A0A087WVX8_HUMAN Loading...

PPFIA binding protein 1

AlphaFold DB , UniProt , Accession A0A087WVX8, Species HUMAN (Homo sapiens, Human), Gene PPFIBP1, Length 86 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1D39.1Very low52.2Low209 Ų209151.7 Ų151.7100%1.11883%0.827SS**  01350-170.113000108.4
2R44Very low52.7Low236 Ų236150.3 Ų150.389%0.89183%0.827SS**  trans33.7119.6-179.2-90.8176.1169.4159.9-2.8122.7
3A48.6Very low53.6Low89 Ų89150.8 Ų150.874%0.73683%0.826SS**  trans-75.2-160.116900000112.8
4P53.9Low54.5Low125 Ų125148.1 Ų148.181%0.81282%0.819SS**  -128.9-178.8-58.629.3-9.8000112
5A61.7Low55.4Low95 Ų95146.5 Ų146.579%0.78582%0.819SS**  trans-45.5146.9177.300000117.9
6E46.9Very low55.7Low196 Ų196149.9 Ų149.992%0.91682%0.815SS**  trans177.1141.3146-102.9172.7-152.900106.5
7S46.4Very low56Low95 Ų95146.2 Ų146.266%0.66480%0.8SS**  cis-162.7131.84.761.40000107.6
8R60.8Low56.2Low235 Ų235145.8 Ų145.889%0.88781%0.806SS**  trans51.5157.3130.5-77.5-174.9176.2-177.2-0122
9P58.6Low56.3Low115 Ų115142.1 Ų142.175%0.74780%0.804SS**  trans-90.4130.6-146.534.6-30.8000111.9G11P9-G11 PolarHBondContact O-N 3.44Å
10F53.2Low56.3Low217 Ų217140.9 Ų140.995%0.95279%0.791SS**  trans-76.272162.1-72.6-78.3000109.1
11G61.3Low56.4Low57 Ų57142 Ų14259%0.58880%0.796SS**  trans-62.6142.9155.300000109.6P9P9-G11 PolarHBondContact O-N 3.44Å
12T58.5Low57.2Low135 Ų135136.2 Ų136.283%0.82877%0.768SS**  trans95.756.6164.3-40.10000117.1
13L64.2Low57.7Low156 Ų156130 Ų13082%0.81776%0.761SS**  trans-141.4138.2132.2-71.3-178.8000109.3
14P66.2Low58.2Low113 Ų113133 Ų13373%0.73476%0.761SS**PPolyproline II helixtrans-58.8137.1175.825.1-32.4000109.2R16P14-R16 PolarHBondContact O-N 3.31Å
15P67.1Low58.2Low125 Ų125131.1 Ų131.181%0.81274%0.744SS**PPolyproline II helixtrans-58.2127.3176.324.1-31.8000108.6
16R61.2Low58.1Low201 Ų201134.4 Ų134.476%0.75875%0.749SS**PPolyproline II helixtrans-57.7127.8-175-164.5179.1-68.3173.2-1.6108.8P14P14-R16 PolarHBondContact O-N 3.31Å
17P61Low58.9Low86 Ų86128.7 Ų128.756%0.55873%0.725SS**PPolyproline II helixtrans-62.8139-18024.6-32.3000109.9G19P17-G19 VanDerWaalsContact O-N 3.14Å; P17-G19 PolarHBondContact O-N 2.98Å
18P58.8Low59.9Low139 Ų139129.9 Ų129.990%0.90373%0.73SS**THydrogen-bonded Turntrans-68.6113.6177.427.6-30.9000108.5
19G59.1Low59.8Low75 Ų75127.7 Ų127.777%0.77373%0.727SS**THydrogen-bonded Turntrans1310179.700000115.9P17 D21P17-G19 VanDerWaalsContact O-N 3.14Å; P17-G19 PolarHBondContact O-N 2.98Å; G19-D21 PolarHBondContact O-N 2.91Å
20Q54.8Low60.1Low118 Ų118124.4 Ų124.455%0.55172%0.715SS**  trans-85.684.3173.2-170.2117.5-39.500111.1T22Q20-T22 HydrophobicContact CG-CG2 3.63Å; Q20-T22 PolarHBondContact O-N 3.49Å
21D58.2Low60.7Low166 Ų166118.1 Ų118.189%0.88869%0.694SS**  trans-72.763.3164.1-73.4-37.8000110.4G19 S23G19-D21 PolarHBondContact O-N 2.91Å; D21-S23 VanDerWaalsContact C-N 3.29Å; D21-S23 PolarHBondContact O-N 3.03Å
22T56.6Low60.9Low86 Ų86125.5 Ų125.553%0.52870%0.704SS.*  trans-89.176.6161.251.40000108Q20 M24Q20-T22 HydrophobicContact CG-CG2 3.63Å; Q20-T22 PolarHBondContact O-N 3.49Å; T22-M24 VanDerWaalsContact C-N 3.26Å
23S55.4Low61.2Low106 Ų106128.1 Ų128.174%0.74170%0.704SS**  trans-101.247.3152.2-174.70000109D21 D25D21-S23 VanDerWaalsContact C-N 3.29Å; D21-S23 PolarHBondContact O-N 3.03Å; S23-D25 PolarHBondContact O-N 3.44Å
24M58.5Low61.3Low152 Ų152126.3 Ų126.375%0.74970%0.699SS**  trans-72.387146.5-70.9-66.5169.800104.1T22 D26T22-M24 VanDerWaalsContact C-N 3.26Å; M24-D26 VanDerWaalsContact C-N 3.31Å; M24-D26 PolarHBondContact O-N 3.31Å
25D54.5Low61.4Low85 Ų85131.6 Ų131.646%0.45571%0.705SS.*  trans-54.4103.1169.9155.480.2000106.2S23 N27 T31S23-D25 PolarHBondContact O-N 3.44Å; D25-N27 PolarHBondContact O-N 3.13Å; D25-N27 WeakPolarHBondContact OD2-CB 3.43Å; D25-T31 HydrophobicContact CB-CG2 3.29Å; D25-T31 VanDerWaalsContact O-CG2 3.26Å; D25-T31 WeakPolarHBondContact O-CG2 3.46Å; D25-T31 WeakPolarHBondContact OD2-CG2 3.43Å
26D59.8Low61.3Low165 Ų165129 Ų12988%0.88269%0.689SS**  trans-66.250.4170-92.3-53.9000109.1M24 P28M24-D26 VanDerWaalsContact C-N 3.31Å; M24-D26 PolarHBondContact O-N 3.31Å; D26-P28 WeakPolarHBondContact O-CD 3.42Å
27N63.7Low61.3Low76 Ų76124.1 Ų124.141%0.40669%0.686SS.*  trans-89.9116.5170.1-169.79.5000107.3D25 F29 G30D25-N27 PolarHBondContact O-N 3.13Å; D25-N27 WeakPolarHBondContact OD2-CB 3.43Å; N27-F29 PolarHBondContact OD1-N 3.06Å; N27-F29 PolarHBondContact O-N 2.98Å; N27-G30 PolarHBondContact O-N 3.21Å
28P66.8Low61.4Low120 Ų120129.1 Ų129.178%0.77970%0.699SS**THydrogen-bonded Turntrans-62.4-7.4175.625.6-33.9000113D26D26-P28 WeakPolarHBondContact O-CD 3.42Å
29F59Low61.8Low188 Ų188124.6 Ų124.683%0.82568%0.678SS**THydrogen-bonded Turntrans-109.526.5171.3-74.5-86.7000114.3N27N27-F29 PolarHBondContact OD1-N 3.06Å; N27-F29 PolarHBondContact O-N 2.98Å
30G65.1Low62.4Low47 Ų47133 Ų13349%0.48569%0.687SS.*  trans86.3111146.500000117.9N27 R32N27-G30 PolarHBondContact O-N 3.21Å; G30-R32 PolarHBondContact O-N 2.93Å
31T65.6Low63.1Low85 Ų85130 Ų13052%0.52169%0.687SS.*SBendtrans-7124.2159.444.10000114.8D25D25-T31 HydrophobicContact CB-CG2 3.29Å; D25-T31 VanDerWaalsContact O-CG2 3.26Å; D25-T31 WeakPolarHBondContact O-CG2 3.46Å; D25-T31 WeakPolarHBondContact OD2-CG2 3.43Å
32R65.5Low63.7Low212 Ų212130 Ų13080%0.868%0.679SS**  trans-107.2115.5-177.3-156.6166.8-63.2-175.93.6108.3G30 V34G30-R32 PolarHBondContact O-N 2.93Å; R32-V34 PolarHBondContact O-N 2.81Å
33K64.7Low64.3Low189 Ų189132.6 Ų132.682%0.82268%0.683SS**  trans-52.994161.8-105.4179.7178.1176.70107.5R35K33-R35 HydrophobicContact CB-CG 4.37Å; K33-R35 PolarHBondContact O-N 3.09Å
34V65.6Low65.1Low118 Ų118136.6 Ų136.672%0.71569%0.688SS**  trans-79.278.1166.8-176.50000105.1R32 S36R32-V34 PolarHBondContact O-N 2.81Å; V34-S36 PolarHBondContact O-N 2.96Å
35R69.4Low65.7Low225 Ų225133.8 Ų133.885%0.84968%0.675SS**  trans-75.575.9160.5-62.2-176.580.7-141.46106.3K33K33-R35 HydrophobicContact CB-CG 4.37Å; K33-R35 PolarHBondContact O-N 3.09Å
36S63.8Low66.5Low70 Ų70139.9 Ų139.949%0.4970%0.697SS.*  trans-112.680.2171.9-156.70000108.4V34 F38 G39V34-S36 PolarHBondContact O-N 2.96Å; S36-F38 VanDerWaalsContact C-N 3.28Å; S36-G39 WeakPolarHBondContact OG-CA 3.49Å; S36-G39 PolarHBondContact OG-N 3.38Å
37S62.2Low66.5Low99 Ų99135.5 Ų135.569%0.69268%0.679SS**THydrogen-bonded Turntrans-76.1-21.1171.757.30000112.1
38F63.1Low66.6Low190 Ų190140.4 Ų140.483%0.83371%0.706SS**THydrogen-bonded Turntrans-132.765.1174.4-49.9-74.1000108.5S36 R40S36-F38 VanDerWaalsContact C-N 3.28Å; F38-R40 PolarHBondContact O-N 3.18Å
39G66.5Low66.7Low45 Ų45143 Ų14346%0.46470%0.704SS.*  trans-55.8131.7172.100000109.7S36 G41S36-G39 WeakPolarHBondContact OG-CA 3.49Å; S36-G39 PolarHBondContact OG-N 3.38Å; G39-G41 WeakPolarHBondContact O-CA 3.13Å; G39-G41 PolarHBondContact O-N 2.8Å
40R71.9Confident67.2Low252 Ų252145.9 Ų145.995%0.95171%0.71SS**SBendtrans-3095.6-173.7-79.2168.4176.9162.7-2.3112.3F38F38-R40 PolarHBondContact O-N 3.18Å
41G69.1Low67.1Low53 Ų53146.8 Ų146.855%0.54671%0.706SS.*  trans-156.640.3-172.300000110.9G39 F43G39-G41 WeakPolarHBondContact O-CA 3.13Å; G39-G41 PolarHBondContact O-N 2.8Å; G41-F43 VanDerWaalsContact C-N 3.32Å; G41-F43 PolarHBondContact O-N 3.16Å
42F70.6Confident67Low167 Ų167148 Ų14873%0.73273%0.725SS**  trans-81.891.416164.2-87.9000106.3K44F42-K44 HydrophobicContact CD2-CG 4.26Å; F42-K44 HydrophobicContact CE2-CG 4.13Å; F42-K44 PolarHBondContact O-N 3.22Å
43F69.2Low67.1Low140 Ų140141.6 Ų141.661%0.61471%0.712SS**  trans-55.7117.4170.339.6-89.1000107.4G41 I45G41-F43 VanDerWaalsContact C-N 3.32Å; G41-F43 PolarHBondContact O-N 3.16Å; F43-I45 HydrophobicContact CD2-CD1 3.87Å; F43-I45 PolarHBondContact O-N 3.04Å; F43-I45 HydrophobicContact CE2-CG1 3.86Å; F43-I45 HydrophobicContact CD2-CG1 3.53Å; F43-I45 HydrophobicContact CE2-CD1 3.62Å
44K71.6Confident66.9Low191 Ų191136.3 Ų136.383%0.8370%0.704SS**  trans-68.8102.1174.3-71.9-176.967.8172.40107.5F42 K46F42-K44 HydrophobicContact CD2-CG 4.26Å; F42-K44 HydrophobicContact CE2-CG 4.13Å; F42-K44 PolarHBondContact O-N 3.22Å; K44-K46 PolarHBondContact O-N 2.88Å
45I71.8Confident66.8Low93 Ų93136 Ų13648%0.47771%0.705SS.*  trans-76.5114.8176.3-55.6167.3000108F43 T51F43-I45 HydrophobicContact CD2-CD1 3.87Å; F43-I45 PolarHBondContact O-N 3.04Å; F43-I45 HydrophobicContact CE2-CG1 3.86Å; F43-I45 HydrophobicContact CD2-CG1 3.53Å; F43-I45 HydrophobicContact CE2-CD1 3.62Å; I45-T51 WeakPolarHBondContact CD1-OG1 3.08Å
46K71.6Confident66.3Low213 Ų213132.1 Ų132.193%0.92670%0.701SS**  trans-107.288159-173.9-171.7167.6-171.10107.6K44K44-K46 PolarHBondContact O-N 2.88Å
47S60.8Low66.3Low72 Ų72136.9 Ų136.950%0.50372%0.72SS.*  trans-148138.9177.5179.20000109.4K49S47-K49 PolarHBondContact O-N 3.09Å; S47-K49 PolarHBondContact OG-N 3.19Å; S47-K49 PolarHBondContact OG-O 3.42Å; S47-K49 VanDerWaalsContact OG-O 3.13Å
48N65.4Low66.3Low180 Ų180133.9 Ų133.996%0.96371%0.705SS**SBendtrans-812.9167-173.743.1000112
49K68.9Low65.9Low173 Ų173131.6 Ų131.675%0.75271%0.707SS**SBendtrans-115.5133.3-177.7-133.1-171.7-73-142.70111S47 T51S47-K49 PolarHBondContact O-N 3.09Å; S47-K49 PolarHBondContact OG-N 3.19Å; S47-K49 PolarHBondContact OG-O 3.42Å; S47-K49 VanDerWaalsContact OG-O 3.13Å; K49-T51 PolarHBondContact O-N 3.07Å
50R68.6Low65.3Low249 Ų249137.9 Ų137.994%0.9472%0.718SS**  trans-55.8120.6-178.4-165.4173.7-175.9173.30.5110.2A52R50-A52 PolarHBondContact O-N 2.7Å
51T64.1Low64.5Low67 Ų67132.9 Ų132.941%0.41171%0.71SS.*  trans-74.1124.1176.9-56.50000108.6I45 K49 S53I45-T51 WeakPolarHBondContact CD1-OG1 3.08Å; K49-T51 PolarHBondContact O-N 3.07Å; T51-S53 PolarHBondContact O-N 2.94Å
52A62.9Low63.9Low110 Ų110139.6 Ų139.691%0.90973%0.727SS**SBendtrans-73.514-173.300000114.7R50R50-A52 PolarHBondContact O-N 2.7Å
53S66.4Low63.1Low77 Ų77138.6 Ų138.654%0.53873%0.729SS.*  trans-10275.1170.865.50000109.6T51T51-S53 PolarHBondContact O-N 2.94Å
54A62Low62.4Low79 Ų79135.7 Ų135.765%0.65373%0.731SS**PPolyproline II helixtrans-101119.3147.800000104.9N56A54-N56 PolarHBondContact O-N 2.87Å
55P63.1Low61.7Low111 Ų111136 Ų13672%0.72173%0.732SS**PPolyproline II helixtrans-56.1128.6-179.923.5-31.9000108.7L57P55-L57 PolarHBondContact O-N 2.91Å; P55-L57 VanDerWaalsContact O-N 3.09Å
56N59.2Low60.8Low144 Ų144135.7 Ų135.777%0.7774%0.744SS**PPolyproline II helixtrans-57.8118173.7-84.5-67.5000107.6A54 G58 Y60A54-N56 PolarHBondContact O-N 2.87Å; N56-G58 PolarHBondContact O-N 2.8Å; N56-Y60 PolarHBondContact O-OH 3.23Å
57L63.7Low60Low169 Ų169133.1 Ų133.189%0.88574%0.74SS**  trans-76.170.8172-65.3173.8000108P55P55-L57 PolarHBondContact O-N 2.91Å; P55-L57 VanDerWaalsContact O-N 3.09Å
58G61.7Low59.8Low37 Ų37137.2 Ų137.238%0.38175%0.754SS.*  trans-77.8131.2161.500000108N56 Y60N56-G58 PolarHBondContact O-N 2.8Å; G58-Y60 PolarHBondContact O-N 3.28Å; G58-Y60 WeakPolarHBondContact O-CD2 3.02Å; G58-Y60 WeakPolarHBondContact O-CE2 3.26Å
59T54.3Low59Low142 Ų142135.4 Ų135.487%0.87174%0.744SS**  trans-61.1105.9174.947.40000109.2
60Y53.9Low57.9Low177 Ų177133.4 Ų133.469%0.69475%0.749SS**  trans-88.7121.7171.2-44.1-77.9000107.9N56 G58N56-Y60 PolarHBondContact O-OH 3.23Å; G58-Y60 PolarHBondContact O-N 3.28Å; G58-Y60 WeakPolarHBondContact O-CD2 3.02Å; G58-Y60 WeakPolarHBondContact O-CE2 3.26Å
61D56.3Low56.6Low147 Ų147129.5 Ų129.579%0.78674%0.741SS**  trans-55.1150173.6-72-45.5000111.2N63D61-N63 PolarHBondContact O-N 2.77Å
62Q56.1Low56Low194 Ų194129.8 Ų129.891%0.90776%0.757SS**SBendtrans-63.89.2-162.3-63.4177.4-700116.6
63N53.5Low55.5Low145 Ų145128.1 Ų128.178%0.77575%0.75SS**  trans-113.336.5178-70.6-8.1000112.8D61 F65D61-N63 PolarHBondContact O-N 2.77Å; N63-F65 PolarHBondContact O-N 2.8Å
64A55Low54.6Low79 Ų79131.6 Ų131.665%0.65376%0.756SS**  trans-70.172.8177.200000112.6
65F55.6Low54.3Low197 Ų197136.9 Ų136.986%0.86477%0.767SS**  trans-107.29160.3-67.2-74.7000112.4N63 L67N63-F65 PolarHBondContact O-N 2.8Å; F65-L67 PolarHBondContact O-N 3.03Å; F65-L67 VanDerWaalsContact O-N 3.16Å
66A54Low53.4Low87 Ų87137.9 Ų137.972%0.71976%0.762SS**  trans-72.9107.5175.400000110.4I68A66-I68 PolarHBondContact O-N 2.85Å
67L54.6Low53.1Low160 Ų160136.9 Ų136.984%0.83877%0.765SS**  trans-69.8106.3164-65.3174.4000108F65 L69F65-L67 PolarHBondContact O-N 3.03Å; F65-L67 VanDerWaalsContact O-N 3.16Å; L67-L69 PolarHBondContact O-N 2.91Å; L67-L69 VanDerWaalsContact O-N 3.09Å
68I56.9Low53Low158 Ų158135.2 Ų135.281%0.8176%0.756SS**  trans-73.1101.5168.4-59.4-170.6000107.3A66 P70A66-I68 PolarHBondContact O-N 2.85Å; I68-P70 WeakPolarHBondContact O-CD 3Å
69L47.3Very low52.9Low142 Ų142138.9 Ų138.974%0.74377%0.773SS**  trans-75.2122.3167.8-66.2174.1000108.4L67 Q71L67-L69 PolarHBondContact O-N 2.91Å; L67-L69 VanDerWaalsContact O-N 3.09Å; L69-Q71 PolarHBondContact O-N 3.05Å
70P46.6Very low52.8Low131 Ų131141.4 Ų141.485%0.85177%0.773SS**  trans-78.177.2169.332.5-31.5000108I68I68-P70 WeakPolarHBondContact O-CD 3Å
71Q41.1Very low53.2Low167 Ų167138.1 Ų138.178%0.7877%0.773SS**  trans-102.7105.9161.7-152.9165.564.100107.1L69 G73L69-Q71 PolarHBondContact O-N 3.05Å; Q71-G73 PolarHBondContact O-N 2.76Å
72G51Low53.4Low73 Ų73142.3 Ų142.375%0.75378%0.779SS**  trans-51.3137.5176.300000111.2
73G52.8Low53.7Low74 Ų74137.1 Ų137.176%0.76376%0.764SS**SBendtrans66.961.8151.900000115.6Q71Q71-G73 PolarHBondContact O-N 2.76Å
74K48.5Very low53.8Low151 Ų151139.7 Ų139.766%0.65777%0.769SS**  trans-178.7105.3132.746.3-158.6167.566.80108.5Q76K74-Q76 VanDerWaalsContact C-N 3.27Å; K74-Q76 PolarHBondContact O-N 3.2Å
75E54.4Low53.8Low190 Ų190144.1 Ų144.189%0.88878%0.78SS**  trans-50.891.1165.1-53.1-68.3130.500108.5
76Q45.3Very low53.6Low131 Ų131146.4 Ų146.461%0.61279%0.793SS**  trans-123.181.2166.4-70.6-165.450.900106.8K74 L78K74-Q76 VanDerWaalsContact C-N 3.27Å; K74-Q76 PolarHBondContact O-N 3.2Å; Q76-L78 PolarHBondContact O-N 2.89Å
77C52.2Low53.6Low123 Ų123149.4 Ų149.483%0.83180%0.796SS**  trans-61.789.7158.8-86.50000107.7P79C77-P79 WeakPolarHBondContact O-CD 3.11Å
78L61.9Low53.5Low134 Ų134148.8 Ų148.870%0.70279%0.794SS**PPolyproline II helixtrans-82.5116.6162.5-62.1-176.1000106.7Q76 F80Q76-L78 PolarHBondContact O-N 2.89Å; L78-F80 PolarHBondContact O-N 3.3Å
79P60Low53.3Low114 Ų114148.3 Ų148.374%0.7479%0.793SS**PPolyproline II helixtrans-61.9123.8173.226.6-31.6000107.3C77C77-P79 WeakPolarHBondContact O-CD 3.11Å
80F51.3Low53.7Low196 Ų196148.6 Ų148.686%0.8680%0.796SS**PPolyproline II helixtrans-54.6128.1165.8-77.9-80.8000107.4L78 Y82L78-F80 PolarHBondContact O-N 3.3Å; F80-Y82 PolarHBondContact O-N 3.2Å
81P62.9Low54.1Low107 Ų107149.8 Ų149.870%0.69579%0.793SS**PPolyproline II helixtrans-60.2129.7176.524-31.5000108.6S83P81-S83 PolarHBondContact O-N 3.14Å
82Y60Low55Low236 Ų236148.6 Ų148.693%0.92579%0.794SS**SBendtrans-68.169.1177.4-134.4-89.4000109.3F80F80-Y82 PolarHBondContact O-N 3.2Å
83S61.8Low55.2Low85 Ų85154 Ų15459%0.59480%0.796SS**  trans-163.984.5-176.7-550000105.5P81P81-S83 PolarHBondContact O-N 3.14Å
84F56.8Low55.4Low199 Ų199160.2 Ų160.287%0.87380%0.799SS**  -171.388.695.8-108.5-104.5000106.4
85I55Low56Low171 Ų171160.9 Ų160.988%0.87781%0.811SS**  trans-89.7117.7157-61.7-68.3000105.5
86H50.7Low56.2Low245 Ų245158.3 Ų158.3100%1.13480%0.804SS**  trans-150.90153.9-164.6-61.5000109.4

Retrieved 86 of 86 residues in 42 ms (Link to these results)