A0A087WTJ4_HUMAN Loading...

Trehalase

AlphaFold DB , UniProt , Accession A0A087WTJ4, Species HUMAN (Homo sapiens, Human), Gene TREH, Length 37 aa.

						>A0A087WTJ4_HUMAN|A0A087WTJ4|TREH
MPGRTWELCLLLLLGLGLGSQEALPPPCERTSPADLH
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	57.9	Low	80.9	Confident	196 Å²	196	121.8 Å²	121.8	97%	0.966	63%	0.629	S	S	*	*				0	76.7	0	-76.2	-83.9	166.3	0	0	109.1	G3	M1-G3 PolarHBondContact O-N 3.47Å
2	P	62.2	Low	81.5	Confident	104 Å²	104	122.4 Å²	122.4	68%	0.675	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.2	-15.9	-172.3	24.7	-32.3	0	0	0	114.8	R4	P2-R4 PolarHBondContact O-N 3.45Å
3	G	76.2	Confident	82	Confident	53 Å²	53	122 Å²	122	55%	0.546	63%	0.631	S	S	.	*	H	α-helix	trans	-68	-29.9	179.6	0	0	0	0	0	114.7	M1 T5 E7	M1-G3 PolarHBondContact O-N 3.47Å; G3-T5 PolarHBondContact O-N 3.24Å; G3-E7 PolarHBondContact O-N 3.47Å
4	R	78.3	Confident	82.3	Confident	190 Å²	190	121.7 Å²	121.7	72%	0.717	63%	0.63	S	S	*	*	H	α-helix	trans	-71.8	-28.6	-178.5	-71.4	-150.2	-98.6	153.6	-9.7	113.2	P2 L8	P2-R4 PolarHBondContact O-N 3.45Å; R4-L8 PolarHBondContact O-N 3.38Å; R4-L8 WeakPolarHBondContact O-CG 3.33Å
5	T	83.1	Confident	82.4	Confident	88 Å²	88	116.7 Å²	116.7	54%	0.54	62%	0.62	S	S	.	*	H	α-helix	trans	-73.9	-37.8	-179.3	-28.3	0	0	0	0	111.7	G3 L8 C9	G3-T5 PolarHBondContact O-N 3.24Å; T5-L8 PolarHBondContact O-N 3.47Å; T5-C9 PolarHBondContact O-N 2.99Å; T5-C9 PolarHBondContact O-SG 3.34Å; T5-C9 VanDerWaalsContact O-SG 3.39Å
6	W	86.1	Confident	82.3	Confident	185 Å²	185	117.6 Å²	117.6	70%	0.701	62%	0.624	S	S	*	*	H	α-helix	trans	-65.9	-40.2	177	-82.9	91.9	0	0	0	112.5	L8 C9 L10	W6-L8 VanDerWaalsContact C-N 3.32Å; W6-L8 PolarHBondContact O-N 2.93Å; W6-C9 PolarHBondContact O-N 3.24Å; W6-L10 WeakPolarHBondContact O-CG 3.29Å; W6-L10 PolarHBondContact O-N 3.05Å
7	E	88.8	Confident	81.7	Confident	129 Å²	129	113.1 Å²	113.1	60%	0.603	61%	0.612	S	S	*	*	H	α-helix	trans	-61.1	-41.8	176.1	-162.9	-179.8	96.9	0	0	111.6	G3 L10 L11	G3-E7 PolarHBondContact O-N 3.47Å; E7-L10 PolarHBondContact O-N 3.39Å; E7-L11 HydrophobicContact CG-CD1 4.5Å; E7-L11 VanDerWaalsContact O-CG 3.29Å; E7-L11 WeakPolarHBondContact O-CG 3.4Å; E7-L11 PolarHBondContact O-N 3.41Å
8	L	89.1	Confident	80.9	Confident	113 Å²	113	113.5 Å²	113.5	59%	0.592	61%	0.614	S	S	*	*	H	α-helix	trans	-64.9	-40.5	174.9	-66.8	170.4	0	0	0	112.5	R4 T5 W6 L11 L12	R4-L8 PolarHBondContact O-N 3.38Å; R4-L8 WeakPolarHBondContact O-CG 3.33Å; T5-L8 PolarHBondContact O-N 3.47Å; W6-L8 VanDerWaalsContact C-N 3.32Å; W6-L8 PolarHBondContact O-N 2.93Å; L8-L11 PolarHBondContact O-N 3.5Å; L8-L12 PolarHBondContact O-N 3.45Å; L8-L12 WeakPolarHBondContact O-CB 3.35Å
9	C	87.9	Confident	80	Confident	66 Å²	66	110.3 Å²	110.3	45%	0.446	61%	0.609	S	S	.	*	H	α-helix	trans	-63.4	-42.3	174.8	-71.5	0	0	0	0	111.9	T5 W6 L12 L13	T5-C9 PolarHBondContact O-N 2.99Å; T5-C9 PolarHBondContact O-SG 3.34Å; T5-C9 VanDerWaalsContact O-SG 3.39Å; W6-C9 PolarHBondContact O-N 3.24Å; C9-L12 PolarHBondContact O-N 3.39Å; C9-L13 VanDerWaalsContact O-CD1 3.25Å; C9-L13 WeakPolarHBondContact O-CD1 3.41Å; C9-L13 PolarHBondContact O-N 3Å
10	L	89.9	Confident	79.2	Confident	112 Å²	112	107.9 Å²	107.9	59%	0.586	60%	0.601	S	S	*	*	H	α-helix	trans	-64	-42.9	177.4	-71.6	169.5	0	0	0	111.9	W6 E7 L12 L13 L14	W6-L10 WeakPolarHBondContact O-CG 3.29Å; W6-L10 PolarHBondContact O-N 3.05Å; E7-L10 PolarHBondContact O-N 3.39Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3Å; L10-L13 PolarHBondContact O-N 2.98Å; L10-L14 WeakPolarHBondContact O-CB 3.37Å; L10-L14 PolarHBondContact O-N 2.97Å
11	L	90.7	Very high	78.3	Confident	104 Å²	104	109.5 Å²	109.5	55%	0.545	60%	0.604	S	S	.	*	H	α-helix	trans	-62.1	-39.7	175.3	-72.4	167.3	0	0	0	112	E7 L8 L14 G15	E7-L11 HydrophobicContact CG-CD1 4.5Å; E7-L11 VanDerWaalsContact O-CG 3.29Å; E7-L11 WeakPolarHBondContact O-CG 3.4Å; E7-L11 PolarHBondContact O-N 3.41Å; L8-L11 PolarHBondContact O-N 3.5Å; L11-L14 PolarHBondContact O-N 3.47Å; L11-G15 PolarHBondContact O-N 3.08Å; L11-G15 VanDerWaalsContact O-N 3.08Å
12	L	88.2	Confident	78.3	Confident	129 Å²	129	109.2 Å²	109.2	68%	0.675	60%	0.6	S	S	*	*	H	α-helix	trans	-67	-43.9	177.6	-168.2	71.3	0	0	0	112.1	L8 C9 L10 L14 G15 L16	L8-L12 PolarHBondContact O-N 3.45Å; L8-L12 WeakPolarHBondContact O-CB 3.35Å; C9-L12 PolarHBondContact O-N 3.39Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3Å; L12-L14 VanDerWaalsContact C-N 3.33Å; L12-L14 PolarHBondContact O-N 3.32Å; L12-G15 PolarHBondContact O-N 2.98Å; L12-L16 WeakPolarHBondContact O-CB 3.34Å; L12-L16 PolarHBondContact O-N 3.48Å
13	L	87.3	Confident	78.2	Confident	117 Å²	117	108 Å²	108	61%	0.613	60%	0.599	S	S	*	*	H	α-helix	trans	-62.8	-40.6	176.2	-96.9	69.2	0	0	0	111.7	C9 L10 L16 G17	C9-L13 VanDerWaalsContact O-CD1 3.25Å; C9-L13 WeakPolarHBondContact O-CD1 3.41Å; C9-L13 PolarHBondContact O-N 3Å; L10-L13 PolarHBondContact O-N 2.98Å; L13-L16 PolarHBondContact O-N 3.3Å; L13-G17 PolarHBondContact O-N 3.41Å
14	L	86.2	Confident	77.5	Confident	118 Å²	118	111.1 Å²	111.1	62%	0.618	60%	0.603	S	S	*	*	H	α-helix	trans	-63.4	-44.2	177.9	-173.9	63.4	0	0	0	111.5	L10 L11 L12 L16 L18	L10-L14 WeakPolarHBondContact O-CB 3.37Å; L10-L14 PolarHBondContact O-N 2.97Å; L11-L14 PolarHBondContact O-N 3.47Å; L12-L14 VanDerWaalsContact C-N 3.33Å; L12-L14 PolarHBondContact O-N 3.32Å; L14-L16 VanDerWaalsContact C-N 3.34Å; L14-L18 WeakPolarHBondContact O-CD1 3.25Å; L14-L18 WeakPolarHBondContact O-CG 3.41Å; L14-L18 PolarHBondContact O-N 3.39Å
15	G	83.9	Confident	76.7	Confident	47 Å²	47	106.9 Å²	106.9	49%	0.485	60%	0.6	S	S	.	*	H	α-helix	trans	-64.8	-35.5	174.7	0	0	0	0	0	113.4	L11 L12 G19	L11-G15 PolarHBondContact O-N 3.08Å; L11-G15 VanDerWaalsContact O-N 3.08Å; L12-G15 PolarHBondContact O-N 2.98Å; G15-G19 PolarHBondContact O-N 3.48Å
16	L	80.6	Confident	75.7	Confident	130 Å²	130	107.1 Å²	107.1	68%	0.681	60%	0.603	S	S	*	*	H	α-helix	trans	-71.7	-40.2	179.6	-170.3	66.1	0	0	0	112.6	L12 L13 L14 L18 G19 S20	L12-L16 WeakPolarHBondContact O-CB 3.34Å; L12-L16 PolarHBondContact O-N 3.48Å; L13-L16 PolarHBondContact O-N 3.3Å; L14-L16 VanDerWaalsContact C-N 3.34Å; L16-L18 VanDerWaalsContact C-N 3.28Å; L16-L18 PolarHBondContact O-N 3.35Å; L16-G19 PolarHBondContact O-N 3.4Å; L16-S20 WeakPolarHBondContact O-CB 3.39Å; L16-S20 PolarHBondContact O-N 3Å
17	G	72.5	Confident	74.7	Confident	41 Å²	41	104.4 Å²	104.4	42%	0.423	61%	0.609	S	S	.	*	H	α-helix	trans	-65.6	-30.2	177.7	0	0	0	0	0	113.6	L13	L13-G17 PolarHBondContact O-N 3.41Å
18	L	66.7	Low	73.4	Confident	121 Å²	121	103.2 Å²	103.2	63%	0.634	61%	0.614	S	S	*	*	H	α-helix	trans	-70.9	-38.1	176.5	-73.3	161.1	0	0	0	112.3	L14 L16	L14-L18 WeakPolarHBondContact O-CD1 3.25Å; L14-L18 WeakPolarHBondContact O-CG 3.41Å; L14-L18 PolarHBondContact O-N 3.39Å; L16-L18 VanDerWaalsContact C-N 3.28Å; L16-L18 PolarHBondContact O-N 3.35Å
19	G	64.6	Low	71.8	Confident	52 Å²	52	106.4 Å²	106.4	54%	0.536	63%	0.626	S	S	.	*	H	α-helix	trans	-80.3	-20.8	174.6	0	0	0	0	0	114.4	G15 L16 Q21 E22	G15-G19 PolarHBondContact O-N 3.48Å; L16-G19 PolarHBondContact O-N 3.4Å; G19-Q21 VanDerWaalsContact C-N 3.31Å; G19-Q21 PolarHBondContact O-N 3.45Å; G19-E22 PolarHBondContact O-N 3.49Å
20	S	64.7	Low	70.6	Confident	62 Å²	62	114 Å²	114	43%	0.434	65%	0.645	S	S	.	*	G	3₁₀ helix	trans	-78.5	-11.5	-178.2	-169.4	0	0	0	0	114	L16 E22 A23 L24	L16-S20 WeakPolarHBondContact O-CB 3.39Å; L16-S20 PolarHBondContact O-N 3Å; S20-E22 VanDerWaalsContact C-N 3.31Å; S20-A23 PolarHBondContact O-N 3.5Å; S20-L24 PolarHBondContact O-N 3.49Å
21	Q	59.6	Low	69.2	Low	143 Å²	143	114.9 Å²	114.9	67%	0.668	66%	0.655	S	S	*	*	G	3₁₀ helix	trans	-76.3	-18	174.1	-73.7	-178.1	103	0	0	113.1	G19 A23	G19-Q21 VanDerWaalsContact C-N 3.31Å; G19-Q21 PolarHBondContact O-N 3.45Å; Q21-A23 PolarHBondContact O-N 3.34Å; Q21-A23 VanDerWaalsContact C-N 3.26Å
22	E	57.5	Low	67.3	Low	189 Å²	189	113.6 Å²	113.6	88%	0.883	66%	0.655	S	S	*	*	G	3₁₀ helix	trans	-80	-9.4	175	-155.1	89.5	75.2	0	0	112.2	G19 S20	G19-E22 PolarHBondContact O-N 3.49Å; S20-E22 VanDerWaalsContact C-N 3.31Å
23	A	60.6	Low	66	Low	79 Å²	79	113 Å²	113	65%	0.653	66%	0.659	S	S	*	*	S	Bend	trans	-124.2	0.3	-176.8	0	0	0	0	0	114.1	S20 Q21 P25	S20-A23 PolarHBondContact O-N 3.5Å; Q21-A23 PolarHBondContact O-N 3.34Å; Q21-A23 VanDerWaalsContact C-N 3.26Å; A23-P25 VanDerWaalsContact O-CD 3.31Å; A23-P25 WeakPolarHBondContact O-CD 3.31Å
24	L	61.3	Low	64.8	Low	119 Å²	119	111.4 Å²	111.4	62%	0.623	66%	0.662	S	S	*	*	S	Bend	trans	-71.6	115.3	163.5	-82.2	162.9	0	0	0	105.9	S20	S20-L24 PolarHBondContact O-N 3.49Å
25	P	61.7	Low	63.3	Low	101 Å²	101	113.1 Å²	113.1	66%	0.656	67%	0.672	S	S	*	*			trans	-51.7	139.6	173.7	23.4	-32.3	0	0	0	107.1	A23	A23-P25 VanDerWaalsContact O-CD 3.31Å; A23-P25 WeakPolarHBondContact O-CD 3.31Å
26	P	61.8	Low	62.3	Low	93 Å²	93	118.7 Å²	118.7	60%	0.604	69%	0.69	S	S	*	*			trans	-45.6	135.2	176	19.8	-31.7	0	0	0	107.5	C28	P26-C28 WeakPolarHBondContact O-CA 3.46Å; P26-C28 PolarHBondContact O-N 2.71Å
27	P	65.8	Low	61	Low	127 Å²	127	124.2 Å²	124.2	83%	0.825	71%	0.712	S	S	*	*	S	Bend	trans	-50.7	115	-177.1	23.1	-32.2	0	0	0	105.2	E29	P27-E29 PolarHBondContact O-N 3.07Å
28	C	60	Low	60.4	Low	105 Å²	105	128.4 Å²	128.4	71%	0.709	73%	0.726	S	S	*	*			trans	-30.3	118.7	-164.1	-59.7	0	0	0	0	108.7	P26 R30	P26-C28 WeakPolarHBondContact O-CA 3.46Å; P26-C28 PolarHBondContact O-N 2.71Å; C28-R30 WeakPolarHBondContact O-CG 3.45Å; C28-R30 PolarHBondContact O-N 2.83Å
29	E	55.6	Low	60.1	Low	180 Å²	180	128.8 Å²	128.8	84%	0.841	73%	0.731	S	S	*	*			trans	-54.4	88.4	163.8	-76.4	179.2	87.4	0	0	104.8	P27 T31	P27-E29 PolarHBondContact O-N 3.07Å; E29-T31 PolarHBondContact O-N 2.58Å
30	R	63.8	Low	59.8	Low	225 Å²	225	133.1 Å²	133.1	85%	0.849	74%	0.742	S	S	*	*			trans	-63.7	101.7	171.6	-66.9	-174.7	-172.8	-177.6	2.3	100	C28 S32	C28-R30 WeakPolarHBondContact O-CG 3.45Å; C28-R30 PolarHBondContact O-N 2.83Å; R30-S32 VanDerWaalsContact C-N 3.28Å; R30-S32 PolarHBondContact O-N 2.82Å
31	T	59.8	Low	59.5	Low	131 Å²	131	137.2 Å²	137.2	80%	0.804	76%	0.76	S	S	*	*			trans	-23.5	97.3	173.6	-59.9	0	0	0	0	107.8	E29 P33	E29-T31 PolarHBondContact O-N 2.58Å; T31-P33 VanDerWaalsContact O-CD 3.29Å; T31-P33 WeakPolarHBondContact O-CD 3.29Å; T31-P33 VanDerWaalsContact O-N 3.16Å
32	S	51.8	Low	59.5	Low	77 Å²	77	136.9 Å²	136.9	54%	0.538	77%	0.766	S	S	.	*			trans	-64.7	122.2	175.7	-178.2	0	0	0	0	102.8	R30 A34 D35	R30-S32 VanDerWaalsContact C-N 3.28Å; R30-S32 PolarHBondContact O-N 2.82Å; S32-A34 PolarHBondContact O-N 3.25Å; S32-D35 PolarHBondContact O-N 2.76Å
33	P	60.3	Low	59.6	Low	117 Å²	117	133.4 Å²	133.4	76%	0.76	76%	0.758	S	S	*	*	T	Hydrogen-bonded Turn	trans	-63.7	9.6	180	26.5	-33.9	0	0	0	113.1	T31	T31-P33 VanDerWaalsContact O-CD 3.29Å; T31-P33 WeakPolarHBondContact O-CD 3.29Å; T31-P33 VanDerWaalsContact O-N 3.16Å
34	A	61.5	Low	59.6	Low	82 Å²	82	137.3 Å²	137.3	68%	0.678	77%	0.765	S	S	*	*	T	Hydrogen-bonded Turn	trans	-89.4	-10	175.7	0	0	0	0	0	114.7	S32	S32-A34 PolarHBondContact O-N 3.25Å
35	D	56.2	Low	59.4	Low	155 Å²	155	138.7 Å²	138.7	83%	0.829	78%	0.776	S	S	*	*	S	Bend	trans	-95.1	0.6	174.5	-158.4	-113.5	0	0	0	112.8	S32 H37	S32-D35 PolarHBondContact O-N 2.76Å; D35-H37 PolarHBondContact O-N 3.48Å
36	L	63.2	Low	59.3	Low	164 Å²	164	141.8 Å²	141.8	86%	0.859	79%	0.786	S	S	*	*			trans	-97.8	63.2	169.4	-158.2	83.1	0	0	0	109.6
37	H	51.4	Low	59	Low	246 Å²	246	146.3 Å²	146.3	100%	1.139	80%	0.803	S	S	*	*			trans	-151.2	0	164.8	-160.1	-101.7	0	0	0	112.2	D35	D35-H37 PolarHBondContact O-N 3.48Å

Retrieved 37 of 37 residues in 20.2 ms (Link to these results)

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