A0A087WWQ3_HUMAN Loading...

Heat shock transcription factor 1

AlphaFold DB , UniProt , Accession A0A087WWQ3, Species HUMAN (Homo sapiens, Human), Gene HSF1, Length 47 aa.

						>A0A087WWQ3_HUMAN|A0A087WWQ3|HSF1
IISDITELAPASPMASPGGSIDESPHGRQGPHGHRGPASLPPAHLHP
					

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	I	62.3	Low	69.6	Low	213 Å²	213	139.8 Å²	139.8	100%	1.092	81%	0.809	S	S	*	*				0	104.5	0	-61.1	167.1	0	0	0	105.1
2	I	61.3	Low	70.1	Confident	153 Å²	153	137.4 Å²	137.4	79%	0.785	81%	0.807	S	S	*	*			trans	-82.3	120.4	179	-64.8	170.2	0	0	0	105.4	D4	I2-D4 PolarHBondContact O-N 3.06Å
3	S	59.3	Low	70.1	Confident	100 Å²	100	136.6 Å²	136.6	70%	0.699	81%	0.808	S	S	*	*			trans	-72.3	104.5	174.3	-63.5	0	0	0	0	107.6	I5	S3-I5 WeakPolarHBondContact O-CG1 3.44Å; S3-I5 PolarHBondContact O-N 2.92Å
4	D	73	Confident	70.5	Confident	145 Å²	145	139.9 Å²	139.9	78%	0.775	82%	0.815	S	S	*	*			trans	-63.7	98	172.2	-72.4	-24.5	0	0	0	108.5	I2 T6	I2-D4 PolarHBondContact O-N 3.06Å; D4-T6 PolarHBondContact O-N 3.47Å; D4-T6 VanDerWaalsContact O-N 3.14Å
5	I	70.3	Confident	70.5	Confident	152 Å²	152	136.7 Å²	136.7	78%	0.779	81%	0.811	S	S	*	*			trans	-78.6	96.7	171.8	-39.4	176.8	0	0	0	105	S3 E7	S3-I5 WeakPolarHBondContact O-CG1 3.44Å; S3-I5 PolarHBondContact O-N 2.92Å; I5-E7 PolarHBondContact O-N 3.2Å
6	T	70.2	Confident	70.3	Confident	113 Å²	113	134.7 Å²	134.7	69%	0.693	81%	0.806	S	S	*	*			trans	-65.7	109	175.4	44.8	0	0	0	0	108.4	D4 L8	D4-T6 PolarHBondContact O-N 3.47Å; D4-T6 VanDerWaalsContact O-N 3.14Å; T6-L8 PolarHBondContact O-N 3.32Å
7	E	72.9	Confident	69.8	Low	191 Å²	191	134.2 Å²	134.2	89%	0.893	81%	0.807	S	S	*	*			trans	-66	107.5	170.1	-66.1	-161.4	152.8	0	0	108.3	I5 A9	I5-E7 PolarHBondContact O-N 3.2Å; E7-A9 PolarHBondContact O-N 3.14Å
8	L	72.9	Confident	69.4	Low	161 Å²	161	131.2 Å²	131.2	84%	0.843	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-75.2	123.8	175.1	-75.3	164.9	0	0	0	108.7	T6	T6-L8 PolarHBondContact O-N 3.32Å
9	A	76.2	Confident	69.3	Low	87 Å²	87	128.2 Å²	128.2	72%	0.719	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-59.6	151.9	177.5	0	0	0	0	0	111.4	E7 A11	E7-A9 PolarHBondContact O-N 3.14Å; A9-A11 PolarHBondContact O-N 3.24Å
10	P	72.8	Confident	69.1	Low	123 Å²	123	127.5 Å²	127.5	80%	0.799	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-61.7	124.2	-179.5	-14.2	25.4	0	0	0	111	S12	P10-S12 PolarHBondContact O-N 3.05Å
11	A	74.6	Confident	69	Low	100 Å²	100	129.3 Å²	129.3	83%	0.826	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-70.6	120.4	172.7	0	0	0	0	0	109.4	A9	A9-A11 PolarHBondContact O-N 3.24Å
12	S	74.9	Confident	69	Low	111 Å²	111	126.7 Å²	126.7	78%	0.776	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-74.2	138.3	172	-65.1	0	0	0	0	109.8	P10 M14	P10-S12 PolarHBondContact O-N 3.05Å; S12-M14 PolarHBondContact O-N 3.25Å
13	P	70.4	Confident	69.1	Low	127 Å²	127	126.5 Å²	126.5	83%	0.825	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-64.5	125	175	25.3	-30.6	0	0	0	109.2	A15	P13-A15 PolarHBondContact O-N 3.06Å
14	M	75.6	Confident	69	Low	183 Å²	183	124.5 Å²	124.5	90%	0.901	78%	0.777	S	S	*	*	P	Polyproline II helix	trans	-62.8	116.8	177	-164	156.9	68.1	0	0	108.4	S12 S16	S12-M14 PolarHBondContact O-N 3.25Å; M14-S16 PolarHBondContact O-N 3.18Å
15	A	70.1	Confident	68.5	Low	91 Å²	91	123 Å²	123	75%	0.752	78%	0.776	S	S	*	*			trans	-60.2	115.4	172.8	0	0	0	0	0	108.2	P13	P13-A15 PolarHBondContact O-N 3.06Å
16	S	67.7	Low	67.8	Low	105 Å²	105	124 Å²	124	73%	0.734	78%	0.776	S	S	*	*			trans	-60.9	132.1	173.3	-167.3	0	0	0	0	108.2	M14 G18	M14-S16 PolarHBondContact O-N 3.18Å; S16-G18 PolarHBondContact O-N 2.75Å
17	P	62.6	Low	67	Low	127 Å²	127	120.9 Å²	120.9	83%	0.825	77%	0.767	S	S	*	*			trans	-67.6	88.8	171.7	-8.8	24.2	0	0	0	107.3	G19	P17-G19 PolarHBondContact O-N 3.44Å
18	G	62.9	Low	66.6	Low	79 Å²	79	123.1 Å²	123.1	81%	0.814	77%	0.767	S	S	*	*			trans	-69.3	75	173.4	0	0	0	0	0	109.3	S16	S16-G18 PolarHBondContact O-N 2.75Å
19	G	65.9	Low	65.9	Low	75 Å²	75	125.1 Å²	125.1	77%	0.773	77%	0.772	S	S	*	*			trans	-83.2	104.4	164.1	0	0	0	0	0	108.9	P17	P17-G19 PolarHBondContact O-N 3.44Å
20	S	66.8	Low	65.1	Low	113 Å²	113	124 Å²	124	79%	0.79	77%	0.77	S	S	*	*			trans	-138.7	96.7	151.9	63.9	0	0	0	0	108.2	D22	S20-D22 PolarHBondContact O-N 2.8Å
21	I	65.7	Low	64.9	Low	166 Å²	166	124.6 Å²	124.6	85%	0.851	77%	0.773	S	S	*	*			trans	-60.5	120.6	157.8	6	171.3	0	0	0	107.2
22	D	63.4	Low	63.9	Low	158 Å²	158	128.6 Å²	128.6	85%	0.845	77%	0.774	S	S	*	*			trans	-141.3	81.1	143.6	-168.2	56.2	0	0	0	107	S20	S20-D22 PolarHBondContact O-N 2.8Å
23	E	62.2	Low	62.9	Low	150 Å²	150	125.6 Å²	125.6	70%	0.701	76%	0.761	S	S	*	*			trans	-89.2	127.6	168.9	-176.3	-108.8	121.4	0	0	108.2
24	S	59	Low	62.1	Low	57 Å²	57	128 Å²	128	40%	0.399	76%	0.761	S	S	.	*			trans	81.9	122.9	161.5	-91.9	0	0	0	0	120.6	G27	S24-G27 WeakPolarHBondContact OG-CA 3.41Å; S24-G27 PolarHBondContact OG-N 3.02Å
25	P	60.4	Low	61.2	Low	115 Å²	115	131.4 Å²	131.4	75%	0.747	76%	0.763	S	S	*	*	S	Bend	trans	-90.7	-8.9	138.2	29.1	-25	0	0	0	113.5
26	H	57.5	Low	60.2	Low	171 Å²	171	130.2 Å²	130.2	79%	0.792	76%	0.76	S	S	*	*	S	Bend	trans	-133.9	21.4	-167.3	-59.5	-44.8	0	0	0	116.4	R28	H26-R28 PolarHBondContact O-N 3.15Å; H26-R28 VanDerWaalsContact O-N 3.15Å
27	G	53.5	Low	59.5	Low	49 Å²	49	131.1 Å²	131.1	51%	0.505	76%	0.763	S	S	.	*			trans	-81.9	83.3	174.1	0	0	0	0	0	113.1	S24	S24-G27 WeakPolarHBondContact OG-CA 3.41Å; S24-G27 PolarHBondContact OG-N 3.02Å
28	R	62.5	Low	59.5	Low	238 Å²	238	130.3 Å²	130.3	90%	0.898	77%	0.767	S	S	*	*			trans	30.9	100.6	153.2	-66.7	-174.8	173.3	-150.2	-0.8	117.6	H26	H26-R28 PolarHBondContact O-N 3.15Å; H26-R28 VanDerWaalsContact O-N 3.15Å
29	Q	58.2	Low	59.3	Low	203 Å²	203	131.6 Å²	131.6	95%	0.949	76%	0.764	S	S	*	*			trans	-92.4	103.7	145.8	-66.2	-160.4	20.9	0	0	109.1
30	G	60.3	Low	59	Low	64 Å²	64	135.8 Å²	135.8	66%	0.66	77%	0.768	S	S	*	*			trans	-70.9	-174.7	167.7	0	0	0	0	0	112.6
31	P	69.5	Low	58.4	Low	134 Å²	134	135.8 Å²	135.8	87%	0.87	77%	0.765	S	S	*	*			trans	-83.2	141.7	-147.8	33.3	-34	0	0	0	113.2
32	H	53.4	Low	57.9	Low	185 Å²	185	132.7 Å²	132.7	86%	0.856	76%	0.756	S	S	*	*				143.9	126.1	120.5	-167.2	74.7	0	0	0	115.1
33	G	53.9	Low	57.8	Low	47 Å²	47	129.9 Å²	129.9	49%	0.485	75%	0.754	S	S	.	*			trans	89.1	142.5	156.9	0	0	0	0	0	114.2
34	H	53.8	Low	57.7	Low	178 Å²	178	131.3 Å²	131.3	82%	0.824	76%	0.76	S	S	*	*			cis	-164.2	125.3	19.1	3.9	-84.9	0	0	0	109.1
35	R	54.9	Low	57.8	Low	255 Å²	255	137 Å²	137	96%	0.962	79%	0.785	S	S	*	*			trans	11.5	118.2	156.6	-174.2	-176.6	-94.2	173.3	-8.1	118.8
36	G	50.2	Low	57	Low	66 Å²	66	140 Å²	140	68%	0.68	79%	0.789	S	S	*	*			trans	-133.4	150.4	151.5	0	0	0	0	0	110.1
37	P	52.8	Low	57.2	Low	124 Å²	124	140.5 Å²	140.5	81%	0.805	81%	0.808	S	S	*	*			trans	-78.4	152.6	-153.5	32.4	-34.9	0	0	0	114.8
38	A	61.6	Low	57.4	Low	110 Å²	110	145.1 Å²	145.1	91%	0.909	82%	0.823	S	S	*	*			trans	-44.1	137.5	179.7	0	0	0	0	0	115.6
39	S	60.6	Low	57.1	Low	106 Å²	106	140.2 Å²	140.2	74%	0.741	82%	0.819	S	S	*	*			trans	-152.8	122.1	167.7	6.4	0	0	0	0	106.7
40	L	58.9	Low	57	Low	162 Å²	162	136.7 Å²	136.7	85%	0.848	81%	0.812	S	S	*	*			cis	-156	163.5	18.4	-76.1	165.1	0	0	0	110.2
41	P	55	Low	56.9	Low	114 Å²	114	141 Å²	141	74%	0.74	82%	0.821	S	S	*	*			trans	-92.2	-168.8	177	40.1	-35.5	0	0	0	112.4
42	P	54.4	Low	56.1	Low	101 Å²	101	141.4 Å²	141.4	66%	0.656	82%	0.818	S	S	*	*				-97.8	160.1	-71	36.1	-24.3	0	0	0	111.9	H44	P42-H44 PolarHBondContact O-N 3.08Å
43	A	60.3	Low	56.2	Low	98 Å²	98	138.5 Å²	138.5	81%	0.81	82%	0.815	S	S	*	*			trans	-61.8	120.1	174.2	0	0	0	0	0	111.1	L45	A43-L45 PolarHBondContact O-N 3.25Å; A43-L45 VanDerWaalsContact O-N 3.08Å
44	H	60.7	Low	56.4	Low	180 Å²	180	145.1 Å²	145.1	83%	0.833	84%	0.839	S	S	*	*			trans	-69.1	101.9	167.8	-63.5	-72.5	0	0	0	108.7	P42	P42-H44 PolarHBondContact O-N 3.08Å
45	L	62.3	Low	56.6	Low	176 Å²	176	142.5 Å²	142.5	92%	0.921	84%	0.84	S	S	*	*			trans	-66	127.4	160	-76.4	163.6	0	0	0	107.7	A43	A43-L45 PolarHBondContact O-N 3.25Å; A43-L45 VanDerWaalsContact O-N 3.08Å
46	H	42.3	Very low	56.7	Low	179 Å²	179	133.2 Å²	133.2	83%	0.829	83%	0.83	S	S	*	*			trans	-128	149.4	-179.6	-162.1	-115.6	0	0	0	108.8
47	P	61.9	Low	57.3	Low	182 Å²	182	139.3 Å²	139.3	100%	1.182	84%	0.843	S	S	*	*				-68.7	0	-99	33	-39.6	0	0	0	115.6

Retrieved 47 of 47 residues in 32.9 ms (Link to these results)

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