A0A087WPA8_MOUSE Loading...

Potassium voltage-gated channel, subfamily Q, member 1

AlphaFold DB , UniProt , Accession A0A087WPA8, Species MOUSE (Mus musculus, Mouse), Gene Kcnq1, Length 39 aa.

						>A0A087WPA8_MOUSE|A0A087WPA8|Kcnq1
MLAPEWWSVNLAQPWLPMEFSYKEGGLPHCSGLPHLQCP
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.2	Very low	48.6	Very low	242 Å²	242	149.1 Å²	149.1	100%	1.192	76%	0.762	S	S	*	*				0	96.8	0	-69.6	164.2	-179.5	0	105.9
2	L	48.8	Very low	48.5	Very low	173 Å²	173	142.7 Å²	142.7	91%	0.906	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-71.1	125.8	-179.2	-75.5	94.4	0	0	107.9
3	A	48.6	Very low	48.7	Very low	55 Å²	55	138.8 Å²	138.8	46%	0.455	72%	0.724	S	S	.	*	P	Polyproline II helix	trans	-64.2	135	167.7	0	0	0	0	108	E5 W7	A3-E5 PolarHBondContact O-N 3.48Å; A3-W7 HydrophobicContact CB-CZ2 3.6Å
4	P	46.4	Very low	49	Very low	74 Å²	74	137.2 Å²	137.2	48%	0.481	73%	0.726	S	S	.	*	P	Polyproline II helix	trans	-62.8	134.9	-176.2	25.6	-31.9	0	0	109.2	W6 W7	P4-W6 HydrophobicContact CB-CE3 4.27Å; P4-W6 HydrophobicContact CB-CZ2 4.43Å; P4-W6 PolarHBondContact O-N 3Å; P4-W6 HydrophobicContact CB-CD2 4.13Å; P4-W7 PolarHBondContact O-NE1 3.17Å
5	E	54.5	Low	49.1	Very low	189 Å²	189	139.8 Å²	139.8	88%	0.883	72%	0.722	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.2	41.7	-171.4	-69.8	-178.6	80.3	0	115.4	A3	A3-E5 PolarHBondContact O-N 3.48Å
6	W	48.1	Very low	49.5	Very low	227 Å²	227	135.9 Å²	135.9	86%	0.86	70%	0.703	S	S	*	*	T	Hydrogen-bonded Turn	trans	-121.3	-1.1	-174.2	-41.6	-31.6	0	0	113.7	P4	P4-W6 HydrophobicContact CB-CE3 4.27Å; P4-W6 HydrophobicContact CB-CZ2 4.43Å; P4-W6 PolarHBondContact O-N 3Å; P4-W6 HydrophobicContact CB-CD2 4.13Å
7	W	44.6	Very low	49.5	Very low	169 Å²	169	133.1 Å²	133.1	64%	0.64	70%	0.695	S	S	*	*			trans	-107.4	24.7	-174.8	54.9	-90	0	0	113.8	A3 P4 V9	A3-W7 HydrophobicContact CB-CZ2 3.6Å; P4-W7 PolarHBondContact O-NE1 3.17Å; W7-V9 PolarHBondContact O-N 3Å
8	S	46	Very low	49.4	Very low	109 Å²	109	135.5 Å²	135.5	76%	0.762	71%	0.705	S	S	*	*			trans	-78.3	64.9	161.4	-123.8	0	0	0	109.3	N10	S8-N10 VanDerWaalsContact C-N 3.26Å; S8-N10 PolarHBondContact O-N 3.01Å
9	V	51.9	Low	49.5	Very low	107 Å²	107	137.7 Å²	137.7	65%	0.648	71%	0.711	S	S	*	*			trans	-62.9	97.9	163.6	-176.9	0	0	0	105.1	W7 L11	W7-V9 PolarHBondContact O-N 3Å; V9-L11 HydrophobicContact CG1-CG 4.3Å; V9-L11 PolarHBondContact O-N 2.92Å
10	N	51.6	Low	49.7	Very low	124 Å²	124	134.9 Å²	134.9	66%	0.663	69%	0.693	S	S	*	*			trans	-61	91.4	167.5	-105.6	-82.9	0	0	106.8	S8 A12	S8-N10 VanDerWaalsContact C-N 3.26Å; S8-N10 PolarHBondContact O-N 3.01Å; N10-A12 PolarHBondContact O-N 2.78Å
11	L	52.1	Low	49.8	Very low	171 Å²	171	132.8 Å²	132.8	90%	0.895	69%	0.69	S	S	*	*	S	Bend	trans	-67.3	26.5	175.9	-96.4	150.3	0	0	112.7	V9	V9-L11 HydrophobicContact CG1-CG 4.3Å; V9-L11 PolarHBondContact O-N 2.92Å
12	A	47.8	Very low	50.4	Low	72 Å²	72	128.6 Å²	128.6	60%	0.595	66%	0.663	S	S	*	*			trans	-135.6	53.6	-178.4	0	0	0	0	110.3	N10	N10-A12 PolarHBondContact O-N 2.78Å
13	Q	51.1	Low	50.5	Low	93 Å²	93	129.2 Å²	129.2	44%	0.435	66%	0.658	S	S	.	*			trans	-121	88.4	162.9	-72.8	-142.2	-28.1	0	109.4	W15 L16	Q13-W15 HydrophobicContact CG-CZ2 4.15Å; Q13-W15 PolarHBondContact O-N 2.83Å; Q13-W15 VanDerWaalsContact OE1-NE1 3.13Å; Q13-L16 PolarHBondContact O-N 3.24Å; Q13-L16 HydrophobicContact CB-CD1 3.84Å; Q13-L16 HydrophobicContact CB-CG 4.04Å
14	P	52.5	Low	50.7	Low	116 Å²	116	136.4 Å²	136.4	75%	0.753	68%	0.682	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.4	-2.9	-178.3	27.4	-33.6	0	0	113.7
15	W	50.9	Low	50.9	Low	176 Å²	176	137.2 Å²	137.2	67%	0.667	70%	0.704	S	S	*	*	T	Hydrogen-bonded Turn	trans	-102.8	-2.5	179.6	41.1	73.3	0	0	114	Q13 P17	Q13-W15 HydrophobicContact CG-CZ2 4.15Å; Q13-W15 PolarHBondContact O-N 2.83Å; Q13-W15 VanDerWaalsContact OE1-NE1 3.13Å; W15-P17 VanDerWaalsContact O-CD 3.26Å; W15-P17 WeakPolarHBondContact O-CD 3.47Å
16	L	54.4	Low	50.7	Low	78 Å²	78	130.5 Å²	130.5	41%	0.408	69%	0.686	S	S	.	*	S	Bend	trans	-78.5	115.1	172	-73.7	171.3	0	0	108.6	Q13 M18	Q13-L16 PolarHBondContact O-N 3.24Å; Q13-L16 HydrophobicContact CB-CD1 3.84Å; Q13-L16 HydrophobicContact CB-CG 4.04Å; L16-M18 PolarHBondContact O-N 3.03Å
17	P	49.5	Very low	51.1	Low	88 Å²	88	127.7 Å²	127.7	57%	0.571	69%	0.687	S	S	*	*			trans	-60.5	138.3	175.8	24.5	-31.1	0	0	108.7	W15 E19 F20	W15-P17 VanDerWaalsContact O-CD 3.26Å; W15-P17 WeakPolarHBondContact O-CD 3.47Å; P17-E19 PolarHBondContact O-N 3.42Å; P17-F20 PolarHBondContact O-N 2.85Å
18	M	49.2	Very low	51.6	Low	176 Å²	176	122 Å²	122	87%	0.867	67%	0.671	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55	-14.6	-175.4	-166.5	156.1	178.3	0	114.3	L16 F20 S21	L16-M18 PolarHBondContact O-N 3.03Å; M18-F20 PolarHBondContact O-N 2.09Å; M18-S21 PolarHBondContact O-OG 2.85Å; M18-S21 PolarHBondContact O-N 3.27Å
19	E	49.7	Very low	52	Low	178 Å²	178	124.9 Å²	124.9	83%	0.832	67%	0.672	S	S	*	*	T	Hydrogen-bonded Turn	trans	-65.1	-8.5	168.7	-71.1	-92.5	90.2	0	114.1	P17 S21	P17-E19 PolarHBondContact O-N 3.42Å; E19-S21 PolarHBondContact O-N 2.95Å
20	F	54.6	Low	52.2	Low	81 Å²	81	122.3 Å²	122.3	36%	0.355	66%	0.659	S	S	.	*			trans	-76.2	35.5	164.9	-127.5	-111.6	0	0	111.5	P17 M18 Y22	P17-F20 PolarHBondContact O-N 2.85Å; M18-F20 PolarHBondContact O-N 2.09Å; F20-Y22 VanDerWaalsContact O-N 3.11Å; F20-Y22 PolarHBondContact O-N 2.95Å; F20-Y22 WeakPolarHBondContact O-CD2 3.23Å; F20-Y22 WeakPolarHBondContact CE1-OH 3.26Å; F20-Y22 AromaticContact CE1-CZ 3.39Å; F20-Y22 HydrophobicContact CE1-CE2 3.68Å; F20-Y22 AromaticContact CE1-CE2 3.68Å; F20-Y22 AromaticContact CD1-CZ 3.67Å; F20-Y22 HydrophobicContact CE1-CE1 4.25Å; F20-Y22 VanDerWaalsContact C-N 3.34Å; F20-Y22 HydrophobicContact CD1-CD2 4.22Å; F20-Y22 AromaticContact CD1-CE2 3.41Å; F20-Y22 HydrophobicContact CD1-CE2 3.41Å; F20-Y22 VanDerWaalsContact CD1-CE2 3.41Å
21	S	51.7	Low	52.2	Low	90 Å²	90	121.2 Å²	121.2	63%	0.629	66%	0.66	S	S	*	*			trans	-78.3	92.2	167.2	-69.6	0	0	0	106.7	M18 E19 K23	M18-S21 PolarHBondContact O-OG 2.85Å; M18-S21 PolarHBondContact O-N 3.27Å; E19-S21 PolarHBondContact O-N 2.95Å; S21-K23 PolarHBondContact O-N 2.78Å
22	Y	54.5	Low	52.2	Low	155 Å²	155	116.1 Å²	116.1	61%	0.608	65%	0.649	S	S	*	*			trans	-53.4	101.8	169.8	-69.3	-89.8	0	0	109	F20 E24 P28	F20-Y22 VanDerWaalsContact O-N 3.11Å; F20-Y22 PolarHBondContact O-N 2.95Å; F20-Y22 WeakPolarHBondContact O-CD2 3.23Å; F20-Y22 WeakPolarHBondContact CE1-OH 3.26Å; F20-Y22 AromaticContact CE1-CZ 3.39Å; F20-Y22 HydrophobicContact CE1-CE2 3.68Å; F20-Y22 AromaticContact CE1-CE2 3.68Å; F20-Y22 AromaticContact CD1-CZ 3.67Å; F20-Y22 HydrophobicContact CE1-CE1 4.25Å; F20-Y22 VanDerWaalsContact C-N 3.34Å; F20-Y22 HydrophobicContact CD1-CD2 4.22Å; F20-Y22 AromaticContact CD1-CE2 3.41Å; F20-Y22 HydrophobicContact CD1-CE2 3.41Å; F20-Y22 VanDerWaalsContact CD1-CE2 3.41Å; Y22-E24 PolarHBondContact O-N 2.83Å; Y22-E24 VanDerWaalsContact O-N 3.13Å; Y22-P28 HydrophobicContact CE1-CB 4.14Å; Y22-P28 HydrophobicContact CE1-CG 3.84Å
23	K	50.4	Low	52.7	Low	185 Å²	185	117.4 Å²	117.4	80%	0.804	65%	0.646	S	S	*	*			trans	-71.1	108.4	164.2	-108	-178.2	175.5	174.7	106.6	S21 G25 G26	S21-K23 PolarHBondContact O-N 2.78Å; K23-G25 PolarHBondContact O-N 2.88Å; K23-G25 VanDerWaalsContact O-N 3.09Å; K23-G26 PolarHBondContact O-N 2.97Å; K23-G26 VanDerWaalsContact O-N 3.12Å
24	E	52.3	Low	52.6	Low	206 Å²	206	118.9 Å²	118.9	96%	0.963	66%	0.664	S	S	*	*	T	Hydrogen-bonded Turn	trans	-30	110.7	170	-150.6	175.1	99.9	0	110.8	Y22	Y22-E24 PolarHBondContact O-N 2.83Å; Y22-E24 VanDerWaalsContact O-N 3.13Å
25	G	51	Low	52.5	Low	92 Å²	92	121.9 Å²	121.9	95%	0.948	67%	0.667	S	S	*	*	T	Hydrogen-bonded Turn	trans	104.4	-4.3	175.1	0	0	0	0	117.6	K23	K23-G25 PolarHBondContact O-N 2.88Å; K23-G25 VanDerWaalsContact O-N 3.09Å
26	G	51.7	Low	52.6	Low	48 Å²	48	118.3 Å²	118.3	50%	0.495	66%	0.661	S	S	.	*	S	Bend	trans	-115.3	119.8	171.2	0	0	0	0	111.1	K23	K23-G26 PolarHBondContact O-N 2.97Å; K23-G26 VanDerWaalsContact O-N 3.12Å
27	L	55.1	Low	52.3	Low	168 Å²	168	124 Å²	124	88%	0.88	69%	0.685	S	S	*	*			trans	-47.3	134	165.9	-76.4	164.2	0	0	108.4	H29	L27-H29 PolarHBondContact O-N 3.42Å
28	P	55.4	Low	52.4	Low	49 Å²	49	122.7 Å²	122.7	32%	0.318	68%	0.677	S	S	.	*			trans	-57.7	116.7	176.1	26.4	-34.1	0	0	106.9	Y22 C30	Y22-P28 HydrophobicContact CE1-CB 4.14Å; Y22-P28 HydrophobicContact CE1-CG 3.84Å; P28-C30 PolarHBondContact O-SG 3.09Å; P28-C30 PolarHBondContact O-N 3.27Å; P28-C30 VanDerWaalsContact C-N 3.27Å
29	H	54.2	Low	52.4	Low	169 Å²	169	124 Å²	124	78%	0.782	70%	0.699	S	S	*	*			trans	-70.3	94.8	177.7	-155.2	137.5	0	0	106.1	L27 S31	L27-H29 PolarHBondContact O-N 3.42Å; H29-S31 VanDerWaalsContact CD2-CB 3.47Å; H29-S31 WeakPolarHBondContact CD2-CB 3.1Å; H29-S31 PolarHBondContact CD2-OG 2.87Å; H29-S31 PolarHBondContact NE2-OG 3.13Å; H29-S31 PolarHBondContact O-N 3.12Å
30	C	56.6	Low	52.5	Low	54 Å²	54	121.3 Å²	121.3	37%	0.365	69%	0.692	S	S	.	*			trans	-70.2	36.5	-177.7	-52.2	0	0	0	111.7	P28 G32 C38	P28-C30 PolarHBondContact O-SG 3.09Å; P28-C30 PolarHBondContact O-N 3.27Å; P28-C30 VanDerWaalsContact C-N 3.27Å; C30-G32 PolarHBondContact O-N 3.11Å; C30-C38 WeakPolarHBondContact SG-CB 3.5Å; C30-C38 PolarHBondContact SG-SG 2.86Å; C30-C38 CovalentContact SG-SG 2.09Å; C30-C38 WeakPolarHBondContact CB-SG 3.36Å
31	S	51.1	Low	52.4	Low	100 Å²	100	123.4 Å²	123.4	70%	0.699	71%	0.71	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.1	7.4	-171.8	-95.1	0	0	0	115.6	H29	H29-S31 VanDerWaalsContact CD2-CB 3.47Å; H29-S31 WeakPolarHBondContact CD2-CB 3.1Å; H29-S31 PolarHBondContact CD2-OG 2.87Å; H29-S31 PolarHBondContact NE2-OG 3.13Å; H29-S31 PolarHBondContact O-N 3.12Å
32	G	52.8	Low	52.5	Low	64 Å²	64	125.2 Å²	125.2	66%	0.66	71%	0.714	S	S	*	*	T	Hydrogen-bonded Turn	trans	-131	-2.1	-178.3	0	0	0	0	115.6	C30	C30-G32 PolarHBondContact O-N 3.11Å
33	L	57.2	Low	52.4	Low	99 Å²	99	123.5 Å²	123.5	52%	0.518	72%	0.72	S	S	.	*			trans	-128.4	92.6	-171.1	-67.9	171.3	0	0	110.3	H35 L36	L33-H35 PolarHBondContact O-N 2.86Å; L33-L36 HydrophobicContact CB-CD1 4.45Å; L33-L36 HydrophobicContact CD1-CD1 3.86Å; L33-L36 PolarHBondContact O-N 2.71Å
34	P	50.8	Low	52.5	Low	125 Å²	125	119.6 Å²	119.6	81%	0.812	72%	0.715	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.4	-3.2	-176.8	18	-22	0	0	114.5
35	H	48.9	Very low	52.5	Low	178 Å²	178	113.9 Å²	113.9	82%	0.824	70%	0.699	S	S	*	*	T	Hydrogen-bonded Turn	trans	-114.6	-2.7	-173	-74.7	-116.1	0	0	114.5	L33	L33-H35 PolarHBondContact O-N 2.86Å
36	L	52.7	Low	52.6	Low	102 Å²	102	115.4 Å²	115.4	53%	0.534	68%	0.681	S	S	.	*			trans	-104	99.7	174.4	-71.6	171.4	0	0	108.2	L33 C38	L33-L36 HydrophobicContact CB-CD1 4.45Å; L33-L36 HydrophobicContact CD1-CD1 3.86Å; L33-L36 PolarHBondContact O-N 2.71Å; L36-C38 VanDerWaalsContact C-N 3.32Å; L36-C38 PolarHBondContact O-N 3.43Å
37	Q	48.7	Very low	52.7	Low	197 Å²	197	120.6 Å²	120.6	92%	0.921	70%	0.695	S	S	*	*			trans	-67.1	100	164	-145.1	163.5	31.3	0	105.9
38	C	51.5	Low	52.5	Low	61 Å²	61	116.7 Å²	116.7	41%	0.412	68%	0.68	S	S	.	*			trans	-63.6	129	176	-59.7	0	0	0	106.8	C30 L36	C30-C38 WeakPolarHBondContact SG-CB 3.5Å; C30-C38 PolarHBondContact SG-SG 2.86Å; C30-C38 CovalentContact SG-SG 2.09Å; C30-C38 WeakPolarHBondContact CB-SG 3.36Å; L36-C38 VanDerWaalsContact C-N 3.32Å; L36-C38 PolarHBondContact O-N 3.43Å
39	P	49.8	Very low	52.2	Low	202 Å²	202	122.8 Å²	122.8	100%	1.312	71%	0.713	S	S	*	*			trans	-64.8	0	-177	27	-34.4	0	0	112.6

Retrieved 39 of 39 residues in 80.7 ms (Link to these results)

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