A0A087WWY1_HUMAN Loading...

Phosphodiesterase 4D interacting protein

AlphaFold DB , UniProt , Accession A0A087WWY1, Species HUMAN (Homo sapiens, Human), Gene PDE4DIP, Length 114 aa.

						>A0A087WWY1_HUMAN|A0A087WWY1|PDE4DIP
MEQTWTRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRG
					

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.6	Very low	47.1	Very low	238 Å²	238	162.2 Å²	162.2	100%	1.172	76%	0.763	S	S	*	*				0	92.1	0	-66.7	175.3	-172.5	0	0	105.3
2	E	42.4	Very low	47.3	Very low	187 Å²	187	161.3 Å²	161.3	87%	0.874	76%	0.758	S	S	*	*			trans	-97.3	127	-176.7	-66.4	-95.5	138.6	0	0	107.4	T4	E2-T4 PolarHBondContact O-N 3.29Å
3	Q	43.7	Very low	47.2	Very low	154 Å²	154	159.8 Å²	159.8	72%	0.72	76%	0.758	S	S	*	*			trans	-66.8	122	-170.8	-64.8	-80.7	61.8	0	0	111.1	W5	Q3-W5 VanDerWaalsContact O-CD1 3.29Å; Q3-W5 PolarHBondContact O-N 3.24Å
4	T	49.3	Very low	47.7	Very low	76 Å²	76	157.9 Å²	157.9	47%	0.466	76%	0.755	S	S	.	*			trans	-85.1	83.1	178.4	50.9	0	0	0	0	110	E2 T6 R7	E2-T4 PolarHBondContact O-N 3.29Å; T4-T6 PolarHBondContact O-N 3.43Å; T4-R7 PolarHBondContact O-N 2.8Å; T4-R7 WeakPolarHBondContact OG1-CB 3.26Å
5	W	50.4	Low	47.9	Very low	217 Å²	217	150.1 Å²	150.1	82%	0.822	73%	0.733	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61	-4.7	177.3	-58.5	94.3	0	0	0	114.6	Q3	Q3-W5 VanDerWaalsContact O-CD1 3.29Å; Q3-W5 PolarHBondContact O-N 3.24Å
6	T	53	Low	48	Very low	136 Å²	136	151.8 Å²	151.8	83%	0.834	74%	0.739	S	S	*	*	T	Hydrogen-bonded Turn	trans	-96.3	-8.1	176.7	-36.2	0	0	0	0	113	T4	T4-T6 PolarHBondContact O-N 3.43Å
7	R	46	Very low	48.1	Very low	184 Å²	184	153.1 Å²	153.1	69%	0.694	75%	0.746	S	S	*	*	S	Bend	trans	-99.4	-4	-170.1	-137.7	167.5	98.7	139.6	5.1	115.5	T4	T4-R7 PolarHBondContact O-N 2.8Å; T4-R7 WeakPolarHBondContact OG1-CB 3.26Å
8	D	45.4	Very low	48.2	Very low	129 Å²	129	149.9 Å²	149.9	69%	0.69	74%	0.737	S	S	*	*	S	Bend	trans	-107.1	4.9	-174.8	-56.5	-23.6	0	0	0	113
9	Y	43.9	Very low	48.2	Very low	211 Å²	211	147.1 Å²	147.1	83%	0.827	73%	0.731	S	S	*	*	S	Bend	trans	-88.7	-9.3	173.6	-118.5	-84.4	0	0	0	113.6
10	F	50.6	Low	48.4	Very low	203 Å²	203	150.2 Å²	150.2	89%	0.89	73%	0.734	S	S	*	*	S	Bend	trans	-142.5	4.1	-169.6	-82.3	-77.2	0	0	0	115.3
11	A	55.1	Low	48.8	Very low	49 Å²	49	148.2 Å²	148.2	41%	0.405	73%	0.731	S	S	.	*	S	Bend	trans	-125.2	129.6	179.9	0	0	0	0	0	109.5
12	E	50	Low	49.6	Very low	151 Å²	151	141.5 Å²	141.5	71%	0.706	71%	0.707	S	S	*	*			trans	79.5	67.3	175.5	-33	-54.8	114.7	0	0	116.6
13	D	46.1	Very low	50.2	Low	142 Å²	142	139.9 Å²	139.9	76%	0.759	70%	0.7	S	S	*	*			trans	-122.9	81.2	136.8	-172.4	31.3	0	0	0	107.5	G15	D13-G15 PolarHBondContact O-N 2.81Å; D13-G15 VanDerWaalsContact O-N 3.17Å
14	D	54.2	Low	50.3	Low	134 Å²	134	139.5 Å²	139.5	72%	0.717	71%	0.708	S	S	*	*			trans	-81.7	29.5	174.2	-42.3	-26.7	0	0	0	110.6	E16	D14-E16 PolarHBondContact O-N 2.85Å
15	G	50.7	Low	50.4	Low	41 Å²	41	140.6 Å²	140.6	42%	0.423	72%	0.724	S	S	.	*			trans	-74.6	107.8	166.7	0	0	0	0	0	108.7	D13 M17	D13-G15 PolarHBondContact O-N 2.81Å; D13-G15 VanDerWaalsContact O-N 3.17Å; G15-M17 PolarHBondContact O-N 2.89Å
16	E	48.8	Very low	50.7	Low	176 Å²	176	133.8 Å²	133.8	82%	0.822	72%	0.715	S	S	*	*			trans	-25.8	102.9	167.9	-78.2	-173.9	133.6	0	0	112.7	D14 V18	D14-E16 PolarHBondContact O-N 2.85Å; E16-V18 HydrophobicContact CB-CG2 4.18Å; E16-V18 PolarHBondContact O-N 3.17Å
17	M	50.8	Low	50.3	Low	175 Å²	175	136.4 Å²	136.4	86%	0.862	72%	0.715	S	S	*	*			trans	-74.9	76.1	161.1	-74.8	-96.1	-170.4	0	0	106.8	G15 P19	G15-M17 PolarHBondContact O-N 2.89Å; M17-P19 VanDerWaalsContact O-CD 3.26Å; M17-P19 WeakPolarHBondContact O-CD 3.47Å; M17-P19 VanDerWaalsContact O-N 3.11Å
18	V	49.6	Very low	50.5	Low	95 Å²	95	136.4 Å²	136.4	58%	0.576	73%	0.727	S	S	*	*			trans	-53.6	119.4	163.9	179.9	0	0	0	0	105.8	E16 R20	E16-V18 HydrophobicContact CB-CG2 4.18Å; E16-V18 PolarHBondContact O-N 3.17Å; V18-R20 PolarHBondContact O-N 3.13Å
19	P	47.4	Very low	50.5	Low	97 Å²	97	134.8 Å²	134.8	63%	0.63	73%	0.727	S	S	*	*			trans	-63.2	103.1	172.9	22.6	-27.8	0	0	0	107.2	M17 T21	M17-P19 VanDerWaalsContact O-CD 3.26Å; M17-P19 WeakPolarHBondContact O-CD 3.47Å; M17-P19 VanDerWaalsContact O-N 3.11Å; P19-T21 HydrophobicContact CB-CG2 4.11Å; P19-T21 PolarHBondContact O-N 3.12Å
20	R	52.7	Low	50.2	Low	208 Å²	208	131.4 Å²	131.4	79%	0.785	72%	0.723	S	S	*	*			trans	-70.7	55.4	159	-76.8	-169.7	84.6	111.1	1.2	109.2	V18 S22 H23	V18-R20 PolarHBondContact O-N 3.13Å; R20-S22 PolarHBondContact O-N 3.48Å; R20-H23 PolarHBondContact NH2-NE2 3.32Å
21	T	57.9	Low	50.5	Low	109 Å²	109	128.5 Å²	128.5	67%	0.669	72%	0.722	S	S	*	*			trans	-75.2	110.6	151.7	63.2	0	0	0	0	105.3	P19	P19-T21 HydrophobicContact CB-CG2 4.11Å; P19-T21 PolarHBondContact O-N 3.12Å
22	S	52.7	Low	50.3	Low	98 Å²	98	134.3 Å²	134.3	69%	0.685	74%	0.738	S	S	*	*			trans	155.2	53.3	151.3	-70.9	0	0	0	0	112.2	R20	R20-S22 PolarHBondContact O-N 3.48Å
23	H	55.5	Low	50.5	Low	153 Å²	153	134 Å²	134	71%	0.708	74%	0.741	S	S	*	*	S	Bend	trans	-140.1	42.7	153.8	-57	-64.7	0	0	0	111.3	R20	R20-H23 PolarHBondContact NH2-NE2 3.32Å
24	T	46.6	Very low	50.5	Low	146 Å²	146	138.5 Å²	138.5	90%	0.896	75%	0.747	S	S	*	*			trans	-135.8	51.5	167.4	-35.9	0	0	0	0	110
25	A	51.7	Low	50.3	Low	98 Å²	98	135.4 Å²	135.4	81%	0.81	75%	0.747	S	S	*	*			trans	-129.1	29.8	175.8	0	0	0	0	0	112.2
26	A	55.2	Low	50.1	Low	75 Å²	75	139.4 Å²	139.4	62%	0.62	77%	0.765	S	S	*	*	S	Bend	trans	-110.5	-6.2	-177.7	0	0	0	0	0	115.6
27	F	46	Very low	50.4	Low	190 Å²	190	136.5 Å²	136.5	83%	0.833	76%	0.762	S	S	*	*			trans	-138.8	29.8	-179.4	-57.6	-70.3	0	0	0	115	S29	F27-S29 PolarHBondContact O-N 3.26Å; F27-S29 VanDerWaalsContact O-N 3.13Å
28	L	50	Low	50.1	Low	184 Å²	184	134.7 Å²	134.7	96%	0.963	76%	0.761	S	S	*	*			trans	-81.8	70	152.7	-75.8	174	0	0	0	108.1
29	S	44.9	Very low	50	Low	96 Å²	96	136.9 Å²	136.9	67%	0.671	77%	0.765	S	S	*	*			trans	-116.2	102.8	162.9	49.3	0	0	0	0	107.9	F27	F27-S29 PolarHBondContact O-N 3.26Å; F27-S29 VanDerWaalsContact O-N 3.13Å
30	D	38.3	Very low	50.5	Low	140 Å²	140	138.3 Å²	138.3	75%	0.749	78%	0.777	S	S	*	*			trans	74.2	92.8	151.8	-150.2	27.1	0	0	0	118.4	K32	D30-K32 PolarHBondContact O-N 3.4Å
31	T	55.9	Low	50.3	Low	141 Å²	141	134.8 Å²	134.8	87%	0.865	77%	0.769	S	S	*	*			trans	-71.1	91.6	155.8	52	0	0	0	0	109.4
32	K	51.5	Low	49.6	Very low	172 Å²	172	134.9 Å²	134.9	75%	0.748	77%	0.765	S	S	*	*			trans	-150.9	125.9	155.9	-150.8	160.7	175.3	178.2	0	111.5	D30	D30-K32 PolarHBondContact O-N 3.4Å
33	D	54.5	Low	49.4	Very low	143 Å²	143	142.5 Å²	142.5	77%	0.765	78%	0.778	S	S	*	*			trans	79.1	94.8	168.9	-109.7	58.4	0	0	0	117.1
34	R	45.4	Very low	49.3	Very low	237 Å²	237	145.4 Å²	145.4	89%	0.894	78%	0.783	S	S	*	*				158.9	111.1	100.3	-167.7	164.4	-166.3	138.1	-0.5	113.4
35	G	50.8	Low	49	Very low	69 Å²	69	143.5 Å²	143.5	71%	0.711	78%	0.776	S	S	*	*			trans	86.2	149.1	141.6	0	0	0	0	0	119.5
36	P	45.3	Very low	49.1	Very low	125 Å²	125	141.8 Å²	141.8	81%	0.812	77%	0.767	S	S	*	*			trans	-79.5	163.5	-161.3	34.4	-35.4	0	0	0	113.9
37	P	56.1	Low	48.6	Very low	115 Å²	115	146.5 Å²	146.5	75%	0.747	78%	0.777	S	S	*	*			trans	-75.4	171.9	-177.7	35	-35.3	0	0	0	110.7
38	V	44.6	Very low	49	Very low	138 Å²	138	146.2 Å²	146.2	84%	0.836	78%	0.775	S	S	*	*			trans	109	109.5	173.8	-179.1	0	0	0	0	111.7
39	Q	47.3	Very low	48.9	Very low	141 Å²	141	142.9 Å²	142.9	66%	0.659	76%	0.762	S	S	*	*				-176.9	94.9	108.9	-166.7	171.6	-20.2	0	0	110	Q41	Q39-Q41 HydrophobicContact CG-CB 3.9Å; Q39-Q41 HydrophobicContact CG-CG 3.86Å; Q39-Q41 PolarHBondContact O-N 3.41Å
40	S	56.8	Low	49.5	Very low	127 Å²	127	143.5 Å²	143.5	89%	0.888	76%	0.764	S	S	*	*			trans	-55.7	101.6	152	-64.4	0	0	0	0	108.2
41	Q	48.7	Very low	50.1	Low	134 Å²	134	144.7 Å²	144.7	63%	0.626	76%	0.763	S	S	*	*			trans	-170	142.3	167.7	-79.8	-134.7	3.5	0	0	105.2	Q39	Q39-Q41 HydrophobicContact CG-CB 3.9Å; Q39-Q41 HydrophobicContact CG-CG 3.86Å; Q39-Q41 PolarHBondContact O-N 3.41Å
42	I	43.2	Very low	49.8	Very low	111 Å²	111	143.8 Å²	143.8	57%	0.569	76%	0.757	S	S	*	*			cis	-172.6	153.1	-3.7	-150.8	82.3	0	0	0	100.3	R44	I42-R44 VanDerWaalsContact C-N 3.32Å; I42-R44 HydrophobicContact CG2-CB 3.91Å; I42-R44 HydrophobicContact CG2-CG 3.45Å; I42-R44 VanDerWaalsContact CG2-CG 3.45Å; I42-R44 PolarHBondContact O-N 3.17Å
43	W	48.3	Very low	49.9	Very low	258 Å²	258	142.1 Å²	142.1	98%	0.977	75%	0.752	S	S	*	*			trans	-58.6	94.8	169.8	-73.4	79	0	0	0	110.4
44	R	54.5	Low	49.9	Very low	214 Å²	214	140.4 Å²	140.4	81%	0.808	75%	0.746	S	S	*	*			trans	-153.4	96.3	172.8	-77.6	-63.3	-132.9	-85.3	-4.8	109.5	I42	I42-R44 VanDerWaalsContact C-N 3.32Å; I42-R44 HydrophobicContact CG2-CB 3.91Å; I42-R44 HydrophobicContact CG2-CG 3.45Å; I42-R44 VanDerWaalsContact CG2-CG 3.45Å; I42-R44 PolarHBondContact O-N 3.17Å
45	S	40.7	Very low	50.2	Low	105 Å²	105	137.4 Å²	137.4	73%	0.734	74%	0.736	S	S	*	*				-150.9	103.9	127.6	-167.1	0	0	0	0	108.9	E47	S45-E47 PolarHBondContact O-N 3Å
46	G	53.9	Low	50.4	Low	62 Å²	62	137.2 Å²	137.2	64%	0.639	72%	0.724	S	S	*	*			trans	-83.3	95.5	165.2	0	0	0	0	0	108.5
47	E	44.2	Very low	50.9	Low	174 Å²	174	137.9 Å²	137.9	81%	0.813	72%	0.72	S	S	*	*			trans	-101.2	124.7	158	-91.3	178.4	129.7	0	0	109.5	S45	S45-E47 PolarHBondContact O-N 3Å
48	K	53.3	Low	50.8	Low	184 Å²	184	142 Å²	142	80%	0.8	72%	0.721	S	S	*	*			trans	-94.4	116.2	-171.1	-32.2	-174.8	-165.7	-66.1	0	104.5	P50	K48-P50 VanDerWaalsContact O-CD 3.26Å; K48-P50 WeakPolarHBondContact O-CD 3.13Å
49	V	48.7	Very low	51	Low	114 Å²	114	139 Å²	139	69%	0.691	71%	0.71	S	S	*	*			trans	-91.5	103.1	167.4	-174.6	0	0	0	0	106.4
50	P	58.3	Low	51.2	Low	110 Å²	110	138.1 Å²	138.1	71%	0.714	71%	0.705	S	S	*	*			trans	-80.8	145.7	177.7	33.7	-29.6	0	0	0	109	K48	K48-P50 VanDerWaalsContact O-CD 3.26Å; K48-P50 WeakPolarHBondContact O-CD 3.13Å
51	F	50.2	Low	51.1	Low	164 Å²	164	139.4 Å²	139.4	72%	0.719	70%	0.697	S	S	*	*	S	Bend	trans	114.4	-13.9	151.8	-147.2	-100.4	0	0	0	119.6
52	V	48.8	Very low	51.7	Low	122 Å²	122	141.4 Å²	141.4	74%	0.739	70%	0.703	S	S	*	*	S	Bend	trans	-107	-16.2	173.1	-169.1	0	0	0	0	113.3	T54	V52-T54 PolarHBondContact O-N 2.9Å
53	Q	54.4	Low	52.3	Low	138 Å²	138	139.7 Å²	139.7	65%	0.645	70%	0.699	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.1	-14.3	-173.4	-77.1	175.2	16.8	0	0	115.3
54	T	53.8	Low	52.9	Low	106 Å²	106	129.9 Å²	129.9	65%	0.65	67%	0.669	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.9	-25	-176.4	37.6	0	0	0	0	113.9	V52	V52-T54 PolarHBondContact O-N 2.9Å
55	Y	51.7	Low	53.1	Low	174 Å²	174	127.4 Å²	127.4	68%	0.682	67%	0.667	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.4	-21	178.7	-55	-83.7	0	0	0	113
56	S	56.8	Low	54.1	Low	65 Å²	65	128.1 Å²	128.1	46%	0.455	67%	0.666	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.3	-25.7	-177.7	-178.3	0	0	0	0	114.2	F60	S56-F60 VanDerWaalsContact O-CD2 3.29Å; S56-F60 WeakPolarHBondContact O-CD2 3.36Å
57	L	55	Low	54.6	Low	140 Å²	140	130.7 Å²	130.7	73%	0.733	66%	0.662	S	S	*	*	S	Bend	trans	-77.3	-22.3	-174.4	-76.3	-176.7	0	0	0	114
58	R	53.5	Low	56.1	Low	200 Å²	200	125.3 Å²	125.3	76%	0.755	64%	0.641	S	S	*	*	S	Bend	trans	-84.9	-19.9	177.8	-160.9	-178.4	-75.3	-168.4	-3.3	113.3	F60 E61	R58-F60 PolarHBondContact O-N 3.26Å; R58-E61 WeakPolarHBondContact CG-OE2 3.36Å; R58-E61 PolarHBondContact O-N 2.88Å
59	A	49.8	Very low	57.5	Low	75 Å²	75	121.6 Å²	121.6	62%	0.62	63%	0.626	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71	-13.3	179	0	0	0	0	0	113.6
60	F	50.5	Low	59.2	Low	123 Å²	123	118 Å²	118	54%	0.539	61%	0.609	S	S	.	*	T	Hydrogen-bonded Turn	trans	-109.9	7.3	178.8	-63.2	-76.8	0	0	0	113.8	S56 R58 K62	S56-F60 VanDerWaalsContact O-CD2 3.29Å; S56-F60 WeakPolarHBondContact O-CD2 3.36Å; R58-F60 PolarHBondContact O-N 3.26Å; F60-K62 CarbonylContact O-C 3.45Å; F60-K62 PolarHBondContact O-N 2.91Å
61	E	54.7	Low	60.9	Low	154 Å²	154	118.3 Å²	118.3	72%	0.72	60%	0.604	S	S	*	*	S	Bend	trans	-64.5	-20.5	178.5	-127.2	175.8	-175.2	0	0	112.4	R58	R58-E61 WeakPolarHBondContact CG-OE2 3.36Å; R58-E61 PolarHBondContact O-N 2.88Å
62	K	61.4	Low	62.9	Low	176 Å²	176	118.8 Å²	118.8	77%	0.765	60%	0.6	S	S	*	*	S	Bend	trans	-109.3	109.5	157.5	-80.2	171.4	-179.9	174.2	0	107.4	F60 P64	F60-K62 CarbonylContact O-C 3.45Å; F60-K62 PolarHBondContact O-N 2.91Å; K62-P64 WeakPolarHBondContact O-CD 3.43Å; K62-P64 VanDerWaalsContact O-N 3.16Å
63	P	56.3	Low	65.1	Low	75 Å²	75	116.2 Å²	116.2	49%	0.487	58%	0.583	S	S	.	*			trans	-57.8	127	168.8	24.4	-30.8	0	0	0	106.3	Q65 T68	P63-Q65 PolarHBondContact O-N 3.36Å; P63-T68 HydrophobicContact CB-CG2 3.77Å; P63-T68 HydrophobicContact CG-CG2 3.97Å
64	P	59.9	Low	67.1	Low	53 Å²	53	116 Å²	116	34%	0.344	58%	0.58	S	S	.	*			trans	-54.1	115.4	175.8	18.8	-29	0	0	0	106.6	K62 V66 Q67 T68	K62-P64 WeakPolarHBondContact O-CD 3.43Å; K62-P64 VanDerWaalsContact O-N 3.16Å; P64-V66 PolarHBondContact O-N 3.08Å; P64-Q67 HydrophobicContact CB-CG 4.41Å; P64-Q67 HydrophobicContact CG-CB 4.11Å; P64-Q67 HydrophobicContact CG-CG 3.69Å; P64-Q67 WeakPolarHBondContact O-CA 3.28Å; P64-Q67 WeakPolarHBondContact O-CB 3.4Å; P64-Q67 PolarHBondContact O-N 3.26Å; P64-T68 PolarHBondContact O-N 3.3Å
65	Q	59.7	Low	69.1	Low	162 Å²	162	116.4 Å²	116.4	76%	0.757	57%	0.574	S	S	*	*	H	α-helix	trans	-54.4	-27.9	-168.5	-66.2	162.2	-8.2	0	0	111.7	P63 T68 Q69	P63-Q65 PolarHBondContact O-N 3.36Å; Q65-T68 WeakPolarHBondContact CA-OG1 3.43Å; Q65-T68 PolarHBondContact O-N 3.06Å; Q65-T68 PolarHBondContact O-OG1 2.94Å; Q65-Q69 PolarHBondContact O-N 3.07Å
66	V	60.3	Low	71.3	Confident	119 Å²	119	113.6 Å²	113.6	72%	0.721	57%	0.566	S	S	*	*	H	α-helix	trans	-60	-42	172	-177.1	0	0	0	0	112.8	P64 T68 Q69 A70	P64-V66 PolarHBondContact O-N 3.08Å; V66-T68 VanDerWaalsContact C-N 3.34Å; V66-Q69 PolarHBondContact O-N 3.33Å; V66-A70 WeakPolarHBondContact O-CB 3.4Å; V66-A70 PolarHBondContact O-N 2.72Å
67	Q	65.7	Low	73.3	Confident	117 Å²	117	115.6 Å²	115.6	55%	0.547	57%	0.568	S	S	.	*	H	α-helix	trans	-67.2	-36	175.3	-67.8	-177.3	24.4	0	0	111.3	P64 L71	P64-Q67 HydrophobicContact CB-CG 4.41Å; P64-Q67 HydrophobicContact CG-CB 4.11Å; P64-Q67 HydrophobicContact CG-CG 3.69Å; P64-Q67 WeakPolarHBondContact O-CA 3.28Å; P64-Q67 WeakPolarHBondContact O-CB 3.4Å; P64-Q67 PolarHBondContact O-N 3.26Å; Q67-L71 VanDerWaalsContact O-CG 3.26Å; Q67-L71 WeakPolarHBondContact O-CG 3.31Å; Q67-L71 PolarHBondContact O-N 3.05Å; Q67-L71 VanDerWaalsContact O-N 3.11Å
68	T	74.8	Confident	75.3	Confident	60 Å²	60	113.8 Å²	113.8	37%	0.368	56%	0.558	S	S	.	*	H	α-helix	trans	-68.5	-35.8	176	61.9	0	0	0	0	112.6	P63 P64 Q65 V66 R72	P63-T68 HydrophobicContact CB-CG2 3.77Å; P63-T68 HydrophobicContact CG-CG2 3.97Å; P64-T68 PolarHBondContact O-N 3.3Å; Q65-T68 WeakPolarHBondContact CA-OG1 3.43Å; Q65-T68 PolarHBondContact O-N 3.06Å; Q65-T68 PolarHBondContact O-OG1 2.94Å; V66-T68 VanDerWaalsContact C-N 3.34Å; T68-R72 WeakPolarHBondContact O-CG 3.48Å; T68-R72 PolarHBondContact O-N 3.41Å
69	Q	82.4	Confident	77.5	Confident	107 Å²	107	107.5 Å²	107.5	50%	0.5	54%	0.54	S	S	.	.	H	α-helix	trans	-69.7	-45.6	176.3	-173.9	58.3	45.6	0	0	111.4	Q65 V66 L71 R72 D73	Q65-Q69 PolarHBondContact O-N 3.07Å; V66-Q69 PolarHBondContact O-N 3.33Å; Q69-L71 VanDerWaalsContact C-N 3.3Å; Q69-L71 PolarHBondContact O-N 3.13Å; Q69-R72 WeakPolarHBondContact O-CB 3.44Å; Q69-R72 PolarHBondContact O-N 3.2Å; Q69-R72 VanDerWaalsContact O-N 3.08Å; Q69-D73 PolarHBondContact NE2-OD1 3.49Å; Q69-D73 PolarHBondContact O-N 2.78Å
70	A	86.1	Confident	79.8	Confident	39 Å²	39	106.4 Å²	106.4	32%	0.322	52%	0.523	S	S	.	.	H	α-helix	trans	-58.3	-42.2	177.5	0	0	0	0	0	112	V66 R72 D73 F74	V66-A70 WeakPolarHBondContact O-CB 3.4Å; V66-A70 PolarHBondContact O-N 2.72Å; A70-R72 VanDerWaalsContact C-N 3.34Å; A70-R72 PolarHBondContact O-N 2.83Å; A70-D73 PolarHBondContact O-N 3.41Å; A70-F74 HydrophobicContact CB-CE2 4.35Å; A70-F74 WeakPolarHBondContact O-CD2 3.41Å; A70-F74 WeakPolarHBondContact O-CG 3.36Å; A70-F74 PolarHBondContact O-N 3.12Å
71	L	93	Very high	82.1	Confident	116 Å²	116	104.8 Å²	104.8	61%	0.607	52%	0.52	S	S	*	.	H	α-helix	trans	-61.5	-40.8	175.7	-72.4	171.2	0	0	0	112.5	Q67 Q69 D73 F74 E75	Q67-L71 VanDerWaalsContact O-CG 3.26Å; Q67-L71 WeakPolarHBondContact O-CG 3.31Å; Q67-L71 PolarHBondContact O-N 3.05Å; Q67-L71 VanDerWaalsContact O-N 3.11Å; Q69-L71 VanDerWaalsContact C-N 3.3Å; Q69-L71 PolarHBondContact O-N 3.13Å; L71-D73 VanDerWaalsContact C-N 3.34Å; L71-F74 PolarHBondContact O-N 3.12Å; L71-E75 PolarHBondContact O-N 2.93Å
72	R	93.4	Very high	84.1	Confident	173 Å²	173	104.2 Å²	104.2	65%	0.653	52%	0.515	S	S	*	.	H	α-helix	trans	-65.6	-38.5	177.1	-69.4	-84.6	-74.6	-111	-5.3	111.7	T68 Q69 A70 E75 K76	T68-R72 WeakPolarHBondContact O-CG 3.48Å; T68-R72 PolarHBondContact O-N 3.41Å; Q69-R72 WeakPolarHBondContact O-CB 3.44Å; Q69-R72 PolarHBondContact O-N 3.2Å; Q69-R72 VanDerWaalsContact O-N 3.08Å; A70-R72 VanDerWaalsContact C-N 3.34Å; A70-R72 PolarHBondContact O-N 2.83Å; R72-E75 PolarHBondContact O-N 3.44Å; R72-K76 PolarHBondContact O-N 3.02Å
73	D	94.6	Very high	85.9	Confident	68 Å²	68	102.6 Å²	102.6	36%	0.364	51%	0.508	S	S	.	.	H	α-helix	trans	-68.1	-40.9	176.5	-63.2	-23.6	0	0	0	111.1	Q69 A70 L71 K76 H77	Q69-D73 PolarHBondContact NE2-OD1 3.49Å; Q69-D73 PolarHBondContact O-N 2.78Å; A70-D73 PolarHBondContact O-N 3.41Å; L71-D73 VanDerWaalsContact C-N 3.34Å; D73-K76 PolarHBondContact O-N 3.43Å; D73-H77 VanDerWaalsContact O-CG 3.31Å; D73-H77 PolarHBondContact O-N 3.38Å; D73-H77 PolarHBondContact O-ND1 3.36Å
74	F	96.1	Very high	87.9	Confident	133 Å²	133	104.8 Å²	104.8	58%	0.583	51%	0.511	S	S	*	.	H	α-helix	trans	-62	-43.6	173.2	-72.6	-56.2	0	0	0	112.5	A70 L71 K76 H77 L78	A70-F74 HydrophobicContact CB-CE2 4.35Å; A70-F74 WeakPolarHBondContact O-CD2 3.41Å; A70-F74 WeakPolarHBondContact O-CG 3.36Å; A70-F74 PolarHBondContact O-N 3.12Å; L71-F74 PolarHBondContact O-N 3.12Å; F74-K76 VanDerWaalsContact C-N 3.31Å; F74-K76 PolarHBondContact O-N 3.32Å; F74-H77 PolarHBondContact O-N 3.44Å; F74-L78 WeakPolarHBondContact O-CG 3.22Å; F74-L78 PolarHBondContact O-N 2.87Å
75	E	95.6	Very high	89.8	Confident	115 Å²	115	107 Å²	107	54%	0.537	52%	0.52	S	S	.	.	H	α-helix	trans	-60.8	-42.3	176.1	-176.9	176.1	-167.8	0	0	111.6	L71 R72 L78 N79	L71-E75 PolarHBondContact O-N 2.93Å; R72-E75 PolarHBondContact O-N 3.44Å; E75-L78 PolarHBondContact O-N 3.32Å; E75-N79 PolarHBondContact O-N 3.06Å; E75-N79 PolarHBondContact O-ND2 2.83Å
76	K	97.4	Very high	91.6	Very high	116 Å²	116	105.3 Å²	105.3	50%	0.504	51%	0.511	S	S	.	.	H	α-helix	trans	-60.2	-50.5	174	-176.2	-175.1	175	-63.2	0	111.3	R72 D73 F74 L78 N79 D80	R72-K76 PolarHBondContact O-N 3.02Å; D73-K76 PolarHBondContact O-N 3.43Å; F74-K76 VanDerWaalsContact C-N 3.31Å; F74-K76 PolarHBondContact O-N 3.32Å; K76-L78 VanDerWaalsContact C-N 3.29Å; K76-L78 PolarHBondContact O-N 3.08Å; K76-N79 PolarHBondContact O-N 2.99Å; K76-N79 VanDerWaalsContact O-N 3.1Å; K76-D80 IonicContact NZ-OD2 2.73Å; K76-D80 PolarHBondContact NZ-OD2 3.5Å; K76-D80 PolarHBondContact O-N 2.93Å
77	H	98.3	Very high	93.4	Very high	106 Å²	106	103.1 Å²	103.1	49%	0.491	50%	0.501	S	S	.	.	H	α-helix	trans	-59.1	-40.4	178.8	-68.6	129.4	0	0	0	112.3	D73 F74 N79 D80 L81	D73-H77 VanDerWaalsContact O-CG 3.31Å; D73-H77 PolarHBondContact O-N 3.38Å; D73-H77 PolarHBondContact O-ND1 3.36Å; F74-H77 PolarHBondContact O-N 3.44Å; H77-N79 VanDerWaalsContact C-N 3.34Å; H77-N79 PolarHBondContact O-N 3.32Å; H77-D80 PolarHBondContact O-N 3.45Å; H77-L81 WeakPolarHBondContact O-CB 3.38Å; H77-L81 WeakPolarHBondContact O-CG 3.37Å; H77-L81 PolarHBondContact O-N 3.09Å
78	L	98.3	Very high	95	Very high	102 Å²	102	102.2 Å²	102.2	53%	0.534	50%	0.499	S	S	.	.	H	α-helix	trans	-62.9	-40.8	175.2	-75	174.8	0	0	0	112.2	F74 E75 K76 K82	F74-L78 WeakPolarHBondContact O-CG 3.22Å; F74-L78 PolarHBondContact O-N 2.87Å; E75-L78 PolarHBondContact O-N 3.32Å; K76-L78 VanDerWaalsContact C-N 3.29Å; K76-L78 PolarHBondContact O-N 3.08Å; L78-K82 WeakPolarHBondContact O-CB 3.3Å; L78-K82 VanDerWaalsContact O-CG 3.3Å; L78-K82 WeakPolarHBondContact O-CG 3.49Å; L78-K82 PolarHBondContact O-N 3Å
79	N	98.3	Very high	96.1	Very high	69 Å²	69	106.2 Å²	106.2	37%	0.369	51%	0.512	S	S	.	.	H	α-helix	trans	-67.6	-40.1	177.7	-75.5	-40.3	0	0	0	112.1	E75 K76 H77 K82 K83	E75-N79 PolarHBondContact O-N 3.06Å; E75-N79 PolarHBondContact O-ND2 2.83Å; K76-N79 PolarHBondContact O-N 2.99Å; K76-N79 VanDerWaalsContact O-N 3.1Å; H77-N79 VanDerWaalsContact C-N 3.34Å; H77-N79 PolarHBondContact O-N 3.32Å; N79-K82 PolarHBondContact O-N 3.46Å; N79-K83 WeakPolarHBondContact O-CG 3.25Å; N79-K83 PolarHBondContact O-N 3.13Å; N79-K83 VanDerWaalsContact O-N 3.08Å
80	D	98.3	Very high	96.9	Very high	51 Å²	51	104.6 Å²	104.6	27%	0.273	51%	0.506	S	S	.	.	H	α-helix	trans	-64.1	-46.5	176.2	-67.8	-21.5	0	0	0	110.5	K76 H77 K82 K83 E84	K76-D80 IonicContact NZ-OD2 2.73Å; K76-D80 PolarHBondContact NZ-OD2 3.5Å; K76-D80 PolarHBondContact O-N 2.93Å; H77-D80 PolarHBondContact O-N 3.45Å; D80-K82 VanDerWaalsContact C-N 3.33Å; D80-K82 PolarHBondContact O-N 2.86Å; D80-K83 WeakPolarHBondContact O-CB 3.32Å; D80-K83 PolarHBondContact O-N 3.04Å; D80-K83 VanDerWaalsContact O-N 3.09Å; D80-E84 PolarHBondContact O-N 3.37Å
81	L	98.8	Very high	97.5	Very high	89 Å²	89	111.2 Å²	111.2	47%	0.466	52%	0.523	S	S	.	.	H	α-helix	trans	-59.8	-38.8	174.1	-80.5	166.9	0	0	0	113.2	H77 K83 E84 N85	H77-L81 WeakPolarHBondContact O-CB 3.38Å; H77-L81 WeakPolarHBondContact O-CG 3.37Å; H77-L81 PolarHBondContact O-N 3.09Å; L81-K83 VanDerWaalsContact C-N 3.33Å; L81-E84 PolarHBondContact O-N 2.82Å; L81-N85 WeakPolarHBondContact O-CB 3.44Å; L81-N85 PolarHBondContact O-N 3.48Å; L81-N85 PolarHBondContact O-ND2 3.3Å
82	K	98.5	Very high	97.7	Very high	142 Å²	142	109.8 Å²	109.8	62%	0.617	52%	0.515	S	S	*	.	H	α-helix	trans	-63	-40.5	174.9	-79.3	174.1	179.5	176.5	0	111.6	L78 N79 D80 F86	L78-K82 WeakPolarHBondContact O-CB 3.3Å; L78-K82 VanDerWaalsContact O-CG 3.3Å; L78-K82 WeakPolarHBondContact O-CG 3.49Å; L78-K82 PolarHBondContact O-N 3Å; N79-K82 PolarHBondContact O-N 3.46Å; D80-K82 VanDerWaalsContact C-N 3.33Å; D80-K82 PolarHBondContact O-N 2.86Å; K82-F86 WeakPolarHBondContact O-CB 3.37Å; K82-F86 PolarHBondContact O-N 3.12Å
83	K	98.5	Very high	97.9	Very high	142 Å²	142	107.6 Å²	107.6	62%	0.617	51%	0.507	S	S	*	.	H	α-helix	trans	-66.4	-45.6	177.1	-70.5	170.8	-175.4	170	0	111.5	N79 D80 L81 F86 S87	N79-K83 WeakPolarHBondContact O-CG 3.25Å; N79-K83 PolarHBondContact O-N 3.13Å; N79-K83 VanDerWaalsContact O-N 3.08Å; D80-K83 WeakPolarHBondContact O-CB 3.32Å; D80-K83 PolarHBondContact O-N 3.04Å; D80-K83 VanDerWaalsContact O-N 3.09Å; L81-K83 VanDerWaalsContact C-N 3.33Å; K83-F86 PolarHBondContact O-N 3.09Å; K83-S87 WeakPolarHBondContact O-CB 3.49Å; K83-S87 PolarHBondContact O-N 2.88Å
84	E	98.5	Very high	98.1	Very high	121 Å²	121	109.6 Å²	109.6	57%	0.565	51%	0.513	S	S	*	.	H	α-helix	trans	-60.5	-46.7	176	-71.6	-177.9	172.2	0	0	111.1	D80 L81 F86 S87 L88	D80-E84 PolarHBondContact O-N 3.37Å; L81-E84 PolarHBondContact O-N 2.82Å; E84-F86 VanDerWaalsContact C-N 3.31Å; E84-F86 PolarHBondContact O-N 2.76Å; E84-S87 WeakPolarHBondContact O-CB 3.5Å; E84-S87 PolarHBondContact O-N 3.35Å; E84-S87 VanDerWaalsContact O-N 3.15Å; E84-L88 WeakPolarHBondContact O-CB 3.22Å; E84-L88 VanDerWaalsContact O-CG 3.29Å; E84-L88 WeakPolarHBondContact O-CG 3.42Å; E84-L88 PolarHBondContact O-N 3.35Å
85	N	98.4	Very high	98.1	Very high	99 Å²	99	107.9 Å²	107.9	53%	0.529	51%	0.509	S	S	.	.	H	α-helix	trans	-59.3	-39.6	175.8	-85.3	-62.2	0	0	0	112.9	L81 K89	L81-N85 WeakPolarHBondContact O-CB 3.44Å; L81-N85 PolarHBondContact O-N 3.48Å; L81-N85 PolarHBondContact O-ND2 3.3Å; N85-K89 WeakPolarHBondContact O-CB 3.17Å; N85-K89 PolarHBondContact O-N 3.48Å
86	F	98.8	Very high	98.1	Very high	127 Å²	127	108.1 Å²	108.1	56%	0.557	51%	0.511	S	S	*	.	H	α-helix	trans	-65.1	-45.5	174.7	179.1	-102.2	0	0	0	111.7	K82 K83 E84 L88 K89 L90	K82-F86 WeakPolarHBondContact O-CB 3.37Å; K82-F86 PolarHBondContact O-N 3.12Å; K83-F86 PolarHBondContact O-N 3.09Å; E84-F86 VanDerWaalsContact C-N 3.31Å; E84-F86 PolarHBondContact O-N 2.76Å; F86-L88 PolarHBondContact O-N 2.91Å; F86-K89 PolarHBondContact O-N 3.15Å; F86-L90 HydrophobicContact CD1-CD1 4.18Å; F86-L90 HydrophobicContact CE1-CD1 3.54Å; F86-L90 HydrophobicContact CE1-CG 4.23Å; F86-L90 HydrophobicContact CZ-CD1 3.82Å; F86-L90 HydrophobicContact CZ-CD2 4.38Å; F86-L90 HydrophobicContact CZ-CG 4.2Å; F86-L90 PolarHBondContact O-N 3.34Å; F86-L90 VanDerWaalsContact O-N 3.12Å
87	S	98.6	Very high	97.9	Very high	74 Å²	74	106.4 Å²	106.4	52%	0.517	50%	0.504	S	S	.	.	H	α-helix	trans	-60.3	-45.2	176.9	-175.8	0	0	0	0	112	K83 E84 K89 L90 R91	K83-S87 WeakPolarHBondContact O-CB 3.49Å; K83-S87 PolarHBondContact O-N 2.88Å; E84-S87 WeakPolarHBondContact O-CB 3.5Å; E84-S87 PolarHBondContact O-N 3.35Å; E84-S87 VanDerWaalsContact O-N 3.15Å; S87-K89 PolarHBondContact O-N 2.9Å; S87-L90 PolarHBondContact O-N 3.26Å; S87-R91 PolarHBondContact O-N 2.93Å
88	L	98.7	Very high	97.7	Very high	97 Å²	97	109 Å²	109	51%	0.508	51%	0.51	S	S	.	.	H	α-helix	trans	-61.8	-44.6	177.2	-72	172.7	0	0	0	111.4	E84 F86 L90 R91 I92	E84-L88 WeakPolarHBondContact O-CB 3.22Å; E84-L88 VanDerWaalsContact O-CG 3.29Å; E84-L88 WeakPolarHBondContact O-CG 3.42Å; E84-L88 PolarHBondContact O-N 3.35Å; F86-L88 PolarHBondContact O-N 2.91Å; L88-L90 VanDerWaalsContact C-N 3.32Å; L88-L90 PolarHBondContact O-N 3Å; L88-R91 PolarHBondContact O-N 3.4Å; L88-R91 VanDerWaalsContact O-N 3.13Å; L88-I92 WeakPolarHBondContact O-CB 3.3Å; L88-I92 VanDerWaalsContact O-CG1 3.3Å; L88-I92 WeakPolarHBondContact O-CG1 3.43Å; L88-I92 PolarHBondContact O-N 2.91Å
89	K	98.5	Very high	97.4	Very high	145 Å²	145	109.8 Å²	109.8	63%	0.63	51%	0.512	S	S	*	.	H	α-helix	trans	-56	-45.7	176.2	-175.4	-177.8	-62.1	-173.2	0	111.9	N85 F86 S87 I92 Y93	N85-K89 WeakPolarHBondContact O-CB 3.17Å; N85-K89 PolarHBondContact O-N 3.48Å; F86-K89 PolarHBondContact O-N 3.15Å; S87-K89 PolarHBondContact O-N 2.9Å; K89-I92 PolarHBondContact O-N 3.28Å; K89-Y93 VanDerWaalsContact O-CB 3.3Å; K89-Y93 WeakPolarHBondContact O-CB 3.38Å; K89-Y93 PolarHBondContact O-N 3.1Å
90	L	98.6	Very high	96.9	Very high	72 Å²	72	111.4 Å²	111.4	38%	0.377	52%	0.517	S	S	.	.	H	α-helix	trans	-62.9	-43.3	177	-68.9	-179.9	0	0	0	111.8	F86 S87 L88 Y93 F94	F86-L90 HydrophobicContact CD1-CD1 4.18Å; F86-L90 HydrophobicContact CE1-CD1 3.54Å; F86-L90 HydrophobicContact CE1-CG 4.23Å; F86-L90 HydrophobicContact CZ-CD1 3.82Å; F86-L90 HydrophobicContact CZ-CD2 4.38Å; F86-L90 HydrophobicContact CZ-CG 4.2Å; F86-L90 PolarHBondContact O-N 3.34Å; F86-L90 VanDerWaalsContact O-N 3.12Å; S87-L90 PolarHBondContact O-N 3.26Å; L88-L90 VanDerWaalsContact C-N 3.32Å; L88-L90 PolarHBondContact O-N 3Å; L90-Y93 PolarHBondContact O-N 3.36Å; L90-F94 HydrophobicContact CB-CE2 4.42Å; L90-F94 WeakPolarHBondContact O-CD2 3.29Å; L90-F94 PolarHBondContact O-N 3.38Å; L90-F94 VanDerWaalsContact O-N 3.09Å
91	R	98.1	Very high	96.2	Very high	179 Å²	179	114.5 Å²	114.5	68%	0.675	53%	0.53	S	S	*	.	H	α-helix	trans	-64.1	-43.3	179.6	-173	167.7	-179.8	169.8	-1.5	111.9	S87 L88 L95	S87-R91 PolarHBondContact O-N 2.93Å; L88-R91 PolarHBondContact O-N 3.4Å; L88-R91 VanDerWaalsContact O-N 3.13Å; R91-L95 HydrophobicContact CG-CD1 3.98Å; R91-L95 WeakPolarHBondContact O-CB 3.43Å; R91-L95 WeakPolarHBondContact O-CD1 3.49Å; R91-L95 WeakPolarHBondContact O-CG 3.39Å; R91-L95 PolarHBondContact O-N 3.44Å; R91-L95 VanDerWaalsContact O-N 3.09Å
92	I	98.1	Very high	95.5	Very high	86 Å²	86	116.6 Å²	116.6	44%	0.441	54%	0.536	S	S	.	.	H	α-helix	trans	-62	-51.3	176.3	-68.5	166.3	0	0	0	109.8	L88 K89 F94 L95 E96	L88-I92 WeakPolarHBondContact O-CB 3.3Å; L88-I92 VanDerWaalsContact O-CG1 3.3Å; L88-I92 WeakPolarHBondContact O-CG1 3.43Å; L88-I92 PolarHBondContact O-N 2.91Å; K89-I92 PolarHBondContact O-N 3.28Å; I92-F94 PolarHBondContact O-N 2.96Å; I92-L95 WeakPolarHBondContact O-CB 3.08Å; I92-L95 PolarHBondContact O-N 2.93Å; I92-E96 VanDerWaalsContact CG2-CD 3.48Å; I92-E96 HydrophobicContact CG2-CG 4.11Å; I92-E96 WeakPolarHBondContact CG2-OE1 3.35Å; I92-E96 WeakPolarHBondContact O-CB 3.46Å; I92-E96 WeakPolarHBondContact O-CG 3.48Å; I92-E96 PolarHBondContact O-N 3.48Å
93	Y	97.7	Very high	94.5	Very high	127 Å²	127	115.8 Å²	115.8	50%	0.498	53%	0.53	S	S	.	.	H	α-helix	trans	-52.7	-50.7	179.8	175.3	-92.9	0	0	0	112.8	K89 L90 L95 E96 E97	K89-Y93 VanDerWaalsContact O-CB 3.3Å; K89-Y93 WeakPolarHBondContact O-CB 3.38Å; K89-Y93 PolarHBondContact O-N 3.1Å; L90-Y93 PolarHBondContact O-N 3.36Å; Y93-L95 VanDerWaalsContact C-N 3.34Å; Y93-L95 PolarHBondContact O-N 2.95Å; Y93-E96 PolarHBondContact O-N 3.09Å; Y93-E97 WeakPolarHBondContact O-CB 3.33Å; Y93-E97 PolarHBondContact O-N 3.33Å
94	F	97.4	Very high	93.4	Very high	110 Å²	110	112.4 Å²	112.4	48%	0.482	52%	0.516	S	S	.	.	H	α-helix	trans	-70	-30.6	179.8	-67.9	-53.6	0	0	0	113.2	L90 I92 R98	L90-F94 HydrophobicContact CB-CE2 4.42Å; L90-F94 WeakPolarHBondContact O-CD2 3.29Å; L90-F94 PolarHBondContact O-N 3.38Å; L90-F94 VanDerWaalsContact O-N 3.09Å; I92-F94 PolarHBondContact O-N 2.96Å; F94-R98 WeakPolarHBondContact O-CB 3.48Å; F94-R98 VanDerWaalsContact O-CG 3.22Å; F94-R98 WeakPolarHBondContact O-CG 3.46Å; F94-R98 PolarHBondContact O-N 2.93Å; F94-R98 VanDerWaalsContact O-N 3.08Å
95	L	96.8	Very high	92	Very high	97 Å²	97	109.2 Å²	109.2	51%	0.508	51%	0.51	S	S	.	.	H	α-helix	trans	-68.3	-45	174.2	-75.8	170.9	0	0	0	110.9	R91 I92 Y93 R98 M99	R91-L95 HydrophobicContact CG-CD1 3.98Å; R91-L95 WeakPolarHBondContact O-CB 3.43Å; R91-L95 WeakPolarHBondContact O-CD1 3.49Å; R91-L95 WeakPolarHBondContact O-CG 3.39Å; R91-L95 PolarHBondContact O-N 3.44Å; R91-L95 VanDerWaalsContact O-N 3.09Å; I92-L95 WeakPolarHBondContact O-CB 3.08Å; I92-L95 PolarHBondContact O-N 2.93Å; Y93-L95 VanDerWaalsContact C-N 3.34Å; Y93-L95 PolarHBondContact O-N 2.95Å; L95-R98 PolarHBondContact O-N 2.94Å; L95-M99 WeakPolarHBondContact O-CB 3.48Å; L95-M99 WeakPolarHBondContact O-CG 3.43Å; L95-M99 PolarHBondContact O-N 3.44Å
96	E	95.1	Very high	90.6	Very high	120 Å²	120	107.8 Å²	107.8	56%	0.561	51%	0.508	S	S	*	.	H	α-helix	trans	-59.9	-47.6	175.8	-72.3	172.8	167.6	0	0	111	I92 Y93 R98 M99 Q100	I92-E96 VanDerWaalsContact CG2-CD 3.48Å; I92-E96 HydrophobicContact CG2-CG 4.11Å; I92-E96 WeakPolarHBondContact CG2-OE1 3.35Å; I92-E96 WeakPolarHBondContact O-CB 3.46Å; I92-E96 WeakPolarHBondContact O-CG 3.48Å; I92-E96 PolarHBondContact O-N 3.48Å; Y93-E96 PolarHBondContact O-N 3.09Å; E96-R98 PolarHBondContact O-N 3.08Å; E96-M99 PolarHBondContact O-N 2.73Å; E96-Q100 WeakPolarHBondContact O-CB 2.98Å; E96-Q100 PolarHBondContact O-N 3.11Å
97	E	93.9	Very high	88.9	Confident	80 Å²	80	106.3 Å²	106.3	37%	0.374	50%	0.499	S	S	.	.	H	α-helix	trans	-58.1	-46.3	176.8	-178.1	173.7	-134.1	0	0	111.8	Y93 M99 Q100 Q101	Y93-E97 WeakPolarHBondContact O-CB 3.33Å; Y93-E97 PolarHBondContact O-N 3.33Å; E97-M99 PolarHBondContact O-N 2.97Å; E97-Q100 PolarHBondContact O-N 3.22Å; E97-Q101 VanDerWaalsContact O-CG 3.25Å; E97-Q101 WeakPolarHBondContact O-CG 3.3Å; E97-Q101 PolarHBondContact O-N 3.01Å
98	R	93.8	Very high	87.3	Confident	161 Å²	161	107.4 Å²	107.4	61%	0.608	50%	0.496	S	S	*	.	H	α-helix	trans	-68.9	-32.4	178.1	-72.4	-179.8	68	162.4	4	113.2	F94 L95 E96 K102	F94-R98 WeakPolarHBondContact O-CB 3.48Å; F94-R98 VanDerWaalsContact O-CG 3.22Å; F94-R98 WeakPolarHBondContact O-CG 3.46Å; F94-R98 PolarHBondContact O-N 2.93Å; F94-R98 VanDerWaalsContact O-N 3.08Å; L95-R98 PolarHBondContact O-N 2.94Å; E96-R98 PolarHBondContact O-N 3.08Å; R98-K102 WeakPolarHBondContact O-CG 3.26Å; R98-K102 PolarHBondContact O-N 3.4Å
99	M	91.7	Very high	85.6	Confident	117 Å²	117	108.4 Å²	108.4	58%	0.576	50%	0.502	S	S	*	.	H	α-helix	trans	-71.5	-42.5	175.2	-78.9	-55.4	-40.5	0	0	111.3	L95 E96 E97 K102 Y103	L95-M99 WeakPolarHBondContact O-CB 3.48Å; L95-M99 WeakPolarHBondContact O-CG 3.43Å; L95-M99 PolarHBondContact O-N 3.44Å; E96-M99 PolarHBondContact O-N 2.73Å; E97-M99 PolarHBondContact O-N 2.97Å; M99-K102 PolarHBondContact O-N 3.06Å; M99-Y103 PolarHBondContact O-N 3.37Å
100	Q	89.1	Confident	84	Confident	103 Å²	103	107 Å²	107	48%	0.481	50%	0.5	S	S	.	.	H	α-helix	trans	-62.4	-46.8	177.7	-166.9	66.5	28.7	0	0	111.2	E96 E97 K102 Y103 E104	E96-Q100 WeakPolarHBondContact O-CB 2.98Å; E96-Q100 PolarHBondContact O-N 3.11Å; E97-Q100 PolarHBondContact O-N 3.22Å; Q100-K102 VanDerWaalsContact C-N 3.26Å; Q100-K102 PolarHBondContact O-N 3.45Å; Q100-Y103 PolarHBondContact O-N 3.08Å; Q100-E104 HydrophobicContact CG-CG 4.39Å; Q100-E104 PolarHBondContact NE2-OE1 2.96Å; Q100-E104 WeakPolarHBondContact O-CG 3.38Å; Q100-E104 PolarHBondContact O-N 3.38Å
101	Q	82.4	Confident	82.2	Confident	117 Å²	117	111.9 Å²	111.9	55%	0.547	51%	0.514	S	S	.	.	H	α-helix	trans	-55.8	-40.7	177.4	-74.4	170.6	4.7	0	0	112.7	E97 A105	E97-Q101 VanDerWaalsContact O-CG 3.25Å; E97-Q101 WeakPolarHBondContact O-CG 3.3Å; E97-Q101 PolarHBondContact O-N 3.01Å; Q101-A105 VanDerWaalsContact O-CB 3.31Å; Q101-A105 WeakPolarHBondContact O-CB 3.41Å; Q101-A105 PolarHBondContact O-N 3.32Å; Q101-A105 VanDerWaalsContact O-N 3.12Å
102	K	83.4	Confident	80.4	Confident	133 Å²	133	112 Å²	112	58%	0.578	52%	0.52	S	S	*	.	H	α-helix	trans	-69.9	-36.3	177.2	-72.1	177.8	177.7	-172.8	0	112.6	R98 M99 Q100 S106	R98-K102 WeakPolarHBondContact O-CG 3.26Å; R98-K102 PolarHBondContact O-N 3.4Å; M99-K102 PolarHBondContact O-N 3.06Å; Q100-K102 VanDerWaalsContact C-N 3.26Å; Q100-K102 PolarHBondContact O-N 3.45Å; K102-S106 WeakPolarHBondContact O-CB 3.48Å; K102-S106 PolarHBondContact O-N 2.99Å; K102-S106 VanDerWaalsContact O-N 3.13Å
103	Y	77.8	Confident	78.5	Confident	125 Å²	125	118.8 Å²	118.8	49%	0.49	54%	0.54	S	S	.	.	H	α-helix	trans	-69.9	-44.6	179.5	-175.8	-103.3	0	0	0	111.9	M99 Q100 S106 R107	M99-Y103 PolarHBondContact O-N 3.37Å; Q100-Y103 PolarHBondContact O-N 3.08Å; Y103-S106 PolarHBondContact O-N 2.99Å; Y103-R107 HydrophobicContact CE1-CG 4.3Å; Y103-R107 WeakPolarHBondContact O-CG 3.43Å; Y103-R107 PolarHBondContact O-N 2.96Å; Y103-R107 VanDerWaalsContact O-N 3.12Å; Y103-R107 PolarHBondContact OH-NH1 2.9Å
104	E	75.3	Confident	76.1	Confident	71 Å²	71	119.1 Å²	119.1	33%	0.332	58%	0.582	S	S	.	*	H	α-helix	trans	-62.3	-52.3	174.8	-62	-55	160.2	0	0	110.5	Q100 S106 R107 E108	Q100-E104 HydrophobicContact CG-CG 4.39Å; Q100-E104 PolarHBondContact NE2-OE1 2.96Å; Q100-E104 WeakPolarHBondContact O-CG 3.38Å; Q100-E104 PolarHBondContact O-N 3.38Å; E104-S106 PolarHBondContact O-N 3.28Å; E104-S106 VanDerWaalsContact O-N 3.07Å; E104-R107 WeakPolarHBondContact O-CA 3.26Å; E104-R107 WeakPolarHBondContact O-CB 3.48Å; E104-R107 PolarHBondContact O-N 2.95Å; E104-E108 WeakPolarHBondContact CB-OE2 3.48Å; E104-E108 PolarHBondContact O-N 2.94Å
105	A	68.8	Low	75	Confident	54 Å²	54	119.6 Å²	119.6	45%	0.446	59%	0.587	S	S	.	*	H	α-helix	trans	-52.9	-40.1	178.1	0	0	0	0	0	113.1	Q101 D109	Q101-A105 VanDerWaalsContact O-CB 3.31Å; Q101-A105 WeakPolarHBondContact O-CB 3.41Å; Q101-A105 PolarHBondContact O-N 3.32Å; Q101-A105 VanDerWaalsContact O-N 3.12Å; A105-D109 PolarHBondContact O-N 2.67Å
106	S	69.1	Low	73.8	Confident	69 Å²	69	120.7 Å²	120.7	48%	0.483	59%	0.591	S	S	.	*	H	α-helix	trans	-69.2	-28.6	175.6	-174.6	0	0	0	0	113.8	K102 Y103 E104 I110	K102-S106 WeakPolarHBondContact O-CB 3.48Å; K102-S106 PolarHBondContact O-N 2.99Å; K102-S106 VanDerWaalsContact O-N 3.13Å; Y103-S106 PolarHBondContact O-N 2.99Å; E104-S106 PolarHBondContact O-N 3.28Å; E104-S106 VanDerWaalsContact O-N 3.07Å; S106-I110 WeakPolarHBondContact O-CD1 3.44Å; S106-I110 WeakPolarHBondContact O-CG1 3.17Å
107	R	64.6	Low	72.7	Confident	95 Å²	95	120.8 Å²	120.8	36%	0.358	59%	0.592	S	S	.	*	H	α-helix	trans	-78.8	-45.8	176.8	-76.1	174.1	67.1	117.8	1	111.3	Y103 E104 D109 I110 Y111	Y103-R107 HydrophobicContact CE1-CG 4.3Å; Y103-R107 WeakPolarHBondContact O-CG 3.43Å; Y103-R107 PolarHBondContact O-N 2.96Å; Y103-R107 VanDerWaalsContact O-N 3.12Å; Y103-R107 PolarHBondContact OH-NH1 2.9Å; E104-R107 WeakPolarHBondContact O-CA 3.26Å; E104-R107 WeakPolarHBondContact O-CB 3.48Å; E104-R107 PolarHBondContact O-N 2.95Å; R107-D109 VanDerWaalsContact C-N 3.25Å; R107-D109 PolarHBondContact O-N 3.41Å; R107-I110 PolarHBondContact O-N 2.75Å; R107-I110 VanDerWaalsContact O-N 3.08Å; R107-Y111 WeakPolarHBondContact O-CD2 3.46Å; R107-Y111 PolarHBondContact O-N 2.98Å
108	E	65.1	Low	71.4	Confident	97 Å²	97	123.2 Å²	123.2	45%	0.453	61%	0.605	S	S	.	*	H	α-helix	trans	-55	-41.3	177	-92	74.1	-119.2	0	0	112.3	E104 I110 Y111 K112	E104-E108 WeakPolarHBondContact CB-OE2 3.48Å; E104-E108 PolarHBondContact O-N 2.94Å; E108-I110 VanDerWaalsContact C-N 3.29Å; E108-I110 PolarHBondContact O-N 3.44Å; E108-Y111 PolarHBondContact O-N 3.38Å; E108-K112 VanDerWaalsContact O-CG 3.28Å; E108-K112 WeakPolarHBondContact O-CG 3.29Å; E108-K112 PolarHBondContact O-N 3.26Å; E108-K112 VanDerWaalsContact O-N 3.12Å
109	D	63.1	Low	70	Confident	119 Å²	119	120.8 Å²	120.8	64%	0.636	61%	0.605	S	S	*	*	H	α-helix	trans	-64.9	-30.2	178.6	-82.5	-7.5	0	0	0	113.6	A105 R107	A105-D109 PolarHBondContact O-N 2.67Å; R107-D109 VanDerWaalsContact C-N 3.25Å; R107-D109 PolarHBondContact O-N 3.41Å
110	I	64.3	Low	68.6	Low	116 Å²	116	121.1 Å²	121.1	60%	0.595	61%	0.607	S	S	*	*	H	α-helix	trans	-73	-42.3	177.3	-65.8	167.3	0	0	0	110.3	S106 R107 E108 K112 R113	S106-I110 WeakPolarHBondContact O-CD1 3.44Å; S106-I110 WeakPolarHBondContact O-CG1 3.17Å; R107-I110 PolarHBondContact O-N 2.75Å; R107-I110 VanDerWaalsContact O-N 3.08Å; E108-I110 VanDerWaalsContact C-N 3.29Å; E108-I110 PolarHBondContact O-N 3.44Å; I110-K112 VanDerWaalsContact C-N 3.34Å; I110-K112 PolarHBondContact O-N 3.18Å; I110-R113 PolarHBondContact O-N 3.22Å
111	Y	59.6	Low	67.1	Low	173 Å²	173	122.4 Å²	122.4	68%	0.678	62%	0.616	S	S	*	*	H	α-helix	trans	-74.1	-22	-179.8	-70.2	-73.1	0	0	0	113.8	R107 E108	R107-Y111 WeakPolarHBondContact O-CD2 3.46Å; R107-Y111 PolarHBondContact O-N 2.98Å; E108-Y111 PolarHBondContact O-N 3.38Å
112	K	60.9	Low	65.9	Low	183 Å²	183	122.8 Å²	122.8	80%	0.796	62%	0.621	S	S	*	*	T	Hydrogen-bonded Turn	trans	-82.1	-13	175.7	-68.4	-71.6	-177.3	-176.9	0	113.9	E108 I110	E108-K112 VanDerWaalsContact O-CG 3.28Å; E108-K112 WeakPolarHBondContact O-CG 3.29Å; E108-K112 PolarHBondContact O-N 3.26Å; E108-K112 VanDerWaalsContact O-N 3.12Å; I110-K112 VanDerWaalsContact C-N 3.34Å; I110-K112 PolarHBondContact O-N 3.18Å
113	R	59.4	Low	64.5	Low	228 Å²	228	121.9 Å²	121.9	86%	0.86	63%	0.625	S	S	*	*			trans	-96.3	-10.5	-179.8	-170.2	178.1	-70.2	-114.5	1.5	113.3	I110	I110-R113 PolarHBondContact O-N 3.22Å
114	G	45.5	Very low	63.2	Low	133 Å²	133	121.6 Å²	121.6	100%	1.371	64%	0.637	S	S	*	*			trans	-89.5	0	177.3	0	0	0	0	0	113.7

Retrieved 114 of 114 residues in 115.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).