A0A087WUU3_HUMAN Loading...

Zinc finger and BTB domain containing 8 opposite strand

AlphaFold DB , UniProt , Accession A0A087WUU3, Species HUMAN (Homo sapiens, Human), Gene ZBTB8OS, Length 49 aa.

>A0A087WUU3_HUMAN|A0A087WUU3|ZBTB8OS
MAQEEEDVRDYNLTEEQKAIKAKYPPVNRKYECEFGSYSRCPWIVLHRA
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M49.6Very low56.9Low242 Ų242137.7 Ų137.7100%1.19269%0.688SS**  0137.30-63-62.1-88.400107.1
2A47Very low59.4Low86 Ų86140.3 Ų140.371%0.71171%0.706SS**  trans80.380.9-173.700000116.2E4A2-E4 VanDerWaalsContact C-N 3.34Å
3Q46.8Very low61.6Low150 Ų150133.9 Ų133.970%0.70168%0.675SS**  trans-104.645.2149.6-72.6168.7-114.900108.2P26Q3-P26 HydrophobicContact CG-CB 4.24Å; Q3-P26 HydrophobicContact CG-CG 3.98Å
4E47.8Very low63.8Low173 Ų173129.9 Ų129.981%0.80866%0.66SS**  trans-100.5-2.4-170.1-73.1179.2149.200113.4A2 E6A2-E4 VanDerWaalsContact C-N 3.34Å; E4-E6 PolarHBondContact O-N 3.49Å
5E50.2Low65.6Low186 Ų186132.5 Ų132.587%0.86967%0.669SS**SBendtrans-80.583.4158.8-74.3178.5146.200106.4
6E50.4Low67.3Low142 Ų142133.3 Ų133.366%0.66467%0.67SS**  trans12.8119.2140.5-163.7168.1-167.300112E4 V8E4-E6 PolarHBondContact O-N 3.49Å; E6-V8 WeakPolarHBondContact O-CA 3.48Å; E6-V8 WeakPolarHBondContact O-CG2 3.43Å; E6-V8 PolarHBondContact O-N 3.07Å
7D55.6Low68.7Low51 Ų51130.8 Ų130.827%0.27366%0.655SS.*  trans-55.682.2167.8-175.9-145.1000107.6R9 K21 R29D7-R9 CarbonylContact O-C 3.32Å; D7-R9 VanDerWaalsContact O-C 3.32Å; D7-R9 PolarHBondContact O-N 3.34Å; D7-K21 IonicContact OD1-NZ 3.51Å; D7-K21 PolarHBondContact OD1-NZ 2.98Å; D7-K21 IonicContact OD2-NZ 2.64Å; D7-R29 IonicContact OD2-CZ 3.15Å; D7-R29 IonicContact OD2-NH1 2.72Å; D7-R29 PolarHBondContact OD2-NH1 3.35Å; D7-R29 IonicContact OD2-NH2 2.85Å; D7-R29 PolarHBondContact OD2-NH2 3.26Å
8V59.4Low69.7Low119 Ų119130.4 Ų130.472%0.72165%0.649SS**SBendtrans-58.7-5.2-159.9-174.30000112.9E6E6-V8 WeakPolarHBondContact O-CA 3.48Å; E6-V8 WeakPolarHBondContact O-CG2 3.43Å; E6-V8 PolarHBondContact O-N 3.07Å
9R68.4Low70.8Confident97 Ų97126.3 Ų126.337%0.36664%0.638SS.*SBendtrans-104.9101.3172.6-57.8-167.167.2-180-0.5108.4D7 Y11 F35D7-R9 CarbonylContact O-C 3.32Å; D7-R9 VanDerWaalsContact O-C 3.32Å; D7-R9 PolarHBondContact O-N 3.34Å; R9-Y11 VanDerWaalsContact C-N 3.28Å; R9-Y11 HydrophobicContact CB-CD2 3.95Å; R9-Y11 HydrophobicContact CB-CE2 3.46Å; R9-Y11 VanDerWaalsContact CB-CE2 3.46Å; R9-Y11 HydrophobicContact CG-CE2 4.48Å; R9-Y11 PolarHBondContact NE-OH 3.02Å; R9-Y11 PolarHBondContact NH1-OH 3.28Å; R9-Y11 VanDerWaalsContact NH1-OH 3.17Å; R9-Y11 PolarHBondContact NH2-OH 2.9Å; R9-Y11 WeakPolarHBondContact O-CD2 3.41Å; R9-Y11 PolarHBondContact O-N 3.49Å; R9-F35 VanDerWaalsContact NH2-CE2 3.32Å
10D69.1Low71.8Confident146 Ų146124.1 Ų124.178%0.78163%0.627SS**  trans-65.184.1173.9-72-51000111.3
11Y81.3Confident72.5Confident123 Ų123123 Ų12348%0.48262%0.618SS.*  trans-83.5132.3167-64.7-76000109.6R9 L13R9-Y11 VanDerWaalsContact C-N 3.28Å; R9-Y11 HydrophobicContact CB-CD2 3.95Å; R9-Y11 HydrophobicContact CB-CE2 3.46Å; R9-Y11 VanDerWaalsContact CB-CE2 3.46Å; R9-Y11 HydrophobicContact CG-CE2 4.48Å; R9-Y11 PolarHBondContact NE-OH 3.02Å; R9-Y11 PolarHBondContact NH1-OH 3.28Å; R9-Y11 VanDerWaalsContact NH1-OH 3.17Å; R9-Y11 PolarHBondContact NH2-OH 2.9Å; R9-Y11 WeakPolarHBondContact O-CD2 3.41Å; R9-Y11 PolarHBondContact O-N 3.49Å; Y11-L13 VanDerWaalsContact C-N 3.26Å; Y11-L13 PolarHBondContact O-N 3.19Å
12N87.6Confident74.3Confident169 Ų169115.6 Ų115.690%0.90460%0.595SS**  trans-71.880.5170.3-70.8-42.6000110.2
13L87.9Confident76.5Confident57 Ų57119 Ų11930%0.29859%0.594SS.*  trans-81.2139.9-179.8-62.5177.9000112.2Y11 Q17 K18 K21Y11-L13 VanDerWaalsContact C-N 3.26Å; Y11-L13 PolarHBondContact O-N 3.19Å; L13-Q17 HydrophobicContact CB-CB 4.27Å; L13-Q17 HydrophobicContact CD2-CB 4.31Å; L13-K18 HydrophobicContact CB-CG 4.09Å; L13-K18 WeakPolarHBondContact O-CE 3.32Å; L13-K21 HydrophobicContact CD1-CD 4.19Å
14T92.6Very high78.5Confident77 Ų77119.8 Ų119.847%0.47259%0.591SS.*  trans-74.1163.1171.266.20000111.8E16 Q17 K18T14-E16 VanDerWaalsContact C-N 3.28Å; T14-E16 PolarHBondContact O-N 3.24Å; T14-Q17 PolarHBondContact O-N 2.95Å; T14-Q17 VanDerWaalsContact O-N 3.15Å; T14-Q17 WeakPolarHBondContact OG1-CG 3.37Å; T14-Q17 PolarHBondContact OG1-OE1 3.47Å; T14-K18 WeakPolarHBondContact O-CG 3.47Å; T14-K18 PolarHBondContact O-N 3.37Å
15E90.7Very high80.3Confident170 Ų170116.7 Ų116.779%0.79459%0.586SS**Hα-helixtrans-59.1-38.6-179.7-64.7-169.6130.900112.7K18 A19E15-K18 PolarHBondContact O-N 3.31Å; E15-A19 PolarHBondContact O-N 3.15Å
16E93.1Very high81.9Confident145 Ų145111.5 Ų111.568%0.67857%0.569SS**Hα-helixtrans-64.8-40.7176.5-170.3178.9179.800111.9T14 A19 I20T14-E16 VanDerWaalsContact C-N 3.28Å; T14-E16 PolarHBondContact O-N 3.24Å; E16-A19 WeakPolarHBondContact O-CB 3.47Å; E16-A19 PolarHBondContact O-N 3.33Å; E16-I20 HydrophobicContact CG-CD1 4.26Å; E16-I20 VanDerWaalsContact O-CG1 3.32Å; E16-I20 WeakPolarHBondContact O-CG1 3.32Å; E16-I20 PolarHBondContact O-N 2.85Å
17Q89.9Confident83.5Confident91 Ų91110.2 Ų110.243%0.42557%0.57SS.*Hα-helixtrans-66.8-37.3176.7-70.4171.3-16.400111.9L13 T14 I20 K21L13-Q17 HydrophobicContact CB-CB 4.27Å; L13-Q17 HydrophobicContact CD2-CB 4.31Å; T14-Q17 PolarHBondContact O-N 2.95Å; T14-Q17 VanDerWaalsContact O-N 3.15Å; T14-Q17 WeakPolarHBondContact OG1-CG 3.37Å; T14-Q17 PolarHBondContact OG1-OE1 3.47Å; Q17-I20 PolarHBondContact O-N 2.72Å; Q17-K21 WeakPolarHBondContact O-CB 2.96Å; Q17-K21 PolarHBondContact O-N 3Å
18K87.7Confident84.8Confident123 Ų123113.8 Ų113.854%0.53559%0.589SS.*Hα-helixtrans-63-43.1172.3-68.3177.3-176.5-179.50111L13 T14 E15 I20 K21 A22L13-K18 HydrophobicContact CB-CG 4.09Å; L13-K18 WeakPolarHBondContact O-CE 3.32Å; T14-K18 WeakPolarHBondContact O-CG 3.47Å; T14-K18 PolarHBondContact O-N 3.37Å; E15-K18 PolarHBondContact O-N 3.31Å; K18-I20 VanDerWaalsContact C-N 3.34Å; K18-I20 PolarHBondContact O-N 2.92Å; K18-K21 PolarHBondContact O-N 3.49Å; K18-A22 PolarHBondContact O-N 2.59Å
19A90.6Very high85.5Confident53 Ų53113.6 Ų113.644%0.43858%0.575SS.*Hα-helixtrans-63.3-39.2176.500000112.1E15 E16 A22 K23E15-A19 PolarHBondContact O-N 3.15Å; E16-A19 WeakPolarHBondContact O-CB 3.47Å; E16-A19 PolarHBondContact O-N 3.33Å; A19-A22 PolarHBondContact O-N 3.33Å; A19-K23 WeakPolarHBondContact O-CG 3.17Å; A19-K23 PolarHBondContact O-N 2.69Å
20I90.3Very high86.1Confident82 Ų82117.7 Ų117.742%0.42160%0.596SS.*Hα-helixtrans-67.1-45175-67.3164.4000110.9E16 Q17 K18 A22 K23 Y24E16-I20 HydrophobicContact CG-CD1 4.26Å; E16-I20 VanDerWaalsContact O-CG1 3.32Å; E16-I20 WeakPolarHBondContact O-CG1 3.32Å; E16-I20 PolarHBondContact O-N 2.85Å; Q17-I20 PolarHBondContact O-N 2.72Å; K18-I20 VanDerWaalsContact C-N 3.34Å; K18-I20 PolarHBondContact O-N 2.92Å; I20-A22 PolarHBondContact O-N 2.64Å; I20-K23 WeakPolarHBondContact O-CB 3.44Å; I20-K23 PolarHBondContact O-N 2.85Å; I20-K23 VanDerWaalsContact O-N 3.07Å; I20-Y24 HydrophobicContact CG2-CD2 4.49Å; I20-Y24 HydrophobicContact CG2-CE2 4.32Å; I20-Y24 WeakPolarHBondContact O-CD2 3.45Å
21K86.6Confident86.5Confident102 Ų102118.8 Ų118.844%0.44359%0.59SS.*Hα-helixtrans-60.1-33.3178.4-170.4177.2177.5-1710112.1D7 L13 Q17 K18D7-K21 IonicContact OD1-NZ 3.51Å; D7-K21 PolarHBondContact OD1-NZ 2.98Å; D7-K21 IonicContact OD2-NZ 2.64Å; L13-K21 HydrophobicContact CD1-CD 4.19Å; Q17-K21 WeakPolarHBondContact O-CB 2.96Å; Q17-K21 PolarHBondContact O-N 3Å; K18-K21 PolarHBondContact O-N 3.49Å
22A87.8Confident86.2Confident85 Ų85121.9 Ų121.970%0.70261%0.609SS**Hα-helixtrans-75.5-21.6176.500000114.4K18 A19 I20 Y24K18-A22 PolarHBondContact O-N 2.59Å; A19-A22 PolarHBondContact O-N 3.33Å; I20-A22 PolarHBondContact O-N 2.64Å; A22-Y24 VanDerWaalsContact C-N 3.3Å; A22-Y24 PolarHBondContact O-N 2.82Å
23K93.8Very high85.2Confident159 Ų159117 Ų11769%0.69159%0.588SS**Hα-helixtrans-72.8-22.4179.2-75.8174.6-176.2-178.70113.4A19 I20A19-K23 WeakPolarHBondContact O-CG 3.17Å; A19-K23 PolarHBondContact O-N 2.69Å; I20-K23 WeakPolarHBondContact O-CB 3.44Å; I20-K23 PolarHBondContact O-N 2.85Å; I20-K23 VanDerWaalsContact O-N 3.07Å
24Y87.9Confident84.6Confident166 Ų166122.5 Ų122.565%0.65161%0.612SS**SBendtrans-115150.4-173.2-65.6-74.5000111.5I20 A22I20-Y24 HydrophobicContact CG2-CD2 4.49Å; I20-Y24 HydrophobicContact CG2-CE2 4.32Å; I20-Y24 WeakPolarHBondContact O-CD2 3.45Å; A22-Y24 VanDerWaalsContact C-N 3.3Å; A22-Y24 PolarHBondContact O-N 2.82Å
25P85.9Confident82.6Confident108 Ų108125.2 Ų125.270%0.70162%0.617SS**PPolyproline II helixtrans-59.6147.8174.925.3-33.6000110.6
26P83.7Confident80.8Confident77 Ų77120.4 Ų120.450%0.561%0.613SS.*PPolyproline II helixtrans-59142.2175.930.9-42.6000112Q3Q3-P26 HydrophobicContact CG-CB 4.24Å; Q3-P26 HydrophobicContact CG-CG 3.98Å
27V84.3Confident78.6Confident114 Ų114116 Ų11669%0.69160%0.599SS**PPolyproline II helixtrans-85.9122.7172.2-1800000108.6R29V27-R29 PolarHBondContact O-N 3.17Å
28N81.4Confident76.7Confident126 Ų126119.6 Ų119.667%0.67461%0.609SS**  trans-71.1106.1169.6-175.2-1.8000109.3
29R75.2Confident75Confident115 Ų115118.6 Ų118.643%0.43462%0.618SS.*  trans-89.9109.4179.3-62.2-178.4-175.8157.57.4109.1D7 V27 Y31D7-R29 IonicContact OD2-CZ 3.15Å; D7-R29 IonicContact OD2-NH1 2.72Å; D7-R29 PolarHBondContact OD2-NH1 3.35Å; D7-R29 IonicContact OD2-NH2 2.85Å; D7-R29 PolarHBondContact OD2-NH2 3.26Å; V27-R29 PolarHBondContact O-N 3.17Å; R29-Y31 HydrophobicContact CB-CE1 4.36Å; R29-Y31 HydrophobicContact CG-CE1 4.5Å
30K81.1Confident73.3Confident184 Ų184126 Ų12680%0.863%0.634SS**  trans-100.718.1178.2-63.3-176.4177.3-1780113.7
31Y77Confident71.4Confident169 Ų169124.5 Ų124.566%0.66363%0.63SS**  trans-129.4136.6-177.459-89.4000108.8R29R29-Y31 HydrophobicContact CB-CE1 4.36Å; R29-Y31 HydrophobicContact CG-CE1 4.5Å
32E75.4Confident69.9Low187 Ų187124.8 Ų124.887%0.87464%0.643SS**  trans-93.3150.4171.8-69.8177.9-168.200109.3
33C66.6Low68Low67 Ų67131 Ų13145%0.45365%0.648SS.*  trans-95.9111.6173.8-148.50000108.6F35C33-F35 HydrophobicContact CB-CD2 3.74Å; C33-F35 HydrophobicContact CB-CE2 4.13Å; C33-F35 PolarHBondContact O-N 2.79Å; C33-F35 WeakPolarHBondContact SG-CD2 3.03Å; C33-F35 WeakPolarHBondContact SG-CE2 3.15Å
34E74.8Confident66.1Low172 Ų172128.2 Ų128.280%0.80464%0.64SS**  trans-73.460.9176.3-61.1-177.9-175.600110.9G36E34-G36 VanDerWaalsContact C-N 3.26Å; E34-G36 PolarHBondContact O-N 2.92Å
35F51.2Low64.6Low135 Ų135125.2 Ų125.259%0.59264%0.638SS**THydrogen-bonded Turntrans-78.777.9176.6-89.7-68000110.6R9 C33 Y38R9-F35 VanDerWaalsContact NH2-CE2 3.32Å; C33-F35 HydrophobicContact CB-CD2 3.74Å; C33-F35 HydrophobicContact CB-CE2 4.13Å; C33-F35 PolarHBondContact O-N 2.79Å; C33-F35 WeakPolarHBondContact SG-CD2 3.03Å; C33-F35 WeakPolarHBondContact SG-CE2 3.15Å; F35-Y38 HydrophobicContact CD1-CE2 4.43Å; F35-Y38 HydrophobicContact CE1-CE2 4.29Å
36G51.6Low63.1Low68 Ų68126.6 Ų126.670%0.70164%0.639SS**THydrogen-bonded Turntrans-152.2-12.4170.200000114.1E34 Y38E34-G36 VanDerWaalsContact C-N 3.26Å; E34-G36 PolarHBondContact O-N 2.92Å; G36-Y38 PolarHBondContact O-N 3.08Å
37S48.1Very low61.7Low54 Ų54130.6 Ų130.638%0.37865%0.651SS.*  trans-99.644.9177.874.70000112.9S39 R40S37-S39 PolarHBondContact O-N 2.92Å; S37-S39 VanDerWaalsContact O-N 3.08Å; S37-R40 PolarHBondContact O-N 3.09Å
38Y49.5Very low60Low166 Ų166136.3 Ų136.365%0.65166%0.66SS**G310 helixtrans-59.1-14.7162.7-113.5-89.2000111.7F35 G36 R40 I44F35-Y38 HydrophobicContact CD1-CE2 4.43Å; F35-Y38 HydrophobicContact CE1-CE2 4.29Å; G36-Y38 PolarHBondContact O-N 3.08Å; Y38-R40 VanDerWaalsContact C-N 3.27Å; Y38-R40 PolarHBondContact O-N 3.39Å; Y38-I44 HydrophobicContact CD1-CD1 4.2Å; Y38-I44 HydrophobicContact CE1-CD1 4.4Å
39S52.7Low58.3Low101 Ų101137.9 Ų137.971%0.70669%0.691SS**G310 helixtrans-74.4-5.3169.845.90000114.9S37S37-S39 PolarHBondContact O-N 2.92Å; S37-S39 VanDerWaalsContact O-N 3.08Å
40R53.9Low57.4Low209 Ų209139 Ų13979%0.78970%0.703SS**G310 helixtrans-120.218.7-177.7-143.6173.5-81.1174.3-5.1113.2S37 Y38 P42S37-R40 PolarHBondContact O-N 3.09Å; Y38-R40 VanDerWaalsContact C-N 3.27Å; Y38-R40 PolarHBondContact O-N 3.39Å; R40-P42 VanDerWaalsContact O-CD 3.26Å; R40-P42 WeakPolarHBondContact O-CD 3.26Å
41C50.4Low56.2Low50 Ų50136.6 Ų136.634%0.33870%0.698SS.*  trans-78.4107.8164.5-71.50000108.9W43 I44C41-W43 PolarHBondContact O-N 3.47Å; C41-W43 VanDerWaalsContact O-N 3.09Å; C41-I44 HydrophobicContact CB-CB 4.5Å; C41-I44 HydrophobicContact CB-CD1 3.95Å; C41-I44 HydrophobicContact CB-CG1 4.44Å; C41-I44 PolarHBondContact O-N 3.44Å
42P55.2Low55Low109 Ų109134.8 Ų134.871%0.70870%0.7SS**Hα-helixtrans-59.7-28-177.3-20.232.7000112.6R40 I44 V45 L46R40-P42 VanDerWaalsContact O-CD 3.26Å; R40-P42 WeakPolarHBondContact O-CD 3.26Å; P42-I44 PolarHBondContact O-N 3.47Å; P42-V45 PolarHBondContact O-N 3.17Å; P42-L46 PolarHBondContact O-N 3.47Å
43W47.6Very low53.8Low214 Ų214131.8 Ų131.881%0.81169%0.69SS**Hα-helixtrans-66.1-30.4-179.2-11857.5000114.5C41C41-W43 PolarHBondContact O-N 3.47Å; C41-W43 VanDerWaalsContact O-N 3.09Å
44I55.1Low53Low102 Ų102135.8 Ų135.852%0.52371%0.705SS.*Hα-helixtrans-80-27.6179.8-76.3160.1000111.4Y38 C41 P42Y38-I44 HydrophobicContact CD1-CD1 4.2Å; Y38-I44 HydrophobicContact CE1-CD1 4.4Å; C41-I44 HydrophobicContact CB-CB 4.5Å; C41-I44 HydrophobicContact CB-CD1 3.95Å; C41-I44 HydrophobicContact CB-CG1 4.44Å; C41-I44 PolarHBondContact O-N 3.44Å; P42-I44 PolarHBondContact O-N 3.47Å
45V55.3Low51.6Low102 Ų102133.4 Ų133.462%0.61870%0.698SS**Hα-helixtrans-79-26.2-178.2-160.50000111.8P42 H47P42-V45 PolarHBondContact O-N 3.17Å; V45-H47 PolarHBondContact O-N 3.5Å
46L54.4Low51.6Low137 Ų137133.3 Ų133.372%0.71771%0.706SS**THydrogen-bonded Turntrans-77.2-20.2-172.7-156.772.9000114.8P42P42-L46 PolarHBondContact O-N 3.47Å
47H54.3Low51.6Low161 Ų161138.3 Ų138.375%0.74571%0.706SS**THydrogen-bonded Turntrans-98.511-177.1-82.2-69.6000114.6V45V45-H47 PolarHBondContact O-N 3.5Å
48R49.8Very low51.9Low234 Ų234145.3 Ų145.388%0.88373%0.734SS**  trans-121.720-177.5-146.1169.7163-176.6-6.4113.1
49A44.4Very low52.1Low159 Ų159143.5 Ų143.5100%1.31474%0.741SS**  trans-100.40170.100000110.5

Retrieved 49 of 49 residues in 48.7 ms (Link to these results)