A0A087WWR8_HUMAN Loading...

Sulfatase 1

AlphaFold DB , UniProt , Accession A0A087WWR8, Species HUMAN (Homo sapiens, Human), Gene SULF1, Length 669 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M90.1Very high90.5Very high182 Ų18286.5 Ų86.590%0.89752%0.52SS*.  0156.30175.8166.654.800108.7I3 L80M1-I3 HydrophobicContact CE-CD1 3.89Å; M1-I3 HydrophobicContact CE-CG1 4.33Å; M1-I3 HydrophobicContact CG-CG1 4.09Å; M1-I3 HydrophobicContact SD-CD1 4.17Å; M1-I3 HydrophobicContact SD-CG1 4.15Å; M1-L80 HydrophobicContact CE-CD1 3.53Å
2V93.7Very high90.6Very high137 Ų13779.4 Ų79.483%0.8348%0.477SS*.  trans-127.4119.8169.5-179.70000108.1
3I94.3Very high90.6Very high85 Ų8575.9 Ų75.944%0.43645%0.454SS..  trans-110.5132.4171.1-55.3179.4000106.4M1 H5 L80M1-I3 HydrophobicContact CE-CD1 3.89Å; M1-I3 HydrophobicContact CE-CG1 4.33Å; M1-I3 HydrophobicContact CG-CG1 4.09Å; M1-I3 HydrophobicContact SD-CD1 4.17Å; M1-I3 HydrophobicContact SD-CG1 4.15Å; I3-H5 WeakPolarHBondContact CG2-CE1 3.22Å; I3-L80 HydrophobicContact CD1-CD1 4.46Å; I3-L80 HydrophobicContact CD1-CD2 4.09Å
4S94.2Very high90.6Very high111 Ų11170.9 Ų70.978%0.77642%0.424SS*.  trans-133.784-174.7177.20000108.7
5H92.9Very high90.6Very high72 Ų7267.9 Ų67.933%0.33341%0.411SS..  trans-60.4139.8175.6-58.278.1000110.7I3 V73 S76I3-H5 WeakPolarHBondContact CG2-CE1 3.22Å; H5-V73 HydrophobicContact CB-CG1 4.33Å; H5-V73 HydrophobicContact CB-CG2 3.93Å; H5-S76 VanDerWaalsContact NE2-CB 3.29Å; H5-S76 WeakPolarHBondContact NE2-CB 3.42Å; H5-S76 PolarHBondContact NE2-OG 3.08Å
6A91Very high90.6Very high85 Ų8570.3 Ų70.370%0.70243%0.428SS*.  trans-79.9-25.3170.700000111.8H9A6-H9 WeakPolarHBondContact O-CA 3.48Å; A6-H9 WeakPolarHBondContact O-CB 3.36Å; A6-H9 PolarHBondContact O-N 3.3Å
7A91.9Very high90.7Very high30 Ų3073.2 Ų73.225%0.24844%0.436CS..THydrogen-bonded Turntrans-64.3141.717500000111.3T69 V73A7-T69 HydrophobicContact CB-CG2 3.73Å; A7-V73 HydrophobicContact CB-CG2 3.62Å
8P91.8Very high90.8Very high30 Ų3070.1 Ų70.120%0.19542%0.416CS..THydrogen-bonded Turncis-97.5402.838.5-34.8000113.2R66 L70P8-R66 HydrophobicContact CB-CB 4.15Å; P8-R66 HydrophobicContact CB-CG 4.32Å; P8-R66 WeakPolarHBondContact CB-O 3.45Å; P8-R66 PolarHBondContact O-NH1 3.1Å; P8-L70 HydrophobicContact CG-CD1 4.47Å
9H87.9Confident90.7Very high113 Ų11368.1 Ų68.152%0.52341%0.405SS..SBendtrans-68.3148.6172.2-168.7-79000111.6A6A6-H9 WeakPolarHBondContact O-CA 3.48Å; A6-H9 WeakPolarHBondContact O-CB 3.36Å; A6-H9 PolarHBondContact O-N 3.3Å
10G82.4Confident90.7Very high22 Ų2273.8 Ų73.823%0.22743%0.425CS..SBendtrans-65149.9179.300000114.8E12G10-E12 WeakPolarHBondContact CA-OE1 3.45Å; G10-E12 PolarHBondContact N-OE1 3.19Å
11P85.3Confident90.8Very high85 Ų8573.5 Ų73.555%0.55242%0.421SS*.SBendcis-68.7131.9-0.129.7-35000111.7D13P11-D13 PolarHBondContact O-N 3.34Å
12E91.3Very high90.9Very high1 Ų169.3 Ų69.31%0.00540%0.396CS..  trans-83.354.2-169.8-5684.3-179.300111.2G10 L62 K65 R66 T69 K112 H537 W538G10-E12 WeakPolarHBondContact CA-OE1 3.45Å; G10-E12 PolarHBondContact N-OE1 3.19Å; E12-L62 HydrophobicContact CB-CD1 4.37Å; E12-L62 HydrophobicContact CG-CD1 3.7Å; E12-L62 WeakPolarHBondContact OE1-CD1 3.49Å; E12-K65 HydrophobicContact CB-CB 3.94Å; E12-K65 WeakPolarHBondContact O-CB 3.25Å; E12-K65 WeakPolarHBondContact O-CD 3.31Å; E12-R66 HydrophobicContact CB-CG 4.36Å; E12-R66 HydrophobicContact CG-CG 3.87Å; E12-T69 PolarHBondContact O-OG1 2.92Å; E12-K112 VanDerWaalsContact CD-NZ 3.34Å; E12-K112 IonicContact OE1-NZ 3.98Å; E12-K112 PolarHBondContact OE1-NZ 2.63Å; E12-K112 IonicContact OE2-NZ 3.02Å; E12-K112 PolarHBondContact OE2-NZ 3Å; E12-H537 IonicContact OE1-NE2 3.03Å; E12-H537 IonicContact OE2-CE1 3.11Å; E12-H537 IonicContact OE2-NE2 2.64Å; E12-H537 PolarHBondContact OE2-NE2 2.98Å; E12-W538 PolarHBondContact OE2-NE1 3.15Å; E12-W538 VanDerWaalsContact OE2-NE1 3.09Å
13D90.9Very high90.6Very high34 Ų3466.5 Ų66.518%0.18238%0.381CS..PPolyproline II helixtrans-90.4122.2-179.3-80.2-57.5000111.1P11 K65 T69 Q539 T540P11-D13 PolarHBondContact O-N 3.34Å; D13-K65 IonicContact OD1-NZ 3.98Å; D13-T69 WeakPolarHBondContact O-CG2 3.4Å; D13-T69 PolarHBondContact O-OG1 3.38Å; D13-Q539 VanDerWaalsContact CG-N 3.26Å; D13-Q539 PolarHBondContact OD1-N 2.96Å; D13-Q539 PolarHBondContact OD2-N 3.08Å; D13-T540 HydrophobicContact CB-CG2 4.02Å; D13-T540 WeakPolarHBondContact OD1-CB 3.4Å; D13-T540 PolarHBondContact OD1-N 3.21Å; D13-T540 PolarHBondContact OD1-OG1 2.9Å
14S90.8Very high90.3Very high5 Ų569.2 Ų69.24%0.03540%0.397CS..PPolyproline II helixtrans-84.4150.8-178.560.40000112Q68S14-Q68 VanDerWaalsContact CB-CB 3.5Å
15A90.9Very high90.2Very high27 Ų2764.3 Ų64.322%0.22336%0.363CS..PPolyproline II helixtrans-59.3145.7168.400000110.7Q17 F18A15-Q17 VanDerWaalsContact C-N 3.26Å; A15-Q17 VanDerWaalsContact CB-OE1 3.31Å; A15-Q17 PolarHBondContact O-N 3.39Å; A15-Q17 VanDerWaalsContact O-N 3.08Å; A15-F18 HydrophobicContact CB-CD2 3.94Å; A15-F18 HydrophobicContact CB-CE2 4.24Å; A15-F18 PolarHBondContact O-N 3.07Å
16P90.2Very high90.1Very high105 Ų10564.2 Ų64.268%0.68237%0.37SS*.G310 helixtrans-54.7-35.9-166.8-29.636.5000115F18 S19P16-F18 VanDerWaalsContact C-N 3.26Å; P16-F18 PolarHBondContact O-N 3.37Å; P16-S19 WeakPolarHBondContact O-CB 3.42Å; P16-S19 PolarHBondContact O-N 3.28Å; P16-S19 PolarHBondContact O-OG 2.91Å
17Q91.5Very high90Very high121 Ų12166.3 Ų66.357%0.56537%0.365SS*.G310 helixtrans-63.3-27.6178.469.5-8220.100113.7A15A15-Q17 VanDerWaalsContact C-N 3.26Å; A15-Q17 VanDerWaalsContact CB-OE1 3.31Å; A15-Q17 PolarHBondContact O-N 3.39Å; A15-Q17 VanDerWaalsContact O-N 3.08Å
18F93.2Very high90Very high17 Ų1765.4 Ų65.48%0.07536%0.356CS..G310 helixtrans-93.9-9.9-178.7-53-49.1000113.7A15 P16 K20 L21 Q68 M71 S72 D75A15-F18 HydrophobicContact CB-CD2 3.94Å; A15-F18 HydrophobicContact CB-CE2 4.24Å; A15-F18 PolarHBondContact O-N 3.07Å; P16-F18 VanDerWaalsContact C-N 3.26Å; P16-F18 PolarHBondContact O-N 3.37Å; F18-K20 PolarHBondContact O-N 3.08Å; F18-L21 HydrophobicContact CB-CD1 4.12Å; F18-L21 HydrophobicContact CD1-CD1 3.76Å; F18-L21 HydrophobicContact CG-CD1 4.37Å; F18-L21 WeakPolarHBondContact O-CB 3.38Å; F18-L21 PolarHBondContact O-N 3.15Å; F18-Q68 HydrophobicContact CB-CB 4.47Å; F18-Q68 WeakPolarHBondContact CB-O 3.25Å; F18-Q68 WeakPolarHBondContact O-CG 3.4Å; F18-M71 HydrophobicContact CB-CB 4.23Å; F18-M71 HydrophobicContact CD1-CB 3.61Å; F18-M71 HydrophobicContact CD1-CG 4.11Å; F18-M71 HydrophobicContact CD2-CB 3.6Å; F18-M71 HydrophobicContact CE1-CB 3.76Å; F18-M71 HydrophobicContact CE2-CB 3.75Å; F18-M71 HydrophobicContact CG-CB 3.53Å; F18-M71 HydrophobicContact CG-CG 4.21Å; F18-M71 HydrophobicContact CZ-CB 3.83Å; F18-S72 WeakPolarHBondContact CE2-OG 3.49Å; F18-D75 WeakPolarHBondContact CZ-OD1 3.43Å
19S89.1Confident90.1Very high31 Ų3168 Ų6822%0.21737%0.367CS..THydrogen-bonded Turntrans-57-17.9-175.163.50000115.8P16 Q68P16-S19 WeakPolarHBondContact O-CB 3.42Å; P16-S19 PolarHBondContact O-N 3.28Å; P16-S19 PolarHBondContact O-OG 2.91Å; S19-Q68 VanDerWaalsContact C-NE2 3.34Å; S19-Q68 PolarHBondContact O-NE2 2.78Å
20K90.3Very high90.5Very high182 Ų18264.4 Ų64.479%0.79135%0.353SS*.THydrogen-bonded Turntrans-100-6.2178.7-60.3-175.9-178.5177.80114.3F18F18-K20 PolarHBondContact O-N 3.08Å
21L92.2Very high91.2Very high68 Ų6866.8 Ų66.836%0.35637%0.365SS..SBendtrans-76.1161.9-177.7-62.3178.7000112.2F18 Q68 M71F18-L21 HydrophobicContact CB-CD1 4.12Å; F18-L21 HydrophobicContact CD1-CD1 3.76Å; F18-L21 HydrophobicContact CG-CD1 4.37Å; F18-L21 WeakPolarHBondContact O-CB 3.38Å; F18-L21 PolarHBondContact O-N 3.15Å; L21-Q68 HydrophobicContact CB-CG 4.39Å; L21-Q68 PolarHBondContact O-NE2 3.44Å; L21-M71 HydrophobicContact CD1-CG 3.88Å
22Y92.9Very high91.7Very high94 Ų9462.9 Ų62.937%0.36934%0.339SS..  trans52.144.8175.1-49.5-72.8000116.4N24 A25 R64 L67 Q68 M71Y22-N24 PolarHBondContact O-N 2.91Å; Y22-N24 VanDerWaalsContact O-N 3.12Å; Y22-A25 WeakPolarHBondContact O-CB 3.23Å; Y22-A25 PolarHBondContact O-N 3.44Å; Y22-R64 WeakPolarHBondContact O-CG 3.3Å; Y22-L67 HydrophobicContact CD1-CB 4.45Å; Y22-L67 HydrophobicContact CD1-CD1 4.04Å; Y22-L67 HydrophobicContact CD2-CB 3.48Å; Y22-L67 VanDerWaalsContact CD2-CB 3.48Å; Y22-L67 HydrophobicContact CD2-CD1 4.45Å; Y22-L67 HydrophobicContact CE2-CB 3.77Å; Y22-L67 HydrophobicContact CG-CB 3.86Å; Y22-L67 HydrophobicContact CG-CD1 3.97Å; Y22-Q68 HydrophobicContact CD2-CG 4.25Å; Y22-M71 HydrophobicContact CE2-CG 3.98Å; Y22-M71 HydrophobicContact CE2-SD 4.13Å; Y22-M71 PolarHBondContact OH-SD 2.93Å
23P88.4Confident91.9Very high78 Ų7864 Ų6451%0.50634%0.344SS..THydrogen-bonded Turntrans-53.8-37.8-178.521.9-33.1000112.9R64P23-R64 VanDerWaalsContact O-CZ 3.27Å; P23-R64 PolarHBondContact O-NE 3.07Å; P23-R64 PolarHBondContact O-NH2 3.43Å
24N88Confident92.2Very high143 Ų14364.3 Ų64.377%0.76535%0.345SS*.THydrogen-bonded Turntrans-107.648.2-175.6-59.9-11000112.8Y22 S26Y22-N24 PolarHBondContact O-N 2.91Å; Y22-N24 VanDerWaalsContact O-N 3.12Å; N24-S26 VanDerWaalsContact C-N 3.35Å; N24-S26 PolarHBondContact O-N 3.29Å
25A91Very high92.4Very high8 Ų869 Ų697%0.06636%0.363CS..  trans-73.670.1-175.300000115.2Y22 H28 Q63 R64 L67Y22-A25 WeakPolarHBondContact O-CB 3.23Å; Y22-A25 PolarHBondContact O-N 3.44Å; A25-H28 PolarHBondContact O-ND1 3.29Å; A25-Q63 HydrophobicContact CB-CG 4.13Å; A25-Q63 WeakPolarHBondContact O-CG 3.46Å; A25-R64 HydrophobicContact CB-CB 4.11Å; A25-L67 HydrophobicContact CB-CD1 3.92Å
26S91Very high92.5Very high69 Ų6968.7 Ų68.748%0.48336%0.36SS..  trans-88.30.2-176.757.40000115.8N24 H28 I29N24-S26 VanDerWaalsContact C-N 3.35Å; N24-S26 PolarHBondContact O-N 3.29Å; S26-H28 PolarHBondContact O-N 3.46Å; S26-I29 WeakPolarHBondContact O-CB 3.31Å; S26-I29 PolarHBondContact O-N 2.85Å
27Q88.9Confident92.6Very high129 Ų12967.3 Ų67.360%0.60335%0.352SS*.THydrogen-bonded Turntrans-61.7-15.3-171.7-59.182.9-0.800114.8I29Q27-I29 VanDerWaalsContact C-N 3.33Å
28H91.8Very high92.6Very high11 Ų1161.7 Ų61.75%0.05133%0.325CS..THydrogen-bonded Turntrans-81-10.7175.976.3-77.8000113.5A25 S26 T30 Y33 N60 Q63 I105 Q107A25-H28 PolarHBondContact O-ND1 3.29Å; S26-H28 PolarHBondContact O-N 3.46Å; H28-T30 PolarHBondContact O-N 3.13Å; H28-Y33 AromaticContact CD2-CD2 3.85Å; H28-Y33 AromaticContact CD2-CE2 3.49Å; H28-Y33 VanDerWaalsContact CD2-CE2 3.49Å; H28-Y33 WeakPolarHBondContact CD2-CE2 3.41Å; H28-Y33 AromaticContact NE2-CE2 3.4Å; H28-Y33 WeakPolarHBondContact NE2-CE2 3.29Å; H28-Y33 AromaticContact NE2-CZ 3.92Å; H28-N60 PolarHBondContact CE1-OD1 3.31Å; H28-Q63 HydrophobicContact CB-CB 4.25Å; H28-Q63 HydrophobicContact CB-CG 3.97Å; H28-Q63 WeakPolarHBondContact ND1-CB 3.44Å; H28-I105 HydrophobicContact CB-CB 4.26Å; H28-I105 HydrophobicContact CB-CG2 4.35Å; H28-Q107 PolarHBondContact O-NE2 2.85Å
29I95.1Very high92.5Very high85 Ų8567.1 Ų67.144%0.43635%0.353SS..  trans-85.789.2-179-55.5178.2000108.9S26 Q27 Y33S26-I29 WeakPolarHBondContact O-CB 3.31Å; S26-I29 PolarHBondContact O-N 2.85Å; Q27-I29 VanDerWaalsContact C-N 3.33Å; I29-Y33 HydrophobicContact CB-CG 4.46Å; I29-Y33 HydrophobicContact CG1-CD1 4.43Å; I29-Y33 HydrophobicContact CG1-CD2 4.46Å; I29-Y33 HydrophobicContact CG1-CE1 4.33Å; I29-Y33 HydrophobicContact CG1-CE2 4.39Å; I29-Y33 HydrophobicContact CG1-CG 4.48Å; I29-Y33 HydrophobicContact CG2-CD1 3.9Å; I29-Y33 HydrophobicContact CG2-CE1 4.39Å; I29-Y33 HydrophobicContact CG2-CG 4.18Å
30T95.3Very high92.6Very high37 Ų3768.1 Ų68.123%0.22736%0.355CS..  trans-95.6168.7174.853.10000111.4H28 S32 Y33 Q107 Y592H28-T30 PolarHBondContact O-N 3.13Å; T30-S32 PolarHBondContact O-N 3.04Å; T30-S32 VanDerWaalsContact O-N 3.09Å; T30-S32 PolarHBondContact OG1-OG 3.2Å; T30-Y33 WeakPolarHBondContact O-CB 3.44Å; T30-Y33 PolarHBondContact O-N 3.08Å; T30-Y33 PolarHBondContact OG1-N 2.95Å; T30-Q107 PolarHBondContact OG1-NE2 3.21Å; T30-Y592 HydrophobicContact CG2-CD1 4.19Å; T30-Y592 HydrophobicContact CG2-CE1 3.8Å
31P96.7Very high92.8Very high73 Ų7359.4 Ų59.447%0.47432%0.318SS..THydrogen-bonded Turntrans-56.1-22169.2-29.938.9000115Y592 L594P31-Y592 HydrophobicContact CB-CD2 3.94Å; P31-Y592 HydrophobicContact CB-CE2 4.41Å; P31-Y592 HydrophobicContact CB-CG 4.19Å; P31-Y592 HydrophobicContact CG-CD2 3.63Å; P31-Y592 HydrophobicContact CG-CE2 3.59Å; P31-Y592 HydrophobicContact CG-CG 4.17Å; P31-L594 HydrophobicContact CB-CD1 4.18Å
32S95.7Very high92.7Very high2 Ų256.2 Ų56.21%0.01430%0.301CS..THydrogen-bonded Turntrans-84.6-9.6172.248.90000114.4T30 N34 Y35 Q107 F108 Y592T30-S32 PolarHBondContact O-N 3.04Å; T30-S32 VanDerWaalsContact O-N 3.09Å; T30-S32 PolarHBondContact OG1-OG 3.2Å; S32-N34 PolarHBondContact O-N 3Å; S32-Y35 WeakPolarHBondContact O-CB 3.21Å; S32-Y35 PolarHBondContact O-N 3.28Å; S32-Q107 CarbonylContact O-C 3.57Å; S32-Q107 WeakPolarHBondContact O-CA 3.47Å; S32-F108 PolarHBondContact O-N 3.04Å; S32-Y592 WeakPolarHBondContact CB-O 3.47Å
33Y96.9Very high92.5Very high25 Ų2554.5 Ų54.510%0.09829%0.294CS..BIsolated β-bridgetrans-65.8126.6176.3178.1-93.4000110.5H28 I29 T30 Y35 M51 M56 T59 I105H28-Y33 AromaticContact CD2-CD2 3.85Å; H28-Y33 AromaticContact CD2-CE2 3.49Å; H28-Y33 VanDerWaalsContact CD2-CE2 3.49Å; H28-Y33 WeakPolarHBondContact CD2-CE2 3.41Å; H28-Y33 AromaticContact NE2-CE2 3.4Å; H28-Y33 WeakPolarHBondContact NE2-CE2 3.29Å; H28-Y33 AromaticContact NE2-CZ 3.92Å; I29-Y33 HydrophobicContact CB-CG 4.46Å; I29-Y33 HydrophobicContact CG1-CD1 4.43Å; I29-Y33 HydrophobicContact CG1-CD2 4.46Å; I29-Y33 HydrophobicContact CG1-CE1 4.33Å; I29-Y33 HydrophobicContact CG1-CE2 4.39Å; I29-Y33 HydrophobicContact CG1-CG 4.48Å; I29-Y33 HydrophobicContact CG2-CD1 3.9Å; I29-Y33 HydrophobicContact CG2-CE1 4.39Å; I29-Y33 HydrophobicContact CG2-CG 4.18Å; T30-Y33 WeakPolarHBondContact O-CB 3.44Å; T30-Y33 PolarHBondContact O-N 3.08Å; T30-Y33 PolarHBondContact OG1-N 2.95Å; Y33-Y35 PolarHBondContact O-N 3.19Å; Y33-Y35 VanDerWaalsContact O-N 3.11Å; Y33-M51 HydrophobicContact CD2-CE 4.16Å; Y33-M51 HydrophobicContact CE1-CE 4.03Å; Y33-M51 HydrophobicContact CE2-CE 3.6Å; Y33-M56 HydrophobicContact CE1-CE 4.32Å; Y33-M56 PolarHBondContact OH-O 3.12Å; Y33-T59 PolarHBondContact OH-OG1 3.11Å; Y33-I105 WeakPolarHBondContact CD2-O 3.49Å
34N95.9Very high92.6Very high40 Ų4050.8 Ų50.821%0.21427%0.27CS..THydrogen-bonded Turntrans56.516.7-174.5-155.414.7000115.8S32 A36 M51 G106S32-N34 PolarHBondContact O-N 3Å; N34-A36 PolarHBondContact O-N 3.01Å; N34-M51 HydrophobicContact CB-CE 3.93Å; N34-M51 VanDerWaalsContact OD1-CB 3.32Å; N34-M51 WeakPolarHBondContact OD1-CB 3.05Å; N34-M51 PolarHBondContact OD1-N 2.89Å; N34-G106 PolarHBondContact N-O 2.77Å
35Y95.4Very high92.8Very high103 Ų10344 Ų4440%0.40423%0.233SC..  trans-76.886.4177.2-169.9-94.9000110.2S32 Y33 N38 F108 L594S32-Y35 WeakPolarHBondContact O-CB 3.21Å; S32-Y35 PolarHBondContact O-N 3.28Å; Y33-Y35 PolarHBondContact O-N 3.19Å; Y33-Y35 VanDerWaalsContact O-N 3.11Å; Y35-N38 WeakPolarHBondContact CD1-OD1 3.42Å; Y35-N38 WeakPolarHBondContact CE1-OD1 3.27Å; Y35-N38 PolarHBondContact O-ND2 3.36Å; Y35-N38 PolarHBondContact O-OD1 3.07Å; Y35-F108 HydrophobicContact CD1-CD1 4.12Å; Y35-F108 HydrophobicContact CD1-CE1 4.17Å; Y35-F108 WeakPolarHBondContact O-CA 3.32Å; Y35-L594 HydrophobicContact CD1-CD2 4.26Å; Y35-L594 HydrophobicContact CD2-CD2 4.47Å; Y35-L594 HydrophobicContact CE1-CB 4.44Å; Y35-L594 WeakPolarHBondContact CE1-O 3.32Å; Y35-L594 HydrophobicContact CG-CD2 4.18Å
36A93.1Very high92.7Very high21 Ų2146.5 Ų46.517%0.17424%0.244CC..  trans-155.6151.9-17400000112.8N34N34-A36 PolarHBondContact O-N 3.01Å
37P92.3Very high92.5Very high77 Ų7751.8 Ų51.850%0.525%0.254SS..  cis-81.2159.81.935.1-36.2000113.3T48P37-T48 WeakPolarHBondContact CA-O 3.45Å
38N92.6Very high92.5Very high2 Ų246.5 Ų46.51%0.01123%0.231CC..  trans-117.396-177.7-57.5-96.7000110.5Y35 D40 K41 M45 Q46Y35-N38 WeakPolarHBondContact CD1-OD1 3.42Å; Y35-N38 WeakPolarHBondContact CE1-OD1 3.27Å; Y35-N38 PolarHBondContact O-ND2 3.36Å; Y35-N38 PolarHBondContact O-OD1 3.07Å; N38-D40 VanDerWaalsContact C-N 3.28Å; N38-D40 PolarHBondContact O-N 2.78Å; N38-K41 HydrophobicContact CB-CB 4.03Å; N38-K41 HydrophobicContact CB-CD 3.91Å; N38-K41 HydrophobicContact CB-CG 3.96Å; N38-K41 WeakPolarHBondContact OD1-CE 3.39Å; N38-M45 HydrophobicContact CB-CB 3.84Å; N38-M45 PolarHBondContact N-O 3.3Å; N38-M45 CarbonylContact O-C 3.52Å; N38-Q46 WeakPolarHBondContact O-CG 3.42Å; N38-Q46 PolarHBondContact O-N 3.33Å
39M90.4Very high92.5Very high132 Ų13247.6 Ų47.665%0.6525%0.245SC*.THydrogen-bonded Turntrans-76-17.4179.3-62.6-54.1-57.600113.3Q46M39-Q46 HydrophobicContact CE-CB 4.46Å; M39-Q46 HydrophobicContact SD-CB 4.23Å
40D91.8Very high92.4Very high51 Ų5147.4 Ų47.427%0.27325%0.25SC..THydrogen-bonded Turntrans-82.8-11.3177.769.9-56.5000113.4N38 F581 N596N38-D40 VanDerWaalsContact C-N 3.28Å; N38-D40 PolarHBondContact O-N 2.78Å; D40-F581 WeakPolarHBondContact O-CE1 3.48Å; D40-F581 VanDerWaalsContact O-CZ 3.29Å; D40-F581 WeakPolarHBondContact O-CZ 3.39Å; D40-N596 HydrophobicContact CB-CB 4.05Å; D40-N596 VanDerWaalsContact O-CB 3.26Å; D40-N596 WeakPolarHBondContact O-CB 3.47Å; D40-N596 PolarHBondContact O-ND2 2.87Å; D40-N596 WeakPolarHBondContact OD2-CB 3.47Å; D40-N596 PolarHBondContact OD2-N 3.01Å
41K93.2Very high92.4Very high0 Ų046.2 Ų46.20%024%0.242CC..SBendtrans-109.5174.3-176.5-59.6-174.6-144.5-52.40111.5N38 M45 Q46 F108 F581 E583 F585 Q593 L594N38-K41 HydrophobicContact CB-CB 4.03Å; N38-K41 HydrophobicContact CB-CD 3.91Å; N38-K41 HydrophobicContact CB-CG 3.96Å; N38-K41 WeakPolarHBondContact OD1-CE 3.39Å; K41-M45 HydrophobicContact CB-CB 3.8Å; K41-M45 HydrophobicContact CB-CG 3.8Å; K41-M45 HydrophobicContact CD-CG 4.35Å; K41-Q46 VanDerWaalsContact O-CG 3.27Å; K41-Q46 WeakPolarHBondContact O-CG 3.49Å; K41-Q46 PolarHBondContact O-NE2 3.44Å; K41-F108 HydrophobicContact CD-CE1 4.48Å; K41-F108 HydrophobicContact CD-CZ 4.5Å; K41-F581 WeakPolarHBondContact O-CZ 3.12Å; K41-E583 WeakPolarHBondContact CA-OE1 3.45Å; K41-E583 WeakPolarHBondContact CB-OE1 3.37Å; K41-F585 HydrophobicContact CD-CZ 4.38Å; K41-F585 HydrophobicContact CG-CZ 4.39Å; K41-Q593 WeakPolarHBondContact CE-O 3.41Å; K41-Q593 PolarHBondContact NZ-O 3.1Å; K41-L594 PolarHBondContact NZ-O 3.13Å
42H91.1Very high92.2Very high0 Ų047.5 Ų47.50%024%0.244CC..  trans-61.3158.6-178.571-82.4000113.4I44 M45 Q46 Y118 N558 F577 F581 E583H42-I44 VanDerWaalsContact C-N 3.26Å; H42-I44 PolarHBondContact O-N 3.46Å; H42-M45 PolarHBondContact O-N 2.87Å; H42-Q46 PolarHBondContact O-N 3.27Å; H42-Y118 AromaticContact CE1-CZ 3.91Å; H42-Y118 PolarHBondContact CE1-OH 2.7Å; H42-Y118 VanDerWaalsContact CE1-OH 3.23Å; H42-Y118 PolarHBondContact ND1-OH 3.32Å; H42-Y118 VanDerWaalsContact ND1-OH 3.11Å; H42-N558 PolarHBondContact NE2-ND2 2.68Å; H42-F577 HydrophobicContact CB-CD1 3.69Å; H42-F577 HydrophobicContact CB-CD2 4.01Å; H42-F577 HydrophobicContact CB-CE1 3.39Å; H42-F577 HydrophobicContact CB-CE2 3.75Å; H42-F577 HydrophobicContact CB-CG 4Å; H42-F577 HydrophobicContact CB-CZ 3.43Å; H42-F577 VanDerWaalsContact CB-CZ 3.43Å; H42-F577 AromaticContact CD2-CE1 3.48Å; H42-F577 VanDerWaalsContact CD2-CE1 3.48Å; H42-F577 WeakPolarHBondContact CD2-CE1 3.18Å; H42-F577 AromaticContact CD2-CZ 4Å; H42-F577 AromaticContact CG-CE1 3.25Å; H42-F577 AromaticContact CG-CZ 3.34Å; H42-F577 AromaticContact ND1-CE1 3.69Å; H42-F577 AromaticContact ND1-CZ 3.37Å; H42-F577 WeakPolarHBondContact ND1-CZ 3.36Å; H42-F581 HydrophobicContact CB-CD1 4.26Å; H42-E583 IonicContact CG-OE1 2.91Å; H42-E583 PolarHBondContact N-OE1 3.16Å; H42-E583 IonicContact ND1-OE1 3.3Å; H42-E583 PolarHBondContact ND1-OE1 2.91Å; H42-E583 IonicContact ND1-OE2 3.04Å
43W88.3Confident92.1Very high58 Ų5852.4 Ų52.422%0.2228%0.276CS..Hα-helixtrans-46.4-36.1-166.173-79.6000116.5M45 Q46 Y47 L528 N558W43-M45 VanDerWaalsContact C-N 3.33Å; W43-M45 PolarHBondContact O-N 3.48Å; W43-Q46 WeakPolarHBondContact O-CB 3.41Å; W43-Q46 PolarHBondContact O-N 3.04Å; W43-Y47 HydrophobicContact CE3-CD2 4.04Å; W43-Y47 HydrophobicContact CE3-CE2 4.42Å; W43-Y47 VanDerWaalsContact O-CD2 3.31Å; W43-Y47 WeakPolarHBondContact O-CD2 3.28Å; W43-Y47 PolarHBondContact O-N 3.05Å; W43-Y47 VanDerWaalsContact O-N 3.15Å; W43-L528 HydrophobicContact CH2-CD2 3.68Å; W43-L528 HydrophobicContact CH2-CG 4.29Å; W43-L528 HydrophobicContact CZ3-CD2 3.79Å; W43-L528 HydrophobicContact CZ3-CG 4.17Å; W43-N558 PolarHBondContact NE1-OD1 3.32Å; W43-N558 VanDerWaalsContact NE1-OD1 3.16Å
44I89.9Confident91.9Very high0 Ų053.1 Ų53.10%028%0.281CS..Hα-helixtrans-62.5-43.3178.5-56-174.3000110.1H42 Q46 Y47 T48 M116 L528 N558H42-I44 VanDerWaalsContact C-N 3.26Å; H42-I44 PolarHBondContact O-N 3.46Å; I44-Q46 PolarHBondContact O-N 3.16Å; I44-Y47 CarbonylContact O-C 3.42Å; I44-Y47 PolarHBondContact O-N 3.34Å; I44-Y47 VanDerWaalsContact O-N 3.17Å; I44-T48 WeakPolarHBondContact O-CB 3.26Å; I44-T48 PolarHBondContact O-N 3.14Å; I44-T48 PolarHBondContact O-OG1 2.99Å; I44-M116 HydrophobicContact CD1-CE 4.28Å; I44-M116 HydrophobicContact CG2-CE 4.14Å; I44-L528 HydrophobicContact CD1-CD2 4.2Å; I44-L528 HydrophobicContact CG1-CD2 4.1Å; I44-L528 HydrophobicContact CG2-CD2 4.04Å; I44-N558 HydrophobicContact CD1-CB 3.95Å
45M91.6Very high91.9Very high0 Ų052.5 Ų52.50%028%0.277CS..Hα-helixtrans-71.3-21.1-179.7-44.9-65.188.800112.9N38 K41 H42 W43 F108 L110 M116 Y118N38-M45 HydrophobicContact CB-CB 3.84Å; N38-M45 PolarHBondContact N-O 3.3Å; N38-M45 CarbonylContact O-C 3.52Å; K41-M45 HydrophobicContact CB-CB 3.8Å; K41-M45 HydrophobicContact CB-CG 3.8Å; K41-M45 HydrophobicContact CD-CG 4.35Å; H42-M45 PolarHBondContact O-N 2.87Å; W43-M45 VanDerWaalsContact C-N 3.33Å; W43-M45 PolarHBondContact O-N 3.48Å; M45-F108 HydrophobicContact SD-CB 3.84Å; M45-F108 HydrophobicContact SD-CD2 4.28Å; M45-F108 HydrophobicContact SD-CG 4.37Å; M45-L110 HydrophobicContact CE-CD1 3.88Å; M45-L110 HydrophobicContact CE-CD2 3.81Å; M45-L110 HydrophobicContact CE-CG 4.19Å; M45-L110 HydrophobicContact SD-CD1 4.1Å; M45-M116 HydrophobicContact CE-CE 3.76Å; M45-M116 HydrophobicContact CE-SD 3.77Å; M45-Y118 HydrophobicContact CG-CE2 4.39Å; M45-Y118 WeakPolarHBondContact CG-OH 3.35Å; M45-Y118 HydrophobicContact SD-CE2 3.8Å
46Q90.1Very high91.8Very high62 Ų6250.8 Ų50.829%0.2927%0.273SS..Hα-helixtrans-74.7-34.2172.9-53.9177.7-4.400111.3N38 M39 K41 H42 W43 I44N38-Q46 WeakPolarHBondContact O-CG 3.42Å; N38-Q46 PolarHBondContact O-N 3.33Å; M39-Q46 HydrophobicContact CE-CB 4.46Å; M39-Q46 HydrophobicContact SD-CB 4.23Å; K41-Q46 VanDerWaalsContact O-CG 3.27Å; K41-Q46 WeakPolarHBondContact O-CG 3.49Å; K41-Q46 PolarHBondContact O-NE2 3.44Å; H42-Q46 PolarHBondContact O-N 3.27Å; W43-Q46 WeakPolarHBondContact O-CB 3.41Å; W43-Q46 PolarHBondContact O-N 3.04Å; I44-Q46 PolarHBondContact O-N 3.16Å
47Y86.4Confident91.8Very high180 Ų18053.1 Ų53.171%0.70628%0.281SS*.Hα-helixtrans-88.6-21.7176-80.1-74.6000113.7W43 I44 G49W43-Y47 HydrophobicContact CE3-CD2 4.04Å; W43-Y47 HydrophobicContact CE3-CE2 4.42Å; W43-Y47 VanDerWaalsContact O-CD2 3.31Å; W43-Y47 WeakPolarHBondContact O-CD2 3.28Å; W43-Y47 PolarHBondContact O-N 3.05Å; W43-Y47 VanDerWaalsContact O-N 3.15Å; I44-Y47 CarbonylContact O-C 3.42Å; I44-Y47 PolarHBondContact O-N 3.34Å; I44-Y47 VanDerWaalsContact O-N 3.17Å; Y47-G49 PolarHBondContact O-N 3.1Å
48T89.7Confident91.9Very high17 Ų1749.5 Ų49.510%0.10426%0.257CS..  trans-75.4106.8173.3-62.30000109.6P37 I44 F108 L110P37-T48 WeakPolarHBondContact CA-O 3.45Å; I44-T48 WeakPolarHBondContact O-CB 3.26Å; I44-T48 PolarHBondContact O-N 3.14Å; I44-T48 PolarHBondContact O-OG1 2.99Å; T48-F108 VanDerWaalsContact CG2-O 3.23Å; T48-F108 WeakPolarHBondContact CG2-O 3.33Å; T48-L110 HydrophobicContact CG2-CD2 4.25Å
49G90.3Very high92Very high35 Ų3549.4 Ų49.436%0.36126%0.256SS..  trans-79178.8169.400000113Y47Y47-G49 PolarHBondContact O-N 3.1Å
50P94Very high92.2Very high81 Ų8145.2 Ų45.253%0.52624%0.237SC..PPolyproline II helixtrans-60.5147.2174.827.2-35.5000111.7
51M94.2Very high92.2Very high11 Ų1143.3 Ų43.35%0.05423%0.226CC..PPolyproline II helixtrans-63.2133.3174.6-69.3-157.2-69.700111.4Y33 N34 H55 M56 T59 V111Y33-M51 HydrophobicContact CD2-CE 4.16Å; Y33-M51 HydrophobicContact CE1-CE 4.03Å; Y33-M51 HydrophobicContact CE2-CE 3.6Å; N34-M51 HydrophobicContact CB-CE 3.93Å; N34-M51 VanDerWaalsContact OD1-CB 3.32Å; N34-M51 WeakPolarHBondContact OD1-CB 3.05Å; N34-M51 PolarHBondContact OD1-N 2.89Å; M51-H55 HydrophobicContact CB-CB 3.88Å; M51-H55 HydrophobicContact CG-CB 4.13Å; M51-H55 HydrophobicContact SD-CB 4.01Å; M51-M56 HydrophobicContact CB-CG 3.94Å; M51-M56 HydrophobicContact CE-CG 4.07Å; M51-T59 HydrophobicContact SD-CG2 4.3Å; M51-V111 HydrophobicContact SD-CG2 4.48Å
52L93.4Very high92.2Very high100 Ų10043.3 Ų43.352%0.52423%0.226SC..PPolyproline II helixtrans-67.1156.2166.7-57.4178.1000109.8I54 H55 M56L52-I54 HydrophobicContact CB-CG2 3.83Å; L52-I54 HydrophobicContact CD1-CG2 4.43Å; L52-I54 PolarHBondContact O-N 3.42Å; L52-I54 VanDerWaalsContact O-N 3.12Å; L52-H55 WeakPolarHBondContact O-CA 3.03Å; L52-H55 WeakPolarHBondContact O-CB 3.16Å; L52-H55 PolarHBondContact O-N 3.07Å; L52-M56 PolarHBondContact O-N 2.89Å; L52-M56 VanDerWaalsContact O-N 3.14Å
53P94.3Very high92.4Very high106 Ų10644.6 Ų44.669%0.68823%0.232SC*.Hα-helixtrans-53.7-36177.7-28.335.8000113.7H55 M56 E57P53-H55 VanDerWaalsContact C-N 3.34Å; P53-H55 PolarHBondContact O-N 3.32Å; P53-M56 PolarHBondContact O-N 2.9Å; P53-E57 PolarHBondContact O-N 3.43Å
54I92.9Very high92.7Very high40 Ų4044.4 Ų44.421%0.20523%0.232CC..Hα-helixtrans-62.8-34.8173.9-173.3169.2000113.1L52 F58 W544 L546 F549L52-I54 HydrophobicContact CB-CG2 3.83Å; L52-I54 HydrophobicContact CD1-CG2 4.43Å; L52-I54 PolarHBondContact O-N 3.42Å; L52-I54 VanDerWaalsContact O-N 3.12Å; I54-F58 VanDerWaalsContact O-CB 3.32Å; I54-F58 WeakPolarHBondContact O-CB 3.47Å; I54-F58 PolarHBondContact O-N 3.17Å; I54-F58 VanDerWaalsContact O-N 3.09Å; I54-W544 HydrophobicContact CD1-CZ2 4.03Å; I54-W544 HydrophobicContact CG1-CH2 3.9Å; I54-W544 HydrophobicContact CG1-CZ2 3.53Å; I54-W544 WeakPolarHBondContact O-CH2 3.44Å; I54-L546 HydrophobicContact CD1-CB 4.11Å; I54-L546 VanDerWaalsContact CD1-O 3.28Å; I54-L546 WeakPolarHBondContact CD1-O 3.28Å; I54-L546 HydrophobicContact CG1-CB 4.16Å; I54-F549 HydrophobicContact CD1-CB 4.22Å; I54-F549 HydrophobicContact CD1-CD1 4.16Å; I54-F549 HydrophobicContact CG1-CD1 4.15Å
55H94.1Very high92.8Very high26 Ų2644.4 Ų44.412%0.1223%0.232CC..Hα-helixtrans-71.2-39.2174.1-60.7171.7000111M51 L52 P53 F58 T59 V111 F549M51-H55 HydrophobicContact CB-CB 3.88Å; M51-H55 HydrophobicContact CG-CB 4.13Å; M51-H55 HydrophobicContact SD-CB 4.01Å; L52-H55 WeakPolarHBondContact O-CA 3.03Å; L52-H55 WeakPolarHBondContact O-CB 3.16Å; L52-H55 PolarHBondContact O-N 3.07Å; P53-H55 VanDerWaalsContact C-N 3.34Å; P53-H55 PolarHBondContact O-N 3.32Å; H55-F58 WeakPolarHBondContact O-CB 3.33Å; H55-F58 PolarHBondContact O-N 3.48Å; H55-T59 PolarHBondContact O-N 3.02Å; H55-T59 PolarHBondContact O-OG1 2.85Å; H55-T59 VanDerWaalsContact O-OG1 3.05Å; H55-V111 HydrophobicContact CB-CG2 3.98Å; H55-F549 AromaticContact CD2-CD2 3.31Å; H55-F549 WeakPolarHBondContact CD2-CD2 3.25Å; H55-F549 AromaticContact CD2-CE2 3.71Å; H55-F549 AromaticContact CD2-CG 3.92Å; H55-F549 AromaticContact NE2-CD2 3.44Å; H55-F549 WeakPolarHBondContact NE2-CD2 3.36Å
56M94.8Very high92.9Very high67 Ų6746.1 Ų46.133%0.3324%0.238SC..Hα-helixtrans-64.7-42.5178.7-67.3174.264.500112.2Y33 M51 L52 P53 T59 N60Y33-M56 HydrophobicContact CE1-CE 4.32Å; Y33-M56 PolarHBondContact OH-O 3.12Å; M51-M56 HydrophobicContact CB-CG 3.94Å; M51-M56 HydrophobicContact CE-CG 4.07Å; L52-M56 PolarHBondContact O-N 2.89Å; L52-M56 VanDerWaalsContact O-N 3.14Å; P53-M56 PolarHBondContact O-N 2.9Å; M56-T59 VanDerWaalsContact CA-OG1 3.3Å; M56-T59 WeakPolarHBondContact CA-OG1 3.29Å; M56-T59 PolarHBondContact O-N 2.9Å; M56-T59 PolarHBondContact O-OG1 2.77Å; M56-N60 VanDerWaalsContact O-CG 3.25Å; M56-N60 PolarHBondContact O-N 2.87Å; M56-N60 PolarHBondContact O-ND2 2.75Å
57E93.5Very high93.2Very high71 Ų7144.9 Ų44.933%0.33223%0.233SC..Hα-helixtrans-72.5-33.3176.4-171.553.3-157.100111.9P53 T59 N60 I61 L546P53-E57 PolarHBondContact O-N 3.43Å; E57-T59 VanDerWaalsContact C-N 3.35Å; E57-T59 PolarHBondContact O-N 2.85Å; E57-N60 PolarHBondContact O-N 2.92Å; E57-N60 PolarHBondContact OE2-ND2 3.03Å; E57-I61 HydrophobicContact CG-CD1 4.23Å; E57-I61 WeakPolarHBondContact O-CG1 3.27Å; E57-I61 PolarHBondContact O-N 3.45Å; E57-L546 HydrophobicContact CB-CD1 4.06Å; E57-L546 HydrophobicContact CG-CD1 3.95Å
58F93.6Very high93.5Very high0 Ų036.4 Ų36.40%020%0.2CC..Hα-helixtrans-61.3-41.6169.8-176.4-96.5000112.2I54 H55 I61 L62 V111 K112 H533 H537 W538 W544 F549I54-F58 VanDerWaalsContact O-CB 3.32Å; I54-F58 WeakPolarHBondContact O-CB 3.47Å; I54-F58 PolarHBondContact O-N 3.17Å; I54-F58 VanDerWaalsContact O-N 3.09Å; H55-F58 WeakPolarHBondContact O-CB 3.33Å; H55-F58 PolarHBondContact O-N 3.48Å; F58-I61 PolarHBondContact O-N 3.41Å; F58-L62 HydrophobicContact CE1-CB 4.48Å; F58-L62 HydrophobicContact CE1-CD2 4.13Å; F58-L62 WeakPolarHBondContact O-CB 3.5Å; F58-L62 PolarHBondContact O-N 2.98Å; F58-V111 HydrophobicContact CD1-CG1 3.65Å; F58-V111 HydrophobicContact CE1-CG1 4.12Å; F58-K112 HydrophobicContact CE1-CD 4.13Å; F58-H533 HydrophobicContact CE2-CB 4.35Å; F58-H533 AromaticContact CZ-CE1 3.76Å; F58-H533 AromaticContact CZ-CG 3.8Å; F58-H533 AromaticContact CZ-ND1 3.58Å; F58-H537 AromaticContact CE2-CD2 3.81Å; F58-H537 AromaticContact CZ-CD2 3.94Å; F58-W538 AromaticContact CD2-CH2 3.66Å; F58-W538 HydrophobicContact CD2-CH2 3.66Å; F58-W538 HydrophobicContact CD2-CZ2 4.45Å; F58-W538 HydrophobicContact CD2-CZ3 4.17Å; F58-W538 AromaticContact CE2-CH2 3.48Å; F58-W538 HydrophobicContact CE2-CH2 3.48Å; F58-W538 VanDerWaalsContact CE2-CH2 3.48Å; F58-W538 AromaticContact CE2-CZ2 3.85Å; F58-W538 HydrophobicContact CE2-CZ2 3.85Å; F58-W538 HydrophobicContact CE2-CZ3 4.11Å; F58-W538 HydrophobicContact CG-CH2 4.44Å; F58-W538 HydrophobicContact CZ-CH2 4.15Å; F58-W538 HydrophobicContact CZ-CZ2 4.13Å; F58-W544 HydrophobicContact CB-CH2 3.57Å; F58-W544 HydrophobicContact CB-CZ2 4.15Å; F58-W544 HydrophobicContact CB-CZ3 3.87Å; F58-W544 HydrophobicContact CD2-CD2 4.1Å; F58-W544 HydrophobicContact CD2-CE3 4.04Å; F58-W544 HydrophobicContact CD2-CH2 4.15Å; F58-W544 HydrophobicContact CD2-CZ2 4.19Å; F58-W544 HydrophobicContact CD2-CZ3 4.07Å; F58-W544 HydrophobicContact CG-CH2 4.37Å; F58-W544 HydrophobicContact CG-CZ3 4.48Å; F58-F549 HydrophobicContact CB-CE1 3.98Å; F58-F549 HydrophobicContact CB-CZ 3.86Å; F58-F549 HydrophobicContact CD1-CE1 4.38Å; F58-F549 AromaticContact CD1-CZ 3.64Å; F58-F549 HydrophobicContact CD1-CZ 3.64Å; F58-F549 AromaticContact CD2-CE1 3.63Å; F58-F549 HydrophobicContact CD2-CE1 3.63Å; F58-F549 AromaticContact CD2-CZ 3.7Å; F58-F549 HydrophobicContact CD2-CZ 3.7Å; F58-F549 HydrophobicContact CE1-CZ 4.01Å; F58-F549 HydrophobicContact CE2-CE1 4.17Å; F58-F549 HydrophobicContact CE2-CZ 4.1Å; F58-F549 AromaticContact CG-CE1 3.74Å; F58-F549 HydrophobicContact CG-CE1 3.74Å; F58-F549 AromaticContact CG-CZ 3.44Å; F58-F549 HydrophobicContact CG-CZ 3.44Å; F58-F549 VanDerWaalsContact CG-CZ 3.44Å; F58-F549 HydrophobicContact CZ-CZ 4.23Å
59T94.7Very high93.7Very high0 Ų036.2 Ų36.20%020%0.199CC..Hα-helixtrans-66.8-38.9176.640.50000112.8Y33 M51 H55 M56 E57 L62 Q63 I105 V111Y33-T59 PolarHBondContact OH-OG1 3.11Å; M51-T59 HydrophobicContact SD-CG2 4.3Å; H55-T59 PolarHBondContact O-N 3.02Å; H55-T59 PolarHBondContact O-OG1 2.85Å; H55-T59 VanDerWaalsContact O-OG1 3.05Å; M56-T59 VanDerWaalsContact CA-OG1 3.3Å; M56-T59 WeakPolarHBondContact CA-OG1 3.29Å; M56-T59 PolarHBondContact O-N 2.9Å; M56-T59 PolarHBondContact O-OG1 2.77Å; E57-T59 VanDerWaalsContact C-N 3.35Å; E57-T59 PolarHBondContact O-N 2.85Å; T59-L62 PolarHBondContact O-N 3.42Å; T59-Q63 PolarHBondContact O-N 2.82Å; T59-I105 HydrophobicContact CG2-CG2 3.63Å; T59-V111 HydrophobicContact CG2-CG1 4.13Å; T59-V111 WeakPolarHBondContact CG2-O 3.48Å
60N93.8Very high94Very high44 Ų4437.4 Ų37.424%0.23520%0.196CC..Hα-helixtrans-57-52.9172.2-69.7-25.5000111.8H28 M56 E57 Q63 R64H28-N60 PolarHBondContact CE1-OD1 3.31Å; M56-N60 VanDerWaalsContact O-CG 3.25Å; M56-N60 PolarHBondContact O-N 2.87Å; M56-N60 PolarHBondContact O-ND2 2.75Å; E57-N60 PolarHBondContact O-N 2.92Å; E57-N60 PolarHBondContact OE2-ND2 3.03Å; N60-Q63 PolarHBondContact O-N 2.56Å; N60-R64 PolarHBondContact O-N 3.32Å
61I92.8Very high94Very high11 Ų1135.2 Ų35.26%0.05618%0.18CC..Hα-helixtrans-67.7-40.3-179.3-60.7173.7000110.5E57 F58 Q63 R64 K65 W538 P542 W544E57-I61 HydrophobicContact CG-CD1 4.23Å; E57-I61 WeakPolarHBondContact O-CG1 3.27Å; E57-I61 PolarHBondContact O-N 3.45Å; F58-I61 PolarHBondContact O-N 3.41Å; I61-Q63 PolarHBondContact O-N 3.32Å; I61-R64 WeakPolarHBondContact O-CB 3.39Å; I61-R64 PolarHBondContact O-N 3.43Å; I61-K65 HydrophobicContact CG2-CG 4.06Å; I61-K65 WeakPolarHBondContact O-CB 3.39Å; I61-K65 VanDerWaalsContact O-CG 3.27Å; I61-K65 WeakPolarHBondContact O-CG 3.39Å; I61-K65 PolarHBondContact O-N 3.41Å; I61-W538 HydrophobicContact CB-CH2 3.91Å; I61-W538 HydrophobicContact CB-CZ3 3.91Å; I61-W538 HydrophobicContact CG2-CE3 3.94Å; I61-W538 HydrophobicContact CG2-CH2 3.62Å; I61-W538 HydrophobicContact CG2-CZ2 4.42Å; I61-W538 HydrophobicContact CG2-CZ3 3.33Å; I61-P542 HydrophobicContact CG2-CG 3.81Å; I61-W544 HydrophobicContact CD1-CE3 4.11Å; I61-W544 HydrophobicContact CD1-CZ3 4.05Å
62L93.8Very high94.1Very high0 Ų036.6 Ų36.60%019%0.191CC..Hα-helixtrans-59-43.5176.7175.766.5000112.3E12 F58 T59 K65 R66 I105 K112 W538E12-L62 HydrophobicContact CB-CD1 4.37Å; E12-L62 HydrophobicContact CG-CD1 3.7Å; E12-L62 WeakPolarHBondContact OE1-CD1 3.49Å; F58-L62 HydrophobicContact CE1-CB 4.48Å; F58-L62 HydrophobicContact CE1-CD2 4.13Å; F58-L62 WeakPolarHBondContact O-CB 3.5Å; F58-L62 PolarHBondContact O-N 2.98Å; T59-L62 PolarHBondContact O-N 3.42Å; L62-K65 PolarHBondContact O-N 2.92Å; L62-R66 HydrophobicContact CD1-CG 4.12Å; L62-R66 HydrophobicContact CG-CG 4.45Å; L62-R66 WeakPolarHBondContact O-CB 3.26Å; L62-R66 VanDerWaalsContact O-CG 3.23Å; L62-R66 WeakPolarHBondContact O-CG 3.49Å; L62-R66 PolarHBondContact O-N 2.76Å; L62-I105 HydrophobicContact CD2-CG1 4.43Å; L62-I105 HydrophobicContact CD2-CG2 4.29Å; L62-K112 HydrophobicContact CD1-CD 4.21Å; L62-K112 HydrophobicContact CD2-CB 3.65Å; L62-K112 HydrophobicContact CD2-CD 3.46Å; L62-K112 VanDerWaalsContact CD2-CD 3.46Å; L62-K112 HydrophobicContact CD2-CG 4.22Å; L62-W538 HydrophobicContact CB-CH2 4.37Å; L62-W538 HydrophobicContact CB-CZ2 4.08Å; L62-W538 HydrophobicContact CD1-CZ2 4.13Å
63Q94.7Very high94.2Very high27 Ų2732.1 Ų32.113%0.12617%0.168CC..Hα-helixtrans-65.4-44.4177.5174.960.42.500111.3A25 H28 T59 N60 I61 K65 R66 L67 I105A25-Q63 HydrophobicContact CB-CG 4.13Å; A25-Q63 WeakPolarHBondContact O-CG 3.46Å; H28-Q63 HydrophobicContact CB-CB 4.25Å; H28-Q63 HydrophobicContact CB-CG 3.97Å; H28-Q63 WeakPolarHBondContact ND1-CB 3.44Å; T59-Q63 PolarHBondContact O-N 2.82Å; N60-Q63 PolarHBondContact O-N 2.56Å; I61-Q63 PolarHBondContact O-N 3.32Å; Q63-K65 PolarHBondContact O-N 3.02Å; Q63-R66 PolarHBondContact O-N 3.44Å; Q63-L67 WeakPolarHBondContact O-CG 3.23Å; Q63-L67 PolarHBondContact O-N 2.94Å; Q63-L67 VanDerWaalsContact O-N 3.15Å; Q63-I105 HydrophobicContact CB-CD1 4.25Å
64R93.6Very high94.3Very high55 Ų5531.9 Ų31.921%0.20816%0.16CC..Hα-helixtrans-54.1-55172.6177.5-175.2-51.4131.4-0.2110.7Y22 P23 A25 N60 I61 R66 L67 Q68Y22-R64 WeakPolarHBondContact O-CG 3.3Å; P23-R64 VanDerWaalsContact O-CZ 3.27Å; P23-R64 PolarHBondContact O-NE 3.07Å; P23-R64 PolarHBondContact O-NH2 3.43Å; A25-R64 HydrophobicContact CB-CB 4.11Å; N60-R64 PolarHBondContact O-N 3.32Å; I61-R64 WeakPolarHBondContact O-CB 3.39Å; I61-R64 PolarHBondContact O-N 3.43Å; R64-R66 PolarHBondContact O-N 2.94Å; R64-L67 PolarHBondContact O-N 3.37Å; R64-Q68 HydrophobicContact CG-CG 4.38Å; R64-Q68 VanDerWaalsContact O-CG 3.29Å; R64-Q68 WeakPolarHBondContact O-CG 3.44Å; R64-Q68 PolarHBondContact O-N 3Å
65K93Very high94.4Very high0 Ų032 Ų320%016%0.161CC..Hα-helixtrans-53.9-47.8178.6-77.6-61.7-154.8176.60112.6E12 D13 I61 L62 Q63 L67 Q68 T69 W538 T540 A541 P542E12-K65 HydrophobicContact CB-CB 3.94Å; E12-K65 WeakPolarHBondContact O-CB 3.25Å; E12-K65 WeakPolarHBondContact O-CD 3.31Å; D13-K65 IonicContact OD1-NZ 3.98Å; I61-K65 HydrophobicContact CG2-CG 4.06Å; I61-K65 WeakPolarHBondContact O-CB 3.39Å; I61-K65 VanDerWaalsContact O-CG 3.27Å; I61-K65 WeakPolarHBondContact O-CG 3.39Å; I61-K65 PolarHBondContact O-N 3.41Å; L62-K65 PolarHBondContact O-N 2.92Å; Q63-K65 PolarHBondContact O-N 3.02Å; K65-L67 VanDerWaalsContact C-N 3.35Å; K65-L67 PolarHBondContact O-N 3.11Å; K65-Q68 PolarHBondContact O-N 3.08Å; K65-T69 PolarHBondContact O-N 3.35Å; K65-T69 PolarHBondContact O-OG1 2.8Å; K65-W538 HydrophobicContact CG-CD2 4.15Å; K65-W538 HydrophobicContact CG-CZ2 4.19Å; K65-T540 VanDerWaalsContact NZ-C 3.31Å; K65-T540 PolarHBondContact NZ-O 3.42Å; K65-T540 PolarHBondContact NZ-OG1 2.7Å; K65-A541 PolarHBondContact NZ-O 3.11Å; K65-P542 WeakPolarHBondContact CE-O 3.5Å; K65-P542 PolarHBondContact NZ-O 3.31Å
66R94.2Very high94.5Very high36 Ų3632.5 Ų32.514%0.13617%0.168CC..Hα-helixtrans-60.2-41.3179.4-75.1171.661.177-4.4112.7P8 E12 L62 Q63 R64 L70 Y103P8-R66 HydrophobicContact CB-CB 4.15Å; P8-R66 HydrophobicContact CB-CG 4.32Å; P8-R66 WeakPolarHBondContact CB-O 3.45Å; P8-R66 PolarHBondContact O-NH1 3.1Å; E12-R66 HydrophobicContact CB-CG 4.36Å; E12-R66 HydrophobicContact CG-CG 3.87Å; L62-R66 HydrophobicContact CD1-CG 4.12Å; L62-R66 HydrophobicContact CG-CG 4.45Å; L62-R66 WeakPolarHBondContact O-CB 3.26Å; L62-R66 VanDerWaalsContact O-CG 3.23Å; L62-R66 WeakPolarHBondContact O-CG 3.49Å; L62-R66 PolarHBondContact O-N 2.76Å; Q63-R66 PolarHBondContact O-N 3.44Å; R64-R66 PolarHBondContact O-N 2.94Å; R66-L70 WeakPolarHBondContact O-CB 3.34Å; R66-L70 PolarHBondContact O-N 3.21Å; R66-Y103 VanDerWaalsContact NH2-CD1 3.34Å; R66-Y103 VanDerWaalsContact NH2-CG 3.3Å
67L94.6Very high94.6Very high36 Ų3631.7 Ų31.719%0.18817%0.167CC..Hα-helixtrans-67-43.1174.3-64.2175.3000111.8Y22 A25 Q63 R64 K65 T69 L70 M71Y22-L67 HydrophobicContact CD1-CB 4.45Å; Y22-L67 HydrophobicContact CD1-CD1 4.04Å; Y22-L67 HydrophobicContact CD2-CB 3.48Å; Y22-L67 VanDerWaalsContact CD2-CB 3.48Å; Y22-L67 HydrophobicContact CD2-CD1 4.45Å; Y22-L67 HydrophobicContact CE2-CB 3.77Å; Y22-L67 HydrophobicContact CG-CB 3.86Å; Y22-L67 HydrophobicContact CG-CD1 3.97Å; A25-L67 HydrophobicContact CB-CD1 3.92Å; Q63-L67 WeakPolarHBondContact O-CG 3.23Å; Q63-L67 PolarHBondContact O-N 2.94Å; Q63-L67 VanDerWaalsContact O-N 3.15Å; R64-L67 PolarHBondContact O-N 3.37Å; K65-L67 VanDerWaalsContact C-N 3.35Å; K65-L67 PolarHBondContact O-N 3.11Å; L67-T69 VanDerWaalsContact C-N 3.34Å; L67-T69 PolarHBondContact O-N 2.69Å; L67-L70 WeakPolarHBondContact O-CB 3.49Å; L67-L70 PolarHBondContact O-N 2.83Å; L67-L70 VanDerWaalsContact O-N 3.17Å; L67-M71 PolarHBondContact O-N 3.03Å
68Q94.1Very high94.7Very high2 Ų233.7 Ų33.71%0.00918%0.176CC..Hα-helixtrans-62.2-37.7176.4-65174.6-22.200112.7S14 F18 S19 L21 Y22 R64 K65S14-Q68 VanDerWaalsContact CB-CB 3.5Å; F18-Q68 HydrophobicContact CB-CB 4.47Å; F18-Q68 WeakPolarHBondContact CB-O 3.25Å; F18-Q68 WeakPolarHBondContact O-CG 3.4Å; S19-Q68 VanDerWaalsContact C-NE2 3.34Å; S19-Q68 PolarHBondContact O-NE2 2.78Å; L21-Q68 HydrophobicContact CB-CG 4.39Å; L21-Q68 PolarHBondContact O-NE2 3.44Å; Y22-Q68 HydrophobicContact CD2-CG 4.25Å; R64-Q68 HydrophobicContact CG-CG 4.38Å; R64-Q68 VanDerWaalsContact O-CG 3.29Å; R64-Q68 WeakPolarHBondContact O-CG 3.44Å; R64-Q68 PolarHBondContact O-N 3Å; K65-Q68 PolarHBondContact O-N 3.08Å
69T94.5Very high94.9Very high12 Ų1241.5 Ų41.57%0.07421%0.206CC..Hα-helixtrans-73.8-30.4174.5-46.50000112A7 E12 D13 K65 L67 M71 S72A7-T69 HydrophobicContact CB-CG2 3.73Å; E12-T69 PolarHBondContact O-OG1 2.92Å; D13-T69 WeakPolarHBondContact O-CG2 3.4Å; D13-T69 PolarHBondContact O-OG1 3.38Å; K65-T69 PolarHBondContact O-N 3.35Å; K65-T69 PolarHBondContact O-OG1 2.8Å; L67-T69 VanDerWaalsContact C-N 3.34Å; L67-T69 PolarHBondContact O-N 2.69Å; T69-M71 VanDerWaalsContact C-N 3.3Å; T69-M71 PolarHBondContact O-N 3.42Å; T69-S72 WeakPolarHBondContact O-CB 3.41Å; T69-S72 PolarHBondContact O-N 3.32Å
70L95Very high94.9Very high60 Ų6043.3 Ų43.331%0.31422%0.215SC..Hα-helixtrans-67.1-28.6177.5-171.266000112.5P8 R66 L67 S72 V73 D74P8-L70 HydrophobicContact CG-CD1 4.47Å; R66-L70 WeakPolarHBondContact O-CB 3.34Å; R66-L70 PolarHBondContact O-N 3.21Å; L67-L70 WeakPolarHBondContact O-CB 3.49Å; L67-L70 PolarHBondContact O-N 2.83Å; L67-L70 VanDerWaalsContact O-N 3.17Å; L70-S72 PolarHBondContact O-N 2.83Å; L70-V73 HydrophobicContact CD1-CB 4.16Å; L70-V73 HydrophobicContact CD1-CG2 4.16Å; L70-V73 WeakPolarHBondContact O-CA 3.03Å; L70-V73 VanDerWaalsContact O-CB 3.26Å; L70-V73 WeakPolarHBondContact O-CB 3.03Å; L70-V73 PolarHBondContact O-N 3.32Å; L70-D74 PolarHBondContact O-N 3.37Å
71M95.4Very high95.1Very high35 Ų3545.6 Ų45.617%0.17222%0.221CC..Hα-helixtrans-56.8-33.1173-67.3-52.7-53.100113.2F18 L21 Y22 L67 T69 V73 D74 D75F18-M71 HydrophobicContact CB-CB 4.23Å; F18-M71 HydrophobicContact CD1-CB 3.61Å; F18-M71 HydrophobicContact CD1-CG 4.11Å; F18-M71 HydrophobicContact CD2-CB 3.6Å; F18-M71 HydrophobicContact CE1-CB 3.76Å; F18-M71 HydrophobicContact CE2-CB 3.75Å; F18-M71 HydrophobicContact CG-CB 3.53Å; F18-M71 HydrophobicContact CG-CG 4.21Å; F18-M71 HydrophobicContact CZ-CB 3.83Å; L21-M71 HydrophobicContact CD1-CG 3.88Å; Y22-M71 HydrophobicContact CE2-CG 3.98Å; Y22-M71 HydrophobicContact CE2-SD 4.13Å; Y22-M71 PolarHBondContact OH-SD 2.93Å; L67-M71 PolarHBondContact O-N 3.03Å; T69-M71 VanDerWaalsContact C-N 3.3Å; T69-M71 PolarHBondContact O-N 3.42Å; M71-V73 PolarHBondContact O-N 2.84Å; M71-D74 HydrophobicContact CE-CB 4.22Å; M71-D74 WeakPolarHBondContact O-CB 3.34Å; M71-D74 PolarHBondContact O-N 2.91Å; M71-D74 VanDerWaalsContact O-N 3.17Å; M71-D75 WeakPolarHBondContact O-CB 3.33Å; M71-D75 PolarHBondContact O-N 3.41Å
72S94.5Very high95.3Very high41 Ų4148 Ų4829%0.28723%0.234SC..Hα-helixtrans-68.1-17.5173.6-55.60000113.7F18 T69 L70 S76F18-S72 WeakPolarHBondContact CE2-OG 3.49Å; T69-S72 WeakPolarHBondContact O-CB 3.41Å; T69-S72 PolarHBondContact O-N 3.32Å; L70-S72 PolarHBondContact O-N 2.83Å; S72-S76 WeakPolarHBondContact O-CB 3.31Å
73V95.8Very high95.5Very high6 Ų651.8 Ų51.84%0.03625%0.252CS..Hα-helixtrans-84.4-40.8170.5-174.40000109.7H5 A7 L70 M71 S76 V77 Y97H5-V73 HydrophobicContact CB-CG1 4.33Å; H5-V73 HydrophobicContact CB-CG2 3.93Å; A7-V73 HydrophobicContact CB-CG2 3.62Å; L70-V73 HydrophobicContact CD1-CB 4.16Å; L70-V73 HydrophobicContact CD1-CG2 4.16Å; L70-V73 WeakPolarHBondContact O-CA 3.03Å; L70-V73 VanDerWaalsContact O-CB 3.26Å; L70-V73 WeakPolarHBondContact O-CB 3.03Å; L70-V73 PolarHBondContact O-N 3.32Å; M71-V73 PolarHBondContact O-N 2.84Å; V73-S76 CarbonylContact O-C 3.55Å; V73-S76 WeakPolarHBondContact O-CA 3.39Å; V73-S76 WeakPolarHBondContact O-CB 3.21Å; V73-S76 PolarHBondContact O-N 3.47Å; V73-V77 WeakPolarHBondContact O-CG2 3.23Å; V73-V77 PolarHBondContact O-N 2.96Å; V73-Y97 HydrophobicContact CG1-CE2 4.41Å
74D96.3Very high95.6Very high100 Ų10051.3 Ų51.354%0.53525%0.251SS..Hα-helixtrans-59.1-52.7177.2-151.153000111.3L70 M71 S76 V77 E78L70-D74 PolarHBondContact O-N 3.37Å; M71-D74 HydrophobicContact CE-CB 4.22Å; M71-D74 WeakPolarHBondContact O-CB 3.34Å; M71-D74 PolarHBondContact O-N 2.91Å; M71-D74 VanDerWaalsContact O-N 3.17Å; D74-S76 PolarHBondContact O-N 2.82Å; D74-S76 VanDerWaalsContact O-N 3.12Å; D74-V77 PolarHBondContact O-N 3.24Å; D74-E78 PolarHBondContact O-N 2.97Å
75D95.9Very high95.8Very high42 Ų4252.4 Ų52.423%0.22526%0.263CS..Hα-helixtrans-48.8-39.2169.4-122.277.8000112.1F18 M71 R79F18-D75 WeakPolarHBondContact CZ-OD1 3.43Å; M71-D75 WeakPolarHBondContact O-CB 3.33Å; M71-D75 PolarHBondContact O-N 3.41Å; D75-R79 WeakPolarHBondContact O-CB 3.28Å; D75-R79 WeakPolarHBondContact O-CD 3.49Å; D75-R79 WeakPolarHBondContact O-CG 3.18Å; D75-R79 PolarHBondContact O-N 3.32Å; D75-R79 VanDerWaalsContact O-N 3.08Å; D75-R79 IonicContact OD2-CZ 3.85Å; D75-R79 IonicContact OD2-NE 3.88Å; D75-R79 PolarHBondContact OD2-NE 2.73Å; D75-R79 VanDerWaalsContact OD2-NE 3.09Å; D75-R79 IonicContact OD2-NH2 3.92Å; D75-R79 PolarHBondContact OD2-NH2 2.93Å
76S95.7Very high96Very high38 Ų3860.1 Ų60.127%0.26630%0.299SS..Hα-helixtrans-80.2-22.1-178-179.40000113.3H5 S72 V73 D74 L80H5-S76 VanDerWaalsContact NE2-CB 3.29Å; H5-S76 WeakPolarHBondContact NE2-CB 3.42Å; H5-S76 PolarHBondContact NE2-OG 3.08Å; S72-S76 WeakPolarHBondContact O-CB 3.31Å; V73-S76 CarbonylContact O-C 3.55Å; V73-S76 WeakPolarHBondContact O-CA 3.39Å; V73-S76 WeakPolarHBondContact O-CB 3.21Å; V73-S76 PolarHBondContact O-N 3.47Å; D74-S76 PolarHBondContact O-N 2.82Å; D74-S76 VanDerWaalsContact O-N 3.12Å; S76-L80 WeakPolarHBondContact O-CB 3.48Å; S76-L80 PolarHBondContact O-N 3.24Å
77V96.4Very high96.2Very high50 Ų5062.3 Ų62.330%0.30332%0.317SS..Hα-helixtrans-82.9-41.3172.9171.10000109.7V73 D74 L80 Y81 Y97V73-V77 WeakPolarHBondContact O-CG2 3.23Å; V73-V77 PolarHBondContact O-N 2.96Å; D74-V77 PolarHBondContact O-N 3.24Å; V77-L80 WeakPolarHBondContact O-CB 3.48Å; V77-L80 PolarHBondContact O-N 2.94Å; V77-Y81 WeakPolarHBondContact O-CB 3.28Å; V77-Y81 PolarHBondContact O-N 3.28Å; V77-Y97 HydrophobicContact CG2-CD2 4.22Å; V77-Y97 HydrophobicContact CG2-CE2 4.15Å
78E97.1Very high96.3Very high113 Ų11363.5 Ų63.553%0.52834%0.338SS..Hα-helixtrans-59-50.4173.1-174.3-172.4-133.700111.2D74 L80 Y81 N82D74-E78 PolarHBondContact O-N 2.97Å; E78-L80 VanDerWaalsContact C-N 3.28Å; E78-L80 PolarHBondContact O-N 3.34Å; E78-Y81 PolarHBondContact O-N 3.27Å; E78-Y81 VanDerWaalsContact O-N 3.12Å; E78-N82 WeakPolarHBondContact O-CB 3.46Å; E78-N82 PolarHBondContact O-N 3.31Å
79R96.7Very high96.4Very high164 Ų16467.8 Ų67.862%0.61936%0.358SS*.Hα-helixtrans-59.8-36.4177.3-70.3164-166.2-83.1-2.2113D75 M83D75-R79 WeakPolarHBondContact O-CB 3.28Å; D75-R79 WeakPolarHBondContact O-CD 3.49Å; D75-R79 WeakPolarHBondContact O-CG 3.18Å; D75-R79 PolarHBondContact O-N 3.32Å; D75-R79 VanDerWaalsContact O-N 3.08Å; D75-R79 IonicContact OD2-CZ 3.85Å; D75-R79 IonicContact OD2-NE 3.88Å; D75-R79 PolarHBondContact OD2-NE 2.73Å; D75-R79 VanDerWaalsContact OD2-NE 3.09Å; D75-R79 IonicContact OD2-NH2 3.92Å; D75-R79 PolarHBondContact OD2-NH2 2.93Å; R79-M83 WeakPolarHBondContact O-CB 3.49Å; R79-M83 PolarHBondContact O-N 2.94Å; R79-M83 VanDerWaalsContact O-N 3.13Å
80L96.1Very high96.4Very high37 Ų3767.7 Ų67.719%0.19436%0.357CS..Hα-helixtrans-67.1-44.6174.8172.364.7000111.3M1 I3 S76 V77 E78 M83 L84M1-L80 HydrophobicContact CE-CD1 3.53Å; I3-L80 HydrophobicContact CD1-CD1 4.46Å; I3-L80 HydrophobicContact CD1-CD2 4.09Å; S76-L80 WeakPolarHBondContact O-CB 3.48Å; S76-L80 PolarHBondContact O-N 3.24Å; V77-L80 WeakPolarHBondContact O-CB 3.48Å; V77-L80 PolarHBondContact O-N 2.94Å; E78-L80 VanDerWaalsContact C-N 3.28Å; E78-L80 PolarHBondContact O-N 3.34Å; L80-M83 HydrophobicContact CD1-CE 3.89Å; L80-L84 HydrophobicContact CD1-CD1 4.35Å; L80-L84 HydrophobicContact CG-CD1 4.41Å; L80-L84 WeakPolarHBondContact O-CG 3.45Å; L80-L84 PolarHBondContact O-N 3.4Å
81Y96.7Very high96.4Very high92 Ų9270.9 Ų70.936%0.36137%0.37SS..Hα-helixtrans-63.8-49.1178.5178.6-91.1000111.4V77 E78 M83 L84 V85 L90 I95V77-Y81 WeakPolarHBondContact O-CB 3.28Å; V77-Y81 PolarHBondContact O-N 3.28Å; E78-Y81 PolarHBondContact O-N 3.27Å; E78-Y81 VanDerWaalsContact O-N 3.12Å; Y81-M83 VanDerWaalsContact C-N 3.35Å; Y81-M83 PolarHBondContact O-N 2.92Å; Y81-L84 WeakPolarHBondContact O-CA 3.33Å; Y81-L84 WeakPolarHBondContact O-CB 3.38Å; Y81-L84 PolarHBondContact O-N 3.11Å; Y81-V85 HydrophobicContact CD1-CG2 4.14Å; Y81-V85 HydrophobicContact CE1-CG2 3.76Å; Y81-V85 PolarHBondContact O-N 3.27Å; Y81-L90 HydrophobicContact CD2-CD1 3.85Å; Y81-L90 HydrophobicContact CD2-CD2 4.31Å; Y81-L90 HydrophobicContact CE1-CD2 4.4Å; Y81-L90 HydrophobicContact CE2-CD1 3.74Å; Y81-L90 HydrophobicContact CE2-CD2 3.54Å; Y81-L90 HydrophobicContact CE2-CG 4.29Å; Y81-I95 HydrophobicContact CD2-CD1 4.33Å
82N97.9Very high96.3Very high62 Ų6274.8 Ų74.833%0.33239%0.391SS..Hα-helixtrans-62.3-40.2179.6-69.5-12.8000111.7E78 L84 V85 E86E78-N82 WeakPolarHBondContact O-CB 3.46Å; E78-N82 PolarHBondContact O-N 3.31Å; N82-L84 VanDerWaalsContact C-N 3.3Å; N82-L84 PolarHBondContact O-N 3.06Å; N82-V85 WeakPolarHBondContact O-CB 3.5Å; N82-V85 PolarHBondContact O-N 3.42Å; N82-V85 VanDerWaalsContact O-N 3.08Å; N82-E86 WeakPolarHBondContact O-CB 3.39Å; N82-E86 VanDerWaalsContact O-CG 3.32Å; N82-E86 WeakPolarHBondContact O-CG 3.42Å; N82-E86 PolarHBondContact O-N 3.11Å
83M97.1Very high96.4Very high79 Ų7974.6 Ų74.639%0.38939%0.389SS..Hα-helixtrans-61.7-35.8173.3179.3-85.1-6500112.7R79 L80 Y81 T87R79-M83 WeakPolarHBondContact O-CB 3.49Å; R79-M83 PolarHBondContact O-N 2.94Å; R79-M83 VanDerWaalsContact O-N 3.13Å; L80-M83 HydrophobicContact CD1-CE 3.89Å; Y81-M83 VanDerWaalsContact C-N 3.35Å; Y81-M83 PolarHBondContact O-N 2.92Å; M83-T87 WeakPolarHBondContact O-CB 3.47Å; M83-T87 WeakPolarHBondContact O-CG2 3.34Å; M83-T87 PolarHBondContact O-N 2.77Å; M83-T87 PolarHBondContact O-OG1 2.71Å; M83-T87 HydrophobicContact SD-CG2 4.27Å
84L96.9Very high96.4Very high18 Ų1877.5 Ų77.59%0.09440%0.4CS..Hα-helixtrans-71.4-28.9173.7-69.8168.8000112.9L80 Y81 N82 G88 E89 L90 T93 I95L80-L84 HydrophobicContact CD1-CD1 4.35Å; L80-L84 HydrophobicContact CG-CD1 4.41Å; L80-L84 WeakPolarHBondContact O-CG 3.45Å; L80-L84 PolarHBondContact O-N 3.4Å; Y81-L84 WeakPolarHBondContact O-CA 3.33Å; Y81-L84 WeakPolarHBondContact O-CB 3.38Å; Y81-L84 PolarHBondContact O-N 3.11Å; N82-L84 VanDerWaalsContact C-N 3.3Å; N82-L84 PolarHBondContact O-N 3.06Å; L84-G88 PolarHBondContact O-N 2.89Å; L84-E89 HydrophobicContact CD2-CB 4.17Å; L84-E89 PolarHBondContact O-N 3.24Å; L84-E89 VanDerWaalsContact O-N 3.13Å; L84-L90 HydrophobicContact CB-CB 4.05Å; L84-L90 HydrophobicContact CB-CD1 4.06Å; L84-L90 HydrophobicContact CD1-CD1 4.45Å; L84-L90 WeakPolarHBondContact O-CB 3.42Å; L84-L90 PolarHBondContact O-N 2.85Å; L84-T93 HydrophobicContact CD1-CG2 3.93Å; L84-T93 HydrophobicContact CD2-CG2 4.33Å; L84-I95 HydrophobicContact CD1-CD1 3.81Å; L84-I95 HydrophobicContact CD1-CG1 4.26Å
85V97.3Very high96.4Very high77 Ų7774.7 Ų74.747%0.46738%0.384SS..Hα-helixtrans-68.9-52.1169.7176.40000110.3Y81 N82 T87 G88 L90Y81-V85 HydrophobicContact CD1-CG2 4.14Å; Y81-V85 HydrophobicContact CE1-CG2 3.76Å; Y81-V85 PolarHBondContact O-N 3.27Å; N82-V85 WeakPolarHBondContact O-CB 3.5Å; N82-V85 PolarHBondContact O-N 3.42Å; N82-V85 VanDerWaalsContact O-N 3.08Å; V85-T87 VanDerWaalsContact C-N 3.28Å; V85-T87 PolarHBondContact O-N 2.86Å; V85-G88 PolarHBondContact O-N 2.88Å; V85-L90 HydrophobicContact CG2-CD2 3.63Å
86E97.8Very high96.4Very high162 Ų16275 Ų7576%0.75739%0.385SS*.Hα-helixtrans-61.3-33.4-177.4-72.1166.7-163.700113N82N82-E86 WeakPolarHBondContact O-CB 3.39Å; N82-E86 VanDerWaalsContact O-CG 3.32Å; N82-E86 WeakPolarHBondContact O-CG 3.42Å; N82-E86 PolarHBondContact O-N 3.11Å
87T97.4Very high96.5Very high83 Ų8377.4 Ų77.451%0.50939%0.389SS..THydrogen-bonded Turntrans-86.7-9175.153.60000114.2M83 V85 E89M83-T87 WeakPolarHBondContact O-CB 3.47Å; M83-T87 WeakPolarHBondContact O-CG2 3.34Å; M83-T87 PolarHBondContact O-N 2.77Å; M83-T87 PolarHBondContact O-OG1 2.71Å; M83-T87 HydrophobicContact SD-CG2 4.27Å; V85-T87 VanDerWaalsContact C-N 3.28Å; V85-T87 PolarHBondContact O-N 2.86Å; T87-E89 PolarHBondContact O-N 2.91Å
88G97Very high96.4Very high60 Ų6077.3 Ų77.362%0.61939%0.388SS*.SBendtrans76.2-1.3-177.500000115.7L84 V85 L90L84-G88 PolarHBondContact O-N 2.89Å; V85-G88 PolarHBondContact O-N 2.88Å; G88-L90 VanDerWaalsContact C-N 3.32Å; G88-L90 PolarHBondContact O-N 3.45Å
89E96.5Very high96.4Very high92 Ų9273.5 Ų73.543%0.4338%0.376SS..G310 helixtrans-81.6-3.8-176.7-71.7-70.9174.900114L84 T87 E91 N92 T93L84-E89 HydrophobicContact CD2-CB 4.17Å; L84-E89 PolarHBondContact O-N 3.24Å; L84-E89 VanDerWaalsContact O-N 3.13Å; T87-E89 PolarHBondContact O-N 2.91Å; E89-E91 PolarHBondContact O-N 2.75Å; E89-N92 WeakPolarHBondContact O-CB 3.38Å; E89-N92 PolarHBondContact O-N 3.26Å; E89-N92 VanDerWaalsContact O-N 3.11Å; E89-N92 WeakPolarHBondContact OE2-CB 3.37Å; E89-N92 PolarHBondContact OE2-ND2 2.93Å; E89-T93 WeakPolarHBondContact O-CB 3.48Å; E89-T93 PolarHBondContact O-N 2.98Å; E89-T93 VanDerWaalsContact O-N 3.1Å; E89-T93 PolarHBondContact O-OG1 3.01Å
90L95.1Very high96.2Very high10 Ų1071.1 Ų71.15%0.05238%0.376CS..G310 helixtrans-56.9-44.5-176.7-178.463.8000113.6Y81 L84 V85 G88 N92 T93 I95Y81-L90 HydrophobicContact CD2-CD1 3.85Å; Y81-L90 HydrophobicContact CD2-CD2 4.31Å; Y81-L90 HydrophobicContact CE1-CD2 4.4Å; Y81-L90 HydrophobicContact CE2-CD1 3.74Å; Y81-L90 HydrophobicContact CE2-CD2 3.54Å; Y81-L90 HydrophobicContact CE2-CG 4.29Å; L84-L90 HydrophobicContact CB-CB 4.05Å; L84-L90 HydrophobicContact CB-CD1 4.06Å; L84-L90 HydrophobicContact CD1-CD1 4.45Å; L84-L90 WeakPolarHBondContact O-CB 3.42Å; L84-L90 PolarHBondContact O-N 2.85Å; V85-L90 HydrophobicContact CG2-CD2 3.63Å; G88-L90 VanDerWaalsContact C-N 3.32Å; G88-L90 PolarHBondContact O-N 3.45Å; L90-N92 PolarHBondContact O-N 3.47Å; L90-T93 PolarHBondContact O-N 3.18Å; L90-I95 HydrophobicContact CD1-CD1 3.85Å
91E93.9Very high96.1Very high128 Ų12871.9 Ų71.960%0.59838%0.378SS*.G310 helixtrans-73.3-17.3-179.1-60.1-48.5115.500113E89 R129 P131E89-E91 PolarHBondContact O-N 2.75Å; E91-R129 IonicContact OE1-CZ 3.6Å; E91-R129 IonicContact OE1-NH2 3.25Å; E91-R129 PolarHBondContact OE1-NH2 3.26Å; E91-R129 IonicContact OE2-NH2 3.83Å; E91-P131 WeakPolarHBondContact O-CG 3.46Å
92N95.1Very high96Very high116 Ų11667.9 Ų67.962%0.6237%0.366SS*.G310 helixtrans-90.8-10175-168.633.1000112.2E89 L90E89-N92 WeakPolarHBondContact O-CB 3.38Å; E89-N92 PolarHBondContact O-N 3.26Å; E89-N92 VanDerWaalsContact O-N 3.11Å; E89-N92 WeakPolarHBondContact OE2-CB 3.37Å; E89-N92 PolarHBondContact OE2-ND2 2.93Å; L90-N92 PolarHBondContact O-N 3.47Å
93T96.1Very high95.8Very high38 Ų3867.1 Ų67.123%0.23336%0.358CS..  trans-108.1122.3-168.7-63.10000112.6L84 E89 L90 I95L84-T93 HydrophobicContact CD1-CG2 3.93Å; L84-T93 HydrophobicContact CD2-CG2 4.33Å; E89-T93 WeakPolarHBondContact O-CB 3.48Å; E89-T93 PolarHBondContact O-N 2.98Å; E89-T93 VanDerWaalsContact O-N 3.1Å; E89-T93 PolarHBondContact O-OG1 3.01Å; L90-T93 PolarHBondContact O-N 3.18Å; T93-I95 HydrophobicContact CG2-CG1 4.04Å
94Y95.8Very high95.7Very high67 Ų6763.4 Ų63.426%0.26334%0.34SS..  trans-77.1122162.7-73-87.7000110.9I128 R129 P131 V133 I155 L170Y94-I128 HydrophobicContact CD1-CD1 4.29Å; Y94-R129 CarbonylContact C-O 3.57Å; Y94-R129 VanDerWaalsContact CA-O 3.28Å; Y94-R129 WeakPolarHBondContact CA-O 3.25Å; Y94-P131 HydrophobicContact CD2-CG 4.31Å; Y94-P131 WeakPolarHBondContact CE1-O 3.43Å; Y94-P131 HydrophobicContact CE2-CB 4.21Å; Y94-P131 HydrophobicContact CE2-CG 3.79Å; Y94-P131 PolarHBondContact OH-O 3.16Å; Y94-P131 VanDerWaalsContact OH-O 3.08Å; Y94-V133 HydrophobicContact CE1-CG2 4.07Å; Y94-I155 HydrophobicContact CD1-CD1 4.02Å; Y94-I155 HydrophobicContact CD2-CB 4.48Å; Y94-I155 HydrophobicContact CD2-CD1 4.04Å; Y94-I155 HydrophobicContact CD2-CG1 4.12Å; Y94-I155 HydrophobicContact CD2-CG2 3.52Å; Y94-I155 HydrophobicContact CE1-CD1 4.41Å; Y94-I155 HydrophobicContact CE1-CG1 4.49Å; Y94-I155 HydrophobicContact CE2-CB 4.48Å; Y94-I155 HydrophobicContact CE2-CD1 4.43Å; Y94-I155 HydrophobicContact CE2-CG1 4.07Å; Y94-I155 HydrophobicContact CE2-CG2 3.74Å; Y94-I155 HydrophobicContact CG-CD1 3.8Å; Y94-I155 HydrophobicContact CG-CG1 4.34Å; Y94-I155 HydrophobicContact CG-CG2 4.32Å; Y94-L170 HydrophobicContact CE1-CD2 4.29Å
95I96.3Very high95.6Very high40 Ų4062.9 Ų62.921%0.20534%0.337CS..EExtended strand (participates in β ladder)trans-108.4120.9173.2-53.9178.1000107.6Y81 L84 L90 T93 I128 R129Y81-I95 HydrophobicContact CD2-CD1 4.33Å; L84-I95 HydrophobicContact CD1-CD1 3.81Å; L84-I95 HydrophobicContact CD1-CG1 4.26Å; L90-I95 HydrophobicContact CD1-CD1 3.85Å; T93-I95 HydrophobicContact CG2-CG1 4.04Å; I95-I128 CarbonylContact O-C 3.59Å; I95-I128 WeakPolarHBondContact O-CA 3.47Å; I95-R129 HydrophobicContact CB-CB 4.45Å; I95-R129 PolarHBondContact N-O 2.8Å; I95-R129 PolarHBondContact O-N 3.12Å
96I96.3Very high95.5Very high49 Ų4959.2 Ų59.225%0.25132%0.315SS..EExtended strand (participates in β ladder)trans-119.5123.7176.7-52.5177.4000108.1F126 F127 I128 L148I96-F126 HydrophobicContact CG2-CE2 4.15Å; I96-F126 HydrophobicContact CG2-CZ 4.05Å; I96-F127 WeakPolarHBondContact CA-O 3.32Å; I96-I128 HydrophobicContact CD1-CD1 4.13Å; I96-I128 HydrophobicContact CG1-CD1 3.9Å; I96-I128 HydrophobicContact CG1-CG1 4.01Å; I96-L148 HydrophobicContact CG2-CD2 3.81Å
97Y96.3Very high95.4Very high89 Ų8952 Ų5235%0.34928%0.281SS..EExtended strand (participates in β ladder)trans-114.1129175.2-177.3-80.4000109.6V73 V77 P125 F126 F127V73-Y97 HydrophobicContact CG1-CE2 4.41Å; V77-Y97 HydrophobicContact CG2-CD2 4.22Å; V77-Y97 HydrophobicContact CG2-CE2 4.15Å; Y97-P125 HydrophobicContact CE1-CG 4.3Å; Y97-F126 WeakPolarHBondContact O-CA 3.34Å; Y97-F127 AromaticContact CD1-CD2 3.92Å; Y97-F127 HydrophobicContact CD1-CD2 3.92Å; Y97-F127 HydrophobicContact CD1-CE2 4.5Å; Y97-F127 PolarHBondContact N-O 2.91Å; Y97-F127 PolarHBondContact O-N 3.48Å
98T96.2Very high95.4Very high47 Ų4748.1 Ų48.129%0.28826%0.257SS..EExtended strand (participates in β ladder)trans-157.5166.6-178.7-172.10000111.1P125 L148T98-P125 WeakPolarHBondContact CA-O 3.41Å; T98-P125 PolarHBondContact OG1-O 2.81Å; T98-L148 HydrophobicContact CG2-CD1 4.03Å; T98-L148 HydrophobicContact CG2-CD2 4.45Å
99A95.1Very high95.2Very high33 Ų3345.5 Ų45.527%0.27323%0.231SC..  trans-112.1162.7169.100000111.8V124 P125 N145A99-V124 HydrophobicContact CB-CB 4.08Å; A99-V124 HydrophobicContact CB-CG1 3.91Å; A99-P125 HydrophobicContact CB-CG 4.41Å; A99-N145 PolarHBondContact O-ND2 3.44Å
100D92.9Very high95.1Very high114 Ų11441.2 Ų41.261%0.6121%0.21SC*.SBendtrans-81.4-26.4178.564.1-36.6000113.5N145D100-N145 PolarHBondContact O-ND2 3.08Å
101H94.4Very high95Very high53 Ų5341 Ų4125%0.24521%0.209CC..SBendtrans-161.4168.2177.55556.9000111.9K114H101-K114 VanDerWaalsContact CD2-CD 3.44Å; H101-K114 WeakPolarHBondContact CD2-CD 3.4Å; H101-K114 PolarHBondContact CD2-NZ 2.04Å; H101-K114 WeakPolarHBondContact CE1-CD 3.44Å; H101-K114 WeakPolarHBondContact NE2-CD 3.43Å; H101-K114 WeakPolarHBondContact NE2-CE 3.38Å; H101-K114 PolarHBondContact NE2-NZ 2.63Å
102G94.2Very high95Very high9 Ų936 Ų369%0.09319%0.186CC..  trans-74-171.5165.700000113F120 D121G102-F120 CarbonylContact C-O 3.6Å; G102-F120 VanDerWaalsContact CA-O 3.27Å; G102-F120 WeakPolarHBondContact CA-O 3.16Å; G102-D121 WeakPolarHBondContact CA-O 3.41Å; G102-D121 PolarHBondContact N-O 3.01Å
103Y94.3Very high94.8Very high46 Ų4631 Ų3118%0.1816%0.162CC..  trans-160.2119.5-178.6-163.7-94.5000113.4R66 I105 K112 G113 K114 F120R66-Y103 VanDerWaalsContact NH2-CD1 3.34Å; R66-Y103 VanDerWaalsContact NH2-CG 3.3Å; Y103-I105 HydrophobicContact CD1-CD1 4.06Å; Y103-I105 HydrophobicContact CD1-CG1 3.64Å; Y103-I105 HydrophobicContact CE1-CD1 4.2Å; Y103-I105 HydrophobicContact CE1-CG1 3.75Å; Y103-K112 HydrophobicContact CE1-CB 4.17Å; Y103-K112 WeakPolarHBondContact OH-CD 3.14Å; Y103-G113 WeakPolarHBondContact CA-O 3.28Å; Y103-G113 WeakPolarHBondContact CD2-O 3.19Å; Y103-K114 HydrophobicContact CD2-CB 4.3Å; Y103-F120 PolarHBondContact N-O 3.26Å
104H94.8Very high94.6Very high0 Ų033 Ų330%017%0.168CC..BIsolated β-bridgetrans-84.8144.417357-98.1000114.3Q107 L110 K112 G113 K114 F120 D121H104-Q107 HydrophobicContact CB-CB 4.33Å; H104-L110 WeakPolarHBondContact CD2-CB 3.26Å; H104-K112 WeakPolarHBondContact O-CA 3.32Å; H104-G113 PolarHBondContact CD2-N 3.11Å; H104-G113 VanDerWaalsContact CD2-N 3.27Å; H104-G113 VanDerWaalsContact CE1-CA 3.46Å; H104-G113 WeakPolarHBondContact CE1-CA 3.38Å; H104-G113 PolarHBondContact N-O 3.04Å; H104-G113 VanDerWaalsContact N-O 3.09Å; H104-G113 PolarHBondContact ND1-O 2.75Å; H104-G113 WeakPolarHBondContact NE2-CA 3.29Å; H104-G113 PolarHBondContact NE2-N 2.89Å; H104-G113 PolarHBondContact O-N 3.36Å; H104-G113 VanDerWaalsContact O-N 3.17Å; H104-K114 PolarHBondContact CE1-N 2.86Å; H104-F120 HydrophobicContact CB-CD2 3.68Å; H104-F120 HydrophobicContact CB-CE2 3.57Å; H104-F120 HydrophobicContact CB-CZ 4.45Å; H104-F120 AromaticContact ND1-CE2 4Å; H104-D121 IonicContact CE1-OD1 3.42Å; H104-D121 IonicContact CE1-OD2 2.7Å; H104-D121 PolarHBondContact CE1-OD2 2.92Å; H104-D121 IonicContact CG-OD1 2.7Å; H104-D121 PolarHBondContact N-OD1 3.03Å; H104-D121 VanDerWaalsContact N-OD1 3.15Å; H104-D121 IonicContact ND1-OD1 2.94Å; H104-D121 PolarHBondContact ND1-OD1 3.14Å; H104-D121 IonicContact ND1-OD2 3.5Å; H104-D121 PolarHBondContact ND1-OD2 2.79Å
105I95.3Very high94.3Very high7 Ų730.8 Ų30.84%0.03616%0.162CC..SBendtrans-139.890.6176.8-55.9179.1000106.7H28 Y33 T59 L62 Q63 Y103 Q107H28-I105 HydrophobicContact CB-CB 4.26Å; H28-I105 HydrophobicContact CB-CG2 4.35Å; Y33-I105 WeakPolarHBondContact CD2-O 3.49Å; T59-I105 HydrophobicContact CG2-CG2 3.63Å; L62-I105 HydrophobicContact CD2-CG1 4.43Å; L62-I105 HydrophobicContact CD2-CG2 4.29Å; Q63-I105 HydrophobicContact CB-CD1 4.25Å; Y103-I105 HydrophobicContact CD1-CD1 4.06Å; Y103-I105 HydrophobicContact CD1-CG1 3.64Å; Y103-I105 HydrophobicContact CE1-CD1 4.2Å; Y103-I105 HydrophobicContact CE1-CG1 3.75Å; I105-Q107 VanDerWaalsContact C-OE1 3.27Å; I105-Q107 PolarHBondContact O-N 3.38Å; I105-Q107 PolarHBondContact O-NE2 2.9Å; I105-Q107 PolarHBondContact O-OE1 3.11Å; I105-Q107 VanDerWaalsContact O-OE1 3.1Å
106G95.4Very high94.2Very high0 Ų029 Ų290%015%0.152CC..SBendtrans83.1-9.2177.800000116.8N34 F108 G109 L110 V111N34-G106 PolarHBondContact N-O 2.77Å; G106-F108 PolarHBondContact O-N 3.26Å; G106-G109 PolarHBondContact O-N 3.46Å; G106-G109 VanDerWaalsContact O-N 3.17Å; G106-L110 VanDerWaalsContact CA-O 3.27Å; G106-L110 WeakPolarHBondContact CA-O 3.47Å; G106-L110 PolarHBondContact N-O 2.63Å; G106-V111 PolarHBondContact N-O 3.41Å
107Q96.3Very high94.1Very high12 Ų1226.6 Ų26.66%0.05614%0.14CC..BIsolated β-bridgetrans-58.6134.7175-73.169.633.900111.4H28 T30 S32 H104 I105 G109 L110 F120H28-Q107 PolarHBondContact O-NE2 2.85Å; T30-Q107 PolarHBondContact OG1-NE2 3.21Å; S32-Q107 CarbonylContact O-C 3.57Å; S32-Q107 WeakPolarHBondContact O-CA 3.47Å; H104-Q107 HydrophobicContact CB-CB 4.33Å; I105-Q107 VanDerWaalsContact C-OE1 3.27Å; I105-Q107 PolarHBondContact O-N 3.38Å; I105-Q107 PolarHBondContact O-NE2 2.9Å; I105-Q107 PolarHBondContact O-OE1 3.11Å; I105-Q107 VanDerWaalsContact O-OE1 3.1Å; Q107-G109 PolarHBondContact O-N 2.83Å; Q107-G109 VanDerWaalsContact O-N 3.1Å; Q107-L110 VanDerWaalsContact O-CB 3.25Å; Q107-L110 WeakPolarHBondContact O-CB 3.49Å; Q107-L110 WeakPolarHBondContact O-CG 3.26Å; Q107-L110 PolarHBondContact O-N 3.17Å; Q107-F120 HydrophobicContact CB-CD1 4.22Å; Q107-F120 HydrophobicContact CB-CE1 3.64Å; Q107-F120 HydrophobicContact CB-CE2 4.22Å; Q107-F120 HydrophobicContact CB-CZ 3.62Å; Q107-F120 HydrophobicContact CG-CD1 3.94Å; Q107-F120 HydrophobicContact CG-CE1 3.85Å; Q107-F120 HydrophobicContact CG-CG 4.42Å; Q107-F120 HydrophobicContact CG-CZ 4.26Å
108F95.6Very high94Very high0 Ų022.4 Ų22.40%012%0.124CC..THydrogen-bonded Turntrans50.230.4-175-53.5-53.2000114.8S32 Y35 K41 M45 T48 G106 L110 Y118 F120 Y592 Q593 L594S32-F108 PolarHBondContact O-N 3.04Å; Y35-F108 HydrophobicContact CD1-CD1 4.12Å; Y35-F108 HydrophobicContact CD1-CE1 4.17Å; Y35-F108 WeakPolarHBondContact O-CA 3.32Å; K41-F108 HydrophobicContact CD-CE1 4.48Å; K41-F108 HydrophobicContact CD-CZ 4.5Å; M45-F108 HydrophobicContact SD-CB 3.84Å; M45-F108 HydrophobicContact SD-CD2 4.28Å; M45-F108 HydrophobicContact SD-CG 4.37Å; T48-F108 VanDerWaalsContact CG2-O 3.23Å; T48-F108 WeakPolarHBondContact CG2-O 3.33Å; G106-F108 PolarHBondContact O-N 3.26Å; F108-L110 VanDerWaalsContact C-N 3.27Å; F108-L110 PolarHBondContact O-N 3.47Å; F108-Y118 AromaticContact CD2-CD2 3.78Å; F108-Y118 HydrophobicContact CD2-CD2 3.78Å; F108-Y118 AromaticContact CD2-CE2 3.64Å; F108-Y118 HydrophobicContact CD2-CE2 3.64Å; F108-Y118 HydrophobicContact CD2-CG 4.5Å; F108-Y118 HydrophobicContact CE2-CD1 4.24Å; F108-Y118 AromaticContact CE2-CD2 3.68Å; F108-Y118 HydrophobicContact CE2-CD2 3.68Å; F108-Y118 HydrophobicContact CE2-CE1 4.34Å; F108-Y118 AromaticContact CE2-CE2 3.75Å; F108-Y118 HydrophobicContact CE2-CE2 3.75Å; F108-Y118 AromaticContact CE2-CG 3.94Å; F108-Y118 HydrophobicContact CE2-CG 3.94Å; F108-F120 HydrophobicContact CD2-CE1 4.06Å; F108-F120 AromaticContact CD2-CZ 3.83Å; F108-F120 HydrophobicContact CD2-CZ 3.83Å; F108-F120 AromaticContact CE2-CE1 3.68Å; F108-F120 HydrophobicContact CE2-CE1 3.68Å; F108-F120 AromaticContact CE2-CZ 3.87Å; F108-F120 HydrophobicContact CE2-CZ 3.87Å; F108-Y592 WeakPolarHBondContact CZ-O 3.38Å; F108-Q593 HydrophobicContact CZ-CB 4.17Å; F108-Q593 VanDerWaalsContact CZ-O 3.3Å; F108-Q593 WeakPolarHBondContact CZ-O 3.44Å; F108-L594 HydrophobicContact CE1-CD2 4.3Å
109G94.2Very high93.9Very high6 Ų621.1 Ų21.16%0.06212%0.115CC..THydrogen-bonded Turntrans79.81.1-177.800000114.9G106 Q107 V111G106-G109 PolarHBondContact O-N 3.46Å; G106-G109 VanDerWaalsContact O-N 3.17Å; Q107-G109 PolarHBondContact O-N 2.83Å; Q107-G109 VanDerWaalsContact O-N 3.1Å; G109-V111 PolarHBondContact O-N 2.86Å
110L94.1Very high93.9Very high1 Ų121.7 Ų21.71%0.00511%0.111CC..  trans-80.8102.5-177.3-57.7166.9000111M45 T48 H104 G106 Q107 F108 K112 M116 T553M45-L110 HydrophobicContact CE-CD1 3.88Å; M45-L110 HydrophobicContact CE-CD2 3.81Å; M45-L110 HydrophobicContact CE-CG 4.19Å; M45-L110 HydrophobicContact SD-CD1 4.1Å; T48-L110 HydrophobicContact CG2-CD2 4.25Å; H104-L110 WeakPolarHBondContact CD2-CB 3.26Å; G106-L110 VanDerWaalsContact CA-O 3.27Å; G106-L110 WeakPolarHBondContact CA-O 3.47Å; G106-L110 PolarHBondContact N-O 2.63Å; Q107-L110 VanDerWaalsContact O-CB 3.25Å; Q107-L110 WeakPolarHBondContact O-CB 3.49Å; Q107-L110 WeakPolarHBondContact O-CG 3.26Å; Q107-L110 PolarHBondContact O-N 3.17Å; F108-L110 VanDerWaalsContact C-N 3.27Å; F108-L110 PolarHBondContact O-N 3.47Å; L110-K112 PolarHBondContact O-N 3.05Å; L110-M116 HydrophobicContact CD1-CE 3.82Å; L110-M116 HydrophobicContact CD1-CG 3.71Å; L110-M116 HydrophobicContact CD1-SD 4.4Å; L110-M116 HydrophobicContact CD2-CE 4.01Å; L110-T553 HydrophobicContact CB-CG2 4.19Å; L110-T553 HydrophobicContact CD2-CG2 4.36Å
111V93.7Very high94Very high5 Ų516.6 Ų16.63%0.038%0.084CC..  trans-47.8-55.7-175.1-170.70000113.3M51 H55 F58 T59 G106 G109 F549 A551 T553M51-V111 HydrophobicContact SD-CG2 4.48Å; H55-V111 HydrophobicContact CB-CG2 3.98Å; F58-V111 HydrophobicContact CD1-CG1 3.65Å; F58-V111 HydrophobicContact CE1-CG1 4.12Å; T59-V111 HydrophobicContact CG2-CG1 4.13Å; T59-V111 WeakPolarHBondContact CG2-O 3.48Å; G106-V111 PolarHBondContact N-O 3.41Å; G109-V111 PolarHBondContact O-N 2.86Å; V111-F549 HydrophobicContact CG1-CE2 4.11Å; V111-F549 HydrophobicContact CG1-CZ 4.37Å; V111-A551 HydrophobicContact CB-CB 3.98Å; V111-A551 HydrophobicContact CG1-CB 4.5Å; V111-A551 HydrophobicContact CG2-CB 4.03Å; V111-T553 HydrophobicContact CB-CG2 4.45Å
112K92.5Very high94Very high24 Ų2416.1 Ų16.110%0.1048%0.083CC..SBendtrans-155.4150.2167.577.5-174.4-170.6176.10113.9E12 F58 L62 Y103 H104 L110 H537 T553E12-K112 VanDerWaalsContact CD-NZ 3.34Å; E12-K112 IonicContact OE1-NZ 3.98Å; E12-K112 PolarHBondContact OE1-NZ 2.63Å; E12-K112 IonicContact OE2-NZ 3.02Å; E12-K112 PolarHBondContact OE2-NZ 3Å; F58-K112 HydrophobicContact CE1-CD 4.13Å; L62-K112 HydrophobicContact CD1-CD 4.21Å; L62-K112 HydrophobicContact CD2-CB 3.65Å; L62-K112 HydrophobicContact CD2-CD 3.46Å; L62-K112 VanDerWaalsContact CD2-CD 3.46Å; L62-K112 HydrophobicContact CD2-CG 4.22Å; Y103-K112 HydrophobicContact CE1-CB 4.17Å; Y103-K112 WeakPolarHBondContact OH-CD 3.14Å; H104-K112 WeakPolarHBondContact O-CA 3.32Å; L110-K112 PolarHBondContact O-N 3.05Å; K112-H537 PolarHBondContact NZ-CE1 2.8Å; K112-H537 VanDerWaalsContact NZ-CE1 3.31Å; K112-H537 PolarHBondContact NZ-NE2 2.84Å; K112-T553 WeakPolarHBondContact O-CB 3.17Å; K112-T553 WeakPolarHBondContact O-CG2 3.39Å; K112-T553 PolarHBondContact O-OG1 3.48Å
113G91.9Very high94Very high12 Ų1224.1 Ų24.112%0.12411%0.11CC..BIsolated β-bridgetrans169-166.7176.700000115.8Y103 H104Y103-G113 WeakPolarHBondContact CA-O 3.28Å; Y103-G113 WeakPolarHBondContact CD2-O 3.19Å; H104-G113 PolarHBondContact CD2-N 3.11Å; H104-G113 VanDerWaalsContact CD2-N 3.27Å; H104-G113 VanDerWaalsContact CE1-CA 3.46Å; H104-G113 WeakPolarHBondContact CE1-CA 3.38Å; H104-G113 PolarHBondContact N-O 3.04Å; H104-G113 VanDerWaalsContact N-O 3.09Å; H104-G113 PolarHBondContact ND1-O 2.75Å; H104-G113 WeakPolarHBondContact NE2-CA 3.29Å; H104-G113 PolarHBondContact NE2-N 2.89Å; H104-G113 PolarHBondContact O-N 3.36Å; H104-G113 VanDerWaalsContact O-N 3.17Å
114K91.5Very high94.1Very high80 Ų8023.7 Ų23.735%0.34811%0.113SC..SBendtrans-165.364.2-173.349.3166.8-177.9175.90110.2H101 Y103 H104H101-K114 VanDerWaalsContact CD2-CD 3.44Å; H101-K114 WeakPolarHBondContact CD2-CD 3.4Å; H101-K114 PolarHBondContact CD2-NZ 2.04Å; H101-K114 WeakPolarHBondContact CE1-CD 3.44Å; H101-K114 WeakPolarHBondContact NE2-CD 3.43Å; H101-K114 WeakPolarHBondContact NE2-CE 3.38Å; H101-K114 PolarHBondContact NE2-NZ 2.63Å; Y103-K114 HydrophobicContact CD2-CB 4.3Å; H104-K114 PolarHBondContact CE1-N 2.86Å
115S89.8Confident94.1Very high19 Ų1926.6 Ų26.613%0.13313%0.131CC..  trans-155.39.4-162.4-81.50000116.9D121 R199S115-D121 PolarHBondContact N-OD2 2.74Å; S115-R199 VanDerWaalsContact CA-NH1 3.28Å; S115-R199 PolarHBondContact O-NH1 3Å; S115-R199 PolarHBondContact OG-NH1 2.73Å; S115-R199 PolarHBondContact OG-NH2 2.96Å
116M92.8Very high94.1Very high2 Ų228.7 Ų28.71%0.0114%0.141CC..SBendtrans-110.3163.4177.6-55.4-52.5160.300110.7I44 M45 L110 Y118 D121 T553 Y560I44-M116 HydrophobicContact CD1-CE 4.28Å; I44-M116 HydrophobicContact CG2-CE 4.14Å; M45-M116 HydrophobicContact CE-CE 3.76Å; M45-M116 HydrophobicContact CE-SD 3.77Å; L110-M116 HydrophobicContact CD1-CE 3.82Å; L110-M116 HydrophobicContact CD1-CG 3.71Å; L110-M116 HydrophobicContact CD1-SD 4.4Å; L110-M116 HydrophobicContact CD2-CE 4.01Å; M116-Y118 VanDerWaalsContact C-N 3.28Å; M116-Y118 HydrophobicContact CB-CD2 3.42Å; M116-Y118 VanDerWaalsContact CB-CD2 3.42Å; M116-Y118 HydrophobicContact CB-CE2 3.83Å; M116-Y118 HydrophobicContact CB-CG 4.26Å; M116-Y118 HydrophobicContact CG-CD2 4.09Å; M116-Y118 HydrophobicContact CG-CE2 4.2Å; M116-Y118 PolarHBondContact O-N 3.02Å; M116-D121 WeakPolarHBondContact CB-OD2 3.4Å; M116-D121 PolarHBondContact N-OD2 3.13Å; M116-D121 WeakPolarHBondContact O-CB 3.1Å; M116-T553 WeakPolarHBondContact CE-O 3.34Å; M116-Y560 PolarHBondContact O-OH 3.45Å
117P94.1Very high94.1Very high0 Ų035.3 Ų35.30%017%0.17CC..SBendtrans-79.9-6.4177.832.1-36.4000114.6Y560 C562 L573 C575 F577P117-Y560 HydrophobicContact CB-CD2 4.08Å; P117-Y560 HydrophobicContact CB-CE2 3.72Å; P117-C562 WeakPolarHBondContact CB-SG 3.43Å; P117-L573 WeakPolarHBondContact O-CD2 3.43Å; P117-C575 VanDerWaalsContact CB-SG 3.51Å; P117-F577 HydrophobicContact CG-CZ 4.13Å
118Y95.7Very high94.1Very high0 Ų036.3 Ų36.30%018%0.175CC..SBendtrans-66.6155-171.4-56.3-48000113.5H42 M45 F108 M116 F120 D121 I122 E583 F585 Q593H42-Y118 AromaticContact CE1-CZ 3.91Å; H42-Y118 PolarHBondContact CE1-OH 2.7Å; H42-Y118 VanDerWaalsContact CE1-OH 3.23Å; H42-Y118 PolarHBondContact ND1-OH 3.32Å; H42-Y118 VanDerWaalsContact ND1-OH 3.11Å; M45-Y118 HydrophobicContact CG-CE2 4.39Å; M45-Y118 WeakPolarHBondContact CG-OH 3.35Å; M45-Y118 HydrophobicContact SD-CE2 3.8Å; F108-Y118 AromaticContact CD2-CD2 3.78Å; F108-Y118 HydrophobicContact CD2-CD2 3.78Å; F108-Y118 AromaticContact CD2-CE2 3.64Å; F108-Y118 HydrophobicContact CD2-CE2 3.64Å; F108-Y118 HydrophobicContact CD2-CG 4.5Å; F108-Y118 HydrophobicContact CE2-CD1 4.24Å; F108-Y118 AromaticContact CE2-CD2 3.68Å; F108-Y118 HydrophobicContact CE2-CD2 3.68Å; F108-Y118 HydrophobicContact CE2-CE1 4.34Å; F108-Y118 AromaticContact CE2-CE2 3.75Å; F108-Y118 HydrophobicContact CE2-CE2 3.75Å; F108-Y118 AromaticContact CE2-CG 3.94Å; F108-Y118 HydrophobicContact CE2-CG 3.94Å; M116-Y118 VanDerWaalsContact C-N 3.28Å; M116-Y118 HydrophobicContact CB-CD2 3.42Å; M116-Y118 VanDerWaalsContact CB-CD2 3.42Å; M116-Y118 HydrophobicContact CB-CE2 3.83Å; M116-Y118 HydrophobicContact CB-CG 4.26Å; M116-Y118 HydrophobicContact CG-CD2 4.09Å; M116-Y118 HydrophobicContact CG-CE2 4.2Å; M116-Y118 PolarHBondContact O-N 3.02Å; Y118-F120 VanDerWaalsContact CB-CZ 3.47Å; Y118-F120 HydrophobicContact CD2-CE1 4.11Å; Y118-F120 HydrophobicContact CD2-CE2 4.02Å; Y118-F120 AromaticContact CD2-CZ 3.43Å; Y118-F120 HydrophobicContact CD2-CZ 3.43Å; Y118-F120 VanDerWaalsContact CD2-CZ 3.43Å; Y118-F120 HydrophobicContact CG-CE1 4.07Å; Y118-F120 HydrophobicContact CG-CE2 4.39Å; Y118-F120 AromaticContact CG-CZ 3.81Å; Y118-F120 HydrophobicContact CG-CZ 3.81Å; Y118-F120 PolarHBondContact O-N 3.29Å; Y118-F120 VanDerWaalsContact O-N 3.12Å; Y118-D121 PolarHBondContact O-N 3.01Å; Y118-I122 PolarHBondContact O-N 3.32Å; Y118-E583 PolarHBondContact OH-OE1 3.17Å; Y118-E583 VanDerWaalsContact OH-OE1 3.12Å; Y118-E583 PolarHBondContact OH-OE2 2.97Å; Y118-F585 HydrophobicContact CD1-CE2 4.32Å; Y118-F585 AromaticContact CE1-CE2 3.81Å; Y118-F585 HydrophobicContact CE1-CE2 3.81Å; Y118-F585 HydrophobicContact CE1-CZ 4.01Å; Y118-Q593 VanDerWaalsContact CB-OE1 3.24Å; Y118-Q593 HydrophobicContact CD1-CB 4.38Å
119D94.1Very high94Very high20 Ų2040.5 Ų40.511%0.10719%0.191CC..Hα-helixtrans-57.6-36.8-169.7-15078.5000110.8D121 I122 R123 R564 M587D119-D121 VanDerWaalsContact C-N 3.28Å; D119-D121 PolarHBondContact O-N 3.34Å; D119-I122 PolarHBondContact O-N 3.02Å; D119-R123 WeakPolarHBondContact O-CB 3.4Å; D119-R123 PolarHBondContact O-N 2.86Å; D119-R123 WeakPolarHBondContact OD2-CD 3.4Å; D119-R123 IonicContact OD2-CZ 3.09Å; D119-R123 IonicContact OD2-NE 2.67Å; D119-R123 IonicContact OD2-NH1 3.98Å; D119-R123 PolarHBondContact OD2-NH1 3.44Å; D119-R123 VanDerWaalsContact OD2-NH1 3.11Å; D119-R564 IonicContact OD1-CZ 2.73Å; D119-R564 IonicContact OD1-NE 3.42Å; D119-R564 PolarHBondContact OD1-NE 3.26Å; D119-R564 IonicContact OD1-NH2 2.96Å; D119-R564 PolarHBondContact OD1-NH2 2.92Å; D119-M587 HydrophobicContact CB-CE 3.69Å
120F94.1Very high93.9Very high45 Ų4540.9 Ų40.920%0.19720%0.195CC..Hα-helixtrans-64.8-19.7177.156.2-113.6000115.7G102 Y103 H104 Q107 F108 Y118G102-F120 CarbonylContact C-O 3.6Å; G102-F120 VanDerWaalsContact CA-O 3.27Å; G102-F120 WeakPolarHBondContact CA-O 3.16Å; Y103-F120 PolarHBondContact N-O 3.26Å; H104-F120 HydrophobicContact CB-CD2 3.68Å; H104-F120 HydrophobicContact CB-CE2 3.57Å; H104-F120 HydrophobicContact CB-CZ 4.45Å; H104-F120 AromaticContact ND1-CE2 4Å; Q107-F120 HydrophobicContact CB-CD1 4.22Å; Q107-F120 HydrophobicContact CB-CE1 3.64Å; Q107-F120 HydrophobicContact CB-CE2 4.22Å; Q107-F120 HydrophobicContact CB-CZ 3.62Å; Q107-F120 HydrophobicContact CG-CD1 3.94Å; Q107-F120 HydrophobicContact CG-CE1 3.85Å; Q107-F120 HydrophobicContact CG-CG 4.42Å; Q107-F120 HydrophobicContact CG-CZ 4.26Å; F108-F120 HydrophobicContact CD2-CE1 4.06Å; F108-F120 AromaticContact CD2-CZ 3.83Å; F108-F120 HydrophobicContact CD2-CZ 3.83Å; F108-F120 AromaticContact CE2-CE1 3.68Å; F108-F120 HydrophobicContact CE2-CE1 3.68Å; F108-F120 AromaticContact CE2-CZ 3.87Å; F108-F120 HydrophobicContact CE2-CZ 3.87Å; Y118-F120 VanDerWaalsContact CB-CZ 3.47Å; Y118-F120 HydrophobicContact CD2-CE1 4.11Å; Y118-F120 HydrophobicContact CD2-CE2 4.02Å; Y118-F120 AromaticContact CD2-CZ 3.43Å; Y118-F120 HydrophobicContact CD2-CZ 3.43Å; Y118-F120 VanDerWaalsContact CD2-CZ 3.43Å; Y118-F120 HydrophobicContact CG-CE1 4.07Å; Y118-F120 HydrophobicContact CG-CE2 4.39Å; Y118-F120 AromaticContact CG-CZ 3.81Å; Y118-F120 HydrophobicContact CG-CZ 3.81Å; Y118-F120 PolarHBondContact O-N 3.29Å; Y118-F120 VanDerWaalsContact O-N 3.12Å
121D94.9Very high93.8Very high7 Ų743 Ų434%0.03721%0.208CC..Hα-helixtrans-100.3-18.5178.5-95.86.2000112.6G102 H104 S115 M116 Y118 D119G102-D121 WeakPolarHBondContact CA-O 3.41Å; G102-D121 PolarHBondContact N-O 3.01Å; H104-D121 IonicContact CE1-OD1 3.42Å; H104-D121 IonicContact CE1-OD2 2.7Å; H104-D121 PolarHBondContact CE1-OD2 2.92Å; H104-D121 IonicContact CG-OD1 2.7Å; H104-D121 PolarHBondContact N-OD1 3.03Å; H104-D121 VanDerWaalsContact N-OD1 3.15Å; H104-D121 IonicContact ND1-OD1 2.94Å; H104-D121 PolarHBondContact ND1-OD1 3.14Å; H104-D121 IonicContact ND1-OD2 3.5Å; H104-D121 PolarHBondContact ND1-OD2 2.79Å; S115-D121 PolarHBondContact N-OD2 2.74Å; M116-D121 WeakPolarHBondContact CB-OD2 3.4Å; M116-D121 PolarHBondContact N-OD2 3.13Å; M116-D121 WeakPolarHBondContact O-CB 3.1Å; Y118-D121 PolarHBondContact O-N 3.01Å; D119-D121 VanDerWaalsContact C-N 3.28Å; D119-D121 PolarHBondContact O-N 3.34Å
122I94.8Very high93.4Very high44 Ų4447.3 Ų47.323%0.22624%0.239CC..Hα-helixtrans-109.3-25.4-175.866.3173000113.9Y118 D119 V197 R564Y118-I122 PolarHBondContact O-N 3.32Å; D119-I122 PolarHBondContact O-N 3.02Å; I122-V197 HydrophobicContact CD1-CG2 3.95Å; I122-V197 HydrophobicContact CG2-CG1 3.86Å; I122-V197 HydrophobicContact CG2-CG2 4.45Å; I122-R564 HydrophobicContact CD1-CG 4.47Å
123R94.7Very high93.3Very high176 Ų17647.3 Ų47.366%0.66424%0.241SC*.  trans-86.3131.1-176.2-172.5169.2175.1179.7-1.1110.8D119D119-R123 WeakPolarHBondContact O-CB 3.4Å; D119-R123 PolarHBondContact O-N 2.86Å; D119-R123 WeakPolarHBondContact OD2-CD 3.4Å; D119-R123 IonicContact OD2-CZ 3.09Å; D119-R123 IonicContact OD2-NE 2.67Å; D119-R123 IonicContact OD2-NH1 3.98Å; D119-R123 PolarHBondContact OD2-NH1 3.44Å; D119-R123 VanDerWaalsContact OD2-NH1 3.11Å
124V95.5Very high93.2Very high38 Ų3852.1 Ų52.123%0.2326%0.26CS..  trans-125153.5-177.2-66.60000110.6A99A99-V124 HydrophobicContact CB-CB 4.08Å; A99-V124 HydrophobicContact CB-CG1 3.91Å
125P95Very high93.2Very high60 Ų6053.9 Ų53.939%0.3928%0.28SS..  trans-64.2145.8163.329.8-34.8000109.7Y97 T98 A99 F127Y97-P125 HydrophobicContact CE1-CG 4.3Å; T98-P125 WeakPolarHBondContact CA-O 3.41Å; T98-P125 PolarHBondContact OG1-O 2.81Å; A99-P125 HydrophobicContact CB-CG 4.41Å; P125-F127 HydrophobicContact CB-CD2 4.5Å; P125-F127 HydrophobicContact CB-CE2 3.95Å
126F95.6Very high93.2Very high52 Ų5256.8 Ų56.823%0.22831%0.312CS..EExtended strand (participates in β ladder)trans-142.3117.6170.5-174.2-79.6000108.1I96 Y97 I128 V143 L148I96-F126 HydrophobicContact CG2-CE2 4.15Å; I96-F126 HydrophobicContact CG2-CZ 4.05Å; Y97-F126 WeakPolarHBondContact O-CA 3.34Å; F126-I128 HydrophobicContact CE1-CB 4.34Å; F126-I128 HydrophobicContact CE1-CG2 4.27Å; F126-V143 HydrophobicContact CD2-CG1 4.03Å; F126-V143 HydrophobicContact CE1-CG1 4.37Å; F126-V143 HydrophobicContact CE2-CG1 3.79Å; F126-V143 HydrophobicContact CG-CG1 4.41Å; F126-V143 HydrophobicContact CZ-CG1 3.99Å; F126-L148 HydrophobicContact CE2-CD2 3.71Å; F126-L148 HydrophobicContact CE2-CG 4.4Å; F126-L148 HydrophobicContact CZ-CD2 4.35Å
127F95.5Very high93.2Very high139 Ų13959.7 Ų59.761%0.6133%0.333SS*.EExtended strand (participates in β ladder)trans-127.1143.5175.5-56.7-74000109.7I96 Y97 P125I96-F127 WeakPolarHBondContact CA-O 3.32Å; Y97-F127 AromaticContact CD1-CD2 3.92Å; Y97-F127 HydrophobicContact CD1-CD2 3.92Å; Y97-F127 HydrophobicContact CD1-CE2 4.5Å; Y97-F127 PolarHBondContact N-O 2.91Å; Y97-F127 PolarHBondContact O-N 3.48Å; P125-F127 HydrophobicContact CB-CD2 4.5Å; P125-F127 HydrophobicContact CB-CE2 3.95Å
128I95.1Very high93Very high33 Ų3367 Ų6717%0.16937%0.371CS..EExtended strand (participates in β ladder)trans-136.5134.2174.9-175.4164000110.5Y94 I95 I96 F126 V133 L173Y94-I128 HydrophobicContact CD1-CD1 4.29Å; I95-I128 CarbonylContact O-C 3.59Å; I95-I128 WeakPolarHBondContact O-CA 3.47Å; I96-I128 HydrophobicContact CD1-CD1 4.13Å; I96-I128 HydrophobicContact CG1-CD1 3.9Å; I96-I128 HydrophobicContact CG1-CG1 4.01Å; F126-I128 HydrophobicContact CE1-CB 4.34Å; F126-I128 HydrophobicContact CE1-CG2 4.27Å; I128-V133 HydrophobicContact CG2-CG1 4.39Å; I128-L173 HydrophobicContact CD1-CD1 4Å; I128-L173 HydrophobicContact CG2-CD1 3.94Å; I128-L173 HydrophobicContact CG2-CD2 4.27Å
129R94.1Very high92.7Very high88 Ų8869.4 Ų69.433%0.33239%0.385SS..EExtended strand (participates in β ladder)trans-121.6149.3165.7171.1-178.3175889.3107.9E91 Y94 I95E91-R129 IonicContact OE1-CZ 3.6Å; E91-R129 IonicContact OE1-NH2 3.25Å; E91-R129 PolarHBondContact OE1-NH2 3.26Å; E91-R129 IonicContact OE2-NH2 3.83Å; Y94-R129 CarbonylContact C-O 3.57Å; Y94-R129 VanDerWaalsContact CA-O 3.28Å; Y94-R129 WeakPolarHBondContact CA-O 3.25Å; I95-R129 HydrophobicContact CB-CB 4.45Å; I95-R129 PolarHBondContact N-O 2.8Å; I95-R129 PolarHBondContact O-N 3.12Å
130G93.4Very high92.5Very high14 Ų1473.6 Ų73.614%0.14441%0.413CS..SBendtrans164.1-171.5166.500000112S132 V133G130-S132 PolarHBondContact O-N 3.01Å; G130-V133 PolarHBondContact O-N 3.31Å
131P90.7Very high92.3Very high44 Ų4474.6 Ų74.629%0.28642%0.419SS..THydrogen-bonded Turntrans-45.9136.6170.4-24.927.8000112.6E91 Y94 V133E91-P131 WeakPolarHBondContact O-CG 3.46Å; Y94-P131 HydrophobicContact CD2-CG 4.31Å; Y94-P131 WeakPolarHBondContact CE1-O 3.43Å; Y94-P131 HydrophobicContact CE2-CB 4.21Å; Y94-P131 HydrophobicContact CE2-CG 3.79Å; Y94-P131 PolarHBondContact OH-O 3.16Å; Y94-P131 VanDerWaalsContact OH-O 3.08Å; P131-V133 PolarHBondContact O-N 2.89Å; P131-V133 VanDerWaalsContact O-N 3.11Å
132S84.8Confident92.2Very high97 Ų9775.2 Ų75.268%0.67842%0.422SS*.THydrogen-bonded Turntrans57.219.8177.1-49.50000116.2G130G130-S132 PolarHBondContact O-N 3.01Å
133V90.8Very high92.1Very high24 Ų2475.1 Ų75.115%0.14542%0.423CS..  trans-100.2112.7172.7-172.80000109.9Y94 I128 G130 P131 P135 L173Y94-V133 HydrophobicContact CE1-CG2 4.07Å; I128-V133 HydrophobicContact CG2-CG1 4.39Å; G130-V133 PolarHBondContact O-N 3.31Å; P131-V133 PolarHBondContact O-N 2.89Å; P131-V133 VanDerWaalsContact O-N 3.11Å; V133-P135 WeakPolarHBondContact O-CD 3.41Å; V133-L173 HydrophobicContact CG1-CD1 4.48Å; V133-L173 HydrophobicContact CG2-CD1 3.99Å
134E90.5Very high92.1Very high112 Ų11268 Ų6852%0.52340%0.398SS..  trans-61.6119.5-179.1-69.5-62.2154.800112.1G136 S137E134-G136 PolarHBondContact O-N 3.19Å; E134-S137 VanDerWaalsContact O-CB 3.29Å; E134-S137 WeakPolarHBondContact O-CB 3.44Å; E134-S137 PolarHBondContact O-N 2.98Å; E134-S137 PolarHBondContact O-OG 2.94Å
135P91.9Very high92.1Very high117 Ų11769.4 Ų69.476%0.7641%0.405SS*.THydrogen-bonded Turntrans-60134.5-178.1-25.635.3000113.2V133 S137V133-P135 WeakPolarHBondContact O-CD 3.41Å; P135-S137 PolarHBondContact O-N 3.2Å
136G89.9Confident92Very high80 Ų8070.5 Ų70.583%0.82541%0.406SS*.THydrogen-bonded Turntrans70.55.3179.500000115.1E134E134-G136 PolarHBondContact O-N 3.19Å
137S91.1Very high92Very high64 Ų6468 Ų6845%0.44840%0.395SS..  trans-66.4146.6174.662.90000112.1E134 P135E134-S137 VanDerWaalsContact O-CB 3.29Å; E134-S137 WeakPolarHBondContact O-CB 3.44Å; E134-S137 PolarHBondContact O-N 2.98Å; E134-S137 PolarHBondContact O-OG 2.94Å; P135-S137 PolarHBondContact O-N 3.2Å
138I91.1Very high92Very high154 Ų15463.1 Ų63.179%0.7938%0.375SS*.  trans-120.6125.4178.6-59.9178.1000108.8P140I138-P140 WeakPolarHBondContact O-CD 3.24Å
139V90Very high92.1Very high50 Ų5064.4 Ų64.430%0.30339%0.391SS..  trans-104.3105.4-179.81780000108.6Q141 L172 L173V139-Q141 VanDerWaalsContact C-N 3.29Å; V139-Q141 HydrophobicContact CG1-CB 4.32Å; V139-Q141 VanDerWaalsContact CG1-OE1 3.29Å; V139-Q141 PolarHBondContact O-N 3.28Å; V139-L172 HydrophobicContact CG1-CB 3.96Å; V139-L172 HydrophobicContact CG1-CD1 3.84Å; V139-L172 HydrophobicContact CG1-CG 4.43Å; V139-L173 HydrophobicContact CG2-CD2 3.94Å
140P88.9Confident92.1Very high107 Ų10760.2 Ų60.270%0.69538%0.375SS*.  trans-77.5-9.5-177.930.7-36.8000114.3I138I138-P140 WeakPolarHBondContact O-CD 3.24Å
141Q90.3Very high92.2Very high66 Ų6659.6 Ų59.631%0.30837%0.368SS..SBendtrans-73.1145.5-179-67.280.17.300112.5V139 V143 L172 W191V139-Q141 VanDerWaalsContact C-N 3.29Å; V139-Q141 HydrophobicContact CG1-CB 4.32Å; V139-Q141 VanDerWaalsContact CG1-OE1 3.29Å; V139-Q141 PolarHBondContact O-N 3.28Å; Q141-V143 PolarHBondContact O-N 3.49Å; Q141-V143 VanDerWaalsContact O-N 3.15Å; Q141-L172 HydrophobicContact CB-CD1 3.91Å; Q141-L172 HydrophobicContact CB-CD2 4.06Å; Q141-L172 HydrophobicContact CG-CD2 3.96Å; Q141-W191 HydrophobicContact CB-CB 4.37Å; Q141-W191 HydrophobicContact CB-CG 4.12Å; Q141-W191 HydrophobicContact CG-CB 4.13Å; Q141-W191 HydrophobicContact CG-CG 4.41Å
142I91.6Very high92.4Very high21 Ų2162.1 Ų62.111%0.10838%0.379CS..  trans-66.9110.1-176.4-50177.4000111.7L144 W191 R192 D193 F195 V566I142-L144 HydrophobicContact CG2-CD2 3.73Å; I142-L144 HydrophobicContact CG2-CG 4.37Å; I142-W191 PolarHBondContact O-NE1 3.1Å; I142-R192 HydrophobicContact CB-CG 4.29Å; I142-D193 WeakPolarHBondContact CD1-O 3.35Å; I142-F195 HydrophobicContact CD1-CD1 3.92Å; I142-F195 HydrophobicContact CD1-CE1 4.06Å; I142-F195 HydrophobicContact CG2-CD1 3.65Å; I142-F195 HydrophobicContact CG2-CE1 3.56Å; I142-F195 HydrophobicContact CG2-CZ 4.37Å; I142-V566 HydrophobicContact CD1-CB 3.86Å; I142-V566 HydrophobicContact CD1-CG2 4.12Å; I142-V566 HydrophobicContact CG1-CB 4.13Å; I142-V566 HydrophobicContact CG1-CG2 4.5Å
143V93.9Very high93Very high41 Ų4159.9 Ų59.925%0.24836%0.359CS..  trans-99.2139.5168.9177.60000109.8F126 Q141 D147 V169 L172F126-V143 HydrophobicContact CD2-CG1 4.03Å; F126-V143 HydrophobicContact CE1-CG1 4.37Å; F126-V143 HydrophobicContact CE2-CG1 3.79Å; F126-V143 HydrophobicContact CG-CG1 4.41Å; F126-V143 HydrophobicContact CZ-CG1 3.99Å; Q141-V143 PolarHBondContact O-N 3.49Å; Q141-V143 VanDerWaalsContact O-N 3.15Å; V143-D147 HydrophobicContact CG1-CB 4.36Å; V143-V169 HydrophobicContact CG1-CG2 3.66Å; V143-V169 HydrophobicContact CG2-CG1 4.12Å; V143-V169 HydrophobicContact CG2-CG2 4.05Å; V143-L172 HydrophobicContact CG2-CD1 4.12Å
144L94.8Very high93.1Very high28 Ų2861.2 Ų61.215%0.14737%0.365CS..  trans-121.3156.8-178.5-55.2-178.9000111.6I142 I146 D147 F195I142-L144 HydrophobicContact CG2-CD2 3.73Å; I142-L144 HydrophobicContact CG2-CG 4.37Å; L144-I146 HydrophobicContact CB-CG1 3.83Å; L144-I146 HydrophobicContact CD1-CD1 4.15Å; L144-I146 HydrophobicContact CD1-CG1 4.27Å; L144-I146 PolarHBondContact O-N 2.97Å; L144-D147 PolarHBondContact N-OD2 2.95Å; L144-D147 WeakPolarHBondContact O-CB 3.21Å; L144-D147 PolarHBondContact O-N 3.36Å; L144-F195 HydrophobicContact CD1-CB 3.69Å; L144-F195 HydrophobicContact CD1-CD2 4.13Å; L144-F195 HydrophobicContact CD1-CG 4.06Å; L144-F195 HydrophobicContact CD2-CB 4.32Å; L144-F195 HydrophobicContact CD2-CD1 4.12Å; L144-F195 HydrophobicContact CD2-CD2 3.55Å; L144-F195 HydrophobicContact CD2-CE1 4.23Å; L144-F195 HydrophobicContact CD2-CE2 3.68Å; L144-F195 HydrophobicContact CD2-CG 3.76Å; L144-F195 HydrophobicContact CD2-CZ 4.01Å
145N94.8Very high93.3Very high67 Ų6758.6 Ų58.636%0.35835%0.354SS..G310 helixtrans-60.5-21.4177.9-73.1-7.5000113.9A99 D100 D147 L148A99-N145 PolarHBondContact O-ND2 3.44Å; D100-N145 PolarHBondContact O-ND2 3.08Å; N145-D147 PolarHBondContact O-N 3.36Å; N145-L148 HydrophobicContact CB-CD1 4.5Å
146I94.1Very high93.4Very high83 Ų8356.2 Ų56.243%0.42634%0.344SS..G310 helixtrans-71.4-15.4172.361.6171.3000113.7L144 P150 D165L144-I146 HydrophobicContact CB-CG1 3.83Å; L144-I146 HydrophobicContact CD1-CD1 4.15Å; L144-I146 HydrophobicContact CD1-CG1 4.27Å; L144-I146 PolarHBondContact O-N 2.97Å; I146-P150 WeakPolarHBondContact O-CD 3.27Å; I146-D165 HydrophobicContact CD1-CB 4.09Å
147D95.5Very high93.6Very high0 Ų055.7 Ų55.70%034%0.339CS..G310 helixtrans-84.6-17.7-178.6-60.3-35.2000112.9V143 L144 N145 A149 P150 T151 G166 K167 V169 R192V143-D147 HydrophobicContact CG1-CB 4.36Å; L144-D147 PolarHBondContact N-OD2 2.95Å; L144-D147 WeakPolarHBondContact O-CB 3.21Å; L144-D147 PolarHBondContact O-N 3.36Å; N145-D147 PolarHBondContact O-N 3.36Å; D147-A149 PolarHBondContact O-N 2.9Å; D147-P150 VanDerWaalsContact O-CD 3.28Å; D147-P150 WeakPolarHBondContact O-CD 3.23Å; D147-P150 WeakPolarHBondContact O-CG 3.28Å; D147-T151 VanDerWaalsContact O-CB 3.31Å; D147-T151 WeakPolarHBondContact O-CB 3.37Å; D147-T151 PolarHBondContact O-N 3.31Å; D147-T151 PolarHBondContact O-OG1 3.47Å; D147-G166 WeakPolarHBondContact OD1-CA 3.49Å; D147-K167 VanDerWaalsContact CB-O 3.28Å; D147-K167 WeakPolarHBondContact CB-O 3.41Å; D147-K167 PolarHBondContact OD1-N 3.36Å; D147-V169 HydrophobicContact CB-CG2 3.92Å; D147-R192 IonicContact OD1-CZ 3.21Å; D147-R192 VanDerWaalsContact OD1-CZ 3.27Å; D147-R192 IonicContact OD1-NH1 3.14Å; D147-R192 PolarHBondContact OD1-NH1 2.96Å; D147-R192 IonicContact OD1-NH2 2.89Å; D147-R192 PolarHBondContact OD1-NH2 2.91Å; D147-R192 IonicContact OD2-CZ 2.86Å; D147-R192 IonicContact OD2-NH1 2.94Å; D147-R192 PolarHBondContact OD2-NH1 3.4Å; D147-R192 VanDerWaalsContact OD2-NH1 3.14Å; D147-R192 IonicContact OD2-NH2 3.27Å; D147-R192 PolarHBondContact OD2-NH2 2.89Å
148L95.4Very high93.9Very high36 Ų3657.3 Ų57.319%0.18834%0.342CS..Hα-helixtrans-58.1-48.7177.9-72.2163.3000111.8I96 T98 F126 N145 T151 I152I96-L148 HydrophobicContact CG2-CD2 3.81Å; T98-L148 HydrophobicContact CG2-CD1 4.03Å; T98-L148 HydrophobicContact CG2-CD2 4.45Å; F126-L148 HydrophobicContact CE2-CD2 3.71Å; F126-L148 HydrophobicContact CE2-CG 4.4Å; F126-L148 HydrophobicContact CZ-CD2 4.35Å; N145-L148 HydrophobicContact CB-CD1 4.5Å; L148-T151 PolarHBondContact O-N 3Å; L148-I152 WeakPolarHBondContact O-CD1 3.38Å; L148-I152 VanDerWaalsContact O-CG1 3.27Å; L148-I152 WeakPolarHBondContact O-CG1 3.5Å; L148-I152 PolarHBondContact O-N 3.24Å
149A95.3Very high93.9Very high60 Ų6057.8 Ų57.850%0.49635%0.346SS..Hα-helixtrans-60.3-53-179.400000113.5D147 T151 I152 L153D147-A149 PolarHBondContact O-N 2.9Å; A149-T151 VanDerWaalsContact C-N 3.31Å; A149-T151 PolarHBondContact O-N 3.24Å; A149-I152 PolarHBondContact O-N 3.47Å; A149-L153 WeakPolarHBondContact O-CG 3.1Å; A149-L153 PolarHBondContact O-N 3.04Å; A149-L153 VanDerWaalsContact O-N 3.11Å
150P95.7Very high94Very high0 Ų056.9 Ų56.90%034%0.341CS..Hα-helixtrans-67-28.917626.1-34.1000113.1I146 D147 L153 D154 T160 V164I146-P150 WeakPolarHBondContact O-CD 3.27Å; D147-P150 VanDerWaalsContact O-CD 3.28Å; D147-P150 WeakPolarHBondContact O-CD 3.23Å; D147-P150 WeakPolarHBondContact O-CG 3.28Å; P150-L153 PolarHBondContact O-N 2.74Å; P150-D154 WeakPolarHBondContact O-CB 3.39Å; P150-D154 PolarHBondContact O-N 3.26Å; P150-T160 HydrophobicContact CB-CG2 3.65Å; P150-T160 VanDerWaalsContact CB-OG1 3.31Å; P150-T160 WeakPolarHBondContact CB-OG1 3.2Å; P150-V164 HydrophobicContact CB-CG1 4.42Å; P150-V164 HydrophobicContact CG-CG1 4.18Å
151T95.1Very high94.2Very high1 Ų154.3 Ų54.31%0.00632%0.324CS..Hα-helixtrans-65.2-43.3173.1-53.60000111.5D147 L148 A149 L153 D154 I155 S168 V169 L170D147-T151 VanDerWaalsContact O-CB 3.31Å; D147-T151 WeakPolarHBondContact O-CB 3.37Å; D147-T151 PolarHBondContact O-N 3.31Å; D147-T151 PolarHBondContact O-OG1 3.47Å; L148-T151 PolarHBondContact O-N 3Å; A149-T151 VanDerWaalsContact C-N 3.31Å; A149-T151 PolarHBondContact O-N 3.24Å; T151-L153 VanDerWaalsContact C-N 3.3Å; T151-L153 PolarHBondContact O-N 3.15Å; T151-D154 PolarHBondContact O-N 2.9Å; T151-I155 HydrophobicContact CG2-CD1 4.12Å; T151-I155 VanDerWaalsContact O-CG1 3.29Å; T151-I155 WeakPolarHBondContact O-CG1 3.42Å; T151-I155 PolarHBondContact O-N 2.7Å; T151-S168 WeakPolarHBondContact OG1-CA 3.02Å; T151-V169 HydrophobicContact CG2-CB 4.17Å; T151-V169 WeakPolarHBondContact OG1-CG2 3.46Å; T151-V169 PolarHBondContact OG1-N 2.91Å; T151-L170 HydrophobicContact CG2-CD2 4.13Å; T151-L170 HydrophobicContact CG2-CG 4.17Å
152I95.7Very high94.2Very high97 Ų9756 Ų5650%0.49734%0.34SS..Hα-helixtrans-66.5-32.7177.5-68.2163.4000111.5L148 A149 A156L148-I152 WeakPolarHBondContact O-CD1 3.38Å; L148-I152 VanDerWaalsContact O-CG1 3.27Å; L148-I152 WeakPolarHBondContact O-CG1 3.5Å; L148-I152 PolarHBondContact O-N 3.24Å; A149-I152 PolarHBondContact O-N 3.47Å; I152-A156 WeakPolarHBondContact O-CB 3.45Å; I152-A156 PolarHBondContact O-N 3.06Å; I152-A156 VanDerWaalsContact O-N 3.14Å
153L95.8Very high94.2Very high50 Ų5059.5 Ų59.526%0.26236%0.359SS..Hα-helixtrans-67.5-44.9171.8-68.8174.3000112A149 P150 T151 I155 A156 G157 L158A149-L153 WeakPolarHBondContact O-CG 3.1Å; A149-L153 PolarHBondContact O-N 3.04Å; A149-L153 VanDerWaalsContact O-N 3.11Å; P150-L153 PolarHBondContact O-N 2.74Å; T151-L153 VanDerWaalsContact C-N 3.3Å; T151-L153 PolarHBondContact O-N 3.15Å; L153-I155 PolarHBondContact O-N 2.89Å; L153-A156 CarbonylContact O-C 3.45Å; L153-A156 WeakPolarHBondContact O-CA 3.43Å; L153-A156 PolarHBondContact O-N 2.99Å; L153-G157 PolarHBondContact O-N 3.21Å; L153-G157 VanDerWaalsContact O-N 3.16Å; L153-L158 CarbonylContact C-O 3.42Å; L153-L158 HydrophobicContact CB-CB 4.28Å; L153-L158 HydrophobicContact CD2-CB 4.12Å; L153-L158 HydrophobicContact CD2-CD1 3.99Å; L153-L158 PolarHBondContact O-N 3.12Å
154D93.9Very high94.1Very high52 Ų5259.4 Ų59.428%0.27836%0.359SS..Hα-helixtrans-61.4-43.1177.6-143.717.5000110.8P150 T151 A156 G157 S168 L170 K171P150-D154 WeakPolarHBondContact O-CB 3.39Å; P150-D154 PolarHBondContact O-N 3.26Å; T151-D154 PolarHBondContact O-N 2.9Å; D154-A156 VanDerWaalsContact C-N 3.26Å; D154-A156 PolarHBondContact O-N 2.83Å; D154-G157 PolarHBondContact O-N 3.41Å; D154-S168 VanDerWaalsContact CB-OG 3.28Å; D154-S168 WeakPolarHBondContact CB-OG 3.29Å; D154-S168 WeakPolarHBondContact OD2-CB 3.23Å; D154-S168 PolarHBondContact OD2-OG 3.43Å; D154-L170 HydrophobicContact CB-CD1 3.96Å; D154-L170 HydrophobicContact CB-CG 4.49Å; D154-K171 WeakPolarHBondContact OD2-CE 3.42Å; D154-K171 IonicContact OD2-NZ 3.76Å
155I94.2Very high94.1Very high57 Ų5761 Ų6129%0.29237%0.368SS..Hα-helixtrans-58.1-37.1171.8-69.9167.8000111.7Y94 T151 L153 G157 L170Y94-I155 HydrophobicContact CD1-CD1 4.02Å; Y94-I155 HydrophobicContact CD2-CB 4.48Å; Y94-I155 HydrophobicContact CD2-CD1 4.04Å; Y94-I155 HydrophobicContact CD2-CG1 4.12Å; Y94-I155 HydrophobicContact CD2-CG2 3.52Å; Y94-I155 HydrophobicContact CE1-CD1 4.41Å; Y94-I155 HydrophobicContact CE1-CG1 4.49Å; Y94-I155 HydrophobicContact CE2-CB 4.48Å; Y94-I155 HydrophobicContact CE2-CD1 4.43Å; Y94-I155 HydrophobicContact CE2-CG1 4.07Å; Y94-I155 HydrophobicContact CE2-CG2 3.74Å; Y94-I155 HydrophobicContact CG-CD1 3.8Å; Y94-I155 HydrophobicContact CG-CG1 4.34Å; Y94-I155 HydrophobicContact CG-CG2 4.32Å; T151-I155 HydrophobicContact CG2-CD1 4.12Å; T151-I155 VanDerWaalsContact O-CG1 3.29Å; T151-I155 WeakPolarHBondContact O-CG1 3.42Å; T151-I155 PolarHBondContact O-N 2.7Å; L153-I155 PolarHBondContact O-N 2.89Å; I155-G157 VanDerWaalsContact C-N 3.27Å; I155-G157 PolarHBondContact O-N 2.98Å; I155-L170 HydrophobicContact CD1-CD2 4.34Å; I155-L170 HydrophobicContact CG1-CD1 3.89Å; I155-L170 HydrophobicContact CG1-CD2 3.97Å; I155-L170 HydrophobicContact CG1-CG 4.27Å
156A94.8Very high93.9Very high67 Ų6757.9 Ų57.955%0.55435%0.351SS*.THydrogen-bonded Turntrans-82.22.6178.200000114.1I152 L153 D154 L158I152-A156 WeakPolarHBondContact O-CB 3.45Å; I152-A156 PolarHBondContact O-N 3.06Å; I152-A156 VanDerWaalsContact O-N 3.14Å; L153-A156 CarbonylContact O-C 3.45Å; L153-A156 WeakPolarHBondContact O-CA 3.43Å; L153-A156 PolarHBondContact O-N 2.99Å; D154-A156 VanDerWaalsContact C-N 3.26Å; D154-A156 PolarHBondContact O-N 2.83Å; A156-L158 VanDerWaalsContact C-N 3.32Å; A156-L158 HydrophobicContact CB-CD1 4.17Å; A156-L158 HydrophobicContact CB-CG 4.18Å
157G94.3Very high93.8Very high69 Ų6956.1 Ų56.171%0.71134%0.34SS*.THydrogen-bonded Turntrans69.226.1-17600000114.1L153 D154 I155L153-G157 PolarHBondContact O-N 3.21Å; L153-G157 VanDerWaalsContact O-N 3.16Å; D154-G157 PolarHBondContact O-N 3.41Å; I155-G157 VanDerWaalsContact C-N 3.27Å; I155-G157 PolarHBondContact O-N 2.98Å
158L95.8Very high93.7Very high98 Ų9856.3 Ų56.351%0.51334%0.341SS..  trans-111.2135.4-176.8-61.9177.8000111.9L153 A156 T160L153-L158 CarbonylContact C-O 3.42Å; L153-L158 HydrophobicContact CB-CB 4.28Å; L153-L158 HydrophobicContact CD2-CB 4.12Å; L153-L158 HydrophobicContact CD2-CD1 3.99Å; L153-L158 PolarHBondContact O-N 3.12Å; A156-L158 VanDerWaalsContact C-N 3.32Å; A156-L158 HydrophobicContact CB-CD1 4.17Å; A156-L158 HydrophobicContact CB-CG 4.18Å; L158-T160 PolarHBondContact O-N 2.89Å
159D92.4Very high93.6Very high163 Ų16354.7 Ų54.787%0.87233%0.333SS*.PPolyproline II helixtrans-59.3134.3174.2-82.1-54.5000112.3P161D159-P161 WeakPolarHBondContact O-CD 3.33Å
160T92.6Very high93.3Very high32 Ų3253.3 Ų53.320%0.19632%0.317CS..PPolyproline II helixtrans-70124.2171.1-67.70000110.4P150 L158 V164 Y622P150-T160 HydrophobicContact CB-CG2 3.65Å; P150-T160 VanDerWaalsContact CB-OG1 3.31Å; P150-T160 WeakPolarHBondContact CB-OG1 3.2Å; L158-T160 PolarHBondContact O-N 2.89Å; T160-V164 HydrophobicContact CG2-CB 4.09Å; T160-V164 HydrophobicContact CG2-CG1 4.25Å; T160-Y622 HydrophobicContact CG2-CD1 4.32Å; T160-Y622 HydrophobicContact CG2-CE1 4.45Å
161P93.2Very high92.8Very high52 Ų5258.9 Ų58.934%0.33834%0.342SS..PPolyproline II helixtrans-56.6140.9175.8-25.634.3000112.5D159 D163 V164D159-P161 WeakPolarHBondContact O-CD 3.33Å; P161-D163 VanDerWaalsContact CB-OD1 3.23Å; P161-D163 WeakPolarHBondContact CB-OD1 3.2Å; P161-D163 PolarHBondContact O-N 3.08Å; P161-D163 VanDerWaalsContact O-N 3.16Å; P161-V164 HydrophobicContact CB-CG2 4.13Å; P161-V164 HydrophobicContact CG-CG2 4.34Å; P161-V164 PolarHBondContact O-N 3.18Å; P161-V164 VanDerWaalsContact O-N 3.13Å
162P89.8Confident92.5Very high101 Ų10159.5 Ų59.566%0.65635%0.345SS*.THydrogen-bonded Turntrans-69.8-14.6-17129.7-36.7000114.1G621P162-G621 VanDerWaalsContact O-CA 3.3Å; P162-G621 WeakPolarHBondContact O-CA 3.34Å
163D91Very high92Very high95 Ų9555.9 Ų55.951%0.50833%0.326SS..THydrogen-bonded Turntrans-91.2-4.7176.961.4-45.2000113.9P161P161-D163 VanDerWaalsContact CB-OD1 3.23Å; P161-D163 WeakPolarHBondContact CB-OD1 3.2Å; P161-D163 PolarHBondContact O-N 3.08Å; P161-D163 VanDerWaalsContact O-N 3.16Å
164V92.9Very high91Very high39 Ų3958.1 Ų58.124%0.23634%0.338CS..  trans-77.7127.4171171.30000109.6P150 T160 P161 G621 Y622P150-V164 HydrophobicContact CB-CG1 4.42Å; P150-V164 HydrophobicContact CG-CG1 4.18Å; T160-V164 HydrophobicContact CG2-CB 4.09Å; T160-V164 HydrophobicContact CG2-CG1 4.25Å; P161-V164 HydrophobicContact CB-CG2 4.13Å; P161-V164 HydrophobicContact CG-CG2 4.34Å; P161-V164 PolarHBondContact O-N 3.18Å; P161-V164 VanDerWaalsContact O-N 3.13Å; V164-G621 CarbonylContact O-C 3.59Å; V164-Y622 WeakPolarHBondContact O-CB 3.33Å; V164-Y622 PolarHBondContact O-N 3.36Å
165D93Very high89.5Confident63 Ų6359.2 Ų59.234%0.33735%0.348SS..  trans-77.7-22.5-176.3-54.8-47.5000113.8I146 G621 Y622 C625 N626I146-D165 HydrophobicContact CD1-CB 4.09Å; D165-G621 WeakPolarHBondContact OD1-CA 3.34Å; D165-G621 PolarHBondContact OD1-N 3.15Å; D165-Y622 WeakPolarHBondContact O-CA 3.28Å; D165-C625 HydrophobicContact CB-CB 4.04Å; D165-C625 PolarHBondContact OD1-SG 3.14Å; D165-N626 PolarHBondContact O-ND2 3.15Å
166G92.6Very high87.8Confident0 Ų062 Ų620%036%0.36CS..  trans-80.9167179.400000114.4D147 Y622D147-G166 WeakPolarHBondContact OD1-CA 3.49Å; G166-Y622 VanDerWaalsContact O-CB 3.26Å; G166-Y622 WeakPolarHBondContact O-CB 3.43Å
167K91.3Very high85.7Confident46 Ų4668 Ų6820%0.237%0.374CS..  trans-125.3141.6175.3-67175.4173.9169.50110.4D147 V169 W191 Y622 N626D147-K167 VanDerWaalsContact CB-O 3.28Å; D147-K167 WeakPolarHBondContact CB-O 3.41Å; D147-K167 PolarHBondContact OD1-N 3.36Å; K167-V169 PolarHBondContact O-N 3.13Å; K167-W191 HydrophobicContact CB-CH2 3.62Å; K167-W191 HydrophobicContact CB-CZ2 4.34Å; K167-W191 HydrophobicContact CB-CZ3 3.9Å; K167-W191 HydrophobicContact CD-CZ3 4.34Å; K167-Y622 WeakPolarHBondContact CE-O 3.28Å; K167-Y622 HydrophobicContact CG-CD2 4.28Å; K167-Y622 HydrophobicContact CG-CG 4.37Å; K167-N626 HydrophobicContact CD-CB 4.13Å; K167-N626 PolarHBondContact NZ-O 3.3Å
168S93.1Very high83.3Confident4 Ų470.9 Ų70.93%0.02838%0.38CS..  trans-57.5130.2173.5170.50000112.4T151 D154 L170 W191T151-S168 WeakPolarHBondContact OG1-CA 3.02Å; D154-S168 VanDerWaalsContact CB-OG 3.28Å; D154-S168 WeakPolarHBondContact CB-OG 3.29Å; D154-S168 WeakPolarHBondContact OD2-CB 3.23Å; D154-S168 PolarHBondContact OD2-OG 3.43Å; S168-L170 VanDerWaalsContact C-N 3.34Å; S168-L170 PolarHBondContact OG-N 2.84Å; S168-W191 WeakPolarHBondContact O-CH2 3.06Å
169V92.9Very high81.1Confident3 Ų369.1 Ų69.12%0.01839%0.386CS..THydrogen-bonded Turntrans-75-20.2179.7178.90000112.1V143 D147 T151 K167 K171 L172 L173V143-V169 HydrophobicContact CG1-CG2 3.66Å; V143-V169 HydrophobicContact CG2-CG1 4.12Å; V143-V169 HydrophobicContact CG2-CG2 4.05Å; D147-V169 HydrophobicContact CB-CG2 3.92Å; T151-V169 HydrophobicContact CG2-CB 4.17Å; T151-V169 WeakPolarHBondContact OG1-CG2 3.46Å; T151-V169 PolarHBondContact OG1-N 2.91Å; K167-V169 PolarHBondContact O-N 3.13Å; V169-K171 PolarHBondContact O-N 3.46Å; V169-L172 HydrophobicContact CG1-CD1 4.44Å; V169-L172 WeakPolarHBondContact O-CA 3.49Å; V169-L172 WeakPolarHBondContact O-CB 3.2Å; V169-L172 PolarHBondContact O-N 2.99Å; V169-L173 HydrophobicContact CG1-CG 4.5Å; V169-L173 PolarHBondContact O-N 2.92Å
170L89.5Confident78.9Confident31 Ų3167.8 Ų67.816%0.16238%0.378CS..Hα-helixtrans-52.9-33.7-179.4-62.5-170.2000112.6Y94 T151 D154 I155 S168 L172 L173 D174Y94-L170 HydrophobicContact CE1-CD2 4.29Å; T151-L170 HydrophobicContact CG2-CD2 4.13Å; T151-L170 HydrophobicContact CG2-CG 4.17Å; D154-L170 HydrophobicContact CB-CD1 3.96Å; D154-L170 HydrophobicContact CB-CG 4.49Å; I155-L170 HydrophobicContact CD1-CD2 4.34Å; I155-L170 HydrophobicContact CG1-CD1 3.89Å; I155-L170 HydrophobicContact CG1-CD2 3.97Å; I155-L170 HydrophobicContact CG1-CG 4.27Å; S168-L170 VanDerWaalsContact C-N 3.34Å; S168-L170 PolarHBondContact OG-N 2.84Å; L170-L172 PolarHBondContact O-N 3.2Å; L170-L173 HydrophobicContact CD2-CD1 4.21Å; L170-L173 CarbonylContact O-C 3.48Å; L170-L173 WeakPolarHBondContact O-CA 3.34Å; L170-L173 WeakPolarHBondContact O-CB 3.44Å; L170-L173 PolarHBondContact O-N 2.77Å; L170-D174 PolarHBondContact O-N 3.31Å
171K85.4Confident77.2Confident117 Ų11777.9 Ų77.951%0.50941%0.413SS..Hα-helixtrans-65.4-23.6179.3-67.1162.5-169171.90113D154 V169 D174 K189D154-K171 WeakPolarHBondContact OD2-CE 3.42Å; D154-K171 IonicContact OD2-NZ 3.76Å; V169-K171 PolarHBondContact O-N 3.46Å; K171-D174 WeakPolarHBondContact CA-OD2 3.43Å; K171-K189 WeakPolarHBondContact O-CD 3.5Å; K171-K189 PolarHBondContact O-NZ 3.15Å
172L87.5Confident75.5Confident13 Ų1384.8 Ų84.87%0.06844%0.438CS..Hα-helixtrans-79.1-30.6169.2-63177.1000112.2V139 Q141 V143 V169 L170 K189 W191V139-L172 HydrophobicContact CG1-CB 3.96Å; V139-L172 HydrophobicContact CG1-CD1 3.84Å; V139-L172 HydrophobicContact CG1-CG 4.43Å; Q141-L172 HydrophobicContact CB-CD1 3.91Å; Q141-L172 HydrophobicContact CB-CD2 4.06Å; Q141-L172 HydrophobicContact CG-CD2 3.96Å; V143-L172 HydrophobicContact CG2-CD1 4.12Å; V169-L172 HydrophobicContact CG1-CD1 4.44Å; V169-L172 WeakPolarHBondContact O-CA 3.49Å; V169-L172 WeakPolarHBondContact O-CB 3.2Å; V169-L172 PolarHBondContact O-N 2.99Å; L170-L172 PolarHBondContact O-N 3.2Å; L172-K189 HydrophobicContact CD2-CB 4.46Å; L172-K189 HydrophobicContact CD2-CD 4.48Å; L172-K189 PolarHBondContact O-NZ 3Å; L172-W191 HydrophobicContact CD1-CD2 3.88Å; L172-W191 HydrophobicContact CD1-CE3 4.25Å; L172-W191 HydrophobicContact CD1-CG 4.35Å; L172-W191 HydrophobicContact CD1-CH2 4.13Å; L172-W191 HydrophobicContact CD1-CZ2 3.75Å; L172-W191 HydrophobicContact CD1-CZ3 4.37Å; L172-W191 HydrophobicContact CD2-CB 4.17Å; L172-W191 HydrophobicContact CD2-CD2 3.83Å; L172-W191 HydrophobicContact CD2-CE3 3.83Å; L172-W191 HydrophobicContact CD2-CG 4Å; L172-W191 HydrophobicContact CD2-CZ3 4.44Å; L172-W191 HydrophobicContact CG-CD2 4.05Å; L172-W191 HydrophobicContact CG-CE3 3.96Å; L172-W191 HydrophobicContact CG-CH2 4.28Å; L172-W191 HydrophobicContact CG-CZ2 4.35Å; L172-W191 HydrophobicContact CG-CZ3 4.09Å
173L85.4Confident73.6Confident22 Ų2290.6 Ų90.612%0.11545%0.447CS..Hα-helixtrans-81.3-29.2-179.4-51.6178.1000113.4I128 V133 V139 V169 L170 P175I128-L173 HydrophobicContact CD1-CD1 4Å; I128-L173 HydrophobicContact CG2-CD1 3.94Å; I128-L173 HydrophobicContact CG2-CD2 4.27Å; V133-L173 HydrophobicContact CG1-CD1 4.48Å; V133-L173 HydrophobicContact CG2-CD1 3.99Å; V139-L173 HydrophobicContact CG2-CD2 3.94Å; V169-L173 HydrophobicContact CG1-CG 4.5Å; V169-L173 PolarHBondContact O-N 2.92Å; L170-L173 HydrophobicContact CD2-CD1 4.21Å; L170-L173 CarbonylContact O-C 3.48Å; L170-L173 WeakPolarHBondContact O-CA 3.34Å; L170-L173 WeakPolarHBondContact O-CB 3.44Å; L170-L173 PolarHBondContact O-N 2.77Å; L173-P175 VanDerWaalsContact O-N 3.15Å
174D74.8Confident71.6Confident96 Ų9692.2 Ų92.251%0.51346%0.46SS..SBendtrans-40.7117.8176.8-84.1-40000111.7L170 K171 E176 K189L170-D174 PolarHBondContact O-N 3.31Å; K171-D174 WeakPolarHBondContact CA-OD2 3.43Å; D174-E176 PolarHBondContact O-N 2.9Å; D174-K189 PolarHBondContact O-NZ 3.09Å
175P63.5Low69.4Low75 Ų7597 Ų9749%0.48749%0.485SS..  trans-60.5136.8178.523.1-32.6000110.2L173 K177L173-P175 VanDerWaalsContact O-N 3.15Å; P175-K177 PolarHBondContact O-N 2.79Å
176E57.8Low67.6Low116 Ų116102.4 Ų102.454%0.54251%0.505SS..  trans-62.7103.3178-73.3-159.415700109.5D174 P178D174-E176 PolarHBondContact O-N 2.9Å; E176-P178 VanDerWaalsContact O-N 3.14Å
177K50.4Low65.8Low194 Ų194110.5 Ų110.584%0.84354%0.54SS*.  trans-52122.8172.1-70.4-174.4178.3-179.40108.1P175 G179P175-K177 PolarHBondContact O-N 2.79Å; K177-G179 VanDerWaalsContact C-N 3.34Å; K177-G179 PolarHBondContact O-N 3.07Å
178P43.7Very low64.4Low128 Ų128110.8 Ų110.883%0.83155%0.551SS**  trans-67.892.5-172.325.6-34.3000110.4E176E176-P178 VanDerWaalsContact O-N 3.14Å
179G49.7Very low63.3Low62 Ų62113.6 Ų113.664%0.63956%0.563SS**  trans-58.8143.5172.500000110.2K177 R181K177-G179 VanDerWaalsContact C-N 3.34Å; K177-G179 PolarHBondContact O-N 3.07Å; G179-R181 PolarHBondContact O-N 2.9Å
180N47.2Very low62.5Low134 Ų134117.8 Ų117.872%0.71758%0.584SS**  trans-40.1128-175.1-64-6.7000112.1F182 R183N180-F182 PolarHBondContact O-N 3.49Å; N180-R183 PolarHBondContact O-N 3.33Å
181R55.7Low62.4Low244 Ų244117.2 Ų117.292%0.92158%0.58SS**THydrogen-bonded Turntrans-51.4-10.8-173.3-67.8-179.7176.2170.2-1.8115.9G179G179-R181 PolarHBondContact O-N 2.9Å
182F58.1Low62.6Low197 Ų197112 Ų11286%0.86456%0.557SS**THydrogen-bonded Turntrans-89.88176.6-55.1-75.4000114.6N180N180-F182 PolarHBondContact O-N 3.49Å
183R49.8Very low62.7Low223 Ų223112.4 Ų112.484%0.84256%0.559SS**  trans-123.692.9170.5-72-172.4175.1-178.5-0.9110.8N180 N185N180-R183 PolarHBondContact O-N 3.33Å; R183-N185 PolarHBondContact O-N 3.11Å
184T50Low63.1Low129 Ų129111.6 Ų111.679%0.79156%0.555SS**  trans-65.4-21.3177.644.50000114.2K186T184-K186 PolarHBondContact O-N 3.01Å
185N46.8Very low64Low141 Ų141108.6 Ų108.675%0.75454%0.538SS*.  trans-7487.5179.5-68.20.7000111.2R183 K187R183-N185 PolarHBondContact O-N 3.11Å; N185-K187 PolarHBondContact O-N 2.91Å
186K55.3Low65.5Low176 Ų176107.4 Ų107.477%0.76553%0.527SS*.  trans-50122163-66.5-173.9177.1-172.40109.1T184 A188T184-K186 PolarHBondContact O-N 3.01Å; K186-A188 PolarHBondContact O-N 3.41Å
187K54.1Low67.2Low170 Ų170102.8 Ų102.874%0.73951%0.507SS*.  trans-84.497.3172.8-76.5-165.1173-166.90108.7N185 K189N185-K187 PolarHBondContact O-N 2.91Å; K187-K189 PolarHBondContact O-N 3.16Å
188A61.3Low69.2Low51 Ų5197.3 Ų97.342%0.42148%0.484SS..  trans-47.6130.3173.800000110.9K186 I190K186-A188 PolarHBondContact O-N 3.41Å; A188-I190 PolarHBondContact O-N 2.85Å; A188-I190 VanDerWaalsContact O-N 3.11Å
189K69.9Low71.4Confident63 Ų6394.2 Ų94.227%0.27446%0.456SS..  trans-60.7115.1-179.7-66.2-172.9174.8-1670109.6K171 L172 D174 K187 W191K171-K189 WeakPolarHBondContact O-CD 3.5Å; K171-K189 PolarHBondContact O-NZ 3.15Å; L172-K189 HydrophobicContact CD2-CB 4.46Å; L172-K189 HydrophobicContact CD2-CD 4.48Å; L172-K189 PolarHBondContact O-NZ 3Å; D174-K189 PolarHBondContact O-NZ 3.09Å; K187-K189 PolarHBondContact O-N 3.16Å; K189-W191 PolarHBondContact O-N 3.27Å
190I76.4Confident72.9Confident92 Ų9293.6 Ų93.647%0.47245%0.449SS..  trans-69100.1-175.9-56.8176.2000109.6A188 R628A188-I190 PolarHBondContact O-N 2.85Å; A188-I190 VanDerWaalsContact O-N 3.11Å; I190-R628 HydrophobicContact CG2-CB 4.45Å; I190-R628 HydrophobicContact CG2-CG 4.1Å
191W87.4Confident73.6Confident18 Ų1895.2 Ų95.27%0.06845%0.45CS..  trans-120.3-179.3178.3-162.1-106.7000111.4Q141 I142 K167 S168 L172 K189 P629Q141-W191 HydrophobicContact CB-CB 4.37Å; Q141-W191 HydrophobicContact CB-CG 4.12Å; Q141-W191 HydrophobicContact CG-CB 4.13Å; Q141-W191 HydrophobicContact CG-CG 4.41Å; I142-W191 PolarHBondContact O-NE1 3.1Å; K167-W191 HydrophobicContact CB-CH2 3.62Å; K167-W191 HydrophobicContact CB-CZ2 4.34Å; K167-W191 HydrophobicContact CB-CZ3 3.9Å; K167-W191 HydrophobicContact CD-CZ3 4.34Å; S168-W191 WeakPolarHBondContact O-CH2 3.06Å; L172-W191 HydrophobicContact CD1-CD2 3.88Å; L172-W191 HydrophobicContact CD1-CE3 4.25Å; L172-W191 HydrophobicContact CD1-CG 4.35Å; L172-W191 HydrophobicContact CD1-CH2 4.13Å; L172-W191 HydrophobicContact CD1-CZ2 3.75Å; L172-W191 HydrophobicContact CD1-CZ3 4.37Å; L172-W191 HydrophobicContact CD2-CB 4.17Å; L172-W191 HydrophobicContact CD2-CD2 3.83Å; L172-W191 HydrophobicContact CD2-CE3 3.83Å; L172-W191 HydrophobicContact CD2-CG 4Å; L172-W191 HydrophobicContact CD2-CZ3 4.44Å; L172-W191 HydrophobicContact CG-CD2 4.05Å; L172-W191 HydrophobicContact CG-CE3 3.96Å; L172-W191 HydrophobicContact CG-CH2 4.28Å; L172-W191 HydrophobicContact CG-CZ2 4.35Å; L172-W191 HydrophobicContact CG-CZ3 4.09Å; K189-W191 PolarHBondContact O-N 3.27Å; W191-P629 VanDerWaalsContact O-CD 3.25Å; W191-P629 WeakPolarHBondContact O-CD 3.24Å; W191-P629 WeakPolarHBondContact O-CG 3.29Å
192R89.4Confident73.5Confident7 Ų791.4 Ų91.43%0.02644%0.441CS..  trans-75.3136.9172.887.5-156.777.8-177.12.3110I142 D147 N626I142-R192 HydrophobicContact CB-CG 4.29Å; D147-R192 IonicContact OD1-CZ 3.21Å; D147-R192 VanDerWaalsContact OD1-CZ 3.27Å; D147-R192 IonicContact OD1-NH1 3.14Å; D147-R192 PolarHBondContact OD1-NH1 2.96Å; D147-R192 IonicContact OD1-NH2 2.89Å; D147-R192 PolarHBondContact OD1-NH2 2.91Å; D147-R192 IonicContact OD2-CZ 2.86Å; D147-R192 IonicContact OD2-NH1 2.94Å; D147-R192 PolarHBondContact OD2-NH1 3.4Å; D147-R192 VanDerWaalsContact OD2-NH1 3.14Å; D147-R192 IonicContact OD2-NH2 3.27Å; D147-R192 PolarHBondContact OD2-NH2 2.89Å; R192-N626 HydrophobicContact CB-CB 4.35Å; R192-N626 WeakPolarHBondContact CD-OD1 3.35Å; R192-N626 PolarHBondContact NE-OD1 3.08Å; R192-N626 VanDerWaalsContact NE-OD1 3.11Å; R192-N626 PolarHBondContact NH1-OD1 3.12Å
193D90.9Very high72.9Confident23 Ų2389.3 Ų89.312%0.12344%0.438CS..SBendtrans-99.7-13.916755.76.4000112.5I142 T565 V566 N567 P629I142-D193 WeakPolarHBondContact CD1-O 3.35Å; D193-T565 CarbonylContact O-C 3.54Å; D193-T565 WeakPolarHBondContact O-CA 3.28Å; D193-V566 PolarHBondContact O-N 3.41Å; D193-N567 HydrophobicContact CB-CB 3.92Å; D193-P629 HydrophobicContact CB-CG 4.36Å; D193-P629 WeakPolarHBondContact OD2-CB 3.42Å
194T92.5Very high72.4Confident4 Ų489.7 Ų89.73%0.02544%0.439CS..EExtended strand (participates in β ladder)trans-137.2143.6-169.4-44.50000110.8L563 R564 T565 Q612 L616T194-L563 HydrophobicContact CG2-CD1 3.39Å; T194-L563 HydrophobicContact CG2-CD2 4.2Å; T194-L563 HydrophobicContact CG2-CG 3.55Å; T194-R564 WeakPolarHBondContact CA-O 3.47Å; T194-T565 WeakPolarHBondContact CG2-OG1 3.42Å; T194-Q612 PolarHBondContact OG1-NE2 2.85Å; T194-L616 HydrophobicContact CG2-CD1 4.27Å
195F94Very high71.8Confident33 Ų3393.2 Ų93.215%0.14544%0.443CS..EExtended strand (participates in β ladder)trans-146.2160.1173.967.4-78.8000113.8I142 L144 V197 R564I142-F195 HydrophobicContact CD1-CD1 3.92Å; I142-F195 HydrophobicContact CD1-CE1 4.06Å; I142-F195 HydrophobicContact CG2-CD1 3.65Å; I142-F195 HydrophobicContact CG2-CE1 3.56Å; I142-F195 HydrophobicContact CG2-CZ 4.37Å; L144-F195 HydrophobicContact CD1-CB 3.69Å; L144-F195 HydrophobicContact CD1-CD2 4.13Å; L144-F195 HydrophobicContact CD1-CG 4.06Å; L144-F195 HydrophobicContact CD2-CB 4.32Å; L144-F195 HydrophobicContact CD2-CD1 4.12Å; L144-F195 HydrophobicContact CD2-CD2 3.55Å; L144-F195 HydrophobicContact CD2-CE1 4.23Å; L144-F195 HydrophobicContact CD2-CE2 3.68Å; L144-F195 HydrophobicContact CD2-CG 3.76Å; L144-F195 HydrophobicContact CD2-CZ 4.01Å; F195-V197 HydrophobicContact CD2-CG2 3.96Å; F195-V197 HydrophobicContact CE2-CG2 3.52Å; F195-V197 HydrophobicContact CZ-CG2 4.41Å; F195-R564 HydrophobicContact CD1-CB 4Å; F195-R564 HydrophobicContact CD1-CG 4.31Å; F195-R564 WeakPolarHBondContact CD1-O 3.33Å; F195-R564 HydrophobicContact CE1-CB 3.58Å; F195-R564 HydrophobicContact CE1-CG 3.46Å; F195-R564 VanDerWaalsContact CE1-CG 3.46Å; F195-R564 HydrophobicContact CE2-CB 4.15Å; F195-R564 HydrophobicContact CE2-CG 4.5Å; F195-R564 HydrophobicContact CG-CB 4.48Å; F195-R564 HydrophobicContact CZ-CB 3.68Å; F195-R564 HydrophobicContact CZ-CG 3.59Å; F195-R564 PolarHBondContact N-O 2.87Å; F195-R564 PolarHBondContact O-N 2.81Å
196L94.7Very high71Confident50 Ų5093.9 Ų93.926%0.26244%0.439SS..EExtended strand (participates in β ladder)trans-87129.7173.2175.966.4000110.5E198 W561 C562 L613 L616 R617L196-E198 HydrophobicContact CD1-CB 4.35Å; L196-E198 HydrophobicContact CD2-CB 4.5Å; L196-E198 HydrophobicContact CD2-CG 4.33Å; L196-E198 HydrophobicContact CG-CB 4.33Å; L196-W561 HydrophobicContact CD1-CB 4.23Å; L196-C562 WeakPolarHBondContact CA-O 3.2Å; L196-L613 HydrophobicContact CD1-CD1 3.65Å; L196-L616 HydrophobicContact CB-CB 4.17Å; L196-R617 HydrophobicContact CD1-CG 3.83Å; L196-R617 HydrophobicContact CD2-CG 3.75Å; L196-R617 HydrophobicContact CG-CG 4.49Å
197V94.5Very high70.2Confident19 Ų1994.9 Ų94.912%0.11545%0.447CS..EExtended strand (participates in β ladder)trans-109.1123.9159.8176.90000107.1I122 F195 Y560 W561 C562I122-V197 HydrophobicContact CD1-CG2 3.95Å; I122-V197 HydrophobicContact CG2-CG1 3.86Å; I122-V197 HydrophobicContact CG2-CG2 4.45Å; F195-V197 HydrophobicContact CD2-CG2 3.96Å; F195-V197 HydrophobicContact CE2-CG2 3.52Å; F195-V197 HydrophobicContact CZ-CG2 4.41Å; V197-Y560 HydrophobicContact CG1-CE2 4.29Å; V197-W561 CarbonylContact O-C 3.35Å; V197-C562 HydrophobicContact CB-CB 4.26Å; V197-C562 PolarHBondContact N-O 3.23Å; V197-C562 PolarHBondContact O-N 3.44Å
198E92.1Very high69.1Low80 Ų8093.4 Ų93.437%0.37444%0.443SS..EExtended strand (participates in β ladder)trans-132152.8174.868.9160.6-172.900114.2L196 F202 Y560 W561L196-E198 HydrophobicContact CD1-CB 4.35Å; L196-E198 HydrophobicContact CD2-CB 4.5Å; L196-E198 HydrophobicContact CD2-CG 4.33Å; L196-E198 HydrophobicContact CG-CB 4.33Å; E198-F202 WeakPolarHBondContact OE1-CE1 3.1Å; E198-F202 WeakPolarHBondContact OE1-CZ 3.38Å; E198-Y560 WeakPolarHBondContact CA-O 3.35Å; E198-W561 VanDerWaalsContact CB-CD1 3.46Å; E198-W561 HydrophobicContact CB-CG 4.37Å; E198-W561 PolarHBondContact OE2-NE1 3.02Å
199R89.4Confident67.8Low62 Ų6296.1 Ų96.123%0.23446%0.459CS..EExtended strand (participates in β ladder)trans-140.2136.2173.4-177.7-167176.193.9-8.5109S115 S555 N558 T559 Y560S115-R199 VanDerWaalsContact CA-NH1 3.28Å; S115-R199 PolarHBondContact O-NH1 3Å; S115-R199 PolarHBondContact OG-NH1 2.73Å; S115-R199 PolarHBondContact OG-NH2 2.96Å; R199-S555 PolarHBondContact NH2-O 3.39Å; R199-N558 WeakPolarHBondContact CD-O 3.08Å; R199-N558 PolarHBondContact NE-O 2.84Å; R199-T559 CarbonylContact O-C 3.53Å; R199-T559 WeakPolarHBondContact O-CA 3.04Å; R199-T559 WeakPolarHBondContact O-CG2 3.1Å; R199-Y560 HydrophobicContact CB-CD1 4.05Å; R199-Y560 HydrophobicContact CB-CD2 4.02Å; R199-Y560 HydrophobicContact CB-CE1 3.64Å; R199-Y560 HydrophobicContact CB-CE2 3.58Å; R199-Y560 HydrophobicContact CB-CG 4.22Å; R199-Y560 HydrophobicContact CG-CE1 4.1Å; R199-Y560 PolarHBondContact N-O 3.28Å; R199-Y560 PolarHBondContact O-N 3.09Å
200G81.1Confident66.2Low49 Ų4998.9 Ų98.951%0.50549%0.486SS..SBendtrans145.5-152.516800000112
201K62Low64.1Low169 Ų169103.5 Ų103.574%0.73550%0.502SS*.  trans-106.2131167.6-68.4171.5-174.8162.40108.2L203K201-L203 PolarHBondContact O-N 2.93Å
202F52.9Low61.6Low164 Ų164109.7 Ų109.772%0.71954%0.537SS*.  trans-48.3115.2161.4-73.1-78.4000109.3E198 R204E198-F202 WeakPolarHBondContact OE1-CE1 3.1Å; E198-F202 WeakPolarHBondContact OE1-CZ 3.38Å; F202-R204 PolarHBondContact O-N 2.82Å
203L47.2Very low59Low153 Ų153116.3 Ų116.380%0.80157%0.571SS**  trans-68.880.8166-69.7176.3000107.2K201 K205K201-L203 PolarHBondContact O-N 2.93Å; L203-K205 PolarHBondContact O-N 2.97Å
204R37.9Very low56.3Low230 Ų230123.5 Ų123.587%0.86860%0.604SS**  trans-49.3117.7169.7-83.9-170.5168.4-163.8-4.5107.1F202 K206F202-R204 PolarHBondContact O-N 2.82Å; R204-K206 PolarHBondContact O-N 3.43Å
205K37.3Very low53.5Low203 Ų203131.8 Ų131.888%0.88364%0.643SS**  trans-66.977.1-170.5-154.2177.2-170.6178.60110.2L203 E207L203-K205 PolarHBondContact O-N 2.97Å; K205-E207 PolarHBondContact O-N 3.39Å
206K31.3Very low50.8Low155 Ų155134 Ų13467%0.67466%0.662SS**  trans-65.7123.1165.2-174.5-173.5176.7-163.70105.7R204 E208R204-K206 PolarHBondContact O-N 3.43Å; K206-E208 HydrophobicContact CD-CG 3.88Å; K206-E208 WeakPolarHBondContact CD-OE1 3.49Å; K206-E208 VanDerWaalsContact CE-OE1 3.23Å; K206-E208 WeakPolarHBondContact CE-OE1 3.24Å; K206-E208 HydrophobicContact CG-CG 4.02Å; K206-E208 IonicContact NZ-OE1 2.79Å; K206-E208 PolarHBondContact NZ-OE1 2.77Å; K206-E208 PolarHBondContact O-N 2.76Å
207E37.1Very low48.2Very low197 Ų197138 Ų13892%0.92168%0.684SS**  trans-70.381.3177.6-65.1177.3120.800109.6K205K205-E207 PolarHBondContact O-N 3.39Å
208E31.6Very low46Very low140 Ų140143.4 Ų143.465%0.65471%0.708SS**  trans-92.1119.6167-62.1-158.515300108.5K206K206-E208 HydrophobicContact CD-CG 3.88Å; K206-E208 WeakPolarHBondContact CD-OE1 3.49Å; K206-E208 VanDerWaalsContact CE-OE1 3.23Å; K206-E208 WeakPolarHBondContact CE-OE1 3.24Å; K206-E208 HydrophobicContact CG-CG 4.02Å; K206-E208 IonicContact NZ-OE1 2.79Å; K206-E208 PolarHBondContact NZ-OE1 2.77Å; K206-E208 PolarHBondContact O-N 2.76Å
209S33.6Very low44.2Very low108 Ų108143.3 Ų143.376%0.75571%0.709SS**  trans-65.3145.1-170.646.10000112.8K211S209-K211 PolarHBondContact O-N 2.82Å; S209-K211 VanDerWaalsContact O-N 3.17Å
210S36.9Very low42.9Very low121 Ų121144 Ų14485%0.84672%0.722SS**  trans-39.1111.3-169.5-49.60000114.8
211K33.1Very low41.7Very low188 Ų188150.2 Ų150.282%0.81774%0.735SS**  trans-128.6121.3160-70.9-172.8178.4-178.70108.6S209 I213S209-K211 PolarHBondContact O-N 2.82Å; S209-K211 VanDerWaalsContact O-N 3.17Å; K211-I213 PolarHBondContact O-N 2.88Å
212N33.5Very low42.2Very low149 Ų149147.6 Ų147.680%0.79772%0.721SS**  trans-66.8101.7-176.4-70-10.9000110.9Q214N212-Q214 VanDerWaalsContact C-N 3.34Å; N212-Q214 PolarHBondContact O-N 2.99Å
213I35Very low43Very low145 Ų145144.4 Ų144.474%0.74471%0.709SS**  trans-88.380.9162-56179.7000107.1K211 Q215K211-I213 PolarHBondContact O-N 2.88Å; I213-Q215 HydrophobicContact CG2-CG 4.23Å; I213-Q215 PolarHBondContact O-N 3.21Å
214Q35Very low44.2Very low174 Ų174141 Ų14181%0.81369%0.685SS**  trans-85.595166.1-77.5-176.3-2000108.8N212N212-Q214 VanDerWaalsContact C-N 3.34Å; N212-Q214 PolarHBondContact O-N 2.99Å
215Q33.3Very low46Very low178 Ų178131.3 Ų131.383%0.83265%0.652SS**  trans-105.695.6162.4-74.8-175.6-39.100107.9I213I213-Q215 HydrophobicContact CG2-CG 4.23Å; I213-Q215 PolarHBondContact O-N 3.21Å
216S38.2Very low47.9Very low80 Ų80126.6 Ų126.656%0.55963%0.631SS**  trans-89.8146.7173.753.80000110.7H218S216-H218 PolarHBondContact O-N 2.91Å; S216-H218 PolarHBondContact O-ND1 2.91Å
217N38.9Very low50Low134 Ų134123.1 Ų123.172%0.71762%0.617SS**  trans-54.5125.7178.1-68.5-28.2000111.2L219N217-L219 PolarHBondContact O-N 2.96Å
218H48.7Very low51.9Low132 Ų132116 Ų11661%0.61159%0.585SS**  trans-99.989.6-170.5-90.732.1000112S216 R224S216-H218 PolarHBondContact O-N 2.91Å; S216-H218 PolarHBondContact O-ND1 2.91Å; H218-R224 PolarHBondContact CD2-NH2 2.9Å; H218-R224 PolarHBondContact CE1-NH1 3.29Å; H218-R224 VanDerWaalsContact CE1-NH1 3.28Å; H218-R224 PolarHBondContact ND1-NH2 2.96Å; H218-R224 PolarHBondContact NE2-NH1 2.91Å; H218-R224 VanDerWaalsContact NE2-NH1 3.16Å
219L55Low54.2Low78 Ų78109.8 Ų109.841%0.40856%0.557SS.*  trans-53.4144.9154-70.4175.4000109.7N217 R224N217-L219 PolarHBondContact O-N 2.96Å; L219-R224 PolarHBondContact O-NH2 3.05Å
220P60.5Low56.3Low78 Ų78110.7 Ų110.751%0.50655%0.549SS..  trans-42.6141.6172.3-31.134000113.4Y222 E223 R224P220-Y222 PolarHBondContact O-N 2.95Å; P220-E223 HydrophobicContact CB-CG 4.49Å; P220-E223 WeakPolarHBondContact CD-OE2 3.47Å; P220-E223 PolarHBondContact O-N 3.29Å; P220-E223 VanDerWaalsContact O-N 3.09Å; P220-R224 PolarHBondContact O-N 2.89Å
221K56.7Low58.2Low179 Ų179108.1 Ų108.178%0.77852%0.524SS*.Hα-helixtrans-52.1-34.1-175.7-176.7-178.6176.4-175.20113V225K221-V225 WeakPolarHBondContact O-CG2 3.47Å; K221-V225 PolarHBondContact O-N 3.12Å
222Y71.7Confident59.9Low114 Ų114102.5 Ų102.545%0.44751%0.513SS..Hα-helixtrans-68.1-50.1179.1178-120.5000112.8P220 R224 V225 K226 K254P220-Y222 PolarHBondContact O-N 2.95Å; Y222-R224 VanDerWaalsContact C-N 3.34Å; Y222-R224 PolarHBondContact O-N 2.9Å; Y222-V225 PolarHBondContact O-N 3.08Å; Y222-V225 VanDerWaalsContact O-N 3.13Å; Y222-K226 PolarHBondContact O-N 3.09Å; Y222-K254 HydrophobicContact CE2-CB 4.13Å; Y222-K254 HydrophobicContact CE2-CG 3.86Å
223E70.7Confident61.5Low96 Ų96102.7 Ų102.745%0.44950%0.502SS..Hα-helixtrans-63.7-41-178.9-66176.3169.400111.5P220 V225 K226 E227P220-E223 HydrophobicContact CB-CG 4.49Å; P220-E223 WeakPolarHBondContact CD-OE2 3.47Å; P220-E223 PolarHBondContact O-N 3.29Å; P220-E223 VanDerWaalsContact O-N 3.09Å; E223-V225 VanDerWaalsContact C-N 3.26Å; E223-V225 PolarHBondContact O-N 3.44Å; E223-K226 WeakPolarHBondContact O-CB 3.41Å; E223-K226 PolarHBondContact O-N 3.45Å; E223-K226 VanDerWaalsContact O-N 3.09Å; E223-E227 WeakPolarHBondContact O-CB 3.3Å; E223-E227 PolarHBondContact O-N 3.17Å
224R71.8Confident63.3Low82 Ų8297.6 Ų97.631%0.30947%0.474SS..Hα-helixtrans-59.6-35.6174.7-164.2-174.3-48-176.75.5112.8H218 L219 P220 Y222 L228H218-R224 PolarHBondContact CD2-NH2 2.9Å; H218-R224 PolarHBondContact CE1-NH1 3.29Å; H218-R224 VanDerWaalsContact CE1-NH1 3.28Å; H218-R224 PolarHBondContact ND1-NH2 2.96Å; H218-R224 PolarHBondContact NE2-NH1 2.91Å; H218-R224 VanDerWaalsContact NE2-NH1 3.16Å; L219-R224 PolarHBondContact O-NH2 3.05Å; P220-R224 PolarHBondContact O-N 2.89Å; Y222-R224 VanDerWaalsContact C-N 3.34Å; Y222-R224 PolarHBondContact O-N 2.9Å; R224-L228 WeakPolarHBondContact O-CB 3.48Å; R224-L228 WeakPolarHBondContact O-CD1 3.41Å; R224-L228 VanDerWaalsContact O-CG 3.24Å; R224-L228 WeakPolarHBondContact O-CG 3.44Å; R224-L228 PolarHBondContact O-N 2.88Å; R224-L228 VanDerWaalsContact O-N 3.13Å
225V75.1Confident65Low27 Ų2795 Ų9516%0.16446%0.462CS..Hα-helixtrans-73.8-40174.5170.30000110.7K221 Y222 E223 L228 C229 L255 I257K221-V225 WeakPolarHBondContact O-CG2 3.47Å; K221-V225 PolarHBondContact O-N 3.12Å; Y222-V225 PolarHBondContact O-N 3.08Å; Y222-V225 VanDerWaalsContact O-N 3.13Å; E223-V225 VanDerWaalsContact C-N 3.26Å; E223-V225 PolarHBondContact O-N 3.44Å; V225-L228 PolarHBondContact O-N 3.47Å; V225-C229 WeakPolarHBondContact O-CB 3.42Å; V225-C229 PolarHBondContact O-N 3.44Å; V225-C229 PolarHBondContact O-SG 3.47Å; V225-L255 HydrophobicContact CG1-CB 4.2Å; V225-L255 WeakPolarHBondContact CG1-O 3.43Å; V225-I257 HydrophobicContact CG1-CG1 4.06Å
226K77.9Confident66.8Low103 Ų10389.4 Ų89.445%0.44844%0.44SS..Hα-helixtrans-59.3-47.4174.4-170.1178.7-179.4-177.50112Y222 E223 C229 Q230 L255Y222-K226 PolarHBondContact O-N 3.09Å; E223-K226 WeakPolarHBondContact O-CB 3.41Å; E223-K226 PolarHBondContact O-N 3.45Å; E223-K226 VanDerWaalsContact O-N 3.09Å; K226-C229 PolarHBondContact O-N 2.99Å; K226-Q230 WeakPolarHBondContact O-CG 3.36Å; K226-Q230 PolarHBondContact O-N 2.9Å; K226-Q230 VanDerWaalsContact O-N 3.11Å; K226-L255 HydrophobicContact CG-CD1 4.38Å
227E75.9Confident68.5Low82 Ų8287.1 Ų87.138%0.38343%0.426SS..Hα-helixtrans-63.3-40.5176.8-174.4-177.7-157.200112.1E223 Q230E223-E227 WeakPolarHBondContact O-CB 3.3Å; E223-E227 PolarHBondContact O-N 3.17Å; E227-Q230 PolarHBondContact O-N 3.26Å
228L76.9Confident70Confident48 Ų4883.5 Ų83.525%0.25141%0.41SS..Hα-helixtrans-63.9-45.3173.4-76.2167.4000111.5R224 V225 Q230 Q231 Y234 I257R224-L228 WeakPolarHBondContact O-CB 3.48Å; R224-L228 WeakPolarHBondContact O-CD1 3.41Å; R224-L228 VanDerWaalsContact O-CG 3.24Å; R224-L228 WeakPolarHBondContact O-CG 3.44Å; R224-L228 PolarHBondContact O-N 2.88Å; R224-L228 VanDerWaalsContact O-N 3.13Å; V225-L228 PolarHBondContact O-N 3.47Å; L228-Q230 PolarHBondContact O-N 2.9Å; L228-Q231 WeakPolarHBondContact O-CB 3.48Å; L228-Q231 PolarHBondContact O-N 3.3Å; L228-Y234 HydrophobicContact CD2-CE2 4.09Å; L228-Y234 VanDerWaalsContact O-CD2 3.28Å; L228-Y234 WeakPolarHBondContact O-CD2 3.23Å; L228-I257 HydrophobicContact CB-CD1 3.87Å; L228-I257 HydrophobicContact CD1-CD1 3.67Å; L228-I257 HydrophobicContact CG-CD1 4.4Å
229C78.9Confident70.9Confident10 Ų1084.6 Ų84.67%0.06842%0.416CS..Hα-helixtrans-69.6-9.2178.5-63.10000114.6V225 K226 Q231 Q235 C247 L255V225-C229 WeakPolarHBondContact O-CB 3.42Å; V225-C229 PolarHBondContact O-N 3.44Å; V225-C229 PolarHBondContact O-SG 3.47Å; K226-C229 PolarHBondContact O-N 2.99Å; C229-Q231 VanDerWaalsContact C-N 3.31Å; C229-Q235 WeakPolarHBondContact O-CG 3.19Å; C229-Q235 PolarHBondContact O-NE2 3.33Å; C229-Q235 VanDerWaalsContact O-NE2 3.07Å; C229-C247 WeakPolarHBondContact CA-SG 3.35Å; C229-C247 HydrophobicContact CB-CB 3.68Å; C229-C247 WeakPolarHBondContact CB-SG 3.23Å; C229-C247 WeakPolarHBondContact SG-CB 3.28Å; C229-C247 CovalentContact SG-SG 2.03Å; C229-C247 PolarHBondContact SG-SG 3.15Å; C229-L255 HydrophobicContact CB-CD1 3.96Å
230Q78.7Confident71.3Confident126 Ų12686.3 Ų86.359%0.58942%0.422SS*.THydrogen-bonded Turntrans-80.8-9.8169.3-75.4170-30.900113.1K226 E227 L228 Q235K226-Q230 WeakPolarHBondContact O-CG 3.36Å; K226-Q230 PolarHBondContact O-N 2.9Å; K226-Q230 VanDerWaalsContact O-N 3.11Å; E227-Q230 PolarHBondContact O-N 3.26Å; L228-Q230 PolarHBondContact O-N 2.9Å; Q230-Q235 PolarHBondContact O-NE2 2.84Å
231Q75.8Confident71.4Confident68 Ų6888.8 Ų88.832%0.31844%0.438SS..SBendtrans-86.5124.7177.5-54.91748.300110.1L228 C229 R233 Y234L228-Q231 WeakPolarHBondContact O-CB 3.48Å; L228-Q231 PolarHBondContact O-N 3.3Å; C229-Q231 VanDerWaalsContact C-N 3.31Å; Q231-R233 HydrophobicContact CB-CG 4.2Å; Q231-R233 PolarHBondContact O-N 2.78Å; Q231-R233 VanDerWaalsContact OE1-CZ 3.29Å; Q231-Y234 HydrophobicContact CB-CD2 4.16Å; Q231-Y234 PolarHBondContact O-N 3.01Å
232A70Confident71.9Confident70 Ų7083.6 Ų83.658%0.57944%0.435SS*.G310 helixtrans-46.8-37.6-174.800000114.6Y234 Q235A232-Y234 PolarHBondContact O-N 2.67Å; A232-Q235 PolarHBondContact O-N 2.91Å
233R67.3Low71.8Confident153 Ų15379.7 Ų79.758%0.57742%0.421SS*.G310 helixtrans-60.6-8177.168.4176.8176.3160.70.1116.4Q231Q231-R233 HydrophobicContact CB-CG 4.2Å; Q231-R233 PolarHBondContact O-N 2.78Å; Q231-R233 VanDerWaalsContact OE1-CZ 3.29Å
234Y72.8Confident72Confident38 Ų3882.1 Ų82.115%0.14943%0.43CS..G310 helixtrans-121.5-3.7175-58-63.2000113.1L228 Q231 A232 W245 C247L228-Y234 HydrophobicContact CD2-CE2 4.09Å; L228-Y234 VanDerWaalsContact O-CD2 3.28Å; L228-Y234 WeakPolarHBondContact O-CD2 3.23Å; Q231-Y234 HydrophobicContact CB-CD2 4.16Å; Q231-Y234 PolarHBondContact O-N 3.01Å; A232-Y234 PolarHBondContact O-N 2.67Å; Y234-W245 HydrophobicContact CD1-CB 3.93Å; Y234-W245 HydrophobicContact CE1-CB 3.9Å; Y234-W245 HydrophobicContact CE1-CG 4.41Å; Y234-C247 PolarHBondContact O-N 2.96Å
235Q71.1Confident72.4Confident118 Ų11883.9 Ų83.955%0.55144%0.437SS*.THydrogen-bonded Turntrans-87.3-30.1179.4-68.7176.5-2100112.3C229 Q230 A232C229-Q235 WeakPolarHBondContact O-CG 3.19Å; C229-Q235 PolarHBondContact O-NE2 3.33Å; C229-Q235 VanDerWaalsContact O-NE2 3.07Å; Q230-Q235 PolarHBondContact O-NE2 2.84Å; A232-Q235 PolarHBondContact O-N 2.91Å
236T70.3Confident72.8Confident61 Ų6184.8 Ų84.837%0.37444%0.439SS..SBendtrans-65.2144.2172.151.30000111Q243T236-Q243 PolarHBondContact O-NE2 3.12Å; T236-Q243 PolarHBondContact OG1-NE2 3.25Å; T236-Q243 PolarHBondContact OG1-OE1 3.26Å
237A73.7Confident73.3Confident32 Ų3280.8 Ų80.826%0.26442%0.424SS..  trans-59.4161.1165.100000111E239 Q243A237-E239 HydrophobicContact CB-CG 4.05Å; A237-E239 WeakPolarHBondContact CB-OE1 3.44Å; A237-E239 PolarHBondContact O-N 3.19Å; A237-Q243 PolarHBondContact O-OE1 2.72Å
238C71.1Confident73.5Confident58 Ų5880.6 Ų80.639%0.39243%0.425SS..THydrogen-bonded Turntrans-67.250-179.4-720000114.7Q246 C260C238-Q246 VanDerWaalsContact SG-CB 3.52Å; C238-Q246 PolarHBondContact SG-OE1 2.87Å; C238-C260 HydrophobicContact CB-CB 3.67Å; C238-C260 WeakPolarHBondContact CB-SG 3.4Å; C238-C260 WeakPolarHBondContact SG-CA 3.46Å; C238-C260 WeakPolarHBondContact SG-CB 3.42Å; C238-C260 CovalentContact SG-SG 2.04Å; C238-C260 PolarHBondContact SG-SG 2.75Å
239E66.5Low73.7Confident155 Ų15584 Ų8472%0.72444%0.44SS*.THydrogen-bonded Turntrans-107.9-25.4-172.9-65.3166.3-174.100112.1A237A237-E239 HydrophobicContact CB-CG 4.05Å; A237-E239 WeakPolarHBondContact CB-OE1 3.44Å; A237-E239 PolarHBondContact O-N 3.19Å
240Q64.8Low73.6Confident115 Ų11585.6 Ų85.654%0.53745%0.447SS..SBendtrans-78.1131.3-176.7-64.6-62.8-35.500111.7G242 Q243Q240-G242 PolarHBondContact O-N 3.08Å; Q240-G242 VanDerWaalsContact O-N 3.15Å; Q240-Q243 HydrophobicContact CB-CB 4.16Å; Q240-Q243 VanDerWaalsContact O-CB 3.27Å; Q240-Q243 WeakPolarHBondContact O-CB 3.27Å; Q240-Q243 PolarHBondContact O-N 3.16Å
241P62.1Low73.3Confident129 Ų12987 Ų8784%0.83847%0.465SS*.THydrogen-bonded Turntrans-62.9119.3-177.224.7-33.3000111.1
242G66.1Low73.2Confident70 Ų7087.9 Ų87.972%0.72248%0.478SS*.THydrogen-bonded Turntrans93-3.1-176.100000115.3Q240 K244Q240-G242 PolarHBondContact O-N 3.08Å; Q240-G242 VanDerWaalsContact O-N 3.15Å; G242-K244 PolarHBondContact O-N 2.89Å
243Q70.3Confident73.2Confident32 Ų3286.3 Ų86.315%0.1547%0.469CS..  trans-65.5122.8171.8-173.4175.3-19.600110.4T236 A237 Q240 W245 C260T236-Q243 PolarHBondContact O-NE2 3.12Å; T236-Q243 PolarHBondContact OG1-NE2 3.25Å; T236-Q243 PolarHBondContact OG1-OE1 3.26Å; A237-Q243 PolarHBondContact O-OE1 2.72Å; Q240-Q243 HydrophobicContact CB-CB 4.16Å; Q240-Q243 VanDerWaalsContact O-CB 3.27Å; Q240-Q243 WeakPolarHBondContact O-CB 3.27Å; Q240-Q243 PolarHBondContact O-N 3.16Å; Q243-W245 WeakPolarHBondContact CG-O 3.05Å; Q243-W245 PolarHBondContact NE2-O 2.99Å; Q243-C260 WeakPolarHBondContact O-CB 3.41Å
244K74.3Confident73.7Confident148 Ų14884.2 Ų84.264%0.64346%0.464SS*.  trans-100.7-16.9-175.4-66.8179.9-176.2177.40113.9G242 K259 C260G242-K244 PolarHBondContact O-N 2.89Å; K244-K259 WeakPolarHBondContact O-CA 3.03Å; K244-K259 WeakPolarHBondContact O-CG 3.41Å; K244-C260 PolarHBondContact O-N 2.9Å
245W80.3Confident74Confident119 Ų11985 Ų8545%0.45147%0.47SS..EExtended strand (participates in β ladder)trans-148.1151.8-174.4-51.291.9000111.7Y234 Q243 I257 H258 K259Y234-W245 HydrophobicContact CD1-CB 3.93Å; Y234-W245 HydrophobicContact CE1-CB 3.9Å; Y234-W245 HydrophobicContact CE1-CG 4.41Å; Q243-W245 WeakPolarHBondContact CG-O 3.05Å; Q243-W245 PolarHBondContact NE2-O 2.99Å; W245-I257 HydrophobicContact CB-CG2 3.83Å; W245-I257 HydrophobicContact CD2-CG2 4.37Å; W245-I257 HydrophobicContact CE3-CG2 4.02Å; W245-I257 HydrophobicContact CG-CG2 4.32Å; W245-H258 CarbonylContact C-O 3.59Å; W245-H258 WeakPolarHBondContact CA-O 3.39Å; W245-K259 HydrophobicContact CD2-CB 4.47Å; W245-K259 HydrophobicContact CD2-CG 4.5Å; W245-K259 HydrophobicContact CE3-CB 3.78Å; W245-K259 HydrophobicContact CE3-CG 4.26Å; W245-K259 HydrophobicContact CH2-CB 4.16Å; W245-K259 HydrophobicContact CH2-CG 4.25Å; W245-K259 HydrophobicContact CZ2-CG 4.49Å; W245-K259 HydrophobicContact CZ3-CB 3.61Å; W245-K259 HydrophobicContact CZ3-CG 4.14Å
246Q84.1Confident74.3Confident46 Ų4685.8 Ų85.822%0.21547%0.469CS..EExtended strand (participates in β ladder)trans-138149.3175.6167.8-179.4-4.100109C238 I248 H258C238-Q246 VanDerWaalsContact SG-CB 3.52Å; C238-Q246 PolarHBondContact SG-OE1 2.87Å; Q246-I248 HydrophobicContact CG-CG1 4.27Å; Q246-H258 PolarHBondContact N-O 2.86Å; Q246-H258 PolarHBondContact O-N 3.01Å
247C87.8Confident74.9Confident19 Ų1985.4 Ų85.413%0.12846%0.464CS..EExtended strand (participates in β ladder)trans-89.5138.3167.8-72.20000112.4C229 Y234 R256C229-C247 WeakPolarHBondContact CA-SG 3.35Å; C229-C247 HydrophobicContact CB-CB 3.68Å; C229-C247 WeakPolarHBondContact CB-SG 3.23Å; C229-C247 WeakPolarHBondContact SG-CB 3.28Å; C229-C247 CovalentContact SG-SG 2.03Å; C229-C247 PolarHBondContact SG-SG 3.15Å; Y234-C247 PolarHBondContact O-N 2.96Å; C247-R256 WeakPolarHBondContact CA-O 3.39Å
248I80.5Confident75.2Confident78 Ų7888.1 Ų88.140%0.447%0.471SS..EExtended strand (participates in β ladder)trans-134.7144.5177.5-54.6179.2000107.5Q246 L255 R256 H258Q246-I248 HydrophobicContact CG-CG1 4.27Å; I248-L255 CarbonylContact O-C 3.48Å; I248-L255 WeakPolarHBondContact O-CA 3.38Å; I248-R256 PolarHBondContact N-O 3.34Å; I248-R256 PolarHBondContact O-N 2.92Å; I248-H258 HydrophobicContact CD1-CB 4.05Å
249E81.9Confident75.5Confident120 Ų12091.1 Ų91.156%0.56148%0.477SS*.EExtended strand (participates in β ladder)trans-94.9129175.2-169.3159.7-156.200111.1G253 L255E249-G253 VanDerWaalsContact OE1-CA 3.25Å; E249-G253 WeakPolarHBondContact OE1-CA 3.37Å; E249-L255 HydrophobicContact CB-CD2 4.16Å
250D75.6Confident76Confident42 Ų4284.4 Ų84.423%0.22545%0.447CS..EExtended strand (participates in β ladder)trans-62.7157.9170.7-73.7-28.4000110.9S252 G253 K254 R256D250-S252 PolarHBondContact O-N 2.91Å; D250-G253 PolarHBondContact O-N 2.04Å; D250-K254 HydrophobicContact CB-CB 4.48Å; D250-K254 WeakPolarHBondContact CB-O 3.2Å; D250-K254 PolarHBondContact N-O 2.96Å; D250-R256 WeakPolarHBondContact OD1-CD 3.49Å; D250-R256 IonicContact OD1-CZ 2.79Å; D250-R256 VanDerWaalsContact OD1-CZ 3.3Å; D250-R256 IonicContact OD1-NE 3.57Å; D250-R256 PolarHBondContact OD1-NE 3.2Å; D250-R256 IonicContact OD1-NH2 2.76Å; D250-R256 IonicContact OD2-CZ 3.39Å; D250-R256 IonicContact OD2-NE 3.95Å; D250-R256 PolarHBondContact OD2-NE 3.18Å; D250-R256 IonicContact OD2-NH2 3.16Å; D250-R256 PolarHBondContact OD2-NH2 3Å
251T73.4Confident76.1Confident156 Ų15688.7 Ų88.796%0.95746%0.464SS*.THydrogen-bonded Turntrans-57.40.8166.555.80000115.2
252S72.7Confident75.8Confident86 Ų8684.9 Ų84.960%0.60145%0.448SS*.THydrogen-bonded Turntrans-113.418175.9-51.90000113.5D250D250-S252 PolarHBondContact O-N 2.91Å
253G71.1Confident74.9Confident38 Ų3888.3 Ų88.339%0.39246%0.458SS..THydrogen-bonded Turntrans67.139.417800000113.4E249 D250E249-G253 VanDerWaalsContact OE1-CA 3.25Å; E249-G253 WeakPolarHBondContact OE1-CA 3.37Å; D250-G253 PolarHBondContact O-N 2.04Å
254K76.6Confident73.5Confident109 Ų10991.6 Ų91.647%0.47448%0.484SS..EExtended strand (participates in β ladder)trans-134.2118.3-175.3-70.3-179.6-176.7171.10111.4Y222 D250Y222-K254 HydrophobicContact CE2-CB 4.13Å; Y222-K254 HydrophobicContact CE2-CG 3.86Å; D250-K254 HydrophobicContact CB-CB 4.48Å; D250-K254 WeakPolarHBondContact CB-O 3.2Å; D250-K254 PolarHBondContact N-O 2.96Å
255L79.8Confident71.9Confident53 Ų5391 Ų9128%0.27749%0.488SS..EExtended strand (participates in β ladder)trans-64.5139.9176.7-66.1165.9000112.1V225 K226 C229 I248 E249V225-L255 HydrophobicContact CG1-CB 4.2Å; V225-L255 WeakPolarHBondContact CG1-O 3.43Å; K226-L255 HydrophobicContact CG-CD1 4.38Å; C229-L255 HydrophobicContact CB-CD1 3.96Å; I248-L255 CarbonylContact O-C 3.48Å; I248-L255 WeakPolarHBondContact O-CA 3.38Å; E249-L255 HydrophobicContact CB-CD2 4.16Å
256R78.1Confident69.9Low136 Ų13693.1 Ų93.151%0.51351%0.507SS..EExtended strand (participates in β ladder)trans-136.5150.9172-64.8-165.7-173.5178.816.6110.8C247 I248 D250C247-R256 WeakPolarHBondContact CA-O 3.39Å; I248-R256 PolarHBondContact N-O 3.34Å; I248-R256 PolarHBondContact O-N 2.92Å; D250-R256 WeakPolarHBondContact OD1-CD 3.49Å; D250-R256 IonicContact OD1-CZ 2.79Å; D250-R256 VanDerWaalsContact OD1-CZ 3.3Å; D250-R256 IonicContact OD1-NE 3.57Å; D250-R256 PolarHBondContact OD1-NE 3.2Å; D250-R256 IonicContact OD1-NH2 2.76Å; D250-R256 IonicContact OD2-CZ 3.39Å; D250-R256 IonicContact OD2-NE 3.95Å; D250-R256 PolarHBondContact OD2-NE 3.18Å; D250-R256 IonicContact OD2-NH2 3.16Å; D250-R256 PolarHBondContact OD2-NH2 3Å
257I83Confident67.8Low53 Ų5398.9 Ų98.927%0.27254%0.539SS..EExtended strand (participates in β ladder)trans-98.1120.3175.8-48.5179.9000109V225 L228 W245V225-I257 HydrophobicContact CG1-CG1 4.06Å; L228-I257 HydrophobicContact CB-CD1 3.87Å; L228-I257 HydrophobicContact CD1-CD1 3.67Å; L228-I257 HydrophobicContact CG-CD1 4.4Å; W245-I257 HydrophobicContact CB-CG2 3.83Å; W245-I257 HydrophobicContact CD2-CG2 4.37Å; W245-I257 HydrophobicContact CE3-CG2 4.02Å; W245-I257 HydrophobicContact CG-CG2 4.32Å
258H78.1Confident65.1Low89 Ų89104.7 Ų104.741%0.41257%0.573SS.*EExtended strand (participates in β ladder)trans-108.4145.7177.9-78.8-116.9000110.8W245 Q246 I248W245-H258 CarbonylContact C-O 3.59Å; W245-H258 WeakPolarHBondContact CA-O 3.39Å; Q246-H258 PolarHBondContact N-O 2.86Å; Q246-H258 PolarHBondContact O-N 3.01Å; I248-H258 HydrophobicContact CD1-CB 4.05Å
259K77.8Confident62.9Low121 Ų121107.5 Ų107.553%0.52659%0.594SS.*EExtended strand (participates in β ladder)trans-79.6129.6175.8-166.5-160.5170.6-162.60109.6K244 W245 D265K244-K259 WeakPolarHBondContact O-CA 3.03Å; K244-K259 WeakPolarHBondContact O-CG 3.41Å; W245-K259 HydrophobicContact CD2-CB 4.47Å; W245-K259 HydrophobicContact CD2-CG 4.5Å; W245-K259 HydrophobicContact CE3-CB 3.78Å; W245-K259 HydrophobicContact CE3-CG 4.26Å; W245-K259 HydrophobicContact CH2-CB 4.16Å; W245-K259 HydrophobicContact CH2-CG 4.25Å; W245-K259 HydrophobicContact CZ2-CG 4.49Å; W245-K259 HydrophobicContact CZ3-CB 3.61Å; W245-K259 HydrophobicContact CZ3-CG 4.14Å; K259-D265 IonicContact NZ-OD2 2.66Å
260C77.6Confident60.6Low13 Ų13112 Ų1129%0.08861%0.606CS.*  trans-64.2135.1170.2-59.50000110.3C238 Q243 K244C238-C260 HydrophobicContact CB-CB 3.67Å; C238-C260 WeakPolarHBondContact CB-SG 3.4Å; C238-C260 WeakPolarHBondContact SG-CA 3.46Å; C238-C260 WeakPolarHBondContact SG-CB 3.42Å; C238-C260 CovalentContact SG-SG 2.04Å; C238-C260 PolarHBondContact SG-SG 2.75Å; Q243-C260 WeakPolarHBondContact O-CB 3.41Å; K244-C260 PolarHBondContact O-N 2.9Å
261K67.4Low58.5Low206 Ų206117.9 Ų117.990%0.89663%0.632SS**  trans-99.7100.2176-70.9-175.4178.6-179.60109.7
262G54.5Low56.4Low49 Ų49116.3 Ų116.351%0.50563%0.627SS.*  trans-81.9152.8171.400000112.3S264G262-S264 PolarHBondContact O-N 3.25Å
263P48.6Very low54.4Low142 Ų142118.1 Ų118.192%0.92264%0.635SS**THydrogen-bonded Turntrans-80.346.1-174.735.8-38.5000113.1
264S41.6Very low52.4Low101 Ų101127 Ų12771%0.70666%0.657SS**THydrogen-bonded Turntrans-134.4-16.1-169.1-47.60000115.6G262 L266G262-S264 PolarHBondContact O-N 3.25Å; S264-L266 VanDerWaalsContact C-N 3.29Å; S264-L266 PolarHBondContact O-N 2.81Å; S264-L266 VanDerWaalsContact O-N 3.11Å
265D39.1Very low50.1Low135 Ų135129.5 Ų129.572%0.72268%0.675SS**THydrogen-bonded Turntrans-85.642.4-175.4-79.7-19.7000113.1K259K259-D265 IonicContact NZ-OD2 2.66Å
266L39.7Very low47.7Very low164 Ų164133.8 Ų133.886%0.85970%0.697SS**THydrogen-bonded Turntrans-129.7-12.7-176.9-91.4174.6000117.9S264S264-L266 VanDerWaalsContact C-N 3.29Å; S264-L266 PolarHBondContact O-N 2.81Å; S264-L266 VanDerWaalsContact O-N 3.11Å
267L39.1Very low45.4Very low167 Ų167138.7 Ų138.787%0.87472%0.718SS**  trans-140.767.8-174.7-74.7177000115.3
268T31.9Very low42.8Very low140 Ų140140.5 Ų140.586%0.85974%0.74SS**  trans-145.5109150.150.20000111.6
269V33.2Very low40.6Very low138 Ų138147.7 Ų147.784%0.83676%0.764SS**  trans-121.2147.5163.9-179.90000106.9
270R33.5Very low38.2Very low215 Ų215145.2 Ų145.281%0.81177%0.773SS**  trans76.7151.6-170-50.4179180178.80.4112.5
271Q31.5Very low35.9Very low165 Ų165153.1 Ų153.177%0.77181%0.806SS**  cis-150.3150-2.5-130150.7-19.900109.2
272S29.1Very low34.2Very low122 Ų122151 Ų15185%0.85380%0.799SS**  trans-105.5114.5174.7-176.10000110.3
273T30.5Very low32.9Very low125 Ų125156 Ų15677%0.76782%0.815SS**  trans-100.3128.6177.542.80000110.9
274R30.3Very low32.2Very low225 Ų225157.8 Ų157.885%0.84981%0.808SS**  trans-86.1139.2166-68.2174.2172.6168.2-3.7108.5
275N28.3Very low31.8Very low161 Ų161159.8 Ų159.886%0.86181%0.811SS**  trans-111.7138.6161.4-84.6-10.7000110.6
276L30Very low31.6Very low142 Ų142161.6 Ų161.674%0.74381%0.812SS**  trans-142.1104.5-176.4-86.9169.3000109.6
277Y28.9Very low31.1Very low239 Ų239162 Ų16294%0.93781%0.81SS**  trans-161.7162161.3-77-70.8000108
278A28.9Very low30.5Very low91 Ų91159.9 Ų159.975%0.75281%0.807SS**  cis-170.8173.8-40.100000106.8
279R32Very low30.5Very low240 Ų240158.8 Ų158.891%0.90681%0.805SS**  trans-85.6146.7-175.9-71.7176.9172.8162.6-4.3113.7
280G26.2Very low30.3Very low70 Ų70157.6 Ų157.672%0.72280%0.802SS**  trans-129.4166154.500000109.9
281F29.4Very low30Very low178 Ų178158 Ų15878%0.78180%0.803SS**  trans-146.9141.3-168.6-130-106.2000112.5
282H31.5Very low29.9Very low161 Ų161157.3 Ų157.375%0.74580%0.8SS**  trans24.1139.9165.9-71.9-50.6000123.1
283D27.7Very low30.1Very low156 Ų156157 Ų15783%0.83480%0.798SS**  -138.7-175.9121.9-148.3-14.6000111.6
284K34.7Very low30.3Very low179 Ų179154.6 Ų154.678%0.77880%0.798SS**  trans-135.3150.1-169.1-55171.1-177.31690114.5
285D33.2Very low30.5Very low142 Ų142155.4 Ų155.476%0.75980%0.803SS**  trans-153136.1137.8-96.2-41.3000107
286K34.5Very low31.2Very low173 Ų173158.8 Ų158.875%0.75280%0.803SS**  61.6129.976.6-73-168.9175.3-173.90113.6
287E27.7Very low31.9Very low174 Ų174154.2 Ų154.281%0.81379%0.786SS**  cis-151.1180-2.1-162.3141.8-158.700110.9
288C28.5Very low33Very low121 Ų121145.2 Ų145.282%0.81876%0.759SS**  trans-101.2158.8-166.1-68.50000115.5
289S30.7Very low34Very low117 Ų117152.3 Ų152.382%0.81877%0.766SS**  trans151.7156.2140.4-175.30000112.3
290C28.8Very low34.6Very low113 Ų113144.9 Ų144.976%0.76475%0.75SS**  -172.3112.7-56.8-1080000110.4
291R26.7Very low35.7Very low225 Ų225146.7 Ų146.785%0.84974%0.74SS**  trans177.6148.5156.7-108.1-175.6152161-4.1109.8
292E29.4Very low36.9Very low149 Ų149145.4 Ų145.470%0.69673%0.73SS**  cis-145.7144.6-20.8-146.8169.6-109.700105.8
293S34.2Very low37.9Very low116 Ų116145.5 Ų145.581%0.81173%0.728SS**  trans-148.7122.5-173.7-77.20000113
294G34.2Very low39.1Very low75 Ų75141.5 Ų141.577%0.77371%0.713SS**  trans-62.1132-168.900000114.8R296G294-R296 PolarHBondContact O-N 2.88Å; G294-R296 VanDerWaalsContact O-N 3.08Å
295Y35.9Very low39.7Very low241 Ų241139.2 Ų139.295%0.94571%0.705SS**  trans-54.2108.7178.5-85.7-102.1000112.9A297Y295-A297 PolarHBondContact O-N 2.9Å
296R41.6Very low40.5Very low232 Ų232142.4 Ų142.488%0.87571%0.706SS**  trans-85.195.2165.4-79.3-174.2169.2-176.2-1.8110.2G294G294-R296 PolarHBondContact O-N 2.88Å; G294-R296 VanDerWaalsContact O-N 3.08Å
297A45.8Very low41.3Very low46 Ų46141.5 Ų141.538%0.3871%0.705SS.*  trans-48.5139.8177.400000113.3Y295 Q301 R302Y295-A297 PolarHBondContact O-N 2.9Å; A297-Q301 HydrophobicContact CB-CB 4.39Å; A297-R302 PolarHBondContact O-NE 2.94Å
298S51.8Low42Very low51 Ų51141 Ų14136%0.35770%0.7SS.*  trans-72.7166.9-164.784.90000113.8S300 Q301 R302S298-S300 PolarHBondContact O-N 3Å; S298-S300 VanDerWaalsContact O-N 3.15Å; S298-S300 PolarHBondContact OG-OG 2.9Å; S298-Q301 PolarHBondContact O-N 3.11Å; S298-R302 PolarHBondContact O-N 3.03Å; S298-R302 VanDerWaalsContact O-N 3.08Å
299R48.3Very low42.8Very low239 Ų239141.9 Ų141.990%0.90270%0.696SS**THydrogen-bonded Turntrans-65.4-16.3-177.8-153.7175.1-172.5177.62.9113.6
300S45.5Very low43.5Very low84 Ų84146.5 Ų146.559%0.58770%0.696SS**THydrogen-bonded Turntrans-85.9-43.7170.952.70000112.4S298 R302 K303 S304S298-S300 PolarHBondContact O-N 3Å; S298-S300 VanDerWaalsContact O-N 3.15Å; S298-S300 PolarHBondContact OG-OG 2.9Å; S300-R302 VanDerWaalsContact C-N 3.33Å; S300-R302 PolarHBondContact O-N 2.03Å; S300-K303 WeakPolarHBondContact O-CA 3.47Å; S300-K303 WeakPolarHBondContact O-CB 3.32Å; S300-K303 PolarHBondContact O-N 3.02Å; S300-S304 PolarHBondContact O-N 3.11Å
301Q49.7Very low44.5Very low108 Ų108148 Ų14851%0.50570%0.696SS.*Hα-helixtrans-59.7-40.6176.3-72.3171.7-48.400112.2A297 S298 K303 S304 Q305A297-Q301 HydrophobicContact CB-CB 4.39Å; S298-Q301 PolarHBondContact O-N 3.11Å; Q301-K303 PolarHBondContact O-N 2.81Å; Q301-K303 VanDerWaalsContact O-N 3.08Å; Q301-S304 PolarHBondContact O-N 3.47Å; Q301-S304 PolarHBondContact O-OG 2.92Å; Q301-S304 VanDerWaalsContact O-OG 3.07Å; Q301-Q305 PolarHBondContact O-N 2.94Å; Q301-Q305 VanDerWaalsContact O-N 3.15Å
302R55.1Low45.1Very low152 Ų152145.9 Ų145.957%0.57470%0.696SS**Hα-helixtrans-62.7-14173.2-68.4-177.5-179.4-155-7.4114A297 S298 S300A297-R302 PolarHBondContact O-NE 2.94Å; S298-R302 PolarHBondContact O-N 3.03Å; S298-R302 VanDerWaalsContact O-N 3.08Å; S300-R302 VanDerWaalsContact C-N 3.33Å; S300-R302 PolarHBondContact O-N 2.03Å
303K52.4Low46.1Very low162 Ų162142.8 Ų142.870%0.70470%0.704SS**Hα-helixtrans-90.9-43.4179-131.1-176.5-178.4-168.40111.9S300 Q301 R306 Q307S300-K303 WeakPolarHBondContact O-CA 3.47Å; S300-K303 WeakPolarHBondContact O-CB 3.32Å; S300-K303 PolarHBondContact O-N 3.02Å; Q301-K303 PolarHBondContact O-N 2.81Å; Q301-K303 VanDerWaalsContact O-N 3.08Å; K303-R306 PolarHBondContact O-N 2.9Å; K303-Q307 PolarHBondContact O-N 2.9Å
304S51.8Low46.3Very low73 Ų73142.7 Ų142.751%0.5170%0.698SS.*Hα-helixtrans-66.4-40.5174.752.40000112.2S300 Q301 R306 Q307 F308S300-S304 PolarHBondContact O-N 3.11Å; Q301-S304 PolarHBondContact O-N 3.47Å; Q301-S304 PolarHBondContact O-OG 2.92Å; Q301-S304 VanDerWaalsContact O-OG 3.07Å; S304-R306 VanDerWaalsContact C-N 3.28Å; S304-R306 PolarHBondContact O-N 3.49Å; S304-Q307 WeakPolarHBondContact O-CA 3.21Å; S304-Q307 WeakPolarHBondContact O-CB 3.32Å; S304-Q307 PolarHBondContact O-N 3.31Å; S304-F308 PolarHBondContact O-N 3.26Å; S304-F308 VanDerWaalsContact O-N 3.07Å
305Q48.7Very low46.6Very low130 Ų130145.6 Ų145.661%0.60770%0.703SS**Hα-helixtrans-61-35178.1-162.4177.224.600112.7Q301 Q307 L309Q301-Q305 PolarHBondContact O-N 2.94Å; Q301-Q305 VanDerWaalsContact O-N 3.15Å; Q305-Q307 VanDerWaalsContact C-N 3.27Å; Q305-Q307 PolarHBondContact O-N 3.34Å; Q305-L309 WeakPolarHBondContact O-CG 3.18Å; Q305-L309 PolarHBondContact O-N 2.86Å
306R49.9Very low46.6Very low210 Ų210142.9 Ų142.979%0.79270%0.697SS**Hα-helixtrans-71.2-17.6172.4-86.3-169.9169.1-148.6-3114.3K303 S304K303-R306 PolarHBondContact O-N 2.9Å; S304-R306 VanDerWaalsContact C-N 3.28Å; S304-R306 PolarHBondContact O-N 3.49Å
307Q49.6Very low46.3Very low153 Ų153141.8 Ų141.872%0.71569%0.694SS**Hα-helixtrans-89.2-33.5178.7-158.6162.7-9.400111K303 S304 Q305K303-Q307 PolarHBondContact O-N 2.9Å; S304-Q307 WeakPolarHBondContact O-CA 3.21Å; S304-Q307 WeakPolarHBondContact O-CB 3.32Å; S304-Q307 PolarHBondContact O-N 3.31Å; Q305-Q307 VanDerWaalsContact C-N 3.27Å; Q305-Q307 PolarHBondContact O-N 3.34Å
308F44.2Very low45.8Very low164 Ų164147.9 Ų147.972%0.71971%0.712SS**Hα-helixtrans-66.6-46.7172.7-169.8-104.8000112.7S304 R310 N311S304-F308 PolarHBondContact O-N 3.26Å; S304-F308 VanDerWaalsContact O-N 3.07Å; F308-R310 PolarHBondContact O-N 2.91Å; F308-N311 PolarHBondContact O-N 3.12Å
309L44.8Very low45Very low140 Ų140149.4 Ų149.473%0.73372%0.721SS**THydrogen-bonded Turntrans-66.811.2179.5-70.7171.6000115.3Q305Q305-L309 WeakPolarHBondContact O-CG 3.18Å; Q305-L309 PolarHBondContact O-N 2.86Å
310R46.1Very low44.2Very low214 Ų214149.2 Ų149.281%0.80872%0.72SS**THydrogen-bonded Turntrans-101.4-14.7177.6-147.5178.9-170.7-154.30.9113.7F308F308-R310 PolarHBondContact O-N 2.91Å
311N48.9Very low43.6Very low143 Ų143154 Ų15477%0.76573%0.731SS**  trans-120.261.4-173.7-73.917000112.6F308F308-N311 PolarHBondContact O-N 3.12Å
312Q38.4Very low42.8Very low182 Ų182154.9 Ų154.985%0.8574%0.743SS**  trans-133.3129.6154.3-75.4-168.5-15.300108.9
313G50.1Low41.9Very low84 Ų84156 Ų15687%0.86675%0.754SS**  trans-89.5117.9-168.600000113.2
314T38.6Very low41.1Very low114 Ų114155 Ų15570%0.69976%0.762SS**  trans-137.5137.5154.643.30000108.8K316T314-K316 PolarHBondContact O-N 2.99Å
315P41.6Very low40.3Very low135 Ų135162.8 Ų162.888%0.87778%0.78SS**  trans-79.185.5-169.831.3-35.5000111.8Y317P315-Y317 PolarHBondContact O-N 3.16Å
316K36.1Very low39.8Very low185 Ų185165.6 Ų165.680%0.80479%0.793SS**  trans-71.3101.9170.4-75.8-166.9173.4-173.30111T314T314-K316 PolarHBondContact O-N 2.99Å
317Y35.5Very low39Very low208 Ų208162.6 Ų162.682%0.81680%0.798SS**  trans-42.9134.6166.7179.7-91.4000111.1P315P315-Y317 PolarHBondContact O-N 3.16Å
318K35.1Very low38.4Very low175 Ų175166 Ų16676%0.76180%0.804SS**  trans-126126173.2-72.3-179.6179.4175.90108.3R320K318-R320 PolarHBondContact O-N 3.37Å; K318-R320 VanDerWaalsContact O-N 3.12Å
319P35Very low38Very low83 Ų83161.4 Ų161.454%0.53979%0.793SS.*  trans-62.2117.9168.726.2-32.5000108.8F321P319-F321 VanDerWaalsContact C-N 3.31Å; P319-F321 HydrophobicContact CB-CD2 4.36Å; P319-F321 HydrophobicContact CB-CE2 4.23Å; P319-F321 HydrophobicContact CG-CD2 4.36Å; P319-F321 HydrophobicContact CG-CE2 4.06Å; P319-F321 PolarHBondContact O-N 3.44Å
320R30.5Very low37.6Very low235 Ų235161.6 Ų161.689%0.88779%0.794SS**  trans-71.991.7165.4-83.1-174.6172.3-179.6-0.9107.6K318 V322K318-R320 PolarHBondContact O-N 3.37Å; K318-R320 VanDerWaalsContact O-N 3.12Å; R320-V322 PolarHBondContact O-N 3.15Å
321F33.8Very low37.2Very low185 Ų185154.8 Ų154.881%0.81178%0.779SS**  trans-60.6104.7161.9-83.3-87.6000108.4P319 H323P319-F321 VanDerWaalsContact C-N 3.31Å; P319-F321 HydrophobicContact CB-CD2 4.36Å; P319-F321 HydrophobicContact CB-CE2 4.23Å; P319-F321 HydrophobicContact CG-CD2 4.36Å; P319-F321 HydrophobicContact CG-CE2 4.06Å; P319-F321 PolarHBondContact O-N 3.44Å; F321-H323 PolarHBondContact O-N 3.44Å
322V33.2Very low36.9Very low125 Ų125152.2 Ų152.276%0.75877%0.768SS**  trans-68.4114.2171.6177.60000106.8R320 T324R320-V322 PolarHBondContact O-N 3.15Å; V322-T324 PolarHBondContact O-N 2.72Å
323H34.8Very low36.9Very low177 Ų177150 Ų15082%0.81976%0.758SS**  trans-61.7119.9164.2-86.1-65.7000108F321 R325F321-H323 PolarHBondContact O-N 3.44Å; H323-R325 PolarHBondContact O-N 2.79Å
324T36.5Very low36.1Very low140 Ų140152.8 Ų152.886%0.85975%0.747SS**  trans-57108.2168.637.60000108.7V322V322-T324 PolarHBondContact O-N 2.72Å
325R35.2Very low36.2Very low236 Ų236156.2 Ų156.289%0.89175%0.754SS**PPolyproline II helixtrans-68.6156.9164.9-76-177.4167.5-174.7-4.5108.4H323H323-R325 PolarHBondContact O-N 2.79Å
326Q37.5Very low36.5Very low190 Ų190152.9 Ų152.989%0.88875%0.745SS**PPolyproline II helixtrans-57.4148.7164-69.2169.4-98.600109.3R328Q326-R328 PolarHBondContact O-N 2.88Å
327T33.4Very low36.6Very low146 Ų146149.8 Ų149.890%0.89673%0.733SS**PPolyproline II helixtrans-55135.1-179.934.10000111.1
328R36.4Very low36.8Very low224 Ų224144.9 Ų144.985%0.84572%0.72SS**PPolyproline II helixtrans-101154.6162.8-163.6179.1-170.6-166.1-0.1106.6Q326Q326-R328 PolarHBondContact O-N 2.88Å
329S35.7Very low37.1Very low68 Ų68142.7 Ų142.748%0.47671%0.708SS.*PPolyproline II helixtrans-53.1146.3174.750.70000111.5
330L36.4Very low37.3Very low144 Ų144143.8 Ų143.875%0.75471%0.709SS**  trans-107.7108.7169.9-74.1170.6000107.2
331S37.6Very low37.8Very low71 Ų71137.9 Ų137.950%0.49769%0.694SS.*EExtended strand (participates in β ladder)trans-73.7130.7164.655.60000109Y339S331-Y339 WeakPolarHBondContact CA-O 3.27Å
332V42.7Very low38.1Very low89 Ų89135.8 Ų135.854%0.53969%0.691SS.*EExtended strand (participates in β ladder)trans-115.9136.4173.8-178.60000108.6Y339V332-Y339 PolarHBondContact N-O 3.26Å; V332-Y339 PolarHBondContact O-N 2.81Å; V332-Y339 VanDerWaalsContact O-N 3.08Å
333E39.8Very low38.5Very low136 Ų136137.6 Ų137.664%0.63670%0.696SS**EExtended strand (participates in β ladder)trans-106.8122.9-178.8-171.5170.9-121.400108.5E337 I338E333-E337 WeakPolarHBondContact CA-O 3.48Å; E333-I338 HydrophobicContact CB-CG1 4.29Å; E333-I338 HydrophobicContact CG-CG1 4.01Å
334F33.1Very low38.6Very low143 Ų143138.4 Ų138.463%0.62770%0.7SS**EExtended strand (participates in β ladder)trans-142.6133.1-180-168.1-95000109.2G336 E337F334-G336 PolarHBondContact O-N 2.64Å; F334-E337 PolarHBondContact N-O 3.04Å; F334-E337 VanDerWaalsContact N-O 3.16Å; F334-E337 PolarHBondContact O-N 3.01Å
335E39.9Very low38.5Very low185 Ų185140.8 Ų140.886%0.86470%0.701SS**THydrogen-bonded Turntrans5114.9-177.1-70.2-179169.300116.9
336G48.2Very low38.2Very low65 Ų65139 Ų13967%0.6770%0.703SS**THydrogen-bonded Turntrans106.50.4172.500000115.4F334F334-G336 PolarHBondContact O-N 2.64Å
337E37.6Very low37.7Very low120 Ų120139.5 Ų139.556%0.56171%0.705SS**EExtended strand (participates in β ladder)trans-111.4153.2168.5-68.7-164163.500111.7E333 F334 Y339E333-E337 WeakPolarHBondContact CA-O 3.48Å; F334-E337 PolarHBondContact N-O 3.04Å; F334-E337 VanDerWaalsContact N-O 3.16Å; F334-E337 PolarHBondContact O-N 3.01Å; E337-Y339 HydrophobicContact CB-CE1 4.28Å; E337-Y339 HydrophobicContact CB-CE2 3.95Å; E337-Y339 WeakPolarHBondContact CB-OH 3.36Å; E337-Y339 PolarHBondContact OE2-OH 2.88Å
338I41.2Very low37.6Very low106 Ų106141.9 Ų141.954%0.54471%0.707SS.*EExtended strand (participates in β ladder)trans-111.1121.4-177.2-58.1173000108.6E333E333-I338 HydrophobicContact CB-CG1 4.29Å; E333-I338 HydrophobicContact CG-CG1 4.01Å
339Y40.3Very low37.2Very low129 Ų129138.3 Ų138.351%0.50670%0.703SS.*EExtended strand (participates in β ladder)trans-112.8129.5178.8-55.5-71.1000111.3S331 V332 E337S331-Y339 WeakPolarHBondContact CA-O 3.27Å; V332-Y339 PolarHBondContact N-O 3.26Å; V332-Y339 PolarHBondContact O-N 2.81Å; V332-Y339 VanDerWaalsContact O-N 3.08Å; E337-Y339 HydrophobicContact CB-CE1 4.28Å; E337-Y339 HydrophobicContact CB-CE2 3.95Å; E337-Y339 WeakPolarHBondContact CB-OH 3.36Å; E337-Y339 PolarHBondContact OE2-OH 2.88Å
340D39.5Very low36.7Very low106 Ų106144.6 Ų144.657%0.56773%0.725SS**EExtended strand (participates in β ladder)trans-99.6121.3173.5-101.9-45.7000109.6
341I41.1Very low36.4Very low110 Ų110142.9 Ų142.956%0.56472%0.721SS**  trans-105.1116.6-178.8-54.7175.9000110L343I341-L343 HydrophobicContact CG2-CD2 4.34Å; I341-L343 HydrophobicContact CG2-CG 4.2Å
342N39.5Very low35.8Very low142 Ų142147.3 Ų147.376%0.75974%0.738SS**  trans-97143.4168.1-73.9-51.7000110.2
343L41.2Very low35.1Very low163 Ų163150.7 Ų150.785%0.85375%0.748SS**  trans-127.938.9-172.3-74.5170.4000113.1I341I341-L343 HydrophobicContact CG2-CD2 4.34Å; I341-L343 HydrophobicContact CG2-CG 4.2Å
344E37.3Very low34.7Very low194 Ų194149.1 Ų149.191%0.90775%0.749SS**SBendtrans-128.4-5.5175.5-69.8-164.8148.200115.4
345E34.4Very low34.2Very low190 Ų190153.1 Ų153.189%0.88876%0.76SS**  trans-141.783.3-179.1-68.3-171147.200113.4
346E29.2Very low33.9Very low198 Ų198152 Ų15293%0.92576%0.76SS**  trans-158.470.6161.4-151.8168.5-12300114.1
347E28.1Very low32.7Very low200 Ų200157.2 Ų157.294%0.93577%0.771SS**SBendtrans-161.466.1153-142.8177.1-145.300114.4
348E30Very low32.1Very low197 Ų197155.6 Ų155.692%0.92178%0.778SS**  trans-158.287.3152.5-147.3177.2-125.900112.3
349L27.4Very low31.4Very low148 Ų148159.8 Ų159.878%0.77579%0.792SS**  trans-155.294.9174.5-143.3151.3000115.2V351L349-V351 HydrophobicContact CD2-CG2 3.77Å; L349-V351 HydrophobicContact CG-CG2 4.5Å
350Q26.3Very low30.6Very low200 Ų200163.5 Ų163.594%0.93581%0.805SS**  trans-148.769.3146.2-121.7168.968.500112.6
351V29Very low29.9Very low109 Ų109165.8 Ų165.866%0.66181%0.812SS**  trans3.7128147.2173.90000117.3L349L349-V351 HydrophobicContact CD2-CG2 3.77Å; L349-V351 HydrophobicContact CG-CG2 4.5Å
352L25.1Very low29.3Very low164 Ų164166.7 Ų166.786%0.85982%0.818SS**  -158.2145.4118.4-103174.3000112.7
353Q28Very low28.6Very low160 Ų160168.9 Ų168.975%0.74882%0.824SS**  trans-132.3166.5178.9-85.7-88.2-15.500106.1
354P31.5Very low27.8Very low103 Ų103164.1 Ų164.167%0.66981%0.814SS**  cis-155.7-172.735.546.8-25.9000119.5
355R23.2Very low27.5Very low227 Ų227163.9 Ų163.986%0.85781%0.813SS**  trans88.3131.6149.2-78.6177.5-179.3176.50.9120.7
356N32.8Very low27.2Very low160 Ų160164.3 Ų164.386%0.85681%0.812SS**  trans-83.9148.3158.4-70.9-83.3000110.7
357I24.6Very low27Very low176 Ų176158.2 Ų158.290%0.90380%0.802SS**  trans-159.3162.6148.2-104.9155000107.6
358A24.4Very low27.6Very low85 Ų85154 Ų15470%0.70279%0.792SS**  trans-119.8168.4-164.300000114.9
359K26.4Very low27.5Very low194 Ų194155 Ų15584%0.84379%0.787SS**  trans81.5139156-80.3179175.1174.60120.4
360R23.8Very low27.6Very low207 Ų207153.7 Ų153.778%0.78178%0.781SS**  trans83.8131.6142.6-81.6179.2160-179.4-4.2120.9
361H25Very low27.8Very low154 Ų154150.7 Ų150.771%0.71377%0.771SS**  trans56.9151.5137.3-70.3-63.2000119.6
362D27.9Very low27.8Very low129 Ų129153.8 Ų153.869%0.6978%0.778SS**  cis-160.9176.9-20.7-143.4-43.3000108.5
363E25.1Very low27.9Very low189 Ų189150 Ų15088%0.88377%0.77SS**  trans62.5154.4169.1-59.4-167.7171.700117.8
364G25.3Very low27.8Very low63 Ų63147.6 Ų147.665%0.64977%0.771SS**  cis169.5134.5-12.400000114
365H30Very low27.7Very low189 Ų189148.7 Ų148.788%0.87578%0.781SS**  trans63.7155.8163.5-70.5-9.9000117.8
366K27.4Very low27.9Very low199 Ų199141.5 Ų141.587%0.86578%0.778SS**  cis-128.1158.71.7-65.3177.8-179.4173.30110.6
367G25.2Very low27.7Very low70 Ų70137.5 Ų137.572%0.72278%0.775SS**  trans-94.5-131.3167.400000112
368P41.7Very low27.9Very low112 Ų112137.2 Ų137.273%0.72778%0.775SS**  cis-149.8-176.411.744.6-24.5000118
369R28.1Very low28.2Very low216 Ų216145.4 Ų145.482%0.81579%0.787SS**  trans77.1142.7159.5-60.9-170.1174.7160.92.4118.3
370D27.9Very low28.3Very low122 Ų122139.6 Ų139.665%0.65278%0.783SS**  cis-167.6162.6-11.4-95.6-17.7000105.8
371L30.5Very low28.9Very low136 Ų136141 Ų14171%0.71279%0.788SS**  cis-163.4-177.6-8.1-103.2166.5000106
372Q29Very low29.1Very low175 Ų175142.4 Ų142.482%0.81880%0.797SS**  cis-139.7-80.96.7-169.2172.580.600113.5
373A27.4Very low29.4Very low84 Ų84143.8 Ų143.869%0.69480%0.804SS**  trans-163.1174.6-161.300000110.9
374S26.7Very low29.9Very low109 Ų109139.4 Ų139.476%0.76280%0.8SS**  cis-155.6132.418.2-169.70000114.8
375S28.8Very low30.1Very low126 Ų126143.3 Ų143.388%0.88181%0.806SS**  trans53.4157135.2-153.10000123.3
376G27.8Very low30.2Very low76 Ų76139.7 Ų139.778%0.78480%0.802SS**  trans120.3100169.800000113.9
377G28Very low30.9Very low77 Ų77135.1 Ų135.179%0.79480%0.795SS**  trans-118.2-168.3-174.900000115.8
378N28.8Very low31.6Very low170 Ų170139.5 Ų139.591%0.90980%0.802SS**  trans74.8101.8170.1-123.3-0.6000118G380N378-G380 PolarHBondContact O-N 2.73Å; N378-G380 VanDerWaalsContact O-N 3.14Å
379R31.5Very low31.2Very low256 Ų256138.9 Ų138.997%0.96681%0.806SS**  trans-80.284.7166.2-80.3-174.1169.8-172.7-2.5110.9
380G29.3Very low32.1Very low72 Ų72135.9 Ų135.974%0.74281%0.811SS**  trans-65.6133165.900000111.7N378N378-G380 PolarHBondContact O-N 2.73Å; N378-G380 VanDerWaalsContact O-N 3.14Å
381R36.3Very low32.6Very low236 Ų236132.5 Ų132.589%0.89181%0.805SS**  trans-92.7113.9176166.6-176.6160.9-167.7-5.7109.5
382M28.3Very low33.2Very low185 Ų185130.4 Ų130.491%0.91180%0.8SS**  trans-134.4160170.3-75-165.8166.900112.2
383L34.6Very low34.2Very low158 Ų158128.3 Ų128.383%0.82780%0.802SS**  trans-126.6143.1-176.7-79.4165.5000109.1
384A34.7Very low35.4Very low97 Ų97128.5 Ų128.580%0.80279%0.794SS**  trans61.2166.4176.200000114
385D30.5Very low36.7Very low145 Ų145125.9 Ų125.978%0.77577%0.774SS**  cis-143.7167.6-8.6-156.3-11000108.7
386S31.6Very low38.4Very low113 Ų113124.3 Ų124.379%0.7976%0.759SS**  trans169.2112.8142.4-80.80000112
387S42Very low40.2Very low102 Ų102128.4 Ų128.471%0.71375%0.751SS**  trans-66.4123.2152.751.80000110.9
388N39.6Very low41.9Very low162 Ų162128.7 Ų128.787%0.86674%0.736SS**  trans-171.7106.6144.7-99.6-29000112.3
389A34.3Very low44Very low100 Ų100121.1 Ų121.183%0.82670%0.697SS**  trans-15898163.500000109G391A389-G391 PolarHBondContact O-N 2.88Å
390V47.5Very low45.8Very low152 Ų152113.7 Ų113.792%0.92167%0.673SS**  trans-77.3106.5177.4-179.20000108.9
391G37Very low48.1Very low51 Ų51112.4 Ų112.453%0.52665%0.646SS.*  trans-117.9154.8172.700000111.5A389A389-G391 PolarHBondContact O-N 2.88Å
392P43.5Very low50.4Low92 Ų92101.5 Ų101.560%0.59761%0.607SS**  trans-63.9147.1-174.925.3-33.8000112.9T394P392-T394 PolarHBondContact O-N 2.85Å
393P49.6Very low53Low132 Ų13295.4 Ų95.486%0.85758%0.575SS**THydrogen-bonded Turntrans-76.920.1-157.631.7-38.9000116.2
394T52.2Low55.2Low88 Ų8890.7 Ų90.754%0.5455%0.55SS..THydrogen-bonded Turntrans-131.28.3-17148.90000114.8P392 P406P392-T394 PolarHBondContact O-N 2.85Å; T394-P406 VanDerWaalsContact OG1-CG 3.26Å; T394-P406 WeakPolarHBondContact OG1-CG 3.01Å
395T53.8Low57.4Low54 Ų5488.8 Ų88.833%0.33153%0.526SS..  trans-94.6127.4174.158.80000112.1I404 L405T395-I404 WeakPolarHBondContact CA-O 3.49Å; T395-L405 HydrophobicContact CG2-CD2 3.87Å
396V66.4Low59.4Low93 Ų9386.1 Ų86.156%0.56452%0.517SS*.EExtended strand (participates in β ladder)trans-90.1111.7174.9177.60000109.3V398 I404V396-V398 PolarHBondContact O-N 3.28Å; V396-I404 HydrophobicContact CB-CB 4.34Å; V396-I404 PolarHBondContact N-O 3.03Å; V396-I404 PolarHBondContact O-N 3.02Å
397R63.7Low61.5Low162 Ų16286 Ų8661%0.61151%0.507SS*.EExtended strand (participates in β ladder)trans-72.9117.4175-171.7174.6-161.4-179.710109.9T399 H400 F403R397-T399 WeakPolarHBondContact CG-O 3.41Å; R397-T399 PolarHBondContact NE-O 3.22Å; R397-H400 PolarHBondContact NH2-O 3.27Å; R397-F403 HydrophobicContact CB-CD1 4.04Å; R397-F403 HydrophobicContact CB-CE1 4.24Å; R397-F403 HydrophobicContact CG-CD1 3.89Å; R397-F403 HydrophobicContact CG-CE1 3.71Å
398V65.5Low63Low82 Ų8288.1 Ų88.150%0.49751%0.511SS..  trans-98.8-40-178.4-178.80000111.4V396 C402 I404V396-V398 PolarHBondContact O-N 3.28Å; V398-C402 PolarHBondContact N-O 3.29Å; V398-C402 VanDerWaalsContact N-O 3.09Å; V398-I404 HydrophobicContact CG2-CD1 3.56Å; V398-I404 HydrophobicContact CG2-CG1 3.72Å
399T71.9Confident64.7Low12 Ų1282.7 Ų82.77%0.07449%0.485CS..SBendtrans-133.8-177.4167.777.20000110.6R397 K401 C402 H426 Y429 I430R397-T399 WeakPolarHBondContact CG-O 3.41Å; R397-T399 PolarHBondContact NE-O 3.22Å; T399-K401 PolarHBondContact O-N 3.07Å; T399-K401 PolarHBondContact OG1-N 3.45Å; T399-C402 PolarHBondContact N-O 2.9Å; T399-C402 PolarHBondContact OG1-N 2.79Å; T399-C402 VanDerWaalsContact OG1-N 3.12Å; T399-H426 PolarHBondContact OG1-CE1 2.94Å; T399-H426 VanDerWaalsContact OG1-CE1 3.3Å; T399-H426 PolarHBondContact OG1-NE2 2.93Å; T399-Y429 HydrophobicContact CG2-CE1 4.37Å; T399-I430 HydrophobicContact CG2-CD1 3.9Å; T399-I430 HydrophobicContact CG2-CG1 3.5Å
400H70.4Confident67.1Low100 Ų10083.9 Ų83.946%0.46348%0.476SS..SBendtrans-65.1-26.517460.8-82.2000113.1R397R397-H400 PolarHBondContact NH2-O 3.27Å
401K77.6Confident68.7Low44 Ų4482 Ų8219%0.19146%0.457CS..SBendtrans-112.2-2.8-178.5-60.6-166.2166.1-90.60116.2T399 C412 E413 E415 L416T399-K401 PolarHBondContact O-N 3.07Å; T399-K401 PolarHBondContact OG1-N 3.45Å; K401-C412 WeakPolarHBondContact O-CA 3.4Å; K401-E413 WeakPolarHBondContact CA-OE1 3.37Å; K401-E413 HydrophobicContact CB-CB 4.3Å; K401-E413 HydrophobicContact CB-CG 4.14Å; K401-E413 VanDerWaalsContact CD-OE2 3.24Å; K401-E413 WeakPolarHBondContact CD-OE2 3.36Å; K401-E413 WeakPolarHBondContact CE-OE2 3.47Å; K401-E413 WeakPolarHBondContact CG-OE2 3.07Å; K401-E413 IonicContact NZ-OE2 2.65Å; K401-E413 PolarHBondContact NZ-OE2 2.87Å; K401-E413 PolarHBondContact O-N 3.17Å; K401-E415 IonicContact NZ-OE2 2.7Å; K401-E415 PolarHBondContact NZ-OE2 3.31Å; K401-L416 HydrophobicContact CB-CD1 3.79Å; K401-L416 HydrophobicContact CD-CD1 4.28Å; K401-L416 HydrophobicContact CD-CD2 4.03Å; K401-L416 HydrophobicContact CD-CG 4.1Å
402C83.2Confident71.1Confident8 Ų880.4 Ų80.45%0.05444%0.438CS..EExtended strand (participates in β ladder)trans-136.9139-176.5-70.50000113.2V398 T399 H411 C412 H426V398-C402 PolarHBondContact N-O 3.29Å; V398-C402 VanDerWaalsContact N-O 3.09Å; T399-C402 PolarHBondContact N-O 2.9Å; T399-C402 PolarHBondContact OG1-N 2.79Å; T399-C402 VanDerWaalsContact OG1-N 3.12Å; C402-H411 CarbonylContact C-O 3.53Å; C402-H411 WeakPolarHBondContact CA-O 3.34Å; C402-C412 HydrophobicContact CB-CB 4.23Å; C402-C412 WeakPolarHBondContact CB-SG 3.27Å; C402-C412 WeakPolarHBondContact SG-CB 3.4Å; C402-C412 CovalentContact SG-SG 2.04Å; C402-C412 PolarHBondContact SG-SG 3.21Å; C402-H426 VanDerWaalsContact SG-CE1 3.57Å
403F82.9Confident73.1Confident57 Ų5779.2 Ų79.225%0.2542%0.424CS..EExtended strand (participates in β ladder)trans-135.4142.2-170.8-50.9-95.9000110.3R397 H411R397-F403 HydrophobicContact CB-CD1 4.04Å; R397-F403 HydrophobicContact CB-CE1 4.24Å; R397-F403 HydrophobicContact CG-CD1 3.89Å; R397-F403 HydrophobicContact CG-CE1 3.71Å; F403-H411 PolarHBondContact N-O 3.06Å; F403-H411 PolarHBondContact O-N 3.38Å
404I81.9Confident74.4Confident58 Ų5882.8 Ų82.830%0.29742%0.421SS..EExtended strand (participates in β ladder)trans-90.9124.6165.6-65.8167.7000107.6T395 V396 V398 I410T395-I404 WeakPolarHBondContact CA-O 3.49Å; V396-I404 HydrophobicContact CB-CB 4.34Å; V396-I404 PolarHBondContact N-O 3.03Å; V396-I404 PolarHBondContact O-N 3.02Å; V398-I404 HydrophobicContact CG2-CD1 3.56Å; V398-I404 HydrophobicContact CG2-CG1 3.72Å; I404-I410 HydrophobicContact CG1-CG1 4.44Å
405L80.8Confident75.6Confident57 Ų5783.7 Ų83.730%0.29842%0.419SS..  trans-82.9163.7175.3-66.2178.2000111.1T395 N407 D408 S409 H411T395-L405 HydrophobicContact CG2-CD2 3.87Å; L405-N407 VanDerWaalsContact CB-OD1 3.26Å; L405-N407 WeakPolarHBondContact CB-OD1 3.48Å; L405-N407 PolarHBondContact O-N 3.25Å; L405-D408 PolarHBondContact O-N 3.16Å; L405-S409 WeakPolarHBondContact CB-O 3.09Å; L405-S409 PolarHBondContact N-O 2.79Å; L405-H411 HydrophobicContact CD1-CB 4Å; L405-H411 HydrophobicContact CG-CB 4.17Å
406P72.8Confident76.7Confident89 Ų8981.7 Ų81.758%0.57841%0.406SS*.THydrogen-bonded Turntrans-67.70.8-174.1-18.732.6000115.5T394T394-P406 VanDerWaalsContact OG1-CG 3.26Å; T394-P406 WeakPolarHBondContact OG1-CG 3.01Å
407N75.7Confident77.4Confident111 Ų11184.3 Ų84.359%0.59441%0.407SS*.THydrogen-bonded Turntrans-113.823.4-179.766.6-14.5000111.9L405 S409L405-N407 VanDerWaalsContact CB-OD1 3.26Å; L405-N407 WeakPolarHBondContact CB-OD1 3.48Å; L405-N407 PolarHBondContact O-N 3.25Å; N407-S409 VanDerWaalsContact CG-OG 3.31Å; N407-S409 PolarHBondContact ND2-OG 2.89Å; N407-S409 PolarHBondContact O-N 2.76Å; N407-S409 WeakPolarHBondContact OD1-CB 3.37Å; N407-S409 PolarHBondContact OD1-N 2.83Å; N407-S409 PolarHBondContact OD1-OG 3.43Å
408D72.6Confident78.1Confident147 Ų14783.5 Ų83.579%0.78641%0.41SS*.SBendtrans56.57.8-173.8-66.7-34.2000115.7L405L405-D408 PolarHBondContact O-N 3.16Å
409S74.7Confident79.1Confident47 Ų4782.1 Ų82.133%0.32940%0.404SS..  trans-81.6142.6174.774.90000111.5L405 N407L405-S409 WeakPolarHBondContact CB-O 3.09Å; L405-S409 PolarHBondContact N-O 2.79Å; N407-S409 VanDerWaalsContact CG-OG 3.31Å; N407-S409 PolarHBondContact ND2-OG 2.89Å; N407-S409 PolarHBondContact O-N 2.76Å; N407-S409 WeakPolarHBondContact OD1-CB 3.37Å; N407-S409 PolarHBondContact OD1-N 2.83Å; N407-S409 PolarHBondContact OD1-OG 3.43Å
410I86.1Confident79.3Confident125 Ų12585.7 Ų85.764%0.64144%0.435SS*.EExtended strand (participates in β ladder)trans-95.9123.5-178.8-57.8174.9000108.8I404I404-I410 HydrophobicContact CG1-CG1 4.44Å
411H81Confident79.8Confident112 Ų11289.9 Ų89.952%0.51945%0.446SS..EExtended strand (participates in β ladder)trans-108.9130.7171.7-169.277.1000110.2C402 F403 L405C402-H411 CarbonylContact C-O 3.53Å; C402-H411 WeakPolarHBondContact CA-O 3.34Å; F403-H411 PolarHBondContact N-O 3.06Å; F403-H411 PolarHBondContact O-N 3.38Å; L405-H411 HydrophobicContact CD1-CB 4Å; L405-H411 HydrophobicContact CG-CB 4.17Å
412C87.9Confident79.9Confident18 Ų1889.6 Ų89.612%0.12245%0.452CS..EExtended strand (participates in β ladder)trans-134.4144.9-179.2-73.40000109.9K401 C402 L416 Y417K401-C412 WeakPolarHBondContact O-CA 3.4Å; C402-C412 HydrophobicContact CB-CB 4.23Å; C402-C412 WeakPolarHBondContact CB-SG 3.27Å; C402-C412 WeakPolarHBondContact SG-CB 3.4Å; C402-C412 CovalentContact SG-SG 2.04Å; C402-C412 PolarHBondContact SG-SG 3.21Å; C412-L416 HydrophobicContact CB-CD1 4.02Å; C412-Y417 HydrophobicContact CB-CE2 3.85Å
413E85.2Confident80.1Confident67 Ų6795.3 Ų95.331%0.31347%0.473SS..  trans-55.7136.9179.6-71.1171.5-161.800112.8K401 E415 L416K401-E413 WeakPolarHBondContact CA-OE1 3.37Å; K401-E413 HydrophobicContact CB-CB 4.3Å; K401-E413 HydrophobicContact CB-CG 4.14Å; K401-E413 VanDerWaalsContact CD-OE2 3.24Å; K401-E413 WeakPolarHBondContact CD-OE2 3.36Å; K401-E413 WeakPolarHBondContact CE-OE2 3.47Å; K401-E413 WeakPolarHBondContact CG-OE2 3.07Å; K401-E413 IonicContact NZ-OE2 2.65Å; K401-E413 PolarHBondContact NZ-OE2 2.87Å; K401-E413 PolarHBondContact O-N 3.17Å; E413-E415 PolarHBondContact O-N 2.63Å; E413-E415 VanDerWaalsContact O-N 3.14Å; E413-L416 WeakPolarHBondContact O-CB 3.06Å; E413-L416 PolarHBondContact O-N 2.94Å
414R77Confident80.1Confident207 Ų20799.5 Ų99.578%0.78149%0.491SS*.THydrogen-bonded Turntrans-60.2-30.5-170.8-155.9176.4-164.6174.15.3113.6L416 Y417 Q418R414-L416 PolarHBondContact O-N 2.88Å; R414-Y417 PolarHBondContact O-N 2.92Å; R414-Y417 VanDerWaalsContact O-N 3.08Å; R414-Q418 PolarHBondContact O-N 3.03Å
415E76Confident80.3Confident108 Ų108101.1 Ų101.151%0.50550%0.5SS..Hα-helixtrans-53-36.6175.2-59.3178.3167.500112.9K401 E413 Y417 Q418K401-E415 IonicContact NZ-OE2 2.7Å; K401-E415 PolarHBondContact NZ-OE2 3.31Å; E413-E415 PolarHBondContact O-N 2.63Å; E413-E415 VanDerWaalsContact O-N 3.14Å; E415-Y417 PolarHBondContact O-N 3.04Å; E415-Y417 VanDerWaalsContact O-N 3.15Å; E415-Q418 PolarHBondContact O-N 3.01Å; E415-Q418 VanDerWaalsContact O-N 3.12Å
416L78.4Confident80.4Confident11 Ų1199.5 Ų99.56%0.05849%0.491CS..Hα-helixtrans-62.6-22.2-179.6-71.1170.6000113.1K401 C412 E413 R414 W423 H426K401-L416 HydrophobicContact CB-CD1 3.79Å; K401-L416 HydrophobicContact CD-CD1 4.28Å; K401-L416 HydrophobicContact CD-CD2 4.03Å; K401-L416 HydrophobicContact CD-CG 4.1Å; C412-L416 HydrophobicContact CB-CD1 4.02Å; E413-L416 WeakPolarHBondContact O-CB 3.06Å; E413-L416 PolarHBondContact O-N 2.94Å; R414-L416 PolarHBondContact O-N 2.88Å; L416-W423 WeakPolarHBondContact O-CA 3.42Å; L416-W423 VanDerWaalsContact O-CB 3.28Å; L416-W423 WeakPolarHBondContact O-CB 2.99Å; L416-H426 HydrophobicContact CD2-CB 3.47Å; L416-H426 VanDerWaalsContact CD2-CB 3.47Å
417Y80.8Confident81.1Confident148 Ų14899.4 Ų99.458%0.5848%0.482SS*.Hα-helixtrans-103-7.8179.4-57-78.9000113.1C412 R414 E415C412-Y417 HydrophobicContact CB-CE2 3.85Å; R414-Y417 PolarHBondContact O-N 2.92Å; R414-Y417 VanDerWaalsContact O-N 3.08Å; E415-Y417 PolarHBondContact O-N 3.04Å; E415-Y417 VanDerWaalsContact O-N 3.15Å
418Q78.3Confident81.5Confident145 Ų14596 Ų9668%0.67847%0.469SS*.Hα-helixtrans-82-18.6178.2-71.7172.4-20.900113.1R414 E415R414-Q418 PolarHBondContact O-N 3.03Å; E415-Q418 PolarHBondContact O-N 3.01Å; E415-Q418 VanDerWaalsContact O-N 3.12Å
419S85.4Confident82.2Confident54 Ų5493.9 Ų93.938%0.37845%0.451SS..  trans-135.5121.4177.71730000111.2R421 A422 W423S419-R421 PolarHBondContact O-N 3.2Å; S419-R421 VanDerWaalsContact O-N 3.14Å; S419-R421 PolarHBondContact OG-N 3.11Å; S419-A422 PolarHBondContact O-N 2.83Å; S419-A422 VanDerWaalsContact O-N 3.11Å; S419-A422 PolarHBondContact OG-N 2.03Å; S419-W423 PolarHBondContact O-N 2.9Å
420A77.6Confident82.7Confident87 Ų8793.9 Ų93.972%0.71945%0.446SS*.Hα-helixtrans-59.9-25.4177.200000112.7K424A420-K424 WeakPolarHBondContact O-CB 3.48Å; A420-K424 PolarHBondContact O-N 3.13Å; A420-K424 VanDerWaalsContact O-N 3.15Å
421R80.8Confident82.5Confident187 Ų18791.5 Ų91.571%0.70644%0.435SS*.Hα-helixtrans-73.9-49.3173.9-171.3171.1-174.5160.52.6111.4S419 W423 K424 D425S419-R421 PolarHBondContact O-N 3.2Å; S419-R421 VanDerWaalsContact O-N 3.14Å; S419-R421 PolarHBondContact OG-N 3.11Å; R421-W423 VanDerWaalsContact C-N 3.29Å; R421-W423 PolarHBondContact O-N 3.34Å; R421-K424 PolarHBondContact O-N 2.89Å; R421-K424 VanDerWaalsContact O-N 3.15Å; R421-D425 WeakPolarHBondContact CG-OD2 3.38Å; R421-D425 WeakPolarHBondContact O-CB 3.34Å; R421-D425 VanDerWaalsContact O-CG 3.25Å; R421-D425 PolarHBondContact O-N 2.93Å
422A78.7Confident82.7Confident38 Ų3893 Ų9331%0.31444%0.44SS..Hα-helixtrans-59.6-40.2176.200000112.1S419 H426S419-A422 PolarHBondContact O-N 2.83Å; S419-A422 VanDerWaalsContact O-N 3.11Å; S419-A422 PolarHBondContact OG-N 2.03Å; A422-H426 WeakPolarHBondContact O-CB 3.5Å; A422-H426 PolarHBondContact O-N 3.29Å
423W86.9Confident82.5Confident129 Ų12996.4 Ų96.449%0.48945%0.454SS..Hα-helixtrans-57.6-52172.3-174.482.4000112.2L416 S419 R421 H426 K427L416-W423 WeakPolarHBondContact O-CA 3.42Å; L416-W423 VanDerWaalsContact O-CB 3.28Å; L416-W423 WeakPolarHBondContact O-CB 2.99Å; S419-W423 PolarHBondContact O-N 2.9Å; R421-W423 VanDerWaalsContact C-N 3.29Å; R421-W423 PolarHBondContact O-N 3.34Å; W423-H426 PolarHBondContact O-N 3.34Å; W423-K427 HydrophobicContact CH2-CD 3.99Å; W423-K427 HydrophobicContact CZ2-CD 4.42Å; W423-K427 HydrophobicContact CZ3-CD 4.32Å; W423-K427 WeakPolarHBondContact O-CB 3.48Å; W423-K427 PolarHBondContact O-N 3.16Å
424K84.3Confident82.6Confident144 Ų14497.1 Ų97.163%0.62646%0.459SS*.Hα-helixtrans-63.6-43-177.8-174.1177.5-179.8-179.70111.8A420 R421 K427 A428A420-K424 WeakPolarHBondContact O-CB 3.48Å; A420-K424 PolarHBondContact O-N 3.13Å; A420-K424 VanDerWaalsContact O-N 3.15Å; R421-K424 PolarHBondContact O-N 2.89Å; R421-K424 VanDerWaalsContact O-N 3.15Å; K424-K427 PolarHBondContact O-N 3.28Å; K424-A428 WeakPolarHBondContact O-CB 3.26Å; K424-A428 PolarHBondContact O-N 3.14Å
425D84.5Confident83Confident92 Ų9294 Ų9449%0.49245%0.453SS..Hα-helixtrans-68.8-42.1-178.9-66.2-21.7000111.3R421 A428 Y429R421-D425 WeakPolarHBondContact CG-OD2 3.38Å; R421-D425 WeakPolarHBondContact O-CB 3.34Å; R421-D425 VanDerWaalsContact O-CG 3.25Å; R421-D425 PolarHBondContact O-N 2.93Å; D425-A428 PolarHBondContact O-N 3.49Å; D425-Y429 PolarHBondContact O-N 3.31Å
426H84.4Confident83.5Confident23 Ų2391.5 Ų91.511%0.10645%0.451CS..Hα-helixtrans-70.7-35.4175.4-174.2-103.7000112.8T399 C402 L416 A422 W423 Y429 I430T399-H426 PolarHBondContact OG1-CE1 2.94Å; T399-H426 VanDerWaalsContact OG1-CE1 3.3Å; T399-H426 PolarHBondContact OG1-NE2 2.93Å; C402-H426 VanDerWaalsContact SG-CE1 3.57Å; L416-H426 HydrophobicContact CD2-CB 3.47Å; L416-H426 VanDerWaalsContact CD2-CB 3.47Å; A422-H426 WeakPolarHBondContact O-CB 3.5Å; A422-H426 PolarHBondContact O-N 3.29Å; W423-H426 PolarHBondContact O-N 3.34Å; H426-Y429 WeakPolarHBondContact O-CB 3.41Å; H426-Y429 PolarHBondContact O-N 2.96Å; H426-I430 PolarHBondContact O-N 2.89Å
427K87.6Confident83.9Confident87 Ų8795 Ų9538%0.37847%0.469SS..Hα-helixtrans-61.4-47.2170.7-169.3-157.5175.8-58.40110.9W423 K424 Y429 I430 D431W423-K427 HydrophobicContact CH2-CD 3.99Å; W423-K427 HydrophobicContact CZ2-CD 4.42Å; W423-K427 HydrophobicContact CZ3-CD 4.32Å; W423-K427 WeakPolarHBondContact O-CB 3.48Å; W423-K427 PolarHBondContact O-N 3.16Å; K424-K427 PolarHBondContact O-N 3.28Å; K427-Y429 PolarHBondContact O-N 3.48Å; K427-I430 WeakPolarHBondContact O-CB 3.49Å; K427-I430 PolarHBondContact O-N 2.8Å; K427-I430 VanDerWaalsContact O-N 3.1Å; K427-D431 IonicContact NZ-OD1 3.33Å; K427-D431 PolarHBondContact NZ-OD1 3.16Å; K427-D431 IonicContact NZ-OD2 2.89Å; K427-D431 PolarHBondContact NZ-OD2 3.48Å; K427-D431 VanDerWaalsContact O-CG 3.26Å; K427-D431 PolarHBondContact O-N 3.38Å
428A83.8Confident84Confident39 Ų3993.9 Ų93.932%0.32247%0.47SS..Hα-helixtrans-65.3-25.1179.100000113.1K424 D425 K432K424-A428 WeakPolarHBondContact O-CB 3.26Å; K424-A428 PolarHBondContact O-N 3.14Å; D425-A428 PolarHBondContact O-N 3.49Å; A428-K432 WeakPolarHBondContact O-CD 3.47Å; A428-K432 VanDerWaalsContact O-CG 3.31Å; A428-K432 WeakPolarHBondContact O-CG 3.3Å; A428-K432 PolarHBondContact O-N 2.78Å
429Y86.1Confident84.5Confident104 Ų10490.6 Ų90.641%0.40846%0.457SS..Hα-helixtrans-69.3-48.2168.4171.6-109.3000111.9T399 D425 H426 K427 D431 K432 E433T399-Y429 HydrophobicContact CG2-CE1 4.37Å; D425-Y429 PolarHBondContact O-N 3.31Å; H426-Y429 WeakPolarHBondContact O-CB 3.41Å; H426-Y429 PolarHBondContact O-N 2.96Å; K427-Y429 PolarHBondContact O-N 3.48Å; Y429-D431 PolarHBondContact O-N 2.8Å; Y429-K432 PolarHBondContact O-N 3.49Å; Y429-E433 PolarHBondContact O-N 3.17Å; Y429-E433 VanDerWaalsContact O-N 3.09Å
430I85.3Confident84.6Confident46 Ų4694.7 Ų94.724%0.23647%0.468CS..Hα-helixtrans-58.3-46.9175.4-71.9164.1000111.6T399 H426 K427 K432 E433 I434T399-I430 HydrophobicContact CG2-CD1 3.9Å; T399-I430 HydrophobicContact CG2-CG1 3.5Å; H426-I430 PolarHBondContact O-N 2.89Å; K427-I430 WeakPolarHBondContact O-CB 3.49Å; K427-I430 PolarHBondContact O-N 2.8Å; K427-I430 VanDerWaalsContact O-N 3.1Å; I430-K432 VanDerWaalsContact C-N 3.25Å; I430-K432 PolarHBondContact O-N 3.4Å; I430-E433 PolarHBondContact O-N 2.9Å; I430-I434 HydrophobicContact CG2-CD1 3.7Å; I430-I434 HydrophobicContact CG2-CG1 4.38Å; I430-I434 WeakPolarHBondContact O-CG1 3.28Å; I430-I434 PolarHBondContact O-N 2.97Å
431D81.8Confident85.2Confident76 Ų7694.6 Ų94.641%0.40645%0.454SS..Hα-helixtrans-57.6-39.1-179.1-64.4-33.7000111.6K427 Y429 E435K427-D431 IonicContact NZ-OD1 3.33Å; K427-D431 PolarHBondContact NZ-OD1 3.16Å; K427-D431 IonicContact NZ-OD2 2.89Å; K427-D431 PolarHBondContact NZ-OD2 3.48Å; K427-D431 VanDerWaalsContact O-CG 3.26Å; K427-D431 PolarHBondContact O-N 3.38Å; Y429-D431 PolarHBondContact O-N 2.8Å; D431-E435 PolarHBondContact O-N 2.94Å
432K85.9Confident85.5Confident144 Ų14491.4 Ų91.463%0.62645%0.445SS*.Hα-helixtrans-71.3-41.2177.4-74.1171.2-179173.60113.3A428 Y429 I430 I434 E435 A436A428-K432 WeakPolarHBondContact O-CD 3.47Å; A428-K432 VanDerWaalsContact O-CG 3.31Å; A428-K432 WeakPolarHBondContact O-CG 3.3Å; A428-K432 PolarHBondContact O-N 2.78Å; Y429-K432 PolarHBondContact O-N 3.49Å; I430-K432 VanDerWaalsContact C-N 3.25Å; I430-K432 PolarHBondContact O-N 3.4Å; K432-I434 VanDerWaalsContact C-N 3.28Å; K432-I434 PolarHBondContact O-N 2.86Å; K432-E435 PolarHBondContact O-N 3.12Å; K432-A436 PolarHBondContact O-N 3.23Å
433E84.1Confident85.9Confident89 Ų8993.7 Ų93.742%0.41645%0.452SS..Hα-helixtrans-65.4-36.8178.4-163.563.2-14600110.7Y429 I430 A436 L437Y429-E433 PolarHBondContact O-N 3.17Å; Y429-E433 VanDerWaalsContact O-N 3.09Å; I430-E433 PolarHBondContact O-N 2.9Å; E433-A436 PolarHBondContact O-N 3.49Å; E433-L437 HydrophobicContact CG-CD1 4.3Å; E433-L437 WeakPolarHBondContact O-CB 3.47Å; E433-L437 VanDerWaalsContact O-CG 3.28Å; E433-L437 WeakPolarHBondContact O-CG 3.39Å; E433-L437 PolarHBondContact O-N 3.11Å
434I86Confident86Confident82 Ų8292.8 Ų92.842%0.42146%0.457SS..Hα-helixtrans-60.7-46.9172-69.2168.5000111.2I430 K432 L437 Q438I430-I434 HydrophobicContact CG2-CD1 3.7Å; I430-I434 HydrophobicContact CG2-CG1 4.38Å; I430-I434 WeakPolarHBondContact O-CG1 3.28Å; I430-I434 PolarHBondContact O-N 2.97Å; K432-I434 VanDerWaalsContact C-N 3.28Å; K432-I434 PolarHBondContact O-N 2.86Å; I434-L437 PolarHBondContact O-N 2.93Å; I434-Q438 HydrophobicContact CG2-CG 4.46Å; I434-Q438 VanDerWaalsContact CG2-NE2 3.27Å; I434-Q438 WeakPolarHBondContact O-CB 3.33Å; I434-Q438 VanDerWaalsContact O-CG 3.3Å; I434-Q438 WeakPolarHBondContact O-CG 3.41Å; I434-Q438 PolarHBondContact O-N 2.77Å
435E86.5Confident86.1Confident140 Ų14093.8 Ų93.865%0.65446%0.457SS*.Hα-helixtrans-61-46.7177.9-173.2173.5-150.900111.6D431 K432 L437 Q438 D439D431-E435 PolarHBondContact O-N 2.94Å; K432-E435 PolarHBondContact O-N 3.12Å; E435-L437 PolarHBondContact O-N 2.89Å; E435-Q438 PolarHBondContact O-N 3.33Å; E435-D439 PolarHBondContact O-N 2.92Å
436A85.4Confident86.2Confident56 Ų5695.7 Ų95.746%0.46346%0.462SS..Hα-helixtrans-60.7-42.1177.800000112.7K432 E433 K440K432-A436 PolarHBondContact O-N 3.23Å; E433-A436 PolarHBondContact O-N 3.49Å; A436-K440 WeakPolarHBondContact O-CB 3.33Å; A436-K440 PolarHBondContact O-N 3.5Å
437L87.3Confident86.4Confident84 Ų8498.4 Ų98.444%0.4448%0.481SS..Hα-helixtrans-69.1-37.2176.4-71.5171.7000112.4E433 I434 E435 K440 I441E433-L437 HydrophobicContact CG-CD1 4.3Å; E433-L437 WeakPolarHBondContact O-CB 3.47Å; E433-L437 VanDerWaalsContact O-CG 3.28Å; E433-L437 WeakPolarHBondContact O-CG 3.39Å; E433-L437 PolarHBondContact O-N 3.11Å; I434-L437 PolarHBondContact O-N 2.93Å; E435-L437 PolarHBondContact O-N 2.89Å; L437-K440 PolarHBondContact O-N 2.79Å; L437-I441 WeakPolarHBondContact O-CB 3.39Å; L437-I441 VanDerWaalsContact O-CG1 3.28Å; L437-I441 WeakPolarHBondContact O-CG1 3.33Å; L437-I441 PolarHBondContact O-N 3.15Å
438Q84.4Confident86.4Confident125 Ų125101.8 Ų101.858%0.58449%0.491SS*.Hα-helixtrans-63.4-44.2175.1-75.7-177.530.300112I434 E435 I441 K442I434-Q438 HydrophobicContact CG2-CG 4.46Å; I434-Q438 VanDerWaalsContact CG2-NE2 3.27Å; I434-Q438 WeakPolarHBondContact O-CB 3.33Å; I434-Q438 VanDerWaalsContact O-CG 3.3Å; I434-Q438 WeakPolarHBondContact O-CG 3.41Å; I434-Q438 PolarHBondContact O-N 2.77Å; E435-Q438 PolarHBondContact O-N 3.33Å; Q438-I441 PolarHBondContact O-N 3.09Å; Q438-K442 WeakPolarHBondContact O-CB 3.36Å; Q438-K442 PolarHBondContact O-N 3.2Å
439D87.2Confident86.3Confident77 Ų77101.1 Ų101.141%0.41249%0.488SS..Hα-helixtrans-68.6-35.2176.8-115.79.7000111.8E435 K442 N443E435-D439 PolarHBondContact O-N 2.92Å; D439-K442 WeakPolarHBondContact O-CB 3.39Å; D439-K442 PolarHBondContact O-N 2.88Å; D439-K442 WeakPolarHBondContact OD1-CD 3.45Å; D439-K442 WeakPolarHBondContact OD1-CE 3.18Å; D439-K442 IonicContact OD1-NZ 3.52Å; D439-K442 PolarHBondContact OD1-NZ 3.02Å; D439-K442 IonicContact OD2-NZ 3.44Å; D439-N443 WeakPolarHBondContact O-CB 3.41Å; D439-N443 PolarHBondContact O-N 2.82Å; D439-N443 PolarHBondContact O-ND2 3.39Å
440K88.3Confident86.1Confident139 Ų139100.7 Ų100.760%0.60449%0.489SS*.Hα-helixtrans-61.7-43.1171.1-164.6172.1-174.6176.10112A436 L437 N443 L444A436-K440 WeakPolarHBondContact O-CB 3.33Å; A436-K440 PolarHBondContact O-N 3.5Å; L437-K440 PolarHBondContact O-N 2.79Å; K440-N443 PolarHBondContact O-N 2.76Å; K440-L444 HydrophobicContact CG-CD1 4.47Å; K440-L444 WeakPolarHBondContact O-CB 3.42Å; K440-L444 VanDerWaalsContact O-CG 3.3Å; K440-L444 WeakPolarHBondContact O-CG 3.28Å; K440-L444 PolarHBondContact O-N 3.27Å
441I89.3Confident86Confident85 Ų85104 Ų10444%0.43651%0.507SS..Hα-helixtrans-63.7-40.5174.3-73165.3000111.3L437 Q438 L444 R445L437-I441 WeakPolarHBondContact O-CB 3.39Å; L437-I441 VanDerWaalsContact O-CG1 3.28Å; L437-I441 WeakPolarHBondContact O-CG1 3.33Å; L437-I441 PolarHBondContact O-N 3.15Å; Q438-I441 PolarHBondContact O-N 3.09Å; I441-L444 PolarHBondContact O-N 3.27Å; I441-R445 HydrophobicContact CG2-CG 4.46Å; I441-R445 WeakPolarHBondContact O-CB 3.37Å; I441-R445 VanDerWaalsContact O-CG 3.24Å; I441-R445 WeakPolarHBondContact O-CG 3.43Å; I441-R445 PolarHBondContact O-N 2.82Å
442K88.8Confident85.7Confident120 Ų120108.5 Ų108.552%0.52252%0.523SS..Hα-helixtrans-63.2-46.9176.7173.9175.8137-148.80111.7Q438 D439 L444 R445 E446Q438-K442 WeakPolarHBondContact O-CB 3.36Å; Q438-K442 PolarHBondContact O-N 3.2Å; D439-K442 WeakPolarHBondContact O-CB 3.39Å; D439-K442 PolarHBondContact O-N 2.88Å; D439-K442 WeakPolarHBondContact OD1-CD 3.45Å; D439-K442 WeakPolarHBondContact OD1-CE 3.18Å; D439-K442 IonicContact OD1-NZ 3.52Å; D439-K442 PolarHBondContact OD1-NZ 3.02Å; D439-K442 IonicContact OD2-NZ 3.44Å; K442-L444 PolarHBondContact O-N 3.17Å; K442-R445 WeakPolarHBondContact O-CB 3.24Å; K442-R445 PolarHBondContact O-N 3.2Å; K442-E446 PolarHBondContact O-N 3.29Å
443N86.3Confident85.3Confident86 Ų86110.5 Ų110.546%0.4653%0.527SS..Hα-helixtrans-61.4-43.6175.5-65.2-18.7000111.5D439 K440 R445 E446 V447D439-N443 WeakPolarHBondContact O-CB 3.41Å; D439-N443 PolarHBondContact O-N 2.82Å; D439-N443 PolarHBondContact O-ND2 3.39Å; K440-N443 PolarHBondContact O-N 2.76Å; N443-R445 VanDerWaalsContact C-N 3.35Å; N443-R445 PolarHBondContact O-N 3.36Å; N443-E446 PolarHBondContact O-N 3.31Å; N443-V447 WeakPolarHBondContact O-CG2 3.5Å; N443-V447 PolarHBondContact O-N 3.23Å
444L88.2Confident84.7Confident111 Ų111115.3 Ų115.358%0.58154%0.541SS*.Hα-helixtrans-64.7-34.9174.7-71.7169.7000113K440 I441 K442 R448K440-L444 HydrophobicContact CG-CD1 4.47Å; K440-L444 WeakPolarHBondContact O-CB 3.42Å; K440-L444 VanDerWaalsContact O-CG 3.3Å; K440-L444 WeakPolarHBondContact O-CG 3.28Å; K440-L444 PolarHBondContact O-N 3.27Å; I441-L444 PolarHBondContact O-N 3.27Å; K442-L444 PolarHBondContact O-N 3.17Å; L444-R448 VanDerWaalsContact O-CB 3.25Å; L444-R448 WeakPolarHBondContact O-CB 3.41Å; L444-R448 PolarHBondContact O-N 3.25Å
445R87Confident84Confident165 Ų165117.9 Ų117.962%0.62355%0.549SS*.Hα-helixtrans-65-38.5172.4-75.2169.1-177.8-166.83.3111.7I441 K442 N443 G449I441-R445 HydrophobicContact CG2-CG 4.46Å; I441-R445 WeakPolarHBondContact O-CB 3.37Å; I441-R445 VanDerWaalsContact O-CG 3.24Å; I441-R445 WeakPolarHBondContact O-CG 3.43Å; I441-R445 PolarHBondContact O-N 2.82Å; K442-R445 WeakPolarHBondContact O-CB 3.24Å; K442-R445 PolarHBondContact O-N 3.2Å; N443-R445 VanDerWaalsContact C-N 3.35Å; N443-R445 PolarHBondContact O-N 3.36Å; R445-G449 PolarHBondContact O-N 3.45Å
446E87.4Confident83Confident131 Ų131116.1 Ų116.161%0.61255%0.55SS*.Hα-helixtrans-69.3-45.2176.2-177.6161.1-156.200112.1K442 N443 R448 G449 H450K442-E446 PolarHBondContact O-N 3.29Å; N443-E446 PolarHBondContact O-N 3.31Å; E446-R448 PolarHBondContact O-N 2.66Å; E446-G449 CarbonylContact O-C 3.54Å; E446-G449 WeakPolarHBondContact O-CA 3.3Å; E446-G449 PolarHBondContact O-N 3.39Å; E446-H450 PolarHBondContact O-N 2.99Å
447V87.3Confident81.6Confident81 Ų81122.4 Ų122.449%0.49157%0.57SS.*Hα-helixtrans-58.7-46172.81720000110.9N443 G449 H450 L451N443-V447 WeakPolarHBondContact O-CG2 3.5Å; N443-V447 PolarHBondContact O-N 3.23Å; V447-G449 VanDerWaalsContact C-N 3.25Å; V447-G449 PolarHBondContact O-N 3.22Å; V447-H450 WeakPolarHBondContact O-CA 3.22Å; V447-H450 WeakPolarHBondContact O-CB 3.25Å; V447-H450 PolarHBondContact O-N 3.25Å; V447-L451 HydrophobicContact CG1-CD1 4.06Å; V447-L451 HydrophobicContact CG1-CG 4.42Å; V447-L451 WeakPolarHBondContact O-CG 3.42Å; V447-L451 PolarHBondContact O-N 3.43Å
448R87.2Confident79.7Confident158 Ų158125.8 Ų125.860%0.59658%0.583SS**Hα-helixtrans-59.5-36.7173.1-172.2-179.769.3168.92.4112L444 E446 K452L444-R448 VanDerWaalsContact O-CB 3.25Å; L444-R448 WeakPolarHBondContact O-CB 3.41Å; L444-R448 PolarHBondContact O-N 3.25Å; E446-R448 PolarHBondContact O-N 2.66Å; R448-K452 WeakPolarHBondContact O-CG 3.47Å; R448-K452 PolarHBondContact O-N 2.85Å
449G81.7Confident77.7Confident25 Ų25125.5 Ų125.526%0.25859%0.594SS.*Hα-helixtrans-69.5-30173.100000113.7R445 E446 V447 R453R445-G449 PolarHBondContact O-N 3.45Å; E446-G449 CarbonylContact O-C 3.54Å; E446-G449 WeakPolarHBondContact O-CA 3.3Å; E446-G449 PolarHBondContact O-N 3.39Å; V447-G449 VanDerWaalsContact C-N 3.25Å; V447-G449 PolarHBondContact O-N 3.22Å; G449-R453 WeakPolarHBondContact O-CG 3.29Å; G449-R453 PolarHBondContact O-N 2.93Å; G449-R453 PolarHBondContact O-NE 2.9Å
450H83.6Confident75.3Confident94 Ų94127.3 Ų127.344%0.43561%0.612SS.*Hα-helixtrans-70.9-50.8170.9-170.7112.6000110.7E446 V447 K452 R453 R454E446-H450 PolarHBondContact O-N 2.99Å; V447-H450 WeakPolarHBondContact O-CA 3.22Å; V447-H450 WeakPolarHBondContact O-CB 3.25Å; V447-H450 PolarHBondContact O-N 3.25Å; H450-K452 VanDerWaalsContact C-N 3.31Å; H450-K452 PolarHBondContact O-N 3.41Å; H450-R453 CarbonylContact O-C 3.55Å; H450-R453 WeakPolarHBondContact O-CA 3.5Å; H450-R453 PolarHBondContact O-N 3.09Å; H450-R454 WeakPolarHBondContact NE2-CD 3.26Å; H450-R454 PolarHBondContact NE2-NE 3.17Å; H450-R454 PolarHBondContact O-N 3.48Å
451L81.8Confident73.1Confident115 Ų115126.3 Ų126.360%0.60262%0.622SS**Hα-helixtrans-58.3-40.4178.9-67.7171000111.9V447 R453 R454 K455V447-L451 HydrophobicContact CG1-CD1 4.06Å; V447-L451 HydrophobicContact CG1-CG 4.42Å; V447-L451 WeakPolarHBondContact O-CG 3.42Å; V447-L451 PolarHBondContact O-N 3.43Å; L451-R453 VanDerWaalsContact C-N 3.3Å; L451-R453 PolarHBondContact O-N 1.95Å; L451-R454 CarbonylContact O-C 3.59Å; L451-R454 PolarHBondContact O-N 3.42Å; L451-K455 PolarHBondContact O-N 2.93Å
452K75.6Confident70.7Confident172 Ų172127 Ų12775%0.74863%0.634SS**Hα-helixtrans-63.4-30172-78.9-162.2173.6-160.50114.3R448 H450R448-K452 WeakPolarHBondContact O-CG 3.47Å; R448-K452 PolarHBondContact O-N 2.85Å; H450-K452 VanDerWaalsContact C-N 3.31Å; H450-K452 PolarHBondContact O-N 3.41Å
453R77.2Confident68.1Low186 Ų186131.5 Ų131.570%0.70265%0.654SS**Hα-helixtrans-85.8-17.7177.9-76.5177.8-71.5172.5-1.7113.5G449 H450 L451G449-R453 WeakPolarHBondContact O-CG 3.29Å; G449-R453 PolarHBondContact O-N 2.93Å; G449-R453 PolarHBondContact O-NE 2.9Å; H450-R453 CarbonylContact O-C 3.55Å; H450-R453 WeakPolarHBondContact O-CA 3.5Å; H450-R453 PolarHBondContact O-N 3.09Å; L451-R453 VanDerWaalsContact C-N 3.3Å; L451-R453 PolarHBondContact O-N 1.95Å
454R71.8Confident65.6Low190 Ų190136.6 Ų136.672%0.71767%0.674SS**SBendtrans-116.828175.5-69.6-153.8-176.5-106.96.3112.8H450 L451 P456H450-R454 WeakPolarHBondContact NE2-CD 3.26Å; H450-R454 PolarHBondContact NE2-NE 3.17Å; H450-R454 PolarHBondContact O-N 3.48Å; L451-R454 CarbonylContact O-C 3.59Å; L451-R454 PolarHBondContact O-N 3.42Å; R454-P456 VanDerWaalsContact O-CD 3.25Å; R454-P456 WeakPolarHBondContact O-CD 3.44Å
455K71.6Confident63Low135 Ų135136.2 Ų136.259%0.58768%0.681SS**PPolyproline II helixtrans-60.6121.6170.8-167.1-147.1169.3-167.90107.7L451 E458L451-K455 PolarHBondContact O-N 2.93Å; K455-E458 IonicContact NZ-OE1 2.92Å; K455-E458 PolarHBondContact NZ-OE1 3.08Å
456P66.1Low60.3Low104 Ų104139.6 Ų139.668%0.67570%0.696SS**PPolyproline II helixtrans-63.6148.4168.8-18.432.9000109.9R454R454-P456 VanDerWaalsContact O-CD 3.25Å; R454-P456 WeakPolarHBondContact O-CD 3.44Å
457E54.7Low57.6Low188 Ų188143.5 Ų143.588%0.87971%0.706SS**PPolyproline II helixtrans-79152164.1-62.1-163.3162.500109.8C459E457-C459 PolarHBondContact O-N 2.96Å
458E47.8Very low54.8Low154 Ų154146.5 Ų146.572%0.7272%0.72SS**PPolyproline II helixtrans-79119.8-165.7-77.3150.9-141.200111.6K455 S460K455-E458 IonicContact NZ-OE1 2.92Å; K455-E458 PolarHBondContact NZ-OE1 3.08Å; E458-S460 PolarHBondContact O-N 3.47Å; E458-S460 VanDerWaalsContact O-N 3.1Å
459C42.4Very low52.2Low120 Ų120146.8 Ų146.881%0.81173%0.725SS**  trans-76.696.3-179.7-170.30000110.6E457 C461E457-C459 PolarHBondContact O-N 2.96Å; C459-C461 PolarHBondContact O-N 3.45Å
460S37.9Very low50Low115 Ų115152.7 Ų152.780%0.80475%0.746SS**  trans-76.564.3178.449.50000112.5E458 S462E458-S460 PolarHBondContact O-N 3.47Å; E458-S460 VanDerWaalsContact O-N 3.1Å; S460-S462 VanDerWaalsContact C-N 3.28Å; S460-S462 PolarHBondContact O-N 2.99Å
461C41.6Very low47.5Very low118 Ų118157.9 Ų157.980%0.79777%0.767SS**  trans-77.171.1-179.5-161.70000112.3C459C459-C461 PolarHBondContact O-N 3.45Å
462S39.3Very low45Very low100 Ų100156 Ų15670%0.69978%0.776SS**  trans-16588.6170.645.40000114.9S460S460-S462 VanDerWaalsContact C-N 3.28Å; S460-S462 PolarHBondContact O-N 2.99Å
463K34.6Very low42.9Very low214 Ų214155 Ų15593%0.9378%0.784SS**  trans-173.3150.7132.2-101.5155-170.5179.30111.9
464Q32.3Very low40.9Very low192 Ų192155.8 Ų155.890%0.89779%0.793SS**  trans-81.2163.2-174.6-74.4150.1-69.100113.2
465S33.5Very low38.9Very low103 Ų103156.8 Ų156.872%0.7280%0.802SS**  trans-62143.717852.50000114.3
466Y30.4Very low36.9Very low236 Ų236158.6 Ų158.693%0.92581%0.813SS**  trans-146.6147.5142.9-106.3-78.6000110.5
467Y30.5Very low35.2Very low213 Ų213162.6 Ų162.684%0.83582%0.822SS**  trans-75146.1178.2-84-106.7000111.9
468N30.3Very low34.1Very low145 Ų145162.4 Ų162.478%0.77582%0.819SS**  -171.3174.5113.4-108.4-66.8000116.6
469K31.1Very low33.4Very low164 Ų164162.9 Ų162.971%0.71383%0.825SS**  trans-67.6158.4-162.9-65.3174174.8-175.70118.5
470E36Very low33.1Very low148 Ų148166.5 Ų166.569%0.69283%0.827SS**  trans43.3107.8137.7-64.3166.8-13800120.7
471K30.1Very low32.8Very low203 Ų203166.4 Ų166.488%0.88383%0.827SS**  -174.8145.6100.4-95.8157-172.2173.90110.2
472G31.1Very low32.7Very low77 Ų77169.2 Ų169.279%0.79483%0.828SS**  trans-99.3156.2-171.800000114.6
473V30Very low32.8Very low151 Ų151170.2 Ų170.292%0.91583%0.825SS**  trans-148.2148.9154.2143.80000108.5
474K35.6Very low33.3Very low202 Ų202167.4 Ų167.488%0.87881%0.814SS**  trans-72.8139.3-168.7-57.5168.4-176.81730113.4
475K31.1Very low34Very low210 Ų210162.7 Ų162.791%0.91380%0.8SS**  trans-148.4149.6145.4-135.8168.1-172.6173.10111.2
476Q29.1Very low34.4Very low173 Ų173166.7 Ų166.781%0.80881%0.805SS**PPolyproline II helixtrans-81.8122.9-170.4-66.4173.5-3100112.1
477E29.6Very low35.1Very low188 Ų188162.3 Ų162.388%0.87979%0.791SS**PPolyproline II helixtrans-82.7127.9149.5-67.6-160.5121.600109.1
478K31.9Very low35.7Very low184 Ų184157.5 Ų157.580%0.878%0.776SS**PPolyproline II helixtrans-98.6123163.9-82.7-173.2174-179.40108.4
479L32.4Very low36.5Very low165 Ų165152.9 Ų152.986%0.86476%0.758SS**PPolyproline II helixtrans-51.2141.4173.9-9069.1000111.1S481L479-S481 PolarHBondContact O-N 3.24Å; L479-S481 VanDerWaalsContact O-N 3.13Å
480K36.6Very low37.5Very low195 Ų195148 Ų14885%0.84875%0.749SS**  trans-66.5106.9167.6-67.5172.2-179169.20108.9H482K480-H482 PolarHBondContact O-N 2.91Å
481S32.2Very low38.2Very low114 Ų114147.5 Ų147.580%0.79775%0.746SS**  trans-69.4110.8166.158.30000109.1L479L479-S481 PolarHBondContact O-N 3.24Å; L479-S481 VanDerWaalsContact O-N 3.13Å
482H38.8Very low39.2Very low177 Ų177143.1 Ų143.182%0.81973%0.729SS**PPolyproline II helixtrans-57.3140.3171.6-82.4-117.8000110.6K480K480-H482 PolarHBondContact O-N 2.91Å
483L41.9Very low40.4Very low121 Ų121144 Ų14463%0.63472%0.719SS**PPolyproline II helixtrans-74137.4168.1-80.3159.5000109.1
484H44.8Very low41.6Very low154 Ų154140.6 Ų140.671%0.71370%0.695SS**PPolyproline II helixtrans-71132.4178.9-86.5-83.8000111.3F486 K487H484-F486 PolarHBondContact O-N 2.94Å; H484-K487 PolarHBondContact O-N 3.12Å
485P46.3Very low42.6Very low93 Ų93134 Ų13460%0.60468%0.675SS**Hα-helixtrans-52.4-31.1-174.2-31.835.9000116K487 E488 A489P485-K487 PolarHBondContact O-N 3.38Å; P485-E488 PolarHBondContact O-N 2.94Å; P485-A489 PolarHBondContact O-N 3.27Å; P485-A489 VanDerWaalsContact O-N 3.07Å
486F42.2Very low44.3Very low187 Ų187130 Ų13082%0.8266%0.657SS**Hα-helixtrans-63.8-20.3179.4-85.1-86000114.8H484 A490H484-F486 PolarHBondContact O-N 2.94Å; F486-A490 WeakPolarHBondContact O-CB 3.5Å; F486-A490 PolarHBondContact O-N 3.04Å
487K45.3Very low46.1Very low144 Ų144125.1 Ų125.163%0.62664%0.637SS**Hα-helixtrans-81.1-40.5174.7-98.6-177.8177.1174.90112.7H484 P485 A490 Q491H484-K487 PolarHBondContact O-N 3.12Å; P485-K487 PolarHBondContact O-N 3.38Å; K487-A490 PolarHBondContact O-N 3.07Å; K487-Q491 WeakPolarHBondContact O-CG 3.39Å; K487-Q491 PolarHBondContact O-N 2.91Å
488E43.5Very low47.7Very low113 Ų113121.4 Ų121.453%0.52862%0.619SS.*Hα-helixtrans-66.8-45.2177.8-67178143.700109.8P485 A490 Q491 E492P485-E488 PolarHBondContact O-N 2.94Å; E488-A490 VanDerWaalsContact C-N 3.3Å; E488-A490 PolarHBondContact O-N 3.29Å; E488-Q491 PolarHBondContact O-N 2.8Å; E488-E492 WeakPolarHBondContact O-CB 3.3Å; E488-E492 PolarHBondContact O-N 3.33Å
489A47.9Very low49.5Very low48 Ų48117.2 Ų117.240%0.39761%0.605SS.*Hα-helixtrans-56.4-40.7172.800000113P485 V493P485-A489 PolarHBondContact O-N 3.27Å; P485-A489 VanDerWaalsContact O-N 3.07Å; A489-V493 WeakPolarHBondContact O-CB 3.41Å; A489-V493 WeakPolarHBondContact O-CG2 3.46Å; A489-V493 PolarHBondContact O-N 2.84Å
490A50.7Low51.3Low62 Ų62115.2 Ų115.251%0.51259%0.59SS.*Hα-helixtrans-68.8-40177.800000112.9F486 K487 E488 D494F486-A490 WeakPolarHBondContact O-CB 3.5Å; F486-A490 PolarHBondContact O-N 3.04Å; K487-A490 PolarHBondContact O-N 3.07Å; E488-A490 VanDerWaalsContact C-N 3.3Å; E488-A490 PolarHBondContact O-N 3.29Å; A490-D494 PolarHBondContact O-N 3.34Å
491Q50.3Low53Low137 Ų137111.5 Ų111.564%0.6457%0.573SS**Hα-helixtrans-70.9-39.8175.6-69.4-173.4-78.800111.7K487 E488 D494 S495K487-Q491 WeakPolarHBondContact O-CG 3.39Å; K487-Q491 PolarHBondContact O-N 2.91Å; E488-Q491 PolarHBondContact O-N 2.8Å; Q491-D494 PolarHBondContact O-N 3.17Å; Q491-S495 VanDerWaalsContact O-CB 3.29Å; Q491-S495 WeakPolarHBondContact O-CB 3.36Å; Q491-S495 PolarHBondContact O-N 3.19Å; Q491-S495 PolarHBondContact O-OG 3.2Å; Q491-S495 VanDerWaalsContact O-OG 3.07Å
492E52.3Low54.8Low110 Ų110112.3 Ų112.351%0.51457%0.565SS.*Hα-helixtrans-63.1-46.6175-163.8-158.514900110.6E488 D494 S495 K496E488-E492 WeakPolarHBondContact O-CB 3.3Å; E488-E492 PolarHBondContact O-N 3.33Å; E492-D494 PolarHBondContact O-N 2.97Å; E492-S495 PolarHBondContact O-N 3.09Å; E492-K496 WeakPolarHBondContact O-CB 3.5Å; E492-K496 PolarHBondContact O-N 3.09Å; E492-K496 IonicContact OE1-NZ 2.69Å; E492-K496 PolarHBondContact OE1-NZ 2.86Å
493V55.3Low56.4Low96 Ų96107.3 Ų107.358%0.58254%0.544SS*.Hα-helixtrans-60.7-43.3178.4166.70000112A489 K496 L497A489-V493 WeakPolarHBondContact O-CB 3.41Å; A489-V493 WeakPolarHBondContact O-CG2 3.46Å; A489-V493 PolarHBondContact O-N 2.84Å; V493-K496 PolarHBondContact O-N 3.32Å; V493-L497 VanDerWaalsContact O-CB 3.27Å; V493-L497 WeakPolarHBondContact O-CB 3.01Å; V493-L497 PolarHBondContact O-N 3.13Å
494D56.2Low57.8Low80 Ų80104.2 Ų104.243%0.42853%0.528SS..Hα-helixtrans-72.6-37.3178-163.539.2000112.1A490 Q491 E492 K496 L497 Q498A490-D494 PolarHBondContact O-N 3.34Å; Q491-D494 PolarHBondContact O-N 3.17Å; E492-D494 PolarHBondContact O-N 2.97Å; D494-K496 VanDerWaalsContact C-N 3.35Å; D494-K496 PolarHBondContact O-N 3.43Å; D494-L497 PolarHBondContact O-N 3.01Å; D494-Q498 WeakPolarHBondContact O-CB 3.33Å; D494-Q498 VanDerWaalsContact O-CG 3.31Å; D494-Q498 WeakPolarHBondContact O-CG 3.24Å; D494-Q498 PolarHBondContact O-N 2.9Å; D494-Q498 PolarHBondContact OD2-NE2 2.97Å
495S57.2Low59Low64 Ų64106.7 Ų106.745%0.44853%0.531SS..Hα-helixtrans-61.5-40.4170.2-69.50000112.5Q491 E492 Q498 L499Q491-S495 VanDerWaalsContact O-CB 3.29Å; Q491-S495 WeakPolarHBondContact O-CB 3.36Å; Q491-S495 PolarHBondContact O-N 3.19Å; Q491-S495 PolarHBondContact O-OG 3.2Å; Q491-S495 VanDerWaalsContact O-OG 3.07Å; E492-S495 PolarHBondContact O-N 3.09Å; S495-Q498 PolarHBondContact O-N 3.12Å; S495-L499 WeakPolarHBondContact O-CB 3.46Å; S495-L499 PolarHBondContact O-N 3.29Å
496K65.1Low60Low124 Ų124109.8 Ų109.854%0.53953%0.531SS..Hα-helixtrans-70.7-33.4177.9-163169.7-161.2158.20111E492 V493 D494 F500E492-K496 WeakPolarHBondContact O-CB 3.5Å; E492-K496 PolarHBondContact O-N 3.09Å; E492-K496 IonicContact OE1-NZ 2.69Å; E492-K496 PolarHBondContact OE1-NZ 2.86Å; V493-K496 PolarHBondContact O-N 3.32Å; D494-K496 VanDerWaalsContact C-N 3.35Å; D494-K496 PolarHBondContact O-N 3.43Å; K496-F500 VanDerWaalsContact O-CB 3.23Å; K496-F500 WeakPolarHBondContact O-CB 3.46Å; K496-F500 PolarHBondContact O-N 3.18Å
497L66.8Low61.4Low72 Ų72108 Ų10838%0.37752%0.519SS..Hα-helixtrans-70.2-38.1170.4-178.661.6000112.3V493 D494 F500 K501V493-L497 VanDerWaalsContact O-CB 3.27Å; V493-L497 WeakPolarHBondContact O-CB 3.01Å; V493-L497 PolarHBondContact O-N 3.13Å; D494-L497 PolarHBondContact O-N 3.01Å; L497-F500 PolarHBondContact O-N 2.83Å; L497-K501 HydrophobicContact CG-CD 4.31Å; L497-K501 WeakPolarHBondContact O-CB 3.49Å; L497-K501 WeakPolarHBondContact O-CD 3.45Å; L497-K501 VanDerWaalsContact O-CG 3.26Å; L497-K501 WeakPolarHBondContact O-CG 3.37Å; L497-K501 PolarHBondContact O-N 2.79Å
498Q64.7Low62.6Low110 Ų110108.5 Ų108.551%0.51452%0.52SS..Hα-helixtrans-65.2-49.4172-72177.933.500110.8D494 S495 F500 K501 E502D494-Q498 WeakPolarHBondContact O-CB 3.33Å; D494-Q498 VanDerWaalsContact O-CG 3.31Å; D494-Q498 WeakPolarHBondContact O-CG 3.24Å; D494-Q498 PolarHBondContact O-N 2.9Å; D494-Q498 PolarHBondContact OD2-NE2 2.97Å; S495-Q498 PolarHBondContact O-N 3.12Å; Q498-F500 VanDerWaalsContact C-N 3.28Å; Q498-F500 PolarHBondContact O-N 3.47Å; Q498-K501 PolarHBondContact O-N 2.75Å; Q498-K501 VanDerWaalsContact O-N 3.12Å; Q498-E502 WeakPolarHBondContact O-CB 3.33Å; Q498-E502 PolarHBondContact O-N 3.3Å
499L68.7Low64Low95 Ų95109.1 Ų109.150%0.49752%0.521SS..Hα-helixtrans-56.9-36.9171.6-92159.3000112.7S495 N503S495-L499 WeakPolarHBondContact O-CB 3.46Å; S495-L499 PolarHBondContact O-N 3.29Å; L499-N503 WeakPolarHBondContact O-CB 3.41Å; L499-N503 VanDerWaalsContact O-CG 3.3Å; L499-N503 PolarHBondContact O-N 3.14Å; L499-N503 PolarHBondContact O-ND2 3.05Å
500F71.5Confident65Low124 Ų124110 Ų11054%0.54452%0.518SS..Hα-helixtrans-71.1-39.5175.6-172.2-109.6000112.1K496 L497 Q498 N504K496-F500 VanDerWaalsContact O-CB 3.23Å; K496-F500 WeakPolarHBondContact O-CB 3.46Å; K496-F500 PolarHBondContact O-N 3.18Å; L497-F500 PolarHBondContact O-N 2.83Å; Q498-F500 VanDerWaalsContact C-N 3.28Å; Q498-F500 PolarHBondContact O-N 3.47Å; F500-N504 VanDerWaalsContact CD1-ND2 3.32Å; F500-N504 WeakPolarHBondContact CD1-ND2 3.2Å; F500-N504 WeakPolarHBondContact CE1-ND2 3.36Å; F500-N504 VanDerWaalsContact CZ-ND2 3.28Å; F500-N504 WeakPolarHBondContact CZ-ND2 3.48Å; F500-N504 VanDerWaalsContact O-CB 3.23Å; F500-N504 WeakPolarHBondContact O-CB 3.19Å; F500-N504 VanDerWaalsContact O-CG 3.28Å; F500-N504 PolarHBondContact O-N 2.88Å; F500-N504 PolarHBondContact O-ND2 3.49Å
501K71.3Confident66Low117 Ų117116.2 Ų116.251%0.50953%0.528SS..Hα-helixtrans-64.9-40.1173-73.6164-178.8167.60111.6L497 Q498 N504 R505L497-K501 HydrophobicContact CG-CD 4.31Å; L497-K501 WeakPolarHBondContact O-CB 3.49Å; L497-K501 WeakPolarHBondContact O-CD 3.45Å; L497-K501 VanDerWaalsContact O-CG 3.26Å; L497-K501 WeakPolarHBondContact O-CG 3.37Å; L497-K501 PolarHBondContact O-N 2.79Å; Q498-K501 PolarHBondContact O-N 2.75Å; Q498-K501 VanDerWaalsContact O-N 3.12Å; K501-N504 PolarHBondContact O-N 2.96Å; K501-R505 PolarHBondContact O-N 3.46Å
502E69.6Low66.6Low131 Ų131116.8 Ų116.861%0.61253%0.528SS*.Hα-helixtrans-71.1-47.1177.7-175161-139.900111.9Q498 N504 R505 R506Q498-E502 WeakPolarHBondContact O-CB 3.33Å; Q498-E502 PolarHBondContact O-N 3.3Å; E502-N504 PolarHBondContact O-N 3.47Å; E502-R505 CarbonylContact O-C 3.54Å; E502-R505 WeakPolarHBondContact O-CA 3.27Å; E502-R505 WeakPolarHBondContact O-CB 3.37Å; E502-R505 PolarHBondContact O-N 2.77Å; E502-R505 VanDerWaalsContact O-N 3.07Å; E502-R506 WeakPolarHBondContact O-CB 3.36Å; E502-R506 PolarHBondContact O-N 2.84Å
503N73.1Confident67.1Low72 Ų72114.8 Ų114.839%0.38552%0.519SS..Hα-helixtrans-62.3-30.9172.7-78-46.3000112.3L499 R507L499-N503 WeakPolarHBondContact O-CB 3.41Å; L499-N503 VanDerWaalsContact O-CG 3.3Å; L499-N503 PolarHBondContact O-N 3.14Å; L499-N503 PolarHBondContact O-ND2 3.05Å; N503-R507 WeakPolarHBondContact O-CB 3.23Å; N503-R507 VanDerWaalsContact O-CG 3.24Å; N503-R507 WeakPolarHBondContact O-CG 3.5Å; N503-R507 PolarHBondContact O-N 3.48Å
504N71.6Confident67.5Low56 Ų56116.7 Ų116.730%0.29952%0.519SS..Hα-helixtrans-75.1-33171.5-78.9-47.5000113.1F500 K501 E502 K508F500-N504 VanDerWaalsContact CD1-ND2 3.32Å; F500-N504 WeakPolarHBondContact CD1-ND2 3.2Å; F500-N504 WeakPolarHBondContact CE1-ND2 3.36Å; F500-N504 VanDerWaalsContact CZ-ND2 3.28Å; F500-N504 WeakPolarHBondContact CZ-ND2 3.48Å; F500-N504 VanDerWaalsContact O-CB 3.23Å; F500-N504 WeakPolarHBondContact O-CB 3.19Å; F500-N504 VanDerWaalsContact O-CG 3.28Å; F500-N504 PolarHBondContact O-N 2.88Å; F500-N504 PolarHBondContact O-ND2 3.49Å; K501-N504 PolarHBondContact O-N 2.96Å; E502-N504 PolarHBondContact O-N 3.47Å; N504-K508 VanDerWaalsContact O-CB 3.27Å; N504-K508 WeakPolarHBondContact O-CB 3.42Å; N504-K508 VanDerWaalsContact O-CG 3.28Å; N504-K508 WeakPolarHBondContact O-CG 3.41Å; N504-K508 PolarHBondContact O-N 3.26Å
505R69.3Low67.6Low206 Ų206122.5 Ų122.578%0.77754%0.535SS*.Hα-helixtrans-63.5-45.9167.6-82.5179.5166.4179.8-4.1111K501 E502 K508 K509K501-R505 PolarHBondContact O-N 3.46Å; E502-R505 CarbonylContact O-C 3.54Å; E502-R505 WeakPolarHBondContact O-CA 3.27Å; E502-R505 WeakPolarHBondContact O-CB 3.37Å; E502-R505 PolarHBondContact O-N 2.77Å; E502-R505 VanDerWaalsContact O-N 3.07Å; R505-K508 PolarHBondContact O-N 3.45Å; R505-K509 PolarHBondContact O-N 3.43Å
506R67.9Low67.5Low157 Ų157127.8 Ų127.859%0.59255%0.545SS*.Hα-helixtrans-61.8-51.3177-177174.7176157.34.3111.5E502 K508 K509 E510E502-R506 WeakPolarHBondContact O-CB 3.36Å; E502-R506 PolarHBondContact O-N 2.84Å; R506-K508 VanDerWaalsContact C-N 3.3Å; R506-K508 PolarHBondContact O-N 3.17Å; R506-K509 CarbonylContact O-C 3.42Å; R506-K509 WeakPolarHBondContact O-CA 3.41Å; R506-K509 WeakPolarHBondContact O-CB 3.44Å; R506-K509 PolarHBondContact O-N 3.15Å; R506-E510 HydrophobicContact CG-CG 4.41Å; R506-E510 VanDerWaalsContact CG-OE1 3.23Å; R506-E510 WeakPolarHBondContact CG-OE1 3.01Å; R506-E510 IonicContact CZ-OE1 3.66Å; R506-E510 IonicContact NE-OE1 1.95Å; R506-E510 PolarHBondContact NE-OE1 3.44Å; R506-E510 IonicContact NH2-OE1 3.75Å; R506-E510 WeakPolarHBondContact O-CB 3.49Å; R506-E510 WeakPolarHBondContact O-CG 3.28Å; R506-E510 PolarHBondContact O-N 3.34Å
507R72.1Confident67Low151 Ų151127.3 Ų127.357%0.5755%0.545SS*.Hα-helixtrans-60.2-34172.6-75.9173.4167.5-171.3-4.7113N503 R511N503-R507 WeakPolarHBondContact O-CB 3.23Å; N503-R507 VanDerWaalsContact O-CG 3.24Å; N503-R507 WeakPolarHBondContact O-CG 3.5Å; N503-R507 PolarHBondContact O-N 3.48Å; R507-R511 VanDerWaalsContact O-CB 3.23Å; R507-R511 WeakPolarHBondContact O-CB 3.4Å; R507-R511 WeakPolarHBondContact O-CG 3.42Å; R507-R511 PolarHBondContact O-N 3.24Å
508K69.4Low66.5Low153 Ų153134.8 Ų134.867%0.66557%0.568SS**Hα-helixtrans-69-36.9171.3-80.9-176.5178.4-171.90112.1N504 R505 R506 K512N504-K508 VanDerWaalsContact O-CB 3.27Å; N504-K508 WeakPolarHBondContact O-CB 3.42Å; N504-K508 VanDerWaalsContact O-CG 3.28Å; N504-K508 WeakPolarHBondContact O-CG 3.41Å; N504-K508 PolarHBondContact O-N 3.26Å; R505-K508 PolarHBondContact O-N 3.45Å; R506-K508 VanDerWaalsContact C-N 3.3Å; R506-K508 PolarHBondContact O-N 3.17Å; K508-K512 PolarHBondContact O-N 3Å; K508-K512 VanDerWaalsContact O-N 3.12Å
509K72.4Confident65.8Low126 Ų126137.4 Ų137.455%0.54858%0.578SS.*Hα-helixtrans-63.8-56.4171.4-166.7-164173.7-128.30110R505 R506 R511 K512 E513R505-K509 PolarHBondContact O-N 3.43Å; R506-K509 CarbonylContact O-C 3.42Å; R506-K509 WeakPolarHBondContact O-CA 3.41Å; R506-K509 WeakPolarHBondContact O-CB 3.44Å; R506-K509 PolarHBondContact O-N 3.15Å; K509-R511 VanDerWaalsContact C-N 3.26Å; K509-R511 PolarHBondContact O-N 3.1Å; K509-K512 CarbonylContact O-C 3.53Å; K509-K512 WeakPolarHBondContact O-CA 3.02Å; K509-K512 WeakPolarHBondContact O-CB 3.39Å; K509-K512 PolarHBondContact O-N 3.48Å; K509-E513 WeakPolarHBondContact CE-OE1 3.5Å; K509-E513 IonicContact NZ-OE1 3.74Å; K509-E513 PolarHBondContact NZ-OE1 3.26Å; K509-E513 IonicContact NZ-OE2 3.9Å; K509-E513 PolarHBondContact NZ-OE2 2.85Å; K509-E513 VanDerWaalsContact NZ-OE2 3.16Å; K509-E513 WeakPolarHBondContact O-CB 3.22Å; K509-E513 PolarHBondContact O-N 2.87Å
510E68.8Low64.7Low68 Ų68135 Ų13532%0.31858%0.576SS.*Hα-helixtrans-56.7-33.9178.2-68.5165.2178.300112.7R506 K514R506-E510 HydrophobicContact CG-CG 4.41Å; R506-E510 VanDerWaalsContact CG-OE1 3.23Å; R506-E510 WeakPolarHBondContact CG-OE1 3.01Å; R506-E510 IonicContact CZ-OE1 3.66Å; R506-E510 IonicContact NE-OE1 1.95Å; R506-E510 PolarHBondContact NE-OE1 3.44Å; R506-E510 IonicContact NH2-OE1 3.75Å; R506-E510 WeakPolarHBondContact O-CB 3.49Å; R506-E510 WeakPolarHBondContact O-CG 3.28Å; R506-E510 PolarHBondContact O-N 3.34Å; E510-K514 VanDerWaalsContact O-CB 3.28Å; E510-K514 WeakPolarHBondContact O-CB 3.23Å; E510-K514 WeakPolarHBondContact O-CG 3.25Å; E510-K514 PolarHBondContact O-N 2.94Å
511R73.3Confident63.7Low191 Ų191135.7 Ų135.772%0.72158%0.581SS**Hα-helixtrans-70.8-34.9171.7-78.6175.4178.2-165.8-0.7113.1R507 K509 R515R507-R511 VanDerWaalsContact O-CB 3.23Å; R507-R511 WeakPolarHBondContact O-CB 3.4Å; R507-R511 WeakPolarHBondContact O-CG 3.42Å; R507-R511 PolarHBondContact O-N 3.24Å; K509-R511 VanDerWaalsContact C-N 3.26Å; K509-R511 PolarHBondContact O-N 3.1Å; R511-R515 WeakPolarHBondContact O-CB 3.34Å; R511-R515 WeakPolarHBondContact O-CG 3.4Å; R511-R515 PolarHBondContact O-N 3.1Å
512K62.9Low63.1Low150 Ų150138.6 Ų138.665%0.65260%0.596SS**Hα-helixtrans-70.5-39.4170.2-73.5-168.7175.4-164.80111.5K508 K509 R515 R516K508-K512 PolarHBondContact O-N 3Å; K508-K512 VanDerWaalsContact O-N 3.12Å; K509-K512 CarbonylContact O-C 3.53Å; K509-K512 WeakPolarHBondContact O-CA 3.02Å; K509-K512 WeakPolarHBondContact O-CB 3.39Å; K509-K512 PolarHBondContact O-N 3.48Å; K512-R515 PolarHBondContact O-N 2.94Å; K512-R516 WeakPolarHBondContact O-CG 3.37Å; K512-R516 PolarHBondContact O-N 3.43Å
513E60.9Low63.2Low68 Ų68133.7 Ų133.732%0.31858%0.576SS.*Hα-helixtrans-64.2-49.7178.6-141.2141.7-137.800110.3K509 R515 R516 Q517K509-E513 WeakPolarHBondContact CE-OE1 3.5Å; K509-E513 IonicContact NZ-OE1 3.74Å; K509-E513 PolarHBondContact NZ-OE1 3.26Å; K509-E513 IonicContact NZ-OE2 3.9Å; K509-E513 PolarHBondContact NZ-OE2 2.85Å; K509-E513 VanDerWaalsContact NZ-OE2 3.16Å; K509-E513 WeakPolarHBondContact O-CB 3.22Å; K509-E513 PolarHBondContact O-N 2.87Å; E513-R515 VanDerWaalsContact C-N 3.32Å; E513-R515 PolarHBondContact O-N 3.39Å; E513-R516 WeakPolarHBondContact O-CB 3.39Å; E513-R516 PolarHBondContact O-N 2.95Å; E513-R516 VanDerWaalsContact O-N 3.12Å; E513-Q517 WeakPolarHBondContact O-CG 3.4Å; E513-Q517 PolarHBondContact O-N 3.28Å
514K64.6Low63Low135 Ų135134 Ų13459%0.58758%0.584SS**Hα-helixtrans-66.9-26.5172.5-71.3179.5176.2-176.50113.8E510 R518E510-K514 VanDerWaalsContact O-CB 3.28Å; E510-K514 WeakPolarHBondContact O-CB 3.23Å; E510-K514 WeakPolarHBondContact O-CG 3.25Å; E510-K514 PolarHBondContact O-N 2.94Å; K514-R518 VanDerWaalsContact O-CB 3.25Å; K514-R518 WeakPolarHBondContact O-CB 3.42Å; K514-R518 VanDerWaalsContact O-CG 3.23Å; K514-R518 WeakPolarHBondContact O-CG 3.33Å; K514-R518 PolarHBondContact O-N 3.36Å
515R59Low63.1Low203 Ų203135.8 Ų135.877%0.76659%0.593SS**Hα-helixtrans-71.4-33.4169.7-87.5-175.1172-166.5-2.8112.5R511 K512 E513 K519R511-R515 WeakPolarHBondContact O-CB 3.34Å; R511-R515 WeakPolarHBondContact O-CG 3.4Å; R511-R515 PolarHBondContact O-N 3.1Å; K512-R515 PolarHBondContact O-N 2.94Å; E513-R515 VanDerWaalsContact C-N 3.32Å; E513-R515 PolarHBondContact O-N 3.39Å; R515-K519 PolarHBondContact O-N 3.45Å
516R55.4Low63.3Low175 Ų175131.9 Ų131.966%0.6659%0.594SS**Hα-helixtrans-67.9-53.2171.6-71.9167.6170.2-172.5-9.4110.7K512 E513 R518 K519 G520K512-R516 WeakPolarHBondContact O-CG 3.37Å; K512-R516 PolarHBondContact O-N 3.43Å; E513-R516 WeakPolarHBondContact O-CB 3.39Å; E513-R516 PolarHBondContact O-N 2.95Å; E513-R516 VanDerWaalsContact O-N 3.12Å; R516-R518 PolarHBondContact O-N 3.2Å; R516-K519 PolarHBondContact O-N 3.28Å; R516-G520 PolarHBondContact O-N 3.36Å
517Q54.3Low63.6Low114 Ų114126.7 Ų126.753%0.53359%0.589SS.*Hα-helixtrans-56.9-35.5177.8-69.3169.9-19.900112.9E513E513-Q517 WeakPolarHBondContact O-CG 3.4Å; E513-Q517 PolarHBondContact O-N 3.28Å
518R56Low64.1Low228 Ų228120.7 Ų120.786%0.8657%0.568SS**THydrogen-bonded Turntrans-76.2-13.8174.6-77.7179.7173.9-160.1-3115.5K514 R516K514-R518 VanDerWaalsContact O-CB 3.25Å; K514-R518 WeakPolarHBondContact O-CB 3.42Å; K514-R518 VanDerWaalsContact O-CG 3.23Å; K514-R518 WeakPolarHBondContact O-CG 3.33Å; K514-R518 PolarHBondContact O-N 3.36Å; R516-R518 PolarHBondContact O-N 3.2Å
519K48.8Very low64.8Low165 Ų165115.3 Ų115.372%0.71755%0.548SS*.THydrogen-bonded Turntrans-101.2-0.8175.1-103-151171.1-157.60113.3R515 R516 D534R515-K519 PolarHBondContact O-N 3.45Å; R516-K519 PolarHBondContact O-N 3.28Å; K519-D534 IonicContact NZ-OD2 2.75Å
520G46.9Very low65.5Low44 Ų44110.8 Ų110.845%0.45453%0.532SS..  trans81145-168.200000112R516 E522R516-G520 PolarHBondContact O-N 3.36Å; G520-E522 PolarHBondContact O-N 3.5Å
521E50.6Low66.2Low139 Ų139113 Ų11365%0.6554%0.541SS*.SBendtrans-88.637.9-178.5-61.3-169.8147.700112.3C523E521-C523 VanDerWaalsContact C-N 3.34Å; E521-C523 PolarHBondContact O-N 3.15Å
522E58.8Low66.8Low178 Ų178107.7 Ų107.783%0.83253%0.53SS*.  trans-79.2-14.7-171.8-164.7156.9-125.700113.6G520G520-E522 PolarHBondContact O-N 3.5Å
523C71.4Confident68Low28 Ų28101 Ų10119%0.18950%0.501CS..SBendtrans-129.663.8-179.5-170.40000113.3E521 F531 T532 C550E521-C523 VanDerWaalsContact C-N 3.34Å; E521-C523 PolarHBondContact O-N 3.15Å; C523-F531 PolarHBondContact SG-O 3.45Å; C523-F531 VanDerWaalsContact SG-O 3.37Å; C523-T532 WeakPolarHBondContact CB-OG1 3.5Å; C523-T532 PolarHBondContact SG-OG1 3.39Å; C523-C550 WeakPolarHBondContact CA-SG 3.26Å; C523-C550 HydrophobicContact CB-CB 3.63Å; C523-C550 WeakPolarHBondContact CB-SG 3.27Å; C523-C550 VanDerWaalsContact SG-CA 3.56Å; C523-C550 WeakPolarHBondContact SG-CB 3.33Å; C523-C550 CovalentContact SG-SG 2.04Å; C523-C550 PolarHBondContact SG-SG 3.02Å
524S68.8Low69.2Low78 Ų78100.1 Ų100.155%0.54550%0.498SS..  trans-152.5102.4169.651.80000113
525L73.9Confident70.2Confident95 Ų9597.1 Ų97.150%0.49749%0.489SS..  trans-83.3137.6166.9-66.5-180000110.7G527 L528 C530 C552L525-G527 PolarHBondContact O-N 2.84Å; L525-L528 HydrophobicContact CB-CB 4.28Å; L525-L528 HydrophobicContact CB-CD1 4.01Å; L525-L528 HydrophobicContact CD1-CD1 3.9Å; L525-L528 PolarHBondContact O-N 2.88Å; L525-C530 PolarHBondContact N-SG 2.89Å; L525-C530 VanDerWaalsContact N-SG 3.45Å; L525-C552 HydrophobicContact CD1-CB 4.01Å
526P71.7Confident71.4Confident124 Ų12493.9 Ų93.981%0.80549%0.487SS*.THydrogen-bonded Turntrans-55.8130.7177.9-26.835.4000112.8L528P526-L528 PolarHBondContact O-N 2.04Å
527G75.7Confident72.7Confident47 Ų4787.5 Ų87.549%0.48546%0.464SS..THydrogen-bonded Turntrans78.5-14.3177.400000116.1L525 S555L525-G527 PolarHBondContact O-N 2.84Å; G527-S555 WeakPolarHBondContact O-CB 3.43Å; G527-S555 PolarHBondContact O-OG 2.79Å
528L83.1Confident74.4Confident26 Ų2682.3 Ų82.314%0.13644%0.44CS..SBendtrans-96.9154.9176.8-67.7170000112W43 I44 L525 P526 C552 S554W43-L528 HydrophobicContact CH2-CD2 3.68Å; W43-L528 HydrophobicContact CH2-CG 4.29Å; W43-L528 HydrophobicContact CZ3-CD2 3.79Å; W43-L528 HydrophobicContact CZ3-CG 4.17Å; I44-L528 HydrophobicContact CD1-CD2 4.2Å; I44-L528 HydrophobicContact CG1-CD2 4.1Å; I44-L528 HydrophobicContact CG2-CD2 4.04Å; L525-L528 HydrophobicContact CB-CB 4.28Å; L525-L528 HydrophobicContact CB-CD1 4.01Å; L525-L528 HydrophobicContact CD1-CD1 3.9Å; L525-L528 PolarHBondContact O-N 2.88Å; P526-L528 PolarHBondContact O-N 2.04Å; L528-C552 HydrophobicContact CB-CB 4.24Å; L528-C552 HydrophobicContact CD1-CB 4.06Å; L528-S554 WeakPolarHBondContact CA-O 3.46Å; L528-S554 WeakPolarHBondContact CD2-O 3.1Å
529T84.2Confident75.8Confident40 Ų4079.3 Ų79.325%0.24544%0.435CS..EExtended strand (participates in β ladder)trans-98.2106.9168.533.40000109.3S554T529-S554 PolarHBondContact N-O 3.37Å; T529-S554 PolarHBondContact OG1-O 2.94Å; T529-S554 PolarHBondContact OG1-OG 3Å
530C85.8Confident77.5Confident30 Ų3073.1 Ų73.120%0.20341%0.412CS..EExtended strand (participates in β ladder)trans-103.8150.6-177.6-52.10000112.6L525 A551 C552L525-C530 PolarHBondContact N-SG 2.89Å; L525-C530 VanDerWaalsContact N-SG 3.45Å; C530-A551 CarbonylContact C-O 3.59Å; C530-A551 VanDerWaalsContact CA-O 3.27Å; C530-A551 WeakPolarHBondContact CA-O 3.47Å; C530-C552 HydrophobicContact CB-CB 4.05Å; C530-C552 WeakPolarHBondContact CB-SG 3.47Å; C530-C552 WeakPolarHBondContact SG-CB 3.44Å; C530-C552 CovalentContact SG-SG 2.04Å; C530-C552 PolarHBondContact SG-SG 3.44Å
531F84.4Confident79Confident116 Ų11673.3 Ų73.351%0.50941%0.409SS..EExtended strand (participates in β ladder)trans-126.5133.6177.3-57.3-86.1000109.5C523 A551C523-F531 PolarHBondContact SG-O 3.45Å; C523-F531 VanDerWaalsContact SG-O 3.37Å; F531-A551 PolarHBondContact N-O 2.04Å; F531-A551 PolarHBondContact O-N 3.46Å
532T86.1Confident80.6Confident79 Ų7968.5 Ų68.549%0.48539%0.39SS..EExtended strand (participates in β ladder)trans-88.6130.4170.5-46.90000108.5C523 F549C523-T532 WeakPolarHBondContact CB-OG1 3.5Å; C523-T532 PolarHBondContact SG-OG1 3.39Å; T532-F549 WeakPolarHBondContact CA-O 3.3Å
533H86.7Confident81.9Confident8 Ų866 Ų664%0.03738%0.376CS..EExtended strand (participates in β ladder)trans-102.3140.4164.2-68.2-71.2000108.1F58 H537 S548 F549F58-H533 HydrophobicContact CE2-CB 4.35Å; F58-H533 AromaticContact CZ-CE1 3.76Å; F58-H533 AromaticContact CZ-CG 3.8Å; F58-H533 AromaticContact CZ-ND1 3.58Å; H533-H537 AromaticContact CE1-CE1 3.69Å; H533-H537 AromaticContact CE1-ND1 3.62Å; H533-H537 AromaticContact ND1-CE1 3.84Å; H533-H537 AromaticContact ND1-CG 3.52Å; H533-H537 AromaticContact ND1-ND1 3Å; H533-H537 PolarHBondContact ND1-ND1 2.95Å; H533-S548 CarbonylContact O-C 3.4Å; H533-S548 WeakPolarHBondContact O-CA 3.39Å; H533-S548 VanDerWaalsContact O-CB 3.27Å; H533-S548 WeakPolarHBondContact O-CB 3.27Å; H533-F549 HydrophobicContact CB-CD1 4.01Å; H533-F549 HydrophobicContact CB-CE1 3.53Å; H533-F549 HydrophobicContact CB-CE2 4.33Å; H533-F549 HydrophobicContact CB-CZ 3.69Å; H533-F549 AromaticContact CD2-CE2 3.78Å; H533-F549 AromaticContact CD2-CZ 3.6Å; H533-F549 AromaticContact CG-CZ 3.8Å; H533-F549 PolarHBondContact N-O 2.98Å; H533-F549 PolarHBondContact O-N 3.27Å
534D86.3Confident82.8Confident51 Ų5164.8 Ų64.827%0.27337%0.368SS..  trans-136175.3176.259.739000110K519 N536 H537K519-D534 IonicContact NZ-OD2 2.75Å; D534-N536 PolarHBondContact O-N 2.98Å; D534-N536 PolarHBondContact OD1-N 3.17Å; D534-H537 VanDerWaalsContact O-CB 3.26Å; D534-H537 WeakPolarHBondContact O-CB 3.48Å; D534-H537 PolarHBondContact O-N 2.86Å
535N86.6Confident83.8Confident71 Ų7166.7 Ų66.738%0.3837%0.372SS..THydrogen-bonded Turntrans-60.3-14.2-174.3-69.612.2000113.6W544 G547N535-W544 VanDerWaalsContact CA-O 3.26Å; N535-W544 WeakPolarHBondContact CA-O 3.41Å; N535-W544 VanDerWaalsContact CB-O 3.28Å; N535-W544 WeakPolarHBondContact CB-O 3.44Å; N535-G547 WeakPolarHBondContact OD1-CA 3.31Å; N535-G547 PolarHBondContact OD1-N 2.84Å; N535-G547 VanDerWaalsContact OD1-N 3.1Å
536N83Confident84.4Confident136 Ų13666.3 Ų66.373%0.72737%0.37SS*.THydrogen-bonded Turntrans-96.214.9179.5-57.9-3.7000112.3D534 W538D534-N536 PolarHBondContact O-N 2.98Å; D534-N536 PolarHBondContact OD1-N 3.17Å; N536-W538 VanDerWaalsContact C-N 3.33Å; N536-W538 PolarHBondContact O-N 2.79Å
537H83.9Confident85.2Confident41 Ų4161.5 Ų61.519%0.1934%0.343CS..SBendtrans-68.1-26-177.6-176.773000114.1E12 F58 K112 H533 D534E12-H537 IonicContact OE1-NE2 3.03Å; E12-H537 IonicContact OE2-CE1 3.11Å; E12-H537 IonicContact OE2-NE2 2.64Å; E12-H537 PolarHBondContact OE2-NE2 2.98Å; F58-H537 AromaticContact CE2-CD2 3.81Å; F58-H537 AromaticContact CZ-CD2 3.94Å; K112-H537 PolarHBondContact NZ-CE1 2.8Å; K112-H537 VanDerWaalsContact NZ-CE1 3.31Å; K112-H537 PolarHBondContact NZ-NE2 2.84Å; H533-H537 AromaticContact CE1-CE1 3.69Å; H533-H537 AromaticContact CE1-ND1 3.62Å; H533-H537 AromaticContact ND1-CE1 3.84Å; H533-H537 AromaticContact ND1-CG 3.52Å; H533-H537 AromaticContact ND1-ND1 3Å; H533-H537 PolarHBondContact ND1-ND1 2.95Å; D534-H537 VanDerWaalsContact O-CB 3.26Å; D534-H537 WeakPolarHBondContact O-CB 3.48Å; D534-H537 PolarHBondContact O-N 2.86Å
538W89.3Confident85.8Confident4 Ų463 Ų632%0.01535%0.347CS..  trans-128.9136.1172.6-64.7-55000110.5E12 F58 I61 L62 K65 N536 W544E12-W538 PolarHBondContact OE2-NE1 3.15Å; E12-W538 VanDerWaalsContact OE2-NE1 3.09Å; F58-W538 AromaticContact CD2-CH2 3.66Å; F58-W538 HydrophobicContact CD2-CH2 3.66Å; F58-W538 HydrophobicContact CD2-CZ2 4.45Å; F58-W538 HydrophobicContact CD2-CZ3 4.17Å; F58-W538 AromaticContact CE2-CH2 3.48Å; F58-W538 HydrophobicContact CE2-CH2 3.48Å; F58-W538 VanDerWaalsContact CE2-CH2 3.48Å; F58-W538 AromaticContact CE2-CZ2 3.85Å; F58-W538 HydrophobicContact CE2-CZ2 3.85Å; F58-W538 HydrophobicContact CE2-CZ3 4.11Å; F58-W538 HydrophobicContact CG-CH2 4.44Å; F58-W538 HydrophobicContact CZ-CH2 4.15Å; F58-W538 HydrophobicContact CZ-CZ2 4.13Å; I61-W538 HydrophobicContact CB-CH2 3.91Å; I61-W538 HydrophobicContact CB-CZ3 3.91Å; I61-W538 HydrophobicContact CG2-CE3 3.94Å; I61-W538 HydrophobicContact CG2-CH2 3.62Å; I61-W538 HydrophobicContact CG2-CZ2 4.42Å; I61-W538 HydrophobicContact CG2-CZ3 3.33Å; L62-W538 HydrophobicContact CB-CH2 4.37Å; L62-W538 HydrophobicContact CB-CZ2 4.08Å; L62-W538 HydrophobicContact CD1-CZ2 4.13Å; K65-W538 HydrophobicContact CG-CD2 4.15Å; K65-W538 HydrophobicContact CG-CZ2 4.19Å; N536-W538 VanDerWaalsContact C-N 3.33Å; N536-W538 PolarHBondContact O-N 2.79Å; W538-W544 HydrophobicContact CE3-CB 3.98Å; W538-W544 HydrophobicContact CZ3-CB 4.15Å; W538-W544 HydrophobicContact CZ3-CD2 4.47Å; W538-W544 AromaticContact CZ3-CE3 3.98Å; W538-W544 HydrophobicContact CZ3-CE3 3.98Å
539Q85.9Confident86.1Confident165 Ų16562.6 Ų62.677%0.77134%0.344SS*.SBendtrans-94.1-7.5179.2-59.6-175.3-4.800113.2D13 F543D13-Q539 VanDerWaalsContact CG-N 3.26Å; D13-Q539 PolarHBondContact OD1-N 2.96Å; D13-Q539 PolarHBondContact OD2-N 3.08Å; Q539-F543 WeakPolarHBondContact O-CE1 3.23Å
540T84.1Confident86.3Confident35 Ų3562.5 Ų62.522%0.21534%0.344CS..SBendtrans-115.8157.4178.859.70000111.3D13 K65 P542D13-T540 HydrophobicContact CB-CG2 4.02Å; D13-T540 WeakPolarHBondContact OD1-CB 3.4Å; D13-T540 PolarHBondContact OD1-N 3.21Å; D13-T540 PolarHBondContact OD1-OG1 2.9Å; K65-T540 VanDerWaalsContact NZ-C 3.31Å; K65-T540 PolarHBondContact NZ-O 3.42Å; K65-T540 PolarHBondContact NZ-OG1 2.7Å; T540-P542 CarbonylContact O-C 3.6Å
541A79.7Confident86.4Confident49 Ų4961.2 Ų61.241%0.40534%0.336SS..SBendtrans-66.6148.3172.700000111.8K65 F543K65-A541 PolarHBondContact NZ-O 3.11Å; A541-F543 HydrophobicContact CB-CD2 4.45Å; A541-F543 HydrophobicContact CB-CE2 4.15Å
542P83.3Confident86.5Confident38 Ų3856.7 Ų56.725%0.24732%0.318CS..SBendcis-66.2137.5-13.530.3-36.2000111.6I61 K65 T540I61-P542 HydrophobicContact CG2-CG 3.81Å; K65-P542 WeakPolarHBondContact CE-O 3.5Å; K65-P542 PolarHBondContact NZ-O 3.31Å; T540-P542 CarbonylContact O-C 3.6Å
543F86.2Confident86.4Confident124 Ų12453.2 Ų53.254%0.54430%0.297SS..PPolyproline II helixtrans-81.2159.3176.7-59.5-76.7000111.3Q539 A541Q539-F543 WeakPolarHBondContact O-CE1 3.23Å; A541-F543 HydrophobicContact CB-CD2 4.45Å; A541-F543 HydrophobicContact CB-CE2 4.15Å
544W90Very high86.2Confident4 Ų453.4 Ų53.42%0.01530%0.299CS..PPolyproline II helixtrans-88.9117.2173.5-174.2-112.1000110.9I54 F58 I61 N535 W538 L546 G547 F549I54-W544 HydrophobicContact CD1-CZ2 4.03Å; I54-W544 HydrophobicContact CG1-CH2 3.9Å; I54-W544 HydrophobicContact CG1-CZ2 3.53Å; I54-W544 WeakPolarHBondContact O-CH2 3.44Å; F58-W544 HydrophobicContact CB-CH2 3.57Å; F58-W544 HydrophobicContact CB-CZ2 4.15Å; F58-W544 HydrophobicContact CB-CZ3 3.87Å; F58-W544 HydrophobicContact CD2-CD2 4.1Å; F58-W544 HydrophobicContact CD2-CE3 4.04Å; F58-W544 HydrophobicContact CD2-CH2 4.15Å; F58-W544 HydrophobicContact CD2-CZ2 4.19Å; F58-W544 HydrophobicContact CD2-CZ3 4.07Å; F58-W544 HydrophobicContact CG-CH2 4.37Å; F58-W544 HydrophobicContact CG-CZ3 4.48Å; I61-W544 HydrophobicContact CD1-CE3 4.11Å; I61-W544 HydrophobicContact CD1-CZ3 4.05Å; N535-W544 VanDerWaalsContact CA-O 3.26Å; N535-W544 WeakPolarHBondContact CA-O 3.41Å; N535-W544 VanDerWaalsContact CB-O 3.28Å; N535-W544 WeakPolarHBondContact CB-O 3.44Å; W538-W544 HydrophobicContact CE3-CB 3.98Å; W538-W544 HydrophobicContact CZ3-CB 4.15Å; W538-W544 HydrophobicContact CZ3-CD2 4.47Å; W538-W544 AromaticContact CZ3-CE3 3.98Å; W538-W544 HydrophobicContact CZ3-CE3 3.98Å; W544-L546 HydrophobicContact CH2-CB 3.95Å; W544-L546 HydrophobicContact CH2-CD1 3.78Å; W544-L546 HydrophobicContact CH2-CG 4.18Å; W544-L546 HydrophobicContact CZ2-CB 3.79Å; W544-L546 HydrophobicContact CZ2-CD1 4.47Å; W544-L546 HydrophobicContact CZ2-CG 4.5Å; W544-L546 HydrophobicContact CZ3-CB 4.5Å; W544-L546 HydrophobicContact CZ3-CD1 4.07Å; W544-L546 HydrophobicContact CZ3-CG 4.37Å; W544-G547 PolarHBondContact NE1-O 3.22Å; W544-F549 HydrophobicContact CH2-CE1 4.48Å; W544-F549 AromaticContact CZ2-CD1 3.88Å; W544-F549 HydrophobicContact CZ2-CD1 3.88Å; W544-F549 AromaticContact CZ2-CE1 3.67Å; W544-F549 HydrophobicContact CZ2-CE1 3.67Å
545N89.4Confident86.1Confident117 Ų11751.1 Ų51.163%0.62629%0.287SS*.  trans-120.7-6.5-17464.2-11.7000114.7G547N545-G547 PolarHBondContact O-N 3.46Å
546L88Confident85.7Confident87 Ų8753.5 Ų53.546%0.45530%0.3SS..SBendtrans-82.27.9-173.7-59.2-176.4000114.8I54 E57 W544I54-L546 HydrophobicContact CD1-CB 4.11Å; I54-L546 VanDerWaalsContact CD1-O 3.28Å; I54-L546 WeakPolarHBondContact CD1-O 3.28Å; I54-L546 HydrophobicContact CG1-CB 4.16Å; E57-L546 HydrophobicContact CB-CD1 4.06Å; E57-L546 HydrophobicContact CG-CD1 3.95Å; W544-L546 HydrophobicContact CH2-CB 3.95Å; W544-L546 HydrophobicContact CH2-CD1 3.78Å; W544-L546 HydrophobicContact CH2-CG 4.18Å; W544-L546 HydrophobicContact CZ2-CB 3.79Å; W544-L546 HydrophobicContact CZ2-CD1 4.47Å; W544-L546 HydrophobicContact CZ2-CG 4.5Å; W544-L546 HydrophobicContact CZ3-CB 4.5Å; W544-L546 HydrophobicContact CZ3-CD1 4.07Å; W544-L546 HydrophobicContact CZ3-CG 4.37Å
547G87.2Confident85.5Confident24 Ų2453.1 Ų53.125%0.24730%0.298CS..  trans90.4173.3179.600000113.8N535 W544 N545N535-G547 WeakPolarHBondContact OD1-CA 3.31Å; N535-G547 PolarHBondContact OD1-N 2.84Å; N535-G547 VanDerWaalsContact OD1-N 3.1Å; W544-G547 PolarHBondContact NE1-O 3.22Å; N545-G547 PolarHBondContact O-N 3.46Å
548S88.8Confident85.5Confident79 Ų7951.3 Ų51.355%0.55229%0.289SS*.  trans-80.4139.9-177.356.10000113.1H533H533-S548 CarbonylContact O-C 3.4Å; H533-S548 WeakPolarHBondContact O-CA 3.39Å; H533-S548 VanDerWaalsContact O-CB 3.27Å; H533-S548 WeakPolarHBondContact O-CB 3.27Å
549F90.2Very high85.5Confident17 Ų1752.4 Ų52.48%0.07530%0.297CS..EExtended strand (participates in β ladder)trans-140172.5175.173.4-88.1000112.2I54 H55 F58 V111 T532 H533 W544 A551I54-F549 HydrophobicContact CD1-CB 4.22Å; I54-F549 HydrophobicContact CD1-CD1 4.16Å; I54-F549 HydrophobicContact CG1-CD1 4.15Å; H55-F549 AromaticContact CD2-CD2 3.31Å; H55-F549 WeakPolarHBondContact CD2-CD2 3.25Å; H55-F549 AromaticContact CD2-CE2 3.71Å; H55-F549 AromaticContact CD2-CG 3.92Å; H55-F549 AromaticContact NE2-CD2 3.44Å; H55-F549 WeakPolarHBondContact NE2-CD2 3.36Å; F58-F549 HydrophobicContact CB-CE1 3.98Å; F58-F549 HydrophobicContact CB-CZ 3.86Å; F58-F549 HydrophobicContact CD1-CE1 4.38Å; F58-F549 AromaticContact CD1-CZ 3.64Å; F58-F549 HydrophobicContact CD1-CZ 3.64Å; F58-F549 AromaticContact CD2-CE1 3.63Å; F58-F549 HydrophobicContact CD2-CE1 3.63Å; F58-F549 AromaticContact CD2-CZ 3.7Å; F58-F549 HydrophobicContact CD2-CZ 3.7Å; F58-F549 HydrophobicContact CE1-CZ 4.01Å; F58-F549 HydrophobicContact CE2-CE1 4.17Å; F58-F549 HydrophobicContact CE2-CZ 4.1Å; F58-F549 AromaticContact CG-CE1 3.74Å; F58-F549 HydrophobicContact CG-CE1 3.74Å; F58-F549 AromaticContact CG-CZ 3.44Å; F58-F549 HydrophobicContact CG-CZ 3.44Å; F58-F549 VanDerWaalsContact CG-CZ 3.44Å; F58-F549 HydrophobicContact CZ-CZ 4.23Å; V111-F549 HydrophobicContact CG1-CE2 4.11Å; V111-F549 HydrophobicContact CG1-CZ 4.37Å; T532-F549 WeakPolarHBondContact CA-O 3.3Å; H533-F549 HydrophobicContact CB-CD1 4.01Å; H533-F549 HydrophobicContact CB-CE1 3.53Å; H533-F549 HydrophobicContact CB-CE2 4.33Å; H533-F549 HydrophobicContact CB-CZ 3.69Å; H533-F549 AromaticContact CD2-CE2 3.78Å; H533-F549 AromaticContact CD2-CZ 3.6Å; H533-F549 AromaticContact CG-CZ 3.8Å; H533-F549 PolarHBondContact N-O 2.98Å; H533-F549 PolarHBondContact O-N 3.27Å; W544-F549 HydrophobicContact CH2-CE1 4.48Å; W544-F549 AromaticContact CZ2-CD1 3.88Å; W544-F549 HydrophobicContact CZ2-CD1 3.88Å; W544-F549 AromaticContact CZ2-CE1 3.67Å; W544-F549 HydrophobicContact CZ2-CE1 3.67Å; F549-A551 HydrophobicContact CE2-CB 4.27Å
550C88.2Confident85.9Confident38 Ų3845 Ų4526%0.25726%0.262SS..EExtended strand (participates in β ladder)trans-117.6129.7-178.1-173.20000112.5C523C523-C550 WeakPolarHBondContact CA-SG 3.26Å; C523-C550 HydrophobicContact CB-CB 3.63Å; C523-C550 WeakPolarHBondContact CB-SG 3.27Å; C523-C550 VanDerWaalsContact SG-CA 3.56Å; C523-C550 WeakPolarHBondContact SG-CB 3.33Å; C523-C550 CovalentContact SG-SG 2.04Å; C523-C550 PolarHBondContact SG-SG 3.02Å
551A87Confident86.4Confident3 Ų344.7 Ų44.73%0.02526%0.257CS..EExtended strand (participates in β ladder)trans-116.2119.4174.300000111.1V111 C530 F531 F549 T553V111-A551 HydrophobicContact CB-CB 3.98Å; V111-A551 HydrophobicContact CG1-CB 4.5Å; V111-A551 HydrophobicContact CG2-CB 4.03Å; C530-A551 CarbonylContact C-O 3.59Å; C530-A551 VanDerWaalsContact CA-O 3.27Å; C530-A551 WeakPolarHBondContact CA-O 3.47Å; F531-A551 PolarHBondContact N-O 2.04Å; F531-A551 PolarHBondContact O-N 3.46Å; F549-A551 HydrophobicContact CE2-CB 4.27Å; A551-T553 HydrophobicContact CB-CG2 4.45Å
552C87Confident87.2Confident20 Ų2042.4 Ų42.414%0.13524%0.237CC..EExtended strand (participates in β ladder)trans-113.876.8-179.5-62.20000111.3L525 L528 C530L525-C552 HydrophobicContact CD1-CB 4.01Å; L528-C552 HydrophobicContact CB-CB 4.24Å; L528-C552 HydrophobicContact CD1-CB 4.06Å; C530-C552 HydrophobicContact CB-CB 4.05Å; C530-C552 WeakPolarHBondContact CB-SG 3.47Å; C530-C552 WeakPolarHBondContact SG-CB 3.44Å; C530-C552 CovalentContact SG-SG 2.04Å; C530-C552 PolarHBondContact SG-SG 3.44Å
553T83.4Confident87.8Confident7 Ų740.6 Ų40.64%0.04323%0.226CC..EExtended strand (participates in β ladder)trans-102.98-165.556.80000115.7L110 V111 K112 M116 A551L110-T553 HydrophobicContact CB-CG2 4.19Å; L110-T553 HydrophobicContact CD2-CG2 4.36Å; V111-T553 HydrophobicContact CB-CG2 4.45Å; K112-T553 WeakPolarHBondContact O-CB 3.17Å; K112-T553 WeakPolarHBondContact O-CG2 3.39Å; K112-T553 PolarHBondContact O-OG1 3.48Å; M116-T553 WeakPolarHBondContact CE-O 3.34Å; A551-T553 HydrophobicContact CB-CG2 4.45Å
554S83.7Confident88.2Confident12 Ų1235.2 Ų35.28%0.08420%0.202CC..EExtended strand (participates in β ladder)trans-161.1174.4-177.751.20000113.4L528 T529L528-S554 WeakPolarHBondContact CA-O 3.46Å; L528-S554 WeakPolarHBondContact CD2-O 3.1Å; T529-S554 PolarHBondContact N-O 3.37Å; T529-S554 PolarHBondContact OG1-O 2.94Å; T529-S554 PolarHBondContact OG1-OG 3Å
555S84.1Confident88.4Confident2 Ų235.3 Ų35.31%0.01420%0.203CC..  trans-145.3154.8169.1-178.10000112R199 G527 N557R199-S555 PolarHBondContact NH2-O 3.39Å; G527-S555 WeakPolarHBondContact O-CB 3.43Å; G527-S555 PolarHBondContact O-OG 2.79Å; S555-N557 VanDerWaalsContact C-N 3.31Å; S555-N557 PolarHBondContact OG-N 2.74Å
556N77.5Confident88.6Confident122 Ų12232.2 Ų32.265%0.65219%0.188SC*.SBendtrans-77-16167.3-68-54.2000113.2
557N78Confident88.5Confident128 Ų12830.7 Ų30.768%0.68418%0.18SC*.SBendtrans-98.6-6179.1-692.7000112.3S555 T559S555-N557 VanDerWaalsContact C-N 3.31Å; S555-N557 PolarHBondContact OG-N 2.74Å; N557-T559 PolarHBondContact O-N 3.32Å
558N84.8Confident88.4Confident3 Ų338.6 Ų38.62%0.01621%0.211CC..  trans-70.3101172.5-150.729.3000108.7H42 W43 I44 R199H42-N558 PolarHBondContact NE2-ND2 2.68Å; W43-N558 PolarHBondContact NE1-OD1 3.32Å; W43-N558 VanDerWaalsContact NE1-OD1 3.16Å; I44-N558 HydrophobicContact CD1-CB 3.95Å; R199-N558 WeakPolarHBondContact CD-O 3.08Å; R199-N558 PolarHBondContact NE-O 2.84Å
559T90.1Very high88.3Confident27 Ų2739.3 Ų39.317%0.16621%0.212CC..  trans-117.4123.6177.6-61.80000108.2R199 N557 W561 A578R199-T559 CarbonylContact O-C 3.53Å; R199-T559 WeakPolarHBondContact O-CA 3.04Å; R199-T559 WeakPolarHBondContact O-CG2 3.1Å; N557-T559 PolarHBondContact O-N 3.32Å; T559-W561 HydrophobicContact CG2-CH2 3.68Å; T559-W561 HydrophobicContact CG2-CZ2 3.48Å; T559-W561 VanDerWaalsContact CG2-CZ2 3.48Å; T559-W561 HydrophobicContact CG2-CZ3 4.47Å; T559-A578 HydrophobicContact CG2-CB 3.92Å; T559-A578 PolarHBondContact O-N 3.26Å
560Y93.3Very high88.4Confident10 Ų1043.1 Ų43.14%0.03923%0.229CC..EExtended strand (participates in β ladder)trans-147.7157.9-178.559-108.8000111.3M116 P117 V197 E198 R199 E576 F577M116-Y560 PolarHBondContact O-OH 3.45Å; P117-Y560 HydrophobicContact CB-CD2 4.08Å; P117-Y560 HydrophobicContact CB-CE2 3.72Å; V197-Y560 HydrophobicContact CG1-CE2 4.29Å; E198-Y560 WeakPolarHBondContact CA-O 3.35Å; R199-Y560 HydrophobicContact CB-CD1 4.05Å; R199-Y560 HydrophobicContact CB-CD2 4.02Å; R199-Y560 HydrophobicContact CB-CE1 3.64Å; R199-Y560 HydrophobicContact CB-CE2 3.58Å; R199-Y560 HydrophobicContact CB-CG 4.22Å; R199-Y560 HydrophobicContact CG-CE1 4.1Å; R199-Y560 PolarHBondContact N-O 3.28Å; R199-Y560 PolarHBondContact O-N 3.09Å; Y560-E576 CarbonylContact C-O 3.57Å; Y560-E576 VanDerWaalsContact CA-O 3.29Å; Y560-E576 WeakPolarHBondContact CA-O 3.5Å; Y560-F577 HydrophobicContact CD1-CD1 4.28Å; Y560-F577 AromaticContact CD1-CE1 3.71Å; Y560-F577 HydrophobicContact CD1-CE1 3.71Å; Y560-F577 HydrophobicContact CD1-CZ 4.37Å; Y560-F577 HydrophobicContact CG-CD1 4.46Å; Y560-F577 HydrophobicContact CG-CE1 4.07Å; Y560-F577 HydrophobicContact CG-CZ 4.48Å
561W94.8Very high88.7Confident28 Ų2842.8 Ų42.811%0.10623%0.225CC..EExtended strand (participates in β ladder)trans-134.2130.3172-52.6-82.5000108L196 V197 E198 T559 E576 A578 L613 R617L196-W561 HydrophobicContact CD1-CB 4.23Å; V197-W561 CarbonylContact O-C 3.35Å; E198-W561 VanDerWaalsContact CB-CD1 3.46Å; E198-W561 HydrophobicContact CB-CG 4.37Å; E198-W561 PolarHBondContact OE2-NE1 3.02Å; T559-W561 HydrophobicContact CG2-CH2 3.68Å; T559-W561 HydrophobicContact CG2-CZ2 3.48Å; T559-W561 VanDerWaalsContact CG2-CZ2 3.48Å; T559-W561 HydrophobicContact CG2-CZ3 4.47Å; W561-E576 PolarHBondContact N-O 3.18Å; W561-E576 PolarHBondContact O-N 3.18Å; W561-A578 HydrophobicContact CH2-CB 4.03Å; W561-A578 HydrophobicContact CZ3-CB 4.11Å; W561-L613 HydrophobicContact CB-CD1 4.09Å; W561-L613 HydrophobicContact CB-CD2 4.08Å; W561-L613 HydrophobicContact CB-CG 4.29Å; W561-R617 HydrophobicContact CG-CG 4.45Å
562C96.7Very high89.1Confident0 Ų043.4 Ų43.40%023%0.227CC..EExtended strand (participates in β ladder)trans-131.7143.2-175.7-52.60000112P117 L196 V197 L573 F574 C575P117-C562 WeakPolarHBondContact CB-SG 3.43Å; L196-C562 WeakPolarHBondContact CA-O 3.2Å; V197-C562 HydrophobicContact CB-CB 4.26Å; V197-C562 PolarHBondContact N-O 3.23Å; V197-C562 PolarHBondContact O-N 3.44Å; C562-L573 HydrophobicContact CB-CD1 3.74Å; C562-F574 CarbonylContact C-O 3.45Å; C562-F574 WeakPolarHBondContact CA-O 3.41Å; C562-F574 VanDerWaalsContact CB-O 3.23Å; C562-F574 WeakPolarHBondContact CB-O 3.29Å; C562-C575 HydrophobicContact CB-CB 4.01Å; C562-C575 WeakPolarHBondContact CB-SG 3.34Å; C562-C575 VanDerWaalsContact SG-CA 3.57Å; C562-C575 WeakPolarHBondContact SG-CB 3.25Å; C562-C575 CovalentContact SG-SG 2.03Å; C562-C575 PolarHBondContact SG-SG 3.09Å
563L95.7Very high89.6Confident0 Ų042.4 Ų42.40%022%0.221CC..EExtended strand (participates in β ladder)trans-98.8112.1172.5-162.572.4000107.6T194 F572 F574 L609 Q612 L613 L616T194-L563 HydrophobicContact CG2-CD1 3.39Å; T194-L563 HydrophobicContact CG2-CD2 4.2Å; T194-L563 HydrophobicContact CG2-CG 3.55Å; L563-F572 HydrophobicContact CD2-CE2 4.34Å; L563-F574 HydrophobicContact CB-CB 4.38Å; L563-F574 HydrophobicContact CB-CD1 4.34Å; L563-F574 PolarHBondContact N-O 2.91Å; L563-F574 PolarHBondContact O-N 2.57Å; L563-L609 HydrophobicContact CD2-CD2 3.83Å; L563-Q612 HydrophobicContact CD1-CG 4.15Å; L563-Q612 HydrophobicContact CD2-CB 4.24Å; L563-Q612 HydrophobicContact CD2-CG 4.13Å; L563-L613 HydrophobicContact CB-CD1 4.2Å; L563-L616 HydrophobicContact CD1-CD1 3.56Å
564R95.4Very high90.3Very high12 Ų1242.1 Ų42.15%0.04522%0.219CC..EExtended strand (participates in β ladder)trans-104.4121.3172.7-175.374.3178.291.53.8108.3D119 I122 T194 F195 N571 F572 L573D119-R564 IonicContact OD1-CZ 2.73Å; D119-R564 IonicContact OD1-NE 3.42Å; D119-R564 PolarHBondContact OD1-NE 3.26Å; D119-R564 IonicContact OD1-NH2 2.96Å; D119-R564 PolarHBondContact OD1-NH2 2.92Å; I122-R564 HydrophobicContact CD1-CG 4.47Å; T194-R564 WeakPolarHBondContact CA-O 3.47Å; F195-R564 HydrophobicContact CD1-CB 4Å; F195-R564 HydrophobicContact CD1-CG 4.31Å; F195-R564 WeakPolarHBondContact CD1-O 3.33Å; F195-R564 HydrophobicContact CE1-CB 3.58Å; F195-R564 HydrophobicContact CE1-CG 3.46Å; F195-R564 VanDerWaalsContact CE1-CG 3.46Å; F195-R564 HydrophobicContact CE2-CB 4.15Å; F195-R564 HydrophobicContact CE2-CG 4.5Å; F195-R564 HydrophobicContact CG-CB 4.48Å; F195-R564 HydrophobicContact CZ-CB 3.68Å; F195-R564 HydrophobicContact CZ-CG 3.59Å; F195-R564 PolarHBondContact N-O 2.87Å; F195-R564 PolarHBondContact O-N 2.81Å; R564-N571 PolarHBondContact NH1-OD1 3Å; R564-N571 PolarHBondContact NH2-OD1 2.99Å; R564-N571 VanDerWaalsContact NH2-OD1 3.11Å; R564-F572 WeakPolarHBondContact CD-O 3.38Å; R564-F572 PolarHBondContact NH1-O 3.29Å; R564-L573 HydrophobicContact CB-CD1 4.18Å
565T93.9Very high90.9Very high5 Ų541.6 Ų41.63%0.03122%0.215CC..EExtended strand (participates in β ladder)trans-120.2131-176.5-51.40000109.6D193 T194 H570 N571 F572D193-T565 CarbonylContact O-C 3.54Å; D193-T565 WeakPolarHBondContact O-CA 3.28Å; T194-T565 WeakPolarHBondContact CG2-OG1 3.42Å; T565-H570 HydrophobicContact CG2-CB 4.43Å; T565-N571 CarbonylContact O-C 3.54Å; T565-N571 VanDerWaalsContact O-CA 3.27Å; T565-N571 WeakPolarHBondContact O-CA 3.32Å; T565-F572 HydrophobicContact CG2-CE1 3.92Å; T565-F572 HydrophobicContact CG2-CZ 4.06Å; T565-F572 PolarHBondContact N-O 3.19Å; T565-F572 PolarHBondContact O-N 3.11Å; T565-F572 WeakPolarHBondContact OG1-CE2 3.44Å; T565-F572 WeakPolarHBondContact OG1-CZ 3.31Å
566V92Very high91.4Very high52 Ų5242.7 Ų42.732%0.31522%0.22SC..EExtended strand (participates in β ladder)trans-139.8111.2171.5-167.90000109.1I142 D193 H570I142-V566 HydrophobicContact CD1-CB 3.86Å; I142-V566 HydrophobicContact CD1-CG2 4.12Å; I142-V566 HydrophobicContact CG1-CB 4.13Å; I142-V566 HydrophobicContact CG1-CG2 4.5Å; D193-V566 PolarHBondContact O-N 3.41Å; V566-H570 CarbonylContact C-O 3.53Å; V566-H570 WeakPolarHBondContact CA-O 3.03Å
567N87.3Confident92.2Very high55 Ų5537.2 Ų37.229%0.29419%0.191SC..SBendtrans-141.8-175.5168.165.948.8000110.4D193 T569 H570D193-N567 HydrophobicContact CB-CB 3.92Å; N567-T569 PolarHBondContact O-N 2.7Å; N567-T569 PolarHBondContact OD1-N 3.03Å; N567-T569 PolarHBondContact OD1-OG1 3.41Å; N567-H570 PolarHBondContact N-O 2.87Å; N567-H570 PolarHBondContact OD1-N 2.7Å
568E84.8Confident92.7Very high191 Ų19134.3 Ų34.389%0.89318%0.184SC*.SBendtrans-58.6-15.2-177.3-60.4175.5176.300114.9
569T86.9Confident92.7Very high93 Ų9338.9 Ų38.957%0.57121%0.212SC*.SBendtrans-127.9-24.2-173.657.70000114.3N567N567-T569 PolarHBondContact O-N 2.7Å; N567-T569 PolarHBondContact OD1-N 3.03Å; N567-T569 PolarHBondContact OD1-OG1 3.41Å
570H91.1Very high92.6Very high97 Ų9739.8 Ų39.845%0.44923%0.227SC..  trans-133.1130.6-173.5-68.578000110.5T565 V566 N567 F572T565-H570 HydrophobicContact CG2-CB 4.43Å; V566-H570 CarbonylContact C-O 3.53Å; V566-H570 WeakPolarHBondContact CA-O 3.03Å; N567-H570 PolarHBondContact N-O 2.87Å; N567-H570 PolarHBondContact OD1-N 2.7Å; H570-F572 HydrophobicContact CB-CD1 4.01Å; H570-F572 HydrophobicContact CB-CE1 4.03Å
571N95.1Very high92.5Very high32 Ų3242.2 Ų42.217%0.17124%0.238CC..EExtended strand (participates in β ladder)trans-140.871.7-179.6-179.413.6000109.7R564 T565 M587 N588R564-N571 PolarHBondContact NH1-OD1 3Å; R564-N571 PolarHBondContact NH2-OD1 2.99Å; R564-N571 VanDerWaalsContact NH2-OD1 3.11Å; T565-N571 CarbonylContact O-C 3.54Å; T565-N571 VanDerWaalsContact O-CA 3.27Å; T565-N571 WeakPolarHBondContact O-CA 3.32Å; N571-M587 WeakPolarHBondContact O-CA 3.02Å; N571-M587 WeakPolarHBondContact O-CB 3.44Å; N571-M587 WeakPolarHBondContact O-CG 3.26Å; N571-M587 PolarHBondContact O-N 2.8Å; N571-N588 VanDerWaalsContact CB-OD1 3.22Å; N571-N588 WeakPolarHBondContact CB-OD1 3.35Å; N571-N588 PolarHBondContact ND2-OD1 2.81Å
572F96.2Very high92.5Very high15 Ų1543.1 Ų43.17%0.06625%0.245CC..EExtended strand (participates in β ladder)trans-121.3163.8-172.165.2-102.3000113.4L563 R564 T565 H570 F574 Y584 F585 L609L563-F572 HydrophobicContact CD2-CE2 4.34Å; R564-F572 WeakPolarHBondContact CD-O 3.38Å; R564-F572 PolarHBondContact NH1-O 3.29Å; T565-F572 HydrophobicContact CG2-CE1 3.92Å; T565-F572 HydrophobicContact CG2-CZ 4.06Å; T565-F572 PolarHBondContact N-O 3.19Å; T565-F572 PolarHBondContact O-N 3.11Å; T565-F572 WeakPolarHBondContact OG1-CE2 3.44Å; T565-F572 WeakPolarHBondContact OG1-CZ 3.31Å; H570-F572 HydrophobicContact CB-CD1 4.01Å; H570-F572 HydrophobicContact CB-CE1 4.03Å; F572-F574 HydrophobicContact CD2-CB 4.35Å; F572-F574 HydrophobicContact CE2-CB 4.39Å; F572-Y584 HydrophobicContact CB-CE1 4.43Å; F572-Y584 HydrophobicContact CB-CE2 4.02Å; F572-Y584 WeakPolarHBondContact CB-OH 3.26Å; F572-Y584 HydrophobicContact CD1-CE2 4.49Å; F572-Y584 AromaticContact CD2-CE2 3.78Å; F572-Y584 HydrophobicContact CD2-CE2 3.78Å; F572-Y584 HydrophobicContact CE2-CE2 4.36Å; F572-Y584 AromaticContact CG-CE2 3.86Å; F572-Y584 HydrophobicContact CG-CE2 3.86Å; F572-Y584 AromaticContact CG-CZ 3.94Å; F572-F585 CarbonylContact C-O 3.59Å; F572-F585 WeakPolarHBondContact CA-O 3.22Å; F572-F585 WeakPolarHBondContact CB-O 3.43Å; F572-L609 HydrophobicContact CE2-CD2 3.72Å; F572-L609 HydrophobicContact CZ-CD2 3.56Å
573L97.1Very high92.5Very high0 Ų043.1 Ų43.10%025%0.245CC..EExtended strand (participates in β ladder)trans-123.6119.8165.6175.465.8000108.2P117 C562 R564 Y584 F585 Q593P117-L573 WeakPolarHBondContact O-CD2 3.43Å; C562-L573 HydrophobicContact CB-CD1 3.74Å; R564-L573 HydrophobicContact CB-CD1 4.18Å; L573-Y584 WeakPolarHBondContact O-CA 3.37Å; L573-F585 HydrophobicContact CD2-CD2 4.28Å; L573-F585 PolarHBondContact N-O 2.86Å; L573-F585 PolarHBondContact O-N 3.41Å; L573-Q593 VanDerWaalsContact CD2-NE2 3.29Å
574F97.4Very high92.6Very high1 Ų144.4 Ų44.40%0.00425%0.249CC..EExtended strand (participates in β ladder)trans-112.5134170.9170.7-112.8000109.1C562 L563 F572 E576 L582 E583 Y584 L606 L609 L613C562-F574 CarbonylContact C-O 3.45Å; C562-F574 WeakPolarHBondContact CA-O 3.41Å; C562-F574 VanDerWaalsContact CB-O 3.23Å; C562-F574 WeakPolarHBondContact CB-O 3.29Å; L563-F574 HydrophobicContact CB-CB 4.38Å; L563-F574 HydrophobicContact CB-CD1 4.34Å; L563-F574 PolarHBondContact N-O 2.91Å; L563-F574 PolarHBondContact O-N 2.57Å; F572-F574 HydrophobicContact CD2-CB 4.35Å; F572-F574 HydrophobicContact CE2-CB 4.39Å; F574-E576 HydrophobicContact CE1-CG 3.75Å; F574-E576 HydrophobicContact CZ-CG 3.72Å; F574-E576 WeakPolarHBondContact CZ-OE1 3.39Å; F574-L582 HydrophobicContact CZ-CD2 4.37Å; F574-E583 CarbonylContact C-O 3.55Å; F574-E583 WeakPolarHBondContact CA-O 3.49Å; F574-E583 WeakPolarHBondContact CD2-O 3.41Å; F574-Y584 HydrophobicContact CB-CD2 3.99Å; F574-Y584 HydrophobicContact CD2-CD2 4.15Å; F574-Y584 HydrophobicContact CG-CD2 4.49Å; F574-L606 HydrophobicContact CD2-CD2 4.46Å; F574-L606 HydrophobicContact CE2-CD2 4.02Å; F574-L609 HydrophobicContact CB-CD1 4.28Å; F574-L609 HydrophobicContact CD1-CB 3.67Å; F574-L609 HydrophobicContact CD1-CD1 4.43Å; F574-L609 HydrophobicContact CD2-CD1 4.29Å; F574-L609 HydrophobicContact CE1-CB 3.76Å; F574-L609 HydrophobicContact CG-CB 4.17Å; F574-L609 HydrophobicContact CG-CD1 4.08Å; F574-L609 HydrophobicContact CZ-CB 4.35Å; F574-L613 HydrophobicContact CE1-CD2 4.37Å
575C96.8Very high92.7Very high0 Ų043.9 Ų43.90%025%0.248CC..EExtended strand (participates in β ladder)trans-132.9135.7-177.6-73.70000112.9P117 C562 F577 L582 E583P117-C575 VanDerWaalsContact CB-SG 3.51Å; C562-C575 HydrophobicContact CB-CB 4.01Å; C562-C575 WeakPolarHBondContact CB-SG 3.34Å; C562-C575 VanDerWaalsContact SG-CA 3.57Å; C562-C575 WeakPolarHBondContact SG-CB 3.25Å; C562-C575 CovalentContact SG-SG 2.03Å; C562-C575 PolarHBondContact SG-SG 3.09Å; C575-F577 HydrophobicContact CB-CD2 4.49Å; C575-F577 HydrophobicContact CB-CE2 3.85Å; C575-L582 WeakPolarHBondContact O-CA 3.4Å; C575-E583 HydrophobicContact CB-CB 4.19Å; C575-E583 PolarHBondContact N-O 2.92Å; C575-E583 PolarHBondContact O-N 2.85Å
576E95.4Very high92.8Very high25 Ų2545.6 Ų45.612%0.11726%0.257CS..EExtended strand (participates in β ladder)trans-112.7121.3169.4-57.1-165167.700110.5Y560 W561 F574 L582 H610 L613Y560-E576 CarbonylContact C-O 3.57Å; Y560-E576 VanDerWaalsContact CA-O 3.29Å; Y560-E576 WeakPolarHBondContact CA-O 3.5Å; W561-E576 PolarHBondContact N-O 3.18Å; W561-E576 PolarHBondContact O-N 3.18Å; F574-E576 HydrophobicContact CE1-CG 3.75Å; F574-E576 HydrophobicContact CZ-CG 3.72Å; F574-E576 WeakPolarHBondContact CZ-OE1 3.39Å; E576-L582 HydrophobicContact CB-CD2 4.25Å; E576-L582 HydrophobicContact CG-CD2 3.73Å; E576-H610 WeakPolarHBondContact OE1-CB 3.15Å; E576-H610 IonicContact OE1-CE1 2.77Å; E576-H610 IonicContact OE1-CG 2.63Å; E576-H610 IonicContact OE1-ND1 2.63Å; E576-H610 PolarHBondContact OE1-ND1 3.1Å; E576-H610 IonicContact OE2-CE1 3.61Å; E576-H610 PolarHBondContact OE2-CE1 2.99Å; E576-H610 IonicContact OE2-ND1 3.89Å; E576-H610 PolarHBondContact OE2-ND1 2.8Å; E576-L613 HydrophobicContact CB-CD2 3.95Å; E576-L613 HydrophobicContact CG-CD2 3.55Å
577F92.9Very high92.9Very high8 Ų843.8 Ų43.84%0.03525%0.245CC..EExtended strand (participates in β ladder)trans-92.1148.5174.9-68.9-100.2000110.2H42 P117 Y560 C575 T579 G580 F581 E583H42-F577 HydrophobicContact CB-CD1 3.69Å; H42-F577 HydrophobicContact CB-CD2 4.01Å; H42-F577 HydrophobicContact CB-CE1 3.39Å; H42-F577 HydrophobicContact CB-CE2 3.75Å; H42-F577 HydrophobicContact CB-CG 4Å; H42-F577 HydrophobicContact CB-CZ 3.43Å; H42-F577 VanDerWaalsContact CB-CZ 3.43Å; H42-F577 AromaticContact CD2-CE1 3.48Å; H42-F577 VanDerWaalsContact CD2-CE1 3.48Å; H42-F577 WeakPolarHBondContact CD2-CE1 3.18Å; H42-F577 AromaticContact CD2-CZ 4Å; H42-F577 AromaticContact CG-CE1 3.25Å; H42-F577 AromaticContact CG-CZ 3.34Å; H42-F577 AromaticContact ND1-CE1 3.69Å; H42-F577 AromaticContact ND1-CZ 3.37Å; H42-F577 WeakPolarHBondContact ND1-CZ 3.36Å; P117-F577 HydrophobicContact CG-CZ 4.13Å; Y560-F577 HydrophobicContact CD1-CD1 4.28Å; Y560-F577 AromaticContact CD1-CE1 3.71Å; Y560-F577 HydrophobicContact CD1-CE1 3.71Å; Y560-F577 HydrophobicContact CD1-CZ 4.37Å; Y560-F577 HydrophobicContact CG-CD1 4.46Å; Y560-F577 HydrophobicContact CG-CE1 4.07Å; Y560-F577 HydrophobicContact CG-CZ 4.48Å; C575-F577 HydrophobicContact CB-CD2 4.49Å; C575-F577 HydrophobicContact CB-CE2 3.85Å; F577-T579 WeakPolarHBondContact CB-OG1 3.34Å; F577-T579 PolarHBondContact O-N 3.17Å; F577-G580 PolarHBondContact O-N 2.87Å; F577-F581 HydrophobicContact CB-CB 4.19Å; F577-F581 HydrophobicContact CD2-CD1 4.41Å; F577-F581 PolarHBondContact N-O 3.36Å; F577-E583 HydrophobicContact CE2-CG 3.85Å
578A88.3Confident93.3Very high66 Ų6645.9 Ų45.955%0.54526%0.256SS..THydrogen-bonded Turntrans-63-3.9177.300000114.6T559 W561T559-A578 HydrophobicContact CG2-CB 3.92Å; T559-A578 PolarHBondContact O-N 3.26Å; W561-A578 HydrophobicContact CH2-CB 4.03Å; W561-A578 HydrophobicContact CZ3-CB 4.11Å
579T85.6Confident93.8Very high99 Ų9942.2 Ų42.261%0.60725%0.247SC*.THydrogen-bonded Turntrans-85.5-6.1169.551.40000113.9F577 F581F577-T579 WeakPolarHBondContact CB-OG1 3.34Å; F577-T579 PolarHBondContact O-N 3.17Å; T579-F581 VanDerWaalsContact C-N 3.31Å; T579-F581 PolarHBondContact OG1-N 2.92Å
580G87Confident94.2Very high46 Ų4638.8 Ų38.847%0.47423%0.225SC..SBendtrans81.25.8-168.900000114.2F577F577-G580 PolarHBondContact O-N 2.87Å
581F92Very high94.4Very high61 Ų6137.5 Ų37.527%0.26823%0.225SC..  trans-76.4142.4173.9-162.1-91.5000110.7D40 K41 H42 F577 T579 E583D40-F581 WeakPolarHBondContact O-CE1 3.48Å; D40-F581 VanDerWaalsContact O-CZ 3.29Å; D40-F581 WeakPolarHBondContact O-CZ 3.39Å; K41-F581 WeakPolarHBondContact O-CZ 3.12Å; H42-F581 HydrophobicContact CB-CD1 4.26Å; F577-F581 HydrophobicContact CB-CB 4.19Å; F577-F581 HydrophobicContact CD2-CD1 4.41Å; F577-F581 PolarHBondContact N-O 3.36Å; T579-F581 VanDerWaalsContact C-N 3.31Å; T579-F581 PolarHBondContact OG1-N 2.92Å; F581-E583 HydrophobicContact CD1-CG 4.11Å; F581-E583 HydrophobicContact CE1-CG 3.88Å
582L95.3Very high94.4Very high48 Ų4840.8 Ų40.825%0.25124%0.236SC..EExtended strand (participates in β ladder)trans-121.8135-177.3-55177.6000110.2F574 C575 E576 N596 V598F574-L582 HydrophobicContact CZ-CD2 4.37Å; C575-L582 WeakPolarHBondContact O-CA 3.4Å; E576-L582 HydrophobicContact CB-CD2 4.25Å; E576-L582 HydrophobicContact CG-CD2 3.73Å; L582-N596 PolarHBondContact O-ND2 2.89Å; L582-V598 HydrophobicContact CB-CG2 3.88Å; L582-V598 HydrophobicContact CD1-CG2 4.49Å
583E96.6Very high94.4Very high0 Ų040.1 Ų40.10%023%0.233CC..EExtended strand (participates in β ladder)trans-120.8141.6169.1-59.8175.7164.700110K41 H42 Y118 F574 C575 F577 F581 F585 N596K41-E583 WeakPolarHBondContact CA-OE1 3.45Å; K41-E583 WeakPolarHBondContact CB-OE1 3.37Å; H42-E583 IonicContact CG-OE1 2.91Å; H42-E583 PolarHBondContact N-OE1 3.16Å; H42-E583 IonicContact ND1-OE1 3.3Å; H42-E583 PolarHBondContact ND1-OE1 2.91Å; H42-E583 IonicContact ND1-OE2 3.04Å; Y118-E583 PolarHBondContact OH-OE1 3.17Å; Y118-E583 VanDerWaalsContact OH-OE1 3.12Å; Y118-E583 PolarHBondContact OH-OE2 2.97Å; F574-E583 CarbonylContact C-O 3.55Å; F574-E583 WeakPolarHBondContact CA-O 3.49Å; F574-E583 WeakPolarHBondContact CD2-O 3.41Å; C575-E583 HydrophobicContact CB-CB 4.19Å; C575-E583 PolarHBondContact N-O 2.92Å; C575-E583 PolarHBondContact O-N 2.85Å; F577-E583 HydrophobicContact CE2-CG 3.85Å; F581-E583 HydrophobicContact CD1-CG 4.11Å; F581-E583 HydrophobicContact CE1-CG 3.88Å; E583-F585 HydrophobicContact CB-CD2 4.48Å; E583-F585 HydrophobicContact CB-CE2 3.64Å; E583-F585 HydrophobicContact CB-CZ 3.99Å; E583-F585 HydrophobicContact CG-CE2 4.32Å; E583-F585 HydrophobicContact CG-CZ 4.33Å; E583-N596 WeakPolarHBondContact CA-OD1 3.27Å
584Y97.3Very high94.4Very high26 Ų2642 Ų4210%0.10224%0.243CC..EExtended strand (participates in β ladder)trans-138.2132.5169-176.6-83.8000109.3F572 L573 F574 D586 N596 T597 V601 L609F572-Y584 HydrophobicContact CB-CE1 4.43Å; F572-Y584 HydrophobicContact CB-CE2 4.02Å; F572-Y584 WeakPolarHBondContact CB-OH 3.26Å; F572-Y584 HydrophobicContact CD1-CE2 4.49Å; F572-Y584 AromaticContact CD2-CE2 3.78Å; F572-Y584 HydrophobicContact CD2-CE2 3.78Å; F572-Y584 HydrophobicContact CE2-CE2 4.36Å; F572-Y584 AromaticContact CG-CE2 3.86Å; F572-Y584 HydrophobicContact CG-CE2 3.86Å; F572-Y584 AromaticContact CG-CZ 3.94Å; L573-Y584 WeakPolarHBondContact O-CA 3.37Å; F574-Y584 HydrophobicContact CB-CD2 3.99Å; F574-Y584 HydrophobicContact CD2-CD2 4.15Å; F574-Y584 HydrophobicContact CG-CD2 4.49Å; Y584-D586 HydrophobicContact CE1-CB 4.35Å; Y584-N596 PolarHBondContact N-OD1 2.64Å; Y584-N596 PolarHBondContact O-OD1 2.75Å; Y584-T597 PolarHBondContact O-N 3.17Å; Y584-T597 PolarHBondContact O-OG1 2.83Å; Y584-V601 HydrophobicContact CD1-CG2 3.62Å; Y584-V601 HydrophobicContact CD2-CG2 4.23Å; Y584-V601 HydrophobicContact CE1-CG2 3.82Å; Y584-V601 HydrophobicContact CE2-CG2 4.4Å; Y584-V601 HydrophobicContact CG-CG2 3.86Å; Y584-L609 HydrophobicContact CD2-CD1 4.09Å; Y584-L609 HydrophobicContact CE2-CD1 3.9Å
585F97.1Very high94.2Very high1 Ų145.2 Ų45.20%0.00426%0.263CS..EExtended strand (participates in β ladder)trans-135.4127177.1-51.8-77.9000109.4K41 Y118 F572 L573 E583 M587 Q593 T595 N596K41-F585 HydrophobicContact CD-CZ 4.38Å; K41-F585 HydrophobicContact CG-CZ 4.39Å; Y118-F585 HydrophobicContact CD1-CE2 4.32Å; Y118-F585 AromaticContact CE1-CE2 3.81Å; Y118-F585 HydrophobicContact CE1-CE2 3.81Å; Y118-F585 HydrophobicContact CE1-CZ 4.01Å; F572-F585 CarbonylContact C-O 3.59Å; F572-F585 WeakPolarHBondContact CA-O 3.22Å; F572-F585 WeakPolarHBondContact CB-O 3.43Å; L573-F585 HydrophobicContact CD2-CD2 4.28Å; L573-F585 PolarHBondContact N-O 2.86Å; L573-F585 PolarHBondContact O-N 3.41Å; E583-F585 HydrophobicContact CB-CD2 4.48Å; E583-F585 HydrophobicContact CB-CE2 3.64Å; E583-F585 HydrophobicContact CB-CZ 3.99Å; E583-F585 HydrophobicContact CG-CE2 4.32Å; E583-F585 HydrophobicContact CG-CZ 4.33Å; F585-M587 HydrophobicContact CB-SD 4.43Å; F585-Q593 HydrophobicContact CB-CG 4.12Å; F585-Q593 HydrophobicContact CD1-CB 3.98Å; F585-Q593 HydrophobicContact CD1-CG 4.48Å; F585-Q593 HydrophobicContact CD2-CB 4.39Å; F585-Q593 HydrophobicContact CD2-CG 4.41Å; F585-Q593 HydrophobicContact CE1-CB 4.27Å; F585-Q593 VanDerWaalsContact CE1-O 3.3Å; F585-Q593 WeakPolarHBondContact CE1-O 3.36Å; F585-Q593 HydrophobicContact CG-CB 4.04Å; F585-Q593 HydrophobicContact CG-CG 4.09Å; F585-T595 WeakPolarHBondContact CD1-O 3.39Å; F585-N596 HydrophobicContact CE1-CB 4.11Å; F585-N596 HydrophobicContact CZ-CB 4.39Å
586D96.1Very high94.2Very high42 Ų4245.7 Ų45.723%0.22527%0.265CS..EExtended strand (participates in β ladder)trans-93113.8165.7-173.6-22.2000108.9Y584 N588 T589 D590Y584-D586 HydrophobicContact CE1-CB 4.35Å; D586-N588 PolarHBondContact O-N 2.93Å; D586-N588 VanDerWaalsContact OD1-CB 3.3Å; D586-N588 WeakPolarHBondContact OD1-CB 3.47Å; D586-N588 PolarHBondContact OD1-N 3.05Å; D586-T589 PolarHBondContact O-N 2.91Å; D586-T589 PolarHBondContact O-OG1 3.35Å; D586-T589 VanDerWaalsContact O-OG1 3.12Å; D586-D590 WeakPolarHBondContact O-CA 3.3Å; D586-D590 PolarHBondContact O-N 2.64Å
587M95.1Very high94.1Very high13 Ų1346.3 Ų46.36%0.06427%0.271CS..THydrogen-bonded Turntrans-76-11.1-174.9-51.2-66.5-63.400112.9D119 N571 F585 P591 Q593D119-M587 HydrophobicContact CB-CE 3.69Å; N571-M587 WeakPolarHBondContact O-CA 3.02Å; N571-M587 WeakPolarHBondContact O-CB 3.44Å; N571-M587 WeakPolarHBondContact O-CG 3.26Å; N571-M587 PolarHBondContact O-N 2.8Å; F585-M587 HydrophobicContact CB-SD 4.43Å; M587-P591 WeakPolarHBondContact CE-O 3.26Å; M587-P591 WeakPolarHBondContact O-CA 3.49Å; M587-Q593 HydrophobicContact CE-CG 3.78Å; M587-Q593 VanDerWaalsContact SD-CD 3.57Å; M587-Q593 HydrophobicContact SD-CG 3.41Å; M587-Q593 WeakPolarHBondContact SD-CG 3.31Å; M587-Q593 PolarHBondContact SD-NE2 2.73Å
588N94.8Very high94.2Very high99 Ų9947.1 Ų47.153%0.52928%0.276SS..THydrogen-bonded Turntrans-74.9-33.3171.1-66.7-28.3000111.3N571 D586N571-N588 VanDerWaalsContact CB-OD1 3.22Å; N571-N588 WeakPolarHBondContact CB-OD1 3.35Å; N571-N588 PolarHBondContact ND2-OD1 2.81Å; D586-N588 PolarHBondContact O-N 2.93Å; D586-N588 VanDerWaalsContact OD1-CB 3.3Å; D586-N588 WeakPolarHBondContact OD1-CB 3.47Å; D586-N588 PolarHBondContact OD1-N 3.05Å
589T95.2Very high94.3Very high114 Ų11450.8 Ų50.870%0.69928%0.282SS*.THydrogen-bonded Turntrans-98.6-33.3178.3530000113.3D586D586-T589 PolarHBondContact O-N 2.91Å; D586-T589 PolarHBondContact O-OG1 3.35Å; D586-T589 VanDerWaalsContact O-OG1 3.12Å
590D95.7Very high94.6Very high22 Ų2250.9 Ų50.912%0.11828%0.282CS..  trans-131.671.5-177.8-174.95.4000110.5D586 Y592 Q593 L594 T595D586-D590 WeakPolarHBondContact O-CA 3.3Å; D586-D590 PolarHBondContact O-N 2.64Å; D590-Y592 PolarHBondContact O-N 3.49Å; D590-Y592 PolarHBondContact OD1-N 3.04Å; D590-Q593 PolarHBondContact O-N 3.38Å; D590-Q593 VanDerWaalsContact O-N 3.14Å; D590-Q593 PolarHBondContact OD1-N 3.42Å; D590-Q593 VanDerWaalsContact OD2-C 3.29Å; D590-L594 PolarHBondContact OD1-N 3.43Å; D590-L594 PolarHBondContact OD2-N 3.36Å; D590-T595 PolarHBondContact OD2-N 3.12Å
591P95.4Very high94.9Very high70 Ų7049.8 Ų49.846%0.45527%0.267SS..THydrogen-bonded Turntrans-64.5-9.9-179.726.6-35.5000113.8M587M587-P591 WeakPolarHBondContact CE-O 3.26Å; M587-P591 WeakPolarHBondContact O-CA 3.49Å
592Y95.7Very high94.9Very high100 Ų10053.1 Ų53.139%0.39228%0.283SS..THydrogen-bonded Turntrans-108.42.7179.1-61-68.8000113.6T30 P31 S32 F108 D590 L594T30-Y592 HydrophobicContact CG2-CD1 4.19Å; T30-Y592 HydrophobicContact CG2-CE1 3.8Å; P31-Y592 HydrophobicContact CB-CD2 3.94Å; P31-Y592 HydrophobicContact CB-CE2 4.41Å; P31-Y592 HydrophobicContact CB-CG 4.19Å; P31-Y592 HydrophobicContact CG-CD2 3.63Å; P31-Y592 HydrophobicContact CG-CE2 3.59Å; P31-Y592 HydrophobicContact CG-CG 4.17Å; S32-Y592 WeakPolarHBondContact CB-O 3.47Å; F108-Y592 WeakPolarHBondContact CZ-O 3.38Å; D590-Y592 PolarHBondContact O-N 3.49Å; D590-Y592 PolarHBondContact OD1-N 3.04Å; Y592-L594 PolarHBondContact O-N 3.02Å
593Q96.4Very high94.8Very high2 Ų259.4 Ų59.41%0.00930%0.303CS..  trans61.130172.5-59.2167.3-50.300113.5K41 F108 Y118 L573 F585 M587 D590 T595K41-Q593 WeakPolarHBondContact CE-O 3.41Å; K41-Q593 PolarHBondContact NZ-O 3.1Å; F108-Q593 HydrophobicContact CZ-CB 4.17Å; F108-Q593 VanDerWaalsContact CZ-O 3.3Å; F108-Q593 WeakPolarHBondContact CZ-O 3.44Å; Y118-Q593 VanDerWaalsContact CB-OE1 3.24Å; Y118-Q593 HydrophobicContact CD1-CB 4.38Å; L573-Q593 VanDerWaalsContact CD2-NE2 3.29Å; F585-Q593 HydrophobicContact CB-CG 4.12Å; F585-Q593 HydrophobicContact CD1-CB 3.98Å; F585-Q593 HydrophobicContact CD1-CG 4.48Å; F585-Q593 HydrophobicContact CD2-CB 4.39Å; F585-Q593 HydrophobicContact CD2-CG 4.41Å; F585-Q593 HydrophobicContact CE1-CB 4.27Å; F585-Q593 VanDerWaalsContact CE1-O 3.3Å; F585-Q593 WeakPolarHBondContact CE1-O 3.36Å; F585-Q593 HydrophobicContact CG-CB 4.04Å; F585-Q593 HydrophobicContact CG-CG 4.09Å; M587-Q593 HydrophobicContact CE-CG 3.78Å; M587-Q593 VanDerWaalsContact SD-CD 3.57Å; M587-Q593 HydrophobicContact SD-CG 3.41Å; M587-Q593 WeakPolarHBondContact SD-CG 3.31Å; M587-Q593 PolarHBondContact SD-NE2 2.73Å; D590-Q593 PolarHBondContact O-N 3.38Å; D590-Q593 VanDerWaalsContact O-N 3.14Å; D590-Q593 PolarHBondContact OD1-N 3.42Å; D590-Q593 VanDerWaalsContact OD2-C 3.29Å; Q593-T595 PolarHBondContact O-N 2.91Å
594L95.5Very high94.6Very high38 Ų3860.6 Ų60.620%0.19932%0.316CS..  trans-64-33.4-175.9-56.8-177.3000113.9P31 Y35 K41 F108 D590 Y592P31-L594 HydrophobicContact CB-CD1 4.18Å; Y35-L594 HydrophobicContact CD1-CD2 4.26Å; Y35-L594 HydrophobicContact CD2-CD2 4.47Å; Y35-L594 HydrophobicContact CE1-CB 4.44Å; Y35-L594 WeakPolarHBondContact CE1-O 3.32Å; Y35-L594 HydrophobicContact CG-CD2 4.18Å; K41-L594 PolarHBondContact NZ-O 3.13Å; F108-L594 HydrophobicContact CE1-CD2 4.3Å; D590-L594 PolarHBondContact OD1-N 3.43Å; D590-L594 PolarHBondContact OD2-N 3.36Å; Y592-L594 PolarHBondContact O-N 3.02Å
595T94.1Very high94.4Very high70 Ų7063 Ų6343%0.42933%0.33SS..SBendtrans-133.4122.4-173.5-53.60000112.4F585 D590 Q593 T597F585-T595 WeakPolarHBondContact CD1-O 3.39Å; D590-T595 PolarHBondContact OD2-N 3.12Å; Q593-T595 PolarHBondContact O-N 2.91Å; T595-T597 PolarHBondContact O-N 3.48Å
596N95.9Very high94.3Very high9 Ų964.1 Ų64.15%0.04834%0.336CS..  trans-72.8105.1174.1-178.96.7000111.6D40 L582 E583 Y584 F585 V598 H599D40-N596 HydrophobicContact CB-CB 4.05Å; D40-N596 VanDerWaalsContact O-CB 3.26Å; D40-N596 WeakPolarHBondContact O-CB 3.47Å; D40-N596 PolarHBondContact O-ND2 2.87Å; D40-N596 WeakPolarHBondContact OD2-CB 3.47Å; D40-N596 PolarHBondContact OD2-N 3.01Å; L582-N596 PolarHBondContact O-ND2 2.89Å; E583-N596 WeakPolarHBondContact CA-OD1 3.27Å; Y584-N596 PolarHBondContact N-OD1 2.64Å; Y584-N596 PolarHBondContact O-OD1 2.75Å; F585-N596 HydrophobicContact CE1-CB 4.11Å; F585-N596 HydrophobicContact CZ-CB 4.39Å; N596-V598 VanDerWaalsContact C-N 3.34Å; N596-V598 PolarHBondContact O-N 3.48Å; N596-V598 VanDerWaalsContact OD1-CB 3.26Å; N596-V598 WeakPolarHBondContact OD1-CB 3.49Å; N596-V598 VanDerWaalsContact OD1-CG1 3.25Å; N596-V598 WeakPolarHBondContact OD1-CG1 3.36Å; N596-V598 PolarHBondContact OD1-N 3.02Å; N596-V598 VanDerWaalsContact OD1-N 3.14Å; N596-H599 PolarHBondContact O-ND1 3.37Å
597T94.4Very high94.2Very high38 Ų3867.3 Ų67.323%0.23335%0.353CS..  trans-91.113.1-17852.30000113.7Y584 T595 H599 T600Y584-T597 PolarHBondContact O-N 3.17Å; Y584-T597 PolarHBondContact O-OG1 2.83Å; T595-T597 PolarHBondContact O-N 3.48Å; T597-H599 PolarHBondContact O-N 2.86Å; T597-T600 PolarHBondContact O-N 3.09Å; T597-T600 PolarHBondContact O-OG1 3.09Å
598V93.9Very high94.1Very high25 Ų2573.2 Ų73.215%0.15238%0.38CS..THydrogen-bonded Turntrans-53.5-25.317973.30000114.1L582 N596 L606L582-V598 HydrophobicContact CB-CG2 3.88Å; L582-V598 HydrophobicContact CD1-CG2 4.49Å; N596-V598 VanDerWaalsContact C-N 3.34Å; N596-V598 PolarHBondContact O-N 3.48Å; N596-V598 VanDerWaalsContact OD1-CB 3.26Å; N596-V598 WeakPolarHBondContact OD1-CB 3.49Å; N596-V598 VanDerWaalsContact OD1-CG1 3.25Å; N596-V598 WeakPolarHBondContact OD1-CG1 3.36Å; N596-V598 PolarHBondContact OD1-N 3.02Å; N596-V598 VanDerWaalsContact OD1-N 3.14Å; V598-L606 HydrophobicContact CG2-CD1 4.15Å; V598-L606 HydrophobicContact CG2-CD2 3.81Å
599H91.8Very high94.1Very high144 Ų14469 Ų6967%0.66736%0.358SS*.THydrogen-bonded Turntrans-78.7-17.2178.868.1-86.5000114.3N596 T597N596-H599 PolarHBondContact O-ND1 3.37Å; T597-H599 PolarHBondContact O-N 2.86Å
600T92.1Very high94.1Very high100 Ų10067.2 Ų67.261%0.61334%0.341SS*.THydrogen-bonded Turntrans-94.2-13.6174.366.70000112.7T597T597-T600 PolarHBondContact O-N 3.09Å; T597-T600 PolarHBondContact O-OG1 3.09Å
601V92.3Very high94Very high23 Ų2369.9 Ų69.914%0.13936%0.358CS..SBendtrans-78136.4177.5-175.20000109.9Y584 I605 L606Y584-V601 HydrophobicContact CD1-CG2 3.62Å; Y584-V601 HydrophobicContact CD2-CG2 4.23Å; Y584-V601 HydrophobicContact CE1-CG2 3.82Å; Y584-V601 HydrophobicContact CE2-CG2 4.4Å; Y584-V601 HydrophobicContact CG-CG2 3.86Å; V601-I605 HydrophobicContact CG1-CB 3.89Å; V601-I605 HydrophobicContact CG1-CG2 3.78Å; V601-L606 HydrophobicContact CB-CD2 3.91Å; V601-L606 HydrophobicContact CB-CG 4.11Å; V601-L606 HydrophobicContact CG1-CD2 3.73Å; V601-L606 HydrophobicContact CG1-CG 3.86Å
602E93.3Very high93.9Very high132 Ų13268.3 Ų68.362%0.61735%0.345SS*.  trans-65141.9-179.2-155.2-141.1113.900112G604 I605 L606E602-G604 PolarHBondContact O-N 3.4Å; E602-G604 PolarHBondContact OE1-N 2.94Å; E602-I605 HydrophobicContact CB-CD1 4.09Å; E602-I605 HydrophobicContact CB-CG1 4.24Å; E602-I605 PolarHBondContact O-N 2.9Å; E602-L606 PolarHBondContact O-N 3.05Å
603R91.6Very high93.8Very high179 Ų17963.6 Ų63.668%0.67533%0.326SS*.Hα-helixtrans-57.7-32.3179.3-64.1-179.3-176.7172.51.2112.5N607R603-N607 PolarHBondContact O-N 2.97Å; R603-N607 VanDerWaalsContact O-N 3.1Å; R603-N607 PolarHBondContact O-ND2 3.19Å; R603-N607 VanDerWaalsContact O-ND2 3.15Å
604G92.8Very high93.6Very high26 Ų2667.3 Ų67.327%0.26835%0.345SS..Hα-helixtrans-60.7-46.9173.100000112.6E602 N607 Q608E602-G604 PolarHBondContact O-N 3.4Å; E602-G604 PolarHBondContact OE1-N 2.94Å; G604-N607 PolarHBondContact O-N 3.1Å; G604-Q608 WeakPolarHBondContact O-CG 3.12Å; G604-Q608 PolarHBondContact O-N 3.29Å; G604-Q608 VanDerWaalsContact O-N 3.16Å
605I93.7Very high93.4Very high75 Ų7570.5 Ų70.539%0.38536%0.359SS..Hα-helixtrans-65.5-47.1178-60.2170.8000110.3V601 E602 N607 Q608 L609V601-I605 HydrophobicContact CG1-CB 3.89Å; V601-I605 HydrophobicContact CG1-CG2 3.78Å; E602-I605 HydrophobicContact CB-CD1 4.09Å; E602-I605 HydrophobicContact CB-CG1 4.24Å; E602-I605 PolarHBondContact O-N 2.9Å; I605-N607 VanDerWaalsContact C-N 3.27Å; I605-N607 PolarHBondContact O-N 2.81Å; I605-Q608 WeakPolarHBondContact O-CA 3.27Å; I605-Q608 WeakPolarHBondContact O-CB 3.46Å; I605-Q608 PolarHBondContact O-N 2.98Å; I605-L609 HydrophobicContact CG2-CD1 4.06Å; I605-L609 HydrophobicContact CG2-CG 4.24Å; I605-L609 WeakPolarHBondContact O-CG 3.34Å; I605-L609 PolarHBondContact O-N 3.49Å
606L93.9Very high93.3Very high25 Ų2567.8 Ų67.813%0.13134%0.341CS..Hα-helixtrans-57.1-39.6177.8-66.7176.8000112.5F574 V598 V601 E602 L609 H610F574-L606 HydrophobicContact CD2-CD2 4.46Å; F574-L606 HydrophobicContact CE2-CD2 4.02Å; V598-L606 HydrophobicContact CG2-CD1 4.15Å; V598-L606 HydrophobicContact CG2-CD2 3.81Å; V601-L606 HydrophobicContact CB-CD2 3.91Å; V601-L606 HydrophobicContact CB-CG 4.11Å; V601-L606 HydrophobicContact CG1-CD2 3.73Å; V601-L606 HydrophobicContact CG1-CG 3.86Å; E602-L606 PolarHBondContact O-N 3.05Å; L606-L609 PolarHBondContact O-N 3.06Å; L606-H610 PolarHBondContact O-N 3.33Å
607N94Very high93.1Very high110 Ų11071.4 Ų71.459%0.58835%0.354SS*.Hα-helixtrans-65.8-37.1174.8-70.8-27.8000112.5R603 G604 I605 V611R603-N607 PolarHBondContact O-N 2.97Å; R603-N607 VanDerWaalsContact O-N 3.1Å; R603-N607 PolarHBondContact O-ND2 3.19Å; R603-N607 VanDerWaalsContact O-ND2 3.15Å; G604-N607 PolarHBondContact O-N 3.1Å; I605-N607 VanDerWaalsContact C-N 3.27Å; I605-N607 PolarHBondContact O-N 2.81Å; N607-V611 WeakPolarHBondContact O-CG2 3.28Å; N607-V611 PolarHBondContact O-N 3.2Å; N607-V611 VanDerWaalsContact O-N 3.09Å
608Q93.8Very high92.9Very high137 Ų13774 Ų7464%0.6437%0.374SS*.Hα-helixtrans-66.9-42.1175-68.517210.300111.5G604 I605 V611 Q612G604-Q608 WeakPolarHBondContact O-CG 3.12Å; G604-Q608 PolarHBondContact O-N 3.29Å; G604-Q608 VanDerWaalsContact O-N 3.16Å; I605-Q608 WeakPolarHBondContact O-CA 3.27Å; I605-Q608 WeakPolarHBondContact O-CB 3.46Å; I605-Q608 PolarHBondContact O-N 2.98Å; Q608-V611 PolarHBondContact O-N 3.37Å; Q608-Q612 WeakPolarHBondContact O-CB 3.08Å; Q608-Q612 PolarHBondContact O-N 3.02Å
609L94.8Very high92.8Very high11 Ų1174.3 Ų74.36%0.05838%0.377CS..Hα-helixtrans-63.4-40.2175.8-62.4174.8000111.7L563 F572 F574 Y584 I605 L606 Q612 L613L563-L609 HydrophobicContact CD2-CD2 3.83Å; F572-L609 HydrophobicContact CE2-CD2 3.72Å; F572-L609 HydrophobicContact CZ-CD2 3.56Å; F574-L609 HydrophobicContact CB-CD1 4.28Å; F574-L609 HydrophobicContact CD1-CB 3.67Å; F574-L609 HydrophobicContact CD1-CD1 4.43Å; F574-L609 HydrophobicContact CD2-CD1 4.29Å; F574-L609 HydrophobicContact CE1-CB 3.76Å; F574-L609 HydrophobicContact CG-CB 4.17Å; F574-L609 HydrophobicContact CG-CD1 4.08Å; F574-L609 HydrophobicContact CZ-CB 4.35Å; Y584-L609 HydrophobicContact CD2-CD1 4.09Å; Y584-L609 HydrophobicContact CE2-CD1 3.9Å; I605-L609 HydrophobicContact CG2-CD1 4.06Å; I605-L609 HydrophobicContact CG2-CG 4.24Å; I605-L609 WeakPolarHBondContact O-CG 3.34Å; I605-L609 PolarHBondContact O-N 3.49Å; L606-L609 PolarHBondContact O-N 3.06Å; L609-Q612 PolarHBondContact O-N 3.24Å; L609-L613 VanDerWaalsContact O-CB 3.26Å; L609-L613 WeakPolarHBondContact O-CB 3.26Å; L609-L613 PolarHBondContact O-N 3.12Å
610H94.5Very high92.7Very high75 Ų7573.7 Ų73.735%0.34737%0.374SS..Hα-helixtrans-59-47.7172.2177.973.4000112.1E576 L606 L613 M614E576-H610 WeakPolarHBondContact OE1-CB 3.15Å; E576-H610 IonicContact OE1-CE1 2.77Å; E576-H610 IonicContact OE1-CG 2.63Å; E576-H610 IonicContact OE1-ND1 2.63Å; E576-H610 PolarHBondContact OE1-ND1 3.1Å; E576-H610 IonicContact OE2-CE1 3.61Å; E576-H610 PolarHBondContact OE2-CE1 2.99Å; E576-H610 IonicContact OE2-ND1 3.89Å; E576-H610 PolarHBondContact OE2-ND1 2.8Å; L606-H610 PolarHBondContact O-N 3.33Å; H610-L613 PolarHBondContact O-N 2.97Å; H610-M614 WeakPolarHBondContact O-CB 3.32Å; H610-M614 VanDerWaalsContact O-CG 3.26Å; H610-M614 WeakPolarHBondContact O-CG 3.46Å; H610-M614 PolarHBondContact O-N 3.14Å
611V94.1Very high92.6Very high78 Ų7869 Ų6947%0.47335%0.346SS..Hα-helixtrans-61.8-48.8178.3170.90000110.8N607 Q608 L613 M614 E615N607-V611 WeakPolarHBondContact O-CG2 3.28Å; N607-V611 PolarHBondContact O-N 3.2Å; N607-V611 VanDerWaalsContact O-N 3.09Å; Q608-V611 PolarHBondContact O-N 3.37Å; V611-L613 VanDerWaalsContact C-N 3.31Å; V611-L613 PolarHBondContact O-N 2.73Å; V611-M614 PolarHBondContact O-N 3.34Å; V611-M614 VanDerWaalsContact O-N 3.08Å; V611-E615 HydrophobicContact CG1-CG 4.45Å; V611-E615 WeakPolarHBondContact O-CG 3.38Å; V611-E615 PolarHBondContact O-N 2.91Å
612Q93.1Very high92.3Very high38 Ų3871.2 Ų71.218%0.17835%0.352CS..Hα-helixtrans-62.3-36.2178.7-172.7176.4-8.200112.6T194 L563 Q608 L609 L616T194-Q612 PolarHBondContact OG1-NE2 2.85Å; L563-Q612 HydrophobicContact CD1-CG 4.15Å; L563-Q612 HydrophobicContact CD2-CB 4.24Å; L563-Q612 HydrophobicContact CD2-CG 4.13Å; Q608-Q612 WeakPolarHBondContact O-CB 3.08Å; Q608-Q612 PolarHBondContact O-N 3.02Å; L609-Q612 PolarHBondContact O-N 3.24Å; Q612-L616 PolarHBondContact O-N 2.84Å
613L93.6Very high91.9Very high0 Ų072.4 Ų72.40%036%0.355CS..Hα-helixtrans-63.9-43.4172.7-177.268.9000111.4L196 W561 L563 F574 E576 L609 H610 V611 L616 R617L196-L613 HydrophobicContact CD1-CD1 3.65Å; W561-L613 HydrophobicContact CB-CD1 4.09Å; W561-L613 HydrophobicContact CB-CD2 4.08Å; W561-L613 HydrophobicContact CB-CG 4.29Å; L563-L613 HydrophobicContact CB-CD1 4.2Å; F574-L613 HydrophobicContact CE1-CD2 4.37Å; E576-L613 HydrophobicContact CB-CD2 3.95Å; E576-L613 HydrophobicContact CG-CD2 3.55Å; L609-L613 VanDerWaalsContact O-CB 3.26Å; L609-L613 WeakPolarHBondContact O-CB 3.26Å; L609-L613 PolarHBondContact O-N 3.12Å; H610-L613 PolarHBondContact O-N 2.97Å; V611-L613 VanDerWaalsContact C-N 3.31Å; V611-L613 PolarHBondContact O-N 2.73Å; L613-L616 PolarHBondContact O-N 2.04Å; L613-R617 WeakPolarHBondContact O-CB 3.38Å; L613-R617 WeakPolarHBondContact O-CG 3.07Å; L613-R617 PolarHBondContact O-N 2.98Å
614M92.1Very high91.6Very high81 Ų8169.6 Ų69.640%0.39935%0.349SS..Hα-helixtrans-71.4-31179.4-68.3-67.6-77.900112.8H610 V611 R617 S618H610-M614 WeakPolarHBondContact O-CB 3.32Å; H610-M614 VanDerWaalsContact O-CG 3.26Å; H610-M614 WeakPolarHBondContact O-CG 3.46Å; H610-M614 PolarHBondContact O-N 3.14Å; V611-M614 PolarHBondContact O-N 3.34Å; V611-M614 VanDerWaalsContact O-N 3.08Å; M614-R617 PolarHBondContact O-N 3.36Å; M614-R617 PolarHBondContact SD-NH1 3.01Å; M614-S618 WeakPolarHBondContact O-CB 3.06Å; M614-S618 PolarHBondContact O-N 3.22Å; M614-S618 PolarHBondContact O-OG 3.49Å
615E92.1Very high91.4Very high105 Ų10569.2 Ų69.249%0.49134%0.343SS..Hα-helixtrans-60.9-54.8167.7-72.9170.6176.800110.9V611 R617 S618 C619V611-E615 HydrophobicContact CG1-CG 4.45Å; V611-E615 WeakPolarHBondContact O-CG 3.38Å; V611-E615 PolarHBondContact O-N 2.91Å; E615-R617 PolarHBondContact O-N 3.12Å; E615-S618 CarbonylContact O-C 3.38Å; E615-S618 PolarHBondContact O-N 3.3Å; E615-S618 PolarHBondContact O-OG 2.99Å; E615-C619 PolarHBondContact O-N 2.88Å
616L92.1Very high90.8Very high13 Ų1366 Ų667%0.06833%0.327CS..Hα-helixtrans-64.9-20.3178.5-69.7-177000114T194 L196 L563 Q612 L613 C619 P627T194-L616 HydrophobicContact CG2-CD1 4.27Å; L196-L616 HydrophobicContact CB-CB 4.17Å; L563-L616 HydrophobicContact CD1-CD1 3.56Å; Q612-L616 PolarHBondContact O-N 2.84Å; L613-L616 PolarHBondContact O-N 2.04Å; L616-C619 PolarHBondContact O-SG 3.45Å; L616-P627 HydrophobicContact CD2-CG 4.19Å
617R90.9Very high89.6Confident85 Ų8566.8 Ų66.832%0.32133%0.333SS..THydrogen-bonded Turntrans-84.2-9.9172.4-73.2176.668.6-163.5-0114.6L196 W561 L613 M614 E615L196-R617 HydrophobicContact CD1-CG 3.83Å; L196-R617 HydrophobicContact CD2-CG 3.75Å; L196-R617 HydrophobicContact CG-CG 4.49Å; W561-R617 HydrophobicContact CG-CG 4.45Å; L613-R617 WeakPolarHBondContact O-CB 3.38Å; L613-R617 WeakPolarHBondContact O-CG 3.07Å; L613-R617 PolarHBondContact O-N 2.98Å; M614-R617 PolarHBondContact O-N 3.36Å; M614-R617 PolarHBondContact SD-NH1 3.01Å; E615-R617 PolarHBondContact O-N 3.12Å
618S90.9Very high88.3Confident92 Ų9270 Ų7064%0.64334%0.337SS*.THydrogen-bonded Turntrans-122.5-2.8-178.457.10000113.9M614 E615M614-S618 WeakPolarHBondContact O-CB 3.06Å; M614-S618 PolarHBondContact O-N 3.22Å; M614-S618 PolarHBondContact O-OG 3.49Å; E615-S618 CarbonylContact O-C 3.38Å; E615-S618 PolarHBondContact O-N 3.3Å; E615-S618 PolarHBondContact O-OG 2.99Å
619C90.8Very high86.8Confident31 Ų3164.8 Ų64.821%0.20932%0.315CS..  trans-62.4156.9171.873.80000112.3E615 L616 Q624 C625E615-C619 PolarHBondContact O-N 2.88Å; L616-C619 PolarHBondContact O-SG 3.45Å; C619-Q624 HydrophobicContact CB-CB 3.75Å; C619-C625 VanDerWaalsContact C-SG 3.5Å; C619-C625 HydrophobicContact CB-CB 3.99Å; C619-C625 WeakPolarHBondContact CB-SG 3.36Å; C619-C625 WeakPolarHBondContact SG-CA 3.18Å; C619-C625 WeakPolarHBondContact SG-CB 3.46Å; C619-C625 CovalentContact SG-SG 2.04Å; C619-C625 PolarHBondContact SG-SG 2.94Å
620Q90.8Very high85Confident132 Ų13272 Ų7262%0.61735%0.345SS*.  trans-141.6131.1166-173.4-179.9-1.600110.4Q624Q620-Q624 PolarHBondContact O-OE1 3.05Å
621G89.6Confident82.7Confident1 Ų175.3 Ų75.31%0.0137%0.366CS..SBendtrans78.4154.717800000113.4P162 V164 D165 K623 Q624 C625P162-G621 VanDerWaalsContact O-CA 3.3Å; P162-G621 WeakPolarHBondContact O-CA 3.34Å; V164-G621 CarbonylContact O-C 3.59Å; D165-G621 WeakPolarHBondContact OD1-CA 3.34Å; D165-G621 PolarHBondContact OD1-N 3.15Å; G621-K623 PolarHBondContact O-N 3.15Å; G621-Q624 PolarHBondContact O-N 2.88Å; G621-C625 PolarHBondContact O-N 3.24Å
622Y85.9Confident80.2Confident69 Ų6975.2 Ų75.227%0.27136%0.362SS..THydrogen-bonded Turntrans-58.9-19.6-170.371.8-98.3000115.1T160 V164 D165 G166 K167 N626T160-Y622 HydrophobicContact CG2-CD1 4.32Å; T160-Y622 HydrophobicContact CG2-CE1 4.45Å; V164-Y622 WeakPolarHBondContact O-CB 3.33Å; V164-Y622 PolarHBondContact O-N 3.36Å; D165-Y622 WeakPolarHBondContact O-CA 3.28Å; G166-Y622 VanDerWaalsContact O-CB 3.26Å; G166-Y622 WeakPolarHBondContact O-CB 3.43Å; K167-Y622 WeakPolarHBondContact CE-O 3.28Å; K167-Y622 HydrophobicContact CG-CD2 4.28Å; K167-Y622 HydrophobicContact CG-CG 4.37Å; Y622-N626 WeakPolarHBondContact CA-ND2 3.47Å; Y622-N626 WeakPolarHBondContact O-CB 3.46Å; Y622-N626 PolarHBondContact O-ND2 3.25Å
623K84.4Confident77.5Confident157 Ų15780.3 Ų80.368%0.68339%0.391SS*.THydrogen-bonded Turntrans-74.3-29.4177.1-64.2-176179.71790112.7G621G621-K623 PolarHBondContact O-N 3.15Å
624Q86.5Confident74.9Confident120 Ų12085.5 Ų85.556%0.56142%0.422SS*.THydrogen-bonded Turntrans-99-46.7177.4-59.8-177.31.100110.9C619 Q620 G621 N626C619-Q624 HydrophobicContact CB-CB 3.75Å; Q620-Q624 PolarHBondContact O-OE1 3.05Å; G621-Q624 PolarHBondContact O-N 2.88Å; Q624-N626 PolarHBondContact O-N 3.26Å; Q624-N626 VanDerWaalsContact O-N 3.11Å
625C87.1Confident72.2Confident19 Ų1985.1 Ų85.113%0.12844%0.439CS..SBendtrans-74.2-0.4-174-61.40000115.2D165 C619 G621D165-C625 HydrophobicContact CB-CB 4.04Å; D165-C625 PolarHBondContact OD1-SG 3.14Å; C619-C625 VanDerWaalsContact C-SG 3.5Å; C619-C625 HydrophobicContact CB-CB 3.99Å; C619-C625 WeakPolarHBondContact CB-SG 3.36Å; C619-C625 WeakPolarHBondContact SG-CA 3.18Å; C619-C625 WeakPolarHBondContact SG-CB 3.46Å; C619-C625 CovalentContact SG-SG 2.04Å; C619-C625 PolarHBondContact SG-SG 2.94Å; G621-C625 PolarHBondContact O-N 3.24Å
626N81.6Confident69.3Low8 Ų887 Ų874%0.04345%0.452CS..SBendtrans-132.677.1173.6-57-92.2000109.3D165 K167 R192 Y622 Q624D165-N626 PolarHBondContact O-ND2 3.15Å; K167-N626 HydrophobicContact CD-CB 4.13Å; K167-N626 PolarHBondContact NZ-O 3.3Å; R192-N626 HydrophobicContact CB-CB 4.35Å; R192-N626 WeakPolarHBondContact CD-OD1 3.35Å; R192-N626 PolarHBondContact NE-OD1 3.08Å; R192-N626 VanDerWaalsContact NE-OD1 3.11Å; R192-N626 PolarHBondContact NH1-OD1 3.12Å; Y622-N626 WeakPolarHBondContact CA-ND2 3.47Å; Y622-N626 WeakPolarHBondContact O-CB 3.46Å; Y622-N626 PolarHBondContact O-ND2 3.25Å; Q624-N626 PolarHBondContact O-N 3.26Å; Q624-N626 VanDerWaalsContact O-N 3.11Å
627P69.2Low66.6Low40 Ų4096.3 Ų96.326%0.2649%0.492SS..PPolyproline II helixtrans-53.8151.8173.624.1-34.4000110.7L616L616-P627 HydrophobicContact CD2-CG 4.19Å
628R66Low63.7Low178 Ų17899.1 Ų99.167%0.67251%0.514SS*.PPolyproline II helixtrans-76.6146.9172.3-66-177.1-179.9174.61109.4I190 K630I190-R628 HydrophobicContact CG2-CB 4.45Å; I190-R628 HydrophobicContact CG2-CG 4.1Å; R628-K630 PolarHBondContact O-N 3.11Å
629P62.8Low60.8Low27 Ų2799 Ų9918%0.17553%0.527CS..PPolyproline II helixtrans-56.8122.5169.5-23.734.6000109.7W191 D193 N631 L632W191-P629 VanDerWaalsContact O-CD 3.25Å; W191-P629 WeakPolarHBondContact O-CD 3.24Å; W191-P629 WeakPolarHBondContact O-CG 3.29Å; D193-P629 HydrophobicContact CB-CG 4.36Å; D193-P629 WeakPolarHBondContact OD2-CB 3.42Å; P629-N631 PolarHBondContact O-N 3.43Å; P629-L632 PolarHBondContact O-N 3.41Å
630K56.2Low57.8Low162 Ų162101 Ų10170%0.70455%0.553SS**THydrogen-bonded Turntrans-66-2.6-169.1-64.6-175.2178.6-179.40114.7R628R628-K630 PolarHBondContact O-N 3.11Å
631N46.8Very low54.8Low145 Ų145100.6 Ų100.678%0.77556%0.564SS**THydrogen-bonded Turntrans-101.33.7-178.4-65-15.4000114.2P629P629-N631 PolarHBondContact O-N 3.43Å
632L41.6Very low51.9Low77 Ų77111 Ų11140%0.40361%0.605SS.*  trans-115.533.3-173.8-79.6172.1000115P629 V634P629-L632 PolarHBondContact O-N 3.41Å; L632-V634 PolarHBondContact O-N 2.65Å
633D37.1Very low49.2Very low145 Ų145115.1 Ų115.178%0.77563%0.632SS**  trans-74.168171.9-86-21.5000113G635D633-G635 PolarHBondContact O-N 3.14Å; D633-G635 VanDerWaalsContact O-N 3.11Å
634V38.7Very low46.7Very low108 Ų108114.8 Ų114.866%0.65564%0.637SS**  trans-74.194.7156.8-178.60000107.1L632 N636L632-V634 PolarHBondContact O-N 2.65Å; V634-N636 PolarHBondContact O-N 2.7Å; V634-N636 VanDerWaalsContact O-N 3.1Å
635G35.2Very low44Very low73 Ų73118.3 Ų118.375%0.75365%0.653SS**  trans-53.2110.2-166.200000115.3D633D633-G635 PolarHBondContact O-N 3.14Å; D633-G635 VanDerWaalsContact O-N 3.11Å
636N30.2Very low41.3Very low144 Ų144129 Ų12977%0.7769%0.69SS**  trans-92.6123.2161.7-123.847.7000108.1V634 D638V634-N636 PolarHBondContact O-N 2.7Å; V634-N636 VanDerWaalsContact O-N 3.1Å; N636-D638 PolarHBondContact O-N 3.46Å; N636-D638 VanDerWaalsContact O-N 3.08Å
637K35.8Very low38.7Very low210 Ų210136.7 Ų136.791%0.91373%0.728SS**  trans-78.987.6177.1-72.8-175.9178.3-179.60111
638D31.6Very low36.7Very low144 Ų144142.3 Ų142.377%0.7776%0.755SS**  trans-133.1110.3156.4-76.6-60.3000107.5N636N636-D638 PolarHBondContact O-N 3.46Å; N636-D638 VanDerWaalsContact O-N 3.08Å
639G29.3Very low35Very low89 Ų89141.9 Ų141.992%0.91877%0.765SS**  trans-83.5136-167.200000113.7
640G26.7Very low33.5Very low74 Ų74150.4 Ų150.476%0.76380%0.8SS**  trans-173.494.2177.300000114.8
641S27.8Very low32.2Very low122 Ų122150.4 Ų150.485%0.85381%0.807SS**  trans78147.5175.3-158.60000117.3
642Y30.6Very low31.4Very low220 Ų220150.3 Ų150.386%0.86381%0.811SS**  trans-84142.7-175.8-62.2-102.4000111.4
643D28.8Very low30.9Very low155 Ų155152.1 Ų152.183%0.82983%0.828SS**  trans-117.5136158.7-166.2-11.7000108.4
644L32.3Very low30.5Very low151 Ų151151.7 Ų151.779%0.79184%0.835SS**  trans-132.538.8-165.1-162.7101.8000113.1
645H29.1Very low30.2Very low193 Ų193152.4 Ų152.489%0.89484%0.844SS**  trans-136.476.4165.1-107.544.5000112.2
646R31Very low29.9Very low244 Ų244153 Ų15392%0.92184%0.842SS**  trans-122.294176-173.9-169.9-172.2-147.33.1111.5
647M27.1Very low30Very low169 Ų169152 Ų15283%0.83384%0.843SS**  trans-168.6158.6160-96.8-102.584.100110.2
648L27.4Very low29.7Very low159 Ų159150.2 Ų150.283%0.83284%0.843SS**  trans65.869.4166.7-65.4159.2000117.8
649L29.9Very low29.7Very low168 Ų168149.9 Ų149.988%0.8885%0.846SS**  trans-130.395.8145.3-94.9174000109.1
650F31.8Very low29.7Very low207 Ų207151.5 Ų151.591%0.90884%0.844SS**  trans-156.3147.3169.2-90.6-68.9000110.3
651L28.8Very low29.8Very low161 Ų161159.6 Ų159.684%0.84385%0.851SS**  trans70.688.2170.5-57.3173.6000118.7
652V28.5Very low29.9Very low143 Ų143158 Ų15887%0.86785%0.845SS**  -134131.4126.5-177.50000107.2
653P32.7Very low29.8Very low116 Ų116156.6 Ų156.675%0.75385%0.849SS**  trans-90134.5-175.933.3-33.2000113.3
654C28.2Very low29.8Very low136 Ų136156.1 Ų156.192%0.91985%0.851SS**  trans-85.8111.4162.6-78.60000110.4
655S30.9Very low29.7Very low123 Ų123153.3 Ų153.386%0.8684%0.844SS**  trans-85.9108.2170.355.50000110.9
656A28.8Very low29.8Very low85 Ų85151.6 Ų151.670%0.70284%0.842SS**  trans-114.9126.4168.900000109.5
657P32.4Very low29.7Very low122 Ų122145 Ų14579%0.79284%0.839SS**  trans-76.1134.5177.430.6-33000110.7
658L30.9Very low30Very low173 Ų173142.2 Ų142.291%0.90684%0.836SS**  trans-74.7131.1166.2-68.898.1000109.6
659T31.1Very low30.5Very low137 Ų137147.9 Ų147.984%0.8486%0.855SS**  trans-111.7131.5160.246.40000109.3
660S29.2Very low30.5Very low124 Ų124146.9 Ų146.987%0.86785%0.853SS**  trans-77.6142.4-172.4-169.10000111.9A662S660-A662 PolarHBondContact O-N 3.14Å
661R29.6Very low30.4Very low244 Ų244143.7 Ų143.792%0.92185%0.851SS**  trans-9684.7-178.9-162.9179.8-165.9179.44.6110.1
662A28.6Very low30.5Very low89 Ų89142.7 Ų142.774%0.73685%0.851SS**  trans-74138.117300000111.2S660S660-A662 PolarHBondContact O-N 3.14Å
663M29.1Very low30.7Very low189 Ų189142.7 Ų142.793%0.93185%0.85SS**  trans-88.8136.2167-71.6174159.700109.7
664V29.7Very low30.5Very low146 Ų146144.4 Ų144.489%0.88586%0.856SS**  trans-139.9139.1157.8-177.50000107.3
665S29Very low30.7Very low92 Ų92144.9 Ų144.964%0.64385%0.852SS**  trans-95.2166.9-177.5-430000112.4
666D31.5Very low30.7Very low157 Ų157146.5 Ų146.584%0.8485%0.851SS**  trans43.4115.4148.3-48.5-36.3000120.4
667A28.7Very low30.8Very low104 Ų104151.2 Ų151.286%0.8686%0.863SS**  -167.2143.6123.700000112
668S34.4Very low30.7Very low111 Ų111153.7 Ų153.778%0.77687%0.869SS**  trans-73.7143.4177.8-36.20000113.3
669F36.6Very low30.7Very low278 Ų278151.9 Ų151.9100%1.21987%0.865SS**  -162.80108.9-119.9-79000111.8

Retrieved 669 of 669 residues in 438.9 ms (Link to these results)