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Natural resistance-associated macrophage protein 1

Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

AlphaFold DB , UniProt , Accession A0A087WNR0, Species MOUSE (Mus musculus, Mouse), Gene Slc11a1, Length 507 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.4	Very low	29.8	Very low	227 Å²	227	148.3 Å²	148.3	100%	1.118	80%	0.799	S	S	*	*				0	108.8	0	-67.7	163.3	174	0	0	105.4
2	I	26.8	Very low	29.6	Very low	161 Å²	161	155.2 Å²	155.2	83%	0.826	81%	0.805	S	S	*	*				62.5	120.8	67.2	-56.2	169.9	0	0	0	107.7
3	S	27.1	Very low	29.8	Very low	109 Å²	109	152.8 Å²	152.8	76%	0.762	81%	0.805	S	S	*	*			cis	-155.7	178	25	-109.6	0	0	0	0	109.1
4	D	28.6	Very low	29.3	Very low	126 Å²	126	150.1 Å²	150.1	67%	0.674	81%	0.805	S	S	*	*			cis	-174.5	177.9	-9.1	168.6	39.4	0	0	0	108.1
5	K	30.6	Very low	29	Very low	183 Å²	183	154.4 Å²	154.4	80%	0.796	81%	0.808	S	S	*	*			trans	109.1	98.4	152.6	-58.9	-169.9	176.1	176.1	0	120.4
6	S	25.9	Very low	28.8	Very low	103 Å²	103	149.6 Å²	149.6	72%	0.72	81%	0.807	S	S	*	*			trans	-79.3	-163.9	155.2	60.4	0	0	0	0	110.8
7	P	39.5	Very low	28.8	Very low	111 Å²	111	147.1 Å²	147.1	72%	0.721	80%	0.803	S	S	*	*			cis	-135.5	-140.6	-2.8	43.5	-21.6	0	0	0	110.7
8	P	38.3	Very low	28.5	Very low	96 Å²	96	147.9 Å²	147.9	62%	0.623	81%	0.805	S	S	*	*			cis	-134	160.2	-24.3	33.8	-14.1	0	0	0	117.8
9	R	26.1	Very low	28.8	Very low	232 Å²	232	146.1 Å²	146.1	88%	0.875	80%	0.804	S	S	*	*			trans	62.9	127.5	142.8	-69.2	170.3	-161.5	-148.5	5.2	122.5
10	L	26	Very low	28.6	Very low	174 Å²	174	144.6 Å²	144.6	91%	0.911	81%	0.805	S	S	*	*				-142.2	172.2	99.1	-132.5	84.9	0	0	0	111
11	S	24.2	Very low	28.6	Very low	109 Å²	109	145.4 Å²	145.4	76%	0.762	81%	0.807	S	S	*	*			trans	-113.6	152.7	-151.3	42	0	0	0	0	117.9
12	R	28.1	Very low	28.4	Very low	231 Å²	231	140.6 Å²	140.6	87%	0.872	79%	0.792	S	S	*	*			trans	-47.9	171.5	167.6	-71.1	-178.7	-178.4	-174.9	0.3	114.7
13	P	31.5	Very low	28.5	Very low	124 Å²	124	135.9 Å²	135.9	81%	0.805	78%	0.784	S	S	*	*			cis	-130.7	-172.4	21.9	32	-6.7	0	0	0	114.1
14	S	23.5	Very low	28.5	Very low	115 Å²	115	136.7 Å²	136.7	80%	0.804	79%	0.786	S	S	*	*			cis	-155.7	161.6	30.2	-164.1	0	0	0	0	114.2
15	Y	24.9	Very low	28.5	Very low	215 Å²	215	134.5 Å²	134.5	84%	0.843	79%	0.786	S	S	*	*			trans	-92	139.3	172.1	-94.6	-103.4	0	0	0	111.1
16	G	25.4	Very low	28.3	Very low	78 Å²	78	132 Å²	132	80%	0.804	79%	0.788	S	S	*	*			trans	-130.7	109.6	161.7	0	0	0	0	0	109.1
17	S	28	Very low	28.3	Very low	106 Å²	106	135.2 Å²	135.2	74%	0.741	79%	0.792	S	S	*	*			trans	-96	112.4	-176.5	-38.7	0	0	0	0	110.4
18	I	24.7	Very low	27.6	Very low	163 Å²	163	135.7 Å²	135.7	84%	0.836	80%	0.795	S	S	*	*			trans	-136.8	128.2	156.3	-58	-176.4	0	0	0	109.3
19	S	33.4	Very low	26.9	Very low	113 Å²	113	135.4 Å²	135.4	79%	0.79	80%	0.801	S	S	*	*			trans	-64.9	130.8	177	48.1	0	0	0	0	114
20	S	25.2	Very low	26.8	Very low	116 Å²	116	130.1 Å²	130.1	81%	0.811	80%	0.796	S	S	*	*			trans	-155.7	149.9	153.2	49.6	0	0	0	0	110.2
21	L	28.5	Very low	26.7	Very low	161 Å²	161	127.8 Å²	127.8	84%	0.843	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-68.3	155.4	-175.3	-79.5	82.4	0	0	0	112.1	G23	L21-G23 PolarHBondContact O-N 3.05Å
22	P	30.9	Very low	26.8	Very low	126 Å²	126	132.6 Å²	132.6	82%	0.818	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-61	124	166.7	27.3	-33.6	0	0	0	109.8
23	G	27.1	Very low	26.7	Very low	63 Å²	63	129 Å²	129	65%	0.649	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-62.9	153.9	174.7	0	0	0	0	0	111.9	L21	L21-G23 PolarHBondContact O-N 3.05Å
24	P	28.7	Very low	26.4	Very low	125 Å²	125	125.6 Å²	125.6	81%	0.812	77%	0.765	S	S	*	*	P	Polyproline II helix	trans	-64.1	148.2	-179.6	28.2	-34.8	0	0	0	111.3
25	A	27.7	Very low	26.6	Very low	80 Å²	80	127.3 Å²	127.3	66%	0.661	76%	0.755	S	S	*	*	P	Polyproline II helix	trans	-55.5	150.2	171.4	0	0	0	0	0	111.1	Q27	A25-Q27 PolarHBondContact O-N 2.86Å; A25-Q27 VanDerWaalsContact O-N 3.12Å
26	P	26.8	Very low	26.7	Very low	131 Å²	131	123.5 Å²	123.5	85%	0.851	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-57.9	120.7	179.1	23.9	-33.6	0	0	0	110.1
27	Q	25.7	Very low	26.6	Very low	170 Å²	170	123.1 Å²	123.1	79%	0.794	73%	0.733	S	S	*	*	P	Polyproline II helix	trans	-62.9	142.3	176.3	-67.2	-178.3	-8.7	0	0	109.7	A25 A29	A25-Q27 PolarHBondContact O-N 2.86Å; A25-Q27 VanDerWaalsContact O-N 3.12Å; Q27-A29 PolarHBondContact O-N 3.3Å
28	P	25.2	Very low	26.6	Very low	122 Å²	122	124.8 Å²	124.8	79%	0.792	73%	0.729	S	S	*	*	P	Polyproline II helix	trans	-59.5	130.3	168	26.8	-32.9	0	0	0	108.5
29	A	24	Very low	27.1	Very low	89 Å²	89	121.4 Å²	121.4	74%	0.736	71%	0.709	S	S	*	*	P	Polyproline II helix	trans	-57.5	135.1	179.2	0	0	0	0	0	109.8	Q27 C31	Q27-A29 PolarHBondContact O-N 3.3Å; A29-C31 PolarHBondContact O-N 3.12Å
30	P	22.9	Very low	27.3	Very low	121 Å²	121	120.2 Å²	120.2	79%	0.786	69%	0.692	S	S	*	*	P	Polyproline II helix	trans	-59.7	134.6	177.1	25	-33.1	0	0	0	109.2	R32	P30-R32 PolarHBondContact O-N 3.27Å
31	C	24.9	Very low	27.9	Very low	126 Å²	126	118.6 Å²	118.6	85%	0.851	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-58.8	116	169.5	-75.7	0	0	0	0	107.6	A29 E33	A29-C31 PolarHBondContact O-N 3.12Å; C31-E33 PolarHBondContact O-N 3.13Å
32	R	25.4	Very low	28.7	Very low	209 Å²	209	113.6 Å²	113.6	79%	0.789	65%	0.653	S	S	*	*			trans	-65.8	106.4	-179.5	-162	178.7	-163.4	170.3	4.1	107.3	P30 T34	P30-R32 PolarHBondContact O-N 3.27Å; R32-T34 PolarHBondContact O-N 3.22Å
33	E	27.2	Very low	29.5	Very low	157 Å²	157	108.3 Å²	108.3	73%	0.734	62%	0.619	S	S	*	*			trans	-54.4	130.8	177.4	-67.4	-176.7	146.4	0	0	109.1	C31 Y35	C31-E33 PolarHBondContact O-N 3.13Å; E33-Y35 PolarHBondContact O-N 3.4Å
34	T	24	Very low	30.6	Very low	52 Å²	52	106 Å²	106	32%	0.319	59%	0.592	S	S	.	*			trans	-58.7	133.5	175.4	-46.2	0	0	0	0	108.2	R32 L36 S37	R32-T34 PolarHBondContact O-N 3.22Å; T34-L36 HydrophobicContact CG2-CB 4.4Å; T34-L36 HydrophobicContact CG2-CD1 4.38Å; T34-L36 PolarHBondContact O-N 3.39Å; T34-S37 WeakPolarHBondContact O-CB 3.25Å; T34-S37 PolarHBondContact O-N 3.19Å; T34-S37 PolarHBondContact O-OG 3.34Å
35	Y	27.7	Very low	31.6	Very low	150 Å²	150	100.9 Å²	100.9	59%	0.588	56%	0.56	S	S	*	*	G	3₁₀ helix	trans	-57	-10.3	-177.2	-68.4	-83.8	0	0	0	115.3	E33 S37	E33-Y35 PolarHBondContact O-N 3.4Å; Y35-S37 PolarHBondContact O-N 3.48Å
36	L	26.8	Very low	32.8	Very low	135 Å²	135	99.6 Å²	99.6	71%	0.707	54%	0.543	S	S	*	.	G	3₁₀ helix	trans	-69	-11.7	167.6	-82.8	155.1	0	0	0	114.2	T34	T34-L36 HydrophobicContact CG2-CB 4.4Å; T34-L36 HydrophobicContact CG2-CD1 4.38Å; T34-L36 PolarHBondContact O-N 3.39Å
37	S	24.4	Very low	34.7	Very low	70 Å²	70	95 Å²	95	49%	0.49	51%	0.51	S	S	.	.	G	3₁₀ helix	trans	-97.3	-8.2	-179.8	-50.5	0	0	0	0	113.7	T34 Y35 K39	T34-S37 WeakPolarHBondContact O-CB 3.25Å; T34-S37 PolarHBondContact O-N 3.19Å; T34-S37 PolarHBondContact O-OG 3.34Å; Y35-S37 PolarHBondContact O-N 3.48Å; S37-K39 PolarHBondContact O-N 3.37Å
38	E	28	Very low	36.9	Very low	141 Å²	141	87.5 Å²	87.5	66%	0.659	48%	0.475	S	S	*	.	S	Bend	trans	-70.5	105.2	-179.8	-166.7	164.1	-179.1	0	0	108.6	I40	E38-I40 PolarHBondContact O-N 2.79Å
39	K	34.8	Very low	39.6	Very low	93 Å²	93	81.7 Å²	81.7	40%	0.404	44%	0.437	S	S	.	.			trans	-56.4	106.1	-174.8	-72.3	-179.3	-178.2	174.2	0	109.8	S37 P41 D293 N295	S37-K39 PolarHBondContact O-N 3.37Å; K39-P41 VanDerWaalsContact O-CD 3.3Å; K39-P41 WeakPolarHBondContact O-CD 3.49Å; K39-D293 IonicContact NZ-OD2 3.16Å; K39-D293 PolarHBondContact NZ-OD2 3.25Å; K39-N295 HydrophobicContact CD-CB 3.72Å; K39-N295 PolarHBondContact NZ-ND2 3.29Å
40	I	38.3	Very low	42.6	Very low	87 Å²	87	81.1 Å²	81.1	45%	0.446	42%	0.416	S	S	.	.			trans	-59.2	118.5	-173.6	-59.3	172.4	0	0	0	109.3	E38 I42 P195	E38-I40 PolarHBondContact O-N 2.79Å; I40-I42 PolarHBondContact O-N 3.08Å; I40-P195 HydrophobicContact CD1-CB 4.14Å; I40-P195 HydrophobicContact CG1-CB 4.03Å; I40-P195 HydrophobicContact CG2-CB 4.09Å
41	P	36.8	Very low	45.6	Very low	83 Å²	83	75.8 Å²	75.8	54%	0.539	38%	0.382	S	S	.	.			trans	-64.1	125.9	169.5	-17.5	31.7	0	0	0	108.4	K39 P43	K39-P41 VanDerWaalsContact O-CD 3.3Å; K39-P41 WeakPolarHBondContact O-CD 3.49Å; P41-P43 WeakPolarHBondContact O-CD 3.26Å; P41-P43 VanDerWaalsContact O-N 3.16Å
42	I	45.2	Very low	48.7	Very low	55 Å²	55	70.2 Å²	70.2	28%	0.282	34%	0.343	S	S	.	.			trans	-65.1	114.8	-176.6	-62.2	166	0	0	0	109	I40 F266 V299	I40-I42 PolarHBondContact O-N 3.08Å; I42-F266 HydrophobicContact CD1-CB 3.94Å; I42-V299 HydrophobicContact CD1-CG2 3.6Å; I42-V299 HydrophobicContact CG1-CG2 4.14Å
43	P	48.9	Very low	51.8	Low	16 Å²	16	62.5 Å²	62.5	10%	0.104	32%	0.317	C	S	.	.			trans	-61.7	143.9	163.6	28.6	-33.8	0	0	0	107.9	P41 A45 Q47 L48 E196	P41-P43 WeakPolarHBondContact O-CD 3.26Å; P41-P43 VanDerWaalsContact O-N 3.16Å; P43-A45 PolarHBondContact O-N 3.08Å; P43-Q47 HydrophobicContact CB-CB 4.35Å; P43-L48 HydrophobicContact CG-CD1 4.16Å; P43-E196 HydrophobicContact CB-CG 4.41Å; P43-E196 HydrophobicContact CG-CG 4.22Å
44	S	50	Low	54.8	Low	14 Å²	14	62.7 Å²	62.7	10%	0.098	31%	0.311	C	S	.	.			trans	-54	137.1	-179.5	72.7	0	0	0	0	109.4	D46 Q47	S44-D46 WeakPolarHBondContact CB-OD2 3.48Å; S44-D46 PolarHBondContact O-N 3.34Å; S44-D46 PolarHBondContact OG-OD2 2.67Å; S44-Q47 VanDerWaalsContact N-NE2 3.16Å; S44-Q47 WeakPolarHBondContact O-CB 3.44Å; S44-Q47 WeakPolarHBondContact O-CG 3.25Å; S44-Q47 PolarHBondContact O-N 2.83Å; S44-Q47 WeakPolarHBondContact OG-CG 3.35Å; S44-Q47 PolarHBondContact OG-NE2 3.48Å
45	A	49.5	Very low	57.9	Low	17 Å²	17	60.3 Å²	60.3	14%	0.14	30%	0.297	C	S	.	.	G	3₁₀ helix	trans	-56.8	-26.1	-170	0	0	0	0	0	112.9	P43 Q47 L49	P43-A45 PolarHBondContact O-N 3.08Å; A45-Q47 PolarHBondContact O-N 3.45Å; A45-Q47 VanDerWaalsContact O-N 3.17Å; A45-L49 WeakPolarHBondContact O-CG 3.32Å
46	D	53.3	Low	61	Low	54 Å²	54	53.8 Å²	53.8	29%	0.289	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-42.5	-37.8	164.8	-28.7	-44.2	0	0	0	114.3	S44 L48 G183	S44-D46 WeakPolarHBondContact CB-OD2 3.48Å; S44-D46 PolarHBondContact O-N 3.34Å; S44-D46 PolarHBondContact OG-OD2 2.67Å; D46-L48 PolarHBondContact O-N 3.07Å; D46-G183 CarbonylContact O-C 3.51Å; D46-G183 WeakPolarHBondContact O-CA 3.29Å
47	Q	65.7	Low	64.2	Low	35 Å²	35	50.1 Å²	50.1	16%	0.164	26%	0.256	C	S	.	.	G	3₁₀ helix	trans	-79.6	-19.7	-165.3	-63.3	177.2	37.7	0	0	114.6	P43 S44 A45 W50	P43-Q47 HydrophobicContact CB-CB 4.35Å; S44-Q47 VanDerWaalsContact N-NE2 3.16Å; S44-Q47 WeakPolarHBondContact O-CB 3.44Å; S44-Q47 WeakPolarHBondContact O-CG 3.25Å; S44-Q47 PolarHBondContact O-N 2.83Å; S44-Q47 WeakPolarHBondContact OG-CG 3.35Å; S44-Q47 PolarHBondContact OG-NE2 3.48Å; A45-Q47 PolarHBondContact O-N 3.45Å; A45-Q47 VanDerWaalsContact O-N 3.17Å; Q47-W50 PolarHBondContact O-NE1 2.96Å
48	L	72.6	Confident	67.3	Low	11 Å²	11	47.8 Å²	47.8	6%	0.058	24%	0.238	C	C	.	.	T	Hydrogen-bonded Turn	trans	-113.8	-2.3	-178.4	-66.3	173	0	0	0	113.2	P43 D46 W50 V51 L52 Q199 A200 I203	P43-L48 HydrophobicContact CG-CD1 4.16Å; D46-L48 PolarHBondContact O-N 3.07Å; L48-W50 VanDerWaalsContact C-N 3.33Å; L48-W50 PolarHBondContact O-N 3.43Å; L48-V51 HydrophobicContact CD2-CG2 3.99Å; L48-V51 WeakPolarHBondContact O-CA 3.36Å; L48-V51 VanDerWaalsContact O-CB 3.29Å; L48-V51 WeakPolarHBondContact O-CB 3.23Å; L48-V51 PolarHBondContact O-N 2.76Å; L48-L52 PolarHBondContact O-N 3.43Å; L48-L52 VanDerWaalsContact O-N 3.14Å; L48-Q199 HydrophobicContact CD1-CB 4.33Å; L48-Q199 VanDerWaalsContact CD1-CD 3.5Å; L48-Q199 HydrophobicContact CD1-CG 3.9Å; L48-A200 HydrophobicContact CD2-CB 4.01Å; L48-I203 HydrophobicContact CB-CD1 3.97Å; L48-I203 HydrophobicContact CD1-CD1 4.02Å; L48-I203 HydrophobicContact CG-CD1 4.47Å
49	L	82	Confident	70.4	Confident	0 Å²	0	41.2 Å²	41.2	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-64	-33	178.3	-85	163.6	0	0	0	113.4	A45 V51 L52 L53 L180 L184 L256 M259	A45-L49 WeakPolarHBondContact O-CG 3.32Å; L49-V51 VanDerWaalsContact C-N 3.3Å; L49-V51 PolarHBondContact O-N 3.15Å; L49-L52 HydrophobicContact CD2-CD2 4.25Å; L49-L52 WeakPolarHBondContact O-CB 3.37Å; L49-L52 PolarHBondContact O-N 3.29Å; L49-L53 PolarHBondContact O-N 3.15Å; L49-L53 VanDerWaalsContact O-N 3.12Å; L49-L180 HydrophobicContact CD1-CD2 3.69Å; L49-L184 HydrophobicContact CB-CD1 4.45Å; L49-L256 HydrophobicContact CD2-CD1 3.47Å; L49-L256 VanDerWaalsContact CD2-CD1 3.47Å; L49-M259 HydrophobicContact CD2-CB 4.29Å
50	W	85.9	Confident	73.2	Confident	77 Å²	77	38.8 Å²	38.8	29%	0.292	20%	0.199	S	C	.	.	H	α-helix	trans	-65	-34.2	170.9	71.6	-87	0	0	0	111.8	Q47 L48 L53 W54 G183 P187	Q47-W50 PolarHBondContact O-NE1 2.96Å; L48-W50 VanDerWaalsContact C-N 3.33Å; L48-W50 PolarHBondContact O-N 3.43Å; W50-L53 PolarHBondContact O-N 3.06Å; W50-W54 AromaticContact CE3-CD1 3.97Å; W50-W54 VanDerWaalsContact O-CD1 3.24Å; W50-W54 PolarHBondContact O-N 3.04Å; W50-G183 PolarHBondContact N-O 2.75Å; W50-P187 HydrophobicContact CD2-CB 3.82Å; W50-P187 HydrophobicContact CE3-CB 4.11Å; W50-P187 HydrophobicContact CG-CB 4.12Å
51	V	87.3	Confident	75.8	Confident	10 Å²	10	37.3 Å²	37.3	6%	0.061	19%	0.192	C	C	.	.	H	α-helix	trans	-64.5	-44.7	175	-173.5	0	0	0	0	109.6	L48 L49 L53 W54 A55 A200 I203 V204	L48-V51 HydrophobicContact CD2-CG2 3.99Å; L48-V51 WeakPolarHBondContact O-CA 3.36Å; L48-V51 VanDerWaalsContact O-CB 3.29Å; L48-V51 WeakPolarHBondContact O-CB 3.23Å; L48-V51 PolarHBondContact O-N 2.76Å; L49-V51 VanDerWaalsContact C-N 3.3Å; L49-V51 PolarHBondContact O-N 3.15Å; V51-L53 VanDerWaalsContact C-N 3.34Å; V51-L53 PolarHBondContact O-N 2.94Å; V51-W54 PolarHBondContact O-N 3.43Å; V51-A55 WeakPolarHBondContact O-CB 3.17Å; V51-A55 PolarHBondContact O-N 2.65Å; V51-A200 HydrophobicContact CG1-CB 4.24Å; V51-A200 HydrophobicContact CG2-CB 4.25Å; V51-I203 HydrophobicContact CG1-CB 4.48Å; V51-I203 HydrophobicContact CG1-CG2 4.16Å; V51-V204 HydrophobicContact CG1-CG2 4.04Å
52	L	88.5	Confident	78.5	Confident	9 Å²	9	33.4 Å²	33.4	5%	0.047	17%	0.167	C	C	.	.	H	α-helix	trans	-55.3	-47.2	175.3	-169	85.9	0	0	0	111.9	L48 L49 T56 I203 I207 F252 N255 L256 M259	L48-L52 PolarHBondContact O-N 3.43Å; L48-L52 VanDerWaalsContact O-N 3.14Å; L49-L52 HydrophobicContact CD2-CD2 4.25Å; L49-L52 WeakPolarHBondContact O-CB 3.37Å; L49-L52 PolarHBondContact O-N 3.29Å; L52-T56 WeakPolarHBondContact O-CB 3.07Å; L52-T56 PolarHBondContact O-N 3.24Å; L52-T56 PolarHBondContact O-OG1 3.49Å; L52-I203 HydrophobicContact CD1-CG2 4.31Å; L52-I207 HydrophobicContact CD1-CD1 3.65Å; L52-I207 HydrophobicContact CG-CD1 4.17Å; L52-F252 HydrophobicContact CD2-CD2 4.24Å; L52-F252 HydrophobicContact CD2-CE2 4.13Å; L52-F252 HydrophobicContact CG-CD2 4.5Å; L52-N255 HydrophobicContact CD1-CB 3.86Å; L52-N255 HydrophobicContact CD2-CB 4.05Å; L52-N255 HydrophobicContact CG-CB 4.39Å; L52-L256 HydrophobicContact CD2-CB 4.35Å; L52-M259 HydrophobicContact CD1-CG 4.41Å
53	L	90.8	Very high	80.7	Confident	47 Å²	47	31.8 Å²	31.8	25%	0.246	16%	0.158	C	C	.	.	H	α-helix	trans	-62.9	-53.9	177.8	-180	69.2	0	0	0	111.4	L49 W50 V51 A55 T56 V57 L184 F252	L49-L53 PolarHBondContact O-N 3.15Å; L49-L53 VanDerWaalsContact O-N 3.12Å; W50-L53 PolarHBondContact O-N 3.06Å; V51-L53 VanDerWaalsContact C-N 3.34Å; V51-L53 PolarHBondContact O-N 2.94Å; L53-A55 PolarHBondContact O-N 3.46Å; L53-T56 WeakPolarHBondContact O-CB 3.45Å; L53-T56 PolarHBondContact O-N 3.01Å; L53-V57 WeakPolarHBondContact O-CG2 3.08Å; L53-V57 PolarHBondContact O-N 3.45Å; L53-L184 HydrophobicContact CB-CD1 4.27Å; L53-L184 HydrophobicContact CB-CG 4.36Å; L53-L184 HydrophobicContact CD2-CD2 4.22Å; L53-L184 HydrophobicContact CD2-CG 4.09Å; L53-F252 HydrophobicContact CB-CE2 4.04Å; L53-F252 HydrophobicContact CD1-CD2 4.45Å; L53-F252 HydrophobicContact CD1-CE1 4.41Å; L53-F252 HydrophobicContact CD1-CE2 3.73Å; L53-F252 HydrophobicContact CD1-CZ 3.71Å
54	W	89.9	Confident	82.9	Confident	160 Å²	160	35.9 Å²	35.9	61%	0.606	17%	0.171	S	C	*	.	H	α-helix	trans	-68.5	-33	-176.2	-78.8	105.6	0	0	0	113.1	W50 V51 V57 L58	W50-W54 AromaticContact CE3-CD1 3.97Å; W50-W54 VanDerWaalsContact O-CD1 3.24Å; W50-W54 PolarHBondContact O-N 3.04Å; V51-W54 PolarHBondContact O-N 3.43Å; W54-V57 HydrophobicContact CE3-CB 4.48Å; W54-V57 HydrophobicContact CE3-CG1 4.36Å; W54-V57 HydrophobicContact CZ3-CG1 4.41Å; W54-V57 PolarHBondContact O-N 3.46Å; W54-L58 VanDerWaalsContact O-CB 3.24Å; W54-L58 WeakPolarHBondContact O-CB 3.39Å; W54-L58 PolarHBondContact O-N 2.84Å
55	A	90.4	Very high	84.9	Confident	3 Å²	3	35.6 Å²	35.6	3%	0.025	17%	0.168	C	C	.	.	H	α-helix	trans	-66.5	-38	171.7	0	0	0	0	0	111.7	V51 L53 L58 G59 V204 I207 I208	V51-A55 WeakPolarHBondContact O-CB 3.17Å; V51-A55 PolarHBondContact O-N 2.65Å; L53-A55 PolarHBondContact O-N 3.46Å; A55-L58 PolarHBondContact O-N 3.08Å; A55-G59 PolarHBondContact O-N 2.96Å; A55-V204 HydrophobicContact CB-CG2 4.08Å; A55-I207 HydrophobicContact CB-CB 4.33Å; A55-I207 HydrophobicContact CB-CD1 3.66Å; A55-I207 HydrophobicContact CB-CG2 4.45Å; A55-I208 WeakPolarHBondContact O-CD1 3.31Å
56	T	92.5	Very high	87	Confident	13 Å²	13	34.8 Å²	34.8	8%	0.08	16%	0.162	C	C	.	.	H	α-helix	trans	-65.7	-45.8	173.2	-56.8	0	0	0	0	111.2	L52 L53 L58 G59 L60 L248 F252	L52-T56 WeakPolarHBondContact O-CB 3.07Å; L52-T56 PolarHBondContact O-N 3.24Å; L52-T56 PolarHBondContact O-OG1 3.49Å; L53-T56 WeakPolarHBondContact O-CB 3.45Å; L53-T56 PolarHBondContact O-N 3.01Å; T56-L58 VanDerWaalsContact C-N 3.3Å; T56-L58 PolarHBondContact O-N 2.9Å; T56-G59 PolarHBondContact O-N 3.29Å; T56-L60 PolarHBondContact O-N 3.19Å; T56-L248 HydrophobicContact CG2-CB 4.35Å; T56-F252 HydrophobicContact CG2-CB 3.85Å; T56-F252 HydrophobicContact CG2-CD2 4.45Å; T56-F252 HydrophobicContact CG2-CG 4.45Å
57	V	92.7	Very high	88.9	Confident	58 Å²	58	32.7 Å²	32.7	35%	0.352	15%	0.152	S	C	.	.	H	α-helix	trans	-59.6	-42.3	175.5	170.7	0	0	0	0	110.8	L53 W54 L60 L61	L53-V57 WeakPolarHBondContact O-CG2 3.08Å; L53-V57 PolarHBondContact O-N 3.45Å; W54-V57 HydrophobicContact CE3-CB 4.48Å; W54-V57 HydrophobicContact CE3-CG1 4.36Å; W54-V57 HydrophobicContact CZ3-CG1 4.41Å; W54-V57 PolarHBondContact O-N 3.46Å; V57-L60 PolarHBondContact O-N 3.28Å; V57-L61 WeakPolarHBondContact O-CG 3.34Å; V57-L61 PolarHBondContact O-N 3.24Å
58	L	91.1	Very high	90.3	Very high	21 Å²	21	32.8 Å²	32.8	11%	0.11	15%	0.151	C	C	.	.	H	α-helix	trans	-65	-42	175.6	-178.9	57.2	0	0	0	111.9	W54 A55 T56 L60 L61 C62 I208 I428 L431	W54-L58 VanDerWaalsContact O-CB 3.24Å; W54-L58 WeakPolarHBondContact O-CB 3.39Å; W54-L58 PolarHBondContact O-N 2.84Å; A55-L58 PolarHBondContact O-N 3.08Å; T56-L58 VanDerWaalsContact C-N 3.3Å; T56-L58 PolarHBondContact O-N 2.9Å; L58-L60 PolarHBondContact O-N 3.35Å; L58-L61 PolarHBondContact O-N 2.97Å; L58-C62 PolarHBondContact O-N 2.78Å; L58-C62 PolarHBondContact O-SG 3.1Å; L58-I208 HydrophobicContact CB-CD1 3.83Å; L58-I208 HydrophobicContact CD2-CD1 3.62Å; L58-I208 HydrophobicContact CG-CD1 3.56Å; L58-I428 HydrophobicContact CD1-CB 4.21Å; L58-I428 HydrophobicContact CD1-CD1 3.44Å; L58-I428 VanDerWaalsContact CD1-CD1 3.44Å; L58-I428 HydrophobicContact CD1-CG1 3.44Å; L58-I428 VanDerWaalsContact CD1-CG1 3.44Å; L58-I428 HydrophobicContact CD1-CG2 3.77Å; L58-L431 HydrophobicContact CD2-CD2 4.4Å
59	G	92.2	Very high	91.3	Very high	3 Å²	3	32.2 Å²	32.2	3%	0.031	15%	0.148	C	C	.	.	H	α-helix	trans	-56.2	-47.8	172.1	0	0	0	0	0	112.1	A55 T56 L61 C62 Q63	A55-G59 PolarHBondContact O-N 2.96Å; T56-G59 PolarHBondContact O-N 3.29Å; G59-L61 VanDerWaalsContact C-N 3.33Å; G59-L61 PolarHBondContact O-N 3.48Å; G59-C62 PolarHBondContact O-N 2.87Å; G59-Q63 WeakPolarHBondContact O-CB 3.22Å; G59-Q63 WeakPolarHBondContact O-CG 3.48Å; G59-Q63 PolarHBondContact O-N 2.97Å
60	L	94	Very high	91.8	Very high	41 Å²	41	32.2 Å²	32.2	22%	0.215	15%	0.148	C	C	.	.	H	α-helix	trans	-60.1	-41.2	176	180	61	0	0	0	112.1	T56 V57 L58 R64 A244 T245 L248	T56-L60 PolarHBondContact O-N 3.19Å; V57-L60 PolarHBondContact O-N 3.28Å; L58-L60 PolarHBondContact O-N 3.35Å; L60-R64 WeakPolarHBondContact O-CB 3.49Å; L60-R64 PolarHBondContact O-N 3.01Å; L60-A244 HydrophobicContact CD1-CB 4.12Å; L60-T245 HydrophobicContact CD2-CG2 4.36Å; L60-L248 HydrophobicContact CB-CD1 3.56Å; L60-L248 HydrophobicContact CD1-CD1 3.93Å; L60-L248 HydrophobicContact CG-CD1 4.33Å
61	L	93	Very high	92.1	Very high	56 Å²	56	28.7 Å²	28.7	29%	0.293	14%	0.135	S	C	.	.	H	α-helix	trans	-63.4	-45.1	175.5	-69.6	172.9	0	0	0	111.7	V57 L58 G59 L65 I424 I428	V57-L61 WeakPolarHBondContact O-CG 3.34Å; V57-L61 PolarHBondContact O-N 3.24Å; L58-L61 PolarHBondContact O-N 2.97Å; G59-L61 VanDerWaalsContact C-N 3.33Å; G59-L61 PolarHBondContact O-N 3.48Å; L61-L65 VanDerWaalsContact O-CG 3.31Å; L61-L65 WeakPolarHBondContact O-CG 3.36Å; L61-L65 PolarHBondContact O-N 3.22Å; L61-L65 VanDerWaalsContact O-N 3.13Å; L61-I424 HydrophobicContact CD1-CG2 4.16Å; L61-I428 HydrophobicContact CD1-CD1 4.4Å
62	C	92.3	Very high	92.3	Very high	1 Å²	1	29.3 Å²	29.3	1%	0.007	14%	0.139	C	C	.	.	H	α-helix	trans	-66.4	-46.1	178	-70.7	0	0	0	0	112.4	L58 G59 L65 A66 I213	L58-C62 PolarHBondContact O-N 2.78Å; L58-C62 PolarHBondContact O-SG 3.1Å; G59-C62 PolarHBondContact O-N 2.87Å; C62-L65 PolarHBondContact O-N 3.35Å; C62-A66 PolarHBondContact O-N 3.07Å; C62-I213 HydrophobicContact CB-CD1 4.16Å
63	Q	93.2	Very high	92.4	Very high	22 Å²	22	30.6 Å²	30.6	10%	0.103	15%	0.147	C	C	.	.	H	α-helix	trans	-62.9	-41.5	176.4	-72.6	-176.7	3.7	0	0	112.1	G59 L65 A66 A67 L248	G59-Q63 WeakPolarHBondContact O-CB 3.22Å; G59-Q63 WeakPolarHBondContact O-CG 3.48Å; G59-Q63 PolarHBondContact O-N 2.97Å; Q63-L65 VanDerWaalsContact C-N 3.3Å; Q63-L65 PolarHBondContact O-N 3.15Å; Q63-A66 WeakPolarHBondContact O-CB 3.4Å; Q63-A66 PolarHBondContact O-N 3.16Å; Q63-A67 WeakPolarHBondContact O-CB 3.44Å; Q63-A67 PolarHBondContact O-N 2.86Å; Q63-L248 VanDerWaalsContact OE1-CD1 3.29Å
64	R	93.4	Very high	92.3	Very high	102 Å²	102	29.2 Å²	29.2	39%	0.385	15%	0.145	S	C	.	.	H	α-helix	trans	-58.5	-41.5	173.8	177.5	-172.8	-179.9	-135.7	-1.3	111.9	L60 R68 L241	L60-R64 WeakPolarHBondContact O-CB 3.49Å; L60-R64 PolarHBondContact O-N 3.01Å; R64-R68 VanDerWaalsContact O-CB 3.23Å; R64-R68 WeakPolarHBondContact O-CB 3.49Å; R64-R68 PolarHBondContact O-N 3.41Å; R64-L241 HydrophobicContact CB-CD1 4.31Å; R64-L241 HydrophobicContact CG-CD1 3.95Å
65	L	93.3	Very high	92.4	Very high	7 Å²	7	25.3 Å²	25.3	4%	0.037	13%	0.132	C	C	.	.	H	α-helix	trans	-66.6	-42.3	176.5	-71.2	175.3	0	0	0	111.2	L61 C62 Q63 R68 L69 I402 L403 T406 T425	L61-L65 VanDerWaalsContact O-CG 3.31Å; L61-L65 WeakPolarHBondContact O-CG 3.36Å; L61-L65 PolarHBondContact O-N 3.22Å; L61-L65 VanDerWaalsContact O-N 3.13Å; C62-L65 PolarHBondContact O-N 3.35Å; Q63-L65 VanDerWaalsContact C-N 3.3Å; Q63-L65 PolarHBondContact O-N 3.15Å; L65-R68 PolarHBondContact O-N 3.47Å; L65-L69 PolarHBondContact O-N 3.21Å; L65-I402 HydrophobicContact CB-CG1 3.91Å; L65-L403 HydrophobicContact CD1-CD2 3.77Å; L65-T406 HydrophobicContact CB-CG2 4.03Å; L65-T406 HydrophobicContact CD2-CG2 4.18Å; L65-T406 WeakPolarHBondContact O-CG2 3.29Å; L65-T425 HydrophobicContact CD1-CG2 3.75Å
66	A	94.1	Very high	92.5	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-59.8	-51.2	175.2	0	0	0	0	0	113.1	C62 Q63 R68 L69 G70 I213 S217 I402	C62-A66 PolarHBondContact O-N 3.07Å; Q63-A66 WeakPolarHBondContact O-CB 3.4Å; Q63-A66 PolarHBondContact O-N 3.16Å; A66-R68 PolarHBondContact O-N 3.2Å; A66-L69 PolarHBondContact O-N 3.07Å; A66-G70 PolarHBondContact O-N 3.13Å; A66-I213 HydrophobicContact CB-CG2 3.93Å; A66-I213 VanDerWaalsContact CB-O 3.31Å; A66-I213 WeakPolarHBondContact CB-O 3.27Å; A66-S217 WeakPolarHBondContact O-CA 3.45Å; A66-S217 WeakPolarHBondContact O-CB 3.44Å; A66-I402 HydrophobicContact CB-CD1 4.4Å; A66-I402 HydrophobicContact CB-CG1 4.38Å
67	A	93.1	Very high	92.5	Very high	11 Å²	11	24.8 Å²	24.8	9%	0.091	13%	0.128	C	C	.	.	H	α-helix	trans	-57.8	-47.4	175.9	0	0	0	0	0	111.2	Q63 L69 G70 V71 V220 F240	Q63-A67 WeakPolarHBondContact O-CB 3.44Å; Q63-A67 PolarHBondContact O-N 2.86Å; A67-L69 VanDerWaalsContact C-N 3.35Å; A67-L69 PolarHBondContact O-N 3.25Å; A67-G70 PolarHBondContact O-N 3.1Å; A67-V71 VanDerWaalsContact O-CG2 3.29Å; A67-V71 WeakPolarHBondContact O-CG2 3.47Å; A67-V71 PolarHBondContact O-N 3.25Å; A67-V220 HydrophobicContact CB-CG1 3.81Å; A67-F240 HydrophobicContact CB-CB 4.41Å
68	R	93.4	Very high	92.5	Very high	36 Å²	36	22 Å²	22	14%	0.136	11%	0.111	C	C	.	.	H	α-helix	trans	-62.4	-37.3	179.1	-177.1	-177.3	166.4	-162.7	1.4	113.2	R64 L65 A66 V72 N237 M412 F415 A416 N417	R64-R68 VanDerWaalsContact O-CB 3.23Å; R64-R68 WeakPolarHBondContact O-CB 3.49Å; R64-R68 PolarHBondContact O-N 3.41Å; L65-R68 PolarHBondContact O-N 3.47Å; A66-R68 PolarHBondContact O-N 3.2Å; R68-V72 HydrophobicContact CG-CG2 4.27Å; R68-V72 WeakPolarHBondContact O-CB 3.3Å; R68-V72 VanDerWaalsContact O-CG2 3.24Å; R68-V72 WeakPolarHBondContact O-CG2 3.14Å; R68-V72 PolarHBondContact O-N 3.03Å; R68-N237 VanDerWaalsContact CA-OD1 3.29Å; R68-N237 WeakPolarHBondContact CA-OD1 3.46Å; R68-N237 WeakPolarHBondContact CB-OD1 3.47Å; R68-N237 WeakPolarHBondContact CG-OD1 3.43Å; R68-M412 HydrophobicContact CB-CE 4.45Å; R68-M412 HydrophobicContact CG-CE 3.71Å; R68-F415 VanDerWaalsContact CZ-O 3.31Å; R68-F415 PolarHBondContact NE-O 2.96Å; R68-F415 PolarHBondContact NH2-O 2.75Å; R68-A416 PolarHBondContact NH2-O 3.35Å; R68-N417 PolarHBondContact NH1-OD1 3.41Å
69	L	93.8	Very high	92.6	Very high	0 Å²	0	24 Å²	24	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-60.2	-49.1	173.4	-178.7	71.3	0	0	0	110.6	L65 A66 A67 T73 L77 V80 I402 F405 T406 V411 M412	L65-L69 PolarHBondContact O-N 3.21Å; A66-L69 PolarHBondContact O-N 3.07Å; A67-L69 VanDerWaalsContact C-N 3.35Å; A67-L69 PolarHBondContact O-N 3.25Å; L69-T73 HydrophobicContact CD1-CG2 3.79Å; L69-T73 HydrophobicContact CG-CG2 4.45Å; L69-T73 WeakPolarHBondContact O-CB 3.4Å; L69-T73 WeakPolarHBondContact O-CG2 3.38Å; L69-T73 PolarHBondContact O-N 2.98Å; L69-T73 PolarHBondContact O-OG1 2.96Å; L69-L77 HydrophobicContact CD2-CB 4.21Å; L69-L77 HydrophobicContact CD2-CD1 3.58Å; L69-L77 HydrophobicContact CD2-CG 4.49Å; L69-V80 HydrophobicContact CD2-CG2 4.38Å; L69-I402 HydrophobicContact CB-CD1 3.71Å; L69-I402 HydrophobicContact CD2-CD1 3.55Å; L69-I402 HydrophobicContact CG-CD1 4.21Å; L69-F405 HydrophobicContact CD1-CB 4.05Å; L69-F405 HydrophobicContact CD2-CB 4.45Å; L69-T406 HydrophobicContact CB-CG2 4.2Å; L69-V411 HydrophobicContact CD1-CG1 3.73Å; L69-M412 HydrophobicContact CD1-SD 3.69Å
70	G	92.4	Very high	92.6	Very high	0 Å²	0	24 Å²	24	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-65.7	-39.4	-179.8	0	0	0	0	0	113.8	A66 A67 G74 K75	A66-G70 PolarHBondContact O-N 3.13Å; A67-G70 PolarHBondContact O-N 3.1Å; G70-G74 WeakPolarHBondContact O-CA 3.23Å; G70-G74 PolarHBondContact O-N 3.23Å; G70-K75 WeakPolarHBondContact CA-O 3.4Å
71	V	92.7	Very high	92.5	Very high	2 Å²	2	22.1 Å²	22.1	1%	0.012	11%	0.11	C	C	.	.	H	α-helix	trans	-63.6	-51.5	176.1	174.1	0	0	0	0	111	A67 V220 R227 V233 A236 F240	A67-V71 VanDerWaalsContact O-CG2 3.29Å; A67-V71 WeakPolarHBondContact O-CG2 3.47Å; A67-V71 PolarHBondContact O-N 3.25Å; V71-V220 HydrophobicContact CG2-CB 3.88Å; V71-V220 HydrophobicContact CG2-CG1 4.08Å; V71-V220 HydrophobicContact CG2-CG2 4.19Å; V71-R227 PolarHBondContact O-NE 3.16Å; V71-V233 HydrophobicContact CG1-CG1 4.24Å; V71-A236 HydrophobicContact CG1-CB 4.01Å; V71-F240 HydrophobicContact CG2-CD2 3.47Å; V71-F240 VanDerWaalsContact CG2-CD2 3.47Å; V71-F240 HydrophobicContact CG2-CE2 3.57Å
72	V	91.7	Very high	92.3	Very high	24 Å²	24	20.8 Å²	20.8	15%	0.145	10%	0.102	C	C	.	.	H	α-helix	trans	-70.3	-46.3	-174.5	173.4	0	0	0	0	111.9	R68 V233 M412 F415	R68-V72 HydrophobicContact CG-CG2 4.27Å; R68-V72 WeakPolarHBondContact O-CB 3.3Å; R68-V72 VanDerWaalsContact O-CG2 3.24Å; R68-V72 WeakPolarHBondContact O-CG2 3.14Å; R68-V72 PolarHBondContact O-N 3.03Å; V72-V233 HydrophobicContact CG2-CG1 4.06Å; V72-M412 HydrophobicContact CB-SD 4.5Å; V72-F415 HydrophobicContact CG1-CB 4.31Å; V72-F415 HydrophobicContact CG1-CD2 4.22Å; V72-F415 HydrophobicContact CG2-CB 3.84Å; V72-F415 HydrophobicContact CG2-CD2 4.11Å; V72-F415 HydrophobicContact CG2-CG 4.01Å
73	T	89.8	Confident	92.1	Very high	35 Å²	35	22.6 Å²	22.6	22%	0.215	11%	0.111	C	C	.	.	H	α-helix	trans	-85.9	-21.1	-175.1	66.9	0	0	0	0	113.6	L69 K75 V411	L69-T73 HydrophobicContact CD1-CG2 3.79Å; L69-T73 HydrophobicContact CG-CG2 4.45Å; L69-T73 WeakPolarHBondContact O-CB 3.4Å; L69-T73 WeakPolarHBondContact O-CG2 3.38Å; L69-T73 PolarHBondContact O-N 2.98Å; L69-T73 PolarHBondContact O-OG1 2.96Å; T73-K75 PolarHBondContact O-N 2.9Å; T73-K75 PolarHBondContact OG1-N 3.01Å; T73-K75 PolarHBondContact OG1-O 3.37Å; T73-V411 HydrophobicContact CG2-CG1 3.57Å
74	G	89.3	Confident	91.8	Very high	19 Å²	19	23 Å²	23	20%	0.196	11%	0.112	C	C	.	.	S	Bend	trans	69	2.7	-167.6	0	0	0	0	0	114.5	G70	G70-G74 WeakPolarHBondContact O-CA 3.23Å; G70-G74 PolarHBondContact O-N 3.23Å
75	K	91.1	Very high	91.6	Very high	78 Å²	78	18.4 Å²	18.4	34%	0.339	10%	0.095	S	C	.	.	S	Bend	trans	-116	143.6	-178	-65.4	-177.6	-179.2	179.6	0	110	G70 T73 E79 V80 L83	G70-K75 WeakPolarHBondContact CA-O 3.4Å; T73-K75 PolarHBondContact O-N 2.9Å; T73-K75 PolarHBondContact OG1-N 3.01Å; T73-K75 PolarHBondContact OG1-O 3.37Å; K75-E79 WeakPolarHBondContact CA-OE2 3.29Å; K75-E79 HydrophobicContact CB-CB 4.06Å; K75-E79 VanDerWaalsContact CB-OE2 3.31Å; K75-E79 WeakPolarHBondContact CB-OE2 3.49Å; K75-V80 HydrophobicContact CB-CG2 3.94Å; K75-L83 HydrophobicContact CD-CD1 3.78Å
76	D	92.8	Very high	91.3	Very high	4 Å²	4	21.3 Å²	21.3	2%	0.021	11%	0.114	C	C	.	.			trans	-76.7	166.3	174.4	59.1	70.3	0	0	0	111.2	G78 E79 V80 A218 K221	D76-G78 PolarHBondContact O-N 3.19Å; D76-G78 WeakPolarHBondContact OD1-CA 3.39Å; D76-G78 PolarHBondContact OD1-N 3.23Å; D76-E79 PolarHBondContact N-OE2 2.87Å; D76-E79 PolarHBondContact O-N 3.43Å; D76-E79 PolarHBondContact OD1-N 2.97Å; D76-E79 WeakPolarHBondContact OD2-CG 3.44Å; D76-V80 WeakPolarHBondContact O-CG2 3.41Å; D76-V80 PolarHBondContact O-N 3.44Å; D76-A218 HydrophobicContact CB-CB 3.81Å; D76-K221 HydrophobicContact CB-CD 4.16Å; D76-K221 IonicContact OD2-NZ 3.8Å; D76-K221 PolarHBondContact OD2-NZ 2.84Å
77	L	93.4	Very high	91	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-60.6	-29.9	-178.1	-177.9	61.9	0	0	0	112.2	L69 C81 I213 Y214 S217 P401 I402 F405	L69-L77 HydrophobicContact CD2-CB 4.21Å; L69-L77 HydrophobicContact CD2-CD1 3.58Å; L69-L77 HydrophobicContact CD2-CG 4.49Å; L77-C81 WeakPolarHBondContact O-CB 3.49Å; L77-C81 PolarHBondContact O-N 3.44Å; L77-C81 PolarHBondContact O-SG 3.27Å; L77-I213 HydrophobicContact CD2-CG2 3.98Å; L77-Y214 HydrophobicContact CB-CD1 3.76Å; L77-Y214 HydrophobicContact CB-CE1 3.88Å; L77-Y214 HydrophobicContact CD2-CD1 3.9Å; L77-Y214 HydrophobicContact CD2-CD2 4.41Å; L77-Y214 HydrophobicContact CD2-CE1 3.59Å; L77-Y214 HydrophobicContact CD2-CE2 4.14Å; L77-Y214 HydrophobicContact CD2-CG 4.29Å; L77-Y214 HydrophobicContact CG-CD1 3.88Å; L77-Y214 HydrophobicContact CG-CE1 3.48Å; L77-Y214 VanDerWaalsContact CG-CE1 3.48Å; L77-S217 WeakPolarHBondContact CB-OG 3.49Å; L77-S217 PolarHBondContact N-OG 3.44Å; L77-P401 HydrophobicContact CD1-CB 4.15Å; L77-I402 HydrophobicContact CD1-CB 4.31Å; L77-I402 HydrophobicContact CD1-CD1 4.13Å; L77-I402 HydrophobicContact CD2-CB 4.07Å; L77-F405 HydrophobicContact CD1-CD2 3.95Å
78	G	92.4	Very high	90.9	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-69.9	-46.5	176.4	0	0	0	0	0	112.2	D76 V80 C81 H82 G345	D76-G78 PolarHBondContact O-N 3.19Å; D76-G78 WeakPolarHBondContact OD1-CA 3.39Å; D76-G78 PolarHBondContact OD1-N 3.23Å; G78-V80 PolarHBondContact O-N 2.94Å; G78-C81 WeakPolarHBondContact O-CB 3.5Å; G78-C81 PolarHBondContact O-N 3.16Å; G78-H82 WeakPolarHBondContact O-CB 3.14Å; G78-H82 PolarHBondContact O-N 3.27Å; G78-G345 CarbonylContact O-C 3.53Å
79	E	92.9	Very high	90.7	Very high	62 Å²	62	32.5 Å²	32.5	29%	0.29	17%	0.172	S	C	.	.	H	α-helix	trans	-59	-42.9	172.7	-71.5	171.9	154.5	0	0	111.9	K75 D76 H82 L83 K221	K75-E79 WeakPolarHBondContact CA-OE2 3.29Å; K75-E79 HydrophobicContact CB-CB 4.06Å; K75-E79 VanDerWaalsContact CB-OE2 3.31Å; K75-E79 WeakPolarHBondContact CB-OE2 3.49Å; D76-E79 PolarHBondContact N-OE2 2.87Å; D76-E79 PolarHBondContact O-N 3.43Å; D76-E79 PolarHBondContact OD1-N 2.97Å; D76-E79 WeakPolarHBondContact OD2-CG 3.44Å; E79-H82 WeakPolarHBondContact O-CB 3.22Å; E79-H82 PolarHBondContact O-N 3.01Å; E79-L83 VanDerWaalsContact O-CG 3.29Å; E79-L83 WeakPolarHBondContact O-CG 3.38Å; E79-L83 PolarHBondContact O-N 3.11Å; E79-K221 IonicContact OE1-NZ 2.75Å; E79-K221 PolarHBondContact OE1-NZ 3.44Å; E79-K221 IonicContact OE2-NZ 3.22Å; E79-K221 PolarHBondContact OE2-NZ 2.96Å
80	V	92	Very high	90.6	Very high	5 Å²	5	34.5 Å²	34.5	3%	0.03	18%	0.18	C	C	.	.	H	α-helix	trans	-66.4	-43.1	176.2	178.9	0	0	0	0	111	L69 K75 D76 G78 H82 L83 Y84 F405	L69-V80 HydrophobicContact CD2-CG2 4.38Å; K75-V80 HydrophobicContact CB-CG2 3.94Å; D76-V80 WeakPolarHBondContact O-CG2 3.41Å; D76-V80 PolarHBondContact O-N 3.44Å; G78-V80 PolarHBondContact O-N 2.94Å; V80-H82 VanDerWaalsContact C-N 3.27Å; V80-H82 PolarHBondContact O-N 3.12Å; V80-L83 PolarHBondContact O-N 3.15Å; V80-Y84 HydrophobicContact CG1-CD2 4.01Å; V80-Y84 HydrophobicContact CG1-CE2 4.38Å; V80-Y84 PolarHBondContact O-N 3.11Å; V80-Y84 VanDerWaalsContact O-N 3.15Å; V80-F405 HydrophobicContact CG1-CB 4.26Å; V80-F405 HydrophobicContact CG1-CD1 3.78Å; V80-F405 HydrophobicContact CG1-CD2 3.67Å; V80-F405 HydrophobicContact CG1-CE1 4.02Å; V80-F405 HydrophobicContact CG1-CE2 3.91Å; V80-F405 HydrophobicContact CG1-CG 3.62Å; V80-F405 HydrophobicContact CG1-CZ 4.08Å
81	C	91.5	Very high	90.6	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	20%	0.198	C	C	.	.	H	α-helix	trans	-58.1	-39.5	172.5	-73	0	0	0	0	111.9	L77 G78 L83 Y85 L93 F346	L77-C81 WeakPolarHBondContact O-CB 3.49Å; L77-C81 PolarHBondContact O-N 3.44Å; L77-C81 PolarHBondContact O-SG 3.27Å; G78-C81 WeakPolarHBondContact O-CB 3.5Å; G78-C81 PolarHBondContact O-N 3.16Å; C81-L83 VanDerWaalsContact C-N 3.3Å; C81-L83 PolarHBondContact O-N 3.34Å; C81-Y85 HydrophobicContact CB-CD2 3.98Å; C81-Y85 HydrophobicContact CB-CE2 4.44Å; C81-Y85 WeakPolarHBondContact O-CB 3.14Å; C81-Y85 PolarHBondContact O-N 2.64Å; C81-L93 HydrophobicContact CB-CD2 4.4Å; C81-F346 HydrophobicContact CB-CD1 4.25Å; C81-F346 HydrophobicContact CB-CE1 3.48Å; C81-F346 VanDerWaalsContact CB-CE1 3.48Å; C81-F346 HydrophobicContact CB-CZ 3.72Å
82	H	90.2	Very high	90.6	Very high	28 Å²	28	41.8 Å²	41.8	13%	0.13	22%	0.217	C	C	.	.	H	α-helix	trans	-64.1	-34.6	179.1	177.4	110	0	0	0	113.7	G78 E79 V80 R90 G345 F346 K348	G78-H82 WeakPolarHBondContact O-CB 3.14Å; G78-H82 PolarHBondContact O-N 3.27Å; E79-H82 WeakPolarHBondContact O-CB 3.22Å; E79-H82 PolarHBondContact O-N 3.01Å; V80-H82 VanDerWaalsContact C-N 3.27Å; V80-H82 PolarHBondContact O-N 3.12Å; H82-R90 PolarHBondContact CE1-NH1 3.01Å; H82-R90 VanDerWaalsContact CE1-NH1 3.34Å; H82-R90 PolarHBondContact ND1-NH1 2.59Å; H82-R90 PolarHBondContact O-NH1 3.25Å; H82-G345 VanDerWaalsContact CB-O 3.22Å; H82-G345 WeakPolarHBondContact CB-O 2.98Å; H82-F346 PolarHBondContact ND1-O 3.36Å; H82-K348 VanDerWaalsContact NE2-CE 3.26Å; H82-K348 WeakPolarHBondContact NE2-CE 3.25Å; H82-K348 PolarHBondContact NE2-NZ 3.41Å
83	L	88.3	Confident	90.7	Very high	39 Å²	39	40.7 Å²	40.7	20%	0.204	21%	0.211	C	C	.	.	H	α-helix	trans	-79.7	-35	-177.2	-72.1	169.9	0	0	0	113.2	K75 E79 V80 C81 L495	K75-L83 HydrophobicContact CD-CD1 3.78Å; E79-L83 VanDerWaalsContact O-CG 3.29Å; E79-L83 WeakPolarHBondContact O-CG 3.38Å; E79-L83 PolarHBondContact O-N 3.11Å; V80-L83 PolarHBondContact O-N 3.15Å; C81-L83 VanDerWaalsContact C-N 3.3Å; C81-L83 PolarHBondContact O-N 3.34Å; L83-L495 HydrophobicContact CB-CD1 4.19Å; L83-L495 HydrophobicContact CD1-CD1 4.49Å; L83-L495 HydrophobicContact CD2-CD1 4.03Å; L83-L495 HydrophobicContact CG-CD1 4.46Å
84	Y	86.5	Confident	90.9	Very high	31 Å²	31	41.4 Å²	41.4	12%	0.122	21%	0.209	C	C	.	.	H	α-helix	trans	-102.2	-29.1	-173.6	-78.5	-91.7	0	0	0	114.8	V80 F405 M408 V411 F491	V80-Y84 HydrophobicContact CG1-CD2 4.01Å; V80-Y84 HydrophobicContact CG1-CE2 4.38Å; V80-Y84 PolarHBondContact O-N 3.11Å; V80-Y84 VanDerWaalsContact O-N 3.15Å; Y84-F405 HydrophobicContact CD1-CE1 4.3Å; Y84-F405 HydrophobicContact CD2-CE1 4.01Å; Y84-F405 AromaticContact CG-CE1 3.7Å; Y84-F405 HydrophobicContact CG-CE1 3.7Å; Y84-F405 HydrophobicContact CG-CZ 4.34Å; Y84-M408 HydrophobicContact CD1-CE 4.16Å; Y84-M408 HydrophobicContact CE1-CE 3.97Å; Y84-V411 HydrophobicContact CE1-CG2 4.29Å; Y84-V411 HydrophobicContact CE2-CG2 3.84Å; Y84-F491 HydrophobicContact CD1-CD2 4.3Å; Y84-F491 HydrophobicContact CD1-CE2 4.42Å
85	Y	88	Confident	91.1	Very high	6 Å²	6	44.6 Å²	44.6	2%	0.024	22%	0.222	C	C	.	.	S	Bend	trans	-92.3	139.4	-179.7	-69.1	-58.4	0	0	0	112.9	C81 L93 P401 F405 Y469 L470 T473 F491	C81-Y85 HydrophobicContact CB-CD2 3.98Å; C81-Y85 HydrophobicContact CB-CE2 4.44Å; C81-Y85 WeakPolarHBondContact O-CB 3.14Å; C81-Y85 PolarHBondContact O-N 2.64Å; Y85-L93 HydrophobicContact CD2-CD2 4.25Å; Y85-L93 HydrophobicContact CE2-CD2 4.23Å; Y85-P401 HydrophobicContact CE2-CB 4.25Å; Y85-P401 HydrophobicContact CE2-CG 4.27Å; Y85-F405 HydrophobicContact CD2-CZ 4.19Å; Y85-F405 AromaticContact CE2-CE2 3.8Å; Y85-F405 HydrophobicContact CE2-CE2 3.8Å; Y85-F405 AromaticContact CE2-CZ 3.66Å; Y85-F405 HydrophobicContact CE2-CZ 3.66Å; Y85-Y469 AromaticContact CD1-CE1 3.84Å; Y85-Y469 HydrophobicContact CD1-CE1 3.84Å; Y85-Y469 AromaticContact CE1-CE1 3.98Å; Y85-Y469 HydrophobicContact CE1-CE1 3.98Å; Y85-L470 HydrophobicContact CE1-CD2 3.79Å; Y85-L470 HydrophobicContact CE2-CD2 4.07Å; Y85-L470 VanDerWaalsContact CZ-CD2 3.5Å; Y85-L470 WeakPolarHBondContact OH-CD2 3.38Å; Y85-T473 HydrophobicContact CE1-CG2 4.27Å; Y85-T473 PolarHBondContact OH-OG1 2.87Å; Y85-F491 HydrophobicContact CD1-CE2 4.32Å; Y85-F491 HydrophobicContact CE1-CE2 4.1Å; Y85-F491 HydrophobicContact CE1-CZ 4.23Å
86	P	88.1	Confident	91.1	Very high	68 Å²	68	42 Å²	42	44%	0.442	21%	0.212	S	C	.	.			trans	-67.7	161.7	175.9	26.5	-30.2	0	0	0	111.8	V88 P89 R90 Y469	P86-V88 VanDerWaalsContact C-N 3.29Å; P86-V88 PolarHBondContact O-N 3.39Å; P86-V88 VanDerWaalsContact O-N 3.08Å; P86-P89 HydrophobicContact CG-CG 4.05Å; P86-P89 WeakPolarHBondContact O-CD 3.47Å; P86-R90 VanDerWaalsContact O-CB 3.3Å; P86-R90 WeakPolarHBondContact O-CB 3.38Å; P86-R90 PolarHBondContact O-N 2.91Å; P86-Y469 WeakPolarHBondContact CD-OH 3.3Å
87	K	87.8	Confident	91.2	Very high	156 Å²	156	41.8 Å²	41.8	68%	0.678	21%	0.211	S	C	*	.	H	α-helix	trans	-49.3	-42.3	-168.8	-65.4	-176.9	-179	178.9	0	114.5	I91	K87-I91 WeakPolarHBondContact O-CD1 3.44Å; K87-I91 VanDerWaalsContact O-CG1 3.25Å; K87-I91 WeakPolarHBondContact O-CG1 3.28Å; K87-I91 PolarHBondContact O-N 3.39Å; K87-I91 VanDerWaalsContact O-N 3.08Å
88	V	90.2	Very high	91.1	Very high	104 Å²	104	42.8 Å²	42.8	63%	0.63	22%	0.216	S	C	*	.	H	α-helix	trans	-71.6	-59.8	-174.8	174.1	0	0	0	0	112.3	P86 R90 I91 L92	P86-V88 VanDerWaalsContact C-N 3.29Å; P86-V88 PolarHBondContact O-N 3.39Å; P86-V88 VanDerWaalsContact O-N 3.08Å; V88-R90 PolarHBondContact O-N 3.42Å; V88-I91 PolarHBondContact O-N 3.43Å; V88-I91 VanDerWaalsContact O-N 3.16Å; V88-L92 HydrophobicContact CG1-CD1 4.15Å; V88-L92 WeakPolarHBondContact O-CG 3.32Å; V88-L92 PolarHBondContact O-N 2.69Å
89	P	90.1	Very high	91.1	Very high	21 Å²	21	46.9 Å²	46.9	14%	0.136	24%	0.237	C	C	.	.	H	α-helix	trans	-53.9	-36.8	172.9	-28.2	35	0	0	0	113.6	P86 L92 L93 L466 Y469	P86-P89 HydrophobicContact CG-CG 4.05Å; P86-P89 WeakPolarHBondContact O-CD 3.47Å; P89-L92 PolarHBondContact O-N 2.94Å; P89-L93 WeakPolarHBondContact O-CB 3.29Å; P89-L93 PolarHBondContact O-N 3.43Å; P89-L466 HydrophobicContact CB-CD1 4.2Å; P89-Y469 HydrophobicContact CB-CD1 4.09Å; P89-Y469 HydrophobicContact CB-CE1 3.68Å; P89-Y469 HydrophobicContact CG-CD1 4.14Å; P89-Y469 HydrophobicContact CG-CE1 3.71Å
90	R	91.4	Very high	91.1	Very high	43 Å²	43	44 Å²	44	16%	0.162	22%	0.224	C	C	.	.	H	α-helix	trans	-61.8	-44.8	177.4	-176.6	-177.8	70.4	-172.9	12.6	113.1	H82 P86 V88 W94 F346	H82-R90 PolarHBondContact CE1-NH1 3.01Å; H82-R90 VanDerWaalsContact CE1-NH1 3.34Å; H82-R90 PolarHBondContact ND1-NH1 2.59Å; H82-R90 PolarHBondContact O-NH1 3.25Å; P86-R90 VanDerWaalsContact O-CB 3.3Å; P86-R90 WeakPolarHBondContact O-CB 3.38Å; P86-R90 PolarHBondContact O-N 2.91Å; V88-R90 PolarHBondContact O-N 3.42Å; R90-W94 PolarHBondContact O-N 3.01Å; R90-F346 HydrophobicContact CG-CD1 3.89Å
91	I	92.3	Very high	91.1	Very high	75 Å²	75	43.8 Å²	43.8	39%	0.385	22%	0.222	S	C	.	.	H	α-helix	trans	-71.7	-39.2	179.7	-69.2	165.5	0	0	0	110.7	K87 V88 W94 L95	K87-I91 WeakPolarHBondContact O-CD1 3.44Å; K87-I91 VanDerWaalsContact O-CG1 3.25Å; K87-I91 WeakPolarHBondContact O-CG1 3.28Å; K87-I91 PolarHBondContact O-N 3.39Å; K87-I91 VanDerWaalsContact O-N 3.08Å; V88-I91 PolarHBondContact O-N 3.43Å; V88-I91 VanDerWaalsContact O-N 3.16Å; I91-W94 PolarHBondContact O-N 3.27Å; I91-L95 HydrophobicContact CG2-CD1 4.37Å; I91-L95 WeakPolarHBondContact O-CG 3.2Å; I91-L95 PolarHBondContact O-N 3.17Å
92	L	93.2	Very high	91.1	Very high	79 Å²	79	45.1 Å²	45.1	41%	0.414	23%	0.23	S	C	.	.	H	α-helix	trans	-63.5	-42.1	174.7	-65.1	175.4	0	0	0	111.7	V88 P89 L95 T96 L466	V88-L92 HydrophobicContact CG1-CD1 4.15Å; V88-L92 WeakPolarHBondContact O-CG 3.32Å; V88-L92 PolarHBondContact O-N 2.69Å; P89-L92 PolarHBondContact O-N 2.94Å; L92-L95 PolarHBondContact O-N 3.23Å; L92-T96 WeakPolarHBondContact O-CG2 3.22Å; L92-T96 PolarHBondContact O-N 3.41Å; L92-T96 PolarHBondContact O-OG1 2.81Å; L92-L466 HydrophobicContact CB-CD1 4.49Å; L92-L466 HydrophobicContact CB-CD2 3.86Å
93	L	92.7	Very high	91.1	Very high	1 Å²	1	43.9 Å²	43.9	1%	0.005	23%	0.225	C	C	.	.	H	α-helix	trans	-65.6	-37.7	175.9	177.8	55	0	0	0	112.2	C81 Y85 P89 T96 I97 F346 F397 P401	C81-L93 HydrophobicContact CB-CD2 4.4Å; Y85-L93 HydrophobicContact CD2-CD2 4.25Å; Y85-L93 HydrophobicContact CE2-CD2 4.23Å; P89-L93 WeakPolarHBondContact O-CB 3.29Å; P89-L93 PolarHBondContact O-N 3.43Å; L93-T96 PolarHBondContact O-OG1 2.77Å; L93-T96 VanDerWaalsContact O-OG1 3.06Å; L93-I97 HydrophobicContact CD1-CG1 4.21Å; L93-I97 WeakPolarHBondContact O-CG1 3.06Å; L93-I97 PolarHBondContact O-N 3.03Å; L93-F346 HydrophobicContact CB-CE1 4.08Å; L93-F346 HydrophobicContact CD2-CE1 3.7Å; L93-F346 HydrophobicContact CD2-CZ 3.86Å; L93-F346 HydrophobicContact CG-CE1 3.58Å; L93-F346 HydrophobicContact CG-CZ 3.67Å; L93-F397 HydrophobicContact CD1-CB 3.62Å; L93-F397 HydrophobicContact CD1-CG 4.46Å; L93-F397 VanDerWaalsContact CD1-O 3.25Å; L93-F397 WeakPolarHBondContact CD1-O 3.09Å; L93-P401 HydrophobicContact CD2-CG 4Å
94	W	94.1	Very high	91.2	Very high	50 Å²	50	42.1 Å²	42.1	19%	0.189	22%	0.216	C	C	.	.	H	α-helix	trans	-61.3	-49.1	170.9	170.9	68	0	0	0	111.5	R90 I91 T96 I97 E98 F346 L347	R90-W94 PolarHBondContact O-N 3.01Å; I91-W94 PolarHBondContact O-N 3.27Å; W94-T96 VanDerWaalsContact C-N 3.33Å; W94-T96 PolarHBondContact O-N 2.96Å; W94-I97 PolarHBondContact O-N 3.41Å; W94-E98 HydrophobicContact CD2-CG 4.15Å; W94-E98 VanDerWaalsContact CE2-CG 3.44Å; W94-E98 HydrophobicContact CG-CG 4.41Å; W94-E98 HydrophobicContact CZ2-CG 3.69Å; W94-E98 VanDerWaalsContact NE1-CG 3.26Å; W94-E98 PolarHBondContact NE1-OE1 3.39Å; W94-E98 WeakPolarHBondContact O-CG 3.25Å; W94-E98 PolarHBondContact O-N 3.23Å; W94-F346 HydrophobicContact CB-CB 3.86Å; W94-F346 HydrophobicContact CB-CD1 4Å; W94-F346 HydrophobicContact CB-CG 3.91Å; W94-F346 HydrophobicContact CG-CB 4.04Å; W94-F346 HydrophobicContact CG-CG 4.44Å; W94-L347 HydrophobicContact CD2-CD1 3.6Å; W94-L347 HydrophobicContact CD2-CD2 4.28Å; W94-L347 HydrophobicContact CD2-CG 3.98Å; W94-L347 VanDerWaalsContact CE2-CD1 3.44Å; W94-L347 HydrophobicContact CE3-CD1 3.89Å; W94-L347 HydrophobicContact CE3-CD2 4.44Å; W94-L347 HydrophobicContact CE3-CG 4.49Å; W94-L347 HydrophobicContact CG-CD1 4.22Å; W94-L347 HydrophobicContact CG-CD2 4.35Å; W94-L347 HydrophobicContact CG-CG 4.09Å; W94-L347 HydrophobicContact CH2-CD1 3.93Å; W94-L347 HydrophobicContact CZ2-CD1 3.63Å; W94-L347 HydrophobicContact CZ3-CD1 4.04Å
95	L	93.3	Very high	91.4	Very high	87 Å²	87	40.7 Å²	40.7	46%	0.455	21%	0.211	S	C	.	.	H	α-helix	trans	-58.7	-39.6	178.7	-75.3	170.3	0	0	0	113.1	I91 L92 L99	I91-L95 HydrophobicContact CG2-CD1 4.37Å; I91-L95 WeakPolarHBondContact O-CG 3.2Å; I91-L95 PolarHBondContact O-N 3.17Å; L92-L95 PolarHBondContact O-N 3.23Å; L95-L99 WeakPolarHBondContact O-CB 3.42Å; L95-L99 PolarHBondContact O-N 3.15Å
96	T	92.9	Very high	91.4	Very high	23 Å²	23	41.4 Å²	41.4	14%	0.141	22%	0.215	C	C	.	.	H	α-helix	trans	-70.6	-31.9	178.9	53.1	0	0	0	0	112.8	L92 L93 W94 A100 L394 F397	L92-T96 WeakPolarHBondContact O-CG2 3.22Å; L92-T96 PolarHBondContact O-N 3.41Å; L92-T96 PolarHBondContact O-OG1 2.81Å; L93-T96 PolarHBondContact O-OG1 2.77Å; L93-T96 VanDerWaalsContact O-OG1 3.06Å; W94-T96 VanDerWaalsContact C-N 3.33Å; W94-T96 PolarHBondContact O-N 2.96Å; T96-A100 PolarHBondContact O-N 2.92Å; T96-A100 VanDerWaalsContact O-N 3.12Å; T96-L394 HydrophobicContact CG2-CD2 4.19Å; T96-F397 HydrophobicContact CG2-CD2 3.75Å; T96-F397 HydrophobicContact CG2-CE2 3.68Å; T96-F397 HydrophobicContact CG2-CG 4.4Å; T96-F397 HydrophobicContact CG2-CZ 4.32Å
97	I	93.2	Very high	91.4	Very high	0 Å²	0	39.3 Å²	39.3	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-79	-36.8	176	-58.6	-58	0	0	0	111.9	L93 W94 L99 A100 I101 P210 Y214 V342 F397 A398	L93-I97 HydrophobicContact CD1-CG1 4.21Å; L93-I97 WeakPolarHBondContact O-CG1 3.06Å; L93-I97 PolarHBondContact O-N 3.03Å; W94-I97 PolarHBondContact O-N 3.41Å; I97-L99 VanDerWaalsContact C-N 3.3Å; I97-L99 PolarHBondContact O-N 2.98Å; I97-A100 WeakPolarHBondContact O-CB 3.16Å; I97-A100 PolarHBondContact O-N 3.49Å; I97-A100 VanDerWaalsContact O-N 3.15Å; I97-I101 HydrophobicContact CG2-CD1 4.2Å; I97-I101 WeakPolarHBondContact O-CD1 3.28Å; I97-I101 WeakPolarHBondContact O-CG1 3.22Å; I97-I101 PolarHBondContact O-N 3.03Å; I97-P210 HydrophobicContact CD1-CB 4.18Å; I97-Y214 HydrophobicContact CD1-CD2 4.25Å; I97-Y214 HydrophobicContact CD1-CE2 3.53Å; I97-Y214 HydrophobicContact CG1-CD2 4.31Å; I97-Y214 HydrophobicContact CG1-CE2 3.62Å; I97-Y214 HydrophobicContact CG2-CD2 3.95Å; I97-Y214 HydrophobicContact CG2-CE2 4.12Å; I97-V342 HydrophobicContact CB-CG1 4.23Å; I97-V342 HydrophobicContact CG2-CB 4.41Å; I97-V342 HydrophobicContact CG2-CG1 3.9Å; I97-V342 HydrophobicContact CG2-CG2 3.63Å; I97-F397 HydrophobicContact CD1-CB 4.21Å; I97-A398 HydrophobicContact CD1-CB 4.17Å
98	E	92.3	Very high	91.5	Very high	21 Å²	21	32.3 Å²	32.3	10%	0.098	17%	0.169	C	C	.	.	H	α-helix	trans	-60.9	-40.1	169.5	-67	-64.7	167.9	0	0	111.6	W94 A100 I101 V102 M343	W94-E98 HydrophobicContact CD2-CG 4.15Å; W94-E98 VanDerWaalsContact CE2-CG 3.44Å; W94-E98 HydrophobicContact CG-CG 4.41Å; W94-E98 HydrophobicContact CZ2-CG 3.69Å; W94-E98 VanDerWaalsContact NE1-CG 3.26Å; W94-E98 PolarHBondContact NE1-OE1 3.39Å; W94-E98 WeakPolarHBondContact O-CG 3.25Å; W94-E98 PolarHBondContact O-N 3.23Å; E98-A100 VanDerWaalsContact C-N 3.3Å; E98-A100 PolarHBondContact O-N 3.02Å; E98-I101 PolarHBondContact O-N 2.86Å; E98-V102 WeakPolarHBondContact O-CG2 3.4Å; E98-V102 PolarHBondContact O-N 3.25Å; E98-M343 WeakPolarHBondContact OE1-CG 3.5Å
99	L	92.3	Very high	91.5	Very high	86 Å²	86	27.3 Å²	27.3	45%	0.45	14%	0.139	S	C	.	.	H	α-helix	trans	-62.2	-37.3	173.7	-176.8	62.7	0	0	0	112	L95 I97 G103 L390 L394	L95-L99 WeakPolarHBondContact O-CB 3.42Å; L95-L99 PolarHBondContact O-N 3.15Å; I97-L99 VanDerWaalsContact C-N 3.3Å; I97-L99 PolarHBondContact O-N 2.98Å; L99-G103 PolarHBondContact O-N 2.95Å; L99-L390 HydrophobicContact CD2-CD1 4.31Å; L99-L390 HydrophobicContact CG-CD2 4.37Å; L99-L394 HydrophobicContact CB-CD1 4.31Å; L99-L394 HydrophobicContact CD2-CD1 4.31Å; L99-L394 HydrophobicContact CD2-CD2 4.4Å; L99-L394 HydrophobicContact CG-CD1 4.11Å
100	A	92.7	Very high	91.4	Very high	0 Å²	0	26.6 Å²	26.6	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-66.2	-37.8	173.7	0	0	0	0	0	112.1	T96 I97 E98 S104 P210 Q391 L394	T96-A100 PolarHBondContact O-N 2.92Å; T96-A100 VanDerWaalsContact O-N 3.12Å; I97-A100 WeakPolarHBondContact O-CB 3.16Å; I97-A100 PolarHBondContact O-N 3.49Å; I97-A100 VanDerWaalsContact O-N 3.15Å; E98-A100 VanDerWaalsContact C-N 3.3Å; E98-A100 PolarHBondContact O-N 3.02Å; A100-S104 PolarHBondContact O-N 2.88Å; A100-S104 VanDerWaalsContact O-N 3.08Å; A100-P210 HydrophobicContact CB-CB 4.24Å; A100-P210 HydrophobicContact CB-CG 4.24Å; A100-Q391 PolarHBondContact O-NE2 3.28Å; A100-Q391 PolarHBondContact O-OE1 3.06Å; A100-L394 HydrophobicContact CB-CB 4.33Å; A100-L394 HydrophobicContact CB-CD1 3.74Å
101	I	91.7	Very high	91.3	Very high	1 Å²	1	24.8 Å²	24.8	1%	0.005	13%	0.128	C	C	.	.	H	α-helix	trans	-66.5	-53	176.2	-66.8	156.2	0	0	0	110.2	I97 E98 G103 S104 D105 H211 G335 A338 V342	I97-I101 HydrophobicContact CG2-CD1 4.2Å; I97-I101 WeakPolarHBondContact O-CD1 3.28Å; I97-I101 WeakPolarHBondContact O-CG1 3.22Å; I97-I101 PolarHBondContact O-N 3.03Å; E98-I101 PolarHBondContact O-N 2.86Å; I101-G103 VanDerWaalsContact C-N 3.27Å; I101-G103 PolarHBondContact O-N 3.04Å; I101-S104 WeakPolarHBondContact O-CB 3.22Å; I101-S104 PolarHBondContact O-N 3.07Å; I101-S104 VanDerWaalsContact O-N 3.09Å; I101-D105 WeakPolarHBondContact O-CB 3.3Å; I101-D105 PolarHBondContact O-N 3.45Å; I101-H211 HydrophobicContact CD1-CB 4.4Å; I101-H211 HydrophobicContact CG1-CB 3.59Å; I101-G335 WeakPolarHBondContact CG2-O 3.41Å; I101-A338 HydrophobicContact CD1-CB 4.44Å; I101-A338 HydrophobicContact CG1-CB 4.39Å; I101-V342 HydrophobicContact CD1-CB 4.27Å; I101-V342 HydrophobicContact CD1-CG1 4.43Å; I101-V342 HydrophobicContact CD1-CG2 4.23Å
102	V	91.1	Very high	91.2	Very high	28 Å²	28	21.2 Å²	21.2	17%	0.17	11%	0.11	C	C	.	.	H	α-helix	trans	-60.2	-37.4	177.7	174.3	0	0	0	0	111.3	E98 S104 D105 M106 C363 A364	E98-V102 WeakPolarHBondContact O-CG2 3.4Å; E98-V102 PolarHBondContact O-N 3.25Å; V102-S104 PolarHBondContact O-N 2.71Å; V102-D105 WeakPolarHBondContact O-CB 3.39Å; V102-D105 PolarHBondContact O-N 3.08Å; V102-M106 WeakPolarHBondContact O-CG 3.4Å; V102-M106 PolarHBondContact O-N 2.98Å; V102-C363 HydrophobicContact CG1-CB 4.24Å; V102-C363 HydrophobicContact CG2-CB 4.31Å; V102-A364 HydrophobicContact CG1-CB 4.31Å
103	G	90.8	Very high	91.1	Very high	2 Å²	2	17.6 Å²	17.6	2%	0.021	9%	0.091	C	C	.	.	H	α-helix	trans	-62.9	-40.9	174.8	0	0	0	0	0	113	L99 I101 M106 Q107	L99-G103 PolarHBondContact O-N 2.95Å; I101-G103 VanDerWaalsContact C-N 3.27Å; I101-G103 PolarHBondContact O-N 3.04Å; G103-M106 PolarHBondContact O-N 3.06Å; G103-Q107 WeakPolarHBondContact O-CG 3.38Å; G103-Q107 PolarHBondContact O-N 3.29Å
104	S	90.3	Very high	91	Very high	2 Å²	2	17.7 Å²	17.7	1%	0.014	9%	0.092	C	C	.	.	H	α-helix	trans	-70.5	-38.1	176.9	-167.4	0	0	0	0	112.4	A100 I101 V102 M106 Q107 E108 M209 H211 Q391	A100-S104 PolarHBondContact O-N 2.88Å; A100-S104 VanDerWaalsContact O-N 3.08Å; I101-S104 WeakPolarHBondContact O-CB 3.22Å; I101-S104 PolarHBondContact O-N 3.07Å; I101-S104 VanDerWaalsContact O-N 3.09Å; V102-S104 PolarHBondContact O-N 2.71Å; S104-M106 VanDerWaalsContact C-N 3.32Å; S104-M106 PolarHBondContact O-N 3.19Å; S104-Q107 PolarHBondContact O-N 3.17Å; S104-E108 WeakPolarHBondContact O-CB 3.28Å; S104-E108 PolarHBondContact O-N 3.01Å; S104-E108 VanDerWaalsContact O-N 3.14Å; S104-M209 WeakPolarHBondContact OG-CE 3.2Å; S104-H211 VanDerWaalsContact CB-CE1 3.49Å; S104-H211 WeakPolarHBondContact CB-CE1 3.48Å; S104-H211 PolarHBondContact OG-CE1 3.07Å; S104-Q391 VanDerWaalsContact N-NE2 3.2Å
105	D	90.3	Very high	90.9	Very high	2 Å²	2	15.3 Å²	15.3	1%	0.011	8%	0.083	C	C	.	.	H	α-helix	trans	-57.4	-44.3	173.9	-165.9	-44.3	0	0	0	110.5	I101 V102 E108 V109 R361 A364	I101-D105 WeakPolarHBondContact O-CB 3.3Å; I101-D105 PolarHBondContact O-N 3.45Å; V102-D105 WeakPolarHBondContact O-CB 3.39Å; V102-D105 PolarHBondContact O-N 3.08Å; D105-E108 PolarHBondContact O-N 3.24Å; D105-V109 WeakPolarHBondContact O-CG2 3.03Å; D105-V109 PolarHBondContact O-N 3.22Å; D105-R361 IonicContact OD1-CZ 3.2Å; D105-R361 IonicContact OD1-NE 3.71Å; D105-R361 PolarHBondContact OD1-NE 2.89Å; D105-R361 IonicContact OD1-NH1 3.16Å; D105-R361 IonicContact OD1-NH2 3.67Å; D105-R361 PolarHBondContact OD1-NH2 2.91Å; D105-R361 VanDerWaalsContact OD1-NH2 3.13Å; D105-R361 IonicContact OD2-CZ 3.96Å; D105-R361 IonicContact OD2-NE 2.73Å; D105-R361 PolarHBondContact OD2-NE 3.48Å; D105-R361 IonicContact OD2-NH2 2.7Å; D105-R361 PolarHBondContact OD2-NH2 3.35Å; D105-A364 HydrophobicContact CB-CB 3.68Å; D105-A364 WeakPolarHBondContact OD1-CB 3.43Å
106	M	89.2	Confident	90.9	Very high	21 Å²	21	13.7 Å²	13.7	10%	0.103	7%	0.072	C	C	.	.	H	α-helix	trans	-61.4	-45.4	174.1	-71.3	176.7	65.5	0	0	113.3	V102 G103 S104 E108 V109 I110 A364 P367 L383 L387	V102-M106 WeakPolarHBondContact O-CG 3.4Å; V102-M106 PolarHBondContact O-N 2.98Å; G103-M106 PolarHBondContact O-N 3.06Å; S104-M106 VanDerWaalsContact C-N 3.32Å; S104-M106 PolarHBondContact O-N 3.19Å; M106-E108 VanDerWaalsContact C-N 3.26Å; M106-E108 PolarHBondContact O-N 3.45Å; M106-V109 PolarHBondContact O-N 3.19Å; M106-I110 WeakPolarHBondContact O-CD1 3.45Å; M106-I110 WeakPolarHBondContact O-CG1 3.49Å; M106-I110 PolarHBondContact O-N 3.23Å; M106-A364 HydrophobicContact CG-CB 3.72Å; M106-P367 HydrophobicContact CE-CB 4.02Å; M106-P367 HydrophobicContact CE-CG 3.79Å; M106-P367 HydrophobicContact SD-CG 3.84Å; M106-L383 HydrophobicContact CE-CD1 4.21Å; M106-L383 HydrophobicContact CE-CD2 3.88Å; M106-L383 HydrophobicContact CE-CG 4.38Å; M106-L387 HydrophobicContact CB-CD1 3.63Å; M106-L387 HydrophobicContact CE-CD1 4.34Å; M106-L387 HydrophobicContact SD-CD2 4.4Å
107	Q	88.7	Confident	90.7	Very high	24 Å²	24	13.1 Å²	13.1	11%	0.112	7%	0.068	C	C	.	.	H	α-helix	trans	-60.2	-39.8	179.2	-64.1	-178.4	-67.8	0	0	111.9	G103 S104 I110 G111 N384 L387 N388	G103-Q107 WeakPolarHBondContact O-CG 3.38Å; G103-Q107 PolarHBondContact O-N 3.29Å; S104-Q107 PolarHBondContact O-N 3.17Å; Q107-I110 PolarHBondContact O-N 3.3Å; Q107-G111 PolarHBondContact O-N 3.34Å; Q107-N384 WeakPolarHBondContact CG-OD1 3.19Å; Q107-N384 PolarHBondContact NE2-O 3.46Å; Q107-N384 PolarHBondContact NE2-OD1 2.91Å; Q107-N384 VanDerWaalsContact NE2-OD1 3.16Å; Q107-L387 HydrophobicContact CG-CB 3.51Å; Q107-L387 HydrophobicContact CG-CD1 3.64Å; Q107-L387 HydrophobicContact CG-CG 4.2Å; Q107-N388 PolarHBondContact NE2-OD1 3.04Å
108	E	89.1	Confident	90.6	Very high	8 Å²	8	13.1 Å²	13.1	4%	0.037	7%	0.068	C	C	.	.	H	α-helix	trans	-70.4	-41.7	179	173.8	-124.8	119.8	0	0	112.7	S104 D105 M106 I110 G111 T112 G328 T332 R361	S104-E108 WeakPolarHBondContact O-CB 3.28Å; S104-E108 PolarHBondContact O-N 3.01Å; S104-E108 VanDerWaalsContact O-N 3.14Å; D105-E108 PolarHBondContact O-N 3.24Å; M106-E108 VanDerWaalsContact C-N 3.26Å; M106-E108 PolarHBondContact O-N 3.45Å; E108-I110 VanDerWaalsContact C-N 3.31Å; E108-I110 PolarHBondContact O-N 2.98Å; E108-G111 PolarHBondContact O-N 3.43Å; E108-T112 VanDerWaalsContact O-CB 3.31Å; E108-T112 WeakPolarHBondContact O-CB 3.33Å; E108-T112 PolarHBondContact O-N 2.93Å; E108-T112 PolarHBondContact O-OG1 3.33Å; E108-G328 WeakPolarHBondContact CG-O 3.36Å; E108-T332 VanDerWaalsContact CD-CB 3.44Å; E108-T332 WeakPolarHBondContact OE1-CB 3.24Å; E108-T332 WeakPolarHBondContact OE2-CA 3.45Å; E108-T332 VanDerWaalsContact OE2-CB 3.26Å; E108-T332 WeakPolarHBondContact OE2-CB 3.46Å; E108-T332 PolarHBondContact OE2-N 2.99Å; E108-R361 VanDerWaalsContact CD-NH1 3.31Å; E108-R361 IonicContact OE1-CZ 2.9Å; E108-R361 IonicContact OE1-NH1 3.32Å; E108-R361 PolarHBondContact OE1-NH1 2.97Å; E108-R361 IonicContact OE1-NH2 2.99Å; E108-R361 IonicContact OE2-CZ 3.98Å; E108-R361 IonicContact OE2-NH1 3.12Å; E108-R361 PolarHBondContact OE2-NH1 2.85Å; E108-R361 VanDerWaalsContact OE2-NH1 3.16Å; E108-R361 IonicContact OE2-NH2 2.83Å; E108-R361 PolarHBondContact OE2-NH2 3.48Å
109	V	89.4	Confident	90.6	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-62.3	-40.2	172.7	170	0	0	0	0	110.9	D105 M106 A113 V130 T133 I365 T368	D105-V109 WeakPolarHBondContact O-CG2 3.03Å; D105-V109 PolarHBondContact O-N 3.22Å; M106-V109 PolarHBondContact O-N 3.19Å; V109-A113 VanDerWaalsContact O-CB 3.31Å; V109-A113 WeakPolarHBondContact O-CB 3.43Å; V109-A113 PolarHBondContact O-N 3.4Å; V109-V130 HydrophobicContact CG1-CB 4.29Å; V109-V130 HydrophobicContact CG1-CG1 3.73Å; V109-V130 HydrophobicContact CG1-CG2 4.11Å; V109-T133 HydrophobicContact CG1-CG2 4.2Å; V109-I365 HydrophobicContact CG1-CG1 4.33Å; V109-I365 HydrophobicContact CG2-CG1 4.07Å; V109-T368 HydrophobicContact CG1-CG2 4.05Å
110	I	88.4	Confident	90.5	Very high	6 Å²	6	11.7 Å²	11.7	3%	0.031	6%	0.063	C	C	.	.	H	α-helix	trans	-62.1	-51.7	173.9	-67.8	163.3	0	0	0	110.7	M106 Q107 E108 T112 A113 I114 T368 L380 L383 L387	M106-I110 WeakPolarHBondContact O-CD1 3.45Å; M106-I110 WeakPolarHBondContact O-CG1 3.49Å; M106-I110 PolarHBondContact O-N 3.23Å; Q107-I110 PolarHBondContact O-N 3.3Å; E108-I110 VanDerWaalsContact C-N 3.31Å; E108-I110 PolarHBondContact O-N 2.98Å; I110-T112 VanDerWaalsContact C-N 3.34Å; I110-T112 PolarHBondContact O-N 3.35Å; I110-A113 PolarHBondContact O-N 3.48Å; I110-I114 HydrophobicContact CG2-CD1 3.74Å; I110-I114 HydrophobicContact CG2-CG1 4.49Å; I110-I114 WeakPolarHBondContact O-CB 3.29Å; I110-I114 VanDerWaalsContact O-CG1 3.29Å; I110-I114 WeakPolarHBondContact O-CG1 3.34Å; I110-I114 PolarHBondContact O-N 3.27Å; I110-T368 HydrophobicContact CD1-CG2 4.42Å; I110-T368 HydrophobicContact CG1-CG2 3.64Å; I110-L380 HydrophobicContact CG1-CD2 4.41Å; I110-L383 HydrophobicContact CD1-CD2 3.99Å; I110-L383 HydrophobicContact CD1-CG 4.16Å; I110-L387 HydrophobicContact CD1-CD1 4.31Å
111	G	89.9	Confident	90.1	Very high	5 Å²	5	13.7 Å²	13.7	5%	0.052	8%	0.08	C	C	.	.	H	α-helix	trans	-59.9	-42.2	179	0	0	0	0	0	112.9	Q107 E108 I114 S115 L324	Q107-G111 PolarHBondContact O-N 3.34Å; E108-G111 PolarHBondContact O-N 3.43Å; G111-I114 PolarHBondContact O-N 3.26Å; G111-S115 PolarHBondContact O-N 3.09Å; G111-L324 VanDerWaalsContact O-CD2 3.32Å; G111-L324 WeakPolarHBondContact O-CD2 3.45Å; G111-L324 WeakPolarHBondContact O-CG 3.48Å
112	T	90.8	Very high	89.6	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-65.4	-44.2	177.3	-56.7	0	0	0	0	111.3	E108 I110 I114 S115 F116 T133 L325	E108-T112 VanDerWaalsContact O-CB 3.31Å; E108-T112 WeakPolarHBondContact O-CB 3.33Å; E108-T112 PolarHBondContact O-N 2.93Å; E108-T112 PolarHBondContact O-OG1 3.33Å; I110-T112 VanDerWaalsContact C-N 3.34Å; I110-T112 PolarHBondContact O-N 3.35Å; T112-I114 PolarHBondContact O-N 3.06Å; T112-S115 PolarHBondContact O-N 3.01Å; T112-S115 PolarHBondContact O-OG 3.01Å; T112-F116 HydrophobicContact CG2-CD2 4.01Å; T112-F116 HydrophobicContact CG2-CE2 3.64Å; T112-F116 WeakPolarHBondContact O-CD2 3.1Å; T112-F116 PolarHBondContact O-N 3.29Å; T112-F116 VanDerWaalsContact O-N 3.08Å; T112-T133 HydrophobicContact CG2-CG2 3.7Å; T112-L325 HydrophobicContact CG2-CD1 3.89Å
113	A	90.3	Very high	89.4	Confident	2 Å²	2	24.2 Å²	24.2	2%	0.017	13%	0.128	C	C	.	.	H	α-helix	trans	-62.4	-41.3	175.4	0	0	0	0	0	112.7	V109 I110 S115 F116 N117 L126 V130	V109-A113 VanDerWaalsContact O-CB 3.31Å; V109-A113 WeakPolarHBondContact O-CB 3.43Å; V109-A113 PolarHBondContact O-N 3.4Å; I110-A113 PolarHBondContact O-N 3.48Å; A113-S115 VanDerWaalsContact C-N 3.33Å; A113-S115 PolarHBondContact O-N 3Å; A113-F116 PolarHBondContact O-N 3.35Å; A113-N117 PolarHBondContact O-N 2.89Å; A113-L126 HydrophobicContact CB-CD2 4.39Å; A113-L126 WeakPolarHBondContact O-CD2 3.48Å; A113-V130 HydrophobicContact CB-CB 4.44Å; A113-V130 HydrophobicContact CB-CG2 3.56Å
114	I	89.4	Confident	89.2	Confident	4 Å²	4	26.4 Å²	26.4	2%	0.021	14%	0.139	C	C	.	.	H	α-helix	trans	-59.2	-44.6	173.1	-72.8	169.9	0	0	0	110.6	I110 G111 T112 F116 N117 L118 L126 I301 Y302 L324	I110-I114 HydrophobicContact CG2-CD1 3.74Å; I110-I114 HydrophobicContact CG2-CG1 4.49Å; I110-I114 WeakPolarHBondContact O-CB 3.29Å; I110-I114 VanDerWaalsContact O-CG1 3.29Å; I110-I114 WeakPolarHBondContact O-CG1 3.34Å; I110-I114 PolarHBondContact O-N 3.27Å; G111-I114 PolarHBondContact O-N 3.26Å; T112-I114 PolarHBondContact O-N 3.06Å; I114-F116 PolarHBondContact O-N 3.12Å; I114-N117 PolarHBondContact O-N 3.47Å; I114-L118 HydrophobicContact CG2-CD1 4.11Å; I114-L118 WeakPolarHBondContact O-CG 3.35Å; I114-L118 PolarHBondContact O-N 3.1Å; I114-L126 HydrophobicContact CG1-CD1 4.49Å; I114-L126 HydrophobicContact CG1-CD2 4.02Å; I114-I301 HydrophobicContact CG2-CG2 4.4Å; I114-Y302 HydrophobicContact CG2-CD2 4.04Å; I114-L324 HydrophobicContact CB-CD2 4.03Å; I114-L324 HydrophobicContact CG2-CD2 3.54Å
115	S	92.8	Very high	89.1	Confident	0 Å²	0	29.2 Å²	29.2	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-60.5	-43.3	178.2	80	0	0	0	0	112.4	G111 T112 A113 N117 L118 L119 A321 L325	G111-S115 PolarHBondContact O-N 3.09Å; T112-S115 PolarHBondContact O-N 3.01Å; T112-S115 PolarHBondContact O-OG 3.01Å; A113-S115 VanDerWaalsContact C-N 3.33Å; A113-S115 PolarHBondContact O-N 3Å; S115-N117 PolarHBondContact O-N 3.21Å; S115-L118 PolarHBondContact O-N 3.3Å; S115-L119 WeakPolarHBondContact O-CB 3.49Å; S115-L119 VanDerWaalsContact O-CG 3.25Å; S115-L119 WeakPolarHBondContact O-CG 3.42Å; S115-L119 PolarHBondContact O-N 3.36Å; S115-A321 WeakPolarHBondContact CB-O 3.25Å; S115-L325 WeakPolarHBondContact OG-CB 3.42Å
116	F	92.6	Very high	88.9	Confident	52 Å²	52	29.9 Å²	29.9	23%	0.228	16%	0.16	C	C	.	.	H	α-helix	trans	-66.3	-36	176.6	-76.7	-58.6	0	0	0	112.9	T112 A113 I114 S120 I132 L325	T112-F116 HydrophobicContact CG2-CD2 4.01Å; T112-F116 HydrophobicContact CG2-CE2 3.64Å; T112-F116 WeakPolarHBondContact O-CD2 3.1Å; T112-F116 PolarHBondContact O-N 3.29Å; T112-F116 VanDerWaalsContact O-N 3.08Å; A113-F116 PolarHBondContact O-N 3.35Å; I114-F116 PolarHBondContact O-N 3.12Å; F116-S120 WeakPolarHBondContact O-CB 3.41Å; F116-S120 PolarHBondContact O-N 3.48Å; F116-S120 PolarHBondContact O-OG 3.11Å; F116-I132 HydrophobicContact CD2-CB 4.48Å; F116-I132 HydrophobicContact CD2-CG2 4.11Å; F116-I132 HydrophobicContact CE1-CG2 4.42Å; F116-I132 HydrophobicContact CE2-CB 4.29Å; F116-I132 HydrophobicContact CE2-CG2 3.52Å; F116-I132 HydrophobicContact CZ-CG2 3.71Å; F116-L325 HydrophobicContact CE2-CD1 4.3Å; F116-L325 HydrophobicContact CZ-CD1 4.15Å
117	N	90.5	Very high	88.7	Confident	12 Å²	12	33.7 Å²	33.7	6%	0.064	17%	0.174	C	C	.	.	H	α-helix	trans	-64.7	-43.7	174.4	-175.7	-95	0	0	0	111.8	A113 I114 S115 S120 G122 I124 L126 Y302	A113-N117 PolarHBondContact O-N 2.89Å; I114-N117 PolarHBondContact O-N 3.47Å; S115-N117 PolarHBondContact O-N 3.21Å; N117-S120 PolarHBondContact O-OG 2.8Å; N117-G122 WeakPolarHBondContact O-CA 3.38Å; N117-G122 PolarHBondContact O-N 2.67Å; N117-I124 PolarHBondContact ND2-O 2.8Å; N117-L126 HydrophobicContact CB-CD2 3.68Å; N117-Y302 WeakPolarHBondContact OD1-CE2 2.99Å; N117-Y302 PolarHBondContact OD1-OH 2.94Å; N117-Y302 VanDerWaalsContact OD1-OH 3.06Å
118	L	90.3	Very high	88.7	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-66.6	-49.9	176.9	-67.9	175.3	0	0	0	111.8	I114 S115 S120 A121 Y302 V306 L317 A321	I114-L118 HydrophobicContact CG2-CD1 4.11Å; I114-L118 WeakPolarHBondContact O-CG 3.35Å; I114-L118 PolarHBondContact O-N 3.1Å; S115-L118 PolarHBondContact O-N 3.3Å; L118-S120 VanDerWaalsContact C-N 3.31Å; L118-S120 PolarHBondContact O-N 3.35Å; L118-A121 PolarHBondContact O-N 3.44Å; L118-A121 VanDerWaalsContact O-N 3.13Å; L118-Y302 HydrophobicContact CD1-CD2 4.43Å; L118-Y302 HydrophobicContact CD2-CD2 3.81Å; L118-Y302 HydrophobicContact CD2-CE2 3.6Å; L118-Y302 HydrophobicContact CG-CD2 4.05Å; L118-Y302 HydrophobicContact CG-CE2 4.09Å; L118-V306 HydrophobicContact CD2-CG2 3.98Å; L118-L317 HydrophobicContact CB-CD2 4Å; L118-L317 HydrophobicContact CD2-CD1 4.23Å; L118-L317 HydrophobicContact CD2-CD2 4.29Å; L118-L317 HydrophobicContact CD2-CG 4.25Å; L118-A321 HydrophobicContact CB-CB 3.68Å; L118-A321 HydrophobicContact CD1-CB 4.26Å
119	L	92.5	Very high	88.7	Confident	58 Å²	58	35.1 Å²	35.1	30%	0.304	18%	0.182	S	C	.	.	H	α-helix	trans	-60.5	-36.3	178.7	-71.3	172.5	0	0	0	113.2	S115 A121 Y318 A321 V322 L325	S115-L119 WeakPolarHBondContact O-CB 3.49Å; S115-L119 VanDerWaalsContact O-CG 3.25Å; S115-L119 WeakPolarHBondContact O-CG 3.42Å; S115-L119 PolarHBondContact O-N 3.36Å; L119-A121 PolarHBondContact O-N 3.07Å; L119-Y318 HydrophobicContact CD2-CD1 4.28Å; L119-A321 HydrophobicContact CD2-CB 3.86Å; L119-A321 HydrophobicContact CG-CB 3.79Å; L119-V322 HydrophobicContact CD2-CG2 3.99Å; L119-L325 HydrophobicContact CD1-CD2 4.04Å
120	S	89.8	Confident	88.6	Confident	18 Å²	18	35.1 Å²	35.1	13%	0.126	18%	0.182	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.7	2.9	179.8	66.7	0	0	0	0	114.3	F116 N117 L118 G122 R123 I124	F116-S120 WeakPolarHBondContact O-CB 3.41Å; F116-S120 PolarHBondContact O-N 3.48Å; F116-S120 PolarHBondContact O-OG 3.11Å; N117-S120 PolarHBondContact O-OG 2.8Å; L118-S120 VanDerWaalsContact C-N 3.31Å; L118-S120 PolarHBondContact O-N 3.35Å; S120-G122 VanDerWaalsContact C-N 3.29Å; S120-G122 PolarHBondContact O-N 3.13Å; S120-R123 WeakPolarHBondContact O-CB 3.24Å; S120-R123 VanDerWaalsContact O-CG 3.3Å; S120-R123 WeakPolarHBondContact O-CG 3.19Å; S120-R123 PolarHBondContact O-N 2.9Å; S120-R123 PolarHBondContact OG-N 3.16Å; S120-I124 WeakPolarHBondContact OG-CB 3.4Å; S120-I124 PolarHBondContact OG-N 3.47Å
121	A	84.1	Confident	88.6	Confident	43 Å²	43	37.8 Å²	37.8	36%	0.355	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	56	39.9	-171.2	0	0	0	0	0	113.3	L118 L119 R123 Y286	L118-A121 PolarHBondContact O-N 3.44Å; L118-A121 VanDerWaalsContact O-N 3.13Å; L119-A121 PolarHBondContact O-N 3.07Å; A121-R123 VanDerWaalsContact C-N 3.31Å; A121-R123 PolarHBondContact O-N 3.4Å; A121-Y286 WeakPolarHBondContact CA-OH 3.36Å
122	G	81.9	Confident	88.6	Confident	38 Å²	38	40.3 Å²	40.3	39%	0.392	21%	0.208	S	C	.	.	T	Hydrogen-bonded Turn	trans	77.9	5.6	-178.7	0	0	0	0	0	115.4	N117 S120	N117-G122 WeakPolarHBondContact O-CA 3.38Å; N117-G122 PolarHBondContact O-N 2.67Å; S120-G122 VanDerWaalsContact C-N 3.29Å; S120-G122 PolarHBondContact O-N 3.13Å
123	R	86.2	Confident	88.5	Confident	211 Å²	211	40.3 Å²	40.3	80%	0.796	21%	0.208	S	C	*	.			trans	-72.6	-32.9	178.1	-67.6	-175.1	-174.9	106.1	-7.1	113.5	S120 A121 P125	S120-R123 WeakPolarHBondContact O-CB 3.24Å; S120-R123 VanDerWaalsContact O-CG 3.3Å; S120-R123 WeakPolarHBondContact O-CG 3.19Å; S120-R123 PolarHBondContact O-N 2.9Å; S120-R123 PolarHBondContact OG-N 3.16Å; A121-R123 VanDerWaalsContact C-N 3.31Å; A121-R123 PolarHBondContact O-N 3.4Å; R123-P125 WeakPolarHBondContact O-CD 3.44Å
124	I	87.9	Confident	88.2	Confident	49 Å²	49	43.3 Å²	43.3	25%	0.251	22%	0.223	S	C	.	.	S	Bend	trans	-94.2	111.2	174.7	-59.3	175	0	0	0	107.2	N117 S120 D128 I132	N117-I124 PolarHBondContact ND2-O 2.8Å; S120-I124 WeakPolarHBondContact OG-CB 3.4Å; S120-I124 PolarHBondContact OG-N 3.47Å; I124-D128 HydrophobicContact CG2-CB 3.75Å; I124-I132 HydrophobicContact CD1-CD1 4.3Å; I124-I132 HydrophobicContact CG2-CD1 4.09Å
125	P	87	Confident	88.1	Confident	61 Å²	61	47.8 Å²	47.8	40%	0.396	25%	0.25	S	S	.	.			trans	-65.7	158.4	174.5	29.6	-35.4	0	0	0	110.8	R123 W127 D128 G129	R123-P125 WeakPolarHBondContact O-CD 3.44Å; P125-W127 VanDerWaalsContact C-N 3.26Å; P125-W127 PolarHBondContact O-N 3.15Å; P125-D128 VanDerWaalsContact CD-OD2 3.26Å; P125-D128 WeakPolarHBondContact CD-OD2 3.16Å; P125-D128 HydrophobicContact CG-CB 3.96Å; P125-D128 VanDerWaalsContact CG-OD2 3.25Å; P125-D128 WeakPolarHBondContact CG-OD2 3.36Å; P125-D128 PolarHBondContact O-N 3.3Å; P125-D128 VanDerWaalsContact O-N 3.13Å; P125-G129 PolarHBondContact O-N 2.64Å
126	L	85.3	Confident	87.6	Confident	16 Å²	16	48.6 Å²	48.6	8%	0.084	26%	0.255	C	S	.	.	H	α-helix	trans	-57.9	-36.7	-176	-70.8	-171	0	0	0	113.2	A113 I114 N117 D128 G129 V130 L377 L380	A113-L126 HydrophobicContact CB-CD2 4.39Å; A113-L126 WeakPolarHBondContact O-CD2 3.48Å; I114-L126 HydrophobicContact CG1-CD1 4.49Å; I114-L126 HydrophobicContact CG1-CD2 4.02Å; N117-L126 HydrophobicContact CB-CD2 3.68Å; L126-D128 PolarHBondContact O-N 3.27Å; L126-G129 CarbonylContact O-C 3.55Å; L126-G129 WeakPolarHBondContact O-CA 3.3Å; L126-G129 PolarHBondContact O-N 3.37Å; L126-G129 VanDerWaalsContact O-N 3.16Å; L126-V130 WeakPolarHBondContact O-CG2 3.26Å; L126-V130 PolarHBondContact O-N 3.21Å; L126-L377 HydrophobicContact CD1-CD2 3.36Å; L126-L377 HydrophobicContact CG-CD2 3.85Å; L126-L380 HydrophobicContact CB-CD1 4.31Å; L126-L380 HydrophobicContact CD1-CD1 3.48Å; L126-L380 VanDerWaalsContact CD1-CD1 3.48Å
127	W	86.6	Confident	87	Confident	101 Å²	101	46.3 Å²	46.3	38%	0.383	25%	0.245	S	C	.	.	H	α-helix	trans	-61.7	-43.9	177	178.4	62.6	0	0	0	113.1	P125 G129 V130 L131 V369 A372 V373	P125-W127 VanDerWaalsContact C-N 3.26Å; P125-W127 PolarHBondContact O-N 3.15Å; W127-G129 VanDerWaalsContact C-N 3.3Å; W127-G129 PolarHBondContact O-N 3.17Å; W127-V130 WeakPolarHBondContact O-CB 3.29Å; W127-V130 PolarHBondContact O-N 3.33Å; W127-L131 HydrophobicContact CD2-CD1 4.13Å; W127-L131 HydrophobicContact CE3-CD1 4.23Å; W127-L131 HydrophobicContact CH2-CD1 3.78Å; W127-L131 HydrophobicContact CZ2-CD1 3.63Å; W127-L131 HydrophobicContact CZ2-CG 4.4Å; W127-L131 HydrophobicContact CZ3-CD1 4.06Å; W127-L131 PolarHBondContact O-N 3.35Å; W127-V369 VanDerWaalsContact NE1-CG1 3.28Å; W127-A372 HydrophobicContact CB-CB 4.17Å; W127-V373 HydrophobicContact CB-CG2 4.23Å; W127-V373 HydrophobicContact CD2-CG2 3.84Å; W127-V373 HydrophobicContact CG-CG2 3.51Å
128	D	88.2	Confident	86.6	Confident	61 Å²	61	50.9 Å²	50.9	33%	0.326	26%	0.264	S	S	.	.	H	α-helix	trans	-64.1	-38.7	173.9	-70.4	-12.4	0	0	0	110.6	I124 P125 L126 V130 L131 I132	I124-D128 HydrophobicContact CG2-CB 3.75Å; P125-D128 VanDerWaalsContact CD-OD2 3.26Å; P125-D128 WeakPolarHBondContact CD-OD2 3.16Å; P125-D128 HydrophobicContact CG-CB 3.96Å; P125-D128 VanDerWaalsContact CG-OD2 3.25Å; P125-D128 WeakPolarHBondContact CG-OD2 3.36Å; P125-D128 PolarHBondContact O-N 3.3Å; P125-D128 VanDerWaalsContact O-N 3.13Å; L126-D128 PolarHBondContact O-N 3.27Å; D128-V130 VanDerWaalsContact C-N 3.32Å; D128-V130 PolarHBondContact O-N 3.4Å; D128-L131 PolarHBondContact O-N 2.95Å; D128-L131 VanDerWaalsContact O-N 3.16Å; D128-I132 VanDerWaalsContact O-CG1 3.27Å; D128-I132 WeakPolarHBondContact O-CG1 3.36Å; D128-I132 PolarHBondContact O-N 3.21Å
129	G	88.2	Confident	86.3	Confident	0 Å²	0	55.4 Å²	55.4	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-57.8	-40.9	172.1	0	0	0	0	0	113.2	P125 L126 W127 I132 T133	P125-G129 PolarHBondContact O-N 2.64Å; L126-G129 CarbonylContact O-C 3.55Å; L126-G129 WeakPolarHBondContact O-CA 3.3Å; L126-G129 PolarHBondContact O-N 3.37Å; L126-G129 VanDerWaalsContact O-N 3.16Å; W127-G129 VanDerWaalsContact C-N 3.3Å; W127-G129 PolarHBondContact O-N 3.17Å; G129-I132 PolarHBondContact O-N 3.06Å; G129-T133 WeakPolarHBondContact O-CG2 3.37Å
130	V	88.3	Confident	85.7	Confident	1 Å²	1	53 Å²	53	1%	0.006	27%	0.271	C	S	.	.	H	α-helix	trans	-67.5	-37.6	174.4	171.1	0	0	0	0	111.4	V109 A113 L126 W127 D128 I132 T133 I365 T368 V369	V109-V130 HydrophobicContact CG1-CB 4.29Å; V109-V130 HydrophobicContact CG1-CG1 3.73Å; V109-V130 HydrophobicContact CG1-CG2 4.11Å; A113-V130 HydrophobicContact CB-CB 4.44Å; A113-V130 HydrophobicContact CB-CG2 3.56Å; L126-V130 WeakPolarHBondContact O-CG2 3.26Å; L126-V130 PolarHBondContact O-N 3.21Å; W127-V130 WeakPolarHBondContact O-CB 3.29Å; W127-V130 PolarHBondContact O-N 3.33Å; D128-V130 VanDerWaalsContact C-N 3.32Å; D128-V130 PolarHBondContact O-N 3.4Å; V130-I132 VanDerWaalsContact C-N 3.33Å; V130-T133 PolarHBondContact O-N 3.4Å; V130-T133 PolarHBondContact O-OG1 3.46Å; V130-I365 HydrophobicContact CG1-CG2 4.03Å; V130-T368 HydrophobicContact CG1-CG2 4.29Å; V130-T368 HydrophobicContact CG2-CG2 3.91Å; V130-V369 HydrophobicContact CB-CG2 4.47Å; V130-V369 HydrophobicContact CG1-CG2 3.53Å
131	L	88.8	Confident	85.1	Confident	61 Å²	61	52.3 Å²	52.3	32%	0.319	27%	0.266	S	S	.	.	H	α-helix	trans	-68	-32.4	174.7	-68.6	-180	0	0	0	112.6	W127 D128 T133 I134 V369	W127-L131 HydrophobicContact CD2-CD1 4.13Å; W127-L131 HydrophobicContact CE3-CD1 4.23Å; W127-L131 HydrophobicContact CH2-CD1 3.78Å; W127-L131 HydrophobicContact CZ2-CD1 3.63Å; W127-L131 HydrophobicContact CZ2-CG 4.4Å; W127-L131 HydrophobicContact CZ3-CD1 4.06Å; W127-L131 PolarHBondContact O-N 3.35Å; D128-L131 PolarHBondContact O-N 2.95Å; D128-L131 VanDerWaalsContact O-N 3.16Å; L131-T133 VanDerWaalsContact C-N 3.25Å; L131-T133 PolarHBondContact O-N 3.42Å; L131-I134 HydrophobicContact CD2-CD1 4.03Å; L131-I134 VanDerWaalsContact O-CB 3.29Å; L131-I134 WeakPolarHBondContact O-CB 3.26Å; L131-I134 WeakPolarHBondContact O-CG1 3.27Å; L131-I134 PolarHBondContact O-N 3.16Å; L131-V369 HydrophobicContact CD2-CG2 4.24Å
132	I	89.3	Confident	85.1	Confident	58 Å²	58	55.5 Å²	55.5	30%	0.297	27%	0.272	S	S	.	.	H	α-helix	trans	-65.1	-27	177.6	-69.7	162.1	0	0	0	111.8	F116 I124 D128 G129 V130 I134 V135 D136	F116-I132 HydrophobicContact CD2-CB 4.48Å; F116-I132 HydrophobicContact CD2-CG2 4.11Å; F116-I132 HydrophobicContact CE1-CG2 4.42Å; F116-I132 HydrophobicContact CE2-CB 4.29Å; F116-I132 HydrophobicContact CE2-CG2 3.52Å; F116-I132 HydrophobicContact CZ-CG2 3.71Å; I124-I132 HydrophobicContact CD1-CD1 4.3Å; I124-I132 HydrophobicContact CG2-CD1 4.09Å; D128-I132 VanDerWaalsContact O-CG1 3.27Å; D128-I132 WeakPolarHBondContact O-CG1 3.36Å; D128-I132 PolarHBondContact O-N 3.21Å; G129-I132 PolarHBondContact O-N 3.06Å; V130-I132 VanDerWaalsContact C-N 3.33Å; I132-I134 PolarHBondContact O-N 3.14Å; I132-V135 VanDerWaalsContact O-CB 3.3Å; I132-V135 WeakPolarHBondContact O-CB 2.98Å; I132-V135 PolarHBondContact O-N 3.04Å; I132-D136 PolarHBondContact O-N 2.89Å
133	T	88	Confident	84.9	Confident	1 Å²	1	55.5 Å²	55.5	1%	0.006	26%	0.263	C	S	.	.	H	α-helix	trans	-67.5	-17	176.6	75.7	0	0	0	0	113.6	V109 T112 G129 V130 L131 V135 D136 T137	V109-T133 HydrophobicContact CG1-CG2 4.2Å; T112-T133 HydrophobicContact CG2-CG2 3.7Å; G129-T133 WeakPolarHBondContact O-CG2 3.37Å; V130-T133 PolarHBondContact O-N 3.4Å; V130-T133 PolarHBondContact O-OG1 3.46Å; L131-T133 VanDerWaalsContact C-N 3.25Å; L131-T133 PolarHBondContact O-N 3.42Å; T133-V135 PolarHBondContact O-N 2.79Å; T133-D136 PolarHBondContact O-N 3.2Å; T133-T137 PolarHBondContact O-N 2.76Å; T133-T137 PolarHBondContact O-OG1 3.03Å
134	I	85.6	Confident	84.3	Confident	65 Å²	65	46.5 Å²	46.5	33%	0.333	23%	0.231	S	C	.	.	H	α-helix	trans	-62.7	-35.5	168.2	-56.6	171.4	0	0	0	110	L131 I132 T137 F138 I365	L131-I134 HydrophobicContact CD2-CD1 4.03Å; L131-I134 VanDerWaalsContact O-CB 3.29Å; L131-I134 WeakPolarHBondContact O-CB 3.26Å; L131-I134 WeakPolarHBondContact O-CG1 3.27Å; L131-I134 PolarHBondContact O-N 3.16Å; I132-I134 PolarHBondContact O-N 3.14Å; I134-T137 VanDerWaalsContact O-CB 3.32Å; I134-T137 WeakPolarHBondContact O-CB 3.34Å; I134-T137 PolarHBondContact O-N 3.33Å; I134-F138 HydrophobicContact CG2-CD2 4.43Å; I134-F138 HydrophobicContact CG2-CE2 3.89Å; I134-F138 WeakPolarHBondContact O-CD2 3.29Å; I134-F138 PolarHBondContact O-N 2.9Å; I134-I365 HydrophobicContact CG1-CD1 3.69Å; I134-I365 HydrophobicContact CG1-CG2 4.46Å
135	V	86	Confident	84	Confident	97 Å²	97	48.6 Å²	48.6	59%	0.588	24%	0.242	S	C	*	.	H	α-helix	trans	-71.7	-40.6	178.4	-173.7	0	0	0	0	111.3	I132 T133 T137 F138 F139	I132-V135 VanDerWaalsContact O-CB 3.3Å; I132-V135 WeakPolarHBondContact O-CB 2.98Å; I132-V135 PolarHBondContact O-N 3.04Å; T133-V135 PolarHBondContact O-N 2.79Å; V135-T137 VanDerWaalsContact C-N 3.3Å; V135-T137 PolarHBondContact O-N 3.05Å; V135-F138 PolarHBondContact O-N 3.44Å; V135-F138 VanDerWaalsContact O-N 3.11Å; V135-F139 PolarHBondContact O-N 2.83Å
136	D	82.8	Confident	83.6	Confident	18 Å²	18	51.3 Å²	51.3	10%	0.096	25%	0.246	C	C	.	.	H	α-helix	trans	-55.3	-45.8	170.8	166	28.3	0	0	0	111.1	I132 T133 F138 F139 F140 Q329	I132-D136 PolarHBondContact O-N 2.89Å; T133-D136 PolarHBondContact O-N 3.2Å; D136-F138 PolarHBondContact O-N 2.73Å; D136-F138 VanDerWaalsContact O-N 3.11Å; D136-F139 CarbonylContact O-C 3.59Å; D136-F139 WeakPolarHBondContact O-CA 3.46Å; D136-F139 WeakPolarHBondContact O-CB 3.33Å; D136-F139 PolarHBondContact O-N 2.83Å; D136-F140 PolarHBondContact O-N 3.46Å; D136-Q329 VanDerWaalsContact CG-OE1 3.3Å; D136-Q329 PolarHBondContact OD1-OE1 3.34Å; D136-Q329 PolarHBondContact OD2-NE2 2.99Å
137	T	79.4	Confident	83.4	Confident	3 Å²	3	52.1 Å²	52.1	2%	0.018	26%	0.258	C	S	.	.	H	α-helix	trans	-51.1	-41.6	175.4	-55.9	0	0	0	0	112.7	T133 I134 V135 L141 V357 R361	T133-T137 PolarHBondContact O-N 2.76Å; T133-T137 PolarHBondContact O-OG1 3.03Å; I134-T137 VanDerWaalsContact O-CB 3.32Å; I134-T137 WeakPolarHBondContact O-CB 3.34Å; I134-T137 PolarHBondContact O-N 3.33Å; V135-T137 VanDerWaalsContact C-N 3.3Å; V135-T137 PolarHBondContact O-N 3.05Å; T137-L141 HydrophobicContact CG2-CD1 4.26Å; T137-L141 WeakPolarHBondContact O-CB 3.13Å; T137-L141 WeakPolarHBondContact O-CD1 3.5Å; T137-L141 VanDerWaalsContact O-CG 3.29Å; T137-L141 WeakPolarHBondContact O-CG 3.44Å; T137-L141 PolarHBondContact O-N 3.34Å; T137-L141 VanDerWaalsContact O-N 3.12Å; T137-V357 HydrophobicContact CG2-CG1 3.49Å; T137-V357 VanDerWaalsContact CG2-CG1 3.49Å; T137-R361 HydrophobicContact CG2-CB 4.39Å; T137-R361 HydrophobicContact CG2-CG 3.76Å; T137-R361 WeakPolarHBondContact OG1-CD 3.34Å
138	F	82.9	Confident	83	Confident	108 Å²	108	50.1 Å²	50.1	47%	0.474	25%	0.254	S	S	.	.	H	α-helix	trans	-72.4	-35.3	175.2	-69.2	-67	0	0	0	113.2	I134 V135 D136 L141 F142 L358	I134-F138 HydrophobicContact CG2-CD2 4.43Å; I134-F138 HydrophobicContact CG2-CE2 3.89Å; I134-F138 WeakPolarHBondContact O-CD2 3.29Å; I134-F138 PolarHBondContact O-N 2.9Å; V135-F138 PolarHBondContact O-N 3.44Å; V135-F138 VanDerWaalsContact O-N 3.11Å; D136-F138 PolarHBondContact O-N 2.73Å; D136-F138 VanDerWaalsContact O-N 3.11Å; F138-L141 PolarHBondContact O-N 2.7Å; F138-F142 WeakPolarHBondContact O-CB 3.29Å; F138-F142 PolarHBondContact O-N 2.91Å; F138-L358 HydrophobicContact CE1-CD2 4.31Å; F138-L358 HydrophobicContact CZ-CD2 4.19Å
139	F	83.4	Confident	82.6	Confident	96 Å²	96	57.1 Å²	57.1	42%	0.421	28%	0.276	S	S	.	.	H	α-helix	trans	-65	-43.1	174.4	178.2	-106.2	0	0	0	112.1	V135 D136 F142 L143 F154	V135-F139 PolarHBondContact O-N 2.83Å; D136-F139 CarbonylContact O-C 3.59Å; D136-F139 WeakPolarHBondContact O-CA 3.46Å; D136-F139 WeakPolarHBondContact O-CB 3.33Å; D136-F139 PolarHBondContact O-N 2.83Å; F139-F142 WeakPolarHBondContact O-CB 3.37Å; F139-F142 PolarHBondContact O-N 2.96Å; F139-L143 HydrophobicContact CD1-CD1 4.04Å; F139-L143 HydrophobicContact CE1-CD1 3.45Å; F139-L143 VanDerWaalsContact CE1-CD1 3.45Å; F139-L143 HydrophobicContact CE1-CG 4.22Å; F139-L143 HydrophobicContact CZ-CD1 3.75Å; F139-L143 HydrophobicContact CZ-CD2 4.48Å; F139-L143 HydrophobicContact CZ-CG 4.16Å; F139-L143 PolarHBondContact O-N 3.18Å; F139-F154 HydrophobicContact CE1-CZ 4.19Å
140	F	79.3	Confident	82.5	Confident	7 Å²	7	63.5 Å²	63.5	3%	0.031	30%	0.304	C	S	.	.	H	α-helix	trans	-59.5	-48.9	171.4	169.4	-111.4	0	0	0	112	D136 F142 L143 D144 L151 T332 M333 T336 Y337	D136-F140 PolarHBondContact O-N 3.46Å; F140-F142 PolarHBondContact O-N 2.7Å; F140-L143 WeakPolarHBondContact O-CA 3.42Å; F140-L143 PolarHBondContact O-N 2.96Å; F140-D144 PolarHBondContact O-N 2.75Å; F140-L151 HydrophobicContact CE2-CD1 4.15Å; F140-T332 HydrophobicContact CB-CG2 4.43Å; F140-T332 HydrophobicContact CG-CG2 4.48Å; F140-M333 HydrophobicContact CD2-CB 4.03Å; F140-M333 HydrophobicContact CD2-CE 3.75Å; F140-M333 HydrophobicContact CD2-CG 3.52Å; F140-M333 HydrophobicContact CD2-SD 4.43Å; F140-M333 HydrophobicContact CE2-CB 3.71Å; F140-M333 HydrophobicContact CE2-CE 3.86Å; F140-M333 HydrophobicContact CE2-CG 3.74Å; F140-M333 HydrophobicContact CG-CG 4.37Å; F140-M333 HydrophobicContact CZ-CB 4.44Å; F140-T336 HydrophobicContact CD1-CG2 4.4Å; F140-T336 HydrophobicContact CE1-CG2 4.07Å; F140-T336 WeakPolarHBondContact CE1-OG1 3.03Å; F140-T336 VanDerWaalsContact CZ-OG1 3.22Å; F140-T336 WeakPolarHBondContact CZ-OG1 3.49Å; F140-Y337 HydrophobicContact CE2-CE2 4.25Å; F140-Y337 HydrophobicContact CZ-CE2 4.12Å
141	L	78.8	Confident	82.2	Confident	4 Å²	4	63.8 Å²	63.8	2%	0.021	31%	0.306	C	S	.	.	H	α-helix	trans	-60.9	-29	177.3	-76	165.7	0	0	0	112.6	T137 F138 N145 F354 V357	T137-L141 HydrophobicContact CG2-CD1 4.26Å; T137-L141 WeakPolarHBondContact O-CB 3.13Å; T137-L141 WeakPolarHBondContact O-CD1 3.5Å; T137-L141 VanDerWaalsContact O-CG 3.29Å; T137-L141 WeakPolarHBondContact O-CG 3.44Å; T137-L141 PolarHBondContact O-N 3.34Å; T137-L141 VanDerWaalsContact O-N 3.12Å; F138-L141 PolarHBondContact O-N 2.7Å; L141-N145 PolarHBondContact O-ND2 2.96Å; L141-F354 HydrophobicContact CB-CD1 4.45Å; L141-F354 HydrophobicContact CB-CE1 3.91Å; L141-F354 HydrophobicContact CB-CZ 4.35Å; L141-F354 HydrophobicContact CD1-CD1 3.77Å; L141-F354 HydrophobicContact CD1-CE1 4.04Å; L141-F354 HydrophobicContact CD2-CD1 4.2Å; L141-F354 HydrophobicContact CD2-CE1 4.32Å; L141-F354 HydrophobicContact CD2-CG 4.38Å; L141-F354 HydrophobicContact CG-CD1 4.38Å; L141-F354 HydrophobicContact CG-CE1 4.33Å; L141-V357 HydrophobicContact CD1-CB 4.4Å; L141-V357 HydrophobicContact CD1-CG1 4.05Å; L141-V357 HydrophobicContact CD2-CB 4.12Å; L141-V357 HydrophobicContact CD2-CG1 4.27Å; L141-V357 HydrophobicContact CD2-CG2 4.06Å; L141-V357 HydrophobicContact CG-CG1 4.17Å
142	F	82.3	Confident	81.9	Confident	109 Å²	109	64.1 Å²	64.1	48%	0.478	31%	0.305	S	S	.	.	H	α-helix	trans	-70.2	-45.8	170.4	178.1	-103.5	0	0	0	111.7	F138 F139 F140 N145 Y146	F138-F142 WeakPolarHBondContact O-CB 3.29Å; F138-F142 PolarHBondContact O-N 2.91Å; F139-F142 WeakPolarHBondContact O-CB 3.37Å; F139-F142 PolarHBondContact O-N 2.96Å; F140-F142 PolarHBondContact O-N 2.7Å; F142-N145 PolarHBondContact O-N 3.16Å; F142-N145 PolarHBondContact O-ND2 3.37Å; F142-Y146 HydrophobicContact CD1-CE2 4.04Å; F142-Y146 AromaticContact CE1-CE2 3.61Å; F142-Y146 HydrophobicContact CE1-CE2 3.61Å; F142-Y146 HydrophobicContact CE2-CE2 4.21Å; F142-Y146 AromaticContact CZ-CE2 3.71Å; F142-Y146 HydrophobicContact CZ-CE2 3.71Å; F142-Y146 AromaticContact CZ-CZ 3.93Å; F142-Y146 VanDerWaalsContact CZ-OH 3.23Å; F142-Y146 WeakPolarHBondContact CZ-OH 3.31Å; F142-Y146 WeakPolarHBondContact O-CD2 3.24Å
143	L	77.9	Confident	81.9	Confident	39 Å²	39	64.5 Å²	64.5	20%	0.204	32%	0.317	C	S	.	.	H	α-helix	trans	-63.8	-37.4	177.9	-75.1	179.2	0	0	0	114.1	F139 F140 N145 Y146 F154	F139-L143 HydrophobicContact CD1-CD1 4.04Å; F139-L143 HydrophobicContact CE1-CD1 3.45Å; F139-L143 VanDerWaalsContact CE1-CD1 3.45Å; F139-L143 HydrophobicContact CE1-CG 4.22Å; F139-L143 HydrophobicContact CZ-CD1 3.75Å; F139-L143 HydrophobicContact CZ-CD2 4.48Å; F139-L143 HydrophobicContact CZ-CG 4.16Å; F139-L143 PolarHBondContact O-N 3.18Å; F140-L143 WeakPolarHBondContact O-CA 3.42Å; F140-L143 PolarHBondContact O-N 2.96Å; L143-N145 PolarHBondContact O-N 3.13Å; L143-N145 VanDerWaalsContact O-N 3.16Å; L143-Y146 WeakPolarHBondContact O-CB 3.46Å; L143-Y146 PolarHBondContact O-N 2.89Å; L143-F154 HydrophobicContact CD1-CD1 4.2Å; L143-F154 HydrophobicContact CD1-CE1 4.01Å; L143-F154 HydrophobicContact CD1-CE2 4.41Å; L143-F154 HydrophobicContact CD1-CG 4.46Å; L143-F154 HydrophobicContact CD1-CZ 4.13Å
144	D	75.3	Confident	81.9	Confident	22 Å²	22	66.8 Å²	66.8	12%	0.118	33%	0.327	C	S	.	.	H	α-helix	trans	-57.7	-29.6	178.1	180	55.6	0	0	0	112.6	F140 Y146 G147 Y337 R353	F140-D144 PolarHBondContact O-N 2.75Å; D144-Y146 PolarHBondContact O-N 2.68Å; D144-G147 PolarHBondContact O-N 3.37Å; D144-Y337 PolarHBondContact OD1-OH 3.05Å; D144-R353 WeakPolarHBondContact OD2-CD 3.47Å; D144-R353 IonicContact OD2-CZ 3.65Å; D144-R353 IonicContact OD2-NE 3.9Å; D144-R353 IonicContact OD2-NH1 2.67Å; D144-R353 PolarHBondContact OD2-NH1 3.31Å
145	N	80.1	Confident	81.9	Confident	92 Å²	92	65.6 Å²	65.6	49%	0.492	32%	0.319	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.3	-16.8	175.5	-60.2	-60.5	0	0	0	113.9	L141 F142 L143	L141-N145 PolarHBondContact O-ND2 2.96Å; F142-N145 PolarHBondContact O-N 3.16Å; F142-N145 PolarHBondContact O-ND2 3.37Å; L143-N145 PolarHBondContact O-N 3.13Å; L143-N145 VanDerWaalsContact O-N 3.16Å
146	Y	80.1	Confident	82.1	Confident	119 Å²	119	62.5 Å²	62.5	47%	0.467	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87	-4.9	180	-71.1	-86.8	0	0	0	113.9	F142 L143 D144	F142-Y146 HydrophobicContact CD1-CE2 4.04Å; F142-Y146 AromaticContact CE1-CE2 3.61Å; F142-Y146 HydrophobicContact CE1-CE2 3.61Å; F142-Y146 HydrophobicContact CE2-CE2 4.21Å; F142-Y146 AromaticContact CZ-CE2 3.71Å; F142-Y146 HydrophobicContact CZ-CE2 3.71Å; F142-Y146 AromaticContact CZ-CZ 3.93Å; F142-Y146 VanDerWaalsContact CZ-OH 3.23Å; F142-Y146 WeakPolarHBondContact CZ-OH 3.31Å; F142-Y146 WeakPolarHBondContact O-CD2 3.24Å; L143-Y146 WeakPolarHBondContact O-CB 3.46Å; L143-Y146 PolarHBondContact O-N 2.89Å; D144-Y146 PolarHBondContact O-N 2.68Å
147	G	80.5	Confident	82.6	Confident	33 Å²	33	66.2 Å²	66.2	34%	0.34	33%	0.327	S	S	.	.			trans	85	155.7	170.5	0	0	0	0	0	115.4	D144 R149 K150 L151	D144-G147 PolarHBondContact O-N 3.37Å; G147-R149 PolarHBondContact O-N 3.47Å; G147-R149 VanDerWaalsContact O-N 3.11Å; G147-K150 PolarHBondContact O-N 2.96Å; G147-K150 VanDerWaalsContact O-N 3.13Å; G147-L151 PolarHBondContact O-N 3.39Å
148	L	77.1	Confident	83.2	Confident	58 Å²	58	66.6 Å²	66.6	30%	0.304	33%	0.329	S	S	.	.	H	α-helix	trans	-50.8	-43.4	-164	-161.2	78.9	0	0	0	114.9	K150 L151 E152	L148-K150 PolarHBondContact O-N 2.92Å; L148-L151 CarbonylContact O-C 3.57Å; L148-L151 WeakPolarHBondContact O-CA 3.35Å; L148-L151 WeakPolarHBondContact O-CB 3.37Å; L148-L151 PolarHBondContact O-N 3.17Å; L148-L151 VanDerWaalsContact O-N 3.07Å; L148-E152 WeakPolarHBondContact CD2-OE1 3.36Å; L148-E152 HydrophobicContact CG-CG 4.48Å; L148-E152 PolarHBondContact O-N 2.86Å
149	R	81.4	Confident	83.7	Confident	209 Å²	209	64.4 Å²	64.4	79%	0.789	32%	0.321	S	S	*	.	H	α-helix	trans	-63.5	-35.6	-176.4	-66.4	-174.6	-174	173.7	2.1	114	G147 L151 A153	G147-R149 PolarHBondContact O-N 3.47Å; G147-R149 VanDerWaalsContact O-N 3.11Å; R149-L151 VanDerWaalsContact C-N 3.28Å; R149-A153 PolarHBondContact O-N 3.31Å
150	K	85.3	Confident	84.2	Confident	134 Å²	134	63.4 Å²	63.4	58%	0.583	32%	0.323	S	S	*	.	H	α-helix	trans	-73.2	-29.4	176.5	-75.1	177.7	173.3	178.5	0	111.1	G147 L148 A153 F154	G147-K150 PolarHBondContact O-N 2.96Å; G147-K150 VanDerWaalsContact O-N 3.13Å; L148-K150 PolarHBondContact O-N 2.92Å; K150-A153 PolarHBondContact O-N 3.38Å; K150-F154 PolarHBondContact O-N 3.46Å
151	L	81	Confident	85	Confident	7 Å²	7	65.4 Å²	65.4	4%	0.037	33%	0.334	C	S	.	.	H	α-helix	trans	-78.1	-40.3	179.4	-160.5	149.3	0	0	0	111.5	F140 G147 L148 R149 A153 F154 F155 M333 Y337	F140-L151 HydrophobicContact CE2-CD1 4.15Å; G147-L151 PolarHBondContact O-N 3.39Å; L148-L151 CarbonylContact O-C 3.57Å; L148-L151 WeakPolarHBondContact O-CA 3.35Å; L148-L151 WeakPolarHBondContact O-CB 3.37Å; L148-L151 PolarHBondContact O-N 3.17Å; L148-L151 VanDerWaalsContact O-N 3.07Å; R149-L151 VanDerWaalsContact C-N 3.28Å; L151-A153 VanDerWaalsContact C-N 3.27Å; L151-A153 PolarHBondContact O-N 3.2Å; L151-F154 PolarHBondContact O-N 2.88Å; L151-F154 VanDerWaalsContact O-N 3.11Å; L151-F155 HydrophobicContact CD2-CD2 3.71Å; L151-F155 HydrophobicContact CD2-CE2 3.25Å; L151-F155 HydrophobicContact CD2-CZ 3.92Å; L151-F155 WeakPolarHBondContact O-CD2 3.34Å; L151-F155 PolarHBondContact O-N 2.67Å; L151-M333 HydrophobicContact CD1-CE 3.88Å; L151-M333 HydrophobicContact CD2-CE 3.66Å; L151-M333 HydrophobicContact CG-CE 3.49Å; L151-M333 VanDerWaalsContact CG-CE 3.49Å; L151-Y337 HydrophobicContact CD1-CE2 4.03Å; L151-Y337 WeakPolarHBondContact CD1-OH 3.34Å; L151-Y337 HydrophobicContact CD2-CE2 3.75Å
152	E	84	Confident	85.7	Confident	67 Å²	67	66.3 Å²	66.3	31%	0.313	34%	0.338	S	S	.	.	H	α-helix	trans	-52.6	-44.5	165.3	-76	173.3	-154.5	0	0	111.1	L148 F155 G156 R223	L148-E152 WeakPolarHBondContact CD2-OE1 3.36Å; L148-E152 HydrophobicContact CG-CG 4.48Å; L148-E152 PolarHBondContact O-N 2.86Å; E152-F155 PolarHBondContact O-N 2.93Å; E152-G156 PolarHBondContact O-N 3.16Å; E152-R223 IonicContact OE1-CZ 2.75Å; E152-R223 IonicContact OE1-NH1 3.52Å; E152-R223 IonicContact OE1-NH2 3.13Å; E152-R223 IonicContact OE2-CZ 3.66Å; E152-R223 IonicContact OE2-NH1 2.69Å; E152-R223 PolarHBondContact OE2-NH1 3.25Å; E152-R223 IonicContact OE2-NH2 3.34Å; E152-R223 PolarHBondContact OE2-NH2 3.04Å
153	A	87.7	Confident	86.3	Confident	66 Å²	66	62.7 Å²	62.7	55%	0.545	33%	0.328	S	S	.	.	H	α-helix	trans	-67.3	-35.6	176.7	0	0	0	0	0	113.3	R149 K150 L151 G156 L157	R149-A153 PolarHBondContact O-N 3.31Å; K150-A153 PolarHBondContact O-N 3.38Å; L151-A153 VanDerWaalsContact C-N 3.27Å; L151-A153 PolarHBondContact O-N 3.2Å; A153-G156 PolarHBondContact O-N 3.17Å; A153-L157 PolarHBondContact O-N 2.97Å
154	F	88.8	Confident	87.1	Confident	49 Å²	49	66.7 Å²	66.7	22%	0.215	35%	0.349	C	S	.	.	H	α-helix	trans	-68.7	-39.5	175.1	-175.2	-104.6	0	0	0	112.1	F139 L143 K150 L151 G156 L157 L158 M333	F139-F154 HydrophobicContact CE1-CZ 4.19Å; L143-F154 HydrophobicContact CD1-CD1 4.2Å; L143-F154 HydrophobicContact CD1-CE1 4.01Å; L143-F154 HydrophobicContact CD1-CE2 4.41Å; L143-F154 HydrophobicContact CD1-CG 4.46Å; L143-F154 HydrophobicContact CD1-CZ 4.13Å; K150-F154 PolarHBondContact O-N 3.46Å; L151-F154 PolarHBondContact O-N 2.88Å; L151-F154 VanDerWaalsContact O-N 3.11Å; F154-G156 VanDerWaalsContact C-N 3.34Å; F154-G156 PolarHBondContact O-N 3.39Å; F154-L157 HydrophobicContact CD2-CD2 4.45Å; F154-L157 WeakPolarHBondContact O-CB 3.45Å; F154-L157 PolarHBondContact O-N 2.93Å; F154-L158 HydrophobicContact CD1-CD1 4.02Å; F154-L158 HydrophobicContact CD1-CG 4.39Å; F154-L158 HydrophobicContact CE1-CD1 3.61Å; F154-L158 HydrophobicContact CE1-CD2 4.47Å; F154-L158 HydrophobicContact CE1-CG 4.1Å; F154-L158 HydrophobicContact CZ-CD1 4.19Å; F154-L158 HydrophobicContact CZ-CD2 4.24Å; F154-L158 HydrophobicContact CZ-CG 4.3Å; F154-L158 PolarHBondContact O-N 3.18Å; F154-M333 HydrophobicContact CD1-CE 3.64Å; F154-M333 HydrophobicContact CD1-SD 3.63Å; F154-M333 HydrophobicContact CE1-CE 4.08Å; F154-M333 HydrophobicContact CE1-SD 3.7Å
155	F	86.3	Confident	88	Confident	40 Å²	40	66.4 Å²	66.4	18%	0.175	35%	0.348	C	S	.	.	H	α-helix	trans	-57.9	-45.8	168.5	-78	-51.7	0	0	0	111.9	L151 E152 L157 L158 I159 S330 M333 T334	L151-F155 HydrophobicContact CD2-CD2 3.71Å; L151-F155 HydrophobicContact CD2-CE2 3.25Å; L151-F155 HydrophobicContact CD2-CZ 3.92Å; L151-F155 WeakPolarHBondContact O-CD2 3.34Å; L151-F155 PolarHBondContact O-N 2.67Å; E152-F155 PolarHBondContact O-N 2.93Å; F155-L157 VanDerWaalsContact C-N 3.26Å; F155-L157 PolarHBondContact O-N 3.47Å; F155-L158 PolarHBondContact O-N 3.46Å; F155-I159 WeakPolarHBondContact O-CB 3.38Å; F155-I159 WeakPolarHBondContact O-CG1 3.35Å; F155-I159 PolarHBondContact O-N 2.9Å; F155-S330 WeakPolarHBondContact CE1-O 3.32Å; F155-M333 HydrophobicContact CD1-SD 4.14Å; F155-M333 HydrophobicContact CE1-CB 3.51Å; F155-M333 HydrophobicContact CE1-CG 4.15Å; F155-M333 HydrophobicContact CE1-SD 3.72Å; F155-M333 HydrophobicContact CZ-CB 3.4Å; F155-M333 VanDerWaalsContact CZ-CB 3.4Å; F155-M333 HydrophobicContact CZ-CG 4.38Å; F155-M333 HydrophobicContact CZ-SD 4.19Å; F155-T334 HydrophobicContact CE1-CG2 4.07Å; F155-T334 HydrophobicContact CZ-CG2 3.93Å
156	G	89.8	Confident	88.7	Confident	33 Å²	33	62.6 Å²	62.6	34%	0.34	33%	0.327	S	S	.	.	H	α-helix	trans	-57.1	-38.8	175.3	0	0	0	0	0	112.8	E152 A153 F154 T160	E152-G156 PolarHBondContact O-N 3.16Å; A153-G156 PolarHBondContact O-N 3.17Å; F154-G156 VanDerWaalsContact C-N 3.34Å; F154-G156 PolarHBondContact O-N 3.39Å; G156-T160 WeakPolarHBondContact O-CB 3.27Å; G156-T160 PolarHBondContact O-N 3.45Å; G156-T160 PolarHBondContact O-OG1 3.29Å
157	L	93.4	Very high	89.4	Confident	95 Å²	95	57.6 Å²	57.6	50%	0.497	31%	0.312	S	S	.	.	H	α-helix	trans	-64.6	-49.3	174.1	178.5	64.6	0	0	0	112.1	A153 F154 F155 I159 T160 I161	A153-L157 PolarHBondContact O-N 2.97Å; F154-L157 HydrophobicContact CD2-CD2 4.45Å; F154-L157 WeakPolarHBondContact O-CB 3.45Å; F154-L157 PolarHBondContact O-N 2.93Å; F155-L157 VanDerWaalsContact C-N 3.26Å; F155-L157 PolarHBondContact O-N 3.47Å; L157-I159 PolarHBondContact O-N 3.19Å; L157-T160 WeakPolarHBondContact O-CB 3.4Å; L157-T160 PolarHBondContact O-N 3.42Å; L157-I161 HydrophobicContact CD1-CD1 4.35Å; L157-I161 HydrophobicContact CG-CD1 4.15Å; L157-I161 WeakPolarHBondContact O-CG1 3.4Å; L157-I161 PolarHBondContact O-N 2.93Å
158	L	92.8	Very high	90	Very high	11 Å²	11	61.2 Å²	61.2	6%	0.058	32%	0.316	C	S	.	.	H	α-helix	trans	-61.8	-43.1	179	-66.5	179	0	0	0	112.1	F154 F155 T160 I161 M162 A326 Q329 M333	F154-L158 HydrophobicContact CD1-CD1 4.02Å; F154-L158 HydrophobicContact CD1-CG 4.39Å; F154-L158 HydrophobicContact CE1-CD1 3.61Å; F154-L158 HydrophobicContact CE1-CD2 4.47Å; F154-L158 HydrophobicContact CE1-CG 4.1Å; F154-L158 HydrophobicContact CZ-CD1 4.19Å; F154-L158 HydrophobicContact CZ-CD2 4.24Å; F154-L158 HydrophobicContact CZ-CG 4.3Å; F154-L158 PolarHBondContact O-N 3.18Å; F155-L158 PolarHBondContact O-N 3.46Å; L158-T160 VanDerWaalsContact C-N 3.32Å; L158-T160 PolarHBondContact O-N 2.78Å; L158-I161 PolarHBondContact O-N 3.45Å; L158-M162 WeakPolarHBondContact O-CG 3.34Å; L158-M162 PolarHBondContact O-N 2.9Å; L158-A326 HydrophobicContact CD2-CB 4.14Å; L158-Q329 HydrophobicContact CD1-CB 3.85Å; L158-Q329 HydrophobicContact CD2-CB 4.26Å; L158-M333 HydrophobicContact CD1-SD 4.41Å
159	I	91.9	Very high	90.7	Very high	63 Å²	63	58.5 Å²	58.5	32%	0.323	30%	0.302	S	S	.	.	H	α-helix	trans	-63.4	-38.8	175.3	-65.7	166.6	0	0	0	111.1	F155 L157 M162 A163 V250 I254	F155-I159 WeakPolarHBondContact O-CB 3.38Å; F155-I159 WeakPolarHBondContact O-CG1 3.35Å; F155-I159 PolarHBondContact O-N 2.9Å; L157-I159 PolarHBondContact O-N 3.19Å; I159-M162 HydrophobicContact CB-CE 4.27Å; I159-M162 HydrophobicContact CG1-CE 3.82Å; I159-M162 PolarHBondContact O-N 3.49Å; I159-A163 WeakPolarHBondContact O-CB 3.39Å; I159-A163 PolarHBondContact O-N 3.48Å; I159-V250 HydrophobicContact CG2-CG1 3.72Å; I159-I254 HydrophobicContact CG2-CD1 4.38Å
160	T	94.4	Very high	91.3	Very high	74 Å²	74	50 Å²	50	45%	0.454	27%	0.27	S	S	.	.	H	α-helix	trans	-64.7	-41	174.8	-58.1	0	0	0	0	111.5	G156 L157 L158 A163 L164	G156-T160 WeakPolarHBondContact O-CB 3.27Å; G156-T160 PolarHBondContact O-N 3.45Å; G156-T160 PolarHBondContact O-OG1 3.29Å; L157-T160 WeakPolarHBondContact O-CB 3.4Å; L157-T160 PolarHBondContact O-N 3.42Å; L158-T160 VanDerWaalsContact C-N 3.32Å; L158-T160 PolarHBondContact O-N 2.78Å; T160-A163 PolarHBondContact O-N 2.72Å; T160-L164 HydrophobicContact CG2-CD1 3.98Å; T160-L164 HydrophobicContact CG2-CG 4.41Å; T160-L164 WeakPolarHBondContact O-CB 3.3Å; T160-L164 VanDerWaalsContact O-CG 3.28Å; T160-L164 WeakPolarHBondContact O-CG 3.44Å; T160-L164 PolarHBondContact O-N 3.26Å
161	I	95.6	Very high	91.6	Very high	50 Å²	50	48 Å²	48	26%	0.256	27%	0.268	S	S	.	.	H	α-helix	trans	-60	-51.8	174.7	-68.1	164.3	0	0	0	109.9	L157 L158 A163 L164 T165 V322 A326	L157-I161 HydrophobicContact CD1-CD1 4.35Å; L157-I161 HydrophobicContact CG-CD1 4.15Å; L157-I161 WeakPolarHBondContact O-CG1 3.4Å; L157-I161 PolarHBondContact O-N 2.93Å; L158-I161 PolarHBondContact O-N 3.45Å; I161-A163 VanDerWaalsContact C-N 3.34Å; I161-A163 PolarHBondContact O-N 3.49Å; I161-L164 PolarHBondContact O-N 3.47Å; I161-L164 VanDerWaalsContact O-N 3.16Å; I161-T165 HydrophobicContact CG2-CG2 4.15Å; I161-T165 WeakPolarHBondContact O-CG2 3.49Å; I161-T165 PolarHBondContact O-N 3Å; I161-T165 PolarHBondContact O-OG1 3.41Å; I161-T165 VanDerWaalsContact O-OG1 3.11Å; I161-V322 HydrophobicContact CG2-CG1 3.88Å; I161-A326 HydrophobicContact CB-CB 4.14Å; I161-A326 HydrophobicContact CG2-CB 3.76Å
162	M	93.8	Very high	92.1	Very high	23 Å²	23	49.6 Å²	49.6	11%	0.113	28%	0.278	C	S	.	.	H	α-helix	trans	-56	-45.4	177	-69.8	-171.4	-71.6	0	0	112.7	L158 I159 L164 T165 F166 I254 A326 A327	L158-M162 WeakPolarHBondContact O-CG 3.34Å; L158-M162 PolarHBondContact O-N 2.9Å; I159-M162 HydrophobicContact CB-CE 4.27Å; I159-M162 HydrophobicContact CG1-CE 3.82Å; I159-M162 PolarHBondContact O-N 3.49Å; M162-L164 VanDerWaalsContact C-N 3.32Å; M162-L164 PolarHBondContact O-N 3.33Å; M162-T165 PolarHBondContact O-N 3.18Å; M162-T165 PolarHBondContact O-OG1 3.06Å; M162-F166 HydrophobicContact CB-CD2 4.03Å; M162-F166 HydrophobicContact CB-CE2 3.96Å; M162-F166 HydrophobicContact CG-CE2 4.08Å; M162-F166 WeakPolarHBondContact O-CB 3.35Å; M162-F166 WeakPolarHBondContact O-CD2 3.34Å; M162-F166 WeakPolarHBondContact O-CG 3.48Å; M162-F166 PolarHBondContact O-N 2.88Å; M162-I254 HydrophobicContact CB-CD1 4.07Å; M162-A326 HydrophobicContact CG-CB 4Å; M162-A327 HydrophobicContact CG-CB 4.41Å; M162-A327 WeakPolarHBondContact SD-CA 3.35Å; M162-A327 HydrophobicContact SD-CB 3.53Å; M162-A327 VanDerWaalsContact SD-CB 3.53Å
163	A	94.4	Very high	92.2	Very high	33 Å²	33	46.8 Å²	46.8	27%	0.273	27%	0.266	S	S	.	.	H	α-helix	trans	-62.6	-38.4	178.9	0	0	0	0	0	112.5	I159 T160 I161 G167 I254	I159-A163 WeakPolarHBondContact O-CB 3.39Å; I159-A163 PolarHBondContact O-N 3.48Å; T160-A163 PolarHBondContact O-N 2.72Å; I161-A163 VanDerWaalsContact C-N 3.34Å; I161-A163 PolarHBondContact O-N 3.49Å; A163-G167 WeakPolarHBondContact O-CA 3.19Å; A163-G167 PolarHBondContact O-N 3.09Å; A163-I254 HydrophobicContact CB-CD1 4.19Å; A163-I254 HydrophobicContact CB-CG1 4.25Å
164	L	95.7	Very high	92.2	Very high	123 Å²	123	50.8 Å²	50.8	64%	0.644	27%	0.273	S	S	*	.	H	α-helix	trans	-74.5	-42.5	177.4	-69.7	173.4	0	0	0	112.4	T160 I161 M162 Y168	T160-L164 HydrophobicContact CG2-CD1 3.98Å; T160-L164 HydrophobicContact CG2-CG 4.41Å; T160-L164 WeakPolarHBondContact O-CB 3.3Å; T160-L164 VanDerWaalsContact O-CG 3.28Å; T160-L164 WeakPolarHBondContact O-CG 3.44Å; T160-L164 PolarHBondContact O-N 3.26Å; I161-L164 PolarHBondContact O-N 3.47Å; I161-L164 VanDerWaalsContact O-N 3.16Å; M162-L164 VanDerWaalsContact C-N 3.32Å; M162-L164 PolarHBondContact O-N 3.33Å; L164-Y168 WeakPolarHBondContact O-CB 3.4Å; L164-Y168 PolarHBondContact O-N 2.95Å
165	T	95	Very high	91.9	Very high	15 Å²	15	48.8 Å²	48.8	9%	0.092	27%	0.265	C	S	.	.	H	α-helix	trans	-68.7	-52.5	-179.4	54.8	0	0	0	0	111.3	I161 M162 G167 Y168 E169 I319 V322 G323	I161-T165 HydrophobicContact CG2-CG2 4.15Å; I161-T165 WeakPolarHBondContact O-CG2 3.49Å; I161-T165 PolarHBondContact O-N 3Å; I161-T165 PolarHBondContact O-OG1 3.41Å; I161-T165 VanDerWaalsContact O-OG1 3.11Å; M162-T165 PolarHBondContact O-N 3.18Å; M162-T165 PolarHBondContact O-OG1 3.06Å; T165-G167 VanDerWaalsContact C-N 3.32Å; T165-G167 PolarHBondContact O-N 3.45Å; T165-Y168 WeakPolarHBondContact O-CB 3.4Å; T165-Y168 PolarHBondContact O-N 2.85Å; T165-E169 PolarHBondContact O-N 3.08Å; T165-E169 VanDerWaalsContact O-N 3.13Å; T165-I319 WeakPolarHBondContact CB-O 3.32Å; T165-I319 HydrophobicContact CG2-CG2 3.98Å; T165-V322 HydrophobicContact CG2-CB 4.4Å; T165-V322 HydrophobicContact CG2-CG1 4.16Å; T165-G323 WeakPolarHBondContact OG1-CA 3.05Å
166	F	93.4	Very high	91.9	Very high	13 Å²	13	50.2 Å²	50.2	6%	0.057	28%	0.28	C	S	.	.	H	α-helix	trans	-72.9	-27.5	-180	-56.8	-51.1	0	0	0	112.1	M162 Y170 I254 F257 V258 W320	M162-F166 HydrophobicContact CB-CD2 4.03Å; M162-F166 HydrophobicContact CB-CE2 3.96Å; M162-F166 HydrophobicContact CG-CE2 4.08Å; M162-F166 WeakPolarHBondContact O-CB 3.35Å; M162-F166 WeakPolarHBondContact O-CD2 3.34Å; M162-F166 WeakPolarHBondContact O-CG 3.48Å; M162-F166 PolarHBondContact O-N 2.88Å; F166-Y170 WeakPolarHBondContact O-CB 3.33Å; F166-Y170 PolarHBondContact O-N 3.45Å; F166-I254 HydrophobicContact CD2-CG2 3.71Å; F166-I254 HydrophobicContact CE2-CG2 4.27Å; F166-F257 HydrophobicContact CB-CB 4.41Å; F166-V258 HydrophobicContact CB-CG2 4.14Å; F166-V258 HydrophobicContact CD1-CG2 3.87Å; F166-V258 HydrophobicContact CD2-CG2 4.1Å; F166-V258 HydrophobicContact CE1-CG2 4.27Å; F166-V258 HydrophobicContact CE2-CG2 4.47Å; F166-V258 HydrophobicContact CG-CG2 3.78Å; F166-W320 AromaticContact CD1-CE3 3.92Å; F166-W320 HydrophobicContact CD1-CE3 3.92Å; F166-W320 AromaticContact CD1-CZ3 3.79Å; F166-W320 HydrophobicContact CD1-CZ3 3.79Å; F166-W320 HydrophobicContact CE1-CD2 4.3Å; F166-W320 AromaticContact CE1-CE3 3.68Å; F166-W320 HydrophobicContact CE1-CE3 3.68Å; F166-W320 HydrophobicContact CE1-CH2 4.17Å; F166-W320 AromaticContact CE1-CZ3 3.61Å; F166-W320 HydrophobicContact CE1-CZ3 3.61Å
167	G	94.4	Very high	91.6	Very high	13 Å²	13	53.4 Å²	53.4	13%	0.134	29%	0.286	C	S	.	.	H	α-helix	trans	-66.1	-37	169.4	0	0	0	0	0	113.2	A163 T165 Y170 V171	A163-G167 WeakPolarHBondContact O-CA 3.19Å; A163-G167 PolarHBondContact O-N 3.09Å; T165-G167 VanDerWaalsContact C-N 3.32Å; T165-G167 PolarHBondContact O-N 3.45Å; G167-Y170 PolarHBondContact O-N 3.39Å; G167-V171 WeakPolarHBondContact O-CG2 3.16Å; G167-V171 PolarHBondContact O-N 3.21Å; G167-V171 VanDerWaalsContact O-N 3.07Å
168	Y	94.9	Very high	91.1	Very high	110 Å²	110	51.1 Å²	51.1	43%	0.431	29%	0.286	S	S	.	.	H	α-helix	trans	-63.6	-50.1	172.4	177.8	-91.5	0	0	0	111.3	L164 T165 Y170 V171 V172 I319	L164-Y168 WeakPolarHBondContact O-CB 3.4Å; L164-Y168 PolarHBondContact O-N 2.95Å; T165-Y168 WeakPolarHBondContact O-CB 3.4Å; T165-Y168 PolarHBondContact O-N 2.85Å; Y168-Y170 VanDerWaalsContact C-N 3.27Å; Y168-Y170 PolarHBondContact O-N 3.23Å; Y168-V171 PolarHBondContact O-N 3.04Å; Y168-V171 VanDerWaalsContact O-N 3.12Å; Y168-V172 HydrophobicContact CD1-CG2 4.07Å; Y168-V172 HydrophobicContact CD2-CG2 4.4Å; Y168-V172 HydrophobicContact CE1-CG2 3.65Å; Y168-V172 HydrophobicContact CE2-CG2 4Å; Y168-V172 HydrophobicContact CG-CG2 4.44Å; Y168-V172 WeakPolarHBondContact O-CG2 3.48Å; Y168-V172 PolarHBondContact O-N 3.32Å; Y168-I319 HydrophobicContact CD1-CD1 3.48Å; Y168-I319 VanDerWaalsContact CD1-CD1 3.48Å; Y168-I319 HydrophobicContact CD1-CG2 4.04Å; Y168-I319 HydrophobicContact CE1-CD1 3.38Å; Y168-I319 HydrophobicContact CG-CD1 4.14Å
169	E	91.5	Very high	90.4	Very high	1 Å²	1	51.8 Å²	51.8	1%	0.005	29%	0.293	C	S	.	.	H	α-helix	trans	-55	-43.3	175.7	-64.9	-53.9	129.6	0	0	111.7	T165 V171 V172 A173 V261 A316 I319	T165-E169 PolarHBondContact O-N 3.08Å; T165-E169 VanDerWaalsContact O-N 3.13Å; E169-V171 PolarHBondContact O-N 3.25Å; E169-V172 PolarHBondContact O-N 3.24Å; E169-A173 VanDerWaalsContact O-CB 3.23Å; E169-A173 WeakPolarHBondContact O-CB 3.43Å; E169-A173 PolarHBondContact O-N 2.84Å; E169-V261 HydrophobicContact CB-CG1 4.24Å; E169-V261 HydrophobicContact CB-CG2 3.99Å; E169-A316 VanDerWaalsContact OE1-CA 3.25Å; E169-A316 WeakPolarHBondContact OE1-CA 3.46Å; E169-A316 WeakPolarHBondContact OE2-CB 3.47Å; E169-I319 HydrophobicContact CG-CG2 4.49Å; E169-I319 WeakPolarHBondContact OE1-CG2 3.36Å
170	Y	92.4	Very high	89.9	Confident	31 Å²	31	49.5 Å²	49.5	12%	0.122	28%	0.282	C	S	.	.	H	α-helix	trans	-62.1	-41.6	177.4	-178.7	-96.9	0	0	0	113.3	F166 G167 Y168 H174 P175 Q177 L180 F257 A260 V261	F166-Y170 WeakPolarHBondContact O-CB 3.33Å; F166-Y170 PolarHBondContact O-N 3.45Å; G167-Y170 PolarHBondContact O-N 3.39Å; Y168-Y170 VanDerWaalsContact C-N 3.27Å; Y168-Y170 PolarHBondContact O-N 3.23Å; Y170-H174 PolarHBondContact O-N 3.15Å; Y170-P175 HydrophobicContact CD2-CG 3.73Å; Y170-P175 HydrophobicContact CE2-CG 3.44Å; Y170-P175 VanDerWaalsContact CE2-CG 3.44Å; Y170-P175 HydrophobicContact CG-CG 4.47Å; Y170-P175 WeakPolarHBondContact O-CD 3.49Å; Y170-Q177 VanDerWaalsContact OH-CD 3.27Å; Y170-Q177 PolarHBondContact OH-NE2 3.07Å; Y170-Q177 PolarHBondContact OH-OE1 3.06Å; Y170-L180 HydrophobicContact CE2-CD1 3.87Å; Y170-L180 WeakPolarHBondContact OH-CD1 3.37Å; Y170-F257 AromaticContact CD1-CD1 3.72Å; Y170-F257 HydrophobicContact CD1-CD1 3.72Å; Y170-F257 AromaticContact CD1-CE1 3.65Å; Y170-F257 HydrophobicContact CD1-CE1 3.65Å; Y170-F257 HydrophobicContact CD1-CZ 4.4Å; Y170-F257 HydrophobicContact CD2-CB 4.2Å; Y170-F257 AromaticContact CD2-CD1 3.5Å; Y170-F257 HydrophobicContact CD2-CD1 3.5Å; Y170-F257 HydrophobicContact CD2-CE1 4.24Å; Y170-F257 HydrophobicContact CD2-CG 4.15Å; Y170-F257 HydrophobicContact CE1-CD1 4.11Å; Y170-F257 AromaticContact CE1-CE1 3.86Å; Y170-F257 HydrophobicContact CE1-CE1 3.86Å; Y170-F257 AromaticContact CE2-CD1 3.88Å; Y170-F257 HydrophobicContact CE2-CD1 3.88Å; Y170-F257 HydrophobicContact CE2-CE1 4.4Å; Y170-F257 HydrophobicContact CG-CB 4.28Å; Y170-F257 AromaticContact CG-CD1 3.39Å; Y170-F257 HydrophobicContact CG-CD1 3.39Å; Y170-F257 AromaticContact CG-CE1 3.84Å; Y170-F257 HydrophobicContact CG-CE1 3.84Å; Y170-F257 AromaticContact CG-CG 3.93Å; Y170-F257 HydrophobicContact CG-CG 3.93Å; Y170-A260 HydrophobicContact CD2-CB 3.88Å; Y170-A260 HydrophobicContact CE2-CB 3.63Å; Y170-V261 VanDerWaalsContact CA-CG2 3.47Å
171	V	92.9	Very high	89.4	Confident	91 Å²	91	51.6 Å²	51.6	55%	0.552	29%	0.289	S	S	*	.	H	α-helix	trans	-67.4	-44.2	177	171.2	0	0	0	0	110.7	G167 Y168 E169 H174	G167-V171 WeakPolarHBondContact O-CG2 3.16Å; G167-V171 PolarHBondContact O-N 3.21Å; G167-V171 VanDerWaalsContact O-N 3.07Å; Y168-V171 PolarHBondContact O-N 3.04Å; Y168-V171 VanDerWaalsContact O-N 3.12Å; E169-V171 PolarHBondContact O-N 3.25Å; V171-H174 PolarHBondContact O-CD2 3.25Å; V171-H174 PolarHBondContact O-CE1 3.48Å; V171-H174 PolarHBondContact O-N 3.12Å; V171-H174 PolarHBondContact O-ND1 2.98Å; V171-H174 PolarHBondContact O-NE2 3.36Å
172	V	91	Very high	88.8	Confident	41 Å²	41	55.9 Å²	55.9	25%	0.248	31%	0.306	C	S	.	.	H	α-helix	trans	-69.6	-38.2	-178.2	173.9	0	0	0	0	112.4	Y168 E169 H174 F312	Y168-V172 HydrophobicContact CD1-CG2 4.07Å; Y168-V172 HydrophobicContact CD2-CG2 4.4Å; Y168-V172 HydrophobicContact CE1-CG2 3.65Å; Y168-V172 HydrophobicContact CE2-CG2 4Å; Y168-V172 HydrophobicContact CG-CG2 4.44Å; Y168-V172 WeakPolarHBondContact O-CG2 3.48Å; Y168-V172 PolarHBondContact O-N 3.32Å; E169-V172 PolarHBondContact O-N 3.24Å; V172-H174 PolarHBondContact O-CD2 2.89Å; V172-H174 PolarHBondContact O-N 3.17Å; V172-F312 HydrophobicContact CG1-CB 3.76Å; V172-F312 HydrophobicContact CG1-CD1 3.85Å; V172-F312 HydrophobicContact CG1-CG 3.87Å
173	A	86.7	Confident	88	Confident	7 Å²	7	55 Å²	55	6%	0.058	30%	0.302	C	S	.	.	H	α-helix	trans	-69.3	-16.7	178.1	0	0	0	0	0	113.8	E169 P175 V261 F312	E169-A173 VanDerWaalsContact O-CB 3.23Å; E169-A173 WeakPolarHBondContact O-CB 3.43Å; E169-A173 PolarHBondContact O-N 2.84Å; A173-P175 VanDerWaalsContact C-CD 3.5Å; A173-V261 HydrophobicContact CB-CG2 4.15Å; A173-F312 HydrophobicContact CB-CE2 3.98Å; A173-F312 HydrophobicContact CB-CZ 3.8Å
174	H	86.4	Confident	87.5	Confident	150 Å²	150	54.9 Å²	54.9	69%	0.694	30%	0.297	S	S	*	.			trans	42.8	51.1	-178.8	-70.8	-67.6	0	0	0	114.8	Y170 V171 V172	Y170-H174 PolarHBondContact O-N 3.15Å; V171-H174 PolarHBondContact O-CD2 3.25Å; V171-H174 PolarHBondContact O-CE1 3.48Å; V171-H174 PolarHBondContact O-N 3.12Å; V171-H174 PolarHBondContact O-ND1 2.98Å; V171-H174 PolarHBondContact O-NE2 3.36Å; V172-H174 PolarHBondContact O-CD2 2.89Å; V172-H174 PolarHBondContact O-N 3.17Å
175	P	83.9	Confident	86.7	Confident	7 Å²	7	54 Å²	54	5%	0.045	30%	0.297	C	S	.	.			trans	-65.6	151.7	-176.2	29.5	-35.4	0	0	0	111.8	Y170 A173 Q177 L180 A260 Q264	Y170-P175 HydrophobicContact CD2-CG 3.73Å; Y170-P175 HydrophobicContact CE2-CG 3.44Å; Y170-P175 VanDerWaalsContact CE2-CG 3.44Å; Y170-P175 HydrophobicContact CG-CG 4.47Å; Y170-P175 WeakPolarHBondContact O-CD 3.49Å; A173-P175 VanDerWaalsContact C-CD 3.5Å; P175-Q177 PolarHBondContact O-N 3.5Å; P175-Q177 PolarHBondContact O-NE2 2.98Å; P175-L180 HydrophobicContact CB-CD1 4.12Å; P175-L180 HydrophobicContact CG-CD1 4.06Å; P175-A260 HydrophobicContact CB-CB 4.35Å; P175-A260 HydrophobicContact CG-CB 4.18Å; P175-Q264 HydrophobicContact CB-CB 4.3Å
176	S	84.8	Confident	85.8	Confident	70 Å²	70	57.6 Å²	57.6	49%	0.49	32%	0.315	S	S	.	.			trans	-70.6	100.1	-173.8	66.1	0	0	0	0	112.9	G178 A179 L180	S176-G178 PolarHBondContact O-N 3.33Å; S176-G178 VanDerWaalsContact O-N 3.09Å; S176-A179 PolarHBondContact O-N 3.24Å; S176-A179 VanDerWaalsContact OG-CB 3.29Å; S176-A179 WeakPolarHBondContact OG-CB 3.23Å; S176-L180 PolarHBondContact O-N 2.91Å
177	Q	84.8	Confident	84.8	Confident	100 Å²	100	61.3 Å²	61.3	47%	0.467	34%	0.34	S	S	.	.	H	α-helix	trans	-54.3	-35.9	-174.5	-55.6	-59	-67.7	0	0	113.5	Y170 P175 A179 L180 L181	Y170-Q177 VanDerWaalsContact OH-CD 3.27Å; Y170-Q177 PolarHBondContact OH-NE2 3.07Å; Y170-Q177 PolarHBondContact OH-OE1 3.06Å; P175-Q177 PolarHBondContact O-N 3.5Å; P175-Q177 PolarHBondContact O-NE2 2.98Å; Q177-A179 VanDerWaalsContact C-N 3.35Å; Q177-A179 PolarHBondContact O-N 3.26Å; Q177-L180 PolarHBondContact O-N 3.5Å; Q177-L181 WeakPolarHBondContact O-CB 3.34Å; Q177-L181 PolarHBondContact O-N 2.68Å
178	G	82.2	Confident	83.4	Confident	47 Å²	47	64.5 Å²	64.5	49%	0.485	36%	0.357	S	S	.	.	H	α-helix	trans	-71.2	-22.9	178.4	0	0	0	0	0	114.8	S176 K182	S176-G178 PolarHBondContact O-N 3.33Å; S176-G178 VanDerWaalsContact O-N 3.09Å; G178-K182 WeakPolarHBondContact O-CD 3.34Å; G178-K182 VanDerWaalsContact O-CG 3.28Å; G178-K182 WeakPolarHBondContact O-CG 3.5Å
179	A	77.8	Confident	82	Confident	26 Å²	26	61.1 Å²	61.1	22%	0.215	35%	0.349	C	S	.	.	H	α-helix	trans	-80.8	-45.5	171	0	0	0	0	0	110.4	S176 Q177 L181 K182 G183	S176-A179 PolarHBondContact O-N 3.24Å; S176-A179 VanDerWaalsContact OG-CB 3.29Å; S176-A179 WeakPolarHBondContact OG-CB 3.23Å; Q177-A179 VanDerWaalsContact C-N 3.35Å; Q177-A179 PolarHBondContact O-N 3.26Å; A179-L181 PolarHBondContact O-N 2.76Å; A179-K182 WeakPolarHBondContact O-CB 3.39Å; A179-K182 PolarHBondContact O-N 3.49Å; A179-K182 VanDerWaalsContact O-N 3.08Å; A179-G183 PolarHBondContact O-N 3.15Å
180	L	82.2	Confident	80.1	Confident	15 Å²	15	66 Å²	66	8%	0.079	38%	0.381	C	S	.	.	H	α-helix	trans	-55.7	-47.7	177.3	-63.5	176.2	0	0	0	112.4	L49 Y170 P175 S176 Q177 K182 G183 L184 A260	L49-L180 HydrophobicContact CD1-CD2 3.69Å; Y170-L180 HydrophobicContact CE2-CD1 3.87Å; Y170-L180 WeakPolarHBondContact OH-CD1 3.37Å; P175-L180 HydrophobicContact CB-CD1 4.12Å; P175-L180 HydrophobicContact CG-CD1 4.06Å; S176-L180 PolarHBondContact O-N 2.91Å; Q177-L180 PolarHBondContact O-N 3.5Å; L180-K182 VanDerWaalsContact C-N 3.3Å; L180-K182 PolarHBondContact O-N 3.05Å; L180-G183 PolarHBondContact O-N 2.95Å; L180-L184 WeakPolarHBondContact O-CB 3.19Å; L180-L184 PolarHBondContact O-N 3.45Å; L180-A260 HydrophobicContact CD1-CB 3.86Å; L180-A260 HydrophobicContact CD2-CB 3.62Å; L180-A260 HydrophobicContact CG-CB 4.41Å
181	L	84.3	Confident	78.4	Confident	117 Å²	117	67.8 Å²	67.8	61%	0.613	41%	0.408	S	S	*	.	H	α-helix	trans	-63	-34.4	177.4	-79.2	165.3	0	0	0	113.1	Q177 A179 V185	Q177-L181 WeakPolarHBondContact O-CB 3.34Å; Q177-L181 PolarHBondContact O-N 2.68Å; A179-L181 PolarHBondContact O-N 2.76Å; L181-V185 WeakPolarHBondContact O-CG2 3.22Å
182	K	81.8	Confident	76.9	Confident	141 Å²	141	67.2 Å²	67.2	61%	0.613	41%	0.408	S	S	*	.	H	α-helix	trans	-69.9	-48.9	174.4	-73.8	174.1	-174.4	179.1	0	110.8	G178 A179 L180 L184 V185 L186	G178-K182 WeakPolarHBondContact O-CD 3.34Å; G178-K182 VanDerWaalsContact O-CG 3.28Å; G178-K182 WeakPolarHBondContact O-CG 3.5Å; A179-K182 WeakPolarHBondContact O-CB 3.39Å; A179-K182 PolarHBondContact O-N 3.49Å; A179-K182 VanDerWaalsContact O-N 3.08Å; L180-K182 VanDerWaalsContact C-N 3.3Å; L180-K182 PolarHBondContact O-N 3.05Å; K182-L184 PolarHBondContact O-N 3.21Å; K182-V185 PolarHBondContact O-N 3.4Å; K182-V185 VanDerWaalsContact O-N 3.16Å; K182-L186 HydrophobicContact CB-CD1 4.27Å; K182-L186 HydrophobicContact CG-CD1 4.43Å; K182-L186 WeakPolarHBondContact O-CB 3.44Å; K182-L186 PolarHBondContact O-N 3.39Å
183	G	78.7	Confident	75.7	Confident	3 Å²	3	66.8 Å²	66.8	3%	0.031	41%	0.411	C	S	.	.	H	α-helix	trans	-62.3	-27.3	179.4	0	0	0	0	0	114.3	D46 W50 A179 L180	D46-G183 CarbonylContact O-C 3.51Å; D46-G183 WeakPolarHBondContact O-CA 3.29Å; W50-G183 PolarHBondContact N-O 2.75Å; A179-G183 PolarHBondContact O-N 3.15Å; L180-G183 PolarHBondContact O-N 2.95Å
184	L	82.8	Confident	74.8	Confident	31 Å²	31	70.6 Å²	70.6	16%	0.162	43%	0.428	C	S	.	.	H	α-helix	trans	-71.9	-35.9	175	-155.9	84.9	0	0	0	113.4	L49 L53 L180 K182 F252 L256	L49-L184 HydrophobicContact CB-CD1 4.45Å; L53-L184 HydrophobicContact CB-CD1 4.27Å; L53-L184 HydrophobicContact CB-CG 4.36Å; L53-L184 HydrophobicContact CD2-CD2 4.22Å; L53-L184 HydrophobicContact CD2-CG 4.09Å; L180-L184 WeakPolarHBondContact O-CB 3.19Å; L180-L184 PolarHBondContact O-N 3.45Å; K182-L184 PolarHBondContact O-N 3.21Å; L184-F252 HydrophobicContact CD1-CE2 4.11Å; L184-F252 HydrophobicContact CD1-CZ 3.71Å; L184-F252 HydrophobicContact CD2-CZ 4.23Å; L184-L256 HydrophobicContact CD1-CD1 4.39Å
185	V	79.1	Confident	73.9	Confident	105 Å²	105	65.6 Å²	65.6	64%	0.636	41%	0.409	S	S	*	.	H	α-helix	trans	-103.2	-32.7	-168.9	178.8	0	0	0	0	112.8	L181 K182 P187	L181-V185 WeakPolarHBondContact O-CG2 3.22Å; K182-V185 PolarHBondContact O-N 3.4Å; K182-V185 VanDerWaalsContact O-N 3.16Å; V185-P187 WeakPolarHBondContact O-CD 3.25Å
186	L	76.8	Confident	73.4	Confident	90 Å²	90	66.7 Å²	66.7	47%	0.471	41%	0.413	S	S	.	.			trans	-99.3	112	-175.1	-68.6	165.2	0	0	0	110.7	K182 T188	K182-L186 HydrophobicContact CB-CD1 4.27Å; K182-L186 HydrophobicContact CG-CD1 4.43Å; K182-L186 WeakPolarHBondContact O-CB 3.44Å; K182-L186 PolarHBondContact O-N 3.39Å; L186-T188 HydrophobicContact CB-CG2 4.29Å; L186-T188 PolarHBondContact O-N 3.42Å
187	P	71.9	Confident	72.8	Confident	91 Å²	91	66.5 Å²	66.5	59%	0.591	41%	0.406	S	S	*	.			trans	-76.1	76.3	173.1	32.3	-34.9	0	0	0	110.2	W50 V185	W50-P187 HydrophobicContact CD2-CB 3.82Å; W50-P187 HydrophobicContact CE3-CB 4.11Å; W50-P187 HydrophobicContact CG-CB 4.12Å; V185-P187 WeakPolarHBondContact O-CD 3.25Å
188	T	65.5	Low	72.2	Confident	81 Å²	81	64.7 Å²	64.7	50%	0.497	40%	0.4	S	S	.	.			trans	-110.2	112.1	176.7	51.5	0	0	0	0	110.8	L186 P190	L186-T188 HydrophobicContact CB-CG2 4.29Å; L186-T188 PolarHBondContact O-N 3.42Å; T188-P190 WeakPolarHBondContact O-CD 3.46Å
189	C	64.4	Low	71.8	Confident	38 Å²	38	66.2 Å²	66.2	26%	0.257	39%	0.394	S	S	.	.			trans	-121.1	83	173.1	-169.6	0	0	0	0	109.9	G191 C192	C189-G191 PolarHBondContact O-N 3.06Å; C189-C192 HydrophobicContact CB-CB 3.91Å; C189-C192 WeakPolarHBondContact CB-SG 3.28Å; C189-C192 WeakPolarHBondContact SG-CA 3.21Å; C189-C192 WeakPolarHBondContact SG-CB 3.48Å; C189-C192 CovalentContact SG-SG 2.03Å; C189-C192 PolarHBondContact SG-SG 3.2Å
190	P	52.6	Low	71.9	Confident	105 Å²	105	65.7 Å²	65.7	68%	0.682	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.2	90	179	30.5	-33.6	0	0	0	110.2	T188	T188-P190 WeakPolarHBondContact O-CD 3.46Å
191	G	55.6	Low	71.6	Confident	67 Å²	67	65.5 Å²	65.5	69%	0.691	39%	0.39	S	S	*	.	T	Hydrogen-bonded Turn	trans	110.8	21	178.3	0	0	0	0	0	115.9	C189 G193	C189-G191 PolarHBondContact O-N 3.06Å; G191-G193 PolarHBondContact O-N 3.03Å
192	C	62.3	Low	71.4	Confident	79 Å²	79	60.4 Å²	60.4	53%	0.534	37%	0.365	S	S	.	.			trans	-47.1	105.2	176.2	-105.6	0	0	0	0	113	C189	C189-C192 HydrophobicContact CB-CB 3.91Å; C189-C192 WeakPolarHBondContact CB-SG 3.28Å; C189-C192 WeakPolarHBondContact SG-CA 3.21Å; C189-C192 WeakPolarHBondContact SG-CB 3.48Å; C189-C192 CovalentContact SG-SG 2.03Å; C189-C192 PolarHBondContact SG-SG 3.2Å
193	G	65.8	Low	71.4	Confident	32 Å²	32	54.9 Å²	54.9	33%	0.33	34%	0.342	S	S	.	.			trans	-100.9	-161.4	173.1	0	0	0	0	0	112.1	G191 E196 L197	G191-G193 PolarHBondContact O-N 3.03Å; G193-E196 WeakPolarHBondContact CA-OE2 3.37Å; G193-E196 PolarHBondContact N-OE2 3.11Å; G193-L197 WeakPolarHBondContact O-CB 3.42Å
194	Q	66.8	Low	71.6	Confident	88 Å²	88	55.8 Å²	55.8	41%	0.411	35%	0.347	S	S	.	.	H	α-helix	trans	-63.2	-45.4	173.3	-67.5	-79.2	-15.8	0	0	113.5	L198 Y438 S442	Q194-L198 WeakPolarHBondContact O-CG 3.32Å; Q194-L198 PolarHBondContact O-N 2.82Å; Q194-Y438 PolarHBondContact NE2-OH 2.95Å; Q194-Y438 PolarHBondContact OE1-OH 3.34Å; Q194-S442 PolarHBondContact OE1-OG 2.94Å
195	P	67.9	Low	71.6	Confident	44 Å²	44	54.3 Å²	54.3	29%	0.286	34%	0.339	S	S	.	.	H	α-helix	trans	-73.4	-37.9	-173	27.9	-32.3	0	0	0	113.2	I40 L197 L198 Q199	I40-P195 HydrophobicContact CD1-CB 4.14Å; I40-P195 HydrophobicContact CG1-CB 4.03Å; I40-P195 HydrophobicContact CG2-CB 4.09Å; P195-L197 VanDerWaalsContact C-N 3.3Å; P195-L197 PolarHBondContact O-N 3.4Å; P195-L198 PolarHBondContact O-N 2.88Å; P195-Q199 PolarHBondContact O-N 3.38Å
196	E	72.6	Confident	71.8	Confident	30 Å²	30	51.3 Å²	51.3	14%	0.14	33%	0.325	C	S	.	.	H	α-helix	trans	-66.5	-35.6	177.5	-55.7	78	-171.5	0	0	111	P43 G193 Q199 A200	P43-E196 HydrophobicContact CB-CG 4.41Å; P43-E196 HydrophobicContact CG-CG 4.22Å; G193-E196 WeakPolarHBondContact CA-OE2 3.37Å; G193-E196 PolarHBondContact N-OE2 3.11Å; E196-Q199 PolarHBondContact O-N 2.96Å; E196-A200 WeakPolarHBondContact O-CB 3.3Å; E196-A200 PolarHBondContact O-N 3.27Å
197	L	73.3	Confident	72.3	Confident	66 Å²	66	48.2 Å²	48.2	35%	0.346	31%	0.309	S	S	.	.	H	α-helix	trans	-69.5	-40	174.1	-177.6	55.9	0	0	0	111.8	G193 P195 Q199 A200 V201 Y438	G193-L197 WeakPolarHBondContact O-CB 3.42Å; P195-L197 VanDerWaalsContact C-N 3.3Å; P195-L197 PolarHBondContact O-N 3.4Å; L197-Q199 VanDerWaalsContact C-N 3.32Å; L197-Q199 PolarHBondContact O-N 2.9Å; L197-A200 PolarHBondContact O-N 3.49Å; L197-V201 HydrophobicContact CD1-CG2 4.34Å; L197-V201 WeakPolarHBondContact O-CB 3.24Å; L197-V201 VanDerWaalsContact O-CG2 3.25Å; L197-V201 WeakPolarHBondContact O-CG2 3.13Å; L197-V201 PolarHBondContact O-N 3.39Å; L197-Y438 HydrophobicContact CD2-CD1 4.06Å; L197-Y438 HydrophobicContact CD2-CE1 3.37Å; L197-Y438 HydrophobicContact CD2-CE2 4.38Å; L197-Y438 HydrophobicContact CG-CE1 4.15Å
198	L	72.1	Confident	73.1	Confident	63 Å²	63	44.2 Å²	44.2	33%	0.33	28%	0.283	S	S	.	.	H	α-helix	trans	-60.4	-41.4	171.9	-76.8	165.9	0	0	0	111.6	Q194 P195 V201 G202 F439	Q194-L198 WeakPolarHBondContact O-CG 3.32Å; Q194-L198 PolarHBondContact O-N 2.82Å; P195-L198 PolarHBondContact O-N 2.88Å; L198-V201 PolarHBondContact O-N 2.87Å; L198-G202 PolarHBondContact O-N 3.04Å; L198-F439 HydrophobicContact CD2-CD2 3.71Å; L198-F439 HydrophobicContact CD2-CE2 3.59Å
199	Q	74.8	Confident	74.3	Confident	78 Å²	78	42.1 Å²	42.1	36%	0.364	27%	0.268	S	S	.	.	H	α-helix	trans	-64.2	-43.8	174.9	-167.5	179.3	14.3	0	0	111.9	L48 P195 E196 L197 V201 G202 I203	L48-Q199 HydrophobicContact CD1-CB 4.33Å; L48-Q199 VanDerWaalsContact CD1-CD 3.5Å; L48-Q199 HydrophobicContact CD1-CG 3.9Å; P195-Q199 PolarHBondContact O-N 3.38Å; E196-Q199 PolarHBondContact O-N 2.96Å; L197-Q199 VanDerWaalsContact C-N 3.32Å; L197-Q199 PolarHBondContact O-N 2.9Å; Q199-V201 VanDerWaalsContact C-N 3.33Å; Q199-V201 PolarHBondContact O-N 3.49Å; Q199-G202 PolarHBondContact O-N 2.98Å; Q199-I203 HydrophobicContact CG-CD1 4.47Å; Q199-I203 WeakPolarHBondContact O-CG1 3.09Å; Q199-I203 PolarHBondContact O-N 3.31Å
200	A	78.1	Confident	75.6	Confident	15 Å²	15	40.3 Å²	40.3	12%	0.124	26%	0.255	C	S	.	.	H	α-helix	trans	-60.8	-40.7	175	0	0	0	0	0	112.4	L48 V51 E196 L197 I203 V204	L48-A200 HydrophobicContact CD2-CB 4.01Å; V51-A200 HydrophobicContact CG1-CB 4.24Å; V51-A200 HydrophobicContact CG2-CB 4.25Å; E196-A200 WeakPolarHBondContact O-CB 3.3Å; E196-A200 PolarHBondContact O-N 3.27Å; L197-A200 PolarHBondContact O-N 3.49Å; A200-I203 PolarHBondContact O-N 3.07Å; A200-V204 WeakPolarHBondContact O-CG2 3.37Å; A200-V204 PolarHBondContact O-N 3Å
201	V	77	Confident	77.5	Confident	12 Å²	12	35.3 Å²	35.3	7%	0.073	22%	0.223	C	C	.	.	H	α-helix	trans	-66.2	-39	174.7	170.9	0	0	0	0	111.2	L197 L198 Q199 V204 G205 S392 I435	L197-V201 HydrophobicContact CD1-CG2 4.34Å; L197-V201 WeakPolarHBondContact O-CB 3.24Å; L197-V201 VanDerWaalsContact O-CG2 3.25Å; L197-V201 WeakPolarHBondContact O-CG2 3.13Å; L197-V201 PolarHBondContact O-N 3.39Å; L198-V201 PolarHBondContact O-N 2.87Å; Q199-V201 VanDerWaalsContact C-N 3.33Å; Q199-V201 PolarHBondContact O-N 3.49Å; V201-V204 PolarHBondContact O-N 3.16Å; V201-G205 PolarHBondContact O-N 3.48Å; V201-S392 VanDerWaalsContact CG1-OG 3.24Å; V201-S392 WeakPolarHBondContact CG1-OG 3.12Å; V201-S392 WeakPolarHBondContact O-CB 3.36Å; V201-S392 PolarHBondContact O-OG 3.36Å; V201-I435 HydrophobicContact CB-CG2 4.38Å; V201-I435 HydrophobicContact CG1-CG2 3.78Å; V201-I435 HydrophobicContact CG2-CG2 3.64Å
202	G	78.6	Confident	79.2	Confident	10 Å²	10	33.2 Å²	33.2	10%	0.103	20%	0.196	C	C	.	.	H	α-helix	trans	-60.3	-44.6	171.1	0	0	0	0	0	113.1	L198 Q199 V204 G205 A206	L198-G202 PolarHBondContact O-N 3.04Å; Q199-G202 PolarHBondContact O-N 2.98Å; G202-V204 VanDerWaalsContact C-N 3.34Å; G202-V204 PolarHBondContact O-N 2.84Å; G202-G205 PolarHBondContact O-N 2.81Å; G202-A206 WeakPolarHBondContact O-CB 3.47Å; G202-A206 PolarHBondContact O-N 2.89Å
203	I	82.6	Confident	80.6	Confident	24 Å²	24	29.6 Å²	29.6	12%	0.123	17%	0.171	C	C	.	.	H	α-helix	trans	-60.2	-42.3	175.1	-69.3	165.5	0	0	0	111.1	L48 V51 L52 Q199 A200 A206 I207	L48-I203 HydrophobicContact CB-CD1 3.97Å; L48-I203 HydrophobicContact CD1-CD1 4.02Å; L48-I203 HydrophobicContact CG-CD1 4.47Å; V51-I203 HydrophobicContact CG1-CB 4.48Å; V51-I203 HydrophobicContact CG1-CG2 4.16Å; L52-I203 HydrophobicContact CD1-CG2 4.31Å; Q199-I203 HydrophobicContact CG-CD1 4.47Å; Q199-I203 WeakPolarHBondContact O-CG1 3.09Å; Q199-I203 PolarHBondContact O-N 3.31Å; A200-I203 PolarHBondContact O-N 3.07Å; I203-A206 PolarHBondContact O-N 3.5Å; I203-I207 HydrophobicContact CG2-CD1 3.97Å; I203-I207 WeakPolarHBondContact O-CG1 3.23Å; I203-I207 PolarHBondContact O-N 2.87Å; I203-I207 VanDerWaalsContact O-N 3.08Å
204	V	83.9	Confident	82	Confident	22 Å²	22	28.2 Å²	28.2	13%	0.133	16%	0.156	C	C	.	.	H	α-helix	trans	-63	-44.2	175.7	172.4	0	0	0	0	111.3	V51 A55 A200 V201 G202 I208 L395	V51-V204 HydrophobicContact CG1-CG2 4.04Å; A55-V204 HydrophobicContact CB-CG2 4.08Å; A200-V204 WeakPolarHBondContact O-CG2 3.37Å; A200-V204 PolarHBondContact O-N 3Å; V201-V204 PolarHBondContact O-N 3.16Å; G202-V204 VanDerWaalsContact C-N 3.34Å; G202-V204 PolarHBondContact O-N 2.84Å; V204-I208 HydrophobicContact CG1-CD1 4.12Å; V204-I208 WeakPolarHBondContact O-CB 3.47Å; V204-I208 WeakPolarHBondContact O-CG1 3.47Å; V204-I208 PolarHBondContact O-N 3.35Å; V204-L395 HydrophobicContact CG1-CD2 4.19Å
205	G	81.9	Confident	83.1	Confident	0 Å²	0	24.3 Å²	24.3	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-65.5	-38.5	177	0	0	0	0	0	114	V201 G202	V201-G205 PolarHBondContact O-N 3.48Å; G202-G205 PolarHBondContact O-N 2.81Å
206	A	83.3	Confident	84.2	Confident	42 Å²	42	24.9 Å²	24.9	35%	0.347	14%	0.137	S	C	.	.	H	α-helix	trans	-67.6	-39.7	178.1	0	0	0	0	0	112.5	G202 I203 M209	G202-A206 WeakPolarHBondContact O-CB 3.47Å; G202-A206 PolarHBondContact O-N 2.89Å; I203-A206 PolarHBondContact O-N 3.5Å; A206-M209 WeakPolarHBondContact O-CG 3.33Å
207	I	87.6	Confident	85.3	Confident	26 Å²	26	23.5 Å²	23.5	13%	0.133	13%	0.13	C	C	.	.	H	α-helix	trans	-76.6	-46.6	176.7	-67.3	166.6	0	0	0	111.4	L52 A55 I203 M209	L52-I207 HydrophobicContact CD1-CD1 3.65Å; L52-I207 HydrophobicContact CG-CD1 4.17Å; A55-I207 HydrophobicContact CB-CB 4.33Å; A55-I207 HydrophobicContact CB-CD1 3.66Å; A55-I207 HydrophobicContact CB-CG2 4.45Å; I203-I207 HydrophobicContact CG2-CD1 3.97Å; I203-I207 WeakPolarHBondContact O-CG1 3.23Å; I203-I207 PolarHBondContact O-N 2.87Å; I203-I207 VanDerWaalsContact O-N 3.08Å; I207-M209 PolarHBondContact O-N 2.83Å
208	I	88.9	Confident	86.1	Confident	6 Å²	6	20.4 Å²	20.4	3%	0.031	12%	0.115	C	C	.	.	S	Bend	trans	-97.9	73.4	-173.1	-43.6	-178.1	0	0	0	109.1	A55 L58 V204 I213 L395	A55-I208 WeakPolarHBondContact O-CD1 3.31Å; L58-I208 HydrophobicContact CB-CD1 3.83Å; L58-I208 HydrophobicContact CD2-CD1 3.62Å; L58-I208 HydrophobicContact CG-CD1 3.56Å; V204-I208 HydrophobicContact CG1-CD1 4.12Å; V204-I208 WeakPolarHBondContact O-CB 3.47Å; V204-I208 WeakPolarHBondContact O-CG1 3.47Å; V204-I208 PolarHBondContact O-N 3.35Å; I208-I213 HydrophobicContact CG2-CD1 4.42Å; I208-L395 HydrophobicContact CB-CD1 4.15Å; I208-L395 HydrophobicContact CB-CD2 4.3Å; I208-L395 HydrophobicContact CG2-CD1 3.63Å; I208-L395 HydrophobicContact CG2-CD2 4.41Å; I208-L395 WeakPolarHBondContact O-CD1 3.28Å
209	M	90.6	Very high	86.9	Confident	37 Å²	37	20 Å²	20	18%	0.182	11%	0.112	C	C	.	.			trans	-69.7	125.2	-178.5	-55.4	176	104	0	0	110.9	S104 A206 I207 H211 N212	S104-M209 WeakPolarHBondContact OG-CE 3.2Å; A206-M209 WeakPolarHBondContact O-CG 3.33Å; I207-M209 PolarHBondContact O-N 2.83Å; M209-H211 VanDerWaalsContact C-N 3.33Å; M209-H211 PolarHBondContact O-N 3.47Å; M209-N212 HydrophobicContact CB-CB 4.23Å; M209-N212 PolarHBondContact O-N 3.47Å; M209-N212 PolarHBondContact SD-ND2 3.33Å
210	P	91.5	Very high	87.6	Confident	0 Å²	0	16.6 Å²	16.6	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-59.4	-41.3	-174.7	-22.4	30.9	0	0	0	113.1	I97 A100 N212 I213 Y214 Q391 L394 A398	I97-P210 HydrophobicContact CD1-CB 4.18Å; A100-P210 HydrophobicContact CB-CB 4.24Å; A100-P210 HydrophobicContact CB-CG 4.24Å; P210-N212 VanDerWaalsContact C-N 3.32Å; P210-N212 PolarHBondContact O-N 3.4Å; P210-I213 WeakPolarHBondContact O-CB 3.42Å; P210-I213 PolarHBondContact O-N 2.84Å; P210-Y214 WeakPolarHBondContact O-CD2 3.41Å; P210-Q391 VanDerWaalsContact CD-OE1 3.32Å; P210-Q391 WeakPolarHBondContact CG-O 3.35Å; P210-L394 HydrophobicContact CG-CB 4.25Å; P210-A398 HydrophobicContact CB-CB 3.74Å; P210-A398 WeakPolarHBondContact O-CB 3.14Å
211	H	91.6	Very high	88	Confident	0 Å²	0	19.1 Å²	19.1	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-68.6	-29	-178	64.3	-102.8	0	0	0	112.7	I101 S104 M209 I213 Y214 L215 A338	I101-H211 HydrophobicContact CD1-CB 4.4Å; I101-H211 HydrophobicContact CG1-CB 3.59Å; S104-H211 VanDerWaalsContact CB-CE1 3.49Å; S104-H211 WeakPolarHBondContact CB-CE1 3.48Å; S104-H211 PolarHBondContact OG-CE1 3.07Å; M209-H211 VanDerWaalsContact C-N 3.33Å; M209-H211 PolarHBondContact O-N 3.47Å; H211-I213 VanDerWaalsContact C-N 3.28Å; H211-I213 PolarHBondContact O-N 2.86Å; H211-Y214 PolarHBondContact O-N 3.14Å; H211-Y214 VanDerWaalsContact O-N 3.17Å; H211-L215 PolarHBondContact O-N 3.15Å; H211-A338 HydrophobicContact CB-CB 3.97Å
212	N	91.3	Very high	88.3	Confident	24 Å²	24	21.3 Å²	21.3	13%	0.128	12%	0.121	C	C	.	.	H	α-helix	trans	-67.6	-28.5	176.7	-78.1	-22	0	0	0	112.2	M209 P210 Y214 L215 H216	M209-N212 HydrophobicContact CB-CB 4.23Å; M209-N212 PolarHBondContact O-N 3.47Å; M209-N212 PolarHBondContact SD-ND2 3.33Å; P210-N212 VanDerWaalsContact C-N 3.32Å; P210-N212 PolarHBondContact O-N 3.4Å; N212-Y214 VanDerWaalsContact C-N 3.34Å; N212-L215 PolarHBondContact O-N 3.16Å; N212-H216 WeakPolarHBondContact O-CB 3.41Å; N212-H216 PolarHBondContact O-CD2 3.49Å; N212-H216 PolarHBondContact O-N 3.05Å
213	I	93.5	Very high	88.7	Confident	3 Å²	3	25.1 Å²	25.1	2%	0.015	13%	0.132	C	C	.	.	H	α-helix	trans	-63.2	-42.3	172.7	-59.3	-179.6	0	0	0	110.2	C62 A66 L77 I208 P210 H211 S217 L395 A398 V399 I402	C62-I213 HydrophobicContact CB-CD1 4.16Å; A66-I213 HydrophobicContact CB-CG2 3.93Å; A66-I213 VanDerWaalsContact CB-O 3.31Å; A66-I213 WeakPolarHBondContact CB-O 3.27Å; L77-I213 HydrophobicContact CD2-CG2 3.98Å; I208-I213 HydrophobicContact CG2-CD1 4.42Å; P210-I213 WeakPolarHBondContact O-CB 3.42Å; P210-I213 PolarHBondContact O-N 2.84Å; H211-I213 VanDerWaalsContact C-N 3.28Å; H211-I213 PolarHBondContact O-N 2.86Å; I213-S217 PolarHBondContact O-N 3.26Å; I213-L395 HydrophobicContact CD1-CD1 4.45Å; I213-A398 HydrophobicContact CB-CB 4.24Å; I213-A398 HydrophobicContact CD1-CB 3.94Å; I213-V399 HydrophobicContact CD1-CG2 3.73Å; I213-I402 HydrophobicContact CG2-CB 4.32Å; I213-I402 HydrophobicContact CG2-CG2 4.04Å
214	Y	93.4	Very high	88.8	Confident	3 Å²	3	33.7 Å²	33.7	1%	0.012	17%	0.171	C	C	.	.	H	α-helix	trans	-67.1	-47.1	173.7	-71.4	-88.8	0	0	0	111.5	L77 I97 P210 H211 N212 H216 S217 A218 V342 F346 F397 A398	L77-Y214 HydrophobicContact CB-CD1 3.76Å; L77-Y214 HydrophobicContact CB-CE1 3.88Å; L77-Y214 HydrophobicContact CD2-CD1 3.9Å; L77-Y214 HydrophobicContact CD2-CD2 4.41Å; L77-Y214 HydrophobicContact CD2-CE1 3.59Å; L77-Y214 HydrophobicContact CD2-CE2 4.14Å; L77-Y214 HydrophobicContact CD2-CG 4.29Å; L77-Y214 HydrophobicContact CG-CD1 3.88Å; L77-Y214 HydrophobicContact CG-CE1 3.48Å; L77-Y214 VanDerWaalsContact CG-CE1 3.48Å; I97-Y214 HydrophobicContact CD1-CD2 4.25Å; I97-Y214 HydrophobicContact CD1-CE2 3.53Å; I97-Y214 HydrophobicContact CG1-CD2 4.31Å; I97-Y214 HydrophobicContact CG1-CE2 3.62Å; I97-Y214 HydrophobicContact CG2-CD2 3.95Å; I97-Y214 HydrophobicContact CG2-CE2 4.12Å; P210-Y214 WeakPolarHBondContact O-CD2 3.41Å; H211-Y214 PolarHBondContact O-N 3.14Å; H211-Y214 VanDerWaalsContact O-N 3.17Å; N212-Y214 VanDerWaalsContact C-N 3.34Å; Y214-H216 PolarHBondContact O-N 2.91Å; Y214-S217 PolarHBondContact O-N 3.03Å; Y214-S217 VanDerWaalsContact O-N 3.16Å; Y214-S217 PolarHBondContact O-OG 2.94Å; Y214-A218 PolarHBondContact O-N 3.24Å; Y214-V342 HydrophobicContact CD1-CG2 4.28Å; Y214-V342 HydrophobicContact CG-CG2 3.98Å; Y214-F346 AromaticContact CD1-CE2 3.99Å; Y214-F346 HydrophobicContact CD1-CE2 3.99Å; Y214-F346 AromaticContact CE1-CE2 3.41Å; Y214-F346 HydrophobicContact CE1-CE2 3.41Å; Y214-F346 VanDerWaalsContact CE1-CE2 3.41Å; Y214-F346 AromaticContact CE1-CZ 3.64Å; Y214-F346 HydrophobicContact CE1-CZ 3.64Å; Y214-F346 AromaticContact CZ-CZ 3.95Å; Y214-F397 PolarHBondContact OH-O 3.2Å; Y214-A398 HydrophobicContact CD2-CB 4.28Å; Y214-A398 HydrophobicContact CE2-CB 3.69Å
215	L	91.6	Very high	88.9	Confident	5 Å²	5	33.7 Å²	33.7	3%	0.026	17%	0.171	C	C	.	.	H	α-helix	trans	-56.9	-50.2	179.5	-178.7	59.3	0	0	0	112.3	H211 N212 S217 A218 L219 T334 A338 F341	H211-L215 PolarHBondContact O-N 3.15Å; N212-L215 PolarHBondContact O-N 3.16Å; L215-S217 VanDerWaalsContact C-N 3.29Å; L215-S217 PolarHBondContact O-N 2.83Å; L215-A218 CarbonylContact O-C 3.45Å; L215-A218 WeakPolarHBondContact O-CA 3.34Å; L215-A218 PolarHBondContact O-N 3.11Å; L215-L219 HydrophobicContact CD1-CD1 4.07Å; L215-L219 HydrophobicContact CD1-CD2 4.21Å; L215-L219 HydrophobicContact CD1-CG 3.87Å; L215-L219 HydrophobicContact CD2-CD1 4.36Å; L215-L219 HydrophobicContact CG-CD1 3.79Å; L215-L219 HydrophobicContact CG-CG 4.06Å; L215-L219 WeakPolarHBondContact O-CG 3.31Å; L215-L219 PolarHBondContact O-N 2.83Å; L215-T334 HydrophobicContact CD2-CG2 4.06Å; L215-A338 HydrophobicContact CB-CB 4.16Å; L215-F341 HydrophobicContact CD1-CD2 3.94Å; L215-F341 HydrophobicContact CD1-CE2 4.04Å
216	H	91.1	Very high	89.2	Confident	57 Å²	57	36.5 Å²	36.5	26%	0.264	19%	0.187	S	C	.	.	H	α-helix	trans	-63.7	-32.4	178.3	-77.5	-69.3	0	0	0	113	N212 Y214 A218	N212-H216 WeakPolarHBondContact O-CB 3.41Å; N212-H216 PolarHBondContact O-CD2 3.49Å; N212-H216 PolarHBondContact O-N 3.05Å; Y214-H216 PolarHBondContact O-N 2.91Å; H216-A218 PolarHBondContact O-N 3.37Å
217	S	93.7	Very high	89.3	Confident	0 Å²	0	39.8 Å²	39.8	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-67.4	-21.2	173	78.3	0	0	0	0	113.6	A66 L77 I213 Y214 L215 V220	A66-S217 WeakPolarHBondContact O-CA 3.45Å; A66-S217 WeakPolarHBondContact O-CB 3.44Å; L77-S217 WeakPolarHBondContact CB-OG 3.49Å; L77-S217 PolarHBondContact N-OG 3.44Å; I213-S217 PolarHBondContact O-N 3.26Å; Y214-S217 PolarHBondContact O-N 3.03Å; Y214-S217 VanDerWaalsContact O-N 3.16Å; Y214-S217 PolarHBondContact O-OG 2.94Å; L215-S217 VanDerWaalsContact C-N 3.29Å; L215-S217 PolarHBondContact O-N 2.83Å; S217-V220 WeakPolarHBondContact O-CG2 3.47Å
218	A	90.8	Very high	89.2	Confident	2 Å²	2	44.2 Å²	44.2	2%	0.017	22%	0.219	C	C	.	.	H	α-helix	trans	-96.7	-39.1	178.3	0	0	0	0	0	113.1	D76 Y214 L215 H216 V220 K221 F341	D76-A218 HydrophobicContact CB-CB 3.81Å; Y214-A218 PolarHBondContact O-N 3.24Å; L215-A218 CarbonylContact O-C 3.45Å; L215-A218 WeakPolarHBondContact O-CA 3.34Å; L215-A218 PolarHBondContact O-N 3.11Å; H216-A218 PolarHBondContact O-N 3.37Å; A218-V220 PolarHBondContact O-N 3.3Å; A218-K221 WeakPolarHBondContact O-CB 3.07Å; A218-K221 PolarHBondContact O-N 2.93Å; A218-F341 HydrophobicContact CB-CB 3.8Å; A218-F341 HydrophobicContact CB-CD1 3.52Å; A218-F341 HydrophobicContact CB-CD2 3.46Å; A218-F341 VanDerWaalsContact CB-CD2 3.46Å; A218-F341 HydrophobicContact CB-CE1 3.88Å; A218-F341 HydrophobicContact CB-CE2 3.83Å; A218-F341 HydrophobicContact CB-CG 3.29Å; A218-F341 HydrophobicContact CB-CZ 4.03Å
219	L	88.3	Confident	89.2	Confident	54 Å²	54	50.7 Å²	50.7	28%	0.283	24%	0.243	S	C	.	.	H	α-helix	trans	-58.6	-32.3	179.8	-74.5	175.9	0	0	0	112.6	L215 K221 S222	L215-L219 HydrophobicContact CD1-CD1 4.07Å; L215-L219 HydrophobicContact CD1-CD2 4.21Å; L215-L219 HydrophobicContact CD1-CG 3.87Å; L215-L219 HydrophobicContact CD2-CD1 4.36Å; L215-L219 HydrophobicContact CG-CD1 3.79Å; L215-L219 HydrophobicContact CG-CG 4.06Å; L215-L219 WeakPolarHBondContact O-CG 3.31Å; L215-L219 PolarHBondContact O-N 2.83Å; L219-K221 PolarHBondContact O-N 3.37Å; L219-K221 VanDerWaalsContact O-N 3.17Å; L219-S222 VanDerWaalsContact O-CB 3.26Å; L219-S222 WeakPolarHBondContact O-CB 3.45Å; L219-S222 PolarHBondContact O-N 3.2Å; L219-S222 PolarHBondContact O-OG 2.81Å
220	V	89.6	Confident	89	Confident	7 Å²	7	56.3 Å²	56.3	4%	0.042	26%	0.262	C	S	.	.	G	3₁₀ helix	trans	-61.7	-20.9	173.8	-62.3	0	0	0	0	113.8	A67 V71 S217 A218 S222 F240	A67-V220 HydrophobicContact CB-CG1 3.81Å; V71-V220 HydrophobicContact CG2-CB 3.88Å; V71-V220 HydrophobicContact CG2-CG1 4.08Å; V71-V220 HydrophobicContact CG2-CG2 4.19Å; S217-V220 WeakPolarHBondContact O-CG2 3.47Å; A218-V220 PolarHBondContact O-N 3.3Å; V220-S222 PolarHBondContact O-N 2.95Å; V220-F240 HydrophobicContact CB-CD2 4.32Å; V220-F240 HydrophobicContact CB-CE1 4.16Å; V220-F240 HydrophobicContact CB-CE2 3.81Å; V220-F240 HydrophobicContact CB-CZ 3.7Å; V220-F240 HydrophobicContact CG1-CD1 3.78Å; V220-F240 HydrophobicContact CG1-CD2 3.85Å; V220-F240 HydrophobicContact CG1-CE1 3.74Å; V220-F240 HydrophobicContact CG1-CE2 3.81Å; V220-F240 HydrophobicContact CG1-CG 3.83Å; V220-F240 HydrophobicContact CG1-CZ 3.74Å
221	K	86.9	Confident	88.9	Confident	68 Å²	68	61.3 Å²	61.3	30%	0.296	29%	0.292	S	S	.	.	G	3₁₀ helix	trans	-71.6	-12.7	174.5	-60.4	162.7	65.9	171	0	112.5	D76 E79 A218 L219	D76-K221 HydrophobicContact CB-CD 4.16Å; D76-K221 IonicContact OD2-NZ 3.8Å; D76-K221 PolarHBondContact OD2-NZ 2.84Å; E79-K221 IonicContact OE1-NZ 2.75Å; E79-K221 PolarHBondContact OE1-NZ 3.44Å; E79-K221 IonicContact OE2-NZ 3.22Å; E79-K221 PolarHBondContact OE2-NZ 2.96Å; A218-K221 WeakPolarHBondContact O-CB 3.07Å; A218-K221 PolarHBondContact O-N 2.93Å; L219-K221 PolarHBondContact O-N 3.37Å; L219-K221 VanDerWaalsContact O-N 3.17Å
222	S	84.7	Confident	88.9	Confident	57 Å²	57	63 Å²	63	40%	0.399	30%	0.301	S	S	.	.	G	3₁₀ helix	trans	-76.5	-21.3	177.8	69.7	0	0	0	0	114.4	L219 V220	L219-S222 VanDerWaalsContact O-CB 3.26Å; L219-S222 WeakPolarHBondContact O-CB 3.45Å; L219-S222 PolarHBondContact O-N 3.2Å; L219-S222 PolarHBondContact O-OG 2.81Å; V220-S222 PolarHBondContact O-N 2.95Å
223	R	86.4	Confident	88.8	Confident	90 Å²	90	62 Å²	62	34%	0.34	30%	0.296	S	S	.	.	S	Bend	trans	-94.4	129.5	172.8	-53.2	-69.2	-173.1	-140.4	-5.7	107.7	E152 V225 F240	E152-R223 IonicContact OE1-CZ 2.75Å; E152-R223 IonicContact OE1-NH1 3.52Å; E152-R223 IonicContact OE1-NH2 3.13Å; E152-R223 IonicContact OE2-CZ 3.66Å; E152-R223 IonicContact OE2-NH1 2.69Å; E152-R223 PolarHBondContact OE2-NH1 3.25Å; E152-R223 IonicContact OE2-NH2 3.34Å; E152-R223 PolarHBondContact OE2-NH2 3.04Å; R223-V225 PolarHBondContact O-N 2.96Å; R223-F240 HydrophobicContact CB-CZ 3.97Å; R223-F240 HydrophobicContact CG-CE1 3.99Å; R223-F240 HydrophobicContact CG-CZ 3.6Å
224	E	83.7	Confident	88.6	Confident	204 Å²	204	71 Å²	71	95%	0.953	33%	0.33	S	S	*	.			trans	-71.7	120.5	173.9	-68.3	-178.2	178	0	0	109.6
225	V	87.1	Confident	88.6	Confident	22 Å²	22	75.3 Å²	75.3	13%	0.133	35%	0.35	C	S	.	.			trans	-127.2	124	177.5	-178.5	0	0	0	0	108	R223 R227 D232 V233 A236	R223-V225 PolarHBondContact O-N 2.96Å; V225-R227 PolarHBondContact O-N 3.21Å; V225-R227 VanDerWaalsContact O-N 3.15Å; V225-D232 HydrophobicContact CG1-CB 4.49Å; V225-V233 HydrophobicContact CG1-CG2 4.33Å; V225-A236 HydrophobicContact CG1-CB 4Å; V225-A236 HydrophobicContact CG2-CB 3.79Å
226	D	87.1	Confident	88.6	Confident	60 Å²	60	75.7 Å²	75.7	32%	0.321	35%	0.354	S	S	.	.			trans	-73	104.6	173	-177.2	-5.2	0	0	0	109.7	T228 R229	D226-T228 VanDerWaalsContact CG-OG1 3.3Å; D226-T228 PolarHBondContact O-N 2.76Å; D226-T228 VanDerWaalsContact OD1-CB 3.3Å; D226-T228 WeakPolarHBondContact OD1-CB 3.39Å; D226-T228 WeakPolarHBondContact OD1-CG2 3.4Å; D226-T228 PolarHBondContact OD1-N 3.11Å; D226-T228 PolarHBondContact OD1-OG1 3.28Å; D226-T228 PolarHBondContact OD2-OG1 3.07Å; D226-R229 PolarHBondContact O-N 3.13Å; D226-R229 IonicContact OD2-CZ 3.16Å; D226-R229 IonicContact OD2-NE 2.96Å
227	R	85.5	Confident	88.6	Confident	110 Å²	110	74.5 Å²	74.5	42%	0.415	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.8	-8.5	-178.2	-60.4	178.3	-170.6	85	0.7	113.1	V71 V225	V71-R227 PolarHBondContact O-NE 3.16Å; V225-R227 PolarHBondContact O-N 3.21Å; V225-R227 VanDerWaalsContact O-N 3.15Å
228	T	85.8	Confident	88.6	Confident	120 Å²	120	79.8 Å²	79.8	74%	0.736	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.8	-30.8	172.5	74.8	0	0	0	0	111.1	D226	D226-T228 VanDerWaalsContact CG-OG1 3.3Å; D226-T228 PolarHBondContact O-N 2.76Å; D226-T228 VanDerWaalsContact OD1-CB 3.3Å; D226-T228 WeakPolarHBondContact OD1-CB 3.39Å; D226-T228 WeakPolarHBondContact OD1-CG2 3.4Å; D226-T228 PolarHBondContact OD1-N 3.11Å; D226-T228 PolarHBondContact OD1-OG1 3.28Å; D226-T228 PolarHBondContact OD2-OG1 3.07Å
229	R	88.8	Confident	88.7	Confident	141 Å²	141	86.2 Å²	86.2	53%	0.532	40%	0.4	S	S	.	.			trans	-95.1	115.6	-179.7	-62.6	-164.3	-55.7	-143.7	-1.9	111.6	D226 V231 D232 V233	D226-R229 PolarHBondContact O-N 3.13Å; D226-R229 IonicContact OD2-CZ 3.16Å; D226-R229 IonicContact OD2-NE 2.96Å; R229-V231 PolarHBondContact O-N 3.5Å; R229-D232 HydrophobicContact CB-CB 4.27Å; R229-D232 WeakPolarHBondContact CB-OD1 3.26Å; R229-D232 IonicContact CZ-OD1 3.68Å; R229-D232 IonicContact CZ-OD2 2.68Å; R229-D232 IonicContact NE-OD1 2.94Å; R229-D232 PolarHBondContact NE-OD1 2.96Å; R229-D232 VanDerWaalsContact NE-OD1 3.16Å; R229-D232 IonicContact NE-OD2 3.78Å; R229-D232 PolarHBondContact NE-OD2 3.48Å; R229-D232 IonicContact NH2-OD1 2.94Å; R229-D232 IonicContact NH2-OD2 2.89Å; R229-D232 PolarHBondContact NH2-OD2 3.34Å; R229-D232 PolarHBondContact O-N 3.02Å; R229-V233 PolarHBondContact O-N 3.36Å
230	R	87	Confident	88.9	Confident	156 Å²	156	84.7 Å²	84.7	59%	0.589	39%	0.391	S	S	*	.	H	α-helix	trans	-63.9	-27.9	-177.5	-59.3	175.7	-179.8	-148.5	-12.6	113.7	R234 E414	R230-R234 PolarHBondContact O-N 3.2Å; R230-E414 IonicContact CZ-OE1 3.53Å; R230-E414 IonicContact CZ-OE2 2.77Å; R230-E414 VanDerWaalsContact CZ-OE2 3.32Å; R230-E414 IonicContact NH1-OE1 2.67Å; R230-E414 PolarHBondContact NH1-OE1 2.84Å; R230-E414 IonicContact NH1-OE2 3.5Å; R230-E414 PolarHBondContact NH1-OE2 3.16Å; R230-E414 IonicContact NH2-OE1 3.83Å; R230-E414 PolarHBondContact NH2-OE1 2.96Å; R230-E414 IonicContact NH2-OE2 3.44Å
231	V	90.1	Very high	89	Confident	105 Å²	105	87 Å²	87	64%	0.636	40%	0.403	S	S	*	.	H	α-helix	trans	-68.5	-52.8	179.7	-177.9	0	0	0	0	109.4	R229 V233 R234 E235	R229-V231 PolarHBondContact O-N 3.5Å; V231-V233 VanDerWaalsContact C-N 3.32Å; V231-V233 PolarHBondContact O-N 2.86Å; V231-R234 CarbonylContact O-C 3.59Å; V231-R234 WeakPolarHBondContact O-CA 3.29Å; V231-R234 WeakPolarHBondContact O-CB 3.4Å; V231-R234 PolarHBondContact O-N 3.29Å; V231-E235 WeakPolarHBondContact O-CB 3.25Å; V231-E235 PolarHBondContact O-N 3.03Å
232	D	89.9	Confident	89.3	Confident	35 Å²	35	87.3 Å²	87.3	19%	0.187	41%	0.407	C	S	.	.	H	α-helix	trans	-54.9	-44.4	177.7	-51.6	38.3	0	0	0	111.9	V225 R229 R234 E235 A236	V225-D232 HydrophobicContact CG1-CB 4.49Å; R229-D232 HydrophobicContact CB-CB 4.27Å; R229-D232 WeakPolarHBondContact CB-OD1 3.26Å; R229-D232 IonicContact CZ-OD1 3.68Å; R229-D232 IonicContact CZ-OD2 2.68Å; R229-D232 IonicContact NE-OD1 2.94Å; R229-D232 PolarHBondContact NE-OD1 2.96Å; R229-D232 VanDerWaalsContact NE-OD1 3.16Å; R229-D232 IonicContact NE-OD2 3.78Å; R229-D232 PolarHBondContact NE-OD2 3.48Å; R229-D232 IonicContact NH2-OD1 2.94Å; R229-D232 IonicContact NH2-OD2 2.89Å; R229-D232 PolarHBondContact NH2-OD2 3.34Å; R229-D232 PolarHBondContact O-N 3.02Å; D232-R234 VanDerWaalsContact C-N 3.33Å; D232-R234 PolarHBondContact O-N 3.44Å; D232-E235 PolarHBondContact O-N 3.3Å; D232-A236 VanDerWaalsContact O-CB 3.27Å; D232-A236 WeakPolarHBondContact O-CB 3.35Å; D232-A236 PolarHBondContact O-N 3.19Å
233	V	90.3	Very high	89.6	Confident	4 Å²	4	89.2 Å²	89.2	2%	0.024	41%	0.41	C	S	.	.	H	α-helix	trans	-62.7	-38.9	175.5	173.8	0	0	0	0	111.7	V71 V72 V225 R229 V231 N237 F415	V71-V233 HydrophobicContact CG1-CG1 4.24Å; V72-V233 HydrophobicContact CG2-CG1 4.06Å; V225-V233 HydrophobicContact CG1-CG2 4.33Å; R229-V233 PolarHBondContact O-N 3.36Å; V231-V233 VanDerWaalsContact C-N 3.32Å; V231-V233 PolarHBondContact O-N 2.86Å; V233-N237 WeakPolarHBondContact O-CB 3.31Å; V233-N237 PolarHBondContact O-N 3.13Å; V233-N237 VanDerWaalsContact O-N 3.16Å; V233-N237 PolarHBondContact O-ND2 3.22Å; V233-F415 HydrophobicContact CB-CE2 4.24Å; V233-F415 HydrophobicContact CB-CZ 4Å; V233-F415 HydrophobicContact CG1-CD2 4.16Å; V233-F415 HydrophobicContact CG1-CE1 4.11Å; V233-F415 HydrophobicContact CG1-CE2 3.6Å; V233-F415 HydrophobicContact CG1-CZ 3.57Å
234	R	89.7	Confident	89.9	Confident	192 Å²	192	85.5 Å²	85.5	73%	0.725	40%	0.398	S	S	*	.	H	α-helix	trans	-72	-38.7	177.9	-176.3	176.3	179.3	168.5	-0.9	112	R230 V231 D232 N237 M238 F415	R230-R234 PolarHBondContact O-N 3.2Å; V231-R234 CarbonylContact O-C 3.59Å; V231-R234 WeakPolarHBondContact O-CA 3.29Å; V231-R234 WeakPolarHBondContact O-CB 3.4Å; V231-R234 PolarHBondContact O-N 3.29Å; D232-R234 VanDerWaalsContact C-N 3.33Å; D232-R234 PolarHBondContact O-N 3.44Å; R234-N237 PolarHBondContact O-N 3.36Å; R234-M238 PolarHBondContact O-N 3.14Å; R234-M238 VanDerWaalsContact O-N 3.12Å; R234-F415 HydrophobicContact CB-CE1 4.49Å
235	E	92.8	Very high	90.4	Very high	93 Å²	93	78.1 Å²	78.1	44%	0.435	37%	0.367	S	S	.	.	H	α-helix	trans	-66.8	-48.5	177.2	179.3	170.1	-165.7	0	0	111.4	V231 D232 N237 M238 Y239	V231-E235 WeakPolarHBondContact O-CB 3.25Å; V231-E235 PolarHBondContact O-N 3.03Å; D232-E235 PolarHBondContact O-N 3.3Å; E235-N237 VanDerWaalsContact C-N 3.31Å; E235-N237 PolarHBondContact O-N 3.14Å; E235-M238 WeakPolarHBondContact O-CA 3.49Å; E235-M238 WeakPolarHBondContact O-CB 3.23Å; E235-M238 PolarHBondContact O-N 2.85Å; E235-Y239 HydrophobicContact CG-CD2 3.81Å; E235-Y239 HydrophobicContact CG-CE2 3.44Å; E235-Y239 VanDerWaalsContact CG-CE2 3.44Å; E235-Y239 WeakPolarHBondContact O-CD2 3.44Å; E235-Y239 PolarHBondContact O-N 3.2Å
236	A	92.1	Very high	90.6	Very high	12 Å²	12	82.1 Å²	82.1	10%	0.099	39%	0.387	C	S	.	.	H	α-helix	trans	-56.5	-44.5	172.8	0	0	0	0	0	111.9	V71 V225 D232 M238 Y239 F240	V71-A236 HydrophobicContact CG1-CB 4.01Å; V225-A236 HydrophobicContact CG1-CB 4Å; V225-A236 HydrophobicContact CG2-CB 3.79Å; D232-A236 VanDerWaalsContact O-CB 3.27Å; D232-A236 WeakPolarHBondContact O-CB 3.35Å; D232-A236 PolarHBondContact O-N 3.19Å; A236-M238 VanDerWaalsContact C-N 3.25Å; A236-M238 PolarHBondContact O-N 2.97Å; A236-Y239 PolarHBondContact O-N 3.41Å; A236-F240 HydrophobicContact CB-CD2 4.42Å; A236-F240 HydrophobicContact CB-CE2 4.35Å; A236-F240 WeakPolarHBondContact O-CD2 3.44Å; A236-F240 PolarHBondContact O-N 3.38Å
237	N	91.3	Very high	90.8	Very high	32 Å²	32	82 Å²	82	17%	0.171	39%	0.394	C	S	.	.	H	α-helix	trans	-61.9	-28.9	174.9	-85.7	-61.8	0	0	0	113.7	R68 V233 R234 E235 L241	R68-N237 VanDerWaalsContact CA-OD1 3.29Å; R68-N237 WeakPolarHBondContact CA-OD1 3.46Å; R68-N237 WeakPolarHBondContact CB-OD1 3.47Å; R68-N237 WeakPolarHBondContact CG-OD1 3.43Å; V233-N237 WeakPolarHBondContact O-CB 3.31Å; V233-N237 PolarHBondContact O-N 3.13Å; V233-N237 VanDerWaalsContact O-N 3.16Å; V233-N237 PolarHBondContact O-ND2 3.22Å; R234-N237 PolarHBondContact O-N 3.36Å; E235-N237 VanDerWaalsContact C-N 3.31Å; E235-N237 PolarHBondContact O-N 3.14Å; N237-L241 WeakPolarHBondContact O-CB 3.34Å; N237-L241 PolarHBondContact O-N 3.3Å
238	M	92.4	Very high	91	Very high	111 Å²	111	77.5 Å²	77.5	55%	0.547	38%	0.378	S	S	.	.	H	α-helix	trans	-74.3	-46.5	173	173.6	179.3	152.6	0	0	111	R234 E235 A236 L241 I242	R234-M238 PolarHBondContact O-N 3.14Å; R234-M238 VanDerWaalsContact O-N 3.12Å; E235-M238 WeakPolarHBondContact O-CA 3.49Å; E235-M238 WeakPolarHBondContact O-CB 3.23Å; E235-M238 PolarHBondContact O-N 2.85Å; A236-M238 VanDerWaalsContact C-N 3.25Å; A236-M238 PolarHBondContact O-N 2.97Å; M238-L241 WeakPolarHBondContact O-CB 3.44Å; M238-L241 PolarHBondContact O-N 3.04Å; M238-I242 HydrophobicContact CE-CD1 3.74Å; M238-I242 HydrophobicContact CG-CD1 3.94Å; M238-I242 WeakPolarHBondContact O-CG1 3.21Å; M238-I242 PolarHBondContact O-N 3.33Å
239	Y	93.3	Very high	91.4	Very high	137 Å²	137	74.5 Å²	74.5	54%	0.537	36%	0.362	S	S	.	.	H	α-helix	trans	-62.8	-46.6	179.3	-74.8	-57.9	0	0	0	112.6	E235 A236 L241 I242 E243	E235-Y239 HydrophobicContact CG-CD2 3.81Å; E235-Y239 HydrophobicContact CG-CE2 3.44Å; E235-Y239 VanDerWaalsContact CG-CE2 3.44Å; E235-Y239 WeakPolarHBondContact O-CD2 3.44Å; E235-Y239 PolarHBondContact O-N 3.2Å; A236-Y239 PolarHBondContact O-N 3.41Å; Y239-L241 VanDerWaalsContact C-N 3.26Å; Y239-L241 PolarHBondContact O-N 3.33Å; Y239-I242 PolarHBondContact O-N 3.28Å; Y239-I242 VanDerWaalsContact O-N 3.11Å; Y239-E243 WeakPolarHBondContact O-CB 3.19Å; Y239-E243 PolarHBondContact O-N 3.19Å
240	F	91.8	Very high	91.6	Very high	23 Å²	23	70.2 Å²	70.2	10%	0.101	35%	0.351	C	S	.	.	H	α-helix	trans	-64	-29.8	175.8	-72.6	-58.6	0	0	0	113.2	A67 V71 V220 R223 A236 A244	A67-F240 HydrophobicContact CB-CB 4.41Å; V71-F240 HydrophobicContact CG2-CD2 3.47Å; V71-F240 VanDerWaalsContact CG2-CD2 3.47Å; V71-F240 HydrophobicContact CG2-CE2 3.57Å; V220-F240 HydrophobicContact CB-CD2 4.32Å; V220-F240 HydrophobicContact CB-CE1 4.16Å; V220-F240 HydrophobicContact CB-CE2 3.81Å; V220-F240 HydrophobicContact CB-CZ 3.7Å; V220-F240 HydrophobicContact CG1-CD1 3.78Å; V220-F240 HydrophobicContact CG1-CD2 3.85Å; V220-F240 HydrophobicContact CG1-CE1 3.74Å; V220-F240 HydrophobicContact CG1-CE2 3.81Å; V220-F240 HydrophobicContact CG1-CG 3.83Å; V220-F240 HydrophobicContact CG1-CZ 3.74Å; R223-F240 HydrophobicContact CB-CZ 3.97Å; R223-F240 HydrophobicContact CG-CE1 3.99Å; R223-F240 HydrophobicContact CG-CZ 3.6Å; A236-F240 HydrophobicContact CB-CD2 4.42Å; A236-F240 HydrophobicContact CB-CE2 4.35Å; A236-F240 WeakPolarHBondContact O-CD2 3.44Å; A236-F240 PolarHBondContact O-N 3.38Å; F240-A244 VanDerWaalsContact O-CB 3.29Å; F240-A244 WeakPolarHBondContact O-CB 3.34Å; F240-A244 PolarHBondContact O-N 2.7Å
241	L	92.5	Very high	91.8	Very high	55 Å²	55	65 Å²	65	29%	0.288	34%	0.339	S	S	.	.	H	α-helix	trans	-67.9	-43	171.9	176.5	58.7	0	0	0	111.5	R64 N237 M238 Y239 T245	R64-L241 HydrophobicContact CB-CD1 4.31Å; R64-L241 HydrophobicContact CG-CD1 3.95Å; N237-L241 WeakPolarHBondContact O-CB 3.34Å; N237-L241 PolarHBondContact O-N 3.3Å; M238-L241 WeakPolarHBondContact O-CB 3.44Å; M238-L241 PolarHBondContact O-N 3.04Å; Y239-L241 VanDerWaalsContact C-N 3.26Å; Y239-L241 PolarHBondContact O-N 3.33Å; L241-T245 VanDerWaalsContact O-CB 3.26Å; L241-T245 WeakPolarHBondContact O-CB 3.3Å; L241-T245 PolarHBondContact O-N 2.75Å; L241-T245 PolarHBondContact O-OG1 3.15Å
242	I	93.6	Very high	92	Very high	74 Å²	74	61.5 Å²	61.5	38%	0.379	32%	0.315	S	S	.	.	H	α-helix	trans	-63.8	-47.3	177.3	-68.3	165.2	0	0	0	110.1	M238 Y239 T245 I246	M238-I242 HydrophobicContact CE-CD1 3.74Å; M238-I242 HydrophobicContact CG-CD1 3.94Å; M238-I242 WeakPolarHBondContact O-CG1 3.21Å; M238-I242 PolarHBondContact O-N 3.33Å; Y239-I242 PolarHBondContact O-N 3.28Å; Y239-I242 VanDerWaalsContact O-N 3.11Å; I242-T245 PolarHBondContact O-N 3.32Å; I242-I246 HydrophobicContact CG2-CD1 3.73Å; I242-I246 HydrophobicContact CG2-CG1 4.45Å; I242-I246 WeakPolarHBondContact O-CG1 3.46Å; I242-I246 PolarHBondContact O-N 3.42Å
243	E	91.2	Very high	92.1	Very high	98 Å²	98	63.5 Å²	63.5	46%	0.458	33%	0.325	S	S	.	.	H	α-helix	trans	-56.5	-52.8	177.4	-173.2	177.5	169.9	0	0	111.7	Y239 T245 I246 A247	Y239-E243 WeakPolarHBondContact O-CB 3.19Å; Y239-E243 PolarHBondContact O-N 3.19Å; E243-T245 VanDerWaalsContact C-N 3.33Å; E243-T245 PolarHBondContact O-N 3.3Å; E243-I246 PolarHBondContact O-N 3.28Å; E243-A247 WeakPolarHBondContact O-CB 3.49Å; E243-A247 PolarHBondContact O-N 3.09Å
244	A	91.3	Very high	92.2	Very high	12 Å²	12	63.9 Å²	63.9	10%	0.099	33%	0.327	C	S	.	.	H	α-helix	trans	-62.9	-37.1	177	0	0	0	0	0	112.8	L60 F240 L248	L60-A244 HydrophobicContact CD1-CB 4.12Å; F240-A244 VanDerWaalsContact O-CB 3.29Å; F240-A244 WeakPolarHBondContact O-CB 3.34Å; F240-A244 PolarHBondContact O-N 2.7Å; A244-L248 WeakPolarHBondContact O-CB 3.46Å; A244-L248 PolarHBondContact O-N 3.28Å
245	T	94.1	Very high	92.3	Very high	49 Å²	49	57.1 Å²	57.1	30%	0.301	31%	0.305	S	S	.	.	H	α-helix	trans	-66.2	-43.6	177.9	-57.2	0	0	0	0	111.3	L60 L241 I242 E243 S249	L60-T245 HydrophobicContact CD2-CG2 4.36Å; L241-T245 VanDerWaalsContact O-CB 3.26Å; L241-T245 WeakPolarHBondContact O-CB 3.3Å; L241-T245 PolarHBondContact O-N 2.75Å; L241-T245 PolarHBondContact O-OG1 3.15Å; I242-T245 PolarHBondContact O-N 3.32Å; E243-T245 VanDerWaalsContact C-N 3.33Å; E243-T245 PolarHBondContact O-N 3.3Å; T245-S249 VanDerWaalsContact O-CB 3.27Å; T245-S249 WeakPolarHBondContact O-CB 3.35Å; T245-S249 PolarHBondContact O-N 3.19Å; T245-S249 PolarHBondContact O-OG 3.41Å
246	I	93.1	Very high	92.1	Very high	105 Å²	105	54.1 Å²	54.1	54%	0.538	29%	0.292	S	S	.	.	H	α-helix	trans	-65.2	-49.3	177.4	-67.5	167.8	0	0	0	110.1	I242 E243 L248 S249 V250	I242-I246 HydrophobicContact CG2-CD1 3.73Å; I242-I246 HydrophobicContact CG2-CG1 4.45Å; I242-I246 WeakPolarHBondContact O-CG1 3.46Å; I242-I246 PolarHBondContact O-N 3.42Å; E243-I246 PolarHBondContact O-N 3.28Å; I246-L248 PolarHBondContact O-N 2.92Å; I246-S249 PolarHBondContact O-N 2.92Å; I246-V250 WeakPolarHBondContact O-CG2 3.33Å; I246-V250 PolarHBondContact O-N 3.03Å
247	A	90	Very high	92.1	Very high	57 Å²	57	55.5 Å²	55.5	47%	0.471	30%	0.296	S	S	.	.	H	α-helix	trans	-59.6	-47.5	-179.6	0	0	0	0	0	112.3	E243 S249 V250 S251	E243-A247 WeakPolarHBondContact O-CB 3.49Å; E243-A247 PolarHBondContact O-N 3.09Å; A247-S249 VanDerWaalsContact C-N 3.35Å; A247-S249 PolarHBondContact O-N 3.34Å; A247-V250 PolarHBondContact O-N 2.66Å; A247-S251 PolarHBondContact O-N 3.25Å
248	L	91.2	Very high	91.9	Very high	17 Å²	17	55.4 Å²	55.4	9%	0.089	30%	0.296	C	S	.	.	H	α-helix	trans	-69.7	-28.7	176.7	-76.3	179.9	0	0	0	113.3	T56 L60 Q63 A244 I246 S251 F252	T56-L248 HydrophobicContact CG2-CB 4.35Å; L60-L248 HydrophobicContact CB-CD1 3.56Å; L60-L248 HydrophobicContact CD1-CD1 3.93Å; L60-L248 HydrophobicContact CG-CD1 4.33Å; Q63-L248 VanDerWaalsContact OE1-CD1 3.29Å; A244-L248 WeakPolarHBondContact O-CB 3.46Å; A244-L248 PolarHBondContact O-N 3.28Å; I246-L248 PolarHBondContact O-N 2.92Å; L248-S251 PolarHBondContact O-N 3.45Å; L248-F252 VanDerWaalsContact O-CB 3.24Å; L248-F252 WeakPolarHBondContact O-CB 3.32Å; L248-F252 PolarHBondContact O-N 3.47Å
249	S	93.4	Very high	91.6	Very high	56 Å²	56	52.3 Å²	52.3	39%	0.392	28%	0.281	S	S	.	.	H	α-helix	trans	-66.3	-41.5	173.2	-61.1	0	0	0	0	111.4	T245 I246 A247 F252 I253	T245-S249 VanDerWaalsContact O-CB 3.27Å; T245-S249 WeakPolarHBondContact O-CB 3.35Å; T245-S249 PolarHBondContact O-N 3.19Å; T245-S249 PolarHBondContact O-OG 3.41Å; I246-S249 PolarHBondContact O-N 2.92Å; A247-S249 VanDerWaalsContact C-N 3.35Å; A247-S249 PolarHBondContact O-N 3.34Å; S249-F252 PolarHBondContact O-N 3.35Å; S249-I253 VanDerWaalsContact O-CG1 3.28Å; S249-I253 WeakPolarHBondContact O-CG1 3.44Å; S249-I253 PolarHBondContact O-N 3.01Å
250	V	93.2	Very high	91.3	Very high	51 Å²	51	45.9 Å²	45.9	31%	0.309	26%	0.256	S	S	.	.	H	α-helix	trans	-65.5	-45.3	174.3	174.6	0	0	0	0	110.9	I159 I246 A247 F252 I253 I254	I159-V250 HydrophobicContact CG2-CG1 3.72Å; I246-V250 WeakPolarHBondContact O-CG2 3.33Å; I246-V250 PolarHBondContact O-N 3.03Å; A247-V250 PolarHBondContact O-N 2.66Å; V250-F252 VanDerWaalsContact C-N 3.34Å; V250-F252 PolarHBondContact O-N 3.24Å; V250-I253 PolarHBondContact O-N 2.96Å; V250-I254 HydrophobicContact CG1-CD1 4.02Å; V250-I254 WeakPolarHBondContact O-CG1 3.44Å; V250-I254 PolarHBondContact O-N 2.96Å
251	S	91.4	Very high	91.1	Very high	47 Å²	47	44.9 Å²	44.9	33%	0.329	25%	0.252	S	S	.	.	H	α-helix	trans	-59.4	-42.6	175.5	178.2	0	0	0	0	112.3	A247 L248 I254 N255	A247-S251 PolarHBondContact O-N 3.25Å; L248-S251 PolarHBondContact O-N 3.45Å; S251-I254 PolarHBondContact O-N 3.49Å; S251-N255 WeakPolarHBondContact O-CB 3.5Å; S251-N255 VanDerWaalsContact O-CG 3.26Å; S251-N255 PolarHBondContact O-N 3.01Å; S251-N255 PolarHBondContact O-ND2 3.37Å
252	F	92.6	Very high	90.7	Very high	31 Å²	31	43.5 Å²	43.5	14%	0.136	24%	0.244	C	C	.	.	H	α-helix	trans	-62.6	-41.8	175.1	167.3	-99.7	0	0	0	112.8	L52 L53 T56 L184 L248 S249 V250 N255 L256	L52-F252 HydrophobicContact CD2-CD2 4.24Å; L52-F252 HydrophobicContact CD2-CE2 4.13Å; L52-F252 HydrophobicContact CG-CD2 4.5Å; L53-F252 HydrophobicContact CB-CE2 4.04Å; L53-F252 HydrophobicContact CD1-CD2 4.45Å; L53-F252 HydrophobicContact CD1-CE1 4.41Å; L53-F252 HydrophobicContact CD1-CE2 3.73Å; L53-F252 HydrophobicContact CD1-CZ 3.71Å; T56-F252 HydrophobicContact CG2-CB 3.85Å; T56-F252 HydrophobicContact CG2-CD2 4.45Å; T56-F252 HydrophobicContact CG2-CG 4.45Å; L184-F252 HydrophobicContact CD1-CE2 4.11Å; L184-F252 HydrophobicContact CD1-CZ 3.71Å; L184-F252 HydrophobicContact CD2-CZ 4.23Å; L248-F252 VanDerWaalsContact O-CB 3.24Å; L248-F252 WeakPolarHBondContact O-CB 3.32Å; L248-F252 PolarHBondContact O-N 3.47Å; S249-F252 PolarHBondContact O-N 3.35Å; V250-F252 VanDerWaalsContact C-N 3.34Å; V250-F252 PolarHBondContact O-N 3.24Å; F252-N255 PolarHBondContact O-N 3.23Å; F252-L256 HydrophobicContact CE1-CD2 4.34Å; F252-L256 HydrophobicContact CZ-CD2 4.41Å; F252-L256 WeakPolarHBondContact O-CB 3.19Å; F252-L256 PolarHBondContact O-N 3.48Å
253	I	93.1	Very high	90	Very high	77 Å²	77	40.6 Å²	40.6	40%	0.395	23%	0.232	S	C	.	.	H	α-helix	trans	-63	-43.2	175.6	-70	164.4	0	0	0	110.7	S249 V250 L256 F257	S249-I253 VanDerWaalsContact O-CG1 3.28Å; S249-I253 WeakPolarHBondContact O-CG1 3.44Å; S249-I253 PolarHBondContact O-N 3.01Å; V250-I253 PolarHBondContact O-N 2.96Å; I253-L256 PolarHBondContact O-N 3.29Å; I253-F257 HydrophobicContact CG2-CD1 4.46Å; I253-F257 HydrophobicContact CG2-CD2 4.11Å; I253-F257 HydrophobicContact CG2-CE1 3.94Å; I253-F257 HydrophobicContact CG2-CE2 3.54Å; I253-F257 HydrophobicContact CG2-CZ 3.45Å; I253-F257 VanDerWaalsContact CG2-CZ 3.45Å; I253-F257 VanDerWaalsContact O-CG 3.24Å; I253-F257 WeakPolarHBondContact O-CG 3.38Å; I253-F257 PolarHBondContact O-N 2.88Å
254	I	92.4	Very high	89.6	Confident	13 Å²	13	40.5 Å²	40.5	7%	0.067	23%	0.232	C	C	.	.	H	α-helix	trans	-59.5	-49.4	174.9	-72.1	165.1	0	0	0	110.9	I159 M162 A163 F166 V250 S251 L256 F257 V258	I159-I254 HydrophobicContact CG2-CD1 4.38Å; M162-I254 HydrophobicContact CB-CD1 4.07Å; A163-I254 HydrophobicContact CB-CD1 4.19Å; A163-I254 HydrophobicContact CB-CG1 4.25Å; F166-I254 HydrophobicContact CD2-CG2 3.71Å; F166-I254 HydrophobicContact CE2-CG2 4.27Å; V250-I254 HydrophobicContact CG1-CD1 4.02Å; V250-I254 WeakPolarHBondContact O-CG1 3.44Å; V250-I254 PolarHBondContact O-N 2.96Å; S251-I254 PolarHBondContact O-N 3.49Å; I254-L256 VanDerWaalsContact C-N 3.33Å; I254-L256 PolarHBondContact O-N 3.45Å; I254-F257 WeakPolarHBondContact O-CB 3.35Å; I254-F257 PolarHBondContact O-N 3.16Å; I254-V258 PolarHBondContact O-N 2.9Å
255	N	90.8	Very high	89.1	Confident	49 Å²	49	40.1 Å²	40.1	26%	0.262	23%	0.228	S	C	.	.	H	α-helix	trans	-65.3	-36.8	-179.9	-67.8	-22	0	0	0	112	L52 S251 F252 V258 M259	L52-N255 HydrophobicContact CD1-CB 3.86Å; L52-N255 HydrophobicContact CD2-CB 4.05Å; L52-N255 HydrophobicContact CG-CB 4.39Å; S251-N255 WeakPolarHBondContact O-CB 3.5Å; S251-N255 VanDerWaalsContact O-CG 3.26Å; S251-N255 PolarHBondContact O-N 3.01Å; S251-N255 PolarHBondContact O-ND2 3.37Å; F252-N255 PolarHBondContact O-N 3.23Å; N255-V258 PolarHBondContact O-N 3.09Å; N255-M259 WeakPolarHBondContact O-CB 3.47Å; N255-M259 VanDerWaalsContact O-CG 3.25Å; N255-M259 WeakPolarHBondContact O-CG 3.36Å; N255-M259 PolarHBondContact O-N 2.8Å
256	L	90	Very high	88.3	Confident	30 Å²	30	37.9 Å²	37.9	16%	0.157	22%	0.215	C	C	.	.	H	α-helix	trans	-61.8	-43.3	173.2	173.6	62	0	0	0	111.3	L49 L52 L184 F252 I253 I254 A260	L49-L256 HydrophobicContact CD2-CD1 3.47Å; L49-L256 VanDerWaalsContact CD2-CD1 3.47Å; L52-L256 HydrophobicContact CD2-CB 4.35Å; L184-L256 HydrophobicContact CD1-CD1 4.39Å; F252-L256 HydrophobicContact CE1-CD2 4.34Å; F252-L256 HydrophobicContact CZ-CD2 4.41Å; F252-L256 WeakPolarHBondContact O-CB 3.19Å; F252-L256 PolarHBondContact O-N 3.48Å; I253-L256 PolarHBondContact O-N 3.29Å; I254-L256 VanDerWaalsContact C-N 3.33Å; I254-L256 PolarHBondContact O-N 3.45Å; L256-A260 WeakPolarHBondContact O-CB 3.49Å; L256-A260 PolarHBondContact O-N 2.9Å
257	F	90.7	Very high	87.3	Confident	41 Å²	41	38.2 Å²	38.2	18%	0.18	21%	0.21	C	C	.	.	H	α-helix	trans	-61.5	-50.6	175.4	-68.5	-16.2	0	0	0	111.7	F166 Y170 I253 I254 M259 A260 V261	F166-F257 HydrophobicContact CB-CB 4.41Å; Y170-F257 AromaticContact CD1-CD1 3.72Å; Y170-F257 HydrophobicContact CD1-CD1 3.72Å; Y170-F257 AromaticContact CD1-CE1 3.65Å; Y170-F257 HydrophobicContact CD1-CE1 3.65Å; Y170-F257 HydrophobicContact CD1-CZ 4.4Å; Y170-F257 HydrophobicContact CD2-CB 4.2Å; Y170-F257 AromaticContact CD2-CD1 3.5Å; Y170-F257 HydrophobicContact CD2-CD1 3.5Å; Y170-F257 HydrophobicContact CD2-CE1 4.24Å; Y170-F257 HydrophobicContact CD2-CG 4.15Å; Y170-F257 HydrophobicContact CE1-CD1 4.11Å; Y170-F257 AromaticContact CE1-CE1 3.86Å; Y170-F257 HydrophobicContact CE1-CE1 3.86Å; Y170-F257 AromaticContact CE2-CD1 3.88Å; Y170-F257 HydrophobicContact CE2-CD1 3.88Å; Y170-F257 HydrophobicContact CE2-CE1 4.4Å; Y170-F257 HydrophobicContact CG-CB 4.28Å; Y170-F257 AromaticContact CG-CD1 3.39Å; Y170-F257 HydrophobicContact CG-CD1 3.39Å; Y170-F257 AromaticContact CG-CE1 3.84Å; Y170-F257 HydrophobicContact CG-CE1 3.84Å; Y170-F257 AromaticContact CG-CG 3.93Å; Y170-F257 HydrophobicContact CG-CG 3.93Å; I253-F257 HydrophobicContact CG2-CD1 4.46Å; I253-F257 HydrophobicContact CG2-CD2 4.11Å; I253-F257 HydrophobicContact CG2-CE1 3.94Å; I253-F257 HydrophobicContact CG2-CE2 3.54Å; I253-F257 HydrophobicContact CG2-CZ 3.45Å; I253-F257 VanDerWaalsContact CG2-CZ 3.45Å; I253-F257 VanDerWaalsContact O-CG 3.24Å; I253-F257 WeakPolarHBondContact O-CG 3.38Å; I253-F257 PolarHBondContact O-N 2.88Å; I254-F257 WeakPolarHBondContact O-CB 3.35Å; I254-F257 PolarHBondContact O-N 3.16Å; F257-M259 PolarHBondContact O-N 2.78Å; F257-A260 PolarHBondContact O-N 3.43Å; F257-V261 WeakPolarHBondContact O-CB 3.25Å; F257-V261 VanDerWaalsContact O-CG2 3.22Å; F257-V261 WeakPolarHBondContact O-CG2 3.19Å; F257-V261 PolarHBondContact O-N 3.47Å
258	V	88.7	Confident	86.2	Confident	30 Å²	30	42.4 Å²	42.4	18%	0.182	22%	0.22	C	C	.	.	H	α-helix	trans	-59.1	-48.9	178.6	172.3	0	0	0	0	111.4	F166 I254 N255 A260 V261 F262 W320	F166-V258 HydrophobicContact CB-CG2 4.14Å; F166-V258 HydrophobicContact CD1-CG2 3.87Å; F166-V258 HydrophobicContact CD2-CG2 4.1Å; F166-V258 HydrophobicContact CE1-CG2 4.27Å; F166-V258 HydrophobicContact CE2-CG2 4.47Å; F166-V258 HydrophobicContact CG-CG2 3.78Å; I254-V258 PolarHBondContact O-N 2.9Å; N255-V258 PolarHBondContact O-N 3.09Å; V258-A260 PolarHBondContact O-N 2.99Å; V258-V261 PolarHBondContact O-N 2.76Å; V258-F262 HydrophobicContact CG1-CD2 4.45Å; V258-F262 WeakPolarHBondContact O-CB 3.46Å; V258-F262 PolarHBondContact O-N 2.9Å; V258-W320 HydrophobicContact CG1-CH2 3.96Å; V258-W320 HydrophobicContact CG1-CZ3 4.36Å; V258-W320 HydrophobicContact CG2-CZ3 4.35Å
259	M	85.6	Confident	85.5	Confident	46 Å²	46	44.1 Å²	44.1	23%	0.227	23%	0.227	C	C	.	.	H	α-helix	trans	-62.8	-39	179	-72.5	-62.2	-61	0	0	112.7	L49 L52 N255 F257 G263	L49-M259 HydrophobicContact CD2-CB 4.29Å; L52-M259 HydrophobicContact CD1-CG 4.41Å; N255-M259 WeakPolarHBondContact O-CB 3.47Å; N255-M259 VanDerWaalsContact O-CG 3.25Å; N255-M259 WeakPolarHBondContact O-CG 3.36Å; N255-M259 PolarHBondContact O-N 2.8Å; F257-M259 PolarHBondContact O-N 2.78Å; M259-G263 PolarHBondContact O-N 2.89Å
260	A	86.1	Confident	84.9	Confident	3 Å²	3	43 Å²	43	3%	0.025	22%	0.218	C	C	.	.	H	α-helix	trans	-70	-40.8	177.8	0	0	0	0	0	112.7	Y170 P175 L180 L256 F257 V258 G263 Q264	Y170-A260 HydrophobicContact CD2-CB 3.88Å; Y170-A260 HydrophobicContact CE2-CB 3.63Å; P175-A260 HydrophobicContact CB-CB 4.35Å; P175-A260 HydrophobicContact CG-CB 4.18Å; L180-A260 HydrophobicContact CD1-CB 3.86Å; L180-A260 HydrophobicContact CD2-CB 3.62Å; L180-A260 HydrophobicContact CG-CB 4.41Å; L256-A260 WeakPolarHBondContact O-CB 3.49Å; L256-A260 PolarHBondContact O-N 2.9Å; F257-A260 PolarHBondContact O-N 3.43Å; V258-A260 PolarHBondContact O-N 2.99Å; A260-G263 PolarHBondContact O-N 3.18Å; A260-Q264 WeakPolarHBondContact O-CB 3.23Å; A260-Q264 PolarHBondContact O-N 2.91Å
261	V	87.5	Confident	84.4	Confident	1 Å²	1	40.7 Å²	40.7	1%	0.006	20%	0.204	C	C	.	.	H	α-helix	trans	-64.7	-48.2	176.9	167.4	0	0	0	0	110.7	E169 Y170 A173 F257 V258 G263 Q264 A265 L308	E169-V261 HydrophobicContact CB-CG1 4.24Å; E169-V261 HydrophobicContact CB-CG2 3.99Å; Y170-V261 VanDerWaalsContact CA-CG2 3.47Å; A173-V261 HydrophobicContact CB-CG2 4.15Å; F257-V261 WeakPolarHBondContact O-CB 3.25Å; F257-V261 VanDerWaalsContact O-CG2 3.22Å; F257-V261 WeakPolarHBondContact O-CG2 3.19Å; F257-V261 PolarHBondContact O-N 3.47Å; V258-V261 PolarHBondContact O-N 2.76Å; V261-G263 VanDerWaalsContact C-N 3.34Å; V261-G263 PolarHBondContact O-N 3.36Å; V261-Q264 PolarHBondContact O-N 3.47Å; V261-A265 VanDerWaalsContact O-CB 3.3Å; V261-A265 WeakPolarHBondContact O-CB 3.43Å; V261-A265 PolarHBondContact O-N 3.43Å; V261-L308 HydrophobicContact CG1-CD1 3.73Å; V261-L308 HydrophobicContact CG1-CD2 3.43Å; V261-L308 VanDerWaalsContact CG1-CD2 3.43Å; V261-L308 HydrophobicContact CG1-CG 4.22Å
262	F	84.5	Confident	84.1	Confident	26 Å²	26	42.7 Å²	42.7	11%	0.114	21%	0.208	C	C	.	.	H	α-helix	trans	-65.4	-37.5	175.6	-81.4	6.6	0	0	0	112.3	V258 A265 F266 V299 L308 W320	V258-F262 HydrophobicContact CG1-CD2 4.45Å; V258-F262 WeakPolarHBondContact O-CB 3.46Å; V258-F262 PolarHBondContact O-N 2.9Å; F262-A265 PolarHBondContact O-N 3.29Å; F262-F266 HydrophobicContact CB-CD2 4.25Å; F262-F266 HydrophobicContact CD1-CE2 4.17Å; F262-F266 HydrophobicContact CE1-CE2 4.44Å; F262-F266 HydrophobicContact CG-CD2 4.4Å; F262-F266 HydrophobicContact CG-CE2 4.25Å; F262-F266 WeakPolarHBondContact O-CB 3.23Å; F262-F266 WeakPolarHBondContact O-CD2 3.33Å; F262-F266 PolarHBondContact O-N 3.3Å; F262-V299 HydrophobicContact CD2-CG1 3.7Å; F262-V299 HydrophobicContact CE2-CG1 4.06Å; F262-V299 HydrophobicContact CG-CG1 4.4Å; F262-L308 HydrophobicContact CE1-CD1 4.15Å; F262-W320 HydrophobicContact CD1-CH2 4.38Å; F262-W320 HydrophobicContact CE1-CE3 4.47Å; F262-W320 AromaticContact CE1-CH2 3.43Å; F262-W320 HydrophobicContact CE1-CH2 3.43Å; F262-W320 VanDerWaalsContact CE1-CH2 3.43Å; F262-W320 AromaticContact CE1-CZ2 3.77Å; F262-W320 HydrophobicContact CE1-CZ2 3.77Å; F262-W320 AromaticContact CE1-CZ3 3.81Å; F262-W320 HydrophobicContact CE1-CZ3 3.81Å; F262-W320 HydrophobicContact CE2-CH2 4.07Å; F262-W320 HydrophobicContact CE2-CZ2 4.27Å; F262-W320 AromaticContact CZ-CH2 3.25Å; F262-W320 HydrophobicContact CZ-CH2 3.25Å; F262-W320 AromaticContact CZ-CZ2 3.31Å; F262-W320 HydrophobicContact CZ-CZ2 3.31Å; F262-W320 HydrophobicContact CZ-CZ3 4.12Å
263	G	80.4	Confident	83.6	Confident	14 Å²	14	45.4 Å²	45.4	14%	0.144	22%	0.221	C	C	.	.	H	α-helix	trans	-53.7	-56.8	169.6	0	0	0	0	0	111.7	M259 A260 V261 A265 Y267	M259-G263 PolarHBondContact O-N 2.89Å; A260-G263 PolarHBondContact O-N 3.18Å; V261-G263 VanDerWaalsContact C-N 3.34Å; V261-G263 PolarHBondContact O-N 3.36Å; G263-A265 VanDerWaalsContact C-N 3.32Å; G263-A265 PolarHBondContact O-N 3.36Å; G263-Y267 WeakPolarHBondContact O-CB 3.28Å; G263-Y267 PolarHBondContact O-N 3.3Å
264	Q	82.4	Confident	83.2	Confident	96 Å²	96	41.8 Å²	41.8	45%	0.449	20%	0.203	S	C	.	.	H	α-helix	trans	-62	-36.6	-179.4	-170.5	66.6	29	0	0	113.2	P175 A260 V261	P175-Q264 HydrophobicContact CB-CB 4.3Å; A260-Q264 WeakPolarHBondContact O-CB 3.23Å; A260-Q264 PolarHBondContact O-N 2.91Å; V261-Q264 PolarHBondContact O-N 3.47Å
265	A	81.1	Confident	83	Confident	3 Å²	3	42.4 Å²	42.4	3%	0.025	21%	0.205	C	C	.	.	H	α-helix	trans	-78.6	-31.2	-176.1	0	0	0	0	0	114.3	V261 F262 G263 I307 L308 L311	V261-A265 VanDerWaalsContact O-CB 3.3Å; V261-A265 WeakPolarHBondContact O-CB 3.43Å; V261-A265 PolarHBondContact O-N 3.43Å; F262-A265 PolarHBondContact O-N 3.29Å; G263-A265 VanDerWaalsContact C-N 3.32Å; G263-A265 PolarHBondContact O-N 3.36Å; A265-I307 HydrophobicContact CB-CG2 4.17Å; A265-L308 HydrophobicContact CB-CD2 3.85Å; A265-L311 HydrophobicContact CB-CD1 4.04Å
266	F	77.3	Confident	82.8	Confident	3 Å²	3	44 Å²	44	1%	0.013	21%	0.214	C	C	.	.	H	α-helix	trans	-109.8	-6.8	-175.4	-68.4	-76.9	0	0	0	114.6	I42 F262 Q268 Q269 V297 V299 I307	I42-F266 HydrophobicContact CD1-CB 3.94Å; F262-F266 HydrophobicContact CB-CD2 4.25Å; F262-F266 HydrophobicContact CD1-CE2 4.17Å; F262-F266 HydrophobicContact CE1-CE2 4.44Å; F262-F266 HydrophobicContact CG-CD2 4.4Å; F262-F266 HydrophobicContact CG-CE2 4.25Å; F262-F266 WeakPolarHBondContact O-CB 3.23Å; F262-F266 WeakPolarHBondContact O-CD2 3.33Å; F262-F266 PolarHBondContact O-N 3.3Å; F266-Q268 PolarHBondContact O-N 2.88Å; F266-Q268 VanDerWaalsContact O-N 3.09Å; F266-Q269 PolarHBondContact O-N 3.1Å; F266-V297 HydrophobicContact CD1-CB 4.07Å; F266-V297 HydrophobicContact CD1-CG1 3.86Å; F266-V297 HydrophobicContact CE1-CB 4.33Å; F266-V297 HydrophobicContact CE1-CG1 3.61Å; F266-V299 HydrophobicContact CB-CG2 4.08Å; F266-V299 HydrophobicContact CD1-CG2 4.32Å; F266-V299 HydrophobicContact CD2-CG1 4.07Å; F266-V299 HydrophobicContact CD2-CG2 3.98Å; F266-V299 HydrophobicContact CE2-CG1 3.96Å; F266-V299 HydrophobicContact CE2-CG2 4.46Å; F266-V299 HydrophobicContact CG-CG2 3.9Å; F266-I307 HydrophobicContact CE1-CB 4.43Å; F266-I307 HydrophobicContact CE1-CG2 3.84Å; F266-I307 HydrophobicContact CE2-CG2 3.84Å; F266-I307 HydrophobicContact CZ-CB 4.4Å; F266-I307 HydrophobicContact CZ-CG2 3.46Å; F266-I307 VanDerWaalsContact CZ-CG2 3.46Å
267	Y	72	Confident	82.7	Confident	112 Å²	112	45.1 Å²	45.1	44%	0.439	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-60	117.6	-175.5	-171.8	-117.4	0	0	0	112.5	G263 Q269	G263-Y267 WeakPolarHBondContact O-CB 3.28Å; G263-Y267 PolarHBondContact O-N 3.3Å; Y267-Q269 PolarHBondContact O-N 3.25Å; Y267-Q269 VanDerWaalsContact O-N 3.11Å
268	Q	66.9	Low	82.5	Confident	145 Å²	145	43.1 Å²	43.1	68%	0.678	21%	0.21	S	C	*	.	T	Hydrogen-bonded Turn	trans	58.2	13.6	-178.8	-60.2	-174.5	-24.9	0	0	115.8	F266	F266-Q268 PolarHBondContact O-N 2.88Å; F266-Q268 VanDerWaalsContact O-N 3.09Å
269	Q	74.7	Confident	82.4	Confident	53 Å²	53	43.6 Å²	43.6	25%	0.248	22%	0.217	C	C	.	.			trans	-76.9	128.4	178.4	-66.2	-67.8	-35.4	0	0	111.9	F266 Y267 V297	F266-Q269 PolarHBondContact O-N 3.1Å; Y267-Q269 PolarHBondContact O-N 3.25Å; Y267-Q269 VanDerWaalsContact O-N 3.11Å; Q269-V297 PolarHBondContact O-N 3.44Å
270	T	82.8	Confident	82.5	Confident	31 Å²	31	48.7 Å²	48.7	19%	0.19	25%	0.245	C	C	.	.	B	Isolated β-bridge	trans	-83	159.4	167.7	63.3	0	0	0	0	111.4	E272 E273 A274 N295	T270-E272 PolarHBondContact O-N 3.02Å; T270-E273 WeakPolarHBondContact CB-OE2 3.25Å; T270-E273 WeakPolarHBondContact CG2-OE2 3.33Å; T270-E273 PolarHBondContact N-OE2 2.91Å; T270-E273 PolarHBondContact O-N 3.32Å; T270-E273 VanDerWaalsContact OG1-CD 3.22Å; T270-E273 VanDerWaalsContact OG1-CG 3.27Å; T270-E273 WeakPolarHBondContact OG1-CG 3.45Å; T270-E273 PolarHBondContact OG1-N 2.69Å; T270-E273 PolarHBondContact OG1-OE2 3.2Å; T270-A274 PolarHBondContact O-N 2.97Å; T270-A274 VanDerWaalsContact O-N 3.07Å; T270-N295 WeakPolarHBondContact CA-O 3.36Å
271	N	82.8	Confident	82.5	Confident	3 Å²	3	49.7 Å²	49.7	2%	0.016	25%	0.252	C	S	.	.	H	α-helix	trans	-66.4	-27.2	177.6	-62.1	-94	0	0	0	112.6	F275 P291 N295 T296 V297	N271-F275 WeakPolarHBondContact O-CB 3.23Å; N271-F275 PolarHBondContact O-N 3.47Å; N271-P291 HydrophobicContact CB-CG 4.36Å; N271-P291 WeakPolarHBondContact CB-O 3.47Å; N271-N295 PolarHBondContact N-O 3.48Å; N271-N295 PolarHBondContact ND2-O 3.34Å; N271-T296 VanDerWaalsContact ND2-C 3.28Å; N271-T296 PolarHBondContact ND2-O 3.18Å; N271-V297 HydrophobicContact CB-CG2 4.27Å
272	E	83.3	Confident	82.3	Confident	90 Å²	90	54.9 Å²	54.9	42%	0.421	29%	0.289	S	S	.	.	H	α-helix	trans	-69.7	-42.3	173.9	-176.1	167.7	-175.7	0	0	112.3	T270 F275 N276	T270-E272 PolarHBondContact O-N 3.02Å; E272-F275 WeakPolarHBondContact O-CB 3.2Å; E272-F275 PolarHBondContact O-N 3.34Å; E272-N276 WeakPolarHBondContact O-CB 3.45Å; E272-N276 VanDerWaalsContact O-CG 3.24Å; E272-N276 PolarHBondContact O-N 2.98Å; E272-N276 PolarHBondContact O-ND2 3.21Å; E272-N276 VanDerWaalsContact O-ND2 3.16Å
273	E	83.8	Confident	82.3	Confident	88 Å²	88	54.4 Å²	54.4	41%	0.411	29%	0.287	S	S	.	.	H	α-helix	trans	-62.5	-47.2	174.3	-71.7	160.9	140.6	0	0	111.4	T270 F275 N276 I277	T270-E273 WeakPolarHBondContact CB-OE2 3.25Å; T270-E273 WeakPolarHBondContact CG2-OE2 3.33Å; T270-E273 PolarHBondContact N-OE2 2.91Å; T270-E273 PolarHBondContact O-N 3.32Å; T270-E273 VanDerWaalsContact OG1-CD 3.22Å; T270-E273 VanDerWaalsContact OG1-CG 3.27Å; T270-E273 WeakPolarHBondContact OG1-CG 3.45Å; T270-E273 PolarHBondContact OG1-N 2.69Å; T270-E273 PolarHBondContact OG1-OE2 3.2Å; E273-F275 VanDerWaalsContact C-N 3.33Å; E273-F275 PolarHBondContact O-N 2.99Å; E273-N276 PolarHBondContact O-N 3.33Å; E273-N276 VanDerWaalsContact O-N 3.13Å; E273-I277 VanDerWaalsContact O-CG1 3.28Å; E273-I277 WeakPolarHBondContact O-CG1 3.26Å; E273-I277 PolarHBondContact O-N 2.91Å
274	A	83.9	Confident	82.4	Confident	1 Å²	1	60 Å²	60	1%	0.008	31%	0.309	C	S	.	.	H	α-helix	trans	-58.3	-42.6	175.1	0	0	0	0	0	112.5	T270 C278 F290 V297 I307	T270-A274 PolarHBondContact O-N 2.97Å; T270-A274 VanDerWaalsContact O-N 3.07Å; A274-C278 WeakPolarHBondContact O-CB 3.34Å; A274-C278 PolarHBondContact O-N 2.97Å; A274-C278 VanDerWaalsContact O-N 3.08Å; A274-F290 HydrophobicContact CB-CB 4.46Å; A274-F290 HydrophobicContact CB-CD1 3.86Å; A274-F290 HydrophobicContact CB-CD2 4.37Å; A274-F290 HydrophobicContact CB-CE1 4.21Å; A274-F290 HydrophobicContact CB-CG 3.95Å; A274-V297 HydrophobicContact CB-CG2 3.93Å; A274-I307 HydrophobicContact CB-CD1 3.9Å
275	F	87.1	Confident	82.4	Confident	26 Å²	26	61.6 Å²	61.6	11%	0.114	32%	0.321	C	S	.	.	H	α-helix	trans	-58.5	-48.8	173.4	-178.2	-77.5	0	0	0	111.3	N271 E272 E273 C278 A279 A287 F290 R292	N271-F275 WeakPolarHBondContact O-CB 3.23Å; N271-F275 PolarHBondContact O-N 3.47Å; E272-F275 WeakPolarHBondContact O-CB 3.2Å; E272-F275 PolarHBondContact O-N 3.34Å; E273-F275 VanDerWaalsContact C-N 3.33Å; E273-F275 PolarHBondContact O-N 2.99Å; F275-C278 PolarHBondContact O-N 3.34Å; F275-A279 HydrophobicContact CD1-CB 4.28Å; F275-A279 HydrophobicContact CE1-CB 3.88Å; F275-A279 VanDerWaalsContact O-CB 3.26Å; F275-A279 WeakPolarHBondContact O-CB 3.38Å; F275-A279 PolarHBondContact O-N 3.11Å; F275-A287 HydrophobicContact CD2-CB 4.13Å; F275-A287 WeakPolarHBondContact CD2-O 3.33Å; F275-A287 HydrophobicContact CE1-CB 4.43Å; F275-A287 HydrophobicContact CE2-CB 3.86Å; F275-A287 WeakPolarHBondContact CE2-O 3.23Å; F275-A287 HydrophobicContact CZ-CB 3.99Å; F275-F290 HydrophobicContact CB-CB 4.24Å; F275-R292 HydrophobicContact CD2-CG 4.15Å; F275-R292 HydrophobicContact CG-CG 4.21Å
276	N	87.3	Confident	82.5	Confident	82 Å²	82	62.8 Å²	62.8	44%	0.439	33%	0.325	S	S	.	.	H	α-helix	trans	-67.2	-39.7	-175.4	-72.6	-29.9	0	0	0	112.3	E272 E273 A279 N280	E272-N276 WeakPolarHBondContact O-CB 3.45Å; E272-N276 VanDerWaalsContact O-CG 3.24Å; E272-N276 PolarHBondContact O-N 2.98Å; E272-N276 PolarHBondContact O-ND2 3.21Å; E272-N276 VanDerWaalsContact O-ND2 3.16Å; E273-N276 PolarHBondContact O-N 3.33Å; E273-N276 VanDerWaalsContact O-N 3.13Å; N276-A279 PolarHBondContact O-N 3.32Å; N276-N280 PolarHBondContact O-N 3Å; N276-N280 VanDerWaalsContact O-N 3.11Å
277	I	87.2	Confident	82.7	Confident	53 Å²	53	62.8 Å²	62.8	27%	0.272	33%	0.326	S	S	.	.	H	α-helix	trans	-59.7	-51.6	173	-68.3	163.4	0	0	0	110	E273 A279 N280 S281 C310 L311	E273-I277 VanDerWaalsContact O-CG1 3.28Å; E273-I277 WeakPolarHBondContact O-CG1 3.26Å; E273-I277 PolarHBondContact O-N 2.91Å; I277-A279 PolarHBondContact O-N 2.95Å; I277-N280 PolarHBondContact O-N 3.24Å; I277-S281 PolarHBondContact O-N 2.98Å; I277-C310 HydrophobicContact CG2-CB 4.14Å; I277-L311 HydrophobicContact CD1-CD2 4.25Å; I277-L311 HydrophobicContact CG2-CD2 3.86Å; I277-L311 HydrophobicContact CG2-CG 4.34Å
278	C	87.2	Confident	83.1	Confident	0 Å²	0	66.2 Å²	66.2	0%	0	34%	0.343	C	S	.	.	H	α-helix	trans	-64.1	-37.7	178.5	-75.7	0	0	0	0	113.3	A274 F275 N280 S281 Q284 A287 C310	A274-C278 WeakPolarHBondContact O-CB 3.34Å; A274-C278 PolarHBondContact O-N 2.97Å; A274-C278 VanDerWaalsContact O-N 3.08Å; F275-C278 PolarHBondContact O-N 3.34Å; C278-N280 VanDerWaalsContact C-N 3.33Å; C278-N280 PolarHBondContact O-N 3.41Å; C278-S281 PolarHBondContact O-N 2.89Å; C278-S281 PolarHBondContact O-OG 3.12Å; C278-Q284 WeakPolarHBondContact O-CA 3.4Å; C278-Q284 PolarHBondContact O-N 3.42Å; C278-A287 HydrophobicContact CB-CB 3.92Å; C278-C310 WeakPolarHBondContact CA-SG 3.39Å; C278-C310 HydrophobicContact CB-CB 3.96Å; C278-C310 WeakPolarHBondContact CB-SG 3.46Å; C278-C310 WeakPolarHBondContact SG-CB 3.32Å; C278-C310 CovalentContact SG-SG 2.04Å; C278-C310 PolarHBondContact SG-SG 3.44Å
279	A	87.8	Confident	83.8	Confident	39 Å²	39	61 Å²	61	32%	0.322	32%	0.319	S	S	.	.	H	α-helix	trans	-67.1	-31.2	179.5	0	0	0	0	0	113.3	F275 N276 I277 S281 A287	F275-A279 HydrophobicContact CD1-CB 4.28Å; F275-A279 HydrophobicContact CE1-CB 3.88Å; F275-A279 VanDerWaalsContact O-CB 3.26Å; F275-A279 WeakPolarHBondContact O-CB 3.38Å; F275-A279 PolarHBondContact O-N 3.11Å; N276-A279 PolarHBondContact O-N 3.32Å; I277-A279 PolarHBondContact O-N 2.95Å; A279-S281 VanDerWaalsContact C-N 3.35Å; A279-A287 HydrophobicContact CB-CB 4.1Å
280	N	87.1	Confident	84.1	Confident	153 Å²	153	58.6 Å²	58.6	82%	0.818	31%	0.308	S	S	*	.	H	α-helix	trans	-86.4	-6.4	175.6	-162.3	29	0	0	0	113.2	N276 I277 C278	N276-N280 PolarHBondContact O-N 3Å; N276-N280 VanDerWaalsContact O-N 3.11Å; I277-N280 PolarHBondContact O-N 3.24Å; C278-N280 VanDerWaalsContact C-N 3.33Å; C278-N280 PolarHBondContact O-N 3.41Å
281	S	86.6	Confident	83.9	Confident	24 Å²	24	58.7 Å²	58.7	17%	0.168	31%	0.31	C	S	.	.	S	Bend	trans	-89.8	167.2	178.9	81.9	0	0	0	0	112.4	I277 C278 A279 L283 Q284	I277-S281 PolarHBondContact O-N 2.98Å; C278-S281 PolarHBondContact O-N 2.89Å; C278-S281 PolarHBondContact O-OG 3.12Å; A279-S281 VanDerWaalsContact C-N 3.35Å; S281-L283 PolarHBondContact O-N 3.5Å; S281-L283 PolarHBondContact OG-N 3Å; S281-Q284 PolarHBondContact O-N 3.35Å
282	S	83.1	Confident	83.7	Confident	111 Å²	111	66.9 Å²	66.9	78%	0.776	34%	0.34	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.7	-10.4	169.7	-51.5	0	0	0	0	114
283	L	84.3	Confident	83.5	Confident	15 Å²	15	65.5 Å²	65.5	8%	0.079	34%	0.335	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.5	23.1	-180	-70.4	81.4	0	0	0	113.1	S281 N285 Y286 G309 P314 L317	S281-L283 PolarHBondContact O-N 3.5Å; S281-L283 PolarHBondContact OG-N 3Å; L283-N285 PolarHBondContact O-N 3.43Å; L283-Y286 HydrophobicContact CB-CD2 4Å; L283-Y286 HydrophobicContact CD2-CD2 4.26Å; L283-Y286 HydrophobicContact CG-CD2 4.4Å; L283-Y286 WeakPolarHBondContact O-CB 3.36Å; L283-Y286 PolarHBondContact O-N 3.21Å; L283-G309 WeakPolarHBondContact CD1-O 3.47Å; L283-P314 HydrophobicContact CD1-CB 4.21Å; L283-P314 HydrophobicContact CD1-CG 3.71Å; L283-L317 HydrophobicContact CD2-CB 4.44Å; L283-L317 HydrophobicContact CD2-CD1 3.46Å; L283-L317 VanDerWaalsContact CD2-CD1 3.46Å
284	Q	81.8	Confident	83.3	Confident	131 Å²	131	67.8 Å²	67.8	61%	0.612	35%	0.351	S	S	*	.	G	3₁₀ helix	trans	-40.7	-32.2	-179.8	60.8	175.4	-21	0	0	116.5	C278 S281 Y286 A287	C278-Q284 WeakPolarHBondContact O-CA 3.4Å; C278-Q284 PolarHBondContact O-N 3.42Å; S281-Q284 PolarHBondContact O-N 3.35Å; Q284-Y286 PolarHBondContact O-N 2.73Å; Q284-A287 WeakPolarHBondContact O-CB 3.33Å; Q284-A287 PolarHBondContact O-N 3.28Å
285	N	83.2	Confident	83.1	Confident	131 Å²	131	71.4 Å²	71.4	70%	0.701	37%	0.37	S	S	*	.	G	3₁₀ helix	trans	-59.8	-32.3	176.6	-68.8	-24.2	0	0	0	113.2	L283	L283-N285 PolarHBondContact O-N 3.43Å
286	Y	82.9	Confident	82.3	Confident	28 Å²	28	72.3 Å²	72.3	11%	0.11	38%	0.377	C	S	.	.	G	3₁₀ helix	trans	-83	-14.4	-178	-69.5	-89.6	0	0	0	113.7	A121 L283 Q284 K288 I289 V306	A121-Y286 WeakPolarHBondContact CA-OH 3.36Å; L283-Y286 HydrophobicContact CB-CD2 4Å; L283-Y286 HydrophobicContact CD2-CD2 4.26Å; L283-Y286 HydrophobicContact CG-CD2 4.4Å; L283-Y286 WeakPolarHBondContact O-CB 3.36Å; L283-Y286 PolarHBondContact O-N 3.21Å; Q284-Y286 PolarHBondContact O-N 2.73Å; Y286-K288 PolarHBondContact O-N 2.98Å; Y286-I289 HydrophobicContact CD1-CD1 3.65Å; Y286-I289 HydrophobicContact CG-CD1 4.4Å; Y286-I289 WeakPolarHBondContact O-CB 3.49Å; Y286-I289 WeakPolarHBondContact O-CG1 3.42Å; Y286-I289 PolarHBondContact O-N 3.34Å; Y286-V306 HydrophobicContact CD1-CG1 4.32Å; Y286-V306 HydrophobicContact CD1-CG2 3.82Å; Y286-V306 HydrophobicContact CE1-CG2 4.4Å; Y286-V306 HydrophobicContact CG-CG1 4.27Å
287	A	80.6	Confident	81.6	Confident	3 Å²	3	68.5 Å²	68.5	3%	0.025	36%	0.357	C	S	.	.	G	3₁₀ helix	trans	-54.6	-32.1	-179	0	0	0	0	0	112.6	F275 C278 A279 Q284 I289 F290	F275-A287 HydrophobicContact CD2-CB 4.13Å; F275-A287 WeakPolarHBondContact CD2-O 3.33Å; F275-A287 HydrophobicContact CE1-CB 4.43Å; F275-A287 HydrophobicContact CE2-CB 3.86Å; F275-A287 WeakPolarHBondContact CE2-O 3.23Å; F275-A287 HydrophobicContact CZ-CB 3.99Å; C278-A287 HydrophobicContact CB-CB 3.92Å; A279-A287 HydrophobicContact CB-CB 4.1Å; Q284-A287 WeakPolarHBondContact O-CB 3.33Å; Q284-A287 PolarHBondContact O-N 3.28Å; A287-I289 PolarHBondContact O-N 3.49Å; A287-F290 PolarHBondContact O-N 3.48Å; A287-F290 VanDerWaalsContact O-N 3.14Å
288	K	81.6	Confident	80.7	Confident	183 Å²	183	69.1 Å²	69.1	80%	0.796	37%	0.366	S	S	*	.	G	3₁₀ helix	trans	-59.4	-15.1	177.9	-62	178.7	-177.8	175.4	0	115.2	Y286 F290	Y286-K288 PolarHBondContact O-N 2.98Å; K288-F290 VanDerWaalsContact C-N 3.33Å
289	I	80.4	Confident	80	Confident	35 Å²	35	72 Å²	72	18%	0.179	38%	0.384	C	S	.	.	G	3₁₀ helix	trans	-73.6	-28.5	178.4	-66	162.7	0	0	0	111.2	Y286 A287 Y302 Q303 V306	Y286-I289 HydrophobicContact CD1-CD1 3.65Å; Y286-I289 HydrophobicContact CG-CD1 4.4Å; Y286-I289 WeakPolarHBondContact O-CB 3.49Å; Y286-I289 WeakPolarHBondContact O-CG1 3.42Å; Y286-I289 PolarHBondContact O-N 3.34Å; A287-I289 PolarHBondContact O-N 3.49Å; I289-Y302 HydrophobicContact CD1-CE1 3.59Å; I289-Y302 HydrophobicContact CG1-CE1 4.15Å; I289-Y302 HydrophobicContact CG2-CD1 4.4Å; I289-Y302 HydrophobicContact CG2-CE1 4.15Å; I289-Q303 HydrophobicContact CG2-CG 3.99Å; I289-V306 HydrophobicContact CD1-CG1 4.45Å; I289-V306 HydrophobicContact CD1-CG2 4Å
290	F	81.6	Confident	79.5	Confident	3 Å²	3	70.8 Å²	70.8	1%	0.013	37%	0.372	C	S	.	.	S	Bend	trans	-89.5	116.3	176.5	-58.3	-76	0	0	0	109.3	A274 F275 A287 K288 V297 Q303 V306 I307	A274-F290 HydrophobicContact CB-CB 4.46Å; A274-F290 HydrophobicContact CB-CD1 3.86Å; A274-F290 HydrophobicContact CB-CD2 4.37Å; A274-F290 HydrophobicContact CB-CE1 4.21Å; A274-F290 HydrophobicContact CB-CG 3.95Å; F275-F290 HydrophobicContact CB-CB 4.24Å; A287-F290 PolarHBondContact O-N 3.48Å; A287-F290 VanDerWaalsContact O-N 3.14Å; K288-F290 VanDerWaalsContact C-N 3.33Å; F290-V297 HydrophobicContact CD1-CG1 4.07Å; F290-V297 HydrophobicContact CE1-CG1 3.93Å; F290-Q303 HydrophobicContact CE1-CB 4.18Å; F290-Q303 HydrophobicContact CZ-CB 4.47Å; F290-V306 HydrophobicContact CE2-CG1 3.82Å; F290-V306 HydrophobicContact CZ-CG1 4.23Å; F290-I307 HydrophobicContact CZ-CB 4.16Å; F290-I307 HydrophobicContact CZ-CD1 4.25Å
291	P	79.3	Confident	79.3	Confident	34 Å²	34	65.6 Å²	65.6	22%	0.221	34%	0.344	C	S	.	.			trans	-67.4	144.5	175.7	29.4	-34.1	0	0	0	109.8	N271 D293	N271-P291 HydrophobicContact CB-CG 4.36Å; N271-P291 WeakPolarHBondContact CB-O 3.47Å; P291-D293 PolarHBondContact O-N 3.25Å
292	R	77.8	Confident	79.3	Confident	175 Å²	175	65.5 Å²	65.5	66%	0.66	34%	0.34	S	S	*	.	S	Bend	trans	-79.5	67	177.7	-67.1	-174.8	-178.8	176.6	-2.7	111.6	F275	F275-R292 HydrophobicContact CD2-CG 4.15Å; F275-R292 HydrophobicContact CG-CG 4.21Å
293	D	79.9	Confident	79.4	Confident	60 Å²	60	60.9 Å²	60.9	32%	0.321	31%	0.306	S	S	.	.			trans	-113.2	144.4	176.5	-64.9	-7.8	0	0	0	110.5	K39 P291 N295	K39-D293 IonicContact NZ-OD2 3.16Å; K39-D293 PolarHBondContact NZ-OD2 3.25Å; P291-D293 PolarHBondContact O-N 3.25Å; D293-N295 HydrophobicContact CB-CB 4.19Å; D293-N295 PolarHBondContact O-N 3.07Å; D293-N295 PolarHBondContact OD2-ND2 3.44Å
294	N	79.8	Confident	79.4	Confident	137 Å²	137	60.1 Å²	60.1	73%	0.733	30%	0.302	S	S	*	.	S	Bend	trans	-73.7	12.5	170.7	-119.2	1.8	0	0	0	114.2
295	N	78.7	Confident	79.7	Confident	76 Å²	76	53.9 Å²	53.9	41%	0.406	27%	0.273	S	S	.	.	S	Bend	trans	-81.1	160.2	175.8	-67.3	-59.7	0	0	0	110.3	K39 T270 N271 D293	K39-N295 HydrophobicContact CD-CB 3.72Å; K39-N295 PolarHBondContact NZ-ND2 3.29Å; T270-N295 WeakPolarHBondContact CA-O 3.36Å; N271-N295 PolarHBondContact N-O 3.48Å; N271-N295 PolarHBondContact ND2-O 3.34Å; D293-N295 HydrophobicContact CB-CB 4.19Å; D293-N295 PolarHBondContact O-N 3.07Å; D293-N295 PolarHBondContact OD2-ND2 3.44Å
296	T	71.4	Confident	80	Confident	45 Å²	45	47.7 Å²	47.7	28%	0.276	24%	0.24	S	C	.	.	B	Isolated β-bridge	trans	-61.4	149.7	166.4	45.9	0	0	0	0	111.2	N271	N271-T296 VanDerWaalsContact ND2-C 3.28Å; N271-T296 PolarHBondContact ND2-O 3.18Å
297	V	71.5	Confident	80.2	Confident	2 Å²	2	46.4 Å²	46.4	1%	0.012	24%	0.235	C	C	.	.	P	Polyproline II helix	trans	-70	134.6	175.2	-176.2	0	0	0	0	109.9	F266 Q269 N271 A274 F290	F266-V297 HydrophobicContact CD1-CB 4.07Å; F266-V297 HydrophobicContact CD1-CG1 3.86Å; F266-V297 HydrophobicContact CE1-CB 4.33Å; F266-V297 HydrophobicContact CE1-CG1 3.61Å; Q269-V297 PolarHBondContact O-N 3.44Å; N271-V297 HydrophobicContact CB-CG2 4.27Å; A274-V297 HydrophobicContact CB-CG2 3.93Å; F290-V297 HydrophobicContact CD1-CG1 4.07Å; F290-V297 HydrophobicContact CE1-CG1 3.93Å
298	S	69	Low	80.6	Confident	67 Å²	67	46.3 Å²	46.3	47%	0.469	23%	0.234	S	C	.	.	P	Polyproline II helix	trans	-69.7	128.8	167.2	45.7	0	0	0	0	109.7	D300 Q303	S298-D300 PolarHBondContact O-N 3.08Å; S298-Q303 PolarHBondContact O-OE1 2.96Å; S298-Q303 PolarHBondContact OG-OE1 3.02Å
299	V	71.3	Confident	81	Confident	59 Å²	59	37.6 Å²	37.6	36%	0.358	20%	0.196	S	C	.	.	P	Polyproline II helix	trans	-82.4	118	175.8	-176	0	0	0	0	108.9	I42 F262 F266	I42-V299 HydrophobicContact CD1-CG2 3.6Å; I42-V299 HydrophobicContact CG1-CG2 4.14Å; F262-V299 HydrophobicContact CD2-CG1 3.7Å; F262-V299 HydrophobicContact CE2-CG1 4.06Å; F262-V299 HydrophobicContact CG-CG1 4.4Å; F266-V299 HydrophobicContact CB-CG2 4.08Å; F266-V299 HydrophobicContact CD1-CG2 4.32Å; F266-V299 HydrophobicContact CD2-CG1 4.07Å; F266-V299 HydrophobicContact CD2-CG2 3.98Å; F266-V299 HydrophobicContact CE2-CG1 3.96Å; F266-V299 HydrophobicContact CE2-CG2 4.46Å; F266-V299 HydrophobicContact CG-CG2 3.9Å
300	D	78.4	Confident	81.5	Confident	15 Å²	15	36.5 Å²	36.5	8%	0.08	19%	0.191	C	C	.	.			trans	-137.6	156.8	172.1	173.2	46.9	0	0	0	110.1	S298 Y302 Q303 G304 S381	S298-D300 PolarHBondContact O-N 3.08Å; D300-Y302 VanDerWaalsContact C-N 3.27Å; D300-Y302 PolarHBondContact O-N 3.47Å; D300-Y302 VanDerWaalsContact OD2-CB 3.32Å; D300-Y302 WeakPolarHBondContact OD2-CB 3.39Å; D300-Y302 PolarHBondContact OD2-N 3.18Å; D300-Y302 VanDerWaalsContact OD2-N 3.16Å; D300-Q303 HydrophobicContact CB-CB 4.44Å; D300-Q303 HydrophobicContact CB-CG 4.45Å; D300-Q303 PolarHBondContact O-N 3.35Å; D300-G304 WeakPolarHBondContact O-CA 3.48Å; D300-G304 PolarHBondContact O-N 3.35Å; D300-S381 WeakPolarHBondContact OD1-CB 3.46Å; D300-S381 PolarHBondContact OD1-OG 2.87Å; D300-S381 PolarHBondContact OD2-OG 3.34Å
301	I	82.9	Confident	81.8	Confident	44 Å²	44	39.7 Å²	39.7	23%	0.226	21%	0.208	C	C	.	.	H	α-helix	trans	-57.9	-37.2	178.9	-58.6	178	0	0	0	111.8	I114 G305 W320 L324	I114-I301 HydrophobicContact CG2-CG2 4.4Å; I301-G305 PolarHBondContact O-N 2.65Å; I301-W320 HydrophobicContact CG2-CZ2 4.16Å; I301-W320 PolarHBondContact O-NE1 3.19Å; I301-W320 VanDerWaalsContact O-NE1 3.14Å; I301-L324 HydrophobicContact CG2-CD1 3.62Å; I301-L324 HydrophobicContact CG2-CD2 3.47Å; I301-L324 VanDerWaalsContact CG2-CD2 3.47Å; I301-L324 HydrophobicContact CG2-CG 4.19Å
302	Y	86.1	Confident	82.2	Confident	21 Å²	21	41.3 Å²	41.3	8%	0.082	21%	0.212	C	C	.	.	H	α-helix	trans	-73.3	-51.2	176.7	-179.2	-117.9	0	0	0	111.9	I114 N117 L118 I289 D300 G304 G305 V306 L377	I114-Y302 HydrophobicContact CG2-CD2 4.04Å; N117-Y302 WeakPolarHBondContact OD1-CE2 2.99Å; N117-Y302 PolarHBondContact OD1-OH 2.94Å; N117-Y302 VanDerWaalsContact OD1-OH 3.06Å; L118-Y302 HydrophobicContact CD1-CD2 4.43Å; L118-Y302 HydrophobicContact CD2-CD2 3.81Å; L118-Y302 HydrophobicContact CD2-CE2 3.6Å; L118-Y302 HydrophobicContact CG-CD2 4.05Å; L118-Y302 HydrophobicContact CG-CE2 4.09Å; I289-Y302 HydrophobicContact CD1-CE1 3.59Å; I289-Y302 HydrophobicContact CG1-CE1 4.15Å; I289-Y302 HydrophobicContact CG2-CD1 4.4Å; I289-Y302 HydrophobicContact CG2-CE1 4.15Å; D300-Y302 VanDerWaalsContact C-N 3.27Å; D300-Y302 PolarHBondContact O-N 3.47Å; D300-Y302 VanDerWaalsContact OD2-CB 3.32Å; D300-Y302 WeakPolarHBondContact OD2-CB 3.39Å; D300-Y302 PolarHBondContact OD2-N 3.18Å; D300-Y302 VanDerWaalsContact OD2-N 3.16Å; Y302-G304 PolarHBondContact O-N 3Å; Y302-G305 PolarHBondContact O-N 3.36Å; Y302-V306 WeakPolarHBondContact O-CG2 3.5Å; Y302-V306 PolarHBondContact O-N 2.92Å; Y302-L377 HydrophobicContact CE1-CD1 4.11Å
303	Q	85.3	Confident	82.8	Confident	14 Å²	14	34 Å²	34	7%	0.065	19%	0.191	C	C	.	.	H	α-helix	trans	-63	-32.3	179.2	-63.4	-173.5	-63.2	0	0	111.6	I289 F290 S298 D300 V306 I307	I289-Q303 HydrophobicContact CG2-CG 3.99Å; F290-Q303 HydrophobicContact CE1-CB 4.18Å; F290-Q303 HydrophobicContact CZ-CB 4.47Å; S298-Q303 PolarHBondContact O-OE1 2.96Å; S298-Q303 PolarHBondContact OG-OE1 3.02Å; D300-Q303 HydrophobicContact CB-CB 4.44Å; D300-Q303 HydrophobicContact CB-CG 4.45Å; D300-Q303 PolarHBondContact O-N 3.35Å; Q303-V306 PolarHBondContact O-N 3.38Å; Q303-I307 PolarHBondContact O-N 2.91Å
304	G	85	Confident	83.2	Confident	0 Å²	0	34 Å²	34	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-59.5	-55	172.3	0	0	0	0	0	112.9	D300 Y302 V306 I307 L308	D300-G304 WeakPolarHBondContact O-CA 3.48Å; D300-G304 PolarHBondContact O-N 3.35Å; Y302-G304 PolarHBondContact O-N 3Å; G304-V306 PolarHBondContact O-N 2.93Å; G304-I307 WeakPolarHBondContact O-CG2 3.38Å; G304-I307 PolarHBondContact O-N 2.79Å; G304-L308 WeakPolarHBondContact O-CB 3.47Å; G304-L308 VanDerWaalsContact O-CG 3.24Å; G304-L308 WeakPolarHBondContact O-CG 3.3Å; G304-L308 PolarHBondContact O-N 3.49Å
305	G	87.1	Confident	83.8	Confident	0 Å²	0	29.9 Å²	29.9	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-58.3	-35.2	176.9	0	0	0	0	0	113.3	I301 Y302 G309	I301-G305 PolarHBondContact O-N 2.65Å; Y302-G305 PolarHBondContact O-N 3.36Å; G305-G309 PolarHBondContact O-N 3.26Å; G305-G309 VanDerWaalsContact O-N 3.16Å
306	V	89.1	Confident	84.4	Confident	0 Å²	0	26.4 Å²	26.4	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-70.6	-49.8	176.5	175	0	0	0	0	112	L118 Y286 I289 F290 Y302 Q303 G304 L308 G309 C310	L118-V306 HydrophobicContact CD2-CG2 3.98Å; Y286-V306 HydrophobicContact CD1-CG1 4.32Å; Y286-V306 HydrophobicContact CD1-CG2 3.82Å; Y286-V306 HydrophobicContact CE1-CG2 4.4Å; Y286-V306 HydrophobicContact CG-CG1 4.27Å; I289-V306 HydrophobicContact CD1-CG1 4.45Å; I289-V306 HydrophobicContact CD1-CG2 4Å; F290-V306 HydrophobicContact CE2-CG1 3.82Å; F290-V306 HydrophobicContact CZ-CG1 4.23Å; Y302-V306 WeakPolarHBondContact O-CG2 3.5Å; Y302-V306 PolarHBondContact O-N 2.92Å; Q303-V306 PolarHBondContact O-N 3.38Å; G304-V306 PolarHBondContact O-N 2.93Å; V306-L308 VanDerWaalsContact C-N 3.32Å; V306-L308 PolarHBondContact O-N 3.41Å; V306-G309 CarbonylContact O-C 3.6Å; V306-G309 WeakPolarHBondContact O-CA 3.41Å; V306-G309 PolarHBondContact O-N 2.92Å; V306-G309 VanDerWaalsContact O-N 3.1Å; V306-C310 PolarHBondContact O-N 3.21Å; V306-C310 PolarHBondContact O-SG 3.22Å
307	I	88.4	Confident	85.4	Confident	2 Å²	2	24.3 Å²	24.3	1%	0.01	15%	0.148	C	C	.	.	H	α-helix	trans	-65.2	-37.1	-177.4	-162.5	64.3	0	0	0	111.4	A265 F266 A274 F290 Q303 G304 G309 C310 L311	A265-I307 HydrophobicContact CB-CG2 4.17Å; F266-I307 HydrophobicContact CE1-CB 4.43Å; F266-I307 HydrophobicContact CE1-CG2 3.84Å; F266-I307 HydrophobicContact CE2-CG2 3.84Å; F266-I307 HydrophobicContact CZ-CB 4.4Å; F266-I307 HydrophobicContact CZ-CG2 3.46Å; F266-I307 VanDerWaalsContact CZ-CG2 3.46Å; A274-I307 HydrophobicContact CB-CD1 3.9Å; F290-I307 HydrophobicContact CZ-CB 4.16Å; F290-I307 HydrophobicContact CZ-CD1 4.25Å; Q303-I307 PolarHBondContact O-N 2.91Å; G304-I307 WeakPolarHBondContact O-CG2 3.38Å; G304-I307 PolarHBondContact O-N 2.79Å; I307-G309 VanDerWaalsContact C-N 3.33Å; I307-G309 PolarHBondContact O-N 2.81Å; I307-C310 PolarHBondContact O-N 3.5Å; I307-C310 VanDerWaalsContact O-N 3.16Å; I307-L311 HydrophobicContact CG1-CD1 3.96Å; I307-L311 HydrophobicContact CG1-CG 4.35Å; I307-L311 WeakPolarHBondContact O-CB 3.38Å; I307-L311 WeakPolarHBondContact O-CG 3.17Å; I307-L311 PolarHBondContact O-N 2.9Å
308	L	88.8	Confident	86.5	Confident	0 Å²	0	29.1 Å²	29.1	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-61.3	-43	172.3	-65.1	175.4	0	0	0	111.1	V261 F262 A265 G304 V306 C310 L311 F312 A316 W320	V261-L308 HydrophobicContact CG1-CD1 3.73Å; V261-L308 HydrophobicContact CG1-CD2 3.43Å; V261-L308 VanDerWaalsContact CG1-CD2 3.43Å; V261-L308 HydrophobicContact CG1-CG 4.22Å; F262-L308 HydrophobicContact CE1-CD1 4.15Å; A265-L308 HydrophobicContact CB-CD2 3.85Å; G304-L308 WeakPolarHBondContact O-CB 3.47Å; G304-L308 VanDerWaalsContact O-CG 3.24Å; G304-L308 WeakPolarHBondContact O-CG 3.3Å; G304-L308 PolarHBondContact O-N 3.49Å; V306-L308 VanDerWaalsContact C-N 3.32Å; V306-L308 PolarHBondContact O-N 3.41Å; L308-C310 VanDerWaalsContact C-N 3.32Å; L308-C310 PolarHBondContact O-N 3.16Å; L308-L311 PolarHBondContact O-N 2.8Å; L308-F312 HydrophobicContact CB-CD2 4.4Å; L308-F312 HydrophobicContact CD2-CD2 3.8Å; L308-F312 HydrophobicContact CD2-CE2 3.62Å; L308-F312 WeakPolarHBondContact O-CB 3.5Å; L308-F312 PolarHBondContact O-N 3.24Å; L308-A316 HydrophobicContact CB-CB 4.42Å; L308-W320 HydrophobicContact CD1-CD2 4.2Å; L308-W320 HydrophobicContact CD1-CE3 3.79Å; L308-W320 HydrophobicContact CD1-CZ3 4.33Å
309	G	89.4	Confident	87.8	Confident	0 Å²	0	28 Å²	28	0%	0	16%	0.155	C	C	.	.	H	α-helix	trans	-59.2	-37.9	172	0	0	0	0	0	114.4	L283 G305 V306 I307 G313	L283-G309 WeakPolarHBondContact CD1-O 3.47Å; G305-G309 PolarHBondContact O-N 3.26Å; G305-G309 VanDerWaalsContact O-N 3.16Å; V306-G309 CarbonylContact O-C 3.6Å; V306-G309 WeakPolarHBondContact O-CA 3.41Å; V306-G309 PolarHBondContact O-N 2.92Å; V306-G309 VanDerWaalsContact O-N 3.1Å; I307-G309 VanDerWaalsContact C-N 3.33Å; I307-G309 PolarHBondContact O-N 2.81Å; G309-G313 WeakPolarHBondContact CA-O 3.29Å; G309-G313 CarbonylContact O-C 3.1Å; G309-G313 WeakPolarHBondContact O-CA 3.46Å; G309-G313 PolarHBondContact O-N 3.41Å; G309-G313 VanDerWaalsContact O-N 3.08Å
310	C	89.8	Confident	88.8	Confident	12 Å²	12	25.6 Å²	25.6	8%	0.081	14%	0.139	C	C	.	.	H	α-helix	trans	-75.6	-36.9	178.6	-59.7	0	0	0	0	113.1	I277 C278 V306 I307 L308	I277-C310 HydrophobicContact CG2-CB 4.14Å; C278-C310 WeakPolarHBondContact CA-SG 3.39Å; C278-C310 HydrophobicContact CB-CB 3.96Å; C278-C310 WeakPolarHBondContact CB-SG 3.46Å; C278-C310 WeakPolarHBondContact SG-CB 3.32Å; C278-C310 CovalentContact SG-SG 2.04Å; C278-C310 PolarHBondContact SG-SG 3.44Å; V306-C310 PolarHBondContact O-N 3.21Å; V306-C310 PolarHBondContact O-SG 3.22Å; I307-C310 PolarHBondContact O-N 3.5Å; I307-C310 VanDerWaalsContact O-N 3.16Å; L308-C310 VanDerWaalsContact C-N 3.32Å; L308-C310 PolarHBondContact O-N 3.16Å
311	L	88.7	Confident	89.6	Confident	70 Å²	70	24.9 Å²	24.9	37%	0.366	14%	0.135	S	C	.	.	H	α-helix	trans	-80.1	-47.3	-178.7	-73.4	169.7	0	0	0	112.9	A265 I277 I307 L308	A265-L311 HydrophobicContact CB-CD1 4.04Å; I277-L311 HydrophobicContact CD1-CD2 4.25Å; I277-L311 HydrophobicContact CG2-CD2 3.86Å; I277-L311 HydrophobicContact CG2-CG 4.34Å; I307-L311 HydrophobicContact CG1-CD1 3.96Å; I307-L311 HydrophobicContact CG1-CG 4.35Å; I307-L311 WeakPolarHBondContact O-CB 3.38Å; I307-L311 WeakPolarHBondContact O-CG 3.17Å; I307-L311 PolarHBondContact O-N 2.9Å; L308-L311 PolarHBondContact O-N 2.8Å
312	F	88.2	Confident	90.2	Very high	69 Å²	69	25.8 Å²	25.8	30%	0.303	14%	0.143	S	C	.	.	H	α-helix	trans	-109	-3.8	-170.3	-54	-59.5	0	0	0	113.2	V172 A173 L308 A316	V172-F312 HydrophobicContact CG1-CB 3.76Å; V172-F312 HydrophobicContact CG1-CD1 3.85Å; V172-F312 HydrophobicContact CG1-CG 3.87Å; A173-F312 HydrophobicContact CB-CE2 3.98Å; A173-F312 HydrophobicContact CB-CZ 3.8Å; L308-F312 HydrophobicContact CB-CD2 4.4Å; L308-F312 HydrophobicContact CD2-CD2 3.8Å; L308-F312 HydrophobicContact CD2-CE2 3.62Å; L308-F312 WeakPolarHBondContact O-CB 3.5Å; L308-F312 PolarHBondContact O-N 3.24Å; F312-A316 HydrophobicContact CB-CB 3.98Å
313	G	89.5	Confident	90.7	Very high	21 Å²	21	24.8 Å²	24.8	22%	0.216	14%	0.139	C	C	.	.			trans	100	169.8	173.1	0	0	0	0	0	114.2	G309 A315 A316	G309-G313 WeakPolarHBondContact CA-O 3.29Å; G309-G313 CarbonylContact O-C 3.1Å; G309-G313 WeakPolarHBondContact O-CA 3.46Å; G309-G313 PolarHBondContact O-N 3.41Å; G309-G313 VanDerWaalsContact O-N 3.08Å; G313-A315 PolarHBondContact O-N 3.36Å; G313-A316 WeakPolarHBondContact O-CB 3.35Å; G313-A316 PolarHBondContact O-N 3.12Å
314	P	89.6	Confident	91	Very high	60 Å²	60	24.9 Å²	24.9	39%	0.39	14%	0.14	S	C	.	.	H	α-helix	trans	-56.3	-29.3	-170.8	-22.9	29	0	0	0	115.1	L283 A316 L317 Y318	L283-P314 HydrophobicContact CD1-CB 4.21Å; L283-P314 HydrophobicContact CD1-CG 3.71Å; P314-A316 VanDerWaalsContact C-N 3.32Å; P314-A316 PolarHBondContact O-N 2.95Å; P314-L317 PolarHBondContact O-N 3.27Å; P314-Y318 HydrophobicContact CB-CE2 4.44Å; P314-Y318 WeakPolarHBondContact O-CD2 3.29Å; P314-Y318 PolarHBondContact O-N 3.5Å
315	A	91.9	Very high	91.4	Very high	51 Å²	51	26.7 Å²	26.7	42%	0.421	15%	0.15	S	C	.	.	H	α-helix	trans	-60.4	-41	178.6	0	0	0	0	0	112.1	G313 L317 Y318 I319	G313-A315 PolarHBondContact O-N 3.36Å; A315-L317 PolarHBondContact O-N 2.95Å; A315-Y318 PolarHBondContact O-N 3Å; A315-I319 WeakPolarHBondContact O-CB 3.47Å; A315-I319 VanDerWaalsContact O-CG1 3.26Å; A315-I319 WeakPolarHBondContact O-CG1 3.44Å; A315-I319 PolarHBondContact O-N 3.29Å
316	A	91.7	Very high	91.7	Very high	2 Å²	2	27 Å²	27	2%	0.017	15%	0.152	C	C	.	.	H	α-helix	trans	-62.1	-42.3	179.9	0	0	0	0	0	112.1	E169 L308 F312 G313 P314 Y318 I319 W320	E169-A316 VanDerWaalsContact OE1-CA 3.25Å; E169-A316 WeakPolarHBondContact OE1-CA 3.46Å; E169-A316 WeakPolarHBondContact OE2-CB 3.47Å; L308-A316 HydrophobicContact CB-CB 4.42Å; F312-A316 HydrophobicContact CB-CB 3.98Å; G313-A316 WeakPolarHBondContact O-CB 3.35Å; G313-A316 PolarHBondContact O-N 3.12Å; P314-A316 VanDerWaalsContact C-N 3.32Å; P314-A316 PolarHBondContact O-N 2.95Å; A316-Y318 PolarHBondContact O-N 3.39Å; A316-I319 PolarHBondContact O-N 3.34Å; A316-W320 VanDerWaalsContact O-CB 3.24Å; A316-W320 WeakPolarHBondContact O-CB 3.4Å; A316-W320 PolarHBondContact O-N 3.33Å
317	L	92.3	Very high	91.8	Very high	2 Å²	2	28.5 Å²	28.5	1%	0.01	17%	0.165	C	C	.	.	H	α-helix	trans	-59.2	-45.1	175.7	-177.2	155.1	0	0	0	112.1	L118 L283 P314 A315 A321	L118-L317 HydrophobicContact CB-CD2 4Å; L118-L317 HydrophobicContact CD2-CD1 4.23Å; L118-L317 HydrophobicContact CD2-CD2 4.29Å; L118-L317 HydrophobicContact CD2-CG 4.25Å; L283-L317 HydrophobicContact CD2-CB 4.44Å; L283-L317 HydrophobicContact CD2-CD1 3.46Å; L283-L317 VanDerWaalsContact CD2-CD1 3.46Å; P314-L317 PolarHBondContact O-N 3.27Å; A315-L317 PolarHBondContact O-N 2.95Å; L317-A321 WeakPolarHBondContact O-CB 3.12Å; L317-A321 PolarHBondContact O-N 3.03Å
318	Y	94.3	Very high	91.9	Very high	102 Å²	102	28.7 Å²	28.7	40%	0.4	17%	0.166	S	C	.	.	H	α-helix	trans	-71.7	-37.4	179.7	-66.9	-61.8	0	0	0	112.3	L119 P314 A315 A316 A321 V322	L119-Y318 HydrophobicContact CD2-CD1 4.28Å; P314-Y318 HydrophobicContact CB-CE2 4.44Å; P314-Y318 WeakPolarHBondContact O-CD2 3.29Å; P314-Y318 PolarHBondContact O-N 3.5Å; A315-Y318 PolarHBondContact O-N 3Å; A316-Y318 PolarHBondContact O-N 3.39Å; Y318-A321 PolarHBondContact O-N 3.48Å; Y318-V322 WeakPolarHBondContact O-CG2 3.43Å; Y318-V322 PolarHBondContact O-N 3.48Å
319	I	95.1	Very high	92	Very high	44 Å²	44	30.1 Å²	30.1	23%	0.226	17%	0.173	C	C	.	.	H	α-helix	trans	-65.6	-45	176.5	-71.9	168.7	0	0	0	110.5	T165 Y168 E169 A315 A316 A321 V322 G323	T165-I319 WeakPolarHBondContact CB-O 3.32Å; T165-I319 HydrophobicContact CG2-CG2 3.98Å; Y168-I319 HydrophobicContact CD1-CD1 3.48Å; Y168-I319 VanDerWaalsContact CD1-CD1 3.48Å; Y168-I319 HydrophobicContact CD1-CG2 4.04Å; Y168-I319 HydrophobicContact CE1-CD1 3.38Å; Y168-I319 HydrophobicContact CG-CD1 4.14Å; E169-I319 HydrophobicContact CG-CG2 4.49Å; E169-I319 WeakPolarHBondContact OE1-CG2 3.36Å; A315-I319 WeakPolarHBondContact O-CB 3.47Å; A315-I319 VanDerWaalsContact O-CG1 3.26Å; A315-I319 WeakPolarHBondContact O-CG1 3.44Å; A315-I319 PolarHBondContact O-N 3.29Å; A316-I319 PolarHBondContact O-N 3.34Å; I319-A321 VanDerWaalsContact C-N 3.34Å; I319-A321 PolarHBondContact O-N 3.13Å; I319-V322 PolarHBondContact O-N 3.35Å; I319-G323 PolarHBondContact O-N 3.22Å
320	W	94.3	Very high	91.9	Very high	8 Å²	8	30.9 Å²	30.9	3%	0.03	18%	0.179	C	C	.	.	H	α-helix	trans	-54.1	-48.9	170.1	178.4	-97.3	0	0	0	111.9	F166 V258 F262 I301 L308 A316 V322 G323 L324	F166-W320 AromaticContact CD1-CE3 3.92Å; F166-W320 HydrophobicContact CD1-CE3 3.92Å; F166-W320 AromaticContact CD1-CZ3 3.79Å; F166-W320 HydrophobicContact CD1-CZ3 3.79Å; F166-W320 HydrophobicContact CE1-CD2 4.3Å; F166-W320 AromaticContact CE1-CE3 3.68Å; F166-W320 HydrophobicContact CE1-CE3 3.68Å; F166-W320 HydrophobicContact CE1-CH2 4.17Å; F166-W320 AromaticContact CE1-CZ3 3.61Å; F166-W320 HydrophobicContact CE1-CZ3 3.61Å; V258-W320 HydrophobicContact CG1-CH2 3.96Å; V258-W320 HydrophobicContact CG1-CZ3 4.36Å; V258-W320 HydrophobicContact CG2-CZ3 4.35Å; F262-W320 HydrophobicContact CD1-CH2 4.38Å; F262-W320 HydrophobicContact CE1-CE3 4.47Å; F262-W320 AromaticContact CE1-CH2 3.43Å; F262-W320 HydrophobicContact CE1-CH2 3.43Å; F262-W320 VanDerWaalsContact CE1-CH2 3.43Å; F262-W320 AromaticContact CE1-CZ2 3.77Å; F262-W320 HydrophobicContact CE1-CZ2 3.77Å; F262-W320 AromaticContact CE1-CZ3 3.81Å; F262-W320 HydrophobicContact CE1-CZ3 3.81Å; F262-W320 HydrophobicContact CE2-CH2 4.07Å; F262-W320 HydrophobicContact CE2-CZ2 4.27Å; F262-W320 AromaticContact CZ-CH2 3.25Å; F262-W320 HydrophobicContact CZ-CH2 3.25Å; F262-W320 AromaticContact CZ-CZ2 3.31Å; F262-W320 HydrophobicContact CZ-CZ2 3.31Å; F262-W320 HydrophobicContact CZ-CZ3 4.12Å; I301-W320 HydrophobicContact CG2-CZ2 4.16Å; I301-W320 PolarHBondContact O-NE1 3.19Å; I301-W320 VanDerWaalsContact O-NE1 3.14Å; L308-W320 HydrophobicContact CD1-CD2 4.2Å; L308-W320 HydrophobicContact CD1-CE3 3.79Å; L308-W320 HydrophobicContact CD1-CZ3 4.33Å; A316-W320 VanDerWaalsContact O-CB 3.24Å; A316-W320 WeakPolarHBondContact O-CB 3.4Å; A316-W320 PolarHBondContact O-N 3.33Å; W320-V322 PolarHBondContact O-N 3.01Å; W320-G323 PolarHBondContact O-N 3.13Å; W320-L324 WeakPolarHBondContact O-CB 3.45Å; W320-L324 PolarHBondContact O-N 3.26Å
321	A	94.6	Very high	91.7	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-66.6	-36.5	-178.7	0	0	0	0	0	113	S115 L118 L119 L317 Y318 I319 L324 L325	S115-A321 WeakPolarHBondContact CB-O 3.25Å; L118-A321 HydrophobicContact CB-CB 3.68Å; L118-A321 HydrophobicContact CD1-CB 4.26Å; L119-A321 HydrophobicContact CD2-CB 3.86Å; L119-A321 HydrophobicContact CG-CB 3.79Å; L317-A321 WeakPolarHBondContact O-CB 3.12Å; L317-A321 PolarHBondContact O-N 3.03Å; Y318-A321 PolarHBondContact O-N 3.48Å; I319-A321 VanDerWaalsContact C-N 3.34Å; I319-A321 PolarHBondContact O-N 3.13Å; A321-L324 PolarHBondContact O-N 3.17Å; A321-L325 WeakPolarHBondContact O-CB 3.31Å; A321-L325 PolarHBondContact O-N 3.46Å
322	V	95.9	Very high	91.5	Very high	63 Å²	63	28.2 Å²	28.2	38%	0.382	17%	0.166	S	C	.	.	H	α-helix	trans	-64.7	-42.2	171.8	171.2	0	0	0	0	111.4	L119 I161 T165 Y318 I319 W320 L325 A326	L119-V322 HydrophobicContact CD2-CG2 3.99Å; I161-V322 HydrophobicContact CG2-CG1 3.88Å; T165-V322 HydrophobicContact CG2-CB 4.4Å; T165-V322 HydrophobicContact CG2-CG1 4.16Å; Y318-V322 WeakPolarHBondContact O-CG2 3.43Å; Y318-V322 PolarHBondContact O-N 3.48Å; I319-V322 PolarHBondContact O-N 3.35Å; W320-V322 PolarHBondContact O-N 3.01Å; V322-L325 PolarHBondContact O-N 3.35Å; V322-A326 PolarHBondContact O-N 3.23Å
323	G	94.8	Very high	91.2	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-62	-43.7	175.8	0	0	0	0	0	112.5	T165 I319 W320 A326 A327	T165-G323 WeakPolarHBondContact OG1-CA 3.05Å; I319-G323 PolarHBondContact O-N 3.22Å; W320-G323 PolarHBondContact O-N 3.13Å; G323-A326 PolarHBondContact O-N 2.97Å; G323-A327 PolarHBondContact O-N 3.22Å
324	L	92.5	Very high	91.1	Very high	16 Å²	16	25.5 Å²	25.5	8%	0.084	15%	0.151	C	C	.	.	H	α-helix	trans	-65.4	-40.2	176.7	-176.3	64	0	0	0	112.5	G111 I114 I301 W320 A321 A327 G328	G111-L324 VanDerWaalsContact O-CD2 3.32Å; G111-L324 WeakPolarHBondContact O-CD2 3.45Å; G111-L324 WeakPolarHBondContact O-CG 3.48Å; I114-L324 HydrophobicContact CB-CD2 4.03Å; I114-L324 HydrophobicContact CG2-CD2 3.54Å; I301-L324 HydrophobicContact CG2-CD1 3.62Å; I301-L324 HydrophobicContact CG2-CD2 3.47Å; I301-L324 VanDerWaalsContact CG2-CD2 3.47Å; I301-L324 HydrophobicContact CG2-CG 4.19Å; W320-L324 WeakPolarHBondContact O-CB 3.45Å; W320-L324 PolarHBondContact O-N 3.26Å; A321-L324 PolarHBondContact O-N 3.17Å; L324-A327 PolarHBondContact O-N 3.42Å; L324-G328 PolarHBondContact O-N 3.1Å
325	L	93.6	Very high	90.9	Very high	39 Å²	39	22.8 Å²	22.8	20%	0.204	13%	0.134	C	C	.	.	H	α-helix	trans	-60.5	-48.3	173	179.7	58.2	0	0	0	110.5	T112 S115 F116 L119 A321 V322 A327 G328 Q329	T112-L325 HydrophobicContact CG2-CD1 3.89Å; S115-L325 WeakPolarHBondContact OG-CB 3.42Å; F116-L325 HydrophobicContact CE2-CD1 4.3Å; F116-L325 HydrophobicContact CZ-CD1 4.15Å; L119-L325 HydrophobicContact CD1-CD2 4.04Å; A321-L325 WeakPolarHBondContact O-CB 3.31Å; A321-L325 PolarHBondContact O-N 3.46Å; V322-L325 PolarHBondContact O-N 3.35Å; L325-A327 VanDerWaalsContact C-N 3.3Å; L325-A327 PolarHBondContact O-N 2.86Å; L325-G328 PolarHBondContact O-N 3.26Å; L325-Q329 HydrophobicContact CD1-CG 4.24Å; L325-Q329 HydrophobicContact CG-CG 4.49Å; L325-Q329 WeakPolarHBondContact O-CG 3.36Å; L325-Q329 PolarHBondContact O-N 3.13Å
326	A	93.5	Very high	90.5	Very high	6 Å²	6	20.7 Å²	20.7	5%	0.05	12%	0.116	C	C	.	.	H	α-helix	trans	-61.4	-36.5	178.2	0	0	0	0	0	113	L158 I161 M162 V322 G323 S330	L158-A326 HydrophobicContact CD2-CB 4.14Å; I161-A326 HydrophobicContact CB-CB 4.14Å; I161-A326 HydrophobicContact CG2-CB 3.76Å; M162-A326 HydrophobicContact CG-CB 4Å; V322-A326 PolarHBondContact O-N 3.23Å; G323-A326 PolarHBondContact O-N 2.97Å; A326-S330 WeakPolarHBondContact O-CB 3.39Å; A326-S330 PolarHBondContact O-N 2.87Å
327	A	91.6	Very high	90.2	Very high	32 Å²	32	21.5 Å²	21.5	26%	0.264	12%	0.118	S	C	.	.	H	α-helix	trans	-63.5	-45.8	173.5	0	0	0	0	0	112.2	M162 G323 L324 L325 S330 S331	M162-A327 HydrophobicContact CG-CB 4.41Å; M162-A327 WeakPolarHBondContact SD-CA 3.35Å; M162-A327 HydrophobicContact SD-CB 3.53Å; M162-A327 VanDerWaalsContact SD-CB 3.53Å; G323-A327 PolarHBondContact O-N 3.22Å; L324-A327 PolarHBondContact O-N 3.42Å; L325-A327 VanDerWaalsContact C-N 3.3Å; L325-A327 PolarHBondContact O-N 2.86Å; A327-S330 PolarHBondContact O-N 3.33Å; A327-S331 PolarHBondContact O-N 2.9Å
328	G	90.3	Very high	90.1	Very high	5 Å²	5	21.4 Å²	21.4	5%	0.052	12%	0.118	C	C	.	.	H	α-helix	trans	-58.1	-55.2	174.6	0	0	0	0	0	111.9	E108 L324 L325 S330 S331 T332	E108-G328 WeakPolarHBondContact CG-O 3.36Å; L324-G328 PolarHBondContact O-N 3.1Å; L325-G328 PolarHBondContact O-N 3.26Å; G328-S330 PolarHBondContact O-N 3.23Å; G328-S330 VanDerWaalsContact O-N 3.11Å; G328-S331 PolarHBondContact O-N 3.49Å; G328-T332 PolarHBondContact O-N 2.94Å; G328-T332 PolarHBondContact O-OG1 3.06Å
329	Q	89.6	Confident	89.7	Confident	30 Å²	30	16.6 Å²	16.6	14%	0.14	10%	0.099	C	C	.	.	H	α-helix	trans	-56.5	-31.8	178	-59.6	-57.5	-98.2	0	0	113.1	D136 L158 L325 T332 M333	D136-Q329 VanDerWaalsContact CG-OE1 3.3Å; D136-Q329 PolarHBondContact OD1-OE1 3.34Å; D136-Q329 PolarHBondContact OD2-NE2 2.99Å; L158-Q329 HydrophobicContact CD1-CB 3.85Å; L158-Q329 HydrophobicContact CD2-CB 4.26Å; L325-Q329 HydrophobicContact CD1-CG 4.24Å; L325-Q329 HydrophobicContact CG-CG 4.49Å; L325-Q329 WeakPolarHBondContact O-CG 3.36Å; L325-Q329 PolarHBondContact O-N 3.13Å; Q329-T332 PolarHBondContact O-OG1 3.27Å; Q329-T332 VanDerWaalsContact O-OG1 3.14Å; Q329-M333 VanDerWaalsContact O-CG 3.29Å; Q329-M333 WeakPolarHBondContact O-CG 3.35Å
330	S	88.9	Confident	89.3	Confident	17 Å²	17	16.4 Å²	16.4	12%	0.119	10%	0.098	C	C	.	.	H	α-helix	trans	-74.7	-27.4	177.8	-169.2	0	0	0	0	113.1	F155 A326 A327 G328	F155-S330 WeakPolarHBondContact CE1-O 3.32Å; A326-S330 WeakPolarHBondContact O-CB 3.39Å; A326-S330 PolarHBondContact O-N 2.87Å; A327-S330 PolarHBondContact O-N 3.33Å; G328-S330 PolarHBondContact O-N 3.23Å; G328-S330 VanDerWaalsContact O-N 3.11Å
331	S	85.9	Confident	89	Confident	25 Å²	25	18.2 Å²	18.2	18%	0.175	11%	0.106	C	C	.	.	H	α-helix	trans	-87	-26	-176.4	173	0	0	0	0	113	A327 G328 M333 T334 G335	A327-S331 PolarHBondContact O-N 2.9Å; G328-S331 PolarHBondContact O-N 3.49Å; S331-M333 VanDerWaalsContact C-N 3.33Å; S331-M333 PolarHBondContact O-N 2.83Å; S331-T334 WeakPolarHBondContact CA-OG1 3.42Å; S331-T334 PolarHBondContact O-N 3.21Å; S331-T334 PolarHBondContact O-OG1 3.49Å; S331-G335 PolarHBondContact O-N 2.92Å
332	T	83.9	Confident	88.8	Confident	1 Å²	1	18.2 Å²	18.2	1%	0.006	11%	0.106	C	C	.	.	H	α-helix	trans	-62.3	-43.4	174.2	28.9	0	0	0	0	111.6	E108 F140 G328 Q329 T336	E108-T332 VanDerWaalsContact CD-CB 3.44Å; E108-T332 WeakPolarHBondContact OE1-CB 3.24Å; E108-T332 WeakPolarHBondContact OE2-CA 3.45Å; E108-T332 VanDerWaalsContact OE2-CB 3.26Å; E108-T332 WeakPolarHBondContact OE2-CB 3.46Å; E108-T332 PolarHBondContact OE2-N 2.99Å; F140-T332 HydrophobicContact CB-CG2 4.43Å; F140-T332 HydrophobicContact CG-CG2 4.48Å; G328-T332 PolarHBondContact O-N 2.94Å; G328-T332 PolarHBondContact O-OG1 3.06Å; Q329-T332 PolarHBondContact O-OG1 3.27Å; Q329-T332 VanDerWaalsContact O-OG1 3.14Å; T332-T336 WeakPolarHBondContact O-CB 3.45Å; T332-T336 VanDerWaalsContact O-CG2 3.28Å; T332-T336 WeakPolarHBondContact O-CG2 3.24Å; T332-T336 PolarHBondContact O-N 3.22Å; T332-T336 PolarHBondContact O-OG1 3.1Å
333	M	82.1	Confident	88.5	Confident	4 Å²	4	15.8 Å²	15.8	2%	0.02	9%	0.09	C	C	.	.	H	α-helix	trans	-68.3	-39.9	-178.9	-50.1	176.8	80.8	0	0	111.7	F140 L151 F154 F155 L158 Q329 S331 T336 Y337	F140-M333 HydrophobicContact CD2-CB 4.03Å; F140-M333 HydrophobicContact CD2-CE 3.75Å; F140-M333 HydrophobicContact CD2-CG 3.52Å; F140-M333 HydrophobicContact CD2-SD 4.43Å; F140-M333 HydrophobicContact CE2-CB 3.71Å; F140-M333 HydrophobicContact CE2-CE 3.86Å; F140-M333 HydrophobicContact CE2-CG 3.74Å; F140-M333 HydrophobicContact CG-CG 4.37Å; F140-M333 HydrophobicContact CZ-CB 4.44Å; L151-M333 HydrophobicContact CD1-CE 3.88Å; L151-M333 HydrophobicContact CD2-CE 3.66Å; L151-M333 HydrophobicContact CG-CE 3.49Å; L151-M333 VanDerWaalsContact CG-CE 3.49Å; F154-M333 HydrophobicContact CD1-CE 3.64Å; F154-M333 HydrophobicContact CD1-SD 3.63Å; F154-M333 HydrophobicContact CE1-CE 4.08Å; F154-M333 HydrophobicContact CE1-SD 3.7Å; F155-M333 HydrophobicContact CD1-SD 4.14Å; F155-M333 HydrophobicContact CE1-CB 3.51Å; F155-M333 HydrophobicContact CE1-CG 4.15Å; F155-M333 HydrophobicContact CE1-SD 3.72Å; F155-M333 HydrophobicContact CZ-CB 3.4Å; F155-M333 VanDerWaalsContact CZ-CB 3.4Å; F155-M333 HydrophobicContact CZ-CG 4.38Å; F155-M333 HydrophobicContact CZ-SD 4.19Å; L158-M333 HydrophobicContact CD1-SD 4.41Å; Q329-M333 VanDerWaalsContact O-CG 3.29Å; Q329-M333 WeakPolarHBondContact O-CG 3.35Å; S331-M333 VanDerWaalsContact C-N 3.33Å; S331-M333 PolarHBondContact O-N 2.83Å; M333-T336 PolarHBondContact O-OG1 2.93Å; M333-T336 VanDerWaalsContact O-OG1 3.05Å; M333-Y337 WeakPolarHBondContact O-CD2 3.43Å; M333-Y337 PolarHBondContact O-N 3.33Å
334	T	86.4	Confident	88.2	Confident	29 Å²	29	18.4 Å²	18.4	18%	0.178	10%	0.103	C	C	.	.	H	α-helix	trans	-71	-42.7	176.6	53.5	0	0	0	0	111.8	F155 L215 S331 T336 Y337 A338	F155-T334 HydrophobicContact CE1-CG2 4.07Å; F155-T334 HydrophobicContact CZ-CG2 3.93Å; L215-T334 HydrophobicContact CD2-CG2 4.06Å; S331-T334 WeakPolarHBondContact CA-OG1 3.42Å; S331-T334 PolarHBondContact O-N 3.21Å; S331-T334 PolarHBondContact O-OG1 3.49Å; T334-T336 PolarHBondContact O-N 3.48Å; T334-Y337 PolarHBondContact O-N 3.44Å; T334-A338 VanDerWaalsContact O-CB 3.29Å; T334-A338 WeakPolarHBondContact O-CB 3.41Å; T334-A338 PolarHBondContact O-N 3.36Å
335	G	86.1	Confident	88	Confident	3 Å²	3	17.7 Å²	17.7	3%	0.031	10%	0.099	C	C	.	.	H	α-helix	trans	-60.6	-43.5	177.6	0	0	0	0	0	113	I101 S331 A338 G339	I101-G335 WeakPolarHBondContact CG2-O 3.41Å; S331-G335 PolarHBondContact O-N 2.92Å; G335-A338 PolarHBondContact O-N 2.91Å; G335-G339 PolarHBondContact O-N 3.41Å
336	T	83.9	Confident	87.7	Confident	7 Å²	7	15.8 Å²	15.8	4%	0.043	9%	0.089	C	C	.	.	H	α-helix	trans	-67.6	-41	178.4	49.4	0	0	0	0	113.1	F140 T332 M333 T334 Q340 V357	F140-T336 HydrophobicContact CD1-CG2 4.4Å; F140-T336 HydrophobicContact CE1-CG2 4.07Å; F140-T336 WeakPolarHBondContact CE1-OG1 3.03Å; F140-T336 VanDerWaalsContact CZ-OG1 3.22Å; F140-T336 WeakPolarHBondContact CZ-OG1 3.49Å; T332-T336 WeakPolarHBondContact O-CB 3.45Å; T332-T336 VanDerWaalsContact O-CG2 3.28Å; T332-T336 WeakPolarHBondContact O-CG2 3.24Å; T332-T336 PolarHBondContact O-N 3.22Å; T332-T336 PolarHBondContact O-OG1 3.1Å; M333-T336 PolarHBondContact O-OG1 2.93Å; M333-T336 VanDerWaalsContact O-OG1 3.05Å; T334-T336 PolarHBondContact O-N 3.48Å; T336-Q340 PolarHBondContact O-N 3.07Å; T336-V357 HydrophobicContact CG2-CB 4.35Å; T336-V357 HydrophobicContact CG2-CG1 3.87Å; T336-V357 HydrophobicContact CG2-CG2 3.8Å
337	Y	84.9	Confident	87.3	Confident	19 Å²	19	17.6 Å²	17.6	8%	0.075	10%	0.097	C	C	.	.	H	α-helix	trans	-66.8	-40.1	171.6	-78	-54.9	0	0	0	112.6	F140 D144 L151 M333 T334 G339 Q340 F341	F140-Y337 HydrophobicContact CE2-CE2 4.25Å; F140-Y337 HydrophobicContact CZ-CE2 4.12Å; D144-Y337 PolarHBondContact OD1-OH 3.05Å; L151-Y337 HydrophobicContact CD1-CE2 4.03Å; L151-Y337 WeakPolarHBondContact CD1-OH 3.34Å; L151-Y337 HydrophobicContact CD2-CE2 3.75Å; M333-Y337 WeakPolarHBondContact O-CD2 3.43Å; M333-Y337 PolarHBondContact O-N 3.33Å; T334-Y337 PolarHBondContact O-N 3.44Å; Y337-G339 PolarHBondContact O-N 3.43Å; Y337-Q340 WeakPolarHBondContact O-CB 3.38Å; Y337-Q340 PolarHBondContact O-N 3.46Å; Y337-Q340 VanDerWaalsContact O-N 3.15Å; Y337-F341 WeakPolarHBondContact O-CD2 3.28Å; Y337-F341 PolarHBondContact O-N 2.92Å
338	A	89.1	Confident	87	Confident	0 Å²	0	22 Å²	22	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-60.5	-46.6	176.9	0	0	0	0	0	110.8	I101 H211 L215 T334 G335 Q340 F341 V342	I101-A338 HydrophobicContact CD1-CB 4.44Å; I101-A338 HydrophobicContact CG1-CB 4.39Å; H211-A338 HydrophobicContact CB-CB 3.97Å; L215-A338 HydrophobicContact CB-CB 4.16Å; T334-A338 VanDerWaalsContact O-CB 3.29Å; T334-A338 WeakPolarHBondContact O-CB 3.41Å; T334-A338 PolarHBondContact O-N 3.36Å; G335-A338 PolarHBondContact O-N 2.91Å; A338-Q340 VanDerWaalsContact C-N 3.31Å; A338-Q340 PolarHBondContact O-N 3.44Å; A338-F341 PolarHBondContact O-N 2.93Å; A338-V342 VanDerWaalsContact O-CB 3.3Å; A338-V342 WeakPolarHBondContact O-CB 3.43Å; A338-V342 WeakPolarHBondContact O-CG2 3.32Å; A338-V342 PolarHBondContact O-N 2.95Å
339	G	87.7	Confident	86.5	Confident	1 Å²	1	25.6 Å²	25.6	1%	0.01	13%	0.128	C	C	.	.	H	α-helix	trans	-60.3	-36	173.1	0	0	0	0	0	113.6	G335 Y337 M343	G335-G339 PolarHBondContact O-N 3.41Å; Y337-G339 PolarHBondContact O-N 3.43Å; G339-M343 WeakPolarHBondContact O-CB 3.26Å; G339-M343 VanDerWaalsContact O-CG 3.28Å; G339-M343 WeakPolarHBondContact O-CG 3.32Å; G339-M343 PolarHBondContact O-N 2.93Å
340	Q	86.4	Confident	85.7	Confident	40 Å²	40	35.2 Å²	35.2	19%	0.187	16%	0.163	C	C	.	.	H	α-helix	trans	-58.2	-57.1	171.7	163.5	154.1	9.7	0	0	112.1	T336 Y337 A338 V342 M343 E344 R356	T336-Q340 PolarHBondContact O-N 3.07Å; Y337-Q340 WeakPolarHBondContact O-CB 3.38Å; Y337-Q340 PolarHBondContact O-N 3.46Å; Y337-Q340 VanDerWaalsContact O-N 3.15Å; A338-Q340 VanDerWaalsContact C-N 3.31Å; A338-Q340 PolarHBondContact O-N 3.44Å; Q340-V342 VanDerWaalsContact C-N 3.32Å; Q340-V342 PolarHBondContact O-N 3.21Å; Q340-M343 PolarHBondContact O-N 3.41Å; Q340-E344 PolarHBondContact NE2-OE1 2.72Å; Q340-E344 PolarHBondContact NE2-OE2 3.05Å; Q340-E344 VanDerWaalsContact NE2-OE2 3.15Å; Q340-E344 WeakPolarHBondContact O-CB 3.27Å; Q340-E344 PolarHBondContact O-N 2.89Å; Q340-R356 VanDerWaalsContact CG-NH1 3.3Å
341	F	88	Confident	85.1	Confident	45 Å²	45	40.1 Å²	40.1	20%	0.197	18%	0.179	C	C	.	.	H	α-helix	trans	-68.1	-33.1	-175.7	-64.9	-62.3	0	0	0	112.4	L215 A218 Y337 A338 G345	L215-F341 HydrophobicContact CD1-CD2 3.94Å; L215-F341 HydrophobicContact CD1-CE2 4.04Å; A218-F341 HydrophobicContact CB-CB 3.8Å; A218-F341 HydrophobicContact CB-CD1 3.52Å; A218-F341 HydrophobicContact CB-CD2 3.46Å; A218-F341 VanDerWaalsContact CB-CD2 3.46Å; A218-F341 HydrophobicContact CB-CE1 3.88Å; A218-F341 HydrophobicContact CB-CE2 3.83Å; A218-F341 HydrophobicContact CB-CG 3.29Å; A218-F341 HydrophobicContact CB-CZ 4.03Å; Y337-F341 WeakPolarHBondContact O-CD2 3.28Å; Y337-F341 PolarHBondContact O-N 2.92Å; A338-F341 PolarHBondContact O-N 2.93Å; F341-G345 WeakPolarHBondContact O-CA 3.22Å; F341-G345 PolarHBondContact O-N 2.89Å
342	V	90.6	Very high	84.7	Confident	0 Å²	0	42.4 Å²	42.4	0%	0	20%	0.195	C	C	.	.	H	α-helix	trans	-66.4	-50.1	175.4	168.5	0	0	0	0	111.1	I97 I101 Y214 A338 Q340 E344 F346	I97-V342 HydrophobicContact CB-CG1 4.23Å; I97-V342 HydrophobicContact CG2-CB 4.41Å; I97-V342 HydrophobicContact CG2-CG1 3.9Å; I97-V342 HydrophobicContact CG2-CG2 3.63Å; I101-V342 HydrophobicContact CD1-CB 4.27Å; I101-V342 HydrophobicContact CD1-CG1 4.43Å; I101-V342 HydrophobicContact CD1-CG2 4.23Å; Y214-V342 HydrophobicContact CD1-CG2 4.28Å; Y214-V342 HydrophobicContact CG-CG2 3.98Å; A338-V342 VanDerWaalsContact O-CB 3.3Å; A338-V342 WeakPolarHBondContact O-CB 3.43Å; A338-V342 WeakPolarHBondContact O-CG2 3.32Å; A338-V342 PolarHBondContact O-N 2.95Å; Q340-V342 VanDerWaalsContact C-N 3.32Å; Q340-V342 PolarHBondContact O-N 3.21Å; V342-E344 PolarHBondContact O-N 3.48Å; V342-F346 HydrophobicContact CG1-CD2 3.96Å; V342-F346 HydrophobicContact CG1-CE2 4.34Å; V342-F346 WeakPolarHBondContact O-CB 3.47Å; V342-F346 WeakPolarHBondContact O-CD2 3.49Å; V342-F346 PolarHBondContact O-N 3.23Å
343	M	88.3	Confident	84.3	Confident	13 Å²	13	47.7 Å²	47.7	6%	0.064	22%	0.215	C	C	.	.	H	α-helix	trans	-62.4	-44.4	176.8	-70	-172.4	88	0	0	112.8	E98 G339 Q340 L347 K348 W351 R356	E98-M343 WeakPolarHBondContact OE1-CG 3.5Å; G339-M343 WeakPolarHBondContact O-CB 3.26Å; G339-M343 VanDerWaalsContact O-CG 3.28Å; G339-M343 WeakPolarHBondContact O-CG 3.32Å; G339-M343 PolarHBondContact O-N 2.93Å; Q340-M343 PolarHBondContact O-N 3.41Å; M343-L347 WeakPolarHBondContact O-CB 3.45Å; M343-L347 PolarHBondContact O-N 3.27Å; M343-L347 VanDerWaalsContact O-N 3.1Å; M343-K348 PolarHBondContact O-N 2.88Å; M343-W351 HydrophobicContact CE-CE3 4.3Å; M343-R356 HydrophobicContact SD-CG 3.73Å; M343-R356 PolarHBondContact SD-NE 3.16Å
344	E	89.1	Confident	84.1	Confident	55 Å²	55	52 Å²	52	26%	0.257	23%	0.234	S	C	.	.	H	α-helix	trans	-70.1	-41.7	-178.5	-81.8	159.1	-144.5	0	0	112	Q340 V342 K348 R356	Q340-E344 PolarHBondContact NE2-OE1 2.72Å; Q340-E344 PolarHBondContact NE2-OE2 3.05Å; Q340-E344 VanDerWaalsContact NE2-OE2 3.15Å; Q340-E344 WeakPolarHBondContact O-CB 3.27Å; Q340-E344 PolarHBondContact O-N 2.89Å; V342-E344 PolarHBondContact O-N 3.48Å; E344-K348 WeakPolarHBondContact O-CA 3.5Å; E344-K348 PolarHBondContact O-N 3Å; E344-K348 VanDerWaalsContact O-N 3.08Å; E344-R356 IonicContact OE1-CZ 3.64Å; E344-R356 IonicContact OE1-NH1 2.76Å; E344-R356 PolarHBondContact OE1-NH1 3.36Å; E344-R356 IonicContact OE1-NH2 2.7Å; E344-R356 PolarHBondContact OE1-NH2 3.15Å
345	G	87.3	Confident	83.9	Confident	0 Å²	0	52.6 Å²	52.6	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-68.9	-52.5	177.7	0	0	0	0	0	113	G78 H82 F341	G78-G345 CarbonylContact O-C 3.53Å; H82-G345 VanDerWaalsContact CB-O 3.22Å; H82-G345 WeakPolarHBondContact CB-O 2.98Å; F341-G345 WeakPolarHBondContact O-CA 3.22Å; F341-G345 PolarHBondContact O-N 2.89Å
346	F	88.5	Confident	83.6	Confident	0 Å²	0	52.7 Å²	52.7	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-74.3	-43.2	-174.8	-82	-87.1	0	0	0	114	C81 H82 R90 L93 W94 Y214 V342	C81-F346 HydrophobicContact CB-CD1 4.25Å; C81-F346 HydrophobicContact CB-CE1 3.48Å; C81-F346 VanDerWaalsContact CB-CE1 3.48Å; C81-F346 HydrophobicContact CB-CZ 3.72Å; H82-F346 PolarHBondContact ND1-O 3.36Å; R90-F346 HydrophobicContact CG-CD1 3.89Å; L93-F346 HydrophobicContact CB-CE1 4.08Å; L93-F346 HydrophobicContact CD2-CE1 3.7Å; L93-F346 HydrophobicContact CD2-CZ 3.86Å; L93-F346 HydrophobicContact CG-CE1 3.58Å; L93-F346 HydrophobicContact CG-CZ 3.67Å; W94-F346 HydrophobicContact CB-CB 3.86Å; W94-F346 HydrophobicContact CB-CD1 4Å; W94-F346 HydrophobicContact CB-CG 3.91Å; W94-F346 HydrophobicContact CG-CB 4.04Å; W94-F346 HydrophobicContact CG-CG 4.44Å; Y214-F346 AromaticContact CD1-CE2 3.99Å; Y214-F346 HydrophobicContact CD1-CE2 3.99Å; Y214-F346 AromaticContact CE1-CE2 3.41Å; Y214-F346 HydrophobicContact CE1-CE2 3.41Å; Y214-F346 VanDerWaalsContact CE1-CE2 3.41Å; Y214-F346 AromaticContact CE1-CZ 3.64Å; Y214-F346 HydrophobicContact CE1-CZ 3.64Å; Y214-F346 AromaticContact CZ-CZ 3.95Å; V342-F346 HydrophobicContact CG1-CD2 3.96Å; V342-F346 HydrophobicContact CG1-CE2 4.34Å; V342-F346 WeakPolarHBondContact O-CB 3.47Å; V342-F346 WeakPolarHBondContact O-CD2 3.49Å; V342-F346 PolarHBondContact O-N 3.23Å
347	L	85.2	Confident	83.4	Confident	43 Å²	43	52.8 Å²	52.8	23%	0.225	24%	0.242	C	C	.	.	H	α-helix	trans	-107.9	-11.4	-171.6	-59.5	-175	0	0	0	113.7	W94 M343 L349	W94-L347 HydrophobicContact CD2-CD1 3.6Å; W94-L347 HydrophobicContact CD2-CD2 4.28Å; W94-L347 HydrophobicContact CD2-CG 3.98Å; W94-L347 VanDerWaalsContact CE2-CD1 3.44Å; W94-L347 HydrophobicContact CE3-CD1 3.89Å; W94-L347 HydrophobicContact CE3-CD2 4.44Å; W94-L347 HydrophobicContact CE3-CG 4.49Å; W94-L347 HydrophobicContact CG-CD1 4.22Å; W94-L347 HydrophobicContact CG-CD2 4.35Å; W94-L347 HydrophobicContact CG-CG 4.09Å; W94-L347 HydrophobicContact CH2-CD1 3.93Å; W94-L347 HydrophobicContact CZ2-CD1 3.63Å; W94-L347 HydrophobicContact CZ3-CD1 4.04Å; M343-L347 WeakPolarHBondContact O-CB 3.45Å; M343-L347 PolarHBondContact O-N 3.27Å; M343-L347 VanDerWaalsContact O-N 3.1Å; L347-L349 HydrophobicContact CB-CB 4.26Å; L347-L349 HydrophobicContact CB-CD1 3.86Å; L347-L349 HydrophobicContact CB-CG 3.81Å; L347-L349 HydrophobicContact CD1-CD1 3.72Å; L347-L349 HydrophobicContact CG-CD1 4.47Å; L347-L349 PolarHBondContact O-N 3.26Å
348	K	84.3	Confident	83.3	Confident	125 Å²	125	55 Å²	55	54%	0.543	26%	0.255	S	S	.	.			trans	55.9	23.2	-170.7	-64.6	-179.9	173.5	170.1	0	113.2	H82 M343 E344 R350	H82-K348 VanDerWaalsContact NE2-CE 3.26Å; H82-K348 WeakPolarHBondContact NE2-CE 3.25Å; H82-K348 PolarHBondContact NE2-NZ 3.41Å; M343-K348 PolarHBondContact O-N 2.88Å; E344-K348 WeakPolarHBondContact O-CA 3.5Å; E344-K348 PolarHBondContact O-N 3Å; E344-K348 VanDerWaalsContact O-N 3.08Å; K348-R350 PolarHBondContact O-N 3.47Å
349	L	79.6	Confident	83.1	Confident	80 Å²	80	59 Å²	59	42%	0.419	28%	0.275	S	S	.	.			trans	-84.6	105.6	178.9	-73	175.8	0	0	0	110.7	L347 W351 R356	L347-L349 HydrophobicContact CB-CB 4.26Å; L347-L349 HydrophobicContact CB-CD1 3.86Å; L347-L349 HydrophobicContact CB-CG 3.81Å; L347-L349 HydrophobicContact CD1-CD1 3.72Å; L347-L349 HydrophobicContact CG-CD1 4.47Å; L347-L349 PolarHBondContact O-N 3.26Å; L349-W351 PolarHBondContact O-N 3.45Å; L349-R356 PolarHBondContact O-NH2 3.05Å
350	R	73.9	Confident	82.7	Confident	233 Å²	233	59.4 Å²	59.4	88%	0.879	28%	0.278	S	S	*	.			trans	-83.6	89	172.1	-66.2	-176.3	177.9	-178.6	-0.7	110	K348	K348-R350 PolarHBondContact O-N 3.47Å
351	W	75.1	Confident	82.6	Confident	119 Å²	119	57.8 Å²	57.8	45%	0.451	27%	0.27	S	S	.	.			trans	-87.5	160.1	170.7	-99.2	20.5	0	0	0	111.7	M343 L349 A355 R356 L359	M343-W351 HydrophobicContact CE-CE3 4.3Å; L349-W351 PolarHBondContact O-N 3.45Å; W351-A355 HydrophobicContact CE3-CB 4.32Å; W351-R356 HydrophobicContact CE3-CB 4.28Å; W351-L359 HydrophobicContact CH2-CD2 3.82Å; W351-L359 HydrophobicContact CZ3-CB 4.14Å; W351-L359 HydrophobicContact CZ3-CD2 3.62Å; W351-L359 HydrophobicContact CZ3-CG 4.46Å
352	S	78.8	Confident	82.6	Confident	73 Å²	73	59 Å²	59	51%	0.51	28%	0.284	S	S	.	.			trans	-67.7	140.2	168.6	74.1	0	0	0	0	109.6	F354 A355 R356	S352-F354 VanDerWaalsContact C-N 3.26Å; S352-F354 PolarHBondContact O-N 3.34Å; S352-A355 PolarHBondContact O-N 2.97Å; S352-A355 VanDerWaalsContact O-N 3.12Å; S352-A355 VanDerWaalsContact OG-CB 3.25Å; S352-A355 WeakPolarHBondContact OG-CB 3.37Å; S352-A355 PolarHBondContact OG-N 3.42Å; S352-R356 PolarHBondContact O-N 2.92Å; S352-R356 VanDerWaalsContact O-N 3.13Å
353	R	75.1	Confident	82.4	Confident	112 Å²	112	62 Å²	62	42%	0.423	31%	0.305	S	S	.	.	H	α-helix	trans	-51.9	-46.1	-179.7	-73.6	179.8	-86.7	159.9	-3.2	111.7	D144 R356 V357	D144-R353 WeakPolarHBondContact OD2-CD 3.47Å; D144-R353 IonicContact OD2-CZ 3.65Å; D144-R353 IonicContact OD2-NE 3.9Å; D144-R353 IonicContact OD2-NH1 2.67Å; D144-R353 PolarHBondContact OD2-NH1 3.31Å; R353-R356 PolarHBondContact O-N 3.33Å; R353-V357 WeakPolarHBondContact O-CG2 3.42Å; R353-V357 PolarHBondContact O-N 3.48Å; R353-V357 VanDerWaalsContact O-N 3.07Å
354	F	78.5	Confident	82.2	Confident	95 Å²	95	61.4 Å²	61.4	42%	0.417	30%	0.302	S	S	.	.	H	α-helix	trans	-57.7	-49.2	176	-72.2	-93.4	0	0	0	113.5	L141 S352 R356 V357 L358	L141-F354 HydrophobicContact CB-CD1 4.45Å; L141-F354 HydrophobicContact CB-CE1 3.91Å; L141-F354 HydrophobicContact CB-CZ 4.35Å; L141-F354 HydrophobicContact CD1-CD1 3.77Å; L141-F354 HydrophobicContact CD1-CE1 4.04Å; L141-F354 HydrophobicContact CD2-CD1 4.2Å; L141-F354 HydrophobicContact CD2-CE1 4.32Å; L141-F354 HydrophobicContact CD2-CG 4.38Å; L141-F354 HydrophobicContact CG-CD1 4.38Å; L141-F354 HydrophobicContact CG-CE1 4.33Å; S352-F354 VanDerWaalsContact C-N 3.26Å; S352-F354 PolarHBondContact O-N 3.34Å; F354-R356 VanDerWaalsContact C-N 3.35Å; F354-R356 PolarHBondContact O-N 2.97Å; F354-V357 PolarHBondContact O-N 3.23Å; F354-L358 WeakPolarHBondContact O-CB 3.37Å; F354-L358 VanDerWaalsContact O-CG 3.29Å; F354-L358 WeakPolarHBondContact O-CG 3.35Å; F354-L358 PolarHBondContact O-N 3.4Å
355	A	81.9	Confident	82.1	Confident	42 Å²	42	59.5 Å²	59.5	35%	0.347	29%	0.293	S	S	.	.	H	α-helix	trans	-66.3	-37.1	-177.6	0	0	0	0	0	112.4	W351 S352 L359	W351-A355 HydrophobicContact CE3-CB 4.32Å; S352-A355 PolarHBondContact O-N 2.97Å; S352-A355 VanDerWaalsContact O-N 3.12Å; S352-A355 VanDerWaalsContact OG-CB 3.25Å; S352-A355 WeakPolarHBondContact OG-CB 3.37Å; S352-A355 PolarHBondContact OG-N 3.42Å; A355-L359 WeakPolarHBondContact O-CB 3.19Å; A355-L359 PolarHBondContact O-N 3.4Å
356	R	80.2	Confident	82.1	Confident	4 Å²	4	64.7 Å²	64.7	2%	0.015	32%	0.32	C	S	.	.	H	α-helix	trans	-62.7	-55.1	175.1	178.5	-179.1	-65.8	137	-5	111.4	Q340 M343 E344 L349 W351 S352 R353 F354 L358 L359 T360	Q340-R356 VanDerWaalsContact CG-NH1 3.3Å; M343-R356 HydrophobicContact SD-CG 3.73Å; M343-R356 PolarHBondContact SD-NE 3.16Å; E344-R356 IonicContact OE1-CZ 3.64Å; E344-R356 IonicContact OE1-NH1 2.76Å; E344-R356 PolarHBondContact OE1-NH1 3.36Å; E344-R356 IonicContact OE1-NH2 2.7Å; E344-R356 PolarHBondContact OE1-NH2 3.15Å; L349-R356 PolarHBondContact O-NH2 3.05Å; W351-R356 HydrophobicContact CE3-CB 4.28Å; S352-R356 PolarHBondContact O-N 2.92Å; S352-R356 VanDerWaalsContact O-N 3.13Å; R353-R356 PolarHBondContact O-N 3.33Å; F354-R356 VanDerWaalsContact C-N 3.35Å; F354-R356 PolarHBondContact O-N 2.97Å; R356-L358 PolarHBondContact O-N 3.23Å; R356-L359 PolarHBondContact O-N 3.46Å; R356-L359 VanDerWaalsContact O-N 3.15Å; R356-T360 PolarHBondContact O-N 3.23Å; R356-T360 PolarHBondContact O-OG1 2.86Å
357	V	79.1	Confident	81.8	Confident	9 Å²	9	66.8 Å²	66.8	6%	0.055	33%	0.334	C	S	.	.	H	α-helix	trans	-62.5	-43	-176.8	171.8	0	0	0	0	111.1	T137 L141 T336 R353 F354 L359 T360 R361	T137-V357 HydrophobicContact CG2-CG1 3.49Å; T137-V357 VanDerWaalsContact CG2-CG1 3.49Å; L141-V357 HydrophobicContact CD1-CB 4.4Å; L141-V357 HydrophobicContact CD1-CG1 4.05Å; L141-V357 HydrophobicContact CD2-CB 4.12Å; L141-V357 HydrophobicContact CD2-CG1 4.27Å; L141-V357 HydrophobicContact CD2-CG2 4.06Å; L141-V357 HydrophobicContact CG-CG1 4.17Å; T336-V357 HydrophobicContact CG2-CB 4.35Å; T336-V357 HydrophobicContact CG2-CG1 3.87Å; T336-V357 HydrophobicContact CG2-CG2 3.8Å; R353-V357 WeakPolarHBondContact O-CG2 3.42Å; R353-V357 PolarHBondContact O-N 3.48Å; R353-V357 VanDerWaalsContact O-N 3.07Å; F354-V357 PolarHBondContact O-N 3.23Å; V357-L359 VanDerWaalsContact C-N 3.33Å; V357-L359 PolarHBondContact O-N 2.92Å; V357-T360 PolarHBondContact O-OG1 3.11Å; V357-R361 HydrophobicContact CG1-CG 4.26Å; V357-R361 VanDerWaalsContact O-CB 3.22Å; V357-R361 WeakPolarHBondContact O-CB 3.48Å; V357-R361 WeakPolarHBondContact O-CG 3.43Å; V357-R361 PolarHBondContact O-N 2.84Å
358	L	82.3	Confident	81.7	Confident	66 Å²	66	64.7 Å²	64.7	35%	0.346	32%	0.323	S	S	.	.	H	α-helix	trans	-63.1	-36.6	175.3	-73	169.9	0	0	0	112.5	F138 F354 R356 S362	F138-L358 HydrophobicContact CE1-CD2 4.31Å; F138-L358 HydrophobicContact CZ-CD2 4.19Å; F354-L358 WeakPolarHBondContact O-CB 3.37Å; F354-L358 VanDerWaalsContact O-CG 3.29Å; F354-L358 WeakPolarHBondContact O-CG 3.35Å; F354-L358 PolarHBondContact O-N 3.4Å; R356-L358 PolarHBondContact O-N 3.23Å; L358-S362 VanDerWaalsContact O-CB 3.23Å; L358-S362 WeakPolarHBondContact O-CB 3.48Å; L358-S362 PolarHBondContact O-N 2.99Å; L358-S362 PolarHBondContact O-OG 3.47Å
359	L	85.1	Confident	81.7	Confident	83 Å²	83	60 Å²	60	44%	0.435	30%	0.304	S	S	.	.	H	α-helix	trans	-66	-53.8	176.4	-178	72.5	0	0	0	111.5	W351 A355 R356 V357 R361 S362 C363	W351-L359 HydrophobicContact CH2-CD2 3.82Å; W351-L359 HydrophobicContact CZ3-CB 4.14Å; W351-L359 HydrophobicContact CZ3-CD2 3.62Å; W351-L359 HydrophobicContact CZ3-CG 4.46Å; A355-L359 WeakPolarHBondContact O-CB 3.19Å; A355-L359 PolarHBondContact O-N 3.4Å; R356-L359 PolarHBondContact O-N 3.46Å; R356-L359 VanDerWaalsContact O-N 3.15Å; V357-L359 VanDerWaalsContact C-N 3.33Å; V357-L359 PolarHBondContact O-N 2.92Å; L359-R361 VanDerWaalsContact C-N 3.32Å; L359-R361 PolarHBondContact O-N 3.13Å; L359-S362 PolarHBondContact O-N 3.19Å; L359-S362 VanDerWaalsContact O-N 3.17Å; L359-C363 PolarHBondContact O-N 2.91Å; L359-C363 PolarHBondContact O-SG 3.03Å; L359-C363 VanDerWaalsContact O-SG 3.35Å
360	T	80.1	Confident	81.9	Confident	11 Å²	11	60.1 Å²	60.1	7%	0.067	31%	0.305	C	S	.	.	H	α-helix	trans	-62	-42.6	-176.5	56.2	0	0	0	0	111.1	R356 V357 C363 A364	R356-T360 PolarHBondContact O-N 3.23Å; R356-T360 PolarHBondContact O-OG1 2.86Å; V357-T360 PolarHBondContact O-OG1 3.11Å; T360-C363 WeakPolarHBondContact O-CB 3.24Å; T360-C363 PolarHBondContact O-N 2.95Å; T360-A364 PolarHBondContact O-N 2.65Å; T360-A364 VanDerWaalsContact O-N 3.08Å
361	R	84.8	Confident	82.2	Confident	5 Å²	5	50.8 Å²	50.8	2%	0.019	27%	0.274	C	S	.	.	H	α-helix	trans	-62	-43	173.8	-70.9	-76.4	129.1	160.3	-4.3	112.4	D105 E108 T137 V357 L359 C363 A364 I365	D105-R361 IonicContact OD1-CZ 3.2Å; D105-R361 IonicContact OD1-NE 3.71Å; D105-R361 PolarHBondContact OD1-NE 2.89Å; D105-R361 IonicContact OD1-NH1 3.16Å; D105-R361 IonicContact OD1-NH2 3.67Å; D105-R361 PolarHBondContact OD1-NH2 2.91Å; D105-R361 VanDerWaalsContact OD1-NH2 3.13Å; D105-R361 IonicContact OD2-CZ 3.96Å; D105-R361 IonicContact OD2-NE 2.73Å; D105-R361 PolarHBondContact OD2-NE 3.48Å; D105-R361 IonicContact OD2-NH2 2.7Å; D105-R361 PolarHBondContact OD2-NH2 3.35Å; E108-R361 VanDerWaalsContact CD-NH1 3.31Å; E108-R361 IonicContact OE1-CZ 2.9Å; E108-R361 IonicContact OE1-NH1 3.32Å; E108-R361 PolarHBondContact OE1-NH1 2.97Å; E108-R361 IonicContact OE1-NH2 2.99Å; E108-R361 IonicContact OE2-CZ 3.98Å; E108-R361 IonicContact OE2-NH1 3.12Å; E108-R361 PolarHBondContact OE2-NH1 2.85Å; E108-R361 VanDerWaalsContact OE2-NH1 3.16Å; E108-R361 IonicContact OE2-NH2 2.83Å; E108-R361 PolarHBondContact OE2-NH2 3.48Å; T137-R361 HydrophobicContact CG2-CB 4.39Å; T137-R361 HydrophobicContact CG2-CG 3.76Å; T137-R361 WeakPolarHBondContact OG1-CD 3.34Å; V357-R361 HydrophobicContact CG1-CG 4.26Å; V357-R361 VanDerWaalsContact O-CB 3.22Å; V357-R361 WeakPolarHBondContact O-CB 3.48Å; V357-R361 WeakPolarHBondContact O-CG 3.43Å; V357-R361 PolarHBondContact O-N 2.84Å; L359-R361 VanDerWaalsContact C-N 3.32Å; L359-R361 PolarHBondContact O-N 3.13Å; R361-C363 VanDerWaalsContact C-N 3.3Å; R361-C363 PolarHBondContact O-N 3.02Å; R361-A364 PolarHBondContact O-N 3.48Å; R361-I365 HydrophobicContact CB-CD1 4.24Å; R361-I365 VanDerWaalsContact O-CB 3.25Å; R361-I365 WeakPolarHBondContact O-CB 3.32Å; R361-I365 WeakPolarHBondContact O-CG1 3.37Å; R361-I365 PolarHBondContact O-N 3.01Å
362	S	86.1	Confident	82.4	Confident	71 Å²	71	46 Å²	46	50%	0.497	26%	0.26	S	S	.	.	H	α-helix	trans	-61.6	-40.5	175.8	-61.7	0	0	0	0	111.8	L358 L359 A364 L366	L358-S362 VanDerWaalsContact O-CB 3.23Å; L358-S362 WeakPolarHBondContact O-CB 3.48Å; L358-S362 PolarHBondContact O-N 2.99Å; L358-S362 PolarHBondContact O-OG 3.47Å; L359-S362 PolarHBondContact O-N 3.19Å; L359-S362 VanDerWaalsContact O-N 3.17Å; S362-A364 VanDerWaalsContact C-N 3.32Å; S362-A364 PolarHBondContact O-N 2.94Å; S362-L366 WeakPolarHBondContact O-CB 3.37Å; S362-L366 PolarHBondContact O-N 3.06Å; S362-L366 VanDerWaalsContact O-N 3.07Å
363	C	86.5	Confident	82.4	Confident	64 Å²	64	46 Å²	46	43%	0.432	26%	0.257	S	S	.	.	H	α-helix	trans	-66.6	-28.8	177.4	-69.5	0	0	0	0	113.6	V102 L359 T360 R361 P367	V102-C363 HydrophobicContact CG1-CB 4.24Å; V102-C363 HydrophobicContact CG2-CB 4.31Å; L359-C363 PolarHBondContact O-N 2.91Å; L359-C363 PolarHBondContact O-SG 3.03Å; L359-C363 VanDerWaalsContact O-SG 3.35Å; T360-C363 WeakPolarHBondContact O-CB 3.24Å; T360-C363 PolarHBondContact O-N 2.95Å; R361-C363 VanDerWaalsContact C-N 3.3Å; R361-C363 PolarHBondContact O-N 3.02Å; C363-P367 WeakPolarHBondContact O-CD 3.34Å; C363-P367 VanDerWaalsContact O-CG 3.28Å; C363-P367 WeakPolarHBondContact O-CG 3.27Å
364	A	84.6	Confident	82.5	Confident	0 Å²	0	48.1 Å²	48.1	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-88.9	-41.3	177	0	0	0	0	0	113.3	V102 D105 M106 T360 R361 S362 P367 T368	V102-A364 HydrophobicContact CG1-CB 4.31Å; D105-A364 HydrophobicContact CB-CB 3.68Å; D105-A364 WeakPolarHBondContact OD1-CB 3.43Å; M106-A364 HydrophobicContact CG-CB 3.72Å; T360-A364 PolarHBondContact O-N 2.65Å; T360-A364 VanDerWaalsContact O-N 3.08Å; R361-A364 PolarHBondContact O-N 3.48Å; S362-A364 VanDerWaalsContact C-N 3.32Å; S362-A364 PolarHBondContact O-N 2.94Å; A364-P367 WeakPolarHBondContact O-CD 3.21Å; A364-P367 WeakPolarHBondContact O-CG 3.26Å; A364-T368 WeakPolarHBondContact O-CB 3.36Å; A364-T368 PolarHBondContact O-N 2.92Å; A364-T368 PolarHBondContact O-OG1 3.32Å
365	I	86.9	Confident	82.1	Confident	14 Å²	14	51.2 Å²	51.2	7%	0.072	28%	0.278	C	S	.	.	H	α-helix	trans	-70.3	-40.5	-178.3	-67.3	172.1	0	0	0	110.7	V109 V130 I134 R361 T368 V369	V109-I365 HydrophobicContact CG1-CG1 4.33Å; V109-I365 HydrophobicContact CG2-CG1 4.07Å; V130-I365 HydrophobicContact CG1-CG2 4.03Å; I134-I365 HydrophobicContact CG1-CD1 3.69Å; I134-I365 HydrophobicContact CG1-CG2 4.46Å; R361-I365 HydrophobicContact CB-CD1 4.24Å; R361-I365 VanDerWaalsContact O-CB 3.25Å; R361-I365 WeakPolarHBondContact O-CB 3.32Å; R361-I365 WeakPolarHBondContact O-CG1 3.37Å; R361-I365 PolarHBondContact O-N 3.01Å; I365-T368 PolarHBondContact O-N 2.64Å; I365-V369 HydrophobicContact CG2-CG2 3.85Å; I365-V369 WeakPolarHBondContact O-CB 3.37Å; I365-V369 WeakPolarHBondContact O-CG2 3.38Å; I365-V369 PolarHBondContact O-N 2.74Å
366	L	86.8	Confident	81.3	Confident	109 Å²	109	55.5 Å²	55.5	57%	0.571	30%	0.295	S	S	*	.	H	α-helix	trans	-56.5	-54.5	-178.9	-178.5	65.3	0	0	0	114.1	S362 T368 V369 L370	S362-L366 WeakPolarHBondContact O-CB 3.37Å; S362-L366 PolarHBondContact O-N 3.06Å; S362-L366 VanDerWaalsContact O-N 3.07Å; L366-T368 VanDerWaalsContact C-N 3.32Å; L366-T368 PolarHBondContact O-N 3.14Å; L366-V369 PolarHBondContact O-N 3.42Å; L366-L370 HydrophobicContact CD1-CD1 4.41Å; L366-L370 HydrophobicContact CG-CD1 4.33Å; L366-L370 VanDerWaalsContact O-CG 3.29Å; L366-L370 WeakPolarHBondContact O-CG 3.34Å; L366-L370 PolarHBondContact O-N 3.29Å
367	P	83.5	Confident	80.3	Confident	44 Å²	44	59 Å²	59	29%	0.286	31%	0.314	S	S	.	.	H	α-helix	trans	-64.5	-37	176.8	25.4	-34.1	0	0	0	112.1	M106 C363 A364 L370 V371	M106-P367 HydrophobicContact CE-CB 4.02Å; M106-P367 HydrophobicContact CE-CG 3.79Å; M106-P367 HydrophobicContact SD-CG 3.84Å; C363-P367 WeakPolarHBondContact O-CD 3.34Å; C363-P367 VanDerWaalsContact O-CG 3.28Å; C363-P367 WeakPolarHBondContact O-CG 3.27Å; A364-P367 WeakPolarHBondContact O-CD 3.21Å; A364-P367 WeakPolarHBondContact O-CG 3.26Å; P367-L370 PolarHBondContact O-N 2.87Å; P367-V371 WeakPolarHBondContact O-CG2 3.48Å; P367-V371 PolarHBondContact O-N 3.37Å
368	T	82.6	Confident	79.4	Confident	0 Å²	0	65 Å²	65	0%	0	34%	0.34	C	S	.	.	H	α-helix	trans	-65.9	-40.9	179.5	-50.6	0	0	0	0	111.7	V109 I110 V130 A364 I365 L366 V371 A372 L380	V109-T368 HydrophobicContact CG1-CG2 4.05Å; I110-T368 HydrophobicContact CD1-CG2 4.42Å; I110-T368 HydrophobicContact CG1-CG2 3.64Å; V130-T368 HydrophobicContact CG1-CG2 4.29Å; V130-T368 HydrophobicContact CG2-CG2 3.91Å; A364-T368 WeakPolarHBondContact O-CB 3.36Å; A364-T368 PolarHBondContact O-N 2.92Å; A364-T368 PolarHBondContact O-OG1 3.32Å; I365-T368 PolarHBondContact O-N 2.64Å; L366-T368 VanDerWaalsContact C-N 3.32Å; L366-T368 PolarHBondContact O-N 3.14Å; T368-V371 PolarHBondContact O-N 3.37Å; T368-A372 VanDerWaalsContact O-CB 3.27Å; T368-A372 WeakPolarHBondContact O-CB 3.48Å; T368-A372 PolarHBondContact O-N 3.16Å; T368-L380 HydrophobicContact CG2-CD2 4.28Å
369	V	85.3	Confident	78.6	Confident	25 Å²	25	64.8 Å²	64.8	15%	0.152	34%	0.339	C	S	.	.	H	α-helix	trans	-59.2	-48.4	170.3	155	0	0	0	0	111.1	W127 V130 L131 I365 L366 V371 A372 V373	W127-V369 VanDerWaalsContact NE1-CG1 3.28Å; V130-V369 HydrophobicContact CB-CG2 4.47Å; V130-V369 HydrophobicContact CG1-CG2 3.53Å; L131-V369 HydrophobicContact CD2-CG2 4.24Å; I365-V369 HydrophobicContact CG2-CG2 3.85Å; I365-V369 WeakPolarHBondContact O-CB 3.37Å; I365-V369 WeakPolarHBondContact O-CG2 3.38Å; I365-V369 PolarHBondContact O-N 2.74Å; L366-V369 PolarHBondContact O-N 3.42Å; V369-V371 VanDerWaalsContact C-N 3.33Å; V369-V371 PolarHBondContact O-N 3.08Å; V369-A372 PolarHBondContact O-N 3.05Å; V369-V373 HydrophobicContact CG1-CG2 4.4Å; V369-V373 WeakPolarHBondContact O-CG2 3.38Å; V369-V373 PolarHBondContact O-N 3.19Å
370	L	83.6	Confident	77.7	Confident	83 Å²	83	61.2 Å²	61.2	44%	0.435	32%	0.32	S	S	.	.	H	α-helix	trans	-61.4	-42.2	-178.4	-71.4	170.1	0	0	0	111.4	L366 P367 F374	L366-L370 HydrophobicContact CD1-CD1 4.41Å; L366-L370 HydrophobicContact CG-CD1 4.33Å; L366-L370 VanDerWaalsContact O-CG 3.29Å; L366-L370 WeakPolarHBondContact O-CG 3.34Å; L366-L370 PolarHBondContact O-N 3.29Å; P367-L370 PolarHBondContact O-N 2.87Å; L370-F374 HydrophobicContact CD2-CD2 4.13Å; L370-F374 HydrophobicContact CD2-CE2 3.79Å; L370-F374 WeakPolarHBondContact O-CB 3.1Å; L370-F374 VanDerWaalsContact O-CD2 3.3Å; L370-F374 WeakPolarHBondContact O-CD2 3.25Å; L370-F374 PolarHBondContact O-N 2.81Å; L370-F374 VanDerWaalsContact O-N 3.07Å
371	V	80.3	Confident	76.9	Confident	37 Å²	37	61.6 Å²	61.6	22%	0.224	32%	0.323	C	S	.	.	H	α-helix	trans	-65.4	-46.6	173.6	179.2	0	0	0	0	110.5	P367 T368 V369 V373 F374 R375 D379 L380 L383	P367-V371 WeakPolarHBondContact O-CG2 3.48Å; P367-V371 PolarHBondContact O-N 3.37Å; T368-V371 PolarHBondContact O-N 3.37Å; V369-V371 VanDerWaalsContact C-N 3.33Å; V369-V371 PolarHBondContact O-N 3.08Å; V371-V373 VanDerWaalsContact C-N 3.29Å; V371-V373 PolarHBondContact O-N 3.2Å; V371-F374 PolarHBondContact O-N 3.42Å; V371-R375 HydrophobicContact CG1-CB 4.15Å; V371-R375 HydrophobicContact CG1-CG 4.48Å; V371-R375 WeakPolarHBondContact O-CA 3.45Å; V371-R375 VanDerWaalsContact O-CB 3.32Å; V371-R375 WeakPolarHBondContact O-CB 3.39Å; V371-R375 PolarHBondContact O-N 3.42Å; V371-D379 HydrophobicContact CG1-CB 4.2Å; V371-L380 HydrophobicContact CB-CD2 4.05Å; V371-L380 HydrophobicContact CG1-CD2 3.71Å; V371-L380 HydrophobicContact CG1-CG 3.91Å; V371-L383 HydrophobicContact CG2-CD2 4.27Å
372	A	78.1	Confident	76.2	Confident	19 Å²	19	63.4 Å²	63.4	16%	0.157	34%	0.343	C	S	.	.	H	α-helix	trans	-65.8	-22.3	-178.4	0	0	0	0	0	115.5	W127 T368 V369 L380	W127-A372 HydrophobicContact CB-CB 4.17Å; T368-A372 VanDerWaalsContact O-CB 3.27Å; T368-A372 WeakPolarHBondContact O-CB 3.48Å; T368-A372 PolarHBondContact O-N 3.16Å; V369-A372 PolarHBondContact O-N 3.05Å; A372-L380 HydrophobicContact CB-CD1 4.01Å; A372-L380 HydrophobicContact CB-CD2 4.36Å
373	V	80.2	Confident	75.7	Confident	74 Å²	74	61.3 Å²	61.3	45%	0.448	33%	0.326	S	S	.	.	H	α-helix	trans	-91.3	-41.8	176.2	173.6	0	0	0	0	112.1	W127 V369 V371	W127-V373 HydrophobicContact CB-CG2 4.23Å; W127-V373 HydrophobicContact CD2-CG2 3.84Å; W127-V373 HydrophobicContact CG-CG2 3.51Å; V369-V373 HydrophobicContact CG1-CG2 4.4Å; V369-V373 WeakPolarHBondContact O-CG2 3.38Å; V369-V373 PolarHBondContact O-N 3.19Å; V371-V373 VanDerWaalsContact C-N 3.29Å; V371-V373 PolarHBondContact O-N 3.2Å
374	F	75.9	Confident	75.3	Confident	155 Å²	155	59.1 Å²	59.1	68%	0.68	31%	0.31	S	S	*	.	H	α-helix	trans	-99.7	-7.4	-170.2	-66.1	-68.4	0	0	0	114.4	L370 V371	L370-F374 HydrophobicContact CD2-CD2 4.13Å; L370-F374 HydrophobicContact CD2-CE2 3.79Å; L370-F374 WeakPolarHBondContact O-CB 3.1Å; L370-F374 VanDerWaalsContact O-CD2 3.3Å; L370-F374 WeakPolarHBondContact O-CD2 3.25Å; L370-F374 PolarHBondContact O-N 2.81Å; L370-F374 VanDerWaalsContact O-N 3.07Å; V371-F374 PolarHBondContact O-N 3.42Å
375	R	69.9	Low	74.9	Confident	160 Å²	160	63.4 Å²	63.4	60%	0.604	33%	0.333	S	S	*	.	S	Bend	trans	-132.9	158.8	-177.7	-62.7	-58.3	-169	113	-10.5	113.1	V371 D379	V371-R375 HydrophobicContact CG1-CB 4.15Å; V371-R375 HydrophobicContact CG1-CG 4.48Å; V371-R375 WeakPolarHBondContact O-CA 3.45Å; V371-R375 VanDerWaalsContact O-CB 3.32Å; V371-R375 WeakPolarHBondContact O-CB 3.39Å; V371-R375 PolarHBondContact O-N 3.42Å; R375-D379 HydrophobicContact CB-CB 3.73Å; R375-D379 WeakPolarHBondContact CB-OD2 3.42Å; R375-D379 VanDerWaalsContact CD-OD2 3.23Å; R375-D379 WeakPolarHBondContact CD-OD2 3.37Å; R375-D379 HydrophobicContact CG-CB 4.29Å; R375-D379 WeakPolarHBondContact CG-OD2 3.36Å; R375-D379 IonicContact CZ-OD2 2.78Å; R375-D379 IonicContact NE-OD2 2.76Å; R375-D379 IonicContact NH1-OD2 3.81Å; R375-D379 PolarHBondContact NH1-OD2 3.36Å
376	D	65.8	Low	74.6	Confident	133 Å²	133	67.5 Å²	67.5	71%	0.711	35%	0.354	S	S	*	.			trans	-71.1	161.5	177.4	-75.3	-46.9	0	0	0	112.5	K378 D379	D376-K378 PolarHBondContact O-N 2.93Å; D376-D379 PolarHBondContact O-N 3.32Å
377	L	58.9	Low	74.5	Confident	78 Å²	78	62.7 Å²	62.7	41%	0.408	33%	0.329	S	S	.	.	H	α-helix	trans	-46.5	-36.5	178.5	-61.5	173.2	0	0	0	113.9	L126 Y302 D379 L380 S381	L126-L377 HydrophobicContact CD1-CD2 3.36Å; L126-L377 HydrophobicContact CG-CD2 3.85Å; Y302-L377 HydrophobicContact CE1-CD1 4.11Å; L377-D379 VanDerWaalsContact C-N 3.29Å; L377-D379 PolarHBondContact O-N 3.05Å; L377-L380 PolarHBondContact O-N 2.89Å; L377-S381 PolarHBondContact O-N 2.87Å; L377-S381 PolarHBondContact O-OG 3.45Å
378	K	60.9	Low	74.6	Confident	135 Å²	135	62 Å²	62	59%	0.587	32%	0.323	S	S	*	.	H	α-helix	trans	-63.8	-30.6	-178.7	-64	179.5	179.6	176.6	0	113.3	D376 L380 S381 G382	D376-K378 PolarHBondContact O-N 2.93Å; K378-L380 VanDerWaalsContact C-N 3.34Å; K378-S381 PolarHBondContact O-N 3.05Å; K378-G382 PolarHBondContact O-N 3.44Å; K378-G382 VanDerWaalsContact O-N 3.12Å
379	D	64.7	Low	74.5	Confident	61 Å²	61	63.5 Å²	63.5	33%	0.326	33%	0.332	S	S	.	.	H	α-helix	trans	-76	-23.9	-178.5	-72.1	9.6	0	0	0	111.4	V371 R375 D376 L377 L383	V371-D379 HydrophobicContact CG1-CB 4.2Å; R375-D379 HydrophobicContact CB-CB 3.73Å; R375-D379 WeakPolarHBondContact CB-OD2 3.42Å; R375-D379 VanDerWaalsContact CD-OD2 3.23Å; R375-D379 WeakPolarHBondContact CD-OD2 3.37Å; R375-D379 HydrophobicContact CG-CB 4.29Å; R375-D379 WeakPolarHBondContact CG-OD2 3.36Å; R375-D379 IonicContact CZ-OD2 2.78Å; R375-D379 IonicContact NE-OD2 2.76Å; R375-D379 IonicContact NH1-OD2 3.81Å; R375-D379 PolarHBondContact NH1-OD2 3.36Å; D376-D379 PolarHBondContact O-N 3.32Å; L377-D379 VanDerWaalsContact C-N 3.29Å; L377-D379 PolarHBondContact O-N 3.05Å; D379-L383 WeakPolarHBondContact O-CB 3.46Å; D379-L383 PolarHBondContact O-N 3.06Å; D379-L383 VanDerWaalsContact O-N 3.13Å
380	L	66.6	Low	74.6	Confident	7 Å²	7	64.2 Å²	64.2	4%	0.037	34%	0.335	C	S	.	.	H	α-helix	trans	-74.8	-39.7	172.7	-74	164.1	0	0	0	112.1	I110 L126 T368 V371 A372 L377 K378 L383 N384	I110-L380 HydrophobicContact CG1-CD2 4.41Å; L126-L380 HydrophobicContact CB-CD1 4.31Å; L126-L380 HydrophobicContact CD1-CD1 3.48Å; L126-L380 VanDerWaalsContact CD1-CD1 3.48Å; T368-L380 HydrophobicContact CG2-CD2 4.28Å; V371-L380 HydrophobicContact CB-CD2 4.05Å; V371-L380 HydrophobicContact CG1-CD2 3.71Å; V371-L380 HydrophobicContact CG1-CG 3.91Å; A372-L380 HydrophobicContact CB-CD1 4.01Å; A372-L380 HydrophobicContact CB-CD2 4.36Å; L377-L380 PolarHBondContact O-N 2.89Å; K378-L380 VanDerWaalsContact C-N 3.34Å; L380-L383 WeakPolarHBondContact O-CB 3.09Å; L380-L383 PolarHBondContact O-N 3.29Å; L380-N384 PolarHBondContact O-N 3.09Å
381	S	64.1	Low	74.9	Confident	20 Å²	20	60.3 Å²	60.3	14%	0.14	31%	0.314	C	S	.	.	H	α-helix	trans	-63.1	-49.1	174.7	-48	0	0	0	0	111	D300 L377 K378 L383 N384 D385	D300-S381 WeakPolarHBondContact OD1-CB 3.46Å; D300-S381 PolarHBondContact OD1-OG 2.87Å; D300-S381 PolarHBondContact OD2-OG 3.34Å; L377-S381 PolarHBondContact O-N 2.87Å; L377-S381 PolarHBondContact O-OG 3.45Å; K378-S381 PolarHBondContact O-N 3.05Å; S381-L383 VanDerWaalsContact C-N 3.25Å; S381-L383 PolarHBondContact O-N 3.2Å; S381-N384 WeakPolarHBondContact O-CB 3.28Å; S381-N384 PolarHBondContact O-N 3.31Å; S381-D385 PolarHBondContact O-N 2.97Å
382	G	68.9	Low	75.2	Confident	42 Å²	42	58.7 Å²	58.7	43%	0.433	31%	0.305	S	S	.	.	H	α-helix	trans	-63.5	-28.4	175.9	0	0	0	0	0	113.9	K378 L386	K378-G382 PolarHBondContact O-N 3.44Å; K378-G382 VanDerWaalsContact O-N 3.12Å; G382-L386 PolarHBondContact O-N 3.48Å; G382-L386 VanDerWaalsContact O-N 3.1Å
383	L	75.6	Confident	75.7	Confident	28 Å²	28	59.6 Å²	59.6	15%	0.147	31%	0.307	C	S	.	.	H	α-helix	trans	-66.1	-39	171.2	177.4	61.4	0	0	0	111.8	M106 I110 V371 D379 L380 S381 D385 L386 L387	M106-L383 HydrophobicContact CE-CD1 4.21Å; M106-L383 HydrophobicContact CE-CD2 3.88Å; M106-L383 HydrophobicContact CE-CG 4.38Å; I110-L383 HydrophobicContact CD1-CD2 3.99Å; I110-L383 HydrophobicContact CD1-CG 4.16Å; V371-L383 HydrophobicContact CG2-CD2 4.27Å; D379-L383 WeakPolarHBondContact O-CB 3.46Å; D379-L383 PolarHBondContact O-N 3.06Å; D379-L383 VanDerWaalsContact O-N 3.13Å; L380-L383 WeakPolarHBondContact O-CB 3.09Å; L380-L383 PolarHBondContact O-N 3.29Å; S381-L383 VanDerWaalsContact C-N 3.25Å; S381-L383 PolarHBondContact O-N 3.2Å; L383-D385 PolarHBondContact O-N 3.3Å; L383-L386 HydrophobicContact CD1-CD2 4.44Å; L383-L386 PolarHBondContact O-N 2.87Å; L383-L387 HydrophobicContact CD1-CD1 4.28Å; L383-L387 HydrophobicContact CD1-CG 4.3Å; L383-L387 HydrophobicContact CG-CD1 4.04Å; L383-L387 WeakPolarHBondContact O-CB 3.26Å; L383-L387 WeakPolarHBondContact O-CG 3.49Å; L383-L387 PolarHBondContact O-N 3.23Å
384	N	78.4	Confident	76.3	Confident	17 Å²	17	56.4 Å²	56.4	9%	0.091	29%	0.287	C	S	.	.	H	α-helix	trans	-62.3	-41.2	176.3	-178.6	49	0	0	0	112.4	Q107 L380 S381 L387 N388	Q107-N384 WeakPolarHBondContact CG-OD1 3.19Å; Q107-N384 PolarHBondContact NE2-O 3.46Å; Q107-N384 PolarHBondContact NE2-OD1 2.91Å; Q107-N384 VanDerWaalsContact NE2-OD1 3.16Å; L380-N384 PolarHBondContact O-N 3.09Å; S381-N384 WeakPolarHBondContact O-CB 3.28Å; S381-N384 PolarHBondContact O-N 3.31Å; N384-L387 PolarHBondContact O-N 2.99Å; N384-N388 PolarHBondContact O-N 3.44Å; N384-N388 PolarHBondContact O-ND2 3.35Å
385	D	76.1	Confident	77	Confident	91 Å²	91	49.2 Å²	49.2	49%	0.487	26%	0.256	S	S	.	.	H	α-helix	trans	-66.3	-41.7	176.1	-70.1	-25.7	0	0	0	112.1	S381 L383 L387 N388 V389	S381-D385 PolarHBondContact O-N 2.97Å; L383-D385 PolarHBondContact O-N 3.3Å; D385-L387 PolarHBondContact O-N 3.2Å; D385-N388 PolarHBondContact O-N 3.01Å; D385-V389 WeakPolarHBondContact O-CG2 3.2Å; D385-V389 PolarHBondContact O-N 3.41Å
386	L	79.9	Confident	78.1	Confident	99 Å²	99	41.6 Å²	41.6	52%	0.518	23%	0.227	S	C	.	.	H	α-helix	trans	-58.9	-38.1	172.8	-173.9	72.5	0	0	0	111.7	G382 L383 V389 L390	G382-L386 PolarHBondContact O-N 3.48Å; G382-L386 VanDerWaalsContact O-N 3.1Å; L383-L386 HydrophobicContact CD1-CD2 4.44Å; L383-L386 PolarHBondContact O-N 2.87Å; L386-V389 PolarHBondContact O-N 2.9Å; L386-L390 WeakPolarHBondContact O-CB 3.44Å; L386-L390 PolarHBondContact O-N 2.84Å
387	L	85.6	Confident	79.4	Confident	9 Å²	9	35.3 Å²	35.3	5%	0.047	19%	0.194	C	C	.	.	H	α-helix	trans	-69.7	-37.8	177.3	-69.5	167.2	0	0	0	112.2	M106 Q107 I110 L383 N384 D385 V389 L390 Q391	M106-L387 HydrophobicContact CB-CD1 3.63Å; M106-L387 HydrophobicContact CE-CD1 4.34Å; M106-L387 HydrophobicContact SD-CD2 4.4Å; Q107-L387 HydrophobicContact CG-CB 3.51Å; Q107-L387 HydrophobicContact CG-CD1 3.64Å; Q107-L387 HydrophobicContact CG-CG 4.2Å; I110-L387 HydrophobicContact CD1-CD1 4.31Å; L383-L387 HydrophobicContact CD1-CD1 4.28Å; L383-L387 HydrophobicContact CD1-CG 4.3Å; L383-L387 HydrophobicContact CG-CD1 4.04Å; L383-L387 WeakPolarHBondContact O-CB 3.26Å; L383-L387 WeakPolarHBondContact O-CG 3.49Å; L383-L387 PolarHBondContact O-N 3.23Å; N384-L387 PolarHBondContact O-N 2.99Å; D385-L387 PolarHBondContact O-N 3.2Å; L387-V389 VanDerWaalsContact C-N 3.34Å; L387-V389 PolarHBondContact O-N 2.83Å; L387-L390 HydrophobicContact CD2-CD2 4.11Å; L387-L390 WeakPolarHBondContact O-CB 3.42Å; L387-L390 PolarHBondContact O-N 3.4Å; L387-Q391 WeakPolarHBondContact O-CG 3.48Å; L387-Q391 PolarHBondContact O-N 3.25Å
388	N	84.8	Confident	81.1	Confident	30 Å²	30	31.6 Å²	31.6	16%	0.16	17%	0.174	C	C	.	.	H	α-helix	trans	-60.4	-43.7	171.8	-76.1	-42.2	0	0	0	111.8	Q107 N384 D385 L390 Q391 S392	Q107-N388 PolarHBondContact NE2-OD1 3.04Å; N384-N388 PolarHBondContact O-N 3.44Å; N384-N388 PolarHBondContact O-ND2 3.35Å; D385-N388 PolarHBondContact O-N 3.01Å; N388-L390 VanDerWaalsContact C-N 3.33Å; N388-Q391 PolarHBondContact O-N 3.31Å; N388-S392 PolarHBondContact O-N 3.02Å; N388-S392 VanDerWaalsContact O-N 3.13Å
389	V	81.6	Confident	82.6	Confident	30 Å²	30	25.2 Å²	25.2	18%	0.182	15%	0.146	C	C	.	.	H	α-helix	trans	-63.3	-39.8	174.6	171.5	0	0	0	0	111.2	D385 L386 L387 S392 L393 F439	D385-V389 WeakPolarHBondContact O-CG2 3.2Å; D385-V389 PolarHBondContact O-N 3.41Å; L386-V389 PolarHBondContact O-N 2.9Å; L387-V389 VanDerWaalsContact C-N 3.34Å; L387-V389 PolarHBondContact O-N 2.83Å; V389-S392 PolarHBondContact O-N 3.04Å; V389-L393 PolarHBondContact O-N 3.4Å; V389-F439 HydrophobicContact CG1-CD2 4.28Å; V389-F439 HydrophobicContact CG1-CE1 4.17Å; V389-F439 HydrophobicContact CG1-CE2 3.29Å; V389-F439 HydrophobicContact CG1-CZ 3.23Å
390	L	86.8	Confident	84	Confident	41 Å²	41	22.3 Å²	22.3	22%	0.215	13%	0.131	C	C	.	.	H	α-helix	trans	-61.4	-42.8	173.7	-179.9	65.6	0	0	0	112.1	L99 L386 L387 N388 S392 L393 L394	L99-L390 HydrophobicContact CD2-CD1 4.31Å; L99-L390 HydrophobicContact CG-CD2 4.37Å; L386-L390 WeakPolarHBondContact O-CB 3.44Å; L386-L390 PolarHBondContact O-N 2.84Å; L387-L390 HydrophobicContact CD2-CD2 4.11Å; L387-L390 WeakPolarHBondContact O-CB 3.42Å; L387-L390 PolarHBondContact O-N 3.4Å; N388-L390 VanDerWaalsContact C-N 3.33Å; L390-S392 VanDerWaalsContact C-N 3.31Å; L390-S392 PolarHBondContact O-N 3.31Å; L390-L393 WeakPolarHBondContact O-CB 3.43Å; L390-L393 PolarHBondContact O-N 3.26Å; L390-L394 HydrophobicContact CD1-CD1 3.82Å; L390-L394 HydrophobicContact CD1-CG 4.11Å; L390-L394 HydrophobicContact CD2-CD1 4.48Å; L390-L394 HydrophobicContact CG-CD1 3.77Å; L390-L394 HydrophobicContact CG-CG 4.41Å; L390-L394 VanDerWaalsContact O-CG 3.23Å; L390-L394 WeakPolarHBondContact O-CG 3.44Å; L390-L394 PolarHBondContact O-N 2.91Å
391	Q	89.5	Confident	85.3	Confident	0 Å²	0	22 Å²	22	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-59.2	-44	174.6	-62.4	-55.2	-24.3	0	0	111.4	A100 S104 P210 L387 N388 L393 L394 L395	A100-Q391 PolarHBondContact O-NE2 3.28Å; A100-Q391 PolarHBondContact O-OE1 3.06Å; S104-Q391 VanDerWaalsContact N-NE2 3.2Å; P210-Q391 VanDerWaalsContact CD-OE1 3.32Å; P210-Q391 WeakPolarHBondContact CG-O 3.35Å; L387-Q391 WeakPolarHBondContact O-CG 3.48Å; L387-Q391 PolarHBondContact O-N 3.25Å; N388-Q391 PolarHBondContact O-N 3.31Å; Q391-L393 VanDerWaalsContact C-N 3.33Å; Q391-L393 PolarHBondContact O-N 2.86Å; Q391-L394 PolarHBondContact O-N 3.03Å; Q391-L395 PolarHBondContact O-N 3.35Å
392	S	87.3	Confident	86.6	Confident	3 Å²	3	21 Å²	21	2%	0.021	12%	0.122	C	C	.	.	H	α-helix	trans	-64.7	-36	176.6	-165.7	0	0	0	0	112.8	V201 N388 V389 L390 L394 L395 N436	V201-S392 VanDerWaalsContact CG1-OG 3.24Å; V201-S392 WeakPolarHBondContact CG1-OG 3.12Å; V201-S392 WeakPolarHBondContact O-CB 3.36Å; V201-S392 PolarHBondContact O-OG 3.36Å; N388-S392 PolarHBondContact O-N 3.02Å; N388-S392 VanDerWaalsContact O-N 3.13Å; V389-S392 PolarHBondContact O-N 3.04Å; L390-S392 VanDerWaalsContact C-N 3.31Å; L390-S392 PolarHBondContact O-N 3.31Å; S392-L394 VanDerWaalsContact C-N 3.33Å; S392-L395 WeakPolarHBondContact O-CB 3.24Å; S392-L395 PolarHBondContact O-N 3.33Å; S392-N436 PolarHBondContact O-OD1 3.12Å
393	L	88.5	Confident	87.8	Confident	38 Å²	38	19 Å²	19	20%	0.199	10%	0.102	C	C	.	.	H	α-helix	trans	-65.1	-37.4	175.7	-173.5	67.5	0	0	0	111.9	V389 L390 Q391 P396 N436 F439 V440 Y463	V389-L393 PolarHBondContact O-N 3.4Å; L390-L393 WeakPolarHBondContact O-CB 3.43Å; L390-L393 PolarHBondContact O-N 3.26Å; Q391-L393 VanDerWaalsContact C-N 3.33Å; Q391-L393 PolarHBondContact O-N 2.86Å; L393-P396 VanDerWaalsContact O-CD 3.25Å; L393-P396 WeakPolarHBondContact O-CD 3.48Å; L393-N436 VanDerWaalsContact CA-OD1 3.26Å; L393-N436 WeakPolarHBondContact CA-OD1 3.5Å; L393-N436 PolarHBondContact O-OD1 3.45Å; L393-F439 HydrophobicContact CD1-CD1 3.92Å; L393-F439 HydrophobicContact CD1-CE1 4.35Å; L393-V440 HydrophobicContact CD1-CG2 4.4Å; L393-Y463 HydrophobicContact CD1-CD2 4.43Å; L393-Y463 HydrophobicContact CD1-CE1 4.08Å; L393-Y463 HydrophobicContact CD1-CE2 3.72Å; L393-Y463 HydrophobicContact CG-CD2 4.41Å; L393-Y463 HydrophobicContact CG-CE2 3.73Å; L393-Y463 VanDerWaalsContact O-CE2 3.23Å; L393-Y463 WeakPolarHBondContact O-CE2 3.24Å; L393-Y463 PolarHBondContact O-OH 3.39Å
394	L	92.1	Very high	88.5	Confident	7 Å²	7	17.7 Å²	17.7	4%	0.037	10%	0.095	C	C	.	.	H	α-helix	trans	-84.8	-13.5	-177.9	-61.8	170.7	0	0	0	113.1	T96 L99 A100 P210 L390 Q391 S392 F397	T96-L394 HydrophobicContact CG2-CD2 4.19Å; L99-L394 HydrophobicContact CB-CD1 4.31Å; L99-L394 HydrophobicContact CD2-CD1 4.31Å; L99-L394 HydrophobicContact CD2-CD2 4.4Å; L99-L394 HydrophobicContact CG-CD1 4.11Å; A100-L394 HydrophobicContact CB-CB 4.33Å; A100-L394 HydrophobicContact CB-CD1 3.74Å; P210-L394 HydrophobicContact CG-CB 4.25Å; L390-L394 HydrophobicContact CD1-CD1 3.82Å; L390-L394 HydrophobicContact CD1-CG 4.11Å; L390-L394 HydrophobicContact CD2-CD1 4.48Å; L390-L394 HydrophobicContact CG-CD1 3.77Å; L390-L394 HydrophobicContact CG-CG 4.41Å; L390-L394 VanDerWaalsContact O-CG 3.23Å; L390-L394 WeakPolarHBondContact O-CG 3.44Å; L390-L394 PolarHBondContact O-N 2.91Å; Q391-L394 PolarHBondContact O-N 3.03Å; S392-L394 VanDerWaalsContact C-N 3.33Å; L394-F397 HydrophobicContact CB-CD2 4.43Å; L394-F397 HydrophobicContact CD2-CD2 3.99Å; L394-F397 HydrophobicContact CD2-CE2 4.05Å; L394-F397 WeakPolarHBondContact O-CB 3.39Å; L394-F397 WeakPolarHBondContact O-CD2 3.34Å; L394-F397 PolarHBondContact O-N 3.45Å
395	L	91.1	Very high	89.1	Confident	4 Å²	4	16.9 Å²	16.9	2%	0.021	9%	0.091	C	C	.	.	H	α-helix	trans	-51.4	-41.5	179.7	-175.8	58.7	0	0	0	116	V204 I208 I213 Q391 S392 F397 A398 V399 V432	V204-L395 HydrophobicContact CG1-CD2 4.19Å; I208-L395 HydrophobicContact CB-CD1 4.15Å; I208-L395 HydrophobicContact CB-CD2 4.3Å; I208-L395 HydrophobicContact CG2-CD1 3.63Å; I208-L395 HydrophobicContact CG2-CD2 4.41Å; I208-L395 WeakPolarHBondContact O-CD1 3.28Å; I213-L395 HydrophobicContact CD1-CD1 4.45Å; Q391-L395 PolarHBondContact O-N 3.35Å; S392-L395 WeakPolarHBondContact O-CB 3.24Å; S392-L395 PolarHBondContact O-N 3.33Å; L395-F397 PolarHBondContact O-N 3.46Å; L395-F397 VanDerWaalsContact O-N 3.16Å; L395-A398 PolarHBondContact O-N 3.13Å; L395-V399 HydrophobicContact CD1-CG2 3.44Å; L395-V399 VanDerWaalsContact CD1-CG2 3.44Å; L395-V399 HydrophobicContact CG-CG2 3.84Å; L395-V399 WeakPolarHBondContact O-CB 3.21Å; L395-V399 WeakPolarHBondContact O-CG2 3.43Å; L395-V399 PolarHBondContact O-N 3.46Å; L395-V432 HydrophobicContact CD2-CG2 4.45Å
396	P	92.9	Very high	89.8	Confident	0 Å²	0	12.6 Å²	12.6	0%	0	7%	0.067	C	C	.	.	H	α-helix	trans	-57.9	-31.2	177.7	-21.4	32	0	0	0	112.9	L393 A398 V399 L400 V432 N436 T467	L393-P396 VanDerWaalsContact O-CD 3.25Å; L393-P396 WeakPolarHBondContact O-CD 3.48Å; P396-A398 VanDerWaalsContact C-N 3.35Å; P396-A398 PolarHBondContact O-N 3.22Å; P396-V399 PolarHBondContact O-N 3.46Å; P396-L400 HydrophobicContact CB-CD1 3.91Å; P396-L400 HydrophobicContact CB-CG 4.32Å; P396-L400 VanDerWaalsContact O-CB 3.23Å; P396-L400 WeakPolarHBondContact O-CB 3.42Å; P396-L400 WeakPolarHBondContact O-CG 3.48Å; P396-L400 PolarHBondContact O-N 2.94Å; P396-V432 HydrophobicContact CB-CG1 3.92Å; P396-V432 HydrophobicContact CG-CG1 3.65Å; P396-N436 HydrophobicContact CG-CB 4.16Å; P396-N436 VanDerWaalsContact CG-ND2 3.33Å; P396-N436 WeakPolarHBondContact CG-ND2 3.24Å; P396-T467 HydrophobicContact CB-CG2 4.14Å
397	F	93.9	Very high	90.2	Very high	2 Å²	2	7.9 Å²	7.9	1%	0.009	4%	0.043	C	C	.	.	H	α-helix	trans	-70.1	-30.6	-177.8	-58.8	-48.8	0	0	0	112.6	L93 T96 I97 Y214 L394 L395 P401 Y463 L466 T467 L470	L93-F397 HydrophobicContact CD1-CB 3.62Å; L93-F397 HydrophobicContact CD1-CG 4.46Å; L93-F397 VanDerWaalsContact CD1-O 3.25Å; L93-F397 WeakPolarHBondContact CD1-O 3.09Å; T96-F397 HydrophobicContact CG2-CD2 3.75Å; T96-F397 HydrophobicContact CG2-CE2 3.68Å; T96-F397 HydrophobicContact CG2-CG 4.4Å; T96-F397 HydrophobicContact CG2-CZ 4.32Å; I97-F397 HydrophobicContact CD1-CB 4.21Å; Y214-F397 PolarHBondContact OH-O 3.2Å; L394-F397 HydrophobicContact CB-CD2 4.43Å; L394-F397 HydrophobicContact CD2-CD2 3.99Å; L394-F397 HydrophobicContact CD2-CE2 4.05Å; L394-F397 WeakPolarHBondContact O-CB 3.39Å; L394-F397 WeakPolarHBondContact O-CD2 3.34Å; L394-F397 PolarHBondContact O-N 3.45Å; L395-F397 PolarHBondContact O-N 3.46Å; L395-F397 VanDerWaalsContact O-N 3.16Å; F397-P401 WeakPolarHBondContact O-CD 3.47Å; F397-P401 WeakPolarHBondContact O-CG 3.43Å; F397-Y463 AromaticContact CE2-CD2 3.69Å; F397-Y463 HydrophobicContact CE2-CD2 3.69Å; F397-Y463 AromaticContact CE2-CE2 3.43Å; F397-Y463 HydrophobicContact CE2-CE2 3.43Å; F397-Y463 VanDerWaalsContact CE2-CE2 3.43Å; F397-Y463 AromaticContact CZ-CD2 3.46Å; F397-Y463 HydrophobicContact CZ-CD2 3.46Å; F397-Y463 VanDerWaalsContact CZ-CD2 3.46Å; F397-Y463 AromaticContact CZ-CE2 3.43Å; F397-Y463 HydrophobicContact CZ-CE2 3.43Å; F397-Y463 VanDerWaalsContact CZ-CE2 3.43Å; F397-Y463 HydrophobicContact CZ-CG 4.34Å; F397-L466 HydrophobicContact CD1-CD2 3.94Å; F397-L466 HydrophobicContact CD1-CG 4.18Å; F397-L466 HydrophobicContact CE1-CB 4.07Å; F397-L466 HydrophobicContact CE1-CD2 3.55Å; F397-L466 HydrophobicContact CE1-CG 3.69Å; F397-L466 HydrophobicContact CZ-CD2 4.11Å; F397-T467 WeakPolarHBondContact CE1-OG1 3.25Å; F397-L470 HydrophobicContact CD1-CD1 3.75Å; F397-L470 HydrophobicContact CE1-CD1 4.43Å
398	A	92.9	Very high	90.2	Very high	0 Å²	0	7.9 Å²	7.9	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-85.3	-41	171.1	0	0	0	0	0	112.6	I97 P210 I213 Y214 L395 P396 I402	I97-A398 HydrophobicContact CD1-CB 4.17Å; P210-A398 HydrophobicContact CB-CB 3.74Å; P210-A398 WeakPolarHBondContact O-CB 3.14Å; I213-A398 HydrophobicContact CB-CB 4.24Å; I213-A398 HydrophobicContact CD1-CB 3.94Å; Y214-A398 HydrophobicContact CD2-CB 4.28Å; Y214-A398 HydrophobicContact CE2-CB 3.69Å; L395-A398 PolarHBondContact O-N 3.13Å; P396-A398 VanDerWaalsContact C-N 3.35Å; P396-A398 PolarHBondContact O-N 3.22Å; A398-I402 WeakPolarHBondContact O-CG2 3.49Å
399	V	93.4	Very high	90.1	Very high	1 Å²	1	10.4 Å²	10.4	1%	0.006	6%	0.061	C	C	.	.	H	α-helix	trans	-73.2	-46	-173.6	173	0	0	0	0	112.2	I213 L395 P396 I402 L403 I428 V432	I213-V399 HydrophobicContact CD1-CG2 3.73Å; L395-V399 HydrophobicContact CD1-CG2 3.44Å; L395-V399 VanDerWaalsContact CD1-CG2 3.44Å; L395-V399 HydrophobicContact CG-CG2 3.84Å; L395-V399 WeakPolarHBondContact O-CB 3.21Å; L395-V399 WeakPolarHBondContact O-CG2 3.43Å; L395-V399 PolarHBondContact O-N 3.46Å; P396-V399 PolarHBondContact O-N 3.46Å; V399-I402 WeakPolarHBondContact O-CG2 3.37Å; V399-I402 PolarHBondContact O-N 3.31Å; V399-L403 HydrophobicContact CG1-CD1 3.52Å; V399-L403 HydrophobicContact CG1-CG 3.9Å; V399-L403 VanDerWaalsContact O-CG 3.25Å; V399-L403 WeakPolarHBondContact O-CG 3.24Å; V399-L403 PolarHBondContact O-N 3.36Å; V399-I428 HydrophobicContact CG1-CG2 3.96Å; V399-V432 HydrophobicContact CG1-CG2 4.44Å
400	L	93.4	Very high	90.1	Very high	0 Å²	0	10.4 Å²	10.4	0%	0	6%	0.064	C	C	.	.	H	α-helix	trans	-62.9	-43.3	-175.2	-62.7	172.1	0	0	0	113	P396 I402 L403 T404 M429 T467 L470 A471	P396-L400 HydrophobicContact CB-CD1 3.91Å; P396-L400 HydrophobicContact CB-CG 4.32Å; P396-L400 VanDerWaalsContact O-CB 3.23Å; P396-L400 WeakPolarHBondContact O-CB 3.42Å; P396-L400 WeakPolarHBondContact O-CG 3.48Å; P396-L400 PolarHBondContact O-N 2.94Å; L400-I402 PolarHBondContact O-N 2.93Å; L400-L403 PolarHBondContact O-N 3.43Å; L400-T404 WeakPolarHBondContact O-CB 3.36Å; L400-T404 PolarHBondContact O-N 3.02Å; L400-T404 PolarHBondContact O-OG1 2.97Å; L400-M429 HydrophobicContact CD2-CB 4.29Å; L400-M429 HydrophobicContact CD2-CG 3.66Å; L400-M429 HydrophobicContact CD2-SD 4.47Å; L400-T467 HydrophobicContact CD1-CG2 4.14Å; L400-L470 HydrophobicContact CB-CB 3.87Å; L400-L470 HydrophobicContact CD1-CB 3.78Å; L400-L470 HydrophobicContact CG-CB 4.49Å; L400-A471 HydrophobicContact CD1-CB 4.31Å
401	P	93.6	Very high	90	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-60.1	-43.7	173	-28	38.7	0	0	0	113.5	L77 Y85 L93 F397 T404 F405 L470	L77-P401 HydrophobicContact CD1-CB 4.15Å; Y85-P401 HydrophobicContact CE2-CB 4.25Å; Y85-P401 HydrophobicContact CE2-CG 4.27Å; L93-P401 HydrophobicContact CD2-CG 4Å; F397-P401 WeakPolarHBondContact O-CD 3.47Å; F397-P401 WeakPolarHBondContact O-CG 3.43Å; P401-T404 WeakPolarHBondContact O-CB 3.46Å; P401-T404 PolarHBondContact O-N 2.84Å; P401-F405 HydrophobicContact CB-CD2 4.27Å; P401-F405 HydrophobicContact CB-CE2 4.03Å; P401-F405 WeakPolarHBondContact O-CD2 3.45Å; P401-F405 PolarHBondContact O-N 2.98Å; P401-L470 HydrophobicContact CG-CD2 4.41Å
402	I	93.4	Very high	89.8	Confident	0 Å²	0	9.2 Å²	9.2	0%	0	6%	0.058	C	C	.	.	H	α-helix	trans	-68.6	-38.4	-178.3	-169.7	61.5	0	0	0	112.2	L65 A66 L69 L77 I213 A398 V399 L400 T404 T406	L65-I402 HydrophobicContact CB-CG1 3.91Å; A66-I402 HydrophobicContact CB-CD1 4.4Å; A66-I402 HydrophobicContact CB-CG1 4.38Å; L69-I402 HydrophobicContact CB-CD1 3.71Å; L69-I402 HydrophobicContact CD2-CD1 3.55Å; L69-I402 HydrophobicContact CG-CD1 4.21Å; L77-I402 HydrophobicContact CD1-CB 4.31Å; L77-I402 HydrophobicContact CD1-CD1 4.13Å; L77-I402 HydrophobicContact CD2-CB 4.07Å; I213-I402 HydrophobicContact CG2-CB 4.32Å; I213-I402 HydrophobicContact CG2-CG2 4.04Å; A398-I402 WeakPolarHBondContact O-CG2 3.49Å; V399-I402 WeakPolarHBondContact O-CG2 3.37Å; V399-I402 PolarHBondContact O-N 3.31Å; L400-I402 PolarHBondContact O-N 2.93Å; I402-T404 VanDerWaalsContact C-N 3.32Å; I402-T404 PolarHBondContact O-N 3.44Å; I402-T406 HydrophobicContact CD1-CG2 3.68Å; I402-T406 HydrophobicContact CG1-CG2 4.13Å; I402-T406 WeakPolarHBondContact O-CB 3.45Å; I402-T406 VanDerWaalsContact O-CG2 3.3Å; I402-T406 WeakPolarHBondContact O-CG2 3.43Å; I402-T406 PolarHBondContact O-N 2.82Å; I402-T406 PolarHBondContact O-OG1 3.41Å
403	L	92.1	Very high	89.6	Confident	0 Å²	0	15.1 Å²	15.1	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-65.2	-37.4	173.9	-59.8	177	0	0	0	111.8	L65 V399 L400 S407 T425 I428 M429	L65-L403 HydrophobicContact CD1-CD2 3.77Å; V399-L403 HydrophobicContact CG1-CD1 3.52Å; V399-L403 HydrophobicContact CG1-CG 3.9Å; V399-L403 VanDerWaalsContact O-CG 3.25Å; V399-L403 WeakPolarHBondContact O-CG 3.24Å; V399-L403 PolarHBondContact O-N 3.36Å; L400-L403 PolarHBondContact O-N 3.43Å; L403-S407 VanDerWaalsContact O-CB 3.28Å; L403-S407 WeakPolarHBondContact O-CB 3.42Å; L403-S407 PolarHBondContact O-N 3.32Å; L403-S407 PolarHBondContact O-OG 3.29Å; L403-T425 HydrophobicContact CD2-CG2 3.47Å; L403-T425 VanDerWaalsContact CD2-CG2 3.47Å; L403-I428 HydrophobicContact CD1-CB 4.3Å; L403-I428 HydrophobicContact CD1-CG2 4.03Å; L403-M429 HydrophobicContact CD1-CB 3.99Å
404	T	90.8	Very high	89.3	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-62.2	-63.6	175.6	-58	0	0	0	0	110.4	L400 P401 I402 T406 S407 M408 C474 A477 F491	L400-T404 WeakPolarHBondContact O-CB 3.36Å; L400-T404 PolarHBondContact O-N 3.02Å; L400-T404 PolarHBondContact O-OG1 2.97Å; P401-T404 WeakPolarHBondContact O-CB 3.46Å; P401-T404 PolarHBondContact O-N 2.84Å; I402-T404 VanDerWaalsContact C-N 3.32Å; I402-T404 PolarHBondContact O-N 3.44Å; T404-T406 PolarHBondContact O-N 2.83Å; T404-S407 PolarHBondContact O-N 3.23Å; T404-M408 HydrophobicContact CG2-SD 3.88Å; T404-M408 WeakPolarHBondContact O-CG 3.37Å; T404-M408 PolarHBondContact O-N 3.03Å; T404-C474 VanDerWaalsContact OG1-CA 3.22Å; T404-C474 WeakPolarHBondContact OG1-CA 3.5Å; T404-C474 WeakPolarHBondContact OG1-CB 3.29Å; T404-C474 PolarHBondContact OG1-N 3.38Å; T404-A477 HydrophobicContact CG2-CB 3.85Å; T404-F491 HydrophobicContact CG2-CE1 3.81Å; T404-F491 HydrophobicContact CG2-CZ 3.93Å
405	F	91	Very high	88.9	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-66.5	-36.2	-172.4	-63.7	-53.8	0	0	0	113.1	L69 L77 V80 Y84 Y85 P401 S407 M408 V411 M412 F491	L69-F405 HydrophobicContact CD1-CB 4.05Å; L69-F405 HydrophobicContact CD2-CB 4.45Å; L77-F405 HydrophobicContact CD1-CD2 3.95Å; V80-F405 HydrophobicContact CG1-CB 4.26Å; V80-F405 HydrophobicContact CG1-CD1 3.78Å; V80-F405 HydrophobicContact CG1-CD2 3.67Å; V80-F405 HydrophobicContact CG1-CE1 4.02Å; V80-F405 HydrophobicContact CG1-CE2 3.91Å; V80-F405 HydrophobicContact CG1-CG 3.62Å; V80-F405 HydrophobicContact CG1-CZ 4.08Å; Y84-F405 HydrophobicContact CD1-CE1 4.3Å; Y84-F405 HydrophobicContact CD2-CE1 4.01Å; Y84-F405 AromaticContact CG-CE1 3.7Å; Y84-F405 HydrophobicContact CG-CE1 3.7Å; Y84-F405 HydrophobicContact CG-CZ 4.34Å; Y85-F405 HydrophobicContact CD2-CZ 4.19Å; Y85-F405 AromaticContact CE2-CE2 3.8Å; Y85-F405 HydrophobicContact CE2-CE2 3.8Å; Y85-F405 AromaticContact CE2-CZ 3.66Å; Y85-F405 HydrophobicContact CE2-CZ 3.66Å; P401-F405 HydrophobicContact CB-CD2 4.27Å; P401-F405 HydrophobicContact CB-CE2 4.03Å; P401-F405 WeakPolarHBondContact O-CD2 3.45Å; P401-F405 PolarHBondContact O-N 2.98Å; F405-S407 PolarHBondContact O-N 3.47Å; F405-M408 HydrophobicContact CD1-SD 3.67Å; F405-M408 HydrophobicContact CE1-SD 4.16Å; F405-M408 PolarHBondContact O-N 3.29Å; F405-V411 HydrophobicContact CB-CG1 4.42Å; F405-V411 HydrophobicContact CD1-CG2 4.21Å; F405-M412 WeakPolarHBondContact O-CG 3.48Å; F405-F491 HydrophobicContact CE1-CE2 4.43Å; F405-F491 HydrophobicContact CE1-CZ 4.03Å
406	T	90.6	Very high	88.6	Confident	0 Å²	0	23 Å²	23	0%	0	13%	0.125	C	C	.	.	H	α-helix	trans	-68.6	-15.9	175.8	59.1	0	0	0	0	114.1	L65 L69 I402 T404 M412 N417	L65-T406 HydrophobicContact CB-CG2 4.03Å; L65-T406 HydrophobicContact CD2-CG2 4.18Å; L65-T406 WeakPolarHBondContact O-CG2 3.29Å; L69-T406 HydrophobicContact CB-CG2 4.2Å; I402-T406 HydrophobicContact CD1-CG2 3.68Å; I402-T406 HydrophobicContact CG1-CG2 4.13Å; I402-T406 WeakPolarHBondContact O-CB 3.45Å; I402-T406 VanDerWaalsContact O-CG2 3.3Å; I402-T406 WeakPolarHBondContact O-CG2 3.43Å; I402-T406 PolarHBondContact O-N 2.82Å; I402-T406 PolarHBondContact O-OG1 3.41Å; T404-T406 PolarHBondContact O-N 2.83Å; T406-M412 HydrophobicContact CG2-CE 3.74Å; T406-M412 HydrophobicContact CG2-SD 4.33Å; T406-N417 VanDerWaalsContact O-CG 3.23Å; T406-N417 PolarHBondContact O-N 3.12Å; T406-N417 VanDerWaalsContact O-N 3.15Å; T406-N417 PolarHBondContact O-ND2 3.21Å; T406-N417 PolarHBondContact OG1-ND2 3.23Å; T406-N417 VanDerWaalsContact OG1-ND2 3.09Å
407	S	88.2	Confident	88.2	Confident	0 Å²	0	23.3 Å²	23.3	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-96.4	-8.6	177.7	-60.5	0	0	0	0	114	L403 T404 F405 P409 N417 K422 H478	L403-S407 VanDerWaalsContact O-CB 3.28Å; L403-S407 WeakPolarHBondContact O-CB 3.42Å; L403-S407 PolarHBondContact O-N 3.32Å; L403-S407 PolarHBondContact O-OG 3.29Å; T404-S407 PolarHBondContact O-N 3.23Å; F405-S407 PolarHBondContact O-N 3.47Å; S407-P409 WeakPolarHBondContact O-CD 3.39Å; S407-N417 PolarHBondContact OG-ND2 3.39Å; S407-K422 WeakPolarHBondContact O-CE 3.25Å; S407-K422 PolarHBondContact O-NZ 2.91Å; S407-H478 PolarHBondContact OG-CD2 3.04Å; S407-H478 PolarHBondContact OG-NE2 3.28Å
408	M	85.4	Confident	87.7	Confident	9 Å²	9	25.5 Å²	25.5	4%	0.044	15%	0.149	C	C	.	.			trans	-88.4	118.4	-179.3	-71.3	169.9	67.3	0	0	112	Y84 T404 F405 A410 V411 M412 A477 F491	Y84-M408 HydrophobicContact CD1-CE 4.16Å; Y84-M408 HydrophobicContact CE1-CE 3.97Å; T404-M408 HydrophobicContact CG2-SD 3.88Å; T404-M408 WeakPolarHBondContact O-CG 3.37Å; T404-M408 PolarHBondContact O-N 3.03Å; F405-M408 HydrophobicContact CD1-SD 3.67Å; F405-M408 HydrophobicContact CE1-SD 4.16Å; F405-M408 PolarHBondContact O-N 3.29Å; M408-A410 VanDerWaalsContact C-N 3.26Å; M408-A410 PolarHBondContact O-N 3.47Å; M408-V411 HydrophobicContact CB-CB 4.33Å; M408-V411 HydrophobicContact CB-CG2 4.16Å; M408-V411 HydrophobicContact CE-CG2 4.17Å; M408-V411 PolarHBondContact O-N 3.43Å; M408-V411 HydrophobicContact SD-CG2 4.49Å; M408-M412 PolarHBondContact O-N 2.93Å; M408-A477 HydrophobicContact CG-CB 3.6Å; M408-A477 HydrophobicContact SD-CB 4.31Å; M408-F491 HydrophobicContact CE-CD1 3.82Å; M408-F491 HydrophobicContact CE-CE1 3.81Å; M408-F491 HydrophobicContact CE-CG 4.49Å; M408-F491 HydrophobicContact CE-CZ 4.47Å; M408-F491 WeakPolarHBondContact CE-O 3.37Å; M408-F491 HydrophobicContact SD-CD1 4.19Å; M408-F491 HydrophobicContact SD-CE1 3.6Å; M408-F491 HydrophobicContact SD-CZ 4.21Å
409	P	82.9	Confident	87.4	Confident	83 Å²	83	36.6 Å²	36.6	54%	0.539	19%	0.191	S	C	.	.	H	α-helix	trans	-61.6	-31.3	175.1	-23.6	35.2	0	0	0	113.6	S407 V411 Q413	S407-P409 WeakPolarHBondContact O-CD 3.39Å; P409-V411 PolarHBondContact O-N 2.83Å; P409-Q413 WeakPolarHBondContact O-CA 3.11Å; P409-Q413 PolarHBondContact O-N 3.2Å
410	A	82.6	Confident	87.1	Confident	31 Å²	31	43.8 Å²	43.8	26%	0.256	23%	0.226	S	C	.	.	H	α-helix	trans	-62.6	-29.4	177.4	0	0	0	0	0	113.4	M408 Q413	M408-A410 VanDerWaalsContact C-N 3.26Å; M408-A410 PolarHBondContact O-N 3.47Å; A410-Q413 PolarHBondContact O-NE2 3Å; A410-Q413 VanDerWaalsContact O-NE2 3.17Å
411	V	85.1	Confident	86.7	Confident	15 Å²	15	45 Å²	45	9%	0.091	24%	0.235	C	C	.	.	H	α-helix	trans	-93.3	-48.5	-179.9	179.5	0	0	0	0	111	L69 T73 Y84 F405 M408 P409	L69-V411 HydrophobicContact CD1-CG1 3.73Å; T73-V411 HydrophobicContact CG2-CG1 3.57Å; Y84-V411 HydrophobicContact CE1-CG2 4.29Å; Y84-V411 HydrophobicContact CE2-CG2 3.84Å; F405-V411 HydrophobicContact CB-CG1 4.42Å; F405-V411 HydrophobicContact CD1-CG2 4.21Å; M408-V411 HydrophobicContact CB-CB 4.33Å; M408-V411 HydrophobicContact CB-CG2 4.16Å; M408-V411 HydrophobicContact CE-CG2 4.17Å; M408-V411 PolarHBondContact O-N 3.43Å; M408-V411 HydrophobicContact SD-CG2 4.49Å; P409-V411 PolarHBondContact O-N 2.83Å
412	M	85.3	Confident	86.3	Confident	0 Å²	0	47.2 Å²	47.2	0%	0	25%	0.245	C	C	.	.	H	α-helix	trans	-93.5	-6.1	-171.7	-60.5	-70.2	-87.5	0	0	114.2	R68 L69 V72 F405 T406 M408 E414 F415 A416	R68-M412 HydrophobicContact CB-CE 4.45Å; R68-M412 HydrophobicContact CG-CE 3.71Å; L69-M412 HydrophobicContact CD1-SD 3.69Å; V72-M412 HydrophobicContact CB-SD 4.5Å; F405-M412 WeakPolarHBondContact O-CG 3.48Å; T406-M412 HydrophobicContact CG2-CE 3.74Å; T406-M412 HydrophobicContact CG2-SD 4.33Å; M408-M412 PolarHBondContact O-N 2.93Å; M412-E414 PolarHBondContact O-N 3.37Å; M412-F415 CarbonylContact O-C 3.56Å; M412-F415 WeakPolarHBondContact O-CA 3.47Å; M412-F415 WeakPolarHBondContact O-CB 3.46Å; M412-F415 PolarHBondContact O-N 2.91Å; M412-A416 HydrophobicContact CB-CB 4.19Å
413	Q	83.3	Confident	86	Confident	127 Å²	127	50.3 Å²	50.3	59%	0.593	27%	0.27	S	S	*	.	G	3₁₀ helix	trans	52.7	-135.4	-177.2	-58.1	-63.2	-33.6	0	0	111.1	P409 A410 F415 A416	P409-Q413 WeakPolarHBondContact O-CA 3.11Å; P409-Q413 PolarHBondContact O-N 3.2Å; A410-Q413 PolarHBondContact O-NE2 3Å; A410-Q413 VanDerWaalsContact O-NE2 3.17Å; Q413-F415 PolarHBondContact O-N 3.05Å; Q413-A416 PolarHBondContact O-N 3.04Å
414	E	81.3	Confident	85.9	Confident	134 Å²	134	53.8 Å²	53.8	63%	0.626	29%	0.288	S	S	*	.	G	3₁₀ helix	trans	-62	-19.8	175.3	-62.2	-178.5	-171	0	0	113.4	R230 M412 A416	R230-E414 IonicContact CZ-OE1 3.53Å; R230-E414 IonicContact CZ-OE2 2.77Å; R230-E414 VanDerWaalsContact CZ-OE2 3.32Å; R230-E414 IonicContact NH1-OE1 2.67Å; R230-E414 PolarHBondContact NH1-OE1 2.84Å; R230-E414 IonicContact NH1-OE2 3.5Å; R230-E414 PolarHBondContact NH1-OE2 3.16Å; R230-E414 IonicContact NH2-OE1 3.83Å; R230-E414 PolarHBondContact NH2-OE1 2.96Å; R230-E414 IonicContact NH2-OE2 3.44Å; M412-E414 PolarHBondContact O-N 3.37Å; E414-A416 VanDerWaalsContact C-N 3.26Å; E414-A416 PolarHBondContact O-N 3.02Å
415	F	84.4	Confident	85.7	Confident	54 Å²	54	53.9 Å²	53.9	24%	0.237	29%	0.288	C	S	.	.	G	3₁₀ helix	trans	-87.3	26.4	175.9	-59.1	-82.4	0	0	0	113	R68 V72 V233 R234 M412 Q413	R68-F415 VanDerWaalsContact CZ-O 3.31Å; R68-F415 PolarHBondContact NE-O 2.96Å; R68-F415 PolarHBondContact NH2-O 2.75Å; V72-F415 HydrophobicContact CG1-CB 4.31Å; V72-F415 HydrophobicContact CG1-CD2 4.22Å; V72-F415 HydrophobicContact CG2-CB 3.84Å; V72-F415 HydrophobicContact CG2-CD2 4.11Å; V72-F415 HydrophobicContact CG2-CG 4.01Å; V233-F415 HydrophobicContact CB-CE2 4.24Å; V233-F415 HydrophobicContact CB-CZ 4Å; V233-F415 HydrophobicContact CG1-CD2 4.16Å; V233-F415 HydrophobicContact CG1-CE1 4.11Å; V233-F415 HydrophobicContact CG1-CE2 3.6Å; V233-F415 HydrophobicContact CG1-CZ 3.57Å; R234-F415 HydrophobicContact CB-CE1 4.49Å; M412-F415 CarbonylContact O-C 3.56Å; M412-F415 WeakPolarHBondContact O-CA 3.47Å; M412-F415 WeakPolarHBondContact O-CB 3.46Å; M412-F415 PolarHBondContact O-N 2.91Å; Q413-F415 PolarHBondContact O-N 3.05Å
416	A	83.8	Confident	85.5	Confident	26 Å²	26	56.1 Å²	56.1	22%	0.215	30%	0.304	C	S	.	.	S	Bend	trans	-68.2	160.7	172.5	0	0	0	0	0	113.4	R68 M412 Q413 E414 G418	R68-A416 PolarHBondContact NH2-O 3.35Å; M412-A416 HydrophobicContact CB-CB 4.19Å; Q413-A416 PolarHBondContact O-N 3.04Å; E414-A416 VanDerWaalsContact C-N 3.26Å; E414-A416 PolarHBondContact O-N 3.02Å; A416-G418 PolarHBondContact O-N 2.76Å
417	N	84	Confident	85.5	Confident	8 Å²	8	60.3 Å²	60.3	4%	0.043	33%	0.332	C	S	.	.	P	Polyproline II helix	trans	-65.6	122	175.1	-75.1	-21.9	0	0	0	112.5	R68 T406 S407 S421 K422	R68-N417 PolarHBondContact NH1-OD1 3.41Å; T406-N417 VanDerWaalsContact O-CG 3.23Å; T406-N417 PolarHBondContact O-N 3.12Å; T406-N417 VanDerWaalsContact O-N 3.15Å; T406-N417 PolarHBondContact O-ND2 3.21Å; T406-N417 PolarHBondContact OG1-ND2 3.23Å; T406-N417 VanDerWaalsContact OG1-ND2 3.09Å; S407-N417 PolarHBondContact OG-ND2 3.39Å; N417-S421 PolarHBondContact OD1-OG 2.96Å; N417-K422 HydrophobicContact CB-CG 3.95Å; N417-K422 VanDerWaalsContact O-CE 3.23Å; N417-K422 WeakPolarHBondContact O-CE 3.45Å
418	G	84.8	Confident	85.6	Confident	47 Å²	47	60.8 Å²	60.8	49%	0.485	34%	0.335	S	S	.	.	P	Polyproline II helix	trans	-70.5	168	171.3	0	0	0	0	0	113.1	A416 M420 S421 K422	A416-G418 PolarHBondContact O-N 2.76Å; G418-M420 PolarHBondContact O-N 3.37Å; G418-S421 CarbonylContact O-C 3.59Å; G418-S421 WeakPolarHBondContact O-CA 3.43Å; G418-S421 WeakPolarHBondContact O-CB 3.45Å; G418-S421 PolarHBondContact O-N 3.46Å; G418-K422 PolarHBondContact O-N 2.81Å
419	R	85.2	Confident	85.8	Confident	234 Å²	234	61.2 Å²	61.2	88%	0.883	34%	0.337	S	S	*	.	H	α-helix	trans	-51.4	-47	-170.6	-65.5	-177.4	-178.1	172.8	0.6	114.4	S421 K422 A423	R419-S421 PolarHBondContact O-N 2.85Å; R419-K422 PolarHBondContact O-N 3.07Å; R419-A423 PolarHBondContact O-N 2.95Å
420	M	87.1	Confident	86.1	Confident	151 Å²	151	60.1 Å²	60.1	74%	0.744	34%	0.335	S	S	*	.	H	α-helix	trans	-63.1	-41.4	177.1	-174.1	178.4	77.5	0	0	112	G418 K422 A423 I424	G418-M420 PolarHBondContact O-N 3.37Å; M420-K422 VanDerWaalsContact C-N 3.34Å; M420-K422 PolarHBondContact O-N 2.76Å; M420-A423 PolarHBondContact O-N 3.46Å; M420-I424 HydrophobicContact CG-CD1 4.3Å; M420-I424 WeakPolarHBondContact O-CG1 3.46Å; M420-I424 PolarHBondContact O-N 2.91Å
421	S	85.2	Confident	86.4	Confident	25 Å²	25	62.7 Å²	62.7	18%	0.175	34%	0.344	C	S	.	.	H	α-helix	trans	-64.4	-39.2	175.3	-165.7	0	0	0	0	111.3	N417 G418 R419 I424 T425	N417-S421 PolarHBondContact OD1-OG 2.96Å; G418-S421 CarbonylContact O-C 3.59Å; G418-S421 WeakPolarHBondContact O-CA 3.43Å; G418-S421 WeakPolarHBondContact O-CB 3.45Å; G418-S421 PolarHBondContact O-N 3.46Å; R419-S421 PolarHBondContact O-N 2.85Å; S421-I424 PolarHBondContact O-N 3.14Å; S421-T425 WeakPolarHBondContact O-CG2 3.42Å; S421-T425 PolarHBondContact O-N 3.05Å; S421-T425 PolarHBondContact O-OG1 3.01Å
422	K	84.9	Confident	86.5	Confident	48 Å²	48	62.2 Å²	62.2	21%	0.209	34%	0.341	C	S	.	.	H	α-helix	trans	-65	-36.2	175	-68.6	-163.1	175.1	-156.4	0	112.9	S407 N417 G418 R419 M420 T425 S426 A477	S407-K422 WeakPolarHBondContact O-CE 3.25Å; S407-K422 PolarHBondContact O-NZ 2.91Å; N417-K422 HydrophobicContact CB-CG 3.95Å; N417-K422 VanDerWaalsContact O-CE 3.23Å; N417-K422 WeakPolarHBondContact O-CE 3.45Å; G418-K422 PolarHBondContact O-N 2.81Å; R419-K422 PolarHBondContact O-N 3.07Å; M420-K422 VanDerWaalsContact C-N 3.34Å; M420-K422 PolarHBondContact O-N 2.76Å; K422-T425 WeakPolarHBondContact CA-OG1 3.41Å; K422-T425 PolarHBondContact O-OG1 3.04Å; K422-T425 VanDerWaalsContact O-OG1 3.13Å; K422-S426 VanDerWaalsContact O-CB 3.24Å; K422-S426 WeakPolarHBondContact O-CB 3.48Å; K422-S426 PolarHBondContact O-N 3.31Å; K422-A477 PolarHBondContact NZ-O 3.42Å; K422-A477 VanDerWaalsContact NZ-O 3.09Å
423	A	88.5	Confident	86.6	Confident	65 Å²	65	63.8 Å²	63.8	54%	0.537	35%	0.352	S	S	.	.	H	α-helix	trans	-64.3	-44.8	173.6	0	0	0	0	0	111.4	R419 M420 S426 C427	R419-A423 PolarHBondContact O-N 2.95Å; M420-A423 PolarHBondContact O-N 3.46Å; A423-S426 PolarHBondContact O-N 3.07Å; A423-C427 PolarHBondContact O-N 3.04Å
424	I	88.8	Confident	86.9	Confident	72 Å²	72	60.5 Å²	60.5	37%	0.369	35%	0.346	S	S	.	.	H	α-helix	trans	-62.4	-50.4	175.6	-65.3	165.2	0	0	0	110.7	L61 M420 S421 S426 C427 I428	L61-I424 HydrophobicContact CD1-CG2 4.16Å; M420-I424 HydrophobicContact CG-CD1 4.3Å; M420-I424 WeakPolarHBondContact O-CG1 3.46Å; M420-I424 PolarHBondContact O-N 2.91Å; S421-I424 PolarHBondContact O-N 3.14Å; I424-S426 VanDerWaalsContact C-N 3.27Å; I424-S426 PolarHBondContact O-N 3.07Å; I424-C427 WeakPolarHBondContact O-CB 3.23Å; I424-C427 PolarHBondContact O-N 2.92Å; I424-C427 VanDerWaalsContact O-N 3.09Å; I424-I428 HydrophobicContact CG2-CD1 3.98Å; I424-I428 WeakPolarHBondContact O-CG1 3.43Å; I424-I428 PolarHBondContact O-N 3.43Å
425	T	86.7	Confident	87	Confident	2 Å²	2	55.7 Å²	55.7	1%	0.012	32%	0.324	C	S	.	.	H	α-helix	trans	-62.2	-34.2	178.4	56.9	0	0	0	0	112.3	L65 L403 S421 K422 I428 M429 H478	L65-T425 HydrophobicContact CD1-CG2 3.75Å; L403-T425 HydrophobicContact CD2-CG2 3.47Å; L403-T425 VanDerWaalsContact CD2-CG2 3.47Å; S421-T425 WeakPolarHBondContact O-CG2 3.42Å; S421-T425 PolarHBondContact O-N 3.05Å; S421-T425 PolarHBondContact O-OG1 3.01Å; K422-T425 WeakPolarHBondContact CA-OG1 3.41Å; K422-T425 PolarHBondContact O-OG1 3.04Å; K422-T425 VanDerWaalsContact O-OG1 3.13Å; T425-I428 PolarHBondContact O-N 3.25Å; T425-M429 WeakPolarHBondContact O-CB 3.02Å; T425-M429 PolarHBondContact O-N 3.16Å; T425-H478 PolarHBondContact OG1-CE1 2.94Å; T425-H478 VanDerWaalsContact OG1-CE1 3.26Å; T425-H478 PolarHBondContact OG1-NE2 3.12Å; T425-H478 VanDerWaalsContact OG1-NE2 3.1Å
426	S	88.1	Confident	87.1	Confident	48 Å²	48	53.3 Å²	53.3	34%	0.336	31%	0.314	S	S	.	.	H	α-helix	trans	-68.8	-34.3	174.7	-159.8	0	0	0	0	112.9	K422 A423 I424 A430 H478	K422-S426 VanDerWaalsContact O-CB 3.24Å; K422-S426 WeakPolarHBondContact O-CB 3.48Å; K422-S426 PolarHBondContact O-N 3.31Å; A423-S426 PolarHBondContact O-N 3.07Å; I424-S426 VanDerWaalsContact C-N 3.27Å; I424-S426 PolarHBondContact O-N 3.07Å; S426-A430 WeakPolarHBondContact O-CB 3.05Å; S426-A430 PolarHBondContact O-N 3.47Å; S426-H478 PolarHBondContact N-CE1 3.2Å
427	C	90.7	Very high	87.1	Confident	87 Å²	87	56.1 Å²	56.1	59%	0.588	33%	0.325	S	S	*	.	H	α-helix	trans	-66.2	-44.9	172.4	-173.4	0	0	0	0	111.1	A423 I424 M429 A430 L431	A423-C427 PolarHBondContact O-N 3.04Å; I424-C427 WeakPolarHBondContact O-CB 3.23Å; I424-C427 PolarHBondContact O-N 2.92Å; I424-C427 VanDerWaalsContact O-N 3.09Å; C427-M429 PolarHBondContact O-N 2.85Å; C427-A430 PolarHBondContact O-N 2.98Å; C427-L431 WeakPolarHBondContact O-CB 3.36Å; C427-L431 PolarHBondContact O-N 3.08Å
428	I	89.2	Confident	87.2	Confident	11 Å²	11	60 Å²	60	6%	0.056	34%	0.34	C	S	.	.	H	α-helix	trans	-59.1	-47.9	175.7	-63.1	171	0	0	0	111	L58 L61 V399 L403 I424 T425 A430 L431 V432	L58-I428 HydrophobicContact CD1-CB 4.21Å; L58-I428 HydrophobicContact CD1-CD1 3.44Å; L58-I428 VanDerWaalsContact CD1-CD1 3.44Å; L58-I428 HydrophobicContact CD1-CG1 3.44Å; L58-I428 VanDerWaalsContact CD1-CG1 3.44Å; L58-I428 HydrophobicContact CD1-CG2 3.77Å; L61-I428 HydrophobicContact CD1-CD1 4.4Å; V399-I428 HydrophobicContact CG1-CG2 3.96Å; L403-I428 HydrophobicContact CD1-CB 4.3Å; L403-I428 HydrophobicContact CD1-CG2 4.03Å; I424-I428 HydrophobicContact CG2-CD1 3.98Å; I424-I428 WeakPolarHBondContact O-CG1 3.43Å; I424-I428 PolarHBondContact O-N 3.43Å; T425-I428 PolarHBondContact O-N 3.25Å; I428-A430 VanDerWaalsContact C-N 3.34Å; I428-A430 PolarHBondContact O-N 3.49Å; I428-L431 PolarHBondContact O-N 3.1Å; I428-V432 HydrophobicContact CG2-CG2 4.25Å; I428-V432 WeakPolarHBondContact O-CB 3.3Å; I428-V432 WeakPolarHBondContact O-CG2 3.22Å; I428-V432 PolarHBondContact O-N 3.4Å
429	M	89.8	Confident	86.9	Confident	18 Å²	18	59.1 Å²	59.1	9%	0.089	32%	0.322	C	S	.	.	H	α-helix	trans	-55.8	-48	175.4	174.3	-178.9	74.2	0	0	111.6	L400 L403 T425 C427 C433 C474	L400-M429 HydrophobicContact CD2-CB 4.29Å; L400-M429 HydrophobicContact CD2-CG 3.66Å; L400-M429 HydrophobicContact CD2-SD 4.47Å; L403-M429 HydrophobicContact CD1-CB 3.99Å; T425-M429 WeakPolarHBondContact O-CB 3.02Å; T425-M429 PolarHBondContact O-N 3.16Å; C427-M429 PolarHBondContact O-N 2.85Å; M429-C433 WeakPolarHBondContact O-CB 3.37Å; M429-C433 PolarHBondContact O-N 3.41Å; M429-C433 PolarHBondContact O-SG 3.48Å; M429-C474 HydrophobicContact SD-CB 3.63Å; M429-C474 VanDerWaalsContact SD-SG 3.62Å
430	A	90.1	Very high	86.7	Confident	59 Å²	59	48.6 Å²	48.6	49%	0.488	28%	0.284	S	S	.	.	H	α-helix	trans	-63.1	-44.4	179.5	0	0	0	0	0	112.1	S426 C427 I428 A434	S426-A430 WeakPolarHBondContact O-CB 3.05Å; S426-A430 PolarHBondContact O-N 3.47Å; C427-A430 PolarHBondContact O-N 2.98Å; I428-A430 VanDerWaalsContact C-N 3.34Å; I428-A430 PolarHBondContact O-N 3.49Å; A430-A434 WeakPolarHBondContact O-CB 3.5Å; A430-A434 PolarHBondContact O-N 3Å
431	L	88.4	Confident	86.4	Confident	86 Å²	86	46.4 Å²	46.4	45%	0.45	27%	0.274	S	S	.	.	H	α-helix	trans	-61.1	-50.9	177.8	179.2	64.6	0	0	0	111.8	L58 C427 I428 C433 A434 I435	L58-L431 HydrophobicContact CD2-CD2 4.4Å; C427-L431 WeakPolarHBondContact O-CB 3.36Å; C427-L431 PolarHBondContact O-N 3.08Å; I428-L431 PolarHBondContact O-N 3.1Å; L431-C433 PolarHBondContact O-N 2.87Å; L431-A434 PolarHBondContact O-N 3.26Å; L431-I435 HydrophobicContact CD1-CD1 3.87Å; L431-I435 HydrophobicContact CD1-CG1 4.32Å; L431-I435 HydrophobicContact CG-CD1 3.92Å; L431-I435 WeakPolarHBondContact O-CG1 3.41Å; L431-I435 PolarHBondContact O-N 2.04Å
432	V	87.6	Confident	86.1	Confident	5 Å²	5	47 Å²	47	3%	0.03	28%	0.279	C	S	.	.	H	α-helix	trans	-62.9	-43.3	-179.2	168.8	0	0	0	0	111	L395 P396 V399 I428 N436	L395-V432 HydrophobicContact CD2-CG2 4.45Å; P396-V432 HydrophobicContact CB-CG1 3.92Å; P396-V432 HydrophobicContact CG-CG1 3.65Å; V399-V432 HydrophobicContact CG1-CG2 4.44Å; I428-V432 HydrophobicContact CG2-CG2 4.25Å; I428-V432 WeakPolarHBondContact O-CB 3.3Å; I428-V432 WeakPolarHBondContact O-CG2 3.22Å; I428-V432 PolarHBondContact O-N 3.4Å; V432-N436 WeakPolarHBondContact O-CB 3.4Å; V432-N436 PolarHBondContact O-N 3.21Å; V432-N436 PolarHBondContact O-ND2 2.89Å
433	C	87.6	Confident	85.6	Confident	33 Å²	33	48.8 Å²	48.8	22%	0.223	29%	0.285	C	S	.	.	H	α-helix	trans	-65.5	-39.5	174.8	-71.5	0	0	0	0	112.7	M429 L431 L437	M429-C433 WeakPolarHBondContact O-CB 3.37Å; M429-C433 PolarHBondContact O-N 3.41Å; M429-C433 PolarHBondContact O-SG 3.48Å; L431-C433 PolarHBondContact O-N 2.87Å; C433-L437 VanDerWaalsContact O-CB 3.26Å; C433-L437 WeakPolarHBondContact O-CB 3.18Å; C433-L437 PolarHBondContact O-N 2.9Å
434	A	88.3	Confident	84.8	Confident	57 Å²	57	47.4 Å²	47.4	47%	0.471	27%	0.268	S	S	.	.	H	α-helix	trans	-66.7	-46.1	179.7	0	0	0	0	0	112.3	A430 L431 N436 L437 Y438	A430-A434 WeakPolarHBondContact O-CB 3.5Å; A430-A434 PolarHBondContact O-N 3Å; L431-A434 PolarHBondContact O-N 3.26Å; A434-N436 VanDerWaalsContact C-N 3.33Å; A434-N436 PolarHBondContact O-N 3.46Å; A434-L437 PolarHBondContact O-N 3.41Å; A434-Y438 VanDerWaalsContact O-CB 3.32Å; A434-Y438 WeakPolarHBondContact O-CB 3.45Å; A434-Y438 PolarHBondContact O-N 3.47Å
435	I	84.2	Confident	84	Confident	33 Å²	33	49 Å²	49	17%	0.169	28%	0.284	C	S	.	.	H	α-helix	trans	-56.8	-48.1	175.7	-73.2	168.6	0	0	0	110.6	V201 L431 Y438 F439	V201-I435 HydrophobicContact CB-CG2 4.38Å; V201-I435 HydrophobicContact CG1-CG2 3.78Å; V201-I435 HydrophobicContact CG2-CG2 3.64Å; L431-I435 HydrophobicContact CD1-CD1 3.87Å; L431-I435 HydrophobicContact CD1-CG1 4.32Å; L431-I435 HydrophobicContact CG-CD1 3.92Å; L431-I435 WeakPolarHBondContact O-CG1 3.41Å; L431-I435 PolarHBondContact O-N 2.04Å; I435-Y438 PolarHBondContact O-N 3.22Å; I435-F439 WeakPolarHBondContact O-CB 3.34Å; I435-F439 PolarHBondContact O-N 2.71Å
436	N	85.4	Confident	83.1	Confident	4 Å²	4	50.7 Å²	50.7	2%	0.021	30%	0.295	C	S	.	.	H	α-helix	trans	-71.8	-36.8	-176.4	-80.1	-80	0	0	0	113	S392 L393 P396 V432 A434 F439 V440 Y463	S392-N436 PolarHBondContact O-OD1 3.12Å; L393-N436 VanDerWaalsContact CA-OD1 3.26Å; L393-N436 WeakPolarHBondContact CA-OD1 3.5Å; L393-N436 PolarHBondContact O-OD1 3.45Å; P396-N436 HydrophobicContact CG-CB 4.16Å; P396-N436 VanDerWaalsContact CG-ND2 3.33Å; P396-N436 WeakPolarHBondContact CG-ND2 3.24Å; V432-N436 WeakPolarHBondContact O-CB 3.4Å; V432-N436 PolarHBondContact O-N 3.21Å; V432-N436 PolarHBondContact O-ND2 2.89Å; A434-N436 VanDerWaalsContact C-N 3.33Å; A434-N436 PolarHBondContact O-N 3.46Å; N436-F439 PolarHBondContact O-N 3.16Å; N436-V440 WeakPolarHBondContact O-CG2 3.07Å; N436-V440 PolarHBondContact O-N 2.93Å; N436-V440 VanDerWaalsContact O-N 3.07Å; N436-Y463 HydrophobicContact CB-CE1 4.49Å; N436-Y463 WeakPolarHBondContact CB-OH 3.27Å; N436-Y463 VanDerWaalsContact CG-OH 3.24Å; N436-Y463 PolarHBondContact OD1-OH 3.23Å
437	L	85.4	Confident	82.2	Confident	86 Å²	86	50 Å²	50	45%	0.45	29%	0.288	S	S	.	.	H	α-helix	trans	-64	-44.4	172.8	-178.9	62.2	0	0	0	111.3	C433 A434 V440 I441 L464	C433-L437 VanDerWaalsContact O-CB 3.26Å; C433-L437 WeakPolarHBondContact O-CB 3.18Å; C433-L437 PolarHBondContact O-N 2.9Å; A434-L437 PolarHBondContact O-N 3.41Å; L437-V440 PolarHBondContact O-N 2.91Å; L437-I441 HydrophobicContact CD1-CD1 3.93Å; L437-I441 HydrophobicContact CD1-CG1 4.42Å; L437-I441 HydrophobicContact CG-CD1 3.87Å; L437-I441 WeakPolarHBondContact O-CB 3.39Å; L437-I441 VanDerWaalsContact O-CG1 3.27Å; L437-I441 WeakPolarHBondContact O-CG1 3.46Å; L437-I441 PolarHBondContact O-N 3.5Å; L437-L464 HydrophobicContact CD1-CD2 4.03Å
438	Y	84.5	Confident	81	Confident	90 Å²	90	50.4 Å²	50.4	35%	0.353	29%	0.289	S	S	.	.	H	α-helix	trans	-59.8	-46.6	175.4	177	-92.9	0	0	0	111.7	Q194 L197 A434 I435 V440 I441 S442	Q194-Y438 PolarHBondContact NE2-OH 2.95Å; Q194-Y438 PolarHBondContact OE1-OH 3.34Å; L197-Y438 HydrophobicContact CD2-CD1 4.06Å; L197-Y438 HydrophobicContact CD2-CE1 3.37Å; L197-Y438 HydrophobicContact CD2-CE2 4.38Å; L197-Y438 HydrophobicContact CG-CE1 4.15Å; A434-Y438 VanDerWaalsContact O-CB 3.32Å; A434-Y438 WeakPolarHBondContact O-CB 3.45Å; A434-Y438 PolarHBondContact O-N 3.47Å; I435-Y438 PolarHBondContact O-N 3.22Å; Y438-V440 PolarHBondContact O-N 3.31Å; Y438-I441 PolarHBondContact O-N 3.37Å; Y438-S442 WeakPolarHBondContact O-CB 3.47Å; Y438-S442 PolarHBondContact O-N 3.43Å
439	F	78.9	Confident	80.2	Confident	27 Å²	27	55.6 Å²	55.6	12%	0.118	31%	0.313	C	S	.	.	H	α-helix	trans	-58	-49.1	178.2	-177	-90.4	0	0	0	111.9	L198 V389 L393 I435 N436 I441 S442 Y443	L198-F439 HydrophobicContact CD2-CD2 3.71Å; L198-F439 HydrophobicContact CD2-CE2 3.59Å; V389-F439 HydrophobicContact CG1-CD2 4.28Å; V389-F439 HydrophobicContact CG1-CE1 4.17Å; V389-F439 HydrophobicContact CG1-CE2 3.29Å; V389-F439 HydrophobicContact CG1-CZ 3.23Å; L393-F439 HydrophobicContact CD1-CD1 3.92Å; L393-F439 HydrophobicContact CD1-CE1 4.35Å; I435-F439 WeakPolarHBondContact O-CB 3.34Å; I435-F439 PolarHBondContact O-N 2.71Å; N436-F439 PolarHBondContact O-N 3.16Å; F439-I441 VanDerWaalsContact C-N 3.34Å; F439-I441 PolarHBondContact O-N 2.91Å; F439-S442 PolarHBondContact O-N 3.31Å; F439-Y443 HydrophobicContact CE1-CG 4.38Å; F439-Y443 HydrophobicContact CZ-CD2 4.18Å; F439-Y443 HydrophobicContact CZ-CG 4.46Å; F439-Y443 VanDerWaalsContact O-CB 3.28Å; F439-Y443 WeakPolarHBondContact O-CB 3.17Å; F439-Y443 PolarHBondContact O-N 3.48Å
440	V	80.4	Confident	79.3	Confident	14 Å²	14	60.1 Å²	60.1	9%	0.085	34%	0.343	C	S	.	.	H	α-helix	trans	-60.1	-42.9	177.9	171.2	0	0	0	0	111.6	L393 N436 L437 Y438 L444 A460 Y463 L464	L393-V440 HydrophobicContact CD1-CG2 4.4Å; N436-V440 WeakPolarHBondContact O-CG2 3.07Å; N436-V440 PolarHBondContact O-N 2.93Å; N436-V440 VanDerWaalsContact O-N 3.07Å; L437-V440 PolarHBondContact O-N 2.91Å; Y438-V440 PolarHBondContact O-N 3.31Å; V440-L444 HydrophobicContact CG1-CD1 3.84Å; V440-L444 WeakPolarHBondContact O-CB 3.5Å; V440-L444 PolarHBondContact O-N 2.9Å; V440-L444 VanDerWaalsContact O-N 3.15Å; V440-A460 HydrophobicContact CG1-CB 3.98Å; V440-Y463 HydrophobicContact CG2-CD1 4.04Å; V440-Y463 HydrophobicContact CG2-CE1 4.01Å; V440-L464 HydrophobicContact CG1-CD1 4.14Å; V440-L464 HydrophobicContact CG1-CG 4.48Å
441	I	82.4	Confident	78.3	Confident	104 Å²	104	61.4 Å²	61.4	53%	0.533	35%	0.354	S	S	.	.	H	α-helix	trans	-67.2	-36.9	178.7	-68.9	168.8	0	0	0	112.1	L437 Y438 F439 P445	L437-I441 HydrophobicContact CD1-CD1 3.93Å; L437-I441 HydrophobicContact CD1-CG1 4.42Å; L437-I441 HydrophobicContact CG-CD1 3.87Å; L437-I441 WeakPolarHBondContact O-CB 3.39Å; L437-I441 VanDerWaalsContact O-CG1 3.27Å; L437-I441 WeakPolarHBondContact O-CG1 3.46Å; L437-I441 PolarHBondContact O-N 3.5Å; Y438-I441 PolarHBondContact O-N 3.37Å; F439-I441 VanDerWaalsContact C-N 3.34Å; F439-I441 PolarHBondContact O-N 2.91Å; I441-P445 WeakPolarHBondContact O-CD 3.3Å; I441-P445 WeakPolarHBondContact O-CG 3.01Å
442	S	77.7	Confident	77.6	Confident	38 Å²	38	64.3 Å²	64.3	27%	0.266	36%	0.36	S	S	.	.	H	α-helix	trans	-76.4	-33.8	178.1	-165.1	0	0	0	0	112.6	Q194 Y438 F439 P445	Q194-S442 PolarHBondContact OE1-OG 2.94Å; Y438-S442 WeakPolarHBondContact O-CB 3.47Å; Y438-S442 PolarHBondContact O-N 3.43Å; F439-S442 PolarHBondContact O-N 3.31Å; S442-P445 WeakPolarHBondContact O-CD 2.98Å
443	Y	74.4	Confident	77.1	Confident	85 Å²	85	68.9 Å²	68.9	33%	0.333	38%	0.38	S	S	.	.	H	α-helix	trans	-76.2	-40.5	-177.2	-169.1	-99.1	0	0	0	113	F439 S446 L447	F439-Y443 HydrophobicContact CE1-CG 4.38Å; F439-Y443 HydrophobicContact CZ-CD2 4.18Å; F439-Y443 HydrophobicContact CZ-CG 4.46Å; F439-Y443 VanDerWaalsContact O-CB 3.28Å; F439-Y443 WeakPolarHBondContact O-CB 3.17Å; F439-Y443 PolarHBondContact O-N 3.48Å; Y443-S446 PolarHBondContact O-N 3.14Å; Y443-S446 PolarHBondContact O-OG 2.98Å; Y443-L447 HydrophobicContact CE1-CD2 3.94Å
444	L	72.4	Confident	76.7	Confident	37 Å²	37	69.6 Å²	69.6	19%	0.194	39%	0.393	C	S	.	.	G	3₁₀ helix	trans	-53.5	-45	-178	-91.2	160.5	0	0	0	114.6	V440 S446 F453 V456 A457 A460	V440-L444 HydrophobicContact CG1-CD1 3.84Å; V440-L444 WeakPolarHBondContact O-CB 3.5Å; V440-L444 PolarHBondContact O-N 2.9Å; V440-L444 VanDerWaalsContact O-N 3.15Å; L444-S446 VanDerWaalsContact C-N 3.3Å; L444-S446 PolarHBondContact O-N 3.38Å; L444-F453 HydrophobicContact CD2-CE2 4.12Å; L444-F453 HydrophobicContact CD2-CZ 4.46Å; L444-V456 HydrophobicContact CD2-CG1 4.37Å; L444-A457 HydrophobicContact CD2-CB 4.31Å; L444-A460 HydrophobicContact CD1-CB 4.23Å
445	P	71.9	Confident	76.4	Confident	106 Å²	106	71.7 Å²	71.7	69%	0.688	40%	0.396	S	S	*	.	G	3₁₀ helix	trans	-72.3	-15.5	177.1	-20.3	33.9	0	0	0	115.3	I441 S442 L447	I441-P445 WeakPolarHBondContact O-CD 3.3Å; I441-P445 WeakPolarHBondContact O-CG 3.01Å; S442-P445 WeakPolarHBondContact O-CD 2.98Å; P445-L447 VanDerWaalsContact C-N 3.34Å
446	S	67.9	Low	76.3	Confident	37 Å²	37	71.8 Å²	71.8	26%	0.259	40%	0.398	S	S	.	.	G	3₁₀ helix	trans	-86	-4.5	-174.6	72.9	0	0	0	0	114.2	Y443 L444	Y443-S446 PolarHBondContact O-N 3.14Å; Y443-S446 PolarHBondContact O-OG 2.98Å; L444-S446 VanDerWaalsContact C-N 3.3Å; L444-S446 PolarHBondContact O-N 3.38Å
447	L	68.5	Low	76.1	Confident	33 Å²	33	72.6 Å²	72.6	17%	0.173	41%	0.405	C	S	.	.			trans	-70.4	126.5	-177.5	-67.4	171.7	0	0	0	112.1	Y443 P445 H449 F453 V456	Y443-L447 HydrophobicContact CE1-CD2 3.94Å; P445-L447 VanDerWaalsContact C-N 3.34Å; L447-H449 VanDerWaalsContact C-N 3.32Å; L447-H449 PolarHBondContact O-N 3.48Å; L447-F453 HydrophobicContact CD1-CD2 4.48Å; L447-V456 HydrophobicContact CD1-CB 3.69Å; L447-V456 HydrophobicContact CD1-CG1 3.85Å; L447-V456 HydrophobicContact CD1-CG2 3.86Å; L447-V456 HydrophobicContact CD2-CG2 4.39Å
448	P	65.2	Low	76.1	Confident	95 Å²	95	74.4 Å²	74.4	62%	0.617	41%	0.414	S	S	*	.	S	Bend	trans	-74.8	-11.9	-170	28	-35.9	0	0	0	115.4
449	H	72.4	Confident	76.2	Confident	121 Å²	121	77 Å²	77	56%	0.56	43%	0.427	S	S	*	.			trans	-139.8	131.9	-175.8	-100	-48.1	0	0	0	113	L447 A451 Y452 F453	L447-H449 VanDerWaalsContact C-N 3.32Å; L447-H449 PolarHBondContact O-N 3.48Å; H449-A451 PolarHBondContact O-N 3.33Å; H449-A451 VanDerWaalsContact O-N 3.16Å; H449-Y452 HydrophobicContact CB-CD2 3.72Å; H449-Y452 HydrophobicContact CB-CE2 4.2Å; H449-Y452 PolarHBondContact O-N 3.3Å; H449-Y452 VanDerWaalsContact O-N 3.15Å; H449-F453 PolarHBondContact O-N 3.4Å
450	P	70.8	Confident	76.5	Confident	112 Å²	112	76.2 Å²	76.2	73%	0.727	43%	0.426	S	S	*	.	H	α-helix	trans	-67.2	-18.1	-176.1	26.9	-35.2	0	0	0	114.2	F453	P450-F453 WeakPolarHBondContact O-CB 3.19Å; P450-F453 PolarHBondContact O-N 3.49Å
451	A	70.1	Confident	76.8	Confident	86 Å²	86	81.3 Å²	81.3	71%	0.711	45%	0.452	S	S	*	.	H	α-helix	trans	-67.4	-38.4	173.7	0	0	0	0	0	112.4	H449 F453	H449-A451 PolarHBondContact O-N 3.33Å; H449-A451 VanDerWaalsContact O-N 3.16Å; A451-F453 VanDerWaalsContact C-N 3.33Å
452	Y	72.8	Confident	77.2	Confident	147 Å²	147	78.5 Å²	78.5	58%	0.576	45%	0.449	S	S	*	.	H	α-helix	trans	-74.9	-26	175.7	-64.5	-77.5	0	0	0	112.1	H449 G454 L455 V456	H449-Y452 HydrophobicContact CB-CD2 3.72Å; H449-Y452 HydrophobicContact CB-CE2 4.2Å; H449-Y452 PolarHBondContact O-N 3.3Å; H449-Y452 VanDerWaalsContact O-N 3.15Å; Y452-G454 VanDerWaalsContact C-N 3.32Å; Y452-G454 PolarHBondContact O-N 3.02Å; Y452-L455 PolarHBondContact O-N 3.17Å; Y452-V456 WeakPolarHBondContact O-CG2 3.38Å; Y452-V456 PolarHBondContact O-N 2.83Å
453	F	78.1	Confident	77.8	Confident	102 Å²	102	78 Å²	78	45%	0.447	44%	0.441	S	S	.	.	H	α-helix	trans	-55.6	-44.2	179	-171.5	-90.7	0	0	0	112.3	L444 L447 H449 P450 A451 L455 A457	L444-F453 HydrophobicContact CD2-CE2 4.12Å; L444-F453 HydrophobicContact CD2-CZ 4.46Å; L447-F453 HydrophobicContact CD1-CD2 4.48Å; H449-F453 PolarHBondContact O-N 3.4Å; P450-F453 WeakPolarHBondContact O-CB 3.19Å; P450-F453 PolarHBondContact O-N 3.49Å; A451-F453 VanDerWaalsContact C-N 3.33Å; F453-L455 PolarHBondContact O-N 2.96Å; F453-A457 WeakPolarHBondContact O-CB 3.02Å; F453-A457 PolarHBondContact O-N 3.33Å
454	G	79.2	Confident	78.6	Confident	48 Å²	48	77 Å²	77	50%	0.495	44%	0.441	S	S	.	.	H	α-helix	trans	-63.3	-40.7	178.9	0	0	0	0	0	113.6	Y452 L458	Y452-G454 VanDerWaalsContact C-N 3.32Å; Y452-G454 PolarHBondContact O-N 3.02Å; G454-L458 PolarHBondContact O-N 2.84Å; G454-L458 VanDerWaalsContact O-N 3.1Å
455	L	81	Confident	79.5	Confident	101 Å²	101	77.2 Å²	77.2	53%	0.529	45%	0.453	S	S	.	.	H	α-helix	trans	-72.5	-45.3	179.1	-178.5	132.1	0	0	0	111.7	Y452 F453 L458 F459	Y452-L455 PolarHBondContact O-N 3.17Å; F453-L455 PolarHBondContact O-N 2.96Å; L455-L458 WeakPolarHBondContact O-CB 3.4Å; L455-L458 PolarHBondContact O-N 3.48Å; L455-F459 HydrophobicContact CD2-CD2 3.92Å; L455-F459 HydrophobicContact CD2-CE2 3.76Å; L455-F459 HydrophobicContact CG-CD2 4.12Å; L455-F459 HydrophobicContact CG-CE2 3.91Å; L455-F459 VanDerWaalsContact O-CD2 3.24Å; L455-F459 WeakPolarHBondContact O-CD2 3.45Å; L455-F459 PolarHBondContact O-N 3.03Å; L455-F459 VanDerWaalsContact O-N 3.09Å
456	V	81.9	Confident	80.5	Confident	35 Å²	35	73 Å²	73	21%	0.212	42%	0.424	C	S	.	.	H	α-helix	trans	-66.9	-36.8	176.6	178.9	0	0	0	0	111.3	L444 L447 Y452 L458 F459 A460	L444-V456 HydrophobicContact CD2-CG1 4.37Å; L447-V456 HydrophobicContact CD1-CB 3.69Å; L447-V456 HydrophobicContact CD1-CG1 3.85Å; L447-V456 HydrophobicContact CD1-CG2 3.86Å; L447-V456 HydrophobicContact CD2-CG2 4.39Å; Y452-V456 WeakPolarHBondContact O-CG2 3.38Å; Y452-V456 PolarHBondContact O-N 2.83Å; V456-L458 PolarHBondContact O-N 2.77Å; V456-F459 PolarHBondContact O-N 2.03Å; V456-A460 VanDerWaalsContact O-CB 3.32Å; V456-A460 WeakPolarHBondContact O-CB 3.16Å; V456-A460 PolarHBondContact O-N 2.86Å
457	A	81.3	Confident	81.5	Confident	21 Å²	21	71.7 Å²	71.7	17%	0.174	42%	0.415	C	S	.	.	H	α-helix	trans	-62.8	-39.4	173.2	0	0	0	0	0	112.2	L444 F453 A460 I461	L444-A457 HydrophobicContact CD2-CB 4.31Å; F453-A457 WeakPolarHBondContact O-CB 3.02Å; F453-A457 PolarHBondContact O-N 3.33Å; A457-A460 PolarHBondContact O-N 3.24Å; A457-I461 WeakPolarHBondContact O-CB 3.48Å; A457-I461 WeakPolarHBondContact O-CD1 3.17Å; A457-I461 VanDerWaalsContact O-CG1 3.23Å; A457-I461 WeakPolarHBondContact O-CG1 3.26Å; A457-I461 PolarHBondContact O-N 3.29Å
458	L	85.8	Confident	82.6	Confident	124 Å²	124	73 Å²	73	65%	0.649	43%	0.431	S	S	*	.	H	α-helix	trans	-60.9	-47	173.8	-173	76.9	0	0	0	111.5	G454 L455 V456 I461 G462	G454-L458 PolarHBondContact O-N 2.84Å; G454-L458 VanDerWaalsContact O-N 3.1Å; L455-L458 WeakPolarHBondContact O-CB 3.4Å; L455-L458 PolarHBondContact O-N 3.48Å; V456-L458 PolarHBondContact O-N 2.77Å; L458-I461 PolarHBondContact O-N 2.79Å; L458-G462 PolarHBondContact O-N 2.92Å
459	F	86.4	Confident	83.8	Confident	143 Å²	143	71.1 Å²	71.1	63%	0.627	41%	0.412	S	S	*	.	H	α-helix	trans	-62.9	-41.7	175.4	-80.1	-67.9	0	0	0	112.3	L455 V456 I461 G462 Y463	L455-F459 HydrophobicContact CD2-CD2 3.92Å; L455-F459 HydrophobicContact CD2-CE2 3.76Å; L455-F459 HydrophobicContact CG-CD2 4.12Å; L455-F459 HydrophobicContact CG-CE2 3.91Å; L455-F459 VanDerWaalsContact O-CD2 3.24Å; L455-F459 WeakPolarHBondContact O-CD2 3.45Å; L455-F459 PolarHBondContact O-N 3.03Å; L455-F459 VanDerWaalsContact O-N 3.09Å; V456-F459 PolarHBondContact O-N 2.03Å; F459-I461 PolarHBondContact O-N 3.38Å; F459-G462 PolarHBondContact O-N 3.38Å; F459-Y463 VanDerWaalsContact O-CB 3.25Å; F459-Y463 WeakPolarHBondContact O-CB 3.45Å; F459-Y463 PolarHBondContact O-N 3.36Å
460	A	85.9	Confident	84.7	Confident	12 Å²	12	65.4 Å²	65.4	10%	0.099	39%	0.385	C	S	.	.	H	α-helix	trans	-63.3	-39.7	176.2	0	0	0	0	0	112.2	V440 L444 V456 A457 Y463 L464	V440-A460 HydrophobicContact CG1-CB 3.98Å; L444-A460 HydrophobicContact CD1-CB 4.23Å; V456-A460 VanDerWaalsContact O-CB 3.32Å; V456-A460 WeakPolarHBondContact O-CB 3.16Å; V456-A460 PolarHBondContact O-N 2.86Å; A457-A460 PolarHBondContact O-N 3.24Å; A460-Y463 PolarHBondContact O-N 2.82Å; A460-L464 VanDerWaalsContact O-CB 3.3Å; A460-L464 WeakPolarHBondContact O-CB 3.49Å; A460-L464 VanDerWaalsContact O-CG 3.24Å; A460-L464 WeakPolarHBondContact O-CG 3.28Å; A460-L464 PolarHBondContact O-N 3.43Å
461	I	87.5	Confident	85.6	Confident	120 Å²	120	60.9 Å²	60.9	62%	0.615	36%	0.358	S	S	*	.	H	α-helix	trans	-64.4	-44.9	174.1	-70.3	163	0	0	0	110.7	A457 L458 F459 G465	A457-I461 WeakPolarHBondContact O-CB 3.48Å; A457-I461 WeakPolarHBondContact O-CD1 3.17Å; A457-I461 VanDerWaalsContact O-CG1 3.23Å; A457-I461 WeakPolarHBondContact O-CG1 3.26Å; A457-I461 PolarHBondContact O-N 3.29Å; L458-I461 PolarHBondContact O-N 2.79Å; F459-I461 PolarHBondContact O-N 3.38Å; I461-G465 PolarHBondContact O-N 3.46Å
462	G	89.8	Confident	86.4	Confident	46 Å²	46	62.2 Å²	62.2	47%	0.474	34%	0.344	S	S	.	.	H	α-helix	trans	-62	-44.3	176.2	0	0	0	0	0	112.6	L458 F459 G465 L466	L458-G462 PolarHBondContact O-N 2.92Å; F459-G462 PolarHBondContact O-N 3.38Å; G462-G465 PolarHBondContact O-N 3.41Å; G462-L466 PolarHBondContact O-N 3.2Å
463	Y	90.8	Very high	87	Confident	27 Å²	27	55.5 Å²	55.5	11%	0.106	32%	0.319	C	S	.	.	H	α-helix	trans	-59.1	-55.1	174.8	174.5	-88.3	0	0	0	111.8	L393 F397 N436 V440 F459 A460 G465 L466 T467	L393-Y463 HydrophobicContact CD1-CD2 4.43Å; L393-Y463 HydrophobicContact CD1-CE1 4.08Å; L393-Y463 HydrophobicContact CD1-CE2 3.72Å; L393-Y463 HydrophobicContact CG-CD2 4.41Å; L393-Y463 HydrophobicContact CG-CE2 3.73Å; L393-Y463 VanDerWaalsContact O-CE2 3.23Å; L393-Y463 WeakPolarHBondContact O-CE2 3.24Å; L393-Y463 PolarHBondContact O-OH 3.39Å; F397-Y463 AromaticContact CE2-CD2 3.69Å; F397-Y463 HydrophobicContact CE2-CD2 3.69Å; F397-Y463 AromaticContact CE2-CE2 3.43Å; F397-Y463 HydrophobicContact CE2-CE2 3.43Å; F397-Y463 VanDerWaalsContact CE2-CE2 3.43Å; F397-Y463 AromaticContact CZ-CD2 3.46Å; F397-Y463 HydrophobicContact CZ-CD2 3.46Å; F397-Y463 VanDerWaalsContact CZ-CD2 3.46Å; F397-Y463 AromaticContact CZ-CE2 3.43Å; F397-Y463 HydrophobicContact CZ-CE2 3.43Å; F397-Y463 VanDerWaalsContact CZ-CE2 3.43Å; F397-Y463 HydrophobicContact CZ-CG 4.34Å; N436-Y463 HydrophobicContact CB-CE1 4.49Å; N436-Y463 WeakPolarHBondContact CB-OH 3.27Å; N436-Y463 VanDerWaalsContact CG-OH 3.24Å; N436-Y463 PolarHBondContact OD1-OH 3.23Å; V440-Y463 HydrophobicContact CG2-CD1 4.04Å; V440-Y463 HydrophobicContact CG2-CE1 4.01Å; F459-Y463 VanDerWaalsContact O-CB 3.25Å; F459-Y463 WeakPolarHBondContact O-CB 3.45Å; F459-Y463 PolarHBondContact O-N 3.36Å; A460-Y463 PolarHBondContact O-N 2.82Å; Y463-G465 VanDerWaalsContact C-N 3.31Å; Y463-G465 PolarHBondContact O-N 2.91Å; Y463-L466 PolarHBondContact O-N 3.41Å; Y463-T467 WeakPolarHBondContact O-CB 3.49Å; Y463-T467 PolarHBondContact O-N 3.11Å; Y463-T467 PolarHBondContact O-OG1 3.37Å; Y463-T467 VanDerWaalsContact O-OG1 3.11Å
464	L	90.6	Very high	87.3	Confident	63 Å²	63	50.7 Å²	50.7	33%	0.33	30%	0.297	S	S	.	.	H	α-helix	trans	-63.5	-37.2	-179.8	-71.2	174.4	0	0	0	111.5	L437 V440 A460 A468	L437-L464 HydrophobicContact CD1-CD2 4.03Å; V440-L464 HydrophobicContact CG1-CD1 4.14Å; V440-L464 HydrophobicContact CG1-CG 4.48Å; A460-L464 VanDerWaalsContact O-CB 3.3Å; A460-L464 WeakPolarHBondContact O-CB 3.49Å; A460-L464 VanDerWaalsContact O-CG 3.24Å; A460-L464 WeakPolarHBondContact O-CG 3.28Å; A460-L464 PolarHBondContact O-N 3.43Å; L464-A468 WeakPolarHBondContact O-CB 3.41Å; L464-A468 PolarHBondContact O-N 3.43Å
465	G	91.5	Very high	87.6	Confident	43 Å²	43	50.3 Å²	50.3	44%	0.443	29%	0.287	S	S	.	.	H	α-helix	trans	-62.9	-44.5	175.1	0	0	0	0	0	112.9	I461 G462 Y463 Y469	I461-G465 PolarHBondContact O-N 3.46Å; G462-G465 PolarHBondContact O-N 3.41Å; Y463-G465 VanDerWaalsContact C-N 3.31Å; Y463-G465 PolarHBondContact O-N 2.91Å; G465-Y469 WeakPolarHBondContact O-CB 3.16Å; G465-Y469 PolarHBondContact O-N 3.13Å
466	L	92.3	Very high	87.6	Confident	16 Å²	16	46.1 Å²	46.1	8%	0.084	27%	0.265	C	S	.	.	H	α-helix	trans	-67.6	-45.1	176.2	-176	61.6	0	0	0	111.6	P89 L92 F397 G462 Y463 A468 Y469 L470	P89-L466 HydrophobicContact CB-CD1 4.2Å; L92-L466 HydrophobicContact CB-CD1 4.49Å; L92-L466 HydrophobicContact CB-CD2 3.86Å; F397-L466 HydrophobicContact CD1-CD2 3.94Å; F397-L466 HydrophobicContact CD1-CG 4.18Å; F397-L466 HydrophobicContact CE1-CB 4.07Å; F397-L466 HydrophobicContact CE1-CD2 3.55Å; F397-L466 HydrophobicContact CE1-CG 3.69Å; F397-L466 HydrophobicContact CZ-CD2 4.11Å; G462-L466 PolarHBondContact O-N 3.2Å; Y463-L466 PolarHBondContact O-N 3.41Å; L466-A468 PolarHBondContact O-N 2.91Å; L466-Y469 PolarHBondContact O-N 2.84Å; L466-L470 HydrophobicContact CG-CD1 4.43Å; L466-L470 WeakPolarHBondContact O-CG 3.37Å; L466-L470 PolarHBondContact O-N 3.36Å
467	T	90.9	Very high	87.4	Confident	11 Å²	11	45 Å²	45	7%	0.067	26%	0.259	C	S	.	.	H	α-helix	trans	-62.5	-42.3	177.3	-62.6	0	0	0	0	111.5	P396 F397 L400 Y463 L470 A471	P396-T467 HydrophobicContact CB-CG2 4.14Å; F397-T467 WeakPolarHBondContact CE1-OG1 3.25Å; L400-T467 HydrophobicContact CD1-CG2 4.14Å; Y463-T467 WeakPolarHBondContact O-CB 3.49Å; Y463-T467 PolarHBondContact O-N 3.11Å; Y463-T467 PolarHBondContact O-OG1 3.37Å; Y463-T467 VanDerWaalsContact O-OG1 3.11Å; T467-L470 PolarHBondContact O-N 3.08Å; T467-A471 VanDerWaalsContact O-CB 3.28Å; T467-A471 WeakPolarHBondContact O-CB 3.49Å; T467-A471 PolarHBondContact O-N 2.94Å
468	A	90.8	Very high	87.3	Confident	61 Å²	61	45.8 Å²	45.8	50%	0.504	26%	0.259	S	S	.	.	H	α-helix	trans	-64.6	-40.7	175	0	0	0	0	0	112.2	L464 L466 A471 W472	L464-A468 WeakPolarHBondContact O-CB 3.41Å; L464-A468 PolarHBondContact O-N 3.43Å; L466-A468 PolarHBondContact O-N 2.91Å; A468-A471 PolarHBondContact O-N 3.36Å; A468-W472 WeakPolarHBondContact O-CB 3.34Å; A468-W472 PolarHBondContact O-N 3.02Å
469	Y	90.8	Very high	86.5	Confident	54 Å²	54	42.1 Å²	42.1	21%	0.212	25%	0.252	C	S	.	.	H	α-helix	trans	-60.5	-46.6	173.9	172.2	-100.1	0	0	0	111.9	Y85 P86 P89 G465 L466 W472 T473	Y85-Y469 AromaticContact CD1-CE1 3.84Å; Y85-Y469 HydrophobicContact CD1-CE1 3.84Å; Y85-Y469 AromaticContact CE1-CE1 3.98Å; Y85-Y469 HydrophobicContact CE1-CE1 3.98Å; P86-Y469 WeakPolarHBondContact CD-OH 3.3Å; P89-Y469 HydrophobicContact CB-CD1 4.09Å; P89-Y469 HydrophobicContact CB-CE1 3.68Å; P89-Y469 HydrophobicContact CG-CD1 4.14Å; P89-Y469 HydrophobicContact CG-CE1 3.71Å; G465-Y469 WeakPolarHBondContact O-CB 3.16Å; G465-Y469 PolarHBondContact O-N 3.13Å; L466-Y469 PolarHBondContact O-N 2.84Å; Y469-W472 WeakPolarHBondContact O-CB 2.98Å; Y469-W472 PolarHBondContact O-N 3.16Å; Y469-T473 HydrophobicContact CE1-CG2 4.46Å; Y469-T473 HydrophobicContact CE2-CG2 4.38Å; Y469-T473 PolarHBondContact O-N 2.96Å
470	L	90.4	Very high	85.8	Confident	1 Å²	1	37.1 Å²	37.1	1%	0.005	24%	0.237	C	C	.	.	H	α-helix	trans	-66.1	-44.8	178.2	-66.5	176.4	0	0	0	111.7	Y85 F397 L400 P401 L466 T467 W472 T473 C474	Y85-L470 HydrophobicContact CE1-CD2 3.79Å; Y85-L470 HydrophobicContact CE2-CD2 4.07Å; Y85-L470 VanDerWaalsContact CZ-CD2 3.5Å; Y85-L470 WeakPolarHBondContact OH-CD2 3.38Å; F397-L470 HydrophobicContact CD1-CD1 3.75Å; F397-L470 HydrophobicContact CE1-CD1 4.43Å; L400-L470 HydrophobicContact CB-CB 3.87Å; L400-L470 HydrophobicContact CD1-CB 3.78Å; L400-L470 HydrophobicContact CG-CB 4.49Å; P401-L470 HydrophobicContact CG-CD2 4.41Å; L466-L470 HydrophobicContact CG-CD1 4.43Å; L466-L470 WeakPolarHBondContact O-CG 3.37Å; L466-L470 PolarHBondContact O-N 3.36Å; T467-L470 PolarHBondContact O-N 3.08Å; L470-W472 VanDerWaalsContact C-N 3.3Å; L470-W472 PolarHBondContact O-N 3.4Å; L470-T473 PolarHBondContact O-N 3.35Å; L470-T473 VanDerWaalsContact O-N 3.15Å; L470-T473 PolarHBondContact O-OG1 3.38Å; L470-C474 PolarHBondContact O-N 2.96Å
471	A	89.3	Confident	84.5	Confident	18 Å²	18	41 Å²	41	15%	0.149	26%	0.259	C	S	.	.	H	α-helix	trans	-60.2	-40.1	176	0	0	0	0	0	111.8	L400 T467 A468 C474 C475	L400-A471 HydrophobicContact CD1-CB 4.31Å; T467-A471 VanDerWaalsContact O-CB 3.28Å; T467-A471 WeakPolarHBondContact O-CB 3.49Å; T467-A471 PolarHBondContact O-N 2.94Å; A468-A471 PolarHBondContact O-N 3.36Å; A471-C474 WeakPolarHBondContact O-CB 3.29Å; A471-C474 PolarHBondContact O-N 3.16Å; A471-C475 PolarHBondContact O-N 3.07Å; A471-C475 PolarHBondContact O-SG 3.07Å; A471-C475 VanDerWaalsContact O-SG 3.36Å
472	W	88.3	Confident	83.2	Confident	114 Å²	114	44.7 Å²	44.7	43%	0.432	27%	0.271	S	S	.	.	H	α-helix	trans	-60	-45.7	173	-179.8	-95.2	0	0	0	112.3	A468 Y469 L470 C474 C475 I476 L483	A468-W472 WeakPolarHBondContact O-CB 3.34Å; A468-W472 PolarHBondContact O-N 3.02Å; Y469-W472 WeakPolarHBondContact O-CB 2.98Å; Y469-W472 PolarHBondContact O-N 3.16Å; L470-W472 VanDerWaalsContact C-N 3.3Å; L470-W472 PolarHBondContact O-N 3.4Å; W472-C474 VanDerWaalsContact C-N 3.3Å; W472-C474 PolarHBondContact O-N 3.27Å; W472-C475 PolarHBondContact O-N 2.95Å; W472-I476 WeakPolarHBondContact O-CG1 3.5Å; W472-I476 PolarHBondContact O-N 3.28Å; W472-I476 VanDerWaalsContact O-N 3.07Å; W472-L483 HydrophobicContact CE3-CD1 4.05Å; W472-L483 HydrophobicContact CH2-CB 3.69Å; W472-L483 HydrophobicContact CH2-CD1 4.28Å; W472-L483 HydrophobicContact CH2-CD2 3.65Å; W472-L483 HydrophobicContact CH2-CG 4.04Å; W472-L483 HydrophobicContact CZ2-CB 3.66Å; W472-L483 HydrophobicContact CZ2-CD2 4.49Å; W472-L483 HydrophobicContact CZ2-CG 4.49Å; W472-L483 WeakPolarHBondContact CZ2-O 3.28Å; W472-L483 HydrophobicContact CZ3-CB 4.16Å; W472-L483 HydrophobicContact CZ3-CD1 3.88Å; W472-L483 HydrophobicContact CZ3-CD2 3.77Å; W472-L483 HydrophobicContact CZ3-CG 4.13Å
473	T	84.9	Confident	81.8	Confident	6 Å²	6	44.8 Å²	44.8	4%	0.037	26%	0.26	C	S	.	.	H	α-helix	trans	-63.1	-35.4	174.7	60.3	0	0	0	0	112.7	Y85 Y469 L470 I476 A477 F491	Y85-T473 HydrophobicContact CE1-CG2 4.27Å; Y85-T473 PolarHBondContact OH-OG1 2.87Å; Y469-T473 HydrophobicContact CE1-CG2 4.46Å; Y469-T473 HydrophobicContact CE2-CG2 4.38Å; Y469-T473 PolarHBondContact O-N 2.96Å; L470-T473 PolarHBondContact O-N 3.35Å; L470-T473 VanDerWaalsContact O-N 3.15Å; L470-T473 PolarHBondContact O-OG1 3.38Å; T473-I476 PolarHBondContact O-N 3.31Å; T473-A477 PolarHBondContact O-N 2.86Å; T473-F491 HydrophobicContact CG2-CZ 4.29Å
474	C	84.9	Confident	80.1	Confident	0 Å²	0	46.7 Å²	46.7	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-67.4	-42.7	175.4	-163.8	0	0	0	0	112.2	T404 M429 L470 A471 W472 I476 A477 H478	T404-C474 VanDerWaalsContact OG1-CA 3.22Å; T404-C474 WeakPolarHBondContact OG1-CA 3.5Å; T404-C474 WeakPolarHBondContact OG1-CB 3.29Å; T404-C474 PolarHBondContact OG1-N 3.38Å; M429-C474 HydrophobicContact SD-CB 3.63Å; M429-C474 VanDerWaalsContact SD-SG 3.62Å; L470-C474 PolarHBondContact O-N 2.96Å; A471-C474 WeakPolarHBondContact O-CB 3.29Å; A471-C474 PolarHBondContact O-N 3.16Å; W472-C474 VanDerWaalsContact C-N 3.3Å; W472-C474 PolarHBondContact O-N 3.27Å; C474-I476 VanDerWaalsContact C-N 3.33Å; C474-I476 PolarHBondContact O-N 3.32Å; C474-A477 PolarHBondContact O-N 3.33Å; C474-H478 PolarHBondContact O-N 3.34Å
475	C	84.8	Confident	78.3	Confident	40 Å²	40	50.7 Å²	50.7	27%	0.27	29%	0.292	S	S	.	.	H	α-helix	trans	-59	-42.1	174.1	-73.4	0	0	0	0	112.2	A471 W472 H478 G479 A480 L483	A471-C475 PolarHBondContact O-N 3.07Å; A471-C475 PolarHBondContact O-SG 3.07Å; A471-C475 VanDerWaalsContact O-SG 3.36Å; W472-C475 PolarHBondContact O-N 2.95Å; C475-H478 PolarHBondContact O-N 3.11Å; C475-G479 PolarHBondContact O-N 3.09Å; C475-A480 HydrophobicContact CB-CB 4.46Å; C475-A480 WeakPolarHBondContact O-CB 3.47Å; C475-A480 PolarHBondContact O-N 2.64Å; C475-A480 VanDerWaalsContact O-N 3.1Å; C475-L483 HydrophobicContact CB-CD1 4.12Å
476	I	81.8	Confident	76.3	Confident	13 Å²	13	52.9 Å²	52.9	7%	0.067	30%	0.3	C	S	.	.	H	α-helix	trans	-61.3	-47.4	174.4	-70.4	170.7	0	0	0	110.6	W472 T473 C474 H478 G479 L483 T484 L492	W472-I476 WeakPolarHBondContact O-CG1 3.5Å; W472-I476 PolarHBondContact O-N 3.28Å; W472-I476 VanDerWaalsContact O-N 3.07Å; T473-I476 PolarHBondContact O-N 3.31Å; C474-I476 VanDerWaalsContact C-N 3.33Å; C474-I476 PolarHBondContact O-N 3.32Å; I476-H478 VanDerWaalsContact C-N 3.28Å; I476-H478 PolarHBondContact O-N 2.64Å; I476-G479 PolarHBondContact O-N 2.86Å; I476-L483 HydrophobicContact CG1-CB 4.09Å; I476-T484 HydrophobicContact CG1-CG2 4.45Å; I476-T484 HydrophobicContact CG2-CG2 3.98Å; I476-L492 HydrophobicContact CG2-CD1 3.43Å; I476-L492 VanDerWaalsContact CG2-CD1 3.43Å
477	A	78	Confident	74.3	Confident	11 Å²	11	56.7 Å²	56.7	9%	0.091	33%	0.328	C	S	.	.	H	α-helix	trans	-64	-28.3	177.1	0	0	0	0	0	114.1	T404 M408 K422 T473 C474 G479	T404-A477 HydrophobicContact CG2-CB 3.85Å; M408-A477 HydrophobicContact CG-CB 3.6Å; M408-A477 HydrophobicContact SD-CB 4.31Å; K422-A477 PolarHBondContact NZ-O 3.42Å; K422-A477 VanDerWaalsContact NZ-O 3.09Å; T473-A477 PolarHBondContact O-N 2.86Å; C474-A477 PolarHBondContact O-N 3.33Å; A477-G479 VanDerWaalsContact C-N 3.28Å
478	H	78.3	Confident	72.4	Confident	38 Å²	38	60 Å²	60	18%	0.176	34%	0.343	C	S	.	.	H	α-helix	trans	-73.9	-17.5	173.4	-75.9	-170.9	0	0	0	113.2	S407 T425 S426 C474 C475 I476	S407-H478 PolarHBondContact OG-CD2 3.04Å; S407-H478 PolarHBondContact OG-NE2 3.28Å; T425-H478 PolarHBondContact OG1-CE1 2.94Å; T425-H478 VanDerWaalsContact OG1-CE1 3.26Å; T425-H478 PolarHBondContact OG1-NE2 3.12Å; T425-H478 VanDerWaalsContact OG1-NE2 3.1Å; S426-H478 PolarHBondContact N-CE1 3.2Å; C474-H478 PolarHBondContact O-N 3.34Å; C475-H478 PolarHBondContact O-N 3.11Å; I476-H478 VanDerWaalsContact C-N 3.28Å; I476-H478 PolarHBondContact O-N 2.64Å
479	G	69.3	Low	70.4	Confident	48 Å²	48	64 Å²	64	50%	0.495	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	119.5	11.4	173.3	0	0	0	0	0	115.2	C475 I476 A477 T481	C475-G479 PolarHBondContact O-N 3.09Å; I476-G479 PolarHBondContact O-N 2.86Å; A477-G479 VanDerWaalsContact C-N 3.28Å; G479-T481 PolarHBondContact O-N 2.95Å
480	A	70.5	Confident	68.5	Low	38 Å²	38	65.6 Å²	65.6	31%	0.314	36%	0.358	S	S	.	.			trans	-74.7	64.7	175	0	0	0	0	0	111.6	C475 F482 L483	C475-A480 HydrophobicContact CB-CB 4.46Å; C475-A480 WeakPolarHBondContact O-CB 3.47Å; C475-A480 PolarHBondContact O-N 2.64Å; C475-A480 VanDerWaalsContact O-N 3.1Å; A480-F482 PolarHBondContact O-N 3.02Å; A480-F482 VanDerWaalsContact O-N 3.16Å; A480-L483 HydrophobicContact CB-CD1 3.8Å; A480-L483 HydrophobicContact CB-CG 4.08Å; A480-L483 WeakPolarHBondContact O-CB 3.38Å; A480-L483 PolarHBondContact O-N 2.78Å
481	T	60.1	Low	66.6	Low	93 Å²	93	66.5 Å²	66.5	57%	0.571	36%	0.362	S	S	*	.	G	3₁₀ helix	trans	-62.9	-20.7	-175.2	51.2	0	0	0	0	113.9	G479 L483 T484	G479-T481 PolarHBondContact O-N 2.95Å; T481-L483 PolarHBondContact O-N 2.87Å; T481-L483 VanDerWaalsContact O-N 3.14Å; T481-T484 PolarHBondContact O-N 2.87Å; T481-T484 VanDerWaalsContact O-N 3.12Å; T481-T484 PolarHBondContact O-OG1 2.94Å
482	F	59.5	Low	64.7	Low	197 Å²	197	69.3 Å²	69.3	86%	0.864	37%	0.374	S	S	*	.	G	3₁₀ helix	trans	-57.3	-24.4	170.2	-177.5	-104.9	0	0	0	113.2	A480 T484	A480-F482 PolarHBondContact O-N 3.02Å; A480-F482 VanDerWaalsContact O-N 3.16Å; F482-T484 VanDerWaalsContact C-N 3.34Å
483	L	60.3	Low	62.9	Low	48 Å²	48	73.2 Å²	73.2	25%	0.251	39%	0.39	S	S	.	.	G	3₁₀ helix	trans	-86.8	1.7	-179.4	-52.7	-177.7	0	0	0	113.4	W472 C475 I476 A480 T481 H485	W472-L483 HydrophobicContact CE3-CD1 4.05Å; W472-L483 HydrophobicContact CH2-CB 3.69Å; W472-L483 HydrophobicContact CH2-CD1 4.28Å; W472-L483 HydrophobicContact CH2-CD2 3.65Å; W472-L483 HydrophobicContact CH2-CG 4.04Å; W472-L483 HydrophobicContact CZ2-CB 3.66Å; W472-L483 HydrophobicContact CZ2-CD2 4.49Å; W472-L483 HydrophobicContact CZ2-CG 4.49Å; W472-L483 WeakPolarHBondContact CZ2-O 3.28Å; W472-L483 HydrophobicContact CZ3-CB 4.16Å; W472-L483 HydrophobicContact CZ3-CD1 3.88Å; W472-L483 HydrophobicContact CZ3-CD2 3.77Å; W472-L483 HydrophobicContact CZ3-CG 4.13Å; C475-L483 HydrophobicContact CB-CD1 4.12Å; I476-L483 HydrophobicContact CG1-CB 4.09Å; A480-L483 HydrophobicContact CB-CD1 3.8Å; A480-L483 HydrophobicContact CB-CG 4.08Å; A480-L483 WeakPolarHBondContact O-CB 3.38Å; A480-L483 PolarHBondContact O-N 2.78Å; T481-L483 PolarHBondContact O-N 2.87Å; T481-L483 VanDerWaalsContact O-N 3.14Å; L483-H485 PolarHBondContact O-N 3.39Å
484	T	55	Low	61.1	Low	67 Å²	67	73.6 Å²	73.6	41%	0.411	40%	0.395	S	S	.	.			trans	-83.3	109.9	-176.4	62.2	0	0	0	0	112.5	I476 T481 F482 L492	I476-T484 HydrophobicContact CG1-CG2 4.45Å; I476-T484 HydrophobicContact CG2-CG2 3.98Å; T481-T484 PolarHBondContact O-N 2.87Å; T481-T484 VanDerWaalsContact O-N 3.12Å; T481-T484 PolarHBondContact O-OG1 2.94Å; F482-T484 VanDerWaalsContact C-N 3.34Å; T484-L492 HydrophobicContact CG2-CD1 4.5Å
485	H	53.6	Low	59.1	Low	148 Å²	148	77.1 Å²	77.1	69%	0.685	41%	0.414	S	S	*	.			trans	-84.2	150.6	167.9	-160.9	-107	0	0	0	111.6	L483 S487 H488	L483-H485 PolarHBondContact O-N 3.39Å; H485-S487 PolarHBondContact O-N 3.21Å; H485-H488 PolarHBondContact O-N 2.81Å
486	S	49.3	Very low	56.9	Low	88 Å²	88	79.5 Å²	79.5	62%	0.615	43%	0.428	S	S	*	.	G	3₁₀ helix	trans	-54.6	-29.8	-167.2	-161.5	0	0	0	0	115	H488	S486-H488 PolarHBondContact O-N 2.98Å
487	S	50.6	Low	54.8	Low	97 Å²	97	85.1 Å²	85.1	68%	0.678	46%	0.459	S	S	*	.	G	3₁₀ helix	trans	-69.7	-10.2	179.9	-162.8	0	0	0	0	115	H485	H485-S487 PolarHBondContact O-N 3.21Å
488	H	50.8	Low	52.9	Low	79 Å²	79	93.2 Å²	93.2	37%	0.366	49%	0.494	S	S	.	.	G	3₁₀ helix	trans	-112.7	17.3	-173.1	-71	-24.3	0	0	0	115.5	H485 S486 H490 F491	H485-H488 PolarHBondContact O-N 2.81Å; S486-H488 PolarHBondContact O-N 2.98Å; H488-H490 PolarHBondContact O-N 3.49Å; H488-F491 WeakPolarHBondContact O-CB 3.45Å; H488-F491 PolarHBondContact O-N 3.02Å
489	K	49.1	Very low	50.9	Low	145 Å²	145	99.4 Å²	99.4	63%	0.63	52%	0.524	S	S	*	.	H	α-helix	trans	-56.7	-31.6	170.3	-69.5	-177.7	178.2	179.9	0	113.1	F491 L492 Y493	K489-F491 PolarHBondContact O-N 3.18Å; K489-L492 PolarHBondContact O-N 3.09Å; K489-L492 VanDerWaalsContact O-N 3.13Å; K489-Y493 PolarHBondContact O-N 3.46Å; K489-Y493 VanDerWaalsContact O-N 3.1Å
490	H	49.5	Very low	49.1	Very low	89 Å²	89	104.2 Å²	104.2	41%	0.412	53%	0.533	S	S	.	.	H	α-helix	trans	-58.3	-27.8	172.9	-172	-73.4	0	0	0	113.5	H488 P496	H488-H490 PolarHBondContact O-N 3.49Å; H490-P496 WeakPolarHBondContact NE2-CD 3.36Å
491	F	51.5	Low	47.1	Very low	19 Å²	19	106.4 Å²	106.4	8%	0.083	56%	0.56	C	S	.	*	H	α-helix	trans	-78.4	-31.2	177.9	-153.8	-94.8	0	0	0	111.7	Y84 Y85 T404 F405 M408 T473 H488 K489	Y84-F491 HydrophobicContact CD1-CD2 4.3Å; Y84-F491 HydrophobicContact CD1-CE2 4.42Å; Y85-F491 HydrophobicContact CD1-CE2 4.32Å; Y85-F491 HydrophobicContact CE1-CE2 4.1Å; Y85-F491 HydrophobicContact CE1-CZ 4.23Å; T404-F491 HydrophobicContact CG2-CE1 3.81Å; T404-F491 HydrophobicContact CG2-CZ 3.93Å; F405-F491 HydrophobicContact CE1-CE2 4.43Å; F405-F491 HydrophobicContact CE1-CZ 4.03Å; M408-F491 HydrophobicContact CE-CD1 3.82Å; M408-F491 HydrophobicContact CE-CE1 3.81Å; M408-F491 HydrophobicContact CE-CG 4.49Å; M408-F491 HydrophobicContact CE-CZ 4.47Å; M408-F491 WeakPolarHBondContact CE-O 3.37Å; M408-F491 HydrophobicContact SD-CD1 4.19Å; M408-F491 HydrophobicContact SD-CE1 3.6Å; M408-F491 HydrophobicContact SD-CZ 4.21Å; T473-F491 HydrophobicContact CG2-CZ 4.29Å; H488-F491 WeakPolarHBondContact O-CB 3.45Å; H488-F491 PolarHBondContact O-N 3.02Å; K489-F491 PolarHBondContact O-N 3.18Å
492	L	49.5	Very low	45.6	Very low	77 Å²	77	105.4 Å²	105.4	40%	0.403	57%	0.567	S	S	.	*	H	α-helix	trans	-86	-35.9	-177.7	-119.1	80	0	0	0	114	I476 T484 K489	I476-L492 HydrophobicContact CG2-CD1 3.43Å; I476-L492 VanDerWaalsContact CG2-CD1 3.43Å; T484-L492 HydrophobicContact CG2-CD1 4.5Å; K489-L492 PolarHBondContact O-N 3.09Å; K489-L492 VanDerWaalsContact O-N 3.13Å
493	Y	48.8	Very low	44.3	Very low	197 Å²	197	102.7 Å²	102.7	77%	0.773	57%	0.567	S	S	*	*	H	α-helix	trans	-99.3	-0.3	-170.8	-77.3	-86.9	0	0	0	114.7	K489	K489-Y493 PolarHBondContact O-N 3.46Å; K489-Y493 VanDerWaalsContact O-N 3.1Å
494	G	48.1	Very low	42.9	Very low	14 Å²	14	110 Å²	110	14%	0.144	60%	0.599	C	S	.	*			trans	85.3	176.4	-177.3	0	0	0	0	0	113.6
495	L	42.3	Very low	41.7	Very low	74 Å²	74	110.7 Å²	110.7	39%	0.387	62%	0.62	S	S	.	*			trans	-66	139.1	175	-72.9	157.1	0	0	0	110.6	L83	L83-L495 HydrophobicContact CB-CD1 4.19Å; L83-L495 HydrophobicContact CD1-CD1 4.49Å; L83-L495 HydrophobicContact CD2-CD1 4.03Å; L83-L495 HydrophobicContact CG-CD1 4.46Å
496	P	38.4	Very low	40.7	Very low	89 Å²	89	109.4 Å²	109.4	58%	0.578	63%	0.628	S	S	*	*			trans	-58.5	146.5	165	-20	31.9	0	0	0	111.4	H490 E498	H490-P496 WeakPolarHBondContact NE2-CD 3.36Å; P496-E498 VanDerWaalsContact C-N 3.33Å; P496-E498 PolarHBondContact O-N 2.94Å
497	N	37.7	Very low	40	Very low	131 Å²	131	112.7 Å²	112.7	70%	0.701	68%	0.676	S	S	*	*	S	Bend	trans	-69.9	79.2	179.3	-74.9	-14.1	0	0	0	112.5
498	E	37.8	Very low	39.4	Very low	181 Å²	181	113.5 Å²	113.5	85%	0.846	68%	0.676	S	S	*	*			trans	-104.6	-12.1	169.3	-70.2	-163.1	148.2	0	0	114.2	P496	P496-E498 VanDerWaalsContact C-N 3.33Å; P496-E498 PolarHBondContact O-N 2.94Å
499	E	38.3	Very low	38.9	Very low	169 Å²	169	115.3 Å²	115.3	79%	0.79	69%	0.692	S	S	*	*	S	Bend	trans	-96.4	5.1	176.4	-73.9	-172.7	156.7	0	0	114.7
500	Q	31.2	Very low	38.3	Very low	149 Å²	149	113.7 Å²	113.7	70%	0.696	70%	0.696	S	S	*	*	S	Bend	trans	-91.7	-5.4	175	-78.5	-173.3	-22.1	0	0	114.7	G502	Q500-G502 PolarHBondContact O-N 3.08Å
501	G	27.8	Very low	37.6	Very low	84 Å²	84	115.1 Å²	115.1	87%	0.866	71%	0.712	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.7	13.6	-175.8	0	0	0	0	0	116.8
502	G	28.6	Very low	36.8	Very low	71 Å²	71	121.1 Å²	121.1	73%	0.732	75%	0.752	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.7	-12	-171.5	0	0	0	0	0	116.8	Q500	Q500-G502 PolarHBondContact O-N 3.08Å
503	V	31.9	Very low	35.9	Very low	141 Å²	141	124.1 Å²	124.1	86%	0.855	78%	0.775	S	S	*	*	S	Bend	trans	-135.9	58.3	-171.9	-164	0	0	0	0	111.9
504	Q	31.7	Very low	35	Very low	200 Å²	200	118.9 Å²	118.9	94%	0.935	78%	0.775	S	S	*	*			trans	-159.2	91.9	163.4	-113.1	172.2	6.7	0	0	108.9
505	G	30.4	Very low	34	Very low	82 Å²	82	126.9 Å²	126.9	85%	0.845	82%	0.823	S	S	*	*			trans	173.2	32.8	-173.1	0	0	0	0	0	118.9
506	S	30.5	Very low	33.3	Very low	121 Å²	121	131.3 Å²	131.3	85%	0.846	86%	0.86	S	S	*	*			trans	-157.2	106.9	162.4	55.6	0	0	0	0	109.9
507	G	35.2	Very low	32.8	Very low	158 Å²	158	135.2 Å²	135.2	100%	1.629	89%	0.885	S	S	*	*			trans	-91.8	0	161.7	0	0	0	0	0	111.3

Retrieved 507 of 507 residues in 155.3 ms (Link to these results)

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