A0A087WZ34_HUMAN Loading...

Centrosomal protein 250

AlphaFold DB , UniProt , Accession A0A087WZ34, Species HUMAN (Homo sapiens, Human), Gene CEP250, Length 34 aa.

						>A0A087WZ34_HUMAN|A0A087WZ34|CEP250
DGRGQKNSDAKCVAELQKEGRAHGKWHADSDTGH
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	D	48.8	Very low	61.9	Low	165 Å²	165	111.8 Å²	111.8	88%	0.882	61%	0.613	S	S	*	*				0	97	0	-81.6	-105.3	0	0	0	114	R3	D1-R3 VanDerWaalsContact O-N 3.14Å; D1-R3 IonicContact OD1-CZ 3.14Å; D1-R3 IonicContact OD1-NE 2.86Å; D1-R3 PolarHBondContact OD1-NE 3.44Å; D1-R3 IonicContact OD1-NH2 2.68Å; D1-R3 PolarHBondContact OD1-NH2 2.89Å; D1-R3 PolarHBondContact O-N 3.14Å
2	G	56.2	Low	63	Low	65 Å²	65	107.8 Å²	107.8	67%	0.67	60%	0.597	S	S	*	*			trans	-81.6	31	177.9	0	0	0	0	0	115.1	G4	G2-G4 VanDerWaalsContact C-N 3.27Å; G2-G4 PolarHBondContact O-N 2.68Å
3	R	54.2	Low	64.1	Low	191 Å²	191	105.2 Å²	105.2	72%	0.721	59%	0.586	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.2	-8.7	-176	-65.8	-176.2	-85.8	168.2	-2.5	113.5	D1 N7	D1-R3 VanDerWaalsContact O-N 3.14Å; D1-R3 IonicContact OD1-CZ 3.14Å; D1-R3 IonicContact OD1-NE 2.86Å; D1-R3 PolarHBondContact OD1-NE 3.44Å; D1-R3 IonicContact OD1-NH2 2.68Å; D1-R3 PolarHBondContact OD1-NH2 2.89Å; D1-R3 PolarHBondContact O-N 3.14Å; R3-N7 PolarHBondContact O-ND2 2.86Å
4	G	59	Low	65	Low	51 Å²	51	101.4 Å²	101.4	53%	0.526	58%	0.575	S	S	.	*	T	Hydrogen-bonded Turn	trans	-77.9	-26.5	-175.9	0	0	0	0	0	116.1	G2 N7	G2-G4 VanDerWaalsContact C-N 3.27Å; G2-G4 PolarHBondContact O-N 2.68Å; G4-N7 WeakPolarHBondContact CA-ND2 3.24Å; G4-N7 PolarHBondContact O-OD1 2.84Å; G4-N7 PolarHBondContact O-ND2 3.29Å
5	Q	56.5	Low	65.8	Low	148 Å²	148	100.6 Å²	100.6	69%	0.692	56%	0.564	S	S	*	*	H	α-helix	trans	-89.3	-37.9	-172.7	-169.7	171.1	61	0	0	112.7	N7 S8 D9	Q5-N7 PolarHBondContact O-N 3.28Å; Q5-S8 PolarHBondContact O-N 2.69Å; Q5-S8 VanDerWaalsContact O-N 3.14Å; Q5-S8 PolarHBondContact O-OG 3.32Å; Q5-D9 PolarHBondContact O-N 3.14Å
6	K	56.7	Low	66.2	Low	164 Å²	164	101.1 Å²	101.1	71%	0.713	57%	0.565	S	S	*	*	H	α-helix	trans	-66	-25.8	-178.2	-60.7	-177.9	179.1	-175.8	0	113.4	A10	K6-A10 PolarHBondContact O-N 3.21Å
7	N	62.3	Low	66.4	Low	96 Å²	96	103.3 Å²	103.3	51%	0.513	57%	0.57	S	S	.	*	H	α-helix	trans	-77.3	-30.3	177.4	65.3	72.4	0	0	0	112.1	R3 G4 Q5 K11	R3-N7 PolarHBondContact O-ND2 2.86Å; G4-N7 WeakPolarHBondContact CA-ND2 3.24Å; G4-N7 PolarHBondContact O-OD1 2.84Å; G4-N7 PolarHBondContact O-ND2 3.29Å; Q5-N7 PolarHBondContact O-N 3.28Å; N7-K11 VanDerWaalsContact O-CB 3.29Å; N7-K11 PolarHBondContact O-N 3.37Å; N7-K11 WeakPolarHBondContact O-CB 3.29Å
8	S	64	Low	66.5	Low	60 Å²	60	107.7 Å²	107.7	42%	0.42	58%	0.582	S	S	.	*	H	α-helix	trans	-69.3	-36	174.2	48.4	0	0	0	0	111.8	Q5 C12	Q5-S8 PolarHBondContact O-N 2.69Å; Q5-S8 VanDerWaalsContact O-N 3.14Å; Q5-S8 PolarHBondContact O-OG 3.32Å; S8-C12 WeakPolarHBondContact O-CB 3.48Å; S8-C12 PolarHBondContact O-N 3.01Å
9	D	70.5	Confident	66.2	Low	96 Å²	96	110.3 Å²	110.3	51%	0.513	59%	0.59	S	S	.	*	H	α-helix	trans	-65.9	-47	175.3	-61.7	-59.9	0	0	0	111.5	Q5 K11 C12 V13	Q5-D9 PolarHBondContact O-N 3.14Å; D9-K11 VanDerWaalsContact C-N 3.31Å; D9-K11 PolarHBondContact O-N 2.89Å; D9-C12 PolarHBondContact O-N 3.03Å; D9-V13 WeakPolarHBondContact O-CG2 3.29Å; D9-V13 PolarHBondContact O-N 2.88Å; D9-V13 VanDerWaalsContact O-CG2 3.29Å; D9-V13 WeakPolarHBondContact O-CB 3.19Å
10	A	73.8	Confident	65.8	Low	63 Å²	63	106.1 Å²	106.1	52%	0.521	57%	0.574	S	S	.	*	H	α-helix	trans	-63.1	-38.5	178.7	0	0	0	0	0	112.2	K6 A14	K6-A10 PolarHBondContact O-N 3.21Å; A10-A14 WeakPolarHBondContact O-CB 3.39Å; A10-A14 PolarHBondContact O-N 3.41Å
11	K	79.2	Confident	65.1	Low	131 Å²	131	112.5 Å²	112.5	57%	0.57	59%	0.59	S	S	*	*	H	α-helix	trans	-68.9	-44.4	176.5	-162.4	-164.8	170.9	-167.3	0	111.5	N7 D9 V13 A14 E15	N7-K11 VanDerWaalsContact O-CB 3.29Å; N7-K11 PolarHBondContact O-N 3.37Å; N7-K11 WeakPolarHBondContact O-CB 3.29Å; D9-K11 VanDerWaalsContact C-N 3.31Å; D9-K11 PolarHBondContact O-N 2.89Å; K11-V13 PolarHBondContact O-N 3.44Å; K11-A14 PolarHBondContact O-N 2.88Å; K11-E15 PolarHBondContact O-N 3.19Å; K11-E15 WeakPolarHBondContact O-CG 3.23Å; K11-E15 IonicContact NZ-OE2 3.99Å; K11-E15 WeakPolarHBondContact CE-OE2 3.28Å; K11-E15 WeakPolarHBondContact CG-OE2 3.38Å; K11-E15 VanDerWaalsContact CE-OE2 3.31Å
12	C	75.3	Confident	65.4	Low	63 Å²	63	109.3 Å²	109.3	43%	0.426	59%	0.586	S	S	.	*	H	α-helix	trans	-59.3	-46	175.5	-178.9	0	0	0	0	111.5	S8 D9 A14 E15 L16	S8-C12 WeakPolarHBondContact O-CB 3.48Å; S8-C12 PolarHBondContact O-N 3.01Å; D9-C12 PolarHBondContact O-N 3.03Å; C12-A14 VanDerWaalsContact C-N 3.34Å; C12-A14 PolarHBondContact O-N 3.47Å; C12-E15 PolarHBondContact O-N 2.83Å; C12-L16 WeakPolarHBondContact O-CB 3.35Å; C12-L16 VanDerWaalsContact O-CG 3.23Å; C12-L16 WeakPolarHBondContact O-CG 3.31Å; C12-L16 PolarHBondContact O-N 3.3Å
13	V	77.1	Confident	65.7	Low	75 Å²	75	112.9 Å²	112.9	46%	0.455	59%	0.586	S	S	.	*	H	α-helix	trans	-62.6	-40.4	176.1	171.4	0	0	0	0	111.5	D9 K11 L16 Q17	D9-V13 WeakPolarHBondContact O-CG2 3.29Å; D9-V13 PolarHBondContact O-N 2.88Å; D9-V13 VanDerWaalsContact O-CG2 3.29Å; D9-V13 WeakPolarHBondContact O-CB 3.19Å; K11-V13 PolarHBondContact O-N 3.44Å; V13-L16 PolarHBondContact O-N 2.83Å; V13-Q17 HydrophobicContact CG1-CG 4.41Å; V13-Q17 PolarHBondContact O-N 3.46Å; V13-Q17 WeakPolarHBondContact O-CG 3.02Å; V13-Q17 VanDerWaalsContact O-CG 3.25Å; V13-Q17 WeakPolarHBondContact O-CB 3.38Å
14	A	76.1	Confident	66.1	Low	52 Å²	52	107 Å²	107	43%	0.43	59%	0.585	S	S	.	*	H	α-helix	trans	-67.1	-39	177.1	0	0	0	0	0	112.6	A10 K11 C12 Q17 K18	A10-A14 WeakPolarHBondContact O-CB 3.39Å; A10-A14 PolarHBondContact O-N 3.41Å; K11-A14 PolarHBondContact O-N 2.88Å; C12-A14 VanDerWaalsContact C-N 3.34Å; C12-A14 PolarHBondContact O-N 3.47Å; A14-Q17 PolarHBondContact O-N 2.93Å; A14-K18 VanDerWaalsContact O-CB 3.28Å; A14-K18 WeakPolarHBondContact O-CB 3.37Å; A14-K18 PolarHBondContact O-N 3.41Å
15	E	76.8	Confident	66.3	Low	89 Å²	89	113.2 Å²	113.2	42%	0.416	60%	0.597	S	S	.	*	H	α-helix	trans	-65.4	-45.8	174.1	-71.7	177	96.2	0	0	110.6	K11 C12 Q17 K18 E19	K11-E15 PolarHBondContact O-N 3.19Å; K11-E15 WeakPolarHBondContact O-CG 3.23Å; K11-E15 IonicContact NZ-OE2 3.99Å; K11-E15 WeakPolarHBondContact CE-OE2 3.28Å; K11-E15 WeakPolarHBondContact CG-OE2 3.38Å; K11-E15 VanDerWaalsContact CE-OE2 3.31Å; C12-E15 PolarHBondContact O-N 2.83Å; E15-Q17 PolarHBondContact O-N 2.9Å; E15-Q17 VanDerWaalsContact C-N 3.33Å; E15-K18 PolarHBondContact O-N 2.73Å; E15-E19 WeakPolarHBondContact O-CB 3.38Å; E15-E19 WeakPolarHBondContact O-CG 3.25Å; E15-E19 PolarHBondContact O-N 2.83Å
16	L	72.2	Confident	66.6	Low	109 Å²	109	116 Å²	116	57%	0.571	60%	0.601	S	S	*	*	H	α-helix	trans	-63.6	-32.5	173.9	-70.4	173	0	0	0	113.3	C12 V13 G20	C12-L16 WeakPolarHBondContact O-CB 3.35Å; C12-L16 VanDerWaalsContact O-CG 3.23Å; C12-L16 WeakPolarHBondContact O-CG 3.31Å; C12-L16 PolarHBondContact O-N 3.3Å; V13-L16 PolarHBondContact O-N 2.83Å; L16-G20 WeakPolarHBondContact O-CA 3.39Å; L16-G20 PolarHBondContact O-N 3.19Å
17	Q	69.8	Low	67	Low	138 Å²	138	115.3 Å²	115.3	65%	0.645	60%	0.6	S	S	*	*	H	α-helix	trans	-73.3	-38.1	173.5	-78	176	5.2	0	0	112	V13 A14 E15 G20 R21	V13-Q17 HydrophobicContact CG1-CG 4.41Å; V13-Q17 PolarHBondContact O-N 3.46Å; V13-Q17 WeakPolarHBondContact O-CG 3.02Å; V13-Q17 VanDerWaalsContact O-CG 3.25Å; V13-Q17 WeakPolarHBondContact O-CB 3.38Å; A14-Q17 PolarHBondContact O-N 2.93Å; E15-Q17 PolarHBondContact O-N 2.9Å; E15-Q17 VanDerWaalsContact C-N 3.33Å; Q17-G20 CarbonylContact O-C 3.54Å; Q17-R21 PolarHBondContact O-N 2.91Å
18	K	69.4	Low	67.1	Low	182 Å²	182	115.1 Å²	115.1	79%	0.791	61%	0.612	S	S	*	*	H	α-helix	trans	-69	-42.3	178.6	-174.7	-176.5	176.6	-172.4	0	111.5	A14 E15	A14-K18 VanDerWaalsContact O-CB 3.28Å; A14-K18 WeakPolarHBondContact O-CB 3.37Å; A14-K18 PolarHBondContact O-N 3.41Å; E15-K18 PolarHBondContact O-N 2.73Å
19	E	59.3	Low	67.2	Low	157 Å²	157	118.8 Å²	118.8	73%	0.734	63%	0.627	S	S	*	*	H	α-helix	trans	-81.9	-27.2	176.3	-63.9	180	174	0	0	111.4	E15	E15-E19 WeakPolarHBondContact O-CB 3.38Å; E15-E19 WeakPolarHBondContact O-CG 3.25Å; E15-E19 PolarHBondContact O-N 2.83Å
20	G	58.7	Low	66.9	Low	27 Å²	27	118.9 Å²	118.9	28%	0.278	64%	0.635	S	S	.	*			trans	-97.2	29	-178.5	0	0	0	0	0	115.5	L16 Q17 A22 H23	L16-G20 WeakPolarHBondContact O-CA 3.39Å; L16-G20 PolarHBondContact O-N 3.19Å; Q17-G20 CarbonylContact O-C 3.54Å; G20-A22 PolarHBondContact O-N 3.39Å; G20-H23 PolarHBondContact O-N 3.3Å
21	R	51.1	Low	66.3	Low	241 Å²	241	123.7 Å²	123.7	91%	0.909	65%	0.652	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.4	-8.9	162	-176.9	166.3	172.1	158.2	-1.8	112.6	Q17	Q17-R21 PolarHBondContact O-N 2.91Å
22	A	56.1	Low	65.7	Low	97 Å²	97	124.4 Å²	124.4	80%	0.802	67%	0.668	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.7	-9.5	171.9	0	0	0	0	0	115.5	G20	G20-A22 PolarHBondContact O-N 3.39Å
23	H	62	Low	65.4	Low	141 Å²	141	124.2 Å²	124.2	65%	0.653	68%	0.677	S	S	*	*			trans	-105.7	34.1	-177.1	-152	-91.6	0	0	0	113.2	G20 W26	G20-H23 PolarHBondContact O-N 3.3Å; H23-W26 AromaticContact CD2-NE1 3.74Å; H23-W26 PolarHBondContact NE2-NE1 2.96Å; H23-W26 AromaticContact NE2-NE1 2.98Å; H23-W26 AromaticContact NE2-CD1 3.52Å; H23-W26 AromaticContact CE1-NE1 3.74Å; H23-W26 AromaticContact CE1-CD1 3.88Å
24	G	62.8	Low	63.8	Low	68 Å²	68	133.3 Å²	133.3	70%	0.701	71%	0.714	S	S	*	*	S	Bend	trans	-101.9	96	168.2	0	0	0	0	0	109.7
25	K	62.3	Low	63.2	Low	181 Å²	181	137.4 Å²	137.4	79%	0.787	73%	0.728	S	S	*	*			trans	84.6	86	170.8	-149.8	168.4	-172.5	-77.9	0	115.1	H27	K25-H27 PolarHBondContact O-N 2.99Å
26	W	63.9	Low	62.5	Low	207 Å²	207	139.9 Å²	139.9	78%	0.784	74%	0.744	S	S	*	*			trans	-49.4	126.7	149.5	-84.9	63.3	0	0	0	108.3	H23 A28	H23-W26 AromaticContact CD2-NE1 3.74Å; H23-W26 PolarHBondContact NE2-NE1 2.96Å; H23-W26 AromaticContact NE2-NE1 2.98Å; H23-W26 AromaticContact NE2-CD1 3.52Å; H23-W26 AromaticContact CE1-NE1 3.74Å; H23-W26 AromaticContact CE1-CD1 3.88Å; W26-A28 PolarHBondContact O-N 2.98Å
27	H	63.7	Low	62	Low	148 Å²	148	141.6 Å²	141.6	69%	0.685	75%	0.754	S	S	*	*			trans	-61.5	103.3	166.6	-78.5	-103	0	0	0	107	K25 D29	K25-H27 PolarHBondContact O-N 2.99Å; H27-D29 PolarHBondContact O-N 2.98Å
28	A	64.6	Low	61.5	Low	93 Å²	93	141.8 Å²	141.8	77%	0.769	76%	0.76	S	S	*	*			trans	-73.5	78.4	155.9	0	0	0	0	0	105.9	W26 S30	W26-A28 PolarHBondContact O-N 2.98Å; A28-S30 PolarHBondContact O-N 3.31Å
29	D	67.4	Low	61	Low	136 Å²	136	139.3 Å²	139.3	73%	0.727	76%	0.758	S	S	*	*			trans	-66.2	93.4	161.2	-70.2	-51.8	0	0	0	106.5	H27	H27-D29 PolarHBondContact O-N 2.98Å
30	S	62.8	Low	61.2	Low	99 Å²	99	138.1 Å²	138.1	69%	0.692	76%	0.76	S	S	*	*			trans	-155.7	51.4	167.7	-67.1	0	0	0	0	110.1	A28	A28-S30 PolarHBondContact O-N 3.31Å
31	D	62.6	Low	61.3	Low	164 Å²	164	146.1 Å²	146.1	88%	0.877	79%	0.794	S	S	*	*			trans	-108.2	61.5	156.3	-101.1	-64.7	0	0	0	108.2	G33	D31-G33 VanDerWaalsContact C-N 3.27Å
32	T	65.6	Low	62.1	Low	145 Å²	145	138.8 Å²	138.8	89%	0.89	79%	0.786	S	S	*	*			trans	-97.7	59.3	156.3	47.5	0	0	0	0	108.2
33	G	68.3	Low	62.6	Low	60 Å²	60	142.3 Å²	142.3	62%	0.619	78%	0.784	S	S	*	*			trans	-119.3	78.3	179.2	0	0	0	0	0	112.4	D31	D31-G33 VanDerWaalsContact C-N 3.27Å
34	H	45.4	Very low	62.7	Low	265 Å²	265	142.4 Å²	142.4	100%	1.227	80%	0.796	S	S	*	*			trans	64.8	0	162.2	-164.1	74.8	0	0	0	119.1

Retrieved 34 of 34 residues in 288.3 ms (Link to these results)

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