A0A087WWQ9_HUMAN Loading...

Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

AlphaFold DB , UniProt , Accession A0A087WWQ9, Species HUMAN (Homo sapiens, Human), Gene IKBKG, Length 48 aa.

						>A0A087WWQ9_HUMAN|A0A087WWQ9|IKBKG
MALVIQVGKLRPREVRTPQTINPSLFPSLPVKLSSIIEVPSALALLDE
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	41.1	Very low	69.7	Low	255 Å²	255	155.8 Å²	155.8	100%	1.256	82%	0.821	S	S	*	*				0	133	0	-78.7	175.9	146.4	0	0	108
2	A	67.8	Low	70.4	Confident	95 Å²	95	153.7 Å²	153.7	79%	0.785	82%	0.823	S	S	*	*			trans	-120.7	129.4	-179.2	0	0	0	0	0	109.8
3	L	71.3	Confident	70.9	Confident	158 Å²	158	159.5 Å²	159.5	83%	0.827	83%	0.826	S	S	*	*			trans	-84.2	113.4	176.9	-177.2	65.9	0	0	0	108.7	I5	L3-I5 HydrophobicContact CG-CG1 4.47Å
4	V	71.1	Confident	71.3	Confident	123 Å²	123	160.4 Å²	160.4	75%	0.745	83%	0.825	S	S	*	*			trans	-92.8	110.4	177.7	-178.9	0	0	0	0	108.6
5	I	75.3	Confident	71.7	Confident	133 Å²	133	157.7 Å²	157.7	68%	0.682	82%	0.818	S	S	*	*			trans	-88.4	111.5	175.8	-57.8	175.3	0	0	0	107.9	L3 V7	L3-I5 HydrophobicContact CG-CG1 4.47Å; I5-V7 PolarHBondContact O-N 3.16Å; I5-V7 VanDerWaalsContact O-N 3.16Å
6	Q	73.4	Confident	71.8	Confident	183 Å²	183	162.1 Å²	162.1	86%	0.855	82%	0.82	S	S	*	*			trans	-72.6	105.4	171.4	-72.6	-174.6	31.5	0	0	109.2	G8	Q6-G8 PolarHBondContact O-N 3.17Å
7	V	71.9	Confident	72.1	Confident	115 Å²	115	159.3 Å²	159.3	70%	0.697	81%	0.814	S	S	*	*			trans	-76.3	102.6	171.3	-167.6	0	0	0	0	107	I5 L10	I5-V7 PolarHBondContact O-N 3.16Å; I5-V7 VanDerWaalsContact O-N 3.16Å; V7-L10 HydrophobicContact CG1-CD1 4.32Å; V7-L10 HydrophobicContact CG1-CG 4.46Å
8	G	75.5	Confident	72.2	Confident	57 Å²	57	157.2 Å²	157.2	59%	0.588	81%	0.812	S	S	*	*			trans	-56.7	158.6	174.7	0	0	0	0	0	111.7	Q6 L10	Q6-G8 PolarHBondContact O-N 3.17Å; G8-L10 PolarHBondContact O-N 2.9Å
9	K	73.5	Confident	72.4	Confident	213 Å²	213	158.6 Å²	158.6	93%	0.926	82%	0.815	S	S	*	*			trans	-54.9	107.4	-177.3	-67	-175.2	179.3	179.7	0	110.8	R11	K9-R11 PolarHBondContact O-N 3.15Å
10	L	70	Confident	72.2	Confident	153 Å²	153	157.5 Å²	157.5	80%	0.801	82%	0.816	S	S	*	*			trans	-66	113.1	173.5	-72.3	164.6	0	0	0	108	V7 G8	V7-L10 HydrophobicContact CG1-CD1 4.32Å; V7-L10 HydrophobicContact CG1-CG 4.46Å; G8-L10 PolarHBondContact O-N 2.9Å
11	R	76.4	Confident	72.1	Confident	229 Å²	229	156.1 Å²	156.1	86%	0.864	81%	0.808	S	S	*	*	P	Polyproline II helix	trans	-74.2	139	173.1	-64	-175.6	-175.6	-174.2	1	108.5	K9 R13	K9-R11 PolarHBondContact O-N 3.15Å; R11-R13 PolarHBondContact O-N 3.19Å; R11-R13 VanDerWaalsContact O-N 3.15Å
12	P	77.5	Confident	73.2	Confident	130 Å²	130	148.3 Å²	148.3	84%	0.844	77%	0.772	S	S	*	*	P	Polyproline II helix	trans	-53.5	123.5	170.2	-24.5	34	0	0	0	109.3	E14	P12-E14 PolarHBondContact O-N 3.13Å
13	R	77.3	Confident	72.9	Confident	229 Å²	229	148.2 Å²	148.2	86%	0.864	76%	0.763	S	S	*	*	P	Polyproline II helix	trans	-68.4	119.7	176.5	-178	171.5	178.2	139.3	-2.8	107.6	R11 V15	R11-R13 PolarHBondContact O-N 3.19Å; R11-R13 VanDerWaalsContact O-N 3.15Å; R13-V15 PolarHBondContact O-N 3.49Å; R13-V15 VanDerWaalsContact O-N 3.08Å
14	E	75.9	Confident	72.4	Confident	173 Å²	173	144.9 Å²	144.9	81%	0.808	75%	0.753	S	S	*	*			trans	-64	111.1	172.3	-168.9	179.8	168.1	0	0	108.4	P12 R16	P12-E14 PolarHBondContact O-N 3.13Å; E14-R16 PolarHBondContact O-N 3.08Å
15	V	77.4	Confident	71.8	Confident	119 Å²	119	144.6 Å²	144.6	72%	0.721	75%	0.747	S	S	*	*			trans	-87.6	107.5	175.8	-179.5	0	0	0	0	106.7	R13 T17	R13-V15 PolarHBondContact O-N 3.49Å; R13-V15 VanDerWaalsContact O-N 3.08Å; V15-T17 PolarHBondContact O-N 3.29Å; V15-T17 VanDerWaalsContact O-N 3.13Å
16	R	73	Confident	71.3	Confident	228 Å²	228	145.9 Å²	145.9	86%	0.86	75%	0.747	S	S	*	*			trans	-63.8	114.3	170	-79.9	-174.2	177.5	178.7	-0.7	108.5	E14	E14-R16 PolarHBondContact O-N 3.08Å
17	T	77.1	Confident	70.8	Confident	115 Å²	115	141.8 Å²	141.8	71%	0.706	74%	0.737	S	S	*	*	P	Polyproline II helix	trans	-66.4	129.3	170.7	50.1	0	0	0	0	108.8	V15 Q19	V15-T17 PolarHBondContact O-N 3.29Å; V15-T17 VanDerWaalsContact O-N 3.13Å; T17-Q19 PolarHBondContact O-N 3.22Å
18	P	74.7	Confident	70.6	Confident	122 Å²	122	141.9 Å²	141.9	79%	0.792	74%	0.743	S	S	*	*	P	Polyproline II helix	trans	-57.9	128.5	170	22.2	-28.8	0	0	0	108.4	T20	P18-T20 PolarHBondContact O-N 3.25Å
19	Q	74.8	Confident	70	Confident	184 Å²	184	145.5 Å²	145.5	86%	0.86	75%	0.748	S	S	*	*	P	Polyproline II helix	trans	-66.9	118.6	178.3	-68.6	178.5	-18	0	0	108.2	T17 I21	T17-Q19 PolarHBondContact O-N 3.22Å; Q19-I21 PolarHBondContact O-N 3.05Å
20	T	69	Low	69.5	Low	136 Å²	136	141.3 Å²	141.3	83%	0.834	74%	0.742	S	S	*	*			trans	-62.8	109.3	171.3	-55.3	0	0	0	0	108.2	P18 N22	P18-T20 PolarHBondContact O-N 3.25Å; T20-N22 PolarHBondContact O-N 3.36Å
21	I	71.1	Confident	69.1	Low	128 Å²	128	138.6 Å²	138.6	66%	0.656	73%	0.732	S	S	*	*			trans	-64.2	125.9	172.5	-60.4	174.8	0	0	0	106.8	Q19 L25	Q19-I21 PolarHBondContact O-N 3.05Å; I21-L25 HydrophobicContact CG2-CB 4.27Å; I21-L25 HydrophobicContact CG2-CD1 3.44Å; I21-L25 VanDerWaalsContact CG2-CD1 3.44Å; I21-L25 HydrophobicContact CG2-CG 4.47Å
22	N	63.9	Low	68.5	Low	91 Å²	91	135.4 Å²	135.4	49%	0.487	72%	0.724	S	S	.	*			trans	-56.5	128	-176.8	-170.7	-21.9	0	0	0	109.8	T20 S24 L25	T20-N22 PolarHBondContact O-N 3.36Å; N22-S24 PolarHBondContact ND2-OG 3.14Å; N22-S24 PolarHBondContact O-N 2.8Å; N22-S24 WeakPolarHBondContact OD1-CB 3.21Å; N22-S24 PolarHBondContact OD1-N 2.95Å; N22-S24 PolarHBondContact OD1-OG 3.28Å; N22-L25 PolarHBondContact O-N 3.23Å; N22-L25 WeakPolarHBondContact O-CB 3.39Å
23	P	60.6	Low	67.7	Low	94 Å²	94	135.6 Å²	135.6	61%	0.61	72%	0.717	S	S	*	*	G	3₁₀ helix	trans	-59.9	-14.9	177.3	24	-34.8	0	0	0	113.2	L25 F26	P23-L25 PolarHBondContact O-N 2.95Å; P23-F26 WeakPolarHBondContact O-CD2 3.37Å; P23-F26 PolarHBondContact O-N 3.01Å
24	S	61.8	Low	66.8	Low	87 Å²	87	129.2 Å²	129.2	61%	0.608	71%	0.708	S	S	*	*	G	3₁₀ helix	trans	-67.7	-10	171.4	77.7	0	0	0	0	114.2	N22 F26	N22-S24 PolarHBondContact ND2-OG 3.14Å; N22-S24 PolarHBondContact O-N 2.8Å; N22-S24 WeakPolarHBondContact OD1-CB 3.21Å; N22-S24 PolarHBondContact OD1-N 2.95Å; N22-S24 PolarHBondContact OD1-OG 3.28Å; S24-F26 VanDerWaalsContact C-N 3.3Å
25	L	58.7	Low	65.9	Low	117 Å²	117	125.5 Å²	125.5	61%	0.613	70%	0.701	S	S	*	*	G	3₁₀ helix	trans	-84.9	-3	175.8	-72.1	167	0	0	0	113.2	I21 N22 P23 P27	I21-L25 HydrophobicContact CG2-CB 4.27Å; I21-L25 HydrophobicContact CG2-CD1 3.44Å; I21-L25 VanDerWaalsContact CG2-CD1 3.44Å; I21-L25 HydrophobicContact CG2-CG 4.47Å; N22-L25 PolarHBondContact O-N 3.23Å; N22-L25 WeakPolarHBondContact O-CB 3.39Å; P23-L25 PolarHBondContact O-N 2.95Å; L25-P27 WeakPolarHBondContact O-CD 3.46Å
26	F	64.6	Low	65.1	Low	160 Å²	160	125 Å²	125	70%	0.702	69%	0.693	S	S	*	*	S	Bend	trans	-80.9	103.6	163	-65.3	-76.7	0	0	0	107.1	P23 S24 S28	P23-F26 WeakPolarHBondContact O-CD2 3.37Å; P23-F26 PolarHBondContact O-N 3.01Å; S24-F26 VanDerWaalsContact C-N 3.3Å; F26-S28 PolarHBondContact O-N 3.06Å; F26-S28 VanDerWaalsContact O-N 3.14Å
27	P	62.6	Low	64.5	Low	98 Å²	98	120.1 Å²	120.1	64%	0.636	68%	0.683	S	S	*	*			trans	-54.3	129.5	164.5	25	-32.3	0	0	0	106	L25 L29	L25-P27 WeakPolarHBondContact O-CD 3.46Å; P27-L29 HydrophobicContact CG-CG 4.42Å; P27-L29 PolarHBondContact O-N 3.23Å
28	S	66.6	Low	63.8	Low	116 Å²	116	123.4 Å²	123.4	81%	0.811	69%	0.69	S	S	*	*			trans	-62.5	81.3	168.6	56.7	0	0	0	0	106.9	F26 P30	F26-S28 PolarHBondContact O-N 3.06Å; F26-S28 VanDerWaalsContact O-N 3.14Å; S28-P30 WeakPolarHBondContact O-CD 3.26Å; S28-P30 VanDerWaalsContact O-N 3.15Å
29	L	63.3	Low	63.3	Low	134 Å²	134	122.9 Å²	122.9	70%	0.702	69%	0.685	S	S	*	*			trans	-61.2	117.4	174	-81.6	162.5	0	0	0	105.2	P27 V31	P27-L29 HydrophobicContact CG-CG 4.42Å; P27-L29 PolarHBondContact O-N 3.23Å; L29-V31 PolarHBondContact O-N 3.35Å
30	P	62.5	Low	62.3	Low	124 Å²	124	119.2 Å²	119.2	81%	0.805	68%	0.677	S	S	*	*			trans	-68.4	92.8	172	27.6	-29.8	0	0	0	106.4	S28 K32	S28-P30 WeakPolarHBondContact O-CD 3.26Å; S28-P30 VanDerWaalsContact O-N 3.15Å; P30-K32 PolarHBondContact O-N 3.43Å
31	V	62.7	Low	61.8	Low	96 Å²	96	118.2 Å²	118.2	58%	0.582	68%	0.675	S	S	*	*			trans	-67.8	104.3	174	-170.7	0	0	0	0	105.9	L29 L33 I36	L29-V31 PolarHBondContact O-N 3.35Å; V31-L33 PolarHBondContact O-N 3.18Å; V31-I36 HydrophobicContact CG1-CD1 3.94Å; V31-I36 HydrophobicContact CG1-CG1 4.23Å
32	K	64.3	Low	61.3	Low	162 Å²	162	116.3 Å²	116.3	70%	0.704	68%	0.678	S	S	*	*			trans	-61.2	112.1	173.2	-126.8	175.8	-176.6	177.2	0	106.7	P30 S34 S35	P30-K32 PolarHBondContact O-N 3.43Å; K32-S34 PolarHBondContact O-N 3.21Å; K32-S35 VanDerWaalsContact O-CB 3.26Å; K32-S35 WeakPolarHBondContact O-CB 3.02Å; K32-S35 PolarHBondContact O-N 2.85Å
33	L	59.5	Low	60.8	Low	134 Å²	134	120 Å²	120	70%	0.702	70%	0.698	S	S	*	*	G	3₁₀ helix	trans	-56.2	-21.3	-179.8	-66.6	174.9	0	0	0	112.8	V31 S35 I36	V31-L33 PolarHBondContact O-N 3.18Å; L33-S35 PolarHBondContact O-N 3Å; L33-I36 HydrophobicContact CD2-CD1 3.9Å; L33-I36 PolarHBondContact O-N 3.07Å
34	S	58.8	Low	60.6	Low	96 Å²	96	119.9 Å²	119.9	67%	0.671	70%	0.704	S	S	*	*	G	3₁₀ helix	trans	-63.8	-13.8	171.5	63.9	0	0	0	0	114.3	K32	K32-S34 PolarHBondContact O-N 3.21Å
35	S	57.9	Low	60.6	Low	94 Å²	94	123.4 Å²	123.4	66%	0.657	72%	0.715	S	S	*	*	G	3₁₀ helix	trans	-90.4	-13.1	176.5	178.6	0	0	0	0	113.2	K32 L33	K32-S35 VanDerWaalsContact O-CB 3.26Å; K32-S35 WeakPolarHBondContact O-CB 3.02Å; K32-S35 PolarHBondContact O-N 2.85Å; L33-S35 PolarHBondContact O-N 3Å
36	I	59.7	Low	60.7	Low	110 Å²	110	125.8 Å²	125.8	56%	0.564	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.3	-16.2	-173.1	-56.3	-179.4	0	0	0	111.1	V31 L33	V31-I36 HydrophobicContact CG1-CD1 3.94Å; V31-I36 HydrophobicContact CG1-CG1 4.23Å; L33-I36 HydrophobicContact CD2-CD1 3.9Å; L33-I36 PolarHBondContact O-N 3.07Å
37	I	59.9	Low	60.2	Low	125 Å²	125	125.9 Å²	125.9	64%	0.641	74%	0.736	S	S	*	*			trans	-107.7	70.6	-177.9	-45.3	175.5	0	0	0	108.8	V39	I37-V39 HydrophobicContact CG2-CG2 3.51Å; I37-V39 PolarHBondContact O-N 2.97Å
38	E	62	Low	59.4	Low	184 Å²	184	134.1 Å²	134.1	86%	0.86	77%	0.766	S	S	*	*			trans	-79.6	99.3	145.6	-86.5	-174.4	159.8	0	0	106.2	P40	E38-P40 WeakPolarHBondContact O-CD 3.2Å
39	V	65.2	Low	59.1	Low	111 Å²	111	135.1 Å²	135.1	67%	0.673	76%	0.763	S	S	*	*			trans	-68.1	116.4	166.9	-175.8	0	0	0	0	106.5	I37 S41	I37-V39 HydrophobicContact CG2-CG2 3.51Å; I37-V39 PolarHBondContact O-N 2.97Å; V39-S41 PolarHBondContact O-N 2.79Å
40	P	53.8	Low	58.9	Low	106 Å²	106	135.1 Å²	135.1	69%	0.688	77%	0.767	S	S	*	*			trans	-67.7	105.4	167.2	27.3	-29.6	0	0	0	107.2	E38 A42	E38-P40 WeakPolarHBondContact O-CD 3.2Å; P40-A42 HydrophobicContact CB-CB 4.41Å; P40-A42 PolarHBondContact O-N 2.67Å
41	S	59	Low	58.7	Low	116 Å²	116	135.7 Å²	135.7	81%	0.811	77%	0.765	S	S	*	*			trans	-69.2	59	166.3	-179.5	0	0	0	0	109.9	V39	V39-S41 PolarHBondContact O-N 2.79Å
42	A	59.5	Low	58.4	Low	87 Å²	87	138.1 Å²	138.1	72%	0.719	78%	0.775	S	S	*	*			trans	-121.9	21.1	-177.7	0	0	0	0	0	112.2	P40	P40-A42 HydrophobicContact CB-CB 4.41Å; P40-A42 PolarHBondContact O-N 2.67Å
43	L	54.5	Low	58.1	Low	170 Å²	170	136.6 Å²	136.6	89%	0.89	78%	0.78	S	S	*	*			trans	-121.9	20.3	179.3	-127.3	143.6	0	0	0	112.8
44	A	56.3	Low	58	Low	90 Å²	90	136.7 Å²	136.7	74%	0.744	79%	0.785	S	S	*	*	S	Bend	trans	-106.7	28.5	176.4	0	0	0	0	0	112.9
45	L	61	Low	57.9	Low	162 Å²	162	139.6 Å²	139.6	85%	0.848	79%	0.793	S	S	*	*	S	Bend	trans	-133.8	20.4	-177.8	-98.5	172.3	0	0	0	114.2
46	L	62.3	Low	57.9	Low	167 Å²	167	143.2 Å²	143.2	87%	0.874	80%	0.803	S	S	*	*	S	Bend	trans	-148	66.2	173.6	-69.3	174.5	0	0	0	110.4
47	D	52.2	Low	57.8	Low	162 Å²	162	145.9 Å²	145.9	87%	0.866	82%	0.823	S	S	*	*			trans	-167.8	113.3	140.8	-133.8	-128.4	0	0	0	108.1
48	E	47.7	Very low	57.6	Low	271 Å²	271	147.8 Å²	147.8	100%	1.266	84%	0.84	S	S	*	*			trans	56.1	0	179.6	-76.7	-159.8	98.9	0	0	120.8

Retrieved 48 of 48 residues in 22 ms (Link to these results)

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