A0A087WX93_HUMAN Loading...

TIA1 cytotoxic granule associated RNA binding protein like 1

AlphaFold DB , UniProt , Accession A0A087WX93, Species HUMAN (Homo sapiens, Human), Gene TIAL1, Length 28 aa.

						>A0A087WX93_HUMAN|A0A087WX93|TIAL1
MMEDDGQPRTLHTQAKTYGSIFRKQYGV
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	69.4	Low	59.2	Low	246 Å²	246	146.6 Å²	146.6	100%	1.212	77%	0.771	S	S	*	*				0	95.9	0	-82.2	-179.9	-176.2	0	0	107.4
2	M	57.3	Low	58.9	Low	188 Å²	188	144.4 Å²	144.4	93%	0.926	75%	0.753	S	S	*	*			trans	-168.7	148.1	160.3	-99.8	175.4	-166	0	0	106
3	E	63.1	Low	58.9	Low	191 Å²	191	139.4 Å²	139.4	89%	0.893	73%	0.732	S	S	*	*			trans	-45.9	143	-170	-74.6	153.3	85	0	0	115.8
4	D	59.6	Low	58.8	Low	157 Å²	157	136.1 Å²	136.1	84%	0.84	71%	0.712	S	S	*	*			trans	-126.6	125.4	168.3	-138.8	-76.4	0	0	0	108.1	G6	D4-G6 PolarHBondContact O-N 2.97Å; D4-G6 VanDerWaalsContact C-N 3.32Å
5	D	64.1	Low	59	Low	167 Å²	167	131.3 Å²	131.3	89%	0.893	70%	0.699	S	S	*	*			trans	-56.9	80.9	-176.4	-70.4	-75.2	0	0	0	113.2	Q7	D5-Q7 PolarHBondContact O-N 3.2Å
6	G	55.7	Low	59.2	Low	69 Å²	69	131.1 Å²	131.1	71%	0.711	69%	0.69	S	S	*	*			trans	-95.2	77.6	175.3	0	0	0	0	0	111.7	D4	D4-G6 PolarHBondContact O-N 2.97Å; D4-G6 VanDerWaalsContact C-N 3.32Å
7	Q	55.3	Low	59.4	Low	120 Å²	120	127.2 Å²	127.2	56%	0.561	67%	0.673	S	S	*	*			trans	17.1	133.5	153	-164.8	177.1	21.1	0	0	117	D5 R9	D5-Q7 PolarHBondContact O-N 3.2Å; Q7-R9 HydrophobicContact CB-CG 3.9Å; Q7-R9 VanDerWaalsContact CD-CG 3.44Å; Q7-R9 HydrophobicContact CG-CG 3.56Å; Q7-R9 PolarHBondContact O-N 2.89Å; Q7-R9 VanDerWaalsContact OE1-CG 3.29Å
8	P	57.2	Low	59.6	Low	99 Å²	99	128.9 Å²	128.9	64%	0.643	67%	0.67	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.1	38.2	176	31.4	-36.9	0	0	0	114.2	T10	P8-T10 PolarHBondContact O-N 3.45Å
9	R	56.6	Low	60	Low	166 Å²	166	124.4 Å²	124.4	63%	0.626	66%	0.658	S	S	*	*	H	α-helix	trans	-59.8	-24.3	167.9	-56.5	-177.2	91.3	127.4	-11.5	111.2	Q7 T13	Q7-R9 HydrophobicContact CB-CG 3.9Å; Q7-R9 VanDerWaalsContact CD-CG 3.44Å; Q7-R9 HydrophobicContact CG-CG 3.56Å; Q7-R9 PolarHBondContact O-N 2.89Å; Q7-R9 VanDerWaalsContact OE1-CG 3.29Å; R9-T13 WeakPolarHBondContact O-CB 3.35Å; R9-T13 PolarHBondContact O-OG1 3.36Å; R9-T13 PolarHBondContact O-N 2.95Å
10	T	56.9	Low	60.5	Low	87 Å²	87	121.2 Å²	121.2	53%	0.534	65%	0.646	S	S	.	*	H	α-helix	trans	-67.4	-46.5	-176.6	52.2	0	0	0	0	111.3	P8 Q14	P8-T10 PolarHBondContact O-N 3.45Å; T10-Q14 WeakPolarHBondContact O-CB 3.07Å; T10-Q14 WeakPolarHBondContact O-CG 3.42Å; T10-Q14 PolarHBondContact O-N 2.91Å
11	L	55.7	Low	61	Low	123 Å²	123	118.9 Å²	118.9	64%	0.644	63%	0.633	S	S	*	*	H	α-helix	trans	-72.4	-44.3	-179.1	-66.5	174.7	0	0	0	113.1	T13 Q14 A15	L11-T13 PolarHBondContact O-N 3.25Å; L11-Q14 PolarHBondContact O-N 2.99Å; L11-A15 WeakPolarHBondContact O-CB 3.46Å; L11-A15 PolarHBondContact O-N 3.43Å; L11-A15 VanDerWaalsContact O-CB 3.24Å
12	H	56.5	Low	61	Low	120 Å²	120	113.6 Å²	113.6	56%	0.556	60%	0.604	S	S	*	*	H	α-helix	trans	-67.3	-37.1	179.3	-169.4	59.6	0	0	0	112.4	K16	H12-K16 VanDerWaalsContact NE2-CE 3.29Å; H12-K16 WeakPolarHBondContact NE2-CE 3.13Å; H12-K16 PolarHBondContact NE2-NZ 3.27Å; H12-K16 WeakPolarHBondContact O-CB 3.48Å; H12-K16 WeakPolarHBondContact O-CG 3.29Å; H12-K16 PolarHBondContact O-N 3.49Å; H12-K16 VanDerWaalsContact O-N 3.08Å
13	T	58.5	Low	62	Low	79 Å²	79	114.2 Å²	114.2	49%	0.485	60%	0.596	S	S	.	*	H	α-helix	trans	-74.2	-39.9	178	-52.4	0	0	0	0	111	R9 L11 T17	R9-T13 WeakPolarHBondContact O-CB 3.35Å; R9-T13 PolarHBondContact O-OG1 3.36Å; R9-T13 PolarHBondContact O-N 2.95Å; L11-T13 PolarHBondContact O-N 3.25Å; T13-T17 PolarHBondContact O-N 2.94Å; T13-T17 PolarHBondContact O-OG1 3.06Å; T13-T17 WeakPolarHBondContact O-CB 3.24Å
14	Q	58.2	Low	62.5	Low	94 Å²	94	114 Å²	114	44%	0.439	59%	0.592	S	S	.	*	H	α-helix	trans	-62	-50.4	172.9	-78.1	175.3	26.9	0	0	110.8	T10 L11 K16 T17 Y18	T10-Q14 WeakPolarHBondContact O-CB 3.07Å; T10-Q14 WeakPolarHBondContact O-CG 3.42Å; T10-Q14 PolarHBondContact O-N 2.91Å; L11-Q14 PolarHBondContact O-N 2.99Å; Q14-K16 VanDerWaalsContact C-N 3.33Å; Q14-K16 PolarHBondContact O-N 2.85Å; Q14-T17 WeakPolarHBondContact O-CA 2.99Å; Q14-T17 WeakPolarHBondContact O-CB 3.46Å; Q14-T17 PolarHBondContact O-N 3.11Å; Q14-Y18 PolarHBondContact O-N 3.34Å; Q14-Y18 WeakPolarHBondContact O-CD2 3.5Å; Q14-Y18 HydrophobicContact CB-CE2 3.82Å; Q14-Y18 HydrophobicContact CG-CE2 4.16Å; Q14-Y18 HydrophobicContact CB-CD2 4.03Å
15	A	60.8	Low	63.1	Low	63 Å²	63	112.5 Å²	112.5	52%	0.521	58%	0.58	S	S	.	*	H	α-helix	trans	-58.9	-41.1	179.4	0	0	0	0	0	112.8	L11 G19	L11-A15 WeakPolarHBondContact O-CB 3.46Å; L11-A15 PolarHBondContact O-N 3.43Å; L11-A15 VanDerWaalsContact O-CB 3.24Å; A15-G19 PolarHBondContact O-N 3.08Å
16	K	61.8	Low	63.9	Low	129 Å²	129	111.7 Å²	111.7	56%	0.561	57%	0.565	S	S	*	*	H	α-helix	trans	-63.5	-41.5	172.4	-78.6	179.9	175.5	-176.6	0	112.6	H12 Q14 S20	H12-K16 VanDerWaalsContact NE2-CE 3.29Å; H12-K16 WeakPolarHBondContact NE2-CE 3.13Å; H12-K16 PolarHBondContact NE2-NZ 3.27Å; H12-K16 WeakPolarHBondContact O-CB 3.48Å; H12-K16 WeakPolarHBondContact O-CG 3.29Å; H12-K16 PolarHBondContact O-N 3.49Å; H12-K16 VanDerWaalsContact O-N 3.08Å; Q14-K16 VanDerWaalsContact C-N 3.33Å; Q14-K16 PolarHBondContact O-N 2.85Å; K16-S20 WeakPolarHBondContact O-CB 3.34Å; K16-S20 PolarHBondContact O-N 2.92Å; K16-S20 PolarHBondContact O-OG 3.47Å
17	T	63.5	Low	64.2	Low	65 Å²	65	110.8 Å²	110.8	40%	0.399	56%	0.556	S	S	.	*	H	α-helix	trans	-64.9	-54.1	179.7	-57.5	0	0	0	0	110.1	T13 Q14 G19 S20 I21	T13-T17 PolarHBondContact O-N 2.94Å; T13-T17 PolarHBondContact O-OG1 3.06Å; T13-T17 WeakPolarHBondContact O-CB 3.24Å; Q14-T17 WeakPolarHBondContact O-CA 2.99Å; Q14-T17 WeakPolarHBondContact O-CB 3.46Å; Q14-T17 PolarHBondContact O-N 3.11Å; T17-G19 PolarHBondContact O-N 2.83Å; T17-S20 PolarHBondContact O-N 3.27Å; T17-S20 PolarHBondContact O-OG 2.96Å; T17-I21 WeakPolarHBondContact O-CB 3.43Å; T17-I21 PolarHBondContact O-N 3.18Å; T17-I21 WeakPolarHBondContact O-CG1 3.22Å; T17-I21 WeakPolarHBondContact O-CD1 3.47Å; T17-I21 HydrophobicContact CG2-CD1 3.7Å
18	Y	63.5	Low	64.4	Low	157 Å²	157	115.4 Å²	115.4	62%	0.616	59%	0.592	S	S	*	*	H	α-helix	trans	-62.6	-42.8	178.8	-67.3	-65	0	0	0	112.5	Q14 S20 I21 F22	Q14-Y18 PolarHBondContact O-N 3.34Å; Q14-Y18 WeakPolarHBondContact O-CD2 3.5Å; Q14-Y18 HydrophobicContact CB-CE2 3.82Å; Q14-Y18 HydrophobicContact CG-CE2 4.16Å; Q14-Y18 HydrophobicContact CB-CD2 4.03Å; Y18-S20 PolarHBondContact O-N 3.48Å; Y18-I21 PolarHBondContact O-N 3.33Å; Y18-F22 WeakPolarHBondContact O-CB 3.44Å; Y18-F22 PolarHBondContact O-N 2.99Å
19	G	66.9	Low	64.8	Low	43 Å²	43	116.2 Å²	116.2	44%	0.443	59%	0.589	S	S	.	*	H	α-helix	trans	-64.9	-37.1	176.6	0	0	0	0	0	113.5	A15 T17 R23	A15-G19 PolarHBondContact O-N 3.08Å; T17-G19 PolarHBondContact O-N 2.83Å; G19-R23 PolarHBondContact O-N 3.02Å
20	S	69.5	Low	65.2	Low	61 Å²	61	113.6 Å²	113.6	43%	0.427	59%	0.587	S	S	.	*	H	α-helix	trans	-69.5	-38.4	175.6	74.6	0	0	0	0	112.6	K16 T17 Y18 K24	K16-S20 WeakPolarHBondContact O-CB 3.34Å; K16-S20 PolarHBondContact O-N 2.92Å; K16-S20 PolarHBondContact O-OG 3.47Å; T17-S20 PolarHBondContact O-N 3.27Å; T17-S20 PolarHBondContact O-OG 2.96Å; Y18-S20 PolarHBondContact O-N 3.48Å; S20-K24 PolarHBondContact O-N 2.8Å; S20-K24 WeakPolarHBondContact O-CG 3.03Å
21	I	70.1	Confident	65.7	Low	72 Å²	72	115.1 Å²	115.1	37%	0.369	59%	0.59	S	S	.	*	H	α-helix	trans	-69.1	-44.1	179.2	-70.9	166.8	0	0	0	110.4	T17 Y18 K24 Q25	T17-I21 WeakPolarHBondContact O-CB 3.43Å; T17-I21 PolarHBondContact O-N 3.18Å; T17-I21 WeakPolarHBondContact O-CG1 3.22Å; T17-I21 WeakPolarHBondContact O-CD1 3.47Å; T17-I21 HydrophobicContact CG2-CD1 3.7Å; Y18-I21 PolarHBondContact O-N 3.33Å; I21-K24 PolarHBondContact O-N 2.63Å; I21-Q25 WeakPolarHBondContact O-CB 3.19Å; I21-Q25 WeakPolarHBondContact O-CG 3.46Å; I21-Q25 PolarHBondContact O-N 2.61Å
22	F	71.1	Confident	66.2	Low	135 Å²	135	114.6 Å²	114.6	59%	0.592	59%	0.587	S	S	*	*	H	α-helix	trans	-60.6	-46.3	177.2	-176.6	-96.3	0	0	0	111.8	Y18 K24 Q25 Y26	Y18-F22 WeakPolarHBondContact O-CB 3.44Å; Y18-F22 PolarHBondContact O-N 2.99Å; F22-K24 VanDerWaalsContact C-N 3.35Å; F22-K24 PolarHBondContact O-N 3.26Å; F22-Q25 PolarHBondContact O-N 3.06Å; F22-Y26 HydrophobicContact CD2-CE2 4.18Å; F22-Y26 PolarHBondContact O-N 2.71Å; F22-Y26 HydrophobicContact CG-CD2 4.32Å; F22-Y26 HydrophobicContact CE2-CG 4.31Å; F22-Y26 HydrophobicContact CE2-CE2 4.39Å; F22-Y26 HydrophobicContact CE2-CD2 3.72Å; F22-Y26 AromaticContact CE2-CD2 3.72Å; F22-Y26 HydrophobicContact CD2-CD2 3.61Å; F22-Y26 AromaticContact CD2-CD2 3.61Å
23	R	77.2	Confident	66.9	Low	201 Å²	201	114.3 Å²	114.3	76%	0.758	59%	0.589	S	S	*	*	H	α-helix	trans	-60.3	-40.9	175.1	-175.7	-175.8	-67.3	-129.7	-0.8	112.5	G19 G27	G19-R23 PolarHBondContact O-N 3.02Å; R23-G27 WeakPolarHBondContact O-CA 3.35Å; R23-G27 PolarHBondContact O-N 2.79Å; R23-G27 VanDerWaalsContact O-N 3.11Å
24	K	72.9	Confident	67.4	Low	188 Å²	188	116.6 Å²	116.6	82%	0.817	60%	0.596	S	S	*	*	H	α-helix	trans	-67.1	-34.3	177.4	-80.6	-172.8	176.6	-173.2	0	113.2	S20 I21 F22	S20-K24 PolarHBondContact O-N 2.8Å; S20-K24 WeakPolarHBondContact O-CG 3.03Å; I21-K24 PolarHBondContact O-N 2.63Å; F22-K24 VanDerWaalsContact C-N 3.35Å; F22-K24 PolarHBondContact O-N 3.26Å
25	Q	73.3	Confident	68.1	Low	125 Å²	125	118.2 Å²	118.2	58%	0.584	61%	0.607	S	S	*	*	H	α-helix	trans	-90.2	-34	-174.2	-74.3	-173.8	104.6	0	0	114	I21 F22	I21-Q25 WeakPolarHBondContact O-CB 3.19Å; I21-Q25 WeakPolarHBondContact O-CG 3.46Å; I21-Q25 PolarHBondContact O-N 2.61Å; F22-Q25 PolarHBondContact O-N 3.06Å
26	Y	81.3	Confident	68.6	Low	150 Å²	150	122.5 Å²	122.5	59%	0.588	61%	0.614	S	S	*	*	H	α-helix	trans	-131.8	11.3	-170.2	-52.1	-75.1	0	0	0	113.7	F22 V28	F22-Y26 HydrophobicContact CD2-CE2 4.18Å; F22-Y26 PolarHBondContact O-N 2.71Å; F22-Y26 HydrophobicContact CG-CD2 4.32Å; F22-Y26 HydrophobicContact CE2-CG 4.31Å; F22-Y26 HydrophobicContact CE2-CE2 4.39Å; F22-Y26 HydrophobicContact CE2-CD2 3.72Å; F22-Y26 AromaticContact CE2-CD2 3.72Å; F22-Y26 HydrophobicContact CD2-CD2 3.61Å; F22-Y26 AromaticContact CD2-CD2 3.61Å; Y26-V28 PolarHBondContact O-N 3.38Å
27	G	61	Low	69.2	Low	50 Å²	50	121.9 Å²	121.9	52%	0.515	62%	0.618	S	S	.	*			trans	-51.7	112.6	178.1	0	0	0	0	0	110.7	R23	R23-G27 WeakPolarHBondContact O-CA 3.35Å; R23-G27 PolarHBondContact O-N 2.79Å; R23-G27 VanDerWaalsContact O-N 3.11Å
28	V	60	Low	69.7	Low	216 Å²	216	127.1 Å²	127.1	100%	1.309	64%	0.638	S	S	*	*			trans	-53	0	151	-177.6	0	0	0	0	108.1	Y26	Y26-V28 PolarHBondContact O-N 3.38Å

Retrieved 28 of 28 residues in 24 ms (Link to these results)

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