A0A087WW05_HUMAN Loading...

Aspartate beta-hydroxylase

AlphaFold DB , UniProt , Accession A0A087WW05, Species HUMAN (Homo sapiens, Human), Gene ASPH, Length 44 aa.

						>A0A087WW05_HUMAN|A0A087WW05|ASPH
EDNPVEDSQVIVEEVSIFPVEEQQEVPPGYLMENMESELPWDES
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	E	56.6	Low	71.5	Confident	244 Å²	244	148.6 Å²	148.6	100%	1.14	80%	0.799	S	S	*	*				0	91.7	0	-159.8	170.7	104.7	105.3	N3	E1-N3 PolarHBondContact O-N 3.36Å
2	D	66.7	Low	72.2	Confident	165 Å²	165	146.8 Å²	146.8	88%	0.882	80%	0.796	S	S	*	*			trans	-79.8	104.3	174.8	-101.8	-91.3	0	106	P4	D2-P4 VanDerWaalsContact O-CD 3.28Å; D2-P4 WeakPolarHBondContact O-CD 3.28Å
3	N	68.1	Low	72.8	Confident	130 Å²	130	149.4 Å²	149.4	70%	0.695	80%	0.8	S	S	*	*			trans	-85	108.8	172.4	-171.8	2.5	0	106.9	E1 V5	E1-N3 PolarHBondContact O-N 3.36Å; N3-V5 PolarHBondContact O-N 2.83Å
4	P	70.2	Confident	73.2	Confident	100 Å²	100	150.9 Å²	150.9	65%	0.649	80%	0.799	S	S	*	*			trans	-67.4	104.6	172.4	28.9	-30.7	0	106.4	D2 E6	D2-P4 VanDerWaalsContact O-CD 3.28Å; D2-P4 WeakPolarHBondContact O-CD 3.28Å; P4-E6 PolarHBondContact O-N 2.96Å
5	V	72.6	Confident	73.7	Confident	116 Å²	116	148.8 Å²	148.8	70%	0.703	79%	0.794	S	S	*	*			trans	-60.3	100.2	164.5	169.6	0	0	105	N3 D7	N3-V5 PolarHBondContact O-N 2.83Å; V5-D7 VanDerWaalsContact C-N 3.34Å; V5-D7 PolarHBondContact O-N 2.93Å
6	E	69.6	Low	74.2	Confident	179 Å²	179	143.9 Å²	143.9	84%	0.836	78%	0.776	S	S	*	*			trans	-65	102.3	171.9	-70.4	-162.4	95.2	106.5	P4 S8	P4-E6 PolarHBondContact O-N 2.96Å; E6-S8 PolarHBondContact O-N 3.26Å
7	D	73.4	Confident	74.7	Confident	138 Å²	138	144.3 Å²	144.3	74%	0.738	78%	0.775	S	S	*	*			trans	-57.6	93.6	168.5	-80.9	-67.8	0	107.5	V5 Q9	V5-D7 VanDerWaalsContact C-N 3.34Å; V5-D7 PolarHBondContact O-N 2.93Å; D7-Q9 VanDerWaalsContact C-N 3.34Å; D7-Q9 PolarHBondContact O-N 2.87Å
8	S	77.1	Confident	75.1	Confident	113 Å²	113	145.6 Å²	145.6	79%	0.79	77%	0.773	S	S	*	*			trans	-66.9	96.8	178.6	-160.6	0	0	107.7	E6 V10	E6-S8 PolarHBondContact O-N 3.26Å; S8-V10 PolarHBondContact O-N 2.79Å
9	Q	74.6	Confident	75.4	Confident	169 Å²	169	144.1 Å²	144.1	79%	0.79	77%	0.773	S	S	*	*			trans	-71.1	115.6	180	-65.8	-173.1	-1.8	109.1	D7 I11	D7-Q9 VanDerWaalsContact C-N 3.34Å; D7-Q9 PolarHBondContact O-N 2.87Å; Q9-I11 PolarHBondContact O-N 3.32Å
10	V	78.6	Confident	75.7	Confident	128 Å²	128	143.6 Å²	143.6	78%	0.776	78%	0.775	S	S	*	*			trans	-78.1	109.1	173.1	178.5	0	0	108.1	S8 V12	S8-V10 PolarHBondContact O-N 2.79Å; V10-V12 HydrophobicContact CG1-CG1 4.42Å
11	I	78.6	Confident	75.9	Confident	153 Å²	153	145.3 Å²	145.3	79%	0.785	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-83.6	116.7	173.9	-60.5	161.7	0	107.3	Q9	Q9-I11 PolarHBondContact O-N 3.32Å
12	V	80.4	Confident	77	Confident	126 Å²	126	143 Å²	143	76%	0.764	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-90.3	122.7	173.8	-64.5	0	0	109.1	V10	V10-V12 HydrophobicContact CG1-CG1 4.42Å
13	E	80.3	Confident	77.6	Confident	181 Å²	181	144.4 Å²	144.4	85%	0.846	77%	0.768	S	S	*	*	P	Polyproline II helix	trans	-79.3	125.1	172.5	-68.4	-175.3	102.2	109.2	V15	E13-V15 PolarHBondContact O-N 3.48Å
14	E	78.5	Confident	78.1	Confident	170 Å²	170	146.6 Å²	146.6	79%	0.794	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-74.8	122.8	173.7	-171.9	-143.3	112.8	109.2
15	V	80.7	Confident	78.6	Confident	120 Å²	120	150.1 Å²	150.1	73%	0.727	78%	0.782	S	S	*	*			trans	-101.5	108.1	172.3	-173.4	0	0	108.4	E13	E13-V15 PolarHBondContact O-N 3.48Å
16	S	81.9	Confident	79	Confident	71 Å²	71	148.6 Å²	148.6	50%	0.497	77%	0.773	S	S	.	*			trans	-76.2	122.9	172.8	-179.7	0	0	110.2
17	I	81.3	Confident	79.7	Confident	150 Å²	150	142.9 Å²	142.9	77%	0.769	75%	0.751	S	S	*	*			trans	-103	111.3	176.4	-51.6	171.2	0	107
18	F	83.3	Confident	79.6	Confident	167 Å²	167	141.2 Å²	141.2	73%	0.732	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-71.9	134.4	173.5	-67	-83.7	0	109.6	V20	F18-V20 PolarHBondContact O-N 3.4Å
19	P	80.5	Confident	79.5	Confident	118 Å²	118	137.8 Å²	137.8	77%	0.766	73%	0.73	S	S	*	*	P	Polyproline II helix	trans	-62.1	130	171.7	26.4	-31.8	0	108.6	E21	P19-E21 PolarHBondContact O-N 3.32Å
20	V	81.8	Confident	79	Confident	134 Å²	134	136.4 Å²	136.4	81%	0.812	72%	0.719	S	S	*	*	P	Polyproline II helix	trans	-66.7	127.7	169.9	169.7	0	0	107.3	F18 E22	F18-V20 PolarHBondContact O-N 3.4Å; V20-E22 PolarHBondContact O-N 3.29Å
21	E	79.5	Confident	78.4	Confident	179 Å²	179	134.9 Å²	134.9	84%	0.836	71%	0.706	S	S	*	*	P	Polyproline II helix	trans	-61.3	123.8	171.8	-66.5	-177.5	104.5	109	P19 Q23	P19-E21 PolarHBondContact O-N 3.32Å; E21-Q23 PolarHBondContact O-N 3.16Å
22	E	79.8	Confident	77.7	Confident	195 Å²	195	133.9 Å²	133.9	91%	0.911	70%	0.699	S	S	*	*	P	Polyproline II helix	trans	-66.1	119.1	176	-66.3	-170.8	103.5	108.8	V20 Q24	V20-E22 PolarHBondContact O-N 3.29Å; E22-Q24 PolarHBondContact O-N 3.22Å; E22-Q24 VanDerWaalsContact O-N 3.16Å
23	Q	77.9	Confident	76.7	Confident	195 Å²	195	133.8 Å²	133.8	91%	0.911	69%	0.69	S	S	*	*	P	Polyproline II helix	trans	-66.5	116.8	172.9	-64.9	-174	-54.1	108.2	E21 E25	E21-Q23 PolarHBondContact O-N 3.16Å; Q23-E25 PolarHBondContact O-N 3.18Å
24	Q	79.4	Confident	75.8	Confident	176 Å²	176	129.6 Å²	129.6	82%	0.822	67%	0.674	S	S	*	*	P	Polyproline II helix	trans	-62.6	123.4	176	-174.5	176.1	-7.4	109.3	E22 V26	E22-Q24 PolarHBondContact O-N 3.22Å; E22-Q24 VanDerWaalsContact O-N 3.16Å; Q24-V26 PolarHBondContact O-N 3.27Å
25	E	81.8	Confident	74.9	Confident	174 Å²	174	127.5 Å²	127.5	81%	0.813	67%	0.666	S	S	*	*	P	Polyproline II helix	trans	-61.5	119.2	170.2	-175.6	176.1	91.7	108.5	Q23 P27	Q23-E25 PolarHBondContact O-N 3.18Å; E25-P27 WeakPolarHBondContact O-CD 3.38Å
26	V	80.9	Confident	74	Confident	84 Å²	84	128.5 Å²	128.5	51%	0.509	66%	0.663	S	S	.	*	P	Polyproline II helix	trans	-79.3	119.5	174.3	-179.2	0	0	107.3	Q24 Y30 L31	Q24-V26 PolarHBondContact O-N 3.27Å; V26-Y30 HydrophobicContact CG1-CG 4.42Å; V26-L31 HydrophobicContact CG1-CD2 4.4Å; V26-L31 HydrophobicContact CG1-CG 4.5Å
27	P	82.9	Confident	72.9	Confident	60 Å²	60	129.1 Å²	129.1	39%	0.39	67%	0.667	S	S	.	*	P	Polyproline II helix	trans	-60.4	143.6	178.4	-18.4	28.8	0	110.4	E25 G29 Y30	E25-P27 WeakPolarHBondContact O-CD 3.38Å; P27-G29 PolarHBondContact O-N 2.95Å; P27-Y30 PolarHBondContact O-N 2.95Å; P27-Y30 HydrophobicContact CB-CE2 4.31Å; P27-Y30 HydrophobicContact CG-CE2 3.81Å; P27-Y30 HydrophobicContact CB-CD2 3.86Å; P27-Y30 HydrophobicContact CG-CD2 3.68Å
28	P	72.3	Confident	72	Confident	103 Å²	103	129.4 Å²	129.4	67%	0.669	67%	0.665	S	S	*	*	T	Hydrogen-bonded Turn	trans	-60.4	-18.9	-172.5	22.1	-33.4	0	114.3
29	G	73.6	Confident	70.9	Confident	40 Å²	40	127 Å²	127	41%	0.412	66%	0.659	S	S	.	*	T	Hydrogen-bonded Turn	trans	-74.1	-26.2	174.7	0	0	0	114.8	P27 L31 M32	P27-G29 PolarHBondContact O-N 2.95Å; G29-L31 VanDerWaalsContact C-N 3.3Å; G29-L31 PolarHBondContact O-N 3.33Å; G29-M32 PolarHBondContact O-N 3.41Å
30	Y	65.3	Low	70.2	Confident	141 Å²	141	126.7 Å²	126.7	55%	0.553	66%	0.657	S	S	*	*	H	α-helix	trans	-71.7	-24.9	-179.1	-84.4	-93.5	0	113	V26 P27 M32 N34	V26-Y30 HydrophobicContact CG1-CG 4.42Å; P27-Y30 PolarHBondContact O-N 2.95Å; P27-Y30 HydrophobicContact CB-CE2 4.31Å; P27-Y30 HydrophobicContact CG-CE2 3.81Å; P27-Y30 HydrophobicContact CB-CD2 3.86Å; P27-Y30 HydrophobicContact CG-CD2 3.68Å; Y30-M32 VanDerWaalsContact C-N 3.34Å; Y30-N34 PolarHBondContact O-OD1 3.3Å
31	L	64.8	Low	69.6	Low	96 Å²	96	131 Å²	131	50%	0.503	66%	0.659	S	S	.	*	H	α-helix	trans	-74.8	-27.4	177.4	-62.8	177.1	0	111.9	V26 G29 M35	V26-L31 HydrophobicContact CG1-CD2 4.4Å; V26-L31 HydrophobicContact CG1-CG 4.5Å; G29-L31 VanDerWaalsContact C-N 3.3Å; G29-L31 PolarHBondContact O-N 3.33Å; L31-M35 VanDerWaalsContact O-CG 3.29Å; L31-M35 WeakPolarHBondContact O-CG 3.29Å; L31-M35 PolarHBondContact O-N 3.22Å
32	M	63.9	Low	68.8	Low	131 Å²	131	129.5 Å²	129.5	65%	0.645	66%	0.656	S	S	*	*	H	α-helix	trans	-72.8	-44.8	-179.6	-66.7	-179	179.1	111.5	G29 Y30 N34 M35 E36	G29-M32 PolarHBondContact O-N 3.41Å; Y30-M32 VanDerWaalsContact C-N 3.34Å; M32-N34 PolarHBondContact O-N 3.35Å; M32-M35 PolarHBondContact O-N 3.24Å; M32-E36 PolarHBondContact O-N 3.23Å; M32-E36 VanDerWaalsContact O-N 3.14Å; M32-E36 WeakPolarHBondContact O-CG 3.48Å
33	E	60.2	Low	67.9	Low	124 Å²	124	129.7 Å²	129.7	58%	0.579	66%	0.657	S	S	*	*	H	α-helix	trans	-62.7	-31.6	177.8	-69.5	-176.5	92.2	112.5	S37	E33-S37 PolarHBondContact O-N 2.93Å; E33-S37 PolarHBondContact O-OG 3.2Å
34	N	60.9	Low	67.1	Low	94 Å²	94	129 Å²	129	50%	0.503	67%	0.673	S	S	.	*	H	α-helix	trans	-75.9	-35.9	178.6	-69.8	21.1	0	112.3	Y30 M32 E36 S37 E38	Y30-N34 PolarHBondContact O-OD1 3.3Å; M32-N34 PolarHBondContact O-N 3.35Å; N34-E36 VanDerWaalsContact C-N 3.34Å; N34-S37 PolarHBondContact O-N 3.14Å; N34-E38 PolarHBondContact O-N 3.23Å
35	M	61.2	Low	66.5	Low	126 Å²	126	126.6 Å²	126.6	62%	0.621	67%	0.666	S	S	*	*	H	α-helix	trans	-69.9	-31.6	175.7	-72.7	171.5	179.3	112.3	L31 M32 S37	L31-M35 VanDerWaalsContact O-CG 3.29Å; L31-M35 WeakPolarHBondContact O-CG 3.29Å; L31-M35 PolarHBondContact O-N 3.22Å; M32-M35 PolarHBondContact O-N 3.24Å; M35-S37 VanDerWaalsContact C-N 3.27Å
36	E	60	Low	65.7	Low	141 Å²	141	124.1 Å²	124.1	66%	0.659	66%	0.658	S	S	*	*	H	α-helix	trans	-69	-27.6	172.7	-68.2	-176	109.3	112.2	M32 N34	M32-E36 PolarHBondContact O-N 3.23Å; M32-E36 VanDerWaalsContact O-N 3.14Å; M32-E36 WeakPolarHBondContact O-CG 3.48Å; N34-E36 VanDerWaalsContact C-N 3.34Å
37	S	60.1	Low	64.8	Low	83 Å²	83	126.3 Å²	126.3	58%	0.58	67%	0.667	S	S	*	*	H	α-helix	trans	-83.9	-18.7	178.8	-57	0	0	114	E33 N34 M35	E33-S37 PolarHBondContact O-N 2.93Å; E33-S37 PolarHBondContact O-OG 3.2Å; N34-S37 PolarHBondContact O-N 3.14Å; M35-S37 VanDerWaalsContact C-N 3.27Å
38	E	62.2	Low	63.7	Low	156 Å²	156	130.2 Å²	130.2	73%	0.729	68%	0.683	S	S	*	*	S	Bend	trans	-92.6	-0	176.3	-71.7	-177.7	102.9	113.4	N34 P40	N34-E38 PolarHBondContact O-N 3.23Å; E38-P40 WeakPolarHBondContact O-CD 3.38Å
39	L	60.2	Low	63.2	Low	118 Å²	118	131.9 Å²	131.9	62%	0.618	68%	0.684	S	S	*	*	S	Bend	trans	-62.4	119.4	167.7	-66.3	177.6	0	107.5	W41	L39-W41 PolarHBondContact O-N 2.89Å
40	P	66.5	Low	62.5	Low	110 Å²	110	138.1 Å²	138.1	71%	0.714	70%	0.702	S	S	*	*			trans	-56.8	119.9	173.6	24.6	-31.2	0	105.9	E38 D42	E38-P40 WeakPolarHBondContact O-CD 3.38Å; P40-D42 PolarHBondContact O-N 2.94Å
41	W	67.6	Low	62.3	Low	226 Å²	226	137.9 Å²	137.9	86%	0.856	71%	0.712	S	S	*	*			trans	-43.6	113.2	170.5	-24.3	83	0	105.9	L39 E43	L39-W41 PolarHBondContact O-N 2.89Å; W41-E43 PolarHBondContact O-N 2.98Å
42	D	64.4	Low	62.1	Low	146 Å²	146	141.1 Å²	141.1	78%	0.781	73%	0.729	S	S	*	*			trans	-48.5	114.4	-178	-155.6	-103.4	0	106.8	P40 S44	P40-D42 PolarHBondContact O-N 2.94Å; D42-S44 VanDerWaalsContact C-N 3.35Å; D42-S44 PolarHBondContact O-N 2.86Å
43	E	60.5	Low	62	Low	200 Å²	200	141.9 Å²	141.9	94%	0.935	74%	0.736	S	S	*	*			trans	-60.2	98.4	178.8	-77.9	-175.8	93.7	107.7	W41	W41-E43 PolarHBondContact O-N 2.98Å
44	S	59.9	Low	62.1	Low	179 Å²	179	143.5 Å²	143.5	100%	1.252	75%	0.75	S	S	*	*			trans	-108.2	0	167	-73.3	0	0	110.7	D42	D42-S44 VanDerWaalsContact C-N 3.35Å; D42-S44 PolarHBondContact O-N 2.86Å

Retrieved 44 of 44 residues in 28.3 ms (Link to these results)

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