N187-T226 PolarHBondContact ND2-O 3.18Å; C217-T226 HydrophobicContact CB-CG2 3.42Å; C217-T226 VanDerWaalsContact CB-CG2 3.42Å; T226-R272 PolarHBondContact N-O 3.47Å
227I98.5Very high97.1Very high0 Ų025 Ų250%015%0.146CC..EExtended strand (participates in β ladder)trans-159.1147.4179.4-170.9167.3000109.7I185 Q186 N187 D188 I210 N225 I229 Y255 L273 S274I185-I227 CarbonylContact O-C 3.57Å; I185-I227 WeakPolarHBondContact O-CA 3.3Å; Q186-I227 WeakPolarHBondContact O-CG1 3.46Å; N187-I227 HydrophobicContact CB-CG1 4.43Å; N187-I227 WeakPolarHBondContact O-CD1 3.48Å; N187-I227 WeakPolarHBondContact O-CG1 3.32Å; D188-I227 HydrophobicContact CB-CD1 4.5Å; D188-I227 HydrophobicContact CB-CG1 4.34Å; I210-I227 HydrophobicContact CG2-CD1 4.16Å; N225-I227 VanDerWaalsContact C-N 3.32Å; N225-I227 PolarHBondContact O-N 3.11Å; I227-I229 HydrophobicContact CD1-CG1 4.28Å; I227-I229 HydrophobicContact CG1-CG1 4.17Å; I227-I229 HydrophobicContact CG2-CG1 4.22Å; I227-Y255 HydrophobicContact CD1-CD1 3.89Å; I227-Y255 HydrophobicContact CD1-CD2 3.49Å; I227-Y255 VanDerWaalsContact CD1-CD2 3.49Å; I227-Y255 HydrophobicContact CD1-CE1 3.97Å; I227-Y255 HydrophobicContact CD1-CE2 3.54Å; I227-Y255 HydrophobicContact CD1-CG 3.67Å; I227-L273 HydrophobicContact CG2-CD2 3.25Å; I227-L273 HydrophobicContact CG2-CG 4.48Å; I227-S274 PolarHBondContact O-N 2.81Å; I227-S274 VanDerWaalsContact O-N 3.16Å; I227-S274 PolarHBondContact O-OG 3.25Å
228S98.4Very high97.1Very high10 Ų1025.5 Ų25.57%0.0715%0.152CC..EExtended strand (participates in β ladder)trans-119.794.8170.4-177.30000108.5I185 Q186 S230 S274 F276I185-S228 PolarHBondContact O-N 3.32Å; Q186-S228 PolarHBondContact O-N 3.35Å; S228-S230 PolarHBondContact O-N 3.23Å; S228-S230 PolarHBondContact O-OG 2.89Å; S228-S274 CarbonylContact C-O 3.52Å; S228-S274 WeakPolarHBondContact CA-O 3.34Å; S228-F276 WeakPolarHBondContact OG-CB 3.37Å
229I98.6Very high97.4Very high0 Ų024.1 Ų24.10%014%0.142CC..EExtended strand (participates in β ladder)trans-71.1114.5-176.2-52.1159.7000108.7D188 I227 T248 D251 Y255 L273 S274 F275 F276 W297D188-I229 WeakPolarHBondContact OD2-CA 3.26Å; I227-I229 HydrophobicContact CD1-CG1 4.28Å; I227-I229 HydrophobicContact CG1-CG1 4.17Å; I227-I229 HydrophobicContact CG2-CG1 4.22Å; I229-T248 HydrophobicContact CG2-CG2 3.82Å; I229-T248 WeakPolarHBondContact CG2-O 3.37Å; I229-T248 WeakPolarHBondContact O-CG2 3.41Å; I229-D251 HydrophobicContact CG2-CB 4.1Å; I229-Y255 HydrophobicContact CG1-CD2 4.06Å; I229-Y255 HydrophobicContact CG1-CE2 4.46Å; I229-Y255 HydrophobicContact CG2-CD2 4.46Å; I229-Y255 HydrophobicContact CG2-CE2 4.44Å; I229-L273 HydrophobicContact CD1-CB 4.38Å; I229-S274 PolarHBondContact N-O 2.89Å; I229-F275 HydrophobicContact CB-CD1 3.84Å; I229-F275 HydrophobicContact CB-CE1 3.82Å; I229-F275 HydrophobicContact CB-CG 4.4Å; I229-F275 HydrophobicContact CB-CZ 4.39Å; I229-F275 HydrophobicContact CD1-CE1 3.9Å; I229-F275 HydrophobicContact CD1-CE2 4.01Å; I229-F275 HydrophobicContact CD1-CZ 3.6Å; I229-F275 HydrophobicContact CG1-CE1 4.48Å; I229-F275 HydrophobicContact CG2-CD1 4.19Å; I229-F275 HydrophobicContact CG2-CE1 3.89Å; I229-F275 CarbonylContact O-C 3.53Å; I229-F275 WeakPolarHBondContact O-CA 3.47Å; I229-F276 PolarHBondContact O-N 3.18Å; I229-W297 HydrophobicContact CD1-CH2 4.42Å
230S98.5Very high97.6Very high0 Ų022.4 Ų22.40%012%0.119CC..EExtended strand (participates in β ladder)trans-119.1109.4-151-67.50000114.2D188 S228 F276D188-S230 WeakPolarHBondContact OD2-CB 3.36Å; D188-S230 PolarHBondContact OD2-N 3.08Å; S228-S230 PolarHBondContact O-N 3.23Å; S228-S230 PolarHBondContact O-OG 2.89Å; S230-F276 CarbonylContact C-O 3.57Å; S230-F276 WeakPolarHBondContact CA-O 3.5Å
231G98.4Very high97.7Very high0 Ų019.2 Ų19.20%010%0.102CC..  trans-86.9-18.6167.800000115.1H233 M234 G235 Q244 T248 F276G231-H233 PolarHBondContact O-N 3.1Å; G231-M234 WeakPolarHBondContact O-CB 3.29Å; G231-M234 PolarHBondContact O-N 3.34Å; G231-G235 PolarHBondContact O-N 3.46Å; G231-Q244 PolarHBondContact O-OE1 3.37Å; G231-T248 WeakPolarHBondContact CA-OG1 3.46Å; G231-T248 PolarHBondContact N-OG1 3.36Å; G231-F276 PolarHBondContact N-O 3.2Å
232Y98.5Very high97.8Very high23 Ų2319.4 Ų19.49%0.0910%0.103CC..Hα-helixtrans-48.5-56.9-179.6169.5-102.4000112.4M234 G235 E236 F276 Q319Y232-M234 PolarHBondContact O-N 3.24Å; Y232-G235 WeakPolarHBondContact O-CA 3.27Å; Y232-G235 PolarHBondContact O-N 3.19Å; Y232-E236 HydrophobicContact CD1-CG 4.19Å; Y232-E236 HydrophobicContact CD2-CG 4.1Å; Y232-E236 HydrophobicContact CE1-CG 3.78Å; Y232-E236 HydrophobicContact CE2-CG 3.67Å; Y232-E236 HydrophobicContact CG-CG 4.34Å; Y232-E236 WeakPolarHBondContact O-CG 3.39Å; Y232-E236 PolarHBondContact O-N 3.43Å; Y232-F276 AromaticContact CD1-CE1 3.68Å; Y232-F276 HydrophobicContact CD1-CE1 3.68Å; Y232-F276 HydrophobicContact CD1-CE2 4.49Å; Y232-F276 AromaticContact CD1-CZ 3.53Å; Y232-F276 HydrophobicContact CD1-CZ 3.53Å; Y232-F276 HydrophobicContact CD2-CE2 4.18Å; Y232-F276 AromaticContact CD2-CZ 3.91Å; Y232-F276 HydrophobicContact CD2-CZ 3.91Å; Y232-F276 HydrophobicContact CE1-CZ 4.28Å; Y232-F276 AromaticContact CG-CE1 3.76Å; Y232-F276 HydrophobicContact CG-CE1 3.76Å; Y232-F276 AromaticContact CG-CE2 3.85Å; Y232-F276 HydrophobicContact CG-CE2 3.85Å; Y232-F276 AromaticContact CG-CZ 3.3Å; Y232-F276 HydrophobicContact CG-CZ 3.3Å; Y232-F276 PolarHBondContact N-O 3.33Å; Y232-F276 VanDerWaalsContact N-O 3.09Å; Y232-Q319 HydrophobicContact CD2-CB 3.81Å; Y232-Q319 HydrophobicContact CD2-CG 4.13Å; Y232-Q319 HydrophobicContact CE2-CB 3.79Å; Y232-Q319 HydrophobicContact CE2-CG 3.57Å; Y232-Q319 PolarHBondContact OH-NE2 2.64Å
233H97.9Very high97.9Very high20 Ų2017.1 Ų17.19%0.0939%0.087CC..Hα-helixtrans-64.1-30.1-177.2-41.986000112.8Q186 K191 C195 R196 G231 A237 F276Q186-H233 PolarHBondContact NE2-CE1 2.87Å; Q186-H233 VanDerWaalsContact NE2-CE1 3.32Å; K191-H233 HydrophobicContact CD-CB 4.24Å; K191-H233 VanDerWaalsContact CD-ND1 3.26Å; K191-H233 WeakPolarHBondContact CD-ND1 3.35Å; K191-H233 VanDerWaalsContact CE-CE1 3.46Å; K191-H233 WeakPolarHBondContact CE-CE1 3.49Å; K191-H233 WeakPolarHBondContact CE-ND1 2.89Å; C195-H233 PolarHBondContact SG-O 3.19Å; R196-H233 HydrophobicContact CB-CB 4.3Å; R196-H233 WeakPolarHBondContact CD-CD2 3.44Å; R196-H233 WeakPolarHBondContact CD-NE2 3.27Å; R196-H233 PolarHBondContact NE-CD2 2.9Å; R196-H233 PolarHBondContact NE-NE2 3.5Å; G231-H233 PolarHBondContact O-N 3.1Å; H233-A237 WeakPolarHBondContact O-CB 3.44Å; H233-A237 PolarHBondContact O-N 2.97Å; H233-F276 AromaticContact CE1-CD1 3.95Å; H233-F276 AromaticContact CE1-CE1 3.72Å
234M98.3Very high98.1Very high0 Ų011 Ų110%07%0.065CC..Hα-helixtrans-67.4-43.9173.8-55.4175.4-172.600109.8K191 L194 G231 Y232 A237 G238 A239 F247 D251 I435K191-M234 HydrophobicContact CB-CE 3.85Å; L194-M234 HydrophobicContact CD1-CE 4.05Å; G231-M234 WeakPolarHBondContact O-CB 3.29Å; G231-M234 PolarHBondContact O-N 3.34Å; Y232-M234 PolarHBondContact O-N 3.24Å; M234-A237 PolarHBondContact O-N 2.9Å; M234-G238 PolarHBondContact O-N 3.34Å; M234-A239 VanDerWaalsContact C-CB 3.43Å; M234-A239 HydrophobicContact CB-CB 3.92Å; M234-A239 WeakPolarHBondContact O-CB 3.5Å; M234-A239 PolarHBondContact O-N 3.15Å; M234-F247 HydrophobicContact CE-CB 4.04Å; M234-F247 HydrophobicContact SD-CB 3.4Å; M234-F247 WeakPolarHBondContact SD-CB 3.38Å; M234-F247 HydrophobicContact SD-CD2 4.29Å; M234-F247 HydrophobicContact SD-CG 4.34Å; M234-D251 WeakPolarHBondContact CE-OD2 3.47Å; M234-I435 HydrophobicContact CB-CD1 4.22Å; M234-I435 HydrophobicContact CG-CD1 4.46Å
235G97.8Very high98.2Very high13 Ų1311 Ų1113%0.1347%0.065CC..Hα-helixtrans-58.1-49.117300000112.6G231 Y232 A237 G238 A239G231-G235 PolarHBondContact O-N 3.46Å; Y232-G235 WeakPolarHBondContact O-CA 3.27Å; Y232-G235 PolarHBondContact O-N 3.19Å; G235-A237 PolarHBondContact O-N 3.15Å; G235-G238 PolarHBondContact O-N 3.19Å; G235-A239 WeakPolarHBondContact CA-O 3.35Å
236E98Very high98.2Very high37 Ų379.7 Ų9.717%0.1736%0.058CC..Hα-helixtrans-61.3-30.4177.7-62.9-58.1106.700112.7Y232 G238 S321 G322 W323 R599Y232-E236 HydrophobicContact CD1-CG 4.19Å; Y232-E236 HydrophobicContact CD2-CG 4.1Å; Y232-E236 HydrophobicContact CE1-CG 3.78Å; Y232-E236 HydrophobicContact CE2-CG 3.67Å; Y232-E236 HydrophobicContact CG-CG 4.34Å; Y232-E236 WeakPolarHBondContact O-CG 3.39Å; Y232-E236 PolarHBondContact O-N 3.43Å; E236-G238 VanDerWaalsContact C-N 3.35Å; E236-S321 VanDerWaalsContact OE1-CA 3.26Å; E236-S321 WeakPolarHBondContact OE1-CA 3.4Å; E236-S321 WeakPolarHBondContact OE1-CB 3.11Å; E236-S321 PolarHBondContact OE1-OG 2.94Å; E236-G322 PolarHBondContact OE1-N 3.38Å; E236-G322 VanDerWaalsContact OE2-CA 3.3Å; E236-G322 WeakPolarHBondContact OE2-CA 3.39Å; E236-G322 PolarHBondContact OE2-N 3.34Å; E236-W323 PolarHBondContact OE2-N 3.17Å; E236-R599 WeakPolarHBondContact O-CD 3.37Å; E236-R599 PolarHBondContact O-NH1 3.02Å
237A97.5Very high98.3Very high14 Ų149.6 Ų9.612%0.1166%0.057CC..Hα-helixtrans-78-16.2174.500000114.1C195 H233 M234 G235 I435 S439 R599C195-A237 HydrophobicContact CB-CB 3.55Å; H233-A237 WeakPolarHBondContact O-CB 3.44Å; H233-A237 PolarHBondContact O-N 2.97Å; M234-A237 PolarHBondContact O-N 2.9Å; G235-A237 PolarHBondContact O-N 3.15Å; A237-I435 HydrophobicContact CB-CG2 3.76Å; A237-S439 WeakPolarHBondContact O-CB 3.39Å; A237-S439 PolarHBondContact O-OG 2.88Å; A237-R599 WeakPolarHBondContact O-CD 3.29Å
238G97.1Very high98.3Very high12 Ų129.6 Ų9.612%0.1246%0.057CC..THydrogen-bonded Turntrans127.83.8175.800000115.3M234 G235 E236 N240 A438M234-G238 PolarHBondContact O-N 3.34Å; G235-G238 PolarHBondContact O-N 3.19Å; E236-G238 VanDerWaalsContact C-N 3.35Å; G238-N240 PolarHBondContact O-N 3.33Å; G238-A438 VanDerWaalsContact O-CB 3.26Å; G238-A438 WeakPolarHBondContact O-CB 3.42Å
239A98.2Very high98.3Very high6 Ų69.1 Ų9.15%0.055%0.054CC..  trans-66.1127.4176.500000111M234 G235 Q243 Q244 I435M234-A239 VanDerWaalsContact C-CB 3.43Å; M234-A239 HydrophobicContact CB-CB 3.92Å; M234-A239 WeakPolarHBondContact O-CB 3.5Å; M234-A239 PolarHBondContact O-N 3.15Å; G235-A239 WeakPolarHBondContact CA-O 3.35Å; A239-Q243 VanDerWaalsContact CA-OE1 3.29Å; A239-Q243 HydrophobicContact CB-CB 3.89Å; A239-Q244 HydrophobicContact CB-CG 4Å; A239-I435 HydrophobicContact CB-CD1 4.46Å; A239-I435 HydrophobicContact CB-CG1 4.02Å
240N97.9Very high98.3Very high26 Ų269.3 Ų9.314%0.1396%0.056CC..  trans-70.3174.8172.469.635.8000111.5A30 E31 G238 V242 Q243 Q244A30-N240 PolarHBondContact O-ND2 2.72Å; E31-N240 HydrophobicContact CG-CB 4.04Å; G238-N240 PolarHBondContact O-N 3.33Å; N240-V242 VanDerWaalsContact C-N 3.3Å; N240-V242 PolarHBondContact O-N 3.05Å; N240-V242 PolarHBondContact OD1-N 3.13Å; N240-V242 VanDerWaalsContact OD1-N 3.15Å; N240-Q243 PolarHBondContact O-N 3.2Å; N240-Q243 WeakPolarHBondContact OD1-CG 3.4Å; N240-Q243 PolarHBondContact OD1-N 3.3Å; N240-Q244 PolarHBondContact O-N 2.83Å
241C98.5Very high98.3Very high9 Ų99.3 Ų9.36%0.0616%0.056CC..Hα-helixtrans-61.6-36.1-174.1-66.10000113.3E31 V245 M285 M289E31-C241 HydrophobicContact CG-CB 4.19Å; E31-C241 PolarHBondContact OE1-N 3.2Å; C241-V245 WeakPolarHBondContact O-CG2 3.18Å; C241-V245 PolarHBondContact O-N 2.99Å; C241-M285 HydrophobicContact CB-CG 3.66Å; C241-M285 HydrophobicContact CB-SD 4.4Å; C241-M285 WeakPolarHBondContact SG-CG 3.27Å; C241-M289 HydrophobicContact CB-CB 4.12Å; C241-M289 HydrophobicContact CB-CG 4Å; C241-M289 HydrophobicContact CB-SD 3.72Å
242V98.7Very high98.3Very high4 Ų49.3 Ų9.32%0.0246%0.056CC..Hα-helixtrans-66.9-44.4177.3166.90000111.1E31 I33 N240 V245 A246 I405 Q408 A409 I412E31-V242 HydrophobicContact CB-CB 4.36Å; E31-V242 HydrophobicContact CB-CG2 3.78Å; E31-V242 HydrophobicContact CG-CB 4.26Å; E31-V242 HydrophobicContact CG-CG2 3.82Å; I33-V242 HydrophobicContact CD1-CG2 4.3Å; N240-V242 VanDerWaalsContact C-N 3.3Å; N240-V242 PolarHBondContact O-N 3.05Å; N240-V242 PolarHBondContact OD1-N 3.13Å; N240-V242 VanDerWaalsContact OD1-N 3.15Å; V242-V245 PolarHBondContact O-N 3.24Å; V242-A246 WeakPolarHBondContact O-CB 3.19Å; V242-A246 PolarHBondContact O-N 3.49Å; V242-I405 HydrophobicContact CG2-CB 4.4Å; V242-I405 HydrophobicContact CG2-CG1 4.15Å; V242-I405 HydrophobicContact CG2-CG2 4.18Å; V242-Q408 HydrophobicContact CG1-CB 3.62Å; V242-Q408 HydrophobicContact CG2-CB 4.13Å; V242-A409 HydrophobicContact CG1-CB 4.37Å; V242-I412 HydrophobicContact CG1-CD1 3.81Å
243Q98.6Very high98.3Very high16 Ų169 Ų98%0.0756%0.055CC..Hα-helixtrans-64.8-43.3177.2-73.2172.8-29.400111.7A239 N240 V245 A246 F247 I412 M434A239-Q243 VanDerWaalsContact CA-OE1 3.29Å; A239-Q243 HydrophobicContact CB-CB 3.89Å; N240-Q243 PolarHBondContact O-N 3.2Å; N240-Q243 WeakPolarHBondContact OD1-CG 3.4Å; N240-Q243 PolarHBondContact OD1-N 3.3Å; Q243-V245 VanDerWaalsContact C-N 3.32Å; Q243-V245 PolarHBondContact O-N 2.99Å; Q243-A246 PolarHBondContact O-N 3.06Å; Q243-F247 HydrophobicContact CB-CD2 4.06Å; Q243-F247 HydrophobicContact CB-CE2 3.68Å; Q243-F247 HydrophobicContact CB-CZ 4.3Å; Q243-F247 HydrophobicContact CG-CE2 4.01Å; Q243-F247 HydrophobicContact CG-CZ 4.23Å; Q243-F247 WeakPolarHBondContact O-CB 3.42Å; Q243-F247 VanDerWaalsContact O-CD2 3.27Å; Q243-F247 WeakPolarHBondContact O-CD2 3.46Å; Q243-F247 VanDerWaalsContact O-CG 3.29Å; Q243-F247 WeakPolarHBondContact O-CG 3.21Å; Q243-F247 PolarHBondContact O-N 3.34Å; Q243-I412 HydrophobicContact CG-CD1 4.15Å; Q243-M434 PolarHBondContact NE2-O 2.8Å; Q243-M434 VanDerWaalsContact NE2-O 3.15Å
244Q98.6Very high98.2Very high11 Ų119.8 Ų9.85%0.0516%0.059CC..Hα-helixtrans-55.4-47.8174.9-76.9-171.567.200111.1G231 A239 N240 T248 G278 M289G231-Q244 PolarHBondContact O-OE1 3.37Å; A239-Q244 HydrophobicContact CB-CG 4Å; N240-Q244 PolarHBondContact O-N 2.83Å; Q244-T248 WeakPolarHBondContact O-CB 3.49Å; Q244-T248 PolarHBondContact O-N 3.16Å; Q244-T248 VanDerWaalsContact O-N 3.15Å; Q244-T248 PolarHBondContact O-OG1 3.16Å; Q244-G278 PolarHBondContact OE1-O 3.2Å; Q244-M289 HydrophobicContact CB-SD 4.12Å
245V98.8Very high98.2Very high0 Ų09.8 Ų9.80%06%0.059CC..Hα-helixtrans-62.1-51.8177.11750000111C241 V242 Q243 L249 M289 A293 L296 I405 A409C241-V245 WeakPolarHBondContact O-CG2 3.18Å; C241-V245 PolarHBondContact O-N 2.99Å; V242-V245 PolarHBondContact O-N 3.24Å; Q243-V245 VanDerWaalsContact C-N 3.32Å; Q243-V245 PolarHBondContact O-N 2.99Å; V245-L249 HydrophobicContact CG1-CD1 3.79Å; V245-L249 HydrophobicContact CG1-CG 4.3Å; V245-L249 WeakPolarHBondContact O-CB 3.26Å; V245-L249 VanDerWaalsContact O-CG 3.23Å; V245-L249 WeakPolarHBondContact O-CG 3.39Å; V245-L249 PolarHBondContact O-N 3.07Å; V245-M289 HydrophobicContact CG2-CB 4.47Å; V245-M289 HydrophobicContact CG2-CG 3.33Å; V245-M289 HydrophobicContact CG2-SD 4.36Å; V245-A293 HydrophobicContact CG1-CB 4.34Å; V245-A293 HydrophobicContact CG2-CB 4.26Å; V245-L296 HydrophobicContact CG1-CD1 3.77Å; V245-I405 HydrophobicContact CG2-CG2 4.33Å; V245-A409 HydrophobicContact CB-CB 4.14Å; V245-A409 HydrophobicContact CG1-CB 3.83Å
246A98.7Very high98.2Very high0 Ų09.2 Ų9.20%05%0.053CC..Hα-helixtrans-61.2-51.9-174.200000112.9V242 Q243 A250 A409 I412 I413V242-A246 WeakPolarHBondContact O-CB 3.19Å; V242-A246 PolarHBondContact O-N 3.49Å; Q243-A246 PolarHBondContact O-N 3.06Å; A246-A250 VanDerWaalsContact O-CB 3.3Å; A246-A250 WeakPolarHBondContact O-CB 3.37Å; A246-A250 PolarHBondContact O-N 3.3Å; A246-A409 HydrophobicContact CB-CB 4.16Å; A246-I412 HydrophobicContact CB-CB 3.56Å; A246-I412 HydrophobicContact CB-CD1 4.25Å; A246-I412 HydrophobicContact CB-CG1 4.48Å; A246-I412 HydrophobicContact CB-CG2 3.5Å; A246-I412 VanDerWaalsContact CB-CG2 3.5Å; A246-I413 HydrophobicContact CB-CG1 4.06Å
247F98.7Very high98.1Very high0 Ų010.7 Ų10.70%06%0.058CC..Hα-helixtrans-66.9-41.5-177.4-60.3-29.3000111.9M234 Q243 L249 A250 D251 I412 I416 M422 P431 M434 I435M234-F247 HydrophobicContact CE-CB 4.04Å; M234-F247 HydrophobicContact SD-CB 3.4Å; M234-F247 WeakPolarHBondContact SD-CB 3.38Å; M234-F247 HydrophobicContact SD-CD2 4.29Å; M234-F247 HydrophobicContact SD-CG 4.34Å; Q243-F247 HydrophobicContact CB-CD2 4.06Å; Q243-F247 HydrophobicContact CB-CE2 3.68Å; Q243-F247 HydrophobicContact CB-CZ 4.3Å; Q243-F247 HydrophobicContact CG-CE2 4.01Å; Q243-F247 HydrophobicContact CG-CZ 4.23Å; Q243-F247 WeakPolarHBondContact O-CB 3.42Å; Q243-F247 VanDerWaalsContact O-CD2 3.27Å; Q243-F247 WeakPolarHBondContact O-CD2 3.46Å; Q243-F247 VanDerWaalsContact O-CG 3.29Å; Q243-F247 WeakPolarHBondContact O-CG 3.21Å; Q243-F247 PolarHBondContact O-N 3.34Å; F247-L249 PolarHBondContact O-N 3.04Å; F247-A250 PolarHBondContact O-N 3.15Å; F247-D251 PolarHBondContact O-N 3.4Å; F247-I412 HydrophobicContact CD1-CG2 4.1Å; F247-I412 HydrophobicContact CE1-CG2 3.56Å; F247-I412 HydrophobicContact CZ-CG2 4.35Å; F247-I416 HydrophobicContact CD1-CD1 3.65Å; F247-I416 HydrophobicContact CE1-CD1 3.99Å; F247-M422 HydrophobicContact CB-CE 3.83Å; F247-M422 HydrophobicContact CD1-CE 4.26Å; F247-M422 HydrophobicContact CG-CE 4.28Å; F247-P431 HydrophobicContact CD1-CB 3.99Å; F247-P431 HydrophobicContact CD2-CB 4.46Å; F247-P431 HydrophobicContact CE1-CB 3.79Å; F247-P431 HydrophobicContact CE1-CG 4.43Å; F247-P431 HydrophobicContact CE2-CB 4.28Å; F247-P431 HydrophobicContact CG-CB 4.34Å; F247-P431 HydrophobicContact CZ-CB 3.95Å; F247-M434 HydrophobicContact CE1-SD 4.18Å; F247-M434 HydrophobicContact CZ-CB 4Å; F247-M434 HydrophobicContact CZ-CE 4.13Å; F247-M434 HydrophobicContact CZ-SD 3.87Å; F247-I435 HydrophobicContact CD2-CD1 4.07Å; F247-I435 HydrophobicContact CD2-CG1 4.18Å; F247-I435 HydrophobicContact CE2-CD1 4.08Å; F247-I435 HydrophobicContact CE2-CG1 3.72Å
248T98.8Very high97.9Very high0 Ų011.1 Ų11.10%06%0.062CC..Hα-helixtrans-66.1-41.4179.6-55.60000111.9I229 G231 Q244 G252 F275 F277I229-T248 HydrophobicContact CG2-CG2 3.82Å; I229-T248 WeakPolarHBondContact CG2-O 3.37Å; I229-T248 WeakPolarHBondContact O-CG2 3.41Å; G231-T248 WeakPolarHBondContact CA-OG1 3.46Å; G231-T248 PolarHBondContact N-OG1 3.36Å; Q244-T248 WeakPolarHBondContact O-CB 3.49Å; Q244-T248 PolarHBondContact O-N 3.16Å; Q244-T248 VanDerWaalsContact O-N 3.15Å; Q244-T248 PolarHBondContact O-OG1 3.16Å; T248-G252 PolarHBondContact O-N 3.43Å; T248-F275 HydrophobicContact CG2-CD1 3.79Å; T248-F275 HydrophobicContact CG2-CE1 4.16Å; T248-F277 HydrophobicContact CG2-CE1 4Å; T248-F277 HydrophobicContact CG2-CZ 4.01Å
249L98.7Very high97.8Very high1 Ų110.5 Ų10.51%0.0056%0.056CC..Hα-helixtrans-71-36.2177.2-64-174.4000111.6V245 F247 G252 I253 F275 L296 W297 L314 I413V245-L249 HydrophobicContact CG1-CD1 3.79Å; V245-L249 HydrophobicContact CG1-CG 4.3Å; V245-L249 WeakPolarHBondContact O-CB 3.26Å; V245-L249 VanDerWaalsContact O-CG 3.23Å; V245-L249 WeakPolarHBondContact O-CG 3.39Å; V245-L249 PolarHBondContact O-N 3.07Å; F247-L249 PolarHBondContact O-N 3.04Å; L249-G252 PolarHBondContact O-N 3.25Å; L249-I253 VanDerWaalsContact O-CG1 3.31Å; L249-I253 WeakPolarHBondContact O-CG1 3.44Å; L249-I253 PolarHBondContact O-N 3.39Å; L249-F275 HydrophobicContact CD2-CD1 4.47Å; L249-F275 HydrophobicContact CD2-CE1 3.74Å; L249-F275 HydrophobicContact CD2-CZ 4.2Å; L249-L296 HydrophobicContact CD1-CB 3.34Å; L249-L296 HydrophobicContact CD1-CD1 4.11Å; L249-L296 HydrophobicContact CD1-CG 4.39Å; L249-W297 HydrophobicContact CD2-CB 3.98Å; L249-W297 HydrophobicContact CD2-CD2 4.46Å; L249-W297 HydrophobicContact CD2-CE3 3.94Å; L249-L314 HydrophobicContact CD2-CD1 3.93Å; L249-I413 HydrophobicContact CB-CD1 4.16Å; L249-I413 HydrophobicContact CD1-CD1 4.42Å
250A98.5Very high97.7Very high4 Ų413.3 Ų13.33%0.0337%0.07CC..Hα-helixtrans-63-41.7173.900000112.2A246 F247 G252 I253 E254 I416 M422A246-A250 VanDerWaalsContact O-CB 3.3Å; A246-A250 WeakPolarHBondContact O-CB 3.37Å; A246-A250 PolarHBondContact O-N 3.3Å; F247-A250 PolarHBondContact O-N 3.15Å; A250-G252 VanDerWaalsContact C-N 3.34Å; A250-I253 PolarHBondContact O-N 2.92Å; A250-E254 PolarHBondContact O-N 3.42Å; A250-I416 HydrophobicContact CB-CD1 3.87Å; A250-I416 HydrophobicContact CB-CG2 4.06Å; A250-M422 HydrophobicContact CB-CB 4.19Å; A250-M422 HydrophobicContact CB-CG 4.18Å; A250-M422 HydrophobicContact CB-SD 4.26Å
251D98.3Very high97.4Very high0 Ų017.2 Ų17.20%010%0.099CC..Hα-helixtrans-57.9-47.7170.4-78.3-14.9000110.7L190 I229 M234 F247 I253 E254 Y255 M422L190-D251 HydrophobicContact CB-CB 4.49Å; L190-D251 VanDerWaalsContact CB-OD1 3.26Å; L190-D251 WeakPolarHBondContact CB-OD1 3.34Å; L190-D251 HydrophobicContact CD1-CB 4.11Å; L190-D251 WeakPolarHBondContact CD1-OD1 3.47Å; I229-D251 HydrophobicContact CG2-CB 4.1Å; M234-D251 WeakPolarHBondContact CE-OD2 3.47Å; F247-D251 PolarHBondContact O-N 3.4Å; D251-I253 VanDerWaalsContact C-N 3.33Å; D251-I253 PolarHBondContact O-N 3.24Å; D251-E254 WeakPolarHBondContact O-CB 3.38Å; D251-E254 PolarHBondContact O-N 3.24Å; D251-E254 VanDerWaalsContact O-N 3.07Å; D251-Y255 HydrophobicContact CB-CD2 4.44Å; D251-Y255 HydrophobicContact CB-CE2 4Å; D251-Y255 WeakPolarHBondContact O-CD2 3.11Å; D251-Y255 PolarHBondContact O-N 3.35Å; D251-M422 WeakPolarHBondContact OD1-CE 3.37Å; D251-M422 WeakPolarHBondContact OD1-CG 3.21Å
252G98.1Very high97Very high0 Ų019.5 Ų19.50%012%0.118CC..Hα-helixtrans-58.1-40.9177.700000114T248 L249 A250 E254 Y255 I256T248-G252 PolarHBondContact O-N 3.43Å; L249-G252 PolarHBondContact O-N 3.25Å; A250-G252 VanDerWaalsContact C-N 3.34Å; G252-E254 VanDerWaalsContact C-N 3.34Å; G252-Y255 PolarHBondContact O-N 2.87Å; G252-I256 WeakPolarHBondContact O-CG1 3.27Å; G252-I256 PolarHBondContact O-N 2.76Å
253I97.9Very high96.6Very high16 Ų1622.5 Ų22.58%0.08215%0.15CC..Hα-helixtrans-63-42174.5-70.9164.7000110.4L249 A250 D251 I256 K257 A300 F304 I413L249-I253 VanDerWaalsContact O-CG1 3.31Å; L249-I253 WeakPolarHBondContact O-CG1 3.44Å; L249-I253 PolarHBondContact O-N 3.39Å; A250-I253 PolarHBondContact O-N 2.92Å; D251-I253 VanDerWaalsContact C-N 3.33Å; D251-I253 PolarHBondContact O-N 3.24Å; I253-I256 PolarHBondContact O-N 3.02Å; I253-K257 HydrophobicContact CG2-CD 4.26Å; I253-K257 WeakPolarHBondContact O-CG 3.44Å; I253-K257 PolarHBondContact O-N 3.22Å; I253-A300 HydrophobicContact CD1-CB 3.98Å; I253-A300 HydrophobicContact CG1-CB 4.15Å; I253-F304 HydrophobicContact CG2-CE2 4.42Å; I253-F304 HydrophobicContact CG2-CZ 4.11Å; I253-I413 HydrophobicContact CD1-CG2 4.45Å
254E97Very high96.4Very high36 Ų3623.1 Ų23.117%0.16815%0.154CC..Hα-helixtrans-65.9-40178-158.663.5-155.700111.9L190 M207 A250 D251 G252 K257 A258 M422 A423L190-E254 HydrophobicContact CD1-CB 3.89Å; L190-E254 HydrophobicContact CD1-CG 4.09Å; M207-E254 HydrophobicContact CE-CG 4.26Å; A250-E254 PolarHBondContact O-N 3.42Å; D251-E254 WeakPolarHBondContact O-CB 3.38Å; D251-E254 PolarHBondContact O-N 3.24Å; D251-E254 VanDerWaalsContact O-N 3.07Å; G252-E254 VanDerWaalsContact C-N 3.34Å; E254-K257 PolarHBondContact O-N 3.3Å; E254-K257 IonicContact OE2-NZ 3.84Å; E254-A258 WeakPolarHBondContact O-CB 3.45Å; E254-A258 PolarHBondContact O-N 3.26Å; E254-M422 HydrophobicContact CB-CB 4.34Å; E254-A423 HydrophobicContact CG-CB 4.26Å
255Y97.6Very high96.2Very high1 Ų129.9 Ų29.90%0.00418%0.183CC..Hα-helixtrans-64.2-39173.5-66.7-49.9000113D188 I189 L190 M207 I210 I227 I229 D251 G252 A258 A259D188-Y255 WeakPolarHBondContact CA-OH 3.49Å; D188-Y255 WeakPolarHBondContact OD1-CE2 3.39Å; D188-Y255 PolarHBondContact OD1-OH 3.19Å; I189-Y255 PolarHBondContact N-OH 2.96Å; L190-Y255 WeakPolarHBondContact CB-OH 3.43Å; L190-Y255 HydrophobicContact CD1-CE1 3.95Å; L190-Y255 HydrophobicContact CD1-CE2 4.2Å; L190-Y255 HydrophobicContact CG-CE1 4.01Å; L190-Y255 WeakPolarHBondContact CG-OH 3.36Å; L190-Y255 PolarHBondContact N-OH 3.25Å; M207-Y255 HydrophobicContact CE-CD1 3.55Å; M207-Y255 HydrophobicContact CE-CE1 3.71Å; M207-Y255 HydrophobicContact SD-CD1 4.07Å; M207-Y255 HydrophobicContact SD-CE1 3.58Å; M207-Y255 VanDerWaalsContact SD-CE1 3.58Å; I210-Y255 HydrophobicContact CD1-CD1 4.13Å; I210-Y255 HydrophobicContact CD1-CE1 3.38Å; I210-Y255 HydrophobicContact CG2-CD1 3.98Å; I210-Y255 HydrophobicContact CG2-CE1 4.29Å; I227-Y255 HydrophobicContact CD1-CD1 3.89Å; I227-Y255 HydrophobicContact CD1-CD2 3.49Å; I227-Y255 VanDerWaalsContact CD1-CD2 3.49Å; I227-Y255 HydrophobicContact CD1-CE1 3.97Å; I227-Y255 HydrophobicContact CD1-CE2 3.54Å; I227-Y255 HydrophobicContact CD1-CG 3.67Å; I229-Y255 HydrophobicContact CG1-CD2 4.06Å; I229-Y255 HydrophobicContact CG1-CE2 4.46Å; I229-Y255 HydrophobicContact CG2-CD2 4.46Å; I229-Y255 HydrophobicContact CG2-CE2 4.44Å; D251-Y255 HydrophobicContact CB-CD2 4.44Å; D251-Y255 HydrophobicContact CB-CE2 4Å; D251-Y255 WeakPolarHBondContact O-CD2 3.11Å; D251-Y255 PolarHBondContact O-N 3.35Å; G252-Y255 PolarHBondContact O-N 2.87Å; Y255-A258 PolarHBondContact O-N 2.88Å; Y255-A259 WeakPolarHBondContact O-CB 3.46Å; Y255-A259 PolarHBondContact O-N 3.16Å
256I97.3Very high96.1Very high0 Ų030.6 Ų30.60%019%0.186CC..Hα-helixtrans-61.1-48.4172.5-75171.5000110.4G252 I253 A258 A259 I260 I266 F269 L273 W297 V301 F304G252-I256 WeakPolarHBondContact O-CG1 3.27Å; G252-I256 PolarHBondContact O-N 2.76Å; I253-I256 PolarHBondContact O-N 3.02Å; I256-A258 VanDerWaalsContact C-N 3.29Å; I256-A258 PolarHBondContact O-N 3.36Å; I256-A259 PolarHBondContact O-N 2.92Å; I256-I260 HydrophobicContact CG2-CD1 3.63Å; I256-I260 HydrophobicContact CG2-CG1 4.37Å; I256-I260 WeakPolarHBondContact O-CG1 3.49Å; I256-I260 PolarHBondContact O-N 2.63Å; I256-I266 HydrophobicContact CD1-CD1 4.05Å; I256-I266 HydrophobicContact CG1-CD1 4.11Å; I256-I266 HydrophobicContact CG2-CD1 3.75Å; I256-F269 HydrophobicContact CB-CZ 4.39Å; I256-F269 HydrophobicContact CG1-CE2 4.02Å; I256-F269 HydrophobicContact CG1-CZ 4.22Å; I256-F269 HydrophobicContact CG2-CZ 4.27Å; I256-L273 HydrophobicContact CD1-CD1 4.24Å; I256-L273 HydrophobicContact CG1-CD1 3.9Å; I256-W297 HydrophobicContact CD1-CH2 3.37Å; I256-W297 HydrophobicContact CD1-CZ2 3.9Å; I256-W297 HydrophobicContact CD1-CZ3 4.11Å; I256-W297 HydrophobicContact CG1-CH2 4.23Å; I256-V301 HydrophobicContact CD1-CG2 3.87Å; I256-F304 HydrophobicContact CB-CE2 4.5Å; I256-F304 HydrophobicContact CB-CZ 4.4Å; I256-F304 HydrophobicContact CD1-CE2 4.48Å; I256-F304 HydrophobicContact CG2-CD1 3.67Å; I256-F304 HydrophobicContact CG2-CD2 3.92Å; I256-F304 HydrophobicContact CG2-CE1 3.65Å; I256-F304 HydrophobicContact CG2-CE2 3.9Å; I256-F304 HydrophobicContact CG2-CG 3.8Å; I256-F304 HydrophobicContact CG2-CZ 3.76Å
257K95.9Very high96.1Very high68 Ų6832.8 Ų32.830%0.29620%0.198SC..Hα-helixtrans-58.4-41.8178.1-71.2169.5-176.2167.40111.4I253 E254 S261 F304 D417I253-K257 HydrophobicContact CG2-CD 4.26Å; I253-K257 WeakPolarHBondContact O-CG 3.44Å; I253-K257 PolarHBondContact O-N 3.22Å; E254-K257 PolarHBondContact O-N 3.3Å; E254-K257 IonicContact OE2-NZ 3.84Å; K257-S261 WeakPolarHBondContact O-CB 3.38Å; K257-S261 PolarHBondContact O-N 3.48Å; K257-S261 PolarHBondContact O-OG 3.41Å; K257-F304 HydrophobicContact CG-CE1 4.07Å; K257-F304 HydrophobicContact CG-CZ 4.12Å; K257-D417 IonicContact NZ-OD1 2.85Å
258A94.6Very high95.9Very high23 Ų2337 Ų3719%0.1922%0.221CC..Hα-helixtrans-64.2-47.1177.900000112.4M207 E254 Y255 I256 S261 A262M207-A258 HydrophobicContact CE-CB 3.8Å; E254-A258 WeakPolarHBondContact O-CB 3.45Å; E254-A258 PolarHBondContact O-N 3.26Å; Y255-A258 PolarHBondContact O-N 2.88Å; I256-A258 VanDerWaalsContact C-N 3.29Å; I256-A258 PolarHBondContact O-N 3.36Å; A258-S261 PolarHBondContact O-N 3.27Å; A258-A262 PolarHBondContact O-N 2.89Å
259A94.9Very high95.7Very high0 Ų037 Ų370%022%0.221CC..Hα-helixtrans-63.1-42.1177.700000112.6I214 Y255 I256 S261 A262 G263 L264 F269I214-A259 HydrophobicContact CD1-CB 4.36Å; Y255-A259 WeakPolarHBondContact O-CB 3.46Å; Y255-A259 PolarHBondContact O-N 3.16Å; I256-A259 PolarHBondContact O-N 2.92Å; A259-S261 VanDerWaalsContact C-N 3.35Å; A259-A262 PolarHBondContact O-N 2.93Å; A259-G263 PolarHBondContact O-N 3.4Å; A259-L264 HydrophobicContact CB-CD1 4.07Å; A259-L264 WeakPolarHBondContact O-CB 3.33Å; A259-L264 PolarHBondContact O-N 3.25Å; A259-F269 HydrophobicContact CB-CD1 4.15Å; A259-F269 HydrophobicContact CB-CD2 4.1Å; A259-F269 HydrophobicContact CB-CE1 3.71Å; A259-F269 HydrophobicContact CB-CE2 3.66Å; A259-F269 HydrophobicContact CB-CG 4.33Å; A259-F269 HydrophobicContact CB-CZ 3.47Å; A259-F269 VanDerWaalsContact CB-CZ 3.47Å
260I95.9Very high95.6Very high65 Ų6537.2 Ų37.233%0.33322%0.222SC..Hα-helixtrans-64.3-41.4175.2-68.7172000110.8I256 A262 G263 F269 F304I256-I260 HydrophobicContact CG2-CD1 3.63Å; I256-I260 HydrophobicContact CG2-CG1 4.37Å; I256-I260 WeakPolarHBondContact O-CG1 3.49Å; I256-I260 PolarHBondContact O-N 2.63Å; I260-A262 PolarHBondContact O-N 3.29Å; I260-G263 WeakPolarHBondContact O-CA 3.39Å; I260-G263 PolarHBondContact O-N 3.42Å; I260-F269 HydrophobicContact CG1-CE1 4.33Å; I260-F269 HydrophobicContact CG1-CZ 4.42Å; I260-F304 HydrophobicContact CD1-CD1 3.67Å; I260-F304 HydrophobicContact CD1-CE1 4.26Å; I260-F304 HydrophobicContact CD1-CG 4.41Å
261S91.9Very high95.6Very high107 Ų10737.9 Ų37.975%0.74823%0.227SC*.Hα-helixtrans-63.8-26.1176.8-59.60000112.6K257 A258 A259 G263K257-S261 WeakPolarHBondContact O-CB 3.38Å; K257-S261 PolarHBondContact O-N 3.48Å; K257-S261 PolarHBondContact O-OG 3.41Å; A258-S261 PolarHBondContact O-N 3.27Å; A259-S261 VanDerWaalsContact C-N 3.35Å; S261-G263 VanDerWaalsContact C-N 3.26Å
262A88.8Confident95.5Very high57 Ų5742 Ų4247%0.47124%0.242SC..THydrogen-bonded Turntrans-822.6171.800000113.9A211 A258 A259 I260A211-A262 HydrophobicContact CB-CB 4Å; A258-A262 PolarHBondContact O-N 2.89Å; A259-A262 PolarHBondContact O-N 2.93Å; I260-A262 PolarHBondContact O-N 3.29Å
263G91.7Very high95.5Very high67 Ų6742.1 Ų42.169%0.69124%0.243SC*.THydrogen-bonded Turntrans94.17.417400000115.6A259 I260 S261A259-G263 PolarHBondContact O-N 3.4Å; I260-G263 WeakPolarHBondContact O-CA 3.39Å; I260-G263 PolarHBondContact O-N 3.42Å; S261-G263 VanDerWaalsContact C-N 3.26Å
264L93.3Very high95.5Very high30 Ų3041.9 Ų41.916%0.15724%0.242CC..  trans-81.7143.3176.7-58.4172.3000111.2I214 A215 A259 F269I214-L264 HydrophobicContact CB-CD1 4.27Å; I214-L264 HydrophobicContact CG2-CD1 3.59Å; A215-L264 HydrophobicContact CB-CD1 4.13Å; A215-L264 HydrophobicContact CB-CD2 4.16Å; A215-L264 HydrophobicContact CB-CG 4.49Å; A259-L264 HydrophobicContact CB-CD1 4.07Å; A259-L264 WeakPolarHBondContact O-CB 3.33Å; A259-L264 PolarHBondContact O-N 3.25Å; L264-F269 HydrophobicContact CB-CD1 3.88Å; L264-F269 HydrophobicContact CB-CE1 4.2Å; L264-F269 HydrophobicContact CD1-CD1 4.39Å
265K95.6Very high95.6Very high153 Ų15340.2 Ų40.267%0.66524%0.235SC*.  trans-84.3145.7171-56.2173.9-179.1172.90109.4D267 D268 F269K265-D267 VanDerWaalsContact C-N 3.26Å; K265-D267 PolarHBondContact O-N 2.79Å; K265-D267 VanDerWaalsContact O-N 3.15Å; K265-D268 VanDerWaalsContact CB-OD2 3.32Å; K265-D268 WeakPolarHBondContact CB-OD2 3.45Å; K265-D268 PolarHBondContact N-OD2 3Å; K265-D268 WeakPolarHBondContact O-CB 3.33Å; K265-D268 PolarHBondContact O-N 3.48Å; K265-F269 VanDerWaalsContact O-CD1 3.23Å; K265-F269 WeakPolarHBondContact O-CD1 3.23Å
266I96.9Very high95.6Very high14 Ų1440.5 Ų40.57%0.07224%0.236CC..Hα-helixtrans-49-45.5-176.3-175.963.9000113.1I256 D268 F269 A270 V301 F304 A306I256-I266 HydrophobicContact CD1-CD1 4.05Å; I256-I266 HydrophobicContact CG1-CD1 4.11Å; I256-I266 HydrophobicContact CG2-CD1 3.75Å; I266-D268 VanDerWaalsContact C-N 3.28Å; I266-D268 PolarHBondContact O-N 3.38Å; I266-F269 HydrophobicContact CD1-CE1 4.35Å; I266-F269 HydrophobicContact CD1-CE2 4.49Å; I266-F269 HydrophobicContact CD1-CZ 3.89Å; I266-F269 PolarHBondContact O-N 3.38Å; I266-A270 HydrophobicContact CD1-CB 3.81Å; I266-A270 HydrophobicContact CG1-CB 4.09Å; I266-A270 WeakPolarHBondContact O-CB 3.43Å; I266-A270 PolarHBondContact O-N 3.05Å; I266-V301 HydrophobicContact CD1-CG1 4.39Å; I266-V301 HydrophobicContact CG1-CG1 4.34Å; I266-F304 HydrophobicContact CD1-CB 4.36Å; I266-F304 HydrophobicContact CG1-CB 4.29Å; I266-A306 HydrophobicContact CG1-CB 3.97Å; I266-A306 HydrophobicContact CG2-CB 4.05Å
267D96.9Very high95.7Very high46 Ų4640.5 Ų40.525%0.24624%0.236CC..Hα-helixtrans-74.7-12.5-178.2-65.1-44.4000114K265 F269 P271 Q307 D308 S311K265-D267 VanDerWaalsContact C-N 3.26Å; K265-D267 PolarHBondContact O-N 2.79Å; K265-D267 VanDerWaalsContact O-N 3.15Å; D267-F269 VanDerWaalsContact C-N 3.32Å; D267-P271 WeakPolarHBondContact O-CD 3.46Å; D267-Q307 PolarHBondContact OD1-N 3.38Å; D267-Q307 PolarHBondContact OD2-N 3.12Å; D267-D308 HydrophobicContact CB-CB 4.33Å; D267-D308 PolarHBondContact OD1-N 3.21Å; D267-D308 VanDerWaalsContact OD1-N 3.14Å; D267-D308 PolarHBondContact OD2-N 3.09Å; D267-S311 WeakPolarHBondContact OD1-CB 3.4Å; D267-S311 PolarHBondContact OD1-OG 2.88Å
268D94.3Very high95.8Very high90 Ų9037.3 Ų37.348%0.48122%0.223SC..Hα-helixtrans-77.9-18.2177.3-61.6-24.1000112.2S218 K265 I266S218-D268 PolarHBondContact OG-O 2.89Å; K265-D268 VanDerWaalsContact CB-OD2 3.32Å; K265-D268 WeakPolarHBondContact CB-OD2 3.45Å; K265-D268 PolarHBondContact N-OD2 3Å; K265-D268 WeakPolarHBondContact O-CB 3.33Å; K265-D268 PolarHBondContact O-N 3.48Å; I266-D268 VanDerWaalsContact C-N 3.28Å; I266-D268 PolarHBondContact O-N 3.38Å
269F96Very high96Very high0 Ų036.2 Ų36.20%021%0.214CC..Hα-helixtrans-135.9-31-177.373.7-88.2000114.9I214 I256 A259 I260 L264 K265 I266 D267 P271 R272 L273I214-F269 HydrophobicContact CG2-CB 3.48Å; I214-F269 VanDerWaalsContact CG2-CB 3.48Å; I214-F269 HydrophobicContact CG2-CD2 4.09Å; I214-F269 HydrophobicContact CG2-CG 3.88Å; I256-F269 HydrophobicContact CB-CZ 4.39Å; I256-F269 HydrophobicContact CG1-CE2 4.02Å; I256-F269 HydrophobicContact CG1-CZ 4.22Å; I256-F269 HydrophobicContact CG2-CZ 4.27Å; A259-F269 HydrophobicContact CB-CD1 4.15Å; A259-F269 HydrophobicContact CB-CD2 4.1Å; A259-F269 HydrophobicContact CB-CE1 3.71Å; A259-F269 HydrophobicContact CB-CE2 3.66Å; A259-F269 HydrophobicContact CB-CG 4.33Å; A259-F269 HydrophobicContact CB-CZ 3.47Å; A259-F269 VanDerWaalsContact CB-CZ 3.47Å; I260-F269 HydrophobicContact CG1-CE1 4.33Å; I260-F269 HydrophobicContact CG1-CZ 4.42Å; L264-F269 HydrophobicContact CB-CD1 3.88Å; L264-F269 HydrophobicContact CB-CE1 4.2Å; L264-F269 HydrophobicContact CD1-CD1 4.39Å; K265-F269 VanDerWaalsContact O-CD1 3.23Å; K265-F269 WeakPolarHBondContact O-CD1 3.23Å; I266-F269 HydrophobicContact CD1-CE1 4.35Å; I266-F269 HydrophobicContact CD1-CE2 4.49Å; I266-F269 HydrophobicContact CD1-CZ 3.89Å; I266-F269 PolarHBondContact O-N 3.38Å; D267-F269 VanDerWaalsContact C-N 3.32Å; F269-P271 VanDerWaalsContact C-CD 3.4Å; F269-P271 VanDerWaalsContact C-N 3.32Å; F269-R272 WeakPolarHBondContact O-CA 3.24Å; F269-R272 PolarHBondContact O-N 3.25Å; F269-L273 HydrophobicContact CD2-CD1 4.22Å; F269-L273 HydrophobicContact CD2-CD2 4.08Å; F269-L273 HydrophobicContact CD2-CG 4.23Å; F269-L273 HydrophobicContact CE2-CD1 4.01Å; F269-L273 HydrophobicContact CE2-CD2 4.43Å; F269-L273 PolarHBondContact O-N 2.96Å
270A97.1Very high96.2Very high4 Ų437.1 Ų37.13%0.03322%0.223CC..G310 helixtrans-53.9-38.8-178.700000114I266 R272 L273I266-A270 HydrophobicContact CD1-CB 3.81Å; I266-A270 HydrophobicContact CG1-CB 4.09Å; I266-A270 WeakPolarHBondContact O-CB 3.43Å; I266-A270 PolarHBondContact O-N 3.05Å; A270-R272 PolarHBondContact O-N 3.29Å; A270-L273 HydrophobicContact CB-CD1 4.33Å; A270-L273 WeakPolarHBondContact O-CB 3.17Å; A270-L273 PolarHBondContact O-N 3.09Å
271P96.9Very high96.3Very high19 Ų1937.9 Ų37.912%0.12323%0.226CC..G310 helixtrans-61.5-8.6175.1-25.636.5000115.2D267 F269 K310 R315D267-P271 WeakPolarHBondContact O-CD 3.46Å; F269-P271 VanDerWaalsContact C-CD 3.4Å; F269-P271 VanDerWaalsContact C-N 3.32Å; P271-K310 HydrophobicContact CB-CB 4.07Å; P271-K310 HydrophobicContact CG-CB 4.26Å; P271-R315 VanDerWaalsContact O-CZ 3.22Å; P271-R315 PolarHBondContact O-NH2 3.04Å
272R96.6Very high96.6Very high85 Ų8536 Ų3632%0.32121%0.207SC..G310 helixtrans-110.7-2.6176.1-64.2-56.6177.2-142.43.2114.5P222 F224 N225 T226 F269 A270 R315P222-R272 PolarHBondContact O-NE 2.57Å; P222-R272 PolarHBondContact O-NH2 3.27Å; F224-R272 WeakPolarHBondContact O-CD 3.38Å; N225-R272 VanDerWaalsContact CA-O 3.27Å; N225-R272 WeakPolarHBondContact CA-O 3.31Å; N225-R272 WeakPolarHBondContact CB-O 3.42Å; T226-R272 PolarHBondContact N-O 3.47Å; F269-R272 WeakPolarHBondContact O-CA 3.24Å; F269-R272 PolarHBondContact O-N 3.25Å; A270-R272 PolarHBondContact O-N 3.29Å; R272-R315 VanDerWaalsContact C-NH2 3.32Å
273L97.8Very high97Very high4 Ų435 Ų352%0.02119%0.194CC..EExtended strand (participates in β ladder)trans-69.1134.6167.2-57.1178.2000110I227 I229 I256 F269 A270 W297 R315I227-L273 HydrophobicContact CG2-CD2 3.25Å; I227-L273 HydrophobicContact CG2-CG 4.48Å; I229-L273 HydrophobicContact CD1-CB 4.38Å; I256-L273 HydrophobicContact CD1-CD1 4.24Å; I256-L273 HydrophobicContact CG1-CD1 3.9Å; F269-L273 HydrophobicContact CD2-CD1 4.22Å; F269-L273 HydrophobicContact CD2-CD2 4.08Å; F269-L273 HydrophobicContact CD2-CG 4.23Å; F269-L273 HydrophobicContact CE2-CD1 4.01Å; F269-L273 HydrophobicContact CE2-CD2 4.43Å; F269-L273 PolarHBondContact O-N 2.96Å; A270-L273 HydrophobicContact CB-CD1 4.33Å; A270-L273 WeakPolarHBondContact O-CB 3.17Å; A270-L273 PolarHBondContact O-N 3.09Å; L273-W297 HydrophobicContact CD1-CH2 4.13Å; L273-W297 HydrophobicContact CD1-CZ2 3.91Å; L273-R315 PolarHBondContact O-NH2 2.98Å
274S97.9Very high97.3Very high10 Ų1036.2 Ų36.27%0.0718%0.181CC..EExtended strand (participates in β ladder)trans-131.4164.3175.163.80000110.3I227 S228 I229 R315I227-S274 PolarHBondContact O-N 2.81Å; I227-S274 VanDerWaalsContact O-N 3.16Å; I227-S274 PolarHBondContact O-OG 3.25Å; S228-S274 CarbonylContact C-O 3.52Å; S228-S274 WeakPolarHBondContact CA-O 3.34Å; I229-S274 PolarHBondContact N-O 2.89Å; S274-R315 CarbonylContact C-O 3.42Å; S274-R315 WeakPolarHBondContact CA-O 3.46Å
275F98.8Very high97.6Very high1 Ų134.8 Ų34.80%0.00417%0.173CC..EExtended strand (participates in β ladder)trans-123.7162.4-174.9-73.7-98000111.6I229 T248 L249 F277 W297 L314 R315 T316 H317I229-F275 HydrophobicContact CB-CD1 3.84Å; I229-F275 HydrophobicContact CB-CE1 3.82Å; I229-F275 HydrophobicContact CB-CG 4.4Å; I229-F275 HydrophobicContact CB-CZ 4.39Å; I229-F275 HydrophobicContact CD1-CE1 3.9Å; I229-F275 HydrophobicContact CD1-CE2 4.01Å; I229-F275 HydrophobicContact CD1-CZ 3.6Å; I229-F275 HydrophobicContact CG1-CE1 4.48Å; I229-F275 HydrophobicContact CG2-CD1 4.19Å; I229-F275 HydrophobicContact CG2-CE1 3.89Å; I229-F275 CarbonylContact O-C 3.53Å; I229-F275 WeakPolarHBondContact O-CA 3.47Å; T248-F275 HydrophobicContact CG2-CD1 3.79Å; T248-F275 HydrophobicContact CG2-CE1 4.16Å; L249-F275 HydrophobicContact CD2-CD1 4.47Å; L249-F275 HydrophobicContact CD2-CE1 3.74Å; L249-F275 HydrophobicContact CD2-CZ 4.2Å; F275-F277 HydrophobicContact CB-CE2 4.07Å; F275-F277 HydrophobicContact CD1-CE2 4.38Å; F275-F277 HydrophobicContact CD1-CZ 4.39Å; F275-W297 HydrophobicContact CE1-CE3 4.36Å; F275-W297 HydrophobicContact CE1-CZ3 4.5Å; F275-W297 AromaticContact CE2-CD2 3.9Å; F275-W297 HydrophobicContact CE2-CD2 3.9Å; F275-W297 AromaticContact CE2-CE2 3.65Å; F275-W297 HydrophobicContact CE2-CE3 4.37Å; F275-W297 HydrophobicContact CE2-CG 4.33Å; F275-W297 HydrophobicContact CE2-CH2 4.29Å; F275-W297 AromaticContact CE2-CZ2 3.86Å; F275-W297 HydrophobicContact CE2-CZ2 3.86Å; F275-W297 AromaticContact CZ-CD2 3.53Å; F275-W297 HydrophobicContact CZ-CD2 3.53Å; F275-W297 AromaticContact CZ-CE2 3.65Å; F275-W297 AromaticContact CZ-CE3 3.55Å; F275-W297 HydrophobicContact CZ-CE3 3.55Å; F275-W297 HydrophobicContact CZ-CG 4.22Å; F275-W297 AromaticContact CZ-CH2 3.73Å; F275-W297 HydrophobicContact CZ-CH2 3.73Å; F275-W297 AromaticContact CZ-CZ2 3.75Å; F275-W297 HydrophobicContact CZ-CZ2 3.75Å; F275-W297 AromaticContact CZ-CZ3 3.66Å; F275-W297 HydrophobicContact CZ-CZ3 3.66Å; F275-L314 HydrophobicContact CB-CD1 4.48Å; F275-L314 HydrophobicContact CB-CD2 4.2Å; F275-L314 HydrophobicContact CB-CG 4.21Å; F275-L314 HydrophobicContact CD1-CD1 3.9Å; F275-L314 HydrophobicContact CD1-CG 4.38Å; F275-L314 HydrophobicContact CD2-CB 4.39Å; F275-L314 HydrophobicContact CD2-CD1 3.82Å; F275-L314 HydrophobicContact CD2-CD2 4.32Å; F275-L314 HydrophobicContact CD2-CG 3.47Å; F275-L314 VanDerWaalsContact CD2-CG 3.47Å; F275-L314 HydrophobicContact CE1-CD1 4.04Å; F275-L314 HydrophobicContact CE2-CB 4.45Å; F275-L314 HydrophobicContact CE2-CD1 3.93Å; F275-L314 HydrophobicContact CE2-CG 3.85Å; F275-L314 HydrophobicContact CG-CD1 3.78Å; F275-L314 HydrophobicContact CG-CD2 4.27Å; F275-L314 HydrophobicContact CG-CG 3.75Å; F275-L314 HydrophobicContact CZ-CD1 4.04Å; F275-L314 HydrophobicContact CZ-CG 4.46Å; F275-R315 PolarHBondContact N-O 3.39Å; F275-T316 CarbonylContact O-C 3.56Å; F275-T316 VanDerWaalsContact O-CA 3.29Å; F275-T316 WeakPolarHBondContact O-CA 3.41Å; F275-T316 PolarHBondContact O-OG1 3.4Å; F275-H317 PolarHBondContact O-N 2.91Å
276F98.6Very high97.7Very high7 Ų727.7 Ų27.73%0.03114%0.142CC..EExtended strand (participates in β ladder)trans-146.6107.7178.4174.4-152.1000111.9S228 I229 S230 G231 Y232 H233 H317 Q319S228-F276 WeakPolarHBondContact OG-CB 3.37Å; I229-F276 PolarHBondContact O-N 3.18Å; S230-F276 CarbonylContact C-O 3.57Å; S230-F276 WeakPolarHBondContact CA-O 3.5Å; G231-F276 PolarHBondContact N-O 3.2Å; Y232-F276 AromaticContact CD1-CE1 3.68Å; Y232-F276 HydrophobicContact CD1-CE1 3.68Å; Y232-F276 HydrophobicContact CD1-CE2 4.49Å; Y232-F276 AromaticContact CD1-CZ 3.53Å; Y232-F276 HydrophobicContact CD1-CZ 3.53Å; Y232-F276 HydrophobicContact CD2-CE2 4.18Å; Y232-F276 AromaticContact CD2-CZ 3.91Å; Y232-F276 HydrophobicContact CD2-CZ 3.91Å; Y232-F276 HydrophobicContact CE1-CZ 4.28Å; Y232-F276 AromaticContact CG-CE1 3.76Å; Y232-F276 HydrophobicContact CG-CE1 3.76Å; Y232-F276 AromaticContact CG-CE2 3.85Å; Y232-F276 HydrophobicContact CG-CE2 3.85Å; Y232-F276 AromaticContact CG-CZ 3.3Å; Y232-F276 HydrophobicContact CG-CZ 3.3Å; Y232-F276 PolarHBondContact N-O 3.33Å; Y232-F276 VanDerWaalsContact N-O 3.09Å; H233-F276 AromaticContact CE1-CD1 3.95Å; H233-F276 AromaticContact CE1-CE1 3.72Å; F276-H317 WeakPolarHBondContact CA-O 3.11Å; F276-H317 HydrophobicContact CB-CB 4.48Å; F276-H317 HydrophobicContact CD2-CB 4.15Å; F276-H317 AromaticContact CD2-CD2 3.45Å; F276-H317 VanDerWaalsContact CD2-CD2 3.45Å; F276-H317 WeakPolarHBondContact CD2-CD2 3.48Å; F276-H317 AromaticContact CE2-CD2 3.46Å; F276-H317 VanDerWaalsContact CE2-CD2 3.46Å; F276-H317 WeakPolarHBondContact CE2-CD2 3.25Å; F276-Q319 HydrophobicContact CE2-CB 3.42Å; F276-Q319 VanDerWaalsContact CE2-CB 3.42Å; F276-Q319 HydrophobicContact CZ-CB 3.67Å
277F98.8Very high97.8Very high0 Ų027 Ų270%014%0.139CC..EExtended strand (participates in β ladder)trans-105.6150.2179.1-69.7-76.3000112.6T248 F275 M289 L290 A293 L314 T316 H317 C318 Q319T248-F277 HydrophobicContact CG2-CE1 4Å; T248-F277 HydrophobicContact CG2-CZ 4.01Å; F275-F277 HydrophobicContact CB-CE2 4.07Å; F275-F277 HydrophobicContact CD1-CE2 4.38Å; F275-F277 HydrophobicContact CD1-CZ 4.39Å; F277-M289 HydrophobicContact CB-CE 4.02Å; F277-M289 HydrophobicContact CD1-CE 4.32Å; F277-M289 HydrophobicContact CG-CE 4.35Å; F277-L290 HydrophobicContact CB-CD2 3.91Å; F277-L290 HydrophobicContact CD2-CD2 3.71Å; F277-L290 HydrophobicContact CG-CD2 3.99Å; F277-A293 HydrophobicContact CE2-CB 3.98Å; F277-A293 HydrophobicContact CZ-CB 3.79Å; F277-L314 HydrophobicContact CE2-CD1 4.37Å; F277-L314 HydrophobicContact CE2-CD2 4.32Å; F277-T316 WeakPolarHBondContact CD2-OG1 3.06Å; F277-H317 PolarHBondContact N-O 3.28Å; F277-H317 VanDerWaalsContact N-O 3.16Å; F277-C318 WeakPolarHBondContact O-CA 3.37Å; F277-Q319 PolarHBondContact O-N 2.79Å; F277-Q319 VanDerWaalsContact O-N 3.15Å
278G98.6Very high97.9Very high2 Ų224.8 Ų24.82%0.02113%0.127CC..EExtended strand (participates in β ladder)trans-91.5141.6169.800000111.2Q244 N286 M289 Q319Q244-G278 PolarHBondContact OE1-O 3.2Å; G278-N286 PolarHBondContact O-OD1 3.02Å; G278-M289 WeakPolarHBondContact O-CE 3.41Å; G278-Q319 WeakPolarHBondContact CA-O 2.96Å
279I98.9Very high98.1Very high0 Ų020.5 Ų20.50%010%0.104CC..EExtended strand (participates in β ladder)trans-119.6108.3-174.7-53.8-64000109.6N286 M289 L290 C318 Q319 T320 S321 E340 A343 A344I279-N286 WeakPolarHBondContact CA-OD1 3.17Å; I279-N286 HydrophobicContact CD1-CB 4.35Å; I279-N286 HydrophobicContact CG2-CB 3.96Å; I279-M289 HydrophobicContact CD1-CE 3.95Å; I279-L290 HydrophobicContact CD1-CD1 3.9Å; I279-L290 HydrophobicContact CD1-CD2 4.31Å; I279-L290 HydrophobicContact CD1-CG 4.2Å; I279-C318 HydrophobicContact CD1-CB 4.41Å; I279-C318 HydrophobicContact CG1-CB 3.8Å; I279-Q319 PolarHBondContact N-O 3.11Å; I279-T320 CarbonylContact O-C 3.45Å; I279-S321 PolarHBondContact O-N 2.91Å; I279-E340 HydrophobicContact CG2-CB 4.14Å; I279-E340 WeakPolarHBondContact CG2-O 3.43Å; I279-E340 WeakPolarHBondContact O-CG 3.36Å; I279-A343 HydrophobicContact CG2-CB 3.66Å; I279-A344 HydrophobicContact CG1-CB 3.92Å; I279-A344 HydrophobicContact CG2-CB 4.38Å
280G98.3Very high98.3Very high19 Ų1920.6 Ų20.620%0.19611%0.105CC..  trans-96.2-173.2179.400000114.1D282 N286G280-D282 PolarHBondContact O-N 2.9Å; G280-N286 PolarHBondContact N-OD1 2.78Å; G280-N286 PolarHBondContact O-ND2 3.19Å
281M98.4Very high98.4Very high80 Ų8020.4 Ų20.439%0.39410%0.103SC..SBendtrans-69-21.2-170.6-73.7-61.1-57.800116.3L283 R336 I339 E340M281-L283 PolarHBondContact O-N 3.25Å; M281-R336 HydrophobicContact CE-CB 4.4Å; M281-R336 HydrophobicContact CE-CG 4.14Å; M281-R336 HydrophobicContact SD-CB 3.58Å; M281-R336 VanDerWaalsContact SD-CB 3.58Å; M281-R336 HydrophobicContact SD-CG 3.76Å; M281-I339 HydrophobicContact CE-CB 4.48Å; M281-I339 HydrophobicContact CE-CD1 4.02Å; M281-I339 HydrophobicContact CE-CG2 4.35Å; M281-E340 HydrophobicContact SD-CG 4.12Å
282D97.5Very high98.4Very high67 Ų6719.5 Ų19.536%0.35810%0.097SC..  trans-7691.4174.5-169.8-30.2000109.9G280 F284 M285 N286G280-D282 PolarHBondContact O-N 2.9Å; D282-F284 VanDerWaalsContact C-N 3.32Å; D282-F284 PolarHBondContact O-N 3.26Å; D282-F284 PolarHBondContact OD1-N 3.13Å; D282-M285 HydrophobicContact CB-CB 3.83Å; D282-M285 PolarHBondContact O-N 3.26Å; D282-M285 WeakPolarHBondContact OD1-CB 3.26Å; D282-M285 PolarHBondContact OD1-N 3.17Å; D282-N286 WeakPolarHBondContact O-CB 3.5Å; D282-N286 PolarHBondContact O-N 2.82Å; D282-N286 PolarHBondContact O-ND2 3.47Å
283L98.3Very high98.6Very high38 Ų3815.4 Ų15.420%0.1998%0.082CC..Hα-helixtrans-53.6-47.7-173.2-179.3152.3000112.3M281 V287 I339 L342 A343 L346M281-L283 PolarHBondContact O-N 3.25Å; L283-V287 VanDerWaalsContact O-CG2 3.32Å; L283-V287 WeakPolarHBondContact O-CG2 3.35Å; L283-V287 PolarHBondContact O-N 3.06Å; L283-V287 VanDerWaalsContact O-N 3.16Å; L283-I339 HydrophobicContact CB-CG2 4.23Å; L283-I339 HydrophobicContact CD1-CG2 4.12Å; L283-L342 HydrophobicContact CD1-CB 4.37Å; L283-A343 HydrophobicContact CG-CB 4.19Å; L283-L346 HydrophobicContact CD2-CD1 4.42Å
284F98.6Very high98.6Very high91 Ų9115.3 Ų15.340%0.3998%0.081SC..Hα-helixtrans-79.1-35.8-173-62-60.8000112.2D282 N286 V287 A288 Y397 I398 L401D282-F284 VanDerWaalsContact C-N 3.32Å; D282-F284 PolarHBondContact O-N 3.26Å; D282-F284 PolarHBondContact OD1-N 3.13Å; F284-N286 VanDerWaalsContact C-N 3.32Å; F284-N286 PolarHBondContact O-N 3.42Å; F284-V287 PolarHBondContact O-N 3.1Å; F284-A288 WeakPolarHBondContact O-CB 3.19Å; F284-A288 PolarHBondContact O-N 3.33Å; F284-Y397 HydrophobicContact CB-CE1 3.64Å; F284-Y397 AromaticContact CD2-CE1 3.74Å; F284-Y397 HydrophobicContact CD2-CE1 3.74Å; F284-Y397 HydrophobicContact CG-CD1 4.41Å; F284-Y397 AromaticContact CG-CE1 3.73Å; F284-Y397 HydrophobicContact CG-CE1 3.73Å; F284-I398 HydrophobicContact CB-CD1 3.84Å; F284-I398 HydrophobicContact CD1-CD1 3.52Å; F284-I398 HydrophobicContact CE1-CD1 4.41Å; F284-I398 HydrophobicContact CG-CD1 4.01Å; F284-L401 HydrophobicContact CB-CD2 4.34Å
285M98.7Very high98.6Very high0 Ų016.2 Ų16.20%08%0.083CC..Hα-helixtrans-60.2-43.4173-170.567.467.800111.1T29 E31 I33 C241 D282 A288 M289 L401 I405T29-M285 HydrophobicContact CG2-CE 3.83Å; E31-M285 HydrophobicContact CG-CE 4.22Å; E31-M285 HydrophobicContact CG-CG 4.44Å; E31-M285 HydrophobicContact CG-SD 4Å; E31-M285 WeakPolarHBondContact OE2-CE 3.34Å; I33-M285 HydrophobicContact CD1-CE 4.22Å; I33-M285 HydrophobicContact CD1-SD 4.14Å; C241-M285 HydrophobicContact CB-CG 3.66Å; C241-M285 HydrophobicContact CB-SD 4.4Å; C241-M285 WeakPolarHBondContact SG-CG 3.27Å; D282-M285 HydrophobicContact CB-CB 3.83Å; D282-M285 PolarHBondContact O-N 3.26Å; D282-M285 WeakPolarHBondContact OD1-CB 3.26Å; D282-M285 PolarHBondContact OD1-N 3.17Å; M285-A288 PolarHBondContact O-N 3.01Å; M285-M289 VanDerWaalsContact O-CB 3.31Å; M285-M289 WeakPolarHBondContact O-CB 3.33Å; M285-M289 PolarHBondContact O-N 3.18Å; M285-L401 HydrophobicContact CE-CD1 3.84Å; M285-L401 HydrophobicContact SD-CD1 3.92Å; M285-L401 HydrophobicContact SD-CD2 4.39Å; M285-L401 HydrophobicContact SD-CG 4.34Å; M285-I405 HydrophobicContact SD-CD1 3.68Å; M285-I405 HydrophobicContact SD-CG1 4.11Å
286N98.8Very high98.6Very high4 Ų416.4 Ų16.42%0.0218%0.084CC..Hα-helixtrans-68.5-36.1178.8-78.6-86.9000113G278 I279 G280 D282 F284 M289 L290 A343G278-N286 PolarHBondContact O-OD1 3.02Å; I279-N286 WeakPolarHBondContact CA-OD1 3.17Å; I279-N286 HydrophobicContact CD1-CB 4.35Å; I279-N286 HydrophobicContact CG2-CB 3.96Å; G280-N286 PolarHBondContact N-OD1 2.78Å; G280-N286 PolarHBondContact O-ND2 3.19Å; D282-N286 WeakPolarHBondContact O-CB 3.5Å; D282-N286 PolarHBondContact O-N 2.82Å; D282-N286 PolarHBondContact O-ND2 3.47Å; F284-N286 VanDerWaalsContact C-N 3.32Å; F284-N286 PolarHBondContact O-N 3.42Å; N286-M289 WeakPolarHBondContact O-CB 3.4Å; N286-M289 PolarHBondContact O-N 3.34Å; N286-L290 PolarHBondContact O-N 3.45Å; N286-A343 HydrophobicContact CB-CB 3.95Å
287V98.8Very high98.6Very high0 Ų016.3 Ų16.30%08%0.084CC..Hα-helixtrans-62.8-48.6171.7173.50000110.6L283 F284 M289 L290 R291 A343 L346 L392 I398L283-V287 VanDerWaalsContact O-CG2 3.32Å; L283-V287 WeakPolarHBondContact O-CG2 3.35Å; L283-V287 PolarHBondContact O-N 3.06Å; L283-V287 VanDerWaalsContact O-N 3.16Å; F284-V287 PolarHBondContact O-N 3.1Å; V287-M289 VanDerWaalsContact C-N 3.31Å; V287-M289 PolarHBondContact O-N 3.39Å; V287-L290 PolarHBondContact O-N 3.09Å; V287-R291 WeakPolarHBondContact O-CG 3.34Å; V287-R291 PolarHBondContact O-N 2.61Å; V287-A343 HydrophobicContact CG2-CB 4.41Å; V287-A343 WeakPolarHBondContact CG2-O 3.37Å; V287-L346 HydrophobicContact CG2-CB 3.69Å; V287-L392 HydrophobicContact CB-CD1 4.44Å; V287-L392 HydrophobicContact CG1-CD1 3.8Å; V287-L392 HydrophobicContact CG2-CD1 4.25Å; V287-I398 HydrophobicContact CG1-CG2 4.37Å
288A98.8Very high98.6Very high0 Ų016.5 Ų16.50%09%0.085CC..Hα-helixtrans-62.2-38.3178.600000112.1F284 M285 L290 R291 A292 L401 I405F284-A288 WeakPolarHBondContact O-CB 3.19Å; F284-A288 PolarHBondContact O-N 3.33Å; M285-A288 PolarHBondContact O-N 3.01Å; A288-L290 PolarHBondContact O-N 3.27Å; A288-R291 PolarHBondContact O-N 3.02Å; A288-A292 VanDerWaalsContact O-CB 3.31Å; A288-A292 WeakPolarHBondContact O-CB 3.3Å; A288-A292 PolarHBondContact O-N 2.86Å; A288-L401 HydrophobicContact CB-CB 4.02Å; A288-L401 HydrophobicContact CB-CD2 3.81Å; A288-L401 HydrophobicContact CB-CG 3.6Å; A288-I405 HydrophobicContact CB-CD1 3.6Å
289M98.8Very high98.5Very high0 Ų020.4 Ų20.40%010%0.103CC..Hα-helixtrans-56.2-51.3176.1-173.9-171.763.400111.8C241 Q244 V245 F277 G278 I279 M285 N286 V287 R291 A292 A293 I405C241-M289 HydrophobicContact CB-CB 4.12Å; C241-M289 HydrophobicContact CB-CG 4Å; C241-M289 HydrophobicContact CB-SD 3.72Å; Q244-M289 HydrophobicContact CB-SD 4.12Å; V245-M289 HydrophobicContact CG2-CB 4.47Å; V245-M289 HydrophobicContact CG2-CG 3.33Å; V245-M289 HydrophobicContact CG2-SD 4.36Å; F277-M289 HydrophobicContact CB-CE 4.02Å; F277-M289 HydrophobicContact CD1-CE 4.32Å; F277-M289 HydrophobicContact CG-CE 4.35Å; G278-M289 WeakPolarHBondContact O-CE 3.41Å; I279-M289 HydrophobicContact CD1-CE 3.95Å; M285-M289 VanDerWaalsContact O-CB 3.31Å; M285-M289 WeakPolarHBondContact O-CB 3.33Å; M285-M289 PolarHBondContact O-N 3.18Å; N286-M289 WeakPolarHBondContact O-CB 3.4Å; N286-M289 PolarHBondContact O-N 3.34Å; V287-M289 VanDerWaalsContact C-N 3.31Å; V287-M289 PolarHBondContact O-N 3.39Å; M289-R291 VanDerWaalsContact C-N 3.32Å; M289-R291 PolarHBondContact O-N 2.82Å; M289-A292 PolarHBondContact O-N 3.17Å; M289-A293 WeakPolarHBondContact O-CB 3.45Å; M289-A293 PolarHBondContact O-N 3.22Å; M289-I405 HydrophobicContact CB-CD1 4.35Å
290L98.9Very high98.4Very high1 Ų121.6 Ų21.61%0.00511%0.113CC..Hα-helixtrans-65.3-34.9-179.4-67.7177.9000112.6F277 I279 N286 V287 A288 R294 T316F277-L290 HydrophobicContact CB-CD2 3.91Å; F277-L290 HydrophobicContact CD2-CD2 3.71Å; F277-L290 HydrophobicContact CG-CD2 3.99Å; I279-L290 HydrophobicContact CD1-CD1 3.9Å; I279-L290 HydrophobicContact CD1-CD2 4.31Å; I279-L290 HydrophobicContact CD1-CG 4.2Å; N286-L290 PolarHBondContact O-N 3.45Å; V287-L290 PolarHBondContact O-N 3.09Å; A288-L290 PolarHBondContact O-N 3.27Å; L290-R294 PolarHBondContact O-N 3.23Å; L290-R294 PolarHBondContact O-NH1 3.06Å; L290-R294 VanDerWaalsContact O-NH1 3.15Å; L290-T316 HydrophobicContact CD2-CG2 4.3Å
291R98.8Very high98.4Very high0 Ų020.7 Ų20.70%010%0.103CC..Hα-helixtrans-68.1-45.7174.8-65.5173.787.5-1164111.3V60 V287 A288 M289 R294 Y295 D390 E399 T402V60-R291 HydrophobicContact CG1-CB 4.06Å; V287-R291 WeakPolarHBondContact O-CG 3.34Å; V287-R291 PolarHBondContact O-N 2.61Å; A288-R291 PolarHBondContact O-N 3.02Å; M289-R291 VanDerWaalsContact C-N 3.32Å; M289-R291 PolarHBondContact O-N 2.82Å; R291-R294 PolarHBondContact O-N 3.1Å; R291-Y295 PolarHBondContact O-N 2.9Å; R291-D390 IonicContact NE-OD1 3.03Å; R291-D390 IonicContact NE-OD2 2.93Å; R291-D390 IonicContact NH2-OD2 3.1Å; R291-D390 PolarHBondContact NH2-OD2 3.09Å; R291-E399 IonicContact CZ-OE1 2.76Å; R291-E399 IonicContact CZ-OE2 2.91Å; R291-E399 VanDerWaalsContact CZ-OE2 3.29Å; R291-E399 IonicContact NH1-OE1 2.67Å; R291-E399 IonicContact NH1-OE2 2.99Å; R291-E399 PolarHBondContact NH1-OE2 2.86Å; R291-E399 IonicContact NH2-OE1 3.35Å; R291-E399 PolarHBondContact NH2-OE1 3.28Å; R291-E399 IonicContact NH2-OE2 3.38Å; R291-E399 PolarHBondContact NH2-OE2 3.11Å; R291-T402 HydrophobicContact CB-CG2 3.62Å; R291-T402 PolarHBondContact NH1-OG1 2.98Å
292A98.8Very high98.3Very high0 Ų020 Ų200%011%0.106CC..Hα-helixtrans-64.4-40.8178.800000112.1A288 M289 R294 Y295 L296 T402 I405 V406A288-A292 VanDerWaalsContact O-CB 3.31Å; A288-A292 WeakPolarHBondContact O-CB 3.3Å; A288-A292 PolarHBondContact O-N 2.86Å; M289-A292 PolarHBondContact O-N 3.17Å; A292-R294 VanDerWaalsContact C-N 3.31Å; A292-R294 PolarHBondContact O-N 3.35Å; A292-Y295 WeakPolarHBondContact O-CB 3.14Å; A292-Y295 PolarHBondContact O-N 3.45Å; A292-L296 PolarHBondContact O-N 2.93Å; A292-T402 HydrophobicContact CB-CG2 4.05Å; A292-I405 HydrophobicContact CB-CB 3.94Å; A292-I405 HydrophobicContact CB-CG2 3.62Å; A292-V406 HydrophobicContact CB-CG2 3.7Å
293A98.9Very high98.2Very high0 Ų020.2 Ų20.20%012%0.124CC..Hα-helixtrans-57.9-42.4177.100000112.2V245 F277 M289 W297 L314V245-A293 HydrophobicContact CG1-CB 4.34Å; V245-A293 HydrophobicContact CG2-CB 4.26Å; F277-A293 HydrophobicContact CE2-CB 3.98Å; F277-A293 HydrophobicContact CZ-CB 3.79Å; M289-A293 WeakPolarHBondContact O-CB 3.45Å; M289-A293 PolarHBondContact O-N 3.22Å; A293-W297 VanDerWaalsContact O-CB 3.28Å; A293-W297 WeakPolarHBondContact O-CB 3.32Å; A293-W297 PolarHBondContact O-N 3.21Å; A293-L314 HydrophobicContact CB-CD1 4.12Å
294R98.8Very high98.1Very high1 Ų121.5 Ų21.50%0.00413%0.128CC..Hα-helixtrans-64-42.6177-69.6-172.5-68.3-91.87.8112.3P58 Y59 V60 L290 R291 A292 S298 L314 G347P58-R294 CarbonylContact O-C 3.15Å; Y59-R294 WeakPolarHBondContact O-CD 3.35Å; Y59-R294 PolarHBondContact O-NE 3.12Å; V60-R294 PolarHBondContact O-NE 2.82Å; V60-R294 VanDerWaalsContact O-NE 3.16Å; V60-R294 PolarHBondContact O-NH2 3.48Å; L290-R294 PolarHBondContact O-N 3.23Å; L290-R294 PolarHBondContact O-NH1 3.06Å; L290-R294 VanDerWaalsContact O-NH1 3.15Å; R291-R294 PolarHBondContact O-N 3.1Å; A292-R294 VanDerWaalsContact C-N 3.31Å; A292-R294 PolarHBondContact O-N 3.35Å; R294-S298 WeakPolarHBondContact O-CB 3.49Å; R294-S298 PolarHBondContact O-N 3.03Å; R294-L314 HydrophobicContact CG-CB 4.1Å; R294-L314 HydrophobicContact CG-CD2 4.03Å; R294-G347 VanDerWaalsContact CZ-O 3.28Å; R294-G347 PolarHBondContact NH1-O 2.67Å; R294-G347 PolarHBondContact NH2-O 3.38Å
295Y98.6Very high98Very high30 Ų3019.1 Ų19.112%0.11813%0.13CC..Hα-helixtrans-58.4-56.3177.3-178.2-81.5000111E48 V49 P58 V60 R291 A292 W297 S298 E299 V406E48-Y295 HydrophobicContact CB-CE2 4.42Å; E48-Y295 WeakPolarHBondContact O-CE2 3.44Å; E48-Y295 PolarHBondContact OE2-OH 2.92Å; V49-Y295 HydrophobicContact CG1-CD2 4.05Å; V49-Y295 HydrophobicContact CG1-CE2 4.37Å; V49-Y295 HydrophobicContact CG1-CG 4.33Å; P58-Y295 HydrophobicContact CB-CD2 3.82Å; P58-Y295 HydrophobicContact CB-CE2 4.2Å; P58-Y295 HydrophobicContact CB-CG 4.4Å; P58-Y295 HydrophobicContact CG-CD2 3.55Å; P58-Y295 HydrophobicContact CG-CE2 3.78Å; P58-Y295 WeakPolarHBondContact O-CA 3.41Å; V60-Y295 HydrophobicContact CG2-CD2 3.63Å; V60-Y295 HydrophobicContact CG2-CG 4.27Å; R291-Y295 PolarHBondContact O-N 2.9Å; A292-Y295 WeakPolarHBondContact O-CB 3.14Å; A292-Y295 PolarHBondContact O-N 3.45Å; Y295-W297 PolarHBondContact O-N 3.1Å; Y295-S298 PolarHBondContact O-N 2.77Å; Y295-E299 PolarHBondContact O-N 3.01Å; Y295-V406 HydrophobicContact CD1-CG1 3.92Å; Y295-V406 HydrophobicContact CD1-CG2 4.02Å; Y295-V406 HydrophobicContact CE1-CG1 4Å; Y295-V406 HydrophobicContact CG-CG2 4.29Å
296L98.6Very high97.8Very high5 Ų519.8 Ų19.83%0.02614%0.135CC..Hα-helixtrans-65.3-36.6-176.7-74.1171.3000112.5V245 L249 A292 E299 A300 V406 A409 R410V245-L296 HydrophobicContact CG1-CD1 3.77Å; L249-L296 HydrophobicContact CD1-CB 3.34Å; L249-L296 HydrophobicContact CD1-CD1 4.11Å; L249-L296 HydrophobicContact CD1-CG 4.39Å; A292-L296 PolarHBondContact O-N 2.93Å; L296-E299 PolarHBondContact O-N 3.01Å; L296-A300 WeakPolarHBondContact O-CB 3.07Å; L296-A300 PolarHBondContact O-N 2.84Å; L296-V406 HydrophobicContact CD2-CG1 3.93Å; L296-V406 HydrophobicContact CG-CG1 4.29Å; L296-V406 HydrophobicContact CG-CG2 4.35Å; L296-A409 HydrophobicContact CD1-CB 3.74Å; L296-R410 HydrophobicContact CD2-CB 4.26Å
297W98.6Very high97.6Very high4 Ų427 Ų272%0.01517%0.169CC..Hα-helixtrans-65.3-44.1175.1-178.7-107.4000112.3I229 L249 I256 L273 F275 A293 Y295 E299 A300 V301 L314I229-W297 HydrophobicContact CD1-CH2 4.42Å; L249-W297 HydrophobicContact CD2-CB 3.98Å; L249-W297 HydrophobicContact CD2-CD2 4.46Å; L249-W297 HydrophobicContact CD2-CE3 3.94Å; I256-W297 HydrophobicContact CD1-CH2 3.37Å; I256-W297 HydrophobicContact CD1-CZ2 3.9Å; I256-W297 HydrophobicContact CD1-CZ3 4.11Å; I256-W297 HydrophobicContact CG1-CH2 4.23Å; L273-W297 HydrophobicContact CD1-CH2 4.13Å; L273-W297 HydrophobicContact CD1-CZ2 3.91Å; F275-W297 HydrophobicContact CE1-CE3 4.36Å; F275-W297 HydrophobicContact CE1-CZ3 4.5Å; F275-W297 AromaticContact CE2-CD2 3.9Å; F275-W297 HydrophobicContact CE2-CD2 3.9Å; F275-W297 AromaticContact CE2-CE2 3.65Å; F275-W297 HydrophobicContact CE2-CE3 4.37Å; F275-W297 HydrophobicContact CE2-CG 4.33Å; F275-W297 HydrophobicContact CE2-CH2 4.29Å; F275-W297 AromaticContact CE2-CZ2 3.86Å; F275-W297 HydrophobicContact CE2-CZ2 3.86Å; F275-W297 AromaticContact CZ-CD2 3.53Å; F275-W297 HydrophobicContact CZ-CD2 3.53Å; F275-W297 AromaticContact CZ-CE2 3.65Å; F275-W297 AromaticContact CZ-CE3 3.55Å; F275-W297 HydrophobicContact CZ-CE3 3.55Å; F275-W297 HydrophobicContact CZ-CG 4.22Å; F275-W297 AromaticContact CZ-CH2 3.73Å; F275-W297 HydrophobicContact CZ-CH2 3.73Å; F275-W297 AromaticContact CZ-CZ2 3.75Å; F275-W297 HydrophobicContact CZ-CZ2 3.75Å; F275-W297 AromaticContact CZ-CZ3 3.66Å; F275-W297 HydrophobicContact CZ-CZ3 3.66Å; A293-W297 VanDerWaalsContact O-CB 3.28Å; A293-W297 WeakPolarHBondContact O-CB 3.32Å; A293-W297 PolarHBondContact O-N 3.21Å; Y295-W297 PolarHBondContact O-N 3.1Å; W297-E299 VanDerWaalsContact C-N 3.27Å; W297-E299 PolarHBondContact O-N 3.09Å; W297-A300 PolarHBondContact O-N 3.45Å; W297-V301 HydrophobicContact CD2-CG2 3.67Å; W297-V301 HydrophobicContact CE3-CG2 4.04Å; W297-V301 HydrophobicContact CG-CG2 4.26Å; W297-V301 HydrophobicContact CH2-CG2 3.88Å; W297-V301 HydrophobicContact CZ2-CG2 3.42Å; W297-V301 VanDerWaalsContact CZ2-CG2 3.42Å; W297-V301 HydrophobicContact CZ3-CG2 4.14Å; W297-V301 WeakPolarHBondContact O-CG2 3.4Å; W297-V301 PolarHBondContact O-N 3.19Å; W297-L314 HydrophobicContact CB-CB 3.98Å; W297-L314 HydrophobicContact CB-CD1 3.74Å; W297-L314 HydrophobicContact CB-CG 4.48Å; W297-L314 HydrophobicContact CG-CB 3.89Å; W297-L314 HydrophobicContact CG-CD1 4.04Å; W297-L314 HydrophobicContact CG-CG 4.46Å
298S98.3Very high97.5Very high4 Ų429.4 Ų29.43%0.02818%0.181CC..Hα-helixtrans-61.5-39.2176.8-1730000111.3R294 Y295 S302 L312R294-S298 WeakPolarHBondContact O-CB 3.49Å; R294-S298 PolarHBondContact O-N 3.03Å; Y295-S298 PolarHBondContact O-N 2.77Å; S298-S302 WeakPolarHBondContact O-CB 3.1Å; S298-S302 PolarHBondContact O-N 3.41Å; S298-S302 PolarHBondContact O-OG 3.1Å; S298-L312 VanDerWaalsContact O-CD2 3.26Å; S298-L312 WeakPolarHBondContact O-CD2 3.42Å
299E96.8Very high97.3Very high85 Ų8532.9 Ų32.940%0.39720%0.204SC..Hα-helixtrans-62.1-52.7173.7179.9178.482.400110.9Y295 L296 W297 V301 S302 G303 R410Y295-E299 PolarHBondContact O-N 3.01Å; L296-E299 PolarHBondContact O-N 3.01Å; W297-E299 VanDerWaalsContact C-N 3.27Å; W297-E299 PolarHBondContact O-N 3.09Å; E299-V301 PolarHBondContact O-N 2.98Å; E299-S302 WeakPolarHBondContact O-CB 3.48Å; E299-S302 PolarHBondContact O-N 2.65Å; E299-G303 PolarHBondContact O-N 2.91Å; E299-R410 IonicContact OE1-CZ 2.87Å; E299-R410 IonicContact OE1-NE 2.75Å; E299-R410 PolarHBondContact OE1-NE 2.99Å; E299-R410 IonicContact OE1-NH2 2.7Å; E299-R410 PolarHBondContact OE1-NH2 3.39Å; E299-R410 IonicContact OE2-CZ 2.85Å; E299-R410 IonicContact OE2-NE 3.88Å; E299-R410 IonicContact OE2-NH2 3.67Å; E299-R410 PolarHBondContact OE2-NH2 2.95Å
300A97.1Very high97.2Very high25 Ų2538.6 Ų38.621%0.20723%0.229CC..Hα-helixtrans-61.2-47.8-177.500000112.9I253 L296 W297 S302 G303 F304I253-A300 HydrophobicContact CD1-CB 3.98Å; I253-A300 HydrophobicContact CG1-CB 4.15Å; L296-A300 WeakPolarHBondContact O-CB 3.07Å; L296-A300 PolarHBondContact O-N 2.84Å; W297-A300 PolarHBondContact O-N 3.45Å; A300-S302 VanDerWaalsContact C-N 3.31Å; A300-S302 PolarHBondContact O-N 2.85Å; A300-G303 PolarHBondContact O-N 3.49Å; A300-G303 VanDerWaalsContact O-N 3.14Å; A300-F304 WeakPolarHBondContact O-CD2 3.4Å
301V97.7Very high97.1Very high0 Ų038.6 Ų38.60%023%0.229CC..Hα-helixtrans-67.8-31.6-178.8178.70000112.1I256 I266 W297 E299 G303 F304 A306 L312I256-V301 HydrophobicContact CD1-CG2 3.87Å; I266-V301 HydrophobicContact CD1-CG1 4.39Å; I266-V301 HydrophobicContact CG1-CG1 4.34Å; W297-V301 HydrophobicContact CD2-CG2 3.67Å; W297-V301 HydrophobicContact CE3-CG2 4.04Å; W297-V301 HydrophobicContact CG-CG2 4.26Å; W297-V301 HydrophobicContact CH2-CG2 3.88Å; W297-V301 HydrophobicContact CZ2-CG2 3.42Å; W297-V301 VanDerWaalsContact CZ2-CG2 3.42Å; W297-V301 HydrophobicContact CZ3-CG2 4.14Å; W297-V301 WeakPolarHBondContact O-CG2 3.4Å; W297-V301 PolarHBondContact O-N 3.19Å; E299-V301 PolarHBondContact O-N 2.98Å; V301-G303 PolarHBondContact O-N 2.95Å; V301-F304 PolarHBondContact O-N 3.12Å; V301-A306 HydrophobicContact CG1-CB 3.86Å; V301-L312 HydrophobicContact CB-CD2 4.32Å; V301-L312 HydrophobicContact CG1-CD2 4.43Å
302S96.3Very high97.1Very high65 Ų6539.5 Ų39.546%0.45523%0.234SC..Hα-helixtrans-56.9-35.9173.4-62.90000111.7S298 E299 A300 F304 G305 L312S298-S302 WeakPolarHBondContact O-CB 3.1Å; S298-S302 PolarHBondContact O-N 3.41Å; S298-S302 PolarHBondContact O-OG 3.1Å; E299-S302 WeakPolarHBondContact O-CB 3.48Å; E299-S302 PolarHBondContact O-N 2.65Å; A300-S302 VanDerWaalsContact C-N 3.31Å; A300-S302 PolarHBondContact O-N 2.85Å; S302-F304 PolarHBondContact O-N 3.37Å; S302-G305 PolarHBondContact O-N 3.39Å; S302-L312 WeakPolarHBondContact OG-CD2 3.4Å
303G95.3Very high97Very high71 Ų7140 Ų4073%0.73224%0.238SC*.THydrogen-bonded Turntrans-62.6-18.6177.600000114.8E299 A300 V301E299-G303 PolarHBondContact O-N 2.91Å; A300-G303 PolarHBondContact O-N 3.49Å; A300-G303 VanDerWaalsContact O-N 3.14Å; V301-G303 PolarHBondContact O-N 2.95Å
304F96.6Very high97Very high65 Ų6540.1 Ų40.129%0.28524%0.239SC..THydrogen-bonded Turntrans-91.52.5175.7-67.5-83.6000113.7I253 I256 K257 I260 I266 A300 V301 S302I253-F304 HydrophobicContact CG2-CE2 4.42Å; I253-F304 HydrophobicContact CG2-CZ 4.11Å; I256-F304 HydrophobicContact CB-CE2 4.5Å; I256-F304 HydrophobicContact CB-CZ 4.4Å; I256-F304 HydrophobicContact CD1-CE2 4.48Å; I256-F304 HydrophobicContact CG2-CD1 3.67Å; I256-F304 HydrophobicContact CG2-CD2 3.92Å; I256-F304 HydrophobicContact CG2-CE1 3.65Å; I256-F304 HydrophobicContact CG2-CE2 3.9Å; I256-F304 HydrophobicContact CG2-CG 3.8Å; I256-F304 HydrophobicContact CG2-CZ 3.76Å; K257-F304 HydrophobicContact CG-CE1 4.07Å; K257-F304 HydrophobicContact CG-CZ 4.12Å; I260-F304 HydrophobicContact CD1-CD1 3.67Å; I260-F304 HydrophobicContact CD1-CE1 4.26Å; I260-F304 HydrophobicContact CD1-CG 4.41Å; I266-F304 HydrophobicContact CD1-CB 4.36Å; I266-F304 HydrophobicContact CG1-CB 4.29Å; A300-F304 WeakPolarHBondContact O-CD2 3.4Å; V301-F304 PolarHBondContact O-N 3.12Å; S302-F304 PolarHBondContact O-N 3.37Å
305G95.1Very high97Very high42 Ų4242 Ų4243%0.43325%0.246SC..THydrogen-bonded Turntrans78.121.917600000115.1S302 Q307S302-G305 PolarHBondContact O-N 3.39Å; G305-Q307 PolarHBondContact O-N 2.9Å; G305-Q307 PolarHBondContact O-NE2 3.25Å
306A95.9Very high96.9Very high13 Ų1340.7 Ų40.711%0.10724%0.241CC..  trans-56.1134.9176.900000112.2I266 V301I266-A306 HydrophobicContact CG1-CB 3.97Å; I266-A306 HydrophobicContact CG2-CB 4.05Å; V301-A306 HydrophobicContact CG1-CB 3.86Å
307Q95Very high96.9Very high157 Ų15741.6 Ų41.673%0.73425%0.245SC*.  trans-108.9-24.5-179.7-58-59.5-56.800112.5D267 G305 P309D267-Q307 PolarHBondContact OD1-N 3.38Å; D267-Q307 PolarHBondContact OD2-N 3.12Å; G305-Q307 PolarHBondContact O-N 2.9Å; G305-Q307 PolarHBondContact O-NE2 3.25Å; Q307-P309 WeakPolarHBondContact O-CD 3.41Å
308D95.2Very high96.9Very high49 Ų4941.4 Ų41.426%0.26224%0.244SC..SBendtrans-80.2121173-172.7-16.4000109.5D267 K310 S311D267-D308 HydrophobicContact CB-CB 4.33Å; D267-D308 PolarHBondContact OD1-N 3.21Å; D267-D308 VanDerWaalsContact OD1-N 3.14Å; D267-D308 PolarHBondContact OD2-N 3.09Å; D308-K310 PolarHBondContact O-N 3.21Å; D308-K310 WeakPolarHBondContact OD1-CB 3.4Å; D308-K310 WeakPolarHBondContact OD1-CG 3.31Å; D308-K310 PolarHBondContact OD1-N 3.38Å; D308-S311 VanDerWaalsContact O-CB 3.29Å; D308-S311 WeakPolarHBondContact O-CB 3.43Å; D308-S311 PolarHBondContact O-N 2.95Å; D308-S311 PolarHBondContact O-OG 2.85Å
309P95.3Very high96.9Very high74 Ų7441.9 Ų41.948%0.48125%0.246SC..Hα-helixtrans-50.7-28.6172.6-28.236.3000114Y59 Q307 S311 L312 A313Y59-P309 PolarHBondContact OH-O 3.01Å; Q307-P309 WeakPolarHBondContact O-CD 3.41Å; P309-S311 VanDerWaalsContact C-N 3.27Å; P309-S311 PolarHBondContact O-N 2.84Å; P309-L312 PolarHBondContact O-N 3.35Å; P309-A313 PolarHBondContact O-N 3.01Å
310K95.6Very high97Very high120 Ų12037.9 Ų37.952%0.52223%0.227SC..Hα-helixtrans-66.3-27.7177.7-64.4172.7-168.4156.20113.3P271 D308 L312 A313P271-K310 HydrophobicContact CB-CB 4.07Å; P271-K310 HydrophobicContact CG-CB 4.26Å; D308-K310 PolarHBondContact O-N 3.21Å; D308-K310 WeakPolarHBondContact OD1-CB 3.4Å; D308-K310 WeakPolarHBondContact OD1-CG 3.31Å; D308-K310 PolarHBondContact OD1-N 3.38Å; K310-L312 VanDerWaalsContact C-N 3.26Å; K310-L312 PolarHBondContact O-N 3.16Å; K310-A313 PolarHBondContact O-N 3.46Å
311S97.5Very high97.1Very high1 Ų137.1 Ų37.11%0.00722%0.22CC..Hα-helixtrans-66.6-32.5177.4-59.60000111.5D267 D308 P309D267-S311 WeakPolarHBondContact OD1-CB 3.4Å; D267-S311 PolarHBondContact OD1-OG 2.88Å; D308-S311 VanDerWaalsContact O-CB 3.29Å; D308-S311 WeakPolarHBondContact O-CB 3.43Å; D308-S311 PolarHBondContact O-N 2.95Å; D308-S311 PolarHBondContact O-OG 2.85Å; P309-S311 VanDerWaalsContact C-N 3.27Å; P309-S311 PolarHBondContact O-N 2.84Å
312L98.1Very high97Very high18 Ų1837.6 Ų37.69%0.09423%0.226CC..Hα-helixtrans-81-17.1-179.3-65.5145.1000113.2Y59 S298 V301 S302 P309 K310 L314Y59-L312 HydrophobicContact CE2-CB 3.72Å; S298-L312 VanDerWaalsContact O-CD2 3.26Å; S298-L312 WeakPolarHBondContact O-CD2 3.42Å; V301-L312 HydrophobicContact CB-CD2 4.32Å; V301-L312 HydrophobicContact CG1-CD2 4.43Å; S302-L312 WeakPolarHBondContact OG-CD2 3.4Å; P309-L312 PolarHBondContact O-N 3.35Å; K310-L312 VanDerWaalsContact C-N 3.26Å; K310-L312 PolarHBondContact O-N 3.16Å; L312-L314 PolarHBondContact O-N 2.84Å
313A97.8Very high97Very high12 Ų1239.3 Ų39.310%0.09922%0.222CC..  trans-84114.2-176.100000112.1Y59 P63 P309 K310 R315Y59-A313 HydrophobicContact CD2-CB 4.39Å; Y59-A313 HydrophobicContact CE1-CB 4.26Å; Y59-A313 HydrophobicContact CE2-CB 4.16Å; P63-A313 HydrophobicContact CB-CB 4.12Å; P309-A313 PolarHBondContact O-N 3.01Å; K310-A313 PolarHBondContact O-N 3.46Å; A313-R315 PolarHBondContact O-N 3.04Å
314L98.6Very high97.1Very high1 Ų136.6 Ų36.61%0.00519%0.192CC..  trans-73.1118.5168.7-177.6151.4000109.9L249 F275 F277 A293 R294 W297 L312 T316L249-L314 HydrophobicContact CD2-CD1 3.93Å; F275-L314 HydrophobicContact CB-CD1 4.48Å; F275-L314 HydrophobicContact CB-CD2 4.2Å; F275-L314 HydrophobicContact CB-CG 4.21Å; F275-L314 HydrophobicContact CD1-CD1 3.9Å; F275-L314 HydrophobicContact CD1-CG 4.38Å; F275-L314 HydrophobicContact CD2-CB 4.39Å; F275-L314 HydrophobicContact CD2-CD1 3.82Å; F275-L314 HydrophobicContact CD2-CD2 4.32Å; F275-L314 HydrophobicContact CD2-CG 3.47Å; F275-L314 VanDerWaalsContact CD2-CG 3.47Å; F275-L314 HydrophobicContact CE1-CD1 4.04Å; F275-L314 HydrophobicContact CE2-CB 4.45Å; F275-L314 HydrophobicContact CE2-CD1 3.93Å; F275-L314 HydrophobicContact CE2-CG 3.85Å; F275-L314 HydrophobicContact CG-CD1 3.78Å; F275-L314 HydrophobicContact CG-CD2 4.27Å; F275-L314 HydrophobicContact CG-CG 3.75Å; F275-L314 HydrophobicContact CZ-CD1 4.04Å; F275-L314 HydrophobicContact CZ-CG 4.46Å; F277-L314 HydrophobicContact CE2-CD1 4.37Å; F277-L314 HydrophobicContact CE2-CD2 4.32Å; A293-L314 HydrophobicContact CB-CD1 4.12Å; R294-L314 HydrophobicContact CG-CB 4.1Å; R294-L314 HydrophobicContact CG-CD2 4.03Å; W297-L314 HydrophobicContact CB-CB 3.98Å; W297-L314 HydrophobicContact CB-CD1 3.74Å; W297-L314 HydrophobicContact CB-CG 4.48Å; W297-L314 HydrophobicContact CG-CB 3.89Å; W297-L314 HydrophobicContact CG-CD1 4.04Å; W297-L314 HydrophobicContact CG-CG 4.46Å; L312-L314 PolarHBondContact O-N 2.84Å; L314-T316 HydrophobicContact CD2-CG2 4.39Å
315R98Very high97.2Very high41 Ų4134 Ų3416%0.15518%0.181CC..  trans-111.7122.2175.9-59.7173.3-64.1133.99.9108.4N225 P271 R272 L273 S274 F275 A313N225-R315 PolarHBondContact OD1-NH1 3.18Å; N225-R315 PolarHBondContact OD1-NH2 2.98Å; N225-R315 VanDerWaalsContact OD1-NH2 3.13Å; P271-R315 VanDerWaalsContact O-CZ 3.22Å; P271-R315 PolarHBondContact O-NH2 3.04Å; R272-R315 VanDerWaalsContact C-NH2 3.32Å; L273-R315 PolarHBondContact O-NH2 2.98Å; S274-R315 CarbonylContact C-O 3.42Å; S274-R315 WeakPolarHBondContact CA-O 3.46Å; F275-R315 PolarHBondContact N-O 3.39Å; A313-R315 PolarHBondContact O-N 3.04Å
316T98.4Very high97.2Very high3 Ų332.5 Ų32.52%0.01816%0.163CC..EExtended strand (participates in β ladder)trans-124.2141.7-170.6-159.70000114.1F275 F277 L290 L314 T349 Q350 S351F275-T316 CarbonylContact O-C 3.56Å; F275-T316 VanDerWaalsContact O-CA 3.29Å; F275-T316 WeakPolarHBondContact O-CA 3.41Å; F275-T316 PolarHBondContact O-OG1 3.4Å; F277-T316 WeakPolarHBondContact CD2-OG1 3.06Å; L290-T316 HydrophobicContact CD2-CG2 4.3Å; L314-T316 HydrophobicContact CD2-CG2 4.39Å; T316-T349 PolarHBondContact O-OG1 3.5Å; T316-Q350 WeakPolarHBondContact O-CB 3.02Å; T316-Q350 PolarHBondContact O-N 3.43Å; T316-S351 PolarHBondContact O-N 3.28Å
317H98.2Very high97.2Very high24 Ų2433.1 Ų33.111%0.11116%0.164CC..EExtended strand (participates in β ladder)trans-82.4154.2152.5-175.458.5000109.2F275 F276 F277 S351 H353F275-H317 PolarHBondContact O-N 2.91Å; F276-H317 WeakPolarHBondContact CA-O 3.11Å; F276-H317 HydrophobicContact CB-CB 4.48Å; F276-H317 HydrophobicContact CD2-CB 4.15Å; F276-H317 AromaticContact CD2-CD2 3.45Å; F276-H317 VanDerWaalsContact CD2-CD2 3.45Å; F276-H317 WeakPolarHBondContact CD2-CD2 3.48Å; F276-H317 AromaticContact CE2-CD2 3.46Å; F276-H317 VanDerWaalsContact CE2-CD2 3.46Å; F276-H317 WeakPolarHBondContact CE2-CD2 3.25Å; F277-H317 PolarHBondContact N-O 3.28Å; F277-H317 VanDerWaalsContact N-O 3.16Å; H317-S351 CarbonylContact C-O 3.49Å; H317-S351 WeakPolarHBondContact CA-O 3.26Å; H317-S351 PolarHBondContact ND1-O 3.39Å; H317-S351 PolarHBondContact ND1-OG 2.81Å; H317-H353 PolarHBondContact CE1-N 2.74Å
318C98.7Very high97.2Very high0 Ų027.5 Ų27.50%014%0.138CC..EExtended strand (participates in β ladder)trans-131148.6168.3-70.20000109.2F277 I279 A344 T349 S351 L352 H353F277-C318 WeakPolarHBondContact O-CA 3.37Å; I279-C318 HydrophobicContact CD1-CB 4.41Å; I279-C318 HydrophobicContact CG1-CB 3.8Å; C318-A344 HydrophobicContact CB-CB 3.97Å; C318-T349 PolarHBondContact SG-OG1 3.07Å; C318-T349 VanDerWaalsContact SG-OG1 3.32Å; C318-S351 PolarHBondContact N-O 2.92Å; C318-L352 HydrophobicContact CB-CD1 3.92Å; C318-L352 CarbonylContact O-C 3.44Å; C318-L352 WeakPolarHBondContact O-CA 3.37Å; C318-L352 WeakPolarHBondContact O-CD1 3.38Å; C318-H353 PolarHBondContact O-N 3.28Å
319Q98.6Very high97.2Very high14 Ų1427.2 Ų27.27%0.06514%0.136CC..EExtended strand (participates in β ladder)trans-128.8136.6168.6177.5165.3-100107.9Y232 F276 F277 G278 I279 H353 N355Y232-Q319 HydrophobicContact CD2-CB 3.81Å; Y232-Q319 HydrophobicContact CD2-CG 4.13Å; Y232-Q319 HydrophobicContact CE2-CB 3.79Å; Y232-Q319 HydrophobicContact CE2-CG 3.57Å; Y232-Q319 PolarHBondContact OH-NE2 2.64Å; F276-Q319 HydrophobicContact CE2-CB 3.42Å; F276-Q319 VanDerWaalsContact CE2-CB 3.42Å; F276-Q319 HydrophobicContact CZ-CB 3.67Å; F277-Q319 PolarHBondContact O-N 2.79Å; F277-Q319 VanDerWaalsContact O-N 3.15Å; G278-Q319 WeakPolarHBondContact CA-O 2.96Å; I279-Q319 PolarHBondContact N-O 3.11Å; Q319-H353 WeakPolarHBondContact CA-O 3.46Å; Q319-H353 HydrophobicContact CB-CB 3.99Å; Q319-H353 HydrophobicContact CG-CB 3.92Å; Q319-H353 PolarHBondContact NE2-CD2 3.05Å; Q319-N355 PolarHBondContact NE2-OD1 3.37Å
320T98.8Very high97.2Very high0 Ų024 Ų240%012%0.116CC..EExtended strand (participates in β ladder)trans-60.4147.1170.355.70000109.8I279 G322 T337 E340 H353 T354 N355I279-T320 CarbonylContact O-C 3.45Å; T320-G322 PolarHBondContact O-N 3.33Å; T320-T337 HydrophobicContact CG2-CG2 3.97Å; T320-E340 WeakPolarHBondContact CB-OE2 3.42Å; T320-E340 HydrophobicContact CG2-CB 3.61Å; T320-H353 PolarHBondContact N-O 3.36Å; T320-T354 HydrophobicContact CG2-CG2 4.09Å; T320-N355 PolarHBondContact O-ND2 3.48Å; T320-N355 PolarHBondContact OG1-N 2.91Å; T320-N355 PolarHBondContact OG1-ND2 2.84Å; T320-N355 PolarHBondContact OG1-OD1 2.83Å
321S98.3Very high97.3Very high9 Ų924.3 Ų24.36%0.06311%0.114CC..  trans-66.5130.4-174.5-176.60000110.6E236 I279 S324 N355E236-S321 VanDerWaalsContact OE1-CA 3.26Å; E236-S321 WeakPolarHBondContact OE1-CA 3.4Å; E236-S321 WeakPolarHBondContact OE1-CB 3.11Å; E236-S321 PolarHBondContact OE1-OG 2.94Å; I279-S321 PolarHBondContact O-N 2.91Å; S321-S324 PolarHBondContact O-OG 3.4Å; S321-S324 VanDerWaalsContact O-OG 3.05Å; S321-S324 PolarHBondContact OG-N 2.93Å; S321-N355 PolarHBondContact O-ND2 3.27Å
322G95.8Very high97.3Very high11 Ų1125.9 Ų25.911%0.11312%0.123CC..SBendtrans-74.7-39.517300000110.2E236 T320 S324 L325 N355E236-G322 PolarHBondContact OE1-N 3.38Å; E236-G322 VanDerWaalsContact OE2-CA 3.3Å; E236-G322 WeakPolarHBondContact OE2-CA 3.39Å; E236-G322 PolarHBondContact OE2-N 3.34Å; T320-G322 PolarHBondContact O-N 3.33Å; G322-S324 VanDerWaalsContact C-N 3.25Å; G322-S324 PolarHBondContact O-N 3.01Å; G322-L325 WeakPolarHBondContact O-CB 3.36Å; G322-L325 PolarHBondContact O-N 2.61Å; G322-L325 VanDerWaalsContact O-N 3.08Å; G322-N355 WeakPolarHBondContact CA-ND2 3.49Å; G322-N355 PolarHBondContact N-ND2 3.15Å
323W96.6Very high97.3Very high100 Ų10025 Ų2538%0.37912%0.118SC..THydrogen-bonded Turntrans-61.3-26.8177.5176.378000114.4E236 L325 E442 I446 R599E236-W323 PolarHBondContact OE2-N 3.17Å; W323-L325 PolarHBondContact O-N 3.5Å; W323-E442 HydrophobicContact CH2-CG 3.84Å; W323-E442 HydrophobicContact CZ2-CG 4.33Å; W323-I446 HydrophobicContact CH2-CD1 3.79Å; W323-I446 HydrophobicContact CZ2-CD1 3.59Å; W323-R599 VanDerWaalsContact CD1-CZ 3.5Å; W323-R599 VanDerWaalsContact CE2-CZ 3.4Å
324S97.8Very high97.4Very high14 Ų1426.4 Ų26.410%0.09813%0.126CC..THydrogen-bonded Turntrans-73.7-14.2177.271.90000113.4S321 G322 R336 E340S321-S324 PolarHBondContact O-OG 3.4Å; S321-S324 VanDerWaalsContact O-OG 3.05Å; S321-S324 PolarHBondContact OG-N 2.93Å; G322-S324 VanDerWaalsContact C-N 3.25Å; G322-S324 PolarHBondContact O-N 3.01Å; S324-R336 VanDerWaalsContact O-CD 3.23Å; S324-R336 WeakPolarHBondContact O-CD 3.47Å; S324-E340 VanDerWaalsContact CB-OE1 3.26Å; S324-E340 WeakPolarHBondContact CB-OE1 3.39Å; S324-E340 PolarHBondContact OG-OE1 3.18Å
325L97.6Very high97.4Very high11 Ų1131.3 Ų31.36%0.05815%0.151CC..  trans-87.9142.2-176.6-53.2-169.1000111.1G322 W323 N333 R336 N355 A356 E359G322-L325 WeakPolarHBondContact O-CB 3.36Å; G322-L325 PolarHBondContact O-N 2.61Å; G322-L325 VanDerWaalsContact O-N 3.08Å; W323-L325 PolarHBondContact O-N 3.5Å; L325-N333 WeakPolarHBondContact CA-OD1 3.33Å; L325-N333 HydrophobicContact CB-CB 4.42Å; L325-N333 HydrophobicContact CD1-CB 4.5Å; L325-N333 HydrophobicContact CD2-CB 3.88Å; L325-N333 HydrophobicContact CG-CB 4.48Å; L325-R336 HydrophobicContact CD2-CB 4Å; L325-N355 HydrophobicContact CD1-CB 3.54Å; L325-A356 WeakPolarHBondContact CD1-O 3.41Å; L325-E359 HydrophobicContact CB-CB 4.36Å; L325-E359 HydrophobicContact CD1-CB 3.53Å; L325-E359 HydrophobicContact CD1-CG 4.04Å
326T96.6Very high97.4Very high10 Ų1030.4 Ų30.46%0.06115%0.147CC..  trans-110.3144.6-170.5600000111.6Q328 N333 R336 I453 V456T326-Q328 WeakPolarHBondContact CB-O 3.48Å; T326-Q328 PolarHBondContact OG1-O 3.2Å; T326-N333 PolarHBondContact N-ND2 2.89Å; T326-N333 PolarHBondContact N-OD1 3.09Å; T326-N333 PolarHBondContact O-ND2 3.49Å; T326-N333 PolarHBondContact OG1-OD1 3.07Å; T326-R336 PolarHBondContact OG1-NH1 3.27Å; T326-I453 HydrophobicContact CG2-CG2 3.58Å; T326-V456 HydrophobicContact CG2-CG2 3.52Å
327E94.1Very high97.4Very high27 Ų2730.4 Ų30.413%0.12615%0.147CC..SBendtrans-67-43.5168.8-175.8-170.1170.400110.2A360 L361 P677 P694E327-A360 HydrophobicContact CB-CB 4.35Å; E327-L361 HydrophobicContact CG-CD2 3.56Å; E327-L361 HydrophobicContact CG-CG 4.34Å; E327-P677 WeakPolarHBondContact OE1-CG 3.32Å; E327-P694 HydrophobicContact CB-CB 4.13Å; E327-P694 HydrophobicContact CB-CG 4.41Å; E327-P694 WeakPolarHBondContact OE2-CD 3.47Å
328Q95.1Very high97.5Very high39 Ų3931.4 Ų31.418%0.18216%0.155CC..SBendtrans-75.4140.7179.5-58.479.412.500111.4T326 V456 E464 P694T326-Q328 WeakPolarHBondContact CB-O 3.48Å; T326-Q328 PolarHBondContact OG1-O 3.2Å; Q328-V456 HydrophobicContact CB-CG2 4.4Å; Q328-E464 WeakPolarHBondContact CB-OE1 3.38Å; Q328-P694 PolarHBondContact NE2-O 3.01Å
329D95.9Very high97.5Very high42 Ų4234 Ų3423%0.22517%0.169CC..SBendtrans40.760.1-177.6-167.80.8000111.8Y331 N332 L461 E464D329-Y331 PolarHBondContact O-N 3.2Å; D329-Y331 VanDerWaalsContact O-N 3.12Å; D329-N332 WeakPolarHBondContact CB-ND2 3.26Å; D329-N332 VanDerWaalsContact O-CB 3.31Å; D329-N332 WeakPolarHBondContact O-CB 3.46Å; D329-N332 PolarHBondContact O-N 3.1Å; D329-N332 PolarHBondContact O-ND2 2.94Å; D329-N332 PolarHBondContact OD2-ND2 2.98Å; D329-L461 HydrophobicContact CB-CD1 4.03Å; D329-E464 PolarHBondContact N-OE2 3.07Å
330P95.6Very high97.5Very high8 Ų833.4 Ų33.45%0.05217%0.166CC..THydrogen-bonded Turntrans-68.5-17.5-162.727.9-36.2000112.8N332 N333 F357 L361P330-N332 PolarHBondContact O-N 3.43Å; P330-N333 WeakPolarHBondContact O-CB 3.41Å; P330-N333 PolarHBondContact O-N 2.71Å; P330-N333 PolarHBondContact O-ND2 2.97Å; P330-F357 HydrophobicContact CB-CD2 4.25Å; P330-L361 HydrophobicContact CB-CD1 4.3Å; P330-L361 HydrophobicContact CG-CD1 4.32Å
331Y97.2Very high97.5Very high125 Ų12533.4 Ų33.449%0.4917%0.166SC..THydrogen-bonded Turntrans-64.5-23.6173.1-76-79.2000113.1D329 N333 V334 F357 F367D329-Y331 PolarHBondContact O-N 3.2Å; D329-Y331 VanDerWaalsContact O-N 3.12Å; Y331-N333 PolarHBondContact O-N 3.2Å; Y331-V334 WeakPolarHBondContact O-CB 3.46Å; Y331-V334 WeakPolarHBondContact O-CG2 3.37Å; Y331-V334 PolarHBondContact O-N 3.31Å; Y331-V334 VanDerWaalsContact O-N 3.09Å; Y331-F357 HydrophobicContact CE1-CE2 4.31Å; Y331-F357 HydrophobicContact CE1-CZ 4.27Å; Y331-F367 HydrophobicContact CE1-CE1 4.47Å
332N98.1Very high97.5Very high35 Ų3535.5 Ų35.519%0.18718%0.176CC..Hα-helixtrans-59.3-26.8169.7-72.8-40.5000112.3D329 P330 V334 I335 R336D329-N332 WeakPolarHBondContact CB-ND2 3.26Å; D329-N332 VanDerWaalsContact O-CB 3.31Å; D329-N332 WeakPolarHBondContact O-CB 3.46Å; D329-N332 PolarHBondContact O-N 3.1Å; D329-N332 PolarHBondContact O-ND2 2.94Å; D329-N332 PolarHBondContact OD2-ND2 2.98Å; P330-N332 PolarHBondContact O-N 3.43Å; N332-V334 PolarHBondContact O-N 3.35Å; N332-I335 WeakPolarHBondContact O-CB 3.39Å; N332-I335 PolarHBondContact O-N 2.52Å; N332-R336 VanDerWaalsContact CB-NH1 3.34Å; N332-R336 PolarHBondContact O-N 3.2Å; N332-R336 VanDerWaalsContact O-N 3.08Å
333N98.4Very high97.7Very high0 Ų035 Ų350%017%0.17CC..Hα-helixtrans-62.9-27.1177.2-62.5-30.1000112.3L325 T326 P330 Y331 I335 R336 T337 F357L325-N333 WeakPolarHBondContact CA-OD1 3.33Å; L325-N333 HydrophobicContact CB-CB 4.42Å; L325-N333 HydrophobicContact CD1-CB 4.5Å; L325-N333 HydrophobicContact CD2-CB 3.88Å; L325-N333 HydrophobicContact CG-CB 4.48Å; T326-N333 PolarHBondContact N-ND2 2.89Å; T326-N333 PolarHBondContact N-OD1 3.09Å; T326-N333 PolarHBondContact O-ND2 3.49Å; T326-N333 PolarHBondContact OG1-OD1 3.07Å; P330-N333 WeakPolarHBondContact O-CB 3.41Å; P330-N333 PolarHBondContact O-N 2.71Å; P330-N333 PolarHBondContact O-ND2 2.97Å; Y331-N333 PolarHBondContact O-N 3.2Å; N333-I335 VanDerWaalsContact C-N 3.26Å; N333-I335 PolarHBondContact O-N 3.26Å; N333-R336 PolarHBondContact O-N 3.13Å; N333-R336 PolarHBondContact OD1-NH1 3.34Å; N333-T337 WeakPolarHBondContact O-CB 3.26Å; N333-T337 PolarHBondContact O-N 3.12Å; N333-T337 PolarHBondContact O-OG1 3.31Å; N333-T337 VanDerWaalsContact O-OG1 3.07Å; N333-F357 HydrophobicContact CB-CB 3.96Å; N333-F357 PolarHBondContact ND2-O 3Å
334V98.6Very high97.8Very high41 Ų4130.2 Ų30.225%0.24815%0.152CC..Hα-helixtrans-59-41.3172.1-179.60000110.8Y331 N332 T338 F357 I371Y331-V334 WeakPolarHBondContact O-CB 3.46Å; Y331-V334 WeakPolarHBondContact O-CG2 3.37Å; Y331-V334 PolarHBondContact O-N 3.31Å; Y331-V334 VanDerWaalsContact O-N 3.09Å; N332-V334 PolarHBondContact O-N 3.35Å; V334-T338 WeakPolarHBondContact O-CB 3.48Å; V334-T338 PolarHBondContact O-N 3.13Å; V334-T338 VanDerWaalsContact O-N 3.15Å; V334-T338 PolarHBondContact O-OG1 3.01Å; V334-F357 HydrophobicContact CG2-CB 3.77Å; V334-F357 HydrophobicContact CG2-CD1 4.4Å; V334-F357 HydrophobicContact CG2-CG 4.25Å; V334-I371 HydrophobicContact CG1-CG2 3.99Å; V334-I371 HydrophobicContact CG2-CG2 4.04Å
335I98.7Very high97.8Very high104 Ų10429.7 Ų29.753%0.53315%0.149SC..Hα-helixtrans-72.8-43.5179.4-58.4169.2000110.2N332 N333 T338 I339N332-I335 WeakPolarHBondContact O-CB 3.39Å; N332-I335 PolarHBondContact O-N 2.52Å; N333-I335 VanDerWaalsContact C-N 3.26Å; N333-I335 PolarHBondContact O-N 3.26Å; I335-T338 WeakPolarHBondContact O-CB 3.39Å; I335-T338 PolarHBondContact O-N 3.18Å; I335-I339 HydrophobicContact CG2-CD1 4.08Å; I335-I339 WeakPolarHBondContact O-CG1 3.25Å; I335-I339 PolarHBondContact O-N 3.4Å
336R98.8Very high97.9Very high22 Ų2230.6 Ų30.68%0.08315%0.153CC..Hα-helixtrans-57-56.5177-65.4-175.3-179102.4-0.3111.5M281 S324 L325 T326 N332 N333 T338 I339 E340 V454M281-R336 HydrophobicContact CE-CB 4.4Å; M281-R336 HydrophobicContact CE-CG 4.14Å; M281-R336 HydrophobicContact SD-CB 3.58Å; M281-R336 VanDerWaalsContact SD-CB 3.58Å; M281-R336 HydrophobicContact SD-CG 3.76Å; S324-R336 VanDerWaalsContact O-CD 3.23Å; S324-R336 WeakPolarHBondContact O-CD 3.47Å; L325-R336 HydrophobicContact CD2-CB 4Å; T326-R336 PolarHBondContact OG1-NH1 3.27Å; N332-R336 VanDerWaalsContact CB-NH1 3.34Å; N332-R336 PolarHBondContact O-N 3.2Å; N332-R336 VanDerWaalsContact O-N 3.08Å; N333-R336 PolarHBondContact O-N 3.13Å; N333-R336 PolarHBondContact OD1-NH1 3.34Å; R336-T338 PolarHBondContact O-N 2.72Å; R336-I339 WeakPolarHBondContact O-CB 3.26Å; R336-I339 PolarHBondContact O-N 2.7Å; R336-E340 WeakPolarHBondContact O-CG 3.25Å; R336-E340 PolarHBondContact O-N 2.92Å; R336-V454 PolarHBondContact NH2-O 3.06Å
337T98.9Very high98Very high2 Ų230.1 Ų30.11%0.01215%0.15CC..Hα-helixtrans-58.1-33.6177.7-59.70000111.9T320 N333 A341 T354 N355T320-T337 HydrophobicContact CG2-CG2 3.97Å; N333-T337 WeakPolarHBondContact O-CB 3.26Å; N333-T337 PolarHBondContact O-N 3.12Å; N333-T337 PolarHBondContact O-OG1 3.31Å; N333-T337 VanDerWaalsContact O-OG1 3.07Å; T337-A341 WeakPolarHBondContact O-CB 3.47Å; T337-A341 PolarHBondContact O-N 2.72Å; T337-T354 HydrophobicContact CG2-CG2 3.83Å; T337-N355 WeakPolarHBondContact CG2-O 3.49Å
338T98.8Very high98.2Very high46 Ų4629.1 Ų29.128%0.28215%0.148SC..Hα-helixtrans-66.4-44.5175.5-60.50000112V334 I335 R336 E340 A341 L342 T375V334-T338 WeakPolarHBondContact O-CB 3.48Å; V334-T338 PolarHBondContact O-N 3.13Å; V334-T338 VanDerWaalsContact O-N 3.15Å; V334-T338 PolarHBondContact O-OG1 3.01Å; I335-T338 WeakPolarHBondContact O-CB 3.39Å; I335-T338 PolarHBondContact O-N 3.18Å; R336-T338 PolarHBondContact O-N 2.72Å; T338-E340 VanDerWaalsContact C-N 3.34Å; T338-A341 PolarHBondContact O-N 3.01Å; T338-L342 WeakPolarHBondContact O-CG 3.28Å; T338-L342 PolarHBondContact O-N 3.17Å; T338-T375 HydrophobicContact CG2-CG2 4.4Å
339I98.8Very high98.3Very high55 Ų5527.3 Ų27.328%0.28214%0.139SC..Hα-helixtrans-63.7-42.2176.9-68.9167.7000110.6M281 L283 I335 R336 L342 A343M281-I339 HydrophobicContact CE-CB 4.48Å; M281-I339 HydrophobicContact CE-CD1 4.02Å; M281-I339 HydrophobicContact CE-CG2 4.35Å; L283-I339 HydrophobicContact CB-CG2 4.23Å; L283-I339 HydrophobicContact CD1-CG2 4.12Å; I335-I339 HydrophobicContact CG2-CD1 4.08Å; I335-I339 WeakPolarHBondContact O-CG1 3.25Å; I335-I339 PolarHBondContact O-N 3.4Å; R336-I339 WeakPolarHBondContact O-CB 3.26Å; R336-I339 PolarHBondContact O-N 2.7Å; I339-L342 WeakPolarHBondContact O-CB 3.24Å; I339-L342 PolarHBondContact O-N 3.17Å; I339-A343 PolarHBondContact O-N 3.24Å
340E98.9Very high98.4Very high0 Ų027.5 Ų27.50%014%0.139CC..Hα-helixtrans-66.7-41.6177.5-66.8170.4153.900111.6I279 M281 T320 S324 R336 T338 L342 A343 A344I279-E340 HydrophobicContact CG2-CB 4.14Å; I279-E340 WeakPolarHBondContact CG2-O 3.43Å; I279-E340 WeakPolarHBondContact O-CG 3.36Å; M281-E340 HydrophobicContact SD-CG 4.12Å; T320-E340 WeakPolarHBondContact CB-OE2 3.42Å; T320-E340 HydrophobicContact CG2-CB 3.61Å; S324-E340 VanDerWaalsContact CB-OE1 3.26Å; S324-E340 WeakPolarHBondContact CB-OE1 3.39Å; S324-E340 PolarHBondContact OG-OE1 3.18Å; R336-E340 WeakPolarHBondContact O-CG 3.25Å; R336-E340 PolarHBondContact O-N 2.92Å; T338-E340 VanDerWaalsContact C-N 3.34Å; E340-L342 VanDerWaalsContact C-N 3.3Å; E340-L342 PolarHBondContact O-N 3.49Å; E340-A343 WeakPolarHBondContact O-CB 3.3Å; E340-A343 PolarHBondContact O-N 3.44Å; E340-A343 VanDerWaalsContact O-N 3.15Å; E340-A344 PolarHBondContact O-N 3.24Å
341A98.9Very high98.5Very high0 Ų027.8 Ų27.80%014%0.141CC..Hα-helixtrans-61.5-38.4173.400000112.1T337 T338 A344 T345 L352 T354 T375 I379T337-A341 WeakPolarHBondContact O-CB 3.47Å; T337-A341 PolarHBondContact O-N 2.72Å; T338-A341 PolarHBondContact O-N 3.01Å; A341-A344 PolarHBondContact O-N 2.89Å; A341-T345 WeakPolarHBondContact O-CB 3.41Å; A341-T345 VanDerWaalsContact O-CG2 3.25Å; A341-T345 WeakPolarHBondContact O-CG2 3.23Å; A341-T345 PolarHBondContact O-N 3.43Å; A341-T345 PolarHBondContact O-OG1 3.05Å; A341-L352 HydrophobicContact CB-CD2 3.96Å; A341-T354 HydrophobicContact CB-CG2 3.84Å; A341-T375 HydrophobicContact CB-CG2 4.17Å; A341-I379 HydrophobicContact CB-CD1 3.59Å
342L98.6Very high98.5Very high53 Ų5321.9 Ų21.928%0.27712%0.118SC..Hα-helixtrans-63.3-43.3172.6-72.5171.1000111.5L283 T338 I339 E340 T345 L346 I379 L385L283-L342 HydrophobicContact CD1-CB 4.37Å; T338-L342 WeakPolarHBondContact O-CG 3.28Å; T338-L342 PolarHBondContact O-N 3.17Å; I339-L342 WeakPolarHBondContact O-CB 3.24Å; I339-L342 PolarHBondContact O-N 3.17Å; E340-L342 VanDerWaalsContact C-N 3.3Å; E340-L342 PolarHBondContact O-N 3.49Å; L342-T345 WeakPolarHBondContact CA-OG1 3.35Å; L342-T345 PolarHBondContact O-N 2.65Å; L342-T345 PolarHBondContact O-OG1 3.42Å; L342-T345 VanDerWaalsContact O-OG1 3.09Å; L342-L346 VanDerWaalsContact O-CB 3.22Å; L342-L346 WeakPolarHBondContact O-CB 3.49Å; L342-L346 WeakPolarHBondContact O-CD1 3.37Å; L342-L346 WeakPolarHBondContact O-CG 3.46Å; L342-L346 PolarHBondContact O-N 3.25Å; L342-I379 HydrophobicContact CD2-CD1 4.19Å; L342-I379 HydrophobicContact CD2-CG1 4.2Å; L342-I379 HydrophobicContact CD2-CG2 4.18Å; L342-I379 HydrophobicContact CG-CD1 4.31Å; L342-L385 HydrophobicContact CD2-CD1 4.2Å
343A98.8Very high98.5Very high0 Ų020.7 Ų20.70%011%0.111CC..Hα-helixtrans-60.7-45.7174.900000112.5I279 L283 N286 V287 I339 E340 T345 G347I279-A343 HydrophobicContact CG2-CB 3.66Å; L283-A343 HydrophobicContact CG-CB 4.19Å; N286-A343 HydrophobicContact CB-CB 3.95Å; V287-A343 HydrophobicContact CG2-CB 4.41Å; V287-A343 WeakPolarHBondContact CG2-O 3.37Å; I339-A343 PolarHBondContact O-N 3.24Å; E340-A343 WeakPolarHBondContact O-CB 3.3Å; E340-A343 PolarHBondContact O-N 3.44Å; E340-A343 VanDerWaalsContact O-N 3.15Å; A343-T345 VanDerWaalsContact C-N 3.34Å; A343-T345 PolarHBondContact O-N 3.32Å; A343-G347 PolarHBondContact O-N 2.94Å
344A98.9Very high98.5Very high0 Ų020.7 Ų20.70%011%0.111CC..Hα-helixtrans-60.9-42.5179.300000112.4I279 C318 E340 A341 G348 T349 L352I279-A344 HydrophobicContact CG1-CB 3.92Å; I279-A344 HydrophobicContact CG2-CB 4.38Å; C318-A344 HydrophobicContact CB-CB 3.97Å; E340-A344 PolarHBondContact O-N 3.24Å; A341-A344 PolarHBondContact O-N 2.89Å; A344-G348 PolarHBondContact O-N 3.11Å; A344-T349 HydrophobicContact CB-CG2 4.26Å; A344-T349 WeakPolarHBondContact O-CB 3.27Å; A344-T349 WeakPolarHBondContact O-CG2 3.39Å; A344-T349 PolarHBondContact O-N 3.25Å; A344-T349 VanDerWaalsContact O-N 3.16Å; A344-L352 HydrophobicContact CB-CD1 3.68Å; A344-L352 HydrophobicContact CB-CD2 4.31Å
345T98.7Very high98.5Very high3 Ų318.8 Ų18.82%0.01810%0.1CC..Hα-helixtrans-76.3-45.5-178.253.60000111.4Y68 W73 A341 L342 A343 G347 G348 L352Y68-T345 VanDerWaalsContact CE2-O 3.26Å; Y68-T345 WeakPolarHBondContact CE2-O 3.41Å; Y68-T345 PolarHBondContact OH-O 2.59Å; W73-T345 HydrophobicContact CD2-CG2 3.77Å; W73-T345 HydrophobicContact CE3-CG2 3.67Å; W73-T345 HydrophobicContact CH2-CG2 3.44Å; W73-T345 VanDerWaalsContact CH2-CG2 3.44Å; W73-T345 HydrophobicContact CZ2-CG2 3.5Å; W73-T345 HydrophobicContact CZ3-CG2 3.52Å; A341-T345 WeakPolarHBondContact O-CB 3.41Å; A341-T345 VanDerWaalsContact O-CG2 3.25Å; A341-T345 WeakPolarHBondContact O-CG2 3.23Å; A341-T345 PolarHBondContact O-N 3.43Å; A341-T345 PolarHBondContact O-OG1 3.05Å; L342-T345 WeakPolarHBondContact CA-OG1 3.35Å; L342-T345 PolarHBondContact O-N 2.65Å; L342-T345 PolarHBondContact O-OG1 3.42Å; L342-T345 VanDerWaalsContact O-OG1 3.09Å; A343-T345 VanDerWaalsContact C-N 3.34Å; A343-T345 PolarHBondContact O-N 3.32Å; T345-G347 PolarHBondContact O-N 3.25Å; T345-G348 PolarHBondContact O-N 3.39Å; T345-L352 HydrophobicContact CG2-CD2 4.13Å
346L98.6Very high98.4Very high30 Ų3014 Ų1416%0.1578%0.075CC..Hα-helixtrans-60.3-32.3172.5-70.1169.3000112.3L283 V287 L342 G348 L385 P391 L392L283-L346 HydrophobicContact CD2-CD1 4.42Å; V287-L346 HydrophobicContact CG2-CB 3.69Å; L342-L346 VanDerWaalsContact O-CB 3.22Å; L342-L346 WeakPolarHBondContact O-CB 3.49Å; L342-L346 WeakPolarHBondContact O-CD1 3.37Å; L342-L346 WeakPolarHBondContact O-CG 3.46Å; L342-L346 PolarHBondContact O-N 3.25Å; L346-G348 VanDerWaalsContact C-N 3.28Å; L346-G348 PolarHBondContact O-N 2.94Å; L346-L385 HydrophobicContact CD2-CD1 3.76Å; L346-L385 HydrophobicContact CD2-CG 4.29Å; L346-L385 HydrophobicContact CG-CD1 3.93Å; L346-P391 HydrophobicContact CD2-CG 3.72Å; L346-L392 HydrophobicContact CB-CD1 4.21Å; L346-L392 HydrophobicContact CD1-CD1 4.3Å; L346-L392 HydrophobicContact CD2-CG 4.45Å
347G98.6Very high98.3Very high0 Ų013.4 Ų13.40%07%0.073CC..THydrogen-bonded Turntrans-75.9-8.4173.800000114.9R294 A343 T345R294-G347 VanDerWaalsContact CZ-O 3.28Å; R294-G347 PolarHBondContact NH1-O 2.67Å; R294-G347 PolarHBondContact NH2-O 3.38Å; A343-G347 PolarHBondContact O-N 2.94Å; T345-G347 PolarHBondContact O-N 3.25Å
348G98.6Very high98Very high7 Ų713.4 Ų13.47%0.0727%0.073CC..THydrogen-bonded Turntrans85.237.9172.300000115.7M67 Y68 A344 T345 L346 Q350M67-G348 WeakPolarHBondContact CE-O 3.38Å; Y68-G348 VanDerWaalsContact OH-CA 3.28Å; Y68-G348 WeakPolarHBondContact OH-CA 3.41Å; A344-G348 PolarHBondContact O-N 3.11Å; T345-G348 PolarHBondContact O-N 3.39Å; L346-G348 VanDerWaalsContact C-N 3.28Å; L346-G348 PolarHBondContact O-N 2.94Å; G348-Q350 PolarHBondContact O-NE2 3.18Å
349T98.7Very high97.7Very high0 Ų014.1 Ų14.10%07%0.074CC..  trans-60.7154.2173.6-169.30000114.5Y68 W73 T316 C318 A344 S351 L352Y68-T349 VanDerWaalsContact CE1-O 3.27Å; Y68-T349 WeakPolarHBondContact CE1-O 3.33Å; Y68-T349 PolarHBondContact OH-N 3.29Å; Y68-T349 PolarHBondContact OH-O 2.87Å; W73-T349 HydrophobicContact CB-CG2 4.37Å; W73-T349 HydrophobicContact CG-CG2 4.45Å; T316-T349 PolarHBondContact O-OG1 3.5Å; C318-T349 PolarHBondContact SG-OG1 3.07Å; C318-T349 VanDerWaalsContact SG-OG1 3.32Å; A344-T349 HydrophobicContact CB-CG2 4.26Å; A344-T349 WeakPolarHBondContact O-CB 3.27Å; A344-T349 WeakPolarHBondContact O-CG2 3.39Å; A344-T349 PolarHBondContact O-N 3.25Å; A344-T349 VanDerWaalsContact O-N 3.16Å; T349-S351 PolarHBondContact OG1-O 3.12Å; T349-L352 HydrophobicContact CG2-CB 4.3Å
350Q97.4Very high97.3Very high47 Ų4712.1 Ų12.122%0.227%0.065CC..SBendtrans-95.6-23176.9-75.86268.300112.8P63 T74 T316 G348P63-Q350 HydrophobicContact CG-CG 4.44Å; P63-Q350 VanDerWaalsContact CG-NE2 3.34Å; T74-Q350 PolarHBondContact N-O 2.73Å; T316-Q350 WeakPolarHBondContact O-CB 3.02Å; T316-Q350 PolarHBondContact O-N 3.43Å; G348-Q350 PolarHBondContact O-NE2 3.18Å
351S97.1Very high96.8Very high14 Ų1412.9 Ų12.910%0.0987%0.069CC..EExtended strand (participates in β ladder)trans-153.3152.7171.958.80000110.5T74 T316 H317 C318 T349T74-S351 WeakPolarHBondContact O-CA 3.48Å; T74-S351 WeakPolarHBondContact O-CB 3.37Å; T316-S351 PolarHBondContact O-N 3.28Å; H317-S351 CarbonylContact C-O 3.49Å; H317-S351 WeakPolarHBondContact CA-O 3.26Å; H317-S351 PolarHBondContact ND1-O 3.39Å; H317-S351 PolarHBondContact ND1-OG 2.81Å; C318-S351 PolarHBondContact N-O 2.92Å; T349-S351 PolarHBondContact OG1-O 3.12Å
352L97.8Very high96.3Very high0 Ų013.9 Ų13.90%08%0.079CC..EExtended strand (participates in β ladder)trans-137.5135.1-17317863.3000111.3T74 R76 C318 A341 A344 T345 T349 T354 Q376T74-L352 PolarHBondContact O-N 3.09Å; T74-L352 VanDerWaalsContact O-N 3.09Å; R76-L352 CarbonylContact C-O 3.37Å; R76-L352 PolarHBondContact N-O 3.26Å; R76-L352 VanDerWaalsContact N-O 3.08Å; C318-L352 HydrophobicContact CB-CD1 3.92Å; C318-L352 CarbonylContact O-C 3.44Å; C318-L352 WeakPolarHBondContact O-CA 3.37Å; C318-L352 WeakPolarHBondContact O-CD1 3.38Å; A341-L352 HydrophobicContact CB-CD2 3.96Å; A344-L352 HydrophobicContact CB-CD1 3.68Å; A344-L352 HydrophobicContact CB-CD2 4.31Å; T345-L352 HydrophobicContact CG2-CD2 4.13Å; T349-L352 HydrophobicContact CG2-CB 4.3Å; L352-T354 HydrophobicContact CD2-CG2 4.19Å; L352-T354 HydrophobicContact CG-CG2 4.3Å; L352-Q376 HydrophobicContact CD2-CG 4.01Å; L352-Q376 HydrophobicContact CG-CG 4.44Å; L352-Q376 PolarHBondContact O-NE2 3.42Å; L352-Q376 PolarHBondContact O-OE1 3.02Å
353H97.9Very high95.8Very high10 Ų1013.8 Ų13.85%0.0468%0.079CC..EExtended strand (participates in β ladder)trans-101.8128.7161.4177.7107.1000108.8Y78 H317 C318 Q319 T320 N355Y78-H353 WeakPolarHBondContact CB-CE1 3.48Å; Y78-H353 WeakPolarHBondContact CB-ND1 3.3Å; Y78-H353 PolarHBondContact N-CE1 2.94Å; Y78-H353 VanDerWaalsContact N-CE1 3.33Å; Y78-H353 PolarHBondContact N-ND1 3.25Å; H317-H353 PolarHBondContact CE1-N 2.74Å; C318-H353 PolarHBondContact O-N 3.28Å; Q319-H353 WeakPolarHBondContact CA-O 3.46Å; Q319-H353 HydrophobicContact CB-CB 3.99Å; Q319-H353 HydrophobicContact CG-CB 3.92Å; Q319-H353 PolarHBondContact NE2-CD2 3.05Å; T320-H353 PolarHBondContact N-O 3.36Å; H353-N355 PolarHBondContact CD2-N 2.74Å; H353-N355 PolarHBondContact CD2-OD1 3.35Å; H353-N355 PolarHBondContact NE2-OD1 3.08Å; H353-N355 VanDerWaalsContact NE2-OD1 3.09Å
354T98.5Very high95.5Very high0 Ų015.5 Ų15.50%09%0.09CC..  trans-107.8124.616836.30000108.9Q77 T320 T337 A341 L352 A372 T375 Q376Q77-T354 PolarHBondContact NE2-O 3.37Å; Q77-T354 PolarHBondContact OE1-OG1 3.41Å; T320-T354 HydrophobicContact CG2-CG2 4.09Å; T337-T354 HydrophobicContact CG2-CG2 3.83Å; A341-T354 HydrophobicContact CB-CG2 3.84Å; L352-T354 HydrophobicContact CD2-CG2 4.19Å; L352-T354 HydrophobicContact CG-CG2 4.3Å; T354-A372 WeakPolarHBondContact O-CB 3.5Å; T354-A372 PolarHBondContact OG1-O 3.47Å; T354-T375 HydrophobicContact CG2-CG2 4.41Å; T354-Q376 HydrophobicContact CG2-CG 3.59Å; T354-Q376 PolarHBondContact OG1-NE2 3.17Å
355N97.7Very high95.1Very high2 Ų216.8 Ų16.81%0.01110%0.098CC..  trans-68154.7178.8-61.6-19.1000110Q319 T320 S321 G322 L325 T337 H353Q319-N355 PolarHBondContact NE2-OD1 3.37Å; T320-N355 PolarHBondContact O-ND2 3.48Å; T320-N355 PolarHBondContact OG1-N 2.91Å; T320-N355 PolarHBondContact OG1-ND2 2.84Å; T320-N355 PolarHBondContact OG1-OD1 2.83Å; S321-N355 PolarHBondContact O-ND2 3.27Å; G322-N355 WeakPolarHBondContact CA-ND2 3.49Å; G322-N355 PolarHBondContact N-ND2 3.15Å; L325-N355 HydrophobicContact CD1-CB 3.54Å; T337-N355 WeakPolarHBondContact CG2-O 3.49Å; H353-N355 PolarHBondContact CD2-N 2.74Å; H353-N355 PolarHBondContact CD2-OD1 3.35Å; H353-N355 PolarHBondContact NE2-OD1 3.08Å; H353-N355 VanDerWaalsContact NE2-OD1 3.09Å
356A97Very high94.8Very high3 Ų320.7 Ų20.73%0.02512%0.119CC..  trans-80157.7173.800000110.7L325 D358 E359 P364 A372L325-A356 WeakPolarHBondContact CD1-O 3.41Å; A356-D358 WeakPolarHBondContact CB-OD1 3.13Å; A356-D358 PolarHBondContact O-N 3.46Å; A356-E359 WeakPolarHBondContact O-CB 3.42Å; A356-E359 PolarHBondContact O-N 2.95Å; A356-P364 HydrophobicContact CB-CB 3.71Å; A356-P364 HydrophobicContact CB-CG 3.73Å; A356-A372 HydrophobicContact CB-CB 4.47Å
357F96.8Very high94.6Very high9 Ų923.7 Ų23.74%0.03913%0.131CC..THydrogen-bonded Turntrans-70.5-16.4-174.874.8-95.9000112.9P330 Y331 N333 V334 F367 I371 T467P330-F357 HydrophobicContact CB-CD2 4.25Å; Y331-F357 HydrophobicContact CE1-CE2 4.31Å; Y331-F357 HydrophobicContact CE1-CZ 4.27Å; N333-F357 HydrophobicContact CB-CB 3.96Å; N333-F357 PolarHBondContact ND2-O 3Å; V334-F357 HydrophobicContact CG2-CB 3.77Å; V334-F357 HydrophobicContact CG2-CD1 4.4Å; V334-F357 HydrophobicContact CG2-CG 4.25Å; F357-F367 AromaticContact CE1-CD1 3.66Å; F357-F367 HydrophobicContact CE1-CD1 3.66Å; F357-F367 AromaticContact CE1-CE1 3.54Å; F357-F367 HydrophobicContact CE1-CE1 3.54Å; F357-F367 AromaticContact CZ-CD1 3.88Å; F357-F367 HydrophobicContact CZ-CD1 3.88Å; F357-F367 AromaticContact CZ-CE1 3.72Å; F357-F367 HydrophobicContact CZ-CE1 3.72Å; F357-I371 HydrophobicContact CD1-CD1 4.18Å; F357-I371 HydrophobicContact CE1-CD1 4.06Å; F357-T467 HydrophobicContact CE2-CG2 4.08Å
358D93.8Very high94.5Very high2 Ų223.7 Ų23.71%0.01113%0.131CC..THydrogen-bonded Turntrans-95.210.3179.851.6-6.4000113.4A356 A360 L361 G362 T365 S368A356-D358 WeakPolarHBondContact CB-OD1 3.13Å; A356-D358 PolarHBondContact O-N 3.46Å; D358-A360 VanDerWaalsContact C-N 3.29Å; D358-A360 PolarHBondContact O-N 2.73Å; D358-L361 WeakPolarHBondContact O-CB 3.4Å; D358-L361 PolarHBondContact O-N 2.87Å; D358-G362 PolarHBondContact O-N 3.34Å; D358-T365 PolarHBondContact OD2-N 2.83Å; D358-S368 VanDerWaalsContact CG-CB 3.42Å; D358-S368 WeakPolarHBondContact OD1-CB 3.39Å; D358-S368 PolarHBondContact OD1-OG 3.09Å; D358-S368 WeakPolarHBondContact OD2-CB 3.41Å; D358-S368 PolarHBondContact OD2-OG 2.99Å
359E91.8Very high94.3Very high62 Ų6223.8 Ų23.829%0.2913%0.131SC..THydrogen-bonded Turntrans-51.4-42.2-178.1-174.975.9-169.600113.9L325 A356 L361L325-E359 HydrophobicContact CB-CB 4.36Å; L325-E359 HydrophobicContact CD1-CB 3.53Å; L325-E359 HydrophobicContact CD1-CG 4.04Å; A356-E359 WeakPolarHBondContact O-CB 3.42Å; A356-E359 PolarHBondContact O-N 2.95Å; E359-L361 PolarHBondContact O-N 2.72Å
360A90Very high94.2Very high13 Ų1329 Ų2911%0.10715%0.151CC..THydrogen-bonded Turntrans-77.8-4.7-178.400000113.7E327 D358E327-A360 HydrophobicContact CB-CB 4.35Å; D358-A360 VanDerWaalsContact C-N 3.29Å; D358-A360 PolarHBondContact O-N 2.73Å
361L89.3Confident94.2Very high15 Ų1528.5 Ų28.58%0.07915%0.149CC..THydrogen-bonded Turntrans-107.8-37.2-179.9-68.3163.1000111.8E327 P330 D358 E359 T467 V469E327-L361 HydrophobicContact CG-CD2 3.56Å; E327-L361 HydrophobicContact CG-CG 4.34Å; P330-L361 HydrophobicContact CB-CD1 4.3Å; P330-L361 HydrophobicContact CG-CD1 4.32Å; D358-L361 WeakPolarHBondContact O-CB 3.4Å; D358-L361 PolarHBondContact O-N 2.87Å; E359-L361 PolarHBondContact O-N 2.72Å; L361-T467 HydrophobicContact CD1-CG2 3.76Å; L361-V469 HydrophobicContact CB-CG2 3.79Å
362G87.7Confident94.2Very high21 Ų2127.9 Ų27.922%0.21615%0.145CC..SBendtrans174.3-160.9179.100000112.7D358D358-G362 PolarHBondContact O-N 3.34Å
363L88.9Confident94.2Very high51 Ų5128.7 Ų28.727%0.26715%0.148SC..SBendtrans-75.2151.5178.6-63.6-170.7000111.9F81 T365 L470 I472F81-L363 HydrophobicContact CB-CD1 3.55Å; F81-L363 HydrophobicContact CG-CD1 4.46Å; L363-T365 PolarHBondContact O-N 3.36Å; L363-L470 HydrophobicContact CB-CD2 4.11Å; L363-I472 HydrophobicContact CD1-CD1 3.66Å
364P91.6Very high94.2Very high36 Ų3630.8 Ų30.823%0.23416%0.16CC..PPolyproline II helixtrans-58.9133.4-176.3-25.433.7000114.2A356 A369A356-P364 HydrophobicContact CB-CB 3.71Å; A356-P364 HydrophobicContact CB-CG 3.73Å; P364-A369 HydrophobicContact CB-CB 4.13Å
365T91.6Very high94.2Very high27 Ų2731.4 Ų31.417%0.16616%0.163CC..PPolyproline II helixtrans-74.6165.8164.364.30000111.9D358 L363 F367 S368 A369D358-T365 PolarHBondContact OD2-N 2.83Å; L363-T365 PolarHBondContact O-N 3.36Å; T365-F367 PolarHBondContact O-N 2.69Å; T365-F367 PolarHBondContact OG1-N 3.47Å; T365-S368 PolarHBondContact N-OG 3.5Å; T365-S368 PolarHBondContact O-N 3.07Å; T365-S368 PolarHBondContact O-OG 3.32Å; T365-S368 PolarHBondContact OG1-N 2.99Å; T365-S368 VanDerWaalsContact OG1-N 3.1Å; T365-S368 PolarHBondContact OG1-OG 3.25Å; T365-A369 WeakPolarHBondContact O-CB 3.35Å; T365-A369 PolarHBondContact O-N 3.2Å
366D91.1Very high94.2Very high86 Ų8631.3 Ų31.346%0.4616%0.163SC..Hα-helixtrans-57.9-31.4170.9-85.8-52.7000111.5R93 R370R93-D366 IonicContact CZ-OD1 2.72Å; R93-D366 IonicContact CZ-OD2 3.7Å; R93-D366 IonicContact NE-OD1 3.57Å; R93-D366 PolarHBondContact NE-OD1 2.89Å; R93-D366 IonicContact NE-OD2 3.55Å; R93-D366 IonicContact NH2-OD1 3.88Å; R93-D366 PolarHBondContact NH2-OD1 2.96Å; R93-D366 IonicContact NH2-OD2 3.78Å; R93-D366 PolarHBondContact NH2-OD2 3.46Å; D366-R370 WeakPolarHBondContact O-CB 3.42Å; D366-R370 PolarHBondContact O-N 3.33Å
367F94.9Very high94.2Very high92 Ų9233.4 Ų33.440%0.40417%0.173SC..Hα-helixtrans-70-51.6177.8172.7-105.9000112.2Y331 F357 T365 R370 I371Y331-F367 HydrophobicContact CE1-CE1 4.47Å; F357-F367 AromaticContact CE1-CD1 3.66Å; F357-F367 HydrophobicContact CE1-CD1 3.66Å; F357-F367 AromaticContact CE1-CE1 3.54Å; F357-F367 HydrophobicContact CE1-CE1 3.54Å; F357-F367 AromaticContact CZ-CD1 3.88Å; F357-F367 HydrophobicContact CZ-CD1 3.88Å; F357-F367 AromaticContact CZ-CE1 3.72Å; F357-F367 HydrophobicContact CZ-CE1 3.72Å; T365-F367 PolarHBondContact O-N 2.69Å; T365-F367 PolarHBondContact OG1-N 3.47Å; F367-R370 WeakPolarHBondContact O-CB 3.36Å; F367-R370 PolarHBondContact O-N 3.43Å; F367-I371 HydrophobicContact CD1-CD1 4.34Å; F367-I371 HydrophobicContact CE1-CD1 3.71Å; F367-I371 HydrophobicContact CE2-CD1 4.1Å; F367-I371 HydrophobicContact CZ-CD1 3.57Å; F367-I371 PolarHBondContact O-N 2.93Å
368S95.7Very high94.3Very high0 Ų036.9 Ų36.90%019%0.191CC..Hα-helixtrans-71.5-38.3-177.569.30000112.1D358 T365 R370 I371 A372D358-S368 VanDerWaalsContact CG-CB 3.42Å; D358-S368 WeakPolarHBondContact OD1-CB 3.39Å; D358-S368 PolarHBondContact OD1-OG 3.09Å; D358-S368 WeakPolarHBondContact OD2-CB 3.41Å; D358-S368 PolarHBondContact OD2-OG 2.99Å; T365-S368 PolarHBondContact N-OG 3.5Å; T365-S368 PolarHBondContact O-N 3.07Å; T365-S368 PolarHBondContact O-OG 3.32Å; T365-S368 PolarHBondContact OG1-N 2.99Å; T365-S368 VanDerWaalsContact OG1-N 3.1Å; T365-S368 PolarHBondContact OG1-OG 3.25Å; S368-R370 VanDerWaalsContact C-N 3.28Å; S368-R370 PolarHBondContact O-N 3.28Å; S368-I371 PolarHBondContact O-N 3.31Å; S368-I371 VanDerWaalsContact O-N 3.12Å; S368-A372 PolarHBondContact O-N 3.32Å
369A94.8Very high94.5Very high9 Ų937.1 Ų37.17%0.07419%0.192CC..Hα-helixtrans-61.5-35173.700000112.5F90 P364 T365 R373F90-A369 HydrophobicContact CZ-CB 3.95Å; P364-A369 HydrophobicContact CB-CB 4.13Å; T365-A369 WeakPolarHBondContact O-CB 3.35Å; T365-A369 PolarHBondContact O-N 3.2Å; A369-R373 WeakPolarHBondContact O-CB 3.29Å; A369-R373 PolarHBondContact O-N 2.82Å
370R95.9Very high94.8Very high111 Ų11135.1 Ų35.142%0.41918%0.183SC..Hα-helixtrans-64.9-44.4173.3179.7-177.567.994.33.6111.5D366 F367 S368 R373 N374D366-R370 WeakPolarHBondContact O-CB 3.42Å; D366-R370 PolarHBondContact O-N 3.33Å; F367-R370 WeakPolarHBondContact O-CB 3.36Å; F367-R370 PolarHBondContact O-N 3.43Å; S368-R370 VanDerWaalsContact C-N 3.28Å; S368-R370 PolarHBondContact O-N 3.28Å; R370-R373 PolarHBondContact O-N 2.82Å; R370-N374 VanDerWaalsContact O-CB 3.31Å; R370-N374 WeakPolarHBondContact O-CB 3.27Å; R370-N374 VanDerWaalsContact O-CG 3.31Å; R370-N374 PolarHBondContact O-N 3.12Å
371I97.9Very high95.2Very high35 Ų3540.9 Ų40.918%0.17921%0.208CC..Hα-helixtrans-61.4-49.7176.9-67.7173.3000109.7V334 F357 F367 S368 R373 N374 T375V334-I371 HydrophobicContact CG1-CG2 3.99Å; V334-I371 HydrophobicContact CG2-CG2 4.04Å; F357-I371 HydrophobicContact CD1-CD1 4.18Å; F357-I371 HydrophobicContact CE1-CD1 4.06Å; F367-I371 HydrophobicContact CD1-CD1 4.34Å; F367-I371 HydrophobicContact CE1-CD1 3.71Å; F367-I371 HydrophobicContact CE2-CD1 4.1Å; F367-I371 HydrophobicContact CZ-CD1 3.57Å; F367-I371 PolarHBondContact O-N 2.93Å; S368-I371 PolarHBondContact O-N 3.31Å; S368-I371 VanDerWaalsContact O-N 3.12Å; I371-R373 VanDerWaalsContact C-N 3.34Å; I371-R373 PolarHBondContact O-N 3.26Å; I371-N374 PolarHBondContact O-N 3Å; I371-N374 VanDerWaalsContact O-N 3.08Å; I371-T375 PolarHBondContact O-N 3.37Å; I371-T375 PolarHBondContact O-OG1 3.03Å
372A97.7Very high95.6Very high2 Ų247 Ų472%0.01724%0.236CC..Hα-helixtrans-54.5-47.3178.400000112.5T354 A356 S368 T375T354-A372 WeakPolarHBondContact O-CB 3.5Å; T354-A372 PolarHBondContact OG1-O 3.47Å; A356-A372 HydrophobicContact CB-CB 4.47Å; S368-A372 PolarHBondContact O-N 3.32Å; A372-T375 WeakPolarHBondContact O-CB 3.27Å; A372-T375 PolarHBondContact O-N 3.32Å
373R97.3Very high96.1Very high17 Ų1748.6 Ų48.66%0.06424%0.244CC..Hα-helixtrans-63.3-44.9175.5-179.5176.761.1-102.9-2.9111.9I75 N94 A97 A369 R370 I371 T375 Q376 I377I75-R373 HydrophobicContact CG2-CG 4.29Å; N94-R373 PolarHBondContact OD1-NH1 3.03Å; A97-R373 VanDerWaalsContact CB-NH2 3.3Å; A97-R373 PolarHBondContact O-NE 3.48Å; A369-R373 WeakPolarHBondContact O-CB 3.29Å; A369-R373 PolarHBondContact O-N 2.82Å; R370-R373 PolarHBondContact O-N 2.82Å; I371-R373 VanDerWaalsContact C-N 3.34Å; I371-R373 PolarHBondContact O-N 3.26Å; R373-T375 VanDerWaalsContact C-N 3.28Å; R373-T375 PolarHBondContact O-N 3.01Å; R373-Q376 PolarHBondContact O-N 2.74Å; R373-Q376 VanDerWaalsContact O-N 3.14Å; R373-I377 HydrophobicContact CG-CD1 3.98Å; R373-I377 PolarHBondContact O-N 2.6Å
374N98.1Very high96.5Very high54 Ų5451.2 Ų51.229%0.28925%0.254SS..Hα-helixtrans-65.9-29-178.5-795.7000112.7R370 I371 Q376 I377 I378R370-N374 VanDerWaalsContact O-CB 3.31Å; R370-N374 WeakPolarHBondContact O-CB 3.27Å; R370-N374 VanDerWaalsContact O-CG 3.31Å; R370-N374 PolarHBondContact O-N 3.12Å; I371-N374 PolarHBondContact O-N 3Å; I371-N374 VanDerWaalsContact O-N 3.08Å; N374-Q376 VanDerWaalsContact C-N 3.25Å; N374-Q376 PolarHBondContact O-N 3.03Å; N374-I377 PolarHBondContact O-N 3.13Å; N374-I378 WeakPolarHBondContact O-CB 3.35Å; N374-I378 VanDerWaalsContact O-CG1 3.3Å; N374-I378 WeakPolarHBondContact O-CG1 3.46Å; N374-I378 PolarHBondContact O-N 3.47Å
375T98.7Very high96.8Very high12 Ų1250.5 Ų50.57%0.07425%0.249CC..Hα-helixtrans-52.3-46.8170.4-60.60000110.8T338 A341 T354 I371 A372 R373 I379T338-T375 HydrophobicContact CG2-CG2 4.4Å; A341-T375 HydrophobicContact CB-CG2 4.17Å; T354-T375 HydrophobicContact CG2-CG2 4.41Å; I371-T375 PolarHBondContact O-N 3.37Å; I371-T375 PolarHBondContact O-OG1 3.03Å; A372-T375 WeakPolarHBondContact O-CB 3.27Å; A372-T375 PolarHBondContact O-N 3.32Å; R373-T375 VanDerWaalsContact C-N 3.28Å; R373-T375 PolarHBondContact O-N 3.01Å; T375-I379 HydrophobicContact CG2-CD1 4.23Å; T375-I379 WeakPolarHBondContact O-CD1 3.49Å; T375-I379 VanDerWaalsContact O-CG1 3.24Å; T375-I379 WeakPolarHBondContact O-CG1 3.39Å; T375-I379 PolarHBondContact O-N 2.91Å
376Q98.4Very high97.1Very high0 Ų050.1 Ų50.10%025%0.247CC..Hα-helixtrans-70.2-40.7178-59.9-169.74700112.7W73 I75 L352 T354 R373 N374 I379 Q380W73-Q376 HydrophobicContact CZ2-CB 4.27Å; I75-Q376 HydrophobicContact CD1-CB 4.02Å; I75-Q376 HydrophobicContact CG1-CB 4.02Å; L352-Q376 HydrophobicContact CD2-CG 4.01Å; L352-Q376 HydrophobicContact CG-CG 4.44Å; L352-Q376 PolarHBondContact O-NE2 3.42Å; L352-Q376 PolarHBondContact O-OE1 3.02Å; T354-Q376 HydrophobicContact CG2-CG 3.59Å; T354-Q376 PolarHBondContact OG1-NE2 3.17Å; R373-Q376 PolarHBondContact O-N 2.74Å; R373-Q376 VanDerWaalsContact O-N 3.14Å; N374-Q376 VanDerWaalsContact C-N 3.25Å; N374-Q376 PolarHBondContact O-N 3.03Å; Q376-I379 PolarHBondContact O-N 2.75Å; Q376-Q380 WeakPolarHBondContact O-CG 3.4Å; Q376-Q380 PolarHBondContact O-N 3Å
377I97.3Very high97.4Very high48 Ų4854.3 Ų54.325%0.24626%0.256CS..Hα-helixtrans-61.3-46.1179.4-64.3173.2000110.4I75 R373 N374 I379 Q380 E381I75-I377 HydrophobicContact CD1-CG1 3.64Å; R373-I377 HydrophobicContact CG-CD1 3.98Å; R373-I377 PolarHBondContact O-N 2.6Å; N374-I377 PolarHBondContact O-N 3.13Å; I377-I379 VanDerWaalsContact C-N 3.34Å; I377-I379 PolarHBondContact O-N 2.79Å; I377-Q380 PolarHBondContact O-N 3.41Å; I377-Q380 VanDerWaalsContact O-N 3.1Å; I377-E381 HydrophobicContact CG2-CG 4.01Å; I377-E381 WeakPolarHBondContact O-CB 3.39Å; I377-E381 WeakPolarHBondContact O-CG 3.48Å; I377-E381 PolarHBondContact O-N 2.79Å
378I98.5Very high97.5Very high82 Ų8254 Ų5442%0.42126%0.262SS..Hα-helixtrans-61.2-43177.7-69.2167.7000110.5N374 Q380 E381 E382 S383N374-I378 WeakPolarHBondContact O-CB 3.35Å; N374-I378 VanDerWaalsContact O-CG1 3.3Å; N374-I378 WeakPolarHBondContact O-CG1 3.46Å; N374-I378 PolarHBondContact O-N 3.47Å; I378-Q380 VanDerWaalsContact C-N 3.33Å; I378-Q380 PolarHBondContact O-N 3.3Å; I378-E381 PolarHBondContact O-N 2.97Å; I378-E382 HydrophobicContact CG2-CB 4.28Å; I378-E382 WeakPolarHBondContact O-CA 3.38Å; I378-E382 WeakPolarHBondContact O-CB 3.36Å; I378-E382 PolarHBondContact O-N 3.03Å; I378-S383 PolarHBondContact O-N 2.93Å
379I98.4Very high97.6Very high7 Ų755.2 Ų55.24%0.03627%0.269CS..Hα-helixtrans-62.5-41175.1-60.9165.4000110.5W73 A341 L342 T375 Q376 I377 S383 L385W73-I379 HydrophobicContact CH2-CB 4.03Å; W73-I379 HydrophobicContact CH2-CG2 3.65Å; W73-I379 HydrophobicContact CZ2-CB 4.42Å; W73-I379 HydrophobicContact CZ2-CG2 4.38Å; A341-I379 HydrophobicContact CB-CD1 3.59Å; L342-I379 HydrophobicContact CD2-CD1 4.19Å; L342-I379 HydrophobicContact CD2-CG1 4.2Å; L342-I379 HydrophobicContact CD2-CG2 4.18Å; L342-I379 HydrophobicContact CG-CD1 4.31Å; T375-I379 HydrophobicContact CG2-CD1 4.23Å; T375-I379 WeakPolarHBondContact O-CD1 3.49Å; T375-I379 VanDerWaalsContact O-CG1 3.24Å; T375-I379 WeakPolarHBondContact O-CG1 3.39Å; T375-I379 PolarHBondContact O-N 2.91Å; Q376-I379 PolarHBondContact O-N 2.75Å; I377-I379 VanDerWaalsContact C-N 3.34Å; I377-I379 PolarHBondContact O-N 2.79Å; I379-S383 WeakPolarHBondContact O-CB 3.48Å; I379-S383 PolarHBondContact O-OG 3.44Å; I379-L385 HydrophobicContact CG2-CD1 4.15Å
380Q97.8Very high97.8Very high20 Ų2055.4 Ų55.49%0.09327%0.269CS..Hα-helixtrans-66-45.9178.8-72.5-172.10.100113.3P72 W73 Q376 I377 I378P72-Q380 HydrophobicContact CB-CG 4.07Å; W73-Q380 HydrophobicContact CD2-CG 4.48Å; W73-Q380 HydrophobicContact CE3-CG 4.36Å; W73-Q380 HydrophobicContact CH2-CB 4.33Å; W73-Q380 HydrophobicContact CH2-CG 3.26Å; W73-Q380 HydrophobicContact CZ2-CG 3.43Å; W73-Q380 VanDerWaalsContact CZ2-CG 3.43Å; W73-Q380 HydrophobicContact CZ3-CG 3.78Å; W73-Q380 PolarHBondContact O-NE2 3.5Å; Q376-Q380 WeakPolarHBondContact O-CG 3.4Å; Q376-Q380 PolarHBondContact O-N 3Å; I377-Q380 PolarHBondContact O-N 3.41Å; I377-Q380 VanDerWaalsContact O-N 3.1Å; I378-Q380 VanDerWaalsContact C-N 3.33Å; I378-Q380 PolarHBondContact O-N 3.3Å
381E97.6Very high97.9Very high134 Ų13453.2 Ų53.263%0.62627%0.269SS*.Hα-helixtrans-98.7-28.7-164.4-58.6-72.5179.700113.4I377 I378I377-E381 HydrophobicContact CG2-CG 4.01Å; I377-E381 WeakPolarHBondContact O-CB 3.39Å; I377-E381 WeakPolarHBondContact O-CG 3.48Å; I377-E381 PolarHBondContact O-N 2.79Å; I378-E381 PolarHBondContact O-N 2.97Å
382E98.5Very high97.9Very high143 Ų14353.4 Ų53.467%0.66827%0.27SS*.THydrogen-bonded Turntrans-115.9-25.1-170.5-58.4-178.5-155.500114I378 E384I378-E382 HydrophobicContact CG2-CB 4.28Å; I378-E382 WeakPolarHBondContact O-CA 3.38Å; I378-E382 WeakPolarHBondContact O-CB 3.36Å; I378-E382 PolarHBondContact O-N 3.03Å; E382-E384 PolarHBondContact O-N 2.71Å
383S97.9Very high97.9Very high55 Ų5554.7 Ų54.739%0.38528%0.281SS..SBendtrans-81.5-8.4-172.881.80000115.5I378 I379 L385I378-S383 PolarHBondContact O-N 2.93Å; I379-S383 WeakPolarHBondContact O-CB 3.48Å; I379-S383 PolarHBondContact O-OG 3.44Å; S383-L385 PolarHBondContact O-N 2.93Å; S383-L385 WeakPolarHBondContact OG-CB 3.46Å; S383-L385 PolarHBondContact OG-N 2.85Å
384E97.1Very high97.9Very high105 Ų10556 Ų5649%0.49130%0.3SS..  trans58.16.9-171.6-60.2-64.4151.900115.2E382 C386 R387E382-E384 PolarHBondContact O-N 2.71Å; E384-C386 PolarHBondContact O-N 2.68Å; E384-R387 HydrophobicContact CB-CG 4.24Å; E384-R387 WeakPolarHBondContact O-CB 3.36Å; E384-R387 VanDerWaalsContact O-CG 3.28Å; E384-R387 WeakPolarHBondContact O-CG 3.25Å; E384-R387 PolarHBondContact O-N 3.24Å; E384-R387 VanDerWaalsContact O-N 3.11Å; E384-R387 IonicContact OE1-NH2 3.56Å; E384-R387 WeakPolarHBondContact OE2-CD 3.24Å; E384-R387 WeakPolarHBondContact OE2-CG 3.47Å; E384-R387 IonicContact OE2-CZ 3.38Å; E384-R387 IonicContact OE2-NE 3.11Å; E384-R387 PolarHBondContact OE2-NE 3.39Å; E384-R387 IonicContact OE2-NH2 3.8Å
385L97.1Very high97.9Very high22 Ų2255.6 Ų55.612%0.11530%0.301CS..G310 helixtrans-57.8-35.7-179.5-176.8151.6000112.5Y68 W73 L342 L346 I379 S383 R387Y68-L385 HydrophobicContact CD2-CD2 3.94Å; Y68-L385 HydrophobicContact CE2-CD2 4.15Å; W73-L385 HydrophobicContact CZ3-CD2 4.41Å; L342-L385 HydrophobicContact CD2-CD1 4.2Å; L346-L385 HydrophobicContact CD2-CD1 3.76Å; L346-L385 HydrophobicContact CD2-CG 4.29Å; L346-L385 HydrophobicContact CG-CD1 3.93Å; I379-L385 HydrophobicContact CG2-CD1 4.15Å; S383-L385 PolarHBondContact O-N 2.93Å; S383-L385 WeakPolarHBondContact OG-CB 3.46Å; S383-L385 PolarHBondContact OG-N 2.85Å; L385-R387 PolarHBondContact O-N 2.74Å; L385-R387 VanDerWaalsContact O-N 3.13Å
386C98.1Very high97.8Very high18 Ų1859.9 Ų59.912%0.12232%0.317CS..G310 helixtrans-71-2.6-178.5-62.80000114.3Y68 T69 E384Y68-C386 CarbonylContact C-O 3.45Å; T69-C386 VanDerWaalsContact CA-O 3.23Å; T69-C386 WeakPolarHBondContact CA-O 3.06Å; T69-C386 WeakPolarHBondContact CG2-O 3.35Å; T69-C386 PolarHBondContact N-O 3.49Å; E384-C386 PolarHBondContact O-N 2.68Å
387R97.7Very high97.8Very high174 Ų17462.1 Ų62.166%0.65733%0.326SS*.G310 helixtrans-82.1-18.6-175.8-59.7-59.2-175.1-162.9-6.8114.8T69 E384 L385T69-R387 WeakPolarHBondContact CG2-O 3.2Å; E384-R387 HydrophobicContact CB-CG 4.24Å; E384-R387 WeakPolarHBondContact O-CB 3.36Å; E384-R387 VanDerWaalsContact O-CG 3.28Å; E384-R387 WeakPolarHBondContact O-CG 3.25Å; E384-R387 PolarHBondContact O-N 3.24Å; E384-R387 VanDerWaalsContact O-N 3.11Å; E384-R387 IonicContact OE1-NH2 3.56Å; E384-R387 WeakPolarHBondContact OE2-CD 3.24Å; E384-R387 WeakPolarHBondContact OE2-CG 3.47Å; E384-R387 IonicContact OE2-CZ 3.38Å; E384-R387 IonicContact OE2-NE 3.11Å; E384-R387 PolarHBondContact OE2-NE 3.39Å; E384-R387 IonicContact OE2-NH2 3.8Å; L385-R387 PolarHBondContact O-N 2.74Å; L385-R387 VanDerWaalsContact O-N 3.13Å
388T97.7Very high97.9Very high86 Ų8659.9 Ų59.953%0.52831%0.314SS..SBendtrans-134.3137.8-176.3-59.60000111.1P391T388-P391 HydrophobicContact CG2-CB 4.38Å
389V98.2Very high97.9Very high25 Ų2556.4 Ų56.415%0.15230%0.296CS..SBendtrans-77.7127.7176.5-177.10000110.5P54 R61 T66 M67 T69P54-V389 HydrophobicContact CB-CG1 3.59Å; P54-V389 HydrophobicContact CG-CG1 3.67Å; R61-V389 PolarHBondContact NH2-O 3.21Å; T66-V389 VanDerWaalsContact O-CG2 3.29Å; T66-V389 WeakPolarHBondContact O-CG2 3.44Å; M67-V389 HydrophobicContact CB-CG1 3.95Å; M67-V389 HydrophobicContact CB-CG2 4.21Å; M67-V389 HydrophobicContact CG-CG1 3.63Å; T69-V389 HydrophobicContact CG2-CG2 3.81Å
390D98.1Very high97.9Very high13 Ų1356.5 Ų56.57%0.0730%0.297CS..SBendtrans4564.7177.6-17434.5000111.6R61 R291 L392 A393R61-D390 WeakPolarHBondContact CA-OD2 3.41Å; R61-D390 HydrophobicContact CB-CB 3.98Å; R61-D390 WeakPolarHBondContact CB-OD2 3.44Å; R61-D390 WeakPolarHBondContact CG-OD2 3.29Å; R61-D390 IonicContact CZ-OD2 3.77Å; R61-D390 IonicContact NE-OD2 3.52Å; R61-D390 PolarHBondContact NE-OD2 3.16Å; R61-D390 PolarHBondContact NH2-O 3.03Å; R291-D390 IonicContact NE-OD1 3.03Å; R291-D390 IonicContact NE-OD2 2.93Å; R291-D390 IonicContact NH2-OD2 3.1Å; R291-D390 PolarHBondContact NH2-OD2 3.09Å; D390-L392 PolarHBondContact O-N 3.05Å; D390-L392 VanDerWaalsContact O-N 3.07Å; D390-A393 VanDerWaalsContact O-CB 3.29Å; D390-A393 WeakPolarHBondContact O-CB 3.42Å; D390-A393 PolarHBondContact O-N 2.72Å; D390-A393 WeakPolarHBondContact OD2-CB 3.37Å
391P97.7Very high97.9Very high65 Ų6555.5 Ų55.542%0.42229%0.293SS..THydrogen-bonded Turntrans-65.1-13.3-16926.9-36000114L346 T388L346-P391 HydrophobicContact CD2-CG 3.72Å; T388-P391 HydrophobicContact CG2-CB 4.38Å
392L97.6Very high98Very high39 Ų3949.1 Ų49.120%0.20426%0.263CS..THydrogen-bonded Turntrans-91.7-2.5176.9-62.5-177.3000113.8V287 L346 D390 S395 I398V287-L392 HydrophobicContact CB-CD1 4.44Å; V287-L392 HydrophobicContact CG1-CD1 3.8Å; V287-L392 HydrophobicContact CG2-CD1 4.25Å; L346-L392 HydrophobicContact CB-CD1 4.21Å; L346-L392 HydrophobicContact CD1-CD1 4.3Å; L346-L392 HydrophobicContact CD2-CG 4.45Å; D390-L392 PolarHBondContact O-N 3.05Å; D390-L392 VanDerWaalsContact O-N 3.07Å; L392-S395 WeakPolarHBondContact O-CB 3.1Å; L392-S395 PolarHBondContact O-N 2.84Å; L392-S395 VanDerWaalsContact O-N 3.14Å; L392-I398 HydrophobicContact CB-CG1 4.26Å; L392-I398 HydrophobicContact CB-CG2 4.39Å; L392-I398 HydrophobicContact CD1-CD1 4.44Å; L392-I398 HydrophobicContact CD1-CG1 4.33Å
393A97.6Very high98Very high30 Ų3042.4 Ų42.425%0.24823%0.231CC..THydrogen-bonded Turntrans-58.7139.4178.800000112.3D390 S395 E399D390-A393 VanDerWaalsContact O-CB 3.29Å; D390-A393 WeakPolarHBondContact O-CB 3.42Å; D390-A393 PolarHBondContact O-N 2.72Å; D390-A393 WeakPolarHBondContact OD2-CB 3.37Å; A393-S395 PolarHBondContact O-N 3.37Å; A393-E399 WeakPolarHBondContact CA-OE1 3.46Å
394G97.1Very high98Very high44 Ų4442.2 Ų42.245%0.45423%0.225SC..THydrogen-bonded Turntrans79.3-4.8-176.400000114.4Y396 E399G394-Y396 PolarHBondContact O-N 2.93Å; G394-E399 PolarHBondContact N-OE1 2.92Å
395S98.2Very high98.1Very high46 Ų4637.2 Ų37.232%0.32220%0.201SC..  trans-61.7120.4168.1171.60000109.9L392 A393 Y397 I398 E399L392-S395 WeakPolarHBondContact O-CB 3.1Å; L392-S395 PolarHBondContact O-N 2.84Å; L392-S395 VanDerWaalsContact O-N 3.14Å; A393-S395 PolarHBondContact O-N 3.37Å; S395-Y397 PolarHBondContact O-N 3.22Å; S395-Y397 VanDerWaalsContact O-N 3.09Å; S395-I398 PolarHBondContact O-N 3.3Å; S395-I398 VanDerWaalsContact O-N 3.08Å; S395-E399 WeakPolarHBondContact O-CG 3.42Å; S395-E399 PolarHBondContact O-N 3.26Å
396Y98Very high98.2Very high102 Ų10236.2 Ų36.240%0.420%0.196SC..Hα-helixtrans-51.2-38.4179.9-48.8-39.5000112.2Y39 T40 E41 L44 G394 S400Y39-Y396 WeakPolarHBondContact O-CD2 3.38Å; T40-Y396 VanDerWaalsContact C-CG 3.45Å; T40-Y396 WeakPolarHBondContact O-CB 3.46Å; E41-Y396 HydrophobicContact CB-CE1 4.16Å; L44-Y396 HydrophobicContact CD1-CD1 3.66Å; L44-Y396 HydrophobicContact CD1-CE1 3.89Å; L44-Y396 HydrophobicContact CD2-CD1 4.32Å; L44-Y396 HydrophobicContact CG-CD1 3.83Å; L44-Y396 HydrophobicContact CG-CE1 4.49Å; G394-Y396 PolarHBondContact O-N 2.93Å; Y396-S400 VanDerWaalsContact O-CB 3.27Å; Y396-S400 WeakPolarHBondContact O-CB 3.33Å; Y396-S400 PolarHBondContact O-N 3.41Å; Y396-S400 PolarHBondContact O-OG 3.31Å
397Y98.4Very high98.2Very high46 Ų4640.1 Ų40.118%0.1821%0.211CC..Hα-helixtrans-71.8-50.1178.2175.4-142.4000112.4I35 Y39 F284 S395 S400 L401I35-Y397 HydrophobicContact CD1-CE2 3.91Å; I35-Y397 HydrophobicContact CG2-CE2 3.81Å; Y39-Y397 AromaticContact CD2-CD2 3.72Å; Y39-Y397 HydrophobicContact CD2-CD2 3.72Å; Y39-Y397 HydrophobicContact CD2-CG 4.05Å; Y39-Y397 HydrophobicContact CE1-CD2 4.32Å; Y39-Y397 AromaticContact CE2-CD2 3.34Å; Y39-Y397 HydrophobicContact CE2-CD2 3.34Å; Y39-Y397 AromaticContact CE2-CE2 3.91Å; Y39-Y397 HydrophobicContact CE2-CE2 3.91Å; Y39-Y397 HydrophobicContact CE2-CG 4.11Å; Y39-Y397 HydrophobicContact CG-CD2 4.36Å; Y39-Y397 AromaticContact CZ-CD2 3.69Å; F284-Y397 HydrophobicContact CB-CE1 3.64Å; F284-Y397 AromaticContact CD2-CE1 3.74Å; F284-Y397 HydrophobicContact CD2-CE1 3.74Å; F284-Y397 HydrophobicContact CG-CD1 4.41Å; F284-Y397 AromaticContact CG-CE1 3.73Å; F284-Y397 HydrophobicContact CG-CE1 3.73Å; S395-Y397 PolarHBondContact O-N 3.22Å; S395-Y397 VanDerWaalsContact O-N 3.09Å; Y397-S400 PolarHBondContact O-N 3.35Å; Y397-L401 HydrophobicContact CD2-CB 4.42Å; Y397-L401 HydrophobicContact CE2-CB 4.19Å; Y397-L401 HydrophobicContact CE2-CD2 3.91Å; Y397-L401 HydrophobicContact CE2-CG 4.48Å; Y397-L401 VanDerWaalsContact O-CB 3.25Å; Y397-L401 WeakPolarHBondContact O-CB 3.47Å; Y397-L401 PolarHBondContact O-N 3.47Å
398I98.6Very high98.2Very high1 Ų134.4 Ų34.41%0.00519%0.192CC..Hα-helixtrans-69.3-39.5-173-58.9-61.9000111.8F284 V287 L392 S395 L401 T402F284-I398 HydrophobicContact CB-CD1 3.84Å; F284-I398 HydrophobicContact CD1-CD1 3.52Å; F284-I398 HydrophobicContact CE1-CD1 4.41Å; F284-I398 HydrophobicContact CG-CD1 4.01Å; V287-I398 HydrophobicContact CG1-CG2 4.37Å; L392-I398 HydrophobicContact CB-CG1 4.26Å; L392-I398 HydrophobicContact CB-CG2 4.39Å; L392-I398 HydrophobicContact CD1-CD1 4.44Å; L392-I398 HydrophobicContact CD1-CG1 4.33Å; S395-I398 PolarHBondContact O-N 3.3Å; S395-I398 VanDerWaalsContact O-N 3.08Å; I398-L401 PolarHBondContact O-N 3.38Å; I398-T402 VanDerWaalsContact O-CB 3.31Å; I398-T402 WeakPolarHBondContact O-CB 3.45Å; I398-T402 PolarHBondContact O-N 3.42Å; I398-T402 PolarHBondContact O-OG1 3.07Å
399E98.7Very high98.3Very high10 Ų1030.3 Ų30.35%0.04717%0.167CC..Hα-helixtrans-65.2-46.8176.1-58.2-60.9177.200111L44 L47 T50 R291 A393 G394 S395 L401 T402 D403L44-E399 HydrophobicContact CD2-CB 3.61Å; L44-E399 HydrophobicContact CD2-CG 3.9Å; L47-E399 HydrophobicContact CD1-CB 3.86Å; T50-E399 HydrophobicContact CG2-CB 4.09Å; T50-E399 HydrophobicContact CG2-CG 4.25Å; R291-E399 IonicContact CZ-OE1 2.76Å; R291-E399 IonicContact CZ-OE2 2.91Å; R291-E399 VanDerWaalsContact CZ-OE2 3.29Å; R291-E399 IonicContact NH1-OE1 2.67Å; R291-E399 IonicContact NH1-OE2 2.99Å; R291-E399 PolarHBondContact NH1-OE2 2.86Å; R291-E399 IonicContact NH2-OE1 3.35Å; R291-E399 PolarHBondContact NH2-OE1 3.28Å; R291-E399 IonicContact NH2-OE2 3.38Å; R291-E399 PolarHBondContact NH2-OE2 3.11Å; A393-E399 WeakPolarHBondContact CA-OE1 3.46Å; G394-E399 PolarHBondContact N-OE1 2.92Å; S395-E399 WeakPolarHBondContact O-CG 3.42Å; S395-E399 PolarHBondContact O-N 3.26Å; E399-L401 VanDerWaalsContact C-N 3.31Å; E399-L401 PolarHBondContact O-N 3.34Å; E399-T402 PolarHBondContact O-N 3.29Å; E399-D403 WeakPolarHBondContact O-CB 3.2Å; E399-D403 PolarHBondContact O-N 3.41Å
400S98.6Very high98.3Very high8 Ų832.4 Ų32.46%0.05617%0.172CC..Hα-helixtrans-61.1-38.3176.2-59.70000112.8D43 Y396 Y397 Q404D43-S400 PolarHBondContact O-OG 3Å; Y396-S400 VanDerWaalsContact O-CB 3.27Å; Y396-S400 WeakPolarHBondContact O-CB 3.33Å; Y396-S400 PolarHBondContact O-N 3.41Å; Y396-S400 PolarHBondContact O-OG 3.31Å; Y397-S400 PolarHBondContact O-N 3.35Å; S400-Q404 VanDerWaalsContact O-CG 3.31Å; S400-Q404 WeakPolarHBondContact O-CG 3.31Å; S400-Q404 PolarHBondContact O-N 3.46Å; S400-Q404 VanDerWaalsContact O-N 3.12Å; S400-Q404 PolarHBondContact O-NE2 3.16Å; S400-Q404 VanDerWaalsContact O-NE2 3.15Å
401L98.6Very high98.3Very high0 Ų034 Ų340%019%0.186CC..Hα-helixtrans-70.6-42.8178.4-174.258.4000111.1I33 I35 F284 M285 A288 Y397 I398 E399 D403 Q404 I405I33-L401 HydrophobicContact CD1-CD1 4.02Å; I33-L401 HydrophobicContact CG2-CD1 3.91Å; I35-L401 HydrophobicContact CD1-CD1 3.72Å; F284-L401 HydrophobicContact CB-CD2 4.34Å; M285-L401 HydrophobicContact CE-CD1 3.84Å; M285-L401 HydrophobicContact SD-CD1 3.92Å; M285-L401 HydrophobicContact SD-CD2 4.39Å; M285-L401 HydrophobicContact SD-CG 4.34Å; A288-L401 HydrophobicContact CB-CB 4.02Å; A288-L401 HydrophobicContact CB-CD2 3.81Å; A288-L401 HydrophobicContact CB-CG 3.6Å; Y397-L401 HydrophobicContact CD2-CB 4.42Å; Y397-L401 HydrophobicContact CE2-CB 4.19Å; Y397-L401 HydrophobicContact CE2-CD2 3.91Å; Y397-L401 HydrophobicContact CE2-CG 4.48Å; Y397-L401 VanDerWaalsContact O-CB 3.25Å; Y397-L401 WeakPolarHBondContact O-CB 3.47Å; Y397-L401 PolarHBondContact O-N 3.47Å; I398-L401 PolarHBondContact O-N 3.38Å; E399-L401 VanDerWaalsContact C-N 3.31Å; E399-L401 PolarHBondContact O-N 3.34Å; L401-D403 VanDerWaalsContact C-N 3.34Å; L401-D403 PolarHBondContact O-N 3.2Å; L401-Q404 PolarHBondContact O-N 2.89Å; L401-I405 HydrophobicContact CG-CD1 4.49Å; L401-I405 WeakPolarHBondContact O-CG1 3.41Å; L401-I405 PolarHBondContact O-N 2.89Å
402T98.8Very high98.3Very high0 Ų031.7 Ų31.70%017%0.171CC..Hα-helixtrans-59.5-46.4176.5-56.60000110.6V49 R291 A292 I398 E399 Q404 I405 V406V49-T402 HydrophobicContact CB-CG2 4.3Å; V49-T402 HydrophobicContact CG1-CG2 4.13Å; V49-T402 HydrophobicContact CG2-CG2 4.27Å; R291-T402 HydrophobicContact CB-CG2 3.62Å; R291-T402 PolarHBondContact NH1-OG1 2.98Å; A292-T402 HydrophobicContact CB-CG2 4.05Å; I398-T402 VanDerWaalsContact O-CB 3.31Å; I398-T402 WeakPolarHBondContact O-CB 3.45Å; I398-T402 PolarHBondContact O-N 3.42Å; I398-T402 PolarHBondContact O-OG1 3.07Å; E399-T402 PolarHBondContact O-N 3.29Å; T402-Q404 PolarHBondContact O-N 3.39Å; T402-I405 PolarHBondContact O-N 3.21Å; T402-V406 WeakPolarHBondContact O-CG2 3.32Å; T402-V406 PolarHBondContact O-N 3.25Å
403D98.6Very high98.4Very high1 Ų130.9 Ų30.91%0.00517%0.166CC..Hα-helixtrans-64.2-38.3178.4-171.886.4000112.9L47 E48 V49 E399 L401 V406 K407L47-D403 HydrophobicContact CB-CB 4.33Å; L47-D403 HydrophobicContact CD1-CB 4.45Å; L47-D403 HydrophobicContact CD2-CB 3.89Å; L47-D403 HydrophobicContact CG-CB 4.45Å; E48-D403 PolarHBondContact N-OD1 2.98Å; V49-D403 HydrophobicContact CG1-CB 4.44Å; V49-D403 HydrophobicContact CG2-CB 3.98Å; E399-D403 WeakPolarHBondContact O-CB 3.2Å; E399-D403 PolarHBondContact O-N 3.41Å; L401-D403 VanDerWaalsContact C-N 3.34Å; L401-D403 PolarHBondContact O-N 3.2Å; D403-V406 WeakPolarHBondContact O-CB 3.25Å; D403-V406 PolarHBondContact O-N 3.36Å; D403-K407 WeakPolarHBondContact O-CG 3.36Å; D403-K407 PolarHBondContact O-N 2.99Å; D403-K407 WeakPolarHBondContact OD2-CE 3.31Å; D403-K407 IonicContact OD2-NZ 3.75Å; D403-K407 PolarHBondContact OD2-NZ 3.05Å
404Q98.5Very high98.4Very high52 Ų5234.8 Ų34.824%0.24318%0.179CC..Hα-helixtrans-65.4-41.1174.6-7717793.700112.5I33 S400 L401 T402 V406 K407 Q408I33-Q404 HydrophobicContact CD1-CB 4.11Å; I33-Q404 HydrophobicContact CG1-CB 4.39Å; I33-Q404 HydrophobicContact CG2-CB 4.45Å; S400-Q404 VanDerWaalsContact O-CG 3.31Å; S400-Q404 WeakPolarHBondContact O-CG 3.31Å; S400-Q404 PolarHBondContact O-N 3.46Å; S400-Q404 VanDerWaalsContact O-N 3.12Å; S400-Q404 PolarHBondContact O-NE2 3.16Å; S400-Q404 VanDerWaalsContact O-NE2 3.15Å; L401-Q404 PolarHBondContact O-N 2.89Å; T402-Q404 PolarHBondContact O-N 3.39Å; Q404-V406 VanDerWaalsContact C-N 3.34Å; Q404-K407 PolarHBondContact O-N 3.26Å; Q404-Q408 WeakPolarHBondContact O-CG 3.23Å; Q404-Q408 PolarHBondContact O-N 2.9Å
405I98.8Very high98.4Very high0 Ų037 Ų370%018%0.178CC..Hα-helixtrans-62.3-43.2173.5-64.9172000110.2I33 V242 V245 M285 A288 M289 A292 L401 T402 K407 Q408 A409I33-I405 HydrophobicContact CD1-CG1 3.85Å; V242-I405 HydrophobicContact CG2-CB 4.4Å; V242-I405 HydrophobicContact CG2-CG1 4.15Å; V242-I405 HydrophobicContact CG2-CG2 4.18Å; V245-I405 HydrophobicContact CG2-CG2 4.33Å; M285-I405 HydrophobicContact SD-CD1 3.68Å; M285-I405 HydrophobicContact SD-CG1 4.11Å; A288-I405 HydrophobicContact CB-CD1 3.6Å; M289-I405 HydrophobicContact CB-CD1 4.35Å; A292-I405 HydrophobicContact CB-CB 3.94Å; A292-I405 HydrophobicContact CB-CG2 3.62Å; L401-I405 HydrophobicContact CG-CD1 4.49Å; L401-I405 WeakPolarHBondContact O-CG1 3.41Å; L401-I405 PolarHBondContact O-N 2.89Å; T402-I405 PolarHBondContact O-N 3.21Å; I405-K407 PolarHBondContact O-N 3.42Å; I405-Q408 PolarHBondContact O-N 3.3Å; I405-A409 WeakPolarHBondContact O-CB 3.41Å; I405-A409 PolarHBondContact O-N 3Å
406V98.7Very high98.4Very high0 Ų035 Ų350%016%0.163CC..Hα-helixtrans-54.4-51.1175.3166.80000110.7V49 A292 Y295 L296 T402 D403 Q404 R410V49-V406 HydrophobicContact CG1-CG2 3.92Å; A292-V406 HydrophobicContact CB-CG2 3.7Å; Y295-V406 HydrophobicContact CD1-CG1 3.92Å; Y295-V406 HydrophobicContact CD1-CG2 4.02Å; Y295-V406 HydrophobicContact CE1-CG1 4Å; Y295-V406 HydrophobicContact CG-CG2 4.29Å; L296-V406 HydrophobicContact CD2-CG1 3.93Å; L296-V406 HydrophobicContact CG-CG1 4.29Å; L296-V406 HydrophobicContact CG-CG2 4.35Å; T402-V406 WeakPolarHBondContact O-CG2 3.32Å; T402-V406 PolarHBondContact O-N 3.25Å; D403-V406 WeakPolarHBondContact O-CB 3.25Å; D403-V406 PolarHBondContact O-N 3.36Å; Q404-V406 VanDerWaalsContact C-N 3.34Å; V406-R410 WeakPolarHBondContact O-CB 3.31Å; V406-R410 PolarHBondContact O-N 3.38Å
407K98.4Very high98.3Very high101 Ų10133.8 Ų33.844%0.43916%0.164SC..Hα-helixtrans-60.9-47.4-179.4-74.2167.2174.8160.70112.7D403 Q404 I405 A411D403-K407 WeakPolarHBondContact O-CG 3.36Å; D403-K407 PolarHBondContact O-N 2.99Å; D403-K407 WeakPolarHBondContact OD2-CE 3.31Å; D403-K407 IonicContact OD2-NZ 3.75Å; D403-K407 PolarHBondContact OD2-NZ 3.05Å; Q404-K407 PolarHBondContact O-N 3.26Å; I405-K407 PolarHBondContact O-N 3.42Å; K407-A411 PolarHBondContact O-N 3.36Å
408Q98.4Very high98.2Very high54 Ų5438.1 Ų38.125%0.25219%0.186SC..Hα-helixtrans-72.6-40.2-177.3-65.1-173.56.400112.4E31 G32 I33 V242 Q404 I405 A411 I412E31-Q408 PolarHBondContact O-OE1 3.48Å; G32-Q408 PolarHBondContact O-NE2 3.39Å; G32-Q408 VanDerWaalsContact O-NE2 3.13Å; I33-Q408 VanDerWaalsContact CG1-NE2 3.28Å; V242-Q408 HydrophobicContact CG1-CB 3.62Å; V242-Q408 HydrophobicContact CG2-CB 4.13Å; Q404-Q408 WeakPolarHBondContact O-CG 3.23Å; Q404-Q408 PolarHBondContact O-N 2.9Å; I405-Q408 PolarHBondContact O-N 3.3Å; Q408-A411 WeakPolarHBondContact O-CB 3.49Å; Q408-A411 PolarHBondContact O-N 2.98Å; Q408-I412 PolarHBondContact O-N 2.85Å
409A98.7Very high98Very high0 Ų040 Ų400%020%0.202CC..Hα-helixtrans-66.3-39.4176.900000111.3V242 V245 A246 L296 I405 A411 I412 I413V242-A409 HydrophobicContact CG1-CB 4.37Å; V245-A409 HydrophobicContact CB-CB 4.14Å; V245-A409 HydrophobicContact CG1-CB 3.83Å; A246-A409 HydrophobicContact CB-CB 4.16Å; L296-A409 HydrophobicContact CD1-CB 3.74Å; I405-A409 WeakPolarHBondContact O-CB 3.41Å; I405-A409 PolarHBondContact O-N 3Å; A409-A411 VanDerWaalsContact C-N 3.29Å; A409-A411 PolarHBondContact O-N 2.91Å; A409-I412 PolarHBondContact O-N 3.39Å; A409-I413 WeakPolarHBondContact O-CG1 3.4Å; A409-I413 PolarHBondContact O-N 3.23Å
410R98.1Very high97.9Very high68 Ų6841.4 Ų41.426%0.25722%0.219SC..Hα-helixtrans-57.9-40.6173.2-169.8-176.4-75146-11.4111.6E48 L296 E299 V406 I413 Q414E48-R410 IonicContact OE1-NH1 2.78Å; E48-R410 PolarHBondContact OE1-NH1 3.18Å; E48-R410 IonicContact OE2-CZ 3.02Å; E48-R410 IonicContact OE2-NH1 3.46Å; E48-R410 PolarHBondContact OE2-NH1 3.4Å; E48-R410 IonicContact OE2-NH2 3.61Å; E48-R410 PolarHBondContact OE2-NH2 2.96Å; L296-R410 HydrophobicContact CD2-CB 4.26Å; E299-R410 IonicContact OE1-CZ 2.87Å; E299-R410 IonicContact OE1-NE 2.75Å; E299-R410 PolarHBondContact OE1-NE 2.99Å; E299-R410 IonicContact OE1-NH2 2.7Å; E299-R410 PolarHBondContact OE1-NH2 3.39Å; E299-R410 IonicContact OE2-CZ 2.85Å; E299-R410 IonicContact OE2-NE 3.88Å; E299-R410 IonicContact OE2-NH2 3.67Å; E299-R410 PolarHBondContact OE2-NH2 2.95Å; V406-R410 WeakPolarHBondContact O-CB 3.31Å; V406-R410 PolarHBondContact O-N 3.38Å; R410-I413 PolarHBondContact O-N 2.88Å; R410-Q414 WeakPolarHBondContact O-CB 3.48Å; R410-Q414 PolarHBondContact O-N 2.97Å
411A98.3Very high97.7Very high46 Ų4641.1 Ų41.138%0.3822%0.217SC..Hα-helixtrans-64.5-38.7176.400000113K407 Q408 A409 Q415K407-A411 PolarHBondContact O-N 3.36Å; Q408-A411 WeakPolarHBondContact O-CB 3.49Å; Q408-A411 PolarHBondContact O-N 2.98Å; A409-A411 VanDerWaalsContact C-N 3.29Å; A409-A411 PolarHBondContact O-N 2.91Å; A411-Q415 WeakPolarHBondContact O-CG 3.17Å; A411-Q415 PolarHBondContact O-N 2.64Å
412I98.3Very high97.5Very high18 Ų1841.1 Ų41.19%0.09222%0.217CC..Hα-helixtrans-70.2-42.5175.2-62.9176.8000110.9V242 Q243 A246 F247 Q408 A409 Q414 Q415 I416 M434V242-I412 HydrophobicContact CG1-CD1 3.81Å; Q243-I412 HydrophobicContact CG-CD1 4.15Å; A246-I412 HydrophobicContact CB-CB 3.56Å; A246-I412 HydrophobicContact CB-CD1 4.25Å; A246-I412 HydrophobicContact CB-CG1 4.48Å; A246-I412 HydrophobicContact CB-CG2 3.5Å; A246-I412 VanDerWaalsContact CB-CG2 3.5Å; F247-I412 HydrophobicContact CD1-CG2 4.1Å; F247-I412 HydrophobicContact CE1-CG2 3.56Å; F247-I412 HydrophobicContact CZ-CG2 4.35Å; Q408-I412 PolarHBondContact O-N 2.85Å; A409-I412 PolarHBondContact O-N 3.39Å; I412-Q414 VanDerWaalsContact C-N 3.27Å; I412-Q414 PolarHBondContact O-N 3.49Å; I412-Q415 WeakPolarHBondContact O-CB 3.46Å; I412-Q415 PolarHBondContact O-N 2.55Å; I412-Q415 VanDerWaalsContact O-N 3.15Å; I412-I416 HydrophobicContact CG2-CD1 4.03Å; I412-I416 WeakPolarHBondContact O-CG1 3.49Å; I412-I416 PolarHBondContact O-N 2.77Å; I412-I416 VanDerWaalsContact O-N 3.07Å; I412-M434 HydrophobicContact CD1-CE 4.14Å; I412-M434 HydrophobicContact CG1-CE 4.31Å; I412-M434 HydrophobicContact CG2-CE 4.31Å
413I98.4Very high97.2Very high22 Ų2242.1 Ų42.111%0.11323%0.225CC..Hα-helixtrans-58-42.8175.7-68.4165.7000110.2A246 L249 I253 A409 R410 Q415 I416 D417A246-I413 HydrophobicContact CB-CG1 4.06Å; L249-I413 HydrophobicContact CB-CD1 4.16Å; L249-I413 HydrophobicContact CD1-CD1 4.42Å; I253-I413 HydrophobicContact CD1-CG2 4.45Å; A409-I413 WeakPolarHBondContact O-CG1 3.4Å; A409-I413 PolarHBondContact O-N 3.23Å; R410-I413 PolarHBondContact O-N 2.88Å; I413-Q415 PolarHBondContact O-N 2.87Å; I413-I416 WeakPolarHBondContact O-CB 3.43Å; I413-I416 PolarHBondContact O-N 3.3Å; I413-I416 VanDerWaalsContact O-N 3.15Å; I413-D417 PolarHBondContact O-N 2.81Å
414Q97.8Very high96.9Very high111 Ų11147.9 Ų47.952%0.51925%0.25SC..Hα-helixtrans-60.1-44175.6-177.8179.4-5.900112.3R410 I412 I416 D417 E418R410-Q414 WeakPolarHBondContact O-CB 3.48Å; R410-Q414 PolarHBondContact O-N 2.97Å; I412-Q414 VanDerWaalsContact C-N 3.27Å; I412-Q414 PolarHBondContact O-N 3.49Å; Q414-I416 VanDerWaalsContact C-N 3.25Å; Q414-I416 PolarHBondContact O-N 3.41Å; Q414-D417 PolarHBondContact O-N 3.43Å; Q414-E418 HydrophobicContact CG-CG 4.41Å; Q414-E418 WeakPolarHBondContact CG-OE1 3.4Å; Q414-E418 PolarHBondContact NE2-OE1 3.02Å; Q414-E418 WeakPolarHBondContact O-CB 3.31Å; Q414-E418 VanDerWaalsContact O-CG 3.3Å; Q414-E418 WeakPolarHBondContact O-CG 3.49Å; Q414-E418 PolarHBondContact O-N 3.3Å
415Q97.5Very high96.6Very high91 Ų9145.4 Ų45.443%0.42524%0.238SC..Hα-helixtrans-60.2-36.5175.9-70174.433.600112.1A411 I412 I413 A419A411-Q415 WeakPolarHBondContact O-CG 3.17Å; A411-Q415 PolarHBondContact O-N 2.64Å; I412-Q415 WeakPolarHBondContact O-CB 3.46Å; I412-Q415 PolarHBondContact O-N 2.55Å; I412-Q415 VanDerWaalsContact O-N 3.15Å; I413-Q415 PolarHBondContact O-N 2.87Å; Q415-A419 PolarHBondContact O-N 3.49Å; Q415-A419 VanDerWaalsContact O-N 3.08Å
416I97.7Very high96.3Very high3 Ų346.3 Ų46.32%0.01524%0.243CC..Hα-helixtrans-69.7-43176.7-67.1162.3000111.2F247 A250 I412 I413 Q414 E418 A419 G420 G421 M422 A425F247-I416 HydrophobicContact CD1-CD1 3.65Å; F247-I416 HydrophobicContact CE1-CD1 3.99Å; A250-I416 HydrophobicContact CB-CD1 3.87Å; A250-I416 HydrophobicContact CB-CG2 4.06Å; I412-I416 HydrophobicContact CG2-CD1 4.03Å; I412-I416 WeakPolarHBondContact O-CG1 3.49Å; I412-I416 PolarHBondContact O-N 2.77Å; I412-I416 VanDerWaalsContact O-N 3.07Å; I413-I416 WeakPolarHBondContact O-CB 3.43Å; I413-I416 PolarHBondContact O-N 3.3Å; I413-I416 VanDerWaalsContact O-N 3.15Å; Q414-I416 VanDerWaalsContact C-N 3.25Å; Q414-I416 PolarHBondContact O-N 3.41Å; I416-E418 VanDerWaalsContact C-N 3.33Å; I416-E418 PolarHBondContact O-N 2.99Å; I416-A419 WeakPolarHBondContact O-CB 3.19Å; I416-A419 PolarHBondContact O-N 3.3Å; I416-G420 PolarHBondContact O-N 3.15Å; I416-G421 PolarHBondContact O-N 3.47Å; I416-M422 HydrophobicContact CD1-SD 4.02Å; I416-M422 HydrophobicContact CG1-SD 4.42Å; I416-M422 HydrophobicContact CG2-CB 3.99Å; I416-M422 HydrophobicContact CG2-SD 3.93Å; I416-A425 HydrophobicContact CG2-CB 4.13Å
417D96.2Very high95.8Very high77 Ų7752.8 Ų52.841%0.41227%0.273SS..Hα-helixtrans-63.5-39.3175.3-80.1-30.1000111.5K257 I413 Q414 A419 G420K257-D417 IonicContact NZ-OD1 2.85Å; I413-D417 PolarHBondContact O-N 2.81Å; Q414-D417 PolarHBondContact O-N 3.43Å; D417-A419 VanDerWaalsContact C-N 3.29Å; D417-A419 PolarHBondContact O-N 3.12Å; D417-G420 WeakPolarHBondContact O-CA 3.47Å; D417-G420 PolarHBondContact O-N 3Å
418E96.7Very high95.4Very high138 Ų13851.1 Ų51.165%0.64528%0.278SS*.Hα-helixtrans-63.7-31.9173.8-74.1171.8-173.300112.6Q414 I416 G420Q414-E418 HydrophobicContact CG-CG 4.41Å; Q414-E418 WeakPolarHBondContact CG-OE1 3.4Å; Q414-E418 PolarHBondContact NE2-OE1 3.02Å; Q414-E418 WeakPolarHBondContact O-CB 3.31Å; Q414-E418 VanDerWaalsContact O-CG 3.3Å; Q414-E418 WeakPolarHBondContact O-CG 3.49Å; Q414-E418 PolarHBondContact O-N 3.3Å; I416-E418 VanDerWaalsContact C-N 3.33Å; I416-E418 PolarHBondContact O-N 2.99Å; E418-G420 PolarHBondContact O-N 3.31Å
419A95Very high95Very high41 Ų4149.9 Ų49.934%0.33928%0.28SS..THydrogen-bonded Turntrans-74-3.6170.200000113.5Q415 I416 D417 K424 A425Q415-A419 PolarHBondContact O-N 3.49Å; Q415-A419 VanDerWaalsContact O-N 3.08Å; I416-A419 WeakPolarHBondContact O-CB 3.19Å; I416-A419 PolarHBondContact O-N 3.3Å; D417-A419 VanDerWaalsContact C-N 3.29Å; D417-A419 PolarHBondContact O-N 3.12Å; A419-K424 WeakPolarHBondContact O-CB 3.4Å; A419-A425 HydrophobicContact CB-CB 4.21Å
420G95.2Very high94.8Very high39 Ų3952 Ų5240%0.40229%0.291SS..THydrogen-bonded Turntrans93.923.817700000114.6I416 D417 E418I416-G420 PolarHBondContact O-N 3.15Å; D417-G420 WeakPolarHBondContact O-CA 3.47Å; D417-G420 PolarHBondContact O-N 3Å; E418-G420 PolarHBondContact O-N 3.31Å
421G94.8Very high94.7Very high1 Ų148.8 Ų48.81%0.0128%0.279CS..SBendtrans100.1167.2179.500000113I416 A423 K424 A425I416-G421 PolarHBondContact O-N 3.47Å; G421-A423 PolarHBondContact O-N 3.38Å; G421-K424 PolarHBondContact O-N 3.44Å; G421-A425 PolarHBondContact O-N 2.86Å
422M95.2Very high94.5Very high1 Ų148.8 Ų48.81%0.00527%0.27CS..Hα-helixtrans-66.1-36.9-167.4-167.749.4167.100113.1L194 F247 A250 D251 E254 I416 K424 A425 I426 P431L194-M422 HydrophobicContact CD1-CE 3.54Å; F247-M422 HydrophobicContact CB-CE 3.83Å; F247-M422 HydrophobicContact CD1-CE 4.26Å; F247-M422 HydrophobicContact CG-CE 4.28Å; A250-M422 HydrophobicContact CB-CB 4.19Å; A250-M422 HydrophobicContact CB-CG 4.18Å; A250-M422 HydrophobicContact CB-SD 4.26Å; D251-M422 WeakPolarHBondContact OD1-CE 3.37Å; D251-M422 WeakPolarHBondContact OD1-CG 3.21Å; E254-M422 HydrophobicContact CB-CB 4.34Å; I416-M422 HydrophobicContact CD1-SD 4.02Å; I416-M422 HydrophobicContact CG1-SD 4.42Å; I416-M422 HydrophobicContact CG2-CB 3.99Å; I416-M422 HydrophobicContact CG2-SD 3.93Å; M422-K424 PolarHBondContact O-N 3.42Å; M422-A425 PolarHBondContact O-N 2.82Å; M422-A425 HydrophobicContact SD-CB 4.46Å; M422-I426 HydrophobicContact CG-CD1 4.21Å; M422-I426 WeakPolarHBondContact O-CD1 3.35Å; M422-I426 VanDerWaalsContact O-CG1 3.27Å; M422-I426 WeakPolarHBondContact O-CG1 3.48Å; M422-I426 PolarHBondContact O-N 3.43Å; M422-P431 HydrophobicContact CE-CB 4.19Å; M422-P431 HydrophobicContact CE-CG 3.98Å; M422-P431 HydrophobicContact SD-CG 3.79Å
423A90.9Very high94.3Very high20 Ų2053.8 Ų53.817%0.16529%0.288CS..Hα-helixtrans-58.6-44.5175.100000112.4L190 E254 G421 I426 E427L190-A423 HydrophobicContact CD2-CB 4.44Å; E254-A423 HydrophobicContact CG-CB 4.26Å; G421-A423 PolarHBondContact O-N 3.38Å; A423-I426 PolarHBondContact O-N 3.25Å; A423-E427 PolarHBondContact O-N 3.28Å
424K92.4Very high94.2Very high123 Ų12354.4 Ų54.454%0.53529%0.291SS..Hα-helixtrans-71.4-36.7176.6-69.8-173.5-178.6174.70112.4A419 G421 M422 I426 E427 A428A419-K424 WeakPolarHBondContact O-CB 3.4Å; G421-K424 PolarHBondContact O-N 3.44Å; M422-K424 PolarHBondContact O-N 3.42Å; K424-I426 VanDerWaalsContact C-N 3.28Å; K424-I426 PolarHBondContact O-N 3.45Å; K424-E427 PolarHBondContact O-N 3.2Å; K424-A428 WeakPolarHBondContact O-CB 3.35Å; K424-A428 PolarHBondContact O-N 3.05Å
425A94Very high94.2Very high0 Ų049.4 Ų49.40%027%0.268CS..Hα-helixtrans-62.9-36.5175.700000111.9I416 A419 G421 M422 A428 G429 L430 P431I416-A425 HydrophobicContact CG2-CB 4.13Å; A419-A425 HydrophobicContact CB-CB 4.21Å; G421-A425 PolarHBondContact O-N 2.86Å; M422-A425 PolarHBondContact O-N 2.82Å; M422-A425 HydrophobicContact SD-CB 4.46Å; A425-A428 PolarHBondContact O-N 3.26Å; A425-G429 PolarHBondContact O-N 2.96Å; A425-G429 VanDerWaalsContact O-N 3.15Å; A425-L430 PolarHBondContact O-N 2.91Å; A425-P431 HydrophobicContact CB-CG 4.13Å; A425-P431 WeakPolarHBondContact O-CD 3.26Å
426I90.8Very high94.1Very high18 Ų1846.2 Ų46.29%0.09225%0.253CS..Hα-helixtrans-63.2-48.5172.6-72.2162.3000110.8L190 L194 M422 A423 K424 A428 G429L190-I426 HydrophobicContact CB-CD1 3.85Å; L190-I426 HydrophobicContact CD2-CD1 3.82Å; L190-I426 HydrophobicContact CG-CD1 4.36Å; L194-I426 HydrophobicContact CD1-CD1 4.35Å; L194-I426 HydrophobicContact CD1-CG1 4.29Å; L194-I426 HydrophobicContact CD2-CD1 4.46Å; L194-I426 HydrophobicContact CD2-CG1 3.66Å; L194-I426 HydrophobicContact CG-CD1 4.19Å; L194-I426 HydrophobicContact CG-CG1 3.92Å; M422-I426 HydrophobicContact CG-CD1 4.21Å; M422-I426 WeakPolarHBondContact O-CD1 3.35Å; M422-I426 VanDerWaalsContact O-CG1 3.27Å; M422-I426 WeakPolarHBondContact O-CG1 3.48Å; M422-I426 PolarHBondContact O-N 3.43Å; A423-I426 PolarHBondContact O-N 3.25Å; K424-I426 VanDerWaalsContact C-N 3.28Å; K424-I426 PolarHBondContact O-N 3.45Å; I426-A428 PolarHBondContact O-N 2.94Å; I426-G429 WeakPolarHBondContact O-CA 3.35Å; I426-G429 PolarHBondContact O-N 3.31Å
427E88.5Confident94.1Very high136 Ų13649.4 Ų49.464%0.63627%0.268SS*.Hα-helixtrans-59.4-35.8176.7-70.9175.517800112.2A423 K424 G429A423-E427 PolarHBondContact O-N 3.28Å; K424-E427 PolarHBondContact O-N 3.2Å; E427-G429 PolarHBondContact O-N 3.01Å
428A90Very high94.1Very high67 Ų6746.7 Ų46.755%0.55426%0.255SS*.THydrogen-bonded Turntrans-77.5-5.2174.500000114.2K424 A425 I426 L430K424-A428 WeakPolarHBondContact O-CB 3.35Å; K424-A428 PolarHBondContact O-N 3.05Å; A425-A428 PolarHBondContact O-N 3.26Å; I426-A428 PolarHBondContact O-N 2.94Å; A428-L430 VanDerWaalsContact C-N 3.26Å; A428-L430 PolarHBondContact O-N 3.19Å
429G91.2Very high94.1Very high27 Ų2740.2 Ų40.228%0.27823%0.226SC..THydrogen-bonded Turntrans68.118.1-179.900000114.8A425 I426 E427 R433A425-G429 PolarHBondContact O-N 2.96Å; A425-G429 VanDerWaalsContact O-N 3.15Å; I426-G429 WeakPolarHBondContact O-CA 3.35Å; I426-G429 PolarHBondContact O-N 3.31Å; E427-G429 PolarHBondContact O-N 3.01Å; G429-R433 VanDerWaalsContact O-CB 3.3Å; G429-R433 WeakPolarHBondContact O-CB 3.38Å; G429-R433 PolarHBondContact O-N 3.38Å
430L94Very high94.2Very high45 Ų4538.3 Ų38.324%0.23621%0.21CC..Hα-helixtrans-68.2-57.1-174.8172.167.9000112.3A425 A428 K432 R433 M434A425-L430 PolarHBondContact O-N 2.91Å; A428-L430 VanDerWaalsContact C-N 3.26Å; A428-L430 PolarHBondContact O-N 3.19Å; L430-K432 PolarHBondContact O-N 3.02Å; L430-R433 PolarHBondContact O-N 2.91Å; L430-M434 HydrophobicContact CD1-CG 4.42Å; L430-M434 HydrophobicContact CD1-SD 4.14Å; L430-M434 HydrophobicContact CG-SD 4.28Å; L430-M434 WeakPolarHBondContact O-CG 3.5Å; L430-M434 PolarHBondContact O-N 3.39Å
431P95.6Very high94.2Very high0 Ų041.2 Ų41.20%021%0.209CC..Hα-helixtrans-65.2-39.6-177.6-17.630.2000112.2L194 F247 M422 A425 R433 M434 I435L194-P431 HydrophobicContact CD1-CB 4.34Å; L194-P431 HydrophobicContact CD2-CB 3.79Å; L194-P431 HydrophobicContact CD2-CG 4.24Å; F247-P431 HydrophobicContact CD1-CB 3.99Å; F247-P431 HydrophobicContact CD2-CB 4.46Å; F247-P431 HydrophobicContact CE1-CB 3.79Å; F247-P431 HydrophobicContact CE1-CG 4.43Å; F247-P431 HydrophobicContact CE2-CB 4.28Å; F247-P431 HydrophobicContact CG-CB 4.34Å; F247-P431 HydrophobicContact CZ-CB 3.95Å; M422-P431 HydrophobicContact CE-CB 4.19Å; M422-P431 HydrophobicContact CE-CG 3.98Å; M422-P431 HydrophobicContact SD-CG 3.79Å; A425-P431 HydrophobicContact CB-CG 4.13Å; A425-P431 WeakPolarHBondContact O-CD 3.26Å; P431-R433 VanDerWaalsContact C-N 3.34Å; P431-R433 PolarHBondContact O-N 3.21Å; P431-M434 PolarHBondContact O-N 2.99Å; P431-I435 WeakPolarHBondContact O-CG1 3.37Å; P431-I435 PolarHBondContact O-N 3.34Å
432K93.7Very high94.2Very high47 Ų4742.9 Ų42.920%0.20422%0.216CC..Hα-helixtrans-58.5-45178.3-176.3167.9177.354.60111.6L194 L430 M434 I435 E436 D598L194-K432 HydrophobicContact CD2-CB 4.14Å; L194-K432 PolarHBondContact O-NZ 3.41Å; L430-K432 PolarHBondContact O-N 3.02Å; K432-M434 PolarHBondContact O-N 3.05Å; K432-I435 PolarHBondContact O-N 2.98Å; K432-E436 WeakPolarHBondContact CE-OE1 3.44Å; K432-E436 HydrophobicContact CG-CG 4.47Å; K432-E436 WeakPolarHBondContact CG-OE1 3.45Å; K432-E436 IonicContact NZ-OE1 2.97Å; K432-E436 PolarHBondContact NZ-OE1 3.31Å; K432-E436 WeakPolarHBondContact O-CG 3.46Å; K432-E436 PolarHBondContact O-N 3.37Å; K432-D598 IonicContact NZ-OD2 3.49Å; K432-D598 PolarHBondContact NZ-OD2 3.27Å
433R94.7Very high94.3Very high123 Ų12344.7 Ų44.746%0.46423%0.225SC..Hα-helixtrans-60.7-44.4175.7-168.7-167.1-37.7-178.57.3112.4G429 L430 P431 I435 E436 E437 V549G429-R433 VanDerWaalsContact O-CB 3.3Å; G429-R433 WeakPolarHBondContact O-CB 3.38Å; G429-R433 PolarHBondContact O-N 3.38Å; L430-R433 PolarHBondContact O-N 2.91Å; P431-R433 VanDerWaalsContact C-N 3.34Å; P431-R433 PolarHBondContact O-N 3.21Å; R433-I435 VanDerWaalsContact C-N 3.28Å; R433-I435 PolarHBondContact O-N 3.05Å; R433-E436 PolarHBondContact O-N 3.04Å; R433-E437 HydrophobicContact CG-CG 4.47Å; R433-E437 WeakPolarHBondContact O-CB 3.26Å; R433-E437 VanDerWaalsContact O-CG 3.3Å; R433-E437 WeakPolarHBondContact O-CG 3.36Å; R433-E437 PolarHBondContact O-N 3.39Å; R433-V549 HydrophobicContact CG-CG1 3.96Å
434M96.7Very high94.5Very high35 Ų3543.8 Ų43.817%0.17222%0.217CC..Hα-helixtrans-62-36178.2-66.8175.472.600112.6Q243 F247 I412 L430 P431 K432 A438Q243-M434 PolarHBondContact NE2-O 2.8Å; Q243-M434 VanDerWaalsContact NE2-O 3.15Å; F247-M434 HydrophobicContact CE1-SD 4.18Å; F247-M434 HydrophobicContact CZ-CB 4Å; F247-M434 HydrophobicContact CZ-CE 4.13Å; F247-M434 HydrophobicContact CZ-SD 3.87Å; I412-M434 HydrophobicContact CD1-CE 4.14Å; I412-M434 HydrophobicContact CG1-CE 4.31Å; I412-M434 HydrophobicContact CG2-CE 4.31Å; L430-M434 HydrophobicContact CD1-CG 4.42Å; L430-M434 HydrophobicContact CD1-SD 4.14Å; L430-M434 HydrophobicContact CG-SD 4.28Å; L430-M434 WeakPolarHBondContact O-CG 3.5Å; L430-M434 PolarHBondContact O-N 3.39Å; P431-M434 PolarHBondContact O-N 2.99Å; K432-M434 PolarHBondContact O-N 3.05Å; M434-A438 WeakPolarHBondContact O-CB 3.32Å; M434-A438 PolarHBondContact O-N 3.29Å
435I97.2Very high94.7Very high6 Ų639.2 Ų39.23%0.03120%0.198CC..Hα-helixtrans-68.9-47.3174.9-65.2172.5000110.3M234 A237 A239 F247 P431 K432 R433 E437 A438 S439M234-I435 HydrophobicContact CB-CD1 4.22Å; M234-I435 HydrophobicContact CG-CD1 4.46Å; A237-I435 HydrophobicContact CB-CG2 3.76Å; A239-I435 HydrophobicContact CB-CD1 4.46Å; A239-I435 HydrophobicContact CB-CG1 4.02Å; F247-I435 HydrophobicContact CD2-CD1 4.07Å; F247-I435 HydrophobicContact CD2-CG1 4.18Å; F247-I435 HydrophobicContact CE2-CD1 4.08Å; F247-I435 HydrophobicContact CE2-CG1 3.72Å; P431-I435 WeakPolarHBondContact O-CG1 3.37Å; P431-I435 PolarHBondContact O-N 3.34Å; K432-I435 PolarHBondContact O-N 2.98Å; R433-I435 VanDerWaalsContact C-N 3.28Å; R433-I435 PolarHBondContact O-N 3.05Å; I435-E437 PolarHBondContact O-N 2.85Å; I435-A438 PolarHBondContact O-N 3.5Å; I435-S439 WeakPolarHBondContact O-CB 3.5Å; I435-S439 PolarHBondContact O-N 3.21Å
436E96.1Very high94.8Very high23 Ų2339.7 Ų39.711%0.10720%0.201CC..Hα-helixtrans-64-39.7-179.9-72.4176.2-177.300112.1K432 R433 S439 A440 V549K432-E436 WeakPolarHBondContact CE-OE1 3.44Å; K432-E436 HydrophobicContact CG-CG 4.47Å; K432-E436 WeakPolarHBondContact CG-OE1 3.45Å; K432-E436 IonicContact NZ-OE1 2.97Å; K432-E436 PolarHBondContact NZ-OE1 3.31Å; K432-E436 WeakPolarHBondContact O-CG 3.46Å; K432-E436 PolarHBondContact O-N 3.37Å; R433-E436 PolarHBondContact O-N 3.04Å; E436-S439 PolarHBondContact O-N 2.79Å; E436-A440 WeakPolarHBondContact O-CB 3.07Å; E436-A440 PolarHBondContact O-N 2.73Å; E436-V549 HydrophobicContact CB-CG1 3.77Å; E436-V549 HydrophobicContact CB-CG2 4.12Å
437E96.5Very high95Very high71 Ų7140.6 Ų40.633%0.33221%0.206SC..Hα-helixtrans-62.5-42.8173.4-74.1175-171.200112.3R433 I435 R441 V549 V552R433-E437 HydrophobicContact CG-CG 4.47Å; R433-E437 WeakPolarHBondContact O-CB 3.26Å; R433-E437 VanDerWaalsContact O-CG 3.3Å; R433-E437 WeakPolarHBondContact O-CG 3.36Å; R433-E437 PolarHBondContact O-N 3.39Å; I435-E437 PolarHBondContact O-N 2.85Å; E437-R441 WeakPolarHBondContact O-CB 3.32Å; E437-R441 PolarHBondContact O-N 3.16Å; E437-R441 VanDerWaalsContact O-N 3.1Å; E437-V549 HydrophobicContact CG-CG1 4.04Å; E437-V552 HydrophobicContact CG-CG2 4.02Å
438A96.7Very high95.3Very high19 Ų1936.1 Ų36.116%0.15719%0.185CC..Hα-helixtrans-64.8-43.3176.300000111.3G238 M434 I435 R441 E442G238-A438 VanDerWaalsContact O-CB 3.26Å; G238-A438 WeakPolarHBondContact O-CB 3.42Å; M434-A438 WeakPolarHBondContact O-CB 3.32Å; M434-A438 PolarHBondContact O-N 3.29Å; I435-A438 PolarHBondContact O-N 3.5Å; A438-R441 PolarHBondContact O-N 3.32Å; A438-E442 WeakPolarHBondContact O-CB 3.18Å; A438-E442 PolarHBondContact O-N 3.34Å
439S96.8Very high95.5Very high3 Ų334.8 Ų34.82%0.02118%0.178CC..Hα-helixtrans-61-49.6177.8-158.30000112.7A237 I435 E436 R441 E442 Q443 R599A237-S439 WeakPolarHBondContact O-CB 3.39Å; A237-S439 PolarHBondContact O-OG 2.88Å; I435-S439 WeakPolarHBondContact O-CB 3.5Å; I435-S439 PolarHBondContact O-N 3.21Å; E436-S439 PolarHBondContact O-N 2.79Å; S439-R441 PolarHBondContact O-N 2.96Å; S439-E442 PolarHBondContact O-N 2.89Å; S439-Q443 PolarHBondContact O-N 3.37Å; S439-R599 WeakPolarHBondContact OG-CG 3.17Å; S439-R599 PolarHBondContact OG-NE 3.48Å
440A96.6Very high95.6Very high1 Ų138 Ų381%0.00818%0.184CC..Hα-helixtrans-63.9-39.7179.100000112E436 S444 V549 V552 I553E436-A440 WeakPolarHBondContact O-CB 3.07Å; E436-A440 PolarHBondContact O-N 2.73Å; A440-S444 WeakPolarHBondContact O-CB 3.31Å; A440-S444 PolarHBondContact O-N 3.21Å; A440-S444 VanDerWaalsContact O-N 3.09Å; A440-V549 HydrophobicContact CB-CG2 4.38Å; A440-V552 HydrophobicContact CB-CB 4.22Å; A440-V552 HydrophobicContact CB-CG1 3.93Å; A440-I553 HydrophobicContact CB-CG1 4.21Å
441R95.7Very high95.6Very high99 Ų9939 Ų3937%0.37419%0.185SC..Hα-helixtrans-65.4-45175.6-172.2175.7-77.2116.6-2.6111.4E437 A438 S439 S444 L445 V552E437-R441 WeakPolarHBondContact O-CB 3.32Å; E437-R441 PolarHBondContact O-N 3.16Å; E437-R441 VanDerWaalsContact O-N 3.1Å; A438-R441 PolarHBondContact O-N 3.32Å; S439-R441 PolarHBondContact O-N 2.96Å; R441-S444 PolarHBondContact O-N 3Å; R441-L445 WeakPolarHBondContact O-CG 3.1Å; R441-L445 PolarHBondContact O-N 3.41Å; R441-V552 HydrophobicContact CB-CG1 4.33Å
442E96Very high95.7Very high37 Ų3742.8 Ų42.817%0.17321%0.208CC..Hα-helixtrans-63.5-44.4179.2-172.162.1-164.200111.7W323 A438 S439 S444 L445 I446 R451W323-E442 HydrophobicContact CH2-CG 3.84Å; W323-E442 HydrophobicContact CZ2-CG 4.33Å; A438-E442 WeakPolarHBondContact O-CB 3.18Å; A438-E442 PolarHBondContact O-N 3.34Å; S439-E442 PolarHBondContact O-N 2.89Å; E442-S444 VanDerWaalsContact C-N 3.31Å; E442-S444 PolarHBondContact O-N 2.95Å; E442-L445 PolarHBondContact O-N 2.64Å; E442-L445 VanDerWaalsContact O-N 3.1Å; E442-I446 HydrophobicContact CG-CD1 4.16Å; E442-I446 WeakPolarHBondContact O-CG1 3.44Å; E442-I446 PolarHBondContact O-N 3Å; E442-R451 WeakPolarHBondContact OE1-CG 3.41Å; E442-R451 IonicContact OE1-NE 2.76Å; E442-R451 IonicContact OE2-NE 3.85Å
443Q96.7Very high96Very high39 Ų3942.4 Ų42.418%0.18221%0.208CC..Hα-helixtrans-58.2-45.1175.4-17165.945.700111.4S439 L445 I446 D447 V603S439-Q443 PolarHBondContact O-N 3.37Å; Q443-L445 VanDerWaalsContact C-N 3.28Å; Q443-L445 PolarHBondContact O-N 2.98Å; Q443-I446 PolarHBondContact O-N 2.84Å; Q443-I446 VanDerWaalsContact O-N 3.15Å; Q443-D447 PolarHBondContact NE2-OD1 3.15Å; Q443-D447 PolarHBondContact O-N 3.26Å; Q443-V603 HydrophobicContact CB-CG1 3.74Å; Q443-V603 HydrophobicContact CG-CG1 3.74Å
444S95.7Very high96.1Very high0 Ų039.5 Ų39.50%020%0.204CC..Hα-helixtrans-60.7-36.5177.2-1790000112.5A440 R441 E442 Q448 S556 Y557A440-S444 WeakPolarHBondContact O-CB 3.31Å; A440-S444 PolarHBondContact O-N 3.21Å; A440-S444 VanDerWaalsContact O-N 3.09Å; R441-S444 PolarHBondContact O-N 3Å; E442-S444 VanDerWaalsContact C-N 3.31Å; E442-S444 PolarHBondContact O-N 2.95Å; S444-Q448 WeakPolarHBondContact O-CB 3.43Å; S444-Q448 WeakPolarHBondContact O-CG 3.37Å; S444-Q448 PolarHBondContact O-N 3.01Å; S444-Q448 VanDerWaalsContact O-N 3.09Å; S444-Q448 PolarHBondContact O-NE2 3.02Å; S444-Q448 VanDerWaalsContact O-NE2 3.08Å; S444-Q448 PolarHBondContact OG-NE2 3.17Å; S444-S556 WeakPolarHBondContact CB-OG 3.49Å; S444-S556 WeakPolarHBondContact OG-CB 3.24Å; S444-S556 PolarHBondContact OG-OG 2.86Å; S444-Y557 VanDerWaalsContact OG-CD2 3.22Å; S444-Y557 WeakPolarHBondContact OG-CD2 3.3Å; S444-Y557 WeakPolarHBondContact OG-CE2 3.31Å
445L94.7Very high96.2Very high28 Ų2837.9 Ų37.915%0.14720%0.196CC..Hα-helixtrans-70.4-34.8175.9-65.5176.2000112.7R441 E442 Q443 G449 K450 R451R441-L445 WeakPolarHBondContact O-CG 3.1Å; R441-L445 PolarHBondContact O-N 3.41Å; E442-L445 PolarHBondContact O-N 2.64Å; E442-L445 VanDerWaalsContact O-N 3.1Å; Q443-L445 VanDerWaalsContact C-N 3.28Å; Q443-L445 PolarHBondContact O-N 2.98Å; L445-G449 PolarHBondContact O-N 3.4Å; L445-K450 HydrophobicContact CB-CB 4.35Å; L445-K450 HydrophobicContact CD2-CB 4.12Å; L445-K450 HydrophobicContact CD2-CD 3.65Å; L445-K450 WeakPolarHBondContact O-CA 3.44Å; L445-K450 WeakPolarHBondContact O-CB 3.38Å; L445-K450 PolarHBondContact O-N 3.25Å; L445-R451 HydrophobicContact CB-CB 4.36Å; L445-R451 HydrophobicContact CB-CG 3.67Å; L445-R451 HydrophobicContact CD1-CG 4.3Å; L445-R451 PolarHBondContact O-N 3.26Å
446I96.6Very high96.2Very high10 Ų1038.2 Ų38.25%0.05120%0.198CC..Hα-helixtrans-65.5-50.1174.9-69.1163000110.1W323 E442 Q443 Q448 G449 R451 I453 N457W323-I446 HydrophobicContact CH2-CD1 3.79Å; W323-I446 HydrophobicContact CZ2-CD1 3.59Å; E442-I446 HydrophobicContact CG-CD1 4.16Å; E442-I446 WeakPolarHBondContact O-CG1 3.44Å; E442-I446 PolarHBondContact O-N 3Å; Q443-I446 PolarHBondContact O-N 2.84Å; Q443-I446 VanDerWaalsContact O-N 3.15Å; I446-Q448 VanDerWaalsContact C-N 3.31Å; I446-Q448 PolarHBondContact O-N 2.87Å; I446-G449 WeakPolarHBondContact O-CA 3.31Å; I446-G449 PolarHBondContact O-N 3.44Å; I446-R451 HydrophobicContact CG1-CB 3.85Å; I446-I453 HydrophobicContact CD1-CD1 3.86Å; I446-I453 HydrophobicContact CG1-CD1 4Å; I446-I453 HydrophobicContact CG2-CD1 3.76Å; I446-I453 HydrophobicContact CG2-CG1 4.4Å; I446-N457 PolarHBondContact O-ND2 2.75Å
447D95.8Very high96.2Very high37 Ų3739.2 Ų39.220%0.19820%0.204CC..Hα-helixtrans-65.8-35.1-177.3-71.510.2000111.7Q443 G449 Y557 M698Q443-D447 PolarHBondContact NE2-OD1 3.15Å; Q443-D447 PolarHBondContact O-N 3.26Å; D447-G449 PolarHBondContact O-N 3.49Å; D447-Y557 VanDerWaalsContact CB-OH 3.29Å; D447-Y557 WeakPolarHBondContact CB-OH 3.43Å; D447-M698 WeakPolarHBondContact OD2-CB 3.49Å; D447-M698 PolarHBondContact OD2-N 3.17Å
448Q94.2Very high96.3Very high41 Ų4140.4 Ų40.419%0.19221%0.208CC..THydrogen-bonded Turntrans-72.1-5.2172.4-70.7175.76500113.8S444 I446 K450 S556 Y557S444-Q448 WeakPolarHBondContact O-CB 3.43Å; S444-Q448 WeakPolarHBondContact O-CG 3.37Å; S444-Q448 PolarHBondContact O-N 3.01Å; S444-Q448 VanDerWaalsContact O-N 3.09Å; S444-Q448 PolarHBondContact O-NE2 3.02Å; S444-Q448 VanDerWaalsContact O-NE2 3.08Å; S444-Q448 PolarHBondContact OG-NE2 3.17Å; I446-Q448 VanDerWaalsContact C-N 3.31Å; I446-Q448 PolarHBondContact O-N 2.87Å; Q448-K450 HydrophobicContact CB-CD 4.26Å; Q448-K450 HydrophobicContact CB-CG 4.11Å; Q448-K450 PolarHBondContact O-N 2.97Å; Q448-S556 PolarHBondContact NE2-OG 3.47Å; Q448-Y557 HydrophobicContact CG-CD1 4.16Å; Q448-Y557 HydrophobicContact CG-CE1 3.76Å
449G94.4Very high96.3Very high40 Ų4046.7 Ų46.741%0.41223%0.229SC..THydrogen-bonded Turntrans69.313.3-175.400000114.4L445 I446 D447L445-G449 PolarHBondContact O-N 3.4Å; I446-G449 WeakPolarHBondContact O-CA 3.31Å; I446-G449 PolarHBondContact O-N 3.44Å; D447-G449 PolarHBondContact O-N 3.49Å
450K93.4Very high96.3Very high94 Ų9452.6 Ų52.641%0.40925%0.254SS..SBendtrans-75.2-29.7175.2-67.6176.6177.11660111.3L445 Q448L445-K450 HydrophobicContact CB-CB 4.35Å; L445-K450 HydrophobicContact CD2-CB 4.12Å; L445-K450 HydrophobicContact CD2-CD 3.65Å; L445-K450 WeakPolarHBondContact O-CA 3.44Å; L445-K450 WeakPolarHBondContact O-CB 3.38Å; L445-K450 PolarHBondContact O-N 3.25Å; Q448-K450 HydrophobicContact CB-CD 4.26Å; Q448-K450 HydrophobicContact CB-CG 4.11Å; Q448-K450 PolarHBondContact O-N 2.97Å
451R94.7Very high96.3Very high66 Ų6656.1 Ų56.125%0.24927%0.273CS..SBendtrans-107117.5166.6-68.6-71.9-176.2-145.1-3.1108.1H27 E442 L445 I446 N457H27-R451 PolarHBondContact CE1-NH1 2.98Å; H27-R451 PolarHBondContact NE2-NH1 3.23Å; H27-R451 VanDerWaalsContact NE2-NH1 3.16Å; E442-R451 WeakPolarHBondContact OE1-CG 3.41Å; E442-R451 IonicContact OE1-NE 2.76Å; E442-R451 IonicContact OE2-NE 3.85Å; L445-R451 HydrophobicContact CB-CB 4.36Å; L445-R451 HydrophobicContact CB-CG 3.67Å; L445-R451 HydrophobicContact CD1-CG 4.3Å; L445-R451 PolarHBondContact O-N 3.26Å; I446-R451 HydrophobicContact CG1-CB 3.85Å; R451-N457 PolarHBondContact O-ND2 2.98Å
452V97.7Very high96.2Very high79 Ų7958.9 Ų58.948%0.47930%0.295SS..  trans-86.2129-176.8173.70000109.8V454 K458V452-V454 HydrophobicContact CG1-CG2 4.49Å; V452-K458 HydrophobicContact CG1-CB 3.94Å; V452-K458 HydrophobicContact CG1-CD 4Å; V452-K458 HydrophobicContact CG2-CD 4.18Å
453I98.4Very high96Very high39 Ų3965 Ų6520%0.232%0.323CS..  trans-120.1108.9167.5-55.6-178.5000107.2T326 I446 G455 V456 N457T326-I453 HydrophobicContact CG2-CG2 3.58Å; I446-I453 HydrophobicContact CD1-CD1 3.86Å; I446-I453 HydrophobicContact CG1-CD1 4Å; I446-I453 HydrophobicContact CG2-CD1 3.76Å; I446-I453 HydrophobicContact CG2-CG1 4.4Å; I453-G455 PolarHBondContact O-N 2.96Å; I453-V456 HydrophobicContact CB-CB 4.04Å; I453-V456 HydrophobicContact CB-CG2 4.35Å; I453-V456 HydrophobicContact CG2-CB 3.8Å; I453-V456 HydrophobicContact CG2-CG2 3.54Å; I453-V456 PolarHBondContact O-N 3.15Å; I453-V456 VanDerWaalsContact O-N 3.09Å; I453-N457 PolarHBondContact N-OD1 3.02Å; I453-N457 PolarHBondContact O-N 2.94Å; I453-N457 VanDerWaalsContact O-N 3.12Å; I453-N457 PolarHBondContact O-OD1 3.23Å
454V98.5Very high95.7Very high63 Ų6367 Ų6738%0.38233%0.332SS..BIsolated β-bridgetrans-60.3132.3179.7-179.90000110R336 V452 V456 K458 Y459R336-V454 PolarHBondContact NH2-O 3.06Å; V452-V454 HydrophobicContact CG1-CG2 4.49Å; V454-V456 VanDerWaalsContact C-N 3.25Å; V454-V456 PolarHBondContact O-N 3.09Å; V454-K458 WeakPolarHBondContact CA-O 3.18Å; V454-Y459 HydrophobicContact CG1-CD2 4.33Å; V454-Y459 HydrophobicContact CG2-CD2 4.27Å
455G97.4Very high95.4Very high1 Ų173.6 Ų73.61%0.0137%0.368CS..THydrogen-bonded Turntrans87.8-24.5-17500000113.7I453 K458I453-G455 PolarHBondContact O-N 2.96Å; G455-K458 PolarHBondContact N-O 3.5Å
456V97.2Very high95Very high12 Ų1281.9 Ų81.97%0.07341%0.405CS..THydrogen-bonded Turntrans-102.9-63-172.8-176.40000112.6T326 Q328 I453 V454 K460T326-V456 HydrophobicContact CG2-CG2 3.52Å; Q328-V456 HydrophobicContact CB-CG2 4.4Å; I453-V456 HydrophobicContact CB-CB 4.04Å; I453-V456 HydrophobicContact CB-CG2 4.35Å; I453-V456 HydrophobicContact CG2-CB 3.8Å; I453-V456 HydrophobicContact CG2-CG2 3.54Å; I453-V456 PolarHBondContact O-N 3.15Å; I453-V456 VanDerWaalsContact O-N 3.09Å; V454-V456 VanDerWaalsContact C-N 3.25Å; V454-V456 PolarHBondContact O-N 3.09Å; V456-K460 VanDerWaalsContact O-CD 3.27Å; V456-K460 WeakPolarHBondContact O-CD 3.46Å; V456-K460 WeakPolarHBondContact O-CE 3.17Å; V456-K460 PolarHBondContact O-NZ 3.47Å
457N97.1Very high94.4Very high44 Ų4482.8 Ų82.824%0.23541%0.412CS..THydrogen-bonded Turntrans-108.1-8.5-179.671.95.1000113.1I446 R451 I453I446-N457 PolarHBondContact O-ND2 2.75Å; R451-N457 PolarHBondContact O-ND2 2.98Å; I453-N457 PolarHBondContact N-OD1 3.02Å; I453-N457 PolarHBondContact O-N 2.94Å; I453-N457 VanDerWaalsContact O-N 3.12Å; I453-N457 PolarHBondContact O-OD1 3.23Å
458K97.9Very high94Very high96 Ų9688 Ų8842%0.41744%0.44SS..BIsolated β-bridgetrans-150.7145.3176-159.7178.6-179.3-170.30110.4V452 V454 G455 K460V452-K458 HydrophobicContact CG1-CB 3.94Å; V452-K458 HydrophobicContact CG1-CD 4Å; V452-K458 HydrophobicContact CG2-CD 4.18Å; V454-K458 WeakPolarHBondContact CA-O 3.18Å; G455-K458 PolarHBondContact N-O 3.5Å; K458-K460 VanDerWaalsContact C-N 3.31Å
459Y97.8Very high93.7Very high152 Ų15287.5 Ų87.560%0.59644%0.439SS*.SBendtrans58.743.1-175.9-43.5-75.6000112V454V454-Y459 HydrophobicContact CG1-CD2 4.33Å; V454-Y459 HydrophobicContact CG2-CD2 4.27Å
460K96.6Very high93.3Very high126 Ų12688.3 Ų88.355%0.54843%0.434SS..  trans-67.5147177.3-49.1-167.3-165.5-144.50110V456 K458V456-K460 VanDerWaalsContact O-CD 3.27Å; V456-K460 WeakPolarHBondContact O-CD 3.46Å; V456-K460 WeakPolarHBondContact O-CE 3.17Å; V456-K460 PolarHBondContact O-NZ 3.47Å; K458-K460 VanDerWaalsContact C-N 3.31Å
461L95.6Very high92.9Very high76 Ų7690.8 Ų90.840%0.39845%0.447SS..  trans-74.6152.9167.2-62.5176.5000109.7D329 H463D329-L461 HydrophobicContact CB-CD1 4.03Å; L461-H463 VanDerWaalsContact C-N 3.31Å; L461-H463 WeakPolarHBondContact CB-O 3.44Å
462D94.3Very high92.6Very high157 Ų15788.4 Ų88.484%0.8444%0.439SS*.SBendtrans-71.4-33.2171.5-67.8-32.4000110.7
463H91.7Very high92.2Very high164 Ų16488.7 Ų88.776%0.75944%0.438SS*.SBendtrans-143.5136.7176.4-59.6-65.5000109.7L461L461-H463 VanDerWaalsContact C-N 3.31Å; L461-H463 WeakPolarHBondContact CB-O 3.44Å
464E91Very high91.8Very high81 Ų8187.6 Ų87.638%0.37943%0.432SS..PPolyproline II helixtrans-83142.3173.3-61.7-64.1153.900110.3Q328 D329Q328-E464 WeakPolarHBondContact CB-OE1 3.38Å; D329-E464 PolarHBondContact N-OE2 3.07Å
465D88.7Confident91.4Very high140 Ų14088.6 Ų88.675%0.74944%0.438SS*.PPolyproline II helixtrans-78146172.2-71.4-37.7000110.7T467D465-T467 PolarHBondContact O-N 2.88Å
466E85.4Confident91.3Very high201 Ų20192.1 Ų92.194%0.93946%0.455SS*.PPolyproline II helixtrans-63.5133.3172.9-70.6-177.6-178.800110.7
467T85.5Confident91.1Very high30 Ų3091.6 Ų91.618%0.18445%0.452CS..  trans-118.3129.8176.6-61.20000109.3F357 L361 D465 V469F357-T467 HydrophobicContact CE2-CG2 4.08Å; L361-T467 HydrophobicContact CD1-CG2 3.76Å; D465-T467 PolarHBondContact O-N 2.88Å; T467-V469 PolarHBondContact O-N 2.89Å
468D86.3Confident91Very high147 Ų14793 Ų9379%0.78645%0.454SS*.  trans-63.3122.4175.8-68.7-34.7000110.6
469V87.2Confident90.9Very high30 Ų3092.9 Ų92.918%0.18246%0.458CS..  trans-113.8141.4177.4-175.30000109.8L361 T467 E471L361-V469 HydrophobicContact CB-CG2 3.79Å; T467-V469 PolarHBondContact O-N 2.89Å; V469-E471 PolarHBondContact O-N 3.31Å
470L86.7Confident90.9Very high57 Ų5790.7 Ų90.730%0.29845%0.453SS..  trans-68.9112.8174.1-176.365.2000110.8F81 L363F81-L470 HydrophobicContact CD1-CD2 4.32Å; F81-L470 HydrophobicContact CD2-CD2 3.99Å; F81-L470 HydrophobicContact CE1-CD2 4.33Å; F81-L470 HydrophobicContact CE2-CD2 4Å; F81-L470 HydrophobicContact CG-CD2 4.17Å; F81-L470 HydrophobicContact CZ-CD2 4.17Å; L363-L470 HydrophobicContact CB-CD2 4.11Å
471E86Confident90.9Very high146 Ų14685.2 Ų85.268%0.68243%0.429SS*.  trans-91.1129.5171.3-171.7169.9-161.500110.8V469 K649V469-E471 PolarHBondContact O-N 3.31Å; E471-K649 IonicContact OE1-NZ 3.73Å; E471-K649 PolarHBondContact OE1-NZ 2.97Å
472I87Confident91Very high16 Ų1683.3 Ų83.38%0.08242%0.42CS..  trans-108.1118.5175.8-62.1165.8000109.2F81 K127 L363 N474 V477F81-I472 HydrophobicContact CB-CD1 3.95Å; K127-I472 HydrophobicContact CD-CB 4.42Å; K127-I472 HydrophobicContact CD-CG2 4.49Å; K127-I472 PolarHBondContact NZ-O 3.08Å; K127-I472 WeakPolarHBondContact O-CD1 3.32Å; L363-I472 HydrophobicContact CD1-CD1 3.66Å; I472-N474 PolarHBondContact O-N 3.21Å; I472-N474 VanDerWaalsContact O-N 3.1Å; I472-V477 HydrophobicContact CG2-CG2 4.32Å
473D89.6Confident91.2Very high85 Ų8578.4 Ų78.446%0.45540%0.4SS..  trans-7693.1170.4-179.3-8.1000110V475 M476 V477D473-V475 PolarHBondContact O-N 3.09Å; D473-V475 WeakPolarHBondContact OD1-CB 3.19Å; D473-V475 PolarHBondContact OD1-N 3.39Å; D473-M476 HydrophobicContact CB-CB 4.19Å; D473-M476 HydrophobicContact CB-CE 4.13Å; D473-M476 PolarHBondContact O-N 3.27Å; D473-M476 PolarHBondContact OD1-N 3.36Å; D473-V477 WeakPolarHBondContact O-CG2 3.02Å; D473-V477 PolarHBondContact O-N 3.35Å
474N89.9Confident91.5Very high15 Ų1571.6 Ų71.68%0.0837%0.372CS..Hα-helixtrans-68.7-22.7-179.973.1-67.2000113A122 K127 I472 R478A122-N474 PolarHBondContact O-ND2 2.86Å; K127-N474 HydrophobicContact CD-CB 3.97Å; K127-N474 HydrophobicContact CG-CB 4.21Å; K127-N474 PolarHBondContact NZ-OD1 3.01Å; I472-N474 PolarHBondContact O-N 3.21Å; I472-N474 VanDerWaalsContact O-N 3.1Å; N474-R478 WeakPolarHBondContact O-CB 3.36Å; N474-R478 PolarHBondContact O-N 2.95Å
475V91Very high91.8Very high84 Ų8467.9 Ų67.951%0.50935%0.354SS..Hα-helixtrans-69.3-45.6179177.70000109D473 N479D473-V475 PolarHBondContact O-N 3.09Å; D473-V475 WeakPolarHBondContact OD1-CB 3.19Å; D473-V475 PolarHBondContact OD1-N 3.39Å; V475-N479 WeakPolarHBondContact O-CB 3.49Å; V475-N479 PolarHBondContact O-N 3.01Å; V475-N479 PolarHBondContact O-ND2 3.45Å; V475-N479 VanDerWaalsContact O-ND2 3.1Å
476M94Very high92.3Very high76 Ų7667.3 Ų67.337%0.37435%0.347SS..Hα-helixtrans-58.2-53.2172.3177-175.552.300111.3D473 R478 N479 E480D473-M476 HydrophobicContact CB-CB 4.19Å; D473-M476 HydrophobicContact CB-CE 4.13Å; D473-M476 PolarHBondContact O-N 3.27Å; D473-M476 PolarHBondContact OD1-N 3.36Å; M476-R478 VanDerWaalsContact C-N 3.35Å; M476-R478 PolarHBondContact O-N 3.16Å; M476-N479 PolarHBondContact O-N 2.93Å; M476-E480 PolarHBondContact O-N 2.96Å
477V94.4Very high92.9Very high0 Ų063.8 Ų63.80%033%0.325CS..Hα-helixtrans-58.5-46.9-177.11800000111.4S82 T83 V125 I472 D473 N479 E480 Q481S82-V477 WeakPolarHBondContact OG-CG2 3.36Å; T83-V477 HydrophobicContact CG2-CG1 4.11Å; T83-V477 HydrophobicContact CG2-CG2 4.11Å; V125-V477 HydrophobicContact CG1-CG1 4.19Å; I472-V477 HydrophobicContact CG2-CG2 4.32Å; D473-V477 WeakPolarHBondContact O-CG2 3.02Å; D473-V477 PolarHBondContact O-N 3.35Å; V477-N479 PolarHBondContact O-N 2.9Å; V477-E480 PolarHBondContact O-N 3.26Å; V477-Q481 WeakPolarHBondContact O-CG 3.45Å; V477-Q481 PolarHBondContact O-N 3.49Å
478R94.8Very high93.5Very high75 Ų7562.7 Ų62.728%0.28332%0.318SS..Hα-helixtrans-61.5-44178.8-178.5178.6173-149.4-3.2111.8V125 N474 M476 E480 Q481 I482V125-R478 HydrophobicContact CB-CB 4.26Å; V125-R478 HydrophobicContact CG1-CB 4.23Å; V125-R478 HydrophobicContact CG2-CG 4.38Å; N474-R478 WeakPolarHBondContact O-CB 3.36Å; N474-R478 PolarHBondContact O-N 2.95Å; M476-R478 VanDerWaalsContact C-N 3.35Å; M476-R478 PolarHBondContact O-N 3.16Å; R478-E480 VanDerWaalsContact C-N 3.34Å; R478-E480 PolarHBondContact O-N 3.32Å; R478-Q481 PolarHBondContact O-N 2.98Å; R478-I482 HydrophobicContact CG-CD1 3.77Å; R478-I482 HydrophobicContact CG-CG1 4.35Å; R478-I482 WeakPolarHBondContact O-CB 3.49Å; R478-I482 VanDerWaalsContact O-CG1 3.25Å; R478-I482 WeakPolarHBondContact O-CG1 3.12Å; R478-I482 PolarHBondContact O-N 3.08Å
479N96.2Very high94.1Very high93 Ų9359 Ų5950%0.49729%0.293SS..Hα-helixtrans-64.3-39.5178.8-71.1-24.1000112.1V475 M476 V477 A483V475-N479 WeakPolarHBondContact O-CB 3.49Å; V475-N479 PolarHBondContact O-N 3.01Å; V475-N479 PolarHBondContact O-ND2 3.45Å; V475-N479 VanDerWaalsContact O-ND2 3.1Å; M476-N479 PolarHBondContact O-N 2.93Å; V477-N479 PolarHBondContact O-N 2.9Å; N479-A483 WeakPolarHBondContact O-CB 3.36Å; N479-A483 PolarHBondContact O-N 2.88Å
480E96.3Very high94.6Very high106 Ų10661.7 Ų61.750%0.49532%0.318SS..Hα-helixtrans-63.2-43.4174.5-71.6-168.4175.900111.9M476 V477 R478 A483 S484M476-E480 PolarHBondContact O-N 2.96Å; V477-E480 PolarHBondContact O-N 3.26Å; R478-E480 VanDerWaalsContact C-N 3.34Å; R478-E480 PolarHBondContact O-N 3.32Å; E480-A483 PolarHBondContact O-N 3.43Å; E480-S484 PolarHBondContact O-N 3.46Å
481Q97.9Very high95.1Very high10 Ų1063.8 Ų63.85%0.04733%0.333CS..Hα-helixtrans-66.5-43.7178.3-71.7-63.59.700112.8S116 A131 D133 D137 V477 R478 A483 S484 L485S116-Q481 VanDerWaalsContact CB-CB 3.5Å; S116-Q481 WeakPolarHBondContact OG-CB 3.2Å; A131-Q481 HydrophobicContact CB-CG 3.96Å; A131-Q481 PolarHBondContact O-NE2 2.72Å; D133-Q481 PolarHBondContact OD2-OE1 3.04Å; D137-Q481 PolarHBondContact OD1-OE1 2.62Å; V477-Q481 WeakPolarHBondContact O-CG 3.45Å; V477-Q481 PolarHBondContact O-N 3.49Å; R478-Q481 PolarHBondContact O-N 2.98Å; Q481-A483 VanDerWaalsContact C-N 3.33Å; Q481-A483 PolarHBondContact O-N 3.24Å; Q481-S484 WeakPolarHBondContact O-CB 3.43Å; Q481-S484 PolarHBondContact O-N 3.26Å; Q481-S484 VanDerWaalsContact O-N 3.11Å; Q481-L485 PolarHBondContact O-N 2.95Å
482I98.1Very high95.7Very high37 Ų3758.9 Ų58.919%0.1931%0.309CS..Hα-helixtrans-58-46.7174.8-69.5170.4000110.3D117 R478 S484 L485 E486D117-I482 HydrophobicContact CB-CG1 3.85Å; R478-I482 HydrophobicContact CG-CD1 3.77Å; R478-I482 HydrophobicContact CG-CG1 4.35Å; R478-I482 WeakPolarHBondContact O-CB 3.49Å; R478-I482 VanDerWaalsContact O-CG1 3.25Å; R478-I482 WeakPolarHBondContact O-CG1 3.12Å; R478-I482 PolarHBondContact O-N 3.08Å; I482-S484 VanDerWaalsContact C-N 3.29Å; I482-S484 PolarHBondContact O-N 3.24Å; I482-L485 WeakPolarHBondContact O-CB 3.38Å; I482-L485 PolarHBondContact O-N 3.42Å; I482-E486 HydrophobicContact CG2-CG 4.38Å; I482-E486 WeakPolarHBondContact O-CG 3.14Å; I482-E486 PolarHBondContact O-N 2.86Å
483A98Very high96.2Very high53 Ų5363 Ų6344%0.43833%0.331SS..Hα-helixtrans-62.7-35.7177.600000112.5N479 E480 Q481 R487N479-A483 WeakPolarHBondContact O-CB 3.36Å; N479-A483 PolarHBondContact O-N 2.88Å; E480-A483 PolarHBondContact O-N 3.43Å; Q481-A483 VanDerWaalsContact C-N 3.33Å; Q481-A483 PolarHBondContact O-N 3.24Å; A483-R487 WeakPolarHBondContact O-CB 3.44Å; A483-R487 PolarHBondContact O-N 3.01Å; A483-R487 VanDerWaalsContact O-N 3.16Å
484S97.5Very high96.6Very high22 Ų2262.8 Ų62.815%0.15433%0.33CS..Hα-helixtrans-65.3-48173.9-166.30000111.5E480 Q481 I482 R487 I488E480-S484 PolarHBondContact O-N 3.46Å; Q481-S484 WeakPolarHBondContact O-CB 3.43Å; Q481-S484 PolarHBondContact O-N 3.26Å; Q481-S484 VanDerWaalsContact O-N 3.11Å; I482-S484 VanDerWaalsContact C-N 3.29Å; I482-S484 PolarHBondContact O-N 3.24Å; S484-R487 PolarHBondContact O-N 2.66Å; S484-I488 WeakPolarHBondContact O-CG1 3.2Å; S484-I488 PolarHBondContact O-N 3.29Å
485L98.4Very high97Very high2 Ų265.6 Ų65.61%0.0136%0.355CS..Hα-helixtrans-57.6-48.7176.3-82.7170.2000112.1D115 D117 D133 T134 Q481 I482 R487 I488 R489 T527D115-L485 HydrophobicContact CB-CD1 4.05Å; D117-L485 HydrophobicContact CB-CD1 4.07Å; D133-L485 HydrophobicContact CB-CD1 4.25Å; D133-L485 HydrophobicContact CB-CD2 3.8Å; D133-L485 HydrophobicContact CB-CG 4.07Å; T134-L485 HydrophobicContact CG2-CD2 4.24Å; Q481-L485 PolarHBondContact O-N 2.95Å; I482-L485 WeakPolarHBondContact O-CB 3.38Å; I482-L485 PolarHBondContact O-N 3.42Å; L485-R487 VanDerWaalsContact C-N 3.32Å; L485-R487 PolarHBondContact O-N 2.82Å; L485-I488 PolarHBondContact O-N 2.84Å; L485-R489 WeakPolarHBondContact O-CB 3.41Å; L485-R489 WeakPolarHBondContact O-CG 3.08Å; L485-R489 PolarHBondContact O-N 3.19Å; L485-T527 HydrophobicContact CD2-CG2 3.65Å
486E98.4Very high97.4Very high128 Ų12863 Ų6360%0.59834%0.342SS*.Hα-helixtrans-56.6-45.8176.8-75179.6166.500111.4I482 A490I482-E486 HydrophobicContact CG2-CG 4.38Å; I482-E486 WeakPolarHBondContact O-CG 3.14Å; I482-E486 PolarHBondContact O-N 2.86Å; E486-A490 VanDerWaalsContact O-CB 3.24Å; E486-A490 WeakPolarHBondContact O-CB 3.48Å; E486-A490 PolarHBondContact O-N 2.9Å
487R98.3Very high97.6Very high128 Ų12859.4 Ų59.448%0.48333%0.325SS..Hα-helixtrans-64-42.6177.5-178.4-17559.676.95.6112.2A483 S484 L485 A490 T491A483-R487 WeakPolarHBondContact O-CB 3.44Å; A483-R487 PolarHBondContact O-N 3.01Å; A483-R487 VanDerWaalsContact O-N 3.16Å; S484-R487 PolarHBondContact O-N 2.66Å; L485-R487 VanDerWaalsContact C-N 3.32Å; L485-R487 PolarHBondContact O-N 2.82Å; R487-A490 PolarHBondContact O-N 3.39Å; R487-T491 WeakPolarHBondContact O-CB 3.29Å; R487-T491 WeakPolarHBondContact O-CG2 3.15Å; R487-T491 PolarHBondContact O-N 3.06Å; R487-T491 PolarHBondContact O-OG1 2.82Å
488I98.1Very high97.8Very high6 Ų663.1 Ų63.13%0.03135%0.347CS..Hα-helixtrans-67.6-47.7-179.7-68.1-62000111.1T134 E136 S484 L485 A490 T491 R492 R525T134-I488 HydrophobicContact CG2-CG2 4.33Å; E136-I488 HydrophobicContact CB-CD1 4.5Å; E136-I488 HydrophobicContact CG-CD1 3.64Å; E136-I488 HydrophobicContact CG-CG1 4.44Å; S484-I488 WeakPolarHBondContact O-CG1 3.2Å; S484-I488 PolarHBondContact O-N 3.29Å; L485-I488 PolarHBondContact O-N 2.84Å; I488-A490 PolarHBondContact O-N 3.47Å; I488-T491 PolarHBondContact O-N 3.29Å; I488-T491 PolarHBondContact O-OG1 3.06Å; I488-R492 WeakPolarHBondContact O-CB 3.39Å; I488-R492 WeakPolarHBondContact O-CG 3.44Å; I488-R492 PolarHBondContact O-N 3.12Å; I488-R525 HydrophobicContact CG2-CB 3.94Å; I488-R525 HydrophobicContact CG2-CG 4.31Å
489R98.3Very high98Very high71 Ų7162.3 Ų62.327%0.26836%0.357SS..Hα-helixtrans-60.2-34.1175.7-66.8-179.7-172.3149.12.5111.5D115 D117 L485 T491D115-R489 IonicContact OD2-NH2 3.26Å; D115-R489 PolarHBondContact OD2-NH2 3.29Å; D117-R489 IonicContact OD1-NH2 3.72Å; D117-R489 PolarHBondContact OD1-NH2 2.97Å; D117-R489 IonicContact OD2-CZ 3.87Å; D117-R489 IonicContact OD2-NH1 3.85Å; D117-R489 PolarHBondContact OD2-NH1 3.33Å; D117-R489 IonicContact OD2-NH2 2.82Å; D117-R489 PolarHBondContact OD2-NH2 3.05Å; D117-R489 VanDerWaalsContact OD2-NH2 3.1Å; L485-R489 WeakPolarHBondContact O-CB 3.41Å; L485-R489 WeakPolarHBondContact O-CG 3.08Å; L485-R489 PolarHBondContact O-N 3.19Å; R489-T491 PolarHBondContact O-N 3.44Å
490A98Very high98.1Very high85 Ų8558 Ų5870%0.70233%0.334SS*.Hα-helixtrans-74.4-16.9176.200000115.3E486 R487 I488E486-A490 VanDerWaalsContact O-CB 3.24Å; E486-A490 WeakPolarHBondContact O-CB 3.48Å; E486-A490 PolarHBondContact O-N 2.9Å; R487-A490 PolarHBondContact O-N 3.39Å; I488-A490 PolarHBondContact O-N 3.47Å
491T97.4Very high98.2Very high101 Ų10154.2 Ų54.262%0.6232%0.317SS*.Hα-helixtrans-119.1-15.1-170.953.80000115.1R487 I488 R489R487-T491 WeakPolarHBondContact O-CB 3.29Å; R487-T491 WeakPolarHBondContact O-CG2 3.15Å; R487-T491 PolarHBondContact O-N 3.06Å; R487-T491 PolarHBondContact O-OG1 2.82Å; I488-T491 PolarHBondContact O-N 3.29Å; I488-T491 PolarHBondContact O-OG1 3.06Å; R489-T491 PolarHBondContact O-N 3.44Å
492R97.8Very high98.3Very high44 Ų4458.7 Ų58.717%0.16634%0.341CS..SBendtrans-78.5167.7178.472.9-170.4-172.2175-1.7112.5I488 D494 V497 R525 E530I488-R492 WeakPolarHBondContact O-CB 3.39Å; I488-R492 WeakPolarHBondContact O-CG 3.44Å; I488-R492 PolarHBondContact O-N 3.12Å; R492-D494 WeakPolarHBondContact CG-OD1 3.38Å; R492-D494 IonicContact CZ-OD1 3.29Å; R492-D494 IonicContact NE-OD1 2.87Å; R492-D494 PolarHBondContact NE-OD1 3.3Å; R492-D494 IonicContact NH2-OD1 3.45Å; R492-D494 PolarHBondContact O-N 3.5Å; R492-V497 HydrophobicContact CG-CG2 4.21Å; R492-R525 HydrophobicContact CB-CB 4.17Å; R492-R525 WeakPolarHBondContact CD-O 3.4Å; R492-R525 PolarHBondContact NH1-O 3.29Å; R492-E530 IonicContact CZ-OE1 3.34Å; R492-E530 IonicContact CZ-OE2 2.94Å; R492-E530 IonicContact NH1-OE1 2.74Å; R492-E530 PolarHBondContact NH1-OE1 2.79Å; R492-E530 IonicContact NH1-OE2 2.78Å; R492-E530 PolarHBondContact NH1-OE2 2.84Å; R492-E530 IonicContact NH2-OE1 2.91Å; R492-E530 PolarHBondContact NH2-OE1 3.23Å; R492-E530 IonicContact NH2-OE2 2.72Å
493D98.3Very high98.3Very high101 Ų10159 Ų5954%0.5435%0.349SS..  trans-85.195.5170.7-178.1-15.1000109.9A495 A496 V497D493-A495 PolarHBondContact O-N 3.24Å; D493-A495 WeakPolarHBondContact OD1-CB 3.42Å; D493-A495 PolarHBondContact OD1-N 3.02Å; D493-A496 HydrophobicContact CB-CB 3.9Å; D493-A496 PolarHBondContact O-N 3.34Å; D493-A496 VanDerWaalsContact O-N 3.15Å; D493-A496 PolarHBondContact OD1-N 2.99Å; D493-V497 WeakPolarHBondContact O-CG2 3.4Å; D493-V497 PolarHBondContact O-N 3.27Å
494D97.8Very high98.3Very high82 Ų8256.4 Ų56.444%0.43933%0.328SS..Hα-helixtrans-62.6-27.3-177.9-77.1-26.2000113.6R492 T498R492-D494 WeakPolarHBondContact CG-OD1 3.38Å; R492-D494 IonicContact CZ-OD1 3.29Å; R492-D494 IonicContact NE-OD1 2.87Å; R492-D494 PolarHBondContact NE-OD1 3.3Å; R492-D494 IonicContact NH2-OD1 3.45Å; R492-D494 PolarHBondContact O-N 3.5Å; D494-T498 WeakPolarHBondContact O-CB 3.46Å; D494-T498 PolarHBondContact O-N 3.24Å; D494-T498 PolarHBondContact O-OG1 2.81Å
495A98.5Very high98.4Very high73 Ų7356.3 Ų56.360%0.60333%0.327SS*.Hα-helixtrans-71.1-41.1176.100000110.6D493 T498 A499D493-A495 PolarHBondContact O-N 3.24Å; D493-A495 WeakPolarHBondContact OD1-CB 3.42Å; D493-A495 PolarHBondContact OD1-N 3.02Å; A495-T498 PolarHBondContact O-N 3.32Å; A495-A499 WeakPolarHBondContact O-CB 3.36Å; A495-A499 PolarHBondContact O-N 3.24Å
496A98.6Very high98.4Very high29 Ų2960 Ų6024%0.2434%0.344CS..Hα-helixtrans-65.3-40.6173.900000112.1D493 A499 A500 V524D493-A496 HydrophobicContact CB-CB 3.9Å; D493-A496 PolarHBondContact O-N 3.34Å; D493-A496 VanDerWaalsContact O-N 3.15Å; D493-A496 PolarHBondContact OD1-N 2.99Å; A496-A499 PolarHBondContact O-N 2.99Å; A496-A500 WeakPolarHBondContact O-CB 3.35Å; A496-A500 PolarHBondContact O-N 3.15Å; A496-V524 HydrophobicContact CB-CB 4.29Å; A496-V524 HydrophobicContact CB-CG1 4.05Å
497V98.8Very high98.3Very high2 Ų254 Ų541%0.01232%0.316CS..Hα-helixtrans-59.4-52.8173.9172.30000110.7R492 D493 A499 A500 L501 V524 A526R492-V497 HydrophobicContact CG-CG2 4.21Å; D493-V497 WeakPolarHBondContact O-CG2 3.4Å; D493-V497 PolarHBondContact O-N 3.27Å; V497-A499 VanDerWaalsContact C-N 3.28Å; V497-A499 PolarHBondContact O-N 3.06Å; V497-A500 PolarHBondContact O-N 3.35Å; V497-A500 VanDerWaalsContact O-N 3.08Å; V497-L501 HydrophobicContact CG1-CD1 3.75Å; V497-L501 HydrophobicContact CG1-CG 4.23Å; V497-L501 WeakPolarHBondContact O-CG 3.44Å; V497-L501 PolarHBondContact O-N 3.41Å; V497-V524 HydrophobicContact CG2-CB 4.32Å; V497-V524 HydrophobicContact CG2-CG2 4.08Å; V497-V524 WeakPolarHBondContact CG2-O 3.1Å; V497-A526 HydrophobicContact CG1-CB 4.11Å
498T98.6Very high98.3Very high77 Ų7748.1 Ų48.147%0.47230%0.295SS..Hα-helixtrans-57-43.2179.5-58.50000111.3D494 A495 N502D494-T498 WeakPolarHBondContact O-CB 3.46Å; D494-T498 PolarHBondContact O-N 3.24Å; D494-T498 PolarHBondContact O-OG1 2.81Å; A495-T498 PolarHBondContact O-N 3.32Å; T498-N502 WeakPolarHBondContact O-CB 3.42Å; T498-N502 PolarHBondContact O-N 3.19Å; T498-N502 PolarHBondContact O-ND2 2.98Å
499A98.7Very high98.2Very high59 Ų5953.1 Ų53.149%0.48832%0.318SS..Hα-helixtrans-63.8-41.7176.900000112.6A495 A496 V497 A503A495-A499 WeakPolarHBondContact O-CB 3.36Å; A495-A499 PolarHBondContact O-N 3.24Å; A496-A499 PolarHBondContact O-N 2.99Å; V497-A499 VanDerWaalsContact C-N 3.28Å; V497-A499 PolarHBondContact O-N 3.06Å; A499-A503 WeakPolarHBondContact O-CB 3.46Å; A499-A503 PolarHBondContact O-N 3.4Å
500A98.7Very high98.1Very high3 Ų354.8 Ų54.83%0.02533%0.329CS..Hα-helixtrans-68.6-40.7179.300000112.6A496 V497 A503 L504 A521 V524A496-A500 WeakPolarHBondContact O-CB 3.35Å; A496-A500 PolarHBondContact O-N 3.15Å; V497-A500 PolarHBondContact O-N 3.35Å; V497-A500 VanDerWaalsContact O-N 3.08Å; A500-A503 PolarHBondContact O-N 2.74Å; A500-L504 PolarHBondContact O-N 3.2Å; A500-A521 HydrophobicContact CB-CB 4.15Å; A500-V524 HydrophobicContact CB-CG2 3.71Å
501L98.7Very high97.6Very high26 Ų2657 Ų5714%0.13633%0.329CS..Hα-helixtrans-65.2-43.8175.5-65.9174.8000111.4V497 A503 L504 T505 A521 A526 E530 I531 A534V497-L501 HydrophobicContact CG1-CD1 3.75Å; V497-L501 HydrophobicContact CG1-CG 4.23Å; V497-L501 WeakPolarHBondContact O-CG 3.44Å; V497-L501 PolarHBondContact O-N 3.41Å; L501-A503 VanDerWaalsContact C-N 3.29Å; L501-A503 PolarHBondContact O-N 3.07Å; L501-L504 WeakPolarHBondContact O-CB 3.27Å; L501-L504 PolarHBondContact O-N 2.93Å; L501-L504 VanDerWaalsContact O-N 3.07Å; L501-T505 PolarHBondContact O-N 3.05Å; L501-T505 PolarHBondContact O-OG1 3.34Å; L501-A521 HydrophobicContact CD2-CB 4.46Å; L501-A526 HydrophobicContact CD2-CB 3.96Å; L501-A526 HydrophobicContact CG-CB 4.41Å; L501-E530 HydrophobicContact CD1-CB 3.85Å; L501-E530 HydrophobicContact CD1-CG 4.34Å; L501-E530 HydrophobicContact CD2-CB 4.1Å; L501-E530 WeakPolarHBondContact CD2-O 3.34Å; L501-I531 HydrophobicContact CD2-CG1 4.14Å; L501-A534 HydrophobicContact CB-CB 4.29Å; L501-A534 HydrophobicContact CD2-CB 4.12Å
502N98.5Very high97.5Very high103 Ų10356.8 Ų56.855%0.55132%0.321SS*.Hα-helixtrans-60.8-38.4174.2-73.9-24.6000112.1T498 L504 T505 H506T498-N502 WeakPolarHBondContact O-CB 3.42Å; T498-N502 PolarHBondContact O-N 3.19Å; T498-N502 PolarHBondContact O-ND2 2.98Å; N502-L504 VanDerWaalsContact C-N 3.33Å; N502-T505 PolarHBondContact O-N 3.27Å; N502-H506 WeakPolarHBondContact O-CB 3.36Å; N502-H506 PolarHBondContact O-N 2.54Å
503A98.5Very high97.5Very high43 Ų4356.7 Ų56.736%0.35532%0.324SS..Hα-helixtrans-65.7-36174.400000112A499 A500 L501 H506 A507A499-A503 WeakPolarHBondContact O-CB 3.46Å; A499-A503 PolarHBondContact O-N 3.4Å; A500-A503 PolarHBondContact O-N 2.74Å; L501-A503 VanDerWaalsContact C-N 3.29Å; L501-A503 PolarHBondContact O-N 3.07Å; A503-H506 PolarHBondContact O-N 3.33Å; A503-A507 WeakPolarHBondContact O-CB 3.46Å; A503-A507 PolarHBondContact O-N 2.93Å
504L98.5Very high97.5Very high0 Ų051.9 Ų51.90%030%0.298CS..Hα-helixtrans-66.8-44.5174.3-178.362.4000112A500 L501 N502 H506 A507 A508 L514 A517 I531 A534 L535A500-L504 PolarHBondContact O-N 3.2Å; L501-L504 WeakPolarHBondContact O-CB 3.27Å; L501-L504 PolarHBondContact O-N 2.93Å; L501-L504 VanDerWaalsContact O-N 3.07Å; N502-L504 VanDerWaalsContact C-N 3.33Å; L504-H506 VanDerWaalsContact C-N 3.32Å; L504-H506 PolarHBondContact O-N 3.37Å; L504-A507 WeakPolarHBondContact O-CB 3.24Å; L504-A507 PolarHBondContact O-N 3.21Å; L504-A508 PolarHBondContact O-N 3.07Å; L504-L514 HydrophobicContact CD1-CD2 4.17Å; L504-A517 HydrophobicContact CB-CB 4.23Å; L504-A517 HydrophobicContact CD1-CB 3.6Å; L504-I531 HydrophobicContact CD2-CB 4.39Å; L504-I531 HydrophobicContact CD2-CG2 3.68Å; L504-A534 HydrophobicContact CD2-CB 4.26Å; L504-L535 HydrophobicContact CD1-CD2 3.87Å; L504-L535 HydrophobicContact CD2-CD1 4.48Å; L504-L535 HydrophobicContact CD2-CD2 4.26Å; L504-L535 HydrophobicContact CD2-CG 4.05Å; L504-L535 HydrophobicContact CG-CD2 3.86Å; L504-L535 HydrophobicContact CG-CG 4.18Å
505T98.5Very high97.5Very high20 Ų2048 Ų4812%0.12328%0.277CS..Hα-helixtrans-61.2-42173.3-550000111.2L501 N502 A507 A508 Q509 A534 V537L501-T505 PolarHBondContact O-N 3.05Å; L501-T505 PolarHBondContact O-OG1 3.34Å; N502-T505 PolarHBondContact O-N 3.27Å; T505-A507 PolarHBondContact O-N 3.49Å; T505-A508 WeakPolarHBondContact O-CB 3.3Å; T505-A508 PolarHBondContact O-N 2.88Å; T505-Q509 WeakPolarHBondContact O-CG 3.47Å; T505-Q509 PolarHBondContact O-N 3.42Å; T505-Q509 VanDerWaalsContact O-N 3.09Å; T505-A534 PolarHBondContact OG1-O 3.5Å; T505-V537 HydrophobicContact CG2-CB 4.3Å; T505-V537 HydrophobicContact CG2-CG1 3.89Å
506H98.3Very high97.5Very high79 Ų7946.6 Ų46.637%0.36627%0.265SS..Hα-helixtrans-59.8-46.7174.3179.2-85.1000111.5N502 A503 L504 A508 Q509 H510 E512N502-H506 WeakPolarHBondContact O-CB 3.36Å; N502-H506 PolarHBondContact O-N 2.54Å; A503-H506 PolarHBondContact O-N 3.33Å; L504-H506 VanDerWaalsContact C-N 3.32Å; L504-H506 PolarHBondContact O-N 3.37Å; H506-A508 VanDerWaalsContact C-N 3.3Å; H506-A508 PolarHBondContact O-N 2.95Å; H506-Q509 PolarHBondContact O-N 3.21Å; H506-H510 AromaticContact CD2-CE1 3.56Å; H506-H510 AromaticContact CD2-ND1 3.38Å; H506-H510 PolarHBondContact CD2-ND1 3.04Å; H506-H510 AromaticContact CE1-CG 3.78Å; H506-H510 AromaticContact CE1-ND1 3.64Å; H506-H510 AromaticContact CG-ND1 3.66Å; H506-H510 AromaticContact ND1-ND1 3.82Å; H506-H510 AromaticContact NE2-CE1 3.64Å; H506-H510 AromaticContact NE2-CG 3.76Å; H506-H510 AromaticContact NE2-ND1 3.38Å; H506-H510 PolarHBondContact NE2-ND1 3.25Å; H506-H510 WeakPolarHBondContact O-CB 3.4Å; H506-H510 PolarHBondContact O-N 2.67Å; H506-H510 PolarHBondContact O-ND1 3.18Å; H506-E512 IonicContact CE1-OE1 3.73Å; H506-E512 PolarHBondContact CE1-OE1 3.1Å; H506-E512 IonicContact CE1-OE2 2.81Å; H506-E512 IonicContact ND1-OE1 3.26Å; H506-E512 IonicContact ND1-OE2 3.52Å; H506-E512 PolarHBondContact ND1-OE2 3.47Å; H506-E512 VanDerWaalsContact ND1-OE2 3.11Å
507A98.1Very high97.5Very high2 Ų246 Ų462%0.01726%0.261CS..Hα-helixtrans-58.5-44177.200000111.3R208 A503 L504 T505 Q509 H510 N511 E512 L514 A517R208-A507 PolarHBondContact NH2-O 2.84Å; A503-A507 WeakPolarHBondContact O-CB 3.46Å; A503-A507 PolarHBondContact O-N 2.93Å; L504-A507 WeakPolarHBondContact O-CB 3.24Å; L504-A507 PolarHBondContact O-N 3.21Å; T505-A507 PolarHBondContact O-N 3.49Å; A507-Q509 PolarHBondContact O-N 3.18Å; A507-H510 PolarHBondContact O-N 2.76Å; A507-N511 PolarHBondContact O-N 3.14Å; A507-E512 HydrophobicContact CB-CB 3.77Å; A507-E512 PolarHBondContact O-N 3.41Å; A507-L514 HydrophobicContact CB-CD2 4.02Å; A507-A517 HydrophobicContact CB-CB 4.24Å
508A97.6Very high97.5Very high5 Ų546 Ų464%0.04126%0.26CS..Hα-helixtrans-58.9-32.6174.700000113.2R208 L504 T505 H506 L514 L535 A538 F539R208-A508 PolarHBondContact NH1-O 2.79Å; L504-A508 PolarHBondContact O-N 3.07Å; T505-A508 WeakPolarHBondContact O-CB 3.3Å; T505-A508 PolarHBondContact O-N 2.88Å; H506-A508 VanDerWaalsContact C-N 3.3Å; H506-A508 PolarHBondContact O-N 2.95Å; A508-L514 HydrophobicContact CB-CD2 3.95Å; A508-L535 HydrophobicContact CB-CD2 4.06Å; A508-A538 HydrophobicContact CB-CB 3.59Å; A508-F539 HydrophobicContact CB-CE1 3.87Å; A508-F539 HydrophobicContact CB-CE2 4.14Å; A508-F539 HydrophobicContact CB-CZ 3.55Å
509Q96.3Very high97.5Very high111 Ų11142.4 Ų42.452%0.51924%0.238SC..Hα-helixtrans-86.1-25.5178.2-67.8170.1-10.500113.9T505 H506 A507 A538T505-Q509 WeakPolarHBondContact O-CG 3.47Å; T505-Q509 PolarHBondContact O-N 3.42Å; T505-Q509 VanDerWaalsContact O-N 3.09Å; H506-Q509 PolarHBondContact O-N 3.21Å; A507-Q509 PolarHBondContact O-N 3.18Å; Q509-A538 HydrophobicContact CG-CB 4.03Å
510H95.1Very high97.5Very high106 Ų10643 Ų4349%0.49123%0.234SC..Hα-helixtrans-119.318.1-167.8-59.688000115.4H506 A507 E512H506-H510 AromaticContact CD2-CE1 3.56Å; H506-H510 AromaticContact CD2-ND1 3.38Å; H506-H510 PolarHBondContact CD2-ND1 3.04Å; H506-H510 AromaticContact CE1-CG 3.78Å; H506-H510 AromaticContact CE1-ND1 3.64Å; H506-H510 AromaticContact CG-ND1 3.66Å; H506-H510 AromaticContact ND1-ND1 3.82Å; H506-H510 AromaticContact NE2-CE1 3.64Å; H506-H510 AromaticContact NE2-CG 3.76Å; H506-H510 AromaticContact NE2-ND1 3.38Å; H506-H510 PolarHBondContact NE2-ND1 3.25Å; H506-H510 WeakPolarHBondContact O-CB 3.4Å; H506-H510 PolarHBondContact O-N 2.67Å; H506-H510 PolarHBondContact O-ND1 3.18Å; A507-H510 PolarHBondContact O-N 2.76Å; H510-E512 VanDerWaalsContact C-N 3.27Å; H510-E512 PolarHBondContact O-N 3.04Å
511N87.6Confident97.5Very high132 Ų13242.9 Ų42.971%0.70623%0.233SC*.THydrogen-bonded Turntrans58.832.8177.9-64.2-33.3000114.6R208 A507R208-N511 PolarHBondContact NH1-OD1 3.49Å; R208-N511 VanDerWaalsContact NH2-CA 3.32Å; A507-N511 PolarHBondContact O-N 3.14Å
512E96.2Very high97.5Very high95 Ų9541.7 Ų41.744%0.44423%0.226SC..  trans-85.9159.3166.1-55170.8160.200109.6R208 H506 A507 H510 L514R208-E512 PolarHBondContact NH2-O 3.16Å; R208-E512 VanDerWaalsContact NH2-O 3.13Å; H506-E512 IonicContact CE1-OE1 3.73Å; H506-E512 PolarHBondContact CE1-OE1 3.1Å; H506-E512 IonicContact CE1-OE2 2.81Å; H506-E512 IonicContact ND1-OE1 3.26Å; H506-E512 IonicContact ND1-OE2 3.52Å; H506-E512 PolarHBondContact ND1-OE2 3.47Å; H506-E512 VanDerWaalsContact ND1-OE2 3.11Å; A507-E512 HydrophobicContact CB-CB 3.77Å; A507-E512 PolarHBondContact O-N 3.41Å; H510-E512 VanDerWaalsContact C-N 3.27Å; H510-E512 PolarHBondContact O-N 3.04Å; E512-L514 PolarHBondContact O-N 3.33Å
513N96.9Very high97.5Very high43 Ų4341.4 Ų41.423%0.2322%0.217CC..  trans-70.2117.2-174-173.5-87.5000112D212 L515 A516 A517D212-N513 PolarHBondContact O-ND2 3.49Å; N513-L515 PolarHBondContact O-N 3.25Å; N513-L515 PolarHBondContact OD1-N 3.4Å; N513-A516 HydrophobicContact CB-CB 4.3Å; N513-A516 PolarHBondContact O-N 3.29Å; N513-A516 PolarHBondContact OD1-N 3.4Å; N513-A517 PolarHBondContact O-N 2.9Å
514L98.5Very high97.5Very high0 Ų041.1 Ų41.10%021%0.211CC..Hα-helixtrans-68.7-35-174.2-63.7173.4000113.9L161 I209 D212 L504 A507 A508 E512 A517 A518 L535 F539L161-L514 HydrophobicContact CD1-CB 3.83Å; L161-L514 HydrophobicContact CD1-CD1 4.37Å; L161-L514 HydrophobicContact CD2-CB 4.13Å; I209-L514 HydrophobicContact CG1-CD1 3.7Å; D212-L514 HydrophobicContact CB-CB 4.48Å; D212-L514 VanDerWaalsContact OD2-CG 3.26Å; D212-L514 WeakPolarHBondContact OD2-CG 3.41Å; D212-L514 PolarHBondContact OD2-N 3.01Å; L504-L514 HydrophobicContact CD1-CD2 4.17Å; A507-L514 HydrophobicContact CB-CD2 4.02Å; A508-L514 HydrophobicContact CB-CD2 3.95Å; E512-L514 PolarHBondContact O-N 3.33Å; L514-A517 PolarHBondContact O-N 2.69Å; L514-A518 WeakPolarHBondContact O-CB 3.45Å; L514-A518 PolarHBondContact O-N 2.88Å; L514-L535 HydrophobicContact CD2-CD2 3.93Å; L514-F539 HydrophobicContact CD1-CE2 4.04Å; L514-F539 HydrophobicContact CD1-CZ 4.01Å
515L98.5Very high97.5Very high0 Ų043.5 Ų43.50%022%0.22CC..Hα-helixtrans-66.7-41.1178.9-178.159.5000111.1L161 L164 I168 I213 W216 N513 A517 A518 V519L161-L515 HydrophobicContact CD2-CB 3.92Å; L161-L515 HydrophobicContact CD2-CD1 4.14Å; L164-L515 HydrophobicContact CB-CD1 4.28Å; L164-L515 HydrophobicContact CD2-CD1 3.99Å; L164-L515 HydrophobicContact CD2-CD2 3.71Å; L164-L515 HydrophobicContact CG-CD1 4.08Å; L164-L515 HydrophobicContact CG-CD2 4.4Å; I168-L515 HydrophobicContact CD1-CD1 4.43Å; I168-L515 HydrophobicContact CD1-CD2 4.44Å; I213-L515 HydrophobicContact CG1-CB 4.39Å; I213-L515 HydrophobicContact CG1-CD2 4.31Å; W216-L515 HydrophobicContact CB-CB 4.35Å; W216-L515 HydrophobicContact CB-CD2 4.06Å; W216-L515 HydrophobicContact CD2-CD2 3.85Å; W216-L515 HydrophobicContact CD2-CG 4.26Å; W216-L515 HydrophobicContact CE3-CD2 3.53Å; W216-L515 HydrophobicContact CE3-CG 4.31Å; W216-L515 HydrophobicContact CG-CB 4.39Å; W216-L515 HydrophobicContact CG-CD2 4.08Å; W216-L515 HydrophobicContact CG-CG 4.37Å; W216-L515 HydrophobicContact CZ3-CD2 4.27Å; N513-L515 PolarHBondContact O-N 3.25Å; N513-L515 PolarHBondContact OD1-N 3.4Å; L515-A517 VanDerWaalsContact C-N 3.31Å; L515-A517 PolarHBondContact O-N 3.26Å; L515-A518 PolarHBondContact O-N 3.4Å; L515-V519 HydrophobicContact CD1-CG2 4.12Å; L515-V519 HydrophobicContact CG-CG2 4.33Å; L515-V519 VanDerWaalsContact O-CG2 3.24Å; L515-V519 WeakPolarHBondContact O-CG2 3.44Å; L515-V519 PolarHBondContact O-N 2.99Å
516A98.3Very high97.5Very high43 Ų4342.6 Ų42.636%0.35521%0.214SC..Hα-helixtrans-58.2-44175.700000112.1N513 N520N513-A516 HydrophobicContact CB-CB 4.3Å; N513-A516 PolarHBondContact O-N 3.29Å; N513-A516 PolarHBondContact OD1-N 3.4Å; A516-N520 PolarHBondContact O-N 3.04Å
517A98.6Very high97.6Very high18 Ų1838.8 Ų38.815%0.14920%0.197CC..Hα-helixtrans-67.6-41.7176.800000112.3L504 A507 N513 L514 L515 V519 N520 A521L504-A517 HydrophobicContact CB-CB 4.23Å; L504-A517 HydrophobicContact CD1-CB 3.6Å; A507-A517 HydrophobicContact CB-CB 4.24Å; N513-A517 PolarHBondContact O-N 2.9Å; L514-A517 PolarHBondContact O-N 2.69Å; L515-A517 VanDerWaalsContact C-N 3.31Å; L515-A517 PolarHBondContact O-N 3.26Å; A517-V519 PolarHBondContact O-N 3.43Å; A517-N520 WeakPolarHBondContact O-CB 3.41Å; A517-N520 PolarHBondContact O-N 2.97Å; A517-N520 VanDerWaalsContact O-N 3.16Å; A517-A521 PolarHBondContact O-N 3.28Å
518A98.8Very high97.6Very high0 Ų038.7 Ų38.70%020%0.196CC..Hα-helixtrans-63.9-39.517700000112.5L161 A165 L514 L515 N520 A521 A522 I531L161-A518 HydrophobicContact CB-CB 4.12Å; A165-A518 HydrophobicContact CB-CB 4.1Å; L514-A518 WeakPolarHBondContact O-CB 3.45Å; L514-A518 PolarHBondContact O-N 2.88Å; L515-A518 PolarHBondContact O-N 3.4Å; A518-N520 VanDerWaalsContact C-N 3.29Å; A518-N520 PolarHBondContact O-N 3.38Å; A518-A521 PolarHBondContact O-N 3.09Å; A518-A522 WeakPolarHBondContact O-CB 3.26Å; A518-A522 PolarHBondContact O-N 3.05Å; A518-I531 HydrophobicContact CB-CG2 4.42Å
519V98.7Very high97.6Very high2 Ų238.7 Ų38.71%0.01220%0.196CC..Hα-helixtrans-61.3-39.2173.5177.30000110.7A165 I168 V169 L515 A517 A522 R523A165-V519 HydrophobicContact CB-CB 4.47Å; A165-V519 HydrophobicContact CB-CG2 4Å; I168-V519 HydrophobicContact CB-CG2 4.46Å; I168-V519 HydrophobicContact CD1-CG2 3.85Å; I168-V519 HydrophobicContact CG2-CG1 4.14Å; I168-V519 HydrophobicContact CG2-CG2 4.39Å; V169-V519 HydrophobicContact CG2-CG1 3.95Å; L515-V519 HydrophobicContact CD1-CG2 4.12Å; L515-V519 HydrophobicContact CG-CG2 4.33Å; L515-V519 VanDerWaalsContact O-CG2 3.24Å; L515-V519 WeakPolarHBondContact O-CG2 3.44Å; L515-V519 PolarHBondContact O-N 2.99Å; A517-V519 PolarHBondContact O-N 3.43Å; V519-A522 PolarHBondContact O-N 2.95Å; V519-R523 VanDerWaalsContact CG1-CZ 3.44Å; V519-R523 VanDerWaalsContact CG1-NH2 3.34Å; V519-R523 WeakPolarHBondContact O-CG 3.31Å; V519-R523 PolarHBondContact O-N 3.19Å; V519-R523 VanDerWaalsContact O-N 3.1Å
520N98.6Very high97.8Very high73 Ų7335.3 Ų35.339%0.3918%0.18SC..Hα-helixtrans-64.4-44.4174.8-17042.2000112.2A516 A517 A518 A522 R523 V524A516-N520 PolarHBondContact O-N 3.04Å; A517-N520 WeakPolarHBondContact O-CB 3.41Å; A517-N520 PolarHBondContact O-N 2.97Å; A517-N520 VanDerWaalsContact O-N 3.16Å; A518-N520 VanDerWaalsContact C-N 3.29Å; A518-N520 PolarHBondContact O-N 3.38Å; N520-A522 VanDerWaalsContact C-N 3.34Å; N520-A522 PolarHBondContact O-N 3Å; N520-R523 PolarHBondContact O-N 2.67Å; N520-V524 PolarHBondContact O-N 3.08Å
521A98.8Very high97.9Very high0 Ų030.2 Ų30.20%016%0.157CC..Hα-helixtrans-60.2-42.3175.500000112.1A500 L501 A517 A518 R523 V524 R525 A526 I531A500-A521 HydrophobicContact CB-CB 4.15Å; L501-A521 HydrophobicContact CD2-CB 4.46Å; A517-A521 PolarHBondContact O-N 3.28Å; A518-A521 PolarHBondContact O-N 3.09Å; A521-R523 PolarHBondContact O-N 3.31Å; A521-V524 WeakPolarHBondContact O-CG2 3.35Å; A521-V524 PolarHBondContact O-N 2.92Å; A521-R525 PolarHBondContact O-N 2.9Å; A521-A526 HydrophobicContact CB-CB 3.94Å; A521-A526 VanDerWaalsContact O-CB 3.29Å; A521-A526 WeakPolarHBondContact O-CB 3.28Å; A521-A526 PolarHBondContact O-N 3.33Å; A521-I531 HydrophobicContact CB-CD1 3.96Å; A521-I531 HydrophobicContact CB-CG1 3.85Å
522A98.8Very high98.5Very high0 Ų024 Ų240%012%0.124CC..Hα-helixtrans-59.2-42.5174.600000113A165 F166 V169 A518 V519 N520 V524 R525A165-A522 HydrophobicContact CB-CB 3.85Å; F166-A522 HydrophobicContact CD1-CB 3.53Å; F166-A522 HydrophobicContact CE1-CB 3.78Å; V169-A522 HydrophobicContact CG2-CB 3.86Å; A518-A522 WeakPolarHBondContact O-CB 3.26Å; A518-A522 PolarHBondContact O-N 3.05Å; V519-A522 PolarHBondContact O-N 2.95Å; N520-A522 VanDerWaalsContact C-N 3.34Å; N520-A522 PolarHBondContact O-N 3Å; A522-V524 VanDerWaalsContact C-N 3.27Å; A522-V524 PolarHBondContact O-N 3.48Å; A522-R525 PolarHBondContact O-N 3.31Å
523R98.6Very high98.6Very high97 Ų9723.2 Ų23.237%0.36612%0.123SC..Hα-helixtrans-60.8-36179.3-73-174.4-168.7112-1.2112.7V169 E172 V519 N520 A521 R525V169-R523 HydrophobicContact CB-CG 4.46Å; V169-R523 HydrophobicContact CG1-CG 3.95Å; V169-R523 HydrophobicContact CG2-CG 3.56Å; E172-R523 VanDerWaalsContact CD-NH2 3.33Å; E172-R523 IonicContact OE1-CZ 2.7Å; E172-R523 IonicContact OE1-NH2 3.18Å; E172-R523 PolarHBondContact OE1-NH2 3.17Å; E172-R523 IonicContact OE2-CZ 3.82Å; E172-R523 IonicContact OE2-NE 3.94Å; E172-R523 PolarHBondContact OE2-NE 3.36Å; E172-R523 IonicContact OE2-NH2 3.86Å; E172-R523 PolarHBondContact OE2-NH2 3.38Å; V519-R523 VanDerWaalsContact CG1-CZ 3.44Å; V519-R523 VanDerWaalsContact CG1-NH2 3.34Å; V519-R523 WeakPolarHBondContact O-CG 3.31Å; V519-R523 PolarHBondContact O-N 3.19Å; V519-R523 VanDerWaalsContact O-N 3.1Å; N520-R523 PolarHBondContact O-N 2.67Å; A521-R523 PolarHBondContact O-N 3.31Å; R523-R525 VanDerWaalsContact C-N 3.27Å; R523-R525 WeakPolarHBondContact O-CD 3.44Å; R523-R525 PolarHBondContact O-N 2.87Å; R523-R525 PolarHBondContact O-NH1 3.5Å
524V98.7Very high98.6Very high37 Ų3721.6 Ų21.622%0.22412%0.115CC..THydrogen-bonded Turntrans-87.810.8178.5-58.90000113.4A496 V497 A500 N520 A521 A522 A526A496-V524 HydrophobicContact CB-CB 4.29Å; A496-V524 HydrophobicContact CB-CG1 4.05Å; V497-V524 HydrophobicContact CG2-CB 4.32Å; V497-V524 HydrophobicContact CG2-CG2 4.08Å; V497-V524 WeakPolarHBondContact CG2-O 3.1Å; A500-V524 HydrophobicContact CB-CG2 3.71Å; N520-V524 PolarHBondContact O-N 3.08Å; A521-V524 WeakPolarHBondContact O-CG2 3.35Å; A521-V524 PolarHBondContact O-N 2.92Å; A522-V524 VanDerWaalsContact C-N 3.27Å; A522-V524 PolarHBondContact O-N 3.48Å; V524-A526 VanDerWaalsContact C-N 3.35Å
525R98.7Very high98.6Very high51 Ų5121.6 Ų21.619%0.19212%0.115CC..THydrogen-bonded Turntrans63.336.9177.8-77.561.3178.6168.57.9113.1V135 E136 E173 I488 R492 A521 A522 R523V135-R525 HydrophobicContact CG1-CG 4.08Å; E136-R525 IonicContact OE1-CZ 3.87Å; E136-R525 VanDerWaalsContact OE1-CZ 3.28Å; E136-R525 IonicContact OE1-NE 3.02Å; E136-R525 PolarHBondContact OE1-NE 3.25Å; E136-R525 IonicContact OE1-NH2 3.34Å; E136-R525 PolarHBondContact OE1-NH2 2.98Å; E173-R525 VanDerWaalsContact CD-NH2 3.27Å; E173-R525 IonicContact OE1-CZ 2.97Å; E173-R525 IonicContact OE1-NH1 2.89Å; E173-R525 PolarHBondContact OE1-NH1 3.41Å; E173-R525 IonicContact OE1-NH2 3.95Å; E173-R525 PolarHBondContact OE1-NH2 3.42Å; E173-R525 IonicContact OE2-NH2 3.74Å; E173-R525 PolarHBondContact OE2-NH2 2.96Å; I488-R525 HydrophobicContact CG2-CB 3.94Å; I488-R525 HydrophobicContact CG2-CG 4.31Å; R492-R525 HydrophobicContact CB-CB 4.17Å; R492-R525 WeakPolarHBondContact CD-O 3.4Å; R492-R525 PolarHBondContact NH1-O 3.29Å; A521-R525 PolarHBondContact O-N 2.9Å; A522-R525 PolarHBondContact O-N 3.31Å; R523-R525 VanDerWaalsContact C-N 3.27Å; R523-R525 WeakPolarHBondContact O-CD 3.44Å; R523-R525 PolarHBondContact O-N 2.87Å; R523-R525 PolarHBondContact O-NH1 3.5Å
526A98.8Very high98.6Very high0 Ų024.4 Ų24.40%013%0.128CC..  trans-62.6143.1157.500000109.4V497 L501 A521 V524 E530 I531V497-A526 HydrophobicContact CG1-CB 4.11Å; L501-A526 HydrophobicContact CD2-CB 3.96Å; L501-A526 HydrophobicContact CG-CB 4.41Å; A521-A526 HydrophobicContact CB-CB 3.94Å; A521-A526 VanDerWaalsContact O-CB 3.29Å; A521-A526 WeakPolarHBondContact O-CB 3.28Å; A521-A526 PolarHBondContact O-N 3.33Å; V524-A526 VanDerWaalsContact C-N 3.35Å; A526-E530 WeakPolarHBondContact CA-OE2 3.29Å; A526-I531 HydrophobicContact CB-CD1 4.2Å; A526-I531 HydrophobicContact CB-CG1 3.94Å
527T98.9Very high98.5Very high0 Ų027.4 Ų27.40%014%0.142CC..  trans-79.9167.3178.573.40000111.6D115 D133 T134 L485 G529 E530 I531D115-T527 VanDerWaalsContact CG-OG1 3.28Å; D115-T527 VanDerWaalsContact OD1-CB 3.27Å; D115-T527 WeakPolarHBondContact OD1-CB 3.23Å; D115-T527 PolarHBondContact OD1-OG1 3.49Å; D115-T527 WeakPolarHBondContact OD2-CB 3.22Å; D115-T527 PolarHBondContact OD2-OG1 3.22Å; D133-T527 CarbonylContact O-C 3.6Å; D133-T527 VanDerWaalsContact O-CA 3.29Å; D133-T527 WeakPolarHBondContact O-CA 3.41Å; T134-T527 HydrophobicContact CG2-CG2 4.08Å; L485-T527 HydrophobicContact CD2-CG2 3.65Å; T527-G529 VanDerWaalsContact C-N 3.32Å; T527-E530 PolarHBondContact N-OE2 3.32Å; T527-E530 PolarHBondContact O-N 3.37Å; T527-E530 WeakPolarHBondContact OG1-CB 3.31Å; T527-E530 VanDerWaalsContact OG1-CG 3.23Å; T527-E530 WeakPolarHBondContact OG1-CG 3.41Å; T527-E530 PolarHBondContact OG1-N 3.16Å; T527-I531 VanDerWaalsContact O-CG1 3.3Å; T527-I531 WeakPolarHBondContact O-CG1 3.34Å; T527-I531 PolarHBondContact O-N 3.44Å
528L98.7Very high98.3Very high0 Ų028.2 Ų28.20%015%0.148CC..Hα-helixtrans-60.7-44.8176-177.8131.6000110.9T110 G113 D115 I132 D133 A159 P162 V163 F166 S532T110-L528 HydrophobicContact CG2-CD1 3.67Å; G113-L528 VanDerWaalsContact C-CD2 3.46Å; G113-L528 VanDerWaalsContact CA-CD2 3.45Å; D115-L528 PolarHBondContact OD1-N 3.4Å; I132-L528 WeakPolarHBondContact O-CD1 3.42Å; D133-L528 PolarHBondContact O-N 3.15Å; A159-L528 HydrophobicContact CB-CD1 4.3Å; A159-L528 HydrophobicContact CB-CD2 4.41Å; A159-L528 HydrophobicContact CB-CG 4.47Å; P162-L528 HydrophobicContact CB-CB 4.46Å; P162-L528 HydrophobicContact CB-CD1 4.23Å; P162-L528 HydrophobicContact CB-CG 4.1Å; P162-L528 HydrophobicContact CG-CD1 4.15Å; P162-L528 HydrophobicContact CG-CG 3.96Å; V163-L528 HydrophobicContact CG2-CD1 3.75Å; F166-L528 HydrophobicContact CE2-CB 3.94Å; F166-L528 HydrophobicContact CE2-CD1 4.26Å; F166-L528 HydrophobicContact CZ-CB 4.3Å; L528-S532 WeakPolarHBondContact O-CB 3.2Å; L528-S532 PolarHBondContact O-N 2.92Å; L528-S532 PolarHBondContact O-OG 2.98Å
529G98.7Very high98.1Very high4 Ų429.2 Ų29.24%0.04115%0.153CC..Hα-helixtrans-60.3-51.1174.400000111.5G113 D115 T527 I531 S532 D533G113-G529 WeakPolarHBondContact O-CA 3.32Å; D115-G529 WeakPolarHBondContact OD1-CA 3.43Å; D115-G529 PolarHBondContact OD1-N 3.38Å; T527-G529 VanDerWaalsContact C-N 3.32Å; G529-I531 VanDerWaalsContact C-N 3.35Å; G529-I531 PolarHBondContact O-N 3.23Å; G529-S532 CarbonylContact O-C 3.57Å; G529-S532 PolarHBondContact O-N 3.16Å; G529-D533 WeakPolarHBondContact O-CB 3.45Å; G529-D533 VanDerWaalsContact O-CG 3.28Å; G529-D533 PolarHBondContact O-N 3.29Å
530E98.8Very high98Very high40 Ų4034.7 Ų34.719%0.18718%0.182CC..Hα-helixtrans-59.3-42179.6-74.5168.316700113.1R492 L501 A526 T527 S532 A534R492-E530 IonicContact CZ-OE1 3.34Å; R492-E530 IonicContact CZ-OE2 2.94Å; R492-E530 IonicContact NH1-OE1 2.74Å; R492-E530 PolarHBondContact NH1-OE1 2.79Å; R492-E530 IonicContact NH1-OE2 2.78Å; R492-E530 PolarHBondContact NH1-OE2 2.84Å; R492-E530 IonicContact NH2-OE1 2.91Å; R492-E530 PolarHBondContact NH2-OE1 3.23Å; R492-E530 IonicContact NH2-OE2 2.72Å; L501-E530 HydrophobicContact CD1-CB 3.85Å; L501-E530 HydrophobicContact CD1-CG 4.34Å; L501-E530 HydrophobicContact CD2-CB 4.1Å; L501-E530 WeakPolarHBondContact CD2-O 3.34Å; A526-E530 WeakPolarHBondContact CA-OE2 3.29Å; T527-E530 PolarHBondContact N-OE2 3.32Å; T527-E530 PolarHBondContact O-N 3.37Å; T527-E530 WeakPolarHBondContact OG1-CB 3.31Å; T527-E530 VanDerWaalsContact OG1-CG 3.23Å; T527-E530 WeakPolarHBondContact OG1-CG 3.41Å; T527-E530 PolarHBondContact OG1-N 3.16Å; E530-S532 VanDerWaalsContact C-N 3.34Å; E530-A534 WeakPolarHBondContact O-CB 3.37Å; E530-A534 PolarHBondContact O-N 2.86Å
531I98.8Very high97.8Very high0 Ų033.3 Ų33.30%017%0.171CC..Hα-helixtrans-64.8-40.4175.9-70.2170000110.7P162 F166 L501 L504 A518 A521 A526 T527 G529 L535P162-I531 HydrophobicContact CB-CB 4.05Å; P162-I531 HydrophobicContact CB-CD1 3.99Å; P162-I531 HydrophobicContact CB-CG2 3.81Å; P162-I531 HydrophobicContact CG-CG2 4.08Å; F166-I531 HydrophobicContact CE1-CD1 3.96Å; F166-I531 HydrophobicContact CZ-CD1 4.14Å; L501-I531 HydrophobicContact CD2-CG1 4.14Å; L504-I531 HydrophobicContact CD2-CB 4.39Å; L504-I531 HydrophobicContact CD2-CG2 3.68Å; A518-I531 HydrophobicContact CB-CG2 4.42Å; A521-I531 HydrophobicContact CB-CD1 3.96Å; A521-I531 HydrophobicContact CB-CG1 3.85Å; A526-I531 HydrophobicContact CB-CD1 4.2Å; A526-I531 HydrophobicContact CB-CG1 3.94Å; T527-I531 VanDerWaalsContact O-CG1 3.3Å; T527-I531 WeakPolarHBondContact O-CG1 3.34Å; T527-I531 PolarHBondContact O-N 3.44Å; G529-I531 VanDerWaalsContact C-N 3.35Å; G529-I531 PolarHBondContact O-N 3.23Å; I531-L535 PolarHBondContact O-N 2.97Å
532S98.7Very high97.6Very high1 Ų136.1 Ų36.11%0.00718%0.182CC..Hα-helixtrans-70.4-44.4-179.8-56.20000111.4G113 Y201 L528 G529 E530 A534 L535 E536G113-S532 WeakPolarHBondContact CA-OG 3.43Å; Y201-S532 WeakPolarHBondContact OH-CA 3.46Å; Y201-S532 PolarHBondContact OH-O 3.42Å; L528-S532 WeakPolarHBondContact O-CB 3.2Å; L528-S532 PolarHBondContact O-N 2.92Å; L528-S532 PolarHBondContact O-OG 2.98Å; G529-S532 CarbonylContact O-C 3.57Å; G529-S532 PolarHBondContact O-N 3.16Å; E530-S532 VanDerWaalsContact C-N 3.34Å; S532-A534 VanDerWaalsContact C-N 3.33Å; S532-A534 PolarHBondContact O-N 3.15Å; S532-L535 WeakPolarHBondContact O-CB 3.27Å; S532-L535 PolarHBondContact O-N 3.45Å; S532-L535 VanDerWaalsContact O-N 3.13Å; S532-E536 PolarHBondContact O-N 3.49Å
533D98.3Very high96.8Very high79 Ų7941.8 Ų41.842%0.42221%0.212SC..Hα-helixtrans-61.7-39.8176.6-71.6-11.7000111.4G529 L535 E536 V537G529-D533 WeakPolarHBondContact O-CB 3.45Å; G529-D533 VanDerWaalsContact O-CG 3.28Å; G529-D533 PolarHBondContact O-N 3.29Å; D533-L535 PolarHBondContact O-N 3.4Å; D533-E536 WeakPolarHBondContact O-CB 3.26Å; D533-E536 PolarHBondContact O-N 3.45Å; D533-E536 VanDerWaalsContact O-N 3.11Å; D533-V537 WeakPolarHBondContact O-CG2 3.4Å; D533-V537 PolarHBondContact O-N 3.45Å
534A98.3Very high95.8Very high9 Ų939.8 Ų39.87%0.07421%0.211CC..Hα-helixtrans-61.5-30.2176.700000113.3L501 L504 T505 E530 S532L501-A534 HydrophobicContact CB-CB 4.29Å; L501-A534 HydrophobicContact CD2-CB 4.12Å; L504-A534 HydrophobicContact CD2-CB 4.26Å; T505-A534 PolarHBondContact OG1-O 3.5Å; E530-A534 WeakPolarHBondContact O-CB 3.37Å; E530-A534 PolarHBondContact O-N 2.86Å; S532-A534 VanDerWaalsContact C-N 3.33Å; S532-A534 PolarHBondContact O-N 3.15Å
535L98.3Very high94.5Very high0 Ų042.7 Ų42.70%023%0.23CC..Hα-helixtrans-81.3-38.1172.4-65.6167.8000111.6L161 Y201 L504 A508 L514 I531 S532 D533 V537 A538 F539L161-L535 HydrophobicContact CD1-CD1 3.51Å; L161-L535 HydrophobicContact CD1-CD2 4.43Å; Y201-L535 HydrophobicContact CE1-CB 3.84Å; Y201-L535 HydrophobicContact CE2-CD1 4.32Å; Y201-L535 WeakPolarHBondContact OH-CD1 3.46Å; L504-L535 HydrophobicContact CD1-CD2 3.87Å; L504-L535 HydrophobicContact CD2-CD1 4.48Å; L504-L535 HydrophobicContact CD2-CD2 4.26Å; L504-L535 HydrophobicContact CD2-CG 4.05Å; L504-L535 HydrophobicContact CG-CD2 3.86Å; L504-L535 HydrophobicContact CG-CG 4.18Å; A508-L535 HydrophobicContact CB-CD2 4.06Å; L514-L535 HydrophobicContact CD2-CD2 3.93Å; I531-L535 PolarHBondContact O-N 2.97Å; S532-L535 WeakPolarHBondContact O-CB 3.27Å; S532-L535 PolarHBondContact O-N 3.45Å; S532-L535 VanDerWaalsContact O-N 3.13Å; D533-L535 PolarHBondContact O-N 3.4Å; L535-V537 PolarHBondContact O-N 2.91Å; L535-A538 PolarHBondContact O-N 2.89Å; L535-F539 HydrophobicContact CB-CD2 4.21Å; L535-F539 HydrophobicContact CB-CE2 4.45Å; L535-F539 HydrophobicContact CD2-CE2 4.01Å; L535-F539 PolarHBondContact O-N 3.46Å
536E97.4Very high93.6Very high58 Ų5841.7 Ų41.727%0.27123%0.231SC..Hα-helixtrans-57.5-37.2176.8-172.4167.3152.400111.4Y201 S532 D533 A538 F539 D540 R541Y201-E536 HydrophobicContact CE1-CB 4.32Å; S532-E536 PolarHBondContact O-N 3.49Å; D533-E536 WeakPolarHBondContact O-CB 3.26Å; D533-E536 PolarHBondContact O-N 3.45Å; D533-E536 VanDerWaalsContact O-N 3.11Å; E536-A538 PolarHBondContact O-N 3.4Å; E536-A538 VanDerWaalsContact O-N 3.11Å; E536-F539 PolarHBondContact O-N 3.25Å; E536-D540 WeakPolarHBondContact O-CA 3.46Å; E536-D540 PolarHBondContact O-N 2.82Å; E536-R541 HydrophobicContact CG-CB 4.3Å; E536-R541 WeakPolarHBondContact OE2-CD 3.38Å; E536-R541 IonicContact OE2-NE 2.64Å
537V96.3Very high92.9Very high107 Ų10748.6 Ų48.665%0.64826%0.263SS*.Hα-helixtrans-53.6-31.6172.6171.50000113.1T505 D533 L535T505-V537 HydrophobicContact CG2-CB 4.3Å; T505-V537 HydrophobicContact CG2-CG1 3.89Å; D533-V537 WeakPolarHBondContact O-CG2 3.4Å; D533-V537 PolarHBondContact O-N 3.45Å; L535-V537 PolarHBondContact O-N 2.91Å
538A94.1Very high92.4Very high34 Ų3450.3 Ų50.328%0.28128%0.275SS..Hα-helixtrans-98.8-25.1-178.800000113.9A508 Q509 L535 E536A508-A538 HydrophobicContact CB-CB 3.59Å; Q509-A538 HydrophobicContact CG-CB 4.03Å; L535-A538 PolarHBondContact O-N 2.89Å; E536-A538 PolarHBondContact O-N 3.4Å; E536-A538 VanDerWaalsContact O-N 3.11Å
539F96Very high92.2Very high22 Ų2251 Ų5110%0.09628%0.279CS..Hα-helixtrans-117.4-14.3-167.2-62.1-25.3000115.1Y201 P202 P205 I209 A508 L514 L535 E536Y201-F539 HydrophobicContact CD1-CB 4.06Å; Y201-F539 HydrophobicContact CD1-CD2 4.33Å; Y201-F539 HydrophobicContact CG-CB 4.32Å; Y201-F539 HydrophobicContact CG-CD2 4.26Å; P202-F539 WeakPolarHBondContact CD-O 3.39Å; P202-F539 WeakPolarHBondContact CG-O 2.85Å; P205-F539 HydrophobicContact CB-CB 3.81Å; P205-F539 HydrophobicContact CB-CD1 3.57Å; P205-F539 HydrophobicContact CB-CD2 3.72Å; P205-F539 HydrophobicContact CB-CE1 4.01Å; P205-F539 HydrophobicContact CB-CE2 4.13Å; P205-F539 HydrophobicContact CB-CG 3.42Å; P205-F539 VanDerWaalsContact CB-CG 3.42Å; P205-F539 HydrophobicContact CB-CZ 4.27Å; P205-F539 HydrophobicContact CG-CB 3.93Å; P205-F539 HydrophobicContact CG-CD1 4.43Å; P205-F539 HydrophobicContact CG-CG 4.12Å; I209-F539 HydrophobicContact CD1-CE2 4.24Å; I209-F539 HydrophobicContact CG1-CE2 4.38Å; A508-F539 HydrophobicContact CB-CE1 3.87Å; A508-F539 HydrophobicContact CB-CE2 4.14Å; A508-F539 HydrophobicContact CB-CZ 3.55Å; L514-F539 HydrophobicContact CD1-CE2 4.04Å; L514-F539 HydrophobicContact CD1-CZ 4.01Å; L535-F539 HydrophobicContact CB-CD2 4.21Å; L535-F539 HydrophobicContact CB-CE2 4.45Å; L535-F539 HydrophobicContact CD2-CE2 4.01Å; L535-F539 PolarHBondContact O-N 3.46Å; E536-F539 PolarHBondContact O-N 3.25Å
540D95.5Very high91.9Very high117 Ų11755.1 Ų55.163%0.62630%0.303SS*.  trans60.1170.7-165.9-60.2-49.8000113.6P202 E536P202-D540 VanDerWaalsContact CD-O 3.31Å; P202-D540 WeakPolarHBondContact CD-O 3.44Å; E536-D540 WeakPolarHBondContact O-CA 3.46Å; E536-D540 PolarHBondContact O-N 2.82Å
541R95.3Very high91.8Very high43 Ų4354.9 Ų54.916%0.16231%0.312CS..  trans-100.9135.2174.1-153.1165.3-155.2-95.5-6.7111.1R112 Y114 I200 E536R112-R541 PolarHBondContact O-NH2 2.87Å; Y114-R541 VanDerWaalsContact CE2-NH2 3.27Å; Y114-R541 PolarHBondContact OH-NE 3.43Å; Y114-R541 PolarHBondContact OH-NH1 2.94Å; Y114-R541 PolarHBondContact OH-NH2 3.21Å; I200-R541 HydrophobicContact CG2-CG 4.28Å; I200-R541 CarbonylContact O-C 3.6Å; I200-R541 WeakPolarHBondContact O-CA 3.35Å; I200-R541 WeakPolarHBondContact O-CG 3.33Å; E536-R541 HydrophobicContact CG-CB 4.3Å; E536-R541 WeakPolarHBondContact OE2-CD 3.38Å; E536-R541 IonicContact OE2-NE 2.64Å
542Y93.3Very high91.6Very high59 Ų5955.4 Ų55.423%0.23132%0.315CS..  trans-86.1125.8-177.7-166.3-119.6000111.6Y193 Y199 I200 P202 V544Y193-Y542 AromaticContact CD1-CD1 3.7Å; Y193-Y542 HydrophobicContact CD1-CD1 3.7Å; Y193-Y542 AromaticContact CD1-CE1 3.57Å; Y193-Y542 HydrophobicContact CD1-CE1 3.57Å; Y193-Y542 AromaticContact CE1-CD1 3.51Å; Y193-Y542 HydrophobicContact CE1-CD1 3.51Å; Y193-Y542 AromaticContact CE1-CE1 3.78Å; Y193-Y542 HydrophobicContact CE1-CE1 3.78Å; Y193-Y542 HydrophobicContact CE1-CG 4.29Å; Y199-Y542 AromaticContact CD2-CD1 3.82Å; Y199-Y542 HydrophobicContact CD2-CD1 3.82Å; Y199-Y542 HydrophobicContact CD2-CG 4.49Å; Y199-Y542 AromaticContact CE2-CD1 3.79Å; Y199-Y542 HydrophobicContact CE2-CD1 3.79Å; Y199-Y542 WeakPolarHBondContact CE2-O 3.21Å; Y199-Y542 HydrophobicContact CG-CD1 4.36Å; I200-Y542 PolarHBondContact O-N 2.89Å; P202-Y542 HydrophobicContact CB-CD2 3.93Å; P202-Y542 HydrophobicContact CG-CD2 4.15Å; Y542-V544 HydrophobicContact CD1-CG2 3.71Å; Y542-V544 HydrophobicContact CE1-CG2 3.02Å; Y542-V544 HydrophobicContact CE2-CG2 4.15Å; Y542-V544 WeakPolarHBondContact OH-CG2 3.45Å
543L83.2Confident91.4Very high120 Ų12055.3 Ų55.363%0.62831%0.314SS*.  trans-132.5127.9174.4-63.8173.9000108.3F621L543-F621 HydrophobicContact CD2-CD2 4.35Å
544V76.3Confident91.3Very high55 Ų5552.4 Ų52.433%0.33330%0.301SS..  trans-116.6138.5-178.9-170.20000109.7Y542Y542-V544 HydrophobicContact CD1-CG2 3.71Å; Y542-V544 HydrophobicContact CE1-CG2 3.02Å; Y542-V544 HydrophobicContact CE2-CG2 4.15Å; Y542-V544 WeakPolarHBondContact OH-CG2 3.45Å
545P73.1Confident91.2Very high97 Ų9757.6 Ų57.663%0.6332%0.324SS*.  trans-61.5138.6169.525.5-33.9000111.3
546S78.6Confident91Very high30 Ų3057.6 Ų57.621%0.2132%0.324CS..  trans-77.4122.9175-74.10000110.8S618S546-S618 WeakPolarHBondContact CB-O 3.48Å; S546-S618 PolarHBondContact OG-O 2.92Å
547Q83.9Confident90.8Very high146 Ų14655 Ų5568%0.68231%0.312SS*.  trans-122.9158.3169.3-63.8-179.9-6.600110.6K602Q547-K602 VanDerWaalsContact O-CD 3.24Å; Q547-K602 WeakPolarHBondContact O-CD 3.32Å; Q547-K602 WeakPolarHBondContact O-CE 3.36Å; Q547-K602 PolarHBondContact O-NZ 2.76Å
548C89.2Confident90.8Very high35 Ų3554.3 Ų54.324%0.23630%0.301CS..  trans-129.7161.3171.661.20000110.8K602 A605 L617C548-K602 HydrophobicContact CB-CD 4.13Å; C548-A605 HydrophobicContact CB-CB 4.09Å; C548-L617 HydrophobicContact CB-CD1 4.06Å
549V93.7Very high90.7Very high15 Ų1558.5 Ų58.59%0.09132%0.315CS..  trans-73.9148.9170.6-63.40000110.7R433 E436 E437 A440 V552 S606R433-V549 HydrophobicContact CG-CG1 3.96Å; E436-V549 HydrophobicContact CB-CG1 3.77Å; E436-V549 HydrophobicContact CB-CG2 4.12Å; E437-V549 HydrophobicContact CG-CG1 4.04Å; A440-V549 HydrophobicContact CB-CG2 4.38Å; V549-V552 HydrophobicContact CB-CG2 4.24Å; V549-V552 HydrophobicContact CG2-CG2 4.16Å; V549-S606 WeakPolarHBondContact O-CB 3.5Å; V549-S606 PolarHBondContact O-OG 3.31Å
550T93.1Very high90.5Very high90 Ų9059.6 Ų59.655%0.55233%0.326SS*.  trans-130.6150.2178.658.90000110.3V552T550-V552 VanDerWaalsContact C-N 3.29Å; T550-V552 PolarHBondContact O-N 3.4Å
551G95.3Very high90.3Very high35 Ų3562.6 Ų62.636%0.36134%0.336SS..SBendtrans84.3-9.217700000115Q555 D610G551-Q555 WeakPolarHBondContact O-CB 3.09Å; G551-Q555 PolarHBondContact O-N 3.04Å; G551-D610 WeakPolarHBondContact CA-OD1 3.46Å; G551-D610 WeakPolarHBondContact CA-OD2 3.39Å; G551-D610 PolarHBondContact N-OD1 2.85Å; G551-D610 PolarHBondContact N-OD2 3.4Å
552V95.1Very high90.1Very high11 Ų1168.8 Ų68.87%0.06736%0.364CS..Hα-helixtrans-72.2-40.6-176.4-177.30000111.2E437 A440 R441 V549 T550 S556 D610E437-V552 HydrophobicContact CG-CG2 4.02Å; A440-V552 HydrophobicContact CB-CB 4.22Å; A440-V552 HydrophobicContact CB-CG1 3.93Å; R441-V552 HydrophobicContact CB-CG1 4.33Å; V549-V552 HydrophobicContact CB-CG2 4.24Å; V549-V552 HydrophobicContact CG2-CG2 4.16Å; T550-V552 VanDerWaalsContact C-N 3.29Å; T550-V552 PolarHBondContact O-N 3.4Å; V552-S556 PolarHBondContact O-N 2.98Å; V552-S556 VanDerWaalsContact O-N 3.15Å; V552-D610 PolarHBondContact N-OD2 3.03Å
553I95.5Very high90Very high0 Ų066.3 Ų66.30%036%0.356CS..Hα-helixtrans-72.8-48.6-178.6-71.6164.6000109A440 Q555 S556 Y557 F567 A607 D610 M698A440-I553 HydrophobicContact CB-CG1 4.21Å; I553-Q555 VanDerWaalsContact C-N 3.33Å; I553-Q555 PolarHBondContact O-N 2.78Å; I553-S556 WeakPolarHBondContact O-CB 3.28Å; I553-S556 PolarHBondContact O-N 2.86Å; I553-Y557 HydrophobicContact CG2-CD2 3.79Å; I553-Y557 HydrophobicContact CG2-CE2 3.91Å; I553-Y557 WeakPolarHBondContact O-CD2 3.22Å; I553-Y557 PolarHBondContact O-N 2.64Å; I553-F567 HydrophobicContact CG2-CE2 4.11Å; I553-A607 VanDerWaalsContact CD1-CA 3.49Å; I553-A607 HydrophobicContact CD1-CB 3.67Å; I553-A607 VanDerWaalsContact CD1-N 3.33Å; I553-D610 WeakPolarHBondContact CB-OD2 3.44Å; I553-D610 PolarHBondContact N-OD2 3.5Å; I553-D610 VanDerWaalsContact N-OD2 3.11Å; I553-M698 HydrophobicContact CB-CE 4.39Å; I553-M698 HydrophobicContact CD1-CE 3.77Å; I553-M698 HydrophobicContact CD1-SD 3.66Å; I553-M698 HydrophobicContact CG1-CE 4.07Å; I553-M698 HydrophobicContact CG2-CE 3.44Å; I553-M698 VanDerWaalsContact CG2-CE 3.44Å
554A95.8Very high90.6Very high18 Ų1861.2 Ų61.215%0.14933%0.331CS..Hα-helixtrans-52.5-52174.200000110.9S556 Y557 H558 F567 D610A554-S556 PolarHBondContact O-N 3.42Å; A554-S556 VanDerWaalsContact O-N 3.16Å; A554-Y557 PolarHBondContact O-N 2.97Å; A554-Y557 VanDerWaalsContact O-N 3.13Å; A554-H558 PolarHBondContact O-N 3.24Å; A554-H558 PolarHBondContact O-ND1 2.69Å; A554-F567 HydrophobicContact CB-CE1 4.16Å; A554-F567 HydrophobicContact CB-CE2 4.42Å; A554-F567 HydrophobicContact CB-CZ 3.8Å; A554-D610 HydrophobicContact CB-CB 4.22Å; A554-D610 PolarHBondContact N-OD2 3.22Å
555Q95.5Very high91.5Very high117 Ų11762.1 Ų62.155%0.54734%0.34SS..Hα-helixtrans-55.2-39.2178.4-173.6-173.938.100112.6G551 I553 Q559G551-Q555 WeakPolarHBondContact O-CB 3.09Å; G551-Q555 PolarHBondContact O-N 3.04Å; I553-Q555 VanDerWaalsContact C-N 3.33Å; I553-Q555 PolarHBondContact O-N 2.78Å; Q555-Q559 WeakPolarHBondContact O-CG 3.47Å
556S94.4Very high92.4Very high1 Ų161.3 Ų61.31%0.00733%0.327CS..Hα-helixtrans-70.6-42.3179.1-179.70000112.8S444 Q448 V552 I553 A554 Q559S444-S556 WeakPolarHBondContact CB-OG 3.49Å; S444-S556 WeakPolarHBondContact OG-CB 3.24Å; S444-S556 PolarHBondContact OG-OG 2.86Å; Q448-S556 PolarHBondContact NE2-OG 3.47Å; V552-S556 PolarHBondContact O-N 2.98Å; V552-S556 VanDerWaalsContact O-N 3.15Å; I553-S556 WeakPolarHBondContact O-CB 3.28Å; I553-S556 PolarHBondContact O-N 2.86Å; A554-S556 PolarHBondContact O-N 3.42Å; A554-S556 VanDerWaalsContact O-N 3.16Å; S556-Q559 WeakPolarHBondContact O-CB 3.4Å; S556-Q559 WeakPolarHBondContact O-CG 3.43Å; S556-Q559 PolarHBondContact O-N 3.15Å
557Y94.4Very high93.3Very high4 Ų460.1 Ų60.12%0.01632%0.318CS..Hα-helixtrans-70.6-33.2178.1-85.9-95.9000112.3S444 D447 Q448 I553 A554 Q559 S563 A564 F567 M698 L699S444-Y557 VanDerWaalsContact OG-CD2 3.22Å; S444-Y557 WeakPolarHBondContact OG-CD2 3.3Å; S444-Y557 WeakPolarHBondContact OG-CE2 3.31Å; D447-Y557 VanDerWaalsContact CB-OH 3.29Å; D447-Y557 WeakPolarHBondContact CB-OH 3.43Å; Q448-Y557 HydrophobicContact CG-CD1 4.16Å; Q448-Y557 HydrophobicContact CG-CE1 3.76Å; I553-Y557 HydrophobicContact CG2-CD2 3.79Å; I553-Y557 HydrophobicContact CG2-CE2 3.91Å; I553-Y557 WeakPolarHBondContact O-CD2 3.22Å; I553-Y557 PolarHBondContact O-N 2.64Å; A554-Y557 PolarHBondContact O-N 2.97Å; A554-Y557 VanDerWaalsContact O-N 3.13Å; Y557-Q559 PolarHBondContact O-N 3.25Å; Y557-Q559 VanDerWaalsContact O-N 3.16Å; Y557-S563 CarbonylContact O-C 3.45Å; Y557-S563 VanDerWaalsContact O-CB 3.29Å; Y557-S563 WeakPolarHBondContact O-CB 3.41Å; Y557-S563 PolarHBondContact O-OG 3.02Å; Y557-A564 PolarHBondContact O-N 2.99Å; Y557-A564 VanDerWaalsContact O-N 3.12Å; Y557-F567 HydrophobicContact CD1-CB 4.27Å; Y557-F567 HydrophobicContact CD2-CD2 4.27Å; Y557-F567 HydrophobicContact CG-CB 4.32Å; Y557-F567 HydrophobicContact CG-CD2 4.04Å; Y557-M698 HydrophobicContact CE2-CE 4.05Å; Y557-L699 HydrophobicContact CD1-CD1 3.98Å; Y557-L699 HydrophobicContact CE1-CD1 3.37Å; Y557-L699 HydrophobicContact CE1-CG 4.09Å
558H95.4Very high93.9Very high91 Ų9156.8 Ų56.842%0.42131%0.305SS..THydrogen-bonded Turntrans-75.74.7176.5-66119.2000114.6A554 S560 F567 D568A554-H558 PolarHBondContact O-N 3.24Å; A554-H558 PolarHBondContact O-ND1 2.69Å; H558-S560 VanDerWaalsContact C-N 3.27Å; H558-S560 PolarHBondContact O-N 2.9Å; H558-F567 AromaticContact CE1-CD1 3.75Å; H558-F567 AromaticContact CE1-CE1 3.93Å; H558-F567 AromaticContact NE2-CD1 3.96Å; H558-D568 IonicContact CD2-OD1 3.78Å; H558-D568 IonicContact CE1-OD1 3.77Å; H558-D568 IonicContact NE2-OD1 2.92Å; H558-D568 PolarHBondContact NE2-OD1 3.37Å; H558-D568 IonicContact NE2-OD2 3.4Å
559Q92.2Very high94.2Very high122 Ų12257.4 Ų57.457%0.5731%0.313SS*.THydrogen-bonded Turntrans-74.4-12.8173.5-64.2-175.9-8.800114.1Q555 S556 Y557Q555-Q559 WeakPolarHBondContact O-CG 3.47Å; S556-Q559 WeakPolarHBondContact O-CB 3.4Å; S556-Q559 WeakPolarHBondContact O-CG 3.43Å; S556-Q559 PolarHBondContact O-N 3.15Å; Y557-Q559 PolarHBondContact O-N 3.25Å; Y557-Q559 VanDerWaalsContact O-N 3.16Å
560S91.1Very high94.3Very high46 Ų4656.7 Ų56.732%0.32231%0.308SS..SBendtrans-144.7145.2173.585.10000111.2H558 K562 S563 A564H558-S560 VanDerWaalsContact C-N 3.27Å; H558-S560 PolarHBondContact O-N 2.9Å; S560-K562 PolarHBondContact O-N 3.27Å; S560-S563 PolarHBondContact O-N 3Å; S560-S563 PolarHBondContact O-OG 3.4Å; S560-S563 VanDerWaalsContact O-OG 3.05Å; S560-S563 PolarHBondContact OG-N 3.34Å; S560-S563 PolarHBondContact OG-OG 2.85Å; S560-A564 VanDerWaalsContact O-CB 3.32Å; S560-A564 WeakPolarHBondContact O-CB 3.36Å; S560-A564 PolarHBondContact O-N 3.33Å
561E91.8Very high94.5Very high179 Ų17954 Ų5484%0.83629%0.292SS*.Hα-helixtrans-56.7-38.1-178.6-67.3179.3176.200112.4S565E561-S565 PolarHBondContact O-N 3.03Å
562K90.8Very high94.6Very high173 Ų17354.8 Ų54.875%0.75230%0.295SS*.Hα-helixtrans-63.5-53.2179.6-176.4-175.1174.2-169.90111.6S560 A564 S565 E566S560-K562 PolarHBondContact O-N 3.27Å; K562-A564 VanDerWaalsContact C-N 3.33Å; K562-S565 PolarHBondContact O-N 2.79Å; K562-S565 PolarHBondContact O-OG 3.37Å; K562-E566 PolarHBondContact O-N 3.24Å
563S92.1Very high94.7Very high8 Ų857.7 Ų57.76%0.05631%0.308CS..Hα-helixtrans-67.4-35.1-179.748.10000111.9Y557 S560 S565 E566 F567Y557-S563 CarbonylContact O-C 3.45Å; Y557-S563 VanDerWaalsContact O-CB 3.29Å; Y557-S563 WeakPolarHBondContact O-CB 3.41Å; Y557-S563 PolarHBondContact O-OG 3.02Å; S560-S563 PolarHBondContact O-N 3Å; S560-S563 PolarHBondContact O-OG 3.4Å; S560-S563 VanDerWaalsContact O-OG 3.05Å; S560-S563 PolarHBondContact OG-N 3.34Å; S560-S563 PolarHBondContact OG-OG 2.85Å; S563-S565 PolarHBondContact O-N 2.93Å; S563-E566 PolarHBondContact O-N 3.1Å; S563-F567 PolarHBondContact O-N 2.84Å
564A94.3Very high94.8Very high13 Ų1357.9 Ų57.911%0.10731%0.309CS..Hα-helixtrans-57.2-48.5172.700000111.4Y557 S560 K562 E566 F567 D568Y557-A564 PolarHBondContact O-N 2.99Å; Y557-A564 VanDerWaalsContact O-N 3.12Å; S560-A564 VanDerWaalsContact O-CB 3.32Å; S560-A564 WeakPolarHBondContact O-CB 3.36Å; S560-A564 PolarHBondContact O-N 3.33Å; K562-A564 VanDerWaalsContact C-N 3.33Å; A564-E566 VanDerWaalsContact C-N 3.3Å; A564-E566 PolarHBondContact O-N 3.43Å; A564-F567 PolarHBondContact O-N 3.45Å; A564-D568 WeakPolarHBondContact O-CB 3.39Å; A564-D568 PolarHBondContact O-N 2.69Å
565S95.3Very high94.8Very high74 Ų7463 Ų6352%0.51733%0.329SS..Hα-helixtrans-61.2-34.8-177.569.40000114.2E561 K562 S563 A569E561-S565 PolarHBondContact O-N 3.03Å; K562-S565 PolarHBondContact O-N 2.79Å; K562-S565 PolarHBondContact O-OG 3.37Å; S563-S565 PolarHBondContact O-N 2.93Å; S565-A569 WeakPolarHBondContact O-CB 3.18Å; S565-A569 PolarHBondContact O-N 3.1Å; S565-A569 VanDerWaalsContact O-N 3.16Å
566E93.6Very high94.9Very high79 Ų7962.3 Ų62.337%0.36933%0.327SS..Hα-helixtrans-71.5-41.3177.3-177176.6-165.500111.7K562 S563 A564 L699 R703K562-E566 PolarHBondContact O-N 3.24Å; S563-E566 PolarHBondContact O-N 3.1Å; A564-E566 VanDerWaalsContact C-N 3.3Å; A564-E566 PolarHBondContact O-N 3.43Å; E566-L699 HydrophobicContact CG-CD1 3.86Å; E566-R703 IonicContact OE1-NH2 2.81Å
567F96Very high95Very high5 Ų562.6 Ų62.62%0.02233%0.328CS..Hα-helixtrans-64.7-51.3176.4-174.6-84.1000111I553 A554 Y557 H558 S563 A564 A569 I570 V571 D610 L611 L699I553-F567 HydrophobicContact CG2-CE2 4.11Å; A554-F567 HydrophobicContact CB-CE1 4.16Å; A554-F567 HydrophobicContact CB-CE2 4.42Å; A554-F567 HydrophobicContact CB-CZ 3.8Å; Y557-F567 HydrophobicContact CD1-CB 4.27Å; Y557-F567 HydrophobicContact CD2-CD2 4.27Å; Y557-F567 HydrophobicContact CG-CB 4.32Å; Y557-F567 HydrophobicContact CG-CD2 4.04Å; H558-F567 AromaticContact CE1-CD1 3.75Å; H558-F567 AromaticContact CE1-CE1 3.93Å; H558-F567 AromaticContact NE2-CD1 3.96Å; S563-F567 PolarHBondContact O-N 2.84Å; A564-F567 PolarHBondContact O-N 3.45Å; F567-A569 PolarHBondContact O-N 3.22Å; F567-I570 PolarHBondContact O-N 2.94Å; F567-V571 HydrophobicContact CD1-CG2 3.9Å; F567-V571 HydrophobicContact CE1-CG2 3.59Å; F567-V571 HydrophobicContact CZ-CG2 4.4Å; F567-V571 PolarHBondContact O-N 3.44Å; F567-V571 VanDerWaalsContact O-N 3.13Å; F567-D610 HydrophobicContact CE2-CB 4.35Å; F567-D610 HydrophobicContact CZ-CB 3.94Å; F567-D610 WeakPolarHBondContact CZ-O 3.46Å; F567-L611 HydrophobicContact CD1-CD2 4.22Å; F567-L611 HydrophobicContact CD2-CD2 3.62Å; F567-L611 HydrophobicContact CD2-CG 4.42Å; F567-L611 HydrophobicContact CE1-CD2 4.02Å; F567-L611 HydrophobicContact CE2-CD2 3.38Å; F567-L611 HydrophobicContact CE2-CG 3.78Å; F567-L611 HydrophobicContact CG-CD2 4.02Å; F567-L611 HydrophobicContact CZ-CD2 3.59Å; F567-L611 HydrophobicContact CZ-CG 4Å; F567-L699 HydrophobicContact CD2-CD2 4.24Å
568D96.9Very high95.1Very high76 Ų7665.6 Ų65.641%0.40634%0.344SS..Hα-helixtrans-63.2-29.1-178.4-63.8-18.9000112H558 A564 I570 V571 A572H558-D568 IonicContact CD2-OD1 3.78Å; H558-D568 IonicContact CE1-OD1 3.77Å; H558-D568 IonicContact NE2-OD1 2.92Å; H558-D568 PolarHBondContact NE2-OD1 3.37Å; H558-D568 IonicContact NE2-OD2 3.4Å; A564-D568 WeakPolarHBondContact O-CB 3.39Å; A564-D568 PolarHBondContact O-N 2.69Å; D568-I570 VanDerWaalsContact C-N 3.35Å; D568-I570 PolarHBondContact O-N 2.92Å; D568-V571 PolarHBondContact O-N 3.12Å; D568-A572 PolarHBondContact O-N 3.34Å
569A96.2Very high95.1Very high48 Ų4864.8 Ų64.840%0.39735%0.353SS..Hα-helixtrans-65.5-35.1174.300000113S565 F567 Q573S565-A569 WeakPolarHBondContact O-CB 3.18Å; S565-A569 PolarHBondContact O-N 3.1Å; S565-A569 VanDerWaalsContact O-N 3.16Å; F567-A569 PolarHBondContact O-N 3.22Å; A569-Q573 WeakPolarHBondContact O-CG 3.32Å; A569-Q573 PolarHBondContact O-N 3.37Å
570I96.3Very high95.3Very high0 Ų064.4 Ų64.40%035%0.354CS..Hα-helixtrans-76.5-38.8175.7-63.6170.7000110.1F567 D568 A572 Q573 T574 L611 L699 V702 R703F567-I570 PolarHBondContact O-N 2.94Å; D568-I570 VanDerWaalsContact C-N 3.35Å; D568-I570 PolarHBondContact O-N 2.92Å; I570-A572 VanDerWaalsContact C-N 3.28Å; I570-A572 PolarHBondContact O-N 3.26Å; I570-Q573 WeakPolarHBondContact O-CB 3.39Å; I570-Q573 PolarHBondContact O-N 2.87Å; I570-T574 PolarHBondContact O-N 3.32Å; I570-L611 HydrophobicContact CB-CD2 3.94Å; I570-L611 HydrophobicContact CG2-CB 4.35Å; I570-L611 HydrophobicContact CG2-CD1 4.31Å; I570-L611 HydrophobicContact CG2-CD2 3.89Å; I570-L611 HydrophobicContact CG2-CG 4.42Å; I570-L699 HydrophobicContact CD1-CB 3.74Å; I570-L699 HydrophobicContact CD1-CD1 4.35Å; I570-L699 HydrophobicContact CD1-CD2 4.16Å; I570-L699 HydrophobicContact CD1-CG 4.29Å; I570-L699 WeakPolarHBondContact CD1-O 3.18Å; I570-V702 HydrophobicContact CG2-CG1 3.98Å; I570-R703 HydrophobicContact CD1-CB 4.41Å
571V97.4Very high95.4Very high34 Ų3465.4 Ų65.421%0.20636%0.356CS..Hα-helixtrans-56.5-43.7172.71760000110.8F567 D568 Q573 T574 E575 L611F567-V571 HydrophobicContact CD1-CG2 3.9Å; F567-V571 HydrophobicContact CE1-CG2 3.59Å; F567-V571 HydrophobicContact CZ-CG2 4.4Å; F567-V571 PolarHBondContact O-N 3.44Å; F567-V571 VanDerWaalsContact O-N 3.13Å; D568-V571 PolarHBondContact O-N 3.12Å; V571-Q573 VanDerWaalsContact C-N 3.26Å; V571-Q573 PolarHBondContact O-N 2.85Å; V571-T574 PolarHBondContact O-N 2.96Å; V571-T574 PolarHBondContact O-OG1 3.17Å; V571-E575 HydrophobicContact CG1-CG 4.44Å; V571-E575 WeakPolarHBondContact O-CG 2.96Å; V571-E575 PolarHBondContact O-N 3.4Å; V571-L611 HydrophobicContact CG2-CD2 4.12Å
572A97.2Very high95.6Very high51 Ų5160.1 Ų60.142%0.42135%0.349SS..Hα-helixtrans-61.7-33.2175.900000112.9D568 I570 Q576D568-A572 PolarHBondContact O-N 3.34Å; I570-A572 VanDerWaalsContact C-N 3.28Å; I570-A572 PolarHBondContact O-N 3.26Å; A572-Q576 WeakPolarHBondContact O-CB 3.15Å; A572-Q576 PolarHBondContact O-N 3.17Å
573Q96.2Very high95.9Very high72 Ų7256 Ų5634%0.33633%0.329SS..Hα-helixtrans-71.2-38.2175.8-66.8172.416.200112.1A569 I570 V571 Q576 F577 L706A569-Q573 WeakPolarHBondContact O-CG 3.32Å; A569-Q573 PolarHBondContact O-N 3.37Å; I570-Q573 WeakPolarHBondContact O-CB 3.39Å; I570-Q573 PolarHBondContact O-N 2.87Å; V571-Q573 VanDerWaalsContact C-N 3.26Å; V571-Q573 PolarHBondContact O-N 2.85Å; Q573-Q576 PolarHBondContact O-N 2.86Å; Q573-F577 PolarHBondContact O-N 2.89Å; Q573-L706 HydrophobicContact CB-CD2 3.48Å; Q573-L706 VanDerWaalsContact CB-CD2 3.48Å
574T97Very high96.1Very high4 Ų461.2 Ų61.23%0.02535%0.348CS..Hα-helixtrans-71.9-33.3176.359.40000111.9I570 V571 F577 L578 P585 L611 F613 L706I570-T574 PolarHBondContact O-N 3.32Å; V571-T574 PolarHBondContact O-N 2.96Å; V571-T574 PolarHBondContact O-OG1 3.17Å; T574-F577 PolarHBondContact O-N 3.28Å; T574-L578 PolarHBondContact O-N 3.43Å; T574-P585 HydrophobicContact CG2-CG 4.11Å; T574-L611 WeakPolarHBondContact CB-O 3.46Å; T574-L611 VanDerWaalsContact CG2-O 3.27Å; T574-L611 WeakPolarHBondContact CG2-O 3.45Å; T574-L611 PolarHBondContact OG1-O 2.72Å; T574-F613 HydrophobicContact CG2-CD2 3.88Å; T574-F613 HydrophobicContact CG2-CE2 3.53Å; T574-F613 HydrophobicContact CG2-CZ 4.41Å; T574-L706 HydrophobicContact CG2-CD1 4.38Å; T574-L706 HydrophobicContact CG2-CD2 3.85Å
575E97.1Very high96.3Very high125 Ų12560.6 Ų60.658%0.58434%0.342SS*.Hα-helixtrans-63.8-40.7169.3-72.9-179.2159.800111.9V571 L578 A579V571-E575 HydrophobicContact CG1-CG 4.44Å; V571-E575 WeakPolarHBondContact O-CG 2.96Å; V571-E575 PolarHBondContact O-N 3.4Å; E575-L578 WeakPolarHBondContact O-CB 3.49Å; E575-L578 PolarHBondContact O-N 3.34Å; E575-A579 PolarHBondContact O-N 2.88Å
576Q96.3Very high96.4Very high104 Ų10460.4 Ų60.449%0.48633%0.33SS..Hα-helixtrans-65-44.7174.1-173.959.355.600111.4A572 Q573 L578 A579 D580A572-Q576 WeakPolarHBondContact O-CB 3.15Å; A572-Q576 PolarHBondContact O-N 3.17Å; Q573-Q576 PolarHBondContact O-N 2.86Å; Q576-L578 VanDerWaalsContact C-N 3.27Å; Q576-L578 PolarHBondContact O-N 3.25Å; Q576-A579 WeakPolarHBondContact O-CB 3.3Å; Q576-A579 PolarHBondContact O-N 3.24Å; Q576-D580 PolarHBondContact NE2-OD1 2.91Å; Q576-D580 PolarHBondContact NE2-OD2 3.23Å; Q576-D580 PolarHBondContact O-N 3.46Å
577F96.8Very high96.7Very high7 Ų756.8 Ų56.83%0.03131%0.314CS..Hα-helixtrans-56.1-43.3174.1-174.8-79000111.6Q573 T574 D580 N581 R583 P585 H637 L706 I709Q573-F577 PolarHBondContact O-N 2.89Å; T574-F577 PolarHBondContact O-N 3.28Å; F577-D580 PolarHBondContact O-N 3.5Å; F577-N581 HydrophobicContact CD1-CB 4.26Å; F577-N581 HydrophobicContact CE1-CB 3.93Å; F577-N581 HydrophobicContact CZ-CB 4.35Å; F577-N581 WeakPolarHBondContact O-CB 3.47Å; F577-N581 PolarHBondContact O-N 2.93Å; F577-N581 PolarHBondContact O-ND2 3.48Å; F577-R583 WeakPolarHBondContact CD1-O 3.38Å; F577-P585 HydrophobicContact CD1-CB 3.9Å; F577-P585 HydrophobicContact CD1-CG 4.18Å; F577-P585 HydrophobicContact CE1-CB 3.9Å; F577-P585 HydrophobicContact CG-CB 4.29Å; F577-P585 HydrophobicContact CG-CG 4.46Å; F577-P585 HydrophobicContact CZ-CB 4.28Å; F577-H637 AromaticContact CE1-NE2 3.9Å; F577-H637 AromaticContact CZ-CD2 3.9Å; F577-H637 AromaticContact CZ-NE2 3.79Å; F577-L706 HydrophobicContact CB-CD1 4.32Å; F577-L706 HydrophobicContact CD2-CD1 4.03Å; F577-L706 HydrophobicContact CG-CD1 4.3Å; F577-I709 HydrophobicContact CE2-CD1 4.08Å; F577-I709 HydrophobicContact CE2-CG1 4.02Å; F577-I709 HydrophobicContact CZ-CD1 4.25Å
578L96.7Very high96.8Very high67 Ų6756.5 Ų56.535%0.35131%0.313SS..Hα-helixtrans-61.2-42.1174.8170.362.7000112.2T574 E575 Q576 D580 G582 R583 R584T574-L578 PolarHBondContact O-N 3.43Å; E575-L578 WeakPolarHBondContact O-CB 3.49Å; E575-L578 PolarHBondContact O-N 3.34Å; Q576-L578 VanDerWaalsContact C-N 3.27Å; Q576-L578 PolarHBondContact O-N 3.25Å; L578-D580 VanDerWaalsContact C-N 3.34Å; L578-G582 VanDerWaalsContact O-CA 3.32Å; L578-G582 WeakPolarHBondContact O-CA 3.43Å; L578-G582 PolarHBondContact O-N 3.26Å; L578-R583 WeakPolarHBondContact CA-O 3.36Å; L578-R583 VanDerWaalsContact CD1-CA 3.5Å; L578-R584 HydrophobicContact CD1-CG 4.26Å; L578-R584 HydrophobicContact CD2-CG 4.24Å
579A96.5Very high96.8Very high74 Ų7453.3 Ų53.361%0.61230%0.295SS*.Hα-helixtrans-64.1-39.2177.100000112.3E575 Q576E575-A579 PolarHBondContact O-N 2.88Å; Q576-A579 WeakPolarHBondContact O-CB 3.3Å; Q576-A579 PolarHBondContact O-N 3.24Å
580D95Very high96.9Very high113 Ų11351 Ų5160%0.60428%0.276SS*.Hα-helixtrans-80.5-35.7-175.8-64.5-27.2000112.9Q576 F577 L578Q576-D580 PolarHBondContact NE2-OD1 2.91Å; Q576-D580 PolarHBondContact NE2-OD2 3.23Å; Q576-D580 PolarHBondContact O-N 3.46Å; F577-D580 PolarHBondContact O-N 3.5Å; L578-D580 VanDerWaalsContact C-N 3.34Å
581N93.7Very high96.9Very high68 Ų6851.4 Ų51.436%0.36428%0.278SS..Hα-helixtrans-105-8.1-173.7-64.3-86.5000113.9F577 R583F577-N581 HydrophobicContact CD1-CB 4.26Å; F577-N581 HydrophobicContact CE1-CB 3.93Å; F577-N581 HydrophobicContact CZ-CB 4.35Å; F577-N581 WeakPolarHBondContact O-CB 3.47Å; F577-N581 PolarHBondContact O-N 2.93Å; F577-N581 PolarHBondContact O-ND2 3.48Å; N581-R583 PolarHBondContact O-N 3.47Å
582G96Very high96.8Very high67 Ų6750.4 Ų50.469%0.69127%0.271SS*.SBendtrans725-177.700000114.8L578L578-G582 VanDerWaalsContact O-CA 3.32Å; L578-G582 WeakPolarHBondContact O-CA 3.43Å; L578-G582 PolarHBondContact O-N 3.26Å
583R96.8Very high96.8Very high86 Ų8648.2 Ų48.233%0.32525%0.253SS..SBendtrans-150.8157.7175.566.8-178.6-173.61774.2110.9F577 L578 N581 D635 H637F577-R583 WeakPolarHBondContact CD1-O 3.38Å; L578-R583 WeakPolarHBondContact CA-O 3.36Å; L578-R583 VanDerWaalsContact CD1-CA 3.5Å; N581-R583 PolarHBondContact O-N 3.47Å; R583-D635 IonicContact CZ-OD2 3.53Å; R583-D635 IonicContact NH1-OD2 3.76Å; R583-D635 PolarHBondContact NH1-OD2 3.01Å; R583-D635 IonicContact NH2-OD2 3.52Å; R583-H637 VanDerWaalsContact CZ-CE1 3.5Å; R583-H637 VanDerWaalsContact CZ-NE2 3.33Å; R583-H637 PolarHBondContact NE-CE1 3.02Å; R583-H637 PolarHBondContact NE-NE2 2.99Å; R583-H637 PolarHBondContact NH2-CE1 3.33Å; R583-H637 PolarHBondContact NH2-NE2 2.91Å
584R97.3Very high96.8Very high118 Ų11844.8 Ų44.845%0.44524%0.237SC..  trans-67154175.7-74.4173.8173.5-176.4-4.5110.9L578 R586 G612 D614 H637L578-R584 HydrophobicContact CD1-CG 4.26Å; L578-R584 HydrophobicContact CD2-CG 4.24Å; R584-R586 PolarHBondContact O-N 2.94Å; R584-G612 WeakPolarHBondContact CD-O 3.24Å; R584-D614 VanDerWaalsContact CD-OD1 3.27Å; R584-D614 WeakPolarHBondContact CD-OD1 3.49Å; R584-D614 IonicContact NH1-OD1 2.8Å; R584-H637 PolarHBondContact O-CE1 2.72Å
585P97.8Very high96.8Very high0 Ų044.9 Ų44.90%024%0.238CC..  trans-61.8134.1167.730.2-34.4000108.4T574 F577 F613 D614 L706 I709T574-P585 HydrophobicContact CG2-CG 4.11Å; F577-P585 HydrophobicContact CD1-CB 3.9Å; F577-P585 HydrophobicContact CD1-CG 4.18Å; F577-P585 HydrophobicContact CE1-CB 3.9Å; F577-P585 HydrophobicContact CG-CB 4.29Å; F577-P585 HydrophobicContact CG-CG 4.46Å; F577-P585 HydrophobicContact CZ-CB 4.28Å; P585-F613 HydrophobicContact CB-CD1 3.58Å; P585-F613 HydrophobicContact CB-CE1 3.49Å; P585-F613 VanDerWaalsContact CB-CE1 3.49Å; P585-F613 HydrophobicContact CB-CG 4.25Å; P585-F613 HydrophobicContact CB-CZ 4.07Å; P585-F613 HydrophobicContact CG-CD1 3.6Å; P585-F613 HydrophobicContact CG-CD2 3.96Å; P585-F613 HydrophobicContact CG-CE1 3.71Å; P585-F613 HydrophobicContact CG-CE2 4.02Å; P585-F613 HydrophobicContact CG-CG 3.75Å; P585-F613 HydrophobicContact CG-CZ 3.9Å; P585-F613 CarbonylContact O-C 3.44Å; P585-F613 VanDerWaalsContact O-CA 3.29Å; P585-F613 WeakPolarHBondContact O-CA 3.35Å; P585-F613 WeakPolarHBondContact O-CB 3.46Å; P585-F613 WeakPolarHBondContact O-CD1 3.34Å; P585-D614 PolarHBondContact O-N 2.78Å; P585-L706 HydrophobicContact CB-CD1 4.14Å; P585-L706 HydrophobicContact CG-CD1 4.11Å; P585-I709 HydrophobicContact CB-CD1 3.56Å
586R98.2Very high96.6Very high70 Ų7039.1 Ų39.126%0.26421%0.212SC..EExtended strand (participates in β ladder)trans-122.9124.2-171.2-169.6176.9-174162.210.1110.6R584 D614 D616 N634 V636 H637 V638R584-R586 PolarHBondContact O-N 2.94Å; R586-D614 VanDerWaalsContact CA-O 3.28Å; R586-D614 WeakPolarHBondContact CA-O 3.35Å; R586-D614 HydrophobicContact CB-CB 4.24Å; R586-D614 HydrophobicContact CG-CB 3.95Å; R586-D614 WeakPolarHBondContact CG-O 3.42Å; R586-D616 IonicContact CZ-OD1 3.69Å; R586-D616 IonicContact CZ-OD2 2.68Å; R586-D616 VanDerWaalsContact CZ-OD2 3.23Å; R586-D616 IonicContact NE-OD1 3.57Å; R586-D616 IonicContact NE-OD2 3.24Å; R586-D616 PolarHBondContact NE-OD2 2.61Å; R586-D616 IonicContact NH2-OD1 3.12Å; R586-D616 PolarHBondContact NH2-OD1 3.25Å; R586-D616 IonicContact NH2-OD2 2.78Å; R586-D616 PolarHBondContact NH2-OD2 2.92Å; R586-N634 WeakPolarHBondContact CD-O 3.34Å; R586-N634 VanDerWaalsContact CZ-O 3.26Å; R586-N634 PolarHBondContact NE-O 3.34Å; R586-N634 PolarHBondContact NH1-O 3.04Å; R586-V636 HydrophobicContact CG-CB 4.39Å; R586-V636 HydrophobicContact CG-CG1 4.01Å; R586-H637 PolarHBondContact N-ND1 2.78Å; R586-H637 PolarHBondContact O-N 3.08Å; R586-V638 PolarHBondContact O-N 3.22Å
587I98.3Very high96.6Very high3 Ų339 Ų392%0.01521%0.211CC..EExtended strand (participates in β ladder)trans-121.1135.5-177.7-179.2163.9000110.9I589 Y608 F613 D614 V615 D616 V638I587-I589 HydrophobicContact CD1-CG1 4.08Å; I587-I589 HydrophobicContact CG1-CG1 4.02Å; I587-Y608 HydrophobicContact CB-CD1 4.4Å; I587-Y608 HydrophobicContact CD1-CD1 4.01Å; I587-Y608 HydrophobicContact CD1-CE1 3.58Å; I587-Y608 HydrophobicContact CG2-CD1 3.66Å; I587-Y608 HydrophobicContact CG2-CE1 4.28Å; I587-Y608 HydrophobicContact CG2-CG 4.24Å; I587-F613 HydrophobicContact CG2-CB 4.45Å; I587-F613 HydrophobicContact CG2-CD1 4.16Å; I587-D614 PolarHBondContact N-O 2.91Å; I587-V615 HydrophobicContact CG2-CB 4.38Å; I587-V615 HydrophobicContact CG2-CG1 4.32Å; I587-V615 HydrophobicContact CG2-CG2 3.92Å; I587-D616 PolarHBondContact O-N 3.18Å; I587-V638 WeakPolarHBondContact CA-O 3.09Å; I587-V638 HydrophobicContact CB-CG1 3.78Å; I587-V638 HydrophobicContact CD1-CG1 4.08Å; I587-V638 HydrophobicContact CG1-CG1 3.84Å
588L98.3Very high96.5Very high0 Ų039.2 Ų39.20%021%0.213CC..EExtended strand (participates in β ladder)trans-98.6112.3163.2174.262000109.1D616 I627 L630 A631 V636 V638 V639 G640L588-D616 WeakPolarHBondContact CA-O 3.21Å; L588-D616 HydrophobicContact CD1-CB 3.8Å; L588-I627 HydrophobicContact CD2-CG2 4Å; L588-L630 HydrophobicContact CD1-CD2 3.77Å; L588-L630 HydrophobicContact CD1-CG 4.35Å; L588-L630 HydrophobicContact CD2-CB 4.26Å; L588-L630 HydrophobicContact CD2-CD2 4.1Å; L588-L630 HydrophobicContact CD2-CG 4.11Å; L588-A631 HydrophobicContact CD2-CB 3.96Å; L588-V636 HydrophobicContact CB-CG1 4.04Å; L588-V636 HydrophobicContact CB-CG2 4.19Å; L588-V638 PolarHBondContact N-O 3.5Å; L588-V639 HydrophobicContact CB-CG2 4.39Å; L588-V639 HydrophobicContact CD2-CG2 4.45Å; L588-V639 CarbonylContact O-C 3.54Å; L588-V639 WeakPolarHBondContact O-CA 3.42Å; L588-G640 PolarHBondContact O-N 2.91Å
589I97.9Very high96.4Very high8 Ų837.7 Ų37.74%0.04120%0.202CC..EExtended strand (participates in β ladder)trans-87113.9171.5-61.7173.8000108I587 A601 I604 A605 V615 D616 L617 S618I587-I589 HydrophobicContact CD1-CG1 4.08Å; I587-I589 HydrophobicContact CG1-CG1 4.02Å; I589-A601 HydrophobicContact CG2-CB 3.78Å; I589-I604 HydrophobicContact CD1-CG2 4Å; I589-A605 HydrophobicContact CD1-CB 3.61Å; I589-V615 HydrophobicContact CD1-CG1 4.05Å; I589-D616 PolarHBondContact N-O 2.87Å; I589-L617 HydrophobicContact CB-CD2 3.81Å; I589-L617 HydrophobicContact CD1-CD2 4.48Å; I589-L617 HydrophobicContact CG2-CD2 4.14Å; I589-S618 PolarHBondContact O-N 3.16Å; I589-S618 VanDerWaalsContact O-N 3.08Å
590A97.5Very high96.3Very high0 Ų035.9 Ų35.90%019%0.191CC..EExtended strand (participates in β ladder)trans-108.8133.6-168.100000112.6I627 V639 G640 S642A590-I627 HydrophobicContact CB-CD1 3.91Å; A590-I627 HydrophobicContact CB-CG1 4.18Å; A590-I627 HydrophobicContact CB-CG2 3.75Å; A590-V639 HydrophobicContact CB-CG1 3.88Å; A590-G640 PolarHBondContact N-O 2.74Å; A590-S642 PolarHBondContact O-N 3.45Å
591K96.7Very high96.4Very high8 Ų830.8 Ų30.84%0.03517%0.165CC..  trans-108.9121.1164-65.5-59.8-55.9-178.20108.7D595 H597 A601 S618 M620 S642K591-D595 WeakPolarHBondContact CE-O 3.43Å; K591-D595 IonicContact NZ-OD1 2.77Å; K591-D595 IonicContact NZ-OD2 2.55Å; K591-D595 PolarHBondContact NZ-OD2 3.4Å; K591-H597 WeakPolarHBondContact CE-O 3.43Å; K591-H597 PolarHBondContact NZ-O 2.62Å; K591-A601 HydrophobicContact CD-CB 4.24Å; K591-S618 PolarHBondContact N-OG 3.42Å; K591-M620 HydrophobicContact CB-SD 4.07Å; K591-M620 HydrophobicContact CG-CE 4.38Å; K591-M620 HydrophobicContact CG-SD 3.84Å; K591-S642 WeakPolarHBondContact CD-O 3.43Å; K591-S642 WeakPolarHBondContact CE-O 3.48Å; K591-S642 PolarHBondContact NZ-O 3.25Å
592M96.3Very high96.4Very high14 Ų1428.2 Ų28.27%0.06915%0.15CC..BIsolated β-bridgetrans-115157.6-178.6-67.6-178.8-69.200111.7S622 P624 I627 A641 L651 I652 L655M592-S622 VanDerWaalsContact CA-O 3.31Å; M592-S622 WeakPolarHBondContact CA-O 2.94Å; M592-P624 HydrophobicContact SD-CB 4.28Å; M592-P624 HydrophobicContact SD-CG 4.17Å; M592-I627 HydrophobicContact CG-CG1 3.7Å; M592-I627 HydrophobicContact SD-CG1 4.29Å; M592-A641 HydrophobicContact CE-CB 3.78Å; M592-L651 HydrophobicContact CB-CB 4.26Å; M592-L651 HydrophobicContact CB-CD1 4.1Å; M592-L651 HydrophobicContact CE-CB 4.36Å; M592-I652 HydrophobicContact CE-CG1 3.9Å; M592-L655 HydrophobicContact CE-CB 4.39Å; M592-L655 HydrophobicContact CE-CD2 3.92Å; M592-L655 HydrophobicContact SD-CB 3.9Å; M592-L655 HydrophobicContact SD-CD2 3.92Å; M592-L655 HydrophobicContact SD-CG 4.38Å
593G95.9Very high96.4Very high4 Ų425.5 Ų25.54%0.04112%0.12CC..THydrogen-bonded Turntrans69.9-146.1179.200000111.4F621 S622G593-F621 WeakPolarHBondContact O-CA 3.24Å; G593-S622 PolarHBondContact N-O 3.09Å; G593-S622 VanDerWaalsContact N-O 3.11Å
594Q96.6Very high96.4Very high1 Ų123.8 Ų23.81%0.00512%0.117CC..THydrogen-bonded Turntrans-98.29.6178.8-58.2-49.4-58.800113.6L108 R120 V121 D124 G596L108-Q594 HydrophobicContact CB-CB 3.55Å; L108-Q594 HydrophobicContact CD1-CB 4.36Å; R120-Q594 PolarHBondContact O-NE2 2.85Å; V121-Q594 HydrophobicContact CB-CG 4.31Å; V121-Q594 HydrophobicContact CG1-CG 3.6Å; D124-Q594 HydrophobicContact CB-CB 4.33Å; D124-Q594 HydrophobicContact CB-CG 4.31Å; D124-Q594 VanDerWaalsContact CG-N 3.34Å; D124-Q594 PolarHBondContact OD1-N 2.87Å; D124-Q594 WeakPolarHBondContact OD2-CG 3Å; D124-Q594 PolarHBondContact OD2-N 2.87Å; Q594-G596 PolarHBondContact O-N 3.44Å; Q594-G596 VanDerWaalsContact O-N 3.11Å
595D96Very high96.4Very high5 Ų518.1 Ų18.13%0.02710%0.096CC..  trans-64.2109.4-175.6-174.13.3000112.8K591 H597 M620 L644 A645K591-D595 WeakPolarHBondContact CE-O 3.43Å; K591-D595 IonicContact NZ-OD1 2.77Å; K591-D595 IonicContact NZ-OD2 2.55Å; K591-D595 PolarHBondContact NZ-OD2 3.4Å; D595-H597 WeakPolarHBondContact OD1-CB 3.47Å; D595-H597 IonicContact OD1-CE1 2.85Å; D595-H597 IonicContact OD1-CG 3.65Å; D595-H597 PolarHBondContact OD1-N 3.14Å; D595-H597 IonicContact OD1-ND1 2.93Å; D595-H597 PolarHBondContact OD1-ND1 3.21Å; D595-M620 VanDerWaalsContact O-CE 3.28Å; D595-M620 WeakPolarHBondContact O-CE 3.25Å; D595-L644 PolarHBondContact OD2-N 3.14Å; D595-A645 HydrophobicContact CB-CB 3.76Å
596G94.6Very high96.3Very high5 Ų518.1 Ų18.15%0.05210%0.096CC..  trans-82.9-10.4-179.800000115.3N197 Q594 D598N197-G596 PolarHBondContact ND2-O 2.87Å; Q594-G596 PolarHBondContact O-N 3.44Å; Q594-G596 VanDerWaalsContact O-N 3.11Å; G596-D598 PolarHBondContact O-N 3.38Å; G596-D598 VanDerWaalsContact O-N 3.16Å
597H94.8Very high96.2Very high100 Ų10014.8 Ų14.846%0.4638%0.083SC..  trans-73.9109.3-173.7-5793.5000111K591 D595 L644K591-H597 WeakPolarHBondContact CE-O 3.43Å; K591-H597 PolarHBondContact NZ-O 2.62Å; D595-H597 WeakPolarHBondContact OD1-CB 3.47Å; D595-H597 IonicContact OD1-CE1 2.85Å; D595-H597 IonicContact OD1-CG 3.65Å; D595-H597 PolarHBondContact OD1-N 3.14Å; D595-H597 IonicContact OD1-ND1 2.93Å; D595-H597 PolarHBondContact OD1-ND1 3.21Å; H597-L644 HydrophobicContact CB-CB 3.94Å; H597-L644 HydrophobicContact CB-CD1 4.16Å; H597-L644 HydrophobicContact CB-CD2 3.94Å; H597-L644 HydrophobicContact CB-CG 4.23Å
598D95Very high96.2Very high12 Ų1214.9 Ų14.96%0.0648%0.083CC..  trans-112.2-10-176.769.8-12.1000114.1N197 K432 G596 G600 A601 K602N197-D598 PolarHBondContact ND2-OD2 3.48Å; K432-D598 IonicContact NZ-OD2 3.49Å; K432-D598 PolarHBondContact NZ-OD2 3.27Å; G596-D598 PolarHBondContact O-N 3.38Å; G596-D598 VanDerWaalsContact O-N 3.16Å; D598-G600 PolarHBondContact O-N 3.5Å; D598-A601 PolarHBondContact O-N 3.4Å; D598-A601 VanDerWaalsContact O-N 3.17Å; D598-K602 HydrophobicContact CB-CG 4.11Å; D598-K602 WeakPolarHBondContact O-CB 3.38Å; D598-K602 WeakPolarHBondContact O-CG 3.32Å; D598-K602 PolarHBondContact O-N 3.12Å
599R95.5Very high96.1Very high35 Ų3517.1 Ų17.113%0.13210%0.099CC..Hα-helixtrans-49.2-57.6-178.8-179.5177.4-179174.9-3.7113.1E236 A237 W323 S439 K602 V603E236-R599 WeakPolarHBondContact O-CD 3.37Å; E236-R599 PolarHBondContact O-NH1 3.02Å; A237-R599 WeakPolarHBondContact O-CD 3.29Å; W323-R599 VanDerWaalsContact CD1-CZ 3.5Å; W323-R599 VanDerWaalsContact CE2-CZ 3.4Å; S439-R599 WeakPolarHBondContact OG-CG 3.17Å; S439-R599 PolarHBondContact OG-NE 3.48Å; R599-K602 PolarHBondContact O-N 2.9Å; R599-V603 WeakPolarHBondContact O-CG2 3.05Å; R599-V603 PolarHBondContact O-N 3.34Å
600G94.6Very high96Very high37 Ų3718 Ų1838%0.38110%0.104SC..Hα-helixtrans-60.8-46.5179.900000112D598 K602 V603 I604D598-G600 PolarHBondContact O-N 3.5Å; G600-K602 PolarHBondContact O-N 2.91Å; G600-V603 PolarHBondContact O-N 3.16Å; G600-I604 WeakPolarHBondContact O-CB 3.48Å; G600-I604 VanDerWaalsContact O-CG1 3.27Å; G600-I604 WeakPolarHBondContact O-CG1 3.13Å; G600-I604 PolarHBondContact O-N 3.41Å
601A95.9Very high96Very high6 Ų618 Ų185%0.0510%0.104CC..Hα-helixtrans-58.2-43.5177.300000112.6I589 K591 D598 A605I589-A601 HydrophobicContact CG2-CB 3.78Å; K591-A601 HydrophobicContact CD-CB 4.24Å; D598-A601 PolarHBondContact O-N 3.4Å; D598-A601 VanDerWaalsContact O-N 3.17Å; A601-A605 WeakPolarHBondContact O-CB 3.22Å; A601-A605 PolarHBondContact O-N 3.15Å
602K95.3Very high96Very high14 Ų1418.4 Ų18.46%0.06111%0.11CC..Hα-helixtrans-71.6-40.5-179.3-65.4-70.9-179-174.60112.7Q547 C548 D598 R599 G600 A605 S606 L617Q547-K602 VanDerWaalsContact O-CD 3.24Å; Q547-K602 WeakPolarHBondContact O-CD 3.32Å; Q547-K602 WeakPolarHBondContact O-CE 3.36Å; Q547-K602 PolarHBondContact O-NZ 2.76Å; C548-K602 HydrophobicContact CB-CD 4.13Å; D598-K602 HydrophobicContact CB-CG 4.11Å; D598-K602 WeakPolarHBondContact O-CB 3.38Å; D598-K602 WeakPolarHBondContact O-CG 3.32Å; D598-K602 PolarHBondContact O-N 3.12Å; R599-K602 PolarHBondContact O-N 2.9Å; G600-K602 PolarHBondContact O-N 2.91Å; K602-A605 PolarHBondContact O-N 2.87Å; K602-S606 WeakPolarHBondContact O-CB 3.33Å; K602-S606 PolarHBondContact O-N 2.94Å; K602-L617 HydrophobicContact CD-CD1 4.34Å
603V95.7Very high96.1Very high10 Ų1017.9 Ų17.96%0.06111%0.107CC..Hα-helixtrans-65.6-45.9176.8171.30000110.3Q443 R599 G600 S606 A607 M698Q443-V603 HydrophobicContact CB-CG1 3.74Å; Q443-V603 HydrophobicContact CG-CG1 3.74Å; R599-V603 WeakPolarHBondContact O-CG2 3.05Å; R599-V603 PolarHBondContact O-N 3.34Å; G600-V603 PolarHBondContact O-N 3.16Å; V603-S606 WeakPolarHBondContact O-CB 3.43Å; V603-S606 PolarHBondContact O-N 3.37Å; V603-A607 PolarHBondContact O-N 3.45Å; V603-M698 HydrophobicContact CG1-SD 4.02Å
604I96.3Very high96.2Very high49 Ų4920.8 Ų20.825%0.25112%0.122SC..Hα-helixtrans-62.4-43.3174-66.3-56.8000110.8I589 G600 S606 A607 Y608 M698I589-I604 HydrophobicContact CD1-CG2 4Å; G600-I604 WeakPolarHBondContact O-CB 3.48Å; G600-I604 VanDerWaalsContact O-CG1 3.27Å; G600-I604 WeakPolarHBondContact O-CG1 3.13Å; G600-I604 PolarHBondContact O-N 3.41Å; I604-S606 VanDerWaalsContact C-N 3.33Å; I604-S606 PolarHBondContact O-N 2.77Å; I604-A607 VanDerWaalsContact O-CB 3.32Å; I604-A607 WeakPolarHBondContact O-CB 3.28Å; I604-A607 PolarHBondContact O-N 3.33Å; I604-A607 VanDerWaalsContact O-N 3.07Å; I604-Y608 HydrophobicContact CG2-CD2 3.5Å; I604-Y608 HydrophobicContact CG2-CE2 3.4Å; I604-Y608 VanDerWaalsContact O-CD2 3.23Å; I604-Y608 WeakPolarHBondContact O-CD2 3.19Å; I604-Y608 PolarHBondContact O-N 2.89Å; I604-M698 HydrophobicContact CD1-CB 4.33Å; I604-M698 HydrophobicContact CD1-CG 3.85Å
605A96.7Very high96.2Very high0 Ų022.5 Ų22.50%013%0.132CC..Hα-helixtrans-57.3-45.1175.500000112.8C548 I589 A601 K602 A607 S609 V615 L617C548-A605 HydrophobicContact CB-CB 4.09Å; I589-A605 HydrophobicContact CD1-CB 3.61Å; A601-A605 WeakPolarHBondContact O-CB 3.22Å; A601-A605 PolarHBondContact O-N 3.15Å; K602-A605 PolarHBondContact O-N 2.87Å; A605-A607 VanDerWaalsContact C-N 3.29Å; A605-A607 PolarHBondContact O-N 2.99Å; A605-S609 WeakPolarHBondContact O-CB 3.46Å; A605-S609 PolarHBondContact O-N 2.89Å; A605-V615 HydrophobicContact CB-CG1 3.97Å; A605-L617 HydrophobicContact CB-CD1 4.35Å; A605-L617 HydrophobicContact CB-CD2 3.66Å; A605-L617 HydrophobicContact CB-CG 4.35Å
606S96.3Very high96.3Very high0 Ų023.8 Ų23.80%014%0.139CC..Hα-helixtrans-59.1-42.5175.2-168.90000111.1V549 K602 V603 I604 S609 D610V549-S606 WeakPolarHBondContact O-CB 3.5Å; V549-S606 PolarHBondContact O-OG 3.31Å; K602-S606 WeakPolarHBondContact O-CB 3.33Å; K602-S606 PolarHBondContact O-N 2.94Å; V603-S606 WeakPolarHBondContact O-CB 3.43Å; V603-S606 PolarHBondContact O-N 3.37Å; I604-S606 VanDerWaalsContact C-N 3.33Å; I604-S606 PolarHBondContact O-N 2.77Å; S606-S609 PolarHBondContact O-N 2.95Å; S606-D610 WeakPolarHBondContact O-CB 3.26Å; S606-D610 PolarHBondContact O-N 3.25Å
607A96.6Very high96.4Very high0 Ų025.2 Ų25.20%015%0.145CC..Hα-helixtrans-64.7-50.2-18000000112.8I553 V603 I604 A605 S609 D610 L611 M698I553-A607 VanDerWaalsContact CD1-CA 3.49Å; I553-A607 HydrophobicContact CD1-CB 3.67Å; I553-A607 VanDerWaalsContact CD1-N 3.33Å; V603-A607 PolarHBondContact O-N 3.45Å; I604-A607 VanDerWaalsContact O-CB 3.32Å; I604-A607 WeakPolarHBondContact O-CB 3.28Å; I604-A607 PolarHBondContact O-N 3.33Å; I604-A607 VanDerWaalsContact O-N 3.07Å; A605-A607 VanDerWaalsContact C-N 3.29Å; A605-A607 PolarHBondContact O-N 2.99Å; A607-S609 VanDerWaalsContact C-N 3.28Å; A607-S609 PolarHBondContact O-N 2.89Å; A607-D610 PolarHBondContact O-N 3.48Å; A607-L611 WeakPolarHBondContact O-CB 3.34Å; A607-L611 WeakPolarHBondContact O-CD1 3.47Å; A607-L611 WeakPolarHBondContact O-CG 3.32Å; A607-L611 PolarHBondContact O-N 2.89Å; A607-M698 HydrophobicContact CB-CE 3.94Å; A607-M698 HydrophobicContact CB-CG 3.37Å; A607-M698 HydrophobicContact CB-SD 3.19Å; A607-M698 WeakPolarHBondContact CB-SD 3.27Å
608Y97.4Very high96.3Very high5 Ų520.5 Ų20.52%0.0212%0.124CC..Hα-helixtrans-60.5-42.1178.8-86.2-108.5000110.4I587 I604 L611 G612 F613 V702 V705I587-Y608 HydrophobicContact CB-CD1 4.4Å; I587-Y608 HydrophobicContact CD1-CD1 4.01Å; I587-Y608 HydrophobicContact CD1-CE1 3.58Å; I587-Y608 HydrophobicContact CG2-CD1 3.66Å; I587-Y608 HydrophobicContact CG2-CE1 4.28Å; I587-Y608 HydrophobicContact CG2-CG 4.24Å; I604-Y608 HydrophobicContact CG2-CD2 3.5Å; I604-Y608 HydrophobicContact CG2-CE2 3.4Å; I604-Y608 VanDerWaalsContact O-CD2 3.23Å; I604-Y608 WeakPolarHBondContact O-CD2 3.19Å; I604-Y608 PolarHBondContact O-N 2.89Å; Y608-L611 PolarHBondContact O-N 2.92Å; Y608-G612 PolarHBondContact O-N 3.13Å; Y608-F613 HydrophobicContact CD1-CB 4.17Å; Y608-F613 AromaticContact CD1-CD1 3.5Å; Y608-F613 HydrophobicContact CD1-CD1 3.5Å; Y608-F613 AromaticContact CD1-CD2 3.81Å; Y608-F613 HydrophobicContact CD1-CD2 3.81Å; Y608-F613 AromaticContact CD1-CE1 3.68Å; Y608-F613 HydrophobicContact CD1-CE1 3.68Å; Y608-F613 HydrophobicContact CD1-CE2 4.01Å; Y608-F613 AromaticContact CD1-CG 3.56Å; Y608-F613 HydrophobicContact CD1-CG 3.56Å; Y608-F613 AromaticContact CD1-CZ 3.94Å; Y608-F613 HydrophobicContact CD1-CZ 3.94Å; Y608-F613 AromaticContact CE1-CD1 3.99Å; Y608-F613 HydrophobicContact CE1-CD1 3.99Å; Y608-F613 AromaticContact CE1-CE1 3.69Å; Y608-F613 HydrophobicContact CE1-CE1 3.69Å; Y608-F613 HydrophobicContact CE1-CE2 4.31Å; Y608-F613 HydrophobicContact CE1-CG 4.4Å; Y608-F613 AromaticContact CE1-CZ 3.87Å; Y608-F613 HydrophobicContact CE1-CZ 3.87Å; Y608-F613 HydrophobicContact CG-CD2 4.46Å; Y608-F613 HydrophobicContact CG-CG 4.36Å; Y608-F613 WeakPolarHBondContact O-CB 3.43Å; Y608-F613 PolarHBondContact O-N 2.96Å; Y608-V702 HydrophobicContact CD2-CG2 3.6Å; Y608-V702 HydrophobicContact CE1-CG1 4.46Å; Y608-V702 HydrophobicContact CE2-CB 4.27Å; Y608-V702 HydrophobicContact CE2-CG2 3.36Å; Y608-V702 HydrophobicContact CG-CG2 4.29Å; Y608-V705 HydrophobicContact CE1-CB 4.46Å; Y608-V705 HydrophobicContact CE1-CG1 4.15Å; Y608-V705 VanDerWaalsContact OH-CB 3.31Å; Y608-V705 WeakPolarHBondContact OH-CB 3.27Å; Y608-V705 WeakPolarHBondContact OH-CG2 3.38Å
609S96.4Very high96.2Very high46 Ų4623.2 Ų23.232%0.32214%0.142SC..Hα-helixtrans-62.4-46.2176.3-174.20000111.8A605 S606 A607 L611 G612A605-S609 WeakPolarHBondContact O-CB 3.46Å; A605-S609 PolarHBondContact O-N 2.89Å; S606-S609 PolarHBondContact O-N 2.95Å; A607-S609 VanDerWaalsContact C-N 3.28Å; A607-S609 PolarHBondContact O-N 2.89Å; S609-L611 PolarHBondContact O-N 3.27Å; S609-G612 PolarHBondContact O-N 2.92Å
610D97Very high96.1Very high27 Ų2722.3 Ų22.314%0.14414%0.14CC..Hα-helixtrans-65-27.6177.9-77.89.8000112.4G551 V552 I553 A554 F567 S606 A607G551-D610 WeakPolarHBondContact CA-OD1 3.46Å; G551-D610 WeakPolarHBondContact CA-OD2 3.39Å; G551-D610 PolarHBondContact N-OD1 2.85Å; G551-D610 PolarHBondContact N-OD2 3.4Å; V552-D610 PolarHBondContact N-OD2 3.03Å; I553-D610 WeakPolarHBondContact CB-OD2 3.44Å; I553-D610 PolarHBondContact N-OD2 3.5Å; I553-D610 VanDerWaalsContact N-OD2 3.11Å; A554-D610 HydrophobicContact CB-CB 4.22Å; A554-D610 PolarHBondContact N-OD2 3.22Å; F567-D610 HydrophobicContact CE2-CB 4.35Å; F567-D610 HydrophobicContact CZ-CB 3.94Å; F567-D610 WeakPolarHBondContact CZ-O 3.46Å; S606-D610 WeakPolarHBondContact O-CB 3.26Å; S606-D610 PolarHBondContact O-N 3.25Å; A607-D610 PolarHBondContact O-N 3.48Å
611L97.2Very high96.1Very high0 Ų021 Ų210%012%0.123CC..THydrogen-bonded Turntrans-91.23.6-179.7-69.3164.2000114.2F567 I570 V571 T574 A607 Y608 S609 L699 V702F567-L611 HydrophobicContact CD1-CD2 4.22Å; F567-L611 HydrophobicContact CD2-CD2 3.62Å; F567-L611 HydrophobicContact CD2-CG 4.42Å; F567-L611 HydrophobicContact CE1-CD2 4.02Å; F567-L611 HydrophobicContact CE2-CD2 3.38Å; F567-L611 HydrophobicContact CE2-CG 3.78Å; F567-L611 HydrophobicContact CG-CD2 4.02Å; F567-L611 HydrophobicContact CZ-CD2 3.59Å; F567-L611 HydrophobicContact CZ-CG 4Å; I570-L611 HydrophobicContact CB-CD2 3.94Å; I570-L611 HydrophobicContact CG2-CB 4.35Å; I570-L611 HydrophobicContact CG2-CD1 4.31Å; I570-L611 HydrophobicContact CG2-CD2 3.89Å; I570-L611 HydrophobicContact CG2-CG 4.42Å; V571-L611 HydrophobicContact CG2-CD2 4.12Å; T574-L611 WeakPolarHBondContact CB-O 3.46Å; T574-L611 VanDerWaalsContact CG2-O 3.27Å; T574-L611 WeakPolarHBondContact CG2-O 3.45Å; T574-L611 PolarHBondContact OG1-O 2.72Å; A607-L611 WeakPolarHBondContact O-CB 3.34Å; A607-L611 WeakPolarHBondContact O-CD1 3.47Å; A607-L611 WeakPolarHBondContact O-CG 3.32Å; A607-L611 PolarHBondContact O-N 2.89Å; Y608-L611 PolarHBondContact O-N 2.92Å; S609-L611 PolarHBondContact O-N 3.27Å; L611-L699 HydrophobicContact CD1-CD2 3.6Å; L611-L699 HydrophobicContact CD2-CD2 4.18Å; L611-L699 HydrophobicContact CG-CD2 4.42Å; L611-V702 HydrophobicContact CB-CG1 4.45Å; L611-V702 HydrophobicContact CD1-CB 3.95Å; L611-V702 HydrophobicContact CD1-CG1 3.7Å; L611-V702 HydrophobicContact CD1-CG2 3.67Å
612G96.6Very high96Very high16 Ų1621.1 Ų21.117%0.16512%0.124CC..THydrogen-bonded Turntrans96.613.9171.700000116.2R584 Y608 S609R584-G612 WeakPolarHBondContact CD-O 3.24Å; Y608-G612 PolarHBondContact O-N 3.13Å; S609-G612 PolarHBondContact O-N 2.92Å
613F97.9Very high96.1Very high4 Ų421.5 Ų21.52%0.01813%0.128CC..  trans-79.9152.6169.2-74.7-114.5000111.6T574 P585 I587 Y608 V615 V702 L706 I709T574-F613 HydrophobicContact CG2-CD2 3.88Å; T574-F613 HydrophobicContact CG2-CE2 3.53Å; T574-F613 HydrophobicContact CG2-CZ 4.41Å; P585-F613 HydrophobicContact CB-CD1 3.58Å; P585-F613 HydrophobicContact CB-CE1 3.49Å; P585-F613 VanDerWaalsContact CB-CE1 3.49Å; P585-F613 HydrophobicContact CB-CG 4.25Å; P585-F613 HydrophobicContact CB-CZ 4.07Å; P585-F613 HydrophobicContact CG-CD1 3.6Å; P585-F613 HydrophobicContact CG-CD2 3.96Å; P585-F613 HydrophobicContact CG-CE1 3.71Å; P585-F613 HydrophobicContact CG-CE2 4.02Å; P585-F613 HydrophobicContact CG-CG 3.75Å; P585-F613 HydrophobicContact CG-CZ 3.9Å; P585-F613 CarbonylContact O-C 3.44Å; P585-F613 VanDerWaalsContact O-CA 3.29Å; P585-F613 WeakPolarHBondContact O-CA 3.35Å; P585-F613 WeakPolarHBondContact O-CB 3.46Å; P585-F613 WeakPolarHBondContact O-CD1 3.34Å; I587-F613 HydrophobicContact CG2-CB 4.45Å; I587-F613 HydrophobicContact CG2-CD1 4.16Å; Y608-F613 HydrophobicContact CD1-CB 4.17Å; Y608-F613 AromaticContact CD1-CD1 3.5Å; Y608-F613 HydrophobicContact CD1-CD1 3.5Å; Y608-F613 AromaticContact CD1-CD2 3.81Å; Y608-F613 HydrophobicContact CD1-CD2 3.81Å; Y608-F613 AromaticContact CD1-CE1 3.68Å; Y608-F613 HydrophobicContact CD1-CE1 3.68Å; Y608-F613 HydrophobicContact CD1-CE2 4.01Å; Y608-F613 AromaticContact CD1-CG 3.56Å; Y608-F613 HydrophobicContact CD1-CG 3.56Å; Y608-F613 AromaticContact CD1-CZ 3.94Å; Y608-F613 HydrophobicContact CD1-CZ 3.94Å; Y608-F613 AromaticContact CE1-CD1 3.99Å; Y608-F613 HydrophobicContact CE1-CD1 3.99Å; Y608-F613 AromaticContact CE1-CE1 3.69Å; Y608-F613 HydrophobicContact CE1-CE1 3.69Å; Y608-F613 HydrophobicContact CE1-CE2 4.31Å; Y608-F613 HydrophobicContact CE1-CG 4.4Å; Y608-F613 AromaticContact CE1-CZ 3.87Å; Y608-F613 HydrophobicContact CE1-CZ 3.87Å; Y608-F613 HydrophobicContact CG-CD2 4.46Å; Y608-F613 HydrophobicContact CG-CG 4.36Å; Y608-F613 WeakPolarHBondContact O-CB 3.43Å; Y608-F613 PolarHBondContact O-N 2.96Å; F613-V615 HydrophobicContact CB-CG2 4.03Å; F613-V702 HydrophobicContact CD2-CG1 4.41Å; F613-V702 HydrophobicContact CE2-CG1 3.59Å; F613-V702 HydrophobicContact CZ-CG1 4.11Å; F613-L706 HydrophobicContact CZ-CB 4.17Å; F613-L706 HydrophobicContact CZ-CD1 4.04Å; F613-I709 HydrophobicContact CE1-CD1 4.29Å
614D97.8Very high96.2Very high65 Ų6521.2 Ų21.235%0.34813%0.126SC..EExtended strand (participates in β ladder)trans-83.9117.7159-69.5-20.5000108.2R584 P585 R586 I587R584-D614 VanDerWaalsContact CD-OD1 3.27Å; R584-D614 WeakPolarHBondContact CD-OD1 3.49Å; R584-D614 IonicContact NH1-OD1 2.8Å; P585-D614 PolarHBondContact O-N 2.78Å; R586-D614 VanDerWaalsContact CA-O 3.28Å; R586-D614 WeakPolarHBondContact CA-O 3.35Å; R586-D614 HydrophobicContact CB-CB 4.24Å; R586-D614 HydrophobicContact CG-CB 3.95Å; R586-D614 WeakPolarHBondContact CG-O 3.42Å; I587-D614 PolarHBondContact N-O 2.91Å
615V97.6Very high96.2Very high37 Ų3723.3 Ų23.322%0.22413%0.134CC..EExtended strand (participates in β ladder)trans-113119.8-172-177.30000110.4I587 I589 A605 F613I587-V615 HydrophobicContact CG2-CB 4.38Å; I587-V615 HydrophobicContact CG2-CG1 4.32Å; I587-V615 HydrophobicContact CG2-CG2 3.92Å; I589-V615 HydrophobicContact CD1-CG1 4.05Å; A605-V615 HydrophobicContact CB-CG1 3.97Å; F613-V615 HydrophobicContact CB-CG2 4.03Å
616D97Very high96.2Very high32 Ų3226.2 Ų26.217%0.17115%0.148CC..EExtended strand (participates in β ladder)trans-101.1140.7167.8-59.9-51.6000109.7R586 I587 L588 I589 N634R586-D616 IonicContact CZ-OD1 3.69Å; R586-D616 IonicContact CZ-OD2 2.68Å; R586-D616 VanDerWaalsContact CZ-OD2 3.23Å; R586-D616 IonicContact NE-OD1 3.57Å; R586-D616 IonicContact NE-OD2 3.24Å; R586-D616 PolarHBondContact NE-OD2 2.61Å; R586-D616 IonicContact NH2-OD1 3.12Å; R586-D616 PolarHBondContact NH2-OD1 3.25Å; R586-D616 IonicContact NH2-OD2 2.78Å; R586-D616 PolarHBondContact NH2-OD2 2.92Å; I587-D616 PolarHBondContact O-N 3.18Å; L588-D616 WeakPolarHBondContact CA-O 3.21Å; L588-D616 HydrophobicContact CD1-CB 3.8Å; I589-D616 PolarHBondContact N-O 2.87Å; D616-N634 VanDerWaalsContact CG-ND2 3.26Å; D616-N634 PolarHBondContact OD2-ND2 3.46Å
617L96.2Very high96.3Very high34 Ų3426.2 Ų26.218%0.17815%0.148CC..EExtended strand (participates in β ladder)trans-112.9129.4172.1-67.9167.6000109.1C548 I589 K602 A605C548-L617 HydrophobicContact CB-CD1 4.06Å; I589-L617 HydrophobicContact CB-CD2 3.81Å; I589-L617 HydrophobicContact CD1-CD2 4.48Å; I589-L617 HydrophobicContact CG2-CD2 4.14Å; K602-L617 HydrophobicContact CD-CD1 4.34Å; A605-L617 HydrophobicContact CB-CD1 4.35Å; A605-L617 HydrophobicContact CB-CD2 3.66Å; A605-L617 HydrophobicContact CB-CG 4.35Å
618S94.5Very high96.3Very high2 Ų226.2 Ų26.21%0.01415%0.148CC..PPolyproline II helixtrans-65.3152174.2760000111.1S546 I589 K591S546-S618 WeakPolarHBondContact CB-O 3.48Å; S546-S618 PolarHBondContact OG-O 2.92Å; I589-S618 PolarHBondContact O-N 3.16Å; I589-S618 VanDerWaalsContact O-N 3.08Å; K591-S618 PolarHBondContact N-OG 3.42Å
619P92.5Very high96.4Very high69 Ų6931.6 Ų31.645%0.44817%0.168SC..PPolyproline II helixtrans-54.2144.9158.2-22.134000109.9S622P619-S622 PolarHBondContact O-OG 2.81Å
620M92.3Very high96.4Very high16 Ų1631.2 Ų31.28%0.07916%0.163CC..THydrogen-bonded Turntrans-60.8148.8170.2-64.7-61.9-70.100109.7N197 K591 D595N197-M620 HydrophobicContact CB-CE 4.12Å; K591-M620 HydrophobicContact CB-SD 4.07Å; K591-M620 HydrophobicContact CG-CE 4.38Å; K591-M620 HydrophobicContact CG-SD 3.84Å; D595-M620 VanDerWaalsContact O-CE 3.28Å; D595-M620 WeakPolarHBondContact O-CE 3.25Å
621F94.5Very high96.5Very high9 Ų930 Ų304%0.03916%0.156CC..THydrogen-bonded Turntrans68.728.7174.4-30.3-64.1000116.5R112 R120 N197 Y199 L543 G593R112-F621 VanDerWaalsContact CZ-CG 3.48Å; R112-F621 VanDerWaalsContact NH1-CD2 3.31Å; R120-F621 PolarHBondContact NH2-O 2.85Å; N197-F621 HydrophobicContact CB-CZ 4.26Å; N197-F621 WeakPolarHBondContact O-CE1 3.43Å; N197-F621 WeakPolarHBondContact O-CZ 3.21Å; Y199-F621 HydrophobicContact CE2-CE2 4.08Å; L543-F621 HydrophobicContact CD2-CD2 4.35Å; G593-F621 WeakPolarHBondContact O-CA 3.24Å
622S94.9Very high96.5Very high8 Ų831.5 Ų31.56%0.05617%0.165CC..BIsolated β-bridgetrans-75.7146.4178-60.60000111.4M592 G593 P619 E626 I627M592-S622 VanDerWaalsContact CA-O 3.31Å; M592-S622 WeakPolarHBondContact CA-O 2.94Å; G593-S622 PolarHBondContact N-O 3.09Å; G593-S622 VanDerWaalsContact N-O 3.11Å; P619-S622 PolarHBondContact O-OG 2.81Å; S622-E626 VanDerWaalsContact CA-OE2 3.29Å; S622-E626 WeakPolarHBondContact CA-OE2 3.44Å; S622-I627 VanDerWaalsContact CB-CD1 3.42Å
623T96.8Very high96.5Very high23 Ų2337 Ų3714%0.14119%0.186CC..  trans-79.7161.1168.475.20000111R120 E625 E626 I627R120-T623 VanDerWaalsContact NH1-CG2 3.25Å; T623-E625 PolarHBondContact O-N 3.43Å; T623-E625 PolarHBondContact OG1-N 3.03Å; T623-E625 PolarHBondContact OG1-OE2 2.99Å; T623-E625 VanDerWaalsContact OG1-OE2 3.13Å; T623-E626 PolarHBondContact N-OE2 2.98Å; T623-E626 PolarHBondContact O-N 3.34Å; T623-E626 VanDerWaalsContact O-N 3.1Å; T623-E626 WeakPolarHBondContact OG1-CG 3.3Å; T623-E626 PolarHBondContact OG1-N 3.28Å; T623-I627 WeakPolarHBondContact O-CG1 3.4Å; T623-I627 PolarHBondContact O-N 2.8Å
624P97.1Very high96.5Very high4 Ų438.7 Ų38.73%0.02620%0.196CC..Hα-helixtrans-52.9-38.6172.3-28.237.5000113.7M592 I627 A628 L651 E654 L655M592-P624 HydrophobicContact SD-CB 4.28Å; M592-P624 HydrophobicContact SD-CG 4.17Å; P624-I627 PolarHBondContact O-N 2.89Å; P624-A628 WeakPolarHBondContact O-CB 3.42Å; P624-A628 PolarHBondContact O-N 2.92Å; P624-L651 HydrophobicContact CG-CB 4.3Å; P624-L651 HydrophobicContact CG-CD2 3.97Å; P624-L651 WeakPolarHBondContact CG-O 3.42Å; P624-E654 HydrophobicContact CB-CB 3.79Å; P624-E654 HydrophobicContact CG-CB 3.79Å; P624-L655 HydrophobicContact CB-CB 4.11Å
625E96.9Very high96.4Very high92 Ų9238.4 Ų38.443%0.4319%0.194SC..Hα-helixtrans-67.1-39176-63.877.3-17000113.2T623 A628 R629 A658T623-E625 PolarHBondContact O-N 3.43Å; T623-E625 PolarHBondContact OG1-N 3.03Å; T623-E625 PolarHBondContact OG1-OE2 2.99Å; T623-E625 VanDerWaalsContact OG1-OE2 3.13Å; E625-A628 PolarHBondContact O-N 3.4Å; E625-R629 WeakPolarHBondContact O-CB 3.43Å; E625-R629 PolarHBondContact O-N 3.09Å; E625-A658 HydrophobicContact CG-CB 4.5Å
626E96.8Very high96.5Very high61 Ų6136.7 Ų36.729%0.28518%0.184SC..Hα-helixtrans-66-39.9176.7-72.2162.9178.700110.9R120 S622 T623 L630R120-E626 IonicContact CZ-OE1 2.87Å; R120-E626 IonicContact CZ-OE2 3.42Å; R120-E626 IonicContact NH1-OE1 3.3Å; R120-E626 PolarHBondContact NH1-OE1 3.25Å; R120-E626 IonicContact NH1-OE2 3.39Å; R120-E626 IonicContact NH2-OE1 3.98Å; R120-E626 PolarHBondContact NH2-OE1 2.87Å; R120-E626 IonicContact NH2-OE2 2.85Å; R120-E626 PolarHBondContact NH2-OE2 2.86Å; S622-E626 VanDerWaalsContact CA-OE2 3.29Å; S622-E626 WeakPolarHBondContact CA-OE2 3.44Å; T623-E626 PolarHBondContact N-OE2 2.98Å; T623-E626 PolarHBondContact O-N 3.34Å; T623-E626 VanDerWaalsContact O-N 3.1Å; T623-E626 WeakPolarHBondContact OG1-CG 3.3Å; T623-E626 PolarHBondContact OG1-N 3.28Å; E626-L630 WeakPolarHBondContact O-CB 3.48Å; E626-L630 PolarHBondContact O-N 3.2Å
627I97.7Very high96.5Very high0 Ų035.4 Ų35.40%018%0.177CC..Hα-helixtrans-64.9-47.3173.5-64.2-55.5000111.1L588 A590 M592 S622 T623 P624 R629 L630 A631 V639 L655L588-I627 HydrophobicContact CD2-CG2 4Å; A590-I627 HydrophobicContact CB-CD1 3.91Å; A590-I627 HydrophobicContact CB-CG1 4.18Å; A590-I627 HydrophobicContact CB-CG2 3.75Å; M592-I627 HydrophobicContact CG-CG1 3.7Å; M592-I627 HydrophobicContact SD-CG1 4.29Å; S622-I627 VanDerWaalsContact CB-CD1 3.42Å; T623-I627 WeakPolarHBondContact O-CG1 3.4Å; T623-I627 PolarHBondContact O-N 2.8Å; P624-I627 PolarHBondContact O-N 2.89Å; I627-R629 VanDerWaalsContact C-N 3.32Å; I627-R629 PolarHBondContact O-N 2.9Å; I627-L630 PolarHBondContact O-N 3.08Å; I627-A631 WeakPolarHBondContact O-CB 3.31Å; I627-A631 PolarHBondContact O-N 3.33Å; I627-V639 HydrophobicContact CG2-CG1 3.99Å; I627-L655 HydrophobicContact CB-CD1 4Å; I627-L655 HydrophobicContact CG2-CD1 3.59Å; I627-L655 HydrophobicContact CG2-CD2 4.23Å
628A98.3Very high96.6Very high0 Ų033.8 Ų33.80%017%0.168CC..Hα-helixtrans-58.9-44.7178.400000111.4P624 E625 L630 A631 V632 L655 A658 L659P624-A628 WeakPolarHBondContact O-CB 3.42Å; P624-A628 PolarHBondContact O-N 2.92Å; E625-A628 PolarHBondContact O-N 3.4Å; A628-L630 PolarHBondContact O-N 3.29Å; A628-A631 PolarHBondContact O-N 3.17Å; A628-V632 WeakPolarHBondContact O-CG2 3.38Å; A628-V632 PolarHBondContact O-N 3.2Å; A628-V632 VanDerWaalsContact O-N 3.07Å; A628-L655 HydrophobicContact CB-CD1 4.14Å; A628-A658 HydrophobicContact CB-CB 3.52Å; A628-L659 HydrophobicContact CB-CD2 4.04Å; A628-L659 HydrophobicContact CB-CG 4.14Å
629R97.7Very high96.8Very high119 Ų11933.7 Ų33.745%0.44917%0.168SC..Hα-helixtrans-58.9-48.1174.9-178.4-178.162.6178.9-2.7111.6E625 I627 A631 V632 E633 W662E625-R629 WeakPolarHBondContact O-CB 3.43Å; E625-R629 PolarHBondContact O-N 3.09Å; I627-R629 VanDerWaalsContact C-N 3.32Å; I627-R629 PolarHBondContact O-N 2.9Å; R629-A631 PolarHBondContact O-N 2.9Å; R629-V632 PolarHBondContact O-N 2.91Å; R629-E633 WeakPolarHBondContact CD-OE1 3.44Å; R629-E633 HydrophobicContact CG-CG 4.26Å; R629-E633 VanDerWaalsContact CG-OE1 3.3Å; R629-E633 WeakPolarHBondContact CG-OE1 3.27Å; R629-E633 WeakPolarHBondContact O-CB 3.44Å; R629-E633 WeakPolarHBondContact O-CG 3.36Å; R629-E633 PolarHBondContact O-N 3.38Å; R629-W662 HydrophobicContact CB-CZ2 4.07Å; R629-W662 HydrophobicContact CG-CH2 4.34Å; R629-W662 HydrophobicContact CG-CZ2 4.05Å
630L96.9Very high97.1Very high38 Ų3831 Ų3120%0.19915%0.152CC..Hα-helixtrans-62.4-42180-177.862.3000112.1L588 E626 I627 A628 V632 E633 N634L588-L630 HydrophobicContact CD1-CD2 3.77Å; L588-L630 HydrophobicContact CD1-CG 4.35Å; L588-L630 HydrophobicContact CD2-CB 4.26Å; L588-L630 HydrophobicContact CD2-CD2 4.1Å; L588-L630 HydrophobicContact CD2-CG 4.11Å; E626-L630 WeakPolarHBondContact O-CB 3.48Å; E626-L630 PolarHBondContact O-N 3.2Å; I627-L630 PolarHBondContact O-N 3.08Å; A628-L630 PolarHBondContact O-N 3.29Å; L630-V632 VanDerWaalsContact C-N 3.31Å; L630-V632 PolarHBondContact O-N 2.95Å; L630-E633 PolarHBondContact O-N 3.14Å; L630-N634 VanDerWaalsContact O-CB 3.32Å; L630-N634 WeakPolarHBondContact O-CB 3.33Å; L630-N634 PolarHBondContact O-N 3.45Å
631A98.4Very high97.4Very high0 Ų030.2 Ų30.20%015%0.149CC..Hα-helixtrans-59.9-42176.900000111.9L588 I627 A628 R629 D635 V636 V639 L659 I667L588-A631 HydrophobicContact CD2-CB 3.96Å; I627-A631 WeakPolarHBondContact O-CB 3.31Å; I627-A631 PolarHBondContact O-N 3.33Å; A628-A631 PolarHBondContact O-N 3.17Å; R629-A631 PolarHBondContact O-N 2.9Å; A631-D635 PolarHBondContact O-N 3.26Å; A631-D635 VanDerWaalsContact O-N 3.1Å; A631-V636 HydrophobicContact CB-CG2 3.76Å; A631-V636 PolarHBondContact O-N 2.77Å; A631-V636 VanDerWaalsContact O-N 3.17Å; A631-V639 HydrophobicContact CB-CG2 3.63Å; A631-L659 HydrophobicContact CB-CD2 4.07Å; A631-I667 HydrophobicContact CB-CD1 4.29Å
632V97.8Very high97.5Very high33 Ų3330.6 Ų30.620%0.215%0.152CC..Hα-helixtrans-69.5-47178176.50000111.2A628 R629 L630 N634 D635 L659 W662 R664A628-V632 WeakPolarHBondContact O-CG2 3.38Å; A628-V632 PolarHBondContact O-N 3.2Å; A628-V632 VanDerWaalsContact O-N 3.07Å; R629-V632 PolarHBondContact O-N 2.91Å; L630-V632 VanDerWaalsContact C-N 3.31Å; L630-V632 PolarHBondContact O-N 2.95Å; V632-N634 VanDerWaalsContact C-N 3.31Å; V632-N634 PolarHBondContact O-N 2.83Å; V632-D635 PolarHBondContact O-N 2.8Å; V632-D635 VanDerWaalsContact O-N 3.16Å; V632-L659 HydrophobicContact CG2-CD2 4.42Å; V632-W662 HydrophobicContact CG1-CE3 4.41Å; V632-W662 HydrophobicContact CG2-CB 3.73Å; V632-W662 HydrophobicContact CG2-CD2 4.47Å; V632-W662 HydrophobicContact CG2-CG 4.02Å; V632-R664 HydrophobicContact CG1-CG 4.18Å; V632-R664 HydrophobicContact CG2-CB 4.08Å; V632-R664 HydrophobicContact CG2-CG 3.85Å
633E97.4Very high97.6Very high130 Ų13030.8 Ų30.861%0.60715%0.153SC*.Hα-helixtrans-63.2-36.2-179.5-75.4175.2178.700112.4R629 L630 D635R629-E633 WeakPolarHBondContact CD-OE1 3.44Å; R629-E633 HydrophobicContact CG-CG 4.26Å; R629-E633 VanDerWaalsContact CG-OE1 3.3Å; R629-E633 WeakPolarHBondContact CG-OE1 3.27Å; R629-E633 WeakPolarHBondContact O-CB 3.44Å; R629-E633 WeakPolarHBondContact O-CG 3.36Å; R629-E633 PolarHBondContact O-N 3.38Å; L630-E633 PolarHBondContact O-N 3.14Å; E633-D635 VanDerWaalsContact C-N 3.35Å
634N96.9Very high97.5Very high41 Ų4132.1 Ų32.122%0.21916%0.16CC..THydrogen-bonded Turntrans-85.9-7.1177.3-72.6-3.2000113.7R586 D616 L630 V632 V636R586-N634 WeakPolarHBondContact CD-O 3.34Å; R586-N634 VanDerWaalsContact CZ-O 3.26Å; R586-N634 PolarHBondContact NE-O 3.34Å; R586-N634 PolarHBondContact NH1-O 3.04Å; D616-N634 VanDerWaalsContact CG-ND2 3.26Å; D616-N634 PolarHBondContact OD2-ND2 3.46Å; L630-N634 VanDerWaalsContact O-CB 3.32Å; L630-N634 WeakPolarHBondContact O-CB 3.33Å; L630-N634 PolarHBondContact O-N 3.45Å; V632-N634 VanDerWaalsContact C-N 3.31Å; V632-N634 PolarHBondContact O-N 2.83Å; N634-V636 HydrophobicContact CB-CG1 3.81Å; N634-V636 PolarHBondContact O-N 2.92Å
635D97.2Very high97.3Very high59 Ų5932.3 Ų32.332%0.31616%0.162SC..THydrogen-bonded Turntrans5051.9-177.1-168.232000113.1R583 A631 V632 E633 R664R583-D635 IonicContact CZ-OD2 3.53Å; R583-D635 IonicContact NH1-OD2 3.76Å; R583-D635 PolarHBondContact NH1-OD2 3.01Å; R583-D635 IonicContact NH2-OD2 3.52Å; A631-D635 PolarHBondContact O-N 3.26Å; A631-D635 VanDerWaalsContact O-N 3.1Å; V632-D635 PolarHBondContact O-N 2.8Å; V632-D635 VanDerWaalsContact O-N 3.16Å; E633-D635 VanDerWaalsContact C-N 3.35Å; D635-R664 IonicContact OD1-CZ 2.66Å; D635-R664 VanDerWaalsContact OD1-CZ 3.32Å; D635-R664 IonicContact OD1-NH1 2.99Å; D635-R664 PolarHBondContact OD1-NH1 3.26Å; D635-R664 IonicContact OD1-NH2 3.32Å; D635-R664 PolarHBondContact OD1-NH2 2.97Å
636V98.1Very high97Very high0 Ų029.9 Ų29.90%016%0.157CC..  trans-75152.7-179.8-52.80000111.2R586 L588 A631 N634 V639 I667R586-V636 HydrophobicContact CG-CB 4.39Å; R586-V636 HydrophobicContact CG-CG1 4.01Å; L588-V636 HydrophobicContact CB-CG1 4.04Å; L588-V636 HydrophobicContact CB-CG2 4.19Å; A631-V636 HydrophobicContact CB-CG2 3.76Å; A631-V636 PolarHBondContact O-N 2.77Å; A631-V636 VanDerWaalsContact O-N 3.17Å; N634-V636 HydrophobicContact CB-CG1 3.81Å; N634-V636 PolarHBondContact O-N 2.92Å; V636-V639 HydrophobicContact CG2-CG2 4.05Å; V636-I667 HydrophobicContact CG2-CD1 4.46Å; V636-I667 HydrophobicContact CG2-CG2 4.05Å
637H98Very high96.8Very high5 Ų527 Ų272%0.02314%0.144CC..SBendtrans-83.8-29.3175.3-54.883000111.1F577 R583 R584 R586 C668 I709 H713F577-H637 AromaticContact CE1-NE2 3.9Å; F577-H637 AromaticContact CZ-CD2 3.9Å; F577-H637 AromaticContact CZ-NE2 3.79Å; R583-H637 VanDerWaalsContact CZ-CE1 3.5Å; R583-H637 VanDerWaalsContact CZ-NE2 3.33Å; R583-H637 PolarHBondContact NE-CE1 3.02Å; R583-H637 PolarHBondContact NE-NE2 2.99Å; R583-H637 PolarHBondContact NH2-CE1 3.33Å; R583-H637 PolarHBondContact NH2-NE2 2.91Å; R584-H637 PolarHBondContact O-CE1 2.72Å; R586-H637 PolarHBondContact N-ND1 2.78Å; R586-H637 PolarHBondContact O-N 3.08Å; H637-C668 PolarHBondContact O-N 3.04Å; H637-C668 VanDerWaalsContact O-N 3.12Å; H637-I709 HydrophobicContact CB-CB 4.33Å; H637-I709 HydrophobicContact CB-CD1 4.29Å; H637-I709 HydrophobicContact CB-CG2 4.14Å; H637-H713 AromaticContact CD2-CD2 3.75Å; H637-H713 AromaticContact CD2-NE2 3.37Å; H637-H713 PolarHBondContact CD2-NE2 3.47Å
638V98.3Very high96.6Very high0 Ų027.3 Ų27.30%015%0.146CC..EExtended strand (participates in β ladder)trans-147.5142.2-175.356.30000111.6R586 I587 L588 C668 V670 V705 I709R586-V638 PolarHBondContact O-N 3.22Å; I587-V638 WeakPolarHBondContact CA-O 3.09Å; I587-V638 HydrophobicContact CB-CG1 3.78Å; I587-V638 HydrophobicContact CD1-CG1 4.08Å; I587-V638 HydrophobicContact CG1-CG1 3.84Å; L588-V638 PolarHBondContact N-O 3.5Å; V638-C668 CarbonylContact C-O 3.31Å; V638-C668 VanDerWaalsContact CA-O 3.24Å; V638-C668 WeakPolarHBondContact CA-O 3.18Å; V638-C668 HydrophobicContact CB-CB 4.13Å; V638-C668 HydrophobicContact CG2-CB 4.09Å; V638-C668 WeakPolarHBondContact CG2-O 3.44Å; V638-V670 HydrophobicContact CG2-CG1 4.26Å; V638-V670 HydrophobicContact CG2-CG2 3.98Å; V638-V705 HydrophobicContact CG1-CG1 3.88Å; V638-V705 HydrophobicContact CG2-CG1 4.25Å; V638-I709 HydrophobicContact CB-CG2 3.87Å; V638-I709 HydrophobicContact CG1-CG2 4.08Å
639V98.6Very high96.4Very high0 Ų030.1 Ų30.10%016%0.158CC..EExtended strand (participates in β ladder)trans-106119.4167.2-177.90000108.9L588 A590 I627 A631 V636 L655 I667 C668 V670L588-V639 HydrophobicContact CB-CG2 4.39Å; L588-V639 HydrophobicContact CD2-CG2 4.45Å; L588-V639 CarbonylContact O-C 3.54Å; L588-V639 WeakPolarHBondContact O-CA 3.42Å; A590-V639 HydrophobicContact CB-CG1 3.88Å; I627-V639 HydrophobicContact CG2-CG1 3.99Å; A631-V639 HydrophobicContact CB-CG2 3.63Å; V636-V639 HydrophobicContact CG2-CG2 4.05Å; V639-L655 HydrophobicContact CG1-CD2 3.9Å; V639-I667 HydrophobicContact CG2-CG2 3.81Å; V639-C668 PolarHBondContact N-O 3.01Å; V639-V670 PolarHBondContact O-N 2.91Å
640G98.3Very high96.2Very high12 Ų1226 Ų2612%0.12415%0.146CC..EExtended strand (participates in β ladder)trans-93.799.2171.900000111L588 A590 S642L588-G640 PolarHBondContact O-N 2.91Å; A590-G640 PolarHBondContact N-O 2.74Å; G640-S642 PolarHBondContact O-N 3.37Å
641A98.2Very high96.1Very high1 Ų125 Ų251%0.00814%0.14CC..EExtended strand (participates in β ladder)trans-78.8104.1178.100000110.9M592 I652 V670 A671 G672M592-A641 HydrophobicContact CE-CB 3.78Å; A641-I652 HydrophobicContact CB-CD1 4.12Å; A641-I652 HydrophobicContact CB-CG1 4.1Å; A641-V670 PolarHBondContact N-O 2.71Å; A641-A671 WeakPolarHBondContact O-CA 3.48Å; A641-G672 PolarHBondContact O-N 2.92Å
642S97.7Very high96.1Very high16 Ų1625 Ų2511%0.11214%0.141CC..EExtended strand (participates in β ladder)trans-90.6104.4176.7-178.10000110.4A590 K591 G640 G672A590-S642 PolarHBondContact O-N 3.45Å; K591-S642 WeakPolarHBondContact CD-O 3.43Å; K591-S642 WeakPolarHBondContact CE-O 3.48Å; K591-S642 PolarHBondContact NZ-O 3.25Å; G640-S642 PolarHBondContact O-N 3.37Å; S642-G672 CarbonylContact C-O 3.5Å; S642-G672 WeakPolarHBondContact CA-O 3.46Å
643S96.6Very high96Very high12 Ų1224.4 Ų24.48%0.08414%0.137CC..  trans-120.2119.3-175.31770000111.6G672 G673 V674S643-G672 PolarHBondContact N-O 2.96Å; S643-G673 CarbonylContact O-C 3.44Å; S643-G673 WeakPolarHBondContact O-CA 3.4Å; S643-V674 PolarHBondContact O-N 3.5Å
644L94.6Very high96Very high52 Ų5222 Ų2227%0.27213%0.126SC..  trans-126.8-1.5179.9-66.889.4000112.9D595 H597 V674D595-L644 PolarHBondContact OD2-N 3.14Å; H597-L644 HydrophobicContact CB-CB 3.94Å; H597-L644 HydrophobicContact CB-CD1 4.16Å; H597-L644 HydrophobicContact CB-CD2 3.94Å; H597-L644 HydrophobicContact CB-CG 4.23Å; L644-V674 HydrophobicContact CD2-CG2 4.45Å; L644-V674 HydrophobicContact CG-CG2 4.45Å
645A92.3Very high96Very high8 Ų820 Ų207%0.06612%0.116CC..SBendtrans-109.523.9-176.100000114.2L108 D595 G647L108-A645 HydrophobicContact CD1-CB 3.52Å; D595-A645 HydrophobicContact CB-CB 3.76Å; A645-G647 PolarHBondContact O-N 3.05Å; A645-G647 VanDerWaalsContact O-N 3.09Å
646A91.3Very high96.1Very high40 Ų4018.6 Ų18.633%0.33111%0.109SC..SBendtrans60.215178.400000116.6K127 H648K127-A646 HydrophobicContact CD-CB 4.28Å; K127-A646 WeakPolarHBondContact CE-O 3.33Å; A646-H648 VanDerWaalsContact C-N 3.32Å
647G92Very high96.1Very high2 Ų223.3 Ų23.32%0.02113%0.131CC..  trans-82.6-1.7175.600000114.6A645 K649 T650 L651A645-G647 PolarHBondContact O-N 3.05Å; A645-G647 VanDerWaalsContact O-N 3.09Å; G647-K649 VanDerWaalsContact C-N 3.35Å; G647-K649 PolarHBondContact O-N 2.87Å; G647-T650 PolarHBondContact O-N 3.44Å; G647-T650 VanDerWaalsContact O-N 3.08Å; G647-L651 WeakPolarHBondContact O-CG 3.3Å; G647-L651 PolarHBondContact O-N 3.24Å
648H94.8Very high96.1Very high6 Ų623.2 Ų23.23%0.02813%0.131CC..Hα-helixtrans-60.4-35.8-170.250.3-77.8000114.2A646 T650 I652 P653 I675 D679A646-H648 VanDerWaalsContact C-N 3.32Å; H648-T650 PolarHBondContact O-N 3.24Å; H648-I652 HydrophobicContact CB-CD1 3.77Å; H648-I652 HydrophobicContact CB-CG1 4.36Å; H648-I652 WeakPolarHBondContact O-CB 3.18Å; H648-I652 PolarHBondContact O-N 3.03Å; H648-P653 WeakPolarHBondContact O-CD 3.39Å; H648-I675 HydrophobicContact CB-CG1 4.42Å; H648-D679 IonicContact CD2-OD2 3.23Å; H648-D679 IonicContact CE1-OD2 2.95Å; H648-D679 IonicContact NE2-OD2 2.94Å; H648-D679 PolarHBondContact NE2-OD2 3.02Å
649K93.8Very high96.1Very high59 Ų5923.4 Ų23.426%0.25713%0.132SC..Hα-helixtrans-67.5-16.1178.4-67.4176.588152.80113.7E471 G647 D679 F682E471-K649 IonicContact OE1-NZ 3.73Å; E471-K649 PolarHBondContact OE1-NZ 2.97Å; G647-K649 VanDerWaalsContact C-N 3.35Å; G647-K649 PolarHBondContact O-N 2.87Å; K649-D679 WeakPolarHBondContact CD-OD1 3.49Å; K649-D679 WeakPolarHBondContact CE-OD1 3.41Å; K649-D679 IonicContact NZ-OD1 3.68Å; K649-D679 PolarHBondContact NZ-OD1 2.6Å; K649-F682 HydrophobicContact CB-CE1 3.91Å; K649-F682 HydrophobicContact CB-CZ 4.31Å; K649-F682 HydrophobicContact CG-CD1 4.16Å; K649-F682 HydrophobicContact CG-CE1 4.06Å
650T93.2Very high96Very high33 Ų3328.2 Ų28.220%0.20215%0.153CC..Hα-helixtrans-106.5-56.1177.9-55.10000110.7G647 H648 P653 E654G647-T650 PolarHBondContact O-N 3.44Å; G647-T650 VanDerWaalsContact O-N 3.08Å; H648-T650 PolarHBondContact O-N 3.24Å; T650-P653 WeakPolarHBondContact O-CD 3.5Å; T650-E654 WeakPolarHBondContact O-CG 3.29Å; T650-E654 PolarHBondContact O-N 3.15Å
651L95.7Very high95.9Very high15 Ų1535.3 Ų35.38%0.07918%0.18CC..Hα-helixtrans-73.3-36.7-167.2-60.5172000113.6M592 P624 G647 E654 L655M592-L651 HydrophobicContact CB-CB 4.26Å; M592-L651 HydrophobicContact CB-CD1 4.1Å; M592-L651 HydrophobicContact CE-CB 4.36Å; P624-L651 HydrophobicContact CG-CB 4.3Å; P624-L651 HydrophobicContact CG-CD2 3.97Å; P624-L651 WeakPolarHBondContact CG-O 3.42Å; G647-L651 WeakPolarHBondContact O-CG 3.3Å; G647-L651 PolarHBondContact O-N 3.24Å; L651-E654 PolarHBondContact O-N 2.76Å; L651-L655 PolarHBondContact O-N 3.15Å
652I97.4Very high95.9Very high1 Ų141.7 Ų41.71%0.00520%0.204CC..Hα-helixtrans-71.7-45.6-179.3-59.2177.3000111.1M592 A641 H648 E654 L655 V656 V669 A671 L683 V688M592-I652 HydrophobicContact CE-CG1 3.9Å; A641-I652 HydrophobicContact CB-CD1 4.12Å; A641-I652 HydrophobicContact CB-CG1 4.1Å; H648-I652 HydrophobicContact CB-CD1 3.77Å; H648-I652 HydrophobicContact CB-CG1 4.36Å; H648-I652 WeakPolarHBondContact O-CB 3.18Å; H648-I652 PolarHBondContact O-N 3.03Å; I652-E654 VanDerWaalsContact C-N 3.31Å; I652-E654 PolarHBondContact O-N 2.7Å; I652-L655 WeakPolarHBondContact O-CB 3.39Å; I652-L655 PolarHBondContact O-N 2.97Å; I652-L655 VanDerWaalsContact O-N 3.15Å; I652-V656 PolarHBondContact O-N 2.83Å; I652-V656 VanDerWaalsContact O-N 3.07Å; I652-V669 HydrophobicContact CG2-CG1 4.22Å; I652-A671 HydrophobicContact CD1-CB 3.78Å; I652-L683 HydrophobicContact CB-CD2 4.28Å; I652-L683 HydrophobicContact CG2-CD2 4.49Å; I652-V688 HydrophobicContact CG2-CG2 3.44Å; I652-V688 VanDerWaalsContact CG2-CG2 3.44Å
653P96.6Very high95.8Very high20 Ų2043.7 Ų43.713%0.1323%0.228CC..Hα-helixtrans-56-42.4170.3-31.439.1000113.9H648 T650 L655 V656 E657 F682 R686H648-P653 WeakPolarHBondContact O-CD 3.39Å; T650-P653 WeakPolarHBondContact O-CD 3.5Å; P653-L655 VanDerWaalsContact C-N 3.29Å; P653-L655 PolarHBondContact O-N 3.41Å; P653-V656 PolarHBondContact O-N 2.89Å; P653-E657 WeakPolarHBondContact O-CG 3.35Å; P653-E657 PolarHBondContact O-N 2.96Å; P653-F682 HydrophobicContact CG-CE1 4.03Å; P653-R686 HydrophobicContact CG-CB 4.5Å
654E96.4Very high95.8Very high80 Ų8045.2 Ų45.237%0.37423%0.232SC..Hα-helixtrans-62.7-35.2176.6-75.6175.2177.800112.3P624 T650 L651 I652 A658P624-E654 HydrophobicContact CB-CB 3.79Å; P624-E654 HydrophobicContact CG-CB 3.79Å; T650-E654 WeakPolarHBondContact O-CG 3.29Å; T650-E654 PolarHBondContact O-N 3.15Å; L651-E654 PolarHBondContact O-N 2.76Å; I652-E654 VanDerWaalsContact C-N 3.31Å; I652-E654 PolarHBondContact O-N 2.7Å; E654-A658 VanDerWaalsContact O-CB 3.25Å; E654-A658 WeakPolarHBondContact O-CB 3.34Å; E654-A658 PolarHBondContact O-N 3.23Å
655L98Very high95.8Very high0 Ų049 Ų490%025%0.248CC..Hα-helixtrans-65.2-47175168.563.3000111.4M592 P624 I627 A628 V639 L651 I652 P653 E657 A658 L659 V669M592-L655 HydrophobicContact CE-CB 4.39Å; M592-L655 HydrophobicContact CE-CD2 3.92Å; M592-L655 HydrophobicContact SD-CB 3.9Å; M592-L655 HydrophobicContact SD-CD2 3.92Å; M592-L655 HydrophobicContact SD-CG 4.38Å; P624-L655 HydrophobicContact CB-CB 4.11Å; I627-L655 HydrophobicContact CB-CD1 4Å; I627-L655 HydrophobicContact CG2-CD1 3.59Å; I627-L655 HydrophobicContact CG2-CD2 4.23Å; A628-L655 HydrophobicContact CB-CD1 4.14Å; V639-L655 HydrophobicContact CG1-CD2 3.9Å; L651-L655 PolarHBondContact O-N 3.15Å; I652-L655 WeakPolarHBondContact O-CB 3.39Å; I652-L655 PolarHBondContact O-N 2.97Å; I652-L655 VanDerWaalsContact O-N 3.15Å; P653-L655 VanDerWaalsContact C-N 3.29Å; P653-L655 PolarHBondContact O-N 3.41Å; L655-E657 VanDerWaalsContact C-N 3.33Å; L655-E657 PolarHBondContact O-N 3.25Å; L655-A658 PolarHBondContact O-N 3.39Å; L655-A658 VanDerWaalsContact O-N 3.15Å; L655-L659 HydrophobicContact CD1-CD1 4.21Å; L655-L659 HydrophobicContact CD1-CG 4.2Å; L655-L659 HydrophobicContact CG-CD1 4.31Å; L655-L659 WeakPolarHBondContact O-CG 3.37Å; L655-L659 PolarHBondContact O-N 3.25Å; L655-V669 HydrophobicContact CD2-CG1 4.24Å
656V98.2Very high95.9Very high28 Ų2851.9 Ų51.917%0.1726%0.262CS..Hα-helixtrans-60.6-45.7178.3176.30000110.3I652 P653 A658 L659 K660 V669 R686I652-V656 PolarHBondContact O-N 2.83Å; I652-V656 VanDerWaalsContact O-N 3.07Å; P653-V656 PolarHBondContact O-N 2.89Å; V656-A658 VanDerWaalsContact C-N 3.31Å; V656-A658 PolarHBondContact O-N 3.37Å; V656-L659 PolarHBondContact O-N 3.13Å; V656-K660 WeakPolarHBondContact O-CB 3.18Å; V656-K660 PolarHBondContact O-N 3.31Å; V656-V669 HydrophobicContact CG2-CB 4.25Å; V656-V669 HydrophobicContact CG2-CG1 4.28Å; V656-V669 HydrophobicContact CG2-CG2 4.09Å; V656-R686 WeakPolarHBondContact CG1-O 3.38Å
657E97.6Very high96.2Very high100 Ų10050.3 Ų50.347%0.46725%0.248SC..Hα-helixtrans-64.7-33.9175.7-71.2-60.3139.100112.6P653 L655 K660 K661P653-E657 WeakPolarHBondContact O-CG 3.35Å; P653-E657 PolarHBondContact O-N 2.96Å; L655-E657 VanDerWaalsContact C-N 3.33Å; L655-E657 PolarHBondContact O-N 3.25Å; E657-K660 WeakPolarHBondContact O-CB 3.35Å; E657-K661 VanDerWaalsContact O-CG 3.31Å; E657-K661 WeakPolarHBondContact O-CG 3.36Å; E657-K661 PolarHBondContact O-N 2.81Å
658A97.8Very high96.4Very high3 Ų350.9 Ų50.93%0.02525%0.252CS..Hα-helixtrans-67.4-46.1174.800000111.7E625 A628 E654 L655 V656 K660 K661 W662E625-A658 HydrophobicContact CG-CB 4.5Å; A628-A658 HydrophobicContact CB-CB 3.52Å; E654-A658 VanDerWaalsContact O-CB 3.25Å; E654-A658 WeakPolarHBondContact O-CB 3.34Å; E654-A658 PolarHBondContact O-N 3.23Å; L655-A658 PolarHBondContact O-N 3.39Å; L655-A658 VanDerWaalsContact O-N 3.15Å; V656-A658 VanDerWaalsContact C-N 3.31Å; V656-A658 PolarHBondContact O-N 3.37Å; A658-K660 VanDerWaalsContact C-N 3.26Å; A658-K660 PolarHBondContact O-N 3.41Å; A658-K661 WeakPolarHBondContact O-CB 3.47Å; A658-K661 PolarHBondContact O-N 3.43Å; A658-K661 VanDerWaalsContact O-N 3.1Å; A658-W662 PolarHBondContact O-N 2.85Å; A658-W662 VanDerWaalsContact O-N 3.13Å
659L98.3Very high96.6Very high4 Ų450.9 Ų50.92%0.02125%0.252CS..Hα-helixtrans-57.8-41174.7-73.5169.6000111.7A628 A631 V632 L655 V656 W662 G663 R664 I667 V669A628-L659 HydrophobicContact CB-CD2 4.04Å; A628-L659 HydrophobicContact CB-CG 4.14Å; A631-L659 HydrophobicContact CB-CD2 4.07Å; V632-L659 HydrophobicContact CG2-CD2 4.42Å; L655-L659 HydrophobicContact CD1-CD1 4.21Å; L655-L659 HydrophobicContact CD1-CG 4.2Å; L655-L659 HydrophobicContact CG-CD1 4.31Å; L655-L659 WeakPolarHBondContact O-CG 3.37Å; L655-L659 PolarHBondContact O-N 3.25Å; V656-L659 PolarHBondContact O-N 3.13Å; L659-W662 CarbonylContact O-C 3.6Å; L659-W662 PolarHBondContact O-N 3.39Å; L659-W662 VanDerWaalsContact O-N 3.13Å; L659-G663 PolarHBondContact O-N 3.05Å; L659-R664 PolarHBondContact O-N 2.95Å; L659-I667 HydrophobicContact CD1-CB 4.47Å; L659-I667 HydrophobicContact CD1-CG2 4.37Å; L659-I667 HydrophobicContact CD2-CB 4.43Å; L659-I667 HydrophobicContact CD2-CD1 4.1Å; L659-V669 HydrophobicContact CD1-CG2 3.53Å
660K97.2Very high96.8Very high100 Ų10048.2 Ų48.244%0.43524%0.241SC..Hα-helixtrans-59.5-44.4173175.3158.8-169.1173.30113.2V656 E657 A658 W662 G663 E665V656-K660 WeakPolarHBondContact O-CB 3.18Å; V656-K660 PolarHBondContact O-N 3.31Å; E657-K660 WeakPolarHBondContact O-CB 3.35Å; A658-K660 VanDerWaalsContact C-N 3.26Å; A658-K660 PolarHBondContact O-N 3.41Å; K660-W662 PolarHBondContact O-N 3.46Å; K660-G663 PolarHBondContact O-N 3.01Å; K660-E665 HydrophobicContact CB-CG 3.85Å; K660-E665 HydrophobicContact CD-CG 4.35Å; K660-E665 WeakPolarHBondContact CE-OE1 3.39Å; K660-E665 HydrophobicContact CG-CG 3.93Å; K660-E665 WeakPolarHBondContact CG-OE1 3.18Å
661K97.3Very high97Very high162 Ų16246.8 Ų46.870%0.70423%0.232SC*.Hα-helixtrans-62.1-29.4175.1-71.1167.5-170168.50112.8E657 A658 G663E657-K661 VanDerWaalsContact O-CG 3.31Å; E657-K661 WeakPolarHBondContact O-CG 3.36Å; E657-K661 PolarHBondContact O-N 2.81Å; A658-K661 WeakPolarHBondContact O-CB 3.47Å; A658-K661 PolarHBondContact O-N 3.43Å; A658-K661 VanDerWaalsContact O-N 3.1Å; K661-G663 VanDerWaalsContact C-N 3.28Å
662W96.2Very high97.1Very high134 Ų13446.7 Ų46.751%0.50824%0.235SC..THydrogen-bonded Turntrans-81.7-2.1173.2-75.9101000113.9R629 V632 A658 L659 K660 R664R629-W662 HydrophobicContact CB-CZ2 4.07Å; R629-W662 HydrophobicContact CG-CH2 4.34Å; R629-W662 HydrophobicContact CG-CZ2 4.05Å; V632-W662 HydrophobicContact CG1-CE3 4.41Å; V632-W662 HydrophobicContact CG2-CB 3.73Å; V632-W662 HydrophobicContact CG2-CD2 4.47Å; V632-W662 HydrophobicContact CG2-CG 4.02Å; A658-W662 PolarHBondContact O-N 2.85Å; A658-W662 VanDerWaalsContact O-N 3.13Å; L659-W662 CarbonylContact O-C 3.6Å; L659-W662 PolarHBondContact O-N 3.39Å; L659-W662 VanDerWaalsContact O-N 3.13Å; K660-W662 PolarHBondContact O-N 3.46Å; W662-R664 VanDerWaalsContact C-N 3.29Å; W662-R664 PolarHBondContact O-N 2.93Å
663G96.7Very high97Very high59 Ų5947.5 Ų47.561%0.60824%0.243SC*.THydrogen-bonded Turntrans70.723.5-178.400000113.6L659 K660 K661L659-G663 PolarHBondContact O-N 3.05Å; K660-G663 PolarHBondContact O-N 3.01Å; K661-G663 VanDerWaalsContact C-N 3.28Å
664R96.5Very high96.8Very high44 Ų4448.4 Ų48.417%0.16625%0.248CC..  trans-116.648.4-179.6-70.1-59.4-56.4-86.95.6111.9V632 D635 L659 W662 D666 I667V632-R664 HydrophobicContact CG1-CG 4.18Å; V632-R664 HydrophobicContact CG2-CB 4.08Å; V632-R664 HydrophobicContact CG2-CG 3.85Å; D635-R664 IonicContact OD1-CZ 2.66Å; D635-R664 VanDerWaalsContact OD1-CZ 3.32Å; D635-R664 IonicContact OD1-NH1 2.99Å; D635-R664 PolarHBondContact OD1-NH1 3.26Å; D635-R664 IonicContact OD1-NH2 3.32Å; D635-R664 PolarHBondContact OD1-NH2 2.97Å; L659-R664 PolarHBondContact O-N 2.95Å; W662-R664 VanDerWaalsContact C-N 3.29Å; W662-R664 PolarHBondContact O-N 2.93Å; R664-D666 VanDerWaalsContact C-OD1 3.26Å; R664-D666 WeakPolarHBondContact CA-OD1 3.47Å; R664-D666 WeakPolarHBondContact CD-OD1 3.31Å; R664-D666 IonicContact CZ-OD1 3.58Å; R664-D666 IonicContact CZ-OD2 3.63Å; R664-D666 IonicContact NE-OD1 3.93Å; R664-D666 PolarHBondContact NE-OD1 2.85Å; R664-D666 IonicContact NE-OD2 2.71Å; R664-D666 PolarHBondContact NE-OD2 3.2Å; R664-D666 VanDerWaalsContact NE-OD2 3.12Å; R664-D666 IonicContact NH2-OD1 3.81Å; R664-D666 IonicContact NH2-OD2 3.38Å; R664-D666 PolarHBondContact NH2-OD2 3.22Å; R664-D666 PolarHBondContact O-N 3.38Å; R664-I667 HydrophobicContact CB-CD1 3.78Å; R664-I667 HydrophobicContact CB-CG1 4.05Å; R664-I667 HydrophobicContact CG-CD1 4.3Å; R664-I667 PolarHBondContact O-N 3.3Å
665E94.4Very high96.7Very high132 Ų13244.7 Ų44.762%0.61723%0.231SC*.THydrogen-bonded Turntrans-64-13.4173.8-61.6-178-139.400112.3K660 I667K660-E665 HydrophobicContact CB-CG 3.85Å; K660-E665 HydrophobicContact CD-CG 4.35Å; K660-E665 WeakPolarHBondContact CE-OE1 3.39Å; K660-E665 HydrophobicContact CG-CG 3.93Å; K660-E665 WeakPolarHBondContact CG-OE1 3.18Å; E665-I667 VanDerWaalsContact C-N 3.32Å
666D94.9Very high96.2Very high68 Ų6845.3 Ų45.336%0.36424%0.235SC..THydrogen-bonded Turntrans-71.5-22.4173.363-62.6000113.5R664 C668R664-D666 VanDerWaalsContact C-OD1 3.26Å; R664-D666 WeakPolarHBondContact CA-OD1 3.47Å; R664-D666 WeakPolarHBondContact CD-OD1 3.31Å; R664-D666 IonicContact CZ-OD1 3.58Å; R664-D666 IonicContact CZ-OD2 3.63Å; R664-D666 IonicContact NE-OD1 3.93Å; R664-D666 PolarHBondContact NE-OD1 2.85Å; R664-D666 IonicContact NE-OD2 2.71Å; R664-D666 PolarHBondContact NE-OD2 3.2Å; R664-D666 VanDerWaalsContact NE-OD2 3.12Å; R664-D666 IonicContact NH2-OD1 3.81Å; R664-D666 IonicContact NH2-OD2 3.38Å; R664-D666 PolarHBondContact NH2-OD2 3.22Å; R664-D666 PolarHBondContact O-N 3.38Å; D666-C668 PolarHBondContact O-N 3.07Å
667I97.2Very high95.8Very high7 Ų747 Ų474%0.03625%0.247CC..SBendtrans-71.9114.3179.1-62.6-179.9000108.9A631 V636 V639 L659 R664 E665A631-I667 HydrophobicContact CB-CD1 4.29Å; V636-I667 HydrophobicContact CG2-CD1 4.46Å; V636-I667 HydrophobicContact CG2-CG2 4.05Å; V639-I667 HydrophobicContact CG2-CG2 3.81Å; L659-I667 HydrophobicContact CD1-CB 4.47Å; L659-I667 HydrophobicContact CD1-CG2 4.37Å; L659-I667 HydrophobicContact CD2-CB 4.43Å; L659-I667 HydrophobicContact CD2-CD1 4.1Å; R664-I667 HydrophobicContact CB-CD1 3.78Å; R664-I667 HydrophobicContact CB-CG1 4.05Å; R664-I667 HydrophobicContact CG-CD1 4.3Å; R664-I667 PolarHBondContact O-N 3.3Å; E665-I667 VanDerWaalsContact C-N 3.32Å
668C96.7Very high95.4Very high13 Ų1347.7 Ų47.79%0.08825%0.25CS..EExtended strand (participates in β ladder)trans-64.6137.7179.3-178.40000110.9H637 V638 V639 D666 A689 I709H637-C668 PolarHBondContact O-N 3.04Å; H637-C668 VanDerWaalsContact O-N 3.12Å; V638-C668 CarbonylContact C-O 3.31Å; V638-C668 VanDerWaalsContact CA-O 3.24Å; V638-C668 WeakPolarHBondContact CA-O 3.18Å; V638-C668 HydrophobicContact CB-CB 4.13Å; V638-C668 HydrophobicContact CG2-CB 4.09Å; V638-C668 WeakPolarHBondContact CG2-O 3.44Å; V639-C668 PolarHBondContact N-O 3.01Å; D666-C668 PolarHBondContact O-N 3.07Å; C668-A689 WeakPolarHBondContact SG-CB 3.49Å; C668-I709 HydrophobicContact CB-CG2 4.43Å
669V98.3Very high95.1Very high6 Ų648.3 Ų48.34%0.03625%0.253CS..EExtended strand (participates in β ladder)trans-114.4120.7173.5-179.70000109.1I652 L655 V656 L659 V688 A689I652-V669 HydrophobicContact CG2-CG1 4.22Å; L655-V669 HydrophobicContact CD2-CG1 4.24Å; V656-V669 HydrophobicContact CG2-CB 4.25Å; V656-V669 HydrophobicContact CG2-CG1 4.28Å; V656-V669 HydrophobicContact CG2-CG2 4.09Å; L659-V669 HydrophobicContact CD1-CG2 3.53Å; V669-V688 CarbonylContact O-C 3.55Å; V669-V688 WeakPolarHBondContact O-CA 3.41Å; V669-A689 PolarHBondContact O-N 2.72Å
670V98.3Very high94.9Very high4 Ų450.7 Ų50.72%0.02426%0.262CS..EExtended strand (participates in β ladder)trans-116.4149.7171.5-59.30000109.6V638 V639 A641 A689 A690 Y692 V705 L708V638-V670 HydrophobicContact CG2-CG1 4.26Å; V638-V670 HydrophobicContact CG2-CG2 3.98Å; V639-V670 PolarHBondContact O-N 2.91Å; A641-V670 PolarHBondContact N-O 2.71Å; V670-A689 HydrophobicContact CG1-CB 4.39Å; V670-A690 WeakPolarHBondContact CA-O 3.48Å; V670-A690 HydrophobicContact CG1-CB 4.05Å; V670-Y692 HydrophobicContact CB-CE2 3.97Å; V670-Y692 HydrophobicContact CG1-CE2 4.32Å; V670-Y692 HydrophobicContact CG2-CE2 4.16Å; V670-V705 HydrophobicContact CG1-CG2 4.35Å; V670-V705 HydrophobicContact CG2-CG2 4.27Å; V670-L708 HydrophobicContact CG1-CD1 4.22Å
671A98.3Very high94.8Very high2 Ų248.5 Ų48.52%0.01726%0.262CS..EExtended strand (participates in β ladder)trans-115.5148.9-179.400000111A641 I652 I675 V688 A690 I691 Y692A641-A671 WeakPolarHBondContact O-CA 3.48Å; I652-A671 HydrophobicContact CD1-CB 3.78Å; A671-I675 HydrophobicContact CB-CD1 3.69Å; A671-V688 HydrophobicContact CB-CG1 3.91Å; A671-A690 PolarHBondContact N-O 2.85Å; A671-I691 HydrophobicContact CB-CG1 4.37Å; A671-I691 CarbonylContact O-C 3.46Å; A671-I691 VanDerWaalsContact O-CA 3.3Å; A671-I691 WeakPolarHBondContact O-CA 3.46Å; A671-Y692 PolarHBondContact O-N 3.2Å
672G97Very high94.8Very high14 Ų1443.3 Ų43.314%0.14424%0.24CC..EExtended strand (participates in β ladder)trans-155.1165.2170.300000112.7A641 S642 S643 Y692A641-G672 PolarHBondContact O-N 2.92Å; S642-G672 CarbonylContact C-O 3.5Å; S642-G672 WeakPolarHBondContact CA-O 3.46Å; S643-G672 PolarHBondContact N-O 2.96Å; G672-Y692 WeakPolarHBondContact CA-O 3.43Å
673G94.9Very high94.9Very high17 Ų1737 Ų3718%0.17522%0.216CC..SBendtrans108.9-159.6-17300000112S643 I675 Y692 P694S643-G673 CarbonylContact O-C 3.44Å; S643-G673 WeakPolarHBondContact O-CA 3.4Å; G673-I675 PolarHBondContact O-N 2.98Å; G673-Y692 PolarHBondContact N-O 3.11Å; G673-P694 WeakPolarHBondContact O-CD 3.41Å
674V93.6Very high94.9Very high39 Ų3939.1 Ų39.124%0.23621%0.21CC..SBendtrans-78.989.8-175.6-176.70000109.3S643 L644 P694S643-V674 PolarHBondContact O-N 3.5Å; L644-V674 HydrophobicContact CD2-CG2 4.45Å; L644-V674 HydrophobicContact CG-CG2 4.45Å; V674-P694 HydrophobicContact CG2-CG 4.46Å
675I92.7Very high94.9Very high2 Ų244.5 Ų44.51%0.0124%0.237CC..  trans-120.1116.1175.3-60.1172.8000106H648 A671 G673 D679 Y680 L683 I691H648-I675 HydrophobicContact CB-CG1 4.42Å; A671-I675 HydrophobicContact CB-CD1 3.69Å; G673-I675 PolarHBondContact O-N 2.98Å; I675-D679 HydrophobicContact CG2-CB 4.21Å; I675-Y680 HydrophobicContact CB-CE1 4.03Å; I675-Y680 HydrophobicContact CG2-CD1 3.81Å; I675-Y680 HydrophobicContact CG2-CE1 3.68Å; I675-Y680 WeakPolarHBondContact O-CE1 3.45Å; I675-L683 HydrophobicContact CD1-CD1 4.1Å; I675-L683 HydrophobicContact CG2-CD1 3.8Å; I675-I691 HydrophobicContact CB-CG2 4.49Å; I675-I691 HydrophobicContact CD1-CG2 4.01Å
676P88.7Confident95Very high13 Ų1343.1 Ų43.18%0.08423%0.226CC..  trans-61.1139177.3-22.132.4000111.1Q678 D679 Y680P676-Q678 HydrophobicContact CB-CG 4.1Å; P676-Q678 VanDerWaalsContact CB-NE2 3.26Å; P676-Q678 VanDerWaalsContact CB-OE1 3.29Å; P676-Q678 PolarHBondContact O-N 3.1Å; P676-D679 PolarHBondContact O-N 2.92Å; P676-Y680 WeakPolarHBondContact O-CD1 3.41Å
677P88.6Confident95.1Very high65 Ų6542 Ų4242%0.42223%0.231SC..G310 helixtrans-51.7-33.6-179.6-3136.8000114.5E327 D679 Y680E327-P677 WeakPolarHBondContact OE1-CG 3.32Å; P677-D679 PolarHBondContact O-N 3.43Å; P677-Y680 WeakPolarHBondContact O-CB 3.35Å; P677-Y680 PolarHBondContact O-N 3.32Å; P677-Y680 VanDerWaalsContact O-N 3.11Å
678Q89.1Confident95.1Very high114 Ų11442 Ų4253%0.53323%0.231SC..G310 helixtrans-62.6-20.8176.962.7-90.827.500114.5P676P676-Q678 HydrophobicContact CB-CG 4.1Å; P676-Q678 VanDerWaalsContact CB-NE2 3.26Å; P676-Q678 VanDerWaalsContact CB-OE1 3.29Å; P676-Q678 PolarHBondContact O-N 3.1Å
679D92.4Very high95.1Very high15 Ų1543.6 Ų43.68%0.0825%0.245CC..G310 helixtrans-89.8-5.3178.2-71.5-30000112.8H648 K649 I675 P676 P677 F682 L683H648-D679 IonicContact CD2-OD2 3.23Å; H648-D679 IonicContact CE1-OD2 2.95Å; H648-D679 IonicContact NE2-OD2 2.94Å; H648-D679 PolarHBondContact NE2-OD2 3.02Å; K649-D679 WeakPolarHBondContact CD-OD1 3.49Å; K649-D679 WeakPolarHBondContact CE-OD1 3.41Å; K649-D679 IonicContact NZ-OD1 3.68Å; K649-D679 PolarHBondContact NZ-OD1 2.6Å; I675-D679 HydrophobicContact CG2-CB 4.21Å; P676-D679 PolarHBondContact O-N 2.92Å; P677-D679 PolarHBondContact O-N 3.43Å; D679-F682 WeakPolarHBondContact O-CB 3.43Å; D679-F682 PolarHBondContact O-N 3.2Å; D679-L683 PolarHBondContact O-N 3.07Å
680Y94.1Very high95.1Very high55 Ų5543.8 Ų43.822%0.21625%0.247CC..Hα-helixtrans-64.5-48.2-172.8-79.528.4000111.8I675 P676 P677 F682 L683 Q684 I691I675-Y680 HydrophobicContact CB-CE1 4.03Å; I675-Y680 HydrophobicContact CG2-CD1 3.81Å; I675-Y680 HydrophobicContact CG2-CE1 3.68Å; I675-Y680 WeakPolarHBondContact O-CE1 3.45Å; P676-Y680 WeakPolarHBondContact O-CD1 3.41Å; P677-Y680 WeakPolarHBondContact O-CB 3.35Å; P677-Y680 PolarHBondContact O-N 3.32Å; P677-Y680 VanDerWaalsContact O-N 3.11Å; Y680-F682 VanDerWaalsContact C-N 3.29Å; Y680-F682 PolarHBondContact O-N 2.9Å; Y680-L683 PolarHBondContact O-N 3.49Å; Y680-Q684 WeakPolarHBondContact O-CG 3.5Å; Y680-Q684 PolarHBondContact O-N 3.22Å; Y680-I691 HydrophobicContact CD1-CD1 3.89Å; Y680-I691 HydrophobicContact CD1-CG2 4.08Å; Y680-I691 HydrophobicContact CD2-CB 4.19Å; Y680-I691 HydrophobicContact CD2-CD1 4.01Å; Y680-I691 HydrophobicContact CD2-CG2 4.28Å; Y680-I691 HydrophobicContact CE1-CG2 3.63Å; Y680-I691 HydrophobicContact CE2-CB 4.03Å; Y680-I691 HydrophobicContact CE2-CG2 3.84Å; Y680-I691 HydrophobicContact CG-CD1 3.61Å; Y680-I691 HydrophobicContact CG-CG2 4.4Å
681A95.8Very high95Very high53 Ų5344.7 Ų44.744%0.43825%0.252SS..Hα-helixtrans-59.3-42178.600000111.5L683 Q684 E685A681-L683 VanDerWaalsContact C-N 3.31Å; A681-L683 PolarHBondContact O-N 3.12Å; A681-Q684 PolarHBondContact O-N 3.44Å; A681-E685 WeakPolarHBondContact O-CB 3.42Å; A681-E685 VanDerWaalsContact O-CG 3.27Å; A681-E685 WeakPolarHBondContact O-CG 3.3Å; A681-E685 PolarHBondContact O-N 3.21Å
682F96.5Very high94.9Very high54 Ų5446.2 Ų46.224%0.23726%0.257CS..Hα-helixtrans-59.4-40.7178.1170.6-83.8000112.7K649 P653 D679 Y680 R686K649-F682 HydrophobicContact CB-CE1 3.91Å; K649-F682 HydrophobicContact CB-CZ 4.31Å; K649-F682 HydrophobicContact CG-CD1 4.16Å; K649-F682 HydrophobicContact CG-CE1 4.06Å; P653-F682 HydrophobicContact CG-CE1 4.03Å; D679-F682 WeakPolarHBondContact O-CB 3.43Å; D679-F682 PolarHBondContact O-N 3.2Å; Y680-F682 VanDerWaalsContact C-N 3.29Å; Y680-F682 PolarHBondContact O-N 2.9Å; F682-R686 VanDerWaalsContact CZ-CZ 3.44Å; F682-R686 PolarHBondContact O-NH1 3.03Å; F682-R686 VanDerWaalsContact O-NH1 3.1Å
683L97.5Very high94.7Very high0 Ų046 Ų460%026%0.255CS..Hα-helixtrans-74-42.9179.2-70.4178.2000111.6I652 I675 D679 Y680 A681 R686 G687 V688 I691I652-L683 HydrophobicContact CB-CD2 4.28Å; I652-L683 HydrophobicContact CG2-CD2 4.49Å; I675-L683 HydrophobicContact CD1-CD1 4.1Å; I675-L683 HydrophobicContact CG2-CD1 3.8Å; D679-L683 PolarHBondContact O-N 3.07Å; Y680-L683 PolarHBondContact O-N 3.49Å; A681-L683 VanDerWaalsContact C-N 3.31Å; A681-L683 PolarHBondContact O-N 3.12Å; L683-R686 CarbonylContact O-C 3.59Å; L683-R686 PolarHBondContact O-N 3.09Å; L683-G687 PolarHBondContact O-N 3.44Å; L683-V688 HydrophobicContact CB-CB 4.2Å; L683-V688 HydrophobicContact CB-CG2 3.98Å; L683-V688 WeakPolarHBondContact O-CB 3.38Å; L683-V688 WeakPolarHBondContact O-CG2 3.27Å; L683-V688 PolarHBondContact O-N 3.3Å; L683-I691 HydrophobicContact CB-CD1 4.05Å; L683-I691 HydrophobicContact CD1-CD1 4.11Å
684Q97.2Very high94.6Very high104 Ų10447 Ų4749%0.48626%0.259SS..Hα-helixtrans-62.1-43.3177.8-72.8173.8-26.700112Y680 A681 R686 G687 I691Y680-Q684 WeakPolarHBondContact O-CG 3.5Å; Y680-Q684 PolarHBondContact O-N 3.22Å; A681-Q684 PolarHBondContact O-N 3.44Å; Q684-R686 PolarHBondContact O-N 3.36Å; Q684-G687 PolarHBondContact O-N 3.22Å; Q684-G687 VanDerWaalsContact O-N 3.08Å; Q684-I691 HydrophobicContact CG-CD1 4.3Å
685E97.3Very high94.5Very high157 Ų15747 Ų4773%0.73427%0.266SS*.THydrogen-bonded Turntrans-59.5-18.4174.3-75.1174.6-177.700113.5A681A681-E685 WeakPolarHBondContact O-CB 3.42Å; A681-E685 VanDerWaalsContact O-CG 3.27Å; A681-E685 WeakPolarHBondContact O-CG 3.3Å; A681-E685 PolarHBondContact O-N 3.21Å
686R96.9Very high94.6Very high104 Ų10449.1 Ų49.139%0.39228%0.28SS..THydrogen-bonded Turntrans-106.618179.7-72.4172.5175.468.23.7113.4P653 V656 F682 L683 Q684P653-R686 HydrophobicContact CG-CB 4.5Å; V656-R686 WeakPolarHBondContact CG1-O 3.38Å; F682-R686 VanDerWaalsContact CZ-CZ 3.44Å; F682-R686 PolarHBondContact O-NH1 3.03Å; F682-R686 VanDerWaalsContact O-NH1 3.1Å; L683-R686 CarbonylContact O-C 3.59Å; L683-R686 PolarHBondContact O-N 3.09Å; Q684-R686 PolarHBondContact O-N 3.36Å
687G96Very high94.9Very high45 Ų4550.4 Ų50.446%0.46429%0.288SS..THydrogen-bonded Turntrans95.310.9169.800000115.6L683 Q684 A689L683-G687 PolarHBondContact O-N 3.44Å; Q684-G687 PolarHBondContact O-N 3.22Å; Q684-G687 VanDerWaalsContact O-N 3.08Å; G687-A689 PolarHBondContact O-N 3.18Å
688V97.6Very high95.2Very high6 Ų647.4 Ų47.44%0.03627%0.268CS..EExtended strand (participates in β ladder)trans-77.4119.7170.1-179.90000109.6I652 V669 A671 L683 A690 I691I652-V688 HydrophobicContact CG2-CG2 3.44Å; I652-V688 VanDerWaalsContact CG2-CG2 3.44Å; V669-V688 CarbonylContact O-C 3.55Å; V669-V688 WeakPolarHBondContact O-CA 3.41Å; A671-V688 HydrophobicContact CB-CG1 3.91Å; L683-V688 HydrophobicContact CB-CB 4.2Å; L683-V688 HydrophobicContact CB-CG2 3.98Å; L683-V688 WeakPolarHBondContact O-CB 3.38Å; L683-V688 WeakPolarHBondContact O-CG2 3.27Å; L683-V688 PolarHBondContact O-N 3.3Å; V688-A690 VanDerWaalsContact CG1-O 3.31Å; V688-A690 WeakPolarHBondContact CG1-O 3.41Å; V688-I691 HydrophobicContact CG1-CG1 3.92Å
689A96.9Very high95.5Very high46 Ų4642.1 Ų42.138%0.3824%0.244SC..EExtended strand (participates in β ladder)trans-76.1-35.8-174.200000113.4C668 V669 V670 G687 L708C668-A689 WeakPolarHBondContact SG-CB 3.49Å; V669-A689 PolarHBondContact O-N 2.72Å; V670-A689 HydrophobicContact CG1-CB 4.39Å; G687-A689 PolarHBondContact O-N 3.18Å; A689-L708 HydrophobicContact CB-CD1 4.48Å
690A97.1Very high95.7Very high10 Ų1044.9 Ų44.98%0.08326%0.258CS..EExtended strand (participates in β ladder)trans-153.1155178.200000111.6V670 A671 V688 Y692 L708V670-A690 WeakPolarHBondContact CA-O 3.48Å; V670-A690 HydrophobicContact CG1-CB 4.05Å; A671-A690 PolarHBondContact N-O 2.85Å; V688-A690 VanDerWaalsContact CG1-O 3.31Å; V688-A690 WeakPolarHBondContact CG1-O 3.41Å; A690-Y692 HydrophobicContact CB-CE1 4.4Å; A690-Y692 HydrophobicContact CB-CE2 4.02Å; A690-Y692 WeakPolarHBondContact CB-OH 3.43Å; A690-L708 HydrophobicContact CB-CD1 3.75Å
691I97.4Very high95.8Very high23 Ų2342.5 Ų42.512%0.11825%0.25CC..EExtended strand (participates in β ladder)trans-129.3127.7-178.9-55.9172.6000109.1A671 I675 Y680 L683 Q684 V688A671-I691 HydrophobicContact CB-CG1 4.37Å; A671-I691 CarbonylContact O-C 3.46Å; A671-I691 VanDerWaalsContact O-CA 3.3Å; A671-I691 WeakPolarHBondContact O-CA 3.46Å; I675-I691 HydrophobicContact CB-CG2 4.49Å; I675-I691 HydrophobicContact CD1-CG2 4.01Å; Y680-I691 HydrophobicContact CD1-CD1 3.89Å; Y680-I691 HydrophobicContact CD1-CG2 4.08Å; Y680-I691 HydrophobicContact CD2-CB 4.19Å; Y680-I691 HydrophobicContact CD2-CD1 4.01Å; Y680-I691 HydrophobicContact CD2-CG2 4.28Å; Y680-I691 HydrophobicContact CE1-CG2 3.63Å; Y680-I691 HydrophobicContact CE2-CB 4.03Å; Y680-I691 HydrophobicContact CE2-CG2 3.84Å; Y680-I691 HydrophobicContact CG-CD1 3.61Å; Y680-I691 HydrophobicContact CG-CG2 4.4Å; L683-I691 HydrophobicContact CB-CD1 4.05Å; L683-I691 HydrophobicContact CD1-CD1 4.11Å; Q684-I691 HydrophobicContact CG-CD1 4.3Å; V688-I691 HydrophobicContact CG1-CG1 3.92Å
692Y96.3Very high95.8Very high35 Ų3540 Ų4014%0.13723%0.229CC..EExtended strand (participates in β ladder)trans-11993-177.4-55-68000110.6V670 A671 G672 G673 A690 T696 D704 V705V670-Y692 HydrophobicContact CB-CE2 3.97Å; V670-Y692 HydrophobicContact CG1-CE2 4.32Å; V670-Y692 HydrophobicContact CG2-CE2 4.16Å; A671-Y692 PolarHBondContact O-N 3.2Å; G672-Y692 WeakPolarHBondContact CA-O 3.43Å; G673-Y692 PolarHBondContact N-O 3.11Å; A690-Y692 HydrophobicContact CB-CE1 4.4Å; A690-Y692 HydrophobicContact CB-CE2 4.02Å; A690-Y692 WeakPolarHBondContact CB-OH 3.43Å; Y692-T696 HydrophobicContact CD1-CG2 3.87Å; Y692-T696 HydrophobicContact CG-CG2 4.39Å; Y692-D704 HydrophobicContact CE1-CB 4.3Å; Y692-D704 VanDerWaalsContact CE1-OD2 3.32Å; Y692-D704 WeakPolarHBondContact CE1-OD2 3.5Å; Y692-D704 VanDerWaalsContact OH-CG 3.32Å; Y692-D704 PolarHBondContact OH-OD2 3.28Å; Y692-V705 HydrophobicContact CE2-CG2 3.74Å; Y692-V705 WeakPolarHBondContact OH-CG2 3.35Å
693G92Very high95.8Very high10 Ų1040.8 Ų40.810%0.10323%0.23CC..  trans-75.8175.3178.800000114.4G695 T696G693-G695 PolarHBondContact O-N 3.43Å; G693-T696 PolarHBondContact N-OG1 2.91Å; G693-T696 WeakPolarHBondContact O-CB 3.16Å; G693-T696 PolarHBondContact O-N 2.9Å; G693-T696 PolarHBondContact O-OG1 3.43Å
694P92.2Very high95.7Very high37 Ų3743.9 Ų43.924%0.2425%0.247CC..THydrogen-bonded Turntrans-46.5134.5171.7-28.732.1000113.4E327 Q328 G673 V674 T696E327-P694 HydrophobicContact CB-CB 4.13Å; E327-P694 HydrophobicContact CB-CG 4.41Å; E327-P694 WeakPolarHBondContact OE2-CD 3.47Å; Q328-P694 PolarHBondContact NE2-O 3.01Å; G673-P694 WeakPolarHBondContact O-CD 3.41Å; V674-P694 HydrophobicContact CG2-CG 4.46Å; P694-T696 VanDerWaalsContact C-N 3.34Å
695G92.3Very high95.7Very high38 Ų3839 Ų3939%0.39222%0.224SC..THydrogen-bonded Turntrans85.3-1.7179.100000115.4G693 P697G693-G695 PolarHBondContact O-N 3.43Å; G695-P697 WeakPolarHBondContact O-CD 3.41Å
696T94.4Very high95.7Very high48 Ų4831.6 Ų31.629%0.29419%0.19SC..  trans-58.5123.3169.8-59.80000110.5Y692 G693 P694 M698Y692-T696 HydrophobicContact CD1-CG2 3.87Å; Y692-T696 HydrophobicContact CG-CG2 4.39Å; G693-T696 PolarHBondContact N-OG1 2.91Å; G693-T696 WeakPolarHBondContact O-CB 3.16Å; G693-T696 PolarHBondContact O-N 2.9Å; G693-T696 PolarHBondContact O-OG1 3.43Å; P694-T696 VanDerWaalsContact C-N 3.34Å; T696-M698 PolarHBondContact O-N 3.28Å
697P95.6Very high95.6Very high40 Ų4030.2 Ų30.226%0.2619%0.19SC..  trans-63.9131.4173.7-20.533000111.1G695 L699 D700 S701G695-P697 WeakPolarHBondContact O-CD 3.41Å; P697-L699 PolarHBondContact O-N 3.34Å; P697-D700 HydrophobicContact CB-CB 4.17Å; P697-D700 PolarHBondContact O-N 3.32Å; P697-S701 PolarHBondContact O-N 3.42Å
698M95.4Very high95.5Very high2 Ų229.4 Ų29.41%0.0118%0.175CC..Hα-helixtrans-59.9-48.2-173.4-178.9173.67100112.4D447 I553 Y557 V603 I604 A607 T696 D700 S701 V702D447-M698 WeakPolarHBondContact OD2-CB 3.49Å; D447-M698 PolarHBondContact OD2-N 3.17Å; I553-M698 HydrophobicContact CB-CE 4.39Å; I553-M698 HydrophobicContact CD1-CE 3.77Å; I553-M698 HydrophobicContact CD1-SD 3.66Å; I553-M698 HydrophobicContact CG1-CE 4.07Å; I553-M698 HydrophobicContact CG2-CE 3.44Å; I553-M698 VanDerWaalsContact CG2-CE 3.44Å; Y557-M698 HydrophobicContact CE2-CE 4.05Å; V603-M698 HydrophobicContact CG1-SD 4.02Å; I604-M698 HydrophobicContact CD1-CB 4.33Å; I604-M698 HydrophobicContact CD1-CG 3.85Å; A607-M698 HydrophobicContact CB-CE 3.94Å; A607-M698 HydrophobicContact CB-CG 3.37Å; A607-M698 HydrophobicContact CB-SD 3.19Å; A607-M698 WeakPolarHBondContact CB-SD 3.27Å; T696-M698 PolarHBondContact O-N 3.28Å; M698-D700 VanDerWaalsContact C-N 3.28Å; M698-D700 PolarHBondContact O-N 3.03Å; M698-S701 PolarHBondContact O-N 3.06Å; M698-S701 PolarHBondContact O-OG 3.37Å; M698-V702 VanDerWaalsContact O-CG2 3.27Å; M698-V702 WeakPolarHBondContact O-CG2 3.4Å; M698-V702 PolarHBondContact O-N 3.23Å
699L95.2Very high95.3Very high3 Ų329.2 Ų29.22%0.01617%0.174CC..Hα-helixtrans-63.7-33.5179.3-65.3-164.5000112.8Y557 E566 F567 I570 L611 P697 R703Y557-L699 HydrophobicContact CD1-CD1 3.98Å; Y557-L699 HydrophobicContact CE1-CD1 3.37Å; Y557-L699 HydrophobicContact CE1-CG 4.09Å; E566-L699 HydrophobicContact CG-CD1 3.86Å; F567-L699 HydrophobicContact CD2-CD2 4.24Å; I570-L699 HydrophobicContact CD1-CB 3.74Å; I570-L699 HydrophobicContact CD1-CD1 4.35Å; I570-L699 HydrophobicContact CD1-CD2 4.16Å; I570-L699 HydrophobicContact CD1-CG 4.29Å; I570-L699 WeakPolarHBondContact CD1-O 3.18Å; L611-L699 HydrophobicContact CD1-CD2 3.6Å; L611-L699 HydrophobicContact CD2-CD2 4.18Å; L611-L699 HydrophobicContact CG-CD2 4.42Å; P697-L699 PolarHBondContact O-N 3.34Å; L699-R703 WeakPolarHBondContact O-CB 3.29Å; L699-R703 PolarHBondContact O-N 3.11Å
700D95.5Very high95Very high72 Ų7229.3 Ų29.339%0.38517%0.172SC..Hα-helixtrans-69.2-43.2176.6-70-26.4000110.8P697 M698 V702 R703 D704P697-D700 HydrophobicContact CB-CB 4.17Å; P697-D700 PolarHBondContact O-N 3.32Å; M698-D700 VanDerWaalsContact C-N 3.28Å; M698-D700 PolarHBondContact O-N 3.03Å; D700-V702 VanDerWaalsContact C-N 3.34Å; D700-V702 PolarHBondContact O-N 3.23Å; D700-R703 PolarHBondContact O-N 3.07Å; D700-R703 IonicContact OD1-CZ 3.88Å; D700-R703 IonicContact OD1-NH1 3.67Å; D700-R703 PolarHBondContact OD1-NH1 3.08Å; D700-D704 WeakPolarHBondContact O-CB 3.48Å; D700-D704 PolarHBondContact O-N 3.09Å
701S96.5Very high94.1Very high6 Ų635.6 Ų35.64%0.04220%0.199CC..Hα-helixtrans-61.4-40.2175.274.30000112.6P697 M698 D704 V705P697-S701 PolarHBondContact O-N 3.42Å; M698-S701 PolarHBondContact O-N 3.06Å; M698-S701 PolarHBondContact O-OG 3.37Å; S701-D704 PolarHBondContact O-N 3.02Å; S701-V705 WeakPolarHBondContact O-CG2 3.38Å; S701-V705 PolarHBondContact O-N 2.93Å
702V96.7Very high92.5Very high0 Ų039.8 Ų39.80%022%0.218CC..Hα-helixtrans-64.7-45177.9177.10000110.5I570 Y608 L611 F613 M698 D700 D704 V705 L706I570-V702 HydrophobicContact CG2-CG1 3.98Å; Y608-V702 HydrophobicContact CD2-CG2 3.6Å; Y608-V702 HydrophobicContact CE1-CG1 4.46Å; Y608-V702 HydrophobicContact CE2-CB 4.27Å; Y608-V702 HydrophobicContact CE2-CG2 3.36Å; Y608-V702 HydrophobicContact CG-CG2 4.29Å; L611-V702 HydrophobicContact CB-CG1 4.45Å; L611-V702 HydrophobicContact CD1-CB 3.95Å; L611-V702 HydrophobicContact CD1-CG1 3.7Å; L611-V702 HydrophobicContact CD1-CG2 3.67Å; F613-V702 HydrophobicContact CD2-CG1 4.41Å; F613-V702 HydrophobicContact CE2-CG1 3.59Å; F613-V702 HydrophobicContact CZ-CG1 4.11Å; M698-V702 VanDerWaalsContact O-CG2 3.27Å; M698-V702 WeakPolarHBondContact O-CG2 3.4Å; M698-V702 PolarHBondContact O-N 3.23Å; D700-V702 VanDerWaalsContact C-N 3.34Å; D700-V702 PolarHBondContact O-N 3.23Å; V702-D704 VanDerWaalsContact C-N 3.35Å; V702-V705 PolarHBondContact O-N 3.26Å; V702-L706 WeakPolarHBondContact O-CB 3.23Å; V702-L706 PolarHBondContact O-N 3.01Å
703R95.8Very high90.6Very high71 Ų7141.4 Ų41.427%0.26823%0.227SC..Hα-helixtrans-63-42.6178.8-169.5-173.1-60.2125.81.2111.4E566 I570 L699 D700 L706 N707E566-R703 IonicContact OE1-NH2 2.81Å; I570-R703 HydrophobicContact CD1-CB 4.41Å; L699-R703 WeakPolarHBondContact O-CB 3.29Å; L699-R703 PolarHBondContact O-N 3.11Å; D700-R703 PolarHBondContact O-N 3.07Å; D700-R703 IonicContact OD1-CZ 3.88Å; D700-R703 IonicContact OD1-NH1 3.67Å; D700-R703 PolarHBondContact OD1-NH1 3.08Å; R703-L706 PolarHBondContact O-N 3.36Å; R703-N707 VanDerWaalsContact O-CG 3.24Å; R703-N707 PolarHBondContact O-N 3.07Å; R703-N707 PolarHBondContact O-ND2 3.06Å
704D96.3Very high88Confident65 Ų6550.9 Ų50.935%0.34828%0.275SS..Hα-helixtrans-63.6-48.2177.9-172.236.7000111.7Y692 D700 S701 V702 L706 N707 L708Y692-D704 HydrophobicContact CE1-CB 4.3Å; Y692-D704 VanDerWaalsContact CE1-OD2 3.32Å; Y692-D704 WeakPolarHBondContact CE1-OD2 3.5Å; Y692-D704 VanDerWaalsContact OH-CG 3.32Å; Y692-D704 PolarHBondContact OH-OD2 3.28Å; D700-D704 WeakPolarHBondContact O-CB 3.48Å; D700-D704 PolarHBondContact O-N 3.09Å; S701-D704 PolarHBondContact O-N 3.02Å; V702-D704 VanDerWaalsContact C-N 3.35Å; D704-L706 VanDerWaalsContact C-N 3.34Å; D704-L706 PolarHBondContact O-N 2.78Å; D704-N707 WeakPolarHBondContact O-CB 3.28Å; D704-N707 PolarHBondContact O-N 3.24Å; D704-N707 VanDerWaalsContact O-N 3.14Å; D704-L708 WeakPolarHBondContact O-CG 3.49Å; D704-L708 PolarHBondContact O-N 3.37Å
705V97.2Very high87.8Confident0 Ų051.6 Ų51.60%028%0.277CS..Hα-helixtrans-60.1-41.8174.9170.30000112.1Y608 V638 V670 Y692 S701 V702 N707 L708 I709Y608-V705 HydrophobicContact CE1-CB 4.46Å; Y608-V705 HydrophobicContact CE1-CG1 4.15Å; Y608-V705 VanDerWaalsContact OH-CB 3.31Å; Y608-V705 WeakPolarHBondContact OH-CB 3.27Å; Y608-V705 WeakPolarHBondContact OH-CG2 3.38Å; V638-V705 HydrophobicContact CG1-CG1 3.88Å; V638-V705 HydrophobicContact CG2-CG1 4.25Å; V670-V705 HydrophobicContact CG1-CG2 4.35Å; V670-V705 HydrophobicContact CG2-CG2 4.27Å; Y692-V705 HydrophobicContact CE2-CG2 3.74Å; Y692-V705 WeakPolarHBondContact OH-CG2 3.35Å; S701-V705 WeakPolarHBondContact O-CG2 3.38Å; S701-V705 PolarHBondContact O-N 2.93Å; V702-V705 PolarHBondContact O-N 3.26Å; V705-N707 VanDerWaalsContact C-N 3.3Å; V705-N707 PolarHBondContact O-N 3.47Å; V705-L708 PolarHBondContact O-N 3.35Å; V705-I709 WeakPolarHBondContact O-CG1 3.49Å; V705-I709 PolarHBondContact O-N 3.44Å
706L96.4Very high87.6Confident3 Ų352.3 Ų52.32%0.01627%0.271CS..Hα-helixtrans-60.5-40.3176.6-173.459.3000111.7Q573 T574 F577 P585 F613 V702 R703 D704 I709 S710Q573-L706 HydrophobicContact CB-CD2 3.48Å; Q573-L706 VanDerWaalsContact CB-CD2 3.48Å; T574-L706 HydrophobicContact CG2-CD1 4.38Å; T574-L706 HydrophobicContact CG2-CD2 3.85Å; F577-L706 HydrophobicContact CB-CD1 4.32Å; F577-L706 HydrophobicContact CD2-CD1 4.03Å; F577-L706 HydrophobicContact CG-CD1 4.3Å; P585-L706 HydrophobicContact CB-CD1 4.14Å; P585-L706 HydrophobicContact CG-CD1 4.11Å; F613-L706 HydrophobicContact CZ-CB 4.17Å; F613-L706 HydrophobicContact CZ-CD1 4.04Å; V702-L706 WeakPolarHBondContact O-CB 3.23Å; V702-L706 PolarHBondContact O-N 3.01Å; R703-L706 PolarHBondContact O-N 3.36Å; D704-L706 VanDerWaalsContact C-N 3.34Å; D704-L706 PolarHBondContact O-N 2.78Å; L706-I709 HydrophobicContact CD1-CD1 4.22Å; L706-I709 HydrophobicContact CD1-CG1 4.49Å; L706-I709 WeakPolarHBondContact O-CG1 3.49Å; L706-S710 WeakPolarHBondContact O-CB 3.08Å; L706-S710 PolarHBondContact O-N 3.2Å; L706-S710 VanDerWaalsContact O-N 3.09Å; L706-S710 PolarHBondContact O-OG 3.43Å
707N94.9Very high87.2Confident75 Ų7552.5 Ų52.540%0.40127%0.269SS..Hα-helixtrans-66.4-43.6175.2-68.7-31.1000111.9R703 D704 V705 I709 S710 Q711R703-N707 VanDerWaalsContact O-CG 3.24Å; R703-N707 PolarHBondContact O-N 3.07Å; R703-N707 PolarHBondContact O-ND2 3.06Å; D704-N707 WeakPolarHBondContact O-CB 3.28Å; D704-N707 PolarHBondContact O-N 3.24Å; D704-N707 VanDerWaalsContact O-N 3.14Å; V705-N707 VanDerWaalsContact C-N 3.3Å; V705-N707 PolarHBondContact O-N 3.47Å; N707-I709 PolarHBondContact O-N 3.29Å; N707-S710 PolarHBondContact O-N 3.27Å; N707-Q711 WeakPolarHBondContact O-CG 3.11Å; N707-Q711 PolarHBondContact O-N 2.87Å; N707-Q711 VanDerWaalsContact O-N 3.15Å
708L94.2Very high86.7Confident28 Ų2853.2 Ų53.215%0.14727%0.27CS..Hα-helixtrans-58.6-47.9179-73.2169.8000111.7V670 A689 A690 D704 V705 Q711 H712V670-L708 HydrophobicContact CG1-CD1 4.22Å; A689-L708 HydrophobicContact CB-CD1 4.48Å; A690-L708 HydrophobicContact CB-CD1 3.75Å; D704-L708 WeakPolarHBondContact O-CG 3.49Å; D704-L708 PolarHBondContact O-N 3.37Å; V705-L708 PolarHBondContact O-N 3.35Å; L708-Q711 PolarHBondContact O-N 2.58Å; L708-H712 PolarHBondContact O-ND1 3.01Å
709I94.3Very high86.2Confident1 Ų156.4 Ų56.41%0.00529%0.286CS..Hα-helixtrans-72.4-29.7-18065.7179.8000112.3F577 P585 F613 H637 V638 C668 V705 L706 N707 Q711 H712 H713F577-I709 HydrophobicContact CE2-CD1 4.08Å; F577-I709 HydrophobicContact CE2-CG1 4.02Å; F577-I709 HydrophobicContact CZ-CD1 4.25Å; P585-I709 HydrophobicContact CB-CD1 3.56Å; F613-I709 HydrophobicContact CE1-CD1 4.29Å; H637-I709 HydrophobicContact CB-CB 4.33Å; H637-I709 HydrophobicContact CB-CD1 4.29Å; H637-I709 HydrophobicContact CB-CG2 4.14Å; V638-I709 HydrophobicContact CB-CG2 3.87Å; V638-I709 HydrophobicContact CG1-CG2 4.08Å; C668-I709 HydrophobicContact CB-CG2 4.43Å; V705-I709 WeakPolarHBondContact O-CG1 3.49Å; V705-I709 PolarHBondContact O-N 3.44Å; L706-I709 HydrophobicContact CD1-CD1 4.22Å; L706-I709 HydrophobicContact CD1-CG1 4.49Å; L706-I709 WeakPolarHBondContact O-CG1 3.49Å; N707-I709 PolarHBondContact O-N 3.29Å; I709-Q711 VanDerWaalsContact C-N 3.28Å; I709-Q711 PolarHBondContact O-N 3.13Å; I709-H712 PolarHBondContact O-N 3.11Å; I709-H713 PolarHBondContact O-CD2 2.72Å; I709-H713 VanDerWaalsContact O-CD2 3.23Å
710S88.8Confident85.6Confident49 Ų4960 Ų6034%0.34330%0.304SS..Hα-helixtrans-68.8-28176.5-57.90000112.4L706 N707L706-S710 WeakPolarHBondContact O-CB 3.08Å; L706-S710 PolarHBondContact O-N 3.2Å; L706-S710 VanDerWaalsContact O-N 3.09Å; L706-S710 PolarHBondContact O-OG 3.43Å; N707-S710 PolarHBondContact O-N 3.27Å
711Q78.3Confident84.9Confident141 Ų14159.1 Ų59.166%0.65930%0.298SS*.Hα-helixtrans-79.9-18.5177.6-70.7174.210.900114.2N707 L708 I709N707-Q711 WeakPolarHBondContact O-CG 3.11Å; N707-Q711 PolarHBondContact O-N 2.87Å; N707-Q711 VanDerWaalsContact O-N 3.15Å; L708-Q711 PolarHBondContact O-N 2.58Å; I709-Q711 VanDerWaalsContact C-N 3.28Å; I709-Q711 PolarHBondContact O-N 3.13Å
712H65.4Low84Confident111 Ų11163.2 Ų63.251%0.51432%0.318SS..SBendtrans-98.3-3.9-175.1-75.376.7000113.9L708 I709L708-H712 PolarHBondContact O-ND1 3.01Å; I709-H712 PolarHBondContact O-N 3.11Å
713H55.4Low82.9Confident69 Ų6968.5 Ų68.532%0.31935%0.345SS..  trans-111.27.5-177.9-75.5-60.2000114.9H637 I709H637-H713 AromaticContact CD2-CD2 3.75Å; H637-H713 AromaticContact CD2-NE2 3.37Å; H637-H713 PolarHBondContact CD2-NE2 3.47Å; I709-H713 PolarHBondContact O-CD2 2.72Å; I709-H713 VanDerWaalsContact O-CD2 3.23Å
714D38.1Very low81.7Confident209 Ų20968.3 Ų68.3100%1.11835%0.352SS*.  trans-90.20160.1-73.3-24.5000110.4

Retrieved 714 of 714 residues in 4374.1 ms (Link to these results)