A0A087WX31_HUMAN Loading...

Neurotrophic receptor tyrosine kinase 3

AlphaFold DB , UniProt , Accession A0A087WX31, Species HUMAN (Homo sapiens, Human), Gene NTRK3, Length 49 aa.

						>A0A087WX31_HUMAN|A0A087WX31|NTRK3
THKPEEDTFGVPWLSSVVRRTQPAHCTTSTTASPRPRHWMPGPTLWSLA
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	T	40.3	Very low	52.2	Low	200 Å²	200	144.4 Å²	144.4	100%	1.227	77%	0.768	S	S	*	*				0	123.2	0	-37.1	0	0	0	0	107.8
2	H	45.9	Very low	52.4	Low	176 Å²	176	140.2 Å²	140.2	82%	0.815	76%	0.755	S	S	*	*			trans	-56.2	143.8	-168.5	-124.6	-104.5	0	0	0	114.7
3	K	47.2	Very low	52.2	Low	199 Å²	199	143.7 Å²	143.7	87%	0.865	75%	0.751	S	S	*	*				-177.5	152.9	127.5	-108.4	-175.7	176.7	-177.1	0	113.2
4	P	51.8	Low	52.3	Low	81 Å²	81	141.1 Å²	141.1	53%	0.526	74%	0.738	S	S	.	*				-122.4	146.2	-89.2	34.4	-19.7	0	0	0	112.5
5	E	54.7	Low	52.4	Low	193 Å²	193	137.1 Å²	137.1	90%	0.902	73%	0.726	S	S	*	*			trans	-82.8	102.4	155.6	-165.5	176.4	118.3	0	0	106.3
6	E	56.6	Low	52.4	Low	171 Å²	171	132.4 Å²	132.4	80%	0.799	71%	0.708	S	S	*	*			trans	-133.2	93.5	160.7	-75.7	-168.6	113.8	0	0	104.5
7	D	52.6	Low	52.5	Low	123 Å²	123	128.9 Å²	128.9	66%	0.658	69%	0.693	S	S	*	*				63.8	91.1	79.3	-143.3	-60.7	0	0	0	110.8
8	T	60.8	Low	52.7	Low	96 Å²	96	128.1 Å²	128.1	59%	0.589	69%	0.692	S	S	*	*			trans	67.3	155.7	133.5	-40.2	0	0	0	0	118.9
9	F	53.2	Low	52.7	Low	186 Å²	186	132.7 Å²	132.7	82%	0.816	70%	0.699	S	S	*	*			trans	84.1	67.6	164.9	-55.9	-75.7	0	0	0	115.5
10	G	56.8	Low	52.9	Low	63 Å²	63	137.1 Å²	137.1	65%	0.649	71%	0.705	S	S	*	*				71.6	115	104.2	0	0	0	0	0	115.7	P12	G10-P12 WeakPolarHBondContact O-CD 3.38Å
11	V	54.4	Low	53	Low	100 Å²	100	136.2 Å²	136.2	61%	0.606	71%	0.706	S	S	*	*			trans	-104.1	65.3	155.5	-153.4	0	0	0	0	110	W13 L14	V11-W13 PolarHBondContact O-N 3.26Å; V11-L14 HydrophobicContact CG1-CD1 3.67Å; V11-L14 HydrophobicContact CG1-CG 3.59Å; V11-L14 HydrophobicContact CG1-CB 4.03Å
12	P	54.6	Low	53.8	Low	94 Å²	94	134.7 Å²	134.7	61%	0.61	69%	0.685	S	S	*	*	H	α-helix	trans	-71.2	-10.5	166.8	32.5	-32.9	0	0	0	111.4	G10 S16	G10-P12 WeakPolarHBondContact O-CD 3.38Å; P12-S16 PolarHBondContact O-N 3.35Å; P12-S16 PolarHBondContact O-OG 3.06Å
13	W	49.9	Very low	54.3	Low	186 Å²	186	131.7 Å²	131.7	71%	0.705	68%	0.681	S	S	*	*	H	α-helix	trans	-73.7	-42.7	-175.7	-175.6	46.1	0	0	0	113.2	V11 S15 S16 V17	V11-W13 PolarHBondContact O-N 3.26Å; W13-S15 VanDerWaalsContact C-N 3.3Å; W13-S15 PolarHBondContact O-N 3.46Å; W13-S16 WeakPolarHBondContact O-CB 3.02Å; W13-S16 PolarHBondContact O-N 3.26Å; W13-V17 HydrophobicContact CZ2-CG2 4.45Å; W13-V17 WeakPolarHBondContact O-CG2 3.35Å; W13-V17 PolarHBondContact O-N 3.33Å
14	L	53.4	Low	54.9	Low	108 Å²	108	126.3 Å²	126.3	57%	0.565	67%	0.674	S	S	*	*	H	α-helix	trans	-63.9	-37.7	178.3	-70.2	175.7	0	0	0	111.5	V11 S16 V17 V18	V11-L14 HydrophobicContact CG1-CD1 3.67Å; V11-L14 HydrophobicContact CG1-CG 3.59Å; V11-L14 HydrophobicContact CG1-CB 4.03Å; L14-S16 VanDerWaalsContact C-N 3.29Å; L14-S16 PolarHBondContact O-N 3.39Å; L14-V17 PolarHBondContact O-N 3.38Å; L14-V18 WeakPolarHBondContact O-CG2 3.41Å; L14-V18 PolarHBondContact O-N 2.76Å
15	S	53.8	Low	55	Low	80 Å²	80	130.3 Å²	130.3	56%	0.559	69%	0.686	S	S	*	*	H	α-helix	trans	-64.8	-31	173.8	-55.3	0	0	0	0	113.1	W13 R19	W13-S15 VanDerWaalsContact C-N 3.3Å; W13-S15 PolarHBondContact O-N 3.46Å; S15-R19 PolarHBondContact O-N 3.47Å
16	S	52.6	Low	54.9	Low	63 Å²	63	126.2 Å²	126.2	44%	0.441	68%	0.677	S	S	.	*	H	α-helix	trans	-75.6	-34.3	174.5	-76.5	0	0	0	0	112.8	P12 W13 L14	P12-S16 PolarHBondContact O-N 3.35Å; P12-S16 PolarHBondContact O-OG 3.06Å; W13-S16 WeakPolarHBondContact O-CB 3.02Å; W13-S16 PolarHBondContact O-N 3.26Å; L14-S16 VanDerWaalsContact C-N 3.29Å; L14-S16 PolarHBondContact O-N 3.39Å
17	V	54.7	Low	55.1	Low	73 Å²	73	123.3 Å²	123.3	44%	0.442	67%	0.671	S	S	.	*	H	α-helix	trans	-69.3	-43.3	177.9	176	0	0	0	0	110.6	W13 L14 R19 R20	W13-V17 HydrophobicContact CZ2-CG2 4.45Å; W13-V17 WeakPolarHBondContact O-CG2 3.35Å; W13-V17 PolarHBondContact O-N 3.33Å; L14-V17 PolarHBondContact O-N 3.38Å; V17-R19 VanDerWaalsContact C-N 3.3Å; V17-R19 PolarHBondContact O-N 3.23Å; V17-R20 PolarHBondContact O-N 3.39Å
18	V	54.8	Low	55.4	Low	113 Å²	113	123 Å²	123	69%	0.685	67%	0.674	S	S	*	*	H	α-helix	trans	-65.2	-32.6	177.2	174.9	0	0	0	0	112.1	L14 R20	L14-V18 WeakPolarHBondContact O-CG2 3.41Å; L14-V18 PolarHBondContact O-N 2.76Å; V18-R20 VanDerWaalsContact C-N 3.28Å; V18-R20 PolarHBondContact O-N 3.01Å
19	R	53.3	Low	54.9	Low	216 Å²	216	123.4 Å²	123.4	82%	0.815	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.7	-16.6	177.2	-90.4	179.8	141.2	176.7	-4.8	114.8	S15 V17	S15-R19 PolarHBondContact O-N 3.47Å; V17-R19 VanDerWaalsContact C-N 3.3Å; V17-R19 PolarHBondContact O-N 3.23Å
20	R	56.1	Low	55.1	Low	221 Å²	221	120.3 Å²	120.3	83%	0.834	68%	0.677	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.1	-3.5	-179.4	-72.3	-173.4	-170.2	-170.2	3.4	114.2	V17 V18 Q22	V17-R20 PolarHBondContact O-N 3.39Å; V18-R20 VanDerWaalsContact C-N 3.28Å; V18-R20 PolarHBondContact O-N 3.01Å; R20-Q22 PolarHBondContact O-N 3.33Å; R20-Q22 VanDerWaalsContact C-N 3.26Å
21	T	55.1	Low	55.3	Low	118 Å²	118	123 Å²	123	72%	0.724	68%	0.681	S	S	*	*			trans	-97.2	42	169.5	1.8	0	0	0	0	110.5	P23	T21-P23 WeakPolarHBondContact O-CD 3.49Å
22	Q	58.4	Low	55.5	Low	169 Å²	169	122.2 Å²	122.2	79%	0.79	69%	0.685	S	S	*	*			trans	-69.3	118.8	159.6	-143.3	171.6	44.3	0	0	105.4	R20 A24	R20-Q22 PolarHBondContact O-N 3.33Å; R20-Q22 VanDerWaalsContact C-N 3.26Å; Q22-A24 PolarHBondContact O-N 2.99Å
23	P	54.9	Low	55.4	Low	112 Å²	112	122.3 Å²	122.3	73%	0.727	69%	0.688	S	S	*	*			trans	-54.8	122.5	171.3	22.3	-29.6	0	0	0	105.5	T21 H25	T21-P23 WeakPolarHBondContact O-CD 3.49Å; P23-H25 VanDerWaalsContact C-N 3.26Å; P23-H25 PolarHBondContact O-N 3.07Å
24	A	60.3	Low	55.8	Low	86 Å²	86	118.9 Å²	118.9	71%	0.711	69%	0.689	S	S	*	*			trans	-51.7	105.9	168.1	0	0	0	0	0	104.7	Q22 C26	Q22-A24 PolarHBondContact O-N 2.99Å; A24-C26 PolarHBondContact O-N 3.46Å
25	H	53.5	Low	56.4	Low	166 Å²	166	124.7 Å²	124.7	77%	0.769	70%	0.704	S	S	*	*			trans	-65.1	94.6	176.2	-166.4	-127.4	0	0	0	103.3	P23 T27	P23-H25 VanDerWaalsContact C-N 3.26Å; P23-H25 PolarHBondContact O-N 3.07Å; H25-T27 PolarHBondContact O-N 2.73Å
26	C	53.4	Low	56.9	Low	106 Å²	106	126.9 Å²	126.9	72%	0.716	72%	0.716	S	S	*	*			trans	-65.8	83.8	171.7	-66.4	0	0	0	0	105	A24 T28	A24-C26 PolarHBondContact O-N 3.46Å; C26-T28 PolarHBondContact O-N 2.78Å; C26-T28 PolarHBondContact O-OG1 2.74Å
27	T	60.1	Low	57.7	Low	110 Å²	110	134.1 Å²	134.1	68%	0.675	73%	0.734	S	S	*	*			trans	-59.5	94.7	158.1	42.8	0	0	0	0	104.3	H25 S29	H25-T27 PolarHBondContact O-N 2.73Å; T27-S29 PolarHBondContact O-N 2.79Å
28	T	59.8	Low	58	Low	118 Å²	118	136.9 Å²	136.9	72%	0.724	74%	0.742	S	S	*	*			trans	-60.2	97.4	172.2	-53.8	0	0	0	0	104.3	C26 T30	C26-T28 PolarHBondContact O-N 2.78Å; C26-T28 PolarHBondContact O-OG1 2.74Å; T28-T30 PolarHBondContact O-N 2.8Å
29	S	49.3	Very low	58.4	Low	103 Å²	103	143.9 Å²	143.9	72%	0.72	76%	0.756	S	S	*	*			trans	-65	92.5	174.5	-160.9	0	0	0	0	104.9	T27 T31	T27-S29 PolarHBondContact O-N 2.79Å; S29-T31 PolarHBondContact O-N 2.91Å
30	T	57.1	Low	59.1	Low	122 Å²	122	140.9 Å²	140.9	75%	0.748	75%	0.753	S	S	*	*			trans	-64.7	95	171.3	-60.3	0	0	0	0	103.9	T28 A32	T28-T30 PolarHBondContact O-N 2.8Å; T30-A32 PolarHBondContact O-N 2.79Å
31	T	61.8	Low	59.4	Low	120 Å²	120	135.8 Å²	135.8	74%	0.736	75%	0.749	S	S	*	*			trans	-64.3	100.5	172.2	-49.5	0	0	0	0	103.4	S29 S33	S29-T31 PolarHBondContact O-N 2.91Å; T31-S33 PolarHBondContact O-N 2.82Å
32	A	59.2	Low	60.2	Low	83 Å²	83	132.7 Å²	132.7	69%	0.686	74%	0.74	S	S	*	*			trans	-52.3	114.2	173.9	0	0	0	0	0	105.6	T30	T30-A32 PolarHBondContact O-N 2.79Å
33	S	52	Low	60.6	Low	96 Å²	96	130.6 Å²	130.6	67%	0.671	74%	0.741	S	S	*	*			trans	-34.6	129.6	178.7	179.7	0	0	0	0	109.9	T31 R35	T31-S33 PolarHBondContact O-N 2.82Å; S33-R35 PolarHBondContact O-N 2.85Å
34	P	57.6	Low	61.4	Low	113 Å²	113	130.5 Å²	130.5	73%	0.734	74%	0.738	S	S	*	*			trans	-58	112.2	172.4	24.9	-30.7	0	0	0	106	P36	P34-P36 WeakPolarHBondContact O-CD 3.44Å; P34-P36 VanDerWaalsContact O-N 3.14Å
35	R	67.4	Low	61.7	Low	230 Å²	230	133.6 Å²	133.6	87%	0.868	74%	0.742	S	S	*	*			trans	-54.2	124.7	169	-84.8	-174.8	168.1	-173.5	-3	105.5	S33 R37	S33-R35 PolarHBondContact O-N 2.85Å; R35-R37 PolarHBondContact O-N 2.9Å
36	P	62.4	Low	61.8	Low	126 Å²	126	136.8 Å²	136.8	82%	0.818	75%	0.748	S	S	*	*			trans	-59.4	112.5	172.3	23.6	-30	0	0	0	106.4	P34	P34-P36 WeakPolarHBondContact O-CD 3.44Å; P34-P36 VanDerWaalsContact O-N 3.14Å
37	R	69.8	Low	62.1	Low	215 Å²	215	136.7 Å²	136.7	81%	0.811	75%	0.748	S	S	*	*			trans	-61.4	153.1	163.9	-84.7	-178	156.8	-151.1	-2.2	107.3	R35	R35-R37 PolarHBondContact O-N 2.9Å
38	H	61.5	Low	61.8	Low	132 Å²	132	140.4 Å²	140.4	61%	0.611	76%	0.763	S	S	*	*			trans	95.1	99.5	163.9	-57	-83.2	0	0	0	115.4
39	W	63.6	Low	61.3	Low	259 Å²	259	142.7 Å²	142.7	98%	0.981	79%	0.794	S	S	*	*				-133.1	131.6	97.6	-67.3	87.9	0	0	0	109.2
40	M	67.1	Low	61.9	Low	153 Å²	153	144.7 Å²	144.7	75%	0.754	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-70.4	149.3	179.1	-64.6	-132.9	78.7	0	0	110.6	G42	M40-G42 PolarHBondContact O-N 3.12Å; M40-G42 VanDerWaalsContact O-N 3.12Å
41	P	63.5	Low	62.2	Low	115 Å²	115	145.8 Å²	145.8	75%	0.747	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-60	120	160	26	-29.1	0	0	0	107.1
42	G	71	Confident	62.2	Low	52 Å²	52	147.3 Å²	147.3	54%	0.536	80%	0.803	S	S	.	*	P	Polyproline II helix	trans	-55.9	162.5	172	0	0	0	0	0	110.3	M40 T44	M40-G42 PolarHBondContact O-N 3.12Å; M40-G42 VanDerWaalsContact O-N 3.12Å; G42-T44 PolarHBondContact O-N 2.93Å
43	P	68	Low	62.4	Low	126 Å²	126	151.1 Å²	151.1	82%	0.818	81%	0.81	S	S	*	*			trans	-55.7	115.4	177.2	24	-32.4	0	0	0	108.8	L45	P43-L45 PolarHBondContact O-N 2.93Å
44	T	70.4	Confident	63	Low	109 Å²	109	154.5 Å²	154.5	67%	0.669	82%	0.819	S	S	*	*			trans	-60.4	103.9	167.9	-54.4	0	0	0	0	106	G42 W46	G42-T44 PolarHBondContact O-N 2.93Å; T44-W46 PolarHBondContact O-N 3.3Å
45	L	66.6	Low	63.4	Low	151 Å²	151	157.3 Å²	157.3	79%	0.791	83%	0.825	S	S	*	*			trans	-63.3	93.2	164.2	-69	172.8	0	0	0	105.8	P43 S47	P43-L45 PolarHBondContact O-N 2.93Å; L45-S47 VanDerWaalsContact C-N 3.26Å; L45-S47 PolarHBondContact O-N 2.86Å
46	W	56	Low	63.1	Low	234 Å²	234	152.1 Å²	152.1	89%	0.886	82%	0.821	S	S	*	*			trans	-57.8	103.2	162.3	-82.1	58.5	0	0	0	105	T44 L48	T44-W46 PolarHBondContact O-N 3.3Å; W46-L48 PolarHBondContact O-N 2.83Å
47	S	59.1	Low	63.2	Low	104 Å²	104	154.1 Å²	154.1	73%	0.727	82%	0.822	S	S	*	*			trans	-58.5	126.4	-178.6	-67	0	0	0	0	107.6	L45 A49	L45-S47 VanDerWaalsContact C-N 3.26Å; L45-S47 PolarHBondContact O-N 2.86Å; S47-A49 PolarHBondContact O-N 3.04Å
48	L	54.4	Low	62.6	Low	187 Å²	187	149 Å²	149	98%	0.979	82%	0.823	S	S	*	*			trans	-61.3	107.6	160.5	-83.2	105.3	0	0	0	107	W46	W46-L48 PolarHBondContact O-N 2.83Å
49	A	50	Low	62.7	Low	166 Å²	166	150.5 Å²	150.5	100%	1.372	84%	0.842	S	S	*	*			trans	-142	0	164.2	0	0	0	0	0	107.7	S47	S47-A49 PolarHBondContact O-N 3.04Å

Retrieved 49 of 49 residues in 39.5 ms (Link to these results)

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