A0A078BQP7_CAEEL Loading...

Purple acid phosphatase

AlphaFold DB , UniProt , Accession A0A078BQP7, Species CAEEL (Caenorhabditis elegans), Gene n/a, Length 364 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M94.4Very high95.7Very high98 Ų9883 Ų8348%0.48340%0.395SS..  0149.80-68.3161.345.200108.6L9 W11 T12 Y48 K49M1-L9 HydrophobicContact CB-CB 3.94Å; M1-L9 HydrophobicContact CB-CD1 4.27Å; M1-L9 HydrophobicContact CE-CB 3.83Å; M1-L9 HydrophobicContact CE-CD1 4.44Å; M1-W11 CarbonylContact C-O 3.57Å; M1-W11 WeakPolarHBondContact CA-O 3.41Å; M1-T12 HydrophobicContact CG-CG2 4.04Å; M1-Y48 VanDerWaalsContact O-CA 3.28Å; M1-Y48 WeakPolarHBondContact O-CA 3.14Å; M1-Y48 WeakPolarHBondContact O-CB 3.39Å; M1-K49 PolarHBondContact N-O 2.87Å; M1-K49 PolarHBondContact O-N 2.76Å
2Y97.3Very high95.7Very high24 Ų2485.4 Ų85.49%0.09442%0.42CS..EExtended strand (participates in β ladder)trans-151.1162.5178.966-77000112.4L9 R10 W11 A13 M37 Y46 Y47Y2-L9 CarbonylContact O-C 3.59Å; Y2-L9 VanDerWaalsContact O-C 3.25Å; Y2-L9 WeakPolarHBondContact O-CA 3.35Å; Y2-R10 PolarHBondContact O-N 2.73Å; Y2-W11 HydrophobicContact CD1-CB 3.96Å; Y2-W11 HydrophobicContact CD2-CB 4.12Å; Y2-W11 AromaticContact CD2-CE3 3.71Å; Y2-W11 HydrophobicContact CD2-CE3 3.71Å; Y2-W11 HydrophobicContact CE1-CB 3.59Å; Y2-W11 HydrophobicContact CE2-CB 3.76Å; Y2-W11 HydrophobicContact CE2-CD2 4.17Å; Y2-W11 AromaticContact CE2-CE3 3.68Å; Y2-W11 HydrophobicContact CE2-CE3 3.68Å; Y2-W11 HydrophobicContact CE2-CG 4.25Å; Y2-W11 HydrophobicContact CG-CB 4.2Å; Y2-W11 VanDerWaalsContact CZ-CB 3.48Å; Y2-W11 PolarHBondContact N-O 2.76Å; Y2-W11 PolarHBondContact O-N 3.17Å; Y2-A13 HydrophobicContact CE1-CB 4.11Å; Y2-M37 HydrophobicContact CD1-CG 3.96Å; Y2-M37 HydrophobicContact CD1-SD 4.06Å; Y2-M37 HydrophobicContact CD2-CG 4.24Å; Y2-M37 HydrophobicContact CD2-SD 3.79Å; Y2-M37 HydrophobicContact CE1-CB 4.49Å; Y2-M37 HydrophobicContact CE1-CG 4.05Å; Y2-M37 HydrophobicContact CE2-CB 4.26Å; Y2-M37 HydrophobicContact CE2-CG 4.33Å; Y2-M37 HydrophobicContact CE2-SD 4.41Å; Y2-M37 HydrophobicContact CG-CE 4.27Å; Y2-M37 HydrophobicContact CG-CG 4.07Å; Y2-M37 HydrophobicContact CG-SD 3.61Å; Y2-Y46 HydrophobicContact CD2-CD1 4.22Å; Y2-Y47 CarbonylContact C-O 3.5Å; Y2-Y47 WeakPolarHBondContact CA-O 3.33Å; Y2-Y47 WeakPolarHBondContact CB-O 3.43Å
3G97.1Very high95.8Very high1 Ų181.2 Ų81.21%0.0141%0.406CS..EExtended strand (participates in β ladder)trans-173.3173.5-177.100000113.1S5 Y46 Y47G3-S5 VanDerWaalsContact C-N 3.28Å; G3-Y46 WeakPolarHBondContact O-CA 3.28Å; G3-Y47 PolarHBondContact N-O 3.47Å; G3-Y47 PolarHBondContact O-N 3.43Å
4L96.7Very high95.8Very high84 Ų8489.6 Ų89.644%0.4444%0.439SS..SBendtrans-82.9-2.4177.5-65.2173.4000113.7W11 D44 Y46L4-W11 HydrophobicContact CD1-CH2 4Å; L4-W11 HydrophobicContact CG-CH2 3.82Å; L4-W11 HydrophobicContact CG-CZ3 3.94Å; L4-D44 HydrophobicContact CD2-CB 3.85Å; L4-Y46 HydrophobicContact CD2-CD1 3.98Å; L4-Y46 HydrophobicContact CD2-CE1 3.62Å; L4-Y46 HydrophobicContact CD2-CE2 4.35Å; L4-Y46 HydrophobicContact CD2-CG 4.47Å; L4-Y46 HydrophobicContact CG-CE1 4.43Å
5S96.1Very high95.8Very high53 Ų5386.5 Ų86.537%0.37143%0.434SS..SBendtrans-141144.1176.8166.80000110.3G3 D7 A8G3-S5 VanDerWaalsContact C-N 3.28Å; S5-D7 PolarHBondContact O-N 3.21Å; S5-D7 PolarHBondContact OG-N 2.74Å; S5-A8 CarbonylContact O-C 3.58Å; S5-A8 PolarHBondContact O-N 3.27Å; S5-A8 VanDerWaalsContact O-N 3.07Å
6K95.3Very high95.8Very high120 Ų12086.9 Ų86.952%0.52244%0.443SS..THydrogen-bonded Turntrans-53.6-35178.1-168.7-178.3178.6176.30112.7Y47 V59K6-Y47 HydrophobicContact CB-CD1 3.72Å; K6-Y47 HydrophobicContact CB-CE1 3.95Å; K6-Y47 HydrophobicContact CB-CG 4.2Å; K6-Y47 HydrophobicContact CG-CD1 4.17Å; K6-V59 HydrophobicContact CG-CB 4.11Å; K6-V59 HydrophobicContact CG-CG1 3.87Å; K6-V59 HydrophobicContact CG-CG2 4.13Å
7D94.5Very high95.8Very high153 Ų15386.5 Ų86.582%0.81845%0.445SS*.THydrogen-bonded Turntrans-93.7-3-175.6-54.8-41.5000113S5S5-D7 PolarHBondContact O-N 3.21Å; S5-D7 PolarHBondContact OG-N 2.74Å
8A94.3Very high95.8Very high31 Ų3185 Ų8526%0.25644%0.441SS..  trans-138.469.3-173.700000112.4S5 R10S5-A8 CarbonylContact O-C 3.58Å; S5-A8 PolarHBondContact O-N 3.27Å; S5-A8 VanDerWaalsContact O-N 3.07Å; A8-R10 VanDerWaalsContact C-N 3.31Å; A8-R10 HydrophobicContact CB-CG 4.4Å; A8-R10 PolarHBondContact O-N 2.96Å
9L96Very high95.8Very high24 Ų2484.4 Ų84.413%0.12644%0.444CS..  trans-80.673175.3-52.1-174.4000111.5M1 Y2 W11 Y47 K49M1-L9 HydrophobicContact CB-CB 3.94Å; M1-L9 HydrophobicContact CB-CD1 4.27Å; M1-L9 HydrophobicContact CE-CB 3.83Å; M1-L9 HydrophobicContact CE-CD1 4.44Å; Y2-L9 CarbonylContact O-C 3.59Å; Y2-L9 VanDerWaalsContact O-C 3.25Å; Y2-L9 WeakPolarHBondContact O-CA 3.35Å; L9-W11 PolarHBondContact O-N 2.92Å; L9-Y47 WeakPolarHBondContact CD2-O 3.34Å; L9-K49 HydrophobicContact CD1-CB 3.98Å; L9-K49 HydrophobicContact CD1-CD 3.96Å; L9-K49 HydrophobicContact CD1-CG 3.75Å
10R95.3Very high95.7Very high212 Ų21281.1 Ų81.180%0.843%0.426SS*.  trans-78.6-13-169.3-64.4-177.8-179.8-1771.2115.2Y2 A8Y2-R10 PolarHBondContact O-N 2.73Å; A8-R10 VanDerWaalsContact C-N 3.31Å; A8-R10 HydrophobicContact CB-CG 4.4Å; A8-R10 PolarHBondContact O-N 2.96Å
11W96.3Very high95.5Very high113 Ų11383.7 Ų83.743%0.42843%0.434SS..BIsolated β-bridgetrans-111.6153.7-177.7-54.9-56.4000112.1M1 Y2 L4 L9 Y46M1-W11 CarbonylContact C-O 3.57Å; M1-W11 WeakPolarHBondContact CA-O 3.41Å; Y2-W11 HydrophobicContact CD1-CB 3.96Å; Y2-W11 HydrophobicContact CD2-CB 4.12Å; Y2-W11 AromaticContact CD2-CE3 3.71Å; Y2-W11 HydrophobicContact CD2-CE3 3.71Å; Y2-W11 HydrophobicContact CE1-CB 3.59Å; Y2-W11 HydrophobicContact CE2-CB 3.76Å; Y2-W11 HydrophobicContact CE2-CD2 4.17Å; Y2-W11 AromaticContact CE2-CE3 3.68Å; Y2-W11 HydrophobicContact CE2-CE3 3.68Å; Y2-W11 HydrophobicContact CE2-CG 4.25Å; Y2-W11 HydrophobicContact CG-CB 4.2Å; Y2-W11 VanDerWaalsContact CZ-CB 3.48Å; Y2-W11 PolarHBondContact N-O 2.76Å; Y2-W11 PolarHBondContact O-N 3.17Å; L4-W11 HydrophobicContact CD1-CH2 4Å; L4-W11 HydrophobicContact CG-CH2 3.82Å; L4-W11 HydrophobicContact CG-CZ3 3.94Å; L9-W11 PolarHBondContact O-N 2.92Å; W11-Y46 HydrophobicContact CZ3-CD1 4.18Å; W11-Y46 AromaticContact CZ3-CE1 3.79Å; W11-Y46 HydrophobicContact CZ3-CE1 3.79Å
12T95.3Very high95.1Very high112 Ų11279.1 Ų79.169%0.68741%0.411SS*.  trans-129.9132.8179.658.30000110.3M1M1-T12 HydrophobicContact CG-CG2 4.04Å
13A96.4Very high94.3Very high30 Ų3082.4 Ų82.425%0.24843%0.428CS..  trans-112.5128164.200000107.2Y2 A35 T36Y2-A13 HydrophobicContact CE1-CB 4.11Å; A13-A35 HydrophobicContact CB-CB 4.19Å; A13-T36 WeakPolarHBondContact CB-O 3.36Å
14K96.4Very high93.6Very high199 Ų19983.4 Ų83.487%0.86544%0.438SS*.PPolyproline II helixtrans-80.5128.9177.7-173.3174.9179.6-179.80108.9
15A96.1Very high93Very high44 Ų4484.6 Ų84.636%0.36445%0.453SS..PPolyproline II helixtrans-79146.8175.100000111.5H33 R34 A35A15-H33 HydrophobicContact CB-CB 4.33Å; A15-R34 CarbonylContact C-O 3.56Å; A15-R34 WeakPolarHBondContact CA-O 3.4Å; A15-A35 HydrophobicContact CB-CB 4.01Å
16T95.6Very high92.6Very high93 Ų9388.2 Ų88.257%0.57146%0.464SS*.EExtended strand (participates in β ladder)trans-92.5142.1158.257.60000109.2H33 R34T16-H33 CarbonylContact O-C 3.55Å; T16-H33 WeakPolarHBondContact O-CA 3.06Å; T16-R34 PolarHBondContact N-O 3.32Å; T16-R34 PolarHBondContact O-N 3.49Å; T16-R34 PolarHBondContact OG1-O 2.9Å
17T96.1Very high92.1Very high79 Ų7982.9 Ų82.949%0.48544%0.443SS..EExtended strand (participates in β ladder)trans-110.4126.1176.3-57.70000108.8Y31 T32 H33T17-Y31 HydrophobicContact CG2-CD1 3.9Å; T17-Y31 HydrophobicContact CG2-CG 4.5Å; T17-T32 WeakPolarHBondContact CA-O 3.21Å; T17-H33 PolarHBondContact OG1-CE1 2.87Å; T17-H33 PolarHBondContact OG1-ND1 2.74Å
18T95.1Very high92Very high60 Ų6081.1 Ų81.137%0.36843%0.426SS..EExtended strand (participates in β ladder)trans-112123171.1-56.30000108.3Y31 T32T18-Y31 WeakPolarHBondContact O-CA 3.23Å; T18-T32 PolarHBondContact N-O 3.46Å; T18-T32 PolarHBondContact O-N 2.78Å
19S95.8Very high91.9Very high73 Ų7383.6 Ų83.651%0.5144%0.438SS..EExtended strand (participates in β ladder)trans-86.4140.4166.659.70000110R30S19-R30 CarbonylContact C-O 3.47Å; S19-R30 VanDerWaalsContact CA-O 3.26Å; S19-R30 WeakPolarHBondContact CA-O 3.42Å
20W94.1Very high91.9Very high19 Ų1983.8 Ų83.87%0.07244%0.437CS..EExtended strand (participates in β ladder)trans-144149.9177.354.8-80.3000109.6V29 R30 T32 N151 N155 R156W20-V29 WeakPolarHBondContact O-CA 3.18Å; W20-R30 HydrophobicContact CD2-CB 4Å; W20-R30 VanDerWaalsContact CE2-CB 3.45Å; W20-R30 HydrophobicContact CH2-CB 4.07Å; W20-R30 HydrophobicContact CH2-CG 4.27Å; W20-R30 HydrophobicContact CZ2-CB 3.52Å; W20-R30 VanDerWaalsContact CZ2-CD 3.48Å; W20-R30 HydrophobicContact CZ2-CG 4.12Å; W20-R30 PolarHBondContact N-O 2.93Å; W20-R30 PolarHBondContact O-N 2.85Å; W20-T32 PolarHBondContact NE1-OG1 2.62Å; W20-N151 VanDerWaalsContact CE3-OD1 3.24Å; W20-N151 WeakPolarHBondContact CZ3-OD1 3.47Å; W20-N155 HydrophobicContact CB-CB 4.4Å; W20-N155 HydrophobicContact CD2-CB 3.47Å; W20-N155 VanDerWaalsContact CD2-CB 3.47Å; W20-N155 VanDerWaalsContact CE2-CB 3.49Å; W20-N155 HydrophobicContact CE3-CB 4.03Å; W20-N155 HydrophobicContact CG-CB 3.64Å; W20-N155 VanDerWaalsContact CG-CG 3.47Å; W20-N155 HydrophobicContact CZ2-CB 4.05Å; W20-R156 HydrophobicContact CH2-CG 4.41Å; W20-R156 HydrophobicContact CZ2-CG 4.14Å
21K90.9Very high91.9Very high135 Ų13580.9 Ų80.959%0.58743%0.427SS*.EExtended strand (participates in β ladder)trans-95.2129.6-179.9-163.9-172.6172.7-179.20108.8G27K21-G27 VanDerWaalsContact CE-O 3.31Å; K21-G27 WeakPolarHBondContact CE-O 2.98Å; K21-G27 WeakPolarHBondContact CG-O 3.49Å
22D85.8Confident91.8Very high3 Ų376.5 Ų76.52%0.01641%0.412CS..  trans-65.3149.9167.9-159.8-85.7000110.8G24 Y28 R30 G118 Q152D22-G24 VanDerWaalsContact C-N 3.29Å; D22-G24 PolarHBondContact O-N 3.05Å; D22-G24 PolarHBondContact OD1-N 3Å; D22-Y28 PolarHBondContact N-O 2.95Å; D22-R30 VanDerWaalsContact CG-NH1 3.26Å; D22-R30 IonicContact OD2-CZ 2.79Å; D22-R30 IonicContact OD2-NH1 3.45Å; D22-R30 PolarHBondContact OD2-NH1 2.88Å; D22-G118 WeakPolarHBondContact OD2-CA 3.48Å; D22-Q152 PolarHBondContact OD2-NE2 3.16Å
23Q81.8Confident91.9Very high93 Ų9377.1 Ų77.144%0.43541%0.407SS..SBendtrans-84.8-1.9-177.6-67.3-179.4-5.200113.2S148Q23-S148 VanDerWaalsContact CD-O 3.32Å; Q23-S148 PolarHBondContact NE2-O 3.1Å; Q23-S148 PolarHBondContact OE1-O 3.41Å; Q23-S148 VanDerWaalsContact OE1-O 3.12Å
24G80.9Confident91.9Very high22 Ų2277.7 Ų77.723%0.22740%0.403CS..SBendtrans-61.9163.5171.400000114.5D22 H26 G27D22-G24 VanDerWaalsContact C-N 3.29Å; D22-G24 PolarHBondContact O-N 3.05Å; D22-G24 PolarHBondContact OD1-N 3Å; G24-H26 PolarHBondContact O-N 3.31Å; G24-G27 WeakPolarHBondContact O-CA 3.39Å; G24-G27 PolarHBondContact O-N 2.82Å
25S84.7Confident91.8Very high109 Ų10971 Ų7176%0.76238%0.384SS*.THydrogen-bonded Turntrans-61.7-36.4-173.557.80000114.2G27S25-G27 VanDerWaalsContact C-N 3.33Å
26H88.6Confident91.8Very high129 Ų12974.1 Ų74.160%0.59740%0.399SS*.THydrogen-bonded Turntrans-77.2-22.3174.8-59.692.1000112.6G24 Y28 E117G24-H26 PolarHBondContact O-N 3.31Å; H26-Y28 HydrophobicContact CB-CE1 4.48Å; H26-Y28 HydrophobicContact CB-CE2 4.27Å; H26-E117 VanDerWaalsContact CB-OE2 3.3Å; H26-E117 WeakPolarHBondContact CB-OE2 3.35Å; H26-E117 IonicContact CE1-OE1 3.21Å; H26-E117 PolarHBondContact CE1-OE1 3.01Å; H26-E117 IonicContact CE1-OE2 3.92Å; H26-E117 IonicContact CG-OE1 3.31Å; H26-E117 IonicContact CG-OE2 3.11Å; H26-E117 IonicContact ND1-OE1 2.68Å; H26-E117 PolarHBondContact ND1-OE1 3.35Å; H26-E117 IonicContact ND1-OE2 2.8Å; H26-E117 PolarHBondContact ND1-OE2 3.41Å
27G83.9Confident91.7Very high8 Ų872 Ų728%0.08238%0.383CS..  trans66.345.2172.500000114.1K21 G24 S25K21-G27 VanDerWaalsContact CE-O 3.31Å; K21-G27 WeakPolarHBondContact CE-O 2.98Å; K21-G27 WeakPolarHBondContact CG-O 3.49Å; G24-G27 WeakPolarHBondContact O-CA 3.39Å; G24-G27 PolarHBondContact O-N 2.82Å; S25-G27 VanDerWaalsContact C-N 3.33Å
28Y91.6Very high91.5Very high116 Ų11672.2 Ų72.246%0.45539%0.385SS..  trans-52.1139.6177.7-67.4-59.7000112D22 H26 E117D22-Y28 PolarHBondContact N-O 2.95Å; H26-Y28 HydrophobicContact CB-CE1 4.48Å; H26-Y28 HydrophobicContact CB-CE2 4.27Å; Y28-E117 HydrophobicContact CD2-CB 3.97Å; Y28-E117 HydrophobicContact CE2-CB 4Å; Y28-E117 WeakPolarHBondContact CE2-OE2 2.97Å
29V94.2Very high91.2Very high83 Ų8378.9 Ų78.950%0.50341%0.409SS..EExtended strand (participates in β ladder)trans-94.6120172.9179.70000108.5W20 Y31W20-V29 WeakPolarHBondContact O-CA 3.18Å; V29-Y31 HydrophobicContact CG1-CE2 4.28Å
30R94.2Very high91.1Very high28 Ų2877.3 Ų77.311%0.10639%0.394CS..EExtended strand (participates in β ladder)trans-105.7156.5176.1-72.1180168.478.54.7110.4S19 W20 D22 E117 G118 N119 D122S19-R30 CarbonylContact C-O 3.47Å; S19-R30 VanDerWaalsContact CA-O 3.26Å; S19-R30 WeakPolarHBondContact CA-O 3.42Å; W20-R30 HydrophobicContact CD2-CB 4Å; W20-R30 VanDerWaalsContact CE2-CB 3.45Å; W20-R30 HydrophobicContact CH2-CB 4.07Å; W20-R30 HydrophobicContact CH2-CG 4.27Å; W20-R30 HydrophobicContact CZ2-CB 3.52Å; W20-R30 VanDerWaalsContact CZ2-CD 3.48Å; W20-R30 HydrophobicContact CZ2-CG 4.12Å; W20-R30 PolarHBondContact N-O 2.93Å; W20-R30 PolarHBondContact O-N 2.85Å; D22-R30 VanDerWaalsContact CG-NH1 3.26Å; D22-R30 IonicContact OD2-CZ 2.79Å; D22-R30 IonicContact OD2-NH1 3.45Å; D22-R30 PolarHBondContact OD2-NH1 2.88Å; R30-E117 PolarHBondContact NH1-O 3.19Å; R30-E117 PolarHBondContact NH2-O 2.85Å; R30-G118 VanDerWaalsContact NH2-C 3.35Å; R30-N119 PolarHBondContact NH2-OD1 3.03Å; R30-D122 IonicContact CZ-OD2 3Å; R30-D122 IonicContact NE-OD1 2.77Å; R30-D122 IonicContact NE-OD2 3.35Å; R30-D122 PolarHBondContact NE-OD2 2.84Å; R30-D122 VanDerWaalsContact NE-OD2 3.12Å; R30-D122 IonicContact NH2-OD2 3.35Å; R30-D122 PolarHBondContact NH2-OD2 2.78Å
31Y95Very high91.1Very high151 Ų15180 Ų8059%0.59241%0.412SS*.EExtended strand (participates in β ladder)trans-123125.6179.9-61.5-89.5000109.7T17 T18 V29T17-Y31 HydrophobicContact CG2-CD1 3.9Å; T17-Y31 HydrophobicContact CG2-CG 4.5Å; T18-Y31 WeakPolarHBondContact O-CA 3.23Å; V29-Y31 HydrophobicContact CG1-CE2 4.28Å
32T95.9Very high91.2Very high20 Ų2076.9 Ų76.912%0.12341%0.406CS..EExtended strand (participates in β ladder)trans-110130.8172.2-53.40000109.9T17 T18 W20 R34 N155T17-T32 WeakPolarHBondContact CA-O 3.21Å; T18-T32 PolarHBondContact N-O 3.46Å; T18-T32 PolarHBondContact O-N 2.78Å; W20-T32 PolarHBondContact NE1-OG1 2.62Å; T32-R34 HydrophobicContact CG2-CG 4.29Å; T32-N155 VanDerWaalsContact CB-O 3.26Å; T32-N155 WeakPolarHBondContact CB-O 3.41Å; T32-N155 WeakPolarHBondContact CG2-O 3.23Å; T32-N155 PolarHBondContact OG1-O 3.01Å
33H96.1Very high91.5Very high125 Ų12578.1 Ų78.158%0.57942%0.419SS*.EExtended strand (participates in β ladder)trans-106127.1177.5-52.7-75.6000110.2A15 T16 T17A15-H33 HydrophobicContact CB-CB 4.33Å; T16-H33 CarbonylContact O-C 3.55Å; T16-H33 WeakPolarHBondContact O-CA 3.06Å; T17-H33 PolarHBondContact OG1-CE1 2.87Å; T17-H33 PolarHBondContact OG1-ND1 2.74Å
34R96.3Very high92.1Very high42 Ų4276.4 Ų76.416%0.15841%0.413CS..EExtended strand (participates in β ladder)trans-125.1124.3-179.8-66.2-178.4173.379.63.4110.7A15 T16 T32 I154 N155 F157 T158A15-R34 CarbonylContact C-O 3.56Å; A15-R34 WeakPolarHBondContact CA-O 3.4Å; T16-R34 PolarHBondContact N-O 3.32Å; T16-R34 PolarHBondContact O-N 3.49Å; T16-R34 PolarHBondContact OG1-O 2.9Å; T32-R34 HydrophobicContact CG2-CG 4.29Å; R34-I154 PolarHBondContact NH2-O 3.1Å; R34-I154 VanDerWaalsContact NH2-O 3.07Å; R34-N155 VanDerWaalsContact NH2-C 3.28Å; R34-N155 PolarHBondContact NH2-O 3.38Å; R34-F157 PolarHBondContact NH2-O 3.25Å; R34-T158 WeakPolarHBondContact CD-OG1 3.43Å; R34-T158 PolarHBondContact NE-OG1 3.4Å
35A95.6Very high92.8Very high58 Ų5877.7 Ų77.748%0.47942%0.417SS..  trans-130.8137.4174.400000109.9A13 A15A13-A35 HydrophobicContact CB-CB 4.19Å; A15-A35 HydrophobicContact CB-CB 4.01Å
36T94.9Very high93.5Very high111 Ų11172.9 Ų72.968%0.68138%0.382SS*.  trans-107.2119.5177.5-55.10000109.8A13 T38A13-T36 WeakPolarHBondContact CB-O 3.36Å; T36-T38 HydrophobicContact CG2-CG2 4.02Å
37M94.7Very high93.9Very high47 Ų4769.8 Ų69.823%0.23237%0.365CS..  trans-77.7137.2165.1-57.7-178.3-16000108.1Y2 M40 Y48 F62Y2-M37 HydrophobicContact CD1-CG 3.96Å; Y2-M37 HydrophobicContact CD1-SD 4.06Å; Y2-M37 HydrophobicContact CD2-CG 4.24Å; Y2-M37 HydrophobicContact CD2-SD 3.79Å; Y2-M37 HydrophobicContact CE1-CB 4.49Å; Y2-M37 HydrophobicContact CE1-CG 4.05Å; Y2-M37 HydrophobicContact CE2-CB 4.26Å; Y2-M37 HydrophobicContact CE2-CG 4.33Å; Y2-M37 HydrophobicContact CE2-SD 4.41Å; Y2-M37 HydrophobicContact CG-CE 4.27Å; Y2-M37 HydrophobicContact CG-CG 4.07Å; Y2-M37 HydrophobicContact CG-SD 3.61Å; M37-M40 HydrophobicContact CB-CG 4.4Å; M37-M40 HydrophobicContact CB-SD 3.72Å; M37-M40 HydrophobicContact SD-CE 4.39Å; M37-Y48 HydrophobicContact CE-CD1 4.39Å; M37-Y48 HydrophobicContact CE-CD2 4.16Å; M37-Y48 HydrophobicContact CE-CG 3.8Å; M37-F62 HydrophobicContact CE-CE1 4.32Å; M37-F62 HydrophobicContact SD-CE1 3.94Å; M37-F62 HydrophobicContact SD-CZ 4.14Å
38T92.2Very high94.6Very high85 Ų8571.2 Ų71.252%0.52137%0.368SS..  trans-128.1160.9-176.1610000110.3T36 M40T36-T38 HydrophobicContact CG2-CG2 4.02Å; T38-M40 VanDerWaalsContact C-N 3.29Å; T38-M40 PolarHBondContact O-N 2.86Å
39K88.9Confident94.8Very high200 Ų20069 Ų6987%0.8736%0.361SS*.SBendtrans58.139.8178.2-52.9179-179.7-179.60113.1
40M92.7Very high95Very high39 Ų3969 Ų6919%0.19236%0.361CS..PPolyproline II helixtrans-75.9144.1174.9-51.1-167.57100109.6M37 T38 Y46 F62 Q64M37-M40 HydrophobicContact CB-CG 4.4Å; M37-M40 HydrophobicContact CB-SD 3.72Å; M37-M40 HydrophobicContact SD-CE 4.39Å; T38-M40 VanDerWaalsContact C-N 3.29Å; T38-M40 PolarHBondContact O-N 2.86Å; M40-Y46 WeakPolarHBondContact CA-OH 3.31Å; M40-Y46 HydrophobicContact CB-CE2 3.99Å; M40-Y46 HydrophobicContact CE-CD1 3.63Å; M40-Y46 HydrophobicContact CE-CD2 3.09Å; M40-Y46 HydrophobicContact CE-CE1 3.97Å; M40-Y46 HydrophobicContact CE-CE2 3.45Å; M40-Y46 VanDerWaalsContact CE-CE2 3.45Å; M40-Y46 HydrophobicContact CE-CG 3.17Å; M40-F62 HydrophobicContact CE-CE1 4.13Å; M40-F62 HydrophobicContact CE-CE2 3.55Å; M40-F62 HydrophobicContact CE-CZ 3.17Å; M40-F62 HydrophobicContact SD-CE2 4.05Å; M40-F62 HydrophobicContact SD-CZ 3.69Å; M40-Q64 HydrophobicContact CB-CG 4.21Å
41V94.2Very high95Very high75 Ų7570.6 Ų70.646%0.45539%0.386SS..PPolyproline II helixtrans-94.8126.5-178.4-179.80000108.3G43 D44 Y46 Q64V41-G43 PolarHBondContact O-N 2.81Å; V41-D44 HydrophobicContact CB-CB 4.5Å; V41-D44 WeakPolarHBondContact CB-OD2 3.4Å; V41-D44 PolarHBondContact O-N 3.46Å; V41-Y46 PolarHBondContact N-OH 2.78Å; V41-Q64 WeakPolarHBondContact O-CG 3.49Å
42P93.1Very high94.9Very high71 Ų7166.5 Ų66.546%0.46138%0.38SS..THydrogen-bonded Turntrans-53.6136172.4-28.137000112.7P65P42-P65 WeakPolarHBondContact CA-O 3.21Å; P42-P65 WeakPolarHBondContact CB-O 3.33Å
43G92.2Very high94.6Very high29 Ų2971.7 Ų71.730%0.29942%0.417SS..THydrogen-bonded Turntrans87.2-9.9-179.500000115.4V41 H63 Q64 P65V41-G43 PolarHBondContact O-N 2.81Å; G43-H63 PolarHBondContact O-CE1 2.79Å; G43-Q64 CarbonylContact C-O 3.56Å; G43-Q64 WeakPolarHBondContact CA-O 3.36Å; G43-Q64 PolarHBondContact N-O 2.85Å; G43-P65 PolarHBondContact N-O 3.46Å
44D95.1Very high94.4Very high57 Ų5774.4 Ų74.431%0.30543%0.43SS..  trans-86146179.2-83.7-15.6000112.5L4 V41 Y46 Q64L4-D44 HydrophobicContact CD2-CB 3.85Å; V41-D44 HydrophobicContact CB-CB 4.5Å; V41-D44 WeakPolarHBondContact CB-OD2 3.4Å; V41-D44 PolarHBondContact O-N 3.46Å; D44-Y46 HydrophobicContact CB-CD2 4.21Å; D44-Y46 HydrophobicContact CB-CE2 3.55Å; D44-Q64 WeakPolarHBondContact O-CB 3.26Å; D44-Q64 PolarHBondContact O-N 3.08Å
45T95.7Very high94.3Very high49 Ų4978.4 Ų78.430%0.30145%0.454SS..EExtended strand (participates in β ladder)trans-93.6128.1168.5-63.10000110.3Y47 H61 F62T45-Y47 HydrophobicContact CG2-CE2 4.06Å; T45-H61 HydrophobicContact CG2-CB 4.18Å; T45-F62 WeakPolarHBondContact CA-O 3.46Å
46Y97.4Very high94.2Very high7 Ų779 Ų793%0.02745%0.448CS..EExtended strand (participates in β ladder)trans-111.7125.2179.9-70.4-93.3000110.9Y2 G3 L4 W11 M40 V41 D44 H61 F62 Q64Y2-Y46 HydrophobicContact CD2-CD1 4.22Å; G3-Y46 WeakPolarHBondContact O-CA 3.28Å; L4-Y46 HydrophobicContact CD2-CD1 3.98Å; L4-Y46 HydrophobicContact CD2-CE1 3.62Å; L4-Y46 HydrophobicContact CD2-CE2 4.35Å; L4-Y46 HydrophobicContact CD2-CG 4.47Å; L4-Y46 HydrophobicContact CG-CE1 4.43Å; W11-Y46 HydrophobicContact CZ3-CD1 4.18Å; W11-Y46 AromaticContact CZ3-CE1 3.79Å; W11-Y46 HydrophobicContact CZ3-CE1 3.79Å; M40-Y46 WeakPolarHBondContact CA-OH 3.31Å; M40-Y46 HydrophobicContact CB-CE2 3.99Å; M40-Y46 HydrophobicContact CE-CD1 3.63Å; M40-Y46 HydrophobicContact CE-CD2 3.09Å; M40-Y46 HydrophobicContact CE-CE1 3.97Å; M40-Y46 HydrophobicContact CE-CE2 3.45Å; M40-Y46 VanDerWaalsContact CE-CE2 3.45Å; M40-Y46 HydrophobicContact CE-CG 3.17Å; V41-Y46 PolarHBondContact N-OH 2.78Å; D44-Y46 HydrophobicContact CB-CD2 4.21Å; D44-Y46 HydrophobicContact CB-CE2 3.55Å; Y46-H61 CarbonylContact O-C 3.59Å; Y46-H61 WeakPolarHBondContact O-CA 3.26Å; Y46-H61 WeakPolarHBondContact O-CB 3.4Å; Y46-F62 PolarHBondContact N-O 3.31Å; Y46-F62 PolarHBondContact O-N 3.49Å; Y46-Q64 HydrophobicContact CD2-CB 4.17Å; Y46-Q64 HydrophobicContact CE2-CB 4.01Å
47Y98.2Very high94.3Very high65 Ų6575 Ų7526%0.25543%0.425SS..EExtended strand (participates in β ladder)trans-91143.9172-62.9-95.9000109.3Y2 G3 K6 L9 T45 V59 Y60 H61Y2-Y47 CarbonylContact C-O 3.5Å; Y2-Y47 WeakPolarHBondContact CA-O 3.33Å; Y2-Y47 WeakPolarHBondContact CB-O 3.43Å; G3-Y47 PolarHBondContact N-O 3.47Å; G3-Y47 PolarHBondContact O-N 3.43Å; K6-Y47 HydrophobicContact CB-CD1 3.72Å; K6-Y47 HydrophobicContact CB-CE1 3.95Å; K6-Y47 HydrophobicContact CB-CG 4.2Å; K6-Y47 HydrophobicContact CG-CD1 4.17Å; L9-Y47 WeakPolarHBondContact CD2-O 3.34Å; T45-Y47 HydrophobicContact CG2-CE2 4.06Å; Y47-V59 HydrophobicContact CD1-CG1 4.15Å; Y47-Y60 CarbonylContact C-O 3.49Å; Y47-Y60 VanDerWaalsContact CA-O 3.28Å; Y47-Y60 WeakPolarHBondContact CA-O 3.31Å; Y47-H61 HydrophobicContact CD1-CB 3.61Å; Y47-H61 HydrophobicContact CE1-CB 3.85Å; Y47-H61 HydrophobicContact CG-CB 4.05Å
48Y98.1Very high94.4Very high37 Ų3778.6 Ų78.615%0.14545%0.445CS..EExtended strand (participates in β ladder)trans-149.8156.4-178.875.4-86.8000113.9M1 M37 V50 V59 Y60 F62 A133M1-Y48 VanDerWaalsContact O-CA 3.28Å; M1-Y48 WeakPolarHBondContact O-CA 3.14Å; M1-Y48 WeakPolarHBondContact O-CB 3.39Å; M37-Y48 HydrophobicContact CE-CD1 4.39Å; M37-Y48 HydrophobicContact CE-CD2 4.16Å; M37-Y48 HydrophobicContact CE-CG 3.8Å; Y48-V50 HydrophobicContact CD2-CG1 4.03Å; Y48-V50 HydrophobicContact CE2-CG1 4.06Å; Y48-V59 WeakPolarHBondContact O-CA 3.33Å; Y48-Y60 VanDerWaalsContact CE1-CB 3.43Å; Y48-Y60 HydrophobicContact CE2-CD2 4.07Å; Y48-Y60 HydrophobicContact CE2-CG 4.44Å; Y48-Y60 VanDerWaalsContact CZ-CB 3.44Å; Y48-Y60 PolarHBondContact N-O 3.2Å; Y48-Y60 PolarHBondContact O-N 3.25Å; Y48-F62 AromaticContact CD1-CD1 3.91Å; Y48-F62 HydrophobicContact CD1-CD1 3.91Å; Y48-F62 HydrophobicContact CD1-CE1 4.19Å; Y48-F62 AromaticContact CE1-CD1 3.91Å; Y48-F62 HydrophobicContact CE1-CD1 3.91Å; Y48-F62 HydrophobicContact CE1-CE1 4.47Å; Y48-A133 WeakPolarHBondContact OH-CA 3.49Å; Y48-A133 PolarHBondContact OH-O 3.47Å
49K97.1Very high94.7Very high69 Ų6976 Ų7630%0.343%0.429SS..  trans-130141.6168.3-76.7-177.7151.2176.30109.6M1 L9 M56 S57 V59M1-K49 PolarHBondContact N-O 2.87Å; M1-K49 PolarHBondContact O-N 2.76Å; L9-K49 HydrophobicContact CD1-CB 3.98Å; L9-K49 HydrophobicContact CD1-CD 3.96Å; L9-K49 HydrophobicContact CD1-CG 3.75Å; K49-M56 HydrophobicContact CB-CE 3.54Å; K49-M56 HydrophobicContact CD-CE 4.37Å; K49-S57 WeakPolarHBondContact CE-O 3.29Å; K49-V59 HydrophobicContact CD-CG2 3.97Å; K49-V59 HydrophobicContact CG-CB 4.35Å; K49-V59 HydrophobicContact CG-CG2 3.91Å
50V96.9Very high95.1Very high84 Ų8467.9 Ų67.951%0.50939%0.393SS..  trans-113.3147.6173-65.10000109.5Y48 S57Y48-V50 HydrophobicContact CD2-CG1 4.03Å; Y48-V50 HydrophobicContact CE2-CG1 4.06Å; V50-S57 PolarHBondContact N-OG 2.89Å; V50-S57 WeakPolarHBondContact O-CB 3.36Å; V50-S57 PolarHBondContact O-N 3Å; V50-S57 PolarHBondContact O-OG 2.9Å
51G95.3Very high95.3Very high61 Ų6169.5 Ų69.563%0.62940%0.4SS*.BIsolated β-bridgetrans152.4-165.8-178.600000113.1D55G51-D55 CarbonylContact C-O 3.55Å; G51-D55 VanDerWaalsContact CA-O 3.3Å; G51-D55 WeakPolarHBondContact CA-O 3.28Å
52S93.3Very high95.4Very high65 Ų6567.4 Ų67.446%0.45539%0.385SS..  trans-137.2-171.5-179.475.40000110.6Q54 D55S52-Q54 PolarHBondContact O-N 3.11Å; S52-Q54 PolarHBondContact OG-N 2.86Å; S52-Q54 VanDerWaalsContact OG-N 3.17Å; S52-D55 PolarHBondContact N-O 2.81Å; S52-D55 VanDerWaalsContact O-O 3.04Å
53S89.3Confident95.4Very high130 Ų13067 Ų6791%0.90938%0.377SS*.SBendtrans-66.3-14.6172.756.40000113.8
54Q91.8Very high95.3Very high181 Ų18168.2 Ų68.285%0.84638%0.375SS*.SBendtrans-87.4-37.6-180-64.3-178.6-7.200112.3S52S52-Q54 PolarHBondContact O-N 3.11Å; S52-Q54 PolarHBondContact OG-N 2.86Å; S52-Q54 VanDerWaalsContact OG-N 3.17Å
55D93.5Very high94.7Very high126 Ų12666.5 Ų66.567%0.67437%0.367SS*.  trans-160.1153.5-177.5-1606.4000111.1G51 S52G51-D55 CarbonylContact C-O 3.55Å; G51-D55 VanDerWaalsContact CA-O 3.3Å; G51-D55 WeakPolarHBondContact CA-O 3.28Å; S52-D55 PolarHBondContact N-O 2.81Å; S52-D55 VanDerWaalsContact O-O 3.04Å
56M94.6Very high94.4Very high70 Ų7066.5 Ų66.535%0.34537%0.365SS..BIsolated β-bridgetrans-136.5138.2-178.2-69.4-66.1-53.700110.1K49K49-M56 HydrophobicContact CB-CE 3.54Å; K49-M56 HydrophobicContact CD-CE 4.37Å
57S96.8Very high93.8Very high27 Ų2769.3 Ų69.319%0.18938%0.384CS..PPolyproline II helixtrans-62.7167.9172.976.10000112.6K49 V50K49-S57 WeakPolarHBondContact CE-O 3.29Å; V50-S57 PolarHBondContact N-OG 2.89Å; V50-S57 WeakPolarHBondContact O-CB 3.36Å; V50-S57 PolarHBondContact O-N 3Å; V50-S57 PolarHBondContact O-OG 2.9Å
58D96.4Very high93.3Very high123 Ų12371.3 Ų71.366%0.65840%0.403SS*.PPolyproline II helixtrans-55.6162.6157.8-72.2-39000112.2Y60D58-Y60 WeakPolarHBondContact O-CD2 3.4Å; D58-Y60 PolarHBondContact O-N 3.49Å
59V97.7Very high93Very high32 Ų3275.2 Ų75.219%0.19442%0.423CS..PPolyproline II helixtrans-78.4118172-170.10000109.1K6 Y47 Y48 K49K6-V59 HydrophobicContact CG-CB 4.11Å; K6-V59 HydrophobicContact CG-CG1 3.87Å; K6-V59 HydrophobicContact CG-CG2 4.13Å; Y47-V59 HydrophobicContact CD1-CG1 4.15Å; Y48-V59 WeakPolarHBondContact O-CA 3.33Å; K49-V59 HydrophobicContact CD-CG2 3.97Å; K49-V59 HydrophobicContact CG-CB 4.35Å; K49-V59 HydrophobicContact CG-CG2 3.91Å
60Y97.9Very high92.9Very high28 Ų2874.1 Ų74.111%0.1142%0.422CS..EExtended strand (participates in β ladder)trans-99.5172.2168.2-59.6-73.1000110.2Y47 Y48 D58 Q129 A133 Y134Y47-Y60 CarbonylContact C-O 3.49Å; Y47-Y60 VanDerWaalsContact CA-O 3.28Å; Y47-Y60 WeakPolarHBondContact CA-O 3.31Å; Y48-Y60 VanDerWaalsContact CE1-CB 3.43Å; Y48-Y60 HydrophobicContact CE2-CD2 4.07Å; Y48-Y60 HydrophobicContact CE2-CG 4.44Å; Y48-Y60 VanDerWaalsContact CZ-CB 3.44Å; Y48-Y60 PolarHBondContact N-O 3.2Å; Y48-Y60 PolarHBondContact O-N 3.25Å; D58-Y60 WeakPolarHBondContact O-CD2 3.4Å; D58-Y60 PolarHBondContact O-N 3.49Å; Y60-Q129 PolarHBondContact OH-NE2 2.94Å; Y60-A133 HydrophobicContact CD1-CB 3.57Å; Y60-A133 HydrophobicContact CE1-CB 3.95Å; Y60-A133 HydrophobicContact CG-CB 3.93Å; Y60-Y134 HydrophobicContact CD1-CE1 4.32Å; Y60-Y134 AromaticContact CD1-CE2 3.92Å; Y60-Y134 HydrophobicContact CD1-CE2 3.92Å; Y60-Y134 AromaticContact CD1-CZ 3.69Å; Y60-Y134 HydrophobicContact CE1-CE2 4.39Å
61H97.3Very high92.8Very high73 Ų7370.4 Ų70.434%0.33840%0.4SS..EExtended strand (participates in β ladder)trans-150.3155.3171.368.6-82.7000111.1T45 Y46 Y47 Y134T45-H61 HydrophobicContact CG2-CB 4.18Å; Y46-H61 CarbonylContact O-C 3.59Å; Y46-H61 WeakPolarHBondContact O-CA 3.26Å; Y46-H61 WeakPolarHBondContact O-CB 3.4Å; Y47-H61 HydrophobicContact CD1-CB 3.61Å; Y47-H61 HydrophobicContact CE1-CB 3.85Å; Y47-H61 HydrophobicContact CG-CB 4.05Å; H61-Y134 AromaticContact CE1-CD1 3.54Å; H61-Y134 AromaticContact CE1-CE1 3.65Å; H61-Y134 AromaticContact ND1-CD1 3.63Å; H61-Y134 AromaticContact ND1-CE1 3.57Å; H61-Y134 VanDerWaalsContact O-CA 3.25Å; H61-Y134 WeakPolarHBondContact O-CA 3.46Å; H61-Y134 VanDerWaalsContact O-CD1 3.23Å; H61-Y134 WeakPolarHBondContact O-CD1 3.47Å
62F95.6Very high92.9Very high32 Ų3270 Ų7014%0.1438%0.379CS..EExtended strand (participates in β ladder)trans-139.4155.9168.967.3-84.5000110.3M37 M40 T45 Y46 Y48 Y134M37-F62 HydrophobicContact CE-CE1 4.32Å; M37-F62 HydrophobicContact SD-CE1 3.94Å; M37-F62 HydrophobicContact SD-CZ 4.14Å; M40-F62 HydrophobicContact CE-CE1 4.13Å; M40-F62 HydrophobicContact CE-CE2 3.55Å; M40-F62 HydrophobicContact CE-CZ 3.17Å; M40-F62 HydrophobicContact SD-CE2 4.05Å; M40-F62 HydrophobicContact SD-CZ 3.69Å; T45-F62 WeakPolarHBondContact CA-O 3.46Å; Y46-F62 PolarHBondContact N-O 3.31Å; Y46-F62 PolarHBondContact O-N 3.49Å; Y48-F62 AromaticContact CD1-CD1 3.91Å; Y48-F62 HydrophobicContact CD1-CD1 3.91Å; Y48-F62 HydrophobicContact CD1-CE1 4.19Å; Y48-F62 AromaticContact CE1-CD1 3.91Å; Y48-F62 HydrophobicContact CE1-CD1 3.91Å; Y48-F62 HydrophobicContact CE1-CE1 4.47Å; F62-Y134 WeakPolarHBondContact CA-O 3.45Å; F62-Y134 VanDerWaalsContact CB-O 3.23Å; F62-Y134 WeakPolarHBondContact CB-O 3.34Å
63H92.6Very high93.1Very high61 Ų6166.9 Ų66.928%0.28236%0.358SS..EExtended strand (participates in β ladder)trans-90.9123.6174.2-176.965.4000109.6G43 P65G43-H63 PolarHBondContact O-CE1 2.79Å; H63-P65 WeakPolarHBondContact O-CD 3.45Å
64Q91.3Very high93.6Very high56 Ų5660.7 Ų60.726%0.26231%0.314SS..PPolyproline II helixtrans-77.3118.3166.6-177.965.613.600107M40 V41 G43 D44 Y46M40-Q64 HydrophobicContact CB-CG 4.21Å; V41-Q64 WeakPolarHBondContact O-CG 3.49Å; G43-Q64 CarbonylContact C-O 3.56Å; G43-Q64 WeakPolarHBondContact CA-O 3.36Å; G43-Q64 PolarHBondContact N-O 2.85Å; D44-Q64 WeakPolarHBondContact O-CB 3.26Å; D44-Q64 PolarHBondContact O-N 3.08Å; Y46-Q64 HydrophobicContact CD2-CB 4.17Å; Y46-Q64 HydrophobicContact CE2-CB 4.01Å
65P82.3Confident93.9Very high20 Ų2052.1 Ų52.113%0.1327%0.274CS..PPolyproline II helixtrans-61144.5-175.527.1-41.5000113.9P42 G43 H63 Y175P42-P65 WeakPolarHBondContact CA-O 3.21Å; P42-P65 WeakPolarHBondContact CB-O 3.33Å; G43-P65 PolarHBondContact N-O 3.46Å; H63-P65 WeakPolarHBondContact O-CD 3.45Å; P65-Y175 HydrophobicContact CB-CD1 4.07Å; P65-Y175 HydrophobicContact CB-CE1 3.11Å; P65-Y175 HydrophobicContact CB-CE2 4.42Å; P65-Y175 WeakPolarHBondContact CB-OH 3.46Å; P65-Y175 VanDerWaalsContact CD-OH 3.25Å; P65-Y175 WeakPolarHBondContact CD-OH 3.22Å; P65-Y175 HydrophobicContact CG-CD1 4.09Å; P65-Y175 HydrophobicContact CG-CD2 4.45Å; P65-Y175 HydrophobicContact CG-CE1 3.32Å; P65-Y175 HydrophobicContact CG-CE2 3.77Å; P65-Y175 WeakPolarHBondContact CG-OH 3.21Å
66D89.1Confident94.1Very high49 Ų4946.1 Ų46.126%0.26224%0.242SC..PPolyproline II helixtrans-88.6117.3164.4178.3-7000109.4T68 Q69D66-T68 PolarHBondContact O-N 2.93Å; D66-T68 WeakPolarHBondContact OD1-CB 3.28Å; D66-T68 WeakPolarHBondContact OD1-CG2 3.38Å; D66-T68 PolarHBondContact OD1-N 2.95Å; D66-T68 PolarHBondContact OD1-OG1 3.49Å; D66-T68 PolarHBondContact OD2-OG1 2.71Å; D66-Q69 HydrophobicContact CB-CB 4.45Å; D66-Q69 HydrophobicContact CB-CG 3.86Å; D66-Q69 PolarHBondContact O-N 2.8Å
67P84.9Confident94.2Very high66 Ų6642.8 Ų42.843%0.42923%0.226SC..THydrogen-bonded Turntrans-65.2-9.8-178.729.1-37000113.9
68T87.6Confident94.2Very high108 Ų10841.5 Ų41.566%0.66322%0.217SC*.THydrogen-bonded Turntrans-85.3-13.217473.70000113.4D66D66-T68 PolarHBondContact O-N 2.93Å; D66-T68 WeakPolarHBondContact OD1-CB 3.28Å; D66-T68 WeakPolarHBondContact OD1-CG2 3.38Å; D66-T68 PolarHBondContact OD1-N 2.95Å; D66-T68 PolarHBondContact OD1-OG1 3.49Å; D66-T68 PolarHBondContact OD2-OG1 2.71Å
69Q91.3Very high94.3Very high119 Ų11935.6 Ų35.656%0.55619%0.185SC*.SBendtrans-92.6154.6179.4-61.5-57.6-40.300111.9D66 L71D66-Q69 HydrophobicContact CB-CB 4.45Å; D66-Q69 HydrophobicContact CB-CG 3.86Å; D66-Q69 PolarHBondContact O-N 2.8Å; Q69-L71 PolarHBondContact O-N 2.88Å
70P94.9Very high94.1Very high45 Ų4534.7 Ų34.729%0.29218%0.18SC..PPolyproline II helixtrans-58124.1172.1-26.636.3000112V335P70-V335 CarbonylContact C-O 3.57Å; P70-V335 WeakPolarHBondContact CA-O 3.39Å; P70-V335 WeakPolarHBondContact CB-O 3.22Å
71L95.7Very high93.9Very high7 Ų735.9 Ų35.94%0.03719%0.19CC..EExtended strand (participates in β ladder)trans-72.9135.9174.316665000110.4Q69 D101 V102 Y175 F180 K334 V335Q69-L71 PolarHBondContact O-N 2.88Å; L71-D101 HydrophobicContact CD1-CB 4.02Å; L71-V102 HydrophobicContact CD1-CG1 4.1Å; L71-Y175 HydrophobicContact CD1-CD1 3.33Å; L71-Y175 HydrophobicContact CD1-CE1 3.43Å; L71-Y175 VanDerWaalsContact CD1-CE1 3.43Å; L71-Y175 HydrophobicContact CD1-CG 4.08Å; L71-Y175 HydrophobicContact CD2-CD1 4.34Å; L71-Y175 HydrophobicContact CG-CD1 4.32Å; L71-F180 HydrophobicContact CD2-CE2 3.55Å; L71-F180 HydrophobicContact CD2-CZ 3.7Å; L71-K334 CarbonylContact O-C 3.51Å; L71-K334 VanDerWaalsContact O-CA 3.27Å; L71-K334 WeakPolarHBondContact O-CA 3.43Å; L71-V335 HydrophobicContact CB-CB 4.21Å; L71-V335 HydrophobicContact CD2-CG2 4.4Å; L71-V335 PolarHBondContact N-O 2.81Å; L71-V335 VanDerWaalsContact N-O 3.11Å; L71-V335 PolarHBondContact O-N 2.83Å
72R97.1Very high93.6Very high52 Ų5241.8 Ų41.820%0.19621%0.211CC..EExtended strand (participates in β ladder)trans-124.6127.8174.8-53.2161.7-64.7175.18.9109.6N98 H99 D101 V102 L333 K334R72-N98 PolarHBondContact NH1-O 2.86Å; R72-N98 PolarHBondContact NH2-O 3.14Å; R72-N98 PolarHBondContact NH2-OD1 2.92Å; R72-H99 VanDerWaalsContact CB-O 3.27Å; R72-H99 WeakPolarHBondContact CB-O 3.49Å; R72-D101 WeakPolarHBondContact CA-OD2 3.33Å; R72-D101 VanDerWaalsContact CB-OD2 3.3Å; R72-D101 WeakPolarHBondContact CB-OD2 3.46Å; R72-D101 IonicContact CZ-OD1 3.78Å; R72-D101 IonicContact CZ-OD2 2.92Å; R72-D101 PolarHBondContact N-OD2 3.38Å; R72-D101 IonicContact NE-OD1 3.23Å; R72-D101 IonicContact NE-OD2 2.81Å; R72-D101 PolarHBondContact NE-OD2 3Å; R72-D101 IonicContact NH2-OD1 3.76Å; R72-D101 PolarHBondContact NH2-OD1 2.94Å; R72-D101 IonicContact NH2-OD2 3.8Å; R72-D101 PolarHBondContact O-N 3Å; R72-V102 PolarHBondContact O-N 2.83Å; R72-L333 CarbonylContact C-O 3.43Å; R72-L333 WeakPolarHBondContact CA-O 3.42Å; R72-K334 HydrophobicContact CG-CD 4.45Å; R72-K334 HydrophobicContact CG-CG 4.36Å
73A98.2Very high93.4Very high0 Ų045.2 Ų45.20%023%0.226CC..EExtended strand (participates in β ladder)trans-131.1149.9178.600000112.2I75 V102 R332 L333A73-I75 HydrophobicContact CB-CG1 4.36Å; A73-V102 VanDerWaalsContact CA-O 3.22Å; A73-V102 WeakPolarHBondContact CA-O 3.41Å; A73-V102 HydrophobicContact CB-CG1 3.58Å; A73-R332 CarbonylContact O-C 3.54Å; A73-R332 WeakPolarHBondContact O-CA 3.3Å; A73-L333 HydrophobicContact CB-CB 4.27Å; A73-L333 HydrophobicContact CB-CD2 4.43Å; A73-L333 PolarHBondContact N-O 2.9Å; A73-L333 PolarHBondContact O-N 3.37Å
74A98.4Very high93.4Very high0 Ų042.3 Ų42.30%021%0.212CC..EExtended strand (participates in β ladder)trans-102.2132.515900000108.8L91 F100 V102 I103 I104 Y330 T331A74-L91 HydrophobicContact CB-CD2 3.82Å; A74-F100 HydrophobicContact CB-CD1 3.93Å; A74-F100 HydrophobicContact CB-CD2 4.34Å; A74-F100 HydrophobicContact CB-CE1 3.76Å; A74-F100 HydrophobicContact CB-CE2 4.16Å; A74-F100 HydrophobicContact CB-CG 4.24Å; A74-F100 HydrophobicContact CB-CZ 3.88Å; A74-V102 PolarHBondContact N-O 3.28Å; A74-I103 HydrophobicContact CB-CG1 4.27Å; A74-I103 HydrophobicContact CB-CG2 4.39Å; A74-I103 CarbonylContact O-C 3.58Å; A74-I103 WeakPolarHBondContact O-CA 3.34Å; A74-I104 PolarHBondContact O-N 2.98Å; A74-Y330 HydrophobicContact CB-CD2 3.93Å; A74-Y330 HydrophobicContact CB-CE2 4.2Å; A74-T331 CarbonylContact C-O 3.48Å; A74-T331 WeakPolarHBondContact CA-O 3.48Å
75I98.8Very high93.5Very high0 Ų042 Ų420%022%0.219CC..EExtended strand (participates in β ladder)trans-131.3125.4179.7-49.7176.9000108.3A73 I104 I106 L264 T302 T331 L333A73-I75 HydrophobicContact CB-CG1 4.36Å; I75-I104 WeakPolarHBondContact CA-O 3.41Å; I75-I104 HydrophobicContact CG1-CB 4.33Å; I75-I104 HydrophobicContact CG1-CD1 4.43Å; I75-I104 HydrophobicContact CG2-CB 4.4Å; I75-I106 HydrophobicContact CG2-CG2 3.85Å; I75-L264 HydrophobicContact CB-CD2 4.29Å; I75-L264 HydrophobicContact CD1-CD2 4.06Å; I75-L264 HydrophobicContact CG2-CD2 4.03Å; I75-T302 HydrophobicContact CG2-CG2 4.44Å; I75-T331 PolarHBondContact N-O 3.12Å; I75-T331 WeakPolarHBondContact O-CB 3.24Å; I75-T331 PolarHBondContact O-N 2.69Å; I75-L333 HydrophobicContact CD1-CB 4.27Å; I75-L333 HydrophobicContact CD1-CD2 4.07Å
76F98Very high94Very high0 Ų044 Ų440%023%0.232CC..EExtended strand (participates in β ladder)trans-158.8154.5-177.559-96.3000111.3L79 L91 I103 I104 H105 I106 Y137 A305F76-L79 HydrophobicContact CD2-CB 4.32Å; F76-L79 HydrophobicContact CD2-CD2 4.4Å; F76-L79 HydrophobicContact CE2-CB 4.13Å; F76-L79 HydrophobicContact CE2-CD2 3.61Å; F76-L79 HydrophobicContact CE2-CG 4.46Å; F76-L79 HydrophobicContact CZ-CD2 4.14Å; F76-L91 HydrophobicContact CD1-CD1 4.14Å; F76-L91 HydrophobicContact CD1-CD2 4.28Å; F76-L91 HydrophobicContact CE1-CD1 3.44Å; F76-L91 VanDerWaalsContact CE1-CD1 3.44Å; F76-L91 HydrophobicContact CE1-CD2 3.84Å; F76-L91 HydrophobicContact CE1-CG 4.31Å; F76-L91 HydrophobicContact CE2-CD1 4.42Å; F76-L91 HydrophobicContact CZ-CD1 3.61Å; F76-I103 HydrophobicContact CD1-CG2 4.46Å; F76-I103 HydrophobicContact CE1-CG2 3.44Å; F76-I103 VanDerWaalsContact CE1-CG2 3.44Å; F76-I103 HydrophobicContact CZ-CG2 3.9Å; F76-I104 PolarHBondContact N-O 3.34Å; F76-I104 VanDerWaalsContact N-O 3.11Å; F76-H105 AromaticContact CD2-CD2 3.79Å; F76-H105 HydrophobicContact CE2-CB 4.15Å; F76-H105 AromaticContact CE2-CD2 3.77Å; F76-H105 AromaticContact CE2-CG 3.74Å; F76-H105 CarbonylContact O-C 3.59Å; F76-H105 VanDerWaalsContact O-CA 3.23Å; F76-H105 WeakPolarHBondContact O-CA 3.27Å; F76-H105 PolarHBondContact O-CD2 3.04Å; F76-H105 VanDerWaalsContact O-CD2 3.32Å; F76-I106 WeakPolarHBondContact O-CG1 3.37Å; F76-I106 PolarHBondContact O-N 2.75Å; F76-Y137 HydrophobicContact CZ-CE2 4.09Å; F76-A305 HydrophobicContact CB-CB 3.98Å; F76-A305 HydrophobicContact CD2-CB 3.75Å; F76-A305 HydrophobicContact CG-CB 4.15Å
77G97.3Very high94.3Very high0 Ų041.7 Ų41.70%022%0.22CC..  trans-115.1173.3170.800000110.6I106 T302 A305G77-I106 VanDerWaalsContact CA-CG1 3.43Å; G77-T302 PolarHBondContact N-O 3.25Å; G77-A305 WeakPolarHBondContact O-CB 3.4Å; G77-A305 PolarHBondContact O-N 3.4Å
78D96.8Very high94.9Very high0 Ų039.4 Ų39.40%020%0.204CC..  trans6948.5153.3-59.1-94.3000112.6H105 G107 Y111 H220 G266 H267 H269 G303 G306 C307D78-H105 PolarHBondContact N-NE2 3.36Å; D78-G107 PolarHBondContact N-O 3.09Å; D78-Y111 VanDerWaalsContact C-OH 3.31Å; D78-Y111 WeakPolarHBondContact CA-OH 3.27Å; D78-Y111 WeakPolarHBondContact CB-OH 3.47Å; D78-Y111 PolarHBondContact O-OH 3.34Å; D78-Y111 PolarHBondContact OD1-OH 3.33Å; D78-H220 IonicContact OD1-CE1 3.17Å; D78-H220 IonicContact OD2-CE1 2.74Å; D78-G266 VanDerWaalsContact OD2-CA 3.3Å; D78-G266 WeakPolarHBondContact OD2-CA 3.46Å; D78-H267 WeakPolarHBondContact OD1-CA 3.38Å; D78-H267 PolarHBondContact OD1-N 3.26Å; D78-H267 PolarHBondContact OD2-N 2.68Å; D78-H269 IonicContact OD1-CD2 2.71Å; D78-H269 PolarHBondContact OD1-CD2 2.82Å; D78-H269 IonicContact OD1-NE2 3.49Å; D78-H269 PolarHBondContact OD1-NE2 3.04Å; D78-G303 WeakPolarHBondContact CB-O 3.45Å; D78-G303 WeakPolarHBondContact OD2-CA 3.39Å; D78-G306 CarbonylContact O-C 3.41Å; D78-G306 PolarHBondContact O-N 3.13Å; D78-C307 PolarHBondContact O-N 3.07Å
79L96.8Very high95.3Very high0 Ų040 Ų400%020%0.198CC..BIsolated β-bridgetrans-107.5112.9-175.9-17566000112.1F76 I88 D108 A110 Y124 A305F76-L79 HydrophobicContact CD2-CB 4.32Å; F76-L79 HydrophobicContact CD2-CD2 4.4Å; F76-L79 HydrophobicContact CE2-CB 4.13Å; F76-L79 HydrophobicContact CE2-CD2 3.61Å; F76-L79 HydrophobicContact CE2-CG 4.46Å; F76-L79 HydrophobicContact CZ-CD2 4.14Å; L79-I88 HydrophobicContact CD1-CG1 4.26Å; L79-I88 HydrophobicContact CD2-CG1 3.99Å; L79-I88 HydrophobicContact CG-CG1 4.45Å; L79-D108 PolarHBondContact N-O 2.97Å; L79-A110 WeakPolarHBondContact O-CA 3.2Å; L79-A110 PolarHBondContact O-N 3.26Å; L79-Y124 HydrophobicContact CG-CE2 4.45Å; L79-Y124 VanDerWaalsContact O-CE2 3.26Å; L79-Y124 WeakPolarHBondContact O-CE2 3.4Å; L79-A305 HydrophobicContact CB-CB 3.87Å; L79-A305 HydrophobicContact CD1-CB 3.82Å; L79-A305 WeakPolarHBondContact CD1-O 3.41Å; L79-A305 HydrophobicContact CG-CB 4.39Å
80S94.9Very high95.4Very high13 Ų1335.4 Ų35.49%0.09118%0.176CC..  trans-90.7165.316774.30000112K83 G84 G306S80-K83 WeakPolarHBondContact OG-CB 3.41Å; S80-K83 PolarHBondContact OG-N 3.43Å; S80-G84 WeakPolarHBondContact O-CA 3.46Å; S80-G84 PolarHBondContact O-N 3.26Å; S80-G84 PolarHBondContact OG-N 2.96Å; S80-G306 WeakPolarHBondContact CB-O 3.44Å; S80-G306 PolarHBondContact N-O 2.75Å; S80-G306 VanDerWaalsContact N-O 3.11Å; S80-G306 PolarHBondContact OG-O 3.32Å
81V93.6Very high95.5Very high53 Ų5333.3 Ų33.332%0.32116%0.162SC..SBendtrans-68.9-53.6173.1-179.30000111.4A85 Y124 A127V81-A85 PolarHBondContact O-N 3.38Å; V81-A85 VanDerWaalsContact O-N 3.17Å; V81-Y124 HydrophobicContact CG2-CD2 3.68Å; V81-Y124 HydrophobicContact CG2-CG 4.35Å; V81-A127 HydrophobicContact CG1-CB 3.99Å; V81-A127 HydrophobicContact CG2-CB 4.24Å
82Y90.9Very high95.6Very high196 Ų19633.9 Ų33.977%0.76917%0.166SC*.SBendtrans-75.5-54.3-168.9-179-106.4000112.9G84 A85Y82-G84 VanDerWaalsContact C-N 3.33Å; Y82-A85 WeakPolarHBondContact O-CB 3.1Å; Y82-A85 PolarHBondContact O-N 3.03Å
83K90.4Very high95.5Very high104 Ų10434.4 Ų34.445%0.45217%0.173SC..THydrogen-bonded Turntrans-75.1-27.1179.2-68.1-69.9-169.2170.20112S80 A85 P86 C307S80-K83 WeakPolarHBondContact OG-CB 3.41Å; S80-K83 PolarHBondContact OG-N 3.43Å; K83-A85 VanDerWaalsContact C-N 3.31Å; K83-P86 WeakPolarHBondContact O-CD 3.18Å; K83-C307 WeakPolarHBondContact CB-O 3.25Å; K83-C307 WeakPolarHBondContact CG-O 3.47Å
84G93.4Very high95.4Very high0 Ų034.8 Ų34.80%018%0.176CC..THydrogen-bonded Turntrans-81.6-0.617500000115.2S80 Y82 P86 S87 I88 G306S80-G84 WeakPolarHBondContact O-CA 3.46Å; S80-G84 PolarHBondContact O-N 3.26Å; S80-G84 PolarHBondContact OG-N 2.96Å; Y82-G84 VanDerWaalsContact C-N 3.33Å; G84-P86 VanDerWaalsContact C-CD 3.46Å; G84-P86 VanDerWaalsContact C-N 3.33Å; G84-S87 WeakPolarHBondContact O-CA 3.47Å; G84-S87 WeakPolarHBondContact O-CB 3.43Å; G84-S87 PolarHBondContact O-N 3.3Å; G84-I88 WeakPolarHBondContact O-CG1 3.38Å; G84-I88 PolarHBondContact O-N 3.14Å; G84-G306 PolarHBondContact N-O 3.03Å
85A93.9Very high95.4Very high49 Ų4935.2 Ų35.241%0.40518%0.179SC..Hα-helixtrans-52.2-40.8-179.200000114.3V81 Y82 K83 I88 K89V81-A85 PolarHBondContact O-N 3.38Å; V81-A85 VanDerWaalsContact O-N 3.17Å; Y82-A85 WeakPolarHBondContact O-CB 3.1Å; Y82-A85 PolarHBondContact O-N 3.03Å; K83-A85 VanDerWaalsContact C-N 3.31Å; A85-I88 PolarHBondContact O-N 3.33Å; A85-K89 WeakPolarHBondContact O-CB 2.89Å; A85-K89 PolarHBondContact O-N 2.89Å
86P93.1Very high95.2Very high62 Ų6240 Ų4040%0.40320%0.201SC..Hα-helixtrans-62-43.1173.6-23.135.2000112.9K83 G84 K89 Q90 T348K83-P86 WeakPolarHBondContact O-CD 3.18Å; G84-P86 VanDerWaalsContact C-CD 3.46Å; G84-P86 VanDerWaalsContact C-N 3.33Å; P86-K89 PolarHBondContact O-N 3.19Å; P86-Q90 WeakPolarHBondContact O-CG 3.16Å; P86-Q90 PolarHBondContact O-N 2.88Å; P86-T348 VanDerWaalsContact CB-O 3.22Å; P86-T348 WeakPolarHBondContact CB-O 2.98Å
87S95.1Very high95.1Very high2 Ų245.2 Ų45.21%0.01423%0.229CC..Hα-helixtrans-65.7-44.1177.2-59.10000112G84 K89 Q90 L91 A305 T348G84-S87 WeakPolarHBondContact O-CA 3.47Å; G84-S87 WeakPolarHBondContact O-CB 3.43Å; G84-S87 PolarHBondContact O-N 3.3Å; S87-K89 VanDerWaalsContact C-N 3.31Å; S87-K89 PolarHBondContact O-N 2.88Å; S87-Q90 PolarHBondContact O-N 2.61Å; S87-L91 WeakPolarHBondContact O-CB 3.32Å; S87-L91 VanDerWaalsContact O-CG 3.24Å; S87-L91 WeakPolarHBondContact O-CG 3.26Å; S87-L91 PolarHBondContact O-N 3.06Å; S87-A305 WeakPolarHBondContact CB-O 3.12Å; S87-A305 PolarHBondContact OG-O 3.23Å; S87-T348 WeakPolarHBondContact OG-CB 3.38Å; S87-T348 PolarHBondContact OG-OG1 3.18Å
88I96.6Very high94.9Very high17 Ų1749.4 Ų49.49%0.08725%0.251CS..Hα-helixtrans-57.7-45.9174.8-69.5167.8000110.3L79 G84 A85 L91 T92 A127 F131L79-I88 HydrophobicContact CD1-CG1 4.26Å; L79-I88 HydrophobicContact CD2-CG1 3.99Å; L79-I88 HydrophobicContact CG-CG1 4.45Å; G84-I88 WeakPolarHBondContact O-CG1 3.38Å; G84-I88 PolarHBondContact O-N 3.14Å; A85-I88 PolarHBondContact O-N 3.33Å; I88-L91 PolarHBondContact O-N 2.67Å; I88-T92 WeakPolarHBondContact O-CB 3.45Å; I88-T92 PolarHBondContact O-N 3.3Å; I88-T92 PolarHBondContact O-OG1 2.76Å; I88-A127 HydrophobicContact CD1-CB 4.17Å; I88-A127 VanDerWaalsContact CG2-O 3.29Å; I88-A127 WeakPolarHBondContact CG2-O 3.47Å; I88-F131 HydrophobicContact CG2-CE1 4.3Å
89K95.3Very high94.8Very high121 Ų12152.5 Ų52.553%0.52627%0.266SS..Hα-helixtrans-60.6-49.2177.5-169.2-165.8-179.1-46.40111.3A85 P86 S87 T92 D93A85-K89 WeakPolarHBondContact O-CB 2.89Å; A85-K89 PolarHBondContact O-N 2.89Å; P86-K89 PolarHBondContact O-N 3.19Å; S87-K89 VanDerWaalsContact C-N 3.31Å; S87-K89 PolarHBondContact O-N 2.88Å; K89-T92 WeakPolarHBondContact O-CB 3.33Å; K89-T92 PolarHBondContact O-N 3.01Å; K89-D93 VanDerWaalsContact NZ-CG 3.26Å; K89-D93 IonicContact NZ-OD1 3.73Å; K89-D93 PolarHBondContact NZ-OD1 2.87Å; K89-D93 IonicContact NZ-OD2 3.83Å; K89-D93 PolarHBondContact NZ-OD2 2.83Å; K89-D93 VanDerWaalsContact O-CG 3.28Å; K89-D93 PolarHBondContact O-N 2.74Å
90Q95.3Very high94.8Very high23 Ų2352.7 Ų52.711%0.10727%0.266CS..Hα-helixtrans-67.9-36.6-178-69.4-160.230.200112.9P86 S87 T92 A94 T348 D350P86-Q90 WeakPolarHBondContact O-CG 3.16Å; P86-Q90 PolarHBondContact O-N 2.88Å; S87-Q90 PolarHBondContact O-N 2.61Å; Q90-T92 VanDerWaalsContact C-N 3.3Å; Q90-A94 WeakPolarHBondContact O-CB 3.32Å; Q90-A94 PolarHBondContact O-N 2.95Å; Q90-T348 HydrophobicContact CB-CG2 4.28Å; Q90-T348 HydrophobicContact CG-CG2 4.44Å; Q90-D350 PolarHBondContact NE2-O 2.58Å
91L96.6Very high94.9Very high0 Ų052.8 Ų52.80%027%0.266CS..Hα-helixtrans-62.7-39.1172.4-73.5165.7000111.3A74 F76 S87 I88 T95 F100 F131 Y330A74-L91 HydrophobicContact CB-CD2 3.82Å; F76-L91 HydrophobicContact CD1-CD1 4.14Å; F76-L91 HydrophobicContact CD1-CD2 4.28Å; F76-L91 HydrophobicContact CE1-CD1 3.44Å; F76-L91 VanDerWaalsContact CE1-CD1 3.44Å; F76-L91 HydrophobicContact CE1-CD2 3.84Å; F76-L91 HydrophobicContact CE1-CG 4.31Å; F76-L91 HydrophobicContact CE2-CD1 4.42Å; F76-L91 HydrophobicContact CZ-CD1 3.61Å; S87-L91 WeakPolarHBondContact O-CB 3.32Å; S87-L91 VanDerWaalsContact O-CG 3.24Å; S87-L91 WeakPolarHBondContact O-CG 3.26Å; S87-L91 PolarHBondContact O-N 3.06Å; I88-L91 PolarHBondContact O-N 2.67Å; L91-T95 WeakPolarHBondContact O-CB 3.43Å; L91-T95 PolarHBondContact O-N 3.18Å; L91-T95 PolarHBondContact O-OG1 3.25Å; L91-F100 HydrophobicContact CD2-CE2 4.07Å; L91-F100 HydrophobicContact CD2-CZ 4.37Å; L91-F131 HydrophobicContact CB-CD1 4.09Å; L91-F131 HydrophobicContact CB-CE1 4.32Å; L91-F131 HydrophobicContact CB-CG 4.48Å; L91-F131 HydrophobicContact CD1-CE1 4.44Å; L91-F131 HydrophobicContact CD1-CZ 4.5Å; L91-Y330 HydrophobicContact CD2-CD1 4.08Å; L91-Y330 HydrophobicContact CD2-CD2 4.24Å; L91-Y330 HydrophobicContact CD2-CE1 4.1Å; L91-Y330 HydrophobicContact CD2-CE2 4.25Å; L91-Y330 HydrophobicContact CD2-CG 4.16Å; L91-Y330 HydrophobicContact CG-CD1 4.33Å; L91-Y330 HydrophobicContact CG-CE1 4.32Å
92T97.5Very high95.1Very high20 Ų2050.3 Ų50.312%0.12325%0.251CS..Hα-helixtrans-64.6-52.9175.8-58.50000111.4I88 K89 Q90 A94 T95 H96 P130I88-T92 WeakPolarHBondContact O-CB 3.45Å; I88-T92 PolarHBondContact O-N 3.3Å; I88-T92 PolarHBondContact O-OG1 2.76Å; K89-T92 WeakPolarHBondContact O-CB 3.33Å; K89-T92 PolarHBondContact O-N 3.01Å; Q90-T92 VanDerWaalsContact C-N 3.3Å; T92-A94 PolarHBondContact O-N 2.88Å; T92-T95 WeakPolarHBondContact O-CB 3.46Å; T92-T95 PolarHBondContact O-N 2.71Å; T92-T95 VanDerWaalsContact O-N 3.16Å; T92-H96 PolarHBondContact O-CD2 2.67Å; T92-H96 PolarHBondContact O-N 3.24Å; T92-P130 HydrophobicContact CG2-CB 3.53Å
93D95.8Very high95.4Very high62 Ų6241 Ų4133%0.33221%0.214SC..Hα-helixtrans-56.8-50178.8-64.1-18.3000110.2K89 T95 H96 D97K89-D93 VanDerWaalsContact NZ-CG 3.26Å; K89-D93 IonicContact NZ-OD1 3.73Å; K89-D93 PolarHBondContact NZ-OD1 2.87Å; K89-D93 IonicContact NZ-OD2 3.83Å; K89-D93 PolarHBondContact NZ-OD2 2.83Å; K89-D93 VanDerWaalsContact O-CG 3.28Å; K89-D93 PolarHBondContact O-N 2.74Å; D93-T95 VanDerWaalsContact C-N 3.31Å; D93-T95 PolarHBondContact O-N 3.25Å; D93-H96 PolarHBondContact O-N 2.85Å; D93-D97 PolarHBondContact O-N 3.43Å
94A95.6Very high95.8Very high8 Ų836 Ų367%0.06619%0.193CC..Hα-helixtrans-64.9-32.3179.100000113.1Q90 T92 D97 N98 H99 F100Q90-A94 WeakPolarHBondContact O-CB 3.32Å; Q90-A94 PolarHBondContact O-N 2.95Å; T92-A94 PolarHBondContact O-N 2.88Å; A94-D97 CarbonylContact O-C 3.59Å; A94-D97 PolarHBondContact O-N 3.39Å; A94-N98 PolarHBondContact O-N 2.86Å; A94-H99 HydrophobicContact CB-CB 4.03Å; A94-H99 WeakPolarHBondContact O-CB 3.4Å; A94-H99 PolarHBondContact O-N 2.78Å; A94-F100 HydrophobicContact CB-CD2 4.37Å; A94-F100 HydrophobicContact CB-CE2 3.45Å; A94-F100 VanDerWaalsContact CB-CE2 3.45Å; A94-F100 HydrophobicContact CB-CZ 3.64Å
95T96.9Very high96.1Very high9 Ų936 Ų366%0.05519%0.193CC..Hα-helixtrans-65.2-45.8173.8-67.30000111.1L91 T92 D93 D97 N98 F131 V135L91-T95 WeakPolarHBondContact O-CB 3.43Å; L91-T95 PolarHBondContact O-N 3.18Å; L91-T95 PolarHBondContact O-OG1 3.25Å; T92-T95 WeakPolarHBondContact O-CB 3.46Å; T92-T95 PolarHBondContact O-N 2.71Å; T92-T95 VanDerWaalsContact O-N 3.16Å; D93-T95 VanDerWaalsContact C-N 3.31Å; D93-T95 PolarHBondContact O-N 3.25Å; T95-D97 VanDerWaalsContact C-N 3.28Å; T95-D97 PolarHBondContact O-N 3.44Å; T95-N98 PolarHBondContact O-N 3.14Å; T95-F131 HydrophobicContact CG2-CB 4.08Å; T95-F131 WeakPolarHBondContact OG1-CB 3.45Å; T95-V135 HydrophobicContact CG2-CB 4.4Å; T95-V135 HydrophobicContact CG2-CG2 3.57Å
96H96Very high96.3Very high101 Ų10133.7 Ų33.747%0.46817%0.173SC..Hα-helixtrans-69.1-26.5177.8-67-48.9000113.2T92 D93 N98 P130 Y134T92-H96 PolarHBondContact O-CD2 2.67Å; T92-H96 PolarHBondContact O-N 3.24Å; D93-H96 PolarHBondContact O-N 2.85Å; H96-N98 PolarHBondContact O-N 2.83Å; H96-P130 PolarHBondContact CE1-O 3.43Å; H96-P130 PolarHBondContact NE2-O 2.7Å; H96-Y134 AromaticContact CE1-CD2 3.87Å; H96-Y134 AromaticContact CE1-CE2 3.69Å; H96-Y134 AromaticContact CE1-CZ 3.98Å
97D95.2Very high96.5Very high109 Ų10930.8 Ų30.858%0.58315%0.154SC*.THydrogen-bonded Turntrans-80.98.9170.3-68.7-19.4000113.3D93 A94 T95 H99D93-D97 PolarHBondContact O-N 3.43Å; A94-D97 CarbonylContact O-C 3.59Å; A94-D97 PolarHBondContact O-N 3.39Å; T95-D97 VanDerWaalsContact C-N 3.28Å; T95-D97 PolarHBondContact O-N 3.44Å; D97-H99 PolarHBondContact O-CD2 2.93Å; D97-H99 VanDerWaalsContact O-CD2 3.31Å; D97-H99 PolarHBondContact O-N 2.88Å
98N93.8Very high96.6Very high88 Ų8830.7 Ų30.747%0.47115%0.154SC..THydrogen-bonded Turntrans57.544.9178.8-173.820.4000112.4R72 A94 T95 H96R72-N98 PolarHBondContact NH1-O 2.86Å; R72-N98 PolarHBondContact NH2-O 3.14Å; R72-N98 PolarHBondContact NH2-OD1 2.92Å; A94-N98 PolarHBondContact O-N 2.86Å; T95-N98 PolarHBondContact O-N 3.14Å; H96-N98 PolarHBondContact O-N 2.83Å
99H94.9Very high96.6Very high66 Ų6629.9 Ų29.931%0.30615%0.15SC..  trans-89.5-13-179.9-73.7177.8000115R72 A94 D97 R332R72-H99 VanDerWaalsContact CB-O 3.27Å; R72-H99 WeakPolarHBondContact CB-O 3.49Å; A94-H99 HydrophobicContact CB-CB 4.03Å; A94-H99 WeakPolarHBondContact O-CB 3.4Å; A94-H99 PolarHBondContact O-N 2.78Å; D97-H99 PolarHBondContact O-CD2 2.93Å; D97-H99 VanDerWaalsContact O-CD2 3.31Å; D97-H99 PolarHBondContact O-N 2.88Å; H99-R332 PolarHBondContact O-NH2 3.44Å
100F96.3Very high96.6Very high4 Ų424.4 Ų24.42%0.01813%0.127CC..  trans-131.9142-174.6-49.2-51.8000111.4A74 L91 A94 I103 V135 Y330 R332A74-F100 HydrophobicContact CB-CD1 3.93Å; A74-F100 HydrophobicContact CB-CD2 4.34Å; A74-F100 HydrophobicContact CB-CE1 3.76Å; A74-F100 HydrophobicContact CB-CE2 4.16Å; A74-F100 HydrophobicContact CB-CG 4.24Å; A74-F100 HydrophobicContact CB-CZ 3.88Å; L91-F100 HydrophobicContact CD2-CE2 4.07Å; L91-F100 HydrophobicContact CD2-CZ 4.37Å; A94-F100 HydrophobicContact CB-CD2 4.37Å; A94-F100 HydrophobicContact CB-CE2 3.45Å; A94-F100 VanDerWaalsContact CB-CE2 3.45Å; A94-F100 HydrophobicContact CB-CZ 3.64Å; F100-I103 HydrophobicContact CB-CG1 4.3Å; F100-I103 HydrophobicContact CD2-CD1 4.21Å; F100-I103 HydrophobicContact CD2-CG1 4.24Å; F100-I103 HydrophobicContact CG-CG1 4.44Å; F100-V135 HydrophobicContact CB-CG1 4.22Å; F100-V135 HydrophobicContact CB-CG2 4.46Å; F100-Y330 HydrophobicContact CE1-CE2 4.12Å; F100-Y330 AromaticContact CZ-CE2 3.7Å; F100-Y330 HydrophobicContact CZ-CE2 3.7Å; F100-Y330 AromaticContact CZ-CZ 3.99Å; F100-R332 HydrophobicContact CE1-CG 4.25Å
101D96.1Very high96.5Very high15 Ų1523.7 Ų23.78%0.0812%0.123CC..SBendtrans-103.8-23.2171.9-48.4-61.7000110.3L71 R72 P136 Y175L71-D101 HydrophobicContact CD1-CB 4.02Å; R72-D101 WeakPolarHBondContact CA-OD2 3.33Å; R72-D101 VanDerWaalsContact CB-OD2 3.3Å; R72-D101 WeakPolarHBondContact CB-OD2 3.46Å; R72-D101 IonicContact CZ-OD1 3.78Å; R72-D101 IonicContact CZ-OD2 2.92Å; R72-D101 PolarHBondContact N-OD2 3.38Å; R72-D101 IonicContact NE-OD1 3.23Å; R72-D101 IonicContact NE-OD2 2.81Å; R72-D101 PolarHBondContact NE-OD2 3Å; R72-D101 IonicContact NH2-OD1 3.76Å; R72-D101 PolarHBondContact NH2-OD1 2.94Å; R72-D101 IonicContact NH2-OD2 3.8Å; R72-D101 PolarHBondContact O-N 3Å; D101-P136 WeakPolarHBondContact O-CD 3.4Å; D101-Y175 VanDerWaalsContact C-OH 3.25Å; D101-Y175 HydrophobicContact CB-CE1 3.82Å; D101-Y175 WeakPolarHBondContact CB-OH 3.45Å; D101-Y175 PolarHBondContact O-OH 2.88Å
102V97.8Very high96.4Very high1 Ų124.7 Ų24.71%0.00613%0.129CC..EExtended strand (participates in β ladder)trans-148.7147.6172.463.90000110.9L71 R72 A73 A74 I104 P136 M138 F173 Y175L71-V102 HydrophobicContact CD1-CG1 4.1Å; R72-V102 PolarHBondContact O-N 2.83Å; A73-V102 VanDerWaalsContact CA-O 3.22Å; A73-V102 WeakPolarHBondContact CA-O 3.41Å; A73-V102 HydrophobicContact CB-CG1 3.58Å; A74-V102 PolarHBondContact N-O 3.28Å; V102-I104 HydrophobicContact CG2-CG1 4.11Å; V102-P136 HydrophobicContact CG2-CB 4.47Å; V102-M138 HydrophobicContact CG2-CG 3.68Å; V102-F173 HydrophobicContact CG2-CZ 4.11Å; V102-Y175 HydrophobicContact CB-CD2 4.38Å; V102-Y175 HydrophobicContact CB-CE2 4.02Å
103I98.7Very high96.3Very high0 Ų023.9 Ų23.90%012%0.124CC..EExtended strand (participates in β ladder)trans-119.6131.5171.3-61.8170.4000108.1A74 F76 F100 F131 V135 P136 Y137 M138A74-I103 HydrophobicContact CB-CG1 4.27Å; A74-I103 HydrophobicContact CB-CG2 4.39Å; A74-I103 CarbonylContact O-C 3.58Å; A74-I103 WeakPolarHBondContact O-CA 3.34Å; F76-I103 HydrophobicContact CD1-CG2 4.46Å; F76-I103 HydrophobicContact CE1-CG2 3.44Å; F76-I103 VanDerWaalsContact CE1-CG2 3.44Å; F76-I103 HydrophobicContact CZ-CG2 3.9Å; F100-I103 HydrophobicContact CB-CG1 4.3Å; F100-I103 HydrophobicContact CD2-CD1 4.21Å; F100-I103 HydrophobicContact CD2-CG1 4.24Å; F100-I103 HydrophobicContact CG-CG1 4.44Å; I103-F131 HydrophobicContact CD1-CB 4.17Å; I103-F131 HydrophobicContact CD1-CD2 3.61Å; I103-F131 HydrophobicContact CD1-CE2 4.34Å; I103-F131 HydrophobicContact CD1-CG 4.2Å; I103-V135 HydrophobicContact CD1-CB 4.09Å; I103-V135 HydrophobicContact CD1-CG1 4.1Å; I103-V135 HydrophobicContact CG1-CB 4.34Å; I103-V135 HydrophobicContact CG1-CG1 3.79Å; I103-P136 PolarHBondContact N-O 3.17Å; I103-Y137 HydrophobicContact CB-CD2 4.04Å; I103-Y137 HydrophobicContact CG2-CD2 3.69Å; I103-Y137 HydrophobicContact CG2-CE2 3.87Å; I103-Y137 WeakPolarHBondContact O-CA 3.35Å; I103-M138 PolarHBondContact O-N 2.72Å
104I98.8Very high96.2Very high0 Ų023 Ų230%012%0.117CC..EExtended strand (participates in β ladder)trans-122.9119.2-178-48.6178.6000109.9A74 I75 F76 V102 I106 M138 W171 F173 F180 M218A74-I104 PolarHBondContact O-N 2.98Å; I75-I104 WeakPolarHBondContact CA-O 3.41Å; I75-I104 HydrophobicContact CG1-CB 4.33Å; I75-I104 HydrophobicContact CG1-CD1 4.43Å; I75-I104 HydrophobicContact CG2-CB 4.4Å; F76-I104 PolarHBondContact N-O 3.34Å; F76-I104 VanDerWaalsContact N-O 3.11Å; V102-I104 HydrophobicContact CG2-CG1 4.11Å; I104-I106 HydrophobicContact CG2-CG2 4.3Å; I104-M138 CarbonylContact C-O 3.58Å; I104-M138 WeakPolarHBondContact CA-O 3.27Å; I104-M138 HydrophobicContact CG1-CB 4.21Å; I104-M138 HydrophobicContact CG2-CB 4.34Å; I104-W171 HydrophobicContact CG2-CH2 4.48Å; I104-F173 HydrophobicContact CD1-CZ 4.43Å; I104-F180 HydrophobicContact CD1-CD1 3.6Å; I104-F180 HydrophobicContact CD1-CE1 3.79Å; I104-F180 HydrophobicContact CD1-CG 4.14Å; I104-F180 HydrophobicContact CD1-CZ 4.47Å; I104-M218 HydrophobicContact CB-SD 4.46Å; I104-M218 HydrophobicContact CD1-CE 4.21Å; I104-M218 HydrophobicContact CD1-SD 3.81Å; I104-M218 HydrophobicContact CG2-CE 4.41Å; I104-M218 HydrophobicContact CG2-SD 3.76Å
105H98.6Very high96.1Very high0 Ų025 Ų250%013%0.127CC..EExtended strand (participates in β ladder)trans-100.9115.3176-165177.3000110.5F76 D78 G107 Y124 Y137 M138 V139F76-H105 AromaticContact CD2-CD2 3.79Å; F76-H105 HydrophobicContact CE2-CB 4.15Å; F76-H105 AromaticContact CE2-CD2 3.77Å; F76-H105 AromaticContact CE2-CG 3.74Å; F76-H105 CarbonylContact O-C 3.59Å; F76-H105 VanDerWaalsContact O-CA 3.23Å; F76-H105 WeakPolarHBondContact O-CA 3.27Å; F76-H105 PolarHBondContact O-CD2 3.04Å; F76-H105 VanDerWaalsContact O-CD2 3.32Å; D78-H105 PolarHBondContact N-NE2 3.36Å; H105-G107 VanDerWaalsContact C-N 3.32Å; H105-G107 PolarHBondContact NE2-O 2.95Å; H105-G107 PolarHBondContact O-N 2.95Å; H105-Y124 PolarHBondContact CE1-OH 3.19Å; H105-Y124 PolarHBondContact ND1-OH 2.92Å; H105-Y137 HydrophobicContact CB-CE2 3.76Å; H105-Y137 WeakPolarHBondContact CB-OH 3.12Å; H105-Y137 AromaticContact ND1-CZ 3.82Å; H105-Y137 PolarHBondContact ND1-OH 3.45Å; H105-M138 PolarHBondContact N-O 2.97Å; H105-V139 HydrophobicContact CB-CB 4.46Å; H105-V139 HydrophobicContact CB-CG1 3.94Å; H105-V139 WeakPolarHBondContact O-CA 3.27Å
106I97.9Very high95.9Very high0 Ų029.4 Ų29.40%015%0.15CC..  trans-9247.4-171.868.5-169.1000113.8I75 F76 G77 I104 F140 M218 H220 Y265 T302I75-I106 HydrophobicContact CG2-CG2 3.85Å; F76-I106 WeakPolarHBondContact O-CG1 3.37Å; F76-I106 PolarHBondContact O-N 2.75Å; G77-I106 VanDerWaalsContact CA-CG1 3.43Å; I104-I106 HydrophobicContact CG2-CG2 4.3Å; I106-F140 HydrophobicContact CB-CE1 4.1Å; I106-F140 HydrophobicContact CB-CE2 3.95Å; I106-F140 HydrophobicContact CB-CZ 3.38Å; I106-F140 HydrophobicContact CG2-CE1 3.82Å; I106-F140 HydrophobicContact CG2-CZ 3.53Å; I106-M218 HydrophobicContact CG2-CB 4.08Å; I106-M218 HydrophobicContact CG2-CG 4.38Å; I106-H220 PolarHBondContact O-ND1 3.5Å; I106-Y265 WeakPolarHBondContact CD1-O 3.5Å; I106-T302 HydrophobicContact CD1-CG2 3.37Å
107G97.2Very high95.7Very high0 Ų026.9 Ų26.90%014%0.138CC..SBendtrans86.8171.517600000115D78 H105 F140D78-G107 PolarHBondContact N-O 3.09Å; H105-G107 VanDerWaalsContact C-N 3.32Å; H105-G107 PolarHBondContact NE2-O 2.95Å; H105-G107 PolarHBondContact O-N 2.95Å; G107-F140 WeakPolarHBondContact CA-O 3.4Å; G107-F140 PolarHBondContact N-O 3.34Å
108D97.2Very high95.6Very high1 Ų121.7 Ų21.71%0.00511%0.111CC..  trans58.664.4-172.1-74.70.2000112.2L79 Y111 N143 H144 E145 H220L79-D108 PolarHBondContact N-O 2.97Å; D108-Y111 HydrophobicContact CB-CE1 4.35Å; D108-N143 PolarHBondContact OD1-N 2.72Å; D108-N143 PolarHBondContact OD1-OD1 2.92Å; D108-N143 PolarHBondContact OD2-OD1 3.3Å; D108-H144 HydrophobicContact CB-CB 4.45Å; D108-H144 VanDerWaalsContact CG-CD2 3.43Å; D108-H144 WeakPolarHBondContact OD1-CB 3.41Å; D108-H144 IonicContact OD1-CD2 2.62Å; D108-H144 PolarHBondContact OD1-CD2 3.35Å; D108-H144 IonicContact OD1-CG 3.31Å; D108-H144 PolarHBondContact OD1-N 3.18Å; D108-H144 IonicContact OD2-CD2 2.97Å; D108-H144 PolarHBondContact OD2-CD2 2.85Å; D108-H144 VanDerWaalsContact OD2-CD2 3.31Å; D108-E145 PolarHBondContact N-OE2 3.24Å; D108-H220 IonicContact OD1-CE1 3.01Å; D108-H220 IonicContact OD1-NE2 2.95Å; D108-H220 PolarHBondContact OD1-NE2 2.88Å; D108-H220 IonicContact OD2-CE1 3.27Å; D108-H220 PolarHBondContact OD2-CE1 3.32Å; D108-H220 VanDerWaalsContact OD2-CE1 3.31Å; D108-H220 IonicContact OD2-NE2 3.48Å; D108-H220 PolarHBondContact OD2-NE2 3.41Å; D108-H220 VanDerWaalsContact OD2-NE2 3.11Å
109I96.6Very high95.6Very high0 Ų021.2 Ų21.20%011%0.108CC..BIsolated β-bridgetrans-87.4121.8-175.5-48.9177.6000108.9Y111 L113 Y124 V139 E145 I153 F157I109-Y111 PolarHBondContact O-N 2.93Å; I109-L113 HydrophobicContact CB-CD1 4.25Å; I109-L113 HydrophobicContact CB-CG 4.42Å; I109-L113 HydrophobicContact CG2-CD1 4.29Å; I109-L113 HydrophobicContact CG2-CD2 4.07Å; I109-L113 HydrophobicContact CG2-CG 4.39Å; I109-Y124 HydrophobicContact CG2-CD1 3.74Å; I109-Y124 HydrophobicContact CG2-CE1 3.22Å; I109-Y124 HydrophobicContact CG2-CE2 4.34Å; I109-Y124 HydrophobicContact CG2-CG 4.47Å; I109-V139 HydrophobicContact CD1-CB 3.82Å; I109-V139 HydrophobicContact CD1-CG1 4.21Å; I109-V139 HydrophobicContact CD1-CG2 4.01Å; I109-E145 WeakPolarHBondContact CA-OE1 3.39Å; I109-E145 VanDerWaalsContact CB-OE1 3.32Å; I109-E145 WeakPolarHBondContact CB-OE1 3.47Å; I109-E145 PolarHBondContact N-OE1 3.01Å; I109-E145 PolarHBondContact N-OE2 3.34Å; I109-I153 HydrophobicContact CD1-CD1 4.12Å; I109-F157 HydrophobicContact CD1-CE2 4.23Å; I109-F157 HydrophobicContact CD1-CZ 4.29Å; I109-F157 HydrophobicContact CG2-CZ 4.18Å
110A95.3Very high95.6Very high5 Ų521.4 Ų21.44%0.04111%0.106CC..THydrogen-bonded Turntrans65.5-11.6-179.600000115.9L79 L113 R120 Y124L79-A110 WeakPolarHBondContact O-CA 3.2Å; L79-A110 PolarHBondContact O-N 3.26Å; A110-L113 HydrophobicContact CB-CD2 3.71Å; A110-L113 HydrophobicContact CB-CG 4.33Å; A110-R120 HydrophobicContact CB-CG 4.22Å; A110-Y124 HydrophobicContact CB-CD1 4.37Å; A110-Y124 HydrophobicContact CB-CD2 3.33Å; A110-Y124 HydrophobicContact CB-CE2 4.04Å; A110-Y124 HydrophobicContact CB-CG 3.52Å
111Y93.8Very high95.5Very high8 Ų821.2 Ų21.23%0.03111%0.105CC..THydrogen-bonded Turntrans56.482.4-161.6-65.4-90.2000109.8D78 D108 I109 R120 H144 H269 C307 H308D78-Y111 VanDerWaalsContact C-OH 3.31Å; D78-Y111 WeakPolarHBondContact CA-OH 3.27Å; D78-Y111 WeakPolarHBondContact CB-OH 3.47Å; D78-Y111 PolarHBondContact O-OH 3.34Å; D78-Y111 PolarHBondContact OD1-OH 3.33Å; D108-Y111 HydrophobicContact CB-CE1 4.35Å; I109-Y111 PolarHBondContact O-N 2.93Å; Y111-R120 VanDerWaalsContact O-CD 3.23Å; Y111-R120 WeakPolarHBondContact O-CD 3.41Å; Y111-R120 PolarHBondContact O-NH1 3.01Å; Y111-H144 AromaticContact CD1-CD2 3.68Å; Y111-H144 AromaticContact CD1-CE1 3.72Å; Y111-H144 AromaticContact CD1-NE2 3.48Å; Y111-H144 WeakPolarHBondContact CD1-NE2 3.37Å; Y111-H144 AromaticContact CE1-CD2 3.99Å; Y111-H144 AromaticContact CE1-NE2 3.9Å; Y111-H269 AromaticContact CE1-NE2 3.98Å; Y111-H269 PolarHBondContact OH-NE2 3.01Å; Y111-C307 HydrophobicContact CE1-CB 4.29Å; Y111-C307 WeakPolarHBondContact CE1-SG 3.26Å; Y111-C307 HydrophobicContact CE2-CB 3.94Å; Y111-C307 WeakPolarHBondContact OH-CB 3.3Å; Y111-C307 PolarHBondContact OH-SG 3.44Å; Y111-H308 AromaticContact CD1-CE1 3.39Å; Y111-H308 WeakPolarHBondContact CD1-CE1 3.38Å; Y111-H308 AromaticContact CD1-ND1 3.11Å; Y111-H308 WeakPolarHBondContact CD1-ND1 3.47Å; Y111-H308 AromaticContact CE1-CE1 3.59Å; Y111-H308 AromaticContact CE1-ND1 3.41Å; Y111-H308 WeakPolarHBondContact CE1-ND1 3.12Å; Y111-H308 AromaticContact CG-ND1 3.59Å
112D94.1Very high95.5Very high22 Ų2222.9 Ų22.912%0.11811%0.114CC..THydrogen-bonded Turntrans77.378.4178.4-50-50.1000114.1H114 D115 R120 H144D112-H114 PolarHBondContact O-N 3.26Å; D112-H114 IonicContact OD1-CE1 2.71Å; D112-D115 HydrophobicContact CB-CB 4.22Å; D112-D115 WeakPolarHBondContact O-CB 3.39Å; D112-D115 PolarHBondContact O-N 3.21Å; D112-R120 WeakPolarHBondContact O-CD 3.47Å; D112-H144 IonicContact OD1-CE1 3.36Å; D112-H144 IonicContact OD1-CG 3.91Å; D112-H144 IonicContact OD1-ND1 3.06Å; D112-H144 PolarHBondContact OD1-ND1 2.84Å; D112-H144 IonicContact OD2-CE1 2.74Å; D112-H144 PolarHBondContact OD2-CE1 3.08Å; D112-H144 IonicContact OD2-ND1 2.65Å; D112-H144 PolarHBondContact OD2-ND1 3.31Å
113L94.8Very high95.5Very high3 Ų327.6 Ų27.62%0.01614%0.139CC..THydrogen-bonded Turntrans-53.1-21.7173.7-70169.3000114.2I109 A110 G118 G121 Y124 E145 Q152 F157I109-L113 HydrophobicContact CB-CD1 4.25Å; I109-L113 HydrophobicContact CB-CG 4.42Å; I109-L113 HydrophobicContact CG2-CD1 4.29Å; I109-L113 HydrophobicContact CG2-CD2 4.07Å; I109-L113 HydrophobicContact CG2-CG 4.39Å; A110-L113 HydrophobicContact CB-CD2 3.71Å; A110-L113 HydrophobicContact CB-CG 4.33Å; L113-G118 WeakPolarHBondContact O-CA 3.31Å; L113-G121 PolarHBondContact O-N 3.07Å; L113-Y124 HydrophobicContact CD2-CD1 4.38Å; L113-Y124 HydrophobicContact CD2-CG 4.47Å; L113-E145 HydrophobicContact CD1-CG 4.47Å; L113-Q152 HydrophobicContact CB-CB 3.5Å; L113-Q152 HydrophobicContact CB-CG 3.73Å; L113-Q152 HydrophobicContact CD1-CB 3.86Å; L113-Q152 HydrophobicContact CG-CB 4.35Å; L113-F157 HydrophobicContact CD1-CE2 3.97Å
114H93.9Very high95.4Very high44 Ų4427.6 Ų27.620%0.20414%0.139CC..THydrogen-bonded Turntrans-88.1-12.4-176.969.8-82.2000113.6D112 G118 D147 Q152D112-H114 PolarHBondContact O-N 3.26Å; D112-H114 IonicContact OD1-CE1 2.71Å; H114-G118 PolarHBondContact O-N 3.31Å; H114-D147 VanDerWaalsContact CE1-CB 3.46Å; H114-D147 WeakPolarHBondContact CE1-CB 3.49Å; H114-Q152 HydrophobicContact CB-CG 3.76Å
115D93.9Very high95.4Very high48 Ų4830.4 Ų30.426%0.25715%0.153SC..G310 helixtrans-61.3154.9177.7-89.16.4000111.9D112 E117 G118 N119 R120D112-D115 HydrophobicContact CB-CB 4.22Å; D112-D115 WeakPolarHBondContact O-CB 3.39Å; D112-D115 PolarHBondContact O-N 3.21Å; D115-E117 PolarHBondContact O-N 3.19Å; D115-G118 PolarHBondContact O-N 3.43Å; D115-N119 PolarHBondContact O-N 3.33Å; D115-R120 HydrophobicContact CB-CB 4.12Å; D115-R120 PolarHBondContact O-N 3.45Å; D115-R120 IonicContact OD2-CZ 2.79Å; D115-R120 IonicContact OD2-NE 3.52Å; D115-R120 IonicContact OD2-NH1 2.74Å; D115-R120 PolarHBondContact OD2-NH1 3.11Å; D115-R120 IonicContact OD2-NH2 3.36Å; D115-R120 PolarHBondContact OD2-NH2 3Å
116D93.3Very high95.4Very high103 Ų10335.3 Ų35.355%0.55118%0.179SC*.G310 helixtrans54.438.8-177.9-54.2-56.7000111.3G118 N119 R120D116-G118 VanDerWaalsContact C-N 3.26Å; D116-G118 PolarHBondContact O-N 2.88Å; D116-N119 HydrophobicContact CB-CB 4.12Å; D116-N119 VanDerWaalsContact O-CB 3.23Å; D116-N119 WeakPolarHBondContact O-CB 3.19Å; D116-N119 PolarHBondContact O-N 3.45Å; D116-N119 VanDerWaalsContact O-N 3.1Å; D116-N119 PolarHBondContact O-ND2 3.29Å; D116-N119 VanDerWaalsContact O-ND2 3.07Å; D116-R120 IonicContact OD2-NE 3.75Å; D116-R120 IonicContact OD2-NH2 3.9Å; D116-R120 PolarHBondContact OD2-NH2 3.41Å
117E90.9Very high95.4Very high47 Ų4736.4 Ų36.422%0.2219%0.188CC..G310 helixtrans58.837.8-178.6-53.1177.9-157.400112.9H26 Y28 R30 D115 N119H26-E117 VanDerWaalsContact CB-OE2 3.3Å; H26-E117 WeakPolarHBondContact CB-OE2 3.35Å; H26-E117 IonicContact CE1-OE1 3.21Å; H26-E117 PolarHBondContact CE1-OE1 3.01Å; H26-E117 IonicContact CE1-OE2 3.92Å; H26-E117 IonicContact CG-OE1 3.31Å; H26-E117 IonicContact CG-OE2 3.11Å; H26-E117 IonicContact ND1-OE1 2.68Å; H26-E117 PolarHBondContact ND1-OE1 3.35Å; H26-E117 IonicContact ND1-OE2 2.8Å; H26-E117 PolarHBondContact ND1-OE2 3.41Å; Y28-E117 HydrophobicContact CD2-CB 3.97Å; Y28-E117 HydrophobicContact CE2-CB 4Å; Y28-E117 WeakPolarHBondContact CE2-OE2 2.97Å; R30-E117 PolarHBondContact NH1-O 3.19Å; R30-E117 PolarHBondContact NH2-O 2.85Å; D115-E117 PolarHBondContact O-N 3.19Å; E117-N119 VanDerWaalsContact C-N 3.33Å
118G92.8Very high95.4Very high0 Ų036.4 Ų36.40%019%0.188CC..G310 helixtrans84.9-2.8-178.500000114.7D22 R30 L113 H114 D115 D116 R120 G121 D122 R156D22-G118 WeakPolarHBondContact OD2-CA 3.48Å; R30-G118 VanDerWaalsContact NH2-C 3.35Å; L113-G118 WeakPolarHBondContact O-CA 3.31Å; H114-G118 PolarHBondContact O-N 3.31Å; D115-G118 PolarHBondContact O-N 3.43Å; D116-G118 VanDerWaalsContact C-N 3.26Å; D116-G118 PolarHBondContact O-N 2.88Å; G118-R120 VanDerWaalsContact C-N 3.26Å; G118-R120 PolarHBondContact O-N 2.78Å; G118-G121 PolarHBondContact O-N 2.81Å; G118-G121 VanDerWaalsContact O-N 3.1Å; G118-D122 PolarHBondContact O-N 2.96Å; G118-D122 VanDerWaalsContact O-N 3.12Å; G118-R156 PolarHBondContact O-NH2 2.92Å
119N94.1Very high95.5Very high78 Ų7840.3 Ų40.342%0.41721%0.207SC..Hα-helixtrans-64.8-32.5178.4-68.7-26.8000111.5R30 D115 D116 E117 G121 D122 D123R30-N119 PolarHBondContact NH2-OD1 3.03Å; D115-N119 PolarHBondContact O-N 3.33Å; D116-N119 HydrophobicContact CB-CB 4.12Å; D116-N119 VanDerWaalsContact O-CB 3.23Å; D116-N119 WeakPolarHBondContact O-CB 3.19Å; D116-N119 PolarHBondContact O-N 3.45Å; D116-N119 VanDerWaalsContact O-N 3.1Å; D116-N119 PolarHBondContact O-ND2 3.29Å; D116-N119 VanDerWaalsContact O-ND2 3.07Å; E117-N119 VanDerWaalsContact C-N 3.33Å; N119-G121 VanDerWaalsContact C-N 3.25Å; N119-G121 PolarHBondContact O-N 2.97Å; N119-D122 WeakPolarHBondContact O-CB 3.28Å; N119-D122 PolarHBondContact O-N 2.84Å; N119-D123 PolarHBondContact O-N 2.85Å
120R94.9Very high95.6Very high71 Ų7142.5 Ų42.527%0.26822%0.221SC..Hα-helixtrans-58.5-41.2172.3-174.8170.2-58.3165.915.1111.7A110 Y111 D112 D115 D116 G118 D122 D123 Y124A110-R120 HydrophobicContact CB-CG 4.22Å; Y111-R120 VanDerWaalsContact O-CD 3.23Å; Y111-R120 WeakPolarHBondContact O-CD 3.41Å; Y111-R120 PolarHBondContact O-NH1 3.01Å; D112-R120 WeakPolarHBondContact O-CD 3.47Å; D115-R120 HydrophobicContact CB-CB 4.12Å; D115-R120 PolarHBondContact O-N 3.45Å; D115-R120 IonicContact OD2-CZ 2.79Å; D115-R120 IonicContact OD2-NE 3.52Å; D115-R120 IonicContact OD2-NH1 2.74Å; D115-R120 PolarHBondContact OD2-NH1 3.11Å; D115-R120 IonicContact OD2-NH2 3.36Å; D115-R120 PolarHBondContact OD2-NH2 3Å; D116-R120 IonicContact OD2-NE 3.75Å; D116-R120 IonicContact OD2-NH2 3.9Å; D116-R120 PolarHBondContact OD2-NH2 3.41Å; G118-R120 VanDerWaalsContact C-N 3.26Å; G118-R120 PolarHBondContact O-N 2.78Å; R120-D122 VanDerWaalsContact C-N 3.34Å; R120-D123 PolarHBondContact O-N 2.74Å; R120-Y124 WeakPolarHBondContact O-CB 3.1Å; R120-Y124 PolarHBondContact O-N 3.47Å
121G95.2Very high95.7Very high0 Ų042.2 Ų42.20%022%0.219CC..Hα-helixtrans-63.9-37.8173.400000112.9L113 G118 N119 Y124 M125L113-G121 PolarHBondContact O-N 3.07Å; G118-G121 PolarHBondContact O-N 2.81Å; G118-G121 VanDerWaalsContact O-N 3.1Å; N119-G121 VanDerWaalsContact C-N 3.25Å; N119-G121 PolarHBondContact O-N 2.97Å; G121-Y124 PolarHBondContact O-N 2.9Å; G121-M125 VanDerWaalsContact O-CG 3.26Å; G121-M125 WeakPolarHBondContact O-CG 3.38Å; G121-M125 PolarHBondContact O-N 2.8Å
122D95.8Very high95.9Very high50 Ų5043.3 Ų43.327%0.26723%0.23SC..Hα-helixtrans-66.4-46.4176.9-61.3-32.5000111.2R30 G118 N119 R120 Y124 M125 N126 R156R30-D122 IonicContact CZ-OD2 3Å; R30-D122 IonicContact NE-OD1 2.77Å; R30-D122 IonicContact NE-OD2 3.35Å; R30-D122 PolarHBondContact NE-OD2 2.84Å; R30-D122 VanDerWaalsContact NE-OD2 3.12Å; R30-D122 IonicContact NH2-OD2 3.35Å; R30-D122 PolarHBondContact NH2-OD2 2.78Å; G118-D122 PolarHBondContact O-N 2.96Å; G118-D122 VanDerWaalsContact O-N 3.12Å; N119-D122 WeakPolarHBondContact O-CB 3.28Å; N119-D122 PolarHBondContact O-N 2.84Å; R120-D122 VanDerWaalsContact C-N 3.34Å; D122-Y124 VanDerWaalsContact C-N 3.33Å; D122-Y124 PolarHBondContact O-N 2.89Å; D122-M125 PolarHBondContact O-N 2.8Å; D122-N126 PolarHBondContact O-N 2.9Å; D122-N126 VanDerWaalsContact O-N 3.11Å; D122-N126 PolarHBondContact O-ND2 3.07Å; D122-R156 IonicContact OD1-CZ 3.69Å; D122-R156 VanDerWaalsContact OD1-CZ 3.23Å; D122-R156 IonicContact OD1-NH1 3.57Å; D122-R156 PolarHBondContact OD1-NH1 2.91Å; D122-R156 IonicContact OD1-NH2 2.95Å; D122-R156 PolarHBondContact OD1-NH2 3.03Å; D122-R156 IonicContact OD2-NH2 3.62Å
123D97.3Very high96.1Very high100 Ų10042.8 Ų42.854%0.53523%0.228SC..Hα-helixtrans-61-41175.1-72.6-19.2000112.1N119 R120 N126 A127N119-D123 PolarHBondContact O-N 2.85Å; R120-D123 PolarHBondContact O-N 2.74Å; D123-N126 PolarHBondContact O-N 2.83Å; D123-A127 WeakPolarHBondContact O-CB 3.23Å; D123-A127 PolarHBondContact O-N 2.85Å
124Y97.8Very high96.3Very high0 Ų045.2 Ų45.20%024%0.238CC..Hα-helixtrans-63.1-46176.9-172.3-92.4000112.1L79 V81 H105 I109 A110 L113 R120 G121 D122 N126 A127 V128 Y137L79-Y124 HydrophobicContact CG-CE2 4.45Å; L79-Y124 VanDerWaalsContact O-CE2 3.26Å; L79-Y124 WeakPolarHBondContact O-CE2 3.4Å; V81-Y124 HydrophobicContact CG2-CD2 3.68Å; V81-Y124 HydrophobicContact CG2-CG 4.35Å; H105-Y124 PolarHBondContact CE1-OH 3.19Å; H105-Y124 PolarHBondContact ND1-OH 2.92Å; I109-Y124 HydrophobicContact CG2-CD1 3.74Å; I109-Y124 HydrophobicContact CG2-CE1 3.22Å; I109-Y124 HydrophobicContact CG2-CE2 4.34Å; I109-Y124 HydrophobicContact CG2-CG 4.47Å; A110-Y124 HydrophobicContact CB-CD1 4.37Å; A110-Y124 HydrophobicContact CB-CD2 3.33Å; A110-Y124 HydrophobicContact CB-CE2 4.04Å; A110-Y124 HydrophobicContact CB-CG 3.52Å; L113-Y124 HydrophobicContact CD2-CD1 4.38Å; L113-Y124 HydrophobicContact CD2-CG 4.47Å; R120-Y124 WeakPolarHBondContact O-CB 3.1Å; R120-Y124 PolarHBondContact O-N 3.47Å; G121-Y124 PolarHBondContact O-N 2.9Å; D122-Y124 VanDerWaalsContact C-N 3.33Å; D122-Y124 PolarHBondContact O-N 2.89Å; Y124-N126 VanDerWaalsContact C-N 3.26Å; Y124-N126 PolarHBondContact O-N 3.2Å; Y124-A127 WeakPolarHBondContact O-CB 3.4Å; Y124-A127 PolarHBondContact O-N 2.59Å; Y124-V128 HydrophobicContact CD1-CG1 4.12Å; Y124-V128 HydrophobicContact CD1-CG2 4.37Å; Y124-V128 HydrophobicContact CE1-CG1 3.56Å; Y124-V128 HydrophobicContact CE1-CG2 4.22Å; Y124-V128 HydrophobicContact CE2-CG1 4.2Å; Y124-V128 WeakPolarHBondContact O-CG2 3.49Å; Y124-V128 PolarHBondContact O-N 2.97Å; Y124-Y137 PolarHBondContact OH-OH 2.52Å
125M97.9Very high96.4Very high58 Ų5843.6 Ų43.629%0.28623%0.231SC..Hα-helixtrans-61-37.3178-67.3-50.4-6500111.7G121 D122 Q129 F157G121-M125 VanDerWaalsContact O-CG 3.26Å; G121-M125 WeakPolarHBondContact O-CG 3.38Å; G121-M125 PolarHBondContact O-N 2.8Å; D122-M125 PolarHBondContact O-N 2.8Å; M125-Q129 PolarHBondContact O-N 2.92Å; M125-Q129 VanDerWaalsContact O-N 3.1Å; M125-F157 HydrophobicContact CE-CE1 4.01Å; M125-F157 HydrophobicContact CE-CZ 4.42Å; M125-F157 HydrophobicContact SD-CE1 3.73Å; M125-F157 HydrophobicContact SD-CE2 4.39Å; M125-F157 HydrophobicContact SD-CZ 3.57Å; M125-F157 VanDerWaalsContact SD-CZ 3.57Å
126N98.2Very high96.6Very high103 Ų10343.6 Ų43.655%0.55123%0.233SC*.Hα-helixtrans-65.1-41.4172.9-68.7-33.5000111.9D122 D123 Y124 V128D122-N126 PolarHBondContact O-N 2.9Å; D122-N126 VanDerWaalsContact O-N 3.11Å; D122-N126 PolarHBondContact O-ND2 3.07Å; D123-N126 PolarHBondContact O-N 2.83Å; Y124-N126 VanDerWaalsContact C-N 3.26Å; Y124-N126 PolarHBondContact O-N 3.2Å; N126-V128 PolarHBondContact O-N 2.76Å
127A98.3Very high96.8Very high23 Ų2339.9 Ų39.919%0.1921%0.212CC..Hα-helixtrans-66.2-34.7-178.900000113.1V81 I88 D123 Y124 P130V81-A127 HydrophobicContact CG1-CB 3.99Å; V81-A127 HydrophobicContact CG2-CB 4.24Å; I88-A127 HydrophobicContact CD1-CB 4.17Å; I88-A127 VanDerWaalsContact CG2-O 3.29Å; I88-A127 WeakPolarHBondContact CG2-O 3.47Å; D123-A127 WeakPolarHBondContact O-CB 3.23Å; D123-A127 PolarHBondContact O-N 2.85Å; Y124-A127 WeakPolarHBondContact O-CB 3.4Å; Y124-A127 PolarHBondContact O-N 2.59Å; A127-P130 WeakPolarHBondContact O-CD 3.47Å
128V98.3Very high97.2Very high0 Ų038.7 Ų38.70%021%0.206CC..Hα-helixtrans-91.8-15.2-179.2-57.30000114.3Y124 N126 P130 F131 A132 Y137Y124-V128 HydrophobicContact CD1-CG1 4.12Å; Y124-V128 HydrophobicContact CD1-CG2 4.37Å; Y124-V128 HydrophobicContact CE1-CG1 3.56Å; Y124-V128 HydrophobicContact CE1-CG2 4.22Å; Y124-V128 HydrophobicContact CE2-CG1 4.2Å; Y124-V128 WeakPolarHBondContact O-CG2 3.49Å; Y124-V128 PolarHBondContact O-N 2.97Å; N126-V128 PolarHBondContact O-N 2.76Å; V128-P130 VanDerWaalsContact C-N 3.28Å; V128-P130 VanDerWaalsContact O-N 3.16Å; V128-F131 HydrophobicContact CB-CE1 3.78Å; V128-F131 HydrophobicContact CB-CE2 3.88Å; V128-F131 HydrophobicContact CB-CZ 3.36Å; V128-F131 HydrophobicContact CG1-CE1 3.96Å; V128-F131 HydrophobicContact CG1-CE2 4.38Å; V128-F131 HydrophobicContact CG1-CZ 3.5Å; V128-F131 VanDerWaalsContact CG1-CZ 3.5Å; V128-F131 WeakPolarHBondContact O-CG 3.22Å; V128-F131 PolarHBondContact O-N 2.94Å; V128-F131 VanDerWaalsContact O-N 3.13Å; V128-A132 HydrophobicContact CG2-CB 4.33Å; V128-A132 WeakPolarHBondContact O-CB 3.24Å; V128-A132 PolarHBondContact O-N 2.9Å; V128-Y137 HydrophobicContact CG2-CE1 4.44Å
129Q98.4Very high97.4Very high83 Ų8338.7 Ų38.739%0.38821%0.206SC..Hα-helixtrans-47.1-41.9178-178.3-173.53900114.1Y60 M125 F131 A132 A133Y60-Q129 PolarHBondContact OH-NE2 2.94Å; M125-Q129 PolarHBondContact O-N 2.92Å; M125-Q129 VanDerWaalsContact O-N 3.1Å; Q129-F131 PolarHBondContact O-N 3.09Å; Q129-F131 VanDerWaalsContact O-N 3.09Å; Q129-A132 PolarHBondContact O-N 2.77Å; Q129-A133 HydrophobicContact CG-CB 4.35Å; Q129-A133 VanDerWaalsContact O-CB 3.27Å; Q129-A133 WeakPolarHBondContact O-CB 3.42Å; Q129-A133 PolarHBondContact O-N 3Å
130P98.3Very high97.5Very high46 Ų4635 Ų3530%0.29919%0.187SC..Hα-helixtrans-57.9-25.2-177.6-27.737.5000115T92 H96 A127 V128 Y134T92-P130 HydrophobicContact CG2-CB 3.53Å; H96-P130 PolarHBondContact CE1-O 3.43Å; H96-P130 PolarHBondContact NE2-O 2.7Å; A127-P130 WeakPolarHBondContact O-CD 3.47Å; V128-P130 VanDerWaalsContact C-N 3.28Å; V128-P130 VanDerWaalsContact O-N 3.16Å; P130-Y134 WeakPolarHBondContact O-CD2 3.33Å; P130-Y134 WeakPolarHBondContact O-CE2 3.42Å
131F98.1Very high97.6Very high0 Ų031.6 Ų31.60%017%0.174CC..Hα-helixtrans-107.3-37.4171.261.4-102.2000113.1I88 L91 T95 I103 V128 Q129 A133 Y134 V135 Y137I88-F131 HydrophobicContact CG2-CE1 4.3Å; L91-F131 HydrophobicContact CB-CD1 4.09Å; L91-F131 HydrophobicContact CB-CE1 4.32Å; L91-F131 HydrophobicContact CB-CG 4.48Å; L91-F131 HydrophobicContact CD1-CE1 4.44Å; L91-F131 HydrophobicContact CD1-CZ 4.5Å; T95-F131 HydrophobicContact CG2-CB 4.08Å; T95-F131 WeakPolarHBondContact OG1-CB 3.45Å; I103-F131 HydrophobicContact CD1-CB 4.17Å; I103-F131 HydrophobicContact CD1-CD2 3.61Å; I103-F131 HydrophobicContact CD1-CE2 4.34Å; I103-F131 HydrophobicContact CD1-CG 4.2Å; V128-F131 HydrophobicContact CB-CE1 3.78Å; V128-F131 HydrophobicContact CB-CE2 3.88Å; V128-F131 HydrophobicContact CB-CZ 3.36Å; V128-F131 HydrophobicContact CG1-CE1 3.96Å; V128-F131 HydrophobicContact CG1-CE2 4.38Å; V128-F131 HydrophobicContact CG1-CZ 3.5Å; V128-F131 VanDerWaalsContact CG1-CZ 3.5Å; V128-F131 WeakPolarHBondContact O-CG 3.22Å; V128-F131 PolarHBondContact O-N 2.94Å; V128-F131 VanDerWaalsContact O-N 3.13Å; Q129-F131 PolarHBondContact O-N 3.09Å; Q129-F131 VanDerWaalsContact O-N 3.09Å; F131-A133 PolarHBondContact O-N 2.92Å; F131-Y134 PolarHBondContact O-N 2.77Å; F131-V135 PolarHBondContact O-N 3.14Å; F131-Y137 AromaticContact CE2-CD2 3.96Å; F131-Y137 HydrophobicContact CE2-CD2 3.96Å; F131-Y137 AromaticContact CE2-CE2 3.86Å; F131-Y137 HydrophobicContact CE2-CE2 3.86Å; F131-Y137 HydrophobicContact CE2-CG 4.46Å
132A98.2Very high97.7Very high31 Ų3131.6 Ų31.626%0.25617%0.174SC..Hα-helixtrans-70.1-19.2-174.700000113.5V128 Q129 Y134 Y137V128-A132 HydrophobicContact CG2-CB 4.33Å; V128-A132 WeakPolarHBondContact O-CB 3.24Å; V128-A132 PolarHBondContact O-N 2.9Å; Q129-A132 PolarHBondContact O-N 2.77Å; A132-Y134 VanDerWaalsContact C-N 3.29Å; A132-Y137 HydrophobicContact CB-CD1 4.21Å; A132-Y137 HydrophobicContact CB-CG 4.16Å
133A97.9Very high97.7Very high11 Ų1130.5 Ų30.59%0.09117%0.168CC..THydrogen-bonded Turntrans-79.7-9.4171.800000113.6Y48 Y60 Q129 F131Y48-A133 WeakPolarHBondContact OH-CA 3.49Å; Y48-A133 PolarHBondContact OH-O 3.47Å; Y60-A133 HydrophobicContact CD1-CB 3.57Å; Y60-A133 HydrophobicContact CE1-CB 3.95Å; Y60-A133 HydrophobicContact CG-CB 3.93Å; Q129-A133 HydrophobicContact CG-CB 4.35Å; Q129-A133 VanDerWaalsContact O-CB 3.27Å; Q129-A133 WeakPolarHBondContact O-CB 3.42Å; Q129-A133 PolarHBondContact O-N 3Å; F131-A133 PolarHBondContact O-N 2.92Å
134Y98.1Very high97.6Very high54 Ų5427.2 Ų27.221%0.21215%0.149CC..THydrogen-bonded Turntrans-119.7-24.9-173.5-60.9-91.1000114Y60 H61 F62 H96 P130 F131 A132Y60-Y134 HydrophobicContact CD1-CE1 4.32Å; Y60-Y134 AromaticContact CD1-CE2 3.92Å; Y60-Y134 HydrophobicContact CD1-CE2 3.92Å; Y60-Y134 AromaticContact CD1-CZ 3.69Å; Y60-Y134 HydrophobicContact CE1-CE2 4.39Å; H61-Y134 AromaticContact CE1-CD1 3.54Å; H61-Y134 AromaticContact CE1-CE1 3.65Å; H61-Y134 AromaticContact ND1-CD1 3.63Å; H61-Y134 AromaticContact ND1-CE1 3.57Å; H61-Y134 VanDerWaalsContact O-CA 3.25Å; H61-Y134 WeakPolarHBondContact O-CA 3.46Å; H61-Y134 VanDerWaalsContact O-CD1 3.23Å; H61-Y134 WeakPolarHBondContact O-CD1 3.47Å; F62-Y134 WeakPolarHBondContact CA-O 3.45Å; F62-Y134 VanDerWaalsContact CB-O 3.23Å; F62-Y134 WeakPolarHBondContact CB-O 3.34Å; H96-Y134 AromaticContact CE1-CD2 3.87Å; H96-Y134 AromaticContact CE1-CE2 3.69Å; H96-Y134 AromaticContact CE1-CZ 3.98Å; P130-Y134 WeakPolarHBondContact O-CD2 3.33Å; P130-Y134 WeakPolarHBondContact O-CE2 3.42Å; F131-Y134 PolarHBondContact O-N 2.77Å; A132-Y134 VanDerWaalsContact C-N 3.29Å
135V97.8Very high97.6Very high10 Ų1027.3 Ų27.36%0.06115%0.15CC..SBendtrans-130136.1177.2176.90000108.7T95 F100 I103 F131 Y137T95-V135 HydrophobicContact CG2-CB 4.4Å; T95-V135 HydrophobicContact CG2-CG2 3.57Å; F100-V135 HydrophobicContact CB-CG1 4.22Å; F100-V135 HydrophobicContact CB-CG2 4.46Å; I103-V135 HydrophobicContact CD1-CB 4.09Å; I103-V135 HydrophobicContact CD1-CG1 4.1Å; I103-V135 HydrophobicContact CG1-CB 4.34Å; I103-V135 HydrophobicContact CG1-CG1 3.79Å; F131-V135 PolarHBondContact O-N 3.14Å; V135-Y137 PolarHBondContact O-N 3.5Å
136P96.8Very high97.4Very high48 Ų4825 Ų2531%0.31214%0.139SC..  trans-50.5123.2174.4-27.734.8000111.9D101 V102 I103D101-P136 WeakPolarHBondContact O-CD 3.4Å; V102-P136 HydrophobicContact CG2-CB 4.47Å; I103-P136 PolarHBondContact N-O 3.17Å
137Y98.1Very high96.7Very high24 Ų2425.1 Ų25.19%0.09414%0.14CC..EExtended strand (participates in β ladder)trans-108.1102.8-177.9-174.6-127.9000110.2F76 I103 H105 Y124 V128 F131 A132 V135 V139 F157 M159F76-Y137 HydrophobicContact CZ-CE2 4.09Å; I103-Y137 HydrophobicContact CB-CD2 4.04Å; I103-Y137 HydrophobicContact CG2-CD2 3.69Å; I103-Y137 HydrophobicContact CG2-CE2 3.87Å; I103-Y137 WeakPolarHBondContact O-CA 3.35Å; H105-Y137 HydrophobicContact CB-CE2 3.76Å; H105-Y137 WeakPolarHBondContact CB-OH 3.12Å; H105-Y137 AromaticContact ND1-CZ 3.82Å; H105-Y137 PolarHBondContact ND1-OH 3.45Å; Y124-Y137 PolarHBondContact OH-OH 2.52Å; V128-Y137 HydrophobicContact CG2-CE1 4.44Å; F131-Y137 AromaticContact CE2-CD2 3.96Å; F131-Y137 HydrophobicContact CE2-CD2 3.96Å; F131-Y137 AromaticContact CE2-CE2 3.86Å; F131-Y137 HydrophobicContact CE2-CE2 3.86Å; F131-Y137 HydrophobicContact CE2-CG 4.46Å; A132-Y137 HydrophobicContact CB-CD1 4.21Å; A132-Y137 HydrophobicContact CB-CG 4.16Å; V135-Y137 PolarHBondContact O-N 3.5Å; Y137-V139 HydrophobicContact CD1-CG1 3.85Å; Y137-V139 HydrophobicContact CE1-CG1 3.57Å; Y137-V139 HydrophobicContact CE2-CG1 4.39Å; Y137-V139 HydrophobicContact CG-CG1 4.38Å; Y137-F157 HydrophobicContact CD1-CE1 4.21Å; Y137-F157 AromaticContact CE1-CE1 3.98Å; Y137-F157 HydrophobicContact CE1-CE1 3.98Å; Y137-M159 WeakPolarHBondContact O-CE 3.18Å
138M98.2Very high96.1Very high22 Ų2224.1 Ų24.111%0.10813%0.131CC..EExtended strand (participates in β ladder)trans-96134-175.8-50.7-59.4-64.900109.4V102 I103 I104 H105 M159 P160 W171 F173V102-M138 HydrophobicContact CG2-CG 3.68Å; I103-M138 PolarHBondContact O-N 2.72Å; I104-M138 CarbonylContact C-O 3.58Å; I104-M138 WeakPolarHBondContact CA-O 3.27Å; I104-M138 HydrophobicContact CG1-CB 4.21Å; I104-M138 HydrophobicContact CG2-CB 4.34Å; H105-M138 PolarHBondContact N-O 2.97Å; M138-M159 HydrophobicContact CB-SD 4.32Å; M138-M159 HydrophobicContact CE-SD 3.85Å; M138-M159 HydrophobicContact SD-SD 4.42Å; M138-P160 VanDerWaalsContact CE-CD 3.46Å; M138-P160 HydrophobicContact CE-CG 3.87Å; M138-W171 HydrophobicContact CB-CH2 3.82Å; M138-W171 HydrophobicContact CB-CZ2 3.88Å; M138-W171 HydrophobicContact CE-CE3 4.38Å; M138-W171 HydrophobicContact CE-CH2 4.21Å; M138-W171 HydrophobicContact CE-CZ2 4.32Å; M138-W171 HydrophobicContact CE-CZ3 4.27Å; M138-F173 HydrophobicContact CB-CE1 4.4Å; M138-F173 HydrophobicContact CE-CD1 3.6Å; M138-F173 HydrophobicContact CE-CE1 3.51Å; M138-F173 HydrophobicContact CE-CG 4.48Å; M138-F173 HydrophobicContact CE-CZ 4.33Å; M138-F173 HydrophobicContact CG-CE1 3.82Å; M138-F173 HydrophobicContact CG-CZ 3.94Å; M138-F173 HydrophobicContact SD-CE1 4.28Å
139V98.1Very high95.8Very high0 Ų031.1 Ų31.10%016%0.164CC..EExtended strand (participates in β ladder)trans-139.1156.8-177.1-46.50000111.3H105 I109 Y137 I153 F157 M159 W171H105-V139 HydrophobicContact CB-CB 4.46Å; H105-V139 HydrophobicContact CB-CG1 3.94Å; H105-V139 WeakPolarHBondContact O-CA 3.27Å; I109-V139 HydrophobicContact CD1-CB 3.82Å; I109-V139 HydrophobicContact CD1-CG1 4.21Å; I109-V139 HydrophobicContact CD1-CG2 4.01Å; Y137-V139 HydrophobicContact CD1-CG1 3.85Å; Y137-V139 HydrophobicContact CE1-CG1 3.57Å; Y137-V139 HydrophobicContact CE2-CG1 4.39Å; Y137-V139 HydrophobicContact CG-CG1 4.38Å; V139-I153 HydrophobicContact CG2-CD1 4.05Å; V139-I153 HydrophobicContact CG2-CG1 4.2Å; V139-F157 HydrophobicContact CG1-CD1 4.06Å; V139-F157 HydrophobicContact CG1-CE1 4.06Å; V139-F157 HydrophobicContact CG2-CB 3.82Å; V139-F157 HydrophobicContact CG2-CD1 3.67Å; V139-F157 HydrophobicContact CG2-CD2 3.98Å; V139-F157 HydrophobicContact CG2-CE1 4.23Å; V139-F157 HydrophobicContact CG2-CE2 4.49Å; V139-F157 HydrophobicContact CG2-CG 3.54Å; V139-M159 HydrophobicContact CB-CE 4.41Å; V139-M159 HydrophobicContact CG2-CE 3.79Å; V139-M159 HydrophobicContact CG2-SD 4.47Å; V139-M159 PolarHBondContact N-SD 3.36Å; V139-M159 WeakPolarHBondContact O-CG 3.29Å; V139-M159 VanDerWaalsContact O-SD 3.34Å; V139-W171 PolarHBondContact O-NE1 3.03Å
140F96.5Very high95.6Very high0 Ų027.8 Ų27.80%015%0.148CC..  trans-145.7172163.854.8-98.6000109I106 G107 I153 W171 M218 F219 H220I106-F140 HydrophobicContact CB-CE1 4.1Å; I106-F140 HydrophobicContact CB-CE2 3.95Å; I106-F140 HydrophobicContact CB-CZ 3.38Å; I106-F140 HydrophobicContact CG2-CE1 3.82Å; I106-F140 HydrophobicContact CG2-CZ 3.53Å; G107-F140 WeakPolarHBondContact CA-O 3.4Å; G107-F140 PolarHBondContact N-O 3.34Å; F140-I153 VanDerWaalsContact C-CD1 3.4Å; F140-W171 HydrophobicContact CD1-CZ2 4.05Å; F140-M218 HydrophobicContact CE1-CB 3.62Å; F140-M218 HydrophobicContact CZ-CB 3.63Å; F140-F219 VanDerWaalsContact CE2-CA 3.49Å; F140-H220 HydrophobicContact CE2-CB 4.39Å
141A97.1Very high95.4Very high0 Ų027.1 Ų27.10%014%0.142CC..  trans-76.8138.1-171.800000112.8E145 F150 I153 L169A141-E145 HydrophobicContact CB-CB 3.82Å; A141-E145 HydrophobicContact CB-CG 4.43Å; A141-F150 HydrophobicContact CB-CD1 3.67Å; A141-F150 HydrophobicContact CB-CE1 3.72Å; A141-I153 HydrophobicContact CB-CD1 4.14Å; A141-L169 HydrophobicContact CB-CD2 3.94Å
142G97Very high95.3Very high0 Ų027.2 Ų27.20%014%0.142CC..  trans-100-165153.300000111.3E145 E186 H220G142-E145 PolarHBondContact N-OE2 2.97Å; G142-E145 PolarHBondContact O-N 3.41Å; G142-E186 WeakPolarHBondContact O-CG 3.36Å; G142-H220 WeakPolarHBondContact CA-CD2 3.19Å
143N95.8Very high95.1Very high28 Ų2825.7 Ų25.715%0.1513%0.13CC..G310 helixtrans-72.8-30-179.760.1-91000112.7D108 E145 S146 H220 R221 H267D108-N143 PolarHBondContact OD1-N 2.72Å; D108-N143 PolarHBondContact OD1-OD1 2.92Å; D108-N143 PolarHBondContact OD2-OD1 3.3Å; N143-E145 PolarHBondContact O-N 2.65Å; N143-E145 VanDerWaalsContact O-N 3.16Å; N143-S146 PolarHBondContact O-N 2.84Å; N143-S146 PolarHBondContact O-OG 3.29Å; N143-H220 PolarHBondContact OD1-NE2 3.05Å; N143-R221 VanDerWaalsContact CB-NH2 3.26Å; N143-H267 PolarHBondContact OD1-CE1 3.18Å; N143-H267 PolarHBondContact OD1-ND1 3.22Å
144H95.8Very high95Very high30 Ų3027.5 Ų27.514%0.13914%0.138CC..G310 helixtrans-69-10.6175.3-80-84.3000113.5D108 Y111 D112D108-H144 HydrophobicContact CB-CB 4.45Å; D108-H144 VanDerWaalsContact CG-CD2 3.43Å; D108-H144 WeakPolarHBondContact OD1-CB 3.41Å; D108-H144 IonicContact OD1-CD2 2.62Å; D108-H144 PolarHBondContact OD1-CD2 3.35Å; D108-H144 IonicContact OD1-CG 3.31Å; D108-H144 PolarHBondContact OD1-N 3.18Å; D108-H144 IonicContact OD2-CD2 2.97Å; D108-H144 PolarHBondContact OD2-CD2 2.85Å; D108-H144 VanDerWaalsContact OD2-CD2 3.31Å; Y111-H144 AromaticContact CD1-CD2 3.68Å; Y111-H144 AromaticContact CD1-CE1 3.72Å; Y111-H144 AromaticContact CD1-NE2 3.48Å; Y111-H144 WeakPolarHBondContact CD1-NE2 3.37Å; Y111-H144 AromaticContact CE1-CD2 3.99Å; Y111-H144 AromaticContact CE1-NE2 3.9Å; D112-H144 IonicContact OD1-CE1 3.36Å; D112-H144 IonicContact OD1-CG 3.91Å; D112-H144 IonicContact OD1-ND1 3.06Å; D112-H144 PolarHBondContact OD1-ND1 2.84Å; D112-H144 IonicContact OD2-CE1 2.74Å; D112-H144 PolarHBondContact OD2-CE1 3.08Å; D112-H144 IonicContact OD2-ND1 2.65Å; D112-H144 PolarHBondContact OD2-ND1 3.31Å
145E96.4Very high94.9Very high3 Ų325.9 Ų25.91%0.01413%0.133CC..G310 helixtrans-90-19.1171.4-78.170.5-117.800113.1D108 I109 L113 A141 G142 N143 F150 I153D108-E145 PolarHBondContact N-OE2 3.24Å; I109-E145 WeakPolarHBondContact CA-OE1 3.39Å; I109-E145 VanDerWaalsContact CB-OE1 3.32Å; I109-E145 WeakPolarHBondContact CB-OE1 3.47Å; I109-E145 PolarHBondContact N-OE1 3.01Å; I109-E145 PolarHBondContact N-OE2 3.34Å; L113-E145 HydrophobicContact CD1-CG 4.47Å; A141-E145 HydrophobicContact CB-CB 3.82Å; A141-E145 HydrophobicContact CB-CG 4.43Å; G142-E145 PolarHBondContact N-OE2 2.97Å; G142-E145 PolarHBondContact O-N 3.41Å; N143-E145 PolarHBondContact O-N 2.65Å; N143-E145 VanDerWaalsContact O-N 3.16Å; E145-F150 HydrophobicContact CB-CD1 4.21Å; E145-F150 WeakPolarHBondContact O-CA 3.36Å; E145-F150 PolarHBondContact O-N 3.03Å; E145-I153 HydrophobicContact CB-CG2 4.17Å; E145-I153 HydrophobicContact CG-CB 4.04Å; E145-I153 HydrophobicContact CG-CD1 4.19Å; E145-I153 HydrophobicContact CG-CG2 4.2Å
146S93.5Very high94.8Very high8 Ų826.9 Ų26.96%0.05614%0.135CC..G310 helixtrans-79.2-29.8-172.6720000113.5N143 S148 H149 E190N143-S146 PolarHBondContact O-N 2.84Å; N143-S146 PolarHBondContact O-OG 3.29Å; S146-S148 PolarHBondContact O-N 3.45Å; S146-H149 WeakPolarHBondContact O-CA 3.26Å; S146-H149 PolarHBondContact O-N 3.4Å; S146-E190 WeakPolarHBondContact CB-OE1 3.43Å; S146-E190 PolarHBondContact OG-OE1 3.48Å
147D85.1Confident94.8Very high107 Ų10725 Ų2557%0.57212%0.122SC*.G310 helixtrans-56.6-23.2-178.6-76.1-18.7000114.1H114H114-D147 VanDerWaalsContact CE1-CB 3.46Å; H114-D147 WeakPolarHBondContact CE1-CB 3.49Å
148S85Confident94.7Very high1 Ų127.4 Ų27.41%0.00714%0.139CC..G310 helixtrans-102.823.6174.2680000114.2Q23 S146 F150 N151Q23-S148 VanDerWaalsContact CD-O 3.32Å; Q23-S148 PolarHBondContact NE2-O 3.1Å; Q23-S148 PolarHBondContact OE1-O 3.41Å; Q23-S148 VanDerWaalsContact OE1-O 3.12Å; S146-S148 PolarHBondContact O-N 3.45Å; S148-F150 PolarHBondContact O-N 3.45Å; S148-N151 WeakPolarHBondContact O-CB 3.11Å; S148-N151 PolarHBondContact O-N 3.2Å
149H90.9Very high94.6Very high147 Ų14726.8 Ų26.868%0.68114%0.136SC*.THydrogen-bonded Turntrans49.839.4-167.9-57.7-60.8000112.3S146 N151S146-H149 WeakPolarHBondContact O-CA 3.26Å; S146-H149 PolarHBondContact O-N 3.4Å; H149-N151 PolarHBondContact O-N 3.21Å
150F95.1Very high94.5Very high14 Ų1428.7 Ų28.76%0.06115%0.149CC..THydrogen-bonded Turntrans59.314-176.1-47.8-75.5000115A141 E145 S148 Q152 I153 I154 L169 E186 Y187A141-F150 HydrophobicContact CB-CD1 3.67Å; A141-F150 HydrophobicContact CB-CE1 3.72Å; E145-F150 HydrophobicContact CB-CD1 4.21Å; E145-F150 WeakPolarHBondContact O-CA 3.36Å; E145-F150 PolarHBondContact O-N 3.03Å; S148-F150 PolarHBondContact O-N 3.45Å; F150-Q152 VanDerWaalsContact C-N 3.31Å; F150-Q152 PolarHBondContact O-N 3.01Å; F150-I153 HydrophobicContact CB-CG2 3.77Å; F150-I153 HydrophobicContact CD1-CG2 4.43Å; F150-I153 WeakPolarHBondContact O-CG2 3.21Å; F150-I153 PolarHBondContact O-N 2.91Å; F150-I154 HydrophobicContact CB-CD1 3.9Å; F150-I154 HydrophobicContact CB-CG1 4.24Å; F150-I154 WeakPolarHBondContact O-CB 3.48Å; F150-I154 WeakPolarHBondContact O-CD1 3.45Å; F150-I154 WeakPolarHBondContact O-CG1 3.44Å; F150-I154 PolarHBondContact O-N 2.9Å; F150-L169 HydrophobicContact CB-CD1 3.96Å; F150-L169 HydrophobicContact CB-CD2 3.88Å; F150-L169 HydrophobicContact CD1-CD1 4.33Å; F150-L169 HydrophobicContact CD1-CD2 3.91Å; F150-L169 HydrophobicContact CD2-CD1 3.8Å; F150-L169 HydrophobicContact CE2-CD1 4.41Å; F150-L169 HydrophobicContact CG-CD1 3.76Å; F150-L169 HydrophobicContact CG-CD2 3.94Å; F150-E186 HydrophobicContact CE1-CB 4.24Å; F150-E186 HydrophobicContact CE1-CG 4.41Å; F150-E186 HydrophobicContact CZ-CB 3.95Å; F150-Y187 HydrophobicContact CE2-CE1 4.47Å
151N94.2Very high94.3Very high31 Ų3135.2 Ų35.217%0.16618%0.177CC..Hα-helixtrans-58.7-43.5-172.6-178.5-92.5000112W20 S148 H149 N155W20-N151 VanDerWaalsContact CE3-OD1 3.24Å; W20-N151 WeakPolarHBondContact CZ3-OD1 3.47Å; S148-N151 WeakPolarHBondContact O-CB 3.11Å; S148-N151 PolarHBondContact O-N 3.2Å; H149-N151 PolarHBondContact O-N 3.21Å; N151-N155 PolarHBondContact ND2-ND2 2.83Å; N151-N155 VanDerWaalsContact O-CB 3.32Å; N151-N155 WeakPolarHBondContact O-CB 3.15Å; N151-N155 PolarHBondContact O-N 2.69Å; N151-N155 PolarHBondContact O-ND2 3.16Å
152Q94.8Very high94.2Very high2 Ų238.2 Ų38.21%0.00919%0.193CC..Hα-helixtrans-64.7-48.1-179.1-63.5-69.9-10.700111.9D22 L113 H114 F150 N155 R156D22-Q152 PolarHBondContact OD2-NE2 3.16Å; L113-Q152 HydrophobicContact CB-CB 3.5Å; L113-Q152 HydrophobicContact CB-CG 3.73Å; L113-Q152 HydrophobicContact CD1-CB 3.86Å; L113-Q152 HydrophobicContact CG-CB 4.35Å; H114-Q152 HydrophobicContact CB-CG 3.76Å; F150-Q152 VanDerWaalsContact C-N 3.31Å; F150-Q152 PolarHBondContact O-N 3.01Å; Q152-N155 PolarHBondContact O-N 3.35Å; Q152-R156 VanDerWaalsContact O-CB 3.24Å; Q152-R156 WeakPolarHBondContact O-CB 3.3Å; Q152-R156 VanDerWaalsContact O-CG 3.27Å; Q152-R156 WeakPolarHBondContact O-CG 3.21Å; Q152-R156 PolarHBondContact O-N 2.9Å
153I95.6Very high93.9Very high0 Ų039.1 Ų39.10%020%0.202CC..Hα-helixtrans-67.2-40.3-178.7-173.4171.2000112I109 V139 F140 A141 E145 F150 N155 F157 N168 L169I109-I153 HydrophobicContact CD1-CD1 4.12Å; V139-I153 HydrophobicContact CG2-CD1 4.05Å; V139-I153 HydrophobicContact CG2-CG1 4.2Å; F140-I153 VanDerWaalsContact C-CD1 3.4Å; A141-I153 HydrophobicContact CB-CD1 4.14Å; E145-I153 HydrophobicContact CB-CG2 4.17Å; E145-I153 HydrophobicContact CG-CB 4.04Å; E145-I153 HydrophobicContact CG-CD1 4.19Å; E145-I153 HydrophobicContact CG-CG2 4.2Å; F150-I153 HydrophobicContact CB-CG2 3.77Å; F150-I153 HydrophobicContact CD1-CG2 4.43Å; F150-I153 WeakPolarHBondContact O-CG2 3.21Å; F150-I153 PolarHBondContact O-N 2.91Å; I153-N155 VanDerWaalsContact C-N 3.3Å; I153-N155 PolarHBondContact O-N 3.41Å; I153-F157 HydrophobicContact CB-CD2 4.41Å; I153-F157 HydrophobicContact CG1-CD2 3.92Å; I153-F157 PolarHBondContact O-N 2.99Å; I153-N168 PolarHBondContact O-ND2 2.95Å; I153-L169 HydrophobicContact CG2-CD2 3.78Å
154I95.7Very high93.9Very high48 Ų4841.6 Ų41.625%0.24622%0.218CC..Hα-helixtrans-58.3-45.2174.8-69.7167.8000110.2R34 F150 N167 N168R34-I154 PolarHBondContact NH2-O 3.1Å; R34-I154 VanDerWaalsContact NH2-O 3.07Å; F150-I154 HydrophobicContact CB-CD1 3.9Å; F150-I154 HydrophobicContact CB-CG1 4.24Å; F150-I154 WeakPolarHBondContact O-CB 3.48Å; F150-I154 WeakPolarHBondContact O-CD1 3.45Å; F150-I154 WeakPolarHBondContact O-CG1 3.44Å; F150-I154 PolarHBondContact O-N 2.9Å; I154-N167 HydrophobicContact CD1-CB 4.11Å; I154-N167 HydrophobicContact CG1-CB 3.98Å; I154-N167 VanDerWaalsContact CG1-O 3.26Å; I154-N167 WeakPolarHBondContact CG1-O 3.39Å; I154-N168 PolarHBondContact O-ND2 3.11Å
155N95.6Very high93.7Very high20 Ų2043 Ų4311%0.10722%0.222CC..Hα-helixtrans-89.5-26.6-170.4-72.8-66.8000114.4W20 T32 R34 N151 Q152 I153W20-N155 HydrophobicContact CB-CB 4.4Å; W20-N155 HydrophobicContact CD2-CB 3.47Å; W20-N155 VanDerWaalsContact CD2-CB 3.47Å; W20-N155 VanDerWaalsContact CE2-CB 3.49Å; W20-N155 HydrophobicContact CE3-CB 4.03Å; W20-N155 HydrophobicContact CG-CB 3.64Å; W20-N155 VanDerWaalsContact CG-CG 3.47Å; W20-N155 HydrophobicContact CZ2-CB 4.05Å; T32-N155 VanDerWaalsContact CB-O 3.26Å; T32-N155 WeakPolarHBondContact CB-O 3.41Å; T32-N155 WeakPolarHBondContact CG2-O 3.23Å; T32-N155 PolarHBondContact OG1-O 3.01Å; R34-N155 VanDerWaalsContact NH2-C 3.28Å; R34-N155 PolarHBondContact NH2-O 3.38Å; N151-N155 PolarHBondContact ND2-ND2 2.83Å; N151-N155 VanDerWaalsContact O-CB 3.32Å; N151-N155 WeakPolarHBondContact O-CB 3.15Å; N151-N155 PolarHBondContact O-N 2.69Å; N151-N155 PolarHBondContact O-ND2 3.16Å; Q152-N155 PolarHBondContact O-N 3.35Å; I153-N155 VanDerWaalsContact C-N 3.3Å; I153-N155 PolarHBondContact O-N 3.41Å
156R95.6Very high93.3Very high31 Ų3148 Ų4812%0.11725%0.25CC..Hα-helixtrans-88.2-34.4-178.7-67.7177.5177.1-77.8-2.8113.5W20 G118 D122 Q152W20-R156 HydrophobicContact CH2-CG 4.41Å; W20-R156 HydrophobicContact CZ2-CG 4.14Å; G118-R156 PolarHBondContact O-NH2 2.92Å; D122-R156 IonicContact OD1-CZ 3.69Å; D122-R156 VanDerWaalsContact OD1-CZ 3.23Å; D122-R156 IonicContact OD1-NH1 3.57Å; D122-R156 PolarHBondContact OD1-NH1 2.91Å; D122-R156 IonicContact OD1-NH2 2.95Å; D122-R156 PolarHBondContact OD1-NH2 3.03Å; D122-R156 IonicContact OD2-NH2 3.62Å; Q152-R156 VanDerWaalsContact O-CB 3.24Å; Q152-R156 WeakPolarHBondContact O-CB 3.3Å; Q152-R156 VanDerWaalsContact O-CG 3.27Å; Q152-R156 WeakPolarHBondContact O-CG 3.21Å; Q152-R156 PolarHBondContact O-N 2.9Å
157F96.8Very high93.1Very high10 Ų1048.9 Ų48.94%0.04425%0.254CS..  trans-104.8167.8-173-58.6-87.8000112.5R34 I109 L113 M125 Y137 V139 I153 M159 N168R34-F157 PolarHBondContact NH2-O 3.25Å; I109-F157 HydrophobicContact CD1-CE2 4.23Å; I109-F157 HydrophobicContact CD1-CZ 4.29Å; I109-F157 HydrophobicContact CG2-CZ 4.18Å; L113-F157 HydrophobicContact CD1-CE2 3.97Å; M125-F157 HydrophobicContact CE-CE1 4.01Å; M125-F157 HydrophobicContact CE-CZ 4.42Å; M125-F157 HydrophobicContact SD-CE1 3.73Å; M125-F157 HydrophobicContact SD-CE2 4.39Å; M125-F157 HydrophobicContact SD-CZ 3.57Å; M125-F157 VanDerWaalsContact SD-CZ 3.57Å; Y137-F157 HydrophobicContact CD1-CE1 4.21Å; Y137-F157 AromaticContact CE1-CE1 3.98Å; Y137-F157 HydrophobicContact CE1-CE1 3.98Å; V139-F157 HydrophobicContact CG1-CD1 4.06Å; V139-F157 HydrophobicContact CG1-CE1 4.06Å; V139-F157 HydrophobicContact CG2-CB 3.82Å; V139-F157 HydrophobicContact CG2-CD1 3.67Å; V139-F157 HydrophobicContact CG2-CD2 3.98Å; V139-F157 HydrophobicContact CG2-CE1 4.23Å; V139-F157 HydrophobicContact CG2-CE2 4.49Å; V139-F157 HydrophobicContact CG2-CG 3.54Å; I153-F157 HydrophobicContact CB-CD2 4.41Å; I153-F157 HydrophobicContact CG1-CD2 3.92Å; I153-F157 PolarHBondContact O-N 2.99Å; F157-M159 HydrophobicContact CB-CE 4.15Å; F157-N168 PolarHBondContact O-ND2 2.85Å
158T96.2Very high93.4Very high73 Ų7344.4 Ų44.445%0.44823%0.23SC..  trans-139.2113.3175.1-57.80000109.1R34R34-T158 WeakPolarHBondContact CD-OG1 3.43Å; R34-T158 PolarHBondContact NE-OG1 3.4Å
159M96.3Very high93.9Very high10 Ų1044.5 Ų44.55%0.04923%0.23CC..  trans-110.5170.6179-64.4-61.7122.200110.8Y137 M138 V139 F157 K161 N168 W171Y137-M159 WeakPolarHBondContact O-CE 3.18Å; M138-M159 HydrophobicContact CB-SD 4.32Å; M138-M159 HydrophobicContact CE-SD 3.85Å; M138-M159 HydrophobicContact SD-SD 4.42Å; V139-M159 HydrophobicContact CB-CE 4.41Å; V139-M159 HydrophobicContact CG2-CE 3.79Å; V139-M159 HydrophobicContact CG2-SD 4.47Å; V139-M159 PolarHBondContact N-SD 3.36Å; V139-M159 WeakPolarHBondContact O-CG 3.29Å; V139-M159 VanDerWaalsContact O-SD 3.34Å; F157-M159 HydrophobicContact CB-CE 4.15Å; M159-K161 PolarHBondContact O-N 2.97Å; M159-N168 HydrophobicContact CB-CB 3.95Å; M159-N168 HydrophobicContact CG-CB 3.74Å; M159-N168 PolarHBondContact N-OD1 2.83Å; M159-W171 VanDerWaalsContact CB-CD1 3.42Å; M159-W171 HydrophobicContact CB-CG 3.96Å; M159-W171 HydrophobicContact CG-CG 4.48Å; M159-W171 HydrophobicContact SD-CZ2 4.12Å
160P95.4Very high94.3Very high39 Ų3937.7 Ų37.725%0.25320%0.198SC..  trans-53.5128.7172.1-25.834.3000111.4M138 N162 W171 F173M138-P160 VanDerWaalsContact CE-CD 3.46Å; M138-P160 HydrophobicContact CE-CG 3.87Å; P160-N162 PolarHBondContact O-N 2.81Å; P160-N162 PolarHBondContact O-OD1 3.17Å; P160-W171 HydrophobicContact CB-CB 4.22Å; P160-W171 HydrophobicContact CG-CB 4.43Å; P160-F173 HydrophobicContact CG-CB 4.15Å; P160-F173 HydrophobicContact CG-CD1 4.37Å
161K91.9Very high94.4Very high138 Ų13837 Ų3760%0.620%0.196SC*.THydrogen-bonded Turntrans-85.150.3-178.9-61.3-174.2171.5-128.70111.3M159 D166M159-K161 PolarHBondContact O-N 2.97Å; K161-D166 VanDerWaalsContact CD-OD1 3.29Å; K161-D166 WeakPolarHBondContact CD-OD1 3.49Å; K161-D166 WeakPolarHBondContact CE-OD1 3.35Å; K161-D166 WeakPolarHBondContact CG-OD1 3.41Å; K161-D166 IonicContact NZ-OD1 3.79Å; K161-D166 PolarHBondContact NZ-OD1 2.82Å; K161-D166 IonicContact NZ-OD2 2.74Å; K161-D166 PolarHBondContact NZ-OD2 2.91Å
162N94.6Very high94.6Very high63 Ų6335.7 Ų35.734%0.33719%0.189SC..THydrogen-bonded Turntrans-115.9-3-177.768.6-15.8000114.1P160 W171 S172 W202P160-N162 PolarHBondContact O-N 2.81Å; P160-N162 PolarHBondContact O-OD1 3.17Å; N162-W171 WeakPolarHBondContact OD1-CA 3.44Å; N162-S172 PolarHBondContact ND2-N 2.84Å; N162-S172 PolarHBondContact ND2-O 2.75Å; N162-S172 PolarHBondContact ND2-OG 3.27Å; N162-S172 PolarHBondContact OD1-N 3.05Å; N162-S172 VanDerWaalsContact OD1-N 3.14Å; N162-S172 PolarHBondContact OD1-O 2.75Å; N162-W202 PolarHBondContact O-NE1 3.37Å
163G91.4Very high94.7Very high18 Ų1837 Ų3719%0.18619%0.194CC..SBendtrans-67.5177.9164.400000112.7Y165G163-Y165 VanDerWaalsContact C-N 3.3Å
164V95Very high94.7Very high81 Ų8142.1 Ų42.149%0.49122%0.222SC..SBendtrans-73.1-29177.5-175.30000111.4F170 A198 W202V164-F170 HydrophobicContact CB-CE2 4.37Å; V164-F170 HydrophobicContact CB-CZ 3.83Å; V164-F170 HydrophobicContact CG2-CE2 4.1Å; V164-F170 HydrophobicContact CG2-CZ 3.92Å; V164-F170 VanDerWaalsContact N-CE2 3.31Å; V164-A198 HydrophobicContact CG1-CB 4.45Å; V164-A198 HydrophobicContact CG2-CB 4.36Å; V164-W202 HydrophobicContact CG2-CB 3.72Å; V164-W202 HydrophobicContact CG2-CG 4.23Å
165Y91.9Very high94.6Very high58 Ų5840.9 Ų40.923%0.22721%0.214CC..SBendtrans-113.2142.2-178.7-51.7-55.1000110.4G163 N167 F170 E195 A198G163-Y165 VanDerWaalsContact C-N 3.3Å; Y165-N167 VanDerWaalsContact CB-CG 3.48Å; Y165-N167 VanDerWaalsContact CB-ND2 3.3Å; Y165-N167 WeakPolarHBondContact CB-ND2 3.48Å; Y165-N167 PolarHBondContact O-N 2.82Å; Y165-F170 AromaticContact CD2-CE1 3.69Å; Y165-F170 HydrophobicContact CD2-CE1 3.69Å; Y165-F170 HydrophobicContact CD2-CZ 4.1Å; Y165-F170 HydrophobicContact CE2-CE1 4.16Å; Y165-F170 HydrophobicContact CE2-CZ 4.47Å; Y165-E195 HydrophobicContact CE2-CB 4.19Å; Y165-E195 HydrophobicContact CE2-CG 3.88Å; Y165-A198 HydrophobicContact CE2-CB 4.37Å
166D88.1Confident94.4Very high109 Ų10941.5 Ų41.558%0.58323%0.225SC*.SBendtrans-83.162.3174.6-170.120.7000110.4K161K161-D166 VanDerWaalsContact CD-OD1 3.29Å; K161-D166 WeakPolarHBondContact CD-OD1 3.49Å; K161-D166 WeakPolarHBondContact CE-OD1 3.35Å; K161-D166 WeakPolarHBondContact CG-OD1 3.41Å; K161-D166 IonicContact NZ-OD1 3.79Å; K161-D166 PolarHBondContact NZ-OD1 2.82Å; K161-D166 IonicContact NZ-OD2 2.74Å; K161-D166 PolarHBondContact NZ-OD2 2.91Å
167N89.9Confident94.3Very high27 Ų2742.7 Ų42.714%0.14423%0.234CC..SBendtrans-139.711.4-168.571.92.5000115.3I154 Y165 L169I154-N167 HydrophobicContact CD1-CB 4.11Å; I154-N167 HydrophobicContact CG1-CB 3.98Å; I154-N167 VanDerWaalsContact CG1-O 3.26Å; I154-N167 WeakPolarHBondContact CG1-O 3.39Å; Y165-N167 VanDerWaalsContact CB-CG 3.48Å; Y165-N167 VanDerWaalsContact CB-ND2 3.3Å; Y165-N167 WeakPolarHBondContact CB-ND2 3.48Å; Y165-N167 PolarHBondContact O-N 2.82Å; N167-L169 HydrophobicContact CB-CG 4.44Å; N167-L169 WeakPolarHBondContact O-CG 3.31Å; N167-L169 PolarHBondContact O-N 2.84Å; N167-L169 WeakPolarHBondContact OD1-CB 3Å; N167-L169 PolarHBondContact OD1-N 3.23Å
168N92.4Very high94.4Very high13 Ų1342.2 Ų42.27%0.0723%0.232CC..SBendtrans62.73.1179.6-49.3-44.1000116.7I153 I154 F157 M159I153-N168 PolarHBondContact O-ND2 2.95Å; I154-N168 PolarHBondContact O-ND2 3.11Å; F157-N168 PolarHBondContact O-ND2 2.85Å; M159-N168 HydrophobicContact CB-CB 3.95Å; M159-N168 HydrophobicContact CG-CB 3.74Å; M159-N168 PolarHBondContact N-OD1 2.83Å
169L95.6Very high94.5Very high3 Ų339.1 Ų39.12%0.01621%0.212CC..SBendtrans-82.9-23-168.8-63.8-177.5000114.4A141 F150 I153 N167 N184 Y187A141-L169 HydrophobicContact CB-CD2 3.94Å; F150-L169 HydrophobicContact CB-CD1 3.96Å; F150-L169 HydrophobicContact CB-CD2 3.88Å; F150-L169 HydrophobicContact CD1-CD1 4.33Å; F150-L169 HydrophobicContact CD1-CD2 3.91Å; F150-L169 HydrophobicContact CD2-CD1 3.8Å; F150-L169 HydrophobicContact CE2-CD1 4.41Å; F150-L169 HydrophobicContact CG-CD1 3.76Å; F150-L169 HydrophobicContact CG-CD2 3.94Å; I153-L169 HydrophobicContact CG2-CD2 3.78Å; N167-L169 HydrophobicContact CB-CG 4.44Å; N167-L169 WeakPolarHBondContact O-CG 3.31Å; N167-L169 PolarHBondContact O-N 2.84Å; N167-L169 WeakPolarHBondContact OD1-CB 3Å; N167-L169 PolarHBondContact OD1-N 3.23Å; L169-N184 WeakPolarHBondContact O-CB 3.33Å; L169-Y187 HydrophobicContact CD1-CE1 4.29Å; L169-Y187 VanDerWaalsContact CD1-OH 3.26Å; L169-Y187 WeakPolarHBondContact CD1-OH 3.48Å
170F97.4Very high94.6Very high3 Ų338.7 Ų38.71%0.01321%0.21CC..SBendtrans-153.3146.4167.861-86.9000109.6V164 Y165 G182 Y187 Q199 W202V164-F170 HydrophobicContact CB-CE2 4.37Å; V164-F170 HydrophobicContact CB-CZ 3.83Å; V164-F170 HydrophobicContact CG2-CE2 4.1Å; V164-F170 HydrophobicContact CG2-CZ 3.92Å; V164-F170 VanDerWaalsContact N-CE2 3.31Å; Y165-F170 AromaticContact CD2-CE1 3.69Å; Y165-F170 HydrophobicContact CD2-CE1 3.69Å; Y165-F170 HydrophobicContact CD2-CZ 4.1Å; Y165-F170 HydrophobicContact CE2-CE1 4.16Å; Y165-F170 HydrophobicContact CE2-CZ 4.47Å; F170-G182 WeakPolarHBondContact CA-O 3.12Å; F170-G182 VanDerWaalsContact CB-O 3.3Å; F170-G182 WeakPolarHBondContact CB-O 3.41Å; F170-Y187 AromaticContact CD1-CE2 3.86Å; F170-Y187 HydrophobicContact CD1-CE2 3.86Å; F170-Y187 AromaticContact CE1-CE2 3.91Å; F170-Y187 HydrophobicContact CE1-CE2 3.91Å; F170-Q199 HydrophobicContact CB-CG 4.46Å; F170-Q199 HydrophobicContact CD1-CG 4.38Å; F170-Q199 HydrophobicContact CD2-CG 4.28Å; F170-Q199 HydrophobicContact CE1-CB 4.38Å; F170-Q199 HydrophobicContact CG-CG 4.14Å; F170-Q199 HydrophobicContact CZ-CB 4.41Å; F170-W202 AromaticContact CD2-CD2 3.78Å; F170-W202 HydrophobicContact CD2-CD2 3.78Å; F170-W202 AromaticContact CD2-CE3 3.57Å; F170-W202 HydrophobicContact CD2-CE3 3.57Å; F170-W202 HydrophobicContact CD2-CG 4.37Å; F170-W202 HydrophobicContact CD2-CH2 4.32Å; F170-W202 HydrophobicContact CD2-CZ2 4.48Å; F170-W202 AromaticContact CD2-CZ3 3.88Å; F170-W202 HydrophobicContact CD2-CZ3 3.88Å; F170-W202 HydrophobicContact CE2-CB 4.18Å; F170-W202 AromaticContact CE2-CD2 3.74Å; F170-W202 HydrophobicContact CE2-CD2 3.74Å; F170-W202 AromaticContact CE2-CE3 3.9Å; F170-W202 HydrophobicContact CE2-CE3 3.9Å; F170-W202 AromaticContact CE2-CG 3.84Å; F170-W202 HydrophobicContact CE2-CG 3.84Å
171W98.2Very high94.8Very high0 Ų036.8 Ų36.80%020%0.198CC..EExtended strand (participates in β ladder)trans-165.4165.7-170.347.2-99.4000109.8I104 M138 V139 F140 M159 P160 N162 F173 G182 W202 M218I104-W171 HydrophobicContact CG2-CH2 4.48Å; M138-W171 HydrophobicContact CB-CH2 3.82Å; M138-W171 HydrophobicContact CB-CZ2 3.88Å; M138-W171 HydrophobicContact CE-CE3 4.38Å; M138-W171 HydrophobicContact CE-CH2 4.21Å; M138-W171 HydrophobicContact CE-CZ2 4.32Å; M138-W171 HydrophobicContact CE-CZ3 4.27Å; V139-W171 PolarHBondContact O-NE1 3.03Å; F140-W171 HydrophobicContact CD1-CZ2 4.05Å; M159-W171 VanDerWaalsContact CB-CD1 3.42Å; M159-W171 HydrophobicContact CB-CG 3.96Å; M159-W171 HydrophobicContact CG-CG 4.48Å; M159-W171 HydrophobicContact SD-CZ2 4.12Å; P160-W171 HydrophobicContact CB-CB 4.22Å; P160-W171 HydrophobicContact CG-CB 4.43Å; N162-W171 WeakPolarHBondContact OD1-CA 3.44Å; W171-F173 AromaticContact CE3-CD1 3.64Å; W171-F173 HydrophobicContact CE3-CD1 3.64Å; W171-F173 AromaticContact CE3-CE1 3.99Å; W171-F173 HydrophobicContact CE3-CE1 3.99Å; W171-F173 HydrophobicContact CH2-CD1 4.2Å; W171-F173 AromaticContact CH2-CE1 3.67Å; W171-F173 HydrophobicContact CH2-CE1 3.67Å; W171-F173 AromaticContact CZ3-CD1 3.31Å; W171-F173 HydrophobicContact CZ3-CD1 3.31Å; W171-F173 AromaticContact CZ3-CE1 3.18Å; W171-F173 HydrophobicContact CZ3-CE1 3.18Å; W171-F173 HydrophobicContact CZ3-CZ 4.46Å; W171-G182 PolarHBondContact N-O 3.06Å; W171-G182 PolarHBondContact O-N 3.28Å; W171-W202 VanDerWaalsContact C-CH2 3.48Å; W171-M218 HydrophobicContact CH2-CE 4.49Å
172S98.5Very high95.1Very high3 Ų330.2 Ų30.22%0.02117%0.169CC..EExtended strand (participates in β ladder)trans-134.7157.5167.166.50000110.6N162 F180 D206N162-S172 PolarHBondContact ND2-N 2.84Å; N162-S172 PolarHBondContact ND2-O 2.75Å; N162-S172 PolarHBondContact ND2-OG 3.27Å; N162-S172 PolarHBondContact OD1-N 3.05Å; N162-S172 VanDerWaalsContact OD1-N 3.14Å; N162-S172 PolarHBondContact OD1-O 2.75Å; S172-F180 CarbonylContact C-O 3.54Å; S172-F180 WeakPolarHBondContact CA-O 3.43Å; S172-F180 WeakPolarHBondContact CB-O 3.37Å; S172-D206 WeakPolarHBondContact CB-OD2 3.5Å; S172-D206 PolarHBondContact OG-OD1 3.03Å; S172-D206 PolarHBondContact OG-OD2 2.8Å
173F96.9Very high95.3Very high30 Ų3027.3 Ų27.313%0.13215%0.153CC..EExtended strand (participates in β ladder)trans-153.6153167.367.4-87.6000111.2V102 I104 M138 P160 W171 Y175 F180V102-F173 HydrophobicContact CG2-CZ 4.11Å; I104-F173 HydrophobicContact CD1-CZ 4.43Å; M138-F173 HydrophobicContact CB-CE1 4.4Å; M138-F173 HydrophobicContact CE-CD1 3.6Å; M138-F173 HydrophobicContact CE-CE1 3.51Å; M138-F173 HydrophobicContact CE-CG 4.48Å; M138-F173 HydrophobicContact CE-CZ 4.33Å; M138-F173 HydrophobicContact CG-CE1 3.82Å; M138-F173 HydrophobicContact CG-CZ 3.94Å; M138-F173 HydrophobicContact SD-CE1 4.28Å; P160-F173 HydrophobicContact CG-CB 4.15Å; P160-F173 HydrophobicContact CG-CD1 4.37Å; W171-F173 AromaticContact CE3-CD1 3.64Å; W171-F173 HydrophobicContact CE3-CD1 3.64Å; W171-F173 AromaticContact CE3-CE1 3.99Å; W171-F173 HydrophobicContact CE3-CE1 3.99Å; W171-F173 HydrophobicContact CH2-CD1 4.2Å; W171-F173 AromaticContact CH2-CE1 3.67Å; W171-F173 HydrophobicContact CH2-CE1 3.67Å; W171-F173 AromaticContact CZ3-CD1 3.31Å; W171-F173 HydrophobicContact CZ3-CD1 3.31Å; W171-F173 AromaticContact CZ3-CE1 3.18Å; W171-F173 HydrophobicContact CZ3-CE1 3.18Å; W171-F173 HydrophobicContact CZ3-CZ 4.46Å; F173-Y175 HydrophobicContact CD2-CD2 4.29Å; F173-Y175 AromaticContact CE2-CD2 3.79Å; F173-Y175 HydrophobicContact CE2-CD2 3.79Å; F173-Y175 HydrophobicContact CE2-CG 4.23Å; F173-F180 HydrophobicContact CD1-CB 4.16Å; F173-F180 HydrophobicContact CD2-CD2 4.32Å; F173-F180 HydrophobicContact CE1-CB 3.77Å; F173-F180 HydrophobicContact CE1-CG 4.37Å; F173-F180 HydrophobicContact CE2-CB 4.25Å; F173-F180 AromaticContact CE2-CD2 3.63Å; F173-F180 HydrophobicContact CE2-CD2 3.63Å; F173-F180 HydrophobicContact CE2-CE2 4.37Å; F173-F180 HydrophobicContact CE2-CG 4.24Å; F173-F180 HydrophobicContact CZ-CB 3.81Å; F173-F180 AromaticContact CZ-CD2 3.75Å; F173-F180 HydrophobicContact CZ-CD2 3.75Å; F173-F180 AromaticContact CZ-CG 3.92Å; F173-F180 HydrophobicContact CZ-CG 3.92Å; F173-F180 PolarHBondContact N-O 3.04Å; F173-F180 PolarHBondContact O-N 2.79Å
174D95.4Very high95.6Very high107 Ų10726.5 Ų26.557%0.57215%0.145SC*.EExtended strand (participates in β ladder)trans-93.3136.8170.3-66.5-17.2000109.8T178 H179D174-T178 WeakPolarHBondContact CA-O 2.98Å; D174-H179 IonicContact OD1-CE1 3.86Å; D174-H179 IonicContact OD1-CG 2.75Å; D174-H179 IonicContact OD1-ND1 3.56Å; D174-H179 PolarHBondContact OD1-ND1 2.6Å
175Y92.8Very high95.7Very high23 Ų2322.8 Ų22.89%0.0912%0.123CC..EExtended strand (participates in β ladder)trans-142112.1173.2-156.6-60.2000109P65 L71 D101 V102 F173 L177 T178P65-Y175 HydrophobicContact CB-CD1 4.07Å; P65-Y175 HydrophobicContact CB-CE1 3.11Å; P65-Y175 HydrophobicContact CB-CE2 4.42Å; P65-Y175 WeakPolarHBondContact CB-OH 3.46Å; P65-Y175 VanDerWaalsContact CD-OH 3.25Å; P65-Y175 WeakPolarHBondContact CD-OH 3.22Å; P65-Y175 HydrophobicContact CG-CD1 4.09Å; P65-Y175 HydrophobicContact CG-CD2 4.45Å; P65-Y175 HydrophobicContact CG-CE1 3.32Å; P65-Y175 HydrophobicContact CG-CE2 3.77Å; P65-Y175 WeakPolarHBondContact CG-OH 3.21Å; L71-Y175 HydrophobicContact CD1-CD1 3.33Å; L71-Y175 HydrophobicContact CD1-CE1 3.43Å; L71-Y175 VanDerWaalsContact CD1-CE1 3.43Å; L71-Y175 HydrophobicContact CD1-CG 4.08Å; L71-Y175 HydrophobicContact CD2-CD1 4.34Å; L71-Y175 HydrophobicContact CG-CD1 4.32Å; D101-Y175 VanDerWaalsContact C-OH 3.25Å; D101-Y175 HydrophobicContact CB-CE1 3.82Å; D101-Y175 WeakPolarHBondContact CB-OH 3.45Å; D101-Y175 PolarHBondContact O-OH 2.88Å; V102-Y175 HydrophobicContact CB-CD2 4.38Å; V102-Y175 HydrophobicContact CB-CE2 4.02Å; F173-Y175 HydrophobicContact CD2-CD2 4.29Å; F173-Y175 AromaticContact CE2-CD2 3.79Å; F173-Y175 HydrophobicContact CE2-CD2 3.79Å; F173-Y175 HydrophobicContact CE2-CG 4.23Å; Y175-L177 PolarHBondContact O-N 3.26Å; Y175-T178 PolarHBondContact N-O 2.94Å; Y175-T178 PolarHBondContact O-N 2.91Å; Y175-T178 VanDerWaalsContact O-N 3.08Å
176G90.9Very high95.9Very high33 Ų3320 Ų2034%0.3411%0.112SC..THydrogen-bonded Turntrans57.5-120.4-17200000111.5T178G176-T178 VanDerWaalsContact C-N 3.34Å
177L94.9Very high96.4Very high56 Ų5615.1 Ų15.129%0.2939%0.085SC..THydrogen-bonded Turntrans-90.85.1-179-62.6177.8000113.8Y175 Q213 W214 V335 T338Y175-L177 PolarHBondContact O-N 3.26Å; L177-Q213 HydrophobicContact CB-CB 4.25Å; L177-Q213 HydrophobicContact CB-CG 4.46Å; L177-Q213 HydrophobicContact CD2-CG 4.17Å; L177-Q213 PolarHBondContact O-N 2.86Å; L177-W214 PolarHBondContact O-N 2.87Å; L177-V335 HydrophobicContact CB-CG1 4.39Å; L177-T338 HydrophobicContact CD1-CG2 4.16Å
178T97.8Very high96.7Very high0 Ų013.9 Ų13.90%08%0.078CC..EExtended strand (participates in β ladder)trans-121.6133.4-168-53.30000111.9D174 Y175 G176 F180 W214 I216D174-T178 WeakPolarHBondContact CA-O 2.98Å; Y175-T178 PolarHBondContact N-O 2.94Å; Y175-T178 PolarHBondContact O-N 2.91Å; Y175-T178 VanDerWaalsContact O-N 3.08Å; G176-T178 VanDerWaalsContact C-N 3.34Å; T178-F180 HydrophobicContact CG2-CD1 4.34Å; T178-F180 HydrophobicContact CG2-CD2 3.93Å; T178-F180 HydrophobicContact CG2-CE1 3.95Å; T178-F180 HydrophobicContact CG2-CE2 3.48Å; T178-F180 VanDerWaalsContact CG2-CE2 3.48Å; T178-F180 HydrophobicContact CG2-CG 4.33Å; T178-F180 HydrophobicContact CG2-CZ 3.5Å; T178-W214 CarbonylContact C-O 3.53Å; T178-W214 WeakPolarHBondContact CA-O 3.44Å; T178-W214 HydrophobicContact CG2-CB 4Å; T178-I216 HydrophobicContact CG2-CB 4.43Å; T178-I216 HydrophobicContact CG2-CD1 3.84Å; T178-I216 HydrophobicContact CG2-CG1 3.9Å
179H98.7Very high96.9Very high8 Ų813.7 Ų13.74%0.0378%0.079CC..EExtended strand (participates in β ladder)trans-98.4115.4168.3-175.770.5000109.1D174 I181 D206 N210 A212 W214 I216D174-H179 IonicContact OD1-CE1 3.86Å; D174-H179 IonicContact OD1-CG 2.75Å; D174-H179 IonicContact OD1-ND1 3.56Å; D174-H179 PolarHBondContact OD1-ND1 2.6Å; H179-I181 VanDerWaalsContact CD2-CG1 3.5Å; H179-I181 WeakPolarHBondContact CD2-CG1 3.12Å; H179-I181 WeakPolarHBondContact NE2-CG1 3.23Å; H179-D206 IonicContact CE1-OD1 3.44Å; H179-D206 IonicContact CE1-OD2 2.9Å; H179-D206 IonicContact NE2-OD1 3.64Å; H179-D206 IonicContact NE2-OD2 3.92Å; H179-D206 PolarHBondContact NE2-OD2 3.04Å; H179-N210 WeakPolarHBondContact CB-OD1 3.38Å; H179-A212 HydrophobicContact CB-CB 3.51Å; H179-W214 PolarHBondContact N-O 3.14Å; H179-I216 PolarHBondContact O-N 3.23Å
180F98.8Very high96.9Very high0 Ų017.4 Ų17.40%010%0.096CC..EExtended strand (participates in β ladder)trans-99.3134.2177.3-71.1-80.4000110.1L71 I104 S172 F173 T178 I216 M218 L333L71-F180 HydrophobicContact CD2-CE2 3.55Å; L71-F180 HydrophobicContact CD2-CZ 3.7Å; I104-F180 HydrophobicContact CD1-CD1 3.6Å; I104-F180 HydrophobicContact CD1-CE1 3.79Å; I104-F180 HydrophobicContact CD1-CG 4.14Å; I104-F180 HydrophobicContact CD1-CZ 4.47Å; S172-F180 CarbonylContact C-O 3.54Å; S172-F180 WeakPolarHBondContact CA-O 3.43Å; S172-F180 WeakPolarHBondContact CB-O 3.37Å; F173-F180 HydrophobicContact CD1-CB 4.16Å; F173-F180 HydrophobicContact CD2-CD2 4.32Å; F173-F180 HydrophobicContact CE1-CB 3.77Å; F173-F180 HydrophobicContact CE1-CG 4.37Å; F173-F180 HydrophobicContact CE2-CB 4.25Å; F173-F180 AromaticContact CE2-CD2 3.63Å; F173-F180 HydrophobicContact CE2-CD2 3.63Å; F173-F180 HydrophobicContact CE2-CE2 4.37Å; F173-F180 HydrophobicContact CE2-CG 4.24Å; F173-F180 HydrophobicContact CZ-CB 3.81Å; F173-F180 AromaticContact CZ-CD2 3.75Å; F173-F180 HydrophobicContact CZ-CD2 3.75Å; F173-F180 AromaticContact CZ-CG 3.92Å; F173-F180 HydrophobicContact CZ-CG 3.92Å; F173-F180 PolarHBondContact N-O 3.04Å; F173-F180 PolarHBondContact O-N 2.79Å; T178-F180 HydrophobicContact CG2-CD1 4.34Å; T178-F180 HydrophobicContact CG2-CD2 3.93Å; T178-F180 HydrophobicContact CG2-CE1 3.95Å; T178-F180 HydrophobicContact CG2-CE2 3.48Å; T178-F180 VanDerWaalsContact CG2-CE2 3.48Å; T178-F180 HydrophobicContact CG2-CG 4.33Å; T178-F180 HydrophobicContact CG2-CZ 3.5Å; F180-I216 WeakPolarHBondContact CA-O 3.42Å; F180-I216 HydrophobicContact CD1-CB 3.98Å; F180-I216 HydrophobicContact CD1-CG2 4.22Å; F180-I216 HydrophobicContact CE1-CB 4.09Å; F180-I216 HydrophobicContact CE1-CD1 3.89Å; F180-I216 HydrophobicContact CE1-CG1 4.46Å; F180-I216 HydrophobicContact CE1-CG2 4.26Å; F180-I216 HydrophobicContact CZ-CD1 4.38Å; F180-M218 HydrophobicContact CB-CE 3.92Å; F180-M218 HydrophobicContact CD1-CE 3.84Å; F180-M218 HydrophobicContact CD1-SD 4.21Å; F180-M218 HydrophobicContact CG-CE 4.36Å; F180-L333 HydrophobicContact CE1-CD2 4.06Å; F180-L333 HydrophobicContact CZ-CD2 4.04Å
181I98.9Very high96.8Very high0 Ų020.9 Ų20.90%011%0.114CC..EExtended strand (participates in β ladder)trans-127120.6178.4-59.5166.5000108.5H179 L183 W202 L203 L207 T215 I216 V217 M218H179-I181 VanDerWaalsContact CD2-CG1 3.5Å; H179-I181 WeakPolarHBondContact CD2-CG1 3.12Å; H179-I181 WeakPolarHBondContact NE2-CG1 3.23Å; I181-L183 HydrophobicContact CG2-CD2 3.69Å; I181-L183 HydrophobicContact CG2-CG 3.93Å; I181-W202 HydrophobicContact CG2-CH2 4.11Å; I181-W202 HydrophobicContact CG2-CZ3 4.12Å; I181-L203 HydrophobicContact CD1-CD1 4.02Å; I181-L203 HydrophobicContact CG2-CD1 3.91Å; I181-L207 HydrophobicContact CD1-CD2 3.62Å; I181-L207 HydrophobicContact CD1-CG 4.28Å; I181-T215 HydrophobicContact CD1-CG2 4.16Å; I181-I216 PolarHBondContact N-O 2.8Å; I181-V217 HydrophobicContact CB-CG2 4.18Å; I181-V217 HydrophobicContact CD1-CG2 3.92Å; I181-V217 CarbonylContact O-C 3.42Å; I181-M218 VanDerWaalsContact O-CE 3.26Å; I181-M218 WeakPolarHBondContact O-CE 3.3Å; I181-M218 PolarHBondContact O-N 3.18Å
182G98.6Very high96.7Very high0 Ų023.7 Ų23.70%013%0.127CC..EExtended strand (participates in β ladder)trans-101.7125169.100000110.4F170 W171 M218F170-G182 WeakPolarHBondContact CA-O 3.12Å; F170-G182 VanDerWaalsContact CB-O 3.3Å; F170-G182 WeakPolarHBondContact CB-O 3.41Å; W171-G182 PolarHBondContact N-O 3.06Å; W171-G182 PolarHBondContact O-N 3.28Å; G182-M218 WeakPolarHBondContact CA-O 3.25Å
183L98.6Very high96.7Very high1 Ų125.2 Ų25.21%0.00514%0.136CC..  trans-117.1147.9179.1-55.1174.6000110.8I181 Q199 W202 L203 V217 M218 F219 L251I181-L183 HydrophobicContact CG2-CD2 3.69Å; I181-L183 HydrophobicContact CG2-CG 3.93Å; L183-Q199 HydrophobicContact CD2-CG 4.04Å; L183-W202 HydrophobicContact CD2-CE3 4.45Å; L183-W202 HydrophobicContact CD2-CZ3 3.75Å; L183-L203 HydrophobicContact CD1-CD2 3.79Å; L183-L203 HydrophobicContact CD2-CD1 4.25Å; L183-L203 HydrophobicContact CD2-CD2 4.24Å; L183-V217 HydrophobicContact CD1-CG1 3.73Å; L183-V217 HydrophobicContact CG-CG1 4.29Å; L183-M218 PolarHBondContact N-O 2.73Å; L183-F219 HydrophobicContact CB-CB 4.15Å; L183-F219 HydrophobicContact CD1-CD1 4.44Å; L183-F219 WeakPolarHBondContact O-CB 3.22Å; L183-L251 HydrophobicContact CD1-CD1 4.2Å
184N97.9Very high96.7Very high1 Ų130.7 Ų30.71%0.00516%0.16CC..  trans-86.7111.8172-168.1-9.5000110.2L169 E186 Y187 Q199L169-N184 WeakPolarHBondContact O-CB 3.33Å; N184-E186 VanDerWaalsContact C-N 3.34Å; N184-E186 VanDerWaalsContact OD1-CB 3.29Å; N184-E186 WeakPolarHBondContact OD1-CB 3.43Å; N184-E186 PolarHBondContact OD1-N 2.9Å; N184-Y187 HydrophobicContact CB-CD2 3.8Å; N184-Y187 HydrophobicContact CB-CE2 3.92Å; N184-Y187 HydrophobicContact CB-CG 4.18Å; N184-Y187 WeakPolarHBondContact ND2-CE1 3.42Å; N184-Q199 PolarHBondContact O-NE2 2.84Å
185S97.4Very high96.8Very high4 Ų427.9 Ų27.93%0.02814%0.144CC..SBendtrans-74.4-25173.349.30000112.9Y187 Y188 A189 H220 R221S185-Y187 PolarHBondContact O-N 3Å; S185-Y188 WeakPolarHBondContact O-CB 3.28Å; S185-Y188 PolarHBondContact O-N 3.48Å; S185-A189 PolarHBondContact O-N 3.26Å; S185-H220 WeakPolarHBondContact OG-CB 3.48Å; S185-H220 PolarHBondContact OG-N 2.82Å; S185-R221 PolarHBondContact OG-N 3.43Å; S185-R221 VanDerWaalsContact OG-N 3.12Å
186E96.9Very high97.1Very high0 Ų026.8 Ų26.80%014%0.139CC..Hα-helixtrans-69-23.6-176.1-54.4-42.3106.500112.1G142 F150 N184 Y188 A189 E190 R221G142-E186 WeakPolarHBondContact O-CG 3.36Å; F150-E186 HydrophobicContact CE1-CB 4.24Å; F150-E186 HydrophobicContact CE1-CG 4.41Å; F150-E186 HydrophobicContact CZ-CB 3.95Å; N184-E186 VanDerWaalsContact C-N 3.34Å; N184-E186 VanDerWaalsContact OD1-CB 3.29Å; N184-E186 WeakPolarHBondContact OD1-CB 3.43Å; N184-E186 PolarHBondContact OD1-N 2.9Å; E186-Y188 PolarHBondContact O-N 2.84Å; E186-Y188 VanDerWaalsContact O-N 3.15Å; E186-A189 PolarHBondContact O-N 2.98Å; E186-E190 WeakPolarHBondContact O-CB 3.21Å; E186-E190 PolarHBondContact O-N 3.22Å; E186-R221 VanDerWaalsContact CD-NE 3.27Å; E186-R221 WeakPolarHBondContact OE1-CD 3.39Å; E186-R221 WeakPolarHBondContact OE1-CG 3.2Å; E186-R221 IonicContact OE1-CZ 3.77Å; E186-R221 IonicContact OE1-NE 2.71Å; E186-R221 PolarHBondContact OE1-NE 2.85Å; E186-R221 IonicContact OE2-CZ 3.82Å; E186-R221 VanDerWaalsContact OE2-CZ 3.22Å; E186-R221 IonicContact OE2-NE 3.5Å; E186-R221 PolarHBondContact OE2-NE 2.83Å; E186-R221 IonicContact OE2-NH2 3.53Å; E186-R221 PolarHBondContact OE2-NH2 3.37Å
187Y97.3Very high97.4Very high6 Ų628.8 Ų28.82%0.02414%0.14CC..Hα-helixtrans-58.4-27.3169.8-68.8-22.6000113.5F150 L169 F170 N184 S185 H192 E195 Q199F150-Y187 HydrophobicContact CE2-CE1 4.47Å; L169-Y187 HydrophobicContact CD1-CE1 4.29Å; L169-Y187 VanDerWaalsContact CD1-OH 3.26Å; L169-Y187 WeakPolarHBondContact CD1-OH 3.48Å; F170-Y187 AromaticContact CD1-CE2 3.86Å; F170-Y187 HydrophobicContact CD1-CE2 3.86Å; F170-Y187 AromaticContact CE1-CE2 3.91Å; F170-Y187 HydrophobicContact CE1-CE2 3.91Å; N184-Y187 HydrophobicContact CB-CD2 3.8Å; N184-Y187 HydrophobicContact CB-CE2 3.92Å; N184-Y187 HydrophobicContact CB-CG 4.18Å; N184-Y187 WeakPolarHBondContact ND2-CE1 3.42Å; S185-Y187 PolarHBondContact O-N 3Å; Y187-H192 HydrophobicContact CD1-CB 3.89Å; Y187-H192 HydrophobicContact CG-CB 4.4Å; Y187-H192 PolarHBondContact O-N 2.84Å; Y187-E195 HydrophobicContact CD1-CB 3.69Å; Y187-E195 HydrophobicContact CD1-CG 4.31Å; Y187-E195 HydrophobicContact CD2-CB 3.76Å; Y187-E195 HydrophobicContact CE1-CB 3.7Å; Y187-E195 HydrophobicContact CE1-CG 3.93Å; Y187-E195 HydrophobicContact CE2-CB 3.78Å; Y187-E195 HydrophobicContact CG-CB 3.72Å; Y187-Q199 HydrophobicContact CD2-CB 4.45Å
188Y97.4Very high97.6Very high0 Ų027 Ų270%013%0.133CC..Hα-helixtrans-90-48.3175.1-65.5-95.2000111.3S185 E186 E190 I191 A196 S241 L248 P249 L251S185-Y188 WeakPolarHBondContact O-CB 3.28Å; S185-Y188 PolarHBondContact O-N 3.48Å; E186-Y188 PolarHBondContact O-N 2.84Å; E186-Y188 VanDerWaalsContact O-N 3.15Å; Y188-E190 VanDerWaalsContact C-N 3.29Å; Y188-E190 PolarHBondContact O-N 3.43Å; Y188-I191 WeakPolarHBondContact O-CD1 3.28Å; Y188-I191 PolarHBondContact O-N 3.49Å; Y188-I191 VanDerWaalsContact O-N 3.17Å; Y188-A196 HydrophobicContact CD1-CB 4.35Å; Y188-A196 HydrophobicContact CD2-CB 4.43Å; Y188-A196 HydrophobicContact CE1-CB 4.09Å; Y188-A196 HydrophobicContact CE2-CB 4.16Å; Y188-S241 VanDerWaalsContact CG-CB 3.43Å; Y188-L248 HydrophobicContact CD1-CB 4.31Å; Y188-L248 HydrophobicContact CD1-CD1 4.41Å; Y188-L248 HydrophobicContact CD1-CD2 4.48Å; Y188-L248 HydrophobicContact CE1-CB 4.39Å; Y188-P249 VanDerWaalsContact CE1-O 3.24Å; Y188-P249 WeakPolarHBondContact CE1-O 3.49Å; Y188-P249 PolarHBondContact OH-O 3.25Å; Y188-L251 HydrophobicContact CE2-CD1 3.9Å; Y188-L251 HydrophobicContact CE2-CG 4.42Å; Y188-L251 WeakPolarHBondContact OH-CD2 3.44Å
189A95.8Very high97.6Very high10 Ų1027 Ų278%0.08313%0.133CC..Hα-helixtrans-63.6-33.4-175.800000113.1S185 E186 R221S185-A189 PolarHBondContact O-N 3.26Å; E186-A189 PolarHBondContact O-N 2.98Å; A189-R221 VanDerWaalsContact CB-NE 3.27Å
190E95.4Very high97.6Very high81 Ų8129.2 Ų29.238%0.37914%0.142SC..THydrogen-bonded Turntrans-99.67177.6-62-176-174.800113.8S146 E186 Y188 H192S146-E190 WeakPolarHBondContact CB-OE1 3.43Å; S146-E190 PolarHBondContact OG-OE1 3.48Å; E186-E190 WeakPolarHBondContact O-CB 3.21Å; E186-E190 PolarHBondContact O-N 3.22Å; Y188-E190 VanDerWaalsContact C-N 3.29Å; Y188-E190 PolarHBondContact O-N 3.43Å; E190-H192 WeakPolarHBondContact CB-NE2 3.36Å; E190-H192 PolarHBondContact O-N 2.92Å; E190-H192 IonicContact OE2-CD2 3.76Å; E190-H192 IonicContact OE2-CE1 3.6Å; E190-H192 IonicContact OE2-NE2 3.25Å; E190-H192 PolarHBondContact OE2-NE2 3.48Å
191I96.1Very high97.6Very high75 Ų7535.8 Ų35.839%0.38517%0.17SC..THydrogen-bonded Turntrans60.543.6176.2-41.4-59.9000112.7Y188 T193 L237 L240 L248Y188-I191 WeakPolarHBondContact O-CD1 3.28Å; Y188-I191 PolarHBondContact O-N 3.49Å; Y188-I191 VanDerWaalsContact O-N 3.17Å; I191-T193 PolarHBondContact O-N 2.88Å; I191-L237 HydrophobicContact CD1-CD2 3.76Å; I191-L237 HydrophobicContact CG1-CD2 4.46Å; I191-L240 HydrophobicContact CD1-CD2 3.49Å; I191-L240 VanDerWaalsContact CD1-CD2 3.49Å; I191-L248 HydrophobicContact CD1-CD1 4.29Å
192H96.2Very high97.6Very high59 Ų5937.1 Ų37.127%0.27318%0.175SC..  trans-79.370.6168.8-61.3-77000110.1Y187 E190 K194 E195 A196Y187-H192 HydrophobicContact CD1-CB 3.89Å; Y187-H192 HydrophobicContact CG-CB 4.4Å; Y187-H192 PolarHBondContact O-N 2.84Å; E190-H192 WeakPolarHBondContact CB-NE2 3.36Å; E190-H192 PolarHBondContact O-N 2.92Å; E190-H192 IonicContact OE2-CD2 3.76Å; E190-H192 IonicContact OE2-CE1 3.6Å; E190-H192 IonicContact OE2-NE2 3.25Å; E190-H192 PolarHBondContact OE2-NE2 3.48Å; H192-K194 VanDerWaalsContact C-N 3.32Å; H192-K194 PolarHBondContact O-N 3.03Å; H192-E195 HydrophobicContact CB-CB 4.01Å; H192-E195 HydrophobicContact CB-CG 4.35Å; H192-E195 PolarHBondContact O-N 2.98Å; H192-E195 VanDerWaalsContact O-N 3.11Å; H192-A196 WeakPolarHBondContact O-CB 3.46Å; H192-A196 PolarHBondContact O-N 3.28Å
193T97.4Very high97.6Very high36 Ų3637.1 Ų37.122%0.22118%0.175CC..Hα-helixtrans-55.2-41.4-167.7-590000114.1I191 Q197 E247 L248I191-T193 PolarHBondContact O-N 2.88Å; T193-Q197 WeakPolarHBondContact O-CB 3.31Å; T193-Q197 VanDerWaalsContact O-CG 3.29Å; T193-Q197 WeakPolarHBondContact O-CG 3.33Å; T193-Q197 PolarHBondContact O-N 2.86Å; T193-E247 HydrophobicContact CG2-CB 4.3Å; T193-L248 HydrophobicContact CG2-CD2 4.18Å
194K97.8Very high97.6Very high145 Ų14541.6 Ų41.663%0.6320%0.196SC*.Hα-helixtrans-65.8-45179.8174.9-169170.9-1660110.9H192 Q197 A198H192-K194 VanDerWaalsContact C-N 3.32Å; H192-K194 PolarHBondContact O-N 3.03Å; K194-Q197 PolarHBondContact O-N 3.06Å; K194-A198 WeakPolarHBondContact O-CB 3.4Å; K194-A198 PolarHBondContact O-N 3.32Å
195E97.7Very high97.7Very high48 Ų4843.6 Ų43.622%0.22421%0.213CC..Hα-helixtrans-67.8-44.1-178.8-68.363.6-14600110.9Y165 Y187 H192 Q197 A198 Q199Y165-E195 HydrophobicContact CE2-CB 4.19Å; Y165-E195 HydrophobicContact CE2-CG 3.88Å; Y187-E195 HydrophobicContact CD1-CB 3.69Å; Y187-E195 HydrophobicContact CD1-CG 4.31Å; Y187-E195 HydrophobicContact CD2-CB 3.76Å; Y187-E195 HydrophobicContact CE1-CB 3.7Å; Y187-E195 HydrophobicContact CE1-CG 3.93Å; Y187-E195 HydrophobicContact CE2-CB 3.78Å; Y187-E195 HydrophobicContact CG-CB 3.72Å; H192-E195 HydrophobicContact CB-CB 4.01Å; H192-E195 HydrophobicContact CB-CG 4.35Å; H192-E195 PolarHBondContact O-N 2.98Å; H192-E195 VanDerWaalsContact O-N 3.11Å; E195-Q197 PolarHBondContact O-N 2.86Å; E195-A198 PolarHBondContact O-N 3.44Å; E195-Q199 WeakPolarHBondContact O-CB 3.35Å; E195-Q199 PolarHBondContact O-N 3.21Å
196A98.1Very high97.8Very high0 Ų044.6 Ų44.60%022%0.218CC..Hα-helixtrans-60.7-43.8174.500000112.2Y188 H192 Q199 Y200 L248Y188-A196 HydrophobicContact CD1-CB 4.35Å; Y188-A196 HydrophobicContact CD2-CB 4.43Å; Y188-A196 HydrophobicContact CE1-CB 4.09Å; Y188-A196 HydrophobicContact CE2-CB 4.16Å; H192-A196 WeakPolarHBondContact O-CB 3.46Å; H192-A196 PolarHBondContact O-N 3.28Å; A196-Q199 PolarHBondContact O-N 2.94Å; A196-Y200 WeakPolarHBondContact O-CB 3.42Å; A196-Y200 PolarHBondContact O-N 2.84Å; A196-L248 HydrophobicContact CB-CD2 3.46Å; A196-L248 VanDerWaalsContact CB-CD2 3.46Å
197Q98.4Very high97.8Very high75 Ų7545.1 Ų45.135%0.3522%0.22SC..Hα-helixtrans-65.3-38.6175.6-74.8-176.713.900112.6T193 K194 E195 K201 E247T193-Q197 WeakPolarHBondContact O-CB 3.31Å; T193-Q197 VanDerWaalsContact O-CG 3.29Å; T193-Q197 WeakPolarHBondContact O-CG 3.33Å; T193-Q197 PolarHBondContact O-N 2.86Å; K194-Q197 PolarHBondContact O-N 3.06Å; E195-Q197 PolarHBondContact O-N 2.86Å; Q197-K201 WeakPolarHBondContact O-CG 3.46Å; Q197-K201 PolarHBondContact O-N 3.25Å; Q197-K201 VanDerWaalsContact O-N 3.1Å; Q197-E247 PolarHBondContact NE2-O 2.62Å
198A98.5Very high97.9Very high19 Ų1948.4 Ų48.416%0.15725%0.249CC..Hα-helixtrans-65.1-46175.600000111.4V164 Y165 K194 E195 Y200 K201 W202V164-A198 HydrophobicContact CG1-CB 4.45Å; V164-A198 HydrophobicContact CG2-CB 4.36Å; Y165-A198 HydrophobicContact CE2-CB 4.37Å; K194-A198 WeakPolarHBondContact O-CB 3.4Å; K194-A198 PolarHBondContact O-N 3.32Å; E195-A198 PolarHBondContact O-N 3.44Å; A198-Y200 PolarHBondContact O-N 2.73Å; A198-K201 PolarHBondContact O-N 2.98Å; A198-W202 WeakPolarHBondContact O-CB 3.07Å; A198-W202 PolarHBondContact O-N 3.41Å
199Q98.5Very high97.9Very high0 Ų056.1 Ų56.10%028%0.282CS..Hα-helixtrans-59.6-44.9175.4-177.8172.5-82.800111.4F170 L183 N184 Y187 E195 A196 W202 L203F170-Q199 HydrophobicContact CB-CG 4.46Å; F170-Q199 HydrophobicContact CD1-CG 4.38Å; F170-Q199 HydrophobicContact CD2-CG 4.28Å; F170-Q199 HydrophobicContact CE1-CB 4.38Å; F170-Q199 HydrophobicContact CG-CG 4.14Å; F170-Q199 HydrophobicContact CZ-CB 4.41Å; L183-Q199 HydrophobicContact CD2-CG 4.04Å; N184-Q199 PolarHBondContact O-NE2 2.84Å; Y187-Q199 HydrophobicContact CD2-CB 4.45Å; E195-Q199 WeakPolarHBondContact O-CB 3.35Å; E195-Q199 PolarHBondContact O-N 3.21Å; A196-Q199 PolarHBondContact O-N 2.94Å; Q199-W202 PolarHBondContact O-N 3.49Å; Q199-L203 VanDerWaalsContact O-CB 3.29Å; Q199-L203 WeakPolarHBondContact O-CB 3.33Å; Q199-L203 PolarHBondContact O-N 3.21Å
200Y98.8Very high98Very high54 Ų5457.3 Ų57.321%0.21229%0.287CS..Hα-helixtrans-61.5-47.3178.2-177.5-87.4000112.7A196 A198 W202 L203 Q204 P249 G250 L251 L254A196-Y200 WeakPolarHBondContact O-CB 3.42Å; A196-Y200 PolarHBondContact O-N 2.84Å; A198-Y200 PolarHBondContact O-N 2.73Å; Y200-W202 VanDerWaalsContact C-N 3.31Å; Y200-W202 PolarHBondContact O-N 3.37Å; Y200-L203 PolarHBondContact O-N 2.97Å; Y200-Q204 PolarHBondContact O-N 2.79Å; Y200-P249 VanDerWaalsContact CB-CG 3.41Å; Y200-P249 HydrophobicContact CD1-CB 3.97Å; Y200-P249 HydrophobicContact CD1-CG 3.94Å; Y200-P249 HydrophobicContact CD2-CB 3.5Å; Y200-P249 VanDerWaalsContact CD2-CB 3.5Å; Y200-P249 HydrophobicContact CD2-CG 3.51Å; Y200-P249 HydrophobicContact CE1-CB 4.17Å; Y200-P249 HydrophobicContact CE2-CB 3.72Å; Y200-P249 HydrophobicContact CE2-CG 4.26Å; Y200-P249 HydrophobicContact CG-CB 3.64Å; Y200-P249 HydrophobicContact CG-CG 3.32Å; Y200-G250 WeakPolarHBondContact CE2-O 3.34Å; Y200-L251 HydrophobicContact CD2-CD2 3.9Å; Y200-L254 HydrophobicContact CD2-CD2 4.17Å; Y200-L254 HydrophobicContact CE2-CB 4.15Å; Y200-L254 HydrophobicContact CE2-CD2 3.73Å; Y200-L254 HydrophobicContact CE2-CG 4.5Å
201K98.7Very high98Very high137 Ų13762.4 Ų62.460%0.59631%0.308SS*.Hα-helixtrans-63.3-40178.4-73.3174.3-177172.30111.7Q197 A198 A205Q197-K201 WeakPolarHBondContact O-CG 3.46Å; Q197-K201 PolarHBondContact O-N 3.25Å; Q197-K201 VanDerWaalsContact O-N 3.1Å; A198-K201 PolarHBondContact O-N 2.98Å; K201-A205 PolarHBondContact O-N 2.83Å
202W98.8Very high98.1Very high29 Ų2960 Ų6011%0.1130%0.3CS..Hα-helixtrans-61.7-50174.2168.985.7000111.3N162 V164 F170 W171 I181 L183 A198 Q199 Y200 Q204 A205 D206N162-W202 PolarHBondContact O-NE1 3.37Å; V164-W202 HydrophobicContact CG2-CB 3.72Å; V164-W202 HydrophobicContact CG2-CG 4.23Å; F170-W202 AromaticContact CD2-CD2 3.78Å; F170-W202 HydrophobicContact CD2-CD2 3.78Å; F170-W202 AromaticContact CD2-CE3 3.57Å; F170-W202 HydrophobicContact CD2-CE3 3.57Å; F170-W202 HydrophobicContact CD2-CG 4.37Å; F170-W202 HydrophobicContact CD2-CH2 4.32Å; F170-W202 HydrophobicContact CD2-CZ2 4.48Å; F170-W202 AromaticContact CD2-CZ3 3.88Å; F170-W202 HydrophobicContact CD2-CZ3 3.88Å; F170-W202 HydrophobicContact CE2-CB 4.18Å; F170-W202 AromaticContact CE2-CD2 3.74Å; F170-W202 HydrophobicContact CE2-CD2 3.74Å; F170-W202 AromaticContact CE2-CE3 3.9Å; F170-W202 HydrophobicContact CE2-CE3 3.9Å; F170-W202 AromaticContact CE2-CG 3.84Å; F170-W202 HydrophobicContact CE2-CG 3.84Å; W171-W202 VanDerWaalsContact C-CH2 3.48Å; I181-W202 HydrophobicContact CG2-CH2 4.11Å; I181-W202 HydrophobicContact CG2-CZ3 4.12Å; L183-W202 HydrophobicContact CD2-CE3 4.45Å; L183-W202 HydrophobicContact CD2-CZ3 3.75Å; A198-W202 WeakPolarHBondContact O-CB 3.07Å; A198-W202 PolarHBondContact O-N 3.41Å; Q199-W202 PolarHBondContact O-N 3.49Å; Y200-W202 VanDerWaalsContact C-N 3.31Å; Y200-W202 PolarHBondContact O-N 3.37Å; W202-Q204 VanDerWaalsContact C-N 3.3Å; W202-Q204 PolarHBondContact O-N 2.95Å; W202-A205 CarbonylContact O-C 3.45Å; W202-A205 WeakPolarHBondContact O-CA 3.11Å; W202-A205 WeakPolarHBondContact O-CB 2.93Å; W202-A205 PolarHBondContact O-N 2.77Å; W202-D206 HydrophobicContact CZ2-CB 4.33Å; W202-D206 WeakPolarHBondContact O-CB 2.87Å; W202-D206 PolarHBondContact O-N 3.45Å
203L98.9Very high98Very high0 Ų061.5 Ų61.50%031%0.307CS..Hα-helixtrans-59.4-41.2179.9176.161.7000111.7I181 L183 Q199 Y200 A205 D206 L207 L251 L254 L255I181-L203 HydrophobicContact CD1-CD1 4.02Å; I181-L203 HydrophobicContact CG2-CD1 3.91Å; L183-L203 HydrophobicContact CD1-CD2 3.79Å; L183-L203 HydrophobicContact CD2-CD1 4.25Å; L183-L203 HydrophobicContact CD2-CD2 4.24Å; Q199-L203 VanDerWaalsContact O-CB 3.29Å; Q199-L203 WeakPolarHBondContact O-CB 3.33Å; Q199-L203 PolarHBondContact O-N 3.21Å; Y200-L203 PolarHBondContact O-N 2.97Å; L203-A205 VanDerWaalsContact C-N 3.3Å; L203-A205 PolarHBondContact O-N 2.61Å; L203-D206 PolarHBondContact O-N 3.29Å; L203-L207 HydrophobicContact CD1-CD1 3.76Å; L203-L207 HydrophobicContact CD1-CG 3.81Å; L203-L207 HydrophobicContact CG-CD1 3.83Å; L203-L207 HydrophobicContact CG-CG 4.31Å; L203-L207 WeakPolarHBondContact O-CB 3.32Å; L203-L207 WeakPolarHBondContact O-CG 3.38Å; L203-L207 PolarHBondContact O-N 3.37Å; L203-L251 HydrophobicContact CD2-CD2 3.66Å; L203-L254 HydrophobicContact CB-CD2 4.42Å; L203-L254 HydrophobicContact CD2-CD2 3.87Å; L203-L254 HydrophobicContact CG-CD2 3.9Å; L203-L255 HydrophobicContact CD2-CD2 4Å
204Q98.8Very high98.1Very high95 Ų9559.8 Ų59.844%0.44430%0.296SS..Hα-helixtrans-59.8-41.6174.8-175.6-178.8-12.500111.7Y200 W202 A208 L254Y200-Q204 PolarHBondContact O-N 2.79Å; W202-Q204 VanDerWaalsContact C-N 3.3Å; W202-Q204 PolarHBondContact O-N 2.95Å; Q204-A208 VanDerWaalsContact O-CB 3.22Å; Q204-A208 WeakPolarHBondContact O-CB 3.49Å; Q204-A208 PolarHBondContact O-N 2.91Å; Q204-A208 VanDerWaalsContact O-N 3.14Å; Q204-L254 HydrophobicContact CB-CD1 4.39Å; Q204-L254 HydrophobicContact CB-CD2 4.31Å; Q204-L254 HydrophobicContact CG-CD1 4.27Å
205A98.7Very high98.1Very high43 Ų4353.3 Ų53.336%0.35527%0.269SS..Hα-helixtrans-73.1-33.5178.500000112.9K201 W202 L203 K209K201-A205 PolarHBondContact O-N 2.83Å; W202-A205 CarbonylContact O-C 3.45Å; W202-A205 WeakPolarHBondContact O-CA 3.11Å; W202-A205 WeakPolarHBondContact O-CB 2.93Å; W202-A205 PolarHBondContact O-N 2.77Å; L203-A205 VanDerWaalsContact C-N 3.3Å; L203-A205 PolarHBondContact O-N 2.61Å; A205-K209 WeakPolarHBondContact O-CD 2.99Å; A205-K209 VanDerWaalsContact O-CG 3.28Å; A205-K209 WeakPolarHBondContact O-CG 3.48Å; A205-K209 PolarHBondContact O-N 3.13Å
206D98.8Very high98.2Very high24 Ų2451 Ų5113%0.12826%0.259CS..Hα-helixtrans-67.9-53.7177.5-172.363.7000110.5S172 H179 W202 L203 A208 K209 N210S172-D206 WeakPolarHBondContact CB-OD2 3.5Å; S172-D206 PolarHBondContact OG-OD1 3.03Å; S172-D206 PolarHBondContact OG-OD2 2.8Å; H179-D206 IonicContact CE1-OD1 3.44Å; H179-D206 IonicContact CE1-OD2 2.9Å; H179-D206 IonicContact NE2-OD1 3.64Å; H179-D206 IonicContact NE2-OD2 3.92Å; H179-D206 PolarHBondContact NE2-OD2 3.04Å; W202-D206 HydrophobicContact CZ2-CB 4.33Å; W202-D206 WeakPolarHBondContact O-CB 2.87Å; W202-D206 PolarHBondContact O-N 3.45Å; L203-D206 PolarHBondContact O-N 3.29Å; D206-A208 VanDerWaalsContact C-N 3.31Å; D206-A208 PolarHBondContact O-N 3.09Å; D206-K209 PolarHBondContact O-N 2.85Å; D206-N210 PolarHBondContact O-N 2.57Å
207L98.8Very high98.2Very high11 Ų1151 Ų516%0.05826%0.259CS..Hα-helixtrans-59.7-37.2175.5-70.6170.9000112.9I181 L203 K209 N210 T215 L254 L255 H258 V260I181-L207 HydrophobicContact CD1-CD2 3.62Å; I181-L207 HydrophobicContact CD1-CG 4.28Å; L203-L207 HydrophobicContact CD1-CD1 3.76Å; L203-L207 HydrophobicContact CD1-CG 3.81Å; L203-L207 HydrophobicContact CG-CD1 3.83Å; L203-L207 HydrophobicContact CG-CG 4.31Å; L203-L207 WeakPolarHBondContact O-CB 3.32Å; L203-L207 WeakPolarHBondContact O-CG 3.38Å; L203-L207 PolarHBondContact O-N 3.37Å; L207-K209 VanDerWaalsContact C-N 3.26Å; L207-K209 PolarHBondContact O-N 3.45Å; L207-N210 PolarHBondContact O-N 2.8Å; L207-T215 HydrophobicContact CD2-CG2 4.04Å; L207-L254 HydrophobicContact CD1-CD2 4.28Å; L207-L254 HydrophobicContact CD1-CG 4.03Å; L207-L255 HydrophobicContact CD1-CD2 4.1Å; L207-H258 HydrophobicContact CB-CB 4.2Å; L207-H258 HydrophobicContact CD1-CB 4.1Å; L207-H258 HydrophobicContact CD2-CB 4.33Å; L207-H258 HydrophobicContact CG-CB 4.46Å; L207-V260 HydrophobicContact CD2-CG2 4.23Å
208A98.4Very high98.2Very high75 Ų7547.5 Ų47.562%0.6224%0.242SC*.Hα-helixtrans-68.3-24.3177.400000113.5Q204 D206Q204-A208 VanDerWaalsContact O-CB 3.22Å; Q204-A208 WeakPolarHBondContact O-CB 3.49Å; Q204-A208 PolarHBondContact O-N 2.91Å; Q204-A208 VanDerWaalsContact O-N 3.14Å; D206-A208 VanDerWaalsContact C-N 3.31Å; D206-A208 PolarHBondContact O-N 3.09Å
209K97.7Very high98.2Very high162 Ų16246.7 Ų46.770%0.70424%0.235SC*.Hα-helixtrans-95-19.3178.2-71.1171.9-173.2171.80112.9A205 D206 L207 K211A205-K209 WeakPolarHBondContact O-CD 2.99Å; A205-K209 VanDerWaalsContact O-CG 3.28Å; A205-K209 WeakPolarHBondContact O-CG 3.48Å; A205-K209 PolarHBondContact O-N 3.13Å; D206-K209 PolarHBondContact O-N 2.85Å; L207-K209 VanDerWaalsContact C-N 3.26Å; L207-K209 PolarHBondContact O-N 3.45Å; K209-K211 WeakPolarHBondContact O-CG 3.16Å; K209-K211 PolarHBondContact O-N 3.26Å
210N98Very high98.2Very high35 Ų3546.7 Ų46.719%0.18724%0.235CC..  trans-56.9129.6-177.5179.317.3000111.3H179 D206 L207 A212 T215H179-N210 WeakPolarHBondContact CB-OD1 3.38Å; D206-N210 PolarHBondContact O-N 2.57Å; L207-N210 PolarHBondContact O-N 2.8Å; N210-A212 WeakPolarHBondContact OD1-CB 3.2Å; N210-A212 PolarHBondContact OD1-N 2.76Å; N210-T215 PolarHBondContact ND2-OG1 3.29Å
211K96.1Very high98.1Very high188 Ų18845.8 Ų45.882%0.81723%0.231SC*.  trans-124.14.1175.6-58.3-157.9-180-171.40113.2K209K209-K211 WeakPolarHBondContact O-CG 3.16Å; K209-K211 PolarHBondContact O-N 3.26Å
212A96.4Very high97.9Very high26 Ų2639.2 Ų39.222%0.21520%0.203CC..  trans-63.7155.3176.400000110.2H179 N210H179-A212 HydrophobicContact CB-CB 3.51Å; N210-A212 WeakPolarHBondContact OD1-CB 3.2Å; N210-A212 PolarHBondContact OD1-N 2.76Å
213Q95.8Very high97.7Very high89 Ų8937.9 Ų37.942%0.41620%0.198SC..SBendtrans-72.6-42.6179.1-62.9-62.9-49.300110.1L177 T338 K363L177-Q213 HydrophobicContact CB-CB 4.25Å; L177-Q213 HydrophobicContact CB-CG 4.46Å; L177-Q213 HydrophobicContact CD2-CG 4.17Å; L177-Q213 PolarHBondContact O-N 2.86Å; Q213-T338 HydrophobicContact CG-CG2 3.79Å; Q213-K363 WeakPolarHBondContact O-CE 3.3Å; Q213-K363 PolarHBondContact O-NZ 3.5Å
214W98.3Very high97.4Very high0 Ų038.1 Ų38.10%020%0.199CC..EExtended strand (participates in β ladder)trans-109.6137.1179.8-62.598.5000111L177 T178 H179 D261 V335 N337 T339 L341 L361 K363L177-W214 PolarHBondContact O-N 2.87Å; T178-W214 CarbonylContact C-O 3.53Å; T178-W214 WeakPolarHBondContact CA-O 3.44Å; T178-W214 HydrophobicContact CG2-CB 4Å; H179-W214 PolarHBondContact N-O 3.14Å; W214-D261 VanDerWaalsContact CA-OD2 3.29Å; W214-D261 WeakPolarHBondContact CA-OD2 3.39Å; W214-D261 HydrophobicContact CE3-CB 3.82Å; W214-D261 VanDerWaalsContact CE3-CG 3.43Å; W214-D261 HydrophobicContact CZ3-CB 4.19Å; W214-V335 HydrophobicContact CG-CG1 4.16Å; W214-N337 PolarHBondContact NE1-O 3.49Å; W214-T339 VanDerWaalsContact CZ2-C 3.43Å; W214-L341 HydrophobicContact CD2-CD2 3.61Å; W214-L341 HydrophobicContact CD2-CG 4.35Å; W214-L341 HydrophobicContact CE3-CD2 3.33Å; W214-L341 HydrophobicContact CE3-CG 4.1Å; W214-L341 HydrophobicContact CG-CD2 4.19Å; W214-L341 HydrophobicContact CH2-CD2 4.15Å; W214-L341 HydrophobicContact CH2-CG 4Å; W214-L341 HydrophobicContact CZ2-CB 4.34Å; W214-L341 HydrophobicContact CZ2-CD2 4.37Å; W214-L341 HydrophobicContact CZ2-CG 4.25Å; W214-L341 HydrophobicContact CZ3-CD2 3.64Å; W214-L341 HydrophobicContact CZ3-CG 3.94Å; W214-L361 HydrophobicContact CH2-CG 4.38Å; W214-L361 HydrophobicContact CZ3-CD2 3.88Å; W214-L361 HydrophobicContact CZ3-CG 4.02Å; W214-K363 HydrophobicContact CE3-CD 4.4Å; W214-K363 HydrophobicContact CH2-CD 3.98Å; W214-K363 HydrophobicContact CH2-CG 3.77Å; W214-K363 HydrophobicContact CZ2-CG 4.26Å; W214-K363 HydrophobicContact CZ3-CD 3.88Å; W214-K363 HydrophobicContact CZ3-CG 4.19Å
215T98.9Very high97Very high10 Ų1033.7 Ų33.76%0.06118%0.178CC..EExtended strand (participates in β ladder)trans-119.5119.3174.5-51.80000109.7I181 L207 N210 V217 V260 D261 M262I181-T215 HydrophobicContact CD1-CG2 4.16Å; L207-T215 HydrophobicContact CD2-CG2 4.04Å; N210-T215 PolarHBondContact ND2-OG1 3.29Å; T215-V217 HydrophobicContact CG2-CG2 4.49Å; T215-V260 HydrophobicContact CG2-CG2 3.98Å; T215-D261 PolarHBondContact N-OD2 3.1Å; T215-D261 PolarHBondContact O-N 3.17Å; T215-M262 PolarHBondContact O-N 3.15Å
216I98.9Very high96.6Very high0 Ų031.8 Ų31.80%016%0.162CC..EExtended strand (participates in β ladder)trans-122.1116.9-178.7-57.7-174.6000108.7T178 H179 F180 I181 M218 M262 L264 L333T178-I216 HydrophobicContact CG2-CB 4.43Å; T178-I216 HydrophobicContact CG2-CD1 3.84Å; T178-I216 HydrophobicContact CG2-CG1 3.9Å; H179-I216 PolarHBondContact O-N 3.23Å; F180-I216 WeakPolarHBondContact CA-O 3.42Å; F180-I216 HydrophobicContact CD1-CB 3.98Å; F180-I216 HydrophobicContact CD1-CG2 4.22Å; F180-I216 HydrophobicContact CE1-CB 4.09Å; F180-I216 HydrophobicContact CE1-CD1 3.89Å; F180-I216 HydrophobicContact CE1-CG1 4.46Å; F180-I216 HydrophobicContact CE1-CG2 4.26Å; F180-I216 HydrophobicContact CZ-CD1 4.38Å; I181-I216 PolarHBondContact N-O 2.8Å; I216-M218 HydrophobicContact CG2-CG 4.27Å; I216-M218 HydrophobicContact CG2-SD 4.36Å; I216-M262 WeakPolarHBondContact CA-O 3.2Å; I216-M262 HydrophobicContact CG1-CB 4.33Å; I216-M262 HydrophobicContact CG2-CB 4.43Å; I216-L264 HydrophobicContact CG2-CD1 3.41Å; I216-L264 VanDerWaalsContact CG2-CD1 3.41Å; I216-L333 HydrophobicContact CD1-CD1 4.32Å; I216-L333 HydrophobicContact CD1-CD2 3.4Å; I216-L333 VanDerWaalsContact CD1-CD2 3.4Å
217V98.9Very high95.7Very high0 Ų031.6 Ų31.60%016%0.162CC..EExtended strand (participates in β ladder)trans-104.5137.9179.1179.20000109.3I181 L183 T215 F219 L255 V260 M262 V263 L264I181-V217 HydrophobicContact CB-CG2 4.18Å; I181-V217 HydrophobicContact CD1-CG2 3.92Å; I181-V217 CarbonylContact O-C 3.42Å; L183-V217 HydrophobicContact CD1-CG1 3.73Å; L183-V217 HydrophobicContact CG-CG1 4.29Å; T215-V217 HydrophobicContact CG2-CG2 4.49Å; V217-F219 HydrophobicContact CG1-CD1 4.11Å; V217-F219 HydrophobicContact CG1-CE1 4.28Å; V217-L255 HydrophobicContact CB-CD1 4.25Å; V217-L255 HydrophobicContact CG1-CD1 3.95Å; V217-L255 HydrophobicContact CG1-CD2 4.4Å; V217-L255 HydrophobicContact CG2-CD1 4.4Å; V217-L255 HydrophobicContact CG2-CD2 4.11Å; V217-V260 HydrophobicContact CB-CG1 4.22Å; V217-V260 HydrophobicContact CG2-CB 4.48Å; V217-V260 HydrophobicContact CG2-CG1 3.74Å; V217-V260 HydrophobicContact CG2-CG2 3.86Å; V217-M262 PolarHBondContact N-O 3.41Å; V217-V263 HydrophobicContact CB-CG2 4.39Å; V217-V263 CarbonylContact O-C 3.6Å; V217-V263 WeakPolarHBondContact O-CA 3.29Å; V217-L264 PolarHBondContact O-N 3.03Å
218M98.8Very high94.4Very high0 Ų038.4 Ų38.40%019%0.191CC..EExtended strand (participates in β ladder)trans-134.1140-179.1-56.9147.9-63.100110.4I104 I106 F140 W171 F180 I181 G182 L183 I216 L264I104-M218 HydrophobicContact CB-SD 4.46Å; I104-M218 HydrophobicContact CD1-CE 4.21Å; I104-M218 HydrophobicContact CD1-SD 3.81Å; I104-M218 HydrophobicContact CG2-CE 4.41Å; I104-M218 HydrophobicContact CG2-SD 3.76Å; I106-M218 HydrophobicContact CG2-CB 4.08Å; I106-M218 HydrophobicContact CG2-CG 4.38Å; F140-M218 HydrophobicContact CE1-CB 3.62Å; F140-M218 HydrophobicContact CZ-CB 3.63Å; W171-M218 HydrophobicContact CH2-CE 4.49Å; F180-M218 HydrophobicContact CB-CE 3.92Å; F180-M218 HydrophobicContact CD1-CE 3.84Å; F180-M218 HydrophobicContact CD1-SD 4.21Å; F180-M218 HydrophobicContact CG-CE 4.36Å; I181-M218 VanDerWaalsContact O-CE 3.26Å; I181-M218 WeakPolarHBondContact O-CE 3.3Å; I181-M218 PolarHBondContact O-N 3.18Å; G182-M218 WeakPolarHBondContact CA-O 3.25Å; L183-M218 PolarHBondContact N-O 2.73Å; I216-M218 HydrophobicContact CG2-CG 4.27Å; I216-M218 HydrophobicContact CG2-SD 4.36Å; M218-L264 WeakPolarHBondContact CA-O 3.44Å; M218-L264 HydrophobicContact CG-CB 4.18Å; M218-L264 HydrophobicContact CG-CD1 4.48Å
219F98.1Very high93.4Very high2 Ų239.3 Ų39.31%0.00919%0.185CC..  trans-155.9166.117347.6-89.9000109.1F140 L183 V217 R221 W223 L255 V263 L264 Y265F140-F219 VanDerWaalsContact CE2-CA 3.49Å; L183-F219 HydrophobicContact CB-CB 4.15Å; L183-F219 HydrophobicContact CD1-CD1 4.44Å; L183-F219 WeakPolarHBondContact O-CB 3.22Å; V217-F219 HydrophobicContact CG1-CD1 4.11Å; V217-F219 HydrophobicContact CG1-CE1 4.28Å; F219-R221 WeakPolarHBondContact CD2-O 3.4Å; F219-R221 WeakPolarHBondContact CE2-O 3.24Å; F219-W223 HydrophobicContact CE1-CH2 4Å; F219-W223 AromaticContact CE1-CZ2 3.9Å; F219-W223 HydrophobicContact CE1-CZ2 3.9Å; F219-W223 AromaticContact CE2-CD1 3.94Å; F219-W223 HydrophobicContact CE2-CD2 4.06Å; F219-W223 AromaticContact CE2-CE2 3.6Å; F219-W223 HydrophobicContact CE2-CG 4.25Å; F219-W223 AromaticContact CE2-CZ2 3.96Å; F219-W223 HydrophobicContact CE2-CZ2 3.96Å; F219-W223 AromaticContact CE2-NE1 3.55Å; F219-W223 AromaticContact CZ-CD2 3.68Å; F219-W223 HydrophobicContact CZ-CD2 3.68Å; F219-W223 AromaticContact CZ-CE2 3.35Å; F219-W223 HydrophobicContact CZ-CE3 4Å; F219-W223 HydrophobicContact CZ-CG 4.3Å; F219-W223 AromaticContact CZ-CH2 3.72Å; F219-W223 HydrophobicContact CZ-CH2 3.72Å; F219-W223 AromaticContact CZ-CZ2 3.37Å; F219-W223 HydrophobicContact CZ-CZ2 3.37Å; F219-W223 HydrophobicContact CZ-CZ3 4.02Å; F219-W223 AromaticContact CZ-NE1 3.83Å; F219-L255 HydrophobicContact CE1-CD1 4.48Å; F219-V263 HydrophobicContact CD1-CG1 4.29Å; F219-V263 HydrophobicContact CE1-CG1 3.39Å; F219-V263 HydrophobicContact CZ-CG1 3.62Å; F219-L264 PolarHBondContact N-O 3.33Å; F219-Y265 HydrophobicContact CD2-CD1 4.46Å; F219-Y265 AromaticContact CE2-CD1 3.77Å; F219-Y265 HydrophobicContact CE2-CD1 3.77Å; F219-Y265 HydrophobicContact CZ-CD1 4.01Å; F219-Y265 WeakPolarHBondContact O-CA 3.32Å; F219-Y265 WeakPolarHBondContact O-CB 3.48Å
220H97.8Very high92.3Very high0 Ų038.4 Ų38.40%018%0.182CC..SBendtrans-80.7-52.2-167.6-176.768000113.1D78 I106 D108 F140 G142 N143 S185 G266 H267D78-H220 IonicContact OD1-CE1 3.17Å; D78-H220 IonicContact OD2-CE1 2.74Å; I106-H220 PolarHBondContact O-ND1 3.5Å; D108-H220 IonicContact OD1-CE1 3.01Å; D108-H220 IonicContact OD1-NE2 2.95Å; D108-H220 PolarHBondContact OD1-NE2 2.88Å; D108-H220 IonicContact OD2-CE1 3.27Å; D108-H220 PolarHBondContact OD2-CE1 3.32Å; D108-H220 VanDerWaalsContact OD2-CE1 3.31Å; D108-H220 IonicContact OD2-NE2 3.48Å; D108-H220 PolarHBondContact OD2-NE2 3.41Å; D108-H220 VanDerWaalsContact OD2-NE2 3.11Å; F140-H220 HydrophobicContact CE2-CB 4.39Å; G142-H220 WeakPolarHBondContact CA-CD2 3.19Å; N143-H220 PolarHBondContact OD1-NE2 3.05Å; S185-H220 WeakPolarHBondContact OG-CB 3.48Å; S185-H220 PolarHBondContact OG-N 2.82Å; H220-G266 CarbonylContact O-C 3.54Å; H220-G266 VanDerWaalsContact O-C 3.31Å; H220-G266 PolarHBondContact O-N 3.06Å; H220-H267 AromaticContact CD2-CG 3.92Å; H220-H267 AromaticContact CD2-ND1 3.81Å; H220-H267 VanDerWaalsContact CE1-CA 3.46Å; H220-H267 WeakPolarHBondContact CE1-CA 3.46Å; H220-H267 PolarHBondContact CE1-N 3.11Å; H220-H267 VanDerWaalsContact CE1-N 3.32Å; H220-H267 WeakPolarHBondContact NE2-CA 3.3Å; H220-H267 VanDerWaalsContact NE2-CB 3.32Å; H220-H267 WeakPolarHBondContact NE2-CB 3.45Å; H220-H267 AromaticContact NE2-CG 3.54Å; H220-H267 AromaticContact NE2-ND1 3.18Å; H220-H267 PolarHBondContact NE2-ND1 3.3Å; H220-H267 VanDerWaalsContact NE2-ND1 3.18Å; H220-H267 WeakPolarHBondContact O-CB 3.41Å
221R96.3Very high91.4Very high35 Ų3538.3 Ų38.313%0.13219%0.188CC..SBendtrans-80.1125.4-174.6-66.7179-178.3-84.8-0.4113.9N143 S185 E186 A189 F219 D238 H267N143-R221 VanDerWaalsContact CB-NH2 3.26Å; S185-R221 PolarHBondContact OG-N 3.43Å; S185-R221 VanDerWaalsContact OG-N 3.12Å; E186-R221 VanDerWaalsContact CD-NE 3.27Å; E186-R221 WeakPolarHBondContact OE1-CD 3.39Å; E186-R221 WeakPolarHBondContact OE1-CG 3.2Å; E186-R221 IonicContact OE1-CZ 3.77Å; E186-R221 IonicContact OE1-NE 2.71Å; E186-R221 PolarHBondContact OE1-NE 2.85Å; E186-R221 IonicContact OE2-CZ 3.82Å; E186-R221 VanDerWaalsContact OE2-CZ 3.22Å; E186-R221 IonicContact OE2-NE 3.5Å; E186-R221 PolarHBondContact OE2-NE 2.83Å; E186-R221 IonicContact OE2-NH2 3.53Å; E186-R221 PolarHBondContact OE2-NH2 3.37Å; A189-R221 VanDerWaalsContact CB-NE 3.27Å; F219-R221 WeakPolarHBondContact CD2-O 3.4Å; F219-R221 WeakPolarHBondContact CE2-O 3.24Å; R221-D238 WeakPolarHBondContact CD-OD1 3.38Å; R221-D238 IonicContact CZ-OD1 3.01Å; R221-D238 IonicContact NE-OD1 3.4Å; R221-D238 IonicContact NH1-OD1 2.74Å; R221-D238 PolarHBondContact NH1-OD1 2.76Å; R221-H267 PolarHBondContact NH1-NE2 3.1Å; R221-H267 VanDerWaalsContact NH1-NE2 3.13Å
222P95.3Very high90.7Very high0 Ų029.6 Ų29.60%015%0.152CC..  trans-74.5147.4-176.830.8-37.8000113.6G232 C233 Y265 K268 L301P222-G232 WeakPolarHBondContact CD-O 3.44Å; P222-G232 WeakPolarHBondContact CG-O 3.24Å; P222-C233 HydrophobicContact CG-CB 3.88Å; P222-Y265 HydrophobicContact CB-CD1 4.12Å; P222-Y265 HydrophobicContact CB-CD2 3.37Å; P222-Y265 HydrophobicContact CB-CE1 4.07Å; P222-Y265 HydrophobicContact CB-CE2 3.35Å; P222-Y265 HydrophobicContact CB-CG 3.78Å; P222-K268 HydrophobicContact CG-CG 4.12Å; P222-L301 HydrophobicContact CB-CD1 3.72Å; P222-L301 HydrophobicContact CG-CD1 3.92Å
223W94.5Very high89.8Confident1 Ų128.3 Ų28.30%0.00414%0.142CC..SBendtrans-94.3-22.2173.1-68.9-11.7000114.6F219 S241 R242 L251 E252 L255 Y299F219-W223 HydrophobicContact CE1-CH2 4Å; F219-W223 AromaticContact CE1-CZ2 3.9Å; F219-W223 HydrophobicContact CE1-CZ2 3.9Å; F219-W223 AromaticContact CE2-CD1 3.94Å; F219-W223 HydrophobicContact CE2-CD2 4.06Å; F219-W223 AromaticContact CE2-CE2 3.6Å; F219-W223 HydrophobicContact CE2-CG 4.25Å; F219-W223 AromaticContact CE2-CZ2 3.96Å; F219-W223 HydrophobicContact CE2-CZ2 3.96Å; F219-W223 AromaticContact CE2-NE1 3.55Å; F219-W223 AromaticContact CZ-CD2 3.68Å; F219-W223 HydrophobicContact CZ-CD2 3.68Å; F219-W223 AromaticContact CZ-CE2 3.35Å; F219-W223 HydrophobicContact CZ-CE3 4Å; F219-W223 HydrophobicContact CZ-CG 4.3Å; F219-W223 AromaticContact CZ-CH2 3.72Å; F219-W223 HydrophobicContact CZ-CH2 3.72Å; F219-W223 AromaticContact CZ-CZ2 3.37Å; F219-W223 HydrophobicContact CZ-CZ2 3.37Å; F219-W223 HydrophobicContact CZ-CZ3 4.02Å; F219-W223 AromaticContact CZ-NE1 3.83Å; W223-S241 PolarHBondContact NE1-OG 3.21Å; W223-R242 HydrophobicContact CB-CB 4.41Å; W223-R242 HydrophobicContact CB-CG 4.17Å; W223-R242 HydrophobicContact CD2-CB 3.76Å; W223-R242 HydrophobicContact CD2-CG 3.62Å; W223-R242 HydrophobicContact CE3-CB 4.44Å; W223-R242 HydrophobicContact CE3-CG 3.84Å; W223-R242 HydrophobicContact CG-CB 3.71Å; W223-R242 HydrophobicContact CG-CG 3.77Å; W223-L251 HydrophobicContact CH2-CB 3.66Å; W223-L251 HydrophobicContact CZ2-CB 3.66Å; W223-L251 HydrophobicContact CZ2-CD1 4.14Å; W223-E252 HydrophobicContact CE3-CB 4.12Å; W223-E252 HydrophobicContact CE3-CG 4.26Å; W223-E252 HydrophobicContact CH2-CB 4.06Å; W223-E252 HydrophobicContact CZ3-CB 3.64Å; W223-E252 HydrophobicContact CZ3-CG 3.97Å; W223-L255 HydrophobicContact CH2-CD1 3.77Å; W223-L255 HydrophobicContact CH2-CG 4.47Å; W223-L255 HydrophobicContact CZ3-CD1 4.11Å; W223-Y299 AromaticContact CE3-CE1 3.62Å; W223-Y299 HydrophobicContact CE3-CE1 3.62Å; W223-Y299 AromaticContact CZ3-CE1 3.97Å; W223-Y299 HydrophobicContact CZ3-CE1 3.97Å; W223-Y299 WeakPolarHBondContact CZ3-OH 3.43Å
224Y93.2Very high89.2Confident5 Ų526.9 Ų26.92%0.0214%0.137CC..  trans-136.4132.2-177.2-63.3-71.2000106.4R242 E252 Y265 M274 I277 D279 G280 Y299 F320Y224-R242 VanDerWaalsContact CZ-NH1 3.34Å; Y224-R242 PolarHBondContact OH-NH1 3.46Å; Y224-E252 WeakPolarHBondContact CE2-OE1 3.1Å; Y224-E252 PolarHBondContact OH-OE1 3.28Å; Y224-Y265 PolarHBondContact O-OH 2.92Å; Y224-M274 WeakPolarHBondContact O-CE 3.14Å; Y224-I277 HydrophobicContact CD1-CD1 3.65Å; Y224-I277 HydrophobicContact CD1-CG1 4.48Å; Y224-I277 HydrophobicContact CD2-CD1 4.43Å; Y224-I277 HydrophobicContact CD2-CG2 3.83Å; Y224-I277 HydrophobicContact CE1-CD1 3.37Å; Y224-I277 HydrophobicContact CE1-CG1 3.92Å; Y224-I277 HydrophobicContact CE2-CD1 4.22Å; Y224-I277 HydrophobicContact CE2-CG1 4.03Å; Y224-I277 HydrophobicContact CE2-CG2 3.81Å; Y224-I277 HydrophobicContact CG-CD1 4.18Å; Y224-I277 HydrophobicContact CG-CG2 4.41Å; Y224-D279 PolarHBondContact OH-N 2.81Å; Y224-G280 PolarHBondContact OH-N 3.45Å; Y224-Y299 HydrophobicContact CD2-CD1 4.32Å; Y224-Y299 HydrophobicContact CD2-CD2 4.49Å; Y224-Y299 HydrophobicContact CD2-CE1 4.34Å; Y224-Y299 HydrophobicContact CD2-CG 4.37Å; Y224-Y299 HydrophobicContact CE2-CE1 4.47Å; Y224-Y299 HydrophobicContact CE2-CE2 4.36Å; Y224-F320 HydrophobicContact CD1-CD1 4.32Å; Y224-F320 HydrophobicContact CD1-CE1 4.08Å; Y224-F320 HydrophobicContact CD1-CZ 4.23Å
225C89.8Confident88.8Confident1 Ų130 Ų301%0.00715%0.153CC..  trans-165.8169161.976.20000109T227 C233 E272 L301C225-T227 PolarHBondContact SG-OG1 2.82Å; C225-C233 VanDerWaalsContact CA-SG 3.51Å; C225-C233 HydrophobicContact CB-CB 4.14Å; C225-C233 WeakPolarHBondContact CB-SG 3.39Å; C225-C233 PolarHBondContact N-SG 3.21Å; C225-C233 WeakPolarHBondContact SG-CB 3.34Å; C225-C233 CovalentContact SG-SG 1.97Å; C225-C233 PolarHBondContact SG-SG 3.05Å; C225-E272 WeakPolarHBondContact CA-OE2 3.36Å; C225-L301 HydrophobicContact CB-CD1 3.91Å
226S89.5Confident88.4Confident4 Ų435.7 Ų35.73%0.02818%0.175CC..  trans-100.113.6-179.4-60.80000114.6E272 D315 Q318S226-E272 WeakPolarHBondContact CB-OE1 3.31Å; S226-E272 PolarHBondContact N-OE2 3.36Å; S226-E272 PolarHBondContact OG-OE1 3.48Å; S226-D315 WeakPolarHBondContact O-CB 3.32Å; S226-Q318 WeakPolarHBondContact OG-CB 3.41Å; S226-Q318 PolarHBondContact OG-N 3.23Å
227T80.4Confident88.1Confident19 Ų1939 Ų3912%0.11719%0.192CC..  trans-73.5137.4178.365.90000111C225 D229 N234 K268C225-T227 PolarHBondContact SG-OG1 2.82Å; T227-D229 PolarHBondContact OG1-O 3.32Å; T227-N234 PolarHBondContact O-ND2 3.47Å; T227-K268 HydrophobicContact CG2-CG 4.37Å; T227-K268 VanDerWaalsContact OG1-CE 3.23Å; T227-K268 WeakPolarHBondContact OG1-CE 3.44Å
228K71.7Confident87.7Confident154 Ų15439.4 Ų39.467%0.6719%0.194SC*.SBendtrans-68.9-35.1175.7-83.9-179.8-161.1131.90112.8K230 D315K228-K230 PolarHBondContact O-N 2.84Å; K228-D315 WeakPolarHBondContact CB-OD2 3.32Å; K228-D315 WeakPolarHBondContact CD-OD1 3.08Å; K228-D315 WeakPolarHBondContact CE-OD1 3.26Å; K228-D315 HydrophobicContact CG-CB 4.08Å; K228-D315 VanDerWaalsContact CG-CG 3.43Å; K228-D315 VanDerWaalsContact CG-OD1 3.32Å; K228-D315 WeakPolarHBondContact CG-OD1 3.11Å; K228-D315 PolarHBondContact N-OD2 3.47Å; K228-D315 IonicContact NZ-OD1 3.96Å; K228-D315 PolarHBondContact NZ-OD1 2.92Å
229D77.4Confident87.3Confident95 Ų9542 Ų4251%0.50821%0.207SC..  trans-61.6129.7174.1-176.117000108.9T227 G231 K268T227-D229 PolarHBondContact OG1-O 3.32Å; D229-G231 PolarHBondContact OD1-N 2.82Å; D229-K268 IonicContact OD2-NZ 2.88Å
230K74.3Confident87.2Confident143 Ų14342.1 Ų42.162%0.62221%0.208SC*.  trans-74.4-35.9177.6-67.9-172.1177.3-175.50110.8K228 G232 C233 N234 D235K228-K230 PolarHBondContact O-N 2.84Å; K230-G232 PolarHBondContact O-N 2.99Å; K230-C233 PolarHBondContact O-N 3.3Å; K230-N234 CarbonylContact O-C 3.55Å; K230-N234 PolarHBondContact O-N 1.97Å; K230-D235 PolarHBondContact O-N 3.34Å
231G78.9Confident87.2Confident32 Ų3242.2 Ų42.233%0.3321%0.208SC..THydrogen-bonded Turntrans-58.3128178.800000110.7D229 K268D229-G231 PolarHBondContact OD1-N 2.82Å; G231-K268 WeakPolarHBondContact O-CE 3.33Å; G231-K268 PolarHBondContact O-NZ 3.25Å
232G80.8Confident87.2Confident5 Ų542.3 Ų42.35%0.05221%0.209CC..THydrogen-bonded Turntrans80.99.5174.600000116.2P222 K230 D238 H267 K268P222-G232 WeakPolarHBondContact CD-O 3.44Å; P222-G232 WeakPolarHBondContact CG-O 3.24Å; K230-G232 PolarHBondContact O-N 2.99Å; G232-D238 VanDerWaalsContact CA-CG 3.5Å; G232-D238 WeakPolarHBondContact CA-OD2 3.34Å; G232-D238 PolarHBondContact N-OD2 3.31Å; G232-H267 WeakPolarHBondContact CA-CD2 3.23Å; G232-H267 WeakPolarHBondContact CA-NE2 2.85Å; G232-H267 PolarHBondContact O-CD2 3.1Å; G232-K268 WeakPolarHBondContact O-CG 3.16Å
233C79.1Confident87.2Confident0 Ų048.2 Ų48.20%023%0.234CC..THydrogen-bonded Turntrans-163.8-26.3174.7176.30000116P222 C225 K230 K268P222-C233 HydrophobicContact CG-CB 3.88Å; C225-C233 VanDerWaalsContact CA-SG 3.51Å; C225-C233 HydrophobicContact CB-CB 4.14Å; C225-C233 WeakPolarHBondContact CB-SG 3.39Å; C225-C233 PolarHBondContact N-SG 3.21Å; C225-C233 WeakPolarHBondContact SG-CB 3.34Å; C225-C233 CovalentContact SG-SG 1.97Å; C225-C233 PolarHBondContact SG-SG 3.05Å; K230-C233 PolarHBondContact O-N 3.3Å; C233-K268 HydrophobicContact CB-CD 4.39Å; C233-K268 HydrophobicContact CB-CG 3.95Å
234N83.4Confident87.3Confident59 Ų5949 Ų4932%0.31624%0.243SC..THydrogen-bonded Turntrans-129.910.1-179.2-62.5-69.1000112.6T227 K230 M239T227-N234 PolarHBondContact O-ND2 3.47Å; K230-N234 CarbonylContact O-C 3.55Å; K230-N234 PolarHBondContact O-N 1.97Å; N234-M239 VanDerWaalsContact O-CE 3.29Å; N234-M239 WeakPolarHBondContact O-CE 3.31Å
235D89.1Confident87.5Confident64 Ų6451.8 Ų51.834%0.34226%0.258SS..SBendtrans-77154.1171-168.9-97.1000110.8K230 L237 D238 M239K230-D235 PolarHBondContact O-N 3.34Å; D235-L237 VanDerWaalsContact C-N 3.31Å; D235-L237 PolarHBondContact O-N 3.34Å; D235-L237 PolarHBondContact OD1-N 2.82Å; D235-D238 HydrophobicContact CB-CB 4.33Å; D235-D238 VanDerWaalsContact CB-OD2 3.24Å; D235-D238 WeakPolarHBondContact CB-OD2 3.22Å; D235-D238 PolarHBondContact O-N 3.47Å; D235-M239 WeakPolarHBondContact O-CB 3.41Å; D235-M239 WeakPolarHBondContact O-CG 3.47Å; D235-M239 PolarHBondContact O-N 2.86Å
236Y91Very high87.7Confident131 Ų13157.5 Ų57.551%0.51430%0.298SS..Hα-helixtrans-57.8-43.8178.5170.5-100.3000112.1M239 L240 N245Y236-M239 PolarHBondContact O-N 2.96Å; Y236-L240 HydrophobicContact CE1-CD1 4.37Å; Y236-L240 HydrophobicContact CE1-CD2 4.26Å; Y236-L240 HydrophobicContact CE2-CD1 4.18Å; Y236-L240 WeakPolarHBondContact O-CB 3.18Å; Y236-L240 PolarHBondContact O-N 2.89Å; Y236-N245 PolarHBondContact OH-ND2 2.79Å
237L92Very high88Confident70 Ų7062.9 Ų62.937%0.36632%0.323SS..Hα-helixtrans-70-39.5-177.7-67.5177.7000111.9I191 D235 M239 L240I191-L237 HydrophobicContact CD1-CD2 3.76Å; I191-L237 HydrophobicContact CG1-CD2 4.46Å; D235-L237 VanDerWaalsContact C-N 3.31Å; D235-L237 PolarHBondContact O-N 3.34Å; D235-L237 PolarHBondContact OD1-N 2.82Å; L237-M239 VanDerWaalsContact C-N 3.32Å; L237-M239 PolarHBondContact O-N 2.87Å; L237-L240 HydrophobicContact CD2-CD2 4.39Å; L237-L240 WeakPolarHBondContact O-CB 3.44Å; L237-L240 PolarHBondContact O-N 3.42Å
238D89.6Confident88.8Confident8 Ų862.1 Ų62.14%0.04332%0.318CS..Hα-helixtrans-59.7-42.8174.8-72.2-57000112.2R221 G232 D235 H267R221-D238 WeakPolarHBondContact CD-OD1 3.38Å; R221-D238 IonicContact CZ-OD1 3.01Å; R221-D238 IonicContact NE-OD1 3.4Å; R221-D238 IonicContact NH1-OD1 2.74Å; R221-D238 PolarHBondContact NH1-OD1 2.76Å; G232-D238 VanDerWaalsContact CA-CG 3.5Å; G232-D238 WeakPolarHBondContact CA-OD2 3.34Å; G232-D238 PolarHBondContact N-OD2 3.31Å; D235-D238 HydrophobicContact CB-CB 4.33Å; D235-D238 VanDerWaalsContact CB-OD2 3.24Å; D235-D238 WeakPolarHBondContact CB-OD2 3.22Å; D235-D238 PolarHBondContact O-N 3.47Å; D238-H267 IonicContact OD1-NE2 2.61Å
239M91.3Very high90Very high54 Ų5456.2 Ų56.227%0.26630%0.296SS..Hα-helixtrans-88-3.7-177.7-64.5-170.7-62.900113.7N234 D235 Y236 L237 S241 R242N234-M239 VanDerWaalsContact O-CE 3.29Å; N234-M239 WeakPolarHBondContact O-CE 3.31Å; D235-M239 WeakPolarHBondContact O-CB 3.41Å; D235-M239 WeakPolarHBondContact O-CG 3.47Å; D235-M239 PolarHBondContact O-N 2.86Å; Y236-M239 PolarHBondContact O-N 2.96Å; L237-M239 VanDerWaalsContact C-N 3.32Å; L237-M239 PolarHBondContact O-N 2.87Å; M239-S241 PolarHBondContact O-N 3.34Å; M239-R242 WeakPolarHBondContact O-CB 3.41Å; M239-R242 PolarHBondContact O-N 2.91Å
240L95.7Very high91Very high5 Ų552.4 Ų52.43%0.02628%0.279CS..Hα-helixtrans-60.6-36.5-172.4-174.851000111.7I191 Y236 L237 R242 G244 N245 L248I191-L240 HydrophobicContact CD1-CD2 3.49Å; I191-L240 VanDerWaalsContact CD1-CD2 3.49Å; Y236-L240 HydrophobicContact CE1-CD1 4.37Å; Y236-L240 HydrophobicContact CE1-CD2 4.26Å; Y236-L240 HydrophobicContact CE2-CD1 4.18Å; Y236-L240 WeakPolarHBondContact O-CB 3.18Å; Y236-L240 PolarHBondContact O-N 2.89Å; L237-L240 HydrophobicContact CD2-CD2 4.39Å; L237-L240 WeakPolarHBondContact O-CB 3.44Å; L237-L240 PolarHBondContact O-N 3.42Å; L240-R242 PolarHBondContact O-N 2.79Å; L240-G244 WeakPolarHBondContact O-CA 3.27Å; L240-G244 PolarHBondContact O-N 3.12Å; L240-N245 HydrophobicContact CD1-CB 4.04Å; L240-L248 HydrophobicContact CD2-CD1 3.51Å; L240-L248 HydrophobicContact CG-CD1 3.95Å
241S97.1Very high92.2Very high2 Ų245.8 Ų45.81%0.01425%0.25CC..Hα-helixtrans-63.9-22.2175.662.50000113.6Y188 W223 M239 L251Y188-S241 VanDerWaalsContact CG-CB 3.43Å; W223-S241 PolarHBondContact NE1-OG 3.21Å; M239-S241 PolarHBondContact O-N 3.34Å; S241-L251 WeakPolarHBondContact O-CB 3.11Å; S241-L251 WeakPolarHBondContact O-CG 3.37Å; S241-L251 PolarHBondContact O-N 3.02Å
242R97.2Very high93.1Very high37 Ų3744.5 Ų44.514%0.1424%0.235CC..Hα-helixtrans-68.6-61.1-179.6-166.6179.488.7-178.6-4.1111.8W223 Y224 M239 L240 G250 L251 E252W223-R242 HydrophobicContact CB-CB 4.41Å; W223-R242 HydrophobicContact CB-CG 4.17Å; W223-R242 HydrophobicContact CD2-CB 3.76Å; W223-R242 HydrophobicContact CD2-CG 3.62Å; W223-R242 HydrophobicContact CE3-CB 4.44Å; W223-R242 HydrophobicContact CE3-CG 3.84Å; W223-R242 HydrophobicContact CG-CB 3.71Å; W223-R242 HydrophobicContact CG-CG 3.77Å; Y224-R242 VanDerWaalsContact CZ-NH1 3.34Å; Y224-R242 PolarHBondContact OH-NH1 3.46Å; M239-R242 WeakPolarHBondContact O-CB 3.41Å; M239-R242 PolarHBondContact O-N 2.91Å; L240-R242 PolarHBondContact O-N 2.79Å; R242-G250 CarbonylContact O-C 3.49Å; R242-G250 WeakPolarHBondContact O-CA 3.5Å; R242-L251 PolarHBondContact O-N 3.17Å; R242-E252 VanDerWaalsContact CD-OE2 3.3Å; R242-E252 WeakPolarHBondContact CD-OE2 3.12Å; R242-E252 HydrophobicContact CG-CB 3.71Å; R242-E252 HydrophobicContact CG-CG 4.2Å; R242-E252 WeakPolarHBondContact CG-OE2 3.48Å; R242-E252 IonicContact NE-OE2 3.52Å; R242-E252 PolarHBondContact NE-OE2 3.43Å; R242-E252 VanDerWaalsContact O-CB 3.31Å; R242-E252 WeakPolarHBondContact O-CB 3.39Å; R242-E252 PolarHBondContact O-N 2.97Å; R242-E252 VanDerWaalsContact O-N 3.08Å
243K96Very high93.9Very high124 Ų12449.6 Ų49.654%0.53926%0.256SS..Hα-helixtrans-101.8-20.2-174.1-69.2-167.5168.1-169.50113.8D279K243-D279 WeakPolarHBondContact CE-OD1 3.29Å; K243-D279 IonicContact NZ-OD1 3.86Å; K243-D279 PolarHBondContact NZ-OD1 3.48Å
244G96.3Very high94.9Very high18 Ų1850 Ų5019%0.18626%0.258CS..BIsolated β-bridgetrans70.4-170.3-171.600000112.7L240 L248L240-G244 WeakPolarHBondContact O-CA 3.27Å; L240-G244 PolarHBondContact O-N 3.12Å; G244-L248 CarbonylContact C-O 3.25Å; G244-L248 WeakPolarHBondContact CA-O 3.33Å
245N95.9Very high95.6Very high62 Ų6247.2 Ų47.233%0.33224%0.243SC..  trans-145.8-158.2173.466.119.2000109.5Y236 L240 E247 L248Y236-N245 PolarHBondContact OH-ND2 2.79Å; L240-N245 HydrophobicContact CD1-CB 4.04Å; N245-E247 PolarHBondContact O-N 3.06Å; N245-E247 PolarHBondContact OD1-N 3.05Å; N245-L248 PolarHBondContact N-O 2.9Å; N245-L248 PolarHBondContact OD1-N 3.18Å
246S95.1Very high96.1Very high122 Ų12246.9 Ų46.985%0.85324%0.239SC*.SBendtrans-64.2-21.6178.9500000114.8
247E95.4Very high96.4Very high116 Ų11644.7 Ų44.754%0.54224%0.236SC..SBendtrans-114.9-30.4-174.1-60.3-173.9174.100113.2T193 Q197 N245T193-E247 HydrophobicContact CG2-CB 4.3Å; Q197-E247 PolarHBondContact NE2-O 2.62Å; N245-E247 PolarHBondContact O-N 3.06Å; N245-E247 PolarHBondContact OD1-N 3.05Å
248L97Very high96.7Very high3 Ų344.6 Ų44.62%0.01623%0.234CC..SBendtrans-109.4128.4-176-68170.7000110.5Y188 I191 T193 A196 L240 G244 N245Y188-L248 HydrophobicContact CD1-CB 4.31Å; Y188-L248 HydrophobicContact CD1-CD1 4.41Å; Y188-L248 HydrophobicContact CD1-CD2 4.48Å; Y188-L248 HydrophobicContact CE1-CB 4.39Å; I191-L248 HydrophobicContact CD1-CD1 4.29Å; T193-L248 HydrophobicContact CG2-CD2 4.18Å; A196-L248 HydrophobicContact CB-CD2 3.46Å; A196-L248 VanDerWaalsContact CB-CD2 3.46Å; L240-L248 HydrophobicContact CD2-CD1 3.51Å; L240-L248 HydrophobicContact CG-CD1 3.95Å; G244-L248 CarbonylContact C-O 3.25Å; G244-L248 WeakPolarHBondContact CA-O 3.33Å; N245-L248 PolarHBondContact N-O 2.9Å; N245-L248 PolarHBondContact OD1-N 3.18Å
249P97.9Very high97.1Very high31 Ų3152.4 Ų52.420%0.20127%0.267CS..BIsolated β-bridgetrans-77.8138.4179.732.9-35.7000111.7Y188 Y200Y188-P249 VanDerWaalsContact CE1-O 3.24Å; Y188-P249 WeakPolarHBondContact CE1-O 3.49Å; Y188-P249 PolarHBondContact OH-O 3.25Å; Y200-P249 VanDerWaalsContact CB-CG 3.41Å; Y200-P249 HydrophobicContact CD1-CB 3.97Å; Y200-P249 HydrophobicContact CD1-CG 3.94Å; Y200-P249 HydrophobicContact CD2-CB 3.5Å; Y200-P249 VanDerWaalsContact CD2-CB 3.5Å; Y200-P249 HydrophobicContact CD2-CG 3.51Å; Y200-P249 HydrophobicContact CE1-CB 4.17Å; Y200-P249 HydrophobicContact CE2-CB 3.72Å; Y200-P249 HydrophobicContact CE2-CG 4.26Å; Y200-P249 HydrophobicContact CG-CB 3.64Å; Y200-P249 HydrophobicContact CG-CG 3.32Å
250G97.9Very high97.5Very high15 Ų1550 Ų5016%0.15526%0.256CS..  trans-77.1134.917500000112.8Y200 R242Y200-G250 WeakPolarHBondContact CE2-O 3.34Å; R242-G250 CarbonylContact O-C 3.49Å; R242-G250 WeakPolarHBondContact O-CA 3.5Å
251L98.6Very high97.6Very high3 Ų350.8 Ų50.82%0.01626%0.26CS..Hα-helixtrans-83.5-33.5-177.6-64.4171.8000112.8L183 Y188 Y200 L203 W223 S241 R242 K253 L254 L255L183-L251 HydrophobicContact CD1-CD1 4.2Å; Y188-L251 HydrophobicContact CE2-CD1 3.9Å; Y188-L251 HydrophobicContact CE2-CG 4.42Å; Y188-L251 WeakPolarHBondContact OH-CD2 3.44Å; Y200-L251 HydrophobicContact CD2-CD2 3.9Å; L203-L251 HydrophobicContact CD2-CD2 3.66Å; W223-L251 HydrophobicContact CH2-CB 3.66Å; W223-L251 HydrophobicContact CZ2-CB 3.66Å; W223-L251 HydrophobicContact CZ2-CD1 4.14Å; S241-L251 WeakPolarHBondContact O-CB 3.11Å; S241-L251 WeakPolarHBondContact O-CG 3.37Å; S241-L251 PolarHBondContact O-N 3.02Å; R242-L251 PolarHBondContact O-N 3.17Å; L251-K253 VanDerWaalsContact C-N 3.34Å; L251-K253 PolarHBondContact O-N 3.44Å; L251-L254 WeakPolarHBondContact O-CB 3.26Å; L251-L254 PolarHBondContact O-N 3.06Å; L251-L255 WeakPolarHBondContact O-CG 3.41Å; L251-L255 PolarHBondContact O-N 3.41Å
252E98.6Very high97.7Very high5 Ų550.7 Ų50.72%0.02326%0.259CS..Hα-helixtrans-57.8-45.6-168.5-176.5178.2-152.600112.6W223 Y224 R242 L254 L255 F256 Y278 D279W223-E252 HydrophobicContact CE3-CB 4.12Å; W223-E252 HydrophobicContact CE3-CG 4.26Å; W223-E252 HydrophobicContact CH2-CB 4.06Å; W223-E252 HydrophobicContact CZ3-CB 3.64Å; W223-E252 HydrophobicContact CZ3-CG 3.97Å; Y224-E252 WeakPolarHBondContact CE2-OE1 3.1Å; Y224-E252 PolarHBondContact OH-OE1 3.28Å; R242-E252 VanDerWaalsContact CD-OE2 3.3Å; R242-E252 WeakPolarHBondContact CD-OE2 3.12Å; R242-E252 HydrophobicContact CG-CB 3.71Å; R242-E252 HydrophobicContact CG-CG 4.2Å; R242-E252 WeakPolarHBondContact CG-OE2 3.48Å; R242-E252 IonicContact NE-OE2 3.52Å; R242-E252 PolarHBondContact NE-OE2 3.43Å; R242-E252 VanDerWaalsContact O-CB 3.31Å; R242-E252 WeakPolarHBondContact O-CB 3.39Å; R242-E252 PolarHBondContact O-N 2.97Å; R242-E252 VanDerWaalsContact O-N 3.08Å; E252-L254 VanDerWaalsContact C-N 3.32Å; E252-L254 PolarHBondContact O-N 3.41Å; E252-L255 PolarHBondContact O-N 2.88Å; E252-F256 WeakPolarHBondContact O-CB 3.48Å; E252-F256 PolarHBondContact O-N 3.34Å; E252-Y278 HydrophobicContact CG-CD2 4.03Å; E252-Y278 HydrophobicContact CG-CE2 4.18Å; E252-D279 PolarHBondContact OE1-N 2.94Å; E252-D279 VanDerWaalsContact OE1-N 3.09Å
253K98.5Very high97.8Very high112 Ų11249 Ų4949%0.48725%0.253SS..Hα-helixtrans-61.6-42.3177.6-169.8-174.4-172.3-420111.7L251 F256 D257L251-K253 VanDerWaalsContact C-N 3.34Å; L251-K253 PolarHBondContact O-N 3.44Å; K253-F256 PolarHBondContact O-N 3.17Å; K253-D257 IonicContact NZ-OD1 2.65Å; K253-D257 PolarHBondContact NZ-OD1 2.98Å; K253-D257 IonicContact NZ-OD2 2.83Å; K253-D257 PolarHBondContact NZ-OD2 2.87Å; K253-D257 WeakPolarHBondContact O-CB 2.99Å; K253-D257 PolarHBondContact O-N 3.3Å
254L98.7Very high97.9Very high9 Ų943.1 Ų43.15%0.04723%0.227CC..Hα-helixtrans-62.6-44.2179.4-179.367.5000111.3Y200 L203 Q204 L207 L251 E252 H258Y200-L254 HydrophobicContact CD2-CD2 4.17Å; Y200-L254 HydrophobicContact CE2-CB 4.15Å; Y200-L254 HydrophobicContact CE2-CD2 3.73Å; Y200-L254 HydrophobicContact CE2-CG 4.5Å; L203-L254 HydrophobicContact CB-CD2 4.42Å; L203-L254 HydrophobicContact CD2-CD2 3.87Å; L203-L254 HydrophobicContact CG-CD2 3.9Å; Q204-L254 HydrophobicContact CB-CD1 4.39Å; Q204-L254 HydrophobicContact CB-CD2 4.31Å; Q204-L254 HydrophobicContact CG-CD1 4.27Å; L207-L254 HydrophobicContact CD1-CD2 4.28Å; L207-L254 HydrophobicContact CD1-CG 4.03Å; L251-L254 WeakPolarHBondContact O-CB 3.26Å; L251-L254 PolarHBondContact O-N 3.06Å; E252-L254 VanDerWaalsContact C-N 3.32Å; E252-L254 PolarHBondContact O-N 3.41Å; L254-H258 WeakPolarHBondContact CD1-CE1 3.47Å; L254-H258 PolarHBondContact O-N 3.11Å; L254-H258 PolarHBondContact O-ND1 3.21Å
255L98.8Very high97.9Very high0 Ų042.3 Ų42.30%022%0.219CC..Hα-helixtrans-65.6-40.9178.2-56.2-167000111.6L203 L207 V217 F219 W223 L251 E252 H258 K259 V260 V263L203-L255 HydrophobicContact CD2-CD2 4Å; L207-L255 HydrophobicContact CD1-CD2 4.1Å; V217-L255 HydrophobicContact CB-CD1 4.25Å; V217-L255 HydrophobicContact CG1-CD1 3.95Å; V217-L255 HydrophobicContact CG1-CD2 4.4Å; V217-L255 HydrophobicContact CG2-CD1 4.4Å; V217-L255 HydrophobicContact CG2-CD2 4.11Å; F219-L255 HydrophobicContact CE1-CD1 4.48Å; W223-L255 HydrophobicContact CH2-CD1 3.77Å; W223-L255 HydrophobicContact CH2-CG 4.47Å; W223-L255 HydrophobicContact CZ3-CD1 4.11Å; L251-L255 WeakPolarHBondContact O-CG 3.41Å; L251-L255 PolarHBondContact O-N 3.41Å; E252-L255 PolarHBondContact O-N 2.88Å; L255-H258 PolarHBondContact O-N 3.35Å; L255-K259 PolarHBondContact O-N 3.28Å; L255-V260 HydrophobicContact CB-CB 4.2Å; L255-V260 HydrophobicContact CB-CG2 3.88Å; L255-V260 HydrophobicContact CD2-CG2 4.18Å; L255-V260 WeakPolarHBondContact O-CG2 3.01Å; L255-V260 PolarHBondContact O-N 3.44Å; L255-V260 VanDerWaalsContact O-N 3.07Å; L255-V263 HydrophobicContact CD1-CG2 4.01Å
256F98.7Very high97.9Very high57 Ų5739.3 Ų39.325%0.2520%0.203CC..Hα-helixtrans-63.9-48.8176.4178.4-96.3000112.2E252 K253 H258 K259 Y278 K295 A296E252-F256 WeakPolarHBondContact O-CB 3.48Å; E252-F256 PolarHBondContact O-N 3.34Å; K253-F256 PolarHBondContact O-N 3.17Å; F256-H258 PolarHBondContact O-N 3.15Å; F256-K259 PolarHBondContact O-N 3.47Å; F256-Y278 HydrophobicContact CB-CD2 3.54Å; F256-Y278 HydrophobicContact CB-CE2 3.56Å; F256-Y278 HydrophobicContact CB-CG 4.39Å; F256-Y278 HydrophobicContact CD1-CD1 4.42Å; F256-Y278 HydrophobicContact CD1-CD2 4.14Å; F256-Y278 HydrophobicContact CD1-CE1 4.24Å; F256-Y278 AromaticContact CD1-CE2 3.94Å; F256-Y278 HydrophobicContact CD1-CE2 3.94Å; F256-Y278 HydrophobicContact CD1-CG 4.36Å; F256-Y278 AromaticContact CD1-CZ 3.99Å; F256-Y278 HydrophobicContact CD2-CD1 4.17Å; F256-Y278 AromaticContact CD2-CD2 3.55Å; F256-Y278 HydrophobicContact CD2-CD2 3.55Å; F256-Y278 HydrophobicContact CD2-CE2 4.19Å; F256-Y278 AromaticContact CD2-CG 3.52Å; F256-Y278 HydrophobicContact CD2-CG 3.52Å; F256-Y278 HydrophobicContact CE1-CD1 4.34Å; F256-Y278 HydrophobicContact CE1-CE1 4.27Å; F256-Y278 HydrophobicContact CE2-CD1 4.07Å; F256-Y278 HydrophobicContact CE2-CD2 4.27Å; F256-Y278 AromaticContact CE2-CG 3.79Å; F256-Y278 HydrophobicContact CE2-CG 3.79Å; F256-Y278 HydrophobicContact CG-CD1 4.33Å; F256-Y278 AromaticContact CG-CD2 3.46Å; F256-Y278 HydrophobicContact CG-CD2 3.46Å; F256-Y278 VanDerWaalsContact CG-CD2 3.46Å; F256-Y278 HydrophobicContact CG-CE1 4.48Å; F256-Y278 AromaticContact CG-CE2 3.63Å; F256-Y278 HydrophobicContact CG-CE2 3.63Å; F256-Y278 AromaticContact CG-CG 3.83Å; F256-Y278 HydrophobicContact CG-CG 3.83Å; F256-Y278 HydrophobicContact CZ-CD1 4.16Å; F256-Y278 HydrophobicContact CZ-CG 4.32Å; F256-K295 VanDerWaalsContact CE2-O 3.26Å; F256-K295 WeakPolarHBondContact CE2-O 3.26Å; F256-A296 HydrophobicContact CD2-CB 4.08Å; F256-A296 HydrophobicContact CE2-CB 3.98Å
257D98.5Very high97.9Very high86 Ų8634.8 Ų34.846%0.4617%0.168SC..Hα-helixtrans-60.5-33.5-179.6-71-13.9000111.8K253 K259K253-D257 IonicContact NZ-OD1 2.65Å; K253-D257 PolarHBondContact NZ-OD1 2.98Å; K253-D257 IonicContact NZ-OD2 2.83Å; K253-D257 PolarHBondContact NZ-OD2 2.87Å; K253-D257 WeakPolarHBondContact O-CB 2.99Å; K253-D257 PolarHBondContact O-N 3.3Å; D257-K259 VanDerWaalsContact C-N 3.32Å
258H98.6Very high97.7Very high68 Ų6829.6 Ų29.632%0.31514%0.144SC..THydrogen-bonded Turntrans-88.67.9176.6-69.583.7000114L207 L254 L255 F256 V260L207-H258 HydrophobicContact CB-CB 4.2Å; L207-H258 HydrophobicContact CD1-CB 4.1Å; L207-H258 HydrophobicContact CD2-CB 4.33Å; L207-H258 HydrophobicContact CG-CB 4.46Å; L254-H258 WeakPolarHBondContact CD1-CE1 3.47Å; L254-H258 PolarHBondContact O-N 3.11Å; L254-H258 PolarHBondContact O-ND1 3.21Å; L255-H258 PolarHBondContact O-N 3.35Å; F256-H258 PolarHBondContact O-N 3.15Å; H258-V260 VanDerWaalsContact C-N 3.31Å; H258-V260 PolarHBondContact O-N 2.96Å
259K98Very high97.5Very high172 Ų17230.3 Ų30.375%0.74815%0.147SC*.THydrogen-bonded Turntrans55.243176-50.2-174178.9-1630113.4L255 F256 D257 D261L255-K259 PolarHBondContact O-N 3.28Å; F256-K259 PolarHBondContact O-N 3.47Å; D257-K259 VanDerWaalsContact C-N 3.32Å; K259-D261 PolarHBondContact O-N 2.83Å
260V98.8Very high97.2Very high3 Ų329.1 Ų29.12%0.01814%0.139CC..  trans-54.3133.4170.8170.40000109.4L207 T215 V217 L255 H258 M262 V263 P297L207-V260 HydrophobicContact CD2-CG2 4.23Å; T215-V260 HydrophobicContact CG2-CG2 3.98Å; V217-V260 HydrophobicContact CB-CG1 4.22Å; V217-V260 HydrophobicContact CG2-CB 4.48Å; V217-V260 HydrophobicContact CG2-CG1 3.74Å; V217-V260 HydrophobicContact CG2-CG2 3.86Å; L255-V260 HydrophobicContact CB-CB 4.2Å; L255-V260 HydrophobicContact CB-CG2 3.88Å; L255-V260 HydrophobicContact CD2-CG2 4.18Å; L255-V260 WeakPolarHBondContact O-CG2 3.01Å; L255-V260 PolarHBondContact O-N 3.44Å; L255-V260 VanDerWaalsContact O-N 3.07Å; H258-V260 VanDerWaalsContact C-N 3.31Å; H258-V260 PolarHBondContact O-N 2.96Å; V260-M262 WeakPolarHBondContact CG1-O 3.08Å; V260-V263 HydrophobicContact CG1-CG2 4.03Å; V260-P297 HydrophobicContact CB-CG 4.19Å; V260-P297 HydrophobicContact CG1-CB 4.42Å; V260-P297 WeakPolarHBondContact O-CA 3.23Å; V260-P297 WeakPolarHBondContact O-CB 3.11Å; V260-P297 VanDerWaalsContact O-CG 3.28Å; V260-P297 WeakPolarHBondContact O-CG 3.26Å
261D98.8Very high97Very high21 Ų2128.4 Ų28.411%0.11213%0.132CC..  trans-81.3-45.4-174.4-63.1-76.3000111.4W214 T215 K259 V298 L361 K363W214-D261 VanDerWaalsContact CA-OD2 3.29Å; W214-D261 WeakPolarHBondContact CA-OD2 3.39Å; W214-D261 HydrophobicContact CE3-CB 3.82Å; W214-D261 VanDerWaalsContact CE3-CG 3.43Å; W214-D261 HydrophobicContact CZ3-CB 4.19Å; T215-D261 PolarHBondContact N-OD2 3.1Å; T215-D261 PolarHBondContact O-N 3.17Å; K259-D261 PolarHBondContact O-N 2.83Å; D261-V298 PolarHBondContact O-N 3.03Å; D261-L361 HydrophobicContact CB-CD2 4.1Å; D261-K363 IonicContact OD1-NZ 3.41Å; D261-K363 PolarHBondContact OD1-NZ 2.8Å; D261-K363 IonicContact OD2-NZ 3.21Å; D261-K363 PolarHBondContact OD2-NZ 3.21Å
262M98.6Very high96.9Very high1 Ų128.4 Ų28.41%0.00513%0.131CC..EExtended strand (participates in β ladder)trans-138.5145.6-177.5-61.1-174.268.500112T215 I216 V217 V260 L264 V298 I300 L341 T343 F359 L361T215-M262 PolarHBondContact O-N 3.15Å; I216-M262 WeakPolarHBondContact CA-O 3.2Å; I216-M262 HydrophobicContact CG1-CB 4.33Å; I216-M262 HydrophobicContact CG2-CB 4.43Å; V217-M262 PolarHBondContact N-O 3.41Å; V260-M262 WeakPolarHBondContact CG1-O 3.08Å; M262-L264 HydrophobicContact CB-CD1 4.12Å; M262-L264 HydrophobicContact CE-CD1 4.45Å; M262-V298 CarbonylContact C-O 3.49Å; M262-V298 VanDerWaalsContact CA-O 3.26Å; M262-V298 WeakPolarHBondContact CA-O 3.42Å; M262-I300 HydrophobicContact CE-CD1 3.36Å; M262-I300 HydrophobicContact CE-CG1 4.06Å; M262-L341 HydrophobicContact SD-CD1 3.61Å; M262-L341 HydrophobicContact SD-CD2 4.02Å; M262-T343 HydrophobicContact CE-CG2 3.79Å; M262-T343 HydrophobicContact SD-CG2 4.39Å; M262-F359 HydrophobicContact CE-CE1 4.43Å; M262-L361 HydrophobicContact CG-CD2 3.88Å; M262-L361 HydrophobicContact SD-CD2 4.42Å
263V98.8Very high96.8Very high0 Ų028.2 Ų28.20%013%0.131CC..EExtended strand (participates in β ladder)trans-123.1128.9169.2178.40000108.8V217 F219 L255 V260 Y265 P297 V298 Y299 I300V217-V263 HydrophobicContact CB-CG2 4.39Å; V217-V263 CarbonylContact O-C 3.6Å; V217-V263 WeakPolarHBondContact O-CA 3.29Å; F219-V263 HydrophobicContact CD1-CG1 4.29Å; F219-V263 HydrophobicContact CE1-CG1 3.39Å; F219-V263 HydrophobicContact CZ-CG1 3.62Å; L255-V263 HydrophobicContact CD1-CG2 4.01Å; V260-V263 HydrophobicContact CG1-CG2 4.03Å; V263-Y265 HydrophobicContact CG1-CD1 4.17Å; V263-Y265 HydrophobicContact CG1-CE1 4.47Å; V263-P297 HydrophobicContact CG2-CB 4.03Å; V263-V298 PolarHBondContact N-O 3.29Å; V263-Y299 HydrophobicContact CB-CD1 3.47Å; V263-Y299 VanDerWaalsContact CB-CD1 3.47Å; V263-Y299 HydrophobicContact CB-CE1 3.53Å; V263-Y299 HydrophobicContact CB-CG 4.15Å; V263-Y299 HydrophobicContact CG1-CD1 3.63Å; V263-Y299 HydrophobicContact CG1-CE1 3.62Å; V263-Y299 HydrophobicContact CG2-CD1 4.2Å; V263-Y299 HydrophobicContact CG2-CE1 3.75Å; V263-Y299 CarbonylContact O-C 3.55Å; V263-Y299 VanDerWaalsContact O-CA 3.27Å; V263-Y299 WeakPolarHBondContact O-CA 3.21Å; V263-I300 PolarHBondContact O-N 3.45Å
264L98.7Very high96.7Very high2 Ų223 Ų231%0.0111%0.108CC..EExtended strand (participates in β ladder)trans-122.1137.3176.2-59.989.8000110.9I75 I216 V217 M218 F219 M262 I300 T302 T331I75-L264 HydrophobicContact CB-CD2 4.29Å; I75-L264 HydrophobicContact CD1-CD2 4.06Å; I75-L264 HydrophobicContact CG2-CD2 4.03Å; I216-L264 HydrophobicContact CG2-CD1 3.41Å; I216-L264 VanDerWaalsContact CG2-CD1 3.41Å; V217-L264 PolarHBondContact O-N 3.03Å; M218-L264 WeakPolarHBondContact CA-O 3.44Å; M218-L264 HydrophobicContact CG-CB 4.18Å; M218-L264 HydrophobicContact CG-CD1 4.48Å; F219-L264 PolarHBondContact N-O 3.33Å; M262-L264 HydrophobicContact CB-CD1 4.12Å; M262-L264 HydrophobicContact CE-CD1 4.45Å; L264-I300 VanDerWaalsContact CA-O 3.27Å; L264-I300 WeakPolarHBondContact CA-O 3.44Å; L264-I300 HydrophobicContact CD2-CB 4.15Å; L264-I300 HydrophobicContact CD2-CD1 4.49Å; L264-I300 HydrophobicContact CD2-CG2 4.49Å; L264-I300 HydrophobicContact CG-CB 4.09Å; L264-T302 HydrophobicContact CD2-CG2 4.37Å; L264-T331 HydrophobicContact CD2-CG2 4.23Å
265Y95.9Very high96.6Very high0 Ų023.7 Ų23.70%011%0.11CC..EExtended strand (participates in β ladder)trans-142163.8177.843.1-128000112.8I106 F219 P222 Y224 V263 M274 Y299 I300 L301 T302I106-Y265 WeakPolarHBondContact CD1-O 3.5Å; F219-Y265 HydrophobicContact CD2-CD1 4.46Å; F219-Y265 AromaticContact CE2-CD1 3.77Å; F219-Y265 HydrophobicContact CE2-CD1 3.77Å; F219-Y265 HydrophobicContact CZ-CD1 4.01Å; F219-Y265 WeakPolarHBondContact O-CA 3.32Å; F219-Y265 WeakPolarHBondContact O-CB 3.48Å; P222-Y265 HydrophobicContact CB-CD1 4.12Å; P222-Y265 HydrophobicContact CB-CD2 3.37Å; P222-Y265 HydrophobicContact CB-CE1 4.07Å; P222-Y265 HydrophobicContact CB-CE2 3.35Å; P222-Y265 HydrophobicContact CB-CG 3.78Å; Y224-Y265 PolarHBondContact O-OH 2.92Å; V263-Y265 HydrophobicContact CG1-CD1 4.17Å; V263-Y265 HydrophobicContact CG1-CE1 4.47Å; Y265-M274 HydrophobicContact CE2-CE 4.11Å; Y265-M274 WeakPolarHBondContact OH-CE 3.26Å; Y265-Y299 HydrophobicContact CD1-CD1 4.43Å; Y265-Y299 AromaticContact CE1-CD1 3.54Å; Y265-Y299 HydrophobicContact CE1-CD1 3.54Å; Y265-Y299 HydrophobicContact CE1-CE1 4.3Å; Y265-Y299 HydrophobicContact CE1-CG 4.45Å; Y265-I300 PolarHBondContact N-O 3.03Å; Y265-L301 HydrophobicContact CD2-CB 3.93Å; Y265-L301 HydrophobicContact CD2-CD1 3.99Å; Y265-L301 HydrophobicContact CD2-CG 3.93Å; Y265-L301 HydrophobicContact CE2-CB 3.62Å; Y265-L301 HydrophobicContact CE2-CD1 3.76Å; Y265-L301 HydrophobicContact CE2-CG 3.93Å; Y265-L301 CarbonylContact O-C 3.31Å; Y265-L301 WeakPolarHBondContact O-CA 3.33Å; Y265-T302 PolarHBondContact O-N 2.95Å
266G95.5Very high96.6Very high0 Ų023.8 Ų23.80%011%0.111CC..  trans-111.1-129-177.600000111.3D78 H220 K268D78-G266 VanDerWaalsContact OD2-CA 3.3Å; D78-G266 WeakPolarHBondContact OD2-CA 3.46Å; H220-G266 CarbonylContact O-C 3.54Å; H220-G266 VanDerWaalsContact O-C 3.31Å; H220-G266 PolarHBondContact O-N 3.06Å; G266-K268 PolarHBondContact O-N 3.29Å
267H95Very high96.5Very high26 Ų2621.1 Ų21.112%0.1210%0.099CC..SBendtrans68.9-48.3170.8-167.647.3000115.3D78 N143 H220 R221 G232 D238 H269D78-H267 WeakPolarHBondContact OD1-CA 3.38Å; D78-H267 PolarHBondContact OD1-N 3.26Å; D78-H267 PolarHBondContact OD2-N 2.68Å; N143-H267 PolarHBondContact OD1-CE1 3.18Å; N143-H267 PolarHBondContact OD1-ND1 3.22Å; H220-H267 AromaticContact CD2-CG 3.92Å; H220-H267 AromaticContact CD2-ND1 3.81Å; H220-H267 VanDerWaalsContact CE1-CA 3.46Å; H220-H267 WeakPolarHBondContact CE1-CA 3.46Å; H220-H267 PolarHBondContact CE1-N 3.11Å; H220-H267 VanDerWaalsContact CE1-N 3.32Å; H220-H267 WeakPolarHBondContact NE2-CA 3.3Å; H220-H267 VanDerWaalsContact NE2-CB 3.32Å; H220-H267 WeakPolarHBondContact NE2-CB 3.45Å; H220-H267 AromaticContact NE2-CG 3.54Å; H220-H267 AromaticContact NE2-ND1 3.18Å; H220-H267 PolarHBondContact NE2-ND1 3.3Å; H220-H267 VanDerWaalsContact NE2-ND1 3.18Å; H220-H267 WeakPolarHBondContact O-CB 3.41Å; R221-H267 PolarHBondContact NH1-NE2 3.1Å; R221-H267 VanDerWaalsContact NH1-NE2 3.13Å; G232-H267 WeakPolarHBondContact CA-CD2 3.23Å; G232-H267 WeakPolarHBondContact CA-NE2 2.85Å; G232-H267 PolarHBondContact O-CD2 3.1Å; D238-H267 IonicContact OD1-NE2 2.61Å; H267-H269 PolarHBondContact O-CD2 3.34Å; H267-H269 PolarHBondContact O-NE2 3.36Å
268K91.9Very high96.5Very high7 Ų719.5 Ų19.53%0.039%0.087CC..SBendtrans-82.7133168.1-66.5-53.5-134.8165.40110P222 T227 D229 G231 G232 C233 G266 T270 L301 G303 E311P222-K268 HydrophobicContact CG-CG 4.12Å; T227-K268 HydrophobicContact CG2-CG 4.37Å; T227-K268 VanDerWaalsContact OG1-CE 3.23Å; T227-K268 WeakPolarHBondContact OG1-CE 3.44Å; D229-K268 IonicContact OD2-NZ 2.88Å; G231-K268 WeakPolarHBondContact O-CE 3.33Å; G231-K268 PolarHBondContact O-NZ 3.25Å; G232-K268 WeakPolarHBondContact O-CG 3.16Å; C233-K268 HydrophobicContact CB-CD 4.39Å; C233-K268 HydrophobicContact CB-CG 3.95Å; G266-K268 PolarHBondContact O-N 3.29Å; K268-T270 HydrophobicContact CB-CG2 4.42Å; K268-T270 PolarHBondContact O-N 3.31Å; K268-L301 HydrophobicContact CB-CD1 3.8Å; K268-L301 HydrophobicContact CB-CD2 3.99Å; K268-L301 HydrophobicContact CB-CG 4.44Å; K268-L301 HydrophobicContact CG-CD1 4.26Å; K268-L301 WeakPolarHBondContact O-CD2 3.4Å; K268-G303 CarbonylContact O-C 3.4Å; K268-G303 WeakPolarHBondContact O-CA 3.29Å; K268-E311 WeakPolarHBondContact CD-OE2 3.03Å; K268-E311 IonicContact NZ-OE1 3.79Å; K268-E311 PolarHBondContact NZ-OE1 2.92Å; K268-E311 VanDerWaalsContact NZ-OE1 3.15Å; K268-E311 IonicContact NZ-OE2 3.12Å
269H92.6Very high96.4Very high18 Ų1819.9 Ų19.98%0.0839%0.091CC..SBendtrans-82.147-170.2-53.1140.3000113.7D78 Y111 H267 G303 C307 T309 E311D78-H269 IonicContact OD1-CD2 2.71Å; D78-H269 PolarHBondContact OD1-CD2 2.82Å; D78-H269 IonicContact OD1-NE2 3.49Å; D78-H269 PolarHBondContact OD1-NE2 3.04Å; Y111-H269 AromaticContact CE1-NE2 3.98Å; Y111-H269 PolarHBondContact OH-NE2 3.01Å; H267-H269 PolarHBondContact O-CD2 3.34Å; H267-H269 PolarHBondContact O-NE2 3.36Å; H269-G303 VanDerWaalsContact CA-O 3.26Å; H269-G303 WeakPolarHBondContact CA-O 3.47Å; H269-C307 HydrophobicContact CB-CB 4.29Å; H269-C307 PolarHBondContact CE1-SG 3.34Å; H269-C307 PolarHBondContact ND1-SG 3.05Å; H269-C307 VanDerWaalsContact ND1-SG 3.35Å; H269-C307 PolarHBondContact NE2-SG 3.02Å; H269-T309 PolarHBondContact CE1-OG1 2.75Å; H269-T309 PolarHBondContact ND1-OG1 3.22Å; H269-E311 HydrophobicContact CB-CB 4.22Å; H269-E311 HydrophobicContact CB-CG 4.15Å; H269-E311 PolarHBondContact O-N 2.65Å; H269-E311 VanDerWaalsContact O-N 3.11Å
270T91.2Very high96.1Very high6 Ų613.4 Ų13.44%0.0377%0.073CC..SBendtrans-143.4-176.9-172.8-157.20000111.4K268 L301 G303 S304 E311 L325K268-T270 HydrophobicContact CB-CG2 4.42Å; K268-T270 PolarHBondContact O-N 3.31Å; T270-L301 HydrophobicContact CG2-CD2 3.47Å; T270-L301 VanDerWaalsContact CG2-CD2 3.47Å; T270-L301 WeakPolarHBondContact O-CD2 3.47Å; T270-G303 PolarHBondContact O-N 2.94Å; T270-S304 WeakPolarHBondContact O-CB 3.47Å; T270-S304 PolarHBondContact O-OG 2.85Å; T270-S304 VanDerWaalsContact O-OG 3.05Å; T270-E311 WeakPolarHBondContact CB-O 3Å; T270-E311 PolarHBondContact OG1-O 2.83Å; T270-L325 PolarHBondContact OG1-O 3.48Å
271Y94.4Very high95.9Very high0 Ų017.3 Ų17.30%010%0.097CC..EExtended strand (participates in β ladder)trans-123131.4167.6174.8-90.4000110R273 I300 L301 R324 L325 F345 D357Y271-R273 HydrophobicContact CE1-CB 4.26Å; Y271-I300 HydrophobicContact CD2-CG2 4.23Å; Y271-I300 HydrophobicContact CE2-CG2 3.5Å; Y271-L301 WeakPolarHBondContact CA-O 3.43Å; Y271-L301 VanDerWaalsContact CD2-O 3.31Å; Y271-L301 WeakPolarHBondContact CD2-O 3.44Å; Y271-R324 VanDerWaalsContact O-CA 3.28Å; Y271-R324 WeakPolarHBondContact O-CA 3.5Å; Y271-L325 HydrophobicContact CD1-CB 3.92Å; Y271-L325 HydrophobicContact CD1-CD1 3.71Å; Y271-L325 HydrophobicContact CD1-CG 3.77Å; Y271-L325 HydrophobicContact CE1-CD1 4.02Å; Y271-L325 HydrophobicContact CE1-CG 4.34Å; Y271-L325 HydrophobicContact CG-CB 4.39Å; Y271-L325 HydrophobicContact CG-CD1 4.44Å; Y271-L325 PolarHBondContact N-O 3.5Å; Y271-L325 PolarHBondContact O-N 2.91Å; Y271-F345 HydrophobicContact CD1-CD2 4.39Å; Y271-F345 HydrophobicContact CD1-CG 4.43Å; Y271-F345 HydrophobicContact CD2-CB 4.28Å; Y271-F345 AromaticContact CD2-CD2 3.2Å; Y271-F345 HydrophobicContact CD2-CD2 3.2Å; Y271-F345 AromaticContact CD2-CE2 3.7Å; Y271-F345 HydrophobicContact CD2-CE2 3.7Å; Y271-F345 AromaticContact CD2-CG 3.96Å; Y271-F345 HydrophobicContact CD2-CG 3.96Å; Y271-F345 HydrophobicContact CE1-CB 4.3Å; Y271-F345 HydrophobicContact CE2-CB 4Å; Y271-F345 AromaticContact CE2-CD2 3.66Å; Y271-F345 HydrophobicContact CE2-CD2 3.66Å; Y271-F345 HydrophobicContact CE2-CG 4.18Å; Y271-F345 AromaticContact CG-CD2 3.61Å; Y271-F345 HydrophobicContact CG-CD2 3.61Å; Y271-F345 AromaticContact CG-CE2 3.91Å; Y271-F345 HydrophobicContact CG-CE2 3.91Å; Y271-F345 HydrophobicContact CG-CG 4.07Å; Y271-D357 HydrophobicContact CE1-CB 3.95Å; Y271-D357 VanDerWaalsContact CE1-OD2 3.24Å; Y271-D357 WeakPolarHBondContact CE1-OD2 3.36Å; Y271-D357 PolarHBondContact OH-OD2 3.36Å
272E95.6Very high95.7Very high3 Ų317.6 Ų17.61%0.01411%0.105CC..EExtended strand (participates in β ladder)trans-147124.1174.1179.5163.8-158.600110.5C225 S226 M274 I300 L301 S321 T323 R324C225-E272 WeakPolarHBondContact CA-OE2 3.36Å; S226-E272 WeakPolarHBondContact CB-OE1 3.31Å; S226-E272 PolarHBondContact N-OE2 3.36Å; S226-E272 PolarHBondContact OG-OE1 3.48Å; E272-M274 HydrophobicContact CB-CE 4.21Å; E272-M274 HydrophobicContact CG-CE 3.76Å; E272-M274 HydrophobicContact CG-SD 4.19Å; E272-I300 CarbonylContact O-C 3.51Å; E272-I300 WeakPolarHBondContact O-CA 3.32Å; E272-L301 HydrophobicContact CB-CB 4.04Å; E272-L301 PolarHBondContact N-O 3.34Å; E272-L301 PolarHBondContact O-N 3.29Å; E272-S321 WeakPolarHBondContact OE1-CB 3.34Å; E272-S321 PolarHBondContact OE1-OG 3.11Å; E272-T323 CarbonylContact C-O 3.42Å; E272-T323 WeakPolarHBondContact CA-O 3.27Å; E272-R324 HydrophobicContact CB-CG 3.99Å; E272-R324 HydrophobicContact CG-CG 3.65Å; E272-R324 WeakPolarHBondContact OE1-CD 3.49Å
273R96.9Very high95.6Very high2 Ų221.1 Ų21.11%0.00812%0.119CC..EExtended strand (participates in β ladder)trans-102.3131.2168.4-178.6171.359.478.4-1.3109.4Y271 S288 V298 I300 A322 T323 D357Y271-R273 HydrophobicContact CE1-CB 4.26Å; R273-S288 VanDerWaalsContact CZ-O 3.27Å; R273-S288 PolarHBondContact NH1-O 3.38Å; R273-S288 PolarHBondContact NH2-O 3.33Å; R273-S288 VanDerWaalsContact NH2-O 3.14Å; R273-V298 HydrophobicContact CG-CG1 4.41Å; R273-I300 HydrophobicContact CB-CG1 4.44Å; R273-I300 HydrophobicContact CG-CG1 4.07Å; R273-A322 WeakPolarHBondContact O-CA 3.24Å; R273-A322 WeakPolarHBondContact O-CB 3.2Å; R273-A322 PolarHBondContact O-N 3.33Å; R273-T323 PolarHBondContact N-O 3.09Å; R273-T323 PolarHBondContact NH2-OG1 3.44Å; R273-T323 PolarHBondContact O-N 3.3Å; R273-T323 VanDerWaalsContact O-N 3.07Å; R273-D357 WeakPolarHBondContact CB-OD2 3.38Å; R273-D357 IonicContact CZ-OD1 3.88Å; R273-D357 IonicContact CZ-OD2 2.83Å; R273-D357 IonicContact NE-OD1 2.69Å; R273-D357 PolarHBondContact NE-OD1 3.41Å; R273-D357 IonicContact NE-OD2 3.49Å; R273-D357 PolarHBondContact NE-OD2 3.06Å; R273-D357 IonicContact NH2-OD1 2.86Å; R273-D357 PolarHBondContact NH2-OD1 3.1Å; R273-D357 IonicContact NH2-OD2 3.82Å
274M96.3Very high95.4Very high1 Ų127.2 Ų27.21%0.00515%0.145CC..EExtended strand (participates in β ladder)trans-97.9156.9178.3-58.978.8175.100110.6Y224 Y265 E272 I277 Y299 L301 F320Y224-M274 WeakPolarHBondContact O-CE 3.14Å; Y265-M274 HydrophobicContact CE2-CE 4.11Å; Y265-M274 WeakPolarHBondContact OH-CE 3.26Å; E272-M274 HydrophobicContact CB-CE 4.21Å; E272-M274 HydrophobicContact CG-CE 3.76Å; E272-M274 HydrophobicContact CG-SD 4.19Å; M274-I277 HydrophobicContact CB-CG2 4.47Å; M274-Y299 PolarHBondContact N-O 2.82Å; M274-L301 HydrophobicContact CE-CB 4.37Å; M274-F320 WeakPolarHBondContact CA-O 3.08Å; M274-F320 HydrophobicContact CB-CD2 4.47Å; M274-F320 HydrophobicContact CG-CD2 3.8Å; M274-F320 HydrophobicContact CG-CE2 4.27Å
275W97.3Very high95.1Very high25 Ų2529.6 Ų29.610%0.09516%0.162CC..PPolyproline II helixtrans-58.6157.6157.9-67100.6000109.9I277 K284 S285 I291 F320 S321 A322W275-I277 PolarHBondContact O-N 2.81Å; W275-I277 VanDerWaalsContact O-N 3.14Å; W275-K284 HydrophobicContact CD2-CB 4.14Å; W275-K284 HydrophobicContact CD2-CG 3.93Å; W275-K284 HydrophobicContact CE3-CB 4.34Å; W275-K284 HydrophobicContact CG-CG 3.89Å; W275-K284 HydrophobicContact CZ2-CB 4.5Å; W275-S285 VanDerWaalsContact CH2-O 3.31Å; W275-S285 WeakPolarHBondContact CH2-O 3.44Å; W275-S285 VanDerWaalsContact CZ3-N 3.28Å; W275-S285 VanDerWaalsContact CZ3-OG 3.31Å; W275-S285 WeakPolarHBondContact CZ3-OG 3.46Å; W275-I291 HydrophobicContact CE3-CD1 3.61Å; W275-I291 HydrophobicContact CZ3-CD1 3.6Å; W275-F320 PolarHBondContact N-O 3.11Å; W275-S321 PolarHBondContact NE1-O 3.35Å; W275-A322 HydrophobicContact CD2-CB 4.19Å; W275-A322 HydrophobicContact CG-CB 4.22Å
276P98.1Very high95Very high2 Ų236 Ų361%0.01321%0.207CC..SBendtrans-46.8127164.4-24.130.8000109.6G282 Y283 I291 A294 A296 P297 V298P276-G282 CarbonylContact O-C 3.54Å; P276-G282 WeakPolarHBondContact O-CA 3.46Å; P276-Y283 HydrophobicContact CB-CD2 4.42Å; P276-Y283 WeakPolarHBondContact O-CD2 3.33Å; P276-Y283 PolarHBondContact O-N 3.31Å; P276-I291 HydrophobicContact CG-CD1 3.95Å; P276-I291 HydrophobicContact CG-CG1 4.42Å; P276-I291 HydrophobicContact CG-CG2 3.88Å; P276-A294 HydrophobicContact CB-CB 4.27Å; P276-A294 HydrophobicContact CG-CB 3.93Å; P276-A296 HydrophobicContact CB-CB 4.25Å; P276-A296 WeakPolarHBondContact CB-O 3.36Å; P276-P297 WeakPolarHBondContact CA-O 3.39Å; P276-V298 HydrophobicContact CB-CG2 4.5Å; P276-V298 HydrophobicContact CG-CG2 3.88Å
277I97.6Very high94.9Very high0 Ų039.8 Ų39.80%023%0.227CC..EExtended strand (participates in β ladder)trans-140.7140.3-173.3178.1158.7000110.9Y224 M274 W275 T281 P297 Y299 F320Y224-I277 HydrophobicContact CD1-CD1 3.65Å; Y224-I277 HydrophobicContact CD1-CG1 4.48Å; Y224-I277 HydrophobicContact CD2-CD1 4.43Å; Y224-I277 HydrophobicContact CD2-CG2 3.83Å; Y224-I277 HydrophobicContact CE1-CD1 3.37Å; Y224-I277 HydrophobicContact CE1-CG1 3.92Å; Y224-I277 HydrophobicContact CE2-CD1 4.22Å; Y224-I277 HydrophobicContact CE2-CG1 4.03Å; Y224-I277 HydrophobicContact CE2-CG2 3.81Å; Y224-I277 HydrophobicContact CG-CD1 4.18Å; Y224-I277 HydrophobicContact CG-CG2 4.41Å; M274-I277 HydrophobicContact CB-CG2 4.47Å; W275-I277 PolarHBondContact O-N 2.81Å; W275-I277 VanDerWaalsContact O-N 3.14Å; I277-T281 WeakPolarHBondContact CA-O 3.39Å; I277-P297 PolarHBondContact N-O 3.31Å; I277-Y299 HydrophobicContact CG2-CD2 3.34Å; I277-Y299 HydrophobicContact CG2-CE2 3.61Å; I277-Y299 HydrophobicContact CG2-CG 4.23Å; I277-Y299 WeakPolarHBondContact O-CE2 3.48Å; I277-F320 HydrophobicContact CD1-CB 3.45Å; I277-F320 VanDerWaalsContact CD1-CB 3.45Å; I277-F320 HydrophobicContact CD1-CD1 3.83Å; I277-F320 HydrophobicContact CD1-CG 3.73Å
278Y97.8Very high94.9Very high52 Ų5240.5 Ų40.520%0.20424%0.235CC..EExtended strand (participates in β ladder)trans-143.2132.4170.5174.3-109.8000109.4E252 F256 G280 T281E252-Y278 HydrophobicContact CG-CD2 4.03Å; E252-Y278 HydrophobicContact CG-CE2 4.18Å; F256-Y278 HydrophobicContact CB-CD2 3.54Å; F256-Y278 HydrophobicContact CB-CE2 3.56Å; F256-Y278 HydrophobicContact CB-CG 4.39Å; F256-Y278 HydrophobicContact CD1-CD1 4.42Å; F256-Y278 HydrophobicContact CD1-CD2 4.14Å; F256-Y278 HydrophobicContact CD1-CE1 4.24Å; F256-Y278 AromaticContact CD1-CE2 3.94Å; F256-Y278 HydrophobicContact CD1-CE2 3.94Å; F256-Y278 HydrophobicContact CD1-CG 4.36Å; F256-Y278 AromaticContact CD1-CZ 3.99Å; F256-Y278 HydrophobicContact CD2-CD1 4.17Å; F256-Y278 AromaticContact CD2-CD2 3.55Å; F256-Y278 HydrophobicContact CD2-CD2 3.55Å; F256-Y278 HydrophobicContact CD2-CE2 4.19Å; F256-Y278 AromaticContact CD2-CG 3.52Å; F256-Y278 HydrophobicContact CD2-CG 3.52Å; F256-Y278 HydrophobicContact CE1-CD1 4.34Å; F256-Y278 HydrophobicContact CE1-CE1 4.27Å; F256-Y278 HydrophobicContact CE2-CD1 4.07Å; F256-Y278 HydrophobicContact CE2-CD2 4.27Å; F256-Y278 AromaticContact CE2-CG 3.79Å; F256-Y278 HydrophobicContact CE2-CG 3.79Å; F256-Y278 HydrophobicContact CG-CD1 4.33Å; F256-Y278 AromaticContact CG-CD2 3.46Å; F256-Y278 HydrophobicContact CG-CD2 3.46Å; F256-Y278 VanDerWaalsContact CG-CD2 3.46Å; F256-Y278 HydrophobicContact CG-CE1 4.48Å; F256-Y278 AromaticContact CG-CE2 3.63Å; F256-Y278 HydrophobicContact CG-CE2 3.63Å; F256-Y278 AromaticContact CG-CG 3.83Å; F256-Y278 HydrophobicContact CG-CG 3.83Å; F256-Y278 HydrophobicContact CZ-CD1 4.16Å; F256-Y278 HydrophobicContact CZ-CG 4.32Å; Y278-G280 VanDerWaalsContact C-N 3.28Å; Y278-G280 PolarHBondContact O-N 2.74Å; Y278-T281 PolarHBondContact N-O 3.34Å; Y278-T281 WeakPolarHBondContact O-CB 3.45Å; Y278-T281 PolarHBondContact O-N 3.49Å
279D95.7Very high95.1Very high76 Ų7641 Ų4141%0.40624%0.241SC..THydrogen-bonded Turntrans49.847.2177.4-16623.7000113.1Y224 K243 E252 T281Y224-D279 PolarHBondContact OH-N 2.81Å; K243-D279 WeakPolarHBondContact CE-OD1 3.29Å; K243-D279 IonicContact NZ-OD1 3.86Å; K243-D279 PolarHBondContact NZ-OD1 3.48Å; E252-D279 PolarHBondContact OE1-N 2.94Å; E252-D279 VanDerWaalsContact OE1-N 3.09Å; D279-T281 PolarHBondContact O-N 3.11Å
280G93.1Very high95.3Very high37 Ų3743.5 Ų43.538%0.38125%0.253SS..THydrogen-bonded Turntrans74.9-2.8-179.500000115.5Y224 Y278Y224-G280 PolarHBondContact OH-N 3.45Å; Y278-G280 VanDerWaalsContact C-N 3.28Å; Y278-G280 PolarHBondContact O-N 2.74Å
281T94.1Very high95.6Very high85 Ų8543.5 Ų43.552%0.52125%0.253SS..EExtended strand (participates in β ladder)trans-102.4109.6-178-56.90000111I277 Y278 D279I277-T281 WeakPolarHBondContact CA-O 3.39Å; Y278-T281 PolarHBondContact N-O 3.34Å; Y278-T281 WeakPolarHBondContact O-CB 3.45Å; Y278-T281 PolarHBondContact O-N 3.49Å; D279-T281 PolarHBondContact O-N 3.11Å
282G95.3Very high95.8Very high26 Ų2650.4 Ų50.427%0.26828%0.279SS..EExtended strand (participates in β ladder)trans-81130.8176.100000113.1P276 K284P276-G282 CarbonylContact O-C 3.54Å; P276-G282 WeakPolarHBondContact O-CA 3.46Å; G282-K284 PolarHBondContact O-N 3.15Å
283Y96.1Very high95.8Very high76 Ų7653.5 Ų53.530%0.29830%0.296SS..  trans-94.989.5174.3-55.7-88.9000110.1P276 K295 A296P276-Y283 HydrophobicContact CB-CD2 4.42Å; P276-Y283 WeakPolarHBondContact O-CD2 3.33Å; P276-Y283 PolarHBondContact O-N 3.31Å; Y283-K295 HydrophobicContact CD1-CB 3.98Å; Y283-K295 HydrophobicContact CD1-CD 3.8Å; Y283-K295 HydrophobicContact CD1-CG 4.47Å; Y283-K295 HydrophobicContact CD2-CB 4.27Å; Y283-K295 HydrophobicContact CE1-CB 4.2Å; Y283-K295 HydrophobicContact CE1-CD 4.18Å; Y283-K295 HydrophobicContact CE2-CB 4.5Å; Y283-K295 HydrophobicContact CG-CB 4.01Å; Y283-K295 HydrophobicContact CG-CD 4.47Å; Y283-A296 HydrophobicContact CD2-CB 3.81Å; Y283-A296 HydrophobicContact CE2-CB 3.68Å
284K95.2Very high95.8Very high128 Ų12855.2 Ų55.256%0.55731%0.31SS*.  trans-75.7143.1179.6-56.2-171.7179.4-1720111.8W275 G282 S319W275-K284 HydrophobicContact CD2-CB 4.14Å; W275-K284 HydrophobicContact CD2-CG 3.93Å; W275-K284 HydrophobicContact CE3-CB 4.34Å; W275-K284 HydrophobicContact CG-CG 3.89Å; W275-K284 HydrophobicContact CZ2-CB 4.5Å; G282-K284 PolarHBondContact O-N 3.15Å; K284-S319 WeakPolarHBondContact CE-O 3.47Å; K284-S319 PolarHBondContact NZ-O 3.18Å
285S92.1Very high95.8Very high51 Ų5162.6 Ų62.636%0.35734%0.342SS..  trans-110.9177.8164.770.70000109.9W275 D287W275-S285 VanDerWaalsContact CH2-O 3.31Å; W275-S285 WeakPolarHBondContact CH2-O 3.44Å; W275-S285 VanDerWaalsContact CZ3-N 3.28Å; W275-S285 VanDerWaalsContact CZ3-OG 3.31Å; W275-S285 WeakPolarHBondContact CZ3-OG 3.46Å; S285-D287 VanDerWaalsContact C-N 3.28Å; S285-D287 PolarHBondContact OG-N 2.76Å; S285-D287 PolarHBondContact OG-O 2.86Å
286S92.4Very high95.9Very high135 Ų13561.8 Ų61.894%0.94434%0.341SS*.SBendtrans-70.4-23.7176.652.10000113.7
287D94.9Very high95.9Very high80 Ų8061.8 Ų61.843%0.42834%0.341SS..  trans-125.9112.7-177.7-176.40.8000109.6S285 G289 H290S285-D287 VanDerWaalsContact C-N 3.28Å; S285-D287 PolarHBondContact OG-N 2.76Å; S285-D287 PolarHBondContact OG-O 2.86Å; D287-G289 PolarHBondContact O-N 2.97Å; D287-G289 WeakPolarHBondContact OD1-CA 3.44Å; D287-G289 PolarHBondContact OD1-N 2.66Å; D287-H290 CarbonylContact O-C 3.47Å; D287-H290 PolarHBondContact O-N 2.9Å
288S93.4Very high95.9Very high41 Ų4161.8 Ų61.829%0.28734%0.341SS..THydrogen-bonded Turntrans-72.6-19.9176.862.70000112.6R273R273-S288 VanDerWaalsContact CZ-O 3.27Å; R273-S288 PolarHBondContact NH1-O 3.38Å; R273-S288 PolarHBondContact NH2-O 3.33Å; R273-S288 VanDerWaalsContact NH2-O 3.14Å
289G96.9Very high95.9Very high16 Ų1659.4 Ų59.417%0.16533%0.332CS..THydrogen-bonded Turntrans-82-12.8177.200000113.7D287 F359 Y360D287-G289 PolarHBondContact O-N 2.97Å; D287-G289 WeakPolarHBondContact OD1-CA 3.44Å; D287-G289 PolarHBondContact OD1-N 2.66Å; G289-F359 CarbonylContact O-C 3.58Å; G289-F359 WeakPolarHBondContact O-CA 3.29Å; G289-Y360 PolarHBondContact O-N 2.93Å
290H97.6Very high96Very high71 Ų7155.8 Ų55.833%0.32931%0.312SS..EExtended strand (participates in β ladder)trans-144.6108-179.9-171.4-177.3000111.2D287 Y360 E362D287-H290 CarbonylContact O-C 3.47Å; D287-H290 PolarHBondContact O-N 2.9Å; H290-Y360 WeakPolarHBondContact CA-O 3.46Å; H290-E362 IonicContact CE1-OE2 3.43Å; H290-E362 PolarHBondContact CE1-OE2 3.29Å; H290-E362 IonicContact NE2-OE2 3.15Å; H290-E362 PolarHBondContact NE2-OE2 2.99Å
291I97.6Very high96.2Very high7 Ų754 Ų544%0.03629%0.294CS..EExtended strand (participates in β ladder)trans-102.1122.5174.7-62.6-81.3000108.5W275 P276 A294 F359 Y360 L361 E362W275-I291 HydrophobicContact CE3-CD1 3.61Å; W275-I291 HydrophobicContact CZ3-CD1 3.6Å; P276-I291 HydrophobicContact CG-CD1 3.95Å; P276-I291 HydrophobicContact CG-CG1 4.42Å; P276-I291 HydrophobicContact CG-CG2 3.88Å; I291-A294 HydrophobicContact CG2-CB 3.65Å; I291-F359 HydrophobicContact CB-CE2 3.92Å; I291-F359 HydrophobicContact CB-CZ 4.14Å; I291-F359 HydrophobicContact CG1-CE2 3.54Å; I291-F359 HydrophobicContact CG1-CZ 4.02Å; I291-Y360 PolarHBondContact N-O 2.71Å; I291-L361 HydrophobicContact CB-CD1 4Å; I291-L361 HydrophobicContact CG2-CD1 3.81Å; I291-L361 WeakPolarHBondContact O-CA 3.42Å; I291-E362 PolarHBondContact O-N 2.95Å
292R97.1Very high96.3Very high144 Ų14450 Ų5054%0.54327%0.269SS..EExtended strand (participates in β ladder)trans-107.2133.9171.6-176.4172.9178.6164.53.3110.8A294 E362 D364R292-A294 PolarHBondContact O-N 3.41Å; R292-E362 CarbonylContact C-O 3.52Å; R292-E362 WeakPolarHBondContact CA-O 3.31Å; R292-E362 HydrophobicContact CB-CB 4.35Å; R292-E362 WeakPolarHBondContact CD-OE1 3.37Å; R292-E362 HydrophobicContact CG-CB 4.3Å; R292-E362 HydrophobicContact CG-CG 4.14Å; R292-E362 IonicContact CZ-OE1 3.69Å; R292-E362 VanDerWaalsContact CZ-OE1 3.24Å; R292-E362 IonicContact NE-OE1 3.22Å; R292-E362 PolarHBondContact NE-OE1 3.07Å; R292-E362 IonicContact NH1-OE1 3.85Å; R292-E362 PolarHBondContact NH1-OE1 2.79Å; R292-E362 IonicContact NH2-OE1 3.25Å; R292-D364 IonicContact CZ-OD1 3.74Å; R292-D364 IonicContact NE-OD1 3.8Å; R292-D364 PolarHBondContact NE-OD1 2.84Å; R292-D364 IonicContact NH2-OD1 3.24Å; R292-D364 PolarHBondContact NH2-OD1 2.8Å; R292-D364 IonicContact NH2-OD2 2.76Å
293N95.9Very high96.2Very high69 Ų6948.7 Ų48.737%0.36926%0.256SS..SBendtrans48.758179-64.1-40.4000112.1K295 E362 K363 D364N293-K295 PolarHBondContact O-N 3.07Å; N293-E362 PolarHBondContact N-O 3.35Å; N293-K363 WeakPolarHBondContact OD1-CA 3.48Å; N293-D364 VanDerWaalsContact ND2-CG 3.34Å; N293-D364 PolarHBondContact ND2-OD2 3.35Å; N293-D364 PolarHBondContact OD1-N 2.68Å
294A97Very high96.1Very high37 Ų3745.1 Ų45.131%0.30624%0.242SC..  trans-51.8131.8179.600000111P276 I291 R292 A296 L361P276-A294 HydrophobicContact CB-CB 4.27Å; P276-A294 HydrophobicContact CG-CB 3.93Å; I291-A294 HydrophobicContact CG2-CB 3.65Å; R292-A294 PolarHBondContact O-N 3.41Å; A294-A296 VanDerWaalsContact C-N 3.28Å; A294-A296 WeakPolarHBondContact CB-O 3.3Å; A294-A296 PolarHBondContact O-N 3.31Å; A294-L361 HydrophobicContact CB-CD1 3.88Å
295K96.9Very high96.1Very high156 Ų15639 Ų3968%0.67822%0.216SC*.SBendtrans-80.2-11.5-179.5-64.3-176.5-179.51790113.4F256 Y283 N293F256-K295 VanDerWaalsContact CE2-O 3.26Å; F256-K295 WeakPolarHBondContact CE2-O 3.26Å; Y283-K295 HydrophobicContact CD1-CB 3.98Å; Y283-K295 HydrophobicContact CD1-CD 3.8Å; Y283-K295 HydrophobicContact CD1-CG 4.47Å; Y283-K295 HydrophobicContact CD2-CB 4.27Å; Y283-K295 HydrophobicContact CE1-CB 4.2Å; Y283-K295 HydrophobicContact CE1-CD 4.18Å; Y283-K295 HydrophobicContact CE2-CB 4.5Å; Y283-K295 HydrophobicContact CG-CB 4.01Å; Y283-K295 HydrophobicContact CG-CD 4.47Å; N293-K295 PolarHBondContact O-N 3.07Å
296A98.1Very high96Very high8 Ų836.6 Ų36.67%0.06620%0.199CC..SBendtrans-151.8167.4-178.900000108.6F256 P276 Y283 A294F256-A296 HydrophobicContact CD2-CB 4.08Å; F256-A296 HydrophobicContact CE2-CB 3.98Å; P276-A296 HydrophobicContact CB-CB 4.25Å; P276-A296 WeakPolarHBondContact CB-O 3.36Å; Y283-A296 HydrophobicContact CD2-CB 3.81Å; Y283-A296 HydrophobicContact CE2-CB 3.68Å; A294-A296 VanDerWaalsContact C-N 3.28Å; A294-A296 WeakPolarHBondContact CB-O 3.3Å; A294-A296 PolarHBondContact O-N 3.31Å
297P98.3Very high95.5Very high2 Ų230.2 Ų30.21%0.01315%0.154CC..PPolyproline II helixtrans-60143.9175-1828.3000111.8V260 V263 P276 I277 Y299V260-P297 HydrophobicContact CB-CG 4.19Å; V260-P297 HydrophobicContact CG1-CB 4.42Å; V260-P297 WeakPolarHBondContact O-CA 3.23Å; V260-P297 WeakPolarHBondContact O-CB 3.11Å; V260-P297 VanDerWaalsContact O-CG 3.28Å; V260-P297 WeakPolarHBondContact O-CG 3.26Å; V263-P297 HydrophobicContact CG2-CB 4.03Å; P276-P297 WeakPolarHBondContact CA-O 3.39Å; I277-P297 PolarHBondContact N-O 3.31Å; P297-Y299 HydrophobicContact CB-CE2 3.92Å; P297-Y299 HydrophobicContact CG-CE2 4.45Å; P297-Y299 WeakPolarHBondContact O-CD2 3.4Å; P297-Y299 WeakPolarHBondContact O-CE2 3.29Å
298V98.2Very high94.4Very high1 Ų131.6 Ų31.61%0.00616%0.158CC..EExtended strand (participates in β ladder)trans-84.5131.4167176.30000108.8D261 M262 V263 R273 P276 F359 L361D261-V298 PolarHBondContact O-N 3.03Å; M262-V298 CarbonylContact C-O 3.49Å; M262-V298 VanDerWaalsContact CA-O 3.26Å; M262-V298 WeakPolarHBondContact CA-O 3.42Å; V263-V298 PolarHBondContact N-O 3.29Å; R273-V298 HydrophobicContact CG-CG1 4.41Å; P276-V298 HydrophobicContact CB-CG2 4.5Å; P276-V298 HydrophobicContact CG-CG2 3.88Å; V298-F359 HydrophobicContact CB-CZ 4.5Å; V298-F359 HydrophobicContact CG1-CE1 3.93Å; V298-F359 HydrophobicContact CG1-CZ 4.05Å; V298-F359 HydrophobicContact CG2-CE1 4.49Å; V298-F359 HydrophobicContact CG2-CZ 4.02Å; V298-L361 HydrophobicContact CG2-CD1 4.29Å
299Y97.8Very high93.2Very high1 Ų132.7 Ų32.70%0.00416%0.163CC..EExtended strand (participates in β ladder)trans-103.7138.4179.3-66.7-104.6000110.6W223 Y224 V263 Y265 M274 I277 P297W223-Y299 AromaticContact CE3-CE1 3.62Å; W223-Y299 HydrophobicContact CE3-CE1 3.62Å; W223-Y299 AromaticContact CZ3-CE1 3.97Å; W223-Y299 HydrophobicContact CZ3-CE1 3.97Å; W223-Y299 WeakPolarHBondContact CZ3-OH 3.43Å; Y224-Y299 HydrophobicContact CD2-CD1 4.32Å; Y224-Y299 HydrophobicContact CD2-CD2 4.49Å; Y224-Y299 HydrophobicContact CD2-CE1 4.34Å; Y224-Y299 HydrophobicContact CD2-CG 4.37Å; Y224-Y299 HydrophobicContact CE2-CE1 4.47Å; Y224-Y299 HydrophobicContact CE2-CE2 4.36Å; V263-Y299 HydrophobicContact CB-CD1 3.47Å; V263-Y299 VanDerWaalsContact CB-CD1 3.47Å; V263-Y299 HydrophobicContact CB-CE1 3.53Å; V263-Y299 HydrophobicContact CB-CG 4.15Å; V263-Y299 HydrophobicContact CG1-CD1 3.63Å; V263-Y299 HydrophobicContact CG1-CE1 3.62Å; V263-Y299 HydrophobicContact CG2-CD1 4.2Å; V263-Y299 HydrophobicContact CG2-CE1 3.75Å; V263-Y299 CarbonylContact O-C 3.55Å; V263-Y299 VanDerWaalsContact O-CA 3.27Å; V263-Y299 WeakPolarHBondContact O-CA 3.21Å; Y265-Y299 HydrophobicContact CD1-CD1 4.43Å; Y265-Y299 AromaticContact CE1-CD1 3.54Å; Y265-Y299 HydrophobicContact CE1-CD1 3.54Å; Y265-Y299 HydrophobicContact CE1-CE1 4.3Å; Y265-Y299 HydrophobicContact CE1-CG 4.45Å; M274-Y299 PolarHBondContact N-O 2.82Å; I277-Y299 HydrophobicContact CG2-CD2 3.34Å; I277-Y299 HydrophobicContact CG2-CE2 3.61Å; I277-Y299 HydrophobicContact CG2-CG 4.23Å; I277-Y299 WeakPolarHBondContact O-CE2 3.48Å; P297-Y299 HydrophobicContact CB-CE2 3.92Å; P297-Y299 HydrophobicContact CG-CE2 4.45Å; P297-Y299 WeakPolarHBondContact O-CD2 3.4Å; P297-Y299 WeakPolarHBondContact O-CE2 3.29Å
300I98.1Very high91.7Very high0 Ų035.7 Ų35.70%017%0.173CC..EExtended strand (participates in β ladder)trans-130.4118.1172.5-56.2-177000109.4M262 V263 L264 Y265 Y271 E272 R273 T343M262-I300 HydrophobicContact CE-CD1 3.36Å; M262-I300 HydrophobicContact CE-CG1 4.06Å; V263-I300 PolarHBondContact O-N 3.45Å; L264-I300 VanDerWaalsContact CA-O 3.27Å; L264-I300 WeakPolarHBondContact CA-O 3.44Å; L264-I300 HydrophobicContact CD2-CB 4.15Å; L264-I300 HydrophobicContact CD2-CD1 4.49Å; L264-I300 HydrophobicContact CD2-CG2 4.49Å; L264-I300 HydrophobicContact CG-CB 4.09Å; Y265-I300 PolarHBondContact N-O 3.03Å; Y271-I300 HydrophobicContact CD2-CG2 4.23Å; Y271-I300 HydrophobicContact CE2-CG2 3.5Å; E272-I300 CarbonylContact O-C 3.51Å; E272-I300 WeakPolarHBondContact O-CA 3.32Å; R273-I300 HydrophobicContact CB-CG1 4.44Å; R273-I300 HydrophobicContact CG-CG1 4.07Å; I300-T343 HydrophobicContact CD1-CG2 4.12Å
301L96.3Very high90.4Very high0 Ų034.7 Ų34.70%017%0.168CC..EExtended strand (participates in β ladder)trans-80.7119.8163-161136.9000109.2P222 C225 Y265 K268 T270 Y271 E272 M274P222-L301 HydrophobicContact CB-CD1 3.72Å; P222-L301 HydrophobicContact CG-CD1 3.92Å; C225-L301 HydrophobicContact CB-CD1 3.91Å; Y265-L301 HydrophobicContact CD2-CB 3.93Å; Y265-L301 HydrophobicContact CD2-CD1 3.99Å; Y265-L301 HydrophobicContact CD2-CG 3.93Å; Y265-L301 HydrophobicContact CE2-CB 3.62Å; Y265-L301 HydrophobicContact CE2-CD1 3.76Å; Y265-L301 HydrophobicContact CE2-CG 3.93Å; Y265-L301 CarbonylContact O-C 3.31Å; Y265-L301 WeakPolarHBondContact O-CA 3.33Å; K268-L301 HydrophobicContact CB-CD1 3.8Å; K268-L301 HydrophobicContact CB-CD2 3.99Å; K268-L301 HydrophobicContact CB-CG 4.44Å; K268-L301 HydrophobicContact CG-CD1 4.26Å; K268-L301 WeakPolarHBondContact O-CD2 3.4Å; T270-L301 HydrophobicContact CG2-CD2 3.47Å; T270-L301 VanDerWaalsContact CG2-CD2 3.47Å; T270-L301 WeakPolarHBondContact O-CD2 3.47Å; Y271-L301 WeakPolarHBondContact CA-O 3.43Å; Y271-L301 VanDerWaalsContact CD2-O 3.31Å; Y271-L301 WeakPolarHBondContact CD2-O 3.44Å; E272-L301 HydrophobicContact CB-CB 4.04Å; E272-L301 PolarHBondContact N-O 3.34Å; E272-L301 PolarHBondContact O-N 3.29Å; M274-L301 HydrophobicContact CE-CB 4.37Å
302T96.2Very high88.9Confident0 Ų035.9 Ų35.90%018%0.182CC..EExtended strand (participates in β ladder)trans-136.539.2-176.6-171.30000112.7I75 G77 I106 L264 Y265 S304 T331I75-T302 HydrophobicContact CG2-CG2 4.44Å; G77-T302 PolarHBondContact N-O 3.25Å; I106-T302 HydrophobicContact CD1-CG2 3.37Å; L264-T302 HydrophobicContact CD2-CG2 4.37Å; Y265-T302 PolarHBondContact O-N 2.95Å; T302-S304 PolarHBondContact O-N 3.38Å; T302-T331 WeakPolarHBondContact CB-OG1 3.41Å; T302-T331 PolarHBondContact OG1-OG1 3.1Å
303G95Very high87.5Confident0 Ų031.4 Ų31.40%017%0.171CC..  trans-84.129.9178.500000114.7D78 K268 H269 T270D78-G303 WeakPolarHBondContact CB-O 3.45Å; D78-G303 WeakPolarHBondContact OD2-CA 3.39Å; K268-G303 CarbonylContact O-C 3.4Å; K268-G303 WeakPolarHBondContact O-CA 3.29Å; H269-G303 VanDerWaalsContact CA-O 3.26Å; H269-G303 WeakPolarHBondContact CA-O 3.47Å; T270-G303 PolarHBondContact O-N 2.94Å
304S93.4Very high86Confident0 Ų033.2 Ų33.20%019%0.189CC..  trans-108.826.5-17338.70000113.2T270 T302 G306 Y328 G329 F345T270-S304 WeakPolarHBondContact O-CB 3.47Å; T270-S304 PolarHBondContact O-OG 2.85Å; T270-S304 VanDerWaalsContact O-OG 3.05Å; T302-S304 PolarHBondContact O-N 3.38Å; S304-G306 VanDerWaalsContact C-N 3.26Å; S304-G306 PolarHBondContact O-N 3.18Å; S304-Y328 CarbonylContact O-C 3.46Å; S304-Y328 WeakPolarHBondContact O-CA 3.12Å; S304-Y328 WeakPolarHBondContact O-CB 3.27Å; S304-Y328 VanDerWaalsContact O-CD1 3.26Å; S304-Y328 WeakPolarHBondContact O-CD1 3.22Å; S304-G329 CarbonylContact C-O 3.58Å; S304-G329 PolarHBondContact O-N 3.33Å; S304-F345 WeakPolarHBondContact OG-CE2 3.47Å
305A94.6Very high84.9Confident1 Ų132.7 Ų32.71%0.00818%0.182CC..SBendtrans-71.1-18.9-175.700000114.3F76 G77 L79 S87 G329F76-A305 HydrophobicContact CB-CB 3.98Å; F76-A305 HydrophobicContact CD2-CB 3.75Å; F76-A305 HydrophobicContact CG-CB 4.15Å; G77-A305 WeakPolarHBondContact O-CB 3.4Å; G77-A305 PolarHBondContact O-N 3.4Å; L79-A305 HydrophobicContact CB-CB 3.87Å; L79-A305 HydrophobicContact CD1-CB 3.82Å; L79-A305 WeakPolarHBondContact CD1-O 3.41Å; L79-A305 HydrophobicContact CG-CB 4.39Å; S87-A305 WeakPolarHBondContact CB-O 3.12Å; S87-A305 PolarHBondContact OG-O 3.23Å; A305-G329 WeakPolarHBondContact CA-O 3.38Å; A305-G329 PolarHBondContact N-O 2.86Å
306G89.8Confident84.2Confident0 Ų028.7 Ų28.70%018%0.178CC..BIsolated β-bridgetrans136.168.1175.700000112.1D78 S80 G84 S304D78-G306 CarbonylContact O-C 3.41Å; D78-G306 PolarHBondContact O-N 3.13Å; S80-G306 WeakPolarHBondContact CB-O 3.44Å; S80-G306 PolarHBondContact N-O 2.75Å; S80-G306 VanDerWaalsContact N-O 3.11Å; S80-G306 PolarHBondContact OG-O 3.32Å; G84-G306 PolarHBondContact N-O 3.03Å; S304-G306 VanDerWaalsContact C-N 3.26Å; S304-G306 PolarHBondContact O-N 3.18Å
307C82.3Confident83.7Confident0 Ų032.2 Ų32.20%020%0.2CC..  trans-73.6165.1174.7178.80000113D78 K83 Y111 H269 T309 Y328D78-C307 PolarHBondContact O-N 3.07Å; K83-C307 WeakPolarHBondContact CB-O 3.25Å; K83-C307 WeakPolarHBondContact CG-O 3.47Å; Y111-C307 HydrophobicContact CE1-CB 4.29Å; Y111-C307 WeakPolarHBondContact CE1-SG 3.26Å; Y111-C307 HydrophobicContact CE2-CB 3.94Å; Y111-C307 WeakPolarHBondContact OH-CB 3.3Å; Y111-C307 PolarHBondContact OH-SG 3.44Å; H269-C307 HydrophobicContact CB-CB 4.29Å; H269-C307 PolarHBondContact CE1-SG 3.34Å; H269-C307 PolarHBondContact ND1-SG 3.05Å; H269-C307 VanDerWaalsContact ND1-SG 3.35Å; H269-C307 PolarHBondContact NE2-SG 3.02Å; C307-T309 VanDerWaalsContact CB-O 3.28Å; C307-T309 WeakPolarHBondContact CB-O 3.28Å; C307-T309 PolarHBondContact O-N 2.89Å; C307-T309 PolarHBondContact SG-N 2.99Å; C307-Y328 PolarHBondContact O-OH 3.21Å
308H71.2Confident83.3Confident110 Ų11036.8 Ų36.851%0.50922%0.221SC..SBendtrans-60-19164.866.4-85.3000114.1Y111Y111-H308 AromaticContact CD1-CE1 3.39Å; Y111-H308 WeakPolarHBondContact CD1-CE1 3.38Å; Y111-H308 AromaticContact CD1-ND1 3.11Å; Y111-H308 WeakPolarHBondContact CD1-ND1 3.47Å; Y111-H308 AromaticContact CE1-CE1 3.59Å; Y111-H308 AromaticContact CE1-ND1 3.41Å; Y111-H308 WeakPolarHBondContact CE1-ND1 3.12Å; Y111-H308 AromaticContact CG-ND1 3.59Å
309T68.2Low83Confident63 Ų6340.7 Ų40.739%0.38725%0.249SC..SBendtrans-122.5164.217057.80000111.5H269 C307 Y328H269-T309 PolarHBondContact CE1-OG1 2.75Å; H269-T309 PolarHBondContact ND1-OG1 3.22Å; C307-T309 VanDerWaalsContact CB-O 3.28Å; C307-T309 WeakPolarHBondContact CB-O 3.28Å; C307-T309 PolarHBondContact O-N 2.89Å; C307-T309 PolarHBondContact SG-N 2.99Å; T309-Y328 PolarHBondContact O-OH 3.08Å; T309-Y328 VanDerWaalsContact O-OH 3.1Å
310H66.4Low82.7Confident80 Ų8041.7 Ų41.737%0.3725%0.253SS..  trans-130.3119.8176.2-173.767000109.5G326 Y328H310-G326 PolarHBondContact CE1-O 2.86Å; H310-G326 PolarHBondContact NE2-O 3.24Å; H310-Y328 HydrophobicContact CB-CE1 4.1Å; H310-Y328 WeakPolarHBondContact CB-OH 3.16Å; H310-Y328 AromaticContact CG-CE1 3.94Å; H310-Y328 AromaticContact CG-CZ 3.9Å; H310-Y328 AromaticContact ND1-CD1 3.44Å; H310-Y328 WeakPolarHBondContact ND1-CD1 3.19Å; H310-Y328 AromaticContact ND1-CE1 3.12Å; H310-Y328 WeakPolarHBondContact ND1-CE1 3.41Å; H310-Y328 AromaticContact ND1-CZ 3.47Å
311E70.4Confident82.6Confident50 Ų5042.4 Ų42.423%0.23426%0.258CS..  trans-100105174.3-67.3-174.1174.200108.8K268 H269 T270K268-E311 WeakPolarHBondContact CD-OE2 3.03Å; K268-E311 IonicContact NZ-OE1 3.79Å; K268-E311 PolarHBondContact NZ-OE1 2.92Å; K268-E311 VanDerWaalsContact NZ-OE1 3.15Å; K268-E311 IonicContact NZ-OE2 3.12Å; H269-E311 HydrophobicContact CB-CB 4.22Å; H269-E311 HydrophobicContact CB-CG 4.15Å; H269-E311 PolarHBondContact O-N 2.65Å; H269-E311 VanDerWaalsContact O-N 3.11Å; T270-E311 WeakPolarHBondContact CB-O 3Å; T270-E311 PolarHBondContact OG1-O 2.83Å
312G66.1Low82.5Confident32 Ų3243.6 Ų43.633%0.3327%0.268SS..  trans-77.7158.3168.400000110.9S314G312-S314 PolarHBondContact O-N 2.81Å
313P67.4Low82.5Confident49 Ų4945.2 Ų45.232%0.31828%0.278SS..  trans-7663.4173.633.1-36.2000110.8D315 R324P313-D315 PolarHBondContact O-N 2.95Å; P313-R324 HydrophobicContact CB-CB 3.73Å; P313-R324 HydrophobicContact CG-CB 4.23Å
314S63.3Low82.4Confident107 Ų10747.9 Ų47.975%0.74829%0.288SS*.  trans-75.8-10.8177540000113.4G312G312-S314 PolarHBondContact O-N 2.81Å
315D73.9Confident82.3Confident27 Ų2748.9 Ų48.914%0.14429%0.293CS..SBendtrans-93.8159.3-175-66-35.5000112.8S226 K228 P313 R324S226-D315 WeakPolarHBondContact O-CB 3.32Å; K228-D315 WeakPolarHBondContact CB-OD2 3.32Å; K228-D315 WeakPolarHBondContact CD-OD1 3.08Å; K228-D315 WeakPolarHBondContact CE-OD1 3.26Å; K228-D315 HydrophobicContact CG-CB 4.08Å; K228-D315 VanDerWaalsContact CG-CG 3.43Å; K228-D315 VanDerWaalsContact CG-OD1 3.32Å; K228-D315 WeakPolarHBondContact CG-OD1 3.11Å; K228-D315 PolarHBondContact N-OD2 3.47Å; K228-D315 IonicContact NZ-OD1 3.96Å; K228-D315 PolarHBondContact NZ-OD1 2.92Å; P313-D315 PolarHBondContact O-N 2.95Å; D315-R324 PolarHBondContact O-NH1 3.43Å; D315-R324 PolarHBondContact O-NH2 3.05Å
316A83.8Confident82Confident72 Ų7250 Ų5060%0.59530%0.304SS*.PPolyproline II helixtrans-64.2135174.500000109.7
317P87.1Confident82Confident82 Ų8252.8 Ų52.853%0.53232%0.317SS..PPolyproline II helixtrans-65.9137.9178.926.4-30.5000110.3
318Q89.9Confident82.5Confident97 Ų9754.9 Ų54.945%0.45333%0.326SS..PPolyproline II helixtrans-70158.3167.6-66.1-64.6-29.800110.2S226 F320 S321S226-Q318 WeakPolarHBondContact OG-CB 3.41Å; S226-Q318 PolarHBondContact OG-N 3.23Å; Q318-F320 HydrophobicContact CB-CD1 3.91Å; Q318-F320 HydrophobicContact CB-CD2 4.18Å; Q318-F320 HydrophobicContact CB-CE1 3.48Å; Q318-F320 VanDerWaalsContact CB-CE1 3.48Å; Q318-F320 HydrophobicContact CB-CE2 3.76Å; Q318-F320 HydrophobicContact CB-CG 4.25Å; Q318-F320 HydrophobicContact CB-CZ 3.39Å; Q318-F320 HydrophobicContact CG-CE1 3.96Å; Q318-F320 HydrophobicContact CG-CE2 4.36Å; Q318-F320 HydrophobicContact CG-CZ 3.69Å; Q318-F320 PolarHBondContact O-N 3.31Å; Q318-F320 VanDerWaalsContact O-N 3.09Å; Q318-S321 WeakPolarHBondContact O-CB 3.38Å; Q318-S321 PolarHBondContact O-N 3.17Å
319S91.3Very high83.6Confident84 Ų8449.6 Ų49.659%0.58730%0.301SS*.THydrogen-bonded Turntrans-60.8-24.9-174.964.40000113.6K284K284-S319 WeakPolarHBondContact CE-O 3.47Å; K284-S319 PolarHBondContact NZ-O 3.18Å
320F92.9Very high84.9Confident21 Ų2147.1 Ų47.19%0.09229%0.285CS..THydrogen-bonded Turntrans-84.5-10.1176.857.4-110.2000114.4Y224 M274 W275 I277 Q318Y224-F320 HydrophobicContact CD1-CD1 4.32Å; Y224-F320 HydrophobicContact CD1-CE1 4.08Å; Y224-F320 HydrophobicContact CD1-CZ 4.23Å; M274-F320 WeakPolarHBondContact CA-O 3.08Å; M274-F320 HydrophobicContact CB-CD2 4.47Å; M274-F320 HydrophobicContact CG-CD2 3.8Å; M274-F320 HydrophobicContact CG-CE2 4.27Å; W275-F320 PolarHBondContact N-O 3.11Å; I277-F320 HydrophobicContact CD1-CB 3.45Å; I277-F320 VanDerWaalsContact CD1-CB 3.45Å; I277-F320 HydrophobicContact CD1-CD1 3.83Å; I277-F320 HydrophobicContact CD1-CG 3.73Å; Q318-F320 HydrophobicContact CB-CD1 3.91Å; Q318-F320 HydrophobicContact CB-CD2 4.18Å; Q318-F320 HydrophobicContact CB-CE1 3.48Å; Q318-F320 VanDerWaalsContact CB-CE1 3.48Å; Q318-F320 HydrophobicContact CB-CE2 3.76Å; Q318-F320 HydrophobicContact CB-CG 4.25Å; Q318-F320 HydrophobicContact CB-CZ 3.39Å; Q318-F320 HydrophobicContact CG-CE1 3.96Å; Q318-F320 HydrophobicContact CG-CE2 4.36Å; Q318-F320 HydrophobicContact CG-CZ 3.69Å; Q318-F320 PolarHBondContact O-N 3.31Å; Q318-F320 VanDerWaalsContact O-N 3.09Å
321S94.5Very high86.4Confident16 Ų1643.3 Ų43.311%0.11227%0.267CS..EExtended strand (participates in β ladder)trans-69.9132.7178.7-163.80000110.7E272 W275 Q318 R324E272-S321 WeakPolarHBondContact OE1-CB 3.34Å; E272-S321 PolarHBondContact OE1-OG 3.11Å; W275-S321 PolarHBondContact NE1-O 3.35Å; Q318-S321 WeakPolarHBondContact O-CB 3.38Å; Q318-S321 PolarHBondContact O-N 3.17Å; S321-R324 WeakPolarHBondContact OG-CD 3.26Å; S321-R324 WeakPolarHBondContact OG-CG 3.19Å
322A95.4Very high87.7Confident24 Ų2443 Ų4320%0.19826%0.264CS..EExtended strand (participates in β ladder)trans-106.6-46.1175.400000111.5R273 W275R273-A322 WeakPolarHBondContact O-CA 3.24Å; R273-A322 WeakPolarHBondContact O-CB 3.2Å; R273-A322 PolarHBondContact O-N 3.33Å; W275-A322 HydrophobicContact CD2-CB 4.19Å; W275-A322 HydrophobicContact CG-CB 4.22Å
323T95.1Very high89.2Confident35 Ų3541.6 Ų41.622%0.21525%0.249CC..EExtended strand (participates in β ladder)trans-147143.4177.8-62.40000109.9E272 R273 L325 D357E272-T323 CarbonylContact C-O 3.42Å; E272-T323 WeakPolarHBondContact CA-O 3.27Å; R273-T323 PolarHBondContact N-O 3.09Å; R273-T323 PolarHBondContact NH2-OG1 3.44Å; R273-T323 PolarHBondContact O-N 3.3Å; R273-T323 VanDerWaalsContact O-N 3.07Å; T323-L325 HydrophobicContact CG2-CD2 4.45Å; T323-L325 HydrophobicContact CG2-CG 4.38Å; T323-D357 HydrophobicContact CG2-CB 3.9Å; T323-D357 PolarHBondContact OG1-OD1 3.04Å
324R92.9Very high90.7Very high56 Ų5642.5 Ų42.521%0.21125%0.248CC..EExtended strand (participates in β ladder)trans-138.5138.3177-63.1-177.6-57.71639.8109.9Y271 E272 P313 D315 S321Y271-R324 VanDerWaalsContact O-CA 3.28Å; Y271-R324 WeakPolarHBondContact O-CA 3.5Å; E272-R324 HydrophobicContact CB-CG 3.99Å; E272-R324 HydrophobicContact CG-CG 3.65Å; E272-R324 WeakPolarHBondContact OE1-CD 3.49Å; P313-R324 HydrophobicContact CB-CB 3.73Å; P313-R324 HydrophobicContact CG-CB 4.23Å; D315-R324 PolarHBondContact O-NH1 3.43Å; D315-R324 PolarHBondContact O-NH2 3.05Å; S321-R324 WeakPolarHBondContact OG-CD 3.26Å; S321-R324 WeakPolarHBondContact OG-CG 3.19Å
325L91.9Very high92.4Very high21 Ų2137.6 Ų37.611%0.1121%0.213CC..EExtended strand (participates in β ladder)trans-132.4146.5-178.1-58.2174.4000109.3T270 Y271 T323 F345 M356 D357T270-L325 PolarHBondContact OG1-O 3.48Å; Y271-L325 HydrophobicContact CD1-CB 3.92Å; Y271-L325 HydrophobicContact CD1-CD1 3.71Å; Y271-L325 HydrophobicContact CD1-CG 3.77Å; Y271-L325 HydrophobicContact CE1-CD1 4.02Å; Y271-L325 HydrophobicContact CE1-CG 4.34Å; Y271-L325 HydrophobicContact CG-CB 4.39Å; Y271-L325 HydrophobicContact CG-CD1 4.44Å; Y271-L325 PolarHBondContact N-O 3.5Å; Y271-L325 PolarHBondContact O-N 2.91Å; T323-L325 HydrophobicContact CG2-CD2 4.45Å; T323-L325 HydrophobicContact CG2-CG 4.38Å; L325-F345 HydrophobicContact CD1-CB 3.85Å; L325-F345 HydrophobicContact CD1-CD1 3.55Å; L325-F345 HydrophobicContact CD1-CE1 4.32Å; L325-F345 HydrophobicContact CD1-CG 3.83Å; L325-M356 HydrophobicContact CD1-CB 3.61Å; L325-M356 HydrophobicContact CD1-CE 4.39Å; L325-M356 HydrophobicContact CD1-SD 4.19Å; L325-M356 HydrophobicContact CD2-CE 3.67Å; L325-M356 HydrophobicContact CD2-SD 4.46Å; L325-D357 HydrophobicContact CD1-CB 4.14Å
326G88.3Confident93.5Very high24 Ų2439.8 Ų39.825%0.24722%0.22CC..  trans-113.529.9179.100000111.3H310H310-G326 PolarHBondContact CE1-O 2.86Å; H310-G326 PolarHBondContact NE2-O 3.24Å
327Q89.8Confident94Very high58 Ų5839.4 Ų39.427%0.27121%0.208SC..SBendtrans-99151.2176.7-77.272.325.100107.9F345 D347 M356Q327-F345 HydrophobicContact CB-CE1 3.82Å; Q327-F345 HydrophobicContact CB-CZ 4.48Å; Q327-F345 WeakPolarHBondContact O-CZ 3.26Å; Q327-D347 HydrophobicContact CB-CB 4.23Å; Q327-D347 HydrophobicContact CG-CB 4.34Å; Q327-D347 WeakPolarHBondContact CG-OD2 3.08Å; Q327-M356 HydrophobicContact CG-SD 4.12Å
328Y92.1Very high94.5Very high44 Ų4438.7 Ų38.717%0.17320%0.202CC..  trans-72.6148161.5-70.5-50.3000109.2S304 C307 T309 H310 D347 T348S304-Y328 CarbonylContact O-C 3.46Å; S304-Y328 WeakPolarHBondContact O-CA 3.12Å; S304-Y328 WeakPolarHBondContact O-CB 3.27Å; S304-Y328 VanDerWaalsContact O-CD1 3.26Å; S304-Y328 WeakPolarHBondContact O-CD1 3.22Å; C307-Y328 PolarHBondContact O-OH 3.21Å; T309-Y328 PolarHBondContact O-OH 3.08Å; T309-Y328 VanDerWaalsContact O-OH 3.1Å; H310-Y328 HydrophobicContact CB-CE1 4.1Å; H310-Y328 WeakPolarHBondContact CB-OH 3.16Å; H310-Y328 AromaticContact CG-CE1 3.94Å; H310-Y328 AromaticContact CG-CZ 3.9Å; H310-Y328 AromaticContact ND1-CD1 3.44Å; H310-Y328 WeakPolarHBondContact ND1-CD1 3.19Å; H310-Y328 AromaticContact ND1-CE1 3.12Å; H310-Y328 WeakPolarHBondContact ND1-CE1 3.41Å; H310-Y328 AromaticContact ND1-CZ 3.47Å; Y328-D347 WeakPolarHBondContact O-CA 3.32Å; Y328-T348 VanDerWaalsContact C-OG1 3.23Å; Y328-T348 PolarHBondContact O-N 3.2Å; Y328-T348 PolarHBondContact O-OG1 2.8Å
329G94Very high94.8Very high0 Ų035.8 Ų35.80%019%0.191CC..EExtended strand (participates in β ladder)trans169.3-170.7-177.200000115S304 A305 V346 T348S304-G329 CarbonylContact C-O 3.58Å; S304-G329 PolarHBondContact O-N 3.33Å; A305-G329 WeakPolarHBondContact CA-O 3.38Å; A305-G329 PolarHBondContact N-O 2.86Å; G329-V346 CarbonylContact C-O 3.6Å; G329-V346 WeakPolarHBondContact CA-O 3.45Å; G329-T348 PolarHBondContact N-OG1 3.12Å
330Y96.3Very high95.2Very high11 Ų1134.6 Ų34.64%0.04318%0.176CC..EExtended strand (participates in β ladder)trans-139.9155.617860.9-89000111A74 L91 F100 R332 V346 T348A74-Y330 HydrophobicContact CB-CD2 3.93Å; A74-Y330 HydrophobicContact CB-CE2 4.2Å; L91-Y330 HydrophobicContact CD2-CD1 4.08Å; L91-Y330 HydrophobicContact CD2-CD2 4.24Å; L91-Y330 HydrophobicContact CD2-CE1 4.1Å; L91-Y330 HydrophobicContact CD2-CE2 4.25Å; L91-Y330 HydrophobicContact CD2-CG 4.16Å; L91-Y330 HydrophobicContact CG-CD1 4.33Å; L91-Y330 HydrophobicContact CG-CE1 4.32Å; F100-Y330 HydrophobicContact CE1-CE2 4.12Å; F100-Y330 AromaticContact CZ-CE2 3.7Å; F100-Y330 HydrophobicContact CZ-CE2 3.7Å; F100-Y330 AromaticContact CZ-CZ 3.99Å; Y330-R332 HydrophobicContact CE2-CB 4.43Å; Y330-V346 HydrophobicContact CD1-CB 4.2Å; Y330-V346 HydrophobicContact CD2-CB 4.26Å; Y330-V346 HydrophobicContact CD2-CG2 4.25Å; Y330-V346 HydrophobicContact CE1-CB 3.82Å; Y330-V346 HydrophobicContact CE1-CG1 3.81Å; Y330-V346 HydrophobicContact CE2-CB 3.89Å; Y330-V346 HydrophobicContact CE2-CG1 4.42Å; Y330-V346 HydrophobicContact CE2-CG2 3.7Å; Y330-V346 HydrophobicContact CG-CB 4.4Å; Y330-V346 PolarHBondContact N-O 3.05Å; Y330-V346 VanDerWaalsContact N-O 3.16Å; Y330-V346 PolarHBondContact O-N 2.95Å; Y330-T348 HydrophobicContact CD1-CG2 3.83Å; Y330-T348 HydrophobicContact CE1-CG2 3.89Å
331T98.1Very high95.4Very high0 Ų033.6 Ų33.60%017%0.172CC..EExtended strand (participates in β ladder)trans-84.2122173.5-63.40000109.7A74 I75 L264 T302 T343 Y344A74-T331 CarbonylContact C-O 3.48Å; A74-T331 WeakPolarHBondContact CA-O 3.48Å; I75-T331 PolarHBondContact N-O 3.12Å; I75-T331 WeakPolarHBondContact O-CB 3.24Å; I75-T331 PolarHBondContact O-N 2.69Å; L264-T331 HydrophobicContact CD2-CG2 4.23Å; T302-T331 WeakPolarHBondContact CB-OG1 3.41Å; T302-T331 PolarHBondContact OG1-OG1 3.1Å; T331-T343 HydrophobicContact CG2-CG2 4Å; T331-Y344 CarbonylContact C-O 3.54Å; T331-Y344 WeakPolarHBondContact CA-O 3.22Å
332R97.8Very high95.6Very high43 Ų4332.8 Ų32.816%0.16217%0.166CC..EExtended strand (participates in β ladder)trans-93.4117.4168-173.1176.1-173.3179.45109.4A73 H99 F100 Y330 T343 Y344 V346A73-R332 CarbonylContact O-C 3.54Å; A73-R332 WeakPolarHBondContact O-CA 3.3Å; H99-R332 PolarHBondContact O-NH2 3.44Å; F100-R332 HydrophobicContact CE1-CG 4.25Å; Y330-R332 HydrophobicContact CE2-CB 4.43Å; R332-T343 CarbonylContact O-C 3.53Å; R332-T343 WeakPolarHBondContact O-CA 3.39Å; R332-Y344 PolarHBondContact N-O 3.19Å; R332-Y344 PolarHBondContact O-N 2.93Å; R332-V346 HydrophobicContact CB-CG2 3.99Å
333L98.5Very high95.7Very high2 Ų231.7 Ų31.71%0.0116%0.157CC..EExtended strand (participates in β ladder)trans-98.5139.1174.1171.970.5000110R72 A73 I75 F180 I216 V335 L341 T343R72-L333 CarbonylContact C-O 3.43Å; R72-L333 WeakPolarHBondContact CA-O 3.42Å; A73-L333 HydrophobicContact CB-CB 4.27Å; A73-L333 HydrophobicContact CB-CD2 4.43Å; A73-L333 PolarHBondContact N-O 2.9Å; A73-L333 PolarHBondContact O-N 3.37Å; I75-L333 HydrophobicContact CD1-CB 4.27Å; I75-L333 HydrophobicContact CD1-CD2 4.07Å; F180-L333 HydrophobicContact CE1-CD2 4.06Å; F180-L333 HydrophobicContact CZ-CD2 4.04Å; I216-L333 HydrophobicContact CD1-CD1 4.32Å; I216-L333 HydrophobicContact CD1-CD2 3.4Å; I216-L333 VanDerWaalsContact CD1-CD2 3.4Å; L333-V335 HydrophobicContact CD1-CG2 4.24Å; L333-V335 HydrophobicContact CD2-CG2 4.27Å; L333-V335 HydrophobicContact CG-CG2 4.21Å; L333-L341 HydrophobicContact CD1-CB 4.47Å; L333-L341 HydrophobicContact CD1-CD1 4.13Å; L333-L341 HydrophobicContact CD1-CD2 4.38Å; L333-T343 HydrophobicContact CB-CG2 4.42Å; L333-T343 HydrophobicContact CD1-CG2 3.81Å
334K98.1Very high95.8Very high69 Ų6931.8 Ų31.830%0.315%0.154SC..EExtended strand (participates in β ladder)trans-133.2123.3166.3-175.6168.2178.3-179.80110.5L71 R72 Y336 L341 S342L71-K334 CarbonylContact O-C 3.51Å; L71-K334 VanDerWaalsContact O-CA 3.27Å; L71-K334 WeakPolarHBondContact O-CA 3.43Å; R72-K334 HydrophobicContact CG-CD 4.45Å; R72-K334 HydrophobicContact CG-CG 4.36Å; K334-Y336 HydrophobicContact CB-CE2 4.3Å; K334-Y336 HydrophobicContact CD-CD1 4.14Å; K334-Y336 HydrophobicContact CD-CE1 3.48Å; K334-Y336 VanDerWaalsContact CD-CE1 3.48Å; K334-Y336 HydrophobicContact CD-CE2 4.46Å; K334-Y336 HydrophobicContact CG-CD1 4.26Å; K334-Y336 HydrophobicContact CG-CD2 4.5Å; K334-Y336 HydrophobicContact CG-CE1 3.92Å; K334-Y336 HydrophobicContact CG-CE2 4.14Å; K334-L341 CarbonylContact O-C 3.6Å; K334-L341 VanDerWaalsContact O-CA 3.26Å; K334-L341 WeakPolarHBondContact O-CA 3.41Å; K334-L341 WeakPolarHBondContact O-CB 3.11Å; K334-S342 PolarHBondContact N-O 3.25Å; K334-S342 PolarHBondContact O-N 3.07Å
335V98Very high95.9Very high3 Ų329.1 Ų29.12%0.01814%0.144CC..EExtended strand (participates in β ladder)trans-103.4113.5174.8179.80000107.6P70 L71 L177 W214 L333 L341P70-V335 CarbonylContact C-O 3.57Å; P70-V335 WeakPolarHBondContact CA-O 3.39Å; P70-V335 WeakPolarHBondContact CB-O 3.22Å; L71-V335 HydrophobicContact CB-CB 4.21Å; L71-V335 HydrophobicContact CD2-CG2 4.4Å; L71-V335 PolarHBondContact N-O 2.81Å; L71-V335 VanDerWaalsContact N-O 3.11Å; L71-V335 PolarHBondContact O-N 2.83Å; L177-V335 HydrophobicContact CB-CG1 4.39Å; W214-V335 HydrophobicContact CG-CG1 4.16Å; L333-V335 HydrophobicContact CD1-CG2 4.24Å; L333-V335 HydrophobicContact CD2-CG2 4.27Å; L333-V335 HydrophobicContact CG-CG2 4.21Å; V335-L341 HydrophobicContact CB-CB 4.42Å; V335-L341 HydrophobicContact CG2-CB 4.02Å; V335-L341 HydrophobicContact CG2-CD2 4.44Å
336Y97.1Very high96.1Very high74 Ų7428.2 Ų28.229%0.2914%0.139SC..  trans-85.9-41.9-172.1-61.7-91.2000112.2K334 H340 S342 Y360K334-Y336 HydrophobicContact CB-CE2 4.3Å; K334-Y336 HydrophobicContact CD-CD1 4.14Å; K334-Y336 HydrophobicContact CD-CE1 3.48Å; K334-Y336 VanDerWaalsContact CD-CE1 3.48Å; K334-Y336 HydrophobicContact CD-CE2 4.46Å; K334-Y336 HydrophobicContact CG-CD1 4.26Å; K334-Y336 HydrophobicContact CG-CD2 4.5Å; K334-Y336 HydrophobicContact CG-CE1 3.92Å; K334-Y336 HydrophobicContact CG-CE2 4.14Å; Y336-H340 HydrophobicContact CD2-CB 4.27Å; Y336-H340 PolarHBondContact N-O 2.89Å; Y336-S342 VanDerWaalsContact CE2-OG 3.23Å; Y336-S342 WeakPolarHBondContact CE2-OG 3.48Å; Y336-S342 PolarHBondContact OH-OG 2.79Å; Y336-Y360 HydrophobicContact CE2-CE1 4.36Å
337N96Very high96.3Very high64 Ų6427.2 Ų27.234%0.34213%0.128SC..SBendtrans-166.6-164.9-173.65744.2000109.2W214 T339 H340W214-N337 PolarHBondContact NE1-O 3.49Å; N337-T339 PolarHBondContact O-N 2.77Å; N337-T339 PolarHBondContact OD1-N 2.89Å; N337-T339 PolarHBondContact OD1-OG1 3.28Å; N337-H340 PolarHBondContact OD1-N 3.16Å
338T96.2Very high96.4Very high66 Ų6624.6 Ų24.641%0.40512%0.116SC..SBendtrans-69.5-16.9-177.562.90000114.3L177 Q213L177-T338 HydrophobicContact CD1-CG2 4.16Å; Q213-T338 HydrophobicContact CG-CG2 3.79Å
339T97.5Very high95.8Very high36 Ų3625.8 Ų25.822%0.22113%0.131CC..SBendtrans-116.8-24.4-171.855.20000113.6W214 N337 E362 K363W214-T339 VanDerWaalsContact CZ2-C 3.43Å; N337-T339 PolarHBondContact O-N 2.77Å; N337-T339 PolarHBondContact OD1-N 2.89Å; N337-T339 PolarHBondContact OD1-OG1 3.28Å; T339-E362 CarbonylContact O-C 3.53Å; T339-E362 WeakPolarHBondContact O-CA 3.4Å; T339-K363 WeakPolarHBondContact CA-O 3.43Å; T339-K363 WeakPolarHBondContact CB-O 3.16Å; T339-K363 VanDerWaalsContact CG2-O 3.28Å; T339-K363 WeakPolarHBondContact CG2-O 3.32Å; T339-K363 PolarHBondContact O-N 2.91Å
340H98.1Very high94.6Very high59 Ų5930.8 Ų30.827%0.27316%0.157SC..EExtended strand (participates in β ladder)trans-125.3131.9-177-6669.2000113.9Y336 N337 E362Y336-H340 HydrophobicContact CD2-CB 4.27Å; Y336-H340 PolarHBondContact N-O 2.89Å; N337-H340 PolarHBondContact OD1-N 3.16Å; H340-E362 IonicContact NE2-OE2 3.64Å
341L98.3Very high92.7Very high0 Ų040.1 Ų40.10%020%0.198CC..EExtended strand (participates in β ladder)trans-129.6163.4158.568.474.7000111W214 M262 L333 K334 V335 L361W214-L341 HydrophobicContact CD2-CD2 3.61Å; W214-L341 HydrophobicContact CD2-CG 4.35Å; W214-L341 HydrophobicContact CE3-CD2 3.33Å; W214-L341 HydrophobicContact CE3-CG 4.1Å; W214-L341 HydrophobicContact CG-CD2 4.19Å; W214-L341 HydrophobicContact CH2-CD2 4.15Å; W214-L341 HydrophobicContact CH2-CG 4Å; W214-L341 HydrophobicContact CZ2-CB 4.34Å; W214-L341 HydrophobicContact CZ2-CD2 4.37Å; W214-L341 HydrophobicContact CZ2-CG 4.25Å; W214-L341 HydrophobicContact CZ3-CD2 3.64Å; W214-L341 HydrophobicContact CZ3-CG 3.94Å; M262-L341 HydrophobicContact SD-CD1 3.61Å; M262-L341 HydrophobicContact SD-CD2 4.02Å; L333-L341 HydrophobicContact CD1-CB 4.47Å; L333-L341 HydrophobicContact CD1-CD1 4.13Å; L333-L341 HydrophobicContact CD1-CD2 4.38Å; K334-L341 CarbonylContact O-C 3.6Å; K334-L341 VanDerWaalsContact O-CA 3.26Å; K334-L341 WeakPolarHBondContact O-CA 3.41Å; K334-L341 WeakPolarHBondContact O-CB 3.11Å; V335-L341 HydrophobicContact CB-CB 4.42Å; V335-L341 HydrophobicContact CG2-CB 4.02Å; V335-L341 HydrophobicContact CG2-CD2 4.44Å; L341-L361 HydrophobicContact CD1-CB 3.59Å; L341-L361 HydrophobicContact CD1-CD2 4.36Å; L341-L361 HydrophobicContact CD2-CD2 4.47Å; L341-L361 HydrophobicContact CG-CB 3.98Å; L341-L361 PolarHBondContact N-O 2.71Å; L341-L361 PolarHBondContact O-N 2.86Å
342S98.4Very high90.7Very high0 Ų045.9 Ų45.90%023%0.233CC..EExtended strand (participates in β ladder)trans-139.3150.1171.964.80000112.3K334 Y336 Y344 F359K334-S342 PolarHBondContact N-O 3.25Å; K334-S342 PolarHBondContact O-N 3.07Å; Y336-S342 VanDerWaalsContact CE2-OG 3.23Å; Y336-S342 WeakPolarHBondContact CE2-OG 3.48Å; Y336-S342 PolarHBondContact OH-OG 2.79Å; S342-Y344 WeakPolarHBondContact OG-CE2 3.23Å; S342-F359 CarbonylContact C-O 3.55Å; S342-F359 WeakPolarHBondContact CA-O 3.34Å; S342-F359 VanDerWaalsContact CB-O 3.23Å; S342-F359 WeakPolarHBondContact CB-O 3.39Å
343T98.3Very high88.9Confident1 Ų145 Ų451%0.00624%0.237CC..EExtended strand (participates in β ladder)trans-119.5155.8164.663.80000112.1M262 I300 T331 R332 L333 F359M262-T343 HydrophobicContact CE-CG2 3.79Å; M262-T343 HydrophobicContact SD-CG2 4.39Å; I300-T343 HydrophobicContact CD1-CG2 4.12Å; T331-T343 HydrophobicContact CG2-CG2 4Å; R332-T343 CarbonylContact O-C 3.53Å; R332-T343 WeakPolarHBondContact O-CA 3.39Å; L333-T343 HydrophobicContact CB-CG2 4.42Å; L333-T343 HydrophobicContact CD1-CG2 3.81Å; T343-F359 PolarHBondContact N-O 3.01Å; T343-F359 PolarHBondContact O-N 3.23Å; T343-F359 WeakPolarHBondContact OG1-CD1 3.42Å
344Y95.8Very high88.1Confident37 Ų3748.7 Ų48.715%0.14526%0.257CS..EExtended strand (participates in β ladder)trans-138.5141.4168.3-52.8-103000107.8T331 R332 S342 F355 K358 Y360T331-Y344 CarbonylContact C-O 3.54Å; T331-Y344 WeakPolarHBondContact CA-O 3.22Å; R332-Y344 PolarHBondContact N-O 3.19Å; R332-Y344 PolarHBondContact O-N 2.93Å; S342-Y344 WeakPolarHBondContact OG-CE2 3.23Å; Y344-F355 HydrophobicContact CD1-CB 4.32Å; Y344-F355 HydrophobicContact CG-CD1 4.37Å; Y344-K358 HydrophobicContact CD1-CB 3.71Å; Y344-K358 HydrophobicContact CD1-CD 4.4Å; Y344-K358 HydrophobicContact CD1-CG 3.84Å; Y344-K358 HydrophobicContact CE1-CB 3.66Å; Y344-K358 HydrophobicContact CE1-CD 3.51Å; Y344-K358 VanDerWaalsContact CE1-CE 3.4Å; Y344-K358 HydrophobicContact CE1-CG 3.25Å; Y344-K358 WeakPolarHBondContact OH-CE 3.4Å; Y344-Y360 PolarHBondContact OH-OH 2.85Å
345F96.4Very high87.7Confident0 Ų050.7 Ų50.70%027%0.266CS..EExtended strand (participates in β ladder)trans-82.3127.1163.5-175-100.6000109.1Y271 S304 L325 Q327 M356Y271-F345 HydrophobicContact CD1-CD2 4.39Å; Y271-F345 HydrophobicContact CD1-CG 4.43Å; Y271-F345 HydrophobicContact CD2-CB 4.28Å; Y271-F345 AromaticContact CD2-CD2 3.2Å; Y271-F345 HydrophobicContact CD2-CD2 3.2Å; Y271-F345 AromaticContact CD2-CE2 3.7Å; Y271-F345 HydrophobicContact CD2-CE2 3.7Å; Y271-F345 AromaticContact CD2-CG 3.96Å; Y271-F345 HydrophobicContact CD2-CG 3.96Å; Y271-F345 HydrophobicContact CE1-CB 4.3Å; Y271-F345 HydrophobicContact CE2-CB 4Å; Y271-F345 AromaticContact CE2-CD2 3.66Å; Y271-F345 HydrophobicContact CE2-CD2 3.66Å; Y271-F345 HydrophobicContact CE2-CG 4.18Å; Y271-F345 AromaticContact CG-CD2 3.61Å; Y271-F345 HydrophobicContact CG-CD2 3.61Å; Y271-F345 AromaticContact CG-CE2 3.91Å; Y271-F345 HydrophobicContact CG-CE2 3.91Å; Y271-F345 HydrophobicContact CG-CG 4.07Å; S304-F345 WeakPolarHBondContact OG-CE2 3.47Å; L325-F345 HydrophobicContact CD1-CB 3.85Å; L325-F345 HydrophobicContact CD1-CD1 3.55Å; L325-F345 HydrophobicContact CD1-CE1 4.32Å; L325-F345 HydrophobicContact CD1-CG 3.83Å; Q327-F345 HydrophobicContact CB-CE1 3.82Å; Q327-F345 HydrophobicContact CB-CZ 4.48Å; Q327-F345 WeakPolarHBondContact O-CZ 3.26Å; F345-M356 HydrophobicContact CB-CB 4.36Å; F345-M356 HydrophobicContact CD1-CB 4.31Å; F345-M356 PolarHBondContact N-O 3.4Å; F345-M356 PolarHBondContact O-N 3.34Å
346V95.2Very high87.5Confident1 Ų152.7 Ų52.71%0.00628%0.275CS..EExtended strand (participates in β ladder)trans-101.7112.4176.6-175.60000108.2G329 Y330 R332 F355G329-V346 CarbonylContact C-O 3.6Å; G329-V346 WeakPolarHBondContact CA-O 3.45Å; Y330-V346 HydrophobicContact CD1-CB 4.2Å; Y330-V346 HydrophobicContact CD2-CB 4.26Å; Y330-V346 HydrophobicContact CD2-CG2 4.25Å; Y330-V346 HydrophobicContact CE1-CB 3.82Å; Y330-V346 HydrophobicContact CE1-CG1 3.81Å; Y330-V346 HydrophobicContact CE2-CB 3.89Å; Y330-V346 HydrophobicContact CE2-CG1 4.42Å; Y330-V346 HydrophobicContact CE2-CG2 3.7Å; Y330-V346 HydrophobicContact CG-CB 4.4Å; Y330-V346 PolarHBondContact N-O 3.05Å; Y330-V346 VanDerWaalsContact N-O 3.16Å; Y330-V346 PolarHBondContact O-N 2.95Å; R332-V346 HydrophobicContact CB-CG2 3.99Å; V346-F355 HydrophobicContact CG2-CD1 3.98Å; V346-F355 HydrophobicContact CG2-CE1 3.9Å
347D93.2Very high87.4Confident4 Ų450.3 Ų50.32%0.02127%0.268CS..EExtended strand (participates in β ladder)trans-72.2125.5176.2176.910.4000111Q327 Y328 S349 N354 M356Q327-D347 HydrophobicContact CB-CB 4.23Å; Q327-D347 HydrophobicContact CG-CB 4.34Å; Q327-D347 WeakPolarHBondContact CG-OD2 3.08Å; Y328-D347 WeakPolarHBondContact O-CA 3.32Å; D347-S349 VanDerWaalsContact OD1-CB 3.31Å; D347-S349 WeakPolarHBondContact OD1-CB 3.48Å; D347-S349 PolarHBondContact OD1-N 2.88Å; D347-S349 PolarHBondContact OD1-OG 3Å; D347-S349 PolarHBondContact OD2-OG 2.93Å; D347-N354 HydrophobicContact CB-CB 4.27Å; D347-N354 PolarHBondContact N-O 3.12Å; D347-N354 VanDerWaalsContact N-O 3.11Å; D347-M356 HydrophobicContact CB-SD 4.04Å
348T91.1Very high87.4Confident2 Ų252.5 Ų52.51%0.01227%0.274CS..  trans-104-4.3179.861.50000114P86 S87 Q90 Y328 G329 Y330P86-T348 VanDerWaalsContact CB-O 3.22Å; P86-T348 WeakPolarHBondContact CB-O 2.98Å; S87-T348 WeakPolarHBondContact OG-CB 3.38Å; S87-T348 PolarHBondContact OG-OG1 3.18Å; Q90-T348 HydrophobicContact CB-CG2 4.28Å; Q90-T348 HydrophobicContact CG-CG2 4.44Å; Y328-T348 VanDerWaalsContact C-OG1 3.23Å; Y328-T348 PolarHBondContact O-N 3.2Å; Y328-T348 PolarHBondContact O-OG1 2.8Å; G329-T348 PolarHBondContact N-OG1 3.12Å; Y330-T348 HydrophobicContact CD1-CG2 3.83Å; Y330-T348 HydrophobicContact CE1-CG2 3.89Å
349S78.8Confident87.5Confident70 Ų7049.3 Ų49.349%0.4926%0.255SS..SBendtrans-75.7-28.8179.169.10000113.7D347D347-S349 VanDerWaalsContact OD1-CB 3.31Å; D347-S349 WeakPolarHBondContact OD1-CB 3.48Å; D347-S349 PolarHBondContact OD1-N 2.88Å; D347-S349 PolarHBondContact OD1-OG 3Å; D347-S349 PolarHBondContact OD2-OG 2.93Å
350D68.9Low87.5Confident104 Ų10450.7 Ų50.756%0.55626%0.256SS*.SBendtrans-99167.5177.7-83.5-28.2000113.5Q90 V352Q90-D350 PolarHBondContact NE2-O 2.58Å; D350-V352 PolarHBondContact O-N 3.03Å
351K55.9Low87.5Confident208 Ų20848 Ų4890%0.90424%0.244SC*.SBendtrans-70.4100.7176-67.3-175.4-178.51790110.6
352V56.6Low87.5Confident121 Ų12149.1 Ų49.173%0.73325%0.249SC*.SBendtrans65109.8170.1-172.30000116.2D350 N354D350-V352 PolarHBondContact O-N 3.03Å; V352-N354 PolarHBondContact O-N 3.35Å
353G60.3Low87.3Confident23 Ų2351.3 Ų51.324%0.23726%0.259CS..  trans71.232.9140.100000117.6F355G353-F355 VanDerWaalsContact O-CD2 3.31Å; G353-F355 WeakPolarHBondContact O-CD2 3.23Å; G353-F355 WeakPolarHBondContact O-CE2 3.48Å; G353-F355 PolarHBondContact O-N 2.97Å
354N81.8Confident86.9Confident81 Ų8158.3 Ų58.343%0.43330%0.296SS..EExtended strand (participates in β ladder)trans-73.2109.5171.6-167.816.2000109.7D347 V352 M356D347-N354 HydrophobicContact CB-CB 4.27Å; D347-N354 PolarHBondContact N-O 3.12Å; D347-N354 VanDerWaalsContact N-O 3.11Å; V352-N354 PolarHBondContact O-N 3.35Å; N354-M356 PolarHBondContact O-N 2.78Å
355F89.6Confident86.5Confident110 Ų11059.4 Ų59.448%0.48230%0.304SS..EExtended strand (participates in β ladder)trans-82.3113178-64.3-78000109.7Y344 V346 G353Y344-F355 HydrophobicContact CD1-CB 4.32Å; Y344-F355 HydrophobicContact CG-CD1 4.37Å; V346-F355 HydrophobicContact CG2-CD1 3.98Å; V346-F355 HydrophobicContact CG2-CE1 3.9Å; G353-F355 VanDerWaalsContact O-CD2 3.31Å; G353-F355 WeakPolarHBondContact O-CD2 3.23Å; G353-F355 WeakPolarHBondContact O-CE2 3.48Å; G353-F355 PolarHBondContact O-N 2.97Å
356M94.3Very high86Confident45 Ų4562.5 Ų62.522%0.22232%0.32CS..EExtended strand (participates in β ladder)trans-109.7163.8176.8-53.4-174.980.400110.3L325 Q327 F345 D347 N354 K358L325-M356 HydrophobicContact CD1-CB 3.61Å; L325-M356 HydrophobicContact CD1-CE 4.39Å; L325-M356 HydrophobicContact CD1-SD 4.19Å; L325-M356 HydrophobicContact CD2-CE 3.67Å; L325-M356 HydrophobicContact CD2-SD 4.46Å; Q327-M356 HydrophobicContact CG-SD 4.12Å; F345-M356 HydrophobicContact CB-CB 4.36Å; F345-M356 HydrophobicContact CD1-CB 4.31Å; F345-M356 PolarHBondContact N-O 3.4Å; F345-M356 PolarHBondContact O-N 3.34Å; D347-M356 HydrophobicContact CB-SD 4.04Å; N354-M356 PolarHBondContact O-N 2.78Å; M356-K358 PolarHBondContact O-N 3.3Å
357D95.4Very high85.5Confident25 Ų2565.9 Ų65.913%0.13434%0.337CS..EExtended strand (participates in β ladder)trans41.560.1177.5-164.726.2000115Y271 R273 T323 L325 F359Y271-D357 HydrophobicContact CE1-CB 3.95Å; Y271-D357 VanDerWaalsContact CE1-OD2 3.24Å; Y271-D357 WeakPolarHBondContact CE1-OD2 3.36Å; Y271-D357 PolarHBondContact OH-OD2 3.36Å; R273-D357 WeakPolarHBondContact CB-OD2 3.38Å; R273-D357 IonicContact CZ-OD1 3.88Å; R273-D357 IonicContact CZ-OD2 2.83Å; R273-D357 IonicContact NE-OD1 2.69Å; R273-D357 PolarHBondContact NE-OD1 3.41Å; R273-D357 IonicContact NE-OD2 3.49Å; R273-D357 PolarHBondContact NE-OD2 3.06Å; R273-D357 IonicContact NH2-OD1 2.86Å; R273-D357 PolarHBondContact NH2-OD1 3.1Å; R273-D357 IonicContact NH2-OD2 3.82Å; T323-D357 HydrophobicContact CG2-CB 3.9Å; T323-D357 PolarHBondContact OG1-OD1 3.04Å; L325-D357 HydrophobicContact CD1-CB 4.14Å; D357-F359 PolarHBondContact O-N 2.77Å
358K96Very high85Confident109 Ų10969.5 Ų69.547%0.47436%0.356SS..EExtended strand (participates in β ladder)trans-63.8115.8172.4176.9173.8-153.3-151.70109.5Y344 M356 Y360Y344-K358 HydrophobicContact CD1-CB 3.71Å; Y344-K358 HydrophobicContact CD1-CD 4.4Å; Y344-K358 HydrophobicContact CD1-CG 3.84Å; Y344-K358 HydrophobicContact CE1-CB 3.66Å; Y344-K358 HydrophobicContact CE1-CD 3.51Å; Y344-K358 VanDerWaalsContact CE1-CE 3.4Å; Y344-K358 HydrophobicContact CE1-CG 3.25Å; Y344-K358 WeakPolarHBondContact OH-CE 3.4Å; M356-K358 PolarHBondContact O-N 3.3Å; K358-Y360 HydrophobicContact CD-CE2 3.94Å; K358-Y360 VanDerWaalsContact CE-CZ 3.49Å; K358-Y360 WeakPolarHBondContact CE-OH 2.92Å; K358-Y360 HydrophobicContact CG-CD2 4.4Å; K358-Y360 HydrophobicContact CG-CE2 3.84Å; K358-Y360 PolarHBondContact NZ-OH 3Å
359F96.8Very high84.6Confident0 Ų073.8 Ų73.80%038%0.377CS..EExtended strand (participates in β ladder)trans-125.9135.6-177.8169.8-117.4000111.1M262 G289 I291 V298 S342 T343 D357 L361M262-F359 HydrophobicContact CE-CE1 4.43Å; G289-F359 CarbonylContact O-C 3.58Å; G289-F359 WeakPolarHBondContact O-CA 3.29Å; I291-F359 HydrophobicContact CB-CE2 3.92Å; I291-F359 HydrophobicContact CB-CZ 4.14Å; I291-F359 HydrophobicContact CG1-CE2 3.54Å; I291-F359 HydrophobicContact CG1-CZ 4.02Å; V298-F359 HydrophobicContact CB-CZ 4.5Å; V298-F359 HydrophobicContact CG1-CE1 3.93Å; V298-F359 HydrophobicContact CG1-CZ 4.05Å; V298-F359 HydrophobicContact CG2-CE1 4.49Å; V298-F359 HydrophobicContact CG2-CZ 4.02Å; S342-F359 CarbonylContact C-O 3.55Å; S342-F359 WeakPolarHBondContact CA-O 3.34Å; S342-F359 VanDerWaalsContact CB-O 3.23Å; S342-F359 WeakPolarHBondContact CB-O 3.39Å; T343-F359 PolarHBondContact N-O 3.01Å; T343-F359 PolarHBondContact O-N 3.23Å; T343-F359 WeakPolarHBondContact OG1-CD1 3.42Å; D357-F359 PolarHBondContact O-N 2.77Å; F359-L361 HydrophobicContact CE1-CB 3.98Å; F359-L361 HydrophobicContact CZ-CB 3.85Å; F359-L361 HydrophobicContact CZ-CD1 4.34Å
360Y98.1Very high85Confident64 Ų6474 Ų7425%0.25137%0.369SS..EExtended strand (participates in β ladder)trans-116.4132.7172.3-70.9-86000111G289 H290 I291 Y336 Y344 K358G289-Y360 PolarHBondContact O-N 2.93Å; H290-Y360 WeakPolarHBondContact CA-O 3.46Å; I291-Y360 PolarHBondContact N-O 2.71Å; Y336-Y360 HydrophobicContact CE2-CE1 4.36Å; Y344-Y360 PolarHBondContact OH-OH 2.85Å; K358-Y360 HydrophobicContact CD-CE2 3.94Å; K358-Y360 VanDerWaalsContact CE-CZ 3.49Å; K358-Y360 WeakPolarHBondContact CE-OH 2.92Å; K358-Y360 HydrophobicContact CG-CD2 4.4Å; K358-Y360 HydrophobicContact CG-CE2 3.84Å; K358-Y360 PolarHBondContact NZ-OH 3Å
361L98.4Very high86.2Confident4 Ų471.9 Ų71.92%0.02136%0.356CS..EExtended strand (participates in β ladder)trans-113.2123.1168.2-176.861000108.4W214 D261 M262 I291 A294 V298 L341 F359W214-L361 HydrophobicContact CH2-CG 4.38Å; W214-L361 HydrophobicContact CZ3-CD2 3.88Å; W214-L361 HydrophobicContact CZ3-CG 4.02Å; D261-L361 HydrophobicContact CB-CD2 4.1Å; M262-L361 HydrophobicContact CG-CD2 3.88Å; M262-L361 HydrophobicContact SD-CD2 4.42Å; I291-L361 HydrophobicContact CB-CD1 4Å; I291-L361 HydrophobicContact CG2-CD1 3.81Å; I291-L361 WeakPolarHBondContact O-CA 3.42Å; A294-L361 HydrophobicContact CB-CD1 3.88Å; V298-L361 HydrophobicContact CG2-CD1 4.29Å; L341-L361 HydrophobicContact CD1-CB 3.59Å; L341-L361 HydrophobicContact CD1-CD2 4.36Å; L341-L361 HydrophobicContact CD2-CD2 4.47Å; L341-L361 HydrophobicContact CG-CB 3.98Å; L341-L361 PolarHBondContact N-O 2.71Å; L341-L361 PolarHBondContact O-N 2.86Å; F359-L361 HydrophobicContact CE1-CB 3.98Å; F359-L361 HydrophobicContact CZ-CB 3.85Å; F359-L361 HydrophobicContact CZ-CD1 4.34Å
362E97.9Very high88.5Confident23 Ų2361.4 Ų61.411%0.10731%0.314CS..EExtended strand (participates in β ladder)trans-118.3140.5179.7-179.2-175.2155.800110H290 I291 R292 N293 T339 H340H290-E362 IonicContact CE1-OE2 3.43Å; H290-E362 PolarHBondContact CE1-OE2 3.29Å; H290-E362 IonicContact NE2-OE2 3.15Å; H290-E362 PolarHBondContact NE2-OE2 2.99Å; I291-E362 PolarHBondContact O-N 2.95Å; R292-E362 CarbonylContact C-O 3.52Å; R292-E362 WeakPolarHBondContact CA-O 3.31Å; R292-E362 HydrophobicContact CB-CB 4.35Å; R292-E362 WeakPolarHBondContact CD-OE1 3.37Å; R292-E362 HydrophobicContact CG-CB 4.3Å; R292-E362 HydrophobicContact CG-CG 4.14Å; R292-E362 IonicContact CZ-OE1 3.69Å; R292-E362 VanDerWaalsContact CZ-OE1 3.24Å; R292-E362 IonicContact NE-OE1 3.22Å; R292-E362 PolarHBondContact NE-OE1 3.07Å; R292-E362 IonicContact NH1-OE1 3.85Å; R292-E362 PolarHBondContact NH1-OE1 2.79Å; R292-E362 IonicContact NH2-OE1 3.25Å; N293-E362 PolarHBondContact N-O 3.35Å; T339-E362 CarbonylContact O-C 3.53Å; T339-E362 WeakPolarHBondContact O-CA 3.4Å; H340-E362 IonicContact NE2-OE2 3.64Å
363K95.4Very high91.2Very high45 Ų4556.4 Ų56.420%0.19628%0.279CS..  trans-139.3148167.163.6-175.5174.6-171.50111.6Q213 W214 D261 N293 T339Q213-K363 WeakPolarHBondContact O-CE 3.3Å; Q213-K363 PolarHBondContact O-NZ 3.5Å; W214-K363 HydrophobicContact CE3-CD 4.4Å; W214-K363 HydrophobicContact CH2-CD 3.98Å; W214-K363 HydrophobicContact CH2-CG 3.77Å; W214-K363 HydrophobicContact CZ2-CG 4.26Å; W214-K363 HydrophobicContact CZ3-CD 3.88Å; W214-K363 HydrophobicContact CZ3-CG 4.19Å; D261-K363 IonicContact OD1-NZ 3.41Å; D261-K363 PolarHBondContact OD1-NZ 2.8Å; D261-K363 IonicContact OD2-NZ 3.21Å; D261-K363 PolarHBondContact OD2-NZ 3.21Å; N293-K363 WeakPolarHBondContact OD1-CA 3.48Å; T339-K363 WeakPolarHBondContact CA-O 3.43Å; T339-K363 WeakPolarHBondContact CB-O 3.16Å; T339-K363 VanDerWaalsContact CG2-O 3.28Å; T339-K363 WeakPolarHBondContact CG2-O 3.32Å; T339-K363 PolarHBondContact O-N 2.91Å
364D89.8Confident94Very high148 Ų14859.5 Ų59.579%0.79128%0.283SS*.  trans-76.60-179.5-64.2-28.3000113.7R292 N293R292-D364 IonicContact CZ-OD1 3.74Å; R292-D364 IonicContact NE-OD1 3.8Å; R292-D364 PolarHBondContact NE-OD1 2.84Å; R292-D364 IonicContact NH2-OD1 3.24Å; R292-D364 PolarHBondContact NH2-OD1 2.8Å; R292-D364 IonicContact NH2-OD2 2.76Å; N293-D364 VanDerWaalsContact ND2-CG 3.34Å; N293-D364 PolarHBondContact ND2-OD2 3.35Å; N293-D364 PolarHBondContact OD1-N 2.68Å

Retrieved 364 of 364 residues in 679.8 ms (Link to these results)