A0A078BS14_CAEEL Loading...

Frizzled-4

AlphaFold DB , UniProt , Accession A0A078BS14, Species CAEEL (Caenorhabditis elegans), Gene lin-17, Length 490 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.2	Very low	73.5	Confident	214 Å²	214	99.1 Å²	99.1	100%	1.054	49%	0.485	S	S	*	.				0	124.8	0	-87.9	163.5	156.8	0	0	108.4
2	K	45.9	Very low	75	Confident	214 Å²	214	90.8 Å²	90.8	93%	0.93	45%	0.445	S	S	*	.			trans	-106.2	64.8	175.6	-76.9	-175.6	176.8	179.1	0	109.3
3	T	57.9	Low	76.1	Confident	62 Å²	62	88.1 Å²	88.1	38%	0.38	43%	0.432	S	S	.	.			trans	-91.2	108.8	172.7	43.1	0	0	0	0	108.2	C5 I46	T3-C5 PolarHBondContact O-N 3.05Å; T3-C5 VanDerWaalsContact O-N 3.16Å; T3-I46 HydrophobicContact CG2-CG2 4.19Å
4	K	70.4	Confident	77	Confident	208 Å²	208	85.7 Å²	85.7	90%	0.904	43%	0.428	S	S	*	.			trans	-83.1	39.2	176.5	-66.5	-171.8	176.7	-174.8	0	111.9
5	C	84.3	Confident	77.7	Confident	26 Å²	26	80.6 Å²	80.6	18%	0.176	40%	0.404	C	S	.	.	S	Bend	trans	-68.3	-38	-172.4	48.3	0	0	0	0	113.4	T3 C43 I46	T3-C5 PolarHBondContact O-N 3.05Å; T3-C5 VanDerWaalsContact O-N 3.16Å; C5-C43 HydrophobicContact CB-CB 3.78Å; C5-C43 WeakPolarHBondContact CB-SG 3.4Å; C5-C43 WeakPolarHBondContact SG-CB 3.37Å; C5-C43 CovalentContact SG-SG 2.02Å; C5-C43 PolarHBondContact SG-SG 3.42Å; C5-I46 HydrophobicContact CB-CD1 3.61Å
6	H	84.9	Confident	78.4	Confident	19 Å²	19	77.3 Å²	77.3	9%	0.088	39%	0.389	C	S	.	.	S	Bend	trans	-136.3	141.2	177.5	-169.3	-83	0	0	0	109.6	H8 I9 Q38 V39 D42	H6-H8 AromaticContact CE1-CD2 3.49Å; H6-H8 PolarHBondContact CE1-CD2 3.18Å; H6-H8 VanDerWaalsContact CE1-CD2 3.49Å; H6-H8 AromaticContact CE1-CG 3.84Å; H6-H8 AromaticContact ND1-CG 3.97Å; H6-H8 PolarHBondContact ND1-N 3.17Å; H6-H8 PolarHBondContact O-N 2.96Å; H6-I9 HydrophobicContact CB-CB 4.42Å; H6-I9 WeakPolarHBondContact O-CB 3.47Å; H6-I9 WeakPolarHBondContact O-CG2 3.4Å; H6-I9 PolarHBondContact O-N 3.27Å; H6-I9 VanDerWaalsContact O-N 3.1Å; H6-Q38 PolarHBondContact CD2-O 3.42Å; H6-V39 HydrophobicContact CB-CG2 4.29Å; H6-D42 HydrophobicContact CB-CB 4.06Å; H6-D42 IonicContact CD2-OD2 3.62Å; H6-D42 PolarHBondContact CD2-OD2 3.38Å; H6-D42 IonicContact NE2-OD2 2.67Å
7	P	82.4	Confident	79	Confident	103 Å²	103	81 Å²	81	67%	0.669	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54.4	-37.1	178	-27.2	34.8	0	0	0	113.5
8	H	85.3	Confident	79.5	Confident	22 Å²	22	80.6 Å²	80.6	10%	0.102	41%	0.413	C	S	.	.	T	Hydrogen-bonded Turn	trans	-91.4	8.2	-179.2	-51.7	-42.3	0	0	0	115.2	H6 H10 F11 F12 V35 V39 P73	H6-H8 AromaticContact CE1-CD2 3.49Å; H6-H8 PolarHBondContact CE1-CD2 3.18Å; H6-H8 VanDerWaalsContact CE1-CD2 3.49Å; H6-H8 AromaticContact CE1-CG 3.84Å; H6-H8 AromaticContact ND1-CG 3.97Å; H6-H8 PolarHBondContact ND1-N 3.17Å; H6-H8 PolarHBondContact O-N 2.96Å; H8-H10 VanDerWaalsContact C-N 3.28Å; H8-H10 PolarHBondContact O-N 3.4Å; H8-F11 PolarHBondContact O-N 3.44Å; H8-F12 WeakPolarHBondContact O-CB 3.31Å; H8-F12 PolarHBondContact O-N 3.49Å; H8-V35 HydrophobicContact CB-CG1 4.48Å; H8-V39 HydrophobicContact CB-CG2 4.31Å; H8-P73 HydrophobicContact CB-CG 4.24Å; H8-P73 VanDerWaalsContact CD2-CG 3.49Å; H8-P73 WeakPolarHBondContact CD2-CG 3.38Å
9	I	87.9	Confident	79.8	Confident	35 Å²	35	78.9 Å²	78.9	18%	0.179	41%	0.408	C	S	.	.	H	α-helix	trans	-57.9	-41.4	-178.9	-175.9	58.9	0	0	0	112.1	H6 F12 I13 V39	H6-I9 HydrophobicContact CB-CB 4.42Å; H6-I9 WeakPolarHBondContact O-CB 3.47Å; H6-I9 WeakPolarHBondContact O-CG2 3.4Å; H6-I9 PolarHBondContact O-N 3.27Å; H6-I9 VanDerWaalsContact O-N 3.1Å; I9-F12 PolarHBondContact O-N 3.26Å; I9-I13 HydrophobicContact CD1-CD1 4.37Å; I9-I13 HydrophobicContact CD1-CG1 3.9Å; I9-I13 HydrophobicContact CG1-CG1 4.36Å; I9-I13 WeakPolarHBondContact O-CB 3.34Å; I9-I13 VanDerWaalsContact O-CG1 3.25Å; I9-I13 WeakPolarHBondContact O-CG1 3.32Å; I9-I13 PolarHBondContact O-N 3.13Å; I9-V39 HydrophobicContact CB-CG1 4.38Å; I9-V39 HydrophobicContact CD1-CG1 3.34Å; I9-V39 HydrophobicContact CG1-CG1 4.41Å
10	H	85.4	Confident	79.8	Confident	145 Å²	145	80.7 Å²	80.7	67%	0.671	42%	0.416	S	S	*	.	H	α-helix	trans	-68.6	-45.9	-179.3	-169.8	-96	0	0	0	111.2	H8 F12 I13 C14	H8-H10 VanDerWaalsContact C-N 3.28Å; H8-H10 PolarHBondContact O-N 3.4Å; H10-F12 VanDerWaalsContact C-N 3.34Å; H10-F12 PolarHBondContact O-N 3.41Å; H10-I13 PolarHBondContact O-N 3.16Å; H10-C14 WeakPolarHBondContact O-CB 3.26Å; H10-C14 PolarHBondContact O-N 3.04Å; H10-C14 PolarHBondContact O-SG 3.48Å; H10-C14 VanDerWaalsContact O-SG 3.33Å
11	F	87.4	Confident	79.9	Confident	42 Å²	42	81.4 Å²	81.4	18%	0.184	43%	0.427	C	S	.	.	H	α-helix	trans	-56.5	-48	174.4	172.2	-90.8	0	0	0	111.6	H8 S15 V35 M71 P73	H8-F11 PolarHBondContact O-N 3.44Å; F11-S15 WeakPolarHBondContact O-CB 3.12Å; F11-S15 PolarHBondContact O-N 3.42Å; F11-S15 PolarHBondContact O-OG 3.05Å; F11-V35 HydrophobicContact CD1-CG1 4.28Å; F11-V35 HydrophobicContact CE1-CG1 4.39Å; F11-M71 HydrophobicContact CE2-CG 4.23Å; F11-M71 HydrophobicContact CE2-SD 4.01Å; F11-M71 HydrophobicContact CZ-CB 3.96Å; F11-M71 HydrophobicContact CZ-CG 3.7Å; F11-M71 HydrophobicContact CZ-SD 3.97Å; F11-P73 HydrophobicContact CD1-CB 4.25Å; F11-P73 HydrophobicContact CD1-CG 4.3Å; F11-P73 HydrophobicContact CD2-CB 4.49Å; F11-P73 HydrophobicContact CE1-CB 4.39Å; F11-P73 HydrophobicContact CE1-CG 4.37Å; F11-P73 HydrophobicContact CG-CB 4.3Å
12	F	90.6	Very high	81.8	Confident	0 Å²	0	74.1 Å²	74.1	0%	0	40%	0.396	C	S	.	.	H	α-helix	trans	-61.5	-53.3	-179.7	174.7	-115.1	0	0	0	111.6	H8 I9 H10 C14 S15 V16 V35 C36 V39 W54 L58 F63	H8-F12 WeakPolarHBondContact O-CB 3.31Å; H8-F12 PolarHBondContact O-N 3.49Å; I9-F12 PolarHBondContact O-N 3.26Å; H10-F12 VanDerWaalsContact C-N 3.34Å; H10-F12 PolarHBondContact O-N 3.41Å; F12-C14 VanDerWaalsContact C-N 3.35Å; F12-C14 PolarHBondContact O-N 3.4Å; F12-S15 PolarHBondContact O-N 3.06Å; F12-S15 VanDerWaalsContact O-N 3.1Å; F12-V16 HydrophobicContact CD2-CG2 4.19Å; F12-V16 HydrophobicContact CE2-CG2 3.76Å; F12-V16 HydrophobicContact CZ-CG2 3.97Å; F12-V16 WeakPolarHBondContact O-CG2 3.13Å; F12-V16 PolarHBondContact O-N 2.98Å; F12-V16 VanDerWaalsContact O-N 3.08Å; F12-V35 HydrophobicContact CB-CG1 4.41Å; F12-C36 HydrophobicContact CD2-CB 4.31Å; F12-C36 HydrophobicContact CE2-CB 3.47Å; F12-C36 VanDerWaalsContact CE2-CB 3.47Å; F12-C36 HydrophobicContact CZ-CB 3.73Å; F12-C36 WeakPolarHBondContact CZ-SG 3.28Å; F12-V39 HydrophobicContact CB-CG2 3.99Å; F12-V39 HydrophobicContact CD1-CB 4.19Å; F12-V39 HydrophobicContact CD1-CG1 3.79Å; F12-V39 HydrophobicContact CD1-CG2 4.49Å; F12-V39 HydrophobicContact CE1-CG1 4.43Å; F12-V39 HydrophobicContact CG-CB 4.42Å; F12-V39 HydrophobicContact CG-CG1 4.39Å; F12-V39 HydrophobicContact CG-CG2 4.3Å; F12-W54 HydrophobicContact CE1-CZ2 4.2Å; F12-L58 HydrophobicContact CE1-CB 4.38Å; F12-L58 HydrophobicContact CE1-CD2 3.86Å; F12-L58 HydrophobicContact CE1-CG 4.48Å; F12-L58 HydrophobicContact CZ-CB 4.47Å; F12-L58 HydrophobicContact CZ-CD2 4.14Å; F12-F63 HydrophobicContact CE2-CD2 4.32Å; F12-F63 AromaticContact CE2-CE2 3.84Å; F12-F63 HydrophobicContact CE2-CE2 3.84Å; F12-F63 HydrophobicContact CE2-CZ 4.04Å; F12-F63 AromaticContact CZ-CE2 3.81Å; F12-F63 HydrophobicContact CZ-CE2 3.81Å; F12-F63 HydrophobicContact CZ-CZ 4.1Å
13	I	90.1	Very high	83.1	Confident	55 Å²	55	72.8 Å²	72.8	28%	0.282	40%	0.397	S	S	.	.	H	α-helix	trans	-60.7	-42.9	-179.3	-66	-64.5	0	0	0	111.5	I9 H10 S15 V16 F17 L58	I9-I13 HydrophobicContact CD1-CD1 4.37Å; I9-I13 HydrophobicContact CD1-CG1 3.9Å; I9-I13 HydrophobicContact CG1-CG1 4.36Å; I9-I13 WeakPolarHBondContact O-CB 3.34Å; I9-I13 VanDerWaalsContact O-CG1 3.25Å; I9-I13 WeakPolarHBondContact O-CG1 3.32Å; I9-I13 PolarHBondContact O-N 3.13Å; H10-I13 PolarHBondContact O-N 3.16Å; I13-S15 VanDerWaalsContact C-N 3.33Å; I13-S15 PolarHBondContact O-N 3.23Å; I13-V16 PolarHBondContact O-N 3.41Å; I13-F17 HydrophobicContact CD1-CE2 4.45Å; I13-F17 HydrophobicContact CG2-CD2 3.85Å; I13-F17 HydrophobicContact CG2-CE2 4.22Å; I13-F17 WeakPolarHBondContact O-CD2 3.27Å; I13-F17 PolarHBondContact O-N 3.01Å; I13-L58 HydrophobicContact CD1-CD1 3.85Å; I13-L58 HydrophobicContact CD1-CD2 3.9Å
14	C	87.9	Confident	83.8	Confident	55 Å²	55	73.8 Å²	73.8	37%	0.372	42%	0.42	S	S	.	.	H	α-helix	trans	-63	-39.2	175.7	-72	0	0	0	0	112.2	H10 F12 V16 A18	H10-C14 WeakPolarHBondContact O-CB 3.26Å; H10-C14 PolarHBondContact O-N 3.04Å; H10-C14 PolarHBondContact O-SG 3.48Å; H10-C14 VanDerWaalsContact O-SG 3.33Å; F12-C14 VanDerWaalsContact C-N 3.35Å; F12-C14 PolarHBondContact O-N 3.4Å; C14-V16 VanDerWaalsContact C-N 3.27Å; C14-V16 PolarHBondContact O-N 3.32Å; C14-A18 CarbonylContact O-C 3.59Å; C14-A18 VanDerWaalsContact O-CA 3.28Å; C14-A18 WeakPolarHBondContact O-CA 3.47Å; C14-A18 WeakPolarHBondContact O-CB 3.27Å; C14-A18 PolarHBondContact O-N 3.46Å
15	S	87.8	Confident	84	Confident	9 Å²	9	68.4 Å²	68.4	6%	0.063	40%	0.399	C	S	.	.	H	α-helix	trans	-69.2	-22.9	178.7	-58.9	0	0	0	0	113.7	F11 F12 I13 T30	F11-S15 WeakPolarHBondContact O-CB 3.12Å; F11-S15 PolarHBondContact O-N 3.42Å; F11-S15 PolarHBondContact O-OG 3.05Å; F12-S15 PolarHBondContact O-N 3.06Å; F12-S15 VanDerWaalsContact O-N 3.1Å; I13-S15 VanDerWaalsContact C-N 3.33Å; I13-S15 PolarHBondContact O-N 3.23Å; S15-T30 PolarHBondContact O-OG1 2.96Å
16	V	89.3	Confident	83.3	Confident	27 Å²	27	74 Å²	74	16%	0.164	44%	0.435	C	S	.	.	H	α-helix	trans	-85.8	-48.4	176.5	178.7	0	0	0	0	111.5	F12 I13 C14 L58 F63	F12-V16 HydrophobicContact CD2-CG2 4.19Å; F12-V16 HydrophobicContact CE2-CG2 3.76Å; F12-V16 HydrophobicContact CZ-CG2 3.97Å; F12-V16 WeakPolarHBondContact O-CG2 3.13Å; F12-V16 PolarHBondContact O-N 2.98Å; F12-V16 VanDerWaalsContact O-N 3.08Å; I13-V16 PolarHBondContact O-N 3.41Å; C14-V16 VanDerWaalsContact C-N 3.27Å; C14-V16 PolarHBondContact O-N 3.32Å; V16-L58 HydrophobicContact CB-CD2 4.35Å; V16-L58 HydrophobicContact CG1-CD2 4.08Å; V16-L58 HydrophobicContact CG2-CD2 4.25Å; V16-F63 HydrophobicContact CB-CZ 4.48Å; V16-F63 HydrophobicContact CG1-CE1 4.43Å; V16-F63 HydrophobicContact CG1-CZ 4.2Å; V16-F63 HydrophobicContact CG2-CE1 3.62Å; V16-F63 HydrophobicContact CG2-CE2 4.49Å; V16-F63 HydrophobicContact CG2-CZ 3.45Å; V16-F63 VanDerWaalsContact CG2-CZ 3.45Å
17	F	88.7	Confident	82.8	Confident	141 Å²	141	80.5 Å²	80.5	62%	0.618	47%	0.465	S	S	*	.	H	α-helix	trans	-89.9	-18.3	-174.3	-68.7	-75.5	0	0	0	114.2	I13 L58	I13-F17 HydrophobicContact CD1-CE2 4.45Å; I13-F17 HydrophobicContact CG2-CD2 3.85Å; I13-F17 HydrophobicContact CG2-CE2 4.22Å; I13-F17 WeakPolarHBondContact O-CD2 3.27Å; I13-F17 PolarHBondContact O-N 3.01Å; F17-L58 HydrophobicContact CE2-CD2 4.16Å
18	A	87.9	Confident	82.7	Confident	73 Å²	73	77.3 Å²	77.3	60%	0.603	45%	0.448	S	S	*	.	S	Bend	trans	-137.7	62.9	177.8	0	0	0	0	0	111.1	C14	C14-A18 CarbonylContact O-C 3.59Å; C14-A18 VanDerWaalsContact O-CA 3.28Å; C14-A18 WeakPolarHBondContact O-CA 3.47Å; C14-A18 WeakPolarHBondContact O-CB 3.27Å; C14-A18 PolarHBondContact O-N 3.46Å
19	P	84.6	Confident	82.7	Confident	49 Å²	49	77 Å²	77	32%	0.318	45%	0.447	S	S	.	.			trans	-68.4	157.5	-177	30.9	-36.6	0	0	0	112	A28 V29	P19-A28 HydrophobicContact CB-CB 3.81Å; P19-A28 HydrophobicContact CG-CB 3.66Å; P19-V29 WeakPolarHBondContact CB-O 3.41Å
20	M	79.3	Confident	82.7	Confident	114 Å²	114	76.6 Å²	76.6	56%	0.562	45%	0.447	S	S	*	.	B	Isolated β-bridge	trans	-81.6	139.2	176.8	-64.7	-171.2	-152.5	0	0	110.8	P22 A28 V29 M71	M20-P22 WeakPolarHBondContact O-CD 3.42Å; M20-A28 CarbonylContact O-C 3.22Å; M20-A28 WeakPolarHBondContact O-CA 3.45Å; M20-V29 PolarHBondContact N-O 2.85Å; M20-V29 PolarHBondContact O-N 2.69Å; M20-M71 HydrophobicContact CB-CE 4.1Å; M20-M71 HydrophobicContact CE-CE 3.27Å; M20-M71 HydrophobicContact CE-SD 3.47Å; M20-M71 WeakPolarHBondContact CE-SD 3.42Å; M20-M71 HydrophobicContact CG-CE 3.72Å; M20-M71 HydrophobicContact SD-CE 3.4Å; M20-M71 WeakPolarHBondContact SD-CE 3.41Å; M20-M71 HydrophobicContact SD-SD 4.41Å
21	C	83.3	Confident	83	Confident	97 Å²	97	69.7 Å²	69.7	66%	0.655	42%	0.415	S	S	*	.			trans	-117.4	92.2	176.2	-63.9	0	0	0	0	110.5	A28	C21-A28 VanDerWaalsContact SG-CB 3.5Å
22	P	77.6	Confident	83.3	Confident	60 Å²	60	67.8 Å²	67.8	39%	0.39	41%	0.406	S	S	.	.			trans	-64.4	140.2	176.2	-18.1	30.9	0	0	0	111.7	M20 G24 M25 V29	M20-P22 WeakPolarHBondContact O-CD 3.42Å; P22-G24 PolarHBondContact O-N 3.13Å; P22-M25 PolarHBondContact O-N 2.89Å; P22-V29 HydrophobicContact CG-CG2 3.95Å
23	I	71.8	Confident	83.4	Confident	186 Å²	186	71 Å²	71	95%	0.954	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.8	120.1	177.6	-60.2	166.5	0	0	0	108.7
24	G	73.8	Confident	83.4	Confident	83 Å²	83	69.7 Å²	69.7	86%	0.856	42%	0.416	S	S	*	.	T	Hydrogen-bonded Turn	trans	102.9	0.4	-179.6	0	0	0	0	0	115.4	P22	P22-G24 PolarHBondContact O-N 3.13Å
25	M	74.3	Confident	83.5	Confident	96 Å²	96	67.2 Å²	67.2	47%	0.473	40%	0.4	S	S	.	.			trans	-111.7	130.6	173.9	-160	160.6	-83.3	0	0	110.4	P22 Q27 V29 L69	P22-M25 PolarHBondContact O-N 2.89Å; M25-Q27 PolarHBondContact O-N 3.05Å; M25-V29 HydrophobicContact SD-CG2 4.37Å; M25-L69 HydrophobicContact CE-CD2 4.01Å; M25-L69 HydrophobicContact SD-CD2 3.74Å
26	P	69	Low	83.8	Confident	144 Å²	144	66.8 Å²	66.8	94%	0.935	40%	0.397	S	S	*	.	S	Bend	trans	-74.4	-13.9	-177	28.6	-34.3	0	0	0	113.6
27	Q	74.3	Confident	84	Confident	154 Å²	154	70.3 Å²	70.3	72%	0.72	41%	0.411	S	S	*	.	S	Bend	trans	-122.7	142.3	-176.5	-168.7	173.6	3.5	0	0	111.1	M25	M25-Q27 PolarHBondContact O-N 3.05Å
28	A	81.5	Confident	84.1	Confident	37 Å²	37	68.1 Å²	68.1	31%	0.306	40%	0.403	S	S	.	.			trans	-71.3	140.1	175.4	0	0	0	0	0	111.1	P19 M20 C21	P19-A28 HydrophobicContact CB-CB 3.81Å; P19-A28 HydrophobicContact CG-CB 3.66Å; M20-A28 CarbonylContact O-C 3.22Å; M20-A28 WeakPolarHBondContact O-CA 3.45Å; C21-A28 VanDerWaalsContact SG-CB 3.5Å
29	V	84.9	Confident	84.2	Confident	14 Å²	14	64.7 Å²	64.7	9%	0.085	37%	0.374	C	S	.	.	B	Isolated β-bridge	trans	-85.5	117.6	178.2	-176.1	0	0	0	0	109	P19 M20 P22 M25 L69 M71	P19-V29 WeakPolarHBondContact CB-O 3.41Å; M20-V29 PolarHBondContact N-O 2.85Å; M20-V29 PolarHBondContact O-N 2.69Å; P22-V29 HydrophobicContact CG-CG2 3.95Å; M25-V29 HydrophobicContact SD-CG2 4.37Å; V29-L69 HydrophobicContact CG1-CD2 4.41Å; V29-L69 HydrophobicContact CG1-CG 4.1Å; V29-L69 HydrophobicContact CG2-CD2 3.56Å; V29-L69 HydrophobicContact CG2-CG 4.12Å; V29-M71 HydrophobicContact CG1-CE 4.36Å
30	T	88.2	Confident	84.6	Confident	28 Å²	28	65.8 Å²	65.8	17%	0.172	37%	0.374	C	S	.	.			trans	-109.3	-176.3	-179.4	-167.2	0	0	0	0	111.8	S15 F63 P64 M71	S15-T30 PolarHBondContact O-OG1 2.96Å; T30-F63 HydrophobicContact CG2-CD1 3.74Å; T30-F63 HydrophobicContact CG2-CE1 4.24Å; T30-P64 HydrophobicContact CG2-CG 4.4Å; T30-M71 PolarHBondContact O-N 2.84Å
31	S	91.9	Very high	85.1	Confident	0 Å²	0	64 Å²	64	0%	0	38%	0.377	C	S	.	.	B	Isolated β-bridge	trans	-68.1	149.6	-179.3	-159.4	0	0	0	0	111.9	F63 M71	S31-F63 WeakPolarHBondContact O-CB 3.3Å; S31-M71 PolarHBondContact OG-O 3.1Å
32	C	92.1	Very high	85.4	Confident	1 Å²	1	63.4 Å²	63.4	1%	0.007	37%	0.367	C	S	.	.			trans	-69.5	148.2	172.1	-58.6	0	0	0	0	111.7	S34 V35 C36 P64 C70 M71 K72	C32-S34 PolarHBondContact O-N 3.48Å; C32-V35 HydrophobicContact CB-CG2 4.4Å; C32-V35 PolarHBondContact O-N 2.71Å; C32-C36 PolarHBondContact O-N 3.15Å; C32-P64 WeakPolarHBondContact CA-O 3.48Å; C32-C70 VanDerWaalsContact CA-SG 3.57Å; C32-C70 HydrophobicContact CB-CB 3.84Å; C32-C70 WeakPolarHBondContact CB-SG 3.28Å; C32-C70 WeakPolarHBondContact SG-CB 3.5Å; C32-C70 CovalentContact SG-SG 2.02Å; C32-C70 PolarHBondContact SG-SG 3.48Å; C32-M71 PolarHBondContact N-O 3.01Å; C32-M71 PolarHBondContact SG-N 3.42Å; C32-K72 HydrophobicContact CB-CG 3.96Å; C32-K72 VanDerWaalsContact SG-CE 3.51Å; C32-K72 WeakPolarHBondContact SG-CG 3.36Å
33	K	93.1	Very high	85.9	Confident	67 Å²	67	60.8 Å²	60.8	29%	0.291	35%	0.35	S	S	.	.	H	α-helix	trans	-55	-38.9	175.3	172.3	173.6	173.2	-161.6	0	112.7	V35 C36 E37 C60 F63 P64 D65	K33-V35 PolarHBondContact O-N 3.23Å; K33-C36 WeakPolarHBondContact O-CB 3.33Å; K33-C36 PolarHBondContact O-N 2.98Å; K33-C36 VanDerWaalsContact O-N 3.14Å; K33-E37 WeakPolarHBondContact CE-OE1 3.38Å; K33-E37 HydrophobicContact CG-CG 4.35Å; K33-E37 WeakPolarHBondContact O-CG 3.42Å; K33-E37 PolarHBondContact O-N 2.89Å; K33-C60 WeakPolarHBondContact CG-O 3.45Å; K33-F63 HydrophobicContact CB-CB 3.99Å; K33-F63 WeakPolarHBondContact CB-O 3.3Å; K33-P64 PolarHBondContact N-O 2.93Å; K33-D65 WeakPolarHBondContact CD-OD2 3.44Å
34	S	89.9	Confident	86.7	Confident	29 Å²	29	55.4 Å²	55.4	20%	0.203	32%	0.32	C	S	.	.	H	α-helix	trans	-56.3	-34.5	175.1	72.6	0	0	0	0	114.3	C32 Q38 D65 K72	C32-S34 PolarHBondContact O-N 3.48Å; S34-Q38 VanDerWaalsContact O-CG 3.29Å; S34-Q38 WeakPolarHBondContact O-CG 3.34Å; S34-Q38 PolarHBondContact O-N 2.87Å; S34-D65 PolarHBondContact N-OD1 3.23Å; S34-K72 VanDerWaalsContact OG-CE 3.27Å; S34-K72 WeakPolarHBondContact OG-CE 3.2Å; S34-K72 PolarHBondContact OG-NZ 3.26Å
35	V	90.4	Very high	87.3	Confident	3 Å²	3	54.9 Å²	54.9	2%	0.018	30%	0.304	C	S	.	.	H	α-helix	trans	-77	-39.4	179.1	-179.8	0	0	0	0	110.4	H8 F11 F12 C32 K33 E37 Q38 V39 K72	H8-V35 HydrophobicContact CB-CG1 4.48Å; F11-V35 HydrophobicContact CD1-CG1 4.28Å; F11-V35 HydrophobicContact CE1-CG1 4.39Å; F12-V35 HydrophobicContact CB-CG1 4.41Å; C32-V35 HydrophobicContact CB-CG2 4.4Å; C32-V35 PolarHBondContact O-N 2.71Å; K33-V35 PolarHBondContact O-N 3.23Å; V35-E37 VanDerWaalsContact C-N 3.33Å; V35-E37 PolarHBondContact O-N 3.22Å; V35-Q38 PolarHBondContact O-N 2.68Å; V35-V39 HydrophobicContact CG1-CG2 4.45Å; V35-V39 WeakPolarHBondContact O-CG2 3.33Å; V35-V39 PolarHBondContact O-N 3.35Å; V35-K72 HydrophobicContact CG2-CB 4.31Å; V35-K72 HydrophobicContact CG2-CG 4.08Å
36	C	93.9	Very high	87.8	Confident	0 Å²	0	52.8 Å²	52.8	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-58.1	-46.3	173.4	-177.4	0	0	0	0	111.6	F12 C32 K33 Q38 V39 K40 L58 C60 F63	F12-C36 HydrophobicContact CD2-CB 4.31Å; F12-C36 HydrophobicContact CE2-CB 3.47Å; F12-C36 VanDerWaalsContact CE2-CB 3.47Å; F12-C36 HydrophobicContact CZ-CB 3.73Å; F12-C36 WeakPolarHBondContact CZ-SG 3.28Å; C32-C36 PolarHBondContact O-N 3.15Å; K33-C36 WeakPolarHBondContact O-CB 3.33Å; K33-C36 PolarHBondContact O-N 2.98Å; K33-C36 VanDerWaalsContact O-N 3.14Å; C36-Q38 PolarHBondContact O-N 3.27Å; C36-V39 PolarHBondContact O-N 2.9Å; C36-K40 VanDerWaalsContact O-CB 3.23Å; C36-K40 WeakPolarHBondContact O-CB 3.39Å; C36-K40 PolarHBondContact O-N 2.95Å; C36-L58 PolarHBondContact SG-O 2.92Å; C36-C60 HydrophobicContact CB-CB 3.75Å; C36-C60 WeakPolarHBondContact CB-SG 3.44Å; C36-C60 PolarHBondContact O-SG 3.28Å; C36-C60 WeakPolarHBondContact SG-CA 3.43Å; C36-C60 WeakPolarHBondContact SG-CB 3.41Å; C36-C60 CovalentContact SG-SG 2.05Å; C36-C60 PolarHBondContact SG-SG 3.41Å; C36-F63 HydrophobicContact CB-CD2 3.7Å; C36-F63 HydrophobicContact CB-CE2 4.09Å
37	E	93.2	Very high	88.4	Confident	100 Å²	100	47.9 Å²	47.9	47%	0.467	26%	0.259	S	S	.	.	H	α-helix	trans	-63.9	-40.2	-177.9	-71.6	179.4	167.9	0	0	112.1	K33 V35 K40 A41 C60	K33-E37 WeakPolarHBondContact CE-OE1 3.38Å; K33-E37 HydrophobicContact CG-CG 4.35Å; K33-E37 WeakPolarHBondContact O-CG 3.42Å; K33-E37 PolarHBondContact O-N 2.89Å; V35-E37 VanDerWaalsContact C-N 3.33Å; V35-E37 PolarHBondContact O-N 3.22Å; E37-K40 PolarHBondContact O-N 2.86Å; E37-A41 WeakPolarHBondContact O-CB 3.19Å; E37-A41 PolarHBondContact O-N 3.05Å; E37-C60 HydrophobicContact CG-CB 3.96Å
38	Q	90.5	Very high	88.9	Confident	96 Å²	96	46.7 Å²	46.7	45%	0.449	25%	0.254	S	S	.	.	H	α-helix	trans	-63.6	-48.1	174.5	-70.8	171.1	12.3	0	0	111.9	H6 S34 V35 C36 K40 A41 D42	H6-Q38 PolarHBondContact CD2-O 3.42Å; S34-Q38 VanDerWaalsContact O-CG 3.29Å; S34-Q38 WeakPolarHBondContact O-CG 3.34Å; S34-Q38 PolarHBondContact O-N 2.87Å; V35-Q38 PolarHBondContact O-N 2.68Å; C36-Q38 PolarHBondContact O-N 3.27Å; Q38-K40 VanDerWaalsContact C-N 3.33Å; Q38-K40 PolarHBondContact O-N 2.94Å; Q38-A41 PolarHBondContact O-N 3.18Å; Q38-D42 PolarHBondContact O-N 3.31Å
39	V	91.7	Very high	89	Confident	0 Å²	0	52.4 Å²	52.4	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-65.4	-38.8	178.9	173.5	0	0	0	0	111.3	H6 H8 I9 F12 V35 C36 D42 C43 W54	H6-V39 HydrophobicContact CB-CG2 4.29Å; H8-V39 HydrophobicContact CB-CG2 4.31Å; I9-V39 HydrophobicContact CB-CG1 4.38Å; I9-V39 HydrophobicContact CD1-CG1 3.34Å; I9-V39 HydrophobicContact CG1-CG1 4.41Å; F12-V39 HydrophobicContact CB-CG2 3.99Å; F12-V39 HydrophobicContact CD1-CB 4.19Å; F12-V39 HydrophobicContact CD1-CG1 3.79Å; F12-V39 HydrophobicContact CD1-CG2 4.49Å; F12-V39 HydrophobicContact CE1-CG1 4.43Å; F12-V39 HydrophobicContact CG-CB 4.42Å; F12-V39 HydrophobicContact CG-CG1 4.39Å; F12-V39 HydrophobicContact CG-CG2 4.3Å; V35-V39 HydrophobicContact CG1-CG2 4.45Å; V35-V39 WeakPolarHBondContact O-CG2 3.33Å; V35-V39 PolarHBondContact O-N 3.35Å; C36-V39 PolarHBondContact O-N 2.9Å; V39-D42 PolarHBondContact O-N 3.38Å; V39-C43 WeakPolarHBondContact O-CB 3.29Å; V39-C43 PolarHBondContact O-N 2.87Å; V39-C43 PolarHBondContact O-SG 3.44Å; V39-C43 VanDerWaalsContact O-SG 3.34Å; V39-W54 HydrophobicContact CG1-CH2 4.48Å
40	K	92.1	Very high	89	Confident	73 Å²	73	58.8 Å²	58.8	32%	0.317	30%	0.301	S	S	.	.	H	α-helix	trans	-62.9	-44.1	175.4	-176.9	177.1	179.6	-175.4	0	111.3	C36 E37 Q38 D42 F44 W54	C36-K40 VanDerWaalsContact O-CB 3.23Å; C36-K40 WeakPolarHBondContact O-CB 3.39Å; C36-K40 PolarHBondContact O-N 2.95Å; E37-K40 PolarHBondContact O-N 2.86Å; Q38-K40 VanDerWaalsContact C-N 3.33Å; Q38-K40 PolarHBondContact O-N 2.94Å; K40-D42 VanDerWaalsContact C-N 3.29Å; K40-D42 PolarHBondContact O-N 3.2Å; K40-F44 HydrophobicContact CG-CB 4.38Å; K40-F44 WeakPolarHBondContact O-CB 3.29Å; K40-F44 PolarHBondContact O-N 3.02Å; K40-W54 HydrophobicContact CB-CD2 4.39Å; K40-W54 HydrophobicContact CB-CE3 4.44Å; K40-W54 HydrophobicContact CB-CH2 3.75Å; K40-W54 HydrophobicContact CB-CZ2 3.68Å; K40-W54 HydrophobicContact CB-CZ3 4.13Å; K40-W54 HydrophobicContact CD-CD2 3.97Å; K40-W54 HydrophobicContact CD-CG 4.09Å; K40-W54 HydrophobicContact CD-CZ2 4.38Å; K40-W54 HydrophobicContact CG-CD2 3.75Å; K40-W54 HydrophobicContact CG-CE3 3.9Å; K40-W54 HydrophobicContact CG-CG 4.33Å; K40-W54 HydrophobicContact CG-CH2 4.12Å; K40-W54 HydrophobicContact CG-CZ2 3.98Å; K40-W54 HydrophobicContact CG-CZ3 4.08Å
41	A	89.9	Confident	88.8	Confident	75 Å²	75	60.9 Å²	60.9	62%	0.62	33%	0.329	S	S	*	.	H	α-helix	trans	-56.6	-43.5	179.5	0	0	0	0	0	112.2	E37 Q38	E37-A41 WeakPolarHBondContact O-CB 3.19Å; E37-A41 PolarHBondContact O-N 3.05Å; Q38-A41 PolarHBondContact O-N 3.18Å
42	D	88.5	Confident	88.5	Confident	85 Å²	85	64.7 Å²	64.7	46%	0.455	35%	0.348	S	S	.	.	H	α-helix	trans	-88.2	-27.5	-174.5	-72.7	6.5	0	0	0	113.8	H6 Q38 V39 K40	H6-D42 HydrophobicContact CB-CB 4.06Å; H6-D42 IonicContact CD2-OD2 3.62Å; H6-D42 PolarHBondContact CD2-OD2 3.38Å; H6-D42 IonicContact NE2-OD2 2.67Å; Q38-D42 PolarHBondContact O-N 3.31Å; V39-D42 PolarHBondContact O-N 3.38Å; K40-D42 VanDerWaalsContact C-N 3.29Å; K40-D42 PolarHBondContact O-N 3.2Å
43	C	89.7	Confident	88.3	Confident	5 Å²	5	67.1 Å²	67.1	3%	0.034	37%	0.374	C	S	.	.	H	α-helix	trans	-101.9	-14.7	-174.1	-60.9	0	0	0	0	114.5	C5 V39 S45 I46 L47	C5-C43 HydrophobicContact CB-CB 3.78Å; C5-C43 WeakPolarHBondContact CB-SG 3.4Å; C5-C43 WeakPolarHBondContact SG-CB 3.37Å; C5-C43 CovalentContact SG-SG 2.02Å; C5-C43 PolarHBondContact SG-SG 3.42Å; V39-C43 WeakPolarHBondContact O-CB 3.29Å; V39-C43 PolarHBondContact O-N 2.87Å; V39-C43 PolarHBondContact O-SG 3.44Å; V39-C43 VanDerWaalsContact O-SG 3.34Å; C43-S45 PolarHBondContact O-N 3.14Å; C43-I46 PolarHBondContact O-N 2.74Å; C43-L47 PolarHBondContact O-N 3.44Å
44	F	88.9	Confident	88.2	Confident	73 Å²	73	65.8 Å²	65.8	32%	0.32	37%	0.367	S	S	.	.	H	α-helix	trans	-65.2	-39.2	-175.9	179.5	-109	0	0	0	112.9	K40 I46 L47 E48 W54	K40-F44 HydrophobicContact CG-CB 4.38Å; K40-F44 WeakPolarHBondContact O-CB 3.29Å; K40-F44 PolarHBondContact O-N 3.02Å; F44-I46 VanDerWaalsContact C-N 3.26Å; F44-I46 PolarHBondContact O-N 3.37Å; F44-L47 PolarHBondContact O-N 3.05Å; F44-L47 VanDerWaalsContact O-N 3.08Å; F44-E48 PolarHBondContact O-N 3.01Å; F44-W54 HydrophobicContact CB-CE3 4.42Å; F44-W54 HydrophobicContact CD2-CB 3.87Å; F44-W54 HydrophobicContact CD2-CE3 4.05Å; F44-W54 HydrophobicContact CE2-CB 3.81Å
45	S	84.9	Confident	88.1	Confident	72 Å²	72	66.5 Å²	66.5	50%	0.503	37%	0.371	S	S	.	.	H	α-helix	trans	-58.5	-36.8	178	55	0	0	0	0	112.9	C43 E48 E49	C43-S45 PolarHBondContact O-N 3.14Å; S45-E48 PolarHBondContact O-N 3.37Å; S45-E49 PolarHBondContact O-N 3.5Å
46	I	85	Confident	88.1	Confident	52 Å²	52	73.7 Å²	73.7	27%	0.267	40%	0.404	S	S	.	.	H	α-helix	trans	-69.1	-40.6	176.6	-56.6	-170.6	0	0	0	110.8	T3 C5 C43 F44 E48 E49 F50	T3-I46 HydrophobicContact CG2-CG2 4.19Å; C5-I46 HydrophobicContact CB-CD1 3.61Å; C43-I46 PolarHBondContact O-N 2.74Å; F44-I46 VanDerWaalsContact C-N 3.26Å; F44-I46 PolarHBondContact O-N 3.37Å; I46-E48 VanDerWaalsContact C-N 3.29Å; I46-E48 PolarHBondContact O-N 3.37Å; I46-E49 WeakPolarHBondContact O-CB 3.23Å; I46-E49 PolarHBondContact O-N 3.42Å; I46-F50 HydrophobicContact CG2-CD2 4.45Å; I46-F50 HydrophobicContact CG2-CE2 4.2Å; I46-F50 VanDerWaalsContact O-CD2 3.26Å; I46-F50 WeakPolarHBondContact O-CD2 3.47Å
47	L	82.9	Confident	87.7	Confident	41 Å²	41	77 Å²	77	22%	0.215	43%	0.426	C	S	.	.	H	α-helix	trans	-65.6	-36.5	178.5	-69.5	171.2	0	0	0	111.5	C43 F44 E49 F50 G51 I52 W54	C43-L47 PolarHBondContact O-N 3.44Å; F44-L47 PolarHBondContact O-N 3.05Å; F44-L47 VanDerWaalsContact O-N 3.08Å; L47-E49 PolarHBondContact O-N 3.3Å; L47-F50 PolarHBondContact O-N 3.46Å; L47-G51 PolarHBondContact O-N 3.47Å; L47-I52 CarbonylContact C-O 3.38Å; L47-I52 VanDerWaalsContact C-O 3.24Å; L47-I52 WeakPolarHBondContact CB-O 3.47Å; L47-I52 HydrophobicContact CD2-CG2 4.44Å; L47-I52 PolarHBondContact O-N 3.28Å; L47-I52 VanDerWaalsContact O-O 3.1Å; L47-W54 HydrophobicContact CD1-CE3 3.58Å; L47-W54 HydrophobicContact CD1-CZ3 3.71Å
48	E	84.4	Confident	87.6	Confident	129 Å²	129	73 Å²	73	60%	0.603	41%	0.408	S	S	*	.	H	α-helix	trans	-64.7	-36.5	176.2	-167.9	173.4	-118.6	0	0	112.6	F44 S45 I46 F50 G51	F44-E48 PolarHBondContact O-N 3.01Å; S45-E48 PolarHBondContact O-N 3.37Å; I46-E48 VanDerWaalsContact C-N 3.29Å; I46-E48 PolarHBondContact O-N 3.37Å; E48-F50 PolarHBondContact O-N 3.47Å; E48-G51 PolarHBondContact O-N 2.91Å
49	E	84	Confident	87.6	Confident	157 Å²	157	71.5 Å²	71.5	73%	0.734	40%	0.402	S	S	*	.	H	α-helix	trans	-58.7	-30.7	174.9	-169	178.8	-177.1	0	0	112.5	S45 I46 L47	S45-E49 PolarHBondContact O-N 3.5Å; I46-E49 WeakPolarHBondContact O-CB 3.23Å; I46-E49 PolarHBondContact O-N 3.42Å; L47-E49 PolarHBondContact O-N 3.3Å
50	F	84.7	Confident	87.7	Confident	148 Å²	148	71.8 Å²	71.8	65%	0.649	41%	0.405	S	S	*	.	T	Hydrogen-bonded Turn	trans	-93.1	7.4	175.9	-67.7	-77.9	0	0	0	113.6	I46 L47 E48 I52	I46-F50 HydrophobicContact CG2-CD2 4.45Å; I46-F50 HydrophobicContact CG2-CE2 4.2Å; I46-F50 VanDerWaalsContact O-CD2 3.26Å; I46-F50 WeakPolarHBondContact O-CD2 3.47Å; L47-F50 PolarHBondContact O-N 3.46Å; E48-F50 PolarHBondContact O-N 3.47Å; F50-I52 VanDerWaalsContact C-N 3.26Å; F50-I52 HydrophobicContact CB-CD1 4.12Å; F50-I52 HydrophobicContact CB-CG1 4.35Å; F50-I52 PolarHBondContact O-N 3.45Å
51	G	84.1	Confident	87.6	Confident	73 Å²	73	72 Å²	72	75%	0.753	42%	0.42	S	S	*	.	T	Hydrogen-bonded Turn	trans	70.1	19.7	-178.4	0	0	0	0	0	114	L47 E48	L47-G51 PolarHBondContact O-N 3.47Å; E48-G51 PolarHBondContact O-N 2.91Å
52	I	84.9	Confident	87.5	Confident	79 Å²	79	73.8 Å²	73.8	41%	0.405	42%	0.415	S	S	.	.			trans	-103.9	115.3	-177.1	-60.5	169.4	0	0	0	108.5	L47 F50	L47-I52 CarbonylContact C-O 3.38Å; L47-I52 VanDerWaalsContact C-O 3.24Å; L47-I52 WeakPolarHBondContact CB-O 3.47Å; L47-I52 HydrophobicContact CD2-CG2 4.44Å; L47-I52 PolarHBondContact O-N 3.28Å; L47-I52 VanDerWaalsContact O-O 3.1Å; F50-I52 VanDerWaalsContact C-N 3.26Å; F50-I52 HydrophobicContact CB-CD1 4.12Å; F50-I52 HydrophobicContact CB-CG1 4.35Å; F50-I52 PolarHBondContact O-N 3.45Å
53	G	88.3	Confident	87.5	Confident	53 Å²	53	70.6 Å²	70.6	55%	0.546	40%	0.398	S	S	.	.	P	Polyproline II helix	trans	-66.7	163.2	171.7	0	0	0	0	0	112.2	P55	G53-P55 VanDerWaalsContact O-CD 3.25Å; G53-P55 WeakPolarHBondContact O-CD 3.47Å; G53-P55 VanDerWaalsContact O-N 3.15Å
54	W	90	Very high	87.5	Confident	38 Å²	38	71.5 Å²	71.5	14%	0.144	40%	0.404	C	S	.	.	P	Polyproline II helix	trans	-61.2	118.2	177.4	-169.9	-101.1	0	0	0	110	F12 V39 K40 F44 L47 L58	F12-W54 HydrophobicContact CE1-CZ2 4.2Å; V39-W54 HydrophobicContact CG1-CH2 4.48Å; K40-W54 HydrophobicContact CB-CD2 4.39Å; K40-W54 HydrophobicContact CB-CE3 4.44Å; K40-W54 HydrophobicContact CB-CH2 3.75Å; K40-W54 HydrophobicContact CB-CZ2 3.68Å; K40-W54 HydrophobicContact CB-CZ3 4.13Å; K40-W54 HydrophobicContact CD-CD2 3.97Å; K40-W54 HydrophobicContact CD-CG 4.09Å; K40-W54 HydrophobicContact CD-CZ2 4.38Å; K40-W54 HydrophobicContact CG-CD2 3.75Å; K40-W54 HydrophobicContact CG-CE3 3.9Å; K40-W54 HydrophobicContact CG-CG 4.33Å; K40-W54 HydrophobicContact CG-CH2 4.12Å; K40-W54 HydrophobicContact CG-CZ2 3.98Å; K40-W54 HydrophobicContact CG-CZ3 4.08Å; F44-W54 HydrophobicContact CB-CE3 4.42Å; F44-W54 HydrophobicContact CD2-CB 3.87Å; F44-W54 HydrophobicContact CD2-CE3 4.05Å; F44-W54 HydrophobicContact CE2-CB 3.81Å; L47-W54 HydrophobicContact CD1-CE3 3.58Å; L47-W54 HydrophobicContact CD1-CZ3 3.71Å; W54-L58 HydrophobicContact CZ2-CB 3.8Å; W54-L58 HydrophobicContact CZ2-CD1 4.36Å; W54-L58 VanDerWaalsContact NE1-C 3.3Å; W54-L58 PolarHBondContact NE1-O 2.98Å
55	P	89	Confident	87.2	Confident	45 Å²	45	71.1 Å²	71.1	29%	0.292	41%	0.405	S	S	.	.	P	Polyproline II helix	trans	-63.8	145.2	-170.9	-23.9	33.7	0	0	0	113.2	G53 P57 L58 N59	G53-P55 VanDerWaalsContact O-CD 3.25Å; G53-P55 WeakPolarHBondContact O-CD 3.47Å; G53-P55 VanDerWaalsContact O-N 3.15Å; P55-P57 VanDerWaalsContact C-CD 3.49Å; P55-L58 HydrophobicContact CB-CD1 4.5Å; P55-L58 HydrophobicContact CB-CG 4.4Å; P55-L58 HydrophobicContact CG-CD1 4.17Å; P55-L58 CarbonylContact O-C 3.24Å; P55-L58 PolarHBondContact O-N 2.79Å; P55-N59 PolarHBondContact O-N 2.88Å
56	E	89.1	Confident	86.8	Confident	154 Å²	154	71.6 Å²	71.6	72%	0.72	41%	0.406	S	S	*	.	G	3₁₀ helix	trans	-55.4	-41.8	176.9	-172.1	-176.4	-169.5	0	0	113.7	L58 N59	E56-L58 PolarHBondContact O-N 2.84Å; E56-L58 VanDerWaalsContact O-N 3.15Å; E56-N59 WeakPolarHBondContact O-CB 3.3Å; E56-N59 PolarHBondContact O-N 3.11Å
57	P	86.4	Confident	86	Confident	70 Å²	70	75.8 Å²	75.8	46%	0.455	44%	0.437	S	S	.	.	G	3₁₀ helix	trans	-66.8	-14.2	176.8	-21.2	34.4	0	0	0	114.6	P55	P55-P57 VanDerWaalsContact C-CD 3.49Å
58	L	90.1	Very high	85.8	Confident	15 Å²	15	80.1 Å²	80.1	8%	0.079	46%	0.456	C	S	.	.	G	3₁₀ helix	trans	-103.3	6.7	176.4	-57.6	-177.6	0	0	0	111.5	F12 I13 V16 F17 C36 W54 P55 E56 C60	F12-L58 HydrophobicContact CE1-CB 4.38Å; F12-L58 HydrophobicContact CE1-CD2 3.86Å; F12-L58 HydrophobicContact CE1-CG 4.48Å; F12-L58 HydrophobicContact CZ-CB 4.47Å; F12-L58 HydrophobicContact CZ-CD2 4.14Å; I13-L58 HydrophobicContact CD1-CD1 3.85Å; I13-L58 HydrophobicContact CD1-CD2 3.9Å; V16-L58 HydrophobicContact CB-CD2 4.35Å; V16-L58 HydrophobicContact CG1-CD2 4.08Å; V16-L58 HydrophobicContact CG2-CD2 4.25Å; F17-L58 HydrophobicContact CE2-CD2 4.16Å; C36-L58 PolarHBondContact SG-O 2.92Å; W54-L58 HydrophobicContact CZ2-CB 3.8Å; W54-L58 HydrophobicContact CZ2-CD1 4.36Å; W54-L58 VanDerWaalsContact NE1-C 3.3Å; W54-L58 PolarHBondContact NE1-O 2.98Å; P55-L58 HydrophobicContact CB-CD1 4.5Å; P55-L58 HydrophobicContact CB-CG 4.4Å; P55-L58 HydrophobicContact CG-CD1 4.17Å; P55-L58 CarbonylContact O-C 3.24Å; P55-L58 PolarHBondContact O-N 2.79Å; E56-L58 PolarHBondContact O-N 2.84Å; E56-L58 VanDerWaalsContact O-N 3.15Å; L58-C60 PolarHBondContact O-N 3.48Å; L58-C60 VanDerWaalsContact O-N 3.09Å
59	N	91.4	Very high	85.7	Confident	64 Å²	64	79.1 Å²	79.1	34%	0.342	45%	0.454	S	S	.	.			trans	-61.5	115.4	-176.8	-176.9	-0.3	0	0	0	111.1	P55 E56 A61 Q62	P55-N59 PolarHBondContact O-N 2.88Å; E56-N59 WeakPolarHBondContact O-CB 3.3Å; E56-N59 PolarHBondContact O-N 3.11Å; N59-A61 PolarHBondContact O-N 3.47Å; N59-A61 PolarHBondContact OD1-N 2.95Å; N59-Q62 HydrophobicContact CB-CG 4.33Å; N59-Q62 WeakPolarHBondContact O-CB 3.49Å; N59-Q62 PolarHBondContact O-N 2.87Å
60	C	92.4	Very high	85.9	Confident	7 Å²	7	72.8 Å²	72.8	5%	0.047	43%	0.427	C	S	.	.	G	3₁₀ helix	trans	-61.8	-19.7	-171.7	-56.2	0	0	0	0	114.7	K33 C36 E37 L58 Q62 F63	K33-C60 WeakPolarHBondContact CG-O 3.45Å; C36-C60 HydrophobicContact CB-CB 3.75Å; C36-C60 WeakPolarHBondContact CB-SG 3.44Å; C36-C60 PolarHBondContact O-SG 3.28Å; C36-C60 WeakPolarHBondContact SG-CA 3.43Å; C36-C60 WeakPolarHBondContact SG-CB 3.41Å; C36-C60 CovalentContact SG-SG 2.05Å; C36-C60 PolarHBondContact SG-SG 3.41Å; E37-C60 HydrophobicContact CG-CB 3.96Å; L58-C60 PolarHBondContact O-N 3.48Å; L58-C60 VanDerWaalsContact O-N 3.09Å; C60-Q62 PolarHBondContact O-N 3.28Å; C60-F63 PolarHBondContact O-N 3.33Å
61	A	90	Very high	85.9	Confident	78 Å²	78	67.5 Å²	67.5	65%	0.645	41%	0.405	S	S	*	.	G	3₁₀ helix	trans	-67.8	-15.1	174.7	0	0	0	0	0	114	N59	N59-A61 PolarHBondContact O-N 3.47Å; N59-A61 PolarHBondContact OD1-N 2.95Å
62	Q	88.1	Confident	85.9	Confident	111 Å²	111	69.1 Å²	69.1	52%	0.519	39%	0.391	S	S	.	.	G	3₁₀ helix	trans	-89.7	-8.2	-179.6	-61.7	-179.9	-5.3	0	0	113.3	N59 C60	N59-Q62 HydrophobicContact CB-CG 4.33Å; N59-Q62 WeakPolarHBondContact O-CB 3.49Å; N59-Q62 PolarHBondContact O-N 2.87Å; C60-Q62 PolarHBondContact O-N 3.28Å
63	F	90.3	Very high	85.7	Confident	19 Å²	19	66.4 Å²	66.4	8%	0.083	38%	0.379	C	S	.	.	S	Bend	trans	-95.3	142.7	-178.5	-62.3	-64.8	0	0	0	111.8	F12 V16 T30 S31 K33 C36 C60	F12-F63 HydrophobicContact CE2-CD2 4.32Å; F12-F63 AromaticContact CE2-CE2 3.84Å; F12-F63 HydrophobicContact CE2-CE2 3.84Å; F12-F63 HydrophobicContact CE2-CZ 4.04Å; F12-F63 AromaticContact CZ-CE2 3.81Å; F12-F63 HydrophobicContact CZ-CE2 3.81Å; F12-F63 HydrophobicContact CZ-CZ 4.1Å; V16-F63 HydrophobicContact CB-CZ 4.48Å; V16-F63 HydrophobicContact CG1-CE1 4.43Å; V16-F63 HydrophobicContact CG1-CZ 4.2Å; V16-F63 HydrophobicContact CG2-CE1 3.62Å; V16-F63 HydrophobicContact CG2-CE2 4.49Å; V16-F63 HydrophobicContact CG2-CZ 3.45Å; V16-F63 VanDerWaalsContact CG2-CZ 3.45Å; T30-F63 HydrophobicContact CG2-CD1 3.74Å; T30-F63 HydrophobicContact CG2-CE1 4.24Å; S31-F63 WeakPolarHBondContact O-CB 3.3Å; K33-F63 HydrophobicContact CB-CB 3.99Å; K33-F63 WeakPolarHBondContact CB-O 3.3Å; C36-F63 HydrophobicContact CB-CD2 3.7Å; C36-F63 HydrophobicContact CB-CE2 4.09Å; C60-F63 PolarHBondContact O-N 3.33Å
64	P	88.3	Confident	84.9	Confident	24 Å²	24	68.5 Å²	68.5	16%	0.156	38%	0.381	C	S	.	.			trans	-74.1	157.2	176.8	27	-31.2	0	0	0	112.5	T30 C32 K33 E68 C70	T30-P64 HydrophobicContact CG2-CG 4.4Å; C32-P64 WeakPolarHBondContact CA-O 3.48Å; K33-P64 PolarHBondContact N-O 2.93Å; P64-E68 HydrophobicContact CB-CB 3.78Å; P64-E68 WeakPolarHBondContact CB-OE2 3.38Å; P64-C70 HydrophobicContact CB-CB 4.41Å; P64-C70 HydrophobicContact CG-CB 3.81Å
65	D	83.4	Confident	83.2	Confident	64 Å²	64	75.2 Å²	75.2	34%	0.342	41%	0.414	S	S	.	.			trans	-122	156.5	167.1	-88.3	-38.9	0	0	0	109.7	K33 S34 E68	K33-D65 WeakPolarHBondContact CD-OD2 3.44Å; S34-D65 PolarHBondContact N-OD1 3.23Å; D65-E68 PolarHBondContact O-N 3.36Å; D65-E68 VanDerWaalsContact O-N 3.13Å
66	P	75.9	Confident	81.2	Confident	83 Å²	83	80.3 Å²	80.3	54%	0.539	44%	0.438	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.7	134.7	177.5	-25	34.8	0	0	0	111.4
67	P	68.3	Low	79.2	Confident	140 Å²	140	79.5 Å²	79.5	91%	0.909	44%	0.435	S	S	*	.	T	Hydrogen-bonded Turn	cis	-89.7	-0.6	23.5	34.9	-36.7	0	0	0	116.1
68	E	79.7	Confident	77.2	Confident	132 Å²	132	80.9 Å²	80.9	62%	0.617	44%	0.437	S	S	*	.	S	Bend	trans	-69.3	143	175.3	-67.5	-177.6	179.1	0	0	110.8	P64 D65 C70	P64-E68 HydrophobicContact CB-CB 3.78Å; P64-E68 WeakPolarHBondContact CB-OE2 3.38Å; D65-E68 PolarHBondContact O-N 3.36Å; D65-E68 VanDerWaalsContact O-N 3.13Å; E68-C70 PolarHBondContact O-N 3.1Å
69	L	81.1	Confident	74.5	Confident	108 Å²	108	85.8 Å²	85.8	57%	0.565	47%	0.468	S	S	*	.			trans	-70.7	115.2	-172.5	-170.2	69	0	0	0	110.3	M25 V29	M25-L69 HydrophobicContact CE-CD2 4.01Å; M25-L69 HydrophobicContact SD-CD2 3.74Å; V29-L69 HydrophobicContact CG1-CD2 4.41Å; V29-L69 HydrophobicContact CG1-CG 4.1Å; V29-L69 HydrophobicContact CG2-CD2 3.56Å; V29-L69 HydrophobicContact CG2-CG 4.12Å
70	C	88	Confident	72.2	Confident	23 Å²	23	87.1 Å²	87.1	16%	0.155	50%	0.497	C	S	.	.			trans	-144.1	158.3	-178.6	71.7	0	0	0	0	110.9	C32 P64 E68	C32-C70 VanDerWaalsContact CA-SG 3.57Å; C32-C70 HydrophobicContact CB-CB 3.84Å; C32-C70 WeakPolarHBondContact CB-SG 3.28Å; C32-C70 WeakPolarHBondContact SG-CB 3.5Å; C32-C70 CovalentContact SG-SG 2.02Å; C32-C70 PolarHBondContact SG-SG 3.48Å; P64-C70 HydrophobicContact CB-CB 4.41Å; P64-C70 HydrophobicContact CG-CB 3.81Å; E68-C70 PolarHBondContact O-N 3.1Å
71	M	85.5	Confident	69.3	Low	37 Å²	37	90.2 Å²	90.2	18%	0.182	53%	0.53	C	S	.	.	B	Isolated β-bridge	trans	-100.4	130.7	-174.8	-145	177.3	-78.8	0	0	112.5	F11 M20 V29 T30 S31 C32	F11-M71 HydrophobicContact CE2-CG 4.23Å; F11-M71 HydrophobicContact CE2-SD 4.01Å; F11-M71 HydrophobicContact CZ-CB 3.96Å; F11-M71 HydrophobicContact CZ-CG 3.7Å; F11-M71 HydrophobicContact CZ-SD 3.97Å; M20-M71 HydrophobicContact CB-CE 4.1Å; M20-M71 HydrophobicContact CE-CE 3.27Å; M20-M71 HydrophobicContact CE-SD 3.47Å; M20-M71 WeakPolarHBondContact CE-SD 3.42Å; M20-M71 HydrophobicContact CG-CE 3.72Å; M20-M71 HydrophobicContact SD-CE 3.4Å; M20-M71 WeakPolarHBondContact SD-CE 3.41Å; M20-M71 HydrophobicContact SD-SD 4.41Å; V29-M71 HydrophobicContact CG1-CE 4.36Å; T30-M71 PolarHBondContact O-N 2.84Å; S31-M71 PolarHBondContact OG-O 3.1Å; C32-M71 PolarHBondContact N-O 3.01Å; C32-M71 PolarHBondContact SG-N 3.42Å
72	K	84.4	Confident	66.9	Low	108 Å²	108	96.7 Å²	96.7	47%	0.47	54%	0.544	S	S	.	.			trans	-117.1	148.2	168.9	-59.8	-168.9	179.3	-176.3	0	109.8	C32 S34 V35	C32-K72 HydrophobicContact CB-CG 3.96Å; C32-K72 VanDerWaalsContact SG-CE 3.51Å; C32-K72 WeakPolarHBondContact SG-CG 3.36Å; S34-K72 VanDerWaalsContact OG-CE 3.27Å; S34-K72 WeakPolarHBondContact OG-CE 3.2Å; S34-K72 PolarHBondContact OG-NZ 3.26Å; V35-K72 HydrophobicContact CG2-CB 4.31Å; V35-K72 HydrophobicContact CG2-CG 4.08Å
73	P	79.4	Confident	64.1	Low	22 Å²	22	97 Å²	97	14%	0.143	56%	0.559	C	S	.	*			trans	-65.5	137.5	170.6	25.6	-28.7	0	0	0	109.7	H8 F11	H8-P73 HydrophobicContact CB-CG 4.24Å; H8-P73 VanDerWaalsContact CD2-CG 3.49Å; H8-P73 WeakPolarHBondContact CD2-CG 3.38Å; F11-P73 HydrophobicContact CD1-CB 4.25Å; F11-P73 HydrophobicContact CD1-CG 4.3Å; F11-P73 HydrophobicContact CD2-CB 4.49Å; F11-P73 HydrophobicContact CE1-CB 4.39Å; F11-P73 HydrophobicContact CE1-CG 4.37Å; F11-P73 HydrophobicContact CG-CB 4.3Å
74	T	71.7	Confident	61.5	Low	97 Å²	97	100.7 Å²	100.7	60%	0.595	59%	0.593	S	S	*	*			trans	-73	139.7	172.3	18.4	0	0	0	0	110.2	D76 E77	T74-D76 PolarHBondContact O-N 2.99Å; T74-E77 PolarHBondContact O-N 3.05Å
75	E	53.8	Low	59	Low	178 Å²	178	105.6 Å²	105.6	83%	0.832	62%	0.624	S	S	*	*	G	3₁₀ helix	trans	-58.8	-15.7	-176.2	-65.7	-174.9	164.5	0	0	113.9	E77	E75-E77 VanDerWaalsContact C-N 3.25Å; E75-E77 PolarHBondContact O-N 3.25Å
76	D	47.7	Very low	56.7	Low	152 Å²	152	113.8 Å²	113.8	81%	0.813	65%	0.65	S	S	*	*	G	3₁₀ helix	trans	-74.2	-2.6	178.2	-63.5	-40.5	0	0	0	115	T74	T74-D76 PolarHBondContact O-N 2.99Å
77	E	47.1	Very low	54.6	Low	137 Å²	137	117.5 Å²	117.5	64%	0.64	67%	0.665	S	S	*	*	G	3₁₀ helix	trans	-92.3	1.7	175.2	-71.9	-167.2	145.3	0	0	114.2	T74 E75	T74-E77 PolarHBondContact O-N 3.05Å; E75-E77 VanDerWaalsContact C-N 3.25Å; E75-E77 PolarHBondContact O-N 3.25Å
78	I	45.4	Very low	53.2	Low	100 Å²	100	115.5 Å²	115.5	51%	0.513	65%	0.652	S	S	.	*	S	Bend	trans	-97.3	-17.5	-170.2	-60.7	-178.9	0	0	0	114.7
79	T	32.7	Very low	51.1	Low	118 Å²	118	115 Å²	115	72%	0.724	66%	0.658	S	S	*	*			trans	-141.6	122.9	177.8	47.2	0	0	0	0	113.1	G81	T79-G81 PolarHBondContact O-N 3.5Å
80	G	42.5	Very low	49	Very low	92 Å²	92	119.7 Å²	119.7	95%	0.948	67%	0.674	S	S	*	*			trans	-59.9	119.9	163.5	0	0	0	0	0	110
81	G	31.2	Very low	46.2	Very low	72 Å²	72	122 Å²	122	74%	0.742	70%	0.701	S	S	*	*			trans	162.9	111	173.9	0	0	0	0	0	113.2	T79	T79-G81 PolarHBondContact O-N 3.5Å
82	F	40.9	Very low	43.8	Very low	214 Å²	214	125.6 Å²	125.6	94%	0.939	73%	0.73	S	S	*	*			trans	-55.9	131.2	170.8	-87.5	-104	0	0	0	112.2
83	S	29.8	Very low	41.4	Very low	118 Å²	118	125.3 Å²	125.3	83%	0.825	74%	0.742	S	S	*	*			trans	-175.6	119.6	132.4	-79.8	0	0	0	0	111.4
84	A	35.5	Very low	39.5	Very low	96 Å²	96	129.8 Å²	129.8	79%	0.793	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-88.2	135.8	170.9	0	0	0	0	0	110.9
85	P	34.2	Very low	37.7	Very low	127 Å²	127	131 Å²	131	83%	0.825	79%	0.786	S	S	*	*	P	Polyproline II helix	trans	-78.2	135.3	160	-1.3	18.9	0	0	0	110
86	R	37	Very low	37	Very low	235 Å²	235	127.5 Å²	127.5	89%	0.887	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-76.2	136.8	168.6	-63.4	176.1	-170.4	-125.2	-0.1	109.7
87	L	30.1	Very low	36.7	Very low	162 Å²	162	125.6 Å²	125.6	85%	0.848	78%	0.78	S	S	*	*				177.1	171.2	123.2	-119.4	85	0	0	0	111.6
88	P	40.3	Very low	36.5	Very low	98 Å²	98	127.1 Å²	127.1	64%	0.636	79%	0.785	S	S	*	*				-122.6	162.3	-102.1	41	-24.3	0	0	0	116.3
89	T	36	Very low	36.7	Very low	121 Å²	121	126.5 Å²	126.5	74%	0.742	79%	0.787	S	S	*	*			trans	52.9	115.6	148.7	33.2	0	0	0	0	121.6
90	K	35.3	Very low	37.8	Very low	207 Å²	207	128.1 Å²	128.1	90%	0.9	80%	0.797	S	S	*	*				140.7	131.8	104.9	-98.1	172.2	-179.3	-178.2	0	112.2
91	G	30.7	Very low	38.7	Very low	71 Å²	71	125.8 Å²	125.8	73%	0.732	77%	0.773	S	S	*	*			trans	119.9	92.9	149.7	0	0	0	0	0	117.7
92	S	34	Very low	40.6	Very low	112 Å²	112	123.6 Å²	123.6	78%	0.783	75%	0.746	S	S	*	*			trans	52	127.6	140.5	61.6	0	0	0	0	123.6
93	S	34	Very low	42.1	Very low	102 Å²	102	114.7 Å²	114.7	71%	0.713	71%	0.709	S	S	*	*			trans	75.5	91.9	140.7	58.7	0	0	0	0	121
94	S	39.3	Very low	43.9	Very low	117 Å²	117	114.6 Å²	114.6	82%	0.818	71%	0.709	S	S	*	*				50.3	100.1	124.6	64.1	0	0	0	0	120.4
95	S	34.6	Very low	45.6	Very low	122 Å²	122	113.3 Å²	113.3	85%	0.853	69%	0.688	S	S	*	*				-144.3	111.2	128.8	60.7	0	0	0	0	108.9	S97	S95-S97 PolarHBondContact O-N 3.18Å
96	S	39	Very low	47.8	Very low	104 Å²	104	108 Å²	108	73%	0.727	65%	0.653	S	S	*	*			trans	-55.1	106.6	-175	52	0	0	0	0	113.6	K98	S96-K98 PolarHBondContact O-N 3.45Å
97	S	40.4	Very low	50	Low	113 Å²	113	97.2 Å²	97.2	79%	0.79	61%	0.614	S	S	*	*			trans	-67.9	112.8	152.1	47.1	0	0	0	0	107.5	S95	S95-S97 PolarHBondContact O-N 3.18Å
98	K	44.1	Very low	52.3	Low	169 Å²	169	91.1 Å²	91.1	74%	0.735	58%	0.582	S	S	*	*			trans	-55.5	129.2	170.4	-74.1	178	177.1	177.2	0	107.8	S96 T100	S96-K98 PolarHBondContact O-N 3.45Å; K98-T100 PolarHBondContact O-N 3.01Å; K98-T100 VanDerWaalsContact O-N 3.13Å
99	P	48.6	Very low	54.2	Low	87 Å²	87	88.5 Å²	88.5	57%	0.565	56%	0.564	S	S	*	*			trans	-68	114.8	170.9	26.6	-28.2	0	0	0	107.9	G101 S393	P99-G101 PolarHBondContact O-N 2.92Å; P99-S393 VanDerWaalsContact CD-OG 3.28Å; P99-S393 WeakPolarHBondContact CD-OG 3.15Å
100	T	55.7	Low	56.1	Low	151 Å²	151	86.2 Å²	86.2	93%	0.926	55%	0.547	S	S	*	.			trans	-71.6	16.8	175.7	12.4	0	0	0	0	113.4	K98	K98-T100 PolarHBondContact O-N 3.01Å; K98-T100 VanDerWaalsContact O-N 3.13Å
101	G	62.8	Low	57.6	Low	43 Å²	43	80.1 Å²	80.1	44%	0.443	53%	0.529	S	S	.	.	S	Bend	trans	-127.9	155.3	-176.3	0	0	0	0	0	112.1	P99	P99-G101 PolarHBondContact O-N 2.92Å
102	C	70.7	Confident	59.1	Low	26 Å²	26	85 Å²	85	18%	0.176	53%	0.532	C	S	.	.			trans	-55.8	142.5	170.5	-72.4	0	0	0	0	110.4	L106 D108 C118	C102-L106 HydrophobicContact CB-CB 4.3Å; C102-D108 HydrophobicContact CB-CB 4.07Å; C102-D108 VanDerWaalsContact SG-CA 3.51Å; C102-C118 WeakPolarHBondContact CA-SG 3.23Å; C102-C118 HydrophobicContact CB-CB 3.93Å; C102-C118 WeakPolarHBondContact CB-SG 3.33Å; C102-C118 WeakPolarHBondContact SG-CA 3.38Å; C102-C118 WeakPolarHBondContact SG-CB 3.42Å; C102-C118 CovalentContact SG-SG 2.04Å; C102-C118 PolarHBondContact SG-SG 2.87Å
103	P	71.5	Confident	60.7	Low	27 Å²	27	83.1 Å²	83.1	18%	0.175	51%	0.513	C	S	.	.			trans	-57.8	153	177.6	-17.6	27.6	0	0	0	111.4	D105 L106 K390	P103-D105 PolarHBondContact O-N 3.39Å; P103-L106 HydrophobicContact CG-CD1 4.3Å; P103-L106 PolarHBondContact O-N 3.41Å; P103-K390 HydrophobicContact CB-CB 3.9Å; P103-K390 HydrophobicContact CB-CD 3.36Å; P103-K390 HydrophobicContact CB-CG 4.25Å; P103-K390 HydrophobicContact CG-CB 3.26Å; P103-K390 HydrophobicContact CG-CD 3.55Å; P103-K390 HydrophobicContact CG-CG 4.06Å
104	S	68.7	Low	61.8	Low	117 Å²	117	84.6 Å²	84.6	82%	0.818	52%	0.521	S	S	*	.	T	Hydrogen-bonded Turn	trans	-49.9	-24.6	-173.8	55.9	0	0	0	0	116.1
105	D	70.9	Confident	62.8	Low	68 Å²	68	87.2 Å²	87.2	36%	0.364	52%	0.517	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.6	-0.9	-177.4	-52	-18.5	0	0	0	113.3	P103 K390 R398	P103-D105 PolarHBondContact O-N 3.39Å; D105-K390 VanDerWaalsContact CG-NZ 3.31Å; D105-K390 IonicContact OD2-NZ 3.38Å; D105-K390 PolarHBondContact OD2-NZ 3.32Å; D105-R398 IonicContact OD2-CZ 2.88Å; D105-R398 IonicContact OD2-NH2 2.92Å; D105-R398 PolarHBondContact OD2-NH2 2.94Å
106	L	79.4	Confident	64.3	Low	15 Å²	15	82.8 Å²	82.8	8%	0.079	49%	0.486	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-125.5	157.6	-177.6	-63.2	175.5	0	0	0	110.1	C102 P103 C118 A119 F120 I387	C102-L106 HydrophobicContact CB-CB 4.3Å; P103-L106 HydrophobicContact CG-CD1 4.3Å; P103-L106 PolarHBondContact O-N 3.41Å; L106-C118 HydrophobicContact CB-CB 4.05Å; L106-C118 HydrophobicContact CD1-CB 3.82Å; L106-A119 WeakPolarHBondContact CA-O 3.4Å; L106-F120 HydrophobicContact CD2-CD1 3.47Å; L106-F120 VanDerWaalsContact CD2-CD1 3.47Å; L106-F120 HydrophobicContact CD2-CE1 3.91Å; L106-I387 HydrophobicContact CD1-CG1 4.42Å
107	V	82.9	Confident	65.9	Low	10 Å²	10	84.9 Å²	84.9	6%	0.061	48%	0.484	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-104.9	127.6	177.4	-177	0	0	0	0	108.4	V109 A119 A121	V107-V109 PolarHBondContact O-N 3.48Å; V107-A119 PolarHBondContact N-O 3.13Å; V107-A119 PolarHBondContact O-N 3.08Å; V107-A121 HydrophobicContact CG2-CB 3.79Å
108	D	80.1	Confident	67.7	Low	34 Å²	34	81.6 Å²	81.6	18%	0.182	46%	0.461	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-71.6	117.7	167.1	-169.9	-16.7	0	0	0	109.1	C102 D110 P111 S116	C102-D108 HydrophobicContact CB-CB 4.07Å; C102-D108 VanDerWaalsContact SG-CA 3.51Å; D108-D110 VanDerWaalsContact OD1-C 3.26Å; D108-D110 PolarHBondContact OD1-N 2.86Å; D108-D110 VanDerWaalsContact OD1-N 3.14Å; D108-P111 HydrophobicContact CB-CG 4.48Å; D108-S116 VanDerWaalsContact OD1-CB 3.26Å; D108-S116 WeakPolarHBondContact OD1-CB 3.46Å; D108-S116 PolarHBondContact OD1-OG 2.99Å
109	V	79.9	Confident	69.6	Low	43 Å²	43	73.6 Å²	73.6	26%	0.261	43%	0.426	S	S	.	.	S	Bend	trans	-72.8	-32.7	-175.4	176	0	0	0	0	111.5	V107 H117 A119 Y208	V107-V109 PolarHBondContact O-N 3.48Å; V109-H117 VanDerWaalsContact CG2-O 3.26Å; V109-H117 WeakPolarHBondContact CG2-O 3.35Å; V109-H117 PolarHBondContact N-O 2.95Å; V109-A119 HydrophobicContact CG2-CB 3.43Å; V109-A119 VanDerWaalsContact CG2-CB 3.43Å; V109-Y208 HydrophobicContact CG1-CE1 4.2Å; V109-Y208 HydrophobicContact CG1-CE2 4.03Å; V109-Y208 HydrophobicContact CG2-CD2 3.87Å; V109-Y208 HydrophobicContact CG2-CE2 3.83Å; V109-Y208 HydrophobicContact CG2-CG 4.31Å
110	D	75.6	Confident	71.5	Confident	72 Å²	72	69.9 Å²	69.9	39%	0.385	40%	0.401	S	S	.	.			trans	-142.8	91.9	176.4	-171.9	-6.8	0	0	0	110.3	D108 H112 D113 S116	D108-D110 VanDerWaalsContact OD1-C 3.26Å; D108-D110 PolarHBondContact OD1-N 2.86Å; D108-D110 VanDerWaalsContact OD1-N 3.14Å; D110-H112 PolarHBondContact O-N 3Å; D110-H112 WeakPolarHBondContact OD1-CB 3.4Å; D110-H112 PolarHBondContact OD1-N 2.96Å; D110-D113 HydrophobicContact CB-CB 4.18Å; D110-D113 PolarHBondContact O-N 3.44Å; D110-S116 WeakPolarHBondContact O-CB 3.46Å; D110-S116 PolarHBondContact O-OG 3.42Å
111	P	65.8	Low	73	Confident	79 Å²	79	64.1 Å²	64.1	51%	0.513	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-12.4	178.3	-23.1	33.8	0	0	0	114.5	D108	D108-P111 HydrophobicContact CB-CG 4.48Å
112	H	63.6	Low	74.2	Confident	175 Å²	175	63 Å²	63	81%	0.81	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.5	-12.5	179	-59.3	-55.5	0	0	0	113.2	D110	D110-H112 PolarHBondContact O-N 3Å; D110-H112 WeakPolarHBondContact OD1-CB 3.4Å; D110-H112 PolarHBondContact OD1-N 2.96Å
113	D	67.8	Low	74.9	Confident	71 Å²	71	65.6 Å²	65.6	38%	0.38	36%	0.363	S	S	.	.			trans	-100.8	112.3	172.4	-176.1	2.8	0	0	0	110.1	D110 K115 S116	D110-D113 HydrophobicContact CB-CB 4.18Å; D110-D113 PolarHBondContact O-N 3.44Å; D113-K115 PolarHBondContact O-N 2.91Å; D113-K115 PolarHBondContact OD1-N 3.21Å; D113-S116 WeakPolarHBondContact O-CB 3.46Å; D113-S116 PolarHBondContact O-N 3.45Å; D113-S116 PolarHBondContact O-OG 3.44Å
114	P	57.1	Low	75.6	Confident	134 Å²	134	65.9 Å²	65.9	87%	0.87	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.4	-5.8	176.3	24.1	-31.3	0	0	0	114.3
115	K	60.3	Low	76.5	Confident	172 Å²	172	64.1 Å²	64.1	75%	0.748	35%	0.348	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.1	10.6	170.7	-63.5	-178.8	-178.8	175.6	0	113.3	D113	D113-K115 PolarHBondContact O-N 2.91Å; D113-K115 PolarHBondContact OD1-N 3.21Å
116	S	65.1	Low	77.2	Confident	29 Å²	29	62.1 Å²	62.1	20%	0.203	34%	0.338	C	S	.	.	P	Polyproline II helix	trans	-56.3	144.8	-178.3	68.8	0	0	0	0	112.1	D108 D110 D113	D108-S116 VanDerWaalsContact OD1-CB 3.26Å; D108-S116 WeakPolarHBondContact OD1-CB 3.46Å; D108-S116 PolarHBondContact OD1-OG 2.99Å; D110-S116 WeakPolarHBondContact O-CB 3.46Å; D110-S116 PolarHBondContact O-OG 3.42Å; D113-S116 WeakPolarHBondContact O-CB 3.46Å; D113-S116 PolarHBondContact O-N 3.45Å; D113-S116 PolarHBondContact O-OG 3.44Å
117	H	72.3	Confident	77.6	Confident	148 Å²	148	61.8 Å²	61.8	69%	0.685	34%	0.336	S	S	*	.	P	Polyproline II helix	trans	-85.8	137.3	177.5	-67	-58.7	0	0	0	110.3	V109	V109-H117 VanDerWaalsContact CG2-O 3.26Å; V109-H117 WeakPolarHBondContact CG2-O 3.35Å; V109-H117 PolarHBondContact N-O 2.95Å
118	C	79.4	Confident	78	Confident	44 Å²	44	61.8 Å²	61.8	30%	0.297	34%	0.335	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.5	128.4	169.9	-58.6	0	0	0	0	110.5	C102 L106	C102-C118 WeakPolarHBondContact CA-SG 3.23Å; C102-C118 HydrophobicContact CB-CB 3.93Å; C102-C118 WeakPolarHBondContact CB-SG 3.33Å; C102-C118 WeakPolarHBondContact SG-CA 3.38Å; C102-C118 WeakPolarHBondContact SG-CB 3.42Å; C102-C118 CovalentContact SG-SG 2.04Å; C102-C118 PolarHBondContact SG-SG 2.87Å; L106-C118 HydrophobicContact CB-CB 4.05Å; L106-C118 HydrophobicContact CD1-CB 3.82Å
119	A	84.1	Confident	78.6	Confident	1 Å²	1	62.3 Å²	62.3	1%	0.008	34%	0.341	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.7	160.4	179.6	0	0	0	0	0	111.9	L106 V107 V109 Y208 I211	L106-A119 WeakPolarHBondContact CA-O 3.4Å; V107-A119 PolarHBondContact N-O 3.13Å; V107-A119 PolarHBondContact O-N 3.08Å; V109-A119 HydrophobicContact CG2-CB 3.43Å; V109-A119 VanDerWaalsContact CG2-CB 3.43Å; A119-Y208 HydrophobicContact CB-CD2 3.58Å; A119-Y208 HydrophobicContact CB-CE2 4.47Å; A119-Y208 HydrophobicContact CB-CG 4.09Å; A119-I211 HydrophobicContact CB-CD1 3.58Å
120	F	87.6	Confident	79.3	Confident	8 Å²	8	63.9 Å²	63.9	4%	0.035	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-72.7	136.8	172.8	-66.7	-1.7	0	0	0	110.1	L106 V126 M127 Y208 L209 L299 W382 I387	L106-F120 HydrophobicContact CD2-CD1 3.47Å; L106-F120 VanDerWaalsContact CD2-CD1 3.47Å; L106-F120 HydrophobicContact CD2-CE1 3.91Å; F120-V126 HydrophobicContact CB-CG2 4.36Å; F120-V126 HydrophobicContact CD1-CG1 4.23Å; F120-V126 HydrophobicContact CD2-CB 4.03Å; F120-V126 HydrophobicContact CD2-CG1 4.16Å; F120-V126 HydrophobicContact CD2-CG2 4.22Å; F120-V126 HydrophobicContact CE1-CG1 3.97Å; F120-V126 HydrophobicContact CE2-CB 4.09Å; F120-V126 HydrophobicContact CE2-CG1 3.87Å; F120-V126 HydrophobicContact CG-CB 4.37Å; F120-V126 HydrophobicContact CG-CG1 4.34Å; F120-V126 HydrophobicContact CG-CG2 4.15Å; F120-V126 HydrophobicContact CZ-CG1 3.8Å; F120-M127 HydrophobicContact CE2-CE 3.52Å; F120-M127 HydrophobicContact CE2-CG 4.23Å; F120-M127 HydrophobicContact CZ-CE 3.98Å; F120-Y208 CarbonylContact O-C 3.56Å; F120-Y208 VanDerWaalsContact O-CA 3.26Å; F120-Y208 WeakPolarHBondContact O-CA 3.44Å; F120-Y208 WeakPolarHBondContact O-CB 3.14Å; F120-L209 HydrophobicContact CB-CB 4.31Å; F120-L209 HydrophobicContact CD2-CD2 4.49Å; F120-L209 PolarHBondContact O-N 2.78Å; F120-L299 HydrophobicContact CD2-CD2 4.02Å; F120-L299 HydrophobicContact CE2-CD2 3.59Å; F120-L299 HydrophobicContact CZ-CD2 4.16Å; F120-W382 AromaticContact CE1-CH2 3.77Å; F120-W382 HydrophobicContact CE1-CH2 3.77Å; F120-W382 AromaticContact CE1-CZ3 3.8Å; F120-W382 HydrophobicContact CE1-CZ3 3.8Å; F120-W382 HydrophobicContact CE2-CH2 4.34Å; F120-W382 HydrophobicContact CE2-CZ3 4.47Å; F120-W382 HydrophobicContact CZ-CE3 4.43Å; F120-W382 AromaticContact CZ-CH2 3.39Å; F120-W382 HydrophobicContact CZ-CH2 3.39Å; F120-W382 HydrophobicContact CZ-CZ2 4.49Å; F120-W382 AromaticContact CZ-CZ3 3.35Å; F120-W382 HydrophobicContact CZ-CZ3 3.35Å; F120-I387 HydrophobicContact CE1-CD1 4.12Å
121	A	87.2	Confident	80.1	Confident	31 Å²	31	66 Å²	66	26%	0.256	36%	0.363	S	S	.	.	B	Isolated β-bridge	trans	-60.1	141.1	170.4	0	0	0	0	0	110.4	V107 Q123 S124	V107-A121 HydrophobicContact CG2-CB 3.79Å; A121-Q123 PolarHBondContact O-N 3.06Å; A121-S124 WeakPolarHBondContact O-CB 3.16Å; A121-S124 PolarHBondContact O-N 3.46Å; A121-S124 PolarHBondContact O-OG 3.31Å
122	C	89.1	Confident	81.5	Confident	19 Å²	19	64.1 Å²	64.1	13%	0.128	35%	0.348	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.6	139.5	179.3	-177.5	0	0	0	0	111.2	S124 C199 S207	C122-S124 PolarHBondContact O-N 2.94Å; C122-C199 HydrophobicContact CB-CB 3.68Å; C122-C199 WeakPolarHBondContact CB-SG 3.29Å; C122-C199 WeakPolarHBondContact SG-CB 3.48Å; C122-C199 CovalentContact SG-SG 2.02Å; C122-C199 PolarHBondContact SG-SG 3.47Å; C122-S207 WeakPolarHBondContact CB-OG 3.37Å; C122-S207 PolarHBondContact N-O 3.49Å
123	Q	85.1	Confident	83	Confident	80 Å²	80	56.1 Å²	56.1	37%	0.374	31%	0.311	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.6	5.4	-177.7	-58	-56	-50.2	0	0	116.2	A121 P195	A121-Q123 PolarHBondContact O-N 3.06Å; Q123-P195 HydrophobicContact CG-CG 3.87Å
124	S	85.7	Confident	84.2	Confident	33 Å²	33	61.4 Å²	61.4	23%	0.231	33%	0.326	C	S	.	.			trans	-69.6	150.8	175.9	64.3	0	0	0	0	111.5	A121 C122 V126 K133	A121-S124 WeakPolarHBondContact O-CB 3.16Å; A121-S124 PolarHBondContact O-N 3.46Å; A121-S124 PolarHBondContact O-OG 3.31Å; C122-S124 PolarHBondContact O-N 2.94Å; S124-V126 PolarHBondContact O-N 3.27Å; S124-V126 WeakPolarHBondContact OG-CG2 3.31Å; S124-K133 PolarHBondContact O-NZ 3.44Å
125	N	88.6	Confident	86	Confident	81 Å²	81	58.1 Å²	58.1	43%	0.433	30%	0.3	S	S	.	.			trans	-93.2	79.5	179.2	-69.1	-19.3	0	0	0	109.4	F128 T130 K133	N125-F128 WeakPolarHBondContact CA-O 3.29Å; N125-F128 WeakPolarHBondContact CB-O 3.4Å; N125-F128 PolarHBondContact OD1-O 2.96Å; N125-T130 PolarHBondContact ND2-OG1 3.36Å; N125-K133 PolarHBondContact OD1-NZ 2.91Å
126	V	84.9	Confident	87.6	Confident	25 Å²	25	50 Å²	50	15%	0.152	26%	0.264	C	S	.	.	S	Bend	trans	-93.8	-60.9	-175.1	-175.5	0	0	0	0	110	F120 S124 E289 W382	F120-V126 HydrophobicContact CB-CG2 4.36Å; F120-V126 HydrophobicContact CD1-CG1 4.23Å; F120-V126 HydrophobicContact CD2-CB 4.03Å; F120-V126 HydrophobicContact CD2-CG1 4.16Å; F120-V126 HydrophobicContact CD2-CG2 4.22Å; F120-V126 HydrophobicContact CE1-CG1 3.97Å; F120-V126 HydrophobicContact CE2-CB 4.09Å; F120-V126 HydrophobicContact CE2-CG1 3.87Å; F120-V126 HydrophobicContact CG-CB 4.37Å; F120-V126 HydrophobicContact CG-CG1 4.34Å; F120-V126 HydrophobicContact CG-CG2 4.15Å; F120-V126 HydrophobicContact CZ-CG1 3.8Å; S124-V126 PolarHBondContact O-N 3.27Å; S124-V126 WeakPolarHBondContact OG-CG2 3.31Å; V126-E289 PolarHBondContact N-OE1 2.84Å; V126-E289 VanDerWaalsContact N-OE1 3.09Å; V126-W382 HydrophobicContact CG1-CH2 3.39Å; V126-W382 HydrophobicContact CG1-CZ2 3.57Å
127	M	87.1	Confident	89	Confident	9 Å²	9	50.6 Å²	50.6	4%	0.044	26%	0.262	C	S	.	.	S	Bend	trans	-95.3	-29.6	175.5	-72.5	-161.5	-103.2	0	0	112.5	F120 E289 L299 L379 W382 P402	F120-M127 HydrophobicContact CE2-CE 3.52Å; F120-M127 HydrophobicContact CE2-CG 4.23Å; F120-M127 HydrophobicContact CZ-CE 3.98Å; M127-E289 WeakPolarHBondContact CB-OE2 3.31Å; M127-E289 PolarHBondContact N-OE2 3.27Å; M127-L299 HydrophobicContact CE-CD2 3.37Å; M127-L379 HydrophobicContact CE-CD2 4.01Å; M127-L379 HydrophobicContact SD-CD2 4.12Å; M127-W382 HydrophobicContact CG-CD2 4.35Å; M127-W382 HydrophobicContact CG-CH2 4.35Å; M127-W382 HydrophobicContact CG-CZ2 4Å; M127-P402 HydrophobicContact CB-CG 4.01Å; M127-P402 WeakPolarHBondContact O-CD 3.4Å; M127-P402 WeakPolarHBondContact O-CG 3.38Å
128	F	91.9	Very high	90.1	Very high	9 Å²	9	46.3 Å²	46.3	4%	0.039	25%	0.249	C	C	.	.	S	Bend	trans	-132.9	145.8	-172	-57.6	-76.4	0	0	0	112.4	N125 N132 K133 E289 L290 P402 A404 Y407	N125-F128 WeakPolarHBondContact CA-O 3.29Å; N125-F128 WeakPolarHBondContact CB-O 3.4Å; N125-F128 PolarHBondContact OD1-O 2.96Å; F128-N132 HydrophobicContact CB-CB 4.25Å; F128-K133 HydrophobicContact CB-CG 4.39Å; F128-K133 WeakPolarHBondContact O-CE 3.49Å; F128-K133 PolarHBondContact O-NZ 3.05Å; F128-E289 PolarHBondContact N-OE1 3.49Å; F128-L290 HydrophobicContact CB-CD1 4.11Å; F128-L290 HydrophobicContact CD1-CD1 4.04Å; F128-L290 HydrophobicContact CD2-CB 3.93Å; F128-L290 HydrophobicContact CD2-CD1 4.18Å; F128-L290 HydrophobicContact CE1-CD2 4.35Å; F128-L290 HydrophobicContact CE2-CB 4.02Å; F128-L290 HydrophobicContact CE2-CD2 4.43Å; F128-L290 HydrophobicContact CG-CB 4.46Å; F128-L290 HydrophobicContact CG-CD1 3.84Å; F128-L290 HydrophobicContact CZ-CD2 4.23Å; F128-P402 HydrophobicContact CD1-CG 4.21Å; F128-P402 HydrophobicContact CE1-CB 4.02Å; F128-P402 HydrophobicContact CE1-CG 3.58Å; F128-P402 HydrophobicContact CE2-CG 4.4Å; F128-P402 HydrophobicContact CZ-CB 4.2Å; F128-P402 HydrophobicContact CZ-CG 3.69Å; F128-A404 HydrophobicContact CD1-CB 3.88Å; F128-A404 HydrophobicContact CE1-CB 4.09Å; F128-Y407 HydrophobicContact CE1-CD2 4.35Å; F128-Y407 HydrophobicContact CE1-CG 4.43Å; F128-Y407 AromaticContact CZ-CD1 3.89Å; F128-Y407 HydrophobicContact CZ-CD1 3.89Å; F128-Y407 HydrophobicContact CZ-CD2 4.13Å; F128-Y407 AromaticContact CZ-CE1 3.91Å; F128-Y407 HydrophobicContact CZ-CE1 3.91Å; F128-Y407 HydrophobicContact CZ-CE2 4.17Å; F128-Y407 AromaticContact CZ-CG 4Å; F128-Y407 HydrophobicContact CZ-CG 4Å
129	S	93.4	Very high	90.8	Very high	45 Å²	45	50.3 Å²	50.3	32%	0.315	26%	0.257	S	S	.	.			trans	-72.4	164.1	172.7	69.3	0	0	0	0	111.8	D131 N132 K133	S129-D131 VanDerWaalsContact C-N 3.27Å; S129-D131 PolarHBondContact O-N 3.46Å; S129-N132 PolarHBondContact O-N 3.08Å; S129-N132 PolarHBondContact OG-N 3.12Å; S129-N132 PolarHBondContact OG-ND2 2.99Å; S129-N132 PolarHBondContact OG-OD1 3.36Å; S129-K133 WeakPolarHBondContact O-CG 3.46Å; S129-K133 PolarHBondContact O-N 3.47Å; S129-K133 VanDerWaalsContact O-N 3.1Å
130	T	93.3	Very high	91.4	Very high	76 Å²	76	50.4 Å²	50.4	47%	0.466	26%	0.258	S	S	.	.	H	α-helix	trans	-59.5	-38.4	174.9	-50.2	0	0	0	0	112.1	N125 K133 R134	N125-T130 PolarHBondContact ND2-OG1 3.36Å; T130-K133 PolarHBondContact O-N 3.49Å; T130-R134 PolarHBondContact O-N 3.43Å
131	D	93.9	Very high	91.9	Very high	118 Å²	118	51.6 Å²	51.6	63%	0.631	27%	0.265	S	S	*	.	H	α-helix	trans	-66.5	-42.6	179.2	-62.7	-36.6	0	0	0	111.4	S129 K133 R134 M135	S129-D131 VanDerWaalsContact C-N 3.27Å; S129-D131 PolarHBondContact O-N 3.46Å; D131-K133 VanDerWaalsContact C-N 3.32Å; D131-K133 PolarHBondContact O-N 3.23Å; D131-R134 PolarHBondContact O-N 3.09Å; D131-M135 WeakPolarHBondContact O-CB 3.38Å; D131-M135 PolarHBondContact O-N 2.96Å
132	N	94.8	Very high	92.3	Very high	39 Å²	39	58.7 Å²	58.7	21%	0.209	29%	0.285	C	S	.	.	H	α-helix	trans	-58.8	-45.2	174.5	-69.3	-8.5	0	0	0	110.9	F128 S129 M135 V136 L290 A404	F128-N132 HydrophobicContact CB-CB 4.25Å; S129-N132 PolarHBondContact O-N 3.08Å; S129-N132 PolarHBondContact OG-N 3.12Å; S129-N132 PolarHBondContact OG-ND2 2.99Å; S129-N132 PolarHBondContact OG-OD1 3.36Å; N132-M135 PolarHBondContact O-N 3.08Å; N132-V136 WeakPolarHBondContact O-CG2 3.36Å; N132-V136 PolarHBondContact O-N 2.92Å; N132-L290 HydrophobicContact CB-CD1 4.41Å; N132-A404 HydrophobicContact CB-CB 3.73Å
133	K	94.5	Very high	92.8	Very high	6 Å²	6	60.7 Å²	60.7	3%	0.026	29%	0.292	C	S	.	.	H	α-helix	trans	-61.3	-47	177.3	-66.7	167.3	-167.9	-178.9	0	111.6	S124 N125 F128 S129 T130 D131 R137 E289 L290	S124-K133 PolarHBondContact O-NZ 3.44Å; N125-K133 PolarHBondContact OD1-NZ 2.91Å; F128-K133 HydrophobicContact CB-CG 4.39Å; F128-K133 WeakPolarHBondContact O-CE 3.49Å; F128-K133 PolarHBondContact O-NZ 3.05Å; S129-K133 WeakPolarHBondContact O-CG 3.46Å; S129-K133 PolarHBondContact O-N 3.47Å; S129-K133 VanDerWaalsContact O-N 3.1Å; T130-K133 PolarHBondContact O-N 3.49Å; D131-K133 VanDerWaalsContact C-N 3.32Å; D131-K133 PolarHBondContact O-N 3.23Å; K133-R137 VanDerWaalsContact O-CB 3.29Å; K133-R137 WeakPolarHBondContact O-CB 3.29Å; K133-R137 VanDerWaalsContact O-CD 3.31Å; K133-R137 WeakPolarHBondContact O-CD 3.46Å; K133-R137 WeakPolarHBondContact O-CG 3.33Å; K133-R137 PolarHBondContact O-N 3.39Å; K133-E289 WeakPolarHBondContact CE-OE1 3.38Å; K133-E289 IonicContact NZ-OE1 3.9Å; K133-E289 PolarHBondContact NZ-OE1 3.29Å; K133-L290 HydrophobicContact CG-CD1 4.47Å
134	R	93.4	Very high	93.4	Very high	183 Å²	183	56.9 Å²	56.9	69%	0.691	27%	0.274	S	S	*	.	H	α-helix	trans	-62.2	-46.8	179.5	-178.1	-179.5	-74.2	-168.7	-2.2	111.1	T130 D131 S138	T130-R134 PolarHBondContact O-N 3.43Å; D131-R134 PolarHBondContact O-N 3.09Å; R134-S138 VanDerWaalsContact O-CB 3.3Å; R134-S138 WeakPolarHBondContact O-CB 3.41Å; R134-S138 PolarHBondContact O-N 3.36Å
135	M	93.9	Very high	93.9	Very high	65 Å²	65	57.6 Å²	57.6	32%	0.32	28%	0.282	S	S	.	.	H	α-helix	trans	-58.6	-55.2	179.1	-177.9	176	69.3	0	0	110.9	D131 N132 R137 S138 W139 M408	D131-M135 WeakPolarHBondContact O-CB 3.38Å; D131-M135 PolarHBondContact O-N 2.96Å; N132-M135 PolarHBondContact O-N 3.08Å; M135-R137 PolarHBondContact O-N 3.47Å; M135-S138 PolarHBondContact O-N 3.36Å; M135-W139 VanDerWaalsContact O-CD1 3.26Å; M135-W139 PolarHBondContact O-N 2.69Å; M135-M408 HydrophobicContact CE-SD 4.07Å; M135-M408 HydrophobicContact CG-SD 4.2Å; M135-M408 HydrophobicContact SD-SD 4.5Å
136	V	95.3	Very high	94.3	Very high	0 Å²	0	55.8 Å²	55.8	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-63.8	-43.3	-176.2	175.8	0	0	0	0	111.8	N132 S138 S140 L290 T291 M408	N132-V136 WeakPolarHBondContact O-CG2 3.36Å; N132-V136 PolarHBondContact O-N 2.92Å; V136-S138 PolarHBondContact O-N 3.35Å; V136-S140 VanDerWaalsContact O-CB 3.25Å; V136-S140 WeakPolarHBondContact O-CB 3.44Å; V136-S140 PolarHBondContact O-N 2.95Å; V136-S140 PolarHBondContact O-OG 2.96Å; V136-L290 HydrophobicContact CB-CD1 4.04Å; V136-L290 HydrophobicContact CB-CD2 4.39Å; V136-L290 HydrophobicContact CB-CG 4Å; V136-L290 HydrophobicContact CG1-CD2 4.08Å; V136-L290 HydrophobicContact CG1-CG 3.91Å; V136-L290 HydrophobicContact CG2-CD1 3.85Å; V136-L290 HydrophobicContact CG2-CD2 4.08Å; V136-L290 HydrophobicContact CG2-CG 4.06Å; V136-T291 HydrophobicContact CG1-CG2 4.15Å; V136-M408 HydrophobicContact CG2-CB 3.77Å; V136-M408 HydrophobicContact CG2-CG 3.97Å; V136-M408 HydrophobicContact CG2-SD 4.01Å
137	R	94.2	Very high	94.9	Very high	43 Å²	43	54.6 Å²	54.6	16%	0.162	27%	0.271	C	S	.	.	H	α-helix	trans	-62.3	-43.8	178.1	-68.2	167.5	-169.7	177.8	0.4	111.4	K133 M135 S140 I141 E289 L290	K133-R137 VanDerWaalsContact O-CB 3.29Å; K133-R137 WeakPolarHBondContact O-CB 3.29Å; K133-R137 VanDerWaalsContact O-CD 3.31Å; K133-R137 WeakPolarHBondContact O-CD 3.46Å; K133-R137 WeakPolarHBondContact O-CG 3.33Å; K133-R137 PolarHBondContact O-N 3.39Å; M135-R137 PolarHBondContact O-N 3.47Å; R137-S140 PolarHBondContact O-N 2.88Å; R137-I141 WeakPolarHBondContact O-CD1 3.23Å; R137-I141 VanDerWaalsContact O-CG1 3.31Å; R137-I141 WeakPolarHBondContact O-CG1 3.44Å; R137-I141 PolarHBondContact O-N 2.95Å; R137-E289 PolarHBondContact NH2-O 3Å; R137-L290 PolarHBondContact NE-O 3.44Å
138	S	94	Very high	95.4	Very high	58 Å²	58	54.5 Å²	54.5	41%	0.406	27%	0.271	S	S	.	.	H	α-helix	trans	-64.1	-49.1	179.1	-177.9	0	0	0	0	112.4	R134 M135 V136 S140 I141 W142	R134-S138 VanDerWaalsContact O-CB 3.3Å; R134-S138 WeakPolarHBondContact O-CB 3.41Å; R134-S138 PolarHBondContact O-N 3.36Å; M135-S138 PolarHBondContact O-N 3.36Å; V136-S138 PolarHBondContact O-N 3.35Å; S138-S140 PolarHBondContact O-N 3.23Å; S138-I141 WeakPolarHBondContact O-CB 3.49Å; S138-I141 PolarHBondContact O-N 3.38Å; S138-W142 PolarHBondContact O-N 2.92Å
139	W	96.1	Very high	95.7	Very high	127 Å²	127	56 Å²	56	48%	0.481	29%	0.289	S	S	.	.	H	α-helix	trans	-65.5	-38.3	178.5	-80.7	106	0	0	0	112.8	M135 I141 W142 F143 M408	M135-W139 VanDerWaalsContact O-CD1 3.26Å; M135-W139 PolarHBondContact O-N 2.69Å; W139-I141 PolarHBondContact O-N 3.36Å; W139-W142 PolarHBondContact O-N 2.9Å; W139-F143 HydrophobicContact CE3-CD2 4.14Å; W139-F143 AromaticContact CE3-CE2 3.59Å; W139-F143 HydrophobicContact CE3-CE2 3.59Å; W139-F143 HydrophobicContact CZ3-CE2 4.01Å; W139-F143 WeakPolarHBondContact O-CD2 3.5Å; W139-F143 PolarHBondContact O-N 3.48Å; W139-F143 VanDerWaalsContact O-N 3.1Å; W139-M408 HydrophobicContact CB-CE 3.48Å; W139-M408 VanDerWaalsContact CB-CE 3.48Å; W139-M408 HydrophobicContact CB-SD 4.49Å; W139-M408 HydrophobicContact CD2-CE 3.89Å; W139-M408 HydrophobicContact CG-CE 3.28Å
140	S	96.4	Very high	95.8	Very high	4 Å²	4	54.8 Å²	54.8	3%	0.028	28%	0.28	C	S	.	.	H	α-helix	trans	-58	-37.2	177.2	-59.3	0	0	0	0	111.8	V136 R137 S138 A144 V411	V136-S140 VanDerWaalsContact O-CB 3.25Å; V136-S140 WeakPolarHBondContact O-CB 3.44Å; V136-S140 PolarHBondContact O-N 2.95Å; V136-S140 PolarHBondContact O-OG 2.96Å; R137-S140 PolarHBondContact O-N 2.88Å; S138-S140 PolarHBondContact O-N 3.23Å; S140-A144 WeakPolarHBondContact O-CB 3.5Å; S140-A144 PolarHBondContact O-N 3.46Å; S140-V411 WeakPolarHBondContact OG-CG1 3.47Å
141	I	96.9	Very high	95.9	Very high	33 Å²	33	51.1 Å²	51.1	17%	0.169	26%	0.257	C	S	.	.	H	α-helix	trans	-63.1	-49	177.1	-65.8	161.7	0	0	0	110.9	R137 S138 W139 A144 A145 L187 P189 L190	R137-I141 WeakPolarHBondContact O-CD1 3.23Å; R137-I141 VanDerWaalsContact O-CG1 3.31Å; R137-I141 WeakPolarHBondContact O-CG1 3.44Å; R137-I141 PolarHBondContact O-N 2.95Å; S138-I141 WeakPolarHBondContact O-CB 3.49Å; S138-I141 PolarHBondContact O-N 3.38Å; W139-I141 PolarHBondContact O-N 3.36Å; I141-A144 PolarHBondContact O-N 2.87Å; I141-A145 WeakPolarHBondContact O-CB 3.39Å; I141-A145 PolarHBondContact O-N 3.17Å; I141-L187 HydrophobicContact CG2-CD2 4.4Å; I141-P189 HydrophobicContact CD1-CB 3.97Å; I141-P189 HydrophobicContact CG1-CB 4.38Å; I141-P189 HydrophobicContact CG1-CG 4.41Å; I141-L190 HydrophobicContact CD1-CD2 4.35Å; I141-L190 HydrophobicContact CG2-CD1 4.17Å; I141-L190 HydrophobicContact CG2-CD2 3.84Å; I141-L190 HydrophobicContact CG2-CG 4.05Å
142	W	96.9	Very high	96	Very high	180 Å²	180	48.6 Å²	48.6	68%	0.682	24%	0.243	S	C	*	.	H	α-helix	trans	-60	-49.1	-179.4	-74.2	112	0	0	0	112.1	S138 W139 A145 A146	S138-W142 PolarHBondContact O-N 2.92Å; W139-W142 PolarHBondContact O-N 2.9Å; W142-A145 PolarHBondContact O-N 2.91Å; W142-A146 PolarHBondContact O-N 3.06Å; W142-A146 VanDerWaalsContact O-N 3.13Å
143	F	97.8	Very high	96	Very high	61 Å²	61	50.3 Å²	50.3	27%	0.268	25%	0.249	S	C	.	.	H	α-helix	trans	-66.7	-39	178.2	-80.1	-80.4	0	0	0	112	W139 A146 N147 I412 L415	W139-F143 HydrophobicContact CE3-CD2 4.14Å; W139-F143 AromaticContact CE3-CE2 3.59Å; W139-F143 HydrophobicContact CE3-CE2 3.59Å; W139-F143 HydrophobicContact CZ3-CE2 4.01Å; W139-F143 WeakPolarHBondContact O-CD2 3.5Å; W139-F143 PolarHBondContact O-N 3.48Å; W139-F143 VanDerWaalsContact O-N 3.1Å; F143-A146 PolarHBondContact O-N 2.86Å; F143-N147 VanDerWaalsContact O-CB 3.23Å; F143-N147 WeakPolarHBondContact O-CB 3.21Å; F143-N147 PolarHBondContact O-N 3.31Å; F143-I412 HydrophobicContact CD1-CG2 3.88Å; F143-I412 HydrophobicContact CD2-CD1 3.93Å; F143-I412 HydrophobicContact CD2-CG1 3.76Å; F143-I412 HydrophobicContact CD2-CG2 4.19Å; F143-I412 HydrophobicContact CE1-CG2 3.73Å; F143-I412 HydrophobicContact CE2-CD1 3.65Å; F143-I412 HydrophobicContact CE2-CG1 3.96Å; F143-I412 HydrophobicContact CE2-CG2 4.05Å; F143-I412 HydrophobicContact CG-CG1 4.22Å; F143-I412 HydrophobicContact CG-CG2 4.11Å; F143-I412 HydrophobicContact CZ-CD1 4.3Å; F143-I412 HydrophobicContact CZ-CG2 3.82Å; F143-L415 HydrophobicContact CB-CB 4.1Å; F143-L415 HydrophobicContact CB-CD1 3.98Å
144	A	98	Very high	96	Very high	0 Å²	0	50 Å²	50	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-66.5	-38.4	177.6	0	0	0	0	0	112.2	S140 I141 N147 A148 Y186 L187 L415	S140-A144 WeakPolarHBondContact O-CB 3.5Å; S140-A144 PolarHBondContact O-N 3.46Å; I141-A144 PolarHBondContact O-N 2.87Å; A144-N147 PolarHBondContact O-N 2.81Å; A144-A148 WeakPolarHBondContact O-CB 3.41Å; A144-A148 PolarHBondContact O-N 3.03Å; A144-Y186 HydrophobicContact CB-CG 4.47Å; A144-L187 HydrophobicContact CB-CD2 3.84Å; A144-L187 HydrophobicContact CB-CG 4.16Å; A144-L415 HydrophobicContact CB-CD1 4.01Å; A144-L415 HydrophobicContact CB-CD2 4.08Å
145	A	97.8	Very high	96	Very high	48 Å²	48	43.4 Å²	43.4	40%	0.397	22%	0.224	S	C	.	.	H	α-helix	trans	-65.1	-45.4	177.4	0	0	0	0	0	111	I141 W142 G149 L187	I141-A145 WeakPolarHBondContact O-CB 3.39Å; I141-A145 PolarHBondContact O-N 3.17Å; W142-A145 PolarHBondContact O-N 2.91Å; A145-G149 PolarHBondContact O-N 3.45Å; A145-L187 HydrophobicContact CB-CD2 4.03Å
146	A	97.1	Very high	95.9	Very high	42 Å²	42	43.5 Å²	43.5	35%	0.347	23%	0.226	S	C	.	.	H	α-helix	trans	-61.7	-48	175.3	0	0	0	0	0	111.6	W142 F143 G149 V150 F419	W142-A146 PolarHBondContact O-N 3.06Å; W142-A146 VanDerWaalsContact O-N 3.13Å; F143-A146 PolarHBondContact O-N 2.86Å; A146-G149 PolarHBondContact O-N 3.41Å; A146-V150 WeakPolarHBondContact O-CB 3.47Å; A146-V150 VanDerWaalsContact O-CG2 3.31Å; A146-V150 WeakPolarHBondContact O-CG2 3.34Å; A146-V150 PolarHBondContact O-N 3.24Å; A146-F419 HydrophobicContact CB-CZ 3.94Å
147	N	97.1	Very high	95.7	Very high	1 Å²	1	43.8 Å²	43.8	1%	0.005	23%	0.227	C	C	.	.	H	α-helix	trans	-62.1	-46.9	179.7	-167.5	51.3	0	0	0	112.3	F143 A144 V150 A151 I179 S183 L415 G418	F143-N147 VanDerWaalsContact O-CB 3.23Å; F143-N147 WeakPolarHBondContact O-CB 3.21Å; F143-N147 PolarHBondContact O-N 3.31Å; A144-N147 PolarHBondContact O-N 2.81Å; N147-V150 PolarHBondContact O-N 2.98Å; N147-A151 WeakPolarHBondContact O-CB 3.32Å; N147-A151 PolarHBondContact O-N 2.63Å; N147-I179 WeakPolarHBondContact ND2-CG2 3.42Å; N147-S183 PolarHBondContact ND2-OG 3.4Å; N147-L415 HydrophobicContact CB-CB 4.47Å; N147-L415 WeakPolarHBondContact CB-O 3.33Å; N147-L415 PolarHBondContact OD1-O 3.28Å; N147-G418 WeakPolarHBondContact OD1-CA 3.49Å; N147-G418 PolarHBondContact OD1-N 3Å
148	A	97.6	Very high	95.4	Very high	6 Å²	6	41.9 Å²	41.9	5%	0.05	22%	0.22	C	C	.	.	H	α-helix	trans	-63.1	-43.6	177.8	0	0	0	0	0	111.3	A144 A151 L152 F180 L187	A144-A148 WeakPolarHBondContact O-CB 3.41Å; A144-A148 PolarHBondContact O-N 3.03Å; A148-A151 PolarHBondContact O-N 3.27Å; A148-L152 WeakPolarHBondContact O-CB 3.45Å; A148-L152 PolarHBondContact O-N 3.4Å; A148-F180 HydrophobicContact CB-CD2 3.99Å; A148-F180 HydrophobicContact CB-CE2 4.3Å; A148-L187 HydrophobicContact CB-CD1 4.35Å
149	G	96.7	Very high	95.2	Very high	40 Å²	40	41 Å²	41	41%	0.412	22%	0.217	S	C	.	.	H	α-helix	trans	-60.4	-47.3	177	0	0	0	0	0	112.3	A145 A146 F153	A145-G149 PolarHBondContact O-N 3.45Å; A146-G149 PolarHBondContact O-N 3.41Å; G149-F153 VanDerWaalsContact O-CB 3.3Å; G149-F153 WeakPolarHBondContact O-CB 3.3Å; G149-F153 PolarHBondContact O-N 3.01Å
150	V	95.7	Very high	94.8	Very high	20 Å²	20	37.8 Å²	37.8	12%	0.121	21%	0.208	C	C	.	.	H	α-helix	trans	-62.5	-47.6	176.6	165.9	0	0	0	0	111.9	A146 N147 F153 S154 G418 F419 L422	A146-V150 WeakPolarHBondContact O-CB 3.47Å; A146-V150 VanDerWaalsContact O-CG2 3.31Å; A146-V150 WeakPolarHBondContact O-CG2 3.34Å; A146-V150 PolarHBondContact O-N 3.24Å; N147-V150 PolarHBondContact O-N 2.98Å; V150-F153 PolarHBondContact O-N 2.92Å; V150-S154 WeakPolarHBondContact O-CB 3.42Å; V150-S154 PolarHBondContact O-N 3.2Å; V150-S154 PolarHBondContact O-OG 3.16Å; V150-G418 WeakPolarHBondContact CG1-O 3.47Å; V150-F419 HydrophobicContact CG2-CD1 4.18Å; V150-F419 HydrophobicContact CG2-CE1 4.1Å; V150-L422 HydrophobicContact CB-CD2 4.36Å; V150-L422 HydrophobicContact CB-CG 4.46Å; V150-L422 HydrophobicContact CG1-CD1 4.2Å; V150-L422 HydrophobicContact CG1-CD2 3.68Å; V150-L422 HydrophobicContact CG1-CG 3.49Å; V150-L422 VanDerWaalsContact CG1-CG 3.49Å; V150-L422 HydrophobicContact CG2-CD1 4.11Å; V150-L422 HydrophobicContact CG2-CD2 4.01Å; V150-L422 HydrophobicContact CG2-CG 4.16Å
151	A	96.5	Very high	94	Very high	0 Å²	0	40 Å²	40	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-66.5	-41.4	-177.9	0	0	0	0	0	111.5	N147 A148 S154 F155 I179 F180	N147-A151 WeakPolarHBondContact O-CB 3.32Å; N147-A151 PolarHBondContact O-N 2.63Å; A148-A151 PolarHBondContact O-N 3.27Å; A151-S154 WeakPolarHBondContact O-CB 3.48Å; A151-S154 PolarHBondContact O-N 3.48Å; A151-F155 WeakPolarHBondContact O-CB 3.33Å; A151-F155 PolarHBondContact O-N 2.94Å; A151-I179 HydrophobicContact CB-CB 4.23Å; A151-I179 HydrophobicContact CB-CG2 3.94Å; A151-F180 HydrophobicContact CB-CB 3.89Å
152	L	96.1	Very high	93.2	Very high	64 Å²	64	47.5 Å²	47.5	34%	0.335	25%	0.246	S	C	.	.	H	α-helix	trans	-64.5	-48.3	175.6	-179.3	61	0	0	0	111.4	A148 S154 F155 L156 F180	A148-L152 WeakPolarHBondContact O-CB 3.45Å; A148-L152 PolarHBondContact O-N 3.4Å; L152-S154 PolarHBondContact O-N 3.22Å; L152-F155 PolarHBondContact O-N 3.22Å; L152-L156 HydrophobicContact CD1-CD1 4.11Å; L152-L156 HydrophobicContact CD1-CG 4.07Å; L152-L156 HydrophobicContact CG-CD1 3.97Å; L152-L156 HydrophobicContact CG-CG 4.35Å; L152-L156 WeakPolarHBondContact O-CB 3.39Å; L152-L156 VanDerWaalsContact O-CG 3.29Å; L152-L156 WeakPolarHBondContact O-CG 3.49Å; L152-L156 PolarHBondContact O-N 3.45Å; L152-F180 HydrophobicContact CB-CD2 3.81Å; L152-F180 HydrophobicContact CB-CE2 4.03Å; L152-F180 HydrophobicContact CB-CG 4.41Å; L152-F180 HydrophobicContact CD1-CE1 4.45Å; L152-F180 HydrophobicContact CD1-CE2 4.34Å; L152-F180 HydrophobicContact CD1-CZ 4.3Å; L152-F180 HydrophobicContact CD2-CE2 4.11Å; L152-F180 HydrophobicContact CD2-CZ 4.46Å; L152-F180 HydrophobicContact CG-CE2 4.39Å
153	F	94.2	Very high	92.3	Very high	75 Å²	75	48.4 Å²	48.4	33%	0.329	26%	0.255	S	S	.	.	H	α-helix	trans	-58.2	-39.8	175.8	176.8	-105.4	0	0	0	111.5	G149 V150 T157 V425 T430 W434	G149-F153 VanDerWaalsContact O-CB 3.3Å; G149-F153 WeakPolarHBondContact O-CB 3.3Å; G149-F153 PolarHBondContact O-N 3.01Å; V150-F153 PolarHBondContact O-N 2.92Å; F153-T157 WeakPolarHBondContact O-CB 3.22Å; F153-T157 PolarHBondContact O-N 2.85Å; F153-T157 PolarHBondContact O-OG1 3.47Å; F153-V425 HydrophobicContact CD1-CB 4.39Å; F153-V425 HydrophobicContact CD1-CG2 3.79Å; F153-V425 HydrophobicContact CE1-CB 3.98Å; F153-V425 HydrophobicContact CE1-CG2 3.71Å; F153-T430 HydrophobicContact CZ-CG2 4.05Å; F153-W434 HydrophobicContact CD2-CH2 4.37Å; F153-W434 AromaticContact CD2-CZ2 3.69Å; F153-W434 HydrophobicContact CD2-CZ2 3.69Å; F153-W434 HydrophobicContact CE2-CD2 4.25Å; F153-W434 AromaticContact CE2-CE2 3.48Å; F153-W434 VanDerWaalsContact CE2-CE2 3.48Å; F153-W434 HydrophobicContact CE2-CH2 4.42Å; F153-W434 AromaticContact CE2-CZ2 3.58Å; F153-W434 HydrophobicContact CE2-CZ2 3.58Å; F153-W434 AromaticContact CE2-NE1 3.46Å; F153-W434 AromaticContact CZ-NE1 3.75Å
154	S	93.4	Very high	91.4	Very high	0 Å²	0	49.3 Å²	49.3	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-62.4	-53.3	176.2	-59.2	0	0	0	0	111.2	V150 A151 L152 L156 T157 F158 C421	V150-S154 WeakPolarHBondContact O-CB 3.42Å; V150-S154 PolarHBondContact O-N 3.2Å; V150-S154 PolarHBondContact O-OG 3.16Å; A151-S154 WeakPolarHBondContact O-CB 3.48Å; A151-S154 PolarHBondContact O-N 3.48Å; L152-S154 PolarHBondContact O-N 3.22Å; S154-L156 PolarHBondContact O-N 3.45Å; S154-T157 WeakPolarHBondContact O-CB 3.04Å; S154-T157 PolarHBondContact O-N 3.31Å; S154-F158 WeakPolarHBondContact O-CD2 3.36Å; S154-F158 PolarHBondContact O-N 3Å; S154-C421 WeakPolarHBondContact OG-CB 3.44Å
155	F	94.4	Very high	90.5	Very high	44 Å²	44	49.9 Å²	49.9	19%	0.193	26%	0.259	C	S	.	.	H	α-helix	trans	-55.6	-47.9	177.9	174.3	-99.9	0	0	0	112.4	A151 L152 T157 F158 A159 F173 S176 L177	A151-F155 WeakPolarHBondContact O-CB 3.33Å; A151-F155 PolarHBondContact O-N 2.94Å; L152-F155 PolarHBondContact O-N 3.22Å; F155-T157 PolarHBondContact O-N 3.35Å; F155-F158 PolarHBondContact O-N 3.02Å; F155-A159 WeakPolarHBondContact O-CB 3.37Å; F155-A159 PolarHBondContact O-N 3.17Å; F155-F173 AromaticContact CD2-CD2 3.75Å; F155-F173 HydrophobicContact CD2-CD2 3.75Å; F155-F173 AromaticContact CD2-CE2 3.37Å; F155-F173 HydrophobicContact CD2-CE2 3.37Å; F155-F173 AromaticContact CD2-CZ 3.95Å; F155-F173 HydrophobicContact CD2-CZ 3.95Å; F155-F173 AromaticContact CE2-CD2 3.97Å; F155-F173 HydrophobicContact CE2-CD2 3.97Å; F155-F173 HydrophobicContact CE2-CE1 4.13Å; F155-F173 AromaticContact CE2-CE2 3.17Å; F155-F173 HydrophobicContact CE2-CE2 3.17Å; F155-F173 AromaticContact CE2-CZ 3.28Å; F155-F173 HydrophobicContact CE2-CZ 3.28Å; F155-F173 HydrophobicContact CG-CE2 4.27Å; F155-F173 AromaticContact CZ-CE2 3.94Å; F155-F173 HydrophobicContact CZ-CE2 3.94Å; F155-F173 AromaticContact CZ-CZ 3.93Å; F155-F173 HydrophobicContact CZ-CZ 3.93Å; F155-S176 WeakPolarHBondContact CA-OG 3.46Å; F155-S176 WeakPolarHBondContact CB-OG 3.08Å; F155-S176 PolarHBondContact N-OG 3.04Å; F155-L177 HydrophobicContact CD2-CB 3.74Å; F155-L177 HydrophobicContact CD2-CD1 4.19Å; F155-L177 HydrophobicContact CD2-CG 4.42Å; F155-L177 HydrophobicContact CE1-CD1 4.48Å; F155-L177 HydrophobicContact CE2-CB 3.88Å; F155-L177 HydrophobicContact CE2-CD1 3.93Å; F155-L177 HydrophobicContact CE2-CD2 4.01Å; F155-L177 HydrophobicContact CE2-CG 4.16Å; F155-L177 HydrophobicContact CZ-CD1 4.1Å
156	L	92.5	Very high	89.7	Confident	67 Å²	67	53.6 Å²	53.6	35%	0.351	26%	0.263	S	S	.	.	H	α-helix	trans	-63	-41.9	178.9	-69.7	175.8	0	0	0	111.8	L152 S154 F158 A159 I160 W434	L152-L156 HydrophobicContact CD1-CD1 4.11Å; L152-L156 HydrophobicContact CD1-CG 4.07Å; L152-L156 HydrophobicContact CG-CD1 3.97Å; L152-L156 HydrophobicContact CG-CG 4.35Å; L152-L156 WeakPolarHBondContact O-CB 3.39Å; L152-L156 VanDerWaalsContact O-CG 3.29Å; L152-L156 WeakPolarHBondContact O-CG 3.49Å; L152-L156 PolarHBondContact O-N 3.45Å; S154-L156 PolarHBondContact O-N 3.45Å; L156-F158 VanDerWaalsContact C-N 3.34Å; L156-F158 PolarHBondContact O-N 2.9Å; L156-A159 WeakPolarHBondContact O-CB 3.36Å; L156-A159 PolarHBondContact O-N 3.17Å; L156-A159 VanDerWaalsContact O-N 3.13Å; L156-I160 VanDerWaalsContact O-CG1 3.32Å; L156-I160 WeakPolarHBondContact O-CG1 3.3Å; L156-I160 PolarHBondContact O-N 2.76Å; L156-W434 HydrophobicContact CB-CH2 4.11Å; L156-W434 HydrophobicContact CB-CZ2 3.95Å; L156-W434 HydrophobicContact CD1-CH2 4.23Å
157	T	90.4	Very high	89.1	Confident	6 Å²	6	51.9 Å²	51.9	4%	0.037	25%	0.247	C	C	.	.	H	α-helix	trans	-59.8	-44.8	176.3	-62.6	0	0	0	0	111.6	F153 S154 F155 A159 I160 D161 V425 T430 W434	F153-T157 WeakPolarHBondContact O-CB 3.22Å; F153-T157 PolarHBondContact O-N 2.85Å; F153-T157 PolarHBondContact O-OG1 3.47Å; S154-T157 WeakPolarHBondContact O-CB 3.04Å; S154-T157 PolarHBondContact O-N 3.31Å; F155-T157 PolarHBondContact O-N 3.35Å; T157-A159 VanDerWaalsContact C-N 3.34Å; T157-I160 PolarHBondContact O-N 2.65Å; T157-D161 PolarHBondContact O-N 3.09Å; T157-V425 HydrophobicContact CG2-CB 4.06Å; T157-V425 HydrophobicContact CG2-CG1 3.63Å; T157-T430 HydrophobicContact CG2-CG2 3.55Å; T157-W434 PolarHBondContact OG1-NE1 3.38Å
158	F	88.8	Confident	88.4	Confident	3 Å²	3	52.3 Å²	52.3	1%	0.013	25%	0.25	C	S	.	.	H	α-helix	trans	-65.7	-36.3	174.9	-78.4	-70.2	0	0	0	112.3	S154 F155 L156 D161 R162 F165 V172 F173 W424 V425	S154-F158 WeakPolarHBondContact O-CD2 3.36Å; S154-F158 PolarHBondContact O-N 3Å; F155-F158 PolarHBondContact O-N 3.02Å; L156-F158 VanDerWaalsContact C-N 3.34Å; L156-F158 PolarHBondContact O-N 2.9Å; F158-D161 CarbonylContact O-C 3.55Å; F158-D161 PolarHBondContact O-N 3.43Å; F158-R162 WeakPolarHBondContact O-CA 3.44Å; F158-R162 WeakPolarHBondContact O-CG 3.44Å; F158-R162 PolarHBondContact O-N 3.17Å; F158-F165 HydrophobicContact CD1-CB 4.05Å; F158-F165 AromaticContact CD1-CD1 3.89Å; F158-F165 HydrophobicContact CD1-CD1 3.89Å; F158-F165 AromaticContact CD1-CD2 3.35Å; F158-F165 HydrophobicContact CD1-CD2 3.35Å; F158-F165 HydrophobicContact CD1-CE1 4.1Å; F158-F165 AromaticContact CD1-CE2 3.59Å; F158-F165 HydrophobicContact CD1-CE2 3.59Å; F158-F165 AromaticContact CD1-CG 3.49Å; F158-F165 HydrophobicContact CD1-CG 3.49Å; F158-F165 VanDerWaalsContact CD1-CG 3.49Å; F158-F165 AromaticContact CD1-CZ 3.95Å; F158-F165 HydrophobicContact CD1-CZ 3.95Å; F158-F165 HydrophobicContact CE1-CB 4.11Å; F158-F165 AromaticContact CE1-CD1 3.45Å; F158-F165 HydrophobicContact CE1-CD1 3.45Å; F158-F165 VanDerWaalsContact CE1-CD1 3.45Å; F158-F165 AromaticContact CE1-CD2 3.85Å; F158-F165 HydrophobicContact CE1-CD2 3.85Å; F158-F165 AromaticContact CE1-CE1 3.66Å; F158-F165 HydrophobicContact CE1-CE1 3.66Å; F158-F165 HydrophobicContact CE1-CE2 4.04Å; F158-F165 AromaticContact CE1-CG 3.53Å; F158-F165 HydrophobicContact CE1-CG 3.53Å; F158-F165 AromaticContact CE1-CZ 3.94Å; F158-F165 HydrophobicContact CE1-CZ 3.94Å; F158-F165 HydrophobicContact CG-CD2 4.43Å; F158-F165 HydrophobicContact CG-CE2 4.46Å; F158-V172 HydrophobicContact CE2-CB 4.38Å; F158-V172 HydrophobicContact CE2-CG1 3.95Å; F158-V172 HydrophobicContact CZ-CB 4.1Å; F158-V172 HydrophobicContact CZ-CG1 4Å; F158-F173 HydrophobicContact CB-CB 4.21Å; F158-F173 HydrophobicContact CB-CD2 3.45Å; F158-F173 VanDerWaalsContact CB-CD2 3.45Å; F158-F173 HydrophobicContact CB-CE2 4.22Å; F158-F173 HydrophobicContact CB-CG 4.25Å; F158-F173 HydrophobicContact CD2-CB 4.5Å; F158-F173 HydrophobicContact CG-CB 4.22Å; F158-F173 HydrophobicContact CG-CD2 4.29Å; F158-W424 HydrophobicContact CE2-CB 4.01Å; F158-W424 HydrophobicContact CZ-CB 3.56Å; F158-W424 HydrophobicContact CZ-CD2 4.48Å; F158-W424 HydrophobicContact CZ-CG 4.01Å; F158-V425 HydrophobicContact CE2-CG1 4.33Å
159	A	88.8	Confident	87.9	Confident	40 Å²	40	53.9 Å²	53.9	33%	0.331	26%	0.256	S	S	.	.	H	α-helix	trans	-67.7	-35.1	178.5	0	0	0	0	0	112.8	F155 L156 T157 R162 F173	F155-A159 WeakPolarHBondContact O-CB 3.37Å; F155-A159 PolarHBondContact O-N 3.17Å; L156-A159 WeakPolarHBondContact O-CB 3.36Å; L156-A159 PolarHBondContact O-N 3.17Å; L156-A159 VanDerWaalsContact O-N 3.13Å; T157-A159 VanDerWaalsContact C-N 3.34Å; A159-R162 WeakPolarHBondContact O-CG 2.98Å; A159-F173 HydrophobicContact CB-CE2 4.28Å
160	I	87.7	Confident	87.5	Confident	60 Å²	60	55.6 Å²	55.6	31%	0.308	25%	0.251	S	S	.	.	H	α-helix	trans	-66.7	-42	176.2	-69.2	165.1	0	0	0	110.9	L156 T157 W434 F437	L156-I160 VanDerWaalsContact O-CG1 3.32Å; L156-I160 WeakPolarHBondContact O-CG1 3.3Å; L156-I160 PolarHBondContact O-N 2.76Å; T157-I160 PolarHBondContact O-N 2.65Å; I160-W434 HydrophobicContact CD1-CD2 4.11Å; I160-W434 HydrophobicContact CD1-CE3 4.33Å; I160-W434 HydrophobicContact CD1-CH2 4.26Å; I160-W434 HydrophobicContact CD1-CZ2 4.02Å; I160-W434 HydrophobicContact CD1-CZ3 4.4Å; I160-F437 HydrophobicContact CD1-CB 4.35Å; I160-F437 HydrophobicContact CD1-CD1 4.07Å; I160-F437 HydrophobicContact CD1-CD2 4.42Å; I160-F437 HydrophobicContact CD1-CG 4.02Å; I160-F437 HydrophobicContact CG1-CD2 4.26Å; I160-F437 HydrophobicContact CG1-CG 4.35Å; I160-F437 HydrophobicContact CG2-CB 4.45Å
161	D	80.5	Confident	87.4	Confident	51 Å²	51	54.7 Å²	54.7	27%	0.273	25%	0.245	S	C	.	.	T	Hydrogen-bonded Turn	trans	-119.6	56.6	-175.4	-165.8	1.4	0	0	0	112.8	T157 F158 K163 R164 F165	T157-D161 PolarHBondContact O-N 3.09Å; F158-D161 CarbonylContact O-C 3.55Å; F158-D161 PolarHBondContact O-N 3.43Å; D161-K163 PolarHBondContact O-N 3.28Å; D161-R164 HydrophobicContact CB-CB 4.45Å; D161-R164 VanDerWaalsContact CG-CB 3.43Å; D161-R164 PolarHBondContact O-N 3.25Å; D161-R164 VanDerWaalsContact OD1-CB 3.3Å; D161-R164 WeakPolarHBondContact OD1-CB 3.3Å; D161-R164 WeakPolarHBondContact OD2-CB 3.44Å; D161-R164 WeakPolarHBondContact OD2-CD 3.47Å; D161-R164 IonicContact OD2-NH1 3.79Å; D161-F165 HydrophobicContact CB-CE2 4.35Å; D161-F165 WeakPolarHBondContact O-CD2 3.2Å
162	R	79.5	Confident	87.2	Confident	190 Å²	190	54.7 Å²	54.7	72%	0.717	25%	0.245	S	C	*	.	G	3₁₀ helix	trans	-59.6	-30.3	-175.8	-67.9	-159.1	-71.1	173.2	-2.9	114.3	F158 A159 R164	F158-R162 WeakPolarHBondContact O-CA 3.44Å; F158-R162 WeakPolarHBondContact O-CG 3.44Å; F158-R162 PolarHBondContact O-N 3.17Å; A159-R162 WeakPolarHBondContact O-CG 2.98Å; R162-R164 VanDerWaalsContact C-N 3.3Å; R162-R164 PolarHBondContact O-N 3.21Å
163	K	77.2	Confident	87.1	Confident	199 Å²	199	53 Å²	53	87%	0.865	24%	0.235	S	C	*	.	G	3₁₀ helix	trans	-74.3	-21.4	-175.7	-68.4	-175	179.2	180	0	112.9	D161	D161-K163 PolarHBondContact O-N 3.28Å
164	R	78.9	Confident	87.2	Confident	79 Å²	79	51.3 Å²	51.3	30%	0.298	23%	0.227	S	C	.	.	G	3₁₀ helix	trans	-77	-26.8	-177.5	177	175.3	168.3	-159.3	-10.9	113.7	D161 R162 K429	D161-R164 HydrophobicContact CB-CB 4.45Å; D161-R164 VanDerWaalsContact CG-CB 3.43Å; D161-R164 PolarHBondContact O-N 3.25Å; D161-R164 VanDerWaalsContact OD1-CB 3.3Å; D161-R164 WeakPolarHBondContact OD1-CB 3.3Å; D161-R164 WeakPolarHBondContact OD2-CB 3.44Å; D161-R164 WeakPolarHBondContact OD2-CD 3.47Å; D161-R164 IonicContact OD2-NH1 3.79Å; R162-R164 VanDerWaalsContact C-N 3.3Å; R162-R164 PolarHBondContact O-N 3.21Å; R164-K429 VanDerWaalsContact NH1-CB 3.28Å; R164-K429 VanDerWaalsContact NH2-CD 3.32Å
165	F	78.8	Confident	87.3	Confident	12 Å²	12	51.4 Å²	51.4	5%	0.053	23%	0.227	C	C	.	.			trans	-107.5	100.4	-170.8	-57.2	-77.8	0	0	0	110.9	F158 D161 E169	F158-F165 HydrophobicContact CD1-CB 4.05Å; F158-F165 AromaticContact CD1-CD1 3.89Å; F158-F165 HydrophobicContact CD1-CD1 3.89Å; F158-F165 AromaticContact CD1-CD2 3.35Å; F158-F165 HydrophobicContact CD1-CD2 3.35Å; F158-F165 HydrophobicContact CD1-CE1 4.1Å; F158-F165 AromaticContact CD1-CE2 3.59Å; F158-F165 HydrophobicContact CD1-CE2 3.59Å; F158-F165 AromaticContact CD1-CG 3.49Å; F158-F165 HydrophobicContact CD1-CG 3.49Å; F158-F165 VanDerWaalsContact CD1-CG 3.49Å; F158-F165 AromaticContact CD1-CZ 3.95Å; F158-F165 HydrophobicContact CD1-CZ 3.95Å; F158-F165 HydrophobicContact CE1-CB 4.11Å; F158-F165 AromaticContact CE1-CD1 3.45Å; F158-F165 HydrophobicContact CE1-CD1 3.45Å; F158-F165 VanDerWaalsContact CE1-CD1 3.45Å; F158-F165 AromaticContact CE1-CD2 3.85Å; F158-F165 HydrophobicContact CE1-CD2 3.85Å; F158-F165 AromaticContact CE1-CE1 3.66Å; F158-F165 HydrophobicContact CE1-CE1 3.66Å; F158-F165 HydrophobicContact CE1-CE2 4.04Å; F158-F165 AromaticContact CE1-CG 3.53Å; F158-F165 HydrophobicContact CE1-CG 3.53Å; F158-F165 AromaticContact CE1-CZ 3.94Å; F158-F165 HydrophobicContact CE1-CZ 3.94Å; F158-F165 HydrophobicContact CG-CD2 4.43Å; F158-F165 HydrophobicContact CG-CE2 4.46Å; D161-F165 HydrophobicContact CB-CE2 4.35Å; D161-F165 WeakPolarHBondContact O-CD2 3.2Å; F165-E169 HydrophobicContact CB-CB 4.37Å; F165-E169 HydrophobicContact CD1-CB 4.48Å; F165-E169 WeakPolarHBondContact CD1-OE2 3.33Å
166	R	82.7	Confident	87.4	Confident	126 Å²	126	49.3 Å²	49.3	48%	0.475	22%	0.218	S	C	.	.			trans	-90.1	170.2	174	-66.1	-171.8	176.3	177.3	-9.5	111	E169 R170 P254 E255	R166-E169 WeakPolarHBondContact O-CA 3.39Å; R166-E169 WeakPolarHBondContact O-CB 3.03Å; R166-E169 PolarHBondContact O-N 3.06Å; R166-R170 PolarHBondContact O-N 3.11Å; R166-P254 HydrophobicContact CB-CB 4Å; R166-E255 IonicContact CZ-OE1 3.82Å; R166-E255 IonicContact NH1-OE1 2.79Å; R166-E255 PolarHBondContact NH1-OE1 3.35Å; R166-E255 IonicContact NH1-OE2 2.63Å; R166-E255 IonicContact NH2-OE1 2.7Å
167	F	82.6	Confident	87.6	Confident	6 Å²	6	48.2 Å²	48.2	3%	0.026	21%	0.212	C	C	.	.	T	Hydrogen-bonded Turn	trans	-58.2	140.8	171.4	-76.5	-79.1	0	0	0	110.6	R170 T243 I257 E258 V264	F167-R170 HydrophobicContact CD1-CB 4.26Å; F167-R170 HydrophobicContact CE1-CB 4.28Å; F167-R170 HydrophobicContact CG-CB 4.41Å; F167-R170 HydrophobicContact CZ-CB 4.45Å; F167-R170 HydrophobicContact CZ-CG 4.39Å; F167-T243 HydrophobicContact CD1-CG2 4.39Å; F167-I257 HydrophobicContact CB-CB 4.14Å; F167-I257 HydrophobicContact CB-CG2 3.74Å; F167-I257 HydrophobicContact CD1-CG2 4.17Å; F167-I257 HydrophobicContact CD2-CG2 4.17Å; F167-I257 HydrophobicContact CG-CB 4.5Å; F167-I257 HydrophobicContact CG-CG2 3.77Å; F167-E258 HydrophobicContact CD2-CB 4.3Å; F167-V264 HydrophobicContact CE1-CG1 4.34Å
168	P	82.8	Confident	88	Confident	11 Å²	11	47.9 Å²	47.9	7%	0.071	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	cis	-82.9	-10.2	5.5	33.6	-37.2	0	0	0	115.2	R170 C171 F240 T243 L244 M354	P168-R170 PolarHBondContact O-N 3.36Å; P168-R170 VanDerWaalsContact O-N 3.16Å; P168-C171 WeakPolarHBondContact O-CB 3.5Å; P168-C171 PolarHBondContact O-N 3Å; P168-F240 HydrophobicContact CB-CD2 4.12Å; P168-F240 HydrophobicContact CB-CE2 4.26Å; P168-F240 HydrophobicContact CG-CE2 4.48Å; P168-T243 VanDerWaalsContact CB-OG1 3.23Å; P168-T243 WeakPolarHBondContact CB-OG1 3.14Å; P168-L244 HydrophobicContact CG-CD1 4.46Å; P168-M354 HydrophobicContact CG-CE 3.97Å
169	E	86.8	Confident	88.4	Confident	38 Å²	38	47.9 Å²	47.9	18%	0.178	21%	0.21	C	C	.	.	H	α-helix	trans	-60.2	-30.7	-174.2	-52.8	-178.6	164.4	0	0	112.6	F165 R166 C171 V172 M354 W424	F165-E169 HydrophobicContact CB-CB 4.37Å; F165-E169 HydrophobicContact CD1-CB 4.48Å; F165-E169 WeakPolarHBondContact CD1-OE2 3.33Å; R166-E169 WeakPolarHBondContact O-CA 3.39Å; R166-E169 WeakPolarHBondContact O-CB 3.03Å; R166-E169 PolarHBondContact O-N 3.06Å; E169-C171 PolarHBondContact O-N 2.87Å; E169-V172 VanDerWaalsContact O-CB 3.29Å; E169-V172 WeakPolarHBondContact O-CB 3.33Å; E169-V172 PolarHBondContact O-N 2.89Å; E169-M354 HydrophobicContact CG-CE 3.92Å; E169-W424 HydrophobicContact CB-CE3 4.48Å; E169-W424 HydrophobicContact CB-CZ3 4.19Å; E169-W424 VanDerWaalsContact CD-CZ3 3.49Å; E169-W424 HydrophobicContact CG-CE3 4.32Å; E169-W424 HydrophobicContact CG-CH2 4.02Å; E169-W424 HydrophobicContact CG-CZ3 3.58Å; E169-W424 WeakPolarHBondContact OE1-CZ3 3.24Å
170	R	89.1	Confident	88.8	Confident	77 Å²	77	48.1 Å²	48.1	29%	0.291	20%	0.204	S	C	.	.	H	α-helix	trans	-59.9	-23.7	174.9	-169.7	170.8	175.4	172.9	-4.5	113.9	R166 F167 P168 V172 F173 Y174 E258	R166-R170 PolarHBondContact O-N 3.11Å; F167-R170 HydrophobicContact CD1-CB 4.26Å; F167-R170 HydrophobicContact CE1-CB 4.28Å; F167-R170 HydrophobicContact CG-CB 4.41Å; F167-R170 HydrophobicContact CZ-CB 4.45Å; F167-R170 HydrophobicContact CZ-CG 4.39Å; P168-R170 PolarHBondContact O-N 3.36Å; P168-R170 VanDerWaalsContact O-N 3.16Å; R170-V172 VanDerWaalsContact C-N 3.28Å; R170-V172 PolarHBondContact O-N 3.35Å; R170-F173 WeakPolarHBondContact O-CB 3.36Å; R170-F173 PolarHBondContact O-N 3.19Å; R170-Y174 HydrophobicContact CG-CE2 4.16Å; R170-Y174 WeakPolarHBondContact O-CD2 3.2Å; R170-E258 IonicContact NH1-OE1 3.51Å; R170-E258 PolarHBondContact NH1-OE1 2.67Å
171	C	93.3	Very high	89.3	Confident	0 Å²	0	46.6 Å²	46.6	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-65.4	-33.5	171.9	-65.8	0	0	0	0	111.7	P168 E169 F173 Y174 L175 W236 F240	P168-C171 WeakPolarHBondContact O-CB 3.5Å; P168-C171 PolarHBondContact O-N 3Å; E169-C171 PolarHBondContact O-N 2.87Å; C171-F173 VanDerWaalsContact C-N 3.26Å; C171-F173 PolarHBondContact O-N 3.01Å; C171-Y174 PolarHBondContact O-N 2.93Å; C171-L175 WeakPolarHBondContact O-CB 3.41Å; C171-L175 PolarHBondContact O-N 2.64Å; C171-W236 HydrophobicContact CB-CE3 4.2Å; C171-F240 HydrophobicContact CB-CB 3.73Å; C171-F240 HydrophobicContact CB-CD2 4.38Å
172	V	92.9	Very high	90.2	Very high	0 Å²	0	44.8 Å²	44.8	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-66.3	-30.4	179.5	-174.5	0	0	0	0	111.5	F158 E169 R170 L175 S176 F240 F357 W424	F158-V172 HydrophobicContact CE2-CB 4.38Å; F158-V172 HydrophobicContact CE2-CG1 3.95Å; F158-V172 HydrophobicContact CZ-CB 4.1Å; F158-V172 HydrophobicContact CZ-CG1 4Å; E169-V172 VanDerWaalsContact O-CB 3.29Å; E169-V172 WeakPolarHBondContact O-CB 3.33Å; E169-V172 PolarHBondContact O-N 2.89Å; R170-V172 VanDerWaalsContact C-N 3.28Å; R170-V172 PolarHBondContact O-N 3.35Å; V172-L175 PolarHBondContact O-N 3.21Å; V172-S176 WeakPolarHBondContact O-CB 3.49Å; V172-S176 PolarHBondContact O-N 3.39Å; V172-S176 PolarHBondContact O-OG 3.12Å; V172-F240 HydrophobicContact CG2-CD2 4.05Å; V172-F240 HydrophobicContact CG2-CE2 4.19Å; V172-F357 HydrophobicContact CG1-CE2 4.33Å; V172-F357 HydrophobicContact CG2-CE1 4.3Å; V172-F357 HydrophobicContact CG2-CE2 4.43Å; V172-F357 HydrophobicContact CG2-CZ 3.98Å; V172-W424 HydrophobicContact CG1-CG 4.07Å
173	F	93.6	Very high	91	Very high	29 Å²	29	35.8 Å²	35.8	13%	0.127	15%	0.154	C	C	.	.	H	α-helix	trans	-58.1	-54	173.4	168.8	-108.9	0	0	0	111.6	F155 F158 A159 R170 C171 L175 S176 L177	F155-F173 AromaticContact CD2-CD2 3.75Å; F155-F173 HydrophobicContact CD2-CD2 3.75Å; F155-F173 AromaticContact CD2-CE2 3.37Å; F155-F173 HydrophobicContact CD2-CE2 3.37Å; F155-F173 AromaticContact CD2-CZ 3.95Å; F155-F173 HydrophobicContact CD2-CZ 3.95Å; F155-F173 AromaticContact CE2-CD2 3.97Å; F155-F173 HydrophobicContact CE2-CD2 3.97Å; F155-F173 HydrophobicContact CE2-CE1 4.13Å; F155-F173 AromaticContact CE2-CE2 3.17Å; F155-F173 HydrophobicContact CE2-CE2 3.17Å; F155-F173 AromaticContact CE2-CZ 3.28Å; F155-F173 HydrophobicContact CE2-CZ 3.28Å; F155-F173 HydrophobicContact CG-CE2 4.27Å; F155-F173 AromaticContact CZ-CE2 3.94Å; F155-F173 HydrophobicContact CZ-CE2 3.94Å; F155-F173 AromaticContact CZ-CZ 3.93Å; F155-F173 HydrophobicContact CZ-CZ 3.93Å; F158-F173 HydrophobicContact CB-CB 4.21Å; F158-F173 HydrophobicContact CB-CD2 3.45Å; F158-F173 VanDerWaalsContact CB-CD2 3.45Å; F158-F173 HydrophobicContact CB-CE2 4.22Å; F158-F173 HydrophobicContact CB-CG 4.25Å; F158-F173 HydrophobicContact CD2-CB 4.5Å; F158-F173 HydrophobicContact CG-CB 4.22Å; F158-F173 HydrophobicContact CG-CD2 4.29Å; A159-F173 HydrophobicContact CB-CE2 4.28Å; R170-F173 WeakPolarHBondContact O-CB 3.36Å; R170-F173 PolarHBondContact O-N 3.19Å; C171-F173 VanDerWaalsContact C-N 3.26Å; C171-F173 PolarHBondContact O-N 3.01Å; F173-L175 VanDerWaalsContact C-N 3.35Å; F173-L175 PolarHBondContact O-N 3.28Å; F173-S176 PolarHBondContact O-N 3.37Å; F173-S176 PolarHBondContact O-OG 3.17Å; F173-L177 PolarHBondContact O-N 3.15Å
174	Y	95.8	Very high	92	Very high	40 Å²	40	29 Å²	29	16%	0.157	13%	0.127	C	C	.	.	H	α-helix	trans	-68.5	-35.1	178.8	-61	-70.8	0	0	0	112.3	R170 C171 S176 L177 C178 W236 H265 W269	R170-Y174 HydrophobicContact CG-CE2 4.16Å; R170-Y174 WeakPolarHBondContact O-CD2 3.2Å; C171-Y174 PolarHBondContact O-N 2.93Å; Y174-S176 PolarHBondContact O-N 3.34Å; Y174-L177 PolarHBondContact O-N 2.74Å; Y174-C178 PolarHBondContact O-N 3.11Å; Y174-C178 PolarHBondContact O-SG 2.92Å; Y174-W236 VanDerWaalsContact CB-CE2 3.45Å; Y174-W236 HydrophobicContact CD1-CZ2 4.45Å; Y174-W236 HydrophobicContact CD2-CE3 4.35Å; Y174-W236 AromaticContact CD2-CH2 3.71Å; Y174-W236 HydrophobicContact CD2-CH2 3.71Å; Y174-W236 AromaticContact CD2-CZ2 3.95Å; Y174-W236 HydrophobicContact CD2-CZ2 3.95Å; Y174-W236 AromaticContact CD2-CZ3 3.91Å; Y174-W236 HydrophobicContact CD2-CZ3 3.91Å; Y174-W236 HydrophobicContact CE2-CH2 4.29Å; Y174-W236 HydrophobicContact CG-CD2 4.41Å; Y174-W236 AromaticContact CG-CE2 3.98Å; Y174-W236 HydrophobicContact CG-CH2 4.08Å; Y174-W236 AromaticContact CG-CZ2 3.82Å; Y174-W236 HydrophobicContact CG-CZ2 3.82Å; Y174-W236 HydrophobicContact CG-CZ3 4.45Å; Y174-H265 AromaticContact CD2-CE1 3.92Å; Y174-H265 AromaticContact CE1-CE1 3.87Å; Y174-H265 AromaticContact CE2-CE1 3.34Å; Y174-H265 WeakPolarHBondContact CE2-CE1 3.48Å; Y174-H265 AromaticContact CE2-NE2 3.74Å; Y174-H265 AromaticContact CZ-CE1 3.32Å; Y174-H265 AromaticContact CZ-NE2 3.88Å; Y174-W269 HydrophobicContact CD1-CZ2 4.19Å
175	L	96.2	Very high	92.9	Very high	1 Å²	1	25.2 Å²	25.2	1%	0.005	11%	0.112	C	C	.	.	H	α-helix	trans	-57.5	-47.6	172.6	-179.3	65	0	0	0	111.6	C171 V172 F173 L177 C178 I179 A233 W236 W237 F357 F361	C171-L175 WeakPolarHBondContact O-CB 3.41Å; C171-L175 PolarHBondContact O-N 2.64Å; V172-L175 PolarHBondContact O-N 3.21Å; F173-L175 VanDerWaalsContact C-N 3.35Å; F173-L175 PolarHBondContact O-N 3.28Å; L175-L177 VanDerWaalsContact C-N 3.31Å; L175-L177 PolarHBondContact O-N 3.07Å; L175-C178 WeakPolarHBondContact O-CB 3.39Å; L175-C178 PolarHBondContact O-N 3.06Å; L175-C178 VanDerWaalsContact O-N 3.17Å; L175-I179 HydrophobicContact CD1-CD1 4.07Å; L175-I179 HydrophobicContact CD1-CG1 4.38Å; L175-I179 HydrophobicContact CG-CD1 3.86Å; L175-I179 WeakPolarHBondContact O-CG1 3.44Å; L175-I179 PolarHBondContact O-N 3.45Å; L175-A233 HydrophobicContact CD1-CB 3.76Å; L175-A233 WeakPolarHBondContact CD1-O 3.27Å; L175-W236 HydrophobicContact CB-CB 4.27Å; L175-W236 HydrophobicContact CD1-CB 4.31Å; L175-W237 HydrophobicContact CD1-CB 4.45Å; L175-F357 HydrophobicContact CD2-CE2 4.3Å; L175-F357 HydrophobicContact CD2-CZ 3.74Å; L175-F361 HydrophobicContact CD1-CE2 3.99Å; L175-F361 HydrophobicContact CD1-CZ 4.34Å; L175-F361 HydrophobicContact CD2-CD2 4.31Å; L175-F361 HydrophobicContact CD2-CE2 4.03Å; L175-F361 HydrophobicContact CG-CE2 4.49Å
176	S	96.4	Very high	93.8	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-62.9	-37.1	179.7	67.4	0	0	0	0	112.5	F155 V172 F173 Y174 I179 F180	F155-S176 WeakPolarHBondContact CA-OG 3.46Å; F155-S176 WeakPolarHBondContact CB-OG 3.08Å; F155-S176 PolarHBondContact N-OG 3.04Å; V172-S176 WeakPolarHBondContact O-CB 3.49Å; V172-S176 PolarHBondContact O-N 3.39Å; V172-S176 PolarHBondContact O-OG 3.12Å; F173-S176 PolarHBondContact O-N 3.37Å; F173-S176 PolarHBondContact O-OG 3.17Å; Y174-S176 PolarHBondContact O-N 3.34Å; S176-I179 PolarHBondContact O-N 2.75Å; S176-F180 WeakPolarHBondContact O-CB 3.38Å; S176-F180 PolarHBondContact O-N 3.09Å
177	L	96.9	Very high	94.5	Very high	44 Å²	44	21.3 Å²	21.3	23%	0.23	10%	0.1	C	C	.	.	H	α-helix	trans	-62.8	-45.8	173	-178.6	61.5	0	0	0	111.7	F155 F173 Y174 L175 F180 I181	F155-L177 HydrophobicContact CD2-CB 3.74Å; F155-L177 HydrophobicContact CD2-CD1 4.19Å; F155-L177 HydrophobicContact CD2-CG 4.42Å; F155-L177 HydrophobicContact CE1-CD1 4.48Å; F155-L177 HydrophobicContact CE2-CB 3.88Å; F155-L177 HydrophobicContact CE2-CD1 3.93Å; F155-L177 HydrophobicContact CE2-CD2 4.01Å; F155-L177 HydrophobicContact CE2-CG 4.16Å; F155-L177 HydrophobicContact CZ-CD1 4.1Å; F173-L177 PolarHBondContact O-N 3.15Å; Y174-L177 PolarHBondContact O-N 2.74Å; L175-L177 VanDerWaalsContact C-N 3.31Å; L175-L177 PolarHBondContact O-N 3.07Å; L177-F180 PolarHBondContact O-N 3.21Å; L177-I181 HydrophobicContact CD1-CD1 3.82Å; L177-I181 HydrophobicContact CD1-CG1 4.29Å; L177-I181 HydrophobicContact CG-CD1 3.94Å; L177-I181 WeakPolarHBondContact O-CG1 3.14Å; L177-I181 PolarHBondContact O-N 2.97Å
178	C	98.3	Very high	95	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-62.1	-45.1	178.9	-64.1	0	0	0	0	111.7	Y174 L175 F180 I181 S182 F229 A233 W269	Y174-C178 PolarHBondContact O-N 3.11Å; Y174-C178 PolarHBondContact O-SG 2.92Å; L175-C178 WeakPolarHBondContact O-CB 3.39Å; L175-C178 PolarHBondContact O-N 3.06Å; L175-C178 VanDerWaalsContact O-N 3.17Å; C178-F180 PolarHBondContact O-N 2.79Å; C178-I181 PolarHBondContact O-N 2.9Å; C178-S182 VanDerWaalsContact O-CB 3.31Å; C178-S182 WeakPolarHBondContact O-CB 3.36Å; C178-S182 PolarHBondContact O-N 3.33Å; C178-S182 PolarHBondContact O-OG 3.01Å; C178-F229 HydrophobicContact CB-CB 4.5Å; C178-F229 WeakPolarHBondContact CB-O 3.31Å; C178-A233 HydrophobicContact CB-CB 3.78Å; C178-W269 WeakPolarHBondContact SG-CH2 3.44Å
179	I	97.7	Very high	95.6	Very high	2 Å²	2	23.8 Å²	23.8	1%	0.01	12%	0.116	C	C	.	.	H	α-helix	trans	-62.5	-44.9	179.2	-67.6	171.7	0	0	0	110.7	N147 A151 L175 S176 I181 S182 S183 A233 F361	N147-I179 WeakPolarHBondContact ND2-CG2 3.42Å; A151-I179 HydrophobicContact CB-CB 4.23Å; A151-I179 HydrophobicContact CB-CG2 3.94Å; L175-I179 HydrophobicContact CD1-CD1 4.07Å; L175-I179 HydrophobicContact CD1-CG1 4.38Å; L175-I179 HydrophobicContact CG-CD1 3.86Å; L175-I179 WeakPolarHBondContact O-CG1 3.44Å; L175-I179 PolarHBondContact O-N 3.45Å; S176-I179 PolarHBondContact O-N 2.75Å; I179-I181 PolarHBondContact O-N 3.21Å; I179-S182 WeakPolarHBondContact CA-OG 3.41Å; I179-S182 PolarHBondContact O-N 3.47Å; I179-S182 PolarHBondContact O-OG 3.3Å; I179-S183 PolarHBondContact O-N 3Å; I179-S183 PolarHBondContact O-OG 3.4Å; I179-A233 HydrophobicContact CG1-CB 4.25Å; I179-F361 HydrophobicContact CD1-CE2 4.47Å
180	F	98	Very high	95.9	Very high	46 Å²	46	26.6 Å²	26.6	20%	0.202	13%	0.131	C	C	.	.	H	α-helix	trans	-55.6	-53.7	175.6	167.9	-110.4	0	0	0	111.4	A148 A151 L152 S176 L177 C178 S182 S183 L184	A148-F180 HydrophobicContact CB-CD2 3.99Å; A148-F180 HydrophobicContact CB-CE2 4.3Å; A151-F180 HydrophobicContact CB-CB 3.89Å; L152-F180 HydrophobicContact CB-CD2 3.81Å; L152-F180 HydrophobicContact CB-CE2 4.03Å; L152-F180 HydrophobicContact CB-CG 4.41Å; L152-F180 HydrophobicContact CD1-CE1 4.45Å; L152-F180 HydrophobicContact CD1-CE2 4.34Å; L152-F180 HydrophobicContact CD1-CZ 4.3Å; L152-F180 HydrophobicContact CD2-CE2 4.11Å; L152-F180 HydrophobicContact CD2-CZ 4.46Å; L152-F180 HydrophobicContact CG-CE2 4.39Å; S176-F180 WeakPolarHBondContact O-CB 3.38Å; S176-F180 PolarHBondContact O-N 3.09Å; L177-F180 PolarHBondContact O-N 3.21Å; C178-F180 PolarHBondContact O-N 2.79Å; F180-S182 PolarHBondContact O-N 2.85Å; F180-S183 WeakPolarHBondContact O-CB 3.38Å; F180-S183 PolarHBondContact O-N 3.43Å; F180-L184 HydrophobicContact CE1-CD1 4.4Å; F180-L184 HydrophobicContact CE2-CD2 3.99Å; F180-L184 HydrophobicContact CZ-CD1 4.49Å; F180-L184 HydrophobicContact CZ-CD2 3.98Å
181	I	98.4	Very high	96.2	Very high	27 Å²	27	31.4 Å²	31.4	14%	0.138	16%	0.155	C	C	.	.	H	α-helix	trans	-65.3	-40.8	-176.5	-61.7	170.1	0	0	0	111.2	L177 C178 I179 S183 L184 L225 F229	L177-I181 HydrophobicContact CD1-CD1 3.82Å; L177-I181 HydrophobicContact CD1-CG1 4.29Å; L177-I181 HydrophobicContact CG-CD1 3.94Å; L177-I181 WeakPolarHBondContact O-CG1 3.14Å; L177-I181 PolarHBondContact O-N 2.97Å; C178-I181 PolarHBondContact O-N 2.9Å; I179-I181 PolarHBondContact O-N 3.21Å; I181-S183 PolarHBondContact O-N 3.36Å; I181-S183 VanDerWaalsContact O-N 3.16Å; I181-L184 WeakPolarHBondContact O-CB 3.35Å; I181-L184 PolarHBondContact O-N 2.79Å; I181-L184 VanDerWaalsContact O-N 3.13Å; I181-L225 HydrophobicContact CG2-CD2 3.54Å; I181-F229 HydrophobicContact CB-CB 4.44Å; I181-F229 HydrophobicContact CB-CD1 4.01Å; I181-F229 HydrophobicContact CB-CD2 4.13Å; I181-F229 HydrophobicContact CB-CE1 4.27Å; I181-F229 HydrophobicContact CB-CE2 4.39Å; I181-F229 HydrophobicContact CB-CG 3.92Å; I181-F229 HydrophobicContact CB-CZ 4.44Å; I181-F229 HydrophobicContact CD1-CD1 3.92Å; I181-F229 HydrophobicContact CD1-CE1 3.44Å; I181-F229 VanDerWaalsContact CD1-CE1 3.44Å; I181-F229 HydrophobicContact CD1-CZ 3.78Å; I181-F229 HydrophobicContact CG1-CE1 4.45Å; I181-F229 HydrophobicContact CG2-CB 4.48Å; I181-F229 HydrophobicContact CG2-CD1 4.09Å; I181-F229 HydrophobicContact CG2-CD2 3.38Å; I181-F229 HydrophobicContact CG2-CE1 4.13Å; I181-F229 HydrophobicContact CG2-CE2 3.44Å; I181-F229 VanDerWaalsContact CG2-CE2 3.44Å; I181-F229 HydrophobicContact CG2-CG 3.72Å; I181-F229 HydrophobicContact CG2-CZ 3.81Å
182	S	97.7	Very high	96.2	Very high	14 Å²	14	33.3 Å²	33.3	10%	0.098	17%	0.165	C	C	.	.	H	α-helix	trans	-64.7	-18.1	178.5	71.9	0	0	0	0	114.7	C178 I179 F180 L225 N226	C178-S182 VanDerWaalsContact O-CB 3.31Å; C178-S182 WeakPolarHBondContact O-CB 3.36Å; C178-S182 PolarHBondContact O-N 3.33Å; C178-S182 PolarHBondContact O-OG 3.01Å; I179-S182 WeakPolarHBondContact CA-OG 3.41Å; I179-S182 PolarHBondContact O-N 3.47Å; I179-S182 PolarHBondContact O-OG 3.3Å; F180-S182 PolarHBondContact O-N 2.85Å; S182-L225 VanDerWaalsContact CA-O 3.3Å; S182-L225 WeakPolarHBondContact CA-O 3.24Å; S182-N226 PolarHBondContact O-ND2 3.4Å
183	S	97.9	Very high	96.3	Very high	0 Å²	0	38.9 Å²	38.9	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-85.6	-22.3	177.5	-55.3	0	0	0	0	113	N147 I179 F180 I181 Y186	N147-S183 PolarHBondContact ND2-OG 3.4Å; I179-S183 PolarHBondContact O-N 3Å; I179-S183 PolarHBondContact O-OG 3.4Å; F180-S183 WeakPolarHBondContact O-CB 3.38Å; F180-S183 PolarHBondContact O-N 3.43Å; I181-S183 PolarHBondContact O-N 3.36Å; I181-S183 VanDerWaalsContact O-N 3.16Å; S183-Y186 PolarHBondContact O-N 3.16Å; S183-Y186 VanDerWaalsContact O-N 3.16Å
184	L	97.5	Very high	96.2	Very high	57 Å²	57	38 Å²	38	30%	0.298	19%	0.192	S	C	.	.	G	3₁₀ helix	trans	-59.1	-39.8	-175.3	-61.2	178.9	0	0	0	114.1	F180 I181 Y186 L187 T188	F180-L184 HydrophobicContact CE1-CD1 4.4Å; F180-L184 HydrophobicContact CE2-CD2 3.99Å; F180-L184 HydrophobicContact CZ-CD1 4.49Å; F180-L184 HydrophobicContact CZ-CD2 3.98Å; I181-L184 WeakPolarHBondContact O-CB 3.35Å; I181-L184 PolarHBondContact O-N 2.79Å; I181-L184 VanDerWaalsContact O-N 3.13Å; L184-Y186 PolarHBondContact O-N 3.1Å; L184-L187 HydrophobicContact CD2-CD1 4.39Å; L184-L187 WeakPolarHBondContact O-CB 3.4Å; L184-L187 PolarHBondContact O-N 3.47Å; L184-T188 PolarHBondContact O-N 2.9Å
185	P	97.3	Very high	96	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	20%	0.202	C	C	.	.	G	3₁₀ helix	trans	-56.1	-36.4	176.9	-30.2	40.2	0	0	0	113.1	L187 T188 L225 N226 L293	P185-L187 PolarHBondContact O-N 3Å; P185-T188 WeakPolarHBondContact O-CB 3.46Å; P185-T188 WeakPolarHBondContact O-CG2 3.35Å; P185-T188 PolarHBondContact O-N 3.44Å; P185-T188 PolarHBondContact O-OG1 3.31Å; P185-L225 HydrophobicContact CG-CB 3.48Å; P185-L225 VanDerWaalsContact CG-CB 3.48Å; P185-L225 HydrophobicContact CG-CD1 4.29Å; P185-N226 HydrophobicContact CG-CB 4.17Å; P185-L293 HydrophobicContact CB-CD1 4.06Å; P185-L293 HydrophobicContact CB-CD2 4.04Å; P185-L293 VanDerWaalsContact O-CD2 3.3Å; P185-L293 WeakPolarHBondContact O-CD2 3.46Å
186	Y	97.4	Very high	95.9	Very high	24 Å²	24	42.8 Å²	42.8	9%	0.094	22%	0.223	C	C	.	.	G	3₁₀ helix	trans	-70.9	-13.5	178.5	-63.8	-80.9	0	0	0	114	A144 S183 L184 P189 N226 L293 V411 L415	A144-Y186 HydrophobicContact CB-CG 4.47Å; S183-Y186 PolarHBondContact O-N 3.16Å; S183-Y186 VanDerWaalsContact O-N 3.16Å; L184-Y186 PolarHBondContact O-N 3.1Å; Y186-P189 VanDerWaalsContact O-CD 3.22Å; Y186-P189 WeakPolarHBondContact O-CD 3.34Å; Y186-N226 WeakPolarHBondContact CE2-ND2 3.22Å; Y186-L293 HydrophobicContact CD1-CD1 3.43Å; Y186-L293 VanDerWaalsContact CD1-CD1 3.43Å; Y186-L293 HydrophobicContact CD2-CD1 4.35Å; Y186-L293 HydrophobicContact CE1-CD1 3.53Å; Y186-L293 HydrophobicContact CE2-CD1 4.46Å; Y186-L293 HydrophobicContact CG-CD1 3.87Å; Y186-V411 HydrophobicContact CD1-CG1 4.08Å; Y186-V411 HydrophobicContact CE1-CG1 3.53Å; Y186-V411 HydrophobicContact CE1-CG2 4.47Å; Y186-L415 HydrophobicContact CD2-CD1 4.48Å; Y186-L415 HydrophobicContact CD2-CD2 3.85Å; Y186-L415 HydrophobicContact CE2-CD2 4.13Å; Y186-L415 HydrophobicContact CG-CD1 4.33Å; Y186-L415 HydrophobicContact CG-CD2 4.44Å
187	L	97.2	Very high	95.7	Very high	32 Å²	32	43 Å²	43	17%	0.168	22%	0.224	C	C	.	.	G	3₁₀ helix	trans	-92.8	-15.4	174.9	-60.8	178.3	0	0	0	113.1	I141 A144 A145 A148 L184 P185 P189 L190	I141-L187 HydrophobicContact CG2-CD2 4.4Å; A144-L187 HydrophobicContact CB-CD2 3.84Å; A144-L187 HydrophobicContact CB-CG 4.16Å; A145-L187 HydrophobicContact CB-CD2 4.03Å; A148-L187 HydrophobicContact CB-CD1 4.35Å; L184-L187 HydrophobicContact CD2-CD1 4.39Å; L184-L187 WeakPolarHBondContact O-CB 3.4Å; L184-L187 PolarHBondContact O-N 3.47Å; P185-L187 PolarHBondContact O-N 3Å; L187-P189 VanDerWaalsContact C-N 3.27Å; L187-L190 HydrophobicContact CD2-CD1 4.44Å; L187-L190 VanDerWaalsContact O-CB 3.3Å; L187-L190 WeakPolarHBondContact O-CB 3.39Å; L187-L190 WeakPolarHBondContact O-CG 3.27Å; L187-L190 PolarHBondContact O-N 3.27Å
188	T	95	Very high	95.5	Very high	34 Å²	34	41 Å²	41	21%	0.209	21%	0.213	C	C	.	.	G	3₁₀ helix	trans	-56.8	-26.9	176.8	64.6	0	0	0	0	115.5	L184 P185 L190 F191 I192 R197	L184-T188 PolarHBondContact O-N 2.9Å; P185-T188 WeakPolarHBondContact O-CB 3.46Å; P185-T188 WeakPolarHBondContact O-CG2 3.35Å; P185-T188 PolarHBondContact O-N 3.44Å; P185-T188 PolarHBondContact O-OG1 3.31Å; T188-L190 PolarHBondContact O-N 2.86Å; T188-L190 VanDerWaalsContact O-N 3.13Å; T188-F191 PolarHBondContact O-N 3.27Å; T188-F191 VanDerWaalsContact O-N 3.17Å; T188-I192 PolarHBondContact O-N 2.93Å; T188-R197 WeakPolarHBondContact OG1-CD 3.29Å
189	P	93.7	Very high	95.2	Very high	34 Å²	34	41.6 Å²	41.6	22%	0.221	22%	0.217	C	C	.	.	G	3₁₀ helix	trans	-63.3	-12	173.1	-19.1	32	0	0	0	115.2	I141 Y186 L187 F191	I141-P189 HydrophobicContact CD1-CB 3.97Å; I141-P189 HydrophobicContact CG1-CB 4.38Å; I141-P189 HydrophobicContact CG1-CG 4.41Å; Y186-P189 VanDerWaalsContact O-CD 3.22Å; Y186-P189 WeakPolarHBondContact O-CD 3.34Å; L187-P189 VanDerWaalsContact C-N 3.27Å; P189-F191 VanDerWaalsContact C-N 3.29Å
190	L	94.4	Very high	94.9	Very high	98 Å²	98	43.9 Å²	43.9	51%	0.513	23%	0.228	S	C	.	.	G	3₁₀ helix	trans	-72.3	-22.5	174.4	-68.1	173.4	0	0	0	113.2	I141 L187 T188	I141-L190 HydrophobicContact CD1-CD2 4.35Å; I141-L190 HydrophobicContact CG2-CD1 4.17Å; I141-L190 HydrophobicContact CG2-CD2 3.84Å; I141-L190 HydrophobicContact CG2-CG 4.05Å; L187-L190 HydrophobicContact CD2-CD1 4.44Å; L187-L190 VanDerWaalsContact O-CB 3.3Å; L187-L190 WeakPolarHBondContact O-CB 3.39Å; L187-L190 WeakPolarHBondContact O-CG 3.27Å; L187-L190 PolarHBondContact O-N 3.27Å; T188-L190 PolarHBondContact O-N 2.86Å; T188-L190 VanDerWaalsContact O-N 3.13Å
191	F	94.3	Very high	94.3	Very high	177 Å²	177	45 Å²	45	78%	0.776	25%	0.246	S	C	*	.	T	Hydrogen-bonded Turn	trans	-127.9	-21.1	-170.5	-51.2	-70	0	0	0	113.6	T188 P189	T188-F191 PolarHBondContact O-N 3.27Å; T188-F191 VanDerWaalsContact O-N 3.17Å; P189-F191 VanDerWaalsContact C-N 3.29Å
192	I	94.5	Very high	93.6	Very high	41 Å²	41	45 Å²	45	21%	0.21	25%	0.246	C	C	.	.	S	Bend	trans	-127.9	149.7	-173.8	-54.4	178.2	0	0	0	107.8	T188 I196 R197 Y218	T188-I192 PolarHBondContact O-N 2.93Å; I192-I196 HydrophobicContact CG2-CB 3.81Å; I192-I196 HydrophobicContact CG2-CD1 4.44Å; I192-I196 HydrophobicContact CG2-CG2 3.76Å; I192-R197 HydrophobicContact CB-CG 4.26Å; I192-R197 HydrophobicContact CG2-CG 3.74Å; I192-R197 PolarHBondContact O-NH1 2.9Å; I192-Y218 HydrophobicContact CD1-CD1 3.83Å; I192-Y218 HydrophobicContact CD1-CE1 3.58Å
193	D	93.3	Very high	92.6	Very high	117 Å²	117	48.9 Å²	48.9	63%	0.626	29%	0.288	S	S	*	.			trans	-84.4	156.1	174.7	-70.5	-45.8	0	0	0	112.9	P195 I196 R197	D193-P195 VanDerWaalsContact C-CD 3.47Å; D193-I196 PolarHBondContact O-N 2.89Å; D193-R197 PolarHBondContact O-N 2.88Å; D193-R197 PolarHBondContact O-NH1 2.95Å
194	A	92.5	Very high	91.6	Very high	10 Å²	10	53.4 Å²	53.4	8%	0.083	31%	0.312	C	S	.	.	H	α-helix	trans	-57.1	-41.3	-178.3	0	0	0	0	0	115	I196 R197 S198 A292	A194-I196 PolarHBondContact O-N 3.36Å; A194-R197 PolarHBondContact O-N 2.92Å; A194-S198 PolarHBondContact O-N 3.49Å; A194-S198 PolarHBondContact O-OG 2.97Å; A194-A292 HydrophobicContact CB-CB 3.65Å
195	P	92.5	Very high	90.8	Very high	55 Å²	55	54.1 Å²	54.1	36%	0.357	33%	0.334	S	S	.	.	H	α-helix	trans	-61.7	-41.5	178.7	-21.6	33	0	0	0	112.8	Q123 D193 R197 S198 C199	Q123-P195 HydrophobicContact CG-CG 3.87Å; D193-P195 VanDerWaalsContact C-CD 3.47Å; P195-R197 VanDerWaalsContact C-N 3.29Å; P195-R197 PolarHBondContact O-N 2.67Å; P195-S198 PolarHBondContact O-N 3.04Å; P195-C199 VanDerWaalsContact O-CB 3.27Å; P195-C199 WeakPolarHBondContact O-CB 3.43Å; P195-C199 PolarHBondContact O-N 3.32Å
196	I	92.4	Very high	90.1	Very high	87 Å²	87	61.8 Å²	61.8	45%	0.446	36%	0.363	S	S	.	.	H	α-helix	trans	-63.5	-37.7	-178.2	-61.8	172.5	0	0	0	110.9	I192 D193 A194 N216 Y218	I192-I196 HydrophobicContact CG2-CB 3.81Å; I192-I196 HydrophobicContact CG2-CD1 4.44Å; I192-I196 HydrophobicContact CG2-CG2 3.76Å; D193-I196 PolarHBondContact O-N 2.89Å; A194-I196 PolarHBondContact O-N 3.36Å; I196-N216 PolarHBondContact O-ND2 3.43Å; I196-Y218 HydrophobicContact CG2-CD2 3.8Å; I196-Y218 HydrophobicContact CG2-CE2 3.72Å
197	R	93.5	Very high	89.7	Confident	5 Å²	5	62.9 Å²	62.9	2%	0.019	37%	0.374	C	S	.	.	H	α-helix	trans	-75	-27.7	-178.1	-67.7	-165.9	-60.4	-83.2	3.1	115.4	T188 I192 D193 A194 P195 A292	T188-R197 WeakPolarHBondContact OG1-CD 3.29Å; I192-R197 HydrophobicContact CB-CG 4.26Å; I192-R197 HydrophobicContact CG2-CG 3.74Å; I192-R197 PolarHBondContact O-NH1 2.9Å; D193-R197 PolarHBondContact O-N 2.88Å; D193-R197 PolarHBondContact O-NH1 2.95Å; A194-R197 PolarHBondContact O-N 2.92Å; P195-R197 VanDerWaalsContact C-N 3.29Å; P195-R197 PolarHBondContact O-N 2.67Å; R197-A292 WeakPolarHBondContact CB-O 3.39Å; R197-A292 PolarHBondContact NE-O 3.31Å
198	S	93.1	Very high	89.3	Confident	1 Å²	1	61.8 Å²	61.8	1%	0.007	37%	0.368	C	S	.	.	H	α-helix	trans	-132.6	-8.4	-161.2	62.4	0	0	0	0	115	A194 P195 L209 S210 A287	A194-S198 PolarHBondContact O-N 3.49Å; A194-S198 PolarHBondContact O-OG 2.97Å; P195-S198 PolarHBondContact O-N 3.04Å; S198-L209 WeakPolarHBondContact O-CD1 3.03Å; S198-S210 PolarHBondContact O-N 3.34Å; S198-S210 PolarHBondContact O-OG 3.46Å; S198-A287 WeakPolarHBondContact O-CB 3.32Å
199	C	91.9	Very high	89.1	Confident	13 Å²	13	60.5 Å²	60.5	9%	0.088	36%	0.359	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.6	155.8	-177.3	-57.7	0	0	0	0	112.7	C122 P195 Y208 N216	C122-C199 HydrophobicContact CB-CB 3.68Å; C122-C199 WeakPolarHBondContact CB-SG 3.29Å; C122-C199 WeakPolarHBondContact SG-CB 3.48Å; C122-C199 CovalentContact SG-SG 2.02Å; C122-C199 PolarHBondContact SG-SG 3.47Å; P195-C199 VanDerWaalsContact O-CB 3.27Å; P195-C199 WeakPolarHBondContact O-CB 3.43Å; P195-C199 PolarHBondContact O-N 3.32Å; C199-Y208 CarbonylContact C-O 3.45Å; C199-Y208 VanDerWaalsContact CA-O 3.23Å; C199-Y208 WeakPolarHBondContact CA-O 3.19Å; C199-Y208 WeakPolarHBondContact CB-O 3.28Å; C199-N216 PolarHBondContact O-ND2 3.37Å
200	H	89.6	Confident	89	Confident	49 Å²	49	59 Å²	59	23%	0.227	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.1	142.8	170.7	-174.9	93.5	0	0	0	109.4	S207 Y208 D215	H200-S207 CarbonylContact O-C 3.57Å; H200-S207 WeakPolarHBondContact O-CA 3.4Å; H200-S207 VanDerWaalsContact O-CB 3.3Å; H200-S207 WeakPolarHBondContact O-CB 3.5Å; H200-Y208 HydrophobicContact CB-CD1 4.45Å; H200-Y208 HydrophobicContact CB-CE1 3.92Å; H200-Y208 AromaticContact CD2-CE1 3.57Å; H200-Y208 AromaticContact CD2-CZ 3.98Å; H200-Y208 PolarHBondContact N-O 3.44Å; H200-Y208 PolarHBondContact O-N 3.05Å; H200-D215 VanDerWaalsContact CE1-CB 3.48Å; H200-D215 WeakPolarHBondContact CE1-CB 3.21Å; H200-D215 IonicContact CE1-OD2 3.07Å
201	A	87.2	Confident	88.7	Confident	71 Å²	71	57.1 Å²	57.1	59%	0.587	34%	0.339	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-100.4	132.1	-178.9	0	0	0	0	0	110.8
202	L	82.3	Confident	87.9	Confident	25 Å²	25	49.6 Å²	49.6	13%	0.131	31%	0.312	C	S	.	.			trans	-81.1	154.6	168.1	-96.6	70.6	0	0	0	110.1	N204 G205 R206 Y208	L202-N204 WeakPolarHBondContact CB-OD1 3.38Å; L202-N204 PolarHBondContact O-N 2.94Å; L202-G205 PolarHBondContact O-N 3.19Å; L202-R206 PolarHBondContact N-O 2.95Å; L202-Y208 HydrophobicContact CD1-CD1 3.27Å; L202-Y208 HydrophobicContact CD1-CE1 3.24Å
203	G	77.8	Confident	86.8	Confident	96 Å²	96	48.7 Å²	48.7	99%	0.99	31%	0.308	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.6	-13.2	173.6	0	0	0	0	0	114.9	G205	G203-G205 VanDerWaalsContact C-N 3.33Å
204	N	77	Confident	86.1	Confident	95 Å²	95	47.3 Å²	47.3	51%	0.508	30%	0.297	S	S	.	.	T	Hydrogen-bonded Turn	trans	-88.5	7.4	175.8	67.2	11.9	0	0	0	113.9	L202 R206	L202-N204 WeakPolarHBondContact CB-OD1 3.38Å; L202-N204 PolarHBondContact O-N 2.94Å; N204-R206 VanDerWaalsContact C-N 3.3Å; N204-R206 PolarHBondContact O-N 2.81Å; N204-R206 WeakPolarHBondContact OD1-CB 3.18Å; N204-R206 PolarHBondContact OD1-N 3.38Å
205	G	79	Confident	85.6	Confident	73 Å²	73	52.5 Å²	52.5	75%	0.753	32%	0.323	S	S	*	.	S	Bend	trans	81.7	-3.6	179.4	0	0	0	0	0	115.4	L202 G203	L202-G205 PolarHBondContact O-N 3.19Å; G203-G205 VanDerWaalsContact C-N 3.33Å
206	R	83.7	Confident	85.5	Confident	161 Å²	161	50.7 Å²	50.7	61%	0.608	31%	0.311	S	S	*	.			trans	-84	151.4	170.5	-60	-173.3	-173	-175.3	3.8	110.1	L202 N204	L202-R206 PolarHBondContact N-O 2.95Å; N204-R206 VanDerWaalsContact C-N 3.3Å; N204-R206 PolarHBondContact O-N 2.81Å; N204-R206 WeakPolarHBondContact OD1-CB 3.18Å; N204-R206 PolarHBondContact OD1-N 3.38Å
207	S	88.8	Confident	85.5	Confident	46 Å²	46	50.3 Å²	50.3	32%	0.322	32%	0.315	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.4	147.9	173.1	52.4	0	0	0	0	111	C122 H200	C122-S207 WeakPolarHBondContact CB-OG 3.37Å; C122-S207 PolarHBondContact N-O 3.49Å; H200-S207 CarbonylContact O-C 3.57Å; H200-S207 WeakPolarHBondContact O-CA 3.4Å; H200-S207 VanDerWaalsContact O-CB 3.3Å; H200-S207 WeakPolarHBondContact O-CB 3.5Å
208	Y	89.5	Confident	85.5	Confident	10 Å²	10	55.3 Å²	55.3	4%	0.039	34%	0.335	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.8	159.7	-179.3	71.7	-82.3	0	0	0	110.6	V109 A119 F120 C199 H200 L202 S210	V109-Y208 HydrophobicContact CG1-CE1 4.2Å; V109-Y208 HydrophobicContact CG1-CE2 4.03Å; V109-Y208 HydrophobicContact CG2-CD2 3.87Å; V109-Y208 HydrophobicContact CG2-CE2 3.83Å; V109-Y208 HydrophobicContact CG2-CG 4.31Å; A119-Y208 HydrophobicContact CB-CD2 3.58Å; A119-Y208 HydrophobicContact CB-CE2 4.47Å; A119-Y208 HydrophobicContact CB-CG 4.09Å; F120-Y208 CarbonylContact O-C 3.56Å; F120-Y208 VanDerWaalsContact O-CA 3.26Å; F120-Y208 WeakPolarHBondContact O-CA 3.44Å; F120-Y208 WeakPolarHBondContact O-CB 3.14Å; C199-Y208 CarbonylContact C-O 3.45Å; C199-Y208 VanDerWaalsContact CA-O 3.23Å; C199-Y208 WeakPolarHBondContact CA-O 3.19Å; C199-Y208 WeakPolarHBondContact CB-O 3.28Å; H200-Y208 HydrophobicContact CB-CD1 4.45Å; H200-Y208 HydrophobicContact CB-CE1 3.92Å; H200-Y208 AromaticContact CD2-CE1 3.57Å; H200-Y208 AromaticContact CD2-CZ 3.98Å; H200-Y208 PolarHBondContact N-O 3.44Å; H200-Y208 PolarHBondContact O-N 3.05Å; L202-Y208 HydrophobicContact CD1-CD1 3.27Å; L202-Y208 HydrophobicContact CD1-CE1 3.24Å; Y208-S210 PolarHBondContact O-N 2.87Å
209	L	90.7	Very high	85.5	Confident	7 Å²	7	55.4 Å²	55.4	4%	0.037	34%	0.336	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-69.6	126.3	176.3	-164.7	66.8	0	0	0	109.2	F120 S198 I211 A287 E289 L299	F120-L209 HydrophobicContact CB-CB 4.31Å; F120-L209 HydrophobicContact CD2-CD2 4.49Å; F120-L209 PolarHBondContact O-N 2.78Å; S198-L209 WeakPolarHBondContact O-CD1 3.03Å; L209-I211 WeakPolarHBondContact O-CG1 3.37Å; L209-I211 PolarHBondContact O-N 3.25Å; L209-A287 HydrophobicContact CD1-CB 3.62Å; L209-A287 HydrophobicContact CD2-CB 4.37Å; L209-A287 VanDerWaalsContact CD2-O 3.27Å; L209-A287 WeakPolarHBondContact CD2-O 3.23Å; L209-A287 HydrophobicContact CG-CB 3.6Å; L209-E289 HydrophobicContact CD2-CB 4.27Å; L209-L299 HydrophobicContact CD2-CD1 3.97Å
210	S	90.9	Very high	85.7	Confident	2 Å²	2	57.1 Å²	57.1	1%	0.014	34%	0.344	C	S	.	.			trans	-58.4	123.6	-172.9	-63.1	0	0	0	0	112.2	S198 Y208 A287	S198-S210 PolarHBondContact O-N 3.34Å; S198-S210 PolarHBondContact O-OG 3.46Å; Y208-S210 PolarHBondContact O-N 2.87Å; S210-A287 PolarHBondContact O-N 2.94Å
211	I	87.9	Confident	85.9	Confident	58 Å²	58	56.8 Å²	56.8	30%	0.297	35%	0.349	S	S	.	.	B	Isolated β-bridge	trans	-134.1	122.4	178.3	-62.7	161.3	0	0	0	108	A119 L209 T213 L299	A119-I211 HydrophobicContact CB-CD1 3.58Å; L209-I211 WeakPolarHBondContact O-CG1 3.37Å; L209-I211 PolarHBondContact O-N 3.25Å; I211-T213 PolarHBondContact O-N 3.19Å; I211-L299 HydrophobicContact CD1-CD1 3.88Å; I211-L299 HydrophobicContact CG1-CD1 3.92Å
212	G	78.6	Confident	86.3	Confident	20 Å²	20	53.7 Å²	53.7	21%	0.206	32%	0.323	C	S	.	.	S	Bend	trans	63.7	-4.7	171.7	0	0	0	0	0	116.6	N283 V285	G212-N283 WeakPolarHBondContact CA-O 3.35Å; G212-V285 PolarHBondContact N-O 3.5Å
213	T	71	Confident	87	Confident	22 Å²	22	52.5 Å²	52.5	14%	0.135	32%	0.317	C	S	.	.			trans	-96.5	142.8	178.6	171	0	0	0	0	111.8	I211 D215	I211-T213 PolarHBondContact O-N 3.19Å; T213-D215 WeakPolarHBondContact OG1-CB 3.47Å; T213-D215 PolarHBondContact OG1-N 3.42Å; T213-D215 PolarHBondContact OG1-OD2 3.37Å
214	F	77.9	Confident	88	Confident	88 Å²	88	51.1 Å²	51.1	39%	0.386	29%	0.287	S	S	.	.			trans	-97.4	4.3	175.4	-53.3	-60.7	0	0	0	113.4	N216 L220 L280 N283	F214-N216 VanDerWaalsContact C-N 3.27Å; F214-N216 PolarHBondContact O-N 3.25Å; F214-L220 HydrophobicContact CD1-CD1 4.16Å; F214-L280 HydrophobicContact CD1-CD2 4.33Å; F214-L280 HydrophobicContact CE1-CD2 3.54Å; F214-L280 HydrophobicContact CZ-CD2 4.22Å; F214-N283 WeakPolarHBondContact CE2-OD1 3.27Å; F214-N283 WeakPolarHBondContact CZ-OD1 3.24Å
215	D	82.3	Confident	88.9	Confident	119 Å²	119	49.3 Å²	49.3	64%	0.636	28%	0.277	S	S	*	.			trans	-70.4	-26	-173.2	-58.4	-37	0	0	0	112.4	H200 T213 S217	H200-D215 VanDerWaalsContact CE1-CB 3.48Å; H200-D215 WeakPolarHBondContact CE1-CB 3.21Å; H200-D215 IonicContact CE1-OD2 3.07Å; T213-D215 WeakPolarHBondContact OG1-CB 3.47Å; T213-D215 PolarHBondContact OG1-N 3.42Å; T213-D215 PolarHBondContact OG1-OD2 3.37Å; D215-S217 PolarHBondContact O-N 3.01Å
216	N	90.2	Very high	89.7	Confident	17 Å²	17	46.9 Å²	46.9	9%	0.091	25%	0.247	C	C	.	.			trans	-90.7	102.4	173.6	-172.3	-36.7	0	0	0	110.2	I196 C199 F214 Y218 C219 L220	I196-N216 PolarHBondContact O-ND2 3.43Å; C199-N216 PolarHBondContact O-ND2 3.37Å; F214-N216 VanDerWaalsContact C-N 3.27Å; F214-N216 PolarHBondContact O-N 3.25Å; N216-Y218 VanDerWaalsContact C-N 3.32Å; N216-Y218 PolarHBondContact O-N 3.04Å; N216-Y218 WeakPolarHBondContact OD1-CB 3.09Å; N216-Y218 PolarHBondContact OD1-N 3.27Å; N216-C219 HydrophobicContact CB-CB 3.79Å; N216-C219 WeakPolarHBondContact O-CB 3.35Å; N216-C219 PolarHBondContact O-N 3.31Å; N216-C219 PolarHBondContact OD1-N 2.84Å; N216-L220 PolarHBondContact O-N 3.46Å
217	S	92.3	Very high	90.4	Very high	78 Å²	78	39.7 Å²	39.7	55%	0.545	22%	0.22	S	C	.	.	H	α-helix	trans	-62.6	-34	179.8	59	0	0	0	0	113.5	D215 L220 A221	D215-S217 PolarHBondContact O-N 3.01Å; S217-L220 PolarHBondContact O-N 2.82Å; S217-A221 VanDerWaalsContact O-CB 3.24Å; S217-A221 WeakPolarHBondContact O-CB 3.3Å; S217-A221 PolarHBondContact O-N 3.16Å
218	Y	93.1	Very high	90.8	Very high	111 Å²	111	39.2 Å²	39.2	44%	0.435	21%	0.212	S	C	.	.	H	α-helix	trans	-67.9	-38.1	175.9	-63	-77	0	0	0	112	I192 I196 N216 S222	I192-Y218 HydrophobicContact CD1-CD1 3.83Å; I192-Y218 HydrophobicContact CD1-CE1 3.58Å; I196-Y218 HydrophobicContact CG2-CD2 3.8Å; I196-Y218 HydrophobicContact CG2-CE2 3.72Å; N216-Y218 VanDerWaalsContact C-N 3.32Å; N216-Y218 PolarHBondContact O-N 3.04Å; N216-Y218 WeakPolarHBondContact OD1-CB 3.09Å; N216-Y218 PolarHBondContact OD1-N 3.27Å; Y218-S222 WeakPolarHBondContact O-CB 3.31Å; Y218-S222 PolarHBondContact O-N 3.44Å; Y218-S222 PolarHBondContact O-OG 3.44Å
219	C	94.1	Very high	91.2	Very high	3 Å²	3	40.6 Å²	40.6	2%	0.02	22%	0.218	C	C	.	.	H	α-helix	trans	-63.2	-51.6	174	179.2	0	0	0	0	110.3	N216 A221 S222 F223 C294	N216-C219 HydrophobicContact CB-CB 3.79Å; N216-C219 WeakPolarHBondContact O-CB 3.35Å; N216-C219 PolarHBondContact O-N 3.31Å; N216-C219 PolarHBondContact OD1-N 2.84Å; C219-A221 VanDerWaalsContact C-N 3.35Å; C219-A221 PolarHBondContact O-N 2.87Å; C219-S222 PolarHBondContact O-N 3.4Å; C219-F223 PolarHBondContact O-N 3.17Å; C219-C294 WeakPolarHBondContact CA-SG 3.46Å; C219-C294 HydrophobicContact CB-CB 4Å; C219-C294 WeakPolarHBondContact CB-SG 3.31Å; C219-C294 VanDerWaalsContact O-CB 3.26Å; C219-C294 WeakPolarHBondContact O-CB 3.04Å; C219-C294 WeakPolarHBondContact SG-CB 3.16Å; C219-C294 CovalentContact SG-SG 2.01Å; C219-C294 PolarHBondContact SG-SG 3.28Å
220	L	95	Very high	91.5	Very high	48 Å²	48	41.7 Å²	41.7	25%	0.251	23%	0.226	S	C	.	.	H	α-helix	trans	-59.2	-44.5	177.1	-179.5	60.5	0	0	0	112.1	F214 N216 S217 S222 F223 L224 L280	F214-L220 HydrophobicContact CD1-CD1 4.16Å; N216-L220 PolarHBondContact O-N 3.46Å; S217-L220 PolarHBondContact O-N 2.82Å; L220-S222 PolarHBondContact O-N 3.41Å; L220-F223 HydrophobicContact CD1-CD1 4.11Å; L220-F223 WeakPolarHBondContact O-CB 3.45Å; L220-F223 PolarHBondContact O-N 3.42Å; L220-L224 HydrophobicContact CD1-CD1 4.31Å; L220-L224 HydrophobicContact CD1-CG 4.3Å; L220-L224 HydrophobicContact CG-CD1 4.15Å; L220-L224 WeakPolarHBondContact O-CG 3.36Å; L220-L224 PolarHBondContact O-N 3.21Å; L220-L280 HydrophobicContact CD1-CD2 3.91Å
221	A	95.6	Very high	91.8	Very high	42 Å²	42	43 Å²	43	35%	0.347	23%	0.234	S	C	.	.	H	α-helix	trans	-61.9	-43.5	176.6	0	0	0	0	0	111.9	S217 C219 F223 L224 L225	S217-A221 VanDerWaalsContact O-CB 3.24Å; S217-A221 WeakPolarHBondContact O-CB 3.3Å; S217-A221 PolarHBondContact O-N 3.16Å; C219-A221 VanDerWaalsContact C-N 3.35Å; C219-A221 PolarHBondContact O-N 2.87Å; A221-F223 VanDerWaalsContact C-N 3.32Å; A221-F223 PolarHBondContact O-N 3.13Å; A221-L224 PolarHBondContact O-N 3.26Å; A221-L225 VanDerWaalsContact O-CB 3.29Å; A221-L225 WeakPolarHBondContact O-CB 3.35Å; A221-L225 WeakPolarHBondContact O-CG 3.48Å; A221-L225 PolarHBondContact O-N 2.94Å
222	S	95.8	Very high	92.3	Very high	6 Å²	6	40.2 Å²	40.2	4%	0.042	22%	0.22	C	C	.	.	H	α-helix	trans	-61.5	-41.9	176.5	-61.3	0	0	0	0	111.6	Y218 C219 L220 N226 C294	Y218-S222 WeakPolarHBondContact O-CB 3.31Å; Y218-S222 PolarHBondContact O-N 3.44Å; Y218-S222 PolarHBondContact O-OG 3.44Å; C219-S222 PolarHBondContact O-N 3.4Å; L220-S222 PolarHBondContact O-N 3.41Å; S222-N226 WeakPolarHBondContact O-CB 3.49Å; S222-N226 PolarHBondContact O-N 3.24Å; S222-C294 CarbonylContact C-O 3.31Å
223	F	96.8	Very high	93.2	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-61.2	-51.2	174.4	159.3	-103.2	0	0	0	111.6	C219 L220 A221 N226 Y227 T276 V279 L280 V285 C294 V296	C219-F223 PolarHBondContact O-N 3.17Å; L220-F223 HydrophobicContact CD1-CD1 4.11Å; L220-F223 WeakPolarHBondContact O-CB 3.45Å; L220-F223 PolarHBondContact O-N 3.42Å; A221-F223 VanDerWaalsContact C-N 3.32Å; A221-F223 PolarHBondContact O-N 3.13Å; F223-N226 PolarHBondContact O-N 2.87Å; F223-Y227 HydrophobicContact CD2-CD1 4.48Å; F223-Y227 HydrophobicContact CD2-CG 4.22Å; F223-Y227 AromaticContact CE2-CD1 3.52Å; F223-Y227 HydrophobicContact CE2-CD1 3.52Å; F223-Y227 HydrophobicContact CE2-CE1 4.33Å; F223-Y227 AromaticContact CE2-CG 3.62Å; F223-Y227 HydrophobicContact CE2-CG 3.62Å; F223-Y227 AromaticContact CZ-CD1 3.87Å; F223-Y227 HydrophobicContact CZ-CD1 3.87Å; F223-Y227 HydrophobicContact CZ-CG 4.41Å; F223-Y227 VanDerWaalsContact O-CB 3.27Å; F223-Y227 WeakPolarHBondContact O-CB 3.47Å; F223-Y227 PolarHBondContact O-N 2.93Å; F223-T276 HydrophobicContact CE1-CG2 3.87Å; F223-T276 HydrophobicContact CZ-CG2 3.87Å; F223-V279 HydrophobicContact CE2-CG1 3.7Å; F223-V279 HydrophobicContact CZ-CB 4.16Å; F223-V279 HydrophobicContact CZ-CG1 3.61Å; F223-L280 HydrophobicContact CD1-CD2 4.2Å; F223-L280 HydrophobicContact CE1-CD1 4.39Å; F223-L280 HydrophobicContact CE1-CD2 3.59Å; F223-L280 HydrophobicContact CE1-CG 3.87Å; F223-L280 HydrophobicContact CZ-CD2 4.4Å; F223-L280 HydrophobicContact CZ-CG 4.39Å; F223-V285 HydrophobicContact CB-CG1 3.8Å; F223-V285 HydrophobicContact CD1-CG1 4.44Å; F223-V285 HydrophobicContact CD1-CG2 3.9Å; F223-V285 HydrophobicContact CD2-CG1 4.16Å; F223-V285 HydrophobicContact CD2-CG2 3.93Å; F223-V285 HydrophobicContact CE1-CG2 3.93Å; F223-V285 HydrophobicContact CE2-CG2 3.97Å; F223-V285 HydrophobicContact CG-CG1 3.86Å; F223-V285 HydrophobicContact CG-CG2 3.89Å; F223-V285 HydrophobicContact CZ-CG2 3.96Å; F223-C294 VanDerWaalsContact CA-O 3.23Å; F223-C294 WeakPolarHBondContact CA-O 3.01Å; F223-C294 HydrophobicContact CB-CB 4.31Å; F223-C294 PolarHBondContact N-O 2.83Å; F223-V296 HydrophobicContact CD2-CG2 4.13Å; F223-V296 HydrophobicContact CE2-CG2 3.57Å
224	L	97.1	Very high	94.5	Very high	68 Å²	68	39.2 Å²	39.2	36%	0.356	21%	0.212	S	C	.	.	I	π-helix	trans	-62.6	-46.8	-179.4	-69.6	173.2	0	0	0	111.4	L220 A221 N226 F228 T276	L220-L224 HydrophobicContact CD1-CD1 4.31Å; L220-L224 HydrophobicContact CD1-CG 4.3Å; L220-L224 HydrophobicContact CG-CD1 4.15Å; L220-L224 WeakPolarHBondContact O-CG 3.36Å; L220-L224 PolarHBondContact O-N 3.21Å; A221-L224 PolarHBondContact O-N 3.26Å; L224-N226 VanDerWaalsContact C-N 3.34Å; L224-N226 PolarHBondContact O-N 3.45Å; L224-F228 VanDerWaalsContact O-CB 3.29Å; L224-F228 WeakPolarHBondContact O-CB 3.49Å; L224-F228 PolarHBondContact O-N 2.9Å; L224-T276 HydrophobicContact CD2-CG2 3.8Å
225	L	97.3	Very high	95.4	Very high	56 Å²	56	35.6 Å²	35.6	29%	0.293	20%	0.197	S	C	.	.	I	π-helix	trans	-65.2	-38.2	179.7	-69.2	172.3	0	0	0	111.7	I181 S182 P185 A221 F229	I181-L225 HydrophobicContact CG2-CD2 3.54Å; S182-L225 VanDerWaalsContact CA-O 3.3Å; S182-L225 WeakPolarHBondContact CA-O 3.24Å; P185-L225 HydrophobicContact CG-CB 3.48Å; P185-L225 VanDerWaalsContact CG-CB 3.48Å; P185-L225 HydrophobicContact CG-CD1 4.29Å; A221-L225 VanDerWaalsContact O-CB 3.29Å; A221-L225 WeakPolarHBondContact O-CB 3.35Å; A221-L225 WeakPolarHBondContact O-CG 3.48Å; A221-L225 PolarHBondContact O-N 2.94Å; L225-F229 HydrophobicContact CD2-CE2 4.34Å; L225-F229 WeakPolarHBondContact O-CB 3.4Å; L225-F229 WeakPolarHBondContact O-CD2 3.25Å
226	N	96.1	Very high	96.1	Very high	23 Å²	23	30 Å²	30	12%	0.123	17%	0.167	C	C	.	.	I	π-helix	trans	-83.4	-60	-178.7	-175.1	-108.3	0	0	0	113	S182 P185 Y186 S222 F223 L224 S230 S295	S182-N226 PolarHBondContact O-ND2 3.4Å; P185-N226 HydrophobicContact CG-CB 4.17Å; Y186-N226 WeakPolarHBondContact CE2-ND2 3.22Å; S222-N226 WeakPolarHBondContact O-CB 3.49Å; S222-N226 PolarHBondContact O-N 3.24Å; F223-N226 PolarHBondContact O-N 2.87Å; L224-N226 VanDerWaalsContact C-N 3.34Å; L224-N226 PolarHBondContact O-N 3.45Å; N226-S230 WeakPolarHBondContact O-CB 3.11Å; N226-S230 PolarHBondContact O-N 2.76Å; N226-S230 PolarHBondContact O-OG 2.79Å; N226-S295 PolarHBondContact OD1-OG 2.92Å
227	Y	97.4	Very high	96.5	Very high	9 Å²	9	29.4 Å²	29.4	4%	0.035	16%	0.163	C	C	.	.	I	π-helix	trans	-70.1	-48.3	-169.8	179	-98.2	0	0	0	112.7	F223 S230 T231 V279 V296 F307 V308	F223-Y227 HydrophobicContact CD2-CD1 4.48Å; F223-Y227 HydrophobicContact CD2-CG 4.22Å; F223-Y227 AromaticContact CE2-CD1 3.52Å; F223-Y227 HydrophobicContact CE2-CD1 3.52Å; F223-Y227 HydrophobicContact CE2-CE1 4.33Å; F223-Y227 AromaticContact CE2-CG 3.62Å; F223-Y227 HydrophobicContact CE2-CG 3.62Å; F223-Y227 AromaticContact CZ-CD1 3.87Å; F223-Y227 HydrophobicContact CZ-CD1 3.87Å; F223-Y227 HydrophobicContact CZ-CG 4.41Å; F223-Y227 VanDerWaalsContact O-CB 3.27Å; F223-Y227 WeakPolarHBondContact O-CB 3.47Å; F223-Y227 PolarHBondContact O-N 2.93Å; Y227-S230 PolarHBondContact O-OG 2.94Å; Y227-T231 VanDerWaalsContact O-CB 3.29Å; Y227-T231 WeakPolarHBondContact O-CB 3.43Å; Y227-T231 PolarHBondContact O-N 2.98Å; Y227-T231 PolarHBondContact O-OG1 3.32Å; Y227-V279 HydrophobicContact CE1-CG2 3.99Å; Y227-V296 HydrophobicContact CD1-CG2 4.49Å; Y227-V296 HydrophobicContact CD2-CB 4.31Å; Y227-V296 HydrophobicContact CD2-CG2 3.79Å; Y227-V296 HydrophobicContact CE2-CB 4.22Å; Y227-V296 HydrophobicContact CE2-CG2 3.84Å; Y227-V296 HydrophobicContact CG-CG2 4.13Å; Y227-F307 PolarHBondContact OH-O 2.05Å; Y227-V308 HydrophobicContact CE2-CG2 4.35Å
228	F	97.9	Very high	96.7	Very high	36 Å²	36	26.8 Å²	26.8	16%	0.158	14%	0.143	C	C	.	.	I	π-helix	trans	-63.2	-49	-179.5	169.1	-96.7	0	0	0	111.1	L224 T231 A232 W269 S273 T276	L224-F228 VanDerWaalsContact O-CB 3.29Å; L224-F228 WeakPolarHBondContact O-CB 3.49Å; L224-F228 PolarHBondContact O-N 2.9Å; F228-T231 PolarHBondContact O-N 3.15Å; F228-A232 WeakPolarHBondContact O-CB 3.37Å; F228-A232 PolarHBondContact O-N 2.9Å; F228-W269 HydrophobicContact CE1-CE3 4.41Å; F228-W269 HydrophobicContact CE1-CZ3 4.27Å; F228-W269 HydrophobicContact CZ-CE3 4.02Å; F228-W269 HydrophobicContact CZ-CZ3 4.34Å; F228-S273 WeakPolarHBondContact CE2-OG 3.4Å; F228-T276 HydrophobicContact CB-CG2 4.44Å; F228-T276 WeakPolarHBondContact CB-OG1 3.49Å
229	F	98.3	Very high	96.9	Very high	39 Å²	39	22.1 Å²	22.1	17%	0.171	13%	0.126	C	C	.	.	H	α-helix	trans	-74.3	-31.6	-176.6	-69.8	-82	0	0	0	113.3	C178 I181 L225 A232 A233	C178-F229 HydrophobicContact CB-CB 4.5Å; C178-F229 WeakPolarHBondContact CB-O 3.31Å; I181-F229 HydrophobicContact CB-CB 4.44Å; I181-F229 HydrophobicContact CB-CD1 4.01Å; I181-F229 HydrophobicContact CB-CD2 4.13Å; I181-F229 HydrophobicContact CB-CE1 4.27Å; I181-F229 HydrophobicContact CB-CE2 4.39Å; I181-F229 HydrophobicContact CB-CG 3.92Å; I181-F229 HydrophobicContact CB-CZ 4.44Å; I181-F229 HydrophobicContact CD1-CD1 3.92Å; I181-F229 HydrophobicContact CD1-CE1 3.44Å; I181-F229 VanDerWaalsContact CD1-CE1 3.44Å; I181-F229 HydrophobicContact CD1-CZ 3.78Å; I181-F229 HydrophobicContact CG1-CE1 4.45Å; I181-F229 HydrophobicContact CG2-CB 4.48Å; I181-F229 HydrophobicContact CG2-CD1 4.09Å; I181-F229 HydrophobicContact CG2-CD2 3.38Å; I181-F229 HydrophobicContact CG2-CE1 4.13Å; I181-F229 HydrophobicContact CG2-CE2 3.44Å; I181-F229 VanDerWaalsContact CG2-CE2 3.44Å; I181-F229 HydrophobicContact CG2-CG 3.72Å; I181-F229 HydrophobicContact CG2-CZ 3.81Å; L225-F229 HydrophobicContact CD2-CE2 4.34Å; L225-F229 WeakPolarHBondContact O-CB 3.4Å; L225-F229 WeakPolarHBondContact O-CD2 3.25Å; F229-A232 PolarHBondContact O-N 3.37Å; F229-A233 WeakPolarHBondContact O-CB 3.41Å; F229-A233 PolarHBondContact O-N 3.46Å
230	S	96.8	Very high	96.9	Very high	30 Å²	30	22 Å²	22	21%	0.21	13%	0.125	C	C	.	.	H	α-helix	trans	-68	-37.8	171.7	60.1	0	0	0	0	112	N226 Y227 A233 A234	N226-S230 WeakPolarHBondContact O-CB 3.11Å; N226-S230 PolarHBondContact O-N 2.76Å; N226-S230 PolarHBondContact O-OG 2.79Å; Y227-S230 PolarHBondContact O-OG 2.94Å; S230-A233 WeakPolarHBondContact O-CB 3.33Å; S230-A233 PolarHBondContact O-N 3.18Å; S230-A234 PolarHBondContact O-N 2.81Å
231	T	97.6	Very high	96.9	Very high	29 Å²	29	19.8 Å²	19.8	18%	0.178	11%	0.113	C	C	.	.	H	α-helix	trans	-64.4	-43.9	172.6	-56.8	0	0	0	0	111.1	Y227 F228 A233 A234 L235	Y227-T231 VanDerWaalsContact O-CB 3.29Å; Y227-T231 WeakPolarHBondContact O-CB 3.43Å; Y227-T231 PolarHBondContact O-N 2.98Å; Y227-T231 PolarHBondContact O-OG1 3.32Å; F228-T231 PolarHBondContact O-N 3.15Å; T231-A233 VanDerWaalsContact C-N 3.34Å; T231-A233 PolarHBondContact O-N 3.45Å; T231-A234 PolarHBondContact O-N 2.88Å; T231-L235 HydrophobicContact CG2-CD1 4.3Å; T231-L235 PolarHBondContact O-N 3.04Å
232	A	98.1	Very high	96.9	Very high	0 Å²	0	21 Å²	21	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-62.9	-39.6	175	0	0	0	0	0	112.2	F228 F229 A234 L235 W236 W269 S272	F228-A232 WeakPolarHBondContact O-CB 3.37Å; F228-A232 PolarHBondContact O-N 2.9Å; F229-A232 PolarHBondContact O-N 3.37Å; A232-A234 PolarHBondContact O-N 3.32Å; A232-L235 PolarHBondContact O-N 3.49Å; A232-W236 WeakPolarHBondContact O-CB 3.45Å; A232-W236 PolarHBondContact O-N 3.19Å; A232-W269 HydrophobicContact CB-CE3 3.9Å; A232-W269 HydrophobicContact CB-CZ3 3.55Å; A232-S272 WeakPolarHBondContact CA-OG 3.41Å; A232-S272 WeakPolarHBondContact CB-OG 3.22Å; A232-S272 PolarHBondContact N-OG 3.41Å
233	A	97.6	Very high	96.9	Very high	8 Å²	8	20.7 Å²	20.7	7%	0.066	11%	0.109	C	C	.	.	H	α-helix	trans	-59.7	-45.8	174.2	0	0	0	0	0	111.4	L175 C178 I179 F229 S230 T231 L235 W236 W237	L175-A233 HydrophobicContact CD1-CB 3.76Å; L175-A233 WeakPolarHBondContact CD1-O 3.27Å; C178-A233 HydrophobicContact CB-CB 3.78Å; I179-A233 HydrophobicContact CG1-CB 4.25Å; F229-A233 WeakPolarHBondContact O-CB 3.41Å; F229-A233 PolarHBondContact O-N 3.46Å; S230-A233 WeakPolarHBondContact O-CB 3.33Å; S230-A233 PolarHBondContact O-N 3.18Å; T231-A233 VanDerWaalsContact C-N 3.34Å; T231-A233 PolarHBondContact O-N 3.45Å; A233-L235 VanDerWaalsContact C-N 3.34Å; A233-L235 PolarHBondContact O-N 2.96Å; A233-W236 PolarHBondContact O-N 3.42Å; A233-W237 PolarHBondContact O-N 3.16Å
234	A	96.9	Very high	96.7	Very high	14 Å²	14	21 Å²	21	12%	0.116	11%	0.11	C	C	.	.	H	α-helix	trans	-60.8	-42.2	176.7	0	0	0	0	0	112.2	S230 T231 A232 W237 L238	S230-A234 PolarHBondContact O-N 2.81Å; T231-A234 PolarHBondContact O-N 2.88Å; A232-A234 PolarHBondContact O-N 3.32Å; A234-W237 PolarHBondContact O-N 3.11Å; A234-L238 PolarHBondContact O-N 3.49Å
235	L	97.7	Very high	96.6	Very high	12 Å²	12	20.3 Å²	20.3	6%	0.063	10%	0.103	C	C	.	.	H	α-helix	trans	-71.9	-35.5	177.7	-72.1	168.7	0	0	0	113	T231 A232 A233 W237 L238 M239 A268 L271 S272	T231-L235 HydrophobicContact CG2-CD1 4.3Å; T231-L235 PolarHBondContact O-N 3.04Å; A232-L235 PolarHBondContact O-N 3.49Å; A233-L235 VanDerWaalsContact C-N 3.34Å; A233-L235 PolarHBondContact O-N 2.96Å; L235-W237 VanDerWaalsContact C-N 3.29Å; L235-W237 PolarHBondContact O-N 2.91Å; L235-L238 HydrophobicContact CD2-CD2 4.19Å; L235-L238 WeakPolarHBondContact O-CB 3.29Å; L235-L238 PolarHBondContact O-N 2.95Å; L235-M239 WeakPolarHBondContact O-CG 3.49Å; L235-M239 PolarHBondContact O-N 3.39Å; L235-A268 HydrophobicContact CB-CB 4.3Å; L235-L271 HydrophobicContact CD1-CB 3.69Å; L235-L271 HydrophobicContact CD2-CD1 4.36Å; L235-S272 VanDerWaalsContact CD1-OG 3.31Å; L235-S272 WeakPolarHBondContact CD1-OG 3.2Å
236	W	97.6	Very high	96.4	Very high	1 Å²	1	18.6 Å²	18.6	0%	0.004	9%	0.094	C	C	.	.	H	α-helix	trans	-64.1	-36.7	172.3	-86.3	116.3	0	0	0	112.1	C171 Y174 L175 A232 A233 M239 F240 V264 H265 A268 W269	C171-W236 HydrophobicContact CB-CE3 4.2Å; Y174-W236 VanDerWaalsContact CB-CE2 3.45Å; Y174-W236 HydrophobicContact CD1-CZ2 4.45Å; Y174-W236 HydrophobicContact CD2-CE3 4.35Å; Y174-W236 AromaticContact CD2-CH2 3.71Å; Y174-W236 HydrophobicContact CD2-CH2 3.71Å; Y174-W236 AromaticContact CD2-CZ2 3.95Å; Y174-W236 HydrophobicContact CD2-CZ2 3.95Å; Y174-W236 AromaticContact CD2-CZ3 3.91Å; Y174-W236 HydrophobicContact CD2-CZ3 3.91Å; Y174-W236 HydrophobicContact CE2-CH2 4.29Å; Y174-W236 HydrophobicContact CG-CD2 4.41Å; Y174-W236 AromaticContact CG-CE2 3.98Å; Y174-W236 HydrophobicContact CG-CH2 4.08Å; Y174-W236 AromaticContact CG-CZ2 3.82Å; Y174-W236 HydrophobicContact CG-CZ2 3.82Å; Y174-W236 HydrophobicContact CG-CZ3 4.45Å; L175-W236 HydrophobicContact CB-CB 4.27Å; L175-W236 HydrophobicContact CD1-CB 4.31Å; A232-W236 WeakPolarHBondContact O-CB 3.45Å; A232-W236 PolarHBondContact O-N 3.19Å; A233-W236 PolarHBondContact O-N 3.42Å; W236-M239 HydrophobicContact CE3-CB 4.37Å; W236-M239 PolarHBondContact O-N 2.8Å; W236-F240 WeakPolarHBondContact O-CB 3.4Å; W236-F240 PolarHBondContact O-N 2.89Å; W236-V264 HydrophobicContact CH2-CG1 4.3Å; W236-V264 HydrophobicContact CZ3-CG1 3.78Å; W236-H265 AromaticContact CH2-CE1 3.42Å; W236-H265 VanDerWaalsContact CH2-CE1 3.42Å; W236-H265 WeakPolarHBondContact CH2-CE1 3.42Å; W236-H265 AromaticContact CH2-CG 3.97Å; W236-H265 AromaticContact CH2-ND1 3.35Å; W236-H265 VanDerWaalsContact CH2-ND1 3.35Å; W236-H265 WeakPolarHBondContact CH2-ND1 3.34Å; W236-H265 AromaticContact CZ2-CE1 3.81Å; W236-H265 AromaticContact CZ2-ND1 3.51Å; W236-A268 HydrophobicContact CD2-CB 3.73Å; W236-A268 HydrophobicContact CE3-CB 4.2Å; W236-A268 HydrophobicContact CG-CB 4.11Å; W236-A268 HydrophobicContact CH2-CB 4.25Å; W236-A268 HydrophobicContact CZ2-CB 3.8Å; W236-A268 HydrophobicContact CZ3-CB 4.45Å; W236-W269 AromaticContact CE2-CE2 3.87Å; W236-W269 AromaticContact CE2-CZ2 3.91Å; W236-W269 HydrophobicContact CZ2-CD2 4.45Å; W236-W269 AromaticContact CZ2-CE2 3.74Å; W236-W269 HydrophobicContact CZ2-CZ2 4.08Å; W236-W269 AromaticContact CZ2-NE1 3.49Å; W236-W269 AromaticContact NE1-CD2 3.81Å; W236-W269 AromaticContact NE1-CE2 3.4Å; W236-W269 AromaticContact NE1-CH2 3.47Å; W236-W269 AromaticContact NE1-CZ2 3.22Å; W236-W269 AromaticContact NE1-CZ3 3.86Å
237	W	96.8	Very high	96.1	Very high	4 Å²	4	19.5 Å²	19.5	2%	0.015	10%	0.102	C	C	.	.	H	α-helix	trans	-68	-39.1	172	177.7	85.3	0	0	0	112.6	L175 A233 A234 L235 M239 F240 S241 C315 I323 F361 I362	L175-W237 HydrophobicContact CD1-CB 4.45Å; A233-W237 PolarHBondContact O-N 3.16Å; A234-W237 PolarHBondContact O-N 3.11Å; L235-W237 VanDerWaalsContact C-N 3.29Å; L235-W237 PolarHBondContact O-N 2.91Å; W237-M239 VanDerWaalsContact C-N 3.32Å; W237-M239 PolarHBondContact O-N 2.94Å; W237-F240 WeakPolarHBondContact O-CB 3.32Å; W237-F240 PolarHBondContact O-N 3.44Å; W237-S241 PolarHBondContact O-N 3.01Å; W237-S241 PolarHBondContact O-OG 3.41Å; W237-C315 WeakPolarHBondContact CZ3-O 3.13Å; W237-I323 HydrophobicContact CH2-CD1 4.03Å; W237-I323 HydrophobicContact CZ2-CD1 3.33Å; W237-F361 HydrophobicContact CB-CD1 4.28Å; W237-F361 HydrophobicContact CB-CE1 3.57Å; W237-F361 HydrophobicContact CB-CE2 4.31Å; W237-F361 HydrophobicContact CB-CZ 3.58Å; W237-F361 AromaticContact CD1-CD1 3.15Å; W237-F361 AromaticContact CD1-CE1 3.38Å; W237-F361 AromaticContact CD1-CG 3.48Å; W237-F361 VanDerWaalsContact CD1-CG 3.48Å; W237-F361 AromaticContact CD1-CZ 3.91Å; W237-F361 AromaticContact CD2-CD1 3.69Å; W237-F361 HydrophobicContact CD2-CD1 3.69Å; W237-F361 AromaticContact CD2-CE1 3.52Å; W237-F361 HydrophobicContact CD2-CE1 3.52Å; W237-F361 HydrophobicContact CD2-CZ 4.45Å; W237-F361 AromaticContact CE2-CD1 3.54Å; W237-F361 AromaticContact CE2-CE1 3.91Å; W237-F361 HydrophobicContact CE3-CE1 4.22Å; W237-F361 AromaticContact CG-CD1 3.45Å; W237-F361 HydrophobicContact CG-CD1 3.45Å; W237-F361 VanDerWaalsContact CG-CD1 3.45Å; W237-F361 AromaticContact CG-CE1 3.17Å; W237-F361 HydrophobicContact CG-CE1 3.17Å; W237-F361 HydrophobicContact CG-CE2 4.38Å; W237-F361 HydrophobicContact CG-CG 4.16Å; W237-F361 AromaticContact CG-CZ 3.69Å; W237-F361 HydrophobicContact CG-CZ 3.69Å; W237-F361 HydrophobicContact CZ2-CD1 4.34Å; W237-F361 AromaticContact NE1-CD1 3.19Å; W237-F361 AromaticContact NE1-CE1 3.8Å; W237-F361 AromaticContact NE1-CG 3.65Å; W237-I362 HydrophobicContact CH2-CD1 4.43Å; W237-I362 HydrophobicContact CH2-CG1 4.06Å; W237-I362 HydrophobicContact CZ2-CD1 3.88Å; W237-I362 HydrophobicContact CZ2-CG1 3.46Å; W237-I362 VanDerWaalsContact CZ2-CG1 3.46Å
238	L	97.1	Very high	95.6	Very high	23 Å²	23	19.6 Å²	19.6	12%	0.12	11%	0.106	C	C	.	.	H	α-helix	trans	-60.3	-43.7	171.7	176.8	62.3	0	0	0	111	A234 L235 S241 F242 I318 F322	A234-L238 PolarHBondContact O-N 3.49Å; L235-L238 HydrophobicContact CD2-CD2 4.19Å; L235-L238 WeakPolarHBondContact O-CB 3.29Å; L235-L238 PolarHBondContact O-N 2.95Å; L238-S241 WeakPolarHBondContact O-CB 3.45Å; L238-S241 PolarHBondContact O-N 3.27Å; L238-F242 WeakPolarHBondContact O-CB 3.34Å; L238-F242 PolarHBondContact O-N 3.15Å; L238-I318 HydrophobicContact CD1-CB 4.07Å; L238-I318 HydrophobicContact CD1-CG2 3.76Å; L238-F322 HydrophobicContact CD1-CD2 4.24Å; L238-F322 HydrophobicContact CD1-CE2 4.36Å
239	M	96.6	Very high	95	Very high	14 Å²	14	19 Å²	19	7%	0.069	11%	0.11	C	C	.	.	H	α-helix	trans	-66.5	-37.2	176.5	-72.4	-40.5	-52.8	0	0	113.1	L235 W236 W237 S241 F242 T243 V264 V267 A268	L235-M239 WeakPolarHBondContact O-CG 3.49Å; L235-M239 PolarHBondContact O-N 3.39Å; W236-M239 HydrophobicContact CE3-CB 4.37Å; W236-M239 PolarHBondContact O-N 2.8Å; W237-M239 VanDerWaalsContact C-N 3.32Å; W237-M239 PolarHBondContact O-N 2.94Å; M239-S241 VanDerWaalsContact C-N 3.32Å; M239-F242 HydrophobicContact CE-CB 4.33Å; M239-F242 HydrophobicContact CE-CD1 3.54Å; M239-F242 HydrophobicContact CE-CE1 4.24Å; M239-F242 HydrophobicContact CE-CG 4.26Å; M239-F242 PolarHBondContact O-N 3.46Å; M239-T243 WeakPolarHBondContact O-CB 3.31Å; M239-T243 WeakPolarHBondContact O-CG2 3.08Å; M239-T243 PolarHBondContact O-N 3.48Å; M239-T243 PolarHBondContact O-OG1 3.3Å; M239-V264 HydrophobicContact CB-CG1 3.81Å; M239-V264 HydrophobicContact CE-CB 4.07Å; M239-V264 HydrophobicContact CE-CG1 3.76Å; M239-V264 HydrophobicContact CE-CG2 3.9Å; M239-V264 HydrophobicContact CG-CG1 3.86Å; M239-V267 HydrophobicContact SD-CB 4.11Å; M239-V267 HydrophobicContact SD-CG1 3.8Å; M239-A268 HydrophobicContact CG-CB 4.25Å
240	F	95.2	Very high	94.5	Very high	1 Å²	1	24.6 Å²	24.6	0%	0.004	13%	0.13	C	C	.	.	H	α-helix	trans	-57.9	-47.3	169.2	167.4	-92.5	0	0	0	110.7	P168 C171 V172 W236 W237 F242 T243 L244 M354 F357	P168-F240 HydrophobicContact CB-CD2 4.12Å; P168-F240 HydrophobicContact CB-CE2 4.26Å; P168-F240 HydrophobicContact CG-CE2 4.48Å; C171-F240 HydrophobicContact CB-CB 3.73Å; C171-F240 HydrophobicContact CB-CD2 4.38Å; V172-F240 HydrophobicContact CG2-CD2 4.05Å; V172-F240 HydrophobicContact CG2-CE2 4.19Å; W236-F240 WeakPolarHBondContact O-CB 3.4Å; W236-F240 PolarHBondContact O-N 2.89Å; W237-F240 WeakPolarHBondContact O-CB 3.32Å; W237-F240 PolarHBondContact O-N 3.44Å; F240-F242 PolarHBondContact O-N 3.24Å; F240-T243 PolarHBondContact O-N 3.35Å; F240-T243 PolarHBondContact O-OG1 3.45Å; F240-T243 VanDerWaalsContact O-OG1 3.06Å; F240-L244 HydrophobicContact CE1-CD2 4.23Å; F240-L244 HydrophobicContact CZ-CD2 4.4Å; F240-L244 VanDerWaalsContact O-CB 3.28Å; F240-L244 WeakPolarHBondContact O-CB 3.31Å; F240-L244 PolarHBondContact O-N 3.4Å; F240-M354 HydrophobicContact CE2-CE 4.49Å; F240-M354 HydrophobicContact CE2-SD 3.79Å; F240-M354 HydrophobicContact CZ-SD 3.55Å; F240-M354 VanDerWaalsContact CZ-SD 3.55Å; F240-F357 HydrophobicContact CD1-CD1 4.41Å; F240-F357 AromaticContact CD1-CE1 3.78Å; F240-F357 HydrophobicContact CD1-CE1 3.78Å; F240-F357 HydrophobicContact CD2-CE1 4.32Å; F240-F357 AromaticContact CE1-CD1 3.69Å; F240-F357 HydrophobicContact CE1-CD1 3.69Å; F240-F357 AromaticContact CE1-CE1 3.51Å; F240-F357 HydrophobicContact CE1-CE1 3.51Å; F240-F357 HydrophobicContact CE2-CD1 4.31Å; F240-F357 HydrophobicContact CE2-CE1 4.07Å; F240-F357 HydrophobicContact CG-CE1 4.18Å; F240-F357 AromaticContact CZ-CD1 3.62Å; F240-F357 HydrophobicContact CZ-CD1 3.62Å; F240-F357 AromaticContact CZ-CE1 3.66Å; F240-F357 HydrophobicContact CZ-CE1 3.66Å
241	S	95.8	Very high	94.1	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-62.2	-44.6	179.7	-57	0	0	0	0	111.8	W237 L238 M239 L244 Y245 G319 F322 I323	W237-S241 PolarHBondContact O-N 3.01Å; W237-S241 PolarHBondContact O-OG 3.41Å; L238-S241 WeakPolarHBondContact O-CB 3.45Å; L238-S241 PolarHBondContact O-N 3.27Å; M239-S241 VanDerWaalsContact C-N 3.32Å; S241-L244 WeakPolarHBondContact O-CB 3.36Å; S241-L244 PolarHBondContact O-N 3.23Å; S241-Y245 PolarHBondContact O-N 3Å; S241-G319 WeakPolarHBondContact CB-O 3.19Å; S241-F322 WeakPolarHBondContact O-CB 3.34Å; S241-I323 WeakPolarHBondContact OG-CD1 3.42Å
242	F	95.6	Very high	93.7	Very high	68 Å²	68	32.9 Å²	32.9	30%	0.298	16%	0.157	S	C	.	.	H	α-helix	trans	-62	-47.9	176.1	174.9	-108.3	0	0	0	112.3	L238 M239 F240 L244 Y245 L246 F322	L238-F242 WeakPolarHBondContact O-CB 3.34Å; L238-F242 PolarHBondContact O-N 3.15Å; M239-F242 HydrophobicContact CE-CB 4.33Å; M239-F242 HydrophobicContact CE-CD1 3.54Å; M239-F242 HydrophobicContact CE-CE1 4.24Å; M239-F242 HydrophobicContact CE-CG 4.26Å; M239-F242 PolarHBondContact O-N 3.46Å; F240-F242 PolarHBondContact O-N 3.24Å; F242-L244 VanDerWaalsContact C-N 3.32Å; F242-L244 PolarHBondContact O-N 3.09Å; F242-Y245 WeakPolarHBondContact O-CB 3.21Å; F242-Y245 PolarHBondContact O-N 2.93Å; F242-L246 HydrophobicContact CD1-CD1 4.08Å; F242-L246 HydrophobicContact CD1-CG 4.48Å; F242-L246 HydrophobicContact CE1-CD1 3.44Å; F242-L246 VanDerWaalsContact CE1-CD1 3.44Å; F242-L246 HydrophobicContact CE1-CG 4.1Å; F242-L246 HydrophobicContact CE2-CD1 4.38Å; F242-L246 HydrophobicContact CE2-CD2 4.28Å; F242-L246 HydrophobicContact CE2-CG 4.25Å; F242-L246 HydrophobicContact CZ-CD1 3.63Å; F242-L246 HydrophobicContact CZ-CD2 4.14Å; F242-L246 HydrophobicContact CZ-CG 3.98Å; F242-L246 WeakPolarHBondContact O-CG 3.35Å; F242-L246 PolarHBondContact O-N 2.95Å; F242-F322 HydrophobicContact CB-CD2 4.09Å; F242-F322 HydrophobicContact CB-CE2 4.17Å; F242-F322 HydrophobicContact CD2-CD2 4.44Å; F242-F322 HydrophobicContact CD2-CE1 4.06Å; F242-F322 AromaticContact CD2-CE2 3.94Å; F242-F322 HydrophobicContact CD2-CE2 3.94Å; F242-F322 AromaticContact CD2-CZ 3.75Å; F242-F322 HydrophobicContact CD2-CZ 3.75Å; F242-F322 HydrophobicContact CE2-CZ 4.43Å
243	T	94.4	Very high	93.2	Very high	0 Å²	0	37.4 Å²	37.4	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-68.6	-31.4	179.4	52	0	0	0	0	112.4	F167 P168 M239 F240 L246 S247 I257	F167-T243 HydrophobicContact CD1-CG2 4.39Å; P168-T243 VanDerWaalsContact CB-OG1 3.23Å; P168-T243 WeakPolarHBondContact CB-OG1 3.14Å; M239-T243 WeakPolarHBondContact O-CB 3.31Å; M239-T243 WeakPolarHBondContact O-CG2 3.08Å; M239-T243 PolarHBondContact O-N 3.48Å; M239-T243 PolarHBondContact O-OG1 3.3Å; F240-T243 PolarHBondContact O-N 3.35Å; F240-T243 PolarHBondContact O-OG1 3.45Å; F240-T243 VanDerWaalsContact O-OG1 3.06Å; T243-L246 PolarHBondContact O-N 3.02Å; T243-S247 WeakPolarHBondContact O-CB 3.34Å; T243-S247 PolarHBondContact O-N 3.19Å; T243-I257 HydrophobicContact CG2-CG2 3.83Å
244	L	93	Very high	92.7	Very high	5 Å²	5	38.7 Å²	38.7	3%	0.026	19%	0.192	C	C	.	.	H	α-helix	trans	-62.8	-44	169.5	-178.7	65	0	0	0	111.5	P168 F240 S241 F242 S247 G248 F327 M330 M354	P168-L244 HydrophobicContact CG-CD1 4.46Å; F240-L244 HydrophobicContact CE1-CD2 4.23Å; F240-L244 HydrophobicContact CZ-CD2 4.4Å; F240-L244 VanDerWaalsContact O-CB 3.28Å; F240-L244 WeakPolarHBondContact O-CB 3.31Å; F240-L244 PolarHBondContact O-N 3.4Å; S241-L244 WeakPolarHBondContact O-CB 3.36Å; S241-L244 PolarHBondContact O-N 3.23Å; F242-L244 VanDerWaalsContact C-N 3.32Å; F242-L244 PolarHBondContact O-N 3.09Å; L244-S247 PolarHBondContact O-N 2.75Å; L244-G248 PolarHBondContact O-N 2.67Å; L244-F327 HydrophobicContact CD2-CD2 4.45Å; L244-F327 HydrophobicContact CD2-CE2 3.94Å; L244-M330 HydrophobicContact CD1-CE 3.95Å; L244-M330 HydrophobicContact CD1-SD 4.33Å; L244-M330 HydrophobicContact CG-CE 4.45Å; L244-M354 HydrophobicContact CD1-CG 4.5Å
245	Y	94.5	Very high	92.3	Very high	54 Å²	54	42.4 Å²	42.4	21%	0.212	21%	0.207	C	C	.	.	H	α-helix	trans	-62.9	-42.4	173.9	170.6	-105.7	0	0	0	112.4	S241 F242 S247 G249 R250 F322	S241-Y245 PolarHBondContact O-N 3Å; F242-Y245 WeakPolarHBondContact O-CB 3.21Å; F242-Y245 PolarHBondContact O-N 2.93Å; Y245-S247 PolarHBondContact O-N 3.41Å; Y245-G249 VanDerWaalsContact O-CA 3.28Å; Y245-G249 WeakPolarHBondContact O-CA 3.49Å; Y245-G249 PolarHBondContact O-N 3.45Å; Y245-R250 HydrophobicContact CE1-CG 4.03Å; Y245-R250 PolarHBondContact O-N 3.23Å; Y245-R250 PolarHBondContact OH-NE 3.46Å; Y245-R250 PolarHBondContact OH-NH2 3.24Å; Y245-F322 AromaticContact CD1-CD1 3.95Å; Y245-F322 HydrophobicContact CD1-CD1 3.95Å; Y245-F322 HydrophobicContact CD1-CE1 4.28Å; Y245-F322 AromaticContact CG-CD1 3.99Å; Y245-F322 HydrophobicContact CG-CD1 3.99Å
246	L	93.3	Very high	91.8	Very high	20 Å²	20	43.2 Å²	43.2	11%	0.105	22%	0.219	C	C	.	.	H	α-helix	trans	-62.6	-44.2	176.9	-70.3	-175.4	0	0	0	111.9	F242 T243 R250 K251 W252 I257	F242-L246 HydrophobicContact CD1-CD1 4.08Å; F242-L246 HydrophobicContact CD1-CG 4.48Å; F242-L246 HydrophobicContact CE1-CD1 3.44Å; F242-L246 VanDerWaalsContact CE1-CD1 3.44Å; F242-L246 HydrophobicContact CE1-CG 4.1Å; F242-L246 HydrophobicContact CE2-CD1 4.38Å; F242-L246 HydrophobicContact CE2-CD2 4.28Å; F242-L246 HydrophobicContact CE2-CG 4.25Å; F242-L246 HydrophobicContact CZ-CD1 3.63Å; F242-L246 HydrophobicContact CZ-CD2 4.14Å; F242-L246 HydrophobicContact CZ-CG 3.98Å; F242-L246 WeakPolarHBondContact O-CG 3.35Å; F242-L246 PolarHBondContact O-N 2.95Å; T243-L246 PolarHBondContact O-N 3.02Å; L246-R250 HydrophobicContact CD2-CB 4.28Å; L246-R250 HydrophobicContact CD2-CG 4.02Å; L246-R250 CarbonylContact O-C 3.56Å; L246-R250 VanDerWaalsContact O-C 3.31Å; L246-R250 WeakPolarHBondContact O-CA 3.35Å; L246-R250 WeakPolarHBondContact O-CB 3.37Å; L246-R250 PolarHBondContact O-N 3.43Å; L246-R250 VanDerWaalsContact O-N 3.14Å; L246-K251 PolarHBondContact O-N 2.78Å; L246-W252 HydrophobicContact CB-CB 4.23Å; L246-W252 HydrophobicContact CB-CG 4.19Å; L246-W252 HydrophobicContact CD1-CD2 4.49Å; L246-W252 PolarHBondContact O-N 3.24Å; L246-I257 HydrophobicContact CB-CD1 4.41Å
247	S	89.8	Confident	91.4	Very high	43 Å²	43	43.4 Å²	43.4	30%	0.301	22%	0.219	S	C	.	.	H	α-helix	trans	-65.3	-50.1	178.9	-175.1	0	0	0	0	111.7	T243 L244 Y245 K251	T243-S247 WeakPolarHBondContact O-CB 3.34Å; T243-S247 PolarHBondContact O-N 3.19Å; L244-S247 PolarHBondContact O-N 2.75Å; Y245-S247 PolarHBondContact O-N 3.41Å; S247-K251 WeakPolarHBondContact O-CA 3.43Å; S247-K251 PolarHBondContact O-N 2.85Å
248	G	86.4	Confident	91	Very high	10 Å²	10	46.9 Å²	46.9	10%	0.103	24%	0.236	C	C	.	.	H	α-helix	trans	-78.6	-46.6	-177	0	0	0	0	0	114.5	L244 S329	L244-G248 PolarHBondContact O-N 2.67Å; G248-S329 VanDerWaalsContact O-CB 3.27Å; G248-S329 WeakPolarHBondContact O-CB 3.22Å
249	G	86	Confident	90.7	Very high	25 Å²	25	49.9 Å²	49.9	26%	0.258	26%	0.264	S	S	.	.	H	α-helix	trans	-91.6	-34.3	-172.2	0	0	0	0	0	115.1	Y245 S329	Y245-G249 VanDerWaalsContact O-CA 3.28Å; Y245-G249 WeakPolarHBondContact O-CA 3.49Å; Y245-G249 PolarHBondContact O-N 3.45Å; G249-S329 WeakPolarHBondContact CA-OG 3.16Å
250	R	88.3	Confident	90.4	Very high	155 Å²	155	51.5 Å²	51.5	59%	0.585	28%	0.276	S	S	*	.	S	Bend	trans	-102.9	-0	177.9	-58.1	-60.6	-173.8	112.3	-0.7	113.2	Y245 L246 W252	Y245-R250 HydrophobicContact CE1-CG 4.03Å; Y245-R250 PolarHBondContact O-N 3.23Å; Y245-R250 PolarHBondContact OH-NE 3.46Å; Y245-R250 PolarHBondContact OH-NH2 3.24Å; L246-R250 HydrophobicContact CD2-CB 4.28Å; L246-R250 HydrophobicContact CD2-CG 4.02Å; L246-R250 CarbonylContact O-C 3.56Å; L246-R250 VanDerWaalsContact O-C 3.31Å; L246-R250 WeakPolarHBondContact O-CA 3.35Å; L246-R250 WeakPolarHBondContact O-CB 3.37Å; L246-R250 PolarHBondContact O-N 3.43Å; L246-R250 VanDerWaalsContact O-N 3.14Å; R250-W252 VanDerWaalsContact CB-CD1 3.45Å; R250-W252 PolarHBondContact O-N 2.86Å
251	K	87.4	Confident	90.2	Very high	128 Å²	128	52.6 Å²	52.6	56%	0.557	28%	0.284	S	S	*	.			trans	56.8	33.3	179.5	-52.9	-171.8	-178.3	-160.1	0	113.2	L246 S247 V253 E333	L246-K251 PolarHBondContact O-N 2.78Å; S247-K251 WeakPolarHBondContact O-CA 3.43Å; S247-K251 PolarHBondContact O-N 2.85Å; K251-V253 PolarHBondContact O-N 2.8Å; K251-E333 WeakPolarHBondContact CE-OE1 3.5Å; K251-E333 IonicContact NZ-OE1 2.71Å; K251-E333 PolarHBondContact NZ-OE1 3.17Å; K251-E333 IonicContact NZ-OE2 2.87Å; K251-E333 PolarHBondContact NZ-OE2 3.38Å
252	W	89	Confident	90.1	Very high	106 Å²	106	56.9 Å²	56.9	40%	0.402	31%	0.314	S	S	.	.			trans	-69.4	128.9	175.5	-78.9	46.5	0	0	0	109.8	L246 R250 I257	L246-W252 HydrophobicContact CB-CB 4.23Å; L246-W252 HydrophobicContact CB-CG 4.19Å; L246-W252 HydrophobicContact CD1-CD2 4.49Å; L246-W252 PolarHBondContact O-N 3.24Å; R250-W252 VanDerWaalsContact CB-CD1 3.45Å; R250-W252 PolarHBondContact O-N 2.86Å; W252-I257 HydrophobicContact CB-CD1 4.16Å; W252-I257 HydrophobicContact CB-CG1 3.97Å; W252-I257 HydrophobicContact CE3-CG1 3.99Å
253	V	88.1	Confident	90.1	Very high	95 Å²	95	61.9 Å²	61.9	58%	0.576	33%	0.332	S	S	*	.			trans	-74.3	142.2	173.1	-158.7	0	0	0	0	108.1	K251 E255 G256 I257	K251-V253 PolarHBondContact O-N 2.8Å; V253-E255 WeakPolarHBondContact CG1-OE2 3.39Å; V253-E255 PolarHBondContact O-N 3.01Å; V253-E255 VanDerWaalsContact O-N 3.08Å; V253-G256 PolarHBondContact O-N 2.82Å; V253-I257 PolarHBondContact O-N 3.42Å
254	P	86.6	Confident	90.1	Very high	35 Å²	35	62.3 Å²	62.3	23%	0.227	33%	0.334	C	S	.	.	H	α-helix	trans	-52.2	-33.2	-176.9	-31.7	37.3	0	0	0	115.2	R166 G256 I257 E258	R166-P254 HydrophobicContact CB-CB 4Å; P254-G256 VanDerWaalsContact C-N 3.32Å; P254-G256 PolarHBondContact O-N 3.17Å; P254-I257 PolarHBondContact O-N 3.5Å; P254-E258 WeakPolarHBondContact O-CB 3.37Å; P254-E258 PolarHBondContact O-N 3.32Å
255	E	88.3	Confident	90.2	Very high	92 Å²	92	63.9 Å²	63.9	43%	0.43	34%	0.341	S	S	.	.	H	α-helix	trans	-59.7	-39.8	175.2	-71.6	79.8	175	0	0	112.1	R166 V253 E258 A259	R166-E255 IonicContact CZ-OE1 3.82Å; R166-E255 IonicContact NH1-OE1 2.79Å; R166-E255 PolarHBondContact NH1-OE1 3.35Å; R166-E255 IonicContact NH1-OE2 2.63Å; R166-E255 IonicContact NH2-OE1 2.7Å; V253-E255 WeakPolarHBondContact CG1-OE2 3.39Å; V253-E255 PolarHBondContact O-N 3.01Å; V253-E255 VanDerWaalsContact O-N 3.08Å; E255-E258 PolarHBondContact O-N 3.15Å; E255-A259 PolarHBondContact O-N 2.67Å; E255-A259 VanDerWaalsContact O-N 3.09Å
256	G	88.2	Confident	90.3	Very high	29 Å²	29	68.6 Å²	68.6	30%	0.299	36%	0.364	S	S	.	.	H	α-helix	trans	-69.6	-34.7	177.3	0	0	0	0	0	112.5	V253 P254	V253-G256 PolarHBondContact O-N 2.82Å; P254-G256 VanDerWaalsContact C-N 3.32Å; P254-G256 PolarHBondContact O-N 3.17Å
257	I	89.1	Confident	90.4	Very high	4 Å²	4	70 Å²	70	2%	0.021	37%	0.372	C	S	.	.	H	α-helix	trans	-70.3	-38.9	174.4	-56.6	176.7	0	0	0	110.1	F167 T243 L246 W252 V253 P254 A259 C260 S261	F167-I257 HydrophobicContact CB-CB 4.14Å; F167-I257 HydrophobicContact CB-CG2 3.74Å; F167-I257 HydrophobicContact CD1-CG2 4.17Å; F167-I257 HydrophobicContact CD2-CG2 4.17Å; F167-I257 HydrophobicContact CG-CB 4.5Å; F167-I257 HydrophobicContact CG-CG2 3.77Å; T243-I257 HydrophobicContact CG2-CG2 3.83Å; L246-I257 HydrophobicContact CB-CD1 4.41Å; W252-I257 HydrophobicContact CB-CD1 4.16Å; W252-I257 HydrophobicContact CB-CG1 3.97Å; W252-I257 HydrophobicContact CE3-CG1 3.99Å; V253-I257 PolarHBondContact O-N 3.42Å; P254-I257 PolarHBondContact O-N 3.5Å; I257-A259 VanDerWaalsContact C-N 3.33Å; I257-A259 PolarHBondContact O-N 3.03Å; I257-C260 CarbonylContact O-C 3.55Å; I257-C260 PolarHBondContact O-N 3.18Å; I257-S261 PolarHBondContact O-N 3.17Å
258	E	88.5	Confident	90.7	Very high	78 Å²	78	67.9 Å²	67.9	36%	0.364	36%	0.358	S	S	.	.	H	α-helix	trans	-63.6	-37.3	178.5	-174	158.7	-148.7	0	0	112.5	F167 R170 P254 E255 C260 S261	F167-E258 HydrophobicContact CD2-CB 4.3Å; R170-E258 IonicContact NH1-OE1 3.51Å; R170-E258 PolarHBondContact NH1-OE1 2.67Å; P254-E258 WeakPolarHBondContact O-CB 3.37Å; P254-E258 PolarHBondContact O-N 3.32Å; E255-E258 PolarHBondContact O-N 3.15Å; E258-C260 PolarHBondContact O-N 2.91Å; E258-S261 WeakPolarHBondContact O-CB 3.48Å; E258-S261 PolarHBondContact O-N 3.4Å; E258-S261 PolarHBondContact O-OG 3.49Å
259	A	90.2	Very high	91.3	Very high	85 Å²	85	70.5 Å²	70.5	70%	0.702	37%	0.365	S	S	*	.	H	α-helix	trans	-59.3	-27.3	172.7	0	0	0	0	0	113.2	E255 I257	E255-A259 PolarHBondContact O-N 2.67Å; E255-A259 VanDerWaalsContact O-N 3.09Å; I257-A259 VanDerWaalsContact C-N 3.33Å; I257-A259 PolarHBondContact O-N 3.03Å
260	C	90.1	Very high	91.8	Very high	49 Å²	49	70.6 Å²	70.6	33%	0.331	37%	0.366	S	S	.	.	T	Hydrogen-bonded Turn	trans	-102.4	11.5	177	-60.4	0	0	0	0	113.6	I257 E258 S262 Y263	I257-C260 CarbonylContact O-C 3.55Å; I257-C260 PolarHBondContact O-N 3.18Å; E258-C260 PolarHBondContact O-N 2.91Å; C260-S262 PolarHBondContact O-N 3.49Å; C260-S262 VanDerWaalsContact O-N 3.15Å; C260-Y263 HydrophobicContact CB-CD2 4.27Å; C260-Y263 PolarHBondContact O-N 2.94Å
261	S	91.4	Very high	92.3	Very high	24 Å²	24	67.3 Å²	67.3	17%	0.168	36%	0.36	C	S	.	.	H	α-helix	trans	-58.6	-30.8	-173.1	58.2	0	0	0	0	114	I257 E258 Y263 V264 H265	I257-S261 PolarHBondContact O-N 3.17Å; E258-S261 WeakPolarHBondContact O-CB 3.48Å; E258-S261 PolarHBondContact O-N 3.4Å; E258-S261 PolarHBondContact O-OG 3.49Å; S261-Y263 VanDerWaalsContact C-N 3.26Å; S261-Y263 PolarHBondContact O-N 3.5Å; S261-V264 WeakPolarHBondContact O-CB 3.45Å; S261-V264 PolarHBondContact O-N 2.72Å; S261-V264 VanDerWaalsContact O-N 3.09Å; S261-H265 PolarHBondContact O-CD2 3.25Å; S261-H265 VanDerWaalsContact O-CD2 3.23Å; S261-H265 PolarHBondContact O-N 3Å
262	S	94.2	Very high	92.8	Very high	89 Å²	89	61.2 Å²	61.2	62%	0.622	33%	0.333	S	S	*	.	H	α-helix	trans	-56	-38.1	175.5	-55.2	0	0	0	0	113	C260 H265 F266	C260-S262 PolarHBondContact O-N 3.49Å; C260-S262 VanDerWaalsContact O-N 3.15Å; S262-H265 PolarHBondContact O-N 3.32Å; S262-F266 WeakPolarHBondContact O-CB 3.42Å; S262-F266 PolarHBondContact O-N 2.89Å
263	Y	94.5	Very high	93.2	Very high	173 Å²	173	58.5 Å²	58.5	68%	0.678	33%	0.33	S	S	*	.	H	α-helix	trans	-68.6	-40.2	176.9	-66.7	-78.3	0	0	0	111.8	C260 S261 H265 F266 V267	C260-Y263 HydrophobicContact CB-CD2 4.27Å; C260-Y263 PolarHBondContact O-N 2.94Å; S261-Y263 VanDerWaalsContact C-N 3.26Å; S261-Y263 PolarHBondContact O-N 3.5Å; Y263-H265 VanDerWaalsContact C-N 3.31Å; Y263-H265 PolarHBondContact O-N 3.22Å; Y263-F266 PolarHBondContact O-N 3.15Å; Y263-V267 WeakPolarHBondContact O-CG2 3.38Å; Y263-V267 PolarHBondContact O-N 2.77Å
264	V	94.3	Very high	93.6	Very high	9 Å²	9	58.3 Å²	58.3	6%	0.055	33%	0.325	C	S	.	.	H	α-helix	trans	-59.3	-45.6	176.2	-178.5	0	0	0	0	110.4	F167 W236 M239 S261 A268	F167-V264 HydrophobicContact CE1-CG1 4.34Å; W236-V264 HydrophobicContact CH2-CG1 4.3Å; W236-V264 HydrophobicContact CZ3-CG1 3.78Å; M239-V264 HydrophobicContact CB-CG1 3.81Å; M239-V264 HydrophobicContact CE-CB 4.07Å; M239-V264 HydrophobicContact CE-CG1 3.76Å; M239-V264 HydrophobicContact CE-CG2 3.9Å; M239-V264 HydrophobicContact CG-CG1 3.86Å; S261-V264 WeakPolarHBondContact O-CB 3.45Å; S261-V264 PolarHBondContact O-N 2.72Å; S261-V264 VanDerWaalsContact O-N 3.09Å; V264-A268 PolarHBondContact O-N 3.2Å; V264-A268 VanDerWaalsContact O-N 3.16Å
265	H	95.3	Very high	94.1	Very high	38 Å²	38	57.9 Å²	57.9	18%	0.176	32%	0.324	C	S	.	.	H	α-helix	trans	-64.8	-45	176.2	-82.1	-72.2	0	0	0	113	Y174 W236 S261 S262 Y263 V267 A268 W269	Y174-H265 AromaticContact CD2-CE1 3.92Å; Y174-H265 AromaticContact CE1-CE1 3.87Å; Y174-H265 AromaticContact CE2-CE1 3.34Å; Y174-H265 WeakPolarHBondContact CE2-CE1 3.48Å; Y174-H265 AromaticContact CE2-NE2 3.74Å; Y174-H265 AromaticContact CZ-CE1 3.32Å; Y174-H265 AromaticContact CZ-NE2 3.88Å; W236-H265 AromaticContact CH2-CE1 3.42Å; W236-H265 VanDerWaalsContact CH2-CE1 3.42Å; W236-H265 WeakPolarHBondContact CH2-CE1 3.42Å; W236-H265 AromaticContact CH2-CG 3.97Å; W236-H265 AromaticContact CH2-ND1 3.35Å; W236-H265 VanDerWaalsContact CH2-ND1 3.35Å; W236-H265 WeakPolarHBondContact CH2-ND1 3.34Å; W236-H265 AromaticContact CZ2-CE1 3.81Å; W236-H265 AromaticContact CZ2-ND1 3.51Å; S261-H265 PolarHBondContact O-CD2 3.25Å; S261-H265 VanDerWaalsContact O-CD2 3.23Å; S261-H265 PolarHBondContact O-N 3Å; S262-H265 PolarHBondContact O-N 3.32Å; Y263-H265 VanDerWaalsContact C-N 3.31Å; Y263-H265 PolarHBondContact O-N 3.22Å; H265-V267 PolarHBondContact O-N 2.79Å; H265-A268 PolarHBondContact O-N 2.84Å; H265-W269 AromaticContact ND1-CD1 3.83Å; H265-W269 AromaticContact ND1-NE1 3.61Å; H265-W269 WeakPolarHBondContact O-CB 3.48Å; H265-W269 PolarHBondContact O-N 3.14Å
266	F	96.6	Very high	94.6	Very high	154 Å²	154	53.9 Å²	53.9	68%	0.675	31%	0.306	S	S	*	.	I	π-helix	trans	-61.3	-43.5	179.6	178.6	-98.4	0	0	0	111.8	S262 Y263 G270	S262-F266 WeakPolarHBondContact O-CB 3.42Å; S262-F266 PolarHBondContact O-N 2.89Å; Y263-F266 PolarHBondContact O-N 3.15Å; F266-G270 WeakPolarHBondContact O-CA 3.43Å; F266-G270 PolarHBondContact O-N 3.08Å
267	V	96.1	Very high	95	Very high	48 Å²	48	56.7 Å²	56.7	29%	0.291	31%	0.314	S	S	.	.	I	π-helix	trans	-63.7	-50.9	177.3	172.3	0	0	0	0	110.7	M239 Y263 H265 L271	M239-V267 HydrophobicContact SD-CB 4.11Å; M239-V267 HydrophobicContact SD-CG1 3.8Å; Y263-V267 WeakPolarHBondContact O-CG2 3.38Å; Y263-V267 PolarHBondContact O-N 2.77Å; H265-V267 PolarHBondContact O-N 2.79Å; V267-L271 HydrophobicContact CG1-CD1 3.87Å; V267-L271 VanDerWaalsContact O-CB 3.25Å; V267-L271 WeakPolarHBondContact O-CB 3.44Å; V267-L271 VanDerWaalsContact O-CG 3.31Å; V267-L271 WeakPolarHBondContact O-CG 3.43Å; V267-L271 PolarHBondContact O-N 2.87Å
268	A	96.6	Very high	95.3	Very high	0 Å²	0	59.2 Å²	59.2	0%	0	33%	0.326	C	S	.	.	I	π-helix	trans	-67.4	-49	-174.7	0	0	0	0	0	112.9	L235 W236 M239 V264 H265 S272	L235-A268 HydrophobicContact CB-CB 4.3Å; W236-A268 HydrophobicContact CD2-CB 3.73Å; W236-A268 HydrophobicContact CE3-CB 4.2Å; W236-A268 HydrophobicContact CG-CB 4.11Å; W236-A268 HydrophobicContact CH2-CB 4.25Å; W236-A268 HydrophobicContact CZ2-CB 3.8Å; W236-A268 HydrophobicContact CZ3-CB 4.45Å; M239-A268 HydrophobicContact CG-CB 4.25Å; V264-A268 PolarHBondContact O-N 3.2Å; V264-A268 VanDerWaalsContact O-N 3.16Å; H265-A268 PolarHBondContact O-N 2.84Å; A268-S272 WeakPolarHBondContact O-CB 3.46Å; A268-S272 PolarHBondContact O-OG 2.87Å
269	W	98.1	Very high	95.7	Very high	64 Å²	64	55.5 Å²	55.5	24%	0.242	31%	0.309	C	S	.	.	I	π-helix	trans	-80.3	-42.7	-179.2	-63.6	130.4	0	0	0	112.7	Y174 C178 F228 A232 W236 H265 S272 S273	Y174-W269 HydrophobicContact CD1-CZ2 4.19Å; C178-W269 WeakPolarHBondContact SG-CH2 3.44Å; F228-W269 HydrophobicContact CE1-CE3 4.41Å; F228-W269 HydrophobicContact CE1-CZ3 4.27Å; F228-W269 HydrophobicContact CZ-CE3 4.02Å; F228-W269 HydrophobicContact CZ-CZ3 4.34Å; A232-W269 HydrophobicContact CB-CE3 3.9Å; A232-W269 HydrophobicContact CB-CZ3 3.55Å; W236-W269 AromaticContact CE2-CE2 3.87Å; W236-W269 AromaticContact CE2-CZ2 3.91Å; W236-W269 HydrophobicContact CZ2-CD2 4.45Å; W236-W269 AromaticContact CZ2-CE2 3.74Å; W236-W269 HydrophobicContact CZ2-CZ2 4.08Å; W236-W269 AromaticContact CZ2-NE1 3.49Å; W236-W269 AromaticContact NE1-CD2 3.81Å; W236-W269 AromaticContact NE1-CE2 3.4Å; W236-W269 AromaticContact NE1-CH2 3.47Å; W236-W269 AromaticContact NE1-CZ2 3.22Å; W236-W269 AromaticContact NE1-CZ3 3.86Å; H265-W269 AromaticContact ND1-CD1 3.83Å; H265-W269 AromaticContact ND1-NE1 3.61Å; H265-W269 WeakPolarHBondContact O-CB 3.48Å; H265-W269 PolarHBondContact O-N 3.14Å; W269-S272 PolarHBondContact O-N 3.22Å; W269-S273 WeakPolarHBondContact O-CB 3.41Å; W269-S273 PolarHBondContact O-N 2.87Å; W269-S273 PolarHBondContact O-OG 3.32Å; W269-S273 VanDerWaalsContact O-OG 3.1Å
270	G	97.8	Very high	95.9	Very high	27 Å²	27	53.6 Å²	53.6	28%	0.278	29%	0.287	S	S	.	.	I	π-helix	trans	-64.4	-47	-176.5	0	0	0	0	0	112.5	F266 S272 S273 L274	F266-G270 WeakPolarHBondContact O-CA 3.43Å; F266-G270 PolarHBondContact O-N 3.08Å; G270-S272 VanDerWaalsContact C-N 3.34Å; G270-S272 PolarHBondContact O-N 2.98Å; G270-S273 PolarHBondContact O-N 3.29Å; G270-L274 WeakPolarHBondContact O-CB 3.47Å; G270-L274 PolarHBondContact O-N 3.25Å
271	L	97.2	Very high	96.1	Very high	87 Å²	87	56.8 Å²	56.8	46%	0.455	30%	0.3	S	S	.	.	H	α-helix	trans	-67.7	-34.9	177.9	-63.8	-179.1	0	0	0	112.2	L235 V267 L274 A275	L235-L271 HydrophobicContact CD1-CB 3.69Å; L235-L271 HydrophobicContact CD2-CD1 4.36Å; V267-L271 HydrophobicContact CG1-CD1 3.87Å; V267-L271 VanDerWaalsContact O-CB 3.25Å; V267-L271 WeakPolarHBondContact O-CB 3.44Å; V267-L271 VanDerWaalsContact O-CG 3.31Å; V267-L271 WeakPolarHBondContact O-CG 3.43Å; V267-L271 PolarHBondContact O-N 2.87Å; L271-L274 PolarHBondContact O-N 3.48Å; L271-A275 WeakPolarHBondContact O-CB 3.29Å; L271-A275 PolarHBondContact O-N 3.48Å
272	S	97.9	Very high	96.2	Very high	0 Å²	0	61.6 Å²	61.6	0%	0	32%	0.318	C	S	.	.	H	α-helix	trans	-63.2	-47.3	173.2	-57.3	0	0	0	0	111.7	A232 L235 A268 W269 G270 A275 T276	A232-S272 WeakPolarHBondContact CA-OG 3.41Å; A232-S272 WeakPolarHBondContact CB-OG 3.22Å; A232-S272 PolarHBondContact N-OG 3.41Å; L235-S272 VanDerWaalsContact CD1-OG 3.31Å; L235-S272 WeakPolarHBondContact CD1-OG 3.2Å; A268-S272 WeakPolarHBondContact O-CB 3.46Å; A268-S272 PolarHBondContact O-OG 2.87Å; W269-S272 PolarHBondContact O-N 3.22Å; G270-S272 VanDerWaalsContact C-N 3.34Å; G270-S272 PolarHBondContact O-N 2.98Å; S272-A275 PolarHBondContact O-N 2.93Å; S272-T276 PolarHBondContact O-N 3.37Å; S272-T276 PolarHBondContact O-OG1 3.5Å; S272-T276 VanDerWaalsContact O-OG1 3.12Å
273	S	97.9	Very high	96	Very high	48 Å²	48	61.3 Å²	61.3	34%	0.336	31%	0.309	S	S	.	.	H	α-helix	trans	-61.4	-45.9	177.4	-67	0	0	0	0	110.9	F228 W269 G270 A275 T276 I277	F228-S273 WeakPolarHBondContact CE2-OG 3.4Å; W269-S273 WeakPolarHBondContact O-CB 3.41Å; W269-S273 PolarHBondContact O-N 2.87Å; W269-S273 PolarHBondContact O-OG 3.32Å; W269-S273 VanDerWaalsContact O-OG 3.1Å; G270-S273 PolarHBondContact O-N 3.29Å; S273-A275 PolarHBondContact O-N 3.13Å; S273-T276 PolarHBondContact O-N 3.43Å; S273-I277 WeakPolarHBondContact O-CB 3.32Å; S273-I277 WeakPolarHBondContact O-CG1 3.34Å; S273-I277 PolarHBondContact O-N 2.92Å
274	L	97.7	Very high	96	Very high	92 Å²	92	56.9 Å²	56.9	48%	0.482	29%	0.293	S	S	.	.	H	α-helix	trans	-59.6	-46.7	178.5	-179.3	60.8	0	0	0	111.4	G270 L271 T276 I277 I278	G270-L274 WeakPolarHBondContact O-CB 3.47Å; G270-L274 PolarHBondContact O-N 3.25Å; L271-L274 PolarHBondContact O-N 3.48Å; L274-T276 VanDerWaalsContact C-N 3.34Å; L274-T276 PolarHBondContact O-N 3.34Å; L274-I277 PolarHBondContact O-N 3.05Å; L274-I278 HydrophobicContact CD1-CD1 3.98Å; L274-I278 HydrophobicContact CD1-CG1 4.24Å; L274-I278 HydrophobicContact CG-CD1 3.88Å; L274-I278 WeakPolarHBondContact O-CB 3.37Å; L274-I278 VanDerWaalsContact O-CG1 3.23Å; L274-I278 WeakPolarHBondContact O-CG1 3.23Å; L274-I278 PolarHBondContact O-N 3.31Å
275	A	96.9	Very high	96	Very high	25 Å²	25	56.7 Å²	56.7	21%	0.207	29%	0.292	C	S	.	.	H	α-helix	trans	-59.4	-43.5	176.8	0	0	0	0	0	112	L271 S272 S273 I278 V279	L271-A275 WeakPolarHBondContact O-CB 3.29Å; L271-A275 PolarHBondContact O-N 3.48Å; S272-A275 PolarHBondContact O-N 2.93Å; S273-A275 PolarHBondContact O-N 3.13Å; A275-I278 PolarHBondContact O-N 3.46Å; A275-V279 WeakPolarHBondContact O-CG2 3.14Å; A275-V279 PolarHBondContact O-N 3.43Å; A275-V279 VanDerWaalsContact O-N 3.14Å
276	T	97.2	Very high	95.9	Very high	8 Å²	8	55.1 Å²	55.1	5%	0.049	29%	0.285	C	S	.	.	H	α-helix	trans	-64.8	-44.6	176.7	-61.4	0	0	0	0	112.3	F223 L224 F228 S272 S273 L274 I278 V279 L280	F223-T276 HydrophobicContact CE1-CG2 3.87Å; F223-T276 HydrophobicContact CZ-CG2 3.87Å; L224-T276 HydrophobicContact CD2-CG2 3.8Å; F228-T276 HydrophobicContact CB-CG2 4.44Å; F228-T276 WeakPolarHBondContact CB-OG1 3.49Å; S272-T276 PolarHBondContact O-N 3.37Å; S272-T276 PolarHBondContact O-OG1 3.5Å; S272-T276 VanDerWaalsContact O-OG1 3.12Å; S273-T276 PolarHBondContact O-N 3.43Å; L274-T276 VanDerWaalsContact C-N 3.34Å; L274-T276 PolarHBondContact O-N 3.34Å; T276-I278 VanDerWaalsContact C-N 3.33Å; T276-I278 PolarHBondContact O-N 3.1Å; T276-V279 PolarHBondContact O-N 3.19Å; T276-L280 HydrophobicContact CG2-CD1 4.23Å; T276-L280 WeakPolarHBondContact O-CG 3.43Å; T276-L280 PolarHBondContact O-N 3.46Å
277	I	97.1	Very high	95.7	Very high	88 Å²	88	47.8 Å²	47.8	45%	0.451	25%	0.253	S	S	.	.	H	α-helix	trans	-60.9	-44.3	178	-69.7	167.4	0	0	0	110.4	S273 L274 V279 L280 I281	S273-I277 WeakPolarHBondContact O-CB 3.32Å; S273-I277 WeakPolarHBondContact O-CG1 3.34Å; S273-I277 PolarHBondContact O-N 2.92Å; L274-I277 PolarHBondContact O-N 3.05Å; I277-V279 PolarHBondContact O-N 2.89Å; I277-L280 PolarHBondContact O-N 3.13Å; I277-I281 HydrophobicContact CG2-CD1 3.66Å; I277-I281 HydrophobicContact CG2-CG1 4.31Å; I277-I281 VanDerWaalsContact O-CG1 3.31Å; I277-I281 WeakPolarHBondContact O-CG1 3.3Å; I277-I281 PolarHBondContact O-N 3.46Å
278	I	96.7	Very high	95.6	Very high	57 Å²	57	46.2 Å²	46.2	29%	0.292	24%	0.244	S	C	.	.	H	α-helix	trans	-59.7	-46.6	177.9	-70.7	168.8	0	0	0	110.7	L274 A275 T276 L280 I281 F282 F307	L274-I278 HydrophobicContact CD1-CD1 3.98Å; L274-I278 HydrophobicContact CD1-CG1 4.24Å; L274-I278 HydrophobicContact CG-CD1 3.88Å; L274-I278 WeakPolarHBondContact O-CB 3.37Å; L274-I278 VanDerWaalsContact O-CG1 3.23Å; L274-I278 WeakPolarHBondContact O-CG1 3.23Å; L274-I278 PolarHBondContact O-N 3.31Å; A275-I278 PolarHBondContact O-N 3.46Å; T276-I278 VanDerWaalsContact C-N 3.33Å; T276-I278 PolarHBondContact O-N 3.1Å; I278-L280 VanDerWaalsContact C-N 3.31Å; I278-L280 PolarHBondContact O-N 3.33Å; I278-I281 PolarHBondContact O-N 3.27Å; I278-F282 HydrophobicContact CG2-CD2 3.67Å; I278-F282 HydrophobicContact CG2-CE2 3.75Å; I278-F282 WeakPolarHBondContact O-CD2 3.37Å; I278-F282 PolarHBondContact O-N 3.43Å; I278-F307 HydrophobicContact CG2-CE1 3.58Å; I278-F307 HydrophobicContact CG2-CZ 4Å
279	V	95.9	Very high	95.4	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	25%	0.247	C	C	.	.	H	α-helix	trans	-59.3	-42	177.6	166	0	0	0	0	112.1	F223 Y227 A275 T276 I277 F282 N283 K284 V285 V296 F307	F223-V279 HydrophobicContact CE2-CG1 3.7Å; F223-V279 HydrophobicContact CZ-CB 4.16Å; F223-V279 HydrophobicContact CZ-CG1 3.61Å; Y227-V279 HydrophobicContact CE1-CG2 3.99Å; A275-V279 WeakPolarHBondContact O-CG2 3.14Å; A275-V279 PolarHBondContact O-N 3.43Å; A275-V279 VanDerWaalsContact O-N 3.14Å; T276-V279 PolarHBondContact O-N 3.19Å; I277-V279 PolarHBondContact O-N 2.89Å; V279-F282 PolarHBondContact O-N 2.98Å; V279-N283 PolarHBondContact O-N 3.45Å; V279-K284 HydrophobicContact CG1-CB 4.38Å; V279-K284 PolarHBondContact O-N 2.82Å; V279-K284 VanDerWaalsContact O-N 3.11Å; V279-V285 HydrophobicContact CG1-CG2 3.91Å; V279-V296 HydrophobicContact CB-CG2 4.33Å; V279-V296 HydrophobicContact CG1-CG2 3.41Å; V279-V296 VanDerWaalsContact CG1-CG2 3.41Å; V279-V296 HydrophobicContact CG2-CG1 4.5Å; V279-V296 HydrophobicContact CG2-CG2 3.99Å; V279-F307 HydrophobicContact CG2-CB 4.14Å; V279-F307 HydrophobicContact CG2-CD1 3.67Å; V279-F307 HydrophobicContact CG2-CD2 4.2Å; V279-F307 HydrophobicContact CG2-CE1 4.1Å; V279-F307 HydrophobicContact CG2-CG 3.74Å
280	L	94.8	Very high	95.2	Very high	45 Å²	45	44 Å²	44	24%	0.236	24%	0.236	C	C	.	.	H	α-helix	trans	-64.6	-45.9	177.2	-71	171.8	0	0	0	111.3	F214 L220 F223 T276 I277 I278 F282 N283 V285	F214-L280 HydrophobicContact CD1-CD2 4.33Å; F214-L280 HydrophobicContact CE1-CD2 3.54Å; F214-L280 HydrophobicContact CZ-CD2 4.22Å; L220-L280 HydrophobicContact CD1-CD2 3.91Å; F223-L280 HydrophobicContact CD1-CD2 4.2Å; F223-L280 HydrophobicContact CE1-CD1 4.39Å; F223-L280 HydrophobicContact CE1-CD2 3.59Å; F223-L280 HydrophobicContact CE1-CG 3.87Å; F223-L280 HydrophobicContact CZ-CD2 4.4Å; F223-L280 HydrophobicContact CZ-CG 4.39Å; T276-L280 HydrophobicContact CG2-CD1 4.23Å; T276-L280 WeakPolarHBondContact O-CG 3.43Å; T276-L280 PolarHBondContact O-N 3.46Å; I277-L280 PolarHBondContact O-N 3.13Å; I278-L280 VanDerWaalsContact C-N 3.31Å; I278-L280 PolarHBondContact O-N 3.33Å; L280-F282 VanDerWaalsContact C-N 3.26Å; L280-F282 PolarHBondContact O-N 3.37Å; L280-N283 PolarHBondContact O-N 2.92Å; L280-N283 PolarHBondContact O-OD1 3.42Å; L280-N283 VanDerWaalsContact O-OD1 3.04Å; L280-V285 HydrophobicContact CD2-CG2 4.18Å
281	I	94.8	Very high	95.1	Very high	117 Å²	117	43.5 Å²	43.5	60%	0.6	23%	0.228	S	C	*	.	H	α-helix	trans	-59	-39.5	178.3	-70.6	167.7	0	0	0	111.5	I277 I278 N283	I277-I281 HydrophobicContact CG2-CD1 3.66Å; I277-I281 HydrophobicContact CG2-CG1 4.31Å; I277-I281 VanDerWaalsContact O-CG1 3.31Å; I277-I281 WeakPolarHBondContact O-CG1 3.3Å; I277-I281 PolarHBondContact O-N 3.46Å; I278-I281 PolarHBondContact O-N 3.27Å; I281-N283 VanDerWaalsContact C-N 3.29Å; I281-N283 PolarHBondContact O-N 2.85Å
282	F	92.1	Very high	94.9	Very high	125 Å²	125	39.3 Å²	39.3	55%	0.548	21%	0.206	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86	5.5	179.8	-71.5	-67.1	0	0	0	114.2	I278 V279 L280 K284 F307	I278-F282 HydrophobicContact CG2-CD2 3.67Å; I278-F282 HydrophobicContact CG2-CE2 3.75Å; I278-F282 WeakPolarHBondContact O-CD2 3.37Å; I278-F282 PolarHBondContact O-N 3.43Å; V279-F282 PolarHBondContact O-N 2.98Å; L280-F282 VanDerWaalsContact C-N 3.26Å; L280-F282 PolarHBondContact O-N 3.37Å; F282-K284 HydrophobicContact CB-CG 3.81Å; F282-K284 WeakPolarHBondContact O-CD 3.29Å; F282-K284 WeakPolarHBondContact O-CE 3.17Å; F282-K284 WeakPolarHBondContact O-CG 3.36Å; F282-K284 PolarHBondContact O-N 2.88Å; F282-F307 HydrophobicContact CD2-CZ 4.45Å
283	N	91.4	Very high	94.8	Very high	82 Å²	82	39.8 Å²	39.8	44%	0.439	21%	0.209	S	C	.	.	T	Hydrogen-bonded Turn	trans	48.8	42.7	-178.8	-61.6	-31.2	0	0	0	112.6	G212 F214 V279 L280 I281 V285	G212-N283 WeakPolarHBondContact CA-O 3.35Å; F214-N283 WeakPolarHBondContact CE2-OD1 3.27Å; F214-N283 WeakPolarHBondContact CZ-OD1 3.24Å; V279-N283 PolarHBondContact O-N 3.45Å; L280-N283 PolarHBondContact O-N 2.92Å; L280-N283 PolarHBondContact O-OD1 3.42Å; L280-N283 VanDerWaalsContact O-OD1 3.04Å; I281-N283 VanDerWaalsContact C-N 3.29Å; I281-N283 PolarHBondContact O-N 2.85Å; N283-V285 VanDerWaalsContact C-N 3.34Å
284	K	92.9	Very high	94.7	Very high	80 Å²	80	37.6 Å²	37.6	35%	0.348	19%	0.193	S	C	.	.			trans	-96.2	23.4	-177.7	-59.4	-54.7	-180	-170.4	0	113.7	V279 F282 V296 A303 F307	V279-K284 HydrophobicContact CG1-CB 4.38Å; V279-K284 PolarHBondContact O-N 2.82Å; V279-K284 VanDerWaalsContact O-N 3.11Å; F282-K284 HydrophobicContact CB-CG 3.81Å; F282-K284 WeakPolarHBondContact O-CD 3.29Å; F282-K284 WeakPolarHBondContact O-CE 3.17Å; F282-K284 WeakPolarHBondContact O-CG 3.36Å; F282-K284 PolarHBondContact O-N 2.88Å; K284-V296 HydrophobicContact CB-CG1 4.48Å; K284-A303 HydrophobicContact CB-CB 4.17Å; K284-A303 HydrophobicContact CG-CB 4.43Å; K284-F307 HydrophobicContact CB-CE2 4.47Å; K284-F307 HydrophobicContact CG-CE2 4.13Å
285	V	94.3	Very high	94.6	Very high	6 Å²	6	34.1 Å²	34.1	4%	0.036	18%	0.177	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-87.3	128	174.2	-177.5	0	0	0	0	108.9	G212 F223 V279 L280 N283 C294	G212-V285 PolarHBondContact N-O 3.5Å; F223-V285 HydrophobicContact CB-CG1 3.8Å; F223-V285 HydrophobicContact CD1-CG1 4.44Å; F223-V285 HydrophobicContact CD1-CG2 3.9Å; F223-V285 HydrophobicContact CD2-CG1 4.16Å; F223-V285 HydrophobicContact CD2-CG2 3.93Å; F223-V285 HydrophobicContact CE1-CG2 3.93Å; F223-V285 HydrophobicContact CE2-CG2 3.97Å; F223-V285 HydrophobicContact CG-CG1 3.86Å; F223-V285 HydrophobicContact CG-CG2 3.89Å; F223-V285 HydrophobicContact CZ-CG2 3.96Å; V279-V285 HydrophobicContact CG1-CG2 3.91Å; L280-V285 HydrophobicContact CD2-CG2 4.18Å; N283-V285 VanDerWaalsContact C-N 3.34Å; V285-C294 HydrophobicContact CG1-CB 4.16Å
286	D	93.3	Very high	94.4	Very high	5 Å²	5	33.1 Å²	33.1	3%	0.027	17%	0.168	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-144.8	141.9	-178.3	62.4	-89.6	0	0	0	112.5	S295 G297 N298 L299	D286-S295 PolarHBondContact N-O 2.89Å; D286-S295 PolarHBondContact O-N 2.83Å; D286-S295 VanDerWaalsContact O-N 3.09Å; D286-G297 PolarHBondContact OD1-N 3.48Å; D286-N298 PolarHBondContact O-ND2 3.49Å; D286-N298 WeakPolarHBondContact OD2-CA 3.48Å; D286-N298 WeakPolarHBondContact OD2-CB 3.31Å; D286-N298 PolarHBondContact OD2-N 3.14Å; D286-L299 PolarHBondContact OD2-N 3.24Å
287	A	94.1	Very high	94.2	Very high	0 Å²	0	32.7 Å²	32.7	0%	0	17%	0.166	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-77.7	145.2	-179.3	0	0	0	0	0	112.3	S198 L209 S210 C294	S198-A287 WeakPolarHBondContact O-CB 3.32Å; L209-A287 HydrophobicContact CD1-CB 3.62Å; L209-A287 HydrophobicContact CD2-CB 4.37Å; L209-A287 VanDerWaalsContact CD2-O 3.27Å; L209-A287 WeakPolarHBondContact CD2-O 3.23Å; L209-A287 HydrophobicContact CG-CB 3.6Å; S210-A287 PolarHBondContact O-N 2.94Å; A287-C294 VanDerWaalsContact CB-SG 3.58Å
288	S	93.9	Very high	94	Very high	14 Å²	14	29.7 Å²	29.7	10%	0.098	15%	0.15	C	C	.	.			trans	-90.2	127	173.1	-177.1	0	0	0	0	111.4	L290 T291 A292 L293	S288-L290 VanDerWaalsContact C-N 3.25Å; S288-L290 PolarHBondContact O-N 2.89Å; S288-L290 PolarHBondContact OG-N 3.01Å; S288-T291 WeakPolarHBondContact CB-OG1 3.48Å; S288-T291 PolarHBondContact OG-N 3.1Å; S288-T291 PolarHBondContact OG-OG1 2.93Å; S288-A292 VanDerWaalsContact O-CA 3.22Å; S288-A292 WeakPolarHBondContact O-CA 3.34Å; S288-A292 PolarHBondContact O-N 3.38Å; S288-L293 WeakPolarHBondContact CB-O 3.34Å; S288-L293 PolarHBondContact N-O 2.92Å
289	E	92.3	Very high	93.7	Very high	14 Å²	14	28.3 Å²	28.3	7%	0.065	14%	0.144	C	C	.	.	T	Hydrogen-bonded Turn	trans	-60.1	-38.2	172.1	-168.6	-165.6	150.1	0	0	111.6	V126 M127 F128 K133 R137 L209	V126-E289 PolarHBondContact N-OE1 2.84Å; V126-E289 VanDerWaalsContact N-OE1 3.09Å; M127-E289 WeakPolarHBondContact CB-OE2 3.31Å; M127-E289 PolarHBondContact N-OE2 3.27Å; F128-E289 PolarHBondContact N-OE1 3.49Å; K133-E289 WeakPolarHBondContact CE-OE1 3.38Å; K133-E289 IonicContact NZ-OE1 3.9Å; K133-E289 PolarHBondContact NZ-OE1 3.29Å; R137-E289 PolarHBondContact NH2-O 3Å; L209-E289 HydrophobicContact CD2-CB 4.27Å
290	L	93.8	Very high	93.4	Very high	3 Å²	3	31 Å²	31	2%	0.016	16%	0.158	C	C	.	.	T	Hydrogen-bonded Turn	trans	-74.7	-54.7	-173.1	-172.4	64.4	0	0	0	111.7	F128 N132 K133 V136 R137 S288 Y407	F128-L290 HydrophobicContact CB-CD1 4.11Å; F128-L290 HydrophobicContact CD1-CD1 4.04Å; F128-L290 HydrophobicContact CD2-CB 3.93Å; F128-L290 HydrophobicContact CD2-CD1 4.18Å; F128-L290 HydrophobicContact CE1-CD2 4.35Å; F128-L290 HydrophobicContact CE2-CB 4.02Å; F128-L290 HydrophobicContact CE2-CD2 4.43Å; F128-L290 HydrophobicContact CG-CB 4.46Å; F128-L290 HydrophobicContact CG-CD1 3.84Å; F128-L290 HydrophobicContact CZ-CD2 4.23Å; N132-L290 HydrophobicContact CB-CD1 4.41Å; K133-L290 HydrophobicContact CG-CD1 4.47Å; V136-L290 HydrophobicContact CB-CD1 4.04Å; V136-L290 HydrophobicContact CB-CD2 4.39Å; V136-L290 HydrophobicContact CB-CG 4Å; V136-L290 HydrophobicContact CG1-CD2 4.08Å; V136-L290 HydrophobicContact CG1-CG 3.91Å; V136-L290 HydrophobicContact CG2-CD1 3.85Å; V136-L290 HydrophobicContact CG2-CD2 4.08Å; V136-L290 HydrophobicContact CG2-CG 4.06Å; R137-L290 PolarHBondContact NE-O 3.44Å; S288-L290 VanDerWaalsContact C-N 3.25Å; S288-L290 PolarHBondContact O-N 2.89Å; S288-L290 PolarHBondContact OG-N 3.01Å; L290-Y407 HydrophobicContact CD2-CD1 4.39Å; L290-Y407 HydrophobicContact CD2-CG 4.26Å
291	T	94.7	Very high	93.4	Very high	17 Å²	17	29.7 Å²	29.7	10%	0.104	15%	0.153	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91	-17.7	-175	59	0	0	0	0	113.6	V136 S288 L293 V411	V136-T291 HydrophobicContact CG1-CG2 4.15Å; S288-T291 WeakPolarHBondContact CB-OG1 3.48Å; S288-T291 PolarHBondContact OG-N 3.1Å; S288-T291 PolarHBondContact OG-OG1 2.93Å; T291-L293 PolarHBondContact O-N 3.44Å; T291-V411 HydrophobicContact CG2-CG2 4.04Å
292	A	94.4	Very high	93.3	Very high	0 Å²	0	29.4 Å²	29.4	0%	0	15%	0.151	C	C	.	.			trans	56	38	-170.2	0	0	0	0	0	112.9	A194 R197 S288	A194-A292 HydrophobicContact CB-CB 3.65Å; R197-A292 WeakPolarHBondContact CB-O 3.39Å; R197-A292 PolarHBondContact NE-O 3.31Å; S288-A292 VanDerWaalsContact O-CA 3.22Å; S288-A292 WeakPolarHBondContact O-CA 3.34Å; S288-A292 PolarHBondContact O-N 3.38Å
293	L	94.8	Very high	93.5	Very high	10 Å²	10	23.6 Å²	23.6	5%	0.052	13%	0.126	C	C	.	.			trans	-121.9	149.1	172.2	-60.4	177.4	0	0	0	109.6	P185 Y186 S288 T291	P185-L293 HydrophobicContact CB-CD1 4.06Å; P185-L293 HydrophobicContact CB-CD2 4.04Å; P185-L293 VanDerWaalsContact O-CD2 3.3Å; P185-L293 WeakPolarHBondContact O-CD2 3.46Å; Y186-L293 HydrophobicContact CD1-CD1 3.43Å; Y186-L293 VanDerWaalsContact CD1-CD1 3.43Å; Y186-L293 HydrophobicContact CD2-CD1 4.35Å; Y186-L293 HydrophobicContact CE1-CD1 3.53Å; Y186-L293 HydrophobicContact CE2-CD1 4.46Å; Y186-L293 HydrophobicContact CG-CD1 3.87Å; S288-L293 WeakPolarHBondContact CB-O 3.34Å; S288-L293 PolarHBondContact N-O 2.92Å; T291-L293 PolarHBondContact O-N 3.44Å
294	C	95.3	Very high	93.7	Very high	1 Å²	1	19.7 Å²	19.7	1%	0.007	11%	0.105	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-93.8	136.4	175	-61.3	0	0	0	0	111.3	C219 S222 F223 V285 A287	C219-C294 WeakPolarHBondContact CA-SG 3.46Å; C219-C294 HydrophobicContact CB-CB 4Å; C219-C294 WeakPolarHBondContact CB-SG 3.31Å; C219-C294 VanDerWaalsContact O-CB 3.26Å; C219-C294 WeakPolarHBondContact O-CB 3.04Å; C219-C294 WeakPolarHBondContact SG-CB 3.16Å; C219-C294 CovalentContact SG-SG 2.01Å; C219-C294 PolarHBondContact SG-SG 3.28Å; S222-C294 CarbonylContact C-O 3.31Å; F223-C294 VanDerWaalsContact CA-O 3.23Å; F223-C294 WeakPolarHBondContact CA-O 3.01Å; F223-C294 HydrophobicContact CB-CB 4.31Å; F223-C294 PolarHBondContact N-O 2.83Å; V285-C294 HydrophobicContact CG1-CB 4.16Å; A287-C294 VanDerWaalsContact CB-SG 3.58Å
295	S	95.2	Very high	93.9	Very high	20 Å²	20	18.3 Å²	18.3	14%	0.14	10%	0.101	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-155.9	-160.6	174.1	-163.5	0	0	0	0	108.2	N226 D286 N298	N226-S295 PolarHBondContact OD1-OG 2.92Å; D286-S295 PolarHBondContact N-O 2.89Å; D286-S295 PolarHBondContact O-N 2.83Å; D286-S295 VanDerWaalsContact O-N 3.09Å; S295-N298 PolarHBondContact N-ND2 3.42Å
296	V	94.6	Very high	94.1	Very high	3 Å²	3	25.6 Å²	25.6	2%	0.018	13%	0.128	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-103.8	132.3	178.4	-173	0	0	0	0	110.1	F223 Y227 V279 K284 A303 F307 V308	F223-V296 HydrophobicContact CD2-CG2 4.13Å; F223-V296 HydrophobicContact CE2-CG2 3.57Å; Y227-V296 HydrophobicContact CD1-CG2 4.49Å; Y227-V296 HydrophobicContact CD2-CB 4.31Å; Y227-V296 HydrophobicContact CD2-CG2 3.79Å; Y227-V296 HydrophobicContact CE2-CB 4.22Å; Y227-V296 HydrophobicContact CE2-CG2 3.84Å; Y227-V296 HydrophobicContact CG-CG2 4.13Å; V279-V296 HydrophobicContact CB-CG2 4.33Å; V279-V296 HydrophobicContact CG1-CG2 3.41Å; V279-V296 VanDerWaalsContact CG1-CG2 3.41Å; V279-V296 HydrophobicContact CG2-CG1 4.5Å; V279-V296 HydrophobicContact CG2-CG2 3.99Å; K284-V296 HydrophobicContact CB-CG1 4.48Å; V296-A303 HydrophobicContact CG1-CB 3.86Å; V296-F307 HydrophobicContact CG1-CB 3.8Å; V296-F307 HydrophobicContact CG1-CD2 4.06Å; V296-F307 HydrophobicContact CG1-CG 4.28Å; V296-V308 HydrophobicContact CB-CG2 4.27Å
297	G	92.8	Very high	94.2	Very high	0 Å²	0	27.4 Å²	27.4	0%	0	14%	0.136	C	C	.	.	S	Bend	trans	74	36.8	170.4	0	0	0	0	0	113.6	D286 N300 K375	D286-G297 PolarHBondContact OD1-N 3.48Å; G297-N300 VanDerWaalsContact CA-O 3.31Å; G297-N300 WeakPolarHBondContact CA-O 2.97Å; G297-K375 WeakPolarHBondContact O-CE 3.37Å; G297-K375 PolarHBondContact O-NZ 3.36Å
298	N	93.1	Very high	94.3	Very high	24 Å²	24	28.6 Å²	28.6	13%	0.128	14%	0.143	C	C	.	.	S	Bend	trans	-76.7	-38.6	165.6	-61	-54.3	0	0	0	112.1	D286 S295 K375	D286-N298 PolarHBondContact O-ND2 3.49Å; D286-N298 WeakPolarHBondContact OD2-CA 3.48Å; D286-N298 WeakPolarHBondContact OD2-CB 3.31Å; D286-N298 PolarHBondContact OD2-N 3.14Å; S295-N298 PolarHBondContact N-ND2 3.42Å; N298-K375 PolarHBondContact OD1-NZ 2.89Å
299	L	89	Confident	94.5	Very high	29 Å²	29	28.5 Å²	28.5	15%	0.152	14%	0.141	C	C	.	.	S	Bend	trans	-113.5	-21.9	178.3	-59.9	-179.8	0	0	0	112.7	F120 M127 L209 I211 D286	F120-L299 HydrophobicContact CD2-CD2 4.02Å; F120-L299 HydrophobicContact CE2-CD2 3.59Å; F120-L299 HydrophobicContact CZ-CD2 4.16Å; M127-L299 HydrophobicContact CE-CD2 3.37Å; L209-L299 HydrophobicContact CD2-CD1 3.97Å; I211-L299 HydrophobicContact CD1-CD1 3.88Å; I211-L299 HydrophobicContact CG1-CD1 3.92Å; D286-L299 PolarHBondContact OD2-N 3.24Å
300	N	90.9	Very high	94.8	Very high	55 Å²	55	29.9 Å²	29.9	29%	0.294	15%	0.151	S	C	.	.			trans	-104.8	110.9	-176.3	-169.3	-52.3	0	0	0	112	G297 I302 A303 L304	G297-N300 VanDerWaalsContact CA-O 3.31Å; G297-N300 WeakPolarHBondContact CA-O 2.97Å; N300-I302 PolarHBondContact O-N 3.04Å; N300-I302 PolarHBondContact OD1-N 2.96Å; N300-A303 HydrophobicContact CB-CB 3.93Å; N300-A303 PolarHBondContact O-N 2.95Å; N300-A303 PolarHBondContact OD1-N 3.32Å; N300-L304 WeakPolarHBondContact O-CB 3.26Å; N300-L304 PolarHBondContact O-N 3.49Å
301	S	93.4	Very high	94.9	Very high	19 Å²	19	32.1 Å²	32.1	13%	0.133	17%	0.165	C	C	.	.	H	α-helix	trans	-67.7	-33.3	-178.8	59	0	0	0	0	113.7	L304 L305 F376 T380	S301-L304 PolarHBondContact O-N 2.88Å; S301-L305 PolarHBondContact O-N 3.35Å; S301-F376 WeakPolarHBondContact O-CD2 3.17Å; S301-F376 WeakPolarHBondContact O-CE2 3.1Å; S301-T380 WeakPolarHBondContact CB-OG1 3.3Å
302	I	93.4	Very high	95	Very high	111 Å²	111	32.9 Å²	32.9	57%	0.569	17%	0.166	S	C	*	.	H	α-helix	trans	-69.5	-43.6	178.9	-59.7	174.9	0	0	0	110.1	N300 L304 L305 W306	N300-I302 PolarHBondContact O-N 3.04Å; N300-I302 PolarHBondContact OD1-N 2.96Å; I302-L304 VanDerWaalsContact C-N 3.35Å; I302-L305 PolarHBondContact O-N 3.46Å; I302-W306 PolarHBondContact O-N 3.39Å; I302-W306 VanDerWaalsContact O-N 3.11Å
303	A	95.5	Very high	95.2	Very high	2 Å²	2	35.2 Å²	35.2	2%	0.017	18%	0.18	C	C	.	.	H	α-helix	trans	-63.9	-41.9	175.5	0	0	0	0	0	111.2	K284 V296 N300 L305 F307	K284-A303 HydrophobicContact CB-CB 4.17Å; K284-A303 HydrophobicContact CG-CB 4.43Å; V296-A303 HydrophobicContact CG1-CB 3.86Å; N300-A303 HydrophobicContact CB-CB 3.93Å; N300-A303 PolarHBondContact O-N 2.95Å; N300-A303 PolarHBondContact OD1-N 3.32Å; A303-L305 VanDerWaalsContact C-N 3.32Å; A303-L305 PolarHBondContact O-N 2.9Å; A303-F307 HydrophobicContact CB-CD2 4.12Å; A303-F307 WeakPolarHBondContact O-CB 3.1Å; A303-F307 PolarHBondContact O-N 3.1Å
304	L	96.6	Very high	95.3	Very high	1 Å²	1	38.9 Å²	38.9	1%	0.005	20%	0.199	C	C	.	.	I	π-helix	trans	-57.2	-44.5	174.3	-179.3	63.2	0	0	0	111.9	N300 S301 I302 V308 I309 K375 F376 L379	N300-L304 WeakPolarHBondContact O-CB 3.26Å; N300-L304 PolarHBondContact O-N 3.49Å; S301-L304 PolarHBondContact O-N 2.88Å; I302-L304 VanDerWaalsContact C-N 3.35Å; L304-V308 HydrophobicContact CD1-CB 4.04Å; L304-V308 HydrophobicContact CD1-CG1 4.31Å; L304-V308 HydrophobicContact CD1-CG2 4.26Å; L304-V308 VanDerWaalsContact O-CB 3.32Å; L304-V308 WeakPolarHBondContact O-CB 3.27Å; L304-V308 PolarHBondContact O-N 3.48Å; L304-I309 HydrophobicContact CD2-CD1 4.46Å; L304-I309 HydrophobicContact CG-CD1 4.05Å; L304-I309 HydrophobicContact CG-CG1 4.36Å; L304-I309 PolarHBondContact O-N 3.22Å; L304-K375 HydrophobicContact CD1-CD 4.37Å; L304-K375 HydrophobicContact CD2-CB 4.15Å; L304-K375 HydrophobicContact CD2-CD 3.77Å; L304-K375 HydrophobicContact CD2-CG 3.73Å; L304-F376 HydrophobicContact CD2-CB 3.98Å; L304-L379 HydrophobicContact CD2-CD1 4.03Å
305	L	97.1	Very high	95.4	Very high	50 Å²	50	39.6 Å²	39.6	26%	0.262	20%	0.204	S	C	.	.	I	π-helix	trans	-62.3	-57.1	179.4	178.6	63.1	0	0	0	111.8	S301 I302 A303 I309 V310 F376	S301-L305 PolarHBondContact O-N 3.35Å; I302-L305 PolarHBondContact O-N 3.46Å; A303-L305 VanDerWaalsContact C-N 3.32Å; A303-L305 PolarHBondContact O-N 2.9Å; L305-I309 HydrophobicContact CD1-CB 4.48Å; L305-I309 HydrophobicContact CD1-CG2 4.42Å; L305-I309 PolarHBondContact O-N 3.48Å; L305-V310 HydrophobicContact CD1-CG2 4.17Å; L305-V310 HydrophobicContact CG-CG2 4.41Å; L305-V310 WeakPolarHBondContact O-CG2 3.29Å; L305-V310 PolarHBondContact O-N 3.38Å; L305-F376 HydrophobicContact CB-CD2 4.11Å; L305-F376 HydrophobicContact CB-CE2 3.85Å; L305-F376 HydrophobicContact CD2-CE2 4.17Å; L305-F376 HydrophobicContact CD2-CZ 4.25Å; L305-F376 HydrophobicContact CG-CE2 4.41Å
306	W	96.8	Very high	95.4	Very high	159 Å²	159	39.6 Å²	39.6	60%	0.602	20%	0.202	S	C	*	.	I	π-helix	trans	-81.1	-32.1	-168.4	-73.7	112.7	0	0	0	114.4	I302 V310 P311	I302-W306 PolarHBondContact O-N 3.39Å; I302-W306 VanDerWaalsContact O-N 3.11Å; W306-V310 HydrophobicContact CE3-CB 4.47Å; W306-V310 HydrophobicContact CE3-CG1 4.44Å; W306-V310 HydrophobicContact CE3-CG2 4.17Å; W306-V310 HydrophobicContact CZ3-CG2 4.37Å; W306-P311 VanDerWaalsContact O-CD 3.24Å; W306-P311 WeakPolarHBondContact O-CD 3.37Å; W306-P311 WeakPolarHBondContact O-CG 3.06Å
307	F	96.8	Very high	95.6	Very high	44 Å²	44	43.4 Å²	43.4	19%	0.193	23%	0.225	C	C	.	.	I	π-helix	trans	-98.2	-18.7	-176.9	-63.9	-63	0	0	0	113.6	Y227 I278 V279 F282 K284 V296 A303	Y227-F307 PolarHBondContact OH-O 2.05Å; I278-F307 HydrophobicContact CG2-CE1 3.58Å; I278-F307 HydrophobicContact CG2-CZ 4Å; V279-F307 HydrophobicContact CG2-CB 4.14Å; V279-F307 HydrophobicContact CG2-CD1 3.67Å; V279-F307 HydrophobicContact CG2-CD2 4.2Å; V279-F307 HydrophobicContact CG2-CE1 4.1Å; V279-F307 HydrophobicContact CG2-CG 3.74Å; F282-F307 HydrophobicContact CD2-CZ 4.45Å; K284-F307 HydrophobicContact CB-CE2 4.47Å; K284-F307 HydrophobicContact CG-CE2 4.13Å; V296-F307 HydrophobicContact CG1-CB 3.8Å; V296-F307 HydrophobicContact CG1-CD2 4.06Å; V296-F307 HydrophobicContact CG1-CG 4.28Å; A303-F307 HydrophobicContact CB-CD2 4.12Å; A303-F307 WeakPolarHBondContact O-CB 3.1Å; A303-F307 PolarHBondContact O-N 3.1Å
308	V	96.8	Very high	95.8	Very high	24 Å²	24	46.9 Å²	46.9	15%	0.145	24%	0.243	C	C	.	.	I	π-helix	trans	-118.3	-60.7	-177.4	-173.7	0	0	0	0	111.5	Y227 V296 L304 R312	Y227-V308 HydrophobicContact CE2-CG2 4.35Å; V296-V308 HydrophobicContact CB-CG2 4.27Å; L304-V308 HydrophobicContact CD1-CB 4.04Å; L304-V308 HydrophobicContact CD1-CG1 4.31Å; L304-V308 HydrophobicContact CD1-CG2 4.26Å; L304-V308 VanDerWaalsContact O-CB 3.32Å; L304-V308 WeakPolarHBondContact O-CB 3.27Å; L304-V308 PolarHBondContact O-N 3.48Å; V308-R312 WeakPolarHBondContact O-CB 3.48Å; V308-R312 PolarHBondContact O-N 3.49Å
309	I	98	Very high	96	Very high	13 Å²	13	45.7 Å²	45.7	7%	0.067	24%	0.237	C	C	.	.	I	π-helix	trans	-66.9	-52	-172.1	-65.8	174.4	0	0	0	111.4	L304 L305 T313 L369 Q372 F376	L304-I309 HydrophobicContact CD2-CD1 4.46Å; L304-I309 HydrophobicContact CG-CD1 4.05Å; L304-I309 HydrophobicContact CG-CG1 4.36Å; L304-I309 PolarHBondContact O-N 3.22Å; L305-I309 HydrophobicContact CD1-CB 4.48Å; L305-I309 HydrophobicContact CD1-CG2 4.42Å; L305-I309 PolarHBondContact O-N 3.48Å; I309-T313 VanDerWaalsContact O-CB 3.29Å; I309-T313 WeakPolarHBondContact O-CB 3.46Å; I309-T313 PolarHBondContact O-N 2.83Å; I309-T313 PolarHBondContact O-OG1 2.86Å; I309-L369 HydrophobicContact CG2-CD1 4.08Å; I309-Q372 HydrophobicContact CD1-CB 4.35Å; I309-Q372 HydrophobicContact CG1-CB 4.04Å; I309-F376 HydrophobicContact CD1-CB 3.76Å; I309-F376 HydrophobicContact CD1-CG 4.31Å
310	V	97.7	Very high	96.4	Very high	43 Å²	43	46.5 Å²	46.5	26%	0.261	24%	0.243	S	C	.	.	H	α-helix	trans	-61.9	-53.6	-176.4	167.6	0	0	0	0	111.8	L305 W306 R312 T313 I314	L305-V310 HydrophobicContact CD1-CG2 4.17Å; L305-V310 HydrophobicContact CG-CG2 4.41Å; L305-V310 WeakPolarHBondContact O-CG2 3.29Å; L305-V310 PolarHBondContact O-N 3.38Å; W306-V310 HydrophobicContact CE3-CB 4.47Å; W306-V310 HydrophobicContact CE3-CG1 4.44Å; W306-V310 HydrophobicContact CE3-CG2 4.17Å; W306-V310 HydrophobicContact CZ3-CG2 4.37Å; V310-R312 VanDerWaalsContact C-N 3.34Å; V310-R312 PolarHBondContact O-N 3.35Å; V310-T313 PolarHBondContact O-N 3.04Å; V310-I314 HydrophobicContact CG1-CD1 3.75Å; V310-I314 VanDerWaalsContact O-CG1 3.31Å; V310-I314 WeakPolarHBondContact O-CG1 3.48Å; V310-I314 PolarHBondContact O-N 3.49Å
311	P	96.6	Very high	96.6	Very high	50 Å²	50	47.8 Å²	47.8	33%	0.325	26%	0.255	S	S	.	.	H	α-helix	trans	-61.7	-41.2	-179.3	-24.7	36.3	0	0	0	112.6	W306 I314 C315	W306-P311 VanDerWaalsContact O-CD 3.24Å; W306-P311 WeakPolarHBondContact O-CD 3.37Å; W306-P311 WeakPolarHBondContact O-CG 3.06Å; P311-I314 PolarHBondContact O-N 2.96Å; P311-C315 PolarHBondContact O-N 2.93Å; P311-C315 PolarHBondContact O-SG 3.08Å; P311-C315 VanDerWaalsContact O-SG 3.36Å
312	R	96.1	Very high	96.8	Very high	33 Å²	33	49.6 Å²	49.6	13%	0.125	26%	0.261	C	S	.	.	H	α-helix	trans	-65.4	-41.9	178.5	-176.2	173.1	-96.6	-111.6	13.4	112.1	V308 V310 C315 I316 N365 E368	V308-R312 WeakPolarHBondContact O-CB 3.48Å; V308-R312 PolarHBondContact O-N 3.49Å; V310-R312 VanDerWaalsContact C-N 3.34Å; V310-R312 PolarHBondContact O-N 3.35Å; R312-C315 PolarHBondContact O-N 3.27Å; R312-I316 HydrophobicContact CG-CD1 3.95Å; R312-I316 WeakPolarHBondContact O-CG1 3.47Å; R312-I316 PolarHBondContact O-N 3.03Å; R312-N365 PolarHBondContact NH1-OD1 2.9Å; R312-E368 IonicContact CZ-OE1 3.67Å; R312-E368 IonicContact CZ-OE2 3.44Å; R312-E368 IonicContact NH1-OE1 3.14Å; R312-E368 IonicContact NH1-OE2 2.9Å; R312-E368 PolarHBondContact NH1-OE2 3.12Å; R312-E368 IonicContact NH2-OE1 3.8Å; R312-E368 PolarHBondContact NH2-OE1 3.35Å; R312-E368 IonicContact NH2-OE2 2.63Å; R312-E368 PolarHBondContact NH2-OE2 2.91Å
313	T	97.8	Very high	96.9	Very high	48 Å²	48	45 Å²	45	29%	0.294	24%	0.237	S	C	.	.	H	α-helix	trans	-60.7	-46.7	175.3	-57.7	0	0	0	0	110.7	I309 V310 C315 I316 V317 L369	I309-T313 VanDerWaalsContact O-CB 3.29Å; I309-T313 WeakPolarHBondContact O-CB 3.46Å; I309-T313 PolarHBondContact O-N 2.83Å; I309-T313 PolarHBondContact O-OG1 2.86Å; V310-T313 PolarHBondContact O-N 3.04Å; T313-C315 PolarHBondContact O-N 2.73Å; T313-I316 PolarHBondContact O-N 2.72Å; T313-V317 HydrophobicContact CG2-CG2 4.23Å; T313-V317 WeakPolarHBondContact O-CB 3.3Å; T313-V317 VanDerWaalsContact O-CG2 3.3Å; T313-V317 WeakPolarHBondContact O-CG2 3.31Å; T313-V317 PolarHBondContact O-N 3.44Å; T313-L369 WeakPolarHBondContact OG1-CD1 3.21Å
314	I	97.5	Very high	96.9	Very high	88 Å²	88	49.2 Å²	49.2	45%	0.451	26%	0.263	S	S	.	.	H	α-helix	trans	-58.3	-49.2	177.2	-69.3	168.1	0	0	0	110.5	V310 P311 I316 V317 I318	V310-I314 HydrophobicContact CG1-CD1 3.75Å; V310-I314 VanDerWaalsContact O-CG1 3.31Å; V310-I314 WeakPolarHBondContact O-CG1 3.48Å; V310-I314 PolarHBondContact O-N 3.49Å; P311-I314 PolarHBondContact O-N 2.96Å; I314-I316 PolarHBondContact O-N 3.43Å; I314-V317 PolarHBondContact O-N 2.78Å; I314-I318 HydrophobicContact CG2-CD1 3.58Å; I314-I318 HydrophobicContact CG2-CG1 4.37Å; I314-I318 WeakPolarHBondContact O-CB 3.34Å; I314-I318 VanDerWaalsContact O-CG1 3.29Å; I314-I318 WeakPolarHBondContact O-CG1 3.44Å; I314-I318 PolarHBondContact O-N 3.44Å
315	C	96.8	Very high	96.8	Very high	15 Å²	15	50.2 Å²	50.2	10%	0.101	27%	0.273	C	S	.	.	H	α-helix	trans	-58.9	-48.4	178.5	-74.2	0	0	0	0	112.2	W237 P311 R312 T313 G319	W237-C315 WeakPolarHBondContact CZ3-O 3.13Å; P311-C315 PolarHBondContact O-N 2.93Å; P311-C315 PolarHBondContact O-SG 3.08Å; P311-C315 VanDerWaalsContact O-SG 3.36Å; R312-C315 PolarHBondContact O-N 3.27Å; T313-C315 PolarHBondContact O-N 2.73Å; C315-G319 PolarHBondContact O-N 3.42Å
316	I	96.5	Very high	96.6	Very high	21 Å²	21	47.9 Å²	47.9	11%	0.108	26%	0.261	C	S	.	.	H	α-helix	trans	-62	-50.7	179.9	-69.3	169.2	0	0	0	110.6	R312 T313 I314 G319 T320 N365 V366 L369	R312-I316 HydrophobicContact CG-CD1 3.95Å; R312-I316 WeakPolarHBondContact O-CG1 3.47Å; R312-I316 PolarHBondContact O-N 3.03Å; T313-I316 PolarHBondContact O-N 2.72Å; I314-I316 PolarHBondContact O-N 3.43Å; I316-G319 PolarHBondContact O-N 3.39Å; I316-T320 VanDerWaalsContact O-CB 3.3Å; I316-T320 WeakPolarHBondContact O-CB 3.39Å; I316-T320 PolarHBondContact O-N 3.37Å; I316-T320 PolarHBondContact O-OG1 3.33Å; I316-N365 HydrophobicContact CD1-CB 4.01Å; I316-V366 HydrophobicContact CG2-CG2 4.28Å; I316-L369 HydrophobicContact CD1-CD2 4.3Å
317	V	97.7	Very high	96.4	Very high	82 Å²	82	42.1 Å²	42.1	50%	0.497	24%	0.24	S	C	.	.	H	α-helix	trans	-61	-52.2	-177.5	171.2	0	0	0	0	111	T313 I314 G319 T320 C321	T313-V317 HydrophobicContact CG2-CG2 4.23Å; T313-V317 WeakPolarHBondContact O-CB 3.3Å; T313-V317 VanDerWaalsContact O-CG2 3.3Å; T313-V317 WeakPolarHBondContact O-CG2 3.31Å; T313-V317 PolarHBondContact O-N 3.44Å; I314-V317 PolarHBondContact O-N 2.78Å; V317-G319 PolarHBondContact O-N 3.4Å; V317-T320 PolarHBondContact O-N 3.49Å; V317-C321 PolarHBondContact O-N 2.9Å; V317-C321 PolarHBondContact O-SG 3.42Å
318	I	98.1	Very high	96.2	Very high	73 Å²	73	42.9 Å²	42.9	37%	0.374	25%	0.254	S	S	.	.	H	α-helix	trans	-64.3	-44	-178.9	-63.1	176.6	0	0	0	110.7	L238 I314 T320 C321 F322	L238-I318 HydrophobicContact CD1-CB 4.07Å; L238-I318 HydrophobicContact CD1-CG2 3.76Å; I314-I318 HydrophobicContact CG2-CD1 3.58Å; I314-I318 HydrophobicContact CG2-CG1 4.37Å; I314-I318 WeakPolarHBondContact O-CB 3.34Å; I314-I318 VanDerWaalsContact O-CG1 3.29Å; I314-I318 WeakPolarHBondContact O-CG1 3.44Å; I314-I318 PolarHBondContact O-N 3.44Å; I318-T320 PolarHBondContact O-N 3.43Å; I318-C321 WeakPolarHBondContact O-CB 3.45Å; I318-C321 PolarHBondContact O-N 3.13Å; I318-F322 HydrophobicContact CG2-CD2 3.89Å; I318-F322 HydrophobicContact CG2-CE2 3.43Å; I318-F322 VanDerWaalsContact CG2-CE2 3.43Å; I318-F322 HydrophobicContact CG2-CZ 4.14Å; I318-F322 WeakPolarHBondContact O-CD2 3.31Å; I318-F322 PolarHBondContact O-N 3.16Å
319	G	96.9	Very high	96	Very high	0 Å²	0	43.2 Å²	43.2	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-62.5	-43.5	179	0	0	0	0	0	112.3	S241 C315 I316 V317 C321 F322 I323	S241-G319 WeakPolarHBondContact CB-O 3.19Å; C315-G319 PolarHBondContact O-N 3.42Å; I316-G319 PolarHBondContact O-N 3.39Å; V317-G319 PolarHBondContact O-N 3.4Å; G319-C321 VanDerWaalsContact C-N 3.35Å; G319-C321 PolarHBondContact O-N 3.41Å; G319-F322 PolarHBondContact O-N 3.35Å; G319-I323 WeakPolarHBondContact O-CG1 3.42Å; G319-I323 PolarHBondContact O-N 3.33Å
320	T	96.3	Very high	95.6	Very high	45 Å²	45	43.4 Å²	43.4	28%	0.276	26%	0.259	S	S	.	.	H	α-helix	trans	-62.5	-40.3	174.9	-62.3	0	0	0	0	111.6	I316 V317 I318 F322 I323 V324	I316-T320 VanDerWaalsContact O-CB 3.3Å; I316-T320 WeakPolarHBondContact O-CB 3.39Å; I316-T320 PolarHBondContact O-N 3.37Å; I316-T320 PolarHBondContact O-OG1 3.33Å; V317-T320 PolarHBondContact O-N 3.49Å; I318-T320 PolarHBondContact O-N 3.43Å; T320-F322 PolarHBondContact O-N 3.06Å; T320-I323 PolarHBondContact O-N 3.49Å; T320-V324 HydrophobicContact CG2-CG2 4.37Å; T320-V324 WeakPolarHBondContact O-CG2 3.29Å; T320-V324 PolarHBondContact O-N 2.94Å
321	C	97.2	Very high	95.2	Very high	82 Å²	82	44 Å²	44	55%	0.554	27%	0.265	S	S	*	.	H	α-helix	trans	-58.9	-44.5	173.7	-69.9	0	0	0	0	112.3	V317 I318 G319 V324 G325	V317-C321 PolarHBondContact O-N 2.9Å; V317-C321 PolarHBondContact O-SG 3.42Å; I318-C321 WeakPolarHBondContact O-CB 3.45Å; I318-C321 PolarHBondContact O-N 3.13Å; G319-C321 VanDerWaalsContact C-N 3.35Å; G319-C321 PolarHBondContact O-N 3.41Å; C321-V324 PolarHBondContact O-N 3.2Å; C321-G325 PolarHBondContact O-N 3.32Å
322	F	97.1	Very high	95	Very high	58 Å²	58	50.8 Å²	50.8	25%	0.254	28%	0.283	S	S	.	.	H	α-helix	trans	-65.1	-41.3	176	-72.5	-46.5	0	0	0	112.6	L238 S241 F242 Y245 I318 G319 T320 G325 G326	L238-F322 HydrophobicContact CD1-CD2 4.24Å; L238-F322 HydrophobicContact CD1-CE2 4.36Å; S241-F322 WeakPolarHBondContact O-CB 3.34Å; F242-F322 HydrophobicContact CB-CD2 4.09Å; F242-F322 HydrophobicContact CB-CE2 4.17Å; F242-F322 HydrophobicContact CD2-CD2 4.44Å; F242-F322 HydrophobicContact CD2-CE1 4.06Å; F242-F322 AromaticContact CD2-CE2 3.94Å; F242-F322 HydrophobicContact CD2-CE2 3.94Å; F242-F322 AromaticContact CD2-CZ 3.75Å; F242-F322 HydrophobicContact CD2-CZ 3.75Å; F242-F322 HydrophobicContact CE2-CZ 4.43Å; Y245-F322 AromaticContact CD1-CD1 3.95Å; Y245-F322 HydrophobicContact CD1-CD1 3.95Å; Y245-F322 HydrophobicContact CD1-CE1 4.28Å; Y245-F322 AromaticContact CG-CD1 3.99Å; Y245-F322 HydrophobicContact CG-CD1 3.99Å; I318-F322 HydrophobicContact CG2-CD2 3.89Å; I318-F322 HydrophobicContact CG2-CE2 3.43Å; I318-F322 VanDerWaalsContact CG2-CE2 3.43Å; I318-F322 HydrophobicContact CG2-CZ 4.14Å; I318-F322 WeakPolarHBondContact O-CD2 3.31Å; I318-F322 PolarHBondContact O-N 3.16Å; G319-F322 PolarHBondContact O-N 3.35Å; T320-F322 PolarHBondContact O-N 3.06Å; F322-G325 PolarHBondContact O-N 3.1Å; F322-G326 PolarHBondContact O-N 3.23Å
323	I	95.3	Very high	94.6	Very high	13 Å²	13	51.4 Å²	51.4	7%	0.067	29%	0.288	C	S	.	.	H	α-helix	trans	-58.6	-52	175.5	-74.8	167.4	0	0	0	110	W237 S241 G319 T320 G325 G326 F327 C358 I362	W237-I323 HydrophobicContact CH2-CD1 4.03Å; W237-I323 HydrophobicContact CZ2-CD1 3.33Å; S241-I323 WeakPolarHBondContact OG-CD1 3.42Å; G319-I323 WeakPolarHBondContact O-CG1 3.42Å; G319-I323 PolarHBondContact O-N 3.33Å; T320-I323 PolarHBondContact O-N 3.49Å; I323-G325 VanDerWaalsContact C-N 3.32Å; I323-G325 PolarHBondContact O-N 3.4Å; I323-G326 PolarHBondContact O-N 3.32Å; I323-G326 VanDerWaalsContact O-N 3.11Å; I323-F327 HydrophobicContact CG2-CD2 3.6Å; I323-F327 HydrophobicContact CG2-CE2 3.8Å; I323-F327 VanDerWaalsContact O-CD2 3.29Å; I323-F327 WeakPolarHBondContact O-CD2 3.12Å; I323-F327 PolarHBondContact O-N 2.94Å; I323-C358 HydrophobicContact CD1-CB 4.04Å; I323-C358 HydrophobicContact CG2-CB 4.38Å; I323-I362 HydrophobicContact CD1-CD1 4.04Å
324	V	95.2	Very high	94.2	Very high	92 Å²	92	52.4 Å²	52.4	56%	0.558	29%	0.286	S	S	*	.	H	α-helix	trans	-57.8	-46.4	179.4	172.1	0	0	0	0	110.8	T320 C321 G326 F327 A328	T320-V324 HydrophobicContact CG2-CG2 4.37Å; T320-V324 WeakPolarHBondContact O-CG2 3.29Å; T320-V324 PolarHBondContact O-N 2.94Å; C321-V324 PolarHBondContact O-N 3.2Å; V324-G326 PolarHBondContact O-N 3.16Å; V324-F327 PolarHBondContact O-N 3.19Å; V324-A328 VanDerWaalsContact O-CB 3.27Å; V324-A328 WeakPolarHBondContact O-CB 3.25Å; V324-A328 PolarHBondContact O-N 2.99Å
325	G	95.3	Very high	93.8	Very high	22 Å²	22	53 Å²	53	23%	0.227	29%	0.289	C	S	.	.	H	α-helix	trans	-63	-39.2	176.1	0	0	0	0	0	113.4	C321 F322 I323 S329	C321-G325 PolarHBondContact O-N 3.32Å; F322-G325 PolarHBondContact O-N 3.1Å; I323-G325 VanDerWaalsContact C-N 3.32Å; I323-G325 PolarHBondContact O-N 3.4Å; G325-S329 WeakPolarHBondContact O-CB 3.04Å; G325-S329 PolarHBondContact O-N 3.25Å; G325-S329 VanDerWaalsContact O-N 3.15Å; G325-S329 PolarHBondContact O-OG 3.3Å
326	G	92.7	Very high	93.5	Very high	0 Å²	0	54 Å²	54	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-66.3	-46.7	177.3	0	0	0	0	0	112	F322 I323 V324 S329 M330	F322-G326 PolarHBondContact O-N 3.23Å; I323-G326 PolarHBondContact O-N 3.32Å; I323-G326 VanDerWaalsContact O-N 3.11Å; V324-G326 PolarHBondContact O-N 3.16Å; G326-S329 PolarHBondContact O-N 3.03Å; G326-M330 WeakPolarHBondContact O-CG 3.49Å; G326-M330 PolarHBondContact O-N 3.43Å
327	F	92.1	Very high	93.1	Very high	39 Å²	39	56.6 Å²	56.6	17%	0.171	31%	0.307	C	S	.	.	H	α-helix	trans	-65.5	-46.2	177.3	-87.3	-79.3	0	0	0	112.8	L244 I323 V324 S329 M330 C331 M351 M354 G355	L244-F327 HydrophobicContact CD2-CD2 4.45Å; L244-F327 HydrophobicContact CD2-CE2 3.94Å; I323-F327 HydrophobicContact CG2-CD2 3.6Å; I323-F327 HydrophobicContact CG2-CE2 3.8Å; I323-F327 VanDerWaalsContact O-CD2 3.29Å; I323-F327 WeakPolarHBondContact O-CD2 3.12Å; I323-F327 PolarHBondContact O-N 2.94Å; V324-F327 PolarHBondContact O-N 3.19Å; F327-S329 PolarHBondContact O-N 3.46Å; F327-M330 HydrophobicContact CD1-CE 3.8Å; F327-M330 HydrophobicContact CD2-CE 4.32Å; F327-M330 HydrophobicContact CE1-CE 3.89Å; F327-M330 HydrophobicContact CE2-CE 4.39Å; F327-M330 HydrophobicContact CG-CE 4Å; F327-M330 HydrophobicContact CZ-CE 4.15Å; F327-M330 PolarHBondContact O-N 3.49Å; F327-C331 WeakPolarHBondContact O-CB 3.33Å; F327-C331 PolarHBondContact O-N 3.38Å; F327-C331 PolarHBondContact O-SG 2.86Å; F327-M351 HydrophobicContact CE1-CB 4.5Å; F327-M351 WeakPolarHBondContact CE1-O 3.31Å; F327-M354 HydrophobicContact CZ-CB 3.82Å; F327-G355 VanDerWaalsContact CZ-N 3.34Å
328	A	93.1	Very high	92.8	Very high	59 Å²	59	60.2 Å²	60.2	49%	0.488	31%	0.312	S	S	.	.	H	α-helix	trans	-55.7	-41.1	175.7	0	0	0	0	0	111.4	V324 R332	V324-A328 VanDerWaalsContact O-CB 3.27Å; V324-A328 WeakPolarHBondContact O-CB 3.25Å; V324-A328 PolarHBondContact O-N 2.99Å; A328-R332 PolarHBondContact O-N 3.43Å
329	S	92.1	Very high	92.5	Very high	31 Å²	31	62.3 Å²	62.3	22%	0.217	33%	0.328	C	S	.	.	H	α-helix	trans	-68.7	-45.3	178.1	-52.9	0	0	0	0	112.5	G248 G249 G325 G326 F327 C331 R332 E333	G248-S329 VanDerWaalsContact O-CB 3.27Å; G248-S329 WeakPolarHBondContact O-CB 3.22Å; G249-S329 WeakPolarHBondContact CA-OG 3.16Å; G325-S329 WeakPolarHBondContact O-CB 3.04Å; G325-S329 PolarHBondContact O-N 3.25Å; G325-S329 VanDerWaalsContact O-N 3.15Å; G325-S329 PolarHBondContact O-OG 3.3Å; G326-S329 PolarHBondContact O-N 3.03Å; F327-S329 PolarHBondContact O-N 3.46Å; S329-C331 VanDerWaalsContact C-N 3.32Å; S329-C331 PolarHBondContact O-N 2.63Å; S329-R332 WeakPolarHBondContact O-CB 3.5Å; S329-R332 PolarHBondContact O-N 2.88Å; S329-E333 WeakPolarHBondContact O-CG 3.12Å; S329-E333 PolarHBondContact O-N 2.98Å
330	M	89.2	Confident	92.2	Very high	17 Å²	17	71 Å²	71	8%	0.084	36%	0.361	C	S	.	.	H	α-helix	trans	-61.9	-39.2	175.7	-71.9	-173.7	-68.4	0	0	112.2	L244 G326 F327 E333 R334 M351	L244-M330 HydrophobicContact CD1-CE 3.95Å; L244-M330 HydrophobicContact CD1-SD 4.33Å; L244-M330 HydrophobicContact CG-CE 4.45Å; G326-M330 WeakPolarHBondContact O-CG 3.49Å; G326-M330 PolarHBondContact O-N 3.43Å; F327-M330 HydrophobicContact CD1-CE 3.8Å; F327-M330 HydrophobicContact CD2-CE 4.32Å; F327-M330 HydrophobicContact CE1-CE 3.89Å; F327-M330 HydrophobicContact CE2-CE 4.39Å; F327-M330 HydrophobicContact CG-CE 4Å; F327-M330 HydrophobicContact CZ-CE 4.15Å; F327-M330 PolarHBondContact O-N 3.49Å; M330-E333 PolarHBondContact O-N 3.28Å; M330-R334 WeakPolarHBondContact O-CB 3.19Å; M330-R334 PolarHBondContact O-N 3.16Å; M330-M351 HydrophobicContact CB-CE 3.84Å; M330-M351 HydrophobicContact CB-CG 4.16Å; M330-M351 HydrophobicContact CB-SD 3.94Å; M330-M351 HydrophobicContact CE-CG 4.42Å; M330-M351 HydrophobicContact SD-CG 4.04Å
331	C	89.9	Confident	92	Very high	57 Å²	57	72.3 Å²	72.3	39%	0.385	38%	0.383	S	S	.	.	H	α-helix	trans	-61.3	-45	174.4	-74	0	0	0	0	111.8	F327 S329 E333 R334 I335 M351	F327-C331 WeakPolarHBondContact O-CB 3.33Å; F327-C331 PolarHBondContact O-N 3.38Å; F327-C331 PolarHBondContact O-SG 2.86Å; S329-C331 VanDerWaalsContact C-N 3.32Å; S329-C331 PolarHBondContact O-N 2.63Å; C331-E333 PolarHBondContact O-N 3.32Å; C331-R334 PolarHBondContact O-N 3.29Å; C331-I335 VanDerWaalsContact O-CG1 3.31Å; C331-I335 WeakPolarHBondContact O-CG1 3.46Å; C331-I335 PolarHBondContact O-N 3.25Å; C331-M351 HydrophobicContact CB-CE 4.37Å; C331-M351 WeakPolarHBondContact SG-CE 3.3Å
332	R	91.6	Very high	91.7	Very high	191 Å²	191	71.9 Å²	71.9	72%	0.721	38%	0.378	S	S	*	.	H	α-helix	trans	-59.1	-46.1	176.9	-176.7	-178.1	178.5	-176.6	1	111.7	A328 S329 I335 S336	A328-R332 PolarHBondContact O-N 3.43Å; S329-R332 WeakPolarHBondContact O-CB 3.5Å; S329-R332 PolarHBondContact O-N 2.88Å; R332-I335 PolarHBondContact O-N 2.99Å; R332-S336 PolarHBondContact O-N 3.48Å
333	E	87.8	Confident	91.3	Very high	46 Å²	46	74.7 Å²	74.7	22%	0.215	40%	0.396	C	S	.	.	H	α-helix	trans	-67.4	-40	178.3	-64.7	-63.3	137.1	0	0	111.9	K251 S329 M330 C331 I335 S336 F337	K251-E333 WeakPolarHBondContact CE-OE1 3.5Å; K251-E333 IonicContact NZ-OE1 2.71Å; K251-E333 PolarHBondContact NZ-OE1 3.17Å; K251-E333 IonicContact NZ-OE2 2.87Å; K251-E333 PolarHBondContact NZ-OE2 3.38Å; S329-E333 WeakPolarHBondContact O-CG 3.12Å; S329-E333 PolarHBondContact O-N 2.98Å; M330-E333 PolarHBondContact O-N 3.28Å; C331-E333 PolarHBondContact O-N 3.32Å; E333-I335 VanDerWaalsContact C-N 3.32Å; E333-I335 PolarHBondContact O-N 3.2Å; E333-S336 WeakPolarHBondContact O-CB 3.39Å; E333-S336 PolarHBondContact O-N 3.46Å; E333-S336 VanDerWaalsContact O-N 3.13Å; E333-F337 HydrophobicContact CB-CE2 4.33Å; E333-F337 VanDerWaalsContact O-CD2 3.26Å; E333-F337 WeakPolarHBondContact O-CD2 3.14Å; E333-F337 PolarHBondContact O-N 3.39Å
334	R	89.3	Confident	90.9	Very high	69 Å²	69	74.9 Å²	74.9	26%	0.26	40%	0.397	S	S	.	.	H	α-helix	trans	-58.8	-43.9	175	-178	-92.8	-172.8	172.8	4.1	111.7	M330 C331 F337 R338 T344 L347 E348 M351	M330-R334 WeakPolarHBondContact O-CB 3.19Å; M330-R334 PolarHBondContact O-N 3.16Å; C331-R334 PolarHBondContact O-N 3.29Å; R334-F337 PolarHBondContact O-N 3.24Å; R334-R338 WeakPolarHBondContact O-CB 3.49Å; R334-R338 PolarHBondContact O-N 3.2Å; R334-T344 HydrophobicContact CG-CG2 4.29Å; R334-L347 HydrophobicContact CB-CD2 3.89Å; R334-L347 HydrophobicContact CG-CD2 4.39Å; R334-E348 HydrophobicContact CG-CG 4.41Å; R334-E348 IonicContact CZ-OE1 3.18Å; R334-E348 IonicContact NE-OE1 2.84Å; R334-E348 PolarHBondContact NE-OE1 3.36Å; R334-E348 IonicContact NH2-OE1 2.69Å; R334-E348 PolarHBondContact NH2-OE1 3.16Å; R334-M351 HydrophobicContact CB-SD 4.38Å
335	I	89.3	Confident	90.6	Very high	100 Å²	100	72.5 Å²	72.5	51%	0.513	39%	0.385	S	S	.	.	H	α-helix	trans	-60.7	-47.5	174.8	-66.9	164.4	0	0	0	109.7	C331 R332 E333 F337 R338 T339	C331-I335 VanDerWaalsContact O-CG1 3.31Å; C331-I335 WeakPolarHBondContact O-CG1 3.46Å; C331-I335 PolarHBondContact O-N 3.25Å; R332-I335 PolarHBondContact O-N 2.99Å; E333-I335 VanDerWaalsContact C-N 3.32Å; E333-I335 PolarHBondContact O-N 3.2Å; I335-F337 PolarHBondContact O-N 3.11Å; I335-R338 PolarHBondContact O-N 3.31Å; I335-T339 PolarHBondContact O-N 3.28Å; I335-T339 PolarHBondContact O-OG1 3.46Å; I335-T339 VanDerWaalsContact O-OG1 3.05Å
336	S	90.1	Very high	90.2	Very high	38 Å²	38	79.7 Å²	79.7	27%	0.266	41%	0.41	S	S	.	.	H	α-helix	trans	-58	-45.5	177.4	175.4	0	0	0	0	113.2	R332 E333 T339 R340	R332-S336 PolarHBondContact O-N 3.48Å; E333-S336 WeakPolarHBondContact O-CB 3.39Å; E333-S336 PolarHBondContact O-N 3.46Å; E333-S336 VanDerWaalsContact O-N 3.13Å; S336-T339 PolarHBondContact O-N 2.91Å; S336-R340 WeakPolarHBondContact O-CG 3.42Å; S336-R340 PolarHBondContact O-N 3.06Å
337	F	89.7	Confident	89.8	Confident	75 Å²	75	81.9 Å²	81.9	33%	0.329	42%	0.422	S	S	.	.	H	α-helix	trans	-66	-39.3	177.7	-74.7	-50.6	0	0	0	112.9	E333 R334 I335 T339 R340 G341 T342 T344 L347	E333-F337 HydrophobicContact CB-CE2 4.33Å; E333-F337 VanDerWaalsContact O-CD2 3.26Å; E333-F337 WeakPolarHBondContact O-CD2 3.14Å; E333-F337 PolarHBondContact O-N 3.39Å; R334-F337 PolarHBondContact O-N 3.24Å; I335-F337 PolarHBondContact O-N 3.11Å; F337-T339 VanDerWaalsContact C-N 3.33Å; F337-R340 CarbonylContact O-C 3.41Å; F337-R340 PolarHBondContact O-N 2.86Å; F337-R340 VanDerWaalsContact O-N 3.13Å; F337-G341 PolarHBondContact O-N 3.09Å; F337-T342 PolarHBondContact O-N 3.04Å; F337-T344 HydrophobicContact CB-CG2 3.68Å; F337-L347 HydrophobicContact CD2-CD2 4.29Å
338	R	89.9	Confident	89.5	Confident	157 Å²	157	83.1 Å²	83.1	59%	0.592	43%	0.428	S	S	*	.	H	α-helix	trans	-64.8	-38.7	176.7	-176.7	168.3	158.3	149.6	-4.6	111.5	R334 I335 R340 G341 T344	R334-R338 WeakPolarHBondContact O-CB 3.49Å; R334-R338 PolarHBondContact O-N 3.2Å; I335-R338 PolarHBondContact O-N 3.31Å; R338-R340 VanDerWaalsContact C-N 3.26Å; R338-R340 PolarHBondContact O-N 3.45Å; R338-G341 PolarHBondContact O-N 3.29Å; R338-T344 HydrophobicContact CB-CG2 4.45Å
339	T	92	Very high	89.3	Confident	117 Å²	117	87.7 Å²	87.7	72%	0.718	44%	0.437	S	S	*	.	H	α-helix	trans	-64	-30.6	172.9	-55.7	0	0	0	0	112.4	I335 S336 F337 G341	I335-T339 PolarHBondContact O-N 3.28Å; I335-T339 PolarHBondContact O-OG1 3.46Å; I335-T339 VanDerWaalsContact O-OG1 3.05Å; S336-T339 PolarHBondContact O-N 2.91Å; F337-T339 VanDerWaalsContact C-N 3.33Å; T339-G341 VanDerWaalsContact C-N 3.3Å; T339-G341 PolarHBondContact O-N 3.23Å
340	R	92	Very high	88.9	Confident	184 Å²	184	89.3 Å²	89.3	69%	0.694	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83	1.9	176	-65.9	175	-174.2	-164.8	-0.9	114.1	S336 F337 R338 T342	S336-R340 WeakPolarHBondContact O-CG 3.42Å; S336-R340 PolarHBondContact O-N 3.06Å; F337-R340 CarbonylContact O-C 3.41Å; F337-R340 PolarHBondContact O-N 2.86Å; F337-R340 VanDerWaalsContact O-N 3.13Å; R338-R340 VanDerWaalsContact C-N 3.26Å; R338-R340 PolarHBondContact O-N 3.45Å; R340-T342 VanDerWaalsContact C-N 3.3Å; R340-T342 PolarHBondContact O-N 3.33Å
341	G	90.4	Very high	88.8	Confident	71 Å²	71	89.5 Å²	89.5	73%	0.732	44%	0.444	S	S	*	.	T	Hydrogen-bonded Turn	trans	71.1	18.8	-178.3	0	0	0	0	0	114.9	F337 R338 T339	F337-G341 PolarHBondContact O-N 3.09Å; R338-G341 PolarHBondContact O-N 3.29Å; T339-G341 VanDerWaalsContact C-N 3.3Å; T339-G341 PolarHBondContact O-N 3.23Å
342	T	91.2	Very high	88.7	Confident	74 Å²	74	92 Å²	92	45%	0.454	46%	0.456	S	S	.	.			trans	-84.7	142.4	177.3	-48.3	0	0	0	0	111	F337 R340 T344	F337-T342 PolarHBondContact O-N 3.04Å; R340-T342 VanDerWaalsContact C-N 3.3Å; R340-T342 PolarHBondContact O-N 3.33Å; T342-T344 PolarHBondContact O-N 3.2Å
343	D	88.6	Confident	88.6	Confident	117 Å²	117	85.3 Å²	85.3	63%	0.626	43%	0.433	S	S	*	.			trans	-65.4	115.5	175.1	177.7	21.6	0	0	0	111.7	S345	D343-S345 VanDerWaalsContact CG-OG 3.3Å; D343-S345 WeakPolarHBondContact OD1-CB 3.4Å; D343-S345 PolarHBondContact OD1-N 3.28Å; D343-S345 PolarHBondContact OD1-OG 3.46Å; D343-S345 PolarHBondContact OD2-OG 3.26Å
344	T	87.9	Confident	88.6	Confident	16 Å²	16	83.3 Å²	83.3	10%	0.098	42%	0.424	C	S	.	.			trans	-96.5	2.8	179	55.7	0	0	0	0	113.8	R334 F337 R338 T342 K346 L347 E348	R334-T344 HydrophobicContact CG-CG2 4.29Å; F337-T344 HydrophobicContact CB-CG2 3.68Å; R338-T344 HydrophobicContact CB-CG2 4.45Å; T342-T344 PolarHBondContact O-N 3.2Å; T344-K346 VanDerWaalsContact C-N 3.29Å; T344-K346 PolarHBondContact O-N 3.33Å; T344-L347 PolarHBondContact O-N 2.83Å; T344-E348 WeakPolarHBondContact O-CG 3.47Å; T344-E348 PolarHBondContact O-N 2.63Å; T344-E348 PolarHBondContact OG1-OE1 2.9Å
345	S	89.1	Confident	88.7	Confident	42 Å²	42	81.2 Å²	81.2	29%	0.294	42%	0.423	S	S	.	.	H	α-helix	trans	-56.2	-38	-172.2	67.4	0	0	0	0	113.9	D343 K349	D343-S345 VanDerWaalsContact CG-OG 3.3Å; D343-S345 WeakPolarHBondContact OD1-CB 3.4Å; D343-S345 PolarHBondContact OD1-N 3.28Å; D343-S345 PolarHBondContact OD1-OG 3.46Å; D343-S345 PolarHBondContact OD2-OG 3.26Å; S345-K349 WeakPolarHBondContact O-CG 3.38Å; S345-K349 PolarHBondContact O-N 3.16Å
346	K	85.6	Confident	88.8	Confident	173 Å²	173	81.2 Å²	81.2	75%	0.752	42%	0.419	S	S	*	.	H	α-helix	trans	-69.3	-43.4	177.1	-67.6	179.6	-176.3	170.4	0	112.1	T344 K349 L350	T344-K346 VanDerWaalsContact C-N 3.29Å; T344-K346 PolarHBondContact O-N 3.33Å; K346-K349 PolarHBondContact O-N 3.34Å; K346-L350 PolarHBondContact O-N 2.9Å; K346-L350 VanDerWaalsContact O-N 3.1Å
347	L	84.3	Confident	88.9	Confident	47 Å²	47	79.4 Å²	79.4	25%	0.246	41%	0.407	C	S	.	.	H	α-helix	trans	-65.1	-41.8	179.2	-178	63.6	0	0	0	110.6	R334 F337 T344 L350 M351	R334-L347 HydrophobicContact CB-CD2 3.89Å; R334-L347 HydrophobicContact CG-CD2 4.39Å; F337-L347 HydrophobicContact CD2-CD2 4.29Å; T344-L347 PolarHBondContact O-N 2.83Å; L347-L350 WeakPolarHBondContact O-CB 3.22Å; L347-L350 PolarHBondContact O-N 3.09Å; L347-M351 HydrophobicContact CD1-CG 4.45Å; L347-M351 HydrophobicContact CD1-SD 4.47Å; L347-M351 HydrophobicContact CG-CG 4.46Å; L347-M351 HydrophobicContact CG-SD 4.01Å; L347-M351 VanDerWaalsContact O-CG 3.29Å; L347-M351 WeakPolarHBondContact O-CG 3.36Å; L347-M351 PolarHBondContact O-N 3.45Å
348	E	87.1	Confident	89	Confident	64 Å²	64	76 Å²	76	30%	0.299	39%	0.392	S	S	.	.	H	α-helix	trans	-62.1	-46.3	177.2	-72.8	175.2	-173	0	0	112.4	R334 T344 L350 M351 V352	R334-E348 HydrophobicContact CG-CG 4.41Å; R334-E348 IonicContact CZ-OE1 3.18Å; R334-E348 IonicContact NE-OE1 2.84Å; R334-E348 PolarHBondContact NE-OE1 3.36Å; R334-E348 IonicContact NH2-OE1 2.69Å; R334-E348 PolarHBondContact NH2-OE1 3.16Å; T344-E348 WeakPolarHBondContact O-CG 3.47Å; T344-E348 PolarHBondContact O-N 2.63Å; T344-E348 PolarHBondContact OG1-OE1 2.9Å; E348-L350 VanDerWaalsContact C-N 3.27Å; E348-L350 PolarHBondContact O-N 3.26Å; E348-M351 PolarHBondContact O-N 2.86Å; E348-V352 WeakPolarHBondContact O-CG2 3.26Å; E348-V352 PolarHBondContact O-N 2.91Å
349	K	87.4	Confident	89.2	Confident	155 Å²	155	71.2 Å²	71.2	67%	0.674	39%	0.387	S	S	*	.	H	α-helix	trans	-58.8	-40.7	174.9	-73.3	173	-177.1	175.7	0	111.8	S345 K346 K353	S345-K349 WeakPolarHBondContact O-CG 3.38Å; S345-K349 PolarHBondContact O-N 3.16Å; K346-K349 PolarHBondContact O-N 3.34Å; K349-K353 VanDerWaalsContact O-CB 3.3Å; K349-K353 WeakPolarHBondContact O-CB 3.38Å; K349-K353 PolarHBondContact O-N 3.37Å; K349-K353 VanDerWaalsContact O-N 3.1Å
350	L	84.4	Confident	89.2	Confident	65 Å²	65	68.3 Å²	68.3	34%	0.34	37%	0.366	S	S	.	.	H	α-helix	trans	-65.9	-46.9	177.3	-175.7	64.2	0	0	0	111.6	K346 L347 E348 K353 M354	K346-L350 PolarHBondContact O-N 2.9Å; K346-L350 VanDerWaalsContact O-N 3.1Å; L347-L350 WeakPolarHBondContact O-CB 3.22Å; L347-L350 PolarHBondContact O-N 3.09Å; E348-L350 VanDerWaalsContact C-N 3.27Å; E348-L350 PolarHBondContact O-N 3.26Å; L350-K353 PolarHBondContact O-N 3.29Å; L350-M354 HydrophobicContact CD1-CE 3.86Å; L350-M354 HydrophobicContact CD1-CG 4.33Å; L350-M354 HydrophobicContact CG-CG 4.43Å; L350-M354 WeakPolarHBondContact O-CB 3.39Å; L350-M354 VanDerWaalsContact O-CG 3.23Å; L350-M354 WeakPolarHBondContact O-CG 3.28Å; L350-M354 PolarHBondContact O-N 2.95Å
351	M	87.5	Confident	89.3	Confident	22 Å²	22	59.9 Å²	59.9	11%	0.108	34%	0.335	C	S	.	.	H	α-helix	trans	-61	-46.4	179	-71.9	173.5	68.9	0	0	111.8	F327 M330 C331 R334 L347 E348 K353 M354 G355	F327-M351 HydrophobicContact CE1-CB 4.5Å; F327-M351 WeakPolarHBondContact CE1-O 3.31Å; M330-M351 HydrophobicContact CB-CE 3.84Å; M330-M351 HydrophobicContact CB-CG 4.16Å; M330-M351 HydrophobicContact CB-SD 3.94Å; M330-M351 HydrophobicContact CE-CG 4.42Å; M330-M351 HydrophobicContact SD-CG 4.04Å; C331-M351 HydrophobicContact CB-CE 4.37Å; C331-M351 WeakPolarHBondContact SG-CE 3.3Å; R334-M351 HydrophobicContact CB-SD 4.38Å; L347-M351 HydrophobicContact CD1-CG 4.45Å; L347-M351 HydrophobicContact CD1-SD 4.47Å; L347-M351 HydrophobicContact CG-CG 4.46Å; L347-M351 HydrophobicContact CG-SD 4.01Å; L347-M351 VanDerWaalsContact O-CG 3.29Å; L347-M351 WeakPolarHBondContact O-CG 3.36Å; L347-M351 PolarHBondContact O-N 3.45Å; E348-M351 PolarHBondContact O-N 2.86Å; M351-K353 PolarHBondContact O-N 3.45Å; M351-M354 PolarHBondContact O-N 3.33Å; M351-G355 PolarHBondContact O-N 3.38Å
352	V	88.2	Confident	89.5	Confident	108 Å²	108	58.4 Å²	58.4	66%	0.655	31%	0.31	S	S	*	.	H	α-helix	trans	-61.1	-45.3	177.5	171.3	0	0	0	0	110.9	E348 G355 F356	E348-V352 WeakPolarHBondContact O-CG2 3.26Å; E348-V352 PolarHBondContact O-N 2.91Å; V352-G355 PolarHBondContact O-N 2.92Å; V352-F356 WeakPolarHBondContact O-CB 2.99Å; V352-F356 PolarHBondContact O-N 3.45Å
353	K	88.6	Confident	89.7	Confident	52 Å²	52	60.3 Å²	60.3	23%	0.226	32%	0.316	C	S	.	.	H	α-helix	trans	-60.1	-49	178.4	-176.8	-176.2	-178.7	-173.4	0	112.1	K349 L350 M351 G355 F357 M423 W424	K349-K353 VanDerWaalsContact O-CB 3.3Å; K349-K353 WeakPolarHBondContact O-CB 3.38Å; K349-K353 PolarHBondContact O-N 3.37Å; K349-K353 VanDerWaalsContact O-N 3.1Å; L350-K353 PolarHBondContact O-N 3.29Å; M351-K353 PolarHBondContact O-N 3.45Å; K353-G355 VanDerWaalsContact C-N 3.32Å; K353-G355 PolarHBondContact O-N 2.87Å; K353-F357 WeakPolarHBondContact O-CB 3.33Å; K353-F357 PolarHBondContact O-N 2.79Å; K353-F357 VanDerWaalsContact O-N 3.08Å; K353-M423 WeakPolarHBondContact CE-O 3.23Å; K353-W424 HydrophobicContact CD-CE3 4.36Å; K353-W424 HydrophobicContact CD-CH2 3.96Å; K353-W424 HydrophobicContact CD-CZ3 3.9Å; K353-W424 HydrophobicContact CG-CH2 4.24Å; K353-W424 HydrophobicContact CG-CZ2 4.43Å
354	M	89	Confident	90.1	Very high	4 Å²	4	55.5 Å²	55.5	2%	0.02	29%	0.292	C	S	.	.	H	α-helix	trans	-62.4	-40.1	177.5	-68.2	-69	-172.7	0	0	111.4	P168 E169 F240 L244 F327 L350 M351 F357 C358 W424	P168-M354 HydrophobicContact CG-CE 3.97Å; E169-M354 HydrophobicContact CG-CE 3.92Å; F240-M354 HydrophobicContact CE2-CE 4.49Å; F240-M354 HydrophobicContact CE2-SD 3.79Å; F240-M354 HydrophobicContact CZ-SD 3.55Å; F240-M354 VanDerWaalsContact CZ-SD 3.55Å; L244-M354 HydrophobicContact CD1-CG 4.5Å; F327-M354 HydrophobicContact CZ-CB 3.82Å; L350-M354 HydrophobicContact CD1-CE 3.86Å; L350-M354 HydrophobicContact CD1-CG 4.33Å; L350-M354 HydrophobicContact CG-CG 4.43Å; L350-M354 WeakPolarHBondContact O-CB 3.39Å; L350-M354 VanDerWaalsContact O-CG 3.23Å; L350-M354 WeakPolarHBondContact O-CG 3.28Å; L350-M354 PolarHBondContact O-N 2.95Å; M351-M354 PolarHBondContact O-N 3.33Å; M354-F357 PolarHBondContact O-N 2.7Å; M354-C358 PolarHBondContact O-N 3.34Å; M354-C358 PolarHBondContact O-SG 3.34Å; M354-W424 HydrophobicContact CE-CH2 3.37Å; M354-W424 HydrophobicContact CE-CZ2 4.08Å; M354-W424 HydrophobicContact CE-CZ3 4.25Å; M354-W424 HydrophobicContact CG-CH2 4.37Å; M354-W424 HydrophobicContact SD-CH2 3.35Å; M354-W424 WeakPolarHBondContact SD-CH2 3.5Å; M354-W424 HydrophobicContact SD-CZ2 3.46Å; M354-W424 WeakPolarHBondContact SD-CZ2 3.17Å
355	G	90.5	Very high	90.5	Very high	24 Å²	24	55.2 Å²	55.2	25%	0.247	29%	0.289	C	S	.	.	H	α-helix	trans	-67.6	-45.3	-176.5	0	0	0	0	0	111.5	F327 M351 V352 K353 C358 A359	F327-G355 VanDerWaalsContact CZ-N 3.34Å; M351-G355 PolarHBondContact O-N 3.38Å; V352-G355 PolarHBondContact O-N 2.92Å; K353-G355 VanDerWaalsContact C-N 3.32Å; K353-G355 PolarHBondContact O-N 2.87Å; G355-C358 PolarHBondContact O-N 2.79Å; G355-A359 PolarHBondContact O-N 2.62Å
356	F	91.3	Very high	90.9	Very high	100 Å²	100	56 Å²	56	44%	0.439	29%	0.292	S	S	.	.	H	α-helix	trans	-65.8	-39.5	176.3	-172.5	-103.4	0	0	0	112.1	V352 C358 A359 L360 M423	V352-F356 WeakPolarHBondContact O-CB 2.99Å; V352-F356 PolarHBondContact O-N 3.45Å; F356-C358 PolarHBondContact O-N 2.72Å; F356-A359 PolarHBondContact O-N 3.21Å; F356-L360 HydrophobicContact CD1-CD1 3.76Å; F356-L360 HydrophobicContact CD1-CG 4.2Å; F356-L360 HydrophobicContact CE1-CD1 3.16Å; F356-L360 HydrophobicContact CE1-CD2 4.48Å; F356-L360 HydrophobicContact CE1-CG 3.82Å; F356-L360 HydrophobicContact CE2-CD1 4.45Å; F356-L360 HydrophobicContact CE2-CD2 4.44Å; F356-L360 HydrophobicContact CE2-CG 4.29Å; F356-L360 HydrophobicContact CZ-CD1 3.58Å; F356-L360 HydrophobicContact CZ-CD2 4.07Å; F356-L360 HydrophobicContact CZ-CG 3.87Å; F356-L360 WeakPolarHBondContact O-CB 3.22Å; F356-L360 WeakPolarHBondContact O-CG 3.06Å; F356-L360 PolarHBondContact O-N 3.02Å; F356-M423 HydrophobicContact CD1-CE 3.6Å; F356-M423 HydrophobicContact CD1-CG 3.48Å; F356-M423 VanDerWaalsContact CD1-CG 3.48Å; F356-M423 HydrophobicContact CD1-SD 3.4Å; F356-M423 WeakPolarHBondContact CD1-SD 3.27Å; F356-M423 HydrophobicContact CE1-CE 4.07Å; F356-M423 HydrophobicContact CE1-CG 3.65Å; F356-M423 HydrophobicContact CE1-SD 3.31Å; F356-M423 WeakPolarHBondContact CE1-SD 3.37Å; F356-M423 HydrophobicContact CG-CE 4.49Å
357	F	92.1	Very high	91.5	Very high	0 Å²	0	51 Å²	51	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-57.1	-48.3	170.9	169.3	-103.4	0	0	0	112.2	V172 L175 F240 K353 M354 A359 L360 F361 S420 W424	V172-F357 HydrophobicContact CG1-CE2 4.33Å; V172-F357 HydrophobicContact CG2-CE1 4.3Å; V172-F357 HydrophobicContact CG2-CE2 4.43Å; V172-F357 HydrophobicContact CG2-CZ 3.98Å; L175-F357 HydrophobicContact CD2-CE2 4.3Å; L175-F357 HydrophobicContact CD2-CZ 3.74Å; F240-F357 HydrophobicContact CD1-CD1 4.41Å; F240-F357 AromaticContact CD1-CE1 3.78Å; F240-F357 HydrophobicContact CD1-CE1 3.78Å; F240-F357 HydrophobicContact CD2-CE1 4.32Å; F240-F357 AromaticContact CE1-CD1 3.69Å; F240-F357 HydrophobicContact CE1-CD1 3.69Å; F240-F357 AromaticContact CE1-CE1 3.51Å; F240-F357 HydrophobicContact CE1-CE1 3.51Å; F240-F357 HydrophobicContact CE2-CD1 4.31Å; F240-F357 HydrophobicContact CE2-CE1 4.07Å; F240-F357 HydrophobicContact CG-CE1 4.18Å; F240-F357 AromaticContact CZ-CD1 3.62Å; F240-F357 HydrophobicContact CZ-CD1 3.62Å; F240-F357 AromaticContact CZ-CE1 3.66Å; F240-F357 HydrophobicContact CZ-CE1 3.66Å; K353-F357 WeakPolarHBondContact O-CB 3.33Å; K353-F357 PolarHBondContact O-N 2.79Å; K353-F357 VanDerWaalsContact O-N 3.08Å; M354-F357 PolarHBondContact O-N 2.7Å; F357-A359 PolarHBondContact O-N 3.25Å; F357-L360 PolarHBondContact O-N 2.91Å; F357-F361 WeakPolarHBondContact O-CB 3.21Å; F357-F361 PolarHBondContact O-N 3.09Å; F357-S420 WeakPolarHBondContact CD2-O 3.29Å; F357-W424 HydrophobicContact CB-CZ2 4.46Å; F357-W424 AromaticContact CD2-CD1 3.83Å; F357-W424 AromaticContact CD2-NE1 3.21Å; F357-W424 AromaticContact CE2-NE1 3.72Å; F357-W424 HydrophobicContact CG-CZ2 4.45Å; F357-W424 AromaticContact CG-NE1 3.42Å
358	C	93	Very high	92.1	Very high	4 Å²	4	49.5 Å²	49.5	3%	0.027	27%	0.265	C	S	.	.	H	α-helix	trans	-61.9	-44.1	178.6	-66.3	0	0	0	0	111.7	I323 M354 G355 F356 F361 I362	I323-C358 HydrophobicContact CD1-CB 4.04Å; I323-C358 HydrophobicContact CG2-CB 4.38Å; M354-C358 PolarHBondContact O-N 3.34Å; M354-C358 PolarHBondContact O-SG 3.34Å; G355-C358 PolarHBondContact O-N 2.79Å; F356-C358 PolarHBondContact O-N 2.72Å; C358-F361 PolarHBondContact O-N 2.76Å; C358-I362 HydrophobicContact CB-CD1 4.44Å; C358-I362 WeakPolarHBondContact O-CB 3.3Å; C358-I362 VanDerWaalsContact O-CG1 3.23Å; C358-I362 WeakPolarHBondContact O-CG1 2.99Å; C358-I362 PolarHBondContact O-N 2.95Å
359	A	92.1	Very high	92.6	Very high	57 Å²	57	47.7 Å²	47.7	47%	0.471	26%	0.257	S	S	.	.	H	α-helix	trans	-63	-46.8	179.3	0	0	0	0	0	112	G355 F356 F357 F361 I362 L363	G355-A359 PolarHBondContact O-N 2.62Å; F356-A359 PolarHBondContact O-N 3.21Å; F357-A359 PolarHBondContact O-N 3.25Å; A359-F361 PolarHBondContact O-N 2.96Å; A359-I362 PolarHBondContact O-N 3.43Å; A359-L363 WeakPolarHBondContact O-CB 3.41Å; A359-L363 PolarHBondContact O-N 3.13Å
360	L	93.1	Very high	93.1	Very high	56 Å²	56	44.8 Å²	44.8	29%	0.293	25%	0.252	S	S	.	.	H	α-helix	trans	-64.9	-24.4	176.9	-74.5	-173.6	0	0	0	113.4	F356 F357 P364 M423	F356-L360 HydrophobicContact CD1-CD1 3.76Å; F356-L360 HydrophobicContact CD1-CG 4.2Å; F356-L360 HydrophobicContact CE1-CD1 3.16Å; F356-L360 HydrophobicContact CE1-CD2 4.48Å; F356-L360 HydrophobicContact CE1-CG 3.82Å; F356-L360 HydrophobicContact CE2-CD1 4.45Å; F356-L360 HydrophobicContact CE2-CD2 4.44Å; F356-L360 HydrophobicContact CE2-CG 4.29Å; F356-L360 HydrophobicContact CZ-CD1 3.58Å; F356-L360 HydrophobicContact CZ-CD2 4.07Å; F356-L360 HydrophobicContact CZ-CG 3.87Å; F356-L360 WeakPolarHBondContact O-CB 3.22Å; F356-L360 WeakPolarHBondContact O-CG 3.06Å; F356-L360 PolarHBondContact O-N 3.02Å; F357-L360 PolarHBondContact O-N 2.91Å; L360-P364 WeakPolarHBondContact O-CD 3.31Å; L360-P364 VanDerWaalsContact O-CG 3.3Å; L360-P364 WeakPolarHBondContact O-CG 3.3Å; L360-M423 HydrophobicContact CD1-CG 4.33Å
361	F	93.4	Very high	93.7	Very high	7 Å²	7	42.4 Å²	42.4	3%	0.031	24%	0.241	C	C	.	.	H	α-helix	trans	-85.5	-46.7	175.1	-169.1	-85	0	0	0	112.3	L175 I179 W237 F357 C358 A359 P364 N365	L175-F361 HydrophobicContact CD1-CE2 3.99Å; L175-F361 HydrophobicContact CD1-CZ 4.34Å; L175-F361 HydrophobicContact CD2-CD2 4.31Å; L175-F361 HydrophobicContact CD2-CE2 4.03Å; L175-F361 HydrophobicContact CG-CE2 4.49Å; I179-F361 HydrophobicContact CD1-CE2 4.47Å; W237-F361 HydrophobicContact CB-CD1 4.28Å; W237-F361 HydrophobicContact CB-CE1 3.57Å; W237-F361 HydrophobicContact CB-CE2 4.31Å; W237-F361 HydrophobicContact CB-CZ 3.58Å; W237-F361 AromaticContact CD1-CD1 3.15Å; W237-F361 AromaticContact CD1-CE1 3.38Å; W237-F361 AromaticContact CD1-CG 3.48Å; W237-F361 VanDerWaalsContact CD1-CG 3.48Å; W237-F361 AromaticContact CD1-CZ 3.91Å; W237-F361 AromaticContact CD2-CD1 3.69Å; W237-F361 HydrophobicContact CD2-CD1 3.69Å; W237-F361 AromaticContact CD2-CE1 3.52Å; W237-F361 HydrophobicContact CD2-CE1 3.52Å; W237-F361 HydrophobicContact CD2-CZ 4.45Å; W237-F361 AromaticContact CE2-CD1 3.54Å; W237-F361 AromaticContact CE2-CE1 3.91Å; W237-F361 HydrophobicContact CE3-CE1 4.22Å; W237-F361 AromaticContact CG-CD1 3.45Å; W237-F361 HydrophobicContact CG-CD1 3.45Å; W237-F361 VanDerWaalsContact CG-CD1 3.45Å; W237-F361 AromaticContact CG-CE1 3.17Å; W237-F361 HydrophobicContact CG-CE1 3.17Å; W237-F361 HydrophobicContact CG-CE2 4.38Å; W237-F361 HydrophobicContact CG-CG 4.16Å; W237-F361 AromaticContact CG-CZ 3.69Å; W237-F361 HydrophobicContact CG-CZ 3.69Å; W237-F361 HydrophobicContact CZ2-CD1 4.34Å; W237-F361 AromaticContact NE1-CD1 3.19Å; W237-F361 AromaticContact NE1-CE1 3.8Å; W237-F361 AromaticContact NE1-CG 3.65Å; F357-F361 WeakPolarHBondContact O-CB 3.21Å; F357-F361 PolarHBondContact O-N 3.09Å; C358-F361 PolarHBondContact O-N 2.76Å; A359-F361 PolarHBondContact O-N 2.96Å; F361-P364 WeakPolarHBondContact O-CD 3.28Å; F361-N365 WeakPolarHBondContact CD1-ND2 3.09Å; F361-N365 WeakPolarHBondContact CE1-ND2 3.44Å; F361-N365 PolarHBondContact O-ND2 3.2Å
362	I	95.2	Very high	94.1	Very high	39 Å²	39	42.5 Å²	42.5	20%	0.2	24%	0.241	C	C	.	.	H	α-helix	trans	-65.5	-45	-176.3	-68.6	166.3	0	0	0	110.8	W237 I323 C358 A359 N365 V366	W237-I362 HydrophobicContact CH2-CD1 4.43Å; W237-I362 HydrophobicContact CH2-CG1 4.06Å; W237-I362 HydrophobicContact CZ2-CD1 3.88Å; W237-I362 HydrophobicContact CZ2-CG1 3.46Å; W237-I362 VanDerWaalsContact CZ2-CG1 3.46Å; I323-I362 HydrophobicContact CD1-CD1 4.04Å; C358-I362 HydrophobicContact CB-CD1 4.44Å; C358-I362 WeakPolarHBondContact O-CB 3.3Å; C358-I362 VanDerWaalsContact O-CG1 3.23Å; C358-I362 WeakPolarHBondContact O-CG1 2.99Å; C358-I362 PolarHBondContact O-N 2.95Å; A359-I362 PolarHBondContact O-N 3.43Å; I362-N365 PolarHBondContact O-N 3.05Å; I362-V366 HydrophobicContact CG2-CG2 3.8Å; I362-V366 WeakPolarHBondContact O-CG2 3.05Å; I362-V366 PolarHBondContact O-N 3.3Å
363	L	96.2	Very high	94.6	Very high	114 Å²	114	40 Å²	40	60%	0.597	23%	0.228	S	C	*	.	H	α-helix	trans	-58	-52.1	-172.4	176.4	70.8	0	0	0	112.6	A359 N365 V366 I367	A359-L363 WeakPolarHBondContact O-CB 3.41Å; A359-L363 PolarHBondContact O-N 3.13Å; L363-N365 VanDerWaalsContact C-N 3.35Å; L363-N365 PolarHBondContact O-N 3.46Å; L363-V366 PolarHBondContact O-N 3.05Å; L363-I367 HydrophobicContact CD1-CD1 4.17Å; L363-I367 HydrophobicContact CG-CD1 4.11Å; L363-I367 WeakPolarHBondContact O-CG1 3.47Å; L363-I367 PolarHBondContact O-N 3.06Å; L363-I367 VanDerWaalsContact O-N 3.09Å
364	P	96.5	Very high	95	Very high	17 Å²	17	40.5 Å²	40.5	11%	0.11	23%	0.228	C	C	.	.	H	α-helix	trans	-63.7	-36.9	176.1	-21.1	32.9	0	0	0	113.5	L360 F361 V366 I367 E368 S413 A416 T417	L360-P364 WeakPolarHBondContact O-CD 3.31Å; L360-P364 VanDerWaalsContact O-CG 3.3Å; L360-P364 WeakPolarHBondContact O-CG 3.3Å; F361-P364 WeakPolarHBondContact O-CD 3.28Å; P364-V366 PolarHBondContact O-N 3.04Å; P364-I367 PolarHBondContact O-N 2.04Å; P364-E368 WeakPolarHBondContact O-CB 3.45Å; P364-E368 PolarHBondContact O-N 2.83Å; P364-S413 VanDerWaalsContact CB-O 3.22Å; P364-S413 WeakPolarHBondContact CB-O 3.44Å; P364-S413 WeakPolarHBondContact O-CB 3.42Å; P364-A416 HydrophobicContact CB-CB 4.12Å; P364-A416 HydrophobicContact CG-CB 4.14Å; P364-T417 HydrophobicContact CB-CG2 4.26Å
365	N	95.8	Very high	95.3	Very high	9 Å²	9	41 Å²	41	5%	0.048	23%	0.231	C	C	.	.	H	α-helix	trans	-68.5	-33.1	179.9	-81.7	-82.5	0	0	0	112.9	R312 I316 F361 I362 L363 L369 T417	R312-N365 PolarHBondContact NH1-OD1 2.9Å; I316-N365 HydrophobicContact CD1-CB 4.01Å; F361-N365 WeakPolarHBondContact CD1-ND2 3.09Å; F361-N365 WeakPolarHBondContact CE1-ND2 3.44Å; F361-N365 PolarHBondContact O-ND2 3.2Å; I362-N365 PolarHBondContact O-N 3.05Å; L363-N365 VanDerWaalsContact C-N 3.35Å; L363-N365 PolarHBondContact O-N 3.46Å; N365-L369 WeakPolarHBondContact O-CB 3.26Å; N365-L369 PolarHBondContact O-N 2.84Å; N365-T417 VanDerWaalsContact ND2-CG2 3.3Å; N365-T417 WeakPolarHBondContact ND2-CG2 3.17Å
366	V	97.4	Very high	95.5	Very high	59 Å²	59	42.2 Å²	42.2	36%	0.358	23%	0.229	S	C	.	.	H	α-helix	trans	-71.4	-43.4	173.7	171.1	0	0	0	0	110.6	I316 I362 L363 P364 E368 L369 V370	I316-V366 HydrophobicContact CG2-CG2 4.28Å; I362-V366 HydrophobicContact CG2-CG2 3.8Å; I362-V366 WeakPolarHBondContact O-CG2 3.05Å; I362-V366 PolarHBondContact O-N 3.3Å; L363-V366 PolarHBondContact O-N 3.05Å; P364-V366 PolarHBondContact O-N 3.04Å; V366-E368 VanDerWaalsContact C-N 3.31Å; V366-E368 PolarHBondContact O-N 2.85Å; V366-L369 WeakPolarHBondContact O-CB 3.48Å; V366-L369 PolarHBondContact O-N 2.85Å; V366-V370 WeakPolarHBondContact O-CG2 3.42Å; V366-V370 PolarHBondContact O-N 3.26Å
367	I	97.9	Very high	95.6	Very high	68 Å²	68	43.4 Å²	43.4	35%	0.349	24%	0.238	S	C	.	.	H	α-helix	trans	-57.9	-47.6	173.9	-67.6	165.7	0	0	0	109.9	L363 P364 L369 V370 C371 T409	L363-I367 HydrophobicContact CD1-CD1 4.17Å; L363-I367 HydrophobicContact CG-CD1 4.11Å; L363-I367 WeakPolarHBondContact O-CG1 3.47Å; L363-I367 PolarHBondContact O-N 3.06Å; L363-I367 VanDerWaalsContact O-N 3.09Å; P364-I367 PolarHBondContact O-N 2.04Å; I367-L369 VanDerWaalsContact C-N 3.34Å; I367-L369 PolarHBondContact O-N 3.25Å; I367-V370 PolarHBondContact O-N 3.4Å; I367-C371 PolarHBondContact O-N 3.2Å; I367-C371 PolarHBondContact O-SG 3.49Å; I367-T409 HydrophobicContact CG2-CG2 3.79Å
368	E	96.9	Very high	95.6	Very high	16 Å²	16	45 Å²	45	8%	0.075	25%	0.245	C	C	.	.	H	α-helix	trans	-56.1	-48.3	176.3	-165.8	-179	162.2	0	0	111.3	R312 P364 V366 V370 C371 Q372 S413 S414	R312-E368 IonicContact CZ-OE1 3.67Å; R312-E368 IonicContact CZ-OE2 3.44Å; R312-E368 IonicContact NH1-OE1 3.14Å; R312-E368 IonicContact NH1-OE2 2.9Å; R312-E368 PolarHBondContact NH1-OE2 3.12Å; R312-E368 IonicContact NH2-OE1 3.8Å; R312-E368 PolarHBondContact NH2-OE1 3.35Å; R312-E368 IonicContact NH2-OE2 2.63Å; R312-E368 PolarHBondContact NH2-OE2 2.91Å; P364-E368 WeakPolarHBondContact O-CB 3.45Å; P364-E368 PolarHBondContact O-N 2.83Å; V366-E368 VanDerWaalsContact C-N 3.31Å; V366-E368 PolarHBondContact O-N 2.85Å; E368-V370 VanDerWaalsContact C-N 3.34Å; E368-V370 PolarHBondContact O-N 2.85Å; E368-C371 PolarHBondContact O-N 2.87Å; E368-Q372 WeakPolarHBondContact O-CG 3.43Å; E368-Q372 PolarHBondContact O-N 2.89Å; E368-S413 WeakPolarHBondContact CA-OG 3.03Å; E368-S413 VanDerWaalsContact CB-OG 3.27Å; E368-S413 WeakPolarHBondContact CB-OG 3.05Å; E368-S413 PolarHBondContact N-OG 2.84Å; E368-S414 VanDerWaalsContact CD-CB 3.45Å; E368-S414 WeakPolarHBondContact OE2-CA 3.02Å; E368-S414 VanDerWaalsContact OE2-CB 3.29Å; E368-S414 WeakPolarHBondContact OE2-CB 3.35Å
369	L	97.5	Very high	95.5	Very high	26 Å²	26	44.8 Å²	44.8	14%	0.136	24%	0.244	C	C	.	.	H	α-helix	trans	-58.4	-44.5	179.1	179.2	62.5	0	0	0	112	I309 T313 I316 N365 V366 I367 C371 Q372 C373	I309-L369 HydrophobicContact CG2-CD1 4.08Å; T313-L369 WeakPolarHBondContact OG1-CD1 3.21Å; I316-L369 HydrophobicContact CD1-CD2 4.3Å; N365-L369 WeakPolarHBondContact O-CB 3.26Å; N365-L369 PolarHBondContact O-N 2.84Å; V366-L369 WeakPolarHBondContact O-CB 3.48Å; V366-L369 PolarHBondContact O-N 2.85Å; I367-L369 VanDerWaalsContact C-N 3.34Å; I367-L369 PolarHBondContact O-N 3.25Å; L369-C371 VanDerWaalsContact C-N 3.34Å; L369-C371 PolarHBondContact O-N 3.5Å; L369-Q372 PolarHBondContact O-N 2.88Å; L369-C373 PolarHBondContact O-N 2.01Å; L369-C373 PolarHBondContact O-SG 3.27Å; L369-C373 VanDerWaalsContact O-SG 3.36Å
370	V	98.1	Very high	95.4	Very high	94 Å²	94	43.6 Å²	43.6	57%	0.57	23%	0.231	S	C	*	.	H	α-helix	trans	-61	-44.2	176.7	172.9	0	0	0	0	110.8	V366 I367 E368 Q372 C373 Y374	V366-V370 WeakPolarHBondContact O-CG2 3.42Å; V366-V370 PolarHBondContact O-N 3.26Å; I367-V370 PolarHBondContact O-N 3.4Å; E368-V370 VanDerWaalsContact C-N 3.34Å; E368-V370 PolarHBondContact O-N 2.85Å; V370-Q372 VanDerWaalsContact C-N 3.34Å; V370-Q372 PolarHBondContact O-N 3.49Å; V370-C373 WeakPolarHBondContact O-CB 3.26Å; V370-C373 PolarHBondContact O-N 3.02Å; V370-Y374 PolarHBondContact O-N 3.47Å
371	C	97.7	Very high	95.2	Very high	14 Å²	14	45.6 Å²	45.6	10%	0.095	24%	0.239	C	C	.	.	H	α-helix	trans	-63.9	-36.4	175.8	-62.6	0	0	0	0	112.5	I367 E368 L369 Y374 K375 I406 A410	I367-C371 PolarHBondContact O-N 3.2Å; I367-C371 PolarHBondContact O-SG 3.49Å; E368-C371 PolarHBondContact O-N 2.87Å; L369-C371 VanDerWaalsContact C-N 3.34Å; L369-C371 PolarHBondContact O-N 3.5Å; C371-Y374 WeakPolarHBondContact O-CB 3.5Å; C371-Y374 PolarHBondContact O-N 3.49Å; C371-K375 PolarHBondContact O-N 2.94Å; C371-I406 HydrophobicContact CB-CG2 4.1Å; C371-A410 HydrophobicContact CB-CB 3.57Å
372	Q	96.8	Very high	94.8	Very high	25 Å²	25	45.9 Å²	45.9	12%	0.117	24%	0.24	C	C	.	.	H	α-helix	trans	-68.8	-36.5	175.2	-63.5	-61.4	-11.9	0	0	112.1	I309 E368 L369 V370 Y374 K375 F376	I309-Q372 HydrophobicContact CD1-CB 4.35Å; I309-Q372 HydrophobicContact CG1-CB 4.04Å; E368-Q372 WeakPolarHBondContact O-CG 3.43Å; E368-Q372 PolarHBondContact O-N 2.89Å; L369-Q372 PolarHBondContact O-N 2.88Å; V370-Q372 VanDerWaalsContact C-N 3.34Å; V370-Q372 PolarHBondContact O-N 3.49Å; Q372-Y374 VanDerWaalsContact C-N 3.34Å; Q372-K375 WeakPolarHBondContact O-CB 3.36Å; Q372-K375 PolarHBondContact O-N 3.39Å; Q372-K375 VanDerWaalsContact OE1-CD 3.29Å; Q372-F376 PolarHBondContact O-N 2.97Å
373	C	97.6	Very high	94.2	Very high	55 Å²	55	45.5 Å²	45.5	37%	0.372	24%	0.24	S	C	.	.	H	α-helix	trans	-62.1	-42.2	172	-69.9	0	0	0	0	111.4	L369 V370 F376 M377	L369-C373 PolarHBondContact O-N 2.01Å; L369-C373 PolarHBondContact O-SG 3.27Å; L369-C373 VanDerWaalsContact O-SG 3.36Å; V370-C373 WeakPolarHBondContact O-CB 3.26Å; V370-C373 PolarHBondContact O-N 3.02Å; C373-F376 WeakPolarHBondContact O-CB 3.24Å; C373-F376 PolarHBondContact O-N 2.94Å; C373-M377 WeakPolarHBondContact O-CG 3.26Å; C373-M377 PolarHBondContact O-N 3.39Å; C373-M377 VanDerWaalsContact O-N 3.1Å
374	Y	96.3	Very high	93.5	Very high	62 Å²	62	48.1 Å²	48.1	24%	0.243	24%	0.242	C	C	.	.	H	α-helix	trans	-59.3	-48.3	171.8	170.7	-96.4	0	0	0	111.7	V370 C371 Q372 F376 M377 I378 I406 Y407	V370-Y374 PolarHBondContact O-N 3.47Å; C371-Y374 WeakPolarHBondContact O-CB 3.5Å; C371-Y374 PolarHBondContact O-N 3.49Å; Q372-Y374 VanDerWaalsContact C-N 3.34Å; Y374-F376 VanDerWaalsContact C-N 3.28Å; Y374-F376 PolarHBondContact O-N 2.64Å; Y374-M377 PolarHBondContact O-N 3.36Å; Y374-M377 VanDerWaalsContact O-N 3.16Å; Y374-I378 HydrophobicContact CD1-CG1 4.23Å; Y374-I378 HydrophobicContact CD2-CG1 4.31Å; Y374-I378 HydrophobicContact CE1-CG1 3.78Å; Y374-I378 HydrophobicContact CE2-CD1 4.03Å; Y374-I378 HydrophobicContact CE2-CG1 3.84Å; Y374-I378 HydrophobicContact CG-CG1 4.49Å; Y374-I378 WeakPolarHBondContact O-CG1 2.98Å; Y374-I378 PolarHBondContact O-N 3.43Å; Y374-I406 HydrophobicContact CD1-CB 4.05Å; Y374-I406 HydrophobicContact CD1-CD1 4.07Å; Y374-I406 HydrophobicContact CD1-CG2 3.47Å; Y374-I406 VanDerWaalsContact CD1-CG2 3.47Å; Y374-I406 HydrophobicContact CD2-CD1 4.21Å; Y374-I406 HydrophobicContact CE1-CB 3.96Å; Y374-I406 HydrophobicContact CE1-CD1 3.74Å; Y374-I406 HydrophobicContact CE1-CG1 4.41Å; Y374-I406 HydrophobicContact CE1-CG2 3.94Å; Y374-I406 HydrophobicContact CE2-CD1 3.92Å; Y374-I406 HydrophobicContact CG-CD1 4.27Å; Y374-I406 HydrophobicContact CG-CG2 4.02Å; Y374-Y407 HydrophobicContact CD1-CE2 4.3Å; Y374-Y407 HydrophobicContact CE1-CD2 4.38Å; Y374-Y407 AromaticContact CE1-CE2 3.93Å; Y374-Y407 HydrophobicContact CE1-CE2 3.93Å
375	K	95.3	Very high	92.5	Very high	15 Å²	15	51.1 Å²	51.1	7%	0.065	26%	0.255	C	S	.	.	H	α-helix	trans	-55.7	-41.8	175.2	179	-174.8	-173.3	-162.5	0	111.9	G297 N298 L304 C371 Q372 I378 L379 Y407	G297-K375 WeakPolarHBondContact O-CE 3.37Å; G297-K375 PolarHBondContact O-NZ 3.36Å; N298-K375 PolarHBondContact OD1-NZ 2.89Å; L304-K375 HydrophobicContact CD1-CD 4.37Å; L304-K375 HydrophobicContact CD2-CB 4.15Å; L304-K375 HydrophobicContact CD2-CD 3.77Å; L304-K375 HydrophobicContact CD2-CG 3.73Å; C371-K375 PolarHBondContact O-N 2.94Å; Q372-K375 WeakPolarHBondContact O-CB 3.36Å; Q372-K375 PolarHBondContact O-N 3.39Å; Q372-K375 VanDerWaalsContact OE1-CD 3.29Å; K375-I378 PolarHBondContact O-N 3.47Å; K375-L379 HydrophobicContact CD-CD1 4.44Å; K375-L379 HydrophobicContact CG-CD1 3.86Å; K375-L379 HydrophobicContact CG-CG 4.22Å; K375-L379 WeakPolarHBondContact O-CB 3.42Å; K375-L379 VanDerWaalsContact O-CG 3.31Å; K375-L379 WeakPolarHBondContact O-CG 3.34Å; K375-L379 PolarHBondContact O-N 3.34Å; K375-Y407 HydrophobicContact CB-CE1 4.23Å; K375-Y407 HydrophobicContact CD-CD1 4.45Å; K375-Y407 HydrophobicContact CD-CE1 3.87Å; K375-Y407 HydrophobicContact CG-CE1 3.61Å
376	F	96.1	Very high	91.4	Very high	50 Å²	50	51 Å²	51	22%	0.219	25%	0.254	C	S	.	.	H	α-helix	trans	-61.3	-45.3	177.1	170.6	-98.8	0	0	0	112.5	S301 L304 L305 I309 Q372 C373 Y374 T380	S301-F376 WeakPolarHBondContact O-CD2 3.17Å; S301-F376 WeakPolarHBondContact O-CE2 3.1Å; L304-F376 HydrophobicContact CD2-CB 3.98Å; L305-F376 HydrophobicContact CB-CD2 4.11Å; L305-F376 HydrophobicContact CB-CE2 3.85Å; L305-F376 HydrophobicContact CD2-CE2 4.17Å; L305-F376 HydrophobicContact CD2-CZ 4.25Å; L305-F376 HydrophobicContact CG-CE2 4.41Å; I309-F376 HydrophobicContact CD1-CB 3.76Å; I309-F376 HydrophobicContact CD1-CG 4.31Å; Q372-F376 PolarHBondContact O-N 2.97Å; C373-F376 WeakPolarHBondContact O-CB 3.24Å; C373-F376 PolarHBondContact O-N 2.94Å; Y374-F376 VanDerWaalsContact C-N 3.28Å; Y374-F376 PolarHBondContact O-N 2.64Å; F376-T380 WeakPolarHBondContact O-CB 3.03Å; F376-T380 PolarHBondContact O-N 2.02Å; F376-T380 PolarHBondContact O-OG1 2.74Å
377	M	93.8	Very high	90.3	Very high	125 Å²	125	50.1 Å²	50.1	62%	0.616	25%	0.247	S	C	*	.	H	α-helix	trans	-62	-47.7	177.5	-66.1	-62.1	-70.9	0	0	111.2	C373 Y374 T380 Q381	C373-M377 WeakPolarHBondContact O-CG 3.26Å; C373-M377 PolarHBondContact O-N 3.39Å; C373-M377 VanDerWaalsContact O-N 3.1Å; Y374-M377 PolarHBondContact O-N 3.36Å; Y374-M377 VanDerWaalsContact O-N 3.16Å; M377-T380 PolarHBondContact O-N 3.23Å; M377-Q381 PolarHBondContact O-N 2.91Å; M377-Q381 VanDerWaalsContact O-N 3.09Å
378	I	92	Very high	89.1	Confident	32 Å²	32	49.8 Å²	49.8	16%	0.164	25%	0.246	C	C	.	.	H	α-helix	trans	-60.9	-51.7	177.9	-69.8	-59.2	0	0	0	111.4	Y374 K375 T380 Q381 W382 P402	Y374-I378 HydrophobicContact CD1-CG1 4.23Å; Y374-I378 HydrophobicContact CD2-CG1 4.31Å; Y374-I378 HydrophobicContact CE1-CG1 3.78Å; Y374-I378 HydrophobicContact CE2-CD1 4.03Å; Y374-I378 HydrophobicContact CE2-CG1 3.84Å; Y374-I378 HydrophobicContact CG-CG1 4.49Å; Y374-I378 WeakPolarHBondContact O-CG1 2.98Å; Y374-I378 PolarHBondContact O-N 3.43Å; K375-I378 PolarHBondContact O-N 3.47Å; I378-T380 VanDerWaalsContact C-N 3.28Å; I378-T380 PolarHBondContact O-N 3.21Å; I378-Q381 PolarHBondContact O-N 2.99Å; I378-W382 WeakPolarHBondContact O-CB 3.44Å; I378-W382 PolarHBondContact O-N 2.6Å; I378-P402 HydrophobicContact CG2-CB 3.97Å
379	L	90.5	Very high	88	Confident	1 Å²	1	50.1 Å²	50.1	1%	0.005	25%	0.25	C	C	.	.	H	α-helix	trans	-60.4	-40.4	-179.3	-74.7	176.5	0	0	0	111.3	M127 L304 K375 Q381 W382 T383	M127-L379 HydrophobicContact CE-CD2 4.01Å; M127-L379 HydrophobicContact SD-CD2 4.12Å; L304-L379 HydrophobicContact CD2-CD1 4.03Å; K375-L379 HydrophobicContact CD-CD1 4.44Å; K375-L379 HydrophobicContact CG-CD1 3.86Å; K375-L379 HydrophobicContact CG-CG 4.22Å; K375-L379 WeakPolarHBondContact O-CB 3.42Å; K375-L379 VanDerWaalsContact O-CG 3.31Å; K375-L379 WeakPolarHBondContact O-CG 3.34Å; K375-L379 PolarHBondContact O-N 3.34Å; L379-Q381 PolarHBondContact O-N 3.13Å; L379-W382 PolarHBondContact O-N 2.56Å; L379-T383 VanDerWaalsContact O-CB 3.27Å; L379-T383 WeakPolarHBondContact O-CB 3.45Å; L379-T383 PolarHBondContact O-N 3.04Å; L379-T383 PolarHBondContact O-OG1 3.17Å
380	T	90.3	Very high	86.5	Confident	32 Å²	32	50.9 Å²	50.9	20%	0.196	25%	0.252	C	S	.	.	H	α-helix	trans	-64.3	-39.9	179.4	-57.8	0	0	0	0	112.2	S301 F376 M377 I378 R384	S301-T380 WeakPolarHBondContact CB-OG1 3.3Å; F376-T380 WeakPolarHBondContact O-CB 3.03Å; F376-T380 PolarHBondContact O-N 2.02Å; F376-T380 PolarHBondContact O-OG1 2.74Å; M377-T380 PolarHBondContact O-N 3.23Å; I378-T380 VanDerWaalsContact C-N 3.28Å; I378-T380 PolarHBondContact O-N 3.21Å; T380-R384 WeakPolarHBondContact O-CD 3.27Å; T380-R384 WeakPolarHBondContact O-CG 2.95Å
381	Q	88.2	Confident	85	Confident	97 Å²	97	53.6 Å²	53.6	45%	0.453	26%	0.259	S	S	.	.	H	α-helix	trans	-73.9	-46.5	176.2	-177.5	177.7	-4.7	0	0	111.8	M377 I378 L379 R384 M385	M377-Q381 PolarHBondContact O-N 2.91Å; M377-Q381 VanDerWaalsContact O-N 3.09Å; I378-Q381 PolarHBondContact O-N 2.99Å; L379-Q381 PolarHBondContact O-N 3.13Å; Q381-R384 PolarHBondContact O-N 3.21Å; Q381-M385 HydrophobicContact CG-CE 3.92Å; Q381-M385 HydrophobicContact CG-SD 3.74Å; Q381-M385 WeakPolarHBondContact O-CG 3.2Å; Q381-M385 PolarHBondContact O-N 3.31Å; Q381-M385 VanDerWaalsContact O-N 3.15Å
382	W	85.6	Confident	83.5	Confident	14 Å²	14	60.5 Å²	60.5	5%	0.053	29%	0.29	C	S	.	.	H	α-helix	trans	-64	-49.1	-174.4	-166.3	96.5	0	0	0	110.8	F120 V126 M127 I378 L379 R384 M385 T386 I387 P399	F120-W382 AromaticContact CE1-CH2 3.77Å; F120-W382 HydrophobicContact CE1-CH2 3.77Å; F120-W382 AromaticContact CE1-CZ3 3.8Å; F120-W382 HydrophobicContact CE1-CZ3 3.8Å; F120-W382 HydrophobicContact CE2-CH2 4.34Å; F120-W382 HydrophobicContact CE2-CZ3 4.47Å; F120-W382 HydrophobicContact CZ-CE3 4.43Å; F120-W382 AromaticContact CZ-CH2 3.39Å; F120-W382 HydrophobicContact CZ-CH2 3.39Å; F120-W382 HydrophobicContact CZ-CZ2 4.49Å; F120-W382 AromaticContact CZ-CZ3 3.35Å; F120-W382 HydrophobicContact CZ-CZ3 3.35Å; V126-W382 HydrophobicContact CG1-CH2 3.39Å; V126-W382 HydrophobicContact CG1-CZ2 3.57Å; M127-W382 HydrophobicContact CG-CD2 4.35Å; M127-W382 HydrophobicContact CG-CH2 4.35Å; M127-W382 HydrophobicContact CG-CZ2 4Å; I378-W382 WeakPolarHBondContact O-CB 3.44Å; I378-W382 PolarHBondContact O-N 2.6Å; L379-W382 PolarHBondContact O-N 2.56Å; W382-R384 VanDerWaalsContact C-N 3.29Å; W382-R384 PolarHBondContact O-N 3.14Å; W382-M385 PolarHBondContact O-N 3.43Å; W382-M385 VanDerWaalsContact O-N 3.08Å; W382-T386 HydrophobicContact CD2-CG2 3.89Å; W382-T386 HydrophobicContact CE3-CG2 4.42Å; W382-T386 HydrophobicContact CG-CG2 4.24Å; W382-T386 HydrophobicContact CH2-CG2 4.34Å; W382-T386 VanDerWaalsContact CH2-OG1 3.26Å; W382-T386 WeakPolarHBondContact CH2-OG1 3.39Å; W382-T386 HydrophobicContact CZ2-CG2 3.84Å; W382-T386 WeakPolarHBondContact CZ3-OG1 3.19Å; W382-T386 PolarHBondContact O-N 3.07Å; W382-T386 PolarHBondContact O-OG1 3.34Å; W382-I387 HydrophobicContact CZ3-CD1 3.88Å; W382-I387 HydrophobicContact CZ3-CG1 4Å; W382-P399 HydrophobicContact CB-CG 4.46Å; W382-P399 HydrophobicContact CG-CG 4.26Å
383	T	82.5	Confident	81.8	Confident	31 Å²	31	62.4 Å²	62.4	19%	0.19	31%	0.306	C	S	.	.	H	α-helix	trans	-55.2	-43.7	178.6	-62.4	0	0	0	0	112.2	L379 M385 I387 D388	L379-T383 VanDerWaalsContact O-CB 3.27Å; L379-T383 WeakPolarHBondContact O-CB 3.45Å; L379-T383 PolarHBondContact O-N 3.04Å; L379-T383 PolarHBondContact O-OG1 3.17Å; T383-M385 PolarHBondContact O-N 2.71Å; T383-I387 HydrophobicContact CG2-CB 4.45Å; T383-I387 HydrophobicContact CG2-CD1 4.24Å; T383-I387 WeakPolarHBondContact O-CB 3.23Å; T383-I387 PolarHBondContact O-N 2.89Å; T383-D388 PolarHBondContact O-N 3.48Å
384	R	80.4	Confident	80	Confident	169 Å²	169	61.7 Å²	61.7	64%	0.638	31%	0.307	S	S	*	.	I	π-helix	trans	-63.5	-42.5	177.7	-70.6	177.5	-178.7	177.1	1.4	112.6	T380 Q381 W382 C389	T380-R384 WeakPolarHBondContact O-CD 3.27Å; T380-R384 WeakPolarHBondContact O-CG 2.95Å; Q381-R384 PolarHBondContact O-N 3.21Å; W382-R384 VanDerWaalsContact C-N 3.29Å; W382-R384 PolarHBondContact O-N 3.14Å; R384-C389 PolarHBondContact O-N 3.38Å
385	M	76.1	Confident	78.4	Confident	80 Å²	80	63.9 Å²	63.9	39%	0.394	34%	0.339	S	S	.	.	I	π-helix	trans	-84.4	-21.5	-172.9	-67.4	-179	173.2	0	0	113.9	Q381 W382 T383 P399	Q381-M385 HydrophobicContact CG-CE 3.92Å; Q381-M385 HydrophobicContact CG-SD 3.74Å; Q381-M385 WeakPolarHBondContact O-CG 3.2Å; Q381-M385 PolarHBondContact O-N 3.31Å; Q381-M385 VanDerWaalsContact O-N 3.15Å; W382-M385 PolarHBondContact O-N 3.43Å; W382-M385 VanDerWaalsContact O-N 3.08Å; T383-M385 PolarHBondContact O-N 2.71Å; M385-P399 HydrophobicContact CB-CG 4.24Å; M385-P399 HydrophobicContact SD-CB 4.09Å; M385-P399 HydrophobicContact SD-CG 4.22Å
386	T	73.3	Confident	77.2	Confident	6 Å²	6	65 Å²	65	4%	0.037	35%	0.348	C	S	.	.	I	π-helix	trans	-115.6	-37.2	-174.7	63.7	0	0	0	0	114.7	W382 K390 R398 P399	W382-T386 HydrophobicContact CD2-CG2 3.89Å; W382-T386 HydrophobicContact CE3-CG2 4.42Å; W382-T386 HydrophobicContact CG-CG2 4.24Å; W382-T386 HydrophobicContact CH2-CG2 4.34Å; W382-T386 VanDerWaalsContact CH2-OG1 3.26Å; W382-T386 WeakPolarHBondContact CH2-OG1 3.39Å; W382-T386 HydrophobicContact CZ2-CG2 3.84Å; W382-T386 WeakPolarHBondContact CZ3-OG1 3.19Å; W382-T386 PolarHBondContact O-N 3.07Å; W382-T386 PolarHBondContact O-OG1 3.34Å; T386-K390 WeakPolarHBondContact O-CD 3.46Å; T386-K390 VanDerWaalsContact O-CG 3.28Å; T386-K390 WeakPolarHBondContact O-CG 3.28Å; T386-R398 HydrophobicContact CG2-CB 4.47Å; T386-R398 HydrophobicContact CG2-CG 4.09Å; T386-P399 HydrophobicContact CG2-CG 4.44Å
387	I	73.1	Confident	76	Confident	40 Å²	40	70.1 Å²	70.1	21%	0.205	37%	0.372	C	S	.	.	I	π-helix	trans	-95.4	-61	-178.2	-61.4	170.1	0	0	0	108.9	L106 F120 W382 T383 C389 K390 Q391	L106-I387 HydrophobicContact CD1-CG1 4.42Å; F120-I387 HydrophobicContact CE1-CD1 4.12Å; W382-I387 HydrophobicContact CZ3-CD1 3.88Å; W382-I387 HydrophobicContact CZ3-CG1 4Å; T383-I387 HydrophobicContact CG2-CB 4.45Å; T383-I387 HydrophobicContact CG2-CD1 4.24Å; T383-I387 WeakPolarHBondContact O-CB 3.23Å; T383-I387 PolarHBondContact O-N 2.89Å; I387-C389 VanDerWaalsContact C-N 3.33Å; I387-C389 PolarHBondContact O-N 3.21Å; I387-K390 PolarHBondContact O-N 2.88Å; I387-K390 VanDerWaalsContact O-N 3.16Å; I387-Q391 PolarHBondContact O-N 3.37Å
388	D	73.8	Confident	75	Confident	61 Å²	61	69.9 Å²	69.9	33%	0.326	36%	0.364	S	S	.	.	I	π-helix	trans	-64.5	-39.2	-173.2	-58.7	-18.6	0	0	0	111.7	T383 K390 Q391 Q392	T383-D388 PolarHBondContact O-N 3.48Å; D388-K390 VanDerWaalsContact C-N 3.29Å; D388-K390 PolarHBondContact O-N 3Å; D388-Q391 WeakPolarHBondContact O-CB 3.47Å; D388-Q391 PolarHBondContact O-N 2.79Å; D388-Q392 WeakPolarHBondContact O-CG 3.39Å; D388-Q392 PolarHBondContact O-N 2.84Å
389	C	73.3	Confident	74.2	Confident	23 Å²	23	69.3 Å²	69.3	16%	0.155	36%	0.363	C	S	.	.	H	α-helix	trans	-58	-40.2	177	165.9	0	0	0	0	112.8	R384 I387 Q391 Q392 S393 G394 C396	R384-C389 PolarHBondContact O-N 3.38Å; I387-C389 VanDerWaalsContact C-N 3.33Å; I387-C389 PolarHBondContact O-N 3.21Å; C389-Q391 VanDerWaalsContact C-N 3.33Å; C389-Q392 PolarHBondContact O-N 3.3Å; C389-Q392 VanDerWaalsContact O-N 3.16Å; C389-S393 PolarHBondContact O-N 2.97Å; C389-G394 PolarHBondContact O-N 2.79Å; C389-C396 HydrophobicContact CB-CB 3.96Å; C389-C396 WeakPolarHBondContact CB-SG 3.45Å; C389-C396 WeakPolarHBondContact SG-CA 3.44Å; C389-C396 WeakPolarHBondContact SG-CB 3.36Å; C389-C396 PolarHBondContact SG-N 2.92Å; C389-C396 CovalentContact SG-SG 2.05Å; C389-C396 PolarHBondContact SG-SG 2.89Å
390	K	66.1	Low	73.8	Confident	43 Å²	43	75.2 Å²	75.2	19%	0.187	40%	0.399	C	S	.	.	H	α-helix	trans	-74.3	-30.4	-176.6	-66.2	-173.2	177.5	-166.8	0	111.3	P103 D105 T386 I387 D388 Q392 S393 C396	P103-K390 HydrophobicContact CB-CB 3.9Å; P103-K390 HydrophobicContact CB-CD 3.36Å; P103-K390 HydrophobicContact CB-CG 4.25Å; P103-K390 HydrophobicContact CG-CB 3.26Å; P103-K390 HydrophobicContact CG-CD 3.55Å; P103-K390 HydrophobicContact CG-CG 4.06Å; D105-K390 VanDerWaalsContact CG-NZ 3.31Å; D105-K390 IonicContact OD2-NZ 3.38Å; D105-K390 PolarHBondContact OD2-NZ 3.32Å; T386-K390 WeakPolarHBondContact O-CD 3.46Å; T386-K390 VanDerWaalsContact O-CG 3.28Å; T386-K390 WeakPolarHBondContact O-CG 3.28Å; I387-K390 PolarHBondContact O-N 2.88Å; I387-K390 VanDerWaalsContact O-N 3.16Å; D388-K390 VanDerWaalsContact C-N 3.29Å; D388-K390 PolarHBondContact O-N 3Å; K390-Q392 PolarHBondContact O-N 3.03Å; K390-S393 PolarHBondContact O-N 3Å; K390-C396 VanDerWaalsContact CA-SG 3.58Å; K390-C396 HydrophobicContact CG-CB 3.98Å; K390-C396 WeakPolarHBondContact CG-SG 3.48Å; K390-C396 PolarHBondContact N-SG 2.9Å
391	Q	65.9	Low	73.4	Confident	151 Å²	151	78.4 Å²	78.4	71%	0.706	42%	0.421	S	S	*	.	H	α-helix	trans	-65.5	-24.7	171.8	-163.6	172.5	11.3	0	0	112.3	I387 D388 C389	I387-Q391 PolarHBondContact O-N 3.37Å; D388-Q391 WeakPolarHBondContact O-CB 3.47Å; D388-Q391 PolarHBondContact O-N 2.79Å; C389-Q391 VanDerWaalsContact C-N 3.33Å
392	Q	66.3	Low	73.5	Confident	159 Å²	159	74.1 Å²	74.1	74%	0.743	40%	0.401	S	S	*	.	T	Hydrogen-bonded Turn	trans	-94.3	8.8	178.3	-64.7	179.2	4.3	0	0	113.9	D388 C389 K390 G394	D388-Q392 WeakPolarHBondContact O-CG 3.39Å; D388-Q392 PolarHBondContact O-N 2.84Å; C389-Q392 PolarHBondContact O-N 3.3Å; C389-Q392 VanDerWaalsContact O-N 3.16Å; K390-Q392 PolarHBondContact O-N 3.03Å; Q392-G394 PolarHBondContact O-N 2.97Å; Q392-G394 VanDerWaalsContact O-N 3.16Å
393	S	61.4	Low	73.9	Confident	64 Å²	64	78.7 Å²	78.7	45%	0.448	42%	0.423	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.5	24.6	-176.9	-52.2	0	0	0	0	114.2	P99 C389 K390	P99-S393 VanDerWaalsContact CD-OG 3.28Å; P99-S393 WeakPolarHBondContact CD-OG 3.15Å; C389-S393 PolarHBondContact O-N 2.97Å; K390-S393 PolarHBondContact O-N 3Å
394	G	60.5	Low	74.4	Confident	40 Å²	40	77.3 Å²	77.3	41%	0.412	41%	0.414	S	S	.	.			trans	-82.3	162.9	177.2	0	0	0	0	0	113.1	C389 Q392 C396	C389-G394 PolarHBondContact O-N 2.79Å; Q392-G394 PolarHBondContact O-N 2.97Å; Q392-G394 VanDerWaalsContact O-N 3.16Å; G394-C396 PolarHBondContact O-N 3.39Å; G394-C396 VanDerWaalsContact O-N 3.09Å; G394-C396 PolarHBondContact O-SG 3.06Å; G394-C396 VanDerWaalsContact O-SG 3.33Å
395	A	61.8	Low	75	Confident	109 Å²	109	74.2 Å²	74.2	90%	0.901	41%	0.407	S	S	*	.			trans	-73	98.2	169	0	0	0	0	0	109.4	H397	A395-H397 PolarHBondContact O-N 3.04Å
396	C	69.9	Low	75.9	Confident	39 Å²	39	72.4 Å²	72.4	26%	0.264	40%	0.399	S	S	.	.			trans	-80.9	116.6	-174.9	-53.9	0	0	0	0	111.9	C389 K390 G394	C389-C396 HydrophobicContact CB-CB 3.96Å; C389-C396 WeakPolarHBondContact CB-SG 3.45Å; C389-C396 WeakPolarHBondContact SG-CA 3.44Å; C389-C396 WeakPolarHBondContact SG-CB 3.36Å; C389-C396 PolarHBondContact SG-N 2.92Å; C389-C396 CovalentContact SG-SG 2.05Å; C389-C396 PolarHBondContact SG-SG 2.89Å; K390-C396 VanDerWaalsContact CA-SG 3.58Å; K390-C396 HydrophobicContact CG-CB 3.98Å; K390-C396 WeakPolarHBondContact CG-SG 3.48Å; K390-C396 PolarHBondContact N-SG 2.9Å; G394-C396 PolarHBondContact O-N 3.39Å; G394-C396 VanDerWaalsContact O-N 3.09Å; G394-C396 PolarHBondContact O-SG 3.06Å; G394-C396 VanDerWaalsContact O-SG 3.33Å
397	H	72.1	Confident	77	Confident	156 Å²	156	73.2 Å²	73.2	72%	0.722	40%	0.401	S	S	*	.			trans	-88	111.2	170.3	-165.5	73.2	0	0	0	108.5	A395 P399	A395-H397 PolarHBondContact O-N 3.04Å; H397-P399 WeakPolarHBondContact O-CD 3.38Å
398	R	71	Confident	78.1	Confident	120 Å²	120	72.5 Å²	72.5	45%	0.453	40%	0.397	S	S	.	.	P	Polyproline II helix	trans	-66.2	120.3	172.6	-74.1	-168.9	-173.6	-177.1	3.8	107.9	D105 T386	D105-R398 IonicContact OD2-CZ 2.88Å; D105-R398 IonicContact OD2-NH2 2.92Å; D105-R398 PolarHBondContact OD2-NH2 2.94Å; T386-R398 HydrophobicContact CG2-CB 4.47Å; T386-R398 HydrophobicContact CG2-CG 4.09Å
399	P	77.1	Confident	79.2	Confident	20 Å²	20	72.7 Å²	72.7	13%	0.13	40%	0.401	C	S	.	.	P	Polyproline II helix	trans	-64.5	163.9	173.9	28.1	-31.6	0	0	0	109.5	W382 M385 T386 H397	W382-P399 HydrophobicContact CB-CG 4.46Å; W382-P399 HydrophobicContact CG-CG 4.26Å; M385-P399 HydrophobicContact CB-CG 4.24Å; M385-P399 HydrophobicContact SD-CB 4.09Å; M385-P399 HydrophobicContact SD-CG 4.22Å; T386-P399 HydrophobicContact CG2-CG 4.44Å; H397-P399 WeakPolarHBondContact O-CD 3.38Å
400	T	81	Confident	80.2	Confident	125 Å²	125	71.9 Å²	71.9	77%	0.767	40%	0.396	S	S	*	.	P	Polyproline II helix	trans	-50.8	134.7	175.4	47.6	0	0	0	0	110.5
401	P	82.6	Confident	81.7	Confident	100 Å²	100	70.6 Å²	70.6	65%	0.649	39%	0.392	S	S	*	.	P	Polyproline II helix	trans	-59.4	146.9	-178.1	24.6	-33.4	0	0	0	110.8
402	P	90.2	Very high	83.2	Confident	6 Å²	6	65 Å²	65	4%	0.039	37%	0.366	C	S	.	.	P	Polyproline II helix	trans	-60.8	140.4	178.1	24	-33.4	0	0	0	112	M127 F128 I378 A404 Y407	M127-P402 HydrophobicContact CB-CG 4.01Å; M127-P402 WeakPolarHBondContact O-CD 3.4Å; M127-P402 WeakPolarHBondContact O-CG 3.38Å; F128-P402 HydrophobicContact CD1-CG 4.21Å; F128-P402 HydrophobicContact CE1-CB 4.02Å; F128-P402 HydrophobicContact CE1-CG 3.58Å; F128-P402 HydrophobicContact CE2-CG 4.4Å; F128-P402 HydrophobicContact CZ-CB 4.2Å; F128-P402 HydrophobicContact CZ-CG 3.69Å; I378-P402 HydrophobicContact CG2-CB 3.97Å; P402-A404 PolarHBondContact O-N 3.37Å; P402-A404 VanDerWaalsContact O-N 3.14Å; P402-Y407 HydrophobicContact CB-CE2 3.93Å
403	Q	92.5	Very high	84.6	Confident	111 Å²	111	57.9 Å²	57.9	52%	0.519	33%	0.334	S	S	.	.			trans	-63.8	110.1	170.4	-66.5	179.6	-22.5	0	0	110.3	E405 I406 Y407	Q403-E405 PolarHBondContact O-N 3.04Å; Q403-I406 HydrophobicContact CB-CD1 4.2Å; Q403-I406 HydrophobicContact CB-CG1 4.28Å; Q403-I406 PolarHBondContact O-N 3.08Å; Q403-Y407 WeakPolarHBondContact O-CD2 3.37Å
404	A	93.2	Very high	86.3	Confident	1 Å²	1	55.8 Å²	55.8	1%	0.008	32%	0.319	C	S	.	.	H	α-helix	trans	-67.5	-27.1	-176.8	0	0	0	0	0	112.4	F128 N132 P402 I406 Y407 M408	F128-A404 HydrophobicContact CD1-CB 3.88Å; F128-A404 HydrophobicContact CE1-CB 4.09Å; N132-A404 HydrophobicContact CB-CB 3.73Å; P402-A404 PolarHBondContact O-N 3.37Å; P402-A404 VanDerWaalsContact O-N 3.14Å; A404-I406 VanDerWaalsContact C-N 3.32Å; A404-I406 PolarHBondContact O-N 3.1Å; A404-Y407 PolarHBondContact O-N 2.99Å; A404-M408 WeakPolarHBondContact O-CB 3.33Å; A404-M408 PolarHBondContact O-N 3.37Å
405	E	93.6	Very high	88	Confident	105 Å²	105	54 Å²	54	49%	0.491	30%	0.301	S	S	.	.	H	α-helix	trans	-60.9	-41.1	179.6	-57.8	77.6	-169.8	0	0	110.9	Q403 M408 T409	Q403-E405 PolarHBondContact O-N 3.04Å; E405-M408 WeakPolarHBondContact O-CB 3.34Å; E405-M408 PolarHBondContact O-N 3.28Å; E405-T409 PolarHBondContact O-N 2.85Å; E405-T409 PolarHBondContact O-OG1 2.74Å
406	I	95.8	Very high	89.6	Confident	42 Å²	42	50 Å²	50	22%	0.215	27%	0.267	C	S	.	.	H	α-helix	trans	-67.8	-40.1	178.6	-60.6	178.3	0	0	0	110.9	C371 Y374 Q403 A404 M408 T409 A410	C371-I406 HydrophobicContact CB-CG2 4.1Å; Y374-I406 HydrophobicContact CD1-CB 4.05Å; Y374-I406 HydrophobicContact CD1-CD1 4.07Å; Y374-I406 HydrophobicContact CD1-CG2 3.47Å; Y374-I406 VanDerWaalsContact CD1-CG2 3.47Å; Y374-I406 HydrophobicContact CD2-CD1 4.21Å; Y374-I406 HydrophobicContact CE1-CB 3.96Å; Y374-I406 HydrophobicContact CE1-CD1 3.74Å; Y374-I406 HydrophobicContact CE1-CG1 4.41Å; Y374-I406 HydrophobicContact CE1-CG2 3.94Å; Y374-I406 HydrophobicContact CE2-CD1 3.92Å; Y374-I406 HydrophobicContact CG-CD1 4.27Å; Y374-I406 HydrophobicContact CG-CG2 4.02Å; Q403-I406 HydrophobicContact CB-CD1 4.2Å; Q403-I406 HydrophobicContact CB-CG1 4.28Å; Q403-I406 PolarHBondContact O-N 3.08Å; A404-I406 VanDerWaalsContact C-N 3.32Å; A404-I406 PolarHBondContact O-N 3.1Å; I406-M408 VanDerWaalsContact C-N 3.31Å; I406-T409 PolarHBondContact O-N 2.95Å; I406-A410 PolarHBondContact O-N 3.46Å
407	Y	95.3	Very high	90.6	Very high	23 Å²	23	48.8 Å²	48.8	9%	0.09	26%	0.258	C	S	.	.	H	α-helix	trans	-65.7	-38.4	175.3	-77.4	-114.5	0	0	0	111.1	F128 L290 Y374 K375 P402 Q403 A404 A410 V411	F128-Y407 HydrophobicContact CE1-CD2 4.35Å; F128-Y407 HydrophobicContact CE1-CG 4.43Å; F128-Y407 AromaticContact CZ-CD1 3.89Å; F128-Y407 HydrophobicContact CZ-CD1 3.89Å; F128-Y407 HydrophobicContact CZ-CD2 4.13Å; F128-Y407 AromaticContact CZ-CE1 3.91Å; F128-Y407 HydrophobicContact CZ-CE1 3.91Å; F128-Y407 HydrophobicContact CZ-CE2 4.17Å; F128-Y407 AromaticContact CZ-CG 4Å; F128-Y407 HydrophobicContact CZ-CG 4Å; L290-Y407 HydrophobicContact CD2-CD1 4.39Å; L290-Y407 HydrophobicContact CD2-CG 4.26Å; Y374-Y407 HydrophobicContact CD1-CE2 4.3Å; Y374-Y407 HydrophobicContact CE1-CD2 4.38Å; Y374-Y407 AromaticContact CE1-CE2 3.93Å; Y374-Y407 HydrophobicContact CE1-CE2 3.93Å; K375-Y407 HydrophobicContact CB-CE1 4.23Å; K375-Y407 HydrophobicContact CD-CD1 4.45Å; K375-Y407 HydrophobicContact CD-CE1 3.87Å; K375-Y407 HydrophobicContact CG-CE1 3.61Å; P402-Y407 HydrophobicContact CB-CE2 3.93Å; Q403-Y407 WeakPolarHBondContact O-CD2 3.37Å; A404-Y407 PolarHBondContact O-N 2.99Å; Y407-A410 WeakPolarHBondContact O-CB 3.39Å; Y407-A410 PolarHBondContact O-N 3.18Å; Y407-V411 PolarHBondContact O-N 2.02Å; Y407-V411 VanDerWaalsContact O-N 3.15Å
408	M	95.7	Very high	91.5	Very high	24 Å²	24	41.3 Å²	41.3	12%	0.118	22%	0.224	C	C	.	.	H	α-helix	trans	-63.4	-43	173.6	-172.5	174.2	151.2	0	0	111.7	M135 V136 W139 A404 E405 I406 A410 V411 I412	M135-M408 HydrophobicContact CE-SD 4.07Å; M135-M408 HydrophobicContact CG-SD 4.2Å; M135-M408 HydrophobicContact SD-SD 4.5Å; V136-M408 HydrophobicContact CG2-CB 3.77Å; V136-M408 HydrophobicContact CG2-CG 3.97Å; V136-M408 HydrophobicContact CG2-SD 4.01Å; W139-M408 HydrophobicContact CB-CE 3.48Å; W139-M408 VanDerWaalsContact CB-CE 3.48Å; W139-M408 HydrophobicContact CB-SD 4.49Å; W139-M408 HydrophobicContact CD2-CE 3.89Å; W139-M408 HydrophobicContact CG-CE 3.28Å; A404-M408 WeakPolarHBondContact O-CB 3.33Å; A404-M408 PolarHBondContact O-N 3.37Å; E405-M408 WeakPolarHBondContact O-CB 3.34Å; E405-M408 PolarHBondContact O-N 3.28Å; I406-M408 VanDerWaalsContact C-N 3.31Å; M408-A410 VanDerWaalsContact C-N 3.28Å; M408-A410 PolarHBondContact O-N 3.13Å; M408-V411 PolarHBondContact O-N 3.33Å; M408-V411 VanDerWaalsContact O-N 3.16Å; M408-I412 HydrophobicContact CE-CD1 3.53Å; M408-I412 HydrophobicContact CG-CD1 3.82Å; M408-I412 HydrophobicContact CG-CG1 4.39Å; M408-I412 WeakPolarHBondContact O-CG1 3.42Å; M408-I412 PolarHBondContact O-N 3.39Å
409	T	96.9	Very high	92.5	Very high	65 Å²	65	39 Å²	39	40%	0.399	22%	0.217	S	C	.	.	H	α-helix	trans	-58.5	-41	173.9	-57.2	0	0	0	0	111.2	I367 E405 I406 V411 I412 S413	I367-T409 HydrophobicContact CG2-CG2 3.79Å; E405-T409 PolarHBondContact O-N 2.85Å; E405-T409 PolarHBondContact O-OG1 2.74Å; I406-T409 PolarHBondContact O-N 2.95Å; T409-V411 PolarHBondContact O-N 3.03Å; T409-I412 PolarHBondContact O-N 3.15Å; T409-S413 WeakPolarHBondContact O-CB 3.18Å; T409-S413 PolarHBondContact O-N 3Å; T409-S413 PolarHBondContact O-OG 3Å
410	A	96.3	Very high	93.3	Very high	7 Å²	7	38 Å²	38	6%	0.058	21%	0.211	C	C	.	.	H	α-helix	trans	-57.5	-49.4	174.3	0	0	0	0	0	111.3	C371 I406 Y407 M408 S413 S414	C371-A410 HydrophobicContact CB-CB 3.57Å; I406-A410 PolarHBondContact O-N 3.46Å; Y407-A410 WeakPolarHBondContact O-CB 3.39Å; Y407-A410 PolarHBondContact O-N 3.18Å; M408-A410 VanDerWaalsContact C-N 3.28Å; M408-A410 PolarHBondContact O-N 3.13Å; A410-S413 PolarHBondContact O-N 2.96Å; A410-S413 PolarHBondContact O-OG 3.49Å; A410-S414 PolarHBondContact O-N 3.5Å
411	V	96.3	Very high	93.7	Very high	15 Å²	15	32 Å²	32	9%	0.091	17%	0.174	C	C	.	.	H	α-helix	trans	-62	-49.8	178.9	175.7	0	0	0	0	111.4	S140 Y186 T291 Y407 M408 T409 S413 S414 L415	S140-V411 WeakPolarHBondContact OG-CG1 3.47Å; Y186-V411 HydrophobicContact CD1-CG1 4.08Å; Y186-V411 HydrophobicContact CE1-CG1 3.53Å; Y186-V411 HydrophobicContact CE1-CG2 4.47Å; T291-V411 HydrophobicContact CG2-CG2 4.04Å; Y407-V411 PolarHBondContact O-N 2.02Å; Y407-V411 VanDerWaalsContact O-N 3.15Å; M408-V411 PolarHBondContact O-N 3.33Å; M408-V411 VanDerWaalsContact O-N 3.16Å; T409-V411 PolarHBondContact O-N 3.03Å; V411-S413 VanDerWaalsContact C-N 3.34Å; V411-S413 PolarHBondContact O-N 2.87Å; V411-S414 PolarHBondContact O-N 3.29Å; V411-S414 PolarHBondContact O-OG 3.21Å; V411-L415 HydrophobicContact CG1-CD1 3.93Å; V411-L415 WeakPolarHBondContact O-CG 3.38Å; V411-L415 PolarHBondContact O-N 2.97Å; V411-L415 VanDerWaalsContact O-N 3.08Å
412	I	96.7	Very high	93.9	Very high	35 Å²	35	29.4 Å²	29.4	18%	0.179	15%	0.154	C	C	.	.	H	α-helix	trans	-62.4	-42.5	-179.2	-69.4	173.3	0	0	0	111.2	F143 M408 T409 S414 L415 A416	F143-I412 HydrophobicContact CD1-CG2 3.88Å; F143-I412 HydrophobicContact CD2-CD1 3.93Å; F143-I412 HydrophobicContact CD2-CG1 3.76Å; F143-I412 HydrophobicContact CD2-CG2 4.19Å; F143-I412 HydrophobicContact CE1-CG2 3.73Å; F143-I412 HydrophobicContact CE2-CD1 3.65Å; F143-I412 HydrophobicContact CE2-CG1 3.96Å; F143-I412 HydrophobicContact CE2-CG2 4.05Å; F143-I412 HydrophobicContact CG-CG1 4.22Å; F143-I412 HydrophobicContact CG-CG2 4.11Å; F143-I412 HydrophobicContact CZ-CD1 4.3Å; F143-I412 HydrophobicContact CZ-CG2 3.82Å; M408-I412 HydrophobicContact CE-CD1 3.53Å; M408-I412 HydrophobicContact CG-CD1 3.82Å; M408-I412 HydrophobicContact CG-CG1 4.39Å; M408-I412 WeakPolarHBondContact O-CG1 3.42Å; M408-I412 PolarHBondContact O-N 3.39Å; T409-I412 PolarHBondContact O-N 3.15Å; I412-S414 VanDerWaalsContact C-N 3.32Å; I412-S414 PolarHBondContact O-N 3.3Å; I412-L415 CarbonylContact O-C 3.55Å; I412-L415 PolarHBondContact O-N 2.97Å; I412-L415 VanDerWaalsContact O-N 3.13Å; I412-A416 WeakPolarHBondContact O-CB 3.38Å; I412-A416 PolarHBondContact O-N 3.49Å
413	S	97	Very high	93.7	Very high	8 Å²	8	32 Å²	32	6%	0.056	17%	0.167	C	C	.	.	H	α-helix	trans	-62.8	-38.9	178.3	67.6	0	0	0	0	111.8	P364 E368 T409 A410 V411 L415 A416	P364-S413 VanDerWaalsContact CB-O 3.22Å; P364-S413 WeakPolarHBondContact CB-O 3.44Å; P364-S413 WeakPolarHBondContact O-CB 3.42Å; E368-S413 WeakPolarHBondContact CA-OG 3.03Å; E368-S413 VanDerWaalsContact CB-OG 3.27Å; E368-S413 WeakPolarHBondContact CB-OG 3.05Å; E368-S413 PolarHBondContact N-OG 2.84Å; T409-S413 WeakPolarHBondContact O-CB 3.18Å; T409-S413 PolarHBondContact O-N 3Å; T409-S413 PolarHBondContact O-OG 3Å; A410-S413 PolarHBondContact O-N 2.96Å; A410-S413 PolarHBondContact O-OG 3.49Å; V411-S413 VanDerWaalsContact C-N 3.34Å; V411-S413 PolarHBondContact O-N 2.87Å; S413-L415 VanDerWaalsContact C-N 3.32Å; S413-L415 PolarHBondContact O-N 3.45Å; S413-A416 PolarHBondContact O-N 3.47Å; S413-A416 VanDerWaalsContact O-N 3.17Å
414	S	95.8	Very high	93.1	Very high	21 Å²	21	26.8 Å²	26.8	15%	0.147	14%	0.143	C	C	.	.	H	α-helix	trans	-61.6	-40.5	172.5	81.4	0	0	0	0	112.1	E368 A410 V411 I412 A416 T417	E368-S414 VanDerWaalsContact CD-CB 3.45Å; E368-S414 WeakPolarHBondContact OE2-CA 3.02Å; E368-S414 VanDerWaalsContact OE2-CB 3.29Å; E368-S414 WeakPolarHBondContact OE2-CB 3.35Å; A410-S414 PolarHBondContact O-N 3.5Å; V411-S414 PolarHBondContact O-N 3.29Å; V411-S414 PolarHBondContact O-OG 3.21Å; I412-S414 VanDerWaalsContact C-N 3.32Å; I412-S414 PolarHBondContact O-N 3.3Å; S414-A416 VanDerWaalsContact C-N 3.3Å; S414-A416 PolarHBondContact O-N 3.22Å; S414-T417 WeakPolarHBondContact O-CG2 3.47Å; S414-T417 PolarHBondContact O-OG1 3.34Å
415	L	96.6	Very high	92.6	Very high	3 Å²	3	26.9 Å²	26.9	2%	0.016	14%	0.143	C	C	.	.	H	α-helix	trans	-79.5	-5.5	177.5	-63.2	172.3	0	0	0	113.5	F143 A144 N147 Y186 V411 I412 S413	F143-L415 HydrophobicContact CB-CB 4.1Å; F143-L415 HydrophobicContact CB-CD1 3.98Å; A144-L415 HydrophobicContact CB-CD1 4.01Å; A144-L415 HydrophobicContact CB-CD2 4.08Å; N147-L415 HydrophobicContact CB-CB 4.47Å; N147-L415 WeakPolarHBondContact CB-O 3.33Å; N147-L415 PolarHBondContact OD1-O 3.28Å; Y186-L415 HydrophobicContact CD2-CD1 4.48Å; Y186-L415 HydrophobicContact CD2-CD2 3.85Å; Y186-L415 HydrophobicContact CE2-CD2 4.13Å; Y186-L415 HydrophobicContact CG-CD1 4.33Å; Y186-L415 HydrophobicContact CG-CD2 4.44Å; V411-L415 HydrophobicContact CG1-CD1 3.93Å; V411-L415 WeakPolarHBondContact O-CG 3.38Å; V411-L415 PolarHBondContact O-N 2.97Å; V411-L415 VanDerWaalsContact O-N 3.08Å; I412-L415 CarbonylContact O-C 3.55Å; I412-L415 PolarHBondContact O-N 2.97Å; I412-L415 VanDerWaalsContact O-N 3.13Å; S413-L415 VanDerWaalsContact C-N 3.32Å; S413-L415 PolarHBondContact O-N 3.45Å
416	A	95.1	Very high	92.1	Very high	25 Å²	25	27.7 Å²	27.7	21%	0.207	15%	0.15	C	C	.	.	H	α-helix	trans	-86.8	-14.5	175	0	0	0	0	0	112.4	P364 I412 S413 S414 G418 F419	P364-A416 HydrophobicContact CB-CB 4.12Å; P364-A416 HydrophobicContact CG-CB 4.14Å; I412-A416 WeakPolarHBondContact O-CB 3.38Å; I412-A416 PolarHBondContact O-N 3.49Å; S413-A416 PolarHBondContact O-N 3.47Å; S413-A416 VanDerWaalsContact O-N 3.17Å; S414-A416 VanDerWaalsContact C-N 3.3Å; S414-A416 PolarHBondContact O-N 3.22Å; A416-G418 VanDerWaalsContact C-N 3.3Å; A416-G418 PolarHBondContact O-N 3.28Å; A416-F419 HydrophobicContact CB-CD2 4.42Å; A416-F419 WeakPolarHBondContact O-CD2 3.25Å; A416-F419 PolarHBondContact O-N 2.95Å
417	T	92.6	Very high	91.4	Very high	12 Å²	12	28 Å²	28	7%	0.074	16%	0.156	C	C	.	.	G	3₁₀ helix	trans	-62.7	-31.2	-173.3	55.5	0	0	0	0	113.8	P364 N365 S414 F419 S420	P364-T417 HydrophobicContact CB-CG2 4.26Å; N365-T417 VanDerWaalsContact ND2-CG2 3.3Å; N365-T417 WeakPolarHBondContact ND2-CG2 3.17Å; S414-T417 WeakPolarHBondContact O-CG2 3.47Å; S414-T417 PolarHBondContact O-OG1 3.34Å; T417-F419 VanDerWaalsContact C-N 3.31Å; T417-F419 PolarHBondContact O-N 3.34Å; T417-S420 WeakPolarHBondContact O-CB 3.25Å; T417-S420 PolarHBondContact O-N 3.42Å; T417-S420 PolarHBondContact O-OG 3.14Å
418	G	90.5	Very high	90.6	Very high	0 Å²	0	30.1 Å²	30.1	0%	0	18%	0.178	C	C	.	.	G	3₁₀ helix	trans	-71.4	-21	179.4	0	0	0	0	0	114.3	N147 V150 A416 S420 C421	N147-G418 WeakPolarHBondContact OD1-CA 3.49Å; N147-G418 PolarHBondContact OD1-N 3Å; V150-G418 WeakPolarHBondContact CG1-O 3.47Å; A416-G418 VanDerWaalsContact C-N 3.3Å; A416-G418 PolarHBondContact O-N 3.28Å; G418-S420 PolarHBondContact O-N 2.97Å; G418-C421 VanDerWaalsContact O-CB 3.28Å; G418-C421 WeakPolarHBondContact O-CB 3.38Å; G418-C421 PolarHBondContact O-N 3.09Å
419	F	91.8	Very high	89.9	Confident	70 Å²	70	35.3 Å²	35.3	31%	0.307	20%	0.2	S	C	.	.	G	3₁₀ helix	trans	-60.9	-26	173.2	-69.2	-73.3	0	0	0	112.3	A146 V150 A416 T417 C421 L422	A146-F419 HydrophobicContact CB-CZ 3.94Å; V150-F419 HydrophobicContact CG2-CD1 4.18Å; V150-F419 HydrophobicContact CG2-CE1 4.1Å; A416-F419 HydrophobicContact CB-CD2 4.42Å; A416-F419 WeakPolarHBondContact O-CD2 3.25Å; A416-F419 PolarHBondContact O-N 2.95Å; T417-F419 VanDerWaalsContact C-N 3.31Å; T417-F419 PolarHBondContact O-N 3.34Å; F419-C421 PolarHBondContact O-N 3.23Å; F419-L422 HydrophobicContact CD1-CD1 3.96Å; F419-L422 WeakPolarHBondContact O-CB 3.3Å; F419-L422 PolarHBondContact O-N 2.72Å
420	S	93.1	Very high	89.1	Confident	0 Å²	0	32.4 Å²	32.4	0%	0	18%	0.182	C	C	.	.	G	3₁₀ helix	trans	-57.8	-32.9	172	70.6	0	0	0	0	112.3	F357 T417 G418 L422	F357-S420 WeakPolarHBondContact CD2-O 3.29Å; T417-S420 WeakPolarHBondContact O-CB 3.25Å; T417-S420 PolarHBondContact O-N 3.42Å; T417-S420 PolarHBondContact O-OG 3.14Å; G418-S420 PolarHBondContact O-N 2.97Å; S420-L422 VanDerWaalsContact C-N 3.31Å; S420-L422 PolarHBondContact O-N 3.21Å
421	C	90.1	Very high	88.4	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	21%	0.208	C	C	.	.	G	3₁₀ helix	trans	-68.7	-25.3	-178.8	-61.4	0	0	0	0	113.5	S154 G418 F419 M423 W424	S154-C421 WeakPolarHBondContact OG-CB 3.44Å; G418-C421 VanDerWaalsContact O-CB 3.28Å; G418-C421 WeakPolarHBondContact O-CB 3.38Å; G418-C421 PolarHBondContact O-N 3.09Å; F419-C421 PolarHBondContact O-N 3.23Å; C421-M423 PolarHBondContact O-N 3.39Å; C421-M423 VanDerWaalsContact O-N 3.11Å; C421-W424 WeakPolarHBondContact O-CB 3.4Å; C421-W424 PolarHBondContact O-N 3.28Å
422	L	86.8	Confident	87.7	Confident	44 Å²	44	41.7 Å²	41.7	23%	0.23	23%	0.23	C	C	.	.	H	α-helix	trans	-54.5	-35.4	179.5	-76.9	175	0	0	0	112.6	V150 F419 S420 W424 V425 L426	V150-L422 HydrophobicContact CB-CD2 4.36Å; V150-L422 HydrophobicContact CB-CG 4.46Å; V150-L422 HydrophobicContact CG1-CD1 4.2Å; V150-L422 HydrophobicContact CG1-CD2 3.68Å; V150-L422 HydrophobicContact CG1-CG 3.49Å; V150-L422 VanDerWaalsContact CG1-CG 3.49Å; V150-L422 HydrophobicContact CG2-CD1 4.11Å; V150-L422 HydrophobicContact CG2-CD2 4.01Å; V150-L422 HydrophobicContact CG2-CG 4.16Å; F419-L422 HydrophobicContact CD1-CD1 3.96Å; F419-L422 WeakPolarHBondContact O-CB 3.3Å; F419-L422 PolarHBondContact O-N 2.72Å; S420-L422 VanDerWaalsContact C-N 3.31Å; S420-L422 PolarHBondContact O-N 3.21Å; L422-W424 PolarHBondContact O-N 2.98Å; L422-V425 HydrophobicContact CD2-CG2 4.47Å; L422-V425 WeakPolarHBondContact O-CG2 3.06Å; L422-V425 PolarHBondContact O-N 2.05Å; L422-L426 HydrophobicContact CB-CD1 3.95Å; L422-L426 HydrophobicContact CB-CG 4.27Å; L422-L426 HydrophobicContact CD2-CG 4.5Å; L422-L426 WeakPolarHBondContact O-CB 3.48Å; L422-L426 VanDerWaalsContact O-CG 3.3Å; L422-L426 WeakPolarHBondContact O-CG 3.27Å; L422-L426 PolarHBondContact O-N 3.44Å
423	M	85.1	Confident	86.9	Confident	61 Å²	61	41.1 Å²	41.1	30%	0.3	23%	0.23	S	C	.	.	H	α-helix	trans	-60.2	-22.9	-179.1	-68.3	-60.4	-53.6	0	0	113.9	K353 F356 L360 C421	K353-M423 WeakPolarHBondContact CE-O 3.23Å; F356-M423 HydrophobicContact CD1-CE 3.6Å; F356-M423 HydrophobicContact CD1-CG 3.48Å; F356-M423 VanDerWaalsContact CD1-CG 3.48Å; F356-M423 HydrophobicContact CD1-SD 3.4Å; F356-M423 WeakPolarHBondContact CD1-SD 3.27Å; F356-M423 HydrophobicContact CE1-CE 4.07Å; F356-M423 HydrophobicContact CE1-CG 3.65Å; F356-M423 HydrophobicContact CE1-SD 3.31Å; F356-M423 WeakPolarHBondContact CE1-SD 3.37Å; F356-M423 HydrophobicContact CG-CE 4.49Å; L360-M423 HydrophobicContact CD1-CG 4.33Å; C421-M423 PolarHBondContact O-N 3.39Å; C421-M423 VanDerWaalsContact O-N 3.11Å
424	W	81.2	Confident	86.4	Confident	2 Å²	2	43.2 Å²	43.2	1%	0.008	24%	0.237	C	C	.	.	H	α-helix	trans	-83.8	-25	179.2	-67.5	93.3	0	0	0	113.2	F158 E169 V172 K353 M354 F357 C421 L422	F158-W424 HydrophobicContact CE2-CB 4.01Å; F158-W424 HydrophobicContact CZ-CB 3.56Å; F158-W424 HydrophobicContact CZ-CD2 4.48Å; F158-W424 HydrophobicContact CZ-CG 4.01Å; E169-W424 HydrophobicContact CB-CE3 4.48Å; E169-W424 HydrophobicContact CB-CZ3 4.19Å; E169-W424 VanDerWaalsContact CD-CZ3 3.49Å; E169-W424 HydrophobicContact CG-CE3 4.32Å; E169-W424 HydrophobicContact CG-CH2 4.02Å; E169-W424 HydrophobicContact CG-CZ3 3.58Å; E169-W424 WeakPolarHBondContact OE1-CZ3 3.24Å; V172-W424 HydrophobicContact CG1-CG 4.07Å; K353-W424 HydrophobicContact CD-CE3 4.36Å; K353-W424 HydrophobicContact CD-CH2 3.96Å; K353-W424 HydrophobicContact CD-CZ3 3.9Å; K353-W424 HydrophobicContact CG-CH2 4.24Å; K353-W424 HydrophobicContact CG-CZ2 4.43Å; M354-W424 HydrophobicContact CE-CH2 3.37Å; M354-W424 HydrophobicContact CE-CZ2 4.08Å; M354-W424 HydrophobicContact CE-CZ3 4.25Å; M354-W424 HydrophobicContact CG-CH2 4.37Å; M354-W424 HydrophobicContact SD-CH2 3.35Å; M354-W424 WeakPolarHBondContact SD-CH2 3.5Å; M354-W424 HydrophobicContact SD-CZ2 3.46Å; M354-W424 WeakPolarHBondContact SD-CZ2 3.17Å; F357-W424 HydrophobicContact CB-CZ2 4.46Å; F357-W424 AromaticContact CD2-CD1 3.83Å; F357-W424 AromaticContact CD2-NE1 3.21Å; F357-W424 AromaticContact CE2-NE1 3.72Å; F357-W424 HydrophobicContact CG-CZ2 4.45Å; F357-W424 AromaticContact CG-NE1 3.42Å; C421-W424 WeakPolarHBondContact O-CB 3.4Å; C421-W424 PolarHBondContact O-N 3.28Å; L422-W424 PolarHBondContact O-N 2.98Å
425	V	82.9	Confident	85.8	Confident	2 Å²	2	48.1 Å²	48.1	1%	0.012	26%	0.256	C	S	.	.	H	α-helix	trans	-114.9	-16.7	-169.1	-61.5	0	0	0	0	113.5	F153 T157 F158 L422 S427 T430	F153-V425 HydrophobicContact CD1-CB 4.39Å; F153-V425 HydrophobicContact CD1-CG2 3.79Å; F153-V425 HydrophobicContact CE1-CB 3.98Å; F153-V425 HydrophobicContact CE1-CG2 3.71Å; T157-V425 HydrophobicContact CG2-CB 4.06Å; T157-V425 HydrophobicContact CG2-CG1 3.63Å; F158-V425 HydrophobicContact CE2-CG1 4.33Å; L422-V425 HydrophobicContact CD2-CG2 4.47Å; L422-V425 WeakPolarHBondContact O-CG2 3.06Å; L422-V425 PolarHBondContact O-N 2.05Å; V425-S427 VanDerWaalsContact C-N 3.33Å; V425-S427 PolarHBondContact O-N 2.79Å; V425-T430 WeakPolarHBondContact O-CB 3.11Å; V425-T430 WeakPolarHBondContact O-CG2 3.42Å; V425-T430 PolarHBondContact O-OG1 3.24Å
426	L	82.1	Confident	85	Confident	123 Å²	123	52.7 Å²	52.7	64%	0.644	28%	0.28	S	S	*	.			trans	-76.1	81.5	171	-65.5	178	0	0	0	110.9	L422	L422-L426 HydrophobicContact CB-CD1 3.95Å; L422-L426 HydrophobicContact CB-CG 4.27Å; L422-L426 HydrophobicContact CD2-CG 4.5Å; L422-L426 WeakPolarHBondContact O-CB 3.48Å; L422-L426 VanDerWaalsContact O-CG 3.3Å; L422-L426 WeakPolarHBondContact O-CG 3.27Å; L422-L426 PolarHBondContact O-N 3.44Å
427	S	81	Confident	84.4	Confident	48 Å²	48	57 Å²	57	34%	0.336	29%	0.294	S	S	.	.	S	Bend	trans	-146.5	148.8	176.4	-177.6	0	0	0	0	111	V425 K429 T430 V431	V425-S427 VanDerWaalsContact C-N 3.33Å; V425-S427 PolarHBondContact O-N 2.79Å; S427-K429 PolarHBondContact O-N 3.43Å; S427-K429 VanDerWaalsContact O-N 3.12Å; S427-K429 PolarHBondContact OG-N 3.34Å; S427-T430 WeakPolarHBondContact O-CA 3.01Å; S427-T430 VanDerWaalsContact O-CB 3.24Å; S427-T430 WeakPolarHBondContact O-CB 3.02Å; S427-T430 PolarHBondContact O-N 3.49Å; S427-V431 PolarHBondContact O-N 3.34Å
428	A	79.3	Confident	84	Confident	68 Å²	68	61.4 Å²	61.4	56%	0.562	32%	0.316	S	S	*	.	H	α-helix	trans	-52	-35.3	170.6	0	0	0	0	0	111.8	T430 V431 H432	A428-T430 VanDerWaalsContact C-N 3.27Å; A428-T430 PolarHBondContact O-N 3Å; A428-V431 WeakPolarHBondContact O-CB 3.33Å; A428-V431 PolarHBondContact O-N 3.46Å; A428-H432 PolarHBondContact O-N 3.03Å; A428-H432 VanDerWaalsContact O-N 3.11Å; A428-H432 PolarHBondContact O-ND1 3.4Å
429	K	80.3	Confident	83.3	Confident	132 Å²	132	68.9 Å²	68.9	57%	0.574	35%	0.349	S	S	*	.	H	α-helix	trans	-63.4	-32.6	176.9	-64.4	-178.8	174.6	-177.2	0	112.9	R164 S427 H432 A433	R164-K429 VanDerWaalsContact NH1-CB 3.28Å; R164-K429 VanDerWaalsContact NH2-CD 3.32Å; S427-K429 PolarHBondContact O-N 3.43Å; S427-K429 VanDerWaalsContact O-N 3.12Å; S427-K429 PolarHBondContact OG-N 3.34Å; K429-H432 PolarHBondContact O-N 2.02Å; K429-A433 WeakPolarHBondContact O-CB 3.46Å; K429-A433 PolarHBondContact O-N 3.48Å
430	T	81	Confident	82	Confident	5 Å²	5	69.3 Å²	69.3	3%	0.031	36%	0.36	C	S	.	.	H	α-helix	trans	-66.6	-45.2	175.2	-53.7	0	0	0	0	110.3	F153 T157 V425 S427 A428 H432 A433 W434	F153-T430 HydrophobicContact CZ-CG2 4.05Å; T157-T430 HydrophobicContact CG2-CG2 3.55Å; V425-T430 WeakPolarHBondContact O-CB 3.11Å; V425-T430 WeakPolarHBondContact O-CG2 3.42Å; V425-T430 PolarHBondContact O-OG1 3.24Å; S427-T430 WeakPolarHBondContact O-CA 3.01Å; S427-T430 VanDerWaalsContact O-CB 3.24Å; S427-T430 WeakPolarHBondContact O-CB 3.02Å; S427-T430 PolarHBondContact O-N 3.49Å; A428-T430 VanDerWaalsContact C-N 3.27Å; A428-T430 PolarHBondContact O-N 3Å; T430-H432 VanDerWaalsContact C-N 3.27Å; T430-H432 PolarHBondContact O-N 3.19Å; T430-A433 PolarHBondContact O-N 3.01Å; T430-A433 VanDerWaalsContact O-N 3.15Å; T430-W434 VanDerWaalsContact CG2-CD1 3.48Å; T430-W434 VanDerWaalsContact O-CD1 3.26Å; T430-W434 PolarHBondContact O-N 3.1Å
431	V	82.3	Confident	80.1	Confident	99 Å²	99	72 Å²	72	60%	0.6	39%	0.387	S	S	*	.	H	α-helix	trans	-57.8	-41.7	175.8	-179	0	0	0	0	111.1	S427 A428 K435	S427-V431 PolarHBondContact O-N 3.34Å; A428-V431 WeakPolarHBondContact O-CB 3.33Å; A428-V431 PolarHBondContact O-N 3.46Å; V431-K435 VanDerWaalsContact O-CB 3.22Å; V431-K435 WeakPolarHBondContact O-CB 3.23Å; V431-K435 PolarHBondContact O-N 3.16Å
432	H	81.3	Confident	78.4	Confident	118 Å²	118	80.7 Å²	80.7	55%	0.546	43%	0.43	S	S	.	.	H	α-helix	trans	-66.4	-42.9	176.3	-70.5	75.8	0	0	0	112.5	A428 K429 T430 K435 N436	A428-H432 PolarHBondContact O-N 3.03Å; A428-H432 VanDerWaalsContact O-N 3.11Å; A428-H432 PolarHBondContact O-ND1 3.4Å; K429-H432 PolarHBondContact O-N 2.02Å; T430-H432 VanDerWaalsContact C-N 3.27Å; T430-H432 PolarHBondContact O-N 3.19Å; H432-K435 PolarHBondContact O-N 3.42Å; H432-N436 WeakPolarHBondContact O-CB 3.11Å; H432-N436 VanDerWaalsContact O-CG 3.23Å; H432-N436 PolarHBondContact O-N 2.95Å; H432-N436 PolarHBondContact O-OD1 2.9Å
433	A	79.9	Confident	76.4	Confident	23 Å²	23	83.3 Å²	83.3	19%	0.19	45%	0.451	C	S	.	.	H	α-helix	trans	-62.1	-44.8	176.9	0	0	0	0	0	111.6	K429 T430 N436 F437	K429-A433 WeakPolarHBondContact O-CB 3.46Å; K429-A433 PolarHBondContact O-N 3.48Å; T430-A433 PolarHBondContact O-N 3.01Å; T430-A433 VanDerWaalsContact O-N 3.15Å; A433-N436 PolarHBondContact O-N 3.47Å; A433-F437 WeakPolarHBondContact O-CB 3.44Å; A433-F437 PolarHBondContact O-N 3.46Å
434	W	85.2	Confident	74.7	Confident	51 Å²	51	85.8 Å²	85.8	19%	0.193	48%	0.475	C	S	.	.	H	α-helix	trans	-67.9	-38.8	175.8	-82.3	91.9	0	0	0	112.5	F153 L156 T157 I160 T430 F437 I438	F153-W434 HydrophobicContact CD2-CH2 4.37Å; F153-W434 AromaticContact CD2-CZ2 3.69Å; F153-W434 HydrophobicContact CD2-CZ2 3.69Å; F153-W434 HydrophobicContact CE2-CD2 4.25Å; F153-W434 AromaticContact CE2-CE2 3.48Å; F153-W434 VanDerWaalsContact CE2-CE2 3.48Å; F153-W434 HydrophobicContact CE2-CH2 4.42Å; F153-W434 AromaticContact CE2-CZ2 3.58Å; F153-W434 HydrophobicContact CE2-CZ2 3.58Å; F153-W434 AromaticContact CE2-NE1 3.46Å; F153-W434 AromaticContact CZ-NE1 3.75Å; L156-W434 HydrophobicContact CB-CH2 4.11Å; L156-W434 HydrophobicContact CB-CZ2 3.95Å; L156-W434 HydrophobicContact CD1-CH2 4.23Å; T157-W434 PolarHBondContact OG1-NE1 3.38Å; I160-W434 HydrophobicContact CD1-CD2 4.11Å; I160-W434 HydrophobicContact CD1-CE3 4.33Å; I160-W434 HydrophobicContact CD1-CH2 4.26Å; I160-W434 HydrophobicContact CD1-CZ2 4.02Å; I160-W434 HydrophobicContact CD1-CZ3 4.4Å; T430-W434 VanDerWaalsContact CG2-CD1 3.48Å; T430-W434 VanDerWaalsContact O-CD1 3.26Å; T430-W434 PolarHBondContact O-N 3.1Å; W434-F437 PolarHBondContact O-N 3.2Å; W434-I438 HydrophobicContact CE3-CD1 4.01Å; W434-I438 HydrophobicContact CE3-CG1 4.35Å; W434-I438 WeakPolarHBondContact O-CB 3.05Å; W434-I438 VanDerWaalsContact O-CG1 3.29Å; W434-I438 WeakPolarHBondContact O-CG1 3.39Å; W434-I438 PolarHBondContact O-N 3.08Å
435	K	83.7	Confident	72.9	Confident	124 Å²	124	90.8 Å²	90.8	54%	0.539	51%	0.51	S	S	.	.	H	α-helix	trans	-58.4	-49	172.3	-176	-176.9	176.7	177.2	0	110.2	V431 H432 F437 I438 F439	V431-K435 VanDerWaalsContact O-CB 3.22Å; V431-K435 WeakPolarHBondContact O-CB 3.23Å; V431-K435 PolarHBondContact O-N 3.16Å; H432-K435 PolarHBondContact O-N 3.42Å; K435-F437 VanDerWaalsContact C-N 3.33Å; K435-F437 PolarHBondContact O-N 3.5Å; K435-I438 PolarHBondContact O-N 3.38Å; K435-F439 HydrophobicContact CB-CD2 4.34Å; K435-F439 HydrophobicContact CG-CD2 3.58Å; K435-F439 HydrophobicContact CG-CE2 4.07Å; K435-F439 HydrophobicContact CG-CG 4.47Å; K435-F439 VanDerWaalsContact O-CB 3.24Å; K435-F439 WeakPolarHBondContact O-CB 3Å; K435-F439 VanDerWaalsContact O-CD2 3.27Å; K435-F439 WeakPolarHBondContact O-CD2 3.26Å; K435-F439 PolarHBondContact O-N 3.29Å
436	N	80.8	Confident	70.8	Confident	99 Å²	99	95 Å²	95	53%	0.529	55%	0.545	S	S	.	.	H	α-helix	trans	-65.1	-38.7	178.9	-67.2	-7.7	0	0	0	111.8	H432 A433 C440	H432-N436 WeakPolarHBondContact O-CB 3.11Å; H432-N436 VanDerWaalsContact O-CG 3.23Å; H432-N436 PolarHBondContact O-N 2.95Å; H432-N436 PolarHBondContact O-OD1 2.9Å; A433-N436 PolarHBondContact O-N 3.47Å; N436-C440 WeakPolarHBondContact O-CA 3.48Å; N436-C440 WeakPolarHBondContact O-CB 3.29Å; N436-C440 PolarHBondContact O-N 3.21Å
437	F	82.5	Confident	68.9	Low	116 Å²	116	95 Å²	95	51%	0.509	55%	0.552	S	S	.	*	H	α-helix	trans	-66.4	-45	177.1	-176.3	-102.5	0	0	0	112.6	I160 A433 W434 K435 G441	I160-F437 HydrophobicContact CD1-CB 4.35Å; I160-F437 HydrophobicContact CD1-CD1 4.07Å; I160-F437 HydrophobicContact CD1-CD2 4.42Å; I160-F437 HydrophobicContact CD1-CG 4.02Å; I160-F437 HydrophobicContact CG1-CD2 4.26Å; I160-F437 HydrophobicContact CG1-CG 4.35Å; I160-F437 HydrophobicContact CG2-CB 4.45Å; A433-F437 WeakPolarHBondContact O-CB 3.44Å; A433-F437 PolarHBondContact O-N 3.46Å; W434-F437 PolarHBondContact O-N 3.2Å; K435-F437 VanDerWaalsContact C-N 3.33Å; K435-F437 PolarHBondContact O-N 3.5Å; F437-G441 WeakPolarHBondContact O-CA 3.15Å; F437-G441 PolarHBondContact O-N 3.34Å
438	I	83.4	Confident	67.2	Low	104 Å²	104	98.5 Å²	98.5	53%	0.533	57%	0.571	S	S	.	*	H	α-helix	trans	-74.7	-44.7	-178.7	-65.8	169.4	0	0	0	111.3	W434 K435	W434-I438 HydrophobicContact CE3-CD1 4.01Å; W434-I438 HydrophobicContact CE3-CG1 4.35Å; W434-I438 WeakPolarHBondContact O-CB 3.05Å; W434-I438 VanDerWaalsContact O-CG1 3.29Å; W434-I438 WeakPolarHBondContact O-CG1 3.39Å; W434-I438 PolarHBondContact O-N 3.08Å; K435-I438 PolarHBondContact O-N 3.38Å
439	F	75.8	Confident	65.3	Low	157 Å²	157	104.5 Å²	104.5	69%	0.689	59%	0.585	S	S	*	*	H	α-helix	trans	-89.9	-20.8	-173.7	-68.7	-84.3	0	0	0	114.2	K435	K435-F439 HydrophobicContact CB-CD2 4.34Å; K435-F439 HydrophobicContact CG-CD2 3.58Å; K435-F439 HydrophobicContact CG-CE2 4.07Å; K435-F439 HydrophobicContact CG-CG 4.47Å; K435-F439 VanDerWaalsContact O-CB 3.24Å; K435-F439 WeakPolarHBondContact O-CB 3Å; K435-F439 VanDerWaalsContact O-CD2 3.27Å; K435-F439 WeakPolarHBondContact O-CD2 3.26Å; K435-F439 PolarHBondContact O-N 3.29Å
440	C	63.6	Low	63.2	Low	79 Å²	79	104.7 Å²	104.7	53%	0.534	59%	0.592	S	S	.	*	H	α-helix	trans	-112.8	-6.6	174.1	-58.6	0	0	0	0	113.5	N436 M442 C443	N436-C440 WeakPolarHBondContact O-CA 3.48Å; N436-C440 WeakPolarHBondContact O-CB 3.29Å; N436-C440 PolarHBondContact O-N 3.21Å; C440-M442 VanDerWaalsContact C-N 3.27Å; C440-M442 PolarHBondContact O-N 3.36Å; C440-C443 PolarHBondContact O-N 3.29Å
441	G	54.9	Low	61.2	Low	56 Å²	56	110.3 Å²	110.3	58%	0.577	63%	0.628	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.2	-4	-179.4	0	0	0	0	0	115.9	F437	F437-G441 WeakPolarHBondContact O-CA 3.15Å; F437-G441 PolarHBondContact O-N 3.34Å
442	M	53.6	Low	59.2	Low	183 Å²	183	113.4 Å²	113.4	90%	0.901	64%	0.64	S	S	*	*	T	Hydrogen-bonded Turn	trans	-111.8	6.1	169.1	-71.2	-174.3	68.5	0	0	113.6	C440	C440-M442 VanDerWaalsContact C-N 3.27Å; C440-M442 PolarHBondContact O-N 3.36Å
443	C	44.7	Very low	57.2	Low	99 Å²	99	116 Å²	116	67%	0.669	65%	0.652	S	S	*	*	S	Bend	trans	-125.1	107	171.1	-68.3	0	0	0	0	109.3	C440	C440-C443 PolarHBondContact O-N 3.29Å
444	S	49.2	Very low	55.1	Low	113 Å²	113	120.5 Å²	120.5	79%	0.79	68%	0.68	S	S	*	*			trans	10.2	141.3	158.9	-87.1	0	0	0	0	120.5
445	S	44.1	Very low	52.6	Low	108 Å²	108	123.1 Å²	123.1	76%	0.755	71%	0.706	S	S	*	*	S	Bend	trans	37.3	108.5	140.8	-53.2	0	0	0	0	116.4
446	A	37.9	Very low	50.4	Low	89 Å²	89	124 Å²	124	74%	0.736	72%	0.722	S	S	*	*			trans	-40.9	132.7	169.2	0	0	0	0	0	111.3	V448	A446-V448 PolarHBondContact O-N 2.95Å; A446-V448 VanDerWaalsContact O-N 3.1Å
447	P	43.5	Very low	48.1	Very low	123 Å²	123	129.8 Å²	129.8	80%	0.799	74%	0.736	S	S	*	*			trans	-62.8	121	167.2	24.4	-26	0	0	0	106.6	K449	P447-K449 PolarHBondContact O-N 3.45Å
448	V	44.4	Very low	45.8	Very low	122 Å²	122	130 Å²	130	74%	0.739	75%	0.749	S	S	*	*			trans	-51.1	114.9	163.3	174.1	0	0	0	0	105.7	A446 N450	A446-V448 PolarHBondContact O-N 2.95Å; A446-V448 VanDerWaalsContact O-N 3.1Å; V448-N450 PolarHBondContact O-N 3.48Å
449	K	38.9	Very low	43.4	Very low	195 Å²	195	133.3 Å²	133.3	85%	0.848	77%	0.767	S	S	*	*			trans	-59	106.7	164.7	-103.7	-176.9	173.5	-177.5	0	105.8	P447	P447-K449 PolarHBondContact O-N 3.45Å
450	N	35.8	Very low	41.7	Very low	135 Å²	135	134 Å²	134	72%	0.722	78%	0.777	S	S	*	*	P	Polyproline II helix	trans	-52.6	133.5	164.4	-73.2	-26.3	0	0	0	107.6	V448 I452	V448-N450 PolarHBondContact O-N 3.48Å; N450-I452 PolarHBondContact O-N 3.47Å
451	P	39	Very low	40.6	Very low	123 Å²	123	138.9 Å²	138.9	80%	0.799	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-54.2	126.2	172.6	-19.9	30.2	0	0	0	108.6	E453	P451-E453 PolarHBondContact O-N 3.31Å
452	I	40.2	Very low	39.8	Very low	164 Å²	164	141.7 Å²	141.7	84%	0.841	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-61.2	119.8	169.3	-66.2	169.7	0	0	0	106.3	N450	N450-I452 PolarHBondContact O-N 3.47Å
453	E	39.3	Very low	39.1	Very low	173 Å²	173	138.9 Å²	138.9	81%	0.808	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-49.2	127.8	169.5	-150.5	171.8	-162.1	0	0	109.3	P451 S455	P451-E453 PolarHBondContact O-N 3.31Å; E453-S455 PolarHBondContact O-N 2.99Å; E453-S455 VanDerWaalsContact O-N 3.08Å
454	P	36.6	Very low	39.1	Very low	118 Å²	118	141.5 Å²	141.5	77%	0.766	81%	0.808	S	S	*	*			trans	-67.1	114.8	-179.6	24.9	-30.4	0	0	0	109.6	T456	P454-T456 PolarHBondContact O-N 2.95Å; P454-T456 VanDerWaalsContact O-N 3.12Å
455	S	32	Very low	38.8	Very low	106 Å²	106	140.1 Å²	140.1	74%	0.741	80%	0.804	S	S	*	*			trans	-49.3	116.1	164.1	168.9	0	0	0	0	109.5	E453 R457	E453-S455 PolarHBondContact O-N 2.99Å; E453-S455 VanDerWaalsContact O-N 3.08Å; S455-R457 PolarHBondContact O-N 3.35Å
456	T	38.3	Very low	38.8	Very low	142 Å²	142	140.9 Å²	140.9	87%	0.871	81%	0.806	S	S	*	*			trans	-58.4	99.5	166.4	18.3	0	0	0	0	109.2	P454	P454-T456 PolarHBondContact O-N 2.95Å; P454-T456 VanDerWaalsContact O-N 3.12Å
457	R	32.5	Very low	39	Very low	221 Å²	221	142.3 Å²	142.3	83%	0.834	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-90.5	138.1	156	-109.3	-175.6	-162.7	-158.2	3.5	108.7	S455 L459	S455-R457 PolarHBondContact O-N 3.35Å; R457-L459 PolarHBondContact O-N 3.47Å
458	P	34.1	Very low	39	Very low	120 Å²	120	142.5 Å²	142.5	78%	0.779	81%	0.809	S	S	*	*	P	Polyproline II helix	trans	-62.7	132	-179.5	-16.4	29	0	0	0	111.3	L460	P458-L460 PolarHBondContact O-N 3.37Å
459	L	32.2	Very low	38.8	Very low	174 Å²	174	145.7 Å²	145.7	91%	0.911	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-61.3	120.5	166.7	-82.2	151	0	0	0	108.9	R457	R457-L459 PolarHBondContact O-N 3.47Å
460	L	40.8	Very low	38.9	Very low	170 Å²	170	142 Å²	142	89%	0.89	81%	0.812	S	S	*	*	P	Polyproline II helix	trans	-69.5	135.9	157	-95.5	103.5	0	0	0	108.6	P458	P458-L460 PolarHBondContact O-N 3.37Å
461	E	40.7	Very low	39	Very low	183 Å²	183	140.8 Å²	140.8	86%	0.855	81%	0.811	S	S	*	*	P	Polyproline II helix	trans	-53.7	146.1	173.7	-108	171.4	155.7	0	0	112.6
462	P	38.3	Very low	39	Very low	114 Å²	114	141.9 Å²	141.9	74%	0.74	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-78.6	140.1	173.4	10.1	4.8	0	0	0	111.2
463	P	39.6	Very low	38.7	Very low	125 Å²	125	144.2 Å²	144.2	81%	0.812	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-73.7	129.9	171.5	27.6	-29	0	0	0	111.3	A465	P463-A465 PolarHBondContact O-N 3.07Å; P463-A465 VanDerWaalsContact O-N 3.16Å
464	T	43	Very low	38.4	Very low	153 Å²	153	144.4 Å²	144.4	94%	0.939	82%	0.818	S	S	*	*			trans	-69.7	93.5	171.9	6.2	0	0	0	0	110.5
465	A	43.1	Very low	38.4	Very low	84 Å²	84	147.9 Å²	147.9	69%	0.694	83%	0.825	S	S	*	*			trans	-150.9	131.8	161.8	0	0	0	0	0	110.9	P463	P463-A465 PolarHBondContact O-N 3.07Å; P463-A465 VanDerWaalsContact O-N 3.16Å
466	P	45.7	Very low	38.4	Very low	125 Å²	125	151.6 Å²	151.6	81%	0.812	83%	0.832	S	S	*	*	P	Polyproline II helix	trans	-77	149.4	177.1	23.9	-20.6	0	0	0	112.1
467	P	42.1	Very low	38.1	Very low	119 Å²	119	149.6 Å²	149.6	77%	0.773	83%	0.83	S	S	*	*	P	Polyproline II helix	trans	-77	147.7	-176.2	30.1	-33.3	0	0	0	112.8
468	P	42.3	Very low	38.3	Very low	126 Å²	126	145.8 Å²	145.8	82%	0.818	83%	0.832	S	S	*	*	P	Polyproline II helix	trans	-76.5	152.3	174.3	30.8	-32.3	0	0	0	112.3
469	Q	41.6	Very low	38.1	Very low	190 Å²	190	147.2 Å²	147.2	89%	0.888	83%	0.833	S	S	*	*	P	Polyproline II helix	trans	-68.8	147.7	-176.8	-69.2	-163.1	-16.2	0	0	113.7
470	P	40.9	Very low	38.2	Very low	116 Å²	116	144 Å²	144	75%	0.753	82%	0.822	S	S	*	*	P	Polyproline II helix	trans	-78.8	149	178.5	31	-32.9	0	0	0	112.8
471	P	37.3	Very low	37.8	Very low	110 Å²	110	144.3 Å²	144.3	71%	0.714	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-74.8	145.7	174.8	29.7	-32.1	0	0	0	112.2	Y473	P471-Y473 PolarHBondContact O-N 3.2Å
472	V	38.8	Very low	37.5	Very low	147 Å²	147	143.1 Å²	143.1	89%	0.891	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-67.9	121.2	177.7	179	0	0	0	0	110.2
473	Y	33.8	Very low	37.2	Very low	212 Å²	212	142.2 Å²	142.2	83%	0.831	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-89.5	122.9	170.9	-92.1	-90.2	0	0	0	110.9	P471	P471-Y473 PolarHBondContact O-N 3.2Å
474	M	32.9	Very low	36.8	Very low	177 Å²	177	147.7 Å²	147.7	87%	0.872	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-75.8	128.9	168.9	-150.2	172.5	-154.8	0	0	109
475	Q	36.1	Very low	36.1	Very low	192 Å²	192	151.6 Å²	151.6	90%	0.897	82%	0.817	S	S	*	*	P	Polyproline II helix	trans	-74.7	131.5	175.1	-78.4	-174.8	-26.1	0	0	111
476	M	32.3	Very low	36.1	Very low	183 Å²	183	153.5 Å²	153.5	90%	0.901	82%	0.822	S	S	*	*			trans	-131.1	115.6	157.1	-84.3	-169.7	179.4	0	0	111.3
477	A	32.1	Very low	35.8	Very low	101 Å²	101	152.9 Å²	152.9	84%	0.835	82%	0.821	S	S	*	*			trans	29	125.6	149.2	0	0	0	0	0	121.1
478	T	37	Very low	35.8	Very low	140 Å²	140	157 Å²	157	86%	0.859	83%	0.827	S	S	*	*			trans	-63.4	137.1	163.5	48.3	0	0	0	0	113.3
479	N	29.2	Very low	35.9	Very low	151 Å²	151	157.4 Å²	157.4	81%	0.807	83%	0.827	S	S	*	*			trans	-146.7	124.8	146.3	-156.4	4.5	0	0	0	110.2
480	P	35.7	Very low	35.9	Very low	105 Å²	105	158.2 Å²	158.2	68%	0.682	84%	0.844	S	S	*	*			trans	-100	116	-174.5	33.9	-23.4	0	0	0	110.9
481	Q	32.2	Very low	35.7	Very low	178 Å²	178	160.3 Å²	160.3	83%	0.832	85%	0.849	S	S	*	*			trans	-165	131.7	152.7	-110.7	148.8	6.5	0	0	114
482	N	33.1	Very low	35.6	Very low	157 Å²	157	162.9 Å²	162.9	84%	0.84	86%	0.856	S	S	*	*			trans	89	96.6	157.4	-62.3	-11.4	0	0	0	119.2
483	S	33.5	Very low	35.4	Very low	96 Å²	96	163.8 Å²	163.8	67%	0.671	85%	0.854	S	S	*	*			trans	-65.2	159.4	166.3	45	0	0	0	0	114.1
484	W	29.6	Very low	35.5	Very low	239 Å²	239	161 Å²	161	91%	0.905	86%	0.855	S	S	*	*			trans	97.7	90.1	165.8	-60.2	96.8	0	0	0	118.4
485	R	28.5	Very low	35.7	Very low	236 Å²	236	160 Å²	160	89%	0.891	85%	0.854	S	S	*	*			trans	-135.8	132.8	141.9	-80.5	-167.5	-170.3	-153	3.3	109.6
486	P	43	Very low	35.6	Very low	123 Å²	123	157.9 Å²	157.9	80%	0.799	85%	0.851	S	S	*	*	P	Polyproline II helix	trans	-80.4	129.5	167.9	8.2	7.1	0	0	0	110.3	K488	P486-K488 PolarHBondContact O-N 3.49Å
487	S	39.5	Very low	35.9	Very low	113 Å²	113	156.1 Å²	156.1	79%	0.79	85%	0.848	S	S	*	*	P	Polyproline II helix	trans	-62.6	122.7	-178.8	-58.7	0	0	0	0	112.5
488	K	42	Very low	36.2	Very low	204 Å²	204	160.3 Å²	160.3	89%	0.887	85%	0.849	S	S	*	*	P	Polyproline II helix	trans	-74.1	116.1	151.6	-78.8	177.8	175.1	177.5	0	106.9	P486	P486-K488 PolarHBondContact O-N 3.49Å
489	V	45.2	Very low	36.1	Very low	135 Å²	135	162 Å²	162	82%	0.818	85%	0.848	S	S	*	*	P	Polyproline II helix	trans	-96.9	128.2	163.6	-176.6	0	0	0	0	107
490	V	41.9	Very low	36.7	Very low	207 Å²	207	163 Å²	163	100%	1.255	85%	0.852	S	S	*	*			trans	-66	0	-173.9	172.7	0	0	0	0	112

Retrieved 490 of 490 residues in 302 ms (Link to these results)

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