A0A087WQT6_MOUSE Loading...

Caspase-8

AlphaFold DB , UniProt , Accession A0A087WQT6, Species MOUSE (Mus musculus, Mouse), Gene Casp8, Length 500 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M50.9Low52.4Low192 Ų192113.6 Ų113.695%0.94659%0.59SS**  0-58.60-111.7171.974.600111.8V3 L4 L5M1-V3 PolarHBondContact O-N 3.3Å; M1-L4 WeakPolarHBondContact O-CB 3.43Å; M1-L4 PolarHBondContact O-N 3.1Å; M1-L5 PolarHBondContact O-N 3.34Å
2C51.5Low52.6Low93 Ų93112.3 Ų112.363%0.62858%0.583SS**Hα-helixtrans-52.8-49.1-179.1-58.20000114.5L4 L5 E6C2-L4 PolarHBondContact O-N 3.2Å; C2-L4 VanDerWaalsContact O-N 3.13Å; C2-L5 WeakPolarHBondContact O-CA 3.34Å; C2-L5 WeakPolarHBondContact O-CB 3.27Å; C2-L5 PolarHBondContact O-N 3.17Å; C2-E6 PolarHBondContact O-N 3.36Å
3V52.3Low52.4Low99 Ų99113.6 Ų113.660%0.659%0.585SS**Hα-helixtrans-58.9-29.5178.6-175.10000113.4M1 L7M1-V3 PolarHBondContact O-N 3.3Å; V3-L7 HydrophobicContact CG1-CD1 4.16Å; V3-L7 WeakPolarHBondContact O-CB 3.33Å; V3-L7 WeakPolarHBondContact O-CD1 3.39Å; V3-L7 VanDerWaalsContact O-CG 3.26Å; V3-L7 WeakPolarHBondContact O-CG 3.11Å; V3-L7 PolarHBondContact O-N 3.44Å
4L51.4Low52.1Low121 Ų121112.4 Ų112.463%0.63458%0.579SS**Hα-helixtrans-77.7-25.9176-103.1152.4000112.4M1 C2 L8M1-L4 WeakPolarHBondContact O-CB 3.43Å; M1-L4 PolarHBondContact O-N 3.1Å; C2-L4 PolarHBondContact O-N 3.2Å; C2-L4 VanDerWaalsContact O-N 3.13Å; L4-L8 WeakPolarHBondContact O-CB 3.37Å; L4-L8 WeakPolarHBondContact O-CD1 3.3Å; L4-L8 WeakPolarHBondContact O-CG 3.45Å; L4-L8 PolarHBondContact O-N 2.84Å; L4-L8 VanDerWaalsContact O-N 3.13Å
5L51.5Low52.1Low106 Ų106113 Ų11356%0.55558%0.576SS**Hα-helixtrans-80.8-37174.4-75162.5000111.6M1 C2 L8 S9M1-L5 PolarHBondContact O-N 3.34Å; C2-L5 WeakPolarHBondContact O-CA 3.34Å; C2-L5 WeakPolarHBondContact O-CB 3.27Å; C2-L5 PolarHBondContact O-N 3.17Å; L5-L8 PolarHBondContact O-N 3.48Å; L5-S9 PolarHBondContact O-N 2.93Å; L5-S9 PolarHBondContact O-OG 2.88Å
6E50.9Low51.9Low119 Ų119117.1 Ų117.156%0.55658%0.584SS**Hα-helixtrans-66.9-43.1172.6-70.7169.415800111.2C2 L8 S9 D10C2-E6 PolarHBondContact O-N 3.36Å; E6-L8 VanDerWaalsContact C-N 3.29Å; E6-L8 PolarHBondContact O-N 2.69Å; E6-S9 WeakPolarHBondContact CA-OG 3.44Å; E6-S9 PolarHBondContact O-N 3.1Å; E6-S9 PolarHBondContact O-OG 3.31Å; E6-D10 WeakPolarHBondContact O-CB 3.34Å; E6-D10 PolarHBondContact O-N 2.87Å
7L51.6Low51.2Low92 Ų92117.2 Ų117.248%0.48259%0.586SS.*Hα-helixtrans-65-31.8171.9-73.4169.2000112.6V3 W11V3-L7 HydrophobicContact CG1-CD1 4.16Å; V3-L7 WeakPolarHBondContact O-CB 3.33Å; V3-L7 WeakPolarHBondContact O-CD1 3.39Å; V3-L7 VanDerWaalsContact O-CG 3.26Å; V3-L7 WeakPolarHBondContact O-CG 3.11Å; V3-L7 PolarHBondContact O-N 3.44Å; L7-W11 VanDerWaalsContact O-CB 3.27Å; L7-W11 WeakPolarHBondContact O-CB 3.3Å; L7-W11 PolarHBondContact O-N 2.68Å
8L53.2Low50.7Low98 Ų98118.4 Ų118.451%0.51359%0.594SS.*Hα-helixtrans-73.3-34.8172.9-90.9163.1000112.6L4 L5 E6 L12L4-L8 WeakPolarHBondContact O-CB 3.37Å; L4-L8 WeakPolarHBondContact O-CD1 3.3Å; L4-L8 WeakPolarHBondContact O-CG 3.45Å; L4-L8 PolarHBondContact O-N 2.84Å; L4-L8 VanDerWaalsContact O-N 3.13Å; L5-L8 PolarHBondContact O-N 3.48Å; E6-L8 VanDerWaalsContact C-N 3.29Å; E6-L8 PolarHBondContact O-N 2.69Å; L8-L12 VanDerWaalsContact O-CB 3.28Å; L8-L12 WeakPolarHBondContact O-CB 3.26Å; L8-L12 PolarHBondContact O-N 3.37Å
9S54.3Low50.6Low56 Ų56118.2 Ų118.239%0.39259%0.593SS.*Hα-helixtrans-70.1-42.1172.661.20000111.2L5 E6 W11 L12 Q13L5-S9 PolarHBondContact O-N 2.93Å; L5-S9 PolarHBondContact O-OG 2.88Å; E6-S9 WeakPolarHBondContact CA-OG 3.44Å; E6-S9 PolarHBondContact O-N 3.1Å; E6-S9 PolarHBondContact O-OG 3.31Å; S9-W11 PolarHBondContact O-N 3.43Å; S9-L12 CarbonylContact O-C 3.01Å; S9-L12 PolarHBondContact O-N 3.29Å; S9-Q13 VanDerWaalsContact O-CB 3.28Å; S9-Q13 WeakPolarHBondContact O-CB 3.38Å; S9-Q13 PolarHBondContact O-N 3.49Å
10D53.3Low50.5Low92 Ų92122.4 Ų122.449%0.49260%0.602SS.*Hα-helixtrans-66.8-36.3176.1-75-13.6000111.6E6 Q13 L14E6-D10 WeakPolarHBondContact O-CB 3.34Å; E6-D10 PolarHBondContact O-N 2.87Å; D10-Q13 PolarHBondContact O-N 3.12Å; D10-L14 WeakPolarHBondContact O-CB 3.35Å; D10-L14 WeakPolarHBondContact O-CD1 3.47Å; D10-L14 VanDerWaalsContact O-CG 3.23Å; D10-L14 WeakPolarHBondContact O-CG 3.46Å; D10-L14 PolarHBondContact O-N 3.43Å
11W56Low50.8Low182 Ų182120.8 Ų120.869%0.68959%0.594SS**Hα-helixtrans-70.6-35.5170.8-89.574.3000112.9L7 S9 F15L7-W11 VanDerWaalsContact O-CB 3.27Å; L7-W11 WeakPolarHBondContact O-CB 3.3Å; L7-W11 PolarHBondContact O-N 2.68Å; S9-W11 PolarHBondContact O-N 3.43Å; W11-F15 WeakPolarHBondContact O-CB 3.3Å; W11-F15 PolarHBondContact O-N 3.26Å
12L55Low51.7Low97 Ų97116.1 Ų116.151%0.50857%0.573SS.*Hα-helixtrans-68.2-38.3171.7-90.3158.7000111.6L8 S9 F15 Y16L8-L12 VanDerWaalsContact O-CB 3.28Å; L8-L12 WeakPolarHBondContact O-CB 3.26Å; L8-L12 PolarHBondContact O-N 3.37Å; S9-L12 CarbonylContact O-C 3.01Å; S9-L12 PolarHBondContact O-N 3.29Å; L12-F15 PolarHBondContact O-N 2.98Å; L12-Y16 WeakPolarHBondContact O-CB 3.43Å; L12-Y16 WeakPolarHBondContact O-CD2 3.41Å; L12-Y16 PolarHBondContact O-N 3.17Å
13Q49.8Very low52.9Low130 Ų130112.8 Ų112.861%0.60755%0.548SS*.Hα-helixtrans-66.2-44.6174.7-151.296.6-0.500110S9 D10 F15 Y16 L17S9-Q13 VanDerWaalsContact O-CB 3.28Å; S9-Q13 WeakPolarHBondContact O-CB 3.38Å; S9-Q13 PolarHBondContact O-N 3.49Å; D10-Q13 PolarHBondContact O-N 3.12Å; Q13-F15 VanDerWaalsContact C-N 3.35Å; Q13-Y16 CarbonylContact O-C 3.6Å; Q13-Y16 PolarHBondContact O-N 3.41Å; Q13-L17 HydrophobicContact CG-CD1 4.21Å; Q13-L17 WeakPolarHBondContact O-CB 3.32Å; Q13-L17 WeakPolarHBondContact O-CD1 3.12Å; Q13-L17 PolarHBondContact O-N 3.18Å
14L48Very low54.2Low97 Ų97113.2 Ų113.251%0.50854%0.543SS..Hα-helixtrans-67.8-30.9174.8-77.5165.4000112.7D10 L17 L18D10-L14 WeakPolarHBondContact O-CB 3.35Å; D10-L14 WeakPolarHBondContact O-CD1 3.47Å; D10-L14 VanDerWaalsContact O-CG 3.23Å; D10-L14 WeakPolarHBondContact O-CG 3.46Å; D10-L14 PolarHBondContact O-N 3.43Å; L14-L17 PolarHBondContact O-N 2.85Å; L14-L18 VanDerWaalsContact O-CB 3.31Å; L14-L18 WeakPolarHBondContact O-CB 3.38Å; L14-L18 PolarHBondContact O-N 3.35Å
15F52.3Low55.5Low121 Ų121110 Ų11053%0.53153%0.531SS..Hα-helixtrans-74.9-38.6173.7-166.8-103.4000111.2W11 L12 Q13 L17 L18 I19W11-F15 WeakPolarHBondContact O-CB 3.3Å; W11-F15 PolarHBondContact O-N 3.26Å; L12-F15 PolarHBondContact O-N 2.98Å; Q13-F15 VanDerWaalsContact C-N 3.35Å; F15-L17 VanDerWaalsContact C-N 3.32Å; F15-L18 PolarHBondContact O-N 3.27Å; F15-I19 HydrophobicContact CD1-CD1 3.9Å; F15-I19 HydrophobicContact CD2-CD1 4.49Å; F15-I19 HydrophobicContact CE1-CD1 3.46Å; F15-I19 VanDerWaalsContact CE1-CD1 3.46Å; F15-I19 HydrophobicContact CE2-CD1 4.12Å; F15-I19 HydrophobicContact CG-CD1 4.4Å; F15-I19 HydrophobicContact CZ-CD1 3.59Å; F15-I19 WeakPolarHBondContact O-CG1 3.47Å; F15-I19 PolarHBondContact O-N 2.98Å
16Y48.1Very low57Low179 Ų179105.6 Ų105.670%0.70251%0.509SS*.Hα-helixtrans-66.6-29.2168.5-99.4-88.1000113L12 Q13 R20L12-Y16 WeakPolarHBondContact O-CB 3.43Å; L12-Y16 WeakPolarHBondContact O-CD2 3.41Å; L12-Y16 PolarHBondContact O-N 3.17Å; Q13-Y16 CarbonylContact O-C 3.6Å; Q13-Y16 PolarHBondContact O-N 3.41Å; Y16-R20 PolarHBondContact O-N 2.85Å
17L40.3Very low58.6Low119 Ų119100.4 Ų100.462%0.62349%0.485SS*.Hα-helixtrans-79-31.4169.6-93.390.9000112.5Q13 L14 F15Q13-L17 HydrophobicContact CG-CD1 4.21Å; Q13-L17 WeakPolarHBondContact O-CB 3.32Å; Q13-L17 WeakPolarHBondContact O-CD1 3.12Å; Q13-L17 PolarHBondContact O-N 3.18Å; L14-L17 PolarHBondContact O-N 2.85Å; F15-L17 VanDerWaalsContact C-N 3.32Å
18L42Very low60.2Low139 Ų139101.7 Ų101.773%0.72848%0.484SS*.Hα-helixtrans-72.7-28.4174.9-116.271.5000112.7L14 F15L14-L18 VanDerWaalsContact O-CB 3.31Å; L14-L18 WeakPolarHBondContact O-CB 3.38Å; L14-L18 PolarHBondContact O-N 3.35Å; F15-L18 PolarHBondContact O-N 3.27Å
19I49.7Very low61.7Low113 Ų11398 Ų9858%0.57947%0.468SS*.THydrogen-bonded Turntrans-106.336.2175.8-44.2174.3000110.2F15F15-I19 HydrophobicContact CD1-CD1 3.9Å; F15-I19 HydrophobicContact CD2-CD1 4.49Å; F15-I19 HydrophobicContact CE1-CD1 3.46Å; F15-I19 VanDerWaalsContact CE1-CD1 3.46Å; F15-I19 HydrophobicContact CE2-CD1 4.12Å; F15-I19 HydrophobicContact CG-CD1 4.4Å; F15-I19 HydrophobicContact CZ-CD1 3.59Å; F15-I19 WeakPolarHBondContact O-CG1 3.47Å; F15-I19 PolarHBondContact O-N 2.98Å
20R48.8Very low63.2Low203 Ų20395.3 Ų95.377%0.76645%0.449SS*.  trans-99.6100.1140.2-77.6-162.7179.1-137.6-0.4107.4Y16 D22Y16-R20 PolarHBondContact O-N 2.85Å; R20-D22 PolarHBondContact O-N 3.28Å; R20-D22 VanDerWaalsContact O-N 3.16Å
21M56.7Low64.9Low88 Ų8891.3 Ų91.343%0.43343%0.429SS..  trans-55.4122.4157.1-66.1175.675.900106.5F23 S25 C26 A29 F98M21-F23 PolarHBondContact O-N 3.11Å; M21-S25 WeakPolarHBondContact CE-O 3.46Å; M21-C26 HydrophobicContact CB-CB 4.07Å; M21-A29 HydrophobicContact CE-CB 3.59Å; M21-F98 HydrophobicContact CE-CD1 4.21Å; M21-F98 HydrophobicContact CE-CE1 4.2Å; M21-F98 HydrophobicContact SD-CD1 3.93Å; M21-F98 HydrophobicContact SD-CE1 4.27Å
22D69.1Low66.4Low94 Ų9487.8 Ų87.850%0.50342%0.42SS..  trans-45.8138.9167158.340.7000108.7R20 Q24 S25 C26R20-D22 PolarHBondContact O-N 3.28Å; R20-D22 VanDerWaalsContact O-N 3.16Å; D22-Q24 PolarHBondContact O-N 2.73Å; D22-Q24 VanDerWaalsContact O-N 3.09Å; D22-Q24 PolarHBondContact OD1-N 2.7Å; D22-Q24 VanDerWaalsContact OD2-CB 3.31Å; D22-Q24 WeakPolarHBondContact OD2-CB 3.35Å; D22-S25 CarbonylContact O-C 3.31Å; D22-S25 VanDerWaalsContact O-CA 3.31Å; D22-S25 WeakPolarHBondContact O-CA 3.24Å; D22-S25 VanDerWaalsContact O-CB 3.29Å; D22-S25 WeakPolarHBondContact O-CB 3.42Å; D22-S25 PolarHBondContact O-N 3.27Å; D22-S25 PolarHBondContact OD2-OG 3.38Å; D22-C26 PolarHBondContact O-N 2.94Å
23F77.1Confident68Low23 Ų2388.4 Ų88.410%0.10142%0.42CS..Hα-helixtrans-52.2-37.7-175166.9-104.8000112M21 L27 R69 E75 E76 L79M21-F23 PolarHBondContact O-N 3.11Å; F23-L27 HydrophobicContact CD1-CD1 4.28Å; F23-L27 HydrophobicContact CD2-CD1 4.44Å; F23-L27 HydrophobicContact CE1-CD1 3.83Å; F23-L27 HydrophobicContact CE2-CD1 4.01Å; F23-L27 HydrophobicContact CE2-CG 4.44Å; F23-L27 HydrophobicContact CZ-CD1 3.68Å; F23-L27 WeakPolarHBondContact O-CG 3.43Å; F23-L27 PolarHBondContact O-N 3.5Å; F23-L27 VanDerWaalsContact O-N 3.09Å; F23-R69 HydrophobicContact CE1-CG 4.47Å; F23-R69 HydrophobicContact CZ-CG 4.43Å; F23-E75 VanDerWaalsContact CE2-C 3.43Å; F23-E75 WeakPolarHBondContact CE2-O 3.33Å; F23-E76 HydrophobicContact CB-CB 4.24Å; F23-E76 HydrophobicContact CB-CG 4.01Å; F23-E76 HydrophobicContact CD1-CB 4.37Å; F23-E76 HydrophobicContact CD2-CB 4.2Å; F23-E76 HydrophobicContact CG-CB 4.05Å; F23-E76 HydrophobicContact CG-CG 4.35Å; F23-L79 HydrophobicContact CD2-CD2 4.29Å; F23-L79 HydrophobicContact CE2-CD2 3.71Å
24Q78.8Confident69.9Low108 Ų10883 Ų8351%0.50540%0.395SS..Hα-helixtrans-63.9-41.1173.2-163.398.97.100112.5D22 Y28D22-Q24 PolarHBondContact O-N 2.73Å; D22-Q24 VanDerWaalsContact O-N 3.09Å; D22-Q24 PolarHBondContact OD1-N 2.7Å; D22-Q24 VanDerWaalsContact OD2-CB 3.31Å; D22-Q24 WeakPolarHBondContact OD2-CB 3.35Å; Q24-Y28 WeakPolarHBondContact O-CB 3.41Å; Q24-Y28 PolarHBondContact O-N 3.44Å
25S79.7Confident71.7Confident55 Ų5580.1 Ų80.139%0.38539%0.389SS..Hα-helixtrans-71.3-35.9178.9-57.70000112.7M21 D22 Y28 A29M21-S25 WeakPolarHBondContact CE-O 3.46Å; D22-S25 CarbonylContact O-C 3.31Å; D22-S25 VanDerWaalsContact O-CA 3.31Å; D22-S25 WeakPolarHBondContact O-CA 3.24Å; D22-S25 VanDerWaalsContact O-CB 3.29Å; D22-S25 WeakPolarHBondContact O-CB 3.42Å; D22-S25 PolarHBondContact O-N 3.27Å; D22-S25 PolarHBondContact OD2-OG 3.38Å; S25-Y28 PolarHBondContact O-N 2.87Å; S25-A29 PolarHBondContact O-N 3.32Å
26C82.8Confident73.3Confident13 Ų1379.2 Ų79.29%0.08840%0.398CS..Hα-helixtrans-62.8-51.7172.5179.60000110.8M21 D22 Y28 A29 I30M21-C26 HydrophobicContact CB-CB 4.07Å; D22-C26 PolarHBondContact O-N 2.94Å; C26-Y28 VanDerWaalsContact C-N 3.28Å; C26-Y28 PolarHBondContact O-N 2.68Å; C26-A29 PolarHBondContact O-N 3.49Å; C26-I30 WeakPolarHBondContact O-CG1 3.13Å; C26-I30 PolarHBondContact O-N 3.38Å
27L84.8Confident75Confident10 Ų1078.7 Ų78.75%0.05240%0.402CS..Hα-helixtrans-60.6-36.2175.9-70.6176.6000112.6F23 A31 F65 L74 L82F23-L27 HydrophobicContact CD1-CD1 4.28Å; F23-L27 HydrophobicContact CD2-CD1 4.44Å; F23-L27 HydrophobicContact CE1-CD1 3.83Å; F23-L27 HydrophobicContact CE2-CD1 4.01Å; F23-L27 HydrophobicContact CE2-CG 4.44Å; F23-L27 HydrophobicContact CZ-CD1 3.68Å; F23-L27 WeakPolarHBondContact O-CG 3.43Å; F23-L27 PolarHBondContact O-N 3.5Å; F23-L27 VanDerWaalsContact O-N 3.09Å; L27-A31 VanDerWaalsContact O-CB 3.24Å; L27-A31 WeakPolarHBondContact O-CB 3.22Å; L27-A31 PolarHBondContact O-N 2.85Å; L27-F65 HydrophobicContact CB-CD2 4.15Å; L27-F65 HydrophobicContact CD2-CB 4.46Å; L27-F65 HydrophobicContact CD2-CD2 4.02Å; L27-F65 HydrophobicContact CD2-CE2 4.48Å; L27-F65 HydrophobicContact CD2-CG 4.25Å; L27-L74 HydrophobicContact CD2-CD1 4.44Å; L27-L82 HydrophobicContact CD2-CD2 3.62Å
28Y85.1Confident77.2Confident118 Ų11874.5 Ų74.546%0.46338%0.38SS..Hα-helixtrans-63.4-50.4174.8179.2-98.8000111.7Q24 S25 C26 I30 A31 E32 Q62Q24-Y28 WeakPolarHBondContact O-CB 3.41Å; Q24-Y28 PolarHBondContact O-N 3.44Å; S25-Y28 PolarHBondContact O-N 2.87Å; C26-Y28 VanDerWaalsContact C-N 3.28Å; C26-Y28 PolarHBondContact O-N 2.68Å; Y28-I30 PolarHBondContact O-N 3.2Å; Y28-A31 WeakPolarHBondContact O-CB 3.45Å; Y28-A31 PolarHBondContact O-N 3.21Å; Y28-E32 HydrophobicContact CD1-CG 4.22Å; Y28-E32 HydrophobicContact CE1-CG 3.71Å; Y28-E32 HydrophobicContact CE2-CG 4.12Å; Y28-E32 WeakPolarHBondContact CE2-OE1 3.43Å; Y28-E32 WeakPolarHBondContact O-CG 3.49Å; Y28-E32 PolarHBondContact O-N 2.81Å; Y28-E32 VanDerWaalsContact OH-CD 3.23Å; Y28-E32 PolarHBondContact OH-OE1 3.47Å; Y28-E32 PolarHBondContact OH-OE2 3.18Å; Y28-Q62 HydrophobicContact CD2-CG 4.43Å
29A83.7Confident79.5Confident20 Ų2068.5 Ų68.517%0.16535%0.349CS..Hα-helixtrans-63.3-40179.500000112.9M21 S25 C26 A31 E32 E33 F98M21-A29 HydrophobicContact CE-CB 3.59Å; S25-A29 PolarHBondContact O-N 3.32Å; C26-A29 PolarHBondContact O-N 3.49Å; A29-A31 VanDerWaalsContact C-N 3.28Å; A29-A31 PolarHBondContact O-N 3.42Å; A29-E32 PolarHBondContact O-N 3.23Å; A29-E33 WeakPolarHBondContact O-CG 3.5Å; A29-E33 PolarHBondContact O-N 3.44Å; A29-F98 HydrophobicContact CB-CD1 4.14Å; A29-F98 HydrophobicContact CB-CE1 3.56Å; A29-F98 HydrophobicContact CB-CZ 3.93Å
30I86.4Confident81.2Confident0 Ų065.2 Ų65.20%034%0.338CS..Hα-helixtrans-61-39.9172.5-67170.7000110.4C26 Y28 E33 L34 F65 L82 L86 L94 F98 L99C26-I30 WeakPolarHBondContact O-CG1 3.13Å; C26-I30 PolarHBondContact O-N 3.38Å; Y28-I30 PolarHBondContact O-N 3.2Å; I30-E33 PolarHBondContact O-N 3.11Å; I30-L34 HydrophobicContact CG2-CD1 4Å; I30-L34 WeakPolarHBondContact O-CD1 3.25Å; I30-L34 VanDerWaalsContact O-CG 3.25Å; I30-L34 WeakPolarHBondContact O-CG 3.4Å; I30-F65 HydrophobicContact CB-CE2 4.23Å; I30-F65 HydrophobicContact CG2-CE2 3.82Å; I30-F65 HydrophobicContact CG2-CZ 3.8Å; I30-L82 HydrophobicContact CD1-CD2 3.92Å; I30-L86 HydrophobicContact CG2-CD1 4.14Å; I30-L86 HydrophobicContact CG2-CD2 4.38Å; I30-L94 HydrophobicContact CG2-CD1 4.21Å; I30-F98 HydrophobicContact CD1-CB 3.82Å; I30-F98 HydrophobicContact CD1-CG 4.5Å; I30-F98 HydrophobicContact CG1-CB 3.68Å; I30-F98 HydrophobicContact CG1-CD2 3.86Å; I30-F98 HydrophobicContact CG1-CG 3.82Å; I30-L99 HydrophobicContact CD1-CD1 4.19Å; I30-L99 HydrophobicContact CD1-CD2 3.89Å; I30-L99 HydrophobicContact CD1-CG 3.97Å
31A88.1Confident83.2Confident8 Ų855.9 Ų55.97%0.06631%0.305CS..Hα-helixtrans-71-33.5-179.100000114.3L27 Y28 A29 E33 L34 A61 Q62 F65L27-A31 VanDerWaalsContact O-CB 3.24Å; L27-A31 WeakPolarHBondContact O-CB 3.22Å; L27-A31 PolarHBondContact O-N 2.85Å; Y28-A31 WeakPolarHBondContact O-CB 3.45Å; Y28-A31 PolarHBondContact O-N 3.21Å; A29-A31 VanDerWaalsContact C-N 3.28Å; A29-A31 PolarHBondContact O-N 3.42Å; A31-E33 VanDerWaalsContact C-N 3.3Å; A31-L34 PolarHBondContact O-N 3.13Å; A31-A61 HydrophobicContact CB-CB 3.81Å; A31-Q62 HydrophobicContact CB-CB 4.37Å; A31-Q62 HydrophobicContact CB-CG 3.47Å; A31-Q62 VanDerWaalsContact CB-CG 3.47Å; A31-F65 HydrophobicContact CB-CD2 4.06Å; A31-F65 HydrophobicContact CB-CE2 3.83Å
32E88.8Confident84.7Confident109 Ų10951.7 Ų51.751%0.50928%0.284SS..Hα-helixtrans-68.3-29.8175.8-66.4-67.411300112.3Y28 A29 Q62Y28-E32 HydrophobicContact CD1-CG 4.22Å; Y28-E32 HydrophobicContact CE1-CG 3.71Å; Y28-E32 HydrophobicContact CE2-CG 4.12Å; Y28-E32 WeakPolarHBondContact CE2-OE1 3.43Å; Y28-E32 WeakPolarHBondContact O-CG 3.49Å; Y28-E32 PolarHBondContact O-N 2.81Å; Y28-E32 VanDerWaalsContact OH-CD 3.23Å; Y28-E32 PolarHBondContact OH-OE1 3.47Å; Y28-E32 PolarHBondContact OH-OE2 3.18Å; A29-E32 PolarHBondContact O-N 3.23Å; E32-Q62 PolarHBondContact OE1-NE2 3.45Å
33E88.3Confident85.7Confident109 Ų10949.5 Ų49.551%0.50927%0.27SS..THydrogen-bonded Turntrans-84.9-5.1179.3-65.3-68.6157.800113.6A29 I30 A31 R91 L94 F98A29-E33 WeakPolarHBondContact O-CG 3.5Å; A29-E33 PolarHBondContact O-N 3.44Å; I30-E33 PolarHBondContact O-N 3.11Å; A31-E33 VanDerWaalsContact C-N 3.3Å; E33-R91 PolarHBondContact O-NH1 3.22Å; E33-R91 PolarHBondContact O-NH2 3.39Å; E33-L94 HydrophobicContact CB-CD1 4.28Å; E33-L94 HydrophobicContact CB-CD2 3.57Å; E33-L94 HydrophobicContact CG-CD2 4.01Å; E33-F98 HydrophobicContact CG-CE2 4.37Å
34L89.6Confident86.3Confident17 Ų1748.7 Ų48.79%0.08927%0.267CS..  trans-94.9119.8-178.9-73.3165.3000111.5I30 A31 D38 L42 A61 F65 L86 I89 R91 L94I30-L34 HydrophobicContact CG2-CD1 4Å; I30-L34 WeakPolarHBondContact O-CD1 3.25Å; I30-L34 VanDerWaalsContact O-CG 3.25Å; I30-L34 WeakPolarHBondContact O-CG 3.4Å; A31-L34 PolarHBondContact O-N 3.13Å; L34-D38 HydrophobicContact CB-CB 4.19Å; L34-D38 HydrophobicContact CD2-CB 3.6Å; L34-L42 HydrophobicContact CD1-CD1 3.72Å; L34-L42 HydrophobicContact CD2-CD1 4.07Å; L34-L42 HydrophobicContact CG-CD1 4.48Å; L34-A61 HydrophobicContact CB-CB 4.11Å; L34-A61 HydrophobicContact CD1-CB 3.98Å; L34-F65 HydrophobicContact CD1-CE2 4.23Å; L34-F65 HydrophobicContact CD1-CZ 3.6Å; L34-L86 HydrophobicContact CD2-CD2 4.1Å; L34-I89 HydrophobicContact CD2-CD1 3.7Å; L34-R91 HydrophobicContact CD2-CG 4.32Å; L34-L94 HydrophobicContact CD2-CD1 3.77Å; L34-L94 HydrophobicContact CG-CD1 3.91Å
35G86.7Confident86.7Confident37 Ų3743.6 Ų43.638%0.38124%0.243SC..  trans-76.1179.5179.600000114.2E37 D38 L39G35-E37 VanDerWaalsContact C-N 3.31Å; G35-E37 PolarHBondContact O-N 3.46Å; G35-D38 PolarHBondContact N-OD2 3.31Å; G35-D38 PolarHBondContact O-N 2.84Å; G35-L39 WeakPolarHBondContact O-CB 3.44Å; G35-L39 PolarHBondContact O-N 3.22Å
36S84.8Confident87.2Confident102 Ų10241 Ų4171%0.71323%0.225SC*.Hα-helixtrans-64.3-34.5175.6490000113.1A40S36-A40 PolarHBondContact O-N 2.8Å
37E83.2Confident87.4Confident167 Ų16741.2 Ų41.278%0.7823%0.225SC*.Hα-helixtrans-70.3-47.7176.3-65.6176.217400110.7G35 L39 A40 A41G35-E37 VanDerWaalsContact C-N 3.31Å; G35-E37 PolarHBondContact O-N 3.46Å; E37-L39 VanDerWaalsContact C-N 3.29Å; E37-L39 PolarHBondContact O-N 2.69Å; E37-A40 WeakPolarHBondContact O-CB 3.48Å; E37-A40 PolarHBondContact O-N 3.26Å; E37-A40 VanDerWaalsContact O-N 3.11Å; E37-A41 PolarHBondContact O-N 2.77Å
38D88.2Confident87.4Confident31 Ų3144.3 Ų44.317%0.16624%0.242CC..Hα-helixtrans-55.5-44.5172.4-62.4-56.8000111.3L34 G35 A40 A41 L42 I89 R91L34-D38 HydrophobicContact CB-CB 4.19Å; L34-D38 HydrophobicContact CD2-CB 3.6Å; G35-D38 PolarHBondContact N-OD2 3.31Å; G35-D38 PolarHBondContact O-N 2.84Å; D38-A40 VanDerWaalsContact C-N 3.33Å; D38-A40 PolarHBondContact O-N 3.36Å; D38-A41 PolarHBondContact O-N 3.42Å; D38-L42 WeakPolarHBondContact O-CB 3.34Å; D38-L42 VanDerWaalsContact O-CG 3.23Å; D38-L42 WeakPolarHBondContact O-CG 3.08Å; D38-L42 PolarHBondContact O-N 2.89Å; D38-I89 HydrophobicContact CB-CD1 4.07Å; D38-R91 IonicContact OD1-NH1 3.23Å; D38-R91 IonicContact OD2-NH1 2.74Å; D38-R91 PolarHBondContact OD2-NH1 2.8Å
39L88.6Confident87.3Confident13 Ų1342.2 Ų42.27%0.06823%0.234CC..Hα-helixtrans-63.2-37.4178.5-179.861.2000112.3G35 E37 K43 E59 A61 L64G35-L39 WeakPolarHBondContact O-CB 3.44Å; G35-L39 PolarHBondContact O-N 3.22Å; E37-L39 VanDerWaalsContact C-N 3.29Å; E37-L39 PolarHBondContact O-N 2.69Å; L39-K43 HydrophobicContact CD1-CG 4.45Å; L39-K43 HydrophobicContact CG-CD 4.25Å; L39-K43 VanDerWaalsContact O-CB 3.27Å; L39-K43 WeakPolarHBondContact O-CB 3.21Å; L39-K43 WeakPolarHBondContact O-CD 3.2Å; L39-K43 WeakPolarHBondContact O-CG 3.27Å; L39-K43 PolarHBondContact O-N 3.32Å; L39-E59 WeakPolarHBondContact CD2-O 3.18Å; L39-A61 HydrophobicContact CD1-CB 4.33Å; L39-L64 HydrophobicContact CD1-CB 4.31Å; L39-L64 HydrophobicContact CD1-CD2 4.07Å
40A87.1Confident87.3Confident44 Ų4441.6 Ų41.636%0.36423%0.227SC..Hα-helixtrans-66.9-43.1175.200000111.5S36 E37 D38 K43 F44S36-A40 PolarHBondContact O-N 2.8Å; E37-A40 WeakPolarHBondContact O-CB 3.48Å; E37-A40 PolarHBondContact O-N 3.26Å; E37-A40 VanDerWaalsContact O-N 3.11Å; D38-A40 VanDerWaalsContact C-N 3.33Å; D38-A40 PolarHBondContact O-N 3.36Å; A40-K43 WeakPolarHBondContact O-CB 3.28Å; A40-K43 PolarHBondContact O-N 3.01Å; A40-F44 PolarHBondContact O-N 3.32Å
41A89.2Confident87Confident8 Ų845.1 Ų45.17%0.06625%0.25CS..Hα-helixtrans-61.9-48.4174.700000112.2E37 D38 K43 F44 L45 I89 F126E37-A41 PolarHBondContact O-N 2.77Å; D38-A41 PolarHBondContact O-N 3.42Å; A41-K43 PolarHBondContact O-N 3.29Å; A41-F44 PolarHBondContact O-N 2.86Å; A41-L45 WeakPolarHBondContact O-CG 3.34Å; A41-L45 PolarHBondContact O-N 3.26Å; A41-I89 HydrophobicContact CB-CG2 3.61Å; A41-F126 HydrophobicContact CB-CD2 4.19Å; A41-F126 HydrophobicContact CB-CE2 3.4Å; A41-F126 VanDerWaalsContact CB-CE2 3.4Å; A41-F126 HydrophobicContact CB-CZ 3.95Å
42L89.8Confident86.4Confident0 Ų047.7 Ų47.70%026%0.261CS..Hα-helixtrans-61.7-42.2177.2-69.5173.9000112.1L34 D38 L45 C46 L64 L85 I89L34-L42 HydrophobicContact CD1-CD1 3.72Å; L34-L42 HydrophobicContact CD2-CD1 4.07Å; L34-L42 HydrophobicContact CG-CD1 4.48Å; D38-L42 WeakPolarHBondContact O-CB 3.34Å; D38-L42 VanDerWaalsContact O-CG 3.23Å; D38-L42 WeakPolarHBondContact O-CG 3.08Å; D38-L42 PolarHBondContact O-N 2.89Å; L42-L45 PolarHBondContact O-N 2.69Å; L42-C46 VanDerWaalsContact O-CB 3.29Å; L42-C46 WeakPolarHBondContact O-CB 3.44Å; L42-C46 PolarHBondContact O-N 3.42Å; L42-C46 PolarHBondContact O-SG 3.03Å; L42-L64 HydrophobicContact CB-CD2 3.61Å; L42-L64 HydrophobicContact CD1-CD2 4.47Å; L42-L85 HydrophobicContact CD2-CB 3.66Å; L42-L85 HydrophobicContact CD2-CD1 4.31Å; L42-L85 HydrophobicContact CD2-CD2 3.87Å; L42-L85 HydrophobicContact CD2-CG 4.16Å; L42-I89 HydrophobicContact CD1-CD1 4.23Å; L42-I89 HydrophobicContact CD2-CD1 3.98Å; L42-I89 HydrophobicContact CD2-CG1 4.44Å; L42-I89 HydrophobicContact CD2-CG2 4.12Å; L42-I89 HydrophobicContact CG-CD1 4.02Å; L42-I89 HydrophobicContact CG-CG2 4.37Å
43K88.6Confident85.7Confident47 Ų4749.2 Ų49.220%0.20427%0.266CS..Hα-helixtrans-56.4-50171.9-83.4169.8179.4173.30111.1L39 A40 A41 C46 L47 Q55 I58L39-K43 HydrophobicContact CD1-CG 4.45Å; L39-K43 HydrophobicContact CG-CD 4.25Å; L39-K43 VanDerWaalsContact O-CB 3.27Å; L39-K43 WeakPolarHBondContact O-CB 3.21Å; L39-K43 WeakPolarHBondContact O-CD 3.2Å; L39-K43 WeakPolarHBondContact O-CG 3.27Å; L39-K43 PolarHBondContact O-N 3.32Å; A40-K43 WeakPolarHBondContact O-CB 3.28Å; A40-K43 PolarHBondContact O-N 3.01Å; A41-K43 PolarHBondContact O-N 3.29Å; K43-C46 CarbonylContact O-C 3.59Å; K43-C46 PolarHBondContact O-N 2.95Å; K43-L47 PolarHBondContact O-N 2.73Å; K43-Q55 PolarHBondContact O-NE2 2.94Å; K43-Q55 PolarHBondContact O-OE1 2.92Å; K43-I58 WeakPolarHBondContact CE-O 3.16Å; K43-I58 PolarHBondContact NZ-O 2.83Å
44F90.2Very high85.1Confident6 Ų650 Ų503%0.02627%0.267CS..Hα-helixtrans-59.3-49.7179.6-178.4-92.8000112.3A40 A41 C46 L47 L125 F126 L160 F163 V164A40-F44 PolarHBondContact O-N 3.32Å; A41-F44 PolarHBondContact O-N 2.86Å; F44-C46 PolarHBondContact O-N 3.3Å; F44-L47 HydrophobicContact CD2-CD1 3.68Å; F44-L47 HydrophobicContact CE2-CD1 4.14Å; F44-L47 HydrophobicContact CG-CD1 4.24Å; F44-L47 WeakPolarHBondContact O-CB 3.26Å; F44-L47 WeakPolarHBondContact O-CD1 3.07Å; F44-L47 WeakPolarHBondContact O-CG 3.43Å; F44-L47 PolarHBondContact O-N 2.68Å; F44-L47 VanDerWaalsContact O-N 3.12Å; F44-L125 HydrophobicContact CE1-CB 3.86Å; F44-L125 HydrophobicContact CZ-CB 3.65Å; F44-L125 HydrophobicContact CZ-CD1 3.91Å; F44-L125 HydrophobicContact CZ-CG 4.46Å; F44-F126 HydrophobicContact CD1-CB 4.34Å; F44-F126 HydrophobicContact CE1-CB 4.35Å; F44-L160 HydrophobicContact CB-CB 4.49Å; F44-L160 HydrophobicContact CB-CD1 4.03Å; F44-L160 HydrophobicContact CB-CD2 4.41Å; F44-L160 HydrophobicContact CD1-CD2 3.72Å; F44-L160 HydrophobicContact CD2-CB 3.9Å; F44-L160 HydrophobicContact CD2-CD2 3.87Å; F44-L160 HydrophobicContact CD2-CG 4.37Å; F44-L160 HydrophobicContact CE1-CD2 3.87Å; F44-L160 HydrophobicContact CE2-CB 4.41Å; F44-L160 HydrophobicContact CE2-CD2 4.01Å; F44-L160 HydrophobicContact CG-CB 4.24Å; F44-L160 HydrophobicContact CG-CD1 4.25Å; F44-L160 HydrophobicContact CG-CD2 3.72Å; F44-L160 HydrophobicContact CG-CG 4.29Å; F44-L160 HydrophobicContact CZ-CD2 4.01Å; F44-F163 HydrophobicContact CE2-CB 4.16Å; F44-F163 HydrophobicContact CZ-CB 4.45Å; F44-F163 HydrophobicContact CZ-CD2 4.37Å; F44-V164 HydrophobicContact CD2-CG2 3.91Å; F44-V164 HydrophobicContact CE2-CG2 3.98Å
45L88.2Confident84.6Confident1 Ų149.8 Ų49.81%0.00527%0.266CS..Hα-helixtrans-61.9-30.9177.8-65.8172.9000112.4A41 L42 L85 H88 I89 I118 R122 F126A41-L45 WeakPolarHBondContact O-CG 3.34Å; A41-L45 PolarHBondContact O-N 3.26Å; L42-L45 PolarHBondContact O-N 2.69Å; L45-L85 HydrophobicContact CB-CD2 3.73Å; L45-L85 HydrophobicContact CD1-CD2 4.19Å; L45-H88 HydrophobicContact CD1-CB 3.82Å; L45-I89 HydrophobicContact CD1-CG2 3.96Å; L45-I118 HydrophobicContact CB-CD1 4.35Å; L45-I118 HydrophobicContact CB-CG2 4.41Å; L45-I118 HydrophobicContact CD2-CG2 4.21Å; L45-R122 HydrophobicContact CD2-CB 4.37Å; L45-F126 HydrophobicContact CD2-CB 3.84Å; L45-F126 HydrophobicContact CD2-CG 4.17Å
46C89Confident84Confident0 Ų054 Ų540%028%0.276CS..THydrogen-bonded Turntrans-83.22.6176.8-66.10000115.2L42 K43 F44 D48 Y49 I50L42-C46 VanDerWaalsContact O-CB 3.29Å; L42-C46 WeakPolarHBondContact O-CB 3.44Å; L42-C46 PolarHBondContact O-N 3.42Å; L42-C46 PolarHBondContact O-SG 3.03Å; K43-C46 CarbonylContact O-C 3.59Å; K43-C46 PolarHBondContact O-N 2.95Å; F44-C46 PolarHBondContact O-N 3.3Å; C46-D48 VanDerWaalsContact C-N 3.27Å; C46-D48 PolarHBondContact O-N 2.76Å; C46-Y49 PolarHBondContact O-N 2.98Å; C46-I50 PolarHBondContact O-N 3.21Å
47L86.3Confident83.8Confident18 Ų1852.6 Ų52.69%0.09426%0.263CS..THydrogen-bonded Turntrans-60-33.4-172.3-83.4167.3000114.4K43 F44 Y49 I50 H52 V164K43-L47 PolarHBondContact O-N 2.73Å; F44-L47 HydrophobicContact CD2-CD1 3.68Å; F44-L47 HydrophobicContact CE2-CD1 4.14Å; F44-L47 HydrophobicContact CG-CD1 4.24Å; F44-L47 WeakPolarHBondContact O-CB 3.26Å; F44-L47 WeakPolarHBondContact O-CD1 3.07Å; F44-L47 WeakPolarHBondContact O-CG 3.43Å; F44-L47 PolarHBondContact O-N 2.68Å; F44-L47 VanDerWaalsContact O-N 3.12Å; L47-Y49 PolarHBondContact O-N 3.38Å; L47-I50 CarbonylContact O-C 3.55Å; L47-H52 HydrophobicContact CD2-CB 4.06Å; L47-V164 HydrophobicContact CD1-CG2 3.46Å; L47-V164 VanDerWaalsContact CD1-CG2 3.46Å
48D84.8Confident83.8Confident76 Ų7644.8 Ų44.841%0.40623%0.227SC..THydrogen-bonded Turntrans-70-24.4-180-58.5-18.9000111.6C46 S119 R122C46-D48 VanDerWaalsContact C-N 3.27Å; C46-D48 PolarHBondContact O-N 2.76Å; D48-S119 WeakPolarHBondContact OD2-CB 3.4Å; D48-S119 PolarHBondContact OD2-OG 3.21Å; D48-R122 IonicContact OD1-CZ 3.28Å; D48-R122 VanDerWaalsContact OD1-CZ 3.28Å; D48-R122 IonicContact OD1-NE 2.76Å; D48-R122 PolarHBondContact OD1-NE 3.48Å; D48-R122 IonicContact OD1-NH2 2.79Å; D48-R122 PolarHBondContact OD1-NH2 2.97Å; D48-R122 WeakPolarHBondContact OD2-CG 3.45Å; D48-R122 IonicContact OD2-NE 2.95Å
49Y83.8Confident83.6Confident74 Ų7450.3 Ų50.329%0.2925%0.251SS..THydrogen-bonded Turntrans-100-36.6-179.5-66.4-75.6000113.7C46 L47 M73 F81 Q117C46-Y49 PolarHBondContact O-N 2.98Å; L47-Y49 PolarHBondContact O-N 3.38Å; Y49-M73 HydrophobicContact CD1-CG 4.36Å; Y49-M73 HydrophobicContact CD1-SD 3.51Å; Y49-M73 VanDerWaalsContact CD1-SD 3.51Å; Y49-M73 HydrophobicContact CE1-SD 3.55Å; Y49-M73 VanDerWaalsContact CE1-SD 3.55Å; Y49-M73 HydrophobicContact CG-SD 4.28Å; Y49-F81 HydrophobicContact CD2-CE2 4.02Å; Y49-F81 AromaticContact CD2-CZ 3.77Å; Y49-F81 HydrophobicContact CD2-CZ 3.77Å; Y49-F81 AromaticContact CE2-CE2 3.78Å; Y49-F81 HydrophobicContact CE2-CE2 3.78Å; Y49-F81 HydrophobicContact CE2-CZ 4.04Å; Y49-F81 HydrophobicContact CG-CZ 4.47Å; Y49-Q117 PolarHBondContact OH-O 3.23Å
50I83.3Confident83.6Confident6 Ų652 Ų523%0.03126%0.26CS..SBendtrans-124.799.4178.7-54.8177.3000107.9C46 L47 K54 Q55 I58 L64 R67 L68C46-I50 PolarHBondContact O-N 3.21Å; L47-I50 CarbonylContact O-C 3.55Å; I50-K54 HydrophobicContact CG2-CB 3.93Å; I50-Q55 HydrophobicContact CB-CG 4.19Å; I50-Q55 HydrophobicContact CG2-CG 3.64Å; I50-Q55 WeakPolarHBondContact O-CG 3.15Å; I50-Q55 PolarHBondContact O-NE2 3.39Å; I50-I58 HydrophobicContact CG2-CD1 4.38Å; I50-L64 HydrophobicContact CD1-CD1 3.97Å; I50-R67 HydrophobicContact CD1-CB 3.85Å; I50-L68 HydrophobicContact CD1-CD2 3.63Å; I50-L68 HydrophobicContact CD1-CG 3.88Å; I50-L68 HydrophobicContact CG1-CD2 4.21Å
51P79.9Confident83.6Confident75 Ų7550.2 Ų50.249%0.48725%0.246SC..  trans-59142.5-179.6-26.434.6000112.6K53 K54 Q55P51-K53 PolarHBondContact O-N 3.24Å; P51-K54 PolarHBondContact O-N 2.66Å; P51-Q55 PolarHBondContact O-N 3.41Å
52H76Confident83.4Confident62 Ų6253.6 Ų53.629%0.28726%0.26SS..Hα-helixtrans-34.6-48.3-179.2-174.3-78.9000115.2L47 K54 Q55 E56 V164 K168L47-H52 HydrophobicContact CD2-CB 4.06Å; H52-K54 PolarHBondContact O-N 2.65Å; H52-K54 VanDerWaalsContact O-N 3.09Å; H52-Q55 CarbonylContact O-C 3.14Å; H52-Q55 WeakPolarHBondContact O-CA 3.45Å; H52-Q55 WeakPolarHBondContact O-CB 3.44Å; H52-Q55 PolarHBondContact O-N 3.07Å; H52-E56 IonicContact CE1-OE1 2.74Å; H52-E56 PolarHBondContact CE1-OE1 2.75Å; H52-E56 VanDerWaalsContact CE1-OE1 3.24Å; H52-E56 IonicContact CG-OE1 2.66Å; H52-E56 IonicContact ND1-OE1 2.66Å; H52-E56 PolarHBondContact ND1-OE1 3.2Å; H52-E56 PolarHBondContact O-N 2.92Å; H52-V164 VanDerWaalsContact CD2-CG1 3.45Å; H52-V164 WeakPolarHBondContact CD2-CG1 3.39Å; H52-K168 PolarHBondContact CE1-NZ 3.45Å; H52-K168 PolarHBondContact NE2-NZ 3.48Å
53K73.4Confident83.3Confident141 Ų14157.1 Ų57.161%0.61328%0.275SS*.Hα-helixtrans-60.6-21.2-179.2-61.4-164.3175.7-156.30115.1P51 E56P51-K53 PolarHBondContact O-N 3.24Å; K53-E56 WeakPolarHBondContact CA-OE1 3.47Å
54K76.8Confident83.3Confident124 Ų12454.9 Ų54.954%0.53927%0.266SS..Hα-helixtrans-91.7-26.2172-66.4-169.8174.8-170.40111.7I50 P51 H52 T57 R67I50-K54 HydrophobicContact CG2-CB 3.93Å; P51-K54 PolarHBondContact O-N 2.66Å; H52-K54 PolarHBondContact O-N 2.65Å; H52-K54 VanDerWaalsContact O-N 3.09Å; K54-T57 PolarHBondContact O-N 2.97Å; K54-T57 PolarHBondContact O-OG1 3.47Å; K54-R67 PolarHBondContact O-NH1 3.49Å; K54-R67 VanDerWaalsContact O-NH1 3.09Å
55Q78.4Confident83.3Confident13 Ų1354.8 Ų54.86%0.06127%0.265CS..Hα-helixtrans-73.4-26.2174.5-55.7-171-7.600113.3K43 I50 P51 H52 T57 I58K43-Q55 PolarHBondContact O-NE2 2.94Å; K43-Q55 PolarHBondContact O-OE1 2.92Å; I50-Q55 HydrophobicContact CB-CG 4.19Å; I50-Q55 HydrophobicContact CG2-CG 3.64Å; I50-Q55 WeakPolarHBondContact O-CG 3.15Å; I50-Q55 PolarHBondContact O-NE2 3.39Å; P51-Q55 PolarHBondContact O-N 3.41Å; H52-Q55 CarbonylContact O-C 3.14Å; H52-Q55 WeakPolarHBondContact O-CA 3.45Å; H52-Q55 WeakPolarHBondContact O-CB 3.44Å; H52-Q55 PolarHBondContact O-N 3.07Å; Q55-T57 PolarHBondContact O-N 2.82Å; Q55-T57 VanDerWaalsContact O-N 3.1Å; Q55-I58 HydrophobicContact CB-CD1 4.46Å; Q55-I58 HydrophobicContact CG-CD1 4.46Å; Q55-I58 WeakPolarHBondContact O-CB 3.45Å; Q55-I58 PolarHBondContact O-N 3.47Å
56E74.9Confident83.1Confident126 Ų12658.8 Ų58.859%0.58929%0.286SS*.THydrogen-bonded Turntrans-54.5-25.8170.7-72.8162.1-142.100112.9H52 K53H52-E56 IonicContact CE1-OE1 2.74Å; H52-E56 PolarHBondContact CE1-OE1 2.75Å; H52-E56 VanDerWaalsContact CE1-OE1 3.24Å; H52-E56 IonicContact CG-OE1 2.66Å; H52-E56 IonicContact ND1-OE1 2.66Å; H52-E56 PolarHBondContact ND1-OE1 3.2Å; H52-E56 PolarHBondContact O-N 2.92Å; K53-E56 WeakPolarHBondContact CA-OE1 3.47Å
57T79.1Confident82.9Confident73 Ų7362.1 Ų62.145%0.44830%0.299SS..THydrogen-bonded Turntrans-91.42.3176.365.40000114.4K54 Q55 R67K54-T57 PolarHBondContact O-N 2.97Å; K54-T57 PolarHBondContact O-OG1 3.47Å; Q55-T57 PolarHBondContact O-N 2.82Å; Q55-T57 VanDerWaalsContact O-N 3.1Å; T57-R67 PolarHBondContact OG1-NH1 3.2Å; T57-R67 PolarHBondContact OG1-NH2 2.85Å
58I85.1Confident82.9Confident3 Ų361.3 Ų61.32%0.01529%0.294CS..  trans-101.998.9-176.8-59.5178.6000107.4K43 I50 Q55 D60 K63 L64 R67K43-I58 WeakPolarHBondContact CE-O 3.16Å; K43-I58 PolarHBondContact NZ-O 2.83Å; I50-I58 HydrophobicContact CG2-CD1 4.38Å; Q55-I58 HydrophobicContact CB-CD1 4.46Å; Q55-I58 HydrophobicContact CG-CD1 4.46Å; Q55-I58 WeakPolarHBondContact O-CB 3.45Å; Q55-I58 PolarHBondContact O-N 3.47Å; I58-D60 WeakPolarHBondContact CG2-O 3.33Å; I58-K63 HydrophobicContact CG2-CB 4Å; I58-L64 HydrophobicContact CD1-CD1 3.78Å; I58-L64 HydrophobicContact CG2-CB 3.77Å; I58-L64 HydrophobicContact CG2-CD1 4.4Å; I58-R67 HydrophobicContact CD1-CB 4.25Å; I58-R67 HydrophobicContact CD1-CG 4.05Å; I58-R67 HydrophobicContact CG1-CG 4.38Å
59E83.8Confident82.9Confident147 Ų14761.8 Ų61.869%0.68729%0.291SS*.  trans-87.8-20.6-177.2-64.6162.1166.500112.5L39 K63L39-E59 WeakPolarHBondContact CD2-O 3.18Å; E59-K63 HydrophobicContact CB-CD 4.4Å; E59-K63 IonicContact OE2-NZ 3.28Å; E59-K63 PolarHBondContact OE2-NZ 3.41Å
60D87.2Confident82.9Confident48 Ų4864.8 Ų64.826%0.25731%0.307SS..SBendtrans-145.4165.4-171.955.768.1000111.5I58 Q62 K63 L64I58-D60 WeakPolarHBondContact CG2-O 3.33Å; D60-Q62 VanDerWaalsContact C-N 3.3Å; D60-Q62 PolarHBondContact O-N 3.29Å; D60-Q62 WeakPolarHBondContact OD1-CB 3.45Å; D60-Q62 PolarHBondContact OD1-N 3.12Å; D60-K63 PolarHBondContact O-N 2.67Å; D60-K63 WeakPolarHBondContact OD1-CB 3.38Å; D60-K63 WeakPolarHBondContact OD1-CG 3.36Å; D60-K63 PolarHBondContact OD1-N 3.18Å; D60-K63 WeakPolarHBondContact OD2-CD 3.44Å; D60-K63 WeakPolarHBondContact OD2-CE 3.45Å; D60-K63 IonicContact OD2-NZ 2.7Å; D60-K63 PolarHBondContact OD2-NZ 3.06Å; D60-L64 PolarHBondContact O-N 3.4Å
61A87.9Confident82.9Confident6 Ų670.1 Ų70.15%0.0533%0.33CS..Hα-helixtrans-67.6-27.6-179.900000113.2A31 L34 L39 L64 F65A31-A61 HydrophobicContact CB-CB 3.81Å; L34-A61 HydrophobicContact CB-CB 4.11Å; L34-A61 HydrophobicContact CD1-CB 3.98Å; L39-A61 HydrophobicContact CD1-CB 4.33Å; A61-L64 WeakPolarHBondContact O-CB 3.44Å; A61-L64 PolarHBondContact O-N 3.01Å; A61-L64 VanDerWaalsContact O-N 3.17Å; A61-F65 WeakPolarHBondContact O-CG 3.42Å; A61-F65 PolarHBondContact O-N 2.74Å
62Q85.8Confident83Confident80 Ų8068 Ų6837%0.37432%0.323SS..Hα-helixtrans-65.8-44.4177.5-55.7175.628.100111Y28 A31 E32 D60 L64 F65 L66Y28-Q62 HydrophobicContact CD2-CG 4.43Å; A31-Q62 HydrophobicContact CB-CB 4.37Å; A31-Q62 HydrophobicContact CB-CG 3.47Å; A31-Q62 VanDerWaalsContact CB-CG 3.47Å; E32-Q62 PolarHBondContact OE1-NE2 3.45Å; D60-Q62 VanDerWaalsContact C-N 3.3Å; D60-Q62 PolarHBondContact O-N 3.29Å; D60-Q62 WeakPolarHBondContact OD1-CB 3.45Å; D60-Q62 PolarHBondContact OD1-N 3.12Å; Q62-L64 VanDerWaalsContact C-N 3.28Å; Q62-L64 PolarHBondContact O-N 3.04Å; Q62-F65 PolarHBondContact O-N 3.23Å; Q62-L66 WeakPolarHBondContact O-CB 3.37Å; Q62-L66 PolarHBondContact O-N 2.9Å
63K87.3Confident83.2Confident73 Ų7367.2 Ų67.232%0.31732%0.32SS..Hα-helixtrans-61.9-34.4171.8-74.3172.3-172.5136.20111.7I58 E59 D60 R67I58-K63 HydrophobicContact CG2-CB 4Å; E59-K63 HydrophobicContact CB-CD 4.4Å; E59-K63 IonicContact OE2-NZ 3.28Å; E59-K63 PolarHBondContact OE2-NZ 3.41Å; D60-K63 PolarHBondContact O-N 2.67Å; D60-K63 WeakPolarHBondContact OD1-CB 3.38Å; D60-K63 WeakPolarHBondContact OD1-CG 3.36Å; D60-K63 PolarHBondContact OD1-N 3.18Å; D60-K63 WeakPolarHBondContact OD2-CD 3.44Å; D60-K63 WeakPolarHBondContact OD2-CE 3.45Å; D60-K63 IonicContact OD2-NZ 2.7Å; D60-K63 PolarHBondContact OD2-NZ 3.06Å; K63-R67 VanDerWaalsContact O-CG 3.23Å; K63-R67 WeakPolarHBondContact O-CG 3.49Å; K63-R67 PolarHBondContact O-N 2.93Å; K63-R67 VanDerWaalsContact O-N 3.12Å
64L88.8Confident83.7Confident0 Ų060.7 Ų60.70%029%0.291CS..Hα-helixtrans-65.7-50.5175.1-173.759.1000111L39 L42 I50 I58 D60 A61 Q62 L66 R67 L68L39-L64 HydrophobicContact CD1-CB 4.31Å; L39-L64 HydrophobicContact CD1-CD2 4.07Å; L42-L64 HydrophobicContact CB-CD2 3.61Å; L42-L64 HydrophobicContact CD1-CD2 4.47Å; I50-L64 HydrophobicContact CD1-CD1 3.97Å; I58-L64 HydrophobicContact CD1-CD1 3.78Å; I58-L64 HydrophobicContact CG2-CB 3.77Å; I58-L64 HydrophobicContact CG2-CD1 4.4Å; D60-L64 PolarHBondContact O-N 3.4Å; A61-L64 WeakPolarHBondContact O-CB 3.44Å; A61-L64 PolarHBondContact O-N 3.01Å; A61-L64 VanDerWaalsContact O-N 3.17Å; Q62-L64 VanDerWaalsContact C-N 3.28Å; Q62-L64 PolarHBondContact O-N 3.04Å; L64-L66 VanDerWaalsContact C-N 3.33Å; L64-L66 PolarHBondContact O-N 3.32Å; L64-R67 PolarHBondContact O-N 3.13Å; L64-R67 VanDerWaalsContact O-N 3.13Å; L64-L68 HydrophobicContact CG-CD1 4.26Å; L64-L68 WeakPolarHBondContact O-CG 3.26Å; L64-L68 PolarHBondContact O-N 3.2Å
65F88.8Confident84Confident4 Ų460 Ų602%0.01829%0.29CS..Hα-helixtrans-62.7-38.7178.3-61.2-22.8000112.2L27 I30 A31 L34 A61 Q62 R67 L68 R69 L74 L82L27-F65 HydrophobicContact CB-CD2 4.15Å; L27-F65 HydrophobicContact CD2-CB 4.46Å; L27-F65 HydrophobicContact CD2-CD2 4.02Å; L27-F65 HydrophobicContact CD2-CE2 4.48Å; L27-F65 HydrophobicContact CD2-CG 4.25Å; I30-F65 HydrophobicContact CB-CE2 4.23Å; I30-F65 HydrophobicContact CG2-CE2 3.82Å; I30-F65 HydrophobicContact CG2-CZ 3.8Å; A31-F65 HydrophobicContact CB-CD2 4.06Å; A31-F65 HydrophobicContact CB-CE2 3.83Å; L34-F65 HydrophobicContact CD1-CE2 4.23Å; L34-F65 HydrophobicContact CD1-CZ 3.6Å; A61-F65 WeakPolarHBondContact O-CG 3.42Å; A61-F65 PolarHBondContact O-N 2.74Å; Q62-F65 PolarHBondContact O-N 3.23Å; F65-R67 VanDerWaalsContact C-N 3.34Å; F65-R67 PolarHBondContact O-N 3.05Å; F65-L68 HydrophobicContact CD1-CD1 4.46Å; F65-L68 PolarHBondContact O-N 3.35Å; F65-R69 WeakPolarHBondContact O-CG 3.34Å; F65-R69 PolarHBondContact O-N 3.25Å; F65-L74 HydrophobicContact CB-CD1 4.1Å; F65-L74 HydrophobicContact CD1-CD1 4.09Å; F65-L74 HydrophobicContact CG-CD1 4.35Å; F65-L82 HydrophobicContact CD1-CD1 4.31Å; F65-L82 HydrophobicContact CE1-CD1 3.56Å; F65-L82 HydrophobicContact CZ-CD1 3.78Å
66L85.1Confident83.7Confident86 Ų8666.2 Ų66.245%0.4532%0.319SS..Hα-helixtrans-58.8-43.7172.8-176.563.4000112Q62 L64 R69 E70Q62-L66 WeakPolarHBondContact O-CB 3.37Å; Q62-L66 PolarHBondContact O-N 2.9Å; L64-L66 VanDerWaalsContact C-N 3.33Å; L64-L66 PolarHBondContact O-N 3.32Å; L66-R69 WeakPolarHBondContact O-CB 3.4Å; L66-R69 PolarHBondContact O-N 3.37Å; L66-E70 WeakPolarHBondContact O-CG 3.43Å; L66-E70 PolarHBondContact O-N 3.18Å
67R85.1Confident83.5Confident70 Ų7064.2 Ų64.226%0.26433%0.332SS..Hα-helixtrans-70.7-30.6178.3-69.3-69.9-175.466.45.3113.6I50 K54 T57 I58 K63 L64 F65 E70 K71I50-R67 HydrophobicContact CD1-CB 3.85Å; K54-R67 PolarHBondContact O-NH1 3.49Å; K54-R67 VanDerWaalsContact O-NH1 3.09Å; T57-R67 PolarHBondContact OG1-NH1 3.2Å; T57-R67 PolarHBondContact OG1-NH2 2.85Å; I58-R67 HydrophobicContact CD1-CB 4.25Å; I58-R67 HydrophobicContact CD1-CG 4.05Å; I58-R67 HydrophobicContact CG1-CG 4.38Å; K63-R67 VanDerWaalsContact O-CG 3.23Å; K63-R67 WeakPolarHBondContact O-CG 3.49Å; K63-R67 PolarHBondContact O-N 2.93Å; K63-R67 VanDerWaalsContact O-N 3.12Å; L64-R67 PolarHBondContact O-N 3.13Å; L64-R67 VanDerWaalsContact O-N 3.13Å; F65-R67 VanDerWaalsContact C-N 3.34Å; F65-R67 PolarHBondContact O-N 3.05Å; R67-E70 VanDerWaalsContact CD-OE2 3.26Å; R67-E70 WeakPolarHBondContact CD-OE2 3.48Å; R67-E70 IonicContact NE-OE2 2.78Å; R67-K71 WeakPolarHBondContact O-CG 3.32Å; R67-K71 PolarHBondContact O-N 2.8Å
68L86.1Confident83.5Confident0 Ų063.9 Ų63.90%033%0.327CS..Hα-helixtrans-71.9-34.3172.1-71.4172.3000112I50 L64 F65 K71 G72 M73 L74 F81 L85I50-L68 HydrophobicContact CD1-CD2 3.63Å; I50-L68 HydrophobicContact CD1-CG 3.88Å; I50-L68 HydrophobicContact CG1-CD2 4.21Å; L64-L68 HydrophobicContact CG-CD1 4.26Å; L64-L68 WeakPolarHBondContact O-CG 3.26Å; L64-L68 PolarHBondContact O-N 3.2Å; F65-L68 HydrophobicContact CD1-CD1 4.46Å; F65-L68 PolarHBondContact O-N 3.35Å; L68-K71 CarbonylContact O-C 3.58Å; L68-K71 WeakPolarHBondContact O-CB 3.4Å; L68-K71 PolarHBondContact O-N 3.16Å; L68-G72 PolarHBondContact O-N 3.17Å; L68-M73 HydrophobicContact CD2-CB 4.33Å; L68-M73 PolarHBondContact O-N 3.04Å; L68-L74 HydrophobicContact CB-CD1 3.62Å; L68-L74 HydrophobicContact CB-CG 3.82Å; L68-L74 HydrophobicContact CD1-CD1 4.03Å; L68-L74 HydrophobicContact CG-CD1 4.5Å; L68-F81 HydrophobicContact CD1-CD1 4.37Å; L68-F81 HydrophobicContact CD1-CE1 4.05Å; L68-F81 HydrophobicContact CD2-CD1 4.33Å; L68-F81 HydrophobicContact CD2-CE1 3.65Å; L68-F81 HydrophobicContact CG-CE1 4.48Å; L68-L85 HydrophobicContact CD1-CD1 4.08Å
69R84.6Confident83.4Confident87 Ų8765.7 Ų65.733%0.32834%0.337SS..Hα-helixtrans-65.6-45.6170.2-71.6178.463.6-178.16.2112.7F23 F65 L66 K71 G72 L74F23-R69 HydrophobicContact CE1-CG 4.47Å; F23-R69 HydrophobicContact CZ-CG 4.43Å; F65-R69 WeakPolarHBondContact O-CG 3.34Å; F65-R69 PolarHBondContact O-N 3.25Å; L66-R69 WeakPolarHBondContact O-CB 3.4Å; L66-R69 PolarHBondContact O-N 3.37Å; R69-K71 PolarHBondContact O-N 3.28Å; R69-G72 PolarHBondContact O-N 3.09Å; R69-L74 HydrophobicContact CG-CB 3.78Å; R69-L74 WeakPolarHBondContact CG-O 3.32Å
70E84.2Confident83.4Confident136 Ų13660.7 Ų60.764%0.63632%0.318SS*.THydrogen-bonded Turntrans-56.6-20.2172.5-74.8177-172.500113L66 R67L66-E70 WeakPolarHBondContact O-CG 3.43Å; L66-E70 PolarHBondContact O-N 3.18Å; R67-E70 VanDerWaalsContact CD-OE2 3.26Å; R67-E70 WeakPolarHBondContact CD-OE2 3.48Å; R67-E70 IonicContact NE-OE2 2.78Å
71K82.2Confident83.4Confident118 Ų11858.4 Ų58.451%0.51331%0.306SS..THydrogen-bonded Turntrans-96.4-2.8178.4-81.2-75.1-176.31710114.8R67 L68 R69 M73R67-K71 WeakPolarHBondContact O-CG 3.32Å; R67-K71 PolarHBondContact O-N 2.8Å; L68-K71 CarbonylContact O-C 3.58Å; L68-K71 WeakPolarHBondContact O-CB 3.4Å; L68-K71 PolarHBondContact O-N 3.16Å; R69-K71 PolarHBondContact O-N 3.28Å; K71-M73 HydrophobicContact CB-CG 4.01Å; K71-M73 PolarHBondContact O-N 3.18Å
72G81.8Confident83.3Confident32 Ų3258.1 Ų58.133%0.3330%0.304SS..THydrogen-bonded Turntrans70.217-175.500000114.2L68 R69L68-G72 PolarHBondContact O-N 3.17Å; R69-G72 PolarHBondContact O-N 3.09Å
73M81Confident83.4Confident45 Ų4556.5 Ų56.522%0.22230%0.295CS..SBendtrans-93.2-11.1179.3-54.8-8070.500112.7Y49 L68 K71 F81Y49-M73 HydrophobicContact CD1-CG 4.36Å; Y49-M73 HydrophobicContact CD1-SD 3.51Å; Y49-M73 VanDerWaalsContact CD1-SD 3.51Å; Y49-M73 HydrophobicContact CE1-SD 3.55Å; Y49-M73 VanDerWaalsContact CE1-SD 3.55Å; Y49-M73 HydrophobicContact CG-SD 4.28Å; L68-M73 HydrophobicContact CD2-CB 4.33Å; L68-M73 PolarHBondContact O-N 3.04Å; K71-M73 HydrophobicContact CB-CG 4.01Å; K71-M73 PolarHBondContact O-N 3.18Å; M73-F81 HydrophobicContact CB-CD1 4.03Å; M73-F81 HydrophobicContact CB-CE1 4.43Å; M73-F81 HydrophobicContact CB-CG 4.43Å; M73-F81 WeakPolarHBondContact O-CB 3.37Å
74L83.8Confident83.4Confident3 Ų353.1 Ų53.12%0.01628%0.281CS..  trans-133.9118.4173.8-65.9-180000109.3L27 F65 L68 R69 L82L27-L74 HydrophobicContact CD2-CD1 4.44Å; F65-L74 HydrophobicContact CB-CD1 4.1Å; F65-L74 HydrophobicContact CD1-CD1 4.09Å; F65-L74 HydrophobicContact CG-CD1 4.35Å; L68-L74 HydrophobicContact CB-CD1 3.62Å; L68-L74 HydrophobicContact CB-CG 3.82Å; L68-L74 HydrophobicContact CD1-CD1 4.03Å; L68-L74 HydrophobicContact CG-CD1 4.5Å; R69-L74 HydrophobicContact CG-CB 3.78Å; R69-L74 WeakPolarHBondContact CG-O 3.32Å; L74-L82 HydrophobicContact CD2-CB 3.65Å
75E82.3Confident83.4Confident110 Ų11053.1 Ų53.151%0.51428%0.281SS..BIsolated β-bridgetrans-137.4157.9178.3-61.2-171.3164.800110.2F23 G77 N78F23-E75 VanDerWaalsContact CE2-C 3.43Å; F23-E75 WeakPolarHBondContact CE2-O 3.33Å; E75-G77 PolarHBondContact O-N 2.95Å; E75-G77 VanDerWaalsContact O-N 3.15Å; E75-N78 HydrophobicContact CB-CB 4.41Å; E75-N78 PolarHBondContact N-O 2.93Å; E75-N78 VanDerWaalsContact N-O 3.16Å; E75-N78 CarbonylContact O-C 3.58Å; E75-N78 VanDerWaalsContact O-C 3.31Å; E75-N78 PolarHBondContact O-N 3.02Å; E75-N78 VanDerWaalsContact O-O 3.05Å
76E73.8Confident83.3Confident144 Ų14452.9 Ų52.967%0.67328%0.28SS*.THydrogen-bonded Turntrans-59.4-29.2-177.4-178.5173.6-176.700113.2F23F23-E76 HydrophobicContact CB-CB 4.24Å; F23-E76 HydrophobicContact CB-CG 4.01Å; F23-E76 HydrophobicContact CD1-CB 4.37Å; F23-E76 HydrophobicContact CD2-CB 4.2Å; F23-E76 HydrophobicContact CG-CB 4.05Å; F23-E76 HydrophobicContact CG-CG 4.35Å
77G70.7Confident83.4Confident84 Ų8450.3 Ų50.387%0.86627%0.265SS*.THydrogen-bonded Turntrans-94.1-6173.400000115.2E75E75-G77 PolarHBondContact O-N 2.95Å; E75-G77 VanDerWaalsContact O-N 3.15Å
78N78.9Confident83.4Confident65 Ų6548.2 Ų48.235%0.34826%0.258SS..BIsolated β-bridgetrans-140.399.5-175.7-171.59.5000112.1E75 S80E75-N78 HydrophobicContact CB-CB 4.41Å; E75-N78 PolarHBondContact N-O 2.93Å; E75-N78 VanDerWaalsContact N-O 3.16Å; E75-N78 CarbonylContact O-C 3.58Å; E75-N78 VanDerWaalsContact O-C 3.31Å; E75-N78 PolarHBondContact O-N 3.02Å; E75-N78 VanDerWaalsContact O-O 3.05Å; N78-S80 WeakPolarHBondContact OD1-CB 3.39Å; N78-S80 PolarHBondContact OD1-N 3.12Å; N78-S80 PolarHBondContact OD1-OG 3.15Å
79L82.3Confident83.5Confident42 Ų4249 Ų4922%0.2226%0.262CS..  trans-109.79.1177.8-69.7169.7000112.7F23 F81 L82 K83 L99F23-L79 HydrophobicContact CD2-CD2 4.29Å; F23-L79 HydrophobicContact CE2-CD2 3.71Å; L79-F81 VanDerWaalsContact C-N 3.35Å; L79-F81 PolarHBondContact O-N 3.04Å; L79-L82 HydrophobicContact CD2-CD2 4.17Å; L79-L82 PolarHBondContact O-N 3.26Å; L79-L82 VanDerWaalsContact O-N 3.11Å; L79-K83 WeakPolarHBondContact O-CG 3.17Å; L79-K83 PolarHBondContact O-N 3.41Å; L79-L99 HydrophobicContact CD1-CD2 3.86Å
80S84.1Confident83.5Confident42 Ų4248.3 Ų48.329%0.29427%0.271SS..Hα-helixtrans-55.1-46.6-17755.50000112.5N78 L82 K83 E84 Q117N78-S80 WeakPolarHBondContact OD1-CB 3.39Å; N78-S80 PolarHBondContact OD1-N 3.12Å; N78-S80 PolarHBondContact OD1-OG 3.15Å; S80-L82 PolarHBondContact O-N 2.99Å; S80-K83 WeakPolarHBondContact O-CB 3.24Å; S80-K83 PolarHBondContact O-N 2.96Å; S80-E84 PolarHBondContact O-N 3.47Å; S80-Q117 PolarHBondContact OG-NE2 3.2Å
81F86.6Confident83.6Confident0 Ų043.6 Ų43.60%025%0.247CC..Hα-helixtrans-60.8-39.9176.5-167.7-111000113.3Y49 L68 M73 L79 E84 L85 Q117 I118Y49-F81 HydrophobicContact CD2-CE2 4.02Å; Y49-F81 AromaticContact CD2-CZ 3.77Å; Y49-F81 HydrophobicContact CD2-CZ 3.77Å; Y49-F81 AromaticContact CE2-CE2 3.78Å; Y49-F81 HydrophobicContact CE2-CE2 3.78Å; Y49-F81 HydrophobicContact CE2-CZ 4.04Å; Y49-F81 HydrophobicContact CG-CZ 4.47Å; L68-F81 HydrophobicContact CD1-CD1 4.37Å; L68-F81 HydrophobicContact CD1-CE1 4.05Å; L68-F81 HydrophobicContact CD2-CD1 4.33Å; L68-F81 HydrophobicContact CD2-CE1 3.65Å; L68-F81 HydrophobicContact CG-CE1 4.48Å; M73-F81 HydrophobicContact CB-CD1 4.03Å; M73-F81 HydrophobicContact CB-CE1 4.43Å; M73-F81 HydrophobicContact CB-CG 4.43Å; M73-F81 WeakPolarHBondContact O-CB 3.37Å; L79-F81 VanDerWaalsContact C-N 3.35Å; L79-F81 PolarHBondContact O-N 3.04Å; F81-E84 PolarHBondContact O-N 3.17Å; F81-L85 HydrophobicContact CD1-CD1 3.74Å; F81-L85 HydrophobicContact CD1-CG 4.38Å; F81-L85 HydrophobicContact CE1-CD1 3.53Å; F81-L85 HydrophobicContact CE1-CG 4.12Å; F81-L85 HydrophobicContact CZ-CD1 4.24Å; F81-L85 HydrophobicContact CZ-CG 4.39Å; F81-L85 WeakPolarHBondContact O-CB 3.49Å; F81-L85 WeakPolarHBondContact O-CG 3.43Å; F81-L85 PolarHBondContact O-N 3.42Å; F81-Q117 HydrophobicContact CD2-CB 3.69Å; F81-Q117 HydrophobicContact CE2-CB 4.16Å; F81-I118 HydrophobicContact CD2-CG1 4.37Å; F81-I118 HydrophobicContact CE2-CG1 3.74Å; F81-I118 HydrophobicContact CZ-CG1 4.38Å
82L87.1Confident83.5Confident0 Ų041.4 Ų41.40%024%0.236CC..Hα-helixtrans-67.5-40.6175.7-173.958.8000111.7L27 I30 F65 L74 L79 S80 L85 L86 L99L27-L82 HydrophobicContact CD2-CD2 3.62Å; I30-L82 HydrophobicContact CD1-CD2 3.92Å; F65-L82 HydrophobicContact CD1-CD1 4.31Å; F65-L82 HydrophobicContact CE1-CD1 3.56Å; F65-L82 HydrophobicContact CZ-CD1 3.78Å; L74-L82 HydrophobicContact CD2-CB 3.65Å; L79-L82 HydrophobicContact CD2-CD2 4.17Å; L79-L82 PolarHBondContact O-N 3.26Å; L79-L82 VanDerWaalsContact O-N 3.11Å; S80-L82 PolarHBondContact O-N 2.99Å; L82-L85 PolarHBondContact O-N 3.34Å; L82-L86 HydrophobicContact CD1-CD1 4.21Å; L82-L86 HydrophobicContact CD1-CG 4.2Å; L82-L86 HydrophobicContact CG-CD1 4.01Å; L82-L86 HydrophobicContact CG-CG 4.4Å; L82-L86 WeakPolarHBondContact O-CB 3.36Å; L82-L86 VanDerWaalsContact O-CG 3.31Å; L82-L86 WeakPolarHBondContact O-CG 3.19Å; L82-L86 PolarHBondContact O-N 3.08Å; L82-L99 HydrophobicContact CD2-CD1 4.09Å; L82-L99 HydrophobicContact CD2-CD2 4.4Å; L82-L99 HydrophobicContact CG-CD1 4.09Å
83K86.3Confident83.4Confident45 Ų4542.9 Ų42.920%0.19624%0.236CC..Hα-helixtrans-62.1-44.4176.3-70.9178.4168.3-160.60110.9L79 S80 F87 L95 L99 C101 M106L79-K83 WeakPolarHBondContact O-CG 3.17Å; L79-K83 PolarHBondContact O-N 3.41Å; S80-K83 WeakPolarHBondContact O-CB 3.24Å; S80-K83 PolarHBondContact O-N 2.96Å; K83-F87 WeakPolarHBondContact O-CB 3.33Å; K83-F87 PolarHBondContact O-N 3.09Å; K83-L95 HydrophobicContact CB-CD2 4.06Å; K83-L95 HydrophobicContact CG-CD2 4.19Å; K83-L99 WeakPolarHBondContact CE-O 3.43Å; K83-L99 HydrophobicContact CG-CB 4.38Å; K83-L99 HydrophobicContact CG-CD1 3.9Å; K83-L99 PolarHBondContact NZ-O 3.17Å; K83-C101 HydrophobicContact CD-CB 4.25Å; K83-M106 HydrophobicContact CB-CE 3.87Å; K83-M106 HydrophobicContact CB-SD 3.76Å; K83-M106 HydrophobicContact CD-SD 4.31Å
84E88.4Confident83.6Confident2 Ų240.8 Ų40.81%0.00923%0.226CC..Hα-helixtrans-63.7-44.1176.3-170.6179.1176.900112.3S80 F81 F87 H88 L110 Q117 I118S80-E84 PolarHBondContact O-N 3.47Å; F81-E84 PolarHBondContact O-N 3.17Å; E84-F87 WeakPolarHBondContact O-CB 3.38Å; E84-F87 PolarHBondContact O-N 3.43Å; E84-H88 PolarHBondContact O-CD2 3.34Å; E84-H88 PolarHBondContact O-N 3.32Å; E84-L110 HydrophobicContact CB-CD2 4.48Å; E84-L110 HydrophobicContact CG-CD1 4.24Å; E84-L110 HydrophobicContact CG-CD2 3.87Å; E84-Q117 PolarHBondContact OE1-N 3.44Å; E84-Q117 WeakPolarHBondContact OE2-CA 3.41Å; E84-Q117 WeakPolarHBondContact OE2-CB 3.46Å; E84-Q117 PolarHBondContact OE2-N 3.38Å; E84-I118 HydrophobicContact CB-CD1 4.4Å; E84-I118 HydrophobicContact CG-CD1 3.89Å; E84-I118 HydrophobicContact CG-CG1 4.04Å; E84-I118 WeakPolarHBondContact OE1-CB 3.46Å; E84-I118 PolarHBondContact OE1-N 2.96Å; E84-I118 PolarHBondContact OE2-N 3.47Å
85L88.3Confident83.5Confident0 Ų040.7 Ų40.70%023%0.225CC..Hα-helixtrans-56.9-53.9173.8-81.9172.1000112.3L42 L45 L68 F81 L82 F87 H88 I89 I118L42-L85 HydrophobicContact CD2-CB 3.66Å; L42-L85 HydrophobicContact CD2-CD1 4.31Å; L42-L85 HydrophobicContact CD2-CD2 3.87Å; L42-L85 HydrophobicContact CD2-CG 4.16Å; L45-L85 HydrophobicContact CB-CD2 3.73Å; L45-L85 HydrophobicContact CD1-CD2 4.19Å; L68-L85 HydrophobicContact CD1-CD1 4.08Å; F81-L85 HydrophobicContact CD1-CD1 3.74Å; F81-L85 HydrophobicContact CD1-CG 4.38Å; F81-L85 HydrophobicContact CE1-CD1 3.53Å; F81-L85 HydrophobicContact CE1-CG 4.12Å; F81-L85 HydrophobicContact CZ-CD1 4.24Å; F81-L85 HydrophobicContact CZ-CG 4.39Å; F81-L85 WeakPolarHBondContact O-CB 3.49Å; F81-L85 WeakPolarHBondContact O-CG 3.43Å; F81-L85 PolarHBondContact O-N 3.42Å; L82-L85 PolarHBondContact O-N 3.34Å; L85-F87 VanDerWaalsContact C-N 3.3Å; L85-F87 PolarHBondContact O-N 2.94Å; L85-H88 PolarHBondContact O-N 3.36Å; L85-I89 PolarHBondContact O-N 2.81Å; L85-I89 VanDerWaalsContact O-N 3.14Å; L85-I118 HydrophobicContact CB-CD1 4.49Å; L85-I118 HydrophobicContact CD2-CD1 3.58Å; L85-I118 HydrophobicContact CG-CD1 3.87Å
86L87.5Confident83.4Confident0 Ų039.6 Ų39.60%023%0.226CC..Hα-helixtrans-65-32.9-179.7-68.2175.7000112.5I30 L34 L82 I89 S90 R91 L94 L95 L99I30-L86 HydrophobicContact CG2-CD1 4.14Å; I30-L86 HydrophobicContact CG2-CD2 4.38Å; L34-L86 HydrophobicContact CD2-CD2 4.1Å; L82-L86 HydrophobicContact CD1-CD1 4.21Å; L82-L86 HydrophobicContact CD1-CG 4.2Å; L82-L86 HydrophobicContact CG-CD1 4.01Å; L82-L86 HydrophobicContact CG-CG 4.4Å; L82-L86 WeakPolarHBondContact O-CB 3.36Å; L82-L86 VanDerWaalsContact O-CG 3.31Å; L82-L86 WeakPolarHBondContact O-CG 3.19Å; L82-L86 PolarHBondContact O-N 3.08Å; L86-I89 HydrophobicContact CD2-CD1 4.05Å; L86-S90 PolarHBondContact O-N 3.38Å; L86-R91 HydrophobicContact CD2-CB 4.23Å; L86-R91 PolarHBondContact O-N 3.1Å; L86-L94 HydrophobicContact CD1-CB 4.06Å; L86-L94 HydrophobicContact CD2-CB 4.41Å; L86-L94 HydrophobicContact CD2-CD1 4.02Å; L86-L95 HydrophobicContact CB-CD2 3.83Å; L86-L95 HydrophobicContact CB-CG 3.91Å; L86-L95 HydrophobicContact CD1-CD2 4.4Å; L86-L99 HydrophobicContact CD1-CD1 3.63Å
87F87.2Confident83.6Confident32 Ų3238.3 Ų38.314%0.1422%0.223CC..Hα-helixtrans-62.9-44.2172.9178.2-80.2000111.6K83 E84 L85 S90 W92 L95 M106 V107 L110K83-F87 WeakPolarHBondContact O-CB 3.33Å; K83-F87 PolarHBondContact O-N 3.09Å; E84-F87 WeakPolarHBondContact O-CB 3.38Å; E84-F87 PolarHBondContact O-N 3.43Å; L85-F87 VanDerWaalsContact C-N 3.3Å; L85-F87 PolarHBondContact O-N 2.94Å; F87-S90 PolarHBondContact O-N 3.44Å; F87-W92 HydrophobicContact CB-CH2 4.46Å; F87-W92 HydrophobicContact CD1-CH2 4.24Å; F87-W92 AromaticContact CD2-CH2 3.3Å; F87-W92 HydrophobicContact CD2-CH2 3.3Å; F87-W92 AromaticContact CD2-CZ3 3.3Å; F87-W92 HydrophobicContact CD2-CZ3 3.3Å; F87-W92 HydrophobicContact CE1-CH2 4.31Å; F87-W92 AromaticContact CE2-CH2 3.41Å; F87-W92 HydrophobicContact CE2-CH2 3.41Å; F87-W92 VanDerWaalsContact CE2-CH2 3.41Å; F87-W92 AromaticContact CE2-CZ3 3.63Å; F87-W92 HydrophobicContact CE2-CZ3 3.63Å; F87-W92 AromaticContact CG-CH2 3.74Å; F87-W92 HydrophobicContact CG-CH2 3.74Å; F87-W92 HydrophobicContact CG-CZ3 4.03Å; F87-W92 AromaticContact CZ-CH2 3.92Å; F87-W92 HydrophobicContact CZ-CH2 3.92Å; F87-L95 HydrophobicContact CB-CD1 4.09Å; F87-M106 HydrophobicContact CB-CE 4.09Å; F87-M106 HydrophobicContact CD2-CB 3.36Å; F87-M106 HydrophobicContact CD2-CE 4.2Å; F87-M106 HydrophobicContact CD2-CG 3.93Å; F87-M106 HydrophobicContact CE2-CB 3.44Å; F87-M106 VanDerWaalsContact CE2-CB 3.44Å; F87-M106 HydrophobicContact CE2-CG 4.47Å; F87-M106 HydrophobicContact CG-CB 4.45Å; F87-M106 HydrophobicContact CG-CE 4.31Å; F87-V107 HydrophobicContact CE2-CG2 3.88Å; F87-V107 HydrophobicContact CZ-CG2 3.78Å; F87-L110 HydrophobicContact CD1-CD1 3.77Å; F87-L110 HydrophobicContact CD2-CD1 4.39Å; F87-L110 HydrophobicContact CE1-CD1 3.85Å; F87-L110 HydrophobicContact CE2-CD1 4.45Å; F87-L110 HydrophobicContact CG-CD1 4.08Å; F87-L110 HydrophobicContact CZ-CD1 4.21Å
88H85.5Confident84Confident26 Ų2637 Ų3712%0.1219%0.194CC..Hα-helixtrans-70.7-40.6-179.1-79.3-55.7000113.2L45 E84 L85 S90 V123 F126L45-H88 HydrophobicContact CD1-CB 3.82Å; E84-H88 PolarHBondContact O-CD2 3.34Å; E84-H88 PolarHBondContact O-N 3.32Å; L85-H88 PolarHBondContact O-N 3.36Å; H88-S90 PolarHBondContact O-N 3.47Å; H88-V123 VanDerWaalsContact CE1-CG1 3.42Å; H88-V123 WeakPolarHBondContact CE1-CG1 3.27Å; H88-F126 VanDerWaalsContact O-CE1 3.32Å; H88-F126 WeakPolarHBondContact O-CE1 3.42Å
89I87.5Confident84Confident15 Ų1534.6 Ų34.68%0.07718%0.181CC..THydrogen-bonded Turntrans-76.27.6173.668.6162.7000113.6L34 D38 A41 L42 L45 L85 L86 R91 F126L34-I89 HydrophobicContact CD2-CD1 3.7Å; D38-I89 HydrophobicContact CB-CD1 4.07Å; A41-I89 HydrophobicContact CB-CG2 3.61Å; L42-I89 HydrophobicContact CD1-CD1 4.23Å; L42-I89 HydrophobicContact CD2-CD1 3.98Å; L42-I89 HydrophobicContact CD2-CG1 4.44Å; L42-I89 HydrophobicContact CD2-CG2 4.12Å; L42-I89 HydrophobicContact CG-CD1 4.02Å; L42-I89 HydrophobicContact CG-CG2 4.37Å; L45-I89 HydrophobicContact CD1-CG2 3.96Å; L85-I89 PolarHBondContact O-N 2.81Å; L85-I89 VanDerWaalsContact O-N 3.14Å; L86-I89 HydrophobicContact CD2-CD1 4.05Å; I89-R91 HydrophobicContact CD1-CB 4.05Å; I89-R91 HydrophobicContact CD1-CG 3.46Å; I89-R91 VanDerWaalsContact CD1-CG 3.46Å; I89-R91 HydrophobicContact CG1-CB 4.05Å; I89-R91 HydrophobicContact CG1-CG 3.75Å; I89-R91 PolarHBondContact O-N 3.33Å; I89-F126 HydrophobicContact CG2-CZ 4.29Å
90S84.8Confident83.6Confident73 Ų7339.8 Ų39.851%0.5121%0.209SC..THydrogen-bonded Turntrans58.325.3178.7-62.60000115.8L86 F87 H88 W92L86-S90 PolarHBondContact O-N 3.38Å; F87-S90 PolarHBondContact O-N 3.44Å; H88-S90 PolarHBondContact O-N 3.47Å; S90-W92 PolarHBondContact O-N 3.3Å; S90-W92 PolarHBondContact O-NE1 3.5Å
91R84.9Confident83.1Confident38 Ų3838 Ų3814%0.14320%0.197CC..  trans-84.262.2174.5-68.9-59.4-57-90.30.1111.6E33 L34 D38 L86 I89 D93 L94 L95E33-R91 PolarHBondContact O-NH1 3.22Å; E33-R91 PolarHBondContact O-NH2 3.39Å; L34-R91 HydrophobicContact CD2-CG 4.32Å; D38-R91 IonicContact OD1-NH1 3.23Å; D38-R91 IonicContact OD2-NH1 2.74Å; D38-R91 PolarHBondContact OD2-NH1 2.8Å; L86-R91 HydrophobicContact CD2-CB 4.23Å; L86-R91 PolarHBondContact O-N 3.1Å; I89-R91 HydrophobicContact CD1-CB 4.05Å; I89-R91 HydrophobicContact CD1-CG 3.46Å; I89-R91 VanDerWaalsContact CD1-CG 3.46Å; I89-R91 HydrophobicContact CG1-CB 4.05Å; I89-R91 HydrophobicContact CG1-CG 3.75Å; I89-R91 PolarHBondContact O-N 3.33Å; R91-D93 VanDerWaalsContact CA-OD1 3.27Å; R91-D93 WeakPolarHBondContact CA-OD1 3.5Å; R91-D93 IonicContact CZ-OD1 2.74Å; R91-D93 IonicContact CZ-OD2 3.5Å; R91-D93 IonicContact NE-OD1 3.43Å; R91-D93 PolarHBondContact NE-OD1 2.89Å; R91-D93 IonicContact NE-OD2 3.72Å; R91-D93 PolarHBondContact NE-OD2 3.5Å; R91-D93 IonicContact NH2-OD1 2.74Å; R91-D93 IonicContact NH2-OD2 3.42Å; R91-D93 PolarHBondContact NH2-OD2 3.43Å; R91-D93 PolarHBondContact O-N 3.1Å; R91-L94 HydrophobicContact CB-CB 4.44Å; R91-L94 HydrophobicContact CB-CD1 4.09Å; R91-L94 HydrophobicContact CB-CG 4.17Å; R91-L94 HydrophobicContact CG-CD1 4.46Å; R91-L94 PolarHBondContact O-N 2.82Å; R91-L94 VanDerWaalsContact O-N 3.1Å; R91-L95 PolarHBondContact O-N 2.8Å
92W80.5Confident82.5Confident71 Ų7141.2 Ų41.227%0.26921%0.214SC..Hα-helixtrans-61.1-31.2179.6-53.2103.3000113.1F87 S90 L94 L95 V96 R103F87-W92 HydrophobicContact CB-CH2 4.46Å; F87-W92 HydrophobicContact CD1-CH2 4.24Å; F87-W92 AromaticContact CD2-CH2 3.3Å; F87-W92 HydrophobicContact CD2-CH2 3.3Å; F87-W92 AromaticContact CD2-CZ3 3.3Å; F87-W92 HydrophobicContact CD2-CZ3 3.3Å; F87-W92 HydrophobicContact CE1-CH2 4.31Å; F87-W92 AromaticContact CE2-CH2 3.41Å; F87-W92 HydrophobicContact CE2-CH2 3.41Å; F87-W92 VanDerWaalsContact CE2-CH2 3.41Å; F87-W92 AromaticContact CE2-CZ3 3.63Å; F87-W92 HydrophobicContact CE2-CZ3 3.63Å; F87-W92 AromaticContact CG-CH2 3.74Å; F87-W92 HydrophobicContact CG-CH2 3.74Å; F87-W92 HydrophobicContact CG-CZ3 4.03Å; F87-W92 AromaticContact CZ-CH2 3.92Å; F87-W92 HydrophobicContact CZ-CH2 3.92Å; S90-W92 PolarHBondContact O-N 3.3Å; S90-W92 PolarHBondContact O-NE1 3.5Å; W92-L94 VanDerWaalsContact C-N 3.31Å; W92-L94 PolarHBondContact O-N 2.57Å; W92-L95 HydrophobicContact CE3-CD1 3.68Å; W92-L95 HydrophobicContact CZ3-CD1 3.88Å; W92-L95 PolarHBondContact O-N 3.37Å; W92-V96 WeakPolarHBondContact O-CG2 2.94Å; W92-V96 PolarHBondContact O-N 2.88Å; W92-R103 HydrophobicContact CE3-CB 4.27Å; W92-R103 HydrophobicContact CE3-CG 4.1Å; W92-R103 HydrophobicContact CH2-CG 4.12Å; W92-R103 HydrophobicContact CZ3-CB 4.16Å; W92-R103 HydrophobicContact CZ3-CG 3.68Å
93D80.8Confident81.8Confident63 Ų6348.9 Ų48.934%0.33724%0.243SC..Hα-helixtrans-55.8-45.2171.859.2-49.6000111.3R91 N97R91-D93 VanDerWaalsContact CA-OD1 3.27Å; R91-D93 WeakPolarHBondContact CA-OD1 3.5Å; R91-D93 IonicContact CZ-OD1 2.74Å; R91-D93 IonicContact CZ-OD2 3.5Å; R91-D93 IonicContact NE-OD1 3.43Å; R91-D93 PolarHBondContact NE-OD1 2.89Å; R91-D93 IonicContact NE-OD2 3.72Å; R91-D93 PolarHBondContact NE-OD2 3.5Å; R91-D93 IonicContact NH2-OD1 2.74Å; R91-D93 IonicContact NH2-OD2 3.42Å; R91-D93 PolarHBondContact NH2-OD2 3.43Å; R91-D93 PolarHBondContact O-N 3.1Å; D93-N97 WeakPolarHBondContact O-CB 3.45Å; D93-N97 PolarHBondContact O-N 3.34Å; D93-N97 PolarHBondContact O-ND2 3.23Å; D93-N97 VanDerWaalsContact O-ND2 3.1Å
94L85Confident81.3Confident1 Ų153.8 Ų53.81%0.00527%0.266CS..Hα-helixtrans-74.2-36.6-179.1-54.8-175.3000112.4I30 E33 L34 L86 R91 W92 F98I30-L94 HydrophobicContact CG2-CD1 4.21Å; E33-L94 HydrophobicContact CB-CD1 4.28Å; E33-L94 HydrophobicContact CB-CD2 3.57Å; E33-L94 HydrophobicContact CG-CD2 4.01Å; L34-L94 HydrophobicContact CD2-CD1 3.77Å; L34-L94 HydrophobicContact CG-CD1 3.91Å; L86-L94 HydrophobicContact CD1-CB 4.06Å; L86-L94 HydrophobicContact CD2-CB 4.41Å; L86-L94 HydrophobicContact CD2-CD1 4.02Å; R91-L94 HydrophobicContact CB-CB 4.44Å; R91-L94 HydrophobicContact CB-CD1 4.09Å; R91-L94 HydrophobicContact CB-CG 4.17Å; R91-L94 HydrophobicContact CG-CD1 4.46Å; R91-L94 PolarHBondContact O-N 2.82Å; R91-L94 VanDerWaalsContact O-N 3.1Å; W92-L94 VanDerWaalsContact C-N 3.31Å; W92-L94 PolarHBondContact O-N 2.57Å; L94-F98 HydrophobicContact CB-CD2 4.37Å; L94-F98 HydrophobicContact CD2-CD2 3.85Å; L94-F98 HydrophobicContact CD2-CE2 3.66Å; L94-F98 PolarHBondContact O-N 3.31Å; L94-F98 VanDerWaalsContact O-N 3.07Å
95L81.9Confident80.7Confident2 Ų256.7 Ų56.71%0.0128%0.28CS..Hα-helixtrans-60-44.7174.1-73.7173.8000112.6K83 L86 F87 R91 W92 L99 D100 C101K83-L95 HydrophobicContact CB-CD2 4.06Å; K83-L95 HydrophobicContact CG-CD2 4.19Å; L86-L95 HydrophobicContact CB-CD2 3.83Å; L86-L95 HydrophobicContact CB-CG 3.91Å; L86-L95 HydrophobicContact CD1-CD2 4.4Å; F87-L95 HydrophobicContact CB-CD1 4.09Å; R91-L95 PolarHBondContact O-N 2.8Å; W92-L95 HydrophobicContact CE3-CD1 3.68Å; W92-L95 HydrophobicContact CZ3-CD1 3.88Å; W92-L95 PolarHBondContact O-N 3.37Å; L95-L99 HydrophobicContact CD2-CD1 4.26Å; L95-L99 CarbonylContact O-C 3.49Å; L95-L99 PolarHBondContact O-N 3.2Å; L95-D100 PolarHBondContact O-N 3.25Å; L95-C101 HydrophobicContact CB-CB 4.47Å; L95-C101 HydrophobicContact CD2-CB 4.48Å; L95-C101 PolarHBondContact O-N 2.86Å; L95-C101 VanDerWaalsContact O-N 3.09Å
96V79.9Confident80.2Confident87 Ų8757 Ų5753%0.52728%0.281SS..Hα-helixtrans-78-44.5-178.5174.50000111.2W92W92-V96 WeakPolarHBondContact O-CG2 2.94Å; W92-V96 PolarHBondContact O-N 2.88Å
97N77.4Confident79.7Confident116 Ų11660.1 Ų60.162%0.6230%0.301SS*.Hα-helixtrans-77.9-30.3-172.1-65.3-23.6000114D93D93-N97 WeakPolarHBondContact O-CB 3.45Å; D93-N97 PolarHBondContact O-N 3.34Å; D93-N97 PolarHBondContact O-ND2 3.23Å; D93-N97 VanDerWaalsContact O-ND2 3.1Å
98F78.6Confident79Confident58 Ų5865.9 Ų65.925%0.25432%0.321SS..Hα-helixtrans-119.2-21.1-172.9-61.7-71.3000115M21 A29 I30 E33 L94M21-F98 HydrophobicContact CE-CD1 4.21Å; M21-F98 HydrophobicContact CE-CE1 4.2Å; M21-F98 HydrophobicContact SD-CD1 3.93Å; M21-F98 HydrophobicContact SD-CE1 4.27Å; A29-F98 HydrophobicContact CB-CD1 4.14Å; A29-F98 HydrophobicContact CB-CE1 3.56Å; A29-F98 HydrophobicContact CB-CZ 3.93Å; I30-F98 HydrophobicContact CD1-CB 3.82Å; I30-F98 HydrophobicContact CD1-CG 4.5Å; I30-F98 HydrophobicContact CG1-CB 3.68Å; I30-F98 HydrophobicContact CG1-CD2 3.86Å; I30-F98 HydrophobicContact CG1-CG 3.82Å; E33-F98 HydrophobicContact CG-CE2 4.37Å; L94-F98 HydrophobicContact CB-CD2 4.37Å; L94-F98 HydrophobicContact CD2-CD2 3.85Å; L94-F98 HydrophobicContact CD2-CE2 3.66Å; L94-F98 PolarHBondContact O-N 3.31Å; L94-F98 VanDerWaalsContact O-N 3.07Å
99L78.4Confident78.5Confident14 Ų1468.5 Ų68.57%0.07333%0.334CS..Hα-helixtrans-120.58-172.5-59.7178.7000114.3I30 L79 L82 K83 L86 L95 C101I30-L99 HydrophobicContact CD1-CD1 4.19Å; I30-L99 HydrophobicContact CD1-CD2 3.89Å; I30-L99 HydrophobicContact CD1-CG 3.97Å; L79-L99 HydrophobicContact CD1-CD2 3.86Å; L82-L99 HydrophobicContact CD2-CD1 4.09Å; L82-L99 HydrophobicContact CD2-CD2 4.4Å; L82-L99 HydrophobicContact CG-CD1 4.09Å; K83-L99 WeakPolarHBondContact CE-O 3.43Å; K83-L99 HydrophobicContact CG-CB 4.38Å; K83-L99 HydrophobicContact CG-CD1 3.9Å; K83-L99 PolarHBondContact NZ-O 3.17Å; L86-L99 HydrophobicContact CD1-CD1 3.63Å; L95-L99 HydrophobicContact CD2-CD1 4.26Å; L95-L99 CarbonylContact O-C 3.49Å; L95-L99 PolarHBondContact O-N 3.2Å; L99-C101 HydrophobicContact CB-CB 4.41Å; L99-C101 PolarHBondContact O-N 3.34Å; L99-C101 VanDerWaalsContact O-N 3.17Å
100D74.1Confident78Confident151 Ų15169.8 Ų69.881%0.80734%0.341SS*.  trans42.347.3-179.2-163.622.5000112.5L95L95-D100 PolarHBondContact O-N 3.25Å
101C74.4Confident77.1Confident4 Ų475.9 Ų75.93%0.02735%0.352CS..  trans-121.6120.7-167.5-161.70000111.3K83 L95 L99 M106K83-C101 HydrophobicContact CD-CB 4.25Å; L95-C101 HydrophobicContact CB-CB 4.47Å; L95-C101 HydrophobicContact CD2-CB 4.48Å; L95-C101 PolarHBondContact O-N 2.86Å; L95-C101 VanDerWaalsContact O-N 3.09Å; L99-C101 HydrophobicContact CB-CB 4.41Å; L99-C101 PolarHBondContact O-N 3.34Å; L99-C101 VanDerWaalsContact O-N 3.17Å; C101-M106 WeakPolarHBondContact SG-CG 3.38Å
102N74.4Confident76.3Confident68 Ų6877.6 Ų77.636%0.36436%0.364SS..  trans-91.3149.7178.968.183.2000111.6E104 E105 M106N102-E104 VanDerWaalsContact C-N 3.28Å; N102-E104 PolarHBondContact O-N 3.2Å; N102-E104 PolarHBondContact OD1-N 2.88Å; N102-E105 PolarHBondContact ND2-OE2 2.83Å; N102-E105 PolarHBondContact O-N 2.98Å; N102-E105 WeakPolarHBondContact OD1-CB 3.33Å; N102-E105 PolarHBondContact OD1-N 3.38Å; N102-M106 PolarHBondContact O-N 3.49Å
103R72.1Confident75.4Confident160 Ų16077.4 Ų77.460%0.60437%0.372SS*.Hα-helixtrans-61.6-34.6-176.1-175.6176.2-172.5-154.83.5113.3W92 V107W92-R103 HydrophobicContact CE3-CB 4.27Å; W92-R103 HydrophobicContact CE3-CG 4.1Å; W92-R103 HydrophobicContact CH2-CG 4.12Å; W92-R103 HydrophobicContact CZ3-CB 4.16Å; W92-R103 HydrophobicContact CZ3-CG 3.68Å; R103-V107 WeakPolarHBondContact O-CB 3.31Å; R103-V107 VanDerWaalsContact O-CG2 3.24Å; R103-V107 WeakPolarHBondContact O-CG2 3.41Å; R103-V107 PolarHBondContact O-N 2.77Å
104E74.7Confident74.5Confident149 Ų14981.5 Ų81.570%0.69639%0.394SS*.Hα-helixtrans-75.9-28.5-175.2-70.9148.1-160.800112.6N102 R108N102-E104 VanDerWaalsContact C-N 3.28Å; N102-E104 PolarHBondContact O-N 3.2Å; N102-E104 PolarHBondContact OD1-N 2.88Å; E104-R108 WeakPolarHBondContact O-CB 3.26Å; E104-R108 PolarHBondContact O-N 3.21Å
105E76.1Confident73.8Confident63 Ų6385.5 Ų85.529%0.29442%0.416SS..Hα-helixtrans-72.5-49.5170.4-177.1162.3-124.300111N102 V107 R108 E109N102-E105 PolarHBondContact ND2-OE2 2.83Å; N102-E105 PolarHBondContact O-N 2.98Å; N102-E105 WeakPolarHBondContact OD1-CB 3.33Å; N102-E105 PolarHBondContact OD1-N 3.38Å; E105-V107 VanDerWaalsContact C-N 3.33Å; E105-V107 PolarHBondContact O-N 2.76Å; E105-R108 CarbonylContact O-C 3.55Å; E105-R108 WeakPolarHBondContact O-CA 3.44Å; E105-R108 VanDerWaalsContact O-CB 3.3Å; E105-R108 WeakPolarHBondContact O-CB 3.36Å; E105-R108 PolarHBondContact O-N 2.78Å; E105-E109 HydrophobicContact CG-CG 4.49Å; E105-E109 WeakPolarHBondContact O-CG 3.28Å; E105-E109 PolarHBondContact O-N 2.77Å
106M79.2Confident73.6Confident5 Ų587.1 Ų87.13%0.02543%0.429CS..Hα-helixtrans-58.5-41.4174.2-72.3-62-59.400113K83 F87 C101 N102 R108 E109 L110K83-M106 HydrophobicContact CB-CE 3.87Å; K83-M106 HydrophobicContact CB-SD 3.76Å; K83-M106 HydrophobicContact CD-SD 4.31Å; F87-M106 HydrophobicContact CB-CE 4.09Å; F87-M106 HydrophobicContact CD2-CB 3.36Å; F87-M106 HydrophobicContact CD2-CE 4.2Å; F87-M106 HydrophobicContact CD2-CG 3.93Å; F87-M106 HydrophobicContact CE2-CB 3.44Å; F87-M106 VanDerWaalsContact CE2-CB 3.44Å; F87-M106 HydrophobicContact CE2-CG 4.47Å; F87-M106 HydrophobicContact CG-CB 4.45Å; F87-M106 HydrophobicContact CG-CE 4.31Å; C101-M106 WeakPolarHBondContact SG-CG 3.38Å; N102-M106 PolarHBondContact O-N 3.49Å; M106-R108 PolarHBondContact O-N 2.89Å; M106-E109 PolarHBondContact O-N 2.67Å; M106-L110 HydrophobicContact CE-CD1 3.79Å; M106-L110 HydrophobicContact CE-CG 4.14Å; M106-L110 VanDerWaalsContact O-CB 3.3Å; M106-L110 WeakPolarHBondContact O-CB 3.4Å; M106-L110 WeakPolarHBondContact O-CG 3.34Å; M106-L110 PolarHBondContact O-N 2.99Å
107V75.4Confident73.7Confident67 Ų6785.4 Ų85.441%0.40642%0.415SS..Hα-helixtrans-66.1-20.7174.5168.90000112.6F87 R103 E105F87-V107 HydrophobicContact CE2-CG2 3.88Å; F87-V107 HydrophobicContact CZ-CG2 3.78Å; R103-V107 WeakPolarHBondContact O-CB 3.31Å; R103-V107 VanDerWaalsContact O-CG2 3.24Å; R103-V107 WeakPolarHBondContact O-CG2 3.41Å; R103-V107 PolarHBondContact O-N 2.77Å; E105-V107 VanDerWaalsContact C-N 3.33Å; E105-V107 PolarHBondContact O-N 2.76Å
108R74.3Confident74.1Confident152 Ų15280 Ų8057%0.57439%0.386SS*.Hα-helixtrans-87.6-41.7176.2-168.1-169.9-50.5124.49111.5E104 E105 M106 R111E104-R108 WeakPolarHBondContact O-CB 3.26Å; E104-R108 PolarHBondContact O-N 3.21Å; E105-R108 CarbonylContact O-C 3.55Å; E105-R108 WeakPolarHBondContact O-CA 3.44Å; E105-R108 VanDerWaalsContact O-CB 3.3Å; E105-R108 WeakPolarHBondContact O-CB 3.36Å; E105-R108 PolarHBondContact O-N 2.78Å; M106-R108 PolarHBondContact O-N 2.89Å; R108-R111 WeakPolarHBondContact O-CB 3.48Å; R108-R111 PolarHBondContact O-N 3.46Å
109E75Confident74.5Confident82 Ų8278.5 Ų78.538%0.38338%0.383SS..Hα-helixtrans-65.7-51.9176.6-70179.7166.300110.8E105 M106 R111 D112 N115E105-E109 HydrophobicContact CG-CG 4.49Å; E105-E109 WeakPolarHBondContact O-CG 3.28Å; E105-E109 PolarHBondContact O-N 2.77Å; M106-E109 PolarHBondContact O-N 2.67Å; E109-R111 PolarHBondContact O-N 2.81Å; E109-R111 VanDerWaalsContact O-N 3.13Å; E109-D112 PolarHBondContact O-N 2.88Å; E109-N115 WeakPolarHBondContact O-CB 3.44Å; E109-N115 PolarHBondContact O-ND2 3.18Å
110L75.3Confident74.8Confident42 Ų4280 Ų8022%0.2239%0.394CS..THydrogen-bonded Turntrans-74.35.7177.3-59.2176.8000114.1E84 F87 M106 D112 A116E84-L110 HydrophobicContact CB-CD2 4.48Å; E84-L110 HydrophobicContact CG-CD1 4.24Å; E84-L110 HydrophobicContact CG-CD2 3.87Å; F87-L110 HydrophobicContact CD1-CD1 3.77Å; F87-L110 HydrophobicContact CD2-CD1 4.39Å; F87-L110 HydrophobicContact CE1-CD1 3.85Å; F87-L110 HydrophobicContact CE2-CD1 4.45Å; F87-L110 HydrophobicContact CG-CD1 4.08Å; F87-L110 HydrophobicContact CZ-CD1 4.21Å; M106-L110 HydrophobicContact CE-CD1 3.79Å; M106-L110 HydrophobicContact CE-CG 4.14Å; M106-L110 VanDerWaalsContact O-CB 3.3Å; M106-L110 WeakPolarHBondContact O-CB 3.4Å; M106-L110 WeakPolarHBondContact O-CG 3.34Å; M106-L110 PolarHBondContact O-N 2.99Å; L110-D112 VanDerWaalsContact C-N 3.33Å; L110-A116 HydrophobicContact CD2-CB 4.07Å
111R67.6Low75.4Confident200 Ų20073.3 Ų73.376%0.75536%0.357SS*.THydrogen-bonded Turntrans-75.5-29167.8-174178-67.6-149.7-2.7111.1R108 E109R108-R111 WeakPolarHBondContact O-CB 3.48Å; R108-R111 PolarHBondContact O-N 3.46Å; E109-R111 PolarHBondContact O-N 2.81Å; E109-R111 VanDerWaalsContact O-N 3.13Å
112D67.6Low76.2Confident75 Ų7573.9 Ų73.940%0.40136%0.359SS..SBendtrans-86.8120174.9-161.3-35.3000109.3E109 L110 D114 N115E109-D112 PolarHBondContact O-N 2.88Å; L110-D112 VanDerWaalsContact C-N 3.33Å; D112-D114 PolarHBondContact O-N 3.45Å; D112-D114 PolarHBondContact OD1-N 3.29Å; D112-D114 VanDerWaalsContact OD1-N 3.11Å; D112-N115 HydrophobicContact CB-CB 4.42Å; D112-N115 WeakPolarHBondContact CB-ND2 3.44Å; D112-N115 PolarHBondContact O-N 3.03Å
113P61Low76.8Confident67 Ų6771.3 Ų71.344%0.43535%0.346SS..G310 helixtrans-58.4-27177.7-23.934.9000113.8N115 A116P113-N115 VanDerWaalsContact C-N 3.28Å; P113-N115 PolarHBondContact O-N 2.61Å; P113-A116 PolarHBondContact O-N 2.96Å
114D62.8Low77.7Confident149 Ų14964.2 Ų64.280%0.79732%0.32SS*.G310 helixtrans-77.2-14.2-177.4-68.2-15.9000112.7D112D112-D114 PolarHBondContact O-N 3.45Å; D112-D114 PolarHBondContact OD1-N 3.29Å; D112-D114 VanDerWaalsContact OD1-N 3.11Å
115N68.9Low78.4Confident85 Ų8557.1 Ų57.146%0.45529%0.287SS..G310 helixtrans-92.4-18.1175.4-68.9-30.6000113.4E109 D112 P113E109-N115 WeakPolarHBondContact O-CB 3.44Å; E109-N115 PolarHBondContact O-ND2 3.18Å; D112-N115 HydrophobicContact CB-CB 4.42Å; D112-N115 WeakPolarHBondContact CB-ND2 3.44Å; D112-N115 PolarHBondContact O-N 3.03Å; P113-N115 VanDerWaalsContact C-N 3.28Å; P113-N115 PolarHBondContact O-N 2.61Å
116A77.9Confident79.1Confident36 Ų3654.5 Ų54.530%0.29827%0.274SS..  trans-83122.5179.900000110.3L110 P113L110-A116 HydrophobicContact CD2-CB 4.07Å; P113-A116 PolarHBondContact O-N 2.96Å
117Q82.6Confident79.5Confident50 Ų5059.3 Ų59.323%0.23430%0.295CS..  trans-96.6-24.4-179.8-73.5158.179.900111.9Y49 S80 F81 E84Y49-Q117 PolarHBondContact OH-O 3.23Å; S80-Q117 PolarHBondContact OG-NE2 3.2Å; F81-Q117 HydrophobicContact CD2-CB 3.69Å; F81-Q117 HydrophobicContact CE2-CB 4.16Å; E84-Q117 PolarHBondContact OE1-N 3.44Å; E84-Q117 WeakPolarHBondContact OE2-CA 3.41Å; E84-Q117 WeakPolarHBondContact OE2-CB 3.46Å; E84-Q117 PolarHBondContact OE2-N 3.38Å
118I86Confident80.1Confident3 Ų356.2 Ų56.22%0.01528%0.276CS..SBendtrans-82.5132.2176.2-56.2178.5000108.9L45 F81 E84 L85 R122 V123L45-I118 HydrophobicContact CB-CD1 4.35Å; L45-I118 HydrophobicContact CB-CG2 4.41Å; L45-I118 HydrophobicContact CD2-CG2 4.21Å; F81-I118 HydrophobicContact CD2-CG1 4.37Å; F81-I118 HydrophobicContact CE2-CG1 3.74Å; F81-I118 HydrophobicContact CZ-CG1 4.38Å; E84-I118 HydrophobicContact CB-CD1 4.4Å; E84-I118 HydrophobicContact CG-CD1 3.89Å; E84-I118 HydrophobicContact CG-CG1 4.04Å; E84-I118 WeakPolarHBondContact OE1-CB 3.46Å; E84-I118 PolarHBondContact OE1-N 2.96Å; E84-I118 PolarHBondContact OE2-N 3.47Å; L85-I118 HydrophobicContact CB-CD1 4.49Å; L85-I118 HydrophobicContact CD2-CD1 3.58Å; L85-I118 HydrophobicContact CG-CD1 3.87Å; I118-R122 HydrophobicContact CG2-CB 4.07Å; I118-V123 HydrophobicContact CB-CG2 4.24Å; I118-V123 HydrophobicContact CG2-CG2 3.8Å
119S86.3Confident80.8Confident26 Ų2649.8 Ų49.818%0.18225%0.254CS..  trans-60133.6-17770.20000110.8D48 Y121 R122 V123D48-S119 WeakPolarHBondContact OD2-CB 3.4Å; D48-S119 PolarHBondContact OD2-OG 3.21Å; S119-Y121 PolarHBondContact O-N 3.38Å; S119-R122 PolarHBondContact O-N 2.92Å; S119-R122 WeakPolarHBondContact OG-CG 3.41Å; S119-R122 PolarHBondContact OG-N 3.44Å; S119-V123 PolarHBondContact O-N 3.17Å
120P84.6Confident81.4Confident47 Ų4752.1 Ų52.131%0.30527%0.265SS..Hα-helixtrans-55.9-28.1-179.9-29.136.6000113.3M124 Y198 R205P120-M124 WeakPolarHBondContact O-CB 3.44Å; P120-M124 PolarHBondContact O-N 3Å; P120-Y198 HydrophobicContact CB-CE2 3.93Å; P120-R205 VanDerWaalsContact CG-NH1 3.28Å
121Y87.4Confident81.9Confident10 Ų1055 Ų554%0.03928%0.277CS..Hα-helixtrans-62.2-49.5171.8167.8-106.3000112.9S119 V123 M124 L125 E167 A173 E174 L177S119-Y121 PolarHBondContact O-N 3.38Å; Y121-V123 VanDerWaalsContact C-N 3.33Å; Y121-V123 PolarHBondContact O-N 2.85Å; Y121-M124 HydrophobicContact CD2-CE 4.01Å; Y121-M124 HydrophobicContact CE2-CE 4.41Å; Y121-M124 WeakPolarHBondContact O-CB 3.33Å; Y121-M124 PolarHBondContact O-N 3.06Å; Y121-L125 HydrophobicContact CD2-CD1 4.44Å; Y121-L125 HydrophobicContact CE1-CD1 3.89Å; Y121-L125 HydrophobicContact CE2-CD1 3.77Å; Y121-L125 HydrophobicContact CE2-CG 4.17Å; Y121-L125 VanDerWaalsContact CZ-CD1 3.46Å; Y121-L125 PolarHBondContact O-N 2.82Å; Y121-L125 WeakPolarHBondContact OH-CD1 3.44Å; Y121-E167 VanDerWaalsContact CE1-OE1 3.27Å; Y121-E167 WeakPolarHBondContact CE1-OE1 3.4Å; Y121-E167 PolarHBondContact OH-OE1 3.48Å; Y121-A173 VanDerWaalsContact CE2-C 3.41Å; Y121-A173 WeakPolarHBondContact OH-CA 3.43Å; Y121-E174 HydrophobicContact CD1-CB 4.42Å; Y121-E174 HydrophobicContact CD2-CB 4Å; Y121-E174 HydrophobicContact CE2-CB 4.49Å; Y121-E174 HydrophobicContact CG-CB 3.95Å; Y121-L177 HydrophobicContact CD2-CD2 4.36Å; Y121-L177 HydrophobicContact CE2-CD2 3.91Å
122R90.8Very high82.7Confident15 Ų1546.4 Ų46.46%0.05725%0.248CC..Hα-helixtrans-61.2-42.5175.9-70.6-75.1172.2-147.7-9111.7L45 D48 I118 S119 M124 L125 F126 E167L45-R122 HydrophobicContact CD2-CB 4.37Å; D48-R122 IonicContact OD1-CZ 3.28Å; D48-R122 VanDerWaalsContact OD1-CZ 3.28Å; D48-R122 IonicContact OD1-NE 2.76Å; D48-R122 PolarHBondContact OD1-NE 3.48Å; D48-R122 IonicContact OD1-NH2 2.79Å; D48-R122 PolarHBondContact OD1-NH2 2.97Å; D48-R122 WeakPolarHBondContact OD2-CG 3.45Å; D48-R122 IonicContact OD2-NE 2.95Å; I118-R122 HydrophobicContact CG2-CB 4.07Å; S119-R122 PolarHBondContact O-N 2.92Å; S119-R122 WeakPolarHBondContact OG-CG 3.41Å; S119-R122 PolarHBondContact OG-N 3.44Å; R122-M124 VanDerWaalsContact C-N 3.32Å; R122-M124 PolarHBondContact O-N 3.29Å; R122-L125 PolarHBondContact O-N 2.82Å; R122-F126 WeakPolarHBondContact O-CB 3.16Å; R122-F126 PolarHBondContact O-N 2.97Å; R122-E167 IonicContact CZ-OE1 2.65Å; R122-E167 IonicContact CZ-OE2 2.66Å; R122-E167 IonicContact NH1-OE1 2.64Å; R122-E167 PolarHBondContact NH1-OE1 3.14Å; R122-E167 IonicContact NH1-OE2 3.79Å; R122-E167 PolarHBondContact NH1-OE2 3.43Å; R122-E167 IonicContact NH2-OE1 3.76Å; R122-E167 PolarHBondContact NH2-OE1 2.79Å; R122-E167 IonicContact NH2-OE2 2.83Å; R122-E167 PolarHBondContact NH2-OE2 2.58Å
123V87.4Confident83.6Confident14 Ų1445.5 Ų45.59%0.08525%0.247CC..Hα-helixtrans-62.9-38.9176.4175.80000111.5H88 I118 S119 Y121 K127H88-V123 VanDerWaalsContact CE1-CG1 3.42Å; H88-V123 WeakPolarHBondContact CE1-CG1 3.27Å; I118-V123 HydrophobicContact CB-CG2 4.24Å; I118-V123 HydrophobicContact CG2-CG2 3.8Å; S119-V123 PolarHBondContact O-N 3.17Å; Y121-V123 VanDerWaalsContact C-N 3.33Å; Y121-V123 PolarHBondContact O-N 2.85Å; V123-K127 HydrophobicContact CG1-CD 4.07Å; V123-K127 WeakPolarHBondContact O-CB 3.32Å; V123-K127 VanDerWaalsContact O-CG 3.26Å; V123-K127 WeakPolarHBondContact O-CG 3.28Å; V123-K127 PolarHBondContact O-N 3.46Å
124M90.8Very high84.5Confident12 Ų1248.4 Ų48.46%0.05926%0.255CS..Hα-helixtrans-64.1-51.2175.7177.3-81.6-66.700111.1P120 Y121 R122 F126 K127 L128 L177 I195 Y198P120-M124 WeakPolarHBondContact O-CB 3.44Å; P120-M124 PolarHBondContact O-N 3Å; Y121-M124 HydrophobicContact CD2-CE 4.01Å; Y121-M124 HydrophobicContact CE2-CE 4.41Å; Y121-M124 WeakPolarHBondContact O-CB 3.33Å; Y121-M124 PolarHBondContact O-N 3.06Å; R122-M124 VanDerWaalsContact C-N 3.32Å; R122-M124 PolarHBondContact O-N 3.29Å; M124-F126 PolarHBondContact O-N 3.42Å; M124-K127 PolarHBondContact O-N 3.24Å; M124-K127 VanDerWaalsContact O-N 3.17Å; M124-L128 WeakPolarHBondContact O-CG 3.38Å; M124-L128 PolarHBondContact O-N 3.5Å; M124-L128 VanDerWaalsContact O-N 3.08Å; M124-L128 HydrophobicContact SD-CD1 3.54Å; M124-L128 VanDerWaalsContact SD-CD1 3.54Å; M124-L128 HydrophobicContact SD-CG 4.13Å; M124-L177 HydrophobicContact CE-CD1 4.05Å; M124-L177 HydrophobicContact CE-CD2 3.88Å; M124-I195 HydrophobicContact SD-CG1 4.2Å; M124-Y198 HydrophobicContact CB-CD2 3.89Å; M124-Y198 HydrophobicContact CB-CG 4.19Å; M124-Y198 HydrophobicContact CE-CD1 4.25Å; M124-Y198 HydrophobicContact CE-CG 4.46Å; M124-Y198 HydrophobicContact CG-CD2 4.15Å; M124-Y198 HydrophobicContact CG-CG 3.92Å
125L90.1Very high85.4Confident0 Ų047.2 Ų47.20%025%0.247CC..Hα-helixtrans-61.3-42.1178.9-68.9-177.2000112.6F44 Y121 R122 K127 L128 S129 F163 L172 L180F44-L125 HydrophobicContact CE1-CB 3.86Å; F44-L125 HydrophobicContact CZ-CB 3.65Å; F44-L125 HydrophobicContact CZ-CD1 3.91Å; F44-L125 HydrophobicContact CZ-CG 4.46Å; Y121-L125 HydrophobicContact CD2-CD1 4.44Å; Y121-L125 HydrophobicContact CE1-CD1 3.89Å; Y121-L125 HydrophobicContact CE2-CD1 3.77Å; Y121-L125 HydrophobicContact CE2-CG 4.17Å; Y121-L125 VanDerWaalsContact CZ-CD1 3.46Å; Y121-L125 PolarHBondContact O-N 2.82Å; Y121-L125 WeakPolarHBondContact OH-CD1 3.44Å; R122-L125 PolarHBondContact O-N 2.82Å; L125-K127 PolarHBondContact O-N 3.4Å; L125-L128 HydrophobicContact CD2-CD1 4.39Å; L125-L128 WeakPolarHBondContact O-CB 3.5Å; L125-L128 PolarHBondContact O-N 2.63Å; L125-L128 VanDerWaalsContact O-N 3.09Å; L125-S129 PolarHBondContact O-N 2.91Å; L125-S129 VanDerWaalsContact O-N 3.1Å; L125-F163 HydrophobicContact CB-CD2 3.96Å; L125-F163 HydrophobicContact CB-CE2 4.15Å; L125-F163 HydrophobicContact CD1-CB 4.45Å; L125-F163 HydrophobicContact CD2-CD2 4.22Å; L125-F163 HydrophobicContact CD2-CE2 4.21Å; L125-F163 HydrophobicContact CD2-CG 4.41Å; L125-F163 HydrophobicContact CD2-CZ 4.4Å; L125-F163 HydrophobicContact CG-CD2 4.47Å; L125-F163 WeakPolarHBondContact O-CE2 3.49Å; L125-L172 HydrophobicContact CD1-CD2 3.93Å; L125-L172 HydrophobicContact CD2-CD2 4.02Å; L125-L180 HydrophobicContact CD2-CD2 3.51Å
126F90.7Very high86.1Confident8 Ų845 Ų454%0.03523%0.234CC..Hα-helixtrans-61.3-43.5174.8179.8-103.6000111.9A41 F44 L45 H88 I89 R122 M124 L128 S129 E130 L160A41-F126 HydrophobicContact CB-CD2 4.19Å; A41-F126 HydrophobicContact CB-CE2 3.4Å; A41-F126 VanDerWaalsContact CB-CE2 3.4Å; A41-F126 HydrophobicContact CB-CZ 3.95Å; F44-F126 HydrophobicContact CD1-CB 4.34Å; F44-F126 HydrophobicContact CE1-CB 4.35Å; L45-F126 HydrophobicContact CD2-CB 3.84Å; L45-F126 HydrophobicContact CD2-CG 4.17Å; H88-F126 VanDerWaalsContact O-CE1 3.32Å; H88-F126 WeakPolarHBondContact O-CE1 3.42Å; I89-F126 HydrophobicContact CG2-CZ 4.29Å; R122-F126 WeakPolarHBondContact O-CB 3.16Å; R122-F126 PolarHBondContact O-N 2.97Å; M124-F126 PolarHBondContact O-N 3.42Å; F126-L128 PolarHBondContact O-N 3.28Å; F126-L128 VanDerWaalsContact O-N 3.17Å; F126-S129 PolarHBondContact O-N 3.5Å; F126-S129 VanDerWaalsContact O-N 3.09Å; F126-S129 PolarHBondContact O-OG 3.23Å; F126-E130 HydrophobicContact CD1-CG 4.37Å; F126-E130 HydrophobicContact CE1-CG 3.79Å; F126-E130 HydrophobicContact CE2-CG 4.1Å; F126-E130 HydrophobicContact CZ-CG 3.63Å; F126-E130 WeakPolarHBondContact O-CG 3.42Å; F126-E130 PolarHBondContact O-N 2.73Å; F126-L160 HydrophobicContact CD2-CD1 4.07Å; F126-L160 HydrophobicContact CD2-CD2 4.2Å; F126-L160 HydrophobicContact CE2-CD1 4.3Å
127K87.7Confident86.5Confident106 Ų10644.7 Ų44.746%0.46123%0.228SC..Hα-helixtrans-66.6-14174.7-74.5173.9-179.61760114.6V123 M124 L125 K194V123-K127 HydrophobicContact CG1-CD 4.07Å; V123-K127 WeakPolarHBondContact O-CB 3.32Å; V123-K127 VanDerWaalsContact O-CG 3.26Å; V123-K127 WeakPolarHBondContact O-CG 3.28Å; V123-K127 PolarHBondContact O-N 3.46Å; M124-K127 PolarHBondContact O-N 3.24Å; M124-K127 VanDerWaalsContact O-N 3.17Å; L125-K127 PolarHBondContact O-N 3.4Å; K127-K194 PolarHBondContact O-NZ 3.19Å
128L87.8Confident86.5Confident2 Ų249 Ų491%0.0124%0.242CC..Hα-helixtrans-84.8-37.8169.8-67.1179.1000111.2M124 L125 F126 E130 E131 V132 F163 L180 L191 K194 I195M124-L128 WeakPolarHBondContact O-CG 3.38Å; M124-L128 PolarHBondContact O-N 3.5Å; M124-L128 VanDerWaalsContact O-N 3.08Å; M124-L128 HydrophobicContact SD-CD1 3.54Å; M124-L128 VanDerWaalsContact SD-CD1 3.54Å; M124-L128 HydrophobicContact SD-CG 4.13Å; L125-L128 HydrophobicContact CD2-CD1 4.39Å; L125-L128 WeakPolarHBondContact O-CB 3.5Å; L125-L128 PolarHBondContact O-N 2.63Å; L125-L128 VanDerWaalsContact O-N 3.09Å; F126-L128 PolarHBondContact O-N 3.28Å; F126-L128 VanDerWaalsContact O-N 3.17Å; L128-E130 VanDerWaalsContact C-N 3.34Å; L128-E130 PolarHBondContact O-N 2.66Å; L128-E131 PolarHBondContact O-N 3.43Å; L128-V132 WeakPolarHBondContact O-CG2 3.31Å; L128-V132 PolarHBondContact O-N 3.36Å; L128-F163 HydrophobicContact CB-CE2 4.35Å; L128-F163 HydrophobicContact CB-CZ 4.21Å; L128-L180 HydrophobicContact CD1-CD2 3.9Å; L128-L191 HydrophobicContact CD2-CB 3.95Å; L128-L191 HydrophobicContact CD2-CD2 3.92Å; L128-L191 HydrophobicContact CD2-CG 4.49Å; L128-K194 HydrophobicContact CD2-CB 4.08Å; L128-K194 HydrophobicContact CD2-CD 3.98Å; L128-I195 HydrophobicContact CD1-CD1 4.03Å; L128-I195 HydrophobicContact CD1-CG1 3.91Å
129S88.8Confident86.3Confident17 Ų1751.5 Ų51.512%0.11926%0.26CS..Hα-helixtrans-65.4-36.6177.962.20000113L125 F126 E131 V132 L160L125-S129 PolarHBondContact O-N 2.91Å; L125-S129 VanDerWaalsContact O-N 3.1Å; F126-S129 PolarHBondContact O-N 3.5Å; F126-S129 VanDerWaalsContact O-N 3.09Å; F126-S129 PolarHBondContact O-OG 3.23Å; S129-E131 VanDerWaalsContact C-N 3.25Å; S129-E131 PolarHBondContact O-N 2.98Å; S129-V132 PolarHBondContact O-N 2.92Å; S129-L160 WeakPolarHBondContact OG-CD2 3.34Å
130E87.6Confident86.2Confident131 Ų13150.3 Ų50.361%0.61225%0.251SS*.THydrogen-bonded Turntrans-68.9-18.9179.5-63.6-58.497.600114.3F126 L128F126-E130 HydrophobicContact CD1-CG 4.37Å; F126-E130 HydrophobicContact CE1-CG 3.79Å; F126-E130 HydrophobicContact CE2-CG 4.1Å; F126-E130 HydrophobicContact CZ-CG 3.63Å; F126-E130 WeakPolarHBondContact O-CG 3.42Å; F126-E130 PolarHBondContact O-N 2.73Å; L128-E130 VanDerWaalsContact C-N 3.34Å; L128-E130 PolarHBondContact O-N 2.66Å
131E84.6Confident86.1Confident101 Ų10148.9 Ų48.947%0.47224%0.24SC..THydrogen-bonded Turntrans-108.2-1.4-178.6-79.9-179.3-157.900114.1L128 S129 L191 K194L128-E131 PolarHBondContact O-N 3.43Å; S129-E131 VanDerWaalsContact C-N 3.25Å; S129-E131 PolarHBondContact O-N 2.98Å; E131-L191 HydrophobicContact CB-CD2 4.08Å; E131-K194 IonicContact OE1-NZ 3.28Å; E131-K194 PolarHBondContact OE1-NZ 3.13Å; E131-K194 VanDerWaalsContact OE2-CE 3.25Å; E131-K194 WeakPolarHBondContact OE2-CE 3.07Å; E131-K194 IonicContact OE2-NZ 2.97Å; E131-K194 PolarHBondContact OE2-NZ 2.99Å
132V86.3Confident85.9Confident21 Ų2155.5 Ų55.513%0.12727%0.269CS..  trans-89.4115.8175.4164.30000109.6L128 S129 E136 L137 F140 L159 L191L128-V132 WeakPolarHBondContact O-CG2 3.31Å; L128-V132 PolarHBondContact O-N 3.36Å; S129-V132 PolarHBondContact O-N 2.92Å; V132-E136 HydrophobicContact CG1-CB 3.87Å; V132-L137 HydrophobicContact CG1-CB 3.98Å; V132-F140 HydrophobicContact CG1-CD2 4.38Å; V132-F140 HydrophobicContact CG1-CE2 4.49Å; V132-F140 HydrophobicContact CG2-CE2 3.97Å; V132-F140 HydrophobicContact CG2-CZ 4.49Å; V132-L159 HydrophobicContact CB-CD2 3.68Å; V132-L159 HydrophobicContact CG1-CD2 3.8Å; V132-L159 HydrophobicContact CG2-CD2 3.6Å; V132-L191 HydrophobicContact CG2-CD1 3.41Å; V132-L191 VanDerWaalsContact CG2-CD1 3.41Å; V132-L191 HydrophobicContact CG2-CD2 4.31Å
133S85.1Confident85.4Confident55 Ų5556.8 Ų56.839%0.38528%0.277SS..  trans-68.9162.4173.569.30000112.3L135 E136 L137S133-L135 PolarHBondContact O-N 2.85Å; S133-L135 VanDerWaalsContact O-N 3.16Å; S133-E136 WeakPolarHBondContact CB-OE2 3.32Å; S133-E136 PolarHBondContact N-OE2 2.88Å; S133-E136 PolarHBondContact O-N 2.91Å; S133-E136 WeakPolarHBondContact OG-CG 3.44Å; S133-E136 PolarHBondContact OG-N 2.79Å; S133-E136 PolarHBondContact OG-OE2 2.76Å; S133-L137 PolarHBondContact O-N 3.37Å
134E81.5Confident85Confident129 Ų12956.1 Ų56.160%0.60327%0.273SS*.Hα-helixtrans-57.2-32.6177.7-158.5-158.2153.100113.1R138E134-R138 VanDerWaalsContact O-CG 3.31Å; E134-R138 WeakPolarHBondContact O-CG 3.39Å; E134-R138 PolarHBondContact O-N 3.3Å; E134-R138 VanDerWaalsContact O-N 3.12Å; E134-R138 IonicContact OE1-CZ 3.93Å; E134-R138 IonicContact OE1-NE 3.28Å; E134-R138 PolarHBondContact OE1-NE 3.36Å; E134-R138 IonicContact OE1-NH2 2.75Å; E134-R138 PolarHBondContact OE1-NH2 2.87Å
135L80.1Confident84.3Confident123 Ų12357.6 Ų57.664%0.64428%0.281SS*.Hα-helixtrans-71-40.7176.2-68.4175000111.8S133 R138 S139S133-L135 PolarHBondContact O-N 2.85Å; S133-L135 VanDerWaalsContact O-N 3.16Å; L135-R138 PolarHBondContact O-N 3.41Å; L135-S139 PolarHBondContact O-N 2.9Å; L135-S139 PolarHBondContact O-OG 3.19Å
136E85.1Confident83.1Confident38 Ų3865 Ų6518%0.17832%0.321CS..Hα-helixtrans-68.1-39.5174.9-71161.7127.600110.8V132 S133 R138 S139 F140 V187 N188V132-E136 HydrophobicContact CG1-CB 3.87Å; S133-E136 WeakPolarHBondContact CB-OE2 3.32Å; S133-E136 PolarHBondContact N-OE2 2.88Å; S133-E136 PolarHBondContact O-N 2.91Å; S133-E136 WeakPolarHBondContact OG-CG 3.44Å; S133-E136 PolarHBondContact OG-N 2.79Å; S133-E136 PolarHBondContact OG-OE2 2.76Å; E136-R138 VanDerWaalsContact C-N 3.3Å; E136-R138 PolarHBondContact O-N 3.11Å; E136-S139 CarbonylContact O-C 3.45Å; E136-S139 WeakPolarHBondContact O-CA 3.14Å; E136-S139 VanDerWaalsContact O-CB 3.31Å; E136-S139 WeakPolarHBondContact O-CB 3.31Å; E136-S139 PolarHBondContact O-N 2.94Å; E136-F140 WeakPolarHBondContact O-CD2 3.4Å; E136-F140 PolarHBondContact O-N 3.42Å; E136-V187 HydrophobicContact CB-CG1 3.51Å; E136-V187 HydrophobicContact CG-CG1 3.68Å; E136-N188 VanDerWaalsContact OE1-CB 3.24Å; E136-N188 WeakPolarHBondContact OE1-CB 3.36Å; E136-N188 PolarHBondContact OE1-ND2 3.16Å
137L84.8Confident82Confident30 Ų3068.7 Ų68.716%0.15734%0.338CS..Hα-helixtrans-58.3-40.3173.6-179.655.3000112.2V132 S133 S139 F140 K141 L159 I162V132-L137 HydrophobicContact CG1-CB 3.98Å; S133-L137 PolarHBondContact O-N 3.37Å; L137-S139 VanDerWaalsContact C-N 3.33Å; L137-F140 WeakPolarHBondContact O-CB 3.19Å; L137-F140 PolarHBondContact O-N 2.9Å; L137-K141 WeakPolarHBondContact O-CG 3.14Å; L137-K141 PolarHBondContact O-N 2.67Å; L137-L159 HydrophobicContact CD1-CB 3.87Å; L137-L159 HydrophobicContact CD1-CD1 3.99Å; L137-L159 HydrophobicContact CD1-CG 4.44Å; L137-I162 HydrophobicContact CD1-CD1 3.61Å
138R82.4Confident81.3Confident142 Ų14263.7 Ų63.754%0.53632%0.316SS..Hα-helixtrans-64.5-36.8172.8-69.3169.6-171-169.23.7111.9E134 L135 E136 K141 F142E134-R138 VanDerWaalsContact O-CG 3.31Å; E134-R138 WeakPolarHBondContact O-CG 3.39Å; E134-R138 PolarHBondContact O-N 3.3Å; E134-R138 VanDerWaalsContact O-N 3.12Å; E134-R138 IonicContact OE1-CZ 3.93Å; E134-R138 IonicContact OE1-NE 3.28Å; E134-R138 PolarHBondContact OE1-NE 3.36Å; E134-R138 IonicContact OE1-NH2 2.75Å; E134-R138 PolarHBondContact OE1-NH2 2.87Å; L135-R138 PolarHBondContact O-N 3.41Å; E136-R138 VanDerWaalsContact C-N 3.3Å; E136-R138 PolarHBondContact O-N 3.11Å; R138-K141 PolarHBondContact O-N 2.95Å; R138-F142 WeakPolarHBondContact O-CB 3.4Å; R138-F142 PolarHBondContact O-N 3.07Å
139S82.9Confident80.2Confident55 Ų5566.9 Ų66.939%0.38534%0.337SS..Hα-helixtrans-67.2-40172.7-60.10000112.5L135 E136 L137 F142 L143L135-S139 PolarHBondContact O-N 2.9Å; L135-S139 PolarHBondContact O-OG 3.19Å; E136-S139 CarbonylContact O-C 3.45Å; E136-S139 WeakPolarHBondContact O-CA 3.14Å; E136-S139 VanDerWaalsContact O-CB 3.31Å; E136-S139 WeakPolarHBondContact O-CB 3.31Å; E136-S139 PolarHBondContact O-N 2.94Å; L137-S139 VanDerWaalsContact C-N 3.33Å; S139-F142 PolarHBondContact O-N 3.34Å; S139-L143 WeakPolarHBondContact O-CG 3.1Å; S139-L143 PolarHBondContact O-N 3.48Å
140F83.9Confident78.7Confident1 Ų173.5 Ų73.50%0.00436%0.364CS..Hα-helixtrans-56.5-53.1170.4-95.1-97.7000111.1V132 E136 L137 F142 L143 L144 L159 F163 L180 I183 V187 L191V132-F140 HydrophobicContact CG1-CD2 4.38Å; V132-F140 HydrophobicContact CG1-CE2 4.49Å; V132-F140 HydrophobicContact CG2-CE2 3.97Å; V132-F140 HydrophobicContact CG2-CZ 4.49Å; E136-F140 WeakPolarHBondContact O-CD2 3.4Å; E136-F140 PolarHBondContact O-N 3.42Å; L137-F140 WeakPolarHBondContact O-CB 3.19Å; L137-F140 PolarHBondContact O-N 2.9Å; F140-F142 VanDerWaalsContact C-N 3.27Å; F140-F142 PolarHBondContact O-N 2.92Å; F140-L143 PolarHBondContact O-N 2.95Å; F140-L144 WeakPolarHBondContact O-CB 3.5Å; F140-L144 WeakPolarHBondContact O-CG 3.27Å; F140-L144 PolarHBondContact O-N 3.42Å; F140-L159 HydrophobicContact CB-CD1 4.44Å; F140-L159 HydrophobicContact CD1-CD1 3.78Å; F140-L159 HydrophobicContact CE1-CD1 4.18Å; F140-L159 HydrophobicContact CG-CD1 4.11Å; F140-F163 HydrophobicContact CE1-CE1 4.38Å; F140-L180 HydrophobicContact CE1-CD1 3.78Å; F140-L180 HydrophobicContact CZ-CD1 4.34Å; F140-I183 HydrophobicContact CD1-CG2 3.4Å; F140-I183 VanDerWaalsContact CD1-CG2 3.4Å; F140-I183 HydrophobicContact CD2-CG2 4.24Å; F140-I183 HydrophobicContact CE1-CB 4.31Å; F140-I183 HydrophobicContact CE1-CG2 3.47Å; F140-I183 VanDerWaalsContact CE1-CG2 3.47Å; F140-I183 HydrophobicContact CE2-CG2 4.29Å; F140-I183 HydrophobicContact CG-CG2 3.81Å; F140-I183 HydrophobicContact CZ-CG2 3.93Å; F140-V187 HydrophobicContact CD2-CB 4.2Å; F140-V187 HydrophobicContact CD2-CG1 3.91Å; F140-V187 HydrophobicContact CD2-CG2 4.01Å; F140-V187 HydrophobicContact CE2-CB 4.03Å; F140-V187 HydrophobicContact CE2-CG1 3.91Å; F140-V187 HydrophobicContact CE2-CG2 4.25Å; F140-L191 HydrophobicContact CE2-CD1 4.22Å; F140-L191 HydrophobicContact CZ-CD1 4.42Å
141K83.5Confident77.1Confident16 Ų1671.9 Ų71.97%0.0737%0.366CS..Hα-helixtrans-58.4-39175.1-68.8-178.1-174.6-1700111.5L137 R138 N145 L153 E154 D155 L157 I162L137-K141 WeakPolarHBondContact O-CG 3.14Å; L137-K141 PolarHBondContact O-N 2.67Å; R138-K141 PolarHBondContact O-N 2.95Å; K141-N145 PolarHBondContact O-N 2.66Å; K141-N145 PolarHBondContact O-ND2 3.39Å; K141-L153 WeakPolarHBondContact O-CD1 3.49Å; K141-E154 PolarHBondContact NZ-O 2.95Å; K141-D155 PolarHBondContact NZ-O 2.7Å; K141-L157 WeakPolarHBondContact CE-O 3.36Å; K141-L157 PolarHBondContact NZ-O 3.1Å; K141-I162 HydrophobicContact CD-CD1 4.39Å; K141-I162 HydrophobicContact CG-CD1 3.67Å
142F81.7Confident75.9Confident149 Ų14971.6 Ų71.665%0.65436%0.363SS*.Hα-helixtrans-63.8-50.1178.7-178.3-96.9000112.6R138 S139 F140 N145R138-F142 WeakPolarHBondContact O-CB 3.4Å; R138-F142 PolarHBondContact O-N 3.07Å; S139-F142 PolarHBondContact O-N 3.34Å; F140-F142 VanDerWaalsContact C-N 3.27Å; F140-F142 PolarHBondContact O-N 2.92Å; F142-N145 WeakPolarHBondContact CA-ND2 3.27Å; F142-N145 WeakPolarHBondContact O-CB 3.43Å; F142-N145 PolarHBondContact O-N 3.37Å; F142-N145 PolarHBondContact O-ND2 3.03Å
143L80.1Confident74.9Confident42 Ų4271.3 Ų71.322%0.2236%0.361CS..Hα-helixtrans-65.4-39.2-179.3-68.6170.3000111.7S139 F140 N145 I183 Q186 V187S139-L143 WeakPolarHBondContact O-CG 3.1Å; S139-L143 PolarHBondContact O-N 3.48Å; F140-L143 PolarHBondContact O-N 2.95Å; L143-N145 PolarHBondContact O-N 3Å; L143-I183 HydrophobicContact CB-CG1 4.5Å; L143-I183 HydrophobicContact CD1-CG2 4.05Å; L143-Q186 HydrophobicContact CD1-CB 3.86Å; L143-V187 HydrophobicContact CD1-CG2 3.64Å
144L80.3Confident73.9Confident0 Ų074.2 Ų74.20%037%0.368CS..Hα-helixtrans-69.2-13.6177.2-73.9167.8000114.3F140 N146 E147 I148 L153 I162 M166 I183F140-L144 WeakPolarHBondContact O-CB 3.5Å; F140-L144 WeakPolarHBondContact O-CG 3.27Å; F140-L144 PolarHBondContact O-N 3.42Å; L144-N146 PolarHBondContact O-N 3.42Å; L144-N146 VanDerWaalsContact O-N 3.08Å; L144-E147 PolarHBondContact O-N 3.27Å; L144-I148 HydrophobicContact CB-CD1 4.35Å; L144-I148 HydrophobicContact CB-CG1 4.48Å; L144-I148 HydrophobicContact CD1-CD1 4.38Å; L144-I148 HydrophobicContact CD2-CD1 4.09Å; L144-I148 HydrophobicContact CD2-CG1 4.45Å; L144-I148 PolarHBondContact O-N 3.41Å; L144-L153 HydrophobicContact CB-CD1 3.96Å; L144-I162 HydrophobicContact CD1-CG2 3.36Å; L144-M166 HydrophobicContact CD1-SD 4.02Å; L144-M166 HydrophobicContact CD2-CE 4.15Å; L144-M166 HydrophobicContact CD2-CG 4.31Å; L144-M166 HydrophobicContact CD2-SD 4.14Å; L144-I183 HydrophobicContact CD1-CD1 4.45Å; L144-I183 HydrophobicContact CD2-CD1 3.52Å; L144-I183 HydrophobicContact CG-CD1 3.82Å
145N74.7Confident73Confident44 Ų4475.6 Ų75.624%0.23538%0.38CS..THydrogen-bonded Turntrans-60.1-21.4180-80.5-50.5000114.7K141 F142 L143 E147 K150K141-N145 PolarHBondContact O-N 2.66Å; K141-N145 PolarHBondContact O-ND2 3.39Å; F142-N145 WeakPolarHBondContact CA-ND2 3.27Å; F142-N145 WeakPolarHBondContact O-CB 3.43Å; F142-N145 PolarHBondContact O-N 3.37Å; F142-N145 PolarHBondContact O-ND2 3.03Å; L143-N145 PolarHBondContact O-N 3Å; N145-E147 VanDerWaalsContact C-N 3.33Å; N145-K150 WeakPolarHBondContact OD1-CG 3.32Å
146N65.7Low72.3Confident155 Ų15575.9 Ų75.983%0.82938%0.382SS*.THydrogen-bonded Turntrans-78.8-19.8176.8-65.1-29.1000112.3L144L144-N146 PolarHBondContact O-N 3.42Å; L144-N146 VanDerWaalsContact O-N 3.08Å
147E67.1Low72Confident86 Ų8676 Ų7640%0.40238%0.383SS..THydrogen-bonded Turntrans-117-26.5-171.4-60.8-177.2144.900112.3L144 N145 R169 M171 T179L144-E147 PolarHBondContact O-N 3.27Å; N145-E147 VanDerWaalsContact C-N 3.33Å; E147-R169 PolarHBondContact O-NH1 2.78Å; E147-M171 HydrophobicContact CB-CE 3.63Å; E147-M171 HydrophobicContact CB-SD 4.15Å; E147-M171 HydrophobicContact CG-CE 3.88Å; E147-M171 WeakPolarHBondContact OE2-CE 3.39Å; E147-T179 WeakPolarHBondContact OE2-CG2 3.38Å
148I72.6Confident72Confident1 Ų176.5 Ų76.51%0.00539%0.39CS..SBendtrans-122.9116.3179-54-173.7000108.1L144 K150 K152 L153 E165 M166L144-I148 HydrophobicContact CB-CD1 4.35Å; L144-I148 HydrophobicContact CB-CG1 4.48Å; L144-I148 HydrophobicContact CD1-CD1 4.38Å; L144-I148 HydrophobicContact CD2-CD1 4.09Å; L144-I148 HydrophobicContact CD2-CG1 4.45Å; L144-I148 PolarHBondContact O-N 3.41Å; I148-K150 PolarHBondContact O-N 3.29Å; I148-K152 HydrophobicContact CG2-CB 4.11Å; I148-L153 HydrophobicContact CB-CD1 3.95Å; I148-L153 HydrophobicContact CB-CD2 4.37Å; I148-L153 HydrophobicContact CB-CG 4.09Å; I148-L153 HydrophobicContact CD1-CD2 4.4Å; I148-L153 HydrophobicContact CG2-CD1 4.12Å; I148-L153 HydrophobicContact CG2-CD2 3.99Å; I148-L153 HydrophobicContact CG2-CG 3.7Å; I148-E165 HydrophobicContact CD1-CG 4.33Å; I148-E165 HydrophobicContact CG2-CG 4.35Å; I148-M166 HydrophobicContact CD1-CG 4.08Å
149P65.6Low72.2Confident68 Ų6870.1 Ų70.144%0.44237%0.366SS..  trans-54.1136175.7-28.835.7000112.6C151 K152 R169P149-C151 PolarHBondContact O-N 3.2Å; P149-K152 PolarHBondContact O-N 3.01Å; P149-R169 VanDerWaalsContact CD-NH1 3.32Å
150K58.4Low72.4Confident156 Ų15668.4 Ų68.468%0.67835%0.353SS*.G310 helixtrans-47-32.1-178.1-73.5179178-171.30115.2N145 I148 K152 L153N145-K150 WeakPolarHBondContact OD1-CG 3.32Å; I148-K150 PolarHBondContact O-N 3.29Å; K150-K152 PolarHBondContact O-N 3.14Å; K150-K152 VanDerWaalsContact O-N 3.08Å; K150-L153 PolarHBondContact O-N 3.45Å; K150-L153 VanDerWaalsContact O-N 3.17Å
151C53.3Low72.5Confident97 Ų9773 Ų7366%0.65537%0.374SS*.G310 helixtrans-69.33.4175.860.10000115.1P149P149-C151 PolarHBondContact O-N 3.2Å
152K59.1Low72.6Confident96 Ų9672.3 Ų72.342%0.41737%0.371SS..G310 helixtrans-130.511.9174-64.5-177.4123.2-148.10112.5I148 P149 K150 L157 E165 R169I148-K152 HydrophobicContact CG2-CB 4.11Å; P149-K152 PolarHBondContact O-N 3.01Å; K150-K152 PolarHBondContact O-N 3.14Å; K150-K152 VanDerWaalsContact O-N 3.08Å; K152-L157 VanDerWaalsContact O-CD1 3.29Å; K152-L157 WeakPolarHBondContact O-CD1 3.48Å; K152-E165 WeakPolarHBondContact CD-OE1 3.25Å; K152-E165 IonicContact NZ-OE1 3.79Å; K152-E165 PolarHBondContact NZ-OE1 2.81Å; K152-E165 IonicContact NZ-OE2 2.86Å; K152-E165 PolarHBondContact NZ-OE2 2.93Å; K152-R169 VanDerWaalsContact CD-NH2 3.33Å
153L65.1Low72.9Confident14 Ų1465.2 Ų65.27%0.07334%0.34CS..SBendtrans-121.955.4171.4-68.3175.6000107.9K141 L144 I148 K150 I162K141-L153 WeakPolarHBondContact O-CD1 3.49Å; L144-L153 HydrophobicContact CB-CD1 3.96Å; I148-L153 HydrophobicContact CB-CD1 3.95Å; I148-L153 HydrophobicContact CB-CD2 4.37Å; I148-L153 HydrophobicContact CB-CG 4.09Å; I148-L153 HydrophobicContact CD1-CD2 4.4Å; I148-L153 HydrophobicContact CG2-CD1 4.12Å; I148-L153 HydrophobicContact CG2-CD2 3.99Å; I148-L153 HydrophobicContact CG2-CG 3.7Å; K150-L153 PolarHBondContact O-N 3.45Å; K150-L153 VanDerWaalsContact O-N 3.17Å; L153-I162 HydrophobicContact CD2-CG1 4.4Å
154E63.8Low73.2Confident117 Ų11763.8 Ų63.855%0.54733%0.333SS..  trans-62.8148.1177.8-60.2-172.5-162.200110.1K141 D156 L157K141-E154 PolarHBondContact NZ-O 2.95Å; E154-D156 VanDerWaalsContact CB-OD1 3.27Å; E154-D156 WeakPolarHBondContact CB-OD1 3.48Å; E154-D156 PolarHBondContact O-N 2.98Å; E154-D156 VanDerWaalsContact O-N 3.17Å; E154-L157 HydrophobicContact CB-CD1 4.44Å; E154-L157 HydrophobicContact CB-CG 4.29Å; E154-L157 PolarHBondContact O-N 3.46Å
155D62.2Low73.3Confident158 Ų15864.9 Ų64.985%0.84534%0.338SS*.THydrogen-bonded Turntrans-64.5-23.8-167.5-77.6-41.2000113.1K141K141-D155 PolarHBondContact NZ-O 2.7Å
156D66.3Low73.7Confident128 Ų12862.8 Ų62.868%0.68433%0.327SS*.THydrogen-bonded Turntrans-83-18.8178.962.3-23.5000114.9E154 S158E154-D156 VanDerWaalsContact CB-OD1 3.27Å; E154-D156 WeakPolarHBondContact CB-OD1 3.48Å; E154-D156 PolarHBondContact O-N 2.98Å; E154-D156 VanDerWaalsContact O-N 3.17Å; D156-S158 PolarHBondContact O-N 3.48Å
157L78.3Confident74.8Confident40 Ų4057.5 Ų57.521%0.20930%0.297CS..  trans-58.9131.6-178.1-67.9176.2000113.1K141 K152 E154 E161K141-L157 WeakPolarHBondContact CE-O 3.36Å; K141-L157 PolarHBondContact NZ-O 3.1Å; K152-L157 VanDerWaalsContact O-CD1 3.29Å; K152-L157 WeakPolarHBondContact O-CD1 3.48Å; E154-L157 HydrophobicContact CB-CD1 4.44Å; E154-L157 HydrophobicContact CB-CG 4.29Å; E154-L157 PolarHBondContact O-N 3.46Å; L157-E161 HydrophobicContact CD2-CB 4.22Å
158S84.9Confident75.5Confident42 Ų4258.6 Ų58.629%0.29430%0.301SS..  trans-73.4160.817366.70000112.3D156 L160 E161 I162D156-S158 PolarHBondContact O-N 3.48Å; S158-L160 PolarHBondContact O-N 3.35Å; S158-E161 WeakPolarHBondContact CB-OE2 3.41Å; S158-E161 PolarHBondContact N-OE2 3.18Å; S158-E161 PolarHBondContact O-N 3Å; S158-E161 VanDerWaalsContact OG-CD 3.32Å; S158-E161 WeakPolarHBondContact OG-CG 3.43Å; S158-E161 PolarHBondContact OG-N 3.18Å; S158-E161 PolarHBondContact OG-OE2 3.22Å; S158-I162 WeakPolarHBondContact O-CG1 3.42Å; S158-I162 PolarHBondContact O-N 3.1Å; S158-I162 VanDerWaalsContact O-N 3.09Å
159L86.4Confident75.8Confident8 Ų861.8 Ų61.84%0.04231%0.313CS..Hα-helixtrans-64.1-30.8176.8-170.654.9000112.5V132 L137 F140 I162 F163V132-L159 HydrophobicContact CB-CD2 3.68Å; V132-L159 HydrophobicContact CG1-CD2 3.8Å; V132-L159 HydrophobicContact CG2-CD2 3.6Å; L137-L159 HydrophobicContact CD1-CB 3.87Å; L137-L159 HydrophobicContact CD1-CD1 3.99Å; L137-L159 HydrophobicContact CD1-CG 4.44Å; F140-L159 HydrophobicContact CB-CD1 4.44Å; F140-L159 HydrophobicContact CD1-CD1 3.78Å; F140-L159 HydrophobicContact CE1-CD1 4.18Å; F140-L159 HydrophobicContact CG-CD1 4.11Å; L159-I162 HydrophobicContact CD1-CB 4.24Å; L159-I162 HydrophobicContact CD1-CD1 4.24Å; L159-I162 HydrophobicContact CD1-CG2 4.35Å; L159-I162 WeakPolarHBondContact O-CB 3.28Å; L159-I162 PolarHBondContact O-N 2.95Å; L159-F163 HydrophobicContact CD1-CD1 4.29Å; L159-F163 HydrophobicContact CD1-CE1 3.77Å; L159-F163 HydrophobicContact CD1-CZ 3.94Å; L159-F163 HydrophobicContact CD2-CE1 4.32Å; L159-F163 HydrophobicContact CD2-CE2 4.09Å; L159-F163 HydrophobicContact CD2-CZ 3.66Å; L159-F163 HydrophobicContact CG-CD1 4.48Å; L159-F163 HydrophobicContact CG-CD2 4.35Å; L159-F163 HydrophobicContact CG-CE1 3.91Å; L159-F163 HydrophobicContact CG-CE2 3.78Å; L159-F163 HydrophobicContact CG-CZ 3.54Å; L159-F163 WeakPolarHBondContact O-CD2 3.39Å; L159-F163 WeakPolarHBondContact O-CG 3.31Å; L159-F163 PolarHBondContact O-N 3.09Å
160L88.4Confident76.5Confident19 Ų1964.1 Ų64.110%0.09933%0.326CS..Hα-helixtrans-62.9-42174.3-65.2-179.1000111.8F44 F126 S129 S158 I162 F163 V164F44-L160 HydrophobicContact CB-CB 4.49Å; F44-L160 HydrophobicContact CB-CD1 4.03Å; F44-L160 HydrophobicContact CB-CD2 4.41Å; F44-L160 HydrophobicContact CD1-CD2 3.72Å; F44-L160 HydrophobicContact CD2-CB 3.9Å; F44-L160 HydrophobicContact CD2-CD2 3.87Å; F44-L160 HydrophobicContact CD2-CG 4.37Å; F44-L160 HydrophobicContact CE1-CD2 3.87Å; F44-L160 HydrophobicContact CE2-CB 4.41Å; F44-L160 HydrophobicContact CE2-CD2 4.01Å; F44-L160 HydrophobicContact CG-CB 4.24Å; F44-L160 HydrophobicContact CG-CD1 4.25Å; F44-L160 HydrophobicContact CG-CD2 3.72Å; F44-L160 HydrophobicContact CG-CG 4.29Å; F44-L160 HydrophobicContact CZ-CD2 4.01Å; F126-L160 HydrophobicContact CD2-CD1 4.07Å; F126-L160 HydrophobicContact CD2-CD2 4.2Å; F126-L160 HydrophobicContact CE2-CD1 4.3Å; S129-L160 WeakPolarHBondContact OG-CD2 3.34Å; S158-L160 PolarHBondContact O-N 3.35Å; L160-I162 VanDerWaalsContact C-N 3.35Å; L160-F163 HydrophobicContact CD2-CD2 4.39Å; L160-F163 PolarHBondContact O-N 3.1Å; L160-V164 WeakPolarHBondContact O-CG2 3.38Å; L160-V164 PolarHBondContact O-N 3.04Å
161E85.3Confident77.5Confident97 Ų9758.3 Ų58.345%0.45330%0.302SS..Hα-helixtrans-68.8-34.1175.9-70.2163.512600112.3L157 S158 V164 E165L157-E161 HydrophobicContact CD2-CB 4.22Å; S158-E161 WeakPolarHBondContact CB-OE2 3.41Å; S158-E161 PolarHBondContact N-OE2 3.18Å; S158-E161 PolarHBondContact O-N 3Å; S158-E161 VanDerWaalsContact OG-CD 3.32Å; S158-E161 WeakPolarHBondContact OG-CG 3.43Å; S158-E161 PolarHBondContact OG-N 3.18Å; S158-E161 PolarHBondContact OG-OE2 3.22Å; E161-V164 PolarHBondContact O-N 2.83Å; E161-E165 PolarHBondContact O-N 2.99Å
162I85.1Confident79.2Confident1 Ų153.9 Ų53.91%0.00527%0.271CS..Hα-helixtrans-63-48.5171.4-65.9172.2000110.5L137 K141 L144 L153 S158 L159 L160 V164 E165 M166L137-I162 HydrophobicContact CD1-CD1 3.61Å; K141-I162 HydrophobicContact CD-CD1 4.39Å; K141-I162 HydrophobicContact CG-CD1 3.67Å; L144-I162 HydrophobicContact CD1-CG2 3.36Å; L153-I162 HydrophobicContact CD2-CG1 4.4Å; S158-I162 WeakPolarHBondContact O-CG1 3.42Å; S158-I162 PolarHBondContact O-N 3.1Å; S158-I162 VanDerWaalsContact O-N 3.09Å; L159-I162 HydrophobicContact CD1-CB 4.24Å; L159-I162 HydrophobicContact CD1-CD1 4.24Å; L159-I162 HydrophobicContact CD1-CG2 4.35Å; L159-I162 WeakPolarHBondContact O-CB 3.28Å; L159-I162 PolarHBondContact O-N 2.95Å; L160-I162 VanDerWaalsContact C-N 3.35Å; I162-V164 VanDerWaalsContact C-N 3.27Å; I162-V164 PolarHBondContact O-N 3.37Å; I162-E165 CarbonylContact O-C 3.54Å; I162-E165 PolarHBondContact O-N 2.86Å; I162-M166 HydrophobicContact CG2-CG 4.35Å; I162-M166 HydrophobicContact CG2-SD 4.04Å; I162-M166 WeakPolarHBondContact O-CG 3.45Å; I162-M166 PolarHBondContact O-N 3.39Å
163F89.4Confident80.4Confident0 Ų050.8 Ų50.80%026%0.264CS..Hα-helixtrans-58-40.7176.1-66.4-28000111.9F44 L125 L128 F140 L159 L160 E165 M166 E167 L172 L180F44-F163 HydrophobicContact CE2-CB 4.16Å; F44-F163 HydrophobicContact CZ-CB 4.45Å; F44-F163 HydrophobicContact CZ-CD2 4.37Å; L125-F163 HydrophobicContact CB-CD2 3.96Å; L125-F163 HydrophobicContact CB-CE2 4.15Å; L125-F163 HydrophobicContact CD1-CB 4.45Å; L125-F163 HydrophobicContact CD2-CD2 4.22Å; L125-F163 HydrophobicContact CD2-CE2 4.21Å; L125-F163 HydrophobicContact CD2-CG 4.41Å; L125-F163 HydrophobicContact CD2-CZ 4.4Å; L125-F163 HydrophobicContact CG-CD2 4.47Å; L125-F163 WeakPolarHBondContact O-CE2 3.49Å; L128-F163 HydrophobicContact CB-CE2 4.35Å; L128-F163 HydrophobicContact CB-CZ 4.21Å; F140-F163 HydrophobicContact CE1-CE1 4.38Å; L159-F163 HydrophobicContact CD1-CD1 4.29Å; L159-F163 HydrophobicContact CD1-CE1 3.77Å; L159-F163 HydrophobicContact CD1-CZ 3.94Å; L159-F163 HydrophobicContact CD2-CE1 4.32Å; L159-F163 HydrophobicContact CD2-CE2 4.09Å; L159-F163 HydrophobicContact CD2-CZ 3.66Å; L159-F163 HydrophobicContact CG-CD1 4.48Å; L159-F163 HydrophobicContact CG-CD2 4.35Å; L159-F163 HydrophobicContact CG-CE1 3.91Å; L159-F163 HydrophobicContact CG-CE2 3.78Å; L159-F163 HydrophobicContact CG-CZ 3.54Å; L159-F163 WeakPolarHBondContact O-CD2 3.39Å; L159-F163 WeakPolarHBondContact O-CG 3.31Å; L159-F163 PolarHBondContact O-N 3.09Å; L160-F163 HydrophobicContact CD2-CD2 4.39Å; L160-F163 PolarHBondContact O-N 3.1Å; F163-E165 PolarHBondContact O-N 3.48Å; F163-M166 HydrophobicContact CD1-SD 4.15Å; F163-M166 PolarHBondContact O-N 3.16Å; F163-E167 WeakPolarHBondContact O-CG 2.97Å; F163-E167 PolarHBondContact O-N 3.02Å; F163-L172 HydrophobicContact CB-CD2 3.89Å; F163-L172 HydrophobicContact CD1-CD2 3.83Å; F163-L172 HydrophobicContact CG-CD2 4.07Å; F163-L180 HydrophobicContact CE1-CD1 3.62Å; F163-L180 HydrophobicContact CE1-CD2 4.36Å; F163-L180 HydrophobicContact CZ-CD1 4.25Å
164V85.6Confident81.3Confident13 Ų1355.4 Ų55.48%0.07929%0.285CS..Hα-helixtrans-62.9-38.7173.4166.80000112.6F44 L47 H52 L160 E161 I162 K168F44-V164 HydrophobicContact CD2-CG2 3.91Å; F44-V164 HydrophobicContact CE2-CG2 3.98Å; L47-V164 HydrophobicContact CD1-CG2 3.46Å; L47-V164 VanDerWaalsContact CD1-CG2 3.46Å; H52-V164 VanDerWaalsContact CD2-CG1 3.45Å; H52-V164 WeakPolarHBondContact CD2-CG1 3.39Å; L160-V164 WeakPolarHBondContact O-CG2 3.38Å; L160-V164 PolarHBondContact O-N 3.04Å; E161-V164 PolarHBondContact O-N 2.83Å; I162-V164 VanDerWaalsContact C-N 3.27Å; I162-V164 PolarHBondContact O-N 3.37Å; V164-K168 HydrophobicContact CG1-CD 4.21Å; V164-K168 VanDerWaalsContact CG1-CE 3.45Å; V164-K168 WeakPolarHBondContact O-CB 3.47Å; V164-K168 WeakPolarHBondContact O-CD 3.24Å; V164-K168 WeakPolarHBondContact O-CG 3.37Å; V164-K168 PolarHBondContact O-N 3.43Å
165E82.6Confident81.9Confident22 Ų2256.7 Ų56.710%0.10330%0.296CS..Hα-helixtrans-72.6-31.7175.4-177.765-166.100112.3I148 K152 E161 I162 F163 K168 R169I148-E165 HydrophobicContact CD1-CG 4.33Å; I148-E165 HydrophobicContact CG2-CG 4.35Å; K152-E165 WeakPolarHBondContact CD-OE1 3.25Å; K152-E165 IonicContact NZ-OE1 3.79Å; K152-E165 PolarHBondContact NZ-OE1 2.81Å; K152-E165 IonicContact NZ-OE2 2.86Å; K152-E165 PolarHBondContact NZ-OE2 2.93Å; E161-E165 PolarHBondContact O-N 2.99Å; I162-E165 CarbonylContact O-C 3.54Å; I162-E165 PolarHBondContact O-N 2.86Å; F163-E165 PolarHBondContact O-N 3.48Å; E165-K168 PolarHBondContact O-N 3.32Å; E165-K168 WeakPolarHBondContact OE2-CD 3.31Å; E165-R169 WeakPolarHBondContact O-CD 3.37Å; E165-R169 VanDerWaalsContact O-CG 3.24Å; E165-R169 WeakPolarHBondContact O-CG 3.47Å; E165-R169 PolarHBondContact O-N 2.66Å; E165-R169 IonicContact OE1-CZ 3.24Å; E165-R169 IonicContact OE1-NE 3.98Å; E165-R169 PolarHBondContact OE1-NE 3.31Å; E165-R169 IonicContact OE1-NH2 2.73Å; E165-R169 PolarHBondContact OE1-NH2 3.21Å
166M83.8Confident82.8Confident0 Ų051.9 Ų51.90%027%0.27CS..Hα-helixtrans-65.5-43169.7-66.4172.872.500111.5L144 I148 I162 F163 R169 T170 M171 L172 T179 I183L144-M166 HydrophobicContact CD1-SD 4.02Å; L144-M166 HydrophobicContact CD2-CE 4.15Å; L144-M166 HydrophobicContact CD2-CG 4.31Å; L144-M166 HydrophobicContact CD2-SD 4.14Å; I148-M166 HydrophobicContact CD1-CG 4.08Å; I162-M166 HydrophobicContact CG2-CG 4.35Å; I162-M166 HydrophobicContact CG2-SD 4.04Å; I162-M166 WeakPolarHBondContact O-CG 3.45Å; I162-M166 PolarHBondContact O-N 3.39Å; F163-M166 HydrophobicContact CD1-SD 4.15Å; F163-M166 PolarHBondContact O-N 3.16Å; M166-R169 CarbonylContact O-C 3.55Å; M166-R169 PolarHBondContact O-N 3.41Å; M166-R169 VanDerWaalsContact O-N 3.13Å; M166-T170 PolarHBondContact O-N 3.32Å; M166-M171 HydrophobicContact CB-CB 4.4Å; M166-M171 PolarHBondContact O-N 3.19Å; M166-L172 HydrophobicContact CB-CB 3.74Å; M166-L172 HydrophobicContact CB-CD2 4.28Å; M166-L172 HydrophobicContact CE-CB 4.44Å; M166-L172 HydrophobicContact SD-CD2 4.5Å; M166-T179 HydrophobicContact CE-CG2 3.89Å; M166-I183 HydrophobicContact CE-CD1 4.16Å
167E87.6Confident83.8Confident44 Ų4445.9 Ų45.921%0.20624%0.238CC..Hα-helixtrans-61.8-45.5173-77.4-179.2-172.600112Y121 R122 F163 R169 T170 L172Y121-E167 VanDerWaalsContact CE1-OE1 3.27Å; Y121-E167 WeakPolarHBondContact CE1-OE1 3.4Å; Y121-E167 PolarHBondContact OH-OE1 3.48Å; R122-E167 IonicContact CZ-OE1 2.65Å; R122-E167 IonicContact CZ-OE2 2.66Å; R122-E167 IonicContact NH1-OE1 2.64Å; R122-E167 PolarHBondContact NH1-OE1 3.14Å; R122-E167 IonicContact NH1-OE2 3.79Å; R122-E167 PolarHBondContact NH1-OE2 3.43Å; R122-E167 IonicContact NH2-OE1 3.76Å; R122-E167 PolarHBondContact NH2-OE1 2.79Å; R122-E167 IonicContact NH2-OE2 2.83Å; R122-E167 PolarHBondContact NH2-OE2 2.58Å; F163-E167 WeakPolarHBondContact O-CG 2.97Å; F163-E167 PolarHBondContact O-N 3.02Å; E167-R169 PolarHBondContact O-N 3.44Å; E167-T170 PolarHBondContact O-N 3.35Å; E167-L172 HydrophobicContact CG-CB 4.28Å
168K82.6Confident84.1Confident110 Ų11049.3 Ų49.348%0.47825%0.253SS..Hα-helixtrans-57-23.4174.5-75.2164.6-172.9159.60112.8H52 V164 E165H52-K168 PolarHBondContact CE1-NZ 3.45Å; H52-K168 PolarHBondContact NE2-NZ 3.48Å; V164-K168 HydrophobicContact CG1-CD 4.21Å; V164-K168 VanDerWaalsContact CG1-CE 3.45Å; V164-K168 WeakPolarHBondContact O-CB 3.47Å; V164-K168 WeakPolarHBondContact O-CD 3.24Å; V164-K168 WeakPolarHBondContact O-CG 3.37Å; V164-K168 PolarHBondContact O-N 3.43Å; E165-K168 PolarHBondContact O-N 3.32Å; E165-K168 WeakPolarHBondContact OE2-CD 3.31Å
169R77.3Confident84Confident67 Ų6748.7 Ų48.725%0.25325%0.247SC..THydrogen-bonded Turntrans-99.93.9178.2-67.7167.4-179.5-98.4-10.3113.9E147 P149 K152 E165 M166 E167 M171E147-R169 PolarHBondContact O-NH1 2.78Å; P149-R169 VanDerWaalsContact CD-NH1 3.32Å; K152-R169 VanDerWaalsContact CD-NH2 3.33Å; E165-R169 WeakPolarHBondContact O-CD 3.37Å; E165-R169 VanDerWaalsContact O-CG 3.24Å; E165-R169 WeakPolarHBondContact O-CG 3.47Å; E165-R169 PolarHBondContact O-N 2.66Å; E165-R169 IonicContact OE1-CZ 3.24Å; E165-R169 IonicContact OE1-NE 3.98Å; E165-R169 PolarHBondContact OE1-NE 3.31Å; E165-R169 IonicContact OE1-NH2 2.73Å; E165-R169 PolarHBondContact OE1-NH2 3.21Å; M166-R169 CarbonylContact O-C 3.55Å; M166-R169 PolarHBondContact O-N 3.41Å; M166-R169 VanDerWaalsContact O-N 3.13Å; E167-R169 PolarHBondContact O-N 3.44Å; R169-M171 HydrophobicContact CB-CG 3.7Å; R169-M171 HydrophobicContact CB-SD 3.97Å; R169-M171 WeakPolarHBondContact O-CG 3.48Å; R169-M171 PolarHBondContact O-N 2.76Å
170T80.9Confident84.1Confident118 Ų11848.3 Ų48.372%0.72425%0.245SC*.THydrogen-bonded Turntrans6021-175.560.50000114.8M166 E167 N176M166-T170 PolarHBondContact O-N 3.32Å; E167-T170 PolarHBondContact O-N 3.35Å; T170-N176 PolarHBondContact O-ND2 2.87Å
171M80.7Confident83.9Confident34 Ų3448.9 Ų48.917%0.16725%0.247CC..SBendtrans-90.3-12.5180-56.1-170.665.600112.9E147 M166 R169 T179E147-M171 HydrophobicContact CB-CE 3.63Å; E147-M171 HydrophobicContact CB-SD 4.15Å; E147-M171 HydrophobicContact CG-CE 3.88Å; E147-M171 WeakPolarHBondContact OE2-CE 3.39Å; M166-M171 HydrophobicContact CB-CB 4.4Å; M166-M171 PolarHBondContact O-N 3.19Å; R169-M171 HydrophobicContact CB-CG 3.7Å; R169-M171 HydrophobicContact CB-SD 3.97Å; R169-M171 WeakPolarHBondContact O-CG 3.48Å; R169-M171 PolarHBondContact O-N 2.76Å; M171-T179 HydrophobicContact CE-CG2 4.03Å
172L87.4Confident83.9Confident4 Ų447.5 Ų47.52%0.02125%0.248CC..  trans-139.1130.3177.9-171.560.9000108.5L125 F163 M166 E167 L177 L180L125-L172 HydrophobicContact CD1-CD2 3.93Å; L125-L172 HydrophobicContact CD2-CD2 4.02Å; F163-L172 HydrophobicContact CB-CD2 3.89Å; F163-L172 HydrophobicContact CD1-CD2 3.83Å; F163-L172 HydrophobicContact CG-CD2 4.07Å; M166-L172 HydrophobicContact CB-CB 3.74Å; M166-L172 HydrophobicContact CB-CD2 4.28Å; M166-L172 HydrophobicContact CE-CB 4.44Å; M166-L172 HydrophobicContact SD-CD2 4.5Å; E167-L172 HydrophobicContact CG-CB 4.28Å; L172-L177 HydrophobicContact CD1-CD2 3.76Å; L172-L180 HydrophobicContact CD1-CB 3.74Å; L172-L180 HydrophobicContact CD1-CD2 3.75Å; L172-L180 HydrophobicContact CD1-CG 4.37Å; L172-L180 HydrophobicContact CD2-CD2 4.49Å
173A84.9Confident83.9Confident31 Ų3147.7 Ų47.726%0.25625%0.249SC..BIsolated β-bridgetrans-159.1166.5173.200000110Y121 N175 N176 L177Y121-A173 VanDerWaalsContact CE2-C 3.41Å; Y121-A173 WeakPolarHBondContact OH-CA 3.43Å; A173-N175 PolarHBondContact O-N 3.4Å; A173-N175 VanDerWaalsContact O-N 3.12Å; A173-N176 HydrophobicContact CB-CB 4.19Å; A173-N176 PolarHBondContact N-O 3.36Å; A173-N176 CarbonylContact O-C 3.55Å; A173-N176 VanDerWaalsContact O-C 3.27Å; A173-N176 PolarHBondContact O-N 3.08Å; A173-N176 VanDerWaalsContact O-O 3.06Å; A173-L177 WeakPolarHBondContact O-CD2 3.48Å
174E83.1Confident83.7Confident110 Ų11047.7 Ų47.751%0.51425%0.249SC..THydrogen-bonded Turntrans-53-33.9176.3169159.4-131.600113.7Y121 Y198Y121-E174 HydrophobicContact CD1-CB 4.42Å; Y121-E174 HydrophobicContact CD2-CB 4Å; Y121-E174 HydrophobicContact CE2-CB 4.49Å; Y121-E174 HydrophobicContact CG-CB 3.95Å; E174-Y198 WeakPolarHBondContact CG-OH 3.31Å; E174-Y198 PolarHBondContact OE1-OH 3.49Å
175N76.8Confident83.6Confident145 Ų14550.4 Ų50.478%0.77526%0.263SS*.THydrogen-bonded Turntrans-103.58.2177.367.9-26.4000114.1A173A173-N175 PolarHBondContact O-N 3.4Å; A173-N175 VanDerWaalsContact O-N 3.12Å
176N82.1Confident83.5Confident57 Ų5755 Ų5531%0.30528%0.284SS..BIsolated β-bridgetrans-143.390.2178.8-177.220.9000110.3T170 A173T170-N176 PolarHBondContact O-ND2 2.87Å; A173-N176 HydrophobicContact CB-CB 4.19Å; A173-N176 PolarHBondContact N-O 3.36Å; A173-N176 CarbonylContact O-C 3.55Å; A173-N176 VanDerWaalsContact O-C 3.27Å; A173-N176 PolarHBondContact O-N 3.08Å; A173-N176 VanDerWaalsContact O-O 3.06Å
177L86.9Confident83.4Confident2 Ų256.4 Ų56.41%0.0129%0.293CS..  trans-108.82.4-180-59.7176000112.6Y121 M124 L172 A173 T179 L180 K181 I195 Y198 E199Y121-L177 HydrophobicContact CD2-CD2 4.36Å; Y121-L177 HydrophobicContact CE2-CD2 3.91Å; M124-L177 HydrophobicContact CE-CD1 4.05Å; M124-L177 HydrophobicContact CE-CD2 3.88Å; L172-L177 HydrophobicContact CD1-CD2 3.76Å; A173-L177 WeakPolarHBondContact O-CD2 3.48Å; L177-T179 PolarHBondContact O-N 2.82Å; L177-L180 CarbonylContact O-C 3.51Å; L177-L180 PolarHBondContact O-N 3.31Å; L177-L180 VanDerWaalsContact O-N 3.1Å; L177-K181 WeakPolarHBondContact O-CG 3.3Å; L177-K181 PolarHBondContact O-N 3Å; L177-I195 HydrophobicContact CB-CG2 4.14Å; L177-I195 HydrophobicContact CD1-CG2 3.87Å; L177-Y198 HydrophobicContact CD1-CD1 3.79Å; L177-Y198 HydrophobicContact CD1-CE1 3.83Å; L177-E199 HydrophobicContact CD1-CG 4.15Å
178E84.5Confident83Confident112 Ų11256.2 Ų56.252%0.52329%0.293SS..Hα-helixtrans-62.6-43.4-170.2-65.8-55.612800113.8L180 K181 S182E178-L180 VanDerWaalsContact C-N 3.32Å; E178-L180 PolarHBondContact O-N 2.79Å; E178-K181 PolarHBondContact O-N 3.18Å; E178-K181 WeakPolarHBondContact OE1-CD 3.44Å; E178-K181 IonicContact OE1-NZ 2.69Å; E178-K181 PolarHBondContact OE1-NZ 3.1Å; E178-S182 WeakPolarHBondContact O-CB 3.49Å; E178-S182 PolarHBondContact O-N 3.12Å
179T83.8Confident82.8Confident28 Ų2857.5 Ų57.517%0.17230%0.299CS..Hα-helixtrans-61-42.5173.6-60.20000111.1E147 M166 M171 L177 S182 I183E147-T179 WeakPolarHBondContact OE2-CG2 3.38Å; M166-T179 HydrophobicContact CE-CG2 3.89Å; M171-T179 HydrophobicContact CE-CG2 4.03Å; L177-T179 PolarHBondContact O-N 2.82Å; T179-S182 PolarHBondContact O-N 2.82Å; T179-I183 HydrophobicContact CG2-CD1 3.94Å; T179-I183 WeakPolarHBondContact O-CD1 3.48Å; T179-I183 VanDerWaalsContact O-CG1 3.28Å; T179-I183 WeakPolarHBondContact O-CG1 3.26Å; T179-I183 PolarHBondContact O-N 2.84Å; T179-I183 VanDerWaalsContact O-N 3.1Å
180L86.6Confident82.9Confident0 Ų057.7 Ų57.70%031%0.31CS..Hα-helixtrans-68-41.6178.3-179.960.3000112.1L125 L128 F140 F163 L172 L177 E178 S182 I183 C184 I195L125-L180 HydrophobicContact CD2-CD2 3.51Å; L128-L180 HydrophobicContact CD1-CD2 3.9Å; F140-L180 HydrophobicContact CE1-CD1 3.78Å; F140-L180 HydrophobicContact CZ-CD1 4.34Å; F163-L180 HydrophobicContact CE1-CD1 3.62Å; F163-L180 HydrophobicContact CE1-CD2 4.36Å; F163-L180 HydrophobicContact CZ-CD1 4.25Å; L172-L180 HydrophobicContact CD1-CB 3.74Å; L172-L180 HydrophobicContact CD1-CD2 3.75Å; L172-L180 HydrophobicContact CD1-CG 4.37Å; L172-L180 HydrophobicContact CD2-CD2 4.49Å; L177-L180 CarbonylContact O-C 3.51Å; L177-L180 PolarHBondContact O-N 3.31Å; L177-L180 VanDerWaalsContact O-N 3.1Å; E178-L180 VanDerWaalsContact C-N 3.32Å; E178-L180 PolarHBondContact O-N 2.79Å; L180-S182 PolarHBondContact O-N 2.96Å; L180-I183 PolarHBondContact O-N 2.73Å; L180-C184 WeakPolarHBondContact O-CB 3.19Å; L180-C184 PolarHBondContact O-N 3.07Å; L180-C184 PolarHBondContact O-SG 2.97Å; L180-C184 VanDerWaalsContact O-SG 3.33Å; L180-I195 HydrophobicContact CD2-CD1 4.07Å; L180-I195 HydrophobicContact CG-CD1 3.83Å
181K86.1Confident83Confident32 Ų3252.1 Ų52.114%0.13928%0.276CS..Hα-helixtrans-57-48.3172.5-74.8165.5161.9167.90111.7L177 E178 I183 C184 D185 L192 I195 E199L177-K181 WeakPolarHBondContact O-CG 3.3Å; L177-K181 PolarHBondContact O-N 3Å; E178-K181 PolarHBondContact O-N 3.18Å; E178-K181 WeakPolarHBondContact OE1-CD 3.44Å; E178-K181 IonicContact OE1-NZ 2.69Å; E178-K181 PolarHBondContact OE1-NZ 3.1Å; K181-I183 VanDerWaalsContact C-N 3.3Å; K181-I183 PolarHBondContact O-N 3.21Å; K181-C184 PolarHBondContact O-N 3.15Å; K181-D185 PolarHBondContact O-N 2.86Å; K181-L192 HydrophobicContact CB-CD1 3.88Å; K181-L192 HydrophobicContact CG-CD1 3.88Å; K181-I195 HydrophobicContact CD-CG2 4.45Å; K181-I195 HydrophobicContact CG-CG2 3.81Å; K181-E199 VanDerWaalsContact CE-CD 3.47Å; K181-E199 WeakPolarHBondContact CE-OE1 3.47Å; K181-E199 WeakPolarHBondContact CE-OE2 3.29Å; K181-E199 IonicContact NZ-OE1 2.8Å; K181-E199 PolarHBondContact NZ-OE1 3.46Å; K181-E199 IonicContact NZ-OE2 2.66Å; K181-E199 PolarHBondContact NZ-OE2 2.95Å
182S84.9Confident83Confident67 Ų6751.9 Ų51.947%0.46928%0.275SS..Hα-helixtrans-59.7-39.6178.9-179.90000112.2E178 T179 L180 Q186E178-S182 WeakPolarHBondContact O-CB 3.49Å; E178-S182 PolarHBondContact O-N 3.12Å; T179-S182 PolarHBondContact O-N 2.82Å; L180-S182 PolarHBondContact O-N 2.96Å; S182-Q186 WeakPolarHBondContact O-CG 3.35Å; S182-Q186 PolarHBondContact O-N 3.03Å; S182-Q186 PolarHBondContact O-NE2 3.41Å
183I84.1Confident82.7Confident6 Ų652.9 Ų52.93%0.03129%0.286CS..Hα-helixtrans-72-44.5175.3-63.4161.9000110.6F140 L143 L144 M166 T179 L180 K181 D185 Q186 V187F140-I183 HydrophobicContact CD1-CG2 3.4Å; F140-I183 VanDerWaalsContact CD1-CG2 3.4Å; F140-I183 HydrophobicContact CD2-CG2 4.24Å; F140-I183 HydrophobicContact CE1-CB 4.31Å; F140-I183 HydrophobicContact CE1-CG2 3.47Å; F140-I183 VanDerWaalsContact CE1-CG2 3.47Å; F140-I183 HydrophobicContact CE2-CG2 4.29Å; F140-I183 HydrophobicContact CG-CG2 3.81Å; F140-I183 HydrophobicContact CZ-CG2 3.93Å; L143-I183 HydrophobicContact CB-CG1 4.5Å; L143-I183 HydrophobicContact CD1-CG2 4.05Å; L144-I183 HydrophobicContact CD1-CD1 4.45Å; L144-I183 HydrophobicContact CD2-CD1 3.52Å; L144-I183 HydrophobicContact CG-CD1 3.82Å; M166-I183 HydrophobicContact CE-CD1 4.16Å; T179-I183 HydrophobicContact CG2-CD1 3.94Å; T179-I183 WeakPolarHBondContact O-CD1 3.48Å; T179-I183 VanDerWaalsContact O-CG1 3.28Å; T179-I183 WeakPolarHBondContact O-CG1 3.26Å; T179-I183 PolarHBondContact O-N 2.84Å; T179-I183 VanDerWaalsContact O-N 3.1Å; L180-I183 PolarHBondContact O-N 2.73Å; K181-I183 VanDerWaalsContact C-N 3.3Å; K181-I183 PolarHBondContact O-N 3.21Å; I183-D185 PolarHBondContact O-N 2.91Å; I183-Q186 PolarHBondContact O-N 2.79Å; I183-V187 HydrophobicContact CG2-CG2 4.09Å; I183-V187 WeakPolarHBondContact O-CB 3.23Å; I183-V187 WeakPolarHBondContact O-CG2 3.09Å; I183-V187 PolarHBondContact O-N 3.39Å
184C85.5Confident82.6Confident0 Ų054 Ų540%029%0.286CS..Hα-helixtrans-61.4-41.1177.3-75.50000112.8L180 K181 Q186 V187 N188 L191 L192 I195L180-C184 WeakPolarHBondContact O-CB 3.19Å; L180-C184 PolarHBondContact O-N 3.07Å; L180-C184 PolarHBondContact O-SG 2.97Å; L180-C184 VanDerWaalsContact O-SG 3.33Å; K181-C184 PolarHBondContact O-N 3.15Å; C184-Q186 VanDerWaalsContact C-N 3.26Å; C184-Q186 PolarHBondContact O-N 2.8Å; C184-V187 PolarHBondContact O-N 2.92Å; C184-N188 CarbonylContact O-C 3.59Å; C184-N188 WeakPolarHBondContact O-CA 3.44Å; C184-N188 PolarHBondContact O-N 3.15Å; C184-L191 HydrophobicContact CB-CB 4.17Å; C184-L192 HydrophobicContact CB-CB 4.44Å; C184-I195 HydrophobicContact CB-CD1 4.22Å
185D83.4Confident82.7Confident69 Ų6948.8 Ų48.837%0.36926%0.261SS..Hα-helixtrans-62.8-33.9177-17360.5000112.6K181 I183 K189 L192K181-D185 PolarHBondContact O-N 2.86Å; I183-D185 PolarHBondContact O-N 2.91Å; D185-K189 IonicContact OD1-NZ 2.68Å; D185-K189 PolarHBondContact OD1-NZ 2.85Å; D185-K189 IonicContact OD2-NZ 3.47Å; D185-K189 PolarHBondContact OD2-NZ 2.87Å; D185-L192 HydrophobicContact CB-CD2 4.27Å
186Q80.4Confident83Confident119 Ų11946.1 Ų46.156%0.55624%0.244SC*.Hα-helixtrans-79.9-35177.9-71.6175.780.700113.5L143 S182 I183 C184L143-Q186 HydrophobicContact CD1-CB 3.86Å; S182-Q186 WeakPolarHBondContact O-CG 3.35Å; S182-Q186 PolarHBondContact O-N 3.03Å; S182-Q186 PolarHBondContact O-NE2 3.41Å; I183-Q186 PolarHBondContact O-N 2.79Å; C184-Q186 VanDerWaalsContact C-N 3.26Å; C184-Q186 PolarHBondContact O-N 2.8Å
187V81.8Confident83.1Confident29 Ų2947.2 Ų47.218%0.17625%0.25CS..Hα-helixtrans-91.3-53.9-177.31800000112E136 F140 L143 I183 C184E136-V187 HydrophobicContact CB-CG1 3.51Å; E136-V187 HydrophobicContact CG-CG1 3.68Å; F140-V187 HydrophobicContact CD2-CB 4.2Å; F140-V187 HydrophobicContact CD2-CG1 3.91Å; F140-V187 HydrophobicContact CD2-CG2 4.01Å; F140-V187 HydrophobicContact CE2-CB 4.03Å; F140-V187 HydrophobicContact CE2-CG1 3.91Å; F140-V187 HydrophobicContact CE2-CG2 4.25Å; L143-V187 HydrophobicContact CD1-CG2 3.64Å; I183-V187 HydrophobicContact CG2-CG2 4.09Å; I183-V187 WeakPolarHBondContact O-CB 3.23Å; I183-V187 WeakPolarHBondContact O-CG2 3.09Å; I183-V187 PolarHBondContact O-N 3.39Å; C184-V187 PolarHBondContact O-N 2.92Å
188N79.3Confident82.9Confident41 Ų4148 Ų4822%0.21925%0.253CS..  trans-158.1111.9-178.6-176.9-9.9000112.9E136 C184 S190 L191E136-N188 VanDerWaalsContact OE1-CB 3.24Å; E136-N188 WeakPolarHBondContact OE1-CB 3.36Å; E136-N188 PolarHBondContact OE1-ND2 3.16Å; C184-N188 CarbonylContact O-C 3.59Å; C184-N188 WeakPolarHBondContact O-CA 3.44Å; C184-N188 PolarHBondContact O-N 3.15Å; N188-S190 VanDerWaalsContact C-N 3.26Å; N188-S190 PolarHBondContact ND2-OG 3.47Å; N188-S190 PolarHBondContact O-N 2.78Å; N188-S190 PolarHBondContact OD1-N 2.78Å; N188-S190 PolarHBondContact OD1-OG 2.92Å; N188-L191 HydrophobicContact CB-CD1 3.86Å; N188-L191 HydrophobicContact CB-CG 4.01Å; N188-L191 VanDerWaalsContact O-CB 3.32Å; N188-L191 WeakPolarHBondContact O-CB 3.34Å; N188-L191 PolarHBondContact O-N 3.25Å
189K79.3Confident82.8Confident137 Ų13745.3 Ų45.360%0.59624%0.241SC*.Hα-helixtrans-65.5-18-178.3-60.5-174-179.1-102.30114.8D185 L191 L192 G193D185-K189 IonicContact OD1-NZ 2.68Å; D185-K189 PolarHBondContact OD1-NZ 2.85Å; D185-K189 IonicContact OD2-NZ 3.47Å; D185-K189 PolarHBondContact OD2-NZ 2.87Å; K189-L191 VanDerWaalsContact C-N 3.29Å; K189-L192 PolarHBondContact O-N 3.5Å; K189-G193 PolarHBondContact O-N 3.39Å
190S78.8Confident82.6Confident71 Ų7149.8 Ų49.850%0.49725%0.254SS..Hα-helixtrans-71.7-26.5172.8690000112.4N188N188-S190 VanDerWaalsContact C-N 3.26Å; N188-S190 PolarHBondContact ND2-OG 3.47Å; N188-S190 PolarHBondContact O-N 2.78Å; N188-S190 PolarHBondContact OD1-N 2.78Å; N188-S190 PolarHBondContact OD1-OG 2.92Å
191L82.4Confident82Confident1 Ų151.8 Ų51.81%0.00527%0.268CS..Hα-helixtrans-71.1-35.9173.9-57.1176.9000111.3L128 E131 V132 F140 C184 N188 K189 G193 K194 I195L128-L191 HydrophobicContact CD2-CB 3.95Å; L128-L191 HydrophobicContact CD2-CD2 3.92Å; L128-L191 HydrophobicContact CD2-CG 4.49Å; E131-L191 HydrophobicContact CB-CD2 4.08Å; V132-L191 HydrophobicContact CG2-CD1 3.41Å; V132-L191 VanDerWaalsContact CG2-CD1 3.41Å; V132-L191 HydrophobicContact CG2-CD2 4.31Å; F140-L191 HydrophobicContact CE2-CD1 4.22Å; F140-L191 HydrophobicContact CZ-CD1 4.42Å; C184-L191 HydrophobicContact CB-CB 4.17Å; N188-L191 HydrophobicContact CB-CD1 3.86Å; N188-L191 HydrophobicContact CB-CG 4.01Å; N188-L191 VanDerWaalsContact O-CB 3.32Å; N188-L191 WeakPolarHBondContact O-CB 3.34Å; N188-L191 PolarHBondContact O-N 3.25Å; K189-L191 VanDerWaalsContact C-N 3.29Å; L191-G193 PolarHBondContact O-N 3.06Å; L191-K194 WeakPolarHBondContact O-CB 3.34Å; L191-K194 PolarHBondContact O-N 3.37Å; L191-I195 PolarHBondContact O-N 3.28Å
192L81.2Confident81.2Confident28 Ų2851.8 Ų51.815%0.14727%0.272CS..Hα-helixtrans-59.6-44.9176.3-176.366.5000111.5K181 C184 D185 K189 K194 I195 E196K181-L192 HydrophobicContact CB-CD1 3.88Å; K181-L192 HydrophobicContact CG-CD1 3.88Å; C184-L192 HydrophobicContact CB-CB 4.44Å; D185-L192 HydrophobicContact CB-CD2 4.27Å; K189-L192 PolarHBondContact O-N 3.5Å; L192-K194 PolarHBondContact O-N 3.09Å; L192-I195 WeakPolarHBondContact O-CA 3.18Å; L192-I195 WeakPolarHBondContact O-CB 3.47Å; L192-I195 PolarHBondContact O-N 2.8Å; L192-E196 PolarHBondContact O-N 2.91Å
193G80.1Confident80.2Confident25 Ų2552 Ų5226%0.25827%0.271SS..Hα-helixtrans-57.3-34.4178.100000113.6K189 L191 E196 D197K189-G193 PolarHBondContact O-N 3.39Å; L191-G193 PolarHBondContact O-N 3.06Å; G193-E196 PolarHBondContact O-N 2.6Å; G193-D197 WeakPolarHBondContact O-CB 3.31Å; G193-D197 PolarHBondContact O-N 3.27Å
194K83.3Confident79.1Confident55 Ų5556.8 Ų56.824%0.23929%0.293CS..Hα-helixtrans-68.8-33.8174.5-74.5-179.6157.5-177.10113.7K127 L128 E131 L191 L192 Y198K127-K194 PolarHBondContact O-NZ 3.19Å; L128-K194 HydrophobicContact CD2-CB 4.08Å; L128-K194 HydrophobicContact CD2-CD 3.98Å; E131-K194 IonicContact OE1-NZ 3.28Å; E131-K194 PolarHBondContact OE1-NZ 3.13Å; E131-K194 VanDerWaalsContact OE2-CE 3.25Å; E131-K194 WeakPolarHBondContact OE2-CE 3.07Å; E131-K194 IonicContact OE2-NZ 2.97Å; E131-K194 PolarHBondContact OE2-NZ 2.99Å; L191-K194 WeakPolarHBondContact O-CB 3.34Å; L191-K194 PolarHBondContact O-N 3.37Å; L192-K194 PolarHBondContact O-N 3.09Å; K194-Y198 WeakPolarHBondContact O-CB 3.41Å; K194-Y198 PolarHBondContact O-N 2.89Å
195I85.4Confident77.9Confident0 Ų061.5 Ų61.50%031%0.311CS..Hα-helixtrans-70.6-43.2175.9-62168.7000109.2M124 L128 L177 L180 K181 C184 L191 L192 Y198 E199M124-I195 HydrophobicContact SD-CG1 4.2Å; L128-I195 HydrophobicContact CD1-CD1 4.03Å; L128-I195 HydrophobicContact CD1-CG1 3.91Å; L177-I195 HydrophobicContact CB-CG2 4.14Å; L177-I195 HydrophobicContact CD1-CG2 3.87Å; L180-I195 HydrophobicContact CD2-CD1 4.07Å; L180-I195 HydrophobicContact CG-CD1 3.83Å; K181-I195 HydrophobicContact CD-CG2 4.45Å; K181-I195 HydrophobicContact CG-CG2 3.81Å; C184-I195 HydrophobicContact CB-CD1 4.22Å; L191-I195 PolarHBondContact O-N 3.28Å; L192-I195 WeakPolarHBondContact O-CA 3.18Å; L192-I195 WeakPolarHBondContact O-CB 3.47Å; L192-I195 PolarHBondContact O-N 2.8Å; I195-Y198 WeakPolarHBondContact O-CB 3.44Å; I195-Y198 PolarHBondContact O-N 3.43Å; I195-E199 WeakPolarHBondContact O-CG 3.09Å; I195-E199 PolarHBondContact O-N 2.95Å
196E83.6Confident76.5Confident89 Ų8966.8 Ų66.842%0.41633%0.326SS..Hα-helixtrans-63.8-41.7174.6-66.6177.6177.100112.6L192 G193 Y198 E199 R200L192-E196 PolarHBondContact O-N 2.91Å; G193-E196 PolarHBondContact O-N 2.6Å; E196-Y198 VanDerWaalsContact C-N 3.32Å; E196-Y198 PolarHBondContact O-N 3.24Å; E196-E199 PolarHBondContact O-N 3.12Å; E196-R200 WeakPolarHBondContact O-CB 3.33Å; E196-R200 PolarHBondContact O-N 2.74Å
197D82.9Confident74.9Confident81 Ų8167.1 Ų67.143%0.43333%0.329SS..Hα-helixtrans-64.3-37.1175-75-14.6000111.9G193 R200 S201G193-D197 WeakPolarHBondContact O-CB 3.31Å; G193-D197 PolarHBondContact O-N 3.27Å; D197-R200 IonicContact OD1-CZ 3.46Å; D197-R200 IonicContact OD1-NH1 2.68Å; D197-R200 PolarHBondContact OD1-NH1 2.94Å; D197-R200 IonicContact OD1-NH2 3.38Å; D197-R200 PolarHBondContact OD1-NH2 2.87Å; D197-S201 VanDerWaalsContact O-CB 3.26Å; D197-S201 WeakPolarHBondContact O-CB 3.23Å; D197-S201 PolarHBondContact O-N 3.13Å; D197-S201 PolarHBondContact O-OG 3.24Å
198Y84.3Confident73.5Confident18 Ų1870.2 Ų70.27%0.07135%0.351CS..Hα-helixtrans-63.5-47.2172.2167.5-93.5000111.8P120 M124 E174 L177 K194 I195 E196 S201 S202P120-Y198 HydrophobicContact CB-CE2 3.93Å; M124-Y198 HydrophobicContact CB-CD2 3.89Å; M124-Y198 HydrophobicContact CB-CG 4.19Å; M124-Y198 HydrophobicContact CE-CD1 4.25Å; M124-Y198 HydrophobicContact CE-CG 4.46Å; M124-Y198 HydrophobicContact CG-CD2 4.15Å; M124-Y198 HydrophobicContact CG-CG 3.92Å; E174-Y198 WeakPolarHBondContact CG-OH 3.31Å; E174-Y198 PolarHBondContact OE1-OH 3.49Å; L177-Y198 HydrophobicContact CD1-CD1 3.79Å; L177-Y198 HydrophobicContact CD1-CE1 3.83Å; K194-Y198 WeakPolarHBondContact O-CB 3.41Å; K194-Y198 PolarHBondContact O-N 2.89Å; I195-Y198 WeakPolarHBondContact O-CB 3.44Å; I195-Y198 PolarHBondContact O-N 3.43Å; E196-Y198 VanDerWaalsContact C-N 3.32Å; E196-Y198 PolarHBondContact O-N 3.24Å; Y198-S201 PolarHBondContact O-N 2.96Å; Y198-S202 WeakPolarHBondContact O-CB 3.41Å; Y198-S202 PolarHBondContact O-N 2.74Å; Y198-S202 PolarHBondContact O-OG 3.28Å
199E81.2Confident71.9Confident56 Ų5675.5 Ų75.526%0.26238%0.379SS..Hα-helixtrans-66.4-37.3178.8-73.1-177157.800112.8L177 K181 I195 E196 S202 T203L177-E199 HydrophobicContact CD1-CG 4.15Å; K181-E199 VanDerWaalsContact CE-CD 3.47Å; K181-E199 WeakPolarHBondContact CE-OE1 3.47Å; K181-E199 WeakPolarHBondContact CE-OE2 3.29Å; K181-E199 IonicContact NZ-OE1 2.8Å; K181-E199 PolarHBondContact NZ-OE1 3.46Å; K181-E199 IonicContact NZ-OE2 2.66Å; K181-E199 PolarHBondContact NZ-OE2 2.95Å; I195-E199 WeakPolarHBondContact O-CG 3.09Å; I195-E199 PolarHBondContact O-N 2.95Å; E196-E199 PolarHBondContact O-N 3.12Å; E199-S202 PolarHBondContact O-N 3.18Å; E199-S202 PolarHBondContact O-OG 2.97Å; E199-S202 VanDerWaalsContact O-OG 3.11Å; E199-T203 VanDerWaalsContact O-CB 3.3Å; E199-T203 WeakPolarHBondContact O-CB 3.31Å; E199-T203 PolarHBondContact O-N 2.98Å; E199-T203 PolarHBondContact O-OG1 2.84Å
200R79.8Confident70.1Confident121 Ų12177 Ų7746%0.45739%0.388SS..Hα-helixtrans-62.8-48.3171.9-160.5-178.4-50.7110.812.4110.5E196 D197 S202 T203 E204E196-R200 WeakPolarHBondContact O-CB 3.33Å; E196-R200 PolarHBondContact O-N 2.74Å; D197-R200 IonicContact OD1-CZ 3.46Å; D197-R200 IonicContact OD1-NH1 2.68Å; D197-R200 PolarHBondContact OD1-NH1 2.94Å; D197-R200 IonicContact OD1-NH2 3.38Å; D197-R200 PolarHBondContact OD1-NH2 2.87Å; R200-S202 VanDerWaalsContact C-N 3.34Å; R200-S202 PolarHBondContact O-N 3.06Å; R200-T203 PolarHBondContact O-N 2.79Å; R200-E204 WeakPolarHBondContact O-CB 3.44Å; R200-E204 WeakPolarHBondContact O-CG 3.34Å; R200-E204 PolarHBondContact O-N 2.74Å
201S75.2Confident68.1Low43 Ų4376.4 Ų76.430%0.30139%0.393SS..Hα-helixtrans-63.4-34.1178.7-60.30000113.7D197 Y198 R205D197-S201 VanDerWaalsContact O-CB 3.26Å; D197-S201 WeakPolarHBondContact O-CB 3.23Å; D197-S201 PolarHBondContact O-N 3.13Å; D197-S201 PolarHBondContact O-OG 3.24Å; Y198-S201 PolarHBondContact O-N 2.96Å; S201-R205 VanDerWaalsContact O-CG 3.27Å; S201-R205 WeakPolarHBondContact O-CG 3.44Å; S201-R205 PolarHBondContact O-N 2.85Å; S201-R205 PolarHBondContact O-NE 3.18Å
202S68.1Low65.8Low31 Ų3187.7 Ų87.722%0.21744%0.435CS..Hα-helixtrans-78.1-33.1177.868.90000111.8Y198 E199 R200 R206Y198-S202 WeakPolarHBondContact O-CB 3.41Å; Y198-S202 PolarHBondContact O-N 2.74Å; Y198-S202 PolarHBondContact O-OG 3.28Å; E199-S202 PolarHBondContact O-N 3.18Å; E199-S202 PolarHBondContact O-OG 2.97Å; E199-S202 VanDerWaalsContact O-OG 3.11Å; R200-S202 VanDerWaalsContact C-N 3.34Å; R200-S202 PolarHBondContact O-N 3.06Å; S202-R206 WeakPolarHBondContact O-CG 3.48Å; S202-R206 PolarHBondContact O-N 3.28Å; S202-R206 VanDerWaalsContact O-N 3.12Å
203T63.8Low63.5Low71 Ų7196 Ų9644%0.43647%0.473SS..Hα-helixtrans-67.8-45.6171.8-56.50000111.4E199 R200 R205 R206 M207E199-T203 VanDerWaalsContact O-CB 3.3Å; E199-T203 WeakPolarHBondContact O-CB 3.31Å; E199-T203 PolarHBondContact O-N 2.98Å; E199-T203 PolarHBondContact O-OG1 2.84Å; R200-T203 PolarHBondContact O-N 2.79Å; T203-R205 VanDerWaalsContact C-N 3.33Å; T203-R205 PolarHBondContact O-N 3.43Å; T203-R206 WeakPolarHBondContact O-CB 3.49Å; T203-R206 PolarHBondContact O-N 3.45Å; T203-M207 HydrophobicContact CG2-SD 4.34Å; T203-M207 WeakPolarHBondContact O-CG 3.18Å; T203-M207 PolarHBondContact O-N 3.34Å
204E61.8Low61.2Low107 Ų107104 Ų10450%0.550%0.504SS..Hα-helixtrans-61.3-39.2175.9-73.9169.9-175.500111.9R200 M207 S208R200-E204 WeakPolarHBondContact O-CB 3.44Å; R200-E204 WeakPolarHBondContact O-CG 3.34Å; R200-E204 PolarHBondContact O-N 2.74Å; E204-M207 PolarHBondContact O-N 3.11Å; E204-S208 WeakPolarHBondContact O-CB 3.35Å; E204-S208 PolarHBondContact O-N 3.4Å; E204-S208 PolarHBondContact O-OG 3.28Å
205R60.1Low58.6Low99 Ų99109.5 Ų109.537%0.37454%0.535SS..Hα-helixtrans-63.9-40.9173.6-75.8175.7-132.2-163.4-0.6112.7P120 S201 T203 S208 L209P120-R205 VanDerWaalsContact CG-NH1 3.28Å; S201-R205 VanDerWaalsContact O-CG 3.27Å; S201-R205 WeakPolarHBondContact O-CG 3.44Å; S201-R205 PolarHBondContact O-N 2.85Å; S201-R205 PolarHBondContact O-NE 3.18Å; T203-R205 VanDerWaalsContact C-N 3.33Å; T203-R205 PolarHBondContact O-N 3.43Å; R205-S208 PolarHBondContact O-N 3.33Å; R205-L209 PolarHBondContact O-N 3.37Å
206R54.6Low55.9Low180 Ų180114.2 Ų114.268%0.67957%0.566SS**Hα-helixtrans-60.5-46174.2-77.6173163.2176.7-3.5111.7S202 T203 S208 L209S202-R206 WeakPolarHBondContact O-CG 3.48Å; S202-R206 PolarHBondContact O-N 3.28Å; S202-R206 VanDerWaalsContact O-N 3.12Å; T203-R206 WeakPolarHBondContact O-CB 3.49Å; T203-R206 PolarHBondContact O-N 3.45Å; R206-S208 PolarHBondContact O-N 3.48Å; R206-L209 PolarHBondContact O-N 2.9Å
207M46.7Very low53.5Low127 Ų127116.5 Ų116.563%0.62659%0.589SS**Hα-helixtrans-66.6-34.5176.4-65.1178.170.700112.9T203 E204 L209 E210 G211T203-M207 HydrophobicContact CG2-SD 4.34Å; T203-M207 WeakPolarHBondContact O-CG 3.18Å; T203-M207 PolarHBondContact O-N 3.34Å; E204-M207 PolarHBondContact O-N 3.11Å; M207-L209 VanDerWaalsContact C-N 3.27Å; M207-L209 PolarHBondContact O-N 2.97Å; M207-E210 PolarHBondContact O-N 3.02Å; M207-G211 PolarHBondContact O-N 2.84Å
208S52.1Low51.1Low93 Ų93117.7 Ų117.765%0.6560%0.603SS**Hα-helixtrans-66.5-28.4179.8-57.70000113.2E204 R205 R206E204-S208 WeakPolarHBondContact O-CB 3.35Å; E204-S208 PolarHBondContact O-N 3.4Å; E204-S208 PolarHBondContact O-OG 3.28Å; R205-S208 PolarHBondContact O-N 3.33Å; R206-S208 PolarHBondContact O-N 3.48Å
209L45.5Very low48.4Very low152 Ų152123.5 Ų123.580%0.79664%0.64SS**Hα-helixtrans-78.8-19.2176.9-70.6165.8000113.1R205 R206 M207R205-L209 PolarHBondContact O-N 3.37Å; R206-L209 PolarHBondContact O-N 2.9Å; M207-L209 VanDerWaalsContact C-N 3.27Å; M207-L209 PolarHBondContact O-N 2.97Å
210E42Very low45.9Very low170 Ų170129.7 Ų129.779%0.79467%0.674SS**Hα-helixtrans-93-9.2177.3-64.2-177.715200112.5M207 R212M207-E210 PolarHBondContact O-N 3.02Å; E210-R212 PolarHBondContact O-N 3.03Å; E210-R212 VanDerWaalsContact O-N 3.1Å
211G35.4Very low43.6Very low57 Ų57130.9 Ų130.959%0.58869%0.69SS**  trans-84.259.8-17300000116.6M207M207-G211 PolarHBondContact O-N 2.84Å
212R34.9Very low41.5Very low238 Ų238137.4 Ų137.490%0.89872%0.715SS**  trans-140.861.8165.1-79.8-161-179.2-172.24.3114.2E210E210-R212 PolarHBondContact O-N 3.03Å; E210-R212 VanDerWaalsContact O-N 3.1Å
213E33.6Very low39.5Very low202 Ų202145 Ų14594%0.94475%0.75SS**  trans-166.699.2147.9-112.6170.2-151.100110
214E31.1Very low37.6Very low194 Ų194146.3 Ų146.391%0.90776%0.761SS**  trans-106.8135.9168.7-81.1-164.2157.400111
215L28.1Very low36.1Very low170 Ų170149.3 Ų149.389%0.8978%0.78SS**  trans-136.2152.4155.9-83.2172.5000108.7
216P29.8Very low34.5Very low100 Ų100153.3 Ų153.365%0.64980%0.8SS**  trans-97160.2-142.92.316.7000115.3S218P216-S218 PolarHBondContact O-N 3.32Å
217P33.1Very low33.1Very low137 Ų137152.8 Ų152.889%0.8981%0.808SS**  trans-81.5103.8-178.132.2-33.8000112.3
218S31.5Very low32.2Very low106 Ų106151.2 Ų151.274%0.74182%0.815SS**  trans-156.744.1172.859.20000117P216P216-S218 PolarHBondContact O-N 3.32Å
219V27.7Very low31Very low140 Ų140155.5 Ų155.585%0.84883%0.825SS**  trans-152.185.7151.2-112.40000110.7
220L29.7Very low30.1Very low186 Ų186156 Ų15697%0.97483%0.827SS**  trans-121.565.6159.9-90.7172.7000108.4
221D31.8Very low29.2Very low146 Ų146154.1 Ų154.178%0.78183%0.831SS**  trans-149.2158.1151.6-150.1-7000108.7
222E30.2Very low28.7Very low179 Ų179158.8 Ų158.884%0.83684%0.843SS**  trans62.671.5-178.8-57.7-160.7127.900118.6
223M25Very low28.4Very low191 Ų191151.7 Ų151.794%0.94183%0.83SS**  -157.285.7119.4-121.4-177.5177.500114.8
224S25.8Very low28.9Very low98 Ų98146.6 Ų146.669%0.68581%0.814SS**  trans11.3121145.1-53.10000118.4
225L30.1Very low28.8Very low171 Ų171147.8 Ų147.890%0.89581%0.81SS**  41.378.177.9-73.5168.6000114.4
226K25.9Very low28.9Very low182 Ų182147.8 Ų147.879%0.79181%0.806SS**  trans175132.4158.1-99.9158.1-172.7177.10106.7
227M25.3Very low29.3Very low170 Ų170152.3 Ų152.384%0.83782%0.818SS**  cis-142.1145.72.3-79.4-83.1-160.500107.8
228A27Very low29.3Very low94 Ų94153.2 Ų153.278%0.77782%0.815SS**  trans-113.3117.9151.700000107.1
229E26.9Very low29.8Very low183 Ų183153.6 Ų153.686%0.85582%0.818SS**  trans172157.1147.7-100.2175-166.800111.8
230L26.5Very low30.2Very low163 Ų163152.3 Ų152.385%0.85380%0.803SS**  trans72.3106.8177.3-49.1169.2000114.4
231C24.7Very low30.6Very low129 Ų129149.5 Ų149.587%0.87280%0.799SS**  cis-157147.749.8-79.30000114.3
232D25.1Very low31.1Very low156 Ų156151 Ų15183%0.83479%0.793SS**  trans-93.9164.1155.9-16026.4000107.5
233S28Very low31.6Very low89 Ų89148 Ų14862%0.62279%0.788SS**  cis-165.1-174.418.769.70000108.9
234P42.8Very low33.1Very low95 Ų95144 Ų14462%0.61778%0.778SS**  cis-133.1-172.2-43.131-10.4000112.3
235R29.2Very low35.4Very low218 Ų218143.9 Ų143.982%0.82377%0.77SS**  trans77.3141.6168.5-53.6178.2-174178.71115.5
236E31.8Very low38.3Very low171 Ų171143.6 Ų143.680%0.79976%0.761SS**  cis-133.6147.44.7-125.4144.6-132.800109.5D238E236-D238 PolarHBondContact O-N 3.29Å
237Q38Very low41.7Very low194 Ų194138.3 Ų138.391%0.90774%0.744SS**  trans-72.9122.9168.4-74176.6-51.200108.1
238D31.8Very low45.1Very low156 Ų156130.6 Ų130.683%0.83471%0.706SS**  trans-132116149.6-141.1-8.7000109.6E236 E240E236-D238 PolarHBondContact O-N 3.29Å; D238-E240 PolarHBondContact O-N 3.09Å
239S42.8Very low48.3Very low114 Ų114131.6 Ų131.680%0.79770%0.695SS**  trans-9387-172.354.60000110.1
240E35Very low51.6Low114 Ų114123.4 Ų123.453%0.53366%0.656SS.*  trans-121.390.6162.3-74.3-157.415000110.5D238 R242D238-E240 PolarHBondContact O-N 3.09Å; E240-R242 HydrophobicContact CB-CG 4.3Å; E240-R242 PolarHBondContact O-N 2.76Å; E240-R242 IonicContact OE1-CZ 3.9Å; E240-R242 IonicContact OE1-NE 2.95Å; E240-R242 PolarHBondContact OE1-NE 3.08Å; E240-R242 IonicContact OE1-NH1 3.42Å; E240-R242 PolarHBondContact OE1-NH1 2.86Å; E240-R242 IonicContact OE1-NH2 3.86Å; E240-R242 PolarHBondContact OE1-NH2 2.95Å; E240-R242 WeakPolarHBondContact OE2-CD 3.15Å; E240-R242 IonicContact OE2-CZ 2.79Å; E240-R242 IonicContact OE2-NE 3.52Å; E240-R242 PolarHBondContact OE2-NE 2.93Å; E240-R242 IonicContact OE2-NH1 3.43Å; E240-R242 PolarHBondContact OE2-NH1 3.35Å; E240-R242 IonicContact OE2-NH2 2.67Å
241S39Very low54.9Low126 Ų126123.5 Ų123.588%0.88165%0.65SS**  trans-73.454159.9660000110.5T243S241-T243 PolarHBondContact O-N 3.18Å
242R41.8Very low58.2Low178 Ų178119.8 Ų119.867%0.67262%0.621SS**  trans-69.9112.2161.7-75.3-177.6176.9149.64.5106.4E240 S244E240-R242 HydrophobicContact CB-CG 4.3Å; E240-R242 PolarHBondContact O-N 2.76Å; E240-R242 IonicContact OE1-CZ 3.9Å; E240-R242 IonicContact OE1-NE 2.95Å; E240-R242 PolarHBondContact OE1-NE 3.08Å; E240-R242 IonicContact OE1-NH1 3.42Å; E240-R242 PolarHBondContact OE1-NH1 2.86Å; E240-R242 IonicContact OE1-NH2 3.86Å; E240-R242 PolarHBondContact OE1-NH2 2.95Å; E240-R242 WeakPolarHBondContact OE2-CD 3.15Å; E240-R242 IonicContact OE2-CZ 2.79Å; E240-R242 IonicContact OE2-NE 3.52Å; E240-R242 PolarHBondContact OE2-NE 2.93Å; E240-R242 IonicContact OE2-NH1 3.43Å; E240-R242 PolarHBondContact OE2-NH1 3.35Å; E240-R242 IonicContact OE2-NH2 2.67Å; R242-S244 PolarHBondContact O-N 3.3Å
243T40.9Very low61.5Low117 Ų117118.7 Ų118.772%0.71861%0.609SS**  trans-61.789.6160.948.10000107.4S241 D245S241-T243 PolarHBondContact O-N 3.18Å; T243-D245 PolarHBondContact O-N 3.49Å; T243-D245 VanDerWaalsContact O-N 3.16Å
244S57.1Low64.7Low105 Ų105116.9 Ų116.973%0.73460%0.595SS**PPolyproline II helixtrans-62.2121.217958.20000108.3R242 K246R242-S244 PolarHBondContact O-N 3.3Å; S244-K246 PolarHBondContact O-N 3.02Å
245D74.1Confident67.3Low97 Ų97112.9 Ų112.952%0.51957%0.568SS.*PPolyproline II helixtrans-51.5128.5177.8-76.4-55.4000109.1T243 V247 K495T243-D245 PolarHBondContact O-N 3.49Å; T243-D245 VanDerWaalsContact O-N 3.16Å; D245-V247 WeakPolarHBondContact O-CG2 3.43Å; D245-V247 PolarHBondContact O-N 3.28Å; D245-K495 HydrophobicContact CB-CD 3.88Å; D245-K495 HydrophobicContact CB-CG 4.37Å; D245-K495 VanDerWaalsContact CG-CE 3.45Å; D245-K495 VanDerWaalsContact CG-NZ 3.32Å; D245-K495 IonicContact OD1-NZ 2.91Å; D245-K495 VanDerWaalsContact OD2-CE 3.31Å; D245-K495 WeakPolarHBondContact OD2-CE 3.46Å; D245-K495 IonicContact OD2-NZ 2.73Å; D245-K495 PolarHBondContact OD2-NZ 2.8Å
246K91Very high70.6Confident164 Ų164102.5 Ų102.571%0.71353%0.529SS*.PPolyproline II helixtrans-67.2122176-66.2177.6-178.3170.70107.6S244 K494 K495S244-K246 PolarHBondContact O-N 3.02Å; K246-K494 HydrophobicContact CB-CB 4.49Å; K246-K494 HydrophobicContact CB-CD 4.34Å; K246-K494 HydrophobicContact CB-CG 3.92Å; K246-K494 CarbonylContact O-C 3.52Å; K246-K494 WeakPolarHBondContact O-CA 3.48Å; K246-K494 WeakPolarHBondContact O-CB 3.37Å; K246-K495 PolarHBondContact O-N 3.38Å
247V96.2Very high73.8Confident71 Ų7196.5 Ų96.543%0.4350%0.499SS..BIsolated β-bridgetrans-111.1143.5-178.2-176.30000110.7D245 K494 K495 F497D245-V247 WeakPolarHBondContact O-CG2 3.43Å; D245-V247 PolarHBondContact O-N 3.28Å; V247-K494 WeakPolarHBondContact O-CD 3.38Å; V247-K495 WeakPolarHBondContact CA-O 3.49Å; V247-F497 HydrophobicContact CG1-CD2 3.59Å; V247-F497 HydrophobicContact CG1-CE2 3.93Å; V247-F497 HydrophobicContact CG2-CD2 4.39Å; V247-F497 HydrophobicContact CG2-CE2 3.88Å
248Y96.6Very high76.7Confident9 Ų987.3 Ų87.34%0.03546%0.456CS..  trans-68.3142.3169.3-71.7-72.9000111.5M250 P374 D420 L492 R493 K494 K495 L496Y248-M250 PolarHBondContact O-N 3.31Å; Y248-P374 HydrophobicContact CD1-CG 4.4Å; Y248-P374 HydrophobicContact CD2-CB 4.44Å; Y248-P374 HydrophobicContact CD2-CG 4.48Å; Y248-P374 HydrophobicContact CE2-CB 4.46Å; Y248-P374 HydrophobicContact CG-CG 4.2Å; Y248-D420 HydrophobicContact CE1-CB 4.18Å; Y248-D420 WeakPolarHBondContact OH-CB 3.35Å; Y248-D420 VanDerWaalsContact OH-CG 3.31Å; Y248-D420 PolarHBondContact OH-OD1 2.96Å; Y248-L492 HydrophobicContact CE2-CB 4.22Å; Y248-L492 HydrophobicContact CE2-CD2 3.84Å; Y248-L492 HydrophobicContact CE2-CG 4.46Å; Y248-L492 WeakPolarHBondContact OH-CA 3.47Å; Y248-R493 PolarHBondContact OH-N 3.35Å; Y248-K494 HydrophobicContact CD1-CB 4.16Å; Y248-K494 HydrophobicContact CD1-CD 3.95Å; Y248-K494 HydrophobicContact CD1-CG 4.43Å; Y248-K494 HydrophobicContact CD2-CB 3.65Å; Y248-K494 HydrophobicContact CE1-CB 4.12Å; Y248-K494 HydrophobicContact CE1-CD 4.16Å; Y248-K494 HydrophobicContact CE1-CG 4.28Å; Y248-K494 HydrophobicContact CE2-CB 3.63Å; Y248-K494 WeakPolarHBondContact CE2-O 3.3Å; Y248-K494 HydrophobicContact CG-CB 3.93Å; Y248-K494 HydrophobicContact CG-CD 4.31Å; Y248-K495 PolarHBondContact N-O 3.27Å; Y248-L496 HydrophobicContact CD2-CB 3.88Å; Y248-L496 HydrophobicContact CD2-CD1 3.99Å; Y248-L496 HydrophobicContact CD2-CG 4.42Å; Y248-L496 HydrophobicContact CE2-CB 4.37Å; Y248-L496 HydrophobicContact CG-CD1 4.39Å
249Q95.6Very high79.9Confident115 Ų11579.9 Ų79.954%0.53742%0.416SS..  trans-62.3136.2169.4-177174.5-68.500109.7K251 D330Q249-K251 HydrophobicContact CG-CB 4.26Å; Q249-K251 HydrophobicContact CG-CD 4.38Å; Q249-K251 HydrophobicContact CG-CG 4.2Å; Q249-D330 PolarHBondContact NE2-OD1 2.97Å; Q249-D330 WeakPolarHBondContact O-CB 3.48Å
250M96.4Very high82.5Confident10 Ų1074.4 Ų74.45%0.04938%0.378CS..  trans-14959.8179-158.56261.800109.7Y248 R255 D330 C331 P374 L496 F497 F498 P499Y248-M250 PolarHBondContact O-N 3.31Å; M250-R255 PolarHBondContact O-NE 2.64Å; M250-R255 PolarHBondContact O-NH1 2.9Å; M250-R255 PolarHBondContact O-NH2 3.5Å; M250-R255 HydrophobicContact SD-CB 4.3Å; M250-R255 HydrophobicContact SD-CG 4.45Å; M250-D330 WeakPolarHBondContact CA-OD2 3.29Å; M250-D330 HydrophobicContact SD-CB 4.13Å; M250-C331 HydrophobicContact CE-CB 3.88Å; M250-C331 HydrophobicContact SD-CB 4.01Å; M250-P374 HydrophobicContact CE-CG 4.09Å; M250-L496 HydrophobicContact CE-CD1 3.37Å; M250-F497 WeakPolarHBondContact CG-O 3.44Å; M250-F498 HydrophobicContact CE-CD1 4.11Å; M250-F498 HydrophobicContact CE-CE1 3.82Å; M250-F498 HydrophobicContact CG-CD1 4.22Å; M250-F498 HydrophobicContact SD-CD1 4.04Å; M250-F498 HydrophobicContact SD-CE1 4.17Å; M250-P499 HydrophobicContact CB-CG 4.36Å; M250-P499 HydrophobicContact CG-CG 4.48Å
251K94.8Very high85.6Confident166 Ų16669 Ų6972%0.72235%0.353SS*.  trans-117.6-29.2-169.8-67.4-175.8178.6179.50114.1Q249 R255 D330Q249-K251 HydrophobicContact CG-CB 4.26Å; Q249-K251 HydrophobicContact CG-CD 4.38Å; Q249-K251 HydrophobicContact CG-CG 4.2Å; K251-R255 PolarHBondContact O-NH1 3.12Å; K251-D330 PolarHBondContact N-OD2 3.17Å
252N95.1Very high88.4Confident51 Ų5163 Ų6327%0.27331%0.311SS..  trans-63.8146.4178.2-77-47.5000112.1P254 R255 N328 D330N252-P254 CarbonylContact C-O 3.49Å; N252-P254 CarbonylContact O-C 3.54Å; N252-R255 WeakPolarHBondContact O-CA 3.35Å; N252-R255 VanDerWaalsContact O-CD 3.24Å; N252-R255 WeakPolarHBondContact O-CD 3.47Å; N252-R255 PolarHBondContact O-N 3.22Å; N252-R255 PolarHBondContact O-NH1 2.99Å; N252-N328 WeakPolarHBondContact CB-O 3.48Å; N252-N328 VanDerWaalsContact CG-O 3.26Å; N252-N328 PolarHBondContact ND2-O 3Å; N252-D330 WeakPolarHBondContact CB-OD2 3.34Å; N252-D330 PolarHBondContact N-OD2 2.91Å; N252-D330 VanDerWaalsContact ND2-CG 3.32Å; N252-D330 PolarHBondContact ND2-OD1 3.44Å; N252-D330 PolarHBondContact ND2-OD2 2.79Å
253K93.6Very high91.1Very high132 Ų13254.6 Ų54.657%0.57428%0.279SS*.SBendtrans-132.3114.3172.9-63.9-164.9-173.8-163.30108.2H300K253-H300 WeakPolarHBondContact CE-CD2 3.35Å; K253-H300 PolarHBondContact NZ-CD2 3.37Å; K253-H300 PolarHBondContact NZ-NE2 3.1Å
254P95.9Very high93.8Very high51 Ų5151.3 Ų51.333%0.33126%0.256SS..SBendcis-65146.9-0.429-36000113.1N252 G256 H300 E302 K329N252-P254 CarbonylContact C-O 3.49Å; N252-P254 CarbonylContact O-C 3.54Å; P254-G256 VanDerWaalsContact C-N 3.27Å; P254-G256 PolarHBondContact O-N 3.22Å; P254-H300 CarbonylContact C-O 3.56Å; P254-H300 WeakPolarHBondContact CA-O 3.31Å; P254-E302 HydrophobicContact CB-CB 3.9Å; P254-E302 HydrophobicContact CG-CB 4.29Å; P254-K329 HydrophobicContact CG-CD 4.22Å
255R97.2Very high95.7Very high11 Ų1148.9 Ų48.94%0.04223%0.234CC..  trans-63.3-34.6179.7-65.7-79-170.9-118.19112.5M250 K251 N252 L299 H300 F301 D330 C331 P499M250-R255 PolarHBondContact O-NE 2.64Å; M250-R255 PolarHBondContact O-NH1 2.9Å; M250-R255 PolarHBondContact O-NH2 3.5Å; M250-R255 HydrophobicContact SD-CB 4.3Å; M250-R255 HydrophobicContact SD-CG 4.45Å; K251-R255 PolarHBondContact O-NH1 3.12Å; N252-R255 WeakPolarHBondContact O-CA 3.35Å; N252-R255 VanDerWaalsContact O-CD 3.24Å; N252-R255 WeakPolarHBondContact O-CD 3.47Å; N252-R255 PolarHBondContact O-N 3.22Å; N252-R255 PolarHBondContact O-NH1 2.99Å; R255-L299 WeakPolarHBondContact CG-O 3.43Å; R255-H300 HydrophobicContact CG-CB 3.88Å; R255-H300 PolarHBondContact N-O 2.86Å; R255-F301 HydrophobicContact CB-CD1 4.19Å; R255-F301 HydrophobicContact CB-CD2 4.15Å; R255-F301 HydrophobicContact CB-CE1 3.97Å; R255-F301 HydrophobicContact CB-CE2 3.92Å; R255-F301 HydrophobicContact CB-CG 4.27Å; R255-F301 HydrophobicContact CB-CZ 3.82Å; R255-F301 HydrophobicContact CG-CE2 4.32Å; R255-D330 PolarHBondContact O-N 3.46Å; R255-C331 PolarHBondContact O-N 2.89Å; R255-C331 VanDerWaalsContact O-N 3.08Å; R255-P499 PolarHBondContact NH2-O 3.04Å
256G98.2Very high96.7Very high0 Ų044.2 Ų44.20%021%0.21CC..EExtended strand (participates in β ladder)trans-177.2173.3-167.100000111.3P254 E302 C331P254-G256 VanDerWaalsContact C-N 3.27Å; P254-G256 PolarHBondContact O-N 3.22Å; G256-E302 WeakPolarHBondContact O-CB 3.46Å; G256-E302 PolarHBondContact O-N 3.12Å; G256-C331 WeakPolarHBondContact CA-O 3.5Å
257Y98.5Very high96.9Very high46 Ų4637.9 Ų37.918%0.1819%0.186CC..EExtended strand (participates in β ladder)trans-81.7141.6156.4-67.9-76.6000109E302 V304 Y321 H326 K329 I333Y257-E302 HydrophobicContact CD1-CB 4.25Å; Y257-E302 HydrophobicContact CD1-CG 4.18Å; Y257-E302 HydrophobicContact CE1-CG 4.17Å; Y257-E302 VanDerWaalsContact CE1-OE1 3.3Å; Y257-E302 WeakPolarHBondContact CE1-OE1 3.46Å; Y257-E302 WeakPolarHBondContact CE1-OE2 3.2Å; Y257-V304 HydrophobicContact CD1-CG2 4.22Å; Y257-Y321 AromaticContact CD1-CE1 3.71Å; Y257-Y321 HydrophobicContact CD1-CE1 3.71Å; Y257-Y321 HydrophobicContact CD2-CD1 4.14Å; Y257-Y321 HydrophobicContact CD2-CE1 4.08Å; Y257-Y321 AromaticContact CE1-CE1 3.9Å; Y257-Y321 HydrophobicContact CE1-CE1 3.9Å; Y257-Y321 HydrophobicContact CE2-CD1 4.46Å; Y257-Y321 HydrophobicContact CE2-CE1 4.26Å; Y257-Y321 HydrophobicContact CG-CD1 4.16Å; Y257-Y321 AromaticContact CG-CE1 3.8Å; Y257-Y321 HydrophobicContact CG-CE1 3.8Å; Y257-H326 AromaticContact CD2-CE1 3.66Å; Y257-H326 AromaticContact CD2-ND1 3.7Å; Y257-K329 VanDerWaalsContact CE2-NZ 3.26Å; Y257-K329 VanDerWaalsContact CZ-NZ 3.29Å; Y257-I333 PolarHBondContact O-N 2.94Å
258C98.6Very high96.8Very high0 Ų039.4 Ų39.40%019%0.187CC..EExtended strand (participates in β ladder)trans-12098.9164.8-179.80000107.5F296 F301 E302 I303 V304 I333C258-F296 HydrophobicContact CB-CB 4.2Å; C258-F301 HydrophobicContact CB-CB 3.8Å; C258-F301 HydrophobicContact CB-CD1 4.31Å; C258-F301 HydrophobicContact CB-CG 4.29Å; C258-E302 PolarHBondContact N-O 3.47Å; C258-I303 HydrophobicContact CB-CD1 3.72Å; C258-V304 PolarHBondContact O-N 3.41Å; C258-I333 CarbonylContact C-O 3.59Å; C258-I333 WeakPolarHBondContact CA-O 3.48Å; C258-I333 HydrophobicContact CB-CB 4.2Å
259L98.8Very high96.6Very high0 Ų039 Ų390%019%0.185CC..EExtended strand (participates in β ladder)trans-78.6136.3176.4-49.8-172.2000109.1V304 I317 L318 Y321 F332 I333 C334 C335L259-V304 CarbonylContact C-O 3.59Å; L259-V304 VanDerWaalsContact CA-O 3.3Å; L259-V304 WeakPolarHBondContact CA-O 3.5Å; L259-V304 HydrophobicContact CD2-CB 4.08Å; L259-I317 HydrophobicContact CD1-CG2 4.4Å; L259-L318 HydrophobicContact CD1-CD2 3.9Å; L259-Y321 HydrophobicContact CD1-CD2 3.45Å; L259-Y321 VanDerWaalsContact CD1-CD2 3.45Å; L259-Y321 HydrophobicContact CD1-CE2 4.01Å; L259-Y321 HydrophobicContact CD1-CG 3.79Å; L259-Y321 HydrophobicContact CD2-CD1 4.12Å; L259-Y321 HydrophobicContact CD2-CD2 3.7Å; L259-Y321 HydrophobicContact CD2-CE1 3.87Å; L259-Y321 HydrophobicContact CD2-CE2 3.42Å; L259-Y321 VanDerWaalsContact CD2-CE2 3.42Å; L259-Y321 HydrophobicContact CD2-CG 4.06Å; L259-Y321 HydrophobicContact CG-CD2 4.23Å; L259-Y321 HydrophobicContact CG-CE2 4.38Å; L259-Y321 HydrophobicContact CG-CG 4.5Å; L259-F332 HydrophobicContact CD1-CE2 3.86Å; L259-F332 HydrophobicContact CD1-CZ 3.65Å; L259-F332 HydrophobicContact CG-CE2 3.95Å; L259-F332 HydrophobicContact CG-CZ 4.03Å; L259-I333 PolarHBondContact N-O 2.9Å; L259-C334 HydrophobicContact CB-CB 4.46Å; L259-C335 PolarHBondContact O-N 2.86Å
260I98.8Very high96.5Very high0 Ų036.4 Ų36.40%017%0.17CC..EExtended strand (participates in β ladder)trans-128.3105.2174.8-55.2173.5000108.4K289 L292 S293 I303 V304 S305 Y306 C335 L337I260-K289 HydrophobicContact CG2-CB 4.35Å; I260-K289 HydrophobicContact CG2-CG 4.17Å; I260-L292 HydrophobicContact CD1-CB 3.78Å; I260-L292 HydrophobicContact CG2-CD1 4.42Å; I260-S293 WeakPolarHBondContact CD1-OG 3.42Å; I260-I303 HydrophobicContact CD1-CG2 3.77Å; I260-V304 PolarHBondContact N-O 3.25Å; I260-S305 CarbonylContact O-C 3.47Å; I260-S305 VanDerWaalsContact O-CA 3.25Å; I260-S305 WeakPolarHBondContact O-CA 3.27Å; I260-Y306 PolarHBondContact O-N 2.96Å; I260-C335 WeakPolarHBondContact CA-O 3.31Å; I260-C335 HydrophobicContact CG1-CB 4.25Å; I260-L337 HydrophobicContact CG2-CD1 4.31Å
261I98.8Very high96.3Very high0 Ų042.9 Ų42.90%020%0.201CC..EExtended strand (participates in β ladder)trans-93.4113.7174.9-58.9-179.2000107.5C309 I314 C335 I336 L337I261-C309 HydrophobicContact CG2-CB 4.24Å; I261-I314 HydrophobicContact CD1-CB 4.44Å; I261-I314 HydrophobicContact CD1-CG1 4.24Å; I261-I314 HydrophobicContact CD1-CG2 3.87Å; I261-I314 HydrophobicContact CG2-CD1 4.14Å; I261-I314 HydrophobicContact CG2-CG1 3.99Å; I261-C335 PolarHBondContact N-O 3.38Å; I261-I336 HydrophobicContact CD1-CG1 4.44Å; I261-L337 PolarHBondContact O-N 3.44Å
262N98.6Very high96Very high1 Ų140.7 Ų40.71%0.00520%0.197CC..EExtended strand (participates in β ladder)trans-119.890.6-168.9178.554.7000110.8T285 D286 K289 Y306 D307 D308N262-T285 WeakPolarHBondContact OD1-CB 3.3Å; N262-T285 WeakPolarHBondContact OD1-CG2 3.4Å; N262-T285 PolarHBondContact OD1-O 3.18Å; N262-T285 PolarHBondContact OD1-OG1 3.09Å; N262-D286 PolarHBondContact ND2-OD1 3.35Å; N262-K289 HydrophobicContact CB-CB 4.38Å; N262-K289 HydrophobicContact CB-CD 3.9Å; N262-K289 WeakPolarHBondContact ND2-CD 3.36Å; N262-Y306 PolarHBondContact N-O 2.95Å; N262-D307 WeakPolarHBondContact CB-OD1 3.5Å; N262-D307 PolarHBondContact ND2-OD1 3.24Å; N262-D307 WeakPolarHBondContact O-CA 3.45Å; N262-D308 PolarHBondContact O-N 3.07Å
263N98.1Very high95.6Very high0 Ų040.7 Ų40.70%020%0.196CC..  trans-91.2110.2-179.5-70.54.2000109.9F266 R282 C309 L337 Y346 T348N263-F266 HydrophobicContact CB-CE2 4.03Å; N263-F266 HydrophobicContact CB-CZ 3.63Å; N263-R282 WeakPolarHBondContact O-CB 3.45Å; N263-R282 VanDerWaalsContact O-CD 3.31Å; N263-R282 WeakPolarHBondContact O-CD 3.45Å; N263-R282 PolarHBondContact O-NH1 2.79Å; N263-C309 PolarHBondContact ND2-O 3.28Å; N263-C309 PolarHBondContact OD1-N 2.93Å; N263-L337 PolarHBondContact N-O 3.3Å; N263-Y346 PolarHBondContact ND2-O 3.18Å; N263-T348 HydrophobicContact CB-CG2 3.94Å
264H97.2Very high95.2Very high49 Ų4939.1 Ų39.123%0.22720%0.198CC..  trans-98.8-57.3176.3172.2-88.6000112.1F266 D281 R282 T285 D308H264-F266 WeakPolarHBondContact O-CD2 3.49Å; H264-D281 CarbonylContact O-C 3.52Å; H264-D281 VanDerWaalsContact O-CA 3.24Å; H264-D281 WeakPolarHBondContact O-CA 3.41Å; H264-D281 WeakPolarHBondContact O-CB 3.47Å; H264-R282 PolarHBondContact O-N 3.04Å; H264-T285 HydrophobicContact CB-CG2 3.82Å; H264-D308 WeakPolarHBondContact CA-OD1 3.22Å; H264-D308 PolarHBondContact N-OD1 3.31Å
265D97.1Very high94.6Very high53 Ų5345.1 Ų45.128%0.28322%0.221SC..  trans-90.4129.2-173-175.122.2000112.5S267 R270 D308 T348D265-S267 VanDerWaalsContact CG-OG 3.23Å; D265-S267 VanDerWaalsContact OD1-CB 3.29Å; D265-S267 WeakPolarHBondContact OD1-CB 3.48Å; D265-S267 PolarHBondContact OD1-N 3.13Å; D265-S267 PolarHBondContact OD1-OG 2.96Å; D265-S267 WeakPolarHBondContact OD2-CB 3.32Å; D265-S267 PolarHBondContact OD2-OG 3.38Å; D265-R270 IonicContact OD1-NH2 3.55Å; D265-R270 PolarHBondContact OD1-NH2 3.42Å; D265-D308 PolarHBondContact N-OD1 3.19Å; D265-T348 VanDerWaalsContact O-CB 3.3Å; D265-T348 WeakPolarHBondContact O-CB 3.26Å; D265-T348 WeakPolarHBondContact O-CG2 3.43Å
266F95.8Very high94Very high0 Ų045.8 Ų45.80%023%0.226CC..  trans-120.831176.3-68.2-96.9000111N263 H264 A269 R270 M279 D281 R282 S338 H339 G347N263-F266 HydrophobicContact CB-CE2 4.03Å; N263-F266 HydrophobicContact CB-CZ 3.63Å; H264-F266 WeakPolarHBondContact O-CD2 3.49Å; F266-A269 HydrophobicContact CB-CB 4.13Å; F266-A269 HydrophobicContact CD1-CB 4.32Å; F266-A269 PolarHBondContact O-N 2.83Å; F266-R270 WeakPolarHBondContact O-CG 3.4Å; F266-R270 PolarHBondContact O-N 2.67Å; F266-R270 VanDerWaalsContact O-N 3.07Å; F266-M279 HydrophobicContact CB-CG 4.06Å; F266-M279 HydrophobicContact CB-SD 3.88Å; F266-M279 HydrophobicContact CD1-CG 4.42Å; F266-M279 HydrophobicContact CD1-SD 3.35Å; F266-M279 WeakPolarHBondContact CD1-SD 3.23Å; F266-M279 HydrophobicContact CE1-SD 4.06Å; F266-M279 HydrophobicContact CG-CG 4.21Å; F266-M279 HydrophobicContact CG-SD 3.72Å; F266-D281 PolarHBondContact N-OD1 3.48Å; F266-D281 VanDerWaalsContact N-OD1 3.15Å; F266-R282 HydrophobicContact CD2-CG 4.4Å; F266-R282 HydrophobicContact CE2-CG 3.78Å; F266-S338 WeakPolarHBondContact CZ-OG 3.46Å; F266-H339 AromaticContact CD1-CD2 3.99Å; F266-H339 AromaticContact CD2-CD2 3.68Å; F266-H339 AromaticContact CD2-NE2 3.97Å; F266-H339 HydrophobicContact CE1-CB 4.5Å; F266-H339 AromaticContact CE1-CD2 3.81Å; F266-H339 AromaticContact CE2-CD2 3.53Å; F266-H339 AromaticContact CG-CD2 3.92Å; F266-H339 HydrophobicContact CZ-CB 4.48Å; F266-H339 AromaticContact CZ-CD2 3.58Å; F266-G347 WeakPolarHBondContact CE1-O 3.44Å
267S94.9Very high93.4Very high31 Ų3153.6 Ų53.622%0.21726%0.255CS..Hα-helixtrans-51.7-56.7173.252.30000112D265 A269 R270 E271D265-S267 VanDerWaalsContact CG-OG 3.23Å; D265-S267 VanDerWaalsContact OD1-CB 3.29Å; D265-S267 WeakPolarHBondContact OD1-CB 3.48Å; D265-S267 PolarHBondContact OD1-N 3.13Å; D265-S267 PolarHBondContact OD1-OG 2.96Å; D265-S267 WeakPolarHBondContact OD2-CB 3.32Å; D265-S267 PolarHBondContact OD2-OG 3.38Å; S267-A269 PolarHBondContact O-N 3.02Å; S267-R270 VanDerWaalsContact CA-NH2 3.34Å; S267-R270 WeakPolarHBondContact O-CB 3.17Å; S267-R270 PolarHBondContact O-N 3.31Å; S267-E271 WeakPolarHBondContact O-CG 3.35Å; S267-E271 PolarHBondContact O-N 3.09Å
268K93.6Very high92.6Very high103 Ų10360.7 Ų60.745%0.44829%0.287SS..Hα-helixtrans-53.5-50.7176.5-62.4176.5-177.1170.70111.8R270 E271 D272K268-R270 VanDerWaalsContact C-N 3.27Å; K268-R270 PolarHBondContact O-N 3.13Å; K268-E271 PolarHBondContact O-N 3.03Å; K268-D272 WeakPolarHBondContact O-CB 3.41Å; K268-D272 PolarHBondContact O-N 3.27Å
269A93Very high92.1Very high0 Ų062 Ų620%029%0.293CS..Hα-helixtrans-54.4-38.8176.200000113.7F266 S267 I273 L276 M279 T348 G350F266-A269 HydrophobicContact CB-CB 4.13Å; F266-A269 HydrophobicContact CD1-CB 4.32Å; F266-A269 PolarHBondContact O-N 2.83Å; S267-A269 PolarHBondContact O-N 3.02Å; A269-I273 WeakPolarHBondContact O-CB 3.23Å; A269-I273 PolarHBondContact O-N 2.83Å; A269-I273 VanDerWaalsContact O-N 3.16Å; A269-L276 HydrophobicContact CB-CD1 4.38Å; A269-M279 HydrophobicContact CB-SD 4.28Å; A269-T348 PolarHBondContact N-O 3.17Å; A269-T348 VanDerWaalsContact N-O 3.15Å; A269-G350 VanDerWaalsContact CB-CA 3.46Å
270R94.1Very high91.6Very high60 Ų6069.8 Ų69.823%0.22633%0.327CS..Hα-helixtrans-71.9-33.6176.8-72.4-176.9-71.7-90.94.8113.1D265 F266 S267 K268 R277 M279 D281D265-R270 IonicContact OD1-NH2 3.55Å; D265-R270 PolarHBondContact OD1-NH2 3.42Å; F266-R270 WeakPolarHBondContact O-CG 3.4Å; F266-R270 PolarHBondContact O-N 2.67Å; F266-R270 VanDerWaalsContact O-N 3.07Å; S267-R270 VanDerWaalsContact CA-NH2 3.34Å; S267-R270 WeakPolarHBondContact O-CB 3.17Å; S267-R270 PolarHBondContact O-N 3.31Å; K268-R270 VanDerWaalsContact C-N 3.27Å; K268-R270 PolarHBondContact O-N 3.13Å; R270-R277 VanDerWaalsContact O-CG 3.24Å; R270-R277 WeakPolarHBondContact O-CG 3.32Å; R270-M279 VanDerWaalsContact CD-O 3.3Å; R270-M279 WeakPolarHBondContact CD-O 3.32Å; R270-M279 WeakPolarHBondContact CG-O 3.41Å; R270-M279 PolarHBondContact NH1-O 3.43Å; R270-D281 IonicContact CZ-OD1 2.7Å; R270-D281 IonicContact NH1-OD1 3.43Å; R270-D281 PolarHBondContact NH1-OD1 3.03Å; R270-D281 IonicContact NH1-OD2 3.81Å; R270-D281 IonicContact NH2-OD1 3.31Å; R270-D281 PolarHBondContact NH2-OD1 3.36Å; R270-D281 IonicContact NH2-OD2 3.53Å; R270-D281 PolarHBondContact NH2-OD2 2.78Å
271E92.1Very high91.2Very high147 Ų14772 Ų7269%0.68734%0.339SS*.Hα-helixtrans-76.5-52.2-178.9-72.3173.7-164.300110.8S267 K268S267-E271 WeakPolarHBondContact O-CG 3.35Å; S267-E271 PolarHBondContact O-N 3.09Å; K268-E271 PolarHBondContact O-N 3.03Å
272D88.6Confident90.9Very high119 Ų11972.1 Ų72.164%0.63634%0.34SS*.Hα-helixtrans-80-34.9-172.2-65.2-29.2000113.3K268K268-D272 WeakPolarHBondContact O-CB 3.41Å; K268-D272 PolarHBondContact O-N 3.27Å
273I87Confident90.4Very high52 Ų5278.3 Ų78.327%0.26737%0.366SS..  trans-113.7104.7-172.2-55.3177.6000110.7A269 Q275 L276 R277 D349 G350A269-I273 WeakPolarHBondContact O-CB 3.23Å; A269-I273 PolarHBondContact O-N 2.83Å; A269-I273 VanDerWaalsContact O-N 3.16Å; I273-Q275 HydrophobicContact CG2-CB 4.43Å; I273-Q275 PolarHBondContact O-N 3.29Å; I273-Q275 VanDerWaalsContact O-N 3.12Å; I273-L276 HydrophobicContact CB-CB 4.2Å; I273-L276 HydrophobicContact CB-CD1 4.19Å; I273-L276 HydrophobicContact CB-CG 4.19Å; I273-L276 HydrophobicContact CD1-CD1 4.07Å; I273-L276 HydrophobicContact CG2-CB 4.18Å; I273-L276 HydrophobicContact CG2-CD1 4.04Å; I273-L276 HydrophobicContact CG2-CG 3.76Å; I273-L276 PolarHBondContact O-N 2.94Å; I273-R277 PolarHBondContact O-N 3.15Å; I273-D349 WeakPolarHBondContact CD1-O 3.46Å; I273-G350 VanDerWaalsContact CD1-O 3.27Å; I273-G350 WeakPolarHBondContact CD1-O 3.43Å
274T83.8Confident90Very high98 Ų9878.7 Ų78.760%0.60137%0.37SS*.G310 helixtrans-54.8-34.9-176.753.10000114.1L276 R277T274-L276 VanDerWaalsContact C-N 3.33Å; T274-R277 WeakPolarHBondContact O-CG 3.45Å
275Q84.1Confident89.7Confident177 Ų17776.4 Ų76.483%0.82736%0.36SS*.G310 helixtrans-70.1-29.1177.7-55-167.631.700112.5I273I273-Q275 HydrophobicContact CG2-CB 4.43Å; I273-Q275 PolarHBondContact O-N 3.29Å; I273-Q275 VanDerWaalsContact O-N 3.12Å
276L84.7Confident89.6Confident26 Ų2677.7 Ų77.714%0.13637%0.366CS..G310 helixtrans-94.35.2-177.3-59.1-175.5000113.8A269 I273 T274 K278 M279 Y346 G350A269-L276 HydrophobicContact CB-CD1 4.38Å; I273-L276 HydrophobicContact CB-CB 4.2Å; I273-L276 HydrophobicContact CB-CD1 4.19Å; I273-L276 HydrophobicContact CB-CG 4.19Å; I273-L276 HydrophobicContact CD1-CD1 4.07Å; I273-L276 HydrophobicContact CG2-CB 4.18Å; I273-L276 HydrophobicContact CG2-CD1 4.04Å; I273-L276 HydrophobicContact CG2-CG 3.76Å; I273-L276 PolarHBondContact O-N 2.94Å; T274-L276 VanDerWaalsContact C-N 3.33Å; L276-K278 PolarHBondContact O-N 3.35Å; L276-M279 HydrophobicContact CB-CB 4.39Å; L276-M279 HydrophobicContact CD1-CE 4.26Å; L276-M279 HydrophobicContact CD2-CE 4.06Å; L276-M279 WeakPolarHBondContact O-CB 3.19Å; L276-M279 PolarHBondContact O-N 3Å; L276-Y346 HydrophobicContact CD1-CD1 4.29Å; L276-Y346 HydrophobicContact CD1-CE1 3.99Å; L276-G350 VanDerWaalsContact CD1-O 3.32Å; L276-G350 WeakPolarHBondContact CD1-O 3.37Å
277R86Confident89.6Confident163 Ų16379.9 Ų79.962%0.61538%0.381SS*.THydrogen-bonded Turntrans-50.8-22175.8-80.7177.6173.1-167.7-0.6115.8R270 I273 T274R270-R277 VanDerWaalsContact O-CG 3.24Å; R270-R277 WeakPolarHBondContact O-CG 3.32Å; I273-R277 PolarHBondContact O-N 3.15Å; T274-R277 WeakPolarHBondContact O-CG 3.45Å
278K81.8Confident89.6Confident195 Ų19578.4 Ų78.485%0.84837%0.371SS*.THydrogen-bonded Turntrans-95.7-2.2177.1-64.5-178.5-178.1174.50114L276 K280L276-K278 PolarHBondContact O-N 3.35Å; K278-K280 PolarHBondContact O-N 2.98Å
279M87Confident89.8Confident27 Ų2775.2 Ų75.213%0.13336%0.357CS..PPolyproline II helixtrans-65.8125.1177-175.2174.4-88.700110F266 A269 R270 L276 H339 Y346F266-M279 HydrophobicContact CB-CG 4.06Å; F266-M279 HydrophobicContact CB-SD 3.88Å; F266-M279 HydrophobicContact CD1-CG 4.42Å; F266-M279 HydrophobicContact CD1-SD 3.35Å; F266-M279 WeakPolarHBondContact CD1-SD 3.23Å; F266-M279 HydrophobicContact CE1-SD 4.06Å; F266-M279 HydrophobicContact CG-CG 4.21Å; F266-M279 HydrophobicContact CG-SD 3.72Å; A269-M279 HydrophobicContact CB-SD 4.28Å; R270-M279 VanDerWaalsContact CD-O 3.3Å; R270-M279 WeakPolarHBondContact CD-O 3.32Å; R270-M279 WeakPolarHBondContact CG-O 3.41Å; R270-M279 PolarHBondContact NH1-O 3.43Å; L276-M279 HydrophobicContact CB-CB 4.39Å; L276-M279 HydrophobicContact CD1-CE 4.26Å; L276-M279 HydrophobicContact CD2-CE 4.06Å; L276-M279 WeakPolarHBondContact O-CB 3.19Å; L276-M279 PolarHBondContact O-N 3Å; M279-H339 HydrophobicContact CE-CB 3.76Å; M279-H339 VanDerWaalsContact CG-CD2 3.5Å; M279-H339 WeakPolarHBondContact CG-CD2 3.46Å; M279-H339 HydrophobicContact SD-CB 4.43Å; M279-H339 VanDerWaalsContact SD-CD2 3.58Å; M279-Y346 HydrophobicContact CE-CD2 3.85Å; M279-Y346 HydrophobicContact CE-CE2 4.19Å; M279-Y346 HydrophobicContact CE-CG 4.05Å
280K87.9Confident90Very high165 Ų16582 Ų8272%0.71739%0.389SS*.PPolyproline II helixtrans-98.6149.2-176.1-60.8179.8-178176.50110.9K278 H339K278-K280 PolarHBondContact O-N 2.98Å; K280-H339 PolarHBondContact O-CE1 3.32Å; K280-H339 PolarHBondContact O-NE2 2.94Å
281D91.8Very high90.2Very high45 Ų4579.7 Ų79.724%0.24138%0.383CS..PPolyproline II helixtrans-61.5150.3173.5-48.1-42.3000111.7H264 F266 R270 K283H264-D281 CarbonylContact O-C 3.52Å; H264-D281 VanDerWaalsContact O-CA 3.24Å; H264-D281 WeakPolarHBondContact O-CA 3.41Å; H264-D281 WeakPolarHBondContact O-CB 3.47Å; F266-D281 PolarHBondContact N-OD1 3.48Å; F266-D281 VanDerWaalsContact N-OD1 3.15Å; R270-D281 IonicContact CZ-OD1 2.7Å; R270-D281 IonicContact NH1-OD1 3.43Å; R270-D281 PolarHBondContact NH1-OD1 3.03Å; R270-D281 IonicContact NH1-OD2 3.81Å; R270-D281 IonicContact NH2-OD1 3.31Å; R270-D281 PolarHBondContact NH2-OD1 3.36Å; R270-D281 IonicContact NH2-OD2 3.53Å; R270-D281 PolarHBondContact NH2-OD2 2.78Å; D281-K283 VanDerWaalsContact C-N 3.26Å; D281-K283 PolarHBondContact O-N 3.16Å; D281-K283 VanDerWaalsContact O-N 3.09Å
282R92.5Very high90.5Very high4 Ų472.7 Ų72.72%0.01535%0.35CS..  trans-88.945.1-170.3-64.6-178.460-86.90.4114N263 H264 F266 G284 T285 L337 S338 H339 R435N263-R282 WeakPolarHBondContact O-CB 3.45Å; N263-R282 VanDerWaalsContact O-CD 3.31Å; N263-R282 WeakPolarHBondContact O-CD 3.45Å; N263-R282 PolarHBondContact O-NH1 2.79Å; H264-R282 PolarHBondContact O-N 3.04Å; F266-R282 HydrophobicContact CD2-CG 4.4Å; F266-R282 HydrophobicContact CE2-CG 3.78Å; R282-G284 PolarHBondContact O-N 2.87Å; R282-T285 HydrophobicContact CB-CG2 4.22Å; R282-T285 PolarHBondContact NH1-OG1 2.89Å; R282-T285 WeakPolarHBondContact O-CB 3.33Å; R282-T285 VanDerWaalsContact O-CG2 3.24Å; R282-T285 WeakPolarHBondContact O-CG2 3.33Å; R282-T285 PolarHBondContact O-N 2.94Å; R282-L337 PolarHBondContact NH1-O 2.89Å; R282-S338 PolarHBondContact NE-O 3.22Å; R282-H339 WeakPolarHBondContact CG-NE2 3.5Å; R282-R435 VanDerWaalsContact C-NH1 3.34Å; R282-R435 VanDerWaalsContact CA-CZ 3.45Å
283K88.4Confident91Very high131 Ų13168.3 Ų68.357%0.5733%0.329SS*.THydrogen-bonded Turntrans-39.2128.8174.8-61.3-168.5176.8-168.20112.7D281 R435 P437D281-K283 VanDerWaalsContact C-N 3.26Å; D281-K283 PolarHBondContact O-N 3.16Å; D281-K283 VanDerWaalsContact O-N 3.09Å; K283-R435 WeakPolarHBondContact O-CD 3.44Å; K283-R435 PolarHBondContact O-NH1 2.84Å; K283-P437 HydrophobicContact CB-CB 4.31Å
284G88.8Confident91.5Very high8 Ų871.1 Ų71.18%0.08234%0.339CS..THydrogen-bonded Turntrans90.8-6.3-173.500000114.8R282 D286 C287R282-G284 PolarHBondContact O-N 2.87Å; G284-D286 PolarHBondContact O-N 2.99Å; G284-C287 WeakPolarHBondContact O-CB 3.42Å; G284-C287 PolarHBondContact O-N 3.09Å
285T91.4Very high92.2Very high0 Ų066.5 Ų66.50%031%0.311CS..Hα-helixtrans-64.8-28.1174.3-167.30000113.1N262 H264 R282 C287 D288 K289N262-T285 WeakPolarHBondContact OD1-CB 3.3Å; N262-T285 WeakPolarHBondContact OD1-CG2 3.4Å; N262-T285 PolarHBondContact OD1-O 3.18Å; N262-T285 PolarHBondContact OD1-OG1 3.09Å; H264-T285 HydrophobicContact CB-CG2 3.82Å; R282-T285 HydrophobicContact CB-CG2 4.22Å; R282-T285 PolarHBondContact NH1-OG1 2.89Å; R282-T285 WeakPolarHBondContact O-CB 3.33Å; R282-T285 VanDerWaalsContact O-CG2 3.24Å; R282-T285 WeakPolarHBondContact O-CG2 3.33Å; R282-T285 PolarHBondContact O-N 2.94Å; T285-C287 VanDerWaalsContact C-N 3.25Å; T285-C287 PolarHBondContact O-N 3.13Å; T285-D288 WeakPolarHBondContact O-CA 3.37Å; T285-D288 WeakPolarHBondContact O-CB 3.24Å; T285-D288 PolarHBondContact O-N 3.26Å; T285-K289 PolarHBondContact O-N 3.21Å
286D95.3Very high92.9Very high80 Ų8058 Ų5843%0.42827%0.271SS..Hα-helixtrans-67.9-29.3177.7-52.1-50.2000111.9N262 G284 D288 K289 E290N262-D286 PolarHBondContact ND2-OD1 3.35Å; G284-D286 PolarHBondContact O-N 2.99Å; D286-D288 VanDerWaalsContact C-N 3.32Å; D286-K289 PolarHBondContact O-N 3.16Å; D286-E290 WeakPolarHBondContact O-CB 3.44Å; D286-E290 PolarHBondContact O-N 3.29Å
287C94.4Very high93.5Very high46 Ų4664 Ų6431%0.31130%0.296SS..Hα-helixtrans-65.9-35.1171.4-51.40000111.7G284 T285 A291 V438 Q445G284-C287 WeakPolarHBondContact O-CB 3.42Å; G284-C287 PolarHBondContact O-N 3.09Å; T285-C287 VanDerWaalsContact C-N 3.25Å; T285-C287 PolarHBondContact O-N 3.13Å; C287-A291 VanDerWaalsContact O-CB 3.24Å; C287-A291 WeakPolarHBondContact O-CB 3.48Å; C287-A291 PolarHBondContact O-N 3.43Å; C287-V438 PolarHBondContact SG-O 2.76Å; C287-Q445 PolarHBondContact O-NE2 3.42Å
288D94.9Very high94Very high0 Ų060.6 Ų60.60%029%0.287CS..Hα-helixtrans-72.2-44.2173.8-72.5-18000111.3T285 D286 E290 A291 L292 L337 G440 T441 I444 Q445T285-D288 WeakPolarHBondContact O-CA 3.37Å; T285-D288 WeakPolarHBondContact O-CB 3.24Å; T285-D288 PolarHBondContact O-N 3.26Å; D286-D288 VanDerWaalsContact C-N 3.32Å; D288-E290 VanDerWaalsContact C-N 3.33Å; D288-E290 PolarHBondContact O-N 3.31Å; D288-A291 PolarHBondContact O-N 2.84Å; D288-L292 WeakPolarHBondContact O-CB 3.37Å; D288-L292 VanDerWaalsContact O-CG 3.27Å; D288-L292 WeakPolarHBondContact O-CG 3.33Å; D288-L292 PolarHBondContact O-N 3.09Å; D288-L337 HydrophobicContact CB-CD1 3.84Å; D288-G440 VanDerWaalsContact OD1-CA 3.27Å; D288-G440 WeakPolarHBondContact OD1-CA 3.29Å; D288-T441 VanDerWaalsContact CG-N 3.28Å; D288-T441 VanDerWaalsContact CG-OG1 3.3Å; D288-T441 PolarHBondContact OD1-N 2.89Å; D288-T441 WeakPolarHBondContact OD2-CB 3.43Å; D288-T441 WeakPolarHBondContact OD2-CG2 3.34Å; D288-T441 PolarHBondContact OD2-N 3.31Å; D288-T441 PolarHBondContact OD2-OG1 2.96Å; D288-I444 HydrophobicContact CB-CB 4.09Å; D288-I444 HydrophobicContact CB-CG1 4.42Å; D288-I444 HydrophobicContact CB-CG2 3.73Å; D288-Q445 PolarHBondContact OD1-NE2 3.43Å
289K98.2Very high94.7Very high36 Ų3651.7 Ų51.716%0.15725%0.249CC..Hα-helixtrans-56.9-45.8173.1170.6178.8171176.60111.3I260 N262 T285 D286 S293 S305 D307 L337I260-K289 HydrophobicContact CG2-CB 4.35Å; I260-K289 HydrophobicContact CG2-CG 4.17Å; N262-K289 HydrophobicContact CB-CB 4.38Å; N262-K289 HydrophobicContact CB-CD 3.9Å; N262-K289 WeakPolarHBondContact ND2-CD 3.36Å; T285-K289 PolarHBondContact O-N 3.21Å; D286-K289 PolarHBondContact O-N 3.16Å; K289-S293 WeakPolarHBondContact O-CB 3.31Å; K289-S293 PolarHBondContact O-N 2.93Å; K289-S293 PolarHBondContact O-OG 3.29Å; K289-S305 WeakPolarHBondContact CE-OG 3.32Å; K289-S305 PolarHBondContact NZ-OG 3.45Å; K289-D307 IonicContact NZ-OD1 2.8Å; K289-D307 PolarHBondContact NZ-OD1 3.44Å; K289-D307 IonicContact NZ-OD2 3.21Å; K289-D307 PolarHBondContact NZ-OD2 2.92Å; K289-L337 HydrophobicContact CB-CD1 4.27Å
290E98.1Very high95.2Very high142 Ų14253 Ų5366%0.66425%0.254SS*.Hα-helixtrans-66-45.3177.7-172.3179-178.600111.5D286 D288 L292 S293 K294D286-E290 WeakPolarHBondContact O-CB 3.44Å; D286-E290 PolarHBondContact O-N 3.29Å; D288-E290 VanDerWaalsContact C-N 3.33Å; D288-E290 PolarHBondContact O-N 3.31Å; E290-L292 PolarHBondContact O-N 2.95Å; E290-S293 PolarHBondContact O-N 3.08Å; E290-K294 WeakPolarHBondContact O-CB 3.48Å; E290-K294 PolarHBondContact O-N 2.9Å
291A98.1Very high95.7Very high12 Ų1245.6 Ų45.610%0.09922%0.222CC..Hα-helixtrans-60.1-44.6177.800000112.4C287 D288 T295 C448C287-A291 VanDerWaalsContact O-CB 3.24Å; C287-A291 WeakPolarHBondContact O-CB 3.48Å; C287-A291 PolarHBondContact O-N 3.43Å; D288-A291 PolarHBondContact O-N 2.84Å; A291-T295 VanDerWaalsContact O-CB 3.27Å; A291-T295 WeakPolarHBondContact O-CB 3.24Å; A291-T295 PolarHBondContact O-N 2.77Å; A291-T295 PolarHBondContact O-OG1 2.75Å; A291-C448 VanDerWaalsContact C-SG 3.52Å; A291-C448 HydrophobicContact CB-CB 4.12Å
292L98.5Very high96Very high0 Ų047 Ų470%023%0.227CC..Hα-helixtrans-64.5-48.1174.8-72.5166.2000111.5I260 D288 E290 K294 T295 F296 C335 L337 I444I260-L292 HydrophobicContact CD1-CB 3.78Å; I260-L292 HydrophobicContact CG2-CD1 4.42Å; D288-L292 WeakPolarHBondContact O-CB 3.37Å; D288-L292 VanDerWaalsContact O-CG 3.27Å; D288-L292 WeakPolarHBondContact O-CG 3.33Å; D288-L292 PolarHBondContact O-N 3.09Å; E290-L292 PolarHBondContact O-N 2.95Å; L292-K294 VanDerWaalsContact C-N 3.32Å; L292-K294 PolarHBondContact O-N 3.41Å; L292-T295 PolarHBondContact O-N 2.83Å; L292-F296 HydrophobicContact CB-CD2 4.49Å; L292-F296 HydrophobicContact CD2-CD2 4.17Å; L292-F296 HydrophobicContact CD2-CE2 3.69Å; L292-F296 WeakPolarHBondContact O-CD2 3.49Å; L292-F296 PolarHBondContact O-N 3.02Å; L292-C335 HydrophobicContact CD1-CB 3.93Å; L292-L337 HydrophobicContact CD1-CD1 4.14Å; L292-L337 HydrophobicContact CD1-CD2 3.95Å; L292-L337 HydrophobicContact CD1-CG 4.4Å; L292-I444 HydrophobicContact CD1-CD1 4.26Å; L292-I444 HydrophobicContact CD1-CG2 3.85Å; L292-I444 HydrophobicContact CD2-CD1 4.37Å; L292-I444 HydrophobicContact CD2-CG2 3.94Å; L292-I444 HydrophobicContact CG-CG2 3.59Å
293S98.4Very high96.3Very high28 Ų2849 Ų4920%0.19624%0.238CC..Hα-helixtrans-58.1-45.1179.6-62.40000111.3I260 K289 E290 K297I260-S293 WeakPolarHBondContact CD1-OG 3.42Å; K289-S293 WeakPolarHBondContact O-CB 3.31Å; K289-S293 PolarHBondContact O-N 2.93Å; K289-S293 PolarHBondContact O-OG 3.29Å; E290-S293 PolarHBondContact O-N 3.08Å; S293-K297 WeakPolarHBondContact O-CB 3.41Å; S293-K297 PolarHBondContact O-N 2.99Å; S293-K297 VanDerWaalsContact O-N 3.15Å
294K98.1Very high96.8Very high111 Ų11144.3 Ų44.348%0.48322%0.22SC..Hα-helixtrans-63.9-52.4176.4-179.7171.9177.3178.30111.2E290 L292 K297 E298E290-K294 WeakPolarHBondContact O-CB 3.48Å; E290-K294 PolarHBondContact O-N 2.9Å; L292-K294 VanDerWaalsContact C-N 3.32Å; L292-K294 PolarHBondContact O-N 3.41Å; K294-K297 PolarHBondContact O-N 2.99Å; K294-E298 WeakPolarHBondContact CE-OE1 3.44Å; K294-E298 VanDerWaalsContact CG-OE1 3.3Å; K294-E298 WeakPolarHBondContact CG-OE1 3.43Å; K294-E298 WeakPolarHBondContact O-CG 3.37Å; K294-E298 PolarHBondContact O-N 3.36Å
295T98.1Very high97.2Very high0 Ų046.3 Ų46.30%023%0.232CC..Hα-helixtrans-59.8-51.6-176.3-59.50000112.1A291 L292 K297 E298 L299 C448 L451 R452A291-T295 VanDerWaalsContact O-CB 3.27Å; A291-T295 WeakPolarHBondContact O-CB 3.24Å; A291-T295 PolarHBondContact O-N 2.77Å; A291-T295 PolarHBondContact O-OG1 2.75Å; L292-T295 PolarHBondContact O-N 2.83Å; T295-K297 VanDerWaalsContact C-N 3.33Å; T295-K297 PolarHBondContact O-N 3.01Å; T295-E298 WeakPolarHBondContact O-CB 3.37Å; T295-E298 PolarHBondContact O-N 2.94Å; T295-L299 HydrophobicContact CG2-CD1 4.35Å; T295-L299 WeakPolarHBondContact O-CG 3.25Å; T295-L299 PolarHBondContact O-N 3.42Å; T295-C448 WeakPolarHBondContact OG1-CB 3.34Å; T295-L451 HydrophobicContact CG2-CB 3.8Å; T295-L451 HydrophobicContact CG2-CD1 3.97Å; T295-R452 HydrophobicContact CG2-CG 3.85Å
296F98.1Very high97.6Very high0 Ų049.8 Ų49.80%025%0.246CC..Hα-helixtrans-73.6-24.6-177.8-73.3-63.6000113C258 L292 L299 H300 F301 I303 I333 F378 L451C258-F296 HydrophobicContact CB-CB 4.2Å; L292-F296 HydrophobicContact CB-CD2 4.49Å; L292-F296 HydrophobicContact CD2-CD2 4.17Å; L292-F296 HydrophobicContact CD2-CE2 3.69Å; L292-F296 WeakPolarHBondContact O-CD2 3.49Å; L292-F296 PolarHBondContact O-N 3.02Å; F296-L299 HydrophobicContact CD1-CD1 4.14Å; F296-L299 HydrophobicContact CE1-CD1 4.26Å; F296-L299 CarbonylContact O-C 3.6Å; F296-L299 VanDerWaalsContact O-C 3.31Å; F296-L299 PolarHBondContact O-N 3.45Å; F296-H300 PolarHBondContact O-N 3.34Å; F296-F301 HydrophobicContact CB-CB 4.17Å; F296-F301 HydrophobicContact CB-CD2 4.42Å; F296-F301 HydrophobicContact CB-CG 4.49Å; F296-F301 HydrophobicContact CD1-CD2 4.08Å; F296-F301 HydrophobicContact CD1-CE2 4.38Å; F296-F301 WeakPolarHBondContact O-CB 3.38Å; F296-F301 PolarHBondContact O-N 3.43Å; F296-I303 HydrophobicContact CB-CD1 3.58Å; F296-I333 HydrophobicContact CD1-CD1 3.65Å; F296-I333 HydrophobicContact CE1-CD1 3.46Å; F296-I333 VanDerWaalsContact CE1-CD1 3.46Å; F296-I333 HydrophobicContact CZ-CD1 4.16Å; F296-I333 HydrophobicContact CZ-CG2 4.46Å; F296-F378 HydrophobicContact CE1-CE2 4.46Å; F296-F378 HydrophobicContact CE2-CD2 4.4Å; F296-F378 HydrophobicContact CE2-CE2 4.31Å; F296-F378 HydrophobicContact CZ-CD2 4.15Å; F296-F378 AromaticContact CZ-CE2 3.62Å; F296-F378 HydrophobicContact CZ-CE2 3.62Å; F296-F378 HydrophobicContact CZ-CZ 4.49Å; F296-L451 HydrophobicContact CE1-CD1 4.05Å; F296-L451 HydrophobicContact CE2-CD1 4.39Å; F296-L451 HydrophobicContact CZ-CD1 3.66Å
297K97.8Very high97.7Very high151 Ų15149.9 Ų49.966%0.65725%0.247SC*.Hα-helixtrans-71-39.5171.4-175.2175.2-177.6176.30111.9S293 K294 T295 L299 H300 I303S293-K297 WeakPolarHBondContact O-CB 3.41Å; S293-K297 PolarHBondContact O-N 2.99Å; S293-K297 VanDerWaalsContact O-N 3.15Å; K294-K297 PolarHBondContact O-N 2.99Å; T295-K297 VanDerWaalsContact C-N 3.33Å; T295-K297 PolarHBondContact O-N 3.01Å; K297-L299 VanDerWaalsContact C-N 3.28Å; K297-L299 PolarHBondContact O-N 3.26Å; K297-H300 PolarHBondContact O-N 2.81Å; K297-I303 HydrophobicContact CB-CD1 4.44Å; K297-I303 HydrophobicContact CB-CG1 3.97Å
298E96.7Very high97.9Very high91 Ų9150.6 Ų50.643%0.42525%0.247SC..Hα-helixtrans-59.2-41.5169.7-73.7165.5-179.900110.2K294 T295 H300 R452K294-E298 WeakPolarHBondContact CE-OE1 3.44Å; K294-E298 VanDerWaalsContact CG-OE1 3.3Å; K294-E298 WeakPolarHBondContact CG-OE1 3.43Å; K294-E298 WeakPolarHBondContact O-CG 3.37Å; K294-E298 PolarHBondContact O-N 3.36Å; T295-E298 WeakPolarHBondContact O-CB 3.37Å; T295-E298 PolarHBondContact O-N 2.94Å; E298-H300 PolarHBondContact O-N 2.77Å; E298-H300 PolarHBondContact O-ND1 3.45Å; E298-R452 WeakPolarHBondContact OE2-CD 3.47Å
299L96.7Very high98.1Very high9 Ų950.9 Ų50.95%0.04725%0.249CC..THydrogen-bonded Turntrans-77.715.6171.8-58.5176.2000115R255 T295 F296 K297 F301 L451 C455 F498R255-L299 WeakPolarHBondContact CG-O 3.43Å; T295-L299 HydrophobicContact CG2-CD1 4.35Å; T295-L299 WeakPolarHBondContact O-CG 3.25Å; T295-L299 PolarHBondContact O-N 3.42Å; F296-L299 HydrophobicContact CD1-CD1 4.14Å; F296-L299 HydrophobicContact CE1-CD1 4.26Å; F296-L299 CarbonylContact O-C 3.6Å; F296-L299 VanDerWaalsContact O-C 3.31Å; F296-L299 PolarHBondContact O-N 3.45Å; K297-L299 VanDerWaalsContact C-N 3.28Å; K297-L299 PolarHBondContact O-N 3.26Å; L299-F301 HydrophobicContact CB-CD2 4.11Å; L299-F301 HydrophobicContact CB-CE2 4.27Å; L299-F301 WeakPolarHBondContact O-CD2 3.48Å; L299-F301 PolarHBondContact O-N 3.05Å; L299-L451 HydrophobicContact CD1-CD2 4.44Å; L299-C455 HydrophobicContact CD2-CB 3.86Å; L299-F498 HydrophobicContact CD1-CB 4.08Å; L299-F498 HydrophobicContact CD1-CD2 4.36Å; L299-F498 HydrophobicContact CD1-CG 4.34Å; L299-F498 HydrophobicContact CD2-CB 3.98Å; L299-F498 HydrophobicContact CG-CB 4.43Å
300H97.6Very high98.1Very high54 Ų5450.1 Ų50.125%0.2525%0.248CC..THydrogen-bonded Turntrans63.628.4173.6-53.3-28.4000117.2K253 P254 R255 F296 K297 E298 P500K253-H300 WeakPolarHBondContact CE-CD2 3.35Å; K253-H300 PolarHBondContact NZ-CD2 3.37Å; K253-H300 PolarHBondContact NZ-NE2 3.1Å; P254-H300 CarbonylContact C-O 3.56Å; P254-H300 WeakPolarHBondContact CA-O 3.31Å; R255-H300 HydrophobicContact CG-CB 3.88Å; R255-H300 PolarHBondContact N-O 2.86Å; F296-H300 PolarHBondContact O-N 3.34Å; K297-H300 PolarHBondContact O-N 2.81Å; E298-H300 PolarHBondContact O-N 2.77Å; E298-H300 PolarHBondContact O-ND1 3.45Å; H300-P500 PolarHBondContact NE2-OXT 2.98Å; H300-P500 VanDerWaalsContact NE2-OXT 3.09Å
301F98.2Very high98Very high9 Ų943.7 Ų43.74%0.03922%0.219CC..  trans-83.7151.9167.6-71.8-98.9000112R255 C258 F296 L299 I303 C331 I333 F498R255-F301 HydrophobicContact CB-CD1 4.19Å; R255-F301 HydrophobicContact CB-CD2 4.15Å; R255-F301 HydrophobicContact CB-CE1 3.97Å; R255-F301 HydrophobicContact CB-CE2 3.92Å; R255-F301 HydrophobicContact CB-CG 4.27Å; R255-F301 HydrophobicContact CB-CZ 3.82Å; R255-F301 HydrophobicContact CG-CE2 4.32Å; C258-F301 HydrophobicContact CB-CB 3.8Å; C258-F301 HydrophobicContact CB-CD1 4.31Å; C258-F301 HydrophobicContact CB-CG 4.29Å; F296-F301 HydrophobicContact CB-CB 4.17Å; F296-F301 HydrophobicContact CB-CD2 4.42Å; F296-F301 HydrophobicContact CB-CG 4.49Å; F296-F301 HydrophobicContact CD1-CD2 4.08Å; F296-F301 HydrophobicContact CD1-CE2 4.38Å; F296-F301 WeakPolarHBondContact O-CB 3.38Å; F296-F301 PolarHBondContact O-N 3.43Å; L299-F301 HydrophobicContact CB-CD2 4.11Å; L299-F301 HydrophobicContact CB-CE2 4.27Å; L299-F301 WeakPolarHBondContact O-CD2 3.48Å; L299-F301 PolarHBondContact O-N 3.05Å; F301-I303 HydrophobicContact CB-CD1 4.15Å; F301-I303 PolarHBondContact O-N 3.43Å; F301-C331 HydrophobicContact CE1-CB 3.82Å; F301-C331 HydrophobicContact CZ-CB 3.98Å; F301-I333 HydrophobicContact CD1-CD1 3.94Å; F301-I333 HydrophobicContact CD1-CG1 4.13Å; F301-I333 HydrophobicContact CD2-CD1 4.35Å; F301-I333 HydrophobicContact CE1-CD1 3.49Å; F301-I333 VanDerWaalsContact CE1-CD1 3.49Å; F301-I333 HydrophobicContact CE1-CG1 3.66Å; F301-I333 HydrophobicContact CE2-CD1 3.95Å; F301-I333 HydrophobicContact CG-CD1 4.36Å; F301-I333 HydrophobicContact CZ-CD1 3.5Å; F301-I333 HydrophobicContact CZ-CG1 4.12Å; F301-F498 AromaticContact CE2-CD1 3.94Å; F301-F498 HydrophobicContact CE2-CD1 3.94Å; F301-F498 HydrophobicContact CE2-CE1 4.1Å; F301-F498 HydrophobicContact CZ-CD1 4.02Å; F301-F498 AromaticContact CZ-CE1 3.76Å; F301-F498 HydrophobicContact CZ-CE1 3.76Å
302E98.1Very high98Very high76 Ų7647.4 Ų47.436%0.35524%0.237SC..EExtended strand (participates in β ladder)trans-83.4105169.5-171.9178.1165.300108.4P254 G256 Y257 C258 K329P254-E302 HydrophobicContact CB-CB 3.9Å; P254-E302 HydrophobicContact CG-CB 4.29Å; G256-E302 WeakPolarHBondContact O-CB 3.46Å; G256-E302 PolarHBondContact O-N 3.12Å; Y257-E302 HydrophobicContact CD1-CB 4.25Å; Y257-E302 HydrophobicContact CD1-CG 4.18Å; Y257-E302 HydrophobicContact CE1-CG 4.17Å; Y257-E302 VanDerWaalsContact CE1-OE1 3.3Å; Y257-E302 WeakPolarHBondContact CE1-OE1 3.46Å; Y257-E302 WeakPolarHBondContact CE1-OE2 3.2Å; C258-E302 PolarHBondContact N-O 3.47Å; E302-K329 IonicContact OE2-NZ 2.68Å; E302-K329 PolarHBondContact OE2-NZ 3.38Å
303I98.4Very high98Very high46 Ų4651.2 Ų51.224%0.23626%0.255CS..EExtended strand (participates in β ladder)trans-80.1127.2-176.8-48.9-51.6000110C258 I260 F296 K297 F301C258-I303 HydrophobicContact CB-CD1 3.72Å; I260-I303 HydrophobicContact CD1-CG2 3.77Å; F296-I303 HydrophobicContact CB-CD1 3.58Å; K297-I303 HydrophobicContact CB-CD1 4.44Å; K297-I303 HydrophobicContact CB-CG1 3.97Å; F301-I303 HydrophobicContact CB-CD1 4.15Å; F301-I303 PolarHBondContact O-N 3.43Å
304V98.5Very high98Very high32 Ų3249.9 Ų49.919%0.19425%0.246CC..EExtended strand (participates in β ladder)trans-129.5120.7170.9-170.80000108.1Y257 C258 L259 I260 Y306Y257-V304 HydrophobicContact CD1-CG2 4.22Å; C258-V304 PolarHBondContact O-N 3.41Å; L259-V304 CarbonylContact C-O 3.59Å; L259-V304 VanDerWaalsContact CA-O 3.3Å; L259-V304 WeakPolarHBondContact CA-O 3.5Å; L259-V304 HydrophobicContact CD2-CB 4.08Å; I260-V304 PolarHBondContact N-O 3.25Å; V304-Y306 HydrophobicContact CB-CE2 4.45Å; V304-Y306 HydrophobicContact CG1-CD2 4.43Å; V304-Y306 HydrophobicContact CG1-CE2 3.59Å
305S98.2Very high97.9Very high49 Ų4946.6 Ų46.634%0.34323%0.232SC..EExtended strand (participates in β ladder)trans-116137.7-177.7670000112.1I260 K289I260-S305 CarbonylContact O-C 3.47Å; I260-S305 VanDerWaalsContact O-CA 3.25Å; I260-S305 WeakPolarHBondContact O-CA 3.27Å; K289-S305 WeakPolarHBondContact CE-OG 3.32Å; K289-S305 PolarHBondContact NZ-OG 3.45Å
306Y98.7Very high97.9Very high73 Ų7351.9 Ų51.929%0.28626%0.257SS..EExtended strand (participates in β ladder)trans-121.1133.3173.3-58.9-92.8000108.5I260 N262 V304 C309 I317 Y321I260-Y306 PolarHBondContact O-N 2.96Å; N262-Y306 PolarHBondContact N-O 2.95Å; V304-Y306 HydrophobicContact CB-CE2 4.45Å; V304-Y306 HydrophobicContact CG1-CD2 4.43Å; V304-Y306 HydrophobicContact CG1-CE2 3.59Å; Y306-C309 VanDerWaalsContact CB-SG 3.5Å; Y306-I317 HydrophobicContact CD1-CD1 3.57Å; Y306-I317 HydrophobicContact CD1-CG1 4.05Å; Y306-I317 HydrophobicContact CD2-CD1 3.99Å; Y306-I317 HydrophobicContact CD2-CG1 4.47Å; Y306-I317 HydrophobicContact CD2-CG2 3.97Å; Y306-I317 HydrophobicContact CE1-CD1 4.04Å; Y306-I317 HydrophobicContact CE1-CG1 3.98Å; Y306-I317 HydrophobicContact CE2-CD1 4.43Å; Y306-I317 HydrophobicContact CE2-CG1 4.42Å; Y306-I317 HydrophobicContact CE2-CG2 3.64Å; Y306-I317 HydrophobicContact CG-CD1 3.54Å; Y306-I317 HydrophobicContact CG-CG1 4.3Å; Y306-Y321 HydrophobicContact CE2-CE2 4.23Å; Y306-Y321 WeakPolarHBondContact OH-CE2 3.04Å
307D98.4Very high97.9Very high83 Ų8352.9 Ų52.944%0.44426%0.262SS..EExtended strand (participates in β ladder)trans-107.3145.6179.9-61.7-57.2000110.5N262 K289 C309N262-D307 WeakPolarHBondContact CB-OD1 3.5Å; N262-D307 PolarHBondContact ND2-OD1 3.24Å; N262-D307 WeakPolarHBondContact O-CA 3.45Å; K289-D307 IonicContact NZ-OD1 2.8Å; K289-D307 PolarHBondContact NZ-OD1 3.44Å; K289-D307 IonicContact NZ-OD2 3.21Å; K289-D307 PolarHBondContact NZ-OD2 2.92Å; D307-C309 PolarHBondContact O-N 3.5Å
308D98.2Very high97.9Very high60 Ų6045.7 Ų45.732%0.32123%0.231SC..SBendtrans54.237.9169.7-68.7-32.5000117N262 H264 D265 T348N262-D308 PolarHBondContact O-N 3.07Å; H264-D308 WeakPolarHBondContact CA-OD1 3.22Å; H264-D308 PolarHBondContact N-OD1 3.31Å; D265-D308 PolarHBondContact N-OD1 3.19Å; D308-T348 VanDerWaalsContact CA-CG2 3.49Å; D308-T348 HydrophobicContact CB-CG2 3.94Å; D308-T348 VanDerWaalsContact O-CG2 3.27Å; D308-T348 WeakPolarHBondContact O-CG2 3.46Å; D308-T348 PolarHBondContact O-OG1 3.44Å
309C98.4Very high98Very high6 Ų646.3 Ų46.34%0.04123%0.233CC..  trans-72.4132.7-178.3-50.50000113.7I261 N263 Y306 D307 E313 I314 G347 T348I261-C309 HydrophobicContact CG2-CB 4.24Å; N263-C309 PolarHBondContact ND2-O 3.28Å; N263-C309 PolarHBondContact OD1-N 2.93Å; Y306-C309 VanDerWaalsContact CB-SG 3.5Å; D307-C309 PolarHBondContact O-N 3.5Å; C309-E313 HydrophobicContact CB-CB 4.18Å; C309-I314 HydrophobicContact CB-CD1 4.37Å; C309-I314 HydrophobicContact CB-CG1 3.66Å; C309-G347 WeakPolarHBondContact O-CA 3.47Å; C309-T348 PolarHBondContact O-N 2.67Å; C309-T348 PolarHBondContact O-OG1 2.85Å
310T98.2Very high98Very high20 Ų2048 Ų4812%0.12325%0.254CS..  trans-66.4164.3164.262.80000111.3N312 E313 I314 T348 D349T310-N312 PolarHBondContact O-N 3.43Å; T310-E313 VanDerWaalsContact CB-OE2 3.27Å; T310-E313 WeakPolarHBondContact CB-OE2 3.32Å; T310-E313 VanDerWaalsContact CG2-OE2 3.3Å; T310-E313 WeakPolarHBondContact CG2-OE2 3.47Å; T310-E313 PolarHBondContact N-OE2 2.74Å; T310-E313 PolarHBondContact O-N 2.79Å; T310-E313 VanDerWaalsContact OG1-CD 3.23Å; T310-E313 WeakPolarHBondContact OG1-CG 3.34Å; T310-E313 PolarHBondContact OG1-N 2.79Å; T310-E313 PolarHBondContact OG1-OE2 3.04Å; T310-I314 WeakPolarHBondContact O-CG1 3.49Å; T310-I314 PolarHBondContact O-N 3.07Å; T310-I314 VanDerWaalsContact O-N 3.08Å; T310-T348 PolarHBondContact N-OG1 2.86Å; T310-D349 WeakPolarHBondContact CA-OD1 3.36Å; T310-D349 WeakPolarHBondContact CB-OD1 3.42Å; T310-D349 HydrophobicContact CG2-CB 3.82Å
311A96.6Very high98Very high7 Ų747 Ų476%0.05825%0.248CC..Hα-helixtrans-57.8-40.8-179.400000111.7I314 H315 D349 K351 A353A311-I314 WeakPolarHBondContact O-CB 3.24Å; A311-I314 PolarHBondContact O-N 2.86Å; A311-H315 PolarHBondContact O-CD2 3.33Å; A311-H315 VanDerWaalsContact O-CD2 3.24Å; A311-H315 PolarHBondContact O-N 3.38Å; A311-D349 PolarHBondContact N-OD1 2.64Å; A311-K351 HydrophobicContact CB-CB 3.78Å; A311-A353 HydrophobicContact CB-CB 4.43Å
312N97.6Very high97.9Very high91 Ų9148.6 Ų48.649%0.48726%0.255SS..Hα-helixtrans-65.9-44.8178.8-172.382.2000112.6T310 I314 H315 E316T310-N312 PolarHBondContact O-N 3.43Å; N312-I314 VanDerWaalsContact C-N 3.25Å; N312-I314 PolarHBondContact O-N 2.79Å; N312-H315 WeakPolarHBondContact O-CB 3.35Å; N312-H315 PolarHBondContact O-N 3.18Å; N312-H315 VanDerWaalsContact O-N 3.07Å; N312-E316 PolarHBondContact ND2-OE1 2.93Å; N312-E316 WeakPolarHBondContact O-CG 3.3Å; N312-E316 PolarHBondContact O-N 3.17Å
313E98.4Very high97.6Very high80 Ų8049.4 Ų49.437%0.37427%0.27SS..Hα-helixtrans-61.4-34.9176.7-71.5160.2143.800111.6C309 T310 E316 I317C309-E313 HydrophobicContact CB-CB 4.18Å; T310-E313 VanDerWaalsContact CB-OE2 3.27Å; T310-E313 WeakPolarHBondContact CB-OE2 3.32Å; T310-E313 VanDerWaalsContact CG2-OE2 3.3Å; T310-E313 WeakPolarHBondContact CG2-OE2 3.47Å; T310-E313 PolarHBondContact N-OE2 2.74Å; T310-E313 PolarHBondContact O-N 2.79Å; T310-E313 VanDerWaalsContact OG1-CD 3.23Å; T310-E313 WeakPolarHBondContact OG1-CG 3.34Å; T310-E313 PolarHBondContact OG1-N 2.79Å; T310-E313 PolarHBondContact OG1-OE2 3.04Å; E313-E316 PolarHBondContact O-N 2.95Å; E313-I317 WeakPolarHBondContact O-CB 3.29Å; E313-I317 VanDerWaalsContact O-CD1 3.3Å; E313-I317 WeakPolarHBondContact O-CD1 3.2Å; E313-I317 WeakPolarHBondContact O-CG1 3.15Å; E313-I317 PolarHBondContact O-N 3.48Å
314I98.3Very high97.3Very high0 Ų048.5 Ų48.50%027%0.269CS..Hα-helixtrans-60.6-46.1172.9-65.4171.8000110.6I261 C309 T310 A311 N312 I317 L318 L358I261-I314 HydrophobicContact CD1-CB 4.44Å; I261-I314 HydrophobicContact CD1-CG1 4.24Å; I261-I314 HydrophobicContact CD1-CG2 3.87Å; I261-I314 HydrophobicContact CG2-CD1 4.14Å; I261-I314 HydrophobicContact CG2-CG1 3.99Å; C309-I314 HydrophobicContact CB-CD1 4.37Å; C309-I314 HydrophobicContact CB-CG1 3.66Å; T310-I314 WeakPolarHBondContact O-CG1 3.49Å; T310-I314 PolarHBondContact O-N 3.07Å; T310-I314 VanDerWaalsContact O-N 3.08Å; A311-I314 WeakPolarHBondContact O-CB 3.24Å; A311-I314 PolarHBondContact O-N 2.86Å; N312-I314 VanDerWaalsContact C-N 3.25Å; N312-I314 PolarHBondContact O-N 2.79Å; I314-I317 PolarHBondContact O-N 3.44Å; I314-L318 WeakPolarHBondContact O-CG 3.42Å; I314-L318 PolarHBondContact O-N 2.98Å; I314-L318 VanDerWaalsContact O-N 3.12Å; I314-L358 HydrophobicContact CG2-CD1 4.02Å; I314-L358 HydrophobicContact CG2-CD2 3.69Å
315H97.3Very high96.8Very high42 Ų4251.4 Ų51.419%0.19428%0.283CS..Hα-helixtrans-62.3-46.4176.6-81.1-86000112A311 N312 I317 L318 E319 Y361A311-H315 PolarHBondContact O-CD2 3.33Å; A311-H315 VanDerWaalsContact O-CD2 3.24Å; A311-H315 PolarHBondContact O-N 3.38Å; N312-H315 WeakPolarHBondContact O-CB 3.35Å; N312-H315 PolarHBondContact O-N 3.18Å; N312-H315 VanDerWaalsContact O-N 3.07Å; H315-I317 PolarHBondContact O-N 3.42Å; H315-L318 PolarHBondContact O-N 3.44Å; H315-E319 WeakPolarHBondContact O-CB 3.46Å; H315-E319 PolarHBondContact O-N 3.24Å; H315-Y361 AromaticContact ND1-CE2 3.45Å; H315-Y361 WeakPolarHBondContact ND1-CE2 3.46Å; H315-Y361 AromaticContact ND1-CZ 3.59Å; H315-Y361 PolarHBondContact ND1-OH 2.76Å
316E98.1Very high96.6Very high110 Ų11049 Ų4951%0.51427%0.267SS..Hα-helixtrans-61.1-40.6178.1-70.4173.8172.900112.5N312 E313 G320N312-E316 PolarHBondContact ND2-OE1 2.93Å; N312-E316 WeakPolarHBondContact O-CG 3.3Å; N312-E316 PolarHBondContact O-N 3.17Å; E313-E316 PolarHBondContact O-N 2.95Å; E316-G320 PolarHBondContact O-N 2.85Å
317I98.4Very high96.2Very high22 Ų2252.2 Ų52.211%0.11328%0.282CS..Hα-helixtrans-60.9-48.8174.4-70.7159.9000110.3L259 Y306 E313 I314 H315 G320 Y321L259-I317 HydrophobicContact CD1-CG2 4.4Å; Y306-I317 HydrophobicContact CD1-CD1 3.57Å; Y306-I317 HydrophobicContact CD1-CG1 4.05Å; Y306-I317 HydrophobicContact CD2-CD1 3.99Å; Y306-I317 HydrophobicContact CD2-CG1 4.47Å; Y306-I317 HydrophobicContact CD2-CG2 3.97Å; Y306-I317 HydrophobicContact CE1-CD1 4.04Å; Y306-I317 HydrophobicContact CE1-CG1 3.98Å; Y306-I317 HydrophobicContact CE2-CD1 4.43Å; Y306-I317 HydrophobicContact CE2-CG1 4.42Å; Y306-I317 HydrophobicContact CE2-CG2 3.64Å; Y306-I317 HydrophobicContact CG-CD1 3.54Å; Y306-I317 HydrophobicContact CG-CG1 4.3Å; E313-I317 WeakPolarHBondContact O-CB 3.29Å; E313-I317 VanDerWaalsContact O-CD1 3.3Å; E313-I317 WeakPolarHBondContact O-CD1 3.2Å; E313-I317 WeakPolarHBondContact O-CG1 3.15Å; E313-I317 PolarHBondContact O-N 3.48Å; I314-I317 PolarHBondContact O-N 3.44Å; H315-I317 PolarHBondContact O-N 3.42Å; I317-G320 PolarHBondContact O-N 2.77Å; I317-Y321 HydrophobicContact CG2-CD2 4.15Å; I317-Y321 HydrophobicContact CG2-CE2 4.34Å; I317-Y321 VanDerWaalsContact O-CD2 3.31Å; I317-Y321 WeakPolarHBondContact O-CD2 3.47Å; I317-Y321 PolarHBondContact O-N 2.86Å; I317-Y321 VanDerWaalsContact O-N 3.1Å
318L97.9Very high96Very high0 Ų054.6 Ų54.60%030%0.295CS..Hα-helixtrans-68.5-36.9-178.1-64.4-169.1000112.7L259 I314 H315 Y321 Q322 L358 Y361 F362L259-L318 HydrophobicContact CD1-CD2 3.9Å; I314-L318 WeakPolarHBondContact O-CG 3.42Å; I314-L318 PolarHBondContact O-N 2.98Å; I314-L318 VanDerWaalsContact O-N 3.12Å; H315-L318 PolarHBondContact O-N 3.44Å; L318-Y321 CarbonylContact O-C 3.57Å; L318-Y321 PolarHBondContact O-N 3.15Å; L318-Q322 PolarHBondContact O-N 3.33Å; L318-L358 HydrophobicContact CD1-CB 3.74Å; L318-L358 HydrophobicContact CD1-CD2 3.73Å; L318-L358 HydrophobicContact CD1-CG 4.24Å; L318-L358 WeakPolarHBondContact CD1-O 3.38Å; L318-Y361 HydrophobicContact CB-CD2 4.13Å; L318-Y361 HydrophobicContact CB-CG 4.22Å; L318-Y361 HydrophobicContact CD1-CD2 4.47Å; L318-F362 HydrophobicContact CB-CE2 4.02Å; L318-F362 HydrophobicContact CB-CZ 4.21Å; L318-F362 HydrophobicContact CD1-CE2 4.31Å; L318-F362 HydrophobicContact CD2-CE2 4.02Å; L318-F362 HydrophobicContact CD2-CZ 4.13Å; L318-F362 HydrophobicContact CG-CE2 4.33Å; L318-F362 WeakPolarHBondContact O-CZ 3.16Å
319E96.9Very high96Very high103 Ų10352.6 Ų52.648%0.48128%0.283SS..Hα-helixtrans-64.2-39.5173.9-174170.8-138.600112.3H315 Y321 Q322 S323 Y361H315-E319 WeakPolarHBondContact O-CB 3.46Å; H315-E319 PolarHBondContact O-N 3.24Å; E319-Y321 VanDerWaalsContact C-N 3.32Å; E319-Y321 PolarHBondContact O-N 3.22Å; E319-Q322 WeakPolarHBondContact O-CB 3.3Å; E319-Q322 PolarHBondContact O-N 3.34Å; E319-S323 PolarHBondContact O-N 3.08Å; E319-S323 VanDerWaalsContact O-N 3.14Å; E319-S323 PolarHBondContact O-OG 3.49Å; E319-Y361 HydrophobicContact CB-CD1 4.17Å; E319-Y361 HydrophobicContact CB-CE1 3.78Å; E319-Y361 HydrophobicContact CG-CE1 4.28Å
320G97.8Very high95.9Very high46 Ų4652.6 Ų52.647%0.47428%0.283SS..Hα-helixtrans-59.6-41.4171.500000112.5E316 I317 S323 A324E316-G320 PolarHBondContact O-N 2.85Å; I317-G320 PolarHBondContact O-N 2.77Å; G320-S323 PolarHBondContact O-N 2.95Å; G320-A324 PolarHBondContact O-N 2.9Å
321Y97.8Very high95.9Very high32 Ų3251.6 Ų51.613%0.12528%0.277CS..Hα-helixtrans-79.4-25.8176.6-80.9-74.2000114.6Y257 L259 Y306 I317 L318 E319 S323 A324 H326Y257-Y321 AromaticContact CD1-CE1 3.71Å; Y257-Y321 HydrophobicContact CD1-CE1 3.71Å; Y257-Y321 HydrophobicContact CD2-CD1 4.14Å; Y257-Y321 HydrophobicContact CD2-CE1 4.08Å; Y257-Y321 AromaticContact CE1-CE1 3.9Å; Y257-Y321 HydrophobicContact CE1-CE1 3.9Å; Y257-Y321 HydrophobicContact CE2-CD1 4.46Å; Y257-Y321 HydrophobicContact CE2-CE1 4.26Å; Y257-Y321 HydrophobicContact CG-CD1 4.16Å; Y257-Y321 AromaticContact CG-CE1 3.8Å; Y257-Y321 HydrophobicContact CG-CE1 3.8Å; L259-Y321 HydrophobicContact CD1-CD2 3.45Å; L259-Y321 VanDerWaalsContact CD1-CD2 3.45Å; L259-Y321 HydrophobicContact CD1-CE2 4.01Å; L259-Y321 HydrophobicContact CD1-CG 3.79Å; L259-Y321 HydrophobicContact CD2-CD1 4.12Å; L259-Y321 HydrophobicContact CD2-CD2 3.7Å; L259-Y321 HydrophobicContact CD2-CE1 3.87Å; L259-Y321 HydrophobicContact CD2-CE2 3.42Å; L259-Y321 VanDerWaalsContact CD2-CE2 3.42Å; L259-Y321 HydrophobicContact CD2-CG 4.06Å; L259-Y321 HydrophobicContact CG-CD2 4.23Å; L259-Y321 HydrophobicContact CG-CE2 4.38Å; L259-Y321 HydrophobicContact CG-CG 4.5Å; Y306-Y321 HydrophobicContact CE2-CE2 4.23Å; Y306-Y321 WeakPolarHBondContact OH-CE2 3.04Å; I317-Y321 HydrophobicContact CG2-CD2 4.15Å; I317-Y321 HydrophobicContact CG2-CE2 4.34Å; I317-Y321 VanDerWaalsContact O-CD2 3.31Å; I317-Y321 WeakPolarHBondContact O-CD2 3.47Å; I317-Y321 PolarHBondContact O-N 2.86Å; I317-Y321 VanDerWaalsContact O-N 3.1Å; L318-Y321 CarbonylContact O-C 3.57Å; L318-Y321 PolarHBondContact O-N 3.15Å; E319-Y321 VanDerWaalsContact C-N 3.32Å; E319-Y321 PolarHBondContact O-N 3.22Å; Y321-S323 PolarHBondContact O-N 3.32Å; Y321-A324 PolarHBondContact O-N 2.89Å; Y321-H326 PolarHBondContact O-NE2 3.43Å
322Q94.9Very high96Very high42 Ų4251.3 Ų51.320%0.19627%0.274CS..Hα-helixtrans-56.5-46.4166169.9-165.2-15.900109.7L318 E319 A324 Y361 K366 C367L318-Q322 PolarHBondContact O-N 3.33Å; E319-Q322 WeakPolarHBondContact O-CB 3.3Å; E319-Q322 PolarHBondContact O-N 3.34Å; Q322-A324 PolarHBondContact O-N 2.89Å; Q322-Y361 VanDerWaalsContact CG-O 3.25Å; Q322-Y361 WeakPolarHBondContact CG-O 3.3Å; Q322-K366 HydrophobicContact CG-CB 4.41Å; Q322-K366 WeakPolarHBondContact CG-O 2.85Å; Q322-K366 PolarHBondContact NE2-O 3.4Å; Q322-C367 HydrophobicContact CG-CB 4.23Å; Q322-C367 PolarHBondContact O-SG 2.9Å
323S91.9Very high96Very high94 Ų9447 Ų4766%0.65725%0.251SS*.THydrogen-bonded Turntrans-77-5.9-173.5-56.70000114.2E319 G320 Y321E319-S323 PolarHBondContact O-N 3.08Å; E319-S323 VanDerWaalsContact O-N 3.14Å; E319-S323 PolarHBondContact O-OG 3.49Å; G320-S323 PolarHBondContact O-N 2.95Å; Y321-S323 PolarHBondContact O-N 3.32Å
324A92.6Very high96Very high27 Ų2743.1 Ų43.122%0.22323%0.233CC..SBendtrans-77.8152.8-179.800000113G320 Y321 Q322 H326 S369G320-A324 PolarHBondContact O-N 2.9Å; Y321-A324 PolarHBondContact O-N 2.89Å; Q322-A324 PolarHBondContact O-N 2.89Å; A324-H326 PolarHBondContact O-CD2 2.92Å; A324-H326 PolarHBondContact O-N 3.29Å; A324-S369 PolarHBondContact O-OG 3.45Å
325D87.8Confident96.1Very high92 Ų9243.1 Ų43.149%0.49223%0.233SC..  trans-83101.5174.9-164.1-11.1000111.8K327D325-K327 WeakPolarHBondContact OD1-CB 3.35Å; D325-K327 WeakPolarHBondContact OD1-CD 3.38Å; D325-K327 WeakPolarHBondContact OD1-CG 3.33Å; D325-K327 PolarHBondContact OD1-N 2.94Å; D325-K327 IonicContact OD1-NZ 3.26Å; D325-K327 WeakPolarHBondContact OD2-CD 3.27Å; D325-K327 WeakPolarHBondContact OD2-CE 3.45Å; D325-K327 IonicContact OD2-NZ 3.6Å; D325-K327 PolarHBondContact OD2-NZ 2.94Å
326H94.9Very high96.1Very high0 Ų041.2 Ų41.20%022%0.224CC..  trans-88.78.1175-58.2-85.5000114.1Y257 Y321 A324 N328 K329 F332 S369 L370 K373Y257-H326 AromaticContact CD2-CE1 3.66Å; Y257-H326 AromaticContact CD2-ND1 3.7Å; Y321-H326 PolarHBondContact O-NE2 3.43Å; A324-H326 PolarHBondContact O-CD2 2.92Å; A324-H326 PolarHBondContact O-N 3.29Å; H326-N328 VanDerWaalsContact C-N 3.28Å; H326-N328 PolarHBondContact O-N 3.39Å; H326-K329 HydrophobicContact CB-CB 4.31Å; H326-K329 WeakPolarHBondContact O-CA 3.27Å; H326-K329 WeakPolarHBondContact O-CB 3.34Å; H326-K329 PolarHBondContact O-N 3.16Å; H326-F332 AromaticContact CE1-CD2 3.98Å; H326-S369 PolarHBondContact CD2-OG 2.72Å; H326-S369 PolarHBondContact N-OG 2.97Å; H326-L370 HydrophobicContact CB-CD2 3.48Å; H326-L370 VanDerWaalsContact CB-CD2 3.48Å; H326-L370 HydrophobicContact CB-CG 3.7Å; H326-K373 PolarHBondContact O-NZ 3.44Å
327K90.8Very high96.1Very high139 Ų13936 Ų3660%0.60420%0.2SC*.THydrogen-bonded Turntrans-51.6-45-177.2-79.3167.2-153.7140.80113.2D325 K329 K373D325-K327 WeakPolarHBondContact OD1-CB 3.35Å; D325-K327 WeakPolarHBondContact OD1-CD 3.38Å; D325-K327 WeakPolarHBondContact OD1-CG 3.33Å; D325-K327 PolarHBondContact OD1-N 2.94Å; D325-K327 IonicContact OD1-NZ 3.26Å; D325-K327 WeakPolarHBondContact OD2-CD 3.27Å; D325-K327 WeakPolarHBondContact OD2-CE 3.45Å; D325-K327 IonicContact OD2-NZ 3.6Å; D325-K327 PolarHBondContact OD2-NZ 2.94Å; K327-K329 VanDerWaalsContact C-N 3.28Å; K327-K329 PolarHBondContact O-N 2.77Å; K327-K373 PolarHBondContact O-NZ 3.44Å
328N93.8Very high95.9Very high134 Ų13435 Ų3572%0.71720%0.195SC*.THydrogen-bonded Turntrans-86.48.4179.5-61.3-25.9000113.7N252 H326N252-N328 WeakPolarHBondContact CB-O 3.48Å; N252-N328 VanDerWaalsContact CG-O 3.26Å; N252-N328 PolarHBondContact ND2-O 3Å; H326-N328 VanDerWaalsContact C-N 3.28Å; H326-N328 PolarHBondContact O-N 3.39Å
329K96.9Very high95.5Very high17 Ų1736.7 Ų36.77%0.07420%0.203CC..  trans-105.1148.3169.4-55.3-54.9-178.390.10108.8P254 Y257 E302 H326 K327 K373P254-K329 HydrophobicContact CG-CD 4.22Å; Y257-K329 VanDerWaalsContact CE2-NZ 3.26Å; Y257-K329 VanDerWaalsContact CZ-NZ 3.29Å; E302-K329 IonicContact OE2-NZ 2.68Å; E302-K329 PolarHBondContact OE2-NZ 3.38Å; H326-K329 HydrophobicContact CB-CB 4.31Å; H326-K329 WeakPolarHBondContact O-CA 3.27Å; H326-K329 WeakPolarHBondContact O-CB 3.34Å; H326-K329 PolarHBondContact O-N 3.16Å; K327-K329 VanDerWaalsContact C-N 3.28Å; K327-K329 PolarHBondContact O-N 2.77Å; K329-K373 WeakPolarHBondContact O-CD 3.45Å; K329-K373 WeakPolarHBondContact O-CE 3.11Å; K329-K373 PolarHBondContact O-NZ 3.14Å
330D97Very high94.8Very high6 Ų632.3 Ų32.33%0.03219%0.185CC..SBendtrans-98.7-21.3176.2-75.3-27.7000113.2Q249 M250 K251 N252 R255 P374Q249-D330 PolarHBondContact NE2-OD1 2.97Å; Q249-D330 WeakPolarHBondContact O-CB 3.48Å; M250-D330 WeakPolarHBondContact CA-OD2 3.29Å; M250-D330 HydrophobicContact SD-CB 4.13Å; K251-D330 PolarHBondContact N-OD2 3.17Å; N252-D330 WeakPolarHBondContact CB-OD2 3.34Å; N252-D330 PolarHBondContact N-OD2 2.91Å; N252-D330 VanDerWaalsContact ND2-CG 3.32Å; N252-D330 PolarHBondContact ND2-OD1 3.44Å; N252-D330 PolarHBondContact ND2-OD2 2.79Å; R255-D330 PolarHBondContact O-N 3.46Å; D330-P374 WeakPolarHBondContact O-CD 3.24Å
331C97.9Very high93.7Very high0 Ų033.3 Ų33.30%018%0.18CC..EExtended strand (participates in β ladder)trans-147.4157.6-173.7-176.50000111M250 R255 G256 F301 P374M250-C331 HydrophobicContact CE-CB 3.88Å; M250-C331 HydrophobicContact SD-CB 4.01Å; R255-C331 PolarHBondContact O-N 2.89Å; R255-C331 VanDerWaalsContact O-N 3.08Å; G256-C331 WeakPolarHBondContact CA-O 3.5Å; F301-C331 HydrophobicContact CE1-CB 3.82Å; F301-C331 HydrophobicContact CZ-CB 3.98Å; C331-P374 WeakPolarHBondContact CA-O 3.49Å; C331-P374 HydrophobicContact CB-CG 3.92Å; C331-P374 PolarHBondContact SG-O 2.87Å; C331-P374 VanDerWaalsContact SG-O 3.41Å
332F98.6Very high92.6Very high0 Ų037.5 Ų37.50%020%0.199CC..EExtended strand (participates in β ladder)trans-127135.4167.6174.8-98.5000109.8L259 H326 C334 F362 L370 P374 I376 F377L259-F332 HydrophobicContact CD1-CE2 3.86Å; L259-F332 HydrophobicContact CD1-CZ 3.65Å; L259-F332 HydrophobicContact CG-CE2 3.95Å; L259-F332 HydrophobicContact CG-CZ 4.03Å; H326-F332 AromaticContact CE1-CD2 3.98Å; F332-C334 HydrophobicContact CE1-CB 3.84Å; F332-C334 HydrophobicContact CZ-CB 4.08Å; F332-F362 HydrophobicContact CD1-CD1 4.13Å; F332-F362 HydrophobicContact CD1-CE1 4.28Å; F332-F362 HydrophobicContact CD1-CG 4.36Å; F332-F362 HydrophobicContact CD2-CE1 4.39Å; F332-F362 AromaticContact CE1-CD1 3.92Å; F332-F362 HydrophobicContact CE1-CD1 3.92Å; F332-F362 HydrophobicContact CE1-CD2 4.08Å; F332-F362 AromaticContact CE1-CE1 3.73Å; F332-F362 HydrophobicContact CE1-CE1 3.73Å; F332-F362 AromaticContact CE1-CE2 3.89Å; F332-F362 HydrophobicContact CE1-CE2 3.89Å; F332-F362 HydrophobicContact CE1-CG 4.09Å; F332-F362 AromaticContact CE1-CZ 3.71Å; F332-F362 HydrophobicContact CE1-CZ 3.71Å; F332-F362 AromaticContact CE2-CE1 3.86Å; F332-F362 HydrophobicContact CE2-CE1 3.86Å; F332-F362 HydrophobicContact CE2-CZ 4.14Å; F332-F362 HydrophobicContact CZ-CD1 4.14Å; F332-F362 AromaticContact CZ-CE1 3.48Å; F332-F362 HydrophobicContact CZ-CE1 3.48Å; F332-F362 VanDerWaalsContact CZ-CE1 3.48Å; F332-F362 AromaticContact CZ-CE2 3.99Å; F332-F362 HydrophobicContact CZ-CE2 3.99Å; F332-F362 AromaticContact CZ-CZ 3.39Å; F332-F362 HydrophobicContact CZ-CZ 3.39Å; F332-L370 HydrophobicContact CB-CD1 3.66Å; F332-L370 HydrophobicContact CB-CD2 3.91Å; F332-L370 HydrophobicContact CB-CG 4.47Å; F332-L370 HydrophobicContact CD2-CD1 4.42Å; F332-L370 HydrophobicContact CG-CD1 3.96Å; F332-P374 PolarHBondContact N-O 3.37Å; F332-I376 PolarHBondContact O-N 3.44Å; F332-F377 HydrophobicContact CE1-CE2 4.42Å; F332-F377 AromaticContact CE1-CZ 3.95Å; F332-F377 HydrophobicContact CE1-CZ 3.95Å
333I98.8Very high91.6Very high0 Ų037.1 Ų37.10%021%0.206CC..EExtended strand (participates in β ladder)trans-127.2135.3177-54.3-172.5000109.4Y257 C258 L259 F296 F301 I376 F378Y257-I333 PolarHBondContact O-N 2.94Å; C258-I333 CarbonylContact C-O 3.59Å; C258-I333 WeakPolarHBondContact CA-O 3.48Å; C258-I333 HydrophobicContact CB-CB 4.2Å; L259-I333 PolarHBondContact N-O 2.9Å; F296-I333 HydrophobicContact CD1-CD1 3.65Å; F296-I333 HydrophobicContact CE1-CD1 3.46Å; F296-I333 VanDerWaalsContact CE1-CD1 3.46Å; F296-I333 HydrophobicContact CZ-CD1 4.16Å; F296-I333 HydrophobicContact CZ-CG2 4.46Å; F301-I333 HydrophobicContact CD1-CD1 3.94Å; F301-I333 HydrophobicContact CD1-CG1 4.13Å; F301-I333 HydrophobicContact CD2-CD1 4.35Å; F301-I333 HydrophobicContact CE1-CD1 3.49Å; F301-I333 VanDerWaalsContact CE1-CD1 3.49Å; F301-I333 HydrophobicContact CE1-CG1 3.66Å; F301-I333 HydrophobicContact CE2-CD1 3.95Å; F301-I333 HydrophobicContact CG-CD1 4.36Å; F301-I333 HydrophobicContact CZ-CD1 3.5Å; F301-I333 HydrophobicContact CZ-CG1 4.12Å; I333-I376 CarbonylContact C-O 3.57Å; I333-I376 WeakPolarHBondContact CA-O 3.23Å; I333-I376 HydrophobicContact CD1-CD1 4.23Å; I333-I376 HydrophobicContact CG1-CB 4.18Å; I333-I376 HydrophobicContact CG1-CD1 4.12Å; I333-I376 HydrophobicContact CG1-CG1 4.43Å; I333-F378 HydrophobicContact CG2-CD2 4.02Å; I333-F378 HydrophobicContact CG2-CE2 4.13Å
334C98.7Very high91.2Very high0 Ų033.5 Ų33.50%018%0.18CC..EExtended strand (participates in β ladder)trans-130.6122.6170.6-177.40000110L259 F332 I376 F377 F378L259-C334 HydrophobicContact CB-CB 4.46Å; F332-C334 HydrophobicContact CE1-CB 3.84Å; F332-C334 HydrophobicContact CZ-CB 4.08Å; C334-I376 PolarHBondContact N-O 3.19Å; C334-F377 HydrophobicContact CB-CD1 3.72Å; C334-F377 HydrophobicContact CB-CE1 3.62Å; C334-F377 HydrophobicContact CB-CG 4.46Å; C334-F377 HydrophobicContact CB-CZ 4.28Å; C334-F377 CarbonylContact O-C 3.57Å; C334-F377 VanDerWaalsContact O-CA 3.27Å; C334-F377 WeakPolarHBondContact O-CA 3.31Å; C334-F378 PolarHBondContact O-N 3.12Å
335C98.6Very high91.1Very high0 Ų032.2 Ų32.20%017%0.169CC..EExtended strand (participates in β ladder)trans-109.4124.9177-60.40000108.6L259 I260 I261 L292 F378L259-C335 PolarHBondContact O-N 2.86Å; I260-C335 WeakPolarHBondContact CA-O 3.31Å; I260-C335 HydrophobicContact CG1-CB 4.25Å; I261-C335 PolarHBondContact N-O 3.38Å; L292-C335 HydrophobicContact CD1-CB 3.93Å; C335-F378 WeakPolarHBondContact CA-O 3.41Å
336I98.4Very high91.3Very high1 Ų129 Ų291%0.00515%0.15CC..EExtended strand (participates in β ladder)trans-118114.2178.3-54.8-176.3000109.2I261 V345 L358 F378 I379 Q380I261-I336 HydrophobicContact CD1-CG1 4.44Å; I336-V345 HydrophobicContact CG2-CB 4.37Å; I336-V345 HydrophobicContact CG2-CG1 4.22Å; I336-V345 HydrophobicContact CG2-CG2 4.25Å; I336-L358 HydrophobicContact CD1-CD1 3.8Å; I336-F378 PolarHBondContact N-O 3.13Å; I336-I379 HydrophobicContact CB-CD1 3.89Å; I336-I379 HydrophobicContact CD1-CD1 3.91Å; I336-I379 HydrophobicContact CG1-CD1 3.96Å; I336-Q380 PolarHBondContact O-N 3.27Å
337L97.4Very high91.4Very high0 Ų029 Ų290%015%0.15CC..EExtended strand (participates in β ladder)trans-10894.6179-47.8-178.9000108.3I260 I261 N263 R282 D288 K289 L292 Q380 I444I260-L337 HydrophobicContact CG2-CD1 4.31Å; I261-L337 PolarHBondContact O-N 3.44Å; N263-L337 PolarHBondContact N-O 3.3Å; R282-L337 PolarHBondContact NH1-O 2.89Å; D288-L337 HydrophobicContact CB-CD1 3.84Å; K289-L337 HydrophobicContact CB-CD1 4.27Å; L292-L337 HydrophobicContact CD1-CD1 4.14Å; L292-L337 HydrophobicContact CD1-CD2 3.95Å; L292-L337 HydrophobicContact CD1-CG 4.4Å; L337-Q380 HydrophobicContact CD2-CB 3.74Å; L337-Q380 HydrophobicContact CD2-CG 4.21Å; L337-I444 HydrophobicContact CD2-CD1 4.07Å; L337-I444 HydrophobicContact CD2-CG1 3.93Å
338S94.8Very high91.7Very high2 Ų222.7 Ų22.71%0.01412%0.123CC..SBendtrans-145.3-176.5-178.1-161.80000112.9F266 R282 Y346 Q380F266-S338 WeakPolarHBondContact CZ-OG 3.46Å; R282-S338 PolarHBondContact NE-O 3.22Å; S338-Y346 PolarHBondContact OG-O 3.27Å; S338-Q380 PolarHBondContact N-O 3.35Å; S338-Q380 VanDerWaalsContact O-O 3.05Å
339H88.5Confident91.9Very high35 Ų3516.9 Ų16.916%0.1629%0.092CC..  trans-76.7165.4155.5-69.5-65000108.9F266 M279 K280 R282 V345 Y346F266-H339 AromaticContact CD1-CD2 3.99Å; F266-H339 AromaticContact CD2-CD2 3.68Å; F266-H339 AromaticContact CD2-NE2 3.97Å; F266-H339 HydrophobicContact CE1-CB 4.5Å; F266-H339 AromaticContact CE1-CD2 3.81Å; F266-H339 AromaticContact CE2-CD2 3.53Å; F266-H339 AromaticContact CG-CD2 3.92Å; F266-H339 HydrophobicContact CZ-CB 4.48Å; F266-H339 AromaticContact CZ-CD2 3.58Å; M279-H339 HydrophobicContact CE-CB 3.76Å; M279-H339 VanDerWaalsContact CG-CD2 3.5Å; M279-H339 WeakPolarHBondContact CG-CD2 3.46Å; M279-H339 HydrophobicContact SD-CB 4.43Å; M279-H339 VanDerWaalsContact SD-CD2 3.58Å; K280-H339 PolarHBondContact O-CE1 3.32Å; K280-H339 PolarHBondContact O-NE2 2.94Å; R282-H339 WeakPolarHBondContact CG-NE2 3.5Å; H339-V345 WeakPolarHBondContact O-CA 3.46Å; H339-Y346 HydrophobicContact CB-CD2 4Å; H339-Y346 PolarHBondContact O-N 3.44Å
340G84Confident91.6Very high11 Ų1116.3 Ų16.311%0.1139%0.091CC..EExtended strand (participates in β ladder)trans-165.1170.3174.600000111V344 C382G340-V344 VanDerWaalsContact CA-O 3.23Å; G340-V344 WeakPolarHBondContact CA-O 3.31Å; G340-C382 CarbonylContact C-O 3.51Å; G340-C382 WeakPolarHBondContact CA-O 3.31Å
341D74.1Confident91.4Very high67 Ų6722 Ų2236%0.35812%0.115SC..EExtended strand (participates in β ladder)trans-133.1-174.8166.9-150.7-33.6000107.7G343 V344 Y346 C382 Q383 G384D341-G343 PolarHBondContact O-N 3.36Å; D341-V344 HydrophobicContact CB-CG2 3.91Å; D341-V344 PolarHBondContact N-O 3.47Å; D341-V344 PolarHBondContact O-N 2.76Å; D341-Y346 HydrophobicContact CB-CE2 4.31Å; D341-C382 PolarHBondContact N-O 2.92Å; D341-Q383 PolarHBondContact O-NE2 2.91Å; D341-G384 WeakPolarHBondContact OD1-CA 3.37Å
342K73.5Confident91Very high121 Ų12127.5 Ų27.553%0.52614%0.141SC..THydrogen-bonded Turntrans-53.6103.7-173.7-176.1-166.6167.4-144.90112.9Q383K342-Q383 WeakPolarHBondContact CA-O 3.47Å; K342-Q383 WeakPolarHBondContact CB-O 3.15Å; K342-Q383 PolarHBondContact N-O 3.03Å
343G73.9Confident90.5Very high33 Ų3327.5 Ų27.534%0.3414%0.141SC..THydrogen-bonded Turntrans86.9-1.1178.500000115.5D341 I355D341-G343 PolarHBondContact O-N 3.36Å; G343-I355 WeakPolarHBondContact O-CG1 3.42Å; G343-I355 PolarHBondContact O-N 2.91Å
344V84.4Confident90Very high19 Ų1929.1 Ų29.112%0.11515%0.152CC..EExtended strand (participates in β ladder)trans-130.9154.1-173.2-58.30000112.4G340 D341 E352 A353G340-V344 VanDerWaalsContact CA-O 3.23Å; G340-V344 WeakPolarHBondContact CA-O 3.31Å; D341-V344 HydrophobicContact CB-CG2 3.91Å; D341-V344 PolarHBondContact N-O 3.47Å; D341-V344 PolarHBondContact O-N 2.76Å; V344-E352 HydrophobicContact CB-CB 4.07Å; V344-E352 HydrophobicContact CB-CG 4.33Å; V344-E352 HydrophobicContact CG1-CB 4.17Å; V344-E352 HydrophobicContact CG2-CB 4.27Å; V344-E352 HydrophobicContact CG2-CG 3.96Å; V344-A353 WeakPolarHBondContact CA-O 3.32Å
345V91.1Very high89.4Confident0 Ų029.6 Ų29.60%016%0.155CC..EExtended strand (participates in β ladder)trans-114.6150.1164.2-64.40000109.2I336 H339 A353 I355 L358 I379 A381I336-V345 HydrophobicContact CG2-CB 4.37Å; I336-V345 HydrophobicContact CG2-CG1 4.22Å; I336-V345 HydrophobicContact CG2-CG2 4.25Å; H339-V345 WeakPolarHBondContact O-CA 3.46Å; V345-A353 HydrophobicContact CG2-CB 4.12Å; V345-A353 PolarHBondContact N-O 3.16Å; V345-A353 PolarHBondContact O-N 2.94Å; V345-I355 HydrophobicContact CG1-CD1 4.25Å; V345-I355 HydrophobicContact CG1-CG1 4.07Å; V345-L358 HydrophobicContact CG2-CD1 3.67Å; V345-I379 HydrophobicContact CG1-CG2 3.79Å; V345-A381 HydrophobicContact CG1-CB 3.94Å
346Y92.1Very high88.5Confident25 Ų2536.2 Ų36.210%0.09818%0.181CC..EExtended strand (participates in β ladder)trans-92.4139177.8-75.9-77.7000111.8N263 L276 M279 S338 H339 D341 G350 K351 E352N263-Y346 PolarHBondContact ND2-O 3.18Å; L276-Y346 HydrophobicContact CD1-CD1 4.29Å; L276-Y346 HydrophobicContact CD1-CE1 3.99Å; M279-Y346 HydrophobicContact CE-CD2 3.85Å; M279-Y346 HydrophobicContact CE-CE2 4.19Å; M279-Y346 HydrophobicContact CE-CG 4.05Å; S338-Y346 PolarHBondContact OG-O 3.27Å; H339-Y346 HydrophobicContact CB-CD2 4Å; H339-Y346 PolarHBondContact O-N 3.44Å; D341-Y346 HydrophobicContact CB-CE2 4.31Å; Y346-G350 VanDerWaalsContact CD1-O 3.25Å; Y346-G350 WeakPolarHBondContact CD1-O 3.38Å; Y346-G350 WeakPolarHBondContact CE1-O 3.23Å; Y346-K351 WeakPolarHBondContact CA-O 3.43Å; Y346-E352 HydrophobicContact CD1-CG 4.08Å; Y346-E352 HydrophobicContact CE1-CG 3.55Å; Y346-E352 PolarHBondContact OH-OE1 3.09Å
347G97Very high87.8Confident0 Ų039.5 Ų39.50%020%0.199CC..  trans-71.9167158.100000111.9F266 C309 D349 G350 K351F266-G347 WeakPolarHBondContact CE1-O 3.44Å; C309-G347 WeakPolarHBondContact O-CA 3.47Å; G347-D349 PolarHBondContact O-N 3.09Å; G347-G350 WeakPolarHBondContact O-CA 3.42Å; G347-G350 PolarHBondContact O-N 3.45Å; G347-K351 PolarHBondContact N-O 2.87Å
348T97.3Very high87.5Confident5 Ų539.6 Ų39.63%0.03120%0.199CC..THydrogen-bonded Turntrans-66.2-20173.254.40000113.7N263 D265 A269 D308 C309 T310 G350N263-T348 HydrophobicContact CB-CG2 3.94Å; D265-T348 VanDerWaalsContact O-CB 3.3Å; D265-T348 WeakPolarHBondContact O-CB 3.26Å; D265-T348 WeakPolarHBondContact O-CG2 3.43Å; A269-T348 PolarHBondContact N-O 3.17Å; A269-T348 VanDerWaalsContact N-O 3.15Å; D308-T348 VanDerWaalsContact CA-CG2 3.49Å; D308-T348 HydrophobicContact CB-CG2 3.94Å; D308-T348 VanDerWaalsContact O-CG2 3.27Å; D308-T348 WeakPolarHBondContact O-CG2 3.46Å; D308-T348 PolarHBondContact O-OG1 3.44Å; C309-T348 PolarHBondContact O-N 2.67Å; C309-T348 PolarHBondContact O-OG1 2.85Å; T310-T348 PolarHBondContact N-OG1 2.86Å; T348-G350 PolarHBondContact O-N 3.46Å
349D96Very high87.1Confident13 Ų1340.6 Ų40.67%0.0721%0.205CC..THydrogen-bonded Turntrans-76-2.2166.764.9-28000113.6I273 T310 A311 G347 K351I273-D349 WeakPolarHBondContact CD1-O 3.46Å; T310-D349 WeakPolarHBondContact CA-OD1 3.36Å; T310-D349 WeakPolarHBondContact CB-OD1 3.42Å; T310-D349 HydrophobicContact CG2-CB 3.82Å; A311-D349 PolarHBondContact N-OD1 2.64Å; G347-D349 PolarHBondContact O-N 3.09Å; D349-K351 PolarHBondContact O-N 2.76Å; D349-K351 VanDerWaalsContact OD2-CD 3.23Å; D349-K351 WeakPolarHBondContact OD2-CD 3.47Å; D349-K351 VanDerWaalsContact OD2-CE 3.29Å; D349-K351 WeakPolarHBondContact OD2-CE 3.43Å; D349-K351 WeakPolarHBondContact OD2-CG 3.49Å; D349-K351 IonicContact OD2-NZ 3.63Å; D349-K351 PolarHBondContact OD2-NZ 2.8Å
350G91.1Very high87.1Confident4 Ų439.7 Ų39.74%0.04120%0.203CC..SBendtrans73.510.317800000114.2A269 I273 L276 Y346 G347 T348A269-G350 VanDerWaalsContact CB-CA 3.46Å; I273-G350 VanDerWaalsContact CD1-O 3.27Å; I273-G350 WeakPolarHBondContact CD1-O 3.43Å; L276-G350 VanDerWaalsContact CD1-O 3.32Å; L276-G350 WeakPolarHBondContact CD1-O 3.37Å; Y346-G350 VanDerWaalsContact CD1-O 3.25Å; Y346-G350 WeakPolarHBondContact CD1-O 3.38Å; Y346-G350 WeakPolarHBondContact CE1-O 3.23Å; G347-G350 WeakPolarHBondContact O-CA 3.42Å; G347-G350 PolarHBondContact O-N 3.45Å; T348-G350 PolarHBondContact O-N 3.46Å
351K93.1Very high87.5Confident125 Ų12541 Ų4154%0.54320%0.204SC..  trans-79.9149.7168.9-64.4-174-159.2122.60110.5A311 Y346 G347 D349A311-K351 HydrophobicContact CB-CB 3.78Å; Y346-K351 WeakPolarHBondContact CA-O 3.43Å; G347-K351 PolarHBondContact N-O 2.87Å; D349-K351 PolarHBondContact O-N 2.76Å; D349-K351 VanDerWaalsContact OD2-CD 3.23Å; D349-K351 WeakPolarHBondContact OD2-CD 3.47Å; D349-K351 VanDerWaalsContact OD2-CE 3.29Å; D349-K351 WeakPolarHBondContact OD2-CE 3.43Å; D349-K351 WeakPolarHBondContact OD2-CG 3.49Å; D349-K351 IonicContact OD2-NZ 3.63Å; D349-K351 PolarHBondContact OD2-NZ 2.8Å
352E89.5Confident88.4Confident116 Ų11637.8 Ų37.854%0.54219%0.187SC..EExtended strand (participates in β ladder)trans-83137.2177.1-64.6179.6-179.600110.8V344 Y346V344-E352 HydrophobicContact CB-CB 4.07Å; V344-E352 HydrophobicContact CB-CG 4.33Å; V344-E352 HydrophobicContact CG1-CB 4.17Å; V344-E352 HydrophobicContact CG2-CB 4.27Å; V344-E352 HydrophobicContact CG2-CG 3.96Å; Y346-E352 HydrophobicContact CD1-CG 4.08Å; Y346-E352 HydrophobicContact CE1-CG 3.55Å; Y346-E352 PolarHBondContact OH-OE1 3.09Å
353A88.4Confident88.9Confident1 Ų132.4 Ų32.41%0.00817%0.165CC..EExtended strand (participates in β ladder)trans-116.5123.7164.700000108.5A311 V344 V345 I355 L358A311-A353 HydrophobicContact CB-CB 4.43Å; V344-A353 WeakPolarHBondContact CA-O 3.32Å; V345-A353 HydrophobicContact CG2-CB 4.12Å; V345-A353 PolarHBondContact N-O 3.16Å; V345-A353 PolarHBondContact O-N 2.94Å; A353-I355 PolarHBondContact O-N 2.77Å; A353-L358 HydrophobicContact CB-CD1 4Å; A353-L358 HydrophobicContact CB-CD2 4.28Å; A353-L358 HydrophobicContact CB-CG 4.29Å
354S87.7Confident89.1Confident33 Ų3331.6 Ų31.623%0.23116%0.156CC..EExtended strand (participates in β ladder)trans-67.1125.6179.9161.10000110.5Y356 D357 L358S354-Y356 PolarHBondContact O-N 3.44Å; S354-Y356 PolarHBondContact OG-N 3.2Å; S354-D357 VanDerWaalsContact CB-OD1 3.23Å; S354-D357 WeakPolarHBondContact CB-OD1 3.34Å; S354-D357 WeakPolarHBondContact CB-OD2 3.39Å; S354-D357 PolarHBondContact O-N 2.9Å; S354-D357 VanDerWaalsContact O-N 3.13Å; S354-D357 VanDerWaalsContact OG-CG 3.24Å; S354-D357 PolarHBondContact OG-N 3.1Å; S354-D357 PolarHBondContact OG-OD1 2.98Å; S354-L358 WeakPolarHBondContact O-CG 3.45Å; S354-L358 PolarHBondContact O-N 3Å
355I85.7Confident88.9Confident11 Ų1134.3 Ų34.36%0.05618%0.176CC..Hα-helixtrans-60.3-35.7179-64.4168.7000110.4G343 V345 A353 T359 I379 L423 M425G343-I355 WeakPolarHBondContact O-CG1 3.42Å; G343-I355 PolarHBondContact O-N 2.91Å; V345-I355 HydrophobicContact CG1-CD1 4.25Å; V345-I355 HydrophobicContact CG1-CG1 4.07Å; A353-I355 PolarHBondContact O-N 2.77Å; I355-T359 HydrophobicContact CG2-CG2 4.49Å; I355-T359 WeakPolarHBondContact O-CG2 3.08Å; I355-T359 PolarHBondContact O-N 3.24Å; I355-T359 PolarHBondContact O-OG1 3.08Å; I355-T359 VanDerWaalsContact O-OG1 3.09Å; I355-I379 HydrophobicContact CD1-CG2 4.05Å; I355-I379 HydrophobicContact CG2-CG1 4.44Å; I355-L423 HydrophobicContact CG2-CD1 4.21Å; I355-L423 HydrophobicContact CG2-CD2 4.31Å; I355-M425 HydrophobicContact CD1-CE 3.78Å; I355-M425 HydrophobicContact CD1-SD 4.4Å
356Y80.1Confident88.7Confident139 Ų13938.8 Ų38.855%0.54520%0.195SC..Hα-helixtrans-59.2-51.7175178.4-104.4000110.9S354 L358 T359 S360 E418S354-Y356 PolarHBondContact O-N 3.44Å; S354-Y356 PolarHBondContact OG-N 3.2Å; Y356-L358 VanDerWaalsContact C-N 3.34Å; Y356-L358 PolarHBondContact O-N 3.36Å; Y356-T359 PolarHBondContact O-N 2.73Å; Y356-T359 VanDerWaalsContact O-N 3.13Å; Y356-T359 PolarHBondContact O-OG1 2.86Å; Y356-S360 WeakPolarHBondContact O-CB 3.34Å; Y356-S360 PolarHBondContact O-N 2.96Å; Y356-E418 PolarHBondContact OH-OE1 2.71Å
357D83.3Confident88.6Confident70 Ų7037.6 Ų37.637%0.37419%0.191SC..Hα-helixtrans-60.3-45.6-177.7-55.516.7000110.5S354 T359 S360 Y361S354-D357 VanDerWaalsContact CB-OD1 3.23Å; S354-D357 WeakPolarHBondContact CB-OD1 3.34Å; S354-D357 WeakPolarHBondContact CB-OD2 3.39Å; S354-D357 PolarHBondContact O-N 2.9Å; S354-D357 VanDerWaalsContact O-N 3.13Å; S354-D357 VanDerWaalsContact OG-CG 3.24Å; S354-D357 PolarHBondContact OG-N 3.1Å; S354-D357 PolarHBondContact OG-OD1 2.98Å; D357-T359 PolarHBondContact O-N 3.17Å; D357-S360 WeakPolarHBondContact O-CB 3.5Å; D357-S360 PolarHBondContact O-N 3.39Å; D357-S360 VanDerWaalsContact O-N 3.1Å; D357-S360 PolarHBondContact O-OG 3.25Å; D357-Y361 WeakPolarHBondContact O-CD2 3.25Å; D357-Y361 WeakPolarHBondContact O-CE2 3.29Å
358L91.6Very high88.2Confident2 Ų241.9 Ų41.91%0.0122%0.219CC..Hα-helixtrans-60.4-41.4176-63.9-176.9000112.6I314 L318 I336 V345 A353 S354 Y356 S360I314-L358 HydrophobicContact CG2-CD1 4.02Å; I314-L358 HydrophobicContact CG2-CD2 3.69Å; L318-L358 HydrophobicContact CD1-CB 3.74Å; L318-L358 HydrophobicContact CD1-CD2 3.73Å; L318-L358 HydrophobicContact CD1-CG 4.24Å; L318-L358 WeakPolarHBondContact CD1-O 3.38Å; I336-L358 HydrophobicContact CD1-CD1 3.8Å; V345-L358 HydrophobicContact CG2-CD1 3.67Å; A353-L358 HydrophobicContact CB-CD1 4Å; A353-L358 HydrophobicContact CB-CD2 4.28Å; A353-L358 HydrophobicContact CB-CG 4.29Å; S354-L358 WeakPolarHBondContact O-CG 3.45Å; S354-L358 PolarHBondContact O-N 3Å; Y356-L358 VanDerWaalsContact C-N 3.34Å; Y356-L358 PolarHBondContact O-N 3.36Å; L358-S360 VanDerWaalsContact C-N 3.34Å
359T87.4Confident88Confident22 Ų2242.8 Ų42.814%0.13523%0.225CC..Hα-helixtrans-70.6-31.1173.453.50000112.7I355 Y356 D357 Y361 F362 F377 F421I355-T359 HydrophobicContact CG2-CG2 4.49Å; I355-T359 WeakPolarHBondContact O-CG2 3.08Å; I355-T359 PolarHBondContact O-N 3.24Å; I355-T359 PolarHBondContact O-OG1 3.08Å; I355-T359 VanDerWaalsContact O-OG1 3.09Å; Y356-T359 PolarHBondContact O-N 2.73Å; Y356-T359 VanDerWaalsContact O-N 3.13Å; Y356-T359 PolarHBondContact O-OG1 2.86Å; D357-T359 PolarHBondContact O-N 3.17Å; T359-Y361 PolarHBondContact O-N 2.64Å; T359-F362 PolarHBondContact O-N 2.88Å; T359-F377 HydrophobicContact CG2-CB 4.4Å; T359-F377 HydrophobicContact CG2-CD1 3.9Å; T359-F377 HydrophobicContact CG2-CD2 3.86Å; T359-F377 HydrophobicContact CG2-CE1 4.1Å; T359-F377 HydrophobicContact CG2-CE2 4.09Å; T359-F377 HydrophobicContact CG2-CG 3.77Å; T359-F377 HydrophobicContact CG2-CZ 4.2Å; T359-F421 WeakPolarHBondContact O-CE1 3.27Å
360S88.3Confident87.9Confident17 Ų1742.1 Ų42.112%0.11922%0.222CC..Hα-helixtrans-63.6-27.9-173.385.40000113.1Y356 D357 L358 F362 T363 K366Y356-S360 WeakPolarHBondContact O-CB 3.34Å; Y356-S360 PolarHBondContact O-N 2.96Å; D357-S360 WeakPolarHBondContact O-CB 3.5Å; D357-S360 PolarHBondContact O-N 3.39Å; D357-S360 VanDerWaalsContact O-N 3.1Å; D357-S360 PolarHBondContact O-OG 3.25Å; L358-S360 VanDerWaalsContact C-N 3.34Å; S360-F362 PolarHBondContact O-N 3.39Å; S360-T363 WeakPolarHBondContact O-CG2 3.27Å; S360-T363 PolarHBondContact O-N 2.78Å; S360-T363 PolarHBondContact O-OG1 3.27Å; S360-K366 WeakPolarHBondContact O-CD 3.3Å; S360-K366 PolarHBondContact OG-NZ 3.31Å
361Y91.9Very high87.8Confident38 Ų3844.6 Ų44.615%0.14924%0.238CC..THydrogen-bonded Turntrans-53.3-23.4176.1-75.8-84000113.4H315 L318 E319 Q322 D357 T359 K366H315-Y361 AromaticContact ND1-CE2 3.45Å; H315-Y361 WeakPolarHBondContact ND1-CE2 3.46Å; H315-Y361 AromaticContact ND1-CZ 3.59Å; H315-Y361 PolarHBondContact ND1-OH 2.76Å; L318-Y361 HydrophobicContact CB-CD2 4.13Å; L318-Y361 HydrophobicContact CB-CG 4.22Å; L318-Y361 HydrophobicContact CD1-CD2 4.47Å; E319-Y361 HydrophobicContact CB-CD1 4.17Å; E319-Y361 HydrophobicContact CB-CE1 3.78Å; E319-Y361 HydrophobicContact CG-CE1 4.28Å; Q322-Y361 VanDerWaalsContact CG-O 3.25Å; Q322-Y361 WeakPolarHBondContact CG-O 3.3Å; D357-Y361 WeakPolarHBondContact O-CD2 3.25Å; D357-Y361 WeakPolarHBondContact O-CE2 3.29Å; T359-Y361 PolarHBondContact O-N 2.64Å; Y361-K366 WeakPolarHBondContact O-CB 3.35Å
362F93.9Very high87.5Confident0 Ų039.9 Ų39.90%023%0.225CC..THydrogen-bonded Turntrans-111.316.9-173.2-56-87000113.9L318 F332 T359 S360 C367 L370 K375 F377 F421L318-F362 HydrophobicContact CB-CE2 4.02Å; L318-F362 HydrophobicContact CB-CZ 4.21Å; L318-F362 HydrophobicContact CD1-CE2 4.31Å; L318-F362 HydrophobicContact CD2-CE2 4.02Å; L318-F362 HydrophobicContact CD2-CZ 4.13Å; L318-F362 HydrophobicContact CG-CE2 4.33Å; L318-F362 WeakPolarHBondContact O-CZ 3.16Å; F332-F362 HydrophobicContact CD1-CD1 4.13Å; F332-F362 HydrophobicContact CD1-CE1 4.28Å; F332-F362 HydrophobicContact CD1-CG 4.36Å; F332-F362 HydrophobicContact CD2-CE1 4.39Å; F332-F362 AromaticContact CE1-CD1 3.92Å; F332-F362 HydrophobicContact CE1-CD1 3.92Å; F332-F362 HydrophobicContact CE1-CD2 4.08Å; F332-F362 AromaticContact CE1-CE1 3.73Å; F332-F362 HydrophobicContact CE1-CE1 3.73Å; F332-F362 AromaticContact CE1-CE2 3.89Å; F332-F362 HydrophobicContact CE1-CE2 3.89Å; F332-F362 HydrophobicContact CE1-CG 4.09Å; F332-F362 AromaticContact CE1-CZ 3.71Å; F332-F362 HydrophobicContact CE1-CZ 3.71Å; F332-F362 AromaticContact CE2-CE1 3.86Å; F332-F362 HydrophobicContact CE2-CE1 3.86Å; F332-F362 HydrophobicContact CE2-CZ 4.14Å; F332-F362 HydrophobicContact CZ-CD1 4.14Å; F332-F362 AromaticContact CZ-CE1 3.48Å; F332-F362 HydrophobicContact CZ-CE1 3.48Å; F332-F362 VanDerWaalsContact CZ-CE1 3.48Å; F332-F362 AromaticContact CZ-CE2 3.99Å; F332-F362 HydrophobicContact CZ-CE2 3.99Å; F332-F362 AromaticContact CZ-CZ 3.39Å; F332-F362 HydrophobicContact CZ-CZ 3.39Å; T359-F362 PolarHBondContact O-N 2.88Å; S360-F362 PolarHBondContact O-N 3.39Å; F362-C367 HydrophobicContact CD1-CB 4.49Å; F362-L370 HydrophobicContact CD1-CD1 3.81Å; F362-K375 HydrophobicContact CB-CD 3.98Å; F362-K375 WeakPolarHBondContact O-CD 3.23Å; F362-K375 WeakPolarHBondContact O-CE 3.37Å; F362-F377 HydrophobicContact CD2-CE2 4.48Å; F362-F377 AromaticContact CD2-CZ 3.63Å; F362-F377 HydrophobicContact CD2-CZ 3.63Å; F362-F377 HydrophobicContact CE2-CZ 4.07Å; F362-F377 HydrophobicContact CG-CZ 4.39Å; F362-F421 HydrophobicContact CB-CE1 4.34Å; F362-F421 HydrophobicContact CB-CZ 4.21Å; F362-F421 WeakPolarHBondContact O-CZ 3.44Å
363T84Confident87.9Confident8 Ų836.1 Ų36.15%0.04921%0.207CC..SBendtrans-59.8161.1170.360.20000111.5S360 S365 K366 C367 D417 E418S360-T363 WeakPolarHBondContact O-CG2 3.27Å; S360-T363 PolarHBondContact O-N 2.78Å; S360-T363 PolarHBondContact O-OG1 3.27Å; T363-S365 PolarHBondContact O-N 2.97Å; T363-S365 PolarHBondContact OG1-OG 2.84Å; T363-K366 PolarHBondContact O-N 2.9Å; T363-K366 PolarHBondContact OG1-N 2.86Å; T363-C367 PolarHBondContact O-N 3.46Å; T363-D417 WeakPolarHBondContact CB-O 3.35Å; T363-D417 WeakPolarHBondContact CB-OD2 3.44Å; T363-D417 PolarHBondContact OG1-OD2 2.96Å; T363-E418 HydrophobicContact CG2-CG 4.18Å
364G76.8Confident88.3Confident16 Ų1636.1 Ų36.117%0.16521%0.207CC..THydrogen-bonded Turntrans-58.3-27.8179.900000114.3P368 D417G364-P368 VanDerWaalsContact O-CA 3.27Å; G364-P368 WeakPolarHBondContact O-CA 3.38Å; G364-D417 VanDerWaalsContact C-OD1 3.32Å; G364-D417 VanDerWaalsContact CA-OD1 3.26Å; G364-D417 WeakPolarHBondContact CA-OD1 3.35Å; G364-D417 PolarHBondContact N-O 3.32Å; G364-D417 PolarHBondContact N-OD1 3.42Å
365S81.2Confident88.8Confident76 Ų7634.7 Ų34.753%0.53120%0.196SC..THydrogen-bonded Turntrans-79.3-4617859.80000112.2T363 D417T363-S365 PolarHBondContact O-N 2.97Å; T363-S365 PolarHBondContact OG1-OG 2.84Å; S365-D417 WeakPolarHBondContact CB-OD1 3.21Å; S365-D417 WeakPolarHBondContact CB-OD2 3.36Å; S365-D417 PolarHBondContact N-OD1 2.88Å; S365-D417 VanDerWaalsContact OG-CG 3.26Å; S365-D417 PolarHBondContact OG-OD1 2.86Å; S365-D417 PolarHBondContact OG-OD2 2.66Å
366K86Confident89.4Confident93 Ų9334.1 Ų34.140%0.40419%0.194SC..THydrogen-bonded Turntrans-78.7-34.2-179.8-69.4-167.8-163.6168.50113.1Q322 S360 Y361 T363Q322-K366 HydrophobicContact CG-CB 4.41Å; Q322-K366 WeakPolarHBondContact CG-O 2.85Å; Q322-K366 PolarHBondContact NE2-O 3.4Å; S360-K366 WeakPolarHBondContact O-CD 3.3Å; S360-K366 PolarHBondContact OG-NZ 3.31Å; Y361-K366 WeakPolarHBondContact O-CB 3.35Å; T363-K366 PolarHBondContact O-N 2.9Å; T363-K366 PolarHBondContact OG1-N 2.86Å
367C90.7Very high90.3Very high1 Ų127.6 Ų27.61%0.00717%0.168CC..  trans-128.373.1176.8-164.90000112.4Q322 F362 T363 S369 L370Q322-C367 HydrophobicContact CG-CB 4.23Å; Q322-C367 PolarHBondContact O-SG 2.9Å; F362-C367 HydrophobicContact CD1-CB 4.49Å; T363-C367 PolarHBondContact O-N 3.46Å; C367-S369 PolarHBondContact O-N 3.32Å; C367-L370 PolarHBondContact O-N 2.81Å
368P89Confident91Very high89 Ų8924.3 Ų24.358%0.57815%0.15SC*.G310 helixtrans-59-24.4-176.3-26.235.3000115.2G364 L370 S371G364-P368 VanDerWaalsContact O-CA 3.27Å; G364-P368 WeakPolarHBondContact O-CA 3.38Å; P368-L370 PolarHBondContact O-N 2.89Å; P368-S371 VanDerWaalsContact O-CB 3.28Å; P368-S371 WeakPolarHBondContact O-CB 3.27Å; P368-S371 PolarHBondContact O-N 2.83Å; P368-S371 VanDerWaalsContact O-N 3.12Å
369S92.4Very high91.1Very high24 Ų2424.3 Ų24.317%0.16815%0.15CC..G310 helixtrans-69.8-13.8176.9610000113.8A324 H326 C367 K373A324-S369 PolarHBondContact O-OG 3.45Å; H326-S369 PolarHBondContact CD2-OG 2.72Å; H326-S369 PolarHBondContact N-OG 2.97Å; C367-S369 PolarHBondContact O-N 3.32Å; S369-K373 PolarHBondContact O-NZ 2.9Å
370L93.6Very high91.2Very high0 Ų023.5 Ų23.50%015%0.145CC..G310 helixtrans-107.16.3170.8-68.6174.8000114.1H326 F332 F362 C367 P368 G372 K373 K375H326-L370 HydrophobicContact CB-CD2 3.48Å; H326-L370 VanDerWaalsContact CB-CD2 3.48Å; H326-L370 HydrophobicContact CB-CG 3.7Å; F332-L370 HydrophobicContact CB-CD1 3.66Å; F332-L370 HydrophobicContact CB-CD2 3.91Å; F332-L370 HydrophobicContact CB-CG 4.47Å; F332-L370 HydrophobicContact CD2-CD1 4.42Å; F332-L370 HydrophobicContact CG-CD1 3.96Å; F362-L370 HydrophobicContact CD1-CD1 3.81Å; C367-L370 PolarHBondContact O-N 2.81Å; P368-L370 PolarHBondContact O-N 2.89Å; L370-G372 PolarHBondContact O-N 3.21Å; L370-K373 HydrophobicContact CD2-CB 4.44Å; L370-K373 HydrophobicContact CD2-CD 4.26Å; L370-K373 PolarHBondContact O-N 3.01Å; L370-K375 HydrophobicContact CB-CD 4.13Å; L370-K375 HydrophobicContact CB-CG 4.3Å; L370-K375 HydrophobicContact CD1-CG 4.37Å; L370-K375 PolarHBondContact O-NZ 2.98Å
371S89.6Confident90.8Very high55 Ų5522.7 Ų22.739%0.38514%0.139SC..THydrogen-bonded Turntrans-62.8131.3171.7-172.10000110.4P368 K373 I415P368-S371 VanDerWaalsContact O-CB 3.28Å; P368-S371 WeakPolarHBondContact O-CB 3.27Å; P368-S371 PolarHBondContact O-N 2.83Å; P368-S371 VanDerWaalsContact O-N 3.12Å; S371-K373 VanDerWaalsContact C-N 3.27Å; S371-K373 PolarHBondContact O-N 3.37Å; S371-I415 WeakPolarHBondContact OG-CD1 3.38Å
372G87.1Confident90Very high26 Ų2622.2 Ų22.227%0.26814%0.142SC..THydrogen-bonded Turntrans79.10.4-176.200000115.7L370 D420L370-G372 PolarHBondContact O-N 3.21Å; G372-D420 WeakPolarHBondContact CA-OD2 3.4Å
373K97Very high88.9Confident38 Ų3822.5 Ų22.517%0.16514%0.143CC..SBendtrans-113.5145.9-175.8-62.3179.7-173.9169.60111.8H326 K327 K329 S369 L370 S371 K375 D420H326-K373 PolarHBondContact O-NZ 3.44Å; K327-K373 PolarHBondContact O-NZ 3.44Å; K329-K373 WeakPolarHBondContact O-CD 3.45Å; K329-K373 WeakPolarHBondContact O-CE 3.11Å; K329-K373 PolarHBondContact O-NZ 3.14Å; S369-K373 PolarHBondContact O-NZ 2.9Å; L370-K373 HydrophobicContact CD2-CB 4.44Å; L370-K373 HydrophobicContact CD2-CD 4.26Å; L370-K373 PolarHBondContact O-N 3.01Å; S371-K373 VanDerWaalsContact C-N 3.27Å; S371-K373 PolarHBondContact O-N 3.37Å; K373-K375 PolarHBondContact O-N 2.9Å; K373-K375 PolarHBondContact O-NZ 2.95Å; K373-D420 VanDerWaalsContact O-CB 3.31Å; K373-D420 WeakPolarHBondContact O-CB 3.47Å
374P98Very high87.4Confident1 Ų122.7 Ų22.71%0.00615%0.146CC..  trans-64.2128.9177.626.5-36.3000112.4Y248 M250 D330 C331 F332 D420 L492 L496Y248-P374 HydrophobicContact CD1-CG 4.4Å; Y248-P374 HydrophobicContact CD2-CB 4.44Å; Y248-P374 HydrophobicContact CD2-CG 4.48Å; Y248-P374 HydrophobicContact CE2-CB 4.46Å; Y248-P374 HydrophobicContact CG-CG 4.2Å; M250-P374 HydrophobicContact CE-CG 4.09Å; D330-P374 WeakPolarHBondContact O-CD 3.24Å; C331-P374 WeakPolarHBondContact CA-O 3.49Å; C331-P374 HydrophobicContact CB-CG 3.92Å; C331-P374 PolarHBondContact SG-O 2.87Å; C331-P374 VanDerWaalsContact SG-O 3.41Å; F332-P374 PolarHBondContact N-O 3.37Å; P374-D420 CarbonylContact C-O 3.27Å; P374-D420 WeakPolarHBondContact CA-O 3.36Å; P374-L492 HydrophobicContact CB-CD2 4.28Å; P374-L496 HydrophobicContact CB-CD1 4.04Å; P374-L496 HydrophobicContact CB-CD2 3.57Å; P374-L496 HydrophobicContact CB-CG 4.46Å; P374-L496 HydrophobicContact CG-CD1 3.77Å; P374-L496 HydrophobicContact CG-CD2 4.22Å
375K98.2Very high86.1Confident2 Ų226.4 Ų26.41%0.00917%0.17CC..EExtended strand (participates in β ladder)trans-120.7111.7179.5-66.3168-71-69.50108.8F362 L370 K373 A419 D420 F421 L422F362-K375 HydrophobicContact CB-CD 3.98Å; F362-K375 WeakPolarHBondContact O-CD 3.23Å; F362-K375 WeakPolarHBondContact O-CE 3.37Å; L370-K375 HydrophobicContact CB-CD 4.13Å; L370-K375 HydrophobicContact CB-CG 4.3Å; L370-K375 HydrophobicContact CD1-CG 4.37Å; L370-K375 PolarHBondContact O-NZ 2.98Å; K373-K375 PolarHBondContact O-N 2.9Å; K373-K375 PolarHBondContact O-NZ 2.95Å; K375-A419 WeakPolarHBondContact CE-O 3.34Å; K375-A419 PolarHBondContact NZ-O 3.42Å; K375-D420 PolarHBondContact N-O 3.36Å; K375-F421 HydrophobicContact CB-CD1 3.89Å; K375-F421 HydrophobicContact CB-CE1 4.01Å; K375-F421 HydrophobicContact CB-CG 4.24Å; K375-F421 HydrophobicContact CB-CZ 4.46Å; K375-F421 HydrophobicContact CD-CD2 4.44Å; K375-F421 HydrophobicContact CD-CE1 4.2Å; K375-F421 HydrophobicContact CD-CE2 3.94Å; K375-F421 HydrophobicContact CD-CZ 3.82Å; K375-F421 VanDerWaalsContact CE-CD2 3.48Å; K375-F421 CarbonylContact O-C 3.58Å; K375-F421 VanDerWaalsContact O-CA 3.3Å; K375-F421 WeakPolarHBondContact O-CA 3.39Å; K375-L422 PolarHBondContact O-N 3.48Å
376I98.5Very high84Confident0 Ų027.2 Ų27.20%017%0.168CC..EExtended strand (participates in β ladder)trans-118.8129.5-164.3-45.2178.1000110.4F332 I333 C334 F378 L422 L496 F498F332-I376 PolarHBondContact O-N 3.44Å; I333-I376 CarbonylContact C-O 3.57Å; I333-I376 WeakPolarHBondContact CA-O 3.23Å; I333-I376 HydrophobicContact CD1-CD1 4.23Å; I333-I376 HydrophobicContact CG1-CB 4.18Å; I333-I376 HydrophobicContact CG1-CD1 4.12Å; I333-I376 HydrophobicContact CG1-CG1 4.43Å; C334-I376 PolarHBondContact N-O 3.19Å; I376-F378 HydrophobicContact CG2-CD2 4.12Å; I376-F378 HydrophobicContact CG2-CE1 4.08Å; I376-F378 HydrophobicContact CG2-CE2 3.5Å; I376-F378 VanDerWaalsContact CG2-CE2 3.5Å; I376-F378 HydrophobicContact CG2-CZ 3.48Å; I376-F378 VanDerWaalsContact CG2-CZ 3.48Å; I376-L422 CarbonylContact C-O 3.55Å; I376-L422 VanDerWaalsContact CA-O 3.32Å; I376-L422 WeakPolarHBondContact CA-O 3.31Å; I376-L422 HydrophobicContact CG1-CB 4.43Å; I376-L422 HydrophobicContact CG2-CB 4.22Å; I376-L422 HydrophobicContact CG2-CD2 3.95Å; I376-L422 HydrophobicContact CG2-CG 4.08Å; I376-L496 HydrophobicContact CD1-CD2 3.69Å; I376-L496 HydrophobicContact CG1-CD2 4.38Å; I376-F498 HydrophobicContact CD1-CE1 4.4Å; I376-F498 HydrophobicContact CD1-CE2 4.43Å; I376-F498 HydrophobicContact CD1-CZ 3.56Å
377F98.1Very high81.9Confident1 Ų128 Ų280%0.00417%0.172CC..EExtended strand (participates in β ladder)trans-121.4121.1178.8-73-98.1000109.7F332 C334 T359 F362 I379 F421 L422 L423 G424F332-F377 HydrophobicContact CE1-CE2 4.42Å; F332-F377 AromaticContact CE1-CZ 3.95Å; F332-F377 HydrophobicContact CE1-CZ 3.95Å; C334-F377 HydrophobicContact CB-CD1 3.72Å; C334-F377 HydrophobicContact CB-CE1 3.62Å; C334-F377 HydrophobicContact CB-CG 4.46Å; C334-F377 HydrophobicContact CB-CZ 4.28Å; C334-F377 CarbonylContact O-C 3.57Å; C334-F377 VanDerWaalsContact O-CA 3.27Å; C334-F377 WeakPolarHBondContact O-CA 3.31Å; T359-F377 HydrophobicContact CG2-CB 4.4Å; T359-F377 HydrophobicContact CG2-CD1 3.9Å; T359-F377 HydrophobicContact CG2-CD2 3.86Å; T359-F377 HydrophobicContact CG2-CE1 4.1Å; T359-F377 HydrophobicContact CG2-CE2 4.09Å; T359-F377 HydrophobicContact CG2-CG 3.77Å; T359-F377 HydrophobicContact CG2-CZ 4.2Å; F362-F377 HydrophobicContact CD2-CE2 4.48Å; F362-F377 AromaticContact CD2-CZ 3.63Å; F362-F377 HydrophobicContact CD2-CZ 3.63Å; F362-F377 HydrophobicContact CE2-CZ 4.07Å; F362-F377 HydrophobicContact CG-CZ 4.39Å; F377-I379 HydrophobicContact CB-CD1 4.37Å; F377-F421 HydrophobicContact CD2-CD1 4.24Å; F377-F421 HydrophobicContact CD2-CE1 4.46Å; F377-F421 HydrophobicContact CE2-CD1 4.06Å; F377-F421 AromaticContact CE2-CE1 3.85Å; F377-F421 HydrophobicContact CE2-CE1 3.85Å; F377-L422 PolarHBondContact N-O 2.87Å; F377-L423 HydrophobicContact CB-CD1 3.61Å; F377-L423 CarbonylContact O-C 3.58Å; F377-L423 WeakPolarHBondContact O-CA 3.37Å; F377-G424 PolarHBondContact O-N 3.48Å
378F97.8Very high79Confident1 Ų131.5 Ų31.50%0.00419%0.188CC..EExtended strand (participates in β ladder)trans-109.3108.6173.7-66.3-62.3000109.4F296 I333 C334 C335 I336 I376 L447 L465F296-F378 HydrophobicContact CE1-CE2 4.46Å; F296-F378 HydrophobicContact CE2-CD2 4.4Å; F296-F378 HydrophobicContact CE2-CE2 4.31Å; F296-F378 HydrophobicContact CZ-CD2 4.15Å; F296-F378 AromaticContact CZ-CE2 3.62Å; F296-F378 HydrophobicContact CZ-CE2 3.62Å; F296-F378 HydrophobicContact CZ-CZ 4.49Å; I333-F378 HydrophobicContact CG2-CD2 4.02Å; I333-F378 HydrophobicContact CG2-CE2 4.13Å; C334-F378 PolarHBondContact O-N 3.12Å; C335-F378 WeakPolarHBondContact CA-O 3.41Å; I336-F378 PolarHBondContact N-O 3.13Å; I376-F378 HydrophobicContact CG2-CD2 4.12Å; I376-F378 HydrophobicContact CG2-CE1 4.08Å; I376-F378 HydrophobicContact CG2-CE2 3.5Å; I376-F378 VanDerWaalsContact CG2-CE2 3.5Å; I376-F378 HydrophobicContact CG2-CZ 3.48Å; I376-F378 VanDerWaalsContact CG2-CZ 3.48Å; F378-L447 HydrophobicContact CB-CD2 4.38Å; F378-L447 HydrophobicContact CD1-CD2 3.6Å; F378-L447 HydrophobicContact CD2-CD2 4.22Å; F378-L447 HydrophobicContact CE1-CD1 4.08Å; F378-L447 HydrophobicContact CE1-CD2 3.83Å; F378-L447 HydrophobicContact CE2-CD2 4.42Å; F378-L447 HydrophobicContact CG-CD2 3.8Å; F378-L447 HydrophobicContact CZ-CD1 4.34Å; F378-L447 HydrophobicContact CZ-CD2 4.23Å; F378-L465 HydrophobicContact CE1-CD2 4.21Å
379I93.1Very high76.3Confident2 Ų235.8 Ų35.81%0.0120%0.197CC..EExtended strand (participates in β ladder)trans-108.5105.7-172.6-50.8-58.9000109.9I336 V345 I355 F377 A381 L423 G424 M425 A426I336-I379 HydrophobicContact CB-CD1 3.89Å; I336-I379 HydrophobicContact CD1-CD1 3.91Å; I336-I379 HydrophobicContact CG1-CD1 3.96Å; V345-I379 HydrophobicContact CG1-CG2 3.79Å; I355-I379 HydrophobicContact CD1-CG2 4.05Å; I355-I379 HydrophobicContact CG2-CG1 4.44Å; F377-I379 HydrophobicContact CB-CD1 4.37Å; I379-A381 HydrophobicContact CG2-CB 4.17Å; I379-L423 HydrophobicContact CG1-CD1 3.63Å; I379-G424 PolarHBondContact N-O 3.43Å; I379-M425 HydrophobicContact CB-CE 4.19Å; I379-M425 HydrophobicContact CB-SD 3.74Å; I379-M425 HydrophobicContact CG1-SD 3.94Å; I379-M425 HydrophobicContact CG2-CE 4.09Å; I379-M425 HydrophobicContact CG2-SD 4.25Å; I379-A426 WeakPolarHBondContact O-CB 3.2Å; I379-A426 PolarHBondContact O-N 2.92Å
380Q90.8Very high73.3Confident5 Ų537.3 Ų37.32%0.02322%0.217CC..EExtended strand (participates in β ladder)trans-101.777.4174.517440.380.900110I336 L337 S338 A426 S433 T441 I444I336-Q380 PolarHBondContact O-N 3.27Å; L337-Q380 HydrophobicContact CD2-CB 3.74Å; L337-Q380 HydrophobicContact CD2-CG 4.21Å; S338-Q380 PolarHBondContact N-O 3.35Å; S338-Q380 VanDerWaalsContact O-O 3.05Å; Q380-A426 HydrophobicContact CB-CB 4.45Å; Q380-A426 VanDerWaalsContact OE1-CB 3.25Å; Q380-S433 PolarHBondContact NE2-OG 3.29Å; Q380-T441 HydrophobicContact CG-CG2 3.7Å; Q380-T441 WeakPolarHBondContact CG-OG1 3.18Å; Q380-T441 PolarHBondContact OE1-OG1 3.33Å; Q380-I444 HydrophobicContact CB-CD1 3.97Å; Q380-I444 HydrophobicContact CB-CG1 3.8Å; Q380-I444 HydrophobicContact CG-CG1 3.83Å
381A79.4Confident70.3Confident0 Ų043.2 Ų43.20%025%0.253CS..SBendtrans-138.1160.1173.600000110.6V345 I379 S433V345-A381 HydrophobicContact CG1-CB 3.94Å; I379-A381 HydrophobicContact CG2-CB 4.17Å; A381-S433 PolarHBondContact O-OG 2.98Å
382C75.5Confident67.3Low29 Ų2946.6 Ų46.620%0.19627%0.274CS..  trans-67.7156.3166.4-64.50000110.1G340 D341 S433G340-C382 CarbonylContact C-O 3.51Å; G340-C382 WeakPolarHBondContact CA-O 3.31Å; D341-C382 PolarHBondContact N-O 2.92Å; C382-S433 PolarHBondContact SG-N 2.66Å
383Q70.1Confident64.5Low6 Ų653 Ų533%0.02830%0.302CS..  trans-124.319.5176.3-71.3-64.4-70.800112.1D341 K342 M425 T427 N430 C431D341-Q383 PolarHBondContact O-NE2 2.91Å; K342-Q383 WeakPolarHBondContact CA-O 3.47Å; K342-Q383 WeakPolarHBondContact CB-O 3.15Å; K342-Q383 PolarHBondContact N-O 3.03Å; Q383-M425 VanDerWaalsContact CD-CE 3.45Å; Q383-M425 HydrophobicContact CG-CE 3.6Å; Q383-T427 HydrophobicContact CB-CG2 4.17Å; Q383-T427 HydrophobicContact CG-CG2 4.26Å; Q383-N430 CarbonylContact O-C 3.47Å; Q383-N430 WeakPolarHBondContact O-CA 3.29Å; Q383-N430 PolarHBondContact O-N 2.81Å; Q383-C431 PolarHBondContact N-O 3.46Å
384G52.9Low61.3Low11 Ų1160.6 Ų60.611%0.11334%0.338CS..SBendtrans151.9-176.9179.700000111.4D341 N430 C431D341-G384 WeakPolarHBondContact OD1-CA 3.37Å; G384-N430 CarbonylContact C-O 3.58Å; G384-N430 WeakPolarHBondContact CA-O 3.43Å; G384-C431 PolarHBondContact N-O 3.49Å; G384-C431 CarbonylContact O-C 3.31Å
385S49.8Very low58.1Low95 Ų9565.5 Ų65.566%0.66438%0.378SS*.SBendtrans-100-2.2-174.457.20000115
386N36.8Very low54.6Low93 Ų9369.2 Ų69.250%0.49742%0.417SS..BIsolated β-bridgetrans-79.9144.2-176.3-61-41.3000112N430 C431 V432N386-N430 VanDerWaalsContact CB-O 3.28Å; N386-N430 WeakPolarHBondContact CB-O 3.46Å; N386-N430 PolarHBondContact N-O 3.12Å; N386-N430 VanDerWaalsContact N-O 3.08Å; N386-N430 PolarHBondContact ND2-O 3.45Å; N386-C431 VanDerWaalsContact O-CA 3.27Å; N386-C431 WeakPolarHBondContact O-CA 3.32Å; N386-V432 PolarHBondContact O-N 3.47Å
387F40.8Very low51.2Low109 Ų10978.9 Ų78.948%0.47846%0.459SS..PPolyproline II helixtrans-87.3128.4167.7-59.3-75.6000109.6K389 V432 Y434F387-K389 PolarHBondContact O-N 2.93Å; F387-V432 HydrophobicContact CD1-CG2 3.73Å; F387-V432 HydrophobicContact CE1-CG2 4.05Å; F387-Y434 WeakPolarHBondContact CD1-OH 3.21Å
388Q30.1Very low47.8Very low74 Ų7488.3 Ų88.335%0.34650%0.503SS..BIsolated β-bridgetrans-67.3123.5175.8-174.764.49.600109.4C431 K483Q388-C431 PolarHBondContact OE1-SG 3.35Å; Q388-C431 VanDerWaalsContact OE1-SG 3.38Å; Q388-K483 HydrophobicContact CB-CB 4.44Å; Q388-K483 WeakPolarHBondContact CB-O 3.32Å; Q388-K483 PolarHBondContact O-N 3.22Å
389K33.3Very low44.4Very low179 Ų17996.6 Ų96.678%0.77854%0.542SS*.PPolyproline II helixtrans-78132.3176.1-64.2179.8-178.3176.50109.5F387F387-K389 PolarHBondContact O-N 2.93Å
390G28.8Very low41.1Very low56 Ų56104.2 Ų104.258%0.57758%0.578SS**PPolyproline II helixtrans-79145.8170.100000111.9
391V30.3Very low37.9Very low125 Ų125110.5 Ų110.576%0.75861%0.611SS**  trans-124.6146.5172.8-174.40000107.1
392P26.8Very low35.3Very low126 Ų126118 Ų11882%0.81865%0.646SS**  trans-66.2135.4172.8-17.932.1000111.3
393D28.8Very low32.7Very low160 Ų160122.9 Ų122.986%0.85668%0.675SS**  trans-94.8133.7177-98.9-30.8000111.6
394E30.1Very low30.5Very low198 Ų198128.6 Ų128.693%0.92571%0.705SS**  trans-118119159.7-69.5-172.2-176.400107.8
395A29.6Very low29Very low104 Ų104137 Ų13786%0.8674%0.742SS**  trans-97.2147-166.100000113.9
396G26.1Very low27.7Very low79 Ų79138.4 Ų138.481%0.81475%0.746SS**  trans-167.8119.7169.100000113
397F27.3Very low27Very low203 Ų203142.2 Ų142.289%0.8977%0.766SS**  trans-98.7147.3171.5-74.5-103.3000110.3
398E25.1Very low26.2Very low200 Ų200142.4 Ų142.494%0.93578%0.781SS**  trans-145.4164.7145.7-71.2-156.3155.300111.1
399Q26.1Very low25.9Very low174 Ų174142.9 Ų142.981%0.81379%0.793SS**  trans-128.1177.5-168.4-77-175.6-30.900113
400Q24.7Very low25.9Very low163 Ų163140.5 Ų140.576%0.76280%0.799SS**  trans94.7144.5160.2-58.7-172.837.800116.4
401N24Very low25.9Very low136 Ų136144.1 Ų144.173%0.72780%0.8SS**  cis-155.6172.3-3.6-105.7-17000112.7
402H23.6Very low25.8Very low157 Ų157146.5 Ų146.573%0.72780%0.8SS**  trans-48.7159-177.2-75.1-85.6000120.4
403T21Very low26.2Very low133 Ų133147.5 Ų147.582%0.81680%0.799SS**  -153.6150.6116.3-60.90000109.6
404L23.7Very low26.7Very low126 Ų126149.6 Ų149.666%0.6680%0.796SS**  trans-133.2142.7175.6-77.2170.3000109.8
405E22.1Very low27.2Very low188 Ų188142.4 Ų142.488%0.87976%0.764SS**  trans-129.5152.1159.2-68.5-166.7158.800110
406V23.1Very low28Very low124 Ų124141.8 Ų141.875%0.75275%0.751SS**  trans-138.8130.7-170.2175.60000108.5
407D20.8Very low29.4Very low173 Ų173141.3 Ų141.393%0.92573%0.73SS**  trans-124.1144.3158.2-100.1-39.7000110.9
408S24.2Very low31.6Very low113 Ų113136.3 Ų136.379%0.7971%0.709SS**  trans-122.5127-170.3-177.80000110.7
409S25.2Very low33.6Very low84 Ų84127 Ų12759%0.58767%0.666SS**  trans-142.1142.116249.60000110.2H411S409-H411 PolarHBondContact O-N 3.46Å; S409-H411 PolarHBondContact O-ND1 2.82Å; S409-H411 PolarHBondContact OG-CE1 3.45Å; S409-H411 PolarHBondContact OG-ND1 2.94Å
410S33.3Very low36.8Very low129 Ų129118.7 Ų118.790%0.90263%0.628SS**  trans-7481.4-166.7530000112.9
411H28Very low40Very low131 Ų131112.1 Ų112.161%0.60660%0.596SS**  trans-82.7147173.8-70.373.1000111.2S409 N413S409-H411 PolarHBondContact O-N 3.46Å; S409-H411 PolarHBondContact O-ND1 2.82Å; S409-H411 PolarHBondContact OG-CE1 3.45Å; S409-H411 PolarHBondContact OG-ND1 2.94Å; H411-N413 PolarHBondContact O-N 2.8Å; H411-N413 VanDerWaalsContact O-N 3.1Å
412K28.7Very low43.5Very low175 Ų175105.6 Ų105.676%0.76156%0.562SS**  trans-63.4111.6157.9-72.1177.1-177.8171.40106.1Y414K412-Y414 VanDerWaalsContact C-N 3.33Å; K412-Y414 HydrophobicContact CB-CD2 4.49Å; K412-Y414 HydrophobicContact CB-CE2 3.92Å; K412-Y414 WeakPolarHBondContact O-CD2 3.32Å; K412-Y414 PolarHBondContact O-N 2.82Å
413N35.1Very low46.8Very low148 Ų148100 Ų10079%0.79154%0.537SS*.  trans-72.983.1-169.6-71.5-43.9000112H411H411-N413 PolarHBondContact O-N 2.8Å; H411-N413 VanDerWaalsContact O-N 3.1Å
414Y39.3Very low50.2Low204 Ų20493.7 Ų93.780%0.850%0.498SS*.  trans-66.2145.1161.6-61.9-83.9000109.3K412K412-Y414 VanDerWaalsContact C-N 3.33Å; K412-Y414 HydrophobicContact CB-CD2 4.49Å; K412-Y414 HydrophobicContact CB-CE2 3.92Å; K412-Y414 WeakPolarHBondContact O-CD2 3.32Å; K412-Y414 PolarHBondContact O-N 2.82Å
415I39.8Very low53.2Low47 Ų4788.5 Ų88.524%0.24147%0.471CS..  trans-124149.1-179.772.7169.2000107.8S371 R493S371-I415 WeakPolarHBondContact OG-CD1 3.38Å; I415-R493 VanDerWaalsContact CD1-NH2 3.35Å
416P46.3Very low55.8Low90 Ų9079.6 Ų79.658%0.58443%0.429SS*.  trans-57.7145.1177.1-23.432.9000111.8E418 A419P416-E418 VanDerWaalsContact C-N 3.3Å; P416-E418 PolarHBondContact O-N 2.85Å; P416-A419 HydrophobicContact CB-CB 4.16Å; P416-A419 HydrophobicContact CG-CB 4.47Å; P416-A419 WeakPolarHBondContact O-CB 3.35Å; P416-A419 PolarHBondContact O-N 3.22Å
417D56.6Low57.7Low70 Ų7073.8 Ų73.837%0.37439%0.394SS..THydrogen-bonded Turntrans-64.3-35.7-171.7-163.630.9000113.2T363 G364 S365 A419T363-D417 WeakPolarHBondContact CB-O 3.35Å; T363-D417 WeakPolarHBondContact CB-OD2 3.44Å; T363-D417 PolarHBondContact OG1-OD2 2.96Å; G364-D417 VanDerWaalsContact C-OD1 3.32Å; G364-D417 VanDerWaalsContact CA-OD1 3.26Å; G364-D417 WeakPolarHBondContact CA-OD1 3.35Å; G364-D417 PolarHBondContact N-O 3.32Å; G364-D417 PolarHBondContact N-OD1 3.42Å; S365-D417 WeakPolarHBondContact CB-OD1 3.21Å; S365-D417 WeakPolarHBondContact CB-OD2 3.36Å; S365-D417 PolarHBondContact N-OD1 2.88Å; S365-D417 VanDerWaalsContact OG-CG 3.26Å; S365-D417 PolarHBondContact OG-OD1 2.86Å; S365-D417 PolarHBondContact OG-OD2 2.66Å; D417-A419 VanDerWaalsContact C-N 3.31Å; D417-A419 PolarHBondContact O-N 2.93Å
418E72.4Confident59.3Low97 Ų9767 Ų6745%0.45336%0.359SS..THydrogen-bonded Turntrans-90.719.2175.5-57.2-170.1171.900112.9Y356 T363 P416 F421 T491Y356-E418 PolarHBondContact OH-OE1 2.71Å; T363-E418 HydrophobicContact CG2-CG 4.18Å; P416-E418 VanDerWaalsContact C-N 3.3Å; P416-E418 PolarHBondContact O-N 2.85Å; E418-F421 WeakPolarHBondContact O-CD2 3.37Å; E418-T491 WeakPolarHBondContact O-CB 3.24Å; E418-T491 PolarHBondContact O-OG1 2.72Å
419A68.4Low61.3Low5 Ų568.5 Ų68.54%0.04135%0.351CS..THydrogen-bonded Turntrans-77.8157.1178.200000113.8K375 P416 D417 F421K375-A419 WeakPolarHBondContact CE-O 3.34Å; K375-A419 PolarHBondContact NZ-O 3.42Å; P416-A419 HydrophobicContact CB-CB 4.16Å; P416-A419 HydrophobicContact CG-CB 4.47Å; P416-A419 WeakPolarHBondContact O-CB 3.35Å; P416-A419 PolarHBondContact O-N 3.22Å; D417-A419 VanDerWaalsContact C-N 3.31Å; D417-A419 PolarHBondContact O-N 2.93Å; A419-F421 VanDerWaalsContact C-N 3.35Å
420D91.6Very high62.9Low0 Ų067.5 Ų67.50%034%0.339CS..THydrogen-bonded Turntrans66.229.9176.7-44.9-53.5000114.2Y248 G372 K373 P374 K375 T491 R493Y248-D420 HydrophobicContact CE1-CB 4.18Å; Y248-D420 WeakPolarHBondContact OH-CB 3.35Å; Y248-D420 VanDerWaalsContact OH-CG 3.31Å; Y248-D420 PolarHBondContact OH-OD1 2.96Å; G372-D420 WeakPolarHBondContact CA-OD2 3.4Å; K373-D420 VanDerWaalsContact O-CB 3.31Å; K373-D420 WeakPolarHBondContact O-CB 3.47Å; P374-D420 CarbonylContact C-O 3.27Å; P374-D420 WeakPolarHBondContact CA-O 3.36Å; K375-D420 PolarHBondContact N-O 3.36Å; D420-T491 PolarHBondContact N-O 2.87Å; D420-T491 PolarHBondContact N-OG1 2.94Å; D420-R493 IonicContact OD1-CZ 2.89Å; D420-R493 IonicContact OD1-NE 3.43Å; D420-R493 PolarHBondContact OD1-NE 3.48Å; D420-R493 IonicContact OD1-NH2 2.69Å; D420-R493 PolarHBondContact OD1-NH2 3.27Å; D420-R493 IonicContact OD2-CZ 3.37Å; D420-R493 IonicContact OD2-NE 3.38Å; D420-R493 IonicContact OD2-NH2 2.92Å; D420-R493 PolarHBondContact OD2-NH2 3.21Å
421F92.7Very high63.9Low24 Ų2461.7 Ų61.711%0.10530%0.299CS..EExtended strand (participates in β ladder)trans-95151.2171-78.1-99.8000113T359 F362 K375 F377 E418 A419 F490 T491 L492T359-F421 WeakPolarHBondContact O-CE1 3.27Å; F362-F421 HydrophobicContact CB-CE1 4.34Å; F362-F421 HydrophobicContact CB-CZ 4.21Å; F362-F421 WeakPolarHBondContact O-CZ 3.44Å; K375-F421 HydrophobicContact CB-CD1 3.89Å; K375-F421 HydrophobicContact CB-CE1 4.01Å; K375-F421 HydrophobicContact CB-CG 4.24Å; K375-F421 HydrophobicContact CB-CZ 4.46Å; K375-F421 HydrophobicContact CD-CD2 4.44Å; K375-F421 HydrophobicContact CD-CE1 4.2Å; K375-F421 HydrophobicContact CD-CE2 3.94Å; K375-F421 HydrophobicContact CD-CZ 3.82Å; K375-F421 VanDerWaalsContact CE-CD2 3.48Å; K375-F421 CarbonylContact O-C 3.58Å; K375-F421 VanDerWaalsContact O-CA 3.3Å; K375-F421 WeakPolarHBondContact O-CA 3.39Å; F377-F421 HydrophobicContact CD2-CD1 4.24Å; F377-F421 HydrophobicContact CD2-CE1 4.46Å; F377-F421 HydrophobicContact CE2-CD1 4.06Å; F377-F421 AromaticContact CE2-CE1 3.85Å; F377-F421 HydrophobicContact CE2-CE1 3.85Å; E418-F421 WeakPolarHBondContact O-CD2 3.37Å; A419-F421 VanDerWaalsContact C-N 3.35Å; F421-F490 CarbonylContact O-C 3.43Å; F421-F490 WeakPolarHBondContact O-CA 3.29Å; F421-T491 PolarHBondContact N-OG1 3.37Å; F421-T491 PolarHBondContact O-N 3.37Å; F421-L492 PolarHBondContact O-N 2.91Å
422L96.6Very high65.6Low0 Ų056.5 Ų56.50%028%0.276CS..EExtended strand (participates in β ladder)trans-137.8116.7167.2170.662.9000109.2K375 I376 F377 I461 L462 L465 P488 F490 L492K375-L422 PolarHBondContact O-N 3.48Å; I376-L422 CarbonylContact C-O 3.55Å; I376-L422 VanDerWaalsContact CA-O 3.32Å; I376-L422 WeakPolarHBondContact CA-O 3.31Å; I376-L422 HydrophobicContact CG1-CB 4.43Å; I376-L422 HydrophobicContact CG2-CB 4.22Å; I376-L422 HydrophobicContact CG2-CD2 3.95Å; I376-L422 HydrophobicContact CG2-CG 4.08Å; F377-L422 PolarHBondContact N-O 2.87Å; L422-I461 HydrophobicContact CD2-CB 4.31Å; L422-I461 HydrophobicContact CD2-CG1 3.59Å; L422-I461 HydrophobicContact CD2-CG2 3.69Å; L422-L462 HydrophobicContact CD1-CD2 3.97Å; L422-L465 HydrophobicContact CD1-CD1 3.97Å; L422-L465 HydrophobicContact CD2-CD1 3.94Å; L422-L465 HydrophobicContact CG-CD1 4.36Å; L422-P488 HydrophobicContact CD1-CB 4.45Å; L422-F490 HydrophobicContact CD1-CB 3.88Å; L422-L492 HydrophobicContact CB-CD1 4.14Å; L422-L492 HydrophobicContact CB-CD2 4.3Å; L422-L492 HydrophobicContact CB-CG 4.22Å; L422-L492 HydrophobicContact CD2-CD1 4.27Å
423L93Very high67.5Low40 Ų4049.1 Ų49.121%0.20925%0.246CC..EExtended strand (participates in β ladder)trans-109.1103.7177.4-18064.2000109.4I355 F377 I379 M425 P488 T489I355-L423 HydrophobicContact CG2-CD1 4.21Å; I355-L423 HydrophobicContact CG2-CD2 4.31Å; F377-L423 HydrophobicContact CB-CD1 3.61Å; F377-L423 CarbonylContact O-C 3.58Å; F377-L423 WeakPolarHBondContact O-CA 3.37Å; I379-L423 HydrophobicContact CG1-CD1 3.63Å; L423-M425 HydrophobicContact CD1-SD 3.91Å; L423-M425 HydrophobicContact CD2-CG 4.32Å; L423-M425 HydrophobicContact CD2-SD 3.97Å; L423-M425 HydrophobicContact CG-CG 4.11Å; L423-M425 HydrophobicContact CG-SD 3.84Å; L423-P488 CarbonylContact O-C 3.58Å; L423-P488 WeakPolarHBondContact O-CA 3.13Å; L423-T489 PolarHBondContact N-O 2.79Å; L423-T489 PolarHBondContact O-N 3.11Å
424G92.9Very high69.3Low0 Ų043.3 Ų43.30%021%0.214CC..EExtended strand (participates in β ladder)trans-88.6100.1172.900000111.3F377 I379 Y443F377-G424 PolarHBondContact O-N 3.48Å; I379-G424 PolarHBondContact N-O 3.43Å; G424-Y443 WeakPolarHBondContact CA-OH 3.4Å; G424-Y443 PolarHBondContact O-OH 2.88Å
425M87.4Confident71.3Confident17 Ų1737 Ų378%0.08419%0.188CC..EExtended strand (participates in β ladder)trans-87.1132.5174.9-60-62.7-64.400110.8I355 I379 Q383 L423 T427 P486 Q487I355-M425 HydrophobicContact CD1-CE 3.78Å; I355-M425 HydrophobicContact CD1-SD 4.4Å; I379-M425 HydrophobicContact CB-CE 4.19Å; I379-M425 HydrophobicContact CB-SD 3.74Å; I379-M425 HydrophobicContact CG1-SD 3.94Å; I379-M425 HydrophobicContact CG2-CE 4.09Å; I379-M425 HydrophobicContact CG2-SD 4.25Å; Q383-M425 VanDerWaalsContact CD-CE 3.45Å; Q383-M425 HydrophobicContact CG-CE 3.6Å; L423-M425 HydrophobicContact CD1-SD 3.91Å; L423-M425 HydrophobicContact CD2-CG 4.32Å; L423-M425 HydrophobicContact CD2-SD 3.97Å; L423-M425 HydrophobicContact CG-CG 4.11Å; L423-M425 HydrophobicContact CG-SD 3.84Å; M425-T427 PolarHBondContact O-N 3.01Å; M425-P486 WeakPolarHBondContact O-CA 3.04Å; M425-P486 WeakPolarHBondContact O-CB 3.25Å; M425-Q487 VanDerWaalsContact CB-O 3.31Å; M425-Q487 WeakPolarHBondContact CB-O 3.48Å; M425-Q487 PolarHBondContact N-O 3.03Å; M425-Q487 VanDerWaalsContact N-O 3.17Å; M425-Q487 PolarHBondContact O-N 3.22Å
426A76.3Confident73Confident0 Ų037.2 Ų37.20%019%0.19CC..SBendtrans-63.8-22.2177.700000114.6I379 Q380 Y443 Q484 P486I379-A426 WeakPolarHBondContact O-CB 3.2Å; I379-A426 PolarHBondContact O-N 2.92Å; Q380-A426 HydrophobicContact CB-CB 4.45Å; Q380-A426 VanDerWaalsContact OE1-CB 3.25Å; A426-Y443 HydrophobicContact CB-CD1 3.48Å; A426-Y443 VanDerWaalsContact CB-CD1 3.48Å; A426-Y443 HydrophobicContact CB-CE1 4.22Å; A426-Y443 HydrophobicContact CB-CG 3.65Å; A426-Q484 PolarHBondContact O-NE2 2.93Å; A426-P486 WeakPolarHBondContact O-CA 3.43Å
427T62Low74.3Confident3 Ų336.9 Ų36.92%0.01819%0.188CC..SBendtrans-152.5151.3-178.5-162.80000111.5Q383 M425 C431 V432 M485Q383-T427 HydrophobicContact CB-CG2 4.17Å; Q383-T427 HydrophobicContact CG-CG2 4.26Å; M425-T427 PolarHBondContact O-N 3.01Å; T427-C431 VanDerWaalsContact CG2-O 3.25Å; T427-C431 WeakPolarHBondContact CG2-O 3.47Å; T427-V432 WeakPolarHBondContact CB-O 3.27Å; T427-V432 PolarHBondContact OG1-O 2.74Å; T427-M485 CarbonylContact C-O 3.48Å; T427-M485 VanDerWaalsContact CA-O 3.27Å; T427-M485 WeakPolarHBondContact CA-O 3.33Å
428V56.4Low75.2Confident31 Ų3138.7 Ų38.719%0.18820%0.201CC..  trans-59.9156.8172.7-690000112.4C431 M485 Q487V428-C431 HydrophobicContact CG2-CB 3.96Å; V428-C431 PolarHBondContact O-N 2.93Å; V428-M485 HydrophobicContact CG1-CB 4.21Å; V428-M485 HydrophobicContact CG1-CG 4.23Å; V428-M485 PolarHBondContact N-O 3.08Å; V428-Q487 HydrophobicContact CG1-CB 4.11Å
429K65.8Low75.5Confident143 Ų14338.9 Ų38.962%0.62221%0.205SC*.THydrogen-bonded Turntrans-54.2141.9179-68178.6179.9174.80111.9C431K429-C431 VanDerWaalsContact C-N 3.26Å; K429-C431 PolarHBondContact O-N 3.31Å
430N57.4Low76.3Confident63 Ų6338.8 Ų38.834%0.33720%0.204SC..THydrogen-bonded Turntrans72.7-1.2-177.3-34.1-81.4000115.7Q383 G384 N386Q383-N430 CarbonylContact O-C 3.47Å; Q383-N430 WeakPolarHBondContact O-CA 3.29Å; Q383-N430 PolarHBondContact O-N 2.81Å; G384-N430 CarbonylContact C-O 3.58Å; G384-N430 WeakPolarHBondContact CA-O 3.43Å; N386-N430 VanDerWaalsContact CB-O 3.28Å; N386-N430 WeakPolarHBondContact CB-O 3.46Å; N386-N430 PolarHBondContact N-O 3.12Å; N386-N430 VanDerWaalsContact N-O 3.08Å; N386-N430 PolarHBondContact ND2-O 3.45Å
431C55.9Low76.1Confident8 Ų838.8 Ų38.85%0.05421%0.205CC..BIsolated β-bridgetrans-107.2159.8-175.5-70.10000114.7Q383 G384 N386 Q388 T427 V428 K429Q383-C431 PolarHBondContact N-O 3.46Å; G384-C431 PolarHBondContact N-O 3.49Å; G384-C431 CarbonylContact O-C 3.31Å; N386-C431 VanDerWaalsContact O-CA 3.27Å; N386-C431 WeakPolarHBondContact O-CA 3.32Å; Q388-C431 PolarHBondContact OE1-SG 3.35Å; Q388-C431 VanDerWaalsContact OE1-SG 3.38Å; T427-C431 VanDerWaalsContact CG2-O 3.25Å; T427-C431 WeakPolarHBondContact CG2-O 3.47Å; V428-C431 HydrophobicContact CG2-CB 3.96Å; V428-C431 PolarHBondContact O-N 2.93Å; K429-C431 VanDerWaalsContact C-N 3.26Å; K429-C431 PolarHBondContact O-N 3.31Å
432V63.6Low76Confident22 Ų2239.9 Ų39.913%0.13321%0.208CC..  trans-76.9163.9173-60.30000112.4N386 F387 T427 Y434N386-V432 PolarHBondContact O-N 3.47Å; F387-V432 HydrophobicContact CD1-CG2 3.73Å; F387-V432 HydrophobicContact CE1-CG2 4.05Å; T427-V432 WeakPolarHBondContact CB-O 3.27Å; T427-V432 PolarHBondContact OG1-O 2.74Å; V432-Y434 HydrophobicContact CG2-CE2 3.99Å
433S67.9Low76Confident19 Ų1940 Ų4013%0.13321%0.208CC..  trans-125.9147.4168.5640000109.9Q380 A381 C382Q380-S433 PolarHBondContact NE2-OG 3.29Å; A381-S433 PolarHBondContact O-OG 2.98Å; C382-S433 PolarHBondContact SG-N 2.66Å
434Y73.3Confident76.1Confident27 Ų2738.1 Ų38.111%0.10620%0.198CC..  trans-100.9138.4-171.7-68.6-91.9000113.2F387 V432 T441 W442 D477 G482 Q484F387-Y434 WeakPolarHBondContact CD1-OH 3.21Å; V432-Y434 HydrophobicContact CG2-CE2 3.99Å; Y434-T441 WeakPolarHBondContact O-CA 3.38Å; Y434-T441 WeakPolarHBondContact O-CB 3.48Å; Y434-W442 HydrophobicContact CD1-CH2 4.02Å; Y434-W442 HydrophobicContact CD1-CZ2 4.34Å; Y434-W442 HydrophobicContact CD1-CZ3 4.4Å; Y434-W442 AromaticContact CD2-CE3 3.86Å; Y434-W442 HydrophobicContact CD2-CE3 3.86Å; Y434-W442 AromaticContact CD2-CH2 3.92Å; Y434-W442 HydrophobicContact CD2-CH2 3.92Å; Y434-W442 AromaticContact CD2-CZ3 3.46Å; Y434-W442 HydrophobicContact CD2-CZ3 3.46Å; Y434-W442 VanDerWaalsContact CD2-CZ3 3.46Å; Y434-W442 HydrophobicContact CE2-CH2 4.43Å; Y434-W442 HydrophobicContact CE2-CZ3 4.07Å; Y434-W442 HydrophobicContact CG-CD2 4.31Å; Y434-W442 AromaticContact CG-CE3 3.97Å; Y434-W442 HydrophobicContact CG-CE3 3.97Å; Y434-W442 AromaticContact CG-CH2 3.69Å; Y434-W442 HydrophobicContact CG-CH2 3.69Å; Y434-W442 HydrophobicContact CG-CZ2 4.09Å; Y434-W442 AromaticContact CG-CZ3 3.65Å; Y434-W442 HydrophobicContact CG-CZ3 3.65Å; Y434-W442 PolarHBondContact O-N 2.69Å; Y434-D477 HydrophobicContact CD1-CB 4.12Å; Y434-D477 HydrophobicContact CE1-CB 3.49Å; Y434-D477 VanDerWaalsContact CE1-CB 3.49Å; Y434-D477 WeakPolarHBondContact CE1-OD2 3.4Å; Y434-G482 WeakPolarHBondContact OH-CA 3.48Å; Y434-Q484 HydrophobicContact CD2-CB 3.95Å; Y434-Q484 HydrophobicContact CE2-CB 4.32Å
435R80.8Confident76.3Confident70 Ų7040.7 Ų40.726%0.26421%0.211SC..EExtended strand (participates in β ladder)trans-127.5123176.8-177.4162.942.673.82.9110.2R282 K283 T441R282-R435 VanDerWaalsContact C-NH1 3.34Å; R282-R435 VanDerWaalsContact CA-CZ 3.45Å; K283-R435 WeakPolarHBondContact O-CD 3.44Å; K283-R435 PolarHBondContact O-NH1 2.84Å; R435-T441 HydrophobicContact CB-CG2 3.65Å; R435-T441 HydrophobicContact CG-CG2 3.78Å
436D75.8Confident76.7Confident53 Ų5340 Ų4028%0.28321%0.207SC..EExtended strand (participates in β ladder)trans-82.8125.3164.5-173.2-50000108.7V438 N439 G440D436-V438 PolarHBondContact O-N 2.78Å; D436-V438 VanDerWaalsContact O-N 3.17Å; D436-V438 WeakPolarHBondContact OD1-CA 3.27Å; D436-V438 WeakPolarHBondContact OD1-CB 3.18Å; D436-V438 PolarHBondContact OD1-N 3.26Å; D436-N439 HydrophobicContact CB-CB 3.96Å; D436-N439 VanDerWaalsContact CG-ND2 3.26Å; D436-N439 PolarHBondContact OD1-N 2.66Å; D436-N439 PolarHBondContact OD1-ND2 2.98Å; D436-N439 PolarHBondContact OD2-ND2 2.7Å; D436-G440 WeakPolarHBondContact CA-O 3.2Å; D436-G440 WeakPolarHBondContact CB-O 3.27Å; D436-G440 PolarHBondContact N-O 3.44Å; D436-G440 PolarHBondContact O-N 2.87Å
437P73.7Confident77.7Confident82 Ų8240 Ų4053%0.53221%0.207SC..THydrogen-bonded Turntrans-64.3-14.1180-23.434.8000115.9K283K283-P437 HydrophobicContact CB-CB 4.31Å
438V76.1Confident79.4Confident109 Ų10939.8 Ų39.866%0.66121%0.206SC*.THydrogen-bonded Turntrans-111-38.7-178.4-177.40000111.1C287 D436C287-V438 PolarHBondContact SG-O 2.76Å; D436-V438 PolarHBondContact O-N 2.78Å; D436-V438 VanDerWaalsContact O-N 3.17Å; D436-V438 WeakPolarHBondContact OD1-CA 3.27Å; D436-V438 WeakPolarHBondContact OD1-CB 3.18Å; D436-V438 PolarHBondContact OD1-N 3.26Å
439N78.5Confident81.4Confident101 Ų10142.6 Ų42.654%0.5422%0.217SC..THydrogen-bonded Turntrans-103.3-7.7-171.4-57.4-63.3000114.6D436 Q445D436-N439 HydrophobicContact CB-CB 3.96Å; D436-N439 VanDerWaalsContact CG-ND2 3.26Å; D436-N439 PolarHBondContact OD1-N 2.66Å; D436-N439 PolarHBondContact OD1-ND2 2.98Å; D436-N439 PolarHBondContact OD2-ND2 2.7Å; N439-Q445 VanDerWaalsContact O-CD 3.27Å; N439-Q445 WeakPolarHBondContact O-CG 3.32Å
440G85Confident82.8Confident2 Ų235.8 Ų35.82%0.02119%0.188CC..EExtended strand (participates in β ladder)trans91.2-169.1-175.300000114D288 D436D288-G440 VanDerWaalsContact OD1-CA 3.27Å; D288-G440 WeakPolarHBondContact OD1-CA 3.29Å; D436-G440 WeakPolarHBondContact CA-O 3.2Å; D436-G440 WeakPolarHBondContact CB-O 3.27Å; D436-G440 PolarHBondContact N-O 3.44Å; D436-G440 PolarHBondContact O-N 2.87Å
441T88Confident84.7Confident1 Ų132.8 Ų32.81%0.00617%0.172CC..EExtended strand (participates in β ladder)trans-86.7145.5-178.357.70000112.7D288 Q380 Y434 R435 Y443 I444 Q445D288-T441 VanDerWaalsContact CG-N 3.28Å; D288-T441 VanDerWaalsContact CG-OG1 3.3Å; D288-T441 PolarHBondContact OD1-N 2.89Å; D288-T441 WeakPolarHBondContact OD2-CB 3.43Å; D288-T441 WeakPolarHBondContact OD2-CG2 3.34Å; D288-T441 PolarHBondContact OD2-N 3.31Å; D288-T441 PolarHBondContact OD2-OG1 2.96Å; Q380-T441 HydrophobicContact CG-CG2 3.7Å; Q380-T441 WeakPolarHBondContact CG-OG1 3.18Å; Q380-T441 PolarHBondContact OE1-OG1 3.33Å; Y434-T441 WeakPolarHBondContact O-CA 3.38Å; Y434-T441 WeakPolarHBondContact O-CB 3.48Å; R435-T441 HydrophobicContact CB-CG2 3.65Å; R435-T441 HydrophobicContact CG-CG2 3.78Å; T441-Y443 PolarHBondContact O-N 3.32Å; T441-I444 PolarHBondContact O-N 2.84Å; T441-I444 WeakPolarHBondContact OG1-CB 3.43Å; T441-I444 WeakPolarHBondContact OG1-CG1 3.27Å; T441-I444 PolarHBondContact OG1-N 3.45Å; T441-Q445 WeakPolarHBondContact O-CB 3.09Å; T441-Q445 VanDerWaalsContact O-CG 3.26Å; T441-Q445 WeakPolarHBondContact O-CG 3.3Å; T441-Q445 PolarHBondContact O-N 3.05Å
442W90.5Very high86.6Confident47 Ų4736.5 Ų36.518%0.17819%0.185CC..Hα-helixtrans-57.3-39.6-178.9-70.4-2.6000112.8Y434 S446 V472 K475 D477 Q484Y434-W442 HydrophobicContact CD1-CH2 4.02Å; Y434-W442 HydrophobicContact CD1-CZ2 4.34Å; Y434-W442 HydrophobicContact CD1-CZ3 4.4Å; Y434-W442 AromaticContact CD2-CE3 3.86Å; Y434-W442 HydrophobicContact CD2-CE3 3.86Å; Y434-W442 AromaticContact CD2-CH2 3.92Å; Y434-W442 HydrophobicContact CD2-CH2 3.92Å; Y434-W442 AromaticContact CD2-CZ3 3.46Å; Y434-W442 HydrophobicContact CD2-CZ3 3.46Å; Y434-W442 VanDerWaalsContact CD2-CZ3 3.46Å; Y434-W442 HydrophobicContact CE2-CH2 4.43Å; Y434-W442 HydrophobicContact CE2-CZ3 4.07Å; Y434-W442 HydrophobicContact CG-CD2 4.31Å; Y434-W442 AromaticContact CG-CE3 3.97Å; Y434-W442 HydrophobicContact CG-CE3 3.97Å; Y434-W442 AromaticContact CG-CH2 3.69Å; Y434-W442 HydrophobicContact CG-CH2 3.69Å; Y434-W442 HydrophobicContact CG-CZ2 4.09Å; Y434-W442 AromaticContact CG-CZ3 3.65Å; Y434-W442 HydrophobicContact CG-CZ3 3.65Å; Y434-W442 PolarHBondContact O-N 2.69Å; W442-S446 VanDerWaalsContact O-CB 3.31Å; W442-S446 WeakPolarHBondContact O-CB 3.4Å; W442-S446 PolarHBondContact O-N 2.81Å; W442-S446 VanDerWaalsContact O-N 3.16Å; W442-S446 PolarHBondContact O-OG 2.95Å; W442-V472 HydrophobicContact CB-CG1 4.4Å; W442-K475 HydrophobicContact CB-CD 3.68Å; W442-K475 HydrophobicContact CD2-CB 3.85Å; W442-K475 HydrophobicContact CD2-CD 3.79Å; W442-K475 HydrophobicContact CD2-CG 4.42Å; W442-K475 HydrophobicContact CE3-CB 3.65Å; W442-K475 HydrophobicContact CE3-CD 4.21Å; W442-K475 HydrophobicContact CG-CD 3.54Å; W442-K475 HydrophobicContact CH2-CB 4.28Å; W442-K475 HydrophobicContact CZ2-CB 4.42Å; W442-K475 HydrophobicContact CZ3-CB 3.88Å; W442-D477 HydrophobicContact CH2-CB 4.12Å; W442-Q484 HydrophobicContact CE3-CB 4.01Å; W442-Q484 HydrophobicContact CZ3-CB 4.19Å
443Y94.8Very high88.1Confident2 Ų240 Ų401%0.00820%0.2CC..Hα-helixtrans-69.4-51.4179.9177.8-115.7000112.3G424 A426 T441 Q445 S446 L447 V468 P486G424-Y443 WeakPolarHBondContact CA-OH 3.4Å; G424-Y443 PolarHBondContact O-OH 2.88Å; A426-Y443 HydrophobicContact CB-CD1 3.48Å; A426-Y443 VanDerWaalsContact CB-CD1 3.48Å; A426-Y443 HydrophobicContact CB-CE1 4.22Å; A426-Y443 HydrophobicContact CB-CG 3.65Å; T441-Y443 PolarHBondContact O-N 3.32Å; Y443-Q445 PolarHBondContact O-N 2.77Å; Y443-S446 PolarHBondContact O-N 2.67Å; Y443-L447 HydrophobicContact CE1-CD2 4.27Å; Y443-L447 WeakPolarHBondContact O-CB 3.42Å; Y443-L447 PolarHBondContact O-N 3.41Å; Y443-V468 HydrophobicContact CD2-CG1 3.72Å; Y443-V468 HydrophobicContact CE2-CG1 3.72Å; Y443-P486 HydrophobicContact CD2-CB 3.66Å; Y443-P486 HydrophobicContact CD2-CG 3.68Å; Y443-P486 HydrophobicContact CE2-CB 3.71Å; Y443-P486 HydrophobicContact CE2-CG 4.2Å
444I96.7Very high89.4Confident0 Ų043.4 Ų43.40%021%0.209CC..Hα-helixtrans-69-37.5-176.1-61.6-61.5000111.6D288 L292 L337 Q380 T441 L447 C448D288-I444 HydrophobicContact CB-CB 4.09Å; D288-I444 HydrophobicContact CB-CG1 4.42Å; D288-I444 HydrophobicContact CB-CG2 3.73Å; L292-I444 HydrophobicContact CD1-CD1 4.26Å; L292-I444 HydrophobicContact CD1-CG2 3.85Å; L292-I444 HydrophobicContact CD2-CD1 4.37Å; L292-I444 HydrophobicContact CD2-CG2 3.94Å; L292-I444 HydrophobicContact CG-CG2 3.59Å; L337-I444 HydrophobicContact CD2-CD1 4.07Å; L337-I444 HydrophobicContact CD2-CG1 3.93Å; Q380-I444 HydrophobicContact CB-CD1 3.97Å; Q380-I444 HydrophobicContact CB-CG1 3.8Å; Q380-I444 HydrophobicContact CG-CG1 3.83Å; T441-I444 PolarHBondContact O-N 2.84Å; T441-I444 WeakPolarHBondContact OG1-CB 3.43Å; T441-I444 WeakPolarHBondContact OG1-CG1 3.27Å; T441-I444 PolarHBondContact OG1-N 3.45Å; I444-L447 HydrophobicContact CD1-CD2 4.38Å; I444-L447 PolarHBondContact O-N 3.4Å; I444-C448 WeakPolarHBondContact O-CB 3.37Å; I444-C448 PolarHBondContact O-N 2.59Å; I444-C448 PolarHBondContact O-SG 3.27Å
445Q96.4Very high90.4Very high55 Ų5542.4 Ų42.426%0.25721%0.206SC..Hα-helixtrans-67.3-45177.1-63.1-57.9-4100111.7C287 D288 N439 T441 Y443 C448 Q449C287-Q445 PolarHBondContact O-NE2 3.42Å; D288-Q445 PolarHBondContact OD1-NE2 3.43Å; N439-Q445 VanDerWaalsContact O-CD 3.27Å; N439-Q445 WeakPolarHBondContact O-CG 3.32Å; T441-Q445 WeakPolarHBondContact O-CB 3.09Å; T441-Q445 VanDerWaalsContact O-CG 3.26Å; T441-Q445 WeakPolarHBondContact O-CG 3.3Å; T441-Q445 PolarHBondContact O-N 3.05Å; Y443-Q445 PolarHBondContact O-N 2.77Å; Q445-C448 PolarHBondContact O-N 2.88Å; Q445-Q449 WeakPolarHBondContact O-CB 3.25Å; Q445-Q449 PolarHBondContact O-N 3.4Å
446S96.5Very high91.1Very high1 Ų143 Ų431%0.00722%0.219CC..Hα-helixtrans-62.1-45.2172.6-81.50000111.6W442 Y443 C448 Q449 S450 D471 K475W442-S446 VanDerWaalsContact O-CB 3.31Å; W442-S446 WeakPolarHBondContact O-CB 3.4Å; W442-S446 PolarHBondContact O-N 2.81Å; W442-S446 VanDerWaalsContact O-N 3.16Å; W442-S446 PolarHBondContact O-OG 2.95Å; Y443-S446 PolarHBondContact O-N 2.67Å; S446-C448 PolarHBondContact O-N 3.05Å; S446-Q449 PolarHBondContact O-N 2.99Å; S446-S450 WeakPolarHBondContact O-CB 3.35Å; S446-S450 PolarHBondContact O-N 2.76Å; S446-S450 PolarHBondContact O-OG 2.6Å; S446-D471 WeakPolarHBondContact OG-CB 3.45Å; S446-K475 VanDerWaalsContact OG-CE 3.22Å; S446-K475 WeakPolarHBondContact OG-CE 3.34Å
447L97.4Very high91.9Very high0 Ų047.1 Ų47.10%024%0.237CC..Hα-helixtrans-56-50.5176.117863.8000112.4F378 Y443 I444 Q449 L451 L465 V468F378-L447 HydrophobicContact CB-CD2 4.38Å; F378-L447 HydrophobicContact CD1-CD2 3.6Å; F378-L447 HydrophobicContact CD2-CD2 4.22Å; F378-L447 HydrophobicContact CE1-CD1 4.08Å; F378-L447 HydrophobicContact CE1-CD2 3.83Å; F378-L447 HydrophobicContact CE2-CD2 4.42Å; F378-L447 HydrophobicContact CG-CD2 3.8Å; F378-L447 HydrophobicContact CZ-CD1 4.34Å; F378-L447 HydrophobicContact CZ-CD2 4.23Å; Y443-L447 HydrophobicContact CE1-CD2 4.27Å; Y443-L447 WeakPolarHBondContact O-CB 3.42Å; Y443-L447 PolarHBondContact O-N 3.41Å; I444-L447 HydrophobicContact CD1-CD2 4.38Å; I444-L447 PolarHBondContact O-N 3.4Å; L447-Q449 VanDerWaalsContact C-N 3.31Å; L447-Q449 PolarHBondContact O-N 2.91Å; L447-L451 HydrophobicContact CD1-CD1 3.83Å; L447-L451 HydrophobicContact CD1-CG 4.11Å; L447-L451 HydrophobicContact CG-CD1 3.88Å; L447-L451 VanDerWaalsContact O-CB 3.29Å; L447-L451 WeakPolarHBondContact O-CB 3.49Å; L447-L451 VanDerWaalsContact O-CG 3.24Å; L447-L451 WeakPolarHBondContact O-CG 3.21Å; L447-L451 PolarHBondContact O-N 3.36Å; L447-L465 HydrophobicContact CD1-CD2 3.82Å; L447-V468 HydrophobicContact CB-CG1 4.47Å; L447-V468 HydrophobicContact CB-CG2 4.35Å; L447-V468 HydrophobicContact CD1-CG2 4.2Å
448C97.8Very high92.9Very high0 Ų045.3 Ų45.30%023%0.233CC..Hα-helixtrans-66-32.5179-670000112.7A291 T295 I444 Q445 S446 R452A291-C448 VanDerWaalsContact C-SG 3.52Å; A291-C448 HydrophobicContact CB-CB 4.12Å; T295-C448 WeakPolarHBondContact OG1-CB 3.34Å; I444-C448 WeakPolarHBondContact O-CB 3.37Å; I444-C448 PolarHBondContact O-N 2.59Å; I444-C448 PolarHBondContact O-SG 3.27Å; Q445-C448 PolarHBondContact O-N 2.88Å; S446-C448 PolarHBondContact O-N 3.05Å; C448-R452 WeakPolarHBondContact O-CG 3.24Å; C448-R452 PolarHBondContact O-N 3.49Å; C448-R452 PolarHBondContact O-NE 2.95Å
449Q96.7Very high93.8Very high89 Ų8942 Ų4242%0.41621%0.212SC..Hα-helixtrans-68.8-57.9173.4-176.2175.8-4.100110.8Q445 S446 L447 L451 R452 E453Q445-Q449 WeakPolarHBondContact O-CB 3.25Å; Q445-Q449 PolarHBondContact O-N 3.4Å; S446-Q449 PolarHBondContact O-N 2.99Å; L447-Q449 VanDerWaalsContact C-N 3.31Å; L447-Q449 PolarHBondContact O-N 2.91Å; Q449-L451 VanDerWaalsContact C-N 3.3Å; Q449-L451 PolarHBondContact O-N 3.45Å; Q449-R452 PolarHBondContact O-N 3.24Å; Q449-R452 VanDerWaalsContact O-N 3.16Å; Q449-E453 HydrophobicContact CG-CG 4.41Å; Q449-E453 WeakPolarHBondContact CG-OE1 3.48Å; Q449-E453 PolarHBondContact NE2-OE1 2.94Å; Q449-E453 WeakPolarHBondContact O-CG 3.31Å; Q449-E453 PolarHBondContact O-N 2.85Å
450S96.6Very high94.7Very high1 Ų138.2 Ų38.21%0.00719%0.191CC..Hα-helixtrans-58.8-39.6-177.4-46.90000111.9S446 R454 V468 D471S446-S450 WeakPolarHBondContact O-CB 3.35Å; S446-S450 PolarHBondContact O-N 2.76Å; S446-S450 PolarHBondContact O-OG 2.6Å; S450-R454 WeakPolarHBondContact O-CB 3.44Å; S450-R454 WeakPolarHBondContact O-CG 3.26Å; S450-R454 PolarHBondContact O-N 3.48Å; S450-V468 WeakPolarHBondContact OG-CG2 3.38Å; S450-D471 PolarHBondContact OG-OD2 2.91Å
451L96.6Very high95.3Very high0 Ų038.2 Ų38.20%019%0.191CC..Hα-helixtrans-59.3-52.5174.4-78.5168.6000112.1T295 F296 L299 L447 Q449 E453 R454 C455 I461 I464 F498T295-L451 HydrophobicContact CG2-CB 3.8Å; T295-L451 HydrophobicContact CG2-CD1 3.97Å; F296-L451 HydrophobicContact CE1-CD1 4.05Å; F296-L451 HydrophobicContact CE2-CD1 4.39Å; F296-L451 HydrophobicContact CZ-CD1 3.66Å; L299-L451 HydrophobicContact CD1-CD2 4.44Å; L447-L451 HydrophobicContact CD1-CD1 3.83Å; L447-L451 HydrophobicContact CD1-CG 4.11Å; L447-L451 HydrophobicContact CG-CD1 3.88Å; L447-L451 VanDerWaalsContact O-CB 3.29Å; L447-L451 WeakPolarHBondContact O-CB 3.49Å; L447-L451 VanDerWaalsContact O-CG 3.24Å; L447-L451 WeakPolarHBondContact O-CG 3.21Å; L447-L451 PolarHBondContact O-N 3.36Å; Q449-L451 VanDerWaalsContact C-N 3.3Å; Q449-L451 PolarHBondContact O-N 3.45Å; L451-E453 VanDerWaalsContact C-N 3.31Å; L451-E453 PolarHBondContact O-N 2.81Å; L451-R454 PolarHBondContact O-N 2.99Å; L451-C455 WeakPolarHBondContact O-CB 3.27Å; L451-C455 PolarHBondContact O-N 3.16Å; L451-C455 PolarHBondContact O-SG 3.08Å; L451-I461 HydrophobicContact CD2-CD1 3.74Å; L451-I464 HydrophobicContact CD2-CD1 4.21Å; L451-I464 HydrophobicContact CD2-CG2 4.16Å; L451-I464 HydrophobicContact CG-CG2 4.27Å; L451-F498 HydrophobicContact CD2-CD2 4.36Å
452R95.8Very high95.7Very high86 Ų8640.3 Ų40.333%0.32520%0.201SC..Hα-helixtrans-66.3-32.6-177.6-71.4179.7-63.1-169.62.3113.1T295 E298 C448 Q449 P456T295-R452 HydrophobicContact CG2-CG 3.85Å; E298-R452 WeakPolarHBondContact OE2-CD 3.47Å; C448-R452 WeakPolarHBondContact O-CG 3.24Å; C448-R452 PolarHBondContact O-N 3.49Å; C448-R452 PolarHBondContact O-NE 2.95Å; Q449-R452 PolarHBondContact O-N 3.24Å; Q449-R452 VanDerWaalsContact O-N 3.16Å; R452-P456 VanDerWaalsContact O-CD 3.23Å; R452-P456 WeakPolarHBondContact O-CD 3.22Å; R452-P456 WeakPolarHBondContact O-CG 3.4Å
453E95.2Very high96Very high96 Ų9640.7 Ų40.745%0.44921%0.211SC..Hα-helixtrans-77.8-40.6178.4-70.4174.6-17400112.4Q449 L451 Q457Q449-E453 HydrophobicContact CG-CG 4.41Å; Q449-E453 WeakPolarHBondContact CG-OE1 3.48Å; Q449-E453 PolarHBondContact NE2-OE1 2.94Å; Q449-E453 WeakPolarHBondContact O-CG 3.31Å; Q449-E453 PolarHBondContact O-N 2.85Å; L451-E453 VanDerWaalsContact C-N 3.31Å; L451-E453 PolarHBondContact O-N 2.81Å; E453-Q457 PolarHBondContact O-NE2 3.45Å
454R95.4Very high96.1Very high90 Ų9040.6 Ų40.634%0.3421%0.211SC..Hα-helixtrans-101.5-28.4-167.6-64.1175168.7-95.53.4115.2S450 L451 P456 Q457 G458 D459 I464S450-R454 WeakPolarHBondContact O-CB 3.44Å; S450-R454 WeakPolarHBondContact O-CG 3.26Å; S450-R454 PolarHBondContact O-N 3.48Å; L451-R454 PolarHBondContact O-N 2.99Å; R454-P456 VanDerWaalsContact C-N 3.34Å; R454-Q457 WeakPolarHBondContact O-CA 3.39Å; R454-Q457 WeakPolarHBondContact O-CB 3.21Å; R454-Q457 PolarHBondContact O-N 2.77Å; R454-G458 PolarHBondContact O-N 3.44Å; R454-D459 HydrophobicContact CB-CB 3.92Å; R454-D459 WeakPolarHBondContact CB-OD2 3.12Å; R454-D459 VanDerWaalsContact CD-OD2 3.31Å; R454-D459 WeakPolarHBondContact CD-OD2 3.37Å; R454-D459 WeakPolarHBondContact CG-OD2 3.38Å; R454-D459 IonicContact CZ-OD2 2.67Å; R454-D459 IonicContact NE-OD2 2.85Å; R454-D459 IonicContact NH1-OD2 3.32Å; R454-D459 PolarHBondContact NH1-OD2 3.43Å; R454-D459 PolarHBondContact O-N 3.06Å; R454-I464 HydrophobicContact CB-CD1 4.04Å; R454-I464 HydrophobicContact CB-CG1 3.82Å
455C95Very high96.1Very high5 Ų540.6 Ų40.63%0.03421%0.211CC..G310 helixtrans-58.2-40173.6-69.30000112.9L299 L451 Q457 G458 I464L299-C455 HydrophobicContact CD2-CB 3.86Å; L451-C455 WeakPolarHBondContact O-CB 3.27Å; L451-C455 PolarHBondContact O-N 3.16Å; L451-C455 PolarHBondContact O-SG 3.08Å; C455-Q457 VanDerWaalsContact C-N 3.25Å; C455-Q457 PolarHBondContact O-N 3.21Å; C455-G458 PolarHBondContact O-N 3.44Å; C455-G458 VanDerWaalsContact O-N 3.15Å; C455-I464 WeakPolarHBondContact SG-CD1 3.21Å
456P93.9Very high96Very high82 Ų8242.4 Ų42.453%0.53223%0.226SC..G310 helixtrans-66.6-21.8172.6-22.935.6000114.7R452 R454 G458R452-P456 VanDerWaalsContact O-CD 3.23Å; R452-P456 WeakPolarHBondContact O-CD 3.22Å; R452-P456 WeakPolarHBondContact O-CG 3.4Å; R454-P456 VanDerWaalsContact C-N 3.34Å; P456-G458 VanDerWaalsContact C-N 3.31Å
457Q94.1Very high95.9Very high141 Ų14142.8 Ų42.866%0.65923%0.23SC*.G310 helixtrans-81.9-12.9175.2-61.5177.854.200112.3E453 R454 C455E453-Q457 PolarHBondContact O-NE2 3.45Å; R454-Q457 WeakPolarHBondContact O-CA 3.39Å; R454-Q457 WeakPolarHBondContact O-CB 3.21Å; R454-Q457 PolarHBondContact O-N 2.77Å; C455-Q457 VanDerWaalsContact C-N 3.25Å; C455-Q457 PolarHBondContact O-N 3.21Å
458G93.1Very high95.9Very high44 Ų4442.8 Ų42.845%0.45423%0.23SC..THydrogen-bonded Turntrans8820.1-17900000114.6R454 C455 P456 F497R454-G458 PolarHBondContact O-N 3.44Å; C455-G458 PolarHBondContact O-N 3.44Å; C455-G458 VanDerWaalsContact O-N 3.15Å; P456-G458 VanDerWaalsContact C-N 3.31Å; G458-F497 WeakPolarHBondContact O-CD1 3.35Å; G458-F497 WeakPolarHBondContact O-CE1 3Å
459D95.8Very high95.6Very high40 Ų4044.3 Ų44.321%0.21424%0.238CC..  trans-68.8143.4172.4-74.92.9000111.3R454 I464 F497R454-D459 HydrophobicContact CB-CB 3.92Å; R454-D459 WeakPolarHBondContact CB-OD2 3.12Å; R454-D459 VanDerWaalsContact CD-OD2 3.31Å; R454-D459 WeakPolarHBondContact CD-OD2 3.37Å; R454-D459 WeakPolarHBondContact CG-OD2 3.38Å; R454-D459 IonicContact CZ-OD2 2.67Å; R454-D459 IonicContact NE-OD2 2.85Å; R454-D459 IonicContact NH1-OD2 3.32Å; R454-D459 PolarHBondContact NH1-OD2 3.43Å; R454-D459 PolarHBondContact O-N 3.06Å; D459-I464 HydrophobicContact CB-CD1 4.1Å; D459-I464 HydrophobicContact CB-CG1 3.69Å; D459-F497 WeakPolarHBondContact O-CD1 3.24Å
460D96.8Very high95.3Very high21 Ų2147.4 Ų47.411%0.11225%0.247CC..  trans-79.5158.2171.183.890.9000111.6L462 S463 I464 L496 F497D460-L462 VanDerWaalsContact C-N 3.26Å; D460-L462 PolarHBondContact O-N 2.68Å; D460-L462 VanDerWaalsContact O-N 3.16Å; D460-L462 WeakPolarHBondContact OD1-CA 3.27Å; D460-L462 VanDerWaalsContact OD1-CB 3.31Å; D460-L462 WeakPolarHBondContact OD1-CB 3.38Å; D460-L462 PolarHBondContact OD1-N 2.62Å; D460-S463 WeakPolarHBondContact O-CB 3.5Å; D460-S463 PolarHBondContact O-N 2.76Å; D460-S463 VanDerWaalsContact O-N 3.13Å; D460-S463 PolarHBondContact OD1-N 3.27Å; D460-S463 VanDerWaalsContact OD2-CB 3.31Å; D460-S463 WeakPolarHBondContact OD2-CB 3.47Å; D460-S463 PolarHBondContact OD2-OG 3.42Å; D460-I464 WeakPolarHBondContact O-CG1 2.99Å; D460-I464 PolarHBondContact O-N 3.06Å; D460-L496 CarbonylContact C-O 3.51Å; D460-L496 WeakPolarHBondContact CA-O 3.48Å; D460-F497 HydrophobicContact CB-CD1 3.89Å; D460-F497 HydrophobicContact CB-CE1 3.55Å; D460-F497 HydrophobicContact CB-CZ 3.91Å
461I97.5Very high95.2Very high1 Ų150 Ų501%0.00526%0.261CS..Hα-helixtrans-59.3-30.3-174.5-164.351.2000114.6L422 L451 I464 L465 L492 L496 F498L422-I461 HydrophobicContact CD2-CB 4.31Å; L422-I461 HydrophobicContact CD2-CG1 3.59Å; L422-I461 HydrophobicContact CD2-CG2 3.69Å; L451-I461 HydrophobicContact CD2-CD1 3.74Å; I461-I464 HydrophobicContact CD1-CB 4.5Å; I461-L465 HydrophobicContact CD1-CD1 4.45Å; I461-L465 HydrophobicContact CD1-CG 4.39Å; I461-L465 HydrophobicContact CG1-CD1 4.02Å; I461-L465 HydrophobicContact CG1-CG 4.44Å; I461-L465 WeakPolarHBondContact O-CB 3.28Å; I461-L465 VanDerWaalsContact O-CG 3.24Å; I461-L465 WeakPolarHBondContact O-CG 3.5Å; I461-L465 PolarHBondContact O-N 3.38Å; I461-L492 HydrophobicContact CG2-CD1 4.12Å; I461-L496 HydrophobicContact CB-CG 4.49Å; I461-L496 HydrophobicContact CG2-CB 3.79Å; I461-L496 HydrophobicContact CG2-CD2 4.05Å; I461-L496 HydrophobicContact CG2-CG 4.11Å; I461-L496 PolarHBondContact N-O 3.26Å; I461-F498 HydrophobicContact CB-CE2 4.44Å; I461-F498 HydrophobicContact CD1-CE2 3.97Å; I461-F498 HydrophobicContact CG1-CE2 4.24Å
462L96.9Very high94.9Very high45 Ų4550 Ų5024%0.23626%0.261CS..Hα-helixtrans-76.5-38179.8-57.3179.4000110.4L422 D460 L465 T466 F490 L492L422-L462 HydrophobicContact CD1-CD2 3.97Å; D460-L462 VanDerWaalsContact C-N 3.26Å; D460-L462 PolarHBondContact O-N 2.68Å; D460-L462 VanDerWaalsContact O-N 3.16Å; D460-L462 WeakPolarHBondContact OD1-CA 3.27Å; D460-L462 VanDerWaalsContact OD1-CB 3.31Å; D460-L462 WeakPolarHBondContact OD1-CB 3.38Å; D460-L462 PolarHBondContact OD1-N 2.62Å; L462-L465 PolarHBondContact O-N 3.32Å; L462-T466 WeakPolarHBondContact O-CB 3.44Å; L462-T466 PolarHBondContact O-N 2.86Å; L462-T466 PolarHBondContact O-OG1 3.15Å; L462-F490 HydrophobicContact CD1-CD1 4.21Å; L462-F490 HydrophobicContact CD1-CD2 4.25Å; L462-F490 HydrophobicContact CD1-CE1 3.91Å; L462-F490 HydrophobicContact CD1-CE2 3.94Å; L462-F490 HydrophobicContact CD1-CG 4.38Å; L462-F490 HydrophobicContact CD1-CZ 3.77Å; L462-F490 HydrophobicContact CD2-CD1 3.71Å; L462-F490 HydrophobicContact CD2-CE1 4.05Å; L462-F490 HydrophobicContact CD2-CG 4.1Å; L462-L492 HydrophobicContact CD2-CD1 4.49Å
463S96.5Very high94.4Very high55 Ų5547.7 Ų47.739%0.38526%0.258SS..Hα-helixtrans-61-44.4169.1-63.40000111.4D460 T466 G467D460-S463 WeakPolarHBondContact O-CB 3.5Å; D460-S463 PolarHBondContact O-N 2.76Å; D460-S463 VanDerWaalsContact O-N 3.13Å; D460-S463 PolarHBondContact OD1-N 3.27Å; D460-S463 VanDerWaalsContact OD2-CB 3.31Å; D460-S463 WeakPolarHBondContact OD2-CB 3.47Å; D460-S463 PolarHBondContact OD2-OG 3.42Å; S463-T466 WeakPolarHBondContact O-CB 3.49Å; S463-T466 PolarHBondContact O-N 3.22Å; S463-G467 PolarHBondContact O-N 3.07Å; S463-G467 VanDerWaalsContact O-N 3.08Å
464I97.4Very high94Very high0 Ų047.4 Ų47.40%026%0.26CS..Hα-helixtrans-61.5-47.8175.5-63.7176.1000111L451 R454 C455 D459 D460 I461 T466 G467 V468L451-I464 HydrophobicContact CD2-CD1 4.21Å; L451-I464 HydrophobicContact CD2-CG2 4.16Å; L451-I464 HydrophobicContact CG-CG2 4.27Å; R454-I464 HydrophobicContact CB-CD1 4.04Å; R454-I464 HydrophobicContact CB-CG1 3.82Å; C455-I464 WeakPolarHBondContact SG-CD1 3.21Å; D459-I464 HydrophobicContact CB-CD1 4.1Å; D459-I464 HydrophobicContact CB-CG1 3.69Å; D460-I464 WeakPolarHBondContact O-CG1 2.99Å; D460-I464 PolarHBondContact O-N 3.06Å; I461-I464 HydrophobicContact CD1-CB 4.5Å; I464-T466 VanDerWaalsContact C-N 3.27Å; I464-T466 PolarHBondContact O-N 3.4Å; I464-G467 CarbonylContact O-C 3.43Å; I464-G467 WeakPolarHBondContact O-CA 3.33Å; I464-G467 PolarHBondContact O-N 2.88Å; I464-V468 WeakPolarHBondContact O-CG2 3.24Å; I464-V468 PolarHBondContact O-N 2.82Å
465L96.8Very high93.5Very high1 Ų146.4 Ų46.41%0.00526%0.258CS..Hα-helixtrans-66.3-27.7178.9-74.9167.8000113F378 L422 L447 I461 L462 V468 N469 P488F378-L465 HydrophobicContact CE1-CD2 4.21Å; L422-L465 HydrophobicContact CD1-CD1 3.97Å; L422-L465 HydrophobicContact CD2-CD1 3.94Å; L422-L465 HydrophobicContact CG-CD1 4.36Å; L447-L465 HydrophobicContact CD1-CD2 3.82Å; I461-L465 HydrophobicContact CD1-CD1 4.45Å; I461-L465 HydrophobicContact CD1-CG 4.39Å; I461-L465 HydrophobicContact CG1-CD1 4.02Å; I461-L465 HydrophobicContact CG1-CG 4.44Å; I461-L465 WeakPolarHBondContact O-CB 3.28Å; I461-L465 VanDerWaalsContact O-CG 3.24Å; I461-L465 WeakPolarHBondContact O-CG 3.5Å; I461-L465 PolarHBondContact O-N 3.38Å; L462-L465 PolarHBondContact O-N 3.32Å; L465-V468 PolarHBondContact O-N 3.05Å; L465-N469 WeakPolarHBondContact O-CB 3.4Å; L465-N469 PolarHBondContact O-N 3.42Å; L465-N469 PolarHBondContact O-OD1 3.38Å; L465-P488 HydrophobicContact CB-CG 4.43Å; L465-P488 HydrophobicContact CD1-CB 4.12Å
466T94.4Very high92.7Very high92 Ų9249.5 Ų49.556%0.56427%0.274SS*.Hα-helixtrans-67.8-37.3170.1-56.90000111.2L462 S463 I464 N469 Y470L462-T466 WeakPolarHBondContact O-CB 3.44Å; L462-T466 PolarHBondContact O-N 2.86Å; L462-T466 PolarHBondContact O-OG1 3.15Å; S463-T466 WeakPolarHBondContact O-CB 3.49Å; S463-T466 PolarHBondContact O-N 3.22Å; I464-T466 VanDerWaalsContact C-N 3.27Å; I464-T466 PolarHBondContact O-N 3.4Å; T466-N469 WeakPolarHBondContact O-CB 3.45Å; T466-N469 PolarHBondContact O-N 3.16Å; T466-Y470 PolarHBondContact O-N 3.04Å; T466-Y470 VanDerWaalsContact O-N 3.16Å
467G94.6Very high91.8Very high10 Ų1046.8 Ų46.810%0.10326%0.255CS..Hα-helixtrans-60.9-47167.900000112.6S463 I464 N469 Y470 D471S463-G467 PolarHBondContact O-N 3.07Å; S463-G467 VanDerWaalsContact O-N 3.08Å; I464-G467 CarbonylContact O-C 3.43Å; I464-G467 WeakPolarHBondContact O-CA 3.33Å; I464-G467 PolarHBondContact O-N 2.88Å; G467-N469 VanDerWaalsContact C-N 3.29Å; G467-N469 PolarHBondContact O-N 2.73Å; G467-Y470 WeakPolarHBondContact O-CB 3.47Å; G467-Y470 PolarHBondContact O-N 3.15Å; G467-Y470 VanDerWaalsContact O-N 3.11Å; G467-D471 PolarHBondContact O-N 3.09Å
468V96.2Very high90.9Very high0 Ų050.1 Ų50.10%026%0.262CS..Hα-helixtrans-59.7-40.1176.2178.20000111.6Y443 L447 S450 I464 L465 Y470 D471 V472Y443-V468 HydrophobicContact CD2-CG1 3.72Å; Y443-V468 HydrophobicContact CE2-CG1 3.72Å; L447-V468 HydrophobicContact CB-CG1 4.47Å; L447-V468 HydrophobicContact CB-CG2 4.35Å; L447-V468 HydrophobicContact CD1-CG2 4.2Å; S450-V468 WeakPolarHBondContact OG-CG2 3.38Å; I464-V468 WeakPolarHBondContact O-CG2 3.24Å; I464-V468 PolarHBondContact O-N 2.82Å; L465-V468 PolarHBondContact O-N 3.05Å; V468-Y470 VanDerWaalsContact C-N 3.34Å; V468-Y470 PolarHBondContact O-N 3.39Å; V468-D471 PolarHBondContact O-N 2.9Å; V468-V472 HydrophobicContact CG1-CG2 4.18Å; V468-V472 WeakPolarHBondContact O-CB 3.44Å; V468-V472 VanDerWaalsContact O-CG2 3.29Å; V468-V472 WeakPolarHBondContact O-CG2 3.4Å; V468-V472 PolarHBondContact O-N 3.12Å
469N91.8Very high89.9Confident31 Ų3159 Ų5917%0.16628%0.281CS..Hα-helixtrans-57.5-46.7174.5-82.41.5000111.4L465 T466 G467 S473 M485 P486L465-N469 WeakPolarHBondContact O-CB 3.4Å; L465-N469 PolarHBondContact O-N 3.42Å; L465-N469 PolarHBondContact O-OD1 3.38Å; T466-N469 WeakPolarHBondContact O-CB 3.45Å; T466-N469 PolarHBondContact O-N 3.16Å; G467-N469 VanDerWaalsContact C-N 3.29Å; G467-N469 PolarHBondContact O-N 2.73Å; N469-S473 WeakPolarHBondContact O-CB 3.35Å; N469-S473 PolarHBondContact O-N 3.4Å; N469-S473 PolarHBondContact O-OG 3.17Å; N469-M485 HydrophobicContact CB-CE 3.56Å; N469-P486 WeakPolarHBondContact OD1-CB 3.13Å; N469-P486 PolarHBondContact OD1-O 2.99Å
470Y91.8Very high88.7Confident155 Ų15561.7 Ų61.761%0.60830%0.296SS*.Hα-helixtrans-65.9-44.3176.4-179.1-94.5000112.6T466 G467 V468 V472 S473 N474T466-Y470 PolarHBondContact O-N 3.04Å; T466-Y470 VanDerWaalsContact O-N 3.16Å; G467-Y470 WeakPolarHBondContact O-CB 3.47Å; G467-Y470 PolarHBondContact O-N 3.15Å; G467-Y470 VanDerWaalsContact O-N 3.11Å; V468-Y470 VanDerWaalsContact C-N 3.34Å; V468-Y470 PolarHBondContact O-N 3.39Å; Y470-V472 VanDerWaalsContact C-N 3.34Å; Y470-V472 PolarHBondContact O-N 3.49Å; Y470-S473 PolarHBondContact O-N 2.92Å; Y470-S473 PolarHBondContact O-OG 3.31Å; Y470-S473 VanDerWaalsContact O-OG 3.08Å; Y470-N474 WeakPolarHBondContact CD1-ND2 3.44Å; Y470-N474 VanDerWaalsContact CE1-ND2 3.27Å; Y470-N474 WeakPolarHBondContact CE1-ND2 3.5Å; Y470-N474 VanDerWaalsContact CZ-ND2 3.31Å; Y470-N474 PolarHBondContact O-N 3.34Å; Y470-N474 VanDerWaalsContact O-N 3.12Å; Y470-N474 PolarHBondContact O-ND2 2.73Å
471D93.1Very high87.7Confident55 Ų5569.5 Ų69.529%0.29433%0.329SS..Hα-helixtrans-65.4-37.8-179-70.2-17.6000112.1S446 S450 G467 V468 K475S446-D471 WeakPolarHBondContact OG-CB 3.45Å; S450-D471 PolarHBondContact OG-OD2 2.91Å; G467-D471 PolarHBondContact O-N 3.09Å; V468-D471 PolarHBondContact O-N 2.9Å; D471-K475 WeakPolarHBondContact O-CE 3.5Å; D471-K475 WeakPolarHBondContact O-CG 3.35Å
472V89.8Confident86.5Confident0 Ų069.5 Ų69.50%033%0.329CS..Hα-helixtrans-79.1-37.9178.1179.50000111.5W442 V468 Y470 N474 K475 Q484 P486W442-V472 HydrophobicContact CB-CG1 4.4Å; V468-V472 HydrophobicContact CG1-CG2 4.18Å; V468-V472 WeakPolarHBondContact O-CB 3.44Å; V468-V472 VanDerWaalsContact O-CG2 3.29Å; V468-V472 WeakPolarHBondContact O-CG2 3.4Å; V468-V472 PolarHBondContact O-N 3.12Å; Y470-V472 VanDerWaalsContact C-N 3.34Å; Y470-V472 PolarHBondContact O-N 3.49Å; V472-N474 PolarHBondContact O-N 3.26Å; V472-K475 WeakPolarHBondContact O-CB 3.24Å; V472-K475 PolarHBondContact O-N 2.83Å; V472-Q484 HydrophobicContact CG1-CB 3.77Å; V472-Q484 HydrophobicContact CG1-CG 3.7Å; V472-P486 HydrophobicContact CB-CG 3.67Å; V472-P486 HydrophobicContact CG1-CG 3.71Å; V472-P486 HydrophobicContact CG2-CG 3.91Å
473S86.9Confident85.8Confident38 Ų3869.8 Ų69.827%0.26633%0.328SS..Hα-helixtrans-64.6-25.5176.674.70000112.5N469 Y470 K483N469-S473 WeakPolarHBondContact O-CB 3.35Å; N469-S473 PolarHBondContact O-N 3.4Å; N469-S473 PolarHBondContact O-OG 3.17Å; Y470-S473 PolarHBondContact O-N 2.92Å; Y470-S473 PolarHBondContact O-OG 3.31Å; Y470-S473 VanDerWaalsContact O-OG 3.08Å; S473-K483 WeakPolarHBondContact O-CE 3.32Å; S473-K483 PolarHBondContact O-NZ 3.05Å
474N85.2Confident85.1Confident89 Ų8967.3 Ų67.348%0.47631%0.31SS..Hα-helixtrans-76.2-22.6173-80.3-62000114.2Y470 V472 K483Y470-N474 WeakPolarHBondContact CD1-ND2 3.44Å; Y470-N474 VanDerWaalsContact CE1-ND2 3.27Å; Y470-N474 WeakPolarHBondContact CE1-ND2 3.5Å; Y470-N474 VanDerWaalsContact CZ-ND2 3.31Å; Y470-N474 PolarHBondContact O-N 3.34Å; Y470-N474 VanDerWaalsContact O-N 3.12Å; Y470-N474 PolarHBondContact O-ND2 2.73Å; V472-N474 PolarHBondContact O-N 3.26Å; N474-K483 PolarHBondContact O-NZ 2.9Å
475K85.4Confident84.8Confident69 Ų6970 Ų7030%0.332%0.324SS..  trans-71.9148.7177-63.2168.5-157.7-66.50111.3W442 S446 D471 V472 K483W442-K475 HydrophobicContact CB-CD 3.68Å; W442-K475 HydrophobicContact CD2-CB 3.85Å; W442-K475 HydrophobicContact CD2-CD 3.79Å; W442-K475 HydrophobicContact CD2-CG 4.42Å; W442-K475 HydrophobicContact CE3-CB 3.65Å; W442-K475 HydrophobicContact CE3-CD 4.21Å; W442-K475 HydrophobicContact CG-CD 3.54Å; W442-K475 HydrophobicContact CH2-CB 4.28Å; W442-K475 HydrophobicContact CZ2-CB 4.42Å; W442-K475 HydrophobicContact CZ3-CB 3.88Å; S446-K475 VanDerWaalsContact OG-CE 3.22Å; S446-K475 WeakPolarHBondContact OG-CE 3.34Å; D471-K475 WeakPolarHBondContact O-CE 3.5Å; D471-K475 WeakPolarHBondContact O-CG 3.35Å; V472-K475 WeakPolarHBondContact O-CB 3.24Å; V472-K475 PolarHBondContact O-N 2.83Å; K475-K483 WeakPolarHBondContact O-CE 3.49Å; K475-K483 PolarHBondContact O-NZ 3.43Å
476D79Confident84.5Confident71 Ų7170.2 Ų70.238%0.3833%0.325SS..  trans-140.4136.4-17775.6-68.6000112.9R478 K483D476-R478 PolarHBondContact O-N 3.31Å; D476-R478 IonicContact OD1-NE 3.95Å; D476-R478 WeakPolarHBondContact OD2-CG 3.45Å; D476-R478 IonicContact OD2-NE 3.65Å; D476-K483 HydrophobicContact CB-CD 4.23Å
477D74.9Confident84.3Confident25 Ų2569.5 Ų69.513%0.13432%0.315CS..BIsolated β-bridgetrans-89.194.3168.417414.2000108.7Y434 W442 R479 N480 K481 G482Y434-D477 HydrophobicContact CD1-CB 4.12Å; Y434-D477 HydrophobicContact CE1-CB 3.49Å; Y434-D477 VanDerWaalsContact CE1-CB 3.49Å; Y434-D477 WeakPolarHBondContact CE1-OD2 3.4Å; W442-D477 HydrophobicContact CH2-CB 4.12Å; D477-R479 PolarHBondContact O-N 3.43Å; D477-R479 WeakPolarHBondContact OD1-CB 3.41Å; D477-R479 PolarHBondContact OD1-N 3.03Å; D477-N480 PolarHBondContact O-N 2.8Å; D477-N480 WeakPolarHBondContact OD2-CB 3.38Å; D477-N480 PolarHBondContact OD2-ND2 3.31Å; D477-K481 VanDerWaalsContact O-CA 3.24Å; D477-K481 WeakPolarHBondContact O-CA 3.41Å; D477-K481 PolarHBondContact O-N 3.43Å; D477-G482 PolarHBondContact N-O 2.78Å; D477-G482 PolarHBondContact O-N 2.8Å
478R75.1Confident84.1Confident210 Ų21070.7 Ų70.779%0.79232%0.321SS*.THydrogen-bonded Turntrans-54.6-22.8178.1-66-178.7-176.7-176.61.8114.4D476D476-R478 PolarHBondContact O-N 3.31Å; D476-R478 IonicContact OD1-NE 3.95Å; D476-R478 WeakPolarHBondContact OD2-CG 3.45Å; D476-R478 IonicContact OD2-NE 3.65Å
479R71.9Confident83.8Confident230 Ų23074.3 Ų74.387%0.86834%0.343SS*.THydrogen-bonded Turntrans-78.8-45.6-178.8-61.7-178.9177.2176.61111.7D477D477-R479 PolarHBondContact O-N 3.43Å; D477-R479 WeakPolarHBondContact OD1-CB 3.41Å; D477-R479 PolarHBondContact OD1-N 3.03Å
480N71Confident83.9Confident97 Ų9778 Ų7852%0.51936%0.358SS..THydrogen-bonded Turntrans-103.92.7-177.7-58.1-64.8000113.5D477 G482D477-N480 PolarHBondContact O-N 2.8Å; D477-N480 WeakPolarHBondContact OD2-CB 3.38Å; D477-N480 PolarHBondContact OD2-ND2 3.31Å; N480-G482 PolarHBondContact O-N 2.7Å
481K74.3Confident83.6Confident186 Ų18673.5 Ų73.581%0.80935%0.347SS*.THydrogen-bonded Turntrans5332.7-169.1-58.8-177.2178.1-1780112.8D477D477-K481 VanDerWaalsContact O-CA 3.24Å; D477-K481 WeakPolarHBondContact O-CA 3.41Å; D477-K481 PolarHBondContact O-N 3.43Å
482G73.1Confident83.6Confident0 Ų071.9 Ų71.90%034%0.338CS..BIsolated β-bridgetrans-89.8146.2-17300000112.9Y434 D477 N480Y434-G482 WeakPolarHBondContact OH-CA 3.48Å; D477-G482 PolarHBondContact N-O 2.78Å; D477-G482 PolarHBondContact O-N 2.8Å; N480-G482 PolarHBondContact O-N 2.7Å
483K82.3Confident83.7Confident52 Ų5277.1 Ų77.123%0.22636%0.358CS..BIsolated β-bridgetrans-116163.6173-58-65.4-71.6174.60109.8Q388 S473 N474 K475 D476Q388-K483 HydrophobicContact CB-CB 4.44Å; Q388-K483 WeakPolarHBondContact CB-O 3.32Å; Q388-K483 PolarHBondContact O-N 3.22Å; S473-K483 WeakPolarHBondContact O-CE 3.32Å; S473-K483 PolarHBondContact O-NZ 3.05Å; N474-K483 PolarHBondContact O-NZ 2.9Å; K475-K483 WeakPolarHBondContact O-CE 3.49Å; K475-K483 PolarHBondContact O-NZ 3.43Å; D476-K483 HydrophobicContact CB-CD 4.23Å
484Q81.3Confident84.1Confident2 Ų279.3 Ų79.31%0.00936%0.363CS..  trans-128.8141.1171.5-176.6173.4-19.900108.7A426 Y434 W442 V472A426-Q484 PolarHBondContact O-NE2 2.93Å; Y434-Q484 HydrophobicContact CD2-CB 3.95Å; Y434-Q484 HydrophobicContact CE2-CB 4.32Å; W442-Q484 HydrophobicContact CE3-CB 4.01Å; W442-Q484 HydrophobicContact CZ3-CB 4.19Å; V472-Q484 HydrophobicContact CG1-CB 3.77Å; V472-Q484 HydrophobicContact CG1-CG 3.7Å
485M92.4Very high84.6Confident58 Ų5878.9 Ų78.929%0.28636%0.357SS..  trans-134.6103.2178.7-170.666.6-118.400107.9T427 V428 N469T427-M485 CarbonylContact C-O 3.48Å; T427-M485 VanDerWaalsContact CA-O 3.27Å; T427-M485 WeakPolarHBondContact CA-O 3.33Å; V428-M485 HydrophobicContact CG1-CB 4.21Å; V428-M485 HydrophobicContact CG1-CG 4.23Å; V428-M485 PolarHBondContact N-O 3.08Å; N469-M485 HydrophobicContact CB-CE 3.56Å
486P89.9Confident85.2Confident4 Ų475.6 Ų75.63%0.02634%0.343CS..  trans-65.5157.7173.9-1528.7000111.2M425 A426 Y443 N469 V472M425-P486 WeakPolarHBondContact O-CA 3.04Å; M425-P486 WeakPolarHBondContact O-CB 3.25Å; A426-P486 WeakPolarHBondContact O-CA 3.43Å; Y443-P486 HydrophobicContact CD2-CB 3.66Å; Y443-P486 HydrophobicContact CD2-CG 3.68Å; Y443-P486 HydrophobicContact CE2-CB 3.71Å; Y443-P486 HydrophobicContact CE2-CG 4.2Å; N469-P486 WeakPolarHBondContact OD1-CB 3.13Å; N469-P486 PolarHBondContact OD1-O 2.99Å; V472-P486 HydrophobicContact CB-CG 3.67Å; V472-P486 HydrophobicContact CG1-CG 3.71Å; V472-P486 HydrophobicContact CG2-CG 3.91Å
487Q89.4Confident86.1Confident77 Ų7774.9 Ų74.936%0.3634%0.336SS..EExtended strand (participates in β ladder)trans-141.8100-176.7-174179.7-9.400110.4M425 V428M425-Q487 VanDerWaalsContact CB-O 3.31Å; M425-Q487 WeakPolarHBondContact CB-O 3.48Å; M425-Q487 PolarHBondContact N-O 3.03Å; M425-Q487 VanDerWaalsContact N-O 3.17Å; M425-Q487 PolarHBondContact O-N 3.22Å; V428-Q487 HydrophobicContact CG1-CB 4.11Å
488P91.3Very high87Confident35 Ų3573.9 Ų73.923%0.22733%0.331CS..EExtended strand (participates in β ladder)trans-74.7146.1167.531.6-33.4000111.3L422 L423 L465L422-P488 HydrophobicContact CD1-CB 4.45Å; L423-P488 CarbonylContact O-C 3.58Å; L423-P488 WeakPolarHBondContact O-CA 3.13Å; L465-P488 HydrophobicContact CB-CG 4.43Å; L465-P488 HydrophobicContact CD1-CB 4.12Å
489T88.9Confident87.7Confident76 Ų7666.6 Ų66.647%0.46631%0.311SS..EExtended strand (participates in β ladder)trans-133.4140.3169.6-58.30000108L423L423-T489 PolarHBondContact N-O 2.79Å; L423-T489 PolarHBondContact O-N 3.11Å
490F93.9Very high87.9Confident108 Ų10860.4 Ų60.447%0.47430%0.3SS..EExtended strand (participates in β ladder)trans-147.6152.2-174.563.2-90.3000114.3F421 L422 L462 L492F421-F490 CarbonylContact O-C 3.43Å; F421-F490 WeakPolarHBondContact O-CA 3.29Å; L422-F490 HydrophobicContact CD1-CB 3.88Å; L462-F490 HydrophobicContact CD1-CD1 4.21Å; L462-F490 HydrophobicContact CD1-CD2 4.25Å; L462-F490 HydrophobicContact CD1-CE1 3.91Å; L462-F490 HydrophobicContact CD1-CE2 3.94Å; L462-F490 HydrophobicContact CD1-CG 4.38Å; L462-F490 HydrophobicContact CD1-CZ 3.77Å; L462-F490 HydrophobicContact CD2-CD1 3.71Å; L462-F490 HydrophobicContact CD2-CE1 4.05Å; L462-F490 HydrophobicContact CD2-CG 4.1Å; F490-L492 HydrophobicContact CB-CG 4.17Å; F490-L492 HydrophobicContact CD2-CB 4.21Å
491T86.8Confident88.7Confident62 Ų6258.6 Ų58.638%0.3829%0.289SS..  trans-121.322.716762.70000110.8E418 D420 F421E418-T491 WeakPolarHBondContact O-CB 3.24Å; E418-T491 PolarHBondContact O-OG1 2.72Å; D420-T491 PolarHBondContact N-O 2.87Å; D420-T491 PolarHBondContact N-OG1 2.94Å; F421-T491 PolarHBondContact N-OG1 3.37Å; F421-T491 PolarHBondContact O-N 3.37Å
492L92.9Very high89.5Confident21 Ų2151.8 Ų51.811%0.1126%0.262CS..  trans-60.4133174.5-63.1-178.1000111Y248 P374 F421 L422 I461 L462 F490 L496Y248-L492 HydrophobicContact CE2-CB 4.22Å; Y248-L492 HydrophobicContact CE2-CD2 3.84Å; Y248-L492 HydrophobicContact CE2-CG 4.46Å; Y248-L492 WeakPolarHBondContact OH-CA 3.47Å; P374-L492 HydrophobicContact CB-CD2 4.28Å; F421-L492 PolarHBondContact O-N 2.91Å; L422-L492 HydrophobicContact CB-CD1 4.14Å; L422-L492 HydrophobicContact CB-CD2 4.3Å; L422-L492 HydrophobicContact CB-CG 4.22Å; L422-L492 HydrophobicContact CD2-CD1 4.27Å; I461-L492 HydrophobicContact CG2-CD1 4.12Å; L462-L492 HydrophobicContact CD2-CD1 4.49Å; F490-L492 HydrophobicContact CB-CG 4.17Å; F490-L492 HydrophobicContact CD2-CB 4.21Å; L492-L496 HydrophobicContact CD1-CB 4.29Å; L492-L496 HydrophobicContact CD1-CD2 4.21Å; L492-L496 HydrophobicContact CD2-CD2 4.47Å
493R92.3Very high90.4Very high109 Ų10954.7 Ų54.741%0.41128%0.276SS..  trans-106.82.5-177.8-58178.4-63.1144.3-1.7113.7Y248 I415 D420Y248-R493 PolarHBondContact OH-N 3.35Å; I415-R493 VanDerWaalsContact CD1-NH2 3.35Å; D420-R493 IonicContact OD1-CZ 2.89Å; D420-R493 IonicContact OD1-NE 3.43Å; D420-R493 PolarHBondContact OD1-NE 3.48Å; D420-R493 IonicContact OD1-NH2 2.69Å; D420-R493 PolarHBondContact OD1-NH2 3.27Å; D420-R493 IonicContact OD2-CZ 3.37Å; D420-R493 IonicContact OD2-NE 3.38Å; D420-R493 IonicContact OD2-NH2 2.92Å; D420-R493 PolarHBondContact OD2-NH2 3.21Å
494K93.9Very high90.9Very high84 Ų8454.9 Ų54.937%0.36528%0.279SS..SBendtrans-149.3155-175.4-62-173.3-171.5172.40109.1K246 V247 Y248K246-K494 HydrophobicContact CB-CB 4.49Å; K246-K494 HydrophobicContact CB-CD 4.34Å; K246-K494 HydrophobicContact CB-CG 3.92Å; K246-K494 CarbonylContact O-C 3.52Å; K246-K494 WeakPolarHBondContact O-CA 3.48Å; K246-K494 WeakPolarHBondContact O-CB 3.37Å; V247-K494 WeakPolarHBondContact O-CD 3.38Å; Y248-K494 HydrophobicContact CD1-CB 4.16Å; Y248-K494 HydrophobicContact CD1-CD 3.95Å; Y248-K494 HydrophobicContact CD1-CG 4.43Å; Y248-K494 HydrophobicContact CD2-CB 3.65Å; Y248-K494 HydrophobicContact CE1-CB 4.12Å; Y248-K494 HydrophobicContact CE1-CD 4.16Å; Y248-K494 HydrophobicContact CE1-CG 4.28Å; Y248-K494 HydrophobicContact CE2-CB 3.63Å; Y248-K494 WeakPolarHBondContact CE2-O 3.3Å; Y248-K494 HydrophobicContact CG-CB 3.93Å; Y248-K494 HydrophobicContact CG-CD 4.31Å
495K96.9Very high91.5Very high80 Ų8058.2 Ų58.235%0.34830%0.296SS..BIsolated β-bridgetrans-64.1140.8168.9-69.2-170.3177176.10109.8D245 K246 V247 Y248 F497D245-K495 HydrophobicContact CB-CD 3.88Å; D245-K495 HydrophobicContact CB-CG 4.37Å; D245-K495 VanDerWaalsContact CG-CE 3.45Å; D245-K495 VanDerWaalsContact CG-NZ 3.32Å; D245-K495 IonicContact OD1-NZ 2.91Å; D245-K495 VanDerWaalsContact OD2-CE 3.31Å; D245-K495 WeakPolarHBondContact OD2-CE 3.46Å; D245-K495 IonicContact OD2-NZ 2.73Å; D245-K495 PolarHBondContact OD2-NZ 2.8Å; K246-K495 PolarHBondContact O-N 3.38Å; V247-K495 WeakPolarHBondContact CA-O 3.49Å; Y248-K495 PolarHBondContact N-O 3.27Å; K495-F497 HydrophobicContact CB-CD2 4.3Å; K495-F497 HydrophobicContact CB-CE2 3.49Å; K495-F497 VanDerWaalsContact CB-CE2 3.49Å; K495-F497 HydrophobicContact CB-CZ 3.94Å; K495-F497 HydrophobicContact CD-CE2 4.28Å; K495-F497 HydrophobicContact CD-CZ 3.96Å
496L97.5Very high91.4Very high1 Ų158.2 Ų58.21%0.00530%0.297CS..  trans-120.5112.5-176.4179.754.4000109.9Y248 M250 P374 I376 D460 I461 L492 F498Y248-L496 HydrophobicContact CD2-CB 3.88Å; Y248-L496 HydrophobicContact CD2-CD1 3.99Å; Y248-L496 HydrophobicContact CD2-CG 4.42Å; Y248-L496 HydrophobicContact CE2-CB 4.37Å; Y248-L496 HydrophobicContact CG-CD1 4.39Å; M250-L496 HydrophobicContact CE-CD1 3.37Å; P374-L496 HydrophobicContact CB-CD1 4.04Å; P374-L496 HydrophobicContact CB-CD2 3.57Å; P374-L496 HydrophobicContact CB-CG 4.46Å; P374-L496 HydrophobicContact CG-CD1 3.77Å; P374-L496 HydrophobicContact CG-CD2 4.22Å; I376-L496 HydrophobicContact CD1-CD2 3.69Å; I376-L496 HydrophobicContact CG1-CD2 4.38Å; D460-L496 CarbonylContact C-O 3.51Å; D460-L496 WeakPolarHBondContact CA-O 3.48Å; I461-L496 HydrophobicContact CB-CG 4.49Å; I461-L496 HydrophobicContact CG2-CB 3.79Å; I461-L496 HydrophobicContact CG2-CD2 4.05Å; I461-L496 HydrophobicContact CG2-CG 4.11Å; I461-L496 PolarHBondContact N-O 3.26Å; L492-L496 HydrophobicContact CD1-CB 4.29Å; L492-L496 HydrophobicContact CD1-CD2 4.21Å; L492-L496 HydrophobicContact CD2-CD2 4.47Å; L496-F498 HydrophobicContact CD1-CE1 4.13Å; L496-F498 HydrophobicContact CD1-CZ 4.26Å; L496-F498 HydrophobicContact CD2-CZ 4.05Å; L496-F498 HydrophobicContact CG-CE1 4.38Å; L496-F498 HydrophobicContact CG-CZ 4.01Å
497F97.1Very high91.5Very high55 Ų5562.1 Ų62.124%0.24132%0.316CS..  trans-117.3149.9177.1-54.4-90.9000109.7V247 M250 G458 D459 D460 K495 P499V247-F497 HydrophobicContact CG1-CD2 3.59Å; V247-F497 HydrophobicContact CG1-CE2 3.93Å; V247-F497 HydrophobicContact CG2-CD2 4.39Å; V247-F497 HydrophobicContact CG2-CE2 3.88Å; M250-F497 WeakPolarHBondContact CG-O 3.44Å; G458-F497 WeakPolarHBondContact O-CD1 3.35Å; G458-F497 WeakPolarHBondContact O-CE1 3Å; D459-F497 WeakPolarHBondContact O-CD1 3.24Å; D460-F497 HydrophobicContact CB-CD1 3.89Å; D460-F497 HydrophobicContact CB-CE1 3.55Å; D460-F497 HydrophobicContact CB-CZ 3.91Å; K495-F497 HydrophobicContact CB-CD2 4.3Å; K495-F497 HydrophobicContact CB-CE2 3.49Å; K495-F497 VanDerWaalsContact CB-CE2 3.49Å; K495-F497 HydrophobicContact CB-CZ 3.94Å; K495-F497 HydrophobicContact CD-CE2 4.28Å; K495-F497 HydrophobicContact CD-CZ 3.96Å; F497-P499 VanDerWaalsContact O-CD 3.26Å; F497-P499 WeakPolarHBondContact O-CD 3.38Å
498F95.1Very high91.7Very high5 Ų560.9 Ų60.92%0.02231%0.313CS..  trans-112.482.7170.4-58.5-62.3000109.8M250 L299 F301 I376 L451 I461 L496M250-F498 HydrophobicContact CE-CD1 4.11Å; M250-F498 HydrophobicContact CE-CE1 3.82Å; M250-F498 HydrophobicContact CG-CD1 4.22Å; M250-F498 HydrophobicContact SD-CD1 4.04Å; M250-F498 HydrophobicContact SD-CE1 4.17Å; L299-F498 HydrophobicContact CD1-CB 4.08Å; L299-F498 HydrophobicContact CD1-CD2 4.36Å; L299-F498 HydrophobicContact CD1-CG 4.34Å; L299-F498 HydrophobicContact CD2-CB 3.98Å; L299-F498 HydrophobicContact CG-CB 4.43Å; F301-F498 AromaticContact CE2-CD1 3.94Å; F301-F498 HydrophobicContact CE2-CD1 3.94Å; F301-F498 HydrophobicContact CE2-CE1 4.1Å; F301-F498 HydrophobicContact CZ-CD1 4.02Å; F301-F498 AromaticContact CZ-CE1 3.76Å; F301-F498 HydrophobicContact CZ-CE1 3.76Å; I376-F498 HydrophobicContact CD1-CE1 4.4Å; I376-F498 HydrophobicContact CD1-CE2 4.43Å; I376-F498 HydrophobicContact CD1-CZ 3.56Å; L451-F498 HydrophobicContact CD2-CD2 4.36Å; I461-F498 HydrophobicContact CB-CE2 4.44Å; I461-F498 HydrophobicContact CD1-CE2 3.97Å; I461-F498 HydrophobicContact CG1-CE2 4.24Å; L496-F498 HydrophobicContact CD1-CE1 4.13Å; L496-F498 HydrophobicContact CD1-CZ 4.26Å; L496-F498 HydrophobicContact CD2-CZ 4.05Å; L496-F498 HydrophobicContact CG-CE1 4.38Å; L496-F498 HydrophobicContact CG-CZ 4.01Å
499P89.9Confident91.7Very high57 Ų5763.1 Ų63.137%0.3732%0.32SS..  trans-65136.2175.627.4-33.6000110.1M250 R255 F497M250-P499 HydrophobicContact CB-CG 4.36Å; M250-P499 HydrophobicContact CG-CG 4.48Å; R255-P499 PolarHBondContact NH2-O 3.04Å; F497-P499 VanDerWaalsContact O-CD 3.26Å; F497-P499 WeakPolarHBondContact O-CD 3.38Å
500P75.5Confident92Very high99 Ų9961.9 Ų61.964%0.64331%0.306SS*.  trans-71.50-17730.8-36.7000114.5H300H300-P500 PolarHBondContact NE2-OXT 2.98Å; H300-P500 VanDerWaalsContact NE2-OXT 3.09Å

Retrieved 500 of 500 residues in 760 ms (Link to these results)