A0A087WZE7_HUMAN Loading...

Zinc finger MYND-type containing 12

AlphaFold DB , UniProt , Accession A0A087WZE7, Species HUMAN (Homo sapiens, Human), Gene ZMYND12, Length 44 aa.

>A0A087WZE7_HUMAN|A0A087WZE7|ZMYND12
MNVIYPLAVPKGRRLCCEVCEAPAERVCAACTVTYYWSGPNRSG
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M41.1Very low55.1Low230 Ų230138.3 Ų138.3100%1.13373%0.732SS**  098.90-160.678.4155.900107.4V3M1-V3 HydrophobicContact CG-CG2 4.1Å; M1-V3 PolarHBondContact O-N 3.09Å
2N56.6Low55.1Low159 Ų159133.8 Ų133.885%0.8574%0.744SS**  trans-94.291.6-179.4-136-44.2000107.5I4N2-I4 PolarHBondContact O-N 3.28Å; N2-I4 VanDerWaalsContact O-N 3.09Å
3V57.7Low55.5Low93 Ų93138.6 Ų138.656%0.56474%0.744SS**  trans-77.595-178.8-177.20000107.4M1 Y5M1-V3 HydrophobicContact CG-CG2 4.1Å; M1-V3 PolarHBondContact O-N 3.09Å; V3-Y5 HydrophobicContact CG1-CD2 3.93Å; V3-Y5 HydrophobicContact CG1-CE2 3.68Å; V3-Y5 PolarHBondContact O-N 3.42Å
4I64.3Low56Low139 Ų139144.9 Ų144.971%0.71375%0.752SS**  trans-78.2108.7166.2-58-174000106N2 P6N2-I4 PolarHBondContact O-N 3.28Å; N2-I4 VanDerWaalsContact O-N 3.09Å; I4-P6 WeakPolarHBondContact O-CD 3.18Å
5Y54.1Low56.9Low200 Ų200139.8 Ų139.878%0.78473%0.726SS**  trans-70.5108.7165.7-81.9-88.8000107V3 L7V3-Y5 HydrophobicContact CG1-CD2 3.93Å; V3-Y5 HydrophobicContact CG1-CE2 3.68Å; V3-Y5 PolarHBondContact O-N 3.42Å; Y5-L7 PolarHBondContact O-N 3.23Å
6P55Low58Low107 Ų107134.7 Ų134.770%0.69571%0.705SS**  trans-68108.8-179.227.7-29.3000106.3I4 A8I4-P6 WeakPolarHBondContact O-CD 3.18Å; P6-A8 WeakPolarHBondContact O-CA 3.45Å; P6-A8 PolarHBondContact O-N 3.34Å
7L57.3Low58.9Low138 Ų138127.3 Ų127.372%0.72367%0.667SS**  trans9.771.2161-70.6160.5000111.8Y5 V9 V33Y5-L7 PolarHBondContact O-N 3.23Å; L7-V9 PolarHBondContact O-N 2.88Å; L7-V33 HydrophobicContact CD2-CG1 4.39Å
8A55.8Low59.6Low84 Ų84127.3 Ų127.369%0.69466%0.663SS**  trans-71.195.6-178.500000103.6P6 P10P6-A8 WeakPolarHBondContact O-CA 3.45Å; P6-A8 PolarHBondContact O-N 3.34Å; A8-P10 WeakPolarHBondContact O-CD 3.39Å
9V56.2Low60.2Low79 Ų79126.9 Ų126.948%0.47967%0.666SS.*  trans-52.3112.7162.8-175.50000103.3L7 K11 L15L7-V9 PolarHBondContact O-N 2.88Å; V9-K11 PolarHBondContact O-N 3.29Å; V9-L15 HydrophobicContact CG1-CD2 4.27Å
10P55Low61.2Low71 Ų71123.6 Ų123.646%0.46165%0.654SS.*  trans-59.9112.7-171.76.7-9.2000106.7A8 G12 R13A8-P10 WeakPolarHBondContact O-CD 3.39Å; P10-G12 PolarHBondContact O-N 2.84Å; P10-R13 HydrophobicContact CB-CB 4.09Å; P10-R13 HydrophobicContact CG-CB 3.78Å; P10-R13 PolarHBondContact O-N 2.82Å
11K53.3Low61.9Low221 Ų221125.4 Ų125.496%0.96166%0.658SS**THydrogen-bonded Turntrans-55.5108.6176.8-80.7-174.6175.51800106.6V9V9-K11 PolarHBondContact O-N 3.29Å
12G55.1Low63.7Low85 Ų85115.4 Ų115.488%0.87661%0.612SS**THydrogen-bonded Turntrans109.4-2.6179.500000116.6P10P10-G12 PolarHBondContact O-N 2.84Å
13R60.7Low64.7Low196 Ų196112.2 Ų112.274%0.7460%0.6SS**  trans-86.2119171.4-153.9168.5-173.6171.50.3109.2P10 L15P10-R13 HydrophobicContact CB-CB 4.09Å; P10-R13 HydrophobicContact CG-CB 3.78Å; P10-R13 PolarHBondContact O-N 2.82Å; R13-L15 PolarHBondContact O-N 2.94Å
14R62.5Low65.7Low227 Ų227108.7 Ų108.786%0.85758%0.581SS**  trans-56.5123.6170.5-77.6-179.9175.3171.6-1.8107.8C16R14-C16 PolarHBondContact O-N 2.68Å
15L69.4Low66.3Low68 Ų68108.8 Ų108.836%0.35658%0.578SS.*  trans-70.4114.2172.9-63.4172.3000106.7V9 R13 A24 Y35V9-L15 HydrophobicContact CG1-CD2 4.27Å; R13-L15 PolarHBondContact O-N 2.94Å; L15-A24 HydrophobicContact CB-CB 4.23Å; L15-A24 PolarHBondContact O-N 3.44Å; L15-Y35 HydrophobicContact CB-CD1 4.03Å; L15-Y35 HydrophobicContact CB-CE1 4.47Å; L15-Y35 HydrophobicContact CB-CG 4.39Å; L15-Y35 HydrophobicContact CD1-CD1 3.78Å; L15-Y35 HydrophobicContact CD1-CE1 3.49Å; L15-Y35 VanDerWaalsContact CD1-CE1 3.49Å; L15-Y35 HydrophobicContact CD2-CD1 3.76Å; L15-Y35 HydrophobicContact CD2-CD2 4.1Å; L15-Y35 HydrophobicContact CD2-CE1 3.48Å; L15-Y35 VanDerWaalsContact CD2-CE1 3.48Å; L15-Y35 HydrophobicContact CD2-CE2 3.85Å; L15-Y35 HydrophobicContact CD2-CG 4.07Å; L15-Y35 HydrophobicContact CG-CD1 4.06Å; L15-Y35 HydrophobicContact CG-CE1 3.98Å
16C74.1Confident67.1Low58 Ų58106.1 Ų106.139%0.39257%0.567SS.*BIsolated β-bridgetrans-115.3146.4-178.9-71.20000109.3R14 E18 E21 A22R14-C16 PolarHBondContact O-N 2.68Å; C16-E18 PolarHBondContact O-N 2.83Å; C16-E21 WeakPolarHBondContact CB-O 3.43Å; C16-E21 PolarHBondContact SG-O 3.45Å; C16-A22 CarbonylContact C-O 3.54Å; C16-A22 WeakPolarHBondContact CA-O 3.4Å
17C73.8Confident68.2Low9 Ų9104.5 Ų104.56%0.06156%0.555CS.*  trans-61.6129.6170.9-174.40000109.7V19 C20 E21 A22 Y35 W37C17-V19 PolarHBondContact O-N 3.13Å; C17-V19 VanDerWaalsContact O-N 3.12Å; C17-C20 VanDerWaalsContact CB-SG 3.53Å; C17-C20 VanDerWaalsContact SG-SG 3.61Å; C17-E21 VanDerWaalsContact O-CA 3.24Å; C17-E21 WeakPolarHBondContact O-CA 3.49Å; C17-E21 PolarHBondContact O-N 2.85Å; C17-A22 PolarHBondContact N-O 3.37Å; C17-Y35 WeakPolarHBondContact CA-O 3.42Å; C17-W37 HydrophobicContact CB-CB 3.65Å; C17-W37 PolarHBondContact SG-N 3.41Å
18E70.4Confident69.1Low127 Ų12799.1 Ų99.159%0.59353%0.529SS*.THydrogen-bonded Turntrans-64-17.8178.868.8-172.5174.300113.5C16 T34C16-E18 PolarHBondContact O-N 2.83Å; E18-T34 HydrophobicContact CG-CG2 4.34Å; E18-T34 WeakPolarHBondContact OE1-CG2 3.17Å; E18-T34 WeakPolarHBondContact OE2-CG2 3.4Å
19V72.3Confident70Confident120 Ų12099.9 Ų99.973%0.72754%0.535SS*.THydrogen-bonded Turntrans-92.4-42.7-177.3-176.70000112.5C17C17-V19 PolarHBondContact O-N 3.13Å; C17-V19 VanDerWaalsContact O-N 3.12Å
20C78.9Confident70.9Confident61 Ų61100.8 Ų100.841%0.41255%0.55SS.*THydrogen-bonded Turntrans-127.52.9-169.7650000114.3C17 A22C17-C20 VanDerWaalsContact CB-SG 3.53Å; C17-C20 VanDerWaalsContact SG-SG 3.61Å; C20-A22 PolarHBondContact O-N 2.77Å
21E77.1Confident71.8Confident161 Ų16199.9 Ų99.975%0.75255%0.545SS*.  trans590.9-179.6-59.8-177-133.700115.9C16 C17C16-E21 WeakPolarHBondContact CB-O 3.43Å; C16-E21 PolarHBondContact SG-O 3.45Å; C17-E21 VanDerWaalsContact O-CA 3.24Å; C17-E21 WeakPolarHBondContact O-CA 3.49Å; C17-E21 PolarHBondContact O-N 2.85Å
22A79.1Confident72.7Confident20 Ų2093.4 Ų93.417%0.16552%0.524CS..SBendtrans-64.8154.8174.900000111.5C16 C17 C20 A24 W37C16-A22 CarbonylContact C-O 3.54Å; C16-A22 WeakPolarHBondContact CA-O 3.4Å; C17-A22 PolarHBondContact N-O 3.37Å; C20-A22 PolarHBondContact O-N 2.77Å; A22-A24 PolarHBondContact O-N 3.49Å; A22-A24 VanDerWaalsContact O-N 3.12Å; A22-W37 HydrophobicContact CB-CB 4.06Å; A22-W37 HydrophobicContact CB-CD2 3.66Å; A22-W37 HydrophobicContact CB-CE3 4.31Å; A22-W37 HydrophobicContact CB-CG 3.58Å
23P76.8Confident73.5Confident93 Ų9393.4 Ų93.460%0.60451%0.507SS*.BIsolated β-bridgetrans-54.1119.7178.9-24.533.9000111.2
24A78.3Confident74Confident19 Ų1985.1 Ų85.116%0.15748%0.478CS..PPolyproline II helixtrans-76.9130.6-179.300000110.8L15 A22 Y36L15-A24 HydrophobicContact CB-CB 4.23Å; L15-A24 PolarHBondContact O-N 3.44Å; A22-A24 PolarHBondContact O-N 3.49Å; A22-A24 VanDerWaalsContact O-N 3.12Å; A24-Y36 CarbonylContact C-O 3.59Å; A24-Y36 VanDerWaalsContact CA-O 3.29Å; A24-Y36 WeakPolarHBondContact CA-O 3.46Å; A24-Y36 WeakPolarHBondContact CB-O 3.24Å
25E76.8Confident74.6Confident141 Ų14176.9 Ų76.966%0.65945%0.448SS*.  trans-109.9-6.2177.5-64.7180-176.300111.9Y36 S38E25-Y36 PolarHBondContact N-O 2.88Å; E25-S38 WeakPolarHBondContact OE2-CB 3.4Å; E25-S38 PolarHBondContact OE2-OG 2.54Å
26R70.2Confident74.6Confident144 Ų14476.9 Ų76.954%0.54344%0.443SS..EExtended strand (participates in β ladder)trans-134.9149.2-176.3-65.3-176.2174.7176.6-1.5111.3Y35 Y36R26-Y35 WeakPolarHBondContact O-CA 3.47Å; R26-Y36 PolarHBondContact N-O 2.93Å; R26-Y36 VanDerWaalsContact N-O 3.13Å; R26-Y36 PolarHBondContact O-N 3.05Å
27V80.1Confident74.9Confident73 Ų7378 Ų7844%0.44244%0.44SS..EExtended strand (participates in β ladder)trans-114.4141174.2173.80000109A29 Y35V27-A29 PolarHBondContact O-N 3.12Å; V27-Y35 HydrophobicContact CG2-CD1 3.53Å; V27-Y35 HydrophobicContact CG2-CE1 3.42Å; V27-Y35 VanDerWaalsContact CG2-CE1 3.42Å
28C74.5Confident74.6Confident25 Ų2579.6 Ų79.617%0.16945%0.45CS..  trans-61.5118.2171.7-175.90000110.2A30 C31 T32 T34 Y36C28-A30 PolarHBondContact O-N 2.82Å; C28-C31 WeakPolarHBondContact CB-SG 3.09Å; C28-T32 WeakPolarHBondContact O-CA 3.13Å; C28-T32 PolarHBondContact O-N 3.2Å; C28-T34 PolarHBondContact N-O 2.82Å; C28-Y36 HydrophobicContact CB-CD2 4.48Å; C28-Y36 HydrophobicContact CB-CE2 3.65Å
29A76.3Confident74.5Confident100 Ų10074.2 Ų74.283%0.82643%0.429SS*.THydrogen-bonded Turntrans-66.8-24.1-179.200000113.3V27V27-A29 PolarHBondContact O-N 3.12Å
30A73.7Confident74Confident97 Ų9774.4 Ų74.480%0.80243%0.433SS*.THydrogen-bonded Turntrans-81.4-48.2-177.400000112.9C28C28-A30 PolarHBondContact O-N 2.82Å
31C75.6Confident73.1Confident53 Ų5378.2 Ų78.236%0.35845%0.449SS..THydrogen-bonded Turntrans-103-16.7-176690000114C28 V33 T34C28-C31 WeakPolarHBondContact CB-SG 3.09Å; C31-V33 HydrophobicContact CB-CG2 4.02Å; C31-V33 PolarHBondContact O-N 2.98Å; C31-T34 PolarHBondContact SG-OG1 3.26Å
32T71.9Confident72.1Confident84 Ų8477.1 Ų77.152%0.51544%0.438SS..SBendtrans55.1-1.5-178.668.50000117.1C28C28-T32 WeakPolarHBondContact O-CA 3.13Å; C28-T32 PolarHBondContact O-N 3.2Å
33V70.7Confident70.7Confident85 Ų8581.6 Ų81.652%0.51547%0.468SS..SBendtrans-103.4-15.6179.7-63.70000113.6L7 C31 Y35L7-V33 HydrophobicContact CD2-CG1 4.39Å; C31-V33 HydrophobicContact CB-CG2 4.02Å; C31-V33 PolarHBondContact O-N 2.98Å; V33-Y35 WeakPolarHBondContact O-CD2 3.42Å; V33-Y35 WeakPolarHBondContact O-CE2 3.29Å
34T72.3Confident69.4Low23 Ų2384.5 Ų84.514%0.14152%0.515CS..  trans-96.3129.7179.5-58.40000111E18 C28 C31 Y36E18-T34 HydrophobicContact CG-CG2 4.34Å; E18-T34 WeakPolarHBondContact OE1-CG2 3.17Å; E18-T34 WeakPolarHBondContact OE2-CG2 3.4Å; C28-T34 PolarHBondContact N-O 2.82Å; C31-T34 PolarHBondContact SG-OG1 3.26Å; T34-Y36 HydrophobicContact CG2-CD1 4.2Å; T34-Y36 HydrophobicContact CG2-CE1 3.51Å; T34-Y36 HydrophobicContact CG2-CE2 3.94Å; T34-Y36 WeakPolarHBondContact CG2-OH 3.35Å
35Y73.7Confident68.9Low54 Ų5487.8 Ų87.821%0.21253%0.533CS..EExtended strand (participates in β ladder)trans-110.7135.9-178.7-65.3-92.3000109.9L15 C17 R26 V27 V33L15-Y35 HydrophobicContact CB-CD1 4.03Å; L15-Y35 HydrophobicContact CB-CE1 4.47Å; L15-Y35 HydrophobicContact CB-CG 4.39Å; L15-Y35 HydrophobicContact CD1-CD1 3.78Å; L15-Y35 HydrophobicContact CD1-CE1 3.49Å; L15-Y35 VanDerWaalsContact CD1-CE1 3.49Å; L15-Y35 HydrophobicContact CD2-CD1 3.76Å; L15-Y35 HydrophobicContact CD2-CD2 4.1Å; L15-Y35 HydrophobicContact CD2-CE1 3.48Å; L15-Y35 VanDerWaalsContact CD2-CE1 3.48Å; L15-Y35 HydrophobicContact CD2-CE2 3.85Å; L15-Y35 HydrophobicContact CD2-CG 4.07Å; L15-Y35 HydrophobicContact CG-CD1 4.06Å; L15-Y35 HydrophobicContact CG-CE1 3.98Å; C17-Y35 WeakPolarHBondContact CA-O 3.42Å; R26-Y35 WeakPolarHBondContact O-CA 3.47Å; V27-Y35 HydrophobicContact CG2-CD1 3.53Å; V27-Y35 HydrophobicContact CG2-CE1 3.42Å; V27-Y35 VanDerWaalsContact CG2-CE1 3.42Å; V33-Y35 WeakPolarHBondContact O-CD2 3.42Å; V33-Y35 WeakPolarHBondContact O-CE2 3.29Å
36Y70.3Confident68.5Low67 Ų6784.9 Ų84.926%0.26353%0.526SS..EExtended strand (participates in β ladder)trans-126.5147.5-176.8-58.5-68.2000112.6A24 E25 R26 C28 T34A24-Y36 CarbonylContact C-O 3.59Å; A24-Y36 VanDerWaalsContact CA-O 3.29Å; A24-Y36 WeakPolarHBondContact CA-O 3.46Å; A24-Y36 WeakPolarHBondContact CB-O 3.24Å; E25-Y36 PolarHBondContact N-O 2.88Å; R26-Y36 PolarHBondContact N-O 2.93Å; R26-Y36 VanDerWaalsContact N-O 3.13Å; R26-Y36 PolarHBondContact O-N 3.05Å; C28-Y36 HydrophobicContact CB-CD2 4.48Å; C28-Y36 HydrophobicContact CB-CE2 3.65Å; T34-Y36 HydrophobicContact CG2-CD1 4.2Å; T34-Y36 HydrophobicContact CG2-CE1 3.51Å; T34-Y36 HydrophobicContact CG2-CE2 3.94Å; T34-Y36 WeakPolarHBondContact CG2-OH 3.35Å
37W80.8Confident68.4Low83 Ų8381.7 Ų81.731%0.31453%0.525SS..  trans-80.4150.7165.8-176.354.6000111.2C17 A22 G39 R42C17-W37 HydrophobicContact CB-CB 3.65Å; C17-W37 PolarHBondContact SG-N 3.41Å; A22-W37 HydrophobicContact CB-CB 4.06Å; A22-W37 HydrophobicContact CB-CD2 3.66Å; A22-W37 HydrophobicContact CB-CE3 4.31Å; A22-W37 HydrophobicContact CB-CG 3.58Å; W37-G39 VanDerWaalsContact CD2-N 3.35Å; W37-G39 VanDerWaalsContact CE2-CA 3.48Å; W37-R42 PolarHBondContact O-NE 3.12Å; W37-R42 PolarHBondContact O-NH2 3.23Å
38S67.9Low67.8Low41 Ų4182.2 Ų82.229%0.28753%0.53SS..  trans-101.31.5-178.256.40000113.3E25E25-S38 WeakPolarHBondContact OE2-CB 3.4Å; E25-S38 PolarHBondContact OE2-OG 2.54Å
39G67.5Low67.3Low14 Ų1485.8 Ų85.814%0.14455%0.552CS.*SBendtrans-66.4176-173.600000115.8W37 N41W37-G39 VanDerWaalsContact CD2-N 3.35Å; W37-G39 VanDerWaalsContact CE2-CA 3.48Å; G39-N41 PolarHBondContact O-N 2.85Å
40P61.9Low66.7Low124 Ų12484.8 Ų84.881%0.80553%0.534SS*.SBendtrans-64.3-10.4-162.123.6-34.8000115.9R42P40-R42 PolarHBondContact O-N 2.85Å
41N59.7Low66.2Low141 Ų14183.9 Ų83.975%0.75452%0.515SS*.  trans-101.960179.5-85.91.2000112.5G39G39-N41 PolarHBondContact O-N 2.85Å
42R56.1Low65.5Low138 Ų13886.3 Ų86.352%0.52153%0.527SS..  trans-106.678.2153.8-78.6-165.8-173.5-157.71.3109W37 P40W37-R42 PolarHBondContact O-NE 3.12Å; W37-R42 PolarHBondContact O-NH2 3.23Å; P40-R42 PolarHBondContact O-N 2.85Å
43S49.4Very low65Low115 Ų11586.5 Ų86.580%0.80453%0.528SS*.  trans-83.8108.3160.548.50000108.4
44G49.7Very low64.5Low153 Ų15386.6 Ų86.6100%1.57753%0.529SS*.  trans90.40164.900000115.1

Retrieved 44 of 44 residues in 9 ms (Link to these results)