A0A087WTS9_HUMAN Loading...

Cone-rod homeobox

AlphaFold DB , UniProt , Accession A0A087WTS9, Species HUMAN (Homo sapiens, Human), Gene CRX, Length 41 aa.

						>A0A087WTS9_HUMAN|A0A087WTS9|CRX
MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSLVQEPEG
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	55.3	Low	67.9	Low	228 Å²	228	144.9 Å²	144.9	100%	1.123	75%	0.745	S	S	*	*				0	100.2	0	-173.2	76.2	175.4	107.3
2	M	65.9	Low	68.3	Low	167 Å²	167	141.9 Å²	141.9	82%	0.823	75%	0.746	S	S	*	*			trans	-94.3	119.8	171.5	-66.4	-59.2	-172.3	106.8	Y4	M2-Y4 PolarHBondContact O-N 3.18Å; M2-Y4 WeakPolarHBondContact O-CD2 3.49Å
3	A	66.2	Low	68.2	Low	82 Å²	82	139.8 Å²	139.8	68%	0.678	74%	0.742	S	S	*	*			trans	-65.2	117.1	178.4	0	0	0	108.7	M5	A3-M5 PolarHBondContact O-N 3.31Å; A3-M5 VanDerWaalsContact C-N 3.3Å
4	Y	68.4	Low	68.3	Low	226 Å²	226	138.3 Å²	138.3	89%	0.886	73%	0.734	S	S	*	*			trans	-69.9	91.6	172.3	-63.5	-93	0	107.5	M2 N6	M2-Y4 PolarHBondContact O-N 3.18Å; M2-Y4 WeakPolarHBondContact O-CD2 3.49Å; Y4-N6 PolarHBondContact O-N 3.06Å
5	M	70.9	Confident	67.9	Low	168 Å²	168	134.3 Å²	134.3	83%	0.828	73%	0.729	S	S	*	*			trans	-67.9	114.7	170.6	-63	-125.6	100.3	107	A3 P7	A3-M5 PolarHBondContact O-N 3.31Å; A3-M5 VanDerWaalsContact C-N 3.3Å; M5-P7 WeakPolarHBondContact O-CD 3.13Å
6	N	68.8	Low	67.5	Low	145 Å²	145	135.6 Å²	135.6	78%	0.775	73%	0.734	S	S	*	*			trans	-76.2	107.4	169.1	-179.7	11.7	0	107.2	Y4 G8	Y4-N6 PolarHBondContact O-N 3.06Å; N6-G8 PolarHBondContact O-N 2.88Å
7	P	68.3	Low	67.2	Low	93 Å²	93	132.4 Å²	132.4	60%	0.604	73%	0.73	S	S	*	*			trans	-75.4	82.8	171.3	32.9	-27.9	0	106	M5 H10	M5-P7 WeakPolarHBondContact O-CD 3.13Å; P7-H10 VanDerWaalsContact CB-NE2 3.3Å; P7-H10 WeakPolarHBondContact CB-NE2 3.28Å
8	G	73.2	Confident	66.9	Low	33 Å²	33	132.4 Å²	132.4	34%	0.34	73%	0.728	S	S	.	*			trans	-49.4	159.1	168.1	0	0	0	110	N6 H10	N6-G8 PolarHBondContact O-N 2.88Å; G8-H10 PolarHBondContact O-CD2 2.76Å; G8-H10 PolarHBondContact O-N 2.86Å
9	P	68.1	Low	66.6	Low	97 Å²	97	128.9 Å²	128.9	63%	0.63	71%	0.714	S	S	*	*			trans	-51.8	112.1	-169.8	19.5	-31.3	0	111.4	Y11	P9-Y11 PolarHBondContact O-N 2.81Å; P9-Y11 VanDerWaalsContact O-N 3.13Å; P9-Y11 WeakPolarHBondContact O-CD2 3.37Å; P9-Y11 VanDerWaalsContact O-CD2 3.3Å; P9-Y11 HydrophobicContact CB-CE2 3.75Å; P9-Y11 HydrophobicContact CB-CE1 4.44Å; P9-Y11 HydrophobicContact CB-CD2 4.42Å; P9-Y11 HydrophobicContact CG-CE2 3.78Å
10	H	69	Low	66.4	Low	157 Å²	157	124.1 Å²	124.1	73%	0.727	70%	0.695	S	S	*	*			trans	-80.4	91.9	177.7	-71.1	-91.8	0	108.1	P7 G8 S12	P7-H10 VanDerWaalsContact CB-NE2 3.3Å; P7-H10 WeakPolarHBondContact CB-NE2 3.28Å; G8-H10 PolarHBondContact O-CD2 2.76Å; G8-H10 PolarHBondContact O-N 2.86Å; H10-S12 PolarHBondContact O-N 3.02Å
11	Y	72.8	Confident	66.1	Low	198 Å²	198	123.8 Å²	123.8	78%	0.776	70%	0.699	S	S	*	*			trans	-75	103.5	171.1	-57.8	-78	0	108.6	P9 V13	P9-Y11 PolarHBondContact O-N 2.81Å; P9-Y11 VanDerWaalsContact O-N 3.13Å; P9-Y11 WeakPolarHBondContact O-CD2 3.37Å; P9-Y11 VanDerWaalsContact O-CD2 3.3Å; P9-Y11 HydrophobicContact CB-CE2 3.75Å; P9-Y11 HydrophobicContact CB-CE1 4.44Å; P9-Y11 HydrophobicContact CB-CD2 4.42Å; P9-Y11 HydrophobicContact CG-CE2 3.78Å; Y11-V13 PolarHBondContact O-N 2.84Å
12	S	72.4	Confident	66.1	Low	109 Å²	109	117.2 Å²	117.2	76%	0.762	68%	0.675	S	S	*	*			trans	-75.4	109	171.6	59.2	0	0	109.1	H10	H10-S12 PolarHBondContact O-N 3.02Å
13	V	67.8	Low	65.6	Low	115 Å²	115	112.6 Å²	112.6	70%	0.697	66%	0.656	S	S	*	*			trans	-77.2	123.5	168.9	-105.5	0	0	108.9	Y11 A15	Y11-V13 PolarHBondContact O-N 2.84Å; V13-A15 PolarHBondContact O-N 3.29Å
14	N	69.1	Low	65.1	Low	118 Å²	118	113.7 Å²	113.7	63%	0.631	65%	0.65	S	S	*	*			trans	-62.5	122.7	173.5	-70.9	-25.7	0	108.7	L16 A17	N14-L16 PolarHBondContact O-N 3.27Å; N14-L16 VanDerWaalsContact O-N 3.12Å; N14-A17 HydrophobicContact CB-CB 4.36Å; N14-A17 PolarHBondContact O-N 3.46Å; N14-A17 WeakPolarHBondContact O-CB 3.46Å; N14-A17 VanDerWaalsContact O-CB 3.29Å; N14-A17 WeakPolarHBondContact O-CA 3.48Å
15	A	62	Low	64.6	Low	79 Å²	79	109.5 Å²	109.5	65%	0.653	64%	0.643	S	S	*	*	H	α-helix	trans	-57.5	-28.2	176.8	0	0	0	112.3	V13 A17 L18 S19	V13-A15 PolarHBondContact O-N 3.29Å; A15-A17 PolarHBondContact O-N 3.35Å; A15-L18 WeakPolarHBondContact O-CB 3.29Å; A15-L18 PolarHBondContact O-N 3.24Å; A15-S19 PolarHBondContact O-N 3.28Å; A15-S19 VanDerWaalsContact O-N 3.16Å
16	L	61.4	Low	63.9	Low	154 Å²	154	108.9 Å²	108.9	81%	0.806	64%	0.64	S	S	*	*	H	α-helix	trans	-63.6	-25.2	172	-124.9	91.2	0	113.7	N14 L18 S19	N14-L16 PolarHBondContact O-N 3.27Å; N14-L16 VanDerWaalsContact O-N 3.12Å; L16-L18 VanDerWaalsContact C-N 3.29Å; L16-S19 PolarHBondContact O-OG 3.41Å
17	A	63.2	Low	63.4	Low	81 Å²	81	108.5 Å²	108.5	67%	0.669	63%	0.633	S	S	*	*	H	α-helix	trans	-79.8	-15.1	173.9	0	0	0	112.2	N14 A15	N14-A17 HydrophobicContact CB-CB 4.36Å; N14-A17 PolarHBondContact O-N 3.46Å; N14-A17 WeakPolarHBondContact O-CB 3.46Å; N14-A17 VanDerWaalsContact O-CB 3.29Å; N14-A17 WeakPolarHBondContact O-CA 3.48Å; A15-A17 PolarHBondContact O-N 3.35Å
18	L	61.1	Low	62.8	Low	133 Å²	133	111.6 Å²	111.6	70%	0.696	64%	0.639	S	S	*	*	H	α-helix	trans	-95.3	-15.2	174.8	-62.8	173.4	0	112.5	A15 L16 G20	A15-L18 WeakPolarHBondContact O-CB 3.29Å; A15-L18 PolarHBondContact O-N 3.24Å; L16-L18 VanDerWaalsContact C-N 3.29Å; L18-G20 PolarHBondContact O-N 3.4Å
19	S	61.7	Low	62	Low	66 Å²	66	113.5 Å²	113.5	46%	0.462	65%	0.652	S	S	.	*			trans	-72.8	76.1	166.8	63.6	0	0	109	A15 L16	A15-S19 PolarHBondContact O-N 3.28Å; A15-S19 VanDerWaalsContact O-N 3.16Å; L16-S19 PolarHBondContact O-OG 3.41Å
20	G	62.2	Low	61.5	Low	32 Å²	32	114.2 Å²	114.2	33%	0.33	65%	0.654	S	S	.	*			trans	-68.3	171.2	170.6	0	0	0	111.8	L18 S22 V23	L18-G20 PolarHBondContact O-N 3.4Å; G20-S22 PolarHBondContact O-N 3.18Å; G20-V23 PolarHBondContact O-N 2.78Å
21	P	59.6	Low	61.3	Low	119 Å²	119	112 Å²	112	77%	0.773	65%	0.653	S	S	*	*	T	Hydrogen-bonded Turn	trans	-57	-9.3	-178.2	20.5	-31.5	0	114.9	V23 D24	P21-V23 VanDerWaalsContact C-N 3.29Å; P21-V23 PolarHBondContact O-N 2.84Å; P21-D24 PolarHBondContact O-N 2.87Å
22	S	56.9	Low	60.6	Low	89 Å²	89	112.5 Å²	112.5	62%	0.622	66%	0.655	S	S	*	*	H	α-helix	trans	-69.8	-18.3	176	-44.3	0	0	114.6	G20	G20-S22 PolarHBondContact O-N 3.18Å
23	V	54.5	Low	59.8	Low	70 Å²	70	112.3 Å²	112.3	42%	0.424	65%	0.652	S	S	.	*	H	α-helix	trans	-73.5	-30	175.8	172.3	0	0	111.4	G20 P21 M26 H27	G20-V23 PolarHBondContact O-N 2.78Å; P21-V23 VanDerWaalsContact C-N 3.29Å; P21-V23 PolarHBondContact O-N 2.84Å; V23-M26 PolarHBondContact O-N 3.16Å; V23-H27 WeakPolarHBondContact CG1-CE1 3.3Å; V23-H27 WeakPolarHBondContact CG1-ND1 3.3Å; V23-H27 PolarHBondContact O-N 3.35Å; V23-H27 PolarHBondContact O-ND1 3.12Å
24	D	56.8	Low	59.5	Low	106 Å²	106	112.1 Å²	112.1	57%	0.567	66%	0.655	S	S	*	*	H	α-helix	trans	-67.1	-39.7	177.2	-165.6	39.4	0	111.3	P21 M26 H27 Q28	P21-D24 PolarHBondContact O-N 2.87Å; D24-M26 PolarHBondContact O-N 3.03Å; D24-M26 VanDerWaalsContact C-N 3.33Å; D24-H27 PolarHBondContact O-N 2.83Å; D24-Q28 PolarHBondContact O-N 3.26Å
25	L	56.2	Low	58.9	Low	138 Å²	138	113.4 Å²	113.4	72%	0.723	66%	0.661	S	S	*	*	H	α-helix	trans	-64.1	-33.4	177.7	-118.3	88.2	0	113.8
26	M	57	Low	58.6	Low	155 Å²	155	115.5 Å²	115.5	76%	0.764	67%	0.666	S	S	*	*	H	α-helix	trans	-82.1	-22.6	-179.8	-62.9	-71.2	-84.3	112.3	V23 D24	V23-M26 PolarHBondContact O-N 3.16Å; D24-M26 PolarHBondContact O-N 3.03Å; D24-M26 VanDerWaalsContact C-N 3.33Å
27	H	58.1	Low	58.6	Low	136 Å²	136	116.7 Å²	116.7	63%	0.63	67%	0.667	S	S	*	*	H	α-helix	trans	-83.3	-31.4	173.2	-73.1	111.6	0	112.8	V23 D24 A29	V23-H27 WeakPolarHBondContact CG1-CE1 3.3Å; V23-H27 WeakPolarHBondContact CG1-ND1 3.3Å; V23-H27 PolarHBondContact O-N 3.35Å; V23-H27 PolarHBondContact O-ND1 3.12Å; D24-H27 PolarHBondContact O-N 2.83Å; H27-A29 PolarHBondContact O-N 3.2Å
28	Q	55	Low	58.4	Low	159 Å²	159	119.7 Å²	119.7	74%	0.743	67%	0.667	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74	-5.6	179.2	-142.5	-171.8	-75.4	113.7	D24	D24-Q28 PolarHBondContact O-N 3.26Å
29	A	56.2	Low	58.4	Low	73 Å²	73	118.7 Å²	118.7	60%	0.603	67%	0.669	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.6	11.3	-179.3	0	0	0	114.3	H27 P31	H27-A29 PolarHBondContact O-N 3.2Å; A29-P31 WeakPolarHBondContact O-CD 3.18Å
30	V	59.1	Low	58.4	Low	112 Å²	112	124.1 Å²	124.1	68%	0.679	69%	0.687	S	S	*	*			trans	-96.3	100.3	170.1	-167.4	0	0	108.6	Y32	V30-Y32 PolarHBondContact O-N 3.28Å
31	P	64.3	Low	58.1	Low	109 Å²	109	129.8 Å²	129.8	71%	0.708	75%	0.745	S	S	*	*			trans	-61.1	128.6	169.4	24.2	-30.3	0	108.5	A29	A29-P31 WeakPolarHBondContact O-CD 3.18Å
32	Y	58.8	Low	58	Low	210 Å²	210	130.4 Å²	130.4	82%	0.824	74%	0.744	S	S	*	*			trans	-52.7	129.4	163.6	-95.1	-95.1	0	107.6	V30 S34	V30-Y32 PolarHBondContact O-N 3.28Å; Y32-S34 VanDerWaalsContact C-N 3.35Å; Y32-S34 PolarHBondContact O-N 3.13Å
33	P	56	Low	58.1	Low	105 Å²	105	132.5 Å²	132.5	68%	0.682	75%	0.75	S	S	*	*			trans	-60.7	109.5	163.2	26	-29.3	0	105.4	L35	P33-L35 PolarHBondContact O-N 2.85Å
34	S	59.7	Low	58.3	Low	110 Å²	110	136 Å²	136	77%	0.769	77%	0.769	S	S	*	*			trans	-64.5	84.8	163.3	-67.9	0	0	105.6	Y32 V36	Y32-S34 VanDerWaalsContact C-N 3.35Å; Y32-S34 PolarHBondContact O-N 3.13Å; S34-V36 PolarHBondContact O-N 2.9Å
35	L	56.5	Low	58.4	Low	146 Å²	146	137.8 Å²	137.8	76%	0.764	78%	0.78	S	S	*	*			trans	-62.9	94.2	155.8	-75.6	176.6	0	104.2	P33 Q37	P33-L35 PolarHBondContact O-N 2.85Å; L35-Q37 PolarHBondContact O-N 3.09Å
36	V	56.8	Low	58.5	Low	122 Å²	122	137.8 Å²	137.8	74%	0.739	78%	0.784	S	S	*	*			trans	-55.4	96.3	164.5	-176.7	0	0	104.9	S34 E38	S34-V36 PolarHBondContact O-N 2.9Å; V36-E38 VanDerWaalsContact C-N 3.29Å; V36-E38 PolarHBondContact O-N 3.21Å
37	Q	60.5	Low	58.6	Low	180 Å²	180	136.6 Å²	136.6	84%	0.841	79%	0.785	S	S	*	*			trans	-76	93.2	163.5	-72.3	176.5	91.3	104.9	L35 P39	L35-Q37 PolarHBondContact O-N 3.09Å; Q37-P39 WeakPolarHBondContact O-CD 3.44Å
38	E	58.6	Low	58.6	Low	143 Å²	143	136.6 Å²	136.6	67%	0.668	80%	0.797	S	S	*	*			trans	-96	110.7	156.6	-168.2	171.3	119.7	106.7	V36 E40	V36-E38 VanDerWaalsContact C-N 3.29Å; V36-E38 PolarHBondContact O-N 3.21Å; E38-E40 PolarHBondContact O-N 3.19Å
39	P	62.9	Low	58.9	Low	113 Å²	113	134.9 Å²	134.9	73%	0.734	80%	0.801	S	S	*	*			trans	-72.3	110	162.6	28.3	-26.7	0	107.1	Q37 G41	Q37-P39 WeakPolarHBondContact O-CD 3.44Å; P39-G41 PolarHBondContact O-N 2.92Å
40	E	60.7	Low	59.1	Low	180 Å²	180	140.1 Å²	140.1	84%	0.841	82%	0.817	S	S	*	*			trans	-61.1	110.8	168.1	-60.9	-130.9	136.8	108.1	E38	E38-E40 PolarHBondContact O-N 3.19Å
41	G	55.9	Low	59.1	Low	151 Å²	151	142.6 Å²	142.6	100%	1.557	83%	0.83	S	S	*	*			trans	-96.2	0	167.7	0	0	0	110.7	P39	P39-G41 PolarHBondContact O-N 2.92Å

Retrieved 41 of 41 residues in 11.9 ms (Link to these results)

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