A0A087WQE3_MOUSE Loading...

Potassium voltage-gated channel, subfamily Q, member 1

AlphaFold DB , UniProt , Accession A0A087WQE3, Species MOUSE (Mus musculus, Mouse), Gene Kcnq1, Length 77 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M28.7Very low50.7Low245 Ų245155.2 Ų155.2100%1.20779%0.794SS**  0144.50-85.8178.1161.500109
2P52.5Low51.4Low110 Ų110157.8 Ų157.871%0.71480%0.795SS**  trans-84.8171.1-155.137.3-34.7000112.2
3L55.2Low51.9Low163 Ų163153.4 Ų153.485%0.85379%0.788SS**  -160.1126.3100.1-86.3162.3000110.5
4R54.5Low52.7Low221 Ų221154.9 Ų154.983%0.83479%0.79SS**  trans-60.4-179.9162.4-80175.3163177.7-5.4111.2
5H52.7Low53.2Low149 Ų149154.5 Ų154.569%0.6978%0.781SS**  trans101.498.2170.5-55.3-71.1000110.8
6S46.4Very low53.6Low109 Ų109148.3 Ų148.376%0.76277%0.767SS**  3499.752.6-171.20000112.1
7K58Low53.7Low165 Ų165153.8 Ų153.872%0.71778%0.776SS**  trans-174.4123.8137.7-97.7155.5-171.4-171.20111
8N55.3Low54Low140 Ų140152.9 Ų152.975%0.74977%0.773SS**  trans6681.7134.3-61.7-6.3000117.4A10N8-A10 PolarHBondContact O-N 3.06Å
9Q46.5Very low54.2Low165 Ų165153.3 Ų153.377%0.77177%0.769SS**  -190.7112.6-161.9178.742.200113.8H11Q9-H11 PolarHBondContact NE2-NE2 2.96Å
10A56.6Low54.3Low88 Ų88150 Ų15073%0.72777%0.767SS**  trans-91.996.8160.100000106.6N8 K12N8-A10 PolarHBondContact O-N 3.06Å; A10-K12 PolarHBondContact O-N 3.01Å; A10-K12 VanDerWaalsContact C-N 3.35Å
11H51.2Low54.3Low152 Ų152150.9 Ų150.970%0.70477%0.773SS**  trans-60.9100.6163.7-84.7-85.3000107.6Q9 S13Q9-H11 PolarHBondContact NE2-NE2 2.96Å; H11-S13 VanDerWaalsContact C-N 3.3Å; H11-S13 PolarHBondContact O-N 3.19Å
12K59.6Low55.6Low186 Ų186146 Ų14681%0.80975%0.747SS**  trans-70.596162.7-75.5-177.5178.9-179.30106.2A10 E14A10-K12 PolarHBondContact O-N 3.01Å; A10-K12 VanDerWaalsContact C-N 3.35Å; K12-E14 PolarHBondContact O-N 3.21Å
13S57.4Low55.7Low101 Ų101152.4 Ų152.471%0.70676%0.757SS**  trans-65.6101.2169-172.40000108.1H11 F15H11-S13 VanDerWaalsContact C-N 3.3Å; H11-S13 PolarHBondContact O-N 3.19Å; S13-F15 PolarHBondContact O-N 3.05Å
14E63.5Low55.5Low174 Ų174153.2 Ų153.281%0.81376%0.756SS**G310 helixtrans-76.212.4177.1-68.4-177.9133.100112.9K12K12-E14 PolarHBondContact O-N 3.21Å
15F59.4Low55.6Low149 Ų149148.4 Ų148.465%0.65475%0.752SS**G310 helixtrans-89.61.5-178.2-108.7-92.2000114.9S13S13-F15 PolarHBondContact O-N 3.05Å
16G59.8Low55.7Low55 Ų55148.7 Ų148.757%0.56776%0.757SS**G310 helixtrans-83.2-5.3-178.600000116
17W56.3Low56.1Low243 Ų243148 Ų14892%0.9276%0.758SS**SBendtrans-101.1-9-174.1-67.10000114.7
18L58.8Low56Low138 Ų138148.6 Ų148.672%0.72376%0.763SS**SBendtrans-89.8-7.8-177.4-77.3166.8000114.8
19F57Low55.7Low159 Ų159145.4 Ų145.470%0.69776%0.763SS**SBendtrans-1115-176.2-70.3-82.2000114.8
20A57.4Low56.3Low88 Ų88145.3 Ų145.373%0.72777%0.766SS**SBendtrans-91.810.4-176.100000115
21L53.9Low56Low168 Ų168150.4 Ų150.488%0.8878%0.775SS**SBendtrans-135.436.5-172.2-116.1152000113.8
22Q55.3Low56Low144 Ų144146.7 Ų146.767%0.67378%0.777SS**SBendtrans-130.916.9-172.3-143.5-177.38.900116.4
23R54.5Low55.7Low244 Ų244147.5 Ų147.592%0.92178%0.781SS**SBendtrans-134.323.9-177.3-76.9-163.6168.8-175.1-2.4117.9
24E52.3Low55.5Low179 Ų179147.8 Ų147.884%0.83678%0.783SS**SBendtrans-124.6-10.8168.9-75.2-170.2141.600115.5
25T55.2Low55.2Low120 Ų120147.9 Ų147.974%0.73679%0.788SS**THydrogen-bonded Turntrans-91.30.5-175.824.80000116.2
26I55.1Low55.3Low155 Ų155147.5 Ų147.580%0.79579%0.793SS**THydrogen-bonded Turntrans-85.2-15.1-179.3-63.8172.6000112.4
27A55.9Low55.2Low95 Ų95151.1 Ų151.179%0.78580%0.804SS**SBendtrans-98.21.1-17100000116.1
28Q54.1Low55.4Low178 Ų178147.8 Ų147.883%0.83280%0.803SS**SBendtrans-115.87.3-172.8-73-172.2-24.700115.7
29G49.2Very low54.9Low73 Ų73145.7 Ų145.775%0.75380%0.8SS**SBendtrans-953.8-177.600000116.9
30I58.8Low54.8Low163 Ų163143.1 Ų143.184%0.83680%0.8SS**SBendtrans-12651.5-175-42176.1000111
31Q51.7Low54.8Low195 Ų195146.7 Ų146.791%0.91181%0.806SS**  trans-150.188.8161.9-76.7-158.8500110.2
32G50.2Low55.1Low73 Ų73142.2 Ų142.275%0.75379%0.793SS**  trans-168.955.3-178.500000113.7
33K54.4Low55.4Low204 Ų204145 Ų14589%0.88780%0.803SS**  trans23.3109.8146.2-60.7177.4177.7178.40117.6
34S52.6Low55.7Low107 Ų107140.5 Ų140.575%0.74880%0.797SS**  172110.7108.944.60000109.3D36S34-D36 PolarHBondContact O-N 3.13Å; S34-D36 VanDerWaalsContact O-N 3.14Å
35L57.2Low55.7Low175 Ų175137 Ų13792%0.91679%0.789SS**  trans-82.753.9173.2-168.791.2000108.6
36D60.8Low55.6Low141 Ų141139.5 Ų139.575%0.75479%0.785SS**  trans-153.855.9-175.3-80.6-59.9000112.1S34S34-D36 PolarHBondContact O-N 3.13Å; S34-D36 VanDerWaalsContact O-N 3.14Å
37T58.4Low55.6Low131 Ų131138.2 Ų138.280%0.80478%0.78SS**  trans-154.573.2144.4-310000108.7S39T37-S39 PolarHBondContact O-N 2.86Å
38L59.6Low55.6Low173 Ų173138.7 Ų138.791%0.90677%0.77SS**  trans-60.886.5153.6-82.2157.4000107.1P40L38-P40 VanDerWaalsContact O-CD 3.31Å; L38-P40 WeakPolarHBondContact O-CD 3.31Å
39S48.4Very low55.7Low94 Ų94134.4 Ų134.466%0.65776%0.764SS**  trans-77.6110.8151.2-172.30000104.9T37 L41T37-S39 PolarHBondContact O-N 2.86Å; S39-L41 PolarHBondContact O-N 3.14Å
40P55.4Low56.1Low106 Ų106135.9 Ų135.969%0.68876%0.763SS**  trans-67.194.4168.429.9-28.6000104.4L38 A42L38-P40 VanDerWaalsContact O-CD 3.31Å; L38-P40 WeakPolarHBondContact O-CD 3.31Å; P40-A42 PolarHBondContact O-N 2.8Å
41L58.1Low55.8Low163 Ų163130 Ų13085%0.85374%0.739SS**  trans-53.2103154.1-109.2153.4000103.5S39 F43S39-L41 PolarHBondContact O-N 3.14Å; L41-F43 PolarHBondContact O-N 3.1Å; L41-F43 VanDerWaalsContact O-N 3.07Å
42A60.2Low55.9Low74 Ų74125.6 Ų125.661%0.61273%0.727SS**  trans-46.4121.9-169.700000107.2P40 L44P40-A42 PolarHBondContact O-N 2.8Å; A42-L44 PolarHBondContact O-N 3.07Å
43F60.8Low56.2Low203 Ų203129.3 Ų129.389%0.8973%0.725SS**  trans-56.292.9156.6-76.6-94.7000104.7L41 P45L41-F43 PolarHBondContact O-N 3.1Å; L41-F43 VanDerWaalsContact O-N 3.07Å; F43-P45 VanDerWaalsContact O-CD 3.22Å; F43-P45 WeakPolarHBondContact O-CD 3.47Å; F43-P45 VanDerWaalsContact O-N 3.15Å
44L61.4Low56.5Low148 Ų148127.5 Ų127.578%0.77572%0.717SS**  trans-57.3118.5159.8-74.5165.7000103.4A42 W46A42-L44 PolarHBondContact O-N 3.07Å; L44-W46 PolarHBondContact O-N 2.77Å
45P52.8Low56.8Low105 Ų105132.8 Ų132.868%0.68272%0.722SS**  trans-58.5104.5160.826.2-29.1000103.7F43 D47F43-P45 VanDerWaalsContact O-CD 3.22Å; F43-P45 WeakPolarHBondContact O-CD 3.47Å; F43-P45 VanDerWaalsContact O-N 3.15Å; P45-D47 PolarHBondContact O-N 2.73Å
46W52.9Low57Low173 Ų173127.5 Ų127.566%0.65570%0.7SS**  trans-65.697.1161.5108-68.3000102.7L44 N48 A51L44-W46 PolarHBondContact O-N 2.77Å; W46-N48 HydrophobicContact CD2-CB 4.31Å; W46-N48 VanDerWaalsContact CE2-CG 3.47Å; W46-N48 WeakPolarHBondContact CH2-OD1 3.22Å; W46-N48 HydrophobicContact CZ2-CB 3.85Å; W46-N48 WeakPolarHBondContact CZ2-OD1 3.25Å; W46-N48 PolarHBondContact O-N 2.7Å; W46-A51 HydrophobicContact CH2-CB 4.15Å; W46-A51 HydrophobicContact CZ3-CB 3.99Å
47D54.6Low56.9Low129 Ų129125.4 Ų125.469%0.6969%0.689SS**  trans-59.4103.5163.3-91.7-55000104.7P45 A49P45-D47 PolarHBondContact O-N 2.73Å; D47-A49 PolarHBondContact O-N 3.38Å
48N55.7Low56.8Low105 Ų105124.6 Ų124.656%0.56169%0.686SS**THydrogen-bonded Turntrans-70.143.8179.9-163.93.3000110.6W46W46-N48 HydrophobicContact CD2-CB 4.31Å; W46-N48 VanDerWaalsContact CE2-CG 3.47Å; W46-N48 WeakPolarHBondContact CH2-OD1 3.22Å; W46-N48 HydrophobicContact CZ2-CB 3.85Å; W46-N48 WeakPolarHBondContact CZ2-OD1 3.25Å; W46-N48 PolarHBondContact O-N 2.7Å
49A56.1Low56.6Low87 Ų87124.1 Ų124.172%0.71968%0.679SS**THydrogen-bonded Turntrans-126.55.7-177.200000111.9D47D47-A49 PolarHBondContact O-N 3.38Å
50S58Low56.8Low105 Ų105124.5 Ų124.573%0.73467%0.671SS**  trans-140.824.3-178.7-47.60000113.8P52S50-P52 VanDerWaalsContact O-CD 3.25Å; S50-P52 WeakPolarHBondContact O-CD 2.81Å
51A51.7Low56.6Low40 Ų40125.6 Ų125.633%0.33167%0.666SS.*  trans-80.7112.5155.900000107.3W46 H53W46-A51 HydrophobicContact CH2-CB 4.15Å; W46-A51 HydrophobicContact CZ3-CB 3.99Å; A51-H53 VanDerWaalsContact C-N 3.33Å; A51-H53 PolarHBondContact O-CD2 3.04Å; A51-H53 PolarHBondContact O-N 3.12Å
52P54.7Low56.4Low101 Ų101121.3 Ų121.366%0.65665%0.654SS**  trans-65.7103.1166.328.5-31.3000106.3S50 F54S50-P52 VanDerWaalsContact O-CD 3.25Å; S50-P52 WeakPolarHBondContact O-CD 2.81Å; P52-F54 HydrophobicContact CB-CD2 3.92Å; P52-F54 HydrophobicContact CB-CE2 4.12Å; P52-F54 HydrophobicContact CG-CD2 4.45Å; P52-F54 PolarHBondContact O-N 3.04Å
53H57.1Low56.2Low151 Ų151128.6 Ų128.670%0.69967%0.666SS**  trans-63.281.7170.2-75.8-96.1000108.3A51 Y55A51-H53 VanDerWaalsContact C-N 3.33Å; A51-H53 PolarHBondContact O-CD2 3.04Å; A51-H53 PolarHBondContact O-N 3.12Å; H53-Y55 PolarHBondContact O-N 3.25Å
54F59.6Low56Low166 Ų166127.3 Ų127.373%0.72866%0.655SS**  trans-79.264.5165.4-91.8-87.4000108.9P52P52-F54 HydrophobicContact CB-CD2 3.92Å; P52-F54 HydrophobicContact CB-CE2 4.12Å; P52-F54 HydrophobicContact CG-CD2 4.45Å; P52-F54 PolarHBondContact O-N 3.04Å
55Y60.4Low55.8Low218 Ų218125.9 Ų125.986%0.85565%0.647SS**  trans-102.269.8152.1-75.4-84.2000106.4H53 D57H53-Y55 PolarHBondContact O-N 3.25Å; Y55-D57 PolarHBondContact O-N 3.28Å
56S59.5Low55.8Low65 Ų65126.2 Ų126.246%0.45565%0.649SS.*  trans-72.9112.5166.950.40000107.7
57D58.7Low56Low97 Ų97126 Ų12652%0.51966%0.655SS.*  trans-42.1131.2169.7-160.8-36.6000110.3Y55 Q59 E60Y55-D57 PolarHBondContact O-N 3.28Å; D57-Q59 PolarHBondContact O-N 2.85Å; D57-Q59 PolarHBondContact OD1-N 2.8Å; D57-E60 PolarHBondContact O-N 2.77Å
58P56.6Low56.1Low114 Ų114126 Ų12674%0.7467%0.665SS**Hα-helixtrans-54.9-19.5178.517.7-30000113.7
59Q55.1Low56.4Low162 Ų162126.2 Ų126.276%0.75767%0.674SS**Hα-helixtrans-74.4-27171.4-81.4-154-2100115.1D57D57-Q59 PolarHBondContact O-N 2.85Å; D57-Q59 PolarHBondContact OD1-N 2.8Å
60E54.3Low56.3Low103 Ų103125.3 Ų125.348%0.48167%0.673SS.*Hα-helixtrans-75.9-27.1178.6-92.7-132130.600112.6D57 A62 R63 R64D57-E60 PolarHBondContact O-N 2.77Å; E60-A62 VanDerWaalsContact C-N 3.33Å; E60-A62 PolarHBondContact O-N 2.75Å; E60-R63 PolarHBondContact O-N 3.43Å; E60-R64 IonicContact OE2-NH2 3.96Å
61H50.4Low56.1Low129 Ų129126.8 Ų126.860%0.59767%0.672SS**Hα-helixtrans-67.4-34.2178.4-165.974.8000112.2R63 R64H61-R63 PolarHBondContact O-N 2.87Å; H61-R64 PolarHBondContact O-N 2.9Å; H61-R64 VanDerWaalsContact O-N 3.12Å
62A54.7Low56.3Low72 Ų72131 Ų13160%0.59570%0.696SS**G310 helixtrans-65.9-22.9178.700000113.4E60E60-A62 VanDerWaalsContact C-N 3.33Å; E60-A62 PolarHBondContact O-N 2.75Å
63R55.7Low56.4Low228 Ų228133.6 Ų133.686%0.8670%0.699SS**G310 helixtrans-84.2-10.1175.8-90.5-178.2166.5162.2-2.1114.2E60 H61E60-R63 PolarHBondContact O-N 3.43Å; H61-R63 PolarHBondContact O-N 2.87Å
64R56.4Low56.2Low176 Ų176133.2 Ų133.266%0.66470%0.701SS**G310 helixtrans-105.411.5178.8-64.1-172.3-172.7178.36.3113.3E60 H61 P66E60-R64 IonicContact OE2-NH2 3.96Å; H61-R64 PolarHBondContact O-N 2.9Å; H61-R64 VanDerWaalsContact O-N 3.12Å; R64-P66 WeakPolarHBondContact O-CD 3.1Å
65L56Low55.9Low117 Ų117133.3 Ų133.361%0.61370%0.704SS**SBendtrans-75.2120.9162.3-75.4165.6000107.1H67L65-H67 PolarHBondContact O-N 3.29Å
66P54.6Low55.3Low112 Ų112128.3 Ų128.373%0.72770%0.7SS**  trans-57121.9170.824.6-30.7000106.5R64 C68R64-P66 WeakPolarHBondContact O-CD 3.1Å; P66-C68 PolarHBondContact O-N 2.98Å
67H55.8Low54.8Low168 Ų168134.8 Ų134.878%0.77874%0.74SS**  trans-41.3120.9164.7-75.8-96.2000107.1L65 S69L65-H67 PolarHBondContact O-N 3.29Å; H67-S69 PolarHBondContact O-N 3.34Å; H67-S69 PolarHBondContact O-OG 3.47Å
68C57.9Low54.6Low131 Ų131136.7 Ų136.789%0.88575%0.751SS**  trans-6661.3160.5-72.70000108.2P66 G70P66-C68 PolarHBondContact O-N 2.98Å; C68-G70 PolarHBondContact O-N 2.87Å
69S60.2Low54.5Low109 Ų109137.9 Ų137.976%0.76275%0.752SS**  trans-82.993.1171.553.90000106.4H67H67-S69 PolarHBondContact O-N 3.34Å; H67-S69 PolarHBondContact O-OG 3.47Å
70G55.9Low54.4Low67 Ų67136.6 Ų136.669%0.69175%0.752SS**SBendtrans152.33.6162.700000120C68C68-G70 PolarHBondContact O-N 2.87Å
71L53.9Low54.4Low136 Ų136138.5 Ų138.571%0.71277%0.768SS**  trans-141.1115.3176.6-72.8171.6000111.6H73 L74L71-H73 PolarHBondContact O-N 2.96Å; L71-H73 VanDerWaalsContact O-N 3.1Å; L71-L74 HydrophobicContact CD1-CD1 4.4Å
72P54.6Low54.7Low129 Ų129139.1 Ų139.184%0.83878%0.778SS**THydrogen-bonded Turntrans-7812.6-172.230.8-34.5000115
73H56.7Low54.7Low156 Ų156143.6 Ų143.672%0.72279%0.79SS**THydrogen-bonded Turntrans-156.436.3-171.6-129-74.7000117.1L71L71-H73 PolarHBondContact O-N 2.96Å; L71-H73 VanDerWaalsContact O-N 3.1Å
74L53.6Low54.6Low142 Ų142137.6 Ų137.674%0.74379%0.785SS**  trans-104.494.8159.6-98.2107.9000109.3L71 C76L71-L74 HydrophobicContact CD1-CD1 4.4Å; L74-C76 PolarHBondContact O-N 3.37Å; L74-C76 VanDerWaalsContact O-N 3.13Å
75Q52Low54.5Low168 Ų168134.6 Ų134.679%0.78580%0.795SS**  trans-59.9107.2161.6-71.6168.3-24.900107.4
76C48.5Very low54.4Low114 Ų114136.1 Ų136.177%0.7781%0.81SS**  trans-63.7136.6161.9-610000107.8L74L74-C76 PolarHBondContact O-N 3.37Å; L74-C76 VanDerWaalsContact O-N 3.13Å
77P48.7Very low54.3Low201 Ų201138.3 Ų138.3100%1.30582%0.817SS**  trans-62.20174.128.2-34.6000112.3

Retrieved 77 of 77 residues in 186.9 ms (Link to these results)