A0A087WUG0_HUMAN Loading...

Tubulin tyrosine ligase like 5

AlphaFold DB , UniProt , Accession A0A087WUG0, Species HUMAN (Homo sapiens, Human), Gene TTLL5, Length 60 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1N86Confident93.2Very high144 Ų144103.6 Ų103.677%0.7755%0.551SS**  0115.60-177.4-33.1000108L3 T4 Q5N1-L3 WeakPolarHBondContact OD1-CB 3.39Å; N1-L3 PolarHBondContact OD1-N 3.39Å; N1-T4 WeakPolarHBondContact CB-OG1 3.4Å; N1-T4 PolarHBondContact ND2-OG1 3.25Å; N1-T4 PolarHBondContact OD1-N 2.94Å; N1-T4 VanDerWaalsContact OD1-N 3.11Å; N1-T4 PolarHBondContact OD1-OG1 3.27Å; N1-Q5 PolarHBondContact O-N 2.78Å
2L96Very high92.7Very high128 Ų128103.8 Ų103.867%0.6755%0.552SS**Hα-helixtrans-68.8-37.8-177.3177.762.3000112.2T4 Q5 Q6L2-T4 VanDerWaalsContact C-N 3.35Å; L2-T4 PolarHBondContact O-N 3.18Å; L2-Q5 WeakPolarHBondContact O-CB 3.37Å; L2-Q5 PolarHBondContact O-N 2.97Å; L2-Q6 WeakPolarHBondContact O-CG 3.47Å; L2-Q6 PolarHBondContact O-N 2.93Å
3L96.6Very high92Very high113 Ų113100.2 Ų100.259%0.59255%0.545SS*.Hα-helixtrans-63-41.9177.1179.966.9000111.2N1 Q5 Q6 V7N1-L3 WeakPolarHBondContact OD1-CB 3.39Å; N1-L3 PolarHBondContact OD1-N 3.39Å; L3-Q5 PolarHBondContact O-N 3.06Å; L3-Q6 PolarHBondContact O-N 3.07Å; L3-V7 WeakPolarHBondContact O-CG2 3.47Å; L3-V7 PolarHBondContact O-N 3.12Å
4T94.8Very high91Very high77 Ų7798 Ų9847%0.47254%0.537SS..Hα-helixtrans-59.6-45.5175.2-51.50000111.5N1 L2 Q6 V7 T8N1-T4 WeakPolarHBondContact CB-OG1 3.4Å; N1-T4 PolarHBondContact ND2-OG1 3.25Å; N1-T4 PolarHBondContact OD1-N 2.94Å; N1-T4 VanDerWaalsContact OD1-N 3.11Å; N1-T4 PolarHBondContact OD1-OG1 3.27Å; L2-T4 VanDerWaalsContact C-N 3.35Å; L2-T4 PolarHBondContact O-N 3.18Å; T4-Q6 VanDerWaalsContact C-N 3.32Å; T4-Q6 PolarHBondContact O-N 2.98Å; T4-V7 PolarHBondContact O-N 3.39Å; T4-T8 WeakPolarHBondContact O-CB 3.2Å; T4-T8 PolarHBondContact O-N 2.95Å; T4-T8 PolarHBondContact O-OG1 2.99Å; T4-T8 VanDerWaalsContact O-OG1 3.06Å
5Q96.3Very high89.5Confident122 Ų12293.5 Ų93.557%0.5752%0.522SS*.Hα-helixtrans-60.5-40.5176.3-75.7-94.484.900112N1 L2 L3 T8 N9N1-Q5 PolarHBondContact O-N 2.78Å; L2-Q5 WeakPolarHBondContact O-CB 3.37Å; L2-Q5 PolarHBondContact O-N 2.97Å; L3-Q5 PolarHBondContact O-N 3.06Å; Q5-T8 PolarHBondContact O-N 2.99Å; Q5-N9 WeakPolarHBondContact O-CB 3.45Å; Q5-N9 VanDerWaalsContact O-CG 3.31Å; Q5-N9 PolarHBondContact O-N 3.16Å; Q5-N9 PolarHBondContact O-ND2 3.48Å
6Q94.9Very high87.8Confident108 Ų10894.9 Ų94.951%0.50553%0.526SS..Hα-helixtrans-65.1-46178.1-70.8178.931.500112L2 L3 T4 T8 N9 L10L2-Q6 WeakPolarHBondContact O-CG 3.47Å; L2-Q6 PolarHBondContact O-N 2.93Å; L3-Q6 PolarHBondContact O-N 3.07Å; T4-Q6 VanDerWaalsContact C-N 3.32Å; T4-Q6 PolarHBondContact O-N 2.98Å; Q6-T8 VanDerWaalsContact C-N 3.34Å; Q6-T8 PolarHBondContact O-N 2.96Å; Q6-N9 PolarHBondContact O-N 2.69Å; Q6-L10 WeakPolarHBondContact O-CB 3.39Å; Q6-L10 PolarHBondContact O-N 2.85Å
7V94.4Very high86.1Confident74 Ų7497.1 Ų97.145%0.44854%0.535SS..Hα-helixtrans-63.8-40.9178.31740000110.8L3 T4 L10 N11L3-V7 WeakPolarHBondContact O-CG2 3.47Å; L3-V7 PolarHBondContact O-N 3.12Å; T4-V7 PolarHBondContact O-N 3.39Å; V7-L10 PolarHBondContact O-N 3.36Å; V7-N11 WeakPolarHBondContact CG1-ND2 3.35Å; V7-N11 PolarHBondContact O-N 2.98Å; V7-N11 PolarHBondContact O-ND2 2.95Å
8T93.7Very high84.5Confident65 Ų65100.1 Ų100.140%0.39955%0.55SS.*Hα-helixtrans-63.3-48.3176.8-63.10000111.9T4 Q5 Q6 L10 N11 L12T4-T8 WeakPolarHBondContact O-CB 3.2Å; T4-T8 PolarHBondContact O-N 2.95Å; T4-T8 PolarHBondContact O-OG1 2.99Å; T4-T8 VanDerWaalsContact O-OG1 3.06Å; Q5-T8 PolarHBondContact O-N 2.99Å; Q6-T8 VanDerWaalsContact C-N 3.34Å; Q6-T8 PolarHBondContact O-N 2.96Å; T8-L10 VanDerWaalsContact C-N 3.33Å; T8-L10 PolarHBondContact O-N 3.45Å; T8-N11 PolarHBondContact O-N 3.21Å; T8-L12 HydrophobicContact CG2-CD1 3.76Å; T8-L12 WeakPolarHBondContact O-CD1 3.38Å; T8-L12 WeakPolarHBondContact O-CG 3.29Å; T8-L12 PolarHBondContact O-N 2.81Å
9N92.4Very high83Confident96 Ų96105.2 Ų105.251%0.51356%0.56SS.*Hα-helixtrans-62.3-38.8178.5-74.1-29.9000112.6Q5 Q6 L12 A13Q5-N9 WeakPolarHBondContact O-CB 3.45Å; Q5-N9 VanDerWaalsContact O-CG 3.31Å; Q5-N9 PolarHBondContact O-N 3.16Å; Q5-N9 PolarHBondContact O-ND2 3.48Å; Q6-N9 PolarHBondContact O-N 2.69Å; N9-L12 PolarHBondContact O-N 3.14Å; N9-A13 WeakPolarHBondContact O-CB 3.4Å; N9-A13 PolarHBondContact O-N 3.17Å
10L91.8Very high81.7Confident113 Ų113104.8 Ų104.859%0.59257%0.566SS**Hα-helixtrans-62.3-47.3175.1-179.360.3000111.4Q6 V7 T8 L12 A13 T14Q6-L10 WeakPolarHBondContact O-CB 3.39Å; Q6-L10 PolarHBondContact O-N 2.85Å; V7-L10 PolarHBondContact O-N 3.36Å; T8-L10 VanDerWaalsContact C-N 3.33Å; T8-L10 PolarHBondContact O-N 3.45Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3.39Å; L10-A13 PolarHBondContact O-N 2.92Å; L10-T14 HydrophobicContact CD1-CG2 4.12Å; L10-T14 VanDerWaalsContact O-CG2 3.29Å; L10-T14 WeakPolarHBondContact O-CG2 3.33Å; L10-T14 PolarHBondContact O-N 3.46Å; L10-T14 PolarHBondContact O-OG1 3.42Å; L10-T14 VanDerWaalsContact O-OG1 3.14Å
11N88.8Confident80.6Confident100 Ų100104.9 Ų104.954%0.53558%0.575SS.*Hα-helixtrans-64-36178.3-78-64.2000113V7 T8 T14 G15V7-N11 WeakPolarHBondContact CG1-ND2 3.35Å; V7-N11 PolarHBondContact O-N 2.98Å; V7-N11 PolarHBondContact O-ND2 2.95Å; T8-N11 PolarHBondContact O-N 3.21Å; N11-T14 WeakPolarHBondContact CA-OG1 3.36Å; N11-T14 PolarHBondContact O-OG1 3.41Å; N11-G15 PolarHBondContact O-N 3.02Å
12L87Confident79.3Confident106 Ų106102.3 Ų102.356%0.55557%0.574SS**Hα-helixtrans-63.9-47.7174.1-74.8157000110.9T8 N9 L10 G15 I16T8-L12 HydrophobicContact CG2-CD1 3.76Å; T8-L12 WeakPolarHBondContact O-CD1 3.38Å; T8-L12 WeakPolarHBondContact O-CG 3.29Å; T8-L12 PolarHBondContact O-N 2.81Å; N9-L12 PolarHBondContact O-N 3.14Å; L10-L12 VanDerWaalsContact C-N 3.33Å; L10-L12 PolarHBondContact O-N 3.39Å; L12-G15 PolarHBondContact O-N 3.26Å; L12-I16 WeakPolarHBondContact O-CG1 3.42Å; L12-I16 PolarHBondContact O-N 3.36Å
13A83.4Confident77.3Confident56 Ų56101.5 Ų101.546%0.46358%0.578SS.*Hα-helixtrans-63.8-41.8179.900000112.3N9 L10 I17N9-A13 WeakPolarHBondContact O-CB 3.4Å; N9-A13 PolarHBondContact O-N 3.17Å; L10-A13 PolarHBondContact O-N 2.92Å; A13-I17 WeakPolarHBondContact O-CD1 3.44Å; A13-I17 WeakPolarHBondContact O-CG1 3.49Å
14T78.6Confident75.6Confident70 Ų7099.6 Ų99.643%0.42958%0.579SS.*Hα-helixtrans-72.8-34.4-179.858.80000112.7L10 N11 I16 I17 N18L10-T14 HydrophobicContact CD1-CG2 4.12Å; L10-T14 VanDerWaalsContact O-CG2 3.29Å; L10-T14 WeakPolarHBondContact O-CG2 3.33Å; L10-T14 PolarHBondContact O-N 3.46Å; L10-T14 PolarHBondContact O-OG1 3.42Å; L10-T14 VanDerWaalsContact O-OG1 3.14Å; N11-T14 WeakPolarHBondContact CA-OG1 3.36Å; N11-T14 PolarHBondContact O-OG1 3.41Å; T14-I16 VanDerWaalsContact C-N 3.34Å; T14-I16 PolarHBondContact O-N 3.48Å; T14-I17 PolarHBondContact O-N 2.99Å; T14-N18 PolarHBondContact O-N 2.98Å
15G68.3Low74Confident30 Ų30100.9 Ų100.931%0.30959%0.589SS.*Hα-helixtrans-69.5-25.2178.900000114.9N11 L12N11-G15 PolarHBondContact O-N 3.02Å; L12-G15 PolarHBondContact O-N 3.26Å
16I61.5Low72.3Confident117 Ų117100 Ų10060%0.659%0.594SS**Hα-helixtrans-76.3-40.1173.5-62.6-67.4000110.7L12 T14 N18 R19L12-I16 WeakPolarHBondContact O-CG1 3.42Å; L12-I16 PolarHBondContact O-N 3.36Å; T14-I16 VanDerWaalsContact C-N 3.34Å; T14-I16 PolarHBondContact O-N 3.48Å; I16-N18 PolarHBondContact O-N 3.28Å; I16-R19 PolarHBondContact O-N 3.43Å
17I59.4Low70.5Confident132 Ų132100.9 Ų100.968%0.67761%0.607SS**Hα-helixtrans-68.6-35-179.2-61.3165.7000111.3A13 T14 R19A13-I17 WeakPolarHBondContact O-CD1 3.44Å; A13-I17 WeakPolarHBondContact O-CG1 3.49Å; T14-I17 PolarHBondContact O-N 2.99Å; I17-R19 VanDerWaalsContact C-N 3.3Å; I17-R19 PolarHBondContact O-N 3.06Å
18N57.8Low68.9Low150 Ų150104.6 Ų104.680%0.80262%0.623SS**THydrogen-bonded Turntrans-80-4.7-178.9-163.156.5000114.5T14 I16T14-N18 PolarHBondContact O-N 2.98Å; I16-N18 PolarHBondContact O-N 3.28Å
19R55.8Low67.5Low198 Ų198111.8 Ų111.875%0.74764%0.643SS**THydrogen-bonded Turntrans-111.7-4.2-179-138.2-171.4-63.3170.7-0.7113.9I16 I17 S21I16-R19 PolarHBondContact O-N 3.43Å; I17-R19 VanDerWaalsContact C-N 3.3Å; I17-R19 PolarHBondContact O-N 3.06Å; R19-S21 PolarHBondContact O-N 3.47Å
20S56.9Low65.8Low96 Ų96112.2 Ų112.267%0.67165%0.651SS**  trans-76.861.1165.9-59.40000109.8A22S20-A22 PolarHBondContact O-N 3.42Å
21S58.8Low64.2Low108 Ų108115.2 Ų115.276%0.75567%0.666SS**  trans-59.7105.1160.341.50000106.5R19 S23R19-S21 PolarHBondContact O-N 3.47Å; S21-S23 PolarHBondContact O-N 3Å
22A58.3Low62.8Low90 Ų90117.2 Ų117.274%0.74468%0.675SS**  trans-8.196.6175.100000112.9S20 A24S20-A22 PolarHBondContact O-N 3.42Å; A22-A24 PolarHBondContact O-N 3.42Å
23S53.4Low61Low110 Ų110117 Ų11777%0.76968%0.683SS**  trans-65.889.9153.9-177.70000103.7S21 P25S21-S23 PolarHBondContact O-N 3Å; S23-P25 WeakPolarHBondContact O-CD 3.39Å
24A61.7Low59.5Low74 Ų74120.3 Ų120.361%0.61270%0.699SS**PPolyproline II helixtrans-47.8119.1163.900000104.5A22A22-A24 PolarHBondContact O-N 3.42Å
25P61.7Low58.5Low103 Ų103122.1 Ų122.167%0.66972%0.715SS**PPolyproline II helixtrans-52.9135.518020.5-30.5000106.5S23 T27S23-P25 WeakPolarHBondContact O-CD 3.39Å; P25-T27 PolarHBondContact O-N 3.01Å
26P59.1Low58.1Low104 Ų104123.2 Ų123.268%0.67573%0.726SS**PPolyproline II helixtrans-49.8121.8179.320.8-31.7000106.8L28P26-L28 PolarHBondContact O-N 2.97Å
27T57.8Low57.7Low126 Ų126123.4 Ų123.477%0.77374%0.735SS**  trans-61.992-176.9-42.20000106.9P25 R29P25-T27 PolarHBondContact O-N 3.01Å; T27-R29 PolarHBondContact O-N 3.48Å
28L60.8Low57.8Low153 Ų153123.6 Ų123.680%0.80174%0.742SS**  trans-65.996169-69.8178.6000104.4P26 P30P26-L28 PolarHBondContact O-N 2.97Å; L28-P30 WeakPolarHBondContact O-CD 3.43Å; L28-P30 VanDerWaalsContact O-N 3.1Å
29R63.5Low57.8Low215 Ų215126.7 Ų126.781%0.81174%0.743SS**  trans-59.3118175.3-52.5-126.1-154.4-158.37.8105.1T27 I31T27-R29 PolarHBondContact O-N 3.48Å; R29-I31 PolarHBondContact O-N 3.03Å
30P57.9Low57.5Low105 Ų105121.8 Ų121.868%0.68274%0.739SS**  trans-57.6116.8176.6-20.831.8000107.5L28 I32L28-P30 WeakPolarHBondContact O-CD 3.43Å; L28-P30 VanDerWaalsContact O-N 3.1Å; P30-I32 HydrophobicContact CB-CG1 4.26Å; P30-I32 PolarHBondContact O-N 3.38Å
31I57.3Low57.6Low177 Ų177123.5 Ų123.591%0.90875%0.746SS**  trans-78.552.3166-50.9170.7000106.5R29R29-I31 PolarHBondContact O-N 3.03Å
32I60.8Low57.2Low142 Ų142126.8 Ų126.873%0.72875%0.749SS**  trans-125.7107.1175.8-41.6178.6000105.4P30P30-I32 HydrophobicContact CB-CG1 4.26Å; P30-I32 PolarHBondContact O-N 3.38Å
33S49Very low57Low102 Ų102127.7 Ų127.771%0.71375%0.75SS**  trans-54166.4177.7-1340000112S35S33-S35 PolarHBondContact O-N 3.28Å
34P51.8Low56.8Low124 Ų124127.7 Ų127.781%0.80574%0.741SS**SBendtrans-69.210.8-132.732.2-40.4000118G36P34-G36 PolarHBondContact O-N 3.18Å
35S57.6Low56.8Low109 Ų109129.4 Ų129.476%0.76275%0.746SS**SBendtrans-89.292.3174.2-48.40000107.4S33S33-S35 PolarHBondContact O-N 3.28Å
36G58.8Low56.4Low53 Ų53132.1 Ų132.155%0.54675%0.75SS.*  trans-51.9171.4-164.100000117.4P34 T38P34-G36 PolarHBondContact O-N 3.18Å; G36-T38 PolarHBondContact O-N 3.35Å
37P53.7Low56.2Low121 Ų121131.8 Ų131.879%0.78676%0.756SS**  trans-56.9129.2179.922.7-31000110.5W39P37-W39 PolarHBondContact O-N 2.77Å
38T61.7Low55.7Low135 Ų135131.6 Ų131.683%0.82876%0.757SS**SBendtrans-68.48.8-178.843.80000114.4G36G36-T38 PolarHBondContact O-N 3.35Å
39W57.2Low55.5Low215 Ų215132.6 Ų132.681%0.81476%0.758SS**  trans-112.6124.8-173.8-6888.4000111.8P37P37-W39 PolarHBondContact O-N 2.77Å
40S50.1Low55.1Low95 Ų95128.8 Ų128.866%0.66475%0.753SS**  trans80.378.7154.6-55.70000116.1Q42S40-Q42 PolarHBondContact O-N 3.42Å
41T59Low54.9Low132 Ų132131.9 Ų131.981%0.8176%0.758SS**  19.891.1124.926.80000114.7S43T41-S43 PolarHBondContact O-N 3.4Å
42Q49.9Very low54.7Low178 Ų178128.9 Ų128.983%0.83275%0.753SS**  trans-59.799.9147.5-175.9175.3-73.800105.4S40 D44S40-Q42 PolarHBondContact O-N 3.42Å; Q42-D44 PolarHBondContact O-N 3.11Å; Q42-D44 VanDerWaalsContact O-N 3.12Å
43S53.4Low54.1Low108 Ų108127.5 Ų127.576%0.75576%0.756SS**  trans-56.4119.7162.1-85.80000106.1T41T41-S43 PolarHBondContact O-N 3.4Å
44D51.1Low54.3Low111 Ų111127.8 Ų127.859%0.59476%0.758SS**  trans-53.2130.3173.4-177-104.2000109.5Q42 Q46Q42-D44 PolarHBondContact O-N 3.11Å; Q42-D44 VanDerWaalsContact O-N 3.12Å; D44-Q46 PolarHBondContact O-N 3.49Å; D44-Q46 WeakPolarHBondContact OD1-CB 3.36Å; D44-Q46 PolarHBondContact OD1-N 2.97Å
45P60.5Low54.4Low109 Ų109128.1 Ų128.171%0.70876%0.76SS**SBendtrans-83.661.5173.835.7-32.1000109.1
46Q53.5Low53.8Low160 Ų160125.9 Ų125.975%0.74875%0.754SS**SBendtrans-160.1113.9165.8-112.4163.1-27.200111.8D44 P48D44-Q46 PolarHBondContact O-N 3.49Å; D44-Q46 WeakPolarHBondContact OD1-CB 3.36Å; D44-Q46 PolarHBondContact OD1-N 2.97Å; Q46-P48 WeakPolarHBondContact O-CD 3.48Å
47A55.4Low53.6Low97 Ų97129 Ų12980%0.80277%0.767SS**  trans-57.2133.6177.900000111.9
48P47.1Very low53.7Low123 Ų123127.4 Ų127.480%0.79976%0.759SS**  trans-97103.1151.32.518.9000107.7Q46Q46-P48 WeakPolarHBondContact O-CD 3.48Å
49E56.8Low52.4Low174 Ų174130.3 Ų130.381%0.81376%0.761SS**  trans-9.3134.5147.7-51.917594.700115.7
50N54.4Low52Low134 Ų134132 Ų13272%0.71778%0.783SS**  trans47.6123.5161.8-91.2-83.9000115.8
51H52.8Low52.1Low171 Ų171133.9 Ų133.979%0.79279%0.789SS**  -171.6121.878.2-82.8-84000107.3S53H51-S53 PolarHBondContact O-N 3.49Å
52S55.1Low51.7Low114 Ų114134 Ų13480%0.79779%0.788SS**  trans-55.3126.4160.1175.30000109.3
53S46.9Very low51.8Low113 Ų113131.6 Ų131.679%0.7979%0.786SS**  trans-16799.2148.7-78.50000109.2H51H51-S53 PolarHBondContact O-N 3.49Å
54S54.1Low51.7Low108 Ų108132.9 Ų132.976%0.75579%0.788SS**  trans-59.7133.4165.2175.90000109.7G56S54-G56 VanDerWaalsContact C-N 3.29Å; S54-G56 PolarHBondContact O-N 3.06Å
55P53.2Low51.7Low130 Ų130134.3 Ų134.384%0.84480%0.8SS**  trans-77.483.5171.430.6-29.6000109
56G44.2Very low51.2Low62 Ų62136 Ų13664%0.63981%0.806SS**  trans-105.997.4-178.900000112.7S54S54-G56 VanDerWaalsContact C-N 3.29Å; S54-G56 PolarHBondContact O-N 3.06Å
57S55.1Low51Low118 Ų118134.3 Ų134.383%0.82581%0.81SS**  trans49.9115.4143.9-156.70000119.8
58S55.4Low50.7Low88 Ų88137.2 Ų137.262%0.61581%0.811SS**  trans-57.4153.5164.255.70000115.5
59F35Very low51Low196 Ų196138.3 Ų138.386%0.8681%0.812SS**  trans72.3107.2161-62.5-80.2000119.2
60I48.5Very low50.4Low252 Ų252135.1 Ų135.1100%1.29281%0.812SS**  -162.40117.931.4174.9000110

Retrieved 60 of 60 residues in 39.6 ms (Link to these results)