A0A087WTJ9_HUMAN Loading...

E3 ubiquitin-protein ligase

Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

AlphaFold DB , UniProt , Accession A0A087WTJ9, Species HUMAN (Homo sapiens, Human), Gene UBR1, Length 1,070 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M30.7Very low28.5Very low240 Ų240147.5 Ų147.5100%1.18284%0.836SS**  0122.90-92.1-178.763.100105.3
2A30.3Very low28.2Very low82 Ų82148.3 Ų148.368%0.67883%0.83SS**  trans66.6126-162.100000111.5
3D29.6Very low28.3Very low141 Ų141151.2 Ų151.275%0.75483%0.833SS**  cis64.214333.6-41-46.4000110.4
4E30.7Very low28.6Very low180 Ų180148 Ų14884%0.84181%0.813SS**  cis-148.4167.8-10.2-105.6155.4145.400104.8
5E28.7Very low29.1Very low174 Ų174146.4 Ų146.481%0.81382%0.816SS**  cis-150173.316-156.7-167.6133.900108.8
6A30.1Very low29.8Very low97 Ų97141.1 Ų141.180%0.80280%0.797SS**  trans-142.7106.9163.100000110.3G8A6-G8 PolarHBondContact O-N 3.11Å
7G26.2Very low30.8Very low71 Ų71144.1 Ų144.173%0.73280%0.803SS**  trans-67.4118.2179.700000111.6
8G24.3Very low32.1Very low75 Ų75138.9 Ų138.977%0.77377%0.773SS**  trans-75.6124.5177.300000112.1A6A6-G8 PolarHBondContact O-N 3.11Å
9T27.6Very low33.6Very low138 Ų138133.7 Ų133.785%0.84775%0.747SS**  trans-76.9114.8156.927.40000108.8R11T9-R11 PolarHBondContact O-N 3.23Å
10E27.1Very low35.1Very low186 Ų186136.6 Ų136.687%0.86975%0.754SS**  trans-59.9120.6174.6-67.7178.513000110.3M12E10-M12 PolarHBondContact O-N 3.3Å
11R27.8Very low37Very low239 Ų239133 Ų13390%0.90274%0.735SS**  trans-69.2110.4159.4-81.3-177.5169.6-172.8-5.3107.4T9 E13T9-R11 PolarHBondContact O-N 3.23Å; R11-E13 PolarHBondContact O-N 3.43Å
12M25.5Very low39.2Very low156 Ų156122.9 Ų122.977%0.76869%0.688SS**  trans-66.598.8165.1-79.9-17868.800109.3E10 I14E10-M12 PolarHBondContact O-N 3.3Å; M12-I14 VanDerWaalsContact C-N 3.3Å; M12-I14 HydrophobicContact CB-CG1 4.35Å; M12-I14 HydrophobicContact CE-CD1 3.99Å; M12-I14 HydrophobicContact CE-CG1 4.14Å; M12-I14 PolarHBondContact O-N 3.3Å
13E29.1Very low41.5Very low186 Ų186124 Ų12487%0.86968%0.679SS**  trans-69.287.1163.9-72.9-172.915200109.6R11 S15R11-E13 PolarHBondContact O-N 3.43Å; E13-S15 PolarHBondContact O-N 2.83Å
14I32.4Very low43.8Very low107 Ų107125.4 Ų125.455%0.54967%0.674SS.*  trans-80.975.8165.7-52.2-177.4000108.3M12 A16M12-I14 VanDerWaalsContact C-N 3.3Å; M12-I14 HydrophobicContact CB-CG1 4.35Å; M12-I14 HydrophobicContact CE-CD1 3.99Å; M12-I14 HydrophobicContact CE-CG1 4.14Å; M12-I14 PolarHBondContact O-N 3.3Å; I14-A16 HydrophobicContact CG2-CB 4.15Å; I14-A16 PolarHBondContact O-N 2.86Å; I14-A16 VanDerWaalsContact O-N 3.12Å
15S35.7Very low46.2Very low124 Ų124117.1 Ų117.187%0.86764%0.635SS**  trans-75.690.8164.4-176.40000109E13E13-S15 PolarHBondContact O-N 2.83Å
16A40.5Very low48.7Very low62 Ų62109.2 Ų109.251%0.51260%0.6SS.*  trans-130.4120.2172.500000109.2I14 L18I14-A16 HydrophobicContact CG2-CB 4.15Å; I14-A16 PolarHBondContact O-N 2.86Å; I14-A16 VanDerWaalsContact O-N 3.12Å; A16-L18 PolarHBondContact O-N 2.98Å
17E47.3Very low51Low192 Ų192107.7 Ų107.790%0.89758%0.583SS**PPolyproline II helixtrans-58.7129.3174.1-66.3-178.8144.200110.1
18L55.1Low53.7Low50 Ų50106.9 Ų106.926%0.26256%0.558SS.*PPolyproline II helixtrans-59.7132.8-179.3-82.7170.2000111.2A16 Q20 L25 H42 Q45A16-L18 PolarHBondContact O-N 2.98Å; L18-Q20 PolarHBondContact O-N 2.89Å; L18-L25 HydrophobicContact CD2-CD1 4.12Å; L18-H42 WeakPolarHBondContact CD2-ND1 3.33Å; L18-Q45 VanDerWaalsContact CD1-OE1 3.26Å
19P59.8Low56.5Low41 Ų41103.3 Ų103.327%0.26652%0.521SS..PPolyproline II helixtrans-60.6126-178.5-24.532.4000114T21 R24 L25 W28P19-T21 VanDerWaalsContact C-N 3.27Å; P19-T21 PolarHBondContact O-N 3.1Å; P19-T21 VanDerWaalsContact O-N 3.12Å; P19-R24 HydrophobicContact CB-CB 3.67Å; P19-L25 HydrophobicContact CG-CD1 4.47Å; P19-W28 HydrophobicContact CG-CB 4.18Å; P19-W28 HydrophobicContact CG-CG 4.46Å
20Q63.1Low59Low191 Ų191100.6 Ų100.689%0.89350%0.502SS*.SBendtrans-72.71-173.2-66-174.8-9.800116.8L18L18-Q20 PolarHBondContact O-N 2.89Å
21T76.1Confident61.5Low60 Ų6098.7 Ų98.737%0.36849%0.493SS..SBendtrans-133142.9177.466.10000112.2P19 Q23 R24 L25P19-T21 VanDerWaalsContact C-N 3.27Å; P19-T21 PolarHBondContact O-N 3.1Å; P19-T21 VanDerWaalsContact O-N 3.12Å; T21-Q23 VanDerWaalsContact C-N 3.33Å; T21-Q23 PolarHBondContact O-N 3.34Å; T21-R24 PolarHBondContact O-N 3.36Å; T21-R24 WeakPolarHBondContact OG1-CD 3.46Å; T21-R24 WeakPolarHBondContact OG1-CG 3.29Å; T21-L25 PolarHBondContact O-N 2.95Å; T21-L25 VanDerWaalsContact O-N 3.12Å
22P77.1Confident64.1Low29 Ų2990.2 Ų90.219%0.18846%0.464CS..Hα-helixtrans-53.4-43.1-174.7-31.336.9000115R24 L25 A26 T72 P73P22-R24 VanDerWaalsContact C-N 3.33Å; P22-R24 PolarHBondContact O-N 2.85Å; P22-L25 PolarHBondContact O-N 3.31Å; P22-A26 PolarHBondContact O-N 2.76Å; P22-T72 HydrophobicContact CB-CG2 3.99Å; P22-T72 HydrophobicContact CG-CG2 4.18Å; P22-P73 HydrophobicContact CB-CB 4.47Å; P22-P73 HydrophobicContact CB-CG 3.9Å; P22-P73 HydrophobicContact CG-CG 4.38Å
23Q77.9Confident66.6Low104 Ų10490.3 Ų90.349%0.48647%0.473SS..Hα-helixtrans-59.1-39.5175.8-73.7176.2-27.800113.4T21 S27 W76T21-Q23 VanDerWaalsContact C-N 3.33Å; T21-Q23 PolarHBondContact O-N 3.34Å; Q23-S27 WeakPolarHBondContact O-CB 3.43Å; Q23-S27 PolarHBondContact O-N 3.25Å; Q23-S27 PolarHBondContact O-OG 3.39Å; Q23-W76 HydrophobicContact CG-CD2 3.67Å; Q23-W76 HydrophobicContact CG-CE3 3.72Å; Q23-W76 HydrophobicContact CG-CG 4.38Å; Q23-W76 HydrophobicContact CG-CH2 3.96Å; Q23-W76 HydrophobicContact CG-CZ2 3.89Å; Q23-W76 HydrophobicContact CG-CZ3 3.85Å
24R78.6Confident69.2Low171 Ų17185 Ų8565%0.64545%0.45SS*.Hα-helixtrans-74-34.3-179.6-71.5-180175.5-175.2-0.2111.5P19 T21 P22 S27 W28P19-R24 HydrophobicContact CB-CB 3.67Å; T21-R24 PolarHBondContact O-N 3.36Å; T21-R24 WeakPolarHBondContact OG1-CD 3.46Å; T21-R24 WeakPolarHBondContact OG1-CG 3.29Å; P22-R24 VanDerWaalsContact C-N 3.33Å; P22-R24 PolarHBondContact O-N 2.85Å; R24-S27 PolarHBondContact O-N 3.33Å; R24-W28 WeakPolarHBondContact O-CB 3.43Å; R24-W28 PolarHBondContact O-N 3.06Å
25L80.6Confident71.9Confident6 Ų680.5 Ų80.53%0.03143%0.427CS..Hα-helixtrans-68.5-43.8174.4-174.567.2000111.4L18 P19 T21 P22 S27 W28 W29 H42 P73L18-L25 HydrophobicContact CD2-CD1 4.12Å; P19-L25 HydrophobicContact CG-CD1 4.47Å; T21-L25 PolarHBondContact O-N 2.95Å; T21-L25 VanDerWaalsContact O-N 3.12Å; P22-L25 PolarHBondContact O-N 3.31Å; L25-S27 VanDerWaalsContact C-N 3.3Å; L25-S27 PolarHBondContact O-N 2.98Å; L25-W28 HydrophobicContact CD1-CE3 4.02Å; L25-W28 WeakPolarHBondContact O-CB 3.42Å; L25-W28 PolarHBondContact O-N 2.96Å; L25-W29 HydrophobicContact CD2-CH2 4Å; L25-W29 HydrophobicContact CD2-CZ2 4.14Å; L25-W29 HydrophobicContact CD2-CZ3 4.45Å; L25-W29 HydrophobicContact CG-CD2 4.48Å; L25-W29 HydrophobicContact CG-CH2 4.33Å; L25-W29 HydrophobicContact CG-CZ2 4.28Å; L25-W29 HydrophobicContact CG-CZ3 4.46Å; L25-W29 PolarHBondContact O-N 3.39Å; L25-H42 WeakPolarHBondContact CD2-CE1 3.44Å; L25-H42 WeakPolarHBondContact CD2-NE2 3.45Å; L25-P73 HydrophobicContact CB-CB 4.42Å; L25-P73 HydrophobicContact CD2-CB 3.76Å; L25-P73 HydrophobicContact CD2-CG 3.89Å; L25-P73 HydrophobicContact CG-CB 4.35Å
26A79.9Confident74.5Confident8 Ų876.5 Ų76.57%0.06639%0.393CS..Hα-helixtrans-57-43.8171.500000112.1P22 W28 W29 D30 W76P22-A26 PolarHBondContact O-N 2.76Å; A26-W28 VanDerWaalsContact C-N 3.28Å; A26-W28 PolarHBondContact O-N 3.17Å; A26-W29 PolarHBondContact O-N 3.44Å; A26-D30 PolarHBondContact O-N 3.09Å; A26-D30 VanDerWaalsContact O-N 3.17Å; A26-W76 HydrophobicContact CB-CB 3.8Å
27S79.3Confident76.7Confident65 Ų6577.8 Ų77.846%0.45539%0.394SS..Hα-helixtrans-65.1-29.3175.4-56.40000113.3Q23 R24 L25 Q31Q23-S27 WeakPolarHBondContact O-CB 3.43Å; Q23-S27 PolarHBondContact O-N 3.25Å; Q23-S27 PolarHBondContact O-OG 3.39Å; R24-S27 PolarHBondContact O-N 3.33Å; L25-S27 VanDerWaalsContact C-N 3.3Å; L25-S27 PolarHBondContact O-N 2.98Å; S27-Q31 WeakPolarHBondContact O-CG 3.48Å; S27-Q31 PolarHBondContact O-NE2 3.03Å; S27-Q31 VanDerWaalsContact O-NE2 3.11Å
28W83.4Confident78.7Confident54 Ų5469 Ų6921%0.20536%0.355CS..Hα-helixtrans-74.6-39.7176175.980.9000111.6P19 R24 L25 A26 Q31 Q32 A38P19-W28 HydrophobicContact CG-CB 4.18Å; P19-W28 HydrophobicContact CG-CG 4.46Å; R24-W28 WeakPolarHBondContact O-CB 3.43Å; R24-W28 PolarHBondContact O-N 3.06Å; L25-W28 HydrophobicContact CD1-CE3 4.02Å; L25-W28 WeakPolarHBondContact O-CB 3.42Å; L25-W28 PolarHBondContact O-N 2.96Å; A26-W28 VanDerWaalsContact C-N 3.28Å; A26-W28 PolarHBondContact O-N 3.17Å; W28-Q31 PolarHBondContact O-N 3.21Å; W28-Q32 HydrophobicContact CD2-CG 4.5Å; W28-Q32 HydrophobicContact CH2-CG 4.45Å; W28-Q32 HydrophobicContact CZ2-CG 4.36Å; W28-Q32 WeakPolarHBondContact O-CG 3.4Å; W28-Q32 PolarHBondContact O-NE2 3.48Å; W28-A38 HydrophobicContact CH2-CB 3.95Å; W28-A38 HydrophobicContact CZ3-CB 4.08Å
29W83Confident80.4Confident0 Ų066.6 Ų66.60%034%0.342CS..Hα-helixtrans-63.7-40.4174.9-79.2-34.3000113.2L25 A26 Q31 Q32 F35 F39 H42 P73 L74 Y77L25-W29 HydrophobicContact CD2-CH2 4Å; L25-W29 HydrophobicContact CD2-CZ2 4.14Å; L25-W29 HydrophobicContact CD2-CZ3 4.45Å; L25-W29 HydrophobicContact CG-CD2 4.48Å; L25-W29 HydrophobicContact CG-CH2 4.33Å; L25-W29 HydrophobicContact CG-CZ2 4.28Å; L25-W29 HydrophobicContact CG-CZ3 4.46Å; L25-W29 PolarHBondContact O-N 3.39Å; A26-W29 PolarHBondContact O-N 3.44Å; W29-Q31 PolarHBondContact O-N 3.25Å; W29-Q32 PolarHBondContact O-N 3.34Å; W29-Q32 VanDerWaalsContact O-N 3.09Å; W29-F35 HydrophobicContact CB-CD2 3.98Å; W29-F35 HydrophobicContact CB-CE2 3.96Å; W29-F35 AromaticContact CD2-CE2 3.86Å; W29-F35 HydrophobicContact CD2-CE2 3.86Å; W29-F35 HydrophobicContact CE3-CE2 4.23Å; W29-F35 HydrophobicContact CG-CD2 4.06Å; W29-F35 AromaticContact CG-CE2 3.73Å; W29-F35 HydrophobicContact CG-CE2 3.73Å; W29-F39 HydrophobicContact CZ2-CD2 4.21Å; W29-H42 HydrophobicContact CZ2-CB 4.21Å; W29-H42 AromaticContact CZ2-CD2 3.59Å; W29-H42 AromaticContact CZ2-CG 3.9Å; W29-P73 HydrophobicContact CH2-CB 3.98Å; W29-P73 HydrophobicContact CZ3-CB 3.65Å; W29-L74 HydrophobicContact CH2-CD2 4.09Å; W29-L74 HydrophobicContact CH2-CG 4.15Å; W29-L74 HydrophobicContact CZ3-CD2 3.87Å; W29-L74 HydrophobicContact CZ3-CG 4.05Å; W29-Y77 HydrophobicContact CB-CD1 4.27Å; W29-Y77 HydrophobicContact CB-CE1 4.26Å; W29-Y77 HydrophobicContact CB-CG 4.43Å; W29-Y77 HydrophobicContact CE3-CD1 4.34Å; W29-Y77 HydrophobicContact CE3-CG 4.49Å
30D79.2Confident81.9Confident82 Ų8265 Ų6544%0.43933%0.331SS..THydrogen-bonded Turntrans-64.1-21.6176.6-162.753.7000113.1A26 Y77 Q189 K192A26-D30 PolarHBondContact O-N 3.09Å; A26-D30 VanDerWaalsContact O-N 3.17Å; D30-Y77 HydrophobicContact CB-CD2 4.18Å; D30-Y77 HydrophobicContact CB-CE2 3.59Å; D30-Q189 PolarHBondContact OD1-NE2 3.12Å; D30-K192 IonicContact OD1-NZ 3.36Å; D30-K192 PolarHBondContact OD1-NZ 3.42Å
31Q80.8Confident83.1Confident146 Ų14659.2 Ų59.268%0.68230%0.304SS*.THydrogen-bonded Turntrans-86.1-9.3176.6-67.5169.131.200113.7S27 W28 W29S27-Q31 WeakPolarHBondContact O-CG 3.48Å; S27-Q31 PolarHBondContact O-NE2 3.03Å; S27-Q31 VanDerWaalsContact O-NE2 3.11Å; W28-Q31 PolarHBondContact O-N 3.21Å; W29-Q31 PolarHBondContact O-N 3.25Å
32Q82.1Confident83.7Confident61 Ų6156.6 Ų56.629%0.28529%0.288SS..  trans-82.8140.6-179.3-57.2-47.8-53.200111.8W28 W29 A38W28-Q32 HydrophobicContact CD2-CG 4.5Å; W28-Q32 HydrophobicContact CH2-CG 4.45Å; W28-Q32 HydrophobicContact CZ2-CG 4.36Å; W28-Q32 WeakPolarHBondContact O-CG 3.4Å; W28-Q32 PolarHBondContact O-NE2 3.48Å; W29-Q32 PolarHBondContact O-N 3.34Å; W29-Q32 VanDerWaalsContact O-N 3.09Å; Q32-A38 HydrophobicContact CB-CB 3.99Å; Q32-A38 HydrophobicContact CG-CB 3.65Å
33V76.8Confident84.5Confident158 Ų15855.2 Ų55.296%0.95828%0.279SS*.SBendtrans-70.2-38178-178.80000111.4
34D85.8Confident85Confident74 Ų7450.4 Ų50.440%0.39626%0.256SS..  trans-120.5109.4170.1179.419.4000110.3Y36 T37 A38D34-Y36 VanDerWaalsContact C-N 3.29Å; D34-Y36 PolarHBondContact O-N 3.12Å; D34-Y36 WeakPolarHBondContact OD1-CB 3.37Å; D34-Y36 PolarHBondContact OD1-N 3Å; D34-T37 WeakPolarHBondContact OD2-CB 3.11Å; D34-T37 PolarHBondContact OD2-N 3.23Å; D34-T37 PolarHBondContact OD2-OG1 3.04Å; D34-A38 PolarHBondContact O-N 2.96Å
35F88.7Confident85.5Confident13 Ų1344.7 Ų44.76%0.05724%0.237CC..Hα-helixtrans-64.1-33.3174.8174.5-104.8000112.1W29 A38 F39 L74 Y77 I193W29-F35 HydrophobicContact CB-CD2 3.98Å; W29-F35 HydrophobicContact CB-CE2 3.96Å; W29-F35 AromaticContact CD2-CE2 3.86Å; W29-F35 HydrophobicContact CD2-CE2 3.86Å; W29-F35 HydrophobicContact CE3-CE2 4.23Å; W29-F35 HydrophobicContact CG-CD2 4.06Å; W29-F35 AromaticContact CG-CE2 3.73Å; W29-F35 HydrophobicContact CG-CE2 3.73Å; F35-A38 PolarHBondContact O-N 2.68Å; F35-F39 HydrophobicContact CE1-CB 4.23Å; F35-F39 HydrophobicContact CE1-CG 4.36Å; F35-F39 HydrophobicContact CE2-CB 4.4Å; F35-F39 HydrophobicContact CZ-CB 4.12Å; F35-F39 HydrophobicContact CZ-CD2 4.17Å; F35-F39 HydrophobicContact CZ-CG 4.2Å; F35-F39 WeakPolarHBondContact O-CB 3.2Å; F35-F39 PolarHBondContact O-N 3.06Å; F35-L74 HydrophobicContact CZ-CD2 4.02Å; F35-Y77 HydrophobicContact CD2-CD1 4.18Å; F35-Y77 AromaticContact CD2-CE1 3.42Å; F35-Y77 HydrophobicContact CD2-CE1 3.42Å; F35-Y77 VanDerWaalsContact CD2-CE1 3.42Å; F35-Y77 AromaticContact CE2-CD1 3.62Å; F35-Y77 HydrophobicContact CE2-CD1 3.62Å; F35-Y77 AromaticContact CE2-CE1 3.34Å; F35-Y77 HydrophobicContact CE2-CE1 3.34Å; F35-Y77 HydrophobicContact CG-CE1 4.09Å; F35-Y77 HydrophobicContact CZ-CD1 4.1Å; F35-Y77 AromaticContact CZ-CE1 3.95Å; F35-Y77 HydrophobicContact CZ-CE1 3.95Å; F35-I193 HydrophobicContact CE1-CB 4.27Å; F35-I193 HydrophobicContact CE1-CG1 4.11Å; F35-I193 HydrophobicContact CE1-CG2 4.3Å; F35-I193 HydrophobicContact CZ-CG1 4.14Å; F35-I193 HydrophobicContact CZ-CG2 4.47Å
36Y88.9Confident85.9Confident39 Ų3945.9 Ų45.915%0.15324%0.243CC..Hα-helixtrans-66-52.8-176.6-179.4-116000111.1D34 A38 F39 L40 K199 E203D34-Y36 VanDerWaalsContact C-N 3.29Å; D34-Y36 PolarHBondContact O-N 3.12Å; D34-Y36 WeakPolarHBondContact OD1-CB 3.37Å; D34-Y36 PolarHBondContact OD1-N 3Å; Y36-A38 VanDerWaalsContact C-N 3.32Å; Y36-A38 PolarHBondContact O-N 2.68Å; Y36-F39 WeakPolarHBondContact O-CB 3.41Å; Y36-F39 PolarHBondContact O-N 2.85Å; Y36-L40 HydrophobicContact CD1-CD1 4.2Å; Y36-L40 HydrophobicContact CD2-CG 4.4Å; Y36-L40 HydrophobicContact CE1-CD1 3.63Å; Y36-L40 HydrophobicContact CE1-CG 4.37Å; Y36-L40 HydrophobicContact CE2-CD1 4.15Å; Y36-L40 HydrophobicContact CE2-CD2 4.1Å; Y36-L40 HydrophobicContact CE2-CG 4.11Å; Y36-L40 WeakPolarHBondContact O-CG 3.35Å; Y36-L40 PolarHBondContact O-N 3.24Å; Y36-K199 HydrophobicContact CE1-CD 4.31Å; Y36-K199 HydrophobicContact CE2-CB 4.12Å; Y36-K199 HydrophobicContact CE2-CD 4.18Å; Y36-K199 HydrophobicContact CE2-CG 4.13Å; Y36-E203 PolarHBondContact OH-OE2 2.73Å
37T88Confident86.5Confident89 Ų8945.5 Ų45.555%0.54624%0.24SC..Hα-helixtrans-58.1-43.4176-58.90000112D34 F39 L40 H41D34-T37 WeakPolarHBondContact OD2-CB 3.11Å; D34-T37 PolarHBondContact OD2-N 3.23Å; D34-T37 PolarHBondContact OD2-OG1 3.04Å; T37-F39 VanDerWaalsContact C-N 3.35Å; T37-F39 PolarHBondContact O-N 3.48Å; T37-L40 PolarHBondContact O-N 3.06Å; T37-H41 WeakPolarHBondContact O-CB 3.43Å; T37-H41 PolarHBondContact O-N 3.48Å
38A88.7Confident87Confident8 Ų843.2 Ų43.27%0.06622%0.224CC..Hα-helixtrans-66.9-33.9178.200000113.5W28 Q32 D34 F35 Y36 H42W28-A38 HydrophobicContact CH2-CB 3.95Å; W28-A38 HydrophobicContact CZ3-CB 4.08Å; Q32-A38 HydrophobicContact CB-CB 3.99Å; Q32-A38 HydrophobicContact CG-CB 3.65Å; D34-A38 PolarHBondContact O-N 2.96Å; F35-A38 PolarHBondContact O-N 2.68Å; Y36-A38 VanDerWaalsContact C-N 3.32Å; Y36-A38 PolarHBondContact O-N 2.68Å; A38-H42 PolarHBondContact O-N 2.9Å
39F90.9Very high87.1Confident0 Ų045.5 Ų45.50%024%0.237CC..Hα-helixtrans-69.2-49.4175179-119.1000111W29 F35 Y36 T37 H41 H42 L43 L74 V197 L317W29-F39 HydrophobicContact CZ2-CD2 4.21Å; F35-F39 HydrophobicContact CE1-CB 4.23Å; F35-F39 HydrophobicContact CE1-CG 4.36Å; F35-F39 HydrophobicContact CE2-CB 4.4Å; F35-F39 HydrophobicContact CZ-CB 4.12Å; F35-F39 HydrophobicContact CZ-CD2 4.17Å; F35-F39 HydrophobicContact CZ-CG 4.2Å; F35-F39 WeakPolarHBondContact O-CB 3.2Å; F35-F39 PolarHBondContact O-N 3.06Å; Y36-F39 WeakPolarHBondContact O-CB 3.41Å; Y36-F39 PolarHBondContact O-N 2.85Å; T37-F39 VanDerWaalsContact C-N 3.35Å; T37-F39 PolarHBondContact O-N 3.48Å; F39-H41 VanDerWaalsContact C-N 3.33Å; F39-H41 PolarHBondContact O-N 2.85Å; F39-H42 WeakPolarHBondContact O-CB 3.35Å; F39-H42 PolarHBondContact O-N 3Å; F39-H42 VanDerWaalsContact O-N 3.16Å; F39-L43 HydrophobicContact CD1-CD1 4.12Å; F39-L43 HydrophobicContact CD2-CG 4.36Å; F39-L43 HydrophobicContact CE1-CD1 3.61Å; F39-L43 HydrophobicContact CE1-CG 4.34Å; F39-L43 HydrophobicContact CE2-CD1 4.15Å; F39-L43 HydrophobicContact CE2-CD2 3.98Å; F39-L43 HydrophobicContact CE2-CG 4.07Å; F39-L43 HydrophobicContact CZ-CD1 3.63Å; F39-L43 HydrophobicContact CZ-CD2 4.14Å; F39-L43 HydrophobicContact CZ-CG 4.08Å; F39-L43 WeakPolarHBondContact O-CG 3.42Å; F39-L43 PolarHBondContact O-N 2.91Å; F39-L74 HydrophobicContact CD2-CD2 4.29Å; F39-L74 HydrophobicContact CE2-CD1 4.02Å; F39-L74 HydrophobicContact CE2-CD2 3.91Å; F39-L74 HydrophobicContact CE2-CG 4.38Å; F39-L74 HydrophobicContact CZ-CD1 4.41Å; F39-V197 HydrophobicContact CE1-CG2 4.05Å; F39-V197 HydrophobicContact CZ-CG2 4Å; F39-L317 HydrophobicContact CZ-CD2 4.11Å
40L91.2Very high87.4Confident6 Ų646.2 Ų46.23%0.03124%0.24CC..Hα-helixtrans-57.4-44.8175.5-67.3-172.9000112Y36 T37 H42 L43 A44 Y200 E216 L217Y36-L40 HydrophobicContact CD1-CD1 4.2Å; Y36-L40 HydrophobicContact CD2-CG 4.4Å; Y36-L40 HydrophobicContact CE1-CD1 3.63Å; Y36-L40 HydrophobicContact CE1-CG 4.37Å; Y36-L40 HydrophobicContact CE2-CD1 4.15Å; Y36-L40 HydrophobicContact CE2-CD2 4.1Å; Y36-L40 HydrophobicContact CE2-CG 4.11Å; Y36-L40 WeakPolarHBondContact O-CG 3.35Å; Y36-L40 PolarHBondContact O-N 3.24Å; T37-L40 PolarHBondContact O-N 3.06Å; L40-H42 VanDerWaalsContact C-N 3.3Å; L40-H42 PolarHBondContact O-N 3.42Å; L40-L43 PolarHBondContact O-N 2.96Å; L40-A44 WeakPolarHBondContact O-CB 3.18Å; L40-A44 PolarHBondContact O-N 3.3Å; L40-Y200 HydrophobicContact CD2-CD2 3.58Å; L40-Y200 HydrophobicContact CD2-CE2 4.42Å; L40-Y200 HydrophobicContact CD2-CG 4.4Å; L40-E216 HydrophobicContact CD1-CB 3.58Å; L40-E216 HydrophobicContact CD1-CG 4.07Å; L40-L217 HydrophobicContact CB-CD2 4.12Å; L40-L217 HydrophobicContact CD2-CD2 4.19Å; L40-L217 WeakPolarHBondContact O-CD2 3.5Å
41H87.8Confident87.8Confident71 Ų7142.6 Ų42.633%0.32922%0.221SC..Hα-helixtrans-60.5-38177.8-175.7-80.3000112.6T37 F39 Q45 I219T37-H41 WeakPolarHBondContact O-CB 3.43Å; T37-H41 PolarHBondContact O-N 3.48Å; F39-H41 VanDerWaalsContact C-N 3.33Å; F39-H41 PolarHBondContact O-N 2.85Å; H41-Q45 PolarHBondContact CE1-NE2 2.99Å; H41-I219 HydrophobicContact CB-CD1 4.1Å; H41-I219 VanDerWaalsContact CD2-CD1 3.48Å; H41-I219 WeakPolarHBondContact CD2-CD1 3.46Å
42H90.1Very high87.6Confident5 Ų541.4 Ų41.42%0.02321%0.213CC..Hα-helixtrans-67.6-44.2174-172.771.4000112.1L18 L25 W29 A38 F39 L40 Q45 L46 S69L18-H42 WeakPolarHBondContact CD2-ND1 3.33Å; L25-H42 WeakPolarHBondContact CD2-CE1 3.44Å; L25-H42 WeakPolarHBondContact CD2-NE2 3.45Å; W29-H42 HydrophobicContact CZ2-CB 4.21Å; W29-H42 AromaticContact CZ2-CD2 3.59Å; W29-H42 AromaticContact CZ2-CG 3.9Å; A38-H42 PolarHBondContact O-N 2.9Å; F39-H42 WeakPolarHBondContact O-CB 3.35Å; F39-H42 PolarHBondContact O-N 3Å; F39-H42 VanDerWaalsContact O-N 3.16Å; L40-H42 VanDerWaalsContact C-N 3.3Å; L40-H42 PolarHBondContact O-N 3.42Å; H42-Q45 PolarHBondContact O-N 3.33Å; H42-L46 VanDerWaalsContact CE1-CD1 3.42Å; H42-L46 WeakPolarHBondContact CE1-CD1 3.3Å; H42-L46 WeakPolarHBondContact NE2-CD1 3.43Å; H42-L46 PolarHBondContact O-N 3.39Å; H42-S69 PolarHBondContact NE2-O 3.46Å; H42-S69 VanDerWaalsContact NE2-O 3.17Å
43L92.6Very high87.3Confident0 Ų039.6 Ų39.60%021%0.209CC..Hα-helixtrans-63.6-44178.7-67.3-171.6000112.6F39 L40 Q45 L46 V47 I70 Y200 F313F39-L43 HydrophobicContact CD1-CD1 4.12Å; F39-L43 HydrophobicContact CD2-CG 4.36Å; F39-L43 HydrophobicContact CE1-CD1 3.61Å; F39-L43 HydrophobicContact CE1-CG 4.34Å; F39-L43 HydrophobicContact CE2-CD1 4.15Å; F39-L43 HydrophobicContact CE2-CD2 3.98Å; F39-L43 HydrophobicContact CE2-CG 4.07Å; F39-L43 HydrophobicContact CZ-CD1 3.63Å; F39-L43 HydrophobicContact CZ-CD2 4.14Å; F39-L43 HydrophobicContact CZ-CG 4.08Å; F39-L43 WeakPolarHBondContact O-CG 3.42Å; F39-L43 PolarHBondContact O-N 2.91Å; L40-L43 PolarHBondContact O-N 2.96Å; L43-Q45 PolarHBondContact O-N 3.02Å; L43-Q45 VanDerWaalsContact O-N 3.12Å; L43-L46 PolarHBondContact O-N 3.21Å; L43-V47 HydrophobicContact CB-CG2 4.08Å; L43-V47 HydrophobicContact CD2-CG2 4Å; L43-V47 VanDerWaalsContact O-CB 3.26Å; L43-V47 WeakPolarHBondContact O-CB 3.31Å; L43-V47 WeakPolarHBondContact O-CG2 3.46Å; L43-V47 PolarHBondContact O-N 3.12Å; L43-I70 HydrophobicContact CD2-CD1 3.88Å; L43-I70 HydrophobicContact CD2-CG2 4Å; L43-Y200 HydrophobicContact CD1-CD1 4.07Å; L43-Y200 HydrophobicContact CD1-CD2 3.67Å; L43-Y200 HydrophobicContact CD1-CE1 4.01Å; L43-Y200 HydrophobicContact CD1-CE2 3.55Å; L43-Y200 HydrophobicContact CD1-CG 3.93Å; L43-F313 HydrophobicContact CD1-CD1 4.41Å; L43-F313 HydrophobicContact CD1-CE1 3.79Å; L43-F313 HydrophobicContact CD2-CD1 4.29Å; L43-F313 HydrophobicContact CD2-CE1 3.44Å; L43-F313 VanDerWaalsContact CD2-CE1 3.44Å; L43-F313 HydrophobicContact CD2-CZ 3.88Å; L43-F313 HydrophobicContact CG-CE1 4.24Å
44A89.7Confident87.2Confident2 Ų233 Ų332%0.01717%0.167CC..Hα-helixtrans-58-24.5178.900000113.5L40 L217 I219L40-A44 WeakPolarHBondContact O-CB 3.18Å; L40-A44 PolarHBondContact O-N 3.3Å; A44-L217 HydrophobicContact CB-CB 4.38Å; A44-L217 HydrophobicContact CB-CD2 3.88Å; A44-I219 HydrophobicContact CB-CB 4.26Å; A44-I219 HydrophobicContact CB-CD1 3.58Å; A44-I219 HydrophobicContact CB-CG1 3.74Å
45Q87.1Confident86.7Confident51 Ų5132 Ų3224%0.23816%0.161CC..Hα-helixtrans-86.7-49.1175.6-63.3-171.310.700112.1L18 H41 H42 L43 R220L18-Q45 VanDerWaalsContact CD1-OE1 3.26Å; H41-Q45 PolarHBondContact CE1-NE2 2.99Å; H42-Q45 PolarHBondContact O-N 3.33Å; L43-Q45 PolarHBondContact O-N 3.02Å; L43-Q45 VanDerWaalsContact O-N 3.12Å; Q45-R220 VanDerWaalsContact O-CZ 3.25Å; Q45-R220 PolarHBondContact O-NH2 3.46Å
46L90.3Very high85.9Confident32 Ų3238.3 Ų38.317%0.16820%0.196CC..Hα-helixtrans-85.3-35.5-171.2-64.9-174.8000114.8H42 L43 E49 I50 I70H42-L46 VanDerWaalsContact CE1-CD1 3.42Å; H42-L46 WeakPolarHBondContact CE1-CD1 3.3Å; H42-L46 WeakPolarHBondContact NE2-CD1 3.43Å; H42-L46 PolarHBondContact O-N 3.39Å; L43-L46 PolarHBondContact O-N 3.21Å; L46-E49 PolarHBondContact O-N 2.95Å; L46-I50 HydrophobicContact CB-CD1 4.24Å; L46-I50 WeakPolarHBondContact O-CG1 3.41Å; L46-I50 PolarHBondContact O-N 3.29Å; L46-I70 HydrophobicContact CB-CD1 4.28Å; L46-I70 HydrophobicContact CD1-CD1 4.49Å; L46-I70 HydrophobicContact CD1-CG1 4.02Å
47V92.1Very high85.4Confident0 Ų038.2 Ų38.20%020%0.199CC..Hα-helixtrans-63.9-43.9-171.3171.80000112.2L43 E49 I50 Y51 I70 A309 H310 F313L43-V47 HydrophobicContact CB-CG2 4.08Å; L43-V47 HydrophobicContact CD2-CG2 4Å; L43-V47 VanDerWaalsContact O-CB 3.26Å; L43-V47 WeakPolarHBondContact O-CB 3.31Å; L43-V47 WeakPolarHBondContact O-CG2 3.46Å; L43-V47 PolarHBondContact O-N 3.12Å; V47-E49 VanDerWaalsContact C-N 3.26Å; V47-E49 PolarHBondContact O-N 3.12Å; V47-I50 PolarHBondContact O-N 3Å; V47-Y51 HydrophobicContact CG1-CD2 4.13Å; V47-Y51 PolarHBondContact O-N 3.34Å; V47-Y51 VanDerWaalsContact O-N 3.13Å; V47-I70 HydrophobicContact CG2-CD1 4.04Å; V47-A309 HydrophobicContact CG1-CB 4.26Å; V47-H310 HydrophobicContact CG1-CB 4.4Å; V47-F313 HydrophobicContact CG1-CB 3.62Å; V47-F313 HydrophobicContact CG1-CD1 4.34Å; V47-F313 HydrophobicContact CG1-CG 4.12Å; V47-F313 HydrophobicContact CG2-CB 4.2Å; V47-F313 HydrophobicContact CG2-CD1 3.52Å; V47-F313 HydrophobicContact CG2-CD2 4.39Å; V47-F313 HydrophobicContact CG2-CE1 4.04Å; V47-F313 HydrophobicContact CG2-CG 3.75Å
48P89.2Confident85.2Confident16 Ų1638.3 Ų38.310%0.10420%0.197CC..Hα-helixtrans-60.3-30.6171.4-27.237.8000114.4F52 E306P48-F52 WeakPolarHBondContact O-CA 3.27Å; P48-F52 VanDerWaalsContact O-CB 3.26Å; P48-F52 WeakPolarHBondContact O-CB 3.5Å; P48-F52 PolarHBondContact O-N 2.91Å; P48-E306 HydrophobicContact CB-CG 4.14Å; P48-E306 HydrophobicContact CG-CB 4.31Å; P48-E306 HydrophobicContact CG-CG 4.23Å
49E87.1Confident85Confident102 Ų10243.3 Ų43.348%0.47722%0.222SC..Hα-helixtrans-79.5-33.1-179.6-67.2-174.9176.800113.2L46 V47 F52 R220L46-E49 PolarHBondContact O-N 2.95Å; V47-E49 VanDerWaalsContact C-N 3.26Å; V47-E49 PolarHBondContact O-N 3.12Å; E49-F52 WeakPolarHBondContact O-CD1 3.3Å; E49-R220 IonicContact OE1-CZ 2.75Å; E49-R220 IonicContact OE1-NH1 3.8Å; E49-R220 PolarHBondContact OE1-NH1 3.15Å; E49-R220 IonicContact OE1-NH2 3.34Å; E49-R220 PolarHBondContact OE1-NH2 3.36Å
50I88.8Confident84.7Confident16 Ų1651 Ų518%0.08226%0.258CS..Hα-helixtrans-74.4-45.4177.6-64.9165.3000110.1L46 V47 Q62 V66 I70L46-I50 HydrophobicContact CB-CD1 4.24Å; L46-I50 WeakPolarHBondContact O-CG1 3.41Å; L46-I50 PolarHBondContact O-N 3.29Å; V47-I50 PolarHBondContact O-N 3Å; I50-Q62 HydrophobicContact CG2-CB 4.49Å; I50-Q62 PolarHBondContact O-NE2 3.17Å; I50-V66 HydrophobicContact CD1-CB 4.37Å; I50-V66 HydrophobicContact CG2-CB 4.4Å; I50-I70 HydrophobicContact CD1-CD1 4.04Å
51Y87.3Confident84.6Confident5 Ų556.5 Ų56.52%0.0228%0.281CS..SBendtrans-102.328.6-174.1-57.3-75.1000113.6V47 A53 Q62 K312 F313V47-Y51 HydrophobicContact CG1-CD2 4.13Å; V47-Y51 PolarHBondContact O-N 3.34Å; V47-Y51 VanDerWaalsContact O-N 3.13Å; Y51-A53 PolarHBondContact O-N 2.88Å; Y51-A53 VanDerWaalsContact O-N 3.13Å; Y51-Q62 HydrophobicContact CD1-CG 4.41Å; Y51-Q62 HydrophobicContact CE1-CB 4.33Å; Y51-K312 HydrophobicContact CD1-CD 3.78Å; Y51-K312 HydrophobicContact CD1-CG 4.21Å; Y51-K312 HydrophobicContact CE1-CD 4.28Å; Y51-K312 HydrophobicContact CE1-CG 4.36Å; Y51-K312 HydrophobicContact CG-CD 4.43Å; Y51-F313 HydrophobicContact CD2-CB 4.15Å; Y51-F313 HydrophobicContact CE2-CB 3.73Å; Y51-F313 AromaticContact CE2-CD2 3.9Å; Y51-F313 HydrophobicContact CE2-CD2 3.9Å; Y51-F313 HydrophobicContact CE2-CG 4.19Å
52F76.3Confident84.6Confident122 Ų12253.8 Ų53.854%0.53527%0.269SS..  trans-68.1-7.9-177.682.3-76000115.6P48 E49 R225 Y227P48-F52 WeakPolarHBondContact O-CA 3.27Å; P48-F52 VanDerWaalsContact O-CB 3.26Å; P48-F52 WeakPolarHBondContact O-CB 3.5Å; P48-F52 PolarHBondContact O-N 2.91Å; E49-F52 WeakPolarHBondContact O-CD1 3.3Å; F52-R225 PolarHBondContact O-NH1 3.36Å; F52-Y227 PolarHBondContact O-OH 3.3Å
53A75.7Confident84.6Confident23 Ų2356.9 Ų56.919%0.1928%0.283CS..  trans-131.263.2-16600000112.6Y51 M55 D56 P57Y51-A53 PolarHBondContact O-N 2.88Å; Y51-A53 VanDerWaalsContact O-N 3.13Å; A53-M55 PolarHBondContact O-N 3.32Å; A53-D56 CarbonylContact O-C 3.53Å; A53-P57 VanDerWaalsContact O-CA 3.31Å; A53-P57 WeakPolarHBondContact O-CA 3.3Å; A53-P57 WeakPolarHBondContact O-CB 3.46Å
54E75.4Confident84.4Confident18 Ų1863.4 Ų63.48%0.08431%0.314CS..  trans-76.6-18-174.3-72.3-56.7119.900115.8Y227 M308 K312E54-Y227 HydrophobicContact CB-CE1 4.23Å; E54-Y227 HydrophobicContact CB-CE2 4.15Å; E54-Y227 HydrophobicContact CG-CE2 4.28Å; E54-Y227 PolarHBondContact N-OH 2.91Å; E54-M308 HydrophobicContact CB-CE 4.02Å; E54-M308 HydrophobicContact CB-SD 4.21Å; E54-M308 HydrophobicContact CG-CE 4.07Å; E54-M308 HydrophobicContact CG-CG 4.25Å; E54-M308 HydrophobicContact CG-SD 4.13Å; E54-K312 VanDerWaalsContact OE1-CD 3.22Å; E54-K312 WeakPolarHBondContact OE1-CD 3.42Å; E54-K312 WeakPolarHBondContact OE1-CE 3.38Å; E54-K312 IonicContact OE1-NZ 3.87Å; E54-K312 PolarHBondContact OE1-NZ 3.22Å; E54-K312 VanDerWaalsContact OE2-CD 3.26Å; E54-K312 WeakPolarHBondContact OE2-CD 3.39Å; E54-K312 IonicContact OE2-NZ 3.35Å; E54-K312 PolarHBondContact OE2-NZ 3.01Å
55M74Confident84.4Confident55 Ų5565.2 Ų65.227%0.27133%0.326SS..SBendtrans-72.8-38.4177.3-71.7-63.8-57.700112.5A53 Y227 A270 A273A53-M55 PolarHBondContact O-N 3.32Å; M55-Y227 HydrophobicContact CG-CD1 4.49Å; M55-Y227 HydrophobicContact CG-CE1 4.21Å; M55-A270 HydrophobicContact SD-CB 3.86Å; M55-A270 VanDerWaalsContact SD-O 3.41Å; M55-A273 HydrophobicContact CG-CB 3.76Å; M55-A273 HydrophobicContact SD-CB 4.4Å
56D72.5Confident84.6Confident145 Ų14562.8 Ų62.878%0.77532%0.315SS*.SBendtrans-142.477.4-178.6-171.422.3000109.2A53A53-D56 CarbonylContact O-C 3.53Å
57P78.3Confident84.7Confident36 Ų3663.7 Ų63.723%0.23432%0.318CS..  trans-82124.6-173.930.5-33.2000112A53 L59A53-P57 VanDerWaalsContact O-CA 3.31Å; A53-P57 WeakPolarHBondContact O-CA 3.3Å; A53-P57 WeakPolarHBondContact O-CB 3.46Å; P57-L59 VanDerWaalsContact C-N 3.31Å; P57-L59 HydrophobicContact CB-CD2 4.11Å; P57-L59 HydrophobicContact CG-CD2 4.05Å; P57-L59 HydrophobicContact CG-CG 4.43Å; P57-L59 PolarHBondContact O-N 2.9Å
58D83.7Confident84.5Confident91 Ų9169.1 Ų69.149%0.48735%0.345SS..  trans-70.787.7162.7-177.6-13.3000109.1E60 K61 Q62D58-E60 VanDerWaalsContact C-N 3.33Å; D58-E60 PolarHBondContact O-N 3.04Å; D58-K61 HydrophobicContact CB-CB 4.09Å; D58-K61 PolarHBondContact O-N 3.37Å; D58-K61 WeakPolarHBondContact OD1-CB 3.39Å; D58-K61 PolarHBondContact OD1-N 2.88Å; D58-K61 VanDerWaalsContact OD1-N 3.1Å; D58-K61 VanDerWaalsContact OD2-CB 3.24Å; D58-K61 WeakPolarHBondContact OD2-CB 3.5Å; D58-K61 WeakPolarHBondContact OD2-CD 3.44Å; D58-Q62 WeakPolarHBondContact O-CB 3.12Å; D58-Q62 WeakPolarHBondContact O-CG 3.36Å; D58-Q62 PolarHBondContact O-N 3.47Å
59L84.6Confident84.5Confident114 Ų11470.4 Ų70.460%0.59735%0.354SS*.Hα-helixtrans-62.9-36.2-172.6-66.7175.1000113P57 E63P57-L59 VanDerWaalsContact C-N 3.31Å; P57-L59 HydrophobicContact CB-CD2 4.11Å; P57-L59 HydrophobicContact CG-CD2 4.05Å; P57-L59 HydrophobicContact CG-CG 4.43Å; P57-L59 PolarHBondContact O-N 2.9Å; L59-E63 WeakPolarHBondContact O-CB 3.34Å; L59-E63 PolarHBondContact O-N 2.83Å
60E86.1Confident84.7Confident160 Ų16065.5 Ų65.575%0.74833%0.332SS*.Hα-helixtrans-66.8-48.5178.6-66.9-174.6167.500110D58 Q62 E63 E64D58-E60 VanDerWaalsContact C-N 3.33Å; D58-E60 PolarHBondContact O-N 3.04Å; E60-Q62 PolarHBondContact O-N 3.32Å; E60-E63 PolarHBondContact O-N 3.21Å; E60-E64 PolarHBondContact O-N 3Å
61K87.4Confident85Confident122 Ų12265 Ų6553%0.5333%0.329SS..Hα-helixtrans-65.7-36.8177-174-179.2176.1-174.80113.2D58 E63 S65D58-K61 HydrophobicContact CB-CB 4.09Å; D58-K61 PolarHBondContact O-N 3.37Å; D58-K61 WeakPolarHBondContact OD1-CB 3.39Å; D58-K61 PolarHBondContact OD1-N 2.88Å; D58-K61 VanDerWaalsContact OD1-N 3.1Å; D58-K61 VanDerWaalsContact OD2-CB 3.24Å; D58-K61 WeakPolarHBondContact OD2-CB 3.5Å; D58-K61 WeakPolarHBondContact OD2-CD 3.44Å; K61-E63 VanDerWaalsContact C-N 3.32Å; K61-S65 VanDerWaalsContact O-CB 3.23Å; K61-S65 WeakPolarHBondContact O-CB 3.3Å; K61-S65 PolarHBondContact O-N 3.48Å; K61-S65 PolarHBondContact O-OG 3.15Å
62Q88.6Confident85.1Confident14 Ų1466 Ų667%0.06534%0.335CS..Hα-helixtrans-60.6-43.7173.4-78.6-173.4-9.600110.8I50 Y51 D58 E60 S65 V66I50-Q62 HydrophobicContact CG2-CB 4.49Å; I50-Q62 PolarHBondContact O-NE2 3.17Å; Y51-Q62 HydrophobicContact CD1-CG 4.41Å; Y51-Q62 HydrophobicContact CE1-CB 4.33Å; D58-Q62 WeakPolarHBondContact O-CB 3.12Å; D58-Q62 WeakPolarHBondContact O-CG 3.36Å; D58-Q62 PolarHBondContact O-N 3.47Å; E60-Q62 PolarHBondContact O-N 3.32Å; Q62-S65 PolarHBondContact O-N 3.18Å; Q62-V66 WeakPolarHBondContact O-CG1 3.46Å; Q62-V66 PolarHBondContact O-N 2.61Å
63E88.9Confident85.8Confident70 Ų7060.2 Ų60.233%0.32731%0.31SS..Hα-helixtrans-68.2-45179.7-167.367.7-177.800112.3L59 E60 K61 S65 V66 Q67 R316L59-E63 WeakPolarHBondContact O-CB 3.34Å; L59-E63 PolarHBondContact O-N 2.83Å; E60-E63 PolarHBondContact O-N 3.21Å; K61-E63 VanDerWaalsContact C-N 3.32Å; E63-S65 VanDerWaalsContact C-N 3.32Å; E63-S65 PolarHBondContact O-N 3.2Å; E63-V66 WeakPolarHBondContact O-CG1 3.48Å; E63-Q67 VanDerWaalsContact O-CB 3.23Å; E63-Q67 WeakPolarHBondContact O-CB 3.42Å; E63-Q67 PolarHBondContact O-N 3.37Å; E63-R316 IonicContact OE1-CZ 3.92Å; E63-R316 IonicContact OE1-NH2 3.08Å; E63-R316 PolarHBondContact OE1-NH2 3.47Å; E63-R316 IonicContact OE2-CZ 3.31Å; E63-R316 IonicContact OE2-NE 3.2Å; E63-R316 PolarHBondContact OE2-NE 3.29Å; E63-R316 IonicContact OE2-NH2 3.88Å; E63-R316 PolarHBondContact OE2-NH2 2.99Å
64E88.9Confident86.6Confident138 Ų13859.1 Ų59.165%0.64530%0.301SS*.Hα-helixtrans-59.1-43.3173.4-72.1-172.5163.300111.7E60 M68E60-E64 PolarHBondContact O-N 3Å; E64-M68 WeakPolarHBondContact O-CB 3.4Å; E64-M68 WeakPolarHBondContact O-CG 3.12Å; E64-M68 PolarHBondContact O-N 3.23Å
65S89.7Confident87.4Confident39 Ų3958.7 Ų58.727%0.27330%0.299SS..Hα-helixtrans-66.7-44.3-177.9-59.20000112.4K61 Q62 E63 S69K61-S65 VanDerWaalsContact O-CB 3.23Å; K61-S65 WeakPolarHBondContact O-CB 3.3Å; K61-S65 PolarHBondContact O-N 3.48Å; K61-S65 PolarHBondContact O-OG 3.15Å; Q62-S65 PolarHBondContact O-N 3.18Å; E63-S65 VanDerWaalsContact C-N 3.32Å; E63-S65 PolarHBondContact O-N 3.2Å; S65-S69 WeakPolarHBondContact O-CB 3.23Å; S65-S69 PolarHBondContact O-N 3.15Å; S65-S69 PolarHBondContact O-OG 2.91Å
66V92.3Very high88.1Confident0 Ų058.2 Ų58.20%029%0.294CS..Hα-helixtrans-70.8-37.9177.872.20000112I50 Q62 E63 I70 F71 F313I50-V66 HydrophobicContact CD1-CB 4.37Å; I50-V66 HydrophobicContact CG2-CB 4.4Å; Q62-V66 WeakPolarHBondContact O-CG1 3.46Å; Q62-V66 PolarHBondContact O-N 2.61Å; E63-V66 WeakPolarHBondContact O-CG1 3.48Å; V66-I70 HydrophobicContact CG2-CB 4.38Å; V66-I70 HydrophobicContact CG2-CD1 4.26Å; V66-I70 PolarHBondContact O-N 3.3Å; V66-F71 HydrophobicContact CB-CE2 4.4Å; V66-F71 HydrophobicContact CG1-CD2 4.18Å; V66-F71 HydrophobicContact CG1-CE2 3.73Å; V66-F71 HydrophobicContact CG1-CZ 4.46Å; V66-F71 HydrophobicContact CG2-CD2 4.27Å; V66-F71 HydrophobicContact CG2-CE1 4.34Å; V66-F71 HydrophobicContact CG2-CE2 3.82Å; V66-F71 HydrophobicContact CG2-CZ 3.85Å; V66-F71 PolarHBondContact O-N 2.71Å; V66-F313 HydrophobicContact CG2-CD2 3.84Å; V66-F313 HydrophobicContact CG2-CE2 3.51Å
67Q91.4Very high88.9Confident51 Ų5151.9 Ų51.924%0.23826%0.26CS..Iπ-helixtrans-62.9-50176.2-177.262.95400110.4E63 T72E63-Q67 VanDerWaalsContact O-CB 3.23Å; E63-Q67 WeakPolarHBondContact O-CB 3.42Å; E63-Q67 PolarHBondContact O-N 3.37Å; Q67-T72 PolarHBondContact NE2-OG1 3.02Å; Q67-T72 VanDerWaalsContact O-CB 3.25Å; Q67-T72 WeakPolarHBondContact O-CB 3.45Å; Q67-T72 PolarHBondContact O-N 3.13Å; Q67-T72 PolarHBondContact O-OG1 3.4Å
68M88.9Confident89.5Confident114 Ų11450.1 Ų50.156%0.56225%0.248SC*.Iπ-helixtrans-69.4-37.3-178.7-74.2-59.9-59.900114.1E64 P73E64-M68 WeakPolarHBondContact O-CB 3.4Å; E64-M68 WeakPolarHBondContact O-CG 3.12Å; E64-M68 PolarHBondContact O-N 3.23Å; M68-P73 WeakPolarHBondContact O-CD 3.49Å
69S88.8Confident89.7Confident43 Ų4346.3 Ų46.330%0.30123%0.228SC..Iπ-helixtrans-98.3-15.5-167.9-40.90000114.4H42 S65H42-S69 PolarHBondContact NE2-O 3.46Å; H42-S69 VanDerWaalsContact NE2-O 3.17Å; S65-S69 WeakPolarHBondContact O-CB 3.23Å; S65-S69 PolarHBondContact O-N 3.15Å; S65-S69 PolarHBondContact O-OG 2.91Å
70I92.1Very high89.7Confident0 Ų044.2 Ų44.20%023%0.234CC..Iπ-helixtrans-133.8-57.3-177.3-50.5-178.8000112.1L43 L46 V47 I50 V66 P73 L74 F313L43-I70 HydrophobicContact CD2-CD1 3.88Å; L43-I70 HydrophobicContact CD2-CG2 4Å; L46-I70 HydrophobicContact CB-CD1 4.28Å; L46-I70 HydrophobicContact CD1-CD1 4.49Å; L46-I70 HydrophobicContact CD1-CG1 4.02Å; V47-I70 HydrophobicContact CG2-CD1 4.04Å; I50-I70 HydrophobicContact CD1-CD1 4.04Å; V66-I70 HydrophobicContact CG2-CB 4.38Å; V66-I70 HydrophobicContact CG2-CD1 4.26Å; V66-I70 PolarHBondContact O-N 3.3Å; I70-P73 WeakPolarHBondContact O-CD 3.02Å; I70-L74 HydrophobicContact CG2-CD1 4.01Å; I70-L74 WeakPolarHBondContact O-CB 3.22Å; I70-L74 WeakPolarHBondContact O-CG 3.48Å; I70-L74 PolarHBondContact O-N 3.44Å; I70-F313 HydrophobicContact CD1-CE2 4Å; I70-F313 HydrophobicContact CD1-CZ 4.01Å; I70-F313 HydrophobicContact CG2-CE2 4.34Å; I70-F313 HydrophobicContact CG2-CZ 3.81Å
71F93.2Very high89.6Confident4 Ų439.7 Ų39.72%0.01821%0.212CC..Iπ-helixtrans-69.6-47.4-173.8-59.7-37000113.4V66 L74 E75 F313 R316 L317 W320V66-F71 HydrophobicContact CB-CE2 4.4Å; V66-F71 HydrophobicContact CG1-CD2 4.18Å; V66-F71 HydrophobicContact CG1-CE2 3.73Å; V66-F71 HydrophobicContact CG1-CZ 4.46Å; V66-F71 HydrophobicContact CG2-CD2 4.27Å; V66-F71 HydrophobicContact CG2-CE1 4.34Å; V66-F71 HydrophobicContact CG2-CE2 3.82Å; V66-F71 HydrophobicContact CG2-CZ 3.85Å; V66-F71 PolarHBondContact O-N 2.71Å; F71-L74 WeakPolarHBondContact O-CB 3.42Å; F71-L74 PolarHBondContact O-N 2.98Å; F71-L74 VanDerWaalsContact O-N 3.11Å; F71-E75 WeakPolarHBondContact O-CB 3.32Å; F71-E75 WeakPolarHBondContact O-CG 3.46Å; F71-E75 PolarHBondContact O-N 3.14Å; F71-F313 AromaticContact CE1-CE2 3.9Å; F71-F313 HydrophobicContact CE1-CE2 3.9Å; F71-F313 HydrophobicContact CE1-CZ 4.29Å; F71-F313 HydrophobicContact CZ-CE2 4.07Å; F71-R316 HydrophobicContact CZ-CB 4.17Å; F71-L317 HydrophobicContact CD1-CD1 4.38Å; F71-L317 HydrophobicContact CE1-CB 4.47Å; F71-L317 HydrophobicContact CE1-CD1 3.85Å; F71-W320 HydrophobicContact CD1-CB 3.97Å; F71-W320 AromaticContact CD1-CD1 3.74Å; F71-W320 HydrophobicContact CD1-CD2 4.11Å; F71-W320 AromaticContact CD1-CG 3.67Å; F71-W320 HydrophobicContact CD1-CG 3.67Å; F71-W320 HydrophobicContact CE1-CB 3.71Å; F71-W320 AromaticContact CE1-CG 3.93Å; F71-W320 HydrophobicContact CE1-CG 3.93Å; F71-W320 HydrophobicContact CE2-CB 4.42Å; F71-W320 HydrophobicContact CG-CB 4.46Å; F71-W320 AromaticContact CG-CD1 3.69Å; F71-W320 HydrophobicContact CG-CG 4.07Å; F71-W320 HydrophobicContact CZ-CB 3.95Å
72T90.4Very high89.4Confident26 Ų2636.6 Ų36.616%0.1620%0.201CC..Hα-helixtrans-59.5-46.3177.2-610000111.3P22 Q67 L74 E75 W76P22-T72 HydrophobicContact CB-CG2 3.99Å; P22-T72 HydrophobicContact CG-CG2 4.18Å; Q67-T72 PolarHBondContact NE2-OG1 3.02Å; Q67-T72 VanDerWaalsContact O-CB 3.25Å; Q67-T72 WeakPolarHBondContact O-CB 3.45Å; Q67-T72 PolarHBondContact O-N 3.13Å; Q67-T72 PolarHBondContact O-OG1 3.4Å; T72-L74 PolarHBondContact O-N 3.47Å; T72-E75 PolarHBondContact O-N 3.24Å; T72-W76 VanDerWaalsContact O-CD1 3.25Å; T72-W76 PolarHBondContact O-N 3.39Å
73P91.1Very high89.2Confident2 Ų236.2 Ų36.21%0.01320%0.2CC..Hα-helixtrans-55.8-42170-25.430.7000114.8P22 L25 W29 M68 I70 W76 Y77P22-P73 HydrophobicContact CB-CB 4.47Å; P22-P73 HydrophobicContact CB-CG 3.9Å; P22-P73 HydrophobicContact CG-CG 4.38Å; L25-P73 HydrophobicContact CB-CB 4.42Å; L25-P73 HydrophobicContact CD2-CB 3.76Å; L25-P73 HydrophobicContact CD2-CG 3.89Å; L25-P73 HydrophobicContact CG-CB 4.35Å; W29-P73 HydrophobicContact CH2-CB 3.98Å; W29-P73 HydrophobicContact CZ3-CB 3.65Å; M68-P73 WeakPolarHBondContact O-CD 3.49Å; I70-P73 WeakPolarHBondContact O-CD 3.02Å; P73-W76 PolarHBondContact O-N 3.41Å; P73-Y77 PolarHBondContact O-N 3.43Å
74L91.6Very high89Confident0 Ų038.7 Ų38.70%022%0.216CC..Hα-helixtrans-64.9-40.5176.7-77.4171.5000111.6W29 F35 F39 I70 F71 T72 Y77 L78 I193 L317 W320W29-L74 HydrophobicContact CH2-CD2 4.09Å; W29-L74 HydrophobicContact CH2-CG 4.15Å; W29-L74 HydrophobicContact CZ3-CD2 3.87Å; W29-L74 HydrophobicContact CZ3-CG 4.05Å; F35-L74 HydrophobicContact CZ-CD2 4.02Å; F39-L74 HydrophobicContact CD2-CD2 4.29Å; F39-L74 HydrophobicContact CE2-CD1 4.02Å; F39-L74 HydrophobicContact CE2-CD2 3.91Å; F39-L74 HydrophobicContact CE2-CG 4.38Å; F39-L74 HydrophobicContact CZ-CD1 4.41Å; I70-L74 HydrophobicContact CG2-CD1 4.01Å; I70-L74 WeakPolarHBondContact O-CB 3.22Å; I70-L74 WeakPolarHBondContact O-CG 3.48Å; I70-L74 PolarHBondContact O-N 3.44Å; F71-L74 WeakPolarHBondContact O-CB 3.42Å; F71-L74 PolarHBondContact O-N 2.98Å; F71-L74 VanDerWaalsContact O-N 3.11Å; T72-L74 PolarHBondContact O-N 3.47Å; L74-Y77 PolarHBondContact O-N 2.94Å; L74-L78 VanDerWaalsContact O-CB 3.24Å; L74-L78 WeakPolarHBondContact O-CB 3.44Å; L74-L78 PolarHBondContact O-N 2.83Å; L74-I193 HydrophobicContact CD2-CG2 4.41Å; L74-L317 HydrophobicContact CD1-CD1 4.2Å; L74-W320 HydrophobicContact CB-CH2 4.03Å; L74-W320 HydrophobicContact CB-CZ2 3.89Å; L74-W320 HydrophobicContact CD1-CH2 4.26Å; L74-W320 HydrophobicContact CD1-CZ3 4.4Å
75E92Very high88.7Confident8 Ų836.3 Ų36.34%0.03721%0.206CC..Hα-helixtrans-64.5-44.1175.8-72170.8174.200110.8F71 T72 Y77 L78 F79 P83 W320 K323 I324F71-E75 WeakPolarHBondContact O-CB 3.32Å; F71-E75 WeakPolarHBondContact O-CG 3.46Å; F71-E75 PolarHBondContact O-N 3.14Å; T72-E75 PolarHBondContact O-N 3.24Å; E75-Y77 VanDerWaalsContact C-N 3.34Å; E75-Y77 PolarHBondContact O-N 3.49Å; E75-L78 PolarHBondContact O-N 3.32Å; E75-F79 HydrophobicContact CB-CD2 4.09Å; E75-F79 HydrophobicContact CB-CE2 3.89Å; E75-F79 HydrophobicContact CG-CE2 4.15Å; E75-F79 WeakPolarHBondContact O-CB 3.24Å; E75-F79 WeakPolarHBondContact O-CD2 3.48Å; E75-F79 WeakPolarHBondContact O-CG 3.34Å; E75-F79 PolarHBondContact O-N 2.95Å; E75-P83 HydrophobicContact CB-CB 4.02Å; E75-P83 HydrophobicContact CB-CG 3.81Å; E75-W320 HydrophobicContact CG-CZ2 3.98Å; E75-W320 PolarHBondContact OE1-NE1 3.04Å; E75-K323 IonicContact OE1-NZ 3.05Å; E75-K323 PolarHBondContact OE1-NZ 3.36Å; E75-I324 HydrophobicContact CG-CD1 4.3Å
76W90.3Very high88.3Confident46 Ų4635 Ų3517%0.17420%0.197CC..Hα-helixtrans-59.8-40.5172.5-86.794.8000112.7Q23 A26 T72 P73 G80 E81 D82 P83Q23-W76 HydrophobicContact CG-CD2 3.67Å; Q23-W76 HydrophobicContact CG-CE3 3.72Å; Q23-W76 HydrophobicContact CG-CG 4.38Å; Q23-W76 HydrophobicContact CG-CH2 3.96Å; Q23-W76 HydrophobicContact CG-CZ2 3.89Å; Q23-W76 HydrophobicContact CG-CZ3 3.85Å; A26-W76 HydrophobicContact CB-CB 3.8Å; T72-W76 VanDerWaalsContact O-CD1 3.25Å; T72-W76 PolarHBondContact O-N 3.39Å; P73-W76 PolarHBondContact O-N 3.41Å; W76-G80 WeakPolarHBondContact O-CA 3.46Å; W76-G80 PolarHBondContact O-N 3.47Å; W76-E81 VanDerWaalsContact CZ3-C 3.42Å; W76-D82 HydrophobicContact CH2-CB 3.6Å; W76-D82 HydrophobicContact CZ2-CB 3.99Å; W76-D82 WeakPolarHBondContact CZ2-OD2 3.22Å; W76-D82 HydrophobicContact CZ3-CB 4.33Å; W76-P83 HydrophobicContact CD2-CG 4.34Å; W76-P83 HydrophobicContact CG-CG 4.06Å
77Y89.5Confident87.7Confident11 Ų1135.4 Ų35.44%0.04320%0.199CC..Hα-helixtrans-71.9-35.4177.9-177.2-133.9000112.6W29 D30 F35 P73 L74 E75 I193W29-Y77 HydrophobicContact CB-CD1 4.27Å; W29-Y77 HydrophobicContact CB-CE1 4.26Å; W29-Y77 HydrophobicContact CB-CG 4.43Å; W29-Y77 HydrophobicContact CE3-CD1 4.34Å; W29-Y77 HydrophobicContact CE3-CG 4.49Å; D30-Y77 HydrophobicContact CB-CD2 4.18Å; D30-Y77 HydrophobicContact CB-CE2 3.59Å; F35-Y77 HydrophobicContact CD2-CD1 4.18Å; F35-Y77 AromaticContact CD2-CE1 3.42Å; F35-Y77 HydrophobicContact CD2-CE1 3.42Å; F35-Y77 VanDerWaalsContact CD2-CE1 3.42Å; F35-Y77 AromaticContact CE2-CD1 3.62Å; F35-Y77 HydrophobicContact CE2-CD1 3.62Å; F35-Y77 AromaticContact CE2-CE1 3.34Å; F35-Y77 HydrophobicContact CE2-CE1 3.34Å; F35-Y77 HydrophobicContact CG-CE1 4.09Å; F35-Y77 HydrophobicContact CZ-CD1 4.1Å; F35-Y77 AromaticContact CZ-CE1 3.95Å; F35-Y77 HydrophobicContact CZ-CE1 3.95Å; P73-Y77 PolarHBondContact O-N 3.43Å; L74-Y77 PolarHBondContact O-N 2.94Å; E75-Y77 VanDerWaalsContact C-N 3.34Å; E75-Y77 PolarHBondContact O-N 3.49Å; Y77-I193 HydrophobicContact CD1-CD1 3.44Å; Y77-I193 VanDerWaalsContact CD1-CD1 3.44Å; Y77-I193 HydrophobicContact CD1-CG1 3.61Å; Y77-I193 HydrophobicContact CE1-CD1 3.84Å; Y77-I193 HydrophobicContact CE1-CG1 3.56Å; Y77-I193 HydrophobicContact CG-CD1 4.12Å
78L89.7Confident87.1Confident0 Ų038.9 Ų38.90%022%0.216CC..Hα-helixtrans-68.9-45.5176.9179.564.8000112.4L74 E75 A190 I193 F194 I324 F331L74-L78 VanDerWaalsContact O-CB 3.24Å; L74-L78 WeakPolarHBondContact O-CB 3.44Å; L74-L78 PolarHBondContact O-N 2.83Å; E75-L78 PolarHBondContact O-N 3.32Å; L78-A190 HydrophobicContact CD1-CB 3.72Å; L78-I193 HydrophobicContact CB-CD1 3.86Å; L78-I193 HydrophobicContact CD1-CD1 3.99Å; L78-F194 HydrophobicContact CD1-CE1 4.01Å; L78-F194 HydrophobicContact CD2-CE1 4.47Å; L78-I324 HydrophobicContact CD2-CD1 4.2Å; L78-I324 HydrophobicContact CD2-CG2 3.91Å; L78-F331 HydrophobicContact CD1-CE1 4.02Å; L78-F331 HydrophobicContact CD2-CE1 4.23Å; L78-F331 HydrophobicContact CD2-CZ 4.21Å; L78-F331 HydrophobicContact CG-CE1 4.35Å; L78-F331 HydrophobicContact CG-CZ 4.47Å
79F88.8Confident86.4Confident11 Ų1138.9 Ų38.95%0.04821%0.212CC..Hα-helixtrans-89.3-25.6-173.3-60.6-51.2000113.6E75 E81 P83 C86 L87 L90 V186 I324 F331E75-F79 HydrophobicContact CB-CD2 4.09Å; E75-F79 HydrophobicContact CB-CE2 3.89Å; E75-F79 HydrophobicContact CG-CE2 4.15Å; E75-F79 WeakPolarHBondContact O-CB 3.24Å; E75-F79 WeakPolarHBondContact O-CD2 3.48Å; E75-F79 WeakPolarHBondContact O-CG 3.34Å; E75-F79 PolarHBondContact O-N 2.95Å; F79-E81 PolarHBondContact O-N 3.2Å; F79-P83 HydrophobicContact CD2-CB 3.92Å; F79-P83 HydrophobicContact CD2-CG 4.24Å; F79-P83 HydrophobicContact CE2-CB 4.16Å; F79-C86 HydrophobicContact CB-CB 3.92Å; F79-C86 HydrophobicContact CD1-CB 4.06Å; F79-C86 VanDerWaalsContact CD1-SG 3.55Å; F79-C86 HydrophobicContact CD2-CB 4.29Å; F79-C86 HydrophobicContact CG-CB 3.84Å; F79-L87 HydrophobicContact CE1-CD2 4.46Å; F79-L87 HydrophobicContact CE2-CD2 4.15Å; F79-L87 HydrophobicContact CE2-CG 4.15Å; F79-L87 HydrophobicContact CZ-CD2 3.68Å; F79-L87 HydrophobicContact CZ-CG 4.16Å; F79-L90 HydrophobicContact CE1-CD1 4.14Å; F79-V186 HydrophobicContact CD1-CG1 4.44Å; F79-I324 HydrophobicContact CZ-CD1 4.26Å; F79-F331 HydrophobicContact CE1-CE2 4.34Å; F79-F331 AromaticContact CE1-CZ 3.98Å; F79-F331 HydrophobicContact CE1-CZ 3.98Å
80G84Confident85.7Confident70 Ų7038 Ų3872%0.72220%0.204SC*.SBendtrans70.2-7.1-176.700000114.9W76W76-G80 WeakPolarHBondContact O-CA 3.46Å; W76-G80 PolarHBondContact O-N 3.47Å
81E83.1Confident84.5Confident64 Ų6444.4 Ų44.430%0.29923%0.232SC..SBendtrans-132.6-173.2173.268174.816600110W76 F79 P83 C86 K89W76-E81 VanDerWaalsContact CZ3-C 3.42Å; F79-E81 PolarHBondContact O-N 3.2Å; E81-P83 WeakPolarHBondContact O-CD 3.39Å; E81-C86 HydrophobicContact CG-CB 3.99Å; E81-K89 IonicContact OE1-NZ 2.68Å; E81-K89 PolarHBondContact OE1-NZ 2.83Å; E81-K89 IonicContact OE2-NZ 2.68Å; E81-K89 PolarHBondContact OE2-NZ 3.42Å
82D84.1Confident82.8Confident57 Ų5751.9 Ų51.931%0.30527%0.267SS..  trans-60.3123.1177.5-166.3-62.3000111.6W76 D84 I85 C86W76-D82 HydrophobicContact CH2-CB 3.6Å; W76-D82 HydrophobicContact CZ2-CB 3.99Å; W76-D82 WeakPolarHBondContact CZ2-OD2 3.22Å; W76-D82 HydrophobicContact CZ3-CB 4.33Å; D82-D84 VanDerWaalsContact C-N 3.31Å; D82-D84 PolarHBondContact O-N 3.04Å; D82-D84 PolarHBondContact OD1-N 3.3Å; D82-I85 HydrophobicContact CB-CB 4.1Å; D82-I85 HydrophobicContact CB-CD1 3.84Å; D82-I85 HydrophobicContact CB-CG1 3.92Å; D82-I85 PolarHBondContact O-N 3.1Å; D82-C86 PolarHBondContact O-N 2.96Å
83P84.9Confident81.2Confident7 Ų753 Ų535%0.04528%0.275CS..Hα-helixtrans-55.2-40.8-178.2-29.736.4000113.9E75 W76 F79 E81 I85 C86 L87E75-P83 HydrophobicContact CB-CB 4.02Å; E75-P83 HydrophobicContact CB-CG 3.81Å; W76-P83 HydrophobicContact CD2-CG 4.34Å; W76-P83 HydrophobicContact CG-CG 4.06Å; F79-P83 HydrophobicContact CD2-CB 3.92Å; F79-P83 HydrophobicContact CD2-CG 4.24Å; F79-P83 HydrophobicContact CE2-CB 4.16Å; E81-P83 WeakPolarHBondContact O-CD 3.39Å; P83-I85 VanDerWaalsContact C-N 3.34Å; P83-I85 PolarHBondContact O-N 2.88Å; P83-C86 PolarHBondContact O-N 3.38Å; P83-L87 VanDerWaalsContact O-CB 3.23Å; P83-L87 WeakPolarHBondContact O-CB 3.39Å; P83-L87 WeakPolarHBondContact O-CG 3.42Å; P83-L87 PolarHBondContact O-N 2.94Å
84D84.6Confident79.4Confident121 Ų12155.4 Ų55.465%0.64730%0.301SS*.Hα-helixtrans-67-40.9-178-75.1-38.2000110.7D82 L87 E88D82-D84 VanDerWaalsContact C-N 3.31Å; D82-D84 PolarHBondContact O-N 3.04Å; D82-D84 PolarHBondContact OD1-N 3.3Å; D84-L87 PolarHBondContact O-N 3.13Å; D84-E88 WeakPolarHBondContact O-CG 3.5Å; D84-E88 PolarHBondContact O-N 3.36Å
85I82.8Confident77.6Confident88 Ų8858.5 Ų58.545%0.45133%0.327SS..Hα-helixtrans-63.8-43.6175.7-61.6-177.8000111D82 P83 K89D82-I85 HydrophobicContact CB-CB 4.1Å; D82-I85 HydrophobicContact CB-CD1 3.84Å; D82-I85 HydrophobicContact CB-CG1 3.92Å; D82-I85 PolarHBondContact O-N 3.1Å; P83-I85 VanDerWaalsContact C-N 3.34Å; P83-I85 PolarHBondContact O-N 2.88Å; I85-K89 WeakPolarHBondContact O-CG 3.41Å; I85-K89 PolarHBondContact O-N 2.91Å
86C80.8Confident76.2Confident11 Ų1162.7 Ų62.77%0.07435%0.345CS..Hα-helixtrans-67.7-44.8179.1-158.50000111.6F79 E81 D82 P83 E88 K89 L90F79-C86 HydrophobicContact CB-CB 3.92Å; F79-C86 HydrophobicContact CD1-CB 4.06Å; F79-C86 VanDerWaalsContact CD1-SG 3.55Å; F79-C86 HydrophobicContact CD2-CB 4.29Å; F79-C86 HydrophobicContact CG-CB 3.84Å; E81-C86 HydrophobicContact CG-CB 3.99Å; D82-C86 PolarHBondContact O-N 2.96Å; P83-C86 PolarHBondContact O-N 3.38Å; C86-E88 VanDerWaalsContact C-N 3.34Å; C86-E88 PolarHBondContact O-N 3.48Å; C86-K89 WeakPolarHBondContact O-CB 3.4Å; C86-K89 PolarHBondContact O-N 3.43Å; C86-K89 VanDerWaalsContact O-N 3.14Å; C86-L90 WeakPolarHBondContact O-CG 3.34Å; C86-L90 PolarHBondContact O-N 3.11Å
87L80.3Confident75.4Confident9 Ų966.9 Ų66.95%0.04737%0.366CS..Hα-helixtrans-64.7-35178.7-70.6176.6000112.4F79 P83 D84 L90 K91 Y327F79-L87 HydrophobicContact CE1-CD2 4.46Å; F79-L87 HydrophobicContact CE2-CD2 4.15Å; F79-L87 HydrophobicContact CE2-CG 4.15Å; F79-L87 HydrophobicContact CZ-CD2 3.68Å; F79-L87 HydrophobicContact CZ-CG 4.16Å; P83-L87 VanDerWaalsContact O-CB 3.23Å; P83-L87 WeakPolarHBondContact O-CB 3.39Å; P83-L87 WeakPolarHBondContact O-CG 3.42Å; P83-L87 PolarHBondContact O-N 2.94Å; D84-L87 PolarHBondContact O-N 3.13Å; L87-L90 HydrophobicContact CD2-CD1 4.4Å; L87-L90 PolarHBondContact O-N 3.36Å; L87-K91 WeakPolarHBondContact O-CB 3.31Å; L87-K91 VanDerWaalsContact O-CG 3.24Å; L87-K91 WeakPolarHBondContact O-CG 3.45Å; L87-K91 PolarHBondContact O-N 3.46Å; L87-Y327 HydrophobicContact CD1-CE2 4.48Å; L87-Y327 HydrophobicContact CD2-CD1 4.19Å; L87-Y327 HydrophobicContact CD2-CD2 3.44Å; L87-Y327 VanDerWaalsContact CD2-CD2 3.44Å; L87-Y327 HydrophobicContact CD2-CE1 4.05Å; L87-Y327 HydrophobicContact CD2-CE2 3.27Å; L87-Y327 HydrophobicContact CD2-CG 3.92Å
88E77.4Confident75Confident125 Ų12568 Ų6858%0.58437%0.373SS*.Hα-helixtrans-63.8-43.2170.6-78.3-162.1159.900112.2D84 C86 L90 K91 H92D84-E88 WeakPolarHBondContact O-CG 3.5Å; D84-E88 PolarHBondContact O-N 3.36Å; C86-E88 VanDerWaalsContact C-N 3.34Å; C86-E88 PolarHBondContact O-N 3.48Å; E88-L90 VanDerWaalsContact C-N 3.31Å; E88-L90 PolarHBondContact O-N 2.96Å; E88-K91 PolarHBondContact O-N 3.48Å; E88-H92 PolarHBondContact O-N 3.49Å; E88-H92 PolarHBondContact O-ND1 3.3Å
89K75.8Confident75Confident113 Ų11369.4 Ų69.449%0.49138%0.382SS..Hα-helixtrans-58.7-43.1175.1-66.2167.1-169.5170.70111.5E81 I85 C86 H92E81-K89 IonicContact OE1-NZ 2.68Å; E81-K89 PolarHBondContact OE1-NZ 2.83Å; E81-K89 IonicContact OE2-NZ 2.68Å; E81-K89 PolarHBondContact OE2-NZ 3.42Å; I85-K89 WeakPolarHBondContact O-CG 3.41Å; I85-K89 PolarHBondContact O-N 2.91Å; C86-K89 WeakPolarHBondContact O-CB 3.4Å; C86-K89 PolarHBondContact O-N 3.43Å; C86-K89 VanDerWaalsContact O-N 3.14Å; K89-H92 PolarHBondContact O-N 3.27Å
90L73.3Confident74.6Confident24 Ų2469.6 Ų69.613%0.12639%0.387CS..Hα-helixtrans-66.5-44.6179.6-65.8172.7000112.4F79 C86 L87 E88 H92 S93 L182 F331F79-L90 HydrophobicContact CE1-CD1 4.14Å; C86-L90 WeakPolarHBondContact O-CG 3.34Å; C86-L90 PolarHBondContact O-N 3.11Å; L87-L90 HydrophobicContact CD2-CD1 4.4Å; L87-L90 PolarHBondContact O-N 3.36Å; E88-L90 VanDerWaalsContact C-N 3.31Å; E88-L90 PolarHBondContact O-N 2.96Å; L90-H92 PolarHBondContact O-N 3.47Å; L90-H92 VanDerWaalsContact O-N 3.13Å; L90-S93 WeakPolarHBondContact O-CB 3.36Å; L90-S93 PolarHBondContact O-N 2.9Å; L90-S93 PolarHBondContact O-OG 3.31Å; L90-L182 HydrophobicContact CD1-CD2 4.41Å; L90-L182 HydrophobicContact CD2-CD2 3.48Å; L90-L182 VanDerWaalsContact CD2-CD2 3.48Å; L90-F331 HydrophobicContact CD1-CE2 4.23Å
91K67.3Low74.7Confident135 Ų13571 Ų7159%0.58737%0.371SS*.Hα-helixtrans-57.3-27.8178.5-76.5167.3-174.4167.80113.8L87 E88L87-K91 WeakPolarHBondContact O-CB 3.31Å; L87-K91 VanDerWaalsContact O-CG 3.24Å; L87-K91 WeakPolarHBondContact O-CG 3.45Å; L87-K91 PolarHBondContact O-N 3.46Å; E88-K91 PolarHBondContact O-N 3.48Å
92H58.3Low74.8Confident162 Ų16270.9 Ų70.975%0.7537%0.374SS*.THydrogen-bonded Turntrans-86.6-5178.5-69.585.6000114.2E88 K89 L90E88-H92 PolarHBondContact O-N 3.49Å; E88-H92 PolarHBondContact O-ND1 3.3Å; K89-H92 PolarHBondContact O-N 3.27Å; L90-H92 PolarHBondContact O-N 3.47Å; L90-H92 VanDerWaalsContact O-N 3.13Å
93S55.2Low74.9Confident48 Ų4868.6 Ų68.634%0.33636%0.361SS..SBendtrans-97.2-2.1-164.972.30000117.1L90L90-S93 WeakPolarHBondContact O-CB 3.36Å; L90-S93 PolarHBondContact O-N 2.9Å; L90-S93 PolarHBondContact O-OG 3.31Å
94G53.8Low74.8Confident53 Ų5376.1 Ų76.155%0.54639%0.394SS..  trans-177.7140.9173.300000116.4
95A53.3Low74.6Confident66 Ų6674.9 Ų74.955%0.54539%0.394SS..  trans-84.8131.6159.700000108.9A171A95-A171 HydrophobicContact CB-CB 4.42Å
96F63.4Low74.7Confident95 Ų9573 Ų7342%0.41740%0.397SS..  trans-68.2138.6177.1-58-72.4000110.6L98 H166 S326F96-L98 WeakPolarHBondContact CB-O 3.49Å; F96-H166 PolarHBondContact O-CD2 3.31Å; F96-S326 WeakPolarHBondContact CZ-O 3.3Å
97Q72.6Confident75.2Confident134 Ų13474.3 Ų74.363%0.62640%0.402SS*.SBendtrans-80-22.5177-66.2179-3.400112.4G152Q97-G152 VanDerWaalsContact O-CA 3.24Å; Q97-G152 WeakPolarHBondContact O-CA 3.41Å
98L82.6Confident75.8Confident36 Ų3676.4 Ų76.419%0.18842%0.415CS..SBendtrans-110.2138.8174.3-73.6164.4000109.5F96 C151 G152 D153 M380F96-L98 WeakPolarHBondContact CB-O 3.49Å; L98-C151 WeakPolarHBondContact CA-O 3.41Å; L98-G152 VanDerWaalsContact CD2-C 3.41Å; L98-D153 HydrophobicContact CD2-CB 4.06Å; L98-M380 HydrophobicContact CB-CE 4.12Å
99C88Confident76.6Confident28 Ų2870.8 Ų70.819%0.18939%0.39CS..  trans-71.6-45.9176.6179.60000112.2R101 C149 C151C99-R101 PolarHBondContact O-N 3.05Å; C99-C149 HydrophobicContact CB-CB 4.14Å; C99-C151 HydrophobicContact CB-CB 3.75Å; C99-C151 PolarHBondContact N-O 2.96Å
100G80.5Confident77.5Confident15 Ų1566 Ų6616%0.15537%0.369CS..  trans62.92.5174.400000116.3V102G100-V102 PolarHBondContact O-N 2.91Å
101R86.8Confident78.5Confident101 Ų10165 Ų6538%0.38136%0.363SS..  trans-62.7109.5-176.3174.5171.9169.4166.4-8.5110.8C99 E107 D126 F148 C149C99-R101 PolarHBondContact O-N 3.05Å; R101-E107 IonicContact CZ-OE1 3.98Å; R101-E107 IonicContact NE-OE1 3.5Å; R101-E107 PolarHBondContact NE-OE1 3.17Å; R101-E107 IonicContact NH2-OE1 2.83Å; R101-E107 PolarHBondContact NH2-OE1 3.49Å; R101-D126 IonicContact CZ-OD2 3.58Å; R101-D126 IonicContact NH1-OD2 2.81Å; R101-D126 PolarHBondContact NH1-OD2 2.8Å; R101-F148 CarbonylContact O-C 3.52Å; R101-F148 WeakPolarHBondContact O-CA 3.33Å; R101-F148 WeakPolarHBondContact O-CB 3.27Å; R101-C149 HydrophobicContact CB-CB 4.23Å; R101-C149 PolarHBondContact O-N 3.18Å
102V84.3Confident79.7Confident60 Ų6058.6 Ų58.636%0.36434%0.336SS..BIsolated β-bridgetrans-67.6131.8173.7-175.70000110G100 G147 F148 F375G100-V102 PolarHBondContact O-N 2.91Å; V102-G147 CarbonylContact C-O 3.56Å; V102-G147 WeakPolarHBondContact CA-O 3.3Å; V102-F148 HydrophobicContact CG2-CB 4.35Å; V102-F375 HydrophobicContact CG1-CD2 4.32Å; V102-F375 HydrophobicContact CG2-CB 3.68Å; V102-F375 HydrophobicContact CG2-CD1 4.41Å; V102-F375 HydrophobicContact CG2-CD2 4.02Å; V102-F375 HydrophobicContact CG2-CG 3.79Å
103F86.4Confident81.1Confident9 Ų953.2 Ų53.24%0.03931%0.309CS..PPolyproline II helixtrans-84140-179.8-58.4-59.6000112.2E107 T109 V122 C124 S143 G147 F148 C149F103-E107 WeakPolarHBondContact CA-OE2 3.12Å; F103-T109 HydrophobicContact CD1-CG2 3.69Å; F103-T109 HydrophobicContact CD2-CG2 3.79Å; F103-T109 HydrophobicContact CE1-CG2 3.7Å; F103-T109 HydrophobicContact CE2-CG2 3.8Å; F103-T109 HydrophobicContact CG-CG2 3.74Å; F103-T109 HydrophobicContact CZ-CG2 3.75Å; F103-V122 HydrophobicContact CE2-CB 4.24Å; F103-V122 HydrophobicContact CE2-CG2 3.59Å; F103-V122 HydrophobicContact CZ-CB 4.49Å; F103-V122 HydrophobicContact CZ-CG2 4.23Å; F103-C124 HydrophobicContact CE1-CB 3.75Å; F103-C124 HydrophobicContact CZ-CB 4.46Å; F103-S143 WeakPolarHBondContact CB-OG 3.35Å; F103-G147 WeakPolarHBondContact CD2-O 3.44Å; F103-G147 PolarHBondContact N-O 3.12Å; F103-F148 VanDerWaalsContact CE2-O 3.24Å; F103-F148 WeakPolarHBondContact CE2-O 3.33Å; F103-C149 HydrophobicContact CE1-CB 4.4Å; F103-C149 HydrophobicContact CZ-CB 3.95Å
104K84.1Confident82.7Confident166 Ų16654.1 Ų54.172%0.72231%0.31SS*.PPolyproline II helixtrans-84.2154.2169.5-64.2177.6-177175.80110.6G106 E107 S143K104-G106 PolarHBondContact O-N 2.99Å; K104-E107 PolarHBondContact N-OE2 2.98Å; K104-E107 WeakPolarHBondContact O-CB 3.48Å; K104-E107 PolarHBondContact O-N 3.23Å; K104-E107 VanDerWaalsContact O-N 3.09Å; K104-S143 WeakPolarHBondContact O-CB 3.3Å
105S80.5Confident84.5Confident94 Ų9451.7 Ų51.766%0.65728%0.284SS*.THydrogen-bonded Turntrans-60.2136.1169.2-170.20000109.8E107 S143S105-E107 VanDerWaalsContact C-N 3.34Å; S105-S143 WeakPolarHBondContact CA-O 3.34Å
106G84.8Confident86.3Confident50 Ų5048.8 Ų48.852%0.51526%0.261SS..THydrogen-bonded Turntrans84.8-9.4-171.900000115.6K104 S143K104-G106 PolarHBondContact O-N 2.99Å; G106-S143 PolarHBondContact N-O 3.36Å
107E89.8Confident87.4Confident38 Ų3846.9 Ų46.918%0.17825%0.254CS..  trans-75.2140-179.4-169.2170.2-172.900112.1R101 F103 K104 S105 S143R101-E107 IonicContact CZ-OE1 3.98Å; R101-E107 IonicContact NE-OE1 3.5Å; R101-E107 PolarHBondContact NE-OE1 3.17Å; R101-E107 IonicContact NH2-OE1 2.83Å; R101-E107 PolarHBondContact NH2-OE1 3.49Å; F103-E107 WeakPolarHBondContact CA-OE2 3.12Å; K104-E107 PolarHBondContact N-OE2 2.98Å; K104-E107 WeakPolarHBondContact O-CB 3.48Å; K104-E107 PolarHBondContact O-N 3.23Å; K104-E107 VanDerWaalsContact O-N 3.09Å; S105-E107 VanDerWaalsContact C-N 3.34Å; E107-S143 VanDerWaalsContact O-CB 3.23Å; E107-S143 WeakPolarHBondContact O-CB 3.45Å; E107-S143 PolarHBondContact O-N 2.92Å
108T93.6Very high88.1Confident53 Ų5341 Ų4133%0.32523%0.227SC..EExtended strand (participates in β ladder)trans-80.6126.6-179.8-52.60000111.8Y110 M140 H141T108-Y110 HydrophobicContact CG2-CE2 4.02Å; T108-M140 HydrophobicContact CG2-CB 4.46Å; T108-M140 HydrophobicContact CG2-CE 3.64Å; T108-H141 WeakPolarHBondContact CA-O 3.2Å
109T94.6Very high88.2Confident7 Ų740.7 Ų40.74%0.04323%0.227CC..EExtended strand (participates in β ladder)trans-117.2156.1176.964.80000112F103 M140 H141F103-T109 HydrophobicContact CD1-CG2 3.69Å; F103-T109 HydrophobicContact CD2-CG2 3.79Å; F103-T109 HydrophobicContact CE1-CG2 3.7Å; F103-T109 HydrophobicContact CE2-CG2 3.8Å; F103-T109 HydrophobicContact CG-CG2 3.74Å; F103-T109 HydrophobicContact CZ-CG2 3.75Å; T109-M140 WeakPolarHBondContact O-CA 3.39Å; T109-H141 PolarHBondContact N-O 3.4Å; T109-H141 PolarHBondContact O-N 2.88Å
110Y94.8Very high88.2Confident13 Ų1341.3 Ų41.35%0.05123%0.23CC..EExtended strand (participates in β ladder)trans-125121.2-172.3-64.9-95.6000111.3T108 V122 L123 M125 F128 Y138 M140T108-Y110 HydrophobicContact CG2-CE2 4.02Å; Y110-V122 WeakPolarHBondContact O-CA 3.42Å; Y110-L123 PolarHBondContact N-O 3.32Å; Y110-L123 PolarHBondContact O-N 3.23Å; Y110-M125 HydrophobicContact CE2-CB 4.3Å; Y110-M125 HydrophobicContact CE2-CE 4.07Å; Y110-M125 HydrophobicContact CE2-SD 3.89Å; Y110-M125 WeakPolarHBondContact OH-CE 3.46Å; Y110-M125 PolarHBondContact OH-SD 3.35Å; Y110-M125 VanDerWaalsContact OH-SD 3.35Å; Y110-F128 AromaticContact CD1-CD1 3.47Å; Y110-F128 HydrophobicContact CD1-CD1 3.47Å; Y110-F128 VanDerWaalsContact CD1-CD1 3.47Å; Y110-F128 HydrophobicContact CD1-CD2 4.05Å; Y110-F128 AromaticContact CD1-CE1 3.52Å; Y110-F128 HydrophobicContact CD1-CE1 3.52Å; Y110-F128 HydrophobicContact CD1-CE2 4.09Å; Y110-F128 AromaticContact CD1-CG 3.74Å; Y110-F128 HydrophobicContact CD1-CG 3.74Å; Y110-F128 AromaticContact CD1-CZ 3.83Å; Y110-F128 HydrophobicContact CD1-CZ 3.83Å; Y110-F128 HydrophobicContact CD2-CB 4.04Å; Y110-F128 HydrophobicContact CD2-CD1 4.23Å; Y110-F128 HydrophobicContact CD2-CG 4.15Å; Y110-F128 AromaticContact CE1-CD1 3.74Å; Y110-F128 HydrophobicContact CE1-CD1 3.74Å; Y110-F128 AromaticContact CE1-CE1 3.71Å; Y110-F128 HydrophobicContact CE1-CE1 3.71Å; Y110-F128 HydrophobicContact CE1-CG 4.42Å; Y110-F128 HydrophobicContact CE1-CZ 4.38Å; Y110-F128 HydrophobicContact CE2-CD1 4.48Å; Y110-F128 HydrophobicContact CG-CB 3.91Å; Y110-F128 AromaticContact CG-CD1 3.75Å; Y110-F128 HydrophobicContact CG-CD1 3.75Å; Y110-F128 AromaticContact CG-CD2 3.97Å; Y110-F128 HydrophobicContact CG-CD2 3.97Å; Y110-F128 HydrophobicContact CG-CE1 4.25Å; Y110-F128 HydrophobicContact CG-CE2 4.44Å; Y110-F128 AromaticContact CG-CG 3.59Å; Y110-F128 HydrophobicContact CG-CG 3.59Å; Y110-Y138 AromaticContact CD1-CD2 3.97Å; Y110-Y138 HydrophobicContact CD1-CD2 3.97Å; Y110-Y138 HydrophobicContact CD1-CE2 4.02Å; Y110-Y138 HydrophobicContact CE1-CE2 4.18Å; Y110-M140 HydrophobicContact CD1-CG 3.79Å; Y110-M140 HydrophobicContact CE1-CE 4.09Å; Y110-M140 HydrophobicContact CE1-CG 3.53Å; Y110-M140 HydrophobicContact CE1-SD 3.89Å
111S93.3Very high88.8Confident2 Ų240.8 Ų40.81%0.01422%0.224CC..EExtended strand (participates in β ladder)trans-113.4122.1175.4-174.30000110.9C121 Y138 K139S111-C121 VanDerWaalsContact CB-O 3.22Å; S111-C121 WeakPolarHBondContact CB-O 3.24Å; S111-C121 PolarHBondContact OG-O 2.86Å; S111-Y138 CarbonylContact O-C 3.57Å; S111-Y138 WeakPolarHBondContact O-CA 3.46Å; S111-Y138 WeakPolarHBondContact O-CB 3.25Å; S111-K139 PolarHBondContact N-O 3.3Å; S111-K139 PolarHBondContact O-N 2.96Å
112C92.6Very high89.1Confident1 Ų137.2 Ų37.21%0.00721%0.213CC..EExtended strand (participates in β ladder)trans-85116179.7-1760000110.9D114 C115 A116 H133 H136 W157C112-D114 VanDerWaalsContact C-N 3.33Å; C112-D114 PolarHBondContact O-N 3.3Å; C112-C115 HydrophobicContact CB-CB 4.27Å; C112-A116 WeakPolarHBondContact O-CB 2.86Å; C112-A116 PolarHBondContact O-N 3.42Å; C112-H133 HydrophobicContact CB-CB 3.89Å; C112-H136 VanDerWaalsContact SG-CB 3.51Å; C112-W157 HydrophobicContact CB-CZ3 3.84Å
113R87.9Confident89.6Confident49 Ų4934.5 Ų34.519%0.18520%0.197CC..THydrogen-bonded Turntrans-70.8-28-176.4-58.5-48.2-148137.722.8113.6R137 N795R113-R137 HydrophobicContact CB-CB 4.34Å; R113-R137 PolarHBondContact N-O 3.32Å; R113-N795 PolarHBondContact NH1-O 3.03Å
114D88.2Confident90Very high66 Ų6634.1 Ų34.135%0.35320%0.195SC..THydrogen-bonded Turntrans-83.2-30.1-178.5-56.2-36.2000112.4C112 H136 R137C112-D114 VanDerWaalsContact C-N 3.33Å; C112-D114 PolarHBondContact O-N 3.3Å; D114-H136 HydrophobicContact CB-CB 4.32Å; D114-H136 WeakPolarHBondContact OD2-CB 3.21Å; D114-R137 IonicContact OD1-CZ 3.08Å; D114-R137 IonicContact OD1-NE 3.82Å; D114-R137 PolarHBondContact OD1-NE 3.2Å; D114-R137 IonicContact OD1-NH2 3.25Å; D114-R137 PolarHBondContact OD1-NH2 2.75Å; D114-R137 WeakPolarHBondContact OD2-CB 3.38Å; D114-R137 PolarHBondContact OD2-N 2.75Å; D114-R137 IonicContact OD2-NE 3.02Å
115C92.2Very high90.5Very high2 Ų229.7 Ų29.71%0.01418%0.178CC..THydrogen-bonded Turntrans-109.7-29.5-173-66.70000115.5C112 H133 H136 W157 K158 T159C112-C115 HydrophobicContact CB-CB 4.27Å; C115-H133 VanDerWaalsContact CB-CE1 3.43Å; C115-H133 WeakPolarHBondContact CB-CE1 3.48Å; C115-H133 WeakPolarHBondContact CB-ND1 3.41Å; C115-H136 PolarHBondContact SG-CE1 3.25Å; C115-H136 PolarHBondContact SG-ND1 2.78Å; C115-W157 HydrophobicContact CB-CE3 4.09Å; C115-K158 WeakPolarHBondContact O-CB 3.44Å; C115-K158 WeakPolarHBondContact O-CG 3.46Å; C115-K158 PolarHBondContact O-N 3.22Å; C115-T159 PolarHBondContact SG-OG1 3.05Å
116A90.8Very high91.2Very high6 Ų628.9 Ų28.95%0.0517%0.166CC..BIsolated β-bridgetrans-60145.2-178.800000110.9C112 D118 C121 W157 K158C112-A116 WeakPolarHBondContact O-CB 2.86Å; C112-A116 PolarHBondContact O-N 3.42Å; A116-D118 WeakPolarHBondContact CB-O 3.44Å; A116-C121 HydrophobicContact CB-CB 3.81Å; A116-W157 HydrophobicContact CB-CE3 4.19Å; A116-W157 HydrophobicContact CB-CZ3 3.8Å; A116-K158 VanDerWaalsContact O-CE 3.26Å; A116-K158 WeakPolarHBondContact O-CE 3.39Å; A116-K158 PolarHBondContact O-NZ 3.25Å
117I87.4Confident91.6Very high55 Ų5526.6 Ų26.628%0.28214%0.143SC..SBendtrans-67.1-45170.8-75.2-75.3000109.8E155 A156 K158 P425I117-E155 WeakPolarHBondContact CG1-O 3.48Å; I117-A156 PolarHBondContact N-O 3.37Å; I117-K158 HydrophobicContact CD1-CG 3.52Å; I117-K158 HydrophobicContact CG1-CG 4.15Å; I117-P425 HydrophobicContact CG2-CG 4.46Å
118D87.3Confident91.9Very high9 Ų925 Ų255%0.04814%0.135CC..SBendtrans-146.2175.5179.382.784.3000112.4A116 T120 C121 I484A116-D118 WeakPolarHBondContact CB-O 3.44Å; D118-T120 VanDerWaalsContact C-N 3.27Å; D118-T120 PolarHBondContact O-N 2.91Å; D118-T120 WeakPolarHBondContact OD1-CB 3.47Å; D118-T120 PolarHBondContact OD1-N 3.48Å; D118-T120 PolarHBondContact OD1-OG1 3.17Å; D118-C121 PolarHBondContact O-N 3.39Å; D118-C121 PolarHBondContact O-SG 2.95Å; D118-C121 VanDerWaalsContact O-SG 3.35Å; D118-I484 HydrophobicContact CB-CD1 4.25Å; D118-I484 HydrophobicContact CB-CG2 3.5Å
119P84.8Confident92Very high31 Ų3126.6 Ų26.620%0.20114%0.139CC..THydrogen-bonded Turntrans-69.5-10.8-175.5-21.436000116.6N795P119-N795 WeakPolarHBondContact CD-OD1 3.38Å; P119-N795 HydrophobicContact CG-CB 4.24Å
120T88.8Confident92Very high41 Ų4129.2 Ų29.225%0.25215%0.152SC..THydrogen-bonded Turntrans-80.1-18.517765.80000112.8D118 V122 V419 T423 Y481D118-T120 VanDerWaalsContact C-N 3.27Å; D118-T120 PolarHBondContact O-N 2.91Å; D118-T120 WeakPolarHBondContact OD1-CB 3.47Å; D118-T120 PolarHBondContact OD1-N 3.48Å; D118-T120 PolarHBondContact OD1-OG1 3.17Å; T120-V122 PolarHBondContact O-N 3.16Å; T120-V419 HydrophobicContact CG2-CG2 3.73Å; T120-T423 HydrophobicContact CG2-CG2 4.26Å; T120-T423 WeakPolarHBondContact OG1-CG2 3.33Å; T120-Y481 HydrophobicContact CG2-CD1 4.37Å; T120-Y481 HydrophobicContact CG2-CE1 3.88Å
121C91.7Very high92Very high4 Ų429 Ų293%0.02715%0.153CC..  trans-67124.1-179.1-44.80000111.6S111 A116 D118 D150 A156 W157S111-C121 VanDerWaalsContact CB-O 3.22Å; S111-C121 WeakPolarHBondContact CB-O 3.24Å; S111-C121 PolarHBondContact OG-O 2.86Å; A116-C121 HydrophobicContact CB-CB 3.81Å; D118-C121 PolarHBondContact O-N 3.39Å; D118-C121 PolarHBondContact O-SG 2.95Å; D118-C121 VanDerWaalsContact O-SG 3.35Å; C121-D150 VanDerWaalsContact CA-OD2 3.26Å; C121-D150 WeakPolarHBondContact CA-OD2 3.18Å; C121-A156 HydrophobicContact CB-CB 4.43Å; C121-A156 PolarHBondContact SG-O 2.59Å; C121-W157 HydrophobicContact CB-CH2 3.98Å; C121-W157 HydrophobicContact CB-CZ2 4.17Å; C121-W157 HydrophobicContact CB-CZ3 4.28Å
122V93.7Very high92Very high25 Ų2532.4 Ų32.415%0.15217%0.173CC..  trans-140.9142.3-170.3-770000113.5F103 Y110 T120 D150F103-V122 HydrophobicContact CE2-CB 4.24Å; F103-V122 HydrophobicContact CE2-CG2 3.59Å; F103-V122 HydrophobicContact CZ-CB 4.49Å; F103-V122 HydrophobicContact CZ-CG2 4.23Å; Y110-V122 WeakPolarHBondContact O-CA 3.42Å; T120-V122 PolarHBondContact O-N 3.16Å; V122-D150 PolarHBondContact N-OD2 3.31Å; V122-D150 PolarHBondContact O-N 3.17Å
123L95.1Very high92.1Very high3 Ų332.4 Ų32.42%0.01617%0.173CC..BIsolated β-bridgetrans-112.6145.3174.5-61.6169.6000110.6Y110 C127 F128 H133 C151 W157Y110-L123 PolarHBondContact N-O 3.32Å; Y110-L123 PolarHBondContact O-N 3.23Å; L123-C127 HydrophobicContact CD2-CB 4.25Å; L123-F128 HydrophobicContact CB-CB 4.11Å; L123-F128 HydrophobicContact CD1-CB 4.45Å; L123-F128 HydrophobicContact CD1-CD2 4.42Å; L123-H133 HydrophobicContact CD1-CB 4.3Å; L123-H133 VanDerWaalsContact CD1-CD2 3.47Å; L123-H133 WeakPolarHBondContact CD1-CD2 3.49Å; L123-C151 HydrophobicContact CD2-CB 3.73Å; L123-W157 HydrophobicContact CD1-CH2 4.03Å; L123-W157 HydrophobicContact CD1-CZ2 4.07Å; L123-W157 HydrophobicContact CD2-CH2 4.32Å; L123-W157 HydrophobicContact CD2-CZ2 3.57Å; L123-W157 HydrophobicContact CG-CH2 3.81Å; L123-W157 HydrophobicContact CG-CZ2 3.57Å
124C94.7Very high92.3Very high1 Ų134.4 Ų34.41%0.00718%0.183CC..  trans-68.5162162.373.30000110.8F103 D126 C127 F128 C149F103-C124 HydrophobicContact CE1-CB 3.75Å; F103-C124 HydrophobicContact CZ-CB 4.46Å; C124-D126 VanDerWaalsContact C-N 3.29Å; C124-D126 PolarHBondContact O-N 2.88Å; C124-C127 PolarHBondContact O-N 2.88Å; C124-C127 PolarHBondContact SG-N 3.34Å; C124-C127 VanDerWaalsContact SG-N 3.39Å; C124-F128 WeakPolarHBondContact O-CB 3.48Å; C124-F128 PolarHBondContact O-N 2.96Å; C124-C149 HydrophobicContact CB-CB 4.2Å; C124-C149 PolarHBondContact N-SG 2.95Å
125M94.2Very high92.6Very high73 Ų7337.5 Ų37.536%0.3620%0.2SC..Hα-helixtrans-46.8-52.2176.5-179.971.475.800112.2Y110 F128 Q129Y110-M125 HydrophobicContact CE2-CB 4.3Å; Y110-M125 HydrophobicContact CE2-CE 4.07Å; Y110-M125 HydrophobicContact CE2-SD 3.89Å; Y110-M125 WeakPolarHBondContact OH-CE 3.46Å; Y110-M125 PolarHBondContact OH-SD 3.35Å; Y110-M125 VanDerWaalsContact OH-SD 3.35Å; M125-F128 PolarHBondContact O-N 3.39Å; M125-Q129 HydrophobicContact CG-CG 4.49Å; M125-Q129 WeakPolarHBondContact O-CG 3.24Å; M125-Q129 PolarHBondContact O-N 3.31Å; M125-Q129 HydrophobicContact SD-CG 4.25Å
126D94.2Very high92.6Very high77 Ų7740.5 Ų40.541%0.41221%0.214SC..Hα-helixtrans-64.9-47.5-172.4-45.2-45.2000111R101 C124 F128 Q129 D130R101-D126 IonicContact CZ-OD2 3.58Å; R101-D126 IonicContact NH1-OD2 2.81Å; R101-D126 PolarHBondContact NH1-OD2 2.8Å; C124-D126 VanDerWaalsContact C-N 3.29Å; C124-D126 PolarHBondContact O-N 2.88Å; D126-F128 VanDerWaalsContact C-N 3.34Å; D126-F128 PolarHBondContact O-N 3.06Å; D126-Q129 PolarHBondContact O-N 2.73Å; D126-D130 WeakPolarHBondContact O-CB 3.44Å; D126-D130 PolarHBondContact O-N 3.2Å
127C94.9Very high92.5Very high3 Ų345 Ų452%0.0223%0.229CC..Hα-helixtrans-65.5-36.3176.8-70.30000112.6L123 C124 S131 C151 C163 H166L123-C127 HydrophobicContact CD2-CB 4.25Å; C124-C127 PolarHBondContact O-N 2.88Å; C124-C127 PolarHBondContact SG-N 3.34Å; C124-C127 VanDerWaalsContact SG-N 3.39Å; C127-S131 WeakPolarHBondContact O-CB 3.43Å; C127-S131 PolarHBondContact O-N 3.43Å; C127-S131 VanDerWaalsContact O-N 3.12Å; C127-S131 PolarHBondContact O-OG 3.32Å; C127-C151 HydrophobicContact CB-CB 3.75Å; C127-C151 VanDerWaalsContact SG-CB 3.56Å; C127-C151 VanDerWaalsContact SG-SG 3.63Å; C127-C163 HydrophobicContact CB-CB 4.27Å; C127-C163 WeakPolarHBondContact O-CB 3.34Å; C127-H166 PolarHBondContact SG-CE1 2.86Å
128F95.9Very high92.7Very high4 Ų447.5 Ų47.52%0.01824%0.236CC..Hα-helixtrans-63.4-49.9175.3174.8-106000111.3Y110 L123 C124 M125 D126 D130 S131 H133 K134 Y138Y110-F128 AromaticContact CD1-CD1 3.47Å; Y110-F128 HydrophobicContact CD1-CD1 3.47Å; Y110-F128 VanDerWaalsContact CD1-CD1 3.47Å; Y110-F128 HydrophobicContact CD1-CD2 4.05Å; Y110-F128 AromaticContact CD1-CE1 3.52Å; Y110-F128 HydrophobicContact CD1-CE1 3.52Å; Y110-F128 HydrophobicContact CD1-CE2 4.09Å; Y110-F128 AromaticContact CD1-CG 3.74Å; Y110-F128 HydrophobicContact CD1-CG 3.74Å; Y110-F128 AromaticContact CD1-CZ 3.83Å; Y110-F128 HydrophobicContact CD1-CZ 3.83Å; Y110-F128 HydrophobicContact CD2-CB 4.04Å; Y110-F128 HydrophobicContact CD2-CD1 4.23Å; Y110-F128 HydrophobicContact CD2-CG 4.15Å; Y110-F128 AromaticContact CE1-CD1 3.74Å; Y110-F128 HydrophobicContact CE1-CD1 3.74Å; Y110-F128 AromaticContact CE1-CE1 3.71Å; Y110-F128 HydrophobicContact CE1-CE1 3.71Å; Y110-F128 HydrophobicContact CE1-CG 4.42Å; Y110-F128 HydrophobicContact CE1-CZ 4.38Å; Y110-F128 HydrophobicContact CE2-CD1 4.48Å; Y110-F128 HydrophobicContact CG-CB 3.91Å; Y110-F128 AromaticContact CG-CD1 3.75Å; Y110-F128 HydrophobicContact CG-CD1 3.75Å; Y110-F128 AromaticContact CG-CD2 3.97Å; Y110-F128 HydrophobicContact CG-CD2 3.97Å; Y110-F128 HydrophobicContact CG-CE1 4.25Å; Y110-F128 HydrophobicContact CG-CE2 4.44Å; Y110-F128 AromaticContact CG-CG 3.59Å; Y110-F128 HydrophobicContact CG-CG 3.59Å; L123-F128 HydrophobicContact CB-CB 4.11Å; L123-F128 HydrophobicContact CD1-CB 4.45Å; L123-F128 HydrophobicContact CD1-CD2 4.42Å; C124-F128 WeakPolarHBondContact O-CB 3.48Å; C124-F128 PolarHBondContact O-N 2.96Å; M125-F128 PolarHBondContact O-N 3.39Å; D126-F128 VanDerWaalsContact C-N 3.34Å; D126-F128 PolarHBondContact O-N 3.06Å; F128-D130 VanDerWaalsContact C-N 3.29Å; F128-D130 PolarHBondContact O-N 3.23Å; F128-S131 PolarHBondContact O-N 2.77Å; F128-S131 PolarHBondContact O-OG 3.04Å; F128-H133 HydrophobicContact CD2-CB 4.31Å; F128-H133 HydrophobicContact CE2-CB 4.35Å; F128-K134 HydrophobicContact CE1-CB 4.1Å; F128-K134 HydrophobicContact CE2-CB 4.3Å; F128-K134 HydrophobicContact CZ-CB 3.93Å; F128-Y138 HydrophobicContact CE1-CE2 4.32Å; F128-Y138 HydrophobicContact CE2-CD1 4.02Å; F128-Y138 HydrophobicContact CE2-CD2 4.19Å; F128-Y138 AromaticContact CE2-CG 3.86Å; F128-Y138 HydrophobicContact CE2-CG 3.86Å; F128-Y138 AromaticContact CZ-CD1 3.61Å; F128-Y138 HydrophobicContact CZ-CD1 3.61Å; F128-Y138 AromaticContact CZ-CD2 3.81Å; F128-Y138 HydrophobicContact CZ-CD2 3.81Å; F128-Y138 AromaticContact CZ-CE1 3.66Å; F128-Y138 HydrophobicContact CZ-CE1 3.66Å; F128-Y138 AromaticContact CZ-CE2 3.84Å; F128-Y138 HydrophobicContact CZ-CE2 3.84Å; F128-Y138 AromaticContact CZ-CG 3.7Å; F128-Y138 HydrophobicContact CZ-CG 3.7Å; F128-Y138 AromaticContact CZ-CZ 3.77Å
129Q95.3Very high92.8Very high87 Ų8751.6 Ų51.641%0.40725%0.253SS..Hα-helixtrans-63.2-33178.5-66.6-62.3-14.600112.9M125 D126 K134M125-Q129 HydrophobicContact CG-CG 4.49Å; M125-Q129 WeakPolarHBondContact O-CG 3.24Å; M125-Q129 PolarHBondContact O-N 3.31Å; M125-Q129 HydrophobicContact SD-CG 4.25Å; D126-Q129 PolarHBondContact O-N 2.73Å; Q129-K134 VanDerWaalsContact O-CD 3.28Å; Q129-K134 WeakPolarHBondContact O-CD 3.19Å; Q129-K134 VanDerWaalsContact O-CE 3.3Å; Q129-K134 WeakPolarHBondContact O-CE 3.33Å; Q129-K134 PolarHBondContact O-NZ 3.48Å
130D94.4Very high93.1Very high61 Ų6154.9 Ų54.933%0.32627%0.267SS..THydrogen-bonded Turntrans-94.211.9179.3-71-25.3000113.9D126 F128 C163 V164 N165D126-D130 WeakPolarHBondContact O-CB 3.44Å; D126-D130 PolarHBondContact O-N 3.2Å; F128-D130 VanDerWaalsContact C-N 3.29Å; F128-D130 PolarHBondContact O-N 3.23Å; D130-C163 HydrophobicContact CB-CB 4.13Å; D130-C163 WeakPolarHBondContact O-CA 3.36Å; D130-C163 WeakPolarHBondContact O-CB 2.93Å; D130-V164 HydrophobicContact CB-CB 4.32Å; D130-V164 WeakPolarHBondContact O-CG2 3.49Å; D130-V164 PolarHBondContact O-N 3.19Å; D130-N165 PolarHBondContact OD2-ND2 3.11Å
131S93.8Very high93.1Very high10 Ų1056.3 Ų56.37%0.0727%0.271CS..SBendtrans-110.3173.3177.871.60000113.3C127 F128 H133C127-S131 WeakPolarHBondContact O-CB 3.43Å; C127-S131 PolarHBondContact O-N 3.43Å; C127-S131 VanDerWaalsContact O-N 3.12Å; C127-S131 PolarHBondContact O-OG 3.32Å; F128-S131 PolarHBondContact O-N 2.77Å; F128-S131 PolarHBondContact O-OG 3.04Å; S131-H133 PolarHBondContact O-N 2.99Å; S131-H133 WeakPolarHBondContact OG-CB 3.5Å; S131-H133 PolarHBondContact OG-CD2 2.84Å; S131-H133 VanDerWaalsContact OG-CD2 3.32Å; S131-H133 PolarHBondContact OG-N 2.81Å
132V94Very high93.1Very high72 Ų7261 Ų6144%0.43630%0.3SS..G310 helixtrans-67.6-24.8168.9-63.60000112.7K134 N135V132-K134 VanDerWaalsContact C-N 3.26Å; V132-K134 PolarHBondContact O-N 3.13Å; V132-N135 PolarHBondContact O-N 3.42Å; V132-N135 VanDerWaalsContact O-N 3.16Å
133H94.3Very high92.7Very high1 Ų160.6 Ų60.61%0.00530%0.298CS..G310 helixtrans-66.9-20.9-168.5-56.3-62.5000114.6C112 C115 L123 F128 S131 N135 H136 W157 T159 G160C112-H133 HydrophobicContact CB-CB 3.89Å; C115-H133 VanDerWaalsContact CB-CE1 3.43Å; C115-H133 WeakPolarHBondContact CB-CE1 3.48Å; C115-H133 WeakPolarHBondContact CB-ND1 3.41Å; L123-H133 HydrophobicContact CD1-CB 4.3Å; L123-H133 VanDerWaalsContact CD1-CD2 3.47Å; L123-H133 WeakPolarHBondContact CD1-CD2 3.49Å; F128-H133 HydrophobicContact CD2-CB 4.31Å; F128-H133 HydrophobicContact CE2-CB 4.35Å; S131-H133 PolarHBondContact O-N 2.99Å; S131-H133 WeakPolarHBondContact OG-CB 3.5Å; S131-H133 PolarHBondContact OG-CD2 2.84Å; S131-H133 VanDerWaalsContact OG-CD2 3.32Å; S131-H133 PolarHBondContact OG-N 2.81Å; H133-N135 PolarHBondContact O-N 3.16Å; H133-H136 WeakPolarHBondContact O-CB 3.46Å; H133-H136 PolarHBondContact O-N 3.11Å; H133-W157 AromaticContact CE1-CE3 3.84Å; H133-T159 PolarHBondContact CE1-O 3.41Å; H133-G160 PolarHBondContact NE2-O 3.03Å
134K93.9Very high91.7Very high92 Ų9265.4 Ų65.440%0.433%0.327SS..G310 helixtrans-61.5-20.2174.269.3-177.5169.1-170.70114.3F128 Q129 V132F128-K134 HydrophobicContact CE1-CB 4.1Å; F128-K134 HydrophobicContact CE2-CB 4.3Å; F128-K134 HydrophobicContact CZ-CB 3.93Å; Q129-K134 VanDerWaalsContact O-CD 3.28Å; Q129-K134 WeakPolarHBondContact O-CD 3.19Å; Q129-K134 VanDerWaalsContact O-CE 3.3Å; Q129-K134 WeakPolarHBondContact O-CE 3.33Å; Q129-K134 PolarHBondContact O-NZ 3.48Å; V132-K134 VanDerWaalsContact C-N 3.26Å; V132-K134 PolarHBondContact O-N 3.13Å
135N93.8Very high90.6Very high131 Ų13166.2 Ų66.270%0.70134%0.336SS*.G310 helixtrans-96.12.3178.3-57.3-49.7000113V132 H133V132-N135 PolarHBondContact O-N 3.42Å; V132-N135 VanDerWaalsContact O-N 3.16Å; H133-N135 PolarHBondContact O-N 3.16Å
136H92.6Very high89.4Confident65 Ų6563.6 Ų63.630%0.30133%0.327SS..SBendtrans-105.8177.2-177.9-63175.1000110.8C112 D114 C115 H133 Y138C112-H136 VanDerWaalsContact SG-CB 3.51Å; D114-H136 HydrophobicContact CB-CB 4.32Å; D114-H136 WeakPolarHBondContact OD2-CB 3.21Å; C115-H136 PolarHBondContact SG-CE1 3.25Å; C115-H136 PolarHBondContact SG-ND1 2.78Å; H133-H136 WeakPolarHBondContact O-CB 3.46Å; H133-H136 PolarHBondContact O-N 3.11Å; H136-Y138 WeakPolarHBondContact O-CD1 3.44Å; H136-Y138 PolarHBondContact O-N 3.34Å
137R88.6Confident88.8Confident101 Ų10160.4 Ų60.438%0.38131%0.313SS..  trans-70.9126.9167.1-58.2-177.6-57136.716.4108.8R113 D114 E797R113-R137 HydrophobicContact CB-CB 4.34Å; R113-R137 PolarHBondContact N-O 3.32Å; D114-R137 IonicContact OD1-CZ 3.08Å; D114-R137 IonicContact OD1-NE 3.82Å; D114-R137 PolarHBondContact OD1-NE 3.2Å; D114-R137 IonicContact OD1-NH2 3.25Å; D114-R137 PolarHBondContact OD1-NH2 2.75Å; D114-R137 WeakPolarHBondContact OD2-CB 3.38Å; D114-R137 PolarHBondContact OD2-N 2.75Å; D114-R137 IonicContact OD2-NE 3.02Å; R137-E797 IonicContact CZ-OE1 2.83Å; R137-E797 IonicContact NH1-OE1 2.75Å; R137-E797 IonicContact NH2-OE1 3.32Å; R137-E797 PolarHBondContact NH2-OE1 3.46Å
138Y91.2Very high88.5Confident106 Ų10660.7 Ų60.742%0.41631%0.314SS..EExtended strand (participates in β ladder)trans-136.5163.7177.966.7-88.4000111.5Y110 S111 F128 H136 M140Y110-Y138 AromaticContact CD1-CD2 3.97Å; Y110-Y138 HydrophobicContact CD1-CD2 3.97Å; Y110-Y138 HydrophobicContact CD1-CE2 4.02Å; Y110-Y138 HydrophobicContact CE1-CE2 4.18Å; S111-Y138 CarbonylContact O-C 3.57Å; S111-Y138 WeakPolarHBondContact O-CA 3.46Å; S111-Y138 WeakPolarHBondContact O-CB 3.25Å; F128-Y138 HydrophobicContact CE1-CE2 4.32Å; F128-Y138 HydrophobicContact CE2-CD1 4.02Å; F128-Y138 HydrophobicContact CE2-CD2 4.19Å; F128-Y138 AromaticContact CE2-CG 3.86Å; F128-Y138 HydrophobicContact CE2-CG 3.86Å; F128-Y138 AromaticContact CZ-CD1 3.61Å; F128-Y138 HydrophobicContact CZ-CD1 3.61Å; F128-Y138 AromaticContact CZ-CD2 3.81Å; F128-Y138 HydrophobicContact CZ-CD2 3.81Å; F128-Y138 AromaticContact CZ-CE1 3.66Å; F128-Y138 HydrophobicContact CZ-CE1 3.66Å; F128-Y138 AromaticContact CZ-CE2 3.84Å; F128-Y138 HydrophobicContact CZ-CE2 3.84Å; F128-Y138 AromaticContact CZ-CG 3.7Å; F128-Y138 HydrophobicContact CZ-CG 3.7Å; F128-Y138 AromaticContact CZ-CZ 3.77Å; H136-Y138 WeakPolarHBondContact O-CD1 3.44Å; H136-Y138 PolarHBondContact O-N 3.34Å; Y138-M140 HydrophobicContact CD2-CG 4.19Å; Y138-M140 HydrophobicContact CE2-CG 3.89Å; Y138-M140 HydrophobicContact CE2-SD 4.14Å
139K89Confident88.3Confident96 Ų9660.5 Ų60.542%0.41731%0.313SS..EExtended strand (participates in β ladder)trans-124.4138170.6-172.5173.1168.2-177.60109.5S111 H141S111-K139 PolarHBondContact N-O 3.3Å; S111-K139 PolarHBondContact O-N 2.96Å; K139-H141 VanDerWaalsContact CD-NE2 3.28Å; K139-H141 WeakPolarHBondContact CD-NE2 3.4Å; K139-H141 WeakPolarHBondContact CE-NE2 3.47Å; K139-H141 WeakPolarHBondContact CG-NE2 3.37Å
140M92.3Very high88.2Confident99 Ų9957.1 Ų57.149%0.48830%0.298SS..EExtended strand (participates in β ladder)trans-92.2140.4172.3-67.4169.365.500109.7T108 T109 Y110 Y138T108-M140 HydrophobicContact CG2-CB 4.46Å; T108-M140 HydrophobicContact CG2-CE 3.64Å; T109-M140 WeakPolarHBondContact O-CA 3.39Å; Y110-M140 HydrophobicContact CD1-CG 3.79Å; Y110-M140 HydrophobicContact CE1-CE 4.09Å; Y110-M140 HydrophobicContact CE1-CG 3.53Å; Y110-M140 HydrophobicContact CE1-SD 3.89Å; Y138-M140 HydrophobicContact CD2-CG 4.19Å; Y138-M140 HydrophobicContact CE2-CG 3.89Å; Y138-M140 HydrophobicContact CE2-SD 4.14Å
141H88.6Confident88.1Confident72 Ų7254.3 Ų54.333%0.33328%0.283SS..EExtended strand (participates in β ladder)trans-132.3151.4177.4-71.1-106.4000109.6T108 T109 K139T108-H141 WeakPolarHBondContact CA-O 3.2Å; T109-H141 PolarHBondContact N-O 3.4Å; T109-H141 PolarHBondContact O-N 2.88Å; K139-H141 VanDerWaalsContact CD-NE2 3.28Å; K139-H141 WeakPolarHBondContact CD-NE2 3.4Å; K139-H141 WeakPolarHBondContact CE-NE2 3.47Å; K139-H141 WeakPolarHBondContact CG-NE2 3.37Å
142T91.1Very high87.8Confident103 Ų10354.2 Ų54.263%0.63228%0.284SS*.EExtended strand (participates in β ladder)trans-91.8123.6166.1-52.30000107.6
143S85Confident87.6Confident15 Ų1551.5 Ų51.511%0.10527%0.266CS..  trans-67.6138.9175.6-177.50000110.8F103 K104 S105 G106 E107 G145F103-S143 WeakPolarHBondContact CB-OG 3.35Å; K104-S143 WeakPolarHBondContact O-CB 3.3Å; S105-S143 WeakPolarHBondContact CA-O 3.34Å; G106-S143 PolarHBondContact N-O 3.36Å; E107-S143 VanDerWaalsContact O-CB 3.23Å; E107-S143 WeakPolarHBondContact O-CB 3.45Å; E107-S143 PolarHBondContact O-N 2.92Å; S143-G145 VanDerWaalsContact C-N 3.29Å; S143-G145 PolarHBondContact OG-N 3.44Å
144T75Confident87.3Confident105 Ų10555.9 Ų55.964%0.64429%0.294SS*.  trans-88.22.5167.549.50000112.5
145G71.4Confident87Confident17 Ų1753.4 Ų53.418%0.17528%0.284CS..SBendtrans83.9170.7-163.700000112.4S143S143-G145 VanDerWaalsContact C-N 3.29Å; S143-G145 PolarHBondContact OG-N 3.44Å
146G68.2Low86.8Confident18 Ų1847.6 Ų47.619%0.18625%0.254CS..SBendtrans86.114.7172.800000116.9
147G81.2Confident86.8Confident11 Ų1144.9 Ų44.911%0.11324%0.241CC..  trans-141.6172175.100000112.8V102 F103V102-G147 CarbonylContact C-O 3.56Å; V102-G147 WeakPolarHBondContact CA-O 3.3Å; F103-G147 WeakPolarHBondContact CD2-O 3.44Å; F103-G147 PolarHBondContact N-O 3.12Å
148F88.3Confident86.9Confident9 Ų945.4 Ų45.44%0.03925%0.246CC..BIsolated β-bridgetrans-135.7169.8179.867.4-86.2000113.1R101 V102 F103 F375 F379 Q420R101-F148 CarbonylContact O-C 3.52Å; R101-F148 WeakPolarHBondContact O-CA 3.33Å; R101-F148 WeakPolarHBondContact O-CB 3.27Å; V102-F148 HydrophobicContact CG2-CB 4.35Å; F103-F148 VanDerWaalsContact CE2-O 3.24Å; F103-F148 WeakPolarHBondContact CE2-O 3.33Å; F148-F375 AromaticContact CD1-CD1 3.47Å; F148-F375 HydrophobicContact CD1-CD1 3.47Å; F148-F375 VanDerWaalsContact CD1-CD1 3.47Å; F148-F375 AromaticContact CD1-CE1 3.43Å; F148-F375 HydrophobicContact CD1-CE1 3.43Å; F148-F375 VanDerWaalsContact CD1-CE1 3.43Å; F148-F375 AromaticContact CE1-CD1 3.97Å; F148-F375 HydrophobicContact CE1-CD1 3.97Å; F148-F375 AromaticContact CE1-CE1 3.9Å; F148-F375 HydrophobicContact CE1-CE1 3.9Å; F148-F375 HydrophobicContact CG-CD1 4.35Å; F148-F379 HydrophobicContact CE1-CB 4.41Å; F148-F379 AromaticContact CE1-CD2 3.99Å; F148-F379 HydrophobicContact CE1-CD2 3.99Å; F148-Q420 HydrophobicContact CE1-CB 4.43Å; F148-Q420 HydrophobicContact CE1-CG 4.21Å
149C92.5Very high86.9Confident0 Ų044.4 Ų44.40%025%0.251CS..  trans-74.4118.4-178.9-177.10000112.9C99 R101 F103 C124 C151C99-C149 HydrophobicContact CB-CB 4.14Å; R101-C149 HydrophobicContact CB-CB 4.23Å; R101-C149 PolarHBondContact O-N 3.18Å; F103-C149 HydrophobicContact CE1-CB 4.4Å; F103-C149 HydrophobicContact CZ-CB 3.95Å; C124-C149 HydrophobicContact CB-CB 4.2Å; C124-C149 PolarHBondContact N-SG 2.95Å; C149-C151 PolarHBondContact O-N 2.93Å; C149-C151 VanDerWaalsContact O-N 3.1Å; C149-C151 VanDerWaalsContact SG-CB 3.58Å
150D92.4Very high87Confident16 Ų1641.2 Ų41.29%0.08625%0.245CC..  trans-77.112.8-179.6-56.7-55.6000114.3C121 V122 G152 D153 A156 W157C121-D150 VanDerWaalsContact CA-OD2 3.26Å; C121-D150 WeakPolarHBondContact CA-OD2 3.18Å; V122-D150 PolarHBondContact N-OD2 3.31Å; V122-D150 PolarHBondContact O-N 3.17Å; D150-G152 PolarHBondContact O-N 2.94Å; D150-D153 PolarHBondContact O-N 2.81Å; D150-D153 VanDerWaalsContact O-N 3.12Å; D150-A156 HydrophobicContact CB-CB 3.83Å; D150-W157 HydrophobicContact CB-CZ2 4.15Å; D150-W157 PolarHBondContact O-NE1 3.13Å
151C92.7Very high87Confident1 Ų137.6 Ų37.61%0.00723%0.229CC..THydrogen-bonded Turntrans-66.7121.8176-175.20000109.5L98 C99 L123 C127 C149 C163L98-C151 WeakPolarHBondContact CA-O 3.41Å; C99-C151 HydrophobicContact CB-CB 3.75Å; C99-C151 PolarHBondContact N-O 2.96Å; L123-C151 HydrophobicContact CD2-CB 3.73Å; C127-C151 HydrophobicContact CB-CB 3.75Å; C127-C151 VanDerWaalsContact SG-CB 3.56Å; C127-C151 VanDerWaalsContact SG-SG 3.63Å; C149-C151 PolarHBondContact O-N 2.93Å; C149-C151 VanDerWaalsContact O-N 3.1Å; C149-C151 VanDerWaalsContact SG-CB 3.58Å; C151-C163 PolarHBondContact SG-N 3.43Å
152G88.5Confident87.2Confident9 Ų937 Ų379%0.09323%0.226CC..THydrogen-bonded Turntrans101.3-15.9-173.800000115Q97 L98 D150 T154 P161Q97-G152 VanDerWaalsContact O-CA 3.24Å; Q97-G152 WeakPolarHBondContact O-CA 3.41Å; L98-G152 VanDerWaalsContact CD2-C 3.41Å; D150-G152 PolarHBondContact O-N 2.94Å; G152-T154 PolarHBondContact O-N 2.9Å; G152-P161 PolarHBondContact N-O 2.74Å
153D88.2Confident87.2Confident14 Ų1432.2 Ų32.28%0.07520%0.196CC..  trans-80.4109.5178.9-165.2-40.4000110L98 D150 E155 A156 W157L98-D153 HydrophobicContact CD2-CB 4.06Å; D150-D153 PolarHBondContact O-N 2.81Å; D150-D153 VanDerWaalsContact O-N 3.12Å; D153-E155 PolarHBondContact O-N 2.95Å; D153-E155 WeakPolarHBondContact OD1-CA 3.49Å; D153-E155 WeakPolarHBondContact OD1-CB 2.92Å; D153-E155 PolarHBondContact OD1-N 2.99Å; D153-A156 HydrophobicContact CB-CB 4.01Å; D153-A156 PolarHBondContact O-N 3.07Å; D153-A156 PolarHBondContact OD1-N 3.12Å; D153-W157 VanDerWaalsContact O-CD1 3.29Å
154T88.6Confident87.4Confident94 Ų9434.3 Ų34.358%0.57721%0.208SC*.THydrogen-bonded Turntrans-71.7-11.6-17955.40000113.6G152 P161 F162G152-T154 PolarHBondContact O-N 2.9Å; T154-P161 HydrophobicContact CG2-CB 4.41Å; T154-P161 HydrophobicContact CG2-CG 4.09Å; T154-F162 HydrophobicContact CG2-CE2 4.23Å; T154-F162 HydrophobicContact CG2-CZ 3.94Å
155E88.6Confident87.8Confident40 Ų4033.7 Ų33.719%0.18720%0.201CC..THydrogen-bonded Turntrans-96.1-13.8174.8-58.4-164.9-141.500113.8I117 D153 P425 T426I117-E155 WeakPolarHBondContact CG1-O 3.48Å; D153-E155 PolarHBondContact O-N 2.95Å; D153-E155 WeakPolarHBondContact OD1-CA 3.49Å; D153-E155 WeakPolarHBondContact OD1-CB 2.92Å; D153-E155 PolarHBondContact OD1-N 2.99Å; E155-P425 HydrophobicContact CB-CG 4.23Å; E155-P425 WeakPolarHBondContact OE2-CD 3.28Å; E155-T426 VanDerWaalsContact CD-OG1 3.25Å; E155-T426 WeakPolarHBondContact OE1-CB 3.46Å; E155-T426 WeakPolarHBondContact OE1-CG2 3.25Å; E155-T426 PolarHBondContact OE1-OG1 2.91Å; E155-T426 WeakPolarHBondContact OE2-CB 3.35Å; E155-T426 VanDerWaalsContact OE2-CG2 3.26Å; E155-T426 WeakPolarHBondContact OE2-CG2 3.39Å; E155-T426 PolarHBondContact OE2-N 3.48Å; E155-T426 PolarHBondContact OE2-OG1 3.31Å; E155-T426 VanDerWaalsContact OE2-OG1 3.1Å
156A89.6Confident88.4Confident9 Ų934.7 Ų34.77%0.07420%0.201CC..THydrogen-bonded Turntrans-80.7-23.617400000113.3I117 C121 D150 D153I117-A156 PolarHBondContact N-O 3.37Å; C121-A156 HydrophobicContact CB-CB 4.43Å; C121-A156 PolarHBondContact SG-O 2.59Å; D150-A156 HydrophobicContact CB-CB 3.83Å; D153-A156 HydrophobicContact CB-CB 4.01Å; D153-A156 PolarHBondContact O-N 3.07Å; D153-A156 PolarHBondContact OD1-N 3.12Å
157W91.4Very high89.1Confident8 Ų838.1 Ų38.13%0.0321%0.212CC..BIsolated β-bridgetrans-125.6127.3-171.7-50.997.6000112.9C112 C115 A116 C121 L123 H133 D150 D153 T159 P161C112-W157 HydrophobicContact CB-CZ3 3.84Å; C115-W157 HydrophobicContact CB-CE3 4.09Å; A116-W157 HydrophobicContact CB-CE3 4.19Å; A116-W157 HydrophobicContact CB-CZ3 3.8Å; C121-W157 HydrophobicContact CB-CH2 3.98Å; C121-W157 HydrophobicContact CB-CZ2 4.17Å; C121-W157 HydrophobicContact CB-CZ3 4.28Å; L123-W157 HydrophobicContact CD1-CH2 4.03Å; L123-W157 HydrophobicContact CD1-CZ2 4.07Å; L123-W157 HydrophobicContact CD2-CH2 4.32Å; L123-W157 HydrophobicContact CD2-CZ2 3.57Å; L123-W157 HydrophobicContact CG-CH2 3.81Å; L123-W157 HydrophobicContact CG-CZ2 3.57Å; H133-W157 AromaticContact CE1-CE3 3.84Å; D150-W157 HydrophobicContact CB-CZ2 4.15Å; D150-W157 PolarHBondContact O-NE1 3.13Å; D153-W157 VanDerWaalsContact O-CD1 3.29Å; W157-T159 PolarHBondContact O-N 2.9Å; W157-P161 HydrophobicContact CB-CB 4.08Å; W157-P161 HydrophobicContact CG-CB 4.28Å
158K90.3Very high88.6Confident112 Ų11241 Ų4149%0.48723%0.229SC..SBendtrans-59.3-36.5171.5-64.1164.9179139.10112C115 A116 I117C115-K158 WeakPolarHBondContact O-CB 3.44Å; C115-K158 WeakPolarHBondContact O-CG 3.46Å; C115-K158 PolarHBondContact O-N 3.22Å; A116-K158 VanDerWaalsContact O-CE 3.26Å; A116-K158 WeakPolarHBondContact O-CE 3.39Å; A116-K158 PolarHBondContact O-NZ 3.25Å; I117-K158 HydrophobicContact CD1-CG 3.52Å; I117-K158 HydrophobicContact CG1-CG 4.15Å
159T91.4Very high87.3Confident84 Ų8443.9 Ų43.952%0.51526%0.262SS..SBendtrans-152.4146.3-179.8540000110.4C115 H133 W157C115-T159 PolarHBondContact SG-OG1 3.05Å; H133-T159 PolarHBondContact CE1-O 3.41Å; W157-T159 PolarHBondContact O-N 2.9Å
160G91.8Very high85.4Confident29 Ų2951.5 Ų51.530%0.29929%0.29SS..  trans71.339.9174.500000117.3H133 F162H133-G160 PolarHBondContact NE2-O 3.03Å; G160-F162 PolarHBondContact O-N 3Å
161P92.5Very high83.3Confident24 Ų2453.9 Ų53.916%0.15631%0.312CS..  trans-62.5-16.2-171.924.8-34.4000116G152 T154 W157G152-P161 PolarHBondContact N-O 2.74Å; T154-P161 HydrophobicContact CG2-CB 4.41Å; T154-P161 HydrophobicContact CG2-CG 4.09Å; W157-P161 HydrophobicContact CB-CB 4.08Å; W157-P161 HydrophobicContact CG-CB 4.28Å
162F92.3Very high80.7Confident59 Ų5956.6 Ų56.626%0.25934%0.341SS..  trans-108.4138.5-177.6-54.4-79.3000111.7T154 G160 H166 P168T154-F162 HydrophobicContact CG2-CE2 4.23Å; T154-F162 HydrophobicContact CG2-CZ 3.94Å; G160-F162 PolarHBondContact O-N 3Å; F162-H166 VanDerWaalsContact CD1-O 3.27Å; F162-H166 WeakPolarHBondContact CD1-O 3.35Å; F162-P168 HydrophobicContact CD1-CG 4.25Å; F162-P168 HydrophobicContact CD2-CG 4.45Å; F162-P168 HydrophobicContact CE1-CG 3.87Å; F162-P168 HydrophobicContact CE2-CG 4.08Å; F162-P168 HydrophobicContact CZ-CG 3.79Å
163C91.8Very high78.4Confident2 Ų263 Ų631%0.01438%0.378CS..  trans-83.3166.8159.183.20000110.6C127 D130 C151 N165 H166 E167C127-C163 HydrophobicContact CB-CB 4.27Å; C127-C163 WeakPolarHBondContact O-CB 3.34Å; D130-C163 HydrophobicContact CB-CB 4.13Å; D130-C163 WeakPolarHBondContact O-CA 3.36Å; D130-C163 WeakPolarHBondContact O-CB 2.93Å; C151-C163 PolarHBondContact SG-N 3.43Å; C163-N165 PolarHBondContact O-N 2.92Å; C163-H166 PolarHBondContact O-N 3.21Å; C163-H166 PolarHBondContact SG-ND1 3.33Å; C163-E167 PolarHBondContact O-N 3.37Å; C163-E167 VanDerWaalsContact O-N 3.11Å
164V88.1Confident76Confident59 Ų5968.9 Ų68.936%0.35841%0.408SS..THydrogen-bonded Turntrans-52.5-30.2-178.7165.50000113.8D130 R170D130-V164 HydrophobicContact CB-CB 4.32Å; D130-V164 WeakPolarHBondContact O-CG2 3.49Å; D130-V164 PolarHBondContact O-N 3.19Å; V164-R170 WeakPolarHBondContact O-CD 3.4Å
165N83.1Confident73.4Confident93 Ų9373.4 Ų73.450%0.49742%0.42SS..THydrogen-bonded Turntrans-86.5-19.3-177.1-55.5-31.8000113.7D130 C163D130-N165 PolarHBondContact OD2-ND2 3.11Å; C163-N165 PolarHBondContact O-N 2.92Å
166H85.3Confident71Confident38 Ų3881 Ų8118%0.17646%0.455CS..THydrogen-bonded Turntrans-111.69.1179.4-55.7103.9000112.2F96 C127 F162 C163 P168F96-H166 PolarHBondContact O-CD2 3.31Å; C127-H166 PolarHBondContact SG-CE1 2.86Å; F162-H166 VanDerWaalsContact CD1-O 3.27Å; F162-H166 WeakPolarHBondContact CD1-O 3.35Å; C163-H166 PolarHBondContact O-N 3.21Å; C163-H166 PolarHBondContact SG-ND1 3.33Å; H166-P168 WeakPolarHBondContact O-CD 3.19Å
167E82.4Confident68.5Low90 Ų9088.2 Ų88.242%0.42149%0.492SS..  trans-67122.2-179.8-172.9171.2-138.400111.5C163 G169 R170C163-E167 PolarHBondContact O-N 3.37Å; C163-E167 VanDerWaalsContact O-N 3.11Å; E167-G169 PolarHBondContact O-N 3.49Å; E167-R170 PolarHBondContact O-N 3.07Å; E167-R170 IonicContact OE2-CZ 2.73Å; E167-R170 IonicContact OE2-NE 3.95Å; E167-R170 PolarHBondContact OE2-NE 3.41Å; E167-R170 IonicContact OE2-NH2 2.84Å; E167-R170 PolarHBondContact OE2-NH2 2.99Å
168P71.8Confident66Low70 Ų7091.5 Ų91.546%0.45552%0.517SS..THydrogen-bonded Turntrans-58123.5-179.5-26.234.9000112.5F162 H166F162-P168 HydrophobicContact CD1-CG 4.25Å; F162-P168 HydrophobicContact CD2-CG 4.45Å; F162-P168 HydrophobicContact CE1-CG 3.87Å; F162-P168 HydrophobicContact CE2-CG 4.08Å; F162-P168 HydrophobicContact CZ-CG 3.79Å; H166-P168 WeakPolarHBondContact O-CD 3.19Å
169G59.6Low63.9Low71 Ų7194.2 Ų94.273%0.73252%0.524SS*.THydrogen-bonded Turntrans961.7173.700000116.7E167E167-G169 PolarHBondContact O-N 3.49Å
170R53.1Low61.8Low160 Ų16094 Ų9460%0.60453%0.525SS*.  trans-73.9-26.9170.1-86.8-170.2-177.3-1303.3114.5V164 E167 G172V164-R170 WeakPolarHBondContact O-CD 3.4Å; E167-R170 PolarHBondContact O-N 3.07Å; E167-R170 IonicContact OE2-CZ 2.73Å; E167-R170 IonicContact OE2-NE 3.95Å; E167-R170 PolarHBondContact OE2-NE 3.41Å; E167-R170 IonicContact OE2-NH2 2.84Å; E167-R170 PolarHBondContact OE2-NH2 2.99Å; R170-G172 PolarHBondContact O-N 2.55Å
171A48.8Very low60.2Low65 Ų6596.7 Ų96.754%0.53754%0.537SS..SBendtrans-66.6112.9165.400000108.3A95 T173A95-A171 HydrophobicContact CB-CB 4.42Å; A171-T173 PolarHBondContact O-N 2.84Å
172G38.6Very low59.2Low59 Ų5996 Ų9661%0.60853%0.532SS*.  trans-58.7123.2-16100000115.3R170R170-G172 PolarHBondContact O-N 2.55Å
173T38.8Very low58.7Low144 Ų14497.7 Ų97.788%0.88354%0.544SS*.SBendtrans53.765.515551.90000117.6A171A171-T173 PolarHBondContact O-N 2.84Å
174I37.5Very low58.3Low137 Ų137103.6 Ų103.670%0.70357%0.571SS**  trans-132.3144.6146.2-43.9179.4000109.6S178I174-S178 VanDerWaalsContact CG2-CB 3.46Å; I174-S178 WeakPolarHBondContact CG2-OG 3.11Å
175K34.5Very low58.2Low189 Ų189107.5 Ų107.582%0.82259%0.585SS**  trans-64.2162.6-175-68175.5176176.40112.9N177 S178K175-N177 PolarHBondContact O-N 3.37Å; K175-S178 PolarHBondContact O-N 3.19Å
176E37.8Very low58.4Low199 Ų199103.4 Ų103.493%0.9356%0.564SS**THydrogen-bonded Turntrans-60.133.9-179.3-60.3172.2118.400116.9
177N37.6Very low58.5Low160 Ų160102.3 Ų102.386%0.85656%0.559SS**THydrogen-bonded Turntrans-147.95.8170.2-98.1-45.5000114K175 R179K175-N177 PolarHBondContact O-N 3.37Å; N177-R179 VanDerWaalsContact C-N 3.34Å; N177-R179 PolarHBondContact O-N 3.21Å
178S40Very low58.8Low78 Ų78101.5 Ų101.555%0.54556%0.56SS.*  trans-86.774.8178.5-70.70000112.4I174 K175 C180I174-S178 VanDerWaalsContact CG2-CB 3.46Å; I174-S178 WeakPolarHBondContact CG2-OG 3.11Å; K175-S178 PolarHBondContact O-N 3.19Å; S178-C180 PolarHBondContact O-N 3.23Å
179R45.6Very low59.7Low169 Ų16999.7 Ų99.764%0.63855%0.546SS*.  trans-53130.7133.8-65.3-179.3-179.4-175.1-1.5105.9N177 P181N177-R179 VanDerWaalsContact C-N 3.34Å; N177-R179 PolarHBondContact O-N 3.21Å; R179-P181 WeakPolarHBondContact O-CD 3.45Å
180C46.3Very low61.3Low80 Ų8096.3 Ų96.354%0.54151%0.511SS..  trans-83.699.3157.1-171.50000104.7S178S178-C180 PolarHBondContact O-N 3.23Å
181P58.8Low63.1Low84 Ų8495.1 Ų95.155%0.54551%0.506SS..PPolyproline II helixtrans-65.8145.9-179.1-7.826.4000107.2R179 D330R179-P181 WeakPolarHBondContact O-CD 3.45Å; P181-D330 WeakPolarHBondContact CA-OD2 3.34Å
182L72.4Confident65Low10 Ų1096.1 Ų96.15%0.05250%0.498CS..PPolyproline II helixtrans-52.2146.6160.5-67.2177.7000109.2L90 E184 V186 I187 D330 F331L90-L182 HydrophobicContact CD1-CD2 4.41Å; L90-L182 HydrophobicContact CD2-CD2 3.48Å; L90-L182 VanDerWaalsContact CD2-CD2 3.48Å; L182-E184 PolarHBondContact O-N 3.1Å; L182-V186 HydrophobicContact CB-CG1 4.47Å; L182-V186 HydrophobicContact CD1-CG1 4.28Å; L182-V186 HydrophobicContact CD2-CG1 4.45Å; L182-I187 HydrophobicContact CB-CD1 4.09Å; L182-I187 HydrophobicContact CB-CG1 3.61Å; L182-I187 HydrophobicContact CD1-CG1 4.48Å; L182-I187 WeakPolarHBondContact O-CD1 3.32Å; L182-D330 HydrophobicContact CB-CB 4.43Å; L182-D330 HydrophobicContact CD1-CB 3.64Å; L182-D330 HydrophobicContact CG-CB 3.87Å; L182-D330 PolarHBondContact N-OD2 3.19Å; L182-F331 HydrophobicContact CD1-CD1 3.52Å; L182-F331 HydrophobicContact CD1-CD2 4.03Å; L182-F331 HydrophobicContact CD1-CE1 3.36Å; L182-F331 HydrophobicContact CD1-CE2 3.89Å; L182-F331 HydrophobicContact CD1-CG 3.84Å; L182-F331 HydrophobicContact CD1-CZ 3.55Å; L182-F331 HydrophobicContact CD2-CE2 3.96Å; L182-F331 HydrophobicContact CD2-CZ 3.97Å; L182-F331 HydrophobicContact CG-CZ 4.44Å
183N80.6Confident67.6Low94 Ų9493.3 Ų93.350%0.50347%0.47SS..PPolyproline II helixtrans-55.1139.7171.6179.919.1000109E185 V186 I187N183-E185 PolarHBondContact ND2-OE2 3.28Å; N183-E185 PolarHBondContact O-N 3.47Å; N183-E185 VanDerWaalsContact O-N 3.1Å; N183-V186 HydrophobicContact CB-CG2 4.23Å; N183-V186 WeakPolarHBondContact O-CA 3.37Å; N183-V186 WeakPolarHBondContact O-CB 3.46Å; N183-V186 PolarHBondContact O-N 3.24Å; N183-I187 PolarHBondContact O-N 3.19Å
184E83.4Confident70.2Confident126 Ų12686.4 Ų86.459%0.58943%0.427SS*.Hα-helixtrans-54.1-34.5-178.3-77.3-72175.500111.9L182 I187 V188L182-E184 PolarHBondContact O-N 3.1Å; E184-I187 PolarHBondContact O-N 3.32Å; E184-V188 WeakPolarHBondContact O-CB 3.47Å; E184-V188 VanDerWaalsContact O-CG2 3.29Å; E184-V188 WeakPolarHBondContact O-CG2 3.35Å; E184-V188 PolarHBondContact O-N 2.87Å
185E85.4Confident72.9Confident141 Ų14181.5 Ų81.566%0.65941%0.405SS*.Hα-helixtrans-61-44.7174.3-64170.1149.600112N183 V188 Q189N183-E185 PolarHBondContact ND2-OE2 3.28Å; N183-E185 PolarHBondContact O-N 3.47Å; N183-E185 VanDerWaalsContact O-N 3.1Å; E185-V188 PolarHBondContact O-N 2.89Å; E185-Q189 WeakPolarHBondContact O-CG 3.26Å; E185-Q189 PolarHBondContact O-N 3.43Å
186V88Confident75.7Confident7 Ų773.2 Ų73.24%0.04237%0.37CS..Hα-helixtrans-67.7-37.7176.61790000110.9F79 L182 N183 Q189 A190 F331F79-V186 HydrophobicContact CD1-CG1 4.44Å; L182-V186 HydrophobicContact CB-CG1 4.47Å; L182-V186 HydrophobicContact CD1-CG1 4.28Å; L182-V186 HydrophobicContact CD2-CG1 4.45Å; N183-V186 HydrophobicContact CB-CG2 4.23Å; N183-V186 WeakPolarHBondContact O-CA 3.37Å; N183-V186 WeakPolarHBondContact O-CB 3.46Å; N183-V186 PolarHBondContact O-N 3.24Å; V186-Q189 PolarHBondContact O-N 2.97Å; V186-A190 WeakPolarHBondContact O-CB 3.4Å; V186-A190 PolarHBondContact O-N 3.39Å; V186-F331 HydrophobicContact CG1-CE1 3.93Å; V186-F331 HydrophobicContact CG1-CZ 3.81Å
187I88.2Confident78.4Confident15 Ų1563.8 Ų63.88%0.07733%0.326CS..Hα-helixtrans-62.6-43.3173.9-66177000110.7L182 N183 E184 R191 I334L182-I187 HydrophobicContact CB-CD1 4.09Å; L182-I187 HydrophobicContact CB-CG1 3.61Å; L182-I187 HydrophobicContact CD1-CG1 4.48Å; L182-I187 WeakPolarHBondContact O-CD1 3.32Å; N183-I187 PolarHBondContact O-N 3.19Å; E184-I187 PolarHBondContact O-N 3.32Å; I187-R191 WeakPolarHBondContact O-CB 3.45Å; I187-R191 VanDerWaalsContact O-CG 3.3Å; I187-R191 WeakPolarHBondContact O-CG 3.27Å; I187-R191 PolarHBondContact O-N 2.99Å; I187-I334 HydrophobicContact CG2-CD1 4.16Å
188V88.8Confident81.1Confident73 Ų7356.6 Ų56.644%0.44229%0.288SS..Hα-helixtrans-64.8-46.6177.81680000111.1E184 E185 R191 K192E184-V188 WeakPolarHBondContact O-CB 3.47Å; E184-V188 VanDerWaalsContact O-CG2 3.29Å; E184-V188 WeakPolarHBondContact O-CG2 3.35Å; E184-V188 PolarHBondContact O-N 2.87Å; E185-V188 PolarHBondContact O-N 2.89Å; V188-R191 PolarHBondContact O-N 2.87Å; V188-K192 PolarHBondContact O-N 3.12Å
189Q90.1Very high83.6Confident32 Ų3255.1 Ų55.115%0.1527%0.272CS..Hα-helixtrans-67.6-40.7177.9-60.9-6324.700111.9D30 E185 V186 R191 K192 I193D30-Q189 PolarHBondContact OD1-NE2 3.12Å; E185-Q189 WeakPolarHBondContact O-CG 3.26Å; E185-Q189 PolarHBondContact O-N 3.43Å; V186-Q189 PolarHBondContact O-N 2.97Å; Q189-R191 VanDerWaalsContact C-N 3.31Å; Q189-R191 PolarHBondContact O-N 3.01Å; Q189-K192 WeakPolarHBondContact O-CB 3.47Å; Q189-K192 PolarHBondContact O-N 2.9Å; Q189-K192 VanDerWaalsContact OE1-CE 3.27Å; Q189-I193 HydrophobicContact CB-CD1 4.31Å; Q189-I193 VanDerWaalsContact O-CG1 3.3Å; Q189-I193 WeakPolarHBondContact O-CG1 3.08Å; Q189-I193 PolarHBondContact O-N 3.27Å
190A92.1Very high86Confident0 Ų047.2 Ų47.20%024%0.242CC..Hα-helixtrans-56.6-43.4173.200000112.1L78 V186 K192 I193 F194 F331 I334L78-A190 HydrophobicContact CD1-CB 3.72Å; V186-A190 WeakPolarHBondContact O-CB 3.4Å; V186-A190 PolarHBondContact O-N 3.39Å; A190-K192 VanDerWaalsContact C-N 3.27Å; A190-K192 PolarHBondContact O-N 2.97Å; A190-I193 PolarHBondContact O-N 2.71Å; A190-F194 HydrophobicContact CB-CD1 4.18Å; A190-F194 HydrophobicContact CB-CE1 4.03Å; A190-F194 HydrophobicContact CB-CZ 4.49Å; A190-F194 VanDerWaalsContact O-CB 3.27Å; A190-F194 WeakPolarHBondContact O-CB 3.29Å; A190-F194 VanDerWaalsContact O-CD1 3.31Å; A190-F194 WeakPolarHBondContact O-CD1 3.32Å; A190-F194 WeakPolarHBondContact O-CG 3.38Å; A190-F194 PolarHBondContact O-N 2.77Å; A190-F331 HydrophobicContact CB-CD1 4.14Å; A190-F331 HydrophobicContact CB-CE1 4.01Å; A190-I334 HydrophobicContact CB-CD1 3.85Å; A190-I334 HydrophobicContact CB-CG2 4.38Å
191R91.4Very high88.3Confident135 Ų13544 Ų4451%0.50922%0.219SC..Hα-helixtrans-65.1-22.6176.1-76.7173.8175.21543.1114.3I187 V188 Q189 P195 I334I187-R191 WeakPolarHBondContact O-CB 3.45Å; I187-R191 VanDerWaalsContact O-CG 3.3Å; I187-R191 WeakPolarHBondContact O-CG 3.27Å; I187-R191 PolarHBondContact O-N 2.99Å; V188-R191 PolarHBondContact O-N 2.87Å; Q189-R191 VanDerWaalsContact C-N 3.31Å; Q189-R191 PolarHBondContact O-N 3.01Å; R191-P195 VanDerWaalsContact O-CD 3.3Å; R191-P195 WeakPolarHBondContact O-CD 3.47Å; R191-P195 WeakPolarHBondContact O-CG 3.43Å; R191-I334 HydrophobicContact CG-CD1 4.31Å; R191-I334 HydrophobicContact CG-CG1 4.25Å; R191-I334 HydrophobicContact CG-CG2 4.04Å
192K88.9Confident90Very high86 Ų8640 Ų4037%0.37419%0.193SC..Hα-helixtrans-82.4-46.5169.8-62.2-177.7-164.3161.60112D30 V188 Q189 A190 S196D30-K192 IonicContact OD1-NZ 3.36Å; D30-K192 PolarHBondContact OD1-NZ 3.42Å; V188-K192 PolarHBondContact O-N 3.12Å; Q189-K192 WeakPolarHBondContact O-CB 3.47Å; Q189-K192 PolarHBondContact O-N 2.9Å; Q189-K192 VanDerWaalsContact OE1-CE 3.27Å; A190-K192 VanDerWaalsContact C-N 3.27Å; A190-K192 PolarHBondContact O-N 2.97Å; K192-S196 PolarHBondContact O-OG 2.78Å
193I92.6Very high91Very high0 Ų041.6 Ų41.60%020%0.2CC..Hα-helixtrans-73-47.3-171.3-64.8163.4000111.3F35 L74 Y77 L78 Q189 A190 S196 V197F35-I193 HydrophobicContact CE1-CB 4.27Å; F35-I193 HydrophobicContact CE1-CG1 4.11Å; F35-I193 HydrophobicContact CE1-CG2 4.3Å; F35-I193 HydrophobicContact CZ-CG1 4.14Å; F35-I193 HydrophobicContact CZ-CG2 4.47Å; L74-I193 HydrophobicContact CD2-CG2 4.41Å; Y77-I193 HydrophobicContact CD1-CD1 3.44Å; Y77-I193 VanDerWaalsContact CD1-CD1 3.44Å; Y77-I193 HydrophobicContact CD1-CG1 3.61Å; Y77-I193 HydrophobicContact CE1-CD1 3.84Å; Y77-I193 HydrophobicContact CE1-CG1 3.56Å; Y77-I193 HydrophobicContact CG-CD1 4.12Å; L78-I193 HydrophobicContact CB-CD1 3.86Å; L78-I193 HydrophobicContact CD1-CD1 3.99Å; Q189-I193 HydrophobicContact CB-CD1 4.31Å; Q189-I193 VanDerWaalsContact O-CG1 3.3Å; Q189-I193 WeakPolarHBondContact O-CG1 3.08Å; Q189-I193 PolarHBondContact O-N 3.27Å; A190-I193 PolarHBondContact O-N 2.71Å; I193-S196 WeakPolarHBondContact O-CB 3.24Å; I193-S196 PolarHBondContact O-N 2.85Å; I193-V197 HydrophobicContact CG2-CG2 3.8Å; I193-V197 WeakPolarHBondContact O-CG2 3.44Å; I193-V197 PolarHBondContact O-N 2.98Å
194F94.6Very high91.7Very high0 Ų037.2 Ų37.20%018%0.177CC..Hα-helixtrans-61.8-48-168.8-79.235.8000112.6L78 A190 S196 V197 I198 M321 I324 F331 I334 F335L78-F194 HydrophobicContact CD1-CE1 4.01Å; L78-F194 HydrophobicContact CD2-CE1 4.47Å; A190-F194 HydrophobicContact CB-CD1 4.18Å; A190-F194 HydrophobicContact CB-CE1 4.03Å; A190-F194 HydrophobicContact CB-CZ 4.49Å; A190-F194 VanDerWaalsContact O-CB 3.27Å; A190-F194 WeakPolarHBondContact O-CB 3.29Å; A190-F194 VanDerWaalsContact O-CD1 3.31Å; A190-F194 WeakPolarHBondContact O-CD1 3.32Å; A190-F194 WeakPolarHBondContact O-CG 3.38Å; A190-F194 PolarHBondContact O-N 2.77Å; F194-S196 VanDerWaalsContact C-N 3.28Å; F194-S196 PolarHBondContact O-N 2.69Å; F194-V197 PolarHBondContact O-N 2.9Å; F194-I198 HydrophobicContact CB-CD1 4.21Å; F194-I198 WeakPolarHBondContact O-CB 3.48Å; F194-I198 VanDerWaalsContact O-CD1 3.3Å; F194-I198 WeakPolarHBondContact O-CD1 3.45Å; F194-I198 WeakPolarHBondContact O-CG1 3.22Å; F194-I198 PolarHBondContact O-N 2.68Å; F194-M321 HydrophobicContact CD1-CE 4.21Å; F194-M321 HydrophobicContact CD1-SD 4.44Å; F194-M321 HydrophobicContact CD2-CE 4.43Å; F194-M321 HydrophobicContact CD2-SD 3.99Å; F194-M321 HydrophobicContact CE1-CE 4.45Å; F194-M321 HydrophobicContact CE1-SD 4.24Å; F194-M321 HydrophobicContact CE2-SD 3.77Å; F194-M321 HydrophobicContact CG-CE 4.2Å; F194-M321 HydrophobicContact CG-SD 4.32Å; F194-M321 HydrophobicContact CZ-SD 3.91Å; F194-I324 HydrophobicContact CE1-CG2 4.34Å; F194-I324 HydrophobicContact CZ-CG2 3.81Å; F194-F331 HydrophobicContact CE1-CD1 4.28Å; F194-F331 HydrophobicContact CE2-CB 4.14Å; F194-F331 HydrophobicContact CE2-CD1 4.26Å; F194-F331 WeakPolarHBondContact CE2-O 3.29Å; F194-F331 HydrophobicContact CZ-CB 4.09Å; F194-F331 AromaticContact CZ-CD1 3.58Å; F194-F331 HydrophobicContact CZ-CD1 3.58Å; F194-F331 HydrophobicContact CZ-CE1 4.33Å; F194-F331 HydrophobicContact CZ-CG 4.08Å; F194-I334 HydrophobicContact CB-CG2 4.17Å; F194-I334 HydrophobicContact CD2-CB 4.36Å; F194-I334 HydrophobicContact CD2-CG2 3.89Å; F194-I334 HydrophobicContact CG-CG2 4.11Å; F194-F335 HydrophobicContact CD2-CB 3.92Å; F194-F335 HydrophobicContact CE2-CB 4.14Å
195P93.3Very high92.1Very high34 Ų3432.1 Ų32.122%0.22116%0.155CC..Hα-helixtrans-57.4-41.1177-24.534.5000113R191 K199 A338R191-P195 VanDerWaalsContact O-CD 3.3Å; R191-P195 WeakPolarHBondContact O-CD 3.47Å; R191-P195 WeakPolarHBondContact O-CG 3.43Å; P195-K199 WeakPolarHBondContact O-CB 3.38Å; P195-K199 PolarHBondContact O-N 3.42Å; P195-A338 HydrophobicContact CB-CB 4.39Å; P195-A338 HydrophobicContact CG-CB 3.96Å
196S92.8Very high92.5Very high15 Ų1526.3 Ų26.311%0.10513%0.128CC..Hα-helixtrans-66.1-44.8-179.8-57.50000112.1K192 I193 F194 Y200K192-S196 PolarHBondContact O-OG 2.78Å; I193-S196 WeakPolarHBondContact O-CB 3.24Å; I193-S196 PolarHBondContact O-N 2.85Å; F194-S196 VanDerWaalsContact C-N 3.28Å; F194-S196 PolarHBondContact O-N 2.69Å; S196-Y200 PolarHBondContact O-N 3.33Å
197V94.8Very high92.8Very high1 Ų129.4 Ų29.41%0.00614%0.139CC..Hα-helixtrans-67.3-46.3177.2167.80000111.3F39 I193 F194 K199 Y200 V201 L317 W320 M321F39-V197 HydrophobicContact CE1-CG2 4.05Å; F39-V197 HydrophobicContact CZ-CG2 4Å; I193-V197 HydrophobicContact CG2-CG2 3.8Å; I193-V197 WeakPolarHBondContact O-CG2 3.44Å; I193-V197 PolarHBondContact O-N 2.98Å; F194-V197 PolarHBondContact O-N 2.9Å; V197-K199 VanDerWaalsContact C-N 3.34Å; V197-K199 PolarHBondContact O-N 3.15Å; V197-Y200 PolarHBondContact O-N 3.21Å; V197-V201 HydrophobicContact CG1-CG2 4.47Å; V197-V201 WeakPolarHBondContact O-CG2 3.26Å; V197-V201 PolarHBondContact O-N 3.36Å; V197-L317 HydrophobicContact CG1-CD1 3.95Å; V197-L317 HydrophobicContact CG1-CD2 3.85Å; V197-L317 HydrophobicContact CG1-CG 3.75Å; V197-W320 HydrophobicContact CG1-CZ3 4.48Å; V197-M321 HydrophobicContact CB-CE 3.95Å; V197-M321 HydrophobicContact CG1-CE 3.43Å; V197-M321 VanDerWaalsContact CG1-CE 3.43Å
198I94.9Very high92.8Very high8 Ų834.8 Ų34.84%0.04116%0.164CC..Hα-helixtrans-63.5-42179.5-64160.8000110.1F194 V201 V202 F335 A338 L351F194-I198 HydrophobicContact CB-CD1 4.21Å; F194-I198 WeakPolarHBondContact O-CB 3.48Å; F194-I198 VanDerWaalsContact O-CD1 3.3Å; F194-I198 WeakPolarHBondContact O-CD1 3.45Å; F194-I198 WeakPolarHBondContact O-CG1 3.22Å; F194-I198 PolarHBondContact O-N 2.68Å; I198-V201 PolarHBondContact O-N 2.8Å; I198-V202 HydrophobicContact CG2-CG2 4.08Å; I198-V202 WeakPolarHBondContact O-CB 3.45Å; I198-V202 WeakPolarHBondContact O-CG2 3.47Å; I198-V202 PolarHBondContact O-N 2.61Å; I198-F335 HydrophobicContact CD1-CD2 3.49Å; I198-F335 VanDerWaalsContact CD1-CD2 3.49Å; I198-F335 HydrophobicContact CD1-CE2 3.81Å; I198-F335 HydrophobicContact CD1-CG 4.16Å; I198-F335 HydrophobicContact CG1-CD2 3.87Å; I198-F335 HydrophobicContact CG1-CE2 3.74Å; I198-A338 HydrophobicContact CD1-CB 3.61Å; I198-L351 HydrophobicContact CG2-CB 4.39Å; I198-L351 HydrophobicContact CG2-CD1 3.83Å
199K92.9Very high92.9Very high48 Ų4836.9 Ų36.921%0.20917%0.169CC..Hα-helixtrans-58.8-50.2176.9-173.7166-176.8162.80111.6Y36 P195 V197 V201 V202 E203 E343Y36-K199 HydrophobicContact CE1-CD 4.31Å; Y36-K199 HydrophobicContact CE2-CB 4.12Å; Y36-K199 HydrophobicContact CE2-CD 4.18Å; Y36-K199 HydrophobicContact CE2-CG 4.13Å; P195-K199 WeakPolarHBondContact O-CB 3.38Å; P195-K199 PolarHBondContact O-N 3.42Å; V197-K199 VanDerWaalsContact C-N 3.34Å; V197-K199 PolarHBondContact O-N 3.15Å; K199-V201 PolarHBondContact O-N 2.71Å; K199-V202 PolarHBondContact O-N 2.82Å; K199-E203 WeakPolarHBondContact CE-OE1 3.33Å; K199-E203 HydrophobicContact CG-CG 4.36Å; K199-E203 WeakPolarHBondContact CG-OE1 3.38Å; K199-E203 IonicContact NZ-OE1 2.81Å; K199-E203 WeakPolarHBondContact O-CB 3.13Å; K199-E203 VanDerWaalsContact O-CG 3.32Å; K199-E203 WeakPolarHBondContact O-CG 3.33Å; K199-E203 PolarHBondContact O-N 3.11Å; K199-E343 IonicContact NZ-OE1 3.9Å; K199-E343 PolarHBondContact NZ-OE1 3.02Å
200Y95.1Very high92.9Very high3 Ų337.7 Ų37.71%0.01217%0.172CC..Hα-helixtrans-58.6-44.9174.8172.9-86.7000112.8L40 L43 S196 V197 M204 L217 H310 F313 A314 L317L40-Y200 HydrophobicContact CD2-CD2 3.58Å; L40-Y200 HydrophobicContact CD2-CE2 4.42Å; L40-Y200 HydrophobicContact CD2-CG 4.4Å; L43-Y200 HydrophobicContact CD1-CD1 4.07Å; L43-Y200 HydrophobicContact CD1-CD2 3.67Å; L43-Y200 HydrophobicContact CD1-CE1 4.01Å; L43-Y200 HydrophobicContact CD1-CE2 3.55Å; L43-Y200 HydrophobicContact CD1-CG 3.93Å; S196-Y200 PolarHBondContact O-N 3.33Å; V197-Y200 PolarHBondContact O-N 3.21Å; Y200-M204 HydrophobicContact CD2-CG 4.07Å; Y200-M204 HydrophobicContact CE1-CG 4.16Å; Y200-M204 HydrophobicContact CE2-CG 3.57Å; Y200-M204 WeakPolarHBondContact O-CB 3.23Å; Y200-M204 PolarHBondContact O-N 3.4Å; Y200-L217 HydrophobicContact CE2-CD1 4.01Å; Y200-H310 AromaticContact CE2-ND1 3.94Å; Y200-H310 AromaticContact CZ-ND1 3.82Å; Y200-H310 WeakPolarHBondContact OH-CB 3.37Å; Y200-H310 PolarHBondContact OH-ND1 3.19Å; Y200-H310 PolarHBondContact OH-O 3.3Å; Y200-H310 VanDerWaalsContact OH-O 3.12Å; Y200-F313 AromaticContact CE1-CD1 3.72Å; Y200-F313 HydrophobicContact CE1-CD1 3.72Å; Y200-F313 AromaticContact CE1-CE1 3.97Å; Y200-F313 HydrophobicContact CE1-CE1 3.97Å; Y200-F313 AromaticContact CZ-CD1 3.91Å; Y200-A314 HydrophobicContact CE1-CB 4.13Å; Y200-L317 HydrophobicContact CD1-CD2 3.73Å; Y200-L317 HydrophobicContact CE1-CD2 4.17Å
201V95.6Very high92.6Very high11 Ų1141.8 Ų41.87%0.06719%0.19CC..Hα-helixtrans-61.2-48.2178.7170.40000110.4V197 I198 K199 T205 L317V197-V201 HydrophobicContact CG1-CG2 4.47Å; V197-V201 WeakPolarHBondContact O-CG2 3.26Å; V197-V201 PolarHBondContact O-N 3.36Å; I198-V201 PolarHBondContact O-N 2.8Å; K199-V201 PolarHBondContact O-N 2.71Å; V201-T205 WeakPolarHBondContact O-CB 3.24Å; V201-T205 PolarHBondContact O-N 2.65Å; V201-T205 PolarHBondContact O-OG1 3.14Å; V201-L317 HydrophobicContact CG2-CB 4.11Å; V201-L317 HydrophobicContact CG2-CD2 3.86Å; V201-L317 HydrophobicContact CG2-CG 3.93Å
202V94.1Very high92.5Very high0 Ų039.8 Ų39.80%019%0.187CC..Hα-helixtrans-59.6-54178.5173.50000110.5I198 K199 M204 T205 I206 L351 R354 L355I198-V202 HydrophobicContact CG2-CG2 4.08Å; I198-V202 WeakPolarHBondContact O-CB 3.45Å; I198-V202 WeakPolarHBondContact O-CG2 3.47Å; I198-V202 PolarHBondContact O-N 2.61Å; K199-V202 PolarHBondContact O-N 2.82Å; V202-M204 PolarHBondContact O-N 3.37Å; V202-T205 PolarHBondContact O-N 3.21Å; V202-I206 HydrophobicContact CG1-CD1 4.13Å; V202-I206 WeakPolarHBondContact O-CG1 3.28Å; V202-I206 PolarHBondContact O-N 3.45Å; V202-I206 VanDerWaalsContact O-N 3.09Å; V202-L351 HydrophobicContact CB-CD2 4.34Å; V202-L351 HydrophobicContact CG1-CD2 4.14Å; V202-L351 HydrophobicContact CG2-CB 3.99Å; V202-L351 HydrophobicContact CG2-CD2 4.29Å; V202-R354 HydrophobicContact CG1-CB 4.35Å; V202-L355 HydrophobicContact CB-CG 4.47Å; V202-L355 HydrophobicContact CG1-CD2 4.48Å; V202-L355 HydrophobicContact CG1-CG 4.23Å; V202-L355 HydrophobicContact CG2-CD1 3.63Å; V202-L355 HydrophobicContact CG2-CD2 4.49Å; V202-L355 HydrophobicContact CG2-CG 3.96Å
203E93.1Very high92.5Very high44 Ų4436.1 Ų36.121%0.20617%0.171CC..Hα-helixtrans-62.7-45.2-173.9-73.5173.9167.800112.3Y36 K199 W207Y36-E203 PolarHBondContact OH-OE2 2.73Å; K199-E203 WeakPolarHBondContact CE-OE1 3.33Å; K199-E203 HydrophobicContact CG-CG 4.36Å; K199-E203 WeakPolarHBondContact CG-OE1 3.38Å; K199-E203 IonicContact NZ-OE1 2.81Å; K199-E203 WeakPolarHBondContact O-CB 3.13Å; K199-E203 VanDerWaalsContact O-CG 3.32Å; K199-E203 WeakPolarHBondContact O-CG 3.33Å; K199-E203 PolarHBondContact O-N 3.11Å; E203-W207 WeakPolarHBondContact O-CB 3.09Å; E203-W207 PolarHBondContact O-N 2.92Å
204M94.8Very high92.3Very high2 Ų236.7 Ų36.71%0.0118%0.175CC..Hα-helixtrans-72.4-32.1177.2-70.6-49-42.700112.9Y200 V202 I206 W207 L213 P214 L217 H310 Q311 A314Y200-M204 HydrophobicContact CD2-CG 4.07Å; Y200-M204 HydrophobicContact CE1-CG 4.16Å; Y200-M204 HydrophobicContact CE2-CG 3.57Å; Y200-M204 WeakPolarHBondContact O-CB 3.23Å; Y200-M204 PolarHBondContact O-N 3.4Å; V202-M204 PolarHBondContact O-N 3.37Å; M204-I206 VanDerWaalsContact C-N 3.33Å; M204-W207 HydrophobicContact CE-CB 4.11Å; M204-W207 HydrophobicContact CE-CG 4.13Å; M204-L213 HydrophobicContact CE-CD2 4.02Å; M204-L213 HydrophobicContact SD-CD2 4.49Å; M204-P214 HydrophobicContact SD-CG 3.91Å; M204-L217 HydrophobicContact SD-CD1 3.73Å; M204-H310 HydrophobicContact CE-CB 3.73Å; M204-H310 HydrophobicContact CG-CB 4.33Å; M204-H310 HydrophobicContact SD-CB 4.23Å; M204-Q311 HydrophobicContact CE-CG 4.33Å; M204-Q311 WeakPolarHBondContact O-CG 3.49Å; M204-A314 HydrophobicContact CB-CB 3.96Å
205T93.4Very high91.9Very high20 Ų2041.4 Ų41.412%0.12321%0.205CC..Hα-helixtrans-69-29.7177.5-68.20000112.8V201 V202 L355 L362 A366V201-T205 WeakPolarHBondContact O-CB 3.24Å; V201-T205 PolarHBondContact O-N 2.65Å; V201-T205 PolarHBondContact O-OG1 3.14Å; V202-T205 PolarHBondContact O-N 3.21Å; T205-L355 HydrophobicContact CG2-CD2 4.17Å; T205-L362 HydrophobicContact CG2-CD1 4.04Å; T205-L362 HydrophobicContact CG2-CD2 3.66Å; T205-L362 WeakPolarHBondContact O-CD2 3.5Å; T205-A366 HydrophobicContact CG2-CB 4.14Å
206I93.4Very high91.5Very high19 Ų1945 Ų4510%0.09722%0.219CC..THydrogen-bonded Turntrans-103.613179.476.3-176.1000114.1V202 M204 E208 L355 W358V202-I206 HydrophobicContact CG1-CD1 4.13Å; V202-I206 WeakPolarHBondContact O-CG1 3.28Å; V202-I206 PolarHBondContact O-N 3.45Å; V202-I206 VanDerWaalsContact O-N 3.09Å; M204-I206 VanDerWaalsContact C-N 3.33Å; I206-E208 PolarHBondContact O-N 3.13Å; I206-L355 HydrophobicContact CG2-CD2 4.12Å; I206-W358 HydrophobicContact CB-CD2 3.6Å; I206-W358 HydrophobicContact CB-CE3 3.95Å; I206-W358 HydrophobicContact CB-CG 3.83Å; I206-W358 HydrophobicContact CB-CZ2 4.45Å; I206-W358 HydrophobicContact CB-CZ3 4.49Å; I206-W358 HydrophobicContact CG2-CB 3.71Å; I206-W358 HydrophobicContact CG2-CD2 3.74Å; I206-W358 HydrophobicContact CG2-CE3 4.14Å; I206-W358 HydrophobicContact CG2-CG 3.49Å; I206-W358 VanDerWaalsContact CG2-CG 3.49Å
207W93.9Very high91.3Very high71 Ų7144.6 Ų44.627%0.26922%0.216SC..  trans-72.6113.2-175.6-166.6-102.7000112.2E203 M204 E209 E212 P214 Q311E203-W207 WeakPolarHBondContact O-CB 3.09Å; E203-W207 PolarHBondContact O-N 2.92Å; M204-W207 HydrophobicContact CE-CB 4.11Å; M204-W207 HydrophobicContact CE-CG 4.13Å; W207-E209 HydrophobicContact CZ2-CB 4.18Å; W207-E209 HydrophobicContact CZ2-CG 4.27Å; W207-E212 PolarHBondContact NE1-O 3.26Å; W207-P214 HydrophobicContact CD2-CG 4.09Å; W207-P214 HydrophobicContact CE3-CG 3.88Å; W207-P214 HydrophobicContact CH2-CB 4.05Å; W207-P214 HydrophobicContact CH2-CG 3.74Å; W207-P214 HydrophobicContact CZ2-CB 4.47Å; W207-P214 HydrophobicContact CZ2-CG 3.94Å; W207-P214 VanDerWaalsContact CZ2-N 3.35Å; W207-P214 HydrophobicContact CZ3-CB 4.27Å; W207-P214 HydrophobicContact CZ3-CG 3.7Å; W207-Q311 PolarHBondContact O-NE2 2.92Å
208E89.4Confident90.8Very high128 Ų12848.7 Ų48.760%0.59824%0.235SC*.  trans-81.2-28.8-179-74.3-171.7158.200114.7I206 E210 W358 K361I206-E208 PolarHBondContact O-N 3.13Å; E208-E210 PolarHBondContact O-N 2.95Å; E208-W358 HydrophobicContact CG-CH2 3.35Å; E208-W358 HydrophobicContact CG-CZ2 3.89Å; E208-W358 HydrophobicContact CG-CZ3 4.41Å; E208-W358 WeakPolarHBondContact OE1-CH2 3.27Å; E208-W358 WeakPolarHBondContact OE1-CZ2 3.44Å; E208-K361 IonicContact OE1-NZ 2.83Å; E208-K361 PolarHBondContact OE1-NZ 3.27Å
209E90.9Very high89.7Confident118 Ų11851.5 Ų51.555%0.55125%0.25SC*.  trans-70.6117.3-169.2-68.8-66.9165.300111.8W207 K211 I307W207-E209 HydrophobicContact CZ2-CB 4.18Å; W207-E209 HydrophobicContact CZ2-CG 4.27Å; E209-K211 VanDerWaalsContact C-N 3.28Å; E209-K211 PolarHBondContact O-N 3.42Å; E209-I307 VanDerWaalsContact O-CD1 3.25Å; E209-I307 WeakPolarHBondContact O-CD1 3.24Å
210E88.9Confident88.5Confident48 Ų4853.9 Ų53.922%0.22426%0.257CS..SBendtrans-68-23.3-177.4-68.7-173.5140.800113.5E208 K283 L303 H304E208-E210 PolarHBondContact O-N 2.95Å; E210-K283 IonicContact OE1-NZ 2.8Å; E210-K283 PolarHBondContact OE1-NZ 2.79Å; E210-L303 HydrophobicContact CB-CD2 4.19Å; E210-L303 HydrophobicContact CG-CD2 4.03Å; E210-H304 PolarHBondContact O-N 3.24Å
211K86.8Confident87.2Confident86 Ų8662.8 Ų62.837%0.37430%0.299SS..SBendtrans-121.7-23.5-161.3-68.4174.5-178.5171.80115.5E209 Y226 Y276E209-K211 VanDerWaalsContact C-N 3.28Å; E209-K211 PolarHBondContact O-N 3.42Å; K211-Y226 HydrophobicContact CG-CE1 4.46Å; K211-Y276 VanDerWaalsContact CE-CE2 3.46Å; K211-Y276 WeakPolarHBondContact CE-OH 3.4Å; K211-Y276 PolarHBondContact NZ-OH 2.76Å
212E87.8Confident85.8Confident94 Ų9467.8 Ų67.844%0.43932%0.32SS..  trans-130.5135.5-174.3-57.1-152.8147.200110.4W207 K222W207-E212 PolarHBondContact NE1-O 3.26Å; E212-K222 IonicContact OE1-NZ 2.81Å; E212-K222 PolarHBondContact OE1-NZ 2.98Å
213L89.1Confident84.8Confident9 Ų970.5 Ų70.55%0.04733%0.334CS..  trans-76164.6170.6-81.2168.9000110.6M204 L217 Q218 E306 I307 H310M204-L213 HydrophobicContact CE-CD2 4.02Å; M204-L213 HydrophobicContact SD-CD2 4.49Å; L213-L217 HydrophobicContact CB-CB 4.15Å; L213-L217 HydrophobicContact CD1-CB 4.23Å; L213-L217 HydrophobicContact CD2-CD1 4.36Å; L213-Q218 HydrophobicContact CB-CG 4.05Å; L213-Q218 PolarHBondContact O-NE2 2.8Å; L213-E306 HydrophobicContact CD1-CB 3.84Å; L213-I307 HydrophobicContact CD2-CB 4.46Å; L213-I307 HydrophobicContact CD2-CG1 3.79Å; L213-I307 HydrophobicContact CG-CG1 3.86Å; L213-H310 HydrophobicContact CD2-CB 4.23Å
214P89.5Confident84.2Confident11 Ų1176.2 Ų76.27%0.07136%0.361CS..  trans-48.3141.1163.5-23.830.8000111.2M204 W207 E216 L217 Q218M204-P214 HydrophobicContact SD-CG 3.91Å; W207-P214 HydrophobicContact CD2-CG 4.09Å; W207-P214 HydrophobicContact CE3-CG 3.88Å; W207-P214 HydrophobicContact CH2-CB 4.05Å; W207-P214 HydrophobicContact CH2-CG 3.74Å; W207-P214 HydrophobicContact CZ2-CB 4.47Å; W207-P214 HydrophobicContact CZ2-CG 3.94Å; W207-P214 VanDerWaalsContact CZ2-N 3.35Å; W207-P214 HydrophobicContact CZ3-CB 4.27Å; W207-P214 HydrophobicContact CZ3-CG 3.7Å; P214-E216 WeakPolarHBondContact CB-OE2 3.23Å; P214-E216 PolarHBondContact O-N 3.1Å; P214-L217 HydrophobicContact CG-CD1 4.13Å; P214-L217 PolarHBondContact O-N 3.41Å; P214-Q218 PolarHBondContact O-N 3.5Å
215P85.9Confident84Confident99 Ų9980.6 Ų80.664%0.64338%0.377SS*.G310 helixtrans-51.1-33.4-178.3-28.735.6000114.2L217 Q218P215-L217 PolarHBondContact O-N 3.46Å; P215-Q218 PolarHBondContact O-N 3.18Å
216E84.7Confident84Confident110 Ų11081.4 Ų81.451%0.51438%0.378SS..G310 helixtrans-69.3-17.9179.6-57.875.5-166.300113.5L40 P214L40-E216 HydrophobicContact CD1-CB 3.58Å; L40-E216 HydrophobicContact CD1-CG 4.07Å; P214-E216 WeakPolarHBondContact CB-OE2 3.23Å; P214-E216 PolarHBondContact O-N 3.1Å
217L88.5Confident84Confident7 Ų780.5 Ų80.54%0.03737%0.374CS..G310 helixtrans-105-7.6177-62.9176.6000112.9L40 A44 Y200 M204 L213 P214 P215 I219L40-L217 HydrophobicContact CB-CD2 4.12Å; L40-L217 HydrophobicContact CD2-CD2 4.19Å; L40-L217 WeakPolarHBondContact O-CD2 3.5Å; A44-L217 HydrophobicContact CB-CB 4.38Å; A44-L217 HydrophobicContact CB-CD2 3.88Å; Y200-L217 HydrophobicContact CE2-CD1 4.01Å; M204-L217 HydrophobicContact SD-CD1 3.73Å; L213-L217 HydrophobicContact CB-CB 4.15Å; L213-L217 HydrophobicContact CD1-CB 4.23Å; L213-L217 HydrophobicContact CD2-CD1 4.36Å; P214-L217 HydrophobicContact CG-CD1 4.13Å; P214-L217 PolarHBondContact O-N 3.41Å; P215-L217 PolarHBondContact O-N 3.46Å; L217-I219 VanDerWaalsContact C-N 3.28Å; L217-I219 PolarHBondContact O-N 3.19Å
218Q83.6Confident84.1Confident87 Ų8777.1 Ų77.141%0.40736%0.361SS..  trans-80.164.9178-64.6-168.823.300112.6L213 P214 P215L213-Q218 HydrophobicContact CB-CG 4.05Å; L213-Q218 PolarHBondContact O-NE2 2.8Å; P214-Q218 PolarHBondContact O-N 3.5Å; P215-Q218 PolarHBondContact O-N 3.18Å
219I72.7Confident84.3Confident67 Ų6771 Ų7134%0.34433%0.333SS..  trans-101.8-12.4-172.8-43.7-167.8000113H41 A44 L217H41-I219 HydrophobicContact CB-CD1 4.1Å; H41-I219 VanDerWaalsContact CD2-CD1 3.48Å; H41-I219 WeakPolarHBondContact CD2-CD1 3.46Å; A44-I219 HydrophobicContact CB-CB 4.26Å; A44-I219 HydrophobicContact CB-CD1 3.58Å; A44-I219 HydrophobicContact CB-CG1 3.74Å; L217-I219 VanDerWaalsContact C-N 3.28Å; L217-I219 PolarHBondContact O-N 3.19Å
220R67.8Low84.5Confident98 Ų9865.5 Ų65.537%0.3731%0.307SS..SBendtrans-108.9159.1-178.5-66.1-177.4172.9-141-11.9111.9Q45 E49 K222Q45-R220 VanDerWaalsContact O-CZ 3.25Å; Q45-R220 PolarHBondContact O-NH2 3.46Å; E49-R220 IonicContact OE1-CZ 2.75Å; E49-R220 IonicContact OE1-NH1 3.8Å; E49-R220 PolarHBondContact OE1-NH1 3.15Å; E49-R220 IonicContact OE1-NH2 3.34Å; E49-R220 PolarHBondContact OE1-NH2 3.36Å; R220-K222 PolarHBondContact O-N 3.49Å
221E67.1Low84.7Confident190 Ų19064.2 Ų64.289%0.88830%0.3SS*.PPolyproline II helixtrans-62.5129.5164.7-68.7-171.5153.200109.1N223E221-N223 PolarHBondContact O-N 3.17Å; E221-N223 VanDerWaalsContact O-N 3.15Å
222K66.8Low84.9Confident116 Ų11661.1 Ų61.150%0.50429%0.288SS..PPolyproline II helixtrans-58.1119.6-176.9-72.5-171.7177.8-174.40110.7E212 R220E212-K222 IonicContact OE1-NZ 2.81Å; E212-K222 PolarHBondContact OE1-NZ 2.98Å; R220-K222 PolarHBondContact O-N 3.49Å
223N72.8Confident84.7Confident56 Ų5657.4 Ų57.430%0.29927%0.271SS..PPolyproline II helixtrans-77.9141.2168.577.471.4000109.6E221 R225 H304 S305 E306E221-N223 PolarHBondContact O-N 3.17Å; E221-N223 VanDerWaalsContact O-N 3.15Å; N223-R225 PolarHBondContact O-N 2.9Å; N223-R225 WeakPolarHBondContact OD1-CB 3.49Å; N223-R225 PolarHBondContact OD1-N 2.65Å; N223-R225 VanDerWaalsContact OD1-N 3.09Å; N223-H304 PolarHBondContact O-NE2 2.85Å; N223-S305 PolarHBondContact ND2-OG 3.23Å; N223-S305 PolarHBondContact OD1-OG 3.4Å; N223-S305 VanDerWaalsContact OD1-OG 3.04Å; N223-E306 WeakPolarHBondContact ND2-CG 3.49Å; N223-E306 PolarHBondContact ND2-OE1 3.3Å
224E81.5Confident84.4Confident165 Ų16560.9 Ų60.977%0.77129%0.287SS*.  trans-84.435.9-179-64.5-165.5150.800113.4
225R89.2Confident84Confident93 Ų9366.5 Ų66.535%0.35131%0.312SS..  trans-105.9123.3-175.6-162.2179.6-176.6-163.9-3.4112.2F52 N223 S305F52-R225 PolarHBondContact O-NH1 3.36Å; N223-R225 PolarHBondContact O-N 2.9Å; N223-R225 WeakPolarHBondContact OD1-CB 3.49Å; N223-R225 PolarHBondContact OD1-N 2.65Å; N223-R225 VanDerWaalsContact OD1-N 3.09Å; R225-S305 WeakPolarHBondContact O-CB 3.45Å; R225-S305 PolarHBondContact O-N 2.65Å; R225-S305 PolarHBondContact O-OG 3.4Å; R225-S305 VanDerWaalsContact O-OG 3.08Å
226Y93.1Very high84.1Confident37 Ų3763.1 Ų63.115%0.14529%0.288CS..EExtended strand (participates in β ladder)trans-123.3159.3-179.5-63.8-97.8000110.5K211 A273 G274 Y276 C279 V302 L303 H304K211-Y226 HydrophobicContact CG-CE1 4.46Å; Y226-A273 WeakPolarHBondContact O-CA 3.26Å; Y226-G274 PolarHBondContact N-O 3.33Å; Y226-G274 PolarHBondContact O-N 3.1Å; Y226-Y276 AromaticContact CD1-CD2 3.76Å; Y226-Y276 HydrophobicContact CD1-CD2 3.76Å; Y226-Y276 HydrophobicContact CD2-CD2 4.49Å; Y226-Y276 AromaticContact CE1-CD2 3.77Å; Y226-Y276 HydrophobicContact CE1-CD2 3.77Å; Y226-Y276 HydrophobicContact CG-CD2 4.13Å; Y226-C279 PolarHBondContact O-SG 3.09Å; Y226-V302 HydrophobicContact CD1-CG1 4.14Å; Y226-V302 HydrophobicContact CG-CG1 4.37Å; Y226-L303 CarbonylContact C-O 3.6Å; Y226-L303 WeakPolarHBondContact CA-O 3.42Å; Y226-H304 HydrophobicContact CD1-CB 4.31Å; Y226-H304 HydrophobicContact CE1-CB 4.14Å; Y226-H304 AromaticContact CE1-CD2 3.87Å; Y226-H304 AromaticContact CZ-CD2 3.8Å
227Y94.5Very high84.3Confident1 Ų160 Ų600%0.00428%0.278CS..EExtended strand (participates in β ladder)trans-118.7134.4170.6-64.8-68.7000109.9F52 E54 M55 A270 K272 A273 V302 L303 M308F52-Y227 PolarHBondContact O-OH 3.3Å; E54-Y227 HydrophobicContact CB-CE1 4.23Å; E54-Y227 HydrophobicContact CB-CE2 4.15Å; E54-Y227 HydrophobicContact CG-CE2 4.28Å; E54-Y227 PolarHBondContact N-OH 2.91Å; M55-Y227 HydrophobicContact CG-CD1 4.49Å; M55-Y227 HydrophobicContact CG-CE1 4.21Å; Y227-A270 HydrophobicContact CD1-CB 3.92Å; Y227-A270 HydrophobicContact CG-CB 4.12Å; Y227-K272 CarbonylContact C-O 3.42Å; Y227-K272 WeakPolarHBondContact CA-O 3.29Å; Y227-A273 HydrophobicContact CD1-CB 3.54Å; Y227-A273 HydrophobicContact CE1-CB 3.51Å; Y227-V302 CarbonylContact O-C 3.59Å; Y227-V302 WeakPolarHBondContact O-CA 3.45Å; Y227-L303 PolarHBondContact N-O 3.25Å; Y227-L303 PolarHBondContact O-N 3.18Å; Y227-M308 HydrophobicContact CD2-CB 4.21Å; Y227-M308 HydrophobicContact CD2-SD 3.62Å; Y227-M308 HydrophobicContact CE2-SD 4.26Å; Y227-M308 HydrophobicContact CG-SD 3.99Å
228C95.3Very high84.5Confident0 Ų064.9 Ų64.90%030%0.297CS..EExtended strand (participates in β ladder)trans-80.3118159.7-1720000107.2A270 V271 K272 C279 V300C228-A270 WeakPolarHBondContact O-CA 3.32Å; C228-V271 HydrophobicContact CB-CG2 4.41Å; C228-V271 WeakPolarHBondContact O-CG2 3.33Å; C228-V271 PolarHBondContact O-N 3.43Å; C228-K272 HydrophobicContact CB-CB 3.9Å; C228-K272 PolarHBondContact N-O 3.03Å; C228-K272 PolarHBondContact O-N 2.86Å; C228-C279 HydrophobicContact CB-CB 4.15Å; C228-V300 WeakPolarHBondContact SG-CG1 3.39Å
229V94.6Very high84.8Confident0 Ų066.7 Ų66.70%031%0.309CS..EExtended strand (participates in β ladder)trans-115.8119.8-173.6-177.80000108.9F231 R268 R269 V300 E301 L303 M308V229-F231 HydrophobicContact CB-CE2 4.13Å; V229-F231 HydrophobicContact CG1-CD2 4.17Å; V229-F231 HydrophobicContact CG1-CE2 3.71Å; V229-F231 HydrophobicContact CG1-CZ 4.11Å; V229-R268 HydrophobicContact CG1-CB 4.07Å; V229-R268 HydrophobicContact CG1-CG 4.41Å; V229-R269 WeakPolarHBondContact CA-O 3.33Å; V229-V300 WeakPolarHBondContact O-CA 3.47Å; V229-E301 PolarHBondContact N-O 3.1Å; V229-E301 PolarHBondContact O-N 3.46Å; V229-L303 HydrophobicContact CG2-CB 4.46Å; V229-L303 HydrophobicContact CG2-CD1 4.17Å; V229-L303 HydrophobicContact CG2-CG 4.31Å; V229-M308 HydrophobicContact CG2-SD 3.93Å
230L94.9Very high85.7Confident1 Ų166.8 Ų66.81%0.00531%0.308CS..EExtended strand (participates in β ladder)trans-94.9131.3172.6173.160.4000108.6V241 L245 I263 R268 R269 V271 L298 V300L230-V241 HydrophobicContact CD2-CG1 3.95Å; L230-L245 HydrophobicContact CD2-CD1 4.14Å; L230-L245 HydrophobicContact CD2-CD2 3.78Å; L230-L245 HydrophobicContact CD2-CG 4.12Å; L230-I263 HydrophobicContact CB-CD1 4.14Å; L230-I263 HydrophobicContact CD2-CD1 3.56Å; L230-I263 HydrophobicContact CG-CD1 3.79Å; L230-R268 CarbonylContact O-C 3.58Å; L230-R268 VanDerWaalsContact O-CA 3.28Å; L230-R268 WeakPolarHBondContact O-CA 3.4Å; L230-R269 PolarHBondContact N-O 3.05Å; L230-R269 PolarHBondContact O-N 3.2Å; L230-V271 HydrophobicContact CB-CG1 4Å; L230-V271 HydrophobicContact CB-CG2 4.35Å; L230-L298 HydrophobicContact CD1-CB 3.86Å; L230-L298 HydrophobicContact CD1-CD1 4.27Å; L230-L298 HydrophobicContact CD1-CD2 4.33Å; L230-L298 HydrophobicContact CD1-CG 4.39Å; L230-V300 HydrophobicContact CB-CG2 4.47Å; L230-V300 HydrophobicContact CD1-CG2 3.66Å
231F93.2Very high86.8Confident21 Ų2162.8 Ų62.89%0.09230%0.295CS..EExtended strand (participates in β ladder)trans-98.8157.5179-70.4-105000110.8V229 R268 H299 E301V229-F231 HydrophobicContact CB-CE2 4.13Å; V229-F231 HydrophobicContact CG1-CD2 4.17Å; V229-F231 HydrophobicContact CG1-CE2 3.71Å; V229-F231 HydrophobicContact CG1-CZ 4.11Å; F231-R268 HydrophobicContact CB-CB 4.5Å; F231-R268 HydrophobicContact CD1-CB 3.66Å; F231-R268 HydrophobicContact CD1-CG 4.47Å; F231-R268 HydrophobicContact CE1-CB 4Å; F231-R268 VanDerWaalsContact CE1-CD 3.48Å; F231-R268 HydrophobicContact CE1-CG 4.38Å; F231-R268 HydrophobicContact CG-CB 4Å; F231-H299 HydrophobicContact CB-CB 4.36Å; F231-H299 AromaticContact CD2-CD2 3.81Å; F231-H299 AromaticContact CD2-NE2 3.97Å; F231-H299 AromaticContact CG-CD2 3.6Å; F231-H299 PolarHBondContact N-O 3.35Å; F231-E301 HydrophobicContact CD2-CG 4.39Å; F231-E301 HydrophobicContact CE2-CB 3.93Å; F231-E301 HydrophobicContact CE2-CG 3.76Å; F231-E301 HydrophobicContact CZ-CG 4.46Å; F231-E301 WeakPolarHBondContact CZ-OE2 3.34Å
232N90.8Very high88.1Confident21 Ų2154.4 Ų54.411%0.11226%0.256CS..PPolyproline II helixtrans-79.4128.4170.9-165.770.5000109.2E234 I263 D264 G267N232-E234 PolarHBondContact ND2-OE1 3.19Å; N232-I263 HydrophobicContact CB-CG2 3.69Å; N232-D264 WeakPolarHBondContact OD1-CA 3.32Å; N232-G267 PolarHBondContact N-O 3.29Å
233D82.3Confident89.3Confident16 Ų1653.5 Ų53.59%0.08625%0.25CC..  trans-113.5147.1156.164.266.6000107.8H235 H236 D407D233-H235 PolarHBondContact O-N 3.35Å; D233-H235 WeakPolarHBondContact OD1-CB 3.27Å; D233-H235 PolarHBondContact OD1-N 2.9Å; D233-H235 VanDerWaalsContact OD1-N 3.1Å; D233-H236 IonicContact OD1-CE1 1.95Å; D233-H236 IonicContact OD1-CG 3.73Å; D233-H236 PolarHBondContact OD1-N 3.47Å; D233-H236 IonicContact OD1-ND1 3.79Å; D233-H236 PolarHBondContact OD1-ND1 2.98Å; D233-H236 IonicContact OD2-CE1 2.75Å; D233-H236 IonicContact OD2-CG 3.11Å; D233-H236 IonicContact OD2-ND1 2.91Å; D233-H236 PolarHBondContact OD2-ND1 2.95Å; D233-D407 WeakPolarHBondContact CA-OD2 3.21Å; D233-D407 WeakPolarHBondContact CB-OD2 3.31Å
234E82.9Confident90.2Very high82 Ų8250.9 Ų50.938%0.38324%0.236SC..SBendtrans-84.716.9178-54.6-71168.300111.4N232 K364N232-E234 PolarHBondContact ND2-OE1 3.19Å; E234-K364 IonicContact OE1-NZ 2.27Å; E234-K364 PolarHBondContact OE1-NZ 3.46Å; E234-K364 IonicContact OE2-NZ 3.06Å
235H81.9Confident90.8Very high129 Ų12943 Ų4360%0.59720%0.199SC*.SBendtrans-99.7-38.8-178-71103.1000113D233 D407D233-H235 PolarHBondContact O-N 3.35Å; D233-H235 WeakPolarHBondContact OD1-CB 3.27Å; D233-H235 PolarHBondContact OD1-N 2.9Å; D233-H235 VanDerWaalsContact OD1-N 3.1Å; H235-D407 WeakPolarHBondContact CE1-CB 3.2Å; H235-D407 WeakPolarHBondContact ND1-CB 3.15Å
236H87.3Confident91.1Very high28 Ų2841.6 Ų41.613%0.1320%0.197CC..SBendtrans-83.7138.8-177.4-70.791.4000112.5D233 V241 S294 H296 L298D233-H236 IonicContact OD1-CE1 1.95Å; D233-H236 IonicContact OD1-CG 3.73Å; D233-H236 PolarHBondContact OD1-N 3.47Å; D233-H236 IonicContact OD1-ND1 3.79Å; D233-H236 PolarHBondContact OD1-ND1 2.98Å; D233-H236 IonicContact OD2-CE1 2.75Å; D233-H236 IonicContact OD2-CG 3.11Å; D233-H236 IonicContact OD2-ND1 2.91Å; D233-H236 PolarHBondContact OD2-ND1 2.95Å; H236-V241 HydrophobicContact CB-CG2 3.9Å; H236-S294 PolarHBondContact NE2-OG 2.86Å; H236-S294 VanDerWaalsContact NE2-OG 3.08Å; H236-H296 PolarHBondContact CE1-O 3Å; H236-H296 PolarHBondContact NE2-O 3.44Å; H236-L298 HydrophobicContact CB-CD2 4.03Å; H236-L298 WeakPolarHBondContact ND1-CD2 3.34Å
237S90.3Very high91Very high45 Ų4547.4 Ų47.432%0.31522%0.218SC..  trans-73.4154.2171.376.40000110.9D239 H240 V241S237-D239 PolarHBondContact O-N 3.03Å; S237-H240 WeakPolarHBondContact O-CB 3.43Å; S237-H240 PolarHBondContact O-N 2.96Å; S237-H240 PolarHBondContact OG-CD2 2.7Å; S237-H240 PolarHBondContact OG-N 2.69Å; S237-H240 PolarHBondContact OG-ND1 2.85Å; S237-H240 PolarHBondContact OG-NE2 2.99Å; S237-V241 PolarHBondContact O-N 3.14Å; S237-V241 VanDerWaalsContact O-N 3.15Å
238Y91.9Very high90.9Very high110 Ų11047.9 Ų47.943%0.43122%0.223SC..Hα-helixtrans-53.1-41.5175.5-82.1-124.4000111.3H240 V241 I242 T260 D264Y238-H240 VanDerWaalsContact C-N 3.34Å; Y238-H240 PolarHBondContact O-N 3.41Å; Y238-V241 PolarHBondContact O-N 3.08Å; Y238-I242 WeakPolarHBondContact O-CB 3.36Å; Y238-I242 WeakPolarHBondContact O-CD1 3.45Å; Y238-I242 WeakPolarHBondContact O-CG1 3.26Å; Y238-I242 PolarHBondContact O-N 3.07Å; Y238-T260 HydrophobicContact CD1-CG2 3.67Å; Y238-T260 HydrophobicContact CE1-CG2 4.22Å; Y238-T260 HydrophobicContact CG-CG2 3.91Å; Y238-D264 VanDerWaalsContact OH-CB 3.31Å; Y238-D264 WeakPolarHBondContact OH-CB 3.4Å; Y238-D264 PolarHBondContact OH-OD2 2.83Å
239D90.8Very high90.7Very high125 Ų12549.9 Ų49.967%0.66823%0.233SC*.Hα-helixtrans-63.9-35.8179.5-65.7-35000112.6S237 Y243S237-D239 PolarHBondContact O-N 3.03Å; D239-Y243 VanDerWaalsContact O-CB 3.3Å; D239-Y243 WeakPolarHBondContact O-CB 3.38Å; D239-Y243 PolarHBondContact O-N 3.38Å
240H90.3Very high90.5Very high68 Ų6857.4 Ų57.432%0.31527%0.273SS..Hα-helixtrans-68.1-43.5176-61.5173.6000111.6S237 Y238 Y243 S244 V293S237-H240 WeakPolarHBondContact O-CB 3.43Å; S237-H240 PolarHBondContact O-N 2.96Å; S237-H240 PolarHBondContact OG-CD2 2.7Å; S237-H240 PolarHBondContact OG-N 2.69Å; S237-H240 PolarHBondContact OG-ND1 2.85Å; S237-H240 PolarHBondContact OG-NE2 2.99Å; Y238-H240 VanDerWaalsContact C-N 3.34Å; Y238-H240 PolarHBondContact O-N 3.41Å; H240-Y243 PolarHBondContact O-N 3.37Å; H240-S244 WeakPolarHBondContact O-CB 3.21Å; H240-S244 PolarHBondContact O-N 3.04Å; H240-S244 PolarHBondContact O-OG 3.26Å; H240-V293 HydrophobicContact CB-CG1 4.36Å
241V92.3Very high90.3Very high15 Ų1558.1 Ų58.19%0.09128%0.278CS..Hα-helixtrans-65.1-47.7178.2-178.80000110.4L230 H236 S237 Y238 Y243 S244 L245 T260 L298L230-V241 HydrophobicContact CD2-CG1 3.95Å; H236-V241 HydrophobicContact CB-CG2 3.9Å; S237-V241 PolarHBondContact O-N 3.14Å; S237-V241 VanDerWaalsContact O-N 3.15Å; Y238-V241 PolarHBondContact O-N 3.08Å; V241-Y243 PolarHBondContact O-N 3.03Å; V241-S244 PolarHBondContact O-N 3.44Å; V241-L245 HydrophobicContact CG1-CD1 3.94Å; V241-L245 HydrophobicContact CG1-CG 4.41Å; V241-L245 WeakPolarHBondContact O-CG 3.47Å; V241-L245 PolarHBondContact O-N 3.1Å; V241-T260 HydrophobicContact CB-CG2 3.95Å; V241-T260 HydrophobicContact CG1-CG2 3.95Å; V241-L298 HydrophobicContact CG2-CD2 4.06Å
242I93.2Very high90.3Very high13 Ų1364.2 Ų64.27%0.06731%0.307CS..Hα-helixtrans-56.5-49.9176.4-70.6163.1000110.5Y238 S244 L245 Q246 L253 A256 Q257 T260Y238-I242 WeakPolarHBondContact O-CB 3.36Å; Y238-I242 WeakPolarHBondContact O-CD1 3.45Å; Y238-I242 WeakPolarHBondContact O-CG1 3.26Å; Y238-I242 PolarHBondContact O-N 3.07Å; I242-S244 PolarHBondContact O-N 3.42Å; I242-L245 PolarHBondContact O-N 3.21Å; I242-Q246 HydrophobicContact CG2-CG 4.46Å; I242-Q246 WeakPolarHBondContact O-CG 3.38Å; I242-Q246 PolarHBondContact O-N 3.13Å; I242-L253 HydrophobicContact CG2-CD1 3.5Å; I242-A256 HydrophobicContact CG2-CB 4.05Å; I242-Q257 HydrophobicContact CD1-CG 3.66Å; I242-Q257 HydrophobicContact CG1-CG 4.22Å; I242-T260 HydrophobicContact CG1-CG2 4.35Å; I242-T260 WeakPolarHBondContact CG1-OG1 3.29Å
243Y92.3Very high90.4Very high98 Ų9867.3 Ų67.338%0.38432%0.323SS..Hα-helixtrans-58.2-46.2178.9175.2-89.5000112.3D239 H240 V241 Q246 R247 V293D239-Y243 VanDerWaalsContact O-CB 3.3Å; D239-Y243 WeakPolarHBondContact O-CB 3.38Å; D239-Y243 PolarHBondContact O-N 3.38Å; H240-Y243 PolarHBondContact O-N 3.37Å; V241-Y243 PolarHBondContact O-N 3.03Å; Y243-Q246 PolarHBondContact O-N 3.06Å; Y243-R247 HydrophobicContact CD1-CG 4.41Å; Y243-R247 HydrophobicContact CE1-CG 4.03Å; Y243-R247 HydrophobicContact CE2-CG 4.23Å; Y243-R247 VanDerWaalsContact O-CG 3.3Å; Y243-R247 WeakPolarHBondContact O-CG 3.48Å; Y243-R247 PolarHBondContact O-N 2.9Å; Y243-R247 VanDerWaalsContact O-N 3.13Å; Y243-V293 HydrophobicContact CD1-CG2 3.69Å; Y243-V293 HydrophobicContact CE1-CG2 3.63Å
244S92.5Very high90.9Very high1 Ų169.4 Ų69.41%0.00734%0.343CS..Hα-helixtrans-65-42.3-178.3-56.90000111.6H240 V241 I242 R247 A248H240-S244 WeakPolarHBondContact O-CB 3.21Å; H240-S244 PolarHBondContact O-N 3.04Å; H240-S244 PolarHBondContact O-OG 3.26Å; V241-S244 PolarHBondContact O-N 3.44Å; I242-S244 PolarHBondContact O-N 3.42Å; S244-R247 PolarHBondContact O-N 2.8Å; S244-A248 WeakPolarHBondContact O-CB 3.34Å; S244-A248 PolarHBondContact O-N 2.9Å
245L93.8Very high91.3Very high0 Ų070 Ų700%035%0.345CS..Hα-helixtrans-64.6-45.2176.2-72.3173.9000112.5L230 V241 I242 R247 A248 L249 C251 A256 H259 V271 I286L230-L245 HydrophobicContact CD2-CD1 4.14Å; L230-L245 HydrophobicContact CD2-CD2 3.78Å; L230-L245 HydrophobicContact CD2-CG 4.12Å; V241-L245 HydrophobicContact CG1-CD1 3.94Å; V241-L245 HydrophobicContact CG1-CG 4.41Å; V241-L245 WeakPolarHBondContact O-CG 3.47Å; V241-L245 PolarHBondContact O-N 3.1Å; I242-L245 PolarHBondContact O-N 3.21Å; L245-R247 VanDerWaalsContact C-N 3.25Å; L245-R247 PolarHBondContact O-N 3.3Å; L245-A248 PolarHBondContact O-N 3.42Å; L245-L249 HydrophobicContact CD2-CD1 3.73Å; L245-L249 WeakPolarHBondContact O-CB 3.32Å; L245-L249 PolarHBondContact O-N 3.27Å; L245-C251 PolarHBondContact O-SG 3.21Å; L245-A256 HydrophobicContact CB-CB 4.19Å; L245-H259 HydrophobicContact CD1-CB 3.87Å; L245-V271 HydrophobicContact CD2-CB 4.21Å; L245-V271 HydrophobicContact CD2-CG1 4.01Å; L245-V271 HydrophobicContact CD2-CG2 4.37Å; L245-I286 HydrophobicContact CD2-CD1 4.27Å
246Q94.2Very high91.8Very high63 Ų6363.9 Ų63.929%0.29432%0.317SS..Hα-helixtrans-59.9-36.8177.1-72.3-160.6-81.600112.4I242 Y243 D250 C251 A256I242-Q246 HydrophobicContact CG2-CG 4.46Å; I242-Q246 WeakPolarHBondContact O-CG 3.38Å; I242-Q246 PolarHBondContact O-N 3.13Å; Y243-Q246 PolarHBondContact O-N 3.06Å; Q246-D250 WeakPolarHBondContact O-CA 3.33Å; Q246-D250 PolarHBondContact O-N 2.98Å; Q246-C251 PolarHBondContact NE2-O 3.41Å; Q246-A256 HydrophobicContact CG-CB 3.69Å
247R91.3Very high92.1Very high158 Ų15866.8 Ų66.860%0.59633%0.331SS*.Hα-helixtrans-79.6-39.1-178.1-67.3-71.6165.7-169.6-6.7113.6Y243 S244 L245 H289Y243-R247 HydrophobicContact CD1-CG 4.41Å; Y243-R247 HydrophobicContact CE1-CG 4.03Å; Y243-R247 HydrophobicContact CE2-CG 4.23Å; Y243-R247 VanDerWaalsContact O-CG 3.3Å; Y243-R247 WeakPolarHBondContact O-CG 3.48Å; Y243-R247 PolarHBondContact O-N 2.9Å; Y243-R247 VanDerWaalsContact O-N 3.13Å; S244-R247 PolarHBondContact O-N 2.8Å; L245-R247 VanDerWaalsContact C-N 3.25Å; L245-R247 PolarHBondContact O-N 3.3Å; R247-H289 HydrophobicContact CB-CB 4.39Å; R247-H289 VanDerWaalsContact CB-CD2 3.43Å; R247-H289 WeakPolarHBondContact CB-CD2 3.28Å
248A92.2Very high92.2Very high12 Ų1269.4 Ų69.410%0.09934%0.34CS..Hα-helixtrans-83-23.5-177.500000114S244 L245 D285 I286S244-A248 WeakPolarHBondContact O-CB 3.34Å; S244-A248 PolarHBondContact O-N 2.9Å; L245-A248 PolarHBondContact O-N 3.42Å; A248-D285 HydrophobicContact CB-CB 3.75Å; A248-I286 HydrophobicContact CB-CB 4.24Å; A248-I286 HydrophobicContact CB-CG1 3.47Å; A248-I286 VanDerWaalsContact CB-CG1 3.47Å
249L91.8Very high92.3Very high41 Ų4164.4 Ų64.422%0.21532%0.321CS..Hα-helixtrans-114.5-5.5-175.8-54.8174.9000114L245 C251 V271 K272 A282L245-L249 HydrophobicContact CD2-CD1 3.73Å; L245-L249 WeakPolarHBondContact O-CB 3.32Å; L245-L249 PolarHBondContact O-N 3.27Å; L249-C251 HydrophobicContact CB-CB 4.33Å; L249-C251 PolarHBondContact O-N 2.91Å; L249-V271 HydrophobicContact CD1-CB 3.87Å; L249-V271 HydrophobicContact CD1-CG2 4.16Å; L249-K272 HydrophobicContact CD2-CB 4.25Å; L249-K272 HydrophobicContact CD2-CD 4.18Å; L249-A282 HydrophobicContact CD2-CB 4.04Å
250D89.8Confident92.4Very high158 Ų15858.8 Ų58.885%0.84529%0.291SS*.  trans53.737.6-174.2-156.132.5000113Q246Q246-D250 WeakPolarHBondContact O-CA 3.33Å; Q246-D250 PolarHBondContact O-N 2.98Å
251C91.6Very high92.5Very high16 Ų1659.3 Ų59.311%0.10830%0.299CS..  trans-96.9157.9-173.665.20000114L245 Q246 L249 E255L245-C251 PolarHBondContact O-SG 3.21Å; Q246-C251 PolarHBondContact NE2-O 3.41Å; L249-C251 HydrophobicContact CB-CB 4.33Å; L249-C251 PolarHBondContact O-N 2.91Å; C251-E255 HydrophobicContact CB-CB 4.44Å; C251-E255 HydrophobicContact CB-CG 4.31Å; C251-E255 WeakPolarHBondContact CB-OE2 3.38Å
252E93.4Very high92.3Very high150 Ų15059.2 Ų59.270%0.70130%0.3SS*.  trans-69.6154.3177.7-69.7-162.4174.100112.3A254 E255 A256E252-A254 VanDerWaalsContact C-N 3.25Å; E252-A254 PolarHBondContact O-N 3.36Å; E252-E255 WeakPolarHBondContact O-CB 3.42Å; E252-E255 PolarHBondContact O-N 3.4Å; E252-A256 PolarHBondContact O-N 2.99Å
253L92.4Very high92.3Very high85 Ų8558.8 Ų58.845%0.44530%0.298SS..Hα-helixtrans-56.6-39.3-179.6177.761.8000112.5I242 E255 Q257I242-L253 HydrophobicContact CG2-CD1 3.5Å; L253-E255 VanDerWaalsContact C-N 3.34Å; L253-Q257 HydrophobicContact CD1-CG 4.28Å; L253-Q257 WeakPolarHBondContact O-CB 3.16Å; L253-Q257 VanDerWaalsContact O-CG 3.23Å; L253-Q257 WeakPolarHBondContact O-CG 3.46Å; L253-Q257 PolarHBondContact O-N 3.32Å
254A92.4Very high92.2Very high61 Ų6156.3 Ų56.350%0.50429%0.291SS..Hα-helixtrans-66.8-35.617900000112.4E252 L258E252-A254 VanDerWaalsContact C-N 3.25Å; E252-A254 PolarHBondContact O-N 3.36Å; A254-L258 VanDerWaalsContact O-CB 3.27Å; A254-L258 WeakPolarHBondContact O-CB 3.26Å; A254-L258 PolarHBondContact O-N 3.01Å
255E91.9Very high92Very high94 Ų9463.6 Ų63.644%0.43932%0.323SS..Hα-helixtrans-70-47.5176.5-174.9174.4-166.400110.6C251 E252 L253 Q257 L258 H259C251-E255 HydrophobicContact CB-CB 4.44Å; C251-E255 HydrophobicContact CB-CG 4.31Å; C251-E255 WeakPolarHBondContact CB-OE2 3.38Å; E252-E255 WeakPolarHBondContact O-CB 3.42Å; E252-E255 PolarHBondContact O-N 3.4Å; L253-E255 VanDerWaalsContact C-N 3.34Å; E255-Q257 VanDerWaalsContact C-N 3.34Å; E255-Q257 PolarHBondContact O-N 3.26Å; E255-L258 PolarHBondContact O-N 3.33Å; E255-L258 VanDerWaalsContact O-N 3.12Å; E255-H259 PolarHBondContact O-CD2 2.91Å; E255-H259 PolarHBondContact O-N 2.81Å
256A93.1Very high91.6Very high0 Ų068.4 Ų68.40%035%0.345CS..Hα-helixtrans-59.3-41.1174.600000112.7I242 L245 Q246 E252 H259 T260I242-A256 HydrophobicContact CG2-CB 4.05Å; L245-A256 HydrophobicContact CB-CB 4.19Å; Q246-A256 HydrophobicContact CG-CB 3.69Å; E252-A256 PolarHBondContact O-N 2.99Å; A256-H259 PolarHBondContact O-N 3.49Å; A256-T260 WeakPolarHBondContact O-CB 3.44Å; A256-T260 PolarHBondContact O-N 3.46Å; A256-T260 PolarHBondContact O-OG1 3.16Å
257Q93.6Very high91.4Very high89 Ų8965.4 Ų65.442%0.41633%0.331SS..Hα-helixtrans-62.7-41173.5-78.7173.4-18.200112.4I242 L253 E255 T260 T261I242-Q257 HydrophobicContact CD1-CG 3.66Å; I242-Q257 HydrophobicContact CG1-CG 4.22Å; L253-Q257 HydrophobicContact CD1-CG 4.28Å; L253-Q257 WeakPolarHBondContact O-CB 3.16Å; L253-Q257 VanDerWaalsContact O-CG 3.23Å; L253-Q257 WeakPolarHBondContact O-CG 3.46Å; L253-Q257 PolarHBondContact O-N 3.32Å; E255-Q257 VanDerWaalsContact C-N 3.34Å; E255-Q257 PolarHBondContact O-N 3.26Å; Q257-T260 PolarHBondContact O-N 3.16Å; Q257-T261 WeakPolarHBondContact O-CB 3.36Å; Q257-T261 PolarHBondContact O-N 2.92Å; Q257-T261 PolarHBondContact O-OG1 3.37Å
258L92.1Very high91.5Very high100 Ų10058.8 Ų58.852%0.52431%0.306SS..Hα-helixtrans-70.3-34.7178.5-178.4139000112.2A254 E255 A262 R269A254-L258 VanDerWaalsContact O-CB 3.27Å; A254-L258 WeakPolarHBondContact O-CB 3.26Å; A254-L258 PolarHBondContact O-N 3.01Å; E255-L258 PolarHBondContact O-N 3.33Å; E255-L258 VanDerWaalsContact O-N 3.12Å; L258-A262 WeakPolarHBondContact O-CB 3.35Å; L258-A262 PolarHBondContact O-N 2.95Å; L258-R269 PolarHBondContact O-NH1 2.99Å
259H92.5Very high91.5Very high6 Ų660.3 Ų60.33%0.02831%0.31CS..Hα-helixtrans-64-54.7168.6-78.3-69.5000111.3L245 E255 A256 T261 A262 I263 R269L245-H259 HydrophobicContact CD1-CB 3.87Å; E255-H259 PolarHBondContact O-CD2 2.91Å; E255-H259 PolarHBondContact O-N 2.81Å; A256-H259 PolarHBondContact O-N 3.49Å; H259-T261 VanDerWaalsContact C-N 3.34Å; H259-T261 PolarHBondContact O-N 2.99Å; H259-A262 PolarHBondContact O-N 3.48Å; H259-A262 VanDerWaalsContact O-N 3.07Å; H259-I263 HydrophobicContact CB-CD1 4.47Å; H259-I263 WeakPolarHBondContact O-CD1 3.26Å; H259-I263 VanDerWaalsContact O-CG1 3.3Å; H259-I263 WeakPolarHBondContact O-CG1 3.3Å; H259-I263 PolarHBondContact O-N 3.3Å; H259-R269 PolarHBondContact ND1-NE 2.68Å
260T93.5Very high91.6Very high7 Ų758.4 Ų58.44%0.04330%0.3CS..Hα-helixtrans-56.3-45.1-178-53.70000112.1Y238 V241 I242 A256 Q257 A262 I263 D264Y238-T260 HydrophobicContact CD1-CG2 3.67Å; Y238-T260 HydrophobicContact CE1-CG2 4.22Å; Y238-T260 HydrophobicContact CG-CG2 3.91Å; V241-T260 HydrophobicContact CB-CG2 3.95Å; V241-T260 HydrophobicContact CG1-CG2 3.95Å; I242-T260 HydrophobicContact CG1-CG2 4.35Å; I242-T260 WeakPolarHBondContact CG1-OG1 3.29Å; A256-T260 WeakPolarHBondContact O-CB 3.44Å; A256-T260 PolarHBondContact O-N 3.46Å; A256-T260 PolarHBondContact O-OG1 3.16Å; Q257-T260 PolarHBondContact O-N 3.16Å; T260-A262 VanDerWaalsContact C-N 3.31Å; T260-A262 PolarHBondContact O-N 2.91Å; T260-I263 PolarHBondContact O-N 2.91Å; T260-D264 PolarHBondContact O-N 3.33Å; T260-D264 VanDerWaalsContact O-N 3.13Å
261T91.9Very high91.7Very high78 Ų7851.2 Ų51.248%0.47926%0.262SS..Hα-helixtrans-63.8-34.4178.6-54.20000112.8Q257 H259 K265Q257-T261 WeakPolarHBondContact O-CB 3.36Å; Q257-T261 PolarHBondContact O-N 2.92Å; Q257-T261 PolarHBondContact O-OG1 3.37Å; H259-T261 VanDerWaalsContact C-N 3.34Å; H259-T261 PolarHBondContact O-N 2.99Å; T261-K265 WeakPolarHBondContact O-CB 3.4Å; T261-K265 PolarHBondContact O-N 3.18Å
262A89.9Confident91.8Very high14 Ų1453.3 Ų53.312%0.11627%0.269CS..Hα-helixtrans-77.6-33.4176.600000112.3L258 H259 T260 K265 E266 R269L258-A262 WeakPolarHBondContact O-CB 3.35Å; L258-A262 PolarHBondContact O-N 2.95Å; H259-A262 PolarHBondContact O-N 3.48Å; H259-A262 VanDerWaalsContact O-N 3.07Å; T260-A262 VanDerWaalsContact C-N 3.31Å; T260-A262 PolarHBondContact O-N 2.91Å; A262-K265 PolarHBondContact O-N 2.9Å; A262-E266 WeakPolarHBondContact O-CB 3.44Å; A262-E266 PolarHBondContact O-N 2.97Å; A262-R269 VanDerWaalsContact CB-NH1 3.29Å
263I92.6Very high91.8Very high4 Ų448 Ų482%0.02125%0.251CS..Hα-helixtrans-61.5-50.1175.6-69.2158.8000110.3L230 N232 H259 T260 K265 G267 R269 V271L230-I263 HydrophobicContact CB-CD1 4.14Å; L230-I263 HydrophobicContact CD2-CD1 3.56Å; L230-I263 HydrophobicContact CG-CD1 3.79Å; N232-I263 HydrophobicContact CB-CG2 3.69Å; H259-I263 HydrophobicContact CB-CD1 4.47Å; H259-I263 WeakPolarHBondContact O-CD1 3.26Å; H259-I263 VanDerWaalsContact O-CG1 3.3Å; H259-I263 WeakPolarHBondContact O-CG1 3.3Å; H259-I263 PolarHBondContact O-N 3.3Å; T260-I263 PolarHBondContact O-N 2.91Å; I263-K265 VanDerWaalsContact C-N 3.33Å; I263-K265 PolarHBondContact O-N 2.99Å; I263-G267 CarbonylContact O-C 3.55Å; I263-G267 WeakPolarHBondContact O-CA 3.39Å; I263-G267 PolarHBondContact O-N 3Å; I263-R269 HydrophobicContact CD1-CB 4.36Å; I263-R269 HydrophobicContact CG1-CB 3.56Å; I263-V271 HydrophobicContact CD1-CG1 4.48Å
264D90.4Very high91.8Very high45 Ų4545.2 Ų45.224%0.24124%0.242CC..Hα-helixtrans-57-45.7174160.657.5000112.2N232 Y238 T260 K364N232-D264 WeakPolarHBondContact OD1-CA 3.32Å; Y238-D264 VanDerWaalsContact OH-CB 3.31Å; Y238-D264 WeakPolarHBondContact OH-CB 3.4Å; Y238-D264 PolarHBondContact OH-OD2 2.83Å; T260-D264 PolarHBondContact O-N 3.33Å; T260-D264 VanDerWaalsContact O-N 3.13Å; D264-K364 VanDerWaalsContact O-CD 3.27Å; D264-K364 WeakPolarHBondContact O-CD 3.45Å; D264-K364 WeakPolarHBondContact O-CE 3.12Å; D264-K364 PolarHBondContact O-NZ 3.33Å; D264-K364 IonicContact OD1-NZ 2.93Å; D264-K364 PolarHBondContact OD1-NZ 3.29Å
265K87.1Confident91.8Very high155 Ų15544.8 Ų44.867%0.67424%0.239SC*.Hα-helixtrans-68.8-37.6-174.7-175.7-172.1171.1-154.80113.7T261 A262 I263T261-K265 WeakPolarHBondContact O-CB 3.4Å; T261-K265 PolarHBondContact O-N 3.18Å; A262-K265 PolarHBondContact O-N 2.9Å; I263-K265 VanDerWaalsContact C-N 3.33Å; I263-K265 PolarHBondContact O-N 2.99Å
266E85.7Confident91.8Very high100 Ų10043.9 Ų43.947%0.46723%0.232SC..Hα-helixtrans-108.6-17.8-170.9-62.2-179.7-165.400113A262 Y363 G365A262-E266 WeakPolarHBondContact O-CB 3.44Å; A262-E266 PolarHBondContact O-N 2.97Å; E266-Y363 WeakPolarHBondContact O-CD2 3.35Å; E266-G365 WeakPolarHBondContact O-CA 3.16Å; E266-G365 PolarHBondContact O-N 3.39Å
267G90.5Very high91.8Very high0 Ų047.4 Ų47.40%026%0.261CS..SBendtrans91.9-13.1-177.600000114.8N232 I263N232-G267 PolarHBondContact N-O 3.29Å; I263-G267 CarbonylContact O-C 3.55Å; I263-G267 WeakPolarHBondContact O-CA 3.39Å; I263-G267 PolarHBondContact O-N 3Å
268R92.5Very high91.8Very high19 Ų1944.8 Ų44.87%0.07226%0.255CS..EExtended strand (participates in β ladder)trans-166.5159.6175.466-175.7-170.8165.83.1111.7V229 L230 F231 Q311 Y363V229-R268 HydrophobicContact CG1-CB 4.07Å; V229-R268 HydrophobicContact CG1-CG 4.41Å; L230-R268 CarbonylContact O-C 3.58Å; L230-R268 VanDerWaalsContact O-CA 3.28Å; L230-R268 WeakPolarHBondContact O-CA 3.4Å; F231-R268 HydrophobicContact CB-CB 4.5Å; F231-R268 HydrophobicContact CD1-CB 3.66Å; F231-R268 HydrophobicContact CD1-CG 4.47Å; F231-R268 HydrophobicContact CE1-CB 4Å; F231-R268 VanDerWaalsContact CE1-CD 3.48Å; F231-R268 HydrophobicContact CE1-CG 4.38Å; F231-R268 HydrophobicContact CG-CB 4Å; R268-Q311 VanDerWaalsContact CZ-OE1 3.27Å; R268-Y363 HydrophobicContact CG-CD2 3.94Å; R268-Y363 HydrophobicContact CG-CE2 4.18Å; R268-Y363 HydrophobicContact CG-CG 4.19Å; R268-Y363 VanDerWaalsContact CZ-CE1 3.43Å; R268-Y363 VanDerWaalsContact NE-CZ 3.32Å; R268-Y363 PolarHBondContact NH2-OH 3.36Å
269R92.8Very high91.9Very high44 Ų4440 Ų4017%0.16623%0.23CC..EExtended strand (participates in β ladder)trans-152144.9172.1-174.4160.4177.5176.94.6112.7V229 L230 L258 H259 A262 I263 V271V229-R269 WeakPolarHBondContact CA-O 3.33Å; L230-R269 PolarHBondContact N-O 3.05Å; L230-R269 PolarHBondContact O-N 3.2Å; L258-R269 PolarHBondContact O-NH1 2.99Å; H259-R269 PolarHBondContact ND1-NE 2.68Å; A262-R269 VanDerWaalsContact CB-NH1 3.29Å; I263-R269 HydrophobicContact CD1-CB 4.36Å; I263-R269 HydrophobicContact CG1-CB 3.56Å; R269-V271 PolarHBondContact O-N 3.13Å
270A93.3Very high92.1Very high1 Ų142 Ų421%0.00824%0.239CC..EExtended strand (participates in β ladder)trans-68.3125164.800000110.2M55 Y227 C228 M308M55-A270 HydrophobicContact SD-CB 3.86Å; M55-A270 VanDerWaalsContact SD-O 3.41Å; Y227-A270 HydrophobicContact CD1-CB 3.92Å; Y227-A270 HydrophobicContact CG-CB 4.12Å; C228-A270 WeakPolarHBondContact O-CA 3.32Å; A270-M308 HydrophobicContact CB-CE 3.87Å; A270-M308 HydrophobicContact CB-SD 4.12Å
271V93.5Very high92.1Very high8 Ų847.1 Ų47.15%0.04826%0.263CS..EExtended strand (participates in β ladder)trans-113.1-15.9-179-60.50000112.9C228 L230 L245 L249 I263 R269 I286C228-V271 HydrophobicContact CB-CG2 4.41Å; C228-V271 WeakPolarHBondContact O-CG2 3.33Å; C228-V271 PolarHBondContact O-N 3.43Å; L230-V271 HydrophobicContact CB-CG1 4Å; L230-V271 HydrophobicContact CB-CG2 4.35Å; L245-V271 HydrophobicContact CD2-CB 4.21Å; L245-V271 HydrophobicContact CD2-CG1 4.01Å; L245-V271 HydrophobicContact CD2-CG2 4.37Å; L249-V271 HydrophobicContact CD1-CB 3.87Å; L249-V271 HydrophobicContact CD1-CG2 4.16Å; I263-V271 HydrophobicContact CD1-CG1 4.48Å; R269-V271 PolarHBondContact O-N 3.13Å; V271-I286 HydrophobicContact CG2-CD1 3.84Å
272K92.8Very high92.3Very high60 Ų6043.4 Ų43.426%0.26124%0.24SC..EExtended strand (participates in β ladder)trans-147.1147.6170-164.1177.2-176.3-176.40109.5Y227 C228 L249 A278 A282Y227-K272 CarbonylContact C-O 3.42Å; Y227-K272 WeakPolarHBondContact CA-O 3.29Å; C228-K272 HydrophobicContact CB-CB 3.9Å; C228-K272 PolarHBondContact N-O 3.03Å; C228-K272 PolarHBondContact O-N 2.86Å; L249-K272 HydrophobicContact CD2-CB 4.25Å; L249-K272 HydrophobicContact CD2-CD 4.18Å; K272-A278 WeakPolarHBondContact CD-O 3.36Å; K272-A278 VanDerWaalsContact CE-O 3.31Å; K272-A278 WeakPolarHBondContact CE-O 3.38Å; K272-A278 PolarHBondContact NZ-O 2.83Å; K272-A282 HydrophobicContact CB-CB 4.48Å; K272-A282 HydrophobicContact CD-CB 3.39Å
273A92.7Very high92.5Very high39 Ų3943.8 Ų43.832%0.32224%0.239SC..EExtended strand (participates in β ladder)trans-128.2140.4174.500000110.5M55 Y226 Y227M55-A273 HydrophobicContact CG-CB 3.76Å; M55-A273 HydrophobicContact SD-CB 4.4Å; Y226-A273 WeakPolarHBondContact O-CA 3.26Å; Y227-A273 HydrophobicContact CD1-CB 3.54Å; Y227-A273 HydrophobicContact CE1-CB 3.51Å
274G92.8Very high92.7Very high25 Ų2548.1 Ų48.126%0.25826%0.259SS..EExtended strand (participates in β ladder)trans166.3-157.8178.200000113.7Y226Y226-G274 PolarHBondContact N-O 3.33Å; Y226-G274 PolarHBondContact O-N 3.1Å
275A93.2Very high92.8Very high53 Ų5348.9 Ų48.944%0.43826%0.263SS..SBendtrans-68.5156.3170.300000111.1A277 A278 C279A275-A277 VanDerWaalsContact C-N 3.31Å; A275-A277 PolarHBondContact O-N 3.34Å; A275-A278 PolarHBondContact O-N 3.4Å; A275-A278 VanDerWaalsContact O-N 3.11Å; A275-C279 PolarHBondContact O-N 3.24Å
276Y92.2Very high93.2Very high75 Ų7541.5 Ų41.529%0.29423%0.231SC..Hα-helixtrans-49.7-48-177.1-177.2-105.4000113K211 Y226 A278 C279 Q280 V302K211-Y276 VanDerWaalsContact CE-CE2 3.46Å; K211-Y276 WeakPolarHBondContact CE-OH 3.4Å; K211-Y276 PolarHBondContact NZ-OH 2.76Å; Y226-Y276 AromaticContact CD1-CD2 3.76Å; Y226-Y276 HydrophobicContact CD1-CD2 3.76Å; Y226-Y276 HydrophobicContact CD2-CD2 4.49Å; Y226-Y276 AromaticContact CE1-CD2 3.77Å; Y226-Y276 HydrophobicContact CE1-CD2 3.77Å; Y226-Y276 HydrophobicContact CG-CD2 4.13Å; Y276-A278 PolarHBondContact O-N 2.99Å; Y276-C279 PolarHBondContact O-N 3.42Å; Y276-Q280 WeakPolarHBondContact O-CB 3.41Å; Y276-Q280 PolarHBondContact O-N 3.32Å; Y276-Q280 PolarHBondContact OH-OE1 3.05Å; Y276-V302 HydrophobicContact CD2-CG1 3.69Å; Y276-V302 HydrophobicContact CE2-CB 4.28Å; Y276-V302 HydrophobicContact CE2-CG1 3.75Å
277A93.4Very high93.5Very high74 Ų7439.4 Ų39.461%0.61222%0.22SC*.Hα-helixtrans-59.6-42.5-178.700000113.3A275 C279 Q280 E281A275-A277 VanDerWaalsContact C-N 3.31Å; A275-A277 PolarHBondContact O-N 3.34Å; A277-C279 VanDerWaalsContact C-N 3.33Å; A277-C279 PolarHBondContact O-N 3.01Å; A277-Q280 PolarHBondContact O-N 3.27Å; A277-E281 WeakPolarHBondContact O-CB 3.39Å; A277-E281 PolarHBondContact O-N 3.5Å
278A93.3Very high93.6Very high34 Ų3442.2 Ų42.228%0.28124%0.24SC..Hα-helixtrans-73.1-25.5-179.500000113K272 A275 Y276K272-A278 WeakPolarHBondContact CD-O 3.36Å; K272-A278 VanDerWaalsContact CE-O 3.31Å; K272-A278 WeakPolarHBondContact CE-O 3.38Å; K272-A278 PolarHBondContact NZ-O 2.83Å; A275-A278 PolarHBondContact O-N 3.4Å; A275-A278 VanDerWaalsContact O-N 3.11Å; Y276-A278 PolarHBondContact O-N 2.99Å
279C94.3Very high93.4Very high0 Ų043.7 Ų43.70%025%0.247CC..Hα-helixtrans-79.2-39.1172.5-610000111.3Y226 C228 A275 Y276 A277 A282 K283 V302Y226-C279 PolarHBondContact O-SG 3.09Å; C228-C279 HydrophobicContact CB-CB 4.15Å; A275-C279 PolarHBondContact O-N 3.24Å; Y276-C279 PolarHBondContact O-N 3.42Å; A277-C279 VanDerWaalsContact C-N 3.33Å; A277-C279 PolarHBondContact O-N 3.01Å; C279-A282 PolarHBondContact O-N 3.39Å; C279-K283 PolarHBondContact O-N 3.34Å; C279-V302 HydrophobicContact CB-CG1 3.68Å; C279-V302 HydrophobicContact CB-CG2 4.05Å
280Q95.1Very high93.2Very high46 Ų4641.6 Ų41.622%0.21524%0.24CC..Hα-helixtrans-63.2-44.1174.5-168.87040.800111.7Y276 A277 A282 K283 E284Y276-Q280 WeakPolarHBondContact O-CB 3.41Å; Y276-Q280 PolarHBondContact O-N 3.32Å; Y276-Q280 PolarHBondContact OH-OE1 3.05Å; A277-Q280 PolarHBondContact O-N 3.27Å; Q280-A282 VanDerWaalsContact C-N 3.34Å; Q280-A282 PolarHBondContact O-N 3.49Å; Q280-K283 WeakPolarHBondContact O-CB 3.48Å; Q280-K283 PolarHBondContact O-N 3.22Å; Q280-K283 VanDerWaalsContact O-N 3.08Å; Q280-E284 PolarHBondContact NE2-OE1 2.98Å; Q280-E284 PolarHBondContact O-N 3.18Å
281E95.3Very high92.9Very high116 Ų11647 Ų4754%0.54227%0.265SS..Hα-helixtrans-52.1-51.4173.1-178.6179.1-134.600111A277 K283 E284 D285A277-E281 WeakPolarHBondContact O-CB 3.39Å; A277-E281 PolarHBondContact O-N 3.5Å; E281-K283 VanDerWaalsContact C-N 3.33Å; E281-K283 PolarHBondContact O-N 3.47Å; E281-E284 PolarHBondContact O-N 3.3Å; E281-D285 PolarHBondContact O-N 3.07Å
282A94.5Very high92.2Very high0 Ų052.4 Ų52.40%029%0.293CS..Hα-helixtrans-64.8-31.9176.900000114L249 K272 C279 Q280 I286L249-A282 HydrophobicContact CD2-CB 4.04Å; K272-A282 HydrophobicContact CB-CB 4.48Å; K272-A282 HydrophobicContact CD-CB 3.39Å; C279-A282 PolarHBondContact O-N 3.39Å; Q280-A282 VanDerWaalsContact C-N 3.34Å; Q280-A282 PolarHBondContact O-N 3.49Å; A282-I286 WeakPolarHBondContact O-CB 3.47Å; A282-I286 WeakPolarHBondContact O-CD1 3.37Å; A282-I286 WeakPolarHBondContact O-CG1 3.25Å; A282-I286 PolarHBondContact O-N 2.85Å
283K95.3Very high91.4Very high22 Ų2252.3 Ų52.310%0.09630%0.298CS..Hα-helixtrans-63.5-45.4173.6167168.7170.4166.60111E210 C279 Q280 E281 K287 V300 V302E210-K283 IonicContact OE1-NZ 2.8Å; E210-K283 PolarHBondContact OE1-NZ 2.79Å; C279-K283 PolarHBondContact O-N 3.34Å; Q280-K283 WeakPolarHBondContact O-CB 3.48Å; Q280-K283 PolarHBondContact O-N 3.22Å; Q280-K283 VanDerWaalsContact O-N 3.08Å; E281-K283 VanDerWaalsContact C-N 3.33Å; E281-K283 PolarHBondContact O-N 3.47Å; K283-K287 VanDerWaalsContact O-CG 3.31Å; K283-K287 WeakPolarHBondContact O-CG 3.4Å; K283-K287 PolarHBondContact O-N 3.04Å; K283-V300 HydrophobicContact CB-CG1 3.88Å; K283-V300 HydrophobicContact CD-CG1 4.46Å; K283-V300 WeakPolarHBondContact CD-O 3.37Å; K283-V300 WeakPolarHBondContact CE-O 3.11Å; K283-V300 HydrophobicContact CG-CB 4.17Å; K283-V300 HydrophobicContact CG-CG1 3.93Å; K283-V300 PolarHBondContact NZ-O 3.27Å; K283-V302 HydrophobicContact CB-CG2 4.01Å; K283-V302 HydrophobicContact CD-CG2 3.74Å
284E95.8Very high90.8Very high94 Ų9451.9 Ų51.944%0.43929%0.293SS..Hα-helixtrans-69.2-38.8176.4-56.4-46.2140.700112Q280 E281 K287 S288Q280-E284 PolarHBondContact NE2-OE1 2.98Å; Q280-E284 PolarHBondContact O-N 3.18Å; E281-E284 PolarHBondContact O-N 3.3Å; E284-K287 PolarHBondContact O-N 2.75Å; E284-S288 VanDerWaalsContact O-CB 3.31Å; E284-S288 WeakPolarHBondContact O-CB 3.42Å; E284-S288 PolarHBondContact O-N 2.86Å
285D93.7Very high90Very high61 Ų6159.5 Ų59.533%0.32632%0.321SS..Hα-helixtrans-64.1-45177.2-73.5-33.3000112.2A248 E281 K287 S288 H289A248-D285 HydrophobicContact CB-CB 3.75Å; E281-D285 PolarHBondContact O-N 3.07Å; D285-K287 VanDerWaalsContact C-N 3.34Å; D285-K287 PolarHBondContact O-N 3.05Å; D285-S288 PolarHBondContact O-N 3.05Å; D285-H289 WeakPolarHBondContact O-CB 3.43Å; D285-H289 PolarHBondContact O-N 3.49Å; D285-H289 PolarHBondContact O-ND1 2.6Å
286I94Very high89.5Confident0 Ų063 Ų630%033%0.328CS..Hα-helixtrans-61.2-45.8177.1-68.1164.4000109.9L245 A248 V271 A282 H289 S290 L298 V300L245-I286 HydrophobicContact CD2-CD1 4.27Å; A248-I286 HydrophobicContact CB-CB 4.24Å; A248-I286 HydrophobicContact CB-CG1 3.47Å; A248-I286 VanDerWaalsContact CB-CG1 3.47Å; V271-I286 HydrophobicContact CG2-CD1 3.84Å; A282-I286 WeakPolarHBondContact O-CB 3.47Å; A282-I286 WeakPolarHBondContact O-CD1 3.37Å; A282-I286 WeakPolarHBondContact O-CG1 3.25Å; A282-I286 PolarHBondContact O-N 2.85Å; I286-H289 PolarHBondContact O-N 3.35Å; I286-S290 WeakPolarHBondContact O-CB 3.39Å; I286-S290 PolarHBondContact O-N 2.86Å; I286-S290 PolarHBondContact O-OG 3.04Å; I286-L298 HydrophobicContact CG2-CB 4.24Å; I286-L298 HydrophobicContact CG2-CD1 3.91Å; I286-V300 HydrophobicContact CB-CG2 4.21Å; I286-V300 HydrophobicContact CD1-CG1 4.47Å; I286-V300 HydrophobicContact CG2-CG2 3.69Å
287K92.8Very high89.3Confident56 Ų5662 Ų6224%0.24333%0.331CS..Hα-helixtrans-59.2-54.3177.9-74.6-176173.6-166.40111.8K283 E284 D285 H289 S290 E291 P297K283-K287 VanDerWaalsContact O-CG 3.31Å; K283-K287 WeakPolarHBondContact O-CG 3.4Å; K283-K287 PolarHBondContact O-N 3.04Å; E284-K287 PolarHBondContact O-N 2.75Å; D285-K287 VanDerWaalsContact C-N 3.34Å; D285-K287 PolarHBondContact O-N 3.05Å; K287-H289 VanDerWaalsContact C-N 3.31Å; K287-H289 PolarHBondContact O-N 3.17Å; K287-S290 WeakPolarHBondContact CA-OG 3.37Å; K287-S290 PolarHBondContact O-N 3.36Å; K287-S290 PolarHBondContact O-OG 2.95Å; K287-E291 WeakPolarHBondContact O-CG 3.41Å; K287-E291 PolarHBondContact O-N 3.12Å; K287-P297 HydrophobicContact CB-CB 4.11Å; K287-P297 HydrophobicContact CG-CB 4.06Å
288S91.6Very high89.3Confident59 Ų5958.6 Ų58.641%0.41330%0.302SS..Hα-helixtrans-55.6-43.2178.8-178.90000112.2E284 D285 N292E284-S288 VanDerWaalsContact O-CB 3.31Å; E284-S288 WeakPolarHBondContact O-CB 3.42Å; E284-S288 PolarHBondContact O-N 2.86Å; D285-S288 PolarHBondContact O-N 3.05Å; S288-N292 PolarHBondContact O-N 3.3Å; S288-N292 PolarHBondContact O-ND2 2.8Å
289H89.2Confident89.2Confident50 Ų5061.1 Ų61.123%0.23131%0.308CS..Hα-helixtrans-69.4-33.7177-7296.5000113.3R247 D285 I286 K287 N292R247-H289 HydrophobicContact CB-CB 4.39Å; R247-H289 VanDerWaalsContact CB-CD2 3.43Å; R247-H289 WeakPolarHBondContact CB-CD2 3.28Å; D285-H289 WeakPolarHBondContact O-CB 3.43Å; D285-H289 PolarHBondContact O-N 3.49Å; D285-H289 PolarHBondContact O-ND1 2.6Å; I286-H289 PolarHBondContact O-N 3.35Å; K287-H289 VanDerWaalsContact C-N 3.31Å; K287-H289 PolarHBondContact O-N 3.17Å; H289-N292 PolarHBondContact O-N 3.25Å
290S88.3Confident89.2Confident1 Ų161.1 Ų61.11%0.00731%0.308CS..Hα-helixtrans-70.8-37176.261.20000113.9I286 K287 N292 V293 S294 P297 L298I286-S290 WeakPolarHBondContact O-CB 3.39Å; I286-S290 PolarHBondContact O-N 2.86Å; I286-S290 PolarHBondContact O-OG 3.04Å; K287-S290 WeakPolarHBondContact CA-OG 3.37Å; K287-S290 PolarHBondContact O-N 3.36Å; K287-S290 PolarHBondContact O-OG 2.95Å; S290-N292 PolarHBondContact O-N 2.79Å; S290-V293 PolarHBondContact O-N 3.33Å; S290-V293 VanDerWaalsContact O-N 3.07Å; S290-S294 PolarHBondContact O-N 3.29Å; S290-S294 PolarHBondContact O-OG 2.9Å; S290-P297 WeakPolarHBondContact OG-CA 3.23Å; S290-L298 PolarHBondContact OG-N 2.73Å
291E86.4Confident89.2Confident113 Ų11361.6 Ų61.653%0.52831%0.31SS..Hα-helixtrans-65.3-24.7175.1-69.7177.7172.900112.9K287 V293 S294 P297K287-E291 WeakPolarHBondContact O-CG 3.41Å; K287-E291 PolarHBondContact O-N 3.12Å; E291-V293 PolarHBondContact O-N 3.1Å; E291-S294 VanDerWaalsContact O-O 3.13Å; E291-P297 HydrophobicContact CG-CB 3.84Å; E291-P297 HydrophobicContact CG-CG 4.36Å
292N79Confident89.2Confident122 Ų12256 Ų5665%0.65229%0.285SS*.THydrogen-bonded Turntrans-73.5-14.2174.4-74-58.7000113.5S288 H289 S290S288-N292 PolarHBondContact O-N 3.3Å; S288-N292 PolarHBondContact O-ND2 2.8Å; H289-N292 PolarHBondContact O-N 3.25Å; S290-N292 PolarHBondContact O-N 2.79Å
293V77.6Confident89.2Confident59 Ų5956.3 Ų56.336%0.35829%0.286SS..THydrogen-bonded Turntrans-117.8-21.5-174.4-174.60000112.2H240 Y243 S290 E291H240-V293 HydrophobicContact CB-CG1 4.36Å; Y243-V293 HydrophobicContact CD1-CG2 3.69Å; Y243-V293 HydrophobicContact CE1-CG2 3.63Å; S290-V293 PolarHBondContact O-N 3.33Å; S290-V293 VanDerWaalsContact O-N 3.07Å; E291-V293 PolarHBondContact O-N 3.1Å
294S79.6Confident89Confident30 Ų3055.5 Ų55.521%0.2128%0.283CS..SBendtrans-144.5167.9-171.270.30000112.1H236 S290 E291 H296H236-S294 PolarHBondContact NE2-OG 2.86Å; H236-S294 VanDerWaalsContact NE2-OG 3.08Å; S290-S294 PolarHBondContact O-N 3.29Å; S290-S294 PolarHBondContact O-OG 2.9Å; E291-S294 VanDerWaalsContact O-O 3.13Å; S294-H296 VanDerWaalsContact C-N 3.34Å; S294-H296 PolarHBondContact OG-O 3.03Å
295Q75.7Confident88.8Confident184 Ų18451.7 Ų51.786%0.8627%0.266SS*.SBendtrans-78.4-13.9-177.7-70.5-176.1-9.800114.6
296H81.6Confident88.7Confident127 Ų12749.8 Ų49.859%0.58826%0.255SS*.SBendtrans-137.4138.5-175.5-58.6101.3000109.5H236 S294H236-H296 PolarHBondContact CE1-O 3Å; H236-H296 PolarHBondContact NE2-O 3.44Å; S294-H296 VanDerWaalsContact C-N 3.34Å; S294-H296 PolarHBondContact OG-O 3.03Å
297P89.6Confident88.6Confident53 Ų5349.8 Ų49.834%0.34426%0.255SS..  trans-66.9149.2176.426-33.2000112K287 S290 E291K287-P297 HydrophobicContact CB-CB 4.11Å; K287-P297 HydrophobicContact CG-CB 4.06Å; S290-P297 WeakPolarHBondContact OG-CA 3.23Å; E291-P297 HydrophobicContact CG-CB 3.84Å; E291-P297 HydrophobicContact CG-CG 4.36Å
298L91.6Very high88.5Confident3 Ų347.7 Ų47.72%0.01625%0.246CC..  trans-58.1142.7169.2-74.8168.4000111.5L230 H236 V241 I286 S290 V300L230-L298 HydrophobicContact CD1-CB 3.86Å; L230-L298 HydrophobicContact CD1-CD1 4.27Å; L230-L298 HydrophobicContact CD1-CD2 4.33Å; L230-L298 HydrophobicContact CD1-CG 4.39Å; H236-L298 HydrophobicContact CB-CD2 4.03Å; H236-L298 WeakPolarHBondContact ND1-CD2 3.34Å; V241-L298 HydrophobicContact CG2-CD2 4.06Å; I286-L298 HydrophobicContact CG2-CB 4.24Å; I286-L298 HydrophobicContact CG2-CD1 3.91Å; S290-L298 PolarHBondContact OG-N 2.73Å; L298-V300 HydrophobicContact CB-CG2 4.34Å; L298-V300 PolarHBondContact O-N 3.2Å
299H92.1Very high88.6Confident87 Ų8744.9 Ų44.940%0.40323%0.227SC..  trans-77.8109177.8-177.745.5000111.6F231 E301F231-H299 HydrophobicContact CB-CB 4.36Å; F231-H299 AromaticContact CD2-CD2 3.81Å; F231-H299 AromaticContact CD2-NE2 3.97Å; F231-H299 AromaticContact CG-CD2 3.6Å; F231-H299 PolarHBondContact N-O 3.35Å; H299-E301 IonicContact CE1-OE1 3.71Å; H299-E301 PolarHBondContact CE1-OE1 3.39Å; H299-E301 VanDerWaalsContact CE1-OE1 3.32Å; H299-E301 IonicContact NE2-OE1 2.84Å
300V94.4Very high88.8Confident1 Ų142.5 Ų42.51%0.00622%0.216CC..EExtended strand (participates in β ladder)trans-133133.5-175.5-174.10000111.4C228 V229 L230 K283 I286 L298C228-V300 WeakPolarHBondContact SG-CG1 3.39Å; V229-V300 WeakPolarHBondContact O-CA 3.47Å; L230-V300 HydrophobicContact CB-CG2 4.47Å; L230-V300 HydrophobicContact CD1-CG2 3.66Å; K283-V300 HydrophobicContact CB-CG1 3.88Å; K283-V300 HydrophobicContact CD-CG1 4.46Å; K283-V300 WeakPolarHBondContact CD-O 3.37Å; K283-V300 WeakPolarHBondContact CE-O 3.11Å; K283-V300 HydrophobicContact CG-CB 4.17Å; K283-V300 HydrophobicContact CG-CG1 3.93Å; K283-V300 PolarHBondContact NZ-O 3.27Å; I286-V300 HydrophobicContact CB-CG2 4.21Å; I286-V300 HydrophobicContact CD1-CG1 4.47Å; I286-V300 HydrophobicContact CG2-CG2 3.69Å; L298-V300 HydrophobicContact CB-CG2 4.34Å; L298-V300 PolarHBondContact O-N 3.2Å
301E94.9Very high89Confident55 Ų5543.2 Ų43.226%0.25722%0.219SC..EExtended strand (participates in β ladder)trans-126.4162.7179.9-54.9-169.6146.300112.6V229 F231 H299 L303V229-E301 PolarHBondContact N-O 3.1Å; V229-E301 PolarHBondContact O-N 3.46Å; F231-E301 HydrophobicContact CD2-CG 4.39Å; F231-E301 HydrophobicContact CE2-CB 3.93Å; F231-E301 HydrophobicContact CE2-CG 3.76Å; F231-E301 HydrophobicContact CZ-CG 4.46Å; F231-E301 WeakPolarHBondContact CZ-OE2 3.34Å; H299-E301 IonicContact CE1-OE1 3.71Å; H299-E301 PolarHBondContact CE1-OE1 3.39Å; H299-E301 VanDerWaalsContact CE1-OE1 3.32Å; H299-E301 IonicContact NE2-OE1 2.84Å; E301-L303 HydrophobicContact CB-CD2 4.3Å; E301-L303 HydrophobicContact CB-CG 4.46Å
302V95.3Very high89.3Confident0 Ų039.9 Ų39.90%020%0.203CC..EExtended strand (participates in β ladder)trans-120.896.2176.7176.60000108.8Y226 Y227 Y276 C279 K283Y226-V302 HydrophobicContact CD1-CG1 4.14Å; Y226-V302 HydrophobicContact CG-CG1 4.37Å; Y227-V302 CarbonylContact O-C 3.59Å; Y227-V302 WeakPolarHBondContact O-CA 3.45Å; Y276-V302 HydrophobicContact CD2-CG1 3.69Å; Y276-V302 HydrophobicContact CE2-CB 4.28Å; Y276-V302 HydrophobicContact CE2-CG1 3.75Å; C279-V302 HydrophobicContact CB-CG1 3.68Å; C279-V302 HydrophobicContact CB-CG2 4.05Å; K283-V302 HydrophobicContact CB-CG2 4.01Å; K283-V302 HydrophobicContact CD-CG2 3.74Å
303L93.8Very high90.1Very high6 Ų634.1 Ų34.13%0.03117%0.172CC..EExtended strand (participates in β ladder)trans-97141.2-174.2-57.3-177.7000111.3E210 Y226 Y227 V229 E301E210-L303 HydrophobicContact CB-CD2 4.19Å; E210-L303 HydrophobicContact CG-CD2 4.03Å; Y226-L303 CarbonylContact C-O 3.6Å; Y226-L303 WeakPolarHBondContact CA-O 3.42Å; Y227-L303 PolarHBondContact N-O 3.25Å; Y227-L303 PolarHBondContact O-N 3.18Å; V229-L303 HydrophobicContact CG2-CB 4.46Å; V229-L303 HydrophobicContact CG2-CD1 4.17Å; V229-L303 HydrophobicContact CG2-CG 4.31Å; E301-L303 HydrophobicContact CB-CD2 4.3Å; E301-L303 HydrophobicContact CB-CG 4.46Å
304H92.8Very high90.9Very high5 Ų531.3 Ų31.32%0.02316%0.155CC..EExtended strand (participates in β ladder)trans-62.7140.5169-170.2-100.8000110.9E210 N223 Y226 E306 I307 M308E210-H304 PolarHBondContact O-N 3.24Å; N223-H304 PolarHBondContact O-NE2 2.85Å; Y226-H304 HydrophobicContact CD1-CB 4.31Å; Y226-H304 HydrophobicContact CE1-CB 4.14Å; Y226-H304 AromaticContact CE1-CD2 3.87Å; Y226-H304 AromaticContact CZ-CD2 3.8Å; H304-E306 VanDerWaalsContact C-N 3.29Å; H304-E306 IonicContact CE1-OE2 2.86Å; H304-E306 PolarHBondContact CE1-OE2 3.03Å; H304-E306 PolarHBondContact ND1-N 2.76Å; H304-E306 IonicContact ND1-OE2 3.22Å; H304-E306 PolarHBondContact O-N 2.83Å; H304-I307 HydrophobicContact CB-CB 4.5Å; H304-I307 HydrophobicContact CB-CD1 3.82Å; H304-I307 HydrophobicContact CB-CG1 4.02Å; H304-I307 PolarHBondContact O-N 2.89Å; H304-M308 PolarHBondContact O-N 3.34Å
305S91.4Very high91.6Very high13 Ų1330.9 Ų30.99%0.09115%0.151CC..Hα-helixtrans-57.1-39.7-172.559.90000113.7N223 R225 M308 A309N223-S305 PolarHBondContact ND2-OG 3.23Å; N223-S305 PolarHBondContact OD1-OG 3.4Å; N223-S305 VanDerWaalsContact OD1-OG 3.04Å; R225-S305 WeakPolarHBondContact O-CB 3.45Å; R225-S305 PolarHBondContact O-N 2.65Å; R225-S305 PolarHBondContact O-OG 3.4Å; R225-S305 VanDerWaalsContact O-OG 3.08Å; S305-M308 PolarHBondContact O-N 3.15Å; S305-A309 PolarHBondContact O-N 3.07Å; S305-A309 VanDerWaalsContact O-N 3.08Å
306E91Very high92.5Very high22 Ų2226 Ų2610%0.10312%0.124CC..Hα-helixtrans-70.3-31.3-180-54.8-179.6160.600112.2P48 L213 N223 H304 A309 H310P48-E306 HydrophobicContact CB-CG 4.14Å; P48-E306 HydrophobicContact CG-CB 4.31Å; P48-E306 HydrophobicContact CG-CG 4.23Å; L213-E306 HydrophobicContact CD1-CB 3.84Å; N223-E306 WeakPolarHBondContact ND2-CG 3.49Å; N223-E306 PolarHBondContact ND2-OE1 3.3Å; H304-E306 VanDerWaalsContact C-N 3.29Å; H304-E306 IonicContact CE1-OE2 2.86Å; H304-E306 PolarHBondContact CE1-OE2 3.03Å; H304-E306 PolarHBondContact ND1-N 2.76Å; H304-E306 IonicContact ND1-OE2 3.22Å; H304-E306 PolarHBondContact O-N 2.83Å; E306-A309 WeakPolarHBondContact O-CB 3.33Å; E306-A309 PolarHBondContact O-N 3.3Å; E306-H310 PolarHBondContact O-CD2 3.18Å; E306-H310 PolarHBondContact O-N 3.2Å
307I92.2Very high93.2Very high0 Ų020 Ų200%010%0.096CC..Hα-helixtrans-69-43.8177.1-60.1177000109.8E209 L213 H304 A309 H310 Q311E209-I307 VanDerWaalsContact O-CD1 3.25Å; E209-I307 WeakPolarHBondContact O-CD1 3.24Å; L213-I307 HydrophobicContact CD2-CB 4.46Å; L213-I307 HydrophobicContact CD2-CG1 3.79Å; L213-I307 HydrophobicContact CG-CG1 3.86Å; H304-I307 HydrophobicContact CB-CB 4.5Å; H304-I307 HydrophobicContact CB-CD1 3.82Å; H304-I307 HydrophobicContact CB-CG1 4.02Å; H304-I307 PolarHBondContact O-N 2.89Å; I307-A309 VanDerWaalsContact C-N 3.32Å; I307-A309 PolarHBondContact O-N 2.84Å; I307-H310 PolarHBondContact O-N 2.92Å; I307-Q311 HydrophobicContact CG2-CG 4.41Å; I307-Q311 WeakPolarHBondContact O-CB 3.34Å; I307-Q311 WeakPolarHBondContact O-CG 3.36Å; I307-Q311 PolarHBondContact O-N 3.38Å
308M91Very high93.4Very high11 Ų1117.5 Ų17.55%0.0548%0.08CC..Hα-helixtrans-61.5-40.5174.8-169.7169.917800111.8E54 Y227 V229 A270 H304 S305 K312E54-M308 HydrophobicContact CB-CE 4.02Å; E54-M308 HydrophobicContact CB-SD 4.21Å; E54-M308 HydrophobicContact CG-CE 4.07Å; E54-M308 HydrophobicContact CG-CG 4.25Å; E54-M308 HydrophobicContact CG-SD 4.13Å; Y227-M308 HydrophobicContact CD2-CB 4.21Å; Y227-M308 HydrophobicContact CD2-SD 3.62Å; Y227-M308 HydrophobicContact CE2-SD 4.26Å; Y227-M308 HydrophobicContact CG-SD 3.99Å; V229-M308 HydrophobicContact CG2-SD 3.93Å; A270-M308 HydrophobicContact CB-CE 3.87Å; A270-M308 HydrophobicContact CB-SD 4.12Å; H304-M308 PolarHBondContact O-N 3.34Å; S305-M308 PolarHBondContact O-N 3.15Å; M308-K312 WeakPolarHBondContact O-CB 3.34Å; M308-K312 PolarHBondContact O-N 3.4Å
309A92.3Very high93.5Very high1 Ų118.9 Ų18.91%0.0089%0.09CC..Hα-helixtrans-60.5-49.8173.200000112.5V47 S305 E306 I307 K312 F313V47-A309 HydrophobicContact CG1-CB 4.26Å; S305-A309 PolarHBondContact O-N 3.07Å; S305-A309 VanDerWaalsContact O-N 3.08Å; E306-A309 WeakPolarHBondContact O-CB 3.33Å; E306-A309 PolarHBondContact O-N 3.3Å; I307-A309 VanDerWaalsContact C-N 3.32Å; I307-A309 PolarHBondContact O-N 2.84Å; A309-K312 PolarHBondContact O-N 3.1Å; A309-F313 WeakPolarHBondContact O-CB 3.47Å; A309-F313 PolarHBondContact O-N 3.46Å
310H94.1Very high93.6Very high0 Ų015 Ų150%07%0.072CC..Hα-helixtrans-65.7-38.4179.7-82.1-76.4000113.3V47 Y200 M204 L213 E306 I307 F313 A314V47-H310 HydrophobicContact CG1-CB 4.4Å; Y200-H310 AromaticContact CE2-ND1 3.94Å; Y200-H310 AromaticContact CZ-ND1 3.82Å; Y200-H310 WeakPolarHBondContact OH-CB 3.37Å; Y200-H310 PolarHBondContact OH-ND1 3.19Å; Y200-H310 PolarHBondContact OH-O 3.3Å; Y200-H310 VanDerWaalsContact OH-O 3.12Å; M204-H310 HydrophobicContact CE-CB 3.73Å; M204-H310 HydrophobicContact CG-CB 4.33Å; M204-H310 HydrophobicContact SD-CB 4.23Å; L213-H310 HydrophobicContact CD2-CB 4.23Å; E306-H310 PolarHBondContact O-CD2 3.18Å; E306-H310 PolarHBondContact O-N 3.2Å; I307-H310 PolarHBondContact O-N 2.92Å; H310-F313 PolarHBondContact O-N 3.34Å; H310-A314 PolarHBondContact O-N 3.18Å
311Q93.4Very high93.6Very high16 Ų1615.1 Ų15.18%0.0757%0.072CC..Hα-helixtrans-64.8-42.5173.1-75.2-180-12.500112.4M204 W207 R268 I307 A314 L315M204-Q311 HydrophobicContact CE-CG 4.33Å; M204-Q311 WeakPolarHBondContact O-CG 3.49Å; W207-Q311 PolarHBondContact O-NE2 2.92Å; R268-Q311 VanDerWaalsContact CZ-OE1 3.27Å; I307-Q311 HydrophobicContact CG2-CG 4.41Å; I307-Q311 WeakPolarHBondContact O-CB 3.34Å; I307-Q311 WeakPolarHBondContact O-CG 3.36Å; I307-Q311 PolarHBondContact O-N 3.38Å; Q311-A314 PolarHBondContact O-N 3.47Å; Q311-L315 PolarHBondContact O-N 3.42Å
312K92.2Very high93.4Very high43 Ų4314.4 Ų14.419%0.1877%0.07CC..Hα-helixtrans-65-42.9175.9-175.9172.5-179.9176.80111.5Y51 E54 M308 A309 A314 L315 R316Y51-K312 HydrophobicContact CD1-CD 3.78Å; Y51-K312 HydrophobicContact CD1-CG 4.21Å; Y51-K312 HydrophobicContact CE1-CD 4.28Å; Y51-K312 HydrophobicContact CE1-CG 4.36Å; Y51-K312 HydrophobicContact CG-CD 4.43Å; E54-K312 VanDerWaalsContact OE1-CD 3.22Å; E54-K312 WeakPolarHBondContact OE1-CD 3.42Å; E54-K312 WeakPolarHBondContact OE1-CE 3.38Å; E54-K312 IonicContact OE1-NZ 3.87Å; E54-K312 PolarHBondContact OE1-NZ 3.22Å; E54-K312 VanDerWaalsContact OE2-CD 3.26Å; E54-K312 WeakPolarHBondContact OE2-CD 3.39Å; E54-K312 IonicContact OE2-NZ 3.35Å; E54-K312 PolarHBondContact OE2-NZ 3.01Å; M308-K312 WeakPolarHBondContact O-CB 3.34Å; M308-K312 PolarHBondContact O-N 3.4Å; A309-K312 PolarHBondContact O-N 3.1Å; K312-A314 VanDerWaalsContact C-N 3.34Å; K312-A314 PolarHBondContact O-N 2.9Å; K312-L315 PolarHBondContact O-N 2.8Å; K312-R316 PolarHBondContact O-N 3.01Å
313F95.2Very high93.1Very high0 Ų018 Ų180%09%0.086CC..Hα-helixtrans-63.2-38175.4178.1-112.5000112.5L43 V47 Y51 V66 I70 F71 Y200 A309 H310 L315 R316 L317L43-F313 HydrophobicContact CD1-CD1 4.41Å; L43-F313 HydrophobicContact CD1-CE1 3.79Å; L43-F313 HydrophobicContact CD2-CD1 4.29Å; L43-F313 HydrophobicContact CD2-CE1 3.44Å; L43-F313 VanDerWaalsContact CD2-CE1 3.44Å; L43-F313 HydrophobicContact CD2-CZ 3.88Å; L43-F313 HydrophobicContact CG-CE1 4.24Å; V47-F313 HydrophobicContact CG1-CB 3.62Å; V47-F313 HydrophobicContact CG1-CD1 4.34Å; V47-F313 HydrophobicContact CG1-CG 4.12Å; V47-F313 HydrophobicContact CG2-CB 4.2Å; V47-F313 HydrophobicContact CG2-CD1 3.52Å; V47-F313 HydrophobicContact CG2-CD2 4.39Å; V47-F313 HydrophobicContact CG2-CE1 4.04Å; V47-F313 HydrophobicContact CG2-CG 3.75Å; Y51-F313 HydrophobicContact CD2-CB 4.15Å; Y51-F313 HydrophobicContact CE2-CB 3.73Å; Y51-F313 AromaticContact CE2-CD2 3.9Å; Y51-F313 HydrophobicContact CE2-CD2 3.9Å; Y51-F313 HydrophobicContact CE2-CG 4.19Å; V66-F313 HydrophobicContact CG2-CD2 3.84Å; V66-F313 HydrophobicContact CG2-CE2 3.51Å; I70-F313 HydrophobicContact CD1-CE2 4Å; I70-F313 HydrophobicContact CD1-CZ 4.01Å; I70-F313 HydrophobicContact CG2-CE2 4.34Å; I70-F313 HydrophobicContact CG2-CZ 3.81Å; F71-F313 AromaticContact CE1-CE2 3.9Å; F71-F313 HydrophobicContact CE1-CE2 3.9Å; F71-F313 HydrophobicContact CE1-CZ 4.29Å; F71-F313 HydrophobicContact CZ-CE2 4.07Å; Y200-F313 AromaticContact CE1-CD1 3.72Å; Y200-F313 HydrophobicContact CE1-CD1 3.72Å; Y200-F313 AromaticContact CE1-CE1 3.97Å; Y200-F313 HydrophobicContact CE1-CE1 3.97Å; Y200-F313 AromaticContact CZ-CD1 3.91Å; A309-F313 WeakPolarHBondContact O-CB 3.47Å; A309-F313 PolarHBondContact O-N 3.46Å; H310-F313 PolarHBondContact O-N 3.34Å; F313-L315 VanDerWaalsContact C-N 3.27Å; F313-L315 PolarHBondContact O-N 3.17Å; F313-R316 PolarHBondContact O-N 3.07Å; F313-R316 VanDerWaalsContact O-N 3.1Å; F313-L317 HydrophobicContact CE1-CB 4.26Å; F313-L317 HydrophobicContact CE1-CD2 3.82Å; F313-L317 HydrophobicContact CE2-CB 4.37Å; F313-L317 HydrophobicContact CZ-CB 4.04Å; F313-L317 HydrophobicContact CZ-CD1 4.19Å; F313-L317 HydrophobicContact CZ-CD2 4.03Å; F313-L317 HydrophobicContact CZ-CG 4.33Å; F313-L317 WeakPolarHBondContact O-CB 3.41Å; F313-L317 PolarHBondContact O-N 3.44Å
314A95.6Very high92.9Very high0 Ų017.7 Ų17.70%08%0.084CC..Hα-helixtrans-56.2-40.3175.200000112.4Y200 M204 H310 Q311 K312 L317 G318Y200-A314 HydrophobicContact CE1-CB 4.13Å; M204-A314 HydrophobicContact CB-CB 3.96Å; H310-A314 PolarHBondContact O-N 3.18Å; Q311-A314 PolarHBondContact O-N 3.47Å; K312-A314 VanDerWaalsContact C-N 3.34Å; K312-A314 PolarHBondContact O-N 2.9Å; A314-L317 PolarHBondContact O-N 3.27Å; A314-G318 PolarHBondContact O-N 3.29Å
315L93.8Very high92.8Very high22 Ų2217.5 Ų17.512%0.1158%0.083CC..Hα-helixtrans-69.4-37.9175-61.5-161.9000113.2Q311 K312 F313 G318 S319 Y363 A366 I369Q311-L315 PolarHBondContact O-N 3.42Å; K312-L315 PolarHBondContact O-N 2.8Å; F313-L315 VanDerWaalsContact C-N 3.27Å; F313-L315 PolarHBondContact O-N 3.17Å; L315-G318 PolarHBondContact O-N 2.97Å; L315-S319 PolarHBondContact O-N 3.37Å; L315-S319 PolarHBondContact O-OG 3.13Å; L315-Y363 HydrophobicContact CD1-CE2 3.86Å; L315-Y363 VanDerWaalsContact CD1-OH 3.25Å; L315-Y363 WeakPolarHBondContact CD1-OH 3.38Å; L315-A366 HydrophobicContact CD1-CB 4.37Å; L315-A366 HydrophobicContact CD2-CB 3.95Å; L315-I369 HydrophobicContact CB-CG1 4.18Å; L315-I369 HydrophobicContact CD2-CB 4.23Å; L315-I369 HydrophobicContact CD2-CG1 4.17Å; L315-I369 HydrophobicContact CD2-CG2 4.5Å
316R94.5Very high92.4Very high82 Ų8219.6 Ų19.631%0.30910%0.098SC..Hα-helixtrans-66-39173.4-61.1-56.6-65.7136.4-7.3111.4E63 F71 K312 F313 S319 W320E63-R316 IonicContact OE1-CZ 3.92Å; E63-R316 IonicContact OE1-NH2 3.08Å; E63-R316 PolarHBondContact OE1-NH2 3.47Å; E63-R316 IonicContact OE2-CZ 3.31Å; E63-R316 IonicContact OE2-NE 3.2Å; E63-R316 PolarHBondContact OE2-NE 3.29Å; E63-R316 IonicContact OE2-NH2 3.88Å; E63-R316 PolarHBondContact OE2-NH2 2.99Å; F71-R316 HydrophobicContact CZ-CB 4.17Å; K312-R316 PolarHBondContact O-N 3.01Å; F313-R316 PolarHBondContact O-N 3.07Å; F313-R316 VanDerWaalsContact O-N 3.1Å; R316-S319 PolarHBondContact NH1-OG 2.78Å; R316-S319 VanDerWaalsContact O-CB 3.28Å; R316-S319 WeakPolarHBondContact O-CB 3.35Å; R316-S319 PolarHBondContact O-N 3.43Å; R316-W320 PolarHBondContact O-N 3.24Å
317L95.4Very high92.1Very high0 Ų020.4 Ų20.40%010%0.101CC..Hα-helixtrans-68.4-35.8176.1-174.260.8000112.1F39 F71 L74 V197 Y200 V201 F313 A314 W320 M321F39-L317 HydrophobicContact CZ-CD2 4.11Å; F71-L317 HydrophobicContact CD1-CD1 4.38Å; F71-L317 HydrophobicContact CE1-CB 4.47Å; F71-L317 HydrophobicContact CE1-CD1 3.85Å; L74-L317 HydrophobicContact CD1-CD1 4.2Å; V197-L317 HydrophobicContact CG1-CD1 3.95Å; V197-L317 HydrophobicContact CG1-CD2 3.85Å; V197-L317 HydrophobicContact CG1-CG 3.75Å; Y200-L317 HydrophobicContact CD1-CD2 3.73Å; Y200-L317 HydrophobicContact CE1-CD2 4.17Å; V201-L317 HydrophobicContact CG2-CB 4.11Å; V201-L317 HydrophobicContact CG2-CD2 3.86Å; V201-L317 HydrophobicContact CG2-CG 3.93Å; F313-L317 HydrophobicContact CE1-CB 4.26Å; F313-L317 HydrophobicContact CE1-CD2 3.82Å; F313-L317 HydrophobicContact CE2-CB 4.37Å; F313-L317 HydrophobicContact CZ-CB 4.04Å; F313-L317 HydrophobicContact CZ-CD1 4.19Å; F313-L317 HydrophobicContact CZ-CD2 4.03Å; F313-L317 HydrophobicContact CZ-CG 4.33Å; F313-L317 WeakPolarHBondContact O-CB 3.41Å; F313-L317 PolarHBondContact O-N 3.44Å; A314-L317 PolarHBondContact O-N 3.27Å; L317-W320 HydrophobicContact CD1-CD2 4.45Å; L317-W320 HydrophobicContact CD1-CE3 3.77Å; L317-W320 HydrophobicContact CD1-CZ3 4.28Å; L317-W320 PolarHBondContact O-N 3.31Å; L317-M321 PolarHBondContact O-N 2.91Å
318G95.1Very high91.6Very high1 Ų121 Ų211%0.0111%0.105CC..Hα-helixtrans-62.8-41167.400000112.8A314 L315 W320 M321 N322A314-G318 PolarHBondContact O-N 3.29Å; L315-G318 PolarHBondContact O-N 2.97Å; G318-W320 VanDerWaalsContact C-N 3.33Å; G318-W320 PolarHBondContact O-N 3.08Å; G318-M321 PolarHBondContact O-N 3.48Å; G318-N322 PolarHBondContact O-N 3.3Å
319S93.6Very high91.3Very high31 Ų3122 Ų2222%0.21711%0.112CC..Hα-helixtrans-61.3-41173.5-50.50000111.9L315 R316 N322 K323 I369L315-S319 PolarHBondContact O-N 3.37Å; L315-S319 PolarHBondContact O-OG 3.13Å; R316-S319 PolarHBondContact NH1-OG 2.78Å; R316-S319 VanDerWaalsContact O-CB 3.28Å; R316-S319 WeakPolarHBondContact O-CB 3.35Å; R316-S319 PolarHBondContact O-N 3.43Å; S319-N322 PolarHBondContact O-N 2.83Å; S319-K323 PolarHBondContact O-N 3Å; S319-K323 VanDerWaalsContact O-N 3.14Å; S319-I369 WeakPolarHBondContact OG-CD1 3.49Å
320W94.6Very high91Very high7 Ų722.9 Ų22.93%0.02712%0.117CC..Hα-helixtrans-64.9-43.2174.317484.4000111.8F71 L74 E75 V197 R316 L317 G318 N322 K323 I324F71-W320 HydrophobicContact CD1-CB 3.97Å; F71-W320 AromaticContact CD1-CD1 3.74Å; F71-W320 HydrophobicContact CD1-CD2 4.11Å; F71-W320 AromaticContact CD1-CG 3.67Å; F71-W320 HydrophobicContact CD1-CG 3.67Å; F71-W320 HydrophobicContact CE1-CB 3.71Å; F71-W320 AromaticContact CE1-CG 3.93Å; F71-W320 HydrophobicContact CE1-CG 3.93Å; F71-W320 HydrophobicContact CE2-CB 4.42Å; F71-W320 HydrophobicContact CG-CB 4.46Å; F71-W320 AromaticContact CG-CD1 3.69Å; F71-W320 HydrophobicContact CG-CG 4.07Å; F71-W320 HydrophobicContact CZ-CB 3.95Å; L74-W320 HydrophobicContact CB-CH2 4.03Å; L74-W320 HydrophobicContact CB-CZ2 3.89Å; L74-W320 HydrophobicContact CD1-CH2 4.26Å; L74-W320 HydrophobicContact CD1-CZ3 4.4Å; E75-W320 HydrophobicContact CG-CZ2 3.98Å; E75-W320 PolarHBondContact OE1-NE1 3.04Å; V197-W320 HydrophobicContact CG1-CZ3 4.48Å; R316-W320 PolarHBondContact O-N 3.24Å; L317-W320 HydrophobicContact CD1-CD2 4.45Å; L317-W320 HydrophobicContact CD1-CE3 3.77Å; L317-W320 HydrophobicContact CD1-CZ3 4.28Å; L317-W320 PolarHBondContact O-N 3.31Å; G318-W320 VanDerWaalsContact C-N 3.33Å; G318-W320 PolarHBondContact O-N 3.08Å; W320-N322 VanDerWaalsContact C-N 3.34Å; W320-N322 PolarHBondContact O-N 2.99Å; W320-K323 WeakPolarHBondContact O-CB 3.22Å; W320-K323 PolarHBondContact O-N 3.45Å; W320-K323 VanDerWaalsContact O-N 3.13Å; W320-I324 HydrophobicContact CD2-CG1 4.03Å; W320-I324 HydrophobicContact CE3-CG1 4.37Å; W320-I324 HydrophobicContact CH2-CG1 4.11Å; W320-I324 HydrophobicContact CZ2-CD1 3.91Å; W320-I324 HydrophobicContact CZ2-CG1 3.71Å; W320-I324 HydrophobicContact CZ3-CG1 4.42Å; W320-I324 WeakPolarHBondContact O-CG1 3.41Å; W320-I324 PolarHBondContact O-N 3.4Å
321M93.9Very high90.8Very high3 Ų322.9 Ų22.92%0.01512%0.117CC..Hα-helixtrans-60.6-42.2176.2-172.860.870.200111.8F194 V197 L317 G318 K323 I324 M325 F335 L373F194-M321 HydrophobicContact CD1-CE 4.21Å; F194-M321 HydrophobicContact CD1-SD 4.44Å; F194-M321 HydrophobicContact CD2-CE 4.43Å; F194-M321 HydrophobicContact CD2-SD 3.99Å; F194-M321 HydrophobicContact CE1-CE 4.45Å; F194-M321 HydrophobicContact CE1-SD 4.24Å; F194-M321 HydrophobicContact CE2-SD 3.77Å; F194-M321 HydrophobicContact CG-CE 4.2Å; F194-M321 HydrophobicContact CG-SD 4.32Å; F194-M321 HydrophobicContact CZ-SD 3.91Å; V197-M321 HydrophobicContact CB-CE 3.95Å; V197-M321 HydrophobicContact CG1-CE 3.43Å; V197-M321 VanDerWaalsContact CG1-CE 3.43Å; L317-M321 PolarHBondContact O-N 2.91Å; G318-M321 PolarHBondContact O-N 3.48Å; M321-K323 PolarHBondContact O-N 2.85Å; M321-I324 PolarHBondContact O-N 3.01Å; M321-M325 HydrophobicContact CG-CE 4.19Å; M321-M325 HydrophobicContact CG-CG 4.47Å; M321-M325 HydrophobicContact CG-SD 4.36Å; M321-M325 WeakPolarHBondContact O-CB 3.41Å; M321-M325 WeakPolarHBondContact O-CG 3.48Å; M321-M325 PolarHBondContact O-N 3.48Å; M321-M325 HydrophobicContact SD-CG 4.48Å; M321-F335 HydrophobicContact CG-CD2 3.67Å; M321-F335 HydrophobicContact CG-CE2 3.68Å; M321-F335 HydrophobicContact SD-CD2 4Å; M321-L373 HydrophobicContact CB-CD2 4.17Å; M321-L373 HydrophobicContact CG-CD2 4.23Å
322N90.8Very high90.7Very high39 Ų3922.9 Ų22.921%0.20912%0.116CC..Hα-helixtrans-56.5-46.7172.7-175.45.4000111.6G318 S319 W320 I324 M325 S326 E372 L373 S376G318-N322 PolarHBondContact O-N 3.3Å; S319-N322 PolarHBondContact O-N 2.83Å; W320-N322 VanDerWaalsContact C-N 3.34Å; W320-N322 PolarHBondContact O-N 2.99Å; N322-I324 PolarHBondContact O-N 3.07Å; N322-M325 PolarHBondContact O-N 3.27Å; N322-S326 PolarHBondContact O-N 2.77Å; N322-S326 VanDerWaalsContact O-N 3.11Å; N322-E372 PolarHBondContact ND2-OE2 3.48Å; N322-L373 HydrophobicContact CB-CD2 4.36Å; N322-S376 WeakPolarHBondContact OD1-CB 3.26Å; N322-S376 PolarHBondContact OD1-OG 3.39Å
323K89.3Confident90.7Very high76 Ų7622.3 Ų22.333%0.3311%0.114SC..Hα-helixtrans-56.7-47.1173.4-178.9-165.7173.3-155.60111.7E75 S319 W320 M321 S326 Y327E75-K323 IonicContact OE1-NZ 3.05Å; E75-K323 PolarHBondContact OE1-NZ 3.36Å; S319-K323 PolarHBondContact O-N 3Å; S319-K323 VanDerWaalsContact O-N 3.14Å; W320-K323 WeakPolarHBondContact O-CB 3.22Å; W320-K323 PolarHBondContact O-N 3.45Å; W320-K323 VanDerWaalsContact O-N 3.13Å; M321-K323 PolarHBondContact O-N 2.85Å; K323-S326 WeakPolarHBondContact O-CB 3.4Å; K323-S326 PolarHBondContact O-N 2.97Å; K323-S326 PolarHBondContact O-OG 3.37Å; K323-Y327 WeakPolarHBondContact CE-OH 3.35Å; K323-Y327 HydrophobicContact CG-CE2 4.14Å; K323-Y327 WeakPolarHBondContact O-CD2 3.47Å; K323-Y327 VanDerWaalsContact O-CE2 3.24Å; K323-Y327 WeakPolarHBondContact O-CE2 3.25Å
324I89.6Confident90.6Very high0 Ų022.8 Ų22.80%012%0.117CC..Hα-helixtrans-63.1-45.4178.9-62.9-62.7000111.9E75 L78 F79 F194 W320 M321 N322 S326 Y327 F331E75-I324 HydrophobicContact CG-CD1 4.3Å; L78-I324 HydrophobicContact CD2-CD1 4.2Å; L78-I324 HydrophobicContact CD2-CG2 3.91Å; F79-I324 HydrophobicContact CZ-CD1 4.26Å; F194-I324 HydrophobicContact CE1-CG2 4.34Å; F194-I324 HydrophobicContact CZ-CG2 3.81Å; W320-I324 HydrophobicContact CD2-CG1 4.03Å; W320-I324 HydrophobicContact CE3-CG1 4.37Å; W320-I324 HydrophobicContact CH2-CG1 4.11Å; W320-I324 HydrophobicContact CZ2-CD1 3.91Å; W320-I324 HydrophobicContact CZ2-CG1 3.71Å; W320-I324 HydrophobicContact CZ3-CG1 4.42Å; W320-I324 WeakPolarHBondContact O-CG1 3.41Å; W320-I324 PolarHBondContact O-N 3.4Å; M321-I324 PolarHBondContact O-N 3.01Å; N322-I324 PolarHBondContact O-N 3.07Å; I324-S326 PolarHBondContact O-N 2.9Å; I324-Y327 HydrophobicContact CD1-CE2 4.38Å; I324-Y327 WeakPolarHBondContact O-CD2 3.48Å; I324-Y327 PolarHBondContact O-N 3.29Å; I324-Y327 VanDerWaalsContact O-N 3.13Å; I324-F331 HydrophobicContact CG2-CD1 4.33Å; I324-F331 HydrophobicContact CG2-CD2 3.95Å; I324-F331 HydrophobicContact CG2-CE2 4.16Å; I324-F331 HydrophobicContact CG2-CG 4.06Å; I324-F331 HydrophobicContact CG2-CZ 4.44Å; I324-F331 WeakPolarHBondContact O-CD2 3.24Å
325M89Confident90.6Very high0 Ų023.2 Ų23.20%012%0.119CC..Hα-helixtrans-63.8-23.8179-72-170.1-57.500113.9M321 N322 Y327 R332 F335 L373 S376M321-M325 HydrophobicContact CG-CE 4.19Å; M321-M325 HydrophobicContact CG-CG 4.47Å; M321-M325 HydrophobicContact CG-SD 4.36Å; M321-M325 WeakPolarHBondContact O-CB 3.41Å; M321-M325 WeakPolarHBondContact O-CG 3.48Å; M321-M325 PolarHBondContact O-N 3.48Å; M321-M325 HydrophobicContact SD-CG 4.48Å; N322-M325 PolarHBondContact O-N 3.27Å; M325-Y327 PolarHBondContact O-N 2.93Å; M325-R332 HydrophobicContact CB-CG 3.98Å; M325-R332 HydrophobicContact CG-CG 4.44Å; M325-R332 WeakPolarHBondContact O-CG 3.28Å; M325-R332 PolarHBondContact O-NH1 3.48Å; M325-R332 VanDerWaalsContact O-NH1 3.16Å; M325-F335 HydrophobicContact CE-CD1 4.43Å; M325-F335 HydrophobicContact CE-CD2 4.35Å; M325-F335 HydrophobicContact CE-CE1 4.41Å; M325-F335 HydrophobicContact CE-CE2 4.34Å; M325-F335 HydrophobicContact CE-CG 4.41Å; M325-F335 HydrophobicContact CE-CZ 4.37Å; M325-F335 HydrophobicContact CG-CB 4.38Å; M325-F335 HydrophobicContact SD-CB 3.55Å; M325-F335 VanDerWaalsContact SD-CB 3.55Å; M325-F335 HydrophobicContact SD-CD1 3.56Å; M325-F335 VanDerWaalsContact SD-CD1 3.56Å; M325-F335 HydrophobicContact SD-CD2 3.59Å; M325-F335 VanDerWaalsContact SD-CD2 3.59Å; M325-F335 HydrophobicContact SD-CE1 4.11Å; M325-F335 HydrophobicContact SD-CE2 4.15Å; M325-F335 HydrophobicContact SD-CG 3.27Å; M325-F335 WeakPolarHBondContact SD-CG 3.49Å; M325-F335 HydrophobicContact SD-CZ 4.38Å; M325-L373 HydrophobicContact CE-CD2 3.55Å; M325-S376 WeakPolarHBondContact CE-OG 3.22Å
326S84.7Confident90.7Very high57 Ų5722.2 Ų22.240%0.39911%0.113SC..THydrogen-bonded Turntrans-65.5-21.7174.780.70000113.5F96 N322 K323 I324F96-S326 WeakPolarHBondContact CZ-O 3.3Å; N322-S326 PolarHBondContact O-N 2.77Å; N322-S326 VanDerWaalsContact O-N 3.11Å; K323-S326 WeakPolarHBondContact O-CB 3.4Å; K323-S326 PolarHBondContact O-N 2.97Å; K323-S326 PolarHBondContact O-OG 3.37Å; I324-S326 PolarHBondContact O-N 2.9Å
327Y83.2Confident90.7Very high40 Ų4022.6 Ų22.616%0.15712%0.119CC..THydrogen-bonded Turntrans-85.4-23.9-173.7-58.9-55.9000115.4L87 K323 I324 M325L87-Y327 HydrophobicContact CD1-CE2 4.48Å; L87-Y327 HydrophobicContact CD2-CD1 4.19Å; L87-Y327 HydrophobicContact CD2-CD2 3.44Å; L87-Y327 VanDerWaalsContact CD2-CD2 3.44Å; L87-Y327 HydrophobicContact CD2-CE1 4.05Å; L87-Y327 HydrophobicContact CD2-CE2 3.27Å; L87-Y327 HydrophobicContact CD2-CG 3.92Å; K323-Y327 WeakPolarHBondContact CE-OH 3.35Å; K323-Y327 HydrophobicContact CG-CE2 4.14Å; K323-Y327 WeakPolarHBondContact O-CD2 3.47Å; K323-Y327 VanDerWaalsContact O-CE2 3.24Å; K323-Y327 WeakPolarHBondContact O-CE2 3.25Å; I324-Y327 HydrophobicContact CD1-CE2 4.38Å; I324-Y327 WeakPolarHBondContact O-CD2 3.48Å; I324-Y327 PolarHBondContact O-N 3.29Å; I324-Y327 VanDerWaalsContact O-N 3.13Å; M325-Y327 PolarHBondContact O-N 2.93Å
328S83.1Confident90.6Very high12 Ų1223 Ų238%0.08412%0.122CC..  trans-156.3147.4-177.9178.20000113.2D330 F331 R332S328-D330 VanDerWaalsContact C-N 3.28Å; S328-D330 PolarHBondContact O-N 3.24Å; S328-D330 PolarHBondContact OG-N 3.3Å; S328-D330 VanDerWaalsContact OG-N 3.1Å; S328-F331 PolarHBondContact O-N 3.2Å; S328-R332 PolarHBondContact O-N 3.44Å; S328-R332 PolarHBondContact O-NH1 2.91Å
329S83.4Confident90.7Very high31 Ų3123.1 Ų23.122%0.21712%0.123CC..Hα-helixtrans-60.7-36.6168.152.30000112.4F331 R332 Q333 E381S329-F331 VanDerWaalsContact C-N 3.3Å; S329-F331 PolarHBondContact O-N 3.33Å; S329-R332 WeakPolarHBondContact O-CB 3.22Å; S329-R332 PolarHBondContact O-N 3.1Å; S329-R332 VanDerWaalsContact O-N 3.13Å; S329-Q333 WeakPolarHBondContact O-CG 3.39Å; S329-Q333 PolarHBondContact O-N 3.05Å; S329-E381 WeakPolarHBondContact CB-OE1 3.34Å
330D86.8Confident90.7Very high20 Ų2023.4 Ų23.411%0.10712%0.122CC..Hα-helixtrans-64.5-37.7-176.7-60.3-32.6000110.9P181 L182 S328 Q333 I334P181-D330 WeakPolarHBondContact CA-OD2 3.34Å; L182-D330 HydrophobicContact CB-CB 4.43Å; L182-D330 HydrophobicContact CD1-CB 3.64Å; L182-D330 HydrophobicContact CG-CB 3.87Å; L182-D330 PolarHBondContact N-OD2 3.19Å; S328-D330 VanDerWaalsContact C-N 3.28Å; S328-D330 PolarHBondContact O-N 3.24Å; S328-D330 PolarHBondContact OG-N 3.3Å; S328-D330 VanDerWaalsContact OG-N 3.1Å; D330-Q333 PolarHBondContact O-N 3.23Å; D330-I334 WeakPolarHBondContact O-CD1 3.24Å; D330-I334 VanDerWaalsContact O-CG1 3.22Å; D330-I334 WeakPolarHBondContact O-CG1 3.24Å; D330-I334 PolarHBondContact O-N 2.91Å
331F90.5Very high90.4Very high0 Ų030.9 Ų30.90%015%0.15CC..Hα-helixtrans-62.8-44172.8-71-45000112.1L78 F79 L90 L182 V186 A190 F194 I324 S328 S329 Q333 I334 F335L78-F331 HydrophobicContact CD1-CE1 4.02Å; L78-F331 HydrophobicContact CD2-CE1 4.23Å; L78-F331 HydrophobicContact CD2-CZ 4.21Å; L78-F331 HydrophobicContact CG-CE1 4.35Å; L78-F331 HydrophobicContact CG-CZ 4.47Å; F79-F331 HydrophobicContact CE1-CE2 4.34Å; F79-F331 AromaticContact CE1-CZ 3.98Å; F79-F331 HydrophobicContact CE1-CZ 3.98Å; L90-F331 HydrophobicContact CD1-CE2 4.23Å; L182-F331 HydrophobicContact CD1-CD1 3.52Å; L182-F331 HydrophobicContact CD1-CD2 4.03Å; L182-F331 HydrophobicContact CD1-CE1 3.36Å; L182-F331 HydrophobicContact CD1-CE2 3.89Å; L182-F331 HydrophobicContact CD1-CG 3.84Å; L182-F331 HydrophobicContact CD1-CZ 3.55Å; L182-F331 HydrophobicContact CD2-CE2 3.96Å; L182-F331 HydrophobicContact CD2-CZ 3.97Å; L182-F331 HydrophobicContact CG-CZ 4.44Å; V186-F331 HydrophobicContact CG1-CE1 3.93Å; V186-F331 HydrophobicContact CG1-CZ 3.81Å; A190-F331 HydrophobicContact CB-CD1 4.14Å; A190-F331 HydrophobicContact CB-CE1 4.01Å; F194-F331 HydrophobicContact CE1-CD1 4.28Å; F194-F331 HydrophobicContact CE2-CB 4.14Å; F194-F331 HydrophobicContact CE2-CD1 4.26Å; F194-F331 WeakPolarHBondContact CE2-O 3.29Å; F194-F331 HydrophobicContact CZ-CB 4.09Å; F194-F331 AromaticContact CZ-CD1 3.58Å; F194-F331 HydrophobicContact CZ-CD1 3.58Å; F194-F331 HydrophobicContact CZ-CE1 4.33Å; F194-F331 HydrophobicContact CZ-CG 4.08Å; I324-F331 HydrophobicContact CG2-CD1 4.33Å; I324-F331 HydrophobicContact CG2-CD2 3.95Å; I324-F331 HydrophobicContact CG2-CE2 4.16Å; I324-F331 HydrophobicContact CG2-CG 4.06Å; I324-F331 HydrophobicContact CG2-CZ 4.44Å; I324-F331 WeakPolarHBondContact O-CD2 3.24Å; S328-F331 PolarHBondContact O-N 3.2Å; S329-F331 VanDerWaalsContact C-N 3.3Å; S329-F331 PolarHBondContact O-N 3.33Å; F331-Q333 VanDerWaalsContact C-N 3.34Å; F331-Q333 PolarHBondContact O-N 3.04Å; F331-I334 PolarHBondContact O-N 3.02Å; F331-F335 WeakPolarHBondContact O-CB 3.4Å; F331-F335 PolarHBondContact O-N 3.28Å
332R90.6Very high89.8Confident17 Ų1736.7 Ų36.76%0.06418%0.177CC..Hα-helixtrans-59.9-44.3175.7-67.7-174-64.9-94.411.5111.9M325 S328 S329 F335 C336 S376 E381M325-R332 HydrophobicContact CB-CG 3.98Å; M325-R332 HydrophobicContact CG-CG 4.44Å; M325-R332 WeakPolarHBondContact O-CG 3.28Å; M325-R332 PolarHBondContact O-NH1 3.48Å; M325-R332 VanDerWaalsContact O-NH1 3.16Å; S328-R332 PolarHBondContact O-N 3.44Å; S328-R332 PolarHBondContact O-NH1 2.91Å; S329-R332 WeakPolarHBondContact O-CB 3.22Å; S329-R332 PolarHBondContact O-N 3.1Å; S329-R332 VanDerWaalsContact O-N 3.13Å; R332-F335 PolarHBondContact O-N 3.44Å; R332-C336 PolarHBondContact O-N 3.21Å; R332-C336 PolarHBondContact O-SG 3.22Å; R332-S376 WeakPolarHBondContact CD-O 3.29Å; R332-S376 WeakPolarHBondContact CG-O 3.14Å; R332-E381 HydrophobicContact CB-CG 4.19Å; R332-E381 IonicContact CZ-OE1 3.86Å; R332-E381 VanDerWaalsContact CZ-OE1 3.27Å; R332-E381 IonicContact NE-OE1 2.8Å; R332-E381 PolarHBondContact NE-OE1 3.25Å; R332-E381 IonicContact NH2-OE1 3.93Å; R332-E381 PolarHBondContact NH2-OE1 2.53Å
333Q91.4Very high89.2Confident31 Ų3138.9 Ų38.915%0.14519%0.186CC..Hα-helixtrans-65.5-41.5179.7-64.3-1801700111.6S329 D330 F331 C336 Q337 E381 Y384S329-Q333 WeakPolarHBondContact O-CG 3.39Å; S329-Q333 PolarHBondContact O-N 3.05Å; D330-Q333 PolarHBondContact O-N 3.23Å; F331-Q333 VanDerWaalsContact C-N 3.34Å; F331-Q333 PolarHBondContact O-N 3.04Å; Q333-C336 PolarHBondContact O-N 3.08Å; Q333-Q337 WeakPolarHBondContact O-CB 3.46Å; Q333-Q337 VanDerWaalsContact O-CG 3.22Å; Q333-Q337 WeakPolarHBondContact O-CG 3.34Å; Q333-Q337 PolarHBondContact O-N 3.09Å; Q333-E381 HydrophobicContact CG-CG 4.34Å; Q333-E381 PolarHBondContact NE2-OE2 3.48Å; Q333-Y384 HydrophobicContact CB-CE2 3.95Å; Q333-Y384 HydrophobicContact CG-CD2 4.27Å; Q333-Y384 HydrophobicContact CG-CE2 3.65Å
334I93.4Very high88.3Confident9 Ų940.5 Ų40.55%0.04620%0.204CC..Hα-helixtrans-64.1-41.3174.5-66.5164.4000111.2I187 A190 R191 F194 D330 F331 Q337 A338I187-I334 HydrophobicContact CG2-CD1 4.16Å; A190-I334 HydrophobicContact CB-CD1 3.85Å; A190-I334 HydrophobicContact CB-CG2 4.38Å; R191-I334 HydrophobicContact CG-CD1 4.31Å; R191-I334 HydrophobicContact CG-CG1 4.25Å; R191-I334 HydrophobicContact CG-CG2 4.04Å; F194-I334 HydrophobicContact CB-CG2 4.17Å; F194-I334 HydrophobicContact CD2-CB 4.36Å; F194-I334 HydrophobicContact CD2-CG2 3.89Å; F194-I334 HydrophobicContact CG-CG2 4.11Å; D330-I334 WeakPolarHBondContact O-CD1 3.24Å; D330-I334 VanDerWaalsContact O-CG1 3.22Å; D330-I334 WeakPolarHBondContact O-CG1 3.24Å; D330-I334 PolarHBondContact O-N 2.91Å; F331-I334 PolarHBondContact O-N 3.02Å; I334-Q337 PolarHBondContact O-N 3.23Å; I334-A338 WeakPolarHBondContact O-CB 3.19Å; I334-A338 PolarHBondContact O-N 2.86Å
335F95.3Very high87.3Confident10 Ų1048.9 Ų48.94%0.04425%0.249CC..Hα-helixtrans-60.9-52.3174.7176.3-88.8000111.6F194 I198 M321 M325 F331 R332 Q337 A338 C339 L373 S377 F378F194-F335 HydrophobicContact CD2-CB 3.92Å; F194-F335 HydrophobicContact CE2-CB 4.14Å; I198-F335 HydrophobicContact CD1-CD2 3.49Å; I198-F335 VanDerWaalsContact CD1-CD2 3.49Å; I198-F335 HydrophobicContact CD1-CE2 3.81Å; I198-F335 HydrophobicContact CD1-CG 4.16Å; I198-F335 HydrophobicContact CG1-CD2 3.87Å; I198-F335 HydrophobicContact CG1-CE2 3.74Å; M321-F335 HydrophobicContact CG-CD2 3.67Å; M321-F335 HydrophobicContact CG-CE2 3.68Å; M321-F335 HydrophobicContact SD-CD2 4Å; M325-F335 HydrophobicContact CE-CD1 4.43Å; M325-F335 HydrophobicContact CE-CD2 4.35Å; M325-F335 HydrophobicContact CE-CE1 4.41Å; M325-F335 HydrophobicContact CE-CE2 4.34Å; M325-F335 HydrophobicContact CE-CG 4.41Å; M325-F335 HydrophobicContact CE-CZ 4.37Å; M325-F335 HydrophobicContact CG-CB 4.38Å; M325-F335 HydrophobicContact SD-CB 3.55Å; M325-F335 VanDerWaalsContact SD-CB 3.55Å; M325-F335 HydrophobicContact SD-CD1 3.56Å; M325-F335 VanDerWaalsContact SD-CD1 3.56Å; M325-F335 HydrophobicContact SD-CD2 3.59Å; M325-F335 VanDerWaalsContact SD-CD2 3.59Å; M325-F335 HydrophobicContact SD-CE1 4.11Å; M325-F335 HydrophobicContact SD-CE2 4.15Å; M325-F335 HydrophobicContact SD-CG 3.27Å; M325-F335 WeakPolarHBondContact SD-CG 3.49Å; M325-F335 HydrophobicContact SD-CZ 4.38Å; F331-F335 WeakPolarHBondContact O-CB 3.4Å; F331-F335 PolarHBondContact O-N 3.28Å; R332-F335 PolarHBondContact O-N 3.44Å; F335-Q337 VanDerWaalsContact C-N 3.32Å; F335-Q337 PolarHBondContact O-N 2.96Å; F335-A338 PolarHBondContact O-N 3.21Å; F335-A338 VanDerWaalsContact O-N 3.12Å; F335-C339 VanDerWaalsContact CE1-SG 3.52Å; F335-C339 VanDerWaalsContact CZ-SG 3.55Å; F335-C339 WeakPolarHBondContact O-CB 3.46Å; F335-C339 PolarHBondContact O-N 2.82Å; F335-L373 HydrophobicContact CE2-CD2 4.22Å; F335-L373 HydrophobicContact CZ-CB 4.22Å; F335-L373 HydrophobicContact CZ-CD1 4.49Å; F335-L373 HydrophobicContact CZ-CD2 4.09Å; F335-S377 WeakPolarHBondContact CD1-OG 3.07Å; F335-S377 VanDerWaalsContact CE1-OG 3.3Å; F335-S377 WeakPolarHBondContact CE1-OG 3.42Å; F335-F378 HydrophobicContact CE1-CE2 4.13Å
336C95.9Very high86.6Confident0 Ų050.9 Ų50.90%026%0.263CS..Hα-helixtrans-61.3-39.4179.5-660000112.1R332 Q333 C339 L340 F378 Y384R332-C336 PolarHBondContact O-N 3.21Å; R332-C336 PolarHBondContact O-SG 3.22Å; Q333-C336 PolarHBondContact O-N 3.08Å; C336-C339 PolarHBondContact O-N 2.65Å; C336-L340 WeakPolarHBondContact O-CB 3.33Å; C336-L340 VanDerWaalsContact O-CG 3.3Å; C336-L340 WeakPolarHBondContact O-CG 3.39Å; C336-L340 PolarHBondContact O-N 3.02Å; C336-F378 HydrophobicContact CB-CD1 4.06Å; C336-F378 HydrophobicContact CB-CE1 3.75Å; C336-F378 HydrophobicContact CB-CZ 4.07Å; C336-F378 VanDerWaalsContact SG-CD1 3.6Å; C336-Y384 HydrophobicContact CB-CD1 3.25Å; C336-Y384 HydrophobicContact CB-CD2 4.4Å; C336-Y384 HydrophobicContact CB-CE1 3.79Å; C336-Y384 HydrophobicContact CB-CG 3.59Å
337Q94.8Very high86.2Confident90 Ų9057.8 Ų57.842%0.42129%0.289SS..Hα-helixtrans-61.3-42.6173.4-75.6173.66.800112.5Q333 I334 F335 R341 Y384Q333-Q337 WeakPolarHBondContact O-CB 3.46Å; Q333-Q337 VanDerWaalsContact O-CG 3.22Å; Q333-Q337 WeakPolarHBondContact O-CG 3.34Å; Q333-Q337 PolarHBondContact O-N 3.09Å; I334-Q337 PolarHBondContact O-N 3.23Å; F335-Q337 VanDerWaalsContact C-N 3.32Å; F335-Q337 PolarHBondContact O-N 2.96Å; Q337-R341 PolarHBondContact O-N 2.92Å; Q337-Y384 HydrophobicContact CG-CE1 3.95Å; Q337-Y384 PolarHBondContact NE2-OH 3.1Å
338A94.4Very high86.2Confident9 Ų960.4 Ų60.47%0.07431%0.305CS..Hα-helixtrans-68.1-39.6177.500000112.1P195 I198 I334 F335 R341P195-A338 HydrophobicContact CB-CB 4.39Å; P195-A338 HydrophobicContact CG-CB 3.96Å; I198-A338 HydrophobicContact CD1-CB 3.61Å; I334-A338 WeakPolarHBondContact O-CB 3.19Å; I334-A338 PolarHBondContact O-N 2.86Å; F335-A338 PolarHBondContact O-N 3.21Å; F335-A338 VanDerWaalsContact O-N 3.12Å; A338-R341 WeakPolarHBondContact O-CB 3.1Å; A338-R341 PolarHBondContact O-N 2.69Å
339C95.2Very high86.6Confident3 Ų361.4 Ų61.42%0.0231%0.312CS..Hα-helixtrans-66.3-35.8176.1-78.70000114.1F335 C336 R341 L351 I352 F378F335-C339 VanDerWaalsContact CE1-SG 3.52Å; F335-C339 VanDerWaalsContact CZ-SG 3.55Å; F335-C339 WeakPolarHBondContact O-CB 3.46Å; F335-C339 PolarHBondContact O-N 2.82Å; C336-C339 PolarHBondContact O-N 2.65Å; C339-R341 VanDerWaalsContact C-N 3.34Å; C339-L351 PolarHBondContact O-N 2.79Å; C339-L351 VanDerWaalsContact O-N 3.1Å; C339-I352 HydrophobicContact CB-CB 4.12Å; C339-I352 HydrophobicContact CB-CG2 4.37Å; C339-I352 PolarHBondContact O-N 2.65Å; C339-F378 HydrophobicContact CB-CE2 4.15Å; C339-F378 HydrophobicContact CB-CZ 3.72Å
340L93.7Very high87.1Confident38 Ų3860.1 Ų60.120%0.19930%0.303CS..THydrogen-bonded Turntrans-85.8-2.5179.1-69.6171.3000113.5C336 E342 I352 F378 Y384 L387 E391C336-L340 WeakPolarHBondContact O-CB 3.33Å; C336-L340 VanDerWaalsContact O-CG 3.3Å; C336-L340 WeakPolarHBondContact O-CG 3.39Å; C336-L340 PolarHBondContact O-N 3.02Å; L340-E342 PolarHBondContact O-N 3Å; L340-I352 HydrophobicContact CD2-CG2 3.97Å; L340-F378 HydrophobicContact CD1-CE1 3.95Å; L340-F378 HydrophobicContact CD2-CE1 4.23Å; L340-F378 HydrophobicContact CG-CE1 3.91Å; L340-F378 HydrophobicContact CG-CZ 4.27Å; L340-Y384 HydrophobicContact CD1-CD1 4.13Å; L340-L387 HydrophobicContact CD1-CB 3.79Å; L340-L387 HydrophobicContact CD1-CD1 3.83Å; L340-L387 HydrophobicContact CD1-CG 4.43Å; L340-E391 HydrophobicContact CD2-CG 4.31Å
341R88.8Confident87.4Confident164 Ų16460 Ų6062%0.61930%0.302SS*.PPolyproline II helixtrans-70.8123.9-179.7-172.8176.1-179.4-176.8-1.2110.4Q337 A338 C339Q337-R341 PolarHBondContact O-N 2.92Å; A338-R341 WeakPolarHBondContact O-CB 3.1Å; A338-R341 PolarHBondContact O-N 2.69Å; C339-R341 VanDerWaalsContact C-N 3.34Å
342E82.2Confident87.6Confident124 Ų12460.2 Ų60.258%0.57930%0.303SS*.PPolyproline II helixtrans-84.4140.7167.8-63.3179.7157.300109.6L340 C350L340-E342 PolarHBondContact O-N 3Å; E342-C350 HydrophobicContact CG-CB 4.22Å
343E77.2Confident87.8Confident86 Ų8659.4 Ų59.440%0.40230%0.3SS..PPolyproline II helixtrans-80.6128.1172.9-74.1-176.5157.500109K199 D345 S346K199-E343 IonicContact NZ-OE1 3.9Å; K199-E343 PolarHBondContact NZ-OE1 3.02Å; E343-D345 PolarHBondContact O-N 3.14Å; E343-S346 VanDerWaalsContact O-CB 3.3Å; E343-S346 WeakPolarHBondContact O-CB 3.03Å; E343-S346 PolarHBondContact O-N 2.95Å
344P70.8Confident87.9Confident109 Ų10960 Ų6071%0.70830%0.301SS*.THydrogen-bonded Turntrans-56139177.3-23.833.7000111.5S346P344-S346 PolarHBondContact O-N 3.01Å; P344-S346 VanDerWaalsContact O-N 3.15Å
345D67.9Low88Confident177 Ų17760.2 Ų60.295%0.94730%0.302SS*.THydrogen-bonded Turntrans61.114.4179.6-50-48.7000115.5E343E343-D345 PolarHBondContact O-N 3.14Å
346S74.5Confident88Confident41 Ų4159.7 Ų59.729%0.28730%0.3SS..  trans-99130.6175.9-161.70000111E343 P344 N348E343-S346 VanDerWaalsContact O-CB 3.3Å; E343-S346 WeakPolarHBondContact O-CB 3.03Å; E343-S346 PolarHBondContact O-N 2.95Å; P344-S346 PolarHBondContact O-N 3.01Å; P344-S346 VanDerWaalsContact O-N 3.15Å; S346-N348 PolarHBondContact O-N 2.88Å; S346-N348 PolarHBondContact OG-ND2 2.76Å
347E78Confident88Confident203 Ų20361.2 Ų61.295%0.94931%0.308SS*.  trans-75.6-5.5169.8-66.9-169.7161.200112.7
348N82.6Confident87.9Confident94 Ų9459.4 Ų59.450%0.50330%0.297SS..SBendtrans-73138.1-177.8-68.1-66.9000111.7S346S346-N348 PolarHBondContact O-N 2.88Å; S346-N348 PolarHBondContact OG-ND2 2.76Å
349P90.9Very high88Confident33 Ų3359.1 Ų59.121%0.21429%0.294CS..PPolyproline II helixtrans-57.8159.2170.1-22.232.8000112.6R354 L357P349-R354 HydrophobicContact CB-CG 4.24Å; P349-R354 VanDerWaalsContact O-CD 3.29Å; P349-R354 WeakPolarHBondContact O-CD 3.43Å; P349-R354 WeakPolarHBondContact O-CG 3.19Å; P349-L357 HydrophobicContact CG-CD1 3.95Å
350C93.5Very high87.9Confident4 Ų460.3 Ų60.33%0.02730%0.304CS..PPolyproline II helixtrans-57159170.8720000111.8E342 I352 S353 R354E342-C350 HydrophobicContact CG-CB 4.22Å; C350-I352 VanDerWaalsContact C-N 3.3Å; C350-I352 PolarHBondContact O-N 3.35Å; C350-S353 PolarHBondContact O-N 3.48Å; C350-S353 PolarHBondContact SG-OG 3.22Å; C350-S353 VanDerWaalsContact SG-OG 3.33Å; C350-R354 PolarHBondContact O-N 2.9Å
351L93.8Very high87.8Confident19 Ų1964.8 Ų64.810%0.09932%0.322CS..Hα-helixtrans-58.2-37.2-168.5-66.2176.5000113.7I198 V202 C339 L355I198-L351 HydrophobicContact CG2-CB 4.39Å; I198-L351 HydrophobicContact CG2-CD1 3.83Å; V202-L351 HydrophobicContact CB-CD2 4.34Å; V202-L351 HydrophobicContact CG1-CD2 4.14Å; V202-L351 HydrophobicContact CG2-CB 3.99Å; V202-L351 HydrophobicContact CG2-CD2 4.29Å; C339-L351 PolarHBondContact O-N 2.79Å; C339-L351 VanDerWaalsContact O-N 3.1Å; L351-L355 PolarHBondContact O-N 3.32Å
352I94.7Very high87.9Confident4 Ų457.3 Ų57.32%0.02129%0.294CS..Hα-helixtrans-70-40.4175-172.859.8000112C339 L340 C350 R354 L355 M356 L370 I374 F378 F388C339-I352 HydrophobicContact CB-CB 4.12Å; C339-I352 HydrophobicContact CB-CG2 4.37Å; C339-I352 PolarHBondContact O-N 2.65Å; L340-I352 HydrophobicContact CD2-CG2 3.97Å; C350-I352 VanDerWaalsContact C-N 3.3Å; C350-I352 PolarHBondContact O-N 3.35Å; I352-R354 VanDerWaalsContact C-N 3.33Å; I352-R354 PolarHBondContact O-N 2.66Å; I352-L355 PolarHBondContact O-N 3.2Å; I352-L355 VanDerWaalsContact O-N 3.16Å; I352-M356 WeakPolarHBondContact O-CG 3.29Å; I352-M356 PolarHBondContact O-N 2.99Å; I352-L370 HydrophobicContact CD1-CD1 4Å; I352-I374 HydrophobicContact CD1-CD1 4.18Å; I352-I374 HydrophobicContact CD1-CG1 4.03Å; I352-F378 HydrophobicContact CB-CE2 4.47Å; I352-F378 HydrophobicContact CB-CZ 4.3Å; I352-F378 HydrophobicContact CD1-CE2 4.3Å; I352-F378 HydrophobicContact CG1-CE2 4.07Å; I352-F378 HydrophobicContact CG1-CZ 4.24Å; I352-F378 HydrophobicContact CG2-CZ 4.17Å; I352-F388 HydrophobicContact CD1-CE2 4.19Å; I352-F388 HydrophobicContact CG1-CD2 3.93Å; I352-F388 HydrophobicContact CG1-CE2 3.77Å
353S95.1Very high88.4Confident0 Ų052.8 Ų52.80%027%0.272CS..Hα-helixtrans-66.9-33.9177.1-63.50000112.2C350 M356 L357 E391C350-S353 PolarHBondContact O-N 3.48Å; C350-S353 PolarHBondContact SG-OG 3.22Å; C350-S353 VanDerWaalsContact SG-OG 3.33Å; S353-M356 PolarHBondContact O-N 2.98Å; S353-L357 WeakPolarHBondContact O-CB 3.2Å; S353-L357 VanDerWaalsContact O-CG 3.26Å; S353-L357 WeakPolarHBondContact O-CG 3.47Å; S353-L357 PolarHBondContact O-N 3.38Å; S353-E391 PolarHBondContact OG-OE2 3.05Å
354R94.3Very high89Confident42 Ų4250.5 Ų50.516%0.15826%0.261CS..Hα-helixtrans-58.7-46.6168.4-73.8171.964.8-174.6-0.6111.7V202 P349 C350 I352 W358V202-R354 HydrophobicContact CG1-CB 4.35Å; P349-R354 HydrophobicContact CB-CG 4.24Å; P349-R354 VanDerWaalsContact O-CD 3.29Å; P349-R354 WeakPolarHBondContact O-CD 3.43Å; P349-R354 WeakPolarHBondContact O-CG 3.19Å; C350-R354 PolarHBondContact O-N 2.9Å; I352-R354 VanDerWaalsContact C-N 3.33Å; I352-R354 PolarHBondContact O-N 2.66Å; R354-W358 WeakPolarHBondContact O-CB 3.46Å; R354-W358 VanDerWaalsContact O-CD1 3.25Å; R354-W358 PolarHBondContact O-N 3.12Å
355L94.3Very high89.9Confident14 Ų1446.1 Ų46.17%0.07324%0.235CC..Hα-helixtrans-65.4-39.9176.9-75.7168.6000112.8V202 T205 I206 L351 I352 W358 D359 L370V202-L355 HydrophobicContact CB-CG 4.47Å; V202-L355 HydrophobicContact CG1-CD2 4.48Å; V202-L355 HydrophobicContact CG1-CG 4.23Å; V202-L355 HydrophobicContact CG2-CD1 3.63Å; V202-L355 HydrophobicContact CG2-CD2 4.49Å; V202-L355 HydrophobicContact CG2-CG 3.96Å; T205-L355 HydrophobicContact CG2-CD2 4.17Å; I206-L355 HydrophobicContact CG2-CD2 4.12Å; L351-L355 PolarHBondContact O-N 3.32Å; I352-L355 PolarHBondContact O-N 3.2Å; I352-L355 VanDerWaalsContact O-N 3.16Å; L355-W358 PolarHBondContact O-N 3.15Å; L355-D359 PolarHBondContact O-N 3.25Å; L355-L370 HydrophobicContact CB-CD1 3.85Å; L355-L370 HydrophobicContact CB-CD2 4.28Å; L355-L370 HydrophobicContact CD1-CD1 4.05Å; L355-L370 HydrophobicContact CG-CD1 4.48Å
356M95.4Very high91.1Very high0 Ų037.8 Ų37.80%019%0.191CC..Hα-helixtrans-62.4-48.2176.9-67.4-166.5-69.100112I352 S353 W358 D359 F388 E391 F392 L399 I414I352-M356 WeakPolarHBondContact O-CG 3.29Å; I352-M356 PolarHBondContact O-N 2.99Å; S353-M356 PolarHBondContact O-N 2.98Å; M356-W358 PolarHBondContact O-N 3.37Å; M356-D359 VanDerWaalsContact O-CB 3.29Å; M356-D359 WeakPolarHBondContact O-CB 3.37Å; M356-D359 PolarHBondContact O-N 3.25Å; M356-D359 VanDerWaalsContact O-N 3.1Å; M356-F388 HydrophobicContact CE-CE2 4.45Å; M356-F388 HydrophobicContact CG-CE2 4.41Å; M356-F388 HydrophobicContact SD-CD2 4.49Å; M356-F388 HydrophobicContact SD-CE2 3.59Å; M356-F388 VanDerWaalsContact SD-CE2 3.59Å; M356-F388 HydrophobicContact SD-CZ 3.61Å; M356-E391 HydrophobicContact CE-CB 3.99Å; M356-F392 HydrophobicContact SD-CB 4.41Å; M356-F392 HydrophobicContact SD-CD2 4.15Å; M356-L399 VanDerWaalsContact C-CD2 3.49Å; M356-L399 HydrophobicContact CB-CD1 4.43Å; M356-L399 HydrophobicContact CB-CD2 4.17Å; M356-L399 WeakPolarHBondContact O-CD2 3.42Å; M356-I414 HydrophobicContact CB-CG1 4.29Å; M356-I414 HydrophobicContact CG-CD1 3.92Å; M356-I414 HydrophobicContact CG-CG1 3.85Å; M356-I414 HydrophobicContact SD-CD1 4.46Å; M356-I414 HydrophobicContact SD-CG1 4.2Å
357L95.2Very high92Very high31 Ų3135.9 Ų35.916%0.16218%0.177CC..THydrogen-bonded Turntrans-65.4-5.5176.6-70170.8000114.1P349 S353 Y395 Q398 L399P349-L357 HydrophobicContact CG-CD1 3.95Å; S353-L357 WeakPolarHBondContact O-CB 3.2Å; S353-L357 VanDerWaalsContact O-CG 3.26Å; S353-L357 WeakPolarHBondContact O-CG 3.47Å; S353-L357 PolarHBondContact O-N 3.38Å; L357-Y395 HydrophobicContact CD1-CD1 3.9Å; L357-Y395 HydrophobicContact CD1-CE1 3.88Å; L357-Y395 HydrophobicContact CD1-CG 4.29Å; L357-Y395 HydrophobicContact CD2-CD1 3.76Å; L357-Y395 HydrophobicContact CD2-CG 3.96Å; L357-Y395 HydrophobicContact CG-CD1 4.2Å; L357-Y395 HydrophobicContact CG-CG 4.24Å; L357-Q398 HydrophobicContact CD2-CB 4.35Å; L357-Q398 VanDerWaalsContact CD2-CD 3.49Å; L357-Q398 HydrophobicContact CD2-CG 3.99Å; L357-L399 HydrophobicContact CD2-CD2 4.22Å
358W94.5Very high92.6Very high53 Ų5332 Ų3220%0.20116%0.157CC..THydrogen-bonded Turntrans-106.7-12.3178-96.984.1000113.4I206 E208 R354 L355 M356 A360 K361 L362I206-W358 HydrophobicContact CB-CD2 3.6Å; I206-W358 HydrophobicContact CB-CE3 3.95Å; I206-W358 HydrophobicContact CB-CG 3.83Å; I206-W358 HydrophobicContact CB-CZ2 4.45Å; I206-W358 HydrophobicContact CB-CZ3 4.49Å; I206-W358 HydrophobicContact CG2-CB 3.71Å; I206-W358 HydrophobicContact CG2-CD2 3.74Å; I206-W358 HydrophobicContact CG2-CE3 4.14Å; I206-W358 HydrophobicContact CG2-CG 3.49Å; I206-W358 VanDerWaalsContact CG2-CG 3.49Å; E208-W358 HydrophobicContact CG-CH2 3.35Å; E208-W358 HydrophobicContact CG-CZ2 3.89Å; E208-W358 HydrophobicContact CG-CZ3 4.41Å; E208-W358 WeakPolarHBondContact OE1-CH2 3.27Å; E208-W358 WeakPolarHBondContact OE1-CZ2 3.44Å; R354-W358 WeakPolarHBondContact O-CB 3.46Å; R354-W358 VanDerWaalsContact O-CD1 3.25Å; R354-W358 PolarHBondContact O-N 3.12Å; L355-W358 PolarHBondContact O-N 3.15Å; M356-W358 PolarHBondContact O-N 3.37Å; W358-A360 PolarHBondContact O-N 3.44Å; W358-K361 HydrophobicContact CD2-CD 4.22Å; W358-K361 HydrophobicContact CE3-CB 3.69Å; W358-K361 HydrophobicContact CE3-CD 3.7Å; W358-K361 HydrophobicContact CE3-CG 4.33Å; W358-K361 HydrophobicContact CH2-CD 3.39Å; W358-K361 HydrophobicContact CZ2-CD 3.98Å; W358-K361 HydrophobicContact CZ3-CB 3.62Å; W358-K361 HydrophobicContact CZ3-CD 3.26Å; W358-K361 HydrophobicContact CZ3-CG 4.13Å; W358-K361 PolarHBondContact O-N 3.32Å; W358-L362 HydrophobicContact CE3-CD2 4.34Å; W358-L362 WeakPolarHBondContact O-CG 3.5Å; W358-L362 PolarHBondContact O-N 3.2Å
359D94.9Very high93Very high3 Ų328.3 Ų28.32%0.01614%0.138CC..G310 helixtrans-46.6-51.8-172.5-178.473.8000113.3L355 M356 K361 L362 R367 H371 S413 I414L355-D359 PolarHBondContact O-N 3.25Å; M356-D359 VanDerWaalsContact O-CB 3.29Å; M356-D359 WeakPolarHBondContact O-CB 3.37Å; M356-D359 PolarHBondContact O-N 3.25Å; M356-D359 VanDerWaalsContact O-N 3.1Å; D359-K361 PolarHBondContact O-N 3.43Å; D359-K361 VanDerWaalsContact O-N 3.16Å; D359-L362 WeakPolarHBondContact O-CB 3.17Å; D359-L362 PolarHBondContact O-N 2.92Å; D359-R367 PolarHBondContact O-NE 2.96Å; D359-R367 PolarHBondContact O-NH2 2.69Å; D359-R367 IonicContact OD2-NH1 2.99Å; D359-H371 IonicContact OD1-NE2 2.73Å; D359-H371 PolarHBondContact OD1-NE2 3.38Å; D359-S413 WeakPolarHBondContact OD2-CA 3.46Å; D359-S413 WeakPolarHBondContact OD2-CB 3.47Å; D359-S413 PolarHBondContact OD2-OG 3.48Å; D359-I414 HydrophobicContact CB-CB 3.96Å; D359-I414 HydrophobicContact CB-CG2 3.65Å; D359-I414 PolarHBondContact OD1-N 2.69Å; D359-I414 PolarHBondContact OD2-N 2.93Å
360A92.8Very high93.1Very high27 Ų2727 Ų2722%0.22313%0.129CC..G310 helixtrans-64.2-20.1-177.800000114.5W358 R367 E402 D406W358-A360 PolarHBondContact O-N 3.44Å; A360-R367 PolarHBondContact O-NH2 2.9Å; A360-R367 VanDerWaalsContact O-NH2 3.13Å; A360-E402 HydrophobicContact CB-CB 3.82Å; A360-D406 HydrophobicContact CB-CB 4.35Å
361K91.7Very high93Very high132 Ų13227.5 Ų27.557%0.57413%0.131SC*.G310 helixtrans-92.4-15.2173.5-66.4-178.5175.1-178.20113.1E208 W358 D359E208-K361 IonicContact OE1-NZ 2.83Å; E208-K361 PolarHBondContact OE1-NZ 3.27Å; W358-K361 HydrophobicContact CD2-CD 4.22Å; W358-K361 HydrophobicContact CE3-CB 3.69Å; W358-K361 HydrophobicContact CE3-CD 3.7Å; W358-K361 HydrophobicContact CE3-CG 4.33Å; W358-K361 HydrophobicContact CH2-CD 3.39Å; W358-K361 HydrophobicContact CZ2-CD 3.98Å; W358-K361 HydrophobicContact CZ3-CB 3.62Å; W358-K361 HydrophobicContact CZ3-CD 3.26Å; W358-K361 HydrophobicContact CZ3-CG 4.13Å; W358-K361 PolarHBondContact O-N 3.32Å; D359-K361 PolarHBondContact O-N 3.43Å; D359-K361 VanDerWaalsContact O-N 3.16Å
362L92.6Very high92.8Very high7 Ų729.4 Ų29.44%0.03714%0.139CC..SBendtrans-77.7138.7-178.2-65.5-176.4000110.8T205 W358 D359 A366 R367 L370T205-L362 HydrophobicContact CG2-CD1 4.04Å; T205-L362 HydrophobicContact CG2-CD2 3.66Å; T205-L362 WeakPolarHBondContact O-CD2 3.5Å; W358-L362 HydrophobicContact CE3-CD2 4.34Å; W358-L362 WeakPolarHBondContact O-CG 3.5Å; W358-L362 PolarHBondContact O-N 3.2Å; D359-L362 WeakPolarHBondContact O-CB 3.17Å; D359-L362 PolarHBondContact O-N 2.92Å; L362-A366 HydrophobicContact CB-CB 4.11Å; L362-A366 HydrophobicContact CD1-CB 4.38Å; L362-A366 HydrophobicContact CD2-CB 4.39Å; L362-R367 HydrophobicContact CB-CG 3.72Å; L362-R367 PolarHBondContact O-NE 3.31Å; L362-R367 PolarHBondContact O-NH2 3.26Å; L362-L370 HydrophobicContact CD1-CD2 4.4Å
363Y91.5Very high92.7Very high30 Ų3029.9 Ų29.912%0.11814%0.141CC..  trans-70152.4170.962.1-83.8000111.5E266 R268 L315 G365 A366 R367E266-Y363 WeakPolarHBondContact O-CD2 3.35Å; R268-Y363 HydrophobicContact CG-CD2 3.94Å; R268-Y363 HydrophobicContact CG-CE2 4.18Å; R268-Y363 HydrophobicContact CG-CG 4.19Å; R268-Y363 VanDerWaalsContact CZ-CE1 3.43Å; R268-Y363 VanDerWaalsContact NE-CZ 3.32Å; R268-Y363 PolarHBondContact NH2-OH 3.36Å; L315-Y363 HydrophobicContact CD1-CE2 3.86Å; L315-Y363 VanDerWaalsContact CD1-OH 3.25Å; L315-Y363 WeakPolarHBondContact CD1-OH 3.38Å; Y363-G365 VanDerWaalsContact C-N 3.29Å; Y363-G365 PolarHBondContact O-N 3.37Å; Y363-A366 HydrophobicContact CD1-CB 4.15Å; Y363-A366 HydrophobicContact CD2-CB 4.46Å; Y363-A366 HydrophobicContact CE1-CB 3.91Å; Y363-A366 HydrophobicContact CE2-CB 4.26Å; Y363-A366 HydrophobicContact CG-CB 4.41Å; Y363-A366 WeakPolarHBondContact O-CA 2.86Å; Y363-A366 WeakPolarHBondContact O-CB 3.33Å; Y363-A366 PolarHBondContact O-N 2.73Å; Y363-R367 PolarHBondContact O-N 2.93Å; Y363-R367 VanDerWaalsContact O-N 3.15Å
364K90.3Very high92.7Very high38 Ų3829.9 Ų29.917%0.16514%0.142CC..Hα-helixtrans-34.6-50.1-180-160.6154.8174.3176.50115E234 D264 A366 K368 I412E234-K364 IonicContact OE1-NZ 2.27Å; E234-K364 PolarHBondContact OE1-NZ 3.46Å; E234-K364 IonicContact OE2-NZ 3.06Å; D264-K364 VanDerWaalsContact O-CD 3.27Å; D264-K364 WeakPolarHBondContact O-CD 3.45Å; D264-K364 WeakPolarHBondContact O-CE 3.12Å; D264-K364 PolarHBondContact O-NZ 3.33Å; D264-K364 IonicContact OD1-NZ 2.93Å; D264-K364 PolarHBondContact OD1-NZ 3.29Å; K364-A366 PolarHBondContact O-N 3.28Å; K364-K368 WeakPolarHBondContact O-CB 3.42Å; K364-K368 PolarHBondContact O-N 3.37Å; K364-I412 HydrophobicContact CB-CD1 4.46Å; K364-I412 HydrophobicContact CD-CD1 4.15Å; K364-I412 HydrophobicContact CG-CD1 3.79Å
365G90.4Very high92.4Very high16 Ų1628.3 Ų28.317%0.16514%0.136CC..Hα-helixtrans-63.5-37.517800000115E266 Y363 I369E266-G365 WeakPolarHBondContact O-CA 3.16Å; E266-G365 PolarHBondContact O-N 3.39Å; Y363-G365 VanDerWaalsContact C-N 3.29Å; Y363-G365 PolarHBondContact O-N 3.37Å; G365-I369 PolarHBondContact O-N 2.82Å
366A92.9Very high92.1Very high2 Ų228.6 Ų28.62%0.01714%0.139CC..Hα-helixtrans-73-43.6176.900000112T205 L315 L362 Y363 K364 K368 I369 L370T205-A366 HydrophobicContact CG2-CB 4.14Å; L315-A366 HydrophobicContact CD1-CB 4.37Å; L315-A366 HydrophobicContact CD2-CB 3.95Å; L362-A366 HydrophobicContact CB-CB 4.11Å; L362-A366 HydrophobicContact CD1-CB 4.38Å; L362-A366 HydrophobicContact CD2-CB 4.39Å; Y363-A366 HydrophobicContact CD1-CB 4.15Å; Y363-A366 HydrophobicContact CD2-CB 4.46Å; Y363-A366 HydrophobicContact CE1-CB 3.91Å; Y363-A366 HydrophobicContact CE2-CB 4.26Å; Y363-A366 HydrophobicContact CG-CB 4.41Å; Y363-A366 WeakPolarHBondContact O-CA 2.86Å; Y363-A366 WeakPolarHBondContact O-CB 3.33Å; Y363-A366 PolarHBondContact O-N 2.73Å; K364-A366 PolarHBondContact O-N 3.28Å; A366-K368 VanDerWaalsContact C-N 3.27Å; A366-K368 PolarHBondContact O-N 2.96Å; A366-I369 PolarHBondContact O-N 3.42Å; A366-L370 PolarHBondContact O-N 2.75Å
367R92.9Very high91.9Very high1 Ų128.6 Ų28.60%0.00414%0.139CC..Hα-helixtrans-58.5-40.4174.2-59.6-168.5-161.2-159.67.5111.9D359 A360 L362 Y363 I369 L370 H371 D406 H408 I412D359-R367 PolarHBondContact O-NE 2.96Å; D359-R367 PolarHBondContact O-NH2 2.69Å; D359-R367 IonicContact OD2-NH1 2.99Å; A360-R367 PolarHBondContact O-NH2 2.9Å; A360-R367 VanDerWaalsContact O-NH2 3.13Å; L362-R367 HydrophobicContact CB-CG 3.72Å; L362-R367 PolarHBondContact O-NE 3.31Å; L362-R367 PolarHBondContact O-NH2 3.26Å; Y363-R367 PolarHBondContact O-N 2.93Å; Y363-R367 VanDerWaalsContact O-N 3.15Å; R367-I369 PolarHBondContact O-N 2.83Å; R367-L370 WeakPolarHBondContact O-CB 3.45Å; R367-L370 PolarHBondContact O-N 2.92Å; R367-H371 PolarHBondContact O-CD2 3.08Å; R367-H371 PolarHBondContact O-N 2.8Å; R367-D406 IonicContact CZ-OD1 3.45Å; R367-D406 IonicContact CZ-OD2 2.76Å; R367-D406 IonicContact NH1-OD1 3.44Å; R367-D406 IonicContact NH1-OD2 3.46Å; R367-D406 PolarHBondContact NH1-OD2 3.37Å; R367-D406 IonicContact NH2-OD1 3.3Å; R367-D406 PolarHBondContact NH2-OD1 3.35Å; R367-D406 IonicContact NH2-OD2 3.76Å; R367-D406 PolarHBondContact NH2-OD2 3.4Å; R367-H408 PolarHBondContact NH2-ND1 2.75Å; R367-I412 VanDerWaalsContact CB-O 3.31Å; R367-I412 WeakPolarHBondContact CB-O 3.32Å; R367-I412 WeakPolarHBondContact CD-O 3.35Å
368K89.9Confident91.8Very high121 Ų12127.1 Ų27.153%0.52613%0.132SC..Hα-helixtrans-59.2-45175.7-178.6-179.8168.9-171.50112.7K364 A366 H371 E372K364-K368 WeakPolarHBondContact O-CB 3.42Å; K364-K368 PolarHBondContact O-N 3.37Å; A366-K368 VanDerWaalsContact C-N 3.27Å; A366-K368 PolarHBondContact O-N 2.96Å; K368-H371 PolarHBondContact O-N 2.95Å; K368-E372 WeakPolarHBondContact CE-OE1 3.28Å; K368-E372 IonicContact NZ-OE1 3.44Å; K368-E372 WeakPolarHBondContact O-CB 3.43Å; K368-E372 WeakPolarHBondContact O-CG 3.3Å; K368-E372 PolarHBondContact O-N 3.28Å
369I91.3Very high91.7Very high18 Ų1824.8 Ų24.89%0.09212%0.123CC..Hα-helixtrans-65.7-39.2176.2-65.7-62.5000111.2L315 S319 G365 A366 R367 E372 L373L315-I369 HydrophobicContact CB-CG1 4.18Å; L315-I369 HydrophobicContact CD2-CB 4.23Å; L315-I369 HydrophobicContact CD2-CG1 4.17Å; L315-I369 HydrophobicContact CD2-CG2 4.5Å; S319-I369 WeakPolarHBondContact OG-CD1 3.49Å; G365-I369 PolarHBondContact O-N 2.82Å; A366-I369 PolarHBondContact O-N 3.42Å; R367-I369 PolarHBondContact O-N 2.83Å; I369-E372 PolarHBondContact O-N 3.28Å; I369-L373 HydrophobicContact CG2-CD1 3.96Å; I369-L373 HydrophobicContact CG2-CG 4.33Å; I369-L373 WeakPolarHBondContact O-CB 3.43Å; I369-L373 VanDerWaalsContact O-CG 3.27Å; I369-L373 WeakPolarHBondContact O-CG 3.47Å; I369-L373 PolarHBondContact O-N 3.12Å
370L93.3Very high91.2Very high6 Ų626.3 Ų26.33%0.03113%0.13CC..Hα-helixtrans-58.3-48.8173.617558.3000111.8I352 L355 L362 A366 R367 L373 I374 I414I352-L370 HydrophobicContact CD1-CD1 4Å; L355-L370 HydrophobicContact CB-CD1 3.85Å; L355-L370 HydrophobicContact CB-CD2 4.28Å; L355-L370 HydrophobicContact CD1-CD1 4.05Å; L355-L370 HydrophobicContact CG-CD1 4.48Å; L362-L370 HydrophobicContact CD1-CD2 4.4Å; A366-L370 PolarHBondContact O-N 2.75Å; R367-L370 WeakPolarHBondContact O-CB 3.45Å; R367-L370 PolarHBondContact O-N 2.92Å; L370-L373 PolarHBondContact O-N 3.3Å; L370-I374 HydrophobicContact CD1-CD1 3.76Å; L370-I374 HydrophobicContact CD1-CG1 4.3Å; L370-I374 HydrophobicContact CG-CD1 3.97Å; L370-I374 WeakPolarHBondContact O-CG1 3.47Å; L370-I374 PolarHBondContact O-N 2.85Å; L370-I414 HydrophobicContact CD2-CD1 4.21Å; L370-I414 HydrophobicContact CG-CD1 4.4Å
371H91.8Very high90.7Very high14 Ų1426.4 Ų26.47%0.06513%0.126CC..Hα-helixtrans-60.2-49.2175.8-81.1-133.4000111.6D359 R367 K368 L373 I374 F375 S411 I412 S413 I414D359-H371 IonicContact OD1-NE2 2.73Å; D359-H371 PolarHBondContact OD1-NE2 3.38Å; R367-H371 PolarHBondContact O-CD2 3.08Å; R367-H371 PolarHBondContact O-N 2.8Å; K368-H371 PolarHBondContact O-N 2.95Å; H371-L373 VanDerWaalsContact C-N 3.3Å; H371-L373 PolarHBondContact O-N 3.48Å; H371-I374 PolarHBondContact O-N 3.22Å; H371-I374 VanDerWaalsContact O-N 3.14Å; H371-F375 HydrophobicContact CB-CD2 4.25Å; H371-F375 HydrophobicContact CB-CE2 4.17Å; H371-F375 WeakPolarHBondContact O-CD2 3.47Å; H371-F375 PolarHBondContact O-N 2.74Å; H371-S411 PolarHBondContact CE1-O 2.91Å; H371-S411 VanDerWaalsContact CE1-O 3.25Å; H371-I412 VanDerWaalsContact CE1-C 3.46Å; H371-I412 PolarHBondContact NE2-O 3.15Å; H371-S413 PolarHBondContact CE1-O 3.07Å; H371-S413 WeakPolarHBondContact NE2-CA 3.46Å; H371-S413 PolarHBondContact NE2-N 3.33Å; H371-S413 PolarHBondContact NE2-O 3.21Å; H371-I414 WeakPolarHBondContact NE2-CA 3.32Å; H371-I414 PolarHBondContact NE2-N 2.79Å
372E89.7Confident90.5Very high59 Ų5923.9 Ų23.928%0.27612%0.117SC..Hα-helixtrans-57.5-41.6178.1-78.6-177.8-163.200112.2N322 K368 I369 S376N322-E372 PolarHBondContact ND2-OE2 3.48Å; K368-E372 WeakPolarHBondContact CE-OE1 3.28Å; K368-E372 IonicContact NZ-OE1 3.44Å; K368-E372 WeakPolarHBondContact O-CB 3.43Å; K368-E372 WeakPolarHBondContact O-CG 3.3Å; K368-E372 PolarHBondContact O-N 3.28Å; I369-E372 PolarHBondContact O-N 3.28Å; E372-S376 VanDerWaalsContact O-CB 3.24Å; E372-S376 WeakPolarHBondContact O-CB 3.13Å; E372-S376 PolarHBondContact O-N 3.17Å; E372-S376 PolarHBondContact O-OG 3.4Å
373L92.4Very high90.4Very high13 Ų1329.9 Ų29.97%0.06815%0.145CC..Hα-helixtrans-64.6-41.2175.2-73.1171.3000112.3M321 N322 M325 F335 I369 L370 H371 S376 S377M321-L373 HydrophobicContact CB-CD2 4.17Å; M321-L373 HydrophobicContact CG-CD2 4.23Å; N322-L373 HydrophobicContact CB-CD2 4.36Å; M325-L373 HydrophobicContact CE-CD2 3.55Å; F335-L373 HydrophobicContact CE2-CD2 4.22Å; F335-L373 HydrophobicContact CZ-CB 4.22Å; F335-L373 HydrophobicContact CZ-CD1 4.49Å; F335-L373 HydrophobicContact CZ-CD2 4.09Å; I369-L373 HydrophobicContact CG2-CD1 3.96Å; I369-L373 HydrophobicContact CG2-CG 4.33Å; I369-L373 WeakPolarHBondContact O-CB 3.43Å; I369-L373 VanDerWaalsContact O-CG 3.27Å; I369-L373 WeakPolarHBondContact O-CG 3.47Å; I369-L373 PolarHBondContact O-N 3.12Å; L370-L373 PolarHBondContact O-N 3.3Å; H371-L373 VanDerWaalsContact C-N 3.3Å; H371-L373 PolarHBondContact O-N 3.48Å; L373-S376 WeakPolarHBondContact CA-OG 3.49Å; L373-S376 PolarHBondContact O-OG 3.42Å; L373-S377 WeakPolarHBondContact O-CB 3.37Å; L373-S377 PolarHBondContact O-N 3.08Å; L373-S377 VanDerWaalsContact O-N 3.17Å; L373-S377 PolarHBondContact O-OG 2.93Å
374I94.1Very high90.4Very high1 Ų129.2 Ų29.21%0.00514%0.142CC..Hα-helixtrans-68.5-45.9178.6-65.6161.5000111.3I352 L370 H371 S376 S377 F378 F379 F388 I414 L417I352-I374 HydrophobicContact CD1-CD1 4.18Å; I352-I374 HydrophobicContact CD1-CG1 4.03Å; L370-I374 HydrophobicContact CD1-CD1 3.76Å; L370-I374 HydrophobicContact CD1-CG1 4.3Å; L370-I374 HydrophobicContact CG-CD1 3.97Å; L370-I374 WeakPolarHBondContact O-CG1 3.47Å; L370-I374 PolarHBondContact O-N 2.85Å; H371-I374 PolarHBondContact O-N 3.22Å; H371-I374 VanDerWaalsContact O-N 3.14Å; I374-S376 PolarHBondContact O-N 3.37Å; I374-S377 PolarHBondContact O-N 3.17Å; I374-F378 HydrophobicContact CG2-CB 4.38Å; I374-F378 PolarHBondContact O-N 3.25Å; I374-F378 VanDerWaalsContact O-N 3.15Å; I374-F379 HydrophobicContact CG2-CD1 4.16Å; I374-F379 HydrophobicContact CG2-CD2 4.4Å; I374-F379 HydrophobicContact CG2-CE1 3.98Å; I374-F379 HydrophobicContact CG2-CE2 4.19Å; I374-F379 HydrophobicContact CG2-CG 4.38Å; I374-F379 HydrophobicContact CG2-CZ 4Å; I374-F379 PolarHBondContact O-N 3.48Å; I374-F388 HydrophobicContact CD1-CE2 3.87Å; I374-F388 HydrophobicContact CD1-CZ 3.89Å; I374-F388 HydrophobicContact CG1-CE2 4.07Å; I374-F388 HydrophobicContact CG1-CZ 4.4Å; I374-F388 HydrophobicContact CG2-CE1 4.27Å; I374-F388 HydrophobicContact CG2-CE2 4.14Å; I374-F388 HydrophobicContact CG2-CZ 3.99Å; I374-I414 HydrophobicContact CD1-CD1 3.43Å; I374-I414 VanDerWaalsContact CD1-CD1 3.43Å; I374-L417 HydrophobicContact CB-CD1 4.4Å; I374-L417 HydrophobicContact CD1-CD1 3.82Å; I374-L417 HydrophobicContact CG2-CD1 3.94Å
375F89.4Confident90.6Very high8 Ų827.6 Ų27.64%0.03514%0.135CC..Hα-helixtrans-62.2-42.3177.6-77-60.7000112.1V102 F148 H371 S377 F379 M380 L417 Q420V102-F375 HydrophobicContact CG1-CD2 4.32Å; V102-F375 HydrophobicContact CG2-CB 3.68Å; V102-F375 HydrophobicContact CG2-CD1 4.41Å; V102-F375 HydrophobicContact CG2-CD2 4.02Å; V102-F375 HydrophobicContact CG2-CG 3.79Å; F148-F375 AromaticContact CD1-CD1 3.47Å; F148-F375 HydrophobicContact CD1-CD1 3.47Å; F148-F375 VanDerWaalsContact CD1-CD1 3.47Å; F148-F375 AromaticContact CD1-CE1 3.43Å; F148-F375 HydrophobicContact CD1-CE1 3.43Å; F148-F375 VanDerWaalsContact CD1-CE1 3.43Å; F148-F375 AromaticContact CE1-CD1 3.97Å; F148-F375 HydrophobicContact CE1-CD1 3.97Å; F148-F375 AromaticContact CE1-CE1 3.9Å; F148-F375 HydrophobicContact CE1-CE1 3.9Å; F148-F375 HydrophobicContact CG-CD1 4.35Å; H371-F375 HydrophobicContact CB-CD2 4.25Å; H371-F375 HydrophobicContact CB-CE2 4.17Å; H371-F375 WeakPolarHBondContact O-CD2 3.47Å; H371-F375 PolarHBondContact O-N 2.74Å; F375-S377 VanDerWaalsContact C-N 3.32Å; F375-S377 PolarHBondContact O-N 3.13Å; F375-F379 AromaticContact CD1-CD2 3.58Å; F375-F379 HydrophobicContact CD1-CD2 3.58Å; F375-F379 HydrophobicContact CD1-CE2 4.2Å; F375-F379 AromaticContact CE1-CD2 3.64Å; F375-F379 HydrophobicContact CE1-CD2 3.64Å; F375-F379 AromaticContact CE1-CE2 3.86Å; F375-F379 HydrophobicContact CE1-CE2 3.86Å; F375-M380 WeakPolarHBondContact O-CG 3.26Å; F375-L417 HydrophobicContact CE1-CD2 4.21Å; F375-L417 HydrophobicContact CE2-CD2 3.8Å; F375-L417 HydrophobicContact CZ-CD2 3.41Å; F375-L417 VanDerWaalsContact CZ-CD2 3.41Å; F375-Q420 HydrophobicContact CE1-CG 4.11Å
376S87.8Confident90.8Very high21 Ų2130.9 Ų30.915%0.14715%0.145CC..Hα-helixtrans-77.7-10.9-179.1590000114.6N322 M325 R332 E372 L373 I374N322-S376 WeakPolarHBondContact OD1-CB 3.26Å; N322-S376 PolarHBondContact OD1-OG 3.39Å; M325-S376 WeakPolarHBondContact CE-OG 3.22Å; R332-S376 WeakPolarHBondContact CD-O 3.29Å; R332-S376 WeakPolarHBondContact CG-O 3.14Å; E372-S376 VanDerWaalsContact O-CB 3.24Å; E372-S376 WeakPolarHBondContact O-CB 3.13Å; E372-S376 PolarHBondContact O-N 3.17Å; E372-S376 PolarHBondContact O-OG 3.4Å; L373-S376 WeakPolarHBondContact CA-OG 3.49Å; L373-S376 PolarHBondContact O-OG 3.42Å; I374-S376 PolarHBondContact O-N 3.37Å
377S91.4Very high90.9Very high0 Ų033.9 Ų33.90%016%0.161CC..THydrogen-bonded Turntrans-121.4-85.2-178.965.90000112.6F335 L373 I374 F375 F379 M380F335-S377 WeakPolarHBondContact CD1-OG 3.07Å; F335-S377 VanDerWaalsContact CE1-OG 3.3Å; F335-S377 WeakPolarHBondContact CE1-OG 3.42Å; L373-S377 WeakPolarHBondContact O-CB 3.37Å; L373-S377 PolarHBondContact O-N 3.08Å; L373-S377 VanDerWaalsContact O-N 3.17Å; L373-S377 PolarHBondContact O-OG 2.93Å; I374-S377 PolarHBondContact O-N 3.17Å; F375-S377 VanDerWaalsContact C-N 3.32Å; F375-S377 PolarHBondContact O-N 3.13Å; S377-F379 VanDerWaalsContact C-N 3.3Å; S377-F379 PolarHBondContact O-N 3.41Å; S377-M380 PolarHBondContact O-N 3.16Å; S377-M380 VanDerWaalsContact O-N 3.13Å
378F93.1Very high91.1Very high0 Ų033.9 Ų33.90%016%0.161CC..G310 helixtrans-54.3-42.1-173.3-71.5-84.8000112.6F335 C336 C339 L340 I352 I374 M380 E381 K385 F388F335-F378 HydrophobicContact CE1-CE2 4.13Å; C336-F378 HydrophobicContact CB-CD1 4.06Å; C336-F378 HydrophobicContact CB-CE1 3.75Å; C336-F378 HydrophobicContact CB-CZ 4.07Å; C336-F378 VanDerWaalsContact SG-CD1 3.6Å; C339-F378 HydrophobicContact CB-CE2 4.15Å; C339-F378 HydrophobicContact CB-CZ 3.72Å; L340-F378 HydrophobicContact CD1-CE1 3.95Å; L340-F378 HydrophobicContact CD2-CE1 4.23Å; L340-F378 HydrophobicContact CG-CE1 3.91Å; L340-F378 HydrophobicContact CG-CZ 4.27Å; I352-F378 HydrophobicContact CB-CE2 4.47Å; I352-F378 HydrophobicContact CB-CZ 4.3Å; I352-F378 HydrophobicContact CD1-CE2 4.3Å; I352-F378 HydrophobicContact CG1-CE2 4.07Å; I352-F378 HydrophobicContact CG1-CZ 4.24Å; I352-F378 HydrophobicContact CG2-CZ 4.17Å; I374-F378 HydrophobicContact CG2-CB 4.38Å; I374-F378 PolarHBondContact O-N 3.25Å; I374-F378 VanDerWaalsContact O-N 3.15Å; F378-M380 VanDerWaalsContact C-N 3.34Å; F378-M380 PolarHBondContact O-N 3.16Å; F378-E381 PolarHBondContact O-N 3.06Å; F378-E381 VanDerWaalsContact O-O 3.12Å; F378-K385 WeakPolarHBondContact O-CA 3.26Å; F378-K385 WeakPolarHBondContact O-CB 3.34Å; F378-K385 PolarHBondContact O-N 2.68Å; F378-F388 HydrophobicContact CB-CB 4.16Å; F378-F388 HydrophobicContact CB-CG 4.4Å; F378-F388 HydrophobicContact CD1-CB 3.65Å; F378-F388 HydrophobicContact CD1-CD2 4.31Å; F378-F388 HydrophobicContact CD1-CG 4.34Å; F378-F388 HydrophobicContact CD2-CD2 4.3Å; F378-F388 HydrophobicContact CE1-CB 4.24Å; F378-F388 HydrophobicContact CG-CB 4.03Å; F378-F388 HydrophobicContact CG-CD2 4.16Å; F378-F388 HydrophobicContact CG-CG 4.32Å
379F90.7Very high91.4Very high3 Ų328.1 Ų28.11%0.01314%0.136CC..G310 helixtrans-80.3-12.7-175.2-70.9-0000114.7F148 I374 F375 S377 K385 F388 L417 Q420 M421F148-F379 HydrophobicContact CE1-CB 4.41Å; F148-F379 AromaticContact CE1-CD2 3.99Å; F148-F379 HydrophobicContact CE1-CD2 3.99Å; I374-F379 HydrophobicContact CG2-CD1 4.16Å; I374-F379 HydrophobicContact CG2-CD2 4.4Å; I374-F379 HydrophobicContact CG2-CE1 3.98Å; I374-F379 HydrophobicContact CG2-CE2 4.19Å; I374-F379 HydrophobicContact CG2-CG 4.38Å; I374-F379 HydrophobicContact CG2-CZ 4Å; I374-F379 PolarHBondContact O-N 3.48Å; F375-F379 AromaticContact CD1-CD2 3.58Å; F375-F379 HydrophobicContact CD1-CD2 3.58Å; F375-F379 HydrophobicContact CD1-CE2 4.2Å; F375-F379 AromaticContact CE1-CD2 3.64Å; F375-F379 HydrophobicContact CE1-CD2 3.64Å; F375-F379 AromaticContact CE1-CE2 3.86Å; F375-F379 HydrophobicContact CE1-CE2 3.86Å; S377-F379 VanDerWaalsContact C-N 3.3Å; S377-F379 PolarHBondContact O-N 3.41Å; F379-K385 HydrophobicContact CD1-CB 4.4Å; F379-K385 HydrophobicContact CD1-CG 3.84Å; F379-K385 HydrophobicContact CE1-CG 4.24Å; F379-K385 WeakPolarHBondContact O-CE 3.38Å; F379-K385 PolarHBondContact O-NZ 3.14Å; F379-F388 AromaticContact CE1-CD1 3.64Å; F379-F388 HydrophobicContact CE1-CD1 3.64Å; F379-F388 AromaticContact CE1-CE1 3.9Å; F379-F388 HydrophobicContact CE1-CE1 3.9Å; F379-F388 HydrophobicContact CE1-CG 4.46Å; F379-F388 HydrophobicContact CZ-CD1 4.2Å; F379-F388 AromaticContact CZ-CE1 3.99Å; F379-F388 HydrophobicContact CZ-CE1 3.99Å; F379-L417 HydrophobicContact CE2-CB 4.34Å; F379-L417 HydrophobicContact CE2-CD1 4.42Å; F379-L417 HydrophobicContact CE2-CD2 4.34Å; F379-L417 HydrophobicContact CZ-CB 4.17Å; F379-L417 HydrophobicContact CZ-CD1 4.34Å; F379-Q420 HydrophobicContact CD2-CB 3.97Å; F379-Q420 HydrophobicContact CD2-CG 4.38Å; F379-Q420 HydrophobicContact CE2-CB 3.4Å; F379-Q420 HydrophobicContact CE2-CG 3.85Å; F379-Q420 HydrophobicContact CZ-CB 3.92Å; F379-M421 HydrophobicContact CE1-CG 4.08Å; F379-M421 HydrophobicContact CE1-SD 4.22Å; F379-M421 HydrophobicContact CZ-CG 4.01Å; F379-M421 HydrophobicContact CZ-SD 4.23Å
380M84.9Confident91.6Very high36 Ų3629.8 Ų29.818%0.17714%0.144CC..G310 helixtrans-83.3-17173.9-61-58.7-73.800113.2L98 F375 S377 F378L98-M380 HydrophobicContact CB-CE 4.12Å; F375-M380 WeakPolarHBondContact O-CG 3.26Å; S377-M380 PolarHBondContact O-N 3.16Å; S377-M380 VanDerWaalsContact O-N 3.13Å; F378-M380 VanDerWaalsContact C-N 3.34Å; F378-M380 PolarHBondContact O-N 3.16Å
381E83.4Confident91.7Very high29 Ų2930.9 Ų30.914%0.13615%0.149CC..SBendtrans-125.2105.9-174.1-52.7-73.2143.800109.5S329 R332 Q333 F378 E383 Y384 K385S329-E381 WeakPolarHBondContact CB-OE1 3.34Å; R332-E381 HydrophobicContact CB-CG 4.19Å; R332-E381 IonicContact CZ-OE1 3.86Å; R332-E381 VanDerWaalsContact CZ-OE1 3.27Å; R332-E381 IonicContact NE-OE1 2.8Å; R332-E381 PolarHBondContact NE-OE1 3.25Å; R332-E381 IonicContact NH2-OE1 3.93Å; R332-E381 PolarHBondContact NH2-OE1 2.53Å; Q333-E381 HydrophobicContact CG-CG 4.34Å; Q333-E381 PolarHBondContact NE2-OE2 3.48Å; F378-E381 PolarHBondContact O-N 3.06Å; F378-E381 VanDerWaalsContact O-O 3.12Å; E381-E383 VanDerWaalsContact C-N 3.25Å; E381-E383 PolarHBondContact O-N 3.35Å; E381-E383 VanDerWaalsContact O-N 3.07Å; E381-Y384 HydrophobicContact CB-CD2 3.85Å; E381-Y384 PolarHBondContact O-N 2.72Å; E381-K385 PolarHBondContact O-N 3.49Å
382M86.1Confident92Very high79 Ų7930.2 Ų30.239%0.38915%0.146SC..Hα-helixtrans-55.8-32.3-169.4-75.5-65.3-7700115.2K385 K386 V424M382-K385 HydrophobicContact SD-CD 3.96Å; M382-K386 WeakPolarHBondContact O-CB 3.24Å; M382-K386 PolarHBondContact O-N 3.05Å; M382-K386 VanDerWaalsContact O-N 3.12Å; M382-V424 HydrophobicContact CE-CG1 4.17Å
383E90.3Very high92.4Very high132 Ų13227.6 Ų27.662%0.61713%0.134SC*.Hα-helixtrans-63.9-42.3174.5-176.9172.1-164.400111.9E381 K386 L387E381-E383 VanDerWaalsContact C-N 3.25Å; E381-E383 PolarHBondContact O-N 3.35Å; E381-E383 VanDerWaalsContact O-N 3.07Å; E383-K386 WeakPolarHBondContact O-CB 3.43Å; E383-L387 WeakPolarHBondContact O-CG 3.49Å; E383-L387 PolarHBondContact O-N 3.14Å
384Y93.1Very high92.6Very high16 Ų1631.4 Ų31.46%0.06315%0.15CC..Hα-helixtrans-80.9-32.2179.2-63.7-81.1000112Q333 C336 Q337 L340 E381 K386 L387 F388Q333-Y384 HydrophobicContact CB-CE2 3.95Å; Q333-Y384 HydrophobicContact CG-CD2 4.27Å; Q333-Y384 HydrophobicContact CG-CE2 3.65Å; C336-Y384 HydrophobicContact CB-CD1 3.25Å; C336-Y384 HydrophobicContact CB-CD2 4.4Å; C336-Y384 HydrophobicContact CB-CE1 3.79Å; C336-Y384 HydrophobicContact CB-CG 3.59Å; Q337-Y384 HydrophobicContact CG-CE1 3.95Å; Q337-Y384 PolarHBondContact NE2-OH 3.1Å; L340-Y384 HydrophobicContact CD1-CD1 4.13Å; E381-Y384 HydrophobicContact CB-CD2 3.85Å; E381-Y384 PolarHBondContact O-N 2.72Å; Y384-K386 PolarHBondContact O-N 3.24Å; Y384-L387 HydrophobicContact CD1-CD1 4.09Å; Y384-L387 HydrophobicContact CE1-CD1 4.39Å; Y384-L387 PolarHBondContact O-N 3.09Å; Y384-F388 WeakPolarHBondContact O-CB 3.19Å; Y384-F388 PolarHBondContact O-N 3.24Å
385K93.4Very high92.7Very high4 Ų433.5 Ų33.52%0.01716%0.158CC..Hα-helixtrans-53.8-43.9168-173.7-178.9-68.9-178.40110.6F378 F379 E381 M382 A389 L427F378-K385 WeakPolarHBondContact O-CA 3.26Å; F378-K385 WeakPolarHBondContact O-CB 3.34Å; F378-K385 PolarHBondContact O-N 2.68Å; F379-K385 HydrophobicContact CD1-CB 4.4Å; F379-K385 HydrophobicContact CD1-CG 3.84Å; F379-K385 HydrophobicContact CE1-CG 4.24Å; F379-K385 WeakPolarHBondContact O-CE 3.38Å; F379-K385 PolarHBondContact O-NZ 3.14Å; E381-K385 PolarHBondContact O-N 3.49Å; M382-K385 HydrophobicContact SD-CD 3.96Å; K385-A389 WeakPolarHBondContact O-CB 3.13Å; K385-A389 PolarHBondContact O-N 2.98Å; K385-L427 HydrophobicContact CD-CD2 4.37Å; K385-L427 HydrophobicContact CG-CD2 4.12Å
386K94.6Very high93.1Very high85 Ų8533.1 Ų33.137%0.3716%0.156SC..Hα-helixtrans-63.6-47.4176-179-166.2177.5-165.90112.6M382 E383 Y384 A389 M390 L427 H430M382-K386 WeakPolarHBondContact O-CB 3.24Å; M382-K386 PolarHBondContact O-N 3.05Å; M382-K386 VanDerWaalsContact O-N 3.12Å; E383-K386 WeakPolarHBondContact O-CB 3.43Å; Y384-K386 PolarHBondContact O-N 3.24Å; K386-A389 PolarHBondContact O-N 3Å; K386-M390 WeakPolarHBondContact O-CG 3.38Å; K386-M390 PolarHBondContact O-N 3.02Å; K386-M390 VanDerWaalsContact O-N 3.11Å; K386-L427 HydrophobicContact CB-CD1 4.06Å; K386-L427 HydrophobicContact CG-CD1 3.94Å; K386-H430 WeakPolarHBondContact CE-CD2 3.42Å; K386-H430 VanDerWaalsContact CE-CE1 3.46Å; K386-H430 WeakPolarHBondContact CE-CE1 3.48Å; K386-H430 WeakPolarHBondContact CE-NE2 3.36Å
387L95.4Very high93.5Very high66 Ų6635.8 Ų35.835%0.34617%0.165SC..Hα-helixtrans-64.3-43179.1-68.2171000112L340 E383 Y384 A389 M390 E391L340-L387 HydrophobicContact CD1-CB 3.79Å; L340-L387 HydrophobicContact CD1-CD1 3.83Å; L340-L387 HydrophobicContact CD1-CG 4.43Å; E383-L387 WeakPolarHBondContact O-CG 3.49Å; E383-L387 PolarHBondContact O-N 3.14Å; Y384-L387 HydrophobicContact CD1-CD1 4.09Å; Y384-L387 HydrophobicContact CE1-CD1 4.39Å; Y384-L387 PolarHBondContact O-N 3.09Å; L387-A389 VanDerWaalsContact C-N 3.34Å; L387-A389 PolarHBondContact O-N 2.94Å; L387-M390 PolarHBondContact O-N 3.44Å; L387-E391 PolarHBondContact O-N 3.22Å
388F96.4Very high93.7Very high0 Ų040.1 Ų40.10%019%0.185CC..Hα-helixtrans-59.5-44.2173.3177.4-90.5000111.7I352 M356 I374 F378 F379 Y384 M390 E391 F392 I414 L417 M421I352-F388 HydrophobicContact CD1-CE2 4.19Å; I352-F388 HydrophobicContact CG1-CD2 3.93Å; I352-F388 HydrophobicContact CG1-CE2 3.77Å; M356-F388 HydrophobicContact CE-CE2 4.45Å; M356-F388 HydrophobicContact CG-CE2 4.41Å; M356-F388 HydrophobicContact SD-CD2 4.49Å; M356-F388 HydrophobicContact SD-CE2 3.59Å; M356-F388 VanDerWaalsContact SD-CE2 3.59Å; M356-F388 HydrophobicContact SD-CZ 3.61Å; I374-F388 HydrophobicContact CD1-CE2 3.87Å; I374-F388 HydrophobicContact CD1-CZ 3.89Å; I374-F388 HydrophobicContact CG1-CE2 4.07Å; I374-F388 HydrophobicContact CG1-CZ 4.4Å; I374-F388 HydrophobicContact CG2-CE1 4.27Å; I374-F388 HydrophobicContact CG2-CE2 4.14Å; I374-F388 HydrophobicContact CG2-CZ 3.99Å; F378-F388 HydrophobicContact CB-CB 4.16Å; F378-F388 HydrophobicContact CB-CG 4.4Å; F378-F388 HydrophobicContact CD1-CB 3.65Å; F378-F388 HydrophobicContact CD1-CD2 4.31Å; F378-F388 HydrophobicContact CD1-CG 4.34Å; F378-F388 HydrophobicContact CD2-CD2 4.3Å; F378-F388 HydrophobicContact CE1-CB 4.24Å; F378-F388 HydrophobicContact CG-CB 4.03Å; F378-F388 HydrophobicContact CG-CD2 4.16Å; F378-F388 HydrophobicContact CG-CG 4.32Å; F379-F388 AromaticContact CE1-CD1 3.64Å; F379-F388 HydrophobicContact CE1-CD1 3.64Å; F379-F388 AromaticContact CE1-CE1 3.9Å; F379-F388 HydrophobicContact CE1-CE1 3.9Å; F379-F388 HydrophobicContact CE1-CG 4.46Å; F379-F388 HydrophobicContact CZ-CD1 4.2Å; F379-F388 AromaticContact CZ-CE1 3.99Å; F379-F388 HydrophobicContact CZ-CE1 3.99Å; Y384-F388 WeakPolarHBondContact O-CB 3.19Å; Y384-F388 PolarHBondContact O-N 3.24Å; F388-M390 VanDerWaalsContact C-N 3.27Å; F388-M390 PolarHBondContact O-N 3.48Å; F388-E391 PolarHBondContact O-N 3.38Å; F388-F392 HydrophobicContact CE1-CB 4.37Å; F388-F392 WeakPolarHBondContact O-CB 3.47Å; F388-F392 PolarHBondContact O-N 3.06Å; F388-I414 HydrophobicContact CZ-CD1 4.32Å; F388-L417 HydrophobicContact CE1-CD1 4.47Å; F388-L417 HydrophobicContact CZ-CD1 4.23Å; F388-M421 HydrophobicContact CD1-CE 4.43Å; F388-M421 HydrophobicContact CD1-SD 3.53Å; F388-M421 VanDerWaalsContact CD1-SD 3.53Å; F388-M421 HydrophobicContact CE1-CE 3.96Å; F388-M421 HydrophobicContact CE1-SD 3.65Å
389A97.1Very high93.9Very high0 Ų040.3 Ų40.30%019%0.186CC..Hα-helixtrans-63.8-30.9178.400000113.3K385 K386 L387 V393 M421 L427 L431K385-A389 WeakPolarHBondContact O-CB 3.13Å; K385-A389 PolarHBondContact O-N 2.98Å; K386-A389 PolarHBondContact O-N 3Å; L387-A389 VanDerWaalsContact C-N 3.34Å; L387-A389 PolarHBondContact O-N 2.94Å; A389-V393 WeakPolarHBondContact O-CG2 3.48Å; A389-V393 PolarHBondContact O-N 3.24Å; A389-M421 VanDerWaalsContact CA-SD 3.53Å; A389-M421 HydrophobicContact CB-CB 4.18Å; A389-M421 HydrophobicContact CB-CG 4.05Å; A389-M421 HydrophobicContact CB-SD 3.53Å; A389-M421 VanDerWaalsContact CB-SD 3.53Å; A389-L427 HydrophobicContact CB-CD1 4.07Å; A389-L427 HydrophobicContact CB-CD2 3.9Å; A389-L427 HydrophobicContact CB-CG 4.3Å; A389-L431 HydrophobicContact CB-CD1 4.13Å; A389-L431 HydrophobicContact CB-CD2 4.14Å
390M96Very high94.2Very high53 Ų5340.2 Ų40.226%0.26119%0.186SC..Hα-helixtrans-67.4-46.8172.7-69.6170.156.600111.6K386 L387 F388 F392 V393 K394 L431 Q435K386-M390 WeakPolarHBondContact O-CG 3.38Å; K386-M390 PolarHBondContact O-N 3.02Å; K386-M390 VanDerWaalsContact O-N 3.11Å; L387-M390 PolarHBondContact O-N 3.44Å; F388-M390 VanDerWaalsContact C-N 3.27Å; F388-M390 PolarHBondContact O-N 3.48Å; M390-F392 VanDerWaalsContact C-N 3.34Å; M390-F392 PolarHBondContact O-N 2.63Å; M390-V393 PolarHBondContact O-N 3.08Å; M390-K394 WeakPolarHBondContact O-CB 3.43Å; M390-K394 PolarHBondContact O-N 2.82Å; M390-L431 HydrophobicContact CG-CD2 4.31Å; M390-Q435 HydrophobicContact CG-CG 4.32Å
391E95.6Very high94.6Very high30 Ų3042.1 Ų42.114%0.1419%0.193CC..Hα-helixtrans-64.8-36.2174.3-75.8-63.8108.800112.3L340 S353 M356 L387 F388 K394 Y395L340-E391 HydrophobicContact CD2-CG 4.31Å; S353-E391 PolarHBondContact OG-OE2 3.05Å; M356-E391 HydrophobicContact CE-CB 3.99Å; L387-E391 PolarHBondContact O-N 3.22Å; F388-E391 PolarHBondContact O-N 3.38Å; E391-K394 WeakPolarHBondContact O-CB 3.38Å; E391-K394 PolarHBondContact O-N 2.99Å; E391-K394 WeakPolarHBondContact OE1-CD 3.49Å; E391-K394 WeakPolarHBondContact OE1-CE 3.4Å; E391-K394 IonicContact OE1-NZ 4Å; E391-K394 PolarHBondContact OE1-NZ 3.01Å; E391-K394 IonicContact OE2-NZ 2.78Å; E391-K394 PolarHBondContact OE2-NZ 3.23Å; E391-Y395 VanDerWaalsContact O-CD2 3.32Å; E391-Y395 WeakPolarHBondContact O-CD2 3.19Å; E391-Y395 PolarHBondContact O-N 3.05Å
392F97.5Very high95.2Very high0 Ų043.4 Ų43.40%020%0.199CC..Hα-helixtrans-63.1-44.5174.2-178.7-96.9000111.7M356 F388 M390 Y395 Y396 L399 I414 M421 F422M356-F392 HydrophobicContact SD-CB 4.41Å; M356-F392 HydrophobicContact SD-CD2 4.15Å; F388-F392 HydrophobicContact CE1-CB 4.37Å; F388-F392 WeakPolarHBondContact O-CB 3.47Å; F388-F392 PolarHBondContact O-N 3.06Å; M390-F392 VanDerWaalsContact C-N 3.34Å; M390-F392 PolarHBondContact O-N 2.63Å; F392-Y395 PolarHBondContact O-N 2.55Å; F392-Y396 HydrophobicContact CD1-CD2 4.26Å; F392-Y396 AromaticContact CE1-CD2 3.62Å; F392-Y396 HydrophobicContact CE1-CD2 3.62Å; F392-Y396 HydrophobicContact CE1-CE2 4.08Å; F392-Y396 HydrophobicContact CZ-CD2 4.14Å; F392-Y396 HydrophobicContact CZ-CE2 4.49Å; F392-Y396 WeakPolarHBondContact O-CA 3.48Å; F392-Y396 WeakPolarHBondContact O-CB 2.99Å; F392-Y396 PolarHBondContact O-N 2.74Å; F392-L399 HydrophobicContact CD2-CD1 3.91Å; F392-L399 HydrophobicContact CE2-CD1 3.98Å; F392-I414 HydrophobicContact CE2-CG1 4.4Å; F392-I414 WeakPolarHBondContact CE2-O 3.42Å; F392-M421 HydrophobicContact CB-CE 4.04Å; F392-M421 HydrophobicContact CB-SD 4.28Å; F392-M421 HydrophobicContact CD1-CE 3.38Å; F392-M421 HydrophobicContact CD1-SD 4.43Å; F392-M421 HydrophobicContact CD2-CE 3.9Å; F392-M421 HydrophobicContact CE1-CE 3.66Å; F392-M421 HydrophobicContact CE2-CE 4.16Å; F392-M421 HydrophobicContact CG-CE 3.51Å; F392-M421 HydrophobicContact CG-SD 4.38Å; F392-M421 HydrophobicContact CZ-CE 4.04Å; F392-F422 HydrophobicContact CD1-CE1 4.37Å; F392-F422 HydrophobicContact CD1-CZ 4.14Å; F392-F422 HydrophobicContact CE1-CE1 4.41Å; F392-F422 HydrophobicContact CE1-CE2 4.46Å; F392-F422 AromaticContact CE1-CZ 3.86Å; F392-F422 HydrophobicContact CE1-CZ 3.86Å
393V97.6Very high95.6Very high4 Ų440.4 Ų40.42%0.02418%0.184CC..Hα-helixtrans-67.2-38177.3173.20000112A389 M390 Y395 Y396 F422 L431 Q435 V437 V440A389-V393 WeakPolarHBondContact O-CG2 3.48Å; A389-V393 PolarHBondContact O-N 3.24Å; M390-V393 PolarHBondContact O-N 3.08Å; V393-Y395 VanDerWaalsContact C-N 3.28Å; V393-Y395 PolarHBondContact O-N 3.17Å; V393-Y396 WeakPolarHBondContact O-CB 3.28Å; V393-Y396 PolarHBondContact O-N 3.25Å; V393-F422 HydrophobicContact CG2-CE1 3.79Å; V393-F422 HydrophobicContact CG2-CZ 4.06Å; V393-L431 HydrophobicContact CG2-CD1 4.3Å; V393-L431 HydrophobicContact CG2-CD2 4.1Å; V393-Q435 HydrophobicContact CB-CB 4.38Å; V393-Q435 HydrophobicContact CG1-CB 3.73Å; V393-Q435 HydrophobicContact CG1-CG 4.5Å; V393-V437 HydrophobicContact CB-CG2 4.45Å; V393-V437 HydrophobicContact CG1-CB 4.07Å; V393-V437 HydrophobicContact CG1-CG2 3.88Å; V393-V437 HydrophobicContact CG2-CB 4.31Å; V393-V437 HydrophobicContact CG2-CG2 3.61Å; V393-V440 HydrophobicContact CG1-CG1 4.44Å; V393-V440 HydrophobicContact CG1-CG2 4.26Å
394K95.9Very high95.7Very high93 Ų9334.9 Ų34.940%0.40416%0.158SC..Hα-helixtrans-55.1-39.4174.7175.1-171179.3-170.60112.7M390 E391M390-K394 WeakPolarHBondContact O-CB 3.43Å; M390-K394 PolarHBondContact O-N 2.82Å; E391-K394 WeakPolarHBondContact O-CB 3.38Å; E391-K394 PolarHBondContact O-N 2.99Å; E391-K394 WeakPolarHBondContact OE1-CD 3.49Å; E391-K394 WeakPolarHBondContact OE1-CE 3.4Å; E391-K394 IonicContact OE1-NZ 4Å; E391-K394 PolarHBondContact OE1-NZ 3.01Å; E391-K394 IonicContact OE2-NZ 2.78Å; E391-K394 PolarHBondContact OE2-NZ 3.23Å
395Y96.9Very high95.5Very high45 Ų4539 Ų3918%0.17619%0.19CC..Hα-helixtrans-102.9-4.7179.5-64.5-68.1000115L357 E391 F392 V393 K397 Q398 L399L357-Y395 HydrophobicContact CD1-CD1 3.9Å; L357-Y395 HydrophobicContact CD1-CE1 3.88Å; L357-Y395 HydrophobicContact CD1-CG 4.29Å; L357-Y395 HydrophobicContact CD2-CD1 3.76Å; L357-Y395 HydrophobicContact CD2-CG 3.96Å; L357-Y395 HydrophobicContact CG-CD1 4.2Å; L357-Y395 HydrophobicContact CG-CG 4.24Å; E391-Y395 VanDerWaalsContact O-CD2 3.32Å; E391-Y395 WeakPolarHBondContact O-CD2 3.19Å; E391-Y395 PolarHBondContact O-N 3.05Å; F392-Y395 PolarHBondContact O-N 2.55Å; V393-Y395 VanDerWaalsContact C-N 3.28Å; V393-Y395 PolarHBondContact O-N 3.17Å; Y395-K397 PolarHBondContact O-N 3.36Å; Y395-Q398 WeakPolarHBondContact O-CB 3.47Å; Y395-Q398 PolarHBondContact O-N 3.5Å; Y395-L399 PolarHBondContact O-N 3.5Å; Y395-L399 VanDerWaalsContact O-N 3.14Å
396Y97.8Very high95.3Very high0 Ų039.5 Ų39.50%019%0.192CC..Hα-helixtrans-43.4-47.1-173.1-179.5-91.7000114.2F392 V393 Q398 L399 Q400 F422 V440 I441 T444 V475 D478F392-Y396 HydrophobicContact CD1-CD2 4.26Å; F392-Y396 AromaticContact CE1-CD2 3.62Å; F392-Y396 HydrophobicContact CE1-CD2 3.62Å; F392-Y396 HydrophobicContact CE1-CE2 4.08Å; F392-Y396 HydrophobicContact CZ-CD2 4.14Å; F392-Y396 HydrophobicContact CZ-CE2 4.49Å; F392-Y396 WeakPolarHBondContact O-CA 3.48Å; F392-Y396 WeakPolarHBondContact O-CB 2.99Å; F392-Y396 PolarHBondContact O-N 2.74Å; V393-Y396 WeakPolarHBondContact O-CB 3.28Å; V393-Y396 PolarHBondContact O-N 3.25Å; Y396-Q398 VanDerWaalsContact C-N 3.29Å; Y396-Q398 PolarHBondContact O-N 2.88Å; Y396-L399 PolarHBondContact O-N 2.73Å; Y396-Q400 HydrophobicContact CD1-CG 4Å; Y396-Q400 HydrophobicContact CD2-CG 4.25Å; Y396-Q400 HydrophobicContact CE1-CG 3.63Å; Y396-Q400 HydrophobicContact CE2-CG 3.92Å; Y396-Q400 HydrophobicContact CG-CG 4.29Å; Y396-Q400 VanDerWaalsContact O-CG 3.28Å; Y396-Q400 WeakPolarHBondContact O-CG 3.49Å; Y396-Q400 PolarHBondContact O-N 2.86Å; Y396-Q400 PolarHBondContact OH-NE2 2.84Å; Y396-F422 HydrophobicContact CD2-CE2 4.41Å; Y396-F422 HydrophobicContact CD2-CZ 4.17Å; Y396-F422 AromaticContact CE2-CE2 3.86Å; Y396-F422 HydrophobicContact CE2-CE2 3.86Å; Y396-F422 HydrophobicContact CE2-CZ 4.08Å; Y396-V440 HydrophobicContact CD1-CG1 4.01Å; Y396-V440 HydrophobicContact CG-CG1 4.39Å; Y396-I441 HydrophobicContact CD1-CG1 4.43Å; Y396-I441 HydrophobicContact CE1-CB 4.22Å; Y396-I441 HydrophobicContact CE1-CG1 3.76Å; Y396-I441 HydrophobicContact CE1-CG2 4.39Å; Y396-I441 HydrophobicContact CE2-CG1 4.42Å; Y396-T444 HydrophobicContact CD1-CG2 4.47Å; Y396-T444 HydrophobicContact CE1-CG2 4.2Å; Y396-V475 HydrophobicContact CE1-CG1 4.25Å; Y396-D478 WeakPolarHBondContact CE2-OD2 3.38Å; Y396-D478 VanDerWaalsContact OH-CB 3.25Å; Y396-D478 WeakPolarHBondContact OH-CB 3.47Å; Y396-D478 PolarHBondContact OH-OD2 3.36Å; Y396-D478 VanDerWaalsContact OH-OD2 3.06Å
397K96.2Very high94.8Very high77 Ų7737.5 Ų37.534%0.33519%0.185SC..Hα-helixtrans-60.3-35.6-178.4-178.2178.8-178.7174.80113.5Y395 K401 E447Y395-K397 PolarHBondContact O-N 3.36Å; K397-K401 WeakPolarHBondContact O-CG 3.45Å; K397-E447 WeakPolarHBondContact CE-OE1 3.33Å; K397-E447 WeakPolarHBondContact CE-OE2 3.41Å; K397-E447 VanDerWaalsContact NZ-CD 3.28Å; K397-E447 IonicContact NZ-OE1 3.49Å; K397-E447 PolarHBondContact NZ-OE1 3.46Å; K397-E447 IonicContact NZ-OE2 3.71Å; K397-E447 PolarHBondContact NZ-OE2 2.97Å
398Q96.5Very high94.4Very high90 Ų9034.8 Ų34.842%0.42117%0.171SC..Hα-helixtrans-76.6-50.1175.6177.6167.9-800110.1L357 Y395 Y396 Q400 K401 E402L357-Q398 HydrophobicContact CD2-CB 4.35Å; L357-Q398 VanDerWaalsContact CD2-CD 3.49Å; L357-Q398 HydrophobicContact CD2-CG 3.99Å; Y395-Q398 WeakPolarHBondContact O-CB 3.47Å; Y395-Q398 PolarHBondContact O-N 3.5Å; Y396-Q398 VanDerWaalsContact C-N 3.29Å; Y396-Q398 PolarHBondContact O-N 2.88Å; Q398-Q400 VanDerWaalsContact C-N 3.28Å; Q398-Q400 PolarHBondContact O-N 3.04Å; Q398-K401 PolarHBondContact O-N 2.73Å; Q398-E402 HydrophobicContact CG-CG 4.35Å; Q398-E402 WeakPolarHBondContact CG-OE1 3.43Å; Q398-E402 PolarHBondContact NE2-OE1 3.36Å; Q398-E402 WeakPolarHBondContact O-CG 3.31Å; Q398-E402 PolarHBondContact O-N 3.15Å
399L96.9Very high93.8Very high5 Ų539.5 Ų39.53%0.02620%0.196CC..Hα-helixtrans-53.8-42.1179.9-59.3176.9000112.6M356 L357 F392 Y395 Y396 Y403 I414 T415M356-L399 VanDerWaalsContact C-CD2 3.49Å; M356-L399 HydrophobicContact CB-CD1 4.43Å; M356-L399 HydrophobicContact CB-CD2 4.17Å; M356-L399 WeakPolarHBondContact O-CD2 3.42Å; L357-L399 HydrophobicContact CD2-CD2 4.22Å; F392-L399 HydrophobicContact CD2-CD1 3.91Å; F392-L399 HydrophobicContact CE2-CD1 3.98Å; Y395-L399 PolarHBondContact O-N 3.5Å; Y395-L399 VanDerWaalsContact O-N 3.14Å; Y396-L399 PolarHBondContact O-N 2.73Å; L399-Y403 VanDerWaalsContact O-CB 3.32Å; L399-Y403 WeakPolarHBondContact O-CB 3.46Å; L399-Y403 PolarHBondContact O-N 2.83Å; L399-I414 HydrophobicContact CD1-CG2 4.3Å; L399-I414 HydrophobicContact CD2-CG2 4.2Å; L399-T415 HydrophobicContact CB-CG2 4.24Å
400Q96Very high93.4Very high0 Ų041.6 Ų41.60%020%0.204CC..Hα-helixtrans-71.4-35.4178.4-65.2-67.3-8.100113Y396 Q398 Y403 I404 T444 V475 D478Y396-Q400 HydrophobicContact CD1-CG 4Å; Y396-Q400 HydrophobicContact CD2-CG 4.25Å; Y396-Q400 HydrophobicContact CE1-CG 3.63Å; Y396-Q400 HydrophobicContact CE2-CG 3.92Å; Y396-Q400 HydrophobicContact CG-CG 4.29Å; Y396-Q400 VanDerWaalsContact O-CG 3.28Å; Y396-Q400 WeakPolarHBondContact O-CG 3.49Å; Y396-Q400 PolarHBondContact O-N 2.86Å; Y396-Q400 PolarHBondContact OH-NE2 2.84Å; Q398-Q400 VanDerWaalsContact C-N 3.28Å; Q398-Q400 PolarHBondContact O-N 3.04Å; Q400-Y403 PolarHBondContact O-N 3.01Å; Q400-I404 WeakPolarHBondContact O-CB 3.39Å; Q400-I404 WeakPolarHBondContact O-CD1 3.45Å; Q400-I404 WeakPolarHBondContact O-CG1 3.34Å; Q400-I404 PolarHBondContact O-N 3.43Å; Q400-T444 HydrophobicContact CB-CG2 3.85Å; Q400-T444 HydrophobicContact CG-CG2 4.35Å; Q400-V475 HydrophobicContact CB-CG2 4.03Å; Q400-V475 HydrophobicContact CG-CG2 4.08Å; Q400-D478 PolarHBondContact NE2-OD2 3.14Å
401K94.8Very high92.8Very high77 Ų7740.3 Ų40.334%0.33520%0.2SC..Hα-helixtrans-68.9-39.7176.1-77.1-177.9179.9-168.70112.1K397 Q398 I404 S405 E447 V448K397-K401 WeakPolarHBondContact O-CG 3.45Å; Q398-K401 PolarHBondContact O-N 2.73Å; K401-I404 PolarHBondContact O-N 3.15Å; K401-S405 PolarHBondContact O-N 3.32Å; K401-S405 PolarHBondContact O-OG 3.08Å; K401-E447 WeakPolarHBondContact CE-OE2 3.25Å; K401-E447 IonicContact NZ-OE2 2.68Å; K401-E447 PolarHBondContact NZ-OE2 3.33Å; K401-V448 HydrophobicContact CG-CG1 4Å
402E94.7Very high92.4Very high55 Ų5540.4 Ų40.426%0.25720%0.202SC..Hα-helixtrans-62.7-51.1172.9-71.7167174.700109.4A360 Q398 I404 S405 D406A360-E402 HydrophobicContact CB-CB 3.82Å; Q398-E402 HydrophobicContact CG-CG 4.35Å; Q398-E402 WeakPolarHBondContact CG-OE1 3.43Å; Q398-E402 PolarHBondContact NE2-OE1 3.36Å; Q398-E402 WeakPolarHBondContact O-CG 3.31Å; Q398-E402 PolarHBondContact O-N 3.15Å; E402-I404 VanDerWaalsContact C-N 3.34Å; E402-I404 PolarHBondContact O-N 2.88Å; E402-S405 CarbonylContact O-C 3.53Å; E402-S405 WeakPolarHBondContact O-CA 3.31Å; E402-S405 PolarHBondContact O-N 3.47Å; E402-D406 WeakPolarHBondContact O-CB 3.25Å; E402-D406 PolarHBondContact O-N 2.93Å
403Y94.1Very high92.1Very high16 Ų1640.5 Ų40.56%0.06320%0.202CC..Hα-helixtrans-59.2-35.3175.7171.9-110.1000114.7L399 Q400 S405 D406 R410 T415 R471 A474L399-Y403 VanDerWaalsContact O-CB 3.32Å; L399-Y403 WeakPolarHBondContact O-CB 3.46Å; L399-Y403 PolarHBondContact O-N 2.83Å; Q400-Y403 PolarHBondContact O-N 3.01Å; Y403-S405 PolarHBondContact O-N 3.46Å; Y403-D406 HydrophobicContact CD2-CB 4.46Å; Y403-D406 WeakPolarHBondContact O-CB 3.36Å; Y403-D406 PolarHBondContact O-N 2.86Å; Y403-R410 HydrophobicContact CE1-CG 4.14Å; Y403-R410 HydrophobicContact CE2-CB 4.12Å; Y403-R410 HydrophobicContact CE2-CG 4.17Å; Y403-R410 WeakPolarHBondContact OH-CB 3.24Å; Y403-T415 HydrophobicContact CD1-CG2 4.44Å; Y403-T415 HydrophobicContact CG-CG2 4.07Å; Y403-R471 HydrophobicContact CE1-CB 3.91Å; Y403-R471 HydrophobicContact CE1-CG 4.17Å; Y403-R471 WeakPolarHBondContact O-CD 3.43Å; Y403-R471 PolarHBondContact O-NH1 3.49Å; Y403-A474 HydrophobicContact CD1-CB 4.48Å; Y403-A474 HydrophobicContact CE1-CB 3.83Å
404I92.6Very high91.9Very high17 Ų1740.3 Ų40.39%0.08720%0.201CC..Hα-helixtrans-68.5-20.9174.6-72.7161.1000112.2Q400 K401 E402 V448 R471 V472 V475Q400-I404 WeakPolarHBondContact O-CB 3.39Å; Q400-I404 WeakPolarHBondContact O-CD1 3.45Å; Q400-I404 WeakPolarHBondContact O-CG1 3.34Å; Q400-I404 PolarHBondContact O-N 3.43Å; K401-I404 PolarHBondContact O-N 3.15Å; E402-I404 VanDerWaalsContact C-N 3.34Å; E402-I404 PolarHBondContact O-N 2.88Å; I404-V448 HydrophobicContact CD1-CB 4.14Å; I404-V448 HydrophobicContact CD1-CG1 3.82Å; I404-V448 HydrophobicContact CD1-CG2 4.09Å; I404-R471 HydrophobicContact CB-CB 4.4Å; I404-R471 HydrophobicContact CG1-CB 3.95Å; I404-V472 HydrophobicContact CD1-CG2 3.94Å; I404-V472 HydrophobicContact CG1-CG2 4.32Å; I404-V472 HydrophobicContact CG2-CG2 4.39Å; I404-V475 HydrophobicContact CD1-CG2 4.17Å
405S89.9Confident91.9Very high103 Ų10336 Ų3672%0.7218%0.182SC*.Hα-helixtrans-103.3-10.2178.3-45.70000113.6K401 E402 Y403K401-S405 PolarHBondContact O-N 3.32Å; K401-S405 PolarHBondContact O-OG 3.08Å; E402-S405 CarbonylContact O-C 3.53Å; E402-S405 WeakPolarHBondContact O-CA 3.31Å; E402-S405 PolarHBondContact O-N 3.47Å; Y403-S405 PolarHBondContact O-N 3.46Å
406D89.4Confident91.7Very high14 Ų1434.4 Ų34.48%0.07518%0.179CC..  trans-67.6160.7176.6-171.43.3000110.6A360 R367 E402 Y403 H408 R471A360-D406 HydrophobicContact CB-CB 4.35Å; R367-D406 IonicContact CZ-OD1 3.45Å; R367-D406 IonicContact CZ-OD2 2.76Å; R367-D406 IonicContact NH1-OD1 3.44Å; R367-D406 IonicContact NH1-OD2 3.46Å; R367-D406 PolarHBondContact NH1-OD2 3.37Å; R367-D406 IonicContact NH2-OD1 3.3Å; R367-D406 PolarHBondContact NH2-OD1 3.35Å; R367-D406 IonicContact NH2-OD2 3.76Å; R367-D406 PolarHBondContact NH2-OD2 3.4Å; E402-D406 WeakPolarHBondContact O-CB 3.25Å; E402-D406 PolarHBondContact O-N 2.93Å; Y403-D406 HydrophobicContact CD2-CB 4.46Å; Y403-D406 WeakPolarHBondContact O-CB 3.36Å; Y403-D406 PolarHBondContact O-N 2.86Å; D406-H408 IonicContact OD1-CG 3.01Å; D406-H408 PolarHBondContact OD1-N 3.31Å; D406-H408 IonicContact OD1-ND1 3.98Å; D406-R471 PolarHBondContact O-NE 2.98Å; D406-R471 PolarHBondContact O-NH1 2.91Å; D406-R471 PolarHBondContact O-NH2 3Å
407D84Confident91.4Very high42 Ų4234.4 Ų34.423%0.22518%0.179CC..  trans-100.6-27.8172.260-12.9000112D233 H235 R471D233-D407 WeakPolarHBondContact CA-OD2 3.21Å; D233-D407 WeakPolarHBondContact CB-OD2 3.31Å; H235-D407 WeakPolarHBondContact CE1-CB 3.2Å; H235-D407 WeakPolarHBondContact ND1-CB 3.15Å; D407-R471 PolarHBondContact O-NH2 2.92Å
408H86.8Confident91.4Very high10 Ų1030.8 Ų30.85%0.04616%0.163CC..SBendtrans-69.7158-176.4-72.965.7000113.6R367 D406 I412 R471R367-H408 PolarHBondContact NH2-ND1 2.75Å; D406-H408 IonicContact OD1-CG 3.01Å; D406-H408 PolarHBondContact OD1-N 3.31Å; D406-H408 IonicContact OD1-ND1 3.98Å; H408-I412 HydrophobicContact CB-CD1 4.13Å; H408-I412 HydrophobicContact CB-CG1 4.46Å; H408-R471 PolarHBondContact O-NH1 3.23Å; H408-R471 PolarHBondContact O-NH2 3.27Å
409D83.9Confident91.1Very high98 Ų9827.5 Ų27.552%0.52415%0.149SC..  trans-70.1145.2-178.1-145.36.6000112.4S411 I412D409-S411 PolarHBondContact O-N 3.21Å; D409-S411 VanDerWaalsContact O-N 3.15Å; D409-I412 HydrophobicContact CB-CG1 4.34Å; D409-I412 WeakPolarHBondContact O-CG1 3.47Å; D409-I412 PolarHBondContact O-N 3.13Å
410R87.6Confident90.8Very high44 Ų4428.3 Ų28.317%0.16615%0.153CC..G310 helixtrans-58.8-36.5-175.3-159.8-171.4169178.41.4112.4Y403 I412 S413 T415 A416 S418 A474 D478Y403-R410 HydrophobicContact CE1-CG 4.14Å; Y403-R410 HydrophobicContact CE2-CB 4.12Å; Y403-R410 HydrophobicContact CE2-CG 4.17Å; Y403-R410 WeakPolarHBondContact OH-CB 3.24Å; R410-I412 PolarHBondContact O-N 3.49Å; R410-S413 PolarHBondContact O-N 2.84Å; R410-T415 PolarHBondContact NH2-O 3.37Å; R410-A416 HydrophobicContact CG-CB 4.3Å; R410-A416 WeakPolarHBondContact O-CB 3.32Å; R410-S418 PolarHBondContact NH2-OG 3.45Å; R410-S418 VanDerWaalsContact NH2-OG 3.08Å; R410-A474 PolarHBondContact NH1-O 3.16Å; R410-D478 IonicContact CZ-OD1 3.82Å; R410-D478 IonicContact NH1-OD1 3.3Å; R410-D478 IonicContact NH2-OD1 2.67Å; R410-D478 PolarHBondContact NH2-OD1 3.21Å; R410-D478 IonicContact NH2-OD2 3.35Å; R410-D478 PolarHBondContact NH2-OD2 3.2Å
411S84.9Confident90.7Very high26 Ų2628.3 Ų28.318%0.18215%0.153CC..G310 helixtrans-57.6-22.3-17461.20000114.3H371 D409H371-S411 PolarHBondContact CE1-O 2.91Å; H371-S411 VanDerWaalsContact CE1-O 3.25Å; D409-S411 PolarHBondContact O-N 3.21Å; D409-S411 VanDerWaalsContact O-N 3.15Å
412I86.1Confident90.7Very high33 Ų3324.7 Ų24.717%0.16914%0.137CC..G310 helixtrans-112.91.9178.956.9174000113.1K364 R367 H371 H408 D409 R410K364-I412 HydrophobicContact CB-CD1 4.46Å; K364-I412 HydrophobicContact CD-CD1 4.15Å; K364-I412 HydrophobicContact CG-CD1 3.79Å; R367-I412 VanDerWaalsContact CB-O 3.31Å; R367-I412 WeakPolarHBondContact CB-O 3.32Å; R367-I412 WeakPolarHBondContact CD-O 3.35Å; H371-I412 VanDerWaalsContact CE1-C 3.46Å; H371-I412 PolarHBondContact NE2-O 3.15Å; H408-I412 HydrophobicContact CB-CD1 4.13Å; H408-I412 HydrophobicContact CB-CG1 4.46Å; D409-I412 HydrophobicContact CB-CG1 4.34Å; D409-I412 WeakPolarHBondContact O-CG1 3.47Å; D409-I412 PolarHBondContact O-N 3.13Å; R410-I412 PolarHBondContact O-N 3.49Å
413S91.9Very high90.6Very high1 Ų122.7 Ų22.71%0.00713%0.129CC..SBendtrans-88.9145.7170.7174.50000111.2D359 H371 R410 T415 A416D359-S413 WeakPolarHBondContact OD2-CA 3.46Å; D359-S413 WeakPolarHBondContact OD2-CB 3.47Å; D359-S413 PolarHBondContact OD2-OG 3.48Å; H371-S413 PolarHBondContact CE1-O 3.07Å; H371-S413 WeakPolarHBondContact NE2-CA 3.46Å; H371-S413 PolarHBondContact NE2-N 3.33Å; H371-S413 PolarHBondContact NE2-O 3.21Å; R410-S413 PolarHBondContact O-N 2.84Å; S413-T415 PolarHBondContact O-N 3.16Å; S413-T415 PolarHBondContact OG-N 2.99Å; S413-T415 PolarHBondContact OG-OG1 3.35Å; S413-A416 WeakPolarHBondContact O-CB 3.4Å; S413-A416 PolarHBondContact O-N 3.09Å
414I94Very high90.4Very high1 Ų122.5 Ų22.51%0.00513%0.129CC..G310 helixtrans-50.4-28.6170.5-160.576.7000112.5M356 D359 L370 H371 I374 F388 F392 L399 A416 L417M356-I414 HydrophobicContact CB-CG1 4.29Å; M356-I414 HydrophobicContact CG-CD1 3.92Å; M356-I414 HydrophobicContact CG-CG1 3.85Å; M356-I414 HydrophobicContact SD-CD1 4.46Å; M356-I414 HydrophobicContact SD-CG1 4.2Å; D359-I414 HydrophobicContact CB-CB 3.96Å; D359-I414 HydrophobicContact CB-CG2 3.65Å; D359-I414 PolarHBondContact OD1-N 2.69Å; D359-I414 PolarHBondContact OD2-N 2.93Å; L370-I414 HydrophobicContact CD2-CD1 4.21Å; L370-I414 HydrophobicContact CG-CD1 4.4Å; H371-I414 WeakPolarHBondContact NE2-CA 3.32Å; H371-I414 PolarHBondContact NE2-N 2.79Å; I374-I414 HydrophobicContact CD1-CD1 3.43Å; I374-I414 VanDerWaalsContact CD1-CD1 3.43Å; F388-I414 HydrophobicContact CZ-CD1 4.32Å; F392-I414 HydrophobicContact CE2-CG1 4.4Å; F392-I414 WeakPolarHBondContact CE2-O 3.42Å; L399-I414 HydrophobicContact CD1-CG2 4.3Å; L399-I414 HydrophobicContact CD2-CG2 4.2Å; I414-A416 PolarHBondContact O-N 2.98Å; I414-L417 HydrophobicContact CD1-CD1 3.67Å; I414-L417 HydrophobicContact CG1-CD1 4.4Å; I414-L417 WeakPolarHBondContact O-CB 3.3Å; I414-L417 WeakPolarHBondContact O-CG 3.32Å; I414-L417 PolarHBondContact O-N 3.47Å
415T94.7Very high90.3Very high1 Ų122.7 Ų22.71%0.00613%0.131CC..G310 helixtrans-66.9-17.4178.263.50000114.2L399 Y403 R410 S413 L417 S418L399-T415 HydrophobicContact CB-CG2 4.24Å; Y403-T415 HydrophobicContact CD1-CG2 4.44Å; Y403-T415 HydrophobicContact CG-CG2 4.07Å; R410-T415 PolarHBondContact NH2-O 3.37Å; S413-T415 PolarHBondContact O-N 3.16Å; S413-T415 PolarHBondContact OG-N 2.99Å; S413-T415 PolarHBondContact OG-OG1 3.35Å; T415-L417 VanDerWaalsContact C-N 3.3Å; T415-S418 PolarHBondContact O-OG 2.89Å
416A92.4Very high90.4Very high13 Ų1320.7 Ų20.711%0.10712%0.115CC..G310 helixtrans-71.9-22.5170.200000113.1R410 S413 I414 S418 V419R410-A416 HydrophobicContact CG-CB 4.3Å; R410-A416 WeakPolarHBondContact O-CB 3.32Å; S413-A416 WeakPolarHBondContact O-CB 3.4Å; S413-A416 PolarHBondContact O-N 3.09Å; I414-A416 PolarHBondContact O-N 2.98Å; A416-S418 PolarHBondContact O-N 2.81Å; A416-S418 VanDerWaalsContact O-N 3.16Å; A416-V419 WeakPolarHBondContact O-CG1 3.34Å; A416-V419 PolarHBondContact O-N 3.42Å
417L93Very high90.5Very high0 Ų020.4 Ų20.40%011%0.114CC..G310 helixtrans-69.3-12.2-177.7-56.3-170.8000113.3I374 F375 F379 F388 I414 T415 V419 Q420 M421I374-L417 HydrophobicContact CB-CD1 4.4Å; I374-L417 HydrophobicContact CD1-CD1 3.82Å; I374-L417 HydrophobicContact CG2-CD1 3.94Å; F375-L417 HydrophobicContact CE1-CD2 4.21Å; F375-L417 HydrophobicContact CE2-CD2 3.8Å; F375-L417 HydrophobicContact CZ-CD2 3.41Å; F375-L417 VanDerWaalsContact CZ-CD2 3.41Å; F379-L417 HydrophobicContact CE2-CB 4.34Å; F379-L417 HydrophobicContact CE2-CD1 4.42Å; F379-L417 HydrophobicContact CE2-CD2 4.34Å; F379-L417 HydrophobicContact CZ-CB 4.17Å; F379-L417 HydrophobicContact CZ-CD1 4.34Å; F388-L417 HydrophobicContact CE1-CD1 4.47Å; F388-L417 HydrophobicContact CZ-CD1 4.23Å; I414-L417 HydrophobicContact CD1-CD1 3.67Å; I414-L417 HydrophobicContact CG1-CD1 4.4Å; I414-L417 WeakPolarHBondContact O-CB 3.3Å; I414-L417 WeakPolarHBondContact O-CG 3.32Å; I414-L417 PolarHBondContact O-N 3.47Å; T415-L417 VanDerWaalsContact C-N 3.3Å; L417-V419 PolarHBondContact O-N 3.01Å; L417-Q420 WeakPolarHBondContact O-CB 3.27Å; L417-Q420 PolarHBondContact O-N 3.26Å; L417-M421 HydrophobicContact CB-CE 4.22Å; L417-M421 WeakPolarHBondContact O-CE 3.22Å
418S94.8Very high91Very high0 Ų018.5 Ų18.50%010%0.103CC..G310 helixtrans-50.6-38.7174.462.60000112.7R410 T415 A416 Q420 M421 F422 D478R410-S418 PolarHBondContact NH2-OG 3.45Å; R410-S418 VanDerWaalsContact NH2-OG 3.08Å; T415-S418 PolarHBondContact O-OG 2.89Å; A416-S418 PolarHBondContact O-N 2.81Å; A416-S418 VanDerWaalsContact O-N 3.16Å; S418-Q420 PolarHBondContact O-N 3.45Å; S418-M421 PolarHBondContact O-N 3.43Å; S418-M421 VanDerWaalsContact O-N 3.1Å; S418-F422 WeakPolarHBondContact O-CB 3.49Å; S418-F422 PolarHBondContact O-N 3.07Å; S418-D478 WeakPolarHBondContact CB-OD1 3.48Å; S418-D478 VanDerWaalsContact CB-OD2 3.31Å; S418-D478 WeakPolarHBondContact CB-OD2 3.39Å; S418-D478 PolarHBondContact OG-OD1 3.42Å; S418-D478 PolarHBondContact OG-OD2 3.03Å
419V91.6Very high91.3Very high22 Ų2221.9 Ų21.913%0.13312%0.116CC..G310 helixtrans-64.1-21.6178.776.10000113.1T120 A416 L417 T423 Y481T120-V419 HydrophobicContact CG2-CG2 3.73Å; A416-V419 WeakPolarHBondContact O-CG1 3.34Å; A416-V419 PolarHBondContact O-N 3.42Å; L417-V419 PolarHBondContact O-N 3.01Å; V419-T423 HydrophobicContact CG2-CG2 3.91Å; V419-T423 WeakPolarHBondContact O-CB 3.46Å; V419-T423 WeakPolarHBondContact O-CG2 3.19Å; V419-T423 PolarHBondContact O-OG1 2.99Å; V419-Y481 HydrophobicContact CB-CD2 4.1Å; V419-Y481 HydrophobicContact CB-CE2 3.69Å; V419-Y481 HydrophobicContact CG2-CD1 4.15Å; V419-Y481 HydrophobicContact CG2-CD2 4.2Å; V419-Y481 HydrophobicContact CG2-CE1 3.71Å; V419-Y481 HydrophobicContact CG2-CE2 3.78Å; V419-Y481 HydrophobicContact CG2-CG 4.4Å
420Q89.6Confident91.7Very high22 Ų2219.5 Ų19.510%0.10310%0.101CC..G310 helixtrans-89.4-4.4179.8-54.5-61.2-23.400112.9F148 F375 F379 L417 S418 V424F148-Q420 HydrophobicContact CE1-CB 4.43Å; F148-Q420 HydrophobicContact CE1-CG 4.21Å; F375-Q420 HydrophobicContact CE1-CG 4.11Å; F379-Q420 HydrophobicContact CD2-CB 3.97Å; F379-Q420 HydrophobicContact CD2-CG 4.38Å; F379-Q420 HydrophobicContact CE2-CB 3.4Å; F379-Q420 HydrophobicContact CE2-CG 3.85Å; F379-Q420 HydrophobicContact CZ-CB 3.92Å; L417-Q420 WeakPolarHBondContact O-CB 3.27Å; L417-Q420 PolarHBondContact O-N 3.26Å; S418-Q420 PolarHBondContact O-N 3.45Å; Q420-V424 WeakPolarHBondContact O-CG2 3.42Å
421M93.4Very high92.1Very high0 Ų017.4 Ų17.40%09%0.093CC..THydrogen-bonded Turntrans-125.4-41.6-174.9-62.6-179.6-74.800112.7F379 F388 A389 F392 L417 S418 L427F379-M421 HydrophobicContact CE1-CG 4.08Å; F379-M421 HydrophobicContact CE1-SD 4.22Å; F379-M421 HydrophobicContact CZ-CG 4.01Å; F379-M421 HydrophobicContact CZ-SD 4.23Å; F388-M421 HydrophobicContact CD1-CE 4.43Å; F388-M421 HydrophobicContact CD1-SD 3.53Å; F388-M421 VanDerWaalsContact CD1-SD 3.53Å; F388-M421 HydrophobicContact CE1-CE 3.96Å; F388-M421 HydrophobicContact CE1-SD 3.65Å; A389-M421 VanDerWaalsContact CA-SD 3.53Å; A389-M421 HydrophobicContact CB-CB 4.18Å; A389-M421 HydrophobicContact CB-CG 4.05Å; A389-M421 HydrophobicContact CB-SD 3.53Å; A389-M421 VanDerWaalsContact CB-SD 3.53Å; F392-M421 HydrophobicContact CB-CE 4.04Å; F392-M421 HydrophobicContact CB-SD 4.28Å; F392-M421 HydrophobicContact CD1-CE 3.38Å; F392-M421 HydrophobicContact CD1-SD 4.43Å; F392-M421 HydrophobicContact CD2-CE 3.9Å; F392-M421 HydrophobicContact CE1-CE 3.66Å; F392-M421 HydrophobicContact CE2-CE 4.16Å; F392-M421 HydrophobicContact CG-CE 3.51Å; F392-M421 HydrophobicContact CG-SD 4.38Å; F392-M421 HydrophobicContact CZ-CE 4.04Å; L417-M421 HydrophobicContact CB-CE 4.22Å; L417-M421 WeakPolarHBondContact O-CE 3.22Å; S418-M421 PolarHBondContact O-N 3.43Å; S418-M421 VanDerWaalsContact O-N 3.1Å; M421-L427 HydrophobicContact CB-CD2 4.16Å; M421-L427 HydrophobicContact CG-CD2 4.5Å
422F95Very high92.6Very high0 Ų016.1 Ų16.10%09%0.085CC..SBendtrans-84.5-18.3-174.7-63.4-8000113.2F392 V393 Y396 S418 A428 L431 V437 I441 D478 Y481 I482F392-F422 HydrophobicContact CD1-CE1 4.37Å; F392-F422 HydrophobicContact CD1-CZ 4.14Å; F392-F422 HydrophobicContact CE1-CE1 4.41Å; F392-F422 HydrophobicContact CE1-CE2 4.46Å; F392-F422 AromaticContact CE1-CZ 3.86Å; F392-F422 HydrophobicContact CE1-CZ 3.86Å; V393-F422 HydrophobicContact CG2-CE1 3.79Å; V393-F422 HydrophobicContact CG2-CZ 4.06Å; Y396-F422 HydrophobicContact CD2-CE2 4.41Å; Y396-F422 HydrophobicContact CD2-CZ 4.17Å; Y396-F422 AromaticContact CE2-CE2 3.86Å; Y396-F422 HydrophobicContact CE2-CE2 3.86Å; Y396-F422 HydrophobicContact CE2-CZ 4.08Å; S418-F422 WeakPolarHBondContact O-CB 3.49Å; S418-F422 PolarHBondContact O-N 3.07Å; F422-A428 WeakPolarHBondContact O-CB 3.27Å; F422-L431 HydrophobicContact CD1-CD1 3.84Å; F422-L431 HydrophobicContact CE1-CD1 3.9Å; F422-V437 HydrophobicContact CE1-CG2 4.04Å; F422-V437 HydrophobicContact CZ-CG2 3.91Å; F422-I441 HydrophobicContact CD2-CD1 4.22Å; F422-I441 HydrophobicContact CE2-CD1 3.82Å; F422-I441 HydrophobicContact CE2-CG1 4.46Å; F422-I441 HydrophobicContact CZ-CD1 4.46Å; F422-D478 HydrophobicContact CD2-CB 4.08Å; F422-D478 HydrophobicContact CE2-CB 4.05Å; F422-Y481 CarbonylContact O-C 3.44Å; F422-Y481 VanDerWaalsContact O-O 3.09Å; F422-I482 HydrophobicContact CB-CB 4.21Å; F422-I482 HydrophobicContact CB-CD1 3.87Å; F422-I482 HydrophobicContact CD1-CD1 3.95Å; F422-I482 HydrophobicContact CG-CD1 3.94Å; F422-I482 WeakPolarHBondContact O-CA 3.27Å
423T92.1Very high93Very high13 Ų1316.8 Ų16.88%0.089%0.087CC..SBendtrans-79.3-38.5174.356.30000111.6T120 V419 P425 Y481 I484 S485T120-T423 HydrophobicContact CG2-CG2 4.26Å; T120-T423 WeakPolarHBondContact OG1-CG2 3.33Å; V419-T423 HydrophobicContact CG2-CG2 3.91Å; V419-T423 WeakPolarHBondContact O-CB 3.46Å; V419-T423 WeakPolarHBondContact O-CG2 3.19Å; V419-T423 PolarHBondContact O-OG1 2.99Å; T423-P425 VanDerWaalsContact O-CD 3.23Å; T423-P425 WeakPolarHBondContact O-CD 3.33Å; T423-P425 VanDerWaalsContact O-N 3.12Å; T423-Y481 HydrophobicContact CG2-CD1 3.95Å; T423-Y481 HydrophobicContact CG2-CG 4.12Å; T423-I484 HydrophobicContact CG2-CD1 4.25Å; T423-S485 PolarHBondContact O-OG 3.2Å
424V91.1Very high93Very high12 Ų1220.2 Ų20.27%0.07310%0.103CC..SBendtrans-55.6109.8-176.6178.80000110.6M382 Q420 T426 L427 A428M382-V424 HydrophobicContact CE-CG1 4.17Å; Q420-V424 WeakPolarHBondContact O-CG2 3.42Å; V424-T426 PolarHBondContact O-N 3.01Å; V424-L427 HydrophobicContact CB-CB 4.01Å; V424-L427 HydrophobicContact CG1-CB 3.84Å; V424-L427 PolarHBondContact O-N 3.49Å; V424-A428 WeakPolarHBondContact O-CB 3.4Å; V424-A428 PolarHBondContact O-N 3.24Å
425P90.3Very high93.1Very high21 Ų2123.1 Ų23.114%0.13612%0.116CC..Hα-helixtrans-53.2-45.8-168.5-26.727.9000116.2I117 E155 T423 R429 S485I117-P425 HydrophobicContact CG2-CG 4.46Å; E155-P425 HydrophobicContact CB-CG 4.23Å; E155-P425 WeakPolarHBondContact OE2-CD 3.28Å; T423-P425 VanDerWaalsContact O-CD 3.23Å; T423-P425 WeakPolarHBondContact O-CD 3.33Å; T423-P425 VanDerWaalsContact O-N 3.12Å; P425-R429 VanDerWaalsContact C-NH2 3.32Å; P425-R429 PolarHBondContact O-N 3.5Å; P425-R429 PolarHBondContact O-NE 3.5Å; P425-R429 PolarHBondContact O-NH2 2.84Å; P425-S485 WeakPolarHBondContact CG-OG 3.37Å
426T91Very high93.1Very high61 Ų6124.4 Ų24.437%0.37412%0.123SC..Hα-helixtrans-71.2-41.6-18058.30000112E155 V424 H430E155-T426 VanDerWaalsContact CD-OG1 3.25Å; E155-T426 WeakPolarHBondContact OE1-CB 3.46Å; E155-T426 WeakPolarHBondContact OE1-CG2 3.25Å; E155-T426 PolarHBondContact OE1-OG1 2.91Å; E155-T426 WeakPolarHBondContact OE2-CB 3.35Å; E155-T426 VanDerWaalsContact OE2-CG2 3.26Å; E155-T426 WeakPolarHBondContact OE2-CG2 3.39Å; E155-T426 PolarHBondContact OE2-N 3.48Å; E155-T426 PolarHBondContact OE2-OG1 3.31Å; E155-T426 VanDerWaalsContact OE2-OG1 3.1Å; V424-T426 PolarHBondContact O-N 3.01Å; T426-H430 PolarHBondContact O-N 2.93Å; T426-H430 VanDerWaalsContact O-N 3.08Å
427L93.4Very high93.4Very high9 Ų923.8 Ų23.85%0.04712%0.118CC..Hα-helixtrans-69.3-44.8-178.3-177.454.8000111.4K385 K386 A389 M421 V424 R429 H430 L431K385-L427 HydrophobicContact CD-CD2 4.37Å; K385-L427 HydrophobicContact CG-CD2 4.12Å; K386-L427 HydrophobicContact CB-CD1 4.06Å; K386-L427 HydrophobicContact CG-CD1 3.94Å; A389-L427 HydrophobicContact CB-CD1 4.07Å; A389-L427 HydrophobicContact CB-CD2 3.9Å; A389-L427 HydrophobicContact CB-CG 4.3Å; M421-L427 HydrophobicContact CB-CD2 4.16Å; M421-L427 HydrophobicContact CG-CD2 4.5Å; V424-L427 HydrophobicContact CB-CB 4.01Å; V424-L427 HydrophobicContact CG1-CB 3.84Å; V424-L427 PolarHBondContact O-N 3.49Å; L427-R429 VanDerWaalsContact C-N 3.34Å; L427-R429 PolarHBondContact O-N 3.29Å; L427-H430 CarbonylContact O-C 3.6Å; L427-H430 WeakPolarHBondContact O-CA 3.47Å; L427-H430 WeakPolarHBondContact O-CB 3.33Å; L427-H430 PolarHBondContact O-N 3.3Å; L427-L431 HydrophobicContact CD1-CD1 4.28Å; L427-L431 HydrophobicContact CD1-CD2 4.41Å; L427-L431 HydrophobicContact CD1-CG 4.09Å; L427-L431 HydrophobicContact CG-CD1 4.06Å; L427-L431 HydrophobicContact CG-CG 4.34Å; L427-L431 WeakPolarHBondContact O-CG 3.46Å; L427-L431 PolarHBondContact O-N 3.25Å
428A93.9Very high93.6Very high1 Ų123.8 Ų23.81%0.00812%0.118CC..Hα-helixtrans-53.9-49.6175.500000111.8F422 V424 H430 L431 I432 I482F422-A428 WeakPolarHBondContact O-CB 3.27Å; V424-A428 WeakPolarHBondContact O-CB 3.4Å; V424-A428 PolarHBondContact O-N 3.24Å; A428-H430 VanDerWaalsContact C-N 3.34Å; A428-H430 PolarHBondContact O-N 3.32Å; A428-L431 PolarHBondContact O-N 3.23Å; A428-I432 VanDerWaalsContact O-CG1 3.29Å; A428-I432 WeakPolarHBondContact O-CG1 3.19Å; A428-I432 PolarHBondContact O-N 3.49Å; A428-I482 HydrophobicContact CB-CD1 3.76Å
429R91.9Very high93.7Very high82 Ų8223.9 Ų23.931%0.30912%0.119SC..Hα-helixtrans-59.3-42.6175.2-77.3175.1-76.2145.8-5.9112.3P425 L427 I432 E433P425-R429 VanDerWaalsContact C-NH2 3.32Å; P425-R429 PolarHBondContact O-N 3.5Å; P425-R429 PolarHBondContact O-NE 3.5Å; P425-R429 PolarHBondContact O-NH2 2.84Å; L427-R429 VanDerWaalsContact C-N 3.34Å; L427-R429 PolarHBondContact O-N 3.29Å; R429-I432 PolarHBondContact O-N 2.85Å; R429-E433 WeakPolarHBondContact O-CB 3.34Å; R429-E433 PolarHBondContact O-N 2.91Å
430H93.3Very high94Very high47 Ų4724.6 Ų24.622%0.21812%0.123CC..Hα-helixtrans-63.8-41.2177.1-17470.1000112.8K386 T426 L427 A428 E433 E434K386-H430 WeakPolarHBondContact CE-CD2 3.42Å; K386-H430 VanDerWaalsContact CE-CE1 3.46Å; K386-H430 WeakPolarHBondContact CE-CE1 3.48Å; K386-H430 WeakPolarHBondContact CE-NE2 3.36Å; T426-H430 PolarHBondContact O-N 2.93Å; T426-H430 VanDerWaalsContact O-N 3.08Å; L427-H430 CarbonylContact O-C 3.6Å; L427-H430 WeakPolarHBondContact O-CA 3.47Å; L427-H430 WeakPolarHBondContact O-CB 3.33Å; L427-H430 PolarHBondContact O-N 3.3Å; A428-H430 VanDerWaalsContact C-N 3.34Å; A428-H430 PolarHBondContact O-N 3.32Å; H430-E433 PolarHBondContact O-N 2.98Å; H430-E434 WeakPolarHBondContact CE1-CG 3.48Å; H430-E434 WeakPolarHBondContact O-CB 3.23Å; H430-E434 PolarHBondContact O-N 2.6Å
431L96Very high94.4Very high0 Ų023.5 Ų23.50%012%0.118CC..Hα-helixtrans-68.8-31.9177.8-65.2171.8000112.4A389 M390 V393 F422 L427 A428 Q435 N436 V437A389-L431 HydrophobicContact CB-CD1 4.13Å; A389-L431 HydrophobicContact CB-CD2 4.14Å; M390-L431 HydrophobicContact CG-CD2 4.31Å; V393-L431 HydrophobicContact CG2-CD1 4.3Å; V393-L431 HydrophobicContact CG2-CD2 4.1Å; F422-L431 HydrophobicContact CD1-CD1 3.84Å; F422-L431 HydrophobicContact CE1-CD1 3.9Å; L427-L431 HydrophobicContact CD1-CD1 4.28Å; L427-L431 HydrophobicContact CD1-CD2 4.41Å; L427-L431 HydrophobicContact CD1-CG 4.09Å; L427-L431 HydrophobicContact CG-CD1 4.06Å; L427-L431 HydrophobicContact CG-CG 4.34Å; L427-L431 WeakPolarHBondContact O-CG 3.46Å; L427-L431 PolarHBondContact O-N 3.25Å; A428-L431 PolarHBondContact O-N 3.23Å; L431-Q435 HydrophobicContact CD2-CG 4.2Å; L431-Q435 CarbonylContact O-C 3.34Å; L431-Q435 WeakPolarHBondContact O-CA 3.19Å; L431-Q435 WeakPolarHBondContact O-CB 3.46Å; L431-Q435 PolarHBondContact O-N 2.87Å; L431-N436 PolarHBondContact O-N 3.45Å; L431-N436 VanDerWaalsContact O-N 3.16Å; L431-V437 HydrophobicContact CB-CB 4.13Å; L431-V437 HydrophobicContact CB-CG1 3.77Å; L431-V437 PolarHBondContact O-N 2.84Å
432I95.1Very high94.6Very high0 Ų023.5 Ų23.50%012%0.118CC..Hα-helixtrans-68.3-47.9172.1-59.8162.1000110A428 R429 N436 V437 I438 I482 L494 Q497 W552A428-I432 VanDerWaalsContact O-CG1 3.29Å; A428-I432 WeakPolarHBondContact O-CG1 3.19Å; A428-I432 PolarHBondContact O-N 3.49Å; R429-I432 PolarHBondContact O-N 2.85Å; I432-N436 WeakPolarHBondContact O-CA 3.41Å; I432-N436 PolarHBondContact O-N 3.01Å; I432-V437 HydrophobicContact CG1-CG1 3.79Å; I432-I438 HydrophobicContact CD1-CD1 3.91Å; I432-I438 HydrophobicContact CD1-CG1 4.44Å; I432-I438 HydrophobicContact CG1-CD1 3.94Å; I432-I438 HydrophobicContact CG1-CG1 4.06Å; I432-I438 HydrophobicContact CG2-CD1 4.02Å; I432-I482 HydrophobicContact CD1-CG1 4.1Å; I432-I482 HydrophobicContact CG1-CD1 4.49Å; I432-I482 HydrophobicContact CG1-CG1 3.99Å; I432-L494 HydrophobicContact CB-CD1 3.91Å; I432-L494 HydrophobicContact CG2-CD1 3.62Å; I432-Q497 HydrophobicContact CG2-CB 4.27Å; I432-Q497 VanDerWaalsContact O-CB 3.28Å; I432-Q497 WeakPolarHBondContact O-CB 3.22Å; I432-Q497 WeakPolarHBondContact O-CG 3.46Å; I432-W552 HydrophobicContact CD1-CH2 3.43Å; I432-W552 VanDerWaalsContact CD1-CH2 3.43Å; I432-W552 HydrophobicContact CD1-CZ2 4.47Å; I432-W552 HydrophobicContact CD1-CZ3 3.85Å
433E93.8Very high94.7Very high46 Ų4627.1 Ų27.122%0.21514%0.135CC..Hα-helixtrans-70.2-43.4-175.6-172.6164.6-15000112.9R429 H430 T491 R493 L494R429-E433 WeakPolarHBondContact O-CB 3.34Å; R429-E433 PolarHBondContact O-N 2.91Å; H430-E433 PolarHBondContact O-N 2.98Å; E433-T491 WeakPolarHBondContact OE1-CB 3.27Å; E433-T491 PolarHBondContact OE1-OG1 3.13Å; E433-R493 HydrophobicContact CG-CB 4.04Å; E433-R493 HydrophobicContact CG-CG 3.82Å; E433-R493 PolarHBondContact O-NE 2.87Å; E433-R493 PolarHBondContact O-NH2 2.96Å; E433-L494 HydrophobicContact CB-CD1 4.37Å
434E93.3Very high94.9Very high74 Ų7426.5 Ų26.535%0.34613%0.131SC..Hα-helixtrans-93-35.2-176.2-64.8-54.4137.500115H430 R493H430-E434 WeakPolarHBondContact CE1-CG 3.48Å; H430-E434 WeakPolarHBondContact O-CB 3.23Å; H430-E434 PolarHBondContact O-N 2.6Å; E434-R493 VanDerWaalsContact CD-CZ 3.4Å; E434-R493 IonicContact OE1-CZ 3.93Å; E434-R493 IonicContact OE1-NE 3.66Å; E434-R493 IonicContact OE1-NH1 3.69Å; E434-R493 PolarHBondContact OE1-NH1 3.08Å; E434-R493 IonicContact OE1-NH2 2.77Å; E434-R493 IonicContact OE2-CZ 2.73Å; E434-R493 IonicContact OE2-NH1 2.65Å; E434-R493 PolarHBondContact OE2-NH1 3.45Å; E434-R493 IonicContact OE2-NH2 3.43Å; E434-R493 PolarHBondContact OE2-NH2 3.12Å
435Q95.4Very high95.1Very high61 Ų6126 Ų2629%0.28513%0.128SC..Hα-helixtrans-114.43.6-171.3-59.1-63.3-41.900114M390 V393 L431 V437M390-Q435 HydrophobicContact CG-CG 4.32Å; V393-Q435 HydrophobicContact CB-CB 4.38Å; V393-Q435 HydrophobicContact CG1-CB 3.73Å; V393-Q435 HydrophobicContact CG1-CG 4.5Å; L431-Q435 HydrophobicContact CD2-CG 4.2Å; L431-Q435 CarbonylContact O-C 3.34Å; L431-Q435 WeakPolarHBondContact O-CA 3.19Å; L431-Q435 WeakPolarHBondContact O-CB 3.46Å; L431-Q435 PolarHBondContact O-N 2.87Å; Q435-V437 PolarHBondContact O-N 3.38Å; Q435-V437 VanDerWaalsContact O-N 3.13Å
436N95.8Very high95.2Very high28 Ų2827.1 Ų27.115%0.1513%0.133CC..  trans50.736.1-178.6-159.70.4000113.6L431 I432 I438 S439 V440 Q497 E500L431-N436 PolarHBondContact O-N 3.45Å; L431-N436 VanDerWaalsContact O-N 3.16Å; I432-N436 WeakPolarHBondContact O-CA 3.41Å; I432-N436 PolarHBondContact O-N 3.01Å; N436-I438 PolarHBondContact O-N 2.66Å; N436-S439 VanDerWaalsContact CG-CB 3.46Å; N436-S439 VanDerWaalsContact CG-OG 3.23Å; N436-S439 WeakPolarHBondContact ND2-CB 3.45Å; N436-S439 PolarHBondContact ND2-OG 3.33Å; N436-S439 WeakPolarHBondContact O-CA 3.2Å; N436-S439 WeakPolarHBondContact O-CB 3.39Å; N436-S439 PolarHBondContact O-N 3.33Å; N436-S439 VanDerWaalsContact OD1-CB 3.26Å; N436-S439 WeakPolarHBondContact OD1-CB 3.45Å; N436-S439 PolarHBondContact OD1-OG 3.21Å; N436-V440 PolarHBondContact O-N 3.28Å; N436-V440 VanDerWaalsContact O-N 3.1Å; N436-Q497 PolarHBondContact ND2-OE1 3.25Å; N436-Q497 PolarHBondContact OD1-O 3.21Å; N436-Q497 PolarHBondContact OD1-OE1 2.98Å; N436-E500 PolarHBondContact ND2-OE2 3.38Å
437V97.3Very high95.3Very high0 Ų028.4 Ų28.40%014%0.135CC..Hα-helixtrans-59.1-28.3-163.867.90000114.2V393 F422 L431 I432 Q435 V440 I441 I482V393-V437 HydrophobicContact CB-CG2 4.45Å; V393-V437 HydrophobicContact CG1-CB 4.07Å; V393-V437 HydrophobicContact CG1-CG2 3.88Å; V393-V437 HydrophobicContact CG2-CB 4.31Å; V393-V437 HydrophobicContact CG2-CG2 3.61Å; F422-V437 HydrophobicContact CE1-CG2 4.04Å; F422-V437 HydrophobicContact CZ-CG2 3.91Å; L431-V437 HydrophobicContact CB-CB 4.13Å; L431-V437 HydrophobicContact CB-CG1 3.77Å; L431-V437 PolarHBondContact O-N 2.84Å; I432-V437 HydrophobicContact CG1-CG1 3.79Å; Q435-V437 PolarHBondContact O-N 3.38Å; Q435-V437 VanDerWaalsContact O-N 3.13Å; V437-V440 PolarHBondContact O-N 2.86Å; V437-I441 HydrophobicContact CG2-CD1 3.93Å; V437-I441 HydrophobicContact CG2-CG1 4.23Å; V437-I441 VanDerWaalsContact O-CG1 3.24Å; V437-I441 WeakPolarHBondContact O-CG1 3.48Å; V437-I441 PolarHBondContact O-N 3.18Å; V437-I482 HydrophobicContact CG1-CD1 3.63Å; V437-I482 HydrophobicContact CG1-CG1 3.67Å
438I97.5Very high95.3Very high0 Ų029 Ų290%014%0.138CC..Hα-helixtrans-64.3-41.5174.1-61.2169.9000110.7I432 N436 T442 L479 I482 L483 F498 F549I432-I438 HydrophobicContact CD1-CD1 3.91Å; I432-I438 HydrophobicContact CD1-CG1 4.44Å; I432-I438 HydrophobicContact CG1-CD1 3.94Å; I432-I438 HydrophobicContact CG1-CG1 4.06Å; I432-I438 HydrophobicContact CG2-CD1 4.02Å; N436-I438 PolarHBondContact O-N 2.66Å; I438-T442 HydrophobicContact CG2-CG2 4.45Å; I438-T442 WeakPolarHBondContact O-CB 3.46Å; I438-T442 VanDerWaalsContact O-CG2 3.29Å; I438-T442 WeakPolarHBondContact O-CG2 3.39Å; I438-T442 PolarHBondContact O-N 3.19Å; I438-T442 PolarHBondContact O-OG1 3.11Å; I438-L479 HydrophobicContact CG2-CD1 3.98Å; I438-I482 HydrophobicContact CG1-CG2 4.02Å; I438-L483 HydrophobicContact CD1-CD2 4.02Å; I438-F498 HydrophobicContact CD1-CD2 3.86Å; I438-F549 HydrophobicContact CG2-CE1 4.23Å; I438-F549 HydrophobicContact CG2-CZ 3.95Å
439S97.4Very high95Very high3 Ų329.3 Ų29.32%0.02114%0.14CC..Hα-helixtrans-66.1-44173.7-56.20000110.7N436 I441 T442 E443 G501N436-S439 VanDerWaalsContact CG-CB 3.46Å; N436-S439 VanDerWaalsContact CG-OG 3.23Å; N436-S439 WeakPolarHBondContact ND2-CB 3.45Å; N436-S439 PolarHBondContact ND2-OG 3.33Å; N436-S439 WeakPolarHBondContact O-CA 3.2Å; N436-S439 WeakPolarHBondContact O-CB 3.39Å; N436-S439 PolarHBondContact O-N 3.33Å; N436-S439 VanDerWaalsContact OD1-CB 3.26Å; N436-S439 WeakPolarHBondContact OD1-CB 3.45Å; N436-S439 PolarHBondContact OD1-OG 3.21Å; S439-I441 PolarHBondContact O-N 2.83Å; S439-T442 WeakPolarHBondContact CA-OG1 3.5Å; S439-T442 PolarHBondContact O-N 2.8Å; S439-T442 PolarHBondContact O-OG1 2.7Å; S439-E443 VanDerWaalsContact O-CB 3.27Å; S439-E443 WeakPolarHBondContact O-CB 3.26Å; S439-E443 VanDerWaalsContact O-CG 3.29Å; S439-E443 WeakPolarHBondContact O-CG 3.37Å; S439-E443 PolarHBondContact O-N 3.07Å; S439-G501 VanDerWaalsContact OG-CA 3.24Å; S439-G501 WeakPolarHBondContact OG-CA 3.39Å; S439-G501 PolarHBondContact OG-N 2.94Å; S439-G501 VanDerWaalsContact OG-N 3.07Å
440V97.9Very high94.9Very high36 Ų3628.5 Ų28.522%0.21815%0.145CC..Hα-helixtrans-56.8-46.6176.7179.30000111.7V393 Y396 N436 V437 T444V393-V440 HydrophobicContact CG1-CG1 4.44Å; V393-V440 HydrophobicContact CG1-CG2 4.26Å; Y396-V440 HydrophobicContact CD1-CG1 4.01Å; Y396-V440 HydrophobicContact CG-CG1 4.39Å; N436-V440 PolarHBondContact O-N 3.28Å; N436-V440 VanDerWaalsContact O-N 3.1Å; V437-V440 PolarHBondContact O-N 2.86Å; V440-T444 WeakPolarHBondContact O-CB 3.12Å; V440-T444 PolarHBondContact O-N 3.16Å; V440-T444 PolarHBondContact O-OG1 3.18Å
441I98.1Very high94.6Very high0 Ų032.5 Ų32.50%016%0.164CC..Hα-helixtrans-67.1-46.3178.5-62.2163.2000111.1Y396 F422 V437 S439 E443 T444 L445 V475 L479 I482Y396-I441 HydrophobicContact CD1-CG1 4.43Å; Y396-I441 HydrophobicContact CE1-CB 4.22Å; Y396-I441 HydrophobicContact CE1-CG1 3.76Å; Y396-I441 HydrophobicContact CE1-CG2 4.39Å; Y396-I441 HydrophobicContact CE2-CG1 4.42Å; F422-I441 HydrophobicContact CD2-CD1 4.22Å; F422-I441 HydrophobicContact CE2-CD1 3.82Å; F422-I441 HydrophobicContact CE2-CG1 4.46Å; F422-I441 HydrophobicContact CZ-CD1 4.46Å; V437-I441 HydrophobicContact CG2-CD1 3.93Å; V437-I441 HydrophobicContact CG2-CG1 4.23Å; V437-I441 VanDerWaalsContact O-CG1 3.24Å; V437-I441 WeakPolarHBondContact O-CG1 3.48Å; V437-I441 PolarHBondContact O-N 3.18Å; S439-I441 PolarHBondContact O-N 2.83Å; I441-E443 PolarHBondContact O-N 2.79Å; I441-T444 WeakPolarHBondContact O-CB 3.44Å; I441-T444 PolarHBondContact O-N 2.75Å; I441-L445 PolarHBondContact O-N 3.42Å; I441-V475 HydrophobicContact CG2-CG1 3.99Å; I441-V475 WeakPolarHBondContact CG2-O 3.13Å; I441-L479 HydrophobicContact CG2-CB 3.83Å; I441-I482 HydrophobicContact CD1-CG2 4.14Å
442T97.1Very high94.3Very high0 Ų033.1 Ų33.10%017%0.166CC..Hα-helixtrans-70.2-30.9-178.2540000113.2I438 S439 L445 L446 L479 S504 F505 I508I438-T442 HydrophobicContact CG2-CG2 4.45Å; I438-T442 WeakPolarHBondContact O-CB 3.46Å; I438-T442 VanDerWaalsContact O-CG2 3.29Å; I438-T442 WeakPolarHBondContact O-CG2 3.39Å; I438-T442 PolarHBondContact O-N 3.19Å; I438-T442 PolarHBondContact O-OG1 3.11Å; S439-T442 WeakPolarHBondContact CA-OG1 3.5Å; S439-T442 PolarHBondContact O-N 2.8Å; S439-T442 PolarHBondContact O-OG1 2.7Å; T442-L445 WeakPolarHBondContact O-CB 3.27Å; T442-L445 PolarHBondContact O-N 2.86Å; T442-L446 VanDerWaalsContact O-CG 3.27Å; T442-L446 WeakPolarHBondContact O-CG 3.39Å; T442-L446 PolarHBondContact O-N 3.26Å; T442-L479 HydrophobicContact CG2-CD1 4.14Å; T442-L479 HydrophobicContact CG2-CD2 3.81Å; T442-S504 VanDerWaalsContact OG1-CB 3.22Å; T442-S504 WeakPolarHBondContact OG1-CB 3.48Å; T442-F505 HydrophobicContact CG2-CB 3.98Å; T442-F505 HydrophobicContact CG2-CD2 4.35Å; T442-I508 HydrophobicContact CG2-CD1 4.37Å
443E96.3Very high94.2Very high75 Ų7535.6 Ų35.635%0.3518%0.179SC..Hα-helixtrans-75.3-33.4172.7-70.4-177.3173.200112.3S439 I441 L445 L446 E447S439-E443 VanDerWaalsContact O-CB 3.27Å; S439-E443 WeakPolarHBondContact O-CB 3.26Å; S439-E443 VanDerWaalsContact O-CG 3.29Å; S439-E443 WeakPolarHBondContact O-CG 3.37Å; S439-E443 PolarHBondContact O-N 3.07Å; I441-E443 PolarHBondContact O-N 2.79Å; E443-L445 VanDerWaalsContact C-N 3.33Å; E443-L446 PolarHBondContact O-N 2.82Å; E443-E447 PolarHBondContact O-N 3.09Å; E443-E447 VanDerWaalsContact O-N 3.12Å
444T97Very high93.9Very high0 Ų036 Ų360%018%0.183CC..Hα-helixtrans-59.7-45.6168.9-57.80000110.5Y396 Q400 V440 I441 L446 E447 V448 V475Y396-T444 HydrophobicContact CD1-CG2 4.47Å; Y396-T444 HydrophobicContact CE1-CG2 4.2Å; Q400-T444 HydrophobicContact CB-CG2 3.85Å; Q400-T444 HydrophobicContact CG-CG2 4.35Å; V440-T444 WeakPolarHBondContact O-CB 3.12Å; V440-T444 PolarHBondContact O-N 3.16Å; V440-T444 PolarHBondContact O-OG1 3.18Å; I441-T444 WeakPolarHBondContact O-CB 3.44Å; I441-T444 PolarHBondContact O-N 2.75Å; T444-L446 PolarHBondContact O-N 2.92Å; T444-E447 PolarHBondContact O-N 2.94Å; T444-V448 PolarHBondContact O-N 3.35Å; T444-V475 HydrophobicContact CG2-CG1 4.19Å
445L95.4Very high93.7Very high2 Ų244.2 Ų44.21%0.0121%0.211CC..Hα-helixtrans-58-47.4172.1-74172.4000112.1I441 T442 E443 E447 V448 L449 V472 V475 I476 L479 I508I441-L445 PolarHBondContact O-N 3.42Å; T442-L445 WeakPolarHBondContact O-CB 3.27Å; T442-L445 PolarHBondContact O-N 2.86Å; E443-L445 VanDerWaalsContact C-N 3.33Å; L445-E447 PolarHBondContact O-N 2.95Å; L445-E447 VanDerWaalsContact O-N 3.13Å; L445-V448 PolarHBondContact O-N 2.99Å; L445-L449 HydrophobicContact CB-CD1 3.96Å; L445-L449 HydrophobicContact CD2-CD1 4.4Å; L445-L449 WeakPolarHBondContact O-CB 3.49Å; L445-L449 WeakPolarHBondContact O-CD1 3.49Å; L445-L449 WeakPolarHBondContact O-CG 3.47Å; L445-L449 PolarHBondContact O-N 2.71Å; L445-V472 HydrophobicContact CD2-CG1 4.12Å; L445-V475 HydrophobicContact CD1-CG1 4.49Å; L445-V475 HydrophobicContact CD2-CB 3.71Å; L445-V475 HydrophobicContact CD2-CG1 3.67Å; L445-V475 HydrophobicContact CG-CB 4.28Å; L445-V475 HydrophobicContact CG-CG1 3.67Å; L445-I476 HydrophobicContact CD1-CG1 4.22Å; L445-I476 HydrophobicContact CD2-CG1 3.76Å; L445-L479 HydrophobicContact CD1-CD2 4.41Å; L445-I508 HydrophobicContact CB-CD1 3.73Å; L445-I508 HydrophobicContact CD1-CD1 3.82Å; L445-I508 HydrophobicContact CG-CD1 4.43Å
446L93.3Very high93.3Very high45 Ų4546.8 Ų46.824%0.23623%0.226CC..Hα-helixtrans-63.8-15.2179.6-72.7164.6000114.5T442 E443 T444 P450 K507 I508T442-L446 VanDerWaalsContact O-CG 3.27Å; T442-L446 WeakPolarHBondContact O-CG 3.39Å; T442-L446 PolarHBondContact O-N 3.26Å; E443-L446 PolarHBondContact O-N 2.82Å; T444-L446 PolarHBondContact O-N 2.92Å; L446-P450 VanDerWaalsContact O-CD 3.27Å; L446-P450 WeakPolarHBondContact O-CD 3.22Å; L446-P450 WeakPolarHBondContact O-CG 3.5Å; L446-K507 HydrophobicContact CD1-CB 4.01Å; L446-K507 HydrophobicContact CD1-CD 3.67Å; L446-K507 HydrophobicContact CD1-CG 4.48Å; L446-K507 HydrophobicContact CD2-CB 3.88Å; L446-I508 HydrophobicContact CD1-CG1 4.48Å; L446-I508 HydrophobicContact CD2-CG1 3.64Å; L446-I508 HydrophobicContact CG-CD1 4.42Å; L446-I508 HydrophobicContact CG-CG1 3.79Å
447E93.1Very high93.1Very high88 Ų8850.5 Ų50.541%0.41125%0.246SC..Hα-helixtrans-98.8-20.1175.9-75.4-170.9-166.800114.9K397 K401 E443 T444 L445 P450K397-E447 WeakPolarHBondContact CE-OE1 3.33Å; K397-E447 WeakPolarHBondContact CE-OE2 3.41Å; K397-E447 VanDerWaalsContact NZ-CD 3.28Å; K397-E447 IonicContact NZ-OE1 3.49Å; K397-E447 PolarHBondContact NZ-OE1 3.46Å; K397-E447 IonicContact NZ-OE2 3.71Å; K397-E447 PolarHBondContact NZ-OE2 2.97Å; K401-E447 WeakPolarHBondContact CE-OE2 3.25Å; K401-E447 IonicContact NZ-OE2 2.68Å; K401-E447 PolarHBondContact NZ-OE2 3.33Å; E443-E447 PolarHBondContact O-N 3.09Å; E443-E447 VanDerWaalsContact O-N 3.12Å; T444-E447 PolarHBondContact O-N 2.94Å; L445-E447 PolarHBondContact O-N 2.95Å; L445-E447 VanDerWaalsContact O-N 3.13Å; E447-P450 WeakPolarHBondContact O-CD 3.39Å
448V91.6Very high92.9Very high20 Ų2052.4 Ų52.412%0.12126%0.255CS..Hα-helixtrans-96.8-28.9175.1-57.20000112.5K401 I404 T444 L445 V472K401-V448 HydrophobicContact CG-CG1 4Å; I404-V448 HydrophobicContact CD1-CB 4.14Å; I404-V448 HydrophobicContact CD1-CG1 3.82Å; I404-V448 HydrophobicContact CD1-CG2 4.09Å; T444-V448 PolarHBondContact O-N 3.35Å; L445-V448 PolarHBondContact O-N 2.99Å; V448-V472 HydrophobicContact CG2-CG1 4.18Å; V448-V472 HydrophobicContact CG2-CG2 4.08Å
449L89.1Confident92.6Very high9 Ų952.7 Ų52.75%0.04726%0.256CS..G310 helixtrans-68.8-19176.8-70.2172.4000116.6L445 E451 Y452 F459 V472 I508L445-L449 HydrophobicContact CB-CD1 3.96Å; L445-L449 HydrophobicContact CD2-CD1 4.4Å; L445-L449 WeakPolarHBondContact O-CB 3.49Å; L445-L449 WeakPolarHBondContact O-CD1 3.49Å; L445-L449 WeakPolarHBondContact O-CG 3.47Å; L445-L449 PolarHBondContact O-N 2.71Å; L449-E451 PolarHBondContact O-N 3.44Å; L449-Y452 HydrophobicContact CD2-CD2 4.16Å; L449-Y452 PolarHBondContact O-N 3.01Å; L449-F459 HydrophobicContact CB-CE1 3.79Å; L449-F459 HydrophobicContact CB-CZ 3.92Å; L449-F459 HydrophobicContact CD1-CZ 3.91Å; L449-F459 HydrophobicContact CD2-CE1 4.26Å; L449-F459 HydrophobicContact CD2-CZ 4.27Å; L449-F459 HydrophobicContact CG-CE1 4.43Å; L449-F459 HydrophobicContact CG-CZ 4.26Å; L449-V472 HydrophobicContact CD2-CG1 3.96Å; L449-I508 HydrophobicContact CD1-CG2 4.05Å
450P89.5Confident92.3Very high65 Ų6555.8 Ų55.842%0.42227%0.272SS..G310 helixtrans-60.7-21.5176.9-27.837.5000116.2L446 E447 Y452 L453L446-P450 VanDerWaalsContact O-CD 3.27Å; L446-P450 WeakPolarHBondContact O-CD 3.22Å; L446-P450 WeakPolarHBondContact O-CG 3.5Å; E447-P450 WeakPolarHBondContact O-CD 3.39Å; P450-Y452 PolarHBondContact O-N 2.63Å; P450-L453 HydrophobicContact CB-CD1 4.34Å; P450-L453 PolarHBondContact O-N 3.02Å
451E87.6Confident91.9Very high131 Ų13154.1 Ų54.161%0.61226%0.262SS*.G310 helixtrans-60.1-24.4172.9-170173167.800111.6L449 K468L449-E451 PolarHBondContact O-N 3.44Å; E451-K468 IonicContact OE1-NZ 3.43Å; E451-K468 PolarHBondContact OE1-NZ 3.26Å; E451-K468 IonicContact OE2-NZ 2.73Å; E451-K468 PolarHBondContact OE2-NZ 2.92Å
452Y89.8Confident91.3Very high13 Ų1361.8 Ų61.85%0.05130%0.298CS..G310 helixtrans-104.712.3-178.5-45.9-72.6000113.9L449 P450 F459 N460 F461 L469L449-Y452 HydrophobicContact CD2-CD2 4.16Å; L449-Y452 PolarHBondContact O-N 3.01Å; P450-Y452 PolarHBondContact O-N 2.63Å; Y452-F459 CarbonylContact O-C 3.56Å; Y452-F459 WeakPolarHBondContact O-CA 3.23Å; Y452-N460 PolarHBondContact O-N 3.32Å; Y452-F461 AromaticContact CD1-CD1 3.78Å; Y452-F461 HydrophobicContact CD1-CD1 3.78Å; Y452-F461 AromaticContact CD1-CE1 3.93Å; Y452-F461 HydrophobicContact CD1-CE1 3.93Å; Y452-F461 HydrophobicContact CD2-CE1 4.21Å; Y452-F461 AromaticContact CG-CD1 3.96Å; Y452-F461 HydrophobicContact CG-CD1 3.96Å; Y452-F461 AromaticContact CG-CE1 3.62Å; Y452-F461 HydrophobicContact CG-CE1 3.62Å; Y452-L469 HydrophobicContact CD2-CD1 4.43Å; Y452-L469 HydrophobicContact CE1-CD1 4.42Å; Y452-L469 HydrophobicContact CE2-CD1 3.9Å
453L91.5Very high90.6Very high52 Ų5265 Ų6527%0.27233%0.331SS..BIsolated β-bridgetrans-94.3134.6-179.4-68.3179.6000112.8P450 K458 F459 C511P450-L453 HydrophobicContact CB-CD1 4.34Å; P450-L453 PolarHBondContact O-N 3.02Å; L453-K458 CarbonylContact C-O 3.54Å; L453-K458 WeakPolarHBondContact CA-O 3.33Å; L453-F459 HydrophobicContact CD2-CD1 3.49Å; L453-F459 VanDerWaalsContact CD2-CD1 3.49Å; L453-F459 HydrophobicContact CD2-CE1 3.41Å; L453-F459 VanDerWaalsContact CD2-CE1 3.41Å; L453-F459 HydrophobicContact CD2-CG 4.24Å; L453-F459 HydrophobicContact CD2-CZ 4.17Å; L453-F459 HydrophobicContact CG-CD1 4.31Å; L453-F459 HydrophobicContact CG-CE1 4.08Å; L453-C511 HydrophobicContact CD2-CB 3.85Å
454D88.9Confident90.2Very high53 Ų5364.1 Ų64.128%0.28333%0.325SS..  trans-78.8-179.9171.692.7-29.9000112.5N456 N457 K458 N460D454-N456 PolarHBondContact O-N 3.46Å; D454-N456 VanDerWaalsContact O-N 3.09Å; D454-N456 VanDerWaalsContact OD1-CA 3.27Å; D454-N456 WeakPolarHBondContact OD1-CA 3.43Å; D454-N456 WeakPolarHBondContact OD1-CB 3.09Å; D454-N456 PolarHBondContact OD1-N 2.84Å; D454-N456 PolarHBondContact OD2-ND2 3.13Å; D454-N457 PolarHBondContact O-N 2.83Å; D454-N457 PolarHBondContact OD1-N 3.35Å; D454-N457 VanDerWaalsContact OD1-N 3.12Å; D454-K458 PolarHBondContact N-O 3.44Å; D454-K458 WeakPolarHBondContact OD1-CB 3.35Å; D454-K458 PolarHBondContact OD1-N 3.12Å; D454-N460 HydrophobicContact CB-CB 4.19Å
455R87.9Confident89.7Confident247 Ų24766.7 Ų66.793%0.93234%0.343SS*.THydrogen-bonded Turntrans-63.6-14.7179-61-179-176.1175.62.2114.4
456N87.4Confident89.2Confident115 Ų11573.9 Ų73.962%0.61538%0.377SS*.THydrogen-bonded Turntrans-98.74.7177.6-54.3-65.6000112.3D454 K458D454-N456 PolarHBondContact O-N 3.46Å; D454-N456 VanDerWaalsContact O-N 3.09Å; D454-N456 VanDerWaalsContact OD1-CA 3.27Å; D454-N456 WeakPolarHBondContact OD1-CA 3.43Å; D454-N456 WeakPolarHBondContact OD1-CB 3.09Å; D454-N456 PolarHBondContact OD1-N 2.84Å; D454-N456 PolarHBondContact OD2-ND2 3.13Å; N456-K458 VanDerWaalsContact C-N 3.3Å; N456-K458 HydrophobicContact CB-CG 4.15Å
457N90.8Very high88.8Confident107 Ų10775.6 Ų75.657%0.57239%0.386SS*.SBendtrans60.336.9-170.7-48.8-85.7000112.8D454 C511D454-N457 PolarHBondContact O-N 2.83Å; D454-N457 PolarHBondContact OD1-N 3.35Å; D454-N457 VanDerWaalsContact OD1-N 3.12Å; N457-C511 WeakPolarHBondContact O-CA 3.47Å; N457-C511 PolarHBondContact O-SG 2.85Å; N457-C511 VanDerWaalsContact O-SG 3.38Å
458K92.9Very high88.6Confident40 Ų4075.1 Ų75.117%0.17438%0.383CS..  trans-109.3150.9171.9-59-61.9175.3174.90110.4L453 D454 N456 T510 C511 Q513 M515L453-K458 CarbonylContact C-O 3.54Å; L453-K458 WeakPolarHBondContact CA-O 3.33Å; D454-K458 PolarHBondContact N-O 3.44Å; D454-K458 WeakPolarHBondContact OD1-CB 3.35Å; D454-K458 PolarHBondContact OD1-N 3.12Å; N456-K458 VanDerWaalsContact C-N 3.3Å; N456-K458 HydrophobicContact CB-CG 4.15Å; K458-T510 PolarHBondContact NZ-O 2.82Å; K458-C511 WeakPolarHBondContact CA-O 3.42Å; K458-C511 WeakPolarHBondContact CD-O 3.4Å; K458-Q513 WeakPolarHBondContact CE-O 3.18Å; K458-Q513 PolarHBondContact NZ-O 3.38Å; K458-M515 HydrophobicContact CB-CB 4.49Å
459F92.7Very high88.5Confident5 Ų574.1 Ų74.12%0.02238%0.377CS..BIsolated β-bridgetrans-67.4142.7176.2-67.8-53.9000112.5L449 Y452 L453 F461 I508 C511 M512 M515 E516L449-F459 HydrophobicContact CB-CE1 3.79Å; L449-F459 HydrophobicContact CB-CZ 3.92Å; L449-F459 HydrophobicContact CD1-CZ 3.91Å; L449-F459 HydrophobicContact CD2-CE1 4.26Å; L449-F459 HydrophobicContact CD2-CZ 4.27Å; L449-F459 HydrophobicContact CG-CE1 4.43Å; L449-F459 HydrophobicContact CG-CZ 4.26Å; Y452-F459 CarbonylContact O-C 3.56Å; Y452-F459 WeakPolarHBondContact O-CA 3.23Å; L453-F459 HydrophobicContact CD2-CD1 3.49Å; L453-F459 VanDerWaalsContact CD2-CD1 3.49Å; L453-F459 HydrophobicContact CD2-CE1 3.41Å; L453-F459 VanDerWaalsContact CD2-CE1 3.41Å; L453-F459 HydrophobicContact CD2-CG 4.24Å; L453-F459 HydrophobicContact CD2-CZ 4.17Å; L453-F459 HydrophobicContact CG-CD1 4.31Å; L453-F459 HydrophobicContact CG-CE1 4.08Å; F459-F461 HydrophobicContact CB-CE2 3.59Å; F459-F461 HydrophobicContact CB-CZ 3.64Å; F459-F461 HydrophobicContact CD1-CZ 4.08Å; F459-F461 HydrophobicContact CD2-CZ 4.5Å; F459-F461 HydrophobicContact CG-CE2 4.25Å; F459-F461 AromaticContact CG-CZ 3.83Å; F459-F461 HydrophobicContact CG-CZ 3.83Å; F459-I508 HydrophobicContact CE2-CG2 4.49Å; F459-C511 HydrophobicContact CD2-CB 4.08Å; F459-C511 HydrophobicContact CE1-CB 4.33Å; F459-C511 HydrophobicContact CE2-CB 3.62Å; F459-C511 HydrophobicContact CZ-CB 3.74Å; F459-C511 PolarHBondContact N-O 2.98Å; F459-M512 HydrophobicContact CD2-CB 4.44Å; F459-M512 HydrophobicContact CD2-CG 3.63Å; F459-M512 HydrophobicContact CE2-CG 3.63Å; F459-M515 HydrophobicContact CB-CB 4.07Å; F459-M515 HydrophobicContact CB-CG 4.49Å; F459-M515 HydrophobicContact CB-SD 3.75Å; F459-M515 HydrophobicContact CD2-SD 3.91Å; F459-M515 HydrophobicContact CG-SD 4.32Å; F459-M515 WeakPolarHBondContact O-CB 3.31Å; F459-E516 PolarHBondContact O-N 3.4Å
460N91.1Very high88.5Confident69 Ų6975.2 Ų75.237%0.36939%0.39SS..  trans-149.7119.8173.1-177.5-61000107.3Y452 D454 Q462Y452-N460 PolarHBondContact O-N 3.32Å; D454-N460 HydrophobicContact CB-CB 4.19Å; N460-Q462 VanDerWaalsContact OD1-CB 3.23Å; N460-Q462 WeakPolarHBondContact OD1-CB 3.18Å; N460-Q462 PolarHBondContact OD1-N 3.3Å; N460-Q462 VanDerWaalsContact OD1-N 3.09Å
461F89.5Confident88.6Confident1 Ų172.8 Ų72.80%0.00437%0.373CS..  trans-101.718.6-174.2-61.6-75.6000113.8Y452 F459 G463 Y464 L469 E516 A534 A535 I538Y452-F461 AromaticContact CD1-CD1 3.78Å; Y452-F461 HydrophobicContact CD1-CD1 3.78Å; Y452-F461 AromaticContact CD1-CE1 3.93Å; Y452-F461 HydrophobicContact CD1-CE1 3.93Å; Y452-F461 HydrophobicContact CD2-CE1 4.21Å; Y452-F461 AromaticContact CG-CD1 3.96Å; Y452-F461 HydrophobicContact CG-CD1 3.96Å; Y452-F461 AromaticContact CG-CE1 3.62Å; Y452-F461 HydrophobicContact CG-CE1 3.62Å; F459-F461 HydrophobicContact CB-CE2 3.59Å; F459-F461 HydrophobicContact CB-CZ 3.64Å; F459-F461 HydrophobicContact CD1-CZ 4.08Å; F459-F461 HydrophobicContact CD2-CZ 4.5Å; F459-F461 HydrophobicContact CG-CE2 4.25Å; F459-F461 AromaticContact CG-CZ 3.83Å; F459-F461 HydrophobicContact CG-CZ 3.83Å; F461-G463 PolarHBondContact O-N 3.15Å; F461-G463 VanDerWaalsContact O-N 3.08Å; F461-Y464 HydrophobicContact CB-CD1 4.19Å; F461-Y464 HydrophobicContact CB-CG 4.27Å; F461-Y464 WeakPolarHBondContact O-CB 3.2Å; F461-Y464 WeakPolarHBondContact O-CD1 3.38Å; F461-Y464 PolarHBondContact O-N 3.05Å; F461-L469 HydrophobicContact CD1-CD2 4.14Å; F461-L469 HydrophobicContact CE1-CD1 4.3Å; F461-L469 HydrophobicContact CE1-CD2 4.3Å; F461-E516 WeakPolarHBondContact CD2-OE1 3.28Å; F461-E516 PolarHBondContact N-OE1 3.05Å; F461-A534 HydrophobicContact CB-CB 3.49Å; F461-A534 VanDerWaalsContact CB-CB 3.49Å; F461-A534 HydrophobicContact CD1-CB 3.96Å; F461-A534 HydrophobicContact CD2-CB 3.88Å; F461-A534 HydrophobicContact CG-CB 3.48Å; F461-A534 VanDerWaalsContact CG-CB 3.48Å; F461-A535 HydrophobicContact CD2-CB 4.07Å; F461-A535 HydrophobicContact CE2-CB 4.26Å; F461-I538 HydrophobicContact CE1-CD1 3.59Å; F461-I538 HydrophobicContact CE2-CD1 3.84Å; F461-I538 HydrophobicContact CZ-CD1 3.14Å
462Q85.1Confident88.9Confident160 Ų16066.6 Ų66.675%0.74834%0.344SS*.THydrogen-bonded Turntrans-60.4115.7-178.1-173.3171.515.900111.5N460N460-Q462 VanDerWaalsContact OD1-CB 3.23Å; N460-Q462 WeakPolarHBondContact OD1-CB 3.18Å; N460-Q462 PolarHBondContact OD1-N 3.3Å; N460-Q462 VanDerWaalsContact OD1-N 3.09Å
463G82.5Confident89.1Confident68 Ų6868.1 Ų68.170%0.70135%0.35SS*.THydrogen-bonded Turntrans72.223.5-177.900000115.4F461 D531F461-G463 PolarHBondContact O-N 3.15Å; F461-G463 VanDerWaalsContact O-N 3.08Å; G463-D531 PolarHBondContact N-OD2 2.87Å
464Y86.9Confident89.1Confident56 Ų5665.9 Ų65.922%0.2234%0.339CS..  trans-60.9152.2176.379.6-67000113.7F461 Q466 L469 A534F461-Y464 HydrophobicContact CB-CD1 4.19Å; F461-Y464 HydrophobicContact CB-CG 4.27Å; F461-Y464 WeakPolarHBondContact O-CB 3.2Å; F461-Y464 WeakPolarHBondContact O-CD1 3.38Å; F461-Y464 PolarHBondContact O-N 3.05Å; Y464-Q466 HydrophobicContact CE2-CB 4.09Å; Y464-Q466 HydrophobicContact CE2-CG 4.45Å; Y464-L469 HydrophobicContact CD2-CB 3.93Å; Y464-L469 HydrophobicContact CD2-CD2 3.5Å; Y464-L469 HydrophobicContact CD2-CG 4.35Å; Y464-L469 HydrophobicContact CE2-CB 4.29Å; Y464-L469 HydrophobicContact CE2-CD2 3.64Å; Y464-L469 HydrophobicContact CG-CD2 4.49Å; Y464-A534 HydrophobicContact CD1-CB 4.21Å; Y464-A534 HydrophobicContact CD2-CB 4.17Å; Y464-A534 HydrophobicContact CE1-CB 3.92Å; Y464-A534 HydrophobicContact CE2-CB 3.86Å; Y464-A534 HydrophobicContact CG-CB 4.33Å
465S86.7Confident89.5Confident55 Ų5563.4 Ų63.439%0.38533%0.326SS..  trans-82.5120165.2172.60000110.4D467 K468 L469S465-D467 VanDerWaalsContact C-N 3.33Å; S465-D467 PolarHBondContact O-N 2.91Å; S465-K468 PolarHBondContact OG-N 2.9Å; S465-L469 WeakPolarHBondContact O-CB 3.37Å; S465-L469 PolarHBondContact O-N 3.43Å; S465-L469 VanDerWaalsContact O-N 3.09Å
466Q85.8Confident89.8Confident152 Ų15251.9 Ų51.971%0.7128%0.283SS*.Hα-helixtrans-64.8-35.3178.3-173.8177.7-600112.5Y464 G470Y464-Q466 HydrophobicContact CE2-CB 4.09Å; Y464-Q466 HydrophobicContact CE2-CG 4.45Å; Q466-G470 PolarHBondContact O-N 3.21Å
467D84.8Confident90.2Very high82 Ų8248 Ų4844%0.43926%0.264SS..Hα-helixtrans-66.2-56.4177.6-179.376.9000111.3S465 L469 G470 R471S465-D467 VanDerWaalsContact C-N 3.33Å; S465-D467 PolarHBondContact O-N 2.91Å; D467-L469 VanDerWaalsContact C-N 3.28Å; D467-L469 PolarHBondContact O-N 3.33Å; D467-G470 CarbonylContact O-C 3.57Å; D467-G470 VanDerWaalsContact O-CA 3.3Å; D467-G470 WeakPolarHBondContact O-CA 3.34Å; D467-G470 PolarHBondContact O-N 3.14Å; D467-R471 PolarHBondContact O-N 3.07Å; D467-R471 IonicContact OD1-NE 3.8Å; D467-R471 IonicContact OD1-NH2 3.35Å; D467-R471 IonicContact OD2-CZ 3.51Å; D467-R471 IonicContact OD2-NE 2.66Å; D467-R471 PolarHBondContact OD2-NE 3.43Å; D467-R471 IonicContact OD2-NH2 2.65Å
468K88Confident90.4Very high77 Ų7743 Ų4334%0.33524%0.237SC..Hα-helixtrans-53.2-45.5176.7-75.8-170.1173.3-168.90112E451 S465 G470 R471 V472E451-K468 IonicContact OE1-NZ 3.43Å; E451-K468 PolarHBondContact OE1-NZ 3.26Å; E451-K468 IonicContact OE2-NZ 2.73Å; E451-K468 PolarHBondContact OE2-NZ 2.92Å; S465-K468 PolarHBondContact OG-N 2.9Å; K468-G470 VanDerWaalsContact C-N 3.31Å; K468-G470 PolarHBondContact O-N 3.49Å; K468-R471 WeakPolarHBondContact O-CB 3.45Å; K468-R471 PolarHBondContact O-N 3.28Å; K468-V472 WeakPolarHBondContact O-CG2 3.42Å; K468-V472 PolarHBondContact O-N 3.37Å
469L90Very high90.6Very high0 Ų041 Ų410%023%0.229CC..Hα-helixtrans-68.5-33.9179.6-170.764.4000111.5Y452 F461 Y464 S465 D467 R471 V472 Y473 A534 I538Y452-L469 HydrophobicContact CD2-CD1 4.43Å; Y452-L469 HydrophobicContact CE1-CD1 4.42Å; Y452-L469 HydrophobicContact CE2-CD1 3.9Å; F461-L469 HydrophobicContact CD1-CD2 4.14Å; F461-L469 HydrophobicContact CE1-CD1 4.3Å; F461-L469 HydrophobicContact CE1-CD2 4.3Å; Y464-L469 HydrophobicContact CD2-CB 3.93Å; Y464-L469 HydrophobicContact CD2-CD2 3.5Å; Y464-L469 HydrophobicContact CD2-CG 4.35Å; Y464-L469 HydrophobicContact CE2-CB 4.29Å; Y464-L469 HydrophobicContact CE2-CD2 3.64Å; Y464-L469 HydrophobicContact CG-CD2 4.49Å; S465-L469 WeakPolarHBondContact O-CB 3.37Å; S465-L469 PolarHBondContact O-N 3.43Å; S465-L469 VanDerWaalsContact O-N 3.09Å; D467-L469 VanDerWaalsContact C-N 3.28Å; D467-L469 PolarHBondContact O-N 3.33Å; L469-R471 VanDerWaalsContact C-N 3.34Å; L469-V472 HydrophobicContact CD1-CB 4.38Å; L469-V472 WeakPolarHBondContact O-CB 3.48Å; L469-V472 PolarHBondContact O-N 2.89Å; L469-Y473 HydrophobicContact CD1-CE1 4.15Å; L469-Y473 HydrophobicContact CD2-CE1 4.26Å; L469-Y473 WeakPolarHBondContact CD2-OH 3.42Å; L469-Y473 HydrophobicContact CG-CE1 3.73Å; L469-Y473 VanDerWaalsContact O-CD1 3.28Å; L469-Y473 WeakPolarHBondContact O-CD1 3.34Å; L469-Y473 PolarHBondContact O-N 2.97Å; L469-Y473 VanDerWaalsContact O-N 3.09Å; L469-A534 HydrophobicContact CD2-CB 3.73Å; L469-I538 HydrophobicContact CD1-CD1 4.18Å; L469-I538 HydrophobicContact CD2-CD1 4.5Å
470G89.8Confident90.7Very high32 Ų3242.7 Ų42.733%0.3324%0.236SC..Hα-helixtrans-57.1-43.616800000112.8Q466 D467 K468 Y473Q466-G470 PolarHBondContact O-N 3.21Å; D467-G470 CarbonylContact O-C 3.57Å; D467-G470 VanDerWaalsContact O-CA 3.3Å; D467-G470 WeakPolarHBondContact O-CA 3.34Å; D467-G470 PolarHBondContact O-N 3.14Å; K468-G470 VanDerWaalsContact C-N 3.31Å; K468-G470 PolarHBondContact O-N 3.49Å; G470-Y473 WeakPolarHBondContact O-CB 3.12Å; G470-Y473 PolarHBondContact O-N 3Å
471R91.7Very high90.8Very high14 Ų1441.3 Ų41.35%0.05323%0.226CC..Hα-helixtrans-64.7-38.7173.9-61.8173.3-177.7-90.6-7.2111.8Y403 I404 D406 D407 H408 D467 K468 L469 Y473 A474Y403-R471 HydrophobicContact CE1-CB 3.91Å; Y403-R471 HydrophobicContact CE1-CG 4.17Å; Y403-R471 WeakPolarHBondContact O-CD 3.43Å; Y403-R471 PolarHBondContact O-NH1 3.49Å; I404-R471 HydrophobicContact CB-CB 4.4Å; I404-R471 HydrophobicContact CG1-CB 3.95Å; D406-R471 PolarHBondContact O-NE 2.98Å; D406-R471 PolarHBondContact O-NH1 2.91Å; D406-R471 PolarHBondContact O-NH2 3Å; D407-R471 PolarHBondContact O-NH2 2.92Å; H408-R471 PolarHBondContact O-NH1 3.23Å; H408-R471 PolarHBondContact O-NH2 3.27Å; D467-R471 PolarHBondContact O-N 3.07Å; D467-R471 IonicContact OD1-NE 3.8Å; D467-R471 IonicContact OD1-NH2 3.35Å; D467-R471 IonicContact OD2-CZ 3.51Å; D467-R471 IonicContact OD2-NE 2.66Å; D467-R471 PolarHBondContact OD2-NE 3.43Å; D467-R471 IonicContact OD2-NH2 2.65Å; K468-R471 WeakPolarHBondContact O-CB 3.45Å; K468-R471 PolarHBondContact O-N 3.28Å; L469-R471 VanDerWaalsContact C-N 3.34Å; R471-Y473 VanDerWaalsContact C-N 3.26Å; R471-Y473 PolarHBondContact O-N 3.21Å; R471-A474 WeakPolarHBondContact O-CB 3.47Å; R471-A474 PolarHBondContact O-N 3.42Å
472V93.5Very high91.1Very high1 Ų141.2 Ų41.21%0.00623%0.225CC..Hα-helixtrans-61.5-32.3173175.30000112.3I404 L445 V448 L449 K468 L469 A474 V475 I476I404-V472 HydrophobicContact CD1-CG2 3.94Å; I404-V472 HydrophobicContact CG1-CG2 4.32Å; I404-V472 HydrophobicContact CG2-CG2 4.39Å; L445-V472 HydrophobicContact CD2-CG1 4.12Å; V448-V472 HydrophobicContact CG2-CG1 4.18Å; V448-V472 HydrophobicContact CG2-CG2 4.08Å; L449-V472 HydrophobicContact CD2-CG1 3.96Å; K468-V472 WeakPolarHBondContact O-CG2 3.42Å; K468-V472 PolarHBondContact O-N 3.37Å; L469-V472 HydrophobicContact CD1-CB 4.38Å; L469-V472 WeakPolarHBondContact O-CB 3.48Å; L469-V472 PolarHBondContact O-N 2.89Å; V472-A474 PolarHBondContact O-N 2.99Å; V472-V475 PolarHBondContact O-N 2.88Å; V472-V475 VanDerWaalsContact O-N 3.14Å; V472-I476 PolarHBondContact O-N 3.47Å
473Y93.1Very high91.5Very high44 Ų4433.7 Ų33.717%0.17319%0.19CC..Hα-helixtrans-62.5-22.2174.4-56.1-25.3000113.1L469 G470 R471 V475 I476 C477 A537 I538 Q541L469-Y473 HydrophobicContact CD1-CE1 4.15Å; L469-Y473 HydrophobicContact CD2-CE1 4.26Å; L469-Y473 WeakPolarHBondContact CD2-OH 3.42Å; L469-Y473 HydrophobicContact CG-CE1 3.73Å; L469-Y473 VanDerWaalsContact O-CD1 3.28Å; L469-Y473 WeakPolarHBondContact O-CD1 3.34Å; L469-Y473 PolarHBondContact O-N 2.97Å; L469-Y473 VanDerWaalsContact O-N 3.09Å; G470-Y473 WeakPolarHBondContact O-CB 3.12Å; G470-Y473 PolarHBondContact O-N 3Å; R471-Y473 VanDerWaalsContact C-N 3.26Å; R471-Y473 PolarHBondContact O-N 3.21Å; Y473-V475 VanDerWaalsContact C-N 3.34Å; Y473-V475 PolarHBondContact O-N 3.12Å; Y473-I476 HydrophobicContact CD1-CD1 4.16Å; Y473-I476 PolarHBondContact O-N 3.43Å; Y473-C477 WeakPolarHBondContact O-CB 3.49Å; Y473-C477 PolarHBondContact O-N 3.5Å; Y473-A537 VanDerWaalsContact OH-CB 3.29Å; Y473-A537 WeakPolarHBondContact OH-CB 3.27Å; Y473-I538 HydrophobicContact CE1-CG1 3.72Å; Y473-Q541 HydrophobicContact CD1-CG 4.1Å; Y473-Q541 HydrophobicContact CG-CG 4.12Å
474A92.8Very high91.8Very high6 Ų632 Ų325%0.0517%0.165CC..Hα-helixtrans-59.2-45.8172.800000111.7Y403 R410 R471 V472 C477 D478Y403-A474 HydrophobicContact CD1-CB 4.48Å; Y403-A474 HydrophobicContact CE1-CB 3.83Å; R410-A474 PolarHBondContact NH1-O 3.16Å; R471-A474 WeakPolarHBondContact O-CB 3.47Å; R471-A474 PolarHBondContact O-N 3.42Å; V472-A474 PolarHBondContact O-N 2.99Å; A474-C477 WeakPolarHBondContact O-CB 3.46Å; A474-C477 PolarHBondContact O-N 3.33Å; A474-C477 VanDerWaalsContact O-N 3.16Å; A474-D478 PolarHBondContact O-N 2.86Å
475V95.9Very high91.7Very high0 Ų029.9 Ų29.90%016%0.158CC..Hα-helixtrans-67.6-35.8179-168.50000111.2Y396 Q400 I404 I441 T444 L445 V472 Y473 D478 L479Y396-V475 HydrophobicContact CE1-CG1 4.25Å; Q400-V475 HydrophobicContact CB-CG2 4.03Å; Q400-V475 HydrophobicContact CG-CG2 4.08Å; I404-V475 HydrophobicContact CD1-CG2 4.17Å; I441-V475 HydrophobicContact CG2-CG1 3.99Å; I441-V475 WeakPolarHBondContact CG2-O 3.13Å; T444-V475 HydrophobicContact CG2-CG1 4.19Å; L445-V475 HydrophobicContact CD1-CG1 4.49Å; L445-V475 HydrophobicContact CD2-CB 3.71Å; L445-V475 HydrophobicContact CD2-CG1 3.67Å; L445-V475 HydrophobicContact CG-CB 4.28Å; L445-V475 HydrophobicContact CG-CG1 3.67Å; V472-V475 PolarHBondContact O-N 2.88Å; V472-V475 VanDerWaalsContact O-N 3.14Å; Y473-V475 VanDerWaalsContact C-N 3.34Å; Y473-V475 PolarHBondContact O-N 3.12Å; V475-D478 PolarHBondContact O-N 2.77Å; V475-L479 PolarHBondContact O-N 3.32Å
476I95.6Very high91.7Very high6 Ų632 Ų323%0.03116%0.161CC..Hα-helixtrans-65.7-41172.2-57.3-179.3000110.4L445 V472 Y473 D478 L479 K480 Q541 L542 I545L445-I476 HydrophobicContact CD1-CG1 4.22Å; L445-I476 HydrophobicContact CD2-CG1 3.76Å; V472-I476 PolarHBondContact O-N 3.47Å; Y473-I476 HydrophobicContact CD1-CD1 4.16Å; Y473-I476 PolarHBondContact O-N 3.43Å; I476-D478 VanDerWaalsContact C-N 3.31Å; I476-D478 PolarHBondContact O-N 2.87Å; I476-L479 WeakPolarHBondContact O-CB 3.44Å; I476-L479 PolarHBondContact O-N 2.94Å; I476-K480 PolarHBondContact O-N 3.03Å; I476-K480 VanDerWaalsContact O-N 3.12Å; I476-Q541 HydrophobicContact CG2-CB 3.89Å; I476-L542 HydrophobicContact CG2-CD2 3.76Å; I476-L542 HydrophobicContact CG2-CG 4.39Å; I476-I545 HydrophobicContact CG2-CD1 3.57Å; I476-I545 VanDerWaalsContact O-CD1 3.25Å; I476-I545 WeakPolarHBondContact O-CD1 3.29Å
477C94.2Very high91.8Very high34 Ų3425 Ų2523%0.2313%0.128CC..Hα-helixtrans-62.9-37.6176.7-157.50000112Y473 A474 L479 K480 Y481Y473-C477 WeakPolarHBondContact O-CB 3.49Å; Y473-C477 PolarHBondContact O-N 3.5Å; A474-C477 WeakPolarHBondContact O-CB 3.46Å; A474-C477 PolarHBondContact O-N 3.33Å; A474-C477 VanDerWaalsContact O-N 3.16Å; C477-L479 VanDerWaalsContact C-N 3.33Å; C477-L479 PolarHBondContact O-N 3.19Å; C477-K480 WeakPolarHBondContact O-CA 3.15Å; C477-K480 VanDerWaalsContact O-CB 3.23Å; C477-K480 WeakPolarHBondContact O-CB 3.17Å; C477-K480 PolarHBondContact O-N 3.49Å; C477-Y481 HydrophobicContact CB-CE2 4.49Å; C477-Y481 WeakPolarHBondContact O-CD2 3.41Å; C477-Y481 PolarHBondContact O-N 3.36Å; C477-Y481 PolarHBondContact SG-OH 3.01Å; C477-Y481 VanDerWaalsContact SG-OH 3.4Å
478D96Very high91.8Very high0 Ų027.3 Ų27.30%015%0.145CC..Hα-helixtrans-64.4-36.5176.2-70.80.2000112.4Y396 Q400 R410 S418 F422 A474 V475 I476 K480 Y481 I482Y396-D478 WeakPolarHBondContact CE2-OD2 3.38Å; Y396-D478 VanDerWaalsContact OH-CB 3.25Å; Y396-D478 WeakPolarHBondContact OH-CB 3.47Å; Y396-D478 PolarHBondContact OH-OD2 3.36Å; Y396-D478 VanDerWaalsContact OH-OD2 3.06Å; Q400-D478 PolarHBondContact NE2-OD2 3.14Å; R410-D478 IonicContact CZ-OD1 3.82Å; R410-D478 IonicContact NH1-OD1 3.3Å; R410-D478 IonicContact NH2-OD1 2.67Å; R410-D478 PolarHBondContact NH2-OD1 3.21Å; R410-D478 IonicContact NH2-OD2 3.35Å; R410-D478 PolarHBondContact NH2-OD2 3.2Å; S418-D478 WeakPolarHBondContact CB-OD1 3.48Å; S418-D478 VanDerWaalsContact CB-OD2 3.31Å; S418-D478 WeakPolarHBondContact CB-OD2 3.39Å; S418-D478 PolarHBondContact OG-OD1 3.42Å; S418-D478 PolarHBondContact OG-OD2 3.03Å; F422-D478 HydrophobicContact CD2-CB 4.08Å; F422-D478 HydrophobicContact CE2-CB 4.05Å; A474-D478 PolarHBondContact O-N 2.86Å; V475-D478 PolarHBondContact O-N 2.77Å; I476-D478 VanDerWaalsContact C-N 3.31Å; I476-D478 PolarHBondContact O-N 2.87Å; D478-K480 VanDerWaalsContact C-N 3.3Å; D478-K480 PolarHBondContact O-N 3.37Å; D478-Y481 PolarHBondContact O-N 3Å; D478-I482 PolarHBondContact O-N 2.98Å; D478-I482 VanDerWaalsContact O-N 3.16Å
479L96.6Very high91.8Very high0 Ų030.1 Ų30.10%016%0.163CC..Hα-helixtrans-65.8-31.3170.1-175.558.5000112.3I438 I441 T442 L445 V475 I476 C477 I482 L483 F505 I545 F549I438-L479 HydrophobicContact CG2-CD1 3.98Å; I441-L479 HydrophobicContact CG2-CB 3.83Å; T442-L479 HydrophobicContact CG2-CD1 4.14Å; T442-L479 HydrophobicContact CG2-CD2 3.81Å; L445-L479 HydrophobicContact CD1-CD2 4.41Å; V475-L479 PolarHBondContact O-N 3.32Å; I476-L479 WeakPolarHBondContact O-CB 3.44Å; I476-L479 PolarHBondContact O-N 2.94Å; C477-L479 VanDerWaalsContact C-N 3.33Å; C477-L479 PolarHBondContact O-N 3.19Å; L479-I482 HydrophobicContact CD1-CG2 4.26Å; L479-L483 HydrophobicContact CD1-CD1 4.27Å; L479-L483 HydrophobicContact CG-CD1 4.38Å; L479-L483 WeakPolarHBondContact O-CD1 3.31Å; L479-L483 WeakPolarHBondContact O-CG 3.49Å; L479-F505 HydrophobicContact CD2-CD2 3.88Å; L479-F505 HydrophobicContact CD2-CE2 4.07Å; L479-I545 HydrophobicContact CB-CD1 4.27Å; L479-I545 HydrophobicContact CD2-CG2 3.97Å; L479-I545 HydrophobicContact CG-CD1 4.38Å; L479-I545 HydrophobicContact CG-CG2 4.07Å; L479-F549 HydrophobicContact CD1-CE2 4.44Å; L479-F549 HydrophobicContact CD1-CZ 4.24Å; L479-F549 HydrophobicContact CD2-CE2 4.34Å
480K94.7Very high91.8Very high39 Ų3931.5 Ų31.517%0.1717%0.168CC..Hα-helixtrans-65.5-49.7169.6-168-161.5173.4-1660110.3I476 C477 D478 I482 L483 I484 I545 M548 E794I476-K480 PolarHBondContact O-N 3.03Å; I476-K480 VanDerWaalsContact O-N 3.12Å; C477-K480 WeakPolarHBondContact O-CA 3.15Å; C477-K480 VanDerWaalsContact O-CB 3.23Å; C477-K480 WeakPolarHBondContact O-CB 3.17Å; C477-K480 PolarHBondContact O-N 3.49Å; D478-K480 VanDerWaalsContact C-N 3.3Å; D478-K480 PolarHBondContact O-N 3.37Å; K480-I482 PolarHBondContact O-N 3.41Å; K480-L483 PolarHBondContact O-N 3.46Å; K480-I484 PolarHBondContact O-N 2.86Å; K480-I545 HydrophobicContact CB-CD1 4.09Å; K480-I545 HydrophobicContact CB-CG1 3.9Å; K480-I545 HydrophobicContact CG-CG1 4.31Å; K480-M548 HydrophobicContact CG-CE 4.16Å; K480-M548 HydrophobicContact CG-SD 3.79Å; K480-M548 WeakPolarHBondContact O-CE 3.48Å; K480-E794 PolarHBondContact NZ-O 3.18Å
481Y94.2Very high92Very high40 Ų4032.5 Ų32.516%0.15717%0.168CC..Hα-helixtrans-56.1-50-175.9-63.6-39.1000112.2T120 V419 F422 T423 C477 D478 L483 I484T120-Y481 HydrophobicContact CG2-CD1 4.37Å; T120-Y481 HydrophobicContact CG2-CE1 3.88Å; V419-Y481 HydrophobicContact CB-CD2 4.1Å; V419-Y481 HydrophobicContact CB-CE2 3.69Å; V419-Y481 HydrophobicContact CG2-CD1 4.15Å; V419-Y481 HydrophobicContact CG2-CD2 4.2Å; V419-Y481 HydrophobicContact CG2-CE1 3.71Å; V419-Y481 HydrophobicContact CG2-CE2 3.78Å; V419-Y481 HydrophobicContact CG2-CG 4.4Å; F422-Y481 CarbonylContact O-C 3.44Å; F422-Y481 VanDerWaalsContact O-O 3.09Å; T423-Y481 HydrophobicContact CG2-CD1 3.95Å; T423-Y481 HydrophobicContact CG2-CG 4.12Å; C477-Y481 HydrophobicContact CB-CE2 4.49Å; C477-Y481 WeakPolarHBondContact O-CD2 3.41Å; C477-Y481 PolarHBondContact O-N 3.36Å; C477-Y481 PolarHBondContact SG-OH 3.01Å; C477-Y481 VanDerWaalsContact SG-OH 3.4Å; D478-Y481 PolarHBondContact O-N 3Å; Y481-L483 PolarHBondContact O-N 2.86Å; Y481-L483 VanDerWaalsContact O-N 3.13Å; Y481-I484 HydrophobicContact CD1-CD1 4.15Å; Y481-I484 WeakPolarHBondContact O-CB 3.46Å; Y481-I484 WeakPolarHBondContact O-CG1 3.44Å; Y481-I484 PolarHBondContact O-N 2.96Å; Y481-I484 VanDerWaalsContact O-N 3.08Å
482I95.2Very high92.1Very high0 Ų037.6 Ų37.60%019%0.192CC..Hα-helixtrans-63.2-24.1-177.2-159.376.9000113.6F422 A428 I432 V437 I438 I441 D478 L479 K480F422-I482 HydrophobicContact CB-CB 4.21Å; F422-I482 HydrophobicContact CB-CD1 3.87Å; F422-I482 HydrophobicContact CD1-CD1 3.95Å; F422-I482 HydrophobicContact CG-CD1 3.94Å; F422-I482 WeakPolarHBondContact O-CA 3.27Å; A428-I482 HydrophobicContact CB-CD1 3.76Å; I432-I482 HydrophobicContact CD1-CG1 4.1Å; I432-I482 HydrophobicContact CG1-CD1 4.49Å; I432-I482 HydrophobicContact CG1-CG1 3.99Å; V437-I482 HydrophobicContact CG1-CD1 3.63Å; V437-I482 HydrophobicContact CG1-CG1 3.67Å; I438-I482 HydrophobicContact CG1-CG2 4.02Å; I441-I482 HydrophobicContact CD1-CG2 4.14Å; D478-I482 PolarHBondContact O-N 2.98Å; D478-I482 VanDerWaalsContact O-N 3.16Å; L479-I482 HydrophobicContact CD1-CG2 4.26Å; K480-I482 PolarHBondContact O-N 3.41Å
483L93.8Very high92.1Very high2 Ų242.1 Ų42.11%0.0121%0.209CC..THydrogen-bonded Turntrans-89.2-5.7179.5-66.9173.4000113.8I438 L479 K480 Y481 S485 F498 I545 M548 F549 W552I438-L483 HydrophobicContact CD1-CD2 4.02Å; L479-L483 HydrophobicContact CD1-CD1 4.27Å; L479-L483 HydrophobicContact CG-CD1 4.38Å; L479-L483 WeakPolarHBondContact O-CD1 3.31Å; L479-L483 WeakPolarHBondContact O-CG 3.49Å; K480-L483 PolarHBondContact O-N 3.46Å; Y481-L483 PolarHBondContact O-N 2.86Å; Y481-L483 VanDerWaalsContact O-N 3.13Å; L483-S485 VanDerWaalsContact C-N 3.33Å; L483-S485 PolarHBondContact O-N 3.45Å; L483-F498 HydrophobicContact CD2-CE2 4.29Å; L483-I545 HydrophobicContact CD1-CG2 4Å; L483-M548 VanDerWaalsContact C-CE 3.42Å; L483-M548 HydrophobicContact CB-CB 4.06Å; L483-M548 HydrophobicContact CB-CE 3.84Å; L483-M548 HydrophobicContact CB-SD 4.44Å; L483-M548 HydrophobicContact CD1-CB 4.33Å; L483-M548 WeakPolarHBondContact O-CE 3.36Å; L483-F549 HydrophobicContact CD1-CD1 4.41Å; L483-F549 HydrophobicContact CD1-CD2 3.84Å; L483-F549 HydrophobicContact CD1-CE1 4.26Å; L483-F549 HydrophobicContact CD1-CE2 3.66Å; L483-F549 HydrophobicContact CD1-CG 4.22Å; L483-F549 HydrophobicContact CD1-CZ 3.89Å; L483-F549 HydrophobicContact CD2-CD1 4.41Å; L483-F549 HydrophobicContact CD2-CE1 4.18Å; L483-F549 HydrophobicContact CD2-CZ 4.47Å; L483-W552 HydrophobicContact CD2-CD2 4.17Å; L483-W552 HydrophobicContact CD2-CG 4.48Å; L483-W552 HydrophobicContact CD2-CZ2 4.29Å; L483-W552 PolarHBondContact O-NE1 3.25Å
484I89.5Confident92.2Very high31 Ų3140.3 Ų40.316%0.15920%0.202CC..SBendtrans-58.5-46.6-178.5-72.5174.7000111.1D118 T423 K480 Y481 K486 M548D118-I484 HydrophobicContact CB-CD1 4.25Å; D118-I484 HydrophobicContact CB-CG2 3.5Å; T423-I484 HydrophobicContact CG2-CD1 4.25Å; K480-I484 PolarHBondContact O-N 2.86Å; Y481-I484 HydrophobicContact CD1-CD1 4.15Å; Y481-I484 WeakPolarHBondContact O-CB 3.46Å; Y481-I484 WeakPolarHBondContact O-CG1 3.44Å; Y481-I484 PolarHBondContact O-N 2.96Å; Y481-I484 VanDerWaalsContact O-N 3.08Å; I484-K486 PolarHBondContact O-N 3.11Å; I484-M548 HydrophobicContact CB-CE 4.36Å; I484-M548 HydrophobicContact CG1-CE 3.8Å
485S83.9Confident92.3Very high12 Ų1242.8 Ų42.88%0.08421%0.211CC..SBendtrans-94.673.2-168-71.80000112.5T423 P425 L483T423-S485 PolarHBondContact O-OG 3.2Å; P425-S485 WeakPolarHBondContact CG-OG 3.37Å; L483-S485 VanDerWaalsContact C-N 3.33Å; L483-S485 PolarHBondContact O-N 3.45Å
486K87.7Confident92.3Very high101 Ų10147.5 Ų47.544%0.43923%0.234SC..  trans-55.6135.4-179.766.3-170.5171.4-1500113.3I484 E551 W552I484-K486 PolarHBondContact O-N 3.11Å; K486-E551 IonicContact NZ-OE2 2.6Å; K486-E551 PolarHBondContact NZ-OE2 3.19Å; K486-W552 HydrophobicContact CB-CD2 4.47Å; K486-W552 HydrophobicContact CB-CG 4.41Å
487P86.7Confident92.4Very high5 Ų549.1 Ų49.13%0.03224%0.241CC..  trans-73.7134.9-17429.5-35.9000111.8W490 L494 W552P487-W490 HydrophobicContact CG-CD2 4Å; P487-W490 VanDerWaalsContact CG-CE2 3.45Å; P487-W490 HydrophobicContact CG-CE3 4.41Å; P487-W490 HydrophobicContact CG-CH2 3.89Å; P487-W490 HydrophobicContact CG-CZ2 3.4Å; P487-W490 HydrophobicContact CG-CZ3 4.36Å; P487-L494 HydrophobicContact CB-CD2 3.88Å; P487-L494 HydrophobicContact CG-CD2 4.19Å; P487-W552 VanDerWaalsContact CD-CE3 3.49Å; P487-W552 VanDerWaalsContact CD-CZ3 3.44Å; P487-W552 HydrophobicContact CG-CE3 4Å; P487-W552 HydrophobicContact CG-CH2 4.4Å; P487-W552 HydrophobicContact CG-CZ3 3.87Å
488T85.1Confident92.5Very high130 Ų13047.5 Ų47.580%0.79823%0.23SC*.SBendtrans-87.1-16.6171.351.90000113.1
489I87.2Confident92.5Very high136 Ų13648.3 Ų48.370%0.69723%0.234SC*.SBendtrans-135.1131-179.7-57.5175.7000107.5
490W91.7Very high92.6Very high28 Ų2852.4 Ų52.411%0.10625%0.253CS..  trans-113.2115.2-178.4-77.198.2000111.7P487 L494 R495 F498 W552 C555 D556 L559P487-W490 HydrophobicContact CG-CD2 4Å; P487-W490 VanDerWaalsContact CG-CE2 3.45Å; P487-W490 HydrophobicContact CG-CE3 4.41Å; P487-W490 HydrophobicContact CG-CH2 3.89Å; P487-W490 HydrophobicContact CG-CZ2 3.4Å; P487-W490 HydrophobicContact CG-CZ3 4.36Å; W490-L494 HydrophobicContact CD2-CD2 4.43Å; W490-L494 HydrophobicContact CE3-CB 4.26Å; W490-L494 HydrophobicContact CE3-CD2 3.88Å; W490-L494 HydrophobicContact CE3-CG 3.79Å; W490-L494 HydrophobicContact CZ3-CD2 4.22Å; W490-L494 HydrophobicContact CZ3-CG 3.84Å; W490-R495 HydrophobicContact CB-CG 4.31Å; W490-R495 VanDerWaalsContact CB-CZ 3.46Å; W490-R495 VanDerWaalsContact CB-NH2 3.29Å; W490-R495 HydrophobicContact CD2-CG 4.28Å; W490-R495 HydrophobicContact CE3-CB 4.42Å; W490-R495 HydrophobicContact CE3-CG 3.66Å; W490-R495 HydrophobicContact CZ3-CG 4.32Å; W490-R495 PolarHBondContact O-NH1 2.74Å; W490-R495 PolarHBondContact O-NH2 2.94Å; W490-F498 HydrophobicContact CH2-CB 4.21Å; W490-F498 AromaticContact CH2-CD1 3.97Å; W490-F498 HydrophobicContact CH2-CD1 3.97Å; W490-F498 HydrophobicContact CH2-CD2 4.36Å; W490-F498 HydrophobicContact CH2-CE1 4.46Å; W490-F498 AromaticContact CH2-CG 3.91Å; W490-F498 HydrophobicContact CH2-CG 3.91Å; W490-F498 HydrophobicContact CZ3-CB 4.01Å; W490-F498 HydrophobicContact CZ3-CD1 4.39Å; W490-F498 HydrophobicContact CZ3-CG 4.22Å; W490-W552 AromaticContact CH2-CE3 3.86Å; W490-W552 HydrophobicContact CH2-CE3 3.86Å; W490-W552 HydrophobicContact CH2-CZ3 4.36Å; W490-W552 HydrophobicContact CZ2-CE3 4.22Å; W490-C555 HydrophobicContact CZ2-CB 4.47Å; W490-D556 HydrophobicContact CG-CB 4.32Å; W490-L559 HydrophobicContact CD2-CD2 4.5Å; W490-L559 HydrophobicContact CE3-CD2 4.43Å; W490-L559 HydrophobicContact CH2-CD2 3.31Å; W490-L559 HydrophobicContact CZ2-CD2 3.38Å; W490-L559 HydrophobicContact CZ3-CD2 3.87Å
491T92.7Very high92.7Very high54 Ų5450.5 Ų50.533%0.33125%0.245SC..  trans-81.6161.2165.268.20000110.1E433 R493 L494 R495E433-T491 WeakPolarHBondContact OE1-CB 3.27Å; E433-T491 PolarHBondContact OE1-OG1 3.13Å; T491-R493 VanDerWaalsContact C-N 3.31Å; T491-R493 PolarHBondContact O-N 3.27Å; T491-L494 PolarHBondContact O-N 3.01Å; T491-L494 WeakPolarHBondContact OG1-CB 3.28Å; T491-L494 PolarHBondContact OG1-N 2.83Å; T491-R495 WeakPolarHBondContact O-CG 3.48Å; T491-R495 PolarHBondContact O-N 2.93Å; T491-R495 PolarHBondContact O-NH1 3.07Å
492E93.4Very high92.9Very high121 Ų12148.7 Ų48.757%0.56524%0.238SC*.Hα-helixtrans-64.6-38175.7-170.757.4-161.500112R495 M496E492-R495 PolarHBondContact O-N 3.28Å; E492-R495 IonicContact OE2-NH1 2.75Å; E492-M496 HydrophobicContact CG-CE 4.34Å; E492-M496 WeakPolarHBondContact O-CG 3.42Å; E492-M496 PolarHBondContact O-N 3.24Å
493R95.1Very high93Very high96 Ų9653.5 Ų53.536%0.36226%0.256SS..Hα-helixtrans-62.3-47.7175.4-170.8175.9177.7178.60.5111.1E433 E434 T491 R495 M496 Q497E433-R493 HydrophobicContact CG-CB 4.04Å; E433-R493 HydrophobicContact CG-CG 3.82Å; E433-R493 PolarHBondContact O-NE 2.87Å; E433-R493 PolarHBondContact O-NH2 2.96Å; E434-R493 VanDerWaalsContact CD-CZ 3.4Å; E434-R493 IonicContact OE1-CZ 3.93Å; E434-R493 IonicContact OE1-NE 3.66Å; E434-R493 IonicContact OE1-NH1 3.69Å; E434-R493 PolarHBondContact OE1-NH1 3.08Å; E434-R493 IonicContact OE1-NH2 2.77Å; E434-R493 IonicContact OE2-CZ 2.73Å; E434-R493 IonicContact OE2-NH1 2.65Å; E434-R493 PolarHBondContact OE2-NH1 3.45Å; E434-R493 IonicContact OE2-NH2 3.43Å; E434-R493 PolarHBondContact OE2-NH2 3.12Å; T491-R493 VanDerWaalsContact C-N 3.31Å; T491-R493 PolarHBondContact O-N 3.27Å; R493-R495 VanDerWaalsContact C-N 3.34Å; R493-R495 PolarHBondContact O-N 2.97Å; R493-M496 PolarHBondContact O-N 3.21Å; R493-Q497 HydrophobicContact CG-CG 4.29Å; R493-Q497 VanDerWaalsContact O-CG 3.3Å; R493-Q497 WeakPolarHBondContact O-CG 3.41Å; R493-Q497 PolarHBondContact O-N 3.45Å
494L94.3Very high93.2Very high5 Ų553.5 Ų53.53%0.02626%0.257CS..Hα-helixtrans-59.9-41.4177-175.264.8000112.2I432 E433 P487 W490 T491 F498I432-L494 HydrophobicContact CB-CD1 3.91Å; I432-L494 HydrophobicContact CG2-CD1 3.62Å; E433-L494 HydrophobicContact CB-CD1 4.37Å; P487-L494 HydrophobicContact CB-CD2 3.88Å; P487-L494 HydrophobicContact CG-CD2 4.19Å; W490-L494 HydrophobicContact CD2-CD2 4.43Å; W490-L494 HydrophobicContact CE3-CB 4.26Å; W490-L494 HydrophobicContact CE3-CD2 3.88Å; W490-L494 HydrophobicContact CE3-CG 3.79Å; W490-L494 HydrophobicContact CZ3-CD2 4.22Å; W490-L494 HydrophobicContact CZ3-CG 3.84Å; T491-L494 PolarHBondContact O-N 3.01Å; T491-L494 WeakPolarHBondContact OG1-CB 3.28Å; T491-L494 PolarHBondContact OG1-N 2.83Å; L494-F498 VanDerWaalsContact O-CB 3.26Å; L494-F498 WeakPolarHBondContact O-CB 3.45Å; L494-F498 PolarHBondContact O-N 3.24Å
495R95.1Very high93.6Very high59 Ų5952.1 Ų52.122%0.22325%0.249CC..Hα-helixtrans-58.9-48.1173.6-72.9-175.5-171.9813.8111.8W490 T491 E492 R493 L499 D556W490-R495 HydrophobicContact CB-CG 4.31Å; W490-R495 VanDerWaalsContact CB-CZ 3.46Å; W490-R495 VanDerWaalsContact CB-NH2 3.29Å; W490-R495 HydrophobicContact CD2-CG 4.28Å; W490-R495 HydrophobicContact CE3-CB 4.42Å; W490-R495 HydrophobicContact CE3-CG 3.66Å; W490-R495 HydrophobicContact CZ3-CG 4.32Å; W490-R495 PolarHBondContact O-NH1 2.74Å; W490-R495 PolarHBondContact O-NH2 2.94Å; T491-R495 WeakPolarHBondContact O-CG 3.48Å; T491-R495 PolarHBondContact O-N 2.93Å; T491-R495 PolarHBondContact O-NH1 3.07Å; E492-R495 PolarHBondContact O-N 3.28Å; E492-R495 IonicContact OE2-NH1 2.75Å; R493-R495 VanDerWaalsContact C-N 3.34Å; R493-R495 PolarHBondContact O-N 2.97Å; R495-L499 WeakPolarHBondContact O-CB 3.03Å; R495-L499 WeakPolarHBondContact O-CG 3.32Å; R495-L499 PolarHBondContact O-N 3.22Å; R495-D556 IonicContact CZ-OD2 3.49Å; R495-D556 IonicContact NE-OD1 2.83Å; R495-D556 IonicContact NE-OD2 3.51Å; R495-D556 PolarHBondContact NE-OD2 3.48Å; R495-D556 IonicContact NH2-OD2 3.27Å; R495-D556 PolarHBondContact NH2-OD2 3.37Å
496M95.9Very high94.3Very high99 Ų9951.9 Ų51.949%0.48825%0.247SC..Hα-helixtrans-62.3-49.4-179.6-71.8-172-66.100112.4E492 R493 L499 E500E492-M496 HydrophobicContact CG-CE 4.34Å; E492-M496 WeakPolarHBondContact O-CG 3.42Å; E492-M496 PolarHBondContact O-N 3.24Å; R493-M496 PolarHBondContact O-N 3.21Å; M496-L499 PolarHBondContact O-N 3.49Å; M496-E500 PolarHBondContact O-N 2.89Å
497Q96.6Very high94.7Very high39 Ų3951.7 Ų51.718%0.18225%0.246CC..Hα-helixtrans-65-43.6-178.7-60-59.8-28.300111.5I432 N436 R493 L499 E500 G501I432-Q497 HydrophobicContact CG2-CB 4.27Å; I432-Q497 VanDerWaalsContact O-CB 3.28Å; I432-Q497 WeakPolarHBondContact O-CB 3.22Å; I432-Q497 WeakPolarHBondContact O-CG 3.46Å; N436-Q497 PolarHBondContact ND2-OE1 3.25Å; N436-Q497 PolarHBondContact OD1-O 3.21Å; N436-Q497 PolarHBondContact OD1-OE1 2.98Å; R493-Q497 HydrophobicContact CG-CG 4.29Å; R493-Q497 VanDerWaalsContact O-CG 3.3Å; R493-Q497 WeakPolarHBondContact O-CG 3.41Å; R493-Q497 PolarHBondContact O-N 3.45Å; Q497-L499 PolarHBondContact O-N 3.08Å; Q497-E500 PolarHBondContact O-N 3.14Å; Q497-G501 PolarHBondContact O-N 2.99Å
498F96.8Very high95.1Very high0 Ų051.8 Ų51.80%025%0.246CC..Hα-helixtrans-61.9-41.3174.5172.8-92000112.3I438 L483 W490 L494 E500 G501 F502 F549 W552 L559I438-F498 HydrophobicContact CD1-CD2 3.86Å; L483-F498 HydrophobicContact CD2-CE2 4.29Å; W490-F498 HydrophobicContact CH2-CB 4.21Å; W490-F498 AromaticContact CH2-CD1 3.97Å; W490-F498 HydrophobicContact CH2-CD1 3.97Å; W490-F498 HydrophobicContact CH2-CD2 4.36Å; W490-F498 HydrophobicContact CH2-CE1 4.46Å; W490-F498 AromaticContact CH2-CG 3.91Å; W490-F498 HydrophobicContact CH2-CG 3.91Å; W490-F498 HydrophobicContact CZ3-CB 4.01Å; W490-F498 HydrophobicContact CZ3-CD1 4.39Å; W490-F498 HydrophobicContact CZ3-CG 4.22Å; L494-F498 VanDerWaalsContact O-CB 3.26Å; L494-F498 WeakPolarHBondContact O-CB 3.45Å; L494-F498 PolarHBondContact O-N 3.24Å; F498-E500 VanDerWaalsContact C-N 3.34Å; F498-E500 PolarHBondContact O-N 3.43Å; F498-G501 PolarHBondContact O-N 3.08Å; F498-F502 WeakPolarHBondContact O-CB 3.49Å; F498-F502 PolarHBondContact O-N 2.96Å; F498-F549 AromaticContact CE2-CD1 3.75Å; F498-F549 HydrophobicContact CE2-CD1 3.75Å; F498-F549 AromaticContact CE2-CE1 3.91Å; F498-F549 HydrophobicContact CE2-CE1 3.91Å; F498-F549 AromaticContact CZ-CD1 3.76Å; F498-F549 HydrophobicContact CZ-CD1 3.76Å; F498-F549 HydrophobicContact CZ-CE1 4.27Å; F498-W552 HydrophobicContact CD2-CD2 4.28Å; F498-W552 AromaticContact CD2-CE3 3.45Å; F498-W552 HydrophobicContact CD2-CE3 3.45Å; F498-W552 VanDerWaalsContact CD2-CE3 3.45Å; F498-W552 AromaticContact CD2-CZ3 3.95Å; F498-W552 HydrophobicContact CD2-CZ3 3.95Å; F498-W552 HydrophobicContact CE1-CB 4.5Å; F498-W552 HydrophobicContact CE2-CB 3.63Å; F498-W552 AromaticContact CE2-CD2 3.86Å; F498-W552 HydrophobicContact CE2-CD2 3.86Å; F498-W552 AromaticContact CE2-CE3 3.48Å; F498-W552 HydrophobicContact CE2-CE3 3.48Å; F498-W552 VanDerWaalsContact CE2-CE3 3.48Å; F498-W552 AromaticContact CE2-CG 3.97Å; F498-W552 HydrophobicContact CE2-CG 3.97Å; F498-W552 HydrophobicContact CE2-CZ3 4.36Å; F498-W552 HydrophobicContact CG-CE3 4.31Å; F498-W552 HydrophobicContact CZ-CB 3.53Å; F498-W552 HydrophobicContact CZ-CE3 4.36Å; F498-W552 HydrophobicContact CZ-CG 4.37Å; F498-L559 HydrophobicContact CD1-CD1 3.73Å; F498-L559 HydrophobicContact CD1-CD2 3.95Å; F498-L559 HydrophobicContact CD1-CG 4.36Å; F498-L559 HydrophobicContact CE1-CD1 4Å; F498-L559 HydrophobicContact CE1-CD2 3.9Å; F498-L559 HydrophobicContact CE1-CG 4.27Å
499L97.1Very high95.7Very high18 Ų1845.6 Ų45.69%0.09421%0.208CC..Hα-helixtrans-65.5-34.4176.3-82.5172.3000113R495 M496 Q497 R503 L559 V562 A563R495-L499 WeakPolarHBondContact O-CB 3.03Å; R495-L499 WeakPolarHBondContact O-CG 3.32Å; R495-L499 PolarHBondContact O-N 3.22Å; M496-L499 PolarHBondContact O-N 3.49Å; Q497-L499 PolarHBondContact O-N 3.08Å; L499-R503 WeakPolarHBondContact O-CB 3.43Å; L499-R503 WeakPolarHBondContact O-CG 3.1Å; L499-R503 PolarHBondContact O-N 3.25Å; L499-L559 HydrophobicContact CD1-CD1 3.92Å; L499-L559 HydrophobicContact CD2-CD1 3.55Å; L499-L559 HydrophobicContact CG-CD1 3.43Å; L499-L559 VanDerWaalsContact CG-CD1 3.43Å; L499-V562 HydrophobicContact CD1-CB 4.36Å; L499-V562 HydrophobicContact CD1-CG1 3.8Å; L499-V562 HydrophobicContact CD2-CB 4.37Å; L499-V562 HydrophobicContact CD2-CG1 3.89Å; L499-A563 HydrophobicContact CD2-CB 4.42Å
500E97.4Very high96.1Very high85 Ų8541.3 Ų41.340%0.39719%0.189SC..Hα-helixtrans-65.8-49.4173.7-170.3167.9-149.200111.1N436 M496 Q497 F498 F502 R503 S504N436-E500 PolarHBondContact ND2-OE2 3.38Å; M496-E500 PolarHBondContact O-N 2.89Å; Q497-E500 PolarHBondContact O-N 3.14Å; F498-E500 VanDerWaalsContact C-N 3.34Å; F498-E500 PolarHBondContact O-N 3.43Å; E500-F502 VanDerWaalsContact C-N 3.32Å; E500-F502 PolarHBondContact O-N 3.35Å; E500-R503 WeakPolarHBondContact O-CB 3.41Å; E500-R503 PolarHBondContact O-N 3.15Å; E500-R503 VanDerWaalsContact O-N 3.1Å; E500-S504 PolarHBondContact O-N 3.19Å
501G97.5Very high96.2Very high0 Ų040.8 Ų40.80%019%0.189CC..Hα-helixtrans-59.4-40.8175.400000112.7S439 Q497 F498 S504 F505S439-G501 VanDerWaalsContact OG-CA 3.24Å; S439-G501 WeakPolarHBondContact OG-CA 3.39Å; S439-G501 PolarHBondContact OG-N 2.94Å; S439-G501 VanDerWaalsContact OG-N 3.07Å; Q497-G501 PolarHBondContact O-N 2.99Å; F498-G501 PolarHBondContact O-N 3.08Å; G501-S504 PolarHBondContact O-N 3.41Å; G501-F505 WeakPolarHBondContact O-CB 3.42Å; G501-F505 PolarHBondContact O-N 3.39Å
502F98.1Very high96.3Very high1 Ų138.2 Ų38.20%0.00417%0.174CC..Hα-helixtrans-64.3-41.9173.8-177.8-113.3000112.1F498 E500 S504 F505 L506 F549 A563 L618F498-F502 WeakPolarHBondContact O-CB 3.49Å; F498-F502 PolarHBondContact O-N 2.96Å; E500-F502 VanDerWaalsContact C-N 3.32Å; E500-F502 PolarHBondContact O-N 3.35Å; F502-S504 VanDerWaalsContact C-N 3.33Å; F502-S504 PolarHBondContact O-N 2.74Å; F502-F505 HydrophobicContact CD2-CD1 4.45Å; F502-F505 WeakPolarHBondContact O-CB 3.37Å; F502-F505 PolarHBondContact O-N 2.81Å; F502-L506 HydrophobicContact CD1-CD1 4.07Å; F502-L506 HydrophobicContact CD1-CG 4.4Å; F502-L506 HydrophobicContact CE1-CD1 3.67Å; F502-L506 HydrophobicContact CE1-CD2 4.26Å; F502-L506 HydrophobicContact CE1-CG 4.05Å; F502-L506 HydrophobicContact CE2-CD2 4.25Å; F502-L506 HydrophobicContact CE2-CG 4.4Å; F502-L506 HydrophobicContact CZ-CD1 4.12Å; F502-L506 HydrophobicContact CZ-CD2 3.84Å; F502-L506 HydrophobicContact CZ-CG 4.06Å; F502-L506 WeakPolarHBondContact O-CG 3.28Å; F502-L506 PolarHBondContact O-N 2.95Å; F502-F549 HydrophobicContact CB-CD1 4.41Å; F502-F549 HydrophobicContact CB-CE1 4.19Å; F502-F549 HydrophobicContact CD2-CB 4.23Å; F502-F549 AromaticContact CD2-CD1 3.57Å; F502-F549 HydrophobicContact CD2-CD1 3.57Å; F502-F549 AromaticContact CD2-CE1 3.99Å; F502-F549 HydrophobicContact CD2-CE1 3.99Å; F502-F549 AromaticContact CD2-CG 3.93Å; F502-F549 HydrophobicContact CD2-CG 3.93Å; F502-F549 HydrophobicContact CE2-CB 4.16Å; F502-F549 HydrophobicContact CE2-CD1 4.34Å; F502-F549 HydrophobicContact CE2-CG 4.3Å; F502-F549 HydrophobicContact CG-CD1 4.41Å; F502-A563 HydrophobicContact CD1-CB 4.01Å; F502-A563 HydrophobicContact CE1-CB 3.68Å; F502-A563 HydrophobicContact CZ-CB 4.42Å; F502-L618 HydrophobicContact CZ-CD1 4.17Å
503R98.1Very high96.4Very high101 Ų10132.5 Ų32.538%0.38115%0.147SC..Hα-helixtrans-62.6-38.2173.9-73.5166.7-170.6135.73.5112.2L499 E500 L506 K507 E566L499-R503 WeakPolarHBondContact O-CB 3.43Å; L499-R503 WeakPolarHBondContact O-CG 3.1Å; L499-R503 PolarHBondContact O-N 3.25Å; E500-R503 WeakPolarHBondContact O-CB 3.41Å; E500-R503 PolarHBondContact O-N 3.15Å; E500-R503 VanDerWaalsContact O-N 3.1Å; R503-L506 PolarHBondContact O-N 2.86Å; R503-K507 PolarHBondContact O-N 3.48Å; R503-E566 HydrophobicContact CG-CB 4.38Å; R503-E566 HydrophobicContact CG-CG 4.22Å
504S97.4Very high96.3Very high3 Ų328.1 Ų28.12%0.02113%0.132CC..Hα-helixtrans-68.7-39.6174-79.90000111.9T442 E500 G501 F502 L506 K507T442-S504 VanDerWaalsContact OG1-CB 3.22Å; T442-S504 WeakPolarHBondContact OG1-CB 3.48Å; E500-S504 PolarHBondContact O-N 3.19Å; G501-S504 PolarHBondContact O-N 3.41Å; F502-S504 VanDerWaalsContact C-N 3.33Å; F502-S504 PolarHBondContact O-N 2.74Å; S504-L506 PolarHBondContact O-N 2.69Å; S504-K507 VanDerWaalsContact O-CB 3.27Å; S504-K507 WeakPolarHBondContact O-CB 3.41Å; S504-K507 PolarHBondContact O-N 2.57Å; S504-K507 VanDerWaalsContact O-N 3.07Å; S504-K507 PolarHBondContact OG-NZ 3.46Å
505F97.9Very high96.2Very high1 Ų127.9 Ų27.90%0.00413%0.13CC..Hα-helixtrans-59.6-40.6170.9-176.8-117000113.1T442 L479 G501 F502 K507 I508 L509 L542 I545 L546 F549T442-F505 HydrophobicContact CG2-CB 3.98Å; T442-F505 HydrophobicContact CG2-CD2 4.35Å; L479-F505 HydrophobicContact CD2-CD2 3.88Å; L479-F505 HydrophobicContact CD2-CE2 4.07Å; G501-F505 WeakPolarHBondContact O-CB 3.42Å; G501-F505 PolarHBondContact O-N 3.39Å; F502-F505 HydrophobicContact CD2-CD1 4.45Å; F502-F505 WeakPolarHBondContact O-CB 3.37Å; F502-F505 PolarHBondContact O-N 2.81Å; F505-K507 PolarHBondContact O-N 3.29Å; F505-I508 HydrophobicContact CD2-CD1 4.35Å; F505-I508 WeakPolarHBondContact O-CB 3.44Å; F505-I508 PolarHBondContact O-N 3.04Å; F505-L509 HydrophobicContact CD1-CD1 4.2Å; F505-L509 HydrophobicContact CD1-CG 4.34Å; F505-L509 HydrophobicContact CE1-CD1 3.73Å; F505-L509 HydrophobicContact CE1-CD2 4.17Å; F505-L509 HydrophobicContact CE1-CG 4.01Å; F505-L509 HydrophobicContact CE2-CD2 4.26Å; F505-L509 HydrophobicContact CZ-CD1 4.25Å; F505-L509 HydrophobicContact CZ-CD2 3.83Å; F505-L509 HydrophobicContact CZ-CG 4.15Å; F505-L509 PolarHBondContact O-N 2.88Å; F505-L509 VanDerWaalsContact O-N 3.11Å; F505-L542 HydrophobicContact CE2-CD2 3.92Å; F505-L542 HydrophobicContact CZ-CD2 4.31Å; F505-I545 HydrophobicContact CE1-CG2 4.41Å; F505-I545 HydrophobicContact CE2-CG2 3.91Å; F505-I545 HydrophobicContact CZ-CG2 3.74Å; F505-L546 HydrophobicContact CE1-CD2 3.91Å; F505-L546 HydrophobicContact CZ-CD2 3.89Å; F505-F549 HydrophobicContact CB-CE2 4Å; F505-F549 HydrophobicContact CB-CZ 3.98Å; F505-F549 AromaticContact CD1-CD2 3.47Å; F505-F549 HydrophobicContact CD1-CD2 3.47Å; F505-F549 VanDerWaalsContact CD1-CD2 3.47Å; F505-F549 AromaticContact CD1-CE2 3.35Å; F505-F549 HydrophobicContact CD1-CE2 3.35Å; F505-F549 HydrophobicContact CD1-CG 4.28Å; F505-F549 HydrophobicContact CD1-CZ 4.08Å; F505-F549 AromaticContact CD2-CE2 3.87Å; F505-F549 HydrophobicContact CD2-CE2 3.87Å; F505-F549 AromaticContact CE1-CD2 3.45Å; F505-F549 HydrophobicContact CE1-CD2 3.45Å; F505-F549 VanDerWaalsContact CE1-CD2 3.45Å; F505-F549 AromaticContact CE1-CE2 3.66Å; F505-F549 HydrophobicContact CE1-CE2 3.66Å; F505-F549 HydrophobicContact CE1-CG 4.41Å; F505-F549 HydrophobicContact CE2-CE2 4.16Å; F505-F549 HydrophobicContact CG-CD2 4.09Å; F505-F549 AromaticContact CG-CE2 3.46Å; F505-F549 HydrophobicContact CG-CE2 3.46Å; F505-F549 VanDerWaalsContact CG-CE2 3.46Å; F505-F549 AromaticContact CG-CZ 3.97Å; F505-F549 HydrophobicContact CG-CZ 3.97Å; F505-F549 HydrophobicContact CZ-CD2 4.07Å; F505-F549 HydrophobicContact CZ-CE2 4.07Å
506L98Very high95.9Very high7 Ų726.5 Ų26.54%0.03713%0.126CC..Hα-helixtrans-61-24.3174.7-69.4175.4000113.2F502 R503 S504 L509 T510 E566 C567 L611F502-L506 HydrophobicContact CD1-CD1 4.07Å; F502-L506 HydrophobicContact CD1-CG 4.4Å; F502-L506 HydrophobicContact CE1-CD1 3.67Å; F502-L506 HydrophobicContact CE1-CD2 4.26Å; F502-L506 HydrophobicContact CE1-CG 4.05Å; F502-L506 HydrophobicContact CE2-CD2 4.25Å; F502-L506 HydrophobicContact CE2-CG 4.4Å; F502-L506 HydrophobicContact CZ-CD1 4.12Å; F502-L506 HydrophobicContact CZ-CD2 3.84Å; F502-L506 HydrophobicContact CZ-CG 4.06Å; F502-L506 WeakPolarHBondContact O-CG 3.28Å; F502-L506 PolarHBondContact O-N 2.95Å; R503-L506 PolarHBondContact O-N 2.86Å; S504-L506 PolarHBondContact O-N 2.69Å; L506-L509 HydrophobicContact CD2-CD1 4.42Å; L506-T510 WeakPolarHBondContact O-CB 3.36Å; L506-T510 PolarHBondContact O-N 3.26Å; L506-T510 PolarHBondContact O-OG1 2.76Å; L506-E566 HydrophobicContact CD1-CB 4.05Å; L506-C567 HydrophobicContact CD1-CB 4.33Å; L506-C567 HydrophobicContact CD2-CB 4.16Å; L506-L611 HydrophobicContact CD2-CD1 3.55Å
507K96.4Very high95.7Very high98 Ų9826 Ų2643%0.42612%0.123SC..Hα-helixtrans-67.3-41.9171.7-56.8165.1-170.2158.40110.7L446 R503 S504 F505 T510 C511L446-K507 HydrophobicContact CD1-CB 4.01Å; L446-K507 HydrophobicContact CD1-CD 3.67Å; L446-K507 HydrophobicContact CD1-CG 4.48Å; L446-K507 HydrophobicContact CD2-CB 3.88Å; R503-K507 PolarHBondContact O-N 3.48Å; S504-K507 VanDerWaalsContact O-CB 3.27Å; S504-K507 WeakPolarHBondContact O-CB 3.41Å; S504-K507 PolarHBondContact O-N 2.57Å; S504-K507 VanDerWaalsContact O-N 3.07Å; S504-K507 PolarHBondContact OG-NZ 3.46Å; F505-K507 PolarHBondContact O-N 3.29Å; K507-T510 VanDerWaalsContact O-CB 3.28Å; K507-T510 WeakPolarHBondContact O-CB 3.46Å; K507-T510 PolarHBondContact O-N 2.79Å; K507-T510 VanDerWaalsContact O-N 3.15Å; K507-C511 PolarHBondContact O-N 3.4Å
508I95.8Very high95.4Very high6 Ų625.5 Ų25.53%0.03112%0.121CC..Hα-helixtrans-62.2-46.8175.4-55.1172.2000109.9T442 L445 L446 L449 F459 F505 T510 C511 M512T442-I508 HydrophobicContact CG2-CD1 4.37Å; L445-I508 HydrophobicContact CB-CD1 3.73Å; L445-I508 HydrophobicContact CD1-CD1 3.82Å; L445-I508 HydrophobicContact CG-CD1 4.43Å; L446-I508 HydrophobicContact CD1-CG1 4.48Å; L446-I508 HydrophobicContact CD2-CG1 3.64Å; L446-I508 HydrophobicContact CG-CD1 4.42Å; L446-I508 HydrophobicContact CG-CG1 3.79Å; L449-I508 HydrophobicContact CD1-CG2 4.05Å; F459-I508 HydrophobicContact CE2-CG2 4.49Å; F505-I508 HydrophobicContact CD2-CD1 4.35Å; F505-I508 WeakPolarHBondContact O-CB 3.44Å; F505-I508 PolarHBondContact O-N 3.04Å; I508-T510 PolarHBondContact O-N 3.24Å; I508-C511 WeakPolarHBondContact O-CB 3.41Å; I508-C511 PolarHBondContact O-N 3.42Å; I508-C511 VanDerWaalsContact O-N 3.08Å; I508-M512 PolarHBondContact O-N 3.27Å; I508-M512 VanDerWaalsContact O-N 3.14Å
509L96.7Very high95.2Very high0 Ų032.4 Ų32.40%015%0.147CC..Hα-helixtrans-64.6-27176.3-58-167.4000113F505 L506 M512 Q513 L542 L546 P610 L611 T614F505-L509 HydrophobicContact CD1-CD1 4.2Å; F505-L509 HydrophobicContact CD1-CG 4.34Å; F505-L509 HydrophobicContact CE1-CD1 3.73Å; F505-L509 HydrophobicContact CE1-CD2 4.17Å; F505-L509 HydrophobicContact CE1-CG 4.01Å; F505-L509 HydrophobicContact CE2-CD2 4.26Å; F505-L509 HydrophobicContact CZ-CD1 4.25Å; F505-L509 HydrophobicContact CZ-CD2 3.83Å; F505-L509 HydrophobicContact CZ-CG 4.15Å; F505-L509 PolarHBondContact O-N 2.88Å; F505-L509 VanDerWaalsContact O-N 3.11Å; L506-L509 HydrophobicContact CD2-CD1 4.42Å; L509-M512 HydrophobicContact CD2-SD 4.01Å; L509-M512 PolarHBondContact O-N 2.96Å; L509-Q513 WeakPolarHBondContact O-CB 3.45Å; L509-Q513 PolarHBondContact O-N 2.8Å; L509-L542 HydrophobicContact CD2-CD1 4.47Å; L509-L546 HydrophobicContact CD1-CD2 3.68Å; L509-L546 HydrophobicContact CD2-CD2 3.96Å; L509-L546 HydrophobicContact CG-CD2 4.47Å; L509-P610 HydrophobicContact CD2-CB 4.24Å; L509-P610 HydrophobicContact CD2-CG 4.35Å; L509-L611 HydrophobicContact CB-CB 4.12Å; L509-L611 HydrophobicContact CB-CD1 3.98Å; L509-L611 HydrophobicContact CD1-CD1 4.43Å; L509-T614 WeakPolarHBondContact CD1-OG1 3.39Å
510T95.7Very high95Very high46 Ų4634.3 Ų34.328%0.28215%0.153SC..Hα-helixtrans-66.7-35.9173.1-65.10000111.7K458 L506 K507 I508K458-T510 PolarHBondContact NZ-O 2.82Å; L506-T510 WeakPolarHBondContact O-CB 3.36Å; L506-T510 PolarHBondContact O-N 3.26Å; L506-T510 PolarHBondContact O-OG1 2.76Å; K507-T510 VanDerWaalsContact O-CB 3.28Å; K507-T510 WeakPolarHBondContact O-CB 3.46Å; K507-T510 PolarHBondContact O-N 2.79Å; K507-T510 VanDerWaalsContact O-N 3.15Å; I508-T510 PolarHBondContact O-N 3.24Å
511C94.6Very high94.7Very high18 Ų1834 Ų3412%0.12215%0.152CC..Hα-helixtrans-70.8-31.9171.9-66.40000112.5L453 N457 K458 F459 K507 I508L453-C511 HydrophobicContact CD2-CB 3.85Å; N457-C511 WeakPolarHBondContact O-CA 3.47Å; N457-C511 PolarHBondContact O-SG 2.85Å; N457-C511 VanDerWaalsContact O-SG 3.38Å; K458-C511 WeakPolarHBondContact CA-O 3.42Å; K458-C511 WeakPolarHBondContact CD-O 3.4Å; F459-C511 HydrophobicContact CD2-CB 4.08Å; F459-C511 HydrophobicContact CE1-CB 4.33Å; F459-C511 HydrophobicContact CE2-CB 3.62Å; F459-C511 HydrophobicContact CZ-CB 3.74Å; F459-C511 PolarHBondContact N-O 2.98Å; K507-C511 PolarHBondContact O-N 3.4Å; I508-C511 WeakPolarHBondContact O-CB 3.41Å; I508-C511 PolarHBondContact O-N 3.42Å; I508-C511 VanDerWaalsContact O-N 3.08Å
512M94.9Very high94.1Very high0 Ų038.7 Ų38.70%018%0.18CC..Hα-helixtrans-78.6-30175.8-62.4-17877.200114.6F459 I508 L509 G514 M515 I538 L542 P610F459-M512 HydrophobicContact CD2-CB 4.44Å; F459-M512 HydrophobicContact CD2-CG 3.63Å; F459-M512 HydrophobicContact CE2-CG 3.63Å; I508-M512 PolarHBondContact O-N 3.27Å; I508-M512 VanDerWaalsContact O-N 3.14Å; L509-M512 HydrophobicContact CD2-SD 4.01Å; L509-M512 PolarHBondContact O-N 2.96Å; M512-G514 PolarHBondContact O-N 3.39Å; M512-M515 HydrophobicContact CB-SD 3.87Å; M512-M515 HydrophobicContact CE-CE 3.81Å; M512-M515 HydrophobicContact CE-SD 4.3Å; M512-M515 HydrophobicContact CG-SD 3.97Å; M512-M515 WeakPolarHBondContact O-CB 3.32Å; M512-M515 VanDerWaalsContact O-CG 3.26Å; M512-M515 WeakPolarHBondContact O-CG 3.37Å; M512-M515 PolarHBondContact O-N 3.47Å; M512-I538 HydrophobicContact CE-CG2 3.82Å; M512-I538 HydrophobicContact SD-CG2 4.32Å; M512-L542 HydrophobicContact CE-CD1 3.85Å; M512-L542 HydrophobicContact SD-CD1 3.29Å; M512-L542 WeakPolarHBondContact SD-CD1 3.3Å; M512-P610 HydrophobicContact CB-CG 3.47Å; M512-P610 VanDerWaalsContact CB-CG 3.47Å; M512-P610 HydrophobicContact CE-CG 4.15Å; M512-P610 HydrophobicContact CG-CG 4.35Å; M512-P610 HydrophobicContact SD-CG 3.99Å
513Q94.8Very high93.3Very high1 Ų141.1 Ų41.11%0.00521%0.205CC..THydrogen-bonded Turntrans-65.2103.7-174.1177.968.128.900111K458 L509 C574 L609 L611 S612K458-Q513 WeakPolarHBondContact CE-O 3.18Å; K458-Q513 PolarHBondContact NZ-O 3.38Å; L509-Q513 WeakPolarHBondContact O-CB 3.45Å; L509-Q513 PolarHBondContact O-N 2.8Å; Q513-C574 HydrophobicContact CG-CB 3.96Å; Q513-L609 VanDerWaalsContact OE1-CA 3.32Å; Q513-L609 PolarHBondContact OE1-O 3.33Å; Q513-L611 HydrophobicContact CB-CB 3.95Å; Q513-L611 HydrophobicContact CB-CD2 4.3Å; Q513-L611 HydrophobicContact CG-CB 4.17Å; Q513-L611 HydrophobicContact CG-CD2 4.42Å; Q513-S612 PolarHBondContact NE2-OG 3.42Å; Q513-S612 VanDerWaalsContact OE1-N 3.12Å
514G92.8Very high92.4Very high4 Ų444.4 Ų44.44%0.04123%0.225CC..THydrogen-bonded Turntrans74.835.6-172.400000113.1M512 E517 H608M512-G514 PolarHBondContact O-N 3.39Å; G514-E517 VanDerWaalsContact O-CG 3.3Å; G514-E517 WeakPolarHBondContact O-CG 3.18Å; G514-H608 PolarHBondContact N-O 3Å
515M92.7Very high91.6Very high0 Ų049.4 Ų49.40%025%0.248CC..  trans-75.7156.3166.972.6-173.6-171.800111.3K458 F459 M512 E517 A535 S606 H608K458-M515 HydrophobicContact CB-CB 4.49Å; F459-M515 HydrophobicContact CB-CB 4.07Å; F459-M515 HydrophobicContact CB-CG 4.49Å; F459-M515 HydrophobicContact CB-SD 3.75Å; F459-M515 HydrophobicContact CD2-SD 3.91Å; F459-M515 HydrophobicContact CG-SD 4.32Å; F459-M515 WeakPolarHBondContact O-CB 3.31Å; M512-M515 HydrophobicContact CB-SD 3.87Å; M512-M515 HydrophobicContact CE-CE 3.81Å; M512-M515 HydrophobicContact CE-SD 4.3Å; M512-M515 HydrophobicContact CG-SD 3.97Å; M512-M515 WeakPolarHBondContact O-CB 3.32Å; M512-M515 VanDerWaalsContact O-CG 3.26Å; M512-M515 WeakPolarHBondContact O-CG 3.37Å; M512-M515 PolarHBondContact O-N 3.47Å; M515-E517 PolarHBondContact O-N 2.86Å; M515-A535 HydrophobicContact CE-CB 3.76Å; M515-S606 VanDerWaalsContact O-CB 3.29Å; M515-S606 WeakPolarHBondContact O-CB 3.49Å; M515-S606 PolarHBondContact O-OG 2.94Å; M515-H608 HydrophobicContact CE-CB 3.77Å; M515-H608 VanDerWaalsContact CE-CG 3.48Å; M515-H608 VanDerWaalsContact CE-ND1 3.3Å; M515-H608 WeakPolarHBondContact CE-ND1 3.35Å; M515-H608 HydrophobicContact CG-CB 3.58Å; M515-H608 HydrophobicContact SD-CB 4.38Å
516E89.4Confident90.9Very high30 Ų3051.5 Ų51.514%0.1426%0.259CS..SBendtrans49.649.9179.6-56.3-164.9155.400114.1F459 F461 I518 A535F459-E516 PolarHBondContact O-N 3.4Å; F461-E516 WeakPolarHBondContact CD2-OE1 3.28Å; F461-E516 PolarHBondContact N-OE1 3.05Å; E516-I518 PolarHBondContact O-N 2.95Å; E516-A535 HydrophobicContact CG-CB 4.5Å; E516-A535 WeakPolarHBondContact OE2-CB 3.36Å
517E90.6Very high89.9Confident87 Ų8760.1 Ų60.141%0.40730%0.299SS..  trans-65.2128.2178.1-56.6-168.3122.600112.2G514 M515 L604 V605G514-E517 VanDerWaalsContact O-CG 3.3Å; G514-E517 WeakPolarHBondContact O-CG 3.18Å; M515-E517 PolarHBondContact O-N 2.86Å; E517-L604 HydrophobicContact CB-CB 4Å; E517-L604 HydrophobicContact CB-CD2 4Å; E517-L604 HydrophobicContact CB-CG 4.45Å; E517-V605 CarbonylContact C-O 3.57Å; E517-V605 WeakPolarHBondContact CA-O 3.18Å
518I91.2Very high89Confident30 Ų3061.3 Ų61.315%0.15431%0.314CS..BIsolated β-bridgetrans-101.6152.5178.961.6175.1000111.3E516 L604 V605 L655 W664 L671E516-I518 PolarHBondContact O-N 2.95Å; I518-L604 WeakPolarHBondContact O-CA 3.25Å; I518-V605 HydrophobicContact CG1-CG1 3.96Å; I518-V605 WeakPolarHBondContact CG1-O 3.3Å; I518-V605 PolarHBondContact N-O 3.2Å; I518-V605 PolarHBondContact O-N 3.23Å; I518-L655 HydrophobicContact CD1-CD1 4.21Å; I518-L655 HydrophobicContact CD1-CD2 4.07Å; I518-W664 HydrophobicContact CD1-CE3 4.4Å; I518-W664 HydrophobicContact CD1-CZ3 3.89Å; I518-W664 HydrophobicContact CG1-CH2 4.43Å; I518-W664 HydrophobicContact CG1-CZ3 4.02Å; I518-L671 HydrophobicContact CD1-CD1 3.32Å; I518-L671 HydrophobicContact CD1-CD2 4.01Å; I518-L671 HydrophobicContact CD1-CG 4.22Å
519R92.4Very high88.1Confident145 Ų14564.1 Ų64.155%0.54733%0.329SS..  trans-123.7139.7172.6-162.5176.9-170.5-176.74.8110.8Q521 E602 L604 N667R519-Q521 PolarHBondContact O-N 3.06Å; R519-Q521 PolarHBondContact O-NE2 3.02Å; R519-E602 PolarHBondContact NE-O 3.08Å; R519-E602 PolarHBondContact NH2-O 3.38Å; R519-L604 HydrophobicContact CB-CD2 3.99Å; R519-N667 PolarHBondContact O-ND2 2.67Å
520R93.3Very high87.2Confident58 Ų5867.4 Ų67.422%0.21935%0.35CS..  trans-63.1131.1-179.6-170.6-170.9172.4-1530.3112V522 S601 M663 W664R520-V522 HydrophobicContact CG-CG2 4.42Å; R520-S601 WeakPolarHBondContact CD-O 2.99Å; R520-M663 PolarHBondContact NE-O 2.78Å; R520-M663 PolarHBondContact NH2-O 3.43Å; R520-M663 VanDerWaalsContact NH2-O 3.13Å; R520-W664 VanDerWaalsContact CA-CZ3 3.41Å; R520-W664 HydrophobicContact CB-CD2 4.04Å; R520-W664 HydrophobicContact CB-CE3 3.91Å; R520-W664 HydrophobicContact CB-CH2 3.73Å; R520-W664 HydrophobicContact CB-CZ2 3.84Å; R520-W664 HydrophobicContact CB-CZ3 3.76Å; R520-W664 HydrophobicContact CG-CD2 3.89Å; R520-W664 HydrophobicContact CG-CE3 4.11Å; R520-W664 HydrophobicContact CG-CG 4.32Å; R520-W664 HydrophobicContact CG-CZ2 4.4Å; R520-W664 HydrophobicContact CG-CZ3 4.47Å
521Q90.6Very high86.5Confident78 Ų7868.4 Ų68.436%0.36435%0.354SS..  trans-90.7117.1175.8-60.6-55.7-28.500111.6R519 I526 R666 N667R519-Q521 PolarHBondContact O-N 3.06Å; R519-Q521 PolarHBondContact O-NE2 3.02Å; Q521-I526 HydrophobicContact CG-CG2 3.91Å; Q521-R666 HydrophobicContact CB-CB 3.83Å; Q521-R666 WeakPolarHBondContact O-CB 3.3Å; Q521-N667 PolarHBondContact N-OD1 3.41Å
522V84.3Confident86.1Confident99 Ų9969 Ų6960%0.635%0.353SS*.  trans-108.3-3-179.5-1670000111.7R520 R666R520-V522 HydrophobicContact CG-CG2 4.42Å; V522-R666 VanDerWaalsContact C-NH1 3.28Å; V522-R666 PolarHBondContact O-NH1 2.8Å
523G82.3Confident85.8Confident51 Ų5173.2 Ų73.253%0.52637%0.373SS..SBendtrans-103.3-123.3178.700000112.8R666G523-R666 VanDerWaalsContact O-CD 3.22Å; G523-R666 WeakPolarHBondContact O-CD 3.45Å; G523-R666 PolarHBondContact O-NH1 2.81Å
524Q78.3Confident85.6Confident170 Ų17073.1 Ų73.179%0.79437%0.373SS*.SBendtrans-68.2163.3172.1-72.1168.4-38.200111.5
525H81.4Confident85.6Confident109 Ų10973 Ų7351%0.50537%0.371SS..PPolyproline II helixtrans-74.5150.6168.1-174.685.6000109E527 R665H525-E527 PolarHBondContact O-N 3.06Å; H525-R665 PolarHBondContact ND1-O 2.77Å
526I82.8Confident85.5Confident45 Ų4573.3 Ų73.323%0.23137%0.373CS..PPolyproline II helixtrans-67.9131.6174.166.2176.8000110.1Q521 R666 N667Q521-I526 HydrophobicContact CG-CG2 3.91Å; I526-R666 PolarHBondContact N-O 3.3Å; I526-N667 WeakPolarHBondContact CD1-O 3.38Å
527E76.2Confident85.6Confident188 Ų18873 Ų7388%0.87938%0.376SS*.SBendtrans-82.2-20.5-176.6-62.8-174.4160.700112.9H525H525-E527 PolarHBondContact O-N 3.06Å
528V77.9Confident85.6Confident123 Ų12369.2 Ų69.275%0.74536%0.358SS*.SBendtrans-133.6126.2178.2-176.90000107.7
529D76.5Confident85.6Confident65 Ų6567.9 Ų67.935%0.34835%0.351SS..PPolyproline II helixtrans-69.3135.6171.4-93.6-51.1000109.5G668 L669 S670D529-G668 VanDerWaalsContact OD1-CA 3.29Å; D529-G668 WeakPolarHBondContact OD1-CA 3.48Å; D529-L669 PolarHBondContact OD1-N 2.79Å; D529-L669 PolarHBondContact OD2-N 2.75Å; D529-L669 VanDerWaalsContact OD2-N 3.16Å; D529-S670 VanDerWaalsContact OD1-CB 3.29Å; D529-S670 WeakPolarHBondContact OD1-CB 3.5Å; D529-S670 PolarHBondContact OD1-N 2.87Å
530P79.4Confident85.5Confident68 Ų6863.9 Ų63.944%0.44234%0.339SS..PPolyproline II helixtrans-73.8144.1175.930.3-34.5000111.3W532 S670P530-W532 PolarHBondContact O-N 2.82Å; P530-S670 PolarHBondContact O-OG 3.42Å
531D80Confident85.3Confident68 Ų6865 Ų6536%0.36435%0.347SS..PPolyproline II helixtrans-52.5122.5169.4-53.9-48.9000109.4G463G463-D531 PolarHBondContact N-OD2 2.87Å
532W85.9Confident85.4Confident30 Ų3061.5 Ų61.511%0.11433%0.331CS..  trans-133.1-15.6-175.864-80.5000112.4P530 A534 A535 I536 S670 Q674 Y677P530-W532 PolarHBondContact O-N 2.82Å; W532-A534 VanDerWaalsContact C-N 3.32Å; W532-A534 PolarHBondContact O-N 2.86Å; W532-A535 PolarHBondContact O-N 3.06Å; W532-I536 HydrophobicContact CE3-CB 4.35Å; W532-I536 HydrophobicContact CE3-CG1 3.77Å; W532-I536 HydrophobicContact CZ3-CB 4.21Å; W532-I536 HydrophobicContact CZ3-CG1 3.91Å; W532-I536 HydrophobicContact CZ3-CG2 4.45Å; W532-I536 PolarHBondContact O-N 3.1Å; W532-S670 WeakPolarHBondContact CB-OG 3.47Å; W532-Q674 HydrophobicContact CB-CG 4.09Å; W532-Q674 HydrophobicContact CD2-CG 4.34Å; W532-Q674 HydrophobicContact CE3-CG 4.11Å; W532-Q674 HydrophobicContact CG-CG 4.33Å; W532-Y677 AromaticContact CH2-CD2 3.83Å; W532-Y677 HydrophobicContact CH2-CD2 3.83Å; W532-Y677 AromaticContact CH2-CE2 3.42Å; W532-Y677 HydrophobicContact CH2-CE2 3.42Å; W532-Y677 VanDerWaalsContact CH2-CE2 3.42Å; W532-Y677 AromaticContact CZ3-CD2 3.55Å; W532-Y677 HydrophobicContact CZ3-CD2 3.55Å; W532-Y677 AromaticContact CZ3-CE2 3.63Å; W532-Y677 HydrophobicContact CZ3-CE2 3.63Å
533E89.9Confident85.7Confident88 Ų8858.5 Ų58.541%0.41131%0.31SS..Hα-helixtrans-62.7-37.9-176.3-68.980.5176.300111.6I536 A537E533-I536 PolarHBondContact O-N 2.99Å; E533-A537 WeakPolarHBondContact O-CB 3.34Å; E533-A537 PolarHBondContact O-N 3.34Å
534A90.7Very high86.1Confident0 Ų057.2 Ų57.20%029%0.291CS..Hα-helixtrans-63.8-45.5179.600000112.7F461 Y464 L469 W532 I536 A537 I538F461-A534 HydrophobicContact CB-CB 3.49Å; F461-A534 VanDerWaalsContact CB-CB 3.49Å; F461-A534 HydrophobicContact CD1-CB 3.96Å; F461-A534 HydrophobicContact CD2-CB 3.88Å; F461-A534 HydrophobicContact CG-CB 3.48Å; F461-A534 VanDerWaalsContact CG-CB 3.48Å; Y464-A534 HydrophobicContact CD1-CB 4.21Å; Y464-A534 HydrophobicContact CD2-CB 4.17Å; Y464-A534 HydrophobicContact CE1-CB 3.92Å; Y464-A534 HydrophobicContact CE2-CB 3.86Å; Y464-A534 HydrophobicContact CG-CB 4.33Å; L469-A534 HydrophobicContact CD2-CB 3.73Å; W532-A534 VanDerWaalsContact C-N 3.32Å; W532-A534 PolarHBondContact O-N 2.86Å; A534-I536 PolarHBondContact O-N 2.73Å; A534-A537 PolarHBondContact O-N 3.39Å; A534-I538 PolarHBondContact O-N 3.34Å
535A91Very high86.9Confident0 Ų049.1 Ų49.10%025%0.253CS..Hα-helixtrans-63.6-41.6178.400000112.4F461 M515 E516 W532 Q539F461-A535 HydrophobicContact CD2-CB 4.07Å; F461-A535 HydrophobicContact CE2-CB 4.26Å; M515-A535 HydrophobicContact CE-CB 3.76Å; E516-A535 HydrophobicContact CG-CB 4.5Å; E516-A535 WeakPolarHBondContact OE2-CB 3.36Å; W532-A535 PolarHBondContact O-N 3.06Å; A535-Q539 WeakPolarHBondContact O-CB 3.48Å; A535-Q539 PolarHBondContact O-N 3.07Å; A535-Q539 VanDerWaalsContact O-N 3.16Å
536I91.1Very high87.5Confident7 Ų744 Ų444%0.03623%0.229CC..Hα-helixtrans-68.6-39.1172.7-68.3-67000111.2W532 E533 A534 Q539 M540 I607 Y677W532-I536 HydrophobicContact CE3-CB 4.35Å; W532-I536 HydrophobicContact CE3-CG1 3.77Å; W532-I536 HydrophobicContact CZ3-CB 4.21Å; W532-I536 HydrophobicContact CZ3-CG1 3.91Å; W532-I536 HydrophobicContact CZ3-CG2 4.45Å; W532-I536 PolarHBondContact O-N 3.1Å; E533-I536 PolarHBondContact O-N 2.99Å; A534-I536 PolarHBondContact O-N 2.73Å; I536-Q539 WeakPolarHBondContact O-CB 3.45Å; I536-Q539 PolarHBondContact O-N 3.37Å; I536-M540 HydrophobicContact CG2-CG 4.36Å; I536-M540 HydrophobicContact CG2-SD 4.23Å; I536-M540 WeakPolarHBondContact O-CB 3.4Å; I536-M540 WeakPolarHBondContact O-CG 3.38Å; I536-M540 PolarHBondContact O-N 3.33Å; I536-I607 HydrophobicContact CD1-CD1 4.19Å; I536-Y677 HydrophobicContact CG2-CD1 4.07Å; I536-Y677 HydrophobicContact CG2-CD2 4.49Å; I536-Y677 HydrophobicContact CG2-CG 4.02Å
537A91.5Very high88Confident25 Ų2543.4 Ų43.421%0.20723%0.226CC..Hα-helixtrans-61.8-47.3178.100000112Y473 E533 A534 Q539 M540 Q541Y473-A537 VanDerWaalsContact OH-CB 3.29Å; Y473-A537 WeakPolarHBondContact OH-CB 3.27Å; E533-A537 WeakPolarHBondContact O-CB 3.34Å; E533-A537 PolarHBondContact O-N 3.34Å; A534-A537 PolarHBondContact O-N 3.39Å; A537-Q539 PolarHBondContact O-N 2.95Å; A537-M540 WeakPolarHBondContact O-CB 3.46Å; A537-M540 PolarHBondContact O-N 3.03Å; A537-M540 VanDerWaalsContact O-N 3.14Å; A537-Q541 WeakPolarHBondContact O-CG 3.39Å; A537-Q541 PolarHBondContact O-N 3.38Å
538I91Very high88.8Confident6 Ų634.5 Ų34.53%0.03119%0.185CC..Hα-helixtrans-61-44.4174.5-68.3170.1000111F461 L469 Y473 M512 A534 M540 Q541 L542F461-I538 HydrophobicContact CE1-CD1 3.59Å; F461-I538 HydrophobicContact CE2-CD1 3.84Å; F461-I538 HydrophobicContact CZ-CD1 3.14Å; L469-I538 HydrophobicContact CD1-CD1 4.18Å; L469-I538 HydrophobicContact CD2-CD1 4.5Å; Y473-I538 HydrophobicContact CE1-CG1 3.72Å; M512-I538 HydrophobicContact CE-CG2 3.82Å; M512-I538 HydrophobicContact SD-CG2 4.32Å; A534-I538 PolarHBondContact O-N 3.34Å; I538-M540 PolarHBondContact O-N 2.72Å; I538-Q541 PolarHBondContact O-N 3.23Å; I538-L542 HydrophobicContact CG2-CD1 3.79Å; I538-L542 HydrophobicContact CG2-CG 4.34Å; I538-L542 WeakPolarHBondContact O-CB 3.43Å; I538-L542 WeakPolarHBondContact O-CG 3.48Å; I538-L542 PolarHBondContact O-N 3.33Å
539Q91.1Very high89.7Confident3 Ų328.7 Ų28.71%0.01415%0.15CC..Hα-helixtrans-58.2-38.8175.7-175.568.640.200111.5A535 I536 A537 K543 M687A535-Q539 WeakPolarHBondContact O-CB 3.48Å; A535-Q539 PolarHBondContact O-N 3.07Å; A535-Q539 VanDerWaalsContact O-N 3.16Å; I536-Q539 WeakPolarHBondContact O-CB 3.45Å; I536-Q539 PolarHBondContact O-N 3.37Å; A537-Q539 PolarHBondContact O-N 2.95Å; Q539-K543 PolarHBondContact O-N 2.97Å; Q539-K543 VanDerWaalsContact O-N 3.11Å; Q539-M687 HydrophobicContact CG-CE 4.2Å; Q539-M687 HydrophobicContact CG-SD 3.99Å
540M89.6Confident90.6Very high60 Ų6025.7 Ų25.730%0.29613%0.133SC..Hα-helixtrans-69-38.8175.4-75.4-174.164.800113.3I536 A537 I538 K543 K682I536-M540 HydrophobicContact CG2-CG 4.36Å; I536-M540 HydrophobicContact CG2-SD 4.23Å; I536-M540 WeakPolarHBondContact O-CB 3.4Å; I536-M540 WeakPolarHBondContact O-CG 3.38Å; I536-M540 PolarHBondContact O-N 3.33Å; A537-M540 WeakPolarHBondContact O-CB 3.46Å; A537-M540 PolarHBondContact O-N 3.03Å; A537-M540 VanDerWaalsContact O-N 3.14Å; I538-M540 PolarHBondContact O-N 2.72Å; M540-K543 WeakPolarHBondContact O-CG 3.3Å; M540-K682 HydrophobicContact CE-CB 4.4Å; M540-K682 HydrophobicContact CE-CD 4.09Å
541Q90.6Very high91.2Very high83 Ų8323.7 Ų23.739%0.38812%0.118SC..Hα-helixtrans-65.4-40.8174.6-61.7-54-2100111.4Y473 I476 A537 I538Y473-Q541 HydrophobicContact CD1-CG 4.1Å; Y473-Q541 HydrophobicContact CG-CG 4.12Å; I476-Q541 HydrophobicContact CG2-CB 3.89Å; A537-Q541 WeakPolarHBondContact O-CG 3.39Å; A537-Q541 PolarHBondContact O-N 3.38Å; I538-Q541 PolarHBondContact O-N 3.23Å
542L92.5Very high92Very high4 Ų420.7 Ų20.72%0.02110%0.102CC..Hα-helixtrans-76.7-19.8-177.4-70.1176.1000114.4I476 F505 L509 M512 I538 N544 I545 L546I476-L542 HydrophobicContact CG2-CD2 3.76Å; I476-L542 HydrophobicContact CG2-CG 4.39Å; F505-L542 HydrophobicContact CE2-CD2 3.92Å; F505-L542 HydrophobicContact CZ-CD2 4.31Å; L509-L542 HydrophobicContact CD2-CD1 4.47Å; M512-L542 HydrophobicContact CE-CD1 3.85Å; M512-L542 HydrophobicContact SD-CD1 3.29Å; M512-L542 WeakPolarHBondContact SD-CD1 3.3Å; I538-L542 HydrophobicContact CG2-CD1 3.79Å; I538-L542 HydrophobicContact CG2-CG 4.34Å; I538-L542 WeakPolarHBondContact O-CB 3.43Å; I538-L542 WeakPolarHBondContact O-CG 3.48Å; I538-L542 PolarHBondContact O-N 3.33Å; L542-N544 VanDerWaalsContact C-N 3.26Å; L542-N544 PolarHBondContact O-N 3.17Å; L542-N544 VanDerWaalsContact O-N 3.11Å; L542-I545 HydrophobicContact CD2-CD1 4.1Å; L542-I545 WeakPolarHBondContact O-CA 3.34Å; L542-I545 WeakPolarHBondContact O-CB 3.14Å; L542-I545 PolarHBondContact O-N 2.72Å; L542-L546 WeakPolarHBondContact O-CG 3.37Å; L542-L546 PolarHBondContact O-N 3.32Å
543K90.2Very high92.4Very high36 Ų3619.2 Ų19.216%0.15710%0.096CC..Hα-helixtrans-50.3-43.7-17384.1-176.2-165.8170.20113.6Q539 M540 L547 K682Q539-K543 PolarHBondContact O-N 2.97Å; Q539-K543 VanDerWaalsContact O-N 3.11Å; M540-K543 WeakPolarHBondContact O-CG 3.3Å; K543-L547 PolarHBondContact O-N 3.11Å; K543-K682 VanDerWaalsContact CD-O 3.29Å; K543-K682 WeakPolarHBondContact CD-O 3.23Å; K543-K682 PolarHBondContact NZ-O 3.25Å
544N90.2Very high92.6Very high24 Ų2415.5 Ų15.513%0.1288%0.081CC..Hα-helixtrans-73.5-41.5-179.3-67.9-25.5000110.4L542 L546 L547 M548L542-N544 VanDerWaalsContact C-N 3.26Å; L542-N544 PolarHBondContact O-N 3.17Å; L542-N544 VanDerWaalsContact O-N 3.11Å; N544-L546 VanDerWaalsContact C-N 3.3Å; N544-L546 PolarHBondContact O-N 3.43Å; N544-L547 WeakPolarHBondContact O-CB 3.41Å; N544-L547 PolarHBondContact O-N 2.65Å; N544-L547 VanDerWaalsContact O-N 3.12Å; N544-M548 HydrophobicContact CB-SD 4.29Å; N544-M548 WeakPolarHBondContact O-CB 3.28Å; N544-M548 WeakPolarHBondContact O-CG 3.34Å; N544-M548 PolarHBondContact O-N 3.18Å
545I94.6Very high92.8Very high0 Ų018.2 Ų18.20%010%0.099CC..Hα-helixtrans-61.5-39.3178.7-65.9164.3000111I476 L479 K480 L483 F505 L542 M548 F549I476-I545 HydrophobicContact CG2-CD1 3.57Å; I476-I545 VanDerWaalsContact O-CD1 3.25Å; I476-I545 WeakPolarHBondContact O-CD1 3.29Å; L479-I545 HydrophobicContact CB-CD1 4.27Å; L479-I545 HydrophobicContact CD2-CG2 3.97Å; L479-I545 HydrophobicContact CG-CD1 4.38Å; L479-I545 HydrophobicContact CG-CG2 4.07Å; K480-I545 HydrophobicContact CB-CD1 4.09Å; K480-I545 HydrophobicContact CB-CG1 3.9Å; K480-I545 HydrophobicContact CG-CG1 4.31Å; L483-I545 HydrophobicContact CD1-CG2 4Å; F505-I545 HydrophobicContact CE1-CG2 4.41Å; F505-I545 HydrophobicContact CE2-CG2 3.91Å; F505-I545 HydrophobicContact CZ-CG2 3.74Å; L542-I545 HydrophobicContact CD2-CD1 4.1Å; L542-I545 WeakPolarHBondContact O-CA 3.34Å; L542-I545 WeakPolarHBondContact O-CB 3.14Å; L542-I545 PolarHBondContact O-N 2.72Å; I545-M548 PolarHBondContact O-N 2.93Å; I545-F549 HydrophobicContact CG2-CD2 3.68Å; I545-F549 HydrophobicContact CG2-CE2 3.63Å; I545-F549 WeakPolarHBondContact O-CD2 3.46Å; I545-F549 PolarHBondContact O-N 3.13Å
546L94.9Very high92.9Very high1 Ų119.4 Ų19.41%0.00511%0.105CC..Hα-helixtrans-58-47.2172.8-66.3174.1000111.6F505 L509 L542 N544 Q550 P610F505-L546 HydrophobicContact CE1-CD2 3.91Å; F505-L546 HydrophobicContact CZ-CD2 3.89Å; L509-L546 HydrophobicContact CD1-CD2 3.68Å; L509-L546 HydrophobicContact CD2-CD2 3.96Å; L509-L546 HydrophobicContact CG-CD2 4.47Å; L542-L546 WeakPolarHBondContact O-CG 3.37Å; L542-L546 PolarHBondContact O-N 3.32Å; N544-L546 VanDerWaalsContact C-N 3.3Å; N544-L546 PolarHBondContact O-N 3.43Å; L546-Q550 WeakPolarHBondContact O-CG 3.49Å; L546-Q550 PolarHBondContact O-N 3.24Å; L546-Q550 PolarHBondContact O-NE2 3.11Å; L546-P610 HydrophobicContact CD1-CB 4.34Å
547L92.3Very high93.1Very high33 Ų3322.9 Ų22.917%0.17312%0.121CC..Hα-helixtrans-65.7-43.3177179.463.6000111.8K543 N544 Q550 E551 R621 E794K543-L547 PolarHBondContact O-N 3.11Å; N544-L547 WeakPolarHBondContact O-CB 3.41Å; N544-L547 PolarHBondContact O-N 2.65Å; N544-L547 VanDerWaalsContact O-N 3.12Å; L547-Q550 CarbonylContact O-C 3.49Å; L547-Q550 WeakPolarHBondContact O-CA 3.43Å; L547-Q550 WeakPolarHBondContact O-CB 3.48Å; L547-Q550 PolarHBondContact O-N 2.95Å; L547-Q550 VanDerWaalsContact O-N 3.13Å; L547-E551 HydrophobicContact CD1-CG 4.45Å; L547-E551 PolarHBondContact O-N 2.93Å; L547-R621 VanDerWaalsContact CD1-NH2 3.32Å; L547-E794 HydrophobicContact CD2-CG 4.46Å
548M94.1Very high93.2Very high1 Ų125.8 Ų25.81%0.00513%0.131CC..Hα-helixtrans-63.1-45.9-179-67.7163.293.600111.2K480 L483 I484 N544 I545 Q550 E551 W552 E794K480-M548 HydrophobicContact CG-CE 4.16Å; K480-M548 HydrophobicContact CG-SD 3.79Å; K480-M548 WeakPolarHBondContact O-CE 3.48Å; L483-M548 VanDerWaalsContact C-CE 3.42Å; L483-M548 HydrophobicContact CB-CB 4.06Å; L483-M548 HydrophobicContact CB-CE 3.84Å; L483-M548 HydrophobicContact CB-SD 4.44Å; L483-M548 HydrophobicContact CD1-CB 4.33Å; L483-M548 WeakPolarHBondContact O-CE 3.36Å; I484-M548 HydrophobicContact CB-CE 4.36Å; I484-M548 HydrophobicContact CG1-CE 3.8Å; N544-M548 HydrophobicContact CB-SD 4.29Å; N544-M548 WeakPolarHBondContact O-CB 3.28Å; N544-M548 WeakPolarHBondContact O-CG 3.34Å; N544-M548 PolarHBondContact O-N 3.18Å; I545-M548 PolarHBondContact O-N 2.93Å; M548-Q550 VanDerWaalsContact C-N 3.31Å; M548-Q550 PolarHBondContact O-N 2.77Å; M548-E551 PolarHBondContact O-N 3Å; M548-E551 VanDerWaalsContact O-N 3.17Å; M548-W552 PolarHBondContact O-N 3.44Å; M548-E794 HydrophobicContact CG-CG 3.9Å; M548-E794 VanDerWaalsContact CG-OE1 3.26Å; M548-E794 WeakPolarHBondContact CG-OE1 3.44Å; M548-E794 HydrophobicContact SD-CG 4.23Å
549F96.6Very high93.4Very high1 Ų125.7 Ų25.70%0.00413%0.13CC..Hα-helixtrans-58.6-40.8172-86.5-65000112.1I438 L479 L483 F498 F502 F505 I545 W552 C553I438-F549 HydrophobicContact CG2-CE1 4.23Å; I438-F549 HydrophobicContact CG2-CZ 3.95Å; L479-F549 HydrophobicContact CD1-CE2 4.44Å; L479-F549 HydrophobicContact CD1-CZ 4.24Å; L479-F549 HydrophobicContact CD2-CE2 4.34Å; L483-F549 HydrophobicContact CD1-CD1 4.41Å; L483-F549 HydrophobicContact CD1-CD2 3.84Å; L483-F549 HydrophobicContact CD1-CE1 4.26Å; L483-F549 HydrophobicContact CD1-CE2 3.66Å; L483-F549 HydrophobicContact CD1-CG 4.22Å; L483-F549 HydrophobicContact CD1-CZ 3.89Å; L483-F549 HydrophobicContact CD2-CD1 4.41Å; L483-F549 HydrophobicContact CD2-CE1 4.18Å; L483-F549 HydrophobicContact CD2-CZ 4.47Å; F498-F549 AromaticContact CE2-CD1 3.75Å; F498-F549 HydrophobicContact CE2-CD1 3.75Å; F498-F549 AromaticContact CE2-CE1 3.91Å; F498-F549 HydrophobicContact CE2-CE1 3.91Å; F498-F549 AromaticContact CZ-CD1 3.76Å; F498-F549 HydrophobicContact CZ-CD1 3.76Å; F498-F549 HydrophobicContact CZ-CE1 4.27Å; F502-F549 HydrophobicContact CB-CD1 4.41Å; F502-F549 HydrophobicContact CB-CE1 4.19Å; F502-F549 HydrophobicContact CD2-CB 4.23Å; F502-F549 AromaticContact CD2-CD1 3.57Å; F502-F549 HydrophobicContact CD2-CD1 3.57Å; F502-F549 AromaticContact CD2-CE1 3.99Å; F502-F549 HydrophobicContact CD2-CE1 3.99Å; F502-F549 AromaticContact CD2-CG 3.93Å; F502-F549 HydrophobicContact CD2-CG 3.93Å; F502-F549 HydrophobicContact CE2-CB 4.16Å; F502-F549 HydrophobicContact CE2-CD1 4.34Å; F502-F549 HydrophobicContact CE2-CG 4.3Å; F502-F549 HydrophobicContact CG-CD1 4.41Å; F505-F549 HydrophobicContact CB-CE2 4Å; F505-F549 HydrophobicContact CB-CZ 3.98Å; F505-F549 AromaticContact CD1-CD2 3.47Å; F505-F549 HydrophobicContact CD1-CD2 3.47Å; F505-F549 VanDerWaalsContact CD1-CD2 3.47Å; F505-F549 AromaticContact CD1-CE2 3.35Å; F505-F549 HydrophobicContact CD1-CE2 3.35Å; F505-F549 HydrophobicContact CD1-CG 4.28Å; F505-F549 HydrophobicContact CD1-CZ 4.08Å; F505-F549 AromaticContact CD2-CE2 3.87Å; F505-F549 HydrophobicContact CD2-CE2 3.87Å; F505-F549 AromaticContact CE1-CD2 3.45Å; F505-F549 HydrophobicContact CE1-CD2 3.45Å; F505-F549 VanDerWaalsContact CE1-CD2 3.45Å; F505-F549 AromaticContact CE1-CE2 3.66Å; F505-F549 HydrophobicContact CE1-CE2 3.66Å; F505-F549 HydrophobicContact CE1-CG 4.41Å; F505-F549 HydrophobicContact CE2-CE2 4.16Å; F505-F549 HydrophobicContact CG-CD2 4.09Å; F505-F549 AromaticContact CG-CE2 3.46Å; F505-F549 HydrophobicContact CG-CE2 3.46Å; F505-F549 VanDerWaalsContact CG-CE2 3.46Å; F505-F549 AromaticContact CG-CZ 3.97Å; F505-F549 HydrophobicContact CG-CZ 3.97Å; F505-F549 HydrophobicContact CZ-CD2 4.07Å; F505-F549 HydrophobicContact CZ-CE2 4.07Å; I545-F549 HydrophobicContact CG2-CD2 3.68Å; I545-F549 HydrophobicContact CG2-CE2 3.63Å; I545-F549 WeakPolarHBondContact O-CD2 3.46Å; I545-F549 PolarHBondContact O-N 3.13Å; F549-W552 PolarHBondContact O-N 2.87Å; F549-C553 WeakPolarHBondContact O-CB 3.44Å; F549-C553 PolarHBondContact O-N 3.06Å; F549-C553 PolarHBondContact O-SG 3.33Å
550Q95.4Very high93.7Very high2 Ų225.5 Ų25.51%0.00913%0.129CC..Hα-helixtrans-65.4-37.9175.4-65.9163.149.700112.5L546 L547 M548 A554 L618 E686L546-Q550 WeakPolarHBondContact O-CG 3.49Å; L546-Q550 PolarHBondContact O-N 3.24Å; L546-Q550 PolarHBondContact O-NE2 3.11Å; L547-Q550 CarbonylContact O-C 3.49Å; L547-Q550 WeakPolarHBondContact O-CA 3.43Å; L547-Q550 WeakPolarHBondContact O-CB 3.48Å; L547-Q550 PolarHBondContact O-N 2.95Å; L547-Q550 VanDerWaalsContact O-N 3.13Å; M548-Q550 VanDerWaalsContact C-N 3.31Å; M548-Q550 PolarHBondContact O-N 2.77Å; Q550-A554 VanDerWaalsContact O-CB 3.28Å; Q550-A554 WeakPolarHBondContact O-CB 3.3Å; Q550-A554 PolarHBondContact O-N 3.32Å; Q550-A554 VanDerWaalsContact O-N 3.14Å; Q550-L618 HydrophobicContact CB-CD2 4.33Å; Q550-L618 HydrophobicContact CG-CD2 4.06Å; Q550-L618 HydrophobicContact CG-CG 4.35Å; Q550-E686 PolarHBondContact NE2-OE2 3.22Å
551E92.9Very high94.1Very high26 Ų2622.7 Ų22.712%0.12112%0.115CC..Hα-helixtrans-70.1-41.5175.3-70.6-133.9159.900112K486 L547 M548 A554 C555 K764K486-E551 IonicContact NZ-OE2 2.6Å; K486-E551 PolarHBondContact NZ-OE2 3.19Å; L547-E551 HydrophobicContact CD1-CG 4.45Å; L547-E551 PolarHBondContact O-N 2.93Å; M548-E551 PolarHBondContact O-N 3Å; M548-E551 VanDerWaalsContact O-N 3.17Å; E551-A554 CarbonylContact O-C 3.55Å; E551-A554 PolarHBondContact O-N 2.95Å; E551-C555 PolarHBondContact O-N 3.13Å; E551-C555 PolarHBondContact O-SG 3.17Å; E551-K764 IonicContact OE1-NZ 3.17Å; E551-K764 PolarHBondContact OE1-NZ 3.31Å
552W95.1Very high94.4Very high4 Ų420.1 Ų20.12%0.01511%0.105CC..Hα-helixtrans-62-48.3174.8-85.962.1000112I432 L483 K486 P487 W490 F498 M548 F549 A554 C555I432-W552 HydrophobicContact CD1-CH2 3.43Å; I432-W552 VanDerWaalsContact CD1-CH2 3.43Å; I432-W552 HydrophobicContact CD1-CZ2 4.47Å; I432-W552 HydrophobicContact CD1-CZ3 3.85Å; L483-W552 HydrophobicContact CD2-CD2 4.17Å; L483-W552 HydrophobicContact CD2-CG 4.48Å; L483-W552 HydrophobicContact CD2-CZ2 4.29Å; L483-W552 PolarHBondContact O-NE1 3.25Å; K486-W552 HydrophobicContact CB-CD2 4.47Å; K486-W552 HydrophobicContact CB-CG 4.41Å; P487-W552 VanDerWaalsContact CD-CE3 3.49Å; P487-W552 VanDerWaalsContact CD-CZ3 3.44Å; P487-W552 HydrophobicContact CG-CE3 4Å; P487-W552 HydrophobicContact CG-CH2 4.4Å; P487-W552 HydrophobicContact CG-CZ3 3.87Å; W490-W552 AromaticContact CH2-CE3 3.86Å; W490-W552 HydrophobicContact CH2-CE3 3.86Å; W490-W552 HydrophobicContact CH2-CZ3 4.36Å; W490-W552 HydrophobicContact CZ2-CE3 4.22Å; F498-W552 HydrophobicContact CD2-CD2 4.28Å; F498-W552 AromaticContact CD2-CE3 3.45Å; F498-W552 HydrophobicContact CD2-CE3 3.45Å; F498-W552 VanDerWaalsContact CD2-CE3 3.45Å; F498-W552 AromaticContact CD2-CZ3 3.95Å; F498-W552 HydrophobicContact CD2-CZ3 3.95Å; F498-W552 HydrophobicContact CE1-CB 4.5Å; F498-W552 HydrophobicContact CE2-CB 3.63Å; F498-W552 AromaticContact CE2-CD2 3.86Å; F498-W552 HydrophobicContact CE2-CD2 3.86Å; F498-W552 AromaticContact CE2-CE3 3.48Å; F498-W552 HydrophobicContact CE2-CE3 3.48Å; F498-W552 VanDerWaalsContact CE2-CE3 3.48Å; F498-W552 AromaticContact CE2-CG 3.97Å; F498-W552 HydrophobicContact CE2-CG 3.97Å; F498-W552 HydrophobicContact CE2-CZ3 4.36Å; F498-W552 HydrophobicContact CG-CE3 4.31Å; F498-W552 HydrophobicContact CZ-CB 3.53Å; F498-W552 HydrophobicContact CZ-CE3 4.36Å; F498-W552 HydrophobicContact CZ-CG 4.37Å; M548-W552 PolarHBondContact O-N 3.44Å; F549-W552 PolarHBondContact O-N 2.87Å; W552-A554 PolarHBondContact O-N 3.2Å; W552-C555 WeakPolarHBondContact O-CB 3.37Å; W552-C555 PolarHBondContact O-N 3.26Å
553C95.9Very high94.7Very high0 Ų019.9 Ų19.90%010%0.104CC..Hα-helixtrans-55.6-43.1174.1-66.60000110.4F549 C555 D556 L560 A563 L618F549-C553 WeakPolarHBondContact O-CB 3.44Å; F549-C553 PolarHBondContact O-N 3.06Å; F549-C553 PolarHBondContact O-SG 3.33Å; C553-C555 PolarHBondContact O-N 3.28Å; C553-C555 VanDerWaalsContact O-N 3.12Å; C553-D556 PolarHBondContact O-N 2.69Å; C553-L560 HydrophobicContact CB-CD1 3.62Å; C553-L560 WeakPolarHBondContact O-CB 3.46Å; C553-A563 HydrophobicContact CB-CB 4.26Å; C553-A563 VanDerWaalsContact SG-CB 3.5Å; C553-L618 HydrophobicContact CB-CD2 3.95Å
554A94.3Very high95Very high10 Ų1018.2 Ų18.28%0.08310%0.097CC..THydrogen-bonded Turntrans-72.93.6-179.800000115.7Q550 E551 W552 L560 R621Q550-A554 VanDerWaalsContact O-CB 3.28Å; Q550-A554 WeakPolarHBondContact O-CB 3.3Å; Q550-A554 PolarHBondContact O-N 3.32Å; Q550-A554 VanDerWaalsContact O-N 3.14Å; E551-A554 CarbonylContact O-C 3.55Å; E551-A554 PolarHBondContact O-N 2.95Å; W552-A554 PolarHBondContact O-N 3.2Å; A554-L560 HydrophobicContact CB-CD2 4.49Å; A554-R621 HydrophobicContact CB-CB 3.89Å; A554-R621 HydrophobicContact CB-CG 3.95Å
555C94.2Very high95.4Very high57 Ų5720.1 Ų20.139%0.38510%0.104SC..THydrogen-bonded Turntrans-86.3-12172.3-64.30000113.2W490 E551 W552 C553W490-C555 HydrophobicContact CZ2-CB 4.47Å; E551-C555 PolarHBondContact O-N 3.13Å; E551-C555 PolarHBondContact O-SG 3.17Å; W552-C555 WeakPolarHBondContact O-CB 3.37Å; W552-C555 PolarHBondContact O-N 3.26Å; C553-C555 PolarHBondContact O-N 3.28Å; C553-C555 VanDerWaalsContact O-N 3.12Å
556D93.7Very high95.5Very high25 Ų2521.8 Ų21.813%0.13411%0.112CC..SBendtrans-145.1126.6177.4178.8-70.3000109.5W490 R495 C553 E558 L559 L560W490-D556 HydrophobicContact CG-CB 4.32Å; R495-D556 IonicContact CZ-OD2 3.49Å; R495-D556 IonicContact NE-OD1 2.83Å; R495-D556 IonicContact NE-OD2 3.51Å; R495-D556 PolarHBondContact NE-OD2 3.48Å; R495-D556 IonicContact NH2-OD2 3.27Å; R495-D556 PolarHBondContact NH2-OD2 3.37Å; C553-D556 PolarHBondContact O-N 2.69Å; D556-E558 PolarHBondContact OD1-N 2.86Å; D556-L559 HydrophobicContact CB-CB 3.76Å; D556-L559 HydrophobicContact CB-CD2 4.26Å; D556-L559 WeakPolarHBondContact OD1-CB 3.4Å; D556-L559 PolarHBondContact OD1-N 3.42Å; D556-L560 WeakPolarHBondContact O-CB 3.44Å; D556-L560 PolarHBondContact O-N 3.09Å
557E94.4Very high95.7Very high79 Ų7921.7 Ų21.737%0.36911%0.111SC..Hα-helixtrans-66.4-42.3-170.7-174.5-176.6115.600112.8L560 L561 A627 R630E557-L560 PolarHBondContact O-N 3.09Å; E557-L561 HydrophobicContact CG-CD1 4.15Å; E557-L561 WeakPolarHBondContact O-CG 3.33Å; E557-L561 PolarHBondContact O-N 3.44Å; E557-A627 HydrophobicContact CG-CB 3.74Å; E557-R630 WeakPolarHBondContact OE1-CD 3.38Å; E557-R630 IonicContact OE1-CZ 2.71Å; E557-R630 IonicContact OE1-NE 2.71Å; E557-R630 IonicContact OE1-NH1 2.69Å; E557-R630 PolarHBondContact OE1-NH1 3.34Å
558E93.8Very high95.9Very high87 Ų8720.5 Ų20.541%0.40711%0.105SC..Hα-helixtrans-70-41.1-178-168.867.9-170.500110D556 L560 L561 V562 R630 F634D556-E558 PolarHBondContact OD1-N 2.86Å; E558-L560 VanDerWaalsContact C-N 3.33Å; E558-L560 PolarHBondContact O-N 3.22Å; E558-L561 PolarHBondContact O-N 2.99Å; E558-V562 WeakPolarHBondContact O-CG2 3.19Å; E558-V562 PolarHBondContact O-N 2.96Å; E558-R630 IonicContact OE2-CZ 2.85Å; E558-R630 IonicContact OE2-NH1 3.47Å; E558-R630 PolarHBondContact OE2-NH1 2.9Å; E558-R630 IonicContact OE2-NH2 3.91Å; E558-R630 PolarHBondContact OE2-NH2 3.18Å; E558-F634 VanDerWaalsContact OE1-CZ 3.29Å; E558-F634 WeakPolarHBondContact OE1-CZ 3.36Å
559L95.4Very high95.9Very high3 Ų324.1 Ų24.12%0.01612%0.12CC..Hα-helixtrans-55.9-46.4170.5176.265.6000111.9W490 F498 L499 D556 L561 V562 A563W490-L559 HydrophobicContact CD2-CD2 4.5Å; W490-L559 HydrophobicContact CE3-CD2 4.43Å; W490-L559 HydrophobicContact CH2-CD2 3.31Å; W490-L559 HydrophobicContact CZ2-CD2 3.38Å; W490-L559 HydrophobicContact CZ3-CD2 3.87Å; F498-L559 HydrophobicContact CD1-CD1 3.73Å; F498-L559 HydrophobicContact CD1-CD2 3.95Å; F498-L559 HydrophobicContact CD1-CG 4.36Å; F498-L559 HydrophobicContact CE1-CD1 4Å; F498-L559 HydrophobicContact CE1-CD2 3.9Å; F498-L559 HydrophobicContact CE1-CG 4.27Å; L499-L559 HydrophobicContact CD1-CD1 3.92Å; L499-L559 HydrophobicContact CD2-CD1 3.55Å; L499-L559 HydrophobicContact CG-CD1 3.43Å; L499-L559 VanDerWaalsContact CG-CD1 3.43Å; D556-L559 HydrophobicContact CB-CB 3.76Å; D556-L559 HydrophobicContact CB-CD2 4.26Å; D556-L559 WeakPolarHBondContact OD1-CB 3.4Å; D556-L559 PolarHBondContact OD1-N 3.42Å; L559-L561 PolarHBondContact O-N 2.9Å; L559-V562 PolarHBondContact O-N 2.92Å; L559-A563 VanDerWaalsContact O-CB 3.24Å; L559-A563 WeakPolarHBondContact O-CB 3.44Å; L559-A563 PolarHBondContact O-N 3.32Å
560L97Very high95.9Very high0 Ų024.3 Ų24.30%012%0.122CC..Hα-helixtrans-62.4-41.2179.4-176.559.4000112.3C553 A554 D556 E557 E558 A563 Y564 L618 R621 L622 L625C553-L560 HydrophobicContact CB-CD1 3.62Å; C553-L560 WeakPolarHBondContact O-CB 3.46Å; A554-L560 HydrophobicContact CB-CD2 4.49Å; D556-L560 WeakPolarHBondContact O-CB 3.44Å; D556-L560 PolarHBondContact O-N 3.09Å; E557-L560 PolarHBondContact O-N 3.09Å; E558-L560 VanDerWaalsContact C-N 3.33Å; E558-L560 PolarHBondContact O-N 3.22Å; L560-A563 PolarHBondContact O-N 2.93Å; L560-Y564 WeakPolarHBondContact O-CB 3.44Å; L560-Y564 PolarHBondContact O-N 3.29Å; L560-L618 HydrophobicContact CD1-CB 4.41Å; L560-L618 HydrophobicContact CD1-CD2 3.73Å; L560-R621 HydrophobicContact CD1-CB 4.22Å; L560-R621 HydrophobicContact CD2-CB 3.9Å; L560-L622 HydrophobicContact CB-CD2 4.39Å; L560-L622 HydrophobicContact CD2-CB 4.43Å; L560-L622 HydrophobicContact CD2-CD2 3.66Å; L560-L622 HydrophobicContact CD2-CG 3.84Å; L560-L622 HydrophobicContact CG-CD2 3.66Å; L560-L622 HydrophobicContact CG-CG 3.9Å; L560-L625 HydrophobicContact CD2-CD1 3.83Å
561L97.4Very high95.9Very high0 Ų024.2 Ų24.20%012%0.122CC..Hα-helixtrans-65.9-42.6177.8-73.7161.5000111.7E557 E558 L559 K565 L622 R630 L631 F634E557-L561 HydrophobicContact CG-CD1 4.15Å; E557-L561 WeakPolarHBondContact O-CG 3.33Å; E557-L561 PolarHBondContact O-N 3.44Å; E558-L561 PolarHBondContact O-N 2.99Å; L559-L561 PolarHBondContact O-N 2.9Å; L561-K565 PolarHBondContact O-N 3.17Å; L561-K565 VanDerWaalsContact O-N 3.08Å; L561-L622 HydrophobicContact CD2-CD2 3.62Å; L561-L622 HydrophobicContact CG-CD2 3.92Å; L561-R630 HydrophobicContact CD1-CB 4.11Å; L561-R630 HydrophobicContact CD2-CB 4.4Å; L561-L631 HydrophobicContact CD2-CD1 4.45Å; L561-F634 HydrophobicContact CB-CD1 3.97Å; L561-F634 HydrophobicContact CB-CD2 3.79Å; L561-F634 HydrophobicContact CB-CE1 3.88Å; L561-F634 HydrophobicContact CB-CE2 3.73Å; L561-F634 HydrophobicContact CB-CG 3.95Å; L561-F634 HydrophobicContact CB-CZ 3.76Å; L561-F634 HydrophobicContact CD1-CD2 4.26Å; L561-F634 HydrophobicContact CD1-CE2 3.68Å; L561-F634 HydrophobicContact CD1-CZ 4.1Å; L561-F634 HydrophobicContact CD2-CD2 3.98Å; L561-F634 HydrophobicContact CD2-CE2 4.25Å; L561-F634 HydrophobicContact CG-CD2 4.23Å; L561-F634 HydrophobicContact CG-CE2 4.09Å; L561-F634 HydrophobicContact CG-CZ 4.49Å
562V97.4Very high95.8Very high29 Ų2924.2 Ų24.218%0.17612%0.122CC..Hα-helixtrans-66.7-43.7174.41770000111.5L499 E558 L559 Y564 K565 E566 F634L499-V562 HydrophobicContact CD1-CB 4.36Å; L499-V562 HydrophobicContact CD1-CG1 3.8Å; L499-V562 HydrophobicContact CD2-CB 4.37Å; L499-V562 HydrophobicContact CD2-CG1 3.89Å; E558-V562 WeakPolarHBondContact O-CG2 3.19Å; E558-V562 PolarHBondContact O-N 2.96Å; L559-V562 PolarHBondContact O-N 2.92Å; V562-Y564 PolarHBondContact O-N 2.82Å; V562-K565 WeakPolarHBondContact O-CB 3.46Å; V562-K565 PolarHBondContact O-N 3.49Å; V562-E566 PolarHBondContact O-N 3.25Å; V562-F634 HydrophobicContact CG2-CD1 4.21Å; V562-F634 HydrophobicContact CG2-CE1 3.8Å
563A98Very high95.6Very high0 Ų032.1 Ų32.10%015%0.152CC..Hα-helixtrans-61.6-42.4176.700000111.8L499 F502 C553 L559 L560 K565 E566 C567L499-A563 HydrophobicContact CD2-CB 4.42Å; F502-A563 HydrophobicContact CD1-CB 4.01Å; F502-A563 HydrophobicContact CE1-CB 3.68Å; F502-A563 HydrophobicContact CZ-CB 4.42Å; C553-A563 HydrophobicContact CB-CB 4.26Å; C553-A563 VanDerWaalsContact SG-CB 3.5Å; L559-A563 VanDerWaalsContact O-CB 3.24Å; L559-A563 WeakPolarHBondContact O-CB 3.44Å; L559-A563 PolarHBondContact O-N 3.32Å; L560-A563 PolarHBondContact O-N 2.93Å; A563-K565 PolarHBondContact O-N 2.81Å; A563-E566 PolarHBondContact O-N 3.4Å; A563-C567 WeakPolarHBondContact O-CB 3.45Å; A563-C567 PolarHBondContact O-N 3.1Å
564Y97.9Very high95.2Very high0 Ų032.9 Ų32.90%016%0.157CC..Hα-helixtrans-59.2-45.4174.2-170-81.6000111.7L560 V562 C567 H568 L615 L618 H619 L622 L631 F640L560-Y564 WeakPolarHBondContact O-CB 3.44Å; L560-Y564 PolarHBondContact O-N 3.29Å; V562-Y564 PolarHBondContact O-N 2.82Å; Y564-C567 PolarHBondContact O-N 2.88Å; Y564-H568 HydrophobicContact CE1-CB 4.41Å; Y564-H568 VanDerWaalsContact O-CB 3.32Å; Y564-H568 WeakPolarHBondContact O-CB 3.47Å; Y564-H568 PolarHBondContact O-N 2.8Å; Y564-L615 HydrophobicContact CD1-CD1 4.08Å; Y564-L615 HydrophobicContact CD2-CD1 3.83Å; Y564-L615 HydrophobicContact CE1-CD1 3.81Å; Y564-L615 HydrophobicContact CE2-CD1 3.49Å; Y564-L615 VanDerWaalsContact CE2-CD1 3.49Å; Y564-L615 HydrophobicContact CE2-CG 4Å; Y564-L615 HydrophobicContact CG-CD1 4.11Å; Y564-L615 VanDerWaalsContact CZ-CD1 3.5Å; Y564-L618 HydrophobicContact CD2-CB 3.77Å; Y564-L618 HydrophobicContact CE2-CB 4.44Å; Y564-H619 HydrophobicContact CE2-CB 3.78Å; Y564-H619 AromaticContact CE2-ND1 3.81Å; Y564-H619 AromaticContact CZ-ND1 3.74Å; Y564-H619 PolarHBondContact OH-ND1 3.03Å; Y564-L622 HydrophobicContact CD1-CD1 4.43Å; Y564-L622 HydrophobicContact CD2-CD1 3.49Å; Y564-L622 VanDerWaalsContact CD2-CD1 3.49Å; Y564-L622 HydrophobicContact CE2-CD1 4.05Å; Y564-L622 HydrophobicContact CG-CD1 3.71Å; Y564-L631 HydrophobicContact CD1-CD1 3.4Å; Y564-L631 HydrophobicContact CD1-CD2 4.35Å; Y564-L631 HydrophobicContact CD1-CG 4.48Å; Y564-L631 HydrophobicContact CE1-CD1 3.72Å; Y564-L631 HydrophobicContact CE1-CD2 3.87Å; Y564-L631 HydrophobicContact CE1-CG 4.36Å; Y564-L631 HydrophobicContact CG-CD1 4.08Å; Y564-F640 AromaticContact CE1-CE2 3.99Å; Y564-F640 HydrophobicContact CE1-CE2 3.99Å
565K97.6Very high94.6Very high64 Ų6432.4 Ų32.428%0.27815%0.153SC..Hα-helixtrans-59.7-45.4177.2-179.7-179.2-172.61430112.6L561 V562 A563 H568 K569 F634 V635L561-K565 PolarHBondContact O-N 3.17Å; L561-K565 VanDerWaalsContact O-N 3.08Å; V562-K565 WeakPolarHBondContact O-CB 3.46Å; V562-K565 PolarHBondContact O-N 3.49Å; A563-K565 PolarHBondContact O-N 2.81Å; K565-H568 PolarHBondContact O-N 2.96Å; K565-K569 VanDerWaalsContact O-CG 3.3Å; K565-K569 WeakPolarHBondContact O-CG 3.33Å; K565-K569 PolarHBondContact O-N 3.29Å; K565-F634 HydrophobicContact CB-CB 4.25Å; K565-F634 HydrophobicContact CD-CB 4.14Å; K565-F634 HydrophobicContact CD-CD1 4.39Å; K565-F634 WeakPolarHBondContact CD-O 3.45Å; K565-F634 WeakPolarHBondContact CE-O 3.41Å; K565-F634 PolarHBondContact NZ-O 3.49Å; K565-V635 HydrophobicContact CB-CG2 4.16Å; K565-V635 HydrophobicContact CG-CG2 4.18Å
566E97.9Very high93.3Very high35 Ų3533.8 Ų33.816%0.16416%0.16CC..Hα-helixtrans-69.4-37.4178.5-62.7-50.5124.400112.1R503 L506 V562 A563 K569 A570R503-E566 HydrophobicContact CG-CB 4.38Å; R503-E566 HydrophobicContact CG-CG 4.22Å; L506-E566 HydrophobicContact CD1-CB 4.05Å; V562-E566 PolarHBondContact O-N 3.25Å; A563-E566 PolarHBondContact O-N 3.4Å; E566-K569 IonicContact OE1-NZ 2.67Å; E566-K569 PolarHBondContact OE1-NZ 3.31Å; E566-K569 IonicContact OE2-NZ 2.9Å; E566-A570 PolarHBondContact O-N 3.17Å; E566-A570 VanDerWaalsContact O-N 3.09Å
567C98Very high91.7Very high0 Ų036.7 Ų36.70%018%0.182CC..Hα-helixtrans-64.8-43.4173.3-168.40000111.9L506 A563 Y564 A570 V571 L615 L618L506-C567 HydrophobicContact CD1-CB 4.33Å; L506-C567 HydrophobicContact CD2-CB 4.16Å; A563-C567 WeakPolarHBondContact O-CB 3.45Å; A563-C567 PolarHBondContact O-N 3.1Å; Y564-C567 PolarHBondContact O-N 2.88Å; C567-A570 PolarHBondContact O-N 3.29Å; C567-V571 WeakPolarHBondContact O-CG2 3.42Å; C567-V571 PolarHBondContact O-N 3.14Å; C567-L615 HydrophobicContact CB-CD1 4.01Å; C567-L618 HydrophobicContact CB-CD1 3.89Å
568H96.8Very high89.9Confident8 Ų833.7 Ų33.74%0.03717%0.168CC..Hα-helixtrans-60.3-49.1176.2173.6-89.5000111.2Y564 K565 A570 V571 M572 L615 V635 D639 F640Y564-H568 HydrophobicContact CE1-CB 4.41Å; Y564-H568 VanDerWaalsContact O-CB 3.32Å; Y564-H568 WeakPolarHBondContact O-CB 3.47Å; Y564-H568 PolarHBondContact O-N 2.8Å; K565-H568 PolarHBondContact O-N 2.96Å; H568-A570 PolarHBondContact O-N 3.28Å; H568-V571 PolarHBondContact O-N 2.99Å; H568-V571 VanDerWaalsContact O-N 3.14Å; H568-M572 VanDerWaalsContact CE1-CG 3.44Å; H568-M572 WeakPolarHBondContact CE1-CG 3.45Å; H568-M572 WeakPolarHBondContact O-CG 3.31Å; H568-M572 PolarHBondContact O-N 3.08Å; H568-L615 HydrophobicContact CB-CD1 4.02Å; H568-L615 HydrophobicContact CB-CD2 4.47Å; H568-V635 HydrophobicContact CB-CG2 4.37Å; H568-D639 PolarHBondContact CE1-O 3.29Å; H568-F640 PolarHBondContact NE2-O 2.94Å; H568-F640 VanDerWaalsContact NE2-O 3.07Å
569K95.3Very high88.2Confident76 Ų7633.7 Ų33.733%0.3317%0.17SC..Hα-helixtrans-53.8-41.6173.5-74.3168.5177.41750112.3K565 E566 M572 R573K565-K569 VanDerWaalsContact O-CG 3.3Å; K565-K569 WeakPolarHBondContact O-CG 3.33Å; K565-K569 PolarHBondContact O-N 3.29Å; E566-K569 IonicContact OE1-NZ 2.67Å; E566-K569 PolarHBondContact OE1-NZ 3.31Å; E566-K569 IonicContact OE2-NZ 2.9Å; K569-M572 PolarHBondContact O-N 2.83Å; K569-R573 VanDerWaalsContact O-CG 3.27Å; K569-R573 WeakPolarHBondContact O-CG 3.48Å; K569-R573 PolarHBondContact O-N 3.08Å
570A95.7Very high86.2Confident5 Ų538.7 Ų38.74%0.04121%0.205CC..Hα-helixtrans-67-44.5178.400000111.8E566 C567 H568 M572 R573 C574 L611E566-A570 PolarHBondContact O-N 3.17Å; E566-A570 VanDerWaalsContact O-N 3.09Å; C567-A570 PolarHBondContact O-N 3.29Å; H568-A570 PolarHBondContact O-N 3.28Å; A570-M572 VanDerWaalsContact C-N 3.35Å; A570-M572 PolarHBondContact O-N 3.01Å; A570-R573 WeakPolarHBondContact O-CB 3.32Å; A570-R573 PolarHBondContact O-N 3.09Å; A570-C574 PolarHBondContact O-N 3.47Å; A570-C574 VanDerWaalsContact O-N 3.08Å; A570-C574 PolarHBondContact O-SG 2.83Å; A570-L611 HydrophobicContact CB-CD1 3.97Å; A570-L611 HydrophobicContact CB-CD2 3.87Å; A570-L611 HydrophobicContact CB-CG 4.41Å
571V94.7Very high84.6Confident1 Ų141 Ų411%0.00622%0.221CC..Hα-helixtrans-57.9-46.5173173.50000111.2C567 H568 R573 C574 S575 L611 L615 L645C567-V571 WeakPolarHBondContact O-CG2 3.42Å; C567-V571 PolarHBondContact O-N 3.14Å; H568-V571 PolarHBondContact O-N 2.99Å; H568-V571 VanDerWaalsContact O-N 3.14Å; V571-R573 VanDerWaalsContact C-N 3.32Å; V571-R573 PolarHBondContact O-N 2.93Å; V571-C574 PolarHBondContact O-N 3.44Å; V571-S575 WeakPolarHBondContact O-CB 3.35Å; V571-S575 PolarHBondContact O-N 2.86Å; V571-S575 PolarHBondContact O-OG 2.9Å; V571-L611 HydrophobicContact CG2-CD2 4.27Å; V571-L611 HydrophobicContact CG2-CG 3.78Å; V571-L615 HydrophobicContact CB-CD2 4.46Å; V571-L615 HydrophobicContact CG2-CB 4.29Å; V571-L615 HydrophobicContact CG2-CD2 4.07Å; V571-L645 HydrophobicContact CG1-CD2 3.73Å
572M92.1Very high83.3Confident25 Ų2545.1 Ų45.112%0.12325%0.25CC..Hα-helixtrans-64.2-36.5179.8-66.5-50.9-65.400112H568 K569 A570 S575 T576 Q641 V644 L645H568-M572 VanDerWaalsContact CE1-CG 3.44Å; H568-M572 WeakPolarHBondContact CE1-CG 3.45Å; H568-M572 WeakPolarHBondContact O-CG 3.31Å; H568-M572 PolarHBondContact O-N 3.08Å; K569-M572 PolarHBondContact O-N 2.83Å; A570-M572 VanDerWaalsContact C-N 3.35Å; A570-M572 PolarHBondContact O-N 3.01Å; M572-S575 CarbonylContact O-C 3.35Å; M572-S575 PolarHBondContact O-N 3.27Å; M572-T576 WeakPolarHBondContact O-CG2 3.44Å; M572-T576 PolarHBondContact O-N 3.07Å; M572-Q641 HydrophobicContact CE-CB 3.7Å; M572-Q641 HydrophobicContact CE-CG 4.07Å; M572-Q641 VanDerWaalsContact CE-OE1 3.23Å; M572-Q641 HydrophobicContact SD-CB 4.42Å; M572-V644 HydrophobicContact CE-CB 4.17Å; M572-V644 HydrophobicContact CE-CG1 4.02Å; M572-V644 HydrophobicContact CE-CG2 4.42Å; M572-V644 HydrophobicContact SD-CB 4.37Å; M572-V644 HydrophobicContact SD-CG1 4.12Å; M572-L645 HydrophobicContact SD-CD2 3.88Å
573R90.3Very high82.6Confident171 Ų17149.9 Ų49.965%0.64527%0.268SS*.Hα-helixtrans-61.3-48.5172.4-76169.9-175.7171.61.8112.1K569 A570 V571 S575 T576K569-R573 VanDerWaalsContact O-CG 3.27Å; K569-R573 WeakPolarHBondContact O-CG 3.48Å; K569-R573 PolarHBondContact O-N 3.08Å; A570-R573 WeakPolarHBondContact O-CB 3.32Å; A570-R573 PolarHBondContact O-N 3.09Å; V571-R573 VanDerWaalsContact C-N 3.32Å; V571-R573 PolarHBondContact O-N 2.93Å; R573-S575 PolarHBondContact O-N 2.77Å; R573-T576 WeakPolarHBondContact O-CB 3.31Å; R573-T576 WeakPolarHBondContact O-CG2 3.43Å; R573-T576 PolarHBondContact O-N 3.21Å; R573-T576 VanDerWaalsContact O-N 3.14Å; R573-T576 PolarHBondContact O-OG1 3.42Å
574C88.5Confident81.8Confident15 Ų1552.4 Ų52.410%0.10128%0.284CS..Hα-helixtrans-58.3-35.2174.9-63.30000112.1Q513 A570 V571 T576Q513-C574 HydrophobicContact CG-CB 3.96Å; A570-C574 PolarHBondContact O-N 3.47Å; A570-C574 VanDerWaalsContact O-N 3.08Å; A570-C574 PolarHBondContact O-SG 2.83Å; V571-C574 PolarHBondContact O-N 3.44Å; C574-T576 VanDerWaalsContact C-N 3.28Å; C574-T576 PolarHBondContact O-N 3.21Å
575S81.8Confident81.3Confident1 Ų156.4 Ų56.41%0.00731%0.308CS..THydrogen-bonded Turntrans-81.11.2-178.9-50.70000114.2V571 M572 R573 S577 F578V571-S575 WeakPolarHBondContact O-CB 3.35Å; V571-S575 PolarHBondContact O-N 2.86Å; V571-S575 PolarHBondContact O-OG 2.9Å; M572-S575 CarbonylContact O-C 3.35Å; M572-S575 PolarHBondContact O-N 3.27Å; R573-S575 PolarHBondContact O-N 2.77Å; S575-S577 PolarHBondContact O-N 2.74Å; S575-F578 VanDerWaalsContact O-CB 3.3Å; S575-F578 WeakPolarHBondContact O-CB 3.3Å; S575-F578 PolarHBondContact O-N 3.22Å; S575-F578 VanDerWaalsContact O-N 3.12Å
576T65.5Low80.7Confident86 Ų8654.2 Ų54.253%0.52830%0.3SS..Hα-helixtrans-65.5-35.2-177.750.70000113.7M572 R573 C574 F578 I579M572-T576 WeakPolarHBondContact O-CG2 3.44Å; M572-T576 PolarHBondContact O-N 3.07Å; R573-T576 WeakPolarHBondContact O-CB 3.31Å; R573-T576 WeakPolarHBondContact O-CG2 3.43Å; R573-T576 PolarHBondContact O-N 3.21Å; R573-T576 VanDerWaalsContact O-N 3.14Å; R573-T576 PolarHBondContact O-OG1 3.42Å; C574-T576 VanDerWaalsContact C-N 3.28Å; C574-T576 PolarHBondContact O-N 3.21Å; T576-F578 PolarHBondContact O-N 2.86Å; T576-I579 WeakPolarHBondContact O-CB 3.41Å; T576-I579 PolarHBondContact O-N 3.22Å
577S60.1Low80.2Confident86 Ų8658.8 Ų58.860%0.60132%0.321SS*.Hα-helixtrans-60.2-32.3173.358.30000112S575 I579S575-S577 PolarHBondContact O-N 2.74Å; S577-I579 VanDerWaalsContact C-N 3.28Å; S577-I579 PolarHBondContact O-N 3.4Å
578F56.9Low79.6Confident16 Ų1659.4 Ų59.47%0.0733%0.326CS..Hα-helixtrans-69.7-22.4173.4-176.1-123.6000111.8S575 T576 S580 K596 E647 R651S575-F578 VanDerWaalsContact O-CB 3.3Å; S575-F578 WeakPolarHBondContact O-CB 3.3Å; S575-F578 PolarHBondContact O-N 3.22Å; S575-F578 VanDerWaalsContact O-N 3.12Å; T576-F578 PolarHBondContact O-N 2.86Å; F578-S580 PolarHBondContact O-N 3.21Å; F578-K596 HydrophobicContact CD2-CB 4.47Å; F578-K596 HydrophobicContact CD2-CD 4.19Å; F578-K596 HydrophobicContact CE1-CD 4.31Å; F578-K596 HydrophobicContact CE1-CG 4.3Å; F578-K596 HydrophobicContact CE2-CB 3.59Å; F578-K596 HydrophobicContact CE2-CD 3.99Å; F578-K596 HydrophobicContact CE2-CG 4Å; F578-K596 HydrophobicContact CG-CD 4.45Å; F578-K596 HydrophobicContact CZ-CB 3.72Å; F578-K596 HydrophobicContact CZ-CD 4.05Å; F578-K596 HydrophobicContact CZ-CG 3.78Å; F578-K596 WeakPolarHBondContact O-CD 3.46Å; F578-K596 WeakPolarHBondContact O-CE 3.38Å; F578-K596 PolarHBondContact O-NZ 3Å; F578-E647 HydrophobicContact CD1-CG 4.47Å; F578-E647 HydrophobicContact CE1-CB 4.48Å; F578-E647 HydrophobicContact CE1-CG 3.64Å; F578-E647 VanDerWaalsContact CZ-CD 3.5Å; F578-E647 HydrophobicContact CZ-CG 3.9Å; F578-R651 VanDerWaalsContact CZ-NH2 3.34Å
579I57.9Low78.9Confident86 Ų8662 Ų6244%0.44134%0.344SS..Hα-helixtrans-71.2-27.6-172.6-62.8176.5000113T576 S577T576-I579 WeakPolarHBondContact O-CB 3.41Å; T576-I579 PolarHBondContact O-N 3.22Å; S577-I579 VanDerWaalsContact C-N 3.28Å; S577-I579 PolarHBondContact O-N 3.4Å
580S54.4Low78.5Confident109 Ų10962.5 Ų62.576%0.76237%0.37SS*.THydrogen-bonded Turntrans-943.4-168.860.60000116.9F578F578-S580 PolarHBondContact O-N 3.21Å
581S62.2Low78.3Confident48 Ų4864.6 Ų64.634%0.33638%0.38SS..SBendtrans-88167.3-174.667.40000114.9K596S581-K596 VanDerWaalsContact OG-CD 3.29Å; S581-K596 WeakPolarHBondContact OG-CD 3.42Å
582S71.6Confident78.1Confident86 Ų8667.7 Ų67.760%0.60140%0.401SS*.PPolyproline II helixtrans-63.3143.4178540000112.2S597S582-S597 PolarHBondContact O-N 3.12Å
583K81.3Confident78Confident130 Ų13066.7 Ų66.757%0.56540%0.396SS*.EExtended strand (participates in β ladder)trans-101.4146.9-178.9-59-173.4-174.9-173.60112.1E594K583-E594 HydrophobicContact CB-CG 4.26Å; K583-E594 HydrophobicContact CD-CG 3.87Å; K583-E594 WeakPolarHBondContact CD-OE1 3.3Å; K583-E594 WeakPolarHBondContact CE-OE1 3.5Å; K583-E594 IonicContact NZ-OE1 2.68Å; K583-E594 PolarHBondContact NZ-OE1 3.12Å
584T82.2Confident77.8Confident52 Ų5263.5 Ų63.532%0.31939%0.388SS..EExtended strand (participates in β ladder)trans-122.7131.4178.2-53.20000108.4T595 S597T584-T595 PolarHBondContact N-O 3.23Å; T584-T595 PolarHBondContact O-N 3.44Å; T584-T595 VanDerWaalsContact O-N 3.15Å; T584-S597 WeakPolarHBondContact OG1-CB 3.39Å
585V86Confident77.5Confident84 Ų8463.1 Ų63.151%0.50939%0.386SS..EExtended strand (participates in β ladder)trans-97.1122.4175.6-177.30000109Q587 L593 E594V585-Q587 HydrophobicContact CG1-CG 3.97Å; V585-L593 WeakPolarHBondContact CA-O 3.37Å; V585-E594 HydrophobicContact CG2-CB 4.32Å; V585-E594 HydrophobicContact CG2-CG 4.14Å
586V85.8Confident77.3Confident18 Ų1864.2 Ų64.211%0.10939%0.39CS..EExtended strand (participates in β ladder)trans-106.6134.3169.6175.10000108.7S592 L593 L709 Q713 A718V586-S592 WeakPolarHBondContact O-CA 3.31Å; V586-L593 PolarHBondContact N-O 3.14Å; V586-L593 PolarHBondContact O-N 3.38Å; V586-L709 HydrophobicContact CG1-CD2 4.18Å; V586-Q713 HydrophobicContact CG2-CB 4.28Å; V586-Q713 VanDerWaalsContact CG2-CD 3.44Å; V586-Q713 HydrophobicContact CG2-CG 4Å; V586-A718 HydrophobicContact CG1-CB 3.95Å
587Q86.9Confident78.1Confident132 Ų13262.7 Ų62.762%0.61738%0.384SS*.EExtended strand (participates in β ladder)trans-127136.3178.5-58.5-172.2-15.500109.9V585 H591 N722V585-Q587 HydrophobicContact CG1-CG 3.97Å; Q587-H591 WeakPolarHBondContact CA-O 3.25Å; Q587-N722 PolarHBondContact O-ND2 3.49Å
588S85.6Confident79.5Confident13 Ų1359.8 Ų59.89%0.09136%0.36CS..EExtended strand (participates in β ladder)trans-159.4149.3168.5-161.70000110.1G590 H591 N722 Y889S588-G590 PolarHBondContact O-N 3.35Å; S588-H591 PolarHBondContact N-O 2.9Å; S588-H591 PolarHBondContact O-N 3.23Å; S588-H591 VanDerWaalsContact O-O 3.14Å; S588-N722 WeakPolarHBondContact CB-OD1 3.41Å; S588-N722 PolarHBondContact OG-OD1 3.47Å; S588-Y889 WeakPolarHBondContact OG-CE1 3.48Å
589C82.9Confident81.2Confident62 Ų6263.7 Ų63.742%0.41937%0.374SS..THydrogen-bonded Turntrans50.328.2179.5-58.30000116.2H591 I886 Y889C589-H591 VanDerWaalsContact C-N 3.25Å; C589-H591 PolarHBondContact O-CD2 3.21Å; C589-H591 PolarHBondContact O-N 2.89Å; C589-I886 HydrophobicContact CB-CD1 3.93Å; C589-Y889 WeakPolarHBondContact SG-CB 3.47Å
590G85.5Confident82.9Confident86 Ų8659.6 Ų59.689%0.88735%0.353SS*.THydrogen-bonded Turntrans81.7-3.8-176.200000114.9S588S588-G590 PolarHBondContact O-N 3.35Å
591H91.8Very high84.8Confident50 Ų5054.7 Ų54.723%0.23132%0.318CS..EExtended strand (participates in β ladder)trans-94.3148.3173.9-62-76.7000110.6Q587 S588 C589 N705 L709 D885Q587-H591 WeakPolarHBondContact CA-O 3.25Å; S588-H591 PolarHBondContact N-O 2.9Å; S588-H591 PolarHBondContact O-N 3.23Å; S588-H591 VanDerWaalsContact O-O 3.14Å; C589-H591 VanDerWaalsContact C-N 3.25Å; C589-H591 PolarHBondContact O-CD2 3.21Å; C589-H591 PolarHBondContact O-N 2.89Å; H591-N705 HydrophobicContact CB-CB 4.12Å; H591-N705 PolarHBondContact CE1-ND2 2.94Å; H591-L709 HydrophobicContact CB-CD1 4.03Å; H591-D885 IonicContact CD2-OD2 2.92Å; H591-D885 IonicContact CE1-OD2 3.95Å; H591-D885 IonicContact NE2-OD2 2.63Å; H591-D885 PolarHBondContact NE2-OD2 2.96Å
592S91.4Very high86.2Confident65 Ų6556.7 Ų56.746%0.45532%0.322SS..EExtended strand (participates in β ladder)trans-132.7139.6176.761.90000112V586V586-S592 WeakPolarHBondContact O-CA 3.31Å
593L89.3Confident87.2Confident4 Ų455.2 Ų55.22%0.02131%0.308CS..EExtended strand (participates in β ladder)trans-121.3129.1170178.967.8000108.8V585 V586 T595 K706 L709 L710V585-L593 WeakPolarHBondContact CA-O 3.37Å; V586-L593 PolarHBondContact N-O 3.14Å; V586-L593 PolarHBondContact O-N 3.38Å; L593-T595 HydrophobicContact CD2-CG2 3.73Å; L593-T595 HydrophobicContact CG-CG2 4.04Å; L593-K706 HydrophobicContact CD1-CB 4.29Å; L593-K706 HydrophobicContact CD1-CG 4.46Å; L593-L709 HydrophobicContact CB-CB 3.97Å; L593-L709 HydrophobicContact CB-CD1 4.07Å; L593-L709 HydrophobicContact CD2-CB 4.11Å; L593-L710 HydrophobicContact CD2-CB 3.63Å; L593-L710 HydrophobicContact CD2-CD1 4.12Å; L593-L710 HydrophobicContact CD2-CG 4.46Å
594E86.7Confident87.8Confident104 Ų10452.9 Ų52.949%0.48630%0.301SS..EExtended strand (participates in β ladder)trans-105.297.7169.4-176.3-167.7150.400107.5K583 V585K583-E594 HydrophobicContact CB-CG 4.26Å; K583-E594 HydrophobicContact CD-CG 3.87Å; K583-E594 WeakPolarHBondContact CD-OE1 3.3Å; K583-E594 WeakPolarHBondContact CE-OE1 3.5Å; K583-E594 IonicContact NZ-OE1 2.68Å; K583-E594 PolarHBondContact NZ-OE1 3.12Å; V585-E594 HydrophobicContact CG2-CB 4.32Å; V585-E594 HydrophobicContact CG2-CG 4.14Å
595T81.9Confident88.3Confident8 Ų850.6 Ų50.65%0.04929%0.287CS..EExtended strand (participates in β ladder)trans-126.6172.9177.6-176.10000109.8T584 L593 L710 Q713 R714T584-T595 PolarHBondContact N-O 3.23Å; T584-T595 PolarHBondContact O-N 3.44Å; T584-T595 VanDerWaalsContact O-N 3.15Å; L593-T595 HydrophobicContact CD2-CG2 3.73Å; L593-T595 HydrophobicContact CG-CG2 4.04Å; T595-L710 HydrophobicContact CG2-CD1 3.95Å; T595-Q713 VanDerWaalsContact CG2-CD 3.41Å; T595-R714 PolarHBondContact OG1-NH2 3.27Å; T595-R714 VanDerWaalsContact OG1-NH2 3.11Å
596K77.8Confident88.7Confident23 Ų2347 Ų4710%0.127%0.265CS..EExtended strand (participates in β ladder)trans-79.8149.7-171-47.4-153.9-166.488.60112.2F578 S581 Y598 R714F578-K596 HydrophobicContact CD2-CB 4.47Å; F578-K596 HydrophobicContact CD2-CD 4.19Å; F578-K596 HydrophobicContact CE1-CD 4.31Å; F578-K596 HydrophobicContact CE1-CG 4.3Å; F578-K596 HydrophobicContact CE2-CB 3.59Å; F578-K596 HydrophobicContact CE2-CD 3.99Å; F578-K596 HydrophobicContact CE2-CG 4Å; F578-K596 HydrophobicContact CG-CD 4.45Å; F578-K596 HydrophobicContact CZ-CB 3.72Å; F578-K596 HydrophobicContact CZ-CD 4.05Å; F578-K596 HydrophobicContact CZ-CG 3.78Å; F578-K596 WeakPolarHBondContact O-CD 3.46Å; F578-K596 WeakPolarHBondContact O-CE 3.38Å; F578-K596 PolarHBondContact O-NZ 3Å; S581-K596 VanDerWaalsContact OG-CD 3.29Å; S581-K596 WeakPolarHBondContact OG-CD 3.42Å; K596-Y598 PolarHBondContact O-N 2.7Å; K596-Y598 VanDerWaalsContact O-N 3.13Å; K596-R714 PolarHBondContact O-NH1 2.81Å; K596-R714 PolarHBondContact O-NH2 3Å; K596-R714 VanDerWaalsContact O-NH2 3.07Å
597S82.2Confident89.1Confident55 Ų5546.2 Ų46.239%0.38526%0.261SS..  trans-65.9109.8169.3-171.40000108.2S582 T584S582-S597 PolarHBondContact O-N 3.12Å; T584-S597 WeakPolarHBondContact OG1-CB 3.39Å
598Y88.7Confident89.5Confident25 Ų2540 Ų4010%0.09823%0.231CC..  trans-156.1127.8173.1-179.7-81.1000107.5K596 V600 D603 L604 R651 R714K596-Y598 PolarHBondContact O-N 2.7Å; K596-Y598 VanDerWaalsContact O-N 3.13Å; Y598-V600 HydrophobicContact CD1-CG2 4.48Å; Y598-V600 HydrophobicContact CE1-CG2 3.77Å; Y598-D603 VanDerWaalsContact CA-OD2 3.31Å; Y598-D603 WeakPolarHBondContact CA-OD2 3.25Å; Y598-D603 HydrophobicContact CD2-CB 3.86Å; Y598-D603 HydrophobicContact CE1-CB 4.44Å; Y598-D603 HydrophobicContact CE2-CB 3.48Å; Y598-D603 VanDerWaalsContact CE2-CB 3.48Å; Y598-L604 PolarHBondContact OH-O 2.89Å; Y598-R651 HydrophobicContact CD1-CG 4.06Å; Y598-R651 HydrophobicContact CE1-CB 4.34Å; Y598-R651 VanDerWaalsContact CE1-CD 3.42Å; Y598-R651 HydrophobicContact CE1-CG 3.5Å; Y598-R651 VanDerWaalsContact CE1-CG 3.5Å; Y598-R714 PolarHBondContact O-NH1 3.27Å
599R92.4Very high90Very high98 Ų9839.4 Ų39.437%0.3723%0.227SC..  trans-128.5114.9-176.4-67179.766.5-154.5-7.1108.7S601 E602 D603 E716R599-S601 PolarHBondContact O-N 3.09Å; R599-S601 VanDerWaalsContact O-N 3.12Å; R599-E602 HydrophobicContact CB-CB 4.35Å; R599-E602 VanDerWaalsContact CZ-CD 3.46Å; R599-E602 IonicContact CZ-OE1 3.33Å; R599-E602 IonicContact CZ-OE2 2.66Å; R599-E602 IonicContact NE-OE2 3.72Å; R599-E602 IonicContact NH1-OE1 2.67Å; R599-E602 PolarHBondContact NH1-OE1 3.12Å; R599-E602 IonicContact NH1-OE2 3.44Å; R599-E602 PolarHBondContact NH1-OE2 3.2Å; R599-E602 IonicContact NH2-OE1 3.79Å; R599-E602 PolarHBondContact O-N 2.79Å; R599-D603 PolarHBondContact N-OD2 3.12Å; R599-D603 WeakPolarHBondContact O-CB 3.43Å; R599-D603 PolarHBondContact O-N 3.23Å; R599-E716 IonicContact CZ-OE2 2.68Å; R599-E716 IonicContact NE-OE2 3.32Å; R599-E716 PolarHBondContact NE-OE2 2.91Å; R599-E716 IonicContact NH2-OE2 2.66Å; R599-E716 PolarHBondContact NH2-OE2 3.37Å
600V94.3Very high90.6Very high0 Ų036.5 Ų36.50%021%0.208CC..THydrogen-bonded Turntrans-58.7-30.1-179.4176.80000111Y598 E602 V605 R651 V654 L655 W664Y598-V600 HydrophobicContact CD1-CG2 4.48Å; Y598-V600 HydrophobicContact CE1-CG2 3.77Å; V600-E602 PolarHBondContact O-N 3.42Å; V600-V605 HydrophobicContact CG1-CG1 4.39Å; V600-R651 HydrophobicContact CG2-CB 4.05Å; V600-R651 HydrophobicContact CG2-CG 4.15Å; V600-V654 HydrophobicContact CB-CB 4.43Å; V600-V654 HydrophobicContact CB-CG1 3.67Å; V600-V654 HydrophobicContact CG1-CG1 3.98Å; V600-V654 HydrophobicContact CG2-CB 3.97Å; V600-V654 HydrophobicContact CG2-CG1 3.66Å; V600-L655 HydrophobicContact CG1-CB 3.99Å; V600-W664 HydrophobicContact CG1-CZ2 4.23Å; V600-W664 VanDerWaalsContact O-CZ2 3.24Å; V600-W664 WeakPolarHBondContact O-CZ2 3.25Å
601S94.3Very high91.1Very high5 Ų532.4 Ų32.44%0.03517%0.165CC..THydrogen-bonded Turntrans-72-5.9177.8670000115.5R520 R599 Q658 E716R520-S601 WeakPolarHBondContact CD-O 2.99Å; R599-S601 PolarHBondContact O-N 3.09Å; R599-S601 VanDerWaalsContact O-N 3.12Å; S601-Q658 VanDerWaalsContact CA-OE1 3.32Å; S601-E716 WeakPolarHBondContact CB-OE1 3.49Å; S601-E716 PolarHBondContact N-OE1 3.42Å; S601-E716 PolarHBondContact OG-OE1 3.23Å; S601-E716 PolarHBondContact OG-OE2 2.87Å
602E92.7Very high91.3Very high91 Ų9130 Ų3043%0.42515%0.154SC..THydrogen-bonded Turntrans-134.9-29.5-174.8-67.7-177.8164.500114.6R519 R599 V600R519-E602 PolarHBondContact NE-O 3.08Å; R519-E602 PolarHBondContact NH2-O 3.38Å; R599-E602 HydrophobicContact CB-CB 4.35Å; R599-E602 VanDerWaalsContact CZ-CD 3.46Å; R599-E602 IonicContact CZ-OE1 3.33Å; R599-E602 IonicContact CZ-OE2 2.66Å; R599-E602 IonicContact NE-OE2 3.72Å; R599-E602 IonicContact NH1-OE1 2.67Å; R599-E602 PolarHBondContact NH1-OE1 3.12Å; R599-E602 IonicContact NH1-OE2 3.44Å; R599-E602 PolarHBondContact NH1-OE2 3.2Å; R599-E602 IonicContact NH2-OE1 3.79Å; R599-E602 PolarHBondContact O-N 2.79Å; V600-E602 PolarHBondContact O-N 3.42Å
603D92.5Very high91.6Very high55 Ų5527 Ų2729%0.29413%0.133SC..SBendtrans-93.6173.3-176-67.1-48.9000113Y598 R599Y598-D603 VanDerWaalsContact CA-OD2 3.31Å; Y598-D603 WeakPolarHBondContact CA-OD2 3.25Å; Y598-D603 HydrophobicContact CD2-CB 3.86Å; Y598-D603 HydrophobicContact CE1-CB 4.44Å; Y598-D603 HydrophobicContact CE2-CB 3.48Å; Y598-D603 VanDerWaalsContact CE2-CB 3.48Å; R599-D603 PolarHBondContact N-OD2 3.12Å; R599-D603 WeakPolarHBondContact O-CB 3.43Å; R599-D603 PolarHBondContact O-N 3.23Å
604L92.1Very high92Very high81 Ų8126.9 Ų26.942%0.42413%0.133SC..  trans-76.3131.7175.6-77.1169.8000111.2E517 I518 R519 Y598E517-L604 HydrophobicContact CB-CB 4Å; E517-L604 HydrophobicContact CB-CD2 4Å; E517-L604 HydrophobicContact CB-CG 4.45Å; I518-L604 WeakPolarHBondContact O-CA 3.25Å; R519-L604 HydrophobicContact CB-CD2 3.99Å; Y598-L604 PolarHBondContact OH-O 2.89Å
605V93.6Very high92.5Very high4 Ų421.9 Ų21.92%0.02411%0.109CC..BIsolated β-bridgetrans-139.9151.9-178.460.70000110.7E517 I518 V600 R651 L655 W664E517-V605 CarbonylContact C-O 3.57Å; E517-V605 WeakPolarHBondContact CA-O 3.18Å; I518-V605 HydrophobicContact CG1-CG1 3.96Å; I518-V605 WeakPolarHBondContact CG1-O 3.3Å; I518-V605 PolarHBondContact N-O 3.2Å; I518-V605 PolarHBondContact O-N 3.23Å; V600-V605 HydrophobicContact CG1-CG1 4.39Å; V605-R651 HydrophobicContact CG2-CB 4.12Å; V605-L655 HydrophobicContact CG1-CB 4.48Å; V605-L655 HydrophobicContact CG1-CD1 4.07Å; V605-L655 HydrophobicContact CG1-CD2 3.98Å; V605-L655 HydrophobicContact CG1-CG 4.4Å; V605-L655 HydrophobicContact CG2-CB 4.18Å; V605-L655 HydrophobicContact CG2-CD2 4.12Å; V605-W664 HydrophobicContact CG1-CH2 3.76Å; V605-W664 HydrophobicContact CG1-CZ2 4.26Å
606S93.8Very high93.3Very high8 Ų821.5 Ų21.56%0.05611%0.107CC..  trans-141.3149.1177.3169.40000111.2M515 H608M515-S606 VanDerWaalsContact O-CB 3.29Å; M515-S606 WeakPolarHBondContact O-CB 3.49Å; M515-S606 PolarHBondContact O-OG 2.94Å; S606-H608 PolarHBondContact OG-N 3.19Å
607I94.9Very high94.2Very high1 Ų120.5 Ų20.51%0.00510%0.103CC..SBendtrans-86.5-8.2172.764.6156.8000113.2I536 L609 R613 L655 Q674 M687I536-I607 HydrophobicContact CD1-CD1 4.19Å; I607-L609 PolarHBondContact O-N 2.67Å; I607-R613 VanDerWaalsContact O-CZ 3.29Å; I607-R613 PolarHBondContact O-NH1 3.24Å; I607-R613 PolarHBondContact O-NH2 3.49Å; I607-L655 HydrophobicContact CG2-CD2 3.86Å; I607-Q674 HydrophobicContact CD1-CB 3.73Å; I607-Q674 HydrophobicContact CD1-CG 4.35Å; I607-Q674 WeakPolarHBondContact CD1-O 3.29Å; I607-M687 HydrophobicContact CD1-CE 4.26Å
608H95.1Very high95Very high1 Ų118 Ų181%0.0059%0.085CC..  trans-92.887.9-174.1-62-79000110.8G514 M515 S606 P610G514-H608 PolarHBondContact N-O 3Å; M515-H608 HydrophobicContact CE-CB 3.77Å; M515-H608 VanDerWaalsContact CE-CG 3.48Å; M515-H608 VanDerWaalsContact CE-ND1 3.3Å; M515-H608 WeakPolarHBondContact CE-ND1 3.35Å; M515-H608 HydrophobicContact CG-CB 3.58Å; M515-H608 HydrophobicContact SD-CB 4.38Å; S606-H608 PolarHBondContact OG-N 3.19Å; H608-P610 WeakPolarHBondContact O-CD 3.41Å
609L95.9Very high95.4Very high1 Ų116.9 Ų16.91%0.0058%0.081CC..  trans-121.741.7-172.9-50.1174.9000113.8Q513 I607 L611 S612 R613 Y648 C652Q513-L609 VanDerWaalsContact OE1-CA 3.32Å; Q513-L609 PolarHBondContact OE1-O 3.33Å; I607-L609 PolarHBondContact O-N 2.67Å; L609-L611 PolarHBondContact O-N 3.29Å; L609-L611 VanDerWaalsContact O-N 3.17Å; L609-S612 PolarHBondContact O-N 3.28Å; L609-R613 VanDerWaalsContact O-CG 3.27Å; L609-R613 WeakPolarHBondContact O-CG 3.24Å; L609-R613 PolarHBondContact O-N 3.38Å; L609-R613 VanDerWaalsContact O-N 3.09Å; L609-Y648 WeakPolarHBondContact CD1-O 3.45Å; L609-Y648 HydrophobicContact CD2-CD1 3.69Å; L609-Y648 HydrophobicContact CD2-CG 4.14Å; L609-C652 HydrophobicContact CD1-CB 3.83Å
610P96.2Very high95.6Very high1 Ų112.4 Ų12.41%0.0067%0.065CC..Hα-helixtrans-63.5-27.9-16827.9-36.3000113.5L509 M512 L546 H608 R613 T614L509-P610 HydrophobicContact CD2-CB 4.24Å; L509-P610 HydrophobicContact CD2-CG 4.35Å; M512-P610 HydrophobicContact CB-CG 3.47Å; M512-P610 VanDerWaalsContact CB-CG 3.47Å; M512-P610 HydrophobicContact CE-CG 4.15Å; M512-P610 HydrophobicContact CG-CG 4.35Å; M512-P610 HydrophobicContact SD-CG 3.99Å; L546-P610 HydrophobicContact CD1-CB 4.34Å; H608-P610 WeakPolarHBondContact O-CD 3.41Å; P610-R613 PolarHBondContact O-N 2.94Å; P610-T614 WeakPolarHBondContact O-CB 3.45Å; P610-T614 PolarHBondContact O-N 3.14Å; P610-T614 PolarHBondContact O-OG1 3.34Å
611L95.6Very high95.8Very high0 Ų013.7 Ų13.70%07%0.07CC..Hα-helixtrans-72.5-44.8179.8-174.164.7000111.6L506 L509 Q513 A570 V571 L609 R613 T614 L615L506-L611 HydrophobicContact CD2-CD1 3.55Å; L509-L611 HydrophobicContact CB-CB 4.12Å; L509-L611 HydrophobicContact CB-CD1 3.98Å; L509-L611 HydrophobicContact CD1-CD1 4.43Å; Q513-L611 HydrophobicContact CB-CB 3.95Å; Q513-L611 HydrophobicContact CB-CD2 4.3Å; Q513-L611 HydrophobicContact CG-CB 4.17Å; Q513-L611 HydrophobicContact CG-CD2 4.42Å; A570-L611 HydrophobicContact CB-CD1 3.97Å; A570-L611 HydrophobicContact CB-CD2 3.87Å; A570-L611 HydrophobicContact CB-CG 4.41Å; V571-L611 HydrophobicContact CG2-CD2 4.27Å; V571-L611 HydrophobicContact CG2-CG 3.78Å; L609-L611 PolarHBondContact O-N 3.29Å; L609-L611 VanDerWaalsContact O-N 3.17Å; L611-R613 VanDerWaalsContact C-N 3.29Å; L611-R613 PolarHBondContact O-N 2.83Å; L611-T614 PolarHBondContact O-N 2.85Å; L611-L615 PolarHBondContact O-N 3.12Å
612S96.1Very high95.9Very high0 Ų013.5 Ų13.50%07%0.068CC..Hα-helixtrans-60.1-41.1171.8-64.30000111.6Q513 L609 L615 A616 M694Q513-S612 PolarHBondContact NE2-OG 3.42Å; Q513-S612 VanDerWaalsContact OE1-N 3.12Å; L609-S612 PolarHBondContact O-N 3.28Å; S612-L615 WeakPolarHBondContact O-CB 3.25Å; S612-L615 PolarHBondContact O-N 3.15Å; S612-A616 PolarHBondContact O-N 3.27Å; S612-A616 VanDerWaalsContact O-N 3.13Å; S612-M694 WeakPolarHBondContact O-CE 3.41Å
613R97.2Very high96.1Very high1 Ų19.7 Ų9.70%0.0045%0.052CC..Hα-helixtrans-71.5-34.1-178.8-66.1177.9-174.4142.23.5112.9I607 L609 P610 L611 L615 A616 G617 E686 M687 K690 D691I607-R613 VanDerWaalsContact O-CZ 3.29Å; I607-R613 PolarHBondContact O-NH1 3.24Å; I607-R613 PolarHBondContact O-NH2 3.49Å; L609-R613 VanDerWaalsContact O-CG 3.27Å; L609-R613 WeakPolarHBondContact O-CG 3.24Å; L609-R613 PolarHBondContact O-N 3.38Å; L609-R613 VanDerWaalsContact O-N 3.09Å; P610-R613 PolarHBondContact O-N 2.94Å; L611-R613 VanDerWaalsContact C-N 3.29Å; L611-R613 PolarHBondContact O-N 2.83Å; R613-L615 VanDerWaalsContact C-N 3.35Å; R613-A616 PolarHBondContact O-N 3.46Å; R613-G617 PolarHBondContact O-N 2.94Å; R613-E686 WeakPolarHBondContact CD-O 3.41Å; R613-M687 PolarHBondContact NE-O 3.43Å; R613-K690 HydrophobicContact CB-CB 3.58Å; R613-K690 HydrophobicContact CB-CG 4.02Å; R613-K690 HydrophobicContact CG-CB 3.6Å; R613-D691 WeakPolarHBondContact CG-OD1 3.23Å; R613-D691 IonicContact CZ-OD1 2.88Å; R613-D691 IonicContact CZ-OD2 2.75Å; R613-D691 IonicContact NE-OD1 3.31Å; R613-D691 PolarHBondContact NE-OD1 2.75Å; R613-D691 IonicContact NE-OD2 3.94Å; R613-D691 PolarHBondContact NE-OD2 3.3Å; R613-D691 IonicContact NH2-OD1 2.75Å; R613-D691 PolarHBondContact NH2-OD1 2.93Å; R613-D691 IonicContact NH2-OD2 3.2Å; R613-D691 PolarHBondContact NH2-OD2 3.23Å
614T97.8Very high96.1Very high2 Ų212.2 Ų12.21%0.0126%0.057CC..Hα-helixtrans-59.6-45.5169.3-58.50000110.8L509 P610 L611 A616 G617 L618L509-T614 WeakPolarHBondContact CD1-OG1 3.39Å; P610-T614 WeakPolarHBondContact O-CB 3.45Å; P610-T614 PolarHBondContact O-N 3.14Å; P610-T614 PolarHBondContact O-OG1 3.34Å; L611-T614 PolarHBondContact O-N 2.85Å; T614-A616 VanDerWaalsContact C-N 3.34Å; T614-A616 PolarHBondContact O-N 2.94Å; T614-G617 PolarHBondContact O-N 3.11Å; T614-G617 VanDerWaalsContact O-N 3.17Å; T614-L618 HydrophobicContact CG2-CD1 4.18Å; T614-L618 HydrophobicContact CG2-CG 4.43Å; T614-L618 WeakPolarHBondContact O-CG 3.45Å; T614-L618 PolarHBondContact O-N 2.8Å
615L97.9Very high96.2Very high0 Ų011.9 Ų11.90%06%0.055CC..Hα-helixtrans-61.8-40.6177.9-170.568.4000112.2Y564 C567 H568 V571 L611 S612 R613 L618 H619 L645 M694Y564-L615 HydrophobicContact CD1-CD1 4.08Å; Y564-L615 HydrophobicContact CD2-CD1 3.83Å; Y564-L615 HydrophobicContact CE1-CD1 3.81Å; Y564-L615 HydrophobicContact CE2-CD1 3.49Å; Y564-L615 VanDerWaalsContact CE2-CD1 3.49Å; Y564-L615 HydrophobicContact CE2-CG 4Å; Y564-L615 HydrophobicContact CG-CD1 4.11Å; Y564-L615 VanDerWaalsContact CZ-CD1 3.5Å; C567-L615 HydrophobicContact CB-CD1 4.01Å; H568-L615 HydrophobicContact CB-CD1 4.02Å; H568-L615 HydrophobicContact CB-CD2 4.47Å; V571-L615 HydrophobicContact CB-CD2 4.46Å; V571-L615 HydrophobicContact CG2-CB 4.29Å; V571-L615 HydrophobicContact CG2-CD2 4.07Å; L611-L615 PolarHBondContact O-N 3.12Å; S612-L615 WeakPolarHBondContact O-CB 3.25Å; S612-L615 PolarHBondContact O-N 3.15Å; R613-L615 VanDerWaalsContact C-N 3.35Å; L615-L618 PolarHBondContact O-N 2.74Å; L615-H619 PolarHBondContact O-N 3.12Å; L615-L645 HydrophobicContact CD2-CD1 4.25Å; L615-L645 HydrophobicContact CD2-CD2 3.95Å; L615-M694 HydrophobicContact CB-CE 4.04Å; L615-M694 HydrophobicContact CD2-CE 4.12Å; L615-M694 HydrophobicContact CG-CE 4.27Å
616A98Very high96.2Very high0 Ų013.9 Ų13.90%08%0.077CC..Hα-helixtrans-61.4-45.317300000111.8S612 R613 T614 H619 V620 K690 I693 M694 I697S612-A616 PolarHBondContact O-N 3.27Å; S612-A616 VanDerWaalsContact O-N 3.13Å; R613-A616 PolarHBondContact O-N 3.46Å; T614-A616 VanDerWaalsContact C-N 3.34Å; T614-A616 PolarHBondContact O-N 2.94Å; A616-H619 WeakPolarHBondContact O-CB 3.3Å; A616-H619 PolarHBondContact O-N 3.01Å; A616-V620 WeakPolarHBondContact O-CG2 3.32Å; A616-V620 PolarHBondContact O-N 3.37Å; A616-V620 VanDerWaalsContact O-N 3.07Å; A616-K690 HydrophobicContact CB-CD 4.41Å; A616-I693 HydrophobicContact CB-CG2 4.06Å; A616-M694 HydrophobicContact CB-CB 4.24Å; A616-M694 HydrophobicContact CB-CE 3.98Å; A616-I697 HydrophobicContact CB-CD1 4.19Å
617G97.5Very high96.3Very high2 Ų213.6 Ų13.62%0.0218%0.075CC..Hα-helixtrans-58-48175.700000113.4R613 T614 H619 V620 R621R613-G617 PolarHBondContact O-N 2.94Å; T614-G617 PolarHBondContact O-N 3.11Å; T614-G617 VanDerWaalsContact O-N 3.17Å; G617-H619 VanDerWaalsContact C-N 3.33Å; G617-H619 PolarHBondContact O-N 3.47Å; G617-V620 PolarHBondContact O-N 2.97Å; G617-R621 WeakPolarHBondContact O-CG 3.5Å; G617-R621 PolarHBondContact O-N 2.99Å; G617-R621 VanDerWaalsContact O-N 3.14Å
618L98.2Very high96.1Very high1 Ų115.2 Ų15.21%0.0059%0.085CC..Hα-helixtrans-62.3-37.4175.1-64.2172.6000112.1F502 Q550 C553 L560 Y564 C567 T614 L615 V620 R621 L622F502-L618 HydrophobicContact CZ-CD1 4.17Å; Q550-L618 HydrophobicContact CB-CD2 4.33Å; Q550-L618 HydrophobicContact CG-CD2 4.06Å; Q550-L618 HydrophobicContact CG-CG 4.35Å; C553-L618 HydrophobicContact CB-CD2 3.95Å; L560-L618 HydrophobicContact CD1-CB 4.41Å; L560-L618 HydrophobicContact CD1-CD2 3.73Å; Y564-L618 HydrophobicContact CD2-CB 3.77Å; Y564-L618 HydrophobicContact CE2-CB 4.44Å; C567-L618 HydrophobicContact CB-CD1 3.89Å; T614-L618 HydrophobicContact CG2-CD1 4.18Å; T614-L618 HydrophobicContact CG2-CG 4.43Å; T614-L618 WeakPolarHBondContact O-CG 3.45Å; T614-L618 PolarHBondContact O-N 2.8Å; L615-L618 PolarHBondContact O-N 2.74Å; L618-V620 PolarHBondContact O-N 3.19Å; L618-R621 WeakPolarHBondContact O-CB 3.4Å; L618-R621 PolarHBondContact O-N 2.92Å; L618-L622 PolarHBondContact O-N 3.42Å
619H97.7Very high95.9Very high2 Ų219.3 Ų19.31%0.00911%0.113CC..Hα-helixtrans-62.8-41.8176.1-16092000112.2Y564 L615 A616 G617 R621 L622 S623 I697 F875Y564-H619 HydrophobicContact CE2-CB 3.78Å; Y564-H619 AromaticContact CE2-ND1 3.81Å; Y564-H619 AromaticContact CZ-ND1 3.74Å; Y564-H619 PolarHBondContact OH-ND1 3.03Å; L615-H619 PolarHBondContact O-N 3.12Å; A616-H619 WeakPolarHBondContact O-CB 3.3Å; A616-H619 PolarHBondContact O-N 3.01Å; G617-H619 VanDerWaalsContact C-N 3.33Å; G617-H619 PolarHBondContact O-N 3.47Å; H619-R621 VanDerWaalsContact C-N 3.29Å; H619-R621 PolarHBondContact O-N 2.89Å; H619-L622 PolarHBondContact O-N 3.39Å; H619-S623 WeakPolarHBondContact O-CB 3.5Å; H619-S623 PolarHBondContact O-N 3.23Å; H619-I697 HydrophobicContact CB-CD1 3.5Å; H619-I697 VanDerWaalsContact CB-CD1 3.5Å; H619-I697 HydrophobicContact CB-CG1 4.35Å; H619-F875 AromaticContact CD2-CZ 3.91Å
620V97.3Very high95.8Very high4 Ų422.2 Ų22.22%0.02412%0.124CC..Hα-helixtrans-63.3-36.9175.6173.10000111A616 G617 L618 S623 R624 I693 V756 P757 V759 F875A616-V620 WeakPolarHBondContact O-CG2 3.32Å; A616-V620 PolarHBondContact O-N 3.37Å; A616-V620 VanDerWaalsContact O-N 3.07Å; G617-V620 PolarHBondContact O-N 2.97Å; L618-V620 PolarHBondContact O-N 3.19Å; V620-S623 PolarHBondContact O-N 3.02Å; V620-R624 WeakPolarHBondContact O-CB 3.42Å; V620-R624 PolarHBondContact O-N 3.44Å; V620-I693 HydrophobicContact CG2-CG2 3.52Å; V620-V756 HydrophobicContact CG1-CG1 4.16Å; V620-P757 WeakPolarHBondContact CG1-O 3.24Å; V620-V759 HydrophobicContact CG2-CG2 3.77Å; V620-F875 HydrophobicContact CG2-CZ 4.32Å
621R96.8Very high95.7Very high28 Ų2822.7 Ų22.711%0.10613%0.127CC..Hα-helixtrans-66.2-44173.3-62-62.4-178-97.7-1.2112.1L547 A554 L560 G617 L618 H619 S623 R624 L625L547-R621 VanDerWaalsContact CD1-NH2 3.32Å; A554-R621 HydrophobicContact CB-CB 3.89Å; A554-R621 HydrophobicContact CB-CG 3.95Å; L560-R621 HydrophobicContact CD1-CB 4.22Å; L560-R621 HydrophobicContact CD2-CB 3.9Å; G617-R621 WeakPolarHBondContact O-CG 3.5Å; G617-R621 PolarHBondContact O-N 2.99Å; G617-R621 VanDerWaalsContact O-N 3.14Å; L618-R621 WeakPolarHBondContact O-CB 3.4Å; L618-R621 PolarHBondContact O-N 2.92Å; H619-R621 VanDerWaalsContact C-N 3.29Å; H619-R621 PolarHBondContact O-N 2.89Å; R621-S623 VanDerWaalsContact C-N 3.32Å; R621-S623 PolarHBondContact O-N 3.13Å; R621-R624 PolarHBondContact O-N 3Å; R621-L625 PolarHBondContact O-N 3.13Å; R621-L625 VanDerWaalsContact O-N 3.15Å
622L96.8Very high95.5Very high0 Ų027.3 Ų27.30%015%0.148CC..Hα-helixtrans-59-43.6174.4-76170.6000111.2L560 L561 Y564 L618 H619 L625 G626 A627 V628 L631L560-L622 HydrophobicContact CB-CD2 4.39Å; L560-L622 HydrophobicContact CD2-CB 4.43Å; L560-L622 HydrophobicContact CD2-CD2 3.66Å; L560-L622 HydrophobicContact CD2-CG 3.84Å; L560-L622 HydrophobicContact CG-CD2 3.66Å; L560-L622 HydrophobicContact CG-CG 3.9Å; L561-L622 HydrophobicContact CD2-CD2 3.62Å; L561-L622 HydrophobicContact CG-CD2 3.92Å; Y564-L622 HydrophobicContact CD1-CD1 4.43Å; Y564-L622 HydrophobicContact CD2-CD1 3.49Å; Y564-L622 VanDerWaalsContact CD2-CD1 3.49Å; Y564-L622 HydrophobicContact CE2-CD1 4.05Å; Y564-L622 HydrophobicContact CG-CD1 3.71Å; L618-L622 PolarHBondContact O-N 3.42Å; H619-L622 PolarHBondContact O-N 3.39Å; L622-L625 PolarHBondContact O-N 3.23Å; L622-G626 PolarHBondContact O-N 3.33Å; L622-A627 HydrophobicContact CD2-CB 3.71Å; L622-A627 PolarHBondContact O-N 2.78Å; L622-V628 HydrophobicContact CB-CG2 3.67Å; L622-L631 HydrophobicContact CD1-CD1 4.19Å; L622-L631 HydrophobicContact CD1-CD2 4.31Å
623S96.5Very high95.4Very high12 Ų1232.2 Ų32.28%0.08417%0.171CC..Hα-helixtrans-61.9-45.6178.6-179.10000111.4H619 V620 R621 L625 G626 G758H619-S623 WeakPolarHBondContact O-CB 3.5Å; H619-S623 PolarHBondContact O-N 3.23Å; V620-S623 PolarHBondContact O-N 3.02Å; R621-S623 VanDerWaalsContact C-N 3.32Å; R621-S623 PolarHBondContact O-N 3.13Å; S623-L625 VanDerWaalsContact C-N 3.25Å; S623-L625 PolarHBondContact O-N 2.99Å; S623-G626 PolarHBondContact O-N 3.14Å; S623-G626 VanDerWaalsContact O-N 3.08Å; S623-G758 WeakPolarHBondContact CB-O 3.34Å; S623-G758 PolarHBondContact OG-O 3.35Å
624R94.1Very high95.2Very high108 Ų10833.4 Ų33.441%0.40818%0.176SC..Hα-helixtrans-60.8-31.2177.3-169.6-174.470.8-175.93.1113.2V620 R621V620-R624 WeakPolarHBondContact O-CB 3.42Å; V620-R624 PolarHBondContact O-N 3.44Å; R621-R624 PolarHBondContact O-N 3Å
625L93.7Very high95Very high73 Ų7333.6 Ų33.638%0.38218%0.178SC..Hα-helixtrans-90-7.7177.1-64.2179.4000113.7L560 R621 L622 S623 A627L560-L625 HydrophobicContact CD2-CD1 3.83Å; R621-L625 PolarHBondContact O-N 3.13Å; R621-L625 VanDerWaalsContact O-N 3.15Å; L622-L625 PolarHBondContact O-N 3.23Å; S623-L625 VanDerWaalsContact C-N 3.25Å; S623-L625 PolarHBondContact O-N 2.99Å; L625-A627 HydrophobicContact CB-CB 4.39Å; L625-A627 PolarHBondContact O-N 2.85Å
626G93.4Very high94.5Very high47 Ų4735.7 Ų35.749%0.48519%0.192SC..THydrogen-bonded Turntrans78-2.2-173.100000115L622 S623 V628 S629L622-G626 PolarHBondContact O-N 3.33Å; S623-G626 PolarHBondContact O-N 3.14Å; S623-G626 VanDerWaalsContact O-N 3.08Å; G626-V628 VanDerWaalsContact C-N 3.26Å; G626-V628 PolarHBondContact O-N 3.39Å; G626-S629 PolarHBondContact O-OG 3.07Å
627A94.7Very high93.7Very high1 Ų144.1 Ų44.11%0.00823%0.229CC..G310 helixtrans-72.7-8.9-173.600000114.8E557 L622 L625 S629 R630E557-A627 HydrophobicContact CG-CB 3.74Å; L622-A627 HydrophobicContact CD2-CB 3.71Å; L622-A627 PolarHBondContact O-N 2.78Å; L625-A627 HydrophobicContact CB-CB 4.39Å; L625-A627 PolarHBondContact O-N 2.85Å; A627-S629 PolarHBondContact O-N 3.01Å; A627-S629 VanDerWaalsContact O-N 3.14Å; A627-R630 PolarHBondContact O-N 2.94Å
628V92.4Very high92.9Very high35 Ų3552.3 Ų52.321%0.21227%0.267CS..G310 helixtrans-56.1-30.3174179.40000111.8L622 G626 R630 L631 A874L622-V628 HydrophobicContact CB-CG2 3.67Å; G626-V628 VanDerWaalsContact C-N 3.26Å; G626-V628 PolarHBondContact O-N 3.39Å; V628-R630 VanDerWaalsContact C-N 3.26Å; V628-R630 PolarHBondContact O-N 3.34Å; V628-L631 VanDerWaalsContact O-CB 3.24Å; V628-L631 WeakPolarHBondContact O-CB 3.49Å; V628-L631 PolarHBondContact O-N 3.38Å; V628-L631 VanDerWaalsContact O-N 3.15Å; V628-A874 HydrophobicContact CB-CB 4.28Å; V628-A874 HydrophobicContact CG1-CB 4.15Å; V628-A874 HydrophobicContact CG2-CB 4.02Å
629S90.6Very high92.2Very high87 Ų8756.8 Ų56.861%0.60829%0.291SS*.G310 helixtrans-55.8-38.7174.554.90000113.1G626 A627 H632G626-S629 PolarHBondContact O-OG 3.07Å; A627-S629 PolarHBondContact O-N 3.01Å; A627-S629 VanDerWaalsContact O-N 3.14Å; S629-H632 PolarHBondContact O-CE1 3.13Å; S629-H632 VanDerWaalsContact O-CE1 3.31Å; S629-H632 PolarHBondContact O-ND1 2.89Å
630R94.2Very high91.6Very high63 Ų6357.7 Ų57.724%0.23830%0.295CS..G310 helixtrans-84.1-9.5179.3-65.8-174.458.8-144.2-9.9114.3E557 E558 L561 A627 V628 H632 E633E557-R630 WeakPolarHBondContact OE1-CD 3.38Å; E557-R630 IonicContact OE1-CZ 2.71Å; E557-R630 IonicContact OE1-NE 2.71Å; E557-R630 IonicContact OE1-NH1 2.69Å; E557-R630 PolarHBondContact OE1-NH1 3.34Å; E558-R630 IonicContact OE2-CZ 2.85Å; E558-R630 IonicContact OE2-NH1 3.47Å; E558-R630 PolarHBondContact OE2-NH1 2.9Å; E558-R630 IonicContact OE2-NH2 3.91Å; E558-R630 PolarHBondContact OE2-NH2 3.18Å; L561-R630 HydrophobicContact CD1-CB 4.11Å; L561-R630 HydrophobicContact CD2-CB 4.4Å; A627-R630 PolarHBondContact O-N 2.94Å; V628-R630 VanDerWaalsContact C-N 3.26Å; V628-R630 PolarHBondContact O-N 3.34Å; R630-H632 PolarHBondContact O-N 2.97Å; R630-E633 WeakPolarHBondContact CG-OE1 3.2Å; R630-E633 IonicContact CZ-OE2 2.77Å; R630-E633 IonicContact NE-OE1 3.22Å; R630-E633 IonicContact NE-OE2 2.7Å; R630-E633 PolarHBondContact NE-OE2 2.84Å; R630-E633 IonicContact NH2-OE2 3.38Å; R630-E633 PolarHBondContact NH2-OE2 3.07Å; R630-E633 WeakPolarHBondContact O-CB 3.36Å; R630-E633 WeakPolarHBondContact O-CG 3.48Å; R630-E633 PolarHBondContact O-N 3.39Å
631L92.6Very high91.2Very high11 Ų1161.5 Ų61.56%0.05831%0.312CS..G310 helixtrans-57.1-30.7-172.1-178.854.5000113.7L561 Y564 L622 V628 E633 F634 V635 F640L561-L631 HydrophobicContact CD2-CD1 4.45Å; Y564-L631 HydrophobicContact CD1-CD1 3.4Å; Y564-L631 HydrophobicContact CD1-CD2 4.35Å; Y564-L631 HydrophobicContact CD1-CG 4.48Å; Y564-L631 HydrophobicContact CE1-CD1 3.72Å; Y564-L631 HydrophobicContact CE1-CD2 3.87Å; Y564-L631 HydrophobicContact CE1-CG 4.36Å; Y564-L631 HydrophobicContact CG-CD1 4.08Å; L622-L631 HydrophobicContact CD1-CD1 4.19Å; L622-L631 HydrophobicContact CD1-CD2 4.31Å; V628-L631 VanDerWaalsContact O-CB 3.24Å; V628-L631 WeakPolarHBondContact O-CB 3.49Å; V628-L631 PolarHBondContact O-N 3.38Å; V628-L631 VanDerWaalsContact O-N 3.15Å; L631-E633 PolarHBondContact O-N 3.44Å; L631-F634 PolarHBondContact O-N 3.3Å; L631-V635 HydrophobicContact CD1-CG2 4.48Å; L631-V635 PolarHBondContact O-N 2.81Å; L631-F640 HydrophobicContact CD2-CE2 3.88Å
632H91.7Very high90.8Very high96 Ų9661.4 Ų61.444%0.44432%0.315SS..G310 helixtrans-64.4-20.4176.575.4-79000114.3S629 R630 F634 V635 F637S629-H632 PolarHBondContact O-CE1 3.13Å; S629-H632 VanDerWaalsContact O-CE1 3.31Å; S629-H632 PolarHBondContact O-ND1 2.89Å; R630-H632 PolarHBondContact O-N 2.97Å; H632-F634 PolarHBondContact O-N 2.91Å; H632-V635 WeakPolarHBondContact CA-O 3.43Å; H632-F637 HydrophobicContact CB-CD2 4.48Å; H632-F637 HydrophobicContact CB-CE1 4.44Å; H632-F637 HydrophobicContact CB-CE2 3.78Å; H632-F637 HydrophobicContact CB-CZ 3.76Å
633E93.5Very high90.5Very high103 Ų10364.9 Ų64.948%0.48133%0.331SS..G310 helixtrans-68.7-25.1172-59.9161.6-159.500111.3R630 L631R630-E633 WeakPolarHBondContact CG-OE1 3.2Å; R630-E633 IonicContact CZ-OE2 2.77Å; R630-E633 IonicContact NE-OE1 3.22Å; R630-E633 IonicContact NE-OE2 2.7Å; R630-E633 PolarHBondContact NE-OE2 2.84Å; R630-E633 IonicContact NH2-OE2 3.38Å; R630-E633 PolarHBondContact NH2-OE2 3.07Å; R630-E633 WeakPolarHBondContact O-CB 3.36Å; R630-E633 WeakPolarHBondContact O-CG 3.48Å; R630-E633 PolarHBondContact O-N 3.39Å; L631-E633 PolarHBondContact O-N 3.44Å
634F94.5Very high90.1Very high26 Ų2664.8 Ų64.811%0.11433%0.33CS..THydrogen-bonded Turntrans-107.2-40.4-171.5-67.4-96.1000112.8E558 L561 V562 K565 L631 H632E558-F634 VanDerWaalsContact OE1-CZ 3.29Å; E558-F634 WeakPolarHBondContact OE1-CZ 3.36Å; L561-F634 HydrophobicContact CB-CD1 3.97Å; L561-F634 HydrophobicContact CB-CD2 3.79Å; L561-F634 HydrophobicContact CB-CE1 3.88Å; L561-F634 HydrophobicContact CB-CE2 3.73Å; L561-F634 HydrophobicContact CB-CG 3.95Å; L561-F634 HydrophobicContact CB-CZ 3.76Å; L561-F634 HydrophobicContact CD1-CD2 4.26Å; L561-F634 HydrophobicContact CD1-CE2 3.68Å; L561-F634 HydrophobicContact CD1-CZ 4.1Å; L561-F634 HydrophobicContact CD2-CD2 3.98Å; L561-F634 HydrophobicContact CD2-CE2 4.25Å; L561-F634 HydrophobicContact CG-CD2 4.23Å; L561-F634 HydrophobicContact CG-CE2 4.09Å; L561-F634 HydrophobicContact CG-CZ 4.49Å; V562-F634 HydrophobicContact CG2-CD1 4.21Å; V562-F634 HydrophobicContact CG2-CE1 3.8Å; K565-F634 HydrophobicContact CB-CB 4.25Å; K565-F634 HydrophobicContact CD-CB 4.14Å; K565-F634 HydrophobicContact CD-CD1 4.39Å; K565-F634 WeakPolarHBondContact CD-O 3.45Å; K565-F634 WeakPolarHBondContact CE-O 3.41Å; K565-F634 PolarHBondContact NZ-O 3.49Å; L631-F634 PolarHBondContact O-N 3.3Å; H632-F634 PolarHBondContact O-N 2.91Å
635V92.1Very high90.1Very high7 Ų759.7 Ų59.74%0.04231%0.311CS..SBendtrans-127.3117.8176.7-176.80000107.7K565 H568 L631 H632 D639 F640K565-V635 HydrophobicContact CB-CG2 4.16Å; K565-V635 HydrophobicContact CG-CG2 4.18Å; H568-V635 HydrophobicContact CB-CG2 4.37Å; L631-V635 HydrophobicContact CD1-CG2 4.48Å; L631-V635 PolarHBondContact O-N 2.81Å; H632-V635 WeakPolarHBondContact CA-O 3.43Å; V635-D639 HydrophobicContact CG1-CB 4.24Å; V635-F640 HydrophobicContact CB-CD2 4.32Å; V635-F640 HydrophobicContact CG1-CB 4.21Å; V635-F640 HydrophobicContact CG1-CD2 3.82Å; V635-F640 HydrophobicContact CG1-CG 4.47Å
636S88.3Confident90.1Very high43 Ų4356.3 Ų56.330%0.30129%0.293SS..  trans-67.1157.1-178.283.40000111.6E638 D639 F640S636-E638 PolarHBondContact O-N 2.83Å; S636-E638 PolarHBondContact OG-N 3.18Å; S636-D639 WeakPolarHBondContact CB-OD2 3.39Å; S636-D639 PolarHBondContact O-N 3.35Å; S636-D639 WeakPolarHBondContact OG-CB 3.46Å; S636-D639 PolarHBondContact OG-N 3.3Å; S636-D639 VanDerWaalsContact OG-N 3.08Å; S636-D639 PolarHBondContact OG-OD2 3.16Å; S636-F640 WeakPolarHBondContact O-CB 3.31Å; S636-F640 PolarHBondContact O-N 3.47Å
637F82.2Confident90Very high178 Ų17854.1 Ų54.178%0.78127%0.27SS*.Hα-helixtrans-59.8-30176.4-68.4-71.2000113.1H632H632-F637 HydrophobicContact CB-CD2 4.48Å; H632-F637 HydrophobicContact CB-CE1 4.44Å; H632-F637 HydrophobicContact CB-CE2 3.78Å; H632-F637 HydrophobicContact CB-CZ 3.76Å
638E79.8Confident90Very high173 Ų17355.2 Ų55.281%0.80827%0.274SS*.Hα-helixtrans-75.7-39.9177.7-62.9-179.5-178.100111.6S636 F640 Q641S636-E638 PolarHBondContact O-N 2.83Å; S636-E638 PolarHBondContact OG-N 3.18Å; E638-F640 VanDerWaalsContact C-N 3.34Å; E638-Q641 WeakPolarHBondContact O-CG 3.15Å
639D83.4Confident90.2Very high96 Ų9653.6 Ų53.651%0.51327%0.265SS..Hα-helixtrans-72.7-26.6177.6-64.6-52.3000112.8H568 V635 S636 Q641H568-D639 PolarHBondContact CE1-O 3.29Å; V635-D639 HydrophobicContact CG1-CB 4.24Å; S636-D639 WeakPolarHBondContact CB-OD2 3.39Å; S636-D639 PolarHBondContact O-N 3.35Å; S636-D639 WeakPolarHBondContact OG-CB 3.46Å; S636-D639 PolarHBondContact OG-N 3.3Å; S636-D639 VanDerWaalsContact OG-N 3.08Å; S636-D639 PolarHBondContact OG-OD2 3.16Å; D639-Q641 VanDerWaalsContact C-N 3.31Å; D639-Q641 PolarHBondContact O-N 3.21Å
640F85.1Confident90.5Very high20 Ų2049.5 Ų49.59%0.08824%0.236CC..Hα-helixtrans-61.1-38.1-169.5-162.9-86.4000113.3Y564 H568 L631 V635 S636 E638 V642 L645 L701Y564-F640 AromaticContact CE1-CE2 3.99Å; Y564-F640 HydrophobicContact CE1-CE2 3.99Å; H568-F640 PolarHBondContact NE2-O 2.94Å; H568-F640 VanDerWaalsContact NE2-O 3.07Å; L631-F640 HydrophobicContact CD2-CE2 3.88Å; V635-F640 HydrophobicContact CB-CD2 4.32Å; V635-F640 HydrophobicContact CG1-CB 4.21Å; V635-F640 HydrophobicContact CG1-CD2 3.82Å; V635-F640 HydrophobicContact CG1-CG 4.47Å; S636-F640 WeakPolarHBondContact O-CB 3.31Å; S636-F640 PolarHBondContact O-N 3.47Å; E638-F640 VanDerWaalsContact C-N 3.34Å; F640-V642 HydrophobicContact CD1-CB 4.46Å; F640-V642 HydrophobicContact CD1-CG2 3.59Å; F640-V642 HydrophobicContact CE1-CG2 3.9Å; F640-V642 PolarHBondContact O-N 2.81Å; F640-L645 HydrophobicContact CD1-CD1 4.02Å; F640-L645 HydrophobicContact CE1-CD1 3.54Å; F640-L645 HydrophobicContact CZ-CD1 3.98Å; F640-L701 HydrophobicContact CD1-CD1 4.34Å; F640-L701 HydrophobicContact CE1-CD1 3.51Å; F640-L701 HydrophobicContact CZ-CD1 3.88Å
641Q87.8Confident90.6Very high84 Ų8447.3 Ų47.339%0.39323%0.227SC..  trans43.459.4173.7-61.5-170.518.300114.8M572 E638 D639 E643 V644 L645M572-Q641 HydrophobicContact CE-CB 3.7Å; M572-Q641 HydrophobicContact CE-CG 4.07Å; M572-Q641 VanDerWaalsContact CE-OE1 3.23Å; M572-Q641 HydrophobicContact SD-CB 4.42Å; E638-Q641 WeakPolarHBondContact O-CG 3.15Å; D639-Q641 VanDerWaalsContact C-N 3.31Å; D639-Q641 PolarHBondContact O-N 3.21Å; Q641-E643 PolarHBondContact O-N 3.15Å; Q641-E643 VanDerWaalsContact O-N 3.08Å; Q641-V644 HydrophobicContact CB-CB 4.31Å; Q641-V644 HydrophobicContact CB-CG2 4.13Å; Q641-V644 WeakPolarHBondContact O-CB 3.49Å; Q641-V644 PolarHBondContact O-N 3.5Å; Q641-L645 PolarHBondContact O-N 3.02Å
642V90.4Very high90.8Very high27 Ų2746.8 Ų46.816%0.16423%0.225CC..Hα-helixtrans-48.4-42.3-176.8-1660000113F640 V644 L645 V646 L701 M702F640-V642 HydrophobicContact CD1-CB 4.46Å; F640-V642 HydrophobicContact CD1-CG2 3.59Å; F640-V642 HydrophobicContact CE1-CG2 3.9Å; F640-V642 PolarHBondContact O-N 2.81Å; V642-V644 PolarHBondContact O-N 2.89Å; V642-V644 VanDerWaalsContact O-N 3.16Å; V642-L645 PolarHBondContact O-N 3.05Å; V642-V646 HydrophobicContact CG1-CG1 4.48Å; V642-V646 PolarHBondContact O-N 2.97Å; V642-L701 HydrophobicContact CG1-CB 4.12Å; V642-L701 HydrophobicContact CG2-CB 3.76Å; V642-L701 HydrophobicContact CG2-CD1 4.16Å; V642-M702 HydrophobicContact CB-CG 3.9Å; V642-M702 HydrophobicContact CB-SD 4.38Å; V642-M702 HydrophobicContact CG1-CG 3.68Å; V642-M702 HydrophobicContact CG1-SD 4.03Å
643E88.9Confident91.1Very high72 Ų7242.5 Ų42.534%0.33621%0.205SC..Hα-helixtrans-56.3-29.4178.5-72.3177.8-172.400113.3Q641 V646 E647 M702Q641-E643 PolarHBondContact O-N 3.15Å; Q641-E643 VanDerWaalsContact O-N 3.08Å; E643-V646 WeakPolarHBondContact O-CG2 3.49Å; E643-E647 VanDerWaalsContact O-CG 3.25Å; E643-E647 WeakPolarHBondContact O-CG 3.19Å; E643-M702 HydrophobicContact CG-CE 3.57Å; E643-M702 HydrophobicContact CG-SD 4.06Å
644V89.1Confident91.3Very high10 Ų1037.6 Ų37.66%0.06118%0.182CC..Hα-helixtrans-82.6-33.8177179.70000111.5M572 Q641 V642 E647M572-V644 HydrophobicContact CE-CB 4.17Å; M572-V644 HydrophobicContact CE-CG1 4.02Å; M572-V644 HydrophobicContact CE-CG2 4.42Å; M572-V644 HydrophobicContact SD-CB 4.37Å; M572-V644 HydrophobicContact SD-CG1 4.12Å; Q641-V644 HydrophobicContact CB-CB 4.31Å; Q641-V644 HydrophobicContact CB-CG2 4.13Å; Q641-V644 WeakPolarHBondContact O-CB 3.49Å; Q641-V644 PolarHBondContact O-N 3.5Å; V642-V644 PolarHBondContact O-N 2.89Å; V642-V644 VanDerWaalsContact O-N 3.16Å; V644-E647 PolarHBondContact O-N 3.26Å
645L92.6Very high91.5Very high2 Ų236.3 Ų36.31%0.0118%0.177CC..Hα-helixtrans-67.9-35.5-179.5-55.9-178.1000112.6V571 M572 L615 F640 Q641 V642 M694V571-L645 HydrophobicContact CG1-CD2 3.73Å; M572-L645 HydrophobicContact SD-CD2 3.88Å; L615-L645 HydrophobicContact CD2-CD1 4.25Å; L615-L645 HydrophobicContact CD2-CD2 3.95Å; F640-L645 HydrophobicContact CD1-CD1 4.02Å; F640-L645 HydrophobicContact CE1-CD1 3.54Å; F640-L645 HydrophobicContact CZ-CD1 3.98Å; Q641-L645 PolarHBondContact O-N 3.02Å; V642-L645 PolarHBondContact O-N 3.05Å; L645-M694 HydrophobicContact CB-SD 4.17Å
646V94.1Very high91.7Very high1 Ų136.3 Ų36.31%0.00618%0.177CC..THydrogen-bonded Turntrans-77.4-18.4-179.3-62.70000114.1V642 E643 L650 L695 M702 F707 L710V642-V646 HydrophobicContact CG1-CG1 4.48Å; V642-V646 PolarHBondContact O-N 2.97Å; E643-V646 WeakPolarHBondContact O-CG2 3.49Å; V646-L650 VanDerWaalsContact O-CB 3.22Å; V646-L650 WeakPolarHBondContact O-CB 3.49Å; V646-L650 PolarHBondContact O-N 3.37Å; V646-L695 HydrophobicContact CB-CD2 3.93Å; V646-L695 HydrophobicContact CG1-CD2 4.3Å; V646-M702 HydrophobicContact CG2-SD 4.39Å; V646-F707 HydrophobicContact CG1-CE2 4.46Å; V646-L710 HydrophobicContact CG2-CD2 3.61Å
647E91.9Very high92.1Very high2 Ų234.3 Ų34.31%0.00916%0.163CC..Hα-helixtrans-62.3-51.7-170.9-83.5-82168.200113.4F578 E643 V644 L650 R651 R714F578-E647 HydrophobicContact CD1-CG 4.47Å; F578-E647 HydrophobicContact CE1-CB 4.48Å; F578-E647 HydrophobicContact CE1-CG 3.64Å; F578-E647 VanDerWaalsContact CZ-CD 3.5Å; F578-E647 HydrophobicContact CZ-CG 3.9Å; E643-E647 VanDerWaalsContact O-CG 3.25Å; E643-E647 WeakPolarHBondContact O-CG 3.19Å; V644-E647 PolarHBondContact O-N 3.26Å; E647-L650 PolarHBondContact O-N 3.44Å; E647-R651 WeakPolarHBondContact O-CD 3.29Å; E647-R651 WeakPolarHBondContact O-CG 3.19Å; E647-R651 PolarHBondContact O-N 3.01Å; E647-R651 IonicContact OE2-CZ 3.41Å; E647-R651 VanDerWaalsContact OE2-CZ 3.27Å; E647-R651 IonicContact OE2-NE 2.75Å; E647-R651 PolarHBondContact OE2-NE 3.44Å; E647-R651 IonicContact OE2-NH2 3.69Å; E647-R651 PolarHBondContact OE2-NH2 3.45Å; E647-R714 IonicContact OE1-CZ 2.69Å; E647-R714 VanDerWaalsContact OE1-CZ 3.31Å; E647-R714 IonicContact OE1-NE 3.21Å; E647-R714 PolarHBondContact OE1-NE 3.45Å; E647-R714 VanDerWaalsContact OE1-NE 3.11Å; E647-R714 IonicContact OE1-NH2 2.64Å; E647-R714 PolarHBondContact OE1-NH2 3.42Å; E647-R714 IonicContact OE2-CZ 2.76Å; E647-R714 IonicContact OE2-NE 2.84Å; E647-R714 PolarHBondContact OE2-NE 3.12Å; E647-R714 IonicContact OE2-NH2 3.4Å
648Y93.9Very high92.8Very high24 Ų2425.9 Ų25.99%0.09413%0.126CC..Hα-helixtrans-60.2-52.7-178.1-81.9-70.9000112.1L609 L650 R651 C652L609-Y648 WeakPolarHBondContact CD1-O 3.45Å; L609-Y648 HydrophobicContact CD2-CD1 3.69Å; L609-Y648 HydrophobicContact CD2-CG 4.14Å; Y648-L650 PolarHBondContact O-N 3.32Å; Y648-R651 PolarHBondContact O-N 3.5Å; Y648-C652 PolarHBondContact O-N 2.89Å; Y648-C652 VanDerWaalsContact O-N 3.11Å
649P97.1Very high93.6Very high1 Ų119 Ų191%0.00610%0.096CC..Hα-helixtrans-54.8-45.5172.3-31.939.2000114.5R651 C652 L653 D691 M694 L695P649-R651 VanDerWaalsContact C-N 3.33Å; P649-R651 PolarHBondContact O-N 3.33Å; P649-C652 WeakPolarHBondContact O-CB 3.27Å; P649-C652 PolarHBondContact O-N 3.22Å; P649-L653 WeakPolarHBondContact O-CG 3.32Å; P649-L653 PolarHBondContact O-N 2.97Å; P649-D691 HydrophobicContact CB-CB 3.83Å; P649-M694 HydrophobicContact CB-CB 4.32Å; P649-M694 HydrophobicContact CG-CB 3.79Å; P649-M694 HydrophobicContact CG-CG 3.83Å; P649-L695 HydrophobicContact CB-CD2 4.43Å
650L97.4Very high94.1Very high1 Ų116.6 Ų16.61%0.0058%0.084CC..Hα-helixtrans-62.9-40.2-179-176.953000111.7V646 E647 Y648 L653 V654 L695 L710 V711 R714 Y715V646-L650 VanDerWaalsContact O-CB 3.22Å; V646-L650 WeakPolarHBondContact O-CB 3.49Å; V646-L650 PolarHBondContact O-N 3.37Å; E647-L650 PolarHBondContact O-N 3.44Å; Y648-L650 PolarHBondContact O-N 3.32Å; L650-L653 PolarHBondContact O-N 3.16Å; L650-V654 HydrophobicContact CD1-CG2 4.32Å; L650-V654 WeakPolarHBondContact O-CB 3.49Å; L650-V654 VanDerWaalsContact O-CG2 3.25Å; L650-V654 WeakPolarHBondContact O-CG2 3.39Å; L650-V654 PolarHBondContact O-N 2.87Å; L650-L695 HydrophobicContact CB-CD2 4.08Å; L650-L695 HydrophobicContact CD1-CD1 4.24Å; L650-L710 HydrophobicContact CD2-CD2 4.34Å; L650-L710 HydrophobicContact CD2-CG 3.93Å; L650-V711 HydrophobicContact CD1-CG2 4.22Å; L650-V711 HydrophobicContact CD2-CG2 4.33Å; L650-R714 HydrophobicContact CD2-CB 3.89Å; L650-R714 HydrophobicContact CD2-CG 3.73Å; L650-R714 HydrophobicContact CG-CB 3.93Å; L650-R714 HydrophobicContact CG-CG 4.13Å; L650-Y715 HydrophobicContact CD1-CE2 4.15Å
651R96Very high94.6Very high16 Ų1615.9 Ų15.96%0.068%0.082CC..Hα-helixtrans-65-40175.7-65.6163.9-168.7-168.59.7112.3F578 Y598 V600 V605 E647 Y648 P649 V654 L655F578-R651 VanDerWaalsContact CZ-NH2 3.34Å; Y598-R651 HydrophobicContact CD1-CG 4.06Å; Y598-R651 HydrophobicContact CE1-CB 4.34Å; Y598-R651 VanDerWaalsContact CE1-CD 3.42Å; Y598-R651 HydrophobicContact CE1-CG 3.5Å; Y598-R651 VanDerWaalsContact CE1-CG 3.5Å; V600-R651 HydrophobicContact CG2-CB 4.05Å; V600-R651 HydrophobicContact CG2-CG 4.15Å; V605-R651 HydrophobicContact CG2-CB 4.12Å; E647-R651 WeakPolarHBondContact O-CD 3.29Å; E647-R651 WeakPolarHBondContact O-CG 3.19Å; E647-R651 PolarHBondContact O-N 3.01Å; E647-R651 IonicContact OE2-CZ 3.41Å; E647-R651 VanDerWaalsContact OE2-CZ 3.27Å; E647-R651 IonicContact OE2-NE 2.75Å; E647-R651 PolarHBondContact OE2-NE 3.44Å; E647-R651 IonicContact OE2-NH2 3.69Å; E647-R651 PolarHBondContact OE2-NH2 3.45Å; Y648-R651 PolarHBondContact O-N 3.5Å; P649-R651 VanDerWaalsContact C-N 3.33Å; P649-R651 PolarHBondContact O-N 3.33Å; R651-V654 PolarHBondContact O-N 2.97Å; R651-L655 WeakPolarHBondContact O-CB 3.4Å; R651-L655 PolarHBondContact O-N 2.99Å
652C97Very high94.9Very high0 Ų015.1 Ų15.10%08%0.078CC..Hα-helixtrans-62.7-45.5176.3-172.60000111.3L609 Y648 P649 L655 V656 Y678L609-C652 HydrophobicContact CD1-CB 3.83Å; Y648-C652 PolarHBondContact O-N 2.89Å; Y648-C652 VanDerWaalsContact O-N 3.11Å; P649-C652 WeakPolarHBondContact O-CB 3.27Å; P649-C652 PolarHBondContact O-N 3.22Å; C652-L655 WeakPolarHBondContact O-CB 3.29Å; C652-L655 PolarHBondContact O-N 3.43Å; C652-V656 WeakPolarHBondContact O-CG2 3.36Å; C652-V656 PolarHBondContact O-N 3.49Å; C652-V656 VanDerWaalsContact O-N 3.14Å; C652-Y678 VanDerWaalsContact SG-CZ 3.53Å
653L97.9Very high95.1Very high6 Ų614.8 Ų14.83%0.0318%0.075CC..Hα-helixtrans-65.2-39.6176.5-69165.7000112.4P649 L650 V656 A657 Y688 D691 I692 L695 V746P649-L653 WeakPolarHBondContact O-CG 3.32Å; P649-L653 PolarHBondContact O-N 2.97Å; L650-L653 PolarHBondContact O-N 3.16Å; L653-V656 PolarHBondContact O-N 3.03Å; L653-A657 PolarHBondContact O-N 3.33Å; L653-Y688 HydrophobicContact CD2-CD2 3.9Å; L653-Y688 HydrophobicContact CD2-CE2 3.55Å; L653-D691 HydrophobicContact CD1-CB 4.35Å; L653-D691 HydrophobicContact CG-CB 4.47Å; L653-I692 HydrophobicContact CD1-CD1 3.97Å; L653-I692 HydrophobicContact CD2-CD1 4.09Å; L653-L695 HydrophobicContact CD1-CD1 3.47Å; L653-L695 VanDerWaalsContact CD1-CD1 3.47Å; L653-L695 HydrophobicContact CD1-CG 4.21Å; L653-V746 HydrophobicContact CD1-CG1 4.45Å
654V98.1Very high95.3Very high0 Ų011.8 Ų11.80%06%0.061CC..Hα-helixtrans-65.8-39173.2170.80000111.8V600 L650 R651 V656 A657 Q658 R714 Y715V600-V654 HydrophobicContact CB-CB 4.43Å; V600-V654 HydrophobicContact CB-CG1 3.67Å; V600-V654 HydrophobicContact CG1-CG1 3.98Å; V600-V654 HydrophobicContact CG2-CB 3.97Å; V600-V654 HydrophobicContact CG2-CG1 3.66Å; L650-V654 HydrophobicContact CD1-CG2 4.32Å; L650-V654 WeakPolarHBondContact O-CB 3.49Å; L650-V654 VanDerWaalsContact O-CG2 3.25Å; L650-V654 WeakPolarHBondContact O-CG2 3.39Å; L650-V654 PolarHBondContact O-N 2.87Å; R651-V654 PolarHBondContact O-N 2.97Å; V654-V656 VanDerWaalsContact C-N 3.33Å; V654-V656 PolarHBondContact O-N 3.08Å; V654-A657 WeakPolarHBondContact O-CB 3.37Å; V654-A657 PolarHBondContact O-N 3.43Å; V654-Q658 HydrophobicContact CG1-CG 4.12Å; V654-Q658 WeakPolarHBondContact O-CB 3.48Å; V654-Q658 WeakPolarHBondContact O-CG 3.39Å; V654-Q658 PolarHBondContact O-N 2.98Å; V654-R714 WeakPolarHBondContact CG1-O 3.5Å; V654-R714 HydrophobicContact CG2-CB 4.25Å; V654-Y715 HydrophobicContact CG2-CD1 4.25Å; V654-Y715 HydrophobicContact CG2-CD2 3.43Å; V654-Y715 VanDerWaalsContact CG2-CD2 3.43Å; V654-Y715 HydrophobicContact CG2-CE1 4.3Å; V654-Y715 HydrophobicContact CG2-CE2 3.48Å; V654-Y715 VanDerWaalsContact CG2-CE2 3.48Å; V654-Y715 HydrophobicContact CG2-CG 3.84Å
655L97.7Very high95.3Very high0 Ų019 Ų190%09%0.087CC..Hα-helixtrans-57.4-47.9175.2166.765000110.4I518 V600 V605 I607 R651 C652 A657 Q658 V659 W664I518-L655 HydrophobicContact CD1-CD1 4.21Å; I518-L655 HydrophobicContact CD1-CD2 4.07Å; V600-L655 HydrophobicContact CG1-CB 3.99Å; V605-L655 HydrophobicContact CG1-CB 4.48Å; V605-L655 HydrophobicContact CG1-CD1 4.07Å; V605-L655 HydrophobicContact CG1-CD2 3.98Å; V605-L655 HydrophobicContact CG1-CG 4.4Å; V605-L655 HydrophobicContact CG2-CB 4.18Å; V605-L655 HydrophobicContact CG2-CD2 4.12Å; I607-L655 HydrophobicContact CG2-CD2 3.86Å; R651-L655 WeakPolarHBondContact O-CB 3.4Å; R651-L655 PolarHBondContact O-N 2.99Å; C652-L655 WeakPolarHBondContact O-CB 3.29Å; C652-L655 PolarHBondContact O-N 3.43Å; L655-A657 VanDerWaalsContact C-N 3.35Å; L655-A657 PolarHBondContact O-N 2.96Å; L655-Q658 PolarHBondContact O-N 3.38Å; L655-V659 HydrophobicContact CD1-CG2 4.02Å; L655-V659 HydrophobicContact CG-CG2 4.46Å; L655-V659 WeakPolarHBondContact O-CG2 3.43Å; L655-V659 PolarHBondContact O-N 3.48Å; L655-W664 HydrophobicContact CD1-CD2 3.91Å; L655-W664 HydrophobicContact CD1-CE3 4.17Å; L655-W664 HydrophobicContact CD1-CH2 3.83Å; L655-W664 HydrophobicContact CD1-CZ2 3.53Å; L655-W664 HydrophobicContact CD1-CZ3 4.13Å
656V96.8Very high95.1Very high7 Ų724.4 Ų24.44%0.04211%0.107CC..Hα-helixtrans-59.8-45.4176.2175.60000111C652 L653 V654 Q658 V659 V660 V675 Y678C652-V656 WeakPolarHBondContact O-CG2 3.36Å; C652-V656 PolarHBondContact O-N 3.49Å; C652-V656 VanDerWaalsContact O-N 3.14Å; L653-V656 PolarHBondContact O-N 3.03Å; V654-V656 VanDerWaalsContact C-N 3.33Å; V654-V656 PolarHBondContact O-N 3.08Å; V656-Q658 VanDerWaalsContact C-N 3.33Å; V656-Q658 PolarHBondContact O-N 2.96Å; V656-V659 PolarHBondContact O-N 2.81Å; V656-V660 WeakPolarHBondContact O-CB 3.36Å; V656-V660 WeakPolarHBondContact O-CG2 3.3Å; V656-V660 PolarHBondContact O-N 3.2Å; V656-V675 HydrophobicContact CG1-CG1 4.05Å; V656-V675 HydrophobicContact CG2-CG1 4.06Å; V656-V675 HydrophobicContact CG2-CG2 4.27Å; V656-Y678 HydrophobicContact CG2-CD1 3.73Å; V656-Y678 HydrophobicContact CG2-CE1 3.72Å
657A97.3Very high95Very high1 Ų125.1 Ų25.11%0.00811%0.111CC..Hα-helixtrans-60.1-39.1175.600000113L653 V654 L655 V660 A661 Y715 L739 E742L653-A657 PolarHBondContact O-N 3.33Å; V654-A657 WeakPolarHBondContact O-CB 3.37Å; V654-A657 PolarHBondContact O-N 3.43Å; L655-A657 VanDerWaalsContact C-N 3.35Å; L655-A657 PolarHBondContact O-N 2.96Å; A657-V660 PolarHBondContact O-N 3.41Å; A657-A661 WeakPolarHBondContact O-CB 3.47Å; A657-A661 PolarHBondContact O-N 3.16Å; A657-Y715 HydrophobicContact CB-CD1 4.45Å; A657-Y715 HydrophobicContact CB-CE1 3.68Å; A657-L739 HydrophobicContact CB-CD2 4.1Å; A657-E742 HydrophobicContact CB-CB 3.5Å; A657-E742 HydrophobicContact CB-CG 3.88Å
658Q97.1Very high94.8Very high0 Ų025.3 Ų25.30%011%0.114CC..Hα-helixtrans-73.8-33.2177.5-69.9-171.81.700113S601 V654 L655 V656 A661 E662 M663 W664 E716 L739S601-Q658 VanDerWaalsContact CA-OE1 3.32Å; V654-Q658 HydrophobicContact CG1-CG 4.12Å; V654-Q658 WeakPolarHBondContact O-CB 3.48Å; V654-Q658 WeakPolarHBondContact O-CG 3.39Å; V654-Q658 PolarHBondContact O-N 2.98Å; L655-Q658 PolarHBondContact O-N 3.38Å; V656-Q658 VanDerWaalsContact C-N 3.33Å; V656-Q658 PolarHBondContact O-N 2.96Å; Q658-A661 CarbonylContact O-C 3.48Å; Q658-A661 PolarHBondContact O-N 3Å; Q658-E662 PolarHBondContact O-N 2.72Å; Q658-M663 HydrophobicContact CB-CB 4.36Å; Q658-M663 HydrophobicContact CB-SD 3.82Å; Q658-M663 HydrophobicContact CG-CE 4.15Å; Q658-M663 HydrophobicContact CG-SD 3.66Å; Q658-M663 WeakPolarHBondContact O-CB 3.26Å; Q658-M663 PolarHBondContact O-N 3.3Å; Q658-W664 VanDerWaalsContact CB-NE1 3.32Å; Q658-E716 PolarHBondContact NE2-OE1 3.48Å; Q658-E716 VanDerWaalsContact NE2-OE1 3.15Å; Q658-L739 HydrophobicContact CG-CD2 3.84Å
659V96.1Very high94.5Very high30 Ų3029.8 Ų29.818%0.18214%0.138CC..Hα-helixtrans-63.5-45.3171.4170.70000109.5L655 V656 E662 W664 L671 V675L655-V659 HydrophobicContact CD1-CG2 4.02Å; L655-V659 HydrophobicContact CG-CG2 4.46Å; L655-V659 WeakPolarHBondContact O-CG2 3.43Å; L655-V659 PolarHBondContact O-N 3.48Å; V656-V659 PolarHBondContact O-N 2.81Å; V659-E662 WeakPolarHBondContact O-CA 3.41Å; V659-E662 PolarHBondContact O-N 2.99Å; V659-W664 HydrophobicContact CG2-CB 3.97Å; V659-W664 HydrophobicContact CG2-CG 4Å; V659-L671 HydrophobicContact CG2-CD1 4.44Å; V659-L671 HydrophobicContact CG2-CD2 3.96Å; V659-L671 HydrophobicContact CG2-CG 4.17Å; V659-V675 HydrophobicContact CG2-CG2 4.27Å
660V94.6Very high94.1Very high45 Ų4529.9 Ų29.927%0.27314%0.139SC..Hα-helixtrans-62.4-39.8173.3165.20000112.4V656 A657 E662 T738 E742 K840V656-V660 WeakPolarHBondContact O-CB 3.36Å; V656-V660 WeakPolarHBondContact O-CG2 3.3Å; V656-V660 PolarHBondContact O-N 3.2Å; A657-V660 PolarHBondContact O-N 3.41Å; V660-E662 PolarHBondContact O-N 3.2Å; V660-E662 VanDerWaalsContact O-N 3.08Å; V660-T738 HydrophobicContact CG1-CG2 3.75Å; V660-E742 HydrophobicContact CG1-CG 4.1Å; V660-E742 WeakPolarHBondContact CG1-OE1 3.41Å; V660-K840 VanDerWaalsContact CG1-NZ 3.27Å
661A95.1Very high93.8Very high4 Ų430.1 Ų30.13%0.03314%0.141CC..THydrogen-bonded Turntrans-72.111.3171.400000113.5A657 Q658 M663 Q735 T738 L739A657-A661 WeakPolarHBondContact O-CB 3.47Å; A657-A661 PolarHBondContact O-N 3.16Å; Q658-A661 CarbonylContact O-C 3.48Å; Q658-A661 PolarHBondContact O-N 3Å; A661-M663 HydrophobicContact CB-CG 4.17Å; A661-M663 HydrophobicContact CB-SD 4.18Å; A661-M663 PolarHBondContact O-N 2.98Å; A661-M663 VanDerWaalsContact O-N 3.09Å; A661-Q735 WeakPolarHBondContact O-CG 3.4Å; A661-T738 HydrophobicContact CB-CG2 3.92Å; A661-L739 HydrophobicContact CB-CD2 4.01Å; A661-L739 HydrophobicContact CB-CG 4.04Å
662E93.6Very high93.5Very high69 Ų6934 Ų3432%0.32216%0.161SC..THydrogen-bonded Turntrans64.613173.1-48.6-171.7115.100114.6Q658 V659 V660 W664 R665 K734Q658-E662 PolarHBondContact O-N 2.72Å; V659-E662 WeakPolarHBondContact O-CA 3.41Å; V659-E662 PolarHBondContact O-N 2.99Å; V660-E662 PolarHBondContact O-N 3.2Å; V660-E662 VanDerWaalsContact O-N 3.08Å; E662-W664 VanDerWaalsContact C-N 3.27Å; E662-W664 PolarHBondContact O-N 3.07Å; E662-R665 HydrophobicContact CB-CG 4.32Å; E662-R665 VanDerWaalsContact CD-CZ 3.43Å; E662-R665 WeakPolarHBondContact O-CD 3.33Å; E662-R665 WeakPolarHBondContact O-CG 3.48Å; E662-R665 IonicContact OE1-CZ 3.79Å; E662-R665 IonicContact OE1-NE 2.88Å; E662-R665 IonicContact OE1-NH2 3.45Å; E662-R665 PolarHBondContact OE1-NH2 3.31Å; E662-R665 IonicContact OE2-CZ 3.33Å; E662-R665 IonicContact OE2-NH1 3.77Å; E662-R665 IonicContact OE2-NH2 2.65Å; E662-R665 PolarHBondContact OE2-NH2 3.05Å; E662-K734 IonicContact OE2-NZ 2.57Å; E662-K734 PolarHBondContact OE2-NZ 3.11Å
663M94.1Very high93.3Very high20 Ų2035.8 Ų35.810%0.09917%0.174CC..THydrogen-bonded Turntrans-70.7-24.2-175.6-63.2171.165.500112.5R520 Q658 A661 Q735 L739R520-M663 PolarHBondContact NE-O 2.78Å; R520-M663 PolarHBondContact NH2-O 3.43Å; R520-M663 VanDerWaalsContact NH2-O 3.13Å; Q658-M663 HydrophobicContact CB-CB 4.36Å; Q658-M663 HydrophobicContact CB-SD 3.82Å; Q658-M663 HydrophobicContact CG-CE 4.15Å; Q658-M663 HydrophobicContact CG-SD 3.66Å; Q658-M663 WeakPolarHBondContact O-CB 3.26Å; Q658-M663 PolarHBondContact O-N 3.3Å; A661-M663 HydrophobicContact CB-CG 4.17Å; A661-M663 HydrophobicContact CB-SD 4.18Å; A661-M663 PolarHBondContact O-N 2.98Å; A661-M663 VanDerWaalsContact O-N 3.09Å; M663-Q735 HydrophobicContact CG-CG 4.05Å; M663-L739 HydrophobicContact SD-CD1 3.99Å; M663-L739 HydrophobicContact SD-CD2 4.47Å
664W94Very high93Very high8 Ų835.9 Ų35.93%0.0317%0.174CC..THydrogen-bonded Turntrans-105.811.9-171.6-68.276.6000114.8I518 R520 V600 V605 L655 Q658 V659 E662 R666 N667 L671I518-W664 HydrophobicContact CD1-CE3 4.4Å; I518-W664 HydrophobicContact CD1-CZ3 3.89Å; I518-W664 HydrophobicContact CG1-CH2 4.43Å; I518-W664 HydrophobicContact CG1-CZ3 4.02Å; R520-W664 VanDerWaalsContact CA-CZ3 3.41Å; R520-W664 HydrophobicContact CB-CD2 4.04Å; R520-W664 HydrophobicContact CB-CE3 3.91Å; R520-W664 HydrophobicContact CB-CH2 3.73Å; R520-W664 HydrophobicContact CB-CZ2 3.84Å; R520-W664 HydrophobicContact CB-CZ3 3.76Å; R520-W664 HydrophobicContact CG-CD2 3.89Å; R520-W664 HydrophobicContact CG-CE3 4.11Å; R520-W664 HydrophobicContact CG-CG 4.32Å; R520-W664 HydrophobicContact CG-CZ2 4.4Å; R520-W664 HydrophobicContact CG-CZ3 4.47Å; V600-W664 HydrophobicContact CG1-CZ2 4.23Å; V600-W664 VanDerWaalsContact O-CZ2 3.24Å; V600-W664 WeakPolarHBondContact O-CZ2 3.25Å; V605-W664 HydrophobicContact CG1-CH2 3.76Å; V605-W664 HydrophobicContact CG1-CZ2 4.26Å; L655-W664 HydrophobicContact CD1-CD2 3.91Å; L655-W664 HydrophobicContact CD1-CE3 4.17Å; L655-W664 HydrophobicContact CD1-CH2 3.83Å; L655-W664 HydrophobicContact CD1-CZ2 3.53Å; L655-W664 HydrophobicContact CD1-CZ3 4.13Å; Q658-W664 VanDerWaalsContact CB-NE1 3.32Å; V659-W664 HydrophobicContact CG2-CB 3.97Å; V659-W664 HydrophobicContact CG2-CG 4Å; E662-W664 VanDerWaalsContact C-N 3.27Å; E662-W664 PolarHBondContact O-N 3.07Å; W664-R666 PolarHBondContact O-N 2.78Å; W664-N667 HydrophobicContact CE3-CB 4.38Å; W664-N667 WeakPolarHBondContact O-CB 3.46Å; W664-N667 PolarHBondContact O-N 3.49Å; W664-L671 HydrophobicContact CB-CD2 3.76Å; W664-L671 HydrophobicContact CD2-CD2 4.04Å; W664-L671 HydrophobicContact CE3-CD2 3.58Å; W664-L671 HydrophobicContact CG-CD2 4.15Å; W664-L671 HydrophobicContact CZ3-CD2 4.44Å
665R89.6Confident92.8Very high163 Ų16336.5 Ų36.562%0.61518%0.178SC*.THydrogen-bonded Turntrans-50.7-15-179.7-77.6169.6165.9158.9-6.8116.4H525 E662H525-R665 PolarHBondContact ND1-O 2.77Å; E662-R665 HydrophobicContact CB-CG 4.32Å; E662-R665 VanDerWaalsContact CD-CZ 3.43Å; E662-R665 WeakPolarHBondContact O-CD 3.33Å; E662-R665 WeakPolarHBondContact O-CG 3.48Å; E662-R665 IonicContact OE1-CZ 3.79Å; E662-R665 IonicContact OE1-NE 2.88Å; E662-R665 IonicContact OE1-NH2 3.45Å; E662-R665 PolarHBondContact OE1-NH2 3.31Å; E662-R665 IonicContact OE2-CZ 3.33Å; E662-R665 IonicContact OE2-NH1 3.77Å; E662-R665 IonicContact OE2-NH2 2.65Å; E662-R665 PolarHBondContact OE2-NH2 3.05Å
666R88.7Confident92.6Very high115 Ų11542.1 Ų42.143%0.43420%0.203SC..THydrogen-bonded Turntrans-95.3-3.6-178.6-62.8-171.8-172.1159.611.4114.2Q521 V522 G523 I526 W664 G668Q521-R666 HydrophobicContact CB-CB 3.83Å; Q521-R666 WeakPolarHBondContact O-CB 3.3Å; V522-R666 VanDerWaalsContact C-NH1 3.28Å; V522-R666 PolarHBondContact O-NH1 2.8Å; G523-R666 VanDerWaalsContact O-CD 3.22Å; G523-R666 WeakPolarHBondContact O-CD 3.45Å; G523-R666 PolarHBondContact O-NH1 2.81Å; I526-R666 PolarHBondContact N-O 3.3Å; W664-R666 PolarHBondContact O-N 2.78Å; R666-G668 VanDerWaalsContact C-N 3.33Å; R666-G668 PolarHBondContact O-N 3.43Å
667N90.9Very high92.4Very high15 Ų1544.5 Ų44.58%0.0821%0.211CC..SBendtrans-91.122.3-179.8-75.676000114.1R519 Q521 I526 W664 L671R519-N667 PolarHBondContact O-ND2 2.67Å; Q521-N667 PolarHBondContact N-OD1 3.41Å; I526-N667 WeakPolarHBondContact CD1-O 3.38Å; W664-N667 HydrophobicContact CE3-CB 4.38Å; W664-N667 WeakPolarHBondContact O-CB 3.46Å; W664-N667 PolarHBondContact O-N 3.49Å; N667-L671 HydrophobicContact CB-CB 4.33Å; N667-L671 HydrophobicContact CB-CD2 3.71Å
668G87.2Confident92.2Very high7 Ų744.5 Ų44.57%0.07221%0.211CC..THydrogen-bonded Turntrans70.9-170174.700000115.4D529 R666D529-G668 VanDerWaalsContact OD1-CA 3.29Å; D529-G668 WeakPolarHBondContact OD1-CA 3.48Å; R666-G668 VanDerWaalsContact C-N 3.33Å; R666-G668 PolarHBondContact O-N 3.43Å
669L87.4Confident92.1Very high117 Ų11748.5 Ų48.561%0.61323%0.23SC*.THydrogen-bonded Turntrans-86-23.5177.7-67177.1000112.1D529 L671 I672 S673D529-L669 PolarHBondContact OD1-N 2.79Å; D529-L669 PolarHBondContact OD2-N 2.75Å; D529-L669 VanDerWaalsContact OD2-N 3.16Å; L669-L671 VanDerWaalsContact C-N 3.32Å; L669-L671 PolarHBondContact O-N 3.26Å; L669-I672 HydrophobicContact CD2-CD1 4.27Å; L669-I672 PolarHBondContact O-N 2.87Å; L669-S673 PolarHBondContact O-N 3.23Å; L669-S673 PolarHBondContact O-OG 3.26Å
670S88.6Confident91.9Very high3 Ų348.6 Ų48.62%0.02123%0.229CC..Hα-helixtrans-51.9-48.2177.5174.60000111.8D529 P530 W532 I672 S673 Q674D529-S670 VanDerWaalsContact OD1-CB 3.29Å; D529-S670 WeakPolarHBondContact OD1-CB 3.5Å; D529-S670 PolarHBondContact OD1-N 2.87Å; P530-S670 PolarHBondContact O-OG 3.42Å; W532-S670 WeakPolarHBondContact CB-OG 3.47Å; S670-I672 PolarHBondContact O-N 3.33Å; S670-S673 WeakPolarHBondContact O-CB 3.46Å; S670-S673 PolarHBondContact O-N 3.39Å; S670-Q674 WeakPolarHBondContact O-CG 3.27Å; S670-Q674 PolarHBondContact O-N 2.93Å; S670-Q674 PolarHBondContact OG-NE2 2.94Å
671L91.4Very high91.8Very high7 Ų747.6 Ų47.64%0.03722%0.223CC..Hα-helixtrans-62.1-39.6176.817753.7000113.2I518 V659 W664 N667 L669 S673 Q674 V675I518-L671 HydrophobicContact CD1-CD1 3.32Å; I518-L671 HydrophobicContact CD1-CD2 4.01Å; I518-L671 HydrophobicContact CD1-CG 4.22Å; V659-L671 HydrophobicContact CG2-CD1 4.44Å; V659-L671 HydrophobicContact CG2-CD2 3.96Å; V659-L671 HydrophobicContact CG2-CG 4.17Å; W664-L671 HydrophobicContact CB-CD2 3.76Å; W664-L671 HydrophobicContact CD2-CD2 4.04Å; W664-L671 HydrophobicContact CE3-CD2 3.58Å; W664-L671 HydrophobicContact CG-CD2 4.15Å; W664-L671 HydrophobicContact CZ3-CD2 4.44Å; N667-L671 HydrophobicContact CB-CB 4.33Å; N667-L671 HydrophobicContact CB-CD2 3.71Å; L669-L671 VanDerWaalsContact C-N 3.32Å; L669-L671 PolarHBondContact O-N 3.26Å; L671-S673 VanDerWaalsContact C-N 3.33Å; L671-Q674 PolarHBondContact O-N 3.2Å; L671-V675 HydrophobicContact CD1-CG2 4.08Å; L671-V675 WeakPolarHBondContact O-CG2 3.34Å; L671-V675 PolarHBondContact O-N 3.49Å
672I91Very high91.4Very high96 Ų9652.4 Ų52.449%0.49224%0.243SC..Hα-helixtrans-67.1-40.3179.7-59.2179.8000109.8L669 S670 V675 F676L669-I672 HydrophobicContact CD2-CD1 4.27Å; L669-I672 PolarHBondContact O-N 2.87Å; S670-I672 PolarHBondContact O-N 3.33Å; I672-V675 PolarHBondContact O-N 3.22Å; I672-F676 WeakPolarHBondContact O-CB 3.37Å; I672-F676 PolarHBondContact O-N 3.17Å
673S91.8Very high91.2Very high39 Ų3949.4 Ų49.427%0.27323%0.23SC..Hα-helixtrans-62.1-47.2173.6-59.90000111.7L669 S670 L671 V675 F676 Y677L669-S673 PolarHBondContact O-N 3.23Å; L669-S673 PolarHBondContact O-OG 3.26Å; S670-S673 WeakPolarHBondContact O-CB 3.46Å; S670-S673 PolarHBondContact O-N 3.39Å; L671-S673 VanDerWaalsContact C-N 3.33Å; S673-V675 PolarHBondContact O-N 3.06Å; S673-F676 WeakPolarHBondContact O-CB 2.9Å; S673-F676 PolarHBondContact O-N 3.49Å; S673-F676 VanDerWaalsContact O-N 3.15Å; S673-Y677 VanDerWaalsContact O-CD2 3.28Å; S673-Y677 WeakPolarHBondContact O-CD2 2.91Å; S673-Y677 PolarHBondContact O-N 3.13Å
674Q92.7Very high91.2Very high8 Ų849.3 Ų49.34%0.03723%0.228CC..Hα-helixtrans-57.2-46.4175.9-75.31804300112.5W532 I607 S670 L671 F676 Y677 Y678W532-Q674 HydrophobicContact CB-CG 4.09Å; W532-Q674 HydrophobicContact CD2-CG 4.34Å; W532-Q674 HydrophobicContact CE3-CG 4.11Å; W532-Q674 HydrophobicContact CG-CG 4.33Å; I607-Q674 HydrophobicContact CD1-CB 3.73Å; I607-Q674 HydrophobicContact CD1-CG 4.35Å; I607-Q674 WeakPolarHBondContact CD1-O 3.29Å; S670-Q674 WeakPolarHBondContact O-CG 3.27Å; S670-Q674 PolarHBondContact O-N 2.93Å; S670-Q674 PolarHBondContact OG-NE2 2.94Å; L671-Q674 PolarHBondContact O-N 3.2Å; Q674-F676 VanDerWaalsContact C-N 3.33Å; Q674-F676 PolarHBondContact O-N 3.49Å; Q674-Y677 PolarHBondContact O-N 3.48Å; Q674-Y678 WeakPolarHBondContact O-CB 2.91Å; Q674-Y678 PolarHBondContact O-N 3.31Å
675V93.2Very high91.1Very high12 Ų1252.3 Ų52.37%0.07324%0.243CC..Hα-helixtrans-65.2-35.5176.2170.50000112V656 V659 L671 I672 S673V656-V675 HydrophobicContact CG1-CG1 4.05Å; V656-V675 HydrophobicContact CG2-CG1 4.06Å; V656-V675 HydrophobicContact CG2-CG2 4.27Å; V659-V675 HydrophobicContact CG2-CG2 4.27Å; L671-V675 HydrophobicContact CD1-CG2 4.08Å; L671-V675 WeakPolarHBondContact O-CG2 3.34Å; L671-V675 PolarHBondContact O-N 3.49Å; I672-V675 PolarHBondContact O-N 3.22Å; S673-V675 PolarHBondContact O-N 3.06Å
676F92.7Very high91.2Very high118 Ų11845.1 Ų45.152%0.51822%0.216SC..Hα-helixtrans-61.7-50.7173170.4-93000111.5I672 S673 Q674 Y678 Q679 D680I672-F676 WeakPolarHBondContact O-CB 3.37Å; I672-F676 PolarHBondContact O-N 3.17Å; S673-F676 WeakPolarHBondContact O-CB 2.9Å; S673-F676 PolarHBondContact O-N 3.49Å; S673-F676 VanDerWaalsContact O-N 3.15Å; Q674-F676 VanDerWaalsContact C-N 3.33Å; Q674-F676 PolarHBondContact O-N 3.49Å; F676-Y678 VanDerWaalsContact C-N 3.34Å; F676-Y678 PolarHBondContact O-N 3.47Å; F676-Q679 PolarHBondContact O-N 3.35Å; F676-D680 HydrophobicContact CE1-CB 4.36Å; F676-D680 PolarHBondContact O-N 3.19Å
677Y92.9Very high91.5Very high58 Ų5839.7 Ų39.723%0.22720%0.196CC..Hα-helixtrans-64.2-36.8178.9-81.3-78.9000112.9W532 I536 S673 Q674 Q679 D680 C683W532-Y677 AromaticContact CH2-CD2 3.83Å; W532-Y677 HydrophobicContact CH2-CD2 3.83Å; W532-Y677 AromaticContact CH2-CE2 3.42Å; W532-Y677 HydrophobicContact CH2-CE2 3.42Å; W532-Y677 VanDerWaalsContact CH2-CE2 3.42Å; W532-Y677 AromaticContact CZ3-CD2 3.55Å; W532-Y677 HydrophobicContact CZ3-CD2 3.55Å; W532-Y677 AromaticContact CZ3-CE2 3.63Å; W532-Y677 HydrophobicContact CZ3-CE2 3.63Å; I536-Y677 HydrophobicContact CG2-CD1 4.07Å; I536-Y677 HydrophobicContact CG2-CD2 4.49Å; I536-Y677 HydrophobicContact CG2-CG 4.02Å; S673-Y677 VanDerWaalsContact O-CD2 3.28Å; S673-Y677 WeakPolarHBondContact O-CD2 2.91Å; S673-Y677 PolarHBondContact O-N 3.13Å; Q674-Y677 PolarHBondContact O-N 3.48Å; Y677-Q679 PolarHBondContact O-N 3.09Å; Y677-Q679 VanDerWaalsContact O-N 3.13Å; Y677-D680 PolarHBondContact O-N 2.9Å; Y677-D680 VanDerWaalsContact O-N 3.12Å; Y677-C683 PolarHBondContact O-SG 3.24Å
678Y94.6Very high91.8Very high0 Ų039.7 Ų39.70%020%0.195CC..Hα-helixtrans-52.2-34.3174.4172.9-115.3000113.5C652 V656 Q674 F676 M687 Y688 D691C652-Y678 VanDerWaalsContact SG-CZ 3.53Å; V656-Y678 HydrophobicContact CG2-CD1 3.73Å; V656-Y678 HydrophobicContact CG2-CE1 3.72Å; Q674-Y678 WeakPolarHBondContact O-CB 2.91Å; Q674-Y678 PolarHBondContact O-N 3.31Å; F676-Y678 VanDerWaalsContact C-N 3.34Å; F676-Y678 PolarHBondContact O-N 3.47Å; Y678-M687 HydrophobicContact CD2-CB 3.86Å; Y678-M687 HydrophobicContact CD2-CE 4.19Å; Y678-M687 HydrophobicContact CE2-CB 4.14Å; Y678-Y688 HydrophobicContact CD1-CD2 4.42Å; Y678-Y688 AromaticContact CE1-CD2 3.56Å; Y678-Y688 HydrophobicContact CE1-CD2 3.56Å; Y678-Y688 HydrophobicContact CE1-CE2 4.37Å; Y678-Y688 HydrophobicContact CE1-CG 4.36Å; Y678-Y688 AromaticContact CZ-CD2 3.74Å; Y678-Y688 WeakPolarHBondContact O-CB 3.39Å; Y678-D691 VanDerWaalsContact CE2-OD2 3.22Å; Y678-D691 WeakPolarHBondContact CE2-OD2 3.44Å; Y678-D691 PolarHBondContact OH-OD2 2.93Å
679Q93Very high92.3Very high85 Ų8539.9 Ų39.940%0.39719%0.194SC..Hα-helixtrans-102.5-7.8-179.5-56.5-172.8-55.300113.9F676 Y677F676-Q679 PolarHBondContact O-N 3.35Å; Y677-Q679 PolarHBondContact O-N 3.09Å; Y677-Q679 VanDerWaalsContact O-N 3.13Å
680D92.9Very high92.7Very high32 Ų3235.2 Ų35.217%0.17117%0.169CC..SBendtrans-70.3145-177.2-176.1-99.9000112.5F676 Y677 K682 C683 R684F676-D680 HydrophobicContact CE1-CB 4.36Å; F676-D680 PolarHBondContact O-N 3.19Å; Y677-D680 PolarHBondContact O-N 2.9Å; Y677-D680 VanDerWaalsContact O-N 3.12Å; D680-K682 PolarHBondContact O-N 2.98Å; D680-K682 VanDerWaalsContact OD1-CB 3.22Å; D680-K682 WeakPolarHBondContact OD1-CB 3.42Å; D680-K682 WeakPolarHBondContact OD1-CD 3.45Å; D680-K682 WeakPolarHBondContact OD1-CG 3.46Å; D680-K682 PolarHBondContact OD1-N 3.34Å; D680-C683 PolarHBondContact O-N 3.07Å; D680-C683 VanDerWaalsContact O-N 3.08Å; D680-R684 WeakPolarHBondContact O-CB 3.29Å; D680-R684 PolarHBondContact O-N 3.44Å
681V91.8Very high93.2Very high24 Ų2435.1 Ų35.115%0.14517%0.168CC..THydrogen-bonded Turntrans-55.4-27-178.1670000113.6C683 L790V681-C683 PolarHBondContact O-N 3.27Å; V681-L790 VanDerWaalsContact CG2-C 3.42Å
682K88.4Confident93.5Very high105 Ų10535 Ų3546%0.45717%0.167SC..THydrogen-bonded Turntrans-63.3-25.3179.2-68.9170.4-176.2176.80113.9M540 K543 D680M540-K682 HydrophobicContact CE-CB 4.4Å; M540-K682 HydrophobicContact CE-CD 4.09Å; K543-K682 VanDerWaalsContact CD-O 3.29Å; K543-K682 WeakPolarHBondContact CD-O 3.23Å; K543-K682 PolarHBondContact NZ-O 3.25Å; D680-K682 PolarHBondContact O-N 2.98Å; D680-K682 VanDerWaalsContact OD1-CB 3.22Å; D680-K682 WeakPolarHBondContact OD1-CB 3.42Å; D680-K682 WeakPolarHBondContact OD1-CD 3.45Å; D680-K682 WeakPolarHBondContact OD1-CG 3.46Å; D680-K682 PolarHBondContact OD1-N 3.34Å
683C88.9Confident93.9Very high6 Ų630.7 Ų30.74%0.04115%0.146CC..THydrogen-bonded Turntrans-144.6-9.1-172.439.30000116.1Y677 D680 V681 E685 E686 M687Y677-C683 PolarHBondContact O-SG 3.24Å; D680-C683 PolarHBondContact O-N 3.07Å; D680-C683 VanDerWaalsContact O-N 3.08Å; V681-C683 PolarHBondContact O-N 3.27Å; C683-E685 PolarHBondContact O-N 3.29Å; C683-E685 VanDerWaalsContact O-N 3.11Å; C683-E686 CarbonylContact O-C 3.56Å; C683-E686 PolarHBondContact O-N 3.09Å; C683-M687 HydrophobicContact CB-CG 4.34Å; C683-M687 HydrophobicContact CB-SD 3.9Å; C683-M687 WeakPolarHBondContact O-CG 3.49Å; C683-M687 PolarHBondContact O-N 2.89Å; C683-M687 VanDerWaalsContact O-N 3.13Å
684R92.6Very high94.2Very high17 Ų1728.9 Ų28.96%0.06413%0.133CC..G310 helixtrans-50.8-38.3-178.770.8-173.3-168.4-152.14.3114.1D680 E686 M687 Y688 D689 E771 H837D680-R684 WeakPolarHBondContact O-CB 3.29Å; D680-R684 PolarHBondContact O-N 3.44Å; R684-E686 VanDerWaalsContact C-N 3.27Å; R684-E686 PolarHBondContact O-N 3.44Å; R684-M687 CarbonylContact O-C 3.52Å; R684-M687 PolarHBondContact O-N 3.43Å; R684-Y688 PolarHBondContact O-N 2.99Å; R684-D689 PolarHBondContact O-N 3.02Å; R684-E771 IonicContact CZ-OE1 3.69Å; R684-E771 IonicContact NH2-OE1 3.09Å; R684-E771 PolarHBondContact NH2-OE1 2.73Å; R684-E771 IonicContact NH2-OE2 2.77Å; R684-E771 PolarHBondContact NH2-OE2 3.48Å; R684-H837 VanDerWaalsContact CD-CD2 3.48Å; R684-H837 WeakPolarHBondContact CD-CD2 3.31Å; R684-H837 PolarHBondContact NE-CD2 3.14Å; R684-H837 VanDerWaalsContact NE-CD2 3.32Å; R684-H837 PolarHBondContact NE-ND1 2.86Å; R684-H837 PolarHBondContact NH2-ND1 2.95Å; R684-H837 VanDerWaalsContact NH2-ND1 3.14Å
685E92.1Very high94.5Very high71 Ų7128.5 Ų28.533%0.33213%0.131SC..G310 helixtrans-58.9-31.6178.3-69.7-164.5138.400114C683 K690 P791C683-E685 PolarHBondContact O-N 3.29Å; C683-E685 VanDerWaalsContact O-N 3.11Å; E685-K690 WeakPolarHBondContact O-CG 3.38Å; E685-K690 PolarHBondContact O-NZ 2.83Å; E685-P791 VanDerWaalsContact CD-CB 3.4Å; E685-P791 HydrophobicContact CG-CB 4.03Å; E685-P791 HydrophobicContact CG-CG 4.4Å; E685-P791 VanDerWaalsContact OE1-CG 3.3Å; E685-P791 WeakPolarHBondContact OE1-CG 3.42Å; E685-P791 WeakPolarHBondContact OE2-CB 3.14Å
686E92.8Very high94.7Very high13 Ų1328 Ų286%0.06113%0.128CC..G310 helixtrans-108.212.4176.2-64.9-57.2131.200112.2Q550 R613 C683 R684 K690Q550-E686 PolarHBondContact NE2-OE2 3.22Å; R613-E686 WeakPolarHBondContact CD-O 3.41Å; C683-E686 CarbonylContact O-C 3.56Å; C683-E686 PolarHBondContact O-N 3.09Å; R684-E686 VanDerWaalsContact C-N 3.27Å; R684-E686 PolarHBondContact O-N 3.44Å; E686-K690 VanDerWaalsContact CD-NZ 3.27Å; E686-K690 WeakPolarHBondContact OE1-CE 3.22Å; E686-K690 IonicContact OE1-NZ 2.65Å; E686-K690 PolarHBondContact OE1-NZ 3.34Å; E686-K690 WeakPolarHBondContact OE2-CE 3.48Å; E686-K690 IonicContact OE2-NZ 2.99Å; E686-K690 PolarHBondContact OE2-NZ 3.44Å
687M95.1Very high95Very high1 Ų122.5 Ų22.51%0.00510%0.104CC..THydrogen-bonded Turntrans-129.1-97177.6-63.5-172.385.600110.6Q539 I607 R613 Y678 C683 R684 D689 K690 D691Q539-M687 HydrophobicContact CG-CE 4.2Å; Q539-M687 HydrophobicContact CG-SD 3.99Å; I607-M687 HydrophobicContact CD1-CE 4.26Å; R613-M687 PolarHBondContact NE-O 3.43Å; Y678-M687 HydrophobicContact CD2-CB 3.86Å; Y678-M687 HydrophobicContact CD2-CE 4.19Å; Y678-M687 HydrophobicContact CE2-CB 4.14Å; C683-M687 HydrophobicContact CB-CG 4.34Å; C683-M687 HydrophobicContact CB-SD 3.9Å; C683-M687 WeakPolarHBondContact O-CG 3.49Å; C683-M687 PolarHBondContact O-N 2.89Å; C683-M687 VanDerWaalsContact O-N 3.13Å; R684-M687 CarbonylContact O-C 3.52Å; R684-M687 PolarHBondContact O-N 3.43Å; M687-D689 PolarHBondContact O-N 3.08Å; M687-K690 PolarHBondContact O-N 2.91Å; M687-D691 PolarHBondContact O-N 3.15Å
688Y96.8Very high95.2Very high15 Ų1519.7 Ų19.76%0.0599%0.093CC..Hα-helixtrans-51.7-49-177.4-178.2-120.2000114.2L653 Y678 R684 K690 D691 I692 Y749 Y836L653-Y688 HydrophobicContact CD2-CD2 3.9Å; L653-Y688 HydrophobicContact CD2-CE2 3.55Å; Y678-Y688 HydrophobicContact CD1-CD2 4.42Å; Y678-Y688 AromaticContact CE1-CD2 3.56Å; Y678-Y688 HydrophobicContact CE1-CD2 3.56Å; Y678-Y688 HydrophobicContact CE1-CE2 4.37Å; Y678-Y688 HydrophobicContact CE1-CG 4.36Å; Y678-Y688 AromaticContact CZ-CD2 3.74Å; Y678-Y688 WeakPolarHBondContact O-CB 3.39Å; R684-Y688 PolarHBondContact O-N 2.99Å; Y688-K690 VanDerWaalsContact C-N 3.34Å; Y688-K690 PolarHBondContact O-N 2.96Å; Y688-D691 WeakPolarHBondContact O-CB 3.45Å; Y688-D691 PolarHBondContact O-N 2.84Å; Y688-D691 VanDerWaalsContact O-N 3.14Å; Y688-I692 HydrophobicContact CE2-CD1 4.49Å; Y688-I692 HydrophobicContact CE2-CG1 4.48Å; Y688-I692 PolarHBondContact O-N 2.68Å; Y688-I692 VanDerWaalsContact O-N 3.12Å; Y688-Y749 WeakPolarHBondContact OH-CD2 3.38Å; Y688-Y749 WeakPolarHBondContact OH-CE2 3.23Å; Y688-Y836 HydrophobicContact CD1-CD2 4.26Å; Y688-Y836 AromaticContact CE1-CD2 3.79Å; Y688-Y836 HydrophobicContact CE1-CD2 3.79Å
689D97.1Very high95.3Very high10 Ų1019.9 Ų19.95%0.0539%0.094CC..Hα-helixtrans-61.9-41.3-178.1-71.150000111.7R684 M687 D691 I692 I693 Y836 H837R684-D689 PolarHBondContact O-N 3.02Å; M687-D689 PolarHBondContact O-N 3.08Å; D689-D691 VanDerWaalsContact C-N 3.3Å; D689-D691 PolarHBondContact O-N 3.14Å; D689-I692 PolarHBondContact O-N 3.08Å; D689-I693 WeakPolarHBondContact O-CB 3.45Å; D689-I693 WeakPolarHBondContact O-CD1 3.49Å; D689-I693 WeakPolarHBondContact O-CG1 3.29Å; D689-I693 PolarHBondContact O-N 3.01Å; D689-Y836 VanDerWaalsContact OD2-CE2 3.28Å; D689-Y836 WeakPolarHBondContact OD2-CE2 3.35Å; D689-Y836 PolarHBondContact OD2-OH 3.21Å; D689-H837 IonicContact OD1-CD2 3.75Å; D689-H837 IonicContact OD1-NE2 3.62Å; D689-H837 PolarHBondContact OD1-NE2 2.74Å; D689-H837 IonicContact OD2-CE1 3.5Å; D689-H837 PolarHBondContact OD2-CE1 3.25Å; D689-H837 IonicContact OD2-NE2 2.78Å; D689-H837 PolarHBondContact OD2-NE2 2.83Å
690K97.3Very high95.5Very high20 Ų2016 Ų169%0.0878%0.076CC..Hα-helixtrans-68.4-29.4177.9-66.1-66.1-167.3-66.70112.5R613 A616 E685 E686 M687 Y688 I693 M694R613-K690 HydrophobicContact CB-CB 3.58Å; R613-K690 HydrophobicContact CB-CG 4.02Å; R613-K690 HydrophobicContact CG-CB 3.6Å; A616-K690 HydrophobicContact CB-CD 4.41Å; E685-K690 WeakPolarHBondContact O-CG 3.38Å; E685-K690 PolarHBondContact O-NZ 2.83Å; E686-K690 VanDerWaalsContact CD-NZ 3.27Å; E686-K690 WeakPolarHBondContact OE1-CE 3.22Å; E686-K690 IonicContact OE1-NZ 2.65Å; E686-K690 PolarHBondContact OE1-NZ 3.34Å; E686-K690 WeakPolarHBondContact OE2-CE 3.48Å; E686-K690 IonicContact OE2-NZ 2.99Å; E686-K690 PolarHBondContact OE2-NZ 3.44Å; M687-K690 PolarHBondContact O-N 2.91Å; Y688-K690 VanDerWaalsContact C-N 3.34Å; Y688-K690 PolarHBondContact O-N 2.96Å; K690-I693 HydrophobicContact CD-CD1 4.31Å; K690-M694 PolarHBondContact O-N 3.06Å
691D98.3Very high95.6Very high0 Ų018.3 Ų18.30%09%0.088CC..Hα-helixtrans-69.9-43.3174.6-69-18000111R613 P649 L653 Y678 M687 Y688 D689 M694 L695R613-D691 WeakPolarHBondContact CG-OD1 3.23Å; R613-D691 IonicContact CZ-OD1 2.88Å; R613-D691 IonicContact CZ-OD2 2.75Å; R613-D691 IonicContact NE-OD1 3.31Å; R613-D691 PolarHBondContact NE-OD1 2.75Å; R613-D691 IonicContact NE-OD2 3.94Å; R613-D691 PolarHBondContact NE-OD2 3.3Å; R613-D691 IonicContact NH2-OD1 2.75Å; R613-D691 PolarHBondContact NH2-OD1 2.93Å; R613-D691 IonicContact NH2-OD2 3.2Å; R613-D691 PolarHBondContact NH2-OD2 3.23Å; P649-D691 HydrophobicContact CB-CB 3.83Å; L653-D691 HydrophobicContact CD1-CB 4.35Å; L653-D691 HydrophobicContact CG-CB 4.47Å; Y678-D691 VanDerWaalsContact CE2-OD2 3.22Å; Y678-D691 WeakPolarHBondContact CE2-OD2 3.44Å; Y678-D691 PolarHBondContact OH-OD2 2.93Å; M687-D691 PolarHBondContact O-N 3.15Å; Y688-D691 WeakPolarHBondContact O-CB 3.45Å; Y688-D691 PolarHBondContact O-N 2.84Å; Y688-D691 VanDerWaalsContact O-N 3.14Å; D689-D691 VanDerWaalsContact C-N 3.3Å; D689-D691 PolarHBondContact O-N 3.14Å; D691-M694 PolarHBondContact O-N 2.64Å; D691-L695 PolarHBondContact O-N 2.27Å; D691-L695 VanDerWaalsContact O-N 3.07Å
692I98.4Very high95.7Very high4 Ų418.2 Ų18.22%0.0219%0.087CC..Hα-helixtrans-60.8-44.7171.7-60.7-63.7000110.9L653 Y688 D689 M694 L695 Q696 Y749L653-I692 HydrophobicContact CD1-CD1 3.97Å; L653-I692 HydrophobicContact CD2-CD1 4.09Å; Y688-I692 HydrophobicContact CE2-CD1 4.49Å; Y688-I692 HydrophobicContact CE2-CG1 4.48Å; Y688-I692 PolarHBondContact O-N 2.68Å; Y688-I692 VanDerWaalsContact O-N 3.12Å; D689-I692 PolarHBondContact O-N 3.08Å; I692-M694 VanDerWaalsContact C-N 3.34Å; I692-M694 PolarHBondContact O-N 3.09Å; I692-L695 CarbonylContact O-C 3.59Å; I692-L695 WeakPolarHBondContact O-CB 3.4Å; I692-L695 PolarHBondContact O-N 2.79Å; I692-L695 VanDerWaalsContact O-N 3.13Å; I692-Q696 WeakPolarHBondContact O-CG 3.36Å; I692-Q696 PolarHBondContact O-N 2.92Å; I692-Y749 HydrophobicContact CD1-CD2 4.41Å
693I98.4Very high96Very high7 Ų716.7 Ų16.74%0.0368%0.083CC..Hα-helixtrans-61.1-40.8176.9-68.6162.9000111.2A616 V620 D689 K690 L695 Q696 I697 V756 V759A616-I693 HydrophobicContact CB-CG2 4.06Å; V620-I693 HydrophobicContact CG2-CG2 3.52Å; D689-I693 WeakPolarHBondContact O-CB 3.45Å; D689-I693 WeakPolarHBondContact O-CD1 3.49Å; D689-I693 WeakPolarHBondContact O-CG1 3.29Å; D689-I693 PolarHBondContact O-N 3.01Å; K690-I693 HydrophobicContact CD-CD1 4.31Å; I693-L695 VanDerWaalsContact C-N 3.31Å; I693-L695 PolarHBondContact O-N 1.95Å; I693-Q696 WeakPolarHBondContact O-CB 3.45Å; I693-Q696 PolarHBondContact O-N 3.49Å; I693-Q696 VanDerWaalsContact O-N 3.13Å; I693-I697 HydrophobicContact CG2-CD1 4.21Å; I693-I697 WeakPolarHBondContact O-CG1 3.41Å; I693-I697 PolarHBondContact O-N 3.32Å; I693-V756 HydrophobicContact CD1-CG1 4.07Å; I693-V756 HydrophobicContact CD1-CG2 4.34Å; I693-V759 HydrophobicContact CG1-CG2 4.23Å; I693-V759 HydrophobicContact CG2-CG2 4.36Å
694M98.3Very high96.4Very high1 Ų117.6 Ų17.61%0.0059%0.089CC..Hα-helixtrans-65.3-35.4175.8-170.860.985.500112S612 L615 A616 L645 P649 K690 D691 I692 Q696 I697 G698S612-M694 WeakPolarHBondContact O-CE 3.41Å; L615-M694 HydrophobicContact CB-CE 4.04Å; L615-M694 HydrophobicContact CD2-CE 4.12Å; L615-M694 HydrophobicContact CG-CE 4.27Å; A616-M694 HydrophobicContact CB-CB 4.24Å; A616-M694 HydrophobicContact CB-CE 3.98Å; L645-M694 HydrophobicContact CB-SD 4.17Å; P649-M694 HydrophobicContact CB-CB 4.32Å; P649-M694 HydrophobicContact CG-CB 3.79Å; P649-M694 HydrophobicContact CG-CG 3.83Å; K690-M694 PolarHBondContact O-N 3.06Å; D691-M694 PolarHBondContact O-N 2.64Å; I692-M694 VanDerWaalsContact C-N 3.34Å; I692-M694 PolarHBondContact O-N 3.09Å; M694-Q696 VanDerWaalsContact C-N 3.34Å; M694-I697 PolarHBondContact O-N 3.24Å; M694-I697 HydrophobicContact SD-CB 4.37Å; M694-I697 HydrophobicContact SD-CD1 4.05Å; M694-G698 PolarHBondContact O-N 3.04Å
695L98.5Very high96.6Very high0 Ų017.3 Ų17.30%09%0.089CC..Hα-helixtrans-67.6-32.8171.1-65.8-164.6000112.7V646 P649 L650 L653 D691 I692 I693 G698 A699 F707 V746 I750V646-L695 HydrophobicContact CB-CD2 3.93Å; V646-L695 HydrophobicContact CG1-CD2 4.3Å; P649-L695 HydrophobicContact CB-CD2 4.43Å; L650-L695 HydrophobicContact CB-CD2 4.08Å; L650-L695 HydrophobicContact CD1-CD1 4.24Å; L653-L695 HydrophobicContact CD1-CD1 3.47Å; L653-L695 VanDerWaalsContact CD1-CD1 3.47Å; L653-L695 HydrophobicContact CD1-CG 4.21Å; D691-L695 PolarHBondContact O-N 2.27Å; D691-L695 VanDerWaalsContact O-N 3.07Å; I692-L695 CarbonylContact O-C 3.59Å; I692-L695 WeakPolarHBondContact O-CB 3.4Å; I692-L695 PolarHBondContact O-N 2.79Å; I692-L695 VanDerWaalsContact O-N 3.13Å; I693-L695 VanDerWaalsContact C-N 3.31Å; I693-L695 PolarHBondContact O-N 1.95Å; L695-G698 PolarHBondContact O-N 2.96Å; L695-A699 VanDerWaalsContact O-CB 3.31Å; L695-A699 WeakPolarHBondContact O-CB 3.43Å; L695-A699 PolarHBondContact O-N 2.87Å; L695-F707 HydrophobicContact CB-CZ 4.19Å; L695-F707 HydrophobicContact CD2-CZ 4.49Å; L695-F707 WeakPolarHBondContact O-CZ 3.36Å; L695-V746 HydrophobicContact CD1-CG1 4.13Å; L695-I750 HydrophobicContact CB-CD1 3.85Å; L695-I750 HydrophobicContact CB-CG1 3.97Å; L695-I750 HydrophobicContact CD1-CD1 3.89Å
696Q98.5Very high96.8Very high2 Ų218.1 Ų18.11%0.0099%0.091CC..Hα-helixtrans-67-39.7171.6-70.9174.3-36.300112.4I692 I693 M694 G698 A699 S700 I750 E753 F875 V878I692-Q696 WeakPolarHBondContact O-CG 3.36Å; I692-Q696 PolarHBondContact O-N 2.92Å; I693-Q696 WeakPolarHBondContact O-CB 3.45Å; I693-Q696 PolarHBondContact O-N 3.49Å; I693-Q696 VanDerWaalsContact O-N 3.13Å; M694-Q696 VanDerWaalsContact C-N 3.34Å; Q696-G698 VanDerWaalsContact C-N 3.32Å; Q696-A699 PolarHBondContact O-N 3.23Å; Q696-S700 PolarHBondContact O-N 2.77Å; Q696-I750 HydrophobicContact CG-CB 4.45Å; Q696-I750 HydrophobicContact CG-CG2 4.04Å; Q696-I750 WeakPolarHBondContact CG-O 3.31Å; Q696-I750 PolarHBondContact NE2-O 3.22Å; Q696-E753 PolarHBondContact NE2-O 3.41Å; Q696-F875 HydrophobicContact CB-CD1 3.91Å; Q696-F875 HydrophobicContact CB-CE1 3.86Å; Q696-V878 HydrophobicContact CB-CG2 4.46Å; Q696-V878 VanDerWaalsContact O-CG2 3.3Å; Q696-V878 WeakPolarHBondContact O-CG2 3.36Å
697I97.8Very high97Very high1 Ų117.5 Ų17.51%0.0059%0.088CC..Hα-helixtrans-61.7-43.9171.1-63.4165.1000109.7A616 H619 I693 M694 S700 L701 F875A616-I697 HydrophobicContact CB-CD1 4.19Å; H619-I697 HydrophobicContact CB-CD1 3.5Å; H619-I697 VanDerWaalsContact CB-CD1 3.5Å; H619-I697 HydrophobicContact CB-CG1 4.35Å; I693-I697 HydrophobicContact CG2-CD1 4.21Å; I693-I697 WeakPolarHBondContact O-CG1 3.41Å; I693-I697 PolarHBondContact O-N 3.32Å; M694-I697 PolarHBondContact O-N 3.24Å; M694-I697 HydrophobicContact SD-CB 4.37Å; M694-I697 HydrophobicContact SD-CD1 4.05Å; I697-S700 PolarHBondContact O-N 3.08Å; I697-S700 PolarHBondContact O-OG 3.46Å; I697-S700 VanDerWaalsContact O-OG 3.06Å; I697-L701 HydrophobicContact CG2-CD1 3.89Å; I697-L701 WeakPolarHBondContact O-CG 3.33Å; I697-L701 PolarHBondContact O-N 3.08Å; I697-F875 HydrophobicContact CG1-CE1 3.64Å; I697-F875 HydrophobicContact CG1-CZ 3.74Å
698G96.8Very high97.1Very high0 Ų017.5 Ų17.50%09%0.089CC..Hα-helixtrans-54.9-53.3173.200000112.9M694 L695 Q696 S700 L701 M702M694-G698 PolarHBondContact O-N 3.04Å; L695-G698 PolarHBondContact O-N 2.96Å; Q696-G698 VanDerWaalsContact C-N 3.32Å; G698-S700 VanDerWaalsContact C-N 3.28Å; G698-S700 PolarHBondContact O-N 3.21Å; G698-L701 PolarHBondContact O-N 2.97Å; G698-M702 VanDerWaalsContact O-CB 3.29Å; G698-M702 WeakPolarHBondContact O-CB 3.38Å; G698-M702 WeakPolarHBondContact O-CG 3.45Å; G698-M702 PolarHBondContact O-N 3.14Å
699A97.8Very high97Very high3 Ų316.9 Ų16.93%0.0259%0.086CC..Hα-helixtrans-65-25.5-179.800000114.2L695 Q696 F707 I750 V878 L881L695-A699 VanDerWaalsContact O-CB 3.31Å; L695-A699 WeakPolarHBondContact O-CB 3.43Å; L695-A699 PolarHBondContact O-N 2.87Å; Q696-A699 PolarHBondContact O-N 3.23Å; A699-F707 HydrophobicContact CB-CD1 4.46Å; A699-F707 HydrophobicContact CB-CD2 4.49Å; A699-F707 HydrophobicContact CB-CE1 4.24Å; A699-F707 HydrophobicContact CB-CE2 4.27Å; A699-F707 HydrophobicContact CB-CZ 4.14Å; A699-I750 HydrophobicContact CB-CG2 4.09Å; A699-V878 HydrophobicContact CB-CG1 4.25Å; A699-V878 HydrophobicContact CB-CG2 4.09Å; A699-L881 HydrophobicContact CB-CD1 3.58Å; A699-L881 HydrophobicContact CB-CD2 4.42Å; A699-L881 HydrophobicContact CB-CG 4.07Å
700S96.6Very high96.9Very high3 Ų316.4 Ų16.42%0.0218%0.084CC..Hα-helixtrans-82-24.2176.776.60000113.5Q696 I697 G698 A874 K877Q696-S700 PolarHBondContact O-N 2.77Å; I697-S700 PolarHBondContact O-N 3.08Å; I697-S700 PolarHBondContact O-OG 3.46Å; I697-S700 VanDerWaalsContact O-OG 3.06Å; G698-S700 VanDerWaalsContact C-N 3.28Å; G698-S700 PolarHBondContact O-N 3.21Å; S700-A874 WeakPolarHBondContact CB-O 3.43Å; S700-A874 PolarHBondContact OG-O 2.97Å; S700-K877 WeakPolarHBondContact O-CB 3.48Å; S700-K877 VanDerWaalsContact O-CD 3.3Å; S700-K877 WeakPolarHBondContact O-CD 3.38Å
701L94.4Very high96.9Very high81 Ų8115.5 Ų15.542%0.4248%0.08SC..Hα-helixtrans-107.8-25.4-174.3-61.3176.9000114.4F640 V642 I697 G698F640-L701 HydrophobicContact CD1-CD1 4.34Å; F640-L701 HydrophobicContact CE1-CD1 3.51Å; F640-L701 HydrophobicContact CZ-CD1 3.88Å; V642-L701 HydrophobicContact CG1-CB 4.12Å; V642-L701 HydrophobicContact CG2-CB 3.76Å; V642-L701 HydrophobicContact CG2-CD1 4.16Å; I697-L701 HydrophobicContact CG2-CD1 3.89Å; I697-L701 WeakPolarHBondContact O-CG 3.33Å; I697-L701 PolarHBondContact O-N 3.08Å; G698-L701 PolarHBondContact O-N 2.97Å
702M94.7Very high96.7Very high23 Ų2315.8 Ų15.811%0.1138%0.081CC..SBendtrans-86.5163.3178.3-68178.758.400112.9V642 E643 V646 G698 F707 L710V642-M702 HydrophobicContact CB-CG 3.9Å; V642-M702 HydrophobicContact CB-SD 4.38Å; V642-M702 HydrophobicContact CG1-CG 3.68Å; V642-M702 HydrophobicContact CG1-SD 4.03Å; E643-M702 HydrophobicContact CG-CE 3.57Å; E643-M702 HydrophobicContact CG-SD 4.06Å; V646-M702 HydrophobicContact CG2-SD 4.39Å; G698-M702 VanDerWaalsContact O-CB 3.29Å; G698-M702 WeakPolarHBondContact O-CB 3.38Å; G698-M702 WeakPolarHBondContact O-CG 3.45Å; G698-M702 PolarHBondContact O-N 3.14Å; M702-F707 HydrophobicContact CB-CB 4.32Å; M702-F707 HydrophobicContact CE-CB 4.31Å; M702-F707 HydrophobicContact CE-CD2 4.42Å; M702-F707 HydrophobicContact SD-CD2 3.91Å; M702-L710 HydrophobicContact CE-CD2 4.41Å
703D95.6Very high96.5Very high72 Ų7216.6 Ų16.639%0.3859%0.085SC..  trans-63.3131.9161.4170.3-89.4000109.8N705 K706 F707D703-N705 VanDerWaalsContact C-N 3.3Å; D703-N705 PolarHBondContact O-N 3.34Å; D703-N705 WeakPolarHBondContact OD1-CA 3.48Å; D703-N705 VanDerWaalsContact OD1-CB 3.29Å; D703-N705 WeakPolarHBondContact OD1-CB 3.36Å; D703-N705 PolarHBondContact OD1-N 3.24Å; D703-K706 HydrophobicContact CB-CB 4.16Å; D703-K706 HydrophobicContact CB-CD 4.22Å; D703-K706 HydrophobicContact CB-CG 4.15Å; D703-K706 PolarHBondContact O-N 3.12Å; D703-K706 PolarHBondContact OD1-N 3.09Å; D703-F707 PolarHBondContact O-N 2.97Å
704P96.9Very high96.3Very high26 Ų2616.3 Ų16.317%0.1698%0.083CC..Hα-helixtrans-70.2-22.2-172.828.6-37.4000113.8L708 N880 L881 C884P704-L708 WeakPolarHBondContact O-CG 3.28Å; P704-L708 PolarHBondContact O-N 3.13Å; P704-N880 HydrophobicContact CB-CB 4.37Å; P704-N880 HydrophobicContact CG-CB 4.21Å; P704-L881 HydrophobicContact CB-CD2 3.81Å; P704-C884 HydrophobicContact CB-CB 3.82Å; P704-C884 HydrophobicContact CG-CB 3.9Å
705N96.8Very high96.2Very high11 Ų1116.3 Ų16.36%0.0598%0.083CC..Hα-helixtrans-76.1-46.1173.1-58.2-75.6000109.9H591 D703 F707 L708 L709 C884 D885 I886H591-N705 HydrophobicContact CB-CB 4.12Å; H591-N705 PolarHBondContact CE1-ND2 2.94Å; D703-N705 VanDerWaalsContact C-N 3.3Å; D703-N705 PolarHBondContact O-N 3.34Å; D703-N705 WeakPolarHBondContact OD1-CA 3.48Å; D703-N705 VanDerWaalsContact OD1-CB 3.29Å; D703-N705 WeakPolarHBondContact OD1-CB 3.36Å; D703-N705 PolarHBondContact OD1-N 3.24Å; N705-F707 VanDerWaalsContact C-N 3.32Å; N705-F707 PolarHBondContact O-N 3.37Å; N705-L708 PolarHBondContact O-N 3.21Å; N705-L709 WeakPolarHBondContact O-CG 3.39Å; N705-L709 PolarHBondContact O-N 2.89Å; N705-C884 WeakPolarHBondContact OD1-CB 3.46Å; N705-D885 PolarHBondContact OD1-N 3.16Å; N705-I886 HydrophobicContact CB-CG1 3.83Å; N705-I886 PolarHBondContact OD1-N 2.77Å
706K95.8Very high95.9Very high87 Ų8718.1 Ų18.138%0.3789%0.092SC..Hα-helixtrans-58.4-42174.5-71.8-171.9177.4-174.20112.4L593 D703 L709 L710L593-K706 HydrophobicContact CD1-CB 4.29Å; L593-K706 HydrophobicContact CD1-CG 4.46Å; D703-K706 HydrophobicContact CB-CB 4.16Å; D703-K706 HydrophobicContact CB-CD 4.22Å; D703-K706 HydrophobicContact CB-CG 4.15Å; D703-K706 PolarHBondContact O-N 3.12Å; D703-K706 PolarHBondContact OD1-N 3.09Å; K706-L709 PolarHBondContact O-N 3.42Å; K706-L710 PolarHBondContact O-N 3.14Å
707F96.9Very high95.7Very high1 Ų118 Ų180%0.0049%0.091CC..Hα-helixtrans-59.9-48.3176.3-176.8-90.1000111.8V646 L695 A699 M702 D703 N705 L709 L710 V711 I750 L881V646-F707 HydrophobicContact CG1-CE2 4.46Å; L695-F707 HydrophobicContact CB-CZ 4.19Å; L695-F707 HydrophobicContact CD2-CZ 4.49Å; L695-F707 WeakPolarHBondContact O-CZ 3.36Å; A699-F707 HydrophobicContact CB-CD1 4.46Å; A699-F707 HydrophobicContact CB-CD2 4.49Å; A699-F707 HydrophobicContact CB-CE1 4.24Å; A699-F707 HydrophobicContact CB-CE2 4.27Å; A699-F707 HydrophobicContact CB-CZ 4.14Å; M702-F707 HydrophobicContact CB-CB 4.32Å; M702-F707 HydrophobicContact CE-CB 4.31Å; M702-F707 HydrophobicContact CE-CD2 4.42Å; M702-F707 HydrophobicContact SD-CD2 3.91Å; D703-F707 PolarHBondContact O-N 2.97Å; N705-F707 VanDerWaalsContact C-N 3.32Å; N705-F707 PolarHBondContact O-N 3.37Å; F707-L709 PolarHBondContact O-N 3.04Å; F707-L710 WeakPolarHBondContact O-CB 3.15Å; F707-L710 PolarHBondContact O-N 3.05Å; F707-V711 HydrophobicContact CD1-CG2 4.26Å; F707-V711 HydrophobicContact CE1-CG2 3.89Å; F707-V711 HydrophobicContact CZ-CG2 4.31Å; F707-V711 WeakPolarHBondContact O-CG2 3.22Å; F707-V711 PolarHBondContact O-N 3.12Å; F707-I750 HydrophobicContact CE1-CD1 4.15Å; F707-I750 HydrophobicContact CZ-CD1 4.16Å; F707-L881 HydrophobicContact CB-CD2 4.22Å; F707-L881 HydrophobicContact CD1-CD1 4.07Å; F707-L881 HydrophobicContact CD1-CD2 3.58Å; F707-L881 HydrophobicContact CD1-CG 4.49Å; F707-L881 HydrophobicContact CE1-CD1 3.98Å; F707-L881 HydrophobicContact CE1-CD2 4.33Å; F707-L881 HydrophobicContact CG-CD2 4.18Å
708L97Very high95.3Very high1 Ų118.6 Ų18.61%0.00510%0.096CC..Hα-helixtrans-69.2-31.1177.5-65.9-172.2000113.5P704 N705 L710 V711 L712 L747 L881 C884 I886 M887 I890P704-L708 WeakPolarHBondContact O-CG 3.28Å; P704-L708 PolarHBondContact O-N 3.13Å; N705-L708 PolarHBondContact O-N 3.21Å; L708-L710 VanDerWaalsContact C-N 3.32Å; L708-V711 PolarHBondContact O-N 2.89Å; L708-L712 WeakPolarHBondContact O-CB 3.23Å; L708-L712 WeakPolarHBondContact O-CG 3.24Å; L708-L712 PolarHBondContact O-N 2.75Å; L708-L747 HydrophobicContact CD2-CD1 4.19Å; L708-L747 HydrophobicContact CD2-CD2 3.41Å; L708-L747 VanDerWaalsContact CD2-CD2 3.41Å; L708-L747 HydrophobicContact CD2-CG 4.47Å; L708-L881 HydrophobicContact CD2-CD2 4.18Å; L708-L881 HydrophobicContact CG-CD2 4.17Å; L708-C884 WeakPolarHBondContact CD1-SG 3.39Å; L708-I886 HydrophobicContact CB-CB 4.11Å; L708-I886 HydrophobicContact CB-CG2 3.57Å; L708-I886 HydrophobicContact CD1-CB 4.25Å; L708-I886 HydrophobicContact CD1-CG2 4.14Å; L708-M887 HydrophobicContact CD1-CB 3.77Å; L708-M887 HydrophobicContact CD1-CE 4.06Å; L708-I890 HydrophobicContact CD1-CD1 4.47Å
709L95.4Very high94.6Very high1 Ų124.4 Ų24.41%0.00512%0.124CC..Hα-helixtrans-62.7-39.3170.6-72.1177.1000111.5V586 H591 L593 N705 K706 F707 Q713 I886V586-L709 HydrophobicContact CG1-CD2 4.18Å; H591-L709 HydrophobicContact CB-CD1 4.03Å; L593-L709 HydrophobicContact CB-CB 3.97Å; L593-L709 HydrophobicContact CB-CD1 4.07Å; L593-L709 HydrophobicContact CD2-CB 4.11Å; N705-L709 WeakPolarHBondContact O-CG 3.39Å; N705-L709 PolarHBondContact O-N 2.89Å; K706-L709 PolarHBondContact O-N 3.42Å; F707-L709 PolarHBondContact O-N 3.04Å; L709-Q713 VanDerWaalsContact O-CB 3.28Å; L709-Q713 WeakPolarHBondContact O-CB 3.47Å; L709-Q713 PolarHBondContact O-N 3.32Å; L709-I886 HydrophobicContact CD2-CD1 3.81Å; L709-I886 HydrophobicContact CD2-CG1 4.35Å; L709-I886 HydrophobicContact CG-CD1 4.2Å; L709-I886 HydrophobicContact CG-CG1 4.27Å
710L94.9Very high93.9Very high1 Ų124.4 Ų24.41%0.00512%0.124CC..Hα-helixtrans-64.2-44.5175.6-177.161.3000111.4L593 T595 V646 L650 M702 K706 F707 L708 Q713 R714L593-L710 HydrophobicContact CD2-CB 3.63Å; L593-L710 HydrophobicContact CD2-CD1 4.12Å; L593-L710 HydrophobicContact CD2-CG 4.46Å; T595-L710 HydrophobicContact CG2-CD1 3.95Å; V646-L710 HydrophobicContact CG2-CD2 3.61Å; L650-L710 HydrophobicContact CD2-CD2 4.34Å; L650-L710 HydrophobicContact CD2-CG 3.93Å; M702-L710 HydrophobicContact CE-CD2 4.41Å; K706-L710 PolarHBondContact O-N 3.14Å; F707-L710 WeakPolarHBondContact O-CB 3.15Å; F707-L710 PolarHBondContact O-N 3.05Å; L708-L710 VanDerWaalsContact C-N 3.32Å; L710-Q713 PolarHBondContact O-N 3.5Å; L710-R714 HydrophobicContact CD1-CG 4.24Å; L710-R714 WeakPolarHBondContact O-CG 3.43Å; L710-R714 PolarHBondContact O-N 3.31Å
711V96.6Very high93.4Very high1 Ų124.7 Ų24.71%0.00612%0.124CC..Hα-helixtrans-59.8-54.2174.8174.70000110.6L650 F707 L708 Q713 R714 Y715 M743L650-V711 HydrophobicContact CD1-CG2 4.22Å; L650-V711 HydrophobicContact CD2-CG2 4.33Å; F707-V711 HydrophobicContact CD1-CG2 4.26Å; F707-V711 HydrophobicContact CE1-CG2 3.89Å; F707-V711 HydrophobicContact CZ-CG2 4.31Å; F707-V711 WeakPolarHBondContact O-CG2 3.22Å; F707-V711 PolarHBondContact O-N 3.12Å; L708-V711 PolarHBondContact O-N 2.89Å; V711-Q713 PolarHBondContact O-N 2.74Å; V711-R714 PolarHBondContact O-N 3.15Å; V711-Y715 HydrophobicContact CG1-CD2 3.78Å; V711-Y715 HydrophobicContact CG1-CE2 3.95Å; V711-Y715 WeakPolarHBondContact O-CD2 3.4Å; V711-Y715 PolarHBondContact O-N 2.64Å; V711-M743 HydrophobicContact CG1-CG 3.77Å; V711-M743 HydrophobicContact CG1-SD 4.18Å
712L94.8Very high92.6Very high5 Ų524.2 Ų24.23%0.02612%0.122CC..Hα-helixtrans-55.2-37177.4-79168.5000112.8L708 E716 L717 A718 F721 M743 I886 I890L708-L712 WeakPolarHBondContact O-CB 3.23Å; L708-L712 WeakPolarHBondContact O-CG 3.24Å; L708-L712 PolarHBondContact O-N 2.75Å; L712-E716 PolarHBondContact O-N 2.88Å; L712-L717 HydrophobicContact CD2-CB 4.19Å; L712-L717 PolarHBondContact O-N 3.32Å; L712-A718 HydrophobicContact CB-CB 4.44Å; L712-A718 PolarHBondContact O-N 2.92Å; L712-A718 VanDerWaalsContact O-N 3.08Å; L712-F721 HydrophobicContact CD2-CD2 3.74Å; L712-F721 HydrophobicContact CD2-CE2 3.98Å; L712-F721 HydrophobicContact CD2-CG 4.41Å; L712-M743 HydrophobicContact CD2-CE 4.1Å; L712-M743 HydrophobicContact CD2-SD 3.73Å; L712-M743 HydrophobicContact CG-SD 4.36Å; L712-I886 HydrophobicContact CD1-CG2 3.8Å; L712-I890 HydrophobicContact CD1-CD1 4.11Å; L712-I890 HydrophobicContact CD1-CG1 4.42Å; L712-I890 HydrophobicContact CD2-CD1 4.28Å; L712-I890 HydrophobicContact CD2-CG1 4.48Å; L712-I890 HydrophobicContact CG-CD1 4.31Å
713Q93Very high91.2Very high22 Ų2229 Ų2910%0.10314%0.143CC..Hα-helixtrans-73.6-43.2178.9-176.8171-9.100112.5V586 T595 L709 L710 V711 E716V586-Q713 HydrophobicContact CG2-CB 4.28Å; V586-Q713 VanDerWaalsContact CG2-CD 3.44Å; V586-Q713 HydrophobicContact CG2-CG 4Å; T595-Q713 VanDerWaalsContact CG2-CD 3.41Å; L709-Q713 VanDerWaalsContact O-CB 3.28Å; L709-Q713 WeakPolarHBondContact O-CB 3.47Å; L709-Q713 PolarHBondContact O-N 3.32Å; L710-Q713 PolarHBondContact O-N 3.5Å; V711-Q713 PolarHBondContact O-N 2.74Å; Q713-E716 WeakPolarHBondContact O-CA 3.41Å; Q713-E716 PolarHBondContact O-N 3.49Å
714R94.4Very high89.6Confident1 Ų132.2 Ų32.20%0.00417%0.165CC..Hα-helixtrans-71.2-33.5179.8-69.4-71.9173.4-98.6-15112.6T595 K596 Y598 E647 L650 V654 L710 V711 E716T595-R714 PolarHBondContact OG1-NH2 3.27Å; T595-R714 VanDerWaalsContact OG1-NH2 3.11Å; K596-R714 PolarHBondContact O-NH1 2.81Å; K596-R714 PolarHBondContact O-NH2 3Å; K596-R714 VanDerWaalsContact O-NH2 3.07Å; Y598-R714 PolarHBondContact O-NH1 3.27Å; E647-R714 IonicContact OE1-CZ 2.69Å; E647-R714 VanDerWaalsContact OE1-CZ 3.31Å; E647-R714 IonicContact OE1-NE 3.21Å; E647-R714 PolarHBondContact OE1-NE 3.45Å; E647-R714 VanDerWaalsContact OE1-NE 3.11Å; E647-R714 IonicContact OE1-NH2 2.64Å; E647-R714 PolarHBondContact OE1-NH2 3.42Å; E647-R714 IonicContact OE2-CZ 2.76Å; E647-R714 IonicContact OE2-NE 2.84Å; E647-R714 PolarHBondContact OE2-NE 3.12Å; E647-R714 IonicContact OE2-NH2 3.4Å; L650-R714 HydrophobicContact CD2-CB 3.89Å; L650-R714 HydrophobicContact CD2-CG 3.73Å; L650-R714 HydrophobicContact CG-CB 3.93Å; L650-R714 HydrophobicContact CG-CG 4.13Å; V654-R714 WeakPolarHBondContact CG1-O 3.5Å; V654-R714 HydrophobicContact CG2-CB 4.25Å; L710-R714 HydrophobicContact CD1-CG 4.24Å; L710-R714 WeakPolarHBondContact O-CG 3.43Å; L710-R714 PolarHBondContact O-N 3.31Å; V711-R714 PolarHBondContact O-N 3.15Å; R714-E716 PolarHBondContact O-N 3.42Å
715Y96.2Very high88Confident1 Ų132.7 Ų32.70%0.00417%0.166CC..THydrogen-bonded Turntrans-71-5168.1-85.3-96.9000113.7L650 V654 A657 V711 L717 E742 M743 V746L650-Y715 HydrophobicContact CD1-CE2 4.15Å; V654-Y715 HydrophobicContact CG2-CD1 4.25Å; V654-Y715 HydrophobicContact CG2-CD2 3.43Å; V654-Y715 VanDerWaalsContact CG2-CD2 3.43Å; V654-Y715 HydrophobicContact CG2-CE1 4.3Å; V654-Y715 HydrophobicContact CG2-CE2 3.48Å; V654-Y715 VanDerWaalsContact CG2-CE2 3.48Å; V654-Y715 HydrophobicContact CG2-CG 3.84Å; A657-Y715 HydrophobicContact CB-CD1 4.45Å; A657-Y715 HydrophobicContact CB-CE1 3.68Å; V711-Y715 HydrophobicContact CG1-CD2 3.78Å; V711-Y715 HydrophobicContact CG1-CE2 3.95Å; V711-Y715 WeakPolarHBondContact O-CD2 3.4Å; V711-Y715 PolarHBondContact O-N 2.64Å; Y715-L717 HydrophobicContact CD1-CD1 4.48Å; Y715-L717 HydrophobicContact CG-CD1 4.49Å; Y715-L717 PolarHBondContact O-N 2.87Å; Y715-E742 HydrophobicContact CE1-CB 4.34Å; Y715-M743 HydrophobicContact CD1-CB 3.75Å; Y715-M743 HydrophobicContact CD1-CG 4.31Å; Y715-M743 HydrophobicContact CD2-CB 4.33Å; Y715-M743 HydrophobicContact CD2-CG 4.03Å; Y715-M743 HydrophobicContact CE1-CB 3.72Å; Y715-M743 HydrophobicContact CE1-CG 4.42Å; Y715-M743 HydrophobicContact CE2-CB 4.32Å; Y715-M743 HydrophobicContact CE2-CG 4.17Å; Y715-M743 HydrophobicContact CG-CB 4.06Å; Y715-M743 HydrophobicContact CG-CG 4.11Å; Y715-V746 WeakPolarHBondContact OH-CG2 3.39Å
716E93.8Very high86.1Confident37 Ų3737.9 Ų37.917%0.17320%0.203CC..THydrogen-bonded Turntrans6325.1-178.1-49.9-177-133.700113.3R599 S601 Q658 L712 Q713 R714R599-E716 IonicContact CZ-OE2 2.68Å; R599-E716 IonicContact NE-OE2 3.32Å; R599-E716 PolarHBondContact NE-OE2 2.91Å; R599-E716 IonicContact NH2-OE2 2.66Å; R599-E716 PolarHBondContact NH2-OE2 3.37Å; S601-E716 WeakPolarHBondContact CB-OE1 3.49Å; S601-E716 PolarHBondContact N-OE1 3.42Å; S601-E716 PolarHBondContact OG-OE1 3.23Å; S601-E716 PolarHBondContact OG-OE2 2.87Å; Q658-E716 PolarHBondContact NE2-OE1 3.48Å; Q658-E716 VanDerWaalsContact NE2-OE1 3.15Å; L712-E716 PolarHBondContact O-N 2.88Å; Q713-E716 WeakPolarHBondContact O-CA 3.41Å; Q713-E716 PolarHBondContact O-N 3.49Å; R714-E716 PolarHBondContact O-N 3.42Å
717L93.1Very high84.8Confident0 Ų036 Ų360%020%0.198CC..  trans-100.5-7.1-176.7-68.4174.9000114.4L712 Y715 E719 A720 F721 Y736 L739 I740 M743L712-L717 HydrophobicContact CD2-CB 4.19Å; L712-L717 PolarHBondContact O-N 3.32Å; Y715-L717 HydrophobicContact CD1-CD1 4.48Å; Y715-L717 HydrophobicContact CG-CD1 4.49Å; Y715-L717 PolarHBondContact O-N 2.87Å; L717-E719 VanDerWaalsContact C-N 3.34Å; L717-E719 PolarHBondContact O-N 3.28Å; L717-A720 HydrophobicContact CD2-CB 4.1Å; L717-A720 WeakPolarHBondContact O-CA 3.49Å; L717-A720 VanDerWaalsContact O-CB 3.32Å; L717-A720 WeakPolarHBondContact O-CB 3.35Å; L717-A720 PolarHBondContact O-N 3.34Å; L717-F721 HydrophobicContact CB-CD2 4.31Å; L717-F721 HydrophobicContact CB-CE2 4.4Å; L717-F721 PolarHBondContact O-N 3.41Å; L717-Y736 HydrophobicContact CD2-CD1 3.84Å; L717-L739 HydrophobicContact CD1-CB 4.3Å; L717-L739 HydrophobicContact CD2-CB 4.23Å; L717-L739 HydrophobicContact CG-CB 4.5Å; L717-I740 HydrophobicContact CD1-CB 4.47Å; L717-I740 HydrophobicContact CD1-CG1 3.75Å; L717-I740 HydrophobicContact CD2-CD1 4.4Å; L717-I740 HydrophobicContact CD2-CG1 3.79Å; L717-I740 HydrophobicContact CG-CG1 4.4Å; L717-M743 HydrophobicContact CD1-CB 4.22Å; L717-M743 HydrophobicContact CD1-CE 4.33Å; L717-M743 HydrophobicContact CD1-SD 3.8Å
718A88.8Confident83.7Confident14 Ų1445.3 Ų45.312%0.11624%0.239CC..Hα-helixtrans-56.3-43.1-177.600000113.3V586 L712 N722V586-A718 HydrophobicContact CG1-CB 3.95Å; L712-A718 HydrophobicContact CB-CB 4.44Å; L712-A718 PolarHBondContact O-N 2.92Å; L712-A718 VanDerWaalsContact O-N 3.08Å; A718-N722 WeakPolarHBondContact O-CB 3.35Å; A718-N722 PolarHBondContact O-N 3.28Å; A718-N722 VanDerWaalsContact O-N 3.15Å
719E83.3Confident83.1Confident122 Ų12249 Ų4957%0.5726%0.259SS*.Hα-helixtrans-69.7-36173.4-64.1-140.7114.500112.4L717 F721 N722 K723L717-E719 VanDerWaalsContact C-N 3.34Å; L717-E719 PolarHBondContact O-N 3.28Å; E719-F721 VanDerWaalsContact C-N 3.25Å; E719-F721 PolarHBondContact O-N 2.91Å; E719-N722 PolarHBondContact O-N 3.2Å; E719-K723 PolarHBondContact O-N 3Å; E719-K723 IonicContact OE1-NZ 3.69Å; E719-K723 PolarHBondContact OE1-NZ 3.22Å
720A83.9Confident82.5Confident3 Ų354.4 Ų54.43%0.02528%0.284CS..Hα-helixtrans-63.6-28.7-178.700000112.7L717 I725 Y736 R897L717-A720 HydrophobicContact CD2-CB 4.1Å; L717-A720 WeakPolarHBondContact O-CA 3.49Å; L717-A720 VanDerWaalsContact O-CB 3.32Å; L717-A720 WeakPolarHBondContact O-CB 3.35Å; L717-A720 PolarHBondContact O-N 3.34Å; A720-I725 HydrophobicContact CB-CD1 3.58Å; A720-I725 HydrophobicContact CB-CG1 4.48Å; A720-Y736 HydrophobicContact CB-CD1 4.29Å; A720-Y736 HydrophobicContact CB-CE1 4.34Å; A720-R897 PolarHBondContact O-NH2 3.39Å
721F86.2Confident82.1Confident8 Ų859.7 Ų59.74%0.03531%0.312CS..Hα-helixtrans-85.5-47.1169.8-80.1-95.5000112.4L712 L717 E719 K723 I740 M743 Y889 I890 T893 V894L712-F721 HydrophobicContact CD2-CD2 3.74Å; L712-F721 HydrophobicContact CD2-CE2 3.98Å; L712-F721 HydrophobicContact CD2-CG 4.41Å; L717-F721 HydrophobicContact CB-CD2 4.31Å; L717-F721 HydrophobicContact CB-CE2 4.4Å; L717-F721 PolarHBondContact O-N 3.41Å; E719-F721 VanDerWaalsContact C-N 3.25Å; E719-F721 PolarHBondContact O-N 2.91Å; F721-K723 PolarHBondContact O-N 3.06Å; F721-I740 HydrophobicContact CE2-CD1 4.31Å; F721-I740 HydrophobicContact CE2-CG1 4.09Å; F721-I740 HydrophobicContact CZ-CG1 4.43Å; F721-I740 HydrophobicContact CZ-CG2 4.34Å; F721-M743 HydrophobicContact CE2-CE 4.29Å; F721-M743 HydrophobicContact CZ-CE 4.4Å; F721-Y889 VanDerWaalsContact C-OH 3.24Å; F721-Y889 HydrophobicContact CB-CE1 4.03Å; F721-Y889 PolarHBondContact O-OH 3.22Å; F721-I890 HydrophobicContact CD1-CG1 4.44Å; F721-I890 HydrophobicContact CE1-CB 4.22Å; F721-I890 HydrophobicContact CE1-CG1 4.22Å; F721-I890 HydrophobicContact CE1-CG2 3.97Å; F721-I890 HydrophobicContact CZ-CG2 4.07Å; F721-T893 HydrophobicContact CD1-CG2 3.61Å; F721-T893 HydrophobicContact CE1-CG2 3.95Å; F721-V894 HydrophobicContact CE1-CG2 4.27Å; F721-V894 HydrophobicContact CZ-CG2 4.36Å
722N76.4Confident81.7Confident71 Ų7162.1 Ų62.138%0.3833%0.325SS..Hα-helixtrans-70.2-21.9-172.2-80.6-14.7000115.5Q587 S588 A718 E719Q587-N722 PolarHBondContact O-ND2 3.49Å; S588-N722 WeakPolarHBondContact CB-OD1 3.41Å; S588-N722 PolarHBondContact OG-OD1 3.47Å; A718-N722 WeakPolarHBondContact O-CB 3.35Å; A718-N722 PolarHBondContact O-N 3.28Å; A718-N722 VanDerWaalsContact O-N 3.15Å; E719-N722 PolarHBondContact O-N 3.2Å
723K65.8Low81.3Confident125 Ų12562.5 Ų62.554%0.54333%0.327SS..SBendtrans-127.5146.3-177.7-65.1171.9-178.21670111.1E719 F721 I725E719-K723 PolarHBondContact O-N 3Å; E719-K723 IonicContact OE1-NZ 3.69Å; E719-K723 PolarHBondContact OE1-NZ 3.22Å; F721-K723 PolarHBondContact O-N 3.06Å; K723-I725 PolarHBondContact O-N 3.41Å; K723-I725 VanDerWaalsContact O-N 3.08Å
724T62.3Low81.3Confident139 Ų13966.4 Ų66.485%0.85334%0.343SS*.  trans-65.2108.8167.6-45.70000109.4S726T724-S726 PolarHBondContact O-N 3.11Å
725I62.3Low81.2Confident36 Ų3668.7 Ų68.719%0.18535%0.354CS..  trans-72.690.8-178.1-45.7175.1000109.8A720 K723 T727 Y736 L905A720-I725 HydrophobicContact CB-CD1 3.58Å; A720-I725 HydrophobicContact CB-CG1 4.48Å; K723-I725 PolarHBondContact O-N 3.41Å; K723-I725 VanDerWaalsContact O-N 3.08Å; I725-T727 HydrophobicContact CG2-CG2 3.79Å; I725-T727 PolarHBondContact O-N 3.31Å; I725-Y736 HydrophobicContact CD1-CD2 4.17Å; I725-Y736 HydrophobicContact CD1-CE2 4.29Å; I725-Y736 HydrophobicContact CG2-CE2 4.46Å; I725-L905 HydrophobicContact CB-CD1 4.25Å; I725-L905 HydrophobicContact CD1-CD2 4.25Å
726S58.1Low81Confident120 Ų12071.3 Ų71.384%0.83937%0.365SS*.  trans-82.152.3174.3179.80000112.1T724T724-S726 PolarHBondContact O-N 3.11Å
727T68Low81Confident46 Ų4670.2 Ų70.228%0.28236%0.36SS..  trans-93.3147.5170.2-166.40000111.3I725 D729 L732 I733I725-T727 HydrophobicContact CG2-CG2 3.79Å; I725-T727 PolarHBondContact O-N 3.31Å; T727-D729 PolarHBondContact OG1-N 2.97Å; T727-L732 HydrophobicContact CG2-CD2 4.4Å; T727-I733 HydrophobicContact CG2-CD1 4.04Å; T727-I733 HydrophobicContact CG2-CG1 3.74Å
728K72.9Confident81.2Confident198 Ų19871.5 Ų71.586%0.86137%0.367SS*.  trans-101.7-1.5170-65.9-172.6177.9-176.10112.7Q730K728-Q730 PolarHBondContact O-N 3.42Å
729D84.1Confident81.6Confident78 Ų7871.1 Ų71.142%0.41736%0.363SS..  trans-74.9109.9178.8-174.4-21.9000110.2T727 D731 L732 I733T727-D729 PolarHBondContact OG1-N 2.97Å; D729-D731 PolarHBondContact OD1-N 3Å; D729-L732 HydrophobicContact CB-CB 3.86Å; D729-L732 PolarHBondContact OD1-N 3.02Å; D729-I733 WeakPolarHBondContact O-CD1 3.22Å; D729-I733 VanDerWaalsContact O-CG1 3.28Å; D729-I733 WeakPolarHBondContact O-CG1 3.44Å; D729-I733 PolarHBondContact O-N 3.4Å; D729-I733 VanDerWaalsContact O-N 3.09Å
730Q84.7Confident82.2Confident114 Ų11465.4 Ų65.453%0.53334%0.337SS..Hα-helixtrans-72.4-32.1-178.4-67.8-67.3-30.200112.6K728 I733 K734K728-Q730 PolarHBondContact O-N 3.42Å; Q730-I733 PolarHBondContact O-N 3.33Å; Q730-K734 WeakPolarHBondContact O-CB 3.45Å; Q730-K734 PolarHBondContact O-N 2.98Å
731D85.5Confident82.9Confident113 Ų11367.2 Ų67.260%0.60435%0.345SS*.Hα-helixtrans-71.7-38.4178.1-75-33.3000110.3D729 K734 Q735D729-D731 PolarHBondContact OD1-N 3Å; D731-K734 PolarHBondContact O-N 2.91Å; D731-Q735 VanDerWaalsContact O-CG 3.32Å; D731-Q735 WeakPolarHBondContact O-CG 3.36Å; D731-Q735 PolarHBondContact O-N 2.75Å
732L87.2Confident83.4Confident51 Ų5167.7 Ų67.727%0.26735%0.347SS..Hα-helixtrans-66.8-39.7173.5-174.963.6000112.1T727 D729 Q735 Y736T727-L732 HydrophobicContact CG2-CD2 4.4Å; D729-L732 HydrophobicContact CB-CB 3.86Å; D729-L732 PolarHBondContact OD1-N 3.02Å; L732-Q735 PolarHBondContact O-N 2.88Å; L732-Y736 HydrophobicContact CD1-CD2 4.29Å; L732-Y736 HydrophobicContact CD1-CE2 3.79Å; L732-Y736 HydrophobicContact CD2-CE2 3.91Å; L732-Y736 HydrophobicContact CG-CD2 3.95Å; L732-Y736 HydrophobicContact CG-CE2 3.53Å; L732-Y736 VanDerWaalsContact O-CD2 3.26Å; L732-Y736 WeakPolarHBondContact O-CD2 3.29Å; L732-Y736 PolarHBondContact O-N 2.61Å
733I88.1Confident84.4Confident13 Ų1364.4 Ų64.47%0.06733%0.329CS..Hα-helixtrans-61.3-45.3172.8-72.2164.3000110.5T727 D729 Q730 Q735 Y736 N737 N904 L905T727-I733 HydrophobicContact CG2-CD1 4.04Å; T727-I733 HydrophobicContact CG2-CG1 3.74Å; D729-I733 WeakPolarHBondContact O-CD1 3.22Å; D729-I733 VanDerWaalsContact O-CG1 3.28Å; D729-I733 WeakPolarHBondContact O-CG1 3.44Å; D729-I733 PolarHBondContact O-N 3.4Å; D729-I733 VanDerWaalsContact O-N 3.09Å; Q730-I733 PolarHBondContact O-N 3.33Å; I733-Q735 VanDerWaalsContact C-N 3.34Å; I733-Q735 PolarHBondContact O-N 3.13Å; I733-Y736 PolarHBondContact O-N 2.82Å; I733-N737 WeakPolarHBondContact O-CB 3.36Å; I733-N737 VanDerWaalsContact O-CG 3.23Å; I733-N737 PolarHBondContact O-N 3.36Å; I733-N737 PolarHBondContact O-OD1 3.09Å; I733-N904 HydrophobicContact CG2-CB 4.13Å; I733-N904 VanDerWaalsContact CG2-O 3.29Å; I733-N904 WeakPolarHBondContact CG2-O 3.24Å; I733-L905 HydrophobicContact CG1-CD2 4.17Å; I733-L905 HydrophobicContact CG2-CD2 4.29Å
734K91.6Very high86Confident104 Ų10458.4 Ų58.445%0.45230%0.304SS..Hα-helixtrans-58.7-45.3175.8-171.7-167.9177.1-165.90111.5E662 Q730 D731 N737 T738E662-K734 IonicContact OE2-NZ 2.57Å; E662-K734 PolarHBondContact OE2-NZ 3.11Å; Q730-K734 WeakPolarHBondContact O-CB 3.45Å; Q730-K734 PolarHBondContact O-N 2.98Å; D731-K734 PolarHBondContact O-N 2.91Å; K734-N737 PolarHBondContact O-N 3.37Å; K734-T738 PolarHBondContact O-N 3.41Å; K734-T738 PolarHBondContact O-OG1 2.9Å; K734-T738 VanDerWaalsContact O-OG1 3.07Å
735Q93.1Very high87.6Confident50 Ų5053 Ų5323%0.23427%0.269CS..Hα-helixtrans-59.8-50.8176.5-75.2166.931.600111.9A661 M663 D731 L732 I733 N737 T738 L739A661-Q735 WeakPolarHBondContact O-CG 3.4Å; M663-Q735 HydrophobicContact CG-CG 4.05Å; D731-Q735 VanDerWaalsContact O-CG 3.32Å; D731-Q735 WeakPolarHBondContact O-CG 3.36Å; D731-Q735 PolarHBondContact O-N 2.75Å; L732-Q735 PolarHBondContact O-N 2.88Å; I733-Q735 VanDerWaalsContact C-N 3.34Å; I733-Q735 PolarHBondContact O-N 3.13Å; Q735-N737 VanDerWaalsContact C-N 3.29Å; Q735-N737 PolarHBondContact O-N 2.68Å; Q735-T738 PolarHBondContact O-N 3.05Å; Q735-L739 VanDerWaalsContact O-CG 3.32Å; Q735-L739 WeakPolarHBondContact O-CG 3.3Å; Q735-L739 PolarHBondContact O-N 2.92Å
736Y92.3Very high89.3Confident56 Ų5651.8 Ų51.822%0.2226%0.263CS..Hα-helixtrans-58.4-42.3176-75.5-49.6000112.2L717 A720 I725 L732 I733 L739 I740L717-Y736 HydrophobicContact CD2-CD1 3.84Å; A720-Y736 HydrophobicContact CB-CD1 4.29Å; A720-Y736 HydrophobicContact CB-CE1 4.34Å; I725-Y736 HydrophobicContact CD1-CD2 4.17Å; I725-Y736 HydrophobicContact CD1-CE2 4.29Å; I725-Y736 HydrophobicContact CG2-CE2 4.46Å; L732-Y736 HydrophobicContact CD1-CD2 4.29Å; L732-Y736 HydrophobicContact CD1-CE2 3.79Å; L732-Y736 HydrophobicContact CD2-CE2 3.91Å; L732-Y736 HydrophobicContact CG-CD2 3.95Å; L732-Y736 HydrophobicContact CG-CE2 3.53Å; L732-Y736 VanDerWaalsContact O-CD2 3.26Å; L732-Y736 WeakPolarHBondContact O-CD2 3.29Å; L732-Y736 PolarHBondContact O-N 2.61Å; I733-Y736 PolarHBondContact O-N 2.82Å; Y736-L739 PolarHBondContact O-N 3.11Å; Y736-I740 VanDerWaalsContact O-CG1 3.25Å; Y736-I740 WeakPolarHBondContact O-CG1 3.47Å; Y736-I740 PolarHBondContact O-N 3.15Å
737N94.1Very high91.3Very high14 Ų1446.2 Ų46.28%0.07522%0.224CC..Hα-helixtrans-62.4-47.5179.3-73.4-6.2000111.1I733 K734 Q735 L739 I740 E741 N904 T907 M910I733-N737 WeakPolarHBondContact O-CB 3.36Å; I733-N737 VanDerWaalsContact O-CG 3.23Å; I733-N737 PolarHBondContact O-N 3.36Å; I733-N737 PolarHBondContact O-OD1 3.09Å; K734-N737 PolarHBondContact O-N 3.37Å; Q735-N737 VanDerWaalsContact C-N 3.29Å; Q735-N737 PolarHBondContact O-N 2.68Å; N737-L739 PolarHBondContact O-N 3Å; N737-I740 PolarHBondContact O-N 3.06Å; N737-E741 PolarHBondContact O-N 3.07Å; N737-E741 VanDerWaalsContact O-N 3.11Å; N737-N904 PolarHBondContact ND2-O 3.08Å; N737-T907 HydrophobicContact CB-CG2 4.03Å; N737-M910 HydrophobicContact CB-CE 3.44Å; N737-M910 VanDerWaalsContact CB-CE 3.44Å; N737-M910 WeakPolarHBondContact O-CE 3.35Å; N737-M910 WeakPolarHBondContact OD1-CE 3.14Å
738T96.3Very high92.7Very high26 Ų2644.1 Ų44.116%0.1621%0.211CC..Hα-helixtrans-61.9-41.4176.1-53.90000112.2V660 A661 K734 Q735 I740 E741 E742V660-T738 HydrophobicContact CG1-CG2 3.75Å; A661-T738 HydrophobicContact CB-CG2 3.92Å; K734-T738 PolarHBondContact O-N 3.41Å; K734-T738 PolarHBondContact O-OG1 2.9Å; K734-T738 VanDerWaalsContact O-OG1 3.07Å; Q735-T738 PolarHBondContact O-N 3.05Å; T738-I740 VanDerWaalsContact C-N 3.34Å; T738-I740 PolarHBondContact O-N 3.46Å; T738-E741 PolarHBondContact O-N 2.97Å; T738-E742 HydrophobicContact CG2-CG 4.44Å; T738-E742 WeakPolarHBondContact O-CG 3.47Å; T738-E742 PolarHBondContact O-N 3.13Å
739L97.2Very high93.9Very high6 Ų635 Ų353%0.03117%0.171CC..Hα-helixtrans-64.9-34.7177.2-69.6174.1000113.2A657 Q658 A661 M663 L717 Q735 Y736 N737 M743A657-L739 HydrophobicContact CB-CD2 4.1Å; Q658-L739 HydrophobicContact CG-CD2 3.84Å; A661-L739 HydrophobicContact CB-CD2 4.01Å; A661-L739 HydrophobicContact CB-CG 4.04Å; M663-L739 HydrophobicContact SD-CD1 3.99Å; M663-L739 HydrophobicContact SD-CD2 4.47Å; L717-L739 HydrophobicContact CD1-CB 4.3Å; L717-L739 HydrophobicContact CD2-CB 4.23Å; L717-L739 HydrophobicContact CG-CB 4.5Å; Q735-L739 VanDerWaalsContact O-CG 3.32Å; Q735-L739 WeakPolarHBondContact O-CG 3.3Å; Q735-L739 PolarHBondContact O-N 2.92Å; Y736-L739 PolarHBondContact O-N 3.11Å; N737-L739 PolarHBondContact O-N 3Å; L739-M743 VanDerWaalsContact O-CB 3.27Å; L739-M743 WeakPolarHBondContact O-CB 3.22Å; L739-M743 PolarHBondContact O-N 2.58Å
740I96.8Very high94.5Very high2 Ų231.3 Ų31.31%0.0115%0.151CC..Hα-helixtrans-67.1-42.1174.8-67.3163.1000110.5L717 F721 Y736 N737 T738 M743 L744 M910L717-I740 HydrophobicContact CD1-CB 4.47Å; L717-I740 HydrophobicContact CD1-CG1 3.75Å; L717-I740 HydrophobicContact CD2-CD1 4.4Å; L717-I740 HydrophobicContact CD2-CG1 3.79Å; L717-I740 HydrophobicContact CG-CG1 4.4Å; F721-I740 HydrophobicContact CE2-CD1 4.31Å; F721-I740 HydrophobicContact CE2-CG1 4.09Å; F721-I740 HydrophobicContact CZ-CG1 4.43Å; F721-I740 HydrophobicContact CZ-CG2 4.34Å; Y736-I740 VanDerWaalsContact O-CG1 3.25Å; Y736-I740 WeakPolarHBondContact O-CG1 3.47Å; Y736-I740 PolarHBondContact O-N 3.15Å; N737-I740 PolarHBondContact O-N 3.06Å; T738-I740 VanDerWaalsContact C-N 3.34Å; T738-I740 PolarHBondContact O-N 3.46Å; I740-M743 PolarHBondContact O-N 2.78Å; I740-L744 HydrophobicContact CG2-CD1 3.88Å; I740-L744 HydrophobicContact CG2-CG 4.31Å; I740-L744 WeakPolarHBondContact O-CB 3.49Å; I740-L744 VanDerWaalsContact O-CG 3.24Å; I740-L744 WeakPolarHBondContact O-CG 3.04Å; I740-L744 PolarHBondContact O-N 3.24Å; I740-M910 HydrophobicContact CB-CE 4.07Å; I740-M910 HydrophobicContact CB-SD 4.2Å; I740-M910 HydrophobicContact CD1-CE 4.34Å; I740-M910 HydrophobicContact CG2-CE 4.25Å; I740-M910 HydrophobicContact CG2-CG 3.95Å; I740-M910 HydrophobicContact CG2-SD 3.7Å
741E97.2Very high95.1Very high41 Ų4125.9 Ų25.919%0.19213%0.126CC..Hα-helixtrans-58.7-54.5174.1-70.3176.8-144.800111.2N737 T738 M743 L744 Q745 T907 M910 M913N737-E741 PolarHBondContact O-N 3.07Å; N737-E741 VanDerWaalsContact O-N 3.11Å; T738-E741 PolarHBondContact O-N 2.97Å; E741-M743 VanDerWaalsContact C-N 3.27Å; E741-M743 PolarHBondContact O-N 2.9Å; E741-L744 PolarHBondContact O-N 3.4Å; E741-L744 VanDerWaalsContact O-N 3.17Å; E741-Q745 WeakPolarHBondContact O-CB 3.16Å; E741-Q745 PolarHBondContact O-N 3.46Å; E741-T907 WeakPolarHBondContact OE1-CB 3.43Å; E741-T907 WeakPolarHBondContact OE1-CG2 3.43Å; E741-T907 PolarHBondContact OE1-OG1 2.98Å; E741-M910 HydrophobicContact CG-CB 4.49Å; E741-M910 HydrophobicContact CG-CG 3.6Å; E741-M913 HydrophobicContact CB-CE 4.29Å; E741-M913 HydrophobicContact CB-SD 4.15Å
742E97.3Very high95.6Very high19 Ų1920.9 Ų20.99%0.08910%0.1CC..Hα-helixtrans-61.6-34.4-179.5-60.8-68.2127.100112.5A657 V660 Y715 T738 V746 K840A657-E742 HydrophobicContact CB-CB 3.5Å; A657-E742 HydrophobicContact CB-CG 3.88Å; V660-E742 HydrophobicContact CG1-CG 4.1Å; V660-E742 WeakPolarHBondContact CG1-OE1 3.41Å; Y715-E742 HydrophobicContact CE1-CB 4.34Å; T738-E742 HydrophobicContact CG2-CG 4.44Å; T738-E742 WeakPolarHBondContact O-CG 3.47Å; T738-E742 PolarHBondContact O-N 3.13Å; E742-V746 WeakPolarHBondContact O-CG2 3.14Å; E742-V746 PolarHBondContact O-N 3.17Å; E742-K840 IonicContact OE1-NZ 3.33Å; E742-K840 PolarHBondContact OE1-NZ 3.37Å
743M98Very high95.9Very high1 Ų118.8 Ų18.81%0.0059%0.089CC..Hα-helixtrans-65.8-49.7173.6-174.3-165.768.400111.6V711 L712 Y715 L717 F721 L739 I740 E741 Q745 V746 L747 I890V711-M743 HydrophobicContact CG1-CG 3.77Å; V711-M743 HydrophobicContact CG1-SD 4.18Å; L712-M743 HydrophobicContact CD2-CE 4.1Å; L712-M743 HydrophobicContact CD2-SD 3.73Å; L712-M743 HydrophobicContact CG-SD 4.36Å; Y715-M743 HydrophobicContact CD1-CB 3.75Å; Y715-M743 HydrophobicContact CD1-CG 4.31Å; Y715-M743 HydrophobicContact CD2-CB 4.33Å; Y715-M743 HydrophobicContact CD2-CG 4.03Å; Y715-M743 HydrophobicContact CE1-CB 3.72Å; Y715-M743 HydrophobicContact CE1-CG 4.42Å; Y715-M743 HydrophobicContact CE2-CB 4.32Å; Y715-M743 HydrophobicContact CE2-CG 4.17Å; Y715-M743 HydrophobicContact CG-CB 4.06Å; Y715-M743 HydrophobicContact CG-CG 4.11Å; L717-M743 HydrophobicContact CD1-CB 4.22Å; L717-M743 HydrophobicContact CD1-CE 4.33Å; L717-M743 HydrophobicContact CD1-SD 3.8Å; F721-M743 HydrophobicContact CE2-CE 4.29Å; F721-M743 HydrophobicContact CZ-CE 4.4Å; L739-M743 VanDerWaalsContact O-CB 3.27Å; L739-M743 WeakPolarHBondContact O-CB 3.22Å; L739-M743 PolarHBondContact O-N 2.58Å; I740-M743 PolarHBondContact O-N 2.78Å; E741-M743 VanDerWaalsContact C-N 3.27Å; E741-M743 PolarHBondContact O-N 2.9Å; M743-Q745 PolarHBondContact O-N 2.97Å; M743-V746 PolarHBondContact O-N 2.96Å; M743-L747 WeakPolarHBondContact O-CG 3.29Å; M743-L747 PolarHBondContact O-N 2.84Å; M743-I890 HydrophobicContact CE-CD1 4.49Å; M743-I890 HydrophobicContact CE-CG2 4.4Å
744L98.3Very high96.2Very high0 Ų018.3 Ų18.30%09%0.087CC..Hα-helixtrans-61.2-37.4178.3-69.9170.6000111.1I740 E741 L747 I748 I890 M910 M913 I917I740-L744 HydrophobicContact CG2-CD1 3.88Å; I740-L744 HydrophobicContact CG2-CG 4.31Å; I740-L744 WeakPolarHBondContact O-CB 3.49Å; I740-L744 VanDerWaalsContact O-CG 3.24Å; I740-L744 WeakPolarHBondContact O-CG 3.04Å; I740-L744 PolarHBondContact O-N 3.24Å; E741-L744 PolarHBondContact O-N 3.4Å; E741-L744 VanDerWaalsContact O-N 3.17Å; L744-L747 PolarHBondContact O-N 2.78Å; L744-I748 WeakPolarHBondContact O-CG1 3.32Å; L744-I748 PolarHBondContact O-N 2.93Å; L744-I890 HydrophobicContact CD2-CG2 3.93Å; L744-M910 HydrophobicContact CD1-CB 4.2Å; L744-M910 HydrophobicContact CD1-CG 4.45Å; L744-M913 HydrophobicContact CB-CB 3.94Å; L744-M913 HydrophobicContact CB-SD 4.04Å; L744-M913 HydrophobicContact CD1-CB 4.36Å; L744-I917 HydrophobicContact CB-CD1 4.45Å; L744-I917 HydrophobicContact CD2-CD1 3.87Å
745Q97.5Very high96.4Very high26 Ų2615 Ų1512%0.1217%0.072CC..Hα-helixtrans-62.5-45.5175.3-171166.924.700112.2E741 M743 L747 I748 Y749 M913E741-Q745 WeakPolarHBondContact O-CB 3.16Å; E741-Q745 PolarHBondContact O-N 3.46Å; M743-Q745 PolarHBondContact O-N 2.97Å; Q745-L747 VanDerWaalsContact C-N 3.31Å; Q745-L747 PolarHBondContact O-N 3.26Å; Q745-I748 WeakPolarHBondContact O-CB 3.35Å; Q745-I748 PolarHBondContact O-N 2.82Å; Q745-Y749 HydrophobicContact CG-CD2 4.41Å; Q745-Y749 HydrophobicContact CG-CE1 3.98Å; Q745-Y749 HydrophobicContact CG-CE2 3.62Å; Q745-Y749 WeakPolarHBondContact CG-OH 3.3Å; Q745-Y749 PolarHBondContact NE2-OH 3.02Å; Q745-Y749 WeakPolarHBondContact O-CD1 3.38Å; Q745-Y749 VanDerWaalsContact O-CG 3.27Å; Q745-Y749 PolarHBondContact O-N 3.2Å; Q745-M913 HydrophobicContact CB-CE 3.89Å; Q745-M913 HydrophobicContact CB-SD 4.04Å; Q745-M913 HydrophobicContact CG-CE 4.27Å
746V97.9Very high96.6Very high10 Ų1014 Ų146%0.0617%0.069CC..Hα-helixtrans-63-36.3173.8167.60000112L653 L695 Y715 E742 M743 Y749 I750L653-V746 HydrophobicContact CD1-CG1 4.45Å; L695-V746 HydrophobicContact CD1-CG1 4.13Å; Y715-V746 WeakPolarHBondContact OH-CG2 3.39Å; E742-V746 WeakPolarHBondContact O-CG2 3.14Å; E742-V746 PolarHBondContact O-N 3.17Å; M743-V746 PolarHBondContact O-N 2.96Å; V746-Y749 PolarHBondContact O-N 3.3Å; V746-I750 HydrophobicContact CG1-CD1 3.79Å; V746-I750 HydrophobicContact CG1-CG1 4.33Å; V746-I750 VanDerWaalsContact O-CG1 3.3Å; V746-I750 WeakPolarHBondContact O-CG1 3.43Å; V746-I750 PolarHBondContact O-N 3.2Å
747L98.4Very high96.7Very high3 Ų312.9 Ų12.92%0.0167%0.068CC..Hα-helixtrans-65.9-36.7174.1-64.8177.8000112.7L708 M743 L744 Q745 Y749 I750 V751 M887 I917L708-L747 HydrophobicContact CD2-CD1 4.19Å; L708-L747 HydrophobicContact CD2-CD2 3.41Å; L708-L747 VanDerWaalsContact CD2-CD2 3.41Å; L708-L747 HydrophobicContact CD2-CG 4.47Å; M743-L747 WeakPolarHBondContact O-CG 3.29Å; M743-L747 PolarHBondContact O-N 2.84Å; L744-L747 PolarHBondContact O-N 2.78Å; Q745-L747 VanDerWaalsContact C-N 3.31Å; Q745-L747 PolarHBondContact O-N 3.26Å; L747-Y749 VanDerWaalsContact C-N 3.35Å; L747-I750 HydrophobicContact CD2-CD1 4.44Å; L747-V751 PolarHBondContact O-N 3.08Å; L747-M887 HydrophobicContact CD1-CE 4.12Å; L747-I917 HydrophobicContact CB-CD1 4.43Å
748I98.1Very high96.8Very high2 Ų212.4 Ų12.41%0.017%0.067CC..Hα-helixtrans-61.2-44.9171-68.9166.4000110.1L744 Q745 V751 G752 Y834 M913 H916 I917 L920L744-I748 WeakPolarHBondContact O-CG1 3.32Å; L744-I748 PolarHBondContact O-N 2.93Å; Q745-I748 WeakPolarHBondContact O-CB 3.35Å; Q745-I748 PolarHBondContact O-N 2.82Å; I748-V751 PolarHBondContact O-N 3.25Å; I748-G752 WeakPolarHBondContact O-CA 3.23Å; I748-G752 PolarHBondContact O-N 3.16Å; I748-Y834 HydrophobicContact CD1-CD2 3.78Å; I748-Y834 HydrophobicContact CD1-CE2 4.01Å; I748-Y834 HydrophobicContact CD1-CG 4.13Å; I748-Y834 HydrophobicContact CG2-CD2 4.47Å; I748-Y834 HydrophobicContact CG2-CG 4.42Å; I748-M913 HydrophobicContact CD1-CB 3.82Å; I748-M913 HydrophobicContact CD1-CG 4.02Å; I748-H916 HydrophobicContact CD1-CB 4.17Å; I748-I917 HydrophobicContact CD1-CG1 4.22Å; I748-I917 HydrophobicContact CG1-CD1 4.09Å; I748-I917 HydrophobicContact CG1-CG1 3.54Å; I748-L920 HydrophobicContact CG2-CD1 4.48Å
749Y97.8Very high96.8Very high6 Ų611.1 Ų11.12%0.0246%0.059CC..Hα-helixtrans-66-46-178.7-59.1-20.9000112.7Y688 I692 Q745 V746 L747 V751 E753 Y834Y688-Y749 WeakPolarHBondContact OH-CD2 3.38Å; Y688-Y749 WeakPolarHBondContact OH-CE2 3.23Å; I692-Y749 HydrophobicContact CD1-CD2 4.41Å; Q745-Y749 HydrophobicContact CG-CD2 4.41Å; Q745-Y749 HydrophobicContact CG-CE1 3.98Å; Q745-Y749 HydrophobicContact CG-CE2 3.62Å; Q745-Y749 WeakPolarHBondContact CG-OH 3.3Å; Q745-Y749 PolarHBondContact NE2-OH 3.02Å; Q745-Y749 WeakPolarHBondContact O-CD1 3.38Å; Q745-Y749 VanDerWaalsContact O-CG 3.27Å; Q745-Y749 PolarHBondContact O-N 3.2Å; V746-Y749 PolarHBondContact O-N 3.3Å; L747-Y749 VanDerWaalsContact C-N 3.35Å; Y749-V751 PolarHBondContact O-N 3.42Å; Y749-E753 HydrophobicContact CD1-CG 4.37Å; Y749-E753 WeakPolarHBondContact O-CB 3.48Å; Y749-E753 PolarHBondContact O-N 2.97Å; Y749-Y834 WeakPolarHBondContact CE1-O 3.37Å
750I98.2Very high96.8Very high0 Ų010.9 Ų10.90%06%0.058CC..Hα-helixtrans-54.9-41.9177.6-69.5163.7000111.1L695 Q696 A699 F707 V746 L747 V878 L881L695-I750 HydrophobicContact CB-CD1 3.85Å; L695-I750 HydrophobicContact CB-CG1 3.97Å; L695-I750 HydrophobicContact CD1-CD1 3.89Å; Q696-I750 HydrophobicContact CG-CB 4.45Å; Q696-I750 HydrophobicContact CG-CG2 4.04Å; Q696-I750 WeakPolarHBondContact CG-O 3.31Å; Q696-I750 PolarHBondContact NE2-O 3.22Å; A699-I750 HydrophobicContact CB-CG2 4.09Å; F707-I750 HydrophobicContact CE1-CD1 4.15Å; F707-I750 HydrophobicContact CZ-CD1 4.16Å; V746-I750 HydrophobicContact CG1-CD1 3.79Å; V746-I750 HydrophobicContact CG1-CG1 4.33Å; V746-I750 VanDerWaalsContact O-CG1 3.3Å; V746-I750 WeakPolarHBondContact O-CG1 3.43Å; V746-I750 PolarHBondContact O-N 3.2Å; L747-I750 HydrophobicContact CD2-CD1 4.44Å; I750-V878 HydrophobicContact CG2-CG1 3.92Å; I750-V878 WeakPolarHBondContact O-CG1 3.39Å; I750-L881 HydrophobicContact CG2-CD1 3.72Å
751V96.8Very high96.7Very high1 Ų116.4 Ų16.41%0.0069%0.087CC..Hα-helixtrans-92.2-32-174.5-176.70000113.8L747 I748 Y749 R754 V878 L881 L882L747-V751 PolarHBondContact O-N 3.08Å; I748-V751 PolarHBondContact O-N 3.25Å; Y749-V751 PolarHBondContact O-N 3.42Å; V751-R754 PolarHBondContact O-NE 2.86Å; V751-R754 PolarHBondContact O-NH2 2.73Å; V751-V878 HydrophobicContact CG2-CG1 4.26Å; V751-L881 HydrophobicContact CG2-CB 4.23Å; V751-L881 HydrophobicContact CG2-CD1 4.22Å; V751-L882 HydrophobicContact CB-CD2 4.42Å; V751-L882 HydrophobicContact CG1-CD1 3.68Å; V751-L882 HydrophobicContact CG1-CD2 3.99Å; V751-L882 HydrophobicContact CG1-CG 3.77Å; V751-L882 HydrophobicContact CG2-CD2 4.27Å; V751-L882 HydrophobicContact CG2-CG 4.42Å
752G94.6Very high96.7Very high7 Ų715.1 Ų15.17%0.0728%0.083CC..Hα-helixtrans-95.8-32.6-171.600000115I748 R754I748-G752 WeakPolarHBondContact O-CA 3.23Å; I748-G752 PolarHBondContact O-N 3.16Å; G752-R754 PolarHBondContact O-N 3.31Å; G752-R754 VanDerWaalsContact O-N 3.09Å
753E94.3Very high96.6Very high7 Ų717.7 Ų17.73%0.03310%0.1CC..  trans-87.288.9-176.5-64.1-61.5159.300111Q696 Y749 R770 N832 Y836Q696-E753 PolarHBondContact NE2-O 3.41Å; Y749-E753 HydrophobicContact CD1-CG 4.37Å; Y749-E753 WeakPolarHBondContact O-CB 3.48Å; Y749-E753 PolarHBondContact O-N 2.97Å; E753-R770 IonicContact OE1-CZ 2.72Å; E753-R770 IonicContact OE1-NH2 3.77Å; E753-R770 PolarHBondContact OE1-NH2 3.01Å; E753-R770 IonicContact OE2-CZ 2.68Å; E753-R770 VanDerWaalsContact OE2-CZ 3.3Å; E753-R770 IonicContact OE2-NE 3.38Å; E753-R770 PolarHBondContact OE2-NE 3.06Å; E753-R770 IonicContact OE2-NH2 2.69Å; E753-R770 PolarHBondContact OE2-NH2 3.44Å; E753-N832 PolarHBondContact OE1-ND2 2.77Å; E753-Y836 HydrophobicContact CB-CD1 4.11Å; E753-Y836 HydrophobicContact CB-CE1 4.24Å; E753-Y836 HydrophobicContact CB-CG 4.48Å; E753-Y836 HydrophobicContact CG-CD1 3.44Å; E753-Y836 VanDerWaalsContact CG-CD1 3.44Å; E753-Y836 HydrophobicContact CG-CE1 4.04Å; E753-Y836 HydrophobicContact CG-CG 3.81Å
754R95.5Very high96.2Very high4 Ų424.1 Ų24.12%0.01513%0.127CC..  trans-104.84.8-178.2-52178.8-169-178.6-2.6112.6V751 G752 V756 G760 P869 F871 E924V751-R754 PolarHBondContact O-NE 2.86Å; V751-R754 PolarHBondContact O-NH2 2.73Å; G752-R754 PolarHBondContact O-N 3.31Å; G752-R754 VanDerWaalsContact O-N 3.09Å; R754-V756 PolarHBondContact O-N 3.08Å; R754-G760 VanDerWaalsContact O-CA 3.25Å; R754-G760 WeakPolarHBondContact O-CA 3.4Å; R754-G760 PolarHBondContact O-N 3.43Å; R754-P869 HydrophobicContact CB-CB 4.33Å; R754-P869 HydrophobicContact CB-CG 4.45Å; R754-P869 WeakPolarHBondContact CD-O 3.21Å; R754-P869 PolarHBondContact NH1-O 3.23Å; R754-F871 HydrophobicContact CG-CD1 4.07Å; R754-F871 HydrophobicContact CG-CE1 3.67Å; R754-F871 HydrophobicContact CG-CE2 4.24Å; R754-F871 HydrophobicContact CG-CZ 3.75Å; R754-E924 IonicContact CZ-OE2 2.86Å; R754-E924 VanDerWaalsContact CZ-OE2 3.32Å; R754-E924 IonicContact NH1-OE2 3.73Å; R754-E924 PolarHBondContact NH1-OE2 3.27Å; R754-E924 IonicContact NH2-OE2 3.85Å; R754-E924 PolarHBondContact NH2-OE2 3.35Å
755Y95.6Very high96Very high34 Ų3428.2 Ų28.213%0.13315%0.147CC..  trans-83.251.5-174.9-74.2-100000112.6V762 V767 R770 P869Y755-V762 HydrophobicContact CD1-CG1 4.09Å; Y755-V762 HydrophobicContact CE1-CG1 4.41Å; Y755-V767 WeakPolarHBondContact O-CG2 3.45Å; Y755-R770 HydrophobicContact CD1-CB 4.14Å; Y755-R770 HydrophobicContact CD1-CG 4.47Å; Y755-R770 HydrophobicContact CE1-CB 4.4Å; Y755-R770 VanDerWaalsContact CE2-NH1 3.27Å; Y755-R770 HydrophobicContact CG-CG 4.48Å; Y755-P869 HydrophobicContact CD2-CG 4.03Å; Y755-P869 HydrophobicContact CE1-CG 4.07Å; Y755-P869 VanDerWaalsContact CE2-CD 3.46Å; Y755-P869 HydrophobicContact CE2-CG 3.53Å; Y755-P869 HydrophobicContact CG-CG 4.49Å
756V95.5Very high95.9Very high30 Ų3031 Ų3118%0.18216%0.16CC..SBendtrans-134.9117.7174.4178.40000107.6V620 I693 R754 G758 V759 G760V620-V756 HydrophobicContact CG1-CG1 4.16Å; I693-V756 HydrophobicContact CD1-CG1 4.07Å; I693-V756 HydrophobicContact CD1-CG2 4.34Å; R754-V756 PolarHBondContact O-N 3.08Å; V756-G758 PolarHBondContact O-N 3.22Å; V756-V759 HydrophobicContact CB-CB 4.07Å; V756-V759 HydrophobicContact CB-CG2 3.91Å; V756-V759 HydrophobicContact CG1-CG2 3.98Å; V756-V759 PolarHBondContact O-N 3.37Å; V756-G760 PolarHBondContact O-N 3.43Å; V756-G760 VanDerWaalsContact O-N 3.1Å
757P95.6Very high95.8Very high31 Ų3131.9 Ų31.920%0.20117%0.165CC..BIsolated β-bridgetrans-60.1112.1-177.3-26.134000112.3V620 V762 K764 V767V620-P757 WeakPolarHBondContact CG1-O 3.24Å; P757-V762 HydrophobicContact CG-CG2 4.22Å; P757-K764 HydrophobicContact CG-CG 4.31Å; P757-V767 HydrophobicContact CG-CG2 4.29Å
758G95.5Very high95.6Very high4 Ų433 Ų334%0.04117%0.172CC..THydrogen-bonded Turntrans109.5-19.2-173.800000114S623 V756 G760 C872 F875S623-G758 WeakPolarHBondContact CB-O 3.34Å; S623-G758 PolarHBondContact OG-O 3.35Å; V756-G758 PolarHBondContact O-N 3.22Å; G758-G760 PolarHBondContact N-O 2.92Å; G758-C872 WeakPolarHBondContact O-CB 3.45Å; G758-F875 WeakPolarHBondContact O-CD2 3.36Å; G758-F875 VanDerWaalsContact O-CE2 3.32Å; G758-F875 WeakPolarHBondContact O-CE2 3.48Å
759V97.7Very high95.5Very high0 Ų035 Ų350%018%0.182CC..THydrogen-bonded Turntrans-87.8-55.2162.51790000109V620 I693 V756 F871 C872 F875V620-V759 HydrophobicContact CG2-CG2 3.77Å; I693-V759 HydrophobicContact CG1-CG2 4.23Å; I693-V759 HydrophobicContact CG2-CG2 4.36Å; V756-V759 HydrophobicContact CB-CB 4.07Å; V756-V759 HydrophobicContact CB-CG2 3.91Å; V756-V759 HydrophobicContact CG1-CG2 3.98Å; V756-V759 PolarHBondContact O-N 3.37Å; V759-F871 HydrophobicContact CG1-CD1 4.15Å; V759-F871 HydrophobicContact CG1-CE1 4.04Å; V759-C872 PolarHBondContact O-N 2.97Å; V759-F875 HydrophobicContact CB-CD2 4.49Å; V759-F875 HydrophobicContact CG1-CD1 4.1Å; V759-F875 HydrophobicContact CG1-CE1 4.38Å; V759-F875 HydrophobicContact CG1-CG 4.16Å; V759-F875 HydrophobicContact CG2-CE1 4.27Å; V759-F875 HydrophobicContact CG2-CE2 4.19Å; V759-F875 HydrophobicContact CG2-CZ 3.98Å
760G96.9Very high95.4Very high1 Ų135.4 Ų35.41%0.0118%0.183CC..BIsolated β-bridgetrans-113.7163.1171.400000112.5R754 V756 G758 V762 E870 C872R754-G760 VanDerWaalsContact O-CA 3.25Å; R754-G760 WeakPolarHBondContact O-CA 3.4Å; R754-G760 PolarHBondContact O-N 3.43Å; V756-G760 PolarHBondContact O-N 3.43Å; V756-G760 VanDerWaalsContact O-N 3.1Å; G758-G760 PolarHBondContact N-O 2.92Å; G760-V762 VanDerWaalsContact C-N 3.27Å; G760-V762 PolarHBondContact O-N 3.44Å; G760-E870 CarbonylContact C-O 3.59Å; G760-E870 VanDerWaalsContact CA-O 3.25Å; G760-E870 WeakPolarHBondContact CA-O 3.43Å; G760-C872 PolarHBondContact O-SG 3.45Å; G760-C872 VanDerWaalsContact O-SG 3.39Å
761N94.6Very high95.3Very high117 Ų11735.7 Ų35.763%0.62619%0.185SC*.SBendtrans-78.675.9176.9-169.115.3000110.1E870N761-E870 PolarHBondContact N-O 3.32Å
762V96.1Very high95.3Very high15 Ų1535.7 Ų35.79%0.09119%0.185CC..  trans-136.9153.7-179.8-63.30000111.8Y755 P757 G760 E766 V767 P869Y755-V762 HydrophobicContact CD1-CG1 4.09Å; Y755-V762 HydrophobicContact CE1-CG1 4.41Å; P757-V762 HydrophobicContact CG-CG2 4.22Å; G760-V762 VanDerWaalsContact C-N 3.27Å; G760-V762 PolarHBondContact O-N 3.44Å; V762-E766 HydrophobicContact CB-CB 4.47Å; V762-V767 HydrophobicContact CG2-CG2 4.28Å; V762-P869 HydrophobicContact CG1-CB 3.85Å; V762-P869 HydrophobicContact CG1-CG 3.77Å
763T94.8Very high95.4Very high73 Ų7335.6 Ų35.645%0.44818%0.183SC..  trans-87.1160.3172.164.20000111.9E765 E766 V767T763-E765 PolarHBondContact O-N 3Å; T763-E766 WeakPolarHBondContact CB-OE2 3.26Å; T763-E766 WeakPolarHBondContact CG2-OE2 3.44Å; T763-E766 PolarHBondContact N-OE2 2.95Å; T763-E766 PolarHBondContact O-N 3.39Å; T763-E766 WeakPolarHBondContact OG1-CG 3.16Å; T763-E766 PolarHBondContact OG1-N 2.79Å; T763-E766 PolarHBondContact OG1-OE2 3.48Å; T763-V767 PolarHBondContact O-N 2.97Å
764K91.4Very high95.6Very high135 Ų13535.3 Ų35.359%0.58718%0.181SC*.Hα-helixtrans-58-34.4172.8-73.5-167.4178.1-172.40111.9E551 P757 V767 T768E551-K764 IonicContact OE1-NZ 3.17Å; E551-K764 PolarHBondContact OE1-NZ 3.31Å; P757-K764 HydrophobicContact CG-CG 4.31Å; K764-V767 PolarHBondContact O-N 2.98Å; K764-T768 PolarHBondContact O-N 2.91Å; K764-T768 PolarHBondContact O-OG1 2.87Å
765E93.8Very high95.6Very high86 Ų8635.7 Ų35.740%0.40218%0.183SC..Hα-helixtrans-65.5-39.9178.1-66.2-173.9-168.100112.8T763 V767 T768 M769 V803 K806T763-E765 PolarHBondContact O-N 3Å; E765-V767 VanDerWaalsContact C-N 3.29Å; E765-V767 PolarHBondContact O-N 2.89Å; E765-T768 PolarHBondContact O-N 3.3Å; E765-M769 WeakPolarHBondContact O-CB 3.2Å; E765-M769 VanDerWaalsContact O-CG 3.31Å; E765-M769 WeakPolarHBondContact O-CG 3.41Å; E765-M769 PolarHBondContact O-N 3.34Å; E765-V803 HydrophobicContact CB-CG1 3.86Å; E765-V803 HydrophobicContact CG-CG1 4.17Å; E765-K806 IonicContact OE2-NZ 3.6Å; E765-K806 PolarHBondContact OE2-NZ 2.84Å
766E95.4Very high95.6Very high84 Ų8434.3 Ų34.339%0.39318%0.178SC..Hα-helixtrans-66.6-30.4178.2-74.1161132.100112.4V762 T763 R770V762-E766 HydrophobicContact CB-CB 4.47Å; T763-E766 WeakPolarHBondContact CB-OE2 3.26Å; T763-E766 WeakPolarHBondContact CG2-OE2 3.44Å; T763-E766 PolarHBondContact N-OE2 2.95Å; T763-E766 PolarHBondContact O-N 3.39Å; T763-E766 WeakPolarHBondContact OG1-CG 3.16Å; T763-E766 PolarHBondContact OG1-N 2.79Å; T763-E766 PolarHBondContact OG1-OE2 3.48Å; E766-R770 WeakPolarHBondContact O-CB 3.38Å; E766-R770 PolarHBondContact O-N 3.44Å
767V95.1Very high95.6Very high29 Ų2932.9 Ų32.918%0.17617%0.17CC..Hα-helixtrans-64.5-51.8171.1-172.50000110.6Y755 P757 V762 T763 K764 E765 M769 R770 E771Y755-V767 WeakPolarHBondContact O-CG2 3.45Å; P757-V767 HydrophobicContact CG-CG2 4.29Å; V762-V767 HydrophobicContact CG2-CG2 4.28Å; T763-V767 PolarHBondContact O-N 2.97Å; K764-V767 PolarHBondContact O-N 2.98Å; E765-V767 VanDerWaalsContact C-N 3.29Å; E765-V767 PolarHBondContact O-N 2.89Å; V767-M769 VanDerWaalsContact C-N 3.29Å; V767-M769 PolarHBondContact O-N 3.48Å; V767-R770 WeakPolarHBondContact O-CB 3.45Å; V767-R770 PolarHBondContact O-N 3.36Å; V767-R770 VanDerWaalsContact O-N 3.09Å; V767-E771 PolarHBondContact O-N 2.77Å; V767-E771 VanDerWaalsContact O-N 3.13Å
768T95.3Very high95.6Very high27 Ų2731.8 Ų31.817%0.16616%0.162CC..Hα-helixtrans-62.8-36.1177.6-45.30000111.8K764 E765 E771 I772 L790 T798 V803K764-T768 PolarHBondContact O-N 2.91Å; K764-T768 PolarHBondContact O-OG1 2.87Å; E765-T768 PolarHBondContact O-N 3.3Å; T768-E771 PolarHBondContact O-N 2.83Å; T768-I772 HydrophobicContact CG2-CD1 4.1Å; T768-I772 WeakPolarHBondContact O-CD1 3.47Å; T768-I772 VanDerWaalsContact O-CG1 3.29Å; T768-I772 WeakPolarHBondContact O-CG1 3.49Å; T768-I772 PolarHBondContact O-N 3.05Å; T768-L790 HydrophobicContact CG2-CD1 4.38Å; T768-T798 WeakPolarHBondContact CG2-O 3.47Å; T768-V803 HydrophobicContact CG2-CG2 3.67Å
769M95.9Very high95.6Very high45 Ų4536.4 Ų36.422%0.22218%0.183CC..Hα-helixtrans-61-44.9171.9-76.6175.746.700111.7E765 V767 E771 I772 I773 V803 K806 V807E765-M769 WeakPolarHBondContact O-CB 3.2Å; E765-M769 VanDerWaalsContact O-CG 3.31Å; E765-M769 WeakPolarHBondContact O-CG 3.41Å; E765-M769 PolarHBondContact O-N 3.34Å; V767-M769 VanDerWaalsContact C-N 3.29Å; V767-M769 PolarHBondContact O-N 3.48Å; M769-E771 PolarHBondContact O-N 3.42Å; M769-I772 PolarHBondContact O-N 3.26Å; M769-I773 WeakPolarHBondContact O-CB 3.31Å; M769-I773 WeakPolarHBondContact O-CD1 3.34Å; M769-I773 WeakPolarHBondContact O-CG1 3.41Å; M769-I773 PolarHBondContact O-N 3.27Å; M769-V803 HydrophobicContact CG-CB 3.74Å; M769-V803 HydrophobicContact CG-CG1 3.94Å; M769-V803 HydrophobicContact CG-CG2 4.44Å; M769-K806 HydrophobicContact SD-CB 4.33Å; M769-K806 HydrophobicContact SD-CD 4.09Å; M769-V807 HydrophobicContact CB-CG1 3.88Å; M769-V807 HydrophobicContact CE-CG1 3.73Å; M769-V807 HydrophobicContact CG-CG1 3.75Å; M769-V807 HydrophobicContact SD-CG1 4.36Å
770R95.3Very high95.4Very high13 Ų1339.5 Ų39.55%0.04920%0.203CC..Hα-helixtrans-57.3-48.7177.4-179172.9-174.574.6-5.8111.4E753 Y755 E766 V767 I772 I773 H774 N832 F835E753-R770 IonicContact OE1-CZ 2.72Å; E753-R770 IonicContact OE1-NH2 3.77Å; E753-R770 PolarHBondContact OE1-NH2 3.01Å; E753-R770 IonicContact OE2-CZ 2.68Å; E753-R770 VanDerWaalsContact OE2-CZ 3.3Å; E753-R770 IonicContact OE2-NE 3.38Å; E753-R770 PolarHBondContact OE2-NE 3.06Å; E753-R770 IonicContact OE2-NH2 2.69Å; E753-R770 PolarHBondContact OE2-NH2 3.44Å; Y755-R770 HydrophobicContact CD1-CB 4.14Å; Y755-R770 HydrophobicContact CD1-CG 4.47Å; Y755-R770 HydrophobicContact CE1-CB 4.4Å; Y755-R770 VanDerWaalsContact CE2-NH1 3.27Å; Y755-R770 HydrophobicContact CG-CG 4.48Å; E766-R770 WeakPolarHBondContact O-CB 3.38Å; E766-R770 PolarHBondContact O-N 3.44Å; V767-R770 WeakPolarHBondContact O-CB 3.45Å; V767-R770 PolarHBondContact O-N 3.36Å; V767-R770 VanDerWaalsContact O-N 3.09Å; R770-I772 PolarHBondContact O-N 3.31Å; R770-I773 PolarHBondContact O-N 3.06Å; R770-H774 PolarHBondContact O-N 3.09Å; R770-H774 VanDerWaalsContact O-N 3.08Å; R770-H774 PolarHBondContact O-ND1 3.06Å; R770-N832 PolarHBondContact NH2-ND2 3.25Å; R770-F835 HydrophobicContact CG-CD2 4.4Å; R770-F835 HydrophobicContact CG-CE2 3.97Å
771E95.9Very high95.3Very high7 Ų740.3 Ų40.33%0.03321%0.207CC..Hα-helixtrans-54.4-51.6176.9-67.1-81.4-168.500111.8R684 V767 T768 M769 I773 H774 L775 L790 H837R684-E771 IonicContact CZ-OE1 3.69Å; R684-E771 IonicContact NH2-OE1 3.09Å; R684-E771 PolarHBondContact NH2-OE1 2.73Å; R684-E771 IonicContact NH2-OE2 2.77Å; R684-E771 PolarHBondContact NH2-OE2 3.48Å; V767-E771 PolarHBondContact O-N 2.77Å; V767-E771 VanDerWaalsContact O-N 3.13Å; T768-E771 PolarHBondContact O-N 2.83Å; M769-E771 PolarHBondContact O-N 3.42Å; E771-I773 PolarHBondContact O-N 3.35Å; E771-H774 PolarHBondContact O-N 3Å; E771-L775 WeakPolarHBondContact O-CG 3.39Å; E771-L775 PolarHBondContact O-N 2.98Å; E771-L790 HydrophobicContact CB-CD2 3.34Å; E771-L790 HydrophobicContact CG-CD2 4.02Å; E771-H837 IonicContact OE1-CE1 3.92Å; E771-H837 PolarHBondContact OE1-CE1 3.33Å; E771-H837 IonicContact OE1-ND1 2.85Å; E771-H837 PolarHBondContact OE1-ND1 3.24Å; E771-H837 IonicContact OE2-ND1 2.83Å
772I97Very high95.3Very high0 Ų036.8 Ų36.80%019%0.19CC..Hα-helixtrans-64.4-40.7-178.4-62.1161.3000111.5T768 M769 R770 H774 L775 L776 I786 L790 L800 V803 I804 V807T768-I772 HydrophobicContact CG2-CD1 4.1Å; T768-I772 WeakPolarHBondContact O-CD1 3.47Å; T768-I772 VanDerWaalsContact O-CG1 3.29Å; T768-I772 WeakPolarHBondContact O-CG1 3.49Å; T768-I772 PolarHBondContact O-N 3.05Å; M769-I772 PolarHBondContact O-N 3.26Å; R770-I772 PolarHBondContact O-N 3.31Å; I772-H774 VanDerWaalsContact C-N 3.3Å; I772-H774 PolarHBondContact O-N 3.48Å; I772-L775 PolarHBondContact O-N 3.09Å; I772-L776 HydrophobicContact CG2-CD1 3.76Å; I772-L776 HydrophobicContact CG2-CG 4.19Å; I772-L776 WeakPolarHBondContact O-CB 3.15Å; I772-L776 WeakPolarHBondContact O-CG 3.31Å; I772-L776 PolarHBondContact O-N 2.89Å; I772-I786 HydrophobicContact CG1-CG2 4.05Å; I772-L790 HydrophobicContact CG1-CD1 4.2Å; I772-L790 HydrophobicContact CG1-CD2 4.34Å; I772-L800 HydrophobicContact CD1-CD1 3.43Å; I772-L800 VanDerWaalsContact CD1-CD1 3.43Å; I772-L800 HydrophobicContact CG1-CD1 3.94Å; I772-V803 HydrophobicContact CD1-CG2 3.47Å; I772-V803 VanDerWaalsContact CD1-CG2 3.47Å; I772-I804 HydrophobicContact CG2-CD1 3.78Å; I772-V807 HydrophobicContact CB-CG2 4.07Å; I772-V807 HydrophobicContact CG2-CG2 3.55Å
773I96.8Very high95.1Very high6 Ų639.1 Ų39.13%0.03120%0.2CC..Hα-helixtrans-56.7-47.3175.9-71.4162.5000109.9M769 R770 E771 L776 C777 V807 L823 D830M769-I773 WeakPolarHBondContact O-CB 3.31Å; M769-I773 WeakPolarHBondContact O-CD1 3.34Å; M769-I773 WeakPolarHBondContact O-CG1 3.41Å; M769-I773 PolarHBondContact O-N 3.27Å; R770-I773 PolarHBondContact O-N 3.06Å; E771-I773 PolarHBondContact O-N 3.35Å; I773-L776 PolarHBondContact O-N 2.9Å; I773-C777 WeakPolarHBondContact O-CB 3.5Å; I773-C777 PolarHBondContact O-N 3.42Å; I773-C777 PolarHBondContact O-SG 3.36Å; I773-C777 VanDerWaalsContact O-SG 3.37Å; I773-V807 HydrophobicContact CD1-CG1 3.89Å; I773-V807 HydrophobicContact CG1-CB 4.09Å; I773-V807 HydrophobicContact CG1-CG1 3.83Å; I773-L823 HydrophobicContact CB-CD1 4.36Å; I773-L823 HydrophobicContact CG1-CD1 4.03Å; I773-L823 HydrophobicContact CG2-CD2 4.26Å; I773-D830 HydrophobicContact CD1-CB 4.24Å
774H97.1Very high95Very high1 Ų139.8 Ų39.81%0.00521%0.208CC..Hα-helixtrans-72.5-34.8-177.2-70.686.4000112.9R770 E771 I772 N832 F835 Y838R770-H774 PolarHBondContact O-N 3.09Å; R770-H774 VanDerWaalsContact O-N 3.08Å; R770-H774 PolarHBondContact O-ND1 3.06Å; E771-H774 PolarHBondContact O-N 3Å; I772-H774 VanDerWaalsContact C-N 3.3Å; I772-H774 PolarHBondContact O-N 3.48Å; H774-N832 PolarHBondContact CD2-O 3.24Å; H774-N832 PolarHBondContact NE2-N 2.88Å; H774-N832 PolarHBondContact NE2-O 3.42Å; H774-F835 HydrophobicContact CB-CB 4.49Å; H774-F835 HydrophobicContact CB-CD1 3.33Å; H774-F835 HydrophobicContact CB-CE1 3.54Å; H774-F835 HydrophobicContact CB-CG 3.91Å; H774-F835 HydrophobicContact CB-CZ 4.3Å; H774-F835 WeakPolarHBondContact CD2-CB 3.43Å; H774-F835 AromaticContact CD2-CD1 3.87Å; H774-F835 AromaticContact CD2-CG 3.53Å; H774-F835 AromaticContact CG-CD1 3.48Å; H774-F835 VanDerWaalsContact CG-CD1 3.48Å; H774-F835 AromaticContact CG-CD2 3.97Å; H774-F835 AromaticContact CG-CE1 3.94Å; H774-F835 AromaticContact CG-CG 3.48Å; H774-F835 VanDerWaalsContact CG-CG 3.48Å; H774-F835 AromaticContact ND1-CD2 3.97Å; H774-F835 AromaticContact ND1-CG 3.96Å; H774-Y838 WeakPolarHBondContact CA-OH 3.4Å; H774-Y838 HydrophobicContact CB-CE1 3.87Å; H774-Y838 WeakPolarHBondContact CB-OH 3.33Å; H774-Y838 WeakPolarHBondContact O-CE1 3.35Å; H774-Y838 PolarHBondContact O-OH 3.44Å
775L96.4Very high95.1Very high11 Ų1134.9 Ų34.96%0.05819%0.192CC..Hα-helixtrans-62-50.3170.9-70171000111.4E771 I772 C777 I778 M781 I786 N789 L790E771-L775 WeakPolarHBondContact O-CG 3.39Å; E771-L775 PolarHBondContact O-N 2.98Å; I772-L775 PolarHBondContact O-N 3.09Å; L775-C777 VanDerWaalsContact C-N 3.29Å; L775-C777 PolarHBondContact O-N 3.19Å; L775-I778 WeakPolarHBondContact O-CB 3.21Å; L775-I778 PolarHBondContact O-N 3.4Å; L775-I778 VanDerWaalsContact O-N 3.11Å; L775-M781 HydrophobicContact CB-CE 4.39Å; L775-M781 HydrophobicContact CB-SD 4.16Å; L775-M781 WeakPolarHBondContact O-CE 3.42Å; L775-I786 HydrophobicContact CD1-CG2 4.22Å; L775-N789 HydrophobicContact CD1-CB 3.82Å; L775-N789 HydrophobicContact CD2-CB 3.85Å; L775-L790 HydrophobicContact CD1-CD2 4.44Å
776L96.4Very high95.1Very high5 Ų530.8 Ų30.83%0.02617%0.173CC..Hα-helixtrans-75.8-13.8-177.3-61.9-178.9000114.1I772 I773 M781 I786 A808 Y821 L823I772-L776 HydrophobicContact CG2-CD1 3.76Å; I772-L776 HydrophobicContact CG2-CG 4.19Å; I772-L776 WeakPolarHBondContact O-CB 3.15Å; I772-L776 WeakPolarHBondContact O-CG 3.31Å; I772-L776 PolarHBondContact O-N 2.89Å; I773-L776 PolarHBondContact O-N 2.9Å; L776-M781 HydrophobicContact CD2-CB 3.93Å; L776-M781 HydrophobicContact CD2-CG 4.22Å; L776-I786 HydrophobicContact CD2-CD1 4.02Å; L776-I786 HydrophobicContact CD2-CG1 4.42Å; L776-A808 HydrophobicContact CD1-CB 3.56Å; L776-Y821 WeakPolarHBondContact CD2-O 3.5Å; L776-L823 HydrophobicContact CB-CB 3.86Å; L776-L823 HydrophobicContact CB-CD1 4.26Å; L776-L823 HydrophobicContact CD1-CD1 4.5Å
777C95.3Very high95Very high0 Ų028.1 Ų28.10%017%0.165CC..THydrogen-bonded Turntrans-70.5-17.9167.1-88.60000113.6I773 L775 L823 F831 Q850I773-C777 WeakPolarHBondContact O-CB 3.5Å; I773-C777 PolarHBondContact O-N 3.42Å; I773-C777 PolarHBondContact O-SG 3.36Å; I773-C777 VanDerWaalsContact O-SG 3.37Å; L775-C777 VanDerWaalsContact C-N 3.29Å; L775-C777 PolarHBondContact O-N 3.19Å; C777-L823 WeakPolarHBondContact SG-CD2 3.49Å; C777-F831 HydrophobicContact CB-CD2 3.73Å; C777-F831 HydrophobicContact CB-CE2 4.01Å; C777-F831 VanDerWaalsContact SG-CD2 3.57Å; C777-Q850 PolarHBondContact O-NE2 2.92Å
778I95Very high94.9Very high9 Ų934.8 Ų34.85%0.04619%0.192CC..THydrogen-bonded Turntrans-81.1-59172.6-59.6165.3000109.4L775 Y838 Q842 K845 A846 M849L775-I778 WeakPolarHBondContact O-CB 3.21Å; L775-I778 PolarHBondContact O-N 3.4Å; L775-I778 VanDerWaalsContact O-N 3.11Å; I778-Y838 HydrophobicContact CD1-CD1 4.26Å; I778-Y838 HydrophobicContact CD1-CE1 3.74Å; I778-Y838 HydrophobicContact CG1-CE1 4.11Å; I778-Q842 HydrophobicContact CD1-CB 3.84Å; I778-Q842 HydrophobicContact CD1-CG 3.87Å; I778-K845 HydrophobicContact CG2-CB 4.04Å; I778-K845 HydrophobicContact CG2-CD 4.23Å; I778-A846 HydrophobicContact CG1-CB 4.12Å; I778-M849 WeakPolarHBondContact O-CE 3.41Å
779E94.4Very high94.7Very high100 Ų10036.4 Ų36.447%0.46720%0.2SC..  trans-160.4159.3-178.263.6-166.1155.800111.8M781E779-M781 HydrophobicContact CG-CE 3.79Å; E779-M781 HydrophobicContact CG-CG 4.27Å
780P94.8Very high94.6Very high65 Ų6534.5 Ų34.542%0.42219%0.19SC..  trans-63.1134.1170-22.735.7000112V820 Y821 E822P780-V820 HydrophobicContact CB-CB 4.2Å; P780-V820 HydrophobicContact CB-CG2 3.93Å; P780-Y821 VanDerWaalsContact CA-O 3.3Å; P780-Y821 WeakPolarHBondContact CA-O 3.41Å; P780-E822 HydrophobicContact CB-CG 3.76Å; P780-E822 HydrophobicContact CG-CG 3.81Å
781M95.3Very high94.3Very high19 Ų1935 Ų359%0.09420%0.195CC..BIsolated β-bridgetrans-128.5144.2-173.2-65.3-176.5-172.800113.1L775 L776 E779 A785 I786 Y821L775-M781 HydrophobicContact CB-CE 4.39Å; L775-M781 HydrophobicContact CB-SD 4.16Å; L775-M781 WeakPolarHBondContact O-CE 3.42Å; L776-M781 HydrophobicContact CD2-CB 3.93Å; L776-M781 HydrophobicContact CD2-CG 4.22Å; E779-M781 HydrophobicContact CG-CE 3.79Å; E779-M781 HydrophobicContact CG-CG 4.27Å; M781-A785 HydrophobicContact CB-CB 4.35Å; M781-I786 HydrophobicContact CB-CD1 4.28Å; M781-I786 HydrophobicContact CB-CG1 3.7Å; M781-Y821 PolarHBondContact N-O 3.02Å; M781-Y821 PolarHBondContact O-N 3.28Å
782P94.3Very high93.8Very high43 Ų4339.5 Ų39.528%0.27922%0.216SC..  trans-71.5158.6169.531.9-35.6000111.2S784 A785 I786P782-S784 VanDerWaalsContact C-N 3.32Å; P782-S784 PolarHBondContact O-N 3.02Å; P782-A785 HydrophobicContact CG-CB 3.79Å; P782-A785 PolarHBondContact O-N 3.07Å; P782-I786 PolarHBondContact O-N 3.44Å
783H92.3Very high93Very high63 Ų6342.5 Ų42.529%0.29223%0.232SC..Hα-helixtrans-50.2-47.5-175.3-169.8-113.9000114A785 I786 A787 L800 E801 Y821H783-A785 VanDerWaalsContact C-N 3.32Å; H783-A785 PolarHBondContact O-N 2.96Å; H783-I786 PolarHBondContact O-N 3.19Å; H783-A787 WeakPolarHBondContact O-CB 3.42Å; H783-A787 PolarHBondContact O-N 3.23Å; H783-L800 WeakPolarHBondContact NE2-CD2 3.23Å; H783-E801 IonicContact CE1-OE1 3.55Å; H783-E801 PolarHBondContact CE1-OE1 3.32Å; H783-E801 IonicContact NE2-OE1 3.27Å; H783-E801 PolarHBondContact NE2-OE1 2.92Å; H783-E801 IonicContact NE2-OE2 3.61Å; H783-Y821 HydrophobicContact CB-CE2 4.05Å
784S90.8Very high91.8Very high88 Ų8844.1 Ų44.162%0.61524%0.24SC*.Hα-helixtrans-65.1-31.4-17950.60000113.6P782 K788P782-S784 VanDerWaalsContact C-N 3.32Å; P782-S784 PolarHBondContact O-N 3.02Å; S784-K788 WeakPolarHBondContact O-CB 3.43Å; S784-K788 PolarHBondContact O-N 3.48Å
785A94.1Very high90.6Very high31 Ų3146.4 Ų46.426%0.25625%0.252SS..Hα-helixtrans-72.9-38.317600000111.5M781 P782 H783 N789M781-A785 HydrophobicContact CB-CB 4.35Å; P782-A785 HydrophobicContact CG-CB 3.79Å; P782-A785 PolarHBondContact O-N 3.07Å; H783-A785 VanDerWaalsContact C-N 3.32Å; H783-A785 PolarHBondContact O-N 2.96Å; A785-N789 PolarHBondContact O-N 3.25Å; A785-N789 PolarHBondContact O-ND2 3.42Å
786I94.5Very high89.7Confident0 Ų049 Ų490%027%0.266CS..Hα-helixtrans-64.8-52.3173.6-55.2171.5000109.3I772 L775 L776 M781 P782 H783 K788 N789 L790 L800 I804 Y821I772-I786 HydrophobicContact CG1-CG2 4.05Å; L775-I786 HydrophobicContact CD1-CG2 4.22Å; L776-I786 HydrophobicContact CD2-CD1 4.02Å; L776-I786 HydrophobicContact CD2-CG1 4.42Å; M781-I786 HydrophobicContact CB-CD1 4.28Å; M781-I786 HydrophobicContact CB-CG1 3.7Å; P782-I786 PolarHBondContact O-N 3.44Å; H783-I786 PolarHBondContact O-N 3.19Å; I786-K788 VanDerWaalsContact C-N 3.29Å; I786-K788 PolarHBondContact O-N 3.03Å; I786-N789 PolarHBondContact O-N 3.19Å; I786-L790 HydrophobicContact CG2-CD1 4.06Å; I786-L790 HydrophobicContact CG2-CG 4.44Å; I786-L790 WeakPolarHBondContact O-CG 3.34Å; I786-L790 PolarHBondContact O-N 3.35Å; I786-L800 HydrophobicContact CB-CD1 4.46Å; I786-L800 HydrophobicContact CB-CD2 4.06Å; I786-L800 HydrophobicContact CG2-CD1 3.64Å; I786-L800 HydrophobicContact CG2-CD2 3.95Å; I786-L800 HydrophobicContact CG2-CG 4.49Å; I786-I804 HydrophobicContact CD1-CD1 4.02Å; I786-Y821 HydrophobicContact CD1-CD2 3.92Å; I786-Y821 HydrophobicContact CD1-CG 4.23Å
787A92.5Very high89Confident29 Ų2951.4 Ų51.424%0.2428%0.277CS..Hα-helixtrans-55.2-41.8-179.600000112.9H783 N789 L790 L800H783-A787 WeakPolarHBondContact O-CB 3.42Å; H783-A787 PolarHBondContact O-N 3.23Å; A787-N789 PolarHBondContact O-N 2.97Å; A787-L790 PolarHBondContact O-N 3.42Å; A787-L800 HydrophobicContact CB-CD2 3.87Å
788K92.4Very high88.5Confident169 Ų16952.7 Ų52.774%0.73529%0.285SS*.Hα-helixtrans-64-24177.7-176.8177.4176.7-174.90114S784 I786S784-K788 WeakPolarHBondContact O-CB 3.43Å; S784-K788 PolarHBondContact O-N 3.48Å; I786-K788 VanDerWaalsContact C-N 3.29Å; I786-K788 PolarHBondContact O-N 3.03Å
789N92.4Very high88.2Confident60 Ų6053.4 Ų53.432%0.32129%0.294SS..THydrogen-bonded Turntrans-101.18.9-179.8-71.7-86000113L775 A785 I786 A787L775-N789 HydrophobicContact CD1-CB 3.82Å; L775-N789 HydrophobicContact CD2-CB 3.85Å; A785-N789 PolarHBondContact O-N 3.25Å; A785-N789 PolarHBondContact O-ND2 3.42Å; I786-N789 PolarHBondContact O-N 3.19Å; A787-N789 PolarHBondContact O-N 2.97Å
790L93.1Very high88Confident6 Ų648.7 Ų48.73%0.03127%0.273CS..SBendtrans-105.9148.4173.3-68.6175.5000110.9V681 T768 E771 I772 L775 I786 A787 T798 L800V681-L790 VanDerWaalsContact CG2-C 3.42Å; T768-L790 HydrophobicContact CG2-CD1 4.38Å; E771-L790 HydrophobicContact CB-CD2 3.34Å; E771-L790 HydrophobicContact CG-CD2 4.02Å; I772-L790 HydrophobicContact CG1-CD1 4.2Å; I772-L790 HydrophobicContact CG1-CD2 4.34Å; L775-L790 HydrophobicContact CD1-CD2 4.44Å; I786-L790 HydrophobicContact CG2-CD1 4.06Å; I786-L790 HydrophobicContact CG2-CG 4.44Å; I786-L790 WeakPolarHBondContact O-CG 3.34Å; I786-L790 PolarHBondContact O-N 3.35Å; A787-L790 PolarHBondContact O-N 3.42Å; L790-T798 HydrophobicContact CB-CG2 3.85Å; L790-L800 HydrophobicContact CD1-CB 3.85Å; L790-L800 HydrophobicContact CD1-CD1 4Å; L790-L800 HydrophobicContact CD1-CD2 4.25Å; L790-L800 HydrophobicContact CD1-CG 4.26Å
791P88.8Confident87.7Confident23 Ų2350 Ų5015%0.14927%0.273CS..  trans-65.8144.1173.127.4-33.4000111.2E685 T798E685-P791 VanDerWaalsContact CD-CB 3.4Å; E685-P791 HydrophobicContact CG-CB 4.03Å; E685-P791 HydrophobicContact CG-CG 4.4Å; E685-P791 VanDerWaalsContact OE1-CG 3.3Å; E685-P791 WeakPolarHBondContact OE1-CG 3.42Å; E685-P791 WeakPolarHBondContact OE2-CB 3.14Å; P791-T798 WeakPolarHBondContact O-CA 3.17Å
792E86.1Confident87.3Confident101 Ų10154.4 Ų54.447%0.47230%0.297SS..  trans-98.5132.2175.6-72.1-177.1161.700110.6T798E792-T798 HydrophobicContact CG-CG2 4.07Å
793N80.1Confident87.3Confident64 Ų6452.4 Ų52.434%0.34228%0.284SS..  trans-77.1-179.4172.971.617.6000112.5N795 N796 E797N793-N795 PolarHBondContact O-N 3.49Å; N793-N795 WeakPolarHBondContact OD1-CA 3.34Å; N793-N795 WeakPolarHBondContact OD1-CB 3.39Å; N793-N795 PolarHBondContact OD1-N 3.34Å; N793-N796 WeakPolarHBondContact O-CA 3.44Å; N793-N796 PolarHBondContact O-N 2.97Å; N793-N796 PolarHBondContact OD1-N 3.48Å; N793-E797 PolarHBondContact N-O 2.95Å; N793-E797 PolarHBondContact ND2-O 3.15Å; N793-E797 PolarHBondContact OD1-N 3.48Å; N793-E797 PolarHBondContact OD1-O 2.99Å
794E71.3Confident87.4Confident39 Ų3949.4 Ų49.418%0.18227%0.27CS..THydrogen-bonded Turntrans-53.1-27.4179.3-65.4163.8-157.500114.4K480 L547 M548K480-E794 PolarHBondContact NZ-O 3.18Å; L547-E794 HydrophobicContact CD2-CG 4.46Å; M548-E794 HydrophobicContact CG-CG 3.9Å; M548-E794 VanDerWaalsContact CG-OE1 3.26Å; M548-E794 WeakPolarHBondContact CG-OE1 3.44Å; M548-E794 HydrophobicContact SD-CG 4.23Å
795N72.3Confident87.5Confident49 Ų4950.3 Ų50.326%0.26227%0.268SS..THydrogen-bonded Turntrans-89.92.2178.9-67.7-26.2000114R113 P119 N793 E797R113-N795 PolarHBondContact NH1-O 3.03Å; P119-N795 WeakPolarHBondContact CD-OD1 3.38Å; P119-N795 HydrophobicContact CG-CB 4.24Å; N793-N795 PolarHBondContact O-N 3.49Å; N793-N795 WeakPolarHBondContact OD1-CA 3.34Å; N793-N795 WeakPolarHBondContact OD1-CB 3.39Å; N793-N795 PolarHBondContact OD1-N 3.34Å; N795-E797 HydrophobicContact CB-CG 4.47Å
796N76.8Confident87.6Confident65 Ų6553.6 Ų53.635%0.34828%0.277SS..SBendtrans58.344.3-168.9-45.7-42000112.1N793N793-N796 WeakPolarHBondContact O-CA 3.44Å; N793-N796 PolarHBondContact O-N 2.97Å; N793-N796 PolarHBondContact OD1-N 3.48Å
797E81.8Confident87.6Confident56 Ų5653.6 Ų53.626%0.26228%0.277SS..  trans-118.6147.1170.6-63.9-167.3129.900111.3R137 N793 N795R137-E797 IonicContact CZ-OE1 2.83Å; R137-E797 IonicContact NH1-OE1 2.75Å; R137-E797 IonicContact NH2-OE1 3.32Å; R137-E797 PolarHBondContact NH2-OE1 3.46Å; N793-E797 PolarHBondContact N-O 2.95Å; N793-E797 PolarHBondContact ND2-O 3.15Å; N793-E797 PolarHBondContact OD1-N 3.48Å; N793-E797 PolarHBondContact OD1-O 2.99Å; N795-E797 HydrophobicContact CB-CG 4.47Å
798T86.4Confident87.8Confident27 Ų2752.3 Ų52.317%0.16627%0.266CS..  trans-101.8-4.7-177.458.60000114.4T768 L790 P791 E792 L800T768-T798 WeakPolarHBondContact CG2-O 3.47Å; L790-T798 HydrophobicContact CB-CG2 3.85Å; P791-T798 WeakPolarHBondContact O-CA 3.17Å; E792-T798 HydrophobicContact CG-CG2 4.07Å; T798-L800 PolarHBondContact O-N 2.91Å; T798-L800 WeakPolarHBondContact OG1-CB 3.36Å
799G86.8Confident88Confident24 Ų2447.8 Ų47.825%0.24725%0.252CS..SBendtrans72.5-3.8-172.900000115.5E801 N802G799-E801 VanDerWaalsContact C-N 3.35Å; G799-E801 PolarHBondContact O-N 3.43Å; G799-N802 WeakPolarHBondContact O-CB 3.38Å; G799-N802 PolarHBondContact O-N 3.33Å; G799-N802 VanDerWaalsContact O-N 3.12Å
800L91.7Very high88.1Confident2 Ų249.9 Ų49.91%0.0126%0.259CS..Hα-helixtrans-48.9-47.8-174.5177.654.5000114.2I772 H783 I786 A787 L790 T798 N802 V803 I804I772-L800 HydrophobicContact CD1-CD1 3.43Å; I772-L800 VanDerWaalsContact CD1-CD1 3.43Å; I772-L800 HydrophobicContact CG1-CD1 3.94Å; H783-L800 WeakPolarHBondContact NE2-CD2 3.23Å; I786-L800 HydrophobicContact CB-CD1 4.46Å; I786-L800 HydrophobicContact CB-CD2 4.06Å; I786-L800 HydrophobicContact CG2-CD1 3.64Å; I786-L800 HydrophobicContact CG2-CD2 3.95Å; I786-L800 HydrophobicContact CG2-CG 4.49Å; A787-L800 HydrophobicContact CB-CD2 3.87Å; L790-L800 HydrophobicContact CD1-CB 3.85Å; L790-L800 HydrophobicContact CD1-CD1 4Å; L790-L800 HydrophobicContact CD1-CD2 4.25Å; L790-L800 HydrophobicContact CD1-CG 4.26Å; T798-L800 PolarHBondContact O-N 2.91Å; T798-L800 WeakPolarHBondContact OG1-CB 3.36Å; L800-N802 PolarHBondContact O-N 2.88Å; L800-V803 PolarHBondContact O-N 3.2Å; L800-V803 VanDerWaalsContact O-N 3.12Å; L800-I804 HydrophobicContact CD1-CB 3.86Å; L800-I804 HydrophobicContact CD1-CD1 3.98Å; L800-I804 HydrophobicContact CD1-CG1 4.16Å; L800-I804 HydrophobicContact CG-CB 4.49Å; L800-I804 WeakPolarHBondContact O-CB 3.46Å; L800-I804 PolarHBondContact O-N 3.39Å
801E88.1Confident88.1Confident92 Ų9254.4 Ų54.443%0.4328%0.278SS..Hα-helixtrans-58.2-32.8-176.7-58.9-69.3-17600113.1H783 G799 V803H783-E801 IonicContact CE1-OE1 3.55Å; H783-E801 PolarHBondContact CE1-OE1 3.32Å; H783-E801 IonicContact NE2-OE1 3.27Å; H783-E801 PolarHBondContact NE2-OE1 2.92Å; H783-E801 IonicContact NE2-OE2 3.61Å; G799-E801 VanDerWaalsContact C-N 3.35Å; G799-E801 PolarHBondContact O-N 3.43Å; E801-V803 VanDerWaalsContact C-N 3.3Å; E801-V803 PolarHBondContact O-N 2.85Å
802N87.5Confident87.9Confident111 Ų11161.6 Ų61.659%0.59431%0.307SS*.Hα-helixtrans-74-22-177.2-61.8-20.8000112.7G799 L800 K806G799-N802 WeakPolarHBondContact O-CB 3.38Å; G799-N802 PolarHBondContact O-N 3.33Å; G799-N802 VanDerWaalsContact O-N 3.12Å; L800-N802 PolarHBondContact O-N 2.88Å; N802-K806 WeakPolarHBondContact O-CE 3.07Å
803V93.6Very high87.9Confident1 Ų159.9 Ų59.91%0.00631%0.305CS..Hα-helixtrans-126.2-20.2-167.7-650000114.8E765 T768 M769 I772 L800 E801 N805 K806 V807E765-V803 HydrophobicContact CB-CG1 3.86Å; E765-V803 HydrophobicContact CG-CG1 4.17Å; T768-V803 HydrophobicContact CG2-CG2 3.67Å; M769-V803 HydrophobicContact CG-CB 3.74Å; M769-V803 HydrophobicContact CG-CG1 3.94Å; M769-V803 HydrophobicContact CG-CG2 4.44Å; I772-V803 HydrophobicContact CD1-CG2 3.47Å; I772-V803 VanDerWaalsContact CD1-CG2 3.47Å; L800-V803 PolarHBondContact O-N 3.2Å; L800-V803 VanDerWaalsContact O-N 3.12Å; E801-V803 VanDerWaalsContact C-N 3.3Å; E801-V803 PolarHBondContact O-N 2.85Å; V803-N805 VanDerWaalsContact C-N 3.3Å; V803-N805 PolarHBondContact O-N 2.96Å; V803-K806 WeakPolarHBondContact O-CA 3.34Å; V803-K806 VanDerWaalsContact O-CB 3.25Å; V803-K806 WeakPolarHBondContact O-CB 3.48Å; V803-K806 PolarHBondContact O-N 3.19Å; V803-V807 PolarHBondContact O-N 3.27Å
804I94.2Very high87.7Confident0 Ų059.7 Ų59.70%032%0.318CS..Hα-helixtrans-56.4-42.9-174-172.256.9000112.6I772 I786 L800 K806 V807 A808 Y821I772-I804 HydrophobicContact CG2-CD1 3.78Å; I786-I804 HydrophobicContact CD1-CD1 4.02Å; L800-I804 HydrophobicContact CD1-CB 3.86Å; L800-I804 HydrophobicContact CD1-CD1 3.98Å; L800-I804 HydrophobicContact CD1-CG1 4.16Å; L800-I804 HydrophobicContact CG-CB 4.49Å; L800-I804 WeakPolarHBondContact O-CB 3.46Å; L800-I804 PolarHBondContact O-N 3.39Å; I804-K806 PolarHBondContact O-N 3.4Å; I804-V807 PolarHBondContact O-N 3.41Å; I804-A808 HydrophobicContact CD1-CB 3.76Å; I804-A808 HydrophobicContact CG1-CB 4.45Å; I804-A808 WeakPolarHBondContact O-CB 3.43Å; I804-A808 PolarHBondContact O-N 2.94Å; I804-Y821 HydrophobicContact CD1-CD1 3.89Å; I804-Y821 HydrophobicContact CD1-CD2 4.38Å; I804-Y821 HydrophobicContact CD1-CE1 4.31Å; I804-Y821 HydrophobicContact CD1-CG 3.92Å; I804-Y821 HydrophobicContact CG1-CD1 3.55Å; I804-Y821 HydrophobicContact CG1-CD2 4.26Å; I804-Y821 HydrophobicContact CG1-CE1 3.46Å; I804-Y821 VanDerWaalsContact CG1-CE1 3.46Å; I804-Y821 HydrophobicContact CG1-CE2 4.19Å; I804-Y821 HydrophobicContact CG1-CG 3.95Å; I804-Y821 HydrophobicContact CG2-CE1 4.49Å
805N93.8Very high87.7Confident108 Ų10865.7 Ų65.758%0.57836%0.357SS*.Hα-helixtrans-70.5-14.1177.9-68.2-50.8000113.7V803 K824V803-N805 VanDerWaalsContact C-N 3.3Å; V803-N805 PolarHBondContact O-N 2.96Å; N805-K824 PolarHBondContact O-NZ 3.03Å
806K95.2Very high87Confident100 Ų10069.4 Ų69.444%0.43539%0.387SS..Hα-helixtrans-76.9-45.5173.7-55.6-174.9-176.1-173.80110.3E765 M769 N802 V803 I804 K824E765-K806 IonicContact OE2-NZ 3.6Å; E765-K806 PolarHBondContact OE2-NZ 2.84Å; M769-K806 HydrophobicContact SD-CB 4.33Å; M769-K806 HydrophobicContact SD-CD 4.09Å; N802-K806 WeakPolarHBondContact O-CE 3.07Å; V803-K806 WeakPolarHBondContact O-CA 3.34Å; V803-K806 VanDerWaalsContact O-CB 3.25Å; V803-K806 WeakPolarHBondContact O-CB 3.48Å; V803-K806 PolarHBondContact O-N 3.19Å; I804-K806 PolarHBondContact O-N 3.4Å; K806-K824 WeakPolarHBondContact O-CD 3.3Å; K806-K824 WeakPolarHBondContact O-CE 3.46Å; K806-K824 PolarHBondContact O-NZ 3.35Å
807V96Very high86.8Confident0 Ų068.2 Ų68.20%039%0.39CS..Hα-helixtrans-96.6-26.7-173.6-64.90000115.2M769 I772 I773 V803 I804 L823 K824M769-V807 HydrophobicContact CB-CG1 3.88Å; M769-V807 HydrophobicContact CE-CG1 3.73Å; M769-V807 HydrophobicContact CG-CG1 3.75Å; M769-V807 HydrophobicContact SD-CG1 4.36Å; I772-V807 HydrophobicContact CB-CG2 4.07Å; I772-V807 HydrophobicContact CG2-CG2 3.55Å; I773-V807 HydrophobicContact CD1-CG1 3.89Å; I773-V807 HydrophobicContact CG1-CB 4.09Å; I773-V807 HydrophobicContact CG1-CG1 3.83Å; V803-V807 PolarHBondContact O-N 3.27Å; I804-V807 PolarHBondContact O-N 3.41Å; V807-L823 HydrophobicContact CB-CD1 4.41Å; V807-L823 WeakPolarHBondContact O-CD1 3.28Å; V807-K824 WeakPolarHBondContact O-CB 3.46Å; V807-K824 WeakPolarHBondContact O-CG 3.4Å; V807-K824 PolarHBondContact O-N 2.87Å
808A96.6Very high86.7Confident2 Ų273.7 Ų73.72%0.01742%0.415CS..EExtended strand (participates in β ladder)trans-127164.5-171.200000113.2L776 I804 Y821 E822 K824L776-A808 HydrophobicContact CD1-CB 3.56Å; I804-A808 HydrophobicContact CD1-CB 3.76Å; I804-A808 HydrophobicContact CG1-CB 4.45Å; I804-A808 WeakPolarHBondContact O-CB 3.43Å; I804-A808 PolarHBondContact O-N 2.94Å; A808-Y821 HydrophobicContact CB-CD1 4.06Å; A808-Y821 HydrophobicContact CB-CG 4.47Å; A808-E822 CarbonylContact C-O 3.51Å; A808-E822 VanDerWaalsContact CA-O 3.26Å; A808-E822 WeakPolarHBondContact CA-O 3.4Å; A808-E822 WeakPolarHBondContact CB-O 3.4Å; A808-K824 VanDerWaalsContact O-CE 3.23Å; A808-K824 WeakPolarHBondContact O-CE 3.38Å
809T95.7Very high86.9Confident73 Ų7373 Ų7345%0.44841%0.414SS..EExtended strand (participates in β ladder)trans-117.1131.9170.448.30000109.9K811 Y821 E822 K824T809-K811 PolarHBondContact O-N 3.44Å; T809-Y821 WeakPolarHBondContact O-CA 3.35Å; T809-E822 PolarHBondContact N-O 3.48Å; T809-E822 PolarHBondContact O-N 3.03Å; T809-E822 PolarHBondContact OG1-O 3.41Å; T809-K824 HydrophobicContact CG2-CG 3.99Å
810F94.8Very high87.2Confident104 Ų10473.7 Ų73.746%0.45641%0.413SS..EExtended strand (participates in β ladder)trans-78.2121.4176-177.4-107.7000111.1K812 Y821F810-K812 HydrophobicContact CD1-CG 4.42Å; F810-K812 HydrophobicContact CE1-CG 4.16Å; F810-Y821 HydrophobicContact CB-CD1 4.04Å; F810-Y821 HydrophobicContact CB-CE1 3.68Å; F810-Y821 HydrophobicContact CD2-CD1 4.28Å; F810-Y821 HydrophobicContact CD2-CD2 4.25Å; F810-Y821 AromaticContact CD2-CE1 3.95Å; F810-Y821 HydrophobicContact CD2-CE1 3.95Å; F810-Y821 AromaticContact CD2-CE2 3.91Å; F810-Y821 HydrophobicContact CD2-CE2 3.91Å; F810-Y821 HydrophobicContact CD2-CG 4.43Å; F810-Y821 AromaticContact CD2-CZ 3.75Å; F810-Y821 HydrophobicContact CE2-CE2 4.45Å; F810-Y821 HydrophobicContact CG-CE1 4.27Å
811K92Very high87.4Confident101 Ų10174.9 Ų74.944%0.43942%0.418SS..EExtended strand (participates in β ladder)trans-98.5114.7174-170166.2-174.8166.50109T809 G819 V820 E822T809-K811 PolarHBondContact O-N 3.44Å; K811-G819 VanDerWaalsContact O-CA 3.31Å; K811-G819 WeakPolarHBondContact O-CA 3.12Å; K811-V820 HydrophobicContact CB-CG2 4.17Å; K811-V820 WeakPolarHBondContact CB-O 3.43Å; K811-V820 PolarHBondContact N-O 3.14Å; K811-V820 PolarHBondContact O-N 3.45Å; K811-V820 VanDerWaalsContact O-N 3.08Å; K811-E822 HydrophobicContact CD-CG 4.19Å; K811-E822 VanDerWaalsContact CD-OE1 3.26Å; K811-E822 WeakPolarHBondContact CD-OE1 3.39Å; K811-E822 VanDerWaalsContact CD-OE2 3.28Å; K811-E822 WeakPolarHBondContact CD-OE2 3.49Å; K811-E822 IonicContact NZ-OE1 3.19Å; K811-E822 PolarHBondContact NZ-OE1 3.29Å; K811-E822 IonicContact NZ-OE2 2.63Å; K811-E822 PolarHBondContact NZ-OE2 3.44Å
812K86.5Confident87.8Confident174 Ų17473.4 Ų73.476%0.75741%0.411SS*.  trans-56.9144.9176.8-68.2-172.9178.4-174.30110.4F810F810-K812 HydrophobicContact CD1-CG 4.42Å; F810-K812 HydrophobicContact CE1-CG 4.16Å
813P84.6Confident88.2Confident65 Ų6568.9 Ų68.942%0.42239%0.387SS..  trans-59.8150.3175.324.8-32.7000111.7G817P813-G817 VanDerWaalsContact CB-C 3.48Å; P813-G817 WeakPolarHBondContact CB-O 3.44Å
814G76.3Confident88.3Confident61 Ų6171.6 Ų71.663%0.62940%0.398SS*.  trans-72.3-173.8158.900000111.4S816 G817G814-S816 PolarHBondContact O-N 3.39Å; G814-G817 PolarHBondContact O-N 3.21Å
815V71.8Confident88.2Confident164 Ų16477.4 Ų77.499%0.99443%0.43SS*.THydrogen-bonded Turntrans-56.7-20-172.3-170.50000114.4
816S58.1Low88.1Confident127 Ų12779.7 Ų79.789%0.88844%0.437SS*.THydrogen-bonded Turntrans-137.823.2-176.662.60000114.6G814G814-S816 PolarHBondContact O-N 3.39Å
817G71.9Confident88.1Confident41 Ų4175.5 Ų75.542%0.42342%0.42SS..  trans-116.9174.9-174.400000115.1P813 G814P813-G817 VanDerWaalsContact CB-C 3.48Å; P813-G817 WeakPolarHBondContact CB-O 3.44Å; G814-G817 PolarHBondContact O-N 3.21Å
818H79.8Confident87.8Confident170 Ų17077.2 Ų77.279%0.78743%0.429SS*.  trans-99.2151.4160.5-59.5-65.2000109.9
819G89.6Confident87.6Confident14 Ų1484 Ų8414%0.14446%0.458CS..  trans-71.5142.3177.500000111.7K811K811-G819 VanDerWaalsContact O-CA 3.31Å; K811-G819 WeakPolarHBondContact O-CA 3.12Å
820V94.4Very high87.5Confident37 Ų3782.8 Ų82.822%0.22445%0.449CS..EExtended strand (participates in β ladder)trans-125.6152-176.1-62.40000111P780 K811P780-V820 HydrophobicContact CB-CB 4.2Å; P780-V820 HydrophobicContact CB-CG2 3.93Å; K811-V820 HydrophobicContact CB-CG2 4.17Å; K811-V820 WeakPolarHBondContact CB-O 3.43Å; K811-V820 PolarHBondContact N-O 3.14Å; K811-V820 PolarHBondContact O-N 3.45Å; K811-V820 VanDerWaalsContact O-N 3.08Å
821Y96.3Very high87.5Confident27 Ų2778.6 Ų78.611%0.10643%0.431CS..EExtended strand (participates in β ladder)trans-91.5130.6170.1-71.5-84000109.8L776 P780 M781 H783 I786 I804 A808 T809 F810L776-Y821 WeakPolarHBondContact CD2-O 3.5Å; P780-Y821 VanDerWaalsContact CA-O 3.3Å; P780-Y821 WeakPolarHBondContact CA-O 3.41Å; M781-Y821 PolarHBondContact N-O 3.02Å; M781-Y821 PolarHBondContact O-N 3.28Å; H783-Y821 HydrophobicContact CB-CE2 4.05Å; I786-Y821 HydrophobicContact CD1-CD2 3.92Å; I786-Y821 HydrophobicContact CD1-CG 4.23Å; I804-Y821 HydrophobicContact CD1-CD1 3.89Å; I804-Y821 HydrophobicContact CD1-CD2 4.38Å; I804-Y821 HydrophobicContact CD1-CE1 4.31Å; I804-Y821 HydrophobicContact CD1-CG 3.92Å; I804-Y821 HydrophobicContact CG1-CD1 3.55Å; I804-Y821 HydrophobicContact CG1-CD2 4.26Å; I804-Y821 HydrophobicContact CG1-CE1 3.46Å; I804-Y821 VanDerWaalsContact CG1-CE1 3.46Å; I804-Y821 HydrophobicContact CG1-CE2 4.19Å; I804-Y821 HydrophobicContact CG1-CG 3.95Å; I804-Y821 HydrophobicContact CG2-CE1 4.49Å; A808-Y821 HydrophobicContact CB-CD1 4.06Å; A808-Y821 HydrophobicContact CB-CG 4.47Å; T809-Y821 WeakPolarHBondContact O-CA 3.35Å; F810-Y821 HydrophobicContact CB-CD1 4.04Å; F810-Y821 HydrophobicContact CB-CE1 3.68Å; F810-Y821 HydrophobicContact CD2-CD1 4.28Å; F810-Y821 HydrophobicContact CD2-CD2 4.25Å; F810-Y821 AromaticContact CD2-CE1 3.95Å; F810-Y821 HydrophobicContact CD2-CE1 3.95Å; F810-Y821 AromaticContact CD2-CE2 3.91Å; F810-Y821 HydrophobicContact CD2-CE2 3.91Å; F810-Y821 HydrophobicContact CD2-CG 4.43Å; F810-Y821 AromaticContact CD2-CZ 3.75Å; F810-Y821 HydrophobicContact CE2-CE2 4.45Å; F810-Y821 HydrophobicContact CG-CE1 4.27Å
822E95.1Very high87.7Confident62 Ų6274.1 Ų74.129%0.2941%0.411SS..EExtended strand (participates in β ladder)trans-107.6138.9171.4-69-173.316200109.1P780 A808 T809 K811P780-E822 HydrophobicContact CB-CG 3.76Å; P780-E822 HydrophobicContact CG-CG 3.81Å; A808-E822 CarbonylContact C-O 3.51Å; A808-E822 VanDerWaalsContact CA-O 3.26Å; A808-E822 WeakPolarHBondContact CA-O 3.4Å; A808-E822 WeakPolarHBondContact CB-O 3.4Å; T809-E822 PolarHBondContact N-O 3.48Å; T809-E822 PolarHBondContact O-N 3.03Å; T809-E822 PolarHBondContact OG1-O 3.41Å; K811-E822 HydrophobicContact CD-CG 4.19Å; K811-E822 VanDerWaalsContact CD-OE1 3.26Å; K811-E822 WeakPolarHBondContact CD-OE1 3.39Å; K811-E822 VanDerWaalsContact CD-OE2 3.28Å; K811-E822 WeakPolarHBondContact CD-OE2 3.49Å; K811-E822 IonicContact NZ-OE1 3.19Å; K811-E822 PolarHBondContact NZ-OE1 3.29Å; K811-E822 IonicContact NZ-OE2 2.63Å; K811-E822 PolarHBondContact NZ-OE2 3.44Å
823L95.9Very high88Confident15 Ų1566.6 Ų66.68%0.07938%0.379CS..EExtended strand (participates in β ladder)trans-67.5137.8179.7-170.666.5000111I773 L776 C777 V807 L828I773-L823 HydrophobicContact CB-CD1 4.36Å; I773-L823 HydrophobicContact CG1-CD1 4.03Å; I773-L823 HydrophobicContact CG2-CD2 4.26Å; L776-L823 HydrophobicContact CB-CB 3.86Å; L776-L823 HydrophobicContact CB-CD1 4.26Å; L776-L823 HydrophobicContact CD1-CD1 4.5Å; C777-L823 WeakPolarHBondContact SG-CD2 3.49Å; V807-L823 HydrophobicContact CB-CD1 4.41Å; V807-L823 WeakPolarHBondContact O-CD1 3.28Å; L823-L828 HydrophobicContact CD2-CD2 3.74Å; L823-L828 HydrophobicContact CD2-CG 4.33Å
824K95.8Very high88.5Confident58 Ų5863.6 Ų63.625%0.25236%0.359SS..  trans-70141.2172.5-67.3175.9-170.4176.70111.3N805 K806 V807 A808 T809 E826 S827N805-K824 PolarHBondContact O-NZ 3.03Å; K806-K824 WeakPolarHBondContact O-CD 3.3Å; K806-K824 WeakPolarHBondContact O-CE 3.46Å; K806-K824 PolarHBondContact O-NZ 3.35Å; V807-K824 WeakPolarHBondContact O-CB 3.46Å; V807-K824 WeakPolarHBondContact O-CG 3.4Å; V807-K824 PolarHBondContact O-N 2.87Å; A808-K824 VanDerWaalsContact O-CE 3.23Å; A808-K824 WeakPolarHBondContact O-CE 3.38Å; T809-K824 HydrophobicContact CG2-CG 3.99Å; K824-E826 PolarHBondContact O-N 2.94Å; K824-E826 VanDerWaalsContact O-N 3.17Å; K824-S827 PolarHBondContact O-N 3.3Å
825D91.8Very high89.5Confident123 Ų12361 Ų6166%0.65833%0.331SS*.G310 helixtrans-57.3-33.5177.2-62.9-32.6000113S827 L828D825-S827 PolarHBondContact O-N 3.05Å; D825-L828 HydrophobicContact CB-CD1 4.38Å; D825-L828 WeakPolarHBondContact O-CB 3.37Å; D825-L828 PolarHBondContact O-N 2.95Å
826E92.6Very high90.5Very high155 Ų15554 Ų5472%0.72429%0.286SS*.G310 helixtrans-62.4-25.1176.7-64.7178.9-170.100113.9K824 K829K824-E826 PolarHBondContact O-N 2.94Å; K824-E826 VanDerWaalsContact O-N 3.17Å; E826-K829 VanDerWaalsContact O-CD 3.23Å; E826-K829 WeakPolarHBondContact O-CD 3.25Å; E826-K829 VanDerWaalsContact O-CE 3.24Å; E826-K829 WeakPolarHBondContact O-CE 3.46Å; E826-K829 WeakPolarHBondContact O-CG 3.39Å
827S93.9Very high92.3Very high12 Ų1249 Ų498%0.08425%0.249CC..G310 helixtrans-91.1-9.1-179.9-58.40000113.2K824 D825 K829 D830K824-S827 PolarHBondContact O-N 3.3Å; D825-S827 PolarHBondContact O-N 3.05Å; S827-K829 PolarHBondContact O-N 2.79Å; S827-D830 PolarHBondContact O-N 3.12Å
828L91.3Very high93.3Very high36 Ų3647.9 Ų47.919%0.18823%0.232CC..G310 helixtrans-66.7-22.7177.5-70.5167.6000113.3L823 D825 D830 F831L823-L828 HydrophobicContact CD2-CD2 3.74Å; L823-L828 HydrophobicContact CD2-CG 4.33Å; D825-L828 HydrophobicContact CB-CD1 4.38Å; D825-L828 WeakPolarHBondContact O-CB 3.37Å; D825-L828 PolarHBondContact O-N 2.95Å; L828-D830 PolarHBondContact O-N 2.98Å; L828-F831 WeakPolarHBondContact O-CB 3.42Å; L828-F831 PolarHBondContact O-N 2.95Å
829K91.3Very high93.9Very high146 Ų14642.3 Ų42.364%0.63521%0.212SC*.G310 helixtrans-63.8-20.3175.475.3-167.7176.5-169.60112.9E826 S827 P866E826-K829 VanDerWaalsContact O-CD 3.23Å; E826-K829 WeakPolarHBondContact O-CD 3.25Å; E826-K829 VanDerWaalsContact O-CE 3.24Å; E826-K829 WeakPolarHBondContact O-CE 3.46Å; E826-K829 WeakPolarHBondContact O-CG 3.39Å; S827-K829 PolarHBondContact O-N 2.79Å; K829-P866 WeakPolarHBondContact O-CB 3.4Å
830D93.6Very high93.9Very high46 Ų4647 Ų4725%0.24623%0.229CC..G310 helixtrans-99.10.1-174.2-52.4-54.5000112.2I773 S827 L828 N832I773-D830 HydrophobicContact CD1-CB 4.24Å; S827-D830 PolarHBondContact O-N 3.12Å; L828-D830 PolarHBondContact O-N 2.98Å; D830-N832 PolarHBondContact O-N 3Å
831F95.3Very high93.8Very high17 Ų1749.9 Ų49.98%0.07525%0.246CC..  trans-65.6124.4175.5170.5-105.6000111.7C777 L828 M833 Y838 A846 Q850 L863 P866C777-F831 HydrophobicContact CB-CD2 3.73Å; C777-F831 HydrophobicContact CB-CE2 4.01Å; C777-F831 VanDerWaalsContact SG-CD2 3.57Å; L828-F831 WeakPolarHBondContact O-CB 3.42Å; L828-F831 PolarHBondContact O-N 2.95Å; F831-M833 HydrophobicContact CE1-CB 4.28Å; F831-M833 HydrophobicContact CZ-CB 4.43Å; F831-Y838 HydrophobicContact CE2-CE2 4.21Å; F831-A846 HydrophobicContact CE2-CB 4.1Å; F831-A846 HydrophobicContact CZ-CB 4.22Å; F831-Q850 HydrophobicContact CD1-CG 4.06Å; F831-Q850 HydrophobicContact CD2-CG 4.47Å; F831-Q850 HydrophobicContact CE1-CB 4.19Å; F831-Q850 HydrophobicContact CE1-CG 3.74Å; F831-Q850 HydrophobicContact CE2-CG 4.16Å; F831-Q850 HydrophobicContact CG-CG 4.41Å; F831-Q850 HydrophobicContact CZ-CG 3.78Å; F831-L863 HydrophobicContact CE1-CD1 4.42Å; F831-L863 HydrophobicContact CE1-CD2 4.47Å; F831-P866 WeakPolarHBondContact O-CD 3.45Å
832N95.2Very high93.7Very high6 Ų650.7 Ų50.73%0.03225%0.251CS..  trans-104.4126.9168.2-173.113.9000109.9E753 R770 H774 D830 Y834 F835 P866 H916E753-N832 PolarHBondContact OE1-ND2 2.77Å; R770-N832 PolarHBondContact NH2-ND2 3.25Å; H774-N832 PolarHBondContact CD2-O 3.24Å; H774-N832 PolarHBondContact NE2-N 2.88Å; H774-N832 PolarHBondContact NE2-O 3.42Å; D830-N832 PolarHBondContact O-N 3Å; N832-Y834 PolarHBondContact ND2-O 3.46Å; N832-Y834 PolarHBondContact OD1-N 3.42Å; N832-F835 HydrophobicContact CB-CB 4.47Å; N832-F835 PolarHBondContact O-N 2.99Å; N832-P866 HydrophobicContact CB-CG 4.01Å; N832-H916 PolarHBondContact OD1-CE1 2.95Å; N832-H916 VanDerWaalsContact OD1-CE1 3.27Å
833M93.9Very high93.7Very high16 Ų1649 Ų498%0.07924%0.244CC..THydrogen-bonded Turntrans-63.2-46.6174.6-170.3170.980.100111.1F831 F835 H843 E847 L863F831-M833 HydrophobicContact CE1-CB 4.28Å; F831-M833 HydrophobicContact CZ-CB 4.43Å; M833-F835 VanDerWaalsContact C-N 3.28Å; M833-F835 PolarHBondContact O-N 2.86Å; M833-H843 PolarHBondContact O-CD2 3.38Å; M833-H843 PolarHBondContact O-NE2 3.35Å; M833-E847 HydrophobicContact SD-CG 4.03Å; M833-L863 HydrophobicContact CG-CD1 4.46Å; M833-L863 HydrophobicContact SD-CB 3.94Å; M833-L863 HydrophobicContact SD-CD1 3.79Å
834Y95.1Very high93.6Very high2 Ų251.8 Ų51.81%0.00826%0.264CS..THydrogen-bonded Turntrans-91.954176.2-62.6-67.5000111.3I748 Y749 N832 Y836 H843 Q912 M913 H916I748-Y834 HydrophobicContact CD1-CD2 3.78Å; I748-Y834 HydrophobicContact CD1-CE2 4.01Å; I748-Y834 HydrophobicContact CD1-CG 4.13Å; I748-Y834 HydrophobicContact CG2-CD2 4.47Å; I748-Y834 HydrophobicContact CG2-CG 4.42Å; Y749-Y834 WeakPolarHBondContact CE1-O 3.37Å; N832-Y834 PolarHBondContact ND2-O 3.46Å; N832-Y834 PolarHBondContact OD1-N 3.42Å; Y834-Y836 PolarHBondContact O-N 3.36Å; Y834-H843 AromaticContact CD1-NE2 3.39Å; Y834-H843 WeakPolarHBondContact CD1-NE2 3.45Å; Y834-H843 AromaticContact CE1-CE1 3.95Å; Y834-H843 AromaticContact CE1-NE2 3.34Å; Y834-H843 VanDerWaalsContact CE1-NE2 3.34Å; Y834-H843 WeakPolarHBondContact CE1-NE2 3.28Å; Y834-Q912 VanDerWaalsContact OH-C 3.29Å; Y834-Q912 WeakPolarHBondContact OH-CB 3.5Å; Y834-M913 HydrophobicContact CE1-CE 3.94Å; Y834-M913 HydrophobicContact CE1-CG 3.72Å; Y834-M913 HydrophobicContact CE2-CG 4.22Å; Y834-M913 WeakPolarHBondContact OH-CG 3.42Å; Y834-M913 PolarHBondContact OH-N 3.45Å; Y834-H916 HydrophobicContact CD2-CB 3.91Å; Y834-H916 AromaticContact CD2-CD2 3.84Å; Y834-H916 AromaticContact CD2-CE1 3.8Å; Y834-H916 AromaticContact CD2-CG 3.52Å; Y834-H916 AromaticContact CD2-ND1 3.51Å; Y834-H916 HydrophobicContact CE2-CB 3.65Å; Y834-H916 AromaticContact CE2-CG 3.78Å; Y834-H916 AromaticContact CE2-ND1 3.9Å
835F96.1Very high93.6Very high6 Ų654.6 Ų54.63%0.02628%0.276CS..  trans-70.6119.3168.8175.2-122.3000109.9R770 H774 N832 M833 H837 Y838R770-F835 HydrophobicContact CG-CD2 4.4Å; R770-F835 HydrophobicContact CG-CE2 3.97Å; H774-F835 HydrophobicContact CB-CB 4.49Å; H774-F835 HydrophobicContact CB-CD1 3.33Å; H774-F835 HydrophobicContact CB-CE1 3.54Å; H774-F835 HydrophobicContact CB-CG 3.91Å; H774-F835 HydrophobicContact CB-CZ 4.3Å; H774-F835 WeakPolarHBondContact CD2-CB 3.43Å; H774-F835 AromaticContact CD2-CD1 3.87Å; H774-F835 AromaticContact CD2-CG 3.53Å; H774-F835 AromaticContact CG-CD1 3.48Å; H774-F835 VanDerWaalsContact CG-CD1 3.48Å; H774-F835 AromaticContact CG-CD2 3.97Å; H774-F835 AromaticContact CG-CE1 3.94Å; H774-F835 AromaticContact CG-CG 3.48Å; H774-F835 VanDerWaalsContact CG-CG 3.48Å; H774-F835 AromaticContact ND1-CD2 3.97Å; H774-F835 AromaticContact ND1-CG 3.96Å; N832-F835 HydrophobicContact CB-CB 4.47Å; N832-F835 PolarHBondContact O-N 2.99Å; M833-F835 VanDerWaalsContact C-N 3.28Å; M833-F835 PolarHBondContact O-N 2.86Å; F835-H837 HydrophobicContact CD1-CB 4.31Å; F835-H837 HydrophobicContact CE1-CB 3.67Å; F835-H837 HydrophobicContact CZ-CB 3.8Å; F835-H837 AromaticContact CZ-ND1 3.62Å; F835-H837 PolarHBondContact O-N 3.26Å; F835-H837 VanDerWaalsContact O-N 3.09Å; F835-Y838 HydrophobicContact CB-CD2 3.88Å; F835-Y838 HydrophobicContact CB-CE2 3.91Å; F835-Y838 HydrophobicContact CB-CG 4.37Å; F835-Y838 AromaticContact CD1-CD1 3.88Å; F835-Y838 HydrophobicContact CD1-CD1 3.88Å; F835-Y838 HydrophobicContact CD1-CD2 4.38Å; F835-Y838 AromaticContact CD1-CE1 3.95Å; F835-Y838 HydrophobicContact CD1-CE1 3.95Å; F835-Y838 HydrophobicContact CD1-CE2 4.44Å; F835-Y838 HydrophobicContact CD1-CG 4.12Å; F835-Y838 WeakPolarHBondContact O-CB 3.49Å; F835-Y838 PolarHBondContact O-N 3.08Å
836Y93.3Very high93.8Very high17 Ų1748.8 Ų48.87%0.06725%0.245CC..THydrogen-bonded Turntrans-63.8-17.2-166.874.6-61.1000116.5Y688 D689 E753 Y834Y688-Y836 HydrophobicContact CD1-CD2 4.26Å; Y688-Y836 AromaticContact CE1-CD2 3.79Å; Y688-Y836 HydrophobicContact CE1-CD2 3.79Å; D689-Y836 VanDerWaalsContact OD2-CE2 3.28Å; D689-Y836 WeakPolarHBondContact OD2-CE2 3.35Å; D689-Y836 PolarHBondContact OD2-OH 3.21Å; E753-Y836 HydrophobicContact CB-CD1 4.11Å; E753-Y836 HydrophobicContact CB-CE1 4.24Å; E753-Y836 HydrophobicContact CB-CG 4.48Å; E753-Y836 HydrophobicContact CG-CD1 3.44Å; E753-Y836 VanDerWaalsContact CG-CD1 3.44Å; E753-Y836 HydrophobicContact CG-CE1 4.04Å; E753-Y836 HydrophobicContact CG-CG 3.81Å; Y834-Y836 PolarHBondContact O-N 3.36Å
837H95.4Very high93.9Very high22 Ų2242.9 Ų42.910%0.10222%0.218CC..THydrogen-bonded Turntrans-92.34174.1-60.4148.5000114.7R684 D689 E771 F835 S839R684-H837 VanDerWaalsContact CD-CD2 3.48Å; R684-H837 WeakPolarHBondContact CD-CD2 3.31Å; R684-H837 PolarHBondContact NE-CD2 3.14Å; R684-H837 VanDerWaalsContact NE-CD2 3.32Å; R684-H837 PolarHBondContact NE-ND1 2.86Å; R684-H837 PolarHBondContact NH2-ND1 2.95Å; R684-H837 VanDerWaalsContact NH2-ND1 3.14Å; D689-H837 IonicContact OD1-CD2 3.75Å; D689-H837 IonicContact OD1-NE2 3.62Å; D689-H837 PolarHBondContact OD1-NE2 2.74Å; D689-H837 IonicContact OD2-CE1 3.5Å; D689-H837 PolarHBondContact OD2-CE1 3.25Å; D689-H837 IonicContact OD2-NE2 2.78Å; D689-H837 PolarHBondContact OD2-NE2 2.83Å; E771-H837 IonicContact OE1-CE1 3.92Å; E771-H837 PolarHBondContact OE1-CE1 3.33Å; E771-H837 IonicContact OE1-ND1 2.85Å; E771-H837 PolarHBondContact OE1-ND1 3.24Å; E771-H837 IonicContact OE2-ND1 2.83Å; F835-H837 HydrophobicContact CD1-CB 4.31Å; F835-H837 HydrophobicContact CE1-CB 3.67Å; F835-H837 HydrophobicContact CZ-CB 3.8Å; F835-H837 AromaticContact CZ-ND1 3.62Å; F835-H837 PolarHBondContact O-N 3.26Å; F835-H837 VanDerWaalsContact O-N 3.09Å; H837-S839 PolarHBondContact O-N 3.36Å
838Y94.7Very high93.9Very high18 Ų1848.1 Ų48.17%0.07124%0.24CC..  trans-74.2123.5168.1-74-28.4000111.3H774 I778 F831 F835 Q842 H843 A846H774-Y838 WeakPolarHBondContact CA-OH 3.4Å; H774-Y838 HydrophobicContact CB-CE1 3.87Å; H774-Y838 WeakPolarHBondContact CB-OH 3.33Å; H774-Y838 WeakPolarHBondContact O-CE1 3.35Å; H774-Y838 PolarHBondContact O-OH 3.44Å; I778-Y838 HydrophobicContact CD1-CD1 4.26Å; I778-Y838 HydrophobicContact CD1-CE1 3.74Å; I778-Y838 HydrophobicContact CG1-CE1 4.11Å; F831-Y838 HydrophobicContact CE2-CE2 4.21Å; F835-Y838 HydrophobicContact CB-CD2 3.88Å; F835-Y838 HydrophobicContact CB-CE2 3.91Å; F835-Y838 HydrophobicContact CB-CG 4.37Å; F835-Y838 AromaticContact CD1-CD1 3.88Å; F835-Y838 HydrophobicContact CD1-CD1 3.88Å; F835-Y838 HydrophobicContact CD1-CD2 4.38Å; F835-Y838 AromaticContact CD1-CE1 3.95Å; F835-Y838 HydrophobicContact CD1-CE1 3.95Å; F835-Y838 HydrophobicContact CD1-CE2 4.44Å; F835-Y838 HydrophobicContact CD1-CG 4.12Å; F835-Y838 WeakPolarHBondContact O-CB 3.49Å; F835-Y838 PolarHBondContact O-N 3.08Å; Y838-Q842 HydrophobicContact CD1-CB 3.85Å; Y838-Q842 HydrophobicContact CG-CB 4.18Å; Y838-H843 HydrophobicContact CD2-CB 4.48Å; Y838-A846 HydrophobicContact CE2-CB 3.72Å
839S91.8Very high94Very high53 Ų5349.4 Ų49.437%0.37125%0.246SC..  trans-60.5157.9157.168.60000110.4H837 T841 Q842 H843H837-S839 PolarHBondContact O-N 3.36Å; S839-T841 PolarHBondContact O-N 3.06Å; S839-T841 VanDerWaalsContact O-N 3.07Å; S839-T841 PolarHBondContact OG-OG1 3.01Å; S839-Q842 VanDerWaalsContact CB-OE1 3.3Å; S839-Q842 WeakPolarHBondContact O-CA 3.44Å; S839-Q842 WeakPolarHBondContact O-CB 3.45Å; S839-Q842 PolarHBondContact O-N 2.67Å; S839-Q842 WeakPolarHBondContact OG-CG 3.5Å; S839-Q842 PolarHBondContact OG-N 3.11Å; S839-Q842 PolarHBondContact OG-OE1 2.89Å; S839-H843 PolarHBondContact O-N 3.37Å
840K88.8Confident94.2Very high114 Ų11443 Ų4350%0.49622%0.219SC..Hα-helixtrans-52-36.8179.3-64.6-174.1175.5-111.50113.2V660 E742 S844V660-K840 VanDerWaalsContact CG1-NZ 3.27Å; E742-K840 IonicContact OE1-NZ 3.33Å; E742-K840 PolarHBondContact OE1-NZ 3.37Å; K840-S844 PolarHBondContact O-N 3.45Å; K840-S844 PolarHBondContact O-OG 3.24Å
841T92.5Very high94.1Very high96 Ų9642.3 Ų42.359%0.58921%0.214SC*.Hα-helixtrans-71.7-34.7177.3710000113.3S839 K845S839-T841 PolarHBondContact O-N 3.06Å; S839-T841 VanDerWaalsContact O-N 3.07Å; S839-T841 PolarHBondContact OG-OG1 3.01Å; T841-K845 WeakPolarHBondContact O-CB 3.48Å; T841-K845 VanDerWaalsContact O-CG 3.27Å; T841-K845 WeakPolarHBondContact O-CG 3.36Å; T841-K845 PolarHBondContact O-N 3.08Å
842Q94.9Very high94Very high45 Ų4546.3 Ų46.321%0.2123%0.231CC..Hα-helixtrans-71.7-41.3175.8-72.5163.9-5600111I778 Y838 S839 K845 A846I778-Q842 HydrophobicContact CD1-CB 3.84Å; I778-Q842 HydrophobicContact CD1-CG 3.87Å; Y838-Q842 HydrophobicContact CD1-CB 3.85Å; Y838-Q842 HydrophobicContact CG-CB 4.18Å; S839-Q842 VanDerWaalsContact CB-OE1 3.3Å; S839-Q842 WeakPolarHBondContact O-CA 3.44Å; S839-Q842 WeakPolarHBondContact O-CB 3.45Å; S839-Q842 PolarHBondContact O-N 2.67Å; S839-Q842 WeakPolarHBondContact OG-CG 3.5Å; S839-Q842 PolarHBondContact OG-N 3.11Å; S839-Q842 PolarHBondContact OG-OE1 2.89Å; Q842-K845 PolarHBondContact O-N 3.29Å; Q842-A846 WeakPolarHBondContact O-CB 3.28Å; Q842-A846 PolarHBondContact O-N 3.01Å
843H94.5Very high93.7Very high27 Ų2748.9 Ų48.913%0.12524%0.24CC..Hα-helixtrans-54.7-55.1175.1178.9-85.5000111.5M833 Y834 Y838 S839 K845 A846 E847M833-H843 PolarHBondContact O-CD2 3.38Å; M833-H843 PolarHBondContact O-NE2 3.35Å; Y834-H843 AromaticContact CD1-NE2 3.39Å; Y834-H843 WeakPolarHBondContact CD1-NE2 3.45Å; Y834-H843 AromaticContact CE1-CE1 3.95Å; Y834-H843 AromaticContact CE1-NE2 3.34Å; Y834-H843 VanDerWaalsContact CE1-NE2 3.34Å; Y834-H843 WeakPolarHBondContact CE1-NE2 3.28Å; Y838-H843 HydrophobicContact CD2-CB 4.48Å; S839-H843 PolarHBondContact O-N 3.37Å; H843-K845 VanDerWaalsContact C-N 3.32Å; H843-K845 PolarHBondContact O-N 2.88Å; H843-A846 PolarHBondContact O-N 2.93Å; H843-E847 PolarHBondContact O-N 3.46Å
844S94.4Very high93.6Very high72 Ų7251.1 Ų51.150%0.50325%0.248SC..Hα-helixtrans-62.9-34.7178.7-590000113.5K840 H848K840-S844 PolarHBondContact O-N 3.45Å; K840-S844 PolarHBondContact O-OG 3.24Å; S844-H848 WeakPolarHBondContact O-CB 3.26Å; S844-H848 PolarHBondContact O-N 3.23Å; S844-H848 VanDerWaalsContact O-N 3.14Å
845K95.8Very high93.4Very high117 Ų11757.2 Ų57.251%0.50927%0.274SS..Hα-helixtrans-67.2-45.3174.4-77.1176.6176.2-172.70111.8I778 T841 Q842 H843 H848 M849I778-K845 HydrophobicContact CG2-CB 4.04Å; I778-K845 HydrophobicContact CG2-CD 4.23Å; T841-K845 WeakPolarHBondContact O-CB 3.48Å; T841-K845 VanDerWaalsContact O-CG 3.27Å; T841-K845 WeakPolarHBondContact O-CG 3.36Å; T841-K845 PolarHBondContact O-N 3.08Å; Q842-K845 PolarHBondContact O-N 3.29Å; H843-K845 VanDerWaalsContact C-N 3.32Å; H843-K845 PolarHBondContact O-N 2.88Å; K845-H848 PolarHBondContact O-N 2.91Å; K845-M849 WeakPolarHBondContact O-CB 3.31Å; K845-M849 PolarHBondContact O-N 3.37Å
846A95.4Very high93.2Very high1 Ų163.5 Ų63.51%0.00830%0.304CS..Hα-helixtrans-62.2-49.7178.800000110.9I778 F831 Y838 Q842 H843 H848 M849 Q850I778-A846 HydrophobicContact CG1-CB 4.12Å; F831-A846 HydrophobicContact CE2-CB 4.1Å; F831-A846 HydrophobicContact CZ-CB 4.22Å; Y838-A846 HydrophobicContact CE2-CB 3.72Å; Q842-A846 WeakPolarHBondContact O-CB 3.28Å; Q842-A846 PolarHBondContact O-N 3.01Å; H843-A846 PolarHBondContact O-N 2.93Å; A846-H848 PolarHBondContact O-N 3.22Å; A846-M849 PolarHBondContact O-N 3.5Å; A846-Q850 WeakPolarHBondContact O-CG 3.06Å; A846-Q850 PolarHBondContact O-N 3.48Å
847E94.6Very high93.1Very high32 Ų3266.4 Ų66.415%0.1532%0.318CS..Hα-helixtrans-53.8-52175.9-170.4-158.4165.200111.4M833 H843 M849 Q850 K851 L863M833-E847 HydrophobicContact SD-CG 4.03Å; H843-E847 PolarHBondContact O-N 3.46Å; E847-M849 PolarHBondContact O-N 3.13Å; E847-Q850 PolarHBondContact O-N 3Å; E847-K851 HydrophobicContact CG-CD 4.28Å; E847-K851 PolarHBondContact O-N 3.47Å; E847-K851 WeakPolarHBondContact OE1-CE 3.3Å; E847-K851 IonicContact OE1-NZ 3.97Å; E847-K851 PolarHBondContact OE1-NZ 3.5Å; E847-L863 HydrophobicContact CG-CD1 3.88Å
848H94.4Very high92.8Very high121 Ų12172.8 Ų72.856%0.5635%0.353SS*.Hα-helixtrans-60.5-43.8179.8-179.575.3000112.3S844 K845 A846 K852S844-H848 WeakPolarHBondContact O-CB 3.26Å; S844-H848 PolarHBondContact O-N 3.23Å; S844-H848 VanDerWaalsContact O-N 3.14Å; K845-H848 PolarHBondContact O-N 2.91Å; A846-H848 PolarHBondContact O-N 3.22Å; H848-K852 WeakPolarHBondContact O-CB 3.42Å; H848-K852 PolarHBondContact O-N 2.97Å
849M93.9Very high92.5Very high64 Ų6477.6 Ų77.632%0.31537%0.374SS..Hα-helixtrans-64.2-42.5-179.8-171.36072.700111.9I778 K845 A846 E847 R853I778-M849 WeakPolarHBondContact O-CE 3.41Å; K845-M849 WeakPolarHBondContact O-CB 3.31Å; K845-M849 PolarHBondContact O-N 3.37Å; A846-M849 PolarHBondContact O-N 3.5Å; E847-M849 PolarHBondContact O-N 3.13Å; M849-R853 WeakPolarHBondContact O-CB 3.44Å; M849-R853 PolarHBondContact O-N 2.93Å
850Q93.8Very high92.4Very high11 Ų1178.6 Ų78.65%0.05138%0.375CS..Hα-helixtrans-73.2-39.8-178.8-61.8-53-3800112.5C777 F831 A846 E847 R853 R854 L863C777-Q850 PolarHBondContact O-NE2 2.92Å; F831-Q850 HydrophobicContact CD1-CG 4.06Å; F831-Q850 HydrophobicContact CD2-CG 4.47Å; F831-Q850 HydrophobicContact CE1-CB 4.19Å; F831-Q850 HydrophobicContact CE1-CG 3.74Å; F831-Q850 HydrophobicContact CE2-CG 4.16Å; F831-Q850 HydrophobicContact CG-CG 4.41Å; F831-Q850 HydrophobicContact CZ-CG 3.78Å; A846-Q850 WeakPolarHBondContact O-CG 3.06Å; A846-Q850 PolarHBondContact O-N 3.48Å; E847-Q850 PolarHBondContact O-N 3Å; Q850-R853 PolarHBondContact O-N 2.98Å; Q850-R854 WeakPolarHBondContact O-CG 3.4Å; Q850-R854 PolarHBondContact O-N 3.41Å; Q850-L863 HydrophobicContact CB-CD1 4.37Å; Q850-L863 HydrophobicContact CB-CD2 3.89Å
851K92.4Very high92.5Very high32 Ų3276 Ų7614%0.13937%0.365CS..Hα-helixtrans-60.4-46.7170.7-75.5-177.9171.8173.40111.5E847 R853 R854 K855 E861 L863E847-K851 HydrophobicContact CG-CD 4.28Å; E847-K851 PolarHBondContact O-N 3.47Å; E847-K851 WeakPolarHBondContact OE1-CE 3.3Å; E847-K851 IonicContact OE1-NZ 3.97Å; E847-K851 PolarHBondContact OE1-NZ 3.5Å; K851-R853 VanDerWaalsContact C-N 3.34Å; K851-R853 PolarHBondContact O-N 3.11Å; K851-R854 PolarHBondContact O-N 2.7Å; K851-K855 WeakPolarHBondContact O-CB 3.43Å; K851-K855 PolarHBondContact O-N 3.35Å; K851-E861 HydrophobicContact CG-CB 4.32Å; K851-L863 HydrophobicContact CG-CD1 4.02Å; K851-L863 HydrophobicContact CG-CG 4.34Å
852K92.8Very high92.4Very high100 Ų10071.5 Ų71.544%0.43534%0.337SS..Hα-helixtrans-57.8-42.9176.4-178.5-179.1178.4-177.20112.4H848 Q856H848-K852 WeakPolarHBondContact O-CB 3.42Å; H848-K852 PolarHBondContact O-N 2.97Å; K852-Q856 WeakPolarHBondContact O-CG 3.41Å; K852-Q856 PolarHBondContact O-N 3.47Å; K852-Q856 VanDerWaalsContact O-N 3.13Å
853R90.1Very high92.3Very high60 Ų6070 Ų7023%0.22633%0.331CS..Hα-helixtrans-63.7-50.8176.9-174.2-179.5-58.3-155.84.6111.8M849 Q850 K851 K855 Q856 E857M849-R853 WeakPolarHBondContact O-CB 3.44Å; M849-R853 PolarHBondContact O-N 2.93Å; Q850-R853 PolarHBondContact O-N 2.98Å; K851-R853 VanDerWaalsContact C-N 3.34Å; K851-R853 PolarHBondContact O-N 3.11Å; R853-K855 VanDerWaalsContact C-N 3.29Å; R853-K855 PolarHBondContact O-N 2.95Å; R853-Q856 WeakPolarHBondContact O-CB 3.43Å; R853-Q856 PolarHBondContact O-N 3.37Å; R853-E857 WeakPolarHBondContact CG-OE1 3.45Å; R853-E857 PolarHBondContact O-N 3.46Å
854R90.6Very high92.3Very high63 Ų6370 Ų7024%0.23833%0.333CS..Hα-helixtrans-55.9-42.9177.1-78.3167.4158.9-95.57.3112.6Q850 K851 Q856 E857 N858 K859 D860 A862Q850-R854 WeakPolarHBondContact O-CG 3.4Å; Q850-R854 PolarHBondContact O-N 3.41Å; K851-R854 PolarHBondContact O-N 2.7Å; R854-Q856 PolarHBondContact O-N 3.13Å; R854-E857 CarbonylContact O-C 3.54Å; R854-E857 PolarHBondContact O-N 3.26Å; R854-E857 VanDerWaalsContact O-N 3.15Å; R854-N858 PolarHBondContact O-N 2.88Å; R854-K859 HydrophobicContact CB-CB 4.29Å; R854-K859 PolarHBondContact O-N 2.92Å; R854-D860 WeakPolarHBondContact CB-O 3.38Å; R854-D860 WeakPolarHBondContact CD-O 3.23Å; R854-D860 PolarHBondContact NH1-O 3.07Å; R854-D860 IonicContact NH1-OD1 2.71Å; R854-D860 PolarHBondContact NH1-OD1 3.13Å; R854-D860 IonicContact NH1-OD2 3.74Å; R854-A862 PolarHBondContact NE-O 3.32Å; R854-A862 PolarHBondContact NH1-O 3.38Å; R854-A862 PolarHBondContact NH2-O 3.38Å
855K91.1Very high92.2Very high131 Ų13166.9 Ų66.957%0.5731%0.311SS*.Hα-helixtrans-60.9-40.6175.1-161.8-172.3-159.694.20112.7K851 R853 E857 N858 E861K851-K855 WeakPolarHBondContact O-CB 3.43Å; K851-K855 PolarHBondContact O-N 3.35Å; R853-K855 VanDerWaalsContact C-N 3.29Å; R853-K855 PolarHBondContact O-N 2.95Å; K855-E857 VanDerWaalsContact C-N 3.31Å; K855-N858 PolarHBondContact O-N 3.37Å; K855-E861 IonicContact NZ-OE1 2.71Å; K855-E861 PolarHBondContact NZ-OE1 3.08Å
856Q91.8Very high92.1Very high137 Ų13761.9 Ų61.964%0.6429%0.291SS*.Hα-helixtrans-67.2-31.3175.1-72173.1-21.500112.7K852 R853 R854 N858K852-Q856 WeakPolarHBondContact O-CG 3.41Å; K852-Q856 PolarHBondContact O-N 3.47Å; K852-Q856 VanDerWaalsContact O-N 3.13Å; R853-Q856 WeakPolarHBondContact O-CB 3.43Å; R853-Q856 PolarHBondContact O-N 3.37Å; R854-Q856 PolarHBondContact O-N 3.13Å; Q856-N858 VanDerWaalsContact C-N 3.28Å; Q856-N858 PolarHBondContact O-N 2.81Å
857E90.9Very high91.8Very high79 Ų7965.8 Ų65.837%0.36932%0.316SS..THydrogen-bonded Turntrans-81.90.6175.8-67.5174.6-155.900113.9R853 R854 K855 K859R853-E857 WeakPolarHBondContact CG-OE1 3.45Å; R853-E857 PolarHBondContact O-N 3.46Å; R854-E857 CarbonylContact O-C 3.54Å; R854-E857 PolarHBondContact O-N 3.26Å; R854-E857 VanDerWaalsContact O-N 3.15Å; K855-E857 VanDerWaalsContact C-N 3.31Å; E857-K859 VanDerWaalsContact C-N 3.27Å; E857-K859 HydrophobicContact CB-CD 4.13Å; E857-K859 HydrophobicContact CB-CG 4.15Å; E857-K859 PolarHBondContact O-N 2.78Å; E857-K859 WeakPolarHBondContact OE2-CD 3.47Å; E857-K859 WeakPolarHBondContact OE2-CE 3.39Å; E857-K859 IonicContact OE2-NZ 2.75Å; E857-K859 PolarHBondContact OE2-NZ 3.32Å
858N90.1Very high91.6Very high155 Ų15564.9 Ų64.983%0.82931%0.313SS*.THydrogen-bonded Turntrans56.236.5-171.4-54.5-79.8000113.6R854 K855 Q856R854-N858 PolarHBondContact O-N 2.88Å; K855-N858 PolarHBondContact O-N 3.37Å; Q856-N858 VanDerWaalsContact C-N 3.28Å; Q856-N858 PolarHBondContact O-N 2.81Å
859K87.8Confident91.6Very high119 Ų11960.1 Ų60.152%0.51729%0.292SS..  trans-100.1165.2171.8-65.8175.3-179.4166.90110.8R854 E857R854-K859 HydrophobicContact CB-CB 4.29Å; R854-K859 PolarHBondContact O-N 2.92Å; E857-K859 VanDerWaalsContact C-N 3.27Å; E857-K859 HydrophobicContact CB-CD 4.13Å; E857-K859 HydrophobicContact CB-CG 4.15Å; E857-K859 PolarHBondContact O-N 2.78Å; E857-K859 WeakPolarHBondContact OE2-CD 3.47Å; E857-K859 WeakPolarHBondContact OE2-CE 3.39Å; E857-K859 IonicContact OE2-NZ 2.75Å; E857-K859 PolarHBondContact OE2-NZ 3.32Å
860D89.8Confident91.6Very high75 Ų7561.6 Ų61.640%0.40130%0.299SS..  trans-58.4148.2167.756.794.3000112R854 A862 D973R854-D860 WeakPolarHBondContact CB-O 3.38Å; R854-D860 WeakPolarHBondContact CD-O 3.23Å; R854-D860 PolarHBondContact NH1-O 3.07Å; R854-D860 IonicContact NH1-OD1 2.71Å; R854-D860 PolarHBondContact NH1-OD1 3.13Å; R854-D860 IonicContact NH1-OD2 3.74Å; D860-A862 PolarHBondContact O-N 3.3Å; D860-A862 WeakPolarHBondContact OD1-CB 3.37Å; D860-A862 PolarHBondContact OD1-N 2.93Å; D860-D973 WeakPolarHBondContact CA-OD2 3.37Å; D860-D973 HydrophobicContact CB-CB 4.22Å
861E90Very high91.7Very high59 Ų5962.1 Ų62.128%0.27630%0.301SS..  trans-84.810.5178.9-64-169.3-146.300112.7K851 K855 D973K851-E861 HydrophobicContact CG-CB 4.32Å; K855-E861 IonicContact NZ-OE1 2.71Å; K855-E861 PolarHBondContact NZ-OE1 3.08Å; E861-D973 PolarHBondContact N-OD2 2.93Å
862A91.3Very high91.9Very high1 Ų161.5 Ų61.51%0.00830%0.3CS..  trans-69.1135.3178.100000112R854 D860 P864 D973 M974 W977R854-A862 PolarHBondContact NE-O 3.32Å; R854-A862 PolarHBondContact NH1-O 3.38Å; R854-A862 PolarHBondContact NH2-O 3.38Å; D860-A862 PolarHBondContact O-N 3.3Å; D860-A862 WeakPolarHBondContact OD1-CB 3.37Å; D860-A862 PolarHBondContact OD1-N 2.93Å; A862-P864 WeakPolarHBondContact O-CD 3.47Å; A862-D973 HydrophobicContact CB-CB 4.06Å; A862-M974 HydrophobicContact CB-CB 4.37Å; A862-M974 HydrophobicContact CB-SD 4.34Å; A862-W977 HydrophobicContact CB-CB 4.32Å
863L93.4Very high92Very high14 Ų1462.2 Ų62.27%0.07332%0.315CS..  trans-116.871.7176.4-61.9-179.2000110.3F831 M833 E847 Q850 K851F831-L863 HydrophobicContact CE1-CD1 4.42Å; F831-L863 HydrophobicContact CE1-CD2 4.47Å; M833-L863 HydrophobicContact CG-CD1 4.46Å; M833-L863 HydrophobicContact SD-CB 3.94Å; M833-L863 HydrophobicContact SD-CD1 3.79Å; E847-L863 HydrophobicContact CG-CD1 3.88Å; Q850-L863 HydrophobicContact CB-CD1 4.37Å; Q850-L863 HydrophobicContact CB-CD2 3.89Å; K851-L863 HydrophobicContact CG-CD1 4.02Å; K851-L863 HydrophobicContact CG-CG 4.34Å
864P92.9Very high92.3Very high26 Ų2660.5 Ų60.517%0.16931%0.314CS..PPolyproline II helixtrans-68.6153.617831-36.4000111.8A862 M974 W977A862-P864 WeakPolarHBondContact O-CD 3.47Å; P864-M974 HydrophobicContact CB-SD 4.47Å; P864-W977 HydrophobicContact CB-CD2 3.81Å; P864-W977 VanDerWaalsContact CB-CE2 3.5Å; P864-W977 HydrophobicContact CB-CE3 3.97Å; P864-W977 HydrophobicContact CB-CH2 3.59Å; P864-W977 HydrophobicContact CB-CZ2 3.38Å; P864-W977 HydrophobicContact CB-CZ3 3.9Å; P864-W977 HydrophobicContact CG-CD2 4.28Å; P864-W977 HydrophobicContact CG-CZ2 3.89Å
865P94.3Very high92.6Very high7 Ų757.5 Ų57.55%0.04530%0.302CS..PPolyproline II helixtrans-54.7141.7170.96-12.3000111.9H916 A919 L920 L923P865-H916 VanDerWaalsContact CB-CE1 3.43Å; P865-H916 WeakPolarHBondContact CB-CE1 2.82Å; P865-A919 HydrophobicContact CG-CB 3.53Å; P865-L920 HydrophobicContact CB-CD2 3.67Å; P865-L920 HydrophobicContact CB-CG 4.19Å; P865-L920 HydrophobicContact CG-CD2 3.97Å; P865-L920 HydrophobicContact CG-CG 4.01Å; P865-L923 HydrophobicContact CB-CD1 4.19Å; P865-L923 HydrophobicContact CG-CD1 3.97Å; P865-L923 WeakPolarHBondContact O-CD1 3.36Å
866P93.1Very high92.8Very high13 Ų1353.9 Ų53.98%0.08429%0.294CS..PPolyproline II helixtrans-67.2154.5167.631.3-33.8000109.4K829 F831 N832 P868K829-P866 WeakPolarHBondContact O-CB 3.4Å; F831-P866 WeakPolarHBondContact O-CD 3.45Å; N832-P866 HydrophobicContact CB-CG 4.01Å; P866-P868 VanDerWaalsContact O-CD 3.31Å; P866-P868 WeakPolarHBondContact O-CD 3.4Å; P866-P868 VanDerWaalsContact O-N 3.13Å
867P89.8Confident93Very high83 Ų8353.5 Ų53.554%0.53929%0.29SS..PPolyproline II helixtrans-56.5118.3174-22.834000110.3
868P88.8Confident93.3Very high12 Ų1249.7 Ų49.78%0.07827%0.272CS..PPolyproline II helixtrans-71.8151.4-178.929.4-35.4000110.7P866 Q927P866-P868 VanDerWaalsContact O-CD 3.31Å; P866-P868 WeakPolarHBondContact O-CD 3.4Å; P866-P868 VanDerWaalsContact O-N 3.13Å; P868-Q927 PolarHBondContact O-NE2 3.35Å
869P94.1Very high93.6Very high21 Ų2143.3 Ų43.314%0.13624%0.238CC..PPolyproline II helixtrans-56.4164167.9-24.533.9000112.5R754 Y755 V762R754-P869 HydrophobicContact CB-CB 4.33Å; R754-P869 HydrophobicContact CB-CG 4.45Å; R754-P869 WeakPolarHBondContact CD-O 3.21Å; R754-P869 PolarHBondContact NH1-O 3.23Å; Y755-P869 HydrophobicContact CD2-CG 4.03Å; Y755-P869 HydrophobicContact CE1-CG 4.07Å; Y755-P869 VanDerWaalsContact CE2-CD 3.46Å; Y755-P869 HydrophobicContact CE2-CG 3.53Å; Y755-P869 HydrophobicContact CG-CG 4.49Å; V762-P869 HydrophobicContact CG1-CB 3.85Å; V762-P869 HydrophobicContact CG1-CG 3.77Å
870E94.4Very high94Very high96 Ų9640.8 Ų40.845%0.44923%0.23SC..PPolyproline II helixtrans-71.6142.7169.5-67.3-178.116300110.5G760 N761 K931G760-E870 CarbonylContact C-O 3.59Å; G760-E870 VanDerWaalsContact CA-O 3.25Å; G760-E870 WeakPolarHBondContact CA-O 3.43Å; N761-E870 PolarHBondContact N-O 3.32Å; E870-K931 IonicContact OE1-NZ 3.37Å; E870-K931 PolarHBondContact OE1-NZ 3.06Å
871F96.6Very high94.4Very high22 Ų2237.3 Ų37.310%0.09621%0.211CC..BIsolated β-bridgetrans-68.8145166.9-80.9-69.7000110.3R754 V759 F875 V878 I879R754-F871 HydrophobicContact CG-CD1 4.07Å; R754-F871 HydrophobicContact CG-CE1 3.67Å; R754-F871 HydrophobicContact CG-CE2 4.24Å; R754-F871 HydrophobicContact CG-CZ 3.75Å; V759-F871 HydrophobicContact CG1-CD1 4.15Å; V759-F871 HydrophobicContact CG1-CE1 4.04Å; F871-F875 HydrophobicContact CB-CB 4.15Å; F871-F875 HydrophobicContact CD1-CB 3.56Å; F871-F875 HydrophobicContact CE1-CB 4.25Å; F871-F875 HydrophobicContact CG-CB 4.14Å; F871-V878 HydrophobicContact CE1-CB 4.25Å; F871-V878 HydrophobicContact CE1-CG1 4.4Å; F871-V878 HydrophobicContact CE1-CG2 4.46Å; F871-V878 HydrophobicContact CE2-CB 3.91Å; F871-V878 HydrophobicContact CE2-CG1 4.13Å; F871-V878 HydrophobicContact CZ-CB 3.74Å; F871-V878 HydrophobicContact CZ-CG1 3.67Å; F871-V878 HydrophobicContact CZ-CG2 4.41Å; F871-I879 HydrophobicContact CD2-CG2 3.79Å; F871-I879 HydrophobicContact CE2-CG2 3.74Å
872C96.6Very high94.7Very high19 Ų1934.6 Ų34.613%0.12820%0.199CC..PPolyproline II helixtrans-61.4155.1164.1-69.70000110.2G758 V759 G760 A874 F875 S876G758-C872 WeakPolarHBondContact O-CB 3.45Å; V759-C872 PolarHBondContact O-N 2.97Å; G760-C872 PolarHBondContact O-SG 3.45Å; G760-C872 VanDerWaalsContact O-SG 3.39Å; C872-A874 VanDerWaalsContact C-N 3.26Å; C872-A874 PolarHBondContact O-N 3.49Å; C872-F875 PolarHBondContact O-N 2.95Å; C872-S876 PolarHBondContact O-N 3.17Å
873P95.4Very high94.8Very high115 Ų11535.2 Ų35.275%0.74720%0.202SC*.G310 helixtrans-51.7-38.7-173.4-30.936.5000115.1F875 S876P873-F875 VanDerWaalsContact C-N 3.27Å; P873-F875 PolarHBondContact O-N 3.27Å; P873-S876 WeakPolarHBondContact O-CB 3.41Å; P873-S876 PolarHBondContact O-N 3.43Å; P873-S876 PolarHBondContact O-OG 3.02Å
874A95.4Very high94.9Very high23 Ų2334.7 Ų34.719%0.1920%0.199CC..G310 helixtrans-64.7-26.1177.900000114.3V628 S700 C872V628-A874 HydrophobicContact CB-CB 4.28Å; V628-A874 HydrophobicContact CG1-CB 4.15Å; V628-A874 HydrophobicContact CG2-CB 4.02Å; S700-A874 WeakPolarHBondContact CB-O 3.43Å; S700-A874 PolarHBondContact OG-O 2.97Å; C872-A874 VanDerWaalsContact C-N 3.26Å; C872-A874 PolarHBondContact O-N 3.49Å
875F97.4Very high95Very high0 Ų036.3 Ų36.30%021%0.207CC..G310 helixtrans-105-4.7-178.9-68.7-91.3000113.4H619 V620 Q696 I697 G758 V759 F871 C872 P873 K877 V878H619-F875 AromaticContact CD2-CZ 3.91Å; V620-F875 HydrophobicContact CG2-CZ 4.32Å; Q696-F875 HydrophobicContact CB-CD1 3.91Å; Q696-F875 HydrophobicContact CB-CE1 3.86Å; I697-F875 HydrophobicContact CG1-CE1 3.64Å; I697-F875 HydrophobicContact CG1-CZ 3.74Å; G758-F875 WeakPolarHBondContact O-CD2 3.36Å; G758-F875 VanDerWaalsContact O-CE2 3.32Å; G758-F875 WeakPolarHBondContact O-CE2 3.48Å; V759-F875 HydrophobicContact CB-CD2 4.49Å; V759-F875 HydrophobicContact CG1-CD1 4.1Å; V759-F875 HydrophobicContact CG1-CE1 4.38Å; V759-F875 HydrophobicContact CG1-CG 4.16Å; V759-F875 HydrophobicContact CG2-CE1 4.27Å; V759-F875 HydrophobicContact CG2-CE2 4.19Å; V759-F875 HydrophobicContact CG2-CZ 3.98Å; F871-F875 HydrophobicContact CB-CB 4.15Å; F871-F875 HydrophobicContact CD1-CB 3.56Å; F871-F875 HydrophobicContact CE1-CB 4.25Å; F871-F875 HydrophobicContact CG-CB 4.14Å; C872-F875 PolarHBondContact O-N 2.95Å; P873-F875 VanDerWaalsContact C-N 3.27Å; P873-F875 PolarHBondContact O-N 3.27Å; F875-K877 PolarHBondContact O-N 2.95Å; F875-V878 HydrophobicContact CB-CG2 4.46Å; F875-V878 HydrophobicContact CD1-CG2 4.46Å; F875-V878 WeakPolarHBondContact O-CB 3.44Å; F875-V878 VanDerWaalsContact O-CG2 3.25Å; F875-V878 WeakPolarHBondContact O-CG2 3.35Å; F875-V878 PolarHBondContact O-N 2.95Å
876S94.9Very high95.1Very high56 Ų5636 Ų3639%0.39221%0.205SC..G310 helixtrans-47.8-35.1-178.458.50000114.6C872 P873 V878 I879C872-S876 PolarHBondContact O-N 3.17Å; P873-S876 WeakPolarHBondContact O-CB 3.41Å; P873-S876 PolarHBondContact O-N 3.43Å; P873-S876 PolarHBondContact O-OG 3.02Å; S876-V878 VanDerWaalsContact C-N 3.31Å; S876-V878 PolarHBondContact O-N 3.26Å; S876-I879 WeakPolarHBondContact O-CG1 3.42Å
877K96.3Very high95.2Very high128 Ų12835.4 Ų35.456%0.55720%0.201SC*.G310 helixtrans-72.2-13.6-179-70.9177.8178.5177.10115.2S700 F875 I879 N880S700-K877 WeakPolarHBondContact O-CB 3.48Å; S700-K877 VanDerWaalsContact O-CD 3.3Å; S700-K877 WeakPolarHBondContact O-CD 3.38Å; F875-K877 PolarHBondContact O-N 2.95Å; K877-I879 PolarHBondContact O-N 3.27Å; K877-N880 VanDerWaalsContact O-CB 3.24Å; K877-N880 WeakPolarHBondContact O-CB 3.4Å; K877-N880 PolarHBondContact O-N 3.39Å; K877-N880 PolarHBondContact O-ND2 3.48Å
878V97.8Very high95.5Very high0 Ų031.9 Ų31.90%018%0.177CC..G310 helixtrans-58.3-32.4-179.4174.60000111.9Q696 A699 I750 V751 F871 F875 S876 N880 L881Q696-V878 HydrophobicContact CB-CG2 4.46Å; Q696-V878 VanDerWaalsContact O-CG2 3.3Å; Q696-V878 WeakPolarHBondContact O-CG2 3.36Å; A699-V878 HydrophobicContact CB-CG1 4.25Å; A699-V878 HydrophobicContact CB-CG2 4.09Å; I750-V878 HydrophobicContact CG2-CG1 3.92Å; I750-V878 WeakPolarHBondContact O-CG1 3.39Å; V751-V878 HydrophobicContact CG2-CG1 4.26Å; F871-V878 HydrophobicContact CE1-CB 4.25Å; F871-V878 HydrophobicContact CE1-CG1 4.4Å; F871-V878 HydrophobicContact CE1-CG2 4.46Å; F871-V878 HydrophobicContact CE2-CB 3.91Å; F871-V878 HydrophobicContact CE2-CG1 4.13Å; F871-V878 HydrophobicContact CZ-CB 3.74Å; F871-V878 HydrophobicContact CZ-CG1 3.67Å; F871-V878 HydrophobicContact CZ-CG2 4.41Å; F875-V878 HydrophobicContact CB-CG2 4.46Å; F875-V878 HydrophobicContact CD1-CG2 4.46Å; F875-V878 WeakPolarHBondContact O-CB 3.44Å; F875-V878 VanDerWaalsContact O-CG2 3.25Å; F875-V878 WeakPolarHBondContact O-CG2 3.35Å; F875-V878 PolarHBondContact O-N 2.95Å; S876-V878 VanDerWaalsContact C-N 3.31Å; S876-V878 PolarHBondContact O-N 3.26Å; V878-N880 PolarHBondContact O-N 3.19Å; V878-N880 VanDerWaalsContact O-N 3.08Å; V878-L881 WeakPolarHBondContact O-CB 3.43Å; V878-L881 WeakPolarHBondContact O-CG 3.34Å; V878-L881 PolarHBondContact O-N 3.21Å; V878-L881 VanDerWaalsContact O-N 3.09Å
879I96.3Very high95.7Very high21 Ų2133.7 Ų33.711%0.10818%0.183CC..G310 helixtrans-58-25.2177.369.9-177.6000113F871 S876 K877 L881 L882 E924 F939F871-I879 HydrophobicContact CD2-CG2 3.79Å; F871-I879 HydrophobicContact CE2-CG2 3.74Å; S876-I879 WeakPolarHBondContact O-CG1 3.42Å; K877-I879 PolarHBondContact O-N 3.27Å; I879-L881 PolarHBondContact O-N 2.89Å; I879-L881 VanDerWaalsContact O-N 3.14Å; I879-L882 WeakPolarHBondContact O-CB 3.39Å; I879-L882 PolarHBondContact O-N 2.83Å; I879-E924 HydrophobicContact CB-CG 4.31Å; I879-E924 HydrophobicContact CD1-CG 4.44Å; I879-E924 HydrophobicContact CG2-CG 4.16Å; I879-F939 HydrophobicContact CB-CE2 4.18Å; I879-F939 HydrophobicContact CD1-CD2 4.11Å; I879-F939 HydrophobicContact CD1-CE2 4.35Å; I879-F939 HydrophobicContact CG1-CD2 4.21Å; I879-F939 HydrophobicContact CG1-CE2 4.07Å; I879-F939 WeakPolarHBondContact O-CE2 3.21Å
880N96.6Very high95.7Very high66 Ų6632.8 Ų32.835%0.35318%0.177SC..G310 helixtrans-63.9-19.2179.7-63.7-42.7000112.8P704 K877 V878 L882 N883 C884P704-N880 HydrophobicContact CB-CB 4.37Å; P704-N880 HydrophobicContact CG-CB 4.21Å; K877-N880 VanDerWaalsContact O-CB 3.24Å; K877-N880 WeakPolarHBondContact O-CB 3.4Å; K877-N880 PolarHBondContact O-N 3.39Å; K877-N880 PolarHBondContact O-ND2 3.48Å; V878-N880 PolarHBondContact O-N 3.19Å; V878-N880 VanDerWaalsContact O-N 3.08Å; N880-L882 VanDerWaalsContact C-N 3.28Å; N880-L882 PolarHBondContact O-N 3.21Å; N880-N883 CarbonylContact O-C 3.5Å; N880-N883 PolarHBondContact O-N 3.46Å; N880-C884 PolarHBondContact O-N 2.84Å; N880-C884 VanDerWaalsContact O-N 3.15Å
881L97.4Very high95.8Very high1 Ų128.2 Ų28.21%0.00516%0.155CC..G310 helixtrans-59.6-36.8169.4-68.7-175.8000112.4A699 P704 F707 L708 I750 V751 V878 I879 N883 C884 M887A699-L881 HydrophobicContact CB-CD1 3.58Å; A699-L881 HydrophobicContact CB-CD2 4.42Å; A699-L881 HydrophobicContact CB-CG 4.07Å; P704-L881 HydrophobicContact CB-CD2 3.81Å; F707-L881 HydrophobicContact CB-CD2 4.22Å; F707-L881 HydrophobicContact CD1-CD1 4.07Å; F707-L881 HydrophobicContact CD1-CD2 3.58Å; F707-L881 HydrophobicContact CD1-CG 4.49Å; F707-L881 HydrophobicContact CE1-CD1 3.98Å; F707-L881 HydrophobicContact CE1-CD2 4.33Å; F707-L881 HydrophobicContact CG-CD2 4.18Å; L708-L881 HydrophobicContact CD2-CD2 4.18Å; L708-L881 HydrophobicContact CG-CD2 4.17Å; I750-L881 HydrophobicContact CG2-CD1 3.72Å; V751-L881 HydrophobicContact CG2-CB 4.23Å; V751-L881 HydrophobicContact CG2-CD1 4.22Å; V878-L881 WeakPolarHBondContact O-CB 3.43Å; V878-L881 WeakPolarHBondContact O-CG 3.34Å; V878-L881 PolarHBondContact O-N 3.21Å; V878-L881 VanDerWaalsContact O-N 3.09Å; I879-L881 PolarHBondContact O-N 2.89Å; I879-L881 VanDerWaalsContact O-N 3.14Å; L881-N883 PolarHBondContact O-N 2.87Å; L881-C884 PolarHBondContact O-SG 2.94Å; L881-M887 WeakPolarHBondContact O-CB 3.15Å; L881-M887 WeakPolarHBondContact O-CE 3.46Å; L881-M887 WeakPolarHBondContact O-CG 3.24Å
882L96.2Very high95.6Very high3 Ų328.3 Ų28.32%0.01616%0.155CC..THydrogen-bonded Turntrans-65.8-32.8177.5-62.1176.8000111.5V751 I879 N880 M887 I917 L920 F939 F941V751-L882 HydrophobicContact CB-CD2 4.42Å; V751-L882 HydrophobicContact CG1-CD1 3.68Å; V751-L882 HydrophobicContact CG1-CD2 3.99Å; V751-L882 HydrophobicContact CG1-CG 3.77Å; V751-L882 HydrophobicContact CG2-CD2 4.27Å; V751-L882 HydrophobicContact CG2-CG 4.42Å; I879-L882 WeakPolarHBondContact O-CB 3.39Å; I879-L882 PolarHBondContact O-N 2.83Å; N880-L882 VanDerWaalsContact C-N 3.28Å; N880-L882 PolarHBondContact O-N 3.21Å; L882-M887 WeakPolarHBondContact O-CG 3.43Å; L882-I917 HydrophobicContact CD2-CG2 3.84Å; L882-L920 HydrophobicContact CD1-CB 4.35Å; L882-F939 HydrophobicContact CB-CZ 4.18Å; L882-F939 HydrophobicContact CD1-CZ 4.43Å; L882-F941 HydrophobicContact CB-CD2 4.14Å; L882-F941 HydrophobicContact CB-CE2 4.17Å; L882-F941 WeakPolarHBondContact O-CD2 3.35Å; L882-F941 VanDerWaalsContact O-CE2 3.23Å; L882-F941 WeakPolarHBondContact O-CE2 3.3Å
883N93.9Very high95.4Very high13 Ų1328 Ų287%0.0715%0.153CC..THydrogen-bonded Turntrans-106.115.6-170.7-163.830.5000113.6N880 L881 F939 D940 F941 K944N880-N883 CarbonylContact O-C 3.5Å; N880-N883 PolarHBondContact O-N 3.46Å; L881-N883 PolarHBondContact O-N 2.87Å; N883-F939 HydrophobicContact CB-CD2 4.22Å; N883-F939 HydrophobicContact CB-CE2 3.67Å; N883-F939 HydrophobicContact CB-CZ 4.14Å; N883-D940 PolarHBondContact ND2-N 2.63Å; N883-D940 PolarHBondContact ND2-OD1 3.21Å; N883-F941 WeakPolarHBondContact OD1-CA 3.37Å; N883-K944 WeakPolarHBondContact O-CD 3.36Å; N883-K944 WeakPolarHBondContact O-CE 3.41Å; N883-K944 PolarHBondContact O-NZ 3.11Å; N883-K944 WeakPolarHBondContact OD1-CD 3.45Å; N883-K944 WeakPolarHBondContact OD1-CE 3.36Å; N883-K944 WeakPolarHBondContact OD1-CG 3.39Å
884C95.4Very high95.3Very high4 Ų422.6 Ų22.63%0.02712%0.118CC..SBendtrans-89.1162.817680.80000112.3P704 N705 L708 N880 L881 I886 M887 M888P704-C884 HydrophobicContact CB-CB 3.82Å; P704-C884 HydrophobicContact CG-CB 3.9Å; N705-C884 WeakPolarHBondContact OD1-CB 3.46Å; L708-C884 WeakPolarHBondContact CD1-SG 3.39Å; N880-C884 PolarHBondContact O-N 2.84Å; N880-C884 VanDerWaalsContact O-N 3.15Å; L881-C884 PolarHBondContact O-SG 2.94Å; C884-I886 VanDerWaalsContact C-N 3.35Å; C884-I886 PolarHBondContact O-N 3.04Å; C884-M887 PolarHBondContact O-N 3.15Å; C884-M887 PolarHBondContact SG-N 3.08Å; C884-M888 WeakPolarHBondContact O-CG 3.39Å; C884-M888 PolarHBondContact O-N 3.33Å
885D94.9Very high95.1Very high60 Ų6021.5 Ų21.532%0.32111%0.109SC..Hα-helixtrans-71.4-34.9-171.5-52.4-37.6000111H591 N705 M888 Y889 K944H591-D885 IonicContact CD2-OD2 2.92Å; H591-D885 IonicContact CE1-OD2 3.95Å; H591-D885 IonicContact NE2-OD2 2.63Å; H591-D885 PolarHBondContact NE2-OD2 2.96Å; N705-D885 PolarHBondContact OD1-N 3.16Å; D885-M888 PolarHBondContact O-N 3.05Å; D885-Y889 WeakPolarHBondContact O-CB 3.39Å; D885-Y889 PolarHBondContact O-N 3.31Å; D885-K944 IonicContact OD1-NZ 3.4Å
886I95.4Very high94.8Very high0 Ų024.2 Ų24.20%012%0.121CC..Hα-helixtrans-64.6-39.6175-59.2-64.3000111.5C589 N705 L708 L709 L712 C884 Y889 I890C589-I886 HydrophobicContact CB-CD1 3.93Å; N705-I886 HydrophobicContact CB-CG1 3.83Å; N705-I886 PolarHBondContact OD1-N 2.77Å; L708-I886 HydrophobicContact CB-CB 4.11Å; L708-I886 HydrophobicContact CB-CG2 3.57Å; L708-I886 HydrophobicContact CD1-CB 4.25Å; L708-I886 HydrophobicContact CD1-CG2 4.14Å; L709-I886 HydrophobicContact CD2-CD1 3.81Å; L709-I886 HydrophobicContact CD2-CG1 4.35Å; L709-I886 HydrophobicContact CG-CD1 4.2Å; L709-I886 HydrophobicContact CG-CG1 4.27Å; L712-I886 HydrophobicContact CD1-CG2 3.8Å; C884-I886 VanDerWaalsContact C-N 3.35Å; C884-I886 PolarHBondContact O-N 3.04Å; I886-Y889 PolarHBondContact O-N 3.4Å; I886-I890 HydrophobicContact CG2-CD1 4Å; I886-I890 HydrophobicContact CG2-CG1 4.48Å; I886-I890 VanDerWaalsContact O-CG1 3.3Å; I886-I890 WeakPolarHBondContact O-CG1 3.27Å; I886-I890 PolarHBondContact O-N 2.89Å
887M96.4Very high94.5Very high1 Ų123 Ų231%0.00511%0.108CC..Hα-helixtrans-63.2-47.1175179.562.777.600111.4L708 L747 L881 L882 C884 Y889 I890 L891 I917L708-M887 HydrophobicContact CD1-CB 3.77Å; L708-M887 HydrophobicContact CD1-CE 4.06Å; L747-M887 HydrophobicContact CD1-CE 4.12Å; L881-M887 WeakPolarHBondContact O-CB 3.15Å; L881-M887 WeakPolarHBondContact O-CE 3.46Å; L881-M887 WeakPolarHBondContact O-CG 3.24Å; L882-M887 WeakPolarHBondContact O-CG 3.43Å; C884-M887 PolarHBondContact O-N 3.15Å; C884-M887 PolarHBondContact SG-N 3.08Å; M887-Y889 PolarHBondContact O-N 3.15Å; M887-I890 PolarHBondContact O-N 2.98Å; M887-L891 HydrophobicContact CG-CD1 3.9Å; M887-L891 HydrophobicContact CG-CG 4.48Å; M887-L891 WeakPolarHBondContact O-CG 3.34Å; M887-L891 PolarHBondContact O-N 3.3Å; M887-L891 HydrophobicContact SD-CD1 4.09Å; M887-L891 HydrophobicContact SD-CG 4.2Å; M887-I917 HydrophobicContact CE-CG2 4.33Å; M887-I917 HydrophobicContact SD-CG2 3.83Å
888M94.7Very high94.2Very high9 Ų917 Ų174%0.0448%0.082CC..Hα-helixtrans-60.2-36.5176.8-68.7-72.5160.900111.8C884 D885 R892 F941 K944 A945 I955C884-M888 WeakPolarHBondContact O-CG 3.39Å; C884-M888 PolarHBondContact O-N 3.33Å; D885-M888 PolarHBondContact O-N 3.05Å; M888-R892 WeakPolarHBondContact O-CB 3.27Å; M888-R892 VanDerWaalsContact O-CD 3.27Å; M888-R892 WeakPolarHBondContact O-CD 3.39Å; M888-R892 WeakPolarHBondContact O-CG 3.35Å; M888-R892 PolarHBondContact O-N 2.87Å; M888-R892 VanDerWaalsContact O-N 3.08Å; M888-F941 HydrophobicContact CE-CD2 3.46Å; M888-F941 VanDerWaalsContact CE-CD2 3.46Å; M888-F941 HydrophobicContact CE-CE2 3.4Å; M888-F941 HydrophobicContact CE-CG 4.17Å; M888-F941 HydrophobicContact CE-CZ 4.05Å; M888-K944 HydrophobicContact CE-CB 3.8Å; M888-K944 HydrophobicContact CG-CB 4.26Å; M888-K944 HydrophobicContact SD-CB 4.08Å; M888-A945 HydrophobicContact CE-CB 4.41Å; M888-A945 HydrophobicContact SD-CB 4.23Å; M888-I955 HydrophobicContact SD-CD1 4.03Å
889Y93.5Very high93.7Very high50 Ų5019.2 Ų19.220%0.1969%0.093CC..Hα-helixtrans-68.8-44.8174.7171.9-117.8000112.9S588 C589 F721 D885 I886 M887 L891 T893S588-Y889 WeakPolarHBondContact OG-CE1 3.48Å; C589-Y889 WeakPolarHBondContact SG-CB 3.47Å; F721-Y889 VanDerWaalsContact C-OH 3.24Å; F721-Y889 HydrophobicContact CB-CE1 4.03Å; F721-Y889 PolarHBondContact O-OH 3.22Å; D885-Y889 WeakPolarHBondContact O-CB 3.39Å; D885-Y889 PolarHBondContact O-N 3.31Å; I886-Y889 PolarHBondContact O-N 3.4Å; M887-Y889 PolarHBondContact O-N 3.15Å; Y889-L891 PolarHBondContact O-N 2.83Å; Y889-T893 WeakPolarHBondContact CE2-OG1 3.33Å; Y889-T893 VanDerWaalsContact O-CB 3.28Å; Y889-T893 WeakPolarHBondContact O-CB 3.47Å; Y889-T893 PolarHBondContact O-N 3.46Å; Y889-T893 PolarHBondContact O-OG1 2.69Å
890I94.9Very high93.1Very high1 Ų122.1 Ų22.11%0.00511%0.109CC..Hα-helixtrans-57.5-51.9175.3-70.9163.8000109.9L708 L712 F721 M743 L744 I886 M887 T893 V894L708-I890 HydrophobicContact CD1-CD1 4.47Å; L712-I890 HydrophobicContact CD1-CD1 4.11Å; L712-I890 HydrophobicContact CD1-CG1 4.42Å; L712-I890 HydrophobicContact CD2-CD1 4.28Å; L712-I890 HydrophobicContact CD2-CG1 4.48Å; L712-I890 HydrophobicContact CG-CD1 4.31Å; F721-I890 HydrophobicContact CD1-CG1 4.44Å; F721-I890 HydrophobicContact CE1-CB 4.22Å; F721-I890 HydrophobicContact CE1-CG1 4.22Å; F721-I890 HydrophobicContact CE1-CG2 3.97Å; F721-I890 HydrophobicContact CZ-CG2 4.07Å; M743-I890 HydrophobicContact CE-CD1 4.49Å; M743-I890 HydrophobicContact CE-CG2 4.4Å; L744-I890 HydrophobicContact CD2-CG2 3.93Å; I886-I890 HydrophobicContact CG2-CD1 4Å; I886-I890 HydrophobicContact CG2-CG1 4.48Å; I886-I890 VanDerWaalsContact O-CG1 3.3Å; I886-I890 WeakPolarHBondContact O-CG1 3.27Å; I886-I890 PolarHBondContact O-N 2.89Å; M887-I890 PolarHBondContact O-N 2.98Å; I890-T893 PolarHBondContact O-N 3.45Å; I890-V894 WeakPolarHBondContact O-CG2 3.48Å; I890-V894 PolarHBondContact O-N 3.43Å
891L95.4Very high91.8Very high0 Ų024.3 Ų24.30%013%0.125CC..Hα-helixtrans-60.9-49-177.5-68.9168.3000112M887 Y889 T893 V894 F895 A914 I917 L918 I955M887-L891 HydrophobicContact CG-CD1 3.9Å; M887-L891 HydrophobicContact CG-CG 4.48Å; M887-L891 WeakPolarHBondContact O-CG 3.34Å; M887-L891 PolarHBondContact O-N 3.3Å; M887-L891 HydrophobicContact SD-CD1 4.09Å; M887-L891 HydrophobicContact SD-CG 4.2Å; Y889-L891 PolarHBondContact O-N 2.83Å; L891-T893 VanDerWaalsContact C-N 3.34Å; L891-T893 PolarHBondContact O-N 2.75Å; L891-V894 PolarHBondContact O-N 2.91Å; L891-F895 HydrophobicContact CB-CE2 4.06Å; L891-F895 WeakPolarHBondContact O-CD2 3.29Å; L891-F895 WeakPolarHBondContact O-CG 3.22Å; L891-F895 PolarHBondContact O-N 2.78Å; L891-F895 VanDerWaalsContact O-N 3.08Å; L891-A914 HydrophobicContact CD2-CB 3.83Å; L891-I917 HydrophobicContact CD1-CG2 4.1Å; L891-I917 HydrophobicContact CD2-CB 4.19Å; L891-I917 HydrophobicContact CD2-CG2 4.09Å; L891-L918 HydrophobicContact CD1-CD2 3.93Å; L891-I955 HydrophobicContact CB-CD1 4.32Å
892R92.8Very high90.6Very high24 Ų2431 Ų319%0.09116%0.161CC..Hα-helixtrans-57.4-47.4175.2-72.1164.4-166.9-96.11.6111.5M888 V894 F895 E896 K944 A945 R947 G949 M953 I955 L958M888-R892 WeakPolarHBondContact O-CB 3.27Å; M888-R892 VanDerWaalsContact O-CD 3.27Å; M888-R892 WeakPolarHBondContact O-CD 3.39Å; M888-R892 WeakPolarHBondContact O-CG 3.35Å; M888-R892 PolarHBondContact O-N 2.87Å; M888-R892 VanDerWaalsContact O-N 3.08Å; R892-V894 VanDerWaalsContact C-N 3.33Å; R892-V894 PolarHBondContact O-N 2.94Å; R892-F895 PolarHBondContact O-N 2.76Å; R892-E896 WeakPolarHBondContact O-CB 3.3Å; R892-E896 VanDerWaalsContact O-CG 3.29Å; R892-E896 WeakPolarHBondContact O-CG 3.33Å; R892-E896 PolarHBondContact O-N 2.68Å; R892-K944 PolarHBondContact NH2-O 3.27Å; R892-A945 PolarHBondContact NH2-O 3.43Å; R892-R947 VanDerWaalsContact CZ-O 3.26Å; R892-R947 PolarHBondContact NH1-O 3.32Å; R892-R947 PolarHBondContact NH2-O 3.06Å; R892-G949 VanDerWaalsContact NH1-N 3.14Å; R892-M953 PolarHBondContact NH1-O 3.35Å; R892-I955 HydrophobicContact CG-CD1 4.17Å; R892-I955 HydrophobicContact CG-CG1 3.79Å; R892-L958 HydrophobicContact CG-CD1 4.46Å
893T91.6Very high89.8Confident13 Ų1331.7 Ų31.78%0.0817%0.166CC..Hα-helixtrans-59.9-41.6-179.2-57.50000112.2F721 Y889 I890 L891 R897F721-T893 HydrophobicContact CD1-CG2 3.61Å; F721-T893 HydrophobicContact CE1-CG2 3.95Å; Y889-T893 WeakPolarHBondContact CE2-OG1 3.33Å; Y889-T893 VanDerWaalsContact O-CB 3.28Å; Y889-T893 WeakPolarHBondContact O-CB 3.47Å; Y889-T893 PolarHBondContact O-N 3.46Å; Y889-T893 PolarHBondContact O-OG1 2.69Å; I890-T893 PolarHBondContact O-N 3.45Å; L891-T893 VanDerWaalsContact C-N 3.34Å; L891-T893 PolarHBondContact O-N 2.75Å; T893-R897 VanDerWaalsContact O-CG 3.25Å; T893-R897 WeakPolarHBondContact O-CG 3.38Å; T893-R897 PolarHBondContact O-N 3.4Å; T893-R897 VanDerWaalsContact O-N 3.11Å
894V93Very high89.2Confident2 Ų235.5 Ų35.51%0.01219%0.187CC..Hα-helixtrans-65.1-44.9176.6170.50000111.3F721 I890 L891 R892 A898 M910 L911 A914F721-V894 HydrophobicContact CE1-CG2 4.27Å; F721-V894 HydrophobicContact CZ-CG2 4.36Å; I890-V894 WeakPolarHBondContact O-CG2 3.48Å; I890-V894 PolarHBondContact O-N 3.43Å; L891-V894 PolarHBondContact O-N 2.91Å; R892-V894 VanDerWaalsContact C-N 3.33Å; R892-V894 PolarHBondContact O-N 2.94Å; V894-A898 PolarHBondContact O-N 3.07Å; V894-M910 HydrophobicContact CG1-CB 4.16Å; V894-L911 HydrophobicContact CG1-CD2 4.06Å; V894-A914 HydrophobicContact CG1-CB 4.19Å
895F93.1Very high88.7Confident0 Ų036.6 Ų36.60%019%0.192CC..Hα-helixtrans-69-37.5178.5-61.2-42.4000113.3L891 R892 A898 I899 L911 A914 F915 L918 I955 L958 L962L891-F895 HydrophobicContact CB-CE2 4.06Å; L891-F895 WeakPolarHBondContact O-CD2 3.29Å; L891-F895 WeakPolarHBondContact O-CG 3.22Å; L891-F895 PolarHBondContact O-N 2.78Å; L891-F895 VanDerWaalsContact O-N 3.08Å; R892-F895 PolarHBondContact O-N 2.76Å; F895-A898 PolarHBondContact O-N 3.04Å; F895-I899 WeakPolarHBondContact O-CG1 3.32Å; F895-I899 PolarHBondContact O-N 3.48Å; F895-L911 HydrophobicContact CD1-CD2 3.68Å; F895-L911 HydrophobicContact CE1-CD2 4.08Å; F895-A914 HydrophobicContact CE1-CB 3.62Å; F895-A914 HydrophobicContact CZ-CB 3.6Å; F895-F915 HydrophobicContact CD1-CE1 4.05Å; F895-F915 AromaticContact CE1-CD1 3.58Å; F895-F915 HydrophobicContact CE1-CD1 3.58Å; F895-F915 AromaticContact CE1-CE1 3.43Å; F895-F915 HydrophobicContact CE1-CE1 3.43Å; F895-F915 VanDerWaalsContact CE1-CE1 3.43Å; F895-F915 HydrophobicContact CE1-CZ 4.49Å; F895-F915 AromaticContact CZ-CD1 3.97Å; F895-F915 HydrophobicContact CZ-CD1 3.97Å; F895-F915 HydrophobicContact CZ-CE1 4.18Å; F895-L918 HydrophobicContact CE2-CD1 3.58Å; F895-L918 HydrophobicContact CE2-CD2 4.46Å; F895-L918 HydrophobicContact CE2-CG 4.12Å; F895-L918 HydrophobicContact CZ-CD1 3.51Å; F895-L918 HydrophobicContact CZ-CG 4.06Å; F895-I955 HydrophobicContact CD2-CG2 4.26Å; F895-I955 HydrophobicContact CE2-CG2 4.03Å; F895-L958 HydrophobicContact CB-CB 4.15Å; F895-L958 HydrophobicContact CB-CD1 4.15Å; F895-L962 HydrophobicContact CB-CD1 3.95Å; F895-L962 HydrophobicContact CD1-CD1 3.57Å; F895-L962 HydrophobicContact CE1-CD1 4.42Å; F895-L962 HydrophobicContact CG-CD1 3.99Å
896E90.4Very high88.5Confident56 Ų5636 Ų3626%0.26219%0.185SC..Hα-helixtrans-64.3-42.1176.4-75.3170.9-177.700111.5R892 A898 I899 D900 S951 L958R892-E896 WeakPolarHBondContact O-CB 3.3Å; R892-E896 VanDerWaalsContact O-CG 3.29Å; R892-E896 WeakPolarHBondContact O-CG 3.33Å; R892-E896 PolarHBondContact O-N 2.68Å; E896-A898 VanDerWaalsContact C-N 3.27Å; E896-A898 PolarHBondContact O-N 3.14Å; E896-I899 PolarHBondContact O-N 2.87Å; E896-D900 PolarHBondContact O-N 3.43Å; E896-S951 WeakPolarHBondContact OE1-CB 3.29Å; E896-S951 PolarHBondContact OE1-OG 2.94Å; E896-L958 HydrophobicContact CG-CD1 4.07Å; E896-L958 HydrophobicContact CG-CD2 3.85Å
897R89.2Confident88.4Confident31 Ų3137.8 Ų37.812%0.11720%0.196CC..Hα-helixtrans-61.3-32.1175.1-75170.5-169.4-167.81.5113.9A720 T893 S903 L905 W906A720-R897 PolarHBondContact O-NH2 3.39Å; T893-R897 VanDerWaalsContact O-CG 3.25Å; T893-R897 WeakPolarHBondContact O-CG 3.38Å; T893-R897 PolarHBondContact O-N 3.4Å; T893-R897 VanDerWaalsContact O-N 3.11Å; R897-S903 WeakPolarHBondContact O-CB 3.44Å; R897-S903 PolarHBondContact O-OG 3.24Å; R897-L905 WeakPolarHBondContact CD-O 3.33Å; R897-W906 HydrophobicContact CB-CB 4.31Å
898A89.8Confident88.2Confident2 Ų241.6 Ų41.62%0.01721%0.214CC..Hα-helixtrans-81.9-15.8178.800000113.9V894 F895 E896 W906 L911 L962 I965V894-A898 PolarHBondContact O-N 3.07Å; F895-A898 PolarHBondContact O-N 3.04Å; E896-A898 VanDerWaalsContact C-N 3.27Å; E896-A898 PolarHBondContact O-N 3.14Å; A898-W906 HydrophobicContact CB-CB 4.45Å; A898-W906 HydrophobicContact CB-CD2 3.78Å; A898-W906 HydrophobicContact CB-CE3 4Å; A898-W906 HydrophobicContact CB-CG 3.98Å; A898-L911 HydrophobicContact CB-CD1 3.75Å; A898-L911 HydrophobicContact CB-CD2 3.78Å; A898-L911 HydrophobicContact CB-CG 4.24Å; A898-L962 HydrophobicContact CB-CD2 3.74Å; A898-I965 WeakPolarHBondContact O-CD1 3.43Å
899I87.8Confident88.1Confident46 Ų4642 Ų4224%0.23622%0.22CC..Hα-helixtrans-82.7-29.1172-68.3166.4000111F895 E896 T901 L958 K961 L962F895-I899 WeakPolarHBondContact O-CG1 3.32Å; F895-I899 PolarHBondContact O-N 3.48Å; E896-I899 PolarHBondContact O-N 2.87Å; I899-T901 PolarHBondContact O-N 3.44Å; I899-L958 HydrophobicContact CD1-CB 4.14Å; I899-L958 HydrophobicContact CD1-CD2 3.44Å; I899-L958 VanDerWaalsContact CD1-CD2 3.44Å; I899-L958 HydrophobicContact CD1-CG 4.4Å; I899-K961 HydrophobicContact CD1-CB 3.91Å; I899-K961 HydrophobicContact CD1-CD 4.11Å; I899-K961 HydrophobicContact CG1-CB 4.24Å; I899-K961 HydrophobicContact CG2-CD 4.24Å; I899-L962 HydrophobicContact CD1-CG 4.42Å; I899-L962 HydrophobicContact CG1-CD2 3.73Å; I899-L962 HydrophobicContact CG1-CG 4.11Å
900D83.6Confident88.1Confident83 Ų8339.7 Ų39.744%0.44421%0.211SC..  trans-73.2103.8171.4-175.4-0.3000110.5E896 D902 S903E896-D900 PolarHBondContact O-N 3.43Å; D900-D902 PolarHBondContact O-N 2.99Å; D900-D902 PolarHBondContact OD1-N 3.21Å; D900-D902 VanDerWaalsContact OD1-N 3.13Å; D900-S903 WeakPolarHBondContact O-CB 3.44Å; D900-S903 PolarHBondContact O-N 3.3Å; D900-S903 VanDerWaalsContact O-N 3.15Å
901T69.3Low88.1Confident111 Ų11139.6 Ų39.668%0.68121%0.211SC*.THydrogen-bonded Turntrans-67.9-15.8-177.150.70000114.2I899I899-T901 PolarHBondContact O-N 3.44Å
902D72.1Confident88.1Confident142 Ų14240.6 Ų40.676%0.75922%0.216SC*.THydrogen-bonded Turntrans-93.9-3.7177.8-63.8-26.4000112.2D900D900-D902 PolarHBondContact O-N 2.99Å; D900-D902 PolarHBondContact OD1-N 3.21Å; D900-D902 VanDerWaalsContact OD1-N 3.13Å
903S78Confident88.3Confident17 Ų1740 Ų4012%0.11921%0.214CC..  trans-84.6124.3-1791770000112.7R897 D900 L905 W906R897-S903 WeakPolarHBondContact O-CB 3.44Å; R897-S903 PolarHBondContact O-OG 3.24Å; D900-S903 WeakPolarHBondContact O-CB 3.44Å; D900-S903 PolarHBondContact O-N 3.3Å; D900-S903 VanDerWaalsContact O-N 3.15Å; S903-L905 VanDerWaalsContact C-N 3.35Å; S903-L905 PolarHBondContact OG-N 3.45Å; S903-W906 VanDerWaalsContact O-CD1 3.29Å; S903-W906 PolarHBondContact O-NE1 3.02Å
904N82.6Confident88.6Confident94 Ų9439.4 Ų39.450%0.50321%0.21SC..  trans-91.46.7169.8-61.9-58.4000113.1I733 N737 W906I733-N904 HydrophobicContact CG2-CB 4.13Å; I733-N904 VanDerWaalsContact CG2-O 3.29Å; I733-N904 WeakPolarHBondContact CG2-O 3.24Å; N737-N904 PolarHBondContact ND2-O 3.08Å; N904-W906 VanDerWaalsContact C-N 3.29Å; N904-W906 PolarHBondContact O-N 3.35Å
905L85Confident88.8Confident26 Ų2639.3 Ų39.314%0.13621%0.21CC..SBendtrans-92.128.9-172.2-61.9173.6000113.4I725 I733 R897 S903I725-L905 HydrophobicContact CB-CD1 4.25Å; I725-L905 HydrophobicContact CD1-CD2 4.25Å; I733-L905 HydrophobicContact CG1-CD2 4.17Å; I733-L905 HydrophobicContact CG2-CD2 4.29Å; R897-L905 WeakPolarHBondContact CD-O 3.33Å; S903-L905 VanDerWaalsContact C-N 3.35Å; S903-L905 PolarHBondContact OG-N 3.45Å
906W90.5Very high89Confident49 Ų4939.5 Ų39.519%0.18621%0.211CC..  trans-149.3160.9177.772.3-84.6000111.5R897 A898 S903 N904 M910 L911 Q967 L968R897-W906 HydrophobicContact CB-CB 4.31Å; A898-W906 HydrophobicContact CB-CB 4.45Å; A898-W906 HydrophobicContact CB-CD2 3.78Å; A898-W906 HydrophobicContact CB-CE3 4Å; A898-W906 HydrophobicContact CB-CG 3.98Å; S903-W906 VanDerWaalsContact O-CD1 3.29Å; S903-W906 PolarHBondContact O-NE1 3.02Å; N904-W906 VanDerWaalsContact C-N 3.29Å; N904-W906 PolarHBondContact O-N 3.35Å; W906-M910 HydrophobicContact CB-SD 4.45Å; W906-L911 HydrophobicContact CE3-CD1 3.5Å; W906-L911 HydrophobicContact CE3-CG 4.25Å; W906-L911 HydrophobicContact CZ3-CD1 3.52Å; W906-Q967 HydrophobicContact CH2-CB 4.32Å; W906-L968 HydrophobicContact CH2-CD2 4.25Å; W906-L968 HydrophobicContact CZ3-CD2 3.99Å
907T92.4Very high89.3Confident37 Ų3736.9 Ų36.923%0.22720%0.199CC..  trans-139162.717264.50000110.2N737 E741 G909 M910 L911N737-T907 HydrophobicContact CB-CG2 4.03Å; E741-T907 WeakPolarHBondContact OE1-CB 3.43Å; E741-T907 WeakPolarHBondContact OE1-CG2 3.43Å; E741-T907 PolarHBondContact OE1-OG1 2.98Å; T907-G909 PolarHBondContact O-N 2.99Å; T907-M910 HydrophobicContact CG2-CE 4.13Å; T907-M910 PolarHBondContact O-N 2.64Å; T907-M910 WeakPolarHBondContact OG1-CG 3.18Å; T907-M910 PolarHBondContact OG1-N 2.63Å; T907-L911 PolarHBondContact O-N 2.93Å
908E91.6Very high89.7Confident80 Ų8035.4 Ų35.437%0.37419%0.193SC..Hα-helixtrans-60.5-37.2173.4-165.5-173.2158.800111.6M910 L911 Q912 L968 Q971E908-M910 PolarHBondContact O-N 3.3Å; E908-L911 PolarHBondContact O-N 2.63Å; E908-L911 VanDerWaalsContact O-N 3.11Å; E908-Q912 HydrophobicContact CG-CG 4.43Å; E908-Q912 WeakPolarHBondContact O-CG 3.4Å; E908-Q912 PolarHBondContact O-N 2.92Å; E908-Q912 PolarHBondContact OE1-NE2 3.39Å; E908-L968 HydrophobicContact CG-CD2 4.42Å; E908-Q971 HydrophobicContact CG-CG 4.27Å; E908-Q971 WeakPolarHBondContact OE1-CG 3.35Å; E908-Q971 PolarHBondContact OE1-NE2 2.89Å
909G92.7Very high90Very high18 Ų1835.3 Ų35.319%0.18619%0.192CC..Hα-helixtrans-58-46.1177.600000113T907 L911 Q912 M913T907-G909 PolarHBondContact O-N 2.99Å; G909-L911 VanDerWaalsContact C-N 3.29Å; G909-L911 PolarHBondContact O-N 3.46Å; G909-Q912 PolarHBondContact O-N 3.31Å; G909-M913 WeakPolarHBondContact O-CG 3.43Å; G909-M913 PolarHBondContact O-N 3.02Å
910M95Very high90.4Very high1 Ų133.5 Ų33.51%0.00518%0.183CC..Hα-helixtrans-57.8-42.4174-68179.1-153.600112.4N737 I740 E741 L744 V894 W906 T907 E908 M913 A914N737-M910 HydrophobicContact CB-CE 3.44Å; N737-M910 VanDerWaalsContact CB-CE 3.44Å; N737-M910 WeakPolarHBondContact O-CE 3.35Å; N737-M910 WeakPolarHBondContact OD1-CE 3.14Å; I740-M910 HydrophobicContact CB-CE 4.07Å; I740-M910 HydrophobicContact CB-SD 4.2Å; I740-M910 HydrophobicContact CD1-CE 4.34Å; I740-M910 HydrophobicContact CG2-CE 4.25Å; I740-M910 HydrophobicContact CG2-CG 3.95Å; I740-M910 HydrophobicContact CG2-SD 3.7Å; E741-M910 HydrophobicContact CG-CB 4.49Å; E741-M910 HydrophobicContact CG-CG 3.6Å; L744-M910 HydrophobicContact CD1-CB 4.2Å; L744-M910 HydrophobicContact CD1-CG 4.45Å; V894-M910 HydrophobicContact CG1-CB 4.16Å; W906-M910 HydrophobicContact CB-SD 4.45Å; T907-M910 HydrophobicContact CG2-CE 4.13Å; T907-M910 PolarHBondContact O-N 2.64Å; T907-M910 WeakPolarHBondContact OG1-CG 3.18Å; T907-M910 PolarHBondContact OG1-N 2.63Å; E908-M910 PolarHBondContact O-N 3.3Å; M910-M913 PolarHBondContact O-N 3.36Å; M910-A914 VanDerWaalsContact O-CB 3.3Å; M910-A914 WeakPolarHBondContact O-CB 3.36Å; M910-A914 PolarHBondContact O-N 2.94Å
911L95.1Very high91Very high0 Ų029.5 Ų29.50%016%0.162CC..Hα-helixtrans-68.7-43.1-178-69.5170.9000111V894 F895 A898 W906 T907 E908 G909 M913 A914 F915 L962 L968V894-L911 HydrophobicContact CG1-CD2 4.06Å; F895-L911 HydrophobicContact CD1-CD2 3.68Å; F895-L911 HydrophobicContact CE1-CD2 4.08Å; A898-L911 HydrophobicContact CB-CD1 3.75Å; A898-L911 HydrophobicContact CB-CD2 3.78Å; A898-L911 HydrophobicContact CB-CG 4.24Å; W906-L911 HydrophobicContact CE3-CD1 3.5Å; W906-L911 HydrophobicContact CE3-CG 4.25Å; W906-L911 HydrophobicContact CZ3-CD1 3.52Å; T907-L911 PolarHBondContact O-N 2.93Å; E908-L911 PolarHBondContact O-N 2.63Å; E908-L911 VanDerWaalsContact O-N 3.11Å; G909-L911 VanDerWaalsContact C-N 3.29Å; G909-L911 PolarHBondContact O-N 3.46Å; L911-M913 VanDerWaalsContact C-N 3.3Å; L911-M913 PolarHBondContact O-N 2.87Å; L911-A914 PolarHBondContact O-N 3.04Å; L911-F915 HydrophobicContact CB-CE2 4.06Å; L911-F915 HydrophobicContact CB-CZ 4.15Å; L911-F915 VanDerWaalsContact O-CB 3.25Å; L911-F915 WeakPolarHBondContact O-CB 3.39Å; L911-F915 WeakPolarHBondContact O-CD2 3.32Å; L911-F915 WeakPolarHBondContact O-CG 3.4Å; L911-F915 PolarHBondContact O-N 2.98Å; L911-L962 HydrophobicContact CD2-CD1 4.5Å; L911-L968 HydrophobicContact CD1-CD1 3.82Å; L911-L968 HydrophobicContact CD1-CD2 3.59Å; L911-L968 HydrophobicContact CD1-CG 4.36Å
912Q94.7Very high92.3Very high21 Ų2124.2 Ų24.210%0.09813%0.129CC..Hα-helixtrans-57.5-42.8173.4-66.6177.37.400111.6Y834 E908 G909 F915 H916Y834-Q912 VanDerWaalsContact OH-C 3.29Å; Y834-Q912 WeakPolarHBondContact OH-CB 3.5Å; E908-Q912 HydrophobicContact CG-CG 4.43Å; E908-Q912 WeakPolarHBondContact O-CG 3.4Å; E908-Q912 PolarHBondContact O-N 2.92Å; E908-Q912 PolarHBondContact OE1-NE2 3.39Å; G909-Q912 PolarHBondContact O-N 3.31Å; Q912-F915 PolarHBondContact O-N 3.5Å; Q912-H916 WeakPolarHBondContact O-CB 3.41Å; Q912-H916 PolarHBondContact O-N 2.98Å
913M96.8Very high93.4Very high12 Ų1218.1 Ų18.16%0.05910%0.096CC..Hα-helixtrans-67.4-44.7176.7-68.3173.7-178.600112E741 L744 Q745 I748 Y834 G909 M910 L911 F915 H916 I917E741-M913 HydrophobicContact CB-CE 4.29Å; E741-M913 HydrophobicContact CB-SD 4.15Å; L744-M913 HydrophobicContact CB-CB 3.94Å; L744-M913 HydrophobicContact CB-SD 4.04Å; L744-M913 HydrophobicContact CD1-CB 4.36Å; Q745-M913 HydrophobicContact CB-CE 3.89Å; Q745-M913 HydrophobicContact CB-SD 4.04Å; Q745-M913 HydrophobicContact CG-CE 4.27Å; I748-M913 HydrophobicContact CD1-CB 3.82Å; I748-M913 HydrophobicContact CD1-CG 4.02Å; Y834-M913 HydrophobicContact CE1-CE 3.94Å; Y834-M913 HydrophobicContact CE1-CG 3.72Å; Y834-M913 HydrophobicContact CE2-CG 4.22Å; Y834-M913 WeakPolarHBondContact OH-CG 3.42Å; Y834-M913 PolarHBondContact OH-N 3.45Å; G909-M913 WeakPolarHBondContact O-CG 3.43Å; G909-M913 PolarHBondContact O-N 3.02Å; M910-M913 PolarHBondContact O-N 3.36Å; L911-M913 VanDerWaalsContact C-N 3.3Å; L911-M913 PolarHBondContact O-N 2.87Å; M913-F915 VanDerWaalsContact C-N 3.35Å; M913-F915 PolarHBondContact O-N 3.18Å; M913-H916 WeakPolarHBondContact O-CB 3.49Å; M913-H916 PolarHBondContact O-N 3.43Å; M913-H916 VanDerWaalsContact O-N 3.11Å; M913-I917 WeakPolarHBondContact O-CG1 3.45Å; M913-I917 PolarHBondContact O-N 2.97Å
914A97.4Very high94.2Very high0 Ų018 Ų180%09%0.094CC..Hα-helixtrans-63.3-39.1176.300000112.2L891 V894 F895 M910 L911 H916 I917 L918L891-A914 HydrophobicContact CD2-CB 3.83Å; V894-A914 HydrophobicContact CG1-CB 4.19Å; F895-A914 HydrophobicContact CE1-CB 3.62Å; F895-A914 HydrophobicContact CZ-CB 3.6Å; M910-A914 VanDerWaalsContact O-CB 3.3Å; M910-A914 WeakPolarHBondContact O-CB 3.36Å; M910-A914 PolarHBondContact O-N 2.94Å; L911-A914 PolarHBondContact O-N 3.04Å; A914-H916 VanDerWaalsContact C-N 3.32Å; A914-H916 PolarHBondContact O-N 3.36Å; A914-I917 PolarHBondContact O-N 3.24Å; A914-L918 WeakPolarHBondContact O-CG 3.47Å; A914-L918 PolarHBondContact O-N 3.4Å
915F97.1Very high94.8Very high0 Ų013.5 Ų13.50%07%0.07CC..Hα-helixtrans-61.2-39171-68.1-20.4000111.8F895 L911 Q912 M913 L918 A919 L959 L962 Q971 M974 I975 I978F895-F915 HydrophobicContact CD1-CE1 4.05Å; F895-F915 AromaticContact CE1-CD1 3.58Å; F895-F915 HydrophobicContact CE1-CD1 3.58Å; F895-F915 AromaticContact CE1-CE1 3.43Å; F895-F915 HydrophobicContact CE1-CE1 3.43Å; F895-F915 VanDerWaalsContact CE1-CE1 3.43Å; F895-F915 HydrophobicContact CE1-CZ 4.49Å; F895-F915 AromaticContact CZ-CD1 3.97Å; F895-F915 HydrophobicContact CZ-CD1 3.97Å; F895-F915 HydrophobicContact CZ-CE1 4.18Å; L911-F915 HydrophobicContact CB-CE2 4.06Å; L911-F915 HydrophobicContact CB-CZ 4.15Å; L911-F915 VanDerWaalsContact O-CB 3.25Å; L911-F915 WeakPolarHBondContact O-CB 3.39Å; L911-F915 WeakPolarHBondContact O-CD2 3.32Å; L911-F915 WeakPolarHBondContact O-CG 3.4Å; L911-F915 PolarHBondContact O-N 2.98Å; Q912-F915 PolarHBondContact O-N 3.5Å; M913-F915 VanDerWaalsContact C-N 3.35Å; M913-F915 PolarHBondContact O-N 3.18Å; F915-L918 PolarHBondContact O-N 2.95Å; F915-A919 WeakPolarHBondContact O-CB 3.31Å; F915-A919 PolarHBondContact O-N 3.47Å; F915-L959 HydrophobicContact CD1-CD2 3.86Å; F915-L959 HydrophobicContact CE1-CD2 3.51Å; F915-L962 HydrophobicContact CE1-CD1 4.11Å; F915-L962 HydrophobicContact CZ-CD1 4.27Å; F915-Q971 HydrophobicContact CE2-CB 4.11Å; F915-M974 HydrophobicContact CB-CE 4.46Å; F915-M974 HydrophobicContact CB-CG 4.38Å; F915-I975 HydrophobicContact CD2-CG1 4.43Å; F915-I975 HydrophobicContact CE1-CG1 4.15Å; F915-I975 HydrophobicContact CE2-CD1 4.09Å; F915-I975 HydrophobicContact CE2-CG1 3.76Å; F915-I975 HydrophobicContact CZ-CD1 3.8Å; F915-I975 HydrophobicContact CZ-CG1 3.61Å; F915-I978 HydrophobicContact CB-CD1 3.58Å; F915-I978 HydrophobicContact CD1-CD1 4.12Å; F915-I978 HydrophobicContact CG-CD1 3.99Å; F915-I978 WeakPolarHBondContact O-CD1 3.17Å
916H97.1Very high95.3Very high3 Ų314.7 Ų14.71%0.0147%0.074CC..Hα-helixtrans-69.6-40.7176.9-16799.9000112.4I748 N832 Y834 P865 Q912 M913 A914 A919 L920I748-H916 HydrophobicContact CD1-CB 4.17Å; N832-H916 PolarHBondContact OD1-CE1 2.95Å; N832-H916 VanDerWaalsContact OD1-CE1 3.27Å; Y834-H916 HydrophobicContact CD2-CB 3.91Å; Y834-H916 AromaticContact CD2-CD2 3.84Å; Y834-H916 AromaticContact CD2-CE1 3.8Å; Y834-H916 AromaticContact CD2-CG 3.52Å; Y834-H916 AromaticContact CD2-ND1 3.51Å; Y834-H916 HydrophobicContact CE2-CB 3.65Å; Y834-H916 AromaticContact CE2-CG 3.78Å; Y834-H916 AromaticContact CE2-ND1 3.9Å; P865-H916 VanDerWaalsContact CB-CE1 3.43Å; P865-H916 WeakPolarHBondContact CB-CE1 2.82Å; Q912-H916 WeakPolarHBondContact O-CB 3.41Å; Q912-H916 PolarHBondContact O-N 2.98Å; M913-H916 WeakPolarHBondContact O-CB 3.49Å; M913-H916 PolarHBondContact O-N 3.43Å; M913-H916 VanDerWaalsContact O-N 3.11Å; A914-H916 VanDerWaalsContact C-N 3.32Å; A914-H916 PolarHBondContact O-N 3.36Å; H916-A919 PolarHBondContact O-N 3.42Å; H916-L920 WeakPolarHBondContact O-CG 3.22Å; H916-L920 PolarHBondContact O-N 3.43Å
917I97.7Very high95.4Very high2 Ų213.6 Ų13.61%0.017%0.071CC..Hα-helixtrans-61.4-44.1172.7-65.9170.7000110.9L744 L747 I748 L882 M887 L891 M913 A914 A919 L920 G921L744-I917 HydrophobicContact CB-CD1 4.45Å; L744-I917 HydrophobicContact CD2-CD1 3.87Å; L747-I917 HydrophobicContact CB-CD1 4.43Å; I748-I917 HydrophobicContact CD1-CG1 4.22Å; I748-I917 HydrophobicContact CG1-CD1 4.09Å; I748-I917 HydrophobicContact CG1-CG1 3.54Å; L882-I917 HydrophobicContact CD2-CG2 3.84Å; M887-I917 HydrophobicContact CE-CG2 4.33Å; M887-I917 HydrophobicContact SD-CG2 3.83Å; L891-I917 HydrophobicContact CD1-CG2 4.1Å; L891-I917 HydrophobicContact CD2-CB 4.19Å; L891-I917 HydrophobicContact CD2-CG2 4.09Å; M913-I917 WeakPolarHBondContact O-CG1 3.45Å; M913-I917 PolarHBondContact O-N 2.97Å; A914-I917 PolarHBondContact O-N 3.24Å; I917-A919 VanDerWaalsContact C-N 3.34Å; I917-A919 PolarHBondContact O-N 3.29Å; I917-L920 PolarHBondContact O-N 3.04Å; I917-G921 PolarHBondContact O-N 3.35Å
918L96.9Very high95.4Very high0 Ų013.9 Ų13.90%07%0.07CC..Hα-helixtrans-58.9-45.1173-74.3-176000112.2L891 F895 A914 F915 G921 L922 F941 I955 L959 I978L891-L918 HydrophobicContact CD1-CD2 3.93Å; F895-L918 HydrophobicContact CE2-CD1 3.58Å; F895-L918 HydrophobicContact CE2-CD2 4.46Å; F895-L918 HydrophobicContact CE2-CG 4.12Å; F895-L918 HydrophobicContact CZ-CD1 3.51Å; F895-L918 HydrophobicContact CZ-CG 4.06Å; A914-L918 WeakPolarHBondContact O-CG 3.47Å; A914-L918 PolarHBondContact O-N 3.4Å; F915-L918 PolarHBondContact O-N 2.95Å; L918-G921 PolarHBondContact O-N 2.97Å; L918-L922 WeakPolarHBondContact O-CG 3.39Å; L918-L922 PolarHBondContact O-N 2.85Å; L918-F941 HydrophobicContact CD2-CE1 4.41Å; L918-F941 HydrophobicContact CD2-CZ 3.95Å; L918-I955 HydrophobicContact CD1-CG2 3.71Å; L918-I955 HydrophobicContact CD2-CD1 4.14Å; L918-I955 HydrophobicContact CD2-CG2 3.87Å; L918-I955 HydrophobicContact CG-CG2 4.46Å; L918-L959 HydrophobicContact CD1-CD1 4.02Å; L918-L959 HydrophobicContact CD1-CD2 4.17Å; L918-L959 HydrophobicContact CD1-CG 4.46Å; L918-I978 HydrophobicContact CD1-CG2 4.43Å
919A96.9Very high95.4Very high0 Ų011 Ų110%06%0.057CC..Hα-helixtrans-62.8-41.5179.300000111.8P865 F915 H916 I917 L922 L923 M974 W977P865-A919 HydrophobicContact CG-CB 3.53Å; F915-A919 WeakPolarHBondContact O-CB 3.31Å; F915-A919 PolarHBondContact O-N 3.47Å; H916-A919 PolarHBondContact O-N 3.42Å; I917-A919 VanDerWaalsContact C-N 3.34Å; I917-A919 PolarHBondContact O-N 3.29Å; A919-L922 PolarHBondContact O-N 3.01Å; A919-L923 VanDerWaalsContact O-CB 3.31Å; A919-L923 WeakPolarHBondContact O-CB 3.34Å; A919-L923 WeakPolarHBondContact O-CG 3.47Å; A919-L923 PolarHBondContact O-N 3.4Å; A919-M974 HydrophobicContact CB-CE 4.16Å; A919-W977 HydrophobicContact CB-CH2 4.29Å; A919-W977 HydrophobicContact CB-CZ3 3.64Å
920L96.4Very high95.4Very high7 Ų716.2 Ų16.24%0.0378%0.076CC..Hα-helixtrans-60.6-45.6173.7-72.8173.2000111.9I748 P865 L882 H916 I917 L922 L923 E924I748-L920 HydrophobicContact CG2-CD1 4.48Å; P865-L920 HydrophobicContact CB-CD2 3.67Å; P865-L920 HydrophobicContact CB-CG 4.19Å; P865-L920 HydrophobicContact CG-CD2 3.97Å; P865-L920 HydrophobicContact CG-CG 4.01Å; L882-L920 HydrophobicContact CD1-CB 4.35Å; H916-L920 WeakPolarHBondContact O-CG 3.22Å; H916-L920 PolarHBondContact O-N 3.43Å; I917-L920 PolarHBondContact O-N 3.04Å; L920-L922 PolarHBondContact O-N 3.26Å; L920-L923 PolarHBondContact O-N 2.94Å; L920-E924 WeakPolarHBondContact O-CB 3.39Å; L920-E924 PolarHBondContact O-N 3.24Å
921G96.4Very high95.1Very high0 Ų022 Ų220%010%0.101CC..Hα-helixtrans-60.7-44.1177.900000113.6I917 L918 E925I917-G921 PolarHBondContact O-N 3.35Å; L918-G921 PolarHBondContact O-N 2.97Å; G921-E925 PolarHBondContact O-N 2.93Å; G921-E925 VanDerWaalsContact O-N 3.15Å
922L96.4Very high94.8Very high0 Ų023.6 Ų23.60%011%0.114CC..Hα-helixtrans-70.1-35.4176.7-65.1168.4000112.8L918 A919 L920 K926 F941 I978 M981 F982 V985L918-L922 WeakPolarHBondContact O-CG 3.39Å; L918-L922 PolarHBondContact O-N 2.85Å; A919-L922 PolarHBondContact O-N 3.01Å; L920-L922 PolarHBondContact O-N 3.26Å; L922-K926 WeakPolarHBondContact O-CB 3.4Å; L922-K926 PolarHBondContact O-N 3.45Å; L922-F941 HydrophobicContact CD2-CD1 4.1Å; L922-F941 HydrophobicContact CD2-CE1 4.2Å; L922-F941 HydrophobicContact CG-CD1 4.28Å; L922-F941 HydrophobicContact CG-CE1 4.02Å; L922-I978 HydrophobicContact CD1-CG2 4.05Å; L922-M981 HydrophobicContact CB-CB 4.43Å; L922-M981 HydrophobicContact CB-CG 3.65Å; L922-M981 HydrophobicContact CD1-CB 4.06Å; L922-M981 HydrophobicContact CD1-CG 4.2Å; L922-F982 HydrophobicContact CD1-CD2 3.62Å; L922-F982 HydrophobicContact CD1-CE2 3.68Å; L922-F982 HydrophobicContact CD1-CG 4.08Å; L922-F982 HydrophobicContact CD1-CZ 4.18Å; L922-F982 HydrophobicContact CD2-CD1 3.94Å; L922-F982 HydrophobicContact CD2-CD2 4.43Å; L922-F982 HydrophobicContact CD2-CE1 3.98Å; L922-F982 HydrophobicContact CD2-CE2 4.48Å; L922-F982 HydrophobicContact CD2-CG 4.15Å; L922-F982 HydrophobicContact CD2-CZ 4.25Å; L922-V985 HydrophobicContact CB-CG2 4.29Å; L922-V985 HydrophobicContact CD2-CG2 4.18Å; L922-V985 WeakPolarHBondContact O-CG2 3.4Å
923L95.2Very high94.3Very high13 Ų1325.6 Ų25.67%0.06813%0.129CC..Hα-helixtrans-68.1-41.5175.7-77.1173.1000111.8P865 A919 L920 K926 Q927 W977 M981P865-L923 HydrophobicContact CB-CD1 4.19Å; P865-L923 HydrophobicContact CG-CD1 3.97Å; P865-L923 WeakPolarHBondContact O-CD1 3.36Å; A919-L923 VanDerWaalsContact O-CB 3.31Å; A919-L923 WeakPolarHBondContact O-CB 3.34Å; A919-L923 WeakPolarHBondContact O-CG 3.47Å; A919-L923 PolarHBondContact O-N 3.4Å; L920-L923 PolarHBondContact O-N 2.94Å; L923-K926 PolarHBondContact O-N 2.9Å; L923-Q927 WeakPolarHBondContact O-CG 3.36Å; L923-Q927 PolarHBondContact O-N 3.49Å; L923-W977 HydrophobicContact CD1-CH2 4.22Å; L923-W977 HydrophobicContact CD2-CH2 4.18Å; L923-W977 HydrophobicContact CG-CH2 4.16Å; L923-M981 HydrophobicContact CD2-CE 3.85Å
924E95Very high93.8Very high15 Ų1527 Ų277%0.0714%0.136CC..Hα-helixtrans-61.6-51177.2-173.265.4-125.300110.6R754 I879 L920 K926 Q927 Q928 F939R754-E924 IonicContact CZ-OE2 2.86Å; R754-E924 VanDerWaalsContact CZ-OE2 3.32Å; R754-E924 IonicContact NH1-OE2 3.73Å; R754-E924 PolarHBondContact NH1-OE2 3.27Å; R754-E924 IonicContact NH2-OE2 3.85Å; R754-E924 PolarHBondContact NH2-OE2 3.35Å; I879-E924 HydrophobicContact CB-CG 4.31Å; I879-E924 HydrophobicContact CD1-CG 4.44Å; I879-E924 HydrophobicContact CG2-CG 4.16Å; L920-E924 WeakPolarHBondContact O-CB 3.39Å; L920-E924 PolarHBondContact O-N 3.24Å; E924-K926 PolarHBondContact O-N 2.84Å; E924-Q927 PolarHBondContact O-N 2.93Å; E924-Q928 WeakPolarHBondContact O-CG 3.27Å; E924-Q928 PolarHBondContact O-N 3.21Å; E924-Q928 VanDerWaalsContact O-N 3.09Å; E924-Q928 PolarHBondContact OE1-NE2 2.91Å; E924-F939 HydrophobicContact CB-CE1 4.01Å; E924-F939 HydrophobicContact CB-CZ 4.42Å; E924-F939 HydrophobicContact CG-CD1 4.39Å; E924-F939 HydrophobicContact CG-CE1 3.92Å; E924-F939 HydrophobicContact CG-CZ 4.1Å
925E94.8Very high93.2Very high0 Ų033.4 Ų33.40%017%0.166CC..Hα-helixtrans-62.2-42.4176.4-171.8170.5-175.700112.2G921 Q927 Q928 L929 F939 F941 Y942 V985 R989G921-E925 PolarHBondContact O-N 2.93Å; G921-E925 VanDerWaalsContact O-N 3.15Å; E925-Q927 PolarHBondContact O-N 3.25Å; E925-Q928 PolarHBondContact O-N 3.37Å; E925-L929 HydrophobicContact CG-CD1 3.85Å; E925-L929 HydrophobicContact CG-CG 4.34Å; E925-L929 WeakPolarHBondContact O-CB 3.49Å; E925-L929 WeakPolarHBondContact O-CG 3.49Å; E925-L929 PolarHBondContact O-N 3.24Å; E925-F939 HydrophobicContact CB-CD1 3.8Å; E925-F939 HydrophobicContact CB-CE1 4.11Å; E925-F939 VanDerWaalsContact CD-O 3.25Å; E925-F939 HydrophobicContact CG-CD1 4.36Å; E925-F939 WeakPolarHBondContact CG-O 3.24Å; E925-F941 PolarHBondContact OE2-N 3.21Å; E925-Y942 WeakPolarHBondContact OE2-CB 3.35Å; E925-Y942 PolarHBondContact OE2-N 2.94Å; E925-V985 HydrophobicContact CB-CG1 4.34Å; E925-V985 HydrophobicContact CG-CG1 3.88Å; E925-R989 IonicContact OE1-CZ 2.74Å; E925-R989 VanDerWaalsContact OE1-CZ 3.25Å; E925-R989 IonicContact OE1-NE 3.79Å; E925-R989 PolarHBondContact OE1-NE 2.56Å; E925-R989 IonicContact OE1-NH2 3.72Å; E925-R989 PolarHBondContact OE1-NH2 3.33Å
926K94.6Very high92.7Very high50 Ų5039.8 Ų39.822%0.21720%0.196CC..Hα-helixtrans-57.6-46.1174.4173179.4168.7-168.60111.7L922 L923 E924 Q928 L929 Q930 M981 T984 V985 L988L922-K926 WeakPolarHBondContact O-CB 3.4Å; L922-K926 PolarHBondContact O-N 3.45Å; L923-K926 PolarHBondContact O-N 2.9Å; E924-K926 PolarHBondContact O-N 2.84Å; K926-Q928 VanDerWaalsContact C-N 3.34Å; K926-Q928 PolarHBondContact O-N 2.79Å; K926-L929 PolarHBondContact O-N 3.45Å; K926-Q930 WeakPolarHBondContact O-CB 3.35Å; K926-Q930 VanDerWaalsContact O-CG 3.23Å; K926-Q930 WeakPolarHBondContact O-CG 3Å; K926-Q930 PolarHBondContact O-N 2.92Å; K926-M981 HydrophobicContact CD-CE 4.46Å; K926-M981 HydrophobicContact CD-SD 3.6Å; K926-M981 VanDerWaalsContact CD-SD 3.6Å; K926-T984 HydrophobicContact CD-CG2 4.38Å; K926-V985 HydrophobicContact CB-CG2 4.03Å; K926-L988 HydrophobicContact CB-CD1 4.47Å; K926-L988 HydrophobicContact CG-CD1 3.92Å
927Q92.9Very high92.3Very high26 Ų2640.1 Ų40.112%0.12120%0.198CC..Hα-helixtrans-61.9-43.3179.5-78-168.230.300111.3P868 L923 E924 E925 Q930 K931P868-Q927 PolarHBondContact O-NE2 3.35Å; L923-Q927 WeakPolarHBondContact O-CG 3.36Å; L923-Q927 PolarHBondContact O-N 3.49Å; E924-Q927 PolarHBondContact O-N 2.93Å; E925-Q927 PolarHBondContact O-N 3.25Å; Q927-Q930 PolarHBondContact O-N 3.29Å; Q927-K931 VanDerWaalsContact O-CG 3.3Å; Q927-K931 WeakPolarHBondContact O-CG 3.25Å; Q927-K931 PolarHBondContact O-N 3.22Å
928Q92.6Very high91.9Very high44 Ų4446.3 Ų46.321%0.20624%0.236CC..Hα-helixtrans-65.5-46.2180-65.917825.500111.2E924 E925 K926 Q930 K931 A932 V937 F939E924-Q928 WeakPolarHBondContact O-CG 3.27Å; E924-Q928 PolarHBondContact O-N 3.21Å; E924-Q928 VanDerWaalsContact O-N 3.09Å; E924-Q928 PolarHBondContact OE1-NE2 2.91Å; E925-Q928 PolarHBondContact O-N 3.37Å; K926-Q928 VanDerWaalsContact C-N 3.34Å; K926-Q928 PolarHBondContact O-N 2.79Å; Q928-Q930 PolarHBondContact O-N 2.94Å; Q928-K931 PolarHBondContact O-N 3.49Å; Q928-A932 PolarHBondContact O-N 3.2Å; Q928-V937 HydrophobicContact CB-CG1 3.69Å; Q928-V937 HydrophobicContact CB-CG2 4.06Å; Q928-F939 VanDerWaalsContact OE1-CB 3.26Å
929L92.5Very high91.7Very high20 Ų2046.5 Ų46.511%0.10524%0.237CC..Hα-helixtrans-65-14.5174.1-69.3170.6000114.6E925 K926 E934 V937 V985 L988 R989E925-L929 HydrophobicContact CG-CD1 3.85Å; E925-L929 HydrophobicContact CG-CG 4.34Å; E925-L929 WeakPolarHBondContact O-CB 3.49Å; E925-L929 WeakPolarHBondContact O-CG 3.49Å; E925-L929 PolarHBondContact O-N 3.24Å; K926-L929 PolarHBondContact O-N 3.45Å; L929-E934 HydrophobicContact CD2-CG 4.12Å; L929-V937 HydrophobicContact CD2-CB 3.92Å; L929-V937 HydrophobicContact CD2-CG1 4.11Å; L929-V937 HydrophobicContact CD2-CG2 4.03Å; L929-V937 HydrophobicContact CG-CB 4.48Å; L929-V937 HydrophobicContact CG-CG1 4.18Å; L929-V937 HydrophobicContact CG-CG2 4.48Å; L929-V985 HydrophobicContact CD1-CG1 4.08Å; L929-L988 HydrophobicContact CB-CB 4.11Å; L929-L988 HydrophobicContact CB-CD1 4.38Å; L929-L988 HydrophobicContact CD1-CB 3.91Å; L929-R989 HydrophobicContact CD1-CG 3.89Å
930Q91.8Very high91.5Very high127 Ų12748.2 Ų48.259%0.59325%0.246SC*.Hα-helixtrans-92.3-16.1172.5-74.1-175.8-62.500113.1K926 Q927 Q928 L988K926-Q930 WeakPolarHBondContact O-CB 3.35Å; K926-Q930 VanDerWaalsContact O-CG 3.23Å; K926-Q930 WeakPolarHBondContact O-CG 3Å; K926-Q930 PolarHBondContact O-N 2.92Å; Q927-Q930 PolarHBondContact O-N 3.29Å; Q928-Q930 PolarHBondContact O-N 2.94Å; Q930-L988 HydrophobicContact CG-CD1 4.23Å
931K89.3Confident91.4Very high122 Ų12247.9 Ų47.953%0.5324%0.244SC..Hα-helixtrans-103.9-33.3-176.9-71.2170-176.4174.50113E870 Q927 Q928E870-K931 IonicContact OE1-NZ 3.37Å; E870-K931 PolarHBondContact OE1-NZ 3.06Å; Q927-K931 VanDerWaalsContact O-CG 3.3Å; Q927-K931 WeakPolarHBondContact O-CG 3.25Å; Q927-K931 PolarHBondContact O-N 3.22Å; Q928-K931 PolarHBondContact O-N 3.49Å
932A88.1Confident91.2Very high33 Ų3349.2 Ų49.227%0.27325%0.249SC..SBendtrans-127.5158.6-176.500000112Q928 E936 V937Q928-A932 PolarHBondContact O-N 3.2Å; A932-E936 HydrophobicContact CB-CB 4.31Å; A932-V937 HydrophobicContact CB-CG2 4.05Å
933P85.6Confident91Very high64 Ų6453.2 Ų53.242%0.41627%0.268SS..  trans-54.8154.5168.6-22.934000112.7E935 E936 V937P933-E935 WeakPolarHBondContact CB-OE2 3.35Å; P933-E935 PolarHBondContact O-N 3.38Å; P933-E936 HydrophobicContact CB-CG 4.48Å; P933-E936 HydrophobicContact CG-CG 4.49Å; P933-E936 PolarHBondContact O-N 3.3Å; P933-E936 VanDerWaalsContact O-N 3.14Å; P933-V937 PolarHBondContact O-N 3.4Å
934E86.3Confident90.8Very high40 Ų4054.4 Ų54.419%0.18727%0.272CS..G310 helixtrans-58.8-38.9-176.9-166-156.1171.600111.7L929 E936 V937 R989 S992L929-E934 HydrophobicContact CD2-CG 4.12Å; E934-E936 PolarHBondContact O-N 3.03Å; E934-V937 PolarHBondContact O-N 3.45Å; E934-V937 VanDerWaalsContact O-N 3.15Å; E934-R989 VanDerWaalsContact CD-O 3.27Å; E934-R989 PolarHBondContact O-NH1 2.84Å; E934-R989 WeakPolarHBondContact OE1-CD 3.14Å; E934-S992 WeakPolarHBondContact OE2-CB 3.26Å
935E83.7Confident90.7Very high136 Ų13653.7 Ų53.764%0.63627%0.269SS*.G310 helixtrans-65.3-22.1-177-57.885.3169.500113P933P933-E935 WeakPolarHBondContact CB-OE2 3.35Å; P933-E935 PolarHBondContact O-N 3.38Å
936E87.1Confident90.4Very high134 Ų13455 Ų5563%0.62628%0.278SS*.G310 helixtrans-92.5-19.2177.7-63.9-179.5-16900112.3A932 P933 E934 T938A932-E936 HydrophobicContact CB-CB 4.31Å; P933-E936 HydrophobicContact CB-CG 4.48Å; P933-E936 HydrophobicContact CG-CG 4.49Å; P933-E936 PolarHBondContact O-N 3.3Å; P933-E936 VanDerWaalsContact O-N 3.14Å; E934-E936 PolarHBondContact O-N 3.03Å; E936-T938 PolarHBondContact O-N 3.25Å; E936-T938 VanDerWaalsContact O-N 3.12Å
937V88.1Confident90.1Very high10 Ų1059 Ų596%0.06129%0.292CS..  trans-86.588.5-175.7-176.70000111.6Q928 L929 A932 P933 E934 F939 R989Q928-V937 HydrophobicContact CB-CG1 3.69Å; Q928-V937 HydrophobicContact CB-CG2 4.06Å; L929-V937 HydrophobicContact CD2-CB 3.92Å; L929-V937 HydrophobicContact CD2-CG1 4.11Å; L929-V937 HydrophobicContact CD2-CG2 4.03Å; L929-V937 HydrophobicContact CG-CB 4.48Å; L929-V937 HydrophobicContact CG-CG1 4.18Å; L929-V937 HydrophobicContact CG-CG2 4.48Å; A932-V937 HydrophobicContact CB-CG2 4.05Å; P933-V937 PolarHBondContact O-N 3.4Å; E934-V937 PolarHBondContact O-N 3.45Å; E934-V937 VanDerWaalsContact O-N 3.15Å; V937-F939 VanDerWaalsContact C-N 3.27Å; V937-F939 PolarHBondContact O-N 3.39Å; V937-R989 PolarHBondContact O-NH1 3.28Å; V937-R989 PolarHBondContact O-NH2 3.11Å; V937-R989 VanDerWaalsContact O-NH2 3.08Å
938T89.3Confident89.5Confident131 Ų13163.5 Ų63.580%0.80432%0.316SS*.  trans-70.4-12.3178.458.70000115.2E936 D940E936-T938 PolarHBondContact O-N 3.25Å; E936-T938 VanDerWaalsContact O-N 3.12Å; T938-D940 PolarHBondContact O-N 2.83Å
939F92.9Very high88.5Confident4 Ų462.4 Ų62.42%0.01832%0.316CS..  trans-81.395.6-177.6-173-100.6000111.7I879 L882 N883 E924 E925 Q928 V937 F941 R989I879-F939 HydrophobicContact CB-CE2 4.18Å; I879-F939 HydrophobicContact CD1-CD2 4.11Å; I879-F939 HydrophobicContact CD1-CE2 4.35Å; I879-F939 HydrophobicContact CG1-CD2 4.21Å; I879-F939 HydrophobicContact CG1-CE2 4.07Å; I879-F939 WeakPolarHBondContact O-CE2 3.21Å; L882-F939 HydrophobicContact CB-CZ 4.18Å; L882-F939 HydrophobicContact CD1-CZ 4.43Å; N883-F939 HydrophobicContact CB-CD2 4.22Å; N883-F939 HydrophobicContact CB-CE2 3.67Å; N883-F939 HydrophobicContact CB-CZ 4.14Å; E924-F939 HydrophobicContact CB-CE1 4.01Å; E924-F939 HydrophobicContact CB-CZ 4.42Å; E924-F939 HydrophobicContact CG-CD1 4.39Å; E924-F939 HydrophobicContact CG-CE1 3.92Å; E924-F939 HydrophobicContact CG-CZ 4.1Å; E925-F939 HydrophobicContact CB-CD1 3.8Å; E925-F939 HydrophobicContact CB-CE1 4.11Å; E925-F939 VanDerWaalsContact CD-O 3.25Å; E925-F939 HydrophobicContact CG-CD1 4.36Å; E925-F939 WeakPolarHBondContact CG-O 3.24Å; Q928-F939 VanDerWaalsContact OE1-CB 3.26Å; V937-F939 VanDerWaalsContact C-N 3.27Å; V937-F939 PolarHBondContact O-N 3.39Å; F939-F941 HydrophobicContact CD1-CB 4.17Å; F939-F941 HydrophobicContact CE1-CB 3.59Å; F939-F941 HydrophobicContact CE1-CG 4.41Å; F939-F941 HydrophobicContact CZ-CB 4.04Å; F939-F941 PolarHBondContact O-N 3.36Å; F939-R989 PolarHBondContact O-NH2 3.34Å
940D92.1Very high87.3Confident37 Ų3767.2 Ų67.220%0.19835%0.352CS..  trans-95.433.9-168.879.3-42.4000115.8N883 T938 Y942 H943 K944 R947N883-D940 PolarHBondContact ND2-N 2.63Å; N883-D940 PolarHBondContact ND2-OD1 3.21Å; T938-D940 PolarHBondContact O-N 2.83Å; D940-Y942 VanDerWaalsContact C-N 3.34Å; D940-Y942 PolarHBondContact O-N 3.25Å; D940-H943 HydrophobicContact CB-CB 4.32Å; D940-H943 PolarHBondContact O-N 3.22Å; D940-K944 PolarHBondContact O-N 3.08Å; D940-K944 VanDerWaalsContact OD1-CE 3.24Å; D940-K944 WeakPolarHBondContact OD1-CE 3.19Å; D940-R947 IonicContact OD2-NH2 2.63Å; D940-R947 PolarHBondContact OD2-NH2 2.83Å; D940-R947 VanDerWaalsContact OD2-NH2 3.09Å
941F94.7Very high85.9Confident0 Ų063.6 Ų63.60%034%0.34CS..Hα-helixtrans-52.6-46.3-173-179.6-88.6000113.6L882 N883 M888 L918 L922 E925 F939 H943 K944 A945L882-F941 HydrophobicContact CB-CD2 4.14Å; L882-F941 HydrophobicContact CB-CE2 4.17Å; L882-F941 WeakPolarHBondContact O-CD2 3.35Å; L882-F941 VanDerWaalsContact O-CE2 3.23Å; L882-F941 WeakPolarHBondContact O-CE2 3.3Å; N883-F941 WeakPolarHBondContact OD1-CA 3.37Å; M888-F941 HydrophobicContact CE-CD2 3.46Å; M888-F941 VanDerWaalsContact CE-CD2 3.46Å; M888-F941 HydrophobicContact CE-CE2 3.4Å; M888-F941 HydrophobicContact CE-CG 4.17Å; M888-F941 HydrophobicContact CE-CZ 4.05Å; L918-F941 HydrophobicContact CD2-CE1 4.41Å; L918-F941 HydrophobicContact CD2-CZ 3.95Å; L922-F941 HydrophobicContact CD2-CD1 4.1Å; L922-F941 HydrophobicContact CD2-CE1 4.2Å; L922-F941 HydrophobicContact CG-CD1 4.28Å; L922-F941 HydrophobicContact CG-CE1 4.02Å; E925-F941 PolarHBondContact OE2-N 3.21Å; F939-F941 HydrophobicContact CD1-CB 4.17Å; F939-F941 HydrophobicContact CE1-CB 3.59Å; F939-F941 HydrophobicContact CE1-CG 4.41Å; F939-F941 HydrophobicContact CZ-CB 4.04Å; F939-F941 PolarHBondContact O-N 3.36Å; F941-H943 VanDerWaalsContact C-N 3.34Å; F941-H943 PolarHBondContact O-N 3.38Å; F941-K944 PolarHBondContact O-N 3.34Å; F941-A945 HydrophobicContact CE1-CB 4.42Å; F941-A945 WeakPolarHBondContact O-CB 2.98Å; F941-A945 PolarHBondContact O-N 3.44Å
942Y93.6Very high85.3Confident27 Ų2761 Ų6111%0.10634%0.342CS..Hα-helixtrans-52.1-51.2174.1167.6-99.4000111.2E925 D940 K944 A945 S946 F982 V985 K986E925-Y942 WeakPolarHBondContact OE2-CB 3.35Å; E925-Y942 PolarHBondContact OE2-N 2.94Å; D940-Y942 VanDerWaalsContact C-N 3.34Å; D940-Y942 PolarHBondContact O-N 3.25Å; Y942-K944 PolarHBondContact O-N 2.98Å; Y942-A945 PolarHBondContact O-N 2.83Å; Y942-S946 WeakPolarHBondContact O-CB 3.43Å; Y942-S946 PolarHBondContact O-N 3.44Å; Y942-S946 PolarHBondContact O-OG 3.26Å; Y942-F982 AromaticContact CD2-CD1 3.71Å; Y942-F982 HydrophobicContact CD2-CD1 3.71Å; Y942-F982 HydrophobicContact CD2-CE1 4.32Å; Y942-F982 AromaticContact CE2-CD1 3.94Å; Y942-F982 HydrophobicContact CE2-CD1 3.94Å; Y942-V985 HydrophobicContact CD2-CG1 4.44Å; Y942-V985 HydrophobicContact CG-CG1 4.13Å; Y942-K986 HydrophobicContact CE1-CB 4.44Å; Y942-K986 HydrophobicContact CE2-CB 3.82Å; Y942-K986 HydrophobicContact CE2-CG 4.47Å; Y942-K986 WeakPolarHBondContact OH-CD 3.5Å; Y942-K986 WeakPolarHBondContact OH-CG 3.41Å
943H91.1Very high85.2Confident84 Ų8460.7 Ų60.739%0.38934%0.335SS..Hα-helixtrans-63.7-41.9-179.3-68.8-70.6000111.7D940 F941 S946 R947D940-H943 HydrophobicContact CB-CB 4.32Å; D940-H943 PolarHBondContact O-N 3.22Å; F941-H943 VanDerWaalsContact C-N 3.34Å; F941-H943 PolarHBondContact O-N 3.38Å; H943-S946 PolarHBondContact O-N 3.08Å; H943-R947 WeakPolarHBondContact O-CG 3.29Å; H943-R947 PolarHBondContact O-N 2.7Å; H943-R947 VanDerWaalsContact O-N 3.13Å
944K91.4Very high85.4Confident38 Ų3858.8 Ų58.817%0.16532%0.321CS..Hα-helixtrans-67.1-39.7177.4-65.2-150.6-166.2-178.10113.3N883 D885 M888 R892 D940 F941 Y942 S946 R947N883-K944 WeakPolarHBondContact O-CD 3.36Å; N883-K944 WeakPolarHBondContact O-CE 3.41Å; N883-K944 PolarHBondContact O-NZ 3.11Å; N883-K944 WeakPolarHBondContact OD1-CD 3.45Å; N883-K944 WeakPolarHBondContact OD1-CE 3.36Å; N883-K944 WeakPolarHBondContact OD1-CG 3.39Å; D885-K944 IonicContact OD1-NZ 3.4Å; M888-K944 HydrophobicContact CE-CB 3.8Å; M888-K944 HydrophobicContact CG-CB 4.26Å; M888-K944 HydrophobicContact SD-CB 4.08Å; R892-K944 PolarHBondContact NH2-O 3.27Å; D940-K944 PolarHBondContact O-N 3.08Å; D940-K944 VanDerWaalsContact OD1-CE 3.24Å; D940-K944 WeakPolarHBondContact OD1-CE 3.19Å; F941-K944 PolarHBondContact O-N 3.34Å; Y942-K944 PolarHBondContact O-N 2.98Å; K944-S946 VanDerWaalsContact C-N 3.3Å; K944-S946 PolarHBondContact O-N 2.97Å; K944-R947 PolarHBondContact O-N 2.95Å
945A91.9Very high85.7Confident0 Ų056.9 Ų56.90%031%0.312CS..Hα-helixtrans-65.2-34.4174.700000112.2M888 R892 F941 Y942 I955 F982M888-A945 HydrophobicContact CE-CB 4.41Å; M888-A945 HydrophobicContact SD-CB 4.23Å; R892-A945 PolarHBondContact NH2-O 3.43Å; F941-A945 HydrophobicContact CE1-CB 4.42Å; F941-A945 WeakPolarHBondContact O-CB 2.98Å; F941-A945 PolarHBondContact O-N 3.44Å; Y942-A945 PolarHBondContact O-N 2.83Å; A945-I955 HydrophobicContact CB-CB 4.4Å; A945-I955 HydrophobicContact CB-CD1 4.1Å; A945-I955 PolarHBondContact O-N 3.27Å; A945-I955 VanDerWaalsContact O-N 3.13Å; A945-F982 HydrophobicContact CB-CE1 3.81Å; A945-F982 HydrophobicContact CB-CZ 3.91Å
946S89.9Confident86Confident27 Ų2752.2 Ų52.219%0.18929%0.291CS..Hα-helixtrans-79.4-13.7177.5-61.90000115.2Y942 H943 K944 N954Y942-S946 WeakPolarHBondContact O-CB 3.43Å; Y942-S946 PolarHBondContact O-N 3.44Å; Y942-S946 PolarHBondContact O-OG 3.26Å; H943-S946 PolarHBondContact O-N 3.08Å; K944-S946 VanDerWaalsContact C-N 3.3Å; K944-S946 PolarHBondContact O-N 2.97Å; S946-N954 WeakPolarHBondContact O-CB 3.33Å; S946-N954 PolarHBondContact O-ND2 3.31Å
947R87.6Confident86.2Confident135 Ų13549.3 Ų49.351%0.50928%0.278SS..SBendtrans-62.3146.6174-74.2169.1-157.1-1668.1111.2R892 D940 H943 K944 N954R892-R947 VanDerWaalsContact CZ-O 3.26Å; R892-R947 PolarHBondContact NH1-O 3.32Å; R892-R947 PolarHBondContact NH2-O 3.06Å; D940-R947 IonicContact OD2-NH2 2.63Å; D940-R947 PolarHBondContact OD2-NH2 2.83Å; D940-R947 VanDerWaalsContact OD2-NH2 3.09Å; H943-R947 WeakPolarHBondContact O-CG 3.29Å; H943-R947 PolarHBondContact O-N 2.7Å; H943-R947 VanDerWaalsContact O-N 3.13Å; K944-R947 PolarHBondContact O-N 2.95Å; R947-N954 WeakPolarHBondContact O-CB 3.49Å
948L81.1Confident86.5Confident121 Ų12149 Ų4963%0.63428%0.276SS*.  trans-69.2137173.5-62.7174.5000110.6
949G70.1Confident86.7Confident20 Ų2042.7 Ų42.721%0.20624%0.237CC..  trans-89.7-175.717500000112.7R892 S951 A952 M953R892-G949 VanDerWaalsContact NH1-N 3.14Å; G949-S951 PolarHBondContact O-N 2.91Å; G949-A952 PolarHBondContact O-N 3.29Å; G949-M953 PolarHBondContact N-O 3Å
950S67.2Low86.6Confident121 Ų12147.9 Ų47.985%0.84626%0.262SS*.THydrogen-bonded Turntrans-56.9-31.517343.10000113.2A952S950-A952 PolarHBondContact O-N 3.37Å
951S63.8Low86.6Confident51 Ų5151.2 Ų51.236%0.35727%0.274SS..THydrogen-bonded Turntrans-75.91.7174.359.30000114.8E896 G949 M953E896-S951 WeakPolarHBondContact OE1-CB 3.29Å; E896-S951 PolarHBondContact OE1-OG 2.94Å; G949-S951 PolarHBondContact O-N 2.91Å; S951-M953 PolarHBondContact O-N 3.09Å; S951-M953 PolarHBondContact OG-N 3Å
952A76.7Confident86.4Confident68 Ų6851.2 Ų51.256%0.56227%0.274SS*.SBendtrans56.422.6-168.200000114.6G949 S950G949-A952 PolarHBondContact O-N 3.29Å; S950-A952 PolarHBondContact O-N 3.37Å
953M84.7Confident86.2Confident27 Ų2753.8 Ų53.813%0.13329%0.286CS..  trans-115.3150.9171.4-58.6-159.172.300111.1R892 G949 S951 M957 L958 K961R892-M953 PolarHBondContact NH1-O 3.35Å; G949-M953 PolarHBondContact N-O 3Å; S951-M953 PolarHBondContact O-N 3.09Å; S951-M953 PolarHBondContact OG-N 3Å; M953-M957 HydrophobicContact CE-CB 3.6Å; M953-M957 HydrophobicContact CE-CE 4.04Å; M953-L958 HydrophobicContact CB-CD2 3.95Å; M953-L958 HydrophobicContact CB-CG 4.16Å; M953-L958 HydrophobicContact CE-CD2 4.46Å; M953-L958 HydrophobicContact CG-CD2 4.49Å; M953-L958 HydrophobicContact SD-CD2 3.93Å; M953-K961 HydrophobicContact CE-CD 3.76Å; M953-K961 VanDerWaalsContact CE-CE 3.48Å; M953-K961 HydrophobicContact CE-CG 4.43Å; M953-K961 HydrophobicContact SD-CD 4.13Å; M953-K961 PolarHBondContact SD-NZ 3.29Å
954N89.8Confident85.9Confident23 Ų2352.7 Ų52.712%0.12330%0.298CS..  trans-104169.3167.973.818.5000110.9S946 R947 Q956 M957 L958S946-N954 WeakPolarHBondContact O-CB 3.33Å; S946-N954 PolarHBondContact O-ND2 3.31Å; R947-N954 WeakPolarHBondContact O-CB 3.49Å; N954-Q956 VanDerWaalsContact C-N 3.27Å; N954-Q956 PolarHBondContact O-N 3Å; N954-Q956 PolarHBondContact OD1-N 3.36Å; N954-M957 PolarHBondContact O-N 3.39Å; N954-M957 VanDerWaalsContact OD1-CG 3.24Å; N954-M957 WeakPolarHBondContact OD1-CG 3.28Å; N954-M957 PolarHBondContact OD1-N 3.32Å; N954-L958 WeakPolarHBondContact O-CG 3.41Å; N954-L958 PolarHBondContact O-N 2.88Å
955I92.2Very high85.7Confident0 Ų051.9 Ų51.90%030%0.295CS..Hα-helixtrans-61.1-37.4-174.6-65.1-177.5000111.5M888 L891 R892 F895 L918 A945 M957 L958 L959 F982M888-I955 HydrophobicContact SD-CD1 4.03Å; L891-I955 HydrophobicContact CB-CD1 4.32Å; R892-I955 HydrophobicContact CG-CD1 4.17Å; R892-I955 HydrophobicContact CG-CG1 3.79Å; F895-I955 HydrophobicContact CD2-CG2 4.26Å; F895-I955 HydrophobicContact CE2-CG2 4.03Å; L918-I955 HydrophobicContact CD1-CG2 3.71Å; L918-I955 HydrophobicContact CD2-CD1 4.14Å; L918-I955 HydrophobicContact CD2-CG2 3.87Å; L918-I955 HydrophobicContact CG-CG2 4.46Å; A945-I955 HydrophobicContact CB-CB 4.4Å; A945-I955 HydrophobicContact CB-CD1 4.1Å; A945-I955 PolarHBondContact O-N 3.27Å; A945-I955 VanDerWaalsContact O-N 3.13Å; I955-M957 PolarHBondContact O-N 3.13Å; I955-L958 PolarHBondContact O-N 2.8Å; I955-L959 HydrophobicContact CG2-CD1 4.21Å; I955-L959 HydrophobicContact CG2-CG 4.38Å; I955-L959 WeakPolarHBondContact O-CG 3.25Å; I955-L959 PolarHBondContact O-N 2.82Å; I955-F982 HydrophobicContact CG2-CZ 4.39Å
956Q91.1Very high85.4Confident39 Ų3956.7 Ų56.718%0.18233%0.326CS..Hα-helixtrans-62.1-44.6177.6-174.5169.8-6.600112.2N954 L958 L959 E960 L979N954-Q956 VanDerWaalsContact C-N 3.27Å; N954-Q956 PolarHBondContact O-N 3Å; N954-Q956 PolarHBondContact OD1-N 3.36Å; Q956-L958 VanDerWaalsContact C-N 3.32Å; Q956-L958 PolarHBondContact O-N 3.47Å; Q956-L959 PolarHBondContact O-N 3.18Å; Q956-E960 WeakPolarHBondContact O-CG 3.32Å; Q956-E960 PolarHBondContact O-N 3.44Å; Q956-L979 HydrophobicContact CG-CD2 3.8Å
957M91.9Very high85Confident73 Ų7361 Ų6136%0.3634%0.343SS..Hα-helixtrans-67.3-30.5175.8-62.7164.570.500112.8M953 N954 I955 K961M953-M957 HydrophobicContact CE-CB 3.6Å; M953-M957 HydrophobicContact CE-CE 4.04Å; N954-M957 PolarHBondContact O-N 3.39Å; N954-M957 VanDerWaalsContact OD1-CG 3.24Å; N954-M957 WeakPolarHBondContact OD1-CG 3.28Å; N954-M957 PolarHBondContact OD1-N 3.32Å; I955-M957 PolarHBondContact O-N 3.13Å; M957-K961 PolarHBondContact O-N 2.98Å
958L92.5Very high84.9Confident2 Ų254.7 Ų54.71%0.0132%0.319CS..Hα-helixtrans-68.4-45.1173.2-64.3169.5000110.4R892 F895 E896 I899 M953 N954 I955 Q956 E960 K961 L962R892-L958 HydrophobicContact CG-CD1 4.46Å; F895-L958 HydrophobicContact CB-CB 4.15Å; F895-L958 HydrophobicContact CB-CD1 4.15Å; E896-L958 HydrophobicContact CG-CD1 4.07Å; E896-L958 HydrophobicContact CG-CD2 3.85Å; I899-L958 HydrophobicContact CD1-CB 4.14Å; I899-L958 HydrophobicContact CD1-CD2 3.44Å; I899-L958 VanDerWaalsContact CD1-CD2 3.44Å; I899-L958 HydrophobicContact CD1-CG 4.4Å; M953-L958 HydrophobicContact CB-CD2 3.95Å; M953-L958 HydrophobicContact CB-CG 4.16Å; M953-L958 HydrophobicContact CE-CD2 4.46Å; M953-L958 HydrophobicContact CG-CD2 4.49Å; M953-L958 HydrophobicContact SD-CD2 3.93Å; N954-L958 WeakPolarHBondContact O-CG 3.41Å; N954-L958 PolarHBondContact O-N 2.88Å; I955-L958 PolarHBondContact O-N 2.8Å; Q956-L958 VanDerWaalsContact C-N 3.32Å; Q956-L958 PolarHBondContact O-N 3.47Å; L958-E960 PolarHBondContact O-N 2.94Å; L958-K961 PolarHBondContact O-N 3.43Å; L958-K961 VanDerWaalsContact O-N 3.16Å; L958-L962 WeakPolarHBondContact O-CG 3.39Å; L958-L962 PolarHBondContact O-N 3.48Å
959L93.6Very high85.2Confident0 Ų054.3 Ų54.30%032%0.315CS..Hα-helixtrans-59.3-41.4175.3-70.3171.3000112.9F915 L918 I955 Q956 K961 L962 K963 I975 I978 L979 F982F915-L959 HydrophobicContact CD1-CD2 3.86Å; F915-L959 HydrophobicContact CE1-CD2 3.51Å; L918-L959 HydrophobicContact CD1-CD1 4.02Å; L918-L959 HydrophobicContact CD1-CD2 4.17Å; L918-L959 HydrophobicContact CD1-CG 4.46Å; I955-L959 HydrophobicContact CG2-CD1 4.21Å; I955-L959 HydrophobicContact CG2-CG 4.38Å; I955-L959 WeakPolarHBondContact O-CG 3.25Å; I955-L959 PolarHBondContact O-N 2.82Å; Q956-L959 PolarHBondContact O-N 3.18Å; L959-K961 VanDerWaalsContact C-N 3.32Å; L959-K961 PolarHBondContact O-N 3Å; L959-L962 PolarHBondContact O-N 3.49Å; L959-K963 PolarHBondContact O-N 2.63Å; L959-I975 HydrophobicContact CB-CG2 4.18Å; L959-I975 HydrophobicContact CD2-CG2 4.41Å; L959-I975 WeakPolarHBondContact O-CG2 3.32Å; L959-I978 HydrophobicContact CD1-CG2 3.61Å; L959-L979 HydrophobicContact CB-CD2 4.04Å; L959-L979 HydrophobicContact CB-CG 4.48Å; L959-L979 HydrophobicContact CD1-CD2 4.28Å; L959-F982 HydrophobicContact CD1-CD2 4.39Å; L959-F982 HydrophobicContact CD1-CE2 3.82Å
960E92Very high85.9Confident113 Ų11356 Ų5653%0.52833%0.331SS..Hα-helixtrans-60.8-39.1175.1-74.7176.8-176.200112.5Q956 L958 L979Q956-E960 WeakPolarHBondContact O-CG 3.32Å; Q956-E960 PolarHBondContact O-N 3.44Å; L958-E960 PolarHBondContact O-N 2.94Å; E960-L979 HydrophobicContact CG-CD1 4.33Å; E960-L979 HydrophobicContact CG-CD2 4.32Å
961K91.4Very high87Confident107 Ų10750.7 Ų50.747%0.46529%0.293SS..Hα-helixtrans-67.9-47172.9-76.6-174.2173.8177.30112.2I899 M953 M957 L958 L959 K963 G964I899-K961 HydrophobicContact CD1-CB 3.91Å; I899-K961 HydrophobicContact CD1-CD 4.11Å; I899-K961 HydrophobicContact CG1-CB 4.24Å; I899-K961 HydrophobicContact CG2-CD 4.24Å; M953-K961 HydrophobicContact CE-CD 3.76Å; M953-K961 VanDerWaalsContact CE-CE 3.48Å; M953-K961 HydrophobicContact CE-CG 4.43Å; M953-K961 HydrophobicContact SD-CD 4.13Å; M953-K961 PolarHBondContact SD-NZ 3.29Å; M957-K961 PolarHBondContact O-N 2.98Å; L958-K961 PolarHBondContact O-N 3.43Å; L958-K961 VanDerWaalsContact O-N 3.16Å; L959-K961 VanDerWaalsContact C-N 3.32Å; L959-K961 PolarHBondContact O-N 3Å; K961-K963 PolarHBondContact O-N 2.97Å; K961-G964 PolarHBondContact O-N 3.44Å
962L91.3Very high88.3Confident0 Ų051 Ų510%029%0.288CS..Hα-helixtrans-57.9-36.1179.4-69.6171.4000112.1F895 A898 I899 L911 F915 L958 L959 G964 I965 L968 I975F895-L962 HydrophobicContact CB-CD1 3.95Å; F895-L962 HydrophobicContact CD1-CD1 3.57Å; F895-L962 HydrophobicContact CE1-CD1 4.42Å; F895-L962 HydrophobicContact CG-CD1 3.99Å; A898-L962 HydrophobicContact CB-CD2 3.74Å; I899-L962 HydrophobicContact CD1-CG 4.42Å; I899-L962 HydrophobicContact CG1-CD2 3.73Å; I899-L962 HydrophobicContact CG1-CG 4.11Å; L911-L962 HydrophobicContact CD2-CD1 4.5Å; F915-L962 HydrophobicContact CE1-CD1 4.11Å; F915-L962 HydrophobicContact CZ-CD1 4.27Å; L958-L962 WeakPolarHBondContact O-CG 3.39Å; L958-L962 PolarHBondContact O-N 3.48Å; L959-L962 PolarHBondContact O-N 3.49Å; L962-G964 PolarHBondContact O-N 3.43Å; L962-G964 VanDerWaalsContact O-N 3.14Å; L962-I965 HydrophobicContact CD2-CD1 3.82Å; L962-I965 WeakPolarHBondContact O-CB 3.48Å; L962-I965 PolarHBondContact O-N 3.21Å; L962-L968 HydrophobicContact CB-CD1 4.14Å; L962-L968 HydrophobicContact CD2-CD1 3.87Å; L962-I975 HydrophobicContact CB-CD1 4.25Å
963K89.6Confident89.1Confident81 Ų8151 Ų5135%0.35228%0.279SS..THydrogen-bonded Turntrans-59.1-22.4174.5-174.9167.7172.7168.30114L959 K961 K972 I975 T976L959-K963 PolarHBondContact O-N 2.63Å; K961-K963 PolarHBondContact O-N 2.97Å; K963-K972 HydrophobicContact CG-CG 4.49Å; K963-K972 VanDerWaalsContact O-CE 3.29Å; K963-K972 WeakPolarHBondContact O-CE 3.37Å; K963-I975 HydrophobicContact CB-CG2 3.99Å; K963-I975 HydrophobicContact CD-CG2 4.5Å; K963-T976 WeakPolarHBondContact CE-OG1 3.37Å; K963-T976 PolarHBondContact NZ-OG1 3.05Å
964G84.9Confident89.6Confident61 Ų6150.4 Ų50.463%0.62928%0.276SS*.THydrogen-bonded Turntrans-87.5-7.317700000115.2K961 L962K961-G964 PolarHBondContact O-N 3.44Å; L962-G964 PolarHBondContact O-N 3.43Å; L962-G964 VanDerWaalsContact O-N 3.14Å
965I87.3Confident89.8Confident21 Ų2149.3 Ų49.311%0.10827%0.27CS..  trans-83.4123.1-173.5-60-174.5000110.5A898 L962 Q967 L968A898-I965 WeakPolarHBondContact O-CD1 3.43Å; L962-I965 HydrophobicContact CD2-CD1 3.82Å; L962-I965 WeakPolarHBondContact O-CB 3.48Å; L962-I965 PolarHBondContact O-N 3.21Å; I965-Q967 VanDerWaalsContact C-N 3.29Å; I965-Q967 HydrophobicContact CG2-CB 4.12Å; I965-Q967 VanDerWaalsContact CG2-OE1 3.23Å; I965-Q967 PolarHBondContact O-N 2.9Å; I965-L968 HydrophobicContact CB-CB 4.49Å; I965-L968 HydrophobicContact CB-CD1 4.22Å; I965-L968 HydrophobicContact CB-CG 4.32Å; I965-L968 HydrophobicContact CD1-CD1 4.42Å; I965-L968 HydrophobicContact CG2-CD1 4.47Å; I965-L968 HydrophobicContact CG2-CG 4.26Å; I965-L968 PolarHBondContact O-N 3.46Å
966P84.2Confident90Very high101 Ų10150.9 Ų50.966%0.65628%0.28SS*.G310 helixtrans-59.4-34.3-178.2-26.335.4000114.5L968 E969P966-L968 PolarHBondContact O-N 2.89Å; P966-E969 PolarHBondContact O-N 3.49Å
967Q83.2Confident90.2Very high118 Ų11851.4 Ų51.455%0.55128%0.28SS*.G310 helixtrans-63.6-17.8176.7-65.786.1-25.100113W906 I965W906-Q967 HydrophobicContact CH2-CB 4.32Å; I965-Q967 VanDerWaalsContact C-N 3.29Å; I965-Q967 HydrophobicContact CG2-CB 4.12Å; I965-Q967 VanDerWaalsContact CG2-OE1 3.23Å; I965-Q967 PolarHBondContact O-N 2.9Å
968L85.4Confident90.4Very high1 Ų148 Ų481%0.00526%0.263CS..G310 helixtrans-10819.5-177.6-58.3179.2000113W906 E908 L911 L962 I965 P966 G970 Q971 K972W906-L968 HydrophobicContact CH2-CD2 4.25Å; W906-L968 HydrophobicContact CZ3-CD2 3.99Å; E908-L968 HydrophobicContact CG-CD2 4.42Å; L911-L968 HydrophobicContact CD1-CD1 3.82Å; L911-L968 HydrophobicContact CD1-CD2 3.59Å; L911-L968 HydrophobicContact CD1-CG 4.36Å; L962-L968 HydrophobicContact CB-CD1 4.14Å; L962-L968 HydrophobicContact CD2-CD1 3.87Å; I965-L968 HydrophobicContact CB-CB 4.49Å; I965-L968 HydrophobicContact CB-CD1 4.22Å; I965-L968 HydrophobicContact CB-CG 4.32Å; I965-L968 HydrophobicContact CD1-CD1 4.42Å; I965-L968 HydrophobicContact CG2-CD1 4.47Å; I965-L968 HydrophobicContact CG2-CG 4.26Å; I965-L968 PolarHBondContact O-N 3.46Å; P966-L968 PolarHBondContact O-N 2.89Å; L968-G970 VanDerWaalsContact C-N 3.26Å; L968-G970 PolarHBondContact O-N 3.32Å; L968-Q971 PolarHBondContact O-N 3.48Å; L968-K972 PolarHBondContact O-N 3.44Å
969E85.6Confident90.6Very high114 Ų11449 Ų4953%0.53327%0.268SS..G310 helixtrans-50.5-45.5178.7-165.368.8-137.600112.2P966 Q971 K972P966-E969 PolarHBondContact O-N 3.49Å; E969-Q971 PolarHBondContact O-N 2.86Å; E969-Q971 VanDerWaalsContact O-N 3.12Å; E969-K972 VanDerWaalsContact CD-CE 3.47Å; E969-K972 PolarHBondContact O-N 2.99Å; E969-K972 WeakPolarHBondContact OE1-CD 3.47Å; E969-K972 WeakPolarHBondContact OE1-CE 3.39Å; E969-K972 IonicContact OE1-NZ 3.62Å; E969-K972 PolarHBondContact OE1-NZ 2.95Å; E969-K972 VanDerWaalsContact OE2-CE 3.23Å; E969-K972 WeakPolarHBondContact OE2-CE 3.35Å; E969-K972 IonicContact OE2-NZ 3.04Å; E969-K972 PolarHBondContact OE2-NZ 2.85Å
970G85Confident90.7Very high54 Ų5454.3 Ų54.356%0.55729%0.293SS*.G310 helixtrans-67.8-6.2179.100000115.5L968L968-G970 VanDerWaalsContact C-N 3.26Å; L968-G970 PolarHBondContact O-N 3.32Å
971Q90.4Very high90.8Very high10 Ų1049.6 Ų49.65%0.04727%0.271CS..G310 helixtrans-112.9-1.7179.8-57.4-57.2-34.500113.3E908 F915 L968 E969 D973 M974 I975E908-Q971 HydrophobicContact CG-CG 4.27Å; E908-Q971 WeakPolarHBondContact OE1-CG 3.35Å; E908-Q971 PolarHBondContact OE1-NE2 2.89Å; F915-Q971 HydrophobicContact CE2-CB 4.11Å; L968-Q971 PolarHBondContact O-N 3.48Å; E969-Q971 PolarHBondContact O-N 2.86Å; E969-Q971 VanDerWaalsContact O-N 3.12Å; Q971-D973 VanDerWaalsContact C-N 3.27Å; Q971-D973 PolarHBondContact O-N 3.44Å; Q971-M974 PolarHBondContact O-N 3.27Å; Q971-M974 VanDerWaalsContact O-N 3.1Å; Q971-I975 HydrophobicContact CB-CD1 4.43Å; Q971-I975 WeakPolarHBondContact O-CG1 3.48Å; Q971-I975 PolarHBondContact O-N 3.47Å
972K91.8Very high91Very high57 Ų5744.5 Ų44.525%0.24825%0.249CC..Hα-helixtrans-57.9-36.7-177.5-76.1-176-179.2172.60113.8K963 L968 E969 T976K963-K972 HydrophobicContact CG-CG 4.49Å; K963-K972 VanDerWaalsContact O-CE 3.29Å; K963-K972 WeakPolarHBondContact O-CE 3.37Å; L968-K972 PolarHBondContact O-N 3.44Å; E969-K972 VanDerWaalsContact CD-CE 3.47Å; E969-K972 PolarHBondContact O-N 2.99Å; E969-K972 WeakPolarHBondContact OE1-CD 3.47Å; E969-K972 WeakPolarHBondContact OE1-CE 3.39Å; E969-K972 IonicContact OE1-NZ 3.62Å; E969-K972 PolarHBondContact OE1-NZ 2.95Å; E969-K972 VanDerWaalsContact OE2-CE 3.23Å; E969-K972 WeakPolarHBondContact OE2-CE 3.35Å; E969-K972 IonicContact OE2-NZ 3.04Å; E969-K972 PolarHBondContact OE2-NZ 2.85Å; K972-T976 VanDerWaalsContact O-CB 3.28Å; K972-T976 WeakPolarHBondContact O-CB 3.44Å; K972-T976 PolarHBondContact O-N 3.02Å; K972-T976 PolarHBondContact O-OG1 3.13Å
973D93.1Very high91.2Very high70 Ų7048.1 Ų48.137%0.37427%0.269SS..Hα-helixtrans-66.6-43.8177.3-74.5-6.4000111D860 E861 A862 Q971 T976 W977D860-D973 WeakPolarHBondContact CA-OD2 3.37Å; D860-D973 HydrophobicContact CB-CB 4.22Å; E861-D973 PolarHBondContact N-OD2 2.93Å; A862-D973 HydrophobicContact CB-CB 4.06Å; Q971-D973 VanDerWaalsContact C-N 3.27Å; Q971-D973 PolarHBondContact O-N 3.44Å; D973-T976 WeakPolarHBondContact O-CB 3.27Å; D973-T976 PolarHBondContact O-N 3.15Å; D973-W977 WeakPolarHBondContact O-CB 3.41Å; D973-W977 PolarHBondContact O-N 3.46Å
974M94.8Very high91.4Very high13 Ų1346 Ų466%0.06426%0.263CS..Hα-helixtrans-65.4-43.9177.4-173.758.3178.500111.9A862 P864 F915 A919 Q971 T976 W977 I978A862-M974 HydrophobicContact CB-CB 4.37Å; A862-M974 HydrophobicContact CB-SD 4.34Å; P864-M974 HydrophobicContact CB-SD 4.47Å; F915-M974 HydrophobicContact CB-CE 4.46Å; F915-M974 HydrophobicContact CB-CG 4.38Å; A919-M974 HydrophobicContact CB-CE 4.16Å; Q971-M974 PolarHBondContact O-N 3.27Å; Q971-M974 VanDerWaalsContact O-N 3.1Å; M974-T976 VanDerWaalsContact C-N 3.29Å; M974-T976 PolarHBondContact O-N 3.21Å; M974-W977 PolarHBondContact O-N 3.38Å; M974-I978 HydrophobicContact CE-CD1 4.19Å; M974-I978 HydrophobicContact CE-CG1 4.4Å; M974-I978 HydrophobicContact CG-CD1 4.41Å; M974-I978 WeakPolarHBondContact O-CG1 3.43Å; M974-I978 PolarHBondContact O-N 3.31Å
975I95.2Very high91.8Very high0 Ų043.1 Ų43.10%023%0.233CC..Hα-helixtrans-60.7-41.4174-62.8165.9000110.5F915 L959 L962 K963 Q971 I978 L979F915-I975 HydrophobicContact CD2-CG1 4.43Å; F915-I975 HydrophobicContact CE1-CG1 4.15Å; F915-I975 HydrophobicContact CE2-CD1 4.09Å; F915-I975 HydrophobicContact CE2-CG1 3.76Å; F915-I975 HydrophobicContact CZ-CD1 3.8Å; F915-I975 HydrophobicContact CZ-CG1 3.61Å; L959-I975 HydrophobicContact CB-CG2 4.18Å; L959-I975 HydrophobicContact CD2-CG2 4.41Å; L959-I975 WeakPolarHBondContact O-CG2 3.32Å; L962-I975 HydrophobicContact CB-CD1 4.25Å; K963-I975 HydrophobicContact CB-CG2 3.99Å; K963-I975 HydrophobicContact CD-CG2 4.5Å; Q971-I975 HydrophobicContact CB-CD1 4.43Å; Q971-I975 WeakPolarHBondContact O-CG1 3.48Å; Q971-I975 PolarHBondContact O-N 3.47Å; I975-I978 PolarHBondContact O-N 2.98Å; I975-L979 HydrophobicContact CG2-CD1 4.12Å; I975-L979 WeakPolarHBondContact O-CG 3.49Å; I975-L979 PolarHBondContact O-N 3.33Å
976T95.1Very high92.1Very high34 Ų3445.6 Ų45.621%0.20924%0.243CC..Hα-helixtrans-65-40.8177.6-58.50000111.9K963 K972 D973 M974 L979 Q980K963-T976 WeakPolarHBondContact CE-OG1 3.37Å; K963-T976 PolarHBondContact NZ-OG1 3.05Å; K972-T976 VanDerWaalsContact O-CB 3.28Å; K972-T976 WeakPolarHBondContact O-CB 3.44Å; K972-T976 PolarHBondContact O-N 3.02Å; K972-T976 PolarHBondContact O-OG1 3.13Å; D973-T976 WeakPolarHBondContact O-CB 3.27Å; D973-T976 PolarHBondContact O-N 3.15Å; M974-T976 VanDerWaalsContact C-N 3.29Å; M974-T976 PolarHBondContact O-N 3.21Å; T976-L979 PolarHBondContact O-N 3.38Å; T976-Q980 VanDerWaalsContact O-CG 3.31Å; T976-Q980 WeakPolarHBondContact O-CG 3.45Å; T976-Q980 PolarHBondContact O-N 2.84Å
977W96.1Very high92.5Very high50 Ų5047.6 Ų47.619%0.18924%0.237CC..Hα-helixtrans-62.4-42.9174.9-175.698.8000111.8A862 P864 A919 L923 D973 M974 Q980 M981A862-W977 HydrophobicContact CB-CB 4.32Å; P864-W977 HydrophobicContact CB-CD2 3.81Å; P864-W977 VanDerWaalsContact CB-CE2 3.5Å; P864-W977 HydrophobicContact CB-CE3 3.97Å; P864-W977 HydrophobicContact CB-CH2 3.59Å; P864-W977 HydrophobicContact CB-CZ2 3.38Å; P864-W977 HydrophobicContact CB-CZ3 3.9Å; P864-W977 HydrophobicContact CG-CD2 4.28Å; P864-W977 HydrophobicContact CG-CZ2 3.89Å; A919-W977 HydrophobicContact CB-CH2 4.29Å; A919-W977 HydrophobicContact CB-CZ3 3.64Å; L923-W977 HydrophobicContact CD1-CH2 4.22Å; L923-W977 HydrophobicContact CD2-CH2 4.18Å; L923-W977 HydrophobicContact CG-CH2 4.16Å; D973-W977 WeakPolarHBondContact O-CB 3.41Å; D973-W977 PolarHBondContact O-N 3.46Å; M974-W977 PolarHBondContact O-N 3.38Å; W977-Q980 PolarHBondContact O-N 2.96Å; W977-M981 HydrophobicContact CH2-CE 3.39Å; W977-M981 HydrophobicContact CH2-CG 4.47Å; W977-M981 HydrophobicContact CZ2-CE 3.27Å; W977-M981 HydrophobicContact CZ3-CB 4.25Å; W977-M981 HydrophobicContact CZ3-CE 4.16Å; W977-M981 PolarHBondContact O-N 2.78Å
978I96.5Very high92.9Very high0 Ų043.9 Ų43.90%022%0.221CC..Hα-helixtrans-62.5-46.1177.2-69.1170.1000110.8F915 L918 L922 L959 M974 I975 Q980 M981 F982F915-I978 HydrophobicContact CB-CD1 3.58Å; F915-I978 HydrophobicContact CD1-CD1 4.12Å; F915-I978 HydrophobicContact CG-CD1 3.99Å; F915-I978 WeakPolarHBondContact O-CD1 3.17Å; L918-I978 HydrophobicContact CD1-CG2 4.43Å; L922-I978 HydrophobicContact CD1-CG2 4.05Å; L959-I978 HydrophobicContact CD1-CG2 3.61Å; M974-I978 HydrophobicContact CE-CD1 4.19Å; M974-I978 HydrophobicContact CE-CG1 4.4Å; M974-I978 HydrophobicContact CG-CD1 4.41Å; M974-I978 WeakPolarHBondContact O-CG1 3.43Å; M974-I978 PolarHBondContact O-N 3.31Å; I975-I978 PolarHBondContact O-N 2.98Å; I978-Q980 VanDerWaalsContact C-N 3.33Å; I978-Q980 PolarHBondContact O-N 2.66Å; I978-M981 CarbonylContact O-C 3.6Å; I978-M981 WeakPolarHBondContact O-CA 3.43Å; I978-M981 WeakPolarHBondContact O-CB 3.17Å; I978-M981 PolarHBondContact O-N 2.93Å; I978-F982 HydrophobicContact CG2-CD2 3.83Å; I978-F982 HydrophobicContact CG2-CE2 3.71Å; I978-F982 WeakPolarHBondContact O-CD2 3.35Å; I978-F982 PolarHBondContact O-N 2.94Å
979L95.7Very high93Very high23 Ų2344.7 Ų44.712%0.1222%0.224CC..Hα-helixtrans-60.1-41.7176.7-69169.7000111.8Q956 L959 E960 I975 T976 M981 F982 D983Q956-L979 HydrophobicContact CG-CD2 3.8Å; L959-L979 HydrophobicContact CB-CD2 4.04Å; L959-L979 HydrophobicContact CB-CG 4.48Å; L959-L979 HydrophobicContact CD1-CD2 4.28Å; E960-L979 HydrophobicContact CG-CD1 4.33Å; E960-L979 HydrophobicContact CG-CD2 4.32Å; I975-L979 HydrophobicContact CG2-CD1 4.12Å; I975-L979 WeakPolarHBondContact O-CG 3.49Å; I975-L979 PolarHBondContact O-N 3.33Å; T976-L979 PolarHBondContact O-N 3.38Å; L979-M981 VanDerWaalsContact C-N 3.27Å; L979-M981 PolarHBondContact O-N 3.24Å; L979-F982 WeakPolarHBondContact O-CB 3.28Å; L979-F982 PolarHBondContact O-N 3.1Å; L979-D983 PolarHBondContact O-N 2.68Å; L979-D983 VanDerWaalsContact O-N 3.08Å
980Q95.7Very high92.9Very high113 Ų11344.2 Ų44.253%0.52822%0.222SC..Hα-helixtrans-64.3-30172.9-70.8173.17.800113T976 W977 I978 T984T976-Q980 VanDerWaalsContact O-CG 3.31Å; T976-Q980 WeakPolarHBondContact O-CG 3.45Å; T976-Q980 PolarHBondContact O-N 2.84Å; W977-Q980 PolarHBondContact O-N 2.96Å; I978-Q980 VanDerWaalsContact C-N 3.33Å; I978-Q980 PolarHBondContact O-N 2.66Å; Q980-T984 WeakPolarHBondContact O-CB 3.35Å; Q980-T984 PolarHBondContact O-N 3.43Å; Q980-T984 PolarHBondContact O-OG1 3.31Å
981M95.6Very high92.1Very high13 Ų1348.6 Ų48.66%0.06423%0.225CC..Hα-helixtrans-74.3-39.5175-164.163.370.900111.7L922 L923 K926 W977 I978 L979 D983 T984 V985L922-M981 HydrophobicContact CB-CB 4.43Å; L922-M981 HydrophobicContact CB-CG 3.65Å; L922-M981 HydrophobicContact CD1-CB 4.06Å; L922-M981 HydrophobicContact CD1-CG 4.2Å; L923-M981 HydrophobicContact CD2-CE 3.85Å; K926-M981 HydrophobicContact CD-CE 4.46Å; K926-M981 HydrophobicContact CD-SD 3.6Å; K926-M981 VanDerWaalsContact CD-SD 3.6Å; W977-M981 HydrophobicContact CH2-CE 3.39Å; W977-M981 HydrophobicContact CH2-CG 4.47Å; W977-M981 HydrophobicContact CZ2-CE 3.27Å; W977-M981 HydrophobicContact CZ3-CB 4.25Å; W977-M981 HydrophobicContact CZ3-CE 4.16Å; W977-M981 PolarHBondContact O-N 2.78Å; I978-M981 CarbonylContact O-C 3.6Å; I978-M981 WeakPolarHBondContact O-CA 3.43Å; I978-M981 WeakPolarHBondContact O-CB 3.17Å; I978-M981 PolarHBondContact O-N 2.93Å; L979-M981 VanDerWaalsContact C-N 3.27Å; L979-M981 PolarHBondContact O-N 3.24Å; M981-D983 VanDerWaalsContact C-N 3.34Å; M981-D983 PolarHBondContact O-N 3.14Å; M981-T984 WeakPolarHBondContact O-CA 3.5Å; M981-T984 WeakPolarHBondContact O-CB 3.34Å; M981-T984 PolarHBondContact O-N 3.3Å; M981-T984 HydrophobicContact SD-CG2 4.39Å; M981-V985 PolarHBondContact O-N 3.44Å
982F95.8Very high90.3Very high1 Ų149.8 Ų49.80%0.00424%0.235CC..Hα-helixtrans-53.3-50.4168.4-88.5-81.2000111L922 Y942 A945 I955 L959 I978 L979 T984 V985 K986L922-F982 HydrophobicContact CD1-CD2 3.62Å; L922-F982 HydrophobicContact CD1-CE2 3.68Å; L922-F982 HydrophobicContact CD1-CG 4.08Å; L922-F982 HydrophobicContact CD1-CZ 4.18Å; L922-F982 HydrophobicContact CD2-CD1 3.94Å; L922-F982 HydrophobicContact CD2-CD2 4.43Å; L922-F982 HydrophobicContact CD2-CE1 3.98Å; L922-F982 HydrophobicContact CD2-CE2 4.48Å; L922-F982 HydrophobicContact CD2-CG 4.15Å; L922-F982 HydrophobicContact CD2-CZ 4.25Å; Y942-F982 AromaticContact CD2-CD1 3.71Å; Y942-F982 HydrophobicContact CD2-CD1 3.71Å; Y942-F982 HydrophobicContact CD2-CE1 4.32Å; Y942-F982 AromaticContact CE2-CD1 3.94Å; Y942-F982 HydrophobicContact CE2-CD1 3.94Å; A945-F982 HydrophobicContact CB-CE1 3.81Å; A945-F982 HydrophobicContact CB-CZ 3.91Å; I955-F982 HydrophobicContact CG2-CZ 4.39Å; L959-F982 HydrophobicContact CD1-CD2 4.39Å; L959-F982 HydrophobicContact CD1-CE2 3.82Å; I978-F982 HydrophobicContact CG2-CD2 3.83Å; I978-F982 HydrophobicContact CG2-CE2 3.71Å; I978-F982 WeakPolarHBondContact O-CD2 3.35Å; I978-F982 PolarHBondContact O-N 2.94Å; L979-F982 WeakPolarHBondContact O-CB 3.28Å; L979-F982 PolarHBondContact O-N 3.1Å; F982-T984 PolarHBondContact O-N 3.44Å; F982-V985 PolarHBondContact O-N 3.24Å; F982-K986 WeakPolarHBondContact O-CB 3.42Å; F982-K986 PolarHBondContact O-N 3.19Å
983D94.1Very high87.9Confident75 Ų7551.4 Ų51.440%0.40125%0.252SS..Hα-helixtrans-62.7-26.1175.8-75.5-27.3000113.4L979 M981 R987L979-D983 PolarHBondContact O-N 2.68Å; L979-D983 VanDerWaalsContact O-N 3.08Å; M981-D983 VanDerWaalsContact C-N 3.34Å; M981-D983 PolarHBondContact O-N 3.14Å; D983-R987 WeakPolarHBondContact O-CB 3.49Å; D983-R987 VanDerWaalsContact O-CG 3.23Å; D983-R987 WeakPolarHBondContact O-CG 3.18Å; D983-R987 PolarHBondContact O-N 3.04Å; D983-R987 PolarHBondContact O-NE 2.92Å
984T94.9Very high85.3Confident38 Ų3855 Ų5523%0.23327%0.271CS..Hα-helixtrans-78.9-45.4178.3-620000111.6K926 Q980 M981 F982 R987 L988K926-T984 HydrophobicContact CD-CG2 4.38Å; Q980-T984 WeakPolarHBondContact O-CB 3.35Å; Q980-T984 PolarHBondContact O-N 3.43Å; Q980-T984 PolarHBondContact O-OG1 3.31Å; M981-T984 WeakPolarHBondContact O-CA 3.5Å; M981-T984 WeakPolarHBondContact O-CB 3.34Å; M981-T984 PolarHBondContact O-N 3.3Å; M981-T984 HydrophobicContact SD-CG2 4.39Å; F982-T984 PolarHBondContact O-N 3.44Å; T984-R987 PolarHBondContact O-N 3Å; T984-R987 PolarHBondContact OG1-NH2 3.11Å; T984-R987 VanDerWaalsContact OG1-NH2 3.14Å; T984-L988 WeakPolarHBondContact O-CG 3.33Å; T984-L988 PolarHBondContact O-N 3.39Å; T984-L988 VanDerWaalsContact O-N 3.16Å
985V93.6Very high82.8Confident0 Ų061.3 Ų61.30%030%0.303CS..Hα-helixtrans-64.7-44.5174.5177.40000110.6L922 E925 K926 L929 Y942 M981 F982 R987 L988 R989L922-V985 HydrophobicContact CB-CG2 4.29Å; L922-V985 HydrophobicContact CD2-CG2 4.18Å; L922-V985 WeakPolarHBondContact O-CG2 3.4Å; E925-V985 HydrophobicContact CB-CG1 4.34Å; E925-V985 HydrophobicContact CG-CG1 3.88Å; K926-V985 HydrophobicContact CB-CG2 4.03Å; L929-V985 HydrophobicContact CD1-CG1 4.08Å; Y942-V985 HydrophobicContact CD2-CG1 4.44Å; Y942-V985 HydrophobicContact CG-CG1 4.13Å; M981-V985 PolarHBondContact O-N 3.44Å; F982-V985 PolarHBondContact O-N 3.24Å; V985-R987 VanDerWaalsContact C-N 3.34Å; V985-R987 PolarHBondContact O-N 2.7Å; V985-L988 WeakPolarHBondContact O-CA 3.49Å; V985-L988 WeakPolarHBondContact O-CB 3.38Å; V985-L988 PolarHBondContact O-N 3.38Å; V985-R989 PolarHBondContact O-N 3.43Å
986K92.7Very high79.9Confident72 Ų7267 Ų6731%0.31334%0.338SS..Hα-helixtrans-50.9-51173.3-179.5-179.6177.6177.60112.1Y942 F982 L988 R989 E990Y942-K986 HydrophobicContact CE1-CB 4.44Å; Y942-K986 HydrophobicContact CE2-CB 3.82Å; Y942-K986 HydrophobicContact CE2-CG 4.47Å; Y942-K986 WeakPolarHBondContact OH-CD 3.5Å; Y942-K986 WeakPolarHBondContact OH-CG 3.41Å; F982-K986 WeakPolarHBondContact O-CB 3.42Å; F982-K986 PolarHBondContact O-N 3.19Å; K986-L988 VanDerWaalsContact C-N 3.25Å; K986-L988 PolarHBondContact O-N 3.22Å; K986-R989 PolarHBondContact O-N 3.19Å; K986-E990 VanDerWaalsContact CE-CD 3.44Å; K986-E990 WeakPolarHBondContact CE-OE1 3.39Å; K986-E990 WeakPolarHBondContact CE-OE2 3.34Å; K986-E990 HydrophobicContact CG-CG 4.33Å; K986-E990 IonicContact NZ-OE1 2.63Å; K986-E990 WeakPolarHBondContact O-CB 3.2Å; K986-E990 WeakPolarHBondContact O-CG 3.49Å; K986-E990 PolarHBondContact O-N 3.33Å
987R92.6Very high77.1Confident144 Ų14469.2 Ų69.254%0.54336%0.359SS..Hα-helixtrans-67.7-19.8178.3-75.1178.2-62.9167.92.9114.2D983 T984 V985 K991D983-R987 WeakPolarHBondContact O-CB 3.49Å; D983-R987 VanDerWaalsContact O-CG 3.23Å; D983-R987 WeakPolarHBondContact O-CG 3.18Å; D983-R987 PolarHBondContact O-N 3.04Å; D983-R987 PolarHBondContact O-NE 2.92Å; T984-R987 PolarHBondContact O-N 3Å; T984-R987 PolarHBondContact OG1-NH2 3.11Å; T984-R987 VanDerWaalsContact OG1-NH2 3.14Å; V985-R987 VanDerWaalsContact C-N 3.34Å; V985-R987 PolarHBondContact O-N 2.7Å; R987-K991 VanDerWaalsContact O-CB 3.31Å; R987-K991 WeakPolarHBondContact O-CB 3.42Å; R987-K991 WeakPolarHBondContact O-CD 3.39Å; R987-K991 WeakPolarHBondContact O-CG 3.25Å; R987-K991 PolarHBondContact O-N 2.55Å
988L90.9Very high74.1Confident39 Ų3973.1 Ų73.120%0.20439%0.389CS..Hα-helixtrans-79.4-43.5173.4-72.2169.2000110.9K926 L929 Q930 T984 V985 K986K926-L988 HydrophobicContact CB-CD1 4.47Å; K926-L988 HydrophobicContact CG-CD1 3.92Å; L929-L988 HydrophobicContact CB-CB 4.11Å; L929-L988 HydrophobicContact CB-CD1 4.38Å; L929-L988 HydrophobicContact CD1-CB 3.91Å; Q930-L988 HydrophobicContact CG-CD1 4.23Å; T984-L988 WeakPolarHBondContact O-CG 3.33Å; T984-L988 PolarHBondContact O-N 3.39Å; T984-L988 VanDerWaalsContact O-N 3.16Å; V985-L988 WeakPolarHBondContact O-CA 3.49Å; V985-L988 WeakPolarHBondContact O-CB 3.38Å; V985-L988 PolarHBondContact O-N 3.38Å; K986-L988 VanDerWaalsContact C-N 3.25Å; K986-L988 PolarHBondContact O-N 3.22Å
989R87.3Confident70.9Confident19 Ų1979.6 Ų79.67%0.07243%0.428CS..Hα-helixtrans-58.6-54.7169.3-69.7-72-175.8-173.9-0.6111.4E925 L929 E934 V937 F939 V985 K986 K991 S992E925-R989 IonicContact OE1-CZ 2.74Å; E925-R989 VanDerWaalsContact OE1-CZ 3.25Å; E925-R989 IonicContact OE1-NE 3.79Å; E925-R989 PolarHBondContact OE1-NE 2.56Å; E925-R989 IonicContact OE1-NH2 3.72Å; E925-R989 PolarHBondContact OE1-NH2 3.33Å; L929-R989 HydrophobicContact CD1-CG 3.89Å; E934-R989 VanDerWaalsContact CD-O 3.27Å; E934-R989 PolarHBondContact O-NH1 2.84Å; E934-R989 WeakPolarHBondContact OE1-CD 3.14Å; V937-R989 PolarHBondContact O-NH1 3.28Å; V937-R989 PolarHBondContact O-NH2 3.11Å; V937-R989 VanDerWaalsContact O-NH2 3.08Å; F939-R989 PolarHBondContact O-NH2 3.34Å; V985-R989 PolarHBondContact O-N 3.43Å; K986-R989 PolarHBondContact O-N 3.19Å; R989-K991 PolarHBondContact O-N 3.07Å; R989-K991 VanDerWaalsContact O-N 3.08Å; R989-S992 PolarHBondContact O-N 2.66Å
990E84.1Confident67.8Low103 Ų10384.2 Ų84.248%0.48146%0.463SS..Hα-helixtrans-65-18.6-175.4-70.3175.7162.300114.5K986K986-E990 VanDerWaalsContact CE-CD 3.44Å; K986-E990 WeakPolarHBondContact CE-OE1 3.39Å; K986-E990 WeakPolarHBondContact CE-OE2 3.34Å; K986-E990 HydrophobicContact CG-CG 4.33Å; K986-E990 IonicContact NZ-OE1 2.63Å; K986-E990 WeakPolarHBondContact O-CB 3.2Å; K986-E990 WeakPolarHBondContact O-CG 3.49Å; K986-E990 PolarHBondContact O-N 3.33Å
991K68.1Low64.6Low147 Ų14782.7 Ų82.764%0.63948%0.478SS*.Hα-helixtrans-71.4-28.7-176.3-103.1178.6176.2-173.70114.5R987 R989R987-K991 VanDerWaalsContact O-CB 3.31Å; R987-K991 WeakPolarHBondContact O-CB 3.42Å; R987-K991 WeakPolarHBondContact O-CD 3.39Å; R987-K991 WeakPolarHBondContact O-CG 3.25Å; R987-K991 PolarHBondContact O-N 2.55Å; R989-K991 PolarHBondContact O-N 3.07Å; R989-K991 VanDerWaalsContact O-N 3.08Å
992S52.1Low61.3Low35 Ų3587.5 Ų87.525%0.24551%0.512CS..Hα-helixtrans-84.2-29.4-176.8-61.80000112.4E934 R989 L994 I995E934-S992 WeakPolarHBondContact OE2-CB 3.26Å; R989-S992 PolarHBondContact O-N 2.66Å; S992-L994 PolarHBondContact O-N 2.67Å; S992-I995 PolarHBondContact O-N 3.35Å
993C41.3Very low58Low91 Ų9195.6 Ų95.662%0.61555%0.55SS**THydrogen-bonded Turntrans-56.5-15.3176.1-78.40000115.2
994L39.7Very low54.8Low146 Ų14696.4 Ų96.476%0.76456%0.562SS**THydrogen-bonded Turntrans-86.6-7.4-178.8-73.8168.5000115S992S992-L994 PolarHBondContact O-N 2.67Å
995I41Very low51.7Low145 Ų145101.5 Ų101.574%0.74459%0.586SS**SBendtrans-95.8-21.1-172.5-63.2177.1000113.1S992S992-I995 PolarHBondContact O-N 3.35Å
996V36.1Very low48.7Very low119 Ų119109.9 Ų109.972%0.72162%0.623SS**SBendtrans-86.5-11.7-172.9-175.60000113.5
997A35.3Very low45.6Very low80 Ų80113.2 Ų113.266%0.66164%0.644SS**SBendtrans-107.759.3-172.700000114.3
998T32.3Very low42.7Very low133 Ų133113.7 Ų113.782%0.81666%0.657SS**  trans-168.881.6153.810.80000113.1
999T31.3Very low40Very low135 Ų135120.4 Ų120.483%0.82869%0.688SS**  trans-116.780.7163.544.50000110.9
1000S30.2Very low37.6Very low121 Ų121127.5 Ų127.585%0.84673%0.725SS**  trans-168127.4160.72.30000112.7
1001G28.6Very low35.4Very low81 Ų81128.6 Ų128.684%0.83574%0.739SS**  trans90.8118.515300000118.3
1002S26.1Very low34.2Very low113 Ų113128.9 Ų128.979%0.7974%0.742SS**  trans-66.1168.8155.951.50000110.9
1003E26.5Very low34Very low171 Ų171133.7 Ų133.780%0.79977%0.765SS**  cis-150.6129.835.2-66.4177.1144.700109.7
1004S27Very low34.1Very low93 Ų93138 Ų13865%0.6577%0.773SS**  87.8129.293.495.80000117.5
1005I30.2Very low34.6Very low144 Ų144136.8 Ų136.874%0.73876%0.764SS**  trans71125.4139.6-67.8169.2000116.6
1006K30.3Very low35.2Very low177 Ų177137.2 Ų137.277%0.7776%0.76SS**  cis-169173.914.4-130.5176.3-160.61740113.7
1007N26.2Very low36.3Very low142 Ų142134.7 Ų134.776%0.75975%0.752SS**  trans93.5111.5151.5-71.26.9000120.4
1008D31.9Very low37.2Very low153 Ų153135.9 Ų135.982%0.81874%0.744SS**  trans-75.5-176.2164.3-67.1-72000113.9
1009E34.2Very low38.5Very low181 Ų181138.6 Ų138.685%0.84674%0.739SS**  trans73.597162.9-59.6-174.2165.100117.4
1010I36.3Very low40.1Very low167 Ų167139.8 Ų139.886%0.85673%0.733SS**SBend175.273.1122.1-79.4148.8000108.8
1011T39.4Very low41.7Very low126 Ų126143.9 Ų143.977%0.77373%0.73SS**SBendtrans-148.2-16168.636.80000114.6D1013T1011-D1013 VanDerWaalsContact C-N 3.34Å; T1011-D1013 PolarHBondContact O-N 2.69Å
1012H41.6Very low43.3Very low154 Ų154146.3 Ų146.371%0.71372%0.717SS**Hα-helixtrans-75.6-11.6-165.8-145.5-52.1000115.9
1013D47.8Very low45.2Very low136 Ų136143.9 Ų143.973%0.72770%0.704SS**Hα-helixtrans-89.7-19.1-179.5-92.7-29.2000115.1T1011T1011-D1013 VanDerWaalsContact C-N 3.34Å; T1011-D1013 PolarHBondContact O-N 2.69Å
1014K44.1Very low47.1Very low181 Ų181141.5 Ų141.579%0.78769%0.693SS**Hα-helixtrans-75.4-42.6179.6-82-177.2175.5175.10112.8K1016 A1017 E1018K1014-K1016 VanDerWaalsContact C-N 3.33Å; K1014-K1016 PolarHBondContact O-N 2.95Å; K1014-A1017 PolarHBondContact O-N 3.49Å; K1014-E1018 PolarHBondContact O-N 2.89Å
1015E50.5Low48.8Very low120 Ų120139.8 Ų139.856%0.56168%0.684SS**Hα-helixtrans-67.1-32.5179.1-72.4-162114.400113.3E1018 R1019E1015-E1018 PolarHBondContact O-N 2.89Å; E1015-R1019 WeakPolarHBondContact O-CB 3.32Å; E1015-R1019 PolarHBondContact O-N 3.37Å
1016K54.5Low50.3Low155 Ų155134.7 Ų134.767%0.67466%0.663SS**Hα-helixtrans-68.9-36.2-179-160.1172.3-175.6176.80111.9K1014 K1020K1014-K1016 VanDerWaalsContact C-N 3.33Å; K1014-K1016 PolarHBondContact O-N 2.95Å; K1016-K1020 PolarHBondContact O-N 3.31Å
1017A57.8Low52.1Low65 Ų65134.4 Ų134.454%0.53766%0.658SS.*Hα-helixtrans-69.8-39.8173.100000112.4K1014 K1020 R1021K1014-A1017 PolarHBondContact O-N 3.49Å; A1017-K1020 PolarHBondContact O-N 2.94Å; A1017-R1021 PolarHBondContact O-N 3.36Å
1018E53.8Low54Low106 Ų106132.9 Ų132.950%0.49565%0.649SS.*Hα-helixtrans-71.5-42-178.9-158.9-174.2137.500112.7K1014 E1015 K1020 R1021 K1022K1014-E1018 PolarHBondContact O-N 2.89Å; E1015-E1018 PolarHBondContact O-N 2.89Å; E1018-K1020 VanDerWaalsContact C-N 3.28Å; E1018-K1020 PolarHBondContact O-N 3.35Å; E1018-R1021 PolarHBondContact O-N 2.94Å; E1018-K1022 PolarHBondContact O-N 2.93Å; E1018-K1022 WeakPolarHBondContact OE1-CE 3.22Å; E1018-K1022 IonicContact OE1-NZ 2.79Å; E1018-K1022 PolarHBondContact OE1-NZ 3.02Å
1019R59.4Low55.4Low189 Ų189131.2 Ų131.271%0.71364%0.636SS**Hα-helixtrans-59.5-37.4173.5-81.4-177.3171174.8-0.4112.1E1015 A1023E1015-R1019 WeakPolarHBondContact O-CB 3.32Å; E1015-R1019 PolarHBondContact O-N 3.37Å; R1019-A1023 WeakPolarHBondContact O-CB 3.5Å; R1019-A1023 PolarHBondContact O-N 3.45Å
1020K66Low56.5Low161 Ų161130.3 Ų130.370%0.763%0.625SS**Hα-helixtrans-67.4-42.9178.1-156174.8-175.9-176.60112.1K1016 A1017 E1018 A1023 E1024K1016-K1020 PolarHBondContact O-N 3.31Å; A1017-K1020 PolarHBondContact O-N 2.94Å; E1018-K1020 VanDerWaalsContact C-N 3.28Å; E1018-K1020 PolarHBondContact O-N 3.35Å; K1020-A1023 PolarHBondContact O-N 2.88Å; K1020-E1024 WeakPolarHBondContact O-CB 3.48Å; K1020-E1024 PolarHBondContact O-N 3.08Å
1021R64.6Low58Low206 Ų206127.6 Ų127.678%0.77761%0.609SS**Hα-helixtrans-63-43.2173.8-101.4-177.5170.3-179.3-2.5113.1A1017 E1018 E1024 A1025A1017-R1021 PolarHBondContact O-N 3.36Å; E1018-R1021 PolarHBondContact O-N 2.94Å; R1021-E1024 PolarHBondContact O-N 3.09Å; R1021-A1025 WeakPolarHBondContact O-CB 3.26Å; R1021-A1025 PolarHBondContact O-N 3.24Å
1022K61.4Low59.2Low133 Ų133128.7 Ų128.758%0.57860%0.603SS**Hα-helixtrans-66.1-38.1177.1-80.8172170.5164.90112.3E1018 A1026E1018-K1022 PolarHBondContact O-N 2.93Å; E1018-K1022 WeakPolarHBondContact OE1-CE 3.22Å; E1018-K1022 IonicContact OE1-NZ 2.79Å; E1018-K1022 PolarHBondContact OE1-NZ 3.02Å; K1022-A1026 WeakPolarHBondContact O-CB 3.39Å; K1022-A1026 PolarHBondContact O-N 2.91Å
1023A66.1Low60.1Low62 Ų62124.9 Ų124.951%0.51259%0.587SS.*Hα-helixtrans-65.7-41.5175.300000112.8R1019 K1020 A1026 R1027R1019-A1023 WeakPolarHBondContact O-CB 3.5Å; R1019-A1023 PolarHBondContact O-N 3.45Å; K1020-A1023 PolarHBondContact O-N 2.88Å; A1023-A1026 PolarHBondContact O-N 3.23Å; A1023-R1027 PolarHBondContact O-N 2.92Å
1024E66.3Low60.6Low121 Ų121124.7 Ų124.757%0.56558%0.583SS**Hα-helixtrans-69.4-40.4179.2-167.8161.9-143.900112.1K1020 R1021 A1026 R1027 L1028K1020-E1024 WeakPolarHBondContact O-CB 3.48Å; K1020-E1024 PolarHBondContact O-N 3.08Å; R1021-E1024 PolarHBondContact O-N 3.09Å; E1024-A1026 PolarHBondContact O-N 2.79Å; E1024-R1027 PolarHBondContact O-N 2.73Å; E1024-R1027 VanDerWaalsContact O-N 3.14Å; E1024-L1028 PolarHBondContact O-N 3.33Å
1025A63.2Low61.6Low57 Ų57119 Ų11947%0.47157%0.57SS.*Hα-helixtrans-60.6-41.8170.600000112.3R1021 R1027 L1028 H1029R1021-A1025 WeakPolarHBondContact O-CB 3.26Å; R1021-A1025 PolarHBondContact O-N 3.24Å; A1025-R1027 VanDerWaalsContact C-N 3.27Å; A1025-R1027 PolarHBondContact O-N 2.96Å; A1025-L1028 PolarHBondContact O-N 2.93Å; A1025-H1029 WeakPolarHBondContact O-CB 3.34Å; A1025-H1029 PolarHBondContact O-N 3.41Å
1026A60.6Low61.8Low36 Ų36118.9 Ų118.930%0.29857%0.569SS.*Hα-helixtrans-70.1-20175.600000113.7K1022 A1023 E1024 R1030K1022-A1026 WeakPolarHBondContact O-CB 3.39Å; K1022-A1026 PolarHBondContact O-N 2.91Å; A1023-A1026 PolarHBondContact O-N 3.23Å; E1024-A1026 PolarHBondContact O-N 2.79Å; A1026-R1030 PolarHBondContact O-N 3.22Å; A1026-R1030 PolarHBondContact O-NE 3.05Å
1027R68.1Low61.6Low171 Ų171117.5 Ų117.565%0.64557%0.566SS**Hα-helixtrans-78.9-48.5170.1-161.2-17987.1148.63110.9A1023 E1024 A1025 H1029 R1030 Q1031A1023-R1027 PolarHBondContact O-N 2.92Å; E1024-R1027 PolarHBondContact O-N 2.73Å; E1024-R1027 VanDerWaalsContact O-N 3.14Å; A1025-R1027 VanDerWaalsContact C-N 3.27Å; A1025-R1027 PolarHBondContact O-N 2.96Å; R1027-H1029 VanDerWaalsContact C-N 3.31Å; R1027-H1029 PolarHBondContact O-N 2.87Å; R1027-R1030 PolarHBondContact O-N 3.32Å; R1027-Q1031 WeakPolarHBondContact O-CB 3.46Å; R1027-Q1031 PolarHBondContact O-N 3.21Å
1028L66.7Low61.8Low111 Ų111117.5 Ų117.558%0.58156%0.563SS**Hα-helixtrans-58.7-39.9175.7-90.8154.2000112.3E1024 A1025 Q1031 K1032E1024-L1028 PolarHBondContact O-N 3.33Å; A1025-L1028 PolarHBondContact O-N 2.93Å; L1028-Q1031 PolarHBondContact O-N 3.45Å; L1028-K1032 WeakPolarHBondContact O-CB 3.41Å; L1028-K1032 PolarHBondContact O-N 3Å
1029H60.3Low62.3Low118 Ų118114.7 Ų114.755%0.54656%0.558SS.*Hα-helixtrans-63.6-47.2175.2-172.166.6000112.2A1025 R1027 Q1031 K1032 I1033A1025-H1029 WeakPolarHBondContact O-CB 3.34Å; A1025-H1029 PolarHBondContact O-N 3.41Å; R1027-H1029 VanDerWaalsContact C-N 3.31Å; R1027-H1029 PolarHBondContact O-N 2.87Å; H1029-Q1031 VanDerWaalsContact C-N 3.34Å; H1029-Q1031 PolarHBondContact O-N 2.89Å; H1029-K1032 PolarHBondContact O-N 3.22Å; H1029-I1033 PolarHBondContact O-N 2.65Å
1030R57.7Low62.2Low161 Ų161111.3 Ų111.361%0.60855%0.553SS**Hα-helixtrans-64-36.3175.7-81.2-179.4-86.9-152-1.5113.1A1026 R1027 K1032 I1033 M1034A1026-R1030 PolarHBondContact O-N 3.22Å; A1026-R1030 PolarHBondContact O-NE 3.05Å; R1027-R1030 PolarHBondContact O-N 3.32Å; R1030-K1032 VanDerWaalsContact C-N 3.34Å; R1030-I1033 PolarHBondContact O-N 3.27Å; R1030-M1034 PolarHBondContact O-N 3Å
1031Q68.1Low61.4Low111 Ų111109.8 Ų109.852%0.51955%0.549SS..Hα-helixtrans-68.6-34.5175.6-152.8168.716.300111.7R1027 L1028 H1029 A1035R1027-Q1031 WeakPolarHBondContact O-CB 3.46Å; R1027-Q1031 PolarHBondContact O-N 3.21Å; L1028-Q1031 PolarHBondContact O-N 3.45Å; H1029-Q1031 VanDerWaalsContact C-N 3.34Å; H1029-Q1031 PolarHBondContact O-N 2.89Å; Q1031-A1035 WeakPolarHBondContact O-CB 3.49Å; Q1031-A1035 PolarHBondContact O-N 3.31Å
1032K65.4Low61.1Low149 Ų149107 Ų10765%0.64854%0.542SS*.Hα-helixtrans-70.3-38.2174.6-154.8173.2-173-179.10112.5L1028 H1029 R1030 A1035 Q1036L1028-K1032 WeakPolarHBondContact O-CB 3.41Å; L1028-K1032 PolarHBondContact O-N 3Å; H1029-K1032 PolarHBondContact O-N 3.22Å; R1030-K1032 VanDerWaalsContact C-N 3.34Å; K1032-A1035 PolarHBondContact O-N 3.27Å; K1032-Q1036 PolarHBondContact O-N 3.3Å
1033I59.3Low61Low73 Ų73105.4 Ų105.437%0.37454%0.54SS..Hα-helixtrans-69-41.3173.1-68.3-172.8000111.5H1029 R1030 A1035 Q1036 M1037H1029-I1033 PolarHBondContact O-N 2.65Å; R1030-I1033 PolarHBondContact O-N 3.27Å; I1033-A1035 VanDerWaalsContact C-N 3.32Å; I1033-A1035 PolarHBondContact O-N 2.94Å; I1033-Q1036 PolarHBondContact O-N 3.3Å; I1033-M1037 HydrophobicContact CG2-CG 4.43Å; I1033-M1037 WeakPolarHBondContact O-CG 3.32Å; I1033-M1037 PolarHBondContact O-N 2.95Å
1034M57.8Low60.2Low133 Ų133108.3 Ų108.366%0.65554%0.541SS*.Hα-helixtrans-62.1-38.6172.5-80.4-168.9-116.100112.5R1030 M1037 S1038R1030-M1034 PolarHBondContact O-N 3Å; M1034-M1037 PolarHBondContact O-N 3.41Å; M1034-S1038 WeakPolarHBondContact O-CB 3.36Å; M1034-S1038 PolarHBondContact O-N 3.12Å
1035A66.8Low59.8Low61 Ų61107.4 Ų107.450%0.50454%0.539SS..Hα-helixtrans-64.9-38173.900000112.4Q1031 K1032 I1033 A1039Q1031-A1035 WeakPolarHBondContact O-CB 3.49Å; Q1031-A1035 PolarHBondContact O-N 3.31Å; K1032-A1035 PolarHBondContact O-N 3.27Å; I1033-A1035 VanDerWaalsContact C-N 3.32Å; I1033-A1035 PolarHBondContact O-N 2.94Å; A1035-A1039 VanDerWaalsContact O-CB 3.26Å; A1035-A1039 WeakPolarHBondContact O-CB 3.37Å; A1035-A1039 PolarHBondContact O-N 3.24Å
1036Q54.3Low59.5Low118 Ų118110.4 Ų110.455%0.55154%0.543SS*.Hα-helixtrans-67.7-43.6173.2-77.8-178.2-65.300112.5K1032 I1033 S1038 A1039 L1040K1032-Q1036 PolarHBondContact O-N 3.3Å; I1033-Q1036 PolarHBondContact O-N 3.3Å; Q1036-S1038 PolarHBondContact O-N 3.19Å; Q1036-A1039 PolarHBondContact O-N 3.16Å; Q1036-L1040 WeakPolarHBondContact O-CB 3.48Å; Q1036-L1040 WeakPolarHBondContact O-CG 3.21Å; Q1036-L1040 PolarHBondContact O-N 3.14Å
1037M49.8Very low59.3Low125 Ų125113.5 Ų113.562%0.61656%0.559SS**Hα-helixtrans-58.2-47.4173.7-74.6-74.1-159.500111I1033 M1034 A1039 L1040 Q1041I1033-M1037 HydrophobicContact CG2-CG 4.43Å; I1033-M1037 WeakPolarHBondContact O-CG 3.32Å; I1033-M1037 PolarHBondContact O-N 2.95Å; M1034-M1037 PolarHBondContact O-N 3.41Å; M1037-A1039 PolarHBondContact O-N 3.27Å; M1037-L1040 PolarHBondContact O-N 3.07Å; M1037-Q1041 VanDerWaalsContact O-CB 3.32Å; M1037-Q1041 WeakPolarHBondContact O-CB 3.43Å; M1037-Q1041 PolarHBondContact O-N 3.32Å
1038S61.5Low58.7Low65 Ų65109.6 Ų109.646%0.45555%0.547SS..Hα-helixtrans-65.7-36.8178.3-174.50000112.8M1034 Q1036 Q1041 K1042M1034-S1038 WeakPolarHBondContact O-CB 3.36Å; M1034-S1038 PolarHBondContact O-N 3.12Å; Q1036-S1038 PolarHBondContact O-N 3.19Å; S1038-Q1041 PolarHBondContact O-N 3.01Å; S1038-K1042 WeakPolarHBondContact O-CB 3.44Å; S1038-K1042 PolarHBondContact O-N 3.3Å
1039A64.7Low57.7Low48 Ų48110 Ų11040%0.39754%0.544SS..Hα-helixtrans-70.8-34.6175.100000113.1A1035 Q1036 M1037 N1043A1035-A1039 VanDerWaalsContact O-CB 3.26Å; A1035-A1039 WeakPolarHBondContact O-CB 3.37Å; A1035-A1039 PolarHBondContact O-N 3.24Å; Q1036-A1039 PolarHBondContact O-N 3.16Å; M1037-A1039 PolarHBondContact O-N 3.27Å; A1039-N1043 WeakPolarHBondContact O-CB 3.29Å; A1039-N1043 PolarHBondContact O-N 3.23Å; A1039-N1043 PolarHBondContact O-ND2 3.17Å
1040L57.2Low57.3Low117 Ų117112.3 Ų112.361%0.61356%0.56SS**Hα-helixtrans-68.5-41.8171.7-76.7164.7000111Q1036 M1037 N1043 F1044Q1036-L1040 WeakPolarHBondContact O-CB 3.48Å; Q1036-L1040 WeakPolarHBondContact O-CG 3.21Å; Q1036-L1040 PolarHBondContact O-N 3.14Å; M1037-L1040 PolarHBondContact O-N 3.07Å; L1040-N1043 PolarHBondContact O-N 3.47Å; L1040-F1044 WeakPolarHBondContact O-CB 3.28Å; L1040-F1044 PolarHBondContact O-N 3.45Å
1041Q50.3Low56.8Low130 Ų130112.6 Ų112.661%0.60757%0.57SS**Hα-helixtrans-66.4-39.2177.3-158.717317.100111.7M1037 S1038 F1044 I1045M1037-Q1041 VanDerWaalsContact O-CB 3.32Å; M1037-Q1041 WeakPolarHBondContact O-CB 3.43Å; M1037-Q1041 PolarHBondContact O-N 3.32Å; S1038-Q1041 PolarHBondContact O-N 3.01Å; Q1041-F1044 PolarHBondContact O-N 3.03Å; Q1041-I1045 WeakPolarHBondContact O-CD1 3.33Å; Q1041-I1045 VanDerWaalsContact O-CG1 3.27Å; Q1041-I1045 WeakPolarHBondContact O-CG1 3.23Å; Q1041-I1045 PolarHBondContact O-N 3.23Å
1042K57.5Low55.8Low147 Ų147116.7 Ų116.764%0.63958%0.582SS**Hα-helixtrans-63.8-45.6170.1-96.4-172171.2-174.90112.7S1038 F1044 I1045 E1046S1038-K1042 WeakPolarHBondContact O-CB 3.44Å; S1038-K1042 PolarHBondContact O-N 3.3Å; K1042-F1044 VanDerWaalsContact C-N 3.3Å; K1042-F1044 PolarHBondContact O-N 3.33Å; K1042-I1045 PolarHBondContact O-N 3.15Å; K1042-E1046 WeakPolarHBondContact O-CG 3.29Å; K1042-E1046 PolarHBondContact O-N 3.23Å
1043N58.6Low54.9Low99 Ų99116 Ų11653%0.52959%0.586SS.*Hα-helixtrans-60.3-40.4175.9-90.2-67.6000111.9A1039 L1040 E1046 T1047A1039-N1043 WeakPolarHBondContact O-CB 3.29Å; A1039-N1043 PolarHBondContact O-N 3.23Å; A1039-N1043 PolarHBondContact O-ND2 3.17Å; L1040-N1043 PolarHBondContact O-N 3.47Å; N1043-E1046 PolarHBondContact O-N 2.88Å; N1043-T1047 PolarHBondContact O-N 3.2Å; N1043-T1047 PolarHBondContact O-OG1 3.26Å
1044F49.5Very low54Low124 Ų124120.1 Ų120.154%0.54461%0.609SS.*Hα-helixtrans-63.8-40.3176.5-172.6-98.9000112.6L1040 Q1041 K1042 E1046 T1047 H1048L1040-F1044 WeakPolarHBondContact O-CB 3.28Å; L1040-F1044 PolarHBondContact O-N 3.45Å; Q1041-F1044 PolarHBondContact O-N 3.03Å; K1042-F1044 VanDerWaalsContact C-N 3.3Å; K1042-F1044 PolarHBondContact O-N 3.33Å; F1044-E1046 VanDerWaalsContact C-N 3.35Å; F1044-T1047 WeakPolarHBondContact CA-OG1 3.46Å; F1044-T1047 PolarHBondContact O-OG1 2.98Å; F1044-H1048 AromaticContact CE2-CD2 3.73Å; F1044-H1048 AromaticContact CE2-NE2 3.74Å; F1044-H1048 AromaticContact CZ-CD2 3.61Å; F1044-H1048 PolarHBondContact O-N 3.32Å
1045I59Low53Low102 Ų102120 Ų12052%0.52362%0.615SS.*Hα-helixtrans-67.1-36.3174.2-68.1163.8000111Q1041 K1042 K1049Q1041-I1045 WeakPolarHBondContact O-CD1 3.33Å; Q1041-I1045 VanDerWaalsContact O-CG1 3.27Å; Q1041-I1045 WeakPolarHBondContact O-CG1 3.23Å; Q1041-I1045 PolarHBondContact O-N 3.23Å; K1042-I1045 PolarHBondContact O-N 3.15Å; I1045-K1049 PolarHBondContact O-N 2.95Å
1046E57.3Low51.4Low119 Ų119122.6 Ų122.656%0.55663%0.63SS**Hα-helixtrans-75.6-30176.8-69.6-164.2124.600114K1042 N1043 F1044 K1049K1042-E1046 WeakPolarHBondContact O-CG 3.29Å; K1042-E1046 PolarHBondContact O-N 3.23Å; N1043-E1046 PolarHBondContact O-N 2.88Å; F1044-E1046 VanDerWaalsContact C-N 3.35Å; E1046-K1049 IonicContact OE1-NZ 2.62Å; E1046-K1049 PolarHBondContact OE1-NZ 2.62Å
1047T54.8Low50.2Low101 Ų101126.3 Ų126.362%0.6265%0.648SS**Hα-helixtrans-77.7-15.9172.541.30000114.2N1043 F1044N1043-T1047 PolarHBondContact O-N 3.2Å; N1043-T1047 PolarHBondContact O-OG1 3.26Å; F1044-T1047 WeakPolarHBondContact CA-OG1 3.46Å; F1044-T1047 PolarHBondContact O-OG1 2.98Å
1048H56.5Low49.3Very low89 Ų89128.8 Ų128.841%0.41266%0.66SS.*THydrogen-bonded Turntrans-120.623.5-179.6-65.1-11.5000113.6F1044 L1050 M1051F1044-H1048 AromaticContact CE2-CD2 3.73Å; F1044-H1048 AromaticContact CE2-NE2 3.74Å; F1044-H1048 AromaticContact CZ-CD2 3.61Å; F1044-H1048 PolarHBondContact O-N 3.32Å; H1048-L1050 PolarHBondContact O-N 2.71Å; H1048-M1051 PolarHBondContact O-N 3.27Å
1049K46.1Very low48.3Very low119 Ų119131.2 Ų131.252%0.51767%0.674SS.*THydrogen-bonded Turntrans-62-7.6-172.8-140.7171.2-170.9167.30116.3I1045 E1046I1045-K1049 PolarHBondContact O-N 2.95Å; E1046-K1049 IonicContact OE1-NZ 2.62Å; E1046-K1049 PolarHBondContact OE1-NZ 2.62Å
1050L52.1Low46.5Very low168 Ų168132.4 Ų132.488%0.8869%0.691SS**THydrogen-bonded Turntrans-102.3-1.1-177.6-92.5159.9000114.8H1048H1048-L1050 PolarHBondContact O-N 2.71Å
1051M47Very low45Very low166 Ų166135.2 Ų135.282%0.81870%0.698SS**SBendtrans-106.72.4177.9-70.7-147.3-83.900114.9H1048H1048-M1051 PolarHBondContact O-N 3.27Å
1052Y47.4Very low43.8Very low197 Ų197135.8 Ų135.877%0.77370%0.701SS**SBendtrans-117.5-3.3-176.4-80.7-80000115.6N1054Y1052-N1054 PolarHBondContact O-N 3.13Å
1053D45Very low42.4Very low135 Ų135135.5 Ų135.572%0.72271%0.706SS**SBendtrans-82.7-3.8-175.2-82.2-5.1000115
1054N41.2Very low40.8Very low160 Ų160135.5 Ų135.586%0.85671%0.714SS**SBendtrans-112.846-177.5-78.4-15.4000113.8Y1052Y1052-N1054 PolarHBondContact O-N 3.13Å
1055T36.1Very low39.8Very low129 Ų129136.6 Ų136.679%0.79172%0.724SS**  trans-154.470.4162.5-6.50000114.5
1056S32.9Very low38.3Very low117 Ų117138.6 Ų138.682%0.81873%0.733SS**  trans-166.5118.4146.2-94.10000112
1057E29.6Very low36.9Very low196 Ų196140 Ų14092%0.91674%0.739SS**  -168.9129.7115.4-101.9172-169.800109.9
1058M32.1Very low35.7Very low176 Ų176143.1 Ų143.187%0.86775%0.747SS**  trans-90.1179.7164.8-62.1-129.8-5700108.7
1059P39.8Very low34.3Very low117 Ų117145.6 Ų145.676%0.7676%0.759SS**  cis-136.4173.6-2.140-22.7000115.9
1060G25.8Very low33.6Very low73 Ų73153.7 Ų153.775%0.75379%0.786SS**  trans113.9126.1131.100000120.8
1061K26.3Very low32.7Very low175 Ų175153 Ų15376%0.76178%0.782SS**  trans77.4127.5145.7-85.9-172.2161.5-136.90123.1
1062E26.3Very low31.9Very low143 Ų143152.3 Ų152.367%0.66878%0.78SS**  trans91.2133136.2-76.6162-169.500121.5
1063D26.5Very low31.1Very low140 Ų140149.8 Ų149.875%0.74978%0.78SS**  trans71.490.1156.2-60.8-7.5000123.6
1064S25.9Very low30.2Very low100 Ų100150.7 Ų150.770%0.69978%0.784SS**  97149.4106.780.40000121.6
1065I27.5Very low29.6Very low146 Ų146150.1 Ų150.175%0.74978%0.779SS**  trans84.9128.9160.3-59.8165000117.7
1066M27.7Very low29.1Very low145 Ų145151.5 Ų151.571%0.71478%0.778SS**  trans4.4153.2151.3-61144.955.900119.2
1067E28.3Very low28.9Very low147 Ų147154 Ų15469%0.68778%0.775SS**  cis-167.1161.432.6-142.5149.4-160.900111.8
1068E29.1Very low28.8Very low168 Ų168150.8 Ų150.879%0.78577%0.765SS**  trans57.6131.8149-85174.5174.900126.6
1069E27.8Very low28.5Very low140 Ų140148.7 Ų148.765%0.65476%0.756SS**  trans77109.6141.7-69.6-130.4153.300123.9
1070R31.3Very low27.5Very low290 Ų290151.5 Ų151.5100%1.09476%0.756SS**  trans90.10147.1-61.2176.6-164.6-138.1-3.8119.8

Retrieved 1,070 of 1,070 residues in 461.2 ms (Link to these results)