A0A087WQN3_MOUSE Loading...

Empty spiracles homeobox 2

AlphaFold DB , UniProt , Accession A0A087WQN3, Species MOUSE (Mus musculus, Mouse), Gene Emx2, Length 69 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1S53.3Low67.9Low171 Ų171112.4 Ų112.4100%1.19667%0.668SS**  0107.10-163.40000107.8H3S1-H3 PolarHBondContact O-N 2.91Å
2S67.6Low68.3Low129 Ų129114.7 Ų114.790%0.90267%0.666SS**  trans-93.791.5-177.4-169.50000108.5S4S2-S4 PolarHBondContact O-N 3.43Å
3H66.9Low68.4Low171 Ų171121.2 Ų121.279%0.79269%0.687SS**  trans-90.392.6178.5-149.1-36.2000108.4S1S1-H3 PolarHBondContact O-N 2.91Å
4S70.4Confident68.7Low94 Ų94118.9 Ų118.966%0.65766%0.662SS**PPolyproline II helixtrans-64.1127.2165.2-175.20000107.6S2 H6S2-S4 PolarHBondContact O-N 3.43Å; S4-H6 PolarHBondContact O-N 3Å
5P74.4Confident69.3Low82 Ų82118.1 Ų118.153%0.53266%0.656SS.*PPolyproline II helixtrans-62.3128.9176.924.3-30.8000108.4
6H71.3Confident69.3Low103 Ų103115.8 Ų115.848%0.47765%0.648SS.*PPolyproline II helixtrans-52.6133.1177.7-172.2-84.3000108.2S4 L8 F9 A10S4-H6 PolarHBondContact O-N 3Å; H6-L8 WeakPolarHBondContact CE1-CD1 3.23Å; H6-L8 VanDerWaalsContact CE1-CG 3.43Å; H6-L8 WeakPolarHBondContact CE1-CG 3.38Å; H6-L8 WeakPolarHBondContact ND1-CB 3.49Å; H6-L8 WeakPolarHBondContact ND1-CG 3.46Å; H6-L8 PolarHBondContact ND1-N 3.48Å; H6-L8 PolarHBondContact O-N 3.26Å; H6-F9 HydrophobicContact CB-CD2 4.1Å; H6-F9 PolarHBondContact O-N 3.39Å; H6-A10 PolarHBondContact O-N 3.3Å
7P70.3Confident69.2Low76 Ų76112.7 Ų112.749%0.49464%0.636SS.*G310 helixtrans-55.1-28.5-168.718.1-32.2000113.1F9 A10 R14P7-F9 VanDerWaalsContact C-N 3.29Å; P7-F9 PolarHBondContact O-N 2.81Å; P7-A10 PolarHBondContact O-N 3.19Å; P7-R14 VanDerWaalsContact O-CZ 3.31Å; P7-R14 PolarHBondContact O-NH2 3.41Å
8L70.3Confident69.3Low84 Ų84112.5 Ų112.544%0.4464%0.637SS.*G310 helixtrans-61.4-30.2174.4-61176.3000114.4H6 F19H6-L8 WeakPolarHBondContact CE1-CD1 3.23Å; H6-L8 VanDerWaalsContact CE1-CG 3.43Å; H6-L8 WeakPolarHBondContact CE1-CG 3.38Å; H6-L8 WeakPolarHBondContact ND1-CB 3.49Å; H6-L8 WeakPolarHBondContact ND1-CG 3.46Å; H6-L8 PolarHBondContact ND1-N 3.48Å; H6-L8 PolarHBondContact O-N 3.26Å; L8-F19 WeakPolarHBondContact O-CZ 3.22Å; L8-F19 HydrophobicContact CD2-CE2 3.79Å; L8-F19 HydrophobicContact CB-CZ 4.4Å; L8-F19 HydrophobicContact CB-CE2 4.33Å
9F70.1Confident69.4Low174 Ų174110.1 Ų110.176%0.76362%0.619SS**G310 helixtrans-107.20.9179.9-56.3-68.1000112.6H6 P7H6-F9 HydrophobicContact CB-CD2 4.1Å; H6-F9 PolarHBondContact O-N 3.39Å; P7-F9 VanDerWaalsContact C-N 3.29Å; P7-F9 PolarHBondContact O-N 2.81Å
10A69.3Low70Confident22 Ų22109.9 Ų109.918%0.18261%0.609CS.*SBendtrans-64.6138.1173.300000109.1H6 P7 Q12H6-A10 PolarHBondContact O-N 3.3Å; P7-A10 PolarHBondContact O-N 3.19Å; A10-Q12 PolarHBondContact O-N 3.42Å
11S63.4Low70Confident130 Ų130108.6 Ų108.691%0.90961%0.606SS**  trans-64.912.7179.254.80000114.6Q13S11-Q13 PolarHBondContact O-N 3.11Å; S11-Q13 VanDerWaalsContact O-N 3.16Å
12Q72.9Confident71Confident140 Ų140109.5 Ų109.565%0.65458%0.583SS**  trans-59.9121.4171.5-77177.96.300108.4A10 R14A10-Q12 PolarHBondContact O-N 3.42Å; Q12-R14 WeakPolarHBondContact O-CG 3.17Å; Q12-R14 PolarHBondContact O-N 3.29Å
13Q69.3Low71.2Confident199 Ų199105.6 Ų105.693%0.9355%0.552SS**  trans-5797.4174.8-175.2179.7-54.600108.8S11S11-Q13 PolarHBondContact O-N 3.11Å; S11-Q13 VanDerWaalsContact O-N 3.16Å
14R72.1Confident71.5Confident90 Ų90100.7 Ų100.734%0.3453%0.531SS..  trans-91.8139.1176.4-71.5171.9-179.8-129.9-11.4108.7P7 Q12 P16 F19P7-R14 VanDerWaalsContact O-CZ 3.31Å; P7-R14 PolarHBondContact O-NH2 3.41Å; Q12-R14 WeakPolarHBondContact O-CG 3.17Å; Q12-R14 PolarHBondContact O-N 3.29Å; R14-P16 WeakPolarHBondContact O-CD 3.36Å; R14-F19 HydrophobicContact CB-CB 4.33Å
15D78.2Confident71.5Confident107 Ų107100.8 Ų100.857%0.57252%0.521SS*.  trans-59.1122.2169.6-65-54.5000108.7S17 T18 F19D15-S17 PolarHBondContact O-N 3.34Å; D15-S17 VanDerWaalsContact O-N 3.12Å; D15-T18 WeakPolarHBondContact O-CB 3.13Å; D15-T18 PolarHBondContact O-N 3.12Å; D15-F19 PolarHBondContact O-N 3.43Å
16P69.1Low71.2Confident81 Ų81105.4 Ų105.453%0.52653%0.528SS..Hα-helixtrans-63.1-23-17420.4-29.9000112.3R14 Y20R14-P16 WeakPolarHBondContact O-CD 3.36Å; P16-Y20 WeakPolarHBondContact O-CB 3.14Å; P16-Y20 WeakPolarHBondContact O-CD2 3.22Å; P16-Y20 PolarHBondContact O-N 3.26Å
17S68.4Low70.9Confident63 Ų63107.9 Ų107.944%0.44153%0.534SS..Hα-helixtrans-68.4-38.5170.149.20000112.6D15 I24D15-S17 PolarHBondContact O-N 3.34Å; D15-S17 VanDerWaalsContact O-N 3.12Å; S17-I24 WeakPolarHBondContact O-CD1 3.39Å; S17-I24 WeakPolarHBondContact O-CG1 3.49Å
18T70.4Confident70.8Confident109 Ų109111.1 Ų111.167%0.66954%0.536SS*.Hα-helixtrans-75.4-33.9-176.9-56.60000112.4D15D15-T18 WeakPolarHBondContact O-CB 3.13Å; D15-T18 PolarHBondContact O-N 3.12Å
19F70.1Confident70.4Confident66 Ų66112.6 Ų112.629%0.28954%0.537SS..Hα-helixtrans-84.7-23-176.5-168-114000113.8L8 R14 D15 P21L8-F19 WeakPolarHBondContact O-CZ 3.22Å; L8-F19 HydrophobicContact CD2-CE2 3.79Å; L8-F19 HydrophobicContact CB-CZ 4.4Å; L8-F19 HydrophobicContact CB-CE2 4.33Å; R14-F19 HydrophobicContact CB-CB 4.33Å; D15-F19 PolarHBondContact O-N 3.43Å; F19-P21 WeakPolarHBondContact O-CD 3.36Å
20Y81.8Confident70.2Confident106 Ų106111.7 Ų111.742%0.41654%0.539SS..  trans-115.684.2-175.1-70.4-59.1000110.3P16 W22 L23P16-Y20 WeakPolarHBondContact O-CB 3.14Å; P16-Y20 WeakPolarHBondContact O-CD2 3.22Å; P16-Y20 PolarHBondContact O-N 3.26Å; Y20-W22 PolarHBondContact O-N 2.89Å; Y20-W22 VanDerWaalsContact O-N 3.12Å; Y20-W22 AromaticContact CD1-NE1 3.37Å; Y20-W22 AromaticContact CG-NE1 3.65Å; Y20-W22 HydrophobicContact CD1-CZ2 4.34Å; Y20-L23 WeakPolarHBondContact O-CB 3.49Å; Y20-L23 PolarHBondContact O-N 3.19Å
21P70.4Confident70.1Confident83 Ų83114.3 Ų114.354%0.53957%0.568SS.*Hα-helixtrans-55.6-37-175.919.7-31.7000112.5F19 L23 I24 H25F19-P21 WeakPolarHBondContact O-CD 3.36Å; P21-L23 PolarHBondContact O-N 2.88Å; P21-I24 PolarHBondContact O-N 3.44Å; P21-H25 PolarHBondContact O-CD2 2.92Å; P21-H25 PolarHBondContact O-N 3.26Å
22W73.8Confident70.3Confident190 Ų190115.6 Ų115.672%0.7256%0.559SS**Hα-helixtrans-60.5-23.5175.560.8-2.4000115.1Y20 R26Y20-W22 PolarHBondContact O-N 2.89Å; Y20-W22 VanDerWaalsContact O-N 3.12Å; Y20-W22 AromaticContact CD1-NE1 3.37Å; Y20-W22 AromaticContact CG-NE1 3.65Å; Y20-W22 HydrophobicContact CD1-CZ2 4.34Å; W22-R26 PolarHBondContact O-N 3.2Å
23L72.5Confident70Confident47 Ų47118.7 Ų118.725%0.24657%0.565CS.*Hα-helixtrans-79.2-38.4-178.1-167.867.5000109.6Y20 P21 H25 R26 Y27Y20-L23 WeakPolarHBondContact O-CB 3.49Å; Y20-L23 PolarHBondContact O-N 3.19Å; P21-L23 PolarHBondContact O-N 2.88Å; L23-H25 VanDerWaalsContact C-N 3.31Å; L23-H25 PolarHBondContact O-N 2.68Å; L23-R26 PolarHBondContact O-N 3.45Å; L23-Y27 HydrophobicContact CD1-CD2 4.4Å; L23-Y27 WeakPolarHBondContact O-CD2 3.4Å; L23-Y27 HydrophobicContact CG-CE2 3.75Å; L23-Y27 HydrophobicContact CG-CD2 4.29Å; L23-Y27 VanDerWaalsContact CD1-CE2 3.49Å; L23-Y27 HydrophobicContact CD1-CE2 3.49Å
24I72.9Confident69.7Low69 Ų69118.3 Ų118.335%0.35456%0.561SS.*Hα-helixtrans-60.2-43.8174-53.3175.3000110.2S17 P21 R26 R28S17-I24 WeakPolarHBondContact O-CD1 3.39Å; S17-I24 WeakPolarHBondContact O-CG1 3.49Å; P21-I24 PolarHBondContact O-N 3.44Å; I24-R26 VanDerWaalsContact C-N 3.3Å; I24-R26 PolarHBondContact O-N 3.12Å; I24-R28 WeakPolarHBondContact O-CB 3.35Å; I24-R28 PolarHBondContact O-N 3.46Å
25H70.3Confident69.6Low96 Ų96121.5 Ų121.544%0.44458%0.58SS.*Hα-helixtrans-69.5-26.5-178.6-69.9-76000113.1P21 L23 Y29P21-H25 PolarHBondContact O-CD2 2.92Å; P21-H25 PolarHBondContact O-N 3.26Å; L23-H25 VanDerWaalsContact C-N 3.31Å; L23-H25 PolarHBondContact O-N 2.68Å; H25-Y29 VanDerWaalsContact O-CD2 3.23Å; H25-Y29 WeakPolarHBondContact O-CD2 3.43Å
26R68.6Low68.8Low179 Ų179119.3 Ų119.368%0.67558%0.582SS**Hα-helixtrans-68.1-43.4178.5-175.2177.7-67.2-169.7-1.2112.7W22 L23 I24W22-R26 PolarHBondContact O-N 3.2Å; L23-R26 PolarHBondContact O-N 3.45Å; I24-R26 VanDerWaalsContact C-N 3.3Å; I24-R26 PolarHBondContact O-N 3.12Å
27Y65.3Low68.2Low155 Ų155123 Ų12361%0.60859%0.59SS**Hα-helixtrans-88.9-16-175-59.5-68.1000113.7L23 Y29L23-Y27 HydrophobicContact CD1-CD2 4.4Å; L23-Y27 WeakPolarHBondContact O-CD2 3.4Å; L23-Y27 HydrophobicContact CG-CE2 3.75Å; L23-Y27 HydrophobicContact CG-CD2 4.29Å; L23-Y27 VanDerWaalsContact CD1-CE2 3.49Å; L23-Y27 HydrophobicContact CD1-CE2 3.49Å; Y27-Y29 VanDerWaalsContact C-N 3.34Å; Y27-Y29 PolarHBondContact O-N 3.36Å
28R67.3Low67.3Low143 Ų143124.6 Ų124.654%0.5460%0.601SS.*Hα-helixtrans-70.6-26.1-175.6-165.1116.964.1105.3-0.3114.1I24I24-R28 WeakPolarHBondContact O-CB 3.35Å; I24-R28 PolarHBondContact O-N 3.46Å
29Y62.3Low66.4Low116 Ų116127.6 Ų127.646%0.45561%0.61SS.*SBendtrans-108.3-2-172-58.1-69.7000114.7H25 Y27 G31 H32H25-Y29 VanDerWaalsContact O-CD2 3.23Å; H25-Y29 WeakPolarHBondContact O-CD2 3.43Å; Y27-Y29 VanDerWaalsContact C-N 3.34Å; Y27-Y29 PolarHBondContact O-N 3.36Å; Y29-G31 VanDerWaalsContact C-N 3.27Å; Y29-G31 PolarHBondContact O-N 3.4Å; Y29-H32 PolarHBondContact O-N 2.82Å
30L66.4Low65.6Low154 Ų154131 Ų13181%0.80664%0.635SS**THydrogen-bonded Turntrans-68.5-23-175.7-16962.5000113.4
31G66.3Low63.9Low77 Ų77130.5 Ų130.579%0.79465%0.648SS**THydrogen-bonded Turntrans-100.9-2.7179.100000115.6Y29Y29-G31 VanDerWaalsContact C-N 3.27Å; Y29-G31 PolarHBondContact O-N 3.4Å
32H67.6Low62.9Low158 Ų158134.4 Ų134.473%0.73166%0.658SS**SBendtrans-102.1-5.3-162.3-138.9-61.5000115.4Y29Y29-H32 PolarHBondContact O-N 2.82Å
33R66.4Low61.5Low204 Ų204130.8 Ų130.877%0.7766%0.659SS**SBendtrans-121.711.9-168.6-60.5-168-173.6-172.92.7116.1
34F63.3Low60.5Low192 Ų192136.6 Ų136.684%0.84269%0.685SS**  trans-142.573.3174.6-151-101.5000112.9
35Q69.7Low59.5Low157 Ų157139.8 Ų139.873%0.73470%0.703SS**  trans-105.168.3154.1-70.6-174.12.600107.8K37Q35-K37 WeakPolarHBondContact O-CG 3.39Å; Q35-K37 PolarHBondContact O-N 2.85Å
36G61.3Low58.7Low61 Ų61143.7 Ų143.763%0.62972%0.721SS**  trans-69.363169.800000111.1S38G36-S38 VanDerWaalsContact C-N 3.29Å; G36-S38 PolarHBondContact O-N 3.29Å
37K57.4Low58Low158 Ų158141.9 Ų141.969%0.68772%0.724SS**  trans-78.289.9159.330.2167.1170.9-176.80106Q35 M39Q35-K37 WeakPolarHBondContact O-CG 3.39Å; Q35-K37 PolarHBondContact O-N 2.85Å; K37-M39 PolarHBondContact O-N 3.2Å; K37-M39 VanDerWaalsContact C-N 3.26Å
38S48.5Very low57.2Low96 Ų96143.9 Ų143.967%0.67174%0.739SS**  trans-53.198.5156.5-175.50000106.9G36 V40G36-S38 VanDerWaalsContact C-N 3.29Å; G36-S38 PolarHBondContact O-N 3.29Å; S38-V40 PolarHBondContact O-N 2.8Å
39M52.3Low56.4Low173 Ų173146.7 Ų146.785%0.85276%0.755SS**SBendtrans-56.8132.2156.6-77.2176.6154.400105.7K37K37-M39 PolarHBondContact O-N 3.2Å; K37-M39 VanDerWaalsContact C-N 3.26Å
40V53.1Low55.9Low137 Ų137145.3 Ų145.383%0.8377%0.768SS**SBendtrans92.166.6-169.5-162.30000113.9S38S38-V40 PolarHBondContact O-N 2.8Å
41S46.8Very low54.9Low96 Ų96148 Ų14867%0.67177%0.772SS**  -175.6116.7117.955.40000107.6P43S41-P43 WeakPolarHBondContact O-CD 3.49Å
42E48.3Very low53.9Low164 Ų164148.3 Ų148.377%0.76677%0.768SS**  trans-43.6142.5156-110.5178.4106.400109.8E44E42-E44 WeakPolarHBondContact OE1-CG 3.45Å
43P45.2Very low53.1Low114 Ų114152.7 Ų152.774%0.7478%0.778SS**  -130125.3119.532.9-23.1000109.8S41 N45S41-P43 WeakPolarHBondContact O-CD 3.49Å; P43-N45 PolarHBondContact O-N 3.16Å
44E51.4Low52.2Low170 Ų170146.1 Ų146.179%0.79477%0.774SS**  trans-45106.2151.6-59.7176.5132.700109.1E42E42-E44 WeakPolarHBondContact OE1-CG 3.45Å
45N52.5Low51.8Low136 Ų136148.9 Ų148.973%0.72778%0.779SS**  trans-147.986.3150.5-149.6-109.7000109.5P43P43-N45 PolarHBondContact O-N 3.16Å
46E53Low50.7Low177 Ų177151.9 Ų151.983%0.82778%0.783SS**  trans-24.2146.2139.3-163.7172.3-173.500112.7
47I53.9Low50.2Low141 Ų141155 Ų15572%0.72379%0.785SS**  trans97.270-178.2-42.4154.2000114.7
48Q49Very low49.7Very low198 Ų198157.7 Ų157.793%0.92579%0.791SS**  trans-162.941.3138.8-107.5165.880.200112.9A50Q48-A50 PolarHBondContact O-N 3.34Å
49K49.4Very low49.3Very low202 Ų202161 Ų16188%0.87879%0.794SS**  trans-60.5131.3157.8169.9-178.9157.2-170.90109
50A51.2Low48.8Very low87 Ų87157.7 Ų157.772%0.71979%0.787SS**  trans79.4139158.800000118.4Q48Q48-A50 PolarHBondContact O-N 3.34Å
51K46.9Very low48.1Very low209 Ų209157.3 Ų157.391%0.90979%0.786SS**  trans86.2108.1171.5-144.1172.6-173.5177.70111.6
52A44.5Very low48.6Very low84 Ų84161.6 Ų161.669%0.69480%0.795SS**  cis-162.7107.440.300000107.7
53R51.3Low48.8Very low250 Ų250161.7 Ų161.794%0.94380%0.795SS**  9109.794.1-87-171.7171.3-134.4-0113.3
54G48.2Very low49.2Very low67 Ų67164.5 Ų164.569%0.69180%0.796SS**  trans85.5103.6144.400000115.8R56G54-R56 PolarHBondContact O-N 3.47Å
55R53.4Low49.2Very low250 Ų250166.4 Ų166.494%0.94380%0.796SS**  1.6107.7126.7-66.9162.283.8-1787.7113.8
56R47.9Very low49.1Very low219 Ų219165.9 Ų165.983%0.82679%0.793SS**  -171.6109.4122.5-119.5174.9176.5179.3-2111.9G54G54-R56 PolarHBondContact O-N 3.47Å
57L50Low49.2Very low127 Ų127163.6 Ų163.667%0.66579%0.791SS**  trans-30129.3140.7-172.773.8000112.4F59L57-F59 HydrophobicContact CD1-CD2 4.17Å; L57-F59 HydrophobicContact CD1-CE2 3.65Å; L57-F59 HydrophobicContact CD1-CZ 4.39Å; L57-F59 HydrophobicContact CG-CD2 4.45Å; L57-F59 HydrophobicContact CG-CE2 4.27Å
58R47Very low49.2Very low214 Ų214162 Ų16281%0.80879%0.79SS**  -176.9113126.4-94.8163.3-154.9-1325.8111.4
59F40.7Very low48.9Very low167 Ų167164.9 Ų164.973%0.73280%0.803SS**  trans-14.5141.8150.1-66-79.9000120L57L57-F59 HydrophobicContact CD1-CD2 4.17Å; L57-F59 HydrophobicContact CD1-CE2 3.65Å; L57-F59 HydrophobicContact CD1-CZ 4.39Å; L57-F59 HydrophobicContact CG-CD2 4.45Å; L57-F59 HydrophobicContact CG-CE2 4.27Å
60S41.5Very low48.9Very low103 Ų103163 Ų16372%0.7280%0.799SS**  trans59.2147.2138.3-32.10000118.4
61T38.5Very low48.7Very low129 Ų129167 Ų16779%0.79180%0.803SS**  cis-162.715033.5-59.40000107.4
62E56.9Low48.9Very low185 Ų185164.7 Ų164.786%0.86480%0.797SS**  trans-47.5140.1164.9-78162.183.300113
63E51.3Low49.1Very low167 Ų167169.4 Ų169.478%0.7880%0.803SS**  trans-156.2111136.7-162.2172.5123.800110.4
64K55.3Low49Very low172 Ų172164.4 Ų164.475%0.74880%0.795SS**  trans-58.5149164.9-79.5-177.7170.3-175.30111.1
65R50.9Low49Very low211 Ų211170.9 Ų170.980%0.79680%0.802SS**  176.398.1123.8-90.3151.5-170170.84.5106.7
66D49.5Very low48.7Very low125 Ų125165.2 Ų165.267%0.66879%0.792SS**  748494.1-69.1-46.9000112.5
67T54.9Low48.8Very low128 Ų128161.1 Ų161.179%0.78579%0.789SS**  40.3169.3124.650000122.4
68P55.6Low48.7Very low108 Ų108163.9 Ų163.970%0.70180%0.799SS**  -119.4177.5-115.640.9-22.5000113.3
69H42Very low48.8Very low258 Ų258159.4 Ų159.4100%1.19480%0.798SS**  trans-161.20131.1-126.7-47.9000112.6

Retrieved 69 of 69 residues in 251.5 ms (Link to these results)