A0A087WUU2_HUMAN Loading...

Ubiquitin specific peptidase 12

AlphaFold DB , UniProt , Accession A0A087WUU2, Species HUMAN (Homo sapiens, Human), Gene USP12, Length 18 aa.

						>A0A087WUU2_HUMAN|A0A087WUU2|USP12
MEILMTVSKFASICTMEW
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	70.3	Confident	87.2	Confident	186 Å²	186	120.4 Å²	120.4	92%	0.916	63%	0.631	S	S	*	*				0	-33.3	0	-167.9	157.3	168.8	0	112.3	M5	M1-M5 HydrophobicContact CG-CE 4Å; M1-M5 HydrophobicContact CE-CE 3.68Å
2	E	84.8	Confident	87.2	Confident	165 Å²	165	115.3 Å²	115.3	77%	0.771	61%	0.613	S	S	*	*	H	α-helix	trans	-67.8	-39.8	-178.2	-63.2	173.9	121.3	0	114.6	L4 M5 T6	E2-L4 PolarHBondContact O-N 3.38Å; E2-L4 VanDerWaalsContact C-N 3.33Å; E2-M5 PolarHBondContact O-N 3.03Å; E2-M5 VanDerWaalsContact O-N 3.16Å; E2-T6 PolarHBondContact O-N 3.16Å; E2-T6 VanDerWaalsContact O-N 3.13Å; E2-T6 PolarHBondContact O-OG1 2.91Å
3	I	87.4	Confident	87.2	Confident	140 Å²	140	114.2 Å²	114.2	72%	0.718	61%	0.605	S	S	*	*	H	α-helix	trans	-60.3	-43.4	179.8	-63.1	170.4	0	0	111.4	M5 T6 V7	I3-M5 VanDerWaalsContact C-N 3.3Å; I3-M5 PolarHBondContact O-N 3.01Å; I3-T6 PolarHBondContact O-N 3.2Å; I3-V7 HydrophobicContact CG2-CG2 4.43Å; I3-V7 WeakPolarHBondContact O-CG2 3.45Å; I3-V7 PolarHBondContact O-N 3.39Å
4	L	89.3	Confident	87	Confident	130 Å²	130	109.9 Å²	109.9	68%	0.681	59%	0.588	S	S	*	*	H	α-helix	trans	-60.5	-39.8	177.6	-101.2	119.9	0	0	112	E2 T6 V7 S8	E2-L4 PolarHBondContact O-N 3.38Å; E2-L4 VanDerWaalsContact C-N 3.33Å; L4-T6 VanDerWaalsContact C-N 3.34Å; L4-V7 PolarHBondContact O-N 3.26Å; L4-S8 PolarHBondContact O-N 3.38Å; L4-S8 PolarHBondContact O-OG 3.47Å
5	M	89.3	Confident	86.6	Confident	100 Å²	100	109.5 Å²	109.5	49%	0.493	59%	0.592	S	S	.	*	H	α-helix	trans	-66.2	-38.2	177.5	-67	-177.8	-179	0	111.9	M1 E2 I3 K9	M1-M5 HydrophobicContact CG-CE 4Å; M1-M5 HydrophobicContact CE-CE 3.68Å; E2-M5 PolarHBondContact O-N 3.03Å; E2-M5 VanDerWaalsContact O-N 3.16Å; I3-M5 VanDerWaalsContact C-N 3.3Å; I3-M5 PolarHBondContact O-N 3.01Å; M5-K9 WeakPolarHBondContact O-CB 3.39Å; M5-K9 VanDerWaalsContact O-CG 3.29Å; M5-K9 WeakPolarHBondContact O-CG 3.39Å; M5-K9 PolarHBondContact O-N 3.46Å
6	T	90.1	Very high	85.9	Confident	95 Å²	95	112.4 Å²	112.4	58%	0.583	60%	0.603	S	S	*	*	H	α-helix	trans	-65.7	-45	177.1	-56.4	0	0	0	111.5	E2 I3 L4 K9 F10	E2-T6 PolarHBondContact O-N 3.16Å; E2-T6 VanDerWaalsContact O-N 3.13Å; E2-T6 PolarHBondContact O-OG1 2.91Å; I3-T6 PolarHBondContact O-N 3.2Å; L4-T6 VanDerWaalsContact C-N 3.34Å; T6-K9 PolarHBondContact O-N 3.37Å; T6-F10 WeakPolarHBondContact O-CB 3.47Å; T6-F10 PolarHBondContact O-N 3.33Å
7	V	89.6	Confident	84.8	Confident	92 Å²	92	115.2 Å²	115.2	56%	0.558	61%	0.611	S	S	*	*	H	α-helix	trans	-62.9	-44.8	178.1	174.2	0	0	0	111	I3 L4 K9 F10 A11	I3-V7 HydrophobicContact CG2-CG2 4.43Å; I3-V7 WeakPolarHBondContact O-CG2 3.45Å; I3-V7 PolarHBondContact O-N 3.39Å; L4-V7 PolarHBondContact O-N 3.26Å; V7-K9 PolarHBondContact O-N 3.12Å; V7-F10 PolarHBondContact O-N 3.21Å; V7-A11 WeakPolarHBondContact O-CB 3.42Å; V7-A11 PolarHBondContact O-N 3.04Å
8	S	90.8	Very high	83.3	Confident	78 Å²	78	125.3 Å²	125.3	55%	0.545	64%	0.64	S	S	.	*	H	α-helix	trans	-63.4	-40.3	177.3	-68.8	0	0	0	112.9	L4 S12	L4-S8 PolarHBondContact O-N 3.38Å; L4-S8 PolarHBondContact O-OG 3.47Å; S8-S12 WeakPolarHBondContact O-CB 3.19Å; S8-S12 PolarHBondContact O-N 3.24Å
9	K	89.8	Confident	83.3	Confident	146 Å²	146	125.3 Å²	125.3	64%	0.635	64%	0.64	S	S	*	*	H	α-helix	trans	-63.8	-44.5	175.9	-76.4	175.3	-179.9	-178.6	111.6	M5 T6 V7 S12 I13	M5-K9 WeakPolarHBondContact O-CB 3.39Å; M5-K9 VanDerWaalsContact O-CG 3.29Å; M5-K9 WeakPolarHBondContact O-CG 3.39Å; M5-K9 PolarHBondContact O-N 3.46Å; T6-K9 PolarHBondContact O-N 3.37Å; V7-K9 PolarHBondContact O-N 3.12Å; K9-S12 PolarHBondContact O-N 3.1Å; K9-I13 WeakPolarHBondContact O-CG1 3.29Å; K9-I13 PolarHBondContact O-N 3.44Å
10	F	89.3	Confident	83.3	Confident	141 Å²	141	125.3 Å²	125.3	62%	0.618	64%	0.64	S	S	*	*	H	α-helix	trans	-64.4	-46.8	179.1	-172.6	-100.3	0	0	111.7	T6 V7 S12 I13 C14	T6-F10 WeakPolarHBondContact O-CB 3.47Å; T6-F10 PolarHBondContact O-N 3.33Å; V7-F10 PolarHBondContact O-N 3.21Å; F10-S12 VanDerWaalsContact C-N 3.31Å; F10-S12 PolarHBondContact O-N 2.97Å; F10-I13 PolarHBondContact O-N 3.35Å; F10-C14 PolarHBondContact O-N 3.13Å; F10-C14 VanDerWaalsContact O-N 3.12Å; F10-C14 PolarHBondContact O-SG 3.25Å; F10-C14 VanDerWaalsContact O-SG 3.37Å
11	A	88.3	Confident	83.3	Confident	51 Å²	51	125.3 Å²	125.3	42%	0.421	64%	0.64	S	S	.	*	H	α-helix	trans	-58.5	-43.2	176.6	0	0	0	0	112	V7 I13 C14 T15	V7-A11 WeakPolarHBondContact O-CB 3.42Å; V7-A11 PolarHBondContact O-N 3.04Å; A11-I13 VanDerWaalsContact C-N 3.32Å; A11-I13 PolarHBondContact O-N 3.02Å; A11-C14 PolarHBondContact O-N 2.92Å; A11-T15 PolarHBondContact O-N 3.09Å; A11-T15 VanDerWaalsContact O-N 3.09Å; A11-T15 PolarHBondContact O-OG1 3.41Å
12	S	87.2	Confident	84.1	Confident	60 Å²	60	121.7 Å²	121.7	42%	0.42	62%	0.624	S	S	.	*	H	α-helix	trans	-61.3	-38.3	178.4	-177.3	0	0	0	113	S8 K9 F10 T15 M16	S8-S12 WeakPolarHBondContact O-CB 3.19Å; S8-S12 PolarHBondContact O-N 3.24Å; K9-S12 PolarHBondContact O-N 3.1Å; F10-S12 VanDerWaalsContact C-N 3.31Å; F10-S12 PolarHBondContact O-N 2.97Å; S12-T15 WeakPolarHBondContact CA-OG1 3.33Å; S12-T15 PolarHBondContact O-OG1 3.18Å; S12-M16 WeakPolarHBondContact O-CG 3.38Å; S12-M16 PolarHBondContact O-N 3.41Å
13	I	87.3	Confident	84	Confident	100 Å²	100	119 Å²	119	51%	0.513	61%	0.614	S	S	.	*	H	α-helix	trans	-66.8	-48.8	177.9	-67.6	164.1	0	0	109.6	K9 F10 A11 T15 M16	K9-I13 WeakPolarHBondContact O-CG1 3.29Å; K9-I13 PolarHBondContact O-N 3.44Å; F10-I13 PolarHBondContact O-N 3.35Å; A11-I13 VanDerWaalsContact C-N 3.32Å; A11-I13 PolarHBondContact O-N 3.02Å; I13-T15 VanDerWaalsContact C-N 3.26Å; I13-T15 PolarHBondContact O-N 3.32Å; I13-M16 PolarHBondContact O-N 3.02Å; I13-M16 VanDerWaalsContact O-N 3.1Å
14	C	84.7	Confident	83.8	Confident	54 Å²	54	117.6 Å²	117.6	37%	0.365	61%	0.607	S	S	.	*	H	α-helix	trans	-62.4	-30.6	-179.1	-63.9	0	0	0	113.4	F10 A11	F10-C14 PolarHBondContact O-N 3.13Å; F10-C14 VanDerWaalsContact O-N 3.12Å; F10-C14 PolarHBondContact O-SG 3.25Å; F10-C14 VanDerWaalsContact O-SG 3.37Å; A11-C14 PolarHBondContact O-N 2.92Å
15	T	81.5	Confident	83.4	Confident	104 Å²	104	116.7 Å²	116.7	64%	0.638	60%	0.602	S	S	*	*	H	α-helix	trans	-79.4	-16	176.8	39.2	0	0	0	114.8	A11 S12 I13	A11-T15 PolarHBondContact O-N 3.09Å; A11-T15 VanDerWaalsContact O-N 3.09Å; A11-T15 PolarHBondContact O-OG1 3.41Å; S12-T15 WeakPolarHBondContact CA-OG1 3.33Å; S12-T15 PolarHBondContact O-OG1 3.18Å; I13-T15 VanDerWaalsContact C-N 3.26Å; I13-T15 PolarHBondContact O-N 3.32Å
16	M	75.1	Confident	83	Confident	157 Å²	157	118 Å²	118	77%	0.773	61%	0.611	S	S	*	*	H	α-helix	trans	-90.3	-12.3	178.8	-66.5	-107.6	-179.8	0	112.7	S12 I13	S12-M16 WeakPolarHBondContact O-CG 3.38Å; S12-M16 PolarHBondContact O-N 3.41Å; I13-M16 PolarHBondContact O-N 3.02Å; I13-M16 VanDerWaalsContact O-N 3.1Å
17	E	67.8	Low	82.4	Confident	160 Å²	160	119.9 Å²	119.9	75%	0.748	61%	0.613	S	S	*	*			trans	-94.4	11.1	179.4	-75.4	-172.2	97.9	0	114.2
18	W	57.2	Low	81.7	Confident	296 Å²	296	122.5 Å²	122.5	100%	1.121	62%	0.618	S	S	*	*			trans	-109.2	0	171.9	-78.4	86.4	0	0	112.5

Retrieved 18 of 18 residues in 21.2 ms (Link to these results)

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