A0A087WVR6_HUMAN Loading...

Acetyl-CoA carboxylase alpha

AlphaFold DB , UniProt , Accession A0A087WVR6, Species HUMAN (Homo sapiens, Human), Gene ACACA, Length 42 aa.

						>A0A087WVR6_HUMAN|A0A087WVR6|ACACA
MSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEK
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.9	Very low	54.8	Low	242 Å²	242	153.7 Å²	153.7	100%	1.192	81%	0.807	S	S	*	*				0	121.1	0	-72.5	-86.7	-99.2	0	0	107.4
2	S	51.7	Low	54.7	Low	125 Å²	125	150.4 Å²	150.4	87%	0.874	79%	0.791	S	S	*	*			trans	-49.6	153.9	-174.2	44.4	0	0	0	0	115
3	G	52.8	Low	54.5	Low	55 Å²	55	157.4 Å²	157.4	57%	0.567	80%	0.8	S	S	*	*			cis	-168.3	150.1	20.6	0	0	0	0	0	114.4	H5	G3-H5 VanDerWaalsContact O-N 3.1Å; G3-H5 PolarHBondContact O-N 3.1Å
4	L	60.5	Low	54.7	Low	152 Å²	152	156.9 Å²	156.9	80%	0.796	79%	0.79	S	S	*	*			trans	-40.2	111.2	151.6	-88.4	84.7	0	0	0	109.9	V7	L4-V7 HydrophobicContact CD2-CG2 4.22Å
5	H	59.8	Low	54.9	Low	172 Å²	172	159.1 Å²	159.1	80%	0.796	79%	0.792	S	S	*	*			trans	-114.5	101.7	153.1	-82.9	96.7	0	0	0	107.8	G3	G3-H5 VanDerWaalsContact O-N 3.1Å; G3-H5 PolarHBondContact O-N 3.1Å
6	L	59.4	Low	55.2	Low	150 Å²	150	157.4 Å²	157.4	79%	0.785	79%	0.785	S	S	*	*			trans	81.6	61.2	155	-47.5	176.7	0	0	0	116.4	K8	L6-K8 PolarHBondContact O-N 3.28Å
7	V	55.1	Low	55.6	Low	104 Å²	104	154.2 Å²	154.2	63%	0.63	77%	0.771	S	S	*	*	S	Bend		-41	121.7	125.3	161	0	0	0	0	108.5	L4	L4-V7 HydrophobicContact CD2-CG2 4.22Å
8	K	57.7	Low	56.1	Low	188 Å²	188	152.8 Å²	152.8	82%	0.817	78%	0.778	S	S	*	*			trans	103.1	58.9	170.8	-56	161.7	-173.9	-177.8	0	117.4	L6 G10	L6-K8 PolarHBondContact O-N 3.28Å; K8-G10 VanDerWaalsContact C-N 3.3Å
9	Q	54.8	Low	57	Low	199 Å²	199	152.3 Å²	152.3	93%	0.93	77%	0.772	S	S	*	*			trans	-102.5	56.4	133.2	-149.9	-179.6	43.2	0	0	106.8
10	G	53.4	Low	58	Low	53 Å²	53	154.4 Å²	154.4	55%	0.546	77%	0.77	S	S	.	*				68.6	66.4	94.2	0	0	0	0	0	109.3	K8 D12	K8-G10 VanDerWaalsContact C-N 3.3Å; G10-D12 PolarHBondContact O-N 2.81Å
11	R	57.5	Low	59.3	Low	251 Å²	251	153.1 Å²	153.1	95%	0.947	77%	0.767	S	S	*	*	S	Bend	trans	15.2	53.5	154.2	-55.4	-178.3	-152.9	136.4	3.1	118
12	D	53.4	Low	61.4	Low	114 Å²	114	147.4 Å²	147.4	61%	0.61	74%	0.735	S	S	*	*			trans	-130.1	42.5	168.6	-128.7	1.5	0	0	0	109.1	G10 K14	G10-D12 PolarHBondContact O-N 2.81Å; D12-K14 HydrophobicContact CB-CG 4.5Å; D12-K14 PolarHBondContact O-N 2.68Å; D12-K14 WeakPolarHBondContact OD1-CE 3.21Å; D12-K14 WeakPolarHBondContact OD1-CG 3.48Å; D12-K14 WeakPolarHBondContact OD2-CE 2.97Å
13	R	52.8	Low	63.3	Low	241 Å²	241	147.2 Å²	147.2	91%	0.909	73%	0.729	S	S	*	*			trans	-61.7	70.2	133.4	-60	176.5	81.6	-171.8	6.5	105.2	K15	R13-K15 VanDerWaalsContact C-N 3.27Å; R13-K15 PolarHBondContact O-N 2.72Å
14	K	56.4	Low	65.3	Low	150 Å²	150	147.1 Å²	147.1	65%	0.652	72%	0.717	S	S	*	*			trans	-45.5	111.6	159	-70.2	-173.7	-179.8	178.2	0	101.9	D12 I16	D12-K14 HydrophobicContact CB-CG 4.5Å; D12-K14 PolarHBondContact O-N 2.68Å; D12-K14 WeakPolarHBondContact OD1-CE 3.21Å; D12-K14 WeakPolarHBondContact OD1-CG 3.48Å; D12-K14 WeakPolarHBondContact OD2-CE 2.97Å; K14-I16 VanDerWaalsContact C-N 3.26Å; K14-I16 PolarHBondContact O-N 2.82Å
15	K	59	Low	66.9	Low	190 Å²	190	144.2 Å²	144.2	83%	0.826	72%	0.715	S	S	*	*			trans	-38.6	106.9	169.5	-66	170.7	176.1	179	0	103.3	R13 D17	R13-K15 VanDerWaalsContact C-N 3.27Å; R13-K15 PolarHBondContact O-N 2.72Å; K15-D17 PolarHBondContact O-N 3.46Å; K15-D17 WeakPolarHBondContact O-CA 3.47Å
16	I	59.7	Low	68.6	Low	133 Å²	133	138.1 Å²	138.1	68%	0.682	69%	0.692	S	S	*	*			trans	-61.5	103.8	175.9	-70.8	171.6	0	0	0	100.3	K14 S18	K14-I16 VanDerWaalsContact C-N 3.26Å; K14-I16 PolarHBondContact O-N 2.82Å; I16-S18 WeakPolarHBondContact O-CA 3.47Å; I16-S18 PolarHBondContact O-N 2.72Å
17	D	61.8	Low	70.3	Confident	102 Å²	102	135 Å²	135	55%	0.545	68%	0.68	S	S	.	*			trans	-44.8	105.4	-164.2	-175.4	18.3	0	0	0	107.7	K15 Q19 R20	K15-D17 PolarHBondContact O-N 3.46Å; K15-D17 WeakPolarHBondContact O-CA 3.47Å; D17-Q19 PolarHBondContact O-N 2.9Å; D17-R20 HydrophobicContact CB-CG 4.23Å; D17-R20 PolarHBondContact O-N 2.83Å
18	S	65	Low	72.3	Confident	129 Å²	129	132.4 Å²	132.4	90%	0.902	67%	0.67	S	S	*	*	S	Bend	trans	-61.9	-10.8	-167.1	-58.4	0	0	0	0	111.5	I16	I16-S18 WeakPolarHBondContact O-CA 3.47Å; I16-S18 PolarHBondContact O-N 2.72Å
19	Q	72.6	Confident	74.1	Confident	143 Å²	143	127.9 Å²	127.9	67%	0.668	65%	0.652	S	S	*	*	S	Bend	trans	-137.8	86.3	173.7	-176.8	178.7	-27.7	0	0	108.1	D17 D21	D17-Q19 PolarHBondContact O-N 2.9Å; Q19-D21 PolarHBondContact O-N 2.9Å
20	R	77.4	Confident	76.1	Confident	194 Å²	194	123.2 Å²	123.2	73%	0.732	63%	0.629	S	S	*	*			trans	-71.5	117	165.4	-71.3	-171	-116.9	-155.2	0.1	107.7	D17 F22	D17-R20 HydrophobicContact CB-CG 4.23Å; D17-R20 PolarHBondContact O-N 2.83Å; R20-F22 PolarHBondContact O-N 3.17Å
21	D	85.3	Confident	78.1	Confident	129 Å²	129	121.7 Å²	121.7	69%	0.69	61%	0.609	S	S	*	*			trans	-56.2	129.4	170.4	-69.5	-30.4	0	0	0	109.2	Q19	Q19-D21 PolarHBondContact O-N 2.9Å
22	F	83.8	Confident	80	Confident	121 Å²	121	115.3 Å²	115.3	53%	0.531	60%	0.598	S	S	.	*			trans	-98.7	111.8	173.3	-178.2	-85.2	0	0	0	108.3	R20 V24 F34	R20-F22 PolarHBondContact O-N 3.17Å; F22-V24 HydrophobicContact CE1-CG1 3.52Å; F22-V24 HydrophobicContact CZ-CG1 3.69Å; F22-F34 HydrophobicContact CD1-CE2 4.25Å; F22-F34 HydrophobicContact CZ-CZ 3.81Å; F22-F34 AromaticContact CZ-CZ 3.81Å; F22-F34 HydrophobicContact CZ-CE2 3.62Å; F22-F34 AromaticContact CZ-CE2 3.62Å; F22-F34 AromaticContact CE1-CZ 3.52Å; F22-F34 HydrophobicContact CE1-CE2 3.34Å; F22-F34 AromaticContact CE1-CE2 3.34Å; F22-F34 HydrophobicContact CD1-CZ 4.04Å; F22-F34 HydrophobicContact CE1-CZ 3.52Å
23	T	91.2	Very high	81.9	Confident	122 Å²	122	118.8 Å²	118.8	75%	0.748	60%	0.602	S	S	*	*			trans	-123.8	151.7	176.8	58.3	0	0	0	0	110
24	V	94.5	Very high	84	Confident	53 Å²	53	113 Å²	113	32%	0.321	58%	0.584	S	S	.	*			trans	-133.1	151.6	176	-71.1	0	0	0	0	108.7	F22 S26 E29 F30	F22-V24 HydrophobicContact CE1-CG1 3.52Å; F22-V24 HydrophobicContact CZ-CG1 3.69Å; V24-S26 VanDerWaalsContact C-N 3.35Å; V24-E29 HydrophobicContact CB-CB 4.32Å; V24-F30 HydrophobicContact CG2-CB 3.99Å; V24-F30 HydrophobicContact CG2-CD2 4.21Å
25	A	93.9	Very high	85.8	Confident	90 Å²	90	109.2 Å²	109.2	74%	0.744	59%	0.587	S	S	*	*	S	Bend	trans	-79.6	-18.1	-172.5	0	0	0	0	0	113.2	E29	A25-E29 WeakPolarHBondContact CB-OE2 3.34Å; A25-E29 PolarHBondContact N-OE2 3.3Å; A25-E29 VanDerWaalsContact CB-OE2 3.27Å
26	S	95.6	Very high	87.5	Confident	45 Å²	45	102.2 Å²	102.2	32%	0.315	57%	0.569	S	S	.	*	S	Bend	trans	-158.1	164.1	-179.6	71.1	0	0	0	0	113.5	V24 A28 E29 F30	V24-S26 VanDerWaalsContact C-N 3.35Å; S26-A28 VanDerWaalsContact C-N 3.27Å; S26-A28 PolarHBondContact O-N 3.31Å; S26-A28 PolarHBondContact OG-N 3.29Å; S26-E29 PolarHBondContact O-N 3.28Å; S26-E29 PolarHBondContact OG-N 3.44Å; S26-F30 PolarHBondContact O-N 2.9Å; S26-F30 VanDerWaalsContact O-N 3.13Å
27	P	95.6	Very high	89.3	Confident	83 Å²	83	103.7 Å²	103.7	54%	0.539	58%	0.578	S	S	.	*	H	α-helix	trans	-58.8	-33.8	170.7	-26.9	36.9	0	0	0	113.9	F30 V31 V39	P27-F30 WeakPolarHBondContact O-CB 3.27Å; P27-F30 PolarHBondContact O-N 2.92Å; P27-V31 WeakPolarHBondContact O-CG2 3.3Å; P27-V31 PolarHBondContact O-N 3.36Å; P27-V39 HydrophobicContact CB-CG1 3.69Å
28	A	96.2	Very high	90.9	Very high	50 Å²	50	106.3 Å²	106.3	41%	0.413	59%	0.585	S	S	.	*	H	α-helix	trans	-66.8	-40	178	0	0	0	0	0	112.3	S26 F30 V31 T32 V39	S26-A28 VanDerWaalsContact C-N 3.27Å; S26-A28 PolarHBondContact O-N 3.31Å; S26-A28 PolarHBondContact OG-N 3.29Å; A28-F30 VanDerWaalsContact C-N 3.35Å; A28-V31 PolarHBondContact O-N 3.13Å; A28-T32 PolarHBondContact O-N 2.88Å; A28-T32 PolarHBondContact O-OG1 3.41Å; A28-V39 HydrophobicContact CB-CG2 4.06Å
29	E	95.9	Very high	92.4	Very high	94 Å²	94	102.9 Å²	102.9	44%	0.439	56%	0.558	S	S	.	*	H	α-helix	trans	-65.7	-38.6	173.6	-75.3	-169.8	162.7	0	0	112.1	V24 A25 S26 T32 R33	V24-E29 HydrophobicContact CB-CB 4.32Å; A25-E29 WeakPolarHBondContact CB-OE2 3.34Å; A25-E29 PolarHBondContact N-OE2 3.3Å; A25-E29 VanDerWaalsContact CB-OE2 3.27Å; S26-E29 PolarHBondContact O-N 3.28Å; S26-E29 PolarHBondContact OG-N 3.44Å; E29-T32 PolarHBondContact O-N 3.23Å; E29-R33 WeakPolarHBondContact O-CB 3.36Å; E29-R33 WeakPolarHBondContact O-CG 3.3Å; E29-R33 PolarHBondContact O-N 3.07Å
30	F	96.4	Very high	93.4	Very high	101 Å²	101	103.1 Å²	103.1	44%	0.443	56%	0.563	S	S	.	*	H	α-helix	trans	-55.5	-54	173.3	-175.9	-92.8	0	0	0	110.6	V24 S26 P27 A28 T32 R33 F34	V24-F30 HydrophobicContact CG2-CB 3.99Å; V24-F30 HydrophobicContact CG2-CD2 4.21Å; S26-F30 PolarHBondContact O-N 2.9Å; S26-F30 VanDerWaalsContact O-N 3.13Å; P27-F30 WeakPolarHBondContact O-CB 3.27Å; P27-F30 PolarHBondContact O-N 2.92Å; A28-F30 VanDerWaalsContact C-N 3.35Å; F30-T32 VanDerWaalsContact C-N 3.27Å; F30-T32 PolarHBondContact O-N 3.08Å; F30-R33 PolarHBondContact O-N 3.33Å; F30-F34 PolarHBondContact O-N 3.48Å; F30-F34 WeakPolarHBondContact O-CD2 3.42Å; F30-F34 VanDerWaalsContact O-CD2 3.3Å; F30-F34 HydrophobicContact CZ-CG 4.14Å; F30-F34 HydrophobicContact CZ-CE2 4.08Å; F30-F34 HydrophobicContact CZ-CD2 3.81Å; F30-F34 AromaticContact CZ-CD2 3.81Å; F30-F34 HydrophobicContact CG-CE2 4.39Å; F30-F34 HydrophobicContact CE2-CD2 3.51Å; F30-F34 HydrophobicContact CG-CD2 4.03Å; F30-F34 HydrophobicContact CE2-CZ 4.03Å; F30-F34 HydrophobicContact CE2-CE2 3.38Å; F30-F34 AromaticContact CE2-CE2 3.38Å; F30-F34 AromaticContact CE2-CD2 3.51Å; F30-F34 HydrophobicContact CE1-CG 4.46Å; F30-F34 HydrophobicContact CE1-CD2 4.2Å; F30-F34 HydrophobicContact CD2-CE2 3.57Å; F30-F34 AromaticContact CD2-CE2 3.57Å; F30-F34 HydrophobicContact CD2-CD2 3.63Å; F30-F34 AromaticContact CD2-CD2 3.63Å; F30-F34 HydrophobicContact CD1-CD2 4.3Å; F30-F34 HydrophobicContact CE2-CG 4.26Å
31	V	96.8	Very high	93.9	Very high	21 Å²	21	102.1 Å²	102.1	13%	0.127	57%	0.566	C	S	.	*	H	α-helix	trans	-55.8	-44.9	179.7	173.2	0	0	0	0	111	P27 A28 G35 G36 K38 V39	P27-V31 WeakPolarHBondContact O-CG2 3.3Å; P27-V31 PolarHBondContact O-N 3.36Å; A28-V31 PolarHBondContact O-N 3.13Å; V31-G35 PolarHBondContact O-N 3.06Å; V31-G35 VanDerWaalsContact O-N 3.08Å; V31-G36 VanDerWaalsContact CG1-O 3.26Å; V31-G36 WeakPolarHBondContact CG1-O 3.36Å; V31-G36 PolarHBondContact O-N 3.28Å; V31-K38 VanDerWaalsContact CG2-O 3.3Å; V31-K38 WeakPolarHBondContact CG2-O 3.26Å; V31-V39 HydrophobicContact CB-CG2 4.37Å; V31-V39 HydrophobicContact CG2-CG2 3.87Å
32	T	96.1	Very high	93.6	Very high	116 Å²	116	109.2 Å²	109.2	71%	0.712	59%	0.591	S	S	*	*	H	α-helix	trans	-64.3	-42.7	179.4	-54.4	0	0	0	0	112.5	A28 E29 F30	A28-T32 PolarHBondContact O-N 2.88Å; A28-T32 PolarHBondContact O-OG1 3.41Å; E29-T32 PolarHBondContact O-N 3.23Å; F30-T32 VanDerWaalsContact C-N 3.27Å; F30-T32 PolarHBondContact O-N 3.08Å
33	R	94.8	Very high	94.1	Very high	188 Å²	188	108.6 Å²	108.6	71%	0.709	59%	0.594	S	S	*	*	H	α-helix	trans	-71.7	-33.9	-178.5	-74.4	-70.7	-169.7	121	3.8	113.2	E29 F30	E29-R33 WeakPolarHBondContact O-CB 3.36Å; E29-R33 WeakPolarHBondContact O-CG 3.3Å; E29-R33 PolarHBondContact O-N 3.07Å; F30-R33 PolarHBondContact O-N 3.33Å
34	F	95.3	Very high	94.3	Very high	119 Å²	119	107.9 Å²	107.9	52%	0.522	59%	0.586	S	S	.	*	H	α-helix	trans	-99.1	6.9	-177.1	-70.3	-89.8	0	0	0	113.6	F22 F30 G36	F22-F34 HydrophobicContact CD1-CE2 4.25Å; F22-F34 HydrophobicContact CZ-CZ 3.81Å; F22-F34 AromaticContact CZ-CZ 3.81Å; F22-F34 HydrophobicContact CZ-CE2 3.62Å; F22-F34 AromaticContact CZ-CE2 3.62Å; F22-F34 AromaticContact CE1-CZ 3.52Å; F22-F34 HydrophobicContact CE1-CE2 3.34Å; F22-F34 AromaticContact CE1-CE2 3.34Å; F22-F34 HydrophobicContact CD1-CZ 4.04Å; F22-F34 HydrophobicContact CE1-CZ 3.52Å; F30-F34 PolarHBondContact O-N 3.48Å; F30-F34 WeakPolarHBondContact O-CD2 3.42Å; F30-F34 VanDerWaalsContact O-CD2 3.3Å; F30-F34 HydrophobicContact CZ-CG 4.14Å; F30-F34 HydrophobicContact CZ-CE2 4.08Å; F30-F34 HydrophobicContact CZ-CD2 3.81Å; F30-F34 AromaticContact CZ-CD2 3.81Å; F30-F34 HydrophobicContact CG-CE2 4.39Å; F30-F34 HydrophobicContact CE2-CD2 3.51Å; F30-F34 HydrophobicContact CG-CD2 4.03Å; F30-F34 HydrophobicContact CE2-CZ 4.03Å; F30-F34 HydrophobicContact CE2-CE2 3.38Å; F30-F34 AromaticContact CE2-CE2 3.38Å; F30-F34 AromaticContact CE2-CD2 3.51Å; F30-F34 HydrophobicContact CE1-CG 4.46Å; F30-F34 HydrophobicContact CE1-CD2 4.2Å; F30-F34 HydrophobicContact CD2-CE2 3.57Å; F30-F34 AromaticContact CD2-CE2 3.57Å; F30-F34 HydrophobicContact CD2-CD2 3.63Å; F30-F34 AromaticContact CD2-CD2 3.63Å; F30-F34 HydrophobicContact CD1-CD2 4.3Å; F30-F34 HydrophobicContact CE2-CG 4.26Å; F34-G36 VanDerWaalsContact C-N 3.32Å; F34-G36 PolarHBondContact O-N 2.99Å
35	G	94.8	Very high	94.2	Very high	70 Å²	70	110.9 Å²	110.9	72%	0.722	60%	0.601	S	S	*	*	T	Hydrogen-bonded Turn	trans	70.9	25.2	175.7	0	0	0	0	0	114.2	V31	V31-G35 PolarHBondContact O-N 3.06Å; V31-G35 VanDerWaalsContact O-N 3.08Å
36	G	96	Very high	94.3	Very high	43 Å²	43	112.2 Å²	112.2	44%	0.443	59%	0.592	S	S	.	*			trans	-77.3	172.3	171.2	0	0	0	0	0	111.9	V31 F34	V31-G36 VanDerWaalsContact CG1-O 3.26Å; V31-G36 WeakPolarHBondContact CG1-O 3.36Å; V31-G36 PolarHBondContact O-N 3.28Å; F34-G36 VanDerWaalsContact C-N 3.32Å; F34-G36 PolarHBondContact O-N 2.99Å
37	N	96.4	Very high	94.2	Very high	164 Å²	164	116.4 Å²	116.4	88%	0.877	61%	0.609	S	S	*	*	S	Bend	trans	-123.9	-4.9	-179.6	64.7	-17.2	0	0	0	114.1
38	K	96.4	Very high	94.1	Very high	157 Å²	157	118.6 Å²	118.6	68%	0.683	61%	0.614	S	S	*	*			trans	-143	129.5	-174.9	-173.7	174.6	-178.8	-178	0	111.5	V31	V31-K38 VanDerWaalsContact CG2-O 3.3Å; V31-K38 WeakPolarHBondContact CG2-O 3.26Å
39	V	95.4	Very high	93.9	Very high	57 Å²	57	123.5 Å²	123.5	35%	0.345	63%	0.629	S	S	.	*			trans	-82.6	134.2	167.1	178.2	0	0	0	0	108.7	P27 A28 V31	P27-V39 HydrophobicContact CB-CG1 3.69Å; A28-V39 HydrophobicContact CB-CG2 4.06Å; V31-V39 HydrophobicContact CB-CG2 4.37Å; V31-V39 HydrophobicContact CG2-CG2 3.87Å
40	I	93.9	Very high	93.8	Very high	149 Å²	149	125.8 Å²	125.8	76%	0.764	64%	0.643	S	S	*	*			trans	-104.3	117.3	175.4	-58.5	174.9	0	0	0	107.7
41	E	88.9	Confident	93.6	Very high	173 Å²	173	127.8 Å²	127.8	81%	0.808	66%	0.66	S	S	*	*			trans	-91.3	148.3	169.4	-63.4	-178.4	175.6	0	0	108.9
42	K	78.3	Confident	93.3	Very high	277 Å²	277	137.5 Å²	137.5	100%	1.204	71%	0.708	S	S	*	*			trans	-74.9	0	-178.5	-176	-173.4	173.8	-171.5	0	111.3

Retrieved 42 of 42 residues in 65.9 ms (Link to these results)

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