A0A087WWI2_HUMAN Loading...

Phosphodiesterase 4D interacting protein

AlphaFold DB , UniProt , Accession A0A087WWI2, Species HUMAN (Homo sapiens, Human), Gene PDE4DIP, Length 143 aa.

						>A0A087WWI2_HUMAN|A0A087WWI2|PDE4DIP
MKPHSRKGDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADV
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	42.4	Very low	43.5	Very low	249 Å²	249	166.5 Å²	166.5	100%	1.227	82%	0.818	S	S	*	*				0	114	0	-73.6	155.4	78.4	0	0	109.1
2	K	45.9	Very low	43.8	Very low	204 Å²	204	161 Å²	161	89%	0.887	82%	0.82	S	S	*	*			trans	-117.7	169.5	150	-94.2	-168.7	-179.4	-178	0	105.4
3	P	61.6	Low	43.8	Very low	100 Å²	100	158.5 Å²	158.5	65%	0.649	80%	0.802	S	S	*	*			cis	-128.8	-174.2	-10.9	26.8	-4.3	0	0	0	110.5
4	H	39	Very low	44.1	Very low	185 Å²	185	158.5 Å²	158.5	86%	0.856	81%	0.806	S	S	*	*			trans	-152.1	112.5	140.1	-102.6	70.9	0	0	0	109.2
5	S	45.2	Very low	44.7	Very low	102 Å²	102	157.9 Å²	157.9	71%	0.713	81%	0.806	S	S	*	*			trans	-72.2	152.7	167.9	-55.3	0	0	0	0	111.4
6	R	41.2	Very low	44.6	Very low	219 Å²	219	151.5 Å²	151.5	83%	0.826	79%	0.791	S	S	*	*			trans	-168.2	112.1	136.5	-102.8	178.5	-106.1	-166.6	-1.9	106.2
7	K	38.8	Very low	44.6	Very low	190 Å²	190	153.2 Å²	153.2	83%	0.826	79%	0.794	S	S	*	*				46.7	104.4	96.3	-71.2	-176.1	177.1	-177.5	0	108.8
8	G	49.8	Very low	44.9	Very low	74 Å²	74	155.2 Å²	155.2	76%	0.763	80%	0.802	S	S	*	*				84.7	80.1	50.7	0	0	0	0	0	106.1
9	D	37.6	Very low	45.1	Very low	122 Å²	122	152.9 Å²	152.9	65%	0.652	80%	0.795	S	S	*	*			trans	-142.4	104.2	-174.6	-84.2	-11.8	0	0	0	109.1
10	Y	37.1	Very low	45.1	Very low	202 Å²	202	150.2 Å²	150.2	79%	0.792	79%	0.787	S	S	*	*			trans	68.6	103.7	141.7	-51.6	-70.3	0	0	0	120	A12	Y10-A12 PolarHBondContact O-N 3.26Å
11	F	40	Very low	45.3	Very low	184 Å²	184	154.9 Å²	154.9	81%	0.807	79%	0.794	S	S	*	*			trans	-18.2	122.5	133.8	-90.5	-106.7	0	0	0	113	E13	F11-E13 HydrophobicContact CD1-CG 4.14Å; F11-E13 WeakPolarHBondContact CD1-OE1 3.43Å; F11-E13 VanDerWaalsContact CE1-OE1 3.26Å; F11-E13 WeakPolarHBondContact CE1-OE1 3.42Å
12	A	46.6	Very low	45.6	Very low	101 Å²	101	148.3 Å²	148.3	84%	0.835	77%	0.768	S	S	*	*			trans	-106.4	96.2	152.1	0	0	0	0	0	106.1	Y10 D14	Y10-A12 PolarHBondContact O-N 3.26Å; A12-D14 PolarHBondContact O-N 3.02Å
13	E	43.9	Very low	45.3	Very low	128 Å²	128	144 Å²	144	60%	0.598	76%	0.764	S	S	*	*			trans	-67.4	120.3	158.4	-66.1	-73	149.8	0	0	105.8	F11 D15	F11-E13 HydrophobicContact CD1-CG 4.14Å; F11-E13 WeakPolarHBondContact CD1-OE1 3.43Å; F11-E13 VanDerWaalsContact CE1-OE1 3.26Å; F11-E13 WeakPolarHBondContact CE1-OE1 3.42Å; E13-D15 VanDerWaalsContact C-N 3.31Å; E13-D15 PolarHBondContact O-N 3.3Å; E13-D15 VanDerWaalsContact O-N 3.13Å
14	D	47.6	Very low	44.6	Very low	159 Å²	159	148.3 Å²	148.3	85%	0.85	78%	0.775	S	S	*	*			trans	-79.1	88.7	170.7	-175.1	36.2	0	0	0	106.9	A12 G16	A12-D14 PolarHBondContact O-N 3.02Å; D14-G16 PolarHBondContact O-N 2.87Å
15	D	53	Low	45	Very low	150 Å²	150	146.2 Å²	146.2	80%	0.802	78%	0.775	S	S	*	*			trans	-70.8	74.3	175.1	-59.2	-30	0	0	0	109.8	E13	E13-D15 VanDerWaalsContact C-N 3.31Å; E13-D15 PolarHBondContact O-N 3.3Å; E13-D15 VanDerWaalsContact O-N 3.13Å
16	G	44.3	Very low	45.2	Very low	55 Å²	55	146.3 Å²	146.3	57%	0.567	78%	0.783	S	S	*	*			trans	-104.2	93.4	171.5	0	0	0	0	0	110.8	D14 M18	D14-G16 PolarHBondContact O-N 2.87Å; G16-M18 PolarHBondContact O-N 3.15Å; G16-M18 VanDerWaalsContact O-N 3.14Å
17	E	43.8	Very low	45.5	Very low	180 Å²	180	139.4 Å²	139.4	84%	0.841	77%	0.772	S	S	*	*			trans	-44.7	118.9	170.7	-78.1	-174.5	142.6	0	0	111.7	V19	E17-V19 HydrophobicContact CB-CG2 4.5Å; E17-V19 PolarHBondContact O-N 3.01Å
18	M	49.5	Very low	45.6	Very low	190 Å²	190	139.4 Å²	139.4	94%	0.936	77%	0.773	S	S	*	*			trans	-74.4	88.6	168.2	-80.7	-88.1	-171	0	0	109.2	G16 P20	G16-M18 PolarHBondContact O-N 3.15Å; G16-M18 VanDerWaalsContact O-N 3.14Å; M18-P20 WeakPolarHBondContact O-CD 3.4Å
19	V	48.9	Very low	45.7	Very low	111 Å²	111	144.4 Å²	144.4	67%	0.673	78%	0.781	S	S	*	*			trans	-74.3	122.5	169.7	-175.1	0	0	0	0	108.8	E17 R21	E17-V19 HydrophobicContact CB-CG2 4.5Å; E17-V19 PolarHBondContact O-N 3.01Å; V19-R21 PolarHBondContact O-N 3.49Å
20	P	44.7	Very low	46	Very low	99 Å²	99	143.7 Å²	143.7	64%	0.643	79%	0.785	S	S	*	*			trans	-64.2	124.9	171.3	25.8	-31.5	0	0	0	108.8	M18 T22	M18-P20 WeakPolarHBondContact O-CD 3.4Å; P20-T22 PolarHBondContact O-N 3.08Å
21	R	49.3	Very low	46.6	Very low	249 Å²	249	140.9 Å²	140.9	94%	0.94	78%	0.784	S	S	*	*			trans	-64.5	87.8	168.3	-78.3	-179.2	83.4	125.3	-1.3	108.4	V19 S23	V19-R21 PolarHBondContact O-N 3.49Å; R21-S23 PolarHBondContact O-N 2.92Å
22	T	49.8	Very low	46.9	Very low	110 Å²	110	138.5 Å²	138.5	68%	0.675	79%	0.785	S	S	*	*			trans	-72.3	114.7	165.5	57.3	0	0	0	0	107.1	P20 H24	P20-T22 PolarHBondContact O-N 3.08Å; T22-H24 PolarHBondContact O-N 3.09Å
23	S	40.2	Very low	47	Very low	115 Å²	115	142.6 Å²	142.6	80%	0.804	78%	0.784	S	S	*	*			trans	-59.7	120.6	173.9	-68.2	0	0	0	0	109.2	R21 T25	R21-S23 PolarHBondContact O-N 2.92Å; S23-T25 PolarHBondContact O-N 3.3Å
24	H	46.9	Very low	46.9	Very low	189 Å²	189	142.9 Å²	142.9	88%	0.875	79%	0.79	S	S	*	*			trans	-51.6	117.3	179.9	-58.9	-87.8	0	0	0	111.9	T22	T22-H24 PolarHBondContact O-N 3.09Å
25	T	47.2	Very low	47	Very low	141 Å²	141	146.4 Å²	146.4	87%	0.865	79%	0.791	S	S	*	*			trans	-148	80.4	158.2	-51.7	0	0	0	0	108.5	S23	S23-T25 PolarHBondContact O-N 3.3Å
26	A	48.9	Very low	46.4	Very low	105 Å²	105	142.5 Å²	142.5	87%	0.868	79%	0.786	S	S	*	*			trans	-155	84.3	169.5	0	0	0	0	0	110.6
27	A	48.5	Very low	46.6	Very low	73 Å²	73	146 Å²	146	60%	0.603	80%	0.798	S	S	*	*			trans	-173.2	120.5	154.3	0	0	0	0	0	104.3
28	F	40.8	Very low	46.8	Very low	190 Å²	190	143 Å²	143	83%	0.833	80%	0.795	S	S	*	*			cis	-156.3	130.1	39.7	-68.1	-95	0	0	0	109.1
29	L	50.5	Low	46.7	Very low	179 Å²	179	139.9 Å²	139.9	94%	0.937	79%	0.786	S	S	*	*			trans	-112.7	114.9	151	-77	172.7	0	0	0	106.2
30	S	43.9	Very low	46.2	Very low	107 Å²	107	142.5 Å²	142.5	75%	0.748	79%	0.791	S	S	*	*			trans	-145	98.5	164.8	-59.4	0	0	0	0	108.6
31	D	49.5	Very low	46.4	Very low	143 Å²	143	142.3 Å²	142.3	77%	0.765	79%	0.792	S	S	*	*			trans	-56.4	126.6	163.5	178.9	22.6	0	0	0	110.3	K33	D31-K33 PolarHBondContact OD1-N 3.35Å
32	T	46.2	Very low	46	Very low	134 Å²	134	138 Å²	138	82%	0.822	78%	0.783	S	S	*	*			trans	-137.7	82	158.2	49.1	0	0	0	0	109.1	D34	T32-D34 PolarHBondContact O-N 3.02Å
33	K	50.5	Low	45.6	Very low	188 Å²	188	139.6 Å²	139.6	82%	0.817	79%	0.785	S	S	*	*			trans	-62.1	99.5	153	-176.2	175.7	-177.7	177.4	0	109.7	D31	D31-K33 PolarHBondContact OD1-N 3.35Å
34	D	42	Very low	45.2	Very low	134 Å²	134	145 Å²	145	72%	0.717	79%	0.788	S	S	*	*			trans	-167.2	117.4	138.8	-137.7	18.3	0	0	0	114.7	T32	T32-D34 PolarHBondContact O-N 3.02Å
35	R	47.7	Very low	44.9	Very low	233 Å²	233	147.1 Å²	147.1	88%	0.879	79%	0.789	S	S	*	*			trans	66.4	109.6	131.7	-144.4	155.8	-158.5	144.5	2.1	123.1
36	G	41.9	Very low	44.4	Very low	68 Å²	68	145.8 Å²	145.8	70%	0.701	79%	0.785	S	S	*	*			trans	-150.4	148.5	147.2	0	0	0	0	0	110.4
37	P	47.8	Very low	44.5	Very low	127 Å²	127	144.2 Å²	144.2	83%	0.825	78%	0.779	S	S	*	*			trans	-87.6	167	-140	18.9	-7.6	0	0	0	117.1
38	P	48.2	Very low	43.9	Very low	119 Å²	119	149.7 Å²	149.7	77%	0.773	79%	0.792	S	S	*	*			trans	-82.8	153.6	-169.2	34.8	-34.3	0	0	0	113.6
39	V	46.8	Very low	44.4	Very low	123 Å²	123	150.7 Å²	150.7	75%	0.745	80%	0.796	S	S	*	*			trans	15.8	109.6	148.4	165.3	0	0	0	0	115.8	S41	V39-S41 WeakPolarHBondContact CG1-OG 3.43Å
40	Q	40	Very low	43.9	Very low	167 Å²	167	148.7 Å²	148.7	78%	0.78	79%	0.791	S	S	*	*			trans	-96.6	91.9	153.9	-168.5	173.5	3	0	0	108.6	Q42	Q40-Q42 HydrophobicContact CG-CG 4.11Å; Q40-Q42 PolarHBondContact O-N 2.97Å
41	S	48.9	Very low	44	Very low	95 Å²	95	149.1 Å²	149.1	66%	0.664	79%	0.791	S	S	*	*			trans	-60	118.5	158.8	-67	0	0	0	0	108.7	V39	V39-S41 WeakPolarHBondContact CG1-OG 3.43Å
42	Q	39.7	Very low	44	Very low	159 Å²	159	150.5 Å²	150.5	74%	0.743	79%	0.79	S	S	*	*			trans	-125	102.9	160.5	-78.3	-101.1	-40.5	0	0	107.2	Q40	Q40-Q42 HydrophobicContact CG-CG 4.11Å; Q40-Q42 PolarHBondContact O-N 2.97Å
43	I	41.8	Very low	43.9	Very low	142 Å²	142	148.9 Å²	148.9	73%	0.728	78%	0.78	S	S	*	*			trans	-101	129.3	174.2	-121.6	157.1	0	0	0	106.2
44	W	32.1	Very low	43.8	Very low	229 Å²	229	148 Å²	148	87%	0.867	78%	0.779	S	S	*	*			trans	61	103	164.5	-49.8	106.2	0	0	0	119.7
45	R	40.3	Very low	44.1	Very low	234 Å²	234	146.8 Å²	146.8	88%	0.883	78%	0.777	S	S	*	*			trans	-113.8	111.4	143.8	-81.9	-77.3	-152.4	-104.1	-0.5	108.4
46	S	35.8	Very low	44.3	Very low	113 Å²	113	144.5 Å²	144.5	79%	0.79	77%	0.769	S	S	*	*			trans	40.6	123.1	148	-146.8	0	0	0	0	119.6
47	G	51	Low	45	Very low	71 Å²	71	145.2 Å²	145.2	73%	0.732	76%	0.763	S	S	*	*			trans	-61.7	141.7	168.5	0	0	0	0	0	113.3
48	E	35.9	Very low	45	Very low	189 Å²	189	146.3 Å²	146.3	88%	0.883	76%	0.762	S	S	*	*			trans	-143.6	123.5	147	-112.4	173.1	159.4	0	0	107.3
49	K	51.3	Low	45.1	Very low	211 Å²	211	150.5 Å²	150.5	92%	0.917	76%	0.762	S	S	*	*			trans	-88	112.6	-179.6	-52.8	-176.2	-176.2	-174.6	0	106.8
50	V	40.9	Very low	45.3	Very low	136 Å²	136	148.5 Å²	148.5	82%	0.824	76%	0.758	S	S	*	*			trans	-98.9	123.2	165.7	-162.2	0	0	0	0	107.7	F52	V50-F52 PolarHBondContact O-N 2.99Å
51	P	46.2	Very low	45.7	Very low	116 Å²	116	148.7 Å²	148.7	75%	0.753	76%	0.757	S	S	*	*			trans	-78.7	121.3	-173.2	30.2	-31.2	0	0	0	111.4	V53	P51-V53 PolarHBondContact O-N 3.39Å
52	F	48.8	Very low	46	Very low	172 Å²	172	151.3 Å²	151.3	75%	0.754	76%	0.758	S	S	*	*	S	Bend	trans	30.6	88.5	132	-166.6	-94.2	0	0	0	116.7	V50	V50-F52 PolarHBondContact O-N 2.99Å
53	V	45.3	Very low	47	Very low	100 Å²	100	151.1 Å²	151.1	61%	0.606	76%	0.755	S	S	*	*				-165.6	68.6	127.8	-167.2	0	0	0	0	108.6	P51 Y56	P51-V53 PolarHBondContact O-N 3.39Å; V53-Y56 HydrophobicContact CG1-CE1 3.85Å
54	Q	46.6	Very low	47.8	Very low	170 Å²	170	148.2 Å²	148.2	79%	0.794	75%	0.745	S	S	*	*			trans	-144.5	50.5	167.2	-122.1	167.9	36.3	0	0	110.1
55	T	49.7	Very low	49.2	Very low	108 Å²	108	140.7 Å²	140.7	66%	0.663	73%	0.726	S	S	*	*			trans	-109.4	15.2	-179.7	42.4	0	0	0	0	113.3
56	Y	52.1	Low	50.3	Low	186 Å²	186	136 Å²	136	73%	0.729	71%	0.714	S	S	*	*	S	Bend	trans	-99.5	10.4	176.8	43.6	-106.7	0	0	0	115.5	V53	V53-Y56 HydrophobicContact CG1-CE1 3.85Å
57	S	55.1	Low	51.6	Low	82 Å²	82	136.2 Å²	136.2	57%	0.573	71%	0.71	S	S	*	*	S	Bend	trans	-131	12.5	179.3	-164.3	0	0	0	0	116.8
58	L	49.2	Very low	52.4	Low	151 Å²	151	138.7 Å²	138.7	79%	0.791	70%	0.703	S	S	*	*	S	Bend	trans	-103.5	-1.7	177	-74.4	-173.5	0	0	0	115.5
59	R	50.1	Low	54.5	Low	207 Å²	207	131.9 Å²	131.9	78%	0.781	67%	0.674	S	S	*	*	S	Bend	trans	-95.1	-7.9	176.8	-140.5	-173.3	-68.4	179.1	-2.7	114.2	F61 E62	R59-F61 PolarHBondContact O-N 3.38Å; R59-E62 VanDerWaalsContact CG-OE2 3.28Å; R59-E62 WeakPolarHBondContact CG-OE2 3.28Å
60	A	49.8	Very low	56.2	Low	80 Å²	80	125.8 Å²	125.8	66%	0.661	65%	0.649	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.8	-7.9	-177.7	0	0	0	0	0	114
61	F	50	Low	58.5	Low	172 Å²	172	121 Å²	121	75%	0.754	62%	0.624	S	S	*	*	T	Hydrogen-bonded Turn	trans	-122.4	10.5	-177.3	-63.8	-74.8	0	0	0	114.4	R59 K63	R59-F61 PolarHBondContact O-N 3.38Å; F61-K63 PolarHBondContact O-N 2.91Å
62	E	53.5	Low	60.8	Low	149 Å²	149	121.1 Å²	121.1	70%	0.696	62%	0.618	S	S	*	*	S	Bend	trans	-70.1	-12.8	176.2	-76.1	-175.7	155.7	0	0	113.4	R59	R59-E62 VanDerWaalsContact CG-OE2 3.28Å; R59-E62 WeakPolarHBondContact CG-OE2 3.28Å
63	K	60.5	Low	63	Low	156 Å²	156	119.8 Å²	119.8	68%	0.678	61%	0.608	S	S	*	*	S	Bend	trans	-106.7	113.7	168.1	-75.4	174.1	-180	174.2	0	108	F61	F61-K63 PolarHBondContact O-N 2.91Å
64	P	58.9	Low	65.3	Low	80 Å²	80	118.3 Å²	118.3	52%	0.519	60%	0.596	S	S	.	*			trans	-51.7	144.4	163.9	-10.4	19	0	0	0	107.9	Q66 T69	P64-Q66 PolarHBondContact O-N 2.92Å; P64-T69 HydrophobicContact CB-CG2 3.96Å; P64-T69 HydrophobicContact CG-CG2 4.32Å
65	P	62.8	Low	67.7	Low	71 Å²	71	117 Å²	117	46%	0.461	59%	0.588	S	S	.	*			trans	-50.2	116.6	-178.9	-25	34.2	0	0	0	108.5	V67 Q68 T69	P65-V67 PolarHBondContact O-N 3.05Å; P65-Q68 HydrophobicContact CB-CB 4.39Å; P65-Q68 HydrophobicContact CB-CG 4.06Å; P65-Q68 HydrophobicContact CG-CG 4.36Å; P65-Q68 WeakPolarHBondContact O-CA 3.42Å; P65-Q68 WeakPolarHBondContact O-CB 3.46Å; P65-Q68 PolarHBondContact O-N 3.41Å; P65-T69 PolarHBondContact O-N 2.97Å
66	Q	62.4	Low	69.9	Low	135 Å²	135	117.6 Å²	117.6	63%	0.631	58%	0.583	S	S	*	*	H	α-helix	trans	-57.2	-25	-172.7	-71.7	164.2	-25	0	0	111.8	P64 T69 Q70	P64-Q66 PolarHBondContact O-N 2.92Å; Q66-T69 PolarHBondContact O-N 3.34Å; Q66-T69 PolarHBondContact O-OG1 3.25Å; Q66-Q70 WeakPolarHBondContact O-CB 3.29Å; Q66-Q70 PolarHBondContact O-N 3.45Å
67	V	62.6	Low	72.1	Confident	118 Å²	118	114.2 Å²	114.2	72%	0.715	57%	0.573	S	S	*	*	H	α-helix	trans	-64.7	-41	171.9	-177	0	0	0	0	112.1	P65 Q70 A71	P65-V67 PolarHBondContact O-N 3.05Å; V67-Q70 PolarHBondContact O-N 3.46Å; V67-A71 WeakPolarHBondContact O-CB 3.38Å; V67-A71 PolarHBondContact O-N 3.18Å
68	Q	68.9	Low	74.1	Confident	123 Å²	123	115.4 Å²	115.4	58%	0.575	57%	0.569	S	S	*	*	H	α-helix	trans	-68.2	-39	176.3	-69.9	179.6	21.5	0	0	111.4	P65 A71 L72	P65-Q68 HydrophobicContact CB-CB 4.39Å; P65-Q68 HydrophobicContact CB-CG 4.06Å; P65-Q68 HydrophobicContact CG-CG 4.36Å; P65-Q68 WeakPolarHBondContact O-CA 3.42Å; P65-Q68 WeakPolarHBondContact O-CB 3.46Å; P65-Q68 PolarHBondContact O-N 3.41Å; Q68-A71 PolarHBondContact O-N 3.46Å; Q68-L72 VanDerWaalsContact O-CG 3.28Å; Q68-L72 WeakPolarHBondContact O-CG 3.29Å; Q68-L72 PolarHBondContact O-N 2.99Å; Q68-L72 VanDerWaalsContact O-N 3.08Å
69	T	79	Confident	76.5	Confident	46 Å²	46	112.4 Å²	112.4	28%	0.282	55%	0.553	S	S	.	*	H	α-helix	trans	-70.9	-32.7	177.4	60.9	0	0	0	0	112.3	P64 P65 Q66 R73	P64-T69 HydrophobicContact CB-CG2 3.96Å; P64-T69 HydrophobicContact CG-CG2 4.32Å; P65-T69 PolarHBondContact O-N 2.97Å; Q66-T69 PolarHBondContact O-N 3.34Å; Q66-T69 PolarHBondContact O-OG1 3.25Å; T69-R73 WeakPolarHBondContact O-CG 3.38Å; T69-R73 PolarHBondContact O-N 3.44Å
70	Q	88.3	Confident	78.8	Confident	84 Å²	84	105.6 Å²	105.6	39%	0.393	53%	0.532	S	S	.	.	H	α-helix	trans	-69.2	-46.1	173	-170.2	55.6	37.4	0	0	112	Q66 V67 L72 R73 D74	Q66-Q70 WeakPolarHBondContact O-CB 3.29Å; Q66-Q70 PolarHBondContact O-N 3.45Å; V67-Q70 PolarHBondContact O-N 3.46Å; Q70-L72 VanDerWaalsContact C-N 3.29Å; Q70-L72 PolarHBondContact O-N 2.94Å; Q70-R73 WeakPolarHBondContact O-CB 3.47Å; Q70-R73 PolarHBondContact O-N 3.44Å; Q70-D74 PolarHBondContact NE2-OD1 2.77Å; Q70-D74 VanDerWaalsContact O-CG 3.3Å; Q70-D74 PolarHBondContact O-N 2.96Å
71	A	89.5	Confident	81.1	Confident	36 Å²	36	104.1 Å²	104.1	30%	0.298	51%	0.513	S	S	.	.	H	α-helix	trans	-57.4	-42.3	177.1	0	0	0	0	0	112	V67 Q68 R73 D74 F75	V67-A71 WeakPolarHBondContact O-CB 3.38Å; V67-A71 PolarHBondContact O-N 3.18Å; Q68-A71 PolarHBondContact O-N 3.46Å; A71-R73 VanDerWaalsContact C-N 3.35Å; A71-R73 PolarHBondContact O-N 3.47Å; A71-D74 PolarHBondContact O-N 3.34Å; A71-F75 HydrophobicContact CB-CE2 4.33Å; A71-F75 WeakPolarHBondContact O-CD2 3.25Å; A71-F75 WeakPolarHBondContact O-CG 3.4Å; A71-F75 PolarHBondContact O-N 3.33Å
72	L	94.2	Very high	83.4	Confident	118 Å²	118	100.6 Å²	100.6	62%	0.618	50%	0.502	S	S	*	.	H	α-helix	trans	-61.2	-41	175.6	-72.5	171	0	0	0	112.6	Q68 Q70 F75 E76	Q68-L72 VanDerWaalsContact O-CG 3.28Å; Q68-L72 WeakPolarHBondContact O-CG 3.29Å; Q68-L72 PolarHBondContact O-N 2.99Å; Q68-L72 VanDerWaalsContact O-N 3.08Å; Q70-L72 VanDerWaalsContact C-N 3.29Å; Q70-L72 PolarHBondContact O-N 2.94Å; L72-F75 PolarHBondContact O-N 3.07Å; L72-E76 PolarHBondContact O-N 3.48Å
73	R	94.4	Very high	85.6	Confident	144 Å²	144	99.7 Å²	99.7	54%	0.543	50%	0.496	S	S	.	.	H	α-helix	trans	-66.1	-38.2	176	-74.2	-168.4	-76.7	-128.9	2.2	112.4	T69 Q70 A71 E76 K77	T69-R73 WeakPolarHBondContact O-CG 3.38Å; T69-R73 PolarHBondContact O-N 3.44Å; Q70-R73 WeakPolarHBondContact O-CB 3.47Å; Q70-R73 PolarHBondContact O-N 3.44Å; A71-R73 VanDerWaalsContact C-N 3.35Å; A71-R73 PolarHBondContact O-N 3.47Å; R73-E76 PolarHBondContact O-N 3.15Å; R73-K77 WeakPolarHBondContact O-CB 3.28Å; R73-K77 PolarHBondContact O-N 2.86Å
74	D	94.7	Very high	87.4	Confident	69 Å²	69	99 Å²	99	37%	0.369	49%	0.492	S	S	.	.	H	α-helix	trans	-67.8	-39.4	177.3	-61.5	-24.6	0	0	0	111.1	Q70 A71 K77 H78	Q70-D74 PolarHBondContact NE2-OD1 2.77Å; Q70-D74 VanDerWaalsContact O-CG 3.3Å; Q70-D74 PolarHBondContact O-N 2.96Å; A71-D74 PolarHBondContact O-N 3.34Å; D74-K77 PolarHBondContact O-N 2.93Å; D74-H78 PolarHBondContact O-N 2.89Å; D74-H78 PolarHBondContact O-ND1 2.89Å
75	F	96.6	Very high	89.3	Confident	141 Å²	141	101 Å²	101	62%	0.618	50%	0.495	S	S	*	.	H	α-helix	trans	-62.7	-44.2	172.5	-73	-55.3	0	0	0	112.5	A71 L72 K77 H78 L79	A71-F75 HydrophobicContact CB-CE2 4.33Å; A71-F75 WeakPolarHBondContact O-CD2 3.25Å; A71-F75 WeakPolarHBondContact O-CG 3.4Å; A71-F75 PolarHBondContact O-N 3.33Å; L72-F75 PolarHBondContact O-N 3.07Å; F75-K77 VanDerWaalsContact C-N 3.31Å; F75-K77 PolarHBondContact O-N 3.47Å; F75-H78 PolarHBondContact O-N 3.3Å; F75-L79 VanDerWaalsContact O-CB 3.28Å; F75-L79 WeakPolarHBondContact O-CB 3.25Å; F75-L79 PolarHBondContact O-N 3.44Å
76	E	96.1	Very high	91	Very high	121 Å²	121	102.2 Å²	102.2	57%	0.565	50%	0.498	S	S	*	.	H	α-helix	trans	-61.5	-41.2	176.6	-176.6	173	-161	0	0	111.5	L72 R73 L79 N80	L72-E76 PolarHBondContact O-N 3.48Å; R73-E76 PolarHBondContact O-N 3.15Å; E76-L79 PolarHBondContact O-N 2.96Å; E76-N80 WeakPolarHBondContact O-CB 3.39Å; E76-N80 PolarHBondContact O-N 3.11Å; E76-N80 PolarHBondContact O-ND2 3.39Å; E76-N80 VanDerWaalsContact O-ND2 3.09Å
77	K	97.5	Very high	92.7	Very high	115 Å²	115	101.9 Å²	101.9	50%	0.5	49%	0.494	S	S	.	.	H	α-helix	trans	-60.3	-52.6	174.2	-177	-174.8	173.1	-64.4	0	111.4	R73 D74 F75 L79 N80 D81	R73-K77 WeakPolarHBondContact O-CB 3.28Å; R73-K77 PolarHBondContact O-N 2.86Å; D74-K77 PolarHBondContact O-N 2.93Å; F75-K77 VanDerWaalsContact C-N 3.31Å; F75-K77 PolarHBondContact O-N 3.47Å; K77-L79 VanDerWaalsContact C-N 3.26Å; K77-L79 PolarHBondContact O-N 3.46Å; K77-N80 PolarHBondContact O-N 2.94Å; K77-N80 VanDerWaalsContact O-N 3.1Å; K77-D81 IonicContact NZ-OD2 3.77Å; K77-D81 PolarHBondContact NZ-OD2 3.48Å; K77-D81 PolarHBondContact O-N 2.87Å
78	H	98.2	Very high	94.4	Very high	107 Å²	107	99.7 Å²	99.7	50%	0.495	48%	0.484	S	S	.	.	H	α-helix	trans	-58.9	-40.2	178.9	-69.7	154.2	0	0	0	111.9	D74 F75 N80 D81 L82	D74-H78 PolarHBondContact O-N 2.89Å; D74-H78 PolarHBondContact O-ND1 2.89Å; F75-H78 PolarHBondContact O-N 3.3Å; H78-N80 VanDerWaalsContact C-N 3.32Å; H78-N80 PolarHBondContact O-N 3.34Å; H78-D81 PolarHBondContact O-N 2.89Å; H78-L82 WeakPolarHBondContact O-CB 3.46Å; H78-L82 WeakPolarHBondContact O-CD1 3.31Å; H78-L82 PolarHBondContact O-N 3.46Å
79	L	98.2	Very high	95.8	Very high	88 Å²	88	98.2 Å²	98.2	46%	0.461	48%	0.48	S	S	.	.	H	α-helix	trans	-63.1	-39.2	176.8	-175.2	143.1	0	0	0	112	F75 E76 K77 K83	F75-L79 VanDerWaalsContact O-CB 3.28Å; F75-L79 WeakPolarHBondContact O-CB 3.25Å; F75-L79 PolarHBondContact O-N 3.44Å; E76-L79 PolarHBondContact O-N 2.96Å; K77-L79 VanDerWaalsContact C-N 3.26Å; K77-L79 PolarHBondContact O-N 3.46Å; L79-K83 HydrophobicContact CD2-CD 3.89Å; L79-K83 VanDerWaalsContact CD2-NZ 3.33Å; L79-K83 WeakPolarHBondContact O-CB 3.43Å; L79-K83 VanDerWaalsContact O-CG 3.31Å; L79-K83 WeakPolarHBondContact O-CG 3.46Å; L79-K83 PolarHBondContact O-N 2.93Å
80	N	98.3	Very high	96.8	Very high	65 Å²	65	103 Å²	103	35%	0.348	50%	0.497	S	S	.	.	H	α-helix	trans	-69.2	-39.9	175.2	-74.6	-37.9	0	0	0	112.5	E76 K77 H78 K83 K84	E76-N80 WeakPolarHBondContact O-CB 3.39Å; E76-N80 PolarHBondContact O-N 3.11Å; E76-N80 PolarHBondContact O-ND2 3.39Å; E76-N80 VanDerWaalsContact O-ND2 3.09Å; K77-N80 PolarHBondContact O-N 2.94Å; K77-N80 VanDerWaalsContact O-N 3.1Å; H78-N80 VanDerWaalsContact C-N 3.32Å; H78-N80 PolarHBondContact O-N 3.34Å; N80-K83 PolarHBondContact O-N 2.93Å; N80-K84 WeakPolarHBondContact O-CG 3.42Å; N80-K84 PolarHBondContact O-N 3.23Å
81	D	98.4	Very high	97.3	Very high	49 Å²	49	102.4 Å²	102.4	26%	0.262	50%	0.496	S	S	.	.	H	α-helix	trans	-63.3	-47.3	175.9	-68	-21.6	0	0	0	110.4	K77 H78 K83 K84 E85	K77-D81 IonicContact NZ-OD2 3.77Å; K77-D81 PolarHBondContact NZ-OD2 3.48Å; K77-D81 PolarHBondContact O-N 2.87Å; H78-D81 PolarHBondContact O-N 2.89Å; D81-K83 VanDerWaalsContact C-N 3.33Å; D81-K83 PolarHBondContact O-N 3.39Å; D81-K84 WeakPolarHBondContact O-CB 3.43Å; D81-K84 PolarHBondContact O-N 2.96Å; D81-K84 VanDerWaalsContact O-N 3.08Å; D81-E85 PolarHBondContact O-N 3.48Å
82	L	98.7	Very high	97.7	Very high	98 Å²	98	109.1 Å²	109.1	51%	0.513	51%	0.514	S	S	.	.	H	α-helix	trans	-58.6	-39.4	173.3	-96.2	136.4	0	0	0	113.2	H78 K84 N86	H78-L82 WeakPolarHBondContact O-CB 3.46Å; H78-L82 WeakPolarHBondContact O-CD1 3.31Å; H78-L82 PolarHBondContact O-N 3.46Å; L82-K84 VanDerWaalsContact C-N 3.35Å; L82-N86 VanDerWaalsContact O-CB 3.29Å; L82-N86 WeakPolarHBondContact O-CB 3.36Å; L82-N86 PolarHBondContact O-N 3.39Å; L82-N86 PolarHBondContact O-ND2 3.02Å; L82-N86 VanDerWaalsContact O-ND2 3.1Å
83	K	98.6	Very high	97.9	Very high	129 Å²	129	107.7 Å²	107.7	56%	0.561	51%	0.506	S	S	*	.	H	α-helix	trans	-63.2	-41	174.7	-80.3	174.6	176.5	173.7	0	111.7	L79 N80 D81 F87	L79-K83 HydrophobicContact CD2-CD 3.89Å; L79-K83 VanDerWaalsContact CD2-NZ 3.33Å; L79-K83 WeakPolarHBondContact O-CB 3.43Å; L79-K83 VanDerWaalsContact O-CG 3.31Å; L79-K83 WeakPolarHBondContact O-CG 3.46Å; L79-K83 PolarHBondContact O-N 2.93Å; N80-K83 PolarHBondContact O-N 2.93Å; D81-K83 VanDerWaalsContact C-N 3.33Å; D81-K83 PolarHBondContact O-N 3.39Å; K83-F87 WeakPolarHBondContact O-CB 3.41Å; K83-F87 PolarHBondContact O-N 3.25Å
84	K	98.6	Very high	98.1	Very high	141 Å²	141	106.9 Å²	106.9	61%	0.613	50%	0.504	S	S	*	.	H	α-helix	trans	-66.8	-44.8	177.3	-70.8	171.2	-175.6	170.5	0	111.5	N80 D81 L82 F87 S88	N80-K84 WeakPolarHBondContact O-CG 3.42Å; N80-K84 PolarHBondContact O-N 3.23Å; D81-K84 WeakPolarHBondContact O-CB 3.43Å; D81-K84 PolarHBondContact O-N 2.96Å; D81-K84 VanDerWaalsContact O-N 3.08Å; L82-K84 VanDerWaalsContact C-N 3.35Å; K84-F87 PolarHBondContact O-N 2.94Å; K84-S88 WeakPolarHBondContact O-CB 3.5Å; K84-S88 PolarHBondContact O-N 3.17Å
85	E	98.6	Very high	98.2	Very high	123 Å²	123	108.8 Å²	108.8	58%	0.575	51%	0.508	S	S	*	.	H	α-helix	trans	-60.5	-47.5	175.3	-72.7	-180	-173.1	0	0	110.9	D81 F87 S88 L89	D81-E85 PolarHBondContact O-N 3.48Å; E85-F87 VanDerWaalsContact C-N 3.3Å; E85-F87 PolarHBondContact O-N 3.49Å; E85-S88 WeakPolarHBondContact O-CB 3.39Å; E85-S88 PolarHBondContact O-N 2.9Å; E85-S88 VanDerWaalsContact O-N 3.17Å; E85-L89 WeakPolarHBondContact O-CB 3.36Å; E85-L89 VanDerWaalsContact O-CG 3.27Å; E85-L89 WeakPolarHBondContact O-CG 3.47Å; E85-L89 PolarHBondContact O-N 3.41Å
86	N	98.5	Very high	98.3	Very high	97 Å²	97	106.4 Å²	106.4	52%	0.519	50%	0.502	S	S	.	.	H	α-helix	trans	-59.7	-38.9	175.8	-84.1	-43.5	0	0	0	112.9	L82 K90	L82-N86 VanDerWaalsContact O-CB 3.29Å; L82-N86 WeakPolarHBondContact O-CB 3.36Å; L82-N86 PolarHBondContact O-N 3.39Å; L82-N86 PolarHBondContact O-ND2 3.02Å; L82-N86 VanDerWaalsContact O-ND2 3.1Å; N86-K90 WeakPolarHBondContact O-CB 3.34Å; N86-K90 PolarHBondContact O-N 2.94Å
87	F	98.8	Very high	98.3	Very high	128 Å²	128	106.3 Å²	106.3	56%	0.561	50%	0.501	S	S	*	.	H	α-helix	trans	-66.3	-45.6	174.8	179.9	-103.5	0	0	0	111.7	K83 K84 E85 L89 K90 L91	K83-F87 WeakPolarHBondContact O-CB 3.41Å; K83-F87 PolarHBondContact O-N 3.25Å; K84-F87 PolarHBondContact O-N 2.94Å; E85-F87 VanDerWaalsContact C-N 3.3Å; E85-F87 PolarHBondContact O-N 3.49Å; F87-L89 VanDerWaalsContact C-N 3.33Å; F87-L89 PolarHBondContact O-N 2.91Å; F87-K90 PolarHBondContact O-N 3.47Å; F87-L91 HydrophobicContact CD1-CD1 4.08Å; F87-L91 HydrophobicContact CE1-CD1 3.46Å; F87-L91 VanDerWaalsContact CE1-CD1 3.46Å; F87-L91 HydrophobicContact CE1-CG 4.14Å; F87-L91 HydrophobicContact CZ-CD1 3.77Å; F87-L91 HydrophobicContact CZ-CD2 4.29Å; F87-L91 HydrophobicContact CZ-CG 4.11Å; F87-L91 PolarHBondContact O-N 3.34Å
88	S	98.7	Very high	98.2	Very high	72 Å²	72	104.7 Å²	104.7	50%	0.503	50%	0.496	S	S	.	.	H	α-helix	trans	-59.1	-44.3	175.9	-176	0	0	0	0	111.8	K84 E85 L91 R92	K84-S88 WeakPolarHBondContact O-CB 3.5Å; K84-S88 PolarHBondContact O-N 3.17Å; E85-S88 WeakPolarHBondContact O-CB 3.39Å; E85-S88 PolarHBondContact O-N 2.9Å; E85-S88 VanDerWaalsContact O-N 3.17Å; S88-L91 PolarHBondContact O-N 3.05Å; S88-R92 WeakPolarHBondContact O-CB 3.47Å; S88-R92 PolarHBondContact O-N 3.12Å
89	L	98.8	Very high	98.1	Very high	92 Å²	92	106.8 Å²	106.8	48%	0.482	50%	0.499	S	S	.	.	H	α-helix	trans	-62.9	-44.7	176.2	-72.1	173.1	0	0	0	111.4	E85 F87 L91 R92 I93	E85-L89 WeakPolarHBondContact O-CB 3.36Å; E85-L89 VanDerWaalsContact O-CG 3.27Å; E85-L89 WeakPolarHBondContact O-CG 3.47Å; E85-L89 PolarHBondContact O-N 3.41Å; F87-L89 VanDerWaalsContact C-N 3.33Å; F87-L89 PolarHBondContact O-N 2.91Å; L89-L91 VanDerWaalsContact C-N 3.32Å; L89-L91 PolarHBondContact O-N 3.26Å; L89-R92 PolarHBondContact O-N 3.17Å; L89-R92 VanDerWaalsContact O-N 3.15Å; L89-I93 WeakPolarHBondContact O-CB 3.43Å; L89-I93 VanDerWaalsContact O-CG1 3.29Å; L89-I93 WeakPolarHBondContact O-CG1 3.16Å; L89-I93 PolarHBondContact O-N 3.01Å
90	K	98.6	Very high	97.9	Very high	147 Å²	147	109.2 Å²	109.2	64%	0.639	51%	0.51	S	S	*	.	H	α-helix	trans	-57.3	-45.5	176.3	-174.7	-179.6	-64.6	-174.8	0	111.8	N86 F87 I93 Y94	N86-K90 WeakPolarHBondContact O-CB 3.34Å; N86-K90 PolarHBondContact O-N 2.94Å; F87-K90 PolarHBondContact O-N 3.47Å; K90-I93 PolarHBondContact O-N 3.46Å; K90-Y94 WeakPolarHBondContact O-CB 3.47Å; K90-Y94 PolarHBondContact O-N 3.46Å
91	L	98.6	Very high	97.7	Very high	71 Å²	71	111.1 Å²	111.1	37%	0.372	52%	0.517	S	S	.	.	H	α-helix	trans	-62.6	-43.5	176.2	-69.6	-179.6	0	0	0	111.8	F87 S88 L89 Y94 F95	F87-L91 HydrophobicContact CD1-CD1 4.08Å; F87-L91 HydrophobicContact CE1-CD1 3.46Å; F87-L91 VanDerWaalsContact CE1-CD1 3.46Å; F87-L91 HydrophobicContact CE1-CG 4.14Å; F87-L91 HydrophobicContact CZ-CD1 3.77Å; F87-L91 HydrophobicContact CZ-CD2 4.29Å; F87-L91 HydrophobicContact CZ-CG 4.11Å; F87-L91 PolarHBondContact O-N 3.34Å; S88-L91 PolarHBondContact O-N 3.05Å; L89-L91 VanDerWaalsContact C-N 3.32Å; L89-L91 PolarHBondContact O-N 3.26Å; L91-Y94 PolarHBondContact O-N 3.21Å; L91-F95 HydrophobicContact CB-CE2 4.35Å; L91-F95 WeakPolarHBondContact O-CD2 3.44Å; L91-F95 PolarHBondContact O-N 3.37Å
92	R	98.4	Very high	97.3	Very high	177 Å²	177	114.3 Å²	114.3	67%	0.668	53%	0.53	S	S	*	.	H	α-helix	trans	-64.1	-42.7	179.2	-173.8	167.6	174.2	164	-3.1	112	S88 L89 L96	S88-R92 WeakPolarHBondContact O-CB 3.47Å; S88-R92 PolarHBondContact O-N 3.12Å; L89-R92 PolarHBondContact O-N 3.17Å; L89-R92 VanDerWaalsContact O-N 3.15Å; R92-L96 HydrophobicContact CG-CD1 4.03Å; R92-L96 WeakPolarHBondContact O-CB 3.39Å; R92-L96 WeakPolarHBondContact O-CD1 3.33Å; R92-L96 WeakPolarHBondContact O-CG 3.26Å; R92-L96 PolarHBondContact O-N 3.16Å; R92-L96 VanDerWaalsContact O-N 3.09Å
93	I	98.4	Very high	96.9	Very high	88 Å²	88	116.6 Å²	116.6	45%	0.451	54%	0.536	S	S	.	.	H	α-helix	trans	-61.5	-51.4	175.3	-69.3	165.5	0	0	0	109.7	L89 K90 F95 L96 E97	L89-I93 WeakPolarHBondContact O-CB 3.43Å; L89-I93 VanDerWaalsContact O-CG1 3.29Å; L89-I93 WeakPolarHBondContact O-CG1 3.16Å; L89-I93 PolarHBondContact O-N 3.01Å; K90-I93 PolarHBondContact O-N 3.46Å; I93-F95 PolarHBondContact O-N 3.34Å; I93-L96 WeakPolarHBondContact O-CB 3.44Å; I93-L96 PolarHBondContact O-N 3.13Å; I93-L96 VanDerWaalsContact O-N 3.07Å; I93-E97 VanDerWaalsContact CG2-CD 3.48Å; I93-E97 HydrophobicContact CG2-CG 4.1Å; I93-E97 VanDerWaalsContact CG2-OE1 3.3Å; I93-E97 WeakPolarHBondContact CG2-OE1 3.26Å; I93-E97 WeakPolarHBondContact O-CB 3.34Å; I93-E97 WeakPolarHBondContact O-CG 3.27Å; I93-E97 PolarHBondContact O-N 2.95Å
94	Y	98.3	Very high	96.5	Very high	127 Å²	127	117.6 Å²	117.6	50%	0.498	54%	0.537	S	S	.	.	H	α-helix	trans	-53.7	-50.4	-179.5	174.5	-99.2	0	0	0	112.9	K90 L91 L96 E97 E98	K90-Y94 WeakPolarHBondContact O-CB 3.47Å; K90-Y94 PolarHBondContact O-N 3.46Å; L91-Y94 PolarHBondContact O-N 3.21Å; Y94-L96 VanDerWaalsContact C-N 3.33Å; Y94-L96 PolarHBondContact O-N 3.34Å; Y94-E97 PolarHBondContact O-N 3.46Å; Y94-E98 WeakPolarHBondContact O-CB 3.45Å; Y94-E98 PolarHBondContact O-N 3.05Å
95	F	98.1	Very high	96.1	Very high	108 Å²	108	113.2 Å²	113.2	47%	0.474	52%	0.519	S	S	.	.	H	α-helix	trans	-70.2	-29.8	179.5	-66.3	-52	0	0	0	113.3	L91 I93 R99	L91-F95 HydrophobicContact CB-CE2 4.35Å; L91-F95 WeakPolarHBondContact O-CD2 3.44Å; L91-F95 PolarHBondContact O-N 3.37Å; I93-F95 PolarHBondContact O-N 3.34Å; F95-R99 WeakPolarHBondContact O-CB 3.13Å; F95-R99 VanDerWaalsContact O-CG 3.31Å; F95-R99 WeakPolarHBondContact O-CG 3.46Å; F95-R99 PolarHBondContact O-N 2.93Å; F95-R99 VanDerWaalsContact O-N 3.07Å
96	L	97.6	Very high	95.5	Very high	91 Å²	91	109.7 Å²	109.7	48%	0.476	51%	0.511	S	S	.	.	H	α-helix	trans	-68.2	-46.4	173.8	-76.3	172	0	0	0	110.9	R92 I93 Y94 R99 M100	R92-L96 HydrophobicContact CG-CD1 4.03Å; R92-L96 WeakPolarHBondContact O-CB 3.39Å; R92-L96 WeakPolarHBondContact O-CD1 3.33Å; R92-L96 WeakPolarHBondContact O-CG 3.26Å; R92-L96 PolarHBondContact O-N 3.16Å; R92-L96 VanDerWaalsContact O-N 3.09Å; I93-L96 WeakPolarHBondContact O-CB 3.44Å; I93-L96 PolarHBondContact O-N 3.13Å; I93-L96 VanDerWaalsContact O-N 3.07Å; Y94-L96 VanDerWaalsContact C-N 3.33Å; Y94-L96 PolarHBondContact O-N 3.34Å; L96-R99 PolarHBondContact O-N 2.85Å; L96-M100 WeakPolarHBondContact O-CB 3.2Å; L96-M100 WeakPolarHBondContact O-CG 3.16Å; L96-M100 PolarHBondContact O-N 2.77Å
97	E	96.5	Very high	95.2	Very high	119 Å²	119	108 Å²	108	56%	0.556	51%	0.507	S	S	*	.	H	α-helix	trans	-58.9	-47.9	175.8	-72	173.3	163.6	0	0	110.9	I93 Y94 R99 M100 Q101	I93-E97 VanDerWaalsContact CG2-CD 3.48Å; I93-E97 HydrophobicContact CG2-CG 4.1Å; I93-E97 VanDerWaalsContact CG2-OE1 3.3Å; I93-E97 WeakPolarHBondContact CG2-OE1 3.26Å; I93-E97 WeakPolarHBondContact O-CB 3.34Å; I93-E97 WeakPolarHBondContact O-CG 3.27Å; I93-E97 PolarHBondContact O-N 2.95Å; Y94-E97 PolarHBondContact O-N 3.46Å; E97-R99 PolarHBondContact O-N 3.14Å; E97-M100 PolarHBondContact O-N 3.3Å; E97-Q101 WeakPolarHBondContact O-CB 3.44Å; E97-Q101 PolarHBondContact O-N 2.71Å
98	E	96.3	Very high	94.9	Very high	81 Å²	81	106.6 Å²	106.6	38%	0.379	50%	0.498	S	S	.	.	H	α-helix	trans	-57.6	-48.5	177	-178.4	175.8	-136.1	0	0	111.9	Y94 M100 Q101 Q102	Y94-E98 WeakPolarHBondContact O-CB 3.45Å; Y94-E98 PolarHBondContact O-N 3.05Å; E98-M100 VanDerWaalsContact C-N 3.35Å; E98-M100 PolarHBondContact O-N 3.05Å; E98-Q101 PolarHBondContact O-N 3.38Å; E98-Q102 VanDerWaalsContact O-CG 3.28Å; E98-Q102 WeakPolarHBondContact O-CG 3.3Å; E98-Q102 PolarHBondContact O-N 3.36Å
99	R	95.1	Very high	94.7	Very high	152 Å²	152	107.7 Å²	107.7	57%	0.574	50%	0.495	S	S	*	.	H	α-helix	trans	-66.1	-35.2	178.4	-77.6	176.1	49.9	124.2	0.4	113.2	F95 L96 E97 K103	F95-R99 WeakPolarHBondContact O-CB 3.13Å; F95-R99 VanDerWaalsContact O-CG 3.31Å; F95-R99 WeakPolarHBondContact O-CG 3.46Å; F95-R99 PolarHBondContact O-N 2.93Å; F95-R99 VanDerWaalsContact O-N 3.07Å; L96-R99 PolarHBondContact O-N 2.85Å; E97-R99 PolarHBondContact O-N 3.14Å; R99-K103 WeakPolarHBondContact O-CG 3.26Å; R99-K103 PolarHBondContact O-N 3.49Å
100	M	94	Very high	94.5	Very high	139 Å²	139	108.6 Å²	108.6	69%	0.685	50%	0.5	S	S	*	.	H	α-helix	trans	-69.7	-42.7	176.8	-77.2	-170.6	64.5	0	0	111	L96 E97 E98 K103 Y104	L96-M100 WeakPolarHBondContact O-CB 3.2Å; L96-M100 WeakPolarHBondContact O-CG 3.16Å; L96-M100 PolarHBondContact O-N 2.77Å; E97-M100 PolarHBondContact O-N 3.3Å; E98-M100 VanDerWaalsContact C-N 3.35Å; E98-M100 PolarHBondContact O-N 3.05Å; M100-K103 PolarHBondContact O-N 3.13Å; M100-Y104 PolarHBondContact O-N 2.87Å
101	Q	93.6	Very high	94.3	Very high	105 Å²	105	106 Å²	106	49%	0.491	49%	0.493	S	S	.	.	H	α-helix	trans	-61.1	-47.2	177.1	-166.5	67.8	20.2	0	0	111.2	E97 E98 K103 Y104 E105	E97-Q101 WeakPolarHBondContact O-CB 3.44Å; E97-Q101 PolarHBondContact O-N 2.71Å; E98-Q101 PolarHBondContact O-N 3.38Å; Q101-K103 VanDerWaalsContact C-N 3.33Å; Q101-K103 PolarHBondContact O-N 2.9Å; Q101-Y104 PolarHBondContact O-N 3.07Å; Q101-Y104 VanDerWaalsContact O-N 3.16Å; Q101-E105 HydrophobicContact CG-CG 4.36Å; Q101-E105 PolarHBondContact NE2-OE1 2.84Å; Q101-E105 WeakPolarHBondContact O-CG 3.41Å; Q101-E105 PolarHBondContact O-N 3.09Å
102	Q	91.1	Very high	94.2	Very high	115 Å²	115	109.3 Å²	109.3	54%	0.537	50%	0.501	S	S	.	.	H	α-helix	trans	-56.7	-44.2	178.5	-74.2	170.7	0.4	0	0	112.7	E98 A106	E98-Q102 VanDerWaalsContact O-CG 3.28Å; E98-Q102 WeakPolarHBondContact O-CG 3.3Å; E98-Q102 PolarHBondContact O-N 3.36Å; Q102-A106 VanDerWaalsContact O-CB 3.26Å; Q102-A106 WeakPolarHBondContact O-CB 3.48Å; Q102-A106 PolarHBondContact O-N 2.87Å
103	K	90.1	Very high	94.2	Very high	146 Å²	146	107 Å²	107	64%	0.635	50%	0.496	S	S	*	.	H	α-helix	trans	-67.5	-37.7	178.3	-73.3	-177.5	177.2	-166.7	0	112.6	R99 M100 Q101 S107	R99-K103 WeakPolarHBondContact O-CG 3.26Å; R99-K103 PolarHBondContact O-N 3.49Å; M100-K103 PolarHBondContact O-N 3.13Å; Q101-K103 VanDerWaalsContact C-N 3.33Å; Q101-K103 PolarHBondContact O-N 2.9Å; K103-S107 WeakPolarHBondContact O-CB 3.35Å; K103-S107 PolarHBondContact O-N 3.45Å; K103-S107 VanDerWaalsContact O-N 3.13Å
104	Y	90.4	Very high	94.1	Very high	150 Å²	150	108.4 Å²	108.4	59%	0.588	50%	0.495	S	S	*	.	H	α-helix	trans	-69.6	-47.5	-179.6	-176.6	-98.8	0	0	0	111.5	M100 Q101 S107 R108	M100-Y104 PolarHBondContact O-N 2.87Å; Q101-Y104 PolarHBondContact O-N 3.07Å; Q101-Y104 VanDerWaalsContact O-N 3.16Å; Y104-S107 PolarHBondContact O-N 3.23Å; Y104-R108 VanDerWaalsContact O-CB 3.26Å; Y104-R108 WeakPolarHBondContact O-CB 3.31Å; Y104-R108 PolarHBondContact O-N 3.01Å
105	E	90.4	Very high	94.1	Very high	49 Å²	49	106 Å²	106	23%	0.229	49%	0.491	C	S	.	.	H	α-helix	trans	-60.6	-53.9	175.8	-62.7	-60.2	167	0	0	110.1	Q101 S107 R108 E109	Q101-E105 HydrophobicContact CG-CG 4.36Å; Q101-E105 PolarHBondContact NE2-OE1 2.84Å; Q101-E105 WeakPolarHBondContact O-CG 3.41Å; Q101-E105 PolarHBondContact O-N 3.09Å; E105-S107 VanDerWaalsContact C-N 3.28Å; E105-S107 PolarHBondContact O-N 3.45Å; E105-S107 VanDerWaalsContact O-N 3.14Å; E105-R108 CarbonylContact O-C 3.52Å; E105-R108 VanDerWaalsContact O-CA 3.3Å; E105-R108 WeakPolarHBondContact O-CA 3.45Å; E105-R108 VanDerWaalsContact O-CB 3.27Å; E105-R108 WeakPolarHBondContact O-CB 3.38Å; E105-R108 PolarHBondContact O-N 2.87Å; E105-R108 IonicContact OE1-NH2 2.71Å; E105-R108 IonicContact OE2-CZ 3.21Å; E105-R108 IonicContact OE2-NE 2.94Å; E105-R108 PolarHBondContact OE2-NE 3Å; E105-R108 IonicContact OE2-NH2 3.17Å; E105-R108 PolarHBondContact OE2-NH2 3.14Å; E105-E109 VanDerWaalsContact C-CD 3.47Å; E105-E109 PolarHBondContact O-N 2.83Å
106	A	85.3	Confident	94.2	Very high	49 Å²	49	106.2 Å²	106.2	41%	0.405	50%	0.496	S	S	.	.	H	α-helix	trans	-53.7	-44.5	-178.8	0	0	0	0	0	112.7	Q102 R108 E109 D110	Q102-A106 VanDerWaalsContact O-CB 3.26Å; Q102-A106 WeakPolarHBondContact O-CB 3.48Å; Q102-A106 PolarHBondContact O-N 2.87Å; A106-R108 VanDerWaalsContact C-N 3.33Å; A106-R108 PolarHBondContact O-N 3.07Å; A106-E109 PolarHBondContact N-OE2 3.38Å; A106-D110 PolarHBondContact O-N 3.45Å; A106-D110 VanDerWaalsContact O-N 3.12Å
107	S	91.8	Very high	94.2	Very high	63 Å²	63	105.7 Å²	105.7	44%	0.441	49%	0.491	S	S	.	.	H	α-helix	trans	-64.5	-36.5	174.5	-179	0	0	0	0	112.7	K103 Y104 E105 I111	K103-S107 WeakPolarHBondContact O-CB 3.35Å; K103-S107 PolarHBondContact O-N 3.45Å; K103-S107 VanDerWaalsContact O-N 3.13Å; Y104-S107 PolarHBondContact O-N 3.23Å; E105-S107 VanDerWaalsContact C-N 3.28Å; E105-S107 PolarHBondContact O-N 3.45Å; E105-S107 VanDerWaalsContact O-N 3.14Å; S107-I111 WeakPolarHBondContact O-CB 3.42Å; S107-I111 WeakPolarHBondContact O-CD1 3.3Å; S107-I111 WeakPolarHBondContact O-CG1 3.29Å; S107-I111 PolarHBondContact O-N 3.43Å
108	R	93	Very high	94.3	Very high	97 Å²	97	103.2 Å²	103.2	37%	0.366	48%	0.481	S	S	.	.	H	α-helix	trans	-69.1	-43.5	179.6	-165.8	176.4	72.8	167	-3.1	111.1	Y104 E105 A106 I111 Y112	Y104-R108 VanDerWaalsContact O-CB 3.26Å; Y104-R108 WeakPolarHBondContact O-CB 3.31Å; Y104-R108 PolarHBondContact O-N 3.01Å; E105-R108 CarbonylContact O-C 3.52Å; E105-R108 VanDerWaalsContact O-CA 3.3Å; E105-R108 WeakPolarHBondContact O-CA 3.45Å; E105-R108 VanDerWaalsContact O-CB 3.27Å; E105-R108 WeakPolarHBondContact O-CB 3.38Å; E105-R108 PolarHBondContact O-N 2.87Å; E105-R108 IonicContact OE1-NH2 2.71Å; E105-R108 IonicContact OE2-CZ 3.21Å; E105-R108 IonicContact OE2-NE 2.94Å; E105-R108 PolarHBondContact OE2-NE 3Å; E105-R108 IonicContact OE2-NH2 3.17Å; E105-R108 PolarHBondContact OE2-NH2 3.14Å; A106-R108 VanDerWaalsContact C-N 3.33Å; A106-R108 PolarHBondContact O-N 3.07Å; R108-I111 PolarHBondContact O-N 3.15Å; R108-Y112 HydrophobicContact CG-CD2 3.86Å; R108-Y112 HydrophobicContact CG-CE2 3.48Å; R108-Y112 VanDerWaalsContact CG-CE2 3.48Å; R108-Y112 WeakPolarHBondContact O-CD2 3.28Å; R108-Y112 PolarHBondContact O-N 3.4Å
109	E	93.6	Very high	94.4	Very high	95 Å²	95	106.5 Å²	106.5	44%	0.444	49%	0.494	S	S	.	.	H	α-helix	trans	-59.4	-45	173.6	-79.8	85.7	-117.7	0	0	111.9	E105 A106 I111 Y112 K113	E105-E109 VanDerWaalsContact C-CD 3.47Å; E105-E109 PolarHBondContact O-N 2.83Å; A106-E109 PolarHBondContact N-OE2 3.38Å; E109-I111 PolarHBondContact O-N 2.96Å; E109-Y112 PolarHBondContact O-N 3.35Å; E109-K113 WeakPolarHBondContact O-CB 3.27Å; E109-K113 PolarHBondContact O-N 3.34Å
110	D	94.8	Very high	94.6	Very high	111 Å²	111	103.8 Å²	103.8	59%	0.594	50%	0.495	S	S	*	.	H	α-helix	trans	-61.7	-43.4	177.7	-73.8	-23.3	0	0	0	111.8	A106 K113 R114	A106-D110 PolarHBondContact O-N 3.45Å; A106-D110 VanDerWaalsContact O-N 3.12Å; D110-K113 PolarHBondContact O-N 3.07Å; D110-R114 WeakPolarHBondContact O-CB 3.48Å; D110-R114 PolarHBondContact O-N 2.92Å
111	I	95.4	Very high	94.8	Very high	94 Å²	94	101.8 Å²	101.8	48%	0.482	48%	0.483	S	S	.	.	H	α-helix	trans	-62.1	-44.1	175.7	-71.5	164.4	0	0	0	110.9	S107 R108 E109 R114 N115	S107-I111 WeakPolarHBondContact O-CB 3.42Å; S107-I111 WeakPolarHBondContact O-CD1 3.3Å; S107-I111 WeakPolarHBondContact O-CG1 3.29Å; S107-I111 PolarHBondContact O-N 3.43Å; R108-I111 PolarHBondContact O-N 3.15Å; E109-I111 PolarHBondContact O-N 2.96Å; I111-R114 PolarHBondContact O-N 2.93Å; I111-N115 WeakPolarHBondContact CG2-ND2 3.32Å; I111-N115 WeakPolarHBondContact O-CB 3.48Å; I111-N115 PolarHBondContact O-N 2.78Å; I111-N115 PolarHBondContact O-ND2 3.17Å
112	Y	96.9	Very high	95	Very high	139 Å²	139	100 Å²	100	55%	0.545	48%	0.479	S	S	.	.	H	α-helix	trans	-64.2	-44.2	178.1	-80.8	-56.9	0	0	0	111.9	R108 E109 R114 N115 I116	R108-Y112 HydrophobicContact CG-CD2 3.86Å; R108-Y112 HydrophobicContact CG-CE2 3.48Å; R108-Y112 VanDerWaalsContact CG-CE2 3.48Å; R108-Y112 WeakPolarHBondContact O-CD2 3.28Å; R108-Y112 PolarHBondContact O-N 3.4Å; E109-Y112 PolarHBondContact O-N 3.35Å; Y112-R114 VanDerWaalsContact C-N 3.35Å; Y112-R114 PolarHBondContact O-N 3.4Å; Y112-N115 WeakPolarHBondContact O-CB 3.4Å; Y112-N115 PolarHBondContact O-N 2.9Å; Y112-I116 WeakPolarHBondContact O-CG1 3.49Å; Y112-I116 PolarHBondContact O-N 2.86Å
113	K	97.4	Very high	95.4	Very high	130 Å²	130	99.4 Å²	99.4	57%	0.565	48%	0.477	S	S	*	.	H	α-helix	trans	-58.9	-47.4	176.7	-173.3	-178.9	176	-173.7	0	111.1	E109 D110 N115 I116 E117	E109-K113 WeakPolarHBondContact O-CB 3.27Å; E109-K113 PolarHBondContact O-N 3.34Å; D110-K113 PolarHBondContact O-N 3.07Å; K113-N115 VanDerWaalsContact C-N 3.31Å; K113-N115 PolarHBondContact O-N 2.8Å; K113-I116 PolarHBondContact O-N 3.33Å; K113-I116 VanDerWaalsContact O-N 3.17Å; K113-E117 WeakPolarHBondContact CE-OE1 3.08Å; K113-E117 WeakPolarHBondContact O-CG 3.35Å; K113-E117 PolarHBondContact O-N 3.27Å
114	R	97.7	Very high	95.8	Very high	116 Å²	116	95.2 Å²	95.2	44%	0.438	47%	0.466	S	S	.	.	H	α-helix	trans	-63.1	-38.4	178.2	-173.9	63.3	-166.9	140.3	3.2	112.3	D110 I111 Y112 I116 E117 L118 E121	D110-R114 WeakPolarHBondContact O-CB 3.48Å; D110-R114 PolarHBondContact O-N 2.92Å; I111-R114 PolarHBondContact O-N 2.93Å; Y112-R114 VanDerWaalsContact C-N 3.35Å; Y112-R114 PolarHBondContact O-N 3.4Å; R114-I116 VanDerWaalsContact C-N 3.33Å; R114-I116 PolarHBondContact O-N 3.32Å; R114-E117 IonicContact CZ-OE2 3.95Å; R114-E117 IonicContact NH1-OE2 3.95Å; R114-E117 PolarHBondContact NH1-OE2 3.25Å; R114-E117 PolarHBondContact O-N 2.96Å; R114-L118 HydrophobicContact CG-CD1 4.06Å; R114-L118 HydrophobicContact CG-CG 4.43Å; R114-L118 WeakPolarHBondContact O-CB 3.49Å; R114-L118 VanDerWaalsContact O-CG 3.31Å; R114-L118 WeakPolarHBondContact O-CG 3.41Å; R114-L118 PolarHBondContact O-N 3.03Å; R114-E121 IonicContact NH2-OE2 2.77Å
115	N	98.1	Very high	96.2	Very high	78 Å²	78	92.5 Å²	92.5	42%	0.417	46%	0.461	S	S	.	.	H	α-helix	trans	-62.2	-40	175.1	-87.5	-60.7	0	0	0	112.5	I111 Y112 K113 K119	I111-N115 WeakPolarHBondContact CG2-ND2 3.32Å; I111-N115 WeakPolarHBondContact O-CB 3.48Å; I111-N115 PolarHBondContact O-N 2.78Å; I111-N115 PolarHBondContact O-ND2 3.17Å; Y112-N115 WeakPolarHBondContact O-CB 3.4Å; Y112-N115 PolarHBondContact O-N 2.9Å; K113-N115 VanDerWaalsContact C-N 3.31Å; K113-N115 PolarHBondContact O-N 2.8Å; N115-K119 WeakPolarHBondContact O-CB 3.46Å; N115-K119 WeakPolarHBondContact O-CG 3.38Å; N115-K119 PolarHBondContact O-N 3.44Å
116	I	98.3	Very high	96.6	Very high	111 Å²	111	95.6 Å²	95.6	57%	0.569	47%	0.474	S	S	*	.	H	α-helix	trans	-65.1	-48.6	176.4	-66.9	165.4	0	0	0	110.1	Y112 K113 R114 L118 K119 V120	Y112-I116 WeakPolarHBondContact O-CG1 3.49Å; Y112-I116 PolarHBondContact O-N 2.86Å; K113-I116 PolarHBondContact O-N 3.33Å; K113-I116 VanDerWaalsContact O-N 3.17Å; R114-I116 VanDerWaalsContact C-N 3.33Å; R114-I116 PolarHBondContact O-N 3.32Å; I116-L118 VanDerWaalsContact C-N 3.32Å; I116-L118 PolarHBondContact O-N 3.25Å; I116-K119 PolarHBondContact O-N 3.2Å; I116-K119 VanDerWaalsContact O-N 3.17Å; I116-V120 WeakPolarHBondContact O-CG2 3.43Å; I116-V120 PolarHBondContact O-N 3.46Å
117	E	98.3	Very high	97.2	Very high	81 Å²	81	101.4 Å²	101.4	38%	0.379	49%	0.485	S	S	.	.	H	α-helix	trans	-55.5	-47.6	177.1	-70	169.9	-174.2	0	0	111.6	K113 R114 K119 V120 E121	K113-E117 WeakPolarHBondContact CE-OE1 3.08Å; K113-E117 WeakPolarHBondContact O-CG 3.35Å; K113-E117 PolarHBondContact O-N 3.27Å; R114-E117 IonicContact CZ-OE2 3.95Å; R114-E117 IonicContact NH1-OE2 3.95Å; R114-E117 PolarHBondContact NH1-OE2 3.25Å; R114-E117 PolarHBondContact O-N 2.96Å; E117-K119 PolarHBondContact O-N 3.23Å; E117-V120 PolarHBondContact O-N 3.45Å; E117-E121 WeakPolarHBondContact O-CB 3.38Å; E117-E121 PolarHBondContact O-N 3.29Å
118	L	98.6	Very high	97.5	Very high	66 Å²	66	102.6 Å²	102.6	35%	0.346	48%	0.484	S	S	.	.	H	α-helix	trans	-63.2	-41.3	177.5	-76.2	171.7	0	0	0	112.3	R114 I116 V120 E121 V122	R114-L118 HydrophobicContact CG-CD1 4.06Å; R114-L118 HydrophobicContact CG-CG 4.43Å; R114-L118 WeakPolarHBondContact O-CB 3.49Å; R114-L118 VanDerWaalsContact O-CG 3.31Å; R114-L118 WeakPolarHBondContact O-CG 3.41Å; R114-L118 PolarHBondContact O-N 3.03Å; I116-L118 VanDerWaalsContact C-N 3.32Å; I116-L118 PolarHBondContact O-N 3.25Å; L118-V120 VanDerWaalsContact C-N 3.31Å; L118-V120 PolarHBondContact O-N 2.94Å; L118-E121 PolarHBondContact O-N 2.88Å; L118-V122 WeakPolarHBondContact O-CB 3.29Å; L118-V122 VanDerWaalsContact O-CG2 3.25Å; L118-V122 WeakPolarHBondContact O-CG2 3.31Å; L118-V122 PolarHBondContact O-N 2.9Å
119	K	98.6	Very high	97.7	Very high	150 Å²	150	103.7 Å²	103.7	65%	0.652	50%	0.497	S	S	*	.	H	α-helix	trans	-60.5	-43	175.2	-83.2	172.2	175.9	-81.1	0	111.2	N115 I116 E117 E123	N115-K119 WeakPolarHBondContact O-CB 3.46Å; N115-K119 WeakPolarHBondContact O-CG 3.38Å; N115-K119 PolarHBondContact O-N 3.44Å; I116-K119 PolarHBondContact O-N 3.2Å; I116-K119 VanDerWaalsContact O-N 3.17Å; E117-K119 PolarHBondContact O-N 3.23Å; K119-E123 WeakPolarHBondContact O-CG 3.43Å; K119-E123 PolarHBondContact O-N 2.77Å
120	V	98.8	Very high	97.9	Very high	96 Å²	96	104.4 Å²	104.4	58%	0.582	50%	0.5	S	S	*	.	H	α-helix	trans	-63.8	-46.4	176.9	172	0	0	0	0	110.7	I116 E117 L118 V122 E123 S124	I116-V120 WeakPolarHBondContact O-CG2 3.43Å; I116-V120 PolarHBondContact O-N 3.46Å; E117-V120 PolarHBondContact O-N 3.45Å; L118-V120 VanDerWaalsContact C-N 3.31Å; L118-V120 PolarHBondContact O-N 2.94Å; V120-V122 PolarHBondContact O-N 3.1Å; V120-E123 PolarHBondContact O-N 3.1Å; V120-S124 WeakPolarHBondContact O-CB 3.49Å; V120-S124 PolarHBondContact O-N 3.08Å
121	E	98.4	Very high	98	Very high	96 Å²	96	103.2 Å²	103.2	45%	0.449	49%	0.493	S	S	.	.	H	α-helix	trans	-60.1	-45.9	178.4	-174	173.3	-170.8	0	0	111.4	R114 E117 L118 E123 S124 L125	R114-E121 IonicContact NH2-OE2 2.77Å; E117-E121 WeakPolarHBondContact O-CB 3.38Å; E117-E121 PolarHBondContact O-N 3.29Å; L118-E121 PolarHBondContact O-N 2.88Å; E121-E123 PolarHBondContact O-N 2.9Å; E121-S124 PolarHBondContact O-N 3.35Å; E121-L125 HydrophobicContact CG-CD1 3.99Å; E121-L125 HydrophobicContact CG-CG 4.48Å; E121-L125 WeakPolarHBondContact O-CB 3.38Å; E121-L125 VanDerWaalsContact O-CG 3.25Å; E121-L125 WeakPolarHBondContact O-CG 2.98Å; E121-L125 PolarHBondContact O-N 2.96Å
122	V	98.7	Very high	98.1	Very high	67 Å²	67	105.1 Å²	105.1	41%	0.406	50%	0.498	S	S	.	.	H	α-helix	trans	-59.7	-47	176.8	166.4	0	0	0	0	111.7	L118 V120 L125 K126	L118-V122 WeakPolarHBondContact O-CB 3.29Å; L118-V122 VanDerWaalsContact O-CG2 3.25Å; L118-V122 WeakPolarHBondContact O-CG2 3.31Å; L118-V122 PolarHBondContact O-N 2.9Å; V120-V122 PolarHBondContact O-N 3.1Å; V122-L125 PolarHBondContact O-N 2.99Å; V122-K126 HydrophobicContact CG1-CD 4.21Å; V122-K126 WeakPolarHBondContact O-CB 3.46Å; V122-K126 VanDerWaalsContact O-CG 3.28Å; V122-K126 WeakPolarHBondContact O-CG 3.5Å; V122-K126 PolarHBondContact O-N 2.96Å
123	E	98.6	Very high	98.1	Very high	103 Å²	103	104.6 Å²	104.6	48%	0.481	50%	0.499	S	S	.	.	H	α-helix	trans	-68.4	-35.8	179.2	-69.1	-55.2	127.2	0	0	112.4	K119 V120 E121 K126 R127	K119-E123 WeakPolarHBondContact O-CG 3.43Å; K119-E123 PolarHBondContact O-N 2.77Å; V120-E123 PolarHBondContact O-N 3.1Å; E121-E123 PolarHBondContact O-N 2.9Å; E123-K126 IonicContact OE1-NZ 2.77Å; E123-K126 PolarHBondContact OE1-NZ 2.96Å; E123-R127 PolarHBondContact O-N 2.95Å; E123-R127 VanDerWaalsContact O-N 3.11Å
124	S	98.5	Very high	98	Very high	58 Å²	58	102.3 Å²	102.3	41%	0.406	49%	0.49	S	S	.	.	H	α-helix	trans	-61.9	-50.3	173.4	-167.3	0	0	0	0	111.3	V120 E121 K126 R127 E128	V120-S124 WeakPolarHBondContact O-CB 3.49Å; V120-S124 PolarHBondContact O-N 3.08Å; E121-S124 PolarHBondContact O-N 3.35Å; S124-K126 PolarHBondContact O-N 3.07Å; S124-R127 WeakPolarHBondContact O-CB 3.43Å; S124-R127 PolarHBondContact O-N 3.41Å; S124-R127 VanDerWaalsContact O-N 3.15Å; S124-E128 PolarHBondContact O-N 3.36Å
125	L	98.6	Very high	97.8	Very high	93 Å²	93	102.7 Å²	102.7	49%	0.487	50%	0.497	S	S	.	.	H	α-helix	trans	-64.2	-39.7	-179	-70.7	173.5	0	0	0	112.1	E121 V122 R127 E128 L129	E121-L125 HydrophobicContact CG-CD1 3.99Å; E121-L125 HydrophobicContact CG-CG 4.48Å; E121-L125 WeakPolarHBondContact O-CB 3.38Å; E121-L125 VanDerWaalsContact O-CG 3.25Å; E121-L125 WeakPolarHBondContact O-CG 2.98Å; E121-L125 PolarHBondContact O-N 2.96Å; V122-L125 PolarHBondContact O-N 2.99Å; L125-R127 VanDerWaalsContact C-N 3.31Å; L125-R127 PolarHBondContact O-N 3.05Å; L125-E128 PolarHBondContact O-N 3.35Å; L125-L129 VanDerWaalsContact O-CB 3.29Å; L125-L129 WeakPolarHBondContact O-CB 3.42Å; L125-L129 PolarHBondContact O-N 3.33Å
126	K	98.4	Very high	97.6	Very high	115 Å²	115	103.8 Å²	103.8	50%	0.5	50%	0.502	S	S	.	.	H	α-helix	trans	-58.8	-44.1	173.3	-77.8	175.3	-173.3	169.1	0	111.6	V122 E123 S124 L129 Q130	V122-K126 HydrophobicContact CG1-CD 4.21Å; V122-K126 WeakPolarHBondContact O-CB 3.46Å; V122-K126 VanDerWaalsContact O-CG 3.28Å; V122-K126 WeakPolarHBondContact O-CG 3.5Å; V122-K126 PolarHBondContact O-N 2.96Å; E123-K126 IonicContact OE1-NZ 2.77Å; E123-K126 PolarHBondContact OE1-NZ 2.96Å; S124-K126 PolarHBondContact O-N 3.07Å; K126-L129 PolarHBondContact O-N 3.32Å; K126-Q130 WeakPolarHBondContact O-CB 3.5Å; K126-Q130 PolarHBondContact O-N 2.9Å
127	R	98.3	Very high	97.4	Very high	170 Å²	170	103 Å²	103	64%	0.642	50%	0.498	S	S	*	.	H	α-helix	trans	-64.2	-48.8	178.4	-170.3	176	-61.4	174.7	2.5	111.4	E123 S124 L125 L129 Q130 D131	E123-R127 PolarHBondContact O-N 2.95Å; E123-R127 VanDerWaalsContact O-N 3.11Å; S124-R127 WeakPolarHBondContact O-CB 3.43Å; S124-R127 PolarHBondContact O-N 3.41Å; S124-R127 VanDerWaalsContact O-N 3.15Å; L125-R127 VanDerWaalsContact C-N 3.31Å; L125-R127 PolarHBondContact O-N 3.05Å; R127-L129 VanDerWaalsContact C-N 3.3Å; R127-L129 PolarHBondContact O-N 3.27Å; R127-Q130 WeakPolarHBondContact O-CB 3.49Å; R127-Q130 PolarHBondContact O-N 3.4Å; R127-D131 VanDerWaalsContact O-CG 3.26Å; R127-D131 PolarHBondContact O-N 3.33Å
128	E	98.1	Very high	97.1	Very high	88 Å²	88	105.2 Å²	105.2	41%	0.411	51%	0.507	S	S	.	.	H	α-helix	trans	-59.1	-40.6	177.1	-75.1	179.6	-141.1	0	0	112.8	S124 L125 D131 K132	S124-E128 PolarHBondContact O-N 3.36Å; L125-E128 PolarHBondContact O-N 3.35Å; E128-D131 PolarHBondContact O-N 2.99Å; E128-K132 WeakPolarHBondContact O-CB 3.37Å; E128-K132 VanDerWaalsContact O-CG 3.29Å; E128-K132 WeakPolarHBondContact O-CG 3.45Å; E128-K132 PolarHBondContact O-N 3.39Å
129	L	98.1	Very high	96.8	Very high	121 Å²	121	105.4 Å²	105.4	63%	0.634	51%	0.511	S	S	*	.	H	α-helix	trans	-66.7	-42.8	178.1	-162.7	163.1	0	0	0	110.6	L125 K126 R127 K133	L125-L129 VanDerWaalsContact O-CB 3.29Å; L125-L129 WeakPolarHBondContact O-CB 3.42Å; L125-L129 PolarHBondContact O-N 3.33Å; K126-L129 PolarHBondContact O-N 3.32Å; R127-L129 VanDerWaalsContact C-N 3.3Å; R127-L129 PolarHBondContact O-N 3.27Å; L129-K133 WeakPolarHBondContact O-CB 3.28Å; L129-K133 PolarHBondContact O-N 3.45Å
130	Q	97.9	Very high	96.1	Very high	110 Å²	110	107.4 Å²	107.4	51%	0.514	52%	0.515	S	S	.	.	H	α-helix	trans	-60.9	-46.7	174.5	179	175.5	-14.4	0	0	111.9	K126 R127 K133 Q134	K126-Q130 WeakPolarHBondContact O-CB 3.5Å; K126-Q130 PolarHBondContact O-N 2.9Å; R127-Q130 WeakPolarHBondContact O-CB 3.49Å; R127-Q130 PolarHBondContact O-N 3.4Å; Q130-K133 PolarHBondContact O-N 3.45Å; Q130-Q134 WeakPolarHBondContact O-CG 3.4Å; Q130-Q134 PolarHBondContact O-N 3.09Å
131	D	97.3	Very high	95.5	Very high	85 Å²	85	106.6 Å²	106.6	46%	0.455	52%	0.518	S	S	.	.	H	α-helix	trans	-63	-44.2	-179.6	-69.4	-16.2	0	0	0	111.3	R127 E128 K133 Q134 H135	R127-D131 VanDerWaalsContact O-CG 3.26Å; R127-D131 PolarHBondContact O-N 3.33Å; E128-D131 PolarHBondContact O-N 2.99Å; D131-K133 VanDerWaalsContact C-N 3.34Å; D131-K133 PolarHBondContact O-N 2.96Å; D131-Q134 PolarHBondContact O-N 2.97Å; D131-H135 WeakPolarHBondContact O-CB 3.45Å; D131-H135 PolarHBondContact O-N 2.77Å
132	K	96.8	Very high	94.6	Very high	134 Å²	134	108.8 Å²	108.8	58%	0.583	53%	0.533	S	S	*	.	H	α-helix	trans	-60.9	-42.1	175	-75.5	172.2	-177.5	164.7	0	111.9	E128 H135 L136	E128-K132 WeakPolarHBondContact O-CB 3.37Å; E128-K132 VanDerWaalsContact O-CG 3.29Å; E128-K132 WeakPolarHBondContact O-CG 3.45Å; E128-K132 PolarHBondContact O-N 3.39Å; K132-H135 PolarHBondContact O-N 2.98Å; K132-L136 WeakPolarHBondContact O-CG 3.28Å; K132-L136 PolarHBondContact O-N 2.96Å
133	K	96.1	Very high	92.9	Very high	128 Å²	128	113.5 Å²	113.5	56%	0.557	56%	0.561	S	S	*	*	H	α-helix	trans	-63.7	-46.6	177	-174.8	174.3	179.3	179	0	111.6	L129 Q130 D131 H135 L136 D137	L129-K133 WeakPolarHBondContact O-CB 3.28Å; L129-K133 PolarHBondContact O-N 3.45Å; Q130-K133 PolarHBondContact O-N 3.45Å; D131-K133 VanDerWaalsContact C-N 3.34Å; D131-K133 PolarHBondContact O-N 2.96Å; K133-H135 VanDerWaalsContact C-N 3.29Å; K133-H135 PolarHBondContact O-N 2.96Å; K133-L136 PolarHBondContact O-N 3.47Å; K133-D137 VanDerWaalsContact O-CG 3.26Å; K133-D137 PolarHBondContact O-N 2.94Å
134	Q	95.3	Very high	92.6	Very high	82 Å²	82	114 Å²	114	38%	0.383	57%	0.565	S	S	.	*	H	α-helix	trans	-61.9	-38	176.7	-71.8	-179.1	7.7	0	0	112.5	Q130 D131 D137 K138	Q130-Q134 WeakPolarHBondContact O-CG 3.4Å; Q130-Q134 PolarHBondContact O-N 3.09Å; D131-Q134 PolarHBondContact O-N 2.97Å; Q134-D137 PolarHBondContact O-N 3.45Å; Q134-K138 VanDerWaalsContact O-CG 3.28Å; Q134-K138 WeakPolarHBondContact O-CG 3.28Å; Q134-K138 PolarHBondContact O-N 3.27Å
135	H	94.4	Very high	92.3	Very high	125 Å²	125	116.9 Å²	116.9	58%	0.579	57%	0.573	S	S	*	*	H	α-helix	trans	-64.6	-45	176.4	-166.7	-55.9	0	0	0	111.3	D131 K132 K133 K138 T139	D131-H135 WeakPolarHBondContact O-CB 3.45Å; D131-H135 PolarHBondContact O-N 2.77Å; K132-H135 PolarHBondContact O-N 2.98Å; K133-H135 VanDerWaalsContact C-N 3.29Å; K133-H135 PolarHBondContact O-N 2.96Å; H135-K138 PolarHBondContact O-N 3.08Å; H135-T139 PolarHBondContact ND1-OG1 3.29Å; H135-T139 PolarHBondContact O-N 2.91Å; H135-T139 PolarHBondContact O-OG1 3.23Å
136	L	93.4	Very high	91.9	Very high	101 Å²	101	118.3 Å²	118.3	53%	0.529	58%	0.578	S	S	.	*	H	α-helix	trans	-59.4	-49.3	174.7	-74.3	166.9	0	0	0	111	K132 K133 K138 T139 W140	K132-L136 WeakPolarHBondContact O-CG 3.28Å; K132-L136 PolarHBondContact O-N 2.96Å; K133-L136 PolarHBondContact O-N 3.47Å; L136-K138 VanDerWaalsContact C-N 3.28Å; L136-K138 PolarHBondContact O-N 3.49Å; L136-T139 PolarHBondContact O-N 3.24Å; L136-T139 VanDerWaalsContact O-N 3.15Å; L136-W140 PolarHBondContact O-N 3.35Å
137	D	93.7	Very high	91.5	Very high	93 Å²	93	118.5 Å²	118.5	50%	0.497	58%	0.583	S	S	.	*	H	α-helix	trans	-58.6	-39	-179.1	-68.4	-18.5	0	0	0	112	K133 Q134 A141	K133-D137 VanDerWaalsContact O-CG 3.26Å; K133-D137 PolarHBondContact O-N 2.94Å; Q134-D137 PolarHBondContact O-N 3.45Å; D137-A141 WeakPolarHBondContact O-CB 3.39Å; D137-A141 PolarHBondContact O-N 3.26Å; D137-A141 VanDerWaalsContact O-N 3.08Å
138	K	92.4	Very high	91.1	Very high	129 Å²	129	115.3 Å²	115.3	56%	0.561	58%	0.579	S	S	*	*	H	α-helix	trans	-65.2	-50.2	173.7	-71.6	168.2	-174.4	173.4	0	111.8	Q134 H135 L136 W140 A141 D142	Q134-K138 VanDerWaalsContact O-CG 3.28Å; Q134-K138 WeakPolarHBondContact O-CG 3.28Å; Q134-K138 PolarHBondContact O-N 3.27Å; H135-K138 PolarHBondContact O-N 3.08Å; L136-K138 VanDerWaalsContact C-N 3.28Å; L136-K138 PolarHBondContact O-N 3.49Å; K138-W140 VanDerWaalsContact C-N 3.25Å; K138-W140 PolarHBondContact O-N 3.44Å; K138-A141 PolarHBondContact O-N 3.3Å; K138-D142 PolarHBondContact O-N 3.41Å; K138-D142 VanDerWaalsContact O-N 3.09Å
139	T	91.9	Very high	90.7	Very high	70 Å²	70	117.1 Å²	117.1	43%	0.429	59%	0.59	S	S	.	*	H	α-helix	trans	-60.8	-35.1	179.3	-54	0	0	0	0	112.2	H135 L136 V143	H135-T139 PolarHBondContact ND1-OG1 3.29Å; H135-T139 PolarHBondContact O-N 2.91Å; H135-T139 PolarHBondContact O-OG1 3.23Å; L136-T139 PolarHBondContact O-N 3.24Å; L136-T139 VanDerWaalsContact O-N 3.15Å; T139-V143 WeakPolarHBondContact O-CG2 3.43Å
140	W	85	Confident	90.1	Very high	192 Å²	192	116.8 Å²	116.8	73%	0.727	59%	0.587	S	S	*	*	H	α-helix	trans	-72.8	-27.6	174	-77.4	114.4	0	0	0	113.8	L136 K138	L136-W140 PolarHBondContact O-N 3.35Å; K138-W140 VanDerWaalsContact C-N 3.25Å; K138-W140 PolarHBondContact O-N 3.44Å
141	A	85.2	Confident	89.5	Confident	78 Å²	78	117.3 Å²	117.3	65%	0.645	59%	0.593	S	S	*	*	H	α-helix	trans	-78.8	-23.2	176.9	0	0	0	0	0	113	D137 K138	D137-A141 WeakPolarHBondContact O-CB 3.39Å; D137-A141 PolarHBondContact O-N 3.26Å; D137-A141 VanDerWaalsContact O-N 3.08Å; K138-A141 PolarHBondContact O-N 3.3Å
142	D	80	Confident	88.9	Confident	142 Å²	142	120 Å²	120	76%	0.759	61%	0.605	S	S	*	*			trans	-87.1	-0.9	179.7	-65.2	-30.9	0	0	0	113.7	K138	K138-D142 PolarHBondContact O-N 3.41Å; K138-D142 VanDerWaalsContact O-N 3.09Å
143	V	62.4	Low	88.2	Confident	166 Å²	166	118.7 Å²	118.7	100%	1.006	61%	0.607	S	S	*	*			trans	-105.9	0	177.4	174	0	0	0	0	110.5	T139	T139-V143 WeakPolarHBondContact O-CG2 3.43Å

Retrieved 143 of 143 residues in 22.4 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).