A0A087WS65_MOUSE Loading...

Thyroid hormone receptor interactor 12

AlphaFold DB , UniProt , Accession A0A087WS65, Species MOUSE (Mus musculus, Mouse), Gene Trip12, Length 65 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M66.2Low67.1Low233 Ų233125.1 Ų125.1100%1.14869%0.69SS**  0121.10-63.3167.2-163.200107.1
2S69.8Low66.4Low109 Ų109121.3 Ų121.376%0.76268%0.679SS**  trans-88.8107.6-172.2-66.10000111.4R4S2-R4 PolarHBondContact O-N 3.19Å
3N72.1Confident66Low154 Ų154119.6 Ų119.682%0.82467%0.667SS**  trans-88.449.7174.5-70.413.3000111.6P5N3-P5 WeakPolarHBondContact O-CD 3.41Å
4R77.6Confident66Low217 Ų217125.4 Ų125.482%0.81967%0.673SS**  trans-82.3120.8177.1-79.6-177.4-178.7156.70.5109.6S2 N6S2-R4 PolarHBondContact O-N 3.19Å; R4-N6 PolarHBondContact O-N 3.24Å
5P71.6Confident65.7Low105 Ų105128.1 Ų128.168%0.68267%0.67SS**  trans-64.1122.5174.125.1-31.1000109.5N3 N7N3-P5 WeakPolarHBondContact O-CD 3.41Å; P5-N7 VanDerWaalsContact C-N 3.31Å; P5-N7 PolarHBondContact O-N 2.99Å
6N69.4Low65.4Low146 Ų146126.9 Ų126.978%0.78168%0.676SS**  trans-75.583174.9175.319.1000109.5R4R4-N6 PolarHBondContact O-N 3.24Å
7N67.2Low65.5Low137 Ų137127.4 Ų127.473%0.73367%0.673SS**  trans-91.3101.7165.2-71.2-52.7000107P5 P9P5-N7 VanDerWaalsContact C-N 3.31Å; P5-N7 PolarHBondContact O-N 2.99Å; N7-P9 WeakPolarHBondContact O-CD 3.19Å
8N62.7Low65.7Low117 Ų117130.6 Ų130.663%0.62668%0.675SS**  trans-89.195.4170.9-174.56.1000108.7G10N8-G10 PolarHBondContact O-N 3.35Å; N8-G10 PolarHBondContact OD1-N 3.2Å
9P57.4Low65.6Low108 Ų108131.8 Ų131.870%0.70168%0.682SS**THydrogen-bonded Turntrans-76.6-6.1-174.933.3-27.3000111.5N7N7-P9 WeakPolarHBondContact O-CD 3.19Å
10G62.9Low65.3Low31 Ų31130.6 Ų130.632%0.3268%0.681SS.*THydrogen-bonded Turntrans-82.2-8.7-176.500000115.2N8 R14N8-G10 PolarHBondContact O-N 3.35Å; N8-G10 PolarHBondContact OD1-N 3.2Å; G10-R14 WeakPolarHBondContact O-CD 3.39Å; G10-R14 WeakPolarHBondContact O-CG 3.5Å
11G61.1Low65Low19 Ų19128.9 Ų128.920%0.19669%0.686CS.*THydrogen-bonded Turntrans-94.5-36-168.200000115.9R15G11-R15 PolarHBondContact O-NH1 3.17Å; G11-R15 PolarHBondContact O-NH2 3.13Å
12S58.3Low64.6Low80 Ų80121 Ų12156%0.55967%0.665SS**THydrogen-bonded Turntrans-89.9-35.4-176.749.50000112.4S16S12-S16 WeakPolarHBondContact O-CB 3.44Å; S12-S16 PolarHBondContact O-N 3.39Å; S12-S16 VanDerWaalsContact O-N 3.08Å; S12-S16 PolarHBondContact O-OG 3.23Å; S12-S16 VanDerWaalsContact O-OG 3.09Å
13L61.4Low64Low99 Ų99119.2 Ų119.252%0.51866%0.657SS.*Hα-helixtrans-71.1-44.6-176.4-163.965.1000112.2R15 Q17L13-R15 VanDerWaalsContact C-N 3.3Å; L13-R15 PolarHBondContact O-N 3.09Å; L13-Q17 HydrophobicContact CD1-CG 4.26Å; L13-Q17 VanDerWaalsContact CD1-NE2 3.31Å; L13-Q17 HydrophobicContact CG-CG 4.49Å; L13-Q17 VanDerWaalsContact O-CB 3.29Å; L13-Q17 WeakPolarHBondContact O-CB 3.27Å; L13-Q17 VanDerWaalsContact O-CG 3.27Å; L13-Q17 WeakPolarHBondContact O-CG 3.29Å; L13-Q17 PolarHBondContact O-N 3.08Å; L13-Q17 VanDerWaalsContact O-N 3.13Å
14R65.8Low63.1Low200 Ų200119.4 Ų119.476%0.75565%0.652SS**Hα-helixtrans-64.7-32-179.6-67.1-177-177.5-98.71.5113.1G10G10-R14 WeakPolarHBondContact O-CD 3.39Å; G10-R14 WeakPolarHBondContact O-CG 3.5Å
15R61.8Low62.3Low167 Ų167113.8 Ų113.863%0.6364%0.644SS**Hα-helixtrans-82.5-43.7178.6-74.1-165.6-65.8-90.90.7112.4G11 L13 Q17 R18G11-R15 PolarHBondContact O-NH1 3.17Å; G11-R15 PolarHBondContact O-NH2 3.13Å; L13-R15 VanDerWaalsContact C-N 3.3Å; L13-R15 PolarHBondContact O-N 3.09Å; R15-Q17 PolarHBondContact O-N 3.33Å; R15-R18 PolarHBondContact O-N 3.42Å
16S61.6Low61.5Low109 Ų109117.3 Ų117.376%0.76265%0.651SS**Hα-helixtrans-71.1-14.2-179.8-58.20000113.7S12S12-S16 WeakPolarHBondContact O-CB 3.44Å; S12-S16 PolarHBondContact O-N 3.39Å; S12-S16 VanDerWaalsContact O-N 3.08Å; S12-S16 PolarHBondContact O-OG 3.23Å; S12-S16 VanDerWaalsContact O-OG 3.09Å
17Q66.6Low60.5Low135 Ų135116.5 Ų116.563%0.63165%0.647SS**THydrogen-bonded Turntrans-103.75.4178.5-67.1-177-2000114.8L13 R15 N19L13-Q17 HydrophobicContact CD1-CG 4.26Å; L13-Q17 VanDerWaalsContact CD1-NE2 3.31Å; L13-Q17 HydrophobicContact CG-CG 4.49Å; L13-Q17 VanDerWaalsContact O-CB 3.29Å; L13-Q17 WeakPolarHBondContact O-CB 3.27Å; L13-Q17 VanDerWaalsContact O-CG 3.27Å; L13-Q17 WeakPolarHBondContact O-CG 3.29Å; L13-Q17 PolarHBondContact O-N 3.08Å; L13-Q17 VanDerWaalsContact O-N 3.13Å; R15-Q17 PolarHBondContact O-N 3.33Å; Q17-N19 VanDerWaalsContact C-N 3.33Å; Q17-N19 PolarHBondContact O-N 3.42Å
18R68.9Low59.7Low185 Ų185117.6 Ų117.670%0.69865%0.653SS**  trans-73.193.9169.6-86.1-171.1-69.8158.80.9109R15R15-R18 PolarHBondContact O-N 3.42Å
19N64.9Low59Low153 Ų153116.9 Ų116.982%0.81866%0.657SS**  trans-75.5114.2152.7-117.9-47.2000106.5Q17 A21Q17-N19 VanDerWaalsContact C-N 3.33Å; Q17-N19 PolarHBondContact O-N 3.42Å; N19-A21 PolarHBondContact O-N 3.29Å
20T58.2Low58.7Low107 Ų107119.6 Ų119.666%0.65666%0.664SS**  trans-75.868.1168-53.80000108.1G22 A23T20-G22 PolarHBondContact O-N 2.63Å; T20-A23 HydrophobicContact CG2-CB 3.35Å
21A59.5Low58.1Low96 Ų96121.3 Ų121.379%0.79368%0.682SS**THydrogen-bonded Turntrans-81.598.3169.100000107.1N19N19-A21 PolarHBondContact O-N 3.29Å
22G58.4Low57.5Low67 Ų67123.8 Ų123.869%0.69171%0.708SS**THydrogen-bonded Turntrans96.441.5-178.900000114.7T20 Q24T20-G22 PolarHBondContact O-N 2.63Å; G22-Q24 PolarHBondContact O-N 2.68Å
23A56.9Low57.8Low72 Ų72132 Ų13260%0.59573%0.726SS**  trans-60.796.3144.600000105T20T20-A23 HydrophobicContact CG2-CB 3.35Å
24Q53.7Low57Low158 Ų158132.6 Ų132.674%0.73874%0.739SS**  trans-43130.1158-61.5-107.9-109.900104.9G22 Q26G22-Q24 PolarHBondContact O-N 2.68Å; Q24-Q26 PolarHBondContact O-N 2.87Å
25P59.4Low56.4Low98 Ų98129.2 Ų129.264%0.63674%0.744SS**  trans-47.7119.3159.221.6-28.1000103.6D27P25-D27 PolarHBondContact O-N 3.02Å
26Q54.5Low56Low180 Ų180126.5 Ų126.584%0.84175%0.751SS**  trans-64.389.8170.2-71.8-175.5-89.900102.4Q24 D28Q24-Q26 PolarHBondContact O-N 2.87Å; Q26-D28 PolarHBondContact O-N 3.28Å
27D48.8Very low55.7Low129 Ų129127.1 Ų127.169%0.6976%0.755SS**  trans-49.1118.4161.3-74.2-68.5000103.4P25 S29P25-D27 PolarHBondContact O-N 3.02Å; D27-S29 PolarHBondContact O-N 2.82Å
28D51.7Low54.8Low159 Ų159126.3 Ų126.385%0.8576%0.764SS**SBendtrans-63.465.8-179.5-73.2-66000109.8Q26Q26-D28 PolarHBondContact O-N 3.28Å
29S47.9Very low54.3Low103 Ų103123.6 Ų123.672%0.7277%0.774SS**  trans-116.376.8171.4-66.40000105.2D27 G31D27-S29 PolarHBondContact O-N 2.82Å; S29-G31 PolarHBondContact O-N 2.88Å
30I51Low54Low164 Ų164119.8 Ų119.884%0.84176%0.764SS**  trans-32.2120.2159.3-61.8-67.7000108.8
31G49.3Very low53.9Low68 Ų68121.1 Ų121.170%0.70177%0.772SS**SBendtrans62.693.6152.100000115.9S29S29-G31 PolarHBondContact O-N 2.88Å
32G47.8Very low54Low71 Ų71123.5 Ų123.573%0.73277%0.769SS**  trans68.8118.5133.400000117.5
33R64.7Low54.2Low251 Ų251125.6 Ų125.695%0.94777%0.769SS**  trans57.598.1146.7-57177169-145.9-3.7115.6
34S44.8Very low54.5Low112 Ų112127.4 Ų127.478%0.78377%0.774SS**  trans-152.9114.2132.3-161.80000110.4S36S34-S36 PolarHBondContact O-N 2.93Å
35C54Low54.4Low130 Ų130127.8 Ų127.888%0.87878%0.776SS**  trans-66.5118.3161.5-58.30000107.9
36S53.1Low54.5Low110 Ų110129.2 Ų129.277%0.76979%0.785SS**  trans-155.5115.8157.7-78.30000109.2S34S34-S36 PolarHBondContact O-N 2.93Å
37S54.7Low55.1Low122 Ų122128.4 Ų128.485%0.85378%0.781SS**  trans-41.7136.1175.5-71.80000113.3
38S47.7Very low55.6Low117 Ų117127.2 Ų127.282%0.81878%0.775SS**  trans-142.9113.7148.1-830000108.4A40S38-A40 PolarHBondContact O-N 3.01Å
39S59.1Low55.9Low128 Ų128125 Ų12590%0.89577%0.769SS**  trans-63.596.217855.50000110.2
40A58.4Low56.2Low74 Ų74127 Ų12761%0.61277%0.772SS**  trans-108.6110.6164.100000107.5S38 I42S38-A40 PolarHBondContact O-N 3.01Å; A40-I42 PolarHBondContact O-N 3.32Å
41V55.8Low56.5Low135 Ų135129.3 Ų129.382%0.81877%0.77SS**  trans-58.2103.8167.3171.20000106.9V43V41-V43 HydrophobicContact CG1-CG2 4.21Å; V41-V43 PolarHBondContact O-N 2.95Å; V41-V43 VanDerWaalsContact O-N 3.09Å
42I61.6Low56.9Low146 Ų146130.4 Ų130.475%0.74977%0.772SS**  trans-75.298172.8-56.6-71.7000106.4A40 P44A40-I42 PolarHBondContact O-N 3.32Å; I42-P44 WeakPolarHBondContact O-CD 3.45Å
43V62.8Low57.4Low111 Ų111133 Ų13367%0.67377%0.77SS**  trans-71.2120.7163179.20000106.5V41 Q45V41-V43 HydrophobicContact CG1-CG2 4.21Å; V41-V43 PolarHBondContact O-N 2.95Å; V41-V43 VanDerWaalsContact O-N 3.09Å; V43-Q45 PolarHBondContact O-N 3.39Å
44P63.8Low57Low109 Ų109127.7 Ų127.771%0.70877%0.765SS**  trans-64.8112.917324.7-29.1000107.8I42I42-P44 WeakPolarHBondContact O-CD 3.45Å
45Q51.1Low57.8Low167 Ų167128.5 Ų128.578%0.7877%0.77SS**PPolyproline II helixtrans-65131171.3-66.5-170.918.100107.9V43 E47V43-Q45 PolarHBondContact O-N 3.39Å; Q45-E47 PolarHBondContact O-N 3.09Å
46P62Low58.1Low127 Ų127129 Ų12983%0.82576%0.76SS**PPolyproline II helixtrans-63120.5177.723.9-30.3000109.1D48P46-D48 PolarHBondContact O-N 3.06Å
47E67.9Low58.5Low164 Ų164133.1 Ų133.177%0.76676%0.759SS**PPolyproline II helixtrans-64.5132.1-179.6-65.9122.8119.200111.2Q45Q45-E47 PolarHBondContact O-N 3.09Å
48D59.2Low58.9Low104 Ų104136.9 Ų136.956%0.55676%0.763SS**PPolyproline II helixtrans-65.9127.9-178.3-168.5-55.1000111.4P46 D50 R51P46-D48 PolarHBondContact O-N 3.06Å; D48-D50 PolarHBondContact O-N 3.18Å; D48-D50 VanDerWaalsContact O-N 3.15Å; D48-D50 WeakPolarHBondContact OD1-CB 3.36Å; D48-D50 PolarHBondContact OD1-N 3.38Å; D48-R51 PolarHBondContact O-N 3.18Å
49P57.3Low59.6Low111 Ų111140 Ų14072%0.72176%0.761SS**G310 helixtrans-63.9-14.5-177.825.8-33.5000114.3R51 A52P49-R51 PolarHBondContact O-N 3.48Å; P49-A52 WeakPolarHBondContact O-CB 3.47Å; P49-A52 PolarHBondContact O-N 3.33Å
50D54.9Low59.5Low146 Ų146140.4 Ų140.478%0.78176%0.759SS**G310 helixtrans-75.5-6.1176.5-74.9-59.7000113.6D48 A52D48-D50 PolarHBondContact O-N 3.18Å; D48-D50 VanDerWaalsContact O-N 3.15Å; D48-D50 WeakPolarHBondContact OD1-CB 3.36Å; D48-D50 PolarHBondContact OD1-N 3.38Å; D50-A52 PolarHBondContact O-N 3.21Å
51R55.5Low59.8Low213 Ų213140 Ų14080%0.80476%0.762SS**G310 helixtrans-72.6-9.7171.7-162.2175174.2-168.7-1.2112.9D48 P49 N53D48-R51 PolarHBondContact O-N 3.18Å; P49-R51 PolarHBondContact O-N 3.48Å; R51-N53 VanDerWaalsContact C-N 3.29Å; R51-N53 PolarHBondContact O-N 3.15Å
52A57.8Low59.9Low91 Ų91141.8 Ų141.875%0.75276%0.762SS**SBendtrans-86.240.2-176.200000113.8P49 D50P49-A52 WeakPolarHBondContact O-CB 3.47Å; P49-A52 PolarHBondContact O-N 3.33Å; D50-A52 PolarHBondContact O-N 3.21Å
53N58.2Low59.7Low126 Ų126141.5 Ų141.567%0.67477%0.766SS**  trans-155.594169.5-158.3-37.7000114.1R51R51-N53 VanDerWaalsContact C-N 3.29Å; R51-N53 PolarHBondContact O-N 3.15Å
54T58.1Low59.6Low139 Ų139141.8 Ų141.885%0.85377%0.77SS**  trans-139.913.2156.1660000114E56T54-E56 PolarHBondContact O-N 3.29Å
55S60Low59.2Low128 Ų128150 Ų15090%0.89580%0.795SS**  trans-98.161.7177.4-700000111
56E60.9Low59.6Low140 Ų140149.1 Ų149.165%0.65480%0.795SS**  trans-114.7122.7162.5-155.5-140.7128.400110.3T54T54-E56 PolarHBondContact O-N 3.29Å
57R61.5Low59.5Low197 Ų197150.3 Ų150.374%0.74379%0.794SS**  trans66.385171.2-71.7178.5-168.7-102-3.1118
58Q62.6Low59.1Low201 Ų201149.5 Ų149.594%0.93980%0.795SS**  trans-91.186.6134.9-68.6-165-48.600109.4
59K63.6Low59.1Low182 Ų182152.2 Ų152.279%0.79181%0.809SS**  trans-120.178159.5-170.1157-172.6-90.50109.1G61K59-G61 PolarHBondContact O-N 2.89Å
60T57.3Low59.2Low137 Ų137154.8 Ų154.884%0.8482%0.815SS**  trans-8984.3164.3-52.80000108
61G64.3Low59.4Low66 Ų66155.3 Ų155.368%0.6882%0.817SS**  trans-99.986.8160.200000108.3K59K59-G61 PolarHBondContact O-N 2.89Å
62Q57.2Low59.7Low173 Ų173151.2 Ų151.281%0.80882%0.818SS**  trans-126.7105.8163.2-81.1-131.38800108.1
63V56.7Low59.9Low139 Ų139155.8 Ų155.884%0.84282%0.823SS**  trans-82.8121165.71780000106.8
64P61Low60Low117 Ų117158.3 Ų158.376%0.7684%0.836SS**  trans-81.4129.6176.1-8.125.7000111.7
65K57.1Low60.2Low281 Ų281160.1 Ų160.1100%1.22283%0.834SS**  trans37.70161.8-60.9-169.1-177.2-178.70119.2

Retrieved 65 of 65 residues in 23.1 ms (Link to these results)