A0A087WS78_MOUSE Loading...

Phosphoinositide kinase, FYVE type zinc finger containing

AlphaFold DB , UniProt , Accession A0A087WS78, Species MOUSE (Mus musculus, Mouse), Gene Pikfyve, Length 66 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M51.8Low54.2Low254 Ų254137.6 Ų137.6100%1.25179%0.79SS**  0149.60-73.5-174.3167.700108.3
2A47.8Very low54Low88 Ų88137.3 Ų137.373%0.72778%0.784SS**  trans-85.5153.2-158.100000115.2
3T52.4Low53.7Low122 Ų122134.8 Ų134.875%0.74878%0.78SS**  trans32.7115.6146.2550000119.2
4D56.1Low53.6Low128 Ų128132.9 Ų132.968%0.68479%0.788SS**  trans-118.689.6148.6-168.4-129.8000107.7K6D4-K6 VanDerWaalsContact O-N 3.14Å; D4-K6 PolarHBondContact O-N 2.75Å; D4-K6 WeakPolarHBondContact OD1-CG 3.32Å; D4-K6 WeakPolarHBondContact OD1-CE 3.16Å
5D57.7Low53.8Low134 Ų134134.5 Ų134.572%0.71779%0.791SS**  trans-69.591.2163.1-88.4-60.4000108S7D5-S7 PolarHBondContact O-N 3Å
6K57.2Low54Low185 Ų185135.4 Ų135.480%0.80479%0.792SS**  trans-78.566.3160.3-86.1-178.8-1751650110.2D4 S8D4-K6 VanDerWaalsContact O-N 3.14Å; D4-K6 PolarHBondContact O-N 2.75Å; D4-K6 WeakPolarHBondContact OD1-CG 3.32Å; D4-K6 WeakPolarHBondContact OD1-CE 3.16Å; K6-S8 PolarHBondContact O-N 3.42Å
7S55.6Low54.4Low94 Ų94136.4 Ų136.466%0.65779%0.792SS**  trans-66.8120.1150.655.60000108.3D5D5-S7 PolarHBondContact O-N 3Å
8S52.9Low54.3Low94 Ų94135.9 Ų135.966%0.65779%0.794SS**  trans146.9104.3139.5-63.60000110.2K6 T10K6-S8 PolarHBondContact O-N 3.42Å; S8-T10 PolarHBondContact O-N 2.79Å
9P55.7Low54.6Low124 Ų124140.9 Ų140.981%0.80580%0.798SS**  trans-66.4113150.428.2-28.4000107L11P9-L11 VanDerWaalsContact C-N 3.27Å; P9-L11 PolarHBondContact O-N 2.73Å
10T53.9Low54.7Low129 Ų129138.8 Ų138.879%0.79179%0.793SS**  trans-63.292.4168.234.60000108.6S8 D12S8-T10 PolarHBondContact O-N 2.79Å; T10-D12 PolarHBondContact O-N 2.79Å; T10-D12 VanDerWaalsContact O-N 3.1Å
11L54.8Low55Low162 Ų162138.2 Ų138.285%0.84879%0.794SS**  trans-80.768.1173-159.3173.3000107.6P9P9-L11 VanDerWaalsContact C-N 3.27Å; P9-L11 PolarHBondContact O-N 2.73Å
12D51.7Low55.1Low133 Ų133130.3 Ų130.371%0.71177%0.769SS**  trans-130.6108179.4-102.4-63.4000111.9T10T10-D12 PolarHBondContact O-N 2.79Å; T10-D12 VanDerWaalsContact O-N 3.1Å
13S51Low55.6Low106 Ų106131.4 Ų131.474%0.74177%0.771SS**  trans74.345.2135.1-61.70000118.4
14A51.7Low56Low108 Ų108129.9 Ų129.989%0.89376%0.764SS**  trans-103.828.1154.200000112.5
15N56.3Low56.3Low156 Ų156128.5 Ų128.583%0.83476%0.764SS**  trans-107.313.1-174.3-148.225.4000114.3
16D58.2Low56.6Low150 Ų150128 Ų12880%0.80276%0.757SS**  trans-106.735.6-174.3-135.7-72.6000114.3
17L59.3Low56.8Low151 Ų151127 Ų12779%0.79176%0.76SS**SBendtrans-122.4126.4153.2-89.386.2000106.9R19L17-R19 PolarHBondContact O-N 2.53Å
18P53.8Low57.4Low128 Ų128127.2 Ų127.283%0.83176%0.757SS**  trans-60.895.6160.725.7-29.5000106.1S20P18-S20 PolarHBondContact O-N 3.17Å
19R59.8Low58Low232 Ų232128.9 Ų128.988%0.87575%0.754SS**  trans-43.4118.8169.8-170.289.7-177.6150.92.5105.1L17L17-R19 PolarHBondContact O-N 2.53Å
20S57.5Low58.5Low98 Ų98131.6 Ų131.669%0.68575%0.754SS**  trans-27.6128.7179.5-50.40000110.3P18 A22P18-S20 PolarHBondContact O-N 3.17Å; S20-A22 PolarHBondContact O-N 2.79Å
21P59.1Low59Low126 Ų126134.6 Ų134.682%0.81876%0.756SS**  trans-50.6111.9-17321.4-31.9000106.5S23P21-S23 PolarHBondContact O-N 3.11Å
22A55.9Low59.4Low89 Ų89132 Ų13274%0.73675%0.749SS**  trans-50.4118.2-177.500000105.2S20 P24S20-A22 PolarHBondContact O-N 2.79Å; A22-P24 WeakPolarHBondContact O-CA 3.5Å
23S57.2Low59.9Low110 Ų110134 Ų13477%0.76976%0.758SS**  trans-38.7117.3177.4-66.30000106.9P21 S25P21-S23 PolarHBondContact O-N 3.11Å; S23-S25 PolarHBondContact O-N 2.97Å
24P60.5Low60.6Low91 Ų91134.1 Ų134.159%0.59176%0.755SS**  trans-58.6121.8-16523.1-32.5000106.1A22 H26A22-P24 WeakPolarHBondContact O-CA 3.5Å; P24-H26 PolarHBondContact O-N 2.79Å; P24-H26 VanDerWaalsContact O-CD2 3.3Å; P24-H26 PolarHBondContact O-CD2 2.71Å; P24-H26 WeakPolarHBondContact CG-NE2 3.36Å; P24-H26 VanDerWaalsContact CG-NE2 3.31Å
25S62.7Low61Low98 Ų98133.4 Ų133.469%0.68574%0.741SS**  trans-6781.5-178.5-175.90000107.8S23 L27S23-S25 PolarHBondContact O-N 2.97Å; S25-L27 PolarHBondContact O-N 2.77Å
26H64.3Low61Low125 Ų125132.4 Ų132.458%0.57974%0.736SS**G310 helixtrans-70.513.1-178.6-76-169.7000112.4P24 H29P24-H26 PolarHBondContact O-N 2.79Å; P24-H26 VanDerWaalsContact O-CD2 3.3Å; P24-H26 PolarHBondContact O-CD2 2.71Å; P24-H26 WeakPolarHBondContact CG-NE2 3.36Å; P24-H26 VanDerWaalsContact CG-NE2 3.31Å; H26-H29 AromaticContact CD2-CE1 3.73Å; H26-H29 AromaticContact CD2-NE2 3.04Å; H26-H29 PolarHBondContact CD2-NE2 3.06Å; H26-H29 AromaticContact CE1-NE2 3.91Å; H26-H29 AromaticContact CG-CD2 3.99Å; H26-H29 AromaticContact CG-NE2 3.22Å; H26-H29 AromaticContact ND1-NE2 3.76Å; H26-H29 AromaticContact NE2-CE1 3.98Å; H26-H29 AromaticContact NE2-NE2 3.53Å
27L62.3Low61Low164 Ų164132.3 Ų132.386%0.85973%0.73SS**G310 helixtrans-87.1-4.2175.3-108.2110.4000114.2S25S25-L27 PolarHBondContact O-N 2.77Å
28T66.4Low61Low97 Ų97132.6 Ų132.660%0.59573%0.733SS**G310 helixtrans-136.253.9171.9610000111.2F30T28-F30 PolarHBondContact O-N 3.3Å
29H66.4Low61.2Low130 Ų130131.4 Ų131.460%0.60272%0.716SS**  trans-68.775.7155-70.1-73.2000108.1H26 K31H26-H29 AromaticContact CD2-CE1 3.73Å; H26-H29 AromaticContact CD2-NE2 3.04Å; H26-H29 PolarHBondContact CD2-NE2 3.06Å; H26-H29 AromaticContact CE1-NE2 3.91Å; H26-H29 AromaticContact CG-CD2 3.99Å; H26-H29 AromaticContact CG-NE2 3.22Å; H26-H29 AromaticContact ND1-NE2 3.76Å; H26-H29 AromaticContact NE2-CE1 3.98Å; H26-H29 AromaticContact NE2-NE2 3.53Å; H29-K31 VanDerWaalsContact C-N 3.32Å; H29-K31 PolarHBondContact O-N 3.04Å
30F66.2Low61.2Low181 Ų181123.2 Ų123.279%0.79469%0.693SS**  trans-54.1109.7150.9-83.3-87.7000105.1T28 P32T28-F30 PolarHBondContact O-N 3.3Å; F30-P32 VanDerWaalsContact O-N 3.15Å; F30-P32 WeakPolarHBondContact O-CD 3.45Å
31K64.6Low61.2Low192 Ų192122.9 Ų122.984%0.83569%0.689SS**  trans-52.2123.2171-77.6173.5175.4173.90106.4H29 L33H29-K31 VanDerWaalsContact C-N 3.32Å; H29-K31 PolarHBondContact O-N 3.04Å; K31-L33 PolarHBondContact O-N 2.96Å; K31-L33 VanDerWaalsContact O-N 3.11Å
32P63.8Low60.9Low108 Ų108124 Ų12470%0.70168%0.681SS**  trans-52.5124.4171.6-21.731.4000107.3F30 T34 P35F30-P32 VanDerWaalsContact O-N 3.15Å; F30-P32 WeakPolarHBondContact O-CD 3.45Å; P32-T34 PolarHBondContact O-N 2.7Å; P32-P35 WeakPolarHBondContact O-CD 3.4Å
33L61.3Low61Low173 Ų173127.1 Ų127.191%0.90668%0.678SS**SBendtrans-72.672.4175-84162.3000109K31K31-L33 PolarHBondContact O-N 2.96Å; K31-L33 VanDerWaalsContact O-N 3.11Å
34T64.7Low61Low110 Ų110126.4 Ų126.468%0.67567%0.673SS**  trans167.683.2146.731.60000107.4P32 D36P32-T34 PolarHBondContact O-N 2.7Å; T34-D36 VanDerWaalsContact C-N 3.33Å; T34-D36 PolarHBondContact O-N 3.1Å
35P60.3Low60.9Low92 Ų92125.8 Ų125.860%0.59768%0.675SS**  -62116.1123.99.58.1000103.4P32 Q37P32-P35 WeakPolarHBondContact O-CD 3.4Å; P35-Q37 VanDerWaalsContact C-N 3.29Å; P35-Q37 PolarHBondContact O-N 2.85Å
36D57.7Low60.6Low136 Ų136131.9 Ų131.973%0.72769%0.685SS**  trans-40.8111.6156-83.5-72.1000106.2T34 D38T34-D36 VanDerWaalsContact C-N 3.33Å; T34-D36 PolarHBondContact O-N 3.1Å; D36-D38 PolarHBondContact O-N 2.95Å
37Q57.2Low60.2Low147 Ų147131.2 Ų131.269%0.68769%0.694SS**  trans-69.183167-67.7-105.6-51.900102.8P35 E39P35-Q37 VanDerWaalsContact C-N 3.29Å; P35-Q37 PolarHBondContact O-N 2.85Å; Q37-E39 PolarHBondContact O-N 3.25Å
38D59.4Low60.1Low157 Ų157126.7 Ų126.784%0.8468%0.676SS**SBendtrans-50.188.4148.9-99.6-66.8000104.7D36D36-D38 PolarHBondContact O-N 2.95Å
39E57.5Low59.7Low104 Ų104130.3 Ų130.349%0.48668%0.684SS.*  trans25.6120.2-174.4-77.4-172.4109.400115.4Q37 F42Q37-E39 PolarHBondContact O-N 3.25Å; E39-F42 HydrophobicContact CB-CD2 3.86Å; E39-F42 HydrophobicContact CB-CE2 4.41Å; E39-F42 HydrophobicContact CG-CD2 3.64Å; E39-F42 HydrophobicContact CG-CE2 4.12Å; E39-F42 VanDerWaalsContact OE1-CD2 3.32Å; E39-F42 WeakPolarHBondContact OE1-CD2 3.5Å
40P59.8Low59.6Low59 Ų59130.8 Ų130.838%0.38370%0.696SS.*SBendtrans-48.6129.6148.325.9-32.5000104.7F42P40-F42 PolarHBondContact O-N 2.78Å; P40-F42 HydrophobicContact CG-CE1 4.47Å; P40-F42 WeakPolarHBondContact O-CD2 3.5Å; P40-F42 WeakPolarHBondContact O-CA 3.38Å; P40-F42 HydrophobicContact CG-CZ 3.87Å; P40-F42 HydrophobicContact CG-CE2 3.62Å; P40-F42 HydrophobicContact CG-CD2 4.01Å
41P57.9Low59.6Low92 Ų92127.3 Ų127.360%0.59769%0.686SS**  trans-57.497.2-17015.3-26.4000107.7K43 S44P41-K43 PolarHBondContact O-N 3.48Å; P41-S44 WeakPolarHBondContact CB-OG 3.31Å; P41-S44 PolarHBondContact O-N 2.96Å
42F53.5Low59.7Low150 Ų150124.8 Ų124.866%0.65868%0.681SS**THydrogen-bonded Turntrans-68.89.7-179.6-83-78.3000109.1E39 P40E39-F42 HydrophobicContact CB-CD2 3.86Å; E39-F42 HydrophobicContact CB-CE2 4.41Å; E39-F42 HydrophobicContact CG-CD2 3.64Å; E39-F42 HydrophobicContact CG-CE2 4.12Å; E39-F42 VanDerWaalsContact OE1-CD2 3.32Å; E39-F42 WeakPolarHBondContact OE1-CD2 3.5Å; P40-F42 PolarHBondContact O-N 2.78Å; P40-F42 HydrophobicContact CG-CE1 4.47Å; P40-F42 WeakPolarHBondContact O-CD2 3.5Å; P40-F42 WeakPolarHBondContact O-CA 3.38Å; P40-F42 HydrophobicContact CG-CZ 3.87Å; P40-F42 HydrophobicContact CG-CE2 3.62Å; P40-F42 HydrophobicContact CG-CD2 4.01Å
43K57.6Low60Low154 Ų154128.2 Ų128.267%0.6768%0.684SS**THydrogen-bonded Turntrans-125.3-7.1-169.9-56.4-177.2-169.8-69.40112.7P41P41-K43 PolarHBondContact O-N 3.48Å
44S56.2Low60.3Low95 Ų95130.6 Ų130.666%0.66468%0.682SS**SBendtrans-91.9-21.2-170.4-67.40000116.8P41P41-S44 WeakPolarHBondContact CB-OG 3.31Å; P41-S44 PolarHBondContact O-N 2.96Å
45A58.4Low60.2Low77 Ų77133.1 Ų133.164%0.63668%0.684SS**SBendtrans-141.4-22-175.800000116.2
46Y56.6Low60Low226 Ų226135.2 Ų135.289%0.88669%0.689SS**THydrogen-bonded Turntrans-96.96-179.6-89.3-87.2000114.2S48Y46-S48 VanDerWaalsContact C-N 3.3Å
47S55.7Low60.2Low112 Ų112136.9 Ų136.978%0.78369%0.69SS**THydrogen-bonded Turntrans-86.3-2.3170.6-178.40000112.8
48S60.2Low60.3Low68 Ų68136.4 Ų136.448%0.47669%0.692SS.*SBendtrans-112.4129.6174.8-172.20000108.2Y46Y46-S48 VanDerWaalsContact C-N 3.3Å
49F59.3Low60.2Low173 Ų173138.2 Ų138.276%0.75970%0.696SS**SBendtrans102.529.3168.9-46.9-63.1000121.1
50V64.8Low60.4Low140 Ų140136.4 Ų136.485%0.84871%0.705SS**SBendtrans-146.3102.5150.3-87.80000107.3
51N64.6Low60Low109 Ų109139.6 Ų139.658%0.58373%0.725SS**  -16097.669.5-164.865.8000110.3F53N51-F53 VanDerWaalsContact C-N 3.3Å; N51-F53 PolarHBondContact ND2-O 2.93Å
52L68Low60.1Low139 Ų139144 Ų14473%0.72874%0.736SS**SBendtrans-85.40.3-179.9-92.263.7000114
53F70.2Confident60.2Low179 Ų179145.1 Ų145.179%0.78574%0.741SS**  trans-138.4108.2172.2-56.7-79.4000108.5N51N51-F53 VanDerWaalsContact C-N 3.3Å; N51-F53 PolarHBondContact ND2-O 2.93Å
54R67.1Low60.2Low224 Ų224141.7 Ų141.785%0.84575%0.749SS**  trans-10675.1159.3-167.414666.2166.51.9108.3
55F63.5Low60.3Low163 Ų163144.9 Ų144.972%0.71576%0.758SS**  trans-89.9105.9167.1-165.5-94.2000108.6K57F55-K57 HydrophobicContact CD1-CB 4.44Å; F55-K57 HydrophobicContact CE1-CB 3.84Å; F55-K57 HydrophobicContact CE1-CD 4.32Å; F55-K57 HydrophobicContact CE1-CG 4.32Å; F55-K57 HydrophobicContact CZ-CB 4.44Å
56N55.9Low60Low135 Ų135148.6 Ų148.672%0.72280%0.803SS**  trans-138.479.5159.1-78.5-41.9000108.1D58N56-D58 PolarHBondContact O-N 3.14Å
57K60Low60.2Low172 Ų172144.7 Ų144.775%0.74880%0.799SS**  trans20.7-5.9131.6-160.5166165.3-178.50123F55F55-K57 HydrophobicContact CD1-CB 4.44Å; F55-K57 HydrophobicContact CE1-CB 3.84Å; F55-K57 HydrophobicContact CE1-CD 4.32Å; F55-K57 HydrophobicContact CE1-CG 4.32Å; F55-K57 HydrophobicContact CZ-CB 4.44Å
58D59.3Low60.4Low136 Ų136146.4 Ų146.473%0.72780%0.8SS**  trans-124.238.9-167-63-58.8000114.6N56N56-D58 PolarHBondContact O-N 3.14Å
59Q58.1Low60.4Low196 Ų196150.8 Ų150.892%0.91682%0.818SS**  trans-122.273.1159.7-79.4-174.87.300110.3
60G61.7Low60.5Low65 Ų65149.5 Ų149.567%0.6782%0.821SS**  trans-77.6150.8135.800000108.2
61P50.9Low60.2Low126 Ų126150.1 Ų150.182%0.81882%0.82SS**  -133.3128.874.125.7-5.9000111.6
62F59.7Low59.9Low186 Ų186152.8 Ų152.882%0.81684%0.835SS**  87.7102.392.4-155.4-90.2000111.2
63F57.5Low59.3Low173 Ų173153.8 Ų153.876%0.75984%0.843SS**  trans22.8111.2152.9-75.3-93.2000118.4L65F63-L65 HydrophobicContact CD1-CD1 4.4Å
64G56Low58.5Low82 Ų82151.8 Ų151.885%0.84585%0.847SS**  trans-139.167157.500000109.6
65L58.8Low57.8Low162 Ų162145.8 Ų145.885%0.84885%0.848SS**  trans-70.8128.9157.4-74.4163.6000107.2F63F63-L65 HydrophobicContact CD1-CD1 4.4Å
66G52.1Low57.3Low154 Ų154144.3 Ų144.3100%1.58886%0.86SS**  trans174.50176.600000110.7

Retrieved 66 of 66 residues in 13 ms (Link to these results)