A0A077ZNM1_TRITR Loading...

Integral membrane protein

AlphaFold DB , UniProt , Accession A0A077ZNM1, Species TRITR (Trichuris trichiura, Whipworm), Gene n/a, Length 566 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M32.1Very low32.8Very low242 Ų242108.6 Ų108.6100%1.19263%0.628SS**  066.10-173.7166.4166.300107.5
2K24.1Very low35.3Very low194 Ų194100.6 Ų100.684%0.84358%0.583SS**  54113.6102.6-82.1-173.9178177.80113.7
3L27.1Very low37.5Very low136 Ų13695.9 Ų95.971%0.71255%0.553SS**  trans84.485.5157-69.9144.6000118.6
4L27.9Very low39.5Very low148 Ų14889.9 Ų89.978%0.77552%0.519SS*.  trans-132.867.5143.1-82.8174.7000110.9
5V26.6Very low41.1Very low113 Ų11386.9 Ų86.969%0.68550%0.499SS*.  trans-74.9118.8165.2172.80000109.1
6G26.4Very low42.8Very low67 Ų6785.2 Ų85.269%0.69149%0.487SS*.  trans79.774.6152.400000117.5S8G6-S8 PolarHBondContact O-N 3.31Å
7V28.4Very low44.5Very low111 Ų11183.2 Ų83.267%0.67347%0.474SS*.  trans-90.980.9162.2-173.90000109.2S9V7-S9 PolarHBondContact O-N 2.96Å
8S29.4Very low46.4Very low75 Ų7582.2 Ų82.252%0.52447%0.473SS..  trans-76.8111164.2-1620000107.8G6 A10G6-S8 PolarHBondContact O-N 3.31Å; S8-A10 PolarHBondContact O-N 3.49Å
9S39.9Very low48.1Very low74 Ų7483.9 Ų83.952%0.51748%0.481SS..  trans-62.4114.8-179.9-167.10000109.9V7 G11V7-S9 PolarHBondContact O-N 2.96Å; S9-G11 PolarHBondContact O-N 3.49Å
10A45.9Very low49.8Very low33 Ų3388 Ų8827%0.27349%0.493SS..  trans-69.5111.4173.300000108.6S8S8-A10 PolarHBondContact O-N 3.49Å
11G53.1Low51.5Low2 Ų290.3 Ų90.32%0.02150%0.498CS..  trans-59.3153.4176.400000111.9S9 E15 S519S9-G11 PolarHBondContact O-N 3.49Å; G11-E15 WeakPolarHBondContact CA-OE2 3.35Å; G11-S519 WeakPolarHBondContact O-CA 3.35Å; G11-S519 WeakPolarHBondContact O-CB 3.14Å; G11-S519 PolarHBondContact O-N 3.11Å
12S62.2Low53.7Low12 Ų1279.6 Ų79.68%0.08445%0.445CS..BIsolated β-bridgetrans-70.3166.1171.7107.60000111.4V14 E15 N16 R451 M515 A517S12-V14 PolarHBondContact O-N 2.62Å; S12-V14 PolarHBondContact OG-N 3.02Å; S12-E15 WeakPolarHBondContact O-CB 3.49Å; S12-E15 PolarHBondContact O-N 3.36Å; S12-N16 PolarHBondContact O-ND2 3.15Å; S12-R451 VanDerWaalsContact CB-CZ 3.5Å; S12-R451 PolarHBondContact OG-NE 2.82Å; S12-R451 PolarHBondContact OG-NH2 2.69Å; S12-M515 PolarHBondContact OG-O 3.5Å; S12-A517 WeakPolarHBondContact CA-O 3.43Å; S12-A517 WeakPolarHBondContact CB-O 3.47Å
13I65Low56.4Low40 Ų4075.6 Ų75.621%0.20543%0.43CS..Hα-helixtrans-54.1-35.2176.9-70.6-179.2000112.4E15 N16 L17 W271 A517I13-E15 VanDerWaalsContact C-N 3.29Å; I13-E15 PolarHBondContact O-N 3.1Å; I13-N16 PolarHBondContact O-N 3.38Å; I13-L17 HydrophobicContact CG2-CD1 3.43Å; I13-L17 VanDerWaalsContact CG2-CD1 3.43Å; I13-L17 HydrophobicContact CG2-CG 3.98Å; I13-L17 PolarHBondContact O-N 3.41Å; I13-W271 HydrophobicContact CD1-CH2 3.72Å; I13-W271 HydrophobicContact CD1-CZ2 4.01Å; I13-A517 HydrophobicContact CD1-CB 3.9Å; I13-A517 HydrophobicContact CG1-CB 4.43Å; I13-A517 PolarHBondContact N-O 3.14Å
14V65Low59.3Low12 Ų1274.3 Ų74.37%0.07342%0.423CS..Hα-helixtrans-62.5-32.5176.7174.90000113.4S12 N16 Y450 R451 M515S12-V14 PolarHBondContact O-N 2.62Å; S12-V14 PolarHBondContact OG-N 3.02Å; V14-N16 PolarHBondContact O-N 3.39Å; V14-Y450 HydrophobicContact CG1-CD1 4.19Å; V14-Y450 HydrophobicContact CG1-CE1 4.31Å; V14-R451 HydrophobicContact CB-CG 4.23Å; V14-R451 HydrophobicContact CG1-CG 3.7Å; V14-M515 HydrophobicContact CB-CE 4.43Å; V14-M515 HydrophobicContact CG1-CE 4.17Å; V14-M515 HydrophobicContact CG2-CB 3.33Å; V14-M515 HydrophobicContact CG2-CE 3.32Å; V14-M515 HydrophobicContact CG2-CG 3.59Å; V14-M515 VanDerWaalsContact CG2-O 3.26Å; V14-M515 WeakPolarHBondContact CG2-O 3.45Å; V14-M515 HydrophobicContact CG2-SD 4.24Å; V14-M515 PolarHBondContact N-O 3.36Å
15E63.5Low62Low45 Ų4570 Ų7021%0.2140%0.4CS..Hα-helixtrans-68.5-24.1177.4-98.4166.1-116.100111.7G11 S12 I13 A447 R451 Y523G11-E15 WeakPolarHBondContact CA-OE2 3.35Å; S12-E15 WeakPolarHBondContact O-CB 3.49Å; S12-E15 PolarHBondContact O-N 3.36Å; I13-E15 VanDerWaalsContact C-N 3.29Å; I13-E15 PolarHBondContact O-N 3.1Å; E15-A447 HydrophobicContact CG-CB 3.41Å; E15-A447 VanDerWaalsContact CG-CB 3.41Å; E15-R451 IonicContact OE1-CZ 3.07Å; E15-R451 IonicContact OE1-NH1 2.74Å; E15-R451 PolarHBondContact OE1-NH1 2.78Å; E15-R451 IonicContact OE1-NH2 2.65Å; E15-R451 PolarHBondContact OE1-NH2 3.14Å; E15-Y523 PolarHBondContact OE2-OH 3.34Å
16N68.7Low64.6Low59 Ų5966.8 Ų66.832%0.31638%0.377SS..Hα-helixtrans-109.6-5.1-170.3-74.2-65.8000113.7S12 I13 V14 S519 K521S12-N16 PolarHBondContact O-ND2 3.15Å; I13-N16 PolarHBondContact O-N 3.38Å; V14-N16 PolarHBondContact O-N 3.39Å; N16-S519 VanDerWaalsContact ND2-CB 3.32Å; N16-S519 WeakPolarHBondContact ND2-CB 3.4Å; N16-S519 PolarHBondContact ND2-OG 3.31Å; N16-K521 HydrophobicContact CB-CD 4.27Å
17L71.5Confident67.5Low51 Ų5167.4 Ų67.427%0.26737%0.368SS..  trans-82.5126.5178.3-91.9160.1000109.9I13 K21I13-L17 HydrophobicContact CG2-CD1 3.43Å; I13-L17 VanDerWaalsContact CG2-CD1 3.43Å; I13-L17 HydrophobicContact CG2-CG 3.98Å; I13-L17 PolarHBondContact O-N 3.41Å; L17-K21 HydrophobicContact CD2-CB 3.4Å; L17-K21 HydrophobicContact CD2-CD 3.95Å; L17-K21 HydrophobicContact CD2-CG 4.32Å
18S78.8Confident70.5Confident66 Ų6665.5 Ų65.546%0.46236%0.358SS..  trans-64.2144.4167.5173.70000110.1K20 K21 M22S18-K20 PolarHBondContact O-N 2.91Å; S18-K20 PolarHBondContact OG-N 3.18Å; S18-K21 PolarHBondContact O-N 3.48Å; S18-M22 PolarHBondContact O-N 3.41Å; S18-M22 VanDerWaalsContact O-N 3.1Å
19N77.6Confident73.2Confident114 Ų11463.4 Ų63.461%0.6134%0.341SS*.Hα-helixtrans-47-36.7173.8-68.1-7000112.7M22 M23N19-M22 PolarHBondContact O-N 2.97Å; N19-M23 WeakPolarHBondContact O-CB 3.47Å; N19-M23 WeakPolarHBondContact O-CG 3.16Å; N19-M23 PolarHBondContact O-N 3.04Å
20K83.4Confident75.5Confident166 Ų16662.2 Ų62.272%0.72234%0.336SS*.Hα-helixtrans-61.4-47.8176.4-68.8-174.5178-176.70112.5S18 M22 M23 I24S18-K20 PolarHBondContact O-N 2.91Å; S18-K20 PolarHBondContact OG-N 3.18Å; K20-M22 VanDerWaalsContact C-N 3.31Å; K20-M22 PolarHBondContact O-N 3.04Å; K20-M23 PolarHBondContact O-N 3.13Å; K20-I24 VanDerWaalsContact O-CG1 3.28Å; K20-I24 WeakPolarHBondContact O-CG1 3.43Å; K20-I24 PolarHBondContact O-N 2.72Å
21K84.4Confident77.8Confident137 Ų13765.8 Ų65.860%0.59635%0.35SS*.Hα-helixtrans-66.5-37.5-179.4-67.6-172.1175.5-171.20111.5L17 S18 I24 L25L17-K21 HydrophobicContact CD2-CB 3.4Å; L17-K21 HydrophobicContact CD2-CD 3.95Å; L17-K21 HydrophobicContact CD2-CG 4.32Å; S18-K21 PolarHBondContact O-N 3.48Å; K21-I24 PolarHBondContact O-N 3Å; K21-L25 PolarHBondContact O-N 2.82Å
22M78.6Confident79.7Confident17 Ų1769.2 Ų69.28%0.08437%0.367CS..Hα-helixtrans-68-41.9176.9-179.1-168.275.200111.9S18 N19 K20 I24 L25 F26 Y450S18-M22 PolarHBondContact O-N 3.41Å; S18-M22 VanDerWaalsContact O-N 3.1Å; N19-M22 PolarHBondContact O-N 2.97Å; K20-M22 VanDerWaalsContact C-N 3.31Å; K20-M22 PolarHBondContact O-N 3.04Å; M22-I24 PolarHBondContact O-N 3.26Å; M22-L25 WeakPolarHBondContact O-CB 3.36Å; M22-L25 PolarHBondContact O-N 3.16Å; M22-F26 HydrophobicContact CE-CE2 3.98Å; M22-F26 HydrophobicContact CG-CD2 4.03Å; M22-F26 HydrophobicContact CG-CE2 3.27Å; M22-F26 HydrophobicContact CG-CZ 3.56Å; M22-F26 VanDerWaalsContact O-CD2 3.26Å; M22-F26 WeakPolarHBondContact O-CD2 2.84Å; M22-F26 WeakPolarHBondContact O-CG 3.44Å; M22-F26 PolarHBondContact O-N 3.42Å; M22-F26 HydrophobicContact SD-CE2 3.81Å; M22-F26 HydrophobicContact SD-CZ 4.16Å; M22-Y450 WeakPolarHBondContact CE-OH 3.45Å; M22-Y450 HydrophobicContact SD-CE1 3.87Å; M22-Y450 PolarHBondContact SD-OH 2.84Å
23M82.1Confident81.1Confident109 Ų10969.7 Ų69.754%0.53737%0.368SS..Hα-helixtrans-61.6-42.5172.9-75.1-57.8-60.700112.2N19 K20 L25 F26 V27N19-M23 WeakPolarHBondContact O-CB 3.47Å; N19-M23 WeakPolarHBondContact O-CG 3.16Å; N19-M23 PolarHBondContact O-N 3.04Å; K20-M23 PolarHBondContact O-N 3.13Å; M23-L25 VanDerWaalsContact C-N 3.32Å; M23-L25 PolarHBondContact O-N 3.31Å; M23-F26 PolarHBondContact O-N 3.03Å; M23-V27 WeakPolarHBondContact O-CG2 3.47Å; M23-V27 PolarHBondContact O-N 3.4Å
24I86.6Confident82.4Confident109 Ų10972.2 Ų72.256%0.55938%0.381SS*.Hα-helixtrans-58.9-46.4174.6-68.1163.6000110.3K20 K21 M22 F26 V27 C28K20-I24 VanDerWaalsContact O-CG1 3.28Å; K20-I24 WeakPolarHBondContact O-CG1 3.43Å; K20-I24 PolarHBondContact O-N 2.72Å; K21-I24 PolarHBondContact O-N 3Å; M22-I24 PolarHBondContact O-N 3.26Å; I24-F26 VanDerWaalsContact C-N 3.34Å; I24-F26 PolarHBondContact O-N 3.16Å; I24-V27 PolarHBondContact O-N 3.3Å; I24-C28 PolarHBondContact O-N 2.79Å; I24-C28 PolarHBondContact O-SG 3.15Å
25L84.9Confident83.8Confident58 Ų5873.5 Ų73.530%0.30439%0.393SS..Hα-helixtrans-56.5-47.3176.3-178.268.2000111.2K21 M22 M23 V27 C28 L29K21-L25 PolarHBondContact O-N 2.82Å; M22-L25 WeakPolarHBondContact O-CB 3.36Å; M22-L25 PolarHBondContact O-N 3.16Å; M23-L25 VanDerWaalsContact C-N 3.32Å; M23-L25 PolarHBondContact O-N 3.31Å; L25-V27 PolarHBondContact O-N 2.93Å; L25-C28 PolarHBondContact O-N 2.97Å; L25-L29 HydrophobicContact CD1-CG 4.42Å; L25-L29 HydrophobicContact CG-CD1 4.23Å; L25-L29 HydrophobicContact CG-CG 4.43Å; L25-L29 VanDerWaalsContact O-CG 3.31Å; L25-L29 WeakPolarHBondContact O-CG 3.12Å; L25-L29 PolarHBondContact O-N 2.62Å
26F81.8Confident85.2Confident46 Ų4672 Ų7220%0.20239%0.386CS..Hα-helixtrans-65.5-39.1179.4-64.4-39.7000113.7M22 M23 I24 C28 L29 A30 F454 M515M22-F26 HydrophobicContact CE-CE2 3.98Å; M22-F26 HydrophobicContact CG-CD2 4.03Å; M22-F26 HydrophobicContact CG-CE2 3.27Å; M22-F26 HydrophobicContact CG-CZ 3.56Å; M22-F26 VanDerWaalsContact O-CD2 3.26Å; M22-F26 WeakPolarHBondContact O-CD2 2.84Å; M22-F26 WeakPolarHBondContact O-CG 3.44Å; M22-F26 PolarHBondContact O-N 3.42Å; M22-F26 HydrophobicContact SD-CE2 3.81Å; M22-F26 HydrophobicContact SD-CZ 4.16Å; M23-F26 PolarHBondContact O-N 3.03Å; I24-F26 VanDerWaalsContact C-N 3.34Å; I24-F26 PolarHBondContact O-N 3.16Å; F26-C28 VanDerWaalsContact C-N 3.34Å; F26-L29 PolarHBondContact O-N 2.78Å; F26-A30 VanDerWaalsContact O-CB 3.29Å; F26-A30 WeakPolarHBondContact O-CB 3.44Å; F26-A30 PolarHBondContact O-N 2.98Å; F26-F454 HydrophobicContact CD1-CE2 4.33Å; F26-F454 HydrophobicContact CD1-CZ 4.27Å; F26-F454 HydrophobicContact CE1-CE1 4.21Å; F26-F454 AromaticContact CE1-CE2 3.36Å; F26-F454 HydrophobicContact CE1-CE2 3.36Å; F26-F454 AromaticContact CE1-CZ 3.16Å; F26-F454 HydrophobicContact CE1-CZ 3.16Å; F26-F454 HydrophobicContact CE2-CD2 4.16Å; F26-F454 AromaticContact CE2-CE2 3.56Å; F26-F454 HydrophobicContact CE2-CE2 3.56Å; F26-F454 HydrophobicContact CE2-CZ 4.22Å; F26-F454 AromaticContact CZ-CD2 3.71Å; F26-F454 HydrophobicContact CZ-CD2 3.71Å; F26-F454 HydrophobicContact CZ-CE1 4.11Å; F26-F454 AromaticContact CZ-CE2 2.9Å; F26-F454 HydrophobicContact CZ-CE2 2.9Å; F26-F454 AromaticContact CZ-CZ 3.16Å; F26-F454 HydrophobicContact CZ-CZ 3.16Å; F26-M515 HydrophobicContact CZ-CE 4.39Å
27V87.7Confident86.3Confident80 Ų8071.9 Ų71.949%0.48538%0.382SS..Hα-helixtrans-62.7-44.1174.31730000110.2M23 I24 L25 L29 A30 L31M23-V27 WeakPolarHBondContact O-CG2 3.47Å; M23-V27 PolarHBondContact O-N 3.4Å; I24-V27 PolarHBondContact O-N 3.3Å; L25-V27 PolarHBondContact O-N 2.93Å; V27-L29 PolarHBondContact O-N 3.3Å; V27-A30 PolarHBondContact O-N 2.89Å; V27-L31 HydrophobicContact CG1-CD1 4.14Å; V27-L31 HydrophobicContact CG1-CG 4.47Å; V27-L31 VanDerWaalsContact O-CG 3.32Å; V27-L31 WeakPolarHBondContact O-CG 3.48Å; V27-L31 PolarHBondContact O-N 3.21Å
28C89.9Confident87.3Confident71 Ų7173.5 Ų73.548%0.4839%0.391SS..Hα-helixtrans-61.2-44.5175.6-68.10000112.3I24 L25 F26 L31 L32I24-C28 PolarHBondContact O-N 2.79Å; I24-C28 PolarHBondContact O-SG 3.15Å; L25-C28 PolarHBondContact O-N 2.97Å; F26-C28 VanDerWaalsContact C-N 3.34Å; C28-L31 PolarHBondContact O-N 3.27Å; C28-L32 WeakPolarHBondContact O-CB 3.43Å; C28-L32 PolarHBondContact O-N 2.91Å
29L87.8Confident87.9Confident30 Ų3073.1 Ų73.116%0.15738%0.383CS..Hα-helixtrans-65.6-37.5177.4-68.2-176.6000112L25 F26 V27 L32 Q33 V507 C511L25-L29 HydrophobicContact CD1-CG 4.42Å; L25-L29 HydrophobicContact CG-CD1 4.23Å; L25-L29 HydrophobicContact CG-CG 4.43Å; L25-L29 VanDerWaalsContact O-CG 3.31Å; L25-L29 WeakPolarHBondContact O-CG 3.12Å; L25-L29 PolarHBondContact O-N 2.62Å; F26-L29 PolarHBondContact O-N 2.78Å; V27-L29 PolarHBondContact O-N 3.3Å; L29-L32 PolarHBondContact O-N 3.45Å; L29-Q33 WeakPolarHBondContact O-CB 3.23Å; L29-Q33 PolarHBondContact O-N 3.37Å; L29-V507 HydrophobicContact CB-CG1 3.98Å; L29-V507 HydrophobicContact CD1-CG1 4.13Å; L29-V507 HydrophobicContact CD2-CG1 3.83Å; L29-V507 HydrophobicContact CG-CG1 4.17Å; L29-C511 HydrophobicContact CD1-CB 3.98Å
30A88Confident88.4Confident50 Ų5067.7 Ų67.741%0.41335%0.354SS..Hα-helixtrans-66.6-42.5175.700000111.9F26 V27 L32 Q33 I34F26-A30 VanDerWaalsContact O-CB 3.29Å; F26-A30 WeakPolarHBondContact O-CB 3.44Å; F26-A30 PolarHBondContact O-N 2.98Å; V27-A30 PolarHBondContact O-N 2.89Å; A30-L32 VanDerWaalsContact C-N 3.34Å; A30-Q33 WeakPolarHBondContact O-CB 3.42Å; A30-Q33 PolarHBondContact O-N 3.34Å; A30-I34 VanDerWaalsContact O-CG1 3.29Å; A30-I34 WeakPolarHBondContact O-CG1 3.22Å; A30-I34 PolarHBondContact O-N 3.5Å
31L92.9Very high88.5Confident108 Ų10859.9 Ų59.957%0.56532%0.321SS*.Hα-helixtrans-63.1-41.3174.4-70.7173.8000111.7V27 C28 Q33 I34 A35V27-L31 HydrophobicContact CG1-CD1 4.14Å; V27-L31 HydrophobicContact CG1-CG 4.47Å; V27-L31 VanDerWaalsContact O-CG 3.32Å; V27-L31 WeakPolarHBondContact O-CG 3.48Å; V27-L31 PolarHBondContact O-N 3.21Å; C28-L31 PolarHBondContact O-N 3.27Å; L31-Q33 VanDerWaalsContact C-N 3.33Å; L31-I34 PolarHBondContact O-N 2.9Å; L31-A35 PolarHBondContact O-N 3.42Å
32L92.6Very high88.6Confident74 Ų7458.6 Ų58.639%0.38732%0.32SS..Hα-helixtrans-63.2-40.8174.6-17860.3000111.4C28 L29 A30 A35 F36 V507C28-L32 WeakPolarHBondContact O-CB 3.43Å; C28-L32 PolarHBondContact O-N 2.91Å; L29-L32 PolarHBondContact O-N 3.45Å; A30-L32 VanDerWaalsContact C-N 3.34Å; L32-A35 WeakPolarHBondContact O-CB 3.33Å; L32-A35 PolarHBondContact O-N 2.82Å; L32-F36 HydrophobicContact CD1-CE1 4.5Å; L32-F36 HydrophobicContact CD1-CE2 3.96Å; L32-F36 HydrophobicContact CD1-CZ 3.82Å; L32-F36 HydrophobicContact CD2-CE2 4.2Å; L32-F36 HydrophobicContact CD2-CZ 4.43Å; L32-F36 HydrophobicContact CG-CD2 4.36Å; L32-F36 HydrophobicContact CG-CE2 3.63Å; L32-F36 HydrophobicContact CG-CZ 3.98Å; L32-F36 VanDerWaalsContact O-CD2 3.27Å; L32-F36 WeakPolarHBondContact O-CD2 3.39Å; L32-F36 PolarHBondContact O-N 3.33Å; L32-F36 VanDerWaalsContact O-N 3.1Å; L32-V507 HydrophobicContact CD2-CG2 3.78Å; L32-V507 HydrophobicContact CG-CG2 4.19Å
33Q92.6Very high89.1Confident22 Ų2265.1 Ų65.110%0.10335%0.348CS..Hα-helixtrans-62.1-44.2175.1-175.956.539.200112.3L29 A30 L31 A35 F36 F37 G500 M504L29-Q33 WeakPolarHBondContact O-CB 3.23Å; L29-Q33 PolarHBondContact O-N 3.37Å; A30-Q33 WeakPolarHBondContact O-CB 3.42Å; A30-Q33 PolarHBondContact O-N 3.34Å; L31-Q33 VanDerWaalsContact C-N 3.33Å; Q33-A35 VanDerWaalsContact C-N 3.28Å; Q33-A35 PolarHBondContact O-N 3.33Å; Q33-F36 PolarHBondContact O-N 3.48Å; Q33-F37 HydrophobicContact CG-CD2 4.19Å; Q33-F37 HydrophobicContact CG-CE2 3.85Å; Q33-F37 VanDerWaalsContact O-CD2 3.26Å; Q33-F37 WeakPolarHBondContact O-CD2 3.39Å; Q33-F37 PolarHBondContact O-N 2.99Å; Q33-G500 PolarHBondContact NE2-O 3.43Å; Q33-M504 VanDerWaalsContact OE1-N 3.16Å
34I92.3Very high89.4Confident93 Ų9360.1 Ų60.148%0.47732%0.324SS..Hα-helixtrans-60-42174.7-67.9164.6000110A30 L31 F36 F37 L38A30-I34 VanDerWaalsContact O-CG1 3.29Å; A30-I34 WeakPolarHBondContact O-CG1 3.22Å; A30-I34 PolarHBondContact O-N 3.5Å; L31-I34 PolarHBondContact O-N 2.9Å; I34-F36 VanDerWaalsContact C-N 3.31Å; I34-F36 PolarHBondContact O-N 3.28Å; I34-F37 PolarHBondContact O-N 3.41Å; I34-L38 HydrophobicContact CG2-CD1 3.93Å; I34-L38 HydrophobicContact CG2-CG 4.24Å; I34-L38 WeakPolarHBondContact O-CG 3.28Å; I34-L38 PolarHBondContact O-N 3.48Å
35A93.7Very high89.5Confident38 Ų3856.4 Ų56.431%0.31431%0.307SS..Hα-helixtrans-59.2-39.9176.400000112.4L31 L32 Q33 L38 I39L31-A35 PolarHBondContact O-N 3.42Å; L32-A35 WeakPolarHBondContact O-CB 3.33Å; L32-A35 PolarHBondContact O-N 2.82Å; Q33-A35 VanDerWaalsContact C-N 3.28Å; Q33-A35 PolarHBondContact O-N 3.33Å; A35-L38 PolarHBondContact O-N 3.29Å; A35-I39 VanDerWaalsContact O-CG1 3.24Å; A35-I39 WeakPolarHBondContact O-CG1 3.38Å; A35-I39 PolarHBondContact O-N 2.98Å
36F93.9Very high89.6Confident14 Ų1455.9 Ų55.96%0.06131%0.308CS..Hα-helixtrans-65-38.4176.1-67-50.3000113.7L32 Q33 I34 I39 G40 M257 L261 T499 V507L32-F36 HydrophobicContact CD1-CE1 4.5Å; L32-F36 HydrophobicContact CD1-CE2 3.96Å; L32-F36 HydrophobicContact CD1-CZ 3.82Å; L32-F36 HydrophobicContact CD2-CE2 4.2Å; L32-F36 HydrophobicContact CD2-CZ 4.43Å; L32-F36 HydrophobicContact CG-CD2 4.36Å; L32-F36 HydrophobicContact CG-CE2 3.63Å; L32-F36 HydrophobicContact CG-CZ 3.98Å; L32-F36 VanDerWaalsContact O-CD2 3.27Å; L32-F36 WeakPolarHBondContact O-CD2 3.39Å; L32-F36 PolarHBondContact O-N 3.33Å; L32-F36 VanDerWaalsContact O-N 3.1Å; Q33-F36 PolarHBondContact O-N 3.48Å; I34-F36 VanDerWaalsContact C-N 3.31Å; I34-F36 PolarHBondContact O-N 3.28Å; F36-I39 HydrophobicContact CD1-CD1 4.37Å; F36-I39 PolarHBondContact O-N 3.03Å; F36-G40 PolarHBondContact O-N 2.88Å; F36-M257 HydrophobicContact CB-CE 4.45Å; F36-M257 HydrophobicContact CD1-CE 3.39Å; F36-M257 HydrophobicContact CD1-SD 4.16Å; F36-M257 HydrophobicContact CE1-CE 3.7Å; F36-M257 HydrophobicContact CG-CE 3.94Å; F36-M257 HydrophobicContact CZ-CE 4.44Å; F36-L261 HydrophobicContact CE1-CD1 4.33Å; F36-L261 HydrophobicContact CE1-CD2 4.27Å; F36-L261 HydrophobicContact CZ-CD1 4.43Å; F36-L261 HydrophobicContact CZ-CD2 3.84Å; F36-T499 WeakPolarHBondContact O-CB 3.44Å; F36-T499 PolarHBondContact O-OG1 3.33Å; F36-V507 HydrophobicContact CE2-CG2 3.91Å
37F91.3Very high89.8Confident56 Ų5654.4 Ų54.425%0.24630%0.303CS..Hα-helixtrans-64-43.6172.3-76.9-69.7000111.5Q33 I34 I39 G40 G41 A496 F497Q33-F37 HydrophobicContact CG-CD2 4.19Å; Q33-F37 HydrophobicContact CG-CE2 3.85Å; Q33-F37 VanDerWaalsContact O-CD2 3.26Å; Q33-F37 WeakPolarHBondContact O-CD2 3.39Å; Q33-F37 PolarHBondContact O-N 2.99Å; I34-F37 PolarHBondContact O-N 3.41Å; F37-I39 PolarHBondContact O-N 3.34Å; F37-G40 PolarHBondContact O-N 3.07Å; F37-G41 PolarHBondContact O-N 3.36Å; F37-A496 VanDerWaalsContact CD1-O 3.26Å; F37-A496 WeakPolarHBondContact CD1-O 3.44Å; F37-F497 HydrophobicContact CE1-CD1 4.01Å; F37-F497 HydrophobicContact CE1-CE1 4.45Å
38L91.8Very high89.7Confident86 Ų8653.2 Ų53.245%0.4530%0.298SS..Hα-helixtrans-65.4-37.2178.4-68175.8000112.3I34 A35 G40 G41 L42I34-L38 HydrophobicContact CG2-CD1 3.93Å; I34-L38 HydrophobicContact CG2-CG 4.24Å; I34-L38 WeakPolarHBondContact O-CG 3.28Å; I34-L38 PolarHBondContact O-N 3.48Å; A35-L38 PolarHBondContact O-N 3.29Å; L38-G40 PolarHBondContact O-N 3.44Å; L38-G41 PolarHBondContact O-N 3.27Å; L38-L42 HydrophobicContact CB-CD1 4.26Å; L38-L42 HydrophobicContact CD2-CD1 4.08Å; L38-L42 VanDerWaalsContact O-CB 3.24Å; L38-L42 WeakPolarHBondContact O-CB 3.31Å; L38-L42 WeakPolarHBondContact O-CG 3.25Å; L38-L42 PolarHBondContact O-N 3.24Å
39I92Very high89.6Confident57 Ų5751 Ų5129%0.29229%0.285SS..Hα-helixtrans-59.3-47.7176.6-72.8163.8000110.7A35 F36 F37 F43 A44 V253A35-I39 VanDerWaalsContact O-CG1 3.24Å; A35-I39 WeakPolarHBondContact O-CG1 3.38Å; A35-I39 PolarHBondContact O-N 2.98Å; F36-I39 HydrophobicContact CD1-CD1 4.37Å; F36-I39 PolarHBondContact O-N 3.03Å; F37-I39 PolarHBondContact O-N 3.34Å; I39-F43 WeakPolarHBondContact O-CB 2.99Å; I39-F43 PolarHBondContact O-N 3.3Å; I39-F43 VanDerWaalsContact O-N 3.12Å; I39-A44 PolarHBondContact O-N 3.49Å; I39-V253 HydrophobicContact CG2-CG1 3.61Å
40G87.1Confident89.6Confident0 Ų053.3 Ų53.30%029%0.292CS..Hα-helixtrans-68.9-46.2177.500000112.5F36 F37 L38 L42 A44 S495 T499F36-G40 PolarHBondContact O-N 2.88Å; F37-G40 PolarHBondContact O-N 3.07Å; L38-G40 PolarHBondContact O-N 3.44Å; G40-L42 PolarHBondContact O-N 3Å; G40-A44 WeakPolarHBondContact O-CB 3.34Å; G40-A44 PolarHBondContact O-N 3.36Å; G40-A44 VanDerWaalsContact O-O 3.06Å; G40-S495 PolarHBondContact O-OG 2.9Å; G40-T499 WeakPolarHBondContact CA-OG1 3.5Å; G40-T499 PolarHBondContact N-OG1 3.14Å
41G86Confident89.7Confident3 Ų353 Ų533%0.03128%0.283CS..Hα-helixtrans-73-27.3-173.900000115.4F37 L38 Q492F37-G41 PolarHBondContact O-N 3.36Å; L38-G41 PolarHBondContact O-N 3.27Å; G41-Q492 PolarHBondContact O-N 3.13Å
42L87.5Confident89.6Confident110 Ų11051.4 Ų51.458%0.57628%0.275SS*.Hα-helixtrans-105.6-31.3-176.4-60.3177.1000114.1L38 G40 L491L38-L42 HydrophobicContact CB-CD1 4.26Å; L38-L42 HydrophobicContact CD2-CD1 4.08Å; L38-L42 VanDerWaalsContact O-CB 3.24Å; L38-L42 WeakPolarHBondContact O-CB 3.31Å; L38-L42 WeakPolarHBondContact O-CG 3.25Å; L38-L42 PolarHBondContact O-N 3.24Å; G40-L42 PolarHBondContact O-N 3Å; L42-L491 HydrophobicContact CD2-CD1 3.91Å
43F89Confident89.5Confident154 Ų15448 Ų4868%0.67526%0.257SS*.Hα-helixtrans-112.1-30.8-173.4-62.6-87000113.9I39I39-F43 WeakPolarHBondContact O-CB 2.99Å; I39-F43 PolarHBondContact O-N 3.3Å; I39-F43 VanDerWaalsContact O-N 3.12Å
44A88.1Confident89.6Confident3 Ų351.7 Ų51.73%0.02528%0.276CS..  trans-89.8129.3-178.100000110.2I39 G40 F250 V253 Q492 S495I39-A44 PolarHBondContact O-N 3.49Å; G40-A44 WeakPolarHBondContact O-CB 3.34Å; G40-A44 PolarHBondContact O-N 3.36Å; G40-A44 VanDerWaalsContact O-O 3.06Å; A44-F250 HydrophobicContact CB-CD2 3.95Å; A44-V253 HydrophobicContact CB-CB 3.92Å; A44-V253 HydrophobicContact CB-CG1 3.96Å; A44-V253 HydrophobicContact CB-CG2 3.99Å; A44-Q492 PolarHBondContact O-OE1 3.15Å; A44-S495 PolarHBondContact O-OG 3.25Å
45P88.6Confident89.7Confident31 Ų3147.6 Ų47.620%0.20126%0.255CS..  trans-69.1178169.435.3-38.6000111.1N247 G249 F250 Q492 S495P45-N247 WeakPolarHBondContact CB-ND2 3.27Å; P45-N247 HydrophobicContact CG-CB 4.32Å; P45-N247 WeakPolarHBondContact CG-OD1 3.29Å; P45-G249 VanDerWaalsContact CG-C 3.46Å; P45-F250 VanDerWaalsContact CD-N 3.35Å; P45-F250 HydrophobicContact CG-CB 4.21Å; P45-Q492 PolarHBondContact O-OE1 3.36Å; P45-S495 WeakPolarHBondContact O-CB 3.32Å
46S86.2Confident89.7Confident47 Ų4750.7 Ų50.733%0.32926%0.259SS..  trans-57.6140.4-175.257.20000108.7S48 N247S46-S48 WeakPolarHBondContact CB-O 3.43Å; S46-S48 PolarHBondContact O-N 3.08Å; S46-S48 PolarHBondContact OG-O 2.93Å; S46-N247 WeakPolarHBondContact O-CB 3.43Å
47P86.1Confident89.7Confident16 Ų1650.5 Ų50.510%0.10426%0.259CS..SBendtrans-57.5-38.7-174.2-26.736.3000112.9Q246 N247 F250 L498P47-Q246 WeakPolarHBondContact O-CA 3.36Å; P47-Q246 VanDerWaalsContact O-CG 3.28Å; P47-Q246 WeakPolarHBondContact O-CG 3.37Å; P47-N247 PolarHBondContact O-N 3.2Å; P47-F250 HydrophobicContact CB-CD1 4.2Å; P47-F250 HydrophobicContact CB-CD2 4.23Å; P47-F250 HydrophobicContact CB-CE1 4.14Å; P47-F250 HydrophobicContact CB-CE2 4.17Å; P47-F250 HydrophobicContact CB-CG 4.26Å; P47-F250 HydrophobicContact CB-CZ 4.13Å; P47-F250 HydrophobicContact CG-CD2 4.15Å; P47-F250 HydrophobicContact CG-CE2 3.97Å; P47-F250 HydrophobicContact CG-CZ 4.3Å; P47-L498 HydrophobicContact CB-CD1 3.66Å; P47-L498 HydrophobicContact CG-CD1 3.41Å; P47-L498 VanDerWaalsContact CG-CD1 3.41Å
48S87.1Confident89.8Confident54 Ų5447.9 Ų47.938%0.37825%0.247SC..EExtended strand (participates in β ladder)trans-116.7154.3173.550.90000111.1S46 H245S46-S48 WeakPolarHBondContact CB-O 3.43Å; S46-S48 PolarHBondContact O-N 3.08Å; S46-S48 PolarHBondContact OG-O 2.93Å; S48-H245 VanDerWaalsContact CA-O 3.31Å; S48-H245 WeakPolarHBondContact CA-O 3.48Å
49A86.4Confident89.8Confident25 Ų2544.1 Ų44.121%0.20723%0.228CC..EExtended strand (participates in β ladder)trans-130162.8164.900000107.9I244 H245A49-I244 WeakPolarHBondContact O-CA 3.36Å; A49-H245 PolarHBondContact N-O 3.38Å; A49-H245 PolarHBondContact O-N 2.96Å
50W88.3Confident89.8Confident78 Ų7841.4 Ų41.430%0.29521%0.214SC..EExtended strand (participates in β ladder)trans-144.7157.9-178.364.4-88.1000111.1N52 I242 E243 I244 L480 Y485W50-N52 HydrophobicContact CZ3-CB 4.01Å; W50-I242 HydrophobicContact CB-CG2 4.34Å; W50-I242 HydrophobicContact CE3-CG2 4.17Å; W50-E243 CarbonylContact C-O 3.42Å; W50-E243 WeakPolarHBondContact CA-O 3.46Å; W50-E243 VanDerWaalsContact CB-O 3.25Å; W50-E243 WeakPolarHBondContact CB-O 3.33Å; W50-I244 HydrophobicContact CB-CG1 3.99Å; W50-L480 HydrophobicContact CZ2-CD1 4.5Å; W50-L480 VanDerWaalsContact NE1-CD1 3.32Å; W50-Y485 AromaticContact CH2-CE1 3.79Å; W50-Y485 HydrophobicContact CH2-CE1 3.79Å; W50-Y485 AromaticContact CH2-CZ 3.68Å; W50-Y485 WeakPolarHBondContact CH2-OH 3.49Å; W50-Y485 AromaticContact CZ2-CE1 3.37Å; W50-Y485 HydrophobicContact CZ2-CE1 3.37Å; W50-Y485 AromaticContact CZ2-CZ 3.55Å; W50-Y485 WeakPolarHBondContact CZ2-OH 3.21Å
51M90Very high89.8Confident45 Ų4548.6 Ų48.622%0.22224%0.241CC..EExtended strand (participates in β ladder)trans-138.5136.1177.9-68.1-176.268.500109.2F53 P110 N111 L118 E243M51-F53 HydrophobicContact CB-CD2 4.37Å; M51-F53 HydrophobicContact CB-CE2 3.54Å; M51-F53 HydrophobicContact CB-CZ 3.93Å; M51-F53 HydrophobicContact CE-CZ 4.15Å; M51-F53 HydrophobicContact SD-CZ 4.41Å; M51-P110 HydrophobicContact CE-CB 4.37Å; M51-P110 HydrophobicContact SD-CB 4.33Å; M51-N111 HydrophobicContact CE-CB 3.93Å; M51-L118 HydrophobicContact CE-CD1 4.22Å; M51-E243 PolarHBondContact N-O 3.26Å; M51-E243 PolarHBondContact O-N 3.31Å
52N90.8Very high89.9Confident74 Ų7449.4 Ų49.440%0.39625%0.246SC..EExtended strand (participates in β ladder)trans-95.8137.8173.5-169.213.2000110.4W50 N111 I241W50-N52 HydrophobicContact CZ3-CB 4.01Å; N52-N111 PolarHBondContact O-ND2 3.39Å; N52-I241 CarbonylContact C-O 3.51Å; N52-I241 WeakPolarHBondContact CA-O 3.42Å; N52-I241 PolarHBondContact OD1-O 3.47Å
53F91.7Very high89.8Confident2 Ų246.5 Ų46.51%0.00923%0.231CC..EExtended strand (participates in β ladder)trans-126.3107.3-179.3-64.1-91.9000109.1M51 M55 M109 N111 N240 I241 E243M51-F53 HydrophobicContact CB-CD2 4.37Å; M51-F53 HydrophobicContact CB-CE2 3.54Å; M51-F53 HydrophobicContact CB-CZ 3.93Å; M51-F53 HydrophobicContact CE-CZ 4.15Å; M51-F53 HydrophobicContact SD-CZ 4.41Å; F53-M55 PolarHBondContact O-N 2.95Å; F53-M109 HydrophobicContact CD1-CG 3.95Å; F53-M109 HydrophobicContact CD2-CG 4.17Å; F53-M109 HydrophobicContact CD2-SD 4.45Å; F53-M109 HydrophobicContact CE1-CB 4.02Å; F53-M109 HydrophobicContact CE1-CG 3.69Å; F53-M109 HydrophobicContact CE2-CG 3.93Å; F53-M109 HydrophobicContact CE2-SD 4.31Å; F53-M109 HydrophobicContact CG-CG 4.19Å; F53-M109 HydrophobicContact CZ-CB 3.94Å; F53-M109 HydrophobicContact CZ-CG 3.7Å; F53-N111 HydrophobicContact CD1-CB 4.41Å; F53-N111 VanDerWaalsContact CD1-CG 3.41Å; F53-N111 VanDerWaalsContact CD1-ND2 3.28Å; F53-N111 WeakPolarHBondContact CD1-ND2 3.2Å; F53-N111 WeakPolarHBondContact CD1-OD1 3.37Å; F53-N111 HydrophobicContact CE1-CB 3.86Å; F53-N111 VanDerWaalsContact CE1-N 3.31Å; F53-N111 WeakPolarHBondContact CE1-OD1 3.41Å; F53-N240 CarbonylContact O-C 3.57Å; F53-N240 WeakPolarHBondContact O-CA 3.43Å; F53-I241 HydrophobicContact CB-CB 4.33Å; F53-I241 PolarHBondContact N-O 2.76Å; F53-I241 PolarHBondContact O-N 3.16Å; F53-E243 HydrophobicContact CD2-CB 4.07Å; F53-E243 HydrophobicContact CE2-CB 3.65Å; F53-E243 HydrophobicContact CE2-CG 4.39Å
54L93.1Very high89.4Confident99 Ų9940.2 Ų40.252%0.51821%0.21SC..EExtended strand (participates in β ladder)trans-68.7121.1162.9179.164.1000108.6E238 N240L54-E238 HydrophobicContact CD1-CB 4.15Å; L54-E238 HydrophobicContact CD1-CG 4.39Å; L54-E238 VanDerWaalsContact CD1-OE2 3.32Å; L54-E238 WeakPolarHBondContact CD1-OE2 3.45Å; L54-N240 VanDerWaalsContact CA-OD1 3.26Å; L54-N240 WeakPolarHBondContact CA-OD1 3.42Å; L54-N240 WeakPolarHBondContact CD1-OD1 3.28Å
55M94.1Very high89.2Confident7 Ų748.1 Ų48.13%0.03425%0.246CC..PPolyproline II helixtrans-73.2129.9179.3-60-167.479.600109.8F53 F105 V106 A107 L131 I218 L239 I241F53-M55 PolarHBondContact O-N 2.95Å; M55-F105 HydrophobicContact CB-CB 4.09Å; M55-F105 HydrophobicContact CB-CD1 4.44Å; M55-F105 VanDerWaalsContact CE-C 3.42Å; M55-F105 HydrophobicContact CE-CB 3.6Å; M55-F105 WeakPolarHBondContact CE-O 3.45Å; M55-F105 HydrophobicContact SD-CB 3.88Å; M55-V106 WeakPolarHBondContact CA-O 3.36Å; M55-A107 HydrophobicContact CE-CB 4.08Å; M55-A107 HydrophobicContact CG-CB 4.25Å; M55-L131 HydrophobicContact SD-CD1 4.22Å; M55-I218 HydrophobicContact CE-CB 4.12Å; M55-I218 HydrophobicContact CE-CD1 3.64Å; M55-I218 HydrophobicContact CE-CG1 3.73Å; M55-I218 HydrophobicContact SD-CD1 3.92Å; M55-L239 HydrophobicContact CB-CB 4.12Å; M55-L239 VanDerWaalsContact CB-O 3.29Å; M55-L239 WeakPolarHBondContact CB-O 3.46Å; M55-L239 HydrophobicContact CG-CB 3.98Å; M55-L239 VanDerWaalsContact CG-O 3.28Å; M55-L239 WeakPolarHBondContact CG-O 3.4Å; M55-L239 PolarHBondContact N-O 3.48Å; M55-L239 HydrophobicContact SD-CB 3.59Å; M55-L239 VanDerWaalsContact SD-CB 3.59Å; M55-L239 HydrophobicContact SD-CD1 4.02Å; M55-L239 HydrophobicContact SD-CG 4.48Å; M55-I241 HydrophobicContact CE-CD1 3.82Å; M55-I241 HydrophobicContact CG-CD1 4.04Å; M55-I241 HydrophobicContact CG-CG1 4.07Å; M55-I241 HydrophobicContact SD-CD1 3.57Å; M55-I241 VanDerWaalsContact SD-CD1 3.57Å; M55-I241 HydrophobicContact SD-CG1 3.9Å
56R94Very high89Confident104 Ų10452 Ų5239%0.39227%0.265SS..EExtended strand (participates in β ladder)trans-86146.5175.1-72.8169.2171.2-129.413.6110.3V72 E82 F105 V106R56-V72 HydrophobicContact CB-CG2 3.95Å; R56-V72 VanDerWaalsContact CD-CG1 3.48Å; R56-V72 HydrophobicContact CG-CG2 4.4Å; R56-E82 WeakPolarHBondContact CD-OE1 3.28Å; R56-E82 WeakPolarHBondContact CG-OE1 3.4Å; R56-E82 IonicContact CZ-OE1 3.34Å; R56-E82 IonicContact NE-OE1 3.62Å; R56-E82 IonicContact NH1-OE1 3.52Å; R56-E82 PolarHBondContact NH1-OE1 3.09Å; R56-E82 IonicContact NH1-OE2 2.83Å; R56-E82 PolarHBondContact NH1-OE2 2.89Å; R56-F105 CarbonylContact O-C 3.5Å; R56-F105 WeakPolarHBondContact O-CA 3.3Å; R56-V106 PolarHBondContact N-O 2.95Å; R56-V106 PolarHBondContact O-N 3.49Å
57I94.1Very high88.9Confident10 Ų1051.4 Ų51.45%0.05127%0.266CS..EExtended strand (participates in β ladder)trans-104.2115.8-172.2-52.3174.8000108.6E82 L83 L86 L103 F105I57-E82 CarbonylContact O-C 3.55Å; I57-E82 WeakPolarHBondContact O-CA 3.36Å; I57-L83 HydrophobicContact CB-CB 3.96Å; I57-L83 HydrophobicContact CG2-CB 4.03Å; I57-L83 HydrophobicContact CG2-CD1 3.81Å; I57-L83 PolarHBondContact O-N 3.25Å; I57-L86 HydrophobicContact CD1-CD1 4.48Å; I57-L86 HydrophobicContact CD1-CD2 3.84Å; I57-L86 HydrophobicContact CD1-CG 3.8Å; I57-L86 HydrophobicContact CG2-CD2 4.42Å; I57-L103 HydrophobicContact CG2-CB 4.44Å; I57-L103 HydrophobicContact CG2-CD2 4.26Å; I57-F105 HydrophobicContact CD1-CD1 4.41Å; I57-F105 HydrophobicContact CD1-CE1 3.82Å; I57-F105 HydrophobicContact CG1-CD1 3.8Å; I57-F105 HydrophobicContact CG1-CE1 3.7Å
58C93.6Very high89.1Confident0 Ų054.9 Ų54.90%028%0.277CS..EExtended strand (participates in β ladder)trans-108.2141.7177.6-61.40000110.9F70 C79 V104 V106C58-F70 HydrophobicContact CB-CB 4.24Å; C58-F70 HydrophobicContact CB-CD1 3.69Å; C58-F70 HydrophobicContact CB-CE1 4.44Å; C58-F70 HydrophobicContact CB-CG 4.2Å; C58-C79 VanDerWaalsContact CA-SG 3.5Å; C58-C79 HydrophobicContact CB-CB 4.1Å; C58-C79 WeakPolarHBondContact CB-SG 3.49Å; C58-C79 WeakPolarHBondContact SG-CB 3.48Å; C58-C79 CovalentContact SG-SG 2.03Å; C58-C79 PolarHBondContact SG-SG 2.91Å; C58-V104 HydrophobicContact CB-CB 4.43Å; C58-V104 PolarHBondContact N-O 2.98Å; C58-V104 PolarHBondContact O-N 2.74Å; C58-V106 HydrophobicContact CB-CG2 4.24Å
59V92.4Very high89.3Confident8 Ų854.1 Ų54.15%0.04827%0.266CS..EExtended strand (participates in β ladder)trans-92.5121.8178.1-1770000111.1R61 E81 L83 E102V59-R61 HydrophobicContact CG1-CG 4.23Å; V59-E81 HydrophobicContact CB-CB 4.02Å; V59-E81 HydrophobicContact CB-CG 3.84Å; V59-E81 HydrophobicContact CG2-CB 4.35Å; V59-E81 HydrophobicContact CG2-CG 3.74Å; V59-E81 PolarHBondContact N-O 3.3Å; V59-L83 HydrophobicContact CG2-CD1 3.27Å; V59-L83 HydrophobicContact CG2-CG 4.08Å; V59-E102 CarbonylContact C-O 3.45Å; V59-E102 WeakPolarHBondContact CA-O 3.24Å; V59-E102 HydrophobicContact CG1-CG 3.73Å
60D91.4Very high89.7Confident0 Ų053 Ų530%026%0.257CS..  trans-112.490.6176.3-170.714.3000112.9S62 L63 G64 R68 F70 E102 V104 R219D60-S62 VanDerWaalsContact CG-OG 3.3Å; D60-S62 PolarHBondContact O-N 3.48Å; D60-S62 VanDerWaalsContact O-N 3.13Å; D60-S62 WeakPolarHBondContact OD1-CB 3.48Å; D60-S62 PolarHBondContact OD1-N 3.38Å; D60-S62 VanDerWaalsContact OD1-N 3.11Å; D60-S62 PolarHBondContact OD1-OG 3.31Å; D60-S62 PolarHBondContact OD2-OG 3.47Å; D60-L63 PolarHBondContact O-N 3.5Å; D60-G64 WeakPolarHBondContact OD2-CA 3.32Å; D60-G64 PolarHBondContact OD2-N 2.97Å; D60-R68 IonicContact OD1-CZ 3.49Å; D60-R68 IonicContact OD1-NE 3.4Å; D60-R68 PolarHBondContact OD1-NE 3.03Å; D60-R68 IonicContact OD1-NH2 3.96Å; D60-R68 PolarHBondContact OD1-NH2 3.36Å; D60-F70 HydrophobicContact CB-CE1 4.03Å; D60-F70 HydrophobicContact CB-CE2 3.8Å; D60-F70 HydrophobicContact CB-CZ 3.29Å; D60-F70 WeakPolarHBondContact OD1-CZ 3.23Å; D60-F70 WeakPolarHBondContact OD2-CE2 3.35Å; D60-E102 PolarHBondContact N-O 2.87Å; D60-V104 HydrophobicContact CB-CG2 3.72Å; D60-R219 IonicContact OD2-CZ 3.34Å; D60-R219 IonicContact OD2-NE 3.73Å; D60-R219 IonicContact OD2-NH2 3.07Å; D60-R219 PolarHBondContact OD2-NH2 2.95Å
61R88.1Confident89.9Confident150 Ų15050.3 Ų50.357%0.56625%0.246SC*.THydrogen-bonded Turntrans-64.6-16176.5-56.5-177.8-173.5-170.3-2.7114.1V59 L63 E81V59-R61 HydrophobicContact CG1-CG 4.23Å; R61-L63 VanDerWaalsContact C-N 3.29Å; R61-E81 IonicContact CZ-OE2 3.31Å; R61-E81 VanDerWaalsContact CZ-OE2 3.31Å; R61-E81 IonicContact NE-OE2 3.1Å; R61-E81 PolarHBondContact NE-OE2 3Å; R61-E81 VanDerWaalsContact NE-OE2 3.1Å; R61-E81 IonicContact NH2-OE1 3.36Å; R61-E81 PolarHBondContact NH2-OE1 2.96Å; R61-E81 IonicContact NH2-OE2 2.74Å; R61-E81 PolarHBondContact NH2-OE2 3.1Å
62S87.6Confident89.8Confident20 Ų2048.3 Ų48.314%0.1424%0.236CC..THydrogen-bonded Turntrans-82-6176.177.10000113.3D60 G64 Q65 D66D60-S62 VanDerWaalsContact CG-OG 3.3Å; D60-S62 PolarHBondContact O-N 3.48Å; D60-S62 VanDerWaalsContact O-N 3.13Å; D60-S62 WeakPolarHBondContact OD1-CB 3.48Å; D60-S62 PolarHBondContact OD1-N 3.38Å; D60-S62 VanDerWaalsContact OD1-N 3.11Å; D60-S62 PolarHBondContact OD1-OG 3.31Å; D60-S62 PolarHBondContact OD2-OG 3.47Å; S62-G64 PolarHBondContact O-N 2.87Å; S62-G64 VanDerWaalsContact O-N 3.14Å; S62-G64 PolarHBondContact OG-N 2.9Å; S62-Q65 WeakPolarHBondContact O-CB 3.43Å; S62-Q65 VanDerWaalsContact O-CG 3.28Å; S62-Q65 WeakPolarHBondContact O-CG 3.4Å; S62-Q65 PolarHBondContact O-N 2.96Å; S62-D66 WeakPolarHBondContact CB-OD2 3.41Å
63L84.3Confident89.6Confident50 Ų5047.3 Ų47.326%0.26223%0.227SC..THydrogen-bonded Turntrans52.832.1-175.4-59176.3000113.2D60 R61 Q65 T97 D99 R101 E102D60-L63 PolarHBondContact O-N 3.5Å; R61-L63 VanDerWaalsContact C-N 3.29Å; L63-Q65 VanDerWaalsContact C-N 3.35Å; L63-Q65 PolarHBondContact O-N 3.49Å; L63-T97 HydrophobicContact CD1-CG2 4.19Å; L63-T97 HydrophobicContact CD2-CG2 3.96Å; L63-T97 HydrophobicContact CG-CG2 4.09Å; L63-D99 HydrophobicContact CD1-CB 4.36Å; L63-D99 HydrophobicContact CD2-CB 4.04Å; L63-R101 HydrophobicContact CD2-CB 4.18Å; L63-E102 HydrophobicContact CD2-CB 3.94Å
64G82.5Confident89Confident22 Ų2249.7 Ų49.723%0.22724%0.243CC..THydrogen-bonded Turntrans79.24.7-179.100000116.4D60 S62 D66 G67D60-G64 WeakPolarHBondContact OD2-CA 3.32Å; D60-G64 PolarHBondContact OD2-N 2.97Å; S62-G64 PolarHBondContact O-N 2.87Å; S62-G64 VanDerWaalsContact O-N 3.14Å; S62-G64 PolarHBondContact OG-N 2.9Å; G64-D66 VanDerWaalsContact C-N 3.26Å; G64-D66 PolarHBondContact O-N 3.31Å; G64-G67 PolarHBondContact O-N 2.88Å
65Q82.1Confident88.3Confident168 Ų16851.8 Ų51.879%0.78526%0.255SS*.THydrogen-bonded Turntrans-63.7-32.1179.4-67.9-179.48.900112.8S62 L63 G67S62-Q65 WeakPolarHBondContact O-CB 3.43Å; S62-Q65 VanDerWaalsContact O-CG 3.28Å; S62-Q65 WeakPolarHBondContact O-CG 3.4Å; S62-Q65 PolarHBondContact O-N 2.96Å; L63-Q65 VanDerWaalsContact C-N 3.35Å; L63-Q65 PolarHBondContact O-N 3.49Å; Q65-G67 VanDerWaalsContact C-N 3.28Å; Q65-G67 PolarHBondContact O-N 3.3Å
66D84.7Confident87.6Confident114 Ų11454.3 Ų54.361%0.6127%0.268SS*.THydrogen-bonded Turntrans-79.9-9.8-176.8-62.7-18.4000113.2S62 G64 R68S62-D66 WeakPolarHBondContact CB-OD2 3.41Å; G64-D66 VanDerWaalsContact C-N 3.26Å; G64-D66 PolarHBondContact O-N 3.31Å; D66-R68 HydrophobicContact CB-CG 4.41Å; D66-R68 PolarHBondContact O-N 3.4Å
67G85.1Confident87.1Confident33 Ų3354.8 Ų54.834%0.3428%0.275SS..  trans64.52.7-178.300000115.4G64 Q65 R156G64-G67 PolarHBondContact O-N 2.88Å; Q65-G67 VanDerWaalsContact C-N 3.28Å; Q65-G67 PolarHBondContact O-N 3.3Å; G67-R156 PolarHBondContact O-NH1 3Å; G67-R156 PolarHBondContact O-NH2 3.23Å
68R89.9Confident86.7Confident90 Ų9054.9 Ų54.934%0.3428%0.278SS..PPolyproline II helixtrans-58149-177.166-179.4174.2155.64.5113.5D60 D66 F70D60-R68 IonicContact OD1-CZ 3.49Å; D60-R68 IonicContact OD1-NE 3.4Å; D60-R68 PolarHBondContact OD1-NE 3.03Å; D60-R68 IonicContact OD1-NH2 3.96Å; D60-R68 PolarHBondContact OD1-NH2 3.36Å; D66-R68 HydrophobicContact CB-CG 4.41Å; D66-R68 PolarHBondContact O-N 3.4Å; R68-F70 HydrophobicContact CG-CE2 3.82Å; R68-F70 HydrophobicContact CG-CZ 3.91Å; R68-F70 VanDerWaalsContact CZ-CZ 3.45Å
69W92Very high86.5Confident37 Ų3755 Ų5514%0.1428%0.279CS..PPolyproline II helixtrans-88.6126.2172.6-71.6106.4000110.2R156 W169 E171 L215W69-R156 HydrophobicContact CH2-CB 3.77Å; W69-R156 HydrophobicContact CZ3-CB 3.75Å; W69-W169 HydrophobicContact CB-CB 4.12Å; W69-W169 HydrophobicContact CB-CG 4.41Å; W69-W169 HydrophobicContact CD2-CB 4.09Å; W69-W169 HydrophobicContact CG-CB 3.7Å; W69-W169 HydrophobicContact CG-CG 4.44Å; W69-W169 PolarHBondContact NE1-O 3.24Å; W69-E171 HydrophobicContact CH2-CG 4.3Å; W69-E171 HydrophobicContact CZ2-CB 3.77Å; W69-E171 HydrophobicContact CZ2-CG 3.87Å; W69-L215 HydrophobicContact CB-CD2 4.15Å; W69-L215 HydrophobicContact CD2-CD2 4.32Å; W69-L215 HydrophobicContact CE3-CD2 3.76Å; W69-L215 HydrophobicContact CE3-CG 4.46Å
70F93.4Very high86.1Confident3 Ų362.8 Ų62.81%0.01332%0.315CS..PPolyproline II helixtrans-88.1124.3168.6-66.1-89.6000109.4C58 D60 R68 G78 V104 V106 L215 N217C58-F70 HydrophobicContact CB-CB 4.24Å; C58-F70 HydrophobicContact CB-CD1 3.69Å; C58-F70 HydrophobicContact CB-CE1 4.44Å; C58-F70 HydrophobicContact CB-CG 4.2Å; D60-F70 HydrophobicContact CB-CE1 4.03Å; D60-F70 HydrophobicContact CB-CE2 3.8Å; D60-F70 HydrophobicContact CB-CZ 3.29Å; D60-F70 WeakPolarHBondContact OD1-CZ 3.23Å; D60-F70 WeakPolarHBondContact OD2-CE2 3.35Å; R68-F70 HydrophobicContact CG-CE2 3.82Å; R68-F70 HydrophobicContact CG-CZ 3.91Å; R68-F70 VanDerWaalsContact CZ-CZ 3.45Å; F70-G78 WeakPolarHBondContact CA-O 3.43Å; F70-G78 WeakPolarHBondContact CD1-O 3.32Å; F70-V104 HydrophobicContact CB-CG1 4.33Å; F70-V104 HydrophobicContact CD2-CB 4.23Å; F70-V104 HydrophobicContact CD2-CG1 3.98Å; F70-V104 HydrophobicContact CD2-CG2 3.98Å; F70-V104 HydrophobicContact CE2-CG2 3.97Å; F70-V104 HydrophobicContact CG-CB 4.36Å; F70-V104 HydrophobicContact CG-CG1 4.26Å; F70-V104 HydrophobicContact CG-CG2 4.47Å; F70-V104 HydrophobicContact CZ-CG2 4.43Å; F70-V106 HydrophobicContact CB-CG2 3.61Å; F70-V106 WeakPolarHBondContact O-CG1 3.34Å; F70-L215 WeakPolarHBondContact O-CD2 3.32Å; F70-N217 PolarHBondContact N-ND2 3.34Å; F70-N217 VanDerWaalsContact N-ND2 3.11Å; F70-N217 PolarHBondContact O-ND2 2.87Å; F70-N217 PolarHBondContact O-OD1 3.32Å; F70-N217 VanDerWaalsContact O-OD1 3.12Å
71Y92.4Very high86Confident21 Ų2166 Ų668%0.08233%0.33CS..  trans-141.8152.9176.261.5-91.2000109.1R73 E77 G78 C79 D167 W169Y71-R73 WeakPolarHBondContact CD2-O 3.37Å; Y71-E77 HydrophobicContact CE2-CB 4.28Å; Y71-G78 CarbonylContact O-C 3.27Å; Y71-G78 VanDerWaalsContact O-C 3.27Å; Y71-G78 WeakPolarHBondContact O-CA 3.17Å; Y71-C79 WeakPolarHBondContact O-CB 3.29Å; Y71-C79 PolarHBondContact O-N 3.36Å; Y71-D167 HydrophobicContact CE1-CB 4.32Å; Y71-D167 WeakPolarHBondContact OH-CB 3.5Å; Y71-W169 AromaticContact CD1-CD1 3.74Å; Y71-W169 AromaticContact CD1-NE1 3.64Å; Y71-W169 AromaticContact CG-NE1 3.61Å
72V88.2Confident86Confident2 Ų262 Ų621%0.01232%0.317CS..  trans-98.5-39.1-172.21760000110.4R56 N76 V106R56-V72 HydrophobicContact CB-CG2 3.95Å; R56-V72 VanDerWaalsContact CD-CG1 3.48Å; R56-V72 HydrophobicContact CG-CG2 4.4Å; V72-N76 WeakPolarHBondContact CG1-OD1 3.15Å; V72-N76 WeakPolarHBondContact O-CA 3.31Å; V72-N76 PolarHBondContact O-N 3.03Å; V72-N76 PolarHBondContact O-OD1 2.79Å; V72-V106 HydrophobicContact CG2-CG1 4.23Å
73R87Confident86.1Confident53 Ų5362.2 Ų62.220%0.232%0.317CS..THydrogen-bonded Turntrans-112.3137.4-176.8-59-178-67-84.44.2111.1Y71 Q108 P110Y71-R73 WeakPolarHBondContact CD2-O 3.37Å; R73-Q108 PolarHBondContact NH2-O 3.4Å; R73-Q108 PolarHBondContact O-NE2 3.46Å; R73-Q108 VanDerWaalsContact O-NE2 3.16Å; R73-P110 PolarHBondContact NH2-O 2.93Å
74P79.7Confident86.1Confident53 Ų5369.6 Ų69.634%0.34435%0.35SS..THydrogen-bonded Turncis-84.5151.90.133.5-33.3000113.9N76 E77 P166P74-N76 VanDerWaalsContact C-N 3.3Å; P74-N76 PolarHBondContact O-N 3.28Å; P74-N76 VanDerWaalsContact O-N 3.1Å; P74-E77 PolarHBondContact O-N 2.73Å; P74-P166 VanDerWaalsContact CD-CB 3.44Å; P74-P166 HydrophobicContact CG-CB 3.68Å; P74-P166 HydrophobicContact CG-CG 4.1Å
75N78.2Confident86.2Confident143 Ų14372.7 Ų72.777%0.76536%0.361SS*.THydrogen-bonded Turntrans52.827.3168.5-62.9-14.9000117.9E77N75-E77 HydrophobicContact CB-CG 4.3Å; N75-E77 PolarHBondContact O-N 3.18Å
76N79.6Confident86.4Confident59 Ų5966 Ų6632%0.31633%0.331SS..THydrogen-bonded Turntrans55.321.1180-68.21.4000114.3V72 P74 G78 C79 Q80 E82V72-N76 WeakPolarHBondContact CG1-OD1 3.15Å; V72-N76 WeakPolarHBondContact O-CA 3.31Å; V72-N76 PolarHBondContact O-N 3.03Å; V72-N76 PolarHBondContact O-OD1 2.79Å; P74-N76 VanDerWaalsContact C-N 3.3Å; P74-N76 PolarHBondContact O-N 3.28Å; P74-N76 VanDerWaalsContact O-N 3.1Å; N76-G78 VanDerWaalsContact C-N 3.26Å; N76-G78 PolarHBondContact O-N 2.79Å; N76-C79 CarbonylContact O-C 3.1Å; N76-C79 PolarHBondContact O-N 2.91Å; N76-Q80 PolarHBondContact O-N 3.03Å; N76-E82 PolarHBondContact ND2-OE2 3.28Å
77E83.1Confident86.1Confident115 Ų11561.5 Ų61.554%0.53731%0.312SS..THydrogen-bonded Turntrans-61-37.2-177-68.6-178.4171.900112.1Y71 P74 N75 C79Y71-E77 HydrophobicContact CE2-CB 4.28Å; P74-E77 PolarHBondContact O-N 2.73Å; N75-E77 HydrophobicContact CB-CG 4.3Å; N75-E77 PolarHBondContact O-N 3.18Å; E77-C79 VanDerWaalsContact C-N 3.33Å
78G84.7Confident85.6Confident11 Ų1168.3 Ų68.311%0.11333%0.327CS..THydrogen-bonded Turntrans-80.6-9.417600000114.6F70 Y71 N76F70-G78 WeakPolarHBondContact CA-O 3.43Å; F70-G78 WeakPolarHBondContact CD1-O 3.32Å; Y71-G78 CarbonylContact O-C 3.27Å; Y71-G78 VanDerWaalsContact O-C 3.27Å; Y71-G78 WeakPolarHBondContact O-CA 3.17Å; N76-G78 VanDerWaalsContact C-N 3.26Å; N76-G78 PolarHBondContact O-N 2.79Å
79C90Very high84.6Confident2 Ų267.1 Ų67.11%0.01433%0.331CS..  trans-13767.8-176.3-173.40000109.2C58 Y71 N76 E77 E81C58-C79 VanDerWaalsContact CA-SG 3.5Å; C58-C79 HydrophobicContact CB-CB 4.1Å; C58-C79 WeakPolarHBondContact CB-SG 3.49Å; C58-C79 WeakPolarHBondContact SG-CB 3.48Å; C58-C79 CovalentContact SG-SG 2.03Å; C58-C79 PolarHBondContact SG-SG 2.91Å; Y71-C79 WeakPolarHBondContact O-CB 3.29Å; Y71-C79 PolarHBondContact O-N 3.36Å; N76-C79 CarbonylContact O-C 3.1Å; N76-C79 PolarHBondContact O-N 2.91Å; E77-C79 VanDerWaalsContact C-N 3.33Å; C79-E81 PolarHBondContact O-N 3.49Å
80Q84.9Confident83.6Confident173 Ų17373.4 Ų73.481%0.80836%0.362SS*.SBendtrans-59.5-31.4-174-65.7179.8-12.300113.3N76N76-Q80 PolarHBondContact O-N 3.03Å
81E88.5Confident82.8Confident67 Ų6778.4 Ų78.431%0.31339%0.392SS..SBendtrans-122.396.7177.9-174.9171.8-162.800107.7V59 R61 C79V59-E81 HydrophobicContact CB-CB 4.02Å; V59-E81 HydrophobicContact CB-CG 3.84Å; V59-E81 HydrophobicContact CG2-CB 4.35Å; V59-E81 HydrophobicContact CG2-CG 3.74Å; V59-E81 PolarHBondContact N-O 3.3Å; R61-E81 IonicContact CZ-OE2 3.31Å; R61-E81 VanDerWaalsContact CZ-OE2 3.31Å; R61-E81 IonicContact NE-OE2 3.1Å; R61-E81 PolarHBondContact NE-OE2 3Å; R61-E81 VanDerWaalsContact NE-OE2 3.1Å; R61-E81 IonicContact NH2-OE1 3.36Å; R61-E81 PolarHBondContact NH2-OE1 2.96Å; R61-E81 IonicContact NH2-OE2 2.74Å; R61-E81 PolarHBondContact NH2-OE2 3.1Å; C79-E81 PolarHBondContact O-N 3.49Å
82E88.1Confident82Confident65 Ų6580.6 Ų80.630%0.30441%0.409SS..EExtended strand (participates in β ladder)trans-100.2134.4176.8-174.8176.9-170.400109.5R56 I57 N76R56-E82 WeakPolarHBondContact CD-OE1 3.28Å; R56-E82 WeakPolarHBondContact CG-OE1 3.4Å; R56-E82 IonicContact CZ-OE1 3.34Å; R56-E82 IonicContact NE-OE1 3.62Å; R56-E82 IonicContact NH1-OE1 3.52Å; R56-E82 PolarHBondContact NH1-OE1 3.09Å; R56-E82 IonicContact NH1-OE2 2.83Å; R56-E82 PolarHBondContact NH1-OE2 2.89Å; I57-E82 CarbonylContact O-C 3.55Å; I57-E82 WeakPolarHBondContact O-CA 3.36Å; N76-E82 PolarHBondContact ND2-OE2 3.28Å
83L88.9Confident81.6Confident26 Ų2683.4 Ų83.414%0.13642%0.422CS..EExtended strand (participates in β ladder)trans-100.8130.7175.3-76.5143.2000109.7I57 V59 H93 L103I57-L83 HydrophobicContact CB-CB 3.96Å; I57-L83 HydrophobicContact CG2-CB 4.03Å; I57-L83 HydrophobicContact CG2-CD1 3.81Å; I57-L83 PolarHBondContact O-N 3.25Å; V59-L83 HydrophobicContact CG2-CD1 3.27Å; V59-L83 HydrophobicContact CG2-CG 4.08Å; L83-H93 VanDerWaalsContact CD2-CE1 3.43Å; L83-H93 WeakPolarHBondContact CD2-CE1 3.41Å; L83-H93 VanDerWaalsContact CD2-ND1 3.35Å; L83-H93 WeakPolarHBondContact CD2-ND1 3.4Å; L83-L103 HydrophobicContact CD1-CD2 3.81Å
84E85.5Confident81.1Confident204 Ų20485.2 Ų85.295%0.95344%0.443SS*.SBendtrans-72.2-40.1172.6-67.5-175.1171.500111.5
85D84.9Confident81.2Confident87 Ų8785.3 Ų85.347%0.46544%0.44SS..  trans-143.9170.2177.469.519.4000111.6G87D85-G87 PolarHBondContact O-N 3.32Å; D85-G87 VanDerWaalsContact OD1-CA 3.3Å; D85-G87 WeakPolarHBondContact OD1-CA 3.32Å; D85-G87 PolarHBondContact OD1-N 3.42Å
86L84.9Confident81.3Confident27 Ų2784.1 Ų84.114%0.14143%0.433CS..SBendtrans-82.616.2174-67.7173.3000112.9I57 H93 L103 F105 L236I57-L86 HydrophobicContact CD1-CD1 4.48Å; I57-L86 HydrophobicContact CD1-CD2 3.84Å; I57-L86 HydrophobicContact CD1-CG 3.8Å; I57-L86 HydrophobicContact CG2-CD2 4.42Å; L86-H93 PolarHBondContact O-N 3.32Å; L86-H93 VanDerWaalsContact O-N 3.14Å; L86-L103 HydrophobicContact CD2-CD1 3.57Å; L86-F105 HydrophobicContact CD1-CZ 4.31Å; L86-L236 HydrophobicContact CD1-CB 4.36Å; L86-L236 HydrophobicContact CD1-CD2 4.31Å; L86-L236 HydrophobicContact CD1-CG 4.16Å; L86-L236 VanDerWaalsContact CD1-O 3.31Å; L86-L236 WeakPolarHBondContact CD1-O 3.46Å
87G79.5Confident81.1Confident20 Ų2084 Ų8421%0.20643%0.434CS..BIsolated β-bridgetrans79.4177.7-173.100000113.8D85 R235D85-G87 PolarHBondContact O-N 3.32Å; D85-G87 VanDerWaalsContact OD1-CA 3.3Å; D85-G87 WeakPolarHBondContact OD1-CA 3.32Å; D85-G87 PolarHBondContact OD1-N 3.42Å; G87-R235 PolarHBondContact O-NH2 3.33Å
88R75.2Confident80.9Confident177 Ų17781.3 Ų81.367%0.66844%0.438SS*.  trans-89.1163.6178-68.6-175.3-174.6171.72.3112E90 V91 R235R88-E90 PolarHBondContact O-N 2.97Å; R88-V91 PolarHBondContact N-O 3.44Å; R88-V91 CarbonylContact O-C 3.59Å; R88-V91 PolarHBondContact O-N 3.26Å; R88-V91 VanDerWaalsContact O-N 3.15Å; R88-R235 PolarHBondContact O-NH2 3.19Å; R88-R235 VanDerWaalsContact O-NH2 3.16Å
89P68.4Low80.8Confident65 Ų6581.4 Ų81.442%0.42244%0.435SS..SBendtrans-51.6-36.8175.2-29.936.6000114.6R235P89-R235 VanDerWaalsContact CA-NH1 3.28Å
90E69.7Low80.6Confident169 Ų16983.4 Ų83.479%0.7945%0.448SS*.SBendtrans-78.2-29.6-177.4-64.2156.7-17100113R88R88-E90 PolarHBondContact O-N 2.97Å
91V77.9Confident80.7Confident107 Ų10778.8 Ų78.865%0.64842%0.423SS*.SBendtrans-138.677.4-176.3-170.10000107.7R88R88-V91 PolarHBondContact N-O 3.44Å; R88-V91 CarbonylContact O-C 3.59Å; R88-V91 PolarHBondContact O-N 3.26Å; R88-V91 VanDerWaalsContact O-N 3.15Å
92P76.4Confident80.8Confident67 Ų6775.6 Ų75.644%0.43541%0.409SS..BIsolated β-bridgetrans-65.4151.6175.628.6-34.1000109.8S94P92-S94 PolarHBondContact O-N 3.45Å
93H79.4Confident81Confident61 Ų6173.5 Ų73.528%0.28240%0.4SS..  trans-58128.2173.9-174.769.6000110.8L83 L86 L95L83-H93 VanDerWaalsContact CD2-CE1 3.43Å; L83-H93 WeakPolarHBondContact CD2-CE1 3.41Å; L83-H93 VanDerWaalsContact CD2-ND1 3.35Å; L83-H93 WeakPolarHBondContact CD2-ND1 3.4Å; L86-H93 PolarHBondContact O-N 3.32Å; L86-H93 VanDerWaalsContact O-N 3.14Å; H93-L95 PolarHBondContact O-N 3.01Å
94S76.8Confident81.2Confident92 Ų9272.3 Ų72.364%0.64339%0.393SS*.  trans-83.7109-178.258.60000110.6P92 I96P92-S94 PolarHBondContact O-N 3.45Å; S94-I96 PolarHBondContact O-N 3.4Å
95L81.2Confident81.7Confident54 Ų5462.8 Ų62.828%0.28335%0.349SS..  trans-67119172.5-62.8163.4000109.6H93 T97 G98 P100 E102 L103H93-L95 PolarHBondContact O-N 3.01Å; L95-T97 VanDerWaalsContact C-N 3.31Å; L95-T97 PolarHBondContact O-N 2.84Å; L95-G98 PolarHBondContact O-N 3.5Å; L95-P100 HydrophobicContact CD1-CG 4.18Å; L95-E102 HydrophobicContact CD2-CB 4.11Å; L95-E102 HydrophobicContact CD2-CG 4.48Å; L95-L103 HydrophobicContact CD2-CD1 4.1Å; L95-L103 HydrophobicContact CD2-CD2 4.06Å; L95-L103 HydrophobicContact CD2-CG 3.82Å
96I79.1Confident82.2Confident118 Ų11858.8 Ų58.861%0.60533%0.327SS*.SBendtrans-66.1-40.8-178.4-62.7174.2000110S94 G98 E102S94-I96 PolarHBondContact O-N 3.4Å; I96-G98 VanDerWaalsContact C-N 3.32Å; I96-E102 PolarHBondContact N-OE2 2.65Å
97T76.2Confident82.7Confident57 Ų5757.6 Ų57.635%0.3532%0.321SS..SBendtrans-79.3-18.4-179.461.80000112.9L63 L95 D99 E102L63-T97 HydrophobicContact CD1-CG2 4.19Å; L63-T97 HydrophobicContact CD2-CG2 3.96Å; L63-T97 HydrophobicContact CG-CG2 4.09Å; L95-T97 VanDerWaalsContact C-N 3.31Å; L95-T97 PolarHBondContact O-N 2.84Å; T97-D99 PolarHBondContact O-N 2.9Å; T97-D99 PolarHBondContact OG1-N 3.48Å; T97-D99 PolarHBondContact OG1-O 3.43Å; T97-E102 WeakPolarHBondContact CB-OE2 3.35Å; T97-E102 WeakPolarHBondContact CG2-OE2 3.41Å; T97-E102 PolarHBondContact N-OE2 2.7Å; T97-E102 PolarHBondContact OG1-OE2 3.29Å
98G78.7Confident83.4Confident59 Ų5957.3 Ų57.361%0.60832%0.315SS*.SBendtrans72.8-0.6-169.400000114.5L95 I96L95-G98 PolarHBondContact O-N 3.5Å; I96-G98 VanDerWaalsContact C-N 3.32Å
99D82.8Confident84.2Confident13 Ų1348.9 Ų48.97%0.0728%0.283CS..  trans-104123.7176.7-169.6-22.2000109.9L63 T97 R101 E102 N224L63-D99 HydrophobicContact CD1-CB 4.36Å; L63-D99 HydrophobicContact CD2-CB 4.04Å; T97-D99 PolarHBondContact O-N 2.9Å; T97-D99 PolarHBondContact OG1-N 3.48Å; T97-D99 PolarHBondContact OG1-O 3.43Å; D99-R101 PolarHBondContact O-N 2.84Å; D99-R101 WeakPolarHBondContact OD1-CB 3.49Å; D99-R101 WeakPolarHBondContact OD1-CG 3.35Å; D99-R101 PolarHBondContact OD1-N 3.23Å; D99-E102 VanDerWaalsContact O-CB 3.28Å; D99-E102 WeakPolarHBondContact O-CB 2.88Å; D99-E102 PolarHBondContact O-N 2.97Å; D99-N224 PolarHBondContact OD2-ND2 2.91Å; D99-N224 PolarHBondContact OD2-OD1 3.4Å
100P85.4Confident85.4Confident44 Ų4446 Ų4629%0.28626%0.264SS..G310 helixtrans-55.8-17.8174-28.537.5000115.2L95 E102 L103L95-P100 HydrophobicContact CD1-CG 4.18Å; P100-E102 PolarHBondContact O-N 3.15Å; P100-E102 VanDerWaalsContact O-N 3.15Å; P100-L103 PolarHBondContact O-N 3.43Å
101R87.2Confident86.3Confident75 Ų7540.1 Ų40.128%0.28324%0.238SC..G310 helixtrans-60.9-16.1171.8-71.3-179.5171.3-165.5-4.2114.2L63 D99 L103 E154 P221L63-R101 HydrophobicContact CD2-CB 4.18Å; D99-R101 PolarHBondContact O-N 2.84Å; D99-R101 WeakPolarHBondContact OD1-CB 3.49Å; D99-R101 WeakPolarHBondContact OD1-CG 3.35Å; D99-R101 PolarHBondContact OD1-N 3.23Å; R101-L103 PolarHBondContact O-N 2.79Å; R101-E154 IonicContact CZ-OE1 3.53Å; R101-E154 IonicContact NE-OE1 3.87Å; R101-E154 PolarHBondContact NE-OE1 3.18Å; R101-E154 IonicContact NE-OE2 3.71Å; R101-E154 IonicContact NH2-OE1 2.71Å; R101-E154 PolarHBondContact NH2-OE1 3.22Å; R101-P221 HydrophobicContact CG-CB 4.1Å
102E90.5Very high86.7Confident1 Ų137.8 Ų37.81%0.00523%0.225CC..G310 helixtrans-60.9-23.2171.1-180169.6-177.800112V59 D60 L63 L95 I96 T97 D99 P100V59-E102 CarbonylContact C-O 3.45Å; V59-E102 WeakPolarHBondContact CA-O 3.24Å; V59-E102 HydrophobicContact CG1-CG 3.73Å; D60-E102 PolarHBondContact N-O 2.87Å; L63-E102 HydrophobicContact CD2-CB 3.94Å; L95-E102 HydrophobicContact CD2-CB 4.11Å; L95-E102 HydrophobicContact CD2-CG 4.48Å; I96-E102 PolarHBondContact N-OE2 2.65Å; T97-E102 WeakPolarHBondContact CB-OE2 3.35Å; T97-E102 WeakPolarHBondContact CG2-OE2 3.41Å; T97-E102 PolarHBondContact N-OE2 2.7Å; T97-E102 PolarHBondContact OG1-OE2 3.29Å; D99-E102 VanDerWaalsContact O-CB 3.28Å; D99-E102 WeakPolarHBondContact O-CB 2.88Å; D99-E102 PolarHBondContact O-N 2.97Å; P100-E102 PolarHBondContact O-N 3.15Å; P100-E102 VanDerWaalsContact O-N 3.15Å
103L92.3Very high87.1Confident21 Ų2143 Ų4311%0.1124%0.236CC..EExtended strand (participates in β ladder)trans-93.7126.5177.2-53.1178.9000110.9I57 L83 L86 L95 P100 R101 F105I57-L103 HydrophobicContact CG2-CB 4.44Å; I57-L103 HydrophobicContact CG2-CD2 4.26Å; L83-L103 HydrophobicContact CD1-CD2 3.81Å; L86-L103 HydrophobicContact CD2-CD1 3.57Å; L95-L103 HydrophobicContact CD2-CD1 4.1Å; L95-L103 HydrophobicContact CD2-CD2 4.06Å; L95-L103 HydrophobicContact CD2-CG 3.82Å; P100-L103 PolarHBondContact O-N 3.43Å; R101-L103 PolarHBondContact O-N 2.79Å; L103-F105 HydrophobicContact CB-CE2 4.48Å
104V94.2Very high87.2Confident0 Ų046.5 Ų46.50%026%0.257CS..EExtended strand (participates in β ladder)trans-117.6114.9175.2-170.30000108.9C58 D60 F70 V106 N217 R219C58-V104 HydrophobicContact CB-CB 4.43Å; C58-V104 PolarHBondContact N-O 2.98Å; C58-V104 PolarHBondContact O-N 2.74Å; D60-V104 HydrophobicContact CB-CG2 3.72Å; F70-V104 HydrophobicContact CB-CG1 4.33Å; F70-V104 HydrophobicContact CD2-CB 4.23Å; F70-V104 HydrophobicContact CD2-CG1 3.98Å; F70-V104 HydrophobicContact CD2-CG2 3.98Å; F70-V104 HydrophobicContact CE2-CG2 3.97Å; F70-V104 HydrophobicContact CG-CB 4.36Å; F70-V104 HydrophobicContact CG-CG1 4.26Å; F70-V104 HydrophobicContact CG-CG2 4.47Å; F70-V104 HydrophobicContact CZ-CG2 4.43Å; V104-V106 HydrophobicContact CG1-CG2 4.04Å; V104-N217 HydrophobicContact CG1-CB 3.93Å; V104-R219 HydrophobicContact CG1-CG 4.39Å; V104-R219 HydrophobicContact CG2-CG 4.02Å
105F95.5Very high87.2Confident5 Ų550.5 Ų50.52%0.02227%0.271CS..EExtended strand (participates in β ladder)trans-84.1124.1173.1-62.4-93000108.9M55 R56 I57 L86 L103 N217 I218 I220 L236 L239M55-F105 HydrophobicContact CB-CB 4.09Å; M55-F105 HydrophobicContact CB-CD1 4.44Å; M55-F105 VanDerWaalsContact CE-C 3.42Å; M55-F105 HydrophobicContact CE-CB 3.6Å; M55-F105 WeakPolarHBondContact CE-O 3.45Å; M55-F105 HydrophobicContact SD-CB 3.88Å; R56-F105 CarbonylContact O-C 3.5Å; R56-F105 WeakPolarHBondContact O-CA 3.3Å; I57-F105 HydrophobicContact CD1-CD1 4.41Å; I57-F105 HydrophobicContact CD1-CE1 3.82Å; I57-F105 HydrophobicContact CG1-CD1 3.8Å; I57-F105 HydrophobicContact CG1-CE1 3.7Å; L86-F105 HydrophobicContact CD1-CZ 4.31Å; L103-F105 HydrophobicContact CB-CE2 4.48Å; F105-N217 CarbonylContact O-C 3.59Å; F105-N217 WeakPolarHBondContact O-CA 3.22Å; F105-I218 HydrophobicContact CB-CB 4.34Å; F105-I218 PolarHBondContact N-O 3.4Å; F105-I218 PolarHBondContact O-N 3.21Å; F105-I220 HydrophobicContact CD2-CD1 4.45Å; F105-I220 HydrophobicContact CD2-CG1 4.5Å; F105-I220 HydrophobicContact CE2-CD1 3.98Å; F105-I220 HydrophobicContact CE2-CG1 4.26Å; F105-L236 HydrophobicContact CE1-CD2 4.32Å; F105-L236 HydrophobicContact CE2-CD2 4.14Å; F105-L236 HydrophobicContact CZ-CD2 3.59Å; F105-L239 HydrophobicContact CB-CD1 3.89Å; F105-L239 HydrophobicContact CD1-CB 4.17Å; F105-L239 HydrophobicContact CD1-CD1 3.59Å; F105-L239 HydrophobicContact CD1-CG 3.93Å; F105-L239 HydrophobicContact CD2-CD1 3.66Å; F105-L239 HydrophobicContact CE1-CD1 3.98Å; F105-L239 HydrophobicContact CE1-CG 4.05Å; F105-L239 HydrophobicContact CE2-CD1 4.05Å; F105-L239 HydrophobicContact CG-CD1 3.43Å; F105-L239 VanDerWaalsContact CG-CD1 3.43Å; F105-L239 HydrophobicContact CG-CG 4.29Å; F105-L239 HydrophobicContact CZ-CD1 4.2Å
106V95.4Very high87.4Confident3 Ų352.2 Ų52.22%0.01828%0.284CS..EExtended strand (participates in β ladder)trans-118.7123.7-171.7-178.30000110.2M55 R56 C58 F70 V72 V104 L215 L216M55-V106 WeakPolarHBondContact CA-O 3.36Å; R56-V106 PolarHBondContact N-O 2.95Å; R56-V106 PolarHBondContact O-N 3.49Å; C58-V106 HydrophobicContact CB-CG2 4.24Å; F70-V106 HydrophobicContact CB-CG2 3.61Å; F70-V106 WeakPolarHBondContact O-CG1 3.34Å; V72-V106 HydrophobicContact CG2-CG1 4.23Å; V104-V106 HydrophobicContact CG1-CG2 4.04Å; V106-L215 HydrophobicContact CG1-CD1 3.65Å; V106-L216 WeakPolarHBondContact CA-O 3.38Å
107A95.1Very high87.7Confident2 Ų250.2 Ų50.22%0.01727%0.272CS..EExtended strand (participates in β ladder)trans-116.8116.5167.700000109.8M55 L216 I241M55-A107 HydrophobicContact CE-CB 4.08Å; M55-A107 HydrophobicContact CG-CB 4.25Å; A107-L216 HydrophobicContact CB-CB 4.32Å; A107-L216 PolarHBondContact N-O 3.2Å; A107-L216 PolarHBondContact O-N 2.87Å; A107-I241 HydrophobicContact CB-CD1 4.02Å
108Q93.3Very high88.3Confident13 Ų1350.3 Ų50.36%0.06127%0.27CS..EExtended strand (participates in β ladder)trans-104.1111.5175.8-173.9175-1.800109.3R73 W169 L215R73-Q108 PolarHBondContact NH2-O 3.4Å; R73-Q108 PolarHBondContact O-NE2 3.46Å; R73-Q108 VanDerWaalsContact O-NE2 3.16Å; Q108-W169 HydrophobicContact CG-CH2 4.22Å; Q108-W169 HydrophobicContact CG-CZ2 4.23Å; Q108-L215 HydrophobicContact CB-CD1 4.06Å; Q108-L215 HydrophobicContact CG-CD1 4.37Å
109M93.3Very high89Confident1 Ų151.1 Ų51.11%0.00526%0.258CS..EExtended strand (participates in β ladder)trans-110.9136.1-171.6-59178.4-81.700111F53 Y120 F204 F213 Y214 L216 E243F53-M109 HydrophobicContact CD1-CG 3.95Å; F53-M109 HydrophobicContact CD2-CG 4.17Å; F53-M109 HydrophobicContact CD2-SD 4.45Å; F53-M109 HydrophobicContact CE1-CB 4.02Å; F53-M109 HydrophobicContact CE1-CG 3.69Å; F53-M109 HydrophobicContact CE2-CG 3.93Å; F53-M109 HydrophobicContact CE2-SD 4.31Å; F53-M109 HydrophobicContact CG-CG 4.19Å; F53-M109 HydrophobicContact CZ-CB 3.94Å; F53-M109 HydrophobicContact CZ-CG 3.7Å; M109-Y120 HydrophobicContact CB-CE2 3.69Å; M109-F204 HydrophobicContact CE-CE1 4.31Å; M109-F204 HydrophobicContact CE-CZ 4.11Å; M109-F204 HydrophobicContact SD-CZ 4.49Å; M109-F213 WeakPolarHBondContact O-CA 3.42Å; M109-Y214 PolarHBondContact N-O 3.48Å; M109-Y214 PolarHBondContact O-N 3.02Å; M109-Y214 VanDerWaalsContact O-O 3.13Å; M109-L216 HydrophobicContact CE-CB 4.06Å; M109-L216 HydrophobicContact CE-CD2 4.43Å; M109-E243 HydrophobicContact SD-CB 4.32Å; M109-E243 HydrophobicContact SD-CG 4.25Å
110P93.3Very high89.5Confident3 Ų350.8 Ų50.82%0.01926%0.256CS..SBendcis-84165.6-1.835.6-35.7000112.9M51 R73 Q117 L118 Y120M51-P110 HydrophobicContact CE-CB 4.37Å; M51-P110 HydrophobicContact SD-CB 4.33Å; R73-P110 PolarHBondContact NH2-O 2.93Å; P110-Q117 PolarHBondContact O-NE2 3.49Å; P110-L118 HydrophobicContact CB-CB 4.1Å; P110-L118 HydrophobicContact CG-CB 3.74Å; P110-L118 WeakPolarHBondContact CG-O 3.12Å; P110-Y120 HydrophobicContact CB-CD2 4.45Å; P110-Y120 HydrophobicContact CB-CE1 4.27Å; P110-Y120 HydrophobicContact CB-CE2 3.95Å; P110-Y120 HydrophobicContact CG-CD2 4.25Å; P110-Y120 HydrophobicContact CG-CE2 4.19Å
111N87.9Confident89.9Confident47 Ų4750.9 Ų50.925%0.25126%0.257SS..PPolyproline II helixtrans-73.7143.9175.8-86-20.8000110.1M51 N52 F53 L118M51-N111 HydrophobicContact CE-CB 3.93Å; N52-N111 PolarHBondContact O-ND2 3.39Å; F53-N111 HydrophobicContact CD1-CB 4.41Å; F53-N111 VanDerWaalsContact CD1-CG 3.41Å; F53-N111 VanDerWaalsContact CD1-ND2 3.28Å; F53-N111 WeakPolarHBondContact CD1-ND2 3.2Å; F53-N111 WeakPolarHBondContact CD1-OD1 3.37Å; F53-N111 HydrophobicContact CE1-CB 3.86Å; F53-N111 VanDerWaalsContact CE1-N 3.31Å; F53-N111 WeakPolarHBondContact CE1-OD1 3.41Å; N111-L118 WeakPolarHBondContact O-CD1 3.44Å; N111-L118 WeakPolarHBondContact O-CG 3.36Å
112P87.2Confident90.2Very high58 Ų5851.6 Ų51.638%0.37726%0.26SS..PPolyproline II helixtrans-66.4148.6169.830.2-34.2000110V116P112-V116 WeakPolarHBondContact CA-O 3.36Å
113R83.9Confident90.3Very high175 Ų17555.1 Ų55.166%0.6627%0.273SS*.BIsolated β-bridgetrans-135.1130.5176.2-178177.5178.8166.15.9108.7D115 V116 L118R113-D115 VanDerWaalsContact C-N 3.3Å; R113-D115 PolarHBondContact O-N 3.37Å; R113-V116 PolarHBondContact N-O 3.48Å; R113-V116 WeakPolarHBondContact O-CB 3.41Å; R113-V116 PolarHBondContact O-N 2.87Å; R113-L118 HydrophobicContact CB-CD1 3.96Å; R113-L118 HydrophobicContact CB-CG 4.27Å
114D82.1Confident90.3Very high136 Ų13656 Ų5673%0.72728%0.276SS*.THydrogen-bonded Turntrans51.146.7178-53.5-40.5000112.9V116D114-V116 PolarHBondContact O-N 3.18Å
115D77.8Confident90.2Very high176 Ų17656.9 Ų56.994%0.94128%0.281SS*.THydrogen-bonded Turntrans59.910.1-175.2-62.8-40000115.9R113R113-D115 VanDerWaalsContact C-N 3.3Å; R113-D115 PolarHBondContact O-N 3.37Å
116V85.4Confident90Very high90 Ų9058 Ų5855%0.54529%0.289SS..BIsolated β-bridgetrans-100.6123.6173.3-176.20000109.6P112 R113 D114 L118P112-V116 WeakPolarHBondContact CA-O 3.36Å; R113-V116 PolarHBondContact N-O 3.48Å; R113-V116 WeakPolarHBondContact O-CB 3.41Å; R113-V116 PolarHBondContact O-N 2.87Å; D114-V116 PolarHBondContact O-N 3.18Å; V116-L118 PolarHBondContact O-N 3.34Å; V116-L118 VanDerWaalsContact O-N 3.14Å
117Q83.9Confident89.8Confident76 Ų7657.9 Ų57.936%0.35529%0.288SS..  trans-69.6109.9170-179.157.946.800108.8P110 F213P110-Q117 PolarHBondContact O-NE2 3.49Å; Q117-F213 HydrophobicContact CG-CE1 3.87Å; Q117-F213 HydrophobicContact CG-CZ 4.38Å
118L90.1Very high89.7Confident59 Ų5960.1 Ų60.131%0.30930%0.3SS..  trans-69.8156.7173.6-60.1-176.8000110.1M51 P110 N111 R113 V116 F213M51-L118 HydrophobicContact CE-CD1 4.22Å; P110-L118 HydrophobicContact CB-CB 4.1Å; P110-L118 HydrophobicContact CG-CB 3.74Å; P110-L118 WeakPolarHBondContact CG-O 3.12Å; N111-L118 WeakPolarHBondContact O-CD1 3.44Å; N111-L118 WeakPolarHBondContact O-CG 3.36Å; R113-L118 HydrophobicContact CB-CD1 3.96Å; R113-L118 HydrophobicContact CB-CG 4.27Å; V116-L118 PolarHBondContact O-N 3.34Å; V116-L118 VanDerWaalsContact O-N 3.14Å; L118-F213 WeakPolarHBondContact O-CE1 3.09Å
119E92.4Very high89.7Confident75 Ų7559.5 Ų59.535%0.3530%0.297SS..  trans-135.9140.3175.8-55.9-169.7161.100109.6R162 P212 F213E119-R162 IonicContact OE1-NE 3.93Å; E119-R162 IonicContact OE2-CZ 3.17Å; E119-R162 IonicContact OE2-NE 2.64Å; E119-R162 PolarHBondContact OE2-NE 2.94Å; E119-R162 IonicContact OE2-NH2 3.19Å; E119-R162 PolarHBondContact OE2-NH2 3.23Å; E119-P212 HydrophobicContact CB-CB 4.05Å; E119-F213 HydrophobicContact CB-CE1 4.48Å; E119-F213 HydrophobicContact CB-CZ 4.49Å; E119-F213 HydrophobicContact CG-CE1 3.83Å; E119-F213 HydrophobicContact CG-CE2 4.49Å; E119-F213 HydrophobicContact CG-CZ 3.58Å; E119-F213 WeakPolarHBondContact OE1-CZ 3.31Å
120Y93.6Very high89.7Confident7 Ų761 Ų613%0.02730%0.304CS..  trans-69.3150.9168.3-68.8-64.6000111.3M109 P110 F124 L127 P212 Y214 E243M109-Y120 HydrophobicContact CB-CE2 3.69Å; P110-Y120 HydrophobicContact CB-CD2 4.45Å; P110-Y120 HydrophobicContact CB-CE1 4.27Å; P110-Y120 HydrophobicContact CB-CE2 3.95Å; P110-Y120 HydrophobicContact CG-CD2 4.25Å; P110-Y120 HydrophobicContact CG-CE2 4.19Å; Y120-F124 AromaticContact CD1-CD2 3.61Å; Y120-F124 HydrophobicContact CD1-CD2 3.61Å; Y120-F124 AromaticContact CD1-CE2 3.65Å; Y120-F124 HydrophobicContact CD1-CE2 3.65Å; Y120-F124 HydrophobicContact CG-CD2 4.39Å; Y120-F124 HydrophobicContact CG-CE2 4.49Å; Y120-L127 HydrophobicContact CD1-CD1 4.48Å; Y120-L127 HydrophobicContact CE1-CD1 3.98Å; Y120-P212 PolarHBondContact N-O 2.95Å; Y120-P212 WeakPolarHBondContact O-CA 3.47Å; Y120-Y214 AromaticContact CD2-CD2 3.67Å; Y120-Y214 HydrophobicContact CD2-CD2 3.67Å; Y120-Y214 HydrophobicContact CD2-CE2 4.01Å; Y120-Y214 AromaticContact CE2-CD2 3.96Å; Y120-Y214 HydrophobicContact CE2-CD2 3.96Å; Y120-E243 WeakPolarHBondContact CE1-OE2 3.46Å; Y120-E243 VanDerWaalsContact OH-CD 3.27Å; Y120-E243 PolarHBondContact OH-OE2 2.95Å
121S93Very high89.8Confident46 Ų4660.8 Ų60.832%0.32230%0.303SS..  trans-124.3149.6177.4-167.10000110.5W123 F124S121-W123 PolarHBondContact O-N 3.01Å; S121-F124 WeakPolarHBondContact O-CB 3.39Å; S121-F124 WeakPolarHBondContact O-CG 3.47Å; S121-F124 PolarHBondContact O-N 3.39Å
122R93.3Very high90Very high90 Ų9060.7 Ų60.734%0.3430%0.303SS..G310 helixtrans-59.9-18174.1-64-177.4176.1-168.8-4.3113.5F124 Q125 C209 D210 L309 W310R122-F124 PolarHBondContact O-N 3.18Å; R122-Q125 PolarHBondContact O-N 3.06Å; R122-C209 WeakPolarHBondContact CA-O 3.22Å; R122-C209 WeakPolarHBondContact CG-O 3.24Å; R122-D210 PolarHBondContact NE-O 3.46Å; R122-L309 HydrophobicContact CB-CD2 3.99Å; R122-L309 WeakPolarHBondContact CD-O 3.44Å; R122-L309 PolarHBondContact NH1-O 2.96Å; R122-W310 PolarHBondContact NH1-O 3.18Å
123W93.7Very high90.2Very high75 Ų7558.4 Ų58.428%0.28429%0.287SS..G310 helixtrans-61.5-18.8170.6-71.2104.7000114.1S121 Q125 T251 K252 L255 W306 L309S121-W123 PolarHBondContact O-N 3.01Å; W123-Q125 VanDerWaalsContact C-N 3.3Å; W123-T251 HydrophobicContact CE3-CG2 3.99Å; W123-T251 WeakPolarHBondContact O-CB 3.2Å; W123-T251 WeakPolarHBondContact O-CG2 3.5Å; W123-T251 PolarHBondContact O-OG1 3.34Å; W123-K252 HydrophobicContact CE3-CB 4.34Å; W123-K252 HydrophobicContact CH2-CG 4.4Å; W123-K252 HydrophobicContact CZ3-CB 4Å; W123-K252 HydrophobicContact CZ3-CG 4.28Å; W123-L255 HydrophobicContact CZ3-CD1 4.02Å; W123-W306 AromaticContact CH2-CH2 3.76Å; W123-W306 HydrophobicContact CH2-CH2 3.76Å; W123-W306 AromaticContact CH2-CZ3 3.52Å; W123-W306 HydrophobicContact CH2-CZ3 3.52Å; W123-W306 HydrophobicContact CZ2-CZ3 4.34Å; W123-W306 HydrophobicContact CZ3-CH2 4.34Å; W123-W306 HydrophobicContact CZ3-CZ3 4.22Å; W123-L309 HydrophobicContact CD2-CD1 4.31Å; W123-L309 HydrophobicContact CD2-CD2 4Å; W123-L309 HydrophobicContact CE3-CD1 4.28Å; W123-L309 HydrophobicContact CE3-CD2 4.22Å; W123-L309 HydrophobicContact CG-CD2 4.27Å; W123-L309 HydrophobicContact CH2-CD1 3.66Å; W123-L309 HydrophobicContact CZ2-CD1 3.66Å; W123-L309 HydrophobicContact CZ3-CD1 3.97Å
124F92.6Very high90.5Very high38 Ų3853.1 Ų53.117%0.16727%0.27CS..G310 helixtrans-78-14.6178.6-62.3-25.2000114.2Y120 S121 R122 S126 C209 H245 Q246Y120-F124 AromaticContact CD1-CD2 3.61Å; Y120-F124 HydrophobicContact CD1-CD2 3.61Å; Y120-F124 AromaticContact CD1-CE2 3.65Å; Y120-F124 HydrophobicContact CD1-CE2 3.65Å; Y120-F124 HydrophobicContact CG-CD2 4.39Å; Y120-F124 HydrophobicContact CG-CE2 4.49Å; S121-F124 WeakPolarHBondContact O-CB 3.39Å; S121-F124 WeakPolarHBondContact O-CG 3.47Å; S121-F124 PolarHBondContact O-N 3.39Å; R122-F124 PolarHBondContact O-N 3.18Å; F124-S126 PolarHBondContact O-N 2.93Å; F124-C209 HydrophobicContact CB-CB 4.25Å; F124-H245 HydrophobicContact CB-CB 4.16Å; F124-H245 AromaticContact CD1-CD2 3.83Å; F124-H245 AromaticContact CE1-CD2 3.98Å; F124-H245 HydrophobicContact CG-CB 4.43Å; F124-H245 AromaticContact CG-CD2 3.85Å; F124-Q246 VanDerWaalsContact CA-O 3.26Å; F124-Q246 WeakPolarHBondContact CA-O 3.46Å; F124-Q246 WeakPolarHBondContact CD1-O 3.29Å; F124-Q246 WeakPolarHBondContact O-CB 3.38Å; F124-Q246 PolarHBondContact O-N 3.43Å
125Q90.5Very high90.8Very high20 Ų2046.7 Ų46.79%0.09324%0.236CC..  trans59.1-49.9173.6-58.1-168.6-44.400116.5R122 W123 G207 S208 C209 T251R122-Q125 PolarHBondContact O-N 3.06Å; W123-Q125 VanDerWaalsContact C-N 3.3Å; Q125-G207 CarbonylContact O-C 3.59Å; Q125-S208 CarbonylContact O-C 3.53Å; Q125-S208 WeakPolarHBondContact O-CA 2.96Å; Q125-S208 PolarHBondContact O-N 3.31Å; Q125-C209 PolarHBondContact O-N 3.03Å; Q125-C209 VanDerWaalsContact O-N 3.13Å; Q125-T251 HydrophobicContact CG-CG2 3.79Å; Q125-T251 VanDerWaalsContact NE2-CG2 3.34Å
126S91.6Very high91.3Very high29 Ų2939.5 Ų39.520%0.20320%0.196CC..  trans-135.9156.2179.658.70000111.3F124 L206F124-S126 PolarHBondContact O-N 2.93Å; S126-L206 VanDerWaalsContact CA-O 3.24Å; S126-L206 WeakPolarHBondContact CA-O 3.49Å; S126-L206 WeakPolarHBondContact CB-O 3.5Å
127L92.7Very high91.4Very high0 Ų037.6 Ų37.60%018%0.18CC..EExtended strand (participates in β ladder)trans-134.6119.7177.8-16476.2000109.3Y120 F204 L206 Y214 E243 H245Y120-L127 HydrophobicContact CD1-CD1 4.48Å; Y120-L127 HydrophobicContact CE1-CD1 3.98Å; L127-F204 HydrophobicContact CB-CE2 4.44Å; L127-F204 HydrophobicContact CD2-CE2 3.87Å; L127-F204 HydrophobicContact CD2-CZ 4.18Å; L127-F204 HydrophobicContact CG-CE2 4.02Å; L127-F204 HydrophobicContact CG-CZ 4.49Å; L127-L206 HydrophobicContact CB-CB 4.1Å; L127-L206 HydrophobicContact CB-CD1 4.21Å; L127-L206 HydrophobicContact CB-CG 4.49Å; L127-L206 HydrophobicContact CD2-CD1 4.02Å; L127-L206 PolarHBondContact N-O 3.49Å; L127-L206 PolarHBondContact O-N 3.25Å; L127-Y214 HydrophobicContact CD2-CD2 4.14Å; L127-Y214 HydrophobicContact CD2-CE2 4.26Å; L127-E243 HydrophobicContact CD1-CG 3.51Å; L127-E243 WeakPolarHBondContact CD1-OE1 3.24Å; L127-E243 HydrophobicContact CD2-CG 4.49Å; L127-E243 HydrophobicContact CG-CG 3.97Å; L127-H245 HydrophobicContact CD1-CB 4.05Å
128L92.6Very high91.3Very high49 Ų4935 Ų3526%0.25717%0.17SC..EExtended strand (participates in β ladder)trans-112132.8176.8175.571.7000109L130 E205 E243 I244L128-L130 HydrophobicContact CD2-CD2 4.39Å; L128-L130 HydrophobicContact CG-CD2 4.38Å; L128-E205 HydrophobicContact CD1-CB 3.99Å; L128-E205 HydrophobicContact CD1-CG 4.17Å; L128-E243 CarbonylContact O-C 3.55Å; L128-E243 VanDerWaalsContact O-CA 3.32Å; L128-E243 WeakPolarHBondContact O-CA 3.46Å; L128-I244 HydrophobicContact CB-CB 4.3Å; L128-I244 HydrophobicContact CD2-CD1 4.26Å; L128-I244 PolarHBondContact N-O 2.93Å; L128-I244 PolarHBondContact O-N 3.42Å
129G92.9Very high90.8Very high0 Ų039.1 Ų39.10%019%0.187CC..EExtended strand (participates in β ladder)trans-115.4123.6175.400000111.5L203 F204G129-L203 WeakPolarHBondContact O-CA 3.49Å; G129-L203 WeakPolarHBondContact O-CB 3.3Å; G129-L203 PolarHBondContact O-N 3Å; G129-F204 PolarHBondContact N-O 3.38Å; G129-F204 PolarHBondContact O-N 3.41Å
130L93.7Very high90.3Very high31 Ų3138.4 Ų38.416%0.16219%0.186CC..EExtended strand (participates in β ladder)trans-107.3126.6172.1-56.2179.1000109.3L128 I201 E202 I241 I242 I244L128-L130 HydrophobicContact CD2-CD2 4.39Å; L128-L130 HydrophobicContact CG-CD2 4.38Å; L130-I201 CarbonylContact C-O 3.47Å; L130-I201 WeakPolarHBondContact CA-O 3.48Å; L130-E202 HydrophobicContact CD2-CB 4.45Å; L130-E202 HydrophobicContact CD2-CG 3.87Å; L130-I241 CarbonylContact O-C 3.5Å; L130-I241 VanDerWaalsContact O-CA 3.32Å; L130-I241 WeakPolarHBondContact O-CA 3.48Å; L130-I242 HydrophobicContact CB-CB 4.37Å; L130-I242 PolarHBondContact N-O 3.4Å; L130-I242 PolarHBondContact O-N 3.4Å; L130-I244 HydrophobicContact CD1-CD1 3.92Å
131L94.1Very high89.7Confident0 Ų043.3 Ų43.30%022%0.219CC..EExtended strand (participates in β ladder)trans-92.5121.6175.1-17870.1000109.9M55 I133 L153 I201 L203 I218 L239 I241M55-L131 HydrophobicContact SD-CD1 4.22Å; L131-I133 HydrophobicContact CD2-CD1 3.92Å; L131-I133 HydrophobicContact CD2-CG1 4.07Å; L131-I133 HydrophobicContact CG-CD1 4.36Å; L131-I133 HydrophobicContact CG-CG1 3.96Å; L131-L153 HydrophobicContact CD2-CD1 3.57Å; L131-I201 HydrophobicContact CB-CB 4.34Å; L131-I201 PolarHBondContact N-O 3.29Å; L131-I201 PolarHBondContact O-N 3.49Å; L131-L203 HydrophobicContact CB-CB 4.17Å; L131-L203 HydrophobicContact CB-CD2 4.38Å; L131-I218 HydrophobicContact CD1-CD1 4.33Å; L131-L239 HydrophobicContact CD1-CB 4.36Å; L131-L239 HydrophobicContact CD1-CD2 4.41Å; L131-I241 HydrophobicContact CD1-CD1 4.27Å; L131-I241 HydrophobicContact CD1-CG1 3.74Å
132L93Very high89Confident45 Ų4548.4 Ų48.424%0.23624%0.237CC..EExtended strand (participates in β ladder)trans-101.8127.7169.8-69.3176000108.7P200 N240 I242L132-P200 HydrophobicContact CD2-CB 3.73Å; L132-N240 HydrophobicContact CB-CB 3.91Å; L132-N240 HydrophobicContact CD1-CB 4.48Å; L132-N240 PolarHBondContact N-O 3.07Å; L132-N240 PolarHBondContact O-N 2.9Å; L132-I242 HydrophobicContact CD1-CD1 3.44Å; L132-I242 VanDerWaalsContact CD1-CD1 3.44Å; L132-I242 HydrophobicContact CD1-CG1 3.83Å; L132-I242 HydrophobicContact CG-CD1 4.29Å
133I91.5Very high88.4Confident10 Ų1048.3 Ų48.35%0.05124%0.237CC..EExtended strand (participates in β ladder)trans-114.8119.8-177.6-54.3-169.9000108L131 T135 L151 L181 I201 L236 L239L131-I133 HydrophobicContact CD2-CD1 3.92Å; L131-I133 HydrophobicContact CD2-CG1 4.07Å; L131-I133 HydrophobicContact CG-CD1 4.36Å; L131-I133 HydrophobicContact CG-CG1 3.96Å; I133-T135 HydrophobicContact CG2-CG2 3.88Å; I133-L151 HydrophobicContact CD1-CD2 3.05Å; I133-L151 HydrophobicContact CD1-CG 4.5Å; I133-L181 HydrophobicContact CB-CD1 4.27Å; I133-L181 HydrophobicContact CD1-CD1 4.14Å; I133-I201 HydrophobicContact CD1-CD1 3.78Å; I133-I201 HydrophobicContact CG1-CD1 4.42Å; I133-L236 HydrophobicContact CG2-CD1 3.49Å; I133-L236 VanDerWaalsContact CG2-CD1 3.49Å; I133-L239 HydrophobicContact CB-CD2 4.14Å; I133-L239 HydrophobicContact CD1-CD2 4.28Å; I133-L239 HydrophobicContact CG1-CD2 3.77Å; I133-L239 HydrophobicContact CG2-CD2 3.87Å
134E90.1Very high88Confident64 Ų6451.4 Ų51.430%0.29925%0.253SS..EExtended strand (participates in β ladder)trans-98.7120.5176.9-65.1-173.4-168.400109T237 E238 N240E134-T237 PolarHBondContact O-N 2.93Å; E134-T237 PolarHBondContact O-OG1 3.48Å; E134-T237 VanDerWaalsContact O-OG1 3.09Å; E134-E238 HydrophobicContact CB-CB 4.39Å; E134-E238 PolarHBondContact N-O 2.94Å; E134-N240 PolarHBondContact OE1-ND2 3.01Å
135T89.3Confident87.7Confident1 Ų151 Ų511%0.00625%0.251CS..EExtended strand (participates in β ladder)trans-124.5131178.759.80000109.1I133 H195 F196 I233 R235 L236I133-T135 HydrophobicContact CG2-CG2 3.88Å; T135-H195 CarbonylContact O-C 3.59Å; T135-H195 VanDerWaalsContact O-CA 3.25Å; T135-H195 WeakPolarHBondContact O-CA 3.38Å; T135-F196 PolarHBondContact O-N 3.48Å; T135-F196 WeakPolarHBondContact OG1-CB 3.34Å; T135-F196 WeakPolarHBondContact OG1-CD2 3.47Å; T135-I233 WeakPolarHBondContact CG2-O 3.49Å; T135-R235 CarbonylContact C-O 3.53Å; T135-R235 WeakPolarHBondContact CA-O 3.4Å; T135-L236 HydrophobicContact CG2-CD1 4.48Å
136E88.2Confident87.4Confident25 Ų2550.7 Ų50.712%0.11725%0.254CS..EExtended strand (participates in β ladder)trans-86.4141.4178-169.9-169.3176.700110.2S138 G193 R235 T237E136-S138 PolarHBondContact O-N 3.43Å; E136-G193 VanDerWaalsContact OE1-CA 3.28Å; E136-G193 WeakPolarHBondContact OE1-CA 3.23Å; E136-G193 PolarHBondContact OE1-N 3.03Å; E136-R235 PolarHBondContact N-O 3.36Å; E136-R235 WeakPolarHBondContact OE2-CD 3.49Å; E136-R235 IonicContact OE2-NE 3.91Å; E136-R235 PolarHBondContact OE2-NE 2.91Å; E136-R235 VanDerWaalsContact OE2-NE 3.07Å; E136-T237 HydrophobicContact CB-CG2 3.69Å
137Y85.9Confident87.1Confident50 Ų5058.8 Ų58.820%0.19629%0.286CS..  trans-67.4127.4170.2-178.7-91.1000110.7E139 I185 R190 F194 F196Y137-E139 HydrophobicContact CE1-CG 3.88Å; Y137-I185 HydrophobicContact CD2-CD1 4.02Å; Y137-I185 HydrophobicContact CG-CD1 4.12Å; Y137-R190 HydrophobicContact CE1-CB 4.42Å; Y137-R190 HydrophobicContact CE2-CB 4.11Å; Y137-R190 HydrophobicContact CE2-CG 4.19Å; Y137-F194 WeakPolarHBondContact CB-O 3.46Å; Y137-F194 PolarHBondContact N-O 3.31Å; Y137-F196 HydrophobicContact CD2-CE2 4.1Å; Y137-F196 AromaticContact CD2-CZ 3.72Å; Y137-F196 HydrophobicContact CD2-CZ 3.72Å
138S83.3Confident86.7Confident21 Ų2162.7 Ų62.715%0.14731%0.306CS..  trans-134.8137.1174.6-171.80000110.6E136 N140E136-S138 PolarHBondContact O-N 3.43Å; S138-N140 PolarHBondContact OG-N 2.9Å
139E79.7Confident86.6Confident145 Ų14561 Ų6168%0.67830%0.298SS*.  trans-76.9-12.4173.5-63.5-173171.100112.7Y137Y137-E139 HydrophobicContact CE1-CG 3.88Å
140N80.9Confident86.4Confident60 Ų6066 Ų6632%0.32132%0.322SS..SBendtrans-66.1125.2179.2-179.7-11000109.5S138 Q142 W143 K144S138-N140 PolarHBondContact OG-N 2.9Å; N140-Q142 PolarHBondContact O-N 3.15Å; N140-Q142 WeakPolarHBondContact OD1-CB 3.18Å; N140-Q142 PolarHBondContact OD1-N 2.8Å; N140-W143 PolarHBondContact O-N 3.1Å; N140-K144 PolarHBondContact O-N 3.27Å
141P80.8Confident86.3Confident111 Ų11164.7 Ų64.772%0.72132%0.315SS*.G310 helixtrans-57.8-23.8-178.722.4-34.7000113.9W143P141-W143 VanDerWaalsContact C-N 3.29Å; P141-W143 PolarHBondContact O-N 2.7Å
142Q77.8Confident86.2Confident152 Ų15268 Ų6871%0.7133%0.327SS*.G310 helixtrans-67-30.2175.2-67.3-178.6-31.800113.1N140N140-Q142 PolarHBondContact O-N 3.15Å; N140-Q142 WeakPolarHBondContact OD1-CB 3.18Å; N140-Q142 PolarHBondContact OD1-N 2.8Å
143W81Confident86.3Confident89 Ų8965.9 Ų65.934%0.33732%0.316SS..G310 helixtrans-108.219.6-176.4-56.2118.8000112.2N140 P141 M145 G234 R235N140-W143 PolarHBondContact O-N 3.1Å; P141-W143 VanDerWaalsContact C-N 3.29Å; P141-W143 PolarHBondContact O-N 2.7Å; W143-M145 PolarHBondContact O-N 3.39Å; W143-G234 WeakPolarHBondContact O-CA 3.26Å; W143-R235 HydrophobicContact CB-CB 4.05Å; W143-R235 HydrophobicContact CD2-CB 4.23Å; W143-R235 HydrophobicContact CE3-CB 4.29Å; W143-R235 HydrophobicContact CG-CB 4.13Å
144K85.1Confident86.4Confident140 Ų14067.1 Ų67.161%0.60932%0.322SS*.  trans-68.3125.9180-174.8179.6178.7-175.90109.9N140 E232N140-K144 PolarHBondContact O-N 3.27Å; K144-E232 CarbonylContact O-C 3.13Å; K144-E232 WeakPolarHBondContact O-CA 3.41Å; K144-E232 WeakPolarHBondContact O-CB 3.4Å
145M86.5Confident86.7Confident28 Ų2864.1 Ų64.114%0.13831%0.308CS..BIsolated β-bridgetrans-74.4127.9173.3-173.360176.400110.9W143 P149 L181 C183 F196 E232W143-M145 PolarHBondContact O-N 3.39Å; M145-P149 HydrophobicContact CE-CG 3.46Å; M145-P149 VanDerWaalsContact CE-CG 3.46Å; M145-P149 HydrophobicContact SD-CG 3.77Å; M145-L181 HydrophobicContact CE-CB 4.37Å; M145-L181 HydrophobicContact CE-CD2 3.64Å; M145-L181 HydrophobicContact CE-CG 3.72Å; M145-L181 HydrophobicContact SD-CD2 4.43Å; M145-C183 HydrophobicContact CE-CB 3.87Å; M145-F196 HydrophobicContact CB-CE1 4.03Å; M145-F196 HydrophobicContact CB-CE2 3.95Å; M145-F196 HydrophobicContact CB-CZ 3.56Å; M145-F196 HydrophobicContact CG-CE1 4.17Å; M145-F196 HydrophobicContact CG-CE2 4.49Å; M145-F196 HydrophobicContact CG-CZ 4.15Å; M145-E232 CarbonylContact C-O 3.3Å; M145-E232 WeakPolarHBondContact CA-O 3.13Å
146G85.8Confident87Confident14 Ų1465.6 Ų65.614%0.14431%0.313CS..  trans-79.4174.2178.100000111.9N148 E232G146-N148 PolarHBondContact O-N 3.42Å; G146-E232 WeakPolarHBondContact CA-OE2 3.33Å; G146-E232 PolarHBondContact N-O 3.19Å
147K84.4Confident87.4Confident200 Ų20064.4 Ų64.487%0.8731%0.308SS*.SBendtrans-84.5100.4172-171.9179-179.4-178.90109.1
148N84.5Confident87.8Confident81 Ų8162 Ų6243%0.43330%0.298SS..SBendtrans55.160.9-176.5-58-24.8000113.2G146 L181G146-N148 PolarHBondContact O-N 3.42Å; N148-L181 WeakPolarHBondContact CA-O 3.36Å
149P89.8Confident88.3Confident13 Ų1363.1 Ų63.18%0.08430%0.299CS..  trans-63.7147.9-179.529.5-36.3000111.5M145 L151 L181 E232 I233M145-P149 HydrophobicContact CE-CG 3.46Å; M145-P149 VanDerWaalsContact CE-CG 3.46Å; M145-P149 HydrophobicContact SD-CG 3.77Å; P149-L151 PolarHBondContact O-N 2.92Å; P149-L181 WeakPolarHBondContact CD-O 3.35Å; P149-L181 HydrophobicContact CG-CB 4.19Å; P149-L181 HydrophobicContact CG-CD2 4.48Å; P149-L181 PolarHBondContact O-N 2.98Å; P149-E232 WeakPolarHBondContact CG-O 3.34Å; P149-I233 HydrophobicContact CB-CG2 4.12Å; P149-I233 HydrophobicContact CG-CG2 4.24Å
150E89.1Confident89Confident106 Ų10657.8 Ų57.850%0.49527%0.273SS..EExtended strand (participates in β ladder)trans-79.7118.3173-174.7-176.617200109.4S178 M180E150-S178 WeakPolarHBondContact OE1-CB 3.27Å; E150-S178 PolarHBondContact OE1-OG 3.46Å; E150-M180 HydrophobicContact CB-CE 4.46Å; E150-M180 HydrophobicContact CB-SD 4.23Å
151L91.6Very high89.6Confident3 Ų357.6 Ų57.62%0.01627%0.272CS..EExtended strand (participates in β ladder)trans-97.4112.4173.2-178.973.1000109.8I133 P149 L153 S178 R179 L181 I201 I220 N230 I233I133-L151 HydrophobicContact CD1-CD2 3.05Å; I133-L151 HydrophobicContact CD1-CG 4.5Å; P149-L151 PolarHBondContact O-N 2.92Å; L151-L153 HydrophobicContact CD1-CD2 4.1Å; L151-L153 HydrophobicContact CD2-CD1 4.15Å; L151-L153 HydrophobicContact CD2-CD2 3.86Å; L151-L153 HydrophobicContact CD2-CG 4.09Å; L151-L153 HydrophobicContact CG-CD2 3.8Å; L151-L153 HydrophobicContact CG-CG 4.04Å; L151-S178 CarbonylContact O-C 3.53Å; L151-S178 WeakPolarHBondContact O-CA 3.39Å; L151-R179 PolarHBondContact N-O 2.67Å; L151-R179 PolarHBondContact O-N 3.27Å; L151-L181 HydrophobicContact CB-CB 4.46Å; L151-I201 HydrophobicContact CD2-CD1 4.3Å; L151-I220 HydrophobicContact CD1-CG2 4.25Å; L151-N230 WeakPolarHBondContact CA-OD1 3.44Å; L151-I233 HydrophobicContact CD1-CD1 4.07Å; L151-I233 HydrophobicContact CD1-CG2 4.23Å
152R92.9Very high90Very high71 Ų7160 Ų6027%0.26827%0.267SS..EExtended strand (participates in β ladder)trans-93.9125.5172.2-171.3173.8-177.7152.36.9109.9I177 P221 N230R152-I177 CarbonylContact C-O 3.52Å; R152-I177 WeakPolarHBondContact CA-O 3.5Å; R152-P221 HydrophobicContact CG-CG 4.33Å; R152-P221 WeakPolarHBondContact O-CD 3.4Å; R152-N230 PolarHBondContact N-OD1 3.48Å; R152-N230 PolarHBondContact O-ND2 3.08Å; R152-N230 PolarHBondContact O-OD1 3.05Å
153L93.9Very high90.5Very high0 Ų060.2 Ų60.20%027%0.273CS..EExtended strand (participates in β ladder)trans-120.6136179.8-56.7174.3000109.8L131 L151 V155 T176 I177 L203 I218 I220L131-L153 HydrophobicContact CD2-CD1 3.57Å; L151-L153 HydrophobicContact CD1-CD2 4.1Å; L151-L153 HydrophobicContact CD2-CD1 4.15Å; L151-L153 HydrophobicContact CD2-CD2 3.86Å; L151-L153 HydrophobicContact CD2-CG 4.09Å; L151-L153 HydrophobicContact CG-CD2 3.8Å; L151-L153 HydrophobicContact CG-CG 4.04Å; L153-V155 HydrophobicContact CB-CG1 3.9Å; L153-T176 CarbonylContact O-C 3.43Å; L153-T176 WeakPolarHBondContact O-CA 3.24Å; L153-I177 HydrophobicContact CB-CD1 4.35Å; L153-I177 HydrophobicContact CB-CG1 3.82Å; L153-I177 HydrophobicContact CD1-CD1 4.25Å; L153-I177 HydrophobicContact CD1-CG1 4.48Å; L153-I177 PolarHBondContact N-O 3.23Å; L153-I177 PolarHBondContact O-N 3.47Å; L153-L203 HydrophobicContact CD1-CD1 4.33Å; L153-I218 HydrophobicContact CB-CG2 4.21Å; L153-I218 HydrophobicContact CD2-CG2 3.96Å; L153-I218 HydrophobicContact CG-CG2 4.48Å; L153-I220 HydrophobicContact CD2-CD1 4.13Å; L153-I220 HydrophobicContact CD2-CG1 3.71Å
154E94.5Very high91Very high36 Ų3657.6 Ų57.617%0.16827%0.265CS..EExtended strand (participates in β ladder)trans-98.8108.1167.7-57.7-179.5177.100107.5R101 T176 I218 R219 P221R101-E154 IonicContact CZ-OE1 3.53Å; R101-E154 IonicContact NE-OE1 3.87Å; R101-E154 PolarHBondContact NE-OE1 3.18Å; R101-E154 IonicContact NE-OE2 3.71Å; R101-E154 IonicContact NH2-OE1 2.71Å; R101-E154 PolarHBondContact NH2-OE1 3.22Å; E154-T176 HydrophobicContact CB-CG2 4.39Å; E154-T176 HydrophobicContact CG-CG2 3.83Å; E154-I218 CarbonylContact O-C 3.55Å; E154-I218 WeakPolarHBondContact O-CA 3.26Å; E154-R219 HydrophobicContact CB-CB 4.21Å; E154-R219 PolarHBondContact N-O 3.2Å; E154-R219 PolarHBondContact O-N 3.47Å; E154-P221 HydrophobicContact CG-CG 4.08Å
155V95.5Very high91.2Very high1 Ų154.2 Ų54.21%0.00626%0.258CS..EExtended strand (participates in β ladder)trans-112.4132.5-170.9-61.20000110.2L153 T175 I177 L203 I218 F385L153-V155 HydrophobicContact CB-CG1 3.9Å; V155-T175 HydrophobicContact CG2-CG2 3.66Å; V155-T175 WeakPolarHBondContact CG2-O 3.31Å; V155-T175 PolarHBondContact N-O 2.92Å; V155-T175 PolarHBondContact O-N 3.01Å; V155-T175 VanDerWaalsContact O-O 3.08Å; V155-I177 HydrophobicContact CG1-CD1 3.96Å; V155-I177 HydrophobicContact CG1-CG1 4.17Å; V155-I177 HydrophobicContact CG2-CD1 4.25Å; V155-I177 HydrophobicContact CG2-CG1 4.29Å; V155-I177 HydrophobicContact CG2-CG2 4.28Å; V155-L203 HydrophobicContact CG1-CD1 4.24Å; V155-I218 HydrophobicContact CG1-CD1 4.48Å; V155-I218 HydrophobicContact CG1-CG1 4.11Å; V155-I218 HydrophobicContact CG1-CG2 4.27Å; V155-F385 HydrophobicContact CB-CD1 4.27Å; V155-F385 HydrophobicContact CB-CE1 3.93Å; V155-F385 HydrophobicContact CB-CZ 4.23Å; V155-F385 HydrophobicContact CG1-CE1 4.45Å; V155-F385 HydrophobicContact CG2-CB 4.47Å; V155-F385 HydrophobicContact CG2-CD1 3.63Å; V155-F385 HydrophobicContact CG2-CD2 4.11Å; V155-F385 HydrophobicContact CG2-CE1 3.74Å; V155-F385 HydrophobicContact CG2-CE2 4.22Å; V155-F385 HydrophobicContact CG2-CG 3.83Å; V155-F385 HydrophobicContact CG2-CZ 4.03Å
156R95.5Very high91Very high32 Ų3255.6 Ų55.612%0.12127%0.269CS..EExtended strand (participates in β ladder)trans-128.2123.2174.9-63-175.568.6-159.15.3108.7G67 W69 E171 S174 L216 N217G67-R156 PolarHBondContact O-NH1 3Å; G67-R156 PolarHBondContact O-NH2 3.23Å; W69-R156 HydrophobicContact CH2-CB 3.77Å; W69-R156 HydrophobicContact CZ3-CB 3.75Å; R156-E171 IonicContact CZ-OE2 2.71Å; R156-E171 IonicContact NE-OE2 2.71Å; R156-E171 PolarHBondContact NE-OE2 3.46Å; R156-E171 IonicContact NH2-OE2 3.08Å; R156-E171 PolarHBondContact NH2-OE2 3.35Å; R156-S174 WeakPolarHBondContact CG-OG 3.48Å; R156-L216 WeakPolarHBondContact O-CA 3.4Å; R156-N217 HydrophobicContact CB-CB 4.38Å; R156-N217 PolarHBondContact N-O 3.3Å; R156-N217 PolarHBondContact O-N 3.06Å
157M95.8Very high91Very high0 Ų059.3 Ų59.30%029%0.285CS..EExtended strand (participates in β ladder)trans-109.1125.3173.6-172.9173.1-82.300109.4L172 I173 F204 L206 Y214 L215 L216 F385M157-L172 HydrophobicContact CB-CB 4.49Å; M157-L172 HydrophobicContact CG-CB 4.42Å; M157-L172 HydrophobicContact CG-CD2 4.15Å; M157-L172 WeakPolarHBondContact O-CA 3.31Å; M157-L172 VanDerWaalsContact O-CB 3.32Å; M157-L172 WeakPolarHBondContact O-CB 3.45Å; M157-L172 PolarHBondContact O-N 3.08Å; M157-L172 HydrophobicContact SD-CD2 3.76Å; M157-I173 HydrophobicContact CB-CG2 4.23Å; M157-I173 PolarHBondContact N-O 2.77Å; M157-I173 PolarHBondContact O-N 2.77Å; M157-F204 HydrophobicContact CE-CD1 3.55Å; M157-F204 HydrophobicContact CE-CD2 3.82Å; M157-F204 HydrophobicContact CE-CE1 3.54Å; M157-F204 HydrophobicContact CE-CE2 3.83Å; M157-F204 HydrophobicContact CE-CG 3.69Å; M157-F204 HydrophobicContact CE-CZ 3.69Å; M157-L206 HydrophobicContact SD-CD1 4.08Å; M157-L206 HydrophobicContact SD-CD2 4.45Å; M157-Y214 HydrophobicContact SD-CD1 4.33Å; M157-L215 CarbonylContact C-O 3.58Å; M157-L215 WeakPolarHBondContact CA-O 3.46Å; M157-L216 HydrophobicContact CE-CD1 4.39Å; M157-F385 HydrophobicContact CB-CE2 4.08Å; M157-F385 HydrophobicContact CB-CZ 3.97Å; M157-F385 HydrophobicContact CE-CZ 3.96Å
158G95.2Very high91.3Very high0 Ų051.2 Ų51.20%026%0.256CS..EExtended strand (participates in β ladder)trans-112.8160.9171.700000111.4H170 Y214 L215G158-H170 CarbonylContact C-O 3.58Å; G158-H170 WeakPolarHBondContact CA-O 3.45Å; G158-Y214 WeakPolarHBondContact O-CA 3.43Å; G158-L215 PolarHBondContact N-O 3.43Å; G158-L215 PolarHBondContact O-N 3.18Å
159Y95Very high91.7Very high43 Ų4348 Ų4817%0.16924%0.238CC..EExtended strand (participates in β ladder)trans-130.3160.1172.371.2-92.7000110.5H170 L172 Y211 F213Y159-H170 HydrophobicContact CD1-CB 4.08Å; Y159-H170 WeakPolarHBondContact CD1-O 3.47Å; Y159-H170 HydrophobicContact CD2-CB 4.16Å; Y159-H170 HydrophobicContact CE1-CB 3.63Å; Y159-H170 HydrophobicContact CE2-CB 3.7Å; Y159-H170 HydrophobicContact CG-CB 4.34Å; Y159-H170 VanDerWaalsContact CZ-CB 3.42Å; Y159-H170 PolarHBondContact N-O 3.41Å; Y159-H170 PolarHBondContact O-N 3.49Å; Y159-L172 HydrophobicContact CD1-CB 4.07Å; Y159-L172 HydrophobicContact CD1-CD1 4.12Å; Y159-L172 HydrophobicContact CE1-CD1 4.4Å; Y159-Y211 HydrophobicContact CD1-CD2 4.21Å; Y159-Y211 HydrophobicContact CD1-CE1 4.42Å; Y159-Y211 AromaticContact CD1-CE2 3.9Å; Y159-Y211 HydrophobicContact CD1-CE2 3.9Å; Y159-Y211 AromaticContact CD1-CZ 3.99Å; Y159-Y211 AromaticContact CD2-CD1 3.24Å; Y159-Y211 HydrophobicContact CD2-CD1 3.24Å; Y159-Y211 HydrophobicContact CD2-CD2 4.01Å; Y159-Y211 AromaticContact CD2-CE1 3.31Å; Y159-Y211 HydrophobicContact CD2-CE1 3.31Å; Y159-Y211 HydrophobicContact CD2-CE2 4.08Å; Y159-Y211 AromaticContact CD2-CG 3.6Å; Y159-Y211 HydrophobicContact CD2-CG 3.6Å; Y159-Y211 AromaticContact CD2-CZ 3.74Å; Y159-Y211 HydrophobicContact CE1-CE1 4.36Å; Y159-Y211 HydrophobicContact CE1-CE2 4.23Å; Y159-Y211 AromaticContact CE1-CZ 3.91Å; Y159-Y211 AromaticContact CE2-CD1 3.69Å; Y159-Y211 HydrophobicContact CE2-CD1 3.69Å; Y159-Y211 AromaticContact CE2-CE1 3.26Å; Y159-Y211 HydrophobicContact CE2-CE1 3.26Å; Y159-Y211 HydrophobicContact CE2-CE2 4.43Å; Y159-Y211 HydrophobicContact CE2-CG 4.41Å; Y159-Y211 AromaticContact CE2-CZ 3.68Å; Y159-Y211 AromaticContact CG-CD1 3.84Å; Y159-Y211 HydrophobicContact CG-CD1 3.84Å; Y159-Y211 AromaticContact CG-CD2 3.7Å; Y159-Y211 HydrophobicContact CG-CD2 3.7Å; Y159-Y211 AromaticContact CG-CE1 3.93Å; Y159-Y211 HydrophobicContact CG-CE1 3.93Å; Y159-Y211 AromaticContact CG-CE2 3.8Å; Y159-Y211 HydrophobicContact CG-CE2 3.8Å; Y159-Y211 AromaticContact CG-CG 3.72Å; Y159-Y211 HydrophobicContact CG-CG 3.72Å; Y159-Y211 AromaticContact CG-CZ 3.9Å; Y159-Y211 AromaticContact CZ-CE1 3.81Å; Y159-Y211 AromaticContact CZ-CZ 3.75Å; Y159-F213 WeakPolarHBondContact CA-O 3.38Å
160R94.1Very high91.9Very high33 Ų3351.1 Ų51.113%0.12525%0.251CS..EExtended strand (participates in β ladder)trans-139.8137.4174-170.8-179.966.984.42.1109.7D164 P165 W169 P212 F213R160-D164 HydrophobicContact CG-CB 3.61Å; R160-D164 PolarHBondContact NH1-O 3.24Å; R160-P165 WeakPolarHBondContact CD-O 3.28Å; R160-W169 HydrophobicContact CB-CD2 4.26Å; R160-W169 HydrophobicContact CB-CE3 3.74Å; R160-W169 HydrophobicContact CB-CH2 4.2Å; R160-W169 HydrophobicContact CB-CZ3 3.69Å; R160-P212 WeakPolarHBondContact O-CD 3.38Å; R160-P212 WeakPolarHBondContact O-CG 3.25Å; R160-F213 HydrophobicContact CB-CB 4.22Å; R160-F213 HydrophobicContact CB-CD2 4.5Å; R160-F213 PolarHBondContact N-O 3.23Å; R160-F213 VanDerWaalsContact N-O 3.12Å
161N92.8Very high92.2Very high56 Ų5650.8 Ų50.830%0.29925%0.249SC..  trans-84.5173.5173.1-59.2-67.6000111.4D163 D164 Y211N161-D163 VanDerWaalsContact C-N 3.31Å; N161-D163 PolarHBondContact O-N 3.46Å; N161-D164 WeakPolarHBondContact CA-OD2 3.29Å; N161-D164 WeakPolarHBondContact CB-OD2 3.39Å; N161-D164 PolarHBondContact N-OD2 2.92Å; N161-D164 PolarHBondContact ND2-OD2 2.91Å; N161-D164 PolarHBondContact O-N 3.46Å; N161-Y211 WeakPolarHBondContact OD1-CD1 3.34Å
162R89Confident92.2Very high162 Ų16252.6 Ų52.661%0.61126%0.259SS*.SBendtrans-64.1-37.1176.8-67.5-177171.8170.2-4.9112.8E119 P212E119-R162 IonicContact OE1-NE 3.93Å; E119-R162 IonicContact OE2-CZ 3.17Å; E119-R162 IonicContact OE2-NE 2.64Å; E119-R162 PolarHBondContact OE2-NE 2.94Å; E119-R162 IonicContact OE2-NH2 3.19Å; E119-R162 PolarHBondContact OE2-NH2 3.23Å; R162-P212 HydrophobicContact CG-CB 4.46Å; R162-P212 HydrophobicContact CG-CG 4.03Å
163D89.3Confident92.3Very high156 Ų15650.6 Ų50.683%0.83425%0.253SS*.SBendtrans-85.7-12-175.1-53.5-49000112.9N161N161-D163 VanDerWaalsContact C-N 3.31Å; N161-D163 PolarHBondContact O-N 3.46Å
164D90.4Very high92.3Very high34 Ų3453.6 Ų53.618%0.18227%0.274CS..SBendtrans-75.9137.7-179.6-63.9-25.8000110R160 N161 A168 H170R160-D164 HydrophobicContact CG-CB 3.61Å; R160-D164 PolarHBondContact NH1-O 3.24Å; N161-D164 WeakPolarHBondContact CA-OD2 3.29Å; N161-D164 WeakPolarHBondContact CB-OD2 3.39Å; N161-D164 PolarHBondContact N-OD2 2.92Å; N161-D164 PolarHBondContact ND2-OD2 2.91Å; N161-D164 PolarHBondContact O-N 3.46Å; D164-A168 HydrophobicContact CB-CB 4.43Å; D164-H170 IonicContact OD1-NE2 2.75Å; D164-H170 IonicContact OD2-CD2 3.51Å; D164-H170 PolarHBondContact OD2-CD2 3.01Å; D164-H170 IonicContact OD2-NE2 3.25Å
165P88.9Confident92.3Very high70 Ų7053.6 Ų53.646%0.45528%0.276SS..  trans-61.9156.3175.828.9-34.8000110.4R160 D167 A168R160-P165 WeakPolarHBondContact CD-O 3.28Å; P165-D167 WeakPolarHBondContact CB-OD1 3.24Å; P165-D167 PolarHBondContact O-N 3.27Å; P165-A168 HydrophobicContact CG-CB 3.59Å; P165-A168 PolarHBondContact O-N 2.88Å
166P84Confident92.2Very high57 Ų5757 Ų5737%0.3730%0.297SS..THydrogen-bonded Turntrans-59.1-24.5-168.420-31.9000115.2P74 W169P74-P166 VanDerWaalsContact CD-CB 3.44Å; P74-P166 HydrophobicContact CG-CB 3.68Å; P74-P166 HydrophobicContact CG-CG 4.1Å; P166-W169 PolarHBondContact O-NE1 3.48Å
167D85.5Confident92.1Very high91 Ų9155.9 Ų55.949%0.48729%0.294SS..THydrogen-bonded Turntrans-90.7-17.9-179.861.2-38.9000113.8Y71 P165 W169Y71-D167 HydrophobicContact CE1-CB 4.32Å; Y71-D167 WeakPolarHBondContact OH-CB 3.5Å; P165-D167 WeakPolarHBondContact CB-OD1 3.24Å; P165-D167 PolarHBondContact O-N 3.27Å; D167-W169 PolarHBondContact O-N 3.42Å
168A90Very high91.9Very high30 Ų3057.7 Ų57.725%0.24831%0.306CS..  trans-82.877.7-175.800000112.7D164 P165D164-A168 HydrophobicContact CB-CB 4.43Å; P165-A168 HydrophobicContact CG-CB 3.59Å; P165-A168 PolarHBondContact O-N 2.88Å
169W93Very high91.7Very high14 Ų1458.5 Ų58.55%0.05331%0.309CS..PPolyproline II helixtrans-84.8125.2171.5-67.493.8000111.8W69 Y71 Q108 R160 P166 D167 F213 L215W69-W169 HydrophobicContact CB-CB 4.12Å; W69-W169 HydrophobicContact CB-CG 4.41Å; W69-W169 HydrophobicContact CD2-CB 4.09Å; W69-W169 HydrophobicContact CG-CB 3.7Å; W69-W169 HydrophobicContact CG-CG 4.44Å; W69-W169 PolarHBondContact NE1-O 3.24Å; Y71-W169 AromaticContact CD1-CD1 3.74Å; Y71-W169 AromaticContact CD1-NE1 3.64Å; Y71-W169 AromaticContact CG-NE1 3.61Å; Q108-W169 HydrophobicContact CG-CH2 4.22Å; Q108-W169 HydrophobicContact CG-CZ2 4.23Å; R160-W169 HydrophobicContact CB-CD2 4.26Å; R160-W169 HydrophobicContact CB-CE3 3.74Å; R160-W169 HydrophobicContact CB-CH2 4.2Å; R160-W169 HydrophobicContact CB-CZ3 3.69Å; P166-W169 PolarHBondContact O-NE1 3.48Å; D167-W169 PolarHBondContact O-N 3.42Å; W169-F213 HydrophobicContact CH2-CB 4.01Å; W169-F213 HydrophobicContact CZ3-CB 4.14Å; W169-L215 HydrophobicContact CB-CD2 4.38Å; W169-L215 HydrophobicContact CD2-CB 3.81Å; W169-L215 HydrophobicContact CD2-CD2 3.6Å; W169-L215 HydrophobicContact CD2-CG 4.33Å; W169-L215 HydrophobicContact CE3-CB 3.44Å; W169-L215 VanDerWaalsContact CE3-CB 3.44Å; W169-L215 HydrophobicContact CE3-CD2 4.11Å; W169-L215 HydrophobicContact CE3-CG 4.43Å; W169-L215 HydrophobicContact CG-CD2 3.7Å; W169-L215 HydrophobicContact CH2-CB 3.77Å; W169-L215 HydrophobicContact CZ2-CB 4.12Å; W169-L215 HydrophobicContact CZ2-CD2 4.38Å; W169-L215 HydrophobicContact CZ3-CB 3.44Å; W169-L215 VanDerWaalsContact CZ3-CB 3.44Å
170H94.3Very high91.4Very high78 Ų7859.8 Ų59.836%0.36132%0.318SS..EExtended strand (participates in β ladder)trans-93.4134.5175.5-66.6-66000110.9G158 Y159 D164 L172G158-H170 CarbonylContact C-O 3.58Å; G158-H170 WeakPolarHBondContact CA-O 3.45Å; Y159-H170 HydrophobicContact CD1-CB 4.08Å; Y159-H170 WeakPolarHBondContact CD1-O 3.47Å; Y159-H170 HydrophobicContact CD2-CB 4.16Å; Y159-H170 HydrophobicContact CE1-CB 3.63Å; Y159-H170 HydrophobicContact CE2-CB 3.7Å; Y159-H170 HydrophobicContact CG-CB 4.34Å; Y159-H170 VanDerWaalsContact CZ-CB 3.42Å; Y159-H170 PolarHBondContact N-O 3.41Å; Y159-H170 PolarHBondContact O-N 3.49Å; D164-H170 IonicContact OD1-NE2 2.75Å; D164-H170 IonicContact OD2-CD2 3.51Å; D164-H170 PolarHBondContact OD2-CD2 3.01Å; D164-H170 IonicContact OD2-NE2 3.25Å; H170-L172 PolarHBondContact O-N 3.29Å
171E94.2Very high91.2Very high100 Ų10058.3 Ų58.347%0.46731%0.312SS..EExtended strand (participates in β ladder)trans-70.3123.9178.5-168.4164.8107.300111W69 R156W69-E171 HydrophobicContact CH2-CG 4.3Å; W69-E171 HydrophobicContact CZ2-CB 3.77Å; W69-E171 HydrophobicContact CZ2-CG 3.87Å; R156-E171 IonicContact CZ-OE2 2.71Å; R156-E171 IonicContact NE-OE2 2.71Å; R156-E171 PolarHBondContact NE-OE2 3.46Å; R156-E171 IonicContact NH2-OE2 3.08Å; R156-E171 PolarHBondContact NH2-OE2 3.35Å
172L93Very high91Very high41 Ų4161.4 Ų61.422%0.21532%0.32CS..EExtended strand (participates in β ladder)trans-86.2-51.2169.3-171.364.5000110.3M157 Y159 H170 L206 Y211 Y214M157-L172 HydrophobicContact CB-CB 4.49Å; M157-L172 HydrophobicContact CG-CB 4.42Å; M157-L172 HydrophobicContact CG-CD2 4.15Å; M157-L172 WeakPolarHBondContact O-CA 3.31Å; M157-L172 VanDerWaalsContact O-CB 3.32Å; M157-L172 WeakPolarHBondContact O-CB 3.45Å; M157-L172 PolarHBondContact O-N 3.08Å; M157-L172 HydrophobicContact SD-CD2 3.76Å; Y159-L172 HydrophobicContact CD1-CB 4.07Å; Y159-L172 HydrophobicContact CD1-CD1 4.12Å; Y159-L172 HydrophobicContact CE1-CD1 4.4Å; H170-L172 PolarHBondContact O-N 3.29Å; L172-L206 HydrophobicContact CD2-CD2 4.24Å; L172-Y211 HydrophobicContact CD1-CE2 4.14Å; L172-Y214 HydrophobicContact CD2-CE1 4.43Å
173I94Very high91.1Very high29 Ų2955 Ų5515%0.14930%0.299CS..EExtended strand (participates in β ladder)trans-161.9146.9177.8-173.6170.3000110.4M157 N383 P384 F385M157-I173 HydrophobicContact CB-CG2 4.23Å; M157-I173 PolarHBondContact N-O 2.77Å; M157-I173 PolarHBondContact O-N 2.77Å; I173-N383 HydrophobicContact CD1-CB 4.3Å; I173-P384 HydrophobicContact CG2-CG 4.12Å; I173-F385 HydrophobicContact CG2-CD2 3.92Å; I173-F385 HydrophobicContact CG2-CE2 3.5Å; I173-F385 VanDerWaalsContact CG2-CE2 3.5Å
174S94.3Very high91Very high62 Ų6251 Ų5143%0.43428%0.284SS..EExtended strand (participates in β ladder)trans-128.8123.9172.2176.40000108.5R156R156-S174 WeakPolarHBondContact CG-OG 3.48Å
175T94.2Very high90.8Very high36 Ų3650.4 Ų50.422%0.22128%0.28CS..EExtended strand (participates in β ladder)trans-153.6160.3-177.9-1700000112.2V155 I177 F385V155-T175 HydrophobicContact CG2-CG2 3.66Å; V155-T175 WeakPolarHBondContact CG2-O 3.31Å; V155-T175 PolarHBondContact N-O 2.92Å; V155-T175 PolarHBondContact O-N 3.01Å; V155-T175 VanDerWaalsContact O-O 3.08Å; T175-I177 HydrophobicContact CG2-CG2 4.02Å; T175-F385 HydrophobicContact CG2-CB 4.06Å; T175-F385 HydrophobicContact CG2-CD2 3.95Å; T175-F385 HydrophobicContact CG2-CG 4.18Å
176T93.1Very high90.6Very high72 Ų7251.5 Ų51.544%0.44228%0.283SS..EExtended strand (participates in β ladder)trans-107.2123.5172.168.30000109.2L153 E154L153-T176 CarbonylContact O-C 3.43Å; L153-T176 WeakPolarHBondContact O-CA 3.24Å; E154-T176 HydrophobicContact CB-CG2 4.39Å; E154-T176 HydrophobicContact CG-CG2 3.83Å
177I93.3Very high90.5Very high10 Ų1056.4 Ų56.45%0.05130%0.3CS..EExtended strand (participates in β ladder)trans-114152.5179.562.5175.4000110.6R152 L153 V155 T175 L203 F385R152-I177 CarbonylContact C-O 3.52Å; R152-I177 WeakPolarHBondContact CA-O 3.5Å; L153-I177 HydrophobicContact CB-CD1 4.35Å; L153-I177 HydrophobicContact CB-CG1 3.82Å; L153-I177 HydrophobicContact CD1-CD1 4.25Å; L153-I177 HydrophobicContact CD1-CG1 4.48Å; L153-I177 PolarHBondContact N-O 3.23Å; L153-I177 PolarHBondContact O-N 3.47Å; V155-I177 HydrophobicContact CG1-CD1 3.96Å; V155-I177 HydrophobicContact CG1-CG1 4.17Å; V155-I177 HydrophobicContact CG2-CD1 4.25Å; V155-I177 HydrophobicContact CG2-CG1 4.29Å; V155-I177 HydrophobicContact CG2-CG2 4.28Å; T175-I177 HydrophobicContact CG2-CG2 4.02Å; I177-L203 HydrophobicContact CD1-CD1 3.54Å; I177-F385 HydrophobicContact CD1-CD1 4.39Å; I177-F385 HydrophobicContact CG2-CB 3.78Å
178S91.7Very high90.3Very high37 Ų3759.7 Ų59.726%0.25931%0.313SS..EExtended strand (participates in β ladder)trans-118.4141.7168.5-73.30000109E150 L151 S390E150-S178 WeakPolarHBondContact OE1-CB 3.27Å; E150-S178 PolarHBondContact OE1-OG 3.46Å; L151-S178 CarbonylContact O-C 3.53Å; L151-S178 WeakPolarHBondContact O-CA 3.39Å; S178-S390 WeakPolarHBondContact O-CB 3.01Å
179R92Very high89.9Confident17 Ų1760.6 Ų60.66%0.06431%0.314CS..EExtended strand (participates in β ladder)trans-140.1147.4179.6-67.5-68.2-168.3-85.2-1.3109.5L151 I201 E202 F385L151-R179 PolarHBondContact N-O 2.67Å; L151-R179 PolarHBondContact O-N 3.27Å; R179-I201 HydrophobicContact CB-CD1 4.22Å; R179-I201 HydrophobicContact CB-CG2 3.85Å; R179-I201 HydrophobicContact CG-CG2 3.51Å; R179-E202 PolarHBondContact NE-O 2.79Å; R179-E202 VanDerWaalsContact NE-O 3.09Å; R179-E202 PolarHBondContact NH2-O 3.36Å; R179-F385 PolarHBondContact NH2-O 2.94Å
180M89Confident89.2Confident71 Ų7165.9 Ų65.935%0.3533%0.333SS..EExtended strand (participates in β ladder)trans-88.2120.9175.3-66.9-66.3175.400109.1E150 R182E150-M180 HydrophobicContact CB-CE 4.46Å; E150-M180 HydrophobicContact CB-SD 4.23Å; M180-R182 PolarHBondContact O-N 2.85Å
181L89.6Confident88.6Confident1 Ų170.2 Ų70.21%0.00535%0.347CS..  trans-86.9104.7-179.9-178.660.1000109.4I133 M145 N148 P149 L151 C183 C198 I201 I233I133-L181 HydrophobicContact CB-CD1 4.27Å; I133-L181 HydrophobicContact CD1-CD1 4.14Å; M145-L181 HydrophobicContact CE-CB 4.37Å; M145-L181 HydrophobicContact CE-CD2 3.64Å; M145-L181 HydrophobicContact CE-CG 3.72Å; M145-L181 HydrophobicContact SD-CD2 4.43Å; N148-L181 WeakPolarHBondContact CA-O 3.36Å; P149-L181 WeakPolarHBondContact CD-O 3.35Å; P149-L181 HydrophobicContact CG-CB 4.19Å; P149-L181 HydrophobicContact CG-CD2 4.48Å; P149-L181 PolarHBondContact O-N 2.98Å; L151-L181 HydrophobicContact CB-CB 4.46Å; L181-C183 WeakPolarHBondContact CD1-SG 3.38Å; L181-C183 WeakPolarHBondContact CG-SG 3.4Å; L181-C198 HydrophobicContact CD1-CB 4.2Å; L181-I201 HydrophobicContact CD1-CD1 4.17Å; L181-I233 HydrophobicContact CD2-CB 4.32Å
182R89Confident87.7Confident122 Ų12269.2 Ų69.246%0.4635%0.351SS..  trans-97.6105.6178.5-67.5175.9-179.5179.45.4109.2M180 C198 E199M180-R182 PolarHBondContact O-N 2.85Å; R182-C198 WeakPolarHBondContact O-CA 3.27Å; R182-E199 HydrophobicContact CB-CB 4.39Å; R182-E199 HydrophobicContact CB-CG 4.29Å; R182-E199 WeakPolarHBondContact CD-OE2 3.48Å; R182-E199 IonicContact NH1-OE2 2.77Å; R182-E199 PolarHBondContact O-N 3.44Å
183C89.4Confident86.9Confident27 Ų2769.6 Ų69.618%0.18236%0.364CS..EExtended strand (participates in β ladder)trans-128.5143.2178-48.30000111.3M145 L181 F196 Q197 C198M145-C183 HydrophobicContact CE-CB 3.87Å; L181-C183 WeakPolarHBondContact CD1-SG 3.38Å; L181-C183 WeakPolarHBondContact CG-SG 3.4Å; C183-F196 HydrophobicContact CB-CB 3.93Å; C183-F196 HydrophobicContact CB-CD1 4.37Å; C183-F196 HydrophobicContact CB-CG 4.45Å; C183-Q197 WeakPolarHBondContact CA-O 3.47Å; C183-C198 HydrophobicContact CB-CB 4.04Å; C183-C198 WeakPolarHBondContact CB-SG 3.46Å; C183-C198 WeakPolarHBondContact SG-CB 3.49Å; C183-C198 CovalentContact SG-SG 2.03Å; C183-C198 PolarHBondContact SG-SG 3.46Å
184S88Confident86.6Confident73 Ų7372.5 Ų72.551%0.5138%0.376SS..EExtended strand (participates in β ladder)trans-125.7149.6174.649.30000110.4Q197S184-Q197 PolarHBondContact N-O 3.34Å; S184-Q197 PolarHBondContact O-N 2.74Å
185I86.2Confident86.2Confident20 Ų2073.8 Ų73.810%0.10338%0.375CS..  trans-136.1128.7171.1-166.1167.3000108.5Y137 N189 R190 F196Y137-I185 HydrophobicContact CD2-CD1 4.02Å; Y137-I185 HydrophobicContact CG-CD1 4.12Å; I185-N189 HydrophobicContact CD1-CB 4.43Å; I185-N189 VanDerWaalsContact CD1-O 3.32Å; I185-N189 WeakPolarHBondContact CD1-O 3.41Å; I185-N189 HydrophobicContact CG1-CB 4.01Å; I185-R190 HydrophobicContact CG1-CG 4.48Å; I185-R190 HydrophobicContact CG2-CG 3.82Å; I185-F196 HydrophobicContact CB-CD1 3.58Å; I185-F196 HydrophobicContact CB-CE1 3.83Å; I185-F196 HydrophobicContact CB-CG 4.34Å; I185-F196 HydrophobicContact CD1-CD1 4.41Å; I185-F196 HydrophobicContact CD1-CE1 4.49Å; I185-F196 HydrophobicContact CG2-CD1 3.73Å; I185-F196 HydrophobicContact CG2-CE1 3.41Å; I185-F196 VanDerWaalsContact CG2-CE1 3.41Å; I185-F196 HydrophobicContact CG2-CZ 4.26Å
186D85.5Confident85.8Confident94 Ų9473.3 Ų73.350%0.50337%0.37SS..  trans-62.1145.6174.9-67.1-35.7000110.1E188 N189 R190D186-E188 PolarHBondContact O-N 3.32Å; D186-E188 VanDerWaalsContact O-N 3.16Å; D186-N189 PolarHBondContact O-N 3.22Å; D186-R190 PolarHBondContact O-N 3.18Å
187Q81.4Confident85.5Confident159 Ų15975.7 Ų75.774%0.74338%0.376SS*.G310 helixtrans-58.6-32.8-175.9-71-174.4-1.100112.6N189 R190Q187-N189 VanDerWaalsContact C-N 3.29Å; Q187-N189 PolarHBondContact O-N 3.05Å; Q187-R190 PolarHBondContact O-N 2.91Å
188E81.2Confident85.4Confident161 Ų16176.4 Ų76.475%0.75238%0.382SS*.G310 helixtrans-66.6-31.6179-60-176.4-18000112.5D186D186-E188 PolarHBondContact O-N 3.32Å; D186-E188 VanDerWaalsContact O-N 3.16Å
189N81Confident85.2Confident49 Ų4979.8 Ų79.826%0.26239%0.394SS..G310 helixtrans-92.66.8-176.9-66.2-23.3000113.1I185 D186 Q187 R191 F194I185-N189 HydrophobicContact CD1-CB 4.43Å; I185-N189 VanDerWaalsContact CD1-O 3.32Å; I185-N189 WeakPolarHBondContact CD1-O 3.41Å; I185-N189 HydrophobicContact CG1-CB 4.01Å; D186-N189 PolarHBondContact O-N 3.22Å; Q187-N189 VanDerWaalsContact C-N 3.29Å; Q187-N189 PolarHBondContact O-N 3.05Å; N189-R191 PolarHBondContact O-N 3.48Å; N189-F194 HydrophobicContact CB-CB 4.2Å; N189-F194 HydrophobicContact CB-CD1 3.88Å; N189-F194 HydrophobicContact CB-CE1 4.49Å; N189-F194 HydrophobicContact CB-CG 4.06Å; N189-F194 WeakPolarHBondContact O-CB 3.22Å; N189-F194 WeakPolarHBondContact OD1-CE1 3.39Å
190R79.6Confident85.1Confident124 Ų12482 Ų8247%0.46841%0.41SS..  trans-76.661.5175.9-68.4-177-175.5178.5-0.5111.9Y137 I185 D186 Q187Y137-R190 HydrophobicContact CE1-CB 4.42Å; Y137-R190 HydrophobicContact CE2-CB 4.11Å; Y137-R190 HydrophobicContact CE2-CG 4.19Å; I185-R190 HydrophobicContact CG1-CG 4.48Å; I185-R190 HydrophobicContact CG2-CG 3.82Å; D186-R190 PolarHBondContact O-N 3.18Å; Q187-R190 PolarHBondContact O-N 2.91Å
191R80.4Confident85.2Confident169 Ų16979.1 Ų79.164%0.63840%0.396SS*.SBendtrans-136.6150.3178-57.3-179.9-172.7176.93.1108.1N189 F194N189-R191 PolarHBondContact O-N 3.48Å; R191-F194 HydrophobicContact CB-CD2 3.96Å; R191-F194 HydrophobicContact CB-CE2 4.18Å; R191-F194 PolarHBondContact O-N 2.87Å
192S75.8Confident85.3Confident80 Ų8083.7 Ų83.756%0.55942%0.417SS*.THydrogen-bonded Turntrans-55.7140.7175-520000110.8
193G77.1Confident85.5Confident48 Ų4878 Ų7850%0.49540%0.396SS..THydrogen-bonded Turntrans91.3-6.7-174.800000115.7E136E136-G193 VanDerWaalsContact OE1-CA 3.28Å; E136-G193 WeakPolarHBondContact OE1-CA 3.23Å; E136-G193 PolarHBondContact OE1-N 3.03Å
194F85.9Confident85.7Confident91 Ų9176.9 Ų76.940%0.39939%0.388SS..PPolyproline II helixtrans-99.3142.1172.1-72.2-92.2000111Y137 N189 R191Y137-F194 WeakPolarHBondContact CB-O 3.46Å; Y137-F194 PolarHBondContact N-O 3.31Å; N189-F194 HydrophobicContact CB-CB 4.2Å; N189-F194 HydrophobicContact CB-CD1 3.88Å; N189-F194 HydrophobicContact CB-CE1 4.49Å; N189-F194 HydrophobicContact CB-CG 4.06Å; N189-F194 WeakPolarHBondContact O-CB 3.22Å; N189-F194 WeakPolarHBondContact OD1-CE1 3.39Å; R191-F194 HydrophobicContact CB-CD2 3.96Å; R191-F194 HydrophobicContact CB-CE2 4.18Å; R191-F194 PolarHBondContact O-N 2.87Å
195H86.1Confident86Confident89 Ų8975.1 Ų75.141%0.41237%0.372SS..EExtended strand (participates in β ladder)trans-92.1147.6178.4-59.5-85.4000111.6T135T135-H195 CarbonylContact O-C 3.59Å; T135-H195 VanDerWaalsContact O-CA 3.25Å; T135-H195 WeakPolarHBondContact O-CA 3.38Å
196F87.3Confident86.3Confident26 Ų2675 Ų7511%0.11437%0.371CS..EExtended strand (participates in β ladder)trans-68.8141.8165-71.2-92.4000110T135 Y137 M145 C183 I185 C198T135-F196 PolarHBondContact O-N 3.48Å; T135-F196 WeakPolarHBondContact OG1-CB 3.34Å; T135-F196 WeakPolarHBondContact OG1-CD2 3.47Å; Y137-F196 HydrophobicContact CD2-CE2 4.1Å; Y137-F196 AromaticContact CD2-CZ 3.72Å; Y137-F196 HydrophobicContact CD2-CZ 3.72Å; M145-F196 HydrophobicContact CB-CE1 4.03Å; M145-F196 HydrophobicContact CB-CE2 3.95Å; M145-F196 HydrophobicContact CB-CZ 3.56Å; M145-F196 HydrophobicContact CG-CE1 4.17Å; M145-F196 HydrophobicContact CG-CE2 4.49Å; M145-F196 HydrophobicContact CG-CZ 4.15Å; C183-F196 HydrophobicContact CB-CB 3.93Å; C183-F196 HydrophobicContact CB-CD1 4.37Å; C183-F196 HydrophobicContact CB-CG 4.45Å; I185-F196 HydrophobicContact CB-CD1 3.58Å; I185-F196 HydrophobicContact CB-CE1 3.83Å; I185-F196 HydrophobicContact CB-CG 4.34Å; I185-F196 HydrophobicContact CD1-CD1 4.41Å; I185-F196 HydrophobicContact CD1-CE1 4.49Å; I185-F196 HydrophobicContact CG2-CD1 3.73Å; I185-F196 HydrophobicContact CG2-CE1 3.41Å; I185-F196 VanDerWaalsContact CG2-CE1 3.41Å; I185-F196 HydrophobicContact CG2-CZ 4.26Å; F196-C198 PolarHBondContact O-N 3.02Å
197Q86.7Confident86.5Confident121 Ų12171.2 Ų71.257%0.56536%0.355SS*.EExtended strand (participates in β ladder)trans-87104.3169.8-67.6177.6-8.900108.4C183 S184C183-Q197 WeakPolarHBondContact CA-O 3.47Å; S184-Q197 PolarHBondContact N-O 3.34Å; S184-Q197 PolarHBondContact O-N 2.74Å
198C89.9Confident86.9Confident26 Ų2664.1 Ų64.118%0.17632%0.322CS..EExtended strand (participates in β ladder)trans-96.5142.3178.9-62.10000111.4L181 R182 C183 F196L181-C198 HydrophobicContact CD1-CB 4.2Å; R182-C198 WeakPolarHBondContact O-CA 3.27Å; C183-C198 HydrophobicContact CB-CB 4.04Å; C183-C198 WeakPolarHBondContact CB-SG 3.46Å; C183-C198 WeakPolarHBondContact SG-CB 3.49Å; C183-C198 CovalentContact SG-SG 2.03Å; C183-C198 PolarHBondContact SG-SG 3.46Å; F196-C198 PolarHBondContact O-N 3.02Å
199E88.9Confident87.4Confident108 Ų10856.6 Ų56.651%0.50529%0.288SS..PPolyproline II helixtrans-68.5140.9170.8-67.3-178.4170.100110.3R182R182-E199 HydrophobicContact CB-CB 4.39Å; R182-E199 HydrophobicContact CB-CG 4.29Å; R182-E199 WeakPolarHBondContact CD-OE2 3.48Å; R182-E199 IonicContact NH1-OE2 2.77Å; R182-E199 PolarHBondContact O-N 3.44Å
200P89.1Confident87.9Confident62 Ų6255.1 Ų55.140%0.40328%0.279SS..PPolyproline II helixtrans-62.313817624.5-32.6000111.3L132L132-P200 HydrophobicContact CD2-CB 3.73Å
201I91.1Very high88.5Confident12 Ų1250.7 Ų50.76%0.06226%0.263CS..EExtended strand (participates in β ladder)trans-100124.3179.6-62.9175.1000109.4L130 L131 I133 L151 R179 L181 L203L130-I201 CarbonylContact C-O 3.47Å; L130-I201 WeakPolarHBondContact CA-O 3.48Å; L131-I201 HydrophobicContact CB-CB 4.34Å; L131-I201 PolarHBondContact N-O 3.29Å; L131-I201 PolarHBondContact O-N 3.49Å; I133-I201 HydrophobicContact CD1-CD1 3.78Å; I133-I201 HydrophobicContact CG1-CD1 4.42Å; L151-I201 HydrophobicContact CD2-CD1 4.3Å; R179-I201 HydrophobicContact CB-CD1 4.22Å; R179-I201 HydrophobicContact CB-CG2 3.85Å; R179-I201 HydrophobicContact CG-CG2 3.51Å; L181-I201 HydrophobicContact CD1-CD1 4.17Å; I201-L203 PolarHBondContact O-N 3.46Å
202E91.1Very high89.2Confident97 Ų9743.3 Ų43.345%0.45324%0.237SC..EExtended strand (participates in β ladder)trans-64.9107.4169.6-67.7171.1-175.900110.1L130 R179L130-E202 HydrophobicContact CD2-CB 4.45Å; L130-E202 HydrophobicContact CD2-CG 3.87Å; R179-E202 PolarHBondContact NE-O 2.79Å; R179-E202 VanDerWaalsContact NE-O 3.09Å; R179-E202 PolarHBondContact NH2-O 3.36Å
203L93.3Very high90.1Very high1 Ų139.8 Ų39.81%0.00521%0.211CC..EExtended strand (participates in β ladder)trans-88.1-58.4-174.5-175.164.4000110.6G129 L131 L153 V155 I177 I201 L216 I218 I241 F385G129-L203 WeakPolarHBondContact O-CA 3.49Å; G129-L203 WeakPolarHBondContact O-CB 3.3Å; G129-L203 PolarHBondContact O-N 3Å; L131-L203 HydrophobicContact CB-CB 4.17Å; L131-L203 HydrophobicContact CB-CD2 4.38Å; L153-L203 HydrophobicContact CD1-CD1 4.33Å; V155-L203 HydrophobicContact CG1-CD1 4.24Å; I177-L203 HydrophobicContact CD1-CD1 3.54Å; I201-L203 PolarHBondContact O-N 3.46Å; L203-L216 HydrophobicContact CD2-CD2 3.62Å; L203-I218 HydrophobicContact CD2-CD1 3.87Å; L203-I241 HydrophobicContact CD2-CD1 4.12Å; L203-F385 HydrophobicContact CD1-CD1 4.19Å; L203-F385 HydrophobicContact CD1-CE1 4.32Å; L203-F385 HydrophobicContact CD2-CE1 4.45Å; L203-F385 HydrophobicContact CG-CD1 4.08Å; L203-F385 HydrophobicContact CG-CE1 3.97Å; L203-F385 WeakPolarHBondContact O-CA 3.46Å; L203-F385 WeakPolarHBondContact O-CD1 3.31Å
204F94.4Very high90.9Very high5 Ų537.6 Ų37.62%0.02219%0.188CC..EExtended strand (participates in β ladder)trans-147.2152.4179.669.1-96.6000112.7M109 L127 G129 M157 L206 L216 P384 F385M109-F204 HydrophobicContact CE-CE1 4.31Å; M109-F204 HydrophobicContact CE-CZ 4.11Å; M109-F204 HydrophobicContact SD-CZ 4.49Å; L127-F204 HydrophobicContact CB-CE2 4.44Å; L127-F204 HydrophobicContact CD2-CE2 3.87Å; L127-F204 HydrophobicContact CD2-CZ 4.18Å; L127-F204 HydrophobicContact CG-CE2 4.02Å; L127-F204 HydrophobicContact CG-CZ 4.49Å; G129-F204 PolarHBondContact N-O 3.38Å; G129-F204 PolarHBondContact O-N 3.41Å; M157-F204 HydrophobicContact CE-CD1 3.55Å; M157-F204 HydrophobicContact CE-CD2 3.82Å; M157-F204 HydrophobicContact CE-CE1 3.54Å; M157-F204 HydrophobicContact CE-CE2 3.83Å; M157-F204 HydrophobicContact CE-CG 3.69Å; M157-F204 HydrophobicContact CE-CZ 3.69Å; F204-L206 HydrophobicContact CD2-CG 4.05Å; F204-L206 HydrophobicContact CE2-CD1 4.42Å; F204-L206 HydrophobicContact CE2-CG 4.32Å; F204-L216 HydrophobicContact CD1-CD2 4.43Å; F204-L216 HydrophobicContact CE1-CD2 4.04Å; F204-P384 CarbonylContact C-O 3.51Å; F204-P384 WeakPolarHBondContact CA-O 3.31Å; F204-F385 HydrophobicContact CB-CD1 3.74Å; F204-F385 HydrophobicContact CB-CE1 3.76Å; F204-F385 HydrophobicContact CB-CG 4.19Å; F204-F385 HydrophobicContact CB-CZ 4.21Å; F204-F385 HydrophobicContact CD1-CE1 4.07Å; F204-F385 HydrophobicContact CG-CE1 4.3Å
205E93.7Very high91.4Very high36 Ų3633.2 Ų33.217%0.16817%0.169CC..EExtended strand (participates in β ladder)trans-132.4116.1169-172.3-176.7-147.600110L128 L317 H380 P384L128-E205 HydrophobicContact CD1-CB 3.99Å; L128-E205 HydrophobicContact CD1-CG 4.17Å; E205-L317 HydrophobicContact CG-CD2 4.37Å; E205-L317 WeakPolarHBondContact OE1-CD2 3.4Å; E205-H380 IonicContact OE2-CE1 2.61Å; E205-H380 PolarHBondContact OE2-CE1 2.96Å; E205-H380 IonicContact OE2-ND1 2.84Å; E205-H380 PolarHBondContact OE2-ND1 3.38Å; E205-P384 PolarHBondContact N-O 2.97Å; E205-P384 WeakPolarHBondContact O-CB 3.45Å
206L92.9Very high91.9Very high17 Ų1729 Ų299%0.08915%0.15CC..EExtended strand (participates in β ladder)trans-97.1121173.1-59.3177.8000109.5S126 L127 M157 L172 F204 S208 Y214 P384S126-L206 VanDerWaalsContact CA-O 3.24Å; S126-L206 WeakPolarHBondContact CA-O 3.49Å; S126-L206 WeakPolarHBondContact CB-O 3.5Å; L127-L206 HydrophobicContact CB-CB 4.1Å; L127-L206 HydrophobicContact CB-CD1 4.21Å; L127-L206 HydrophobicContact CB-CG 4.49Å; L127-L206 HydrophobicContact CD2-CD1 4.02Å; L127-L206 PolarHBondContact N-O 3.49Å; L127-L206 PolarHBondContact O-N 3.25Å; M157-L206 HydrophobicContact SD-CD1 4.08Å; M157-L206 HydrophobicContact SD-CD2 4.45Å; L172-L206 HydrophobicContact CD2-CD2 4.24Å; F204-L206 HydrophobicContact CD2-CG 4.05Å; F204-L206 HydrophobicContact CE2-CD1 4.42Å; F204-L206 HydrophobicContact CE2-CG 4.32Å; L206-S208 PolarHBondContact O-N 2.98Å; L206-Y214 HydrophobicContact CD1-CD1 4.49Å; L206-Y214 HydrophobicContact CD1-CE1 3.97Å; L206-P384 HydrophobicContact CD2-CB 3.61Å; L206-P384 HydrophobicContact CD2-CG 3.87Å
207G88.7Confident92.3Very high15 Ų1528 Ų2816%0.15515%0.145CC..SBendtrans-76.6-4.1175.700000115.2Q125Q125-G207 CarbonylContact O-C 3.59Å
208S90.7Very high92.7Very high10 Ų1022.2 Ų22.27%0.0712%0.118CC..  trans-143.3131.8172.757.20000110.9Q125 L206 D210Q125-S208 CarbonylContact O-C 3.53Å; Q125-S208 WeakPolarHBondContact O-CA 2.96Å; Q125-S208 PolarHBondContact O-N 3.31Å; L206-S208 PolarHBondContact O-N 2.98Å; S208-D210 WeakPolarHBondContact CB-OD2 3.16Å; S208-D210 PolarHBondContact O-N 3.47Å; S208-D210 PolarHBondContact OG-OD2 2.97Å
209C91.9Very high92.9Very high3 Ų321.9 Ų21.92%0.0211%0.113CC..  trans-95.483.1171-174.30000110.4R122 F124 Q125R122-C209 WeakPolarHBondContact CA-O 3.22Å; R122-C209 WeakPolarHBondContact CG-O 3.24Å; F124-C209 HydrophobicContact CB-CB 4.25Å; Q125-C209 PolarHBondContact O-N 3.03Å; Q125-C209 VanDerWaalsContact O-N 3.13Å
210D90.7Very high93Very high17 Ų1717.4 Ų17.49%0.0919%0.093CC..  trans-87-32.6-168.5-60.7-58.1000114.6R122 S208 Y214 R312R122-D210 PolarHBondContact NE-O 3.46Å; S208-D210 WeakPolarHBondContact CB-OD2 3.16Å; S208-D210 PolarHBondContact O-N 3.47Å; S208-D210 PolarHBondContact OG-OD2 2.97Å; D210-Y214 PolarHBondContact N-OH 3.5Å; D210-Y214 VanDerWaalsContact N-OH 3.15Å; D210-R312 WeakPolarHBondContact OD1-CA 3.38Å; D210-R312 WeakPolarHBondContact OD2-CD 3.39Å; D210-R312 WeakPolarHBondContact OD2-CG 3.22Å; D210-R312 IonicContact OD2-NE 2.69Å; D210-R312 PolarHBondContact OD2-NE 2.77Å
211Y93.5Very high93Very high32 Ų3214.5 Ų14.513%0.1257%0.074CC..  trans-110.1150.1-170.9-53-74.9000112.2Y159 N161 L172 Y214 R312Y159-Y211 HydrophobicContact CD1-CD2 4.21Å; Y159-Y211 HydrophobicContact CD1-CE1 4.42Å; Y159-Y211 AromaticContact CD1-CE2 3.9Å; Y159-Y211 HydrophobicContact CD1-CE2 3.9Å; Y159-Y211 AromaticContact CD1-CZ 3.99Å; Y159-Y211 AromaticContact CD2-CD1 3.24Å; Y159-Y211 HydrophobicContact CD2-CD1 3.24Å; Y159-Y211 HydrophobicContact CD2-CD2 4.01Å; Y159-Y211 AromaticContact CD2-CE1 3.31Å; Y159-Y211 HydrophobicContact CD2-CE1 3.31Å; Y159-Y211 HydrophobicContact CD2-CE2 4.08Å; Y159-Y211 AromaticContact CD2-CG 3.6Å; Y159-Y211 HydrophobicContact CD2-CG 3.6Å; Y159-Y211 AromaticContact CD2-CZ 3.74Å; Y159-Y211 HydrophobicContact CE1-CE1 4.36Å; Y159-Y211 HydrophobicContact CE1-CE2 4.23Å; Y159-Y211 AromaticContact CE1-CZ 3.91Å; Y159-Y211 AromaticContact CE2-CD1 3.69Å; Y159-Y211 HydrophobicContact CE2-CD1 3.69Å; Y159-Y211 AromaticContact CE2-CE1 3.26Å; Y159-Y211 HydrophobicContact CE2-CE1 3.26Å; Y159-Y211 HydrophobicContact CE2-CE2 4.43Å; Y159-Y211 HydrophobicContact CE2-CG 4.41Å; Y159-Y211 AromaticContact CE2-CZ 3.68Å; Y159-Y211 AromaticContact CG-CD1 3.84Å; Y159-Y211 HydrophobicContact CG-CD1 3.84Å; Y159-Y211 AromaticContact CG-CD2 3.7Å; Y159-Y211 HydrophobicContact CG-CD2 3.7Å; Y159-Y211 AromaticContact CG-CE1 3.93Å; Y159-Y211 HydrophobicContact CG-CE1 3.93Å; Y159-Y211 AromaticContact CG-CE2 3.8Å; Y159-Y211 HydrophobicContact CG-CE2 3.8Å; Y159-Y211 AromaticContact CG-CG 3.72Å; Y159-Y211 HydrophobicContact CG-CG 3.72Å; Y159-Y211 AromaticContact CG-CZ 3.9Å; Y159-Y211 AromaticContact CZ-CE1 3.81Å; Y159-Y211 AromaticContact CZ-CZ 3.75Å; N161-Y211 WeakPolarHBondContact OD1-CD1 3.34Å; L172-Y211 HydrophobicContact CD1-CE2 4.14Å; Y211-Y214 AromaticContact CD2-CE1 3.84Å; Y211-Y214 HydrophobicContact CD2-CE1 3.84Å; Y211-Y214 PolarHBondContact N-OH 2.92Å; Y211-Y214 VanDerWaalsContact N-OH 3.13Å; Y211-Y214 WeakPolarHBondContact O-CE2 3.29Å; Y211-R312 PolarHBondContact OH-NH1 2.88Å
212P93.6Very high92.6Very high13 Ų1314.3 Ų14.38%0.0848%0.075CC..SBendtrans-75.6-27.2-179.529.1-34.9000113.7E119 Y120 R160 R162E119-P212 HydrophobicContact CB-CB 4.05Å; Y120-P212 PolarHBondContact N-O 2.95Å; Y120-P212 WeakPolarHBondContact O-CA 3.47Å; R160-P212 WeakPolarHBondContact O-CD 3.38Å; R160-P212 WeakPolarHBondContact O-CG 3.25Å; R162-P212 HydrophobicContact CG-CB 4.46Å; R162-P212 HydrophobicContact CG-CG 4.03Å
213F94.8Very high91.7Very high6 Ų613.3 Ų13.33%0.0267%0.073CC..EExtended strand (participates in β ladder)trans-132.3137.8-177.3-51.4-73.2000110.6M109 Q117 L118 E119 Y159 R160 W169M109-F213 WeakPolarHBondContact O-CA 3.42Å; Q117-F213 HydrophobicContact CG-CE1 3.87Å; Q117-F213 HydrophobicContact CG-CZ 4.38Å; L118-F213 WeakPolarHBondContact O-CE1 3.09Å; E119-F213 HydrophobicContact CB-CE1 4.48Å; E119-F213 HydrophobicContact CB-CZ 4.49Å; E119-F213 HydrophobicContact CG-CE1 3.83Å; E119-F213 HydrophobicContact CG-CE2 4.49Å; E119-F213 HydrophobicContact CG-CZ 3.58Å; E119-F213 WeakPolarHBondContact OE1-CZ 3.31Å; Y159-F213 WeakPolarHBondContact CA-O 3.38Å; R160-F213 HydrophobicContact CB-CB 4.22Å; R160-F213 HydrophobicContact CB-CD2 4.5Å; R160-F213 PolarHBondContact N-O 3.23Å; R160-F213 VanDerWaalsContact N-O 3.12Å; W169-F213 HydrophobicContact CH2-CB 4.01Å; W169-F213 HydrophobicContact CZ3-CB 4.14Å
214Y95.5Very high90.2Very high2 Ų216.8 Ų16.81%0.0089%0.091CC..EExtended strand (participates in β ladder)trans-125.8146173.4-64.6-87.3000110M109 Y120 L127 M157 G158 L172 L206 D210 Y211M109-Y214 PolarHBondContact N-O 3.48Å; M109-Y214 PolarHBondContact O-N 3.02Å; M109-Y214 VanDerWaalsContact O-O 3.13Å; Y120-Y214 AromaticContact CD2-CD2 3.67Å; Y120-Y214 HydrophobicContact CD2-CD2 3.67Å; Y120-Y214 HydrophobicContact CD2-CE2 4.01Å; Y120-Y214 AromaticContact CE2-CD2 3.96Å; Y120-Y214 HydrophobicContact CE2-CD2 3.96Å; L127-Y214 HydrophobicContact CD2-CD2 4.14Å; L127-Y214 HydrophobicContact CD2-CE2 4.26Å; M157-Y214 HydrophobicContact SD-CD1 4.33Å; G158-Y214 WeakPolarHBondContact O-CA 3.43Å; L172-Y214 HydrophobicContact CD2-CE1 4.43Å; L206-Y214 HydrophobicContact CD1-CD1 4.49Å; L206-Y214 HydrophobicContact CD1-CE1 3.97Å; D210-Y214 PolarHBondContact N-OH 3.5Å; D210-Y214 VanDerWaalsContact N-OH 3.15Å; Y211-Y214 AromaticContact CD2-CE1 3.84Å; Y211-Y214 HydrophobicContact CD2-CE1 3.84Å; Y211-Y214 PolarHBondContact N-OH 2.92Å; Y211-Y214 VanDerWaalsContact N-OH 3.13Å; Y211-Y214 WeakPolarHBondContact O-CE2 3.29Å
215L95.4Very high88.4Confident0 Ų020.5 Ų20.50%013%0.132CC..EExtended strand (participates in β ladder)trans-125.8131.9175.3-179.568.6000108.3W69 F70 V106 Q108 M157 G158 W169W69-L215 HydrophobicContact CB-CD2 4.15Å; W69-L215 HydrophobicContact CD2-CD2 4.32Å; W69-L215 HydrophobicContact CE3-CD2 3.76Å; W69-L215 HydrophobicContact CE3-CG 4.46Å; F70-L215 WeakPolarHBondContact O-CD2 3.32Å; V106-L215 HydrophobicContact CG1-CD1 3.65Å; Q108-L215 HydrophobicContact CB-CD1 4.06Å; Q108-L215 HydrophobicContact CG-CD1 4.37Å; M157-L215 CarbonylContact C-O 3.58Å; M157-L215 WeakPolarHBondContact CA-O 3.46Å; G158-L215 PolarHBondContact N-O 3.43Å; G158-L215 PolarHBondContact O-N 3.18Å; W169-L215 HydrophobicContact CB-CD2 4.38Å; W169-L215 HydrophobicContact CD2-CB 3.81Å; W169-L215 HydrophobicContact CD2-CD2 3.6Å; W169-L215 HydrophobicContact CD2-CG 4.33Å; W169-L215 HydrophobicContact CE3-CB 3.44Å; W169-L215 VanDerWaalsContact CE3-CB 3.44Å; W169-L215 HydrophobicContact CE3-CD2 4.11Å; W169-L215 HydrophobicContact CE3-CG 4.43Å; W169-L215 HydrophobicContact CG-CD2 3.7Å; W169-L215 HydrophobicContact CH2-CB 3.77Å; W169-L215 HydrophobicContact CZ2-CB 4.12Å; W169-L215 HydrophobicContact CZ2-CD2 4.38Å; W169-L215 HydrophobicContact CZ3-CB 3.44Å; W169-L215 VanDerWaalsContact CZ3-CB 3.44Å
216L96.3Very high86.6Confident0 Ų025.8 Ų25.80%017%0.167CC..EExtended strand (participates in β ladder)trans-125.1116.4-179.9177.462.9000109.3V106 A107 M109 R156 M157 L203 F204 I218 I241 F385V106-L216 WeakPolarHBondContact CA-O 3.38Å; A107-L216 HydrophobicContact CB-CB 4.32Å; A107-L216 PolarHBondContact N-O 3.2Å; A107-L216 PolarHBondContact O-N 2.87Å; M109-L216 HydrophobicContact CE-CB 4.06Å; M109-L216 HydrophobicContact CE-CD2 4.43Å; R156-L216 WeakPolarHBondContact O-CA 3.4Å; M157-L216 HydrophobicContact CE-CD1 4.39Å; L203-L216 HydrophobicContact CD2-CD2 3.62Å; F204-L216 HydrophobicContact CD1-CD2 4.43Å; F204-L216 HydrophobicContact CE1-CD2 4.04Å; L216-I218 HydrophobicContact CD1-CG1 4.26Å; L216-I218 HydrophobicContact CD2-CD1 4.22Å; L216-I218 HydrophobicContact CG-CD1 4.27Å; L216-I218 HydrophobicContact CG-CG1 4.04Å; L216-I241 HydrophobicContact CD2-CD1 3.34Å; L216-I241 HydrophobicContact CG-CD1 4.4Å; L216-F385 HydrophobicContact CD1-CE1 4.09Å; L216-F385 HydrophobicContact CD1-CZ 3.91Å
217N95.7Very high85.2Confident4 Ų426.2 Ų26.22%0.02117%0.172CC..EExtended strand (participates in β ladder)trans-109.8122.3176.9-68.50.4000108.5F70 V104 F105 R156F70-N217 PolarHBondContact N-ND2 3.34Å; F70-N217 VanDerWaalsContact N-ND2 3.11Å; F70-N217 PolarHBondContact O-ND2 2.87Å; F70-N217 PolarHBondContact O-OD1 3.32Å; F70-N217 VanDerWaalsContact O-OD1 3.12Å; V104-N217 HydrophobicContact CG1-CB 3.93Å; F105-N217 CarbonylContact O-C 3.59Å; F105-N217 WeakPolarHBondContact O-CA 3.22Å; R156-N217 HydrophobicContact CB-CB 4.38Å; R156-N217 PolarHBondContact N-O 3.3Å; R156-N217 PolarHBondContact O-N 3.06Å
218I95.5Very high84.5Confident0 Ų029.9 Ų29.90%019%0.188CC..EExtended strand (participates in β ladder)trans-118.3127.8179.6-54.7-175.5000108.4M55 F105 L131 L153 E154 V155 L203 L216 I241M55-I218 HydrophobicContact CE-CB 4.12Å; M55-I218 HydrophobicContact CE-CD1 3.64Å; M55-I218 HydrophobicContact CE-CG1 3.73Å; M55-I218 HydrophobicContact SD-CD1 3.92Å; F105-I218 HydrophobicContact CB-CB 4.34Å; F105-I218 PolarHBondContact N-O 3.4Å; F105-I218 PolarHBondContact O-N 3.21Å; L131-I218 HydrophobicContact CD1-CD1 4.33Å; L153-I218 HydrophobicContact CB-CG2 4.21Å; L153-I218 HydrophobicContact CD2-CG2 3.96Å; L153-I218 HydrophobicContact CG-CG2 4.48Å; E154-I218 CarbonylContact O-C 3.55Å; E154-I218 WeakPolarHBondContact O-CA 3.26Å; V155-I218 HydrophobicContact CG1-CD1 4.48Å; V155-I218 HydrophobicContact CG1-CG1 4.11Å; V155-I218 HydrophobicContact CG1-CG2 4.27Å; L203-I218 HydrophobicContact CD2-CD1 3.87Å; L216-I218 HydrophobicContact CD1-CG1 4.26Å; L216-I218 HydrophobicContact CD2-CD1 4.22Å; L216-I218 HydrophobicContact CG-CD1 4.27Å; L216-I218 HydrophobicContact CG-CG1 4.04Å; I218-I241 HydrophobicContact CD1-CD1 4.18Å
219R93.8Very high84.1Confident19 Ų1932.7 Ų32.77%0.07220%0.199CC..EExtended strand (participates in β ladder)trans-112.6144.9167.2-61.8-174.4178.6104.9-3.2109.8D60 V104 E154 P221D60-R219 IonicContact OD2-CZ 3.34Å; D60-R219 IonicContact OD2-NE 3.73Å; D60-R219 IonicContact OD2-NH2 3.07Å; D60-R219 PolarHBondContact OD2-NH2 2.95Å; V104-R219 HydrophobicContact CG1-CG 4.39Å; V104-R219 HydrophobicContact CG2-CG 4.02Å; E154-R219 HydrophobicContact CB-CB 4.21Å; E154-R219 PolarHBondContact N-O 3.2Å; E154-R219 PolarHBondContact O-N 3.47Å; R219-P221 WeakPolarHBondContact O-CD 2.99Å
220I91.9Very high83.9Confident14 Ų1433.6 Ų33.67%0.07220%0.204CC..  trans-111.895.7177.3-56.3-175.9000107.3F105 L151 L153 G222 N230 I233 L236 L239F105-I220 HydrophobicContact CD2-CD1 4.45Å; F105-I220 HydrophobicContact CD2-CG1 4.5Å; F105-I220 HydrophobicContact CE2-CD1 3.98Å; F105-I220 HydrophobicContact CE2-CG1 4.26Å; L151-I220 HydrophobicContact CD1-CG2 4.25Å; L153-I220 HydrophobicContact CD2-CD1 4.13Å; L153-I220 HydrophobicContact CD2-CG1 3.71Å; I220-G222 PolarHBondContact O-N 3.08Å; I220-N230 HydrophobicContact CG2-CB 4.27Å; I220-N230 VanDerWaalsContact CG2-ND2 3.27Å; I220-N230 WeakPolarHBondContact CG2-ND2 3.21Å; I220-I233 HydrophobicContact CG2-CD1 4.41Å; I220-L236 HydrophobicContact CD1-CD2 3.61Å; I220-L239 HydrophobicContact CD1-CD1 4.08Å
221P89.3Confident83.5Confident1 Ų139 Ų391%0.00622%0.223CC..  trans-64.6133.9-176.625.9-35.9000111.7R101 R152 E154 R219 N230R101-P221 HydrophobicContact CG-CB 4.1Å; R152-P221 HydrophobicContact CG-CG 4.33Å; R152-P221 WeakPolarHBondContact O-CD 3.4Å; E154-P221 HydrophobicContact CG-CG 4.08Å; R219-P221 WeakPolarHBondContact O-CD 2.99Å; P221-N230 PolarHBondContact O-ND2 3.45Å
222G82Confident83.1Confident9 Ų943 Ų439%0.09324%0.243CC..  trans-83.8-167.5176.500000114.1I220 N224I220-G222 PolarHBondContact O-N 3.08Å; G222-N224 PolarHBondContact O-N 3.37Å
223N71.7Confident82.8Confident76 Ų7643.5 Ų43.541%0.40625%0.245SC..  trans-78.1106.4172.3177.920.9000110.7A227 N228 R231N223-A227 PolarHBondContact OD1-O 3.21Å; N223-A227 VanDerWaalsContact OD1-O 3.13Å; N223-N228 PolarHBondContact ND2-OD1 2.91Å; N223-N228 PolarHBondContact OD1-OD1 2.64Å; N223-R231 PolarHBondContact ND2-NH2 2.82Å
224N62.8Low82.4Confident73 Ų7343.4 Ų43.439%0.3925%0.245SC..BIsolated β-bridgetrans-105.9104.2171.2-83.8-13.3000109.2D99 G222 T226 A227D99-N224 PolarHBondContact OD2-ND2 2.91Å; D99-N224 PolarHBondContact OD2-OD1 3.4Å; G222-N224 PolarHBondContact O-N 3.37Å; N224-T226 PolarHBondContact O-N 2.9Å; N224-A227 PolarHBondContact N-O 2.88Å; N224-A227 PolarHBondContact O-N 3.28Å
225G55.9Low82Confident84 Ų8443.8 Ų43.887%0.86625%0.247SC*.THydrogen-bonded Turntrans35.9-52.6165.100000120.3
226T56.7Low81.7Confident147 Ų14745 Ų4590%0.90225%0.253SS*.THydrogen-bonded Turntrans-99.2-18.6177.652.80000113.9N224N224-T226 PolarHBondContact O-N 2.9Å
227A63.1Low81.3Confident25 Ų2546.2 Ų46.221%0.20726%0.26CS..BIsolated β-bridgetrans-136.6117.3-172.600000112.5N223 N224 F229N223-A227 PolarHBondContact OD1-O 3.21Å; N223-A227 VanDerWaalsContact OD1-O 3.13Å; N224-A227 PolarHBondContact N-O 2.88Å; N224-A227 PolarHBondContact O-N 3.28Å; A227-F229 HydrophobicContact CB-CD2 4Å; A227-F229 HydrophobicContact CB-CE1 4.38Å; A227-F229 HydrophobicContact CB-CE2 3.34Å; A227-F229 HydrophobicContact CB-CZ 3.55Å; A227-F229 PolarHBondContact O-N 3.24Å
228N73.1Confident81Confident92 Ų9249.9 Ų49.949%0.49228%0.277SS..  trans-92.582.4-178.5-65.7-25.8000110N223 R231N223-N228 PolarHBondContact ND2-OD1 2.91Å; N223-N228 PolarHBondContact OD1-OD1 2.64Å; N228-R231 PolarHBondContact ND2-NH1 3.47Å; N228-R231 PolarHBondContact ND2-NH2 3.25Å; N228-R231 PolarHBondContact OD1-NH2 3.45Å
229F83.3Confident80.9Confident69 Ų6950 Ų5030%0.30328%0.278SS..  trans-94.7158.7173.4-55.9-54.8000111.9A227 R231A227-F229 HydrophobicContact CB-CD2 4Å; A227-F229 HydrophobicContact CB-CE1 4.38Å; A227-F229 HydrophobicContact CB-CE2 3.34Å; A227-F229 HydrophobicContact CB-CZ 3.55Å; A227-F229 PolarHBondContact O-N 3.24Å; F229-R231 VanDerWaalsContact C-N 3.29Å; F229-R231 PolarHBondContact O-N 2.71Å
230N86.6Confident80.9Confident22 Ų2249.7 Ų49.712%0.11828%0.277CS..SBendtrans5340.3169.1-66.3-32.4000114.8L151 R152 I220 P221 I233L151-N230 WeakPolarHBondContact CA-OD1 3.44Å; R152-N230 PolarHBondContact N-OD1 3.48Å; R152-N230 PolarHBondContact O-ND2 3.08Å; R152-N230 PolarHBondContact O-OD1 3.05Å; I220-N230 HydrophobicContact CG2-CB 4.27Å; I220-N230 VanDerWaalsContact CG2-ND2 3.27Å; I220-N230 WeakPolarHBondContact CG2-ND2 3.21Å; P221-N230 PolarHBondContact O-ND2 3.45Å; N230-I233 HydrophobicContact CB-CD1 4.21Å
231R83.3Confident81Confident132 Ų13249 Ų4950%0.49827%0.274SS..THydrogen-bonded Turntrans-84.2148.6173-68-172.6171.4-172.5-3.7110.3N223 N228 F229 I233N223-R231 PolarHBondContact ND2-NH2 2.82Å; N228-R231 PolarHBondContact ND2-NH1 3.47Å; N228-R231 PolarHBondContact ND2-NH2 3.25Å; N228-R231 PolarHBondContact OD1-NH2 3.45Å; F229-R231 VanDerWaalsContact C-N 3.29Å; F229-R231 PolarHBondContact O-N 2.71Å; R231-I233 PolarHBondContact O-N 3.42Å
232E84.8Confident81.2Confident115 Ų11550.9 Ų50.954%0.53728%0.284SS..THydrogen-bonded Turntrans59.727.9174.6-47.3-177.1174.700114.3K144 M145 G146 P149 G234K144-E232 CarbonylContact O-C 3.13Å; K144-E232 WeakPolarHBondContact O-CA 3.41Å; K144-E232 WeakPolarHBondContact O-CB 3.4Å; M145-E232 CarbonylContact C-O 3.3Å; M145-E232 WeakPolarHBondContact CA-O 3.13Å; G146-E232 WeakPolarHBondContact CA-OE2 3.33Å; G146-E232 PolarHBondContact N-O 3.19Å; P149-E232 WeakPolarHBondContact CG-O 3.34Å; E232-G234 PolarHBondContact O-N 3.47Å
233I87.7Confident81.7Confident24 Ų2450.4 Ų50.412%0.12328%0.279CS..BIsolated β-bridgetrans-82.98.1178.361.7167.6000113.6T135 P149 L151 L181 I220 N230 R231T135-I233 WeakPolarHBondContact CG2-O 3.49Å; P149-I233 HydrophobicContact CB-CG2 4.12Å; P149-I233 HydrophobicContact CG-CG2 4.24Å; L151-I233 HydrophobicContact CD1-CD1 4.07Å; L151-I233 HydrophobicContact CD1-CG2 4.23Å; L181-I233 HydrophobicContact CD2-CB 4.32Å; I220-I233 HydrophobicContact CG2-CD1 4.41Å; N230-I233 HydrophobicContact CB-CD1 4.21Å; R231-I233 PolarHBondContact O-N 3.42Å
234G85.8Confident82.6Confident3 Ų349.1 Ų49.13%0.03127%0.271CS..  trans78.2-176.6-172.900000113W143 E232 L236W143-G234 WeakPolarHBondContact O-CA 3.26Å; E232-G234 PolarHBondContact O-N 3.47Å; G234-L236 PolarHBondContact O-N 2.96Å
235R87.3Confident83.9Confident11 Ų1146.3 Ų46.34%0.04226%0.256CS..EExtended strand (participates in β ladder)trans-84.4105.3169.7176.9-174171.683.98.2108.2G87 R88 P89 T135 E136 W143 T237G87-R235 PolarHBondContact O-NH2 3.33Å; R88-R235 PolarHBondContact O-NH2 3.19Å; R88-R235 VanDerWaalsContact O-NH2 3.16Å; P89-R235 VanDerWaalsContact CA-NH1 3.28Å; T135-R235 CarbonylContact C-O 3.53Å; T135-R235 WeakPolarHBondContact CA-O 3.4Å; E136-R235 PolarHBondContact N-O 3.36Å; E136-R235 WeakPolarHBondContact OE2-CD 3.49Å; E136-R235 IonicContact OE2-NE 3.91Å; E136-R235 PolarHBondContact OE2-NE 2.91Å; E136-R235 VanDerWaalsContact OE2-NE 3.07Å; W143-R235 HydrophobicContact CB-CB 4.05Å; W143-R235 HydrophobicContact CD2-CB 4.23Å; W143-R235 HydrophobicContact CE3-CB 4.29Å; W143-R235 HydrophobicContact CG-CB 4.13Å; R235-T237 PolarHBondContact O-N 2.98Å
236L89.1Confident85.5Confident26 Ų2644.3 Ų44.314%0.13622%0.224CC..EExtended strand (participates in β ladder)trans-64.6129.5173.3-176.267.6000109.7L86 F105 I133 T135 I220 G234 L239L86-L236 HydrophobicContact CD1-CB 4.36Å; L86-L236 HydrophobicContact CD1-CD2 4.31Å; L86-L236 HydrophobicContact CD1-CG 4.16Å; L86-L236 VanDerWaalsContact CD1-O 3.31Å; L86-L236 WeakPolarHBondContact CD1-O 3.46Å; F105-L236 HydrophobicContact CE1-CD2 4.32Å; F105-L236 HydrophobicContact CE2-CD2 4.14Å; F105-L236 HydrophobicContact CZ-CD2 3.59Å; I133-L236 HydrophobicContact CG2-CD1 3.49Å; I133-L236 VanDerWaalsContact CG2-CD1 3.49Å; T135-L236 HydrophobicContact CG2-CD1 4.48Å; I220-L236 HydrophobicContact CD1-CD2 3.61Å; G234-L236 PolarHBondContact O-N 2.96Å; L236-L239 HydrophobicContact CD1-CD2 3.69Å; L236-L239 HydrophobicContact CD1-CG 4.28Å; L236-L239 HydrophobicContact CD2-CD2 4.46Å; L236-L239 HydrophobicContact CD2-CG 4.42Å
237T87.8Confident87.2Confident24 Ų2439.1 Ų39.115%0.14719%0.191CC..EExtended strand (participates in β ladder)trans-105.1-55.7172.450.30000110.3E134 E136 R235E134-T237 PolarHBondContact O-N 2.93Å; E134-T237 PolarHBondContact O-OG1 3.48Å; E134-T237 VanDerWaalsContact O-OG1 3.09Å; E136-T237 HydrophobicContact CB-CG2 3.69Å; R235-T237 PolarHBondContact O-N 2.98Å
238E90.7Very high88.5Confident82 Ų8238.4 Ų38.438%0.38319%0.186SC..EExtended strand (participates in β ladder)trans-143.6155.2-172.6-63.4-177.8-16600111.2L54 E134L54-E238 HydrophobicContact CD1-CB 4.15Å; L54-E238 HydrophobicContact CD1-CG 4.39Å; L54-E238 VanDerWaalsContact CD1-OE2 3.32Å; L54-E238 WeakPolarHBondContact CD1-OE2 3.45Å; E134-E238 HydrophobicContact CB-CB 4.39Å; E134-E238 PolarHBondContact N-O 2.94Å
239L93.3Very high89.4Confident1 Ų135.5 Ų35.51%0.00518%0.178CC..EExtended strand (participates in β ladder)trans-119.4127.5169.1-65.6-178.5000108.8M55 F105 L131 I133 I220 L236M55-L239 HydrophobicContact CB-CB 4.12Å; M55-L239 VanDerWaalsContact CB-O 3.29Å; M55-L239 WeakPolarHBondContact CB-O 3.46Å; M55-L239 HydrophobicContact CG-CB 3.98Å; M55-L239 VanDerWaalsContact CG-O 3.28Å; M55-L239 WeakPolarHBondContact CG-O 3.4Å; M55-L239 PolarHBondContact N-O 3.48Å; M55-L239 HydrophobicContact SD-CB 3.59Å; M55-L239 VanDerWaalsContact SD-CB 3.59Å; M55-L239 HydrophobicContact SD-CD1 4.02Å; M55-L239 HydrophobicContact SD-CG 4.48Å; F105-L239 HydrophobicContact CB-CD1 3.89Å; F105-L239 HydrophobicContact CD1-CB 4.17Å; F105-L239 HydrophobicContact CD1-CD1 3.59Å; F105-L239 HydrophobicContact CD1-CG 3.93Å; F105-L239 HydrophobicContact CD2-CD1 3.66Å; F105-L239 HydrophobicContact CE1-CD1 3.98Å; F105-L239 HydrophobicContact CE1-CG 4.05Å; F105-L239 HydrophobicContact CE2-CD1 4.05Å; F105-L239 HydrophobicContact CG-CD1 3.43Å; F105-L239 VanDerWaalsContact CG-CD1 3.43Å; F105-L239 HydrophobicContact CG-CG 4.29Å; F105-L239 HydrophobicContact CZ-CD1 4.2Å; L131-L239 HydrophobicContact CD1-CB 4.36Å; L131-L239 HydrophobicContact CD1-CD2 4.41Å; I133-L239 HydrophobicContact CB-CD2 4.14Å; I133-L239 HydrophobicContact CD1-CD2 4.28Å; I133-L239 HydrophobicContact CG1-CD2 3.77Å; I133-L239 HydrophobicContact CG2-CD2 3.87Å; I220-L239 HydrophobicContact CD1-CD1 4.08Å; L236-L239 HydrophobicContact CD1-CD2 3.69Å; L236-L239 HydrophobicContact CD1-CG 4.28Å; L236-L239 HydrophobicContact CD2-CD2 4.46Å; L236-L239 HydrophobicContact CD2-CG 4.42Å
240N93.6Very high89.9Confident13 Ų1332.7 Ų32.77%0.0717%0.165CC..EExtended strand (participates in β ladder)trans-116.9140.6178.2-77.9-42.9000109.1F53 L54 L132 E134F53-N240 CarbonylContact O-C 3.57Å; F53-N240 WeakPolarHBondContact O-CA 3.43Å; L54-N240 VanDerWaalsContact CA-OD1 3.26Å; L54-N240 WeakPolarHBondContact CA-OD1 3.42Å; L54-N240 WeakPolarHBondContact CD1-OD1 3.28Å; L132-N240 HydrophobicContact CB-CB 3.91Å; L132-N240 HydrophobicContact CD1-CB 4.48Å; L132-N240 PolarHBondContact N-O 3.07Å; L132-N240 PolarHBondContact O-N 2.9Å; E134-N240 PolarHBondContact OE1-ND2 3.01Å
241I94.1Very high90.2Very high0 Ų031.6 Ų31.60%016%0.16CC..EExtended strand (participates in β ladder)trans-120.5122175.2-65.5-179.9000109N52 F53 M55 A107 L130 L131 L203 L216 I218N52-I241 CarbonylContact C-O 3.51Å; N52-I241 WeakPolarHBondContact CA-O 3.42Å; N52-I241 PolarHBondContact OD1-O 3.47Å; F53-I241 HydrophobicContact CB-CB 4.33Å; F53-I241 PolarHBondContact N-O 2.76Å; F53-I241 PolarHBondContact O-N 3.16Å; M55-I241 HydrophobicContact CE-CD1 3.82Å; M55-I241 HydrophobicContact CG-CD1 4.04Å; M55-I241 HydrophobicContact CG-CG1 4.07Å; M55-I241 HydrophobicContact SD-CD1 3.57Å; M55-I241 VanDerWaalsContact SD-CD1 3.57Å; M55-I241 HydrophobicContact SD-CG1 3.9Å; A107-I241 HydrophobicContact CB-CD1 4.02Å; L130-I241 CarbonylContact O-C 3.5Å; L130-I241 VanDerWaalsContact O-CA 3.32Å; L130-I241 WeakPolarHBondContact O-CA 3.48Å; L131-I241 HydrophobicContact CD1-CD1 4.27Å; L131-I241 HydrophobicContact CD1-CG1 3.74Å; L203-I241 HydrophobicContact CD2-CD1 4.12Å; L216-I241 HydrophobicContact CD2-CD1 3.34Å; L216-I241 HydrophobicContact CG-CD1 4.4Å; I218-I241 HydrophobicContact CD1-CD1 4.18Å
242I92.1Very high90.7Very high40 Ų4031.3 Ų31.321%0.20516%0.162CC..EExtended strand (participates in β ladder)trans-95113.1168.5-60.2179.2000107.6W50 L130 L132 I244W50-I242 HydrophobicContact CB-CG2 4.34Å; W50-I242 HydrophobicContact CE3-CG2 4.17Å; L130-I242 HydrophobicContact CB-CB 4.37Å; L130-I242 PolarHBondContact N-O 3.4Å; L130-I242 PolarHBondContact O-N 3.4Å; L132-I242 HydrophobicContact CD1-CD1 3.44Å; L132-I242 VanDerWaalsContact CD1-CD1 3.44Å; L132-I242 HydrophobicContact CD1-CG1 3.83Å; L132-I242 HydrophobicContact CG-CD1 4.29Å; I242-I244 HydrophobicContact CG2-CD1 4.5Å; I242-I244 HydrophobicContact CG2-CG1 4.05Å
243E92.4Very high91.2Very high0 Ų027 Ų270%014%0.144CC..EExtended strand (participates in β ladder)trans-93132.9172-179.4-88.4113.400109.1W50 M51 F53 M109 Y120 L127 L128 H245W50-E243 CarbonylContact C-O 3.42Å; W50-E243 WeakPolarHBondContact CA-O 3.46Å; W50-E243 VanDerWaalsContact CB-O 3.25Å; W50-E243 WeakPolarHBondContact CB-O 3.33Å; M51-E243 PolarHBondContact N-O 3.26Å; M51-E243 PolarHBondContact O-N 3.31Å; F53-E243 HydrophobicContact CD2-CB 4.07Å; F53-E243 HydrophobicContact CE2-CB 3.65Å; F53-E243 HydrophobicContact CE2-CG 4.39Å; M109-E243 HydrophobicContact SD-CB 4.32Å; M109-E243 HydrophobicContact SD-CG 4.25Å; Y120-E243 WeakPolarHBondContact CE1-OE2 3.46Å; Y120-E243 VanDerWaalsContact OH-CD 3.27Å; Y120-E243 PolarHBondContact OH-OE2 2.95Å; L127-E243 HydrophobicContact CD1-CG 3.51Å; L127-E243 WeakPolarHBondContact CD1-OE1 3.24Å; L127-E243 HydrophobicContact CD2-CG 4.49Å; L127-E243 HydrophobicContact CG-CG 3.97Å; L128-E243 CarbonylContact O-C 3.55Å; L128-E243 VanDerWaalsContact O-CA 3.32Å; L128-E243 WeakPolarHBondContact O-CA 3.46Å; E243-H245 VanDerWaalsContact CD-ND1 3.32Å; E243-H245 VanDerWaalsContact OE1-CB 3.27Å; E243-H245 WeakPolarHBondContact OE1-CB 3.49Å; E243-H245 IonicContact OE1-CE1 3.52Å; E243-H245 IonicContact OE1-CG 3.58Å; E243-H245 PolarHBondContact OE1-N 3.25Å; E243-H245 VanDerWaalsContact OE1-N 3.14Å; E243-H245 IonicContact OE1-ND1 2.8Å; E243-H245 PolarHBondContact OE1-ND1 3.37Å; E243-H245 IonicContact OE2-CE1 3.55Å; E243-H245 IonicContact OE2-ND1 3.95Å; E243-H245 PolarHBondContact OE2-ND1 3.44Å; E243-H245 VanDerWaalsContact OE2-ND1 3.17Å
244I90.7Very high91.5Very high48 Ų4827.7 Ų27.725%0.24615%0.145CC..EExtended strand (participates in β ladder)trans-123.7126178.3-54176.4000108.4A49 W50 L128 L130 I242A49-I244 WeakPolarHBondContact O-CA 3.36Å; W50-I244 HydrophobicContact CB-CG1 3.99Å; L128-I244 HydrophobicContact CB-CB 4.3Å; L128-I244 HydrophobicContact CD2-CD1 4.26Å; L128-I244 PolarHBondContact N-O 2.93Å; L128-I244 PolarHBondContact O-N 3.42Å; L130-I244 HydrophobicContact CD1-CD1 3.92Å; I242-I244 HydrophobicContact CG2-CD1 4.5Å; I242-I244 HydrophobicContact CG2-CG1 4.05Å
245H91.5Very high91.9Very high15 Ų1527.6 Ų27.67%0.06914%0.143CC..EExtended strand (participates in β ladder)trans-129.1158.2177.454.7-89.8000111.6S48 A49 F124 L127 E243S48-H245 VanDerWaalsContact CA-O 3.31Å; S48-H245 WeakPolarHBondContact CA-O 3.48Å; A49-H245 PolarHBondContact N-O 3.38Å; A49-H245 PolarHBondContact O-N 2.96Å; F124-H245 HydrophobicContact CB-CB 4.16Å; F124-H245 AromaticContact CD1-CD2 3.83Å; F124-H245 AromaticContact CE1-CD2 3.98Å; F124-H245 HydrophobicContact CG-CB 4.43Å; F124-H245 AromaticContact CG-CD2 3.85Å; L127-H245 HydrophobicContact CD1-CB 4.05Å; E243-H245 VanDerWaalsContact CD-ND1 3.32Å; E243-H245 VanDerWaalsContact OE1-CB 3.27Å; E243-H245 WeakPolarHBondContact OE1-CB 3.49Å; E243-H245 IonicContact OE1-CE1 3.52Å; E243-H245 IonicContact OE1-CG 3.58Å; E243-H245 PolarHBondContact OE1-N 3.25Å; E243-H245 VanDerWaalsContact OE1-N 3.14Å; E243-H245 IonicContact OE1-ND1 2.8Å; E243-H245 PolarHBondContact OE1-ND1 3.37Å; E243-H245 IonicContact OE2-CE1 3.55Å; E243-H245 IonicContact OE2-ND1 3.95Å; E243-H245 PolarHBondContact OE2-ND1 3.44Å; E243-H245 VanDerWaalsContact OE2-ND1 3.17Å
246Q89.6Confident92.3Very high42 Ų4229.5 Ų29.520%0.19616%0.158CC..EExtended strand (participates in β ladder)trans-71.2136.1170.5-158.3177.3-53.500109.3P47 F124 G248 F250 T251P47-Q246 WeakPolarHBondContact O-CA 3.36Å; P47-Q246 VanDerWaalsContact O-CG 3.28Å; P47-Q246 WeakPolarHBondContact O-CG 3.37Å; F124-Q246 VanDerWaalsContact CA-O 3.26Å; F124-Q246 WeakPolarHBondContact CA-O 3.46Å; F124-Q246 WeakPolarHBondContact CD1-O 3.29Å; F124-Q246 WeakPolarHBondContact O-CB 3.38Å; F124-Q246 PolarHBondContact O-N 3.43Å; Q246-G248 PolarHBondContact O-N 2.93Å; Q246-F250 HydrophobicContact CG-CD1 4.25Å; Q246-T251 PolarHBondContact NE2-OG1 3.27Å
247N91.1Very high92.6Very high37 Ų3728.7 Ų28.720%0.19815%0.154CC..  trans-70.5125.9179.9-167.4-38000110.4P45 S46 P47 G249 F250 T251P45-N247 WeakPolarHBondContact CB-ND2 3.27Å; P45-N247 HydrophobicContact CG-CB 4.32Å; P45-N247 WeakPolarHBondContact CG-OD1 3.29Å; S46-N247 WeakPolarHBondContact O-CB 3.43Å; P47-N247 PolarHBondContact O-N 3.2Å; N247-G249 PolarHBondContact O-N 2.84Å; N247-G249 PolarHBondContact OD1-N 3.36Å; N247-G249 VanDerWaalsContact OD1-N 3.09Å; N247-F250 HydrophobicContact CB-CB 4.12Å; N247-F250 WeakPolarHBondContact O-CA 3.3Å; N247-F250 WeakPolarHBondContact O-CB 3.13Å; N247-F250 PolarHBondContact O-N 3Å; N247-T251 PolarHBondContact O-N 3.01Å; N247-T251 PolarHBondContact O-OG1 3.47Å
248G91.8Very high92.9Very high11 Ų1127.8 Ų27.811%0.11315%0.148CC..Hα-helixtrans-60.3-31.2-177.300000113.7Q246 K252Q246-G248 PolarHBondContact O-N 2.93Å; G248-K252 PolarHBondContact O-N 3.46Å
249G92.1Very high93.2Very high30 Ų3026.9 Ų26.931%0.30915%0.148SC..Hα-helixtrans-69.6-36.5173.700000112.6P45 N247 K252 V253P45-G249 VanDerWaalsContact CG-C 3.46Å; N247-G249 PolarHBondContact O-N 2.84Å; N247-G249 PolarHBondContact OD1-N 3.36Å; N247-G249 VanDerWaalsContact OD1-N 3.09Å; G249-K252 PolarHBondContact O-N 2.76Å; G249-V253 PolarHBondContact O-N 2.96Å
250F92.1Very high93.3Very high10 Ų1032 Ų324%0.04418%0.175CC..Hα-helixtrans-66.5-46.7175.6175.5-96.1000109.5A44 P45 P47 Q246 N247 K252 V253 W254 L498A44-F250 HydrophobicContact CB-CD2 3.95Å; P45-F250 VanDerWaalsContact CD-N 3.35Å; P45-F250 HydrophobicContact CG-CB 4.21Å; P47-F250 HydrophobicContact CB-CD1 4.2Å; P47-F250 HydrophobicContact CB-CD2 4.23Å; P47-F250 HydrophobicContact CB-CE1 4.14Å; P47-F250 HydrophobicContact CB-CE2 4.17Å; P47-F250 HydrophobicContact CB-CG 4.26Å; P47-F250 HydrophobicContact CB-CZ 4.13Å; P47-F250 HydrophobicContact CG-CD2 4.15Å; P47-F250 HydrophobicContact CG-CE2 3.97Å; P47-F250 HydrophobicContact CG-CZ 4.3Å; Q246-F250 HydrophobicContact CG-CD1 4.25Å; N247-F250 HydrophobicContact CB-CB 4.12Å; N247-F250 WeakPolarHBondContact O-CA 3.3Å; N247-F250 WeakPolarHBondContact O-CB 3.13Å; N247-F250 PolarHBondContact O-N 3Å; F250-K252 PolarHBondContact O-N 3.41Å; F250-V253 PolarHBondContact O-N 3.47Å; F250-V253 VanDerWaalsContact O-N 3.11Å; F250-W254 HydrophobicContact CE1-CB 4.27Å; F250-W254 HydrophobicContact CE1-CD2 4.41Å; F250-W254 HydrophobicContact CE1-CE3 4.44Å; F250-W254 HydrophobicContact CE1-CG 4.36Å; F250-W254 HydrophobicContact CZ-CD2 4.37Å; F250-W254 AromaticContact CZ-CE3 3.95Å; F250-W254 HydrophobicContact CZ-CE3 3.95Å; F250-W254 HydrophobicContact CZ-CZ3 4.49Å; F250-W254 VanDerWaalsContact O-CB 3.31Å; F250-W254 WeakPolarHBondContact O-CB 3.39Å; F250-W254 PolarHBondContact O-N 3.2Å; F250-L498 HydrophobicContact CE2-CB 4.5Å; F250-L498 HydrophobicContact CE2-CD1 4.28Å; F250-L498 HydrophobicContact CZ-CB 4.24Å; F250-L498 HydrophobicContact CZ-CD1 3.8Å
251T93.7Very high93.4Very high0 Ų031.8 Ų31.80%017%0.173CC..Hα-helixtrans-52.9-42.8174.7-55.90000112.1W123 Q125 Q246 N247 W254 L255W123-T251 HydrophobicContact CE3-CG2 3.99Å; W123-T251 WeakPolarHBondContact O-CB 3.2Å; W123-T251 WeakPolarHBondContact O-CG2 3.5Å; W123-T251 PolarHBondContact O-OG1 3.34Å; Q125-T251 HydrophobicContact CG-CG2 3.79Å; Q125-T251 VanDerWaalsContact NE2-CG2 3.34Å; Q246-T251 PolarHBondContact NE2-OG1 3.27Å; N247-T251 PolarHBondContact O-N 3.01Å; N247-T251 PolarHBondContact O-OG1 3.47Å; T251-W254 PolarHBondContact O-N 3.43Å; T251-L255 HydrophobicContact CG2-CD1 3.97Å; T251-L255 HydrophobicContact CG2-CG 4.42Å; T251-L255 VanDerWaalsContact O-CB 3.3Å; T251-L255 WeakPolarHBondContact O-CB 3.41Å; T251-L255 WeakPolarHBondContact O-CG 3.34Å; T251-L255 PolarHBondContact O-N 2.92Å
252K94.6Very high93.5Very high126 Ų12634.2 Ų34.255%0.54818%0.184SC..Hα-helixtrans-63.2-44.9178.4-172.7178.6-179.6-179.80112.3W123 G248 G249 F250 S256W123-K252 HydrophobicContact CE3-CB 4.34Å; W123-K252 HydrophobicContact CH2-CG 4.4Å; W123-K252 HydrophobicContact CZ3-CB 4Å; W123-K252 HydrophobicContact CZ3-CG 4.28Å; G248-K252 PolarHBondContact O-N 3.46Å; G249-K252 PolarHBondContact O-N 2.76Å; F250-K252 PolarHBondContact O-N 3.41Å; K252-S256 WeakPolarHBondContact O-CB 3.48Å; K252-S256 PolarHBondContact O-N 3.35Å; K252-S256 PolarHBondContact O-OG 3.5Å
253V94.4Very high93.8Very high25 Ų2535.6 Ų35.615%0.15220%0.196CC..Hα-helixtrans-66.3-44.4176.71770000110.6I39 A44 G249 F250 S256 M257I39-V253 HydrophobicContact CG2-CG1 3.61Å; A44-V253 HydrophobicContact CB-CB 3.92Å; A44-V253 HydrophobicContact CB-CG1 3.96Å; A44-V253 HydrophobicContact CB-CG2 3.99Å; G249-V253 PolarHBondContact O-N 2.96Å; F250-V253 PolarHBondContact O-N 3.47Å; F250-V253 VanDerWaalsContact O-N 3.11Å; V253-S256 PolarHBondContact O-N 3.24Å; V253-M257 WeakPolarHBondContact O-CB 3.32Å; V253-M257 PolarHBondContact O-N 3.26Å
254W94.2Very high93.9Very high38 Ų3839.6 Ų39.614%0.14422%0.216CC..Hα-helixtrans-57.8-50.5178.5-171.9-114.2000112.2F250 T251 S256 M257 K258 T499 Y502F250-W254 HydrophobicContact CE1-CB 4.27Å; F250-W254 HydrophobicContact CE1-CD2 4.41Å; F250-W254 HydrophobicContact CE1-CE3 4.44Å; F250-W254 HydrophobicContact CE1-CG 4.36Å; F250-W254 HydrophobicContact CZ-CD2 4.37Å; F250-W254 AromaticContact CZ-CE3 3.95Å; F250-W254 HydrophobicContact CZ-CE3 3.95Å; F250-W254 HydrophobicContact CZ-CZ3 4.49Å; F250-W254 VanDerWaalsContact O-CB 3.31Å; F250-W254 WeakPolarHBondContact O-CB 3.39Å; F250-W254 PolarHBondContact O-N 3.2Å; T251-W254 PolarHBondContact O-N 3.43Å; W254-S256 PolarHBondContact O-N 3.03Å; W254-M257 PolarHBondContact O-N 2.99Å; W254-K258 WeakPolarHBondContact O-CG 3.37Å; W254-K258 PolarHBondContact O-N 2.93Å; W254-T499 HydrophobicContact CE3-CG2 4.47Å; W254-Y502 HydrophobicContact CE3-CD1 4.38Å; W254-Y502 AromaticContact CH2-CD1 3.8Å; W254-Y502 HydrophobicContact CH2-CD1 3.8Å; W254-Y502 HydrophobicContact CH2-CD2 4.21Å; W254-Y502 AromaticContact CH2-CG 3.61Å; W254-Y502 HydrophobicContact CH2-CG 3.61Å; W254-Y502 HydrophobicContact CZ2-CD1 4.41Å; W254-Y502 HydrophobicContact CZ2-CG 4.34Å; W254-Y502 AromaticContact CZ3-CD1 3.78Å; W254-Y502 HydrophobicContact CZ3-CD1 3.78Å; W254-Y502 AromaticContact CZ3-CG 3.95Å; W254-Y502 HydrophobicContact CZ3-CG 3.95Å
255L94.5Very high94.2Very high0 Ų037.3 Ų37.30%020%0.204CC..Hα-helixtrans-62.9-40.2176.5-83.5176.4000112.7W123 T251 M257 K258 T259 P303 E305 W306W123-L255 HydrophobicContact CZ3-CD1 4.02Å; T251-L255 HydrophobicContact CG2-CD1 3.97Å; T251-L255 HydrophobicContact CG2-CG 4.42Å; T251-L255 VanDerWaalsContact O-CB 3.3Å; T251-L255 WeakPolarHBondContact O-CB 3.41Å; T251-L255 WeakPolarHBondContact O-CG 3.34Å; T251-L255 PolarHBondContact O-N 2.92Å; L255-M257 VanDerWaalsContact C-N 3.33Å; L255-M257 PolarHBondContact O-N 2.88Å; L255-K258 PolarHBondContact O-N 3.5Å; L255-T259 WeakPolarHBondContact O-CB 3.26Å; L255-T259 PolarHBondContact O-N 3.46Å; L255-T259 PolarHBondContact O-OG1 3.49Å; L255-P303 HydrophobicContact CD2-CB 4.3Å; L255-E305 HydrophobicContact CD2-CB 3.61Å; L255-E305 HydrophobicContact CD2-CG 4.41Å; L255-E305 HydrophobicContact CG-CB 4.44Å; L255-W306 HydrophobicContact CB-CZ2 3.81Å; L255-W306 HydrophobicContact CD1-CD2 4.03Å; L255-W306 HydrophobicContact CD1-CE3 4.28Å; L255-W306 HydrophobicContact CD1-CG 4.44Å; L255-W306 HydrophobicContact CD1-CZ2 4.39Å; L255-W306 HydrophobicContact CD2-CD2 4.48Å; L255-W306 HydrophobicContact CD2-CG 4.23Å
256S95.1Very high94.5Very high51 Ų5139.4 Ų39.436%0.35722%0.216SC..Hα-helixtrans-62.8-42.2176.8-58.80000111.3K252 V253 W254 T259 I260K252-S256 WeakPolarHBondContact O-CB 3.48Å; K252-S256 PolarHBondContact O-N 3.35Å; K252-S256 PolarHBondContact O-OG 3.5Å; V253-S256 PolarHBondContact O-N 3.24Å; W254-S256 PolarHBondContact O-N 3.03Å; S256-T259 PolarHBondContact O-N 3.31Å; S256-I260 WeakPolarHBondContact O-CG1 3.34Å; S256-I260 PolarHBondContact O-N 2.84Å
257M94.7Very high94.8Very high10 Ų1040.1 Ų40.15%0.04923%0.229CC..Hα-helixtrans-62.8-46.3176.9-174.6174.916700111.3F36 V253 W254 L255 T259 I260 L261 T499 Y502F36-M257 HydrophobicContact CB-CE 4.45Å; F36-M257 HydrophobicContact CD1-CE 3.39Å; F36-M257 HydrophobicContact CD1-SD 4.16Å; F36-M257 HydrophobicContact CE1-CE 3.7Å; F36-M257 HydrophobicContact CG-CE 3.94Å; F36-M257 HydrophobicContact CZ-CE 4.44Å; V253-M257 WeakPolarHBondContact O-CB 3.32Å; V253-M257 PolarHBondContact O-N 3.26Å; W254-M257 PolarHBondContact O-N 2.99Å; L255-M257 VanDerWaalsContact C-N 3.33Å; L255-M257 PolarHBondContact O-N 2.88Å; M257-T259 PolarHBondContact O-N 3.4Å; M257-I260 PolarHBondContact O-N 3.27Å; M257-L261 HydrophobicContact CE-CD1 3.57Å; M257-L261 HydrophobicContact CG-CD1 3.68Å; M257-L261 HydrophobicContact CG-CG 4.43Å; M257-L261 WeakPolarHBondContact O-CB 3.39Å; M257-L261 WeakPolarHBondContact O-CG 3.45Å; M257-L261 PolarHBondContact O-N 2.92Å; M257-T499 WeakPolarHBondContact CE-O 3.28Å; M257-T499 HydrophobicContact SD-CG2 4.4Å; M257-Y502 HydrophobicContact CE-CD1 3.3Å; M257-Y502 HydrophobicContact CE-CE1 3.82Å; M257-Y502 HydrophobicContact CE-CG 4.15Å; M257-Y502 HydrophobicContact CG-CD1 4.19Å; M257-Y502 HydrophobicContact CG-CE1 3.98Å; M257-Y502 HydrophobicContact SD-CD1 3.67Å; M257-Y502 HydrophobicContact SD-CE1 4.09Å
258K96.1Very high95Very high4 Ų439.3 Ų39.32%0.01723%0.227CC..Hα-helixtrans-57.6-47.9173.8-69.4-163.1174.2-164.20112.2W254 L255 I260 L261 F262 I300 P303 E305 Y502W254-K258 WeakPolarHBondContact O-CG 3.37Å; W254-K258 PolarHBondContact O-N 2.93Å; L255-K258 PolarHBondContact O-N 3.5Å; K258-I260 VanDerWaalsContact C-N 3.27Å; K258-I260 PolarHBondContact O-N 2.93Å; K258-L261 PolarHBondContact O-N 3.29Å; K258-F262 VanDerWaalsContact O-CB 3.29Å; K258-F262 WeakPolarHBondContact O-CB 3.41Å; K258-F262 PolarHBondContact O-N 3.27Å; K258-I300 PolarHBondContact NZ-O 3.47Å; K258-P303 HydrophobicContact CB-CB 3.87Å; K258-E305 IonicContact NZ-OE1 3.93Å; K258-E305 PolarHBondContact NZ-OE1 2.93Å; K258-E305 IonicContact NZ-OE2 3.35Å; K258-Y502 HydrophobicContact CG-CE1 4.09Å; K258-Y502 WeakPolarHBondContact CG-OH 3.46Å
259T96.2Very high95.2Very high63 Ų6339.2 Ų39.239%0.38723%0.225SC..Hα-helixtrans-59.3-35.1178.9-60.50000112.8L255 S256 M257 P263 W306L255-T259 WeakPolarHBondContact O-CB 3.26Å; L255-T259 PolarHBondContact O-N 3.46Å; L255-T259 PolarHBondContact O-OG1 3.49Å; S256-T259 PolarHBondContact O-N 3.31Å; M257-T259 PolarHBondContact O-N 3.4Å; T259-P263 WeakPolarHBondContact O-CD 2.98Å; T259-W306 PolarHBondContact OG1-NE1 3.41Å
260I95.6Very high95.4Very high110 Ų11042.2 Ų42.256%0.56423%0.233SC*.Hα-helixtrans-77.1-41.5177.6-67.8167000111.5S256 M257 K258 P263 I264S256-I260 WeakPolarHBondContact O-CG1 3.34Å; S256-I260 PolarHBondContact O-N 2.84Å; M257-I260 PolarHBondContact O-N 3.27Å; K258-I260 VanDerWaalsContact C-N 3.27Å; K258-I260 PolarHBondContact O-N 2.93Å; I260-P263 WeakPolarHBondContact O-CD 3.28Å; I260-P263 WeakPolarHBondContact O-CG 3.27Å; I260-I264 HydrophobicContact CG2-CD1 4.3Å; I260-I264 WeakPolarHBondContact O-CD1 3.26Å; I260-I264 WeakPolarHBondContact O-CG1 3.26Å
261L95.3Very high95.5Very high8 Ų845.9 Ų45.94%0.04225%0.247CC..Hα-helixtrans-74.9-36-176-71.7172.1000113.1F36 M257 K258 I264 M265 Y502 N506F36-L261 HydrophobicContact CE1-CD1 4.33Å; F36-L261 HydrophobicContact CE1-CD2 4.27Å; F36-L261 HydrophobicContact CZ-CD1 4.43Å; F36-L261 HydrophobicContact CZ-CD2 3.84Å; M257-L261 HydrophobicContact CE-CD1 3.57Å; M257-L261 HydrophobicContact CG-CD1 3.68Å; M257-L261 HydrophobicContact CG-CG 4.43Å; M257-L261 WeakPolarHBondContact O-CB 3.39Å; M257-L261 WeakPolarHBondContact O-CG 3.45Å; M257-L261 PolarHBondContact O-N 2.92Å; K258-L261 PolarHBondContact O-N 3.29Å; L261-I264 WeakPolarHBondContact O-CB 3.47Å; L261-I264 PolarHBondContact O-N 2.96Å; L261-I264 VanDerWaalsContact O-N 3.1Å; L261-M265 PolarHBondContact O-N 3.46Å; L261-Y502 HydrophobicContact CD1-CD1 4.47Å; L261-Y502 HydrophobicContact CD1-CE1 3.82Å; L261-N506 HydrophobicContact CD1-CB 4.34Å; L261-N506 HydrophobicContact CD2-CB 4.49Å
262F96.6Very high95.4Very high51 Ų5145.9 Ų45.922%0.22425%0.247CC..Hα-helixtrans-51-54.4179.7178.7-100.8000114.3K258 I264 M265 L266 L298 D301 L302K258-F262 VanDerWaalsContact O-CB 3.29Å; K258-F262 WeakPolarHBondContact O-CB 3.41Å; K258-F262 PolarHBondContact O-N 3.27Å; F262-I264 VanDerWaalsContact C-N 3.28Å; F262-I264 PolarHBondContact O-N 3.21Å; F262-M265 PolarHBondContact O-N 3.46Å; F262-L266 HydrophobicContact CE1-CD2 4.24Å; F262-L266 HydrophobicContact CZ-CD2 4.49Å; F262-L266 VanDerWaalsContact O-CB 3.26Å; F262-L266 WeakPolarHBondContact O-CB 3.35Å; F262-L266 PolarHBondContact O-N 3.47Å; F262-L298 HydrophobicContact CD2-CD1 3.5Å; F262-L298 HydrophobicContact CD2-CG 4.34Å; F262-L298 HydrophobicContact CE2-CD1 3.3Å; F262-L298 HydrophobicContact CE2-CG 3.83Å; F262-L298 HydrophobicContact CG-CD1 4.38Å; F262-L298 HydrophobicContact CZ-CD1 4.04Å; F262-D301 HydrophobicContact CB-CB 4.22Å; F262-D301 HydrophobicContact CD2-CB 4.31Å; F262-L302 HydrophobicContact CD2-CB 4.19Å; F262-L302 HydrophobicContact CD2-CD1 4.14Å; F262-L302 HydrophobicContact CE1-CD1 4.35Å; F262-L302 HydrophobicContact CE2-CB 3.99Å; F262-L302 HydrophobicContact CE2-CD1 3.44Å; F262-L302 VanDerWaalsContact CE2-CD1 3.44Å; F262-L302 HydrophobicContact CE2-CG 4.32Å; F262-L302 HydrophobicContact CZ-CD1 3.58Å
263P96.9Very high95.4Very high69 Ų6946.8 Ų46.845%0.44825%0.247SC..Hα-helixtrans-65.3-31.4179.225.8-35000112.8T259 I260 A267T259-P263 WeakPolarHBondContact O-CD 2.98Å; I260-P263 WeakPolarHBondContact O-CD 3.28Å; I260-P263 WeakPolarHBondContact O-CG 3.27Å; P263-A267 WeakPolarHBondContact O-CB 3.35Å; P263-A267 PolarHBondContact O-N 3Å
264I95.8Very high95.3Very high83 Ų8352.1 Ų52.143%0.42627%0.27SS..Hα-helixtrans-67.2-48.8176.9-61.2171.7000109.9I260 L261 F262 A267 A268 L510I260-I264 HydrophobicContact CG2-CD1 4.3Å; I260-I264 WeakPolarHBondContact O-CD1 3.26Å; I260-I264 WeakPolarHBondContact O-CG1 3.26Å; L261-I264 WeakPolarHBondContact O-CB 3.47Å; L261-I264 PolarHBondContact O-N 2.96Å; L261-I264 VanDerWaalsContact O-N 3.1Å; F262-I264 VanDerWaalsContact C-N 3.28Å; F262-I264 PolarHBondContact O-N 3.21Å; I264-A267 PolarHBondContact O-N 3.36Å; I264-A268 PolarHBondContact O-N 2.96Å; I264-L510 HydrophobicContact CG2-CD1 4.04Å; I264-L510 HydrophobicContact CG2-CD2 4.39Å
265M96.3Very high95.1Very high0 Ų052.6 Ų52.60%027%0.272CS..Hα-helixtrans-63.9-42.7177.2-169.560.566.200111.2L261 F262 A267 A268 V269 M297 L298 N506 T509 L510 L513L261-M265 PolarHBondContact O-N 3.46Å; F262-M265 PolarHBondContact O-N 3.46Å; M265-A267 PolarHBondContact O-N 2.99Å; M265-A268 PolarHBondContact O-N 3.24Å; M265-V269 HydrophobicContact CG-CG2 4.43Å; M265-V269 WeakPolarHBondContact O-CG2 3.5Å; M265-V269 PolarHBondContact O-N 3.29Å; M265-M297 HydrophobicContact CE-CB 4.39Å; M265-M297 HydrophobicContact CE-CG 3.68Å; M265-M297 HydrophobicContact CG-CB 4.49Å; M265-M297 HydrophobicContact CG-CG 4.48Å; M265-M297 HydrophobicContact SD-CB 4.41Å; M265-M297 HydrophobicContact SD-CG 4.32Å; M265-L298 HydrophobicContact CB-CD1 4.37Å; M265-L298 HydrophobicContact CG-CB 4.31Å; M265-L298 HydrophobicContact CG-CD1 4.48Å; M265-N506 HydrophobicContact CE-CB 4.47Å; M265-N506 WeakPolarHBondContact CE-OD1 3.29Å; M265-T509 HydrophobicContact CE-CG2 4.37Å; M265-T509 HydrophobicContact SD-CG2 4.1Å; M265-L510 HydrophobicContact CE-CD1 4.38Å; M265-L510 HydrophobicContact CE-CD2 3.92Å; M265-L510 HydrophobicContact CE-CG 3.68Å; M265-L510 HydrophobicContact SD-CD2 3.83Å; M265-L510 HydrophobicContact SD-CG 4.22Å; M265-L513 HydrophobicContact SD-CD1 4.27Å
266L97.2Very high94.8Very high59 Ų5953.2 Ų53.231%0.30928%0.275SS..Hα-helixtrans-57.8-48.4176.1-179.161.4000111.3F262 A268 V269 L270 L298F262-L266 HydrophobicContact CE1-CD2 4.24Å; F262-L266 HydrophobicContact CZ-CD2 4.49Å; F262-L266 VanDerWaalsContact O-CB 3.26Å; F262-L266 WeakPolarHBondContact O-CB 3.35Å; F262-L266 PolarHBondContact O-N 3.47Å; L266-A268 VanDerWaalsContact C-N 3.32Å; L266-A268 PolarHBondContact O-N 3.25Å; L266-V269 PolarHBondContact O-N 3.43Å; L266-L270 HydrophobicContact CD1-CD1 4.06Å; L266-L270 HydrophobicContact CD1-CG 4.13Å; L266-L270 HydrophobicContact CG-CD1 4Å; L266-L270 HydrophobicContact CG-CG 4.44Å; L266-L270 WeakPolarHBondContact O-CB 3.27Å; L266-L270 VanDerWaalsContact O-CG 3.27Å; L266-L270 WeakPolarHBondContact O-CG 3.49Å; L266-L270 PolarHBondContact O-N 2.87Å; L266-L298 HydrophobicContact CB-CD1 3.76Å; L266-L298 HydrophobicContact CD1-CD1 4.24Å; L266-L298 HydrophobicContact CD1-CD2 3.77Å
267A96.8Very high94.5Very high58 Ų5856.1 Ų56.148%0.47929%0.29SS..Hα-helixtrans-60-42.4177.200000111.6P263 I264 M265 W271P263-A267 WeakPolarHBondContact O-CB 3.35Å; P263-A267 PolarHBondContact O-N 3Å; I264-A267 PolarHBondContact O-N 3.36Å; M265-A267 PolarHBondContact O-N 2.99Å; A267-W271 WeakPolarHBondContact O-CB 3.08Å; A267-W271 PolarHBondContact O-N 3.43Å
268A94.9Very high94.1Very high19 Ų1959.6 Ų59.616%0.15732%0.315CS..Hα-helixtrans-64.6-44177.800000112.6I264 M265 L266 W271 Y272 L510 L513I264-A268 PolarHBondContact O-N 2.96Å; M265-A268 PolarHBondContact O-N 3.24Å; L266-A268 VanDerWaalsContact C-N 3.32Å; L266-A268 PolarHBondContact O-N 3.25Å; A268-W271 PolarHBondContact O-N 3.49Å; A268-Y272 VanDerWaalsContact O-CB 3.29Å; A268-Y272 WeakPolarHBondContact O-CB 3.21Å; A268-Y272 PolarHBondContact O-N 2.94Å; A268-L510 HydrophobicContact CB-CD2 3.39Å; A268-L513 HydrophobicContact CB-CD1 4.24Å
269V95.8Very high93.4Very high10 Ų1061.4 Ų61.46%0.06133%0.325CS..Hα-helixtrans-65.9-44177.8172.20000111.2M265 L266 Y272 R273 F291 L513M265-V269 HydrophobicContact CG-CG2 4.43Å; M265-V269 WeakPolarHBondContact O-CG2 3.5Å; M265-V269 PolarHBondContact O-N 3.29Å; L266-V269 PolarHBondContact O-N 3.43Å; V269-Y272 PolarHBondContact O-N 3.48Å; V269-R273 WeakPolarHBondContact O-CB 3.36Å; V269-R273 PolarHBondContact O-N 3.47Å; V269-F291 HydrophobicContact CG1-CD2 4.26Å; V269-F291 HydrophobicContact CG1-CE2 3.75Å; V269-L513 HydrophobicContact CG2-CD1 3.95Å
270L96.1Very high92.6Very high93 Ų9370.9 Ų70.949%0.48735%0.354SS..Hα-helixtrans-64-43.7176.5-70.5177.3000111.7L266 R273 Q274L266-L270 HydrophobicContact CD1-CD1 4.06Å; L266-L270 HydrophobicContact CD1-CG 4.13Å; L266-L270 HydrophobicContact CG-CD1 4Å; L266-L270 HydrophobicContact CG-CG 4.44Å; L266-L270 WeakPolarHBondContact O-CB 3.27Å; L266-L270 VanDerWaalsContact O-CG 3.27Å; L266-L270 WeakPolarHBondContact O-CG 3.49Å; L266-L270 PolarHBondContact O-N 2.87Å; L270-R273 PolarHBondContact O-N 3.31Å; L270-Q274 WeakPolarHBondContact O-CB 3.43Å; L270-Q274 PolarHBondContact O-N 2.84Å
271W94.3Very high92Very high87 Ų8770 Ų7033%0.3334%0.343SS..Hα-helixtrans-61.5-44.4175.2171.384.7000112I13 A267 A268 Q274 R275 A517I13-W271 HydrophobicContact CD1-CH2 3.72Å; I13-W271 HydrophobicContact CD1-CZ2 4.01Å; A267-W271 WeakPolarHBondContact O-CB 3.08Å; A267-W271 PolarHBondContact O-N 3.43Å; A268-W271 PolarHBondContact O-N 3.49Å; W271-Q274 PolarHBondContact O-N 3.44Å; W271-R275 HydrophobicContact CD2-CG 4.44Å; W271-R275 HydrophobicContact CZ2-CG 4.3Å; W271-R275 WeakPolarHBondContact O-CG 3.43Å; W271-R275 PolarHBondContact O-N 2.96Å; W271-A517 HydrophobicContact CH2-CB 3.29Å; W271-A517 HydrophobicContact CZ2-CB 4.26Å; W271-A517 HydrophobicContact CZ3-CB 3.52Å
272Y93.1Very high91.4Very high0 Ų075 Ų750%038%0.376CS..Hα-helixtrans-63.1-44.3176.9-175-102.7000111.3A268 V269 Q274 R275 L276 E287 L290 F291 L513 A517A268-Y272 VanDerWaalsContact O-CB 3.29Å; A268-Y272 WeakPolarHBondContact O-CB 3.21Å; A268-Y272 PolarHBondContact O-N 2.94Å; V269-Y272 PolarHBondContact O-N 3.48Å; Y272-Q274 PolarHBondContact O-N 3.22Å; Y272-R275 WeakPolarHBondContact O-CB 3.19Å; Y272-R275 PolarHBondContact O-N 3.31Å; Y272-L276 HydrophobicContact CD1-CD1 3.88Å; Y272-L276 HydrophobicContact CD1-CG 4.27Å; Y272-L276 HydrophobicContact CE1-CD1 3.44Å; Y272-L276 VanDerWaalsContact CE1-CD1 3.44Å; Y272-L276 HydrophobicContact CE1-CD2 4.38Å; Y272-L276 HydrophobicContact CE1-CG 3.97Å; Y272-L276 WeakPolarHBondContact O-CG 3.38Å; Y272-L276 PolarHBondContact O-N 2.93Å; Y272-E287 WeakPolarHBondContact OH-CA 3.4Å; Y272-L290 HydrophobicContact CE1-CB 4.3Å; Y272-F291 HydrophobicContact CD1-CB 4.34Å; Y272-F291 HydrophobicContact CD1-CD2 4.32Å; Y272-F291 HydrophobicContact CE1-CB 4.1Å; Y272-L513 HydrophobicContact CD1-CD2 3.82Å; Y272-L513 HydrophobicContact CD2-CB 4.45Å; Y272-L513 HydrophobicContact CD2-CD2 4.13Å; Y272-L513 WeakPolarHBondContact CD2-O 3.31Å; Y272-L513 HydrophobicContact CE1-CD2 4.2Å; Y272-L513 HydrophobicContact CE2-CD2 4.5Å; Y272-L513 HydrophobicContact CG-CD2 3.79Å; Y272-A517 HydrophobicContact CD2-CB 4.03Å; Y272-A517 HydrophobicContact CE2-CB 4.24Å
273R93.3Very high90.7Very high145 Ų14574.7 Ų74.755%0.54738%0.38SS..Hα-helixtrans-58.8-46.8174.7-176.6-178.7174.5-175.6-0.7111.7V269 L270 R275 L276 V277 F291V269-R273 WeakPolarHBondContact O-CB 3.36Å; V269-R273 PolarHBondContact O-N 3.47Å; L270-R273 PolarHBondContact O-N 3.31Å; R273-R275 VanDerWaalsContact C-N 3.27Å; R273-R275 PolarHBondContact O-N 3.3Å; R273-L276 PolarHBondContact O-N 3.39Å; R273-L276 VanDerWaalsContact O-N 3.17Å; R273-V277 HydrophobicContact CG-CG2 4.46Å; R273-V277 WeakPolarHBondContact O-CG2 3.43Å; R273-V277 PolarHBondContact O-N 3.3Å; R273-F291 HydrophobicContact CB-CD2 4.39Å; R273-F291 HydrophobicContact CB-CE2 3.86Å; R273-F291 HydrophobicContact CG-CE2 4.18Å
274Q92.7Very high90.1Very high136 Ų13674 Ų7464%0.63637%0.372SS*.Hα-helixtrans-60.4-39.7178.8-171.6179.57.800111.4L270 W271 Y272 S278L270-Q274 WeakPolarHBondContact O-CB 3.43Å; L270-Q274 PolarHBondContact O-N 2.84Å; W271-Q274 PolarHBondContact O-N 3.44Å; Y272-Q274 PolarHBondContact O-N 3.22Å; Q274-S278 WeakPolarHBondContact O-CB 3.26Å; Q274-S278 PolarHBondContact O-N 2.86Å; Q274-S278 VanDerWaalsContact O-N 3.15Å; Q274-S278 PolarHBondContact O-OG 2.94Å
275R89.5Confident89.7Confident49 Ų4970.9 Ų70.919%0.18536%0.357CS..Hα-helixtrans-62.3-43.4174.1-76-88.7177.5145.1-1112.4W271 Y272 R273 S278 P518 H520W271-R275 HydrophobicContact CD2-CG 4.44Å; W271-R275 HydrophobicContact CZ2-CG 4.3Å; W271-R275 WeakPolarHBondContact O-CG 3.43Å; W271-R275 PolarHBondContact O-N 2.96Å; Y272-R275 WeakPolarHBondContact O-CB 3.19Å; Y272-R275 PolarHBondContact O-N 3.31Å; R273-R275 VanDerWaalsContact C-N 3.27Å; R273-R275 PolarHBondContact O-N 3.3Å; R275-S278 PolarHBondContact O-N 3.04Å; R275-P518 WeakPolarHBondContact CD-O 3.42Å; R275-P518 PolarHBondContact NH1-O 3.13Å; R275-H520 PolarHBondContact NE-NE2 2.62Å; R275-H520 PolarHBondContact NH1-CD2 2.91Å; R275-H520 PolarHBondContact NH2-CD2 3.29Å; R275-H520 VanDerWaalsContact NH2-CD2 3.26Å; R275-H520 PolarHBondContact NH2-NE2 2.96Å
276L88.2Confident89.2Confident12 Ų1272 Ų726%0.06336%0.363CS..Hα-helixtrans-65.4-45.6178.6-69.7-177.9000112.3Y272 R273 S278 L279 E287 P518Y272-L276 HydrophobicContact CD1-CD1 3.88Å; Y272-L276 HydrophobicContact CD1-CG 4.27Å; Y272-L276 HydrophobicContact CE1-CD1 3.44Å; Y272-L276 VanDerWaalsContact CE1-CD1 3.44Å; Y272-L276 HydrophobicContact CE1-CD2 4.38Å; Y272-L276 HydrophobicContact CE1-CG 3.97Å; Y272-L276 WeakPolarHBondContact O-CG 3.38Å; Y272-L276 PolarHBondContact O-N 2.93Å; R273-L276 PolarHBondContact O-N 3.39Å; R273-L276 VanDerWaalsContact O-N 3.17Å; L276-S278 PolarHBondContact O-N 3.45Å; L276-L279 WeakPolarHBondContact O-CB 3.36Å; L276-L279 PolarHBondContact O-N 3.04Å; L276-E287 HydrophobicContact CD1-CB 4.3Å; L276-E287 HydrophobicContact CD2-CB 3.78Å; L276-E287 HydrophobicContact CD2-CG 3.86Å; L276-P518 HydrophobicContact CD2-CG 4.06Å
277V88.6Confident88.8Confident113 Ų11370 Ų7069%0.68535%0.351SS*.Hα-helixtrans-66.9-26.8-179.21750000112.1R273 L279R273-V277 HydrophobicContact CG-CG2 4.46Å; R273-V277 WeakPolarHBondContact O-CG2 3.43Å; R273-V277 PolarHBondContact O-N 3.3Å; V277-L279 PolarHBondContact O-N 3.4Å
278S86.3Confident88.5Confident83 Ų8373 Ų7358%0.5835%0.354SS*.THydrogen-bonded Turntrans-73.6-8.4177.7-58.80000113.8Q274 R275 L276Q274-S278 WeakPolarHBondContact O-CB 3.26Å; Q274-S278 PolarHBondContact O-N 2.86Å; Q274-S278 VanDerWaalsContact O-N 3.15Å; Q274-S278 PolarHBondContact O-OG 2.94Å; R275-S278 PolarHBondContact O-N 3.04Å; L276-S278 PolarHBondContact O-N 3.45Å
279L82.5Confident88.3Confident41 Ų4173 Ų7322%0.21535%0.353CS..SBendtrans-81141.6177.2-64.9176.7000111.1L276 V277 R281 P518L276-L279 WeakPolarHBondContact O-CB 3.36Å; L276-L279 PolarHBondContact O-N 3.04Å; V277-L279 PolarHBondContact O-N 3.4Å; L279-R281 HydrophobicContact CB-CG 4.28Å; L279-R281 HydrophobicContact CD1-CG 4.49Å; L279-R281 PolarHBondContact O-N 3.32Å; L279-P518 HydrophobicContact CD1-CB 3.99Å; L279-P518 HydrophobicContact CD1-CG 3.57Å; L279-P518 HydrophobicContact CD2-CB 3.97Å; L279-P518 HydrophobicContact CD2-CG 4.45Å; L279-P518 HydrophobicContact CG-CB 4.3Å; L279-P518 HydrophobicContact CG-CG 4.24Å
280R80Confident88.2Confident263 Ų26372.7 Ų72.799%0.99235%0.35SS*.SBendtrans-73.9-13.4174.7-67.8-176.5178.5-178.8-3.1113.8
281R81Confident88.1Confident92 Ų9271.6 Ų71.635%0.34734%0.342SS..SBendtrans-97.9154.2-179.270.8169.5-172.3-173.5-0.1110.7L279 L284 E287L279-R281 HydrophobicContact CB-CG 4.28Å; L279-R281 HydrophobicContact CD1-CG 4.49Å; L279-R281 PolarHBondContact O-N 3.32Å; R281-L284 VanDerWaalsContact NH2-CD1 3.26Å; R281-E287 IonicContact CZ-OE1 3.69Å; R281-E287 IonicContact NH2-OE1 3.43Å; R281-E287 PolarHBondContact NH2-OE1 3.17Å
282P83.1Confident88.1Confident113 Ų11370 Ų7073%0.73434%0.344SS*.PPolyproline II helixtrans-62148.8168.227.9-35.2000111
283S81.9Confident88.3Confident43 Ų4370.1 Ų70.130%0.30134%0.344SS..PPolyproline II helixtrans-66134.1178.8-44.40000111.3E287 K288S283-E287 VanDerWaalsContact CA-OE2 3.31Å; S283-E287 WeakPolarHBondContact CA-OE2 3.46Å; S283-K288 VanDerWaalsContact O-CE 3.31Å; S283-K288 WeakPolarHBondContact O-CE 3.16Å
284L85.2Confident88.4Confident55 Ų5563.2 Ų63.229%0.28832%0.318SS..PPolyproline II helixtrans-68.6161.1177.6-64.8170.8000111.3R281 L286 E287 K288 N350R281-L284 VanDerWaalsContact NH2-CD1 3.26Å; L284-L286 VanDerWaalsContact C-N 3.3Å; L284-L286 PolarHBondContact O-N 3.48Å; L284-E287 HydrophobicContact CB-CB 4.49Å; L284-E287 HydrophobicContact CB-CG 4.17Å; L284-E287 PolarHBondContact N-OE2 3.26Å; L284-E287 PolarHBondContact O-N 2.94Å; L284-K288 WeakPolarHBondContact O-CG 3.18Å; L284-K288 PolarHBondContact O-N 2.93Å; L284-K288 VanDerWaalsContact O-N 3.08Å; L284-N350 WeakPolarHBondContact CD2-ND2 3.44Å; L284-N350 WeakPolarHBondContact CD2-OD1 3.24Å
285L86.2Confident88.6Confident18 Ų1858.7 Ų58.79%0.09430%0.304CS..Hα-helixtrans-57.9-44.5178-178.863.5000111.5E287 K288 C289 I337 N350 L352 Y355L285-E287 VanDerWaalsContact C-N 3.33Å; L285-E287 PolarHBondContact O-N 3.4Å; L285-K288 WeakPolarHBondContact O-CB 2.98Å; L285-K288 PolarHBondContact O-N 3.36Å; L285-C289 PolarHBondContact O-N 3.15Å; L285-C289 PolarHBondContact O-SG 2.75Å; L285-C289 VanDerWaalsContact O-SG 3.32Å; L285-I337 HydrophobicContact CD2-CG2 3.88Å; L285-I337 HydrophobicContact CG-CG2 4.02Å; L285-N350 PolarHBondContact N-OD1 2.85Å; L285-L352 HydrophobicContact CD1-CB 4.32Å; L285-L352 HydrophobicContact CD1-CD1 4.22Å; L285-Y355 HydrophobicContact CD2-CD2 3.94Å; L285-Y355 HydrophobicContact CD2-CE2 3.74Å
286L86.2Confident88.9Confident24 Ų2456.9 Ų56.913%0.12630%0.298CS..Hα-helixtrans-61.9-39.2178.7-173.967000112.9L284 K288 C289 L290 F334 F338 Y516L284-L286 VanDerWaalsContact C-N 3.3Å; L284-L286 PolarHBondContact O-N 3.48Å; L286-K288 VanDerWaalsContact C-N 3.34Å; L286-C289 PolarHBondContact O-N 2.99Å; L286-L290 HydrophobicContact CG-CD1 4.33Å; L286-L290 WeakPolarHBondContact O-CB 3.39Å; L286-L290 WeakPolarHBondContact O-CG 3.35Å; L286-L290 PolarHBondContact O-N 3.38Å; L286-F334 HydrophobicContact CD1-CD2 4.33Å; L286-F334 HydrophobicContact CD1-CE2 3.86Å; L286-F338 HydrophobicContact CD1-CB 4.23Å; L286-F338 HydrophobicContact CD1-CD2 3.84Å; L286-F338 HydrophobicContact CD2-CD2 4.21Å; L286-F338 HydrophobicContact CD2-CE2 4.48Å; L286-Y516 HydrophobicContact CD2-CD1 4.17Å; L286-Y516 HydrophobicContact CD2-CE1 4.24Å
287E89Confident89.3Confident15 Ų1556.4 Ų56.47%0.0730%0.296CS..Hα-helixtrans-65.7-39177.6-67.5170171.900111.1Y272 L276 R281 S283 L284 L285 F291Y272-E287 WeakPolarHBondContact OH-CA 3.4Å; L276-E287 HydrophobicContact CD1-CB 4.3Å; L276-E287 HydrophobicContact CD2-CB 3.78Å; L276-E287 HydrophobicContact CD2-CG 3.86Å; R281-E287 IonicContact CZ-OE1 3.69Å; R281-E287 IonicContact NH2-OE1 3.43Å; R281-E287 PolarHBondContact NH2-OE1 3.17Å; S283-E287 VanDerWaalsContact CA-OE2 3.31Å; S283-E287 WeakPolarHBondContact CA-OE2 3.46Å; L284-E287 HydrophobicContact CB-CB 4.49Å; L284-E287 HydrophobicContact CB-CG 4.17Å; L284-E287 PolarHBondContact N-OE2 3.26Å; L284-E287 PolarHBondContact O-N 2.94Å; L285-E287 VanDerWaalsContact C-N 3.33Å; L285-E287 PolarHBondContact O-N 3.4Å; E287-F291 WeakPolarHBondContact O-CB 3.44Å; E287-F291 PolarHBondContact O-N 2.99Å
288K90.8Very high89.7Confident122 Ų12252.5 Ų52.553%0.5327%0.271SS..Hα-helixtrans-65.7-43.2174.2-67.6173.7-179.4174.10111.8S283 L284 L285 L286 F291 C292S283-K288 VanDerWaalsContact O-CE 3.31Å; S283-K288 WeakPolarHBondContact O-CE 3.16Å; L284-K288 WeakPolarHBondContact O-CG 3.18Å; L284-K288 PolarHBondContact O-N 2.93Å; L284-K288 VanDerWaalsContact O-N 3.08Å; L285-K288 WeakPolarHBondContact O-CB 2.98Å; L285-K288 PolarHBondContact O-N 3.36Å; L286-K288 VanDerWaalsContact C-N 3.34Å; K288-F291 PolarHBondContact O-N 3.31Å; K288-C292 WeakPolarHBondContact O-CB 3.37Å; K288-C292 PolarHBondContact O-N 2.97Å
289C91.4Very high90.1Very high20 Ų2051.4 Ų51.414%0.13526%0.258CS..Hα-helixtrans-62.9-42.1176.6-67.90000112.1L285 L286 C292 L293 F334 I337L285-C289 PolarHBondContact O-N 3.15Å; L285-C289 PolarHBondContact O-SG 2.75Å; L285-C289 VanDerWaalsContact O-SG 3.32Å; L286-C289 PolarHBondContact O-N 2.99Å; C289-C292 WeakPolarHBondContact O-CB 3.39Å; C289-C292 PolarHBondContact O-N 2.96Å; C289-L293 PolarHBondContact O-N 3.39Å; C289-F334 HydrophobicContact CB-CD2 4.39Å; C289-I337 WeakPolarHBondContact SG-CD1 3.36Å
290L92.6Very high90.7Very high3 Ų350.2 Ų50.22%0.01625%0.252CS..Hα-helixtrans-64.9-41.1175.7-77.3169.9000112.5Y272 L286 C292 L293 G294 F334 L512 Y516Y272-L290 HydrophobicContact CE1-CB 4.3Å; L286-L290 HydrophobicContact CG-CD1 4.33Å; L286-L290 WeakPolarHBondContact O-CB 3.39Å; L286-L290 WeakPolarHBondContact O-CG 3.35Å; L286-L290 PolarHBondContact O-N 3.38Å; L290-C292 VanDerWaalsContact C-N 3.31Å; L290-C292 PolarHBondContact O-N 3.43Å; L290-L293 PolarHBondContact O-N 2.88Å; L290-G294 PolarHBondContact O-N 3.02Å; L290-F334 HydrophobicContact CD2-CD2 4.16Å; L290-F334 HydrophobicContact CD2-CE2 3.42Å; L290-F334 VanDerWaalsContact CD2-CE2 3.42Å; L290-F334 HydrophobicContact CD2-CZ 3.82Å; L290-F334 HydrophobicContact CG-CD2 4.44Å; L290-F334 HydrophobicContact CG-CE2 3.83Å; L290-L512 HydrophobicContact CD2-CB 3.87Å; L290-L512 HydrophobicContact CD2-CD1 4.09Å; L290-L512 HydrophobicContact CD2-CD2 4.32Å; L290-L512 HydrophobicContact CD2-CG 4.35Å; L290-Y516 HydrophobicContact CD1-CD1 4.33Å; L290-Y516 HydrophobicContact CD1-CG 3.85Å
291F94.3Very high91.5Very high70 Ų7037.7 Ų37.731%0.30721%0.205SC..Hα-helixtrans-60.6-42.5172.9-179.9-106.5000111.4V269 Y272 R273 E287 K288 G294 A295V269-F291 HydrophobicContact CG1-CD2 4.26Å; V269-F291 HydrophobicContact CG1-CE2 3.75Å; Y272-F291 HydrophobicContact CD1-CB 4.34Å; Y272-F291 HydrophobicContact CD1-CD2 4.32Å; Y272-F291 HydrophobicContact CE1-CB 4.1Å; R273-F291 HydrophobicContact CB-CD2 4.39Å; R273-F291 HydrophobicContact CB-CE2 3.86Å; R273-F291 HydrophobicContact CG-CE2 4.18Å; E287-F291 WeakPolarHBondContact O-CB 3.44Å; E287-F291 PolarHBondContact O-N 2.99Å; K288-F291 PolarHBondContact O-N 3.31Å; F291-G294 PolarHBondContact O-N 2.96Å; F291-A295 WeakPolarHBondContact O-CB 3.28Å; F291-A295 PolarHBondContact O-N 2.84Å
292C95.2Very high92.2Very high54 Ų5436.3 Ų36.337%0.36520%0.204SC..Hα-helixtrans-62.9-43.9175.3-168.30000112.2K288 C289 L290 G294 A295 V296 V330K288-C292 WeakPolarHBondContact O-CB 3.37Å; K288-C292 PolarHBondContact O-N 2.97Å; C289-C292 WeakPolarHBondContact O-CB 3.39Å; C289-C292 PolarHBondContact O-N 2.96Å; L290-C292 VanDerWaalsContact C-N 3.31Å; L290-C292 PolarHBondContact O-N 3.43Å; C292-G294 VanDerWaalsContact C-N 3.34Å; C292-G294 PolarHBondContact O-N 2.89Å; C292-A295 PolarHBondContact O-N 3.36Å; C292-V296 WeakPolarHBondContact O-CG2 3.45Å; C292-V296 PolarHBondContact O-N 3.22Å; C292-V330 HydrophobicContact CB-CG1 4.34Å
293L95.9Very high92.7Very high1 Ų132 Ų321%0.00518%0.176CC..Hα-helixtrans-59.8-45.1176.7-176.366.8000111.2C289 L290 V296 M297 F327 V330 L331 F334 T509 L512C289-L293 PolarHBondContact O-N 3.39Å; L290-L293 PolarHBondContact O-N 2.88Å; L293-V296 PolarHBondContact O-N 3.01Å; L293-M297 WeakPolarHBondContact O-CB 3.48Å; L293-M297 PolarHBondContact O-N 2.85Å; L293-F327 HydrophobicContact CD1-CD2 4.21Å; L293-F327 HydrophobicContact CD1-CE2 3.81Å; L293-V330 HydrophobicContact CB-CG1 4.09Å; L293-V330 HydrophobicContact CD1-CG1 4.09Å; L293-L331 HydrophobicContact CD1-CB 4.18Å; L293-L331 HydrophobicContact CD1-CD1 4.18Å; L293-F334 HydrophobicContact CD2-CD1 4.3Å; L293-F334 HydrophobicContact CD2-CG 4.4Å; L293-T509 HydrophobicContact CG-CG2 4.31Å; L293-L512 HydrophobicContact CD2-CD1 3.79Å
294G96.2Very high93.3Very high0 Ų031.3 Ų31.30%017%0.169CC..Hα-helixtrans-63.3-40.3174.900000113.4L290 F291 C292 M297 L298L290-G294 PolarHBondContact O-N 3.02Å; F291-G294 PolarHBondContact O-N 2.96Å; C292-G294 VanDerWaalsContact C-N 3.34Å; C292-G294 PolarHBondContact O-N 2.89Å; G294-M297 PolarHBondContact O-N 3.44Å; G294-L298 WeakPolarHBondContact O-CB 3.46Å; G294-L298 PolarHBondContact O-N 2.94Å
295A96.3Very high93.6Very high41 Ų4129 Ų2934%0.33916%0.156SC..Hα-helixtrans-66.6-37.6177.900000112.8F291 C292 L298 L299F291-A295 WeakPolarHBondContact O-CB 3.28Å; F291-A295 PolarHBondContact O-N 2.84Å; C292-A295 PolarHBondContact O-N 3.36Å; A295-L298 WeakPolarHBondContact O-CB 3.46Å; A295-L299 PolarHBondContact O-N 3.49Å
296V96.7Very high93.9Very high12 Ų1231.6 Ų31.67%0.07317%0.165CC..Hα-helixtrans-74.9-36176.3177.70000111.6C292 L293 L298 L299 I300 L326 F327 V330C292-V296 WeakPolarHBondContact O-CG2 3.45Å; C292-V296 PolarHBondContact O-N 3.22Å; L293-V296 PolarHBondContact O-N 3.01Å; V296-L298 VanDerWaalsContact C-N 3.3Å; V296-L298 PolarHBondContact O-N 3.3Å; V296-L299 WeakPolarHBondContact O-CB 3.43Å; V296-L299 PolarHBondContact O-N 3.44Å; V296-L299 VanDerWaalsContact O-N 3.1Å; V296-I300 PolarHBondContact O-N 2.94Å; V296-I300 VanDerWaalsContact O-N 3.12Å; V296-L326 HydrophobicContact CG1-CB 4.28Å; V296-L326 HydrophobicContact CG1-CD2 4.18Å; V296-L326 HydrophobicContact CG1-CG 3.89Å; V296-L326 HydrophobicContact CG2-CD2 4.03Å; V296-L326 HydrophobicContact CG2-CG 4.03Å; V296-F327 VanDerWaalsContact CG1-CA 3.43Å; V296-F327 HydrophobicContact CG1-CB 3.75Å; V296-F327 HydrophobicContact CG1-CD2 4.42Å; V296-V330 HydrophobicContact CG2-CG2 4.03Å
297M96.1Very high94.3Very high2 Ų234.3 Ų34.31%0.0118%0.179CC..Hα-helixtrans-60.4-43.3171.5-164.267-16000111.3M265 L293 G294 L299 I300 D301 F327 Y502 W505 N506 T509M265-M297 HydrophobicContact CE-CB 4.39Å; M265-M297 HydrophobicContact CE-CG 3.68Å; M265-M297 HydrophobicContact CG-CB 4.49Å; M265-M297 HydrophobicContact CG-CG 4.48Å; M265-M297 HydrophobicContact SD-CB 4.41Å; M265-M297 HydrophobicContact SD-CG 4.32Å; L293-M297 WeakPolarHBondContact O-CB 3.48Å; L293-M297 PolarHBondContact O-N 2.85Å; G294-M297 PolarHBondContact O-N 3.44Å; M297-L299 PolarHBondContact O-N 2.78Å; M297-I300 WeakPolarHBondContact O-CB 3.27Å; M297-I300 PolarHBondContact O-N 3.31Å; M297-I300 VanDerWaalsContact O-N 3.09Å; M297-D301 VanDerWaalsContact O-CG 3.27Å; M297-D301 PolarHBondContact O-N 3.48Å; M297-F327 HydrophobicContact CB-CE2 4.49Å; M297-F327 HydrophobicContact SD-CD2 3.95Å; M297-F327 HydrophobicContact SD-CE2 3.49Å; M297-F327 WeakPolarHBondContact SD-CE2 3.35Å; M297-F327 HydrophobicContact SD-CZ 3.97Å; M297-Y502 HydrophobicContact CE-CD2 4.46Å; M297-Y502 HydrophobicContact CE-CE2 4.08Å; M297-W505 HydrophobicContact CE-CB 4.28Å; M297-N506 HydrophobicContact CE-CB 4.09Å; M297-N506 WeakPolarHBondContact CE-ND2 3.16Å; M297-T509 HydrophobicContact CB-CG2 4.01Å; M297-T509 HydrophobicContact CG-CG2 4.29Å
298L96.2Very high94.4Very high30 Ų3034.1 Ų34.116%0.15718%0.179CC..Hα-helixtrans-57.9-35.4173.4-178.368.8000112.7F262 M265 L266 G294 A295 V296 D301 L302F262-L298 HydrophobicContact CD2-CD1 3.5Å; F262-L298 HydrophobicContact CD2-CG 4.34Å; F262-L298 HydrophobicContact CE2-CD1 3.3Å; F262-L298 HydrophobicContact CE2-CG 3.83Å; F262-L298 HydrophobicContact CG-CD1 4.38Å; F262-L298 HydrophobicContact CZ-CD1 4.04Å; M265-L298 HydrophobicContact CB-CD1 4.37Å; M265-L298 HydrophobicContact CG-CB 4.31Å; M265-L298 HydrophobicContact CG-CD1 4.48Å; L266-L298 HydrophobicContact CB-CD1 3.76Å; L266-L298 HydrophobicContact CD1-CD1 4.24Å; L266-L298 HydrophobicContact CD1-CD2 3.77Å; G294-L298 WeakPolarHBondContact O-CB 3.46Å; G294-L298 PolarHBondContact O-N 2.94Å; A295-L298 WeakPolarHBondContact O-CB 3.46Å; V296-L298 VanDerWaalsContact C-N 3.3Å; V296-L298 PolarHBondContact O-N 3.3Å; L298-D301 PolarHBondContact O-N 3.38Å; L298-L302 PolarHBondContact O-N 3.09Å
299L95.6Very high94.4Very high61 Ų6129.4 Ų29.432%0.31916%0.16SC..Hα-helixtrans-68.9-36.7176.2-178.265.5000112.3A295 V296 M297 L302 R323 L326A295-L299 PolarHBondContact O-N 3.49Å; V296-L299 WeakPolarHBondContact O-CB 3.43Å; V296-L299 PolarHBondContact O-N 3.44Å; V296-L299 VanDerWaalsContact O-N 3.1Å; M297-L299 PolarHBondContact O-N 2.78Å; L299-L302 WeakPolarHBondContact O-CB 3.45Å; L299-R323 HydrophobicContact CD2-CG 4.03Å; L299-R323 HydrophobicContact CG-CG 3.89Å; L299-R323 VanDerWaalsContact O-CD 3.29Å; L299-R323 WeakPolarHBondContact O-CD 3.1Å; L299-L326 HydrophobicContact CD2-CD2 4.1Å
300I95.3Very high94.4Very high16 Ų1636.1 Ų36.18%0.08218%0.182CC..Hα-helixtrans-66.6-44.5173.2-71.7-178.5000111K258 V296 M297 L302 R323 F327 Y502K258-I300 PolarHBondContact NZ-O 3.47Å; V296-I300 PolarHBondContact O-N 2.94Å; V296-I300 VanDerWaalsContact O-N 3.12Å; M297-I300 WeakPolarHBondContact O-CB 3.27Å; M297-I300 PolarHBondContact O-N 3.31Å; M297-I300 VanDerWaalsContact O-N 3.09Å; I300-L302 PolarHBondContact O-N 3.22Å; I300-R323 HydrophobicContact CG1-CB 4.14Å; I300-F327 HydrophobicContact CD1-CB 3.29Å; I300-F327 HydrophobicContact CD1-CD1 4.14Å; I300-F327 HydrophobicContact CD1-CD2 4.18Å; I300-F327 HydrophobicContact CD1-CG 3.63Å; I300-F327 HydrophobicContact CG1-CB 4.38Å; I300-Y502 HydrophobicContact CG2-CE2 3.79Å
301D95.9Very high94.4Very high0 Ų041.8 Ų41.80%021%0.207CC..Hα-helixtrans-71.4-18.4-178-61.7-24.5000112.4F262 M297 L298 P303 Y502 N506F262-D301 HydrophobicContact CB-CB 4.22Å; F262-D301 HydrophobicContact CD2-CB 4.31Å; M297-D301 VanDerWaalsContact O-CG 3.27Å; M297-D301 PolarHBondContact O-N 3.48Å; L298-D301 PolarHBondContact O-N 3.38Å; D301-P303 VanDerWaalsContact O-CD 3.22Å; D301-P303 WeakPolarHBondContact O-CD 3.49Å; D301-P303 VanDerWaalsContact O-N 3.1Å; D301-Y502 WeakPolarHBondContact OD1-CE2 3.46Å; D301-Y502 VanDerWaalsContact OD1-CZ 3.26Å; D301-Y502 PolarHBondContact OD1-OH 2.87Å; D301-N506 PolarHBondContact OD1-ND2 3.49Å; D301-N506 PolarHBondContact OD2-OD1 3.43Å
302L95.4Very high94.1Very high62 Ų6244.7 Ų44.733%0.32522%0.216SC..  trans-60.1113.8176.2-174.570.1000109.4F262 L298 L299 I300 I304 R323F262-L302 HydrophobicContact CD2-CB 4.19Å; F262-L302 HydrophobicContact CD2-CD1 4.14Å; F262-L302 HydrophobicContact CE1-CD1 4.35Å; F262-L302 HydrophobicContact CE2-CB 3.99Å; F262-L302 HydrophobicContact CE2-CD1 3.44Å; F262-L302 VanDerWaalsContact CE2-CD1 3.44Å; F262-L302 HydrophobicContact CE2-CG 4.32Å; F262-L302 HydrophobicContact CZ-CD1 3.58Å; L298-L302 PolarHBondContact O-N 3.09Å; L299-L302 WeakPolarHBondContact O-CB 3.45Å; I300-L302 PolarHBondContact O-N 3.22Å; L302-I304 HydrophobicContact CB-CG2 4.25Å; L302-I304 HydrophobicContact CD2-CG2 3.37Å; L302-I304 HydrophobicContact CG-CG2 3.49Å; L302-I304 VanDerWaalsContact CG-CG2 3.49Å; L302-I304 PolarHBondContact O-N 2.85Å; L302-R323 PolarHBondContact O-NH1 2.98Å; L302-R323 VanDerWaalsContact O-NH1 3.14Å
303P94.9Very high93.9Very high24 Ų2443.5 Ų43.516%0.15621%0.205CC..  trans-85.857.2-169.138.5-38.9000110.3L255 K258 D301 E305 W306L255-P303 HydrophobicContact CD2-CB 4.3Å; K258-P303 HydrophobicContact CB-CB 3.87Å; D301-P303 VanDerWaalsContact O-CD 3.22Å; D301-P303 WeakPolarHBondContact O-CD 3.49Å; D301-P303 VanDerWaalsContact O-N 3.1Å; P303-E305 WeakPolarHBondContact CA-OE2 3.24Å; P303-E305 PolarHBondContact O-N 3.36Å; P303-W306 WeakPolarHBondContact O-CB 3.34Å; P303-W306 VanDerWaalsContact O-CD1 3.26Å; P303-W306 PolarHBondContact O-N 3.28Å
304I93.1Very high93.6Very high28 Ų2845.6 Ų45.614%0.14422%0.219CC..G310 helixtrans-63.8-23-177.478148.1000112L302 W306 L307 M316 F319L302-I304 HydrophobicContact CB-CG2 4.25Å; L302-I304 HydrophobicContact CD2-CG2 3.37Å; L302-I304 HydrophobicContact CG-CG2 3.49Å; L302-I304 VanDerWaalsContact CG-CG2 3.49Å; L302-I304 PolarHBondContact O-N 2.85Å; I304-W306 PolarHBondContact O-N 2.94Å; I304-W306 VanDerWaalsContact O-N 3.11Å; I304-L307 VanDerWaalsContact O-CB 3.27Å; I304-L307 WeakPolarHBondContact O-CB 3.3Å; I304-L307 WeakPolarHBondContact O-CG 3.42Å; I304-L307 PolarHBondContact O-N 2.9Å; I304-M316 HydrophobicContact CD1-CE 3.71Å; I304-M316 HydrophobicContact CD1-SD 3.78Å; I304-M316 HydrophobicContact CG1-CE 3.51Å; I304-M316 HydrophobicContact CG1-SD 3.92Å; I304-F319 HydrophobicContact CD1-CD1 3.31Å; I304-F319 HydrophobicContact CD1-CE1 3.18Å; I304-F319 HydrophobicContact CD1-CG 4.31Å; I304-F319 HydrophobicContact CD1-CZ 4.12Å; I304-F319 HydrophobicContact CG1-CD1 4.18Å; I304-F319 HydrophobicContact CG1-CE1 3.9Å
305E91.9Very high93.4Very high6 Ų649.9 Ų49.93%0.02824%0.238CC..G310 helixtrans-60.3-21.9-179.8-61.374.9174.700111.3L255 K258 P303 L307 S308 M316 R323L255-E305 HydrophobicContact CD2-CB 3.61Å; L255-E305 HydrophobicContact CD2-CG 4.41Å; L255-E305 HydrophobicContact CG-CB 4.44Å; K258-E305 IonicContact NZ-OE1 3.93Å; K258-E305 PolarHBondContact NZ-OE1 2.93Å; K258-E305 IonicContact NZ-OE2 3.35Å; P303-E305 WeakPolarHBondContact CA-OE2 3.24Å; P303-E305 PolarHBondContact O-N 3.36Å; E305-L307 PolarHBondContact O-N 3.24Å; E305-S308 WeakPolarHBondContact O-CB 3.36Å; E305-S308 PolarHBondContact O-N 3.47Å; E305-S308 PolarHBondContact O-OG 3.39Å; E305-M316 HydrophobicContact CB-CE 4.32Å; E305-M316 HydrophobicContact CG-CE 3.4Å; E305-M316 VanDerWaalsContact CG-CE 3.4Å; E305-M316 HydrophobicContact CG-CG 4.49Å; E305-M316 HydrophobicContact CG-SD 4.12Å; E305-R323 IonicContact OE1-CZ 3.14Å; E305-R323 IonicContact OE1-NH1 2.69Å; E305-R323 IonicContact OE1-NH2 3.69Å; E305-R323 PolarHBondContact OE1-NH2 3.02Å; E305-R323 IonicContact OE2-NH1 2.81Å
306W94Very high93.1Very high72 Ų7248.5 Ų48.527%0.27323%0.225SC..G310 helixtrans-52.8-41.5169.3-82.3115.5000111.2W123 L255 T259 P303 I304 S308 L309 W310W123-W306 AromaticContact CH2-CH2 3.76Å; W123-W306 HydrophobicContact CH2-CH2 3.76Å; W123-W306 AromaticContact CH2-CZ3 3.52Å; W123-W306 HydrophobicContact CH2-CZ3 3.52Å; W123-W306 HydrophobicContact CZ2-CZ3 4.34Å; W123-W306 HydrophobicContact CZ3-CH2 4.34Å; W123-W306 HydrophobicContact CZ3-CZ3 4.22Å; L255-W306 HydrophobicContact CB-CZ2 3.81Å; L255-W306 HydrophobicContact CD1-CD2 4.03Å; L255-W306 HydrophobicContact CD1-CE3 4.28Å; L255-W306 HydrophobicContact CD1-CG 4.44Å; L255-W306 HydrophobicContact CD1-CZ2 4.39Å; L255-W306 HydrophobicContact CD2-CD2 4.48Å; L255-W306 HydrophobicContact CD2-CG 4.23Å; T259-W306 PolarHBondContact OG1-NE1 3.41Å; P303-W306 WeakPolarHBondContact O-CB 3.34Å; P303-W306 VanDerWaalsContact O-CD1 3.26Å; P303-W306 PolarHBondContact O-N 3.28Å; I304-W306 PolarHBondContact O-N 2.94Å; I304-W306 VanDerWaalsContact O-N 3.11Å; W306-S308 PolarHBondContact O-N 3.32Å; W306-L309 HydrophobicContact CE3-CD1 3.63Å; W306-L309 HydrophobicContact CZ3-CD1 3.76Å; W306-L309 WeakPolarHBondContact O-CB 3.39Å; W306-L309 PolarHBondContact O-N 3.48Å; W306-W310 HydrophobicContact CB-CZ3 4.06Å; W306-W310 HydrophobicContact CE3-CH2 4.14Å; W306-W310 HydrophobicContact CE3-CZ3 4.33Å; W306-W310 WeakPolarHBondContact O-CZ3 3.48Å
307L93.2Very high92.8Very high81 Ų8149.9 Ų49.942%0.42423%0.231SC..G310 helixtrans-61.1-28.5-179.7-59.9176.2000112.8I304 E305 L309 W310 F311 M313I304-L307 VanDerWaalsContact O-CB 3.27Å; I304-L307 WeakPolarHBondContact O-CB 3.3Å; I304-L307 WeakPolarHBondContact O-CG 3.42Å; I304-L307 PolarHBondContact O-N 2.9Å; E305-L307 PolarHBondContact O-N 3.24Å; L307-L309 PolarHBondContact O-N 3.47Å; L307-W310 PolarHBondContact O-N 3.28Å; L307-W310 VanDerWaalsContact O-N 3.08Å; L307-F311 HydrophobicContact CB-CD2 4.43Å; L307-F311 PolarHBondContact O-N 3.03Å; L307-M313 HydrophobicContact CB-CE 3.47Å; L307-M313 VanDerWaalsContact CB-CE 3.47Å; L307-M313 HydrophobicContact CB-SD 3.89Å; L307-M313 HydrophobicContact CD1-CE 4.03Å; L307-M313 HydrophobicContact CG-CE 4.38Å
308S91.5Very high92.6Very high11 Ų1151.8 Ų51.88%0.07724%0.241CC..G310 helixtrans-63.9-19.8177.173.80000113.5E305 W306 W310 F311E305-S308 WeakPolarHBondContact O-CB 3.36Å; E305-S308 PolarHBondContact O-N 3.47Å; E305-S308 PolarHBondContact O-OG 3.39Å; W306-S308 PolarHBondContact O-N 3.32Å; S308-W310 VanDerWaalsContact C-N 3.33Å; S308-F311 CarbonylContact C-O 3.48Å; S308-F311 WeakPolarHBondContact CA-O 3.36Å
309L91.5Very high92.5Very high23 Ų2353.2 Ų53.212%0.1225%0.247CC..G310 helixtrans-72.8-27.8175.1-59.2-177.9000112.2R122 W123 W306 L307R122-L309 HydrophobicContact CB-CD2 3.99Å; R122-L309 WeakPolarHBondContact CD-O 3.44Å; R122-L309 PolarHBondContact NH1-O 2.96Å; W123-L309 HydrophobicContact CD2-CD1 4.31Å; W123-L309 HydrophobicContact CD2-CD2 4Å; W123-L309 HydrophobicContact CE3-CD1 4.28Å; W123-L309 HydrophobicContact CE3-CD2 4.22Å; W123-L309 HydrophobicContact CG-CD2 4.27Å; W123-L309 HydrophobicContact CH2-CD1 3.66Å; W123-L309 HydrophobicContact CZ2-CD1 3.66Å; W123-L309 HydrophobicContact CZ3-CD1 3.97Å; W306-L309 HydrophobicContact CE3-CD1 3.63Å; W306-L309 HydrophobicContact CZ3-CD1 3.76Å; W306-L309 WeakPolarHBondContact O-CB 3.39Å; W306-L309 PolarHBondContact O-N 3.48Å; L307-L309 PolarHBondContact O-N 3.47Å
310W91Very high92.3Very high161 Ų16151.5 Ų51.561%0.6124%0.239SC*.THydrogen-bonded Turntrans-103-38.3-179.3-65.4-81.1000112.6R122 W306 L307 S308R122-W310 PolarHBondContact NH1-O 3.18Å; W306-W310 HydrophobicContact CB-CZ3 4.06Å; W306-W310 HydrophobicContact CE3-CH2 4.14Å; W306-W310 HydrophobicContact CE3-CZ3 4.33Å; W306-W310 WeakPolarHBondContact O-CZ3 3.48Å; L307-W310 PolarHBondContact O-N 3.28Å; L307-W310 VanDerWaalsContact O-N 3.08Å; S308-W310 VanDerWaalsContact C-N 3.33Å
311F91.3Very high92.1Very high123 Ų12352 Ų5254%0.53924%0.243SC..SBendtrans-115.5142.3-175.1-57-74.1000111.2L307 S308 M313L307-F311 HydrophobicContact CB-CD2 4.43Å; L307-F311 PolarHBondContact O-N 3.03Å; S308-F311 CarbonylContact C-O 3.48Å; S308-F311 WeakPolarHBondContact CA-O 3.36Å; F311-M313 HydrophobicContact CB-CE 3.98Å; F311-M313 HydrophobicContact CB-CG 4.35Å; F311-M313 HydrophobicContact CD2-CE 4.33Å; F311-M313 PolarHBondContact O-N 3.42Å
312R89.4Confident92Very high130 Ų13056 Ų5649%0.49126%0.263SS..  trans-69.2115.2171.9171.6160.4-179.8-160.3-8.2110D210 Y211D210-R312 WeakPolarHBondContact OD1-CA 3.38Å; D210-R312 WeakPolarHBondContact OD2-CD 3.39Å; D210-R312 WeakPolarHBondContact OD2-CG 3.22Å; D210-R312 IonicContact OD2-NE 2.69Å; D210-R312 PolarHBondContact OD2-NE 2.77Å; Y211-R312 PolarHBondContact OH-NH1 2.88Å
313M90.8Very high92Very high29 Ų2953.3 Ų53.314%0.14325%0.249CC..  trans-131.175.8-176.2-67.1-170.6174.500111L307 F311 F315 M316L307-M313 HydrophobicContact CB-CE 3.47Å; L307-M313 VanDerWaalsContact CB-CE 3.47Å; L307-M313 HydrophobicContact CB-SD 3.89Å; L307-M313 HydrophobicContact CD1-CE 4.03Å; L307-M313 HydrophobicContact CG-CE 4.38Å; F311-M313 HydrophobicContact CB-CE 3.98Å; F311-M313 HydrophobicContact CB-CG 4.35Å; F311-M313 HydrophobicContact CD2-CE 4.33Å; F311-M313 PolarHBondContact O-N 3.42Å; M313-F315 HydrophobicContact CB-CE1 4.11Å; M313-F315 HydrophobicContact CB-CZ 4.21Å; M313-F315 HydrophobicContact CG-CE1 4.21Å; M313-F315 HydrophobicContact CG-CZ 4.16Å; M313-F315 PolarHBondContact O-N 2.97Å; M313-F315 VanDerWaalsContact O-N 3.11Å; M313-F315 HydrophobicContact SD-CZ 4.2Å; M313-M316 WeakPolarHBondContact O-CB 3.17Å; M313-M316 PolarHBondContact O-N 3.24Å; M313-M316 VanDerWaalsContact O-N 3.13Å
314P89.2Confident91.9Very high45 Ų4555.6 Ų55.629%0.29226%0.258SS..THydrogen-bonded Turntrans-65.4-17.3-176.426.6-35.4000113.7M316 L381P314-M316 VanDerWaalsContact C-N 3.29Å; P314-M316 PolarHBondContact O-N 3.2Å; P314-L381 HydrophobicContact CB-CD2 4.17Å; P314-L381 HydrophobicContact CG-CD2 4.41Å; P314-L381 WeakPolarHBondContact O-CD2 3.45Å
315F92.2Very high91.9Very high90 Ų9055.9 Ų55.940%0.39527%0.267SS..THydrogen-bonded Turntrans-82.80.3177.465.7-94.9000114.7M313 L317 L318 F319 L381M313-F315 HydrophobicContact CB-CE1 4.11Å; M313-F315 HydrophobicContact CB-CZ 4.21Å; M313-F315 HydrophobicContact CG-CE1 4.21Å; M313-F315 HydrophobicContact CG-CZ 4.16Å; M313-F315 PolarHBondContact O-N 2.97Å; M313-F315 VanDerWaalsContact O-N 3.11Å; M313-F315 HydrophobicContact SD-CZ 4.2Å; F315-L317 VanDerWaalsContact C-N 3.26Å; F315-L317 PolarHBondContact O-N 3.44Å; F315-L318 PolarHBondContact O-N 2.92Å; F315-F319 HydrophobicContact CD2-CB 4.14Å; F315-F319 WeakPolarHBondContact O-CB 3.16Å; F315-F319 PolarHBondContact O-N 2.96Å; F315-L381 HydrophobicContact CB-CD1 4.41Å; F315-L381 HydrophobicContact CB-CD2 3.74Å
316M90.9Very high92.1Very high13 Ų1359.2 Ų59.26%0.06429%0.285CS..Hα-helixtrans-58.7-38.3-173.8-170.264.9-127.800112.5I304 E305 M313 P314 F319 S320 R323I304-M316 HydrophobicContact CD1-CE 3.71Å; I304-M316 HydrophobicContact CD1-SD 3.78Å; I304-M316 HydrophobicContact CG1-CE 3.51Å; I304-M316 HydrophobicContact CG1-SD 3.92Å; E305-M316 HydrophobicContact CB-CE 4.32Å; E305-M316 HydrophobicContact CG-CE 3.4Å; E305-M316 VanDerWaalsContact CG-CE 3.4Å; E305-M316 HydrophobicContact CG-CG 4.49Å; E305-M316 HydrophobicContact CG-SD 4.12Å; M313-M316 WeakPolarHBondContact O-CB 3.17Å; M313-M316 PolarHBondContact O-N 3.24Å; M313-M316 VanDerWaalsContact O-N 3.13Å; P314-M316 VanDerWaalsContact C-N 3.29Å; P314-M316 PolarHBondContact O-N 3.2Å; M316-F319 HydrophobicContact CE-CD1 4.22Å; M316-S320 WeakPolarHBondContact O-CB 3.47Å; M316-S320 PolarHBondContact O-N 3.26Å; M316-R323 VanDerWaalsContact CE-NH2 3.25Å
317L89.5Confident92.1Very high40 Ų4056 Ų5621%0.20927%0.273CS..Hα-helixtrans-63.1-57.4177.7-171.465.9000111.3E205 F315 F319 S320 D321E205-L317 HydrophobicContact CG-CD2 4.37Å; E205-L317 WeakPolarHBondContact OE1-CD2 3.4Å; F315-L317 VanDerWaalsContact C-N 3.26Å; F315-L317 PolarHBondContact O-N 3.44Å; L317-F319 VanDerWaalsContact C-N 3.26Å; L317-F319 PolarHBondContact O-N 3.41Å; L317-S320 WeakPolarHBondContact O-CA 3.5Å; L317-S320 VanDerWaalsContact O-CB 3.29Å; L317-S320 WeakPolarHBondContact O-CB 3.37Å; L317-S320 PolarHBondContact O-N 3.34Å; L317-D321 VanDerWaalsContact O-CG 3.3Å; L317-D321 PolarHBondContact O-N 3.38Å; L317-D321 VanDerWaalsContact O-OD2 3.07Å
318L92.4Very high92.1Very high42 Ų4257.8 Ų57.822%0.2227%0.274CS..Hα-helixtrans-55.7-40.4177.2179.366.2000112.3F315 D321 L322 D373 R377 L381F315-L318 PolarHBondContact O-N 2.92Å; L318-D321 PolarHBondContact O-N 3.25Å; L318-L322 WeakPolarHBondContact O-CB 3.47Å; L318-L322 PolarHBondContact O-N 2.96Å; L318-D373 HydrophobicContact CD1-CB 4.4Å; L318-R377 HydrophobicContact CB-CB 4.49Å; L318-R377 HydrophobicContact CD1-CB 4.21Å; L318-L381 HydrophobicContact CD2-CD1 4.44Å
319F93.2Very high92.3Very high61 Ų6158.1 Ų58.127%0.26828%0.278SS..Hα-helixtrans-68.2-35.1177.3-176.1-98.3000112.4I304 F315 M316 L317 R323I304-F319 HydrophobicContact CD1-CD1 3.31Å; I304-F319 HydrophobicContact CD1-CE1 3.18Å; I304-F319 HydrophobicContact CD1-CG 4.31Å; I304-F319 HydrophobicContact CD1-CZ 4.12Å; I304-F319 HydrophobicContact CG1-CD1 4.18Å; I304-F319 HydrophobicContact CG1-CE1 3.9Å; F315-F319 HydrophobicContact CD2-CB 4.14Å; F315-F319 WeakPolarHBondContact O-CB 3.16Å; F315-F319 PolarHBondContact O-N 2.96Å; M316-F319 HydrophobicContact CE-CD1 4.22Å; L317-F319 VanDerWaalsContact C-N 3.26Å; L317-F319 PolarHBondContact O-N 3.41Å; F319-R323 HydrophobicContact CD1-CG 4.34Å; F319-R323 HydrophobicContact CE1-CG 3.97Å; F319-R323 VanDerWaalsContact CE1-NE 3.3Å; F319-R323 HydrophobicContact CZ-CG 4.15Å; F319-R323 VanDerWaalsContact O-CG 3.3Å; F319-R323 WeakPolarHBondContact O-CG 3.27Å; F319-R323 PolarHBondContact O-N 3.35Å; F319-R323 VanDerWaalsContact O-N 3.15Å; F319-R323 PolarHBondContact O-NE 3.47Å
320S91.1Very high92.4Very high24 Ų2458.1 Ų58.117%0.16828%0.279CS..Hα-helixtrans-63.4-45.9172.8-168.70000111.5M316 L317 L322 R323 Q324M316-S320 WeakPolarHBondContact O-CB 3.47Å; M316-S320 PolarHBondContact O-N 3.26Å; L317-S320 WeakPolarHBondContact O-CA 3.5Å; L317-S320 VanDerWaalsContact O-CB 3.29Å; L317-S320 WeakPolarHBondContact O-CB 3.37Å; L317-S320 PolarHBondContact O-N 3.34Å; S320-L322 PolarHBondContact O-N 2.8Å; S320-R323 PolarHBondContact O-N 3.16Å; S320-Q324 WeakPolarHBondContact O-CG 3.29Å; S320-Q324 PolarHBondContact O-N 3.2Å; S320-Q324 VanDerWaalsContact O-N 3.08Å
321D92.4Very high92.6Very high28 Ų2850.7 Ų50.715%0.1525%0.251CS..Hα-helixtrans-63.6-43.5178.5-52-40.3000111.4L317 L318 R323 Q324 G325 R377L317-D321 VanDerWaalsContact O-CG 3.3Å; L317-D321 PolarHBondContact O-N 3.38Å; L317-D321 VanDerWaalsContact O-OD2 3.07Å; L318-D321 PolarHBondContact O-N 3.25Å; D321-R323 VanDerWaalsContact C-N 3.29Å; D321-R323 PolarHBondContact O-N 3.02Å; D321-Q324 PolarHBondContact O-N 3.43Å; D321-Q324 VanDerWaalsContact O-N 3.15Å; D321-G325 PolarHBondContact O-N 3.42Å; D321-R377 IonicContact OD1-NH1 3.5Å; D321-R377 PolarHBondContact OD1-NH1 3.09Å; D321-R377 WeakPolarHBondContact OD2-CD 3.3Å; D321-R377 IonicContact OD2-CZ 3.82Å; D321-R377 IonicContact OD2-NE 2.75Å; D321-R377 IonicContact OD2-NH1 3.55Å; D321-R377 PolarHBondContact OD2-NH1 3.27Å
322L93.3Very high92.7Very high83 Ų8347.1 Ų47.144%0.43524%0.237SC..Hα-helixtrans-59.6-40.8178.2-174.465.1000111.8L318 S320 L326 F370L318-L322 WeakPolarHBondContact O-CB 3.47Å; L318-L322 PolarHBondContact O-N 2.96Å; S320-L322 PolarHBondContact O-N 2.8Å; L322-L326 VanDerWaalsContact O-CB 3.26Å; L322-L326 WeakPolarHBondContact O-CB 3.48Å; L322-L326 PolarHBondContact O-N 3.44Å; L322-F370 HydrophobicContact CD1-CD2 3.7Å; L322-F370 HydrophobicContact CD1-CE2 3.7Å
323R95Very high92.8Very high5 Ų542.3 Ų42.32%0.01922%0.224CC..Hα-helixtrans-64.7-44176-72.3-176.3-68.1170.73.5111.9L299 I300 L302 E305 M316 F319 S320 D321 F327L299-R323 HydrophobicContact CD2-CG 4.03Å; L299-R323 HydrophobicContact CG-CG 3.89Å; L299-R323 VanDerWaalsContact O-CD 3.29Å; L299-R323 WeakPolarHBondContact O-CD 3.1Å; I300-R323 HydrophobicContact CG1-CB 4.14Å; L302-R323 PolarHBondContact O-NH1 2.98Å; L302-R323 VanDerWaalsContact O-NH1 3.14Å; E305-R323 IonicContact OE1-CZ 3.14Å; E305-R323 IonicContact OE1-NH1 2.69Å; E305-R323 IonicContact OE1-NH2 3.69Å; E305-R323 PolarHBondContact OE1-NH2 3.02Å; E305-R323 IonicContact OE2-NH1 2.81Å; M316-R323 VanDerWaalsContact CE-NH2 3.25Å; F319-R323 HydrophobicContact CD1-CG 4.34Å; F319-R323 HydrophobicContact CE1-CG 3.97Å; F319-R323 VanDerWaalsContact CE1-NE 3.3Å; F319-R323 HydrophobicContact CZ-CG 4.15Å; F319-R323 VanDerWaalsContact O-CG 3.3Å; F319-R323 WeakPolarHBondContact O-CG 3.27Å; F319-R323 PolarHBondContact O-N 3.35Å; F319-R323 VanDerWaalsContact O-N 3.15Å; F319-R323 PolarHBondContact O-NE 3.47Å; S320-R323 PolarHBondContact O-N 3.16Å; D321-R323 VanDerWaalsContact C-N 3.29Å; D321-R323 PolarHBondContact O-N 3.02Å; R323-F327 PolarHBondContact O-N 2.85Å; R323-F327 VanDerWaalsContact O-N 3.11Å
324Q93Very high92.9Very high73 Ų7341 Ų4134%0.34122%0.217SC..Hα-helixtrans-66.6-46.4178.1-69.2-178.71.800111.8S320 D321 L326 F327 Y328S320-Q324 WeakPolarHBondContact O-CG 3.29Å; S320-Q324 PolarHBondContact O-N 3.2Å; S320-Q324 VanDerWaalsContact O-N 3.08Å; D321-Q324 PolarHBondContact O-N 3.43Å; D321-Q324 VanDerWaalsContact O-N 3.15Å; Q324-L326 VanDerWaalsContact C-N 3.31Å; Q324-L326 PolarHBondContact O-N 3.41Å; Q324-F327 WeakPolarHBondContact O-CB 3.4Å; Q324-F327 PolarHBondContact O-N 3.49Å; Q324-F327 VanDerWaalsContact O-N 3.12Å; Q324-Y328 HydrophobicContact CB-CE2 4.25Å; Q324-Y328 WeakPolarHBondContact O-CD2 3.26Å; Q324-Y328 PolarHBondContact O-N 2.91Å
325G93.8Very high93Very high33 Ų3341.1 Ų41.134%0.3421%0.212SC..Hα-helixtrans-58.7-41.2175.600000112.4D321 Y328 A329D321-G325 PolarHBondContact O-N 3.42Å; G325-Y328 PolarHBondContact O-N 2.97Å; G325-A329 WeakPolarHBondContact O-CB 3.34Å; G325-A329 PolarHBondContact O-N 2.95Å
326L95.5Very high92.9Very high77 Ų7736.9 Ų36.940%0.40319%0.193SC..Hα-helixtrans-63.6-41.3174.7-17762.6000112.1V296 L299 L322 Q324 A329 V330V296-L326 HydrophobicContact CG1-CB 4.28Å; V296-L326 HydrophobicContact CG1-CD2 4.18Å; V296-L326 HydrophobicContact CG1-CG 3.89Å; V296-L326 HydrophobicContact CG2-CD2 4.03Å; V296-L326 HydrophobicContact CG2-CG 4.03Å; L299-L326 HydrophobicContact CD2-CD2 4.1Å; L322-L326 VanDerWaalsContact O-CB 3.26Å; L322-L326 WeakPolarHBondContact O-CB 3.48Å; L322-L326 PolarHBondContact O-N 3.44Å; Q324-L326 VanDerWaalsContact C-N 3.31Å; Q324-L326 PolarHBondContact O-N 3.41Å; L326-A329 PolarHBondContact O-N 3.39Å; L326-V330 HydrophobicContact CD1-CG2 4.48Å; L326-V330 WeakPolarHBondContact O-CG2 3.08Å; L326-V330 PolarHBondContact O-N 2.95Å
327F95.2Very high92.7Very high5 Ų536.4 Ų36.42%0.02219%0.191CC..Hα-helixtrans-62.1-46175.1173.7-103.3000111.8L293 V296 M297 I300 R323 Q324 A329 V330 L331 W505L293-F327 HydrophobicContact CD1-CD2 4.21Å; L293-F327 HydrophobicContact CD1-CE2 3.81Å; V296-F327 VanDerWaalsContact CG1-CA 3.43Å; V296-F327 HydrophobicContact CG1-CB 3.75Å; V296-F327 HydrophobicContact CG1-CD2 4.42Å; M297-F327 HydrophobicContact CB-CE2 4.49Å; M297-F327 HydrophobicContact SD-CD2 3.95Å; M297-F327 HydrophobicContact SD-CE2 3.49Å; M297-F327 WeakPolarHBondContact SD-CE2 3.35Å; M297-F327 HydrophobicContact SD-CZ 3.97Å; I300-F327 HydrophobicContact CD1-CB 3.29Å; I300-F327 HydrophobicContact CD1-CD1 4.14Å; I300-F327 HydrophobicContact CD1-CD2 4.18Å; I300-F327 HydrophobicContact CD1-CG 3.63Å; I300-F327 HydrophobicContact CG1-CB 4.38Å; R323-F327 PolarHBondContact O-N 2.85Å; R323-F327 VanDerWaalsContact O-N 3.11Å; Q324-F327 WeakPolarHBondContact O-CB 3.4Å; Q324-F327 PolarHBondContact O-N 3.49Å; Q324-F327 VanDerWaalsContact O-N 3.12Å; F327-A329 VanDerWaalsContact C-N 3.34Å; F327-A329 PolarHBondContact O-N 3.35Å; F327-V330 PolarHBondContact O-N 3.24Å; F327-L331 HydrophobicContact CE1-CD2 4Å; F327-L331 HydrophobicContact CZ-CD2 4.22Å; F327-L331 VanDerWaalsContact O-CB 3.24Å; F327-L331 WeakPolarHBondContact O-CB 3.49Å; F327-L331 PolarHBondContact O-N 2.91Å; F327-W505 HydrophobicContact CE1-CB 4.37Å; F327-W505 HydrophobicContact CE1-CD2 4.17Å; F327-W505 HydrophobicContact CE1-CE3 4.31Å; F327-W505 HydrophobicContact CE1-CG 4.2Å; F327-W505 HydrophobicContact CZ-CB 4.08Å; F327-W505 HydrophobicContact CZ-CD2 4.18Å; F327-W505 AromaticContact CZ-CE3 3.98Å; F327-W505 HydrophobicContact CZ-CE3 3.98Å; F327-W505 HydrophobicContact CZ-CG 4.25Å
328Y92.9Very high92.6Very high117 Ų11735 Ų3546%0.45918%0.183SC..Hα-helixtrans-61-43.6176.6-60-33000111.7Q324 G325 V330 L331 L332Q324-Y328 HydrophobicContact CB-CE2 4.25Å; Q324-Y328 WeakPolarHBondContact O-CD2 3.26Å; Q324-Y328 PolarHBondContact O-N 2.91Å; G325-Y328 PolarHBondContact O-N 2.97Å; Y328-V330 PolarHBondContact O-N 3.47Å; Y328-L331 PolarHBondContact O-N 2.87Å; Y328-L332 WeakPolarHBondContact O-CB 3.34Å; Y328-L332 WeakPolarHBondContact O-CG 3.44Å; Y328-L332 PolarHBondContact O-N 3.34Å
329A94.7Very high92.3Very high19 Ų1933.1 Ų33.116%0.15717%0.174CC..Hα-helixtrans-57.9-46.5176.600000112.2G325 L326 F327 S333 C366G325-A329 WeakPolarHBondContact O-CB 3.34Å; G325-A329 PolarHBondContact O-N 2.95Å; L326-A329 PolarHBondContact O-N 3.39Å; F327-A329 VanDerWaalsContact C-N 3.34Å; F327-A329 PolarHBondContact O-N 3.35Å; A329-S333 VanDerWaalsContact O-CB 3.27Å; A329-S333 WeakPolarHBondContact O-CB 3.45Å; A329-S333 PolarHBondContact O-N 3.11Å; A329-S333 VanDerWaalsContact O-N 3.08Å; A329-S333 PolarHBondContact O-OG 3.45Å; A329-C366 HydrophobicContact CB-CB 4.42Å; A329-C366 VanDerWaalsContact CB-SG 3.57Å
330V95Very high91.8Very high22 Ų2230.4 Ų30.413%0.13316%0.163CC..Hα-helixtrans-70.1-39.2179.5173.70000111.7C292 L293 V296 L326 F327 Y328 S333 F334C292-V330 HydrophobicContact CB-CG1 4.34Å; L293-V330 HydrophobicContact CB-CG1 4.09Å; L293-V330 HydrophobicContact CD1-CG1 4.09Å; V296-V330 HydrophobicContact CG2-CG2 4.03Å; L326-V330 HydrophobicContact CD1-CG2 4.48Å; L326-V330 WeakPolarHBondContact O-CG2 3.08Å; L326-V330 PolarHBondContact O-N 2.95Å; F327-V330 PolarHBondContact O-N 3.24Å; Y328-V330 PolarHBondContact O-N 3.47Å; V330-S333 PolarHBondContact O-N 2.76Å; V330-F334 VanDerWaalsContact O-CB 3.27Å; V330-F334 WeakPolarHBondContact O-CB 3.35Å; V330-F334 PolarHBondContact O-N 2.97Å
331L93.5Very high91.3Very high5 Ų530.6 Ų30.63%0.02616%0.161CC..Hα-helixtrans-64.5-47.9177.8179.566.5000111.9L293 F327 Y328 S333 F334 W335 W505 Y508L293-L331 HydrophobicContact CD1-CB 4.18Å; L293-L331 HydrophobicContact CD1-CD1 4.18Å; F327-L331 HydrophobicContact CE1-CD2 4Å; F327-L331 HydrophobicContact CZ-CD2 4.22Å; F327-L331 VanDerWaalsContact O-CB 3.24Å; F327-L331 WeakPolarHBondContact O-CB 3.49Å; F327-L331 PolarHBondContact O-N 2.91Å; Y328-L331 PolarHBondContact O-N 2.87Å; L331-S333 VanDerWaalsContact C-N 3.32Å; L331-S333 PolarHBondContact O-N 3.12Å; L331-F334 WeakPolarHBondContact O-CB 3.48Å; L331-F334 PolarHBondContact O-N 3.44Å; L331-W335 HydrophobicContact CD1-CZ2 3.88Å; L331-W335 HydrophobicContact CD2-CH2 3.99Å; L331-W335 HydrophobicContact CD2-CZ2 3.86Å; L331-W335 HydrophobicContact CG-CD2 4.49Å; L331-W335 HydrophobicContact CG-CH2 4.2Å; L331-W335 HydrophobicContact CG-CZ2 3.81Å; L331-W335 PolarHBondContact O-N 3.48Å; L331-W505 HydrophobicContact CD1-CZ3 3.93Å; L331-W505 HydrophobicContact CD2-CE3 3.99Å; L331-W505 HydrophobicContact CD2-CH2 3.56Å; L331-W505 HydrophobicContact CD2-CZ2 4.22Å; L331-W505 HydrophobicContact CD2-CZ3 3.42Å; L331-W505 VanDerWaalsContact CD2-CZ3 3.42Å; L331-W505 HydrophobicContact CG-CZ3 4.3Å; L331-Y508 HydrophobicContact CD1-CE1 4Å
332L93.4Very high90.5Very high48 Ų4830.6 Ų30.625%0.25116%0.16SC..Hα-helixtrans-63.7-40178.2-67.2175.6000111.4Y328 W335 L336 V362 Y412Y328-L332 WeakPolarHBondContact O-CB 3.34Å; Y328-L332 WeakPolarHBondContact O-CG 3.44Å; Y328-L332 PolarHBondContact O-N 3.34Å; L332-W335 HydrophobicContact CD2-CE3 3.89Å; L332-W335 HydrophobicContact CD2-CZ3 3.78Å; L332-W335 PolarHBondContact O-N 3.46Å; L332-L336 PolarHBondContact O-N 2.91Å; L332-V362 HydrophobicContact CB-CG1 4.17Å; L332-V362 HydrophobicContact CB-CG2 4.29Å; L332-Y412 WeakPolarHBondContact CA-OH 3.04Å; L332-Y412 HydrophobicContact CB-CE2 3.87Å; L332-Y412 HydrophobicContact CD2-CE1 3.72Å; L332-Y412 HydrophobicContact CD2-CE2 4.39Å; L332-Y412 WeakPolarHBondContact CD2-OH 3.49Å; L332-Y412 PolarHBondContact O-OH 3.12Å; L332-Y412 VanDerWaalsContact O-OH 3.05Å
333S92.6Very high89.4Confident29 Ų2927.5 Ų27.520%0.20314%0.144CC..Hα-helixtrans-63.7-42.2173.8-61.10000111.6A329 V330 L331 W335 L336 I337A329-S333 VanDerWaalsContact O-CB 3.27Å; A329-S333 WeakPolarHBondContact O-CB 3.45Å; A329-S333 PolarHBondContact O-N 3.11Å; A329-S333 VanDerWaalsContact O-N 3.08Å; A329-S333 PolarHBondContact O-OG 3.45Å; V330-S333 PolarHBondContact O-N 2.76Å; L331-S333 VanDerWaalsContact C-N 3.32Å; L331-S333 PolarHBondContact O-N 3.12Å; S333-W335 PolarHBondContact O-N 3.1Å; S333-L336 PolarHBondContact O-N 3.35Å; S333-I337 WeakPolarHBondContact O-CG1 3.34Å; S333-I337 PolarHBondContact O-N 3.45Å
334F92.2Very high87.5Confident2 Ų229.8 Ų29.81%0.00916%0.156CC..Hα-helixtrans-59.3-44.5176164.4-102.2000111.5L286 C289 L290 L293 V330 L331 L336 I337 F338 L455 L512L286-F334 HydrophobicContact CD1-CD2 4.33Å; L286-F334 HydrophobicContact CD1-CE2 3.86Å; C289-F334 HydrophobicContact CB-CD2 4.39Å; L290-F334 HydrophobicContact CD2-CD2 4.16Å; L290-F334 HydrophobicContact CD2-CE2 3.42Å; L290-F334 VanDerWaalsContact CD2-CE2 3.42Å; L290-F334 HydrophobicContact CD2-CZ 3.82Å; L290-F334 HydrophobicContact CG-CD2 4.44Å; L290-F334 HydrophobicContact CG-CE2 3.83Å; L293-F334 HydrophobicContact CD2-CD1 4.3Å; L293-F334 HydrophobicContact CD2-CG 4.4Å; V330-F334 VanDerWaalsContact O-CB 3.27Å; V330-F334 WeakPolarHBondContact O-CB 3.35Å; V330-F334 PolarHBondContact O-N 2.97Å; L331-F334 WeakPolarHBondContact O-CB 3.48Å; L331-F334 PolarHBondContact O-N 3.44Å; F334-L336 PolarHBondContact O-N 2.89Å; F334-I337 PolarHBondContact O-N 3.19Å; F334-F338 HydrophobicContact CE2-CB 4.34Å; F334-F338 HydrophobicContact CE2-CD2 4.38Å; F334-F338 HydrophobicContact CZ-CB 4.35Å; F334-F338 HydrophobicContact CZ-CD2 4.18Å; F334-F338 HydrophobicContact CZ-CG 4.41Å; F334-F338 WeakPolarHBondContact O-CB 3.45Å; F334-F338 PolarHBondContact O-N 3.18Å; F334-L455 HydrophobicContact CE1-CD2 4.09Å; F334-L455 HydrophobicContact CZ-CD2 3.82Å; F334-L512 HydrophobicContact CD1-CD1 4.49Å; F334-L512 HydrophobicContact CE1-CD1 3.62Å; F334-L512 HydrophobicContact CZ-CD1 3.7Å; F334-L512 HydrophobicContact CZ-CD2 4.01Å
335W91.7Very high85.8Confident47 Ų4729.8 Ų29.818%0.17816%0.159CC..Hα-helixtrans-62.7-40.7178.4-68.6-21.9000113.4L331 L332 S333 A339 L416 T459 W505 Y508L331-W335 HydrophobicContact CD1-CZ2 3.88Å; L331-W335 HydrophobicContact CD2-CH2 3.99Å; L331-W335 HydrophobicContact CD2-CZ2 3.86Å; L331-W335 HydrophobicContact CG-CD2 4.49Å; L331-W335 HydrophobicContact CG-CH2 4.2Å; L331-W335 HydrophobicContact CG-CZ2 3.81Å; L331-W335 PolarHBondContact O-N 3.48Å; L332-W335 HydrophobicContact CD2-CE3 3.89Å; L332-W335 HydrophobicContact CD2-CZ3 3.78Å; L332-W335 PolarHBondContact O-N 3.46Å; S333-W335 PolarHBondContact O-N 3.1Å; W335-A339 WeakPolarHBondContact O-CB 3.32Å; W335-A339 PolarHBondContact O-N 2.87Å; W335-L416 HydrophobicContact CB-CD1 4.4Å; W335-T459 HydrophobicContact CD2-CG2 4.24Å; W335-T459 VanDerWaalsContact CE2-CG2 3.42Å; W335-T459 HydrophobicContact CH2-CG2 4.27Å; W335-T459 HydrophobicContact CZ2-CG2 3.44Å; W335-T459 VanDerWaalsContact CZ2-CG2 3.44Å; W335-W505 HydrophobicContact CH2-CH2 4.02Å; W335-W505 AromaticContact CZ2-CH2 3.79Å; W335-W505 HydrophobicContact CZ2-CH2 3.79Å; W335-W505 HydrophobicContact CZ2-CZ3 4.13Å; W335-Y508 PolarHBondContact NE1-OH 2.9Å; W335-Y508 VanDerWaalsContact NE1-OH 3.07Å
336L89.4Confident84Confident1 Ų130.8 Ų30.81%0.00515%0.154CC..Hα-helixtrans-64.5-48.6176.1-73.5172.3000112L332 S333 F334 F338 A339 G340 N358 V362 Y412 L416 L419L332-L336 PolarHBondContact O-N 2.91Å; S333-L336 PolarHBondContact O-N 3.35Å; F334-L336 PolarHBondContact O-N 2.89Å; L336-F338 VanDerWaalsContact C-N 3.32Å; L336-A339 PolarHBondContact O-N 3.39Å; L336-G340 PolarHBondContact O-N 3.03Å; L336-N358 HydrophobicContact CD1-CB 3.97Å; L336-N358 HydrophobicContact CD2-CB 4.44Å; L336-V362 HydrophobicContact CD1-CG2 3.92Å; L336-Y412 HydrophobicContact CD1-CD2 3.68Å; L336-Y412 HydrophobicContact CD1-CE2 3.42Å; L336-Y412 VanDerWaalsContact CD1-CE2 3.42Å; L336-Y412 HydrophobicContact CD2-CD2 4.4Å; L336-Y412 HydrophobicContact CD2-CE2 4.04Å; L336-Y412 HydrophobicContact CG-CD2 4.16Å; L336-Y412 HydrophobicContact CG-CE2 3.52Å; L336-L416 HydrophobicContact CD2-CB 4.24Å; L336-L416 HydrophobicContact CD2-CD1 4.09Å; L336-L419 HydrophobicContact CD2-CD1 3.78Å
337I88.1Confident82Confident4 Ų432.2 Ų32.22%0.02117%0.171CC..Hα-helixtrans-65.7-39.9179.6-65.7169.9000110L285 C289 S333 F334 G340 E341 L352 Y355 L359L285-I337 HydrophobicContact CD2-CG2 3.88Å; L285-I337 HydrophobicContact CG-CG2 4.02Å; C289-I337 WeakPolarHBondContact SG-CD1 3.36Å; S333-I337 WeakPolarHBondContact O-CG1 3.34Å; S333-I337 PolarHBondContact O-N 3.45Å; F334-I337 PolarHBondContact O-N 3.19Å; I337-G340 PolarHBondContact O-N 3.49Å; I337-E341 HydrophobicContact CG2-CG 4.08Å; I337-E341 WeakPolarHBondContact O-CB 3.31Å; I337-E341 WeakPolarHBondContact O-CG 3.48Å; I337-E341 PolarHBondContact O-N 2.88Å; I337-L352 HydrophobicContact CD1-CD1 4.12Å; I337-Y355 HydrophobicContact CG1-CG 4.48Å; I337-L359 HydrophobicContact CD1-CD1 4.32Å; I337-L359 HydrophobicContact CD1-CD2 4.33Å; I337-L359 HydrophobicContact CG1-CD2 4.46Å
338F87Confident80.3Confident10 Ų1035 Ų354%0.04419%0.188CC..Hα-helixtrans-61.4-48.3176.9-180-94.9000111.9L286 F334 L336 G340 H342 F452 L455 Y516L286-F338 HydrophobicContact CD1-CB 4.23Å; L286-F338 HydrophobicContact CD1-CD2 3.84Å; L286-F338 HydrophobicContact CD2-CD2 4.21Å; L286-F338 HydrophobicContact CD2-CE2 4.48Å; F334-F338 HydrophobicContact CE2-CB 4.34Å; F334-F338 HydrophobicContact CE2-CD2 4.38Å; F334-F338 HydrophobicContact CZ-CB 4.35Å; F334-F338 HydrophobicContact CZ-CD2 4.18Å; F334-F338 HydrophobicContact CZ-CG 4.41Å; F334-F338 WeakPolarHBondContact O-CB 3.45Å; F334-F338 PolarHBondContact O-N 3.18Å; L336-F338 VanDerWaalsContact C-N 3.32Å; F338-G340 VanDerWaalsContact C-N 3.31Å; F338-G340 PolarHBondContact O-N 3.49Å; F338-H342 AromaticContact CD2-CE1 3.67Å; F338-H342 AromaticContact CD2-ND1 4Å; F338-H342 AromaticContact CE2-CE1 3.15Å; F338-H342 WeakPolarHBondContact CE2-CE1 3.47Å; F338-H342 AromaticContact CE2-ND1 3.81Å; F338-H342 AromaticContact CE2-NE2 3.95Å; F338-H342 AromaticContact CZ-CE1 3.37Å; F338-H342 WeakPolarHBondContact CZ-CE1 3.49Å; F338-H342 AromaticContact CZ-ND1 3.83Å; F338-H342 AromaticContact CZ-NE2 3.87Å; F338-H342 PolarHBondContact O-N 3.35Å; F338-H342 PolarHBondContact O-ND1 3.36Å; F338-F452 HydrophobicContact CD1-CD2 4.27Å; F338-F452 HydrophobicContact CD1-CE2 4.4Å; F338-F452 AromaticContact CE1-CD2 3.53Å; F338-F452 HydrophobicContact CE1-CD2 3.53Å; F338-F452 HydrophobicContact CE1-CE2 4.03Å; F338-F452 HydrophobicContact CE1-CG 4.49Å; F338-F452 HydrophobicContact CZ-CD2 4.19Å; F338-L455 HydrophobicContact CD1-CD2 3.85Å; F338-L455 HydrophobicContact CD2-CD2 3.69Å; F338-L455 HydrophobicContact CE1-CB 4.08Å; F338-L455 HydrophobicContact CE1-CD2 3.57Å; F338-L455 HydrophobicContact CE1-CG 4.2Å; F338-L455 HydrophobicContact CE2-CD2 3.39Å; F338-L455 HydrophobicContact CG-CD2 3.92Å; F338-L455 HydrophobicContact CZ-CB 3.83Å; F338-L455 HydrophobicContact CZ-CD2 3.34Å; F338-L455 HydrophobicContact CZ-CG 4.12Å; F338-Y516 AromaticContact CE2-CE1 3.85Å; F338-Y516 HydrophobicContact CE2-CE1 3.85Å; F338-Y516 AromaticContact CE2-CZ 3.68Å; F338-Y516 WeakPolarHBondContact CE2-OH 3.18Å; F338-Y516 VanDerWaalsContact CZ-OH 3.31Å; F338-Y516 WeakPolarHBondContact CZ-OH 3.32Å
339A85.2Confident78.9Confident2 Ų232.4 Ų32.42%0.01718%0.179CC..Hα-helixtrans-62.9-4117600000111.5W335 L336 H342 L419 L420 V423W335-A339 WeakPolarHBondContact O-CB 3.32Å; W335-A339 PolarHBondContact O-N 2.87Å; L336-A339 PolarHBondContact O-N 3.39Å; A339-H342 PolarHBondContact O-N 3.05Å; A339-L419 HydrophobicContact CB-CB 4.3Å; A339-L420 HydrophobicContact CB-CD2 4.41Å; A339-V423 VanDerWaalsContact O-CG2 3.25Å; A339-V423 WeakPolarHBondContact O-CG2 3.5Å
340G82.6Confident77.7Confident4 Ų435.2 Ų35.24%0.04119%0.192CC..Hα-helixtrans-61.8-49.6177.800000114.3L336 I337 F338 H342 L343 Y355L336-G340 PolarHBondContact O-N 3.03Å; I337-G340 PolarHBondContact O-N 3.49Å; F338-G340 VanDerWaalsContact C-N 3.31Å; F338-G340 PolarHBondContact O-N 3.49Å; G340-H342 PolarHBondContact O-N 3.31Å; G340-L343 VanDerWaalsContact O-CB 3.27Å; G340-L343 WeakPolarHBondContact O-CB 3.26Å; G340-L343 PolarHBondContact O-N 3.16Å; G340-Y355 VanDerWaalsContact C-OH 3.24Å
341E80.2Confident76.8Confident29 Ų2938.6 Ų38.614%0.13621%0.209CC..Hα-helixtrans-66.5-22.5-178.1-73.4-66.9131.900113I337 L343 N350 Y355I337-E341 HydrophobicContact CG2-CG 4.08Å; I337-E341 WeakPolarHBondContact O-CB 3.31Å; I337-E341 WeakPolarHBondContact O-CG 3.48Å; I337-E341 PolarHBondContact O-N 2.88Å; E341-L343 VanDerWaalsContact C-N 3.35Å; E341-N350 PolarHBondContact OE1-N 3.1Å; E341-N350 VanDerWaalsContact OE1-N 3.1Å; E341-Y355 PolarHBondContact N-OH 3.33Å; E341-Y355 WeakPolarHBondContact OE1-CE2 3.47Å; E341-Y355 PolarHBondContact OE1-OH 2.96Å
342H76.3Confident76.1Confident28 Ų2842.7 Ų42.713%0.1323%0.231CC..THydrogen-bonded Turntrans-84.7-6.2173.6-71.278.9000113.4F338 A339 G340 I344 V423 F452F338-H342 AromaticContact CD2-CE1 3.67Å; F338-H342 AromaticContact CD2-ND1 4Å; F338-H342 AromaticContact CE2-CE1 3.15Å; F338-H342 WeakPolarHBondContact CE2-CE1 3.47Å; F338-H342 AromaticContact CE2-ND1 3.81Å; F338-H342 AromaticContact CE2-NE2 3.95Å; F338-H342 AromaticContact CZ-CE1 3.37Å; F338-H342 WeakPolarHBondContact CZ-CE1 3.49Å; F338-H342 AromaticContact CZ-ND1 3.83Å; F338-H342 AromaticContact CZ-NE2 3.87Å; F338-H342 PolarHBondContact O-N 3.35Å; F338-H342 PolarHBondContact O-ND1 3.36Å; A339-H342 PolarHBondContact O-N 3.05Å; G340-H342 PolarHBondContact O-N 3.31Å; H342-I344 PolarHBondContact O-N 3.45Å; H342-V423 HydrophobicContact CB-CG1 4.48Å; H342-F452 HydrophobicContact CB-CD2 3.79Å; H342-F452 HydrophobicContact CB-CE2 4.28Å; H342-F452 HydrophobicContact CB-CG 4.41Å; H342-F452 AromaticContact CG-CD2 3.74Å
343L70.8Confident75.5Confident17 Ų1749.1 Ų49.19%0.08925%0.253CS..SBendtrans-69.3130.5163.7-67.6165.3000108.2G340 E341 D345 K349 L419 R422 V423G340-L343 VanDerWaalsContact O-CB 3.27Å; G340-L343 WeakPolarHBondContact O-CB 3.26Å; G340-L343 PolarHBondContact O-N 3.16Å; E341-L343 VanDerWaalsContact C-N 3.35Å; L343-D345 PolarHBondContact O-N 3.48Å; L343-K349 WeakPolarHBondContact O-CE 3.42Å; L343-K349 PolarHBondContact O-NZ 3.43Å; L343-L419 HydrophobicContact CD1-CD2 3.74Å; L343-R422 HydrophobicContact CD2-CB 3.87Å; L343-V423 HydrophobicContact CD2-CB 4.24Å; L343-V423 HydrophobicContact CD2-CG2 3.47Å; L343-V423 VanDerWaalsContact CD2-CG2 3.47Å; L343-V423 HydrophobicContact CG-CG2 3.64Å
344I54.5Low74.7Confident54 Ų5449.7 Ų49.728%0.27726%0.259SS..  trans-70.5-17.5-173.1-65.5177.2000111.6H342 E346 K349 T426 T430 F445H342-I344 PolarHBondContact O-N 3.45Å; I344-E346 PolarHBondContact O-N 3.02Å; I344-K349 PolarHBondContact O-NZ 3.47Å; I344-K349 VanDerWaalsContact O-NZ 3.08Å; I344-T426 HydrophobicContact CB-CG2 4.05Å; I344-T426 HydrophobicContact CD1-CG2 3.68Å; I344-T426 HydrophobicContact CG1-CG2 3.84Å; I344-T430 HydrophobicContact CD1-CG2 4.1Å; I344-T430 WeakPolarHBondContact CD1-OG1 3.44Å; I344-F445 HydrophobicContact CD1-CE1 4.19Å
345D58Low74.2Confident73 Ų7350.1 Ų50.139%0.3926%0.261SS..  trans-57.9119.7-179.7-123.6-22.1000111.9L343 R422L343-D345 PolarHBondContact O-N 3.48Å; D345-R422 IonicContact OD2-NH2 3.88Å
346E54.7Low73.8Confident53 Ų5355.3 Ų55.325%0.24828%0.281CS..  trans-83.6-22.4-169.6-71.1-149.1121.600114.8I344 T348 K349 M554 S555I344-E346 PolarHBondContact O-N 3.02Å; E346-T348 PolarHBondContact O-N 2.87Å; E346-K349 PolarHBondContact O-N 2.81Å; E346-M554 HydrophobicContact CG-CB 4.21Å; E346-M554 WeakPolarHBondContact OE1-CB 3.4Å; E346-M554 WeakPolarHBondContact OE2-CB 3.37Å; E346-S555 WeakPolarHBondContact OE2-CA 3.19Å; E346-S555 WeakPolarHBondContact OE2-CB 3.15Å; E346-S555 PolarHBondContact OE2-N 3.2Å; E346-S555 PolarHBondContact OE2-OG 2.86Å
347S54.8Low73.4Confident107 Ų10763.1 Ų63.175%0.74831%0.314SS*.THydrogen-bonded Turntrans-65.4-14.4-167.457.30000114.2
348T58.8Low73.1Confident63 Ų6364.2 Ų64.239%0.38732%0.32SS..THydrogen-bonded Turntrans-123.83.2-174.252.90000114.7E346 A354E346-T348 PolarHBondContact O-N 2.87Å; T348-A354 HydrophobicContact CG2-CB 3.89Å
349K63.8Low73.1Confident63 Ų6364.9 Ų64.927%0.27432%0.324SS..THydrogen-bonded Turntrans-70.7144.1-171.6-76.3-177.4168.51630113.2L343 I344 E346 N351L343-K349 WeakPolarHBondContact O-CE 3.42Å; L343-K349 PolarHBondContact O-NZ 3.43Å; I344-K349 PolarHBondContact O-NZ 3.47Å; I344-K349 VanDerWaalsContact O-NZ 3.08Å; E346-K349 PolarHBondContact O-N 2.81Å; K349-N351 PolarHBondContact O-N 3.24Å; K349-N351 VanDerWaalsContact O-N 3.09Å
350N69.9Low73.4Confident78 Ų7867 Ų6742%0.41734%0.339SS..THydrogen-bonded Turntrans62.62.5178.9-69-52.4000117L284 L285 E341L284-N350 WeakPolarHBondContact CD2-ND2 3.44Å; L284-N350 WeakPolarHBondContact CD2-OD1 3.24Å; L285-N350 PolarHBondContact N-OD1 2.85Å; E341-N350 PolarHBondContact OE1-N 3.1Å; E341-N350 VanDerWaalsContact OE1-N 3.1Å
351N74.8Confident73.8Confident93 Ų9367.4 Ų67.450%0.49734%0.342SS..  trans-104.6113.9176.3-163.8-6.1000110.7K349 Y353 A354K349-N351 PolarHBondContact O-N 3.24Å; K349-N351 VanDerWaalsContact O-N 3.09Å; N351-Y353 PolarHBondContact O-N 2.89Å; N351-Y353 PolarHBondContact OD1-N 3.4Å; N351-A354 WeakPolarHBondContact O-CB 3.13Å; N351-A354 PolarHBondContact O-N 3.18Å; N351-A354 VanDerWaalsContact O-N 3.08Å
352L78.9Confident74.4Confident92 Ų9266.4 Ų66.448%0.48234%0.338SS..G310 helixtrans-57.3-33.6178.1-174.268.3000111.7L285 I337 A354 Y355 W356 L359L285-L352 HydrophobicContact CD1-CB 4.32Å; L285-L352 HydrophobicContact CD1-CD1 4.22Å; I337-L352 HydrophobicContact CD1-CD1 4.12Å; L352-A354 PolarHBondContact O-N 3.24Å; L352-Y355 PolarHBondContact O-N 3.22Å; L352-W356 PolarHBondContact O-N 2.85Å; L352-L359 HydrophobicContact CD1-CD1 3.5Å; L352-L359 VanDerWaalsContact CD1-CD1 3.5Å; L352-L359 HydrophobicContact CG-CD1 4.28Å
353Y80.8Confident75.3Confident182 Ų18271.2 Ų71.271%0.71436%0.358SS*.G310 helixtrans-60-31179.8-170.7-100.6000112.7N351 Y355 W356N351-Y353 PolarHBondContact O-N 2.89Å; N351-Y353 PolarHBondContact OD1-N 3.4Å; Y353-Y355 PolarHBondContact O-N 2.74Å; Y353-W356 VanDerWaalsContact O-CB 3.3Å; Y353-W356 WeakPolarHBondContact O-CB 3.16Å; Y353-W356 PolarHBondContact O-N 3.16Å
354A76.9Confident76.3Confident41 Ų4173.1 Ų73.134%0.33937%0.373SS..G310 helixtrans-65.8-26.7177.200000112.8T348 N351 L352T348-A354 HydrophobicContact CG2-CB 3.89Å; N351-A354 WeakPolarHBondContact O-CB 3.13Å; N351-A354 PolarHBondContact O-N 3.18Å; N351-A354 VanDerWaalsContact O-N 3.08Å; L352-A354 PolarHBondContact O-N 3.24Å
355Y80.4Confident78.2Confident12 Ų1270.8 Ų70.85%0.04736%0.363CS..G310 helixtrans-93.31.1178.6-60-73.8000113.6L285 I337 G340 E341 L352 Y353 K357 N358 L359L285-Y355 HydrophobicContact CD2-CD2 3.94Å; L285-Y355 HydrophobicContact CD2-CE2 3.74Å; I337-Y355 HydrophobicContact CG1-CG 4.48Å; G340-Y355 VanDerWaalsContact C-OH 3.24Å; E341-Y355 PolarHBondContact N-OH 3.33Å; E341-Y355 WeakPolarHBondContact OE1-CE2 3.47Å; E341-Y355 PolarHBondContact OE1-OH 2.96Å; L352-Y355 PolarHBondContact O-N 3.22Å; Y353-Y355 PolarHBondContact O-N 2.74Å; Y355-K357 PolarHBondContact O-N 2.9Å; Y355-K357 VanDerWaalsContact O-N 3.15Å; Y355-N358 PolarHBondContact O-N 3Å; Y355-L359 WeakPolarHBondContact O-CG 3.33Å; Y355-L359 PolarHBondContact O-N 3.33Å
356W83.4Confident80Confident156 Ų15669.2 Ų69.259%0.59136%0.357SS*.Hα-helixtrans-53.4-40.3-174.8176.4-103.6000112.9L352 Y353 N358 L359 S360L352-W356 PolarHBondContact O-N 2.85Å; Y353-W356 VanDerWaalsContact O-CB 3.3Å; Y353-W356 WeakPolarHBondContact O-CB 3.16Å; Y353-W356 PolarHBondContact O-N 3.16Å; W356-N358 PolarHBondContact O-N 3.45Å; W356-L359 PolarHBondContact O-N 3.44Å; W356-S360 VanDerWaalsContact O-CB 3.24Å; W356-S360 WeakPolarHBondContact O-CB 3.47Å; W356-S360 PolarHBondContact O-N 3.45Å
357K81.6Confident81.9Confident164 Ų16470.2 Ų70.271%0.71336%0.364SS*.Hα-helixtrans-59.2-46.1177.2-66.5-177-179.3179.20111.9Y355 S360Y355-K357 PolarHBondContact O-N 2.9Å; Y355-K357 VanDerWaalsContact O-N 3.15Å; K357-S360 PolarHBondContact O-OG 3.08Å
358N80.7Confident83.9Confident28 Ų2865.7 Ų65.715%0.1533%0.332CS..Hα-helixtrans-72.3-39.9-178.8-56.3-20.9000111.3L336 Y355 W356 S360 A361L336-N358 HydrophobicContact CD1-CB 3.97Å; L336-N358 HydrophobicContact CD2-CB 4.44Å; Y355-N358 PolarHBondContact O-N 3Å; W356-N358 PolarHBondContact O-N 3.45Å; N358-S360 VanDerWaalsContact C-N 3.33Å; N358-A361 PolarHBondContact O-N 3.27Å
359L88.4Confident85.6Confident23 Ų2366.4 Ų66.412%0.1233%0.333CS..Hα-helixtrans-72.3-26.8179.6-66.2173.6000112.6I337 L352 Y355 W356 A361 V362 F363I337-L359 HydrophobicContact CD1-CD1 4.32Å; I337-L359 HydrophobicContact CD1-CD2 4.33Å; I337-L359 HydrophobicContact CG1-CD2 4.46Å; L352-L359 HydrophobicContact CD1-CD1 3.5Å; L352-L359 VanDerWaalsContact CD1-CD1 3.5Å; L352-L359 HydrophobicContact CG-CD1 4.28Å; Y355-L359 WeakPolarHBondContact O-CG 3.33Å; Y355-L359 PolarHBondContact O-N 3.33Å; W356-L359 PolarHBondContact O-N 3.44Å; L359-A361 PolarHBondContact O-N 2.93Å; L359-V362 PolarHBondContact O-N 3.49Å; L359-F363 WeakPolarHBondContact O-CB 3.37Å; L359-F363 PolarHBondContact O-N 2.95Å
360S90.4Very high87Confident48 Ų4868.3 Ų68.334%0.33634%0.341SS..Hα-helixtrans-61.5-33.9176.972.40000112.4W356 K357 N358 S364W356-S360 VanDerWaalsContact O-CB 3.24Å; W356-S360 WeakPolarHBondContact O-CB 3.47Å; W356-S360 PolarHBondContact O-N 3.45Å; K357-S360 PolarHBondContact O-OG 3.08Å; N358-S360 VanDerWaalsContact C-N 3.33Å; S360-S364 VanDerWaalsContact O-CB 3.24Å; S360-S364 WeakPolarHBondContact O-CB 3.21Å; S360-S364 PolarHBondContact O-N 3.38Å
361A91.5Very high88.2Confident11 Ų1167.3 Ų67.39%0.09134%0.335CS..Hα-helixtrans-64.6-46.6175.100000111.3N358 L359 G365 S408 V411N358-A361 PolarHBondContact O-N 3.27Å; L359-A361 PolarHBondContact O-N 2.93Å; A361-G365 PolarHBondContact O-N 3.39Å; A361-S408 WeakPolarHBondContact O-CB 3.33Å; A361-V411 HydrophobicContact CB-CG1 4.13Å
362V93.5Very high89.1Confident9 Ų963.9 Ų63.96%0.05532%0.316CS..Hα-helixtrans-63.1-48.1176.5-177.40000110.6L332 L336 L359 S364 G365 C366 Y412L332-V362 HydrophobicContact CB-CG1 4.17Å; L332-V362 HydrophobicContact CB-CG2 4.29Å; L336-V362 HydrophobicContact CD1-CG2 3.92Å; L359-V362 PolarHBondContact O-N 3.49Å; V362-S364 PolarHBondContact O-N 3.21Å; V362-G365 PolarHBondContact O-N 3.5Å; V362-C366 WeakPolarHBondContact O-CB 3.46Å; V362-C366 PolarHBondContact O-N 2.86Å; V362-C366 PolarHBondContact O-SG 3.27Å; V362-Y412 HydrophobicContact CG2-CD2 3.44Å; V362-Y412 VanDerWaalsContact CG2-CD2 3.44Å; V362-Y412 HydrophobicContact CG2-CE2 3.69Å
363F93.9Very high89.8Confident128 Ų12861.6 Ų61.656%0.56130%0.304SS*.Hα-helixtrans-60.1-46.9-179.9179-99.3000111.9L359 G365 C366 L367L359-F363 WeakPolarHBondContact O-CB 3.37Å; L359-F363 PolarHBondContact O-N 2.95Å; F363-G365 PolarHBondContact O-N 3.37Å; F363-C366 PolarHBondContact O-N 3.21Å; F363-L367 HydrophobicContact CE1-CD2 4.06Å; F363-L367 HydrophobicContact CZ-CD2 4.38Å; F363-L367 WeakPolarHBondContact O-CB 3.13Å; F363-L367 PolarHBondContact O-N 3.32Å
364S93.6Very high90.3Very high57 Ų5754.8 Ų54.840%0.39929%0.286SS..Hα-helixtrans-61.3-44178.1-1720000111.7S360 V362 L367 C368S360-S364 VanDerWaalsContact O-CB 3.24Å; S360-S364 WeakPolarHBondContact O-CB 3.21Å; S360-S364 PolarHBondContact O-N 3.38Å; V362-S364 PolarHBondContact O-N 3.21Å; S364-L367 PolarHBondContact O-N 3.34Å; S364-C368 PolarHBondContact O-N 2.85Å; S364-C368 PolarHBondContact O-SG 2.92Å
365G94.1Very high91.1Very high6 Ų655.2 Ų55.26%0.06229%0.286CS..Hα-helixtrans-63.6-49178.600000112.9A361 V362 F363 L367 C368 L369 S408A361-G365 PolarHBondContact O-N 3.39Å; V362-G365 PolarHBondContact O-N 3.5Å; F363-G365 PolarHBondContact O-N 3.37Å; G365-L367 VanDerWaalsContact C-N 3.31Å; G365-L367 PolarHBondContact O-N 2.98Å; G365-C368 PolarHBondContact O-N 3.29Å; G365-L369 WeakPolarHBondContact O-CG 3.37Å; G365-L369 PolarHBondContact O-N 3.1Å; G365-S408 WeakPolarHBondContact CA-OG 3.4Å
366C95.1Very high91.6Very high39 Ų3955.9 Ų55.926%0.26429%0.289SS..Hα-helixtrans-64-36.2177.4-65.90000112.2A329 V362 F363 L369 F370A329-C366 HydrophobicContact CB-CB 4.42Å; A329-C366 VanDerWaalsContact CB-SG 3.57Å; V362-C366 WeakPolarHBondContact O-CB 3.46Å; V362-C366 PolarHBondContact O-N 2.86Å; V362-C366 PolarHBondContact O-SG 3.27Å; F363-C366 PolarHBondContact O-N 3.21Å; C366-L369 PolarHBondContact O-N 2.83Å; C366-F370 WeakPolarHBondContact O-CB 3.18Å; C366-F370 PolarHBondContact O-N 3.21Å
367L95.1Very high91.9Very high75 Ų7551.6 Ų51.639%0.39327%0.273SS..Hα-helixtrans-65.7-42.9175.8-178.862.9000111.5F363 S364 G365 F370 I371F363-L367 HydrophobicContact CE1-CD2 4.06Å; F363-L367 HydrophobicContact CZ-CD2 4.38Å; F363-L367 WeakPolarHBondContact O-CB 3.13Å; F363-L367 PolarHBondContact O-N 3.32Å; S364-L367 PolarHBondContact O-N 3.34Å; G365-L367 VanDerWaalsContact C-N 3.31Å; G365-L367 PolarHBondContact O-N 2.98Å; L367-F370 PolarHBondContact O-N 3.38Å; L367-I371 HydrophobicContact CD1-CD1 4.16Å; L367-I371 HydrophobicContact CD1-CG1 4.38Å; L367-I371 HydrophobicContact CG-CD1 4.04Å; L367-I371 VanDerWaalsContact O-CG1 3.27Å; L367-I371 WeakPolarHBondContact O-CG1 3.29Å; L367-I371 PolarHBondContact O-N 2.93Å
368C95.3Very high92.4Very high12 Ų1244.7 Ų44.78%0.08125%0.248CC..Hα-helixtrans-61.3-45.8175.6-70.50000111.9S364 G365 I371 F372 F401 A405S364-C368 PolarHBondContact O-N 2.85Å; S364-C368 PolarHBondContact O-SG 2.92Å; G365-C368 PolarHBondContact O-N 3.29Å; C368-I371 PolarHBondContact O-N 3.17Å; C368-F372 WeakPolarHBondContact O-CB 3.4Å; C368-F372 PolarHBondContact O-N 3.29Å; C368-F401 HydrophobicContact CB-CD1 4.41Å; C368-A405 HydrophobicContact CB-CB 4.32Å
369L94.5Very high92.9Very high78 Ų7845.4 Ų45.441%0.40825%0.254SS..Hα-helixtrans-65.9-40.5176.9-67.8176.1000112.1G365 C366 I371 F372 D373 A405G365-L369 WeakPolarHBondContact O-CG 3.37Å; G365-L369 PolarHBondContact O-N 3.1Å; C366-L369 PolarHBondContact O-N 2.83Å; L369-I371 PolarHBondContact O-N 3.23Å; L369-F372 WeakPolarHBondContact O-CB 3.43Å; L369-F372 PolarHBondContact O-N 2.93Å; L369-D373 PolarHBondContact O-N 3.11Å; L369-A405 HydrophobicContact CD1-CB 4.4Å; L369-A405 HydrophobicContact CD2-CB 3.75Å; L369-A405 HydrophobicContact CG-CB 3.78Å
370F94.9Very high93Very high103 Ų10345.6 Ų45.645%0.45225%0.254SS..Hα-helixtrans-60.9-43.2175.6172-103.7000112.3L322 C366 L367 F372 A374L322-F370 HydrophobicContact CD1-CD2 3.7Å; L322-F370 HydrophobicContact CD1-CE2 3.7Å; C366-F370 WeakPolarHBondContact O-CB 3.18Å; C366-F370 PolarHBondContact O-N 3.21Å; L367-F370 PolarHBondContact O-N 3.38Å; F370-F372 VanDerWaalsContact C-N 3.33Å; F370-A374 VanDerWaalsContact O-CB 3.22Å; F370-A374 WeakPolarHBondContact O-CB 3.45Å; F370-A374 PolarHBondContact O-N 3.41Å
371I94.6Very high93Very high57 Ų5746.8 Ų46.829%0.29226%0.256SS..Hα-helixtrans-64.7-41.5176.3-67.3166000110.2L367 C368 L369 A374 C375 F401L367-I371 HydrophobicContact CD1-CD1 4.16Å; L367-I371 HydrophobicContact CD1-CG1 4.38Å; L367-I371 HydrophobicContact CG-CD1 4.04Å; L367-I371 VanDerWaalsContact O-CG1 3.27Å; L367-I371 WeakPolarHBondContact O-CG1 3.29Å; L367-I371 PolarHBondContact O-N 2.93Å; C368-I371 PolarHBondContact O-N 3.17Å; L369-I371 PolarHBondContact O-N 3.23Å; I371-A374 PolarHBondContact O-N 3.47Å; I371-C375 WeakPolarHBondContact O-CB 3.47Å; I371-C375 PolarHBondContact O-N 2.61Å; I371-C375 PolarHBondContact O-SG 3.49Å; I371-F401 HydrophobicContact CB-CE1 4.32Å; I371-F401 HydrophobicContact CB-CZ 4.41Å; I371-F401 HydrophobicContact CD1-CE1 4.36Å; I371-F401 HydrophobicContact CG2-CD1 4.4Å; I371-F401 HydrophobicContact CG2-CD2 4.34Å; I371-F401 HydrophobicContact CG2-CE1 3.81Å; I371-F401 HydrophobicContact CG2-CE2 3.73Å; I371-F401 HydrophobicContact CG2-CZ 3.45Å; I371-F401 VanDerWaalsContact CG2-CZ 3.45Å
372F93.8Very high93Very high21 Ų2151.7 Ų51.79%0.09229%0.285CS..Hα-helixtrans-58.8-53.4175.6172.2-102.3000111.8C368 L369 F370 A374 C375 E376 I388 W389 A398 F401 I402C368-F372 WeakPolarHBondContact O-CB 3.4Å; C368-F372 PolarHBondContact O-N 3.29Å; L369-F372 WeakPolarHBondContact O-CB 3.43Å; L369-F372 PolarHBondContact O-N 2.93Å; F370-F372 VanDerWaalsContact C-N 3.33Å; F372-A374 VanDerWaalsContact C-N 3.3Å; F372-A374 PolarHBondContact O-N 3.34Å; F372-C375 PolarHBondContact O-N 2.84Å; F372-C375 VanDerWaalsContact O-N 3.11Å; F372-E376 WeakPolarHBondContact CE1-OE2 3.41Å; F372-E376 WeakPolarHBondContact CZ-OE2 3.41Å; F372-E376 PolarHBondContact O-N 3.18Å; F372-I388 HydrophobicContact CE2-CG2 4.22Å; F372-W389 AromaticContact CE2-CZ2 3.99Å; F372-W389 HydrophobicContact CE2-CZ2 3.99Å; F372-W389 AromaticContact CZ-CZ2 3.97Å; F372-W389 HydrophobicContact CZ-CZ2 3.97Å; F372-A398 HydrophobicContact CD2-CB 4.14Å; F372-A398 HydrophobicContact CE2-CB 3.82Å; F372-F401 HydrophobicContact CB-CB 4.17Å; F372-I402 HydrophobicContact CD2-CG1 4.49Å; F372-I402 HydrophobicContact CE2-CD1 4.11Å; F372-I402 HydrophobicContact CZ-CD1 4.24Å
373D92.7Very high93Very high44 Ų4452.9 Ų52.924%0.23529%0.291CS..Hα-helixtrans-61.5-38178.9-67.1-19.9000111.9L318 L369 E376 R377 G378L318-D373 HydrophobicContact CD1-CB 4.4Å; L369-D373 PolarHBondContact O-N 3.11Å; D373-E376 PolarHBondContact O-N 2.88Å; D373-R377 WeakPolarHBondContact O-CB 3.33Å; D373-R377 PolarHBondContact O-N 3.47Å; D373-G378 PolarHBondContact O-N 3.3Å
374A92.5Very high93Very high39 Ų3947.4 Ų47.432%0.32227%0.269SS..Hα-helixtrans-67.8-35.1176.400000112.6F370 I371 F372 G378F370-A374 VanDerWaalsContact O-CB 3.22Å; F370-A374 WeakPolarHBondContact O-CB 3.45Å; F370-A374 PolarHBondContact O-N 3.41Å; I371-A374 PolarHBondContact O-N 3.47Å; F372-A374 VanDerWaalsContact C-N 3.3Å; F372-A374 PolarHBondContact O-N 3.34Å; A374-G378 WeakPolarHBondContact O-CA 3.04Å; A374-G378 PolarHBondContact O-N 2.97Å
375C92.4Very high93Very high50 Ų5044.7 Ų44.734%0.33825%0.25SC..Hα-helixtrans-75.9-31.4176.2-73.80000112.9I371 F372 V379 Y386 I388I371-C375 WeakPolarHBondContact O-CB 3.47Å; I371-C375 PolarHBondContact O-N 2.61Å; I371-C375 PolarHBondContact O-SG 3.49Å; F372-C375 PolarHBondContact O-N 2.84Å; F372-C375 VanDerWaalsContact O-N 3.11Å; C375-V379 WeakPolarHBondContact O-CG2 3.29Å; C375-Y386 WeakPolarHBondContact O-CE1 3.41Å; C375-I388 HydrophobicContact CB-CD1 4.11Å
376E90.6Very high92.9Very high25 Ų2547.7 Ų47.712%0.11726%0.26CS..Hα-helixtrans-86.3-78177.4-172.6171-129.400110.5F372 D373 G378 V379 H380 I388 W389F372-E376 WeakPolarHBondContact CE1-OE2 3.41Å; F372-E376 WeakPolarHBondContact CZ-OE2 3.41Å; F372-E376 PolarHBondContact O-N 3.18Å; D373-E376 PolarHBondContact O-N 2.88Å; E376-G378 VanDerWaalsContact C-N 3.34Å; E376-G378 PolarHBondContact O-N 3.15Å; E376-V379 PolarHBondContact O-N 3.32Å; E376-H380 PolarHBondContact O-CD2 3.08Å; E376-H380 PolarHBondContact O-N 3Å; E376-H380 PolarHBondContact O-NE2 3.28Å; E376-I388 HydrophobicContact CB-CG2 4.42Å; E376-I388 HydrophobicContact CG-CG2 4.32Å; E376-W389 PolarHBondContact OE1-NE1 3.24Å
377R90.4Very high92.7Very high66 Ų6646.1 Ų46.125%0.24925%0.249CC..Hα-helixtrans-69.4-27.6-175.8-64.5-178.2178-169.71.2113.6L318 D321 D373 V379 H380L318-R377 HydrophobicContact CB-CB 4.49Å; L318-R377 HydrophobicContact CD1-CB 4.21Å; D321-R377 IonicContact OD1-NH1 3.5Å; D321-R377 PolarHBondContact OD1-NH1 3.09Å; D321-R377 WeakPolarHBondContact OD2-CD 3.3Å; D321-R377 IonicContact OD2-CZ 3.82Å; D321-R377 IonicContact OD2-NE 2.75Å; D321-R377 IonicContact OD2-NH1 3.55Å; D321-R377 PolarHBondContact OD2-NH1 3.27Å; D373-R377 WeakPolarHBondContact O-CB 3.33Å; D373-R377 PolarHBondContact O-N 3.47Å; R377-V379 VanDerWaalsContact C-N 3.3Å; R377-V379 PolarHBondContact O-N 3.02Å; R377-H380 WeakPolarHBondContact O-CB 3.48Å; R377-H380 PolarHBondContact O-N 3.15Å
378G92.4Very high92.5Very high19 Ų1942.8 Ų42.820%0.19623%0.231CC..Hα-helixtrans-66.2-32.5174.200000113D373 A374 E376 L381D373-G378 PolarHBondContact O-N 3.3Å; A374-G378 WeakPolarHBondContact O-CA 3.04Å; A374-G378 PolarHBondContact O-N 2.97Å; E376-G378 VanDerWaalsContact C-N 3.34Å; E376-G378 PolarHBondContact O-N 3.15Å; G378-L381 WeakPolarHBondContact O-CB 3.22Å
379V91.9Very high92.2Very high44 Ų4446.2 Ų46.227%0.26724%0.243SC..Hα-helixtrans-77.5-29.7176.2-179.20000111.3C375 E376 R377 L381 T382 N383 Y386C375-V379 WeakPolarHBondContact O-CG2 3.29Å; E376-V379 PolarHBondContact O-N 3.32Å; R377-V379 VanDerWaalsContact C-N 3.3Å; R377-V379 PolarHBondContact O-N 3.02Å; V379-L381 PolarHBondContact O-N 3.49Å; V379-T382 PolarHBondContact O-N 3.42Å; V379-T382 PolarHBondContact O-OG1 2.51Å; V379-N383 PolarHBondContact O-N 2.91Å; V379-Y386 HydrophobicContact CB-CD1 3.59Å; V379-Y386 HydrophobicContact CB-CE1 3.91Å; V379-Y386 HydrophobicContact CB-CG 4.07Å; V379-Y386 HydrophobicContact CG1-CD1 3.5Å; V379-Y386 VanDerWaalsContact CG1-CD1 3.5Å; V379-Y386 HydrophobicContact CG1-CD2 3.88Å; V379-Y386 HydrophobicContact CG1-CE1 4Å; V379-Y386 HydrophobicContact CG1-CE2 4.34Å; V379-Y386 HydrophobicContact CG1-CG 3.42Å; V379-Y386 VanDerWaalsContact CG1-CG 3.42Å; V379-Y386 HydrophobicContact CG2-CD1 4.34Å; V379-Y386 HydrophobicContact CG2-CE1 4.16Å
380H90.9Very high91.7Very high26 Ų2643.6 Ų43.612%0.1223%0.231CC..Hα-helixtrans-55.4-26.6175.3-63.1178000113E205 E376 R377 T382 N383 Y386E205-H380 IonicContact OE2-CE1 2.61Å; E205-H380 PolarHBondContact OE2-CE1 2.96Å; E205-H380 IonicContact OE2-ND1 2.84Å; E205-H380 PolarHBondContact OE2-ND1 3.38Å; E376-H380 PolarHBondContact O-CD2 3.08Å; E376-H380 PolarHBondContact O-N 3Å; E376-H380 PolarHBondContact O-NE2 3.28Å; R377-H380 WeakPolarHBondContact O-CB 3.48Å; R377-H380 PolarHBondContact O-N 3.15Å; H380-T382 PolarHBondContact O-N 2.95Å; H380-N383 WeakPolarHBondContact CA-O 3.46Å; H380-N383 CarbonylContact O-C 3.55Å; H380-Y386 PolarHBondContact CD2-O 3.24Å; H380-Y386 PolarHBondContact NE2-O 2.99Å
381L89.8Confident91.3Very high74 Ų7441.9 Ų41.939%0.38723%0.229SC..THydrogen-bonded Turntrans-59-31174.5-64.2177.2000114P314 F315 L318 G378 V379P314-L381 HydrophobicContact CB-CD2 4.17Å; P314-L381 HydrophobicContact CG-CD2 4.41Å; P314-L381 WeakPolarHBondContact O-CD2 3.45Å; F315-L381 HydrophobicContact CB-CD1 4.41Å; F315-L381 HydrophobicContact CB-CD2 3.74Å; L318-L381 HydrophobicContact CD2-CD1 4.44Å; G378-L381 WeakPolarHBondContact O-CB 3.22Å; V379-L381 PolarHBondContact O-N 3.49Å
382T91Very high90.9Very high113 Ų11344.8 Ų44.869%0.69325%0.245SC*.THydrogen-bonded Turntrans-103.2-36.4-179.759.90000111.8V379 H380V379-T382 PolarHBondContact O-N 3.42Å; V379-T382 PolarHBondContact O-OG1 2.51Å; H380-T382 PolarHBondContact O-N 2.95Å
383N92.6Very high90.7Very high34 Ų3448.9 Ų48.918%0.18227%0.271CS..  trans-139.299.7179.1-177.42.4000109.9I173 V379 H380 F385 Y386I173-N383 HydrophobicContact CD1-CB 4.3Å; V379-N383 PolarHBondContact O-N 2.91Å; H380-N383 WeakPolarHBondContact CA-O 3.46Å; H380-N383 CarbonylContact O-C 3.55Å; N383-F385 PolarHBondContact O-N 2.84Å; N383-F385 VanDerWaalsContact O-N 3.14Å; N383-F385 WeakPolarHBondContact OD1-CB 3.28Å; N383-F385 PolarHBondContact OD1-N 3.36Å; N383-Y386 VanDerWaalsContact O-CB 3.3Å; N383-Y386 WeakPolarHBondContact O-CB 3.47Å; N383-Y386 PolarHBondContact O-N 2.89Å
384P93.8Very high90.5Very high14 Ų1447.1 Ų47.19%0.09126%0.264CS..THydrogen-bonded Turntrans-66.3-14.2179.927.9-36.6000113.5I173 F204 E205 L206I173-P384 HydrophobicContact CG2-CG 4.12Å; F204-P384 CarbonylContact C-O 3.51Å; F204-P384 WeakPolarHBondContact CA-O 3.31Å; E205-P384 PolarHBondContact N-O 2.97Å; E205-P384 WeakPolarHBondContact O-CB 3.45Å; L206-P384 HydrophobicContact CD2-CB 3.61Å; L206-P384 HydrophobicContact CD2-CG 3.87Å
385F94Very high90.4Very high0 Ų046.1 Ų46.10%025%0.254CS..THydrogen-bonded Turntrans-911.6175.3-63.1-90.5000113.3V155 M157 I173 T175 I177 R179 L203 F204 L216 N383V155-F385 HydrophobicContact CB-CD1 4.27Å; V155-F385 HydrophobicContact CB-CE1 3.93Å; V155-F385 HydrophobicContact CB-CZ 4.23Å; V155-F385 HydrophobicContact CG1-CE1 4.45Å; V155-F385 HydrophobicContact CG2-CB 4.47Å; V155-F385 HydrophobicContact CG2-CD1 3.63Å; V155-F385 HydrophobicContact CG2-CD2 4.11Å; V155-F385 HydrophobicContact CG2-CE1 3.74Å; V155-F385 HydrophobicContact CG2-CE2 4.22Å; V155-F385 HydrophobicContact CG2-CG 3.83Å; V155-F385 HydrophobicContact CG2-CZ 4.03Å; M157-F385 HydrophobicContact CB-CE2 4.08Å; M157-F385 HydrophobicContact CB-CZ 3.97Å; M157-F385 HydrophobicContact CE-CZ 3.96Å; I173-F385 HydrophobicContact CG2-CD2 3.92Å; I173-F385 HydrophobicContact CG2-CE2 3.5Å; I173-F385 VanDerWaalsContact CG2-CE2 3.5Å; T175-F385 HydrophobicContact CG2-CB 4.06Å; T175-F385 HydrophobicContact CG2-CD2 3.95Å; T175-F385 HydrophobicContact CG2-CG 4.18Å; I177-F385 HydrophobicContact CD1-CD1 4.39Å; I177-F385 HydrophobicContact CG2-CB 3.78Å; R179-F385 PolarHBondContact NH2-O 2.94Å; L203-F385 HydrophobicContact CD1-CD1 4.19Å; L203-F385 HydrophobicContact CD1-CE1 4.32Å; L203-F385 HydrophobicContact CD2-CE1 4.45Å; L203-F385 HydrophobicContact CG-CD1 4.08Å; L203-F385 HydrophobicContact CG-CE1 3.97Å; L203-F385 WeakPolarHBondContact O-CA 3.46Å; L203-F385 WeakPolarHBondContact O-CD1 3.31Å; F204-F385 HydrophobicContact CB-CD1 3.74Å; F204-F385 HydrophobicContact CB-CE1 3.76Å; F204-F385 HydrophobicContact CB-CG 4.19Å; F204-F385 HydrophobicContact CB-CZ 4.21Å; F204-F385 HydrophobicContact CD1-CE1 4.07Å; F204-F385 HydrophobicContact CG-CE1 4.3Å; L216-F385 HydrophobicContact CD1-CE1 4.09Å; L216-F385 HydrophobicContact CD1-CZ 3.91Å; N383-F385 PolarHBondContact O-N 2.84Å; N383-F385 VanDerWaalsContact O-N 3.14Å; N383-F385 WeakPolarHBondContact OD1-CB 3.28Å; N383-F385 PolarHBondContact OD1-N 3.36Å
386Y92.3Very high90.5Very high69 Ų6949 Ų4927%0.27127%0.265SS..  trans-68.3147.3173.1-179.9-98.5000110.1C375 V379 H380 N383 I388C375-Y386 WeakPolarHBondContact O-CE1 3.41Å; V379-Y386 HydrophobicContact CB-CD1 3.59Å; V379-Y386 HydrophobicContact CB-CE1 3.91Å; V379-Y386 HydrophobicContact CB-CG 4.07Å; V379-Y386 HydrophobicContact CG1-CD1 3.5Å; V379-Y386 VanDerWaalsContact CG1-CD1 3.5Å; V379-Y386 HydrophobicContact CG1-CD2 3.88Å; V379-Y386 HydrophobicContact CG1-CE1 4Å; V379-Y386 HydrophobicContact CG1-CE2 4.34Å; V379-Y386 HydrophobicContact CG1-CG 3.42Å; V379-Y386 VanDerWaalsContact CG1-CG 3.42Å; V379-Y386 HydrophobicContact CG2-CD1 4.34Å; V379-Y386 HydrophobicContact CG2-CE1 4.16Å; H380-Y386 PolarHBondContact CD2-O 3.24Å; H380-Y386 PolarHBondContact NE2-O 2.99Å; N383-Y386 VanDerWaalsContact O-CB 3.3Å; N383-Y386 WeakPolarHBondContact O-CB 3.47Å; N383-Y386 PolarHBondContact O-N 2.89Å; Y386-I388 HydrophobicContact CE1-CB 4.32Å
387S91.9Very high90.6Very high6 Ų651.5 Ų51.54%0.04228%0.279CS..  trans-150.5129.6168.3171.40000107.5W389 S390S387-W389 PolarHBondContact O-N 2.89Å; S387-W389 PolarHBondContact OG-N 2.96Å; S387-S390 WeakPolarHBondContact O-CB 3.41Å; S387-S390 PolarHBondContact O-N 3.26Å; S387-S390 VanDerWaalsContact O-N 3.15Å; S387-S390 PolarHBondContact O-OG 3.49Å
388I90.2Very high90.7Very high5 Ų548.3 Ų48.33%0.02627%0.267CS..G310 helixtrans-62.6-27.3-179.5-167.8164.3000111.7F372 C375 E376 Y386 S390 G394 T395 A398F372-I388 HydrophobicContact CE2-CG2 4.22Å; C375-I388 HydrophobicContact CB-CD1 4.11Å; E376-I388 HydrophobicContact CB-CG2 4.42Å; E376-I388 HydrophobicContact CG-CG2 4.32Å; Y386-I388 HydrophobicContact CE1-CB 4.32Å; I388-S390 PolarHBondContact O-N 3.42Å; I388-G394 WeakPolarHBondContact CG1-O 3.39Å; I388-G394 CarbonylContact O-C 3.57Å; I388-G394 VanDerWaalsContact O-C 3.3Å; I388-G394 WeakPolarHBondContact O-CA 3.42Å; I388-T395 PolarHBondContact O-N 3.11Å; I388-A398 HydrophobicContact CD1-CB 3.93Å; I388-A398 HydrophobicContact CG1-CB 4.14Å; I388-A398 HydrophobicContact CG2-CB 4.16Å
389W88.1Confident90.8Very high84 Ų8452.8 Ų52.832%0.31828%0.279SS..G310 helixtrans-73.3-8179.5-51.3106.8000114.1F372 E376 S387 T395 A398 Y399 I402F372-W389 AromaticContact CE2-CZ2 3.99Å; F372-W389 HydrophobicContact CE2-CZ2 3.99Å; F372-W389 AromaticContact CZ-CZ2 3.97Å; F372-W389 HydrophobicContact CZ-CZ2 3.97Å; E376-W389 PolarHBondContact OE1-NE1 3.24Å; S387-W389 PolarHBondContact O-N 2.89Å; S387-W389 PolarHBondContact OG-N 2.96Å; W389-T395 WeakPolarHBondContact CA-OG1 3.33Å; W389-T395 HydrophobicContact CE3-CG2 4.03Å; W389-T395 HydrophobicContact CZ3-CG2 4.32Å; W389-T395 PolarHBondContact O-OG1 3.04Å; W389-A398 HydrophobicContact CE3-CB 4.36Å; W389-A398 HydrophobicContact CH2-CB 3.76Å; W389-A398 HydrophobicContact CZ2-CB 4.17Å; W389-A398 HydrophobicContact CZ3-CB 3.85Å; W389-Y399 HydrophobicContact CH2-CE1 4.42Å; W389-Y399 HydrophobicContact CZ3-CD1 4.26Å; W389-Y399 AromaticContact CZ3-CE1 3.92Å; W389-Y399 HydrophobicContact CZ3-CE1 3.92Å; W389-Y399 HydrophobicContact CZ3-CE2 4.42Å; W389-I402 HydrophobicContact CH2-CD1 3.71Å; W389-I402 HydrophobicContact CZ2-CD1 4.12Å
390S85.2Confident90.9Very high22 Ų2254.9 Ų54.915%0.15429%0.288CS..G310 helixtrans-77.1-31.5-178.962.90000113.9S178 S387 I388S178-S390 WeakPolarHBondContact O-CB 3.01Å; S387-S390 WeakPolarHBondContact O-CB 3.41Å; S387-S390 PolarHBondContact O-N 3.26Å; S387-S390 VanDerWaalsContact O-N 3.15Å; S387-S390 PolarHBondContact O-OG 3.49Å; I388-S390 PolarHBondContact O-N 3.42Å
391T85.7Confident91.1Very high67 Ų6755.5 Ų55.541%0.41129%0.291SS..SBendtrans-106.3145.1-177.464.40000110.8V393 G394 T395T391-V393 VanDerWaalsContact C-N 3.28Å; T391-V393 PolarHBondContact O-N 2.82Å; T391-G394 PolarHBondContact O-N 3.24Å; T391-G394 WeakPolarHBondContact OG1-CA 3.31Å; T391-G394 PolarHBondContact OG1-N 3.37Å; T391-T395 VanDerWaalsContact O-CB 3.3Å; T391-T395 WeakPolarHBondContact O-CB 3.25Å; T391-T395 PolarHBondContact O-N 3.3Å; T391-T395 PolarHBondContact O-OG1 3.1Å
392N85.8Confident91.3Very high118 Ų11854.6 Ų54.663%0.63129%0.286SS*.Hα-helixtrans-60.8-39.4176.4-69.8-32.4000111.8N396N392-N396 WeakPolarHBondContact O-CB 3.35Å; N392-N396 PolarHBondContact O-N 3.23Å; N392-N396 PolarHBondContact O-ND2 3.34Å
393V89.7Confident91.5Very high107 Ų10753.7 Ų53.765%0.64828%0.276SS*.Hα-helixtrans-67.5-47.1177.4-178.90000110.7T391 N396 L397T391-V393 VanDerWaalsContact C-N 3.28Å; T391-V393 PolarHBondContact O-N 2.82Å; V393-N396 PolarHBondContact O-N 2.95Å; V393-L397 HydrophobicContact CG1-CD1 4.11Å; V393-L397 WeakPolarHBondContact O-CG 3.5Å; V393-L397 PolarHBondContact O-N 3.48Å
394G89.8Confident91.7Very high7 Ų755.5 Ų55.57%0.07229%0.285CS..Hα-helixtrans-60.2-47176.900000112.2I388 T391 N396 L397 A398I388-G394 WeakPolarHBondContact CG1-O 3.39Å; I388-G394 CarbonylContact O-C 3.57Å; I388-G394 VanDerWaalsContact O-C 3.3Å; I388-G394 WeakPolarHBondContact O-CA 3.42Å; T391-G394 PolarHBondContact O-N 3.24Å; T391-G394 WeakPolarHBondContact OG1-CA 3.31Å; T391-G394 PolarHBondContact OG1-N 3.37Å; G394-N396 PolarHBondContact O-N 3.45Å; G394-L397 WeakPolarHBondContact O-CB 2.93Å; G394-L397 PolarHBondContact O-N 3.49Å; G394-L397 VanDerWaalsContact O-N 3.16Å; G394-A398 WeakPolarHBondContact O-CB 3.48Å; G394-A398 PolarHBondContact O-N 3.12Å
395T90.2Very high91.7Very high19 Ų1955.2 Ų55.212%0.11728%0.284CS..Hα-helixtrans-60.1-44.6177.6-59.70000111.9I388 W389 T391 L397 A398 Y399I388-T395 PolarHBondContact O-N 3.11Å; W389-T395 WeakPolarHBondContact CA-OG1 3.33Å; W389-T395 HydrophobicContact CE3-CG2 4.03Å; W389-T395 HydrophobicContact CZ3-CG2 4.32Å; W389-T395 PolarHBondContact O-OG1 3.04Å; T391-T395 VanDerWaalsContact O-CB 3.3Å; T391-T395 WeakPolarHBondContact O-CB 3.25Å; T391-T395 PolarHBondContact O-N 3.3Å; T391-T395 PolarHBondContact O-OG1 3.1Å; T395-L397 VanDerWaalsContact C-N 3.34Å; T395-L397 PolarHBondContact O-N 3.31Å; T395-A398 PolarHBondContact O-N 3.28Å; T395-Y399 HydrophobicContact CG2-CD2 3.64Å; T395-Y399 HydrophobicContact CG2-CE2 3.28Å; T395-Y399 WeakPolarHBondContact O-CD2 3.45Å; T395-Y399 PolarHBondContact O-N 3.08Å
396N93.8Very high91.8Very high109 Ų10959.7 Ų59.758%0.58331%0.311SS*.Hα-helixtrans-64.2-38.3176.5-73-17.6000112.2N392 V393 G394 L400N392-N396 WeakPolarHBondContact O-CB 3.35Å; N392-N396 PolarHBondContact O-N 3.23Å; N392-N396 PolarHBondContact O-ND2 3.34Å; V393-N396 PolarHBondContact O-N 2.95Å; G394-N396 PolarHBondContact O-N 3.45Å; N396-L400 WeakPolarHBondContact O-CB 3.04Å; N396-L400 PolarHBondContact O-N 2.92Å
397L93.2Very high91.9Very high78 Ų7860.9 Ų60.941%0.40832%0.321SS..Hα-helixtrans-67.4-43.2174.6-73.8172000111.9V393 G394 T395 L400 F401V393-L397 HydrophobicContact CG1-CD1 4.11Å; V393-L397 WeakPolarHBondContact O-CG 3.5Å; V393-L397 PolarHBondContact O-N 3.48Å; G394-L397 WeakPolarHBondContact O-CB 2.93Å; G394-L397 PolarHBondContact O-N 3.49Å; G394-L397 VanDerWaalsContact O-N 3.16Å; T395-L397 VanDerWaalsContact C-N 3.34Å; T395-L397 PolarHBondContact O-N 3.31Å; L397-L400 WeakPolarHBondContact O-CB 3.37Å; L397-L400 PolarHBondContact O-N 3.35Å; L397-F401 HydrophobicContact CB-CE2 4.37Å; L397-F401 WeakPolarHBondContact O-CD2 2.88Å; L397-F401 PolarHBondContact O-N 3.3Å
398A92.8Very high92.1Very high0 Ų061.3 Ų61.30%032%0.324CS..Hα-helixtrans-58-50.9174.800000110.9F372 I388 W389 G394 T395 L400 F401 I402F372-A398 HydrophobicContact CD2-CB 4.14Å; F372-A398 HydrophobicContact CE2-CB 3.82Å; I388-A398 HydrophobicContact CD1-CB 3.93Å; I388-A398 HydrophobicContact CG1-CB 4.14Å; I388-A398 HydrophobicContact CG2-CB 4.16Å; W389-A398 HydrophobicContact CE3-CB 4.36Å; W389-A398 HydrophobicContact CH2-CB 3.76Å; W389-A398 HydrophobicContact CZ2-CB 4.17Å; W389-A398 HydrophobicContact CZ3-CB 3.85Å; G394-A398 WeakPolarHBondContact O-CB 3.48Å; G394-A398 PolarHBondContact O-N 3.12Å; T395-A398 PolarHBondContact O-N 3.28Å; A398-L400 VanDerWaalsContact C-N 3.3Å; A398-L400 PolarHBondContact O-N 2.93Å; A398-F401 PolarHBondContact O-N 2.65Å; A398-I402 VanDerWaalsContact O-CG1 3.31Å; A398-I402 WeakPolarHBondContact O-CG1 3.47Å; A398-I402 PolarHBondContact O-N 3.15Å
399Y93.9Very high92.2Very high113 Ų11363.1 Ų63.144%0.44334%0.34SS..Hα-helixtrans-58.1-41.9175-76-48.4000112.2W389 T395 I402 I403W389-Y399 HydrophobicContact CH2-CE1 4.42Å; W389-Y399 HydrophobicContact CZ3-CD1 4.26Å; W389-Y399 AromaticContact CZ3-CE1 3.92Å; W389-Y399 HydrophobicContact CZ3-CE1 3.92Å; W389-Y399 HydrophobicContact CZ3-CE2 4.42Å; T395-Y399 HydrophobicContact CG2-CD2 3.64Å; T395-Y399 HydrophobicContact CG2-CE2 3.28Å; T395-Y399 WeakPolarHBondContact O-CD2 3.45Å; T395-Y399 PolarHBondContact O-N 3.08Å; Y399-I402 PolarHBondContact O-N 3.18Å; Y399-I403 VanDerWaalsContact O-CB 3.24Å; Y399-I403 WeakPolarHBondContact O-CB 3.49Å; Y399-I403 WeakPolarHBondContact O-CD1 3.37Å; Y399-I403 WeakPolarHBondContact O-CG1 3.36Å; Y399-I403 PolarHBondContact O-N 3.46Å
400L95.2Very high92.5Very high88 Ų8861.7 Ų61.746%0.46135%0.346SS..Hα-helixtrans-58.1-50.2176.6178.365.8000111.5N396 L397 A398 I403 L404N396-L400 WeakPolarHBondContact O-CB 3.04Å; N396-L400 PolarHBondContact O-N 2.92Å; L397-L400 WeakPolarHBondContact O-CB 3.37Å; L397-L400 PolarHBondContact O-N 3.35Å; A398-L400 VanDerWaalsContact C-N 3.3Å; A398-L400 PolarHBondContact O-N 2.93Å; L400-I403 PolarHBondContact O-N 2.79Å; L400-L404 HydrophobicContact CD1-CD1 4.05Å; L400-L404 HydrophobicContact CD1-CG 4.27Å; L400-L404 HydrophobicContact CG-CD1 4.05Å; L400-L404 WeakPolarHBondContact O-CB 3.2Å; L400-L404 VanDerWaalsContact O-CG 3.22Å; L400-L404 WeakPolarHBondContact O-CG 3.2Å; L400-L404 PolarHBondContact O-N 3.34Å
401F94.7Very high92.9Very high38 Ų3863.4 Ų63.417%0.16736%0.355CS..Hα-helixtrans-64.4-42.4-179.9-68-55.7000112.5C368 I371 F372 L397 A398 L404 A405C368-F401 HydrophobicContact CB-CD1 4.41Å; I371-F401 HydrophobicContact CB-CE1 4.32Å; I371-F401 HydrophobicContact CB-CZ 4.41Å; I371-F401 HydrophobicContact CD1-CE1 4.36Å; I371-F401 HydrophobicContact CG2-CD1 4.4Å; I371-F401 HydrophobicContact CG2-CD2 4.34Å; I371-F401 HydrophobicContact CG2-CE1 3.81Å; I371-F401 HydrophobicContact CG2-CE2 3.73Å; I371-F401 HydrophobicContact CG2-CZ 3.45Å; I371-F401 VanDerWaalsContact CG2-CZ 3.45Å; F372-F401 HydrophobicContact CB-CB 4.17Å; L397-F401 HydrophobicContact CB-CE2 4.37Å; L397-F401 WeakPolarHBondContact O-CD2 2.88Å; L397-F401 PolarHBondContact O-N 3.3Å; A398-F401 PolarHBondContact O-N 2.65Å; F401-L404 PolarHBondContact O-N 3.45Å; F401-A405 WeakPolarHBondContact O-CB 3.35Å; F401-A405 PolarHBondContact O-N 2.94Å
402I93.7Very high93.2Very high55 Ų5560.6 Ų60.628%0.28234%0.337SS..Hα-helixtrans-65-46.1177.9-66.2166.3000110.7F372 W389 A398 Y399 L404 A405 V406F372-I402 HydrophobicContact CD2-CG1 4.49Å; F372-I402 HydrophobicContact CE2-CD1 4.11Å; F372-I402 HydrophobicContact CZ-CD1 4.24Å; W389-I402 HydrophobicContact CH2-CD1 3.71Å; W389-I402 HydrophobicContact CZ2-CD1 4.12Å; A398-I402 VanDerWaalsContact O-CG1 3.31Å; A398-I402 WeakPolarHBondContact O-CG1 3.47Å; A398-I402 PolarHBondContact O-N 3.15Å; Y399-I402 PolarHBondContact O-N 3.18Å; I402-L404 PolarHBondContact O-N 3.18Å; I402-A405 WeakPolarHBondContact O-CB 3.3Å; I402-A405 PolarHBondContact O-N 3.41Å; I402-V406 HydrophobicContact CG2-CG2 4.43Å; I402-V406 WeakPolarHBondContact O-CG2 3.42Å; I402-V406 PolarHBondContact O-N 3.49Å
403I95.6Very high93.5Very high94 Ų9461 Ų6148%0.48233%0.334SS..Hα-helixtrans-62-44.2178.6-70.6166.4000110.5Y399 L400 A405 V406 I407Y399-I403 VanDerWaalsContact O-CB 3.24Å; Y399-I403 WeakPolarHBondContact O-CB 3.49Å; Y399-I403 WeakPolarHBondContact O-CD1 3.37Å; Y399-I403 WeakPolarHBondContact O-CG1 3.36Å; Y399-I403 PolarHBondContact O-N 3.46Å; L400-I403 PolarHBondContact O-N 2.79Å; I403-A405 VanDerWaalsContact C-N 3.34Å; I403-A405 PolarHBondContact O-N 3.16Å; I403-V406 PolarHBondContact O-N 2.93Å; I403-I407 HydrophobicContact CG2-CD1 3.8Å; I403-I407 HydrophobicContact CG2-CG1 4.41Å; I403-I407 VanDerWaalsContact O-CG1 3.29Å; I403-I407 WeakPolarHBondContact O-CG1 3.35Å; I403-I407 PolarHBondContact O-N 3.38Å
404L95.7Very high93.6Very high72 Ų7260.5 Ų60.538%0.37733%0.331SS..Hα-helixtrans-61.7-41.4175.8-72.1173.3000111.9L400 F401 I402 I407 S408L400-L404 HydrophobicContact CD1-CD1 4.05Å; L400-L404 HydrophobicContact CD1-CG 4.27Å; L400-L404 HydrophobicContact CG-CD1 4.05Å; L400-L404 WeakPolarHBondContact O-CB 3.2Å; L400-L404 VanDerWaalsContact O-CG 3.22Å; L400-L404 WeakPolarHBondContact O-CG 3.2Å; L400-L404 PolarHBondContact O-N 3.34Å; F401-L404 PolarHBondContact O-N 3.45Å; I402-L404 PolarHBondContact O-N 3.18Å; L404-I407 PolarHBondContact O-N 3.36Å; L404-S408 WeakPolarHBondContact O-CB 3.5Å; L404-S408 PolarHBondContact O-N 3.48Å; L404-S408 PolarHBondContact O-OG 3.35Å
405A94.4Very high93.6Very high9 Ų963.6 Ų63.67%0.07434%0.342CS..Hα-helixtrans-62.5-44.4174.800000111.7C368 L369 F401 I402 I403 S408 A409C368-A405 HydrophobicContact CB-CB 4.32Å; L369-A405 HydrophobicContact CD1-CB 4.4Å; L369-A405 HydrophobicContact CD2-CB 3.75Å; L369-A405 HydrophobicContact CG-CB 3.78Å; F401-A405 WeakPolarHBondContact O-CB 3.35Å; F401-A405 PolarHBondContact O-N 2.94Å; I402-A405 WeakPolarHBondContact O-CB 3.3Å; I402-A405 PolarHBondContact O-N 3.41Å; I403-A405 VanDerWaalsContact C-N 3.34Å; I403-A405 PolarHBondContact O-N 3.16Å; A405-S408 PolarHBondContact O-N 3.09Å; A405-S408 PolarHBondContact O-OG 2.81Å; A405-A409 WeakPolarHBondContact O-CB 3.42Å; A405-A409 PolarHBondContact O-N 3.23Å
406V95.4Very high93.6Very high93 Ų9363.8 Ų63.856%0.56434%0.342SS*.Hα-helixtrans-62.5-44.5176.4171.80000111.7I402 I403 S408 A409 A410I402-V406 HydrophobicContact CG2-CG2 4.43Å; I402-V406 WeakPolarHBondContact O-CG2 3.42Å; I402-V406 PolarHBondContact O-N 3.49Å; I403-V406 PolarHBondContact O-N 2.93Å; V406-S408 VanDerWaalsContact C-N 3.32Å; V406-S408 PolarHBondContact O-N 3.05Å; V406-A409 PolarHBondContact O-N 2.92Å; V406-A410 PolarHBondContact O-N 3.26Å
407I95.8Very high93.5Very high94 Ų9461.8 Ų61.848%0.48234%0.336SS..Hα-helixtrans-60.1-45175.5-69.2167.4000110.1I403 L404 A409 A410 V411I403-I407 HydrophobicContact CG2-CD1 3.8Å; I403-I407 HydrophobicContact CG2-CG1 4.41Å; I403-I407 VanDerWaalsContact O-CG1 3.29Å; I403-I407 WeakPolarHBondContact O-CG1 3.35Å; I403-I407 PolarHBondContact O-N 3.38Å; L404-I407 PolarHBondContact O-N 3.36Å; I407-A409 VanDerWaalsContact C-N 3.32Å; I407-A409 PolarHBondContact O-N 2.76Å; I407-A410 PolarHBondContact O-N 2.69Å; I407-V411 HydrophobicContact CG2-CG2 4.48Å; I407-V411 WeakPolarHBondContact O-CG2 3.38Å; I407-V411 PolarHBondContact O-N 3.14Å
408S94.6Very high93.3Very high16 Ų1663.6 Ų63.611%0.11234%0.341CS..Hα-helixtrans-63-37.8178.778.10000112.5A361 G365 L404 A405 V406 V411 Y412A361-S408 WeakPolarHBondContact O-CB 3.33Å; G365-S408 WeakPolarHBondContact CA-OG 3.4Å; L404-S408 WeakPolarHBondContact O-CB 3.5Å; L404-S408 PolarHBondContact O-N 3.48Å; L404-S408 PolarHBondContact O-OG 3.35Å; A405-S408 PolarHBondContact O-N 3.09Å; A405-S408 PolarHBondContact O-OG 2.81Å; V406-S408 VanDerWaalsContact C-N 3.32Å; V406-S408 PolarHBondContact O-N 3.05Å; S408-V411 PolarHBondContact O-N 3.35Å; S408-Y412 WeakPolarHBondContact O-CB 3.37Å; S408-Y412 PolarHBondContact O-N 3.14Å
409A92.7Very high93.1Very high42 Ų4264.2 Ų64.235%0.34734%0.344SS..Hα-helixtrans-66.5-42.1174.800000111.4A405 V406 I407 Y412 F413A405-A409 WeakPolarHBondContact O-CB 3.42Å; A405-A409 PolarHBondContact O-N 3.23Å; V406-A409 PolarHBondContact O-N 2.92Å; I407-A409 VanDerWaalsContact C-N 3.32Å; I407-A409 PolarHBondContact O-N 2.76Å; A409-Y412 WeakPolarHBondContact O-CB 3.33Å; A409-Y412 PolarHBondContact O-N 3.33Å; A409-F413 WeakPolarHBondContact O-CD2 3.5Å; A409-F413 PolarHBondContact O-N 2.96Å
410A94.3Very high92.8Very high54 Ų5461.4 Ų61.445%0.44634%0.337SS..Hα-helixtrans-61.7-45.7175.200000111.7V406 I407 Y412 F413 V414V406-A410 PolarHBondContact O-N 3.26Å; I407-A410 PolarHBondContact O-N 2.69Å; A410-Y412 VanDerWaalsContact C-N 3.33Å; A410-Y412 PolarHBondContact O-N 3.42Å; A410-F413 PolarHBondContact O-N 2.92Å; A410-V414 WeakPolarHBondContact O-CG2 3.35Å; A410-V414 PolarHBondContact O-N 3.35Å
411V93.6Very high92.5Very high59 Ų5963.1 Ų63.136%0.35835%0.346SS..Hα-helixtrans-60.5-43.1174.7170.70000111.1A361 I407 S408 F413 V414 F415A361-V411 HydrophobicContact CB-CG1 4.13Å; I407-V411 HydrophobicContact CG2-CG2 4.48Å; I407-V411 WeakPolarHBondContact O-CG2 3.38Å; I407-V411 PolarHBondContact O-N 3.14Å; S408-V411 PolarHBondContact O-N 3.35Å; V411-F413 PolarHBondContact O-N 2.78Å; V411-V414 PolarHBondContact O-N 2.03Å; V411-F415 HydrophobicContact CG1-CD2 3.68Å; V411-F415 HydrophobicContact CG1-CE2 3.25Å; V411-F415 HydrophobicContact CG1-CZ 3.92Å; V411-F415 WeakPolarHBondContact O-CD2 3.18Å; V411-F415 WeakPolarHBondContact O-CG 3.34Å; V411-F415 PolarHBondContact O-N 2.89Å
412Y93.5Very high92.2Very high8 Ų866.3 Ų66.33%0.03136%0.357CS..Hα-helixtrans-56.5-48.5173.7169.4-90.4000112L332 L336 V362 S408 A409 A410 V414 F415 L416L332-Y412 WeakPolarHBondContact CA-OH 3.04Å; L332-Y412 HydrophobicContact CB-CE2 3.87Å; L332-Y412 HydrophobicContact CD2-CE1 3.72Å; L332-Y412 HydrophobicContact CD2-CE2 4.39Å; L332-Y412 WeakPolarHBondContact CD2-OH 3.49Å; L332-Y412 PolarHBondContact O-OH 3.12Å; L332-Y412 VanDerWaalsContact O-OH 3.05Å; L336-Y412 HydrophobicContact CD1-CD2 3.68Å; L336-Y412 HydrophobicContact CD1-CE2 3.42Å; L336-Y412 VanDerWaalsContact CD1-CE2 3.42Å; L336-Y412 HydrophobicContact CD2-CD2 4.4Å; L336-Y412 HydrophobicContact CD2-CE2 4.04Å; L336-Y412 HydrophobicContact CG-CD2 4.16Å; L336-Y412 HydrophobicContact CG-CE2 3.52Å; V362-Y412 HydrophobicContact CG2-CD2 3.44Å; V362-Y412 VanDerWaalsContact CG2-CD2 3.44Å; V362-Y412 HydrophobicContact CG2-CE2 3.69Å; S408-Y412 WeakPolarHBondContact O-CB 3.37Å; S408-Y412 PolarHBondContact O-N 3.14Å; A409-Y412 WeakPolarHBondContact O-CB 3.33Å; A409-Y412 PolarHBondContact O-N 3.33Å; A410-Y412 VanDerWaalsContact C-N 3.33Å; A410-Y412 PolarHBondContact O-N 3.42Å; Y412-V414 PolarHBondContact O-N 2.79Å; Y412-F415 PolarHBondContact O-N 2.71Å; Y412-L416 HydrophobicContact CE1-CB 4.46Å; Y412-L416 HydrophobicContact CE1-CD2 3.94Å; Y412-L416 WeakPolarHBondContact O-CB 3.24Å; Y412-L416 PolarHBondContact O-N 2.85Å
413F91.8Very high91.8Very high126 Ų12663.7 Ų63.755%0.55334%0.343SS*.Hα-helixtrans-62.2-41.5178.9-83.4-66.9000112.3A409 A410 V411 L416 C417A409-F413 WeakPolarHBondContact O-CD2 3.5Å; A409-F413 PolarHBondContact O-N 2.96Å; A410-F413 PolarHBondContact O-N 2.92Å; V411-F413 PolarHBondContact O-N 2.78Å; F413-L416 PolarHBondContact O-N 3.43Å; F413-C417 WeakPolarHBondContact O-CB 3.32Å; F413-C417 PolarHBondContact O-N 2.85Å; F413-C417 PolarHBondContact O-SG 2.86Å
414V92Very high91.3Very high97 Ų9763.5 Ų63.559%0.58834%0.341SS*.Hα-helixtrans-60.7-46.7175.3172.10000110.7A410 V411 Y412 C417 F418A410-V414 WeakPolarHBondContact O-CG2 3.35Å; A410-V414 PolarHBondContact O-N 3.35Å; V411-V414 PolarHBondContact O-N 2.03Å; Y412-V414 PolarHBondContact O-N 2.79Å; V414-C417 PolarHBondContact O-N 3.04Å; V414-F418 WeakPolarHBondContact O-CB 3.47Å; V414-F418 PolarHBondContact O-N 3.46Å
415F89.3Confident90.9Very high72 Ų7262.5 Ų62.532%0.31634%0.343SS..Hα-helixtrans-63.6-44.3177.2-72-38.7000112.8V411 Y412 F418 L419V411-F415 HydrophobicContact CG1-CD2 3.68Å; V411-F415 HydrophobicContact CG1-CE2 3.25Å; V411-F415 HydrophobicContact CG1-CZ 3.92Å; V411-F415 WeakPolarHBondContact O-CD2 3.18Å; V411-F415 WeakPolarHBondContact O-CG 3.34Å; V411-F415 PolarHBondContact O-N 2.89Å; Y412-F415 PolarHBondContact O-N 2.71Å; F415-F418 PolarHBondContact O-N 3.28Å; F415-L419 WeakPolarHBondContact O-CB 3.08Å; F415-L419 VanDerWaalsContact O-CG 3.32Å; F415-L419 WeakPolarHBondContact O-CG 3.27Å; F415-L419 PolarHBondContact O-N 3.05Å
416L90.4Very high90.4Very high22 Ų2263.4 Ų63.412%0.11535%0.348CS..Hα-helixtrans-62.4-46.2177.9-175.265.8000110.7W335 L336 Y412 F413 F418 L419 L420W335-L416 HydrophobicContact CB-CD1 4.4Å; L336-L416 HydrophobicContact CD2-CB 4.24Å; L336-L416 HydrophobicContact CD2-CD1 4.09Å; Y412-L416 HydrophobicContact CE1-CB 4.46Å; Y412-L416 HydrophobicContact CE1-CD2 3.94Å; Y412-L416 WeakPolarHBondContact O-CB 3.24Å; Y412-L416 PolarHBondContact O-N 2.85Å; F413-L416 PolarHBondContact O-N 3.43Å; L416-F418 PolarHBondContact O-N 3.02Å; L416-L419 PolarHBondContact O-N 2.93Å; L416-L420 HydrophobicContact CD1-CG 4.49Å; L416-L420 HydrophobicContact CG-CD1 4.14Å; L416-L420 HydrophobicContact CG-CG 4.46Å; L416-L420 WeakPolarHBondContact O-CB 3.32Å; L416-L420 VanDerWaalsContact O-CG 3.23Å; L416-L420 WeakPolarHBondContact O-CG 3.47Å; L416-L420 PolarHBondContact O-N 2.96Å
417C91.2Very high89.8Confident68 Ų6859.8 Ų59.846%0.45933%0.326SS..Hα-helixtrans-60.3-46.1176.9-70.20000111.6F413 V414 L419 L420 L421F413-C417 WeakPolarHBondContact O-CB 3.32Å; F413-C417 PolarHBondContact O-N 2.85Å; F413-C417 PolarHBondContact O-SG 2.86Å; V414-C417 PolarHBondContact O-N 3.04Å; C417-L419 PolarHBondContact O-N 3.36Å; C417-L420 PolarHBondContact O-N 3.49Å; C417-L421 WeakPolarHBondContact O-CB 3.26Å; C417-L421 VanDerWaalsContact O-CG 3.29Å; C417-L421 WeakPolarHBondContact O-CG 3.39Å; C417-L421 PolarHBondContact O-N 3.29Å
418F89.6Confident89.3Confident116 Ų11663.3 Ų63.351%0.50934%0.337SS..Hα-helixtrans-59.4-46.3176.5175.4-101.3000112.1V414 F415 L416 L421 R422V414-F418 WeakPolarHBondContact O-CB 3.47Å; V414-F418 PolarHBondContact O-N 3.46Å; F415-F418 PolarHBondContact O-N 3.28Å; L416-F418 PolarHBondContact O-N 3.02Å; F418-L421 PolarHBondContact O-N 3.28Å; F418-R422 VanDerWaalsContact CE1-CD 3.44Å; F418-R422 HydrophobicContact CE1-CG 4.18Å; F418-R422 HydrophobicContact CE2-CG 4.32Å; F418-R422 VanDerWaalsContact CZ-CD 3.47Å; F418-R422 HydrophobicContact CZ-CG 4.07Å; F418-R422 WeakPolarHBondContact O-CG 3.3Å; F418-R422 PolarHBondContact O-N 2.92Å
419L87.1Confident88.8Confident13 Ų1368.9 Ų68.97%0.06836%0.362CS..Hα-helixtrans-61.1-46176.4-75.4169.5000111.4L336 A339 L343 F415 L416 C417 L421 R422 V423L336-L419 HydrophobicContact CD2-CD1 3.78Å; A339-L419 HydrophobicContact CB-CB 4.3Å; L343-L419 HydrophobicContact CD1-CD2 3.74Å; F415-L419 WeakPolarHBondContact O-CB 3.08Å; F415-L419 VanDerWaalsContact O-CG 3.32Å; F415-L419 WeakPolarHBondContact O-CG 3.27Å; F415-L419 PolarHBondContact O-N 3.05Å; L416-L419 PolarHBondContact O-N 2.93Å; C417-L419 PolarHBondContact O-N 3.36Å; L419-L421 PolarHBondContact O-N 3.38Å; L419-R422 PolarHBondContact O-N 2.74Å; L419-V423 VanDerWaalsContact O-CG2 3.31Å; L419-V423 WeakPolarHBondContact O-CG2 3.25Å; L419-V423 PolarHBondContact O-N 2.83Å
420L88.3Confident88.1Confident53 Ų5367.6 Ų67.628%0.27735%0.349SS..Hα-helixtrans-61.2-44.1177.9-70.9176.4000111.9A339 L416 C417 R422 V423 M424 F452 M456A339-L420 HydrophobicContact CB-CD2 4.41Å; L416-L420 HydrophobicContact CD1-CG 4.49Å; L416-L420 HydrophobicContact CG-CD1 4.14Å; L416-L420 HydrophobicContact CG-CG 4.46Å; L416-L420 WeakPolarHBondContact O-CB 3.32Å; L416-L420 VanDerWaalsContact O-CG 3.23Å; L416-L420 WeakPolarHBondContact O-CG 3.47Å; L416-L420 PolarHBondContact O-N 2.96Å; C417-L420 PolarHBondContact O-N 3.49Å; L420-R422 PolarHBondContact O-N 3.2Å; L420-V423 PolarHBondContact O-N 3.11Å; L420-M424 WeakPolarHBondContact O-CB 3.06Å; L420-M424 WeakPolarHBondContact O-CG 3.05Å; L420-M424 PolarHBondContact O-N 3.25Å; L420-F452 HydrophobicContact CD2-CZ 4.08Å; L420-M456 HydrophobicContact CD2-CE 3.8Å
421L89.4Confident87.5Confident124 Ų12469.5 Ų69.565%0.64935%0.347SS*.Hα-helixtrans-61.5-43.3175.6-71.4173.9000111.7C417 F418 L419 M424 A425C417-L421 WeakPolarHBondContact O-CB 3.26Å; C417-L421 VanDerWaalsContact O-CG 3.29Å; C417-L421 WeakPolarHBondContact O-CG 3.39Å; C417-L421 PolarHBondContact O-N 3.29Å; F418-L421 PolarHBondContact O-N 3.28Å; L419-L421 PolarHBondContact O-N 3.38Å; L421-M424 PolarHBondContact O-N 2.81Å; L421-A425 WeakPolarHBondContact O-CB 3.2Å; L421-A425 PolarHBondContact O-N 2.83Å
422R88.4Confident87Confident106 Ų10671.2 Ų71.240%0.436%0.362SS..Hα-helixtrans-61.4-46.4174.7-76.9-166.369.6-170.51111.8L343 D345 F418 L419 L420 M424 A425 T426L343-R422 HydrophobicContact CD2-CB 3.87Å; D345-R422 IonicContact OD2-NH2 3.88Å; F418-R422 VanDerWaalsContact CE1-CD 3.44Å; F418-R422 HydrophobicContact CE1-CG 4.18Å; F418-R422 HydrophobicContact CE2-CG 4.32Å; F418-R422 VanDerWaalsContact CZ-CD 3.47Å; F418-R422 HydrophobicContact CZ-CG 4.07Å; F418-R422 WeakPolarHBondContact O-CG 3.3Å; F418-R422 PolarHBondContact O-N 2.92Å; L419-R422 PolarHBondContact O-N 2.74Å; L420-R422 PolarHBondContact O-N 3.2Å; R422-M424 VanDerWaalsContact C-N 3.31Å; R422-M424 PolarHBondContact O-N 2.92Å; R422-A425 PolarHBondContact O-N 2.95Å; R422-T426 WeakPolarHBondContact O-CB 3.48Å; R422-T426 PolarHBondContact O-N 3.25Å; R422-T426 PolarHBondContact O-OG1 3.35Å
423V85.5Confident86.4Confident0 Ų073 Ų730%038%0.376CS..Hα-helixtrans-62.1-42.1178.11800000110.5A339 H342 L343 L419 L420 A425 T426 I427 F452A339-V423 VanDerWaalsContact O-CG2 3.25Å; A339-V423 WeakPolarHBondContact O-CG2 3.5Å; H342-V423 HydrophobicContact CB-CG1 4.48Å; L343-V423 HydrophobicContact CD2-CB 4.24Å; L343-V423 HydrophobicContact CD2-CG2 3.47Å; L343-V423 VanDerWaalsContact CD2-CG2 3.47Å; L343-V423 HydrophobicContact CG-CG2 3.64Å; L419-V423 VanDerWaalsContact O-CG2 3.31Å; L419-V423 WeakPolarHBondContact O-CG2 3.25Å; L419-V423 PolarHBondContact O-N 2.83Å; L420-V423 PolarHBondContact O-N 3.11Å; V423-A425 PolarHBondContact O-N 2.9Å; V423-T426 PolarHBondContact O-N 2.72Å; V423-I427 HydrophobicContact CG1-CD1 3.67Å; V423-I427 HydrophobicContact CG1-CG1 4.14Å; V423-I427 WeakPolarHBondContact O-CB 3.28Å; V423-I427 VanDerWaalsContact O-CG1 3.23Å; V423-I427 WeakPolarHBondContact O-CG1 3.48Å; V423-I427 PolarHBondContact O-N 2.95Å; V423-F452 HydrophobicContact CB-CE1 4.05Å; V423-F452 HydrophobicContact CB-CE2 4.37Å; V423-F452 HydrophobicContact CB-CZ 3.7Å; V423-F452 HydrophobicContact CG1-CD1 3.87Å; V423-F452 HydrophobicContact CG1-CD2 4.25Å; V423-F452 HydrophobicContact CG1-CE1 3.27Å; V423-F452 HydrophobicContact CG1-CE2 3.77Å; V423-F452 HydrophobicContact CG1-CG 4.3Å; V423-F452 HydrophobicContact CG1-CZ 3.24Å; V423-F452 HydrophobicContact CG2-CE2 4.43Å; V423-F452 HydrophobicContact CG2-CZ 4.18Å
424M85.6Confident85.8Confident89 Ų8967.7 Ų67.744%0.43835%0.353SS..Hα-helixtrans-63.6-40.8177.4-70.5-66.7-78.100112.3L420 L421 R422 I427 K428 F452 M456L420-M424 WeakPolarHBondContact O-CB 3.06Å; L420-M424 WeakPolarHBondContact O-CG 3.05Å; L420-M424 PolarHBondContact O-N 3.25Å; L421-M424 PolarHBondContact O-N 2.81Å; R422-M424 VanDerWaalsContact C-N 3.31Å; R422-M424 PolarHBondContact O-N 2.92Å; M424-I427 PolarHBondContact O-N 3.05Å; M424-K428 WeakPolarHBondContact O-CB 3.35Å; M424-K428 PolarHBondContact O-N 3.41Å; M424-F452 HydrophobicContact SD-CE1 4.47Å; M424-M456 HydrophobicContact SD-CE 4.33Å
425A87.2Confident85Confident51 Ų5169 Ų6942%0.42136%0.357SS..Hα-helixtrans-63.2-46.517400000111.7L421 R422 V423 K428 Q429L421-A425 WeakPolarHBondContact O-CB 3.2Å; L421-A425 PolarHBondContact O-N 2.83Å; R422-A425 PolarHBondContact O-N 2.95Å; V423-A425 PolarHBondContact O-N 2.9Å; A425-K428 WeakPolarHBondContact O-CB 3.46Å; A425-K428 PolarHBondContact O-N 3.21Å; A425-Q429 WeakPolarHBondContact O-CG 3.27Å; A425-Q429 PolarHBondContact O-N 3.23Å
426T83.4Confident84.8Confident29 Ų2972 Ų7218%0.17838%0.381CS..Hα-helixtrans-60.7-46.4176.3-58.80000111.2I344 R422 V423 K428 Q429 T430I344-T426 HydrophobicContact CB-CG2 4.05Å; I344-T426 HydrophobicContact CD1-CG2 3.68Å; I344-T426 HydrophobicContact CG1-CG2 3.84Å; R422-T426 WeakPolarHBondContact O-CB 3.48Å; R422-T426 PolarHBondContact O-N 3.25Å; R422-T426 PolarHBondContact O-OG1 3.35Å; V423-T426 PolarHBondContact O-N 2.72Å; T426-K428 VanDerWaalsContact C-N 3.28Å; T426-K428 PolarHBondContact O-N 3.43Å; T426-Q429 PolarHBondContact O-N 2.68Å; T426-Q429 VanDerWaalsContact O-N 3.16Å; T426-T430 PolarHBondContact O-N 3.14Å; T426-T430 PolarHBondContact O-OG1 3.49Å
427I82.9Confident84.3Confident17 Ų1773.4 Ų73.49%0.08739%0.387CS..Hα-helixtrans-59.8-39.9176.2-70.8172000110.9V423 M424 K431 I449 F452V423-I427 HydrophobicContact CG1-CD1 3.67Å; V423-I427 HydrophobicContact CG1-CG1 4.14Å; V423-I427 WeakPolarHBondContact O-CB 3.28Å; V423-I427 VanDerWaalsContact O-CG1 3.23Å; V423-I427 WeakPolarHBondContact O-CG1 3.48Å; V423-I427 PolarHBondContact O-N 2.95Å; M424-I427 PolarHBondContact O-N 3.05Å; I427-K431 HydrophobicContact CG2-CD 4.11Å; I427-K431 HydrophobicContact CG2-CG 4.34Å; I427-K431 VanDerWaalsContact O-CB 3.28Å; I427-K431 WeakPolarHBondContact O-CB 2.96Å; I427-K431 VanDerWaalsContact O-CG 3.22Å; I427-K431 WeakPolarHBondContact O-CG 3.15Å; I427-K431 PolarHBondContact O-N 3Å; I427-I449 HydrophobicContact CG1-CG1 4.35Å; I427-I449 HydrophobicContact CG2-CD1 4.3Å; I427-I449 HydrophobicContact CG2-CG1 4.29Å; I427-I449 HydrophobicContact CG2-CG2 3.89Å; I427-F452 HydrophobicContact CD1-CD1 3.38Å; I427-F452 HydrophobicContact CD1-CE1 3.73Å; I427-F452 HydrophobicContact CD1-CG 4.28Å
428K85.8Confident84Confident167 Ų16778.8 Ų78.873%0.72640%0.403SS*.Hα-helixtrans-62.1-44.4176.5-173.7-178.6178.2-176.40111.2M424 A425 T426 S432M424-K428 WeakPolarHBondContact O-CB 3.35Å; M424-K428 PolarHBondContact O-N 3.41Å; A425-K428 WeakPolarHBondContact O-CB 3.46Å; A425-K428 PolarHBondContact O-N 3.21Å; T426-K428 VanDerWaalsContact C-N 3.28Å; T426-K428 PolarHBondContact O-N 3.43Å; K428-S432 PolarHBondContact O-N 2.92Å
429Q83.4Confident83.5Confident134 Ų13483.6 Ų83.663%0.62642%0.418SS*.Hα-helixtrans-65-51.3176.4-70.3174.4-14.400111.7A425 T426 K431 S432A425-Q429 WeakPolarHBondContact O-CG 3.27Å; A425-Q429 PolarHBondContact O-N 3.23Å; T426-Q429 PolarHBondContact O-N 2.68Å; T426-Q429 VanDerWaalsContact O-N 3.16Å; Q429-K431 VanDerWaalsContact C-N 3.26Å; Q429-K431 PolarHBondContact O-N 2.79Å; Q429-S432 WeakPolarHBondContact O-CB 3.39Å; Q429-S432 PolarHBondContact O-N 3.04Å; Q429-S432 PolarHBondContact O-OG 3.07Å
430T78.3Confident82.8Confident15 Ų1585.6 Ų85.69%0.09244%0.442CS..Hα-helixtrans-59.3-38.8179.5-51.40000111.7I344 T426 S432 S433 L434 M437 F445I344-T430 HydrophobicContact CD1-CG2 4.1Å; I344-T430 WeakPolarHBondContact CD1-OG1 3.44Å; T426-T430 PolarHBondContact O-N 3.14Å; T426-T430 PolarHBondContact O-OG1 3.49Å; T430-S432 VanDerWaalsContact C-N 3.27Å; T430-S432 PolarHBondContact O-N 2.94Å; T430-S433 PolarHBondContact O-N 3.25Å; T430-S433 PolarHBondContact O-OG 2.72Å; T430-L434 PolarHBondContact O-N 2.81Å; T430-L434 VanDerWaalsContact O-N 3.13Å; T430-M437 HydrophobicContact CG2-CE 4.39Å; T430-F445 HydrophobicContact CG2-CD1 4.34Å
431K81.9Confident82.1Confident93 Ų9387.5 Ų87.540%0.40445%0.445SS..Hα-helixtrans-59.1-35.7176.1-82.2-177.3173.7-156.30113.7I427 Q429 S433 L434 I449I427-K431 HydrophobicContact CG2-CD 4.11Å; I427-K431 HydrophobicContact CG2-CG 4.34Å; I427-K431 VanDerWaalsContact O-CB 3.28Å; I427-K431 WeakPolarHBondContact O-CB 2.96Å; I427-K431 VanDerWaalsContact O-CG 3.22Å; I427-K431 WeakPolarHBondContact O-CG 3.15Å; I427-K431 PolarHBondContact O-N 3Å; Q429-K431 VanDerWaalsContact C-N 3.26Å; Q429-K431 PolarHBondContact O-N 2.79Å; K431-S433 PolarHBondContact O-N 3.24Å; K431-L434 HydrophobicContact CB-CD1 4.24Å; K431-L434 HydrophobicContact CG-CD1 3.86Å; K431-L434 PolarHBondContact O-N 2.74Å; K431-I449 HydrophobicContact CG-CD1 4.2Å
432S82.5Confident81.6Confident95 Ų9586 Ų8666%0.66443%0.431SS*.Hα-helixtrans-64.5-30.817674.60000112.4K428 Q429 T430K428-S432 PolarHBondContact O-N 2.92Å; Q429-S432 WeakPolarHBondContact O-CB 3.39Å; Q429-S432 PolarHBondContact O-N 3.04Å; Q429-S432 PolarHBondContact O-OG 3.07Å; T430-S432 VanDerWaalsContact C-N 3.27Å; T430-S432 PolarHBondContact O-N 2.94Å
433S81Confident81Confident45 Ų4584 Ų8432%0.31543%0.43SS..Hα-helixtrans-89.8-10.8-18065.70000115.2T430 K431 N435 V436 M437T430-S433 PolarHBondContact O-N 3.25Å; T430-S433 PolarHBondContact O-OG 2.72Å; K431-S433 PolarHBondContact O-N 3.24Å; S433-N435 PolarHBondContact O-N 3.4Å; S433-N435 VanDerWaalsContact O-N 3.15Å; S433-V436 PolarHBondContact O-N 3.06Å; S433-V436 VanDerWaalsContact O-N 3.1Å; S433-M437 WeakPolarHBondContact OG-CE 3.41Å
434L78.2Confident80.4Confident15 Ų1586.3 Ų86.38%0.07945%0.446CS..G310 helixtrans-57.3-33.6-173.9-82.8168.9000113.5T430 K431 V436 M437 R442 F445 E446 I449T430-L434 PolarHBondContact O-N 2.81Å; T430-L434 VanDerWaalsContact O-N 3.13Å; K431-L434 HydrophobicContact CB-CD1 4.24Å; K431-L434 HydrophobicContact CG-CD1 3.86Å; K431-L434 PolarHBondContact O-N 2.74Å; L434-V436 VanDerWaalsContact C-N 3.26Å; L434-V436 PolarHBondContact O-N 2.96Å; L434-M437 HydrophobicContact CD2-SD 4.39Å; L434-M437 PolarHBondContact O-N 3.48Å; L434-R442 HydrophobicContact CD2-CG 4.14Å; L434-F445 HydrophobicContact CD2-CB 3.96Å; L434-E446 HydrophobicContact CD1-CG 4.32Å; L434-E446 HydrophobicContact CD2-CG 4.23Å; L434-I449 HydrophobicContact CD1-CD1 4.45Å
435N76.9Confident80Confident125 Ų12583.3 Ų83.367%0.66843%0.431SS*.G310 helixtrans-71-21.1-177.1-70-26.2000113.3S433S433-N435 PolarHBondContact O-N 3.4Å; S433-N435 VanDerWaalsContact O-N 3.15Å
436V84Confident79.6Confident136 Ų13684.5 Ų84.582%0.82443%0.427SS*.G310 helixtrans-91.2-12.9-179.6-172.60000111.4S433 L434S433-V436 PolarHBondContact O-N 3.06Å; S433-V436 VanDerWaalsContact O-N 3.1Å; L434-V436 VanDerWaalsContact C-N 3.26Å; L434-V436 PolarHBondContact O-N 2.96Å
437M80.2Confident79.1Confident50 Ų5083.9 Ų83.925%0.24643%0.426CS..SBendtrans-78.9146.4-176.1-64.6-175.8-178.300113.1T430 S433 L434 R442 F445T430-M437 HydrophobicContact CG2-CE 4.39Å; S433-M437 WeakPolarHBondContact OG-CE 3.41Å; L434-M437 HydrophobicContact CD2-SD 4.39Å; L434-M437 PolarHBondContact O-N 3.48Å; M437-R442 HydrophobicContact CB-CB 4.33Å; M437-F445 HydrophobicContact CE-CD2 4.28Å; M437-F445 HydrophobicContact CE-CE2 4.13Å; M437-F445 HydrophobicContact SD-CD2 3.6Å; M437-F445 VanDerWaalsContact SD-CD2 3.6Å; M437-F445 HydrophobicContact SD-CE2 3.86Å
438K84.1Confident78.7Confident182 Ų18285.9 Ų85.979%0.79144%0.436SS*.  trans-54.2140.3168.9-67.7-177.4-179.8177.30110.5G440 R441 R442K438-G440 VanDerWaalsContact C-N 3.33Å; K438-G440 PolarHBondContact O-N 3.13Å; K438-G440 VanDerWaalsContact O-N 3.16Å; K438-R441 PolarHBondContact O-N 3.11Å; K438-R442 PolarHBondContact O-N 3.04Å
439R79.8Confident78.4Confident216 Ų21678.8 Ų78.882%0.81541%0.405SS*.Hα-helixtrans-49-46.2-173.5-173.4177.1-179.2172.30.6114.1R441 R442 V443R439-R441 PolarHBondContact O-N 3.49Å; R439-R442 PolarHBondContact O-N 2.92Å; R439-V443 WeakPolarHBondContact O-CG2 3.4Å; R439-V443 PolarHBondContact O-N 2.84Å; R439-V443 VanDerWaalsContact O-N 3.07Å
440G73.2Confident78.2Confident56 Ų5676.8 Ų76.858%0.57739%0.393SS*.Hα-helixtrans-62-42.8-179.800000113.2K438 C444K438-G440 VanDerWaalsContact C-N 3.33Å; K438-G440 PolarHBondContact O-N 3.13Å; K438-G440 VanDerWaalsContact O-N 3.16Å; G440-C444 PolarHBondContact O-N 3.04Å
441R73.3Confident78.2Confident93 Ų9377.3 Ų77.335%0.35139%0.393SS..Hα-helixtrans-70.3-38.4177.9-169.6172.2-173.9171.4-4.3112K438 R439 C444 F445K438-R441 PolarHBondContact O-N 3.11Å; R439-R441 PolarHBondContact O-N 3.49Å; R441-C444 PolarHBondContact O-N 3.42Å; R441-F445 HydrophobicContact CG-CD2 3.83Å; R441-F445 HydrophobicContact CG-CE2 3.71Å; R441-F445 WeakPolarHBondContact O-CD2 2.99Å; R441-F445 PolarHBondContact O-N 3.37Å
442R78.2Confident78.2Confident92 Ų9273 Ų7335%0.34737%0.374SS..Hα-helixtrans-58.2-49.2175.2-179-178.6168168.41.7111.7L434 M437 K438 R439 C444 F445 E446L434-R442 HydrophobicContact CD2-CG 4.14Å; M437-R442 HydrophobicContact CB-CB 4.33Å; K438-R442 PolarHBondContact O-N 3.04Å; R439-R442 PolarHBondContact O-N 2.92Å; R442-C444 VanDerWaalsContact C-N 3.31Å; R442-C444 PolarHBondContact O-N 3.46Å; R442-F445 PolarHBondContact O-N 3.13Å; R442-E446 HydrophobicContact CG-CG 4.38Å; R442-E446 IonicContact CZ-OE1 3.46Å; R442-E446 IonicContact NE-OE1 2.79Å; R442-E446 PolarHBondContact NE-OE1 2.9Å; R442-E446 IonicContact NH2-OE1 3.21Å; R442-E446 PolarHBondContact NH2-OE1 2.77Å; R442-E446 WeakPolarHBondContact O-CB 3.49Å; R442-E446 WeakPolarHBondContact O-CG 3.27Å; R442-E446 PolarHBondContact O-N 3.3Å
443V76.1Confident78.4Confident63 Ų6372.6 Ų72.638%0.38236%0.361SS..Hα-helixtrans-60.9-41.2179.1172.60000111.3R439 E446 A447R439-V443 WeakPolarHBondContact O-CG2 3.4Å; R439-V443 PolarHBondContact O-N 2.84Å; R439-V443 VanDerWaalsContact O-N 3.07Å; V443-E446 PolarHBondContact O-N 3.25Å; V443-A447 WeakPolarHBondContact O-CB 3.39Å; V443-A447 PolarHBondContact O-N 3.28Å
444C72.1Confident78.5Confident50 Ų5071.8 Ų71.834%0.33835%0.352SS..Hα-helixtrans-61.7-48.1176.4-1760000112.1G440 R441 R442 A447 I448G440-C444 PolarHBondContact O-N 3.04Å; R441-C444 PolarHBondContact O-N 3.42Å; R442-C444 VanDerWaalsContact C-N 3.31Å; R442-C444 PolarHBondContact O-N 3.46Å; C444-A447 PolarHBondContact O-N 3Å; C444-I448 WeakPolarHBondContact O-CG1 3.28Å; C444-I448 PolarHBondContact O-N 3.06Å
445F76.7Confident78.8Confident26 Ų2671.2 Ų71.211%0.11435%0.349CS..Hα-helixtrans-65.3-42177.2-84.3-63.9000113.2I344 T430 L434 M437 R441 R442 A447 I448 I449I344-F445 HydrophobicContact CD1-CE1 4.19Å; T430-F445 HydrophobicContact CG2-CD1 4.34Å; L434-F445 HydrophobicContact CD2-CB 3.96Å; M437-F445 HydrophobicContact CE-CD2 4.28Å; M437-F445 HydrophobicContact CE-CE2 4.13Å; M437-F445 HydrophobicContact SD-CD2 3.6Å; M437-F445 VanDerWaalsContact SD-CD2 3.6Å; M437-F445 HydrophobicContact SD-CE2 3.86Å; R441-F445 HydrophobicContact CG-CD2 3.83Å; R441-F445 HydrophobicContact CG-CE2 3.71Å; R441-F445 WeakPolarHBondContact O-CD2 2.99Å; R441-F445 PolarHBondContact O-N 3.37Å; R442-F445 PolarHBondContact O-N 3.13Å; F445-A447 PolarHBondContact O-N 3.46Å; F445-I448 PolarHBondContact O-N 3.11Å; F445-I449 WeakPolarHBondContact O-CG1 3.37Å; F445-I449 PolarHBondContact O-N 2.86Å
446E79.7Confident79.3Confident75 Ų7568 Ų6835%0.3533%0.33SS..Hα-helixtrans-57.8-40.7174.9-76.8177.817800110.9L434 R442 V443 I449 Y450L434-E446 HydrophobicContact CD1-CG 4.32Å; L434-E446 HydrophobicContact CD2-CG 4.23Å; R442-E446 HydrophobicContact CG-CG 4.38Å; R442-E446 IonicContact CZ-OE1 3.46Å; R442-E446 IonicContact NE-OE1 2.79Å; R442-E446 PolarHBondContact NE-OE1 2.9Å; R442-E446 IonicContact NH2-OE1 3.21Å; R442-E446 PolarHBondContact NH2-OE1 2.77Å; R442-E446 WeakPolarHBondContact O-CB 3.49Å; R442-E446 WeakPolarHBondContact O-CG 3.27Å; R442-E446 PolarHBondContact O-N 3.3Å; V443-E446 PolarHBondContact O-N 3.25Å; E446-I449 PolarHBondContact O-N 3.44Å; E446-Y450 VanDerWaalsContact O-CB 3.28Å; E446-Y450 WeakPolarHBondContact O-CB 3.46Å; E446-Y450 PolarHBondContact O-N 3.05Å
447A72.2Confident79.5Confident17 Ų1765.7 Ų65.714%0.1432%0.316CS..Hα-helixtrans-68.3-39.2177.200000113.5E15 V443 C444 F445 Y450 R451E15-A447 HydrophobicContact CG-CB 3.41Å; E15-A447 VanDerWaalsContact CG-CB 3.41Å; V443-A447 WeakPolarHBondContact O-CB 3.39Å; V443-A447 PolarHBondContact O-N 3.28Å; C444-A447 PolarHBondContact O-N 3Å; F445-A447 PolarHBondContact O-N 3.46Å; A447-Y450 PolarHBondContact O-N 2.89Å; A447-R451 WeakPolarHBondContact O-CG 3.31Å; A447-R451 PolarHBondContact O-N 2.58Å
448I75.1Confident79.9Confident59 Ų5965.1 Ų65.130%0.30331%0.313SS..Hα-helixtrans-62.8-47.2174.7-68166.1000110.5C444 F445 Y450 R451 F452C444-I448 WeakPolarHBondContact O-CG1 3.28Å; C444-I448 PolarHBondContact O-N 3.06Å; F445-I448 PolarHBondContact O-N 3.11Å; I448-Y450 VanDerWaalsContact C-N 3.28Å; I448-Y450 PolarHBondContact O-N 3.2Å; I448-R451 PolarHBondContact O-N 2.89Å; I448-F452 PolarHBondContact O-N 3.38Å
449I80Confident80.2Confident17 Ų1757.4 Ų57.49%0.08728%0.281CS..Hα-helixtrans-61.3-41.3177.4-67.6168.3000110.5I427 K431 L434 F445 E446 F452 K453I427-I449 HydrophobicContact CG1-CG1 4.35Å; I427-I449 HydrophobicContact CG2-CD1 4.3Å; I427-I449 HydrophobicContact CG2-CG1 4.29Å; I427-I449 HydrophobicContact CG2-CG2 3.89Å; K431-I449 HydrophobicContact CG-CD1 4.2Å; L434-I449 HydrophobicContact CD1-CD1 4.45Å; F445-I449 WeakPolarHBondContact O-CG1 3.37Å; F445-I449 PolarHBondContact O-N 2.86Å; E446-I449 PolarHBondContact O-N 3.44Å; I449-F452 PolarHBondContact O-N 2.97Å; I449-K453 HydrophobicContact CG2-CD 4.14Å; I449-K453 WeakPolarHBondContact O-CB 3.32Å; I449-K453 WeakPolarHBondContact O-CG 3.11Å; I449-K453 PolarHBondContact O-N 3.09Å
450Y78.6Confident80.7Confident92 Ų9255 Ų5536%0.36128%0.276SS..Hα-helixtrans-60.9-48177.5-177.7-97.9000111.9V14 M22 E446 A447 I448 F452 K453 F454V14-Y450 HydrophobicContact CG1-CD1 4.19Å; V14-Y450 HydrophobicContact CG1-CE1 4.31Å; M22-Y450 WeakPolarHBondContact CE-OH 3.45Å; M22-Y450 HydrophobicContact SD-CE1 3.87Å; M22-Y450 PolarHBondContact SD-OH 2.84Å; E446-Y450 VanDerWaalsContact O-CB 3.28Å; E446-Y450 WeakPolarHBondContact O-CB 3.46Å; E446-Y450 PolarHBondContact O-N 3.05Å; A447-Y450 PolarHBondContact O-N 2.89Å; I448-Y450 VanDerWaalsContact C-N 3.28Å; I448-Y450 PolarHBondContact O-N 3.2Å; Y450-F452 PolarHBondContact O-N 3.36Å; Y450-K453 PolarHBondContact O-N 2.96Å; Y450-F454 VanDerWaalsContact O-CB 3.28Å; Y450-F454 WeakPolarHBondContact O-CB 3.34Å; Y450-F454 PolarHBondContact O-N 2.76Å
451R78.4Confident81.6Confident26 Ų2656.5 Ų56.510%0.09827%0.27CS..Hα-helixtrans-57.5-49176.1-79.8-176.8-178.2136.615.6112.6S12 V14 E15 A447 I448 K453 F454 L455S12-R451 VanDerWaalsContact CB-CZ 3.5Å; S12-R451 PolarHBondContact OG-NE 2.82Å; S12-R451 PolarHBondContact OG-NH2 2.69Å; V14-R451 HydrophobicContact CB-CG 4.23Å; V14-R451 HydrophobicContact CG1-CG 3.7Å; E15-R451 IonicContact OE1-CZ 3.07Å; E15-R451 IonicContact OE1-NH1 2.74Å; E15-R451 PolarHBondContact OE1-NH1 2.78Å; E15-R451 IonicContact OE1-NH2 2.65Å; E15-R451 PolarHBondContact OE1-NH2 3.14Å; A447-R451 WeakPolarHBondContact O-CG 3.31Å; A447-R451 PolarHBondContact O-N 2.58Å; I448-R451 PolarHBondContact O-N 2.89Å; R451-K453 PolarHBondContact O-N 2.68Å; R451-F454 PolarHBondContact O-N 2.82Å; R451-L455 PolarHBondContact O-N 2.78Å
452F82.7Confident82.4Confident2 Ų252.2 Ų52.21%0.00926%0.255CS..Hα-helixtrans-59.6-48.4-179.9179.9-103.3000111.5F338 H342 L420 V423 M424 I427 I448 I449 Y450 L455 M456F338-F452 HydrophobicContact CD1-CD2 4.27Å; F338-F452 HydrophobicContact CD1-CE2 4.4Å; F338-F452 AromaticContact CE1-CD2 3.53Å; F338-F452 HydrophobicContact CE1-CD2 3.53Å; F338-F452 HydrophobicContact CE1-CE2 4.03Å; F338-F452 HydrophobicContact CE1-CG 4.49Å; F338-F452 HydrophobicContact CZ-CD2 4.19Å; H342-F452 HydrophobicContact CB-CD2 3.79Å; H342-F452 HydrophobicContact CB-CE2 4.28Å; H342-F452 HydrophobicContact CB-CG 4.41Å; H342-F452 AromaticContact CG-CD2 3.74Å; L420-F452 HydrophobicContact CD2-CZ 4.08Å; V423-F452 HydrophobicContact CB-CE1 4.05Å; V423-F452 HydrophobicContact CB-CE2 4.37Å; V423-F452 HydrophobicContact CB-CZ 3.7Å; V423-F452 HydrophobicContact CG1-CD1 3.87Å; V423-F452 HydrophobicContact CG1-CD2 4.25Å; V423-F452 HydrophobicContact CG1-CE1 3.27Å; V423-F452 HydrophobicContact CG1-CE2 3.77Å; V423-F452 HydrophobicContact CG1-CG 4.3Å; V423-F452 HydrophobicContact CG1-CZ 3.24Å; V423-F452 HydrophobicContact CG2-CE2 4.43Å; V423-F452 HydrophobicContact CG2-CZ 4.18Å; M424-F452 HydrophobicContact SD-CE1 4.47Å; I427-F452 HydrophobicContact CD1-CD1 3.38Å; I427-F452 HydrophobicContact CD1-CE1 3.73Å; I427-F452 HydrophobicContact CD1-CG 4.28Å; I448-F452 PolarHBondContact O-N 3.38Å; I449-F452 PolarHBondContact O-N 2.97Å; Y450-F452 PolarHBondContact O-N 3.36Å; F452-L455 PolarHBondContact O-N 3.18Å; F452-M456 HydrophobicContact CD1-CE 3.92Å; F452-M456 HydrophobicContact CE1-CE 3.04Å; F452-M456 HydrophobicContact CE2-CE 4.12Å; F452-M456 HydrophobicContact CZ-CE 3.14Å; F452-M456 VanDerWaalsContact O-CB 3.29Å; F452-M456 WeakPolarHBondContact O-CB 3.44Å; F452-M456 PolarHBondContact O-N 3.07Å
453K85.2Confident83Confident87 Ų8749.7 Ų49.738%0.37825%0.253SS..Hα-helixtrans-62.9-44.3177.8-77.3-176.9166.3-126.30112.5I449 Y450 R451 M456 V457I449-K453 HydrophobicContact CG2-CD 4.14Å; I449-K453 WeakPolarHBondContact O-CB 3.32Å; I449-K453 WeakPolarHBondContact O-CG 3.11Å; I449-K453 PolarHBondContact O-N 3.09Å; Y450-K453 PolarHBondContact O-N 2.96Å; R451-K453 PolarHBondContact O-N 2.68Å; K453-M456 PolarHBondContact O-N 2.91Å; K453-V457 WeakPolarHBondContact O-CG2 3.28Å; K453-V457 PolarHBondContact O-N 2.87Å
454F83.3Confident83.7Confident29 Ų2948.3 Ų48.313%0.12725%0.252CS..Hα-helixtrans-59.4-52.8178.5170.4-96000110.9F26 Y450 R451 M456 V457 F458 M515F26-F454 HydrophobicContact CD1-CE2 4.33Å; F26-F454 HydrophobicContact CD1-CZ 4.27Å; F26-F454 HydrophobicContact CE1-CE1 4.21Å; F26-F454 AromaticContact CE1-CE2 3.36Å; F26-F454 HydrophobicContact CE1-CE2 3.36Å; F26-F454 AromaticContact CE1-CZ 3.16Å; F26-F454 HydrophobicContact CE1-CZ 3.16Å; F26-F454 HydrophobicContact CE2-CD2 4.16Å; F26-F454 AromaticContact CE2-CE2 3.56Å; F26-F454 HydrophobicContact CE2-CE2 3.56Å; F26-F454 HydrophobicContact CE2-CZ 4.22Å; F26-F454 AromaticContact CZ-CD2 3.71Å; F26-F454 HydrophobicContact CZ-CD2 3.71Å; F26-F454 HydrophobicContact CZ-CE1 4.11Å; F26-F454 AromaticContact CZ-CE2 2.9Å; F26-F454 HydrophobicContact CZ-CE2 2.9Å; F26-F454 AromaticContact CZ-CZ 3.16Å; F26-F454 HydrophobicContact CZ-CZ 3.16Å; Y450-F454 VanDerWaalsContact O-CB 3.28Å; Y450-F454 WeakPolarHBondContact O-CB 3.34Å; Y450-F454 PolarHBondContact O-N 2.76Å; R451-F454 PolarHBondContact O-N 2.82Å; F454-M456 VanDerWaalsContact C-N 3.31Å; F454-M456 PolarHBondContact O-N 3.26Å; F454-V457 PolarHBondContact O-N 3.17Å; F454-F458 HydrophobicContact CE1-CB 4.36Å; F454-F458 HydrophobicContact CE1-CD1 4.38Å; F454-F458 HydrophobicContact CE2-CB 4.48Å; F454-F458 HydrophobicContact CZ-CB 4.06Å; F454-F458 HydrophobicContact CZ-CD1 4.28Å; F454-F458 HydrophobicContact CZ-CG 4.21Å; F454-F458 WeakPolarHBondContact O-CB 3.26Å; F454-F458 PolarHBondContact O-N 3.25Å; F454-M515 HydrophobicContact CD1-CE 3.36Å; F454-M515 HydrophobicContact CD1-SD 4Å; F454-M515 HydrophobicContact CE1-CE 3.32Å; F454-M515 HydrophobicContact CE1-SD 3.35Å; F454-M515 WeakPolarHBondContact CE1-SD 3.35Å; F454-M515 HydrophobicContact CG-CE 4.09Å; F454-M515 HydrophobicContact CZ-CE 4.04Å; F454-M515 HydrophobicContact CZ-SD 3.99Å
455L85.3Confident84.5Confident2 Ų249.6 Ų49.61%0.0126%0.255CS..Hα-helixtrans-65.2-38-177.9-174.959.5000111.7F334 F338 R451 F452 F458 T459 Y508 L512 Y516F334-L455 HydrophobicContact CE1-CD2 4.09Å; F334-L455 HydrophobicContact CZ-CD2 3.82Å; F338-L455 HydrophobicContact CD1-CD2 3.85Å; F338-L455 HydrophobicContact CD2-CD2 3.69Å; F338-L455 HydrophobicContact CE1-CB 4.08Å; F338-L455 HydrophobicContact CE1-CD2 3.57Å; F338-L455 HydrophobicContact CE1-CG 4.2Å; F338-L455 HydrophobicContact CE2-CD2 3.39Å; F338-L455 HydrophobicContact CG-CD2 3.92Å; F338-L455 HydrophobicContact CZ-CB 3.83Å; F338-L455 HydrophobicContact CZ-CD2 3.34Å; F338-L455 HydrophobicContact CZ-CG 4.12Å; R451-L455 PolarHBondContact O-N 2.78Å; F452-L455 PolarHBondContact O-N 3.18Å; L455-F458 HydrophobicContact CD1-CD1 4.45Å; L455-F458 PolarHBondContact O-N 3.04Å; L455-T459 VanDerWaalsContact O-CB 3.23Å; L455-T459 WeakPolarHBondContact O-CB 3.37Å; L455-T459 PolarHBondContact O-N 3.01Å; L455-T459 PolarHBondContact O-OG1 2.76Å; L455-Y508 HydrophobicContact CD1-CE2 4.12Å; L455-L512 HydrophobicContact CD1-CD2 3.41Å; L455-L512 VanDerWaalsContact CD1-CD2 3.41Å; L455-L512 HydrophobicContact CD1-CG 4.21Å; L455-L512 HydrophobicContact CD2-CD2 3.78Å; L455-L512 HydrophobicContact CG-CD2 4.24Å; L455-Y516 HydrophobicContact CD2-CE2 4.46Å
456M86.4Confident85.2Confident57 Ų5750.2 Ų50.228%0.28126%0.261SS..Hα-helixtrans-59.4-50.1175.9-178.1-173.3-59.500111.6L420 M424 F452 K453 F454 T459 F460L420-M456 HydrophobicContact CD2-CE 3.8Å; M424-M456 HydrophobicContact SD-CE 4.33Å; F452-M456 HydrophobicContact CD1-CE 3.92Å; F452-M456 HydrophobicContact CE1-CE 3.04Å; F452-M456 HydrophobicContact CE2-CE 4.12Å; F452-M456 HydrophobicContact CZ-CE 3.14Å; F452-M456 VanDerWaalsContact O-CB 3.29Å; F452-M456 WeakPolarHBondContact O-CB 3.44Å; F452-M456 PolarHBondContact O-N 3.07Å; K453-M456 PolarHBondContact O-N 2.91Å; F454-M456 VanDerWaalsContact C-N 3.31Å; F454-M456 PolarHBondContact O-N 3.26Å; M456-T459 PolarHBondContact O-N 2.88Å; M456-F460 WeakPolarHBondContact O-CB 3.35Å; M456-F460 PolarHBondContact O-N 2.79Å
457V88.1Confident85.6Confident89 Ų8950.7 Ų50.754%0.53927%0.269SS..Hα-helixtrans-63-45179.4171.70000110.7K453 F454 T459 F460 I461K453-V457 WeakPolarHBondContact O-CG2 3.28Å; K453-V457 PolarHBondContact O-N 2.87Å; F454-V457 PolarHBondContact O-N 3.17Å; V457-T459 PolarHBondContact O-N 3.06Å; V457-F460 PolarHBondContact O-N 3.47Å; V457-I461 HydrophobicContact CG1-CD1 3.9Å; V457-I461 WeakPolarHBondContact O-CG1 3.35Å; V457-I461 PolarHBondContact O-N 3.13Å
458F88.6Confident86.3Confident38 Ų3853.1 Ų53.117%0.16729%0.285CS..Hα-helixtrans-61.8-44.2179.2-175.9-139.2000111.8F454 L455 F460 I461 C462 Y508 C511F454-F458 HydrophobicContact CE1-CB 4.36Å; F454-F458 HydrophobicContact CE1-CD1 4.38Å; F454-F458 HydrophobicContact CE2-CB 4.48Å; F454-F458 HydrophobicContact CZ-CB 4.06Å; F454-F458 HydrophobicContact CZ-CD1 4.28Å; F454-F458 HydrophobicContact CZ-CG 4.21Å; F454-F458 WeakPolarHBondContact O-CB 3.26Å; F454-F458 PolarHBondContact O-N 3.25Å; L455-F458 HydrophobicContact CD1-CD1 4.45Å; L455-F458 PolarHBondContact O-N 3.04Å; F458-F460 PolarHBondContact O-N 2.82Å; F458-I461 PolarHBondContact O-N 3.18Å; F458-C462 PolarHBondContact O-N 3.3Å; F458-C462 PolarHBondContact O-SG 3.18Å; F458-C462 VanDerWaalsContact O-SG 3.36Å; F458-Y508 AromaticContact CD1-CD2 3.62Å; F458-Y508 HydrophobicContact CD1-CD2 3.62Å; F458-Y508 AromaticContact CD1-CE2 3.8Å; F458-Y508 HydrophobicContact CD1-CE2 3.8Å; F458-Y508 AromaticContact CE1-CD2 3.32Å; F458-Y508 HydrophobicContact CE1-CD2 3.32Å; F458-Y508 AromaticContact CE1-CE2 3.98Å; F458-Y508 HydrophobicContact CE1-CE2 3.98Å; F458-Y508 HydrophobicContact CE1-CG 4.1Å; F458-Y508 HydrophobicContact CG-CD2 4.42Å; F458-Y508 AromaticContact CZ-CD2 3.9Å; F458-Y508 HydrophobicContact CZ-CD2 3.9Å; F458-C511 HydrophobicContact CE1-CB 4.06Å
459T91.2Very high86.6Confident19 Ų1950.5 Ų50.512%0.11727%0.272CS..Hα-helixtrans-63.4-42176.9-55.70000111.6W335 L455 M456 V457 I461 C462 A463 Y508W335-T459 HydrophobicContact CD2-CG2 4.24Å; W335-T459 VanDerWaalsContact CE2-CG2 3.42Å; W335-T459 HydrophobicContact CH2-CG2 4.27Å; W335-T459 HydrophobicContact CZ2-CG2 3.44Å; W335-T459 VanDerWaalsContact CZ2-CG2 3.44Å; L455-T459 VanDerWaalsContact O-CB 3.23Å; L455-T459 WeakPolarHBondContact O-CB 3.37Å; L455-T459 PolarHBondContact O-N 3.01Å; L455-T459 PolarHBondContact O-OG1 2.76Å; M456-T459 PolarHBondContact O-N 2.88Å; V457-T459 PolarHBondContact O-N 3.06Å; T459-I461 PolarHBondContact O-N 3.36Å; T459-C462 PolarHBondContact O-N 2.69Å; T459-A463 WeakPolarHBondContact O-CB 3.41Å; T459-A463 PolarHBondContact O-N 3.09Å; T459-Y508 PolarHBondContact OG1-OH 2.76Å
460F91.2Very high86.7Confident165 Ų16556 Ų5672%0.72430%0.295SS*.Hα-helixtrans-62.8-41.5177.8-172.9-98.3000112M456 V457 F458 A463 G464M456-F460 WeakPolarHBondContact O-CB 3.35Å; M456-F460 PolarHBondContact O-N 2.79Å; V457-F460 PolarHBondContact O-N 3.47Å; F458-F460 PolarHBondContact O-N 2.82Å; F460-A463 PolarHBondContact O-N 3.02Å; F460-G464 PolarHBondContact O-N 2.85Å
461I90.5Very high87Confident89 Ų8955.6 Ų55.646%0.45630%0.299SS..Hα-helixtrans-62.7-47.9174.8-67.2166.7000110.5V457 F458 T459 A463 G464 L465V457-I461 HydrophobicContact CG1-CD1 3.9Å; V457-I461 WeakPolarHBondContact O-CG1 3.35Å; V457-I461 PolarHBondContact O-N 3.13Å; F458-I461 PolarHBondContact O-N 3.18Å; T459-I461 PolarHBondContact O-N 3.36Å; I461-A463 PolarHBondContact O-N 2.84Å; I461-G464 PolarHBondContact O-N 2.86Å; I461-L465 HydrophobicContact CG2-CD1 4.05Å; I461-L465 HydrophobicContact CG2-CG 4.46Å; I461-L465 WeakPolarHBondContact O-CG 3.32Å; I461-L465 PolarHBondContact O-N 2.65Å
462C91.4Very high86.9Confident3 Ų359.4 Ų59.42%0.0232%0.319CS..Hα-helixtrans-61.8-42.4178.5-69.30000112.5F458 T459 L465 T466 M504F458-C462 PolarHBondContact O-N 3.3Å; F458-C462 PolarHBondContact O-SG 3.18Å; F458-C462 VanDerWaalsContact O-SG 3.36Å; T459-C462 PolarHBondContact O-N 2.69Å; C462-L465 PolarHBondContact O-N 3.35Å; C462-T466 WeakPolarHBondContact O-CB 3.32Å; C462-T466 PolarHBondContact O-N 3.48Å; C462-T466 PolarHBondContact O-OG1 3.22Å; C462-M504 HydrophobicContact CB-CE 4.18Å; C462-M504 HydrophobicContact CB-CG 4.38Å; C462-M504 HydrophobicContact CB-SD 3.88Å; C462-M504 WeakPolarHBondContact O-CE 3.48Å
463A91.1Very high86.4Confident38 Ų3860.3 Ų60.331%0.31433%0.325SS..Hα-helixtrans-63.7-45.917600000111.4T459 F460 I461 L465 T466 V467T459-A463 WeakPolarHBondContact O-CB 3.41Å; T459-A463 PolarHBondContact O-N 3.09Å; F460-A463 PolarHBondContact O-N 3.02Å; I461-A463 PolarHBondContact O-N 2.84Å; A463-L465 PolarHBondContact O-N 3.05Å; A463-T466 WeakPolarHBondContact O-CB 3.34Å; A463-T466 PolarHBondContact O-N 2.75Å; A463-V467 WeakPolarHBondContact O-CG2 3.49Å; A463-V467 PolarHBondContact O-N 3.08Å
464G90.3Very high86.1Confident35 Ų3560.4 Ų60.436%0.36133%0.327SS..Hα-helixtrans-59.9-44.3176.800000112.9F460 I461 T466 V467 S468F460-G464 PolarHBondContact O-N 2.85Å; I461-G464 PolarHBondContact O-N 2.86Å; G464-T466 VanDerWaalsContact C-N 3.33Å; G464-T466 PolarHBondContact O-N 3.21Å; G464-V467 PolarHBondContact O-N 2.87Å; G464-S468 WeakPolarHBondContact O-CB 3.16Å; G464-S468 PolarHBondContact O-N 3.04Å; G464-S468 PolarHBondContact O-OG 3.18Å
465L88.6Confident85.5Confident77 Ų7763.5 Ų63.540%0.40334%0.344SS..Hα-helixtrans-63.7-37.9175.4-71.9174.8000112.4I461 C462 A463 A469 M504I461-L465 HydrophobicContact CG2-CD1 4.05Å; I461-L465 HydrophobicContact CG2-CG 4.46Å; I461-L465 WeakPolarHBondContact O-CG 3.32Å; I461-L465 PolarHBondContact O-N 2.65Å; C462-L465 PolarHBondContact O-N 3.35Å; A463-L465 PolarHBondContact O-N 3.05Å; L465-A469 VanDerWaalsContact O-CB 3.25Å; L465-A469 WeakPolarHBondContact O-CB 3.41Å; L465-A469 PolarHBondContact O-N 3.26Å; L465-M504 HydrophobicContact CB-CE 4.3Å; L465-M504 HydrophobicContact CB-SD 3.96Å; L465-M504 HydrophobicContact CD1-SD 3.9Å
466T90.4Very high84.5Confident39 Ų3965.1 Ų65.124%0.23936%0.361CS..Hα-helixtrans-64.7-45177.4-54.70000111.4C462 A463 G464 A469 F470 V501 M504C462-T466 WeakPolarHBondContact O-CB 3.32Å; C462-T466 PolarHBondContact O-N 3.48Å; C462-T466 PolarHBondContact O-OG1 3.22Å; A463-T466 WeakPolarHBondContact O-CB 3.34Å; A463-T466 PolarHBondContact O-N 2.75Å; G464-T466 VanDerWaalsContact C-N 3.33Å; G464-T466 PolarHBondContact O-N 3.21Å; T466-A469 PolarHBondContact O-N 3.05Å; T466-F470 PolarHBondContact O-N 3.19Å; T466-V501 HydrophobicContact CG2-CG1 4.18Å; T466-M504 WeakPolarHBondContact OG1-CE 3.36Å
467V90.1Very high83.4Confident85 Ų8566.7 Ų66.752%0.51537%0.367SS..Hα-helixtrans-66.3-43.8178.5174.30000111A463 G464 A469 F470 I471A463-V467 WeakPolarHBondContact O-CG2 3.49Å; A463-V467 PolarHBondContact O-N 3.08Å; G464-V467 PolarHBondContact O-N 2.87Å; V467-A469 VanDerWaalsContact C-N 3.32Å; V467-A469 PolarHBondContact O-N 2.83Å; V467-F470 PolarHBondContact O-N 2.93Å; V467-I471 HydrophobicContact CG1-CD1 3.85Å; V467-I471 HydrophobicContact CG1-CG1 4.45Å; V467-I471 WeakPolarHBondContact O-CG1 3.41Å; V467-I471 PolarHBondContact O-N 3.21Å
468S85.7Confident82Confident67 Ų6763.4 Ų63.447%0.46935%0.351SS..Hα-helixtrans-60.2-42.2175.5-62.80000112G464 I471 M472G464-S468 WeakPolarHBondContact O-CB 3.16Å; G464-S468 PolarHBondContact O-N 3.04Å; G464-S468 PolarHBondContact O-OG 3.18Å; S468-I471 PolarHBondContact O-N 3.15Å; S468-M472 VanDerWaalsContact O-CG 3.27Å; S468-M472 WeakPolarHBondContact O-CG 3.18Å; S468-M472 PolarHBondContact O-N 2.63Å
469A82Confident80.2Confident5 Ų567.7 Ų67.74%0.04137%0.372CS..Hα-helixtrans-61.5-46.8175.400000111.7L465 T466 V467 I471 M472 T473 F497 V501L465-A469 VanDerWaalsContact O-CB 3.25Å; L465-A469 WeakPolarHBondContact O-CB 3.41Å; L465-A469 PolarHBondContact O-N 3.26Å; T466-A469 PolarHBondContact O-N 3.05Å; V467-A469 VanDerWaalsContact C-N 3.32Å; V467-A469 PolarHBondContact O-N 2.83Å; A469-I471 PolarHBondContact O-N 2.93Å; A469-M472 PolarHBondContact O-N 3.38Å; A469-T473 PolarHBondContact O-N 2.88Å; A469-T473 PolarHBondContact O-OG1 3.16Å; A469-F497 HydrophobicContact CB-CB 3.98Å; A469-F497 HydrophobicContact CB-CD1 3.57Å; A469-F497 HydrophobicContact CB-CE1 4.35Å; A469-F497 HydrophobicContact CB-CG 3.95Å; A469-V501 HydrophobicContact CB-CG2 3.66Å
470F82.3Confident78.2Confident131 Ų13171.3 Ų71.358%0.57539%0.39SS*.Hα-helixtrans-58.7-47.9177.1177.7-98.4000112T466 V467 M472 T473 Q474T466-F470 PolarHBondContact O-N 3.19Å; V467-F470 PolarHBondContact O-N 2.93Å; F470-M472 VanDerWaalsContact C-N 3.32Å; F470-M472 PolarHBondContact O-N 2.59Å; F470-T473 PolarHBondContact O-N 3.34Å; F470-Q474 HydrophobicContact CD1-CG 4.21Å; F470-Q474 HydrophobicContact CD2-CG 4.47Å; F470-Q474 HydrophobicContact CE1-CG 3.79Å; F470-Q474 HydrophobicContact CE2-CG 4.07Å; F470-Q474 HydrophobicContact CZ-CG 3.71Å; F470-Q474 VanDerWaalsContact O-CG 3.3Å; F470-Q474 WeakPolarHBondContact O-CG 3.42Å; F470-Q474 PolarHBondContact O-N 2.69Å
471I83.6Confident76.1Confident85 Ų8573.2 Ų73.244%0.43639%0.392SS..Hα-helixtrans-60.1-44178.5-67.8167.7000110.7V467 S468 A469 Q474 I475V467-I471 HydrophobicContact CG1-CD1 3.85Å; V467-I471 HydrophobicContact CG1-CG1 4.45Å; V467-I471 WeakPolarHBondContact O-CG1 3.41Å; V467-I471 PolarHBondContact O-N 3.21Å; S468-I471 PolarHBondContact O-N 3.15Å; A469-I471 PolarHBondContact O-N 2.93Å; I471-Q474 PolarHBondContact O-N 3.35Å; I471-I475 HydrophobicContact CG2-CD1 3.68Å; I471-I475 HydrophobicContact CG2-CG1 4.39Å; I471-I475 VanDerWaalsContact O-CG1 3.26Å; I471-I475 WeakPolarHBondContact O-CG1 3.45Å; I471-I475 PolarHBondContact O-N 3.4Å
472M76.2Confident74Confident106 Ų10679 Ų7952%0.52241%0.409SS..Hα-helixtrans-64.6-40.8178.6-71.9-67.8-176.800112.5S468 A469 F470 I475 G476 F497S468-M472 VanDerWaalsContact O-CG 3.27Å; S468-M472 WeakPolarHBondContact O-CG 3.18Å; S468-M472 PolarHBondContact O-N 2.63Å; A469-M472 PolarHBondContact O-N 3.38Å; F470-M472 VanDerWaalsContact C-N 3.32Å; F470-M472 PolarHBondContact O-N 2.59Å; M472-I475 PolarHBondContact O-N 2.88Å; M472-G476 PolarHBondContact O-N 3.5Å; M472-F497 HydrophobicContact CB-CD2 3.98Å; M472-F497 HydrophobicContact CB-CE2 3.5Å; M472-F497 VanDerWaalsContact CB-CE2 3.5Å; M472-F497 HydrophobicContact CB-CZ 4.01Å; M472-F497 HydrophobicContact CG-CE2 3.97Å; M472-F497 HydrophobicContact CG-CZ 4Å
473T73.8Confident71.8Confident20 Ų2080.7 Ų80.712%0.12343%0.426CS..Hα-helixtrans-62.2-44.3174.6-630000111.2A469 F470 I475 G476 E477A469-T473 PolarHBondContact O-N 2.88Å; A469-T473 PolarHBondContact O-OG1 3.16Å; F470-T473 PolarHBondContact O-N 3.34Å; T473-I475 PolarHBondContact O-N 2.94Å; T473-G476 PolarHBondContact O-N 2.64Å; T473-E477 WeakPolarHBondContact O-CG 3.42Å; T473-E477 PolarHBondContact O-N 3.45Å
474Q77Confident69.5Low90 Ų9085.2 Ų85.242%0.42145%0.445SS..Hα-helixtrans-65.1-36.9177.9-69.7-62.9-37.900112.8F470 I471 G478F470-Q474 HydrophobicContact CD1-CG 4.21Å; F470-Q474 HydrophobicContact CD2-CG 4.47Å; F470-Q474 HydrophobicContact CE1-CG 3.79Å; F470-Q474 HydrophobicContact CE2-CG 4.07Å; F470-Q474 HydrophobicContact CZ-CG 3.71Å; F470-Q474 VanDerWaalsContact O-CG 3.3Å; F470-Q474 WeakPolarHBondContact O-CG 3.42Å; F470-Q474 PolarHBondContact O-N 2.69Å; I471-Q474 PolarHBondContact O-N 3.35Å; Q474-G478 WeakPolarHBondContact O-CA 3.47Å; Q474-G478 PolarHBondContact O-N 2.85Å
475I72.3Confident67.3Low94 Ų9491 Ų9148%0.48246%0.457SS..Hα-helixtrans-66.9-42174.5-68.4165.7000110.4I471 M472 T473 G478 Q479I471-I475 HydrophobicContact CG2-CD1 3.68Å; I471-I475 HydrophobicContact CG2-CG1 4.39Å; I471-I475 VanDerWaalsContact O-CG1 3.26Å; I471-I475 WeakPolarHBondContact O-CG1 3.45Å; I471-I475 PolarHBondContact O-N 3.4Å; M472-I475 PolarHBondContact O-N 2.88Å; T473-I475 PolarHBondContact O-N 2.94Å; I475-G478 WeakPolarHBondContact O-CA 3.04Å; I475-G478 PolarHBondContact O-N 2.85Å; I475-Q479 PolarHBondContact O-N 2.85Å
476G63.8Low65.1Low36 Ų3694.3 Ų94.337%0.37148%0.475SS..Hα-helixtrans-64.9-42.5176.900000113.1M472 T473 G478 Q479 L480M472-G476 PolarHBondContact O-N 3.5Å; T473-G476 PolarHBondContact O-N 2.64Å; G476-G478 VanDerWaalsContact C-N 3.28Å; G476-Q479 PolarHBondContact O-N 3.03Å; G476-L480 PolarHBondContact O-N 2.94Å
477E63.2Low62.7Low90 Ų90101.6 Ų101.642%0.42151%0.506SS..Hα-helixtrans-66.1-34.4171.3-72.7177.5-178.500111.7T473 L480T473-E477 WeakPolarHBondContact O-CG 3.42Å; T473-E477 PolarHBondContact O-N 3.45Å; E477-L480 VanDerWaalsContact O-CB 3.31Å; E477-L480 WeakPolarHBondContact O-CB 3.21Å; E477-L480 PolarHBondContact O-N 3.02Å
478G57.8Low60.3Low19 Ų19102.6 Ų102.620%0.19652%0.518CS..Hα-helixtrans-53.1-54.5170.300000110.7Q474 I475 G476 L480 R481Q474-G478 WeakPolarHBondContact O-CA 3.47Å; Q474-G478 PolarHBondContact O-N 2.85Å; I475-G478 WeakPolarHBondContact O-CA 3.04Å; I475-G478 PolarHBondContact O-N 2.85Å; G476-G478 VanDerWaalsContact C-N 3.28Å; G478-L480 PolarHBondContact O-N 2.9Å; G478-L480 VanDerWaalsContact O-N 3.16Å; G478-R481 WeakPolarHBondContact O-CA 3.45Å; G478-R481 VanDerWaalsContact O-CB 3.32Å; G478-R481 WeakPolarHBondContact O-CB 3.48Å; G478-R481 PolarHBondContact O-N 3.25Å
479Q52.3Low58.3Low128 Ų128103.5 Ų103.560%0.59852%0.522SS*.Hα-helixtrans-55-33.7179.7-70.7179.5-47.300113.2I475 G476 R481 W482I475-Q479 PolarHBondContact O-N 2.85Å; G476-Q479 PolarHBondContact O-N 3.03Å; Q479-R481 PolarHBondContact O-N 3.25Å; Q479-W482 PolarHBondContact O-N 3.05Å; Q479-W482 VanDerWaalsContact O-N 3.11Å
480L48.4Very low56.8Low95 Ų95110.1 Ų110.150%0.49756%0.562SS.*Hα-helixtrans-60.8-32.6173.9-160.879.3000112.7W50 G476 E477 G478 W482W50-L480 HydrophobicContact CZ2-CD1 4.5Å; W50-L480 VanDerWaalsContact NE1-CD1 3.32Å; G476-L480 PolarHBondContact O-N 2.94Å; E477-L480 VanDerWaalsContact O-CB 3.31Å; E477-L480 WeakPolarHBondContact O-CB 3.21Å; E477-L480 PolarHBondContact O-N 3.02Å; G478-L480 PolarHBondContact O-N 2.9Å; G478-L480 VanDerWaalsContact O-N 3.16Å; L480-W482 VanDerWaalsContact C-N 3.32Å
481R47.5Very low55.5Low206 Ų206106.9 Ų106.978%0.77755%0.55SS*.Hα-helixtrans-74.4-20.1177.6-58.9-17976.5158.53.9113.3G478 Q479G478-R481 WeakPolarHBondContact O-CA 3.45Å; G478-R481 VanDerWaalsContact O-CB 3.32Å; G478-R481 WeakPolarHBondContact O-CB 3.48Å; G478-R481 PolarHBondContact O-N 3.25Å; Q479-R481 PolarHBondContact O-N 3.25Å
482W46.5Very low55Low211 Ų211106 Ų10680%0.79954%0.544SS*.THydrogen-bonded Turntrans-95.42-176.8-60.187000113.6Q479 L480 D484Q479-W482 PolarHBondContact O-N 3.05Å; Q479-W482 VanDerWaalsContact O-N 3.11Å; L480-W482 VanDerWaalsContact C-N 3.32Å; W482-D484 VanDerWaalsContact C-N 3.26Å; W482-D484 PolarHBondContact O-N 2.85Å
483G45.3Very low55.1Low38 Ų38107.3 Ų107.339%0.39254%0.544SS..THydrogen-bonded Turntrans7114.5170.800000115.5Y485G483-Y485 WeakPolarHBondContact O-CD2 3.29Å; G483-Y485 PolarHBondContact O-N 2.86Å; G483-Y485 VanDerWaalsContact O-N 3.08Å
484D42.4Very low55.4Low133 Ų133108 Ų10871%0.71155%0.55SS**  trans-80.587.3173-77.7-23.4000109.6W482 D486W482-D484 VanDerWaalsContact C-N 3.26Å; W482-D484 PolarHBondContact O-N 2.85Å; D484-D486 PolarHBondContact O-N 2.83Å
485Y44.9Very low55.9Low156 Ų156103.8 Ų103.861%0.61253%0.53SS*.  trans-83.451.1172.6-63.3-90.9000111.8W50 G483 E487W50-Y485 AromaticContact CH2-CE1 3.79Å; W50-Y485 HydrophobicContact CH2-CE1 3.79Å; W50-Y485 AromaticContact CH2-CZ 3.68Å; W50-Y485 WeakPolarHBondContact CH2-OH 3.49Å; W50-Y485 AromaticContact CZ2-CE1 3.37Å; W50-Y485 HydrophobicContact CZ2-CE1 3.37Å; W50-Y485 AromaticContact CZ2-CZ 3.55Å; W50-Y485 WeakPolarHBondContact CZ2-OH 3.21Å; G483-Y485 WeakPolarHBondContact O-CD2 3.29Å; G483-Y485 PolarHBondContact O-N 2.86Å; G483-Y485 VanDerWaalsContact O-N 3.08Å; Y485-E487 PolarHBondContact O-N 2.86Å
486D41.7Very low56.7Low146 Ų14699.8 Ų99.878%0.78151%0.511SS*.  trans-83.3113173.1-85.1-16.3000110.1D484 S488D484-D486 PolarHBondContact O-N 2.83Å; D486-S488 PolarHBondContact O-N 2.88Å
487E39.3Very low57.8Low192 Ų192100.4 Ų100.490%0.89750%0.504SS*.  trans-5394.1166.6-70.6-175.5139.600110.7Y485Y485-E487 PolarHBondContact O-N 2.86Å
488S39.4Very low59Low107 Ų10799.4 Ų99.475%0.74850%0.501SS*.  trans162.2154.5148.941.70000112.6D486D486-S488 PolarHBondContact O-N 2.88Å
489P44.8Very low60.7Low85 Ų8598.5 Ų98.555%0.55249%0.492SS*.  cis-116.8171.62.435-18.1000113.2L491P489-L491 PolarHBondContact O-N 2.79Å
490T50Low62.6Low144 Ų14492.4 Ų92.488%0.88346%0.463SS*.SBendtrans-49.5-8.5-175.752.40000118.2
491L55.8Low64.7Low63 Ų6389.3 Ų89.333%0.3345%0.448SS..  trans-98.8118-178.2-162.488.7000110.4L42 P489 Y493L42-L491 HydrophobicContact CD2-CD1 3.91Å; P489-L491 PolarHBondContact O-N 2.79Å; L491-Y493 HydrophobicContact CD2-CD1 4.13Å; L491-Y493 HydrophobicContact CD2-CE1 3.67Å; L491-Y493 PolarHBondContact O-N 2.88Å
492Q71.8Confident66.8Low68 Ų6880.3 Ų80.332%0.31841%0.414SS..  trans-94.9102-177.8-65.7176.53.200110.7G41 A44 P45 S494 S495 A496G41-Q492 PolarHBondContact O-N 3.13Å; A44-Q492 PolarHBondContact O-OE1 3.15Å; P45-Q492 PolarHBondContact O-OE1 3.36Å; Q492-S494 PolarHBondContact O-N 2.77Å; Q492-S495 VanDerWaalsContact CB-OG 3.26Å; Q492-S495 WeakPolarHBondContact CB-OG 3.14Å; Q492-S495 PolarHBondContact O-OG 2.87Å; Q492-S495 VanDerWaalsContact O-OG 3.04Å; Q492-A496 WeakPolarHBondContact O-CB 3.42Å; Q492-A496 PolarHBondContact O-N 3.3Å; Q492-A496 VanDerWaalsContact O-N 3.08Å
493Y78.4Confident69.1Low133 Ų13370.3 Ų70.352%0.52238%0.376SS..Hα-helixtrans-62-43.7-174.9-62.7-75.7000111.9L491 S495 A496 F497L491-Y493 HydrophobicContact CD2-CD1 4.13Å; L491-Y493 HydrophobicContact CD2-CE1 3.67Å; L491-Y493 PolarHBondContact O-N 2.88Å; Y493-S495 PolarHBondContact O-N 2.9Å; Y493-A496 WeakPolarHBondContact O-CB 3.5Å; Y493-A496 PolarHBondContact O-N 3.14Å; Y493-F497 HydrophobicContact CD1-CE2 4.47Å; Y493-F497 WeakPolarHBondContact O-CB 3.33Å; Y493-F497 WeakPolarHBondContact O-CD2 3.45Å; Y493-F497 WeakPolarHBondContact O-CG 3.36Å; Y493-F497 PolarHBondContact O-N 3.26Å
494S81.8Confident71.4Confident35 Ų3568.8 Ų68.825%0.24536%0.359CS..Hα-helixtrans-62.4-45-175.7-170.50000112.7Q492 F497 L498Q492-S494 PolarHBondContact O-N 2.77Å; S494-F497 PolarHBondContact O-N 2.95Å; S494-L498 WeakPolarHBondContact O-CG 3.3Å; S494-L498 PolarHBondContact O-N 2.84Å; S494-L498 VanDerWaalsContact O-N 3.1Å
495S87.1Confident73.9Confident0 Ų063.6 Ų63.60%033%0.33CS..Hα-helixtrans-67.9-41.5175.255.50000112.1G40 A44 P45 Q492 Y493 F497 L498 T499G40-S495 PolarHBondContact O-OG 2.9Å; A44-S495 PolarHBondContact O-OG 3.25Å; P45-S495 WeakPolarHBondContact O-CB 3.32Å; Q492-S495 VanDerWaalsContact CB-OG 3.26Å; Q492-S495 WeakPolarHBondContact CB-OG 3.14Å; Q492-S495 PolarHBondContact O-OG 2.87Å; Q492-S495 VanDerWaalsContact O-OG 3.04Å; Y493-S495 PolarHBondContact O-N 2.9Å; S495-F497 VanDerWaalsContact C-N 3.3Å; S495-F497 PolarHBondContact O-N 2.9Å; S495-L498 PolarHBondContact O-N 2.94Å; S495-T499 WeakPolarHBondContact O-CG2 3.09Å; S495-T499 PolarHBondContact O-N 3.46Å; S495-T499 PolarHBondContact O-OG1 2.92Å
496A88.3Confident76.3Confident11 Ų1156.2 Ų56.29%0.09130%0.301CS..Hα-helixtrans-56.8-42.6175.300000112.5F37 Q492 Y493 T499 G500F37-A496 VanDerWaalsContact CD1-O 3.26Å; F37-A496 WeakPolarHBondContact CD1-O 3.44Å; Q492-A496 WeakPolarHBondContact O-CB 3.42Å; Q492-A496 PolarHBondContact O-N 3.3Å; Q492-A496 VanDerWaalsContact O-N 3.08Å; Y493-A496 WeakPolarHBondContact O-CB 3.5Å; Y493-A496 PolarHBondContact O-N 3.14Å; A496-T499 PolarHBondContact O-OG1 3.3Å; A496-G500 WeakPolarHBondContact O-CA 3.48Å; A496-G500 PolarHBondContact O-N 2.99Å
497F87.9Confident78.8Confident48 Ų4849.5 Ų49.521%0.21127%0.265CS..Hα-helixtrans-70.9-42.6179.5-77.1-56.3000112.1F37 A469 M472 Y493 S494 S495 G500 V501F37-F497 HydrophobicContact CE1-CD1 4.01Å; F37-F497 HydrophobicContact CE1-CE1 4.45Å; A469-F497 HydrophobicContact CB-CB 3.98Å; A469-F497 HydrophobicContact CB-CD1 3.57Å; A469-F497 HydrophobicContact CB-CE1 4.35Å; A469-F497 HydrophobicContact CB-CG 3.95Å; M472-F497 HydrophobicContact CB-CD2 3.98Å; M472-F497 HydrophobicContact CB-CE2 3.5Å; M472-F497 VanDerWaalsContact CB-CE2 3.5Å; M472-F497 HydrophobicContact CB-CZ 4.01Å; M472-F497 HydrophobicContact CG-CE2 3.97Å; M472-F497 HydrophobicContact CG-CZ 4Å; Y493-F497 HydrophobicContact CD1-CE2 4.47Å; Y493-F497 WeakPolarHBondContact O-CB 3.33Å; Y493-F497 WeakPolarHBondContact O-CD2 3.45Å; Y493-F497 WeakPolarHBondContact O-CG 3.36Å; Y493-F497 PolarHBondContact O-N 3.26Å; S494-F497 PolarHBondContact O-N 2.95Å; S495-F497 VanDerWaalsContact C-N 3.3Å; S495-F497 PolarHBondContact O-N 2.9Å; F497-G500 PolarHBondContact O-N 2.75Å; F497-V501 WeakPolarHBondContact O-CB 3.38Å; F497-V501 VanDerWaalsContact O-CG2 3.28Å; F497-V501 WeakPolarHBondContact O-CG2 3.35Å; F497-V501 PolarHBondContact O-N 3.31Å
498L87.9Confident81.3Confident70 Ų7040.4 Ų40.437%0.36622%0.223SC..Hα-helixtrans-62-49.7176.7-74174.3000112.1P47 F250 S494 S495 G500 Y502P47-L498 HydrophobicContact CB-CD1 3.66Å; P47-L498 HydrophobicContact CG-CD1 3.41Å; P47-L498 VanDerWaalsContact CG-CD1 3.41Å; F250-L498 HydrophobicContact CE2-CB 4.5Å; F250-L498 HydrophobicContact CE2-CD1 4.28Å; F250-L498 HydrophobicContact CZ-CB 4.24Å; F250-L498 HydrophobicContact CZ-CD1 3.8Å; S494-L498 WeakPolarHBondContact O-CG 3.3Å; S494-L498 PolarHBondContact O-N 2.84Å; S494-L498 VanDerWaalsContact O-N 3.1Å; S495-L498 PolarHBondContact O-N 2.94Å; L498-G500 VanDerWaalsContact C-N 3.34Å; L498-Y502 VanDerWaalsContact O-CB 3.28Å; L498-Y502 WeakPolarHBondContact O-CB 3.39Å; L498-Y502 PolarHBondContact O-N 3.4Å
499T92.4Very high83.9Confident0 Ų035.3 Ų35.30%019%0.187CC..Hα-helixtrans-66.3-39177.661.50000111.3F36 G40 W254 M257 S495 A496 Y502 G503F36-T499 WeakPolarHBondContact O-CB 3.44Å; F36-T499 PolarHBondContact O-OG1 3.33Å; G40-T499 WeakPolarHBondContact CA-OG1 3.5Å; G40-T499 PolarHBondContact N-OG1 3.14Å; W254-T499 HydrophobicContact CE3-CG2 4.47Å; M257-T499 WeakPolarHBondContact CE-O 3.28Å; M257-T499 HydrophobicContact SD-CG2 4.4Å; S495-T499 WeakPolarHBondContact O-CG2 3.09Å; S495-T499 PolarHBondContact O-N 3.46Å; S495-T499 PolarHBondContact O-OG1 2.92Å; A496-T499 PolarHBondContact O-OG1 3.3Å; T499-Y502 PolarHBondContact O-N 3.02Å; T499-G503 PolarHBondContact O-N 3.15Å
500G92.5Very high86.2Confident0 Ų033 Ų330%017%0.17CC..Hα-helixtrans-60.6-51.6176.900000112.5Q33 A496 F497 L498 Y502 G503 M504Q33-G500 PolarHBondContact NE2-O 3.43Å; A496-G500 WeakPolarHBondContact O-CA 3.48Å; A496-G500 PolarHBondContact O-N 2.99Å; F497-G500 PolarHBondContact O-N 2.75Å; L498-G500 VanDerWaalsContact C-N 3.34Å; G500-Y502 PolarHBondContact O-N 3.2Å; G500-G503 PolarHBondContact O-N 3.31Å; G500-M504 WeakPolarHBondContact O-CB 3.01Å; G500-M504 PolarHBondContact O-N 2.75Å
501V92.5Very high88.1Confident29 Ų2926.3 Ų26.318%0.17613%0.129CC..Hα-helixtrans-63.9-42.3178.9172.20000111.1T466 A469 F497 G503 M504 W505T466-V501 HydrophobicContact CG2-CG1 4.18Å; A469-V501 HydrophobicContact CB-CG2 3.66Å; F497-V501 WeakPolarHBondContact O-CB 3.38Å; F497-V501 VanDerWaalsContact O-CG2 3.28Å; F497-V501 WeakPolarHBondContact O-CG2 3.35Å; F497-V501 PolarHBondContact O-N 3.31Å; V501-G503 PolarHBondContact O-N 3.34Å; V501-M504 HydrophobicContact CG1-CE 4.44Å; V501-M504 WeakPolarHBondContact O-CB 2.99Å; V501-M504 PolarHBondContact O-N 2.9Å; V501-W505 PolarHBondContact O-N 3.4Å; V501-W505 VanDerWaalsContact O-N 3.09Å
502Y93.2Very high89.7Confident18 Ų1823.5 Ų23.57%0.07112%0.115CC..Hα-helixtrans-62-44176.7176.9-125.5000112.4W254 M257 K258 L261 M297 I300 D301 L498 T499 G500 M504 N506W254-Y502 HydrophobicContact CE3-CD1 4.38Å; W254-Y502 AromaticContact CH2-CD1 3.8Å; W254-Y502 HydrophobicContact CH2-CD1 3.8Å; W254-Y502 HydrophobicContact CH2-CD2 4.21Å; W254-Y502 AromaticContact CH2-CG 3.61Å; W254-Y502 HydrophobicContact CH2-CG 3.61Å; W254-Y502 HydrophobicContact CZ2-CD1 4.41Å; W254-Y502 HydrophobicContact CZ2-CG 4.34Å; W254-Y502 AromaticContact CZ3-CD1 3.78Å; W254-Y502 HydrophobicContact CZ3-CD1 3.78Å; W254-Y502 AromaticContact CZ3-CG 3.95Å; W254-Y502 HydrophobicContact CZ3-CG 3.95Å; M257-Y502 HydrophobicContact CE-CD1 3.3Å; M257-Y502 HydrophobicContact CE-CE1 3.82Å; M257-Y502 HydrophobicContact CE-CG 4.15Å; M257-Y502 HydrophobicContact CG-CD1 4.19Å; M257-Y502 HydrophobicContact CG-CE1 3.98Å; M257-Y502 HydrophobicContact SD-CD1 3.67Å; M257-Y502 HydrophobicContact SD-CE1 4.09Å; K258-Y502 HydrophobicContact CG-CE1 4.09Å; K258-Y502 WeakPolarHBondContact CG-OH 3.46Å; L261-Y502 HydrophobicContact CD1-CD1 4.47Å; L261-Y502 HydrophobicContact CD1-CE1 3.82Å; M297-Y502 HydrophobicContact CE-CD2 4.46Å; M297-Y502 HydrophobicContact CE-CE2 4.08Å; I300-Y502 HydrophobicContact CG2-CE2 3.79Å; D301-Y502 WeakPolarHBondContact OD1-CE2 3.46Å; D301-Y502 VanDerWaalsContact OD1-CZ 3.26Å; D301-Y502 PolarHBondContact OD1-OH 2.87Å; L498-Y502 VanDerWaalsContact O-CB 3.28Å; L498-Y502 WeakPolarHBondContact O-CB 3.39Å; L498-Y502 PolarHBondContact O-N 3.4Å; T499-Y502 PolarHBondContact O-N 3.02Å; G500-Y502 PolarHBondContact O-N 3.2Å; Y502-M504 VanDerWaalsContact C-N 3.33Å; Y502-M504 PolarHBondContact O-N 3.24Å; Y502-N506 WeakPolarHBondContact CE2-ND2 3.42Å; Y502-N506 PolarHBondContact O-N 2.93Å; Y502-N506 PolarHBondContact O-ND2 2.66Å
503G93.8Very high90.7Very high0 Ų020.3 Ų20.30%010%0.1CC..Hα-helixtrans-63.6-36.4173.800000113.3T499 G500 V501 N506 V507T499-G503 PolarHBondContact O-N 3.15Å; G500-G503 PolarHBondContact O-N 3.31Å; V501-G503 PolarHBondContact O-N 3.34Å; G503-N506 WeakPolarHBondContact O-CB 3.43Å; G503-N506 PolarHBondContact O-N 3.05Å; G503-V507 WeakPolarHBondContact O-CB 3.39Å; G503-V507 WeakPolarHBondContact O-CG2 3.35Å; G503-V507 PolarHBondContact O-N 2.74Å
504M94.1Very high91Very high6 Ų615.8 Ų15.83%0.039%0.089CC..Hα-helixtrans-64.4-45.8178.4-176.2176.563.100112.3Q33 C462 L465 T466 G500 V501 Y502 N506 V507 Y508Q33-M504 VanDerWaalsContact OE1-N 3.16Å; C462-M504 HydrophobicContact CB-CE 4.18Å; C462-M504 HydrophobicContact CB-CG 4.38Å; C462-M504 HydrophobicContact CB-SD 3.88Å; C462-M504 WeakPolarHBondContact O-CE 3.48Å; L465-M504 HydrophobicContact CB-CE 4.3Å; L465-M504 HydrophobicContact CB-SD 3.96Å; L465-M504 HydrophobicContact CD1-SD 3.9Å; T466-M504 WeakPolarHBondContact OG1-CE 3.36Å; G500-M504 WeakPolarHBondContact O-CB 3.01Å; G500-M504 PolarHBondContact O-N 2.75Å; V501-M504 HydrophobicContact CG1-CE 4.44Å; V501-M504 WeakPolarHBondContact O-CB 2.99Å; V501-M504 PolarHBondContact O-N 2.9Å; Y502-M504 VanDerWaalsContact C-N 3.33Å; Y502-M504 PolarHBondContact O-N 3.24Å; M504-N506 VanDerWaalsContact C-N 3.3Å; M504-N506 PolarHBondContact O-N 3.37Å; M504-V507 PolarHBondContact O-N 2.82Å; M504-Y508 VanDerWaalsContact O-CB 3.24Å; M504-Y508 WeakPolarHBondContact O-CB 3.13Å; M504-Y508 PolarHBondContact O-N 3.48Å
505W94.6Very high91.1Very high24 Ų2414.4 Ų14.49%0.0918%0.079CC..Hα-helixtrans-68.4-31.5178.1-72.9113000112.6M297 F327 L331 W335 V501 Y508 T509M297-W505 HydrophobicContact CE-CB 4.28Å; F327-W505 HydrophobicContact CE1-CB 4.37Å; F327-W505 HydrophobicContact CE1-CD2 4.17Å; F327-W505 HydrophobicContact CE1-CE3 4.31Å; F327-W505 HydrophobicContact CE1-CG 4.2Å; F327-W505 HydrophobicContact CZ-CB 4.08Å; F327-W505 HydrophobicContact CZ-CD2 4.18Å; F327-W505 AromaticContact CZ-CE3 3.98Å; F327-W505 HydrophobicContact CZ-CE3 3.98Å; F327-W505 HydrophobicContact CZ-CG 4.25Å; L331-W505 HydrophobicContact CD1-CZ3 3.93Å; L331-W505 HydrophobicContact CD2-CE3 3.99Å; L331-W505 HydrophobicContact CD2-CH2 3.56Å; L331-W505 HydrophobicContact CD2-CZ2 4.22Å; L331-W505 HydrophobicContact CD2-CZ3 3.42Å; L331-W505 VanDerWaalsContact CD2-CZ3 3.42Å; L331-W505 HydrophobicContact CG-CZ3 4.3Å; W335-W505 HydrophobicContact CH2-CH2 4.02Å; W335-W505 AromaticContact CZ2-CH2 3.79Å; W335-W505 HydrophobicContact CZ2-CH2 3.79Å; W335-W505 HydrophobicContact CZ2-CZ3 4.13Å; V501-W505 PolarHBondContact O-N 3.4Å; V501-W505 VanDerWaalsContact O-N 3.09Å; W505-Y508 AromaticContact CE3-CD1 3.94Å; W505-Y508 HydrophobicContact CE3-CD1 3.94Å; W505-Y508 HydrophobicContact CE3-CG 4.18Å; W505-Y508 AromaticContact CZ3-CD1 3.93Å; W505-Y508 HydrophobicContact CZ3-CD1 3.93Å; W505-Y508 HydrophobicContact CZ3-CE1 4.08Å; W505-Y508 HydrophobicContact CZ3-CG 4.24Å; W505-T509 WeakPolarHBondContact O-CB 3.28Å; W505-T509 PolarHBondContact O-N 2.89Å; W505-T509 PolarHBondContact O-OG1 2.83Å
506N95Very high90.9Very high1 Ų115.3 Ų15.31%0.0058%0.083CC..Hα-helixtrans-61.3-53.3169.1-101.5-75.3000111.4L261 M265 M297 D301 Y502 G503 M504 Y508 T509 L510L261-N506 HydrophobicContact CD1-CB 4.34Å; L261-N506 HydrophobicContact CD2-CB 4.49Å; M265-N506 HydrophobicContact CE-CB 4.47Å; M265-N506 WeakPolarHBondContact CE-OD1 3.29Å; M297-N506 HydrophobicContact CE-CB 4.09Å; M297-N506 WeakPolarHBondContact CE-ND2 3.16Å; D301-N506 PolarHBondContact OD1-ND2 3.49Å; D301-N506 PolarHBondContact OD2-OD1 3.43Å; Y502-N506 WeakPolarHBondContact CE2-ND2 3.42Å; Y502-N506 PolarHBondContact O-N 2.93Å; Y502-N506 PolarHBondContact O-ND2 2.66Å; G503-N506 WeakPolarHBondContact O-CB 3.43Å; G503-N506 PolarHBondContact O-N 3.05Å; M504-N506 VanDerWaalsContact C-N 3.3Å; M504-N506 PolarHBondContact O-N 3.37Å; N506-Y508 VanDerWaalsContact C-N 3.33Å; N506-Y508 PolarHBondContact O-N 3.12Å; N506-T509 PolarHBondContact O-N 2.88Å; N506-L510 WeakPolarHBondContact O-CG 3.4Å; N506-L510 PolarHBondContact O-N 2.03Å
507V93.3Very high90.7Very high6 Ų614.8 Ų14.84%0.0368%0.078CC..Hα-helixtrans-60.2-42.4177163.70000111.8L29 L32 F36 G503 M504 T509 L510 C511L29-V507 HydrophobicContact CB-CG1 3.98Å; L29-V507 HydrophobicContact CD1-CG1 4.13Å; L29-V507 HydrophobicContact CD2-CG1 3.83Å; L29-V507 HydrophobicContact CG-CG1 4.17Å; L32-V507 HydrophobicContact CD2-CG2 3.78Å; L32-V507 HydrophobicContact CG-CG2 4.19Å; F36-V507 HydrophobicContact CE2-CG2 3.91Å; G503-V507 WeakPolarHBondContact O-CB 3.39Å; G503-V507 WeakPolarHBondContact O-CG2 3.35Å; G503-V507 PolarHBondContact O-N 2.74Å; M504-V507 PolarHBondContact O-N 2.82Å; V507-T509 PolarHBondContact O-N 3.12Å; V507-L510 PolarHBondContact O-N 2.87Å; V507-C511 WeakPolarHBondContact O-CB 3.35Å; V507-C511 PolarHBondContact O-N 2.85Å
508Y93.5Very high90Very high0 Ų012.9 Ų12.90%07%0.071CC..Hα-helixtrans-58.7-48.2177.6-179.9-93.2000111.2L331 W335 L455 F458 T459 M504 W505 N506 C511 L512L331-Y508 HydrophobicContact CD1-CE1 4Å; W335-Y508 PolarHBondContact NE1-OH 2.9Å; W335-Y508 VanDerWaalsContact NE1-OH 3.07Å; L455-Y508 HydrophobicContact CD1-CE2 4.12Å; F458-Y508 AromaticContact CD1-CD2 3.62Å; F458-Y508 HydrophobicContact CD1-CD2 3.62Å; F458-Y508 AromaticContact CD1-CE2 3.8Å; F458-Y508 HydrophobicContact CD1-CE2 3.8Å; F458-Y508 AromaticContact CE1-CD2 3.32Å; F458-Y508 HydrophobicContact CE1-CD2 3.32Å; F458-Y508 AromaticContact CE1-CE2 3.98Å; F458-Y508 HydrophobicContact CE1-CE2 3.98Å; F458-Y508 HydrophobicContact CE1-CG 4.1Å; F458-Y508 HydrophobicContact CG-CD2 4.42Å; F458-Y508 AromaticContact CZ-CD2 3.9Å; F458-Y508 HydrophobicContact CZ-CD2 3.9Å; T459-Y508 PolarHBondContact OG1-OH 2.76Å; M504-Y508 VanDerWaalsContact O-CB 3.24Å; M504-Y508 WeakPolarHBondContact O-CB 3.13Å; M504-Y508 PolarHBondContact O-N 3.48Å; W505-Y508 AromaticContact CE3-CD1 3.94Å; W505-Y508 HydrophobicContact CE3-CD1 3.94Å; W505-Y508 HydrophobicContact CE3-CG 4.18Å; W505-Y508 AromaticContact CZ3-CD1 3.93Å; W505-Y508 HydrophobicContact CZ3-CD1 3.93Å; W505-Y508 HydrophobicContact CZ3-CE1 4.08Å; W505-Y508 HydrophobicContact CZ3-CG 4.24Å; N506-Y508 VanDerWaalsContact C-N 3.33Å; N506-Y508 PolarHBondContact O-N 3.12Å; Y508-C511 WeakPolarHBondContact O-CB 3.33Å; Y508-C511 PolarHBondContact O-N 3.11Å; Y508-L512 HydrophobicContact CD1-CD1 3.82Å; Y508-L512 HydrophobicContact CD1-CG 4.48Å; Y508-L512 HydrophobicContact CE1-CD1 3.29Å; Y508-L512 HydrophobicContact CE1-CG 4.2Å; Y508-L512 WeakPolarHBondContact O-CB 3.47Å; Y508-L512 WeakPolarHBondContact O-CG 3.36Å; Y508-L512 PolarHBondContact O-N 3.27Å
509T93.7Very high89.2Confident1 Ų110.3 Ų10.31%0.0066%0.059CC..Hα-helixtrans-67-44.1179.7-55.60000111.7M265 L293 M297 W505 N506 V507 C511 L512 L513M265-T509 HydrophobicContact CE-CG2 4.37Å; M265-T509 HydrophobicContact SD-CG2 4.1Å; L293-T509 HydrophobicContact CG-CG2 4.31Å; M297-T509 HydrophobicContact CB-CG2 4.01Å; M297-T509 HydrophobicContact CG-CG2 4.29Å; W505-T509 WeakPolarHBondContact O-CB 3.28Å; W505-T509 PolarHBondContact O-N 2.89Å; W505-T509 PolarHBondContact O-OG1 2.83Å; N506-T509 PolarHBondContact O-N 2.88Å; V507-T509 PolarHBondContact O-N 3.12Å; T509-C511 VanDerWaalsContact C-N 3.33Å; T509-C511 PolarHBondContact O-N 2.95Å; T509-L512 WeakPolarHBondContact O-CB 3.41Å; T509-L512 PolarHBondContact O-N 2.8Å; T509-L513 HydrophobicContact CG2-CD1 4.28Å; T509-L513 WeakPolarHBondContact O-CG 3.21Å; T509-L513 PolarHBondContact O-N 3.05Å
510L92.7Very high87.6Confident35 Ų3517.1 Ų17.118%0.1839%0.09CC..Hα-helixtrans-59.8-43.5174.5-72.6172.8000111.9I264 M265 A268 N506 V507 L513 A514I264-L510 HydrophobicContact CG2-CD1 4.04Å; I264-L510 HydrophobicContact CG2-CD2 4.39Å; M265-L510 HydrophobicContact CE-CD1 4.38Å; M265-L510 HydrophobicContact CE-CD2 3.92Å; M265-L510 HydrophobicContact CE-CG 3.68Å; M265-L510 HydrophobicContact SD-CD2 3.83Å; M265-L510 HydrophobicContact SD-CG 4.22Å; A268-L510 HydrophobicContact CB-CD2 3.39Å; N506-L510 WeakPolarHBondContact O-CG 3.4Å; N506-L510 PolarHBondContact O-N 2.03Å; V507-L510 PolarHBondContact O-N 2.87Å; L510-L513 PolarHBondContact O-N 3.4Å; L510-A514 VanDerWaalsContact O-CB 3.31Å; L510-A514 WeakPolarHBondContact O-CB 3.42Å; L510-A514 PolarHBondContact O-N 3.05Å
511C89.5Confident85.7Confident5 Ų523.2 Ų23.23%0.03412%0.117CC..Hα-helixtrans-60.4-47177.2-172.40000110.6L29 F458 V507 Y508 T509 A514 M515L29-C511 HydrophobicContact CD1-CB 3.98Å; F458-C511 HydrophobicContact CE1-CB 4.06Å; V507-C511 WeakPolarHBondContact O-CB 3.35Å; V507-C511 PolarHBondContact O-N 2.85Å; Y508-C511 WeakPolarHBondContact O-CB 3.33Å; Y508-C511 PolarHBondContact O-N 3.11Å; T509-C511 VanDerWaalsContact C-N 3.33Å; T509-C511 PolarHBondContact O-N 2.95Å; C511-A514 PolarHBondContact O-N 2.78Å; C511-M515 WeakPolarHBondContact O-CB 3.48Å; C511-M515 VanDerWaalsContact O-CG 3.3Å; C511-M515 WeakPolarHBondContact O-CG 3.48Å; C511-M515 PolarHBondContact O-N 3.35Å; C511-M515 PolarHBondContact SG-SD 3.31Å
512L90.5Very high83.5Confident4 Ų430 Ų302%0.02114%0.144CC..Hα-helixtrans-59.5-49.7176.3-83.2-178.7000112.7L290 L293 F334 L455 Y508 T509 A514 M515 Y516L290-L512 HydrophobicContact CD2-CB 3.87Å; L290-L512 HydrophobicContact CD2-CD1 4.09Å; L290-L512 HydrophobicContact CD2-CD2 4.32Å; L290-L512 HydrophobicContact CD2-CG 4.35Å; L293-L512 HydrophobicContact CD2-CD1 3.79Å; F334-L512 HydrophobicContact CD1-CD1 4.49Å; F334-L512 HydrophobicContact CE1-CD1 3.62Å; F334-L512 HydrophobicContact CZ-CD1 3.7Å; F334-L512 HydrophobicContact CZ-CD2 4.01Å; L455-L512 HydrophobicContact CD1-CD2 3.41Å; L455-L512 VanDerWaalsContact CD1-CD2 3.41Å; L455-L512 HydrophobicContact CD1-CG 4.21Å; L455-L512 HydrophobicContact CD2-CD2 3.78Å; L455-L512 HydrophobicContact CG-CD2 4.24Å; Y508-L512 HydrophobicContact CD1-CD1 3.82Å; Y508-L512 HydrophobicContact CD1-CG 4.48Å; Y508-L512 HydrophobicContact CE1-CD1 3.29Å; Y508-L512 HydrophobicContact CE1-CG 4.2Å; Y508-L512 WeakPolarHBondContact O-CB 3.47Å; Y508-L512 WeakPolarHBondContact O-CG 3.36Å; Y508-L512 PolarHBondContact O-N 3.27Å; T509-L512 WeakPolarHBondContact O-CB 3.41Å; T509-L512 PolarHBondContact O-N 2.8Å; L512-A514 VanDerWaalsContact C-N 3.34Å; L512-A514 PolarHBondContact O-N 3.16Å; L512-M515 PolarHBondContact O-N 2.71Å; L512-Y516 HydrophobicContact CD2-CD2 3.86Å; L512-Y516 HydrophobicContact CD2-CE2 3.74Å; L512-Y516 WeakPolarHBondContact O-CB 3.48Å; L512-Y516 WeakPolarHBondContact O-CD2 3.48Å; L512-Y516 PolarHBondContact O-N 2.71Å
513L91.1Very high81.1Confident1 Ų133.9 Ų33.91%0.00516%0.159CC..Hα-helixtrans-59.5-44.1177.7-69.4173.4000111.4M265 A268 V269 Y272 T509 L510 A517M265-L513 HydrophobicContact SD-CD1 4.27Å; A268-L513 HydrophobicContact CB-CD1 4.24Å; V269-L513 HydrophobicContact CG2-CD1 3.95Å; Y272-L513 HydrophobicContact CD1-CD2 3.82Å; Y272-L513 HydrophobicContact CD2-CB 4.45Å; Y272-L513 HydrophobicContact CD2-CD2 4.13Å; Y272-L513 WeakPolarHBondContact CD2-O 3.31Å; Y272-L513 HydrophobicContact CE1-CD2 4.2Å; Y272-L513 HydrophobicContact CE2-CD2 4.5Å; Y272-L513 HydrophobicContact CG-CD2 3.79Å; T509-L513 HydrophobicContact CG2-CD1 4.28Å; T509-L513 WeakPolarHBondContact O-CG 3.21Å; T509-L513 PolarHBondContact O-N 3.05Å; L510-L513 PolarHBondContact O-N 3.4Å; L513-A517 WeakPolarHBondContact O-CB 3.2Å; L513-A517 PolarHBondContact O-N 3.07Å; L513-A517 VanDerWaalsContact O-N 3.16Å
514A86.3Confident78.1Confident37 Ų3738.1 Ų38.131%0.30619%0.189SC..Hα-helixtrans-68.7-43.9179.800000112.9L510 C511 L512L510-A514 VanDerWaalsContact O-CB 3.31Å; L510-A514 WeakPolarHBondContact O-CB 3.42Å; L510-A514 PolarHBondContact O-N 3.05Å; C511-A514 PolarHBondContact O-N 2.78Å; L512-A514 VanDerWaalsContact C-N 3.34Å; L512-A514 PolarHBondContact O-N 3.16Å
515M82.5Confident75.2Confident6 Ų645.3 Ų45.33%0.0323%0.228CC..Hα-helixtrans-72.5-39.9-176.3-79.1-17482.800112.5S12 V14 F26 F454 C511 L512S12-M515 PolarHBondContact OG-O 3.5Å; V14-M515 HydrophobicContact CB-CE 4.43Å; V14-M515 HydrophobicContact CG1-CE 4.17Å; V14-M515 HydrophobicContact CG2-CB 3.33Å; V14-M515 HydrophobicContact CG2-CE 3.32Å; V14-M515 HydrophobicContact CG2-CG 3.59Å; V14-M515 VanDerWaalsContact CG2-O 3.26Å; V14-M515 WeakPolarHBondContact CG2-O 3.45Å; V14-M515 HydrophobicContact CG2-SD 4.24Å; V14-M515 PolarHBondContact N-O 3.36Å; F26-M515 HydrophobicContact CZ-CE 4.39Å; F454-M515 HydrophobicContact CD1-CE 3.36Å; F454-M515 HydrophobicContact CD1-SD 4Å; F454-M515 HydrophobicContact CE1-CE 3.32Å; F454-M515 HydrophobicContact CE1-SD 3.35Å; F454-M515 WeakPolarHBondContact CE1-SD 3.35Å; F454-M515 HydrophobicContact CG-CE 4.09Å; F454-M515 HydrophobicContact CZ-CE 4.04Å; F454-M515 HydrophobicContact CZ-SD 3.99Å; C511-M515 WeakPolarHBondContact O-CB 3.48Å; C511-M515 VanDerWaalsContact O-CG 3.3Å; C511-M515 WeakPolarHBondContact O-CG 3.48Å; C511-M515 PolarHBondContact O-N 3.35Å; C511-M515 PolarHBondContact SG-SD 3.31Å; L512-M515 PolarHBondContact O-N 2.71Å
516Y83.9Confident72.1Confident19 Ų1948.7 Ų48.78%0.07525%0.254CS..Hα-helixtrans-92.95-178.4-71.6-96.4000113.4L286 L290 F338 L455 L512L286-Y516 HydrophobicContact CD2-CD1 4.17Å; L286-Y516 HydrophobicContact CD2-CE1 4.24Å; L290-Y516 HydrophobicContact CD1-CD1 4.33Å; L290-Y516 HydrophobicContact CD1-CG 3.85Å; F338-Y516 AromaticContact CE2-CE1 3.85Å; F338-Y516 HydrophobicContact CE2-CE1 3.85Å; F338-Y516 AromaticContact CE2-CZ 3.68Å; F338-Y516 WeakPolarHBondContact CE2-OH 3.18Å; F338-Y516 VanDerWaalsContact CZ-OH 3.31Å; F338-Y516 WeakPolarHBondContact CZ-OH 3.32Å; L455-Y516 HydrophobicContact CD2-CE2 4.46Å; L512-Y516 HydrophobicContact CD2-CD2 3.86Å; L512-Y516 HydrophobicContact CD2-CE2 3.74Å; L512-Y516 WeakPolarHBondContact O-CB 3.48Å; L512-Y516 WeakPolarHBondContact O-CD2 3.48Å; L512-Y516 PolarHBondContact O-N 2.71Å
517A83.3Confident69Low0 Ų054.3 Ų54.30%029%0.294CS..SBendtrans-63.9140169.500000111.7S12 I13 W271 Y272 L513 S519S12-A517 WeakPolarHBondContact CA-O 3.43Å; S12-A517 WeakPolarHBondContact CB-O 3.47Å; I13-A517 HydrophobicContact CD1-CB 3.9Å; I13-A517 HydrophobicContact CG1-CB 4.43Å; I13-A517 PolarHBondContact N-O 3.14Å; W271-A517 HydrophobicContact CH2-CB 3.29Å; W271-A517 HydrophobicContact CZ2-CB 4.26Å; W271-A517 HydrophobicContact CZ3-CB 3.52Å; Y272-A517 HydrophobicContact CD2-CB 4.03Å; Y272-A517 HydrophobicContact CE2-CB 4.24Å; L513-A517 WeakPolarHBondContact O-CB 3.2Å; L513-A517 PolarHBondContact O-N 3.07Å; L513-A517 VanDerWaalsContact O-N 3.16Å; A517-S519 PolarHBondContact O-N 3.47Å
518P74.6Confident66Low9 Ų961.6 Ų61.66%0.05833%0.332CS..BIsolated β-bridgetrans-58.8133.1171.9-21.630.2000111.9R275 L276 L279R275-P518 WeakPolarHBondContact CD-O 3.42Å; R275-P518 PolarHBondContact NH1-O 3.13Å; L276-P518 HydrophobicContact CD2-CG 4.06Å; L279-P518 HydrophobicContact CD1-CB 3.99Å; L279-P518 HydrophobicContact CD1-CG 3.57Å; L279-P518 HydrophobicContact CD2-CB 3.97Å; L279-P518 HydrophobicContact CD2-CG 4.45Å; L279-P518 HydrophobicContact CG-CB 4.3Å; L279-P518 HydrophobicContact CG-CG 4.24Å
519S69.6Low62.9Low16 Ų1664.9 Ų64.911%0.11237%0.366CS..PPolyproline II helixtrans-86.4147176.1-174.20000111.5G11 N16 A517 K521G11-S519 WeakPolarHBondContact O-CA 3.35Å; G11-S519 WeakPolarHBondContact O-CB 3.14Å; G11-S519 PolarHBondContact O-N 3.11Å; N16-S519 VanDerWaalsContact ND2-CB 3.32Å; N16-S519 WeakPolarHBondContact ND2-CB 3.4Å; N16-S519 PolarHBondContact ND2-OG 3.31Å; A517-S519 PolarHBondContact O-N 3.47Å; S519-K521 PolarHBondContact O-N 3.22Å; S519-K521 PolarHBondContact OG-N 3.34Å
520H58.2Low59.8Low142 Ų14274.2 Ų74.266%0.65741%0.406SS*.SBendtrans-76.5-10.1171.1-69.1-70.7000113.4R275 K522R275-H520 PolarHBondContact NE-NE2 2.62Å; R275-H520 PolarHBondContact NH1-CD2 2.91Å; R275-H520 PolarHBondContact NH2-CD2 3.29Å; R275-H520 VanDerWaalsContact NH2-CD2 3.26Å; R275-H520 PolarHBondContact NH2-NE2 2.96Å; H520-K522 PolarHBondContact O-N 2.83Å
521K53.5Low56.8Low128 Ų12878.5 Ų78.556%0.55744%0.437SS*.  trans-78.2107.1178.7-69-173.3178.1-1750109.8N16 S519N16-K521 HydrophobicContact CB-CD 4.27Å; S519-K521 PolarHBondContact O-N 3.22Å; S519-K521 PolarHBondContact OG-N 3.34Å
522K46.7Very low54Low171 Ų17187 Ų8774%0.74347%0.473SS*.  trans-65.7142163.8-64.2-178.5179.7-179.70108.3H520 S524H520-K522 PolarHBondContact O-N 2.83Å; K522-S524 PolarHBondContact O-N 3Å
523Y42.3Very low51Low101 Ų10198.9 Ų98.940%0.39652%0.518SS..  trans-54.8113.5163.7-81.3-89000106.6E15 D525E15-Y523 PolarHBondContact OE2-OH 3.34Å; Y523-D525 PolarHBondContact O-N 2.93Å
524S31.5Very low48.3Very low89 Ų89105.3 Ų105.362%0.62255%0.55SS**  trans-62.9121.3173.751.70000107.2K522 S526K522-S524 PolarHBondContact O-N 3Å; S524-S526 VanDerWaalsContact C-N 3.26Å; S524-S526 PolarHBondContact O-N 2.79Å; S524-S526 PolarHBondContact O-OG 3.49Å
525D33.5Very low45.6Very low157 Ų157108.3 Ų108.384%0.8457%0.569SS**  trans-44.996.1163-87.8-38.4000108.9Y523Y523-D525 PolarHBondContact O-N 2.93Å
526S28.6Very low43.3Very low94 Ų94115.4 Ų115.466%0.65761%0.607SS**  trans-133.261.8177.943.40000105.9S524S524-S526 VanDerWaalsContact C-N 3.26Å; S524-S526 PolarHBondContact O-N 2.79Å; S524-S526 PolarHBondContact O-OG 3.49Å
527S30.7Very low40.9Very low119 Ų119123.7 Ų123.783%0.83265%0.647SS**SBendtrans175.6-3.815340.50000116.4G529S527-G529 PolarHBondContact O-N 3.36Å
528L29.9Very low38.5Very low159 Ų159127 Ų12783%0.83268%0.681SS**SBendtrans-82.1107.3164.9-107.878.1000109.4K530L528-K530 PolarHBondContact O-N 2.74Å
529G28.2Very low36.6Very low70 Ų70135.7 Ų135.772%0.72272%0.721SS**  trans-50.8126.1-179.400000111.6S527S527-G529 PolarHBondContact O-N 3.36Å
530K28.4Very low34.8Very low196 Ų196143.6 Ų143.685%0.85276%0.756SS**  trans-49128.9159.8-72.8179.8175.5-179.40107.7L528 K532L528-K530 PolarHBondContact O-N 2.74Å; K530-K532 PolarHBondContact O-N 3.1Å
531P30.3Very low33.7Very low126 Ų126144.9 Ų144.982%0.81877%0.768SS**  trans-66.2110.5170.827.7-29.2000106.4R533P531-R533 PolarHBondContact O-N 3.44Å
532K30.4Very low32.5Very low184 Ų184142.5 Ų142.580%0.878%0.779SS**  trans-60.5108.6161-92.8-177.1173.5-179.70105.5K530 I534K530-K532 PolarHBondContact O-N 3.1Å; K532-I534 VanDerWaalsContact C-N 3.31Å; K532-I534 HydrophobicContact CB-CG1 4.47Å; K532-I534 PolarHBondContact O-N 3.21Å
533R28.4Very low31.9Very low253 Ų253143 Ų14396%0.95579%0.785SS**  trans-53.5101158.3-87-177.2175.5177.9-2.4107.2P531P531-R533 PolarHBondContact O-N 3.44Å
534I33.6Very low31.3Very low135 Ų135148.1 Ų148.169%0.69281%0.812SS**  trans-123.9109.5158.4-64.7177.2000104.3K532 N536K532-I534 VanDerWaalsContact C-N 3.31Å; K532-I534 HydrophobicContact CB-CG1 4.47Å; K532-I534 PolarHBondContact O-N 3.21Å; I534-N536 PolarHBondContact O-N 3.23Å
535S29.8Very low31.4Very low101 Ų101153 Ų15371%0.70683%0.825SS**  trans-36.2121.6160.743.70000112.1
536N34.9Very low31.3Very low154 Ų154152 Ų15282%0.82482%0.82SS**  -166.3146.4125-97.7-0.8000110.4I534I534-N536 PolarHBondContact O-N 3.23Å
537E32.9Very low31.3Very low193 Ų193154 Ų15490%0.90282%0.819SS**  trans-56.5149.3-175.1-62.2153158.900113.2
538G33.3Very low31.3Very low70 Ų70151.5 Ų151.572%0.72280%0.801SS**  trans144.591.8164.200000115
539E34.1Very low31.3Very low192 Ų192151.5 Ų151.590%0.89779%0.791SS**  trans60.6111.8142.4-73168.7156.400121.5
540E32Very low31.6Very low181 Ų181154.2 Ų154.285%0.84679%0.793SS**  trans6.3120.3137-62.3177164.100118
541D34.5Very low31.9Very low169 Ų169150 Ų15090%0.90479%0.789SS**  -166.5128.1123.1-89.3-29.2000109.6
542G28Very low32.3Very low78 Ų78147.9 Ų147.980%0.80477%0.774SS**  trans-95.4125.3-177.100000111.8
543E34.9Very low32.4Very low183 Ų183144.6 Ų144.686%0.85576%0.761SS**  trans-133.2120.1162-74.9-172.2155.700110E545E543-E545 PolarHBondContact O-N 2.98Å
544E29.3Very low32.9Very low208 Ų208137.5 Ų137.597%0.97274%0.74SS**  trans-72.6101.2171.4-70.6-179.8139.400109.2
545E33.9Very low33.1Very low191 Ų191134.1 Ų134.189%0.89373%0.729SS**  trans-87.8129.8173.7-95.7-169.816100113.5E543E543-E545 PolarHBondContact O-N 2.98Å
546D31.7Very low33.3Very low137 Ų137132.1 Ų132.173%0.73372%0.718SS**  trans-64.2137.2-168.8-118.3-30.9000115.6S548D546-S548 VanDerWaalsContact C-N 3.3Å; D546-S548 PolarHBondContact O-N 3.42Å; D546-S548 VanDerWaalsContact O-N 3.15Å
547Q28.9Very low33.4Very low136 Ų136128.6 Ų128.664%0.63670%0.698SS**THydrogen-bonded Turntrans-8529.6-174.2-118.1172.826.200114.7
548S29.9Very low33.8Very low66 Ų66122.3 Ų122.346%0.46267%0.673SS.*THydrogen-bonded Turntrans-104.50.3-170.468.20000116.1D546 V550D546-S548 VanDerWaalsContact C-N 3.3Å; D546-S548 PolarHBondContact O-N 3.42Å; D546-S548 VanDerWaalsContact O-N 3.15Å; S548-V550 PolarHBondContact O-N 3Å
549Y30.6Very low34Very low159 Ų159122.8 Ų122.862%0.62467%0.67SS**THydrogen-bonded Turntrans-82.6-8.2-164.3-97.7-94.1000118E553Y549-E553 WeakPolarHBondContact O-CG 3.4Å
550V34.9Very low34.2Very low126 Ų126120.6 Ų120.676%0.76466%0.664SS**THydrogen-bonded Turntrans-93.9-13.4-170-175.60000113.8S548S548-V550 PolarHBondContact O-N 3Å
551S34.4Very low34.7Very low109 Ų109115.5 Ų115.576%0.76265%0.653SS**SBendtrans-99.4-1.9-179.749.70000115
552T37.2Very low34.6Very low81 Ų81115.6 Ų115.650%0.49765%0.646SS.*SBendtrans-124.5-8.7-166.6-30.80000113.9M554 S555T552-M554 PolarHBondContact O-N 3.5Å; T552-S555 PolarHBondContact O-N 3.48Å
553E32.9Very low35Very low115 Ų115116.5 Ų116.554%0.53764%0.637SS.*THydrogen-bonded Turntrans-80.6-13.6-168.7-84.4-168.4161.100116.5Y549 L557Y549-E553 WeakPolarHBondContact O-CG 3.4Å; E553-L557 WeakPolarHBondContact O-CD1 3.39Å
554M39.2Very low34.8Very low103 Ų103112.3 Ų112.351%0.50763%0.634SS.*THydrogen-bonded Turntrans-86.5-19.2170.2-82-167.8-81.900112.1E346 T552 T558E346-M554 HydrophobicContact CG-CB 4.21Å; E346-M554 WeakPolarHBondContact OE1-CB 3.4Å; E346-M554 WeakPolarHBondContact OE2-CB 3.37Å; T552-M554 PolarHBondContact O-N 3.5Å; M554-T558 PolarHBondContact O-OG1 3.03Å
555S37.3Very low35.1Very low65 Ų65111.1 Ų111.146%0.45563%0.626SS.*Hα-helixtrans-80.5-31.9-179.5-660000112E346 T552 L557E346-S555 WeakPolarHBondContact OE2-CA 3.19Å; E346-S555 WeakPolarHBondContact OE2-CB 3.15Å; E346-S555 PolarHBondContact OE2-N 3.2Å; E346-S555 PolarHBondContact OE2-OG 2.86Å; T552-S555 PolarHBondContact O-N 3.48Å; S555-L557 VanDerWaalsContact C-N 3.29Å; S555-L557 PolarHBondContact O-N 2.95Å
556A34.2Very low34.9Very low58 Ų58113.2 Ų113.248%0.47964%0.643SS.*Hα-helixtrans-70.4-22.5175.600000113.6
557L36.6Very low35.1Very low80 Ų80112.1 Ų112.142%0.41964%0.639SS.*Hα-helixtrans-93.5-17.7-173.7-77.1164.1000114.2E553 S555 A561E553-L557 WeakPolarHBondContact O-CD1 3.39Å; S555-L557 VanDerWaalsContact C-N 3.29Å; S555-L557 PolarHBondContact O-N 2.95Å; L557-A561 PolarHBondContact O-N 3.05Å
558T42.3Very low35.4Very low61 Ų61110.8 Ų110.837%0.37464%0.639SS.*Hα-helixtrans-81.5-28171.1-43.90000110.8M554 L560 A561M554-T558 PolarHBondContact O-OG1 3.03Å; T558-L560 VanDerWaalsContact C-N 3.31Å; T558-L560 PolarHBondContact O-N 3.27Å; T558-A561 PolarHBondContact O-N 3.1Å
559A37.9Very low35.7Very low80 Ų80113.3 Ų113.366%0.66165%0.649SS**Hα-helixtrans-68.2-28170.500000113.1
560L38.5Very low36Very low147 Ų147110.6 Ų110.677%0.7765%0.65SS**THydrogen-bonded Turntrans-88.5-9.4178.9-98.8154.6000114.5T558T558-L560 VanDerWaalsContact C-N 3.31Å; T558-L560 PolarHBondContact O-N 3.27Å
561A40.7Very low36Very low74 Ų74109.6 Ų109.661%0.61264%0.643SS**SBendtrans-103.25.218000000113.7L557 T558 P563L557-A561 PolarHBondContact O-N 3.05Å; T558-A561 PolarHBondContact O-N 3.1Å; A561-P563 WeakPolarHBondContact O-CD 3.4Å
562K32.9Very low36.2Very low171 Ų171109.7 Ų109.774%0.74364%0.635SS**  trans-81.9107.7171.6-159.9178.5-175.9-172.40108.3A564K562-A564 PolarHBondContact O-N 3.03Å
563P37Very low36.1Very low96 Ų96111.7 Ų111.762%0.62365%0.645SS**  trans-63.7127.3163.627.8-30.6000107.1A561 F565A561-P563 WeakPolarHBondContact O-CD 3.4Å; P563-F565 HydrophobicContact CB-CD2 4.44Å; P563-F565 PolarHBondContact O-N 3.42Å
564A29.8Very low36.3Very low96 Ų96111.5 Ų111.579%0.79365%0.654SS**  trans-61.2100.6168.100000108.7K562K562-A564 PolarHBondContact O-N 3.03Å
565F35.6Very low36.1Very low183 Ų183112.2 Ų112.280%0.80367%0.666SS**  trans-140.9103.3155.1-79.3-76.2000104.8P563P563-F565 HydrophobicContact CB-CD2 4.44Å; P563-F565 PolarHBondContact O-N 3.42Å
566D30.3Very low36Very low235 Ų235116.5 Ų116.5100%1.25769%0.685SS**  trans27.80168.9-58.3-24.4000119.9

Retrieved 566 of 566 residues in 171.3 ms (Link to these results)