A0A087WPJ2_MOUSE Loading...

Potassium voltage-gated channel, subfamily Q, member 1

AlphaFold DB , UniProt , Accession A0A087WPJ2, Species MOUSE (Mus musculus, Mouse), Gene Kcnq1, Length 49 aa.

>A0A087WPJ2_MOUSE|A0A087WPJ2|Kcnq1
MRGLGCPFLPPAPSLGPGTMHQLPTSILIPKNMPGGFLIVLVCLIFSVL
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40Very low49.9Very low246 Ų246148.3 Ų148.3100%1.21285%0.845SS**  0132.60-68.8167.363.100107.7
2R44.4Very low50.7Low247 Ų247143 Ų14393%0.93283%0.833SS**  trans-82.9150.8-164.3-59.7164.494.7155.83.5111.7
3G45.2Very low51.2Low73 Ų73140.1 Ų140.175%0.75382%0.821SS**  trans151.269.8165.300000111.2
4L53.6Low52Low168 Ų168138.4 Ų138.488%0.8882%0.821SS**  55.9103.784.2-69.3175.6000115.7
5G46.8Very low52.5Low74 Ų74136.8 Ų136.876%0.76381%0.806SS**  trans75.8138.4143.400000117.5
6C47.9Very low53.3Low107 Ų107130.2 Ų130.272%0.72378%0.776SS**  cis-156.3150.39.1-700000108.3
7P57.4Low53.4Low123 Ų123130.9 Ų130.980%0.79978%0.784SS**SBendtrans-75.1147.9162.933.4-29000108.6
8F56.2Low53.9Low205 Ų205128.4 Ų128.490%0.89979%0.79SS**  trans82.952.8163.6-139.8-90.8000119
9L50.5Low54.3Low149 Ų149126.5 Ų126.578%0.7878%0.778SS**  trans-112.7130.8158.1-95.481.7000110.5
10P50.7Low54.5Low110 Ų110129.6 Ų129.671%0.71479%0.786SS**PPolyproline II helixtrans-59.6145.9171.426.3-32.6000109.6A12P10-A12 PolarHBondContact O-N 2.86Å
11P56.3Low54.7Low129 Ų129128.6 Ų128.684%0.83877%0.772SS**PPolyproline II helixtrans-57.3119.1-177.722.6-31.6000109.5
12A60Low55.5Low85 Ų85125.6 Ų125.670%0.70276%0.755SS**PPolyproline II helixtrans-57.1138167.700000108P10 S14P10-A12 PolarHBondContact O-N 2.86Å; A12-S14 PolarHBondContact O-N 3Å
13P56.9Low56.5Low105 Ų105119.4 Ų119.468%0.68274%0.74SS**  trans-61.9107.3-179.624.8-31.5000108.3L15P13-L15 PolarHBondContact O-N 3.37Å
14S61.8Low57.1Low116 Ų116121.5 Ų121.581%0.81174%0.741SS**  trans-69.796.6176.257.30000108.2A12 G16A12-S14 PolarHBondContact O-N 3Å; S14-G16 PolarHBondContact O-N 3.13Å
15L59.9Low57.6Low115 Ų115119.2 Ų119.260%0.60273%0.734SS**  trans-6797169.2-69.3160.6000107.5P13 H21P13-L15 PolarHBondContact O-N 3.37Å; L15-H21 HydrophobicContact CD2-CB 3.27Å; L15-H21 WeakPolarHBondContact CD2-ND1 3.48Å
16G65.6Low58.3Low31 Ų31120.8 Ų120.832%0.3273%0.733SS.*  trans-64.3145177.900000111.3S14 G18 T19S14-G16 PolarHBondContact O-N 3.13Å; G16-G18 PolarHBondContact O-N 3.42Å; G16-T19 WeakPolarHBondContact O-CB 3.5Å; G16-T19 PolarHBondContact O-N 3.39Å; G16-T19 VanDerWaalsContact O-N 3.08Å; G16-T19 PolarHBondContact O-OG1 2.89Å
17P53.9Low59.3Low142 Ų142121.5 Ų121.592%0.92273%0.728SS**THydrogen-bonded Turntrans-56.1125.7176.1-19.529.6000110.6
18G63.4Low59.7Low87 Ų87123.3 Ų123.390%0.89773%0.731SS**THydrogen-bonded Turntrans93.80.1-17800000115.5G16G16-G18 PolarHBondContact O-N 3.42Å
19T61.9Low60.2Low91 Ų91118.4 Ų118.456%0.55871%0.712SS**  trans-92.3109.7177-300000110.4G16 H21G16-T19 WeakPolarHBondContact O-CB 3.5Å; G16-T19 PolarHBondContact O-N 3.39Å; G16-T19 VanDerWaalsContact O-N 3.08Å; G16-T19 PolarHBondContact O-OG1 2.89Å; T19-H21 PolarHBondContact O-N 3.06Å
20M57.6Low60.7Low189 Ų189115 Ų11593%0.93170%0.699SS**  trans-75104.5167.7-73.1-140.3-69.800109.3Q22M20-Q22 PolarHBondContact O-N 3.42Å
21H59.3Low61.4Low108 Ų108119.7 Ų119.750%0.571%0.708SS.*  trans-89.498.3177.5-163.6109000109.4L15 T19 L23L15-H21 HydrophobicContact CD2-CB 3.27Å; L15-H21 WeakPolarHBondContact CD2-ND1 3.48Å; T19-H21 PolarHBondContact O-N 3.06Å; H21-L23 WeakPolarHBondContact CD2-CD1 3.34Å; H21-L23 WeakPolarHBondContact NE2-CD1 3.46Å; H21-L23 PolarHBondContact O-N 2.93Å; H21-L23 VanDerWaalsContact O-N 3.15Å
22Q56.5Low61.8Low183 Ų183121 Ų12186%0.85571%0.708SS**  trans-79.796.9173.8-169.6172.7-43.900108.5M20 P24M20-Q22 PolarHBondContact O-N 3.42Å; Q22-P24 VanDerWaalsContact O-CD 3.24Å; Q22-P24 WeakPolarHBondContact O-CD 3.48Å
23L65.9Low61.9Low118 Ų118120 Ų12062%0.61869%0.69SS**  trans-73.5114.3173.7-141.974.6000107.7H21 T25H21-L23 WeakPolarHBondContact CD2-CD1 3.34Å; H21-L23 WeakPolarHBondContact NE2-CD1 3.46Å; H21-L23 PolarHBondContact O-N 2.93Å; H21-L23 VanDerWaalsContact O-N 3.15Å; L23-T25 PolarHBondContact O-N 3.25Å
24P56.1Low62.5Low117 Ų117120 Ų12076%0.7669%0.69SS**  trans-69.298.8176.727.7-32000108.7Q22 S26Q22-P24 VanDerWaalsContact O-CD 3.24Å; Q22-P24 WeakPolarHBondContact O-CD 3.48Å; P24-S26 PolarHBondContact O-N 3.48Å
25T64.6Low62.7Low119 Ų119117.2 Ų117.273%0.7368%0.68SS**  trans-78.387.8172.653.80000108.6L23L23-T25 PolarHBondContact O-N 3.25Å
26S62.6Low63.1Low107 Ų107113.8 Ų113.875%0.74867%0.672SS**  trans-88116.5167.4-175.20000108.8P24P24-S26 PolarHBondContact O-N 3.48Å
27I67.3Low63.2Low123 Ų123117.3 Ų117.363%0.63168%0.679SS**  trans-106.4115.7173.4-58.7169.5000106.6I29I27-I29 PolarHBondContact O-N 2.93Å
28L66.1Low64Low161 Ų161114.4 Ų114.484%0.84366%0.655SS**  trans-70.5113168.8-67.2173.2000107.7P30L28-P30 WeakPolarHBondContact O-CD 3.48Å
29I67.3Low64.6Low101 Ų101115.6 Ų115.652%0.51864%0.64SS.*  trans-87.2113.1176.2-56.4171.1000107.6I27 K31 M33 L38I27-I29 PolarHBondContact O-N 2.93Å; I29-K31 PolarHBondContact O-N 3.29Å; I29-M33 HydrophobicContact CG2-SD 3.93Å; I29-L38 HydrophobicContact CD1-CD2 4.08Å; I29-L38 HydrophobicContact CG2-CD2 4.37Å
30P61.1Low65.4Low77 Ų77115.9 Ų115.950%0.564%0.641SS.*  trans-54.4129.4174.4-8.84.2000111.2L28 N32 M33L28-P30 WeakPolarHBondContact O-CD 3.48Å; P30-N32 PolarHBondContact O-N 3.31Å; P30-M33 HydrophobicContact CB-CG 3.89Å; P30-M33 HydrophobicContact CB-SD 4.43Å; P30-M33 WeakPolarHBondContact CD-SD 3.32Å; P30-M33 HydrophobicContact CG-CE 4.45Å; P30-M33 HydrophobicContact CG-CG 3.69Å; P30-M33 HydrophobicContact CG-SD 3.69Å; P30-M33 WeakPolarHBondContact O-CG 3.18Å; P30-M33 PolarHBondContact O-N 3.43Å; P30-M33 VanDerWaalsContact O-N 3.13Å
31K64.9Low66.4Low209 Ų209109.7 Ų109.791%0.90961%0.612SS**THydrogen-bonded Turntrans-57.6-12.9-177-155.9-170.679.271.30114.5I29I29-K31 PolarHBondContact O-N 3.29Å
32N64.6Low67.4Low156 Ų156109.1 Ų109.183%0.83462%0.615SS**THydrogen-bonded Turntrans-121.532-176.8-156.953.9000112.5P30P30-N32 PolarHBondContact O-N 3.31Å
33M62.6Low68.5Low65 Ų65103.7 Ų103.732%0.3260%0.597SS.*  trans-76.9135.4169.9-72.1-177105.900110.2I29 P30 G35 F37I29-M33 HydrophobicContact CG2-SD 3.93Å; P30-M33 HydrophobicContact CB-CG 3.89Å; P30-M33 HydrophobicContact CB-SD 4.43Å; P30-M33 WeakPolarHBondContact CD-SD 3.32Å; P30-M33 HydrophobicContact CG-CE 4.45Å; P30-M33 HydrophobicContact CG-CG 3.69Å; P30-M33 HydrophobicContact CG-SD 3.69Å; P30-M33 WeakPolarHBondContact O-CG 3.18Å; P30-M33 PolarHBondContact O-N 3.43Å; P30-M33 VanDerWaalsContact O-N 3.13Å; M33-G35 PolarHBondContact O-N 3.27Å; M33-F37 HydrophobicContact CE-CB 4.31Å; M33-F37 HydrophobicContact CE-CD1 3.31Å; M33-F37 HydrophobicContact CE-CD2 3.9Å; M33-F37 HydrophobicContact CE-CE1 3.43Å; M33-F37 VanDerWaalsContact CE-CE1 3.43Å; M33-F37 HydrophobicContact CE-CE2 4Å; M33-F37 HydrophobicContact CE-CG 3.56Å; M33-F37 HydrophobicContact CE-CZ 3.78Å; M33-F37 HydrophobicContact SD-CD1 3.91Å; M33-F37 HydrophobicContact SD-CE1 4.29Å; M33-F37 HydrophobicContact SD-CG 4.43Å
34P69.3Low69.1Low104 Ų104103.2 Ų103.268%0.67559%0.594SS**  trans-58.2133.9172.824.7-32.2000109.2G36 F37P34-G36 PolarHBondContact O-N 3.5Å; P34-F37 PolarHBondContact O-N 3.48Å
35G65.1Low70.3Confident59 Ų59101.9 Ų101.961%0.60858%0.58SS**THydrogen-bonded Turntrans-56.3-15.2-170.700000115.7M33 F37M33-G35 PolarHBondContact O-N 3.27Å; G35-F37 VanDerWaalsContact C-N 3.34Å; G35-F37 PolarHBondContact O-N 3.34Å
36G70Confident70.9Confident43 Ų43103.8 Ų103.844%0.44358%0.579SS.*Hα-helixtrans-70.2-21.8174.500000115P34 L38 I39 V40P34-G36 PolarHBondContact O-N 3.5Å; G36-L38 VanDerWaalsContact C-N 3.34Å; G36-L38 PolarHBondContact O-N 3.29Å; G36-I39 PolarHBondContact O-N 2.73Å; G36-V40 WeakPolarHBondContact O-CG2 3.28Å; G36-V40 PolarHBondContact O-N 3.37Å
37F67.8Low71.3Confident104 Ų104103.4 Ų103.446%0.45658%0.576SS.*Hα-helixtrans-67-35.6-177.5-170.9-94.4000112.6M33 P34 G35 I39 V40 L41M33-F37 HydrophobicContact CE-CB 4.31Å; M33-F37 HydrophobicContact CE-CD1 3.31Å; M33-F37 HydrophobicContact CE-CD2 3.9Å; M33-F37 HydrophobicContact CE-CE1 3.43Å; M33-F37 VanDerWaalsContact CE-CE1 3.43Å; M33-F37 HydrophobicContact CE-CE2 4Å; M33-F37 HydrophobicContact CE-CG 3.56Å; M33-F37 HydrophobicContact CE-CZ 3.78Å; M33-F37 HydrophobicContact SD-CD1 3.91Å; M33-F37 HydrophobicContact SD-CE1 4.29Å; M33-F37 HydrophobicContact SD-CG 4.43Å; P34-F37 PolarHBondContact O-N 3.48Å; G35-F37 VanDerWaalsContact C-N 3.34Å; G35-F37 PolarHBondContact O-N 3.34Å; F37-I39 VanDerWaalsContact C-N 3.34Å; F37-V40 PolarHBondContact O-N 3.32Å; F37-L41 WeakPolarHBondContact O-CB 3.36Å; F37-L41 PolarHBondContact O-N 3.43Å
38L69.6Low71.3Confident82 Ų82103.4 Ų103.443%0.42958%0.581SS.*Hα-helixtrans-67.8-35.7177.8-63.5178.6000112I29 G36 L41 V42I29-L38 HydrophobicContact CD1-CD2 4.08Å; I29-L38 HydrophobicContact CG2-CD2 4.37Å; G36-L38 VanDerWaalsContact C-N 3.34Å; G36-L38 PolarHBondContact O-N 3.29Å; L38-L41 PolarHBondContact O-N 3.35Å; L38-V42 VanDerWaalsContact O-CG2 3.31Å; L38-V42 WeakPolarHBondContact O-CG2 3.49Å; L38-V42 PolarHBondContact O-N 2.98Å
39I76.9Confident71.1Confident112 Ų112104.7 Ų104.757%0.57459%0.588SS**Hα-helixtrans-66.1-46.3178.5-58174.1000109.9G36 F37 L41 V42 C43G36-I39 PolarHBondContact O-N 2.73Å; F37-I39 VanDerWaalsContact C-N 3.34Å; I39-L41 VanDerWaalsContact C-N 3.31Å; I39-L41 PolarHBondContact O-N 2.97Å; I39-V42 PolarHBondContact O-N 2.96Å; I39-C43 WeakPolarHBondContact O-CB 3.47Å; I39-C43 PolarHBondContact O-N 3.42Å; I39-C43 PolarHBondContact O-SG 3.23Å; I39-C43 VanDerWaalsContact O-SG 3.32Å
40V77.4Confident71.3Confident96 Ų96104.9 Ų104.958%0.58259%0.592SS**Hα-helixtrans-61.1-41.6177177.20000111.1G36 F37 C43 L44G36-V40 WeakPolarHBondContact O-CG2 3.28Å; G36-V40 PolarHBondContact O-N 3.37Å; F37-V40 PolarHBondContact O-N 3.32Å; V40-C43 PolarHBondContact O-N 3.37Å; V40-L44 WeakPolarHBondContact O-CB 3.38Å; V40-L44 PolarHBondContact O-N 3.01Å
41L78.8Confident71.9Confident59 Ų59106.4 Ų106.431%0.30960%0.597SS.*Hα-helixtrans-62.1-45.3177.2-175.564.9000112F37 L38 I39 L44 I45F37-L41 WeakPolarHBondContact O-CB 3.36Å; F37-L41 PolarHBondContact O-N 3.43Å; L38-L41 PolarHBondContact O-N 3.35Å; I39-L41 VanDerWaalsContact C-N 3.31Å; I39-L41 PolarHBondContact O-N 2.97Å; L41-L44 PolarHBondContact O-N 2.9Å; L41-I45 HydrophobicContact CD1-CD1 4.34Å; L41-I45 HydrophobicContact CG-CD1 4.05Å; L41-I45 WeakPolarHBondContact O-CD1 3.31Å; L41-I45 VanDerWaalsContact O-CG1 3.28Å; L41-I45 WeakPolarHBondContact O-CG1 3.24Å; L41-I45 PolarHBondContact O-N 3.05Å
42V80.3Confident72.2Confident96 Ų96100.7 Ų100.758%0.58258%0.579SS**Hα-helixtrans-64.4-44.1177.4171.20000111.3L38 I39 L44 I45 F46L38-V42 VanDerWaalsContact O-CG2 3.31Å; L38-V42 WeakPolarHBondContact O-CG2 3.49Å; L38-V42 PolarHBondContact O-N 2.98Å; I39-V42 PolarHBondContact O-N 2.96Å; V42-L44 VanDerWaalsContact C-N 3.31Å; V42-L44 PolarHBondContact O-N 3.06Å; V42-I45 PolarHBondContact O-N 2.94Å; V42-F46 WeakPolarHBondContact O-CB 3.49Å; V42-F46 PolarHBondContact O-N 3.24Å
43C80.6Confident72.7Confident69 Ų6997.4 Ų97.447%0.46656%0.564SS.*Hα-helixtrans-61.3-39.8176.2-71.40000112.2I39 V40 S47I39-C43 WeakPolarHBondContact O-CB 3.47Å; I39-C43 PolarHBondContact O-N 3.42Å; I39-C43 PolarHBondContact O-SG 3.23Å; I39-C43 VanDerWaalsContact O-SG 3.32Å; V40-C43 PolarHBondContact O-N 3.37Å; C43-S47 WeakPolarHBondContact O-CB 3.24Å; C43-S47 PolarHBondContact O-N 3.15Å; C43-S47 PolarHBondContact O-OG 3.01Å
44L78.8Confident73.3Confident108 Ų10899.4 Ų99.457%0.56558%0.579SS**Hα-helixtrans-67.4-43178.6-171126.8000111.6V40 L41 V42 S47 V48V40-L44 WeakPolarHBondContact O-CB 3.38Å; V40-L44 PolarHBondContact O-N 3.01Å; L41-L44 PolarHBondContact O-N 2.9Å; V42-L44 VanDerWaalsContact C-N 3.31Å; V42-L44 PolarHBondContact O-N 3.06Å; L44-S47 PolarHBondContact O-N 2.87Å; L44-V48 VanDerWaalsContact O-CG2 3.32Å; L44-V48 WeakPolarHBondContact O-CG2 3.42Å; L44-V48 PolarHBondContact O-N 3.2Å
45I80.5Confident73.6Confident89 Ų8999.1 Ų99.146%0.45657%0.573SS.*Hα-helixtrans-62.1-46.9176-67.3163.3000110.6L41 V42 S47 V48 L49L41-I45 HydrophobicContact CD1-CD1 4.34Å; L41-I45 HydrophobicContact CG-CD1 4.05Å; L41-I45 WeakPolarHBondContact O-CD1 3.31Å; L41-I45 VanDerWaalsContact O-CG1 3.28Å; L41-I45 WeakPolarHBondContact O-CG1 3.24Å; L41-I45 PolarHBondContact O-N 3.05Å; V42-I45 PolarHBondContact O-N 2.94Å; I45-S47 VanDerWaalsContact C-N 3.31Å; I45-S47 PolarHBondContact O-N 2.77Å; I45-V48 PolarHBondContact O-N 3.4Å; I45-L49 HydrophobicContact CG2-CD1 3.9Å; I45-L49 PolarHBondContact O-N 3.08Å
46F76.5Confident74.2Confident160 Ų160102 Ų10270%0.70257%0.571SS**Hα-helixtrans-67.9-29.1180-170.1-95.4000113.2V42 V48V42-F46 WeakPolarHBondContact O-CB 3.49Å; V42-F46 PolarHBondContact O-N 3.24Å; F46-V48 VanDerWaalsContact C-N 3.29Å; F46-V48 PolarHBondContact O-N 3.24Å
47S72.5Confident74.5Confident99 Ų99106.5 Ų106.569%0.69258%0.58SS**Hα-helixtrans-75.3-18.8177.6-58.50000113.5C43 L44 I45C43-S47 WeakPolarHBondContact O-CB 3.24Å; C43-S47 PolarHBondContact O-N 3.15Å; C43-S47 PolarHBondContact O-OG 3.01Å; L44-S47 PolarHBondContact O-N 2.87Å; I45-S47 VanDerWaalsContact C-N 3.31Å; I45-S47 PolarHBondContact O-N 2.77Å
48V67.8Low75.1Confident123 Ų123106.8 Ų106.875%0.74559%0.591SS**Hα-helixtrans-96.2-24.5-179174.90000111.9L44 I45 F46L44-V48 VanDerWaalsContact O-CG2 3.32Å; L44-V48 WeakPolarHBondContact O-CG2 3.42Å; L44-V48 PolarHBondContact O-N 3.2Å; I45-V48 PolarHBondContact O-N 3.4Å; F46-V48 VanDerWaalsContact C-N 3.29Å; F46-V48 PolarHBondContact O-N 3.24Å
49L61.5Low75.6Confident188 Ų188109 Ų10998%0.98461%0.605SS**  trans-75.80171.5-93152.1000111.5I45I45-L49 HydrophobicContact CG2-CD1 3.9Å; I45-L49 PolarHBondContact O-N 3.08Å

Retrieved 49 of 49 residues in 106.3 ms (Link to these results)