A0A087X004_HUMAN Loading...

glutaminase

AlphaFold DB , UniProt , Accession A0A087X004, Species HUMAN (Homo sapiens, Human), Gene GLS2, Length 337 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M90.4Very high95.6Very high81 Ų8143.3 Ų43.340%0.39928%0.277SS..  0-3.80-60.6-50.4176.100114.6L127 M128 C131 K149M1-L127 HydrophobicContact CE-CB 3.73Å; M1-L127 HydrophobicContact CG-CB 4.41Å; M1-M128 HydrophobicContact CE-CB 4.44Å; M1-M128 HydrophobicContact CE-CG 3.6Å; M1-C131 HydrophobicContact CB-CB 3.77Å; M1-C131 WeakPolarHBondContact CB-O 3.12Å; M1-C131 HydrophobicContact CG-CB 3.85Å; M1-K149 HydrophobicContact SD-CD 3.94Å
2V95.3Very high95.5Very high101 Ų10147.8 Ų47.861%0.61230%0.296SS*.  trans-100.4157.9173.2-61.80000111.1A4 G5 A6V2-A4 VanDerWaalsContact C-N 3.35Å; V2-A4 PolarHBondContact O-N 3.32Å; V2-G5 PolarHBondContact O-N 3.14Å; V2-G5 VanDerWaalsContact O-N 3.1Å; V2-A6 PolarHBondContact O-N 2.89Å
3N95.3Very high95.4Very high63 Ų6346.9 Ų46.934%0.33729%0.288SS..Hα-helixtrans-52.6-47.1-176.2-62.520.7000113G5 A6 I7 N56 Y82N3-G5 VanDerWaalsContact C-N 3.32Å; N3-G5 PolarHBondContact O-N 3.17Å; N3-A6 PolarHBondContact O-N 3.14Å; N3-A6 VanDerWaalsContact O-N 3.11Å; N3-I7 WeakPolarHBondContact O-CG1 3.28Å; N3-I7 PolarHBondContact O-N 3.29Å; N3-N56 PolarHBondContact ND2-OD1 3.1Å; N3-Y82 PolarHBondContact ND2-OH 3.07Å
4A96.7Very high95Very high34 Ų3450.9 Ų50.928%0.28130%0.299SS..Hα-helixtrans-57.3-44.1179.900000112.5V2 V8 I59V2-A4 VanDerWaalsContact C-N 3.35Å; V2-A4 PolarHBondContact O-N 3.32Å; A4-V8 WeakPolarHBondContact O-CG2 3.46Å; A4-V8 PolarHBondContact O-N 3.11Å; A4-I59 HydrophobicContact CB-CG2 3.69Å
5G96.8Very high94.3Very high31 Ų3154.3 Ų54.332%0.3231%0.313SS..Hα-helixtrans-68.1-39.3176.600000112.2V2 N3 V8 V9V2-G5 PolarHBondContact O-N 3.14Å; V2-G5 VanDerWaalsContact O-N 3.1Å; N3-G5 VanDerWaalsContact C-N 3.32Å; N3-G5 PolarHBondContact O-N 3.17Å; G5-V8 PolarHBondContact O-N 3.49Å; G5-V9 VanDerWaalsContact O-CG2 3.3Å; G5-V9 WeakPolarHBondContact O-CG2 2.94Å; G5-V9 PolarHBondContact O-N 3.33Å
6A96.9Very high93.7Very high37 Ų3761.1 Ų61.131%0.30635%0.348SS..Hα-helixtrans-63-41.6176.700000112V2 N3 V8 V9 S10 Y82V2-A6 PolarHBondContact O-N 2.89Å; N3-A6 PolarHBondContact O-N 3.14Å; N3-A6 VanDerWaalsContact O-N 3.11Å; A6-V8 VanDerWaalsContact C-N 3.35Å; A6-V8 PolarHBondContact O-N 3.33Å; A6-V9 PolarHBondContact O-N 3.09Å; A6-S10 PolarHBondContact O-N 3.31Å; A6-S10 PolarHBondContact O-OG 3.07Å; A6-S10 VanDerWaalsContact O-OG 3.13Å; A6-Y82 HydrophobicContact CB-CD2 4.08Å; A6-Y82 HydrophobicContact CB-CE2 3.75Å
7I96.8Very high93.2Very high0 Ų060 Ų600%034%0.344CS..Hα-helixtrans-60.9-43.4175.4-67.9163.4000111N3 S10 S11 N56 I59 L63 F69 L79 Y82N3-I7 WeakPolarHBondContact O-CG1 3.28Å; N3-I7 PolarHBondContact O-N 3.29Å; I7-S10 PolarHBondContact O-N 3.37Å; I7-S11 PolarHBondContact O-N 3.29Å; I7-N56 HydrophobicContact CD1-CB 4.26Å; I7-I59 HydrophobicContact CD1-CB 4.5Å; I7-I59 HydrophobicContact CD1-CG2 4.08Å; I7-L63 HydrophobicContact CG2-CD1 4.37Å; I7-F69 HydrophobicContact CG2-CE1 4.06Å; I7-F69 HydrophobicContact CG2-CZ 4.02Å; I7-L79 HydrophobicContact CD1-CD1 3.9Å; I7-L79 HydrophobicContact CG1-CD1 4.25Å; I7-L79 HydrophobicContact CG2-CD1 4.25Å; I7-Y82 HydrophobicContact CG1-CD1 4.14Å; I7-Y82 HydrophobicContact CG1-CD2 3.89Å; I7-Y82 HydrophobicContact CG1-CE1 4.44Å; I7-Y82 HydrophobicContact CG1-CE2 4.2Å; I7-Y82 HydrophobicContact CG1-CG 3.86Å
8V97.1Very high92.8Very high35 Ų3561.2 Ų61.221%0.21235%0.349CS..Hα-helixtrans-64.1-43.4175176.50000110.7A4 G5 A6 S10 S11 L63 F69A4-V8 WeakPolarHBondContact O-CG2 3.46Å; A4-V8 PolarHBondContact O-N 3.11Å; G5-V8 PolarHBondContact O-N 3.49Å; A6-V8 VanDerWaalsContact C-N 3.35Å; A6-V8 PolarHBondContact O-N 3.33Å; V8-S10 VanDerWaalsContact C-N 3.34Å; V8-S10 PolarHBondContact O-N 3.22Å; V8-S11 WeakPolarHBondContact O-CB 3.34Å; V8-S11 PolarHBondContact O-N 3.46Å; V8-S11 VanDerWaalsContact O-N 3.08Å; V8-S11 PolarHBondContact O-OG 3.43Å; V8-L63 HydrophobicContact CG2-CD1 3.86Å; V8-L63 HydrophobicContact CG2-CD2 4.28Å; V8-F69 HydrophobicContact CG2-CE1 4.41Å
9V96.6Very high92.3Very high85 Ų8562.6 Ų62.652%0.51535%0.351SS..Hα-helixtrans-60.5-42.1177.3170.30000111.5G5 A6 S11 L12G5-V9 VanDerWaalsContact O-CG2 3.3Å; G5-V9 WeakPolarHBondContact O-CG2 2.94Å; G5-V9 PolarHBondContact O-N 3.33Å; A6-V9 PolarHBondContact O-N 3.09Å; V9-S11 PolarHBondContact O-N 2.86Å; V9-L12 WeakPolarHBondContact O-CB 3.31Å; V9-L12 PolarHBondContact O-N 3.09Å
10S94.8Very high92.2Very high8 Ų862.5 Ų62.56%0.05636%0.358CS..Hα-helixtrans-57.5-32.1175.4-62.20000112.7A6 I7 V8 L12 I13A6-S10 PolarHBondContact O-N 3.31Å; A6-S10 PolarHBondContact O-OG 3.07Å; A6-S10 VanDerWaalsContact O-OG 3.13Å; I7-S10 PolarHBondContact O-N 3.37Å; V8-S10 VanDerWaalsContact C-N 3.34Å; V8-S10 PolarHBondContact O-N 3.22Å; S10-L12 VanDerWaalsContact C-N 3.26Å; S10-L12 PolarHBondContact O-N 3.36Å; S10-I13 PolarHBondContact O-N 3.32Å
11S94.5Very high92.1Very high1 Ų164 Ų641%0.00736%0.362CS..Hα-helixtrans-69.8-21.8177.2830000113.9I7 V8 V9 P70I7-S11 PolarHBondContact O-N 3.29Å; V8-S11 WeakPolarHBondContact O-CB 3.34Å; V8-S11 PolarHBondContact O-N 3.46Å; V8-S11 VanDerWaalsContact O-N 3.08Å; V8-S11 PolarHBondContact O-OG 3.43Å; V9-S11 PolarHBondContact O-N 2.86Å; S11-P70 WeakPolarHBondContact OG-CD 3.45Å
12L95.1Very high92.3Very high97 Ų9761.3 Ų61.351%0.50835%0.348SS..Hα-helixtrans-86.5-17.7-178.2-56176.9000112.7V9 S10 K14 P70V9-L12 WeakPolarHBondContact O-CB 3.31Å; V9-L12 PolarHBondContact O-N 3.09Å; S10-L12 VanDerWaalsContact C-N 3.26Å; S10-L12 PolarHBondContact O-N 3.36Å; L12-K14 PolarHBondContact O-N 3.48Å; L12-P70 HydrophobicContact CD2-CG 3.48Å; L12-P70 VanDerWaalsContact CD2-CG 3.48Å
13I93.9Very high92.2Very high37 Ų3757.6 Ų57.619%0.1932%0.324CS..THydrogen-bonded Turntrans-72.4121.2-176.8-58.9174.9000109.2S10 M15 K22 F25 V26 L85S10-I13 PolarHBondContact O-N 3.32Å; I13-M15 PolarHBondContact O-N 3.02Å; I13-K22 PolarHBondContact O-NZ 3.42Å; I13-K22 VanDerWaalsContact O-NZ 3.11Å; I13-F25 HydrophobicContact CG2-CD1 4.04Å; I13-F25 HydrophobicContact CG2-CE1 4.33Å; I13-V26 HydrophobicContact CD1-CG2 3.98Å; I13-V26 HydrophobicContact CG2-CG2 3.83Å; I13-L85 HydrophobicContact CD1-CD1 4.35Å
14K89.6Confident92.1Very high102 Ų10259.2 Ų59.244%0.44333%0.332SS..THydrogen-bonded Turntrans39.667.4173.9-79.9-74.2-171.31730112.1L12 D16 C17 K22 F25L12-K14 PolarHBondContact O-N 3.48Å; K14-D16 PolarHBondContact O-N 3.11Å; K14-D16 VanDerWaalsContact O-N 3.14Å; K14-C17 HydrophobicContact CB-CB 4.14Å; K14-C17 PolarHBondContact O-N 2.73Å; K14-C17 VanDerWaalsContact O-N 3.17Å; K14-K22 HydrophobicContact CB-CG 4.14Å; K14-K22 WeakPolarHBondContact O-CE 3.46Å; K14-K22 PolarHBondContact O-NZ 3Å; K14-F25 HydrophobicContact CD-CE2 4.46Å; K14-F25 HydrophobicContact CG-CD1 3.75Å; K14-F25 HydrophobicContact CG-CD2 4.13Å; K14-F25 HydrophobicContact CG-CE1 3.92Å; K14-F25 HydrophobicContact CG-CE2 4.28Å; K14-F25 HydrophobicContact CG-CG 3.86Å; K14-F25 HydrophobicContact CG-CZ 4.18Å
15M84.9Confident92.1Very high103 Ų10360.6 Ų60.651%0.50733%0.332SS..THydrogen-bonded Turntrans-55.3-34.4-170.9-66.7-174.7-63.200113.6I13 C17 P70I13-M15 PolarHBondContact O-N 3.02Å; M15-C17 PolarHBondContact O-N 3.39Å; M15-P70 HydrophobicContact SD-CB 4.05Å; M15-P70 HydrophobicContact SD-CG 4.15Å
16D84Confident92Very high163 Ų16360.1 Ų60.187%0.87232%0.323SS*.THydrogen-bonded Turntrans-85.9-1.5-174.5-50-52.9000114.7K14K14-D16 PolarHBondContact O-N 3.11Å; K14-D16 VanDerWaalsContact O-N 3.14Å
17C85.4Confident91.9Very high42 Ų4260 Ų6028%0.28432%0.317SS..SBendtrans-100159.6-175.8-70.20000112.8K14 M15 E21 K22K14-C17 HydrophobicContact CB-CB 4.14Å; K14-C17 PolarHBondContact O-N 2.73Å; K14-C17 VanDerWaalsContact O-N 3.17Å; M15-C17 PolarHBondContact O-N 3.39Å; C17-E21 WeakPolarHBondContact CA-OE2 3.33Å; C17-E21 HydrophobicContact CB-CB 3.91Å; C17-E21 VanDerWaalsContact CB-OE2 3.28Å; C17-E21 WeakPolarHBondContact CB-OE2 3.5Å; C17-K22 HydrophobicContact CB-CG 4.13Å; C17-K22 WeakPolarHBondContact O-CE 3.18Å
18N86.4Confident91.8Very high81 Ų8165.1 Ų65.143%0.43334%0.341SS..  trans-74.4170173.372.344.2000112A20 E21 K22N18-A20 VanDerWaalsContact C-N 3.34Å; N18-A20 PolarHBondContact O-N 2.6Å; N18-A20 PolarHBondContact OD1-N 3.08Å; N18-A20 VanDerWaalsContact OD1-N 3.09Å; N18-E21 VanDerWaalsContact CG-CD 3.46Å; N18-E21 PolarHBondContact N-OE2 3.21Å; N18-E21 VanDerWaalsContact N-OE2 3.14Å; N18-E21 PolarHBondContact ND2-OE1 3.42Å; N18-E21 PolarHBondContact O-N 3.32Å; N18-E21 WeakPolarHBondContact OD1-CB 3.04Å; N18-E21 WeakPolarHBondContact OD1-CG 3.37Å; N18-E21 PolarHBondContact OD1-N 3.19Å; N18-K22 VanDerWaalsContact O-CG 3.31Å; N18-K22 WeakPolarHBondContact O-CG 3.45Å; N18-K22 PolarHBondContact O-N 3.15Å; N18-K22 VanDerWaalsContact O-N 3.07Å
19K84Confident91.7Very high89 Ų8967.9 Ų67.939%0.38735%0.348SS..Hα-helixtrans-58.7-41.8-176.2-63.7-174.4-174.4-173.90113.1K22 F23 A77 D80K19-K22 PolarHBondContact O-N 2.96Å; K19-F23 PolarHBondContact O-N 3.48Å; K19-F23 VanDerWaalsContact O-N 3.17Å; K19-A77 HydrophobicContact CD-CB 4.41Å; K19-A77 VanDerWaalsContact CE-CB 3.47Å; K19-A77 HydrophobicContact CG-CB 4.4Å; K19-D80 IonicContact NZ-OD2 2.73Å; K19-D80 PolarHBondContact NZ-OD2 2.97Å
20A88.6Confident91.6Very high59 Ų5965.6 Ų65.649%0.48833%0.333SS..Hα-helixtrans-68.4-46.7-17800000111.2N18 K22 F23 D24N18-A20 VanDerWaalsContact C-N 3.34Å; N18-A20 PolarHBondContact O-N 2.6Å; N18-A20 PolarHBondContact OD1-N 3.08Å; N18-A20 VanDerWaalsContact OD1-N 3.09Å; A20-K22 VanDerWaalsContact C-N 3.27Å; A20-K22 PolarHBondContact O-N 3.45Å; A20-F23 WeakPolarHBondContact O-CB 3.47Å; A20-F23 PolarHBondContact O-N 2.97Å; A20-F23 VanDerWaalsContact O-N 3.07Å; A20-D24 PolarHBondContact O-N 3.03Å
21E91.9Very high91.7Very high94 Ų9467.4 Ų67.444%0.43934%0.342SS..Hα-helixtrans-59.2-36.9176.1-72.9166.5-170.900112.4C17 N18 F25C17-E21 WeakPolarHBondContact CA-OE2 3.33Å; C17-E21 HydrophobicContact CB-CB 3.91Å; C17-E21 VanDerWaalsContact CB-OE2 3.28Å; C17-E21 WeakPolarHBondContact CB-OE2 3.5Å; N18-E21 VanDerWaalsContact CG-CD 3.46Å; N18-E21 PolarHBondContact N-OE2 3.21Å; N18-E21 VanDerWaalsContact N-OE2 3.14Å; N18-E21 PolarHBondContact ND2-OE1 3.42Å; N18-E21 PolarHBondContact O-N 3.32Å; N18-E21 WeakPolarHBondContact OD1-CB 3.04Å; N18-E21 WeakPolarHBondContact OD1-CG 3.37Å; N18-E21 PolarHBondContact OD1-N 3.19Å; E21-F25 WeakPolarHBondContact O-CB 3.41Å; E21-F25 PolarHBondContact O-N 3.47Å
22K93.4Very high91.8Very high25 Ų2570.2 Ų70.211%0.10935%0.354CS..Hα-helixtrans-64.7-44.1174.6-70.4177.9-166.5-129.30111.7I13 K14 C17 N18 K19 A20 F25 V26 L81I13-K22 PolarHBondContact O-NZ 3.42Å; I13-K22 VanDerWaalsContact O-NZ 3.11Å; K14-K22 HydrophobicContact CB-CG 4.14Å; K14-K22 WeakPolarHBondContact O-CE 3.46Å; K14-K22 PolarHBondContact O-NZ 3Å; C17-K22 HydrophobicContact CB-CG 4.13Å; C17-K22 WeakPolarHBondContact O-CE 3.18Å; N18-K22 VanDerWaalsContact O-CG 3.31Å; N18-K22 WeakPolarHBondContact O-CG 3.45Å; N18-K22 PolarHBondContact O-N 3.15Å; N18-K22 VanDerWaalsContact O-N 3.07Å; K19-K22 PolarHBondContact O-N 2.96Å; A20-K22 VanDerWaalsContact C-N 3.27Å; A20-K22 PolarHBondContact O-N 3.45Å; K22-F25 PolarHBondContact O-N 3.49Å; K22-V26 WeakPolarHBondContact O-CG2 3.43Å; K22-V26 PolarHBondContact O-N 3.12Å; K22-V26 VanDerWaalsContact O-N 3.1Å; K22-L81 HydrophobicContact CB-CD1 4.26Å; K22-L81 HydrophobicContact CB-CD2 3.97Å; K22-L81 HydrophobicContact CD-CD2 4.06Å
23F93.6Very high91.9Very high23 Ų2366.5 Ų66.510%0.10133%0.334CS..Hα-helixtrans-64.2-47.8178.6-177.9-104.5000111.1K19 A20 F25 V26 L27 F41 L81 Q84 L85 V88K19-F23 PolarHBondContact O-N 3.48Å; K19-F23 VanDerWaalsContact O-N 3.17Å; A20-F23 WeakPolarHBondContact O-CB 3.47Å; A20-F23 PolarHBondContact O-N 2.97Å; A20-F23 VanDerWaalsContact O-N 3.07Å; F23-F25 VanDerWaalsContact C-N 3.31Å; F23-F25 PolarHBondContact O-N 3.4Å; F23-V26 PolarHBondContact O-N 2.72Å; F23-L27 HydrophobicContact CE1-CD2 4.19Å; F23-L27 WeakPolarHBondContact O-CB 3.49Å; F23-L27 PolarHBondContact O-N 3.44Å; F23-F41 HydrophobicContact CE2-CD2 4.04Å; F23-F41 HydrophobicContact CE2-CE2 4.22Å; F23-F41 HydrophobicContact CZ-CB 4.28Å; F23-F41 AromaticContact CZ-CD2 3.55Å; F23-F41 HydrophobicContact CZ-CD2 3.55Å; F23-F41 HydrophobicContact CZ-CE2 4.05Å; F23-F41 AromaticContact CZ-CG 3.96Å; F23-F41 HydrophobicContact CZ-CG 3.96Å; F23-L81 HydrophobicContact CB-CD1 4.22Å; F23-L81 HydrophobicContact CD2-CD1 4.5Å; F23-Q84 HydrophobicContact CD2-CB 3.84Å; F23-Q84 HydrophobicContact CE2-CB 3.92Å; F23-L85 HydrophobicContact CD2-CD2 4.21Å; F23-L85 HydrophobicContact CE2-CD2 4.39Å; F23-V88 HydrophobicContact CE2-CG2 4.17Å; F23-V88 HydrophobicContact CZ-CG2 4.46Å
24D94.1Very high92.1Very high98 Ų9864.7 Ų64.752%0.52433%0.325SS..Hα-helixtrans-60.2-41.7177.1-68.5-16.8000111.6A20 V26 L27 Q28A20-D24 PolarHBondContact O-N 3.03Å; D24-V26 PolarHBondContact O-N 3.41Å; D24-L27 PolarHBondContact O-N 3.27Å; D24-Q28 VanDerWaalsContact O-CB 3.3Å; D24-Q28 WeakPolarHBondContact O-CB 3.34Å; D24-Q28 PolarHBondContact O-N 2.97Å
25F94.9Very high92.4Very high62 Ų6260.4 Ų60.427%0.27231%0.31SS..Hα-helixtrans-58.9-46.7175.8175.1-97.2000112I13 K14 E21 K22 F23 Y29I13-F25 HydrophobicContact CG2-CD1 4.04Å; I13-F25 HydrophobicContact CG2-CE1 4.33Å; K14-F25 HydrophobicContact CD-CE2 4.46Å; K14-F25 HydrophobicContact CG-CD1 3.75Å; K14-F25 HydrophobicContact CG-CD2 4.13Å; K14-F25 HydrophobicContact CG-CE1 3.92Å; K14-F25 HydrophobicContact CG-CE2 4.28Å; K14-F25 HydrophobicContact CG-CG 3.86Å; K14-F25 HydrophobicContact CG-CZ 4.18Å; E21-F25 WeakPolarHBondContact O-CB 3.41Å; E21-F25 PolarHBondContact O-N 3.47Å; K22-F25 PolarHBondContact O-N 3.49Å; F23-F25 VanDerWaalsContact C-N 3.31Å; F23-F25 PolarHBondContact O-N 3.4Å; F25-Y29 HydrophobicContact CD2-CD2 4.45Å; F25-Y29 HydrophobicContact CD2-CE2 4.3Å; F25-Y29 HydrophobicContact CE1-CD2 4.13Å; F25-Y29 HydrophobicContact CE1-CE2 4.1Å; F25-Y29 HydrophobicContact CE2-CD2 4.01Å; F25-Y29 AromaticContact CE2-CE2 3.49Å; F25-Y29 HydrophobicContact CE2-CE2 3.49Å; F25-Y29 VanDerWaalsContact CE2-CE2 3.49Å; F25-Y29 AromaticContact CZ-CD2 3.83Å; F25-Y29 HydrophobicContact CZ-CD2 3.83Å; F25-Y29 AromaticContact CZ-CE2 3.36Å; F25-Y29 HydrophobicContact CZ-CE2 3.36Å; F25-Y29 WeakPolarHBondContact O-CD2 3.3Å; F25-Y29 PolarHBondContact O-N 2.91Å
26V95Very high92.9Very high21 Ų2161.4 Ų61.413%0.12732%0.317CS..Hα-helixtrans-67.7-45.5178.8177.70000110.5I13 K22 F23 D24 Q28 Y29 L30 L85I13-V26 HydrophobicContact CD1-CG2 3.98Å; I13-V26 HydrophobicContact CG2-CG2 3.83Å; K22-V26 WeakPolarHBondContact O-CG2 3.43Å; K22-V26 PolarHBondContact O-N 3.12Å; K22-V26 VanDerWaalsContact O-N 3.1Å; F23-V26 PolarHBondContact O-N 2.72Å; D24-V26 PolarHBondContact O-N 3.41Å; V26-Q28 VanDerWaalsContact C-N 3.26Å; V26-Q28 PolarHBondContact O-N 3.22Å; V26-Y29 WeakPolarHBondContact O-CB 3.41Å; V26-Y29 PolarHBondContact O-N 3.39Å; V26-L30 HydrophobicContact CG1-CD1 4.03Å; V26-L30 HydrophobicContact CG1-CG 4.18Å; V26-L30 WeakPolarHBondContact O-CG 3.39Å; V26-L30 PolarHBondContact O-N 2.92Å; V26-L85 HydrophobicContact CB-CD2 3.85Å; V26-L85 HydrophobicContact CG1-CD1 4.46Å; V26-L85 HydrophobicContact CG1-CD2 3.48Å; V26-L85 VanDerWaalsContact CG1-CD2 3.48Å; V26-L85 HydrophobicContact CG2-CD2 4.29Å
27L94.2Very high93.5Very high34 Ų3456.7 Ų56.718%0.17829%0.29CS..Hα-helixtrans-61.6-36.8-179.8-167.365.1000111.5F23 D24 L30 N31 M39 V88F23-L27 HydrophobicContact CE1-CD2 4.19Å; F23-L27 WeakPolarHBondContact O-CB 3.49Å; F23-L27 PolarHBondContact O-N 3.44Å; D24-L27 PolarHBondContact O-N 3.27Å; L27-L30 PolarHBondContact O-N 2.86Å; L27-N31 WeakPolarHBondContact O-CB 3.5Å; L27-N31 PolarHBondContact O-N 3.39Å; L27-N31 PolarHBondContact O-ND2 2.9Å; L27-N31 VanDerWaalsContact O-ND2 3.11Å; L27-M39 HydrophobicContact CD1-CB 4.24Å; L27-M39 HydrophobicContact CD1-CE 4.01Å; L27-V88 HydrophobicContact CD1-CG1 4.46Å
28Q94.8Very high94Very high109 Ų10960.5 Ų60.551%0.50930%0.299SS..Hα-helixtrans-61.2-43172.8-171.2-178.618.300111.9D24 V26 N31 K32D24-Q28 VanDerWaalsContact O-CB 3.3Å; D24-Q28 WeakPolarHBondContact O-CB 3.34Å; D24-Q28 PolarHBondContact O-N 2.97Å; V26-Q28 VanDerWaalsContact C-N 3.26Å; V26-Q28 PolarHBondContact O-N 3.22Å; Q28-N31 PolarHBondContact O-N 3.47Å; Q28-K32 WeakPolarHBondContact O-CG 3.39Å; Q28-K32 PolarHBondContact O-N 3.19Å
29Y94.9Very high94.4Very high92 Ų9257.9 Ų57.936%0.36129%0.285SS..Hα-helixtrans-65-42.8175.4-96.5-95.1000112.2F25 V26 K32 M33 V115 L116F25-Y29 HydrophobicContact CD2-CD2 4.45Å; F25-Y29 HydrophobicContact CD2-CE2 4.3Å; F25-Y29 HydrophobicContact CE1-CD2 4.13Å; F25-Y29 HydrophobicContact CE1-CE2 4.1Å; F25-Y29 HydrophobicContact CE2-CD2 4.01Å; F25-Y29 AromaticContact CE2-CE2 3.49Å; F25-Y29 HydrophobicContact CE2-CE2 3.49Å; F25-Y29 VanDerWaalsContact CE2-CE2 3.49Å; F25-Y29 AromaticContact CZ-CD2 3.83Å; F25-Y29 HydrophobicContact CZ-CD2 3.83Å; F25-Y29 AromaticContact CZ-CE2 3.36Å; F25-Y29 HydrophobicContact CZ-CE2 3.36Å; F25-Y29 WeakPolarHBondContact O-CD2 3.3Å; F25-Y29 PolarHBondContact O-N 2.91Å; V26-Y29 WeakPolarHBondContact O-CB 3.41Å; V26-Y29 PolarHBondContact O-N 3.39Å; Y29-K32 PolarHBondContact O-N 3.1Å; Y29-M33 WeakPolarHBondContact O-CG 3.48Å; Y29-M33 PolarHBondContact O-N 3.47Å; Y29-V115 HydrophobicContact CD1-CG1 3.97Å; Y29-V115 HydrophobicContact CE1-CG1 4.44Å; Y29-V115 WeakPolarHBondContact CE1-O 3.43Å; Y29-L116 HydrophobicContact CD1-CD2 4.28Å; Y29-L116 HydrophobicContact CE1-CD2 4.49Å
30L95.9Very high94.8Very high38 Ų3854.2 Ų54.220%0.19927%0.272CS..Hα-helixtrans-64.2-41.6177.3-61.4176.2000111.4V26 L27 K32 M33 A34 M39 V88 M98V26-L30 HydrophobicContact CG1-CD1 4.03Å; V26-L30 HydrophobicContact CG1-CG 4.18Å; V26-L30 WeakPolarHBondContact O-CG 3.39Å; V26-L30 PolarHBondContact O-N 2.92Å; L27-L30 PolarHBondContact O-N 2.86Å; L30-K32 VanDerWaalsContact C-N 3.35Å; L30-K32 PolarHBondContact O-N 2.89Å; L30-M33 WeakPolarHBondContact O-CB 3.35Å; L30-M33 PolarHBondContact O-N 3.07Å; L30-M33 VanDerWaalsContact O-N 3.17Å; L30-A34 WeakPolarHBondContact O-CB 3.35Å; L30-A34 PolarHBondContact O-N 3.16Å; L30-M39 HydrophobicContact CB-CE 3.7Å; L30-M39 HydrophobicContact CB-SD 4.23Å; L30-M39 HydrophobicContact CD1-CE 3.92Å; L30-M39 HydrophobicContact CG-CE 4.45Å; L30-V88 HydrophobicContact CD1-CG1 4.33Å; L30-M98 HydrophobicContact CB-CE 4.12Å; L30-M98 HydrophobicContact CD2-CE 3.5Å; L30-M98 HydrophobicContact CG-CE 4.31Å
31N96.3Very high95.2Very high45 Ų4554.8 Ų54.824%0.24126%0.263CS..Hα-helixtrans-57.4-45.6173.3-86.1-45.1000112.1L27 Q28 M33 A34 G35 N36 M39L27-N31 WeakPolarHBondContact O-CB 3.5Å; L27-N31 PolarHBondContact O-N 3.39Å; L27-N31 PolarHBondContact O-ND2 2.9Å; L27-N31 VanDerWaalsContact O-ND2 3.11Å; Q28-N31 PolarHBondContact O-N 3.47Å; N31-M33 VanDerWaalsContact C-N 3.35Å; N31-M33 PolarHBondContact O-N 3.17Å; N31-A34 CarbonylContact O-C 3.6Å; N31-A34 PolarHBondContact O-N 3.3Å; N31-G35 PolarHBondContact O-N 3.5Å; N31-N36 PolarHBondContact O-N 2.95Å; N31-M39 WeakPolarHBondContact OD1-CB 3.37Å; N31-M39 WeakPolarHBondContact OD1-CG 3.16Å
32K97.4Very high95.4Very high60 Ų6051.1 Ų51.126%0.26125%0.248SC..Hα-helixtrans-62.2-41.9175.4-71.8177.6173.7-147.30112.1Q28 Y29 L30 A34 G35 E113 V115Q28-K32 WeakPolarHBondContact O-CG 3.39Å; Q28-K32 PolarHBondContact O-N 3.19Å; Y29-K32 PolarHBondContact O-N 3.1Å; L30-K32 VanDerWaalsContact C-N 3.35Å; L30-K32 PolarHBondContact O-N 2.89Å; K32-A34 VanDerWaalsContact C-N 3.3Å; K32-A34 PolarHBondContact O-N 3.05Å; K32-G35 PolarHBondContact O-N 3.1Å; K32-G35 VanDerWaalsContact O-N 3.16Å; K32-E113 WeakPolarHBondContact CD-OE1 3.34Å; K32-E113 WeakPolarHBondContact CE-OE1 3.43Å; K32-E113 IonicContact NZ-OE1 2.72Å; K32-E113 PolarHBondContact NZ-OE1 3.49Å; K32-V115 HydrophobicContact CB-CB 4.49Å; K32-V115 HydrophobicContact CB-CG1 3.75Å; K32-V115 HydrophobicContact CB-CG2 3.88Å
33M97.4Very high95.6Very high19 Ų1954.2 Ų54.29%0.09427%0.266CS..Hα-helixtrans-64.4-34.9176.4-70.2-178.766.800112.7Y29 L30 N31 G35 M98 T101 L102 V115 L116Y29-M33 WeakPolarHBondContact O-CG 3.48Å; Y29-M33 PolarHBondContact O-N 3.47Å; L30-M33 WeakPolarHBondContact O-CB 3.35Å; L30-M33 PolarHBondContact O-N 3.07Å; L30-M33 VanDerWaalsContact O-N 3.17Å; N31-M33 VanDerWaalsContact C-N 3.35Å; N31-M33 PolarHBondContact O-N 3.17Å; M33-G35 VanDerWaalsContact C-N 3.27Å; M33-M98 HydrophobicContact CB-CG 4.1Å; M33-T101 HydrophobicContact CB-CG2 4.36Å; M33-T101 HydrophobicContact CG-CG2 4.21Å; M33-T101 PolarHBondContact O-OG1 3.37Å; M33-L102 HydrophobicContact CE-CD2 3.93Å; M33-L102 HydrophobicContact CE-CG 4.06Å; M33-V115 HydrophobicContact CG-CB 4.31Å; M33-V115 HydrophobicContact CG-CG1 3.66Å; M33-L116 HydrophobicContact CE-CD1 3.76Å; M33-L116 HydrophobicContact SD-CD1 3.81Å; M33-L116 HydrophobicContact SD-CG 4.34Å
34A97.3Very high95.7Very high0 Ų056.8 Ų56.80%029%0.291CS..THydrogen-bonded Turntrans-83.40.4176.600000113.1L30 N31 K32 N36 E37 M39 M98L30-A34 WeakPolarHBondContact O-CB 3.35Å; L30-A34 PolarHBondContact O-N 3.16Å; N31-A34 CarbonylContact O-C 3.6Å; N31-A34 PolarHBondContact O-N 3.3Å; K32-A34 VanDerWaalsContact C-N 3.3Å; K32-A34 PolarHBondContact O-N 3.05Å; A34-N36 VanDerWaalsContact C-N 3.32Å; A34-N36 PolarHBondContact O-N 3.23Å; A34-E37 WeakPolarHBondContact O-CB 3.48Å; A34-E37 WeakPolarHBondContact O-CG 3.3Å; A34-E37 PolarHBondContact O-N 3.43Å; A34-M39 HydrophobicContact CB-CG 4.41Å; A34-M39 HydrophobicContact CB-SD 4.33Å; A34-M98 HydrophobicContact CB-CG 3.75Å; A34-M98 HydrophobicContact CB-SD 4.31Å
35G96.2Very high95.8Very high12 Ų1255 Ų5512%0.12428%0.284CS..THydrogen-bonded Turntrans61.136.9-177.400000114.2N31 K32 M33 E37N31-G35 PolarHBondContact O-N 3.5Å; K32-G35 PolarHBondContact O-N 3.1Å; K32-G35 VanDerWaalsContact O-N 3.16Å; M33-G35 VanDerWaalsContact C-N 3.27Å; G35-E37 VanDerWaalsContact C-N 3.25Å; G35-E37 PolarHBondContact O-N 2.9Å
36N95.1Very high95.9Very high123 Ų12352.8 Ų52.866%0.65828%0.275SS*.THydrogen-bonded Turntrans63.723-176.8-49.3-56.2000114.7N31 A34N31-N36 PolarHBondContact O-N 2.95Å; A34-N36 VanDerWaalsContact C-N 3.32Å; A34-N36 PolarHBondContact O-N 3.23Å
37E95.7Very high95.9Very high65 Ų6555.5 Ų55.530%0.30429%0.286SS..  trans-72.1-178.4165.1-69.2-165.2-177.700112.3A34 G35 M39 S94A34-E37 WeakPolarHBondContact O-CB 3.48Å; A34-E37 WeakPolarHBondContact O-CG 3.3Å; A34-E37 PolarHBondContact O-N 3.43Å; G35-E37 VanDerWaalsContact C-N 3.25Å; G35-E37 PolarHBondContact O-N 2.9Å; E37-M39 PolarHBondContact O-N 3.19Å; E37-M39 VanDerWaalsContact O-N 3.16Å; E37-S94 WeakPolarHBondContact OE2-CA 3.19Å; E37-S94 PolarHBondContact OE2-N 3.04Å
38Y95.8Very high96Very high121 Ų12157 Ų5748%0.47530%0.299SS..  trans-55.3120.4-176.8179.9-93.6000112.5E89 T91 S94Y38-E89 HydrophobicContact CE1-CB 4.16Å; Y38-E89 PolarHBondContact OH-OE2 3.13Å; Y38-T91 HydrophobicContact CD1-CG2 3.77Å; Y38-T91 HydrophobicContact CE1-CG2 4.45Å; Y38-T91 HydrophobicContact CG-CG2 4.16Å; Y38-S94 VanDerWaalsContact O-CB 3.26Å; Y38-S94 WeakPolarHBondContact O-CB 3.15Å; Y38-S94 PolarHBondContact O-OG 3.48Å
39M94.8Very high95.9Very high27 Ų2755.2 Ų55.213%0.13329%0.291CS..EExtended strand (participates in β ladder)trans-130.7116.2166.5-72.2-64.9-46.600107.6L27 L30 N31 A34 E37 V88 V90 M98L27-M39 HydrophobicContact CD1-CB 4.24Å; L27-M39 HydrophobicContact CD1-CE 4.01Å; L30-M39 HydrophobicContact CB-CE 3.7Å; L30-M39 HydrophobicContact CB-SD 4.23Å; L30-M39 HydrophobicContact CD1-CE 3.92Å; L30-M39 HydrophobicContact CG-CE 4.45Å; N31-M39 WeakPolarHBondContact OD1-CB 3.37Å; N31-M39 WeakPolarHBondContact OD1-CG 3.16Å; A34-M39 HydrophobicContact CB-CG 4.41Å; A34-M39 HydrophobicContact CB-SD 4.33Å; E37-M39 PolarHBondContact O-N 3.19Å; E37-M39 VanDerWaalsContact O-N 3.16Å; M39-V88 HydrophobicContact CE-CG1 3.25Å; M39-V90 HydrophobicContact CE-CG1 3.77Å; M39-V90 HydrophobicContact SD-CG1 3.52Å; M39-V90 VanDerWaalsContact SD-CG1 3.52Å; M39-M98 HydrophobicContact SD-SD 4.08Å
40G94.1Very high95.9Very high11 Ų1153.6 Ų53.611%0.11329%0.286CS..EExtended strand (participates in β ladder)trans-112.9176.6-179.100000112.9E89G40-E89 PolarHBondContact N-O 3.41Å; G40-E89 PolarHBondContact O-N 2.95Å
41F96.4Very high95.8Very high71 Ų7158.8 Ų58.831%0.31131%0.309SS..EExtended strand (participates in β ladder)trans-142.8123.1172.5173.8-103.1000109.8F23 N43 F46 Q84F23-F41 HydrophobicContact CE2-CD2 4.04Å; F23-F41 HydrophobicContact CE2-CE2 4.22Å; F23-F41 HydrophobicContact CZ-CB 4.28Å; F23-F41 AromaticContact CZ-CD2 3.55Å; F23-F41 HydrophobicContact CZ-CD2 3.55Å; F23-F41 HydrophobicContact CZ-CE2 4.05Å; F23-F41 AromaticContact CZ-CG 3.96Å; F23-F41 HydrophobicContact CZ-CG 3.96Å; F41-N43 HydrophobicContact CD1-CB 4.48Å; F41-N43 HydrophobicContact CE1-CB 3.93Å; F41-F46 HydrophobicContact CE2-CB 4.31Å; F41-F46 HydrophobicContact CZ-CB 3.82Å; F41-F46 HydrophobicContact CZ-CD1 4.27Å; F41-F46 HydrophobicContact CZ-CG 4Å; F41-Q84 HydrophobicContact CE2-CB 4.21Å; F41-Q84 HydrophobicContact CE2-CG 4.48Å; F41-Q84 WeakPolarHBondContact CE2-O 3.42Å; F41-Q84 HydrophobicContact CZ-CG 4.48Å
42S96.7Very high95.6Very high17 Ų1761.1 Ų61.112%0.11933%0.325CS..  trans-94.7101.1176.5177.80000110.7A44 T45 F46 S87 E89S42-A44 PolarHBondContact O-N 2.89Å; S42-T45 PolarHBondContact O-N 3.46Å; S42-T45 WeakPolarHBondContact OG-CB 3.44Å; S42-T45 PolarHBondContact OG-N 2.98Å; S42-T45 VanDerWaalsContact OG-N 3.09Å; S42-T45 PolarHBondContact OG-OG1 2.98Å; S42-F46 WeakPolarHBondContact O-CB 3.43Å; S42-F46 PolarHBondContact O-N 3.23Å; S42-S87 PolarHBondContact N-O 3.42Å; S42-E89 WeakPolarHBondContact CB-OE1 3.43Å
43N96.2Very high95.4Very high90 Ų9058.5 Ų58.548%0.48132%0.315SS..Hα-helixtrans-64.6-30.2172.9-173.453.4000111.9F41 F46 Q47F41-N43 HydrophobicContact CD1-CB 4.48Å; F41-N43 HydrophobicContact CE1-CB 3.93Å; N43-F46 PolarHBondContact O-N 3.31Å; N43-Q47 WeakPolarHBondContact O-CG 3.35Å; N43-Q47 PolarHBondContact O-N 2.89Å
44A96.8Very high95.3Very high77 Ų7763.4 Ų63.464%0.63634%0.341SS*.Hα-helixtrans-64.9-47.5177.800000111.4S42 F46 Q47 S48S42-A44 PolarHBondContact O-N 2.89Å; A44-F46 VanDerWaalsContact C-N 3.33Å; A44-F46 PolarHBondContact O-N 3.2Å; A44-Q47 PolarHBondContact O-N 3.41Å; A44-S48 WeakPolarHBondContact O-CB 3.46Å; A44-S48 PolarHBondContact O-N 3.24Å
45T95.4Very high95.2Very high60 Ų6072.7 Ų72.737%0.36838%0.376SS..Hα-helixtrans-63.8-40.6175.2-54.80000110.9S42 Q47 S48 E49S42-T45 PolarHBondContact O-N 3.46Å; S42-T45 WeakPolarHBondContact OG-CB 3.44Å; S42-T45 PolarHBondContact OG-N 2.98Å; S42-T45 VanDerWaalsContact OG-N 3.09Å; S42-T45 PolarHBondContact OG-OG1 2.98Å; T45-Q47 PolarHBondContact O-N 3.34Å; T45-S48 PolarHBondContact O-N 2.71Å; T45-E49 HydrophobicContact CG2-CG 4.06Å; T45-E49 WeakPolarHBondContact O-CB 3.26Å; T45-E49 WeakPolarHBondContact O-CG 3.46Å; T45-E49 PolarHBondContact O-N 2.9Å
46F96.5Very high95.2Very high17 Ų1772.6 Ų72.68%0.07537%0.373CS..Hα-helixtrans-57.6-49.3176.6166.9-113.8000113F41 S42 N43 A44 K50 F83 Q84 S87F41-F46 HydrophobicContact CE2-CB 4.31Å; F41-F46 HydrophobicContact CZ-CB 3.82Å; F41-F46 HydrophobicContact CZ-CD1 4.27Å; F41-F46 HydrophobicContact CZ-CG 4Å; S42-F46 WeakPolarHBondContact O-CB 3.43Å; S42-F46 PolarHBondContact O-N 3.23Å; N43-F46 PolarHBondContact O-N 3.31Å; A44-F46 VanDerWaalsContact C-N 3.33Å; A44-F46 PolarHBondContact O-N 3.2Å; F46-K50 HydrophobicContact CE2-CD 4.33Å; F46-K50 HydrophobicContact CZ-CD 4.02Å; F46-K50 WeakPolarHBondContact O-CB 3.23Å; F46-K50 PolarHBondContact O-N 2.89Å; F46-F83 HydrophobicContact CD2-CB 3.76Å; F46-F83 HydrophobicContact CE2-CB 3.69Å; F46-Q84 HydrophobicContact CD2-CG 3.91Å; F46-Q84 HydrophobicContact CE2-CG 3.56Å; F46-Q84 HydrophobicContact CZ-CG 3.99Å; F46-S87 WeakPolarHBondContact CA-OG 3.45Å; F46-S87 PolarHBondContact N-OG 2.87Å
47Q95.8Very high95.3Very high78 Ų7869 Ų6936%0.36435%0.351SS..Hα-helixtrans-65.1-43.3178.3-63.9-59.3-22.800111.1N43 A44 T45 E49 K50 E51N43-Q47 WeakPolarHBondContact O-CG 3.35Å; N43-Q47 PolarHBondContact O-N 2.89Å; A44-Q47 PolarHBondContact O-N 3.41Å; T45-Q47 PolarHBondContact O-N 3.34Å; Q47-E49 PolarHBondContact O-N 2.96Å; Q47-K50 PolarHBondContact O-N 3.07Å; Q47-E51 WeakPolarHBondContact O-CB 3.36Å; Q47-E51 WeakPolarHBondContact O-CG 3.43Å; Q47-E51 PolarHBondContact O-N 3.08Å
48S95.7Very high95.4Very high64 Ų6469 Ų6945%0.44836%0.361SS..Hα-helixtrans-61.4-46.4178.9-176.30000112.8A44 T45 K50 E51 T52A44-S48 WeakPolarHBondContact O-CB 3.46Å; A44-S48 PolarHBondContact O-N 3.24Å; T45-S48 PolarHBondContact O-N 2.71Å; S48-K50 VanDerWaalsContact C-N 3.31Å; S48-K50 PolarHBondContact O-N 3.37Å; S48-E51 PolarHBondContact O-N 3.43Å; S48-T52 WeakPolarHBondContact O-CB 3.5Å; S48-T52 PolarHBondContact O-N 3.05Å; S48-T52 PolarHBondContact O-OG1 3.45Å
49E94.1Very high95.4Very high73 Ų7365 Ų6534%0.34135%0.348SS..Hα-helixtrans-66.2-34.1176.7-76.2-70.5157.400111.9T45 Q47 G53 F83T45-E49 HydrophobicContact CG2-CG 4.06Å; T45-E49 WeakPolarHBondContact O-CB 3.26Å; T45-E49 WeakPolarHBondContact O-CG 3.46Å; T45-E49 PolarHBondContact O-N 2.9Å; Q47-E49 PolarHBondContact O-N 2.96Å; E49-G53 WeakPolarHBondContact O-CA 3.35Å; E49-G53 PolarHBondContact O-N 3.09Å; E49-F83 HydrophobicContact CB-CD1 4.16Å; E49-F83 WeakPolarHBondContact O-CE1 3.33Å
50K93.8Very high95.5Very high58 Ų5863.7 Ų63.725%0.25234%0.341SS..Hα-helixtrans-72.1-37.2177.2-176.7172.9173.91620112.5F46 Q47 S48 Y57 D80 F83F46-K50 HydrophobicContact CE2-CD 4.33Å; F46-K50 HydrophobicContact CZ-CD 4.02Å; F46-K50 WeakPolarHBondContact O-CB 3.23Å; F46-K50 PolarHBondContact O-N 2.89Å; Q47-K50 PolarHBondContact O-N 3.07Å; S48-K50 VanDerWaalsContact C-N 3.31Å; S48-K50 PolarHBondContact O-N 3.37Å; K50-Y57 VanDerWaalsContact CG-OH 3.28Å; K50-Y57 WeakPolarHBondContact CG-OH 3.4Å; K50-Y57 WeakPolarHBondContact O-CE2 3.34Å; K50-Y57 PolarHBondContact O-OH 3.44Å; K50-Y57 VanDerWaalsContact O-OH 3.07Å; K50-D80 WeakPolarHBondContact CE-OD1 3.49Å; K50-D80 IonicContact NZ-OD1 3.04Å; K50-D80 PolarHBondContact NZ-OD1 2.88Å; K50-D80 IonicContact NZ-OD2 3.34Å; K50-F83 HydrophobicContact CB-CD2 4.33Å; K50-F83 HydrophobicContact CG-CD2 4.29Å; K50-F83 HydrophobicContact CG-CE2 4.42Å
51E94.3Very high95.7Very high147 Ų14769.3 Ų69.369%0.68736%0.36SS*.Hα-helixtrans-73-37.7177.5-75.4176.1-176.600112.1Q47 S48Q47-E51 WeakPolarHBondContact O-CB 3.36Å; Q47-E51 WeakPolarHBondContact O-CG 3.43Å; Q47-E51 PolarHBondContact O-N 3.08Å; S48-E51 PolarHBondContact O-N 3.43Å
52T93.2Very high95.7Very high94 Ų9473.2 Ų73.258%0.57737%0.374SS*.Hα-helixtrans-99.91.3-176.260.50000113.9S48 D54S48-T52 WeakPolarHBondContact O-CB 3.5Å; S48-T52 PolarHBondContact O-N 3.05Å; S48-T52 PolarHBondContact O-OG1 3.45Å; T52-D54 PolarHBondContact O-N 3.2Å
53G92Very high95.8Very high5 Ų573.4 Ų73.45%0.05237%0.374CS..  trans-7830.7-174.200000116.1E49 R55 N56 Y57E49-G53 WeakPolarHBondContact O-CA 3.35Å; E49-G53 PolarHBondContact O-N 3.09Å; G53-R55 VanDerWaalsContact C-N 3.25Å; G53-R55 PolarHBondContact O-N 3.37Å; G53-R55 VanDerWaalsContact O-N 3.12Å; G53-N56 WeakPolarHBondContact O-CB 3.44Å; G53-N56 PolarHBondContact O-N 3.28Å; G53-Y57 VanDerWaalsContact O-CD2 3.3Å; G53-Y57 WeakPolarHBondContact O-CD2 3.37Å; G53-Y57 PolarHBondContact O-N 3.3Å
54D94.8Very high95.7Very high121 Ų12174.5 Ų74.565%0.64737%0.374SS*.Hα-helixtrans-49.5-43.1-172.5-70.6-34.6000113.5T52 N56 Y57 A58T52-D54 PolarHBondContact O-N 3.2Å; D54-N56 VanDerWaalsContact C-N 3.3Å; D54-N56 PolarHBondContact O-N 2.87Å; D54-Y57 PolarHBondContact O-N 3.06Å; D54-A58 PolarHBondContact O-N 3.49Å; D54-A58 VanDerWaalsContact O-N 3.08Å
55R95.4Very high95.8Very high195 Ų19578.2 Ų78.274%0.73638%0.378SS*.Hα-helixtrans-60.3-39.6178.4-175.6-179.9179.1-177.91.2112.1G53 A58 I59G53-R55 VanDerWaalsContact C-N 3.25Å; G53-R55 PolarHBondContact O-N 3.37Å; G53-R55 VanDerWaalsContact O-N 3.12Å; R55-A58 PolarHBondContact O-N 2.86Å; R55-I59 HydrophobicContact CG-CD1 4.08Å; R55-I59 WeakPolarHBondContact O-CD1 3.42Å; R55-I59 VanDerWaalsContact O-CG1 3.29Å; R55-I59 WeakPolarHBondContact O-CG1 3.44Å; R55-I59 PolarHBondContact O-N 2.92Å; R55-I59 VanDerWaalsContact O-N 3.07Å
56N96.7Very high95.8Very high11 Ų1181.5 Ų81.56%0.05939%0.387CS..Hα-helixtrans-71.1-35.4-178.8-64.1-39.7000110.9N3 I7 G53 D54 I59 G60 L79 F83N3-N56 PolarHBondContact ND2-OD1 3.1Å; I7-N56 HydrophobicContact CD1-CB 4.26Å; G53-N56 WeakPolarHBondContact O-CB 3.44Å; G53-N56 PolarHBondContact O-N 3.28Å; D54-N56 VanDerWaalsContact C-N 3.3Å; D54-N56 PolarHBondContact O-N 2.87Å; N56-I59 PolarHBondContact O-N 2.89Å; N56-G60 PolarHBondContact O-N 3.25Å; N56-L79 HydrophobicContact CB-CD1 4.31Å; N56-L79 WeakPolarHBondContact O-CD1 3.33Å; N56-F83 HydrophobicContact CB-CE1 4.31Å; N56-F83 HydrophobicContact CB-CZ 3.98Å
57Y96.6Very high95.8Very high48 Ų4889.6 Ų89.619%0.18842%0.422CS..Hα-helixtrans-61.8-47.3171.6-70.5-77000111.8K50 G53 D54 I59 G60 Y61 M76 L79 F83K50-Y57 VanDerWaalsContact CG-OH 3.28Å; K50-Y57 WeakPolarHBondContact CG-OH 3.4Å; K50-Y57 WeakPolarHBondContact O-CE2 3.34Å; K50-Y57 PolarHBondContact O-OH 3.44Å; K50-Y57 VanDerWaalsContact O-OH 3.07Å; G53-Y57 VanDerWaalsContact O-CD2 3.3Å; G53-Y57 WeakPolarHBondContact O-CD2 3.37Å; G53-Y57 PolarHBondContact O-N 3.3Å; D54-Y57 PolarHBondContact O-N 3.06Å; Y57-I59 VanDerWaalsContact C-N 3.31Å; Y57-I59 PolarHBondContact O-N 3.34Å; Y57-G60 PolarHBondContact O-N 2.96Å; Y57-G60 VanDerWaalsContact O-N 3.09Å; Y57-Y61 VanDerWaalsContact O-CD2 3.23Å; Y57-Y61 WeakPolarHBondContact O-CD2 3.34Å; Y57-Y61 PolarHBondContact O-N 3.04Å; Y57-M76 HydrophobicContact CE1-CE 4.08Å; Y57-M76 HydrophobicContact CE1-SD 4.47Å; Y57-L79 HydrophobicContact CD1-CD2 3.25Å; Y57-L79 HydrophobicContact CD2-CD2 4.46Å; Y57-L79 HydrophobicContact CE1-CD2 3.26Å; Y57-L79 HydrophobicContact CE2-CD2 4.47Å; Y57-L79 HydrophobicContact CG-CD2 3.89Å; Y57-F83 HydrophobicContact CE2-CE2 4.28Å; Y57-F83 HydrophobicContact CE2-CZ 4.3Å
58A97.6Very high95.9Very high64 Ų6488.6 Ų88.653%0.52942%0.424SS..Hα-helixtrans-58.4-43.4177.700000112D54 R55 Y62D54-A58 PolarHBondContact O-N 3.49Å; D54-A58 VanDerWaalsContact O-N 3.08Å; R55-A58 PolarHBondContact O-N 2.86Å; A58-Y62 WeakPolarHBondContact O-CB 3.45Å; A58-Y62 PolarHBondContact O-N 3.33Å
59I97.4Very high95.8Very high36 Ų3686.8 Ų86.819%0.18541%0.408CS..Hα-helixtrans-60.7-46.5173.9-68.6164.2000110.6A4 I7 R55 N56 Y57 Y61 Y62 L63A4-I59 HydrophobicContact CB-CG2 3.69Å; I7-I59 HydrophobicContact CD1-CB 4.5Å; I7-I59 HydrophobicContact CD1-CG2 4.08Å; R55-I59 HydrophobicContact CG-CD1 4.08Å; R55-I59 WeakPolarHBondContact O-CD1 3.42Å; R55-I59 VanDerWaalsContact O-CG1 3.29Å; R55-I59 WeakPolarHBondContact O-CG1 3.44Å; R55-I59 PolarHBondContact O-N 2.92Å; R55-I59 VanDerWaalsContact O-N 3.07Å; N56-I59 PolarHBondContact O-N 2.89Å; Y57-I59 VanDerWaalsContact C-N 3.31Å; Y57-I59 PolarHBondContact O-N 3.34Å; I59-Y61 PolarHBondContact O-N 3.11Å; I59-Y62 PolarHBondContact O-N 2.91Å; I59-L63 HydrophobicContact CG2-CD1 3.64Å; I59-L63 HydrophobicContact CG2-CG 4.13Å; I59-L63 WeakPolarHBondContact O-CB 3.3Å; I59-L63 VanDerWaalsContact O-CG 3.26Å; I59-L63 WeakPolarHBondContact O-CG 3.44Å; I59-L63 PolarHBondContact O-N 3.15Å
60G96.7Very high95.8Very high0 Ų085 Ų850%040%0.402CS..Hα-helixtrans-56.8-48.2179.200000112.8N56 Y57 L63 K64 M75N56-G60 PolarHBondContact O-N 3.25Å; Y57-G60 PolarHBondContact O-N 2.96Å; Y57-G60 VanDerWaalsContact O-N 3.09Å; G60-L63 PolarHBondContact O-N 2.95Å; G60-K64 WeakPolarHBondContact O-CB 3.26Å; G60-K64 PolarHBondContact O-N 2.9Å; G60-M75 WeakPolarHBondContact O-CG 3.32Å
61Y97.3Very high95.7Very high130 Ų13092.5 Ų92.551%0.5144%0.435SS..Hα-helixtrans-63.6-41.5176.4-78.2-70.8000112.6Y57 I59 L63 K64 E65 M75Y57-Y61 VanDerWaalsContact O-CD2 3.23Å; Y57-Y61 WeakPolarHBondContact O-CD2 3.34Å; Y57-Y61 PolarHBondContact O-N 3.04Å; I59-Y61 PolarHBondContact O-N 3.11Å; Y61-L63 PolarHBondContact O-N 3.34Å; Y61-K64 WeakPolarHBondContact O-CB 3.49Å; Y61-K64 PolarHBondContact O-N 3.21Å; Y61-E65 PolarHBondContact O-N 3.08Å; Y61-M75 HydrophobicContact CD1-CE 3.68Å; Y61-M75 HydrophobicContact CD2-CE 4.1Å; Y61-M75 HydrophobicContact CE1-CE 3.57Å; Y61-M75 HydrophobicContact CE2-CE 4Å; Y61-M75 HydrophobicContact CG-CE 3.94Å
62Y97.6Very high95.3Very high152 Ų15289.8 Ų89.860%0.59645%0.446SS*.Hα-helixtrans-62.3-44.2177.2-169.6-89.3000112.2A58 I59 K64 E65 K66A58-Y62 WeakPolarHBondContact O-CB 3.45Å; A58-Y62 PolarHBondContact O-N 3.33Å; I59-Y62 PolarHBondContact O-N 2.91Å; Y62-K64 VanDerWaalsContact C-N 3.32Å; Y62-K64 PolarHBondContact O-N 3.4Å; Y62-E65 PolarHBondContact O-N 2.94Å; Y62-K66 HydrophobicContact CD1-CG 4.32Å; Y62-K66 HydrophobicContact CE1-CG 3.95Å; Y62-K66 WeakPolarHBondContact O-CG 3.5Å; Y62-K66 PolarHBondContact O-N 2.73Å; Y62-K66 VanDerWaalsContact O-N 3.12Å
63L97.2Very high95Very high22 Ų2287.1 Ų87.112%0.11543%0.43CS..Hα-helixtrans-64.4-36.4176.6-70.3172.1000112.2I7 V8 I59 G60 Y61 K66 K67 C68 F69I7-L63 HydrophobicContact CG2-CD1 4.37Å; V8-L63 HydrophobicContact CG2-CD1 3.86Å; V8-L63 HydrophobicContact CG2-CD2 4.28Å; I59-L63 HydrophobicContact CG2-CD1 3.64Å; I59-L63 HydrophobicContact CG2-CG 4.13Å; I59-L63 WeakPolarHBondContact O-CB 3.3Å; I59-L63 VanDerWaalsContact O-CG 3.26Å; I59-L63 WeakPolarHBondContact O-CG 3.44Å; I59-L63 PolarHBondContact O-N 3.15Å; G60-L63 PolarHBondContact O-N 2.95Å; Y61-L63 PolarHBondContact O-N 3.34Å; L63-K66 PolarHBondContact O-N 3.5Å; L63-K67 PolarHBondContact O-N 3.44Å; L63-C68 HydrophobicContact CB-CB 4.08Å; L63-C68 HydrophobicContact CD2-CB 3.81Å; L63-C68 WeakPolarHBondContact O-CB 3.39Å; L63-C68 PolarHBondContact O-N 3.33Å; L63-F69 HydrophobicContact CB-CD2 4.47Å; L63-F69 HydrophobicContact CB-CE2 3.66Å; L63-F69 HydrophobicContact CB-CZ 3.84Å; L63-F69 HydrophobicContact CD1-CZ 4.18Å
64K96Very high95Very high113 Ų11390.6 Ų90.649%0.49145%0.447SS..Hα-helixtrans-63.2-48.6176.1-174.3178.6-178175.40111.2G60 Y61 Y62 K66 K67 F69 M75G60-K64 WeakPolarHBondContact O-CB 3.26Å; G60-K64 PolarHBondContact O-N 2.9Å; Y61-K64 WeakPolarHBondContact O-CB 3.49Å; Y61-K64 PolarHBondContact O-N 3.21Å; Y62-K64 VanDerWaalsContact C-N 3.32Å; Y62-K64 PolarHBondContact O-N 3.4Å; K64-K66 VanDerWaalsContact C-N 3.28Å; K64-K66 PolarHBondContact O-N 3.37Å; K64-K67 PolarHBondContact O-N 3.34Å; K64-K67 VanDerWaalsContact O-N 3.09Å; K64-F69 HydrophobicContact CB-CD2 4.29Å; K64-F69 HydrophobicContact CB-CE2 4.14Å; K64-M75 HydrophobicContact CB-CB 4.42Å; K64-M75 HydrophobicContact CB-CG 4.33Å; K64-M75 HydrophobicContact CD-CB 4.01Å; K64-M75 HydrophobicContact CD-CE 4.46Å; K64-M75 HydrophobicContact CG-CB 4.46Å
65E96.9Very high94.9Very high154 Ų15485 Ų8572%0.7242%0.417SS*.Hα-helixtrans-59.6-39.8178.1-176.860.9-162.600111.8Y61 Y62 K67Y61-E65 PolarHBondContact O-N 3.08Å; Y62-E65 PolarHBondContact O-N 2.94Å; E65-K67 PolarHBondContact O-N 2.92Å
66K97.3Very high94.8Very high130 Ų13078.9 Ų78.957%0.56540%0.398SS*.THydrogen-bonded Turntrans-81.56.1178.4-64.6-60.4-175.2-175.70114.8Y62 L63 K64 C68Y62-K66 HydrophobicContact CD1-CG 4.32Å; Y62-K66 HydrophobicContact CE1-CG 3.95Å; Y62-K66 WeakPolarHBondContact O-CG 3.5Å; Y62-K66 PolarHBondContact O-N 2.73Å; Y62-K66 VanDerWaalsContact O-N 3.12Å; L63-K66 PolarHBondContact O-N 3.5Å; K64-K66 VanDerWaalsContact C-N 3.28Å; K64-K66 PolarHBondContact O-N 3.37Å; K66-C68 PolarHBondContact O-N 2.96Å
67K96.3Very high94.6Very high186 Ų18679.5 Ų79.581%0.80940%0.404SS*.THydrogen-bonded Turntrans5637.5179.3-54.9177.6-178.6175.40112.8L63 K64 E65 F69L63-K67 PolarHBondContact O-N 3.44Å; K64-K67 PolarHBondContact O-N 3.34Å; K64-K67 VanDerWaalsContact O-N 3.09Å; E65-K67 PolarHBondContact O-N 2.92Å; K67-F69 VanDerWaalsContact C-N 3.27Å; K67-F69 PolarHBondContact O-N 3.08Å
68C96.5Very high94.4Very high58 Ų5877.4 Ų77.439%0.39240%0.397SS..  trans-76.5-14.8178.4-61.90000113.1L63 K66L63-C68 HydrophobicContact CB-CB 4.08Å; L63-C68 HydrophobicContact CD2-CB 3.81Å; L63-C68 WeakPolarHBondContact O-CB 3.39Å; L63-C68 PolarHBondContact O-N 3.33Å; K66-C68 PolarHBondContact O-N 2.96Å
69F95.3Very high94.3Very high26 Ų2674.4 Ų74.411%0.11437%0.372CS..SBendtrans-89.9152.4177.7-61.9-67.4000111.9I7 V8 L63 K64 K67 M75I7-F69 HydrophobicContact CG2-CE1 4.06Å; I7-F69 HydrophobicContact CG2-CZ 4.02Å; V8-F69 HydrophobicContact CG2-CE1 4.41Å; L63-F69 HydrophobicContact CB-CD2 4.47Å; L63-F69 HydrophobicContact CB-CE2 3.66Å; L63-F69 HydrophobicContact CB-CZ 3.84Å; L63-F69 HydrophobicContact CD1-CZ 4.18Å; K64-F69 HydrophobicContact CB-CD2 4.29Å; K64-F69 HydrophobicContact CB-CE2 4.14Å; K67-F69 VanDerWaalsContact C-N 3.27Å; K67-F69 PolarHBondContact O-N 3.08Å; F69-M75 HydrophobicContact CD2-CB 4.41Å; F69-M75 HydrophobicContact CD2-CG 4.5Å; F69-M75 HydrophobicContact CE2-CB 4Å; F69-M75 HydrophobicContact CE2-CG 3.63Å; F69-M75 HydrophobicContact CZ-CB 4.49Å; F69-M75 HydrophobicContact CZ-CG 3.92Å
70P93.3Very high94.1Very high35 Ų3573.7 Ų73.723%0.22737%0.368CS..PPolyproline II helixtrans-58154.1171.3-18.829.7000112.1S11 L12 M15 G72 V73S11-P70 WeakPolarHBondContact OG-CD 3.45Å; L12-P70 HydrophobicContact CD2-CG 3.48Å; L12-P70 VanDerWaalsContact CD2-CG 3.48Å; M15-P70 HydrophobicContact SD-CB 4.05Å; M15-P70 HydrophobicContact SD-CG 4.15Å; P70-G72 PolarHBondContact O-N 3.45Å; P70-V73 HydrophobicContact CB-CG2 3.86Å; P70-V73 HydrophobicContact CG-CG2 4.13Å; P70-V73 PolarHBondContact O-N 3.28Å
71K90.9Very high94Very high216 Ų21673.9 Ų73.994%0.93937%0.369SS*.THydrogen-bonded Turntrans-60.3129.8179.4-66.8-176.1-179.5178.80110.3
72G85.7Confident94Very high89 Ų8968.7 Ų68.792%0.91835%0.349SS*.THydrogen-bonded Turntrans85.7-1.4176.200000115.4P70P70-G72 PolarHBondContact O-N 3.45Å
73V88.5Confident93.9Very high39 Ų3961.5 Ų61.524%0.23632%0.321CS..  trans-83.9132.2178-179.70000111.1P70P70-V73 HydrophobicContact CB-CG2 3.86Å; P70-V73 HydrophobicContact CG-CG2 4.13Å; P70-V73 PolarHBondContact O-N 3.28Å
74D91.3Very high93.9Very high78 Ų7862.4 Ų62.442%0.41732%0.324SS..  trans-77.5125.9170.9175.132.9000111.2M76 A77 A78D74-M76 PolarHBondContact OD1-N 3.23Å; D74-M76 VanDerWaalsContact OD1-N 3.11Å; D74-A77 HydrophobicContact CB-CB 3.96Å; D74-A77 PolarHBondContact O-N 3.47Å; D74-A77 PolarHBondContact OD2-N 3.48Å; D74-A78 PolarHBondContact O-N 3.38Å; D74-A78 VanDerWaalsContact O-N 3.15Å
75M93.4Very high93.9Very high3 Ų359 Ų592%0.01531%0.311CS..Hα-helixtrans-62.1-42177.2178.7-82.7-7100111.6G60 Y61 K64 F69 A77 A78 L79G60-M75 WeakPolarHBondContact O-CG 3.32Å; Y61-M75 HydrophobicContact CD1-CE 3.68Å; Y61-M75 HydrophobicContact CD2-CE 4.1Å; Y61-M75 HydrophobicContact CE1-CE 3.57Å; Y61-M75 HydrophobicContact CE2-CE 4Å; Y61-M75 HydrophobicContact CG-CE 3.94Å; K64-M75 HydrophobicContact CB-CB 4.42Å; K64-M75 HydrophobicContact CB-CG 4.33Å; K64-M75 HydrophobicContact CD-CB 4.01Å; K64-M75 HydrophobicContact CD-CE 4.46Å; K64-M75 HydrophobicContact CG-CB 4.46Å; F69-M75 HydrophobicContact CD2-CB 4.41Å; F69-M75 HydrophobicContact CD2-CG 4.5Å; F69-M75 HydrophobicContact CE2-CB 4Å; F69-M75 HydrophobicContact CE2-CG 3.63Å; F69-M75 HydrophobicContact CZ-CB 4.49Å; F69-M75 HydrophobicContact CZ-CG 3.92Å; M75-A77 VanDerWaalsContact C-N 3.32Å; M75-A77 PolarHBondContact O-N 3.41Å; M75-A78 PolarHBondContact O-N 3.12Å; M75-L79 PolarHBondContact O-N 2.77Å
76M92.6Very high93.8Very high67 Ų6755.1 Ų55.133%0.3330%0.3SS..Hα-helixtrans-66.9-38.1-177.9-67-65.4-77.100110.8Y57 D74 L79 D80Y57-M76 HydrophobicContact CE1-CE 4.08Å; Y57-M76 HydrophobicContact CE1-SD 4.47Å; D74-M76 PolarHBondContact OD1-N 3.23Å; D74-M76 VanDerWaalsContact OD1-N 3.11Å; M76-L79 PolarHBondContact O-N 2.99Å; M76-D80 WeakPolarHBondContact O-CB 3.45Å; M76-D80 PolarHBondContact O-N 3.1Å
77A91.8Very high93.8Very high23 Ų2349.1 Ų49.119%0.1928%0.275CS..Hα-helixtrans-61.3-42.5172.100000113.5K19 D74 M75 L79 L81K19-A77 HydrophobicContact CD-CB 4.41Å; K19-A77 VanDerWaalsContact CE-CB 3.47Å; K19-A77 HydrophobicContact CG-CB 4.4Å; D74-A77 HydrophobicContact CB-CB 3.96Å; D74-A77 PolarHBondContact O-N 3.47Å; D74-A77 PolarHBondContact OD2-N 3.48Å; M75-A77 VanDerWaalsContact C-N 3.32Å; M75-A77 PolarHBondContact O-N 3.41Å; A77-L79 VanDerWaalsContact C-N 3.34Å; A77-L81 PolarHBondContact O-N 2.99Å; A77-L81 VanDerWaalsContact O-N 3.1Å
78A93.1Very high93.8Very high4 Ų441.7 Ų41.73%0.03325%0.245CC..Hα-helixtrans-65.7-37.8176.600000112D74 M75 Y82D74-A78 PolarHBondContact O-N 3.38Å; D74-A78 VanDerWaalsContact O-N 3.15Å; M75-A78 PolarHBondContact O-N 3.12Å; A78-Y82 WeakPolarHBondContact O-CB 3.36Å; A78-Y82 PolarHBondContact O-N 3.11Å
79L94.8Very high93.8Very high1 Ų142.9 Ų42.91%0.00525%0.245CC..Hα-helixtrans-69.1-42.7177.6-156.689.7000112.1I7 N56 Y57 M75 M76 A77 L81 Y82 F83I7-L79 HydrophobicContact CD1-CD1 3.9Å; I7-L79 HydrophobicContact CG1-CD1 4.25Å; I7-L79 HydrophobicContact CG2-CD1 4.25Å; N56-L79 HydrophobicContact CB-CD1 4.31Å; N56-L79 WeakPolarHBondContact O-CD1 3.33Å; Y57-L79 HydrophobicContact CD1-CD2 3.25Å; Y57-L79 HydrophobicContact CD2-CD2 4.46Å; Y57-L79 HydrophobicContact CE1-CD2 3.26Å; Y57-L79 HydrophobicContact CE2-CD2 4.47Å; Y57-L79 HydrophobicContact CG-CD2 3.89Å; M75-L79 PolarHBondContact O-N 2.77Å; M76-L79 PolarHBondContact O-N 2.99Å; A77-L79 VanDerWaalsContact C-N 3.34Å; L79-L81 PolarHBondContact O-N 3.1Å; L79-Y82 WeakPolarHBondContact O-CB 3.28Å; L79-Y82 PolarHBondContact O-N 3.33Å; L79-F83 HydrophobicContact CD2-CD2 4.35Å; L79-F83 HydrophobicContact CD2-CE2 3.5Å; L79-F83 HydrophobicContact CD2-CZ 4.19Å; L79-F83 HydrophobicContact CG-CD2 4.21Å; L79-F83 HydrophobicContact CG-CE2 3.69Å; L79-F83 HydrophobicContact CG-CZ 4.37Å; L79-F83 WeakPolarHBondContact O-CD2 3.33Å; L79-F83 PolarHBondContact O-N 3.3Å
80D94.1Very high93.8Very high21 Ų2144.4 Ų44.411%0.11226%0.256CS..Hα-helixtrans-58.4-48.1174.2-81.8-26.4000111K19 K50 M76 Y82 F83 Q84K19-D80 IonicContact NZ-OD2 2.73Å; K19-D80 PolarHBondContact NZ-OD2 2.97Å; K50-D80 WeakPolarHBondContact CE-OD1 3.49Å; K50-D80 IonicContact NZ-OD1 3.04Å; K50-D80 PolarHBondContact NZ-OD1 2.88Å; K50-D80 IonicContact NZ-OD2 3.34Å; M76-D80 WeakPolarHBondContact O-CB 3.45Å; M76-D80 PolarHBondContact O-N 3.1Å; D80-Y82 VanDerWaalsContact C-N 3.31Å; D80-Y82 PolarHBondContact O-N 3.3Å; D80-F83 PolarHBondContact O-N 3.07Å; D80-Q84 WeakPolarHBondContact O-CG 3.3Å; D80-Q84 PolarHBondContact O-N 3.4Å
81L94.9Very high94Very high4 Ų445.5 Ų45.52%0.02126%0.262CS..Hα-helixtrans-61.8-40.8177.2-178.463.4000111.1K22 F23 A77 L79 F83 Q84 L85K22-L81 HydrophobicContact CB-CD1 4.26Å; K22-L81 HydrophobicContact CB-CD2 3.97Å; K22-L81 HydrophobicContact CD-CD2 4.06Å; F23-L81 HydrophobicContact CB-CD1 4.22Å; F23-L81 HydrophobicContact CD2-CD1 4.5Å; A77-L81 PolarHBondContact O-N 2.99Å; A77-L81 VanDerWaalsContact O-N 3.1Å; L79-L81 PolarHBondContact O-N 3.1Å; L81-F83 PolarHBondContact O-N 3.28Å; L81-Q84 PolarHBondContact O-N 2.88Å; L81-L85 HydrophobicContact CD1-CD1 4.38Å; L81-L85 HydrophobicContact CD1-CG 4.2Å; L81-L85 HydrophobicContact CG-CD1 4.11Å; L81-L85 HydrophobicContact CG-CG 4.33Å; L81-L85 WeakPolarHBondContact O-CB 3.23Å; L81-L85 VanDerWaalsContact O-CG 3.26Å; L81-L85 WeakPolarHBondContact O-CG 3.29Å; L81-L85 PolarHBondContact O-N 3.38Å
82Y96.6Very high94.4Very high22 Ų2237.7 Ų37.79%0.08624%0.235CC..Hα-helixtrans-56.5-48.6174166.8-93.3000112.1N3 A6 I7 A78 L79 D80 Q84 L85 C86N3-Y82 PolarHBondContact ND2-OH 3.07Å; A6-Y82 HydrophobicContact CB-CD2 4.08Å; A6-Y82 HydrophobicContact CB-CE2 3.75Å; I7-Y82 HydrophobicContact CG1-CD1 4.14Å; I7-Y82 HydrophobicContact CG1-CD2 3.89Å; I7-Y82 HydrophobicContact CG1-CE1 4.44Å; I7-Y82 HydrophobicContact CG1-CE2 4.2Å; I7-Y82 HydrophobicContact CG1-CG 3.86Å; A78-Y82 WeakPolarHBondContact O-CB 3.36Å; A78-Y82 PolarHBondContact O-N 3.11Å; L79-Y82 WeakPolarHBondContact O-CB 3.28Å; L79-Y82 PolarHBondContact O-N 3.33Å; D80-Y82 VanDerWaalsContact C-N 3.31Å; D80-Y82 PolarHBondContact O-N 3.3Å; Y82-Q84 VanDerWaalsContact C-N 3.35Å; Y82-Q84 PolarHBondContact O-N 3.12Å; Y82-L85 PolarHBondContact O-N 3.43Å; Y82-C86 PolarHBondContact O-N 3.27Å; Y82-C86 PolarHBondContact O-SG 3.5Å
83F96.2Very high94.9Very high0 Ų040.2 Ų40.20%022%0.223CC..Hα-helixtrans-64.2-39177.4-71.2-57.4000112.7F46 E49 K50 N56 Y57 L79 D80 L81 C86 S87F46-F83 HydrophobicContact CD2-CB 3.76Å; F46-F83 HydrophobicContact CE2-CB 3.69Å; E49-F83 HydrophobicContact CB-CD1 4.16Å; E49-F83 WeakPolarHBondContact O-CE1 3.33Å; K50-F83 HydrophobicContact CB-CD2 4.33Å; K50-F83 HydrophobicContact CG-CD2 4.29Å; K50-F83 HydrophobicContact CG-CE2 4.42Å; N56-F83 HydrophobicContact CB-CE1 4.31Å; N56-F83 HydrophobicContact CB-CZ 3.98Å; Y57-F83 HydrophobicContact CE2-CE2 4.28Å; Y57-F83 HydrophobicContact CE2-CZ 4.3Å; L79-F83 HydrophobicContact CD2-CD2 4.35Å; L79-F83 HydrophobicContact CD2-CE2 3.5Å; L79-F83 HydrophobicContact CD2-CZ 4.19Å; L79-F83 HydrophobicContact CG-CD2 4.21Å; L79-F83 HydrophobicContact CG-CE2 3.69Å; L79-F83 HydrophobicContact CG-CZ 4.37Å; L79-F83 WeakPolarHBondContact O-CD2 3.33Å; L79-F83 PolarHBondContact O-N 3.3Å; D80-F83 PolarHBondContact O-N 3.07Å; L81-F83 PolarHBondContact O-N 3.28Å; F83-C86 PolarHBondContact O-N 3.28Å; F83-S87 WeakPolarHBondContact O-CB 3.29Å; F83-S87 PolarHBondContact O-N 3.25Å; F83-S87 PolarHBondContact O-OG 3Å
84Q95.8Very high95.4Very high41 Ų4138.4 Ų38.419%0.19221%0.211CC..Hα-helixtrans-60.5-47.3175.4-71.9177.1-46.800111.1F23 F41 F46 D80 L81 Y82 C86 S87F23-Q84 HydrophobicContact CD2-CB 3.84Å; F23-Q84 HydrophobicContact CE2-CB 3.92Å; F41-Q84 HydrophobicContact CE2-CB 4.21Å; F41-Q84 HydrophobicContact CE2-CG 4.48Å; F41-Q84 WeakPolarHBondContact CE2-O 3.42Å; F41-Q84 HydrophobicContact CZ-CG 4.48Å; F46-Q84 HydrophobicContact CD2-CG 3.91Å; F46-Q84 HydrophobicContact CE2-CG 3.56Å; F46-Q84 HydrophobicContact CZ-CG 3.99Å; D80-Q84 WeakPolarHBondContact O-CG 3.3Å; D80-Q84 PolarHBondContact O-N 3.4Å; L81-Q84 PolarHBondContact O-N 2.88Å; Y82-Q84 VanDerWaalsContact C-N 3.35Å; Y82-Q84 PolarHBondContact O-N 3.12Å; Q84-C86 VanDerWaalsContact C-N 3.35Å; Q84-C86 PolarHBondContact O-N 3.35Å; Q84-S87 PolarHBondContact O-N 2.85Å; Q84-S87 VanDerWaalsContact O-N 3.08Å
85L96Very high95.7Very high41 Ų4134.7 Ų34.722%0.21519%0.191CC..Hα-helixtrans-65.8-35.6179.9-66.9179.3000112.7I13 F23 V26 L81 Y82 S87 V88I13-L85 HydrophobicContact CD1-CD1 4.35Å; F23-L85 HydrophobicContact CD2-CD2 4.21Å; F23-L85 HydrophobicContact CE2-CD2 4.39Å; V26-L85 HydrophobicContact CB-CD2 3.85Å; V26-L85 HydrophobicContact CG1-CD1 4.46Å; V26-L85 HydrophobicContact CG1-CD2 3.48Å; V26-L85 VanDerWaalsContact CG1-CD2 3.48Å; V26-L85 HydrophobicContact CG2-CD2 4.29Å; L81-L85 HydrophobicContact CD1-CD1 4.38Å; L81-L85 HydrophobicContact CD1-CG 4.2Å; L81-L85 HydrophobicContact CG-CD1 4.11Å; L81-L85 HydrophobicContact CG-CG 4.33Å; L81-L85 WeakPolarHBondContact O-CB 3.23Å; L81-L85 VanDerWaalsContact O-CG 3.26Å; L81-L85 WeakPolarHBondContact O-CG 3.29Å; L81-L85 PolarHBondContact O-N 3.38Å; Y82-L85 PolarHBondContact O-N 3.43Å; L85-S87 PolarHBondContact O-N 3.4Å; L85-V88 WeakPolarHBondContact O-CG2 3.24Å; L85-V88 PolarHBondContact O-N 3.16Å
86C95.6Very high95.9Very high73 Ų7336.3 Ų36.349%0.49320%0.203SC..Hα-helixtrans-69.9-13.6174.2-690000113.6Y82 F83 Q84Y82-C86 PolarHBondContact O-N 3.27Å; Y82-C86 PolarHBondContact O-SG 3.5Å; F83-C86 PolarHBondContact O-N 3.28Å; Q84-C86 VanDerWaalsContact C-N 3.35Å; Q84-C86 PolarHBondContact O-N 3.35Å
87S96.8Very high96.2Very high4 Ų433.7 Ų33.73%0.02819%0.191CC..THydrogen-bonded Turntrans-104.711.2-178.8-510000113.1S42 F46 F83 Q84 L85S42-S87 PolarHBondContact N-O 3.42Å; F46-S87 WeakPolarHBondContact CA-OG 3.45Å; F46-S87 PolarHBondContact N-OG 2.87Å; F83-S87 WeakPolarHBondContact O-CB 3.29Å; F83-S87 PolarHBondContact O-N 3.25Å; F83-S87 PolarHBondContact O-OG 3Å; Q84-S87 PolarHBondContact O-N 2.85Å; Q84-S87 VanDerWaalsContact O-N 3.08Å; L85-S87 PolarHBondContact O-N 3.4Å
88V96.5Very high96.5Very high31 Ų3133.9 Ų33.919%0.18819%0.188CC..EExtended strand (participates in β ladder)trans-71.8134.7172.2173.50000109.3F23 L27 L30 M39 L85F23-V88 HydrophobicContact CE2-CG2 4.17Å; F23-V88 HydrophobicContact CZ-CG2 4.46Å; L27-V88 HydrophobicContact CD1-CG1 4.46Å; L30-V88 HydrophobicContact CD1-CG1 4.33Å; M39-V88 HydrophobicContact CE-CG1 3.25Å; L85-V88 WeakPolarHBondContact O-CG2 3.24Å; L85-V88 PolarHBondContact O-N 3.16Å
89E96.3Very high96.7Very high82 Ų8233.7 Ų33.738%0.38319%0.187SC..EExtended strand (participates in β ladder)trans-103.8139.8-179.4-64.9-172.5148.100111.1Y38 G40 S42Y38-E89 HydrophobicContact CE1-CB 4.16Å; Y38-E89 PolarHBondContact OH-OE2 3.13Å; G40-E89 PolarHBondContact N-O 3.41Å; G40-E89 PolarHBondContact O-N 2.95Å; S42-E89 WeakPolarHBondContact CB-OE1 3.43Å
90V96.5Very high96.9Very high59 Ų5934.5 Ų34.536%0.35819%0.194SC..EExtended strand (participates in β ladder)trans-138.2154.6175-610000109.6M39 M98 M167M39-V90 HydrophobicContact CE-CG1 3.77Å; M39-V90 HydrophobicContact SD-CG1 3.52Å; M39-V90 VanDerWaalsContact SD-CG1 3.52Å; V90-M98 HydrophobicContact CG1-SD 4.29Å; V90-M167 HydrophobicContact CG2-CE 4.45Å
91T97.5Very high97.1Very high57 Ų5733.5 Ų33.535%0.3519%0.188SC..  trans-89.1168.1167.561.30000110.6Y38 E93 S94 G95Y38-T91 HydrophobicContact CD1-CG2 3.77Å; Y38-T91 HydrophobicContact CE1-CG2 4.45Å; Y38-T91 HydrophobicContact CG-CG2 4.16Å; T91-E93 PolarHBondContact O-N 2.75Å; T91-S94 PolarHBondContact N-OG 3.17Å; T91-S94 PolarHBondContact O-OG 2.85Å; T91-S94 VanDerWaalsContact O-OG 3.1Å; T91-S94 PolarHBondContact OG1-N 3.45Å; T91-S94 PolarHBondContact OG1-OG 3.35Å; T91-G95 PolarHBondContact O-N 2.86Å
92C97.6Very high97.3Very high53 Ų5333.9 Ų33.936%0.35819%0.19SC..Hα-helixtrans-61-34.4172-68.10000112.1S96 M167 L169C92-S96 VanDerWaalsContact O-CB 3.27Å; C92-S96 WeakPolarHBondContact O-CB 3.48Å; C92-S96 PolarHBondContact O-N 3.31Å; C92-S96 PolarHBondContact O-OG 3.46Å; C92-M167 HydrophobicContact CB-CG 4.44Å; C92-M167 WeakPolarHBondContact O-CB 3.18Å; C92-L169 WeakPolarHBondContact SG-CB 3.42Å
93E97.7Very high97.4Very high142 Ų14233.1 Ų33.166%0.66419%0.188SC*.Hα-helixtrans-65.8-59.2179.2-63.4179.8165.600110.2T91 G95 S96 V97T91-E93 PolarHBondContact O-N 2.75Å; E93-G95 VanDerWaalsContact C-N 3.32Å; E93-G95 PolarHBondContact O-N 3.03Å; E93-S96 WeakPolarHBondContact O-CA 3.48Å; E93-S96 WeakPolarHBondContact O-CB 3.09Å; E93-S96 PolarHBondContact O-N 3.16Å; E93-S96 PolarHBondContact O-OG 3.1Å; E93-V97 PolarHBondContact O-N 2.96Å; E93-V97 VanDerWaalsContact O-N 3.11Å
94S97.6Very high97.5Very high0 Ų036.9 Ų36.90%021%0.209CC..Hα-helixtrans-57.3-43.8177.950.10000112.5E37 Y38 T91 S96 V97 M98E37-S94 WeakPolarHBondContact OE2-CA 3.19Å; E37-S94 PolarHBondContact OE2-N 3.04Å; Y38-S94 VanDerWaalsContact O-CB 3.26Å; Y38-S94 WeakPolarHBondContact O-CB 3.15Å; Y38-S94 PolarHBondContact O-OG 3.48Å; T91-S94 PolarHBondContact N-OG 3.17Å; T91-S94 PolarHBondContact O-OG 2.85Å; T91-S94 VanDerWaalsContact O-OG 3.1Å; T91-S94 PolarHBondContact OG1-N 3.45Å; T91-S94 PolarHBondContact OG1-OG 3.35Å; S94-S96 VanDerWaalsContact C-N 3.29Å; S94-S96 PolarHBondContact O-N 3.25Å; S94-V97 PolarHBondContact O-N 3.41Å; S94-M98 WeakPolarHBondContact O-CG 3.45Å; S94-M98 PolarHBondContact O-N 2.88Å
95G97.4Very high97.5Very high0 Ų036.5 Ų36.50%022%0.216CC..Hα-helixtrans-62-34.1175.300000113.5T91 E93 M98 A99 L157T91-G95 PolarHBondContact O-N 2.86Å; E93-G95 VanDerWaalsContact C-N 3.32Å; E93-G95 PolarHBondContact O-N 3.03Å; G95-M98 PolarHBondContact O-N 3.45Å; G95-A99 PolarHBondContact O-N 3.44Å; G95-L157 WeakPolarHBondContact O-CD1 3.46Å
96S98.3Very high97.6Very high38 Ų3834.5 Ų34.527%0.26621%0.205SC..Hα-helixtrans-69-37.9175.776.40000112C92 E93 S94 A99 A100C92-S96 VanDerWaalsContact O-CB 3.27Å; C92-S96 WeakPolarHBondContact O-CB 3.48Å; C92-S96 PolarHBondContact O-N 3.31Å; C92-S96 PolarHBondContact O-OG 3.46Å; E93-S96 WeakPolarHBondContact O-CA 3.48Å; E93-S96 WeakPolarHBondContact O-CB 3.09Å; E93-S96 PolarHBondContact O-N 3.16Å; E93-S96 PolarHBondContact O-OG 3.1Å; S94-S96 VanDerWaalsContact C-N 3.29Å; S94-S96 PolarHBondContact O-N 3.25Å; S96-A99 PolarHBondContact O-N 2.95Å; S96-A100 WeakPolarHBondContact O-CB 3.17Å; S96-A100 PolarHBondContact O-N 3.02Å
97V98.4Very high97.7Very high12 Ų1234.4 Ų34.47%0.07320%0.199CC..Hα-helixtrans-64.7-43.2174.5-176.30000110.4E93 S94 A99 A100 T101 P109 I110E93-V97 PolarHBondContact O-N 2.96Å; E93-V97 VanDerWaalsContact O-N 3.11Å; S94-V97 PolarHBondContact O-N 3.41Å; V97-A99 PolarHBondContact O-N 3.23Å; V97-A100 CarbonylContact O-C 3.5Å; V97-A100 PolarHBondContact O-N 3.27Å; V97-A100 VanDerWaalsContact O-N 3.12Å; V97-T101 PolarHBondContact O-N 3.36Å; V97-T101 PolarHBondContact O-OG1 3.31Å; V97-P109 HydrophobicContact CG1-CG 4.24Å; V97-I110 HydrophobicContact CG1-CD1 3.86Å; V97-I110 HydrophobicContact CG1-CG1 3.97Å; V97-I110 HydrophobicContact CG2-CD1 4.22Å
98M98.1Very high97.7Very high26 Ų2634.2 Ų34.213%0.12820%0.198CC..Hα-helixtrans-60.7-44.2175.5-64.9172.577.100112.3L30 M33 A34 M39 V90 S94 G95 A100 T101 L102L30-M98 HydrophobicContact CB-CE 4.12Å; L30-M98 HydrophobicContact CD2-CE 3.5Å; L30-M98 HydrophobicContact CG-CE 4.31Å; M33-M98 HydrophobicContact CB-CG 4.1Å; A34-M98 HydrophobicContact CB-CG 3.75Å; A34-M98 HydrophobicContact CB-SD 4.31Å; M39-M98 HydrophobicContact SD-SD 4.08Å; V90-M98 HydrophobicContact CG1-SD 4.29Å; S94-M98 WeakPolarHBondContact O-CG 3.45Å; S94-M98 PolarHBondContact O-N 2.88Å; G95-M98 PolarHBondContact O-N 3.45Å; M98-A100 VanDerWaalsContact C-N 3.28Å; M98-A100 PolarHBondContact O-N 2.92Å; M98-T101 WeakPolarHBondContact O-CB 3.36Å; M98-T101 PolarHBondContact O-N 3.42Å; M98-L102 PolarHBondContact O-N 3Å
99A98.4Very high97.8Very high0 Ų035.8 Ų35.80%021%0.209CC..Hα-helixtrans-61.1-39.6174.100000111.6G95 S96 V97 L102 A103 L157 V159G95-A99 PolarHBondContact O-N 3.44Å; S96-A99 PolarHBondContact O-N 2.95Å; V97-A99 PolarHBondContact O-N 3.23Å; A99-L102 WeakPolarHBondContact O-CB 3.15Å; A99-L102 PolarHBondContact O-N 3.28Å; A99-A103 PolarHBondContact O-N 3.5Å; A99-L157 HydrophobicContact CB-CD1 3.69Å; A99-L157 HydrophobicContact CB-CG 4.14Å; A99-V159 HydrophobicContact CB-CG2 4.17Å
100A98.5Very high97.8Very high19 Ų1936.6 Ų36.616%0.15721%0.214CC..Hα-helixtrans-72-32.3-179.100000111.7S96 V97 M98 L102 A103 N104 P109S96-A100 WeakPolarHBondContact O-CB 3.17Å; S96-A100 PolarHBondContact O-N 3.02Å; V97-A100 CarbonylContact O-C 3.5Å; V97-A100 PolarHBondContact O-N 3.27Å; V97-A100 VanDerWaalsContact O-N 3.12Å; M98-A100 VanDerWaalsContact C-N 3.28Å; M98-A100 PolarHBondContact O-N 2.92Å; A100-L102 VanDerWaalsContact C-N 3.28Å; A100-L102 PolarHBondContact O-N 2.97Å; A100-A103 CarbonylContact O-C 3.46Å; A100-A103 WeakPolarHBondContact O-CB 3.43Å; A100-A103 PolarHBondContact O-N 3.4Å; A100-A103 VanDerWaalsContact O-N 3.1Å; A100-N104 VanDerWaalsContact O-CB 3.29Å; A100-N104 WeakPolarHBondContact O-CB 3.49Å; A100-N104 PolarHBondContact O-N 2.84Å; A100-P109 HydrophobicContact CB-CG 3.8Å
101T98.4Very high97.9Very high0 Ų036.8 Ų36.80%022%0.216CC..Hα-helixtrans-59-39.7169.4-61.80000111.5M33 V97 M98 N104 G106 C108 P109M33-T101 HydrophobicContact CB-CG2 4.36Å; M33-T101 HydrophobicContact CG-CG2 4.21Å; M33-T101 PolarHBondContact O-OG1 3.37Å; V97-T101 PolarHBondContact O-N 3.36Å; V97-T101 PolarHBondContact O-OG1 3.31Å; M98-T101 WeakPolarHBondContact O-CB 3.36Å; M98-T101 PolarHBondContact O-N 3.42Å; T101-N104 PolarHBondContact O-N 3.29Å; T101-G106 WeakPolarHBondContact O-CA 3.27Å; T101-G106 PolarHBondContact O-N 3.01Å; T101-C108 HydrophobicContact CG2-CB 4.47Å; T101-C108 WeakPolarHBondContact OG1-CA 3.17Å; T101-P109 VanDerWaalsContact OG1-CD 3.24Å; T101-P109 WeakPolarHBondContact OG1-CD 3.33Å
102L98.4Very high97.8Very high11 Ų1136.8 Ų36.86%0.05823%0.227CC..Hα-helixtrans-69.3-40172-62.4174.8000111.9M33 M98 A99 A100 N104 G105 L116 V121 L125 M128 L157 V159M33-L102 HydrophobicContact CE-CD2 3.93Å; M33-L102 HydrophobicContact CE-CG 4.06Å; M98-L102 PolarHBondContact O-N 3Å; A99-L102 WeakPolarHBondContact O-CB 3.15Å; A99-L102 PolarHBondContact O-N 3.28Å; A100-L102 VanDerWaalsContact C-N 3.28Å; A100-L102 PolarHBondContact O-N 2.97Å; L102-N104 PolarHBondContact O-N 3.47Å; L102-G105 PolarHBondContact O-N 3.45Å; L102-L116 HydrophobicContact CD2-CD1 3.83Å; L102-V121 HydrophobicContact CD2-CG1 4.39Å; L102-V121 HydrophobicContact CD2-CG2 4.24Å; L102-V121 WeakPolarHBondContact O-CG1 3.33Å; L102-L125 HydrophobicContact CB-CD2 4.24Å; L102-M128 HydrophobicContact CD1-SD 4.34Å; L102-L157 HydrophobicContact CD1-CD2 4.41Å; L102-V159 HydrophobicContact CB-CG1 4.42Å; L102-V159 HydrophobicContact CB-CG2 4.24Å; L102-V159 HydrophobicContact CD1-CG2 4.28Å
103A98.3Very high97.8Very high6 Ų637.8 Ų37.85%0.0523%0.227CC..Hα-helixtrans-60.9-32.2175.900000112.4A99 A100 G105 V159 N162 M164A99-A103 PolarHBondContact O-N 3.5Å; A100-A103 CarbonylContact O-C 3.46Å; A100-A103 WeakPolarHBondContact O-CB 3.43Å; A100-A103 PolarHBondContact O-N 3.4Å; A100-A103 VanDerWaalsContact O-N 3.1Å; A103-G105 VanDerWaalsContact C-N 3.34Å; A103-V159 HydrophobicContact CB-CG1 3.77Å; A103-N162 PolarHBondContact O-N 3.09Å; A103-M164 WeakPolarHBondContact CB-O 3.3Å
104N98.3Very high97.8Very high79 Ų7935.3 Ų35.342%0.42223%0.225SC..THydrogen-bonded Turntrans-96.329.4-177.3-165.539.4000112.9A100 T101 L102 G106 I107A100-N104 VanDerWaalsContact O-CB 3.29Å; A100-N104 WeakPolarHBondContact O-CB 3.49Å; A100-N104 PolarHBondContact O-N 2.84Å; T101-N104 PolarHBondContact O-N 3.29Å; L102-N104 PolarHBondContact O-N 3.47Å; N104-G106 PolarHBondContact O-N 3.44Å; N104-G106 VanDerWaalsContact O-N 3.15Å; N104-I107 WeakPolarHBondContact CB-O 3.45Å; N104-I107 PolarHBondContact ND2-O 3.06Å; N104-I107 PolarHBondContact O-N 3.49Å
105G97.3Very high97.7Very high33 Ų3335.9 Ų35.934%0.3423%0.228SC..THydrogen-bonded Turntrans68.417.3171.100000115.5L102 A103L102-G105 PolarHBondContact O-N 3.45Å; A103-G105 VanDerWaalsContact C-N 3.34Å
106G97Very high97.7Very high0 Ų038 Ų380%024%0.239CC..THydrogen-bonded Turntrans1001.8179.600000114.4T101 N104 V115 L116T101-G106 WeakPolarHBondContact O-CA 3.27Å; T101-G106 PolarHBondContact O-N 3.01Å; N104-G106 PolarHBondContact O-N 3.44Å; N104-G106 VanDerWaalsContact O-N 3.15Å; G106-V115 PolarHBondContact O-N 2.72Å; G106-L116 PolarHBondContact O-N 2.96Å; G106-L116 VanDerWaalsContact O-N 3.1Å
107I98.3Very high97.7Very high71 Ų7139.6 Ų39.636%0.36425%0.25SS..BIsolated β-bridgetrans-96.4124.4175.1-57.2171.9000108.7N104 E113N104-I107 WeakPolarHBondContact CB-O 3.45Å; N104-I107 PolarHBondContact ND2-O 3.06Å; N104-I107 PolarHBondContact O-N 3.49Å; I107-E113 CarbonylContact C-O 3.58Å; I107-E113 WeakPolarHBondContact CA-O 3.47Å
108C97.9Very high97.7Very high0 Ų042.3 Ų42.30%028%0.275CS..  trans-64.7127.2179.7179.90000110.3T101 I110 T111 G112 E113 V115T101-C108 HydrophobicContact CG2-CB 4.47Å; T101-C108 WeakPolarHBondContact OG1-CA 3.17Å; C108-I110 VanDerWaalsContact C-N 3.33Å; C108-I110 PolarHBondContact O-N 3.32Å; C108-T111 VanDerWaalsContact CB-OG1 3.23Å; C108-T111 WeakPolarHBondContact CB-OG1 3.43Å; C108-T111 PolarHBondContact SG-OG1 3.21Å; C108-G112 WeakPolarHBondContact O-CA 3.5Å; C108-G112 PolarHBondContact O-N 2.83Å; C108-E113 PolarHBondContact N-O 2.92Å; C108-V115 HydrophobicContact CB-CG2 4.14Å
109P97.6Very high97.7Very high63 Ų6346.8 Ų46.841%0.40930%0.295SS..THydrogen-bonded Turntrans-71-26.9-170.928.7-36.7000113.4V97 A100 T101V97-P109 HydrophobicContact CG1-CG 4.24Å; A100-P109 HydrophobicContact CB-CG 3.8Å; T101-P109 VanDerWaalsContact OG1-CD 3.24Å; T101-P109 WeakPolarHBondContact OG1-CD 3.33Å
110I97.3Very high97.7Very high99 Ų9948.6 Ų48.651%0.50831%0.31SS..THydrogen-bonded Turntrans-96.4-20.5-177.263.9175.4000113.4V97 C108V97-I110 HydrophobicContact CG1-CD1 3.86Å; V97-I110 HydrophobicContact CG1-CG1 3.97Å; V97-I110 HydrophobicContact CG2-CD1 4.22Å; C108-I110 VanDerWaalsContact C-N 3.33Å; C108-I110 PolarHBondContact O-N 3.32Å
111T97.1Very high97.6Very high64 Ų6447.9 Ų47.939%0.39330%0.304SS..THydrogen-bonded Turntrans-109.6-22.9178.568.70000113.9C108 E113C108-T111 VanDerWaalsContact CB-OG1 3.23Å; C108-T111 WeakPolarHBondContact CB-OG1 3.43Å; C108-T111 PolarHBondContact SG-OG1 3.21Å; T111-E113 PolarHBondContact O-N 3.48Å; T111-E113 PolarHBondContact OG1-N 3.24Å
112G96.2Very high97.6Very high56 Ų5655.2 Ų55.258%0.57733%0.331SS*.  trans73.94.2-172.900000114.6C108C108-G112 WeakPolarHBondContact O-CA 3.5Å; C108-G112 PolarHBondContact O-N 2.83Å
113E97.2Very high97.6Very high75 Ų7557.9 Ų57.935%0.3535%0.346SS..  trans-72.7133.9178.9-170.5-179.1172.500111.1K32 I107 C108 T111 V115K32-E113 WeakPolarHBondContact CD-OE1 3.34Å; K32-E113 WeakPolarHBondContact CE-OE1 3.43Å; K32-E113 IonicContact NZ-OE1 2.72Å; K32-E113 PolarHBondContact NZ-OE1 3.49Å; I107-E113 CarbonylContact C-O 3.58Å; I107-E113 WeakPolarHBondContact CA-O 3.47Å; C108-E113 PolarHBondContact N-O 2.92Å; T111-E113 PolarHBondContact O-N 3.48Å; T111-E113 PolarHBondContact OG1-N 3.24Å; E113-V115 HydrophobicContact CB-CG2 4.4Å; E113-V115 HydrophobicContact CG-CG2 4.46Å; E113-V115 WeakPolarHBondContact O-CG2 2.99Å; E113-V115 PolarHBondContact O-N 3.01Å
114S96.9Very high97.6Very high90 Ų9060.1 Ų60.163%0.62936%0.359SS*.BIsolated β-bridgetrans-77.298.1170.3175.80000110
115V97.1Very high97.6Very high12 Ų1257.4 Ų57.47%0.07334%0.344CS..  trans-90.2-41.5-174.2-170.40000112.1Y29 K32 M33 G106 C108 E113Y29-V115 HydrophobicContact CD1-CG1 3.97Å; Y29-V115 HydrophobicContact CE1-CG1 4.44Å; Y29-V115 WeakPolarHBondContact CE1-O 3.43Å; K32-V115 HydrophobicContact CB-CB 4.49Å; K32-V115 HydrophobicContact CB-CG1 3.75Å; K32-V115 HydrophobicContact CB-CG2 3.88Å; M33-V115 HydrophobicContact CG-CB 4.31Å; M33-V115 HydrophobicContact CG-CG1 3.66Å; G106-V115 PolarHBondContact O-N 2.72Å; C108-V115 HydrophobicContact CB-CG2 4.14Å; E113-V115 HydrophobicContact CB-CG2 4.4Å; E113-V115 HydrophobicContact CG-CG2 4.46Å; E113-V115 WeakPolarHBondContact O-CG2 2.99Å; E113-V115 PolarHBondContact O-N 3.01Å
116L97.4Very high97.7Very high43 Ų4359.3 Ų59.323%0.22535%0.352CS..SBendtrans-124.1151.6-176.4-62.2175.4000111Y29 M33 L102 G106 V121Y29-L116 HydrophobicContact CD1-CD2 4.28Å; Y29-L116 HydrophobicContact CE1-CD2 4.49Å; M33-L116 HydrophobicContact CE-CD1 3.76Å; M33-L116 HydrophobicContact SD-CD1 3.81Å; M33-L116 HydrophobicContact SD-CG 4.34Å; L102-L116 HydrophobicContact CD2-CD1 3.83Å; G106-L116 PolarHBondContact O-N 2.96Å; G106-L116 VanDerWaalsContact O-N 3.1Å; L116-V121 HydrophobicContact CB-CG2 3.76Å; L116-V121 HydrophobicContact CD1-CG2 4.1Å
117S98.1Very high97.7Very high72 Ų7263.7 Ų63.750%0.50338%0.375SS..  trans-70.8143.3170.670.10000110.7E119 A120 V121S117-E119 PolarHBondContact O-N 3.22Å; S117-E119 VanDerWaalsContact O-N 3.16Å; S117-A120 PolarHBondContact O-N 3.12Å; S117-A120 WeakPolarHBondContact OG-CB 3.26Å; S117-A120 PolarHBondContact OG-N 2.83Å; S117-V121 WeakPolarHBondContact O-CG2 3.5Å; S117-V121 PolarHBondContact O-N 3.1Å; S117-V121 VanDerWaalsContact O-N 3.08Å
118A97Very high97.7Very high70 Ų7060.6 Ų60.658%0.57936%0.359SS*.Hα-helixtrans-57.8-31.4178.200000112.7V121 R122A118-V121 PolarHBondContact O-N 3.38Å; A118-R122 WeakPolarHBondContact O-CB 3.42Å; A118-R122 PolarHBondContact O-N 3.37Å
119E98.4Very high97.7Very high119 Ų11962.3 Ų62.356%0.55637%0.367SS*.Hα-helixtrans-63.7-48.9173.9-178.2-179.5-17700112S117 V121 R122 N123S117-E119 PolarHBondContact O-N 3.22Å; S117-E119 VanDerWaalsContact O-N 3.16Å; E119-V121 VanDerWaalsContact C-N 3.26Å; E119-V121 PolarHBondContact O-N 2.82Å; E119-R122 PolarHBondContact O-N 2.93Å; E119-N123 WeakPolarHBondContact O-CB 3.36Å; E119-N123 PolarHBondContact O-N 3.34Å; E119-N123 PolarHBondContact O-ND2 2.9Å; E119-N123 PolarHBondContact O-OD1 3.45Å
120A98.1Very high97.7Very high38 Ų3862.2 Ų62.231%0.31437%0.368SS..Hα-helixtrans-61.3-39.817900000111S117 T124S117-A120 PolarHBondContact O-N 3.12Å; S117-A120 WeakPolarHBondContact OG-CB 3.26Å; S117-A120 PolarHBondContact OG-N 2.83Å; A120-T124 VanDerWaalsContact O-CB 3.3Å; A120-T124 WeakPolarHBondContact O-CB 3.11Å; A120-T124 PolarHBondContact O-N 3.11Å; A120-T124 PolarHBondContact O-OG1 3.21Å
121V98.4Very high97.6Very high4 Ų460.2 Ų60.22%0.02436%0.363CS..Hα-helixtrans-64-50.7177.5175.10000111L102 L116 S117 A118 E119 N123 T124 L125L102-V121 HydrophobicContact CD2-CG1 4.39Å; L102-V121 HydrophobicContact CD2-CG2 4.24Å; L102-V121 WeakPolarHBondContact O-CG1 3.33Å; L116-V121 HydrophobicContact CB-CG2 3.76Å; L116-V121 HydrophobicContact CD1-CG2 4.1Å; S117-V121 WeakPolarHBondContact O-CG2 3.5Å; S117-V121 PolarHBondContact O-N 3.1Å; S117-V121 VanDerWaalsContact O-N 3.08Å; A118-V121 PolarHBondContact O-N 3.38Å; E119-V121 VanDerWaalsContact C-N 3.26Å; E119-V121 PolarHBondContact O-N 2.82Å; V121-N123 VanDerWaalsContact C-N 3.35Å; V121-N123 PolarHBondContact O-N 2.89Å; V121-T124 PolarHBondContact O-N 3.17Å; V121-L125 HydrophobicContact CG1-CD1 3.91Å; V121-L125 HydrophobicContact CG1-CG 4.34Å; V121-L125 WeakPolarHBondContact O-CG 3.39Å; V121-L125 PolarHBondContact O-N 3.03Å
122R98.3Very high97.5Very high154 Ų15457.2 Ų57.258%0.58134%0.344SS*.Hα-helixtrans-55.3-50.3176.6-180-175.965.1-162.7-3.2111.4A118 E119 T124 L125 S126A118-R122 WeakPolarHBondContact O-CB 3.42Å; A118-R122 PolarHBondContact O-N 3.37Å; E119-R122 PolarHBondContact O-N 2.93Å; R122-T124 VanDerWaalsContact C-N 3.29Å; R122-T124 PolarHBondContact O-N 2.91Å; R122-L125 PolarHBondContact O-N 3.24Å; R122-S126 PolarHBondContact O-N 3.2Å; R122-S126 PolarHBondContact O-OG 3.19Å; R122-S126 VanDerWaalsContact O-OG 3.1Å
123N98.5Very high97.4Very high68 Ų6854.6 Ų54.636%0.36432%0.317SS..Hα-helixtrans-61.6-40.6-178.5-64.4-7.9000111.1E119 V121 L127E119-N123 WeakPolarHBondContact O-CB 3.36Å; E119-N123 PolarHBondContact O-N 3.34Å; E119-N123 PolarHBondContact O-ND2 2.9Å; E119-N123 PolarHBondContact O-OD1 3.45Å; V121-N123 VanDerWaalsContact C-N 3.35Å; V121-N123 PolarHBondContact O-N 2.89Å; N123-L127 WeakPolarHBondContact O-CG 3.32Å; N123-L127 PolarHBondContact O-N 3.01Å; N123-L127 VanDerWaalsContact O-N 3.12Å
124T98.4Very high97.3Very high53 Ų5354.7 Ų54.733%0.32531%0.314SS..Hα-helixtrans-64-48.4177.1-59.60000111.6A120 V121 R122 S126 L127 M128A120-T124 VanDerWaalsContact O-CB 3.3Å; A120-T124 WeakPolarHBondContact O-CB 3.11Å; A120-T124 PolarHBondContact O-N 3.11Å; A120-T124 PolarHBondContact O-OG1 3.21Å; V121-T124 PolarHBondContact O-N 3.17Å; R122-T124 VanDerWaalsContact C-N 3.29Å; R122-T124 PolarHBondContact O-N 2.91Å; T124-S126 PolarHBondContact O-N 2.95Å; T124-L127 PolarHBondContact O-N 3.41Å; T124-M128 HydrophobicContact CG2-CG 4.33Å; T124-M128 HydrophobicContact CG2-SD 3.94Å; T124-M128 WeakPolarHBondContact O-CB 3.44Å; T124-M128 VanDerWaalsContact O-CG 3.3Å; T124-M128 WeakPolarHBondContact O-CG 3.39Å; T124-M128 PolarHBondContact O-N 2.89Å
125L98.3Very high97.2Very high21 Ų2157.4 Ų57.411%0.1132%0.322CS..Hα-helixtrans-63.3-39.8-179.9-68176.3000112.3L102 V121 R122 L127 M128 H129 P147 V159 P161L102-L125 HydrophobicContact CB-CD2 4.24Å; V121-L125 HydrophobicContact CG1-CD1 3.91Å; V121-L125 HydrophobicContact CG1-CG 4.34Å; V121-L125 WeakPolarHBondContact O-CG 3.39Å; V121-L125 PolarHBondContact O-N 3.03Å; R122-L125 PolarHBondContact O-N 3.24Å; L125-L127 PolarHBondContact O-N 3.35Å; L125-M128 HydrophobicContact CD2-SD 4.16Å; L125-M128 PolarHBondContact O-N 3.02Å; L125-H129 PolarHBondContact O-N 3.47Å; L125-P147 HydrophobicContact CB-CB 4.4Å; L125-P147 HydrophobicContact CB-CG 4.31Å; L125-P147 HydrophobicContact CD2-CB 3.93Å; L125-P147 HydrophobicContact CD2-CG 4.28Å; L125-V159 HydrophobicContact CD2-CB 3.82Å; L125-V159 HydrophobicContact CD2-CG1 3.68Å; L125-V159 HydrophobicContact CD2-CG2 3.94Å; L125-P161 HydrophobicContact CD1-CG 4.35Å
126S97.9Very high97.1Very high74 Ų7458 Ų5852%0.51732%0.323SS..Hα-helixtrans-61.3-43.7174.5-60.50000111.9R122 T124 H129 S130R122-S126 PolarHBondContact O-N 3.2Å; R122-S126 PolarHBondContact O-OG 3.19Å; R122-S126 VanDerWaalsContact O-OG 3.1Å; T124-S126 PolarHBondContact O-N 2.95Å; S126-H129 WeakPolarHBondContact O-CB 3.42Å; S126-H129 PolarHBondContact O-N 2.95Å; S126-S130 PolarHBondContact O-N 2.89Å; S126-S130 PolarHBondContact O-OG 3.09Å
127L98.1Very high97Very high92 Ų9256.2 Ų56.248%0.48232%0.315SS..Hα-helixtrans-70.9-32.1177.4-69.2173.8000112.9M1 N123 T124 L125 H129 C131M1-L127 HydrophobicContact CE-CB 3.73Å; M1-L127 HydrophobicContact CG-CB 4.41Å; N123-L127 WeakPolarHBondContact O-CG 3.32Å; N123-L127 PolarHBondContact O-N 3.01Å; N123-L127 VanDerWaalsContact O-N 3.12Å; T124-L127 PolarHBondContact O-N 3.41Å; L125-L127 PolarHBondContact O-N 3.35Å; L127-H129 VanDerWaalsContact C-N 3.33Å; L127-C131 WeakPolarHBondContact O-CA 3.39Å; L127-C131 WeakPolarHBondContact O-CB 3.42Å; L127-C131 PolarHBondContact O-N 2.94Å
128M98Very high96.9Very high6 Ų655.3 Ų55.33%0.0332%0.317CS..Hα-helixtrans-64.5-40.9172.5-75.817468.700110.7M1 L102 T124 L125 G132 P147 K149 L157 V159M1-M128 HydrophobicContact CE-CB 4.44Å; M1-M128 HydrophobicContact CE-CG 3.6Å; L102-M128 HydrophobicContact CD1-SD 4.34Å; T124-M128 HydrophobicContact CG2-CG 4.33Å; T124-M128 HydrophobicContact CG2-SD 3.94Å; T124-M128 WeakPolarHBondContact O-CB 3.44Å; T124-M128 VanDerWaalsContact O-CG 3.3Å; T124-M128 WeakPolarHBondContact O-CG 3.39Å; T124-M128 PolarHBondContact O-N 2.89Å; L125-M128 HydrophobicContact CD2-SD 4.16Å; L125-M128 PolarHBondContact O-N 3.02Å; M128-G132 VanDerWaalsContact O-CA 3.31Å; M128-G132 WeakPolarHBondContact O-CA 3Å; M128-G132 PolarHBondContact O-N 2.83Å; M128-P147 HydrophobicContact CB-CB 3.89Å; M128-K149 HydrophobicContact CE-CB 4.27Å; M128-L157 HydrophobicContact CE-CD2 4.12Å; M128-V159 HydrophobicContact CE-CG2 3.98Å
129H97.6Very high96.8Very high35 Ų3557.4 Ų57.416%0.16231%0.314CS..Hα-helixtrans-61.4-48.7177.4-177.674.8000111.9L125 S126 L127 A141L125-H129 PolarHBondContact O-N 3.47Å; S126-H129 WeakPolarHBondContact O-CB 3.42Å; S126-H129 PolarHBondContact O-N 2.95Å; L127-H129 VanDerWaalsContact C-N 3.33Å; H129-A141 WeakPolarHBondContact O-CB 3.25Å
130S96.7Very high96.8Very high62 Ų6251.9 Ų51.943%0.43429%0.289SS..Hα-helixtrans-86.3-25.2-174.961.50000114.9S126 S137S126-S130 PolarHBondContact O-N 2.89Å; S126-S130 PolarHBondContact O-OG 3.09Å; S130-S137 VanDerWaalsContact O-CB 3.25Å; S130-S137 WeakPolarHBondContact O-CB 3.31Å
131C96.4Very high96.7Very high57 Ų5750.7 Ų50.739%0.38528%0.279SS..Hα-helixtrans-134.711.2-167.4-52.60000114.3M1 L127M1-C131 HydrophobicContact CB-CB 3.77Å; M1-C131 WeakPolarHBondContact CB-O 3.12Å; M1-C131 HydrophobicContact CG-CB 3.85Å; L127-C131 WeakPolarHBondContact O-CA 3.39Å; L127-C131 WeakPolarHBondContact O-CB 3.42Å; L127-C131 PolarHBondContact O-N 2.94Å
132G94.1Very high96.7Very high0 Ų057.8 Ų57.80%031%0.31CS..SBendtrans-82.8-24.8-167.200000117.3M128 S137 A148 K149 S150M128-G132 VanDerWaalsContact O-CA 3.31Å; M128-G132 WeakPolarHBondContact O-CA 3Å; M128-G132 PolarHBondContact O-N 2.83Å; G132-S137 PolarHBondContact N-OG 2.62Å; G132-A148 VanDerWaalsContact CA-O 3.23Å; G132-A148 WeakPolarHBondContact CA-O 3.27Å; G132-K149 WeakPolarHBondContact O-CA 3.43Å; G132-K149 VanDerWaalsContact O-CD 3.27Å; G132-K149 WeakPolarHBondContact O-CD 3.5Å; G132-K149 WeakPolarHBondContact O-CE 3.26Å; G132-K149 PolarHBondContact O-NZ 3.1Å; G132-S150 PolarHBondContact O-N 3.29Å
133M95.6Very high96.5Very high1 Ų155.9 Ų55.91%0.00531%0.307CS..SBendtrans-116.440.2-167.3-57-60.8-70.700112.8F136 S137 F140 A148 S150 I156 N178 T183M133-F136 HydrophobicContact CB-CB 4.47Å; M133-F136 WeakPolarHBondContact O-CA 3.29Å; M133-F136 VanDerWaalsContact O-CB 3.3Å; M133-F136 WeakPolarHBondContact O-CB 3.23Å; M133-F136 PolarHBondContact O-N 2.92Å; M133-F136 VanDerWaalsContact O-N 3.1Å; M133-S137 PolarHBondContact N-OG 3.41Å; M133-S137 PolarHBondContact O-N 3.33Å; M133-F140 HydrophobicContact CB-CB 4.34Å; M133-F140 HydrophobicContact CB-CG 4.48Å; M133-F140 HydrophobicContact CE-CD2 4.4Å; M133-F140 HydrophobicContact CE-CE2 4.27Å; M133-F140 HydrophobicContact CG-CB 4.18Å; M133-F140 HydrophobicContact CG-CD1 3.9Å; M133-F140 HydrophobicContact CG-CD2 4.21Å; M133-F140 HydrophobicContact CG-CE1 4.33Å; M133-F140 HydrophobicContact CG-CG 3.83Å; M133-A148 HydrophobicContact CG-CB 4.19Å; M133-A148 HydrophobicContact SD-CB 3.64Å; M133-S150 PolarHBondContact SD-N 2.86Å; M133-S150 VanDerWaalsContact SD-N 3.36Å; M133-I156 HydrophobicContact CE-CD1 3.8Å; M133-I156 HydrophobicContact CE-CG1 4.15Å; M133-I156 HydrophobicContact CE-CG2 4.02Å; M133-I156 HydrophobicContact SD-CG2 4.31Å; M133-N178 PolarHBondContact O-ND2 3.2Å; M133-N178 VanDerWaalsContact O-ND2 3.16Å; M133-T183 HydrophobicContact CE-CG2 4.22Å
134Y94.8Very high96.5Very high78 Ų7852.7 Ų52.731%0.30629%0.29SS..G310 helixtrans53.8-140.6-174.5-53.1-66.1000111.4F136 S137 L176 G177 N178Y134-F136 PolarHBondContact O-N 3.36Å; Y134-S137 PolarHBondContact N-OG 3.06Å; Y134-S137 WeakPolarHBondContact O-CB 3.3Å; Y134-S137 PolarHBondContact O-N 2.87Å; Y134-S137 PolarHBondContact O-OG 2.84Å; Y134-L176 WeakPolarHBondContact CD2-O 3.45Å; Y134-G177 VanDerWaalsContact CE2-O 3.3Å; Y134-G177 WeakPolarHBondContact CE2-O 3.24Å; Y134-N178 VanDerWaalsContact CD2-OD1 3.28Å; Y134-N178 WeakPolarHBondContact CD2-OD1 3.45Å
135D94.7Very high96.4Very high146 Ų14650.1 Ų50.178%0.78127%0.274SS*.G310 helixtrans-66.6-16.8179-62.1-15.8000112.4S137D135-S137 VanDerWaalsContact C-N 3.25Å; D135-S137 PolarHBondContact O-N 2.84Å
136F95Very high96.4Very high24 Ų2449.2 Ų49.211%0.10527%0.27CS..G310 helixtrans-78.3-4.9173.9-163-119.4000113.3M133 Y134 G138 Q139 F140 L176 N178M133-F136 HydrophobicContact CB-CB 4.47Å; M133-F136 WeakPolarHBondContact O-CA 3.29Å; M133-F136 VanDerWaalsContact O-CB 3.3Å; M133-F136 WeakPolarHBondContact O-CB 3.23Å; M133-F136 PolarHBondContact O-N 2.92Å; M133-F136 VanDerWaalsContact O-N 3.1Å; Y134-F136 PolarHBondContact O-N 3.36Å; F136-G138 VanDerWaalsContact C-N 3.33Å; F136-G138 PolarHBondContact O-N 3.16Å; F136-Q139 HydrophobicContact CD2-CB 3.86Å; F136-Q139 HydrophobicContact CE2-CB 3.7Å; F136-Q139 HydrophobicContact CZ-CB 4.28Å; F136-Q139 PolarHBondContact O-N 3.1Å; F136-F140 HydrophobicContact CD1-CB 3.85Å; F136-F140 HydrophobicContact CD1-CD2 4.1Å; F136-F140 HydrophobicContact CD1-CG 4.46Å; F136-F140 HydrophobicContact CE1-CB 4.03Å; F136-F140 AromaticContact CE1-CD2 3.88Å; F136-F140 HydrophobicContact CE1-CD2 3.88Å; F136-F140 HydrophobicContact CE1-CG 4.47Å; F136-F140 VanDerWaalsContact O-CB 3.29Å; F136-F140 WeakPolarHBondContact O-CB 3.3Å; F136-F140 PolarHBondContact O-N 3.26Å; F136-L176 HydrophobicContact CB-CD1 3.93Å; F136-L176 HydrophobicContact CD2-CD1 4.03Å; F136-L176 HydrophobicContact CG-CD1 4.35Å; F136-N178 VanDerWaalsContact CB-ND2 3.34Å; F136-N178 WeakPolarHBondContact CB-ND2 3.27Å
137S95.4Very high96.4Very high7 Ų746.1 Ų46.15%0.04925%0.248CC..Hα-helixtrans-55.3-43.4-174.9-57.50000113.3S130 G132 M133 Y134 D135 F140 A141S130-S137 VanDerWaalsContact O-CB 3.25Å; S130-S137 WeakPolarHBondContact O-CB 3.31Å; G132-S137 PolarHBondContact N-OG 2.62Å; M133-S137 PolarHBondContact N-OG 3.41Å; M133-S137 PolarHBondContact O-N 3.33Å; Y134-S137 PolarHBondContact N-OG 3.06Å; Y134-S137 WeakPolarHBondContact O-CB 3.3Å; Y134-S137 PolarHBondContact O-N 2.87Å; Y134-S137 PolarHBondContact O-OG 2.84Å; D135-S137 VanDerWaalsContact C-N 3.25Å; D135-S137 PolarHBondContact O-N 2.84Å; S137-F140 PolarHBondContact O-N 3.25Å; S137-A141 VanDerWaalsContact O-CB 3.24Å; S137-A141 WeakPolarHBondContact O-CB 3.32Å; S137-A141 PolarHBondContact O-N 3.05Å
138G95.6Very high96.4Very high53 Ų5341.7 Ų41.755%0.54623%0.225SC..Hα-helixtrans-66.3-44.418000000113.1F136 A141 F142F136-G138 VanDerWaalsContact C-N 3.33Å; F136-G138 PolarHBondContact O-N 3.16Å; G138-A141 PolarHBondContact O-N 3.19Å; G138-F142 WeakPolarHBondContact O-CB 3.39Å; G138-F142 PolarHBondContact O-N 2.62Å; G138-F142 VanDerWaalsContact O-N 3.07Å
139Q95.7Very high96.4Very high113 Ų11343.8 Ų43.853%0.52823%0.234SC..Hα-helixtrans-68.7-38.5177.4-68.2-177.11.200111.5F136 F142 H143F136-Q139 HydrophobicContact CD2-CB 3.86Å; F136-Q139 HydrophobicContact CE2-CB 3.7Å; F136-Q139 HydrophobicContact CZ-CB 4.28Å; F136-Q139 PolarHBondContact O-N 3.1Å; Q139-F142 PolarHBondContact O-N 3.29Å; Q139-H143 WeakPolarHBondContact O-CB 3.47Å; Q139-H143 PolarHBondContact O-CD2 3.44Å; Q139-H143 VanDerWaalsContact O-CD2 3.26Å; Q139-H143 PolarHBondContact O-N 2.94Å
140F97.1Very high96.3Very high3 Ų342.3 Ų42.31%0.01323%0.227CC..Hα-helixtrans-64-45.7175.5-168.5-90.7000111.5M133 F136 S137 F142 V144 G145 L146 A148 L158 C186M133-F140 HydrophobicContact CB-CB 4.34Å; M133-F140 HydrophobicContact CB-CG 4.48Å; M133-F140 HydrophobicContact CE-CD2 4.4Å; M133-F140 HydrophobicContact CE-CE2 4.27Å; M133-F140 HydrophobicContact CG-CB 4.18Å; M133-F140 HydrophobicContact CG-CD1 3.9Å; M133-F140 HydrophobicContact CG-CD2 4.21Å; M133-F140 HydrophobicContact CG-CE1 4.33Å; M133-F140 HydrophobicContact CG-CG 3.83Å; F136-F140 HydrophobicContact CD1-CB 3.85Å; F136-F140 HydrophobicContact CD1-CD2 4.1Å; F136-F140 HydrophobicContact CD1-CG 4.46Å; F136-F140 HydrophobicContact CE1-CB 4.03Å; F136-F140 AromaticContact CE1-CD2 3.88Å; F136-F140 HydrophobicContact CE1-CD2 3.88Å; F136-F140 HydrophobicContact CE1-CG 4.47Å; F136-F140 VanDerWaalsContact O-CB 3.29Å; F136-F140 WeakPolarHBondContact O-CB 3.3Å; F136-F140 PolarHBondContact O-N 3.26Å; S137-F140 PolarHBondContact O-N 3.25Å; F140-F142 PolarHBondContact O-N 3.48Å; F140-V144 HydrophobicContact CD1-CB 4.24Å; F140-V144 HydrophobicContact CD2-CB 4.25Å; F140-V144 HydrophobicContact CD2-CG2 3.87Å; F140-V144 HydrophobicContact CE1-CB 4.05Å; F140-V144 HydrophobicContact CE1-CG1 4Å; F140-V144 HydrophobicContact CE2-CB 4.08Å; F140-V144 HydrophobicContact CE2-CG1 4.16Å; F140-V144 HydrophobicContact CE2-CG2 3.78Å; F140-V144 HydrophobicContact CG-CB 4.34Å; F140-V144 HydrophobicContact CG-CG2 4.36Å; F140-V144 HydrophobicContact CZ-CB 3.98Å; F140-V144 HydrophobicContact CZ-CG1 3.72Å; F140-V144 HydrophobicContact CZ-CG2 4.18Å; F140-V144 WeakPolarHBondContact O-CA 3.47Å; F140-V144 WeakPolarHBondContact O-CB 3.28Å; F140-V144 PolarHBondContact O-N 3.41Å; F140-G145 PolarHBondContact O-N 2.85Å; F140-L146 VanDerWaalsContact CE1-O 3.29Å; F140-L146 WeakPolarHBondContact CE1-O 3.48Å; F140-A148 HydrophobicContact CD1-CB 4.35Å; F140-A148 HydrophobicContact CE1-CB 3.49Å; F140-A148 VanDerWaalsContact CE1-CB 3.49Å; F140-A148 HydrophobicContact CZ-CB 3.77Å; F140-L158 HydrophobicContact CE1-CD1 4.5Å; F140-L158 HydrophobicContact CZ-CD1 4.18Å; F140-C186 HydrophobicContact CE2-CB 3.85Å; F140-C186 HydrophobicContact CZ-CB 3.99Å
141A97.1Very high96.3Very high13 Ų1341 Ų4111%0.10722%0.22CC..Hα-helixtrans-60.7-34.1175.700000112.6H129 S137 G138 G145H129-A141 WeakPolarHBondContact O-CB 3.25Å; S137-A141 VanDerWaalsContact O-CB 3.24Å; S137-A141 WeakPolarHBondContact O-CB 3.32Å; S137-A141 PolarHBondContact O-N 3.05Å; G138-A141 PolarHBondContact O-N 3.19Å; A141-G145 WeakPolarHBondContact O-CA 3.46Å; A141-G145 PolarHBondContact O-N 3.47Å
142F96.7Very high96.2Very high154 Ų15443 Ų4368%0.67523%0.23SC*.Hα-helixtrans-80.2-42.5179.7-176.2-98.6000113.7G138 Q139 F140 H196G138-F142 WeakPolarHBondContact O-CB 3.39Å; G138-F142 PolarHBondContact O-N 2.62Å; G138-F142 VanDerWaalsContact O-N 3.07Å; Q139-F142 PolarHBondContact O-N 3.29Å; F140-F142 PolarHBondContact O-N 3.48Å; F142-H196 PolarHBondContact O-NE2 3.07Å
143H95.4Very high96.2Very high114 Ų11446.4 Ų46.453%0.52825%0.254SS..Hα-helixtrans-90.9-36-174.6-70.7-63.1000113.9Q139Q139-H143 WeakPolarHBondContact O-CB 3.47Å; Q139-H143 PolarHBondContact O-CD2 3.44Å; Q139-H143 VanDerWaalsContact O-CD2 3.26Å; Q139-H143 PolarHBondContact O-N 2.94Å
144V97Very high96.2Very high0 Ų046.4 Ų46.40%025%0.254CS..THydrogen-bonded Turntrans-102.2-39.3-178.8-1760000110.4F140 L146 C186 Q187 V190 H196F140-V144 HydrophobicContact CD1-CB 4.24Å; F140-V144 HydrophobicContact CD2-CB 4.25Å; F140-V144 HydrophobicContact CD2-CG2 3.87Å; F140-V144 HydrophobicContact CE1-CB 4.05Å; F140-V144 HydrophobicContact CE1-CG1 4Å; F140-V144 HydrophobicContact CE2-CB 4.08Å; F140-V144 HydrophobicContact CE2-CG1 4.16Å; F140-V144 HydrophobicContact CE2-CG2 3.78Å; F140-V144 HydrophobicContact CG-CB 4.34Å; F140-V144 HydrophobicContact CG-CG2 4.36Å; F140-V144 HydrophobicContact CZ-CB 3.98Å; F140-V144 HydrophobicContact CZ-CG1 3.72Å; F140-V144 HydrophobicContact CZ-CG2 4.18Å; F140-V144 WeakPolarHBondContact O-CA 3.47Å; F140-V144 WeakPolarHBondContact O-CB 3.28Å; F140-V144 PolarHBondContact O-N 3.41Å; V144-L146 HydrophobicContact CG1-CB 4.12Å; V144-L146 HydrophobicContact CG1-CD1 4.09Å; V144-L146 HydrophobicContact CG1-CG 4.18Å; V144-L146 PolarHBondContact O-N 3.38Å; V144-C186 HydrophobicContact CG1-CB 4.06Å; V144-C186 HydrophobicContact CG2-CB 4.4Å; V144-Q187 HydrophobicContact CG2-CG 3.85Å; V144-V190 HydrophobicContact CG1-CG2 3.79Å; V144-H196 PolarHBondContact O-CD2 3.04Å
145G97.1Very high96.3Very high0 Ų043.4 Ų43.40%025%0.245CC..  trans719.4174.600000115.2F140 A141 H196 N197F140-G145 PolarHBondContact O-N 2.85Å; A141-G145 WeakPolarHBondContact O-CA 3.46Å; A141-G145 PolarHBondContact O-N 3.47Å; G145-H196 WeakPolarHBondContact CA-NE2 3.3Å; G145-N197 WeakPolarHBondContact O-CB 3.33Å; G145-N197 PolarHBondContact O-N 3.49Å
146L97.9Very high96.4Very high2 Ų236.4 Ų36.41%0.0121%0.208CC..  trans-102.6143.6-179.3-69.1174000111.5F140 V144 A148 L158 V160 L189 V190 F195F140-L146 VanDerWaalsContact CE1-O 3.29Å; F140-L146 WeakPolarHBondContact CE1-O 3.48Å; V144-L146 HydrophobicContact CG1-CB 4.12Å; V144-L146 HydrophobicContact CG1-CD1 4.09Å; V144-L146 HydrophobicContact CG1-CG 4.18Å; V144-L146 PolarHBondContact O-N 3.38Å; L146-A148 PolarHBondContact O-N 2.86Å; L146-L158 HydrophobicContact CB-CD1 3.69Å; L146-L158 HydrophobicContact CD1-CD1 3.99Å; L146-L158 HydrophobicContact CD1-CD2 4.24Å; L146-L158 HydrophobicContact CD1-CG 4.36Å; L146-V160 HydrophobicContact CD1-CG2 4.06Å; L146-V160 HydrophobicContact CD2-CB 4.42Å; L146-V160 HydrophobicContact CD2-CG1 4.27Å; L146-V160 HydrophobicContact CD2-CG2 4Å; L146-L189 HydrophobicContact CD1-CD2 4.36Å; L146-V190 HydrophobicContact CD1-CG2 3.82Å; L146-V190 HydrophobicContact CG-CG2 4.33Å; L146-F195 WeakPolarHBondContact CD2-O 3.49Å
147P98.3Very high96.6Very high8 Ų837.1 Ų37.15%0.05221%0.213CC..  trans-62.1122.9166.5-2131.7000110.7L125 M128 V159 P161L125-P147 HydrophobicContact CB-CB 4.4Å; L125-P147 HydrophobicContact CB-CG 4.31Å; L125-P147 HydrophobicContact CD2-CB 3.93Å; L125-P147 HydrophobicContact CD2-CG 4.28Å; M128-P147 HydrophobicContact CB-CB 3.89Å; P147-V159 HydrophobicContact CB-CB 4.43Å; P147-V159 WeakPolarHBondContact CD-O 3.49Å; P147-V159 PolarHBondContact O-N 3.46Å; P147-P161 HydrophobicContact CG-CG 4.26Å
148A98Very high96.7Very high0 Ų036.8 Ų36.80%021%0.21CC..EExtended strand (participates in β ladder)trans-141.7160.5177.400000111.8G132 M133 F140 L146 I156 L157 L158G132-A148 VanDerWaalsContact CA-O 3.23Å; G132-A148 WeakPolarHBondContact CA-O 3.27Å; M133-A148 HydrophobicContact CG-CB 4.19Å; M133-A148 HydrophobicContact SD-CB 3.64Å; F140-A148 HydrophobicContact CD1-CB 4.35Å; F140-A148 HydrophobicContact CE1-CB 3.49Å; F140-A148 VanDerWaalsContact CE1-CB 3.49Å; F140-A148 HydrophobicContact CZ-CB 3.77Å; L146-A148 PolarHBondContact O-N 2.86Å; A148-I156 HydrophobicContact CB-CG2 4.24Å; A148-L157 CarbonylContact C-O 3.58Å; A148-L157 WeakPolarHBondContact CA-O 3.34Å; A148-L158 HydrophobicContact CB-CD1 3.85Å
149K97.9Very high96.9Very high50 Ų5034.2 Ų34.222%0.21718%0.184CC..EExtended strand (participates in β ladder)trans-136.7123.6167.6-17476.9-156.970.40109.9M1 M128 G132 I156 L157M1-K149 HydrophobicContact SD-CD 3.94Å; M128-K149 HydrophobicContact CE-CB 4.27Å; G132-K149 WeakPolarHBondContact O-CA 3.43Å; G132-K149 VanDerWaalsContact O-CD 3.27Å; G132-K149 WeakPolarHBondContact O-CD 3.5Å; G132-K149 WeakPolarHBondContact O-CE 3.26Å; G132-K149 PolarHBondContact O-NZ 3.1Å; K149-I156 WeakPolarHBondContact O-CA 2.96Å; K149-L157 PolarHBondContact N-O 3.3Å; K149-L157 PolarHBondContact O-N 2.98Å
150S96.8Very high97Very high3 Ų329.1 Ų29.12%0.02116%0.161CC..EExtended strand (participates in β ladder)trans-88148.9174.3-172.70000111.9G132 M133 N178G132-S150 PolarHBondContact O-N 3.29Å; M133-S150 PolarHBondContact SD-N 2.86Å; M133-S150 VanDerWaalsContact SD-N 3.36Å; S150-N178 WeakPolarHBondContact CB-OD1 3.45Å; S150-N178 PolarHBondContact OG-OD1 3.38Å
151A94.8Very high97Very high36 Ų3630.7 Ų30.730%0.29817%0.171SC..  trans-127.4150.4173.200000110.9S153 G154 A155A151-S153 PolarHBondContact O-N 2.78Å; A151-G154 PolarHBondContact O-N 2.99Å; A151-A155 HydrophobicContact CB-CB 4.29Å; A151-A155 PolarHBondContact N-O 2.88Å
152V94.5Very high97Very high98 Ų9837.1 Ų37.159%0.59420%0.204SC*.THydrogen-bonded Turntrans-66-14.6177.9-63.80000113.4G154 L173V152-G154 PolarHBondContact O-N 2.92Å; V152-L173 HydrophobicContact CB-CD1 4.47Å; V152-L173 WeakPolarHBondContact O-CD1 3.27Å
153S94.4Very high97Very high72 Ų7232.5 Ų32.550%0.50319%0.188SC..THydrogen-bonded Turntrans-68.5-7.5168.657.50000113.4A151 A155A151-S153 PolarHBondContact O-N 2.78Å; S153-A155 VanDerWaalsContact C-N 3.34Å
154G95.3Very high97.1Very high0 Ų029.9 Ų29.90%018%0.177CC..SBendtrans83.611.2-172.800000113.5A151 V152 S170 S179A151-G154 PolarHBondContact O-N 2.99Å; V152-G154 PolarHBondContact O-N 2.92Å; G154-S170 WeakPolarHBondContact CA-O 3.41Å; G154-S170 PolarHBondContact O-N 3.33Å; G154-S179 VanDerWaalsContact O-CB 3.27Å; G154-S179 WeakPolarHBondContact O-CB 3.14Å; G154-S179 PolarHBondContact O-OG 2.88Å
155A97.1Very high97.1Very high15 Ų1530.5 Ų30.512%0.12418%0.183CC..EExtended strand (participates in β ladder)trans-82.8142.9172.100000111.3A151 S153 M167 C168 L169A151-A155 HydrophobicContact CB-CB 4.29Å; A151-A155 PolarHBondContact N-O 2.88Å; S153-A155 VanDerWaalsContact C-N 3.34Å; A155-M167 HydrophobicContact CB-SD 3.99Å; A155-C168 CarbonylContact C-O 3.41Å; A155-C168 VanDerWaalsContact CA-O 3.26Å; A155-C168 WeakPolarHBondContact CA-O 3.34Å; A155-L169 HydrophobicContact CB-CD1 4.03Å
156I98Very high97.2Very high0 Ų032.5 Ų32.50%019%0.193CC..EExtended strand (participates in β ladder)trans-129.1113.1169.8-60178.6000107.9M133 A148 K149 M167 C168 T183M133-I156 HydrophobicContact CE-CD1 3.8Å; M133-I156 HydrophobicContact CE-CG1 4.15Å; M133-I156 HydrophobicContact CE-CG2 4.02Å; M133-I156 HydrophobicContact SD-CG2 4.31Å; A148-I156 HydrophobicContact CB-CG2 4.24Å; K149-I156 WeakPolarHBondContact O-CA 2.96Å; I156-M167 VanDerWaalsContact C-SD 3.55Å; I156-M167 VanDerWaalsContact O-SD 3.36Å; I156-C168 HydrophobicContact CB-CB 4.47Å; I156-C168 PolarHBondContact N-O 3.02Å; I156-C168 PolarHBondContact O-N 3.36Å; I156-T183 HydrophobicContact CD1-CG2 3.95Å
157L98.3Very high97.2Very high38 Ų3834 Ų3420%0.19920%0.2CC..EExtended strand (participates in β ladder)trans-79.6119.1168.9-170.779.9000107.9G95 A99 L102 M128 A148 K149 M167G95-L157 WeakPolarHBondContact O-CD1 3.46Å; A99-L157 HydrophobicContact CB-CD1 3.69Å; A99-L157 HydrophobicContact CB-CG 4.14Å; L102-L157 HydrophobicContact CD1-CD2 4.41Å; M128-L157 HydrophobicContact CE-CD2 4.12Å; A148-L157 CarbonylContact C-O 3.58Å; A148-L157 WeakPolarHBondContact CA-O 3.34Å; K149-L157 PolarHBondContact N-O 3.3Å; K149-L157 PolarHBondContact O-N 2.98Å; L157-M167 HydrophobicContact CB-CE 4.13Å; L157-M167 HydrophobicContact CB-SD 4.46Å; L157-M167 HydrophobicContact CD1-CE 3.44Å; L157-M167 VanDerWaalsContact CD1-CE 3.44Å; L157-M167 HydrophobicContact CD1-SD 4.49Å; L157-M167 HydrophobicContact CG-CE 4.42Å
158L98.4Very high97.1Very high0 Ų034.5 Ų34.50%020%0.204CC..EExtended strand (participates in β ladder)trans-122.6132.8-176.7-177.871.1000109.9F140 L146 A148 M166 L189F140-L158 HydrophobicContact CE1-CD1 4.5Å; F140-L158 HydrophobicContact CZ-CD1 4.18Å; L146-L158 HydrophobicContact CB-CD1 3.69Å; L146-L158 HydrophobicContact CD1-CD1 3.99Å; L146-L158 HydrophobicContact CD1-CD2 4.24Å; L146-L158 HydrophobicContact CD1-CG 4.36Å; A148-L158 HydrophobicContact CB-CD1 3.85Å; L158-M166 HydrophobicContact CB-CB 4.32Å; L158-M166 HydrophobicContact CD2-SD 4.36Å; L158-M166 PolarHBondContact N-O 3.24Å; L158-M166 PolarHBondContact O-N 3.18Å; L158-M166 VanDerWaalsContact O-O 3.11Å; L158-L189 HydrophobicContact CD2-CD2 4.07Å
159V98.6Very high97.1Very high0 Ų039.2 Ų39.20%023%0.229CC..EExtended strand (participates in β ladder)trans-121.1130.1-179.9-174.50000109.7A99 L102 A103 L125 M128 P147A99-V159 HydrophobicContact CB-CG2 4.17Å; L102-V159 HydrophobicContact CB-CG1 4.42Å; L102-V159 HydrophobicContact CB-CG2 4.24Å; L102-V159 HydrophobicContact CD1-CG2 4.28Å; A103-V159 HydrophobicContact CB-CG1 3.77Å; L125-V159 HydrophobicContact CD2-CB 3.82Å; L125-V159 HydrophobicContact CD2-CG1 3.68Å; L125-V159 HydrophobicContact CD2-CG2 3.94Å; M128-V159 HydrophobicContact CE-CG2 3.98Å; P147-V159 HydrophobicContact CB-CB 4.43Å; P147-V159 WeakPolarHBondContact CD-O 3.49Å; P147-V159 PolarHBondContact O-N 3.46Å
160V98.1Very high97.1Very high6 Ų637.3 Ų37.34%0.03622%0.222CC..EExtended strand (participates in β ladder)trans-10997.3166.5-171.30000107.1L146 N162 V163 M164 F195L146-V160 HydrophobicContact CD1-CG2 4.06Å; L146-V160 HydrophobicContact CD2-CB 4.42Å; L146-V160 HydrophobicContact CD2-CG1 4.27Å; L146-V160 HydrophobicContact CD2-CG2 4Å; V160-N162 PolarHBondContact O-N 3.19Å; V160-V163 HydrophobicContact CB-CB 4.12Å; V160-V163 HydrophobicContact CG1-CB 3.7Å; V160-V163 HydrophobicContact CG1-CG1 4.33Å; V160-V163 HydrophobicContact CG1-CG2 3.9Å; V160-V163 PolarHBondContact O-N 2.86Å; V160-M164 CarbonylContact C-O 3.58Å; V160-M164 WeakPolarHBondContact CA-O 3.43Å; V160-M164 HydrophobicContact CB-CG 4.1Å; V160-M164 HydrophobicContact CG2-CE 4.04Å; V160-M164 HydrophobicContact CG2-CG 4.14Å; V160-M164 PolarHBondContact N-O 3.18Å; V160-M164 PolarHBondContact O-N 3.23Å; V160-M164 VanDerWaalsContact O-O 3.06Å; V160-F195 HydrophobicContact CG1-CB 4.23Å; V160-F195 HydrophobicContact CG1-CD1 4.01Å; V160-F195 HydrophobicContact CG1-CG 4.17Å
161P97.7Very high97.1Very high36 Ų3641.4 Ų41.423%0.23425%0.248CC..THydrogen-bonded Turntrans-54.8136.1-172-26.234.8000112.6L125 P147 V163L125-P161 HydrophobicContact CD1-CG 4.35Å; P147-P161 HydrophobicContact CG-CG 4.26Å; P161-V163 PolarHBondContact O-N 2.96Å
162N96.6Very high97.2Very high148 Ų14843.8 Ų43.879%0.79126%0.261SS*.THydrogen-bonded Turntrans60.314.4-176.7-44.8-66.6000115.4A103 V160A103-N162 PolarHBondContact O-N 3.09Å; V160-N162 PolarHBondContact O-N 3.19Å
163V96.3Very high97.3Very high56 Ų5642.4 Ų42.434%0.33925%0.249SC..THydrogen-bonded Turntrans-127.7-65.6178.6-176.20000111V160 P161 F195V160-V163 HydrophobicContact CB-CB 4.12Å; V160-V163 HydrophobicContact CG1-CB 3.7Å; V160-V163 HydrophobicContact CG1-CG1 4.33Å; V160-V163 HydrophobicContact CG1-CG2 3.9Å; V160-V163 PolarHBondContact O-N 2.86Å; P161-V163 PolarHBondContact O-N 2.96Å; V163-F195 HydrophobicContact CG1-CE1 4.05Å; V163-F195 HydrophobicContact CG1-CZ 4.42Å
164M97.4Very high97.3Very high59 Ų5941.2 Ų41.229%0.29124%0.237SC..EExtended strand (participates in β ladder)trans-162.6164.1-174.764-179.7177.400112.4A103 V160 M166 F195A103-M164 WeakPolarHBondContact CB-O 3.3Å; V160-M164 CarbonylContact C-O 3.58Å; V160-M164 WeakPolarHBondContact CA-O 3.43Å; V160-M164 HydrophobicContact CB-CG 4.1Å; V160-M164 HydrophobicContact CG2-CE 4.04Å; V160-M164 HydrophobicContact CG2-CG 4.14Å; V160-M164 PolarHBondContact N-O 3.18Å; V160-M164 PolarHBondContact O-N 3.23Å; V160-M164 VanDerWaalsContact O-O 3.06Å; M164-M166 HydrophobicContact CE-CG 4.33Å; M164-M166 HydrophobicContact CE-SD 3.53Å; M164-M166 VanDerWaalsContact CE-SD 3.53Å; M164-M166 HydrophobicContact CG-CG 4.43Å; M164-M166 HydrophobicContact SD-CG 4.24Å; M164-M166 HydrophobicContact SD-SD 4.08Å; M164-F195 HydrophobicContact CE-CD2 4.24Å; M164-F195 HydrophobicContact CE-CE2 3.73Å; M164-F195 HydrophobicContact CE-CZ 4.22Å
165G97.9Very high97.3Very high13 Ų1351.5 Ų51.513%0.13428%0.282CS..EExtended strand (participates in β ladder)trans-117149.5165.500000111.1
166M98.1Very high97.1Very high43 Ų4354.3 Ų54.321%0.21230%0.295CS..EExtended strand (participates in β ladder)trans-139.1151.3-178.6-56.5-177.274.600110.6L158 M164 F185 L189L158-M166 HydrophobicContact CB-CB 4.32Å; L158-M166 HydrophobicContact CD2-SD 4.36Å; L158-M166 PolarHBondContact N-O 3.24Å; L158-M166 PolarHBondContact O-N 3.18Å; L158-M166 VanDerWaalsContact O-O 3.11Å; M164-M166 HydrophobicContact CE-CG 4.33Å; M164-M166 HydrophobicContact CE-SD 3.53Å; M164-M166 VanDerWaalsContact CE-SD 3.53Å; M164-M166 HydrophobicContact CG-CG 4.43Å; M164-M166 HydrophobicContact SD-CG 4.24Å; M164-M166 HydrophobicContact SD-SD 4.08Å; M166-F185 HydrophobicContact CE-CE1 3.7Å; M166-F185 HydrophobicContact CE-CZ 3.73Å; M166-F185 HydrophobicContact SD-CE1 4.4Å; M166-L189 HydrophobicContact SD-CD2 4.24Å
167M98.1Very high96.8Very high33 Ų3355.2 Ų55.216%0.16330%0.304CS..EExtended strand (participates in β ladder)trans-125.6126.7168.9-179.164.28200108.7V90 C92 A155 I156 L157V90-M167 HydrophobicContact CG2-CE 4.45Å; C92-M167 HydrophobicContact CB-CG 4.44Å; C92-M167 WeakPolarHBondContact O-CB 3.18Å; A155-M167 HydrophobicContact CB-SD 3.99Å; I156-M167 VanDerWaalsContact C-SD 3.55Å; I156-M167 VanDerWaalsContact O-SD 3.36Å; L157-M167 HydrophobicContact CB-CE 4.13Å; L157-M167 HydrophobicContact CB-SD 4.46Å; L157-M167 HydrophobicContact CD1-CE 3.44Å; L157-M167 VanDerWaalsContact CD1-CE 3.44Å; L157-M167 HydrophobicContact CD1-SD 4.49Å; L157-M167 HydrophobicContact CG-CE 4.42Å
168C97.1Very high96.7Very high19 Ų1953.4 Ų53.413%0.12829%0.294CS..EExtended strand (participates in β ladder)trans-109.7134.7172.2-58.30000109.1A155 I156A155-C168 CarbonylContact C-O 3.41Å; A155-C168 VanDerWaalsContact CA-O 3.26Å; A155-C168 WeakPolarHBondContact CA-O 3.34Å; I156-C168 HydrophobicContact CB-CB 4.47Å; I156-C168 PolarHBondContact N-O 3.02Å; I156-C168 PolarHBondContact O-N 3.36Å
169L97.5Very high96.7Very high99 Ų9953.4 Ų53.452%0.51829%0.294SS..EExtended strand (participates in β ladder)trans-125.6122.3176.1-179.363.9000110.4C92 A155C92-L169 WeakPolarHBondContact SG-CB 3.42Å; A155-L169 HydrophobicContact CB-CD1 4.03Å
170S97.5Very high96.5Very high10 Ų1059.2 Ų59.27%0.0732%0.321CS..  trans-153.7104.8169.8158.10000108.3G154 P172 S179G154-S170 WeakPolarHBondContact CA-O 3.41Å; G154-S170 PolarHBondContact O-N 3.33Å; S170-P172 VanDerWaalsContact C-CD 3.43Å; S170-S179 WeakPolarHBondContact CB-OG 3.41Å; S170-S179 WeakPolarHBondContact O-CB 3.3Å; S170-S179 PolarHBondContact O-OG 3.31Å; S170-S179 PolarHBondContact OG-OG 3.07Å
171P96.4Very high96.4Very high88 Ų8867.8 Ų67.857%0.57135%0.353SS*.  trans-54.5-35.1-174.8-28.135.1000116.5L173P171-L173 WeakPolarHBondContact O-CG 3.29Å; P171-L173 PolarHBondContact O-N 3.48Å; P171-L173 VanDerWaalsContact O-N 3.14Å
172P97.5Very high96.4Very high87 Ų8766.2 Ų66.257%0.56534%0.343SS*.  trans-61.4117.5176.5-26.536.3000112.7S170 H180S170-P172 VanDerWaalsContact C-CD 3.43Å; P172-H180 PolarHBondContact O-N 3.26Å; P172-H180 VanDerWaalsContact O-N 3.12Å
173L96.9Very high96.3Very high68 Ų6859.7 Ų59.736%0.35631%0.309SS..BIsolated β-bridgetrans-95.9152.8-179.3-53.4-177.2000112.1V152 P171 N178V152-L173 HydrophobicContact CB-CD1 4.47Å; V152-L173 WeakPolarHBondContact O-CD1 3.27Å; P171-L173 WeakPolarHBondContact O-CG 3.29Å; P171-L173 PolarHBondContact O-N 3.48Å; P171-L173 VanDerWaalsContact O-N 3.14Å; L173-N178 CarbonylContact C-O 3.45Å; L173-N178 VanDerWaalsContact CA-O 3.3Å; L173-N178 WeakPolarHBondContact CA-O 3.42Å
174D94.2Very high96.4Very high47 Ų4759 Ų5925%0.25131%0.306SS..  trans-79.5179.5166.269.817.9000111.9L176 G177 N178D174-L176 PolarHBondContact O-N 2.86Å; D174-L176 VanDerWaalsContact O-N 3.15Å; D174-L176 WeakPolarHBondContact OD1-CA 3.34Å; D174-L176 WeakPolarHBondContact OD1-CB 3.45Å; D174-L176 PolarHBondContact OD1-N 2.88Å; D174-G177 PolarHBondContact O-N 3.33Å; D174-G177 VanDerWaalsContact O-N 3.14Å; D174-G177 PolarHBondContact OD1-N 2.86Å; D174-N178 VanDerWaalsContact CG-O 3.31Å; D174-N178 PolarHBondContact N-O 3.14Å; D174-N178 PolarHBondContact OD1-N 2.96Å
175K94.8Very high96.4Very high216 Ų21660.4 Ų60.494%0.93931%0.311SS*.THydrogen-bonded Turntrans-64.1-17.4179.5-62.6-177.5-178.7179.60113.8
176L93.4Very high96.3Very high75 Ų7559.8 Ų59.839%0.39331%0.305SS..THydrogen-bonded Turntrans-98.51.1-179-57.9178.6000112.1Y134 F136 D174Y134-L176 WeakPolarHBondContact CD2-O 3.45Å; F136-L176 HydrophobicContact CB-CD1 3.93Å; F136-L176 HydrophobicContact CD2-CD1 4.03Å; F136-L176 HydrophobicContact CG-CD1 4.35Å; D174-L176 PolarHBondContact O-N 2.86Å; D174-L176 VanDerWaalsContact O-N 3.15Å; D174-L176 WeakPolarHBondContact OD1-CA 3.34Å; D174-L176 WeakPolarHBondContact OD1-CB 3.45Å; D174-L176 PolarHBondContact OD1-N 2.88Å
177G92.3Very high96.3Very high18 Ų1861.6 Ų61.619%0.18631%0.313CS..SBendtrans85.312.417900000114.6Y134 D174Y134-G177 VanDerWaalsContact CE2-O 3.3Å; Y134-G177 WeakPolarHBondContact CE2-O 3.24Å; D174-G177 PolarHBondContact O-N 3.33Å; D174-G177 VanDerWaalsContact O-N 3.14Å; D174-G177 PolarHBondContact OD1-N 2.86Å
178N96.2Very high96.2Very high0 Ų066.9 Ų66.90%033%0.334CS..SBendtrans-98.2150.4176.8-61.4-57.2000111.9M133 Y134 F136 S150 L173 D174 H180 T183M133-N178 PolarHBondContact O-ND2 3.2Å; M133-N178 VanDerWaalsContact O-ND2 3.16Å; Y134-N178 VanDerWaalsContact CD2-OD1 3.28Å; Y134-N178 WeakPolarHBondContact CD2-OD1 3.45Å; F136-N178 VanDerWaalsContact CB-ND2 3.34Å; F136-N178 WeakPolarHBondContact CB-ND2 3.27Å; S150-N178 WeakPolarHBondContact CB-OD1 3.45Å; S150-N178 PolarHBondContact OG-OD1 3.38Å; L173-N178 CarbonylContact C-O 3.45Å; L173-N178 VanDerWaalsContact CA-O 3.3Å; L173-N178 WeakPolarHBondContact CA-O 3.42Å; D174-N178 VanDerWaalsContact CG-O 3.31Å; D174-N178 PolarHBondContact N-O 3.14Å; D174-N178 PolarHBondContact OD1-N 2.96Å; N178-H180 PolarHBondContact O-N 2.83Å; N178-T183 HydrophobicContact CB-CG2 3.86Å
179S97.3Very high96.2Very high0 Ų066.8 Ų66.80%033%0.333CS..BIsolated β-bridgetrans-63.6122.8175.9-177.50000112.1G154 S170 G182 T183G154-S179 VanDerWaalsContact O-CB 3.27Å; G154-S179 WeakPolarHBondContact O-CB 3.14Å; G154-S179 PolarHBondContact O-OG 2.88Å; S170-S179 WeakPolarHBondContact CB-OG 3.41Å; S170-S179 WeakPolarHBondContact O-CB 3.3Å; S170-S179 PolarHBondContact O-OG 3.31Å; S170-S179 PolarHBondContact OG-OG 3.07Å; S179-G182 PolarHBondContact O-N 3.15Å; S179-G182 PolarHBondContact OG-N 2.74Å; S179-T183 WeakPolarHBondContact O-CG2 3.31Å; S179-T183 PolarHBondContact O-N 3.27Å; S179-T183 PolarHBondContact O-OG1 2.89Å; S179-T183 VanDerWaalsContact O-OG1 3.1Å
180H94.7Very high96.1Very high122 Ų12262.3 Ų62.357%0.56531%0.309SS*.Hα-helixtrans-63.2-47.5-175.5-172.870.2000112.9P172 N178 T183 S184P172-H180 PolarHBondContact O-N 3.26Å; P172-H180 VanDerWaalsContact O-N 3.12Å; N178-H180 PolarHBondContact O-N 2.83Å; H180-T183 PolarHBondContact O-OG1 3.23Å; H180-T183 VanDerWaalsContact O-OG1 3.12Å; H180-S184 WeakPolarHBondContact O-CB 3.48Å; H180-S184 PolarHBondContact O-N 3.02Å
181R96.7Very high95.9Very high187 Ų18766.2 Ų66.271%0.70634%0.337SS*.Hα-helixtrans-71.6-35.3178.1-64.5178.766-173.3-0.4111.5S184 F185R181-S184 PolarHBondContact O-N 3.2Å; R181-F185 WeakPolarHBondContact O-CB 3.48Å; R181-F185 PolarHBondContact O-N 3.26Å
182G96.8Very high95.8Very high2 Ų266.2 Ų66.22%0.02133%0.331CS..Hα-helixtrans-64.7-44.8179.700000112.5S179 F185 C186S179-G182 PolarHBondContact O-N 3.15Å; S179-G182 PolarHBondContact OG-N 2.74Å; G182-F185 PolarHBondContact O-N 3.2Å; G182-C186 PolarHBondContact O-N 2.8Å; G182-C186 VanDerWaalsContact O-N 3.07Å; G182-C186 PolarHBondContact O-SG 3.45Å
183T95.9Very high95.6Very high12 Ų1264.3 Ų64.37%0.07431%0.314CS..Hα-helixtrans-67.2-41.6176.454.70000112M133 I156 N178 S179 H180 F185 C186 Q187M133-T183 HydrophobicContact CE-CG2 4.22Å; I156-T183 HydrophobicContact CD1-CG2 3.95Å; N178-T183 HydrophobicContact CB-CG2 3.86Å; S179-T183 WeakPolarHBondContact O-CG2 3.31Å; S179-T183 PolarHBondContact O-N 3.27Å; S179-T183 PolarHBondContact O-OG1 2.89Å; S179-T183 VanDerWaalsContact O-OG1 3.1Å; H180-T183 PolarHBondContact O-OG1 3.23Å; H180-T183 VanDerWaalsContact O-OG1 3.12Å; T183-F185 VanDerWaalsContact C-N 3.32Å; T183-F185 PolarHBondContact O-N 3.34Å; T183-C186 PolarHBondContact O-N 2.71Å; T183-Q187 WeakPolarHBondContact O-CG 3.39Å; T183-Q187 PolarHBondContact O-N 2.88Å; T183-Q187 VanDerWaalsContact O-N 3.08Å
184S97.1Very high95.5Very high42 Ų4261.3 Ų61.329%0.29430%0.299SS..Hα-helixtrans-60.5-40.8175.1-1730000112.2H180 R181 Q187 K188H180-S184 WeakPolarHBondContact O-CB 3.48Å; H180-S184 PolarHBondContact O-N 3.02Å; R181-S184 PolarHBondContact O-N 3.2Å; S184-Q187 PolarHBondContact O-N 3.19Å; S184-K188 WeakPolarHBondContact O-CG 3.42Å; S184-K188 PolarHBondContact O-N 2.77Å; S184-K188 VanDerWaalsContact O-N 3.09Å
185F97.8Very high95.6Very high88 Ų8859.8 Ų59.839%0.38629%0.29SS..Hα-helixtrans-60.6-48.2174175.8-94.9000111.6M166 R181 G182 T183 Q187 K188 L189M166-F185 HydrophobicContact CE-CE1 3.7Å; M166-F185 HydrophobicContact CE-CZ 3.73Å; M166-F185 HydrophobicContact SD-CE1 4.4Å; R181-F185 WeakPolarHBondContact O-CB 3.48Å; R181-F185 PolarHBondContact O-N 3.26Å; G182-F185 PolarHBondContact O-N 3.2Å; T183-F185 VanDerWaalsContact C-N 3.32Å; T183-F185 PolarHBondContact O-N 3.34Å; F185-Q187 VanDerWaalsContact C-N 3.3Å; F185-Q187 PolarHBondContact O-N 3.08Å; F185-K188 PolarHBondContact O-N 2.72Å; F185-L189 HydrophobicContact CZ-CD1 4.44Å; F185-L189 WeakPolarHBondContact O-CB 3.2Å; F185-L189 PolarHBondContact O-N 3.43Å
186C97.1Very high95.7Very high0 Ų051 Ų510%025%0.252CS..Hα-helixtrans-58.6-40.2179.2-650000112.6F140 V144 G182 T183 L189 V190F140-C186 HydrophobicContact CE2-CB 3.85Å; F140-C186 HydrophobicContact CZ-CB 3.99Å; V144-C186 HydrophobicContact CG1-CB 4.06Å; V144-C186 HydrophobicContact CG2-CB 4.4Å; G182-C186 PolarHBondContact O-N 2.8Å; G182-C186 VanDerWaalsContact O-N 3.07Å; G182-C186 PolarHBondContact O-SG 3.45Å; T183-C186 PolarHBondContact O-N 2.71Å; C186-L189 WeakPolarHBondContact O-CB 3.41Å; C186-L189 PolarHBondContact O-N 3.36Å; C186-V190 PolarHBondContact O-N 2.83Å
187Q96.4Very high95.7Very high81 Ų8151.5 Ų51.538%0.37926%0.255SS..Hα-helixtrans-67.5-41.7177-71.6174.9-15.500112.8V144 T183 S184 F185 L189 S191V144-Q187 HydrophobicContact CG2-CG 3.85Å; T183-Q187 WeakPolarHBondContact O-CG 3.39Å; T183-Q187 PolarHBondContact O-N 2.88Å; T183-Q187 VanDerWaalsContact O-N 3.08Å; S184-Q187 PolarHBondContact O-N 3.19Å; F185-Q187 VanDerWaalsContact C-N 3.3Å; F185-Q187 PolarHBondContact O-N 3.08Å; Q187-L189 VanDerWaalsContact C-N 3.34Å; Q187-S191 WeakPolarHBondContact O-CB 3.41Å; Q187-S191 PolarHBondContact O-N 2.89Å; Q187-S191 PolarHBondContact O-OG 2.87Å
188K96.9Very high95.9Very high143 Ų14358.8 Ų58.862%0.62228%0.278SS*.Hα-helixtrans-66.9-37176.3-72.2-179.9-177.7-177.50111.7S184 F185 V190 S191 L192S184-K188 WeakPolarHBondContact O-CG 3.42Å; S184-K188 PolarHBondContact O-N 2.77Å; S184-K188 VanDerWaalsContact O-N 3.09Å; F185-K188 PolarHBondContact O-N 2.72Å; K188-V190 PolarHBondContact O-N 3.34Å; K188-S191 PolarHBondContact O-N 3.31Å; K188-L192 PolarHBondContact O-N 3.49Å; K188-L192 VanDerWaalsContact O-N 3.09Å
189L96.6Very high95.7Very high17 Ų1761 Ų619%0.08929%0.29CS..Hα-helixtrans-56.7-51.5176.9-17674.2000111.1L146 L158 M166 F185 C186 Q187 S191 L192 F193 F195L146-L189 HydrophobicContact CD1-CD2 4.36Å; L158-L189 HydrophobicContact CD2-CD2 4.07Å; M166-L189 HydrophobicContact SD-CD2 4.24Å; F185-L189 HydrophobicContact CZ-CD1 4.44Å; F185-L189 WeakPolarHBondContact O-CB 3.2Å; F185-L189 PolarHBondContact O-N 3.43Å; C186-L189 WeakPolarHBondContact O-CB 3.41Å; C186-L189 PolarHBondContact O-N 3.36Å; Q187-L189 VanDerWaalsContact C-N 3.34Å; L189-S191 VanDerWaalsContact C-N 3.35Å; L189-L192 PolarHBondContact O-N 3.33Å; L189-F193 HydrophobicContact CD1-CD2 3.77Å; L189-F193 HydrophobicContact CD1-CE2 4.1Å; L189-F193 HydrophobicContact CG-CD2 4.44Å; L189-F193 WeakPolarHBondContact O-CB 3.47Å; L189-F193 WeakPolarHBondContact O-CD2 3.44Å; L189-F193 PolarHBondContact O-N 3.44Å; L189-F195 HydrophobicContact CD1-CD2 4.45Å; L189-F195 HydrophobicContact CD2-CD2 4.45Å; L189-F195 HydrophobicContact CG-CD2 4.24Å
190V95.2Very high95.4Very high5 Ų564.9 Ų64.93%0.0331%0.311CS..Hα-helixtrans-78.1-20.9-177.4177.70000112.9V144 L146 C186 K188 L192 F193 H196 K207V144-V190 HydrophobicContact CG1-CG2 3.79Å; L146-V190 HydrophobicContact CD1-CG2 3.82Å; L146-V190 HydrophobicContact CG-CG2 4.33Å; C186-V190 PolarHBondContact O-N 2.83Å; K188-V190 PolarHBondContact O-N 3.34Å; V190-L192 VanDerWaalsContact C-N 3.33Å; V190-F193 CarbonylContact C-O 3.58Å; V190-H196 HydrophobicContact CG1-CB 3.61Å; V190-K207 VanDerWaalsContact O-CE 3.3Å; V190-K207 WeakPolarHBondContact O-CE 3.26Å; V190-K207 PolarHBondContact O-NZ 3.29Å
191S94.1Very high95Very high92 Ų9263.1 Ų63.164%0.64331%0.305SS*.Hα-helixtrans-67.3-35.8168.7-62.80000111.9Q187 K188 L189Q187-S191 WeakPolarHBondContact O-CB 3.41Å; Q187-S191 PolarHBondContact O-N 2.89Å; Q187-S191 PolarHBondContact O-OG 2.87Å; K188-S191 PolarHBondContact O-N 3.31Å; L189-S191 VanDerWaalsContact C-N 3.35Å
192L94.3Very high94.1Very high88 Ų8863.8 Ų63.846%0.46131%0.308SS..Hα-helixtrans-88.7-38.9-178.6-176.261.8000113.1K188 L189 V190 K207 L208K188-L192 PolarHBondContact O-N 3.49Å; K188-L192 VanDerWaalsContact O-N 3.09Å; L189-L192 PolarHBondContact O-N 3.33Å; V190-L192 VanDerWaalsContact C-N 3.33Å; L192-K207 CarbonylContact O-C 3.59Å; L192-K207 WeakPolarHBondContact O-CA 3.45Å; L192-K207 WeakPolarHBondContact O-CB 3.21Å; L192-L208 HydrophobicContact CD1-CD1 3.97Å; L192-L208 HydrophobicContact CD1-CG 4.46Å; L192-L208 HydrophobicContact CG-CD1 4.17Å; L192-L208 PolarHBondContact O-N 2.7Å
193F94.2Very high93.1Very high48 Ų4870 Ų7021%0.21134%0.336CS..BIsolated β-bridgetrans-114.4149.2-173.9-62.3-77.9000112.6L189 V190 F195 K207 L208 P210L189-F193 HydrophobicContact CD1-CD2 3.77Å; L189-F193 HydrophobicContact CD1-CE2 4.1Å; L189-F193 HydrophobicContact CG-CD2 4.44Å; L189-F193 WeakPolarHBondContact O-CB 3.47Å; L189-F193 WeakPolarHBondContact O-CD2 3.44Å; L189-F193 PolarHBondContact O-N 3.44Å; V190-F193 CarbonylContact C-O 3.58Å; F193-F195 HydrophobicContact CB-CD2 3.38Å; F193-F195 HydrophobicContact CB-CE2 3.5Å; F193-F195 VanDerWaalsContact CB-CE2 3.5Å; F193-F195 HydrophobicContact CB-CG 3.96Å; F193-F195 HydrophobicContact CB-CZ 4.17Å; F193-F195 HydrophobicContact CD1-CE2 4.19Å; F193-F195 HydrophobicContact CD1-CZ 4.47Å; F193-F195 HydrophobicContact CD2-CD2 4.41Å; F193-F195 HydrophobicContact CD2-CE2 4.09Å; F193-F195 HydrophobicContact CG-CD2 4.04Å; F193-F195 AromaticContact CG-CE2 3.68Å; F193-F195 HydrophobicContact CG-CE2 3.68Å; F193-F195 HydrophobicContact CG-CZ 4.35Å; F193-F195 PolarHBondContact O-N 3.14Å; F193-K207 WeakPolarHBondContact O-CD 3.5Å; F193-L208 VanDerWaalsContact CA-O 3.29Å; F193-L208 WeakPolarHBondContact CA-O 3.29Å; F193-L208 HydrophobicContact CD1-CB 3.62Å; F193-L208 HydrophobicContact CE1-CB 3.76Å; F193-L208 HydrophobicContact CE1-CD1 4.11Å; F193-P210 HydrophobicContact CD1-CG 3.59Å; F193-P210 HydrophobicContact CE1-CG 3.58Å
194N94.1Very high91.8Very high4 Ų471.3 Ų71.32%0.02135%0.345CS..SBendtrans-78.947.5177.870.9-20.6000113.3D199 C204 K207 L208 D209 R211N194-D199 WeakPolarHBondContact CA-OD2 3.47Å; N194-D199 HydrophobicContact CB-CB 4.35Å; N194-C204 HydrophobicContact CB-CB 4.45Å; N194-K207 HydrophobicContact CB-CB 4.16Å; N194-K207 HydrophobicContact CB-CD 4.4Å; N194-L208 PolarHBondContact N-O 3.08Å; N194-L208 VanDerWaalsContact N-O 3.08Å; N194-L208 PolarHBondContact OD1-O 3.48Å; N194-D209 PolarHBondContact ND2-OD2 2.86Å; N194-D209 WeakPolarHBondContact OD1-CA 3.39Å; N194-D209 VanDerWaalsContact OD1-CB 3.31Å; N194-D209 WeakPolarHBondContact OD1-CB 3.49Å; N194-D209 VanDerWaalsContact OD1-CG 3.24Å; N194-D209 PolarHBondContact OD1-OD2 3.48Å; N194-R211 PolarHBondContact ND2-NH2 3.43Å; N194-R211 PolarHBondContact OD1-NH2 3.45Å; N194-R211 VanDerWaalsContact OD1-NH2 3.1Å
195F96Very high90.1Very high15 Ų1573.9 Ų73.97%0.06637%0.369CS..  trans-94.4-6-178.7-65.1-37.1000114.2L146 V160 V163 M164 L189 F193 N197 P210L146-F195 WeakPolarHBondContact CD2-O 3.49Å; V160-F195 HydrophobicContact CG1-CB 4.23Å; V160-F195 HydrophobicContact CG1-CD1 4.01Å; V160-F195 HydrophobicContact CG1-CG 4.17Å; V163-F195 HydrophobicContact CG1-CE1 4.05Å; V163-F195 HydrophobicContact CG1-CZ 4.42Å; M164-F195 HydrophobicContact CE-CD2 4.24Å; M164-F195 HydrophobicContact CE-CE2 3.73Å; M164-F195 HydrophobicContact CE-CZ 4.22Å; L189-F195 HydrophobicContact CD1-CD2 4.45Å; L189-F195 HydrophobicContact CD2-CD2 4.45Å; L189-F195 HydrophobicContact CG-CD2 4.24Å; F193-F195 HydrophobicContact CB-CD2 3.38Å; F193-F195 HydrophobicContact CB-CE2 3.5Å; F193-F195 VanDerWaalsContact CB-CE2 3.5Å; F193-F195 HydrophobicContact CB-CG 3.96Å; F193-F195 HydrophobicContact CB-CZ 4.17Å; F193-F195 HydrophobicContact CD1-CE2 4.19Å; F193-F195 HydrophobicContact CD1-CZ 4.47Å; F193-F195 HydrophobicContact CD2-CD2 4.41Å; F193-F195 HydrophobicContact CD2-CE2 4.09Å; F193-F195 HydrophobicContact CG-CD2 4.04Å; F193-F195 AromaticContact CG-CE2 3.68Å; F193-F195 HydrophobicContact CG-CE2 3.68Å; F193-F195 HydrophobicContact CG-CZ 4.35Å; F193-F195 PolarHBondContact O-N 3.14Å; F195-N197 PolarHBondContact O-N 3.25Å; F195-P210 HydrophobicContact CZ-CG 3.88Å
196H96.5Very high89.2Confident31 Ų3181.1 Ų81.114%0.14439%0.394CS..SBendtrans-56134.9173.5-165.1-89.8000109.1F142 V144 G145 V190 Y198 D199F142-H196 PolarHBondContact O-NE2 3.07Å; V144-H196 PolarHBondContact O-CD2 3.04Å; G145-H196 WeakPolarHBondContact CA-NE2 3.3Å; V190-H196 HydrophobicContact CG1-CB 3.61Å; H196-Y198 AromaticContact CE1-CD2 3.8Å; H196-Y198 PolarHBondContact ND1-N 3.43Å; H196-Y198 VanDerWaalsContact ND1-N 3.18Å; H196-Y198 PolarHBondContact O-N 3.22Å; H196-D199 HydrophobicContact CB-CB 3.89Å; H196-D199 VanDerWaalsContact CB-CG 3.41Å; H196-D199 WeakPolarHBondContact CB-OD2 3.18Å; H196-D199 PolarHBondContact N-OD2 2.97Å; H196-D199 WeakPolarHBondContact O-CB 3.47Å; H196-D199 PolarHBondContact O-N 3.4Å
197N94.4Very high88.8Confident87 Ų8783.8 Ų83.847%0.46541%0.405SS..THydrogen-bonded Turntrans-60.8-20.2-176.2-171.455.2000113.5G145 F195G145-N197 WeakPolarHBondContact O-CB 3.33Å; G145-N197 PolarHBondContact O-N 3.49Å; F195-N197 PolarHBondContact O-N 3.25Å
198Y94.8Very high88.4Confident170 Ų17084.5 Ų84.567%0.66741%0.411SS*.THydrogen-bonded Turntrans-108.913.4174.9-56.3-69.8000114.2H196H196-Y198 AromaticContact CE1-CD2 3.8Å; H196-Y198 PolarHBondContact ND1-N 3.43Å; H196-Y198 VanDerWaalsContact ND1-N 3.18Å; H196-Y198 PolarHBondContact O-N 3.22Å
199D93.6Very high88Confident47 Ų4779 Ų7925%0.25139%0.389SS..  trans-73.4156172.2-93.9-25.2000111.7N194 H196 K207N194-D199 WeakPolarHBondContact CA-OD2 3.47Å; N194-D199 HydrophobicContact CB-CB 4.35Å; H196-D199 HydrophobicContact CB-CB 3.89Å; H196-D199 VanDerWaalsContact CB-CG 3.41Å; H196-D199 WeakPolarHBondContact CB-OD2 3.18Å; H196-D199 PolarHBondContact N-OD2 2.97Å; H196-D199 WeakPolarHBondContact O-CB 3.47Å; H196-D199 PolarHBondContact O-N 3.4Å; D199-K207 IonicContact OD1-NZ 2.86Å; D199-K207 PolarHBondContact OD1-NZ 3.49Å; D199-K207 IonicContact OD2-NZ 3.53Å; D199-K207 PolarHBondContact OD2-NZ 3.32Å
200N89.6Confident87.7Confident81 Ų8182 Ų8243%0.43341%0.408SS..  trans-87.4129.3178.3-164.3-60.6000111.7R202 H203N200-R202 WeakPolarHBondContact OD1-CA 3.35Å; N200-R202 PolarHBondContact OD1-N 3.47Å; N200-H203 PolarHBondContact OD1-N 3.1Å
201L87Confident87.2Confident85 Ų8587.1 Ų87.145%0.44543%0.427SS..SBendtrans-80.5-20.1178.7-56.1-175.9000113.8R211 R212L201-R211 VanDerWaalsContact CD2-CZ 3.5Å; L201-R212 VanDerWaalsContact O-CZ 3.24Å; L201-R212 PolarHBondContact O-NH1 3.1Å; L201-R212 PolarHBondContact O-NH2 3.25Å
202R78.7Confident86.4Confident202 Ų20287.8 Ų87.876%0.76242%0.416SS*.SBendtrans-99.1-48.7-176.2-69.1-175.3176.6169.7-0.7112.2N200N200-R202 WeakPolarHBondContact OD1-CA 3.35Å; N200-R202 PolarHBondContact OD1-N 3.47Å
203H74.7Confident85.4Confident132 Ų13290 Ų9061%0.61142%0.424SS*.  trans-11380.5-173.6-55.3-66.9000109.3N200N200-H203 PolarHBondContact OD1-N 3.1Å
204C68.6Low84Confident40 Ų4089.9 Ų89.927%0.2744%0.436SS..  trans-127.196173.4-149.10000108.5N194 R206N194-C204 HydrophobicContact CB-CB 4.45Å; C204-R206 VanDerWaalsContact C-N 3.34Å; C204-R206 PolarHBondContact O-N 3.12Å
205A61.4Low82.5Confident95 Ų9592.4 Ų92.479%0.78546%0.457SS*.SBendtrans-75.1-20.5-167.400000114.2
206R79.4Confident81Confident241 Ų24196 Ų9691%0.90947%0.474SS*.SBendtrans-126.4-19-173.3-68.3-174178-179.6-0.8115.6C204C204-R206 VanDerWaalsContact C-N 3.34Å; C204-R206 PolarHBondContact O-N 3.12Å
207K88.8Confident79.7Confident56 Ų5697.1 Ų97.124%0.24348%0.481CS..SBendtrans-91151.2-179.1-55-170.4-176.7-1750110.7V190 L192 F193 N194 D199V190-K207 VanDerWaalsContact O-CE 3.3Å; V190-K207 WeakPolarHBondContact O-CE 3.26Å; V190-K207 PolarHBondContact O-NZ 3.29Å; L192-K207 CarbonylContact O-C 3.59Å; L192-K207 WeakPolarHBondContact O-CA 3.45Å; L192-K207 WeakPolarHBondContact O-CB 3.21Å; F193-K207 WeakPolarHBondContact O-CD 3.5Å; N194-K207 HydrophobicContact CB-CB 4.16Å; N194-K207 HydrophobicContact CB-CD 4.4Å; D199-K207 IonicContact OD1-NZ 2.86Å; D199-K207 PolarHBondContact OD1-NZ 3.49Å; D199-K207 IonicContact OD2-NZ 3.53Å; D199-K207 PolarHBondContact OD2-NZ 3.32Å
208L87.5Confident78.5Confident96 Ų96100.7 Ų100.750%0.50349%0.488SS..BIsolated β-bridgetrans-84.7142.3177.4-59.1174.9000110.3L192 F193 N194L192-L208 HydrophobicContact CD1-CD1 3.97Å; L192-L208 HydrophobicContact CD1-CG 4.46Å; L192-L208 HydrophobicContact CG-CD1 4.17Å; L192-L208 PolarHBondContact O-N 2.7Å; F193-L208 VanDerWaalsContact CA-O 3.29Å; F193-L208 WeakPolarHBondContact CA-O 3.29Å; F193-L208 HydrophobicContact CD1-CB 3.62Å; F193-L208 HydrophobicContact CE1-CB 3.76Å; F193-L208 HydrophobicContact CE1-CD1 4.11Å; N194-L208 PolarHBondContact N-O 3.08Å; N194-L208 VanDerWaalsContact N-O 3.08Å; N194-L208 PolarHBondContact OD1-O 3.48Å
209D89.4Confident77.7Confident28 Ų2897.7 Ų97.715%0.1548%0.483CS..  trans-121.999.1172.2-167.6-20.6000110.3N194 R211 R212N194-D209 PolarHBondContact ND2-OD2 2.86Å; N194-D209 WeakPolarHBondContact OD1-CA 3.39Å; N194-D209 VanDerWaalsContact OD1-CB 3.31Å; N194-D209 WeakPolarHBondContact OD1-CB 3.49Å; N194-D209 VanDerWaalsContact OD1-CG 3.24Å; N194-D209 PolarHBondContact OD1-OD2 3.48Å; D209-R211 VanDerWaalsContact CG-NH2 3.31Å; D209-R211 PolarHBondContact O-N 3.19Å; D209-R211 VanDerWaalsContact OD1-CB 3.27Å; D209-R211 WeakPolarHBondContact OD1-CB 3.28Å; D209-R211 IonicContact OD1-CZ 2.71Å; D209-R211 PolarHBondContact OD1-N 2.85Å; D209-R211 IonicContact OD1-NE 3.67Å; D209-R211 PolarHBondContact OD1-NE 3.14Å; D209-R211 IonicContact OD1-NH2 3.86Å; D209-R211 PolarHBondContact OD1-NH2 2.78Å; D209-R211 IonicContact OD2-CZ 2.72Å; D209-R211 IonicContact OD2-NE 2.71Å; D209-R211 PolarHBondContact OD2-NE 2.87Å; D209-R211 IonicContact OD2-NH2 3.98Å; D209-R211 PolarHBondContact OD2-NH2 3.11Å; D209-R212 PolarHBondContact O-N 3.43Å
210P88.4Confident77.1Confident78 Ų78101 Ų10151%0.50650%0.495SS..THydrogen-bonded Turntrans-68.3-12.9-178.5-22.436.1000114.2F193 F195 R212F193-P210 HydrophobicContact CD1-CG 3.59Å; F193-P210 HydrophobicContact CE1-CG 3.58Å; F195-P210 HydrophobicContact CZ-CG 3.88Å; P210-R212 PolarHBondContact O-N 3.11Å
211R86.3Confident76.8Confident113 Ų11399 Ų9943%0.42649%0.486SS..THydrogen-bonded Turntrans-70.8-13.3178.3-62.8168.2-70.7-149.7-13.4112.6N194 L201 D209N194-R211 PolarHBondContact ND2-NH2 3.43Å; N194-R211 PolarHBondContact OD1-NH2 3.45Å; N194-R211 VanDerWaalsContact OD1-NH2 3.1Å; L201-R211 VanDerWaalsContact CD2-CZ 3.5Å; D209-R211 VanDerWaalsContact CG-NH2 3.31Å; D209-R211 PolarHBondContact O-N 3.19Å; D209-R211 VanDerWaalsContact OD1-CB 3.27Å; D209-R211 WeakPolarHBondContact OD1-CB 3.28Å; D209-R211 IonicContact OD1-CZ 2.71Å; D209-R211 PolarHBondContact OD1-N 2.85Å; D209-R211 IonicContact OD1-NE 3.67Å; D209-R211 PolarHBondContact OD1-NE 3.14Å; D209-R211 IonicContact OD1-NH2 3.86Å; D209-R211 PolarHBondContact OD1-NH2 2.78Å; D209-R211 IonicContact OD2-CZ 2.72Å; D209-R211 IonicContact OD2-NE 2.71Å; D209-R211 PolarHBondContact OD2-NE 2.87Å; D209-R211 IonicContact OD2-NH2 3.98Å; D209-R211 PolarHBondContact OD2-NH2 3.11Å
212R77.7Confident76.7Confident107 Ų10795.4 Ų95.440%0.40447%0.468SS..SBendtrans-118.6133.4-179.2-60.8-177.9177.2168.77.2109.1L201 D209 P210 G214 I217L201-R212 VanDerWaalsContact O-CZ 3.24Å; L201-R212 PolarHBondContact O-NH1 3.1Å; L201-R212 PolarHBondContact O-NH2 3.25Å; D209-R212 PolarHBondContact O-N 3.43Å; P210-R212 PolarHBondContact O-N 3.11Å; R212-G214 PolarHBondContact O-N 2.97Å; R212-I217 HydrophobicContact CB-CD1 3.13Å; R212-I217 HydrophobicContact CB-CG1 3.57Å; R212-I217 HydrophobicContact CG-CD1 4.1Å; R212-I217 HydrophobicContact CG-CG1 4.39Å
213E72.6Confident77.1Confident135 Ų13589.9 Ų89.963%0.63146%0.456SS*.  trans-68.1119.9176.8-64.3-169.6175.500110.5A215 E216 I217E213-A215 PolarHBondContact O-N 3.46Å; E213-A215 VanDerWaalsContact O-N 3.1Å; E213-E216 HydrophobicContact CB-CB 4.22Å; E213-E216 HydrophobicContact CB-CG 4.12Å; E213-E216 PolarHBondContact O-N 3.14Å; E213-E216 VanDerWaalsContact O-N 3.11Å; E213-I217 WeakPolarHBondContact O-CG1 3.37Å; E213-I217 PolarHBondContact O-N 2.82Å; E213-I217 VanDerWaalsContact O-N 3.11Å
214G64.8Low77.8Confident44 Ų4488 Ų8845%0.45445%0.45SS..Hα-helixtrans-61.6-22.5-171.300000115.1R212 R218R212-G214 PolarHBondContact O-N 2.97Å; G214-R218 PolarHBondContact O-NE 3.47Å
215A62.2Low78.9Confident58 Ų5886 Ų8648%0.47944%0.438SS..Hα-helixtrans-81.1-43.7173.800000112E213 I217 R218 N219E213-A215 PolarHBondContact O-N 3.46Å; E213-A215 VanDerWaalsContact O-N 3.1Å; A215-I217 PolarHBondContact O-N 2.87Å; A215-R218 PolarHBondContact O-N 3.3Å; A215-N219 PolarHBondContact O-N 3.15Å; A215-N219 VanDerWaalsContact O-N 3.15Å
216E65.4Low80.3Confident89 Ų8982.2 Ų82.242%0.41640%0.404SS..Hα-helixtrans-64.5-38.6179.4-70.4-157.1155.900113E213 N219 K220E213-E216 HydrophobicContact CB-CB 4.22Å; E213-E216 HydrophobicContact CB-CG 4.12Å; E213-E216 PolarHBondContact O-N 3.14Å; E213-E216 VanDerWaalsContact O-N 3.11Å; E216-N219 PolarHBondContact O-N 3.37Å; E216-K220 VanDerWaalsContact O-CB 3.29Å; E216-K220 WeakPolarHBondContact O-CB 3.41Å; E216-K220 VanDerWaalsContact O-CG 3.26Å; E216-K220 WeakPolarHBondContact O-CG 3.42Å; E216-K220 PolarHBondContact O-N 3.36Å; E216-K220 IonicContact OE2-NZ 3.49Å; E216-K220 PolarHBondContact OE2-NZ 3.4Å
217I67.8Low81Confident55 Ų5576.9 Ų76.928%0.28239%0.387SS..Hα-helixtrans-62.1-49.3179.5-58.2162.3000110R212 E213 A215 N219 K220 T221R212-I217 HydrophobicContact CB-CD1 3.13Å; R212-I217 HydrophobicContact CB-CG1 3.57Å; R212-I217 HydrophobicContact CG-CD1 4.1Å; R212-I217 HydrophobicContact CG-CG1 4.39Å; E213-I217 WeakPolarHBondContact O-CG1 3.37Å; E213-I217 PolarHBondContact O-N 2.82Å; E213-I217 VanDerWaalsContact O-N 3.11Å; A215-I217 PolarHBondContact O-N 2.87Å; I217-N219 VanDerWaalsContact C-N 3.3Å; I217-N219 PolarHBondContact O-N 2.93Å; I217-K220 PolarHBondContact O-N 3Å; I217-T221 HydrophobicContact CG2-CG2 4.15Å; I217-T221 WeakPolarHBondContact O-CG2 3.24Å; I217-T221 PolarHBondContact O-N 2.81Å; I217-T221 PolarHBondContact O-OG1 2.94Å
218R70.3Confident81.2Confident162 Ų16274.4 Ų74.461%0.61138%0.378SS*.Hα-helixtrans-58-47-179.2-75.7-177.6-77175.3-0.9109.9G214 A215 K220 T221 V222G214-R218 PolarHBondContact O-NE 3.47Å; A215-R218 PolarHBondContact O-N 3.3Å; R218-K220 PolarHBondContact O-N 3.39Å; R218-T221 PolarHBondContact O-N 3.04Å; R218-T221 PolarHBondContact O-OG1 3Å; R218-V222 WeakPolarHBondContact O-CB 3.5Å; R218-V222 WeakPolarHBondContact O-CG2 3.41Å; R218-V222 PolarHBondContact O-N 2.98Å
219N77.4Confident81.5Confident107 Ų10769.9 Ų69.957%0.57235%0.354SS*.Hα-helixtrans-64.4-43.3177.8-66.8-12.3000112.1A215 E216 I217 V222 V223A215-N219 PolarHBondContact O-N 3.15Å; A215-N219 VanDerWaalsContact O-N 3.15Å; E216-N219 PolarHBondContact O-N 3.37Å; I217-N219 VanDerWaalsContact C-N 3.3Å; I217-N219 PolarHBondContact O-N 2.93Å; N219-V222 PolarHBondContact O-N 3.5Å; N219-V223 WeakPolarHBondContact O-CB 3.49Å; N219-V223 WeakPolarHBondContact O-CG2 3.33Å; N219-V223 PolarHBondContact O-N 3.36Å
220K81.3Confident81.7Confident117 Ų11774.3 Ų74.351%0.50937%0.369SS..Hα-helixtrans-63.4-41.8177.8-76.9167.6178.5160.40111.9E216 I217 R218 N224E216-K220 VanDerWaalsContact O-CB 3.29Å; E216-K220 WeakPolarHBondContact O-CB 3.41Å; E216-K220 VanDerWaalsContact O-CG 3.26Å; E216-K220 WeakPolarHBondContact O-CG 3.42Å; E216-K220 PolarHBondContact O-N 3.36Å; E216-K220 IonicContact OE2-NZ 3.49Å; E216-K220 PolarHBondContact OE2-NZ 3.4Å; I217-K220 PolarHBondContact O-N 3Å; R218-K220 PolarHBondContact O-N 3.39Å; K220-N224 WeakPolarHBondContact O-CB 3.35Å; K220-N224 PolarHBondContact O-N 3.22Å; K220-N224 PolarHBondContact O-ND2 2.86Å; K220-N224 PolarHBondContact O-OD1 3.37Å
221T82.8Confident81.9Confident38 Ų3873.4 Ų73.423%0.23337%0.365CS..Hα-helixtrans-67.7-4317851.40000111.5I217 R218 N224 L225 M245I217-T221 HydrophobicContact CG2-CG2 4.15Å; I217-T221 WeakPolarHBondContact O-CG2 3.24Å; I217-T221 PolarHBondContact O-N 2.81Å; I217-T221 PolarHBondContact O-OG1 2.94Å; R218-T221 PolarHBondContact O-N 3.04Å; R218-T221 PolarHBondContact O-OG1 3Å; T221-N224 PolarHBondContact O-N 3.27Å; T221-L225 WeakPolarHBondContact O-CB 3.47Å; T221-L225 PolarHBondContact O-N 3.2Å; T221-M245 HydrophobicContact CG2-CE 4.14Å
222V85.4Confident82.3Confident11 Ų1169.1 Ų69.17%0.06736%0.356CS..Hα-helixtrans-61.5-48.7175.7173.10000110.9R218 N219 N224 L225 L226 Q249 D251R218-V222 WeakPolarHBondContact O-CB 3.5Å; R218-V222 WeakPolarHBondContact O-CG2 3.41Å; R218-V222 PolarHBondContact O-N 2.98Å; N219-V222 PolarHBondContact O-N 3.5Å; V222-N224 VanDerWaalsContact C-N 3.31Å; V222-N224 PolarHBondContact O-N 2.88Å; V222-L225 WeakPolarHBondContact O-CB 3.29Å; V222-L225 PolarHBondContact O-N 2.94Å; V222-L225 VanDerWaalsContact O-N 3.15Å; V222-L226 HydrophobicContact CG1-CD1 4.07Å; V222-L226 HydrophobicContact CG1-CG 4.3Å; V222-L226 WeakPolarHBondContact O-CG 3.38Å; V222-L226 PolarHBondContact O-N 3.11Å; V222-Q249 HydrophobicContact CG2-CB 3.58Å; V222-Q249 HydrophobicContact CG2-CG 4.32Å; V222-D251 HydrophobicContact CG1-CB 4.24Å
223V87.4Confident83Confident86 Ų8666.9 Ų66.952%0.52135%0.352SS..Hα-helixtrans-59.5-43.2178.6169.30000111N219 L225 L226 F227N219-V223 WeakPolarHBondContact O-CB 3.49Å; N219-V223 WeakPolarHBondContact O-CG2 3.33Å; N219-V223 PolarHBondContact O-N 3.36Å; V223-L225 VanDerWaalsContact C-N 3.34Å; V223-L225 PolarHBondContact O-N 3.28Å; V223-L226 PolarHBondContact O-N 3.39Å; V223-F227 VanDerWaalsContact O-CB 3.28Å; V223-F227 WeakPolarHBondContact O-CB 3.3Å; V223-F227 PolarHBondContact O-N 3.27Å
224N89.6Confident84Confident91 Ų9161.1 Ų61.149%0.48733%0.326SS..Hα-helixtrans-64.9-38177.4-69.8-17.8000112.5K220 T221 V222 A228 F240K220-N224 WeakPolarHBondContact O-CB 3.35Å; K220-N224 PolarHBondContact O-N 3.22Å; K220-N224 PolarHBondContact O-ND2 2.86Å; K220-N224 PolarHBondContact O-OD1 3.37Å; T221-N224 PolarHBondContact O-N 3.27Å; V222-N224 VanDerWaalsContact C-N 3.31Å; V222-N224 PolarHBondContact O-N 2.88Å; N224-A228 PolarHBondContact O-N 3.22Å; N224-A228 VanDerWaalsContact O-N 3.14Å; N224-F240 HydrophobicContact CB-CZ 4.21Å
225L91.4Very high85.3Confident0 Ų062.6 Ų62.60%033%0.329CS..Hα-helixtrans-63.1-48.7175.417667.7000111T221 V222 V223 A228 A229 L237 F240 M245 M247 A257T221-L225 WeakPolarHBondContact O-CB 3.47Å; T221-L225 PolarHBondContact O-N 3.2Å; V222-L225 WeakPolarHBondContact O-CB 3.29Å; V222-L225 PolarHBondContact O-N 2.94Å; V222-L225 VanDerWaalsContact O-N 3.15Å; V223-L225 VanDerWaalsContact C-N 3.34Å; V223-L225 PolarHBondContact O-N 3.28Å; L225-A228 WeakPolarHBondContact O-CB 3.45Å; L225-A228 PolarHBondContact O-N 3.12Å; L225-A229 PolarHBondContact O-N 3.45Å; L225-L237 HydrophobicContact CD1-CD2 3.55Å; L225-F240 HydrophobicContact CD1-CB 4.23Å; L225-F240 HydrophobicContact CD1-CD2 3.9Å; L225-F240 HydrophobicContact CD1-CG 4.37Å; L225-M245 HydrophobicContact CB-SD 4.4Å; L225-M247 HydrophobicContact CD1-CE 3.61Å; L225-M247 HydrophobicContact CD1-SD 3.72Å; L225-M247 HydrophobicContact CD2-SD 4.45Å; L225-A257 HydrophobicContact CD2-CB 4.49Å; L225-A257 HydrophobicContact CG-CB 4.33Å
226L91.3Very high86.7Confident14 Ų1460.3 Ų60.37%0.07331%0.31CS..Hα-helixtrans-68.1-36180-64.4-174.8000112.5V222 V223 A228 A229 Y230 D251 T256 A257 V260V222-L226 HydrophobicContact CG1-CD1 4.07Å; V222-L226 HydrophobicContact CG1-CG 4.3Å; V222-L226 WeakPolarHBondContact O-CG 3.38Å; V222-L226 PolarHBondContact O-N 3.11Å; V223-L226 PolarHBondContact O-N 3.39Å; L226-A228 VanDerWaalsContact C-N 3.31Å; L226-A228 PolarHBondContact O-N 3.43Å; L226-A229 WeakPolarHBondContact O-CB 3.24Å; L226-A229 PolarHBondContact O-N 2.92Å; L226-A229 VanDerWaalsContact O-N 3.14Å; L226-Y230 PolarHBondContact O-N 2.67Å; L226-D251 HydrophobicContact CD1-CB 3.48Å; L226-D251 VanDerWaalsContact CD1-CB 3.48Å; L226-T256 VanDerWaalsContact CD2-C 3.41Å; L226-A257 HydrophobicContact CD2-CB 3.97Å; L226-V260 HydrophobicContact CB-CG2 4.41Å; L226-V260 HydrophobicContact CD1-CG2 4.48Å; L226-V260 HydrophobicContact CD2-CG2 4.05Å
227F93.2Very high87.9Confident129 Ų12956.1 Ų56.157%0.56629%0.291SS*.Hα-helixtrans-64.9-35.9175.2-174.8-98.5000112.2V223 A229 Y230 S231V223-F227 VanDerWaalsContact O-CB 3.28Å; V223-F227 WeakPolarHBondContact O-CB 3.3Å; V223-F227 PolarHBondContact O-N 3.27Å; F227-A229 VanDerWaalsContact C-N 3.32Å; F227-Y230 HydrophobicContact CD2-CD1 4.38Å; F227-Y230 HydrophobicContact CE2-CD1 4.29Å; F227-Y230 PolarHBondContact O-N 2.88Å; F227-S231 WeakPolarHBondContact O-CB 3.43Å; F227-S231 PolarHBondContact O-N 3.33Å; F227-S231 PolarHBondContact O-OG 2.95Å
228A93.5Very high89Confident5 Ų560.1 Ų60.14%0.04130%0.302CS..Hα-helixtrans-64.1-38.4171.800000111.7N224 L225 L226 S231 G232 D233 A236 L237 F240N224-A228 PolarHBondContact O-N 3.22Å; N224-A228 VanDerWaalsContact O-N 3.14Å; L225-A228 WeakPolarHBondContact O-CB 3.45Å; L225-A228 PolarHBondContact O-N 3.12Å; L226-A228 VanDerWaalsContact C-N 3.31Å; L226-A228 PolarHBondContact O-N 3.43Å; A228-S231 PolarHBondContact O-OG 3.42Å; A228-G232 PolarHBondContact O-N 3.27Å; A228-D233 PolarHBondContact O-N 3.07Å; A228-A236 HydrophobicContact CB-CB 3.83Å; A228-L237 HydrophobicContact CB-CD2 3.84Å; A228-L237 HydrophobicContact CB-CG 4.09Å; A228-F240 HydrophobicContact CB-CE2 4.18Å
229A93.2Very high89.9Confident0 Ų060 Ų600%030%0.302CS..Hα-helixtrans-66.6-41.2174.100000112.5L225 L226 F227 G232 A257 V260 A261 H266 V269L225-A229 PolarHBondContact O-N 3.45Å; L226-A229 WeakPolarHBondContact O-CB 3.24Å; L226-A229 PolarHBondContact O-N 2.92Å; L226-A229 VanDerWaalsContact O-N 3.14Å; F227-A229 VanDerWaalsContact C-N 3.32Å; A229-G232 PolarHBondContact O-N 3.09Å; A229-A257 HydrophobicContact CB-CB 4.22Å; A229-V260 HydrophobicContact CB-CB 4.41Å; A229-V260 HydrophobicContact CB-CG1 4.4Å; A229-A261 HydrophobicContact CB-CB 4.39Å; A229-H266 PolarHBondContact O-CD2 3.04Å; A229-H266 VanDerWaalsContact O-CD2 3.26Å; A229-V269 HydrophobicContact CB-CG1 4.29Å
230Y94.1Very high90.4Very high121 Ų12157.2 Ų57.248%0.47529%0.285SS..Hα-helixtrans-63-42.6176.3170.2-98.5000112.9L226 F227 G232 E264 H266L226-Y230 PolarHBondContact O-N 2.67Å; F227-Y230 HydrophobicContact CD2-CD1 4.38Å; F227-Y230 HydrophobicContact CE2-CD1 4.29Å; F227-Y230 PolarHBondContact O-N 2.88Å; Y230-G232 VanDerWaalsContact C-N 3.3Å; Y230-G232 PolarHBondContact O-N 3.5Å; Y230-E264 HydrophobicContact CD2-CG 3.7Å; Y230-E264 WeakPolarHBondContact CD2-OE1 3.49Å; Y230-E264 VanDerWaalsContact CE2-CD 3.47Å; Y230-E264 HydrophobicContact CE2-CG 4.2Å; Y230-E264 WeakPolarHBondContact CE2-OE1 3.31Å; Y230-H266 PolarHBondContact O-CD2 3.09Å; Y230-H266 PolarHBondContact O-NE2 3.19Å
231S93.3Very high90.7Very high60 Ų6053.2 Ų53.242%0.4227%0.274SS..Hα-helixtrans-79.6-8.9-179.4530000114.4F227 A228 D233F227-S231 WeakPolarHBondContact O-CB 3.43Å; F227-S231 PolarHBondContact O-N 3.33Å; F227-S231 PolarHBondContact O-OG 2.95Å; A228-S231 PolarHBondContact O-OG 3.42Å; S231-D233 VanDerWaalsContact C-N 3.34Å
232G92.8Very high90.9Very high22 Ų2258.7 Ų58.723%0.22730%0.301CS..THydrogen-bonded Turntrans76.614.7-175.400000114.4A228 A229 Y230 V234A228-G232 PolarHBondContact O-N 3.27Å; A229-G232 PolarHBondContact O-N 3.09Å; Y230-G232 VanDerWaalsContact C-N 3.3Å; Y230-G232 PolarHBondContact O-N 3.5Å; G232-V234 PolarHBondContact O-N 3.33Å
233D93.8Very high90.8Very high60 Ų6060.4 Ų60.432%0.32131%0.313SS..  trans-79.385.8-177.6-173.6-3.5000111.9A228 S231 S235 A236 L237 R239A228-D233 PolarHBondContact O-N 3.07Å; S231-D233 VanDerWaalsContact C-N 3.34Å; D233-S235 PolarHBondContact O-N 3.2Å; D233-S235 WeakPolarHBondContact OD1-CA 3.48Å; D233-S235 VanDerWaalsContact OD1-CB 3.24Å; D233-S235 WeakPolarHBondContact OD1-CB 3.5Å; D233-S235 PolarHBondContact OD1-N 3.09Å; D233-A236 HydrophobicContact CB-CB 4.1Å; D233-A236 PolarHBondContact O-N 2.91Å; D233-A236 PolarHBondContact OD1-N 3.12Å; D233-A236 VanDerWaalsContact OD2-CB 3.3Å; D233-A236 WeakPolarHBondContact OD2-CB 3.3Å; D233-L237 PolarHBondContact O-N 2.95Å; D233-R239 IonicContact OD2-NH2 3.42Å
234V92.8Very high90.4Very high15 Ų1560.3 Ų60.39%0.09132%0.322CS..Hα-helixtrans-60.7-29.6174.6-175.20000111.7G232 L237 R238 E268 V269 F272G232-V234 PolarHBondContact O-N 3.33Å; V234-L237 PolarHBondContact O-N 3.28Å; V234-R238 HydrophobicContact CG1-CG 4.32Å; V234-R238 WeakPolarHBondContact O-CB 3.44Å; V234-R238 VanDerWaalsContact O-CG 3.3Å; V234-R238 WeakPolarHBondContact O-CG 3.43Å; V234-R238 PolarHBondContact O-N 2.88Å; V234-E268 HydrophobicContact CG2-CB 3.72Å; V234-V269 HydrophobicContact CG2-CG2 3.78Å; V234-F272 HydrophobicContact CG1-CB 4.34Å; V234-F272 HydrophobicContact CG1-CG 4.37Å
235S92.7Very high90.1Very high75 Ų7557.9 Ų57.952%0.52431%0.308SS..Hα-helixtrans-69.1-40.7-179.9-60.10000111.2D233 R239D233-S235 PolarHBondContact O-N 3.2Å; D233-S235 WeakPolarHBondContact OD1-CA 3.48Å; D233-S235 VanDerWaalsContact OD1-CB 3.24Å; D233-S235 WeakPolarHBondContact OD1-CB 3.5Å; D233-S235 PolarHBondContact OD1-N 3.09Å; S235-R239 WeakPolarHBondContact O-CG 3.2Å; S235-R239 PolarHBondContact O-N 2.82Å; S235-R239 VanDerWaalsContact O-N 3.11Å
236A90.8Very high89.8Confident10 Ų1062 Ų628%0.08333%0.33CS..Hα-helixtrans-62.4-45.1171.600000111.9A228 D233 R238 R239 F240A228-A236 HydrophobicContact CB-CB 3.83Å; D233-A236 HydrophobicContact CB-CB 4.1Å; D233-A236 PolarHBondContact O-N 2.91Å; D233-A236 PolarHBondContact OD1-N 3.12Å; D233-A236 VanDerWaalsContact OD2-CB 3.3Å; D233-A236 WeakPolarHBondContact OD2-CB 3.3Å; A236-R238 PolarHBondContact O-N 3.15Å; A236-R239 WeakPolarHBondContact O-CB 3.35Å; A236-R239 PolarHBondContact O-N 3.43Å; A236-R239 VanDerWaalsContact O-N 3.12Å; A236-F240 HydrophobicContact CB-CE2 4.29Å; A236-F240 VanDerWaalsContact O-CD2 3.24Å; A236-F240 WeakPolarHBondContact O-CD2 3.48Å; A236-F240 WeakPolarHBondContact O-CG 3.36Å; A236-F240 PolarHBondContact O-N 2.86Å
237L90.4Very high89.6Confident0 Ų061.9 Ų61.90%033%0.329CS..Hα-helixtrans-62.6-40.7177.8-65.6177.3000112.7L225 A228 D233 V234 R239 F240 A241 M247 V269 F272L225-L237 HydrophobicContact CD1-CD2 3.55Å; A228-L237 HydrophobicContact CB-CD2 3.84Å; A228-L237 HydrophobicContact CB-CG 4.09Å; D233-L237 PolarHBondContact O-N 2.95Å; V234-L237 PolarHBondContact O-N 3.28Å; L237-R239 VanDerWaalsContact C-N 3.32Å; L237-R239 PolarHBondContact O-N 2.86Å; L237-F240 HydrophobicContact CD2-CD2 4.49Å; L237-F240 PolarHBondContact O-N 3.14Å; L237-A241 WeakPolarHBondContact O-CB 3.42Å; L237-A241 PolarHBondContact O-N 2.87Å; L237-M247 HydrophobicContact CD2-CE 4.18Å; L237-V269 HydrophobicContact CD1-CB 4.14Å; L237-V269 HydrophobicContact CD1-CG1 3.33Å; L237-V269 HydrophobicContact CD1-CG2 3.91Å; L237-F272 HydrophobicContact CB-CD1 3.92Å; L237-F272 HydrophobicContact CB-CE1 3.77Å
238R91.4Very high89.4Confident139 Ų13959.8 Ų59.853%0.52532%0.321SS..Hα-helixtrans-58.9-42.6172.2-75.6175.7-170.3-88-0.4111.8V234 A236 L242 F272V234-R238 HydrophobicContact CG1-CG 4.32Å; V234-R238 WeakPolarHBondContact O-CB 3.44Å; V234-R238 VanDerWaalsContact O-CG 3.3Å; V234-R238 WeakPolarHBondContact O-CG 3.43Å; V234-R238 PolarHBondContact O-N 2.88Å; A236-R238 PolarHBondContact O-N 3.15Å; R238-L242 WeakPolarHBondContact O-CB 3.22Å; R238-L242 WeakPolarHBondContact O-CD1 3.42Å; R238-L242 VanDerWaalsContact O-CG 3.22Å; R238-L242 WeakPolarHBondContact O-CG 3.36Å; R238-L242 PolarHBondContact O-N 3.41Å; R238-F272 HydrophobicContact CB-CE2 4.46Å; R238-F272 HydrophobicContact CB-CZ 4.32Å; R238-F272 HydrophobicContact CG-CD2 4.03Å; R238-F272 HydrophobicContact CG-CE2 3.48Å; R238-F272 VanDerWaalsContact CG-CE2 3.48Å; R238-F272 HydrophobicContact CG-CZ 3.76Å
239R89.1Confident89.1Confident159 Ų15961.9 Ų61.960%0.633%0.33SS*.Hα-helixtrans-63.8-41175.9-71.9-177.4-64.8-138.7-2.8112.1D233 S235 A236 L237 L242 S243D233-R239 IonicContact OD2-NH2 3.42Å; S235-R239 WeakPolarHBondContact O-CG 3.2Å; S235-R239 PolarHBondContact O-N 2.82Å; S235-R239 VanDerWaalsContact O-N 3.11Å; A236-R239 WeakPolarHBondContact O-CB 3.35Å; A236-R239 PolarHBondContact O-N 3.43Å; A236-R239 VanDerWaalsContact O-N 3.12Å; L237-R239 VanDerWaalsContact C-N 3.32Å; L237-R239 PolarHBondContact O-N 2.86Å; R239-L242 PolarHBondContact O-N 3.4Å; R239-S243 PolarHBondContact O-N 3.46Å; R239-S243 VanDerWaalsContact O-N 3.09Å
240F88.1Confident88.9Confident49 Ų4966.8 Ų66.822%0.21535%0.351CS..Hα-helixtrans-65.6-46.4177-66.8-46.6000112N224 L225 A228 A236 L237 L242 S243 M245 M247N224-F240 HydrophobicContact CB-CZ 4.21Å; L225-F240 HydrophobicContact CD1-CB 4.23Å; L225-F240 HydrophobicContact CD1-CD2 3.9Å; L225-F240 HydrophobicContact CD1-CG 4.37Å; A228-F240 HydrophobicContact CB-CE2 4.18Å; A236-F240 HydrophobicContact CB-CE2 4.29Å; A236-F240 VanDerWaalsContact O-CD2 3.24Å; A236-F240 WeakPolarHBondContact O-CD2 3.48Å; A236-F240 WeakPolarHBondContact O-CG 3.36Å; A236-F240 PolarHBondContact O-N 2.86Å; L237-F240 HydrophobicContact CD2-CD2 4.49Å; L237-F240 PolarHBondContact O-N 3.14Å; F240-L242 VanDerWaalsContact C-N 3.35Å; F240-L242 PolarHBondContact O-N 2.91Å; F240-S243 PolarHBondContact O-N 2.96Å; F240-S243 PolarHBondContact O-OG 3.43Å; F240-M245 HydrophobicContact CB-CB 4.43Å; F240-M245 HydrophobicContact CB-SD 4.1Å; F240-M245 HydrophobicContact CD1-CE 3.74Å; F240-M245 HydrophobicContact CD1-SD 4.11Å; F240-M245 HydrophobicContact CE1-CE 4.27Å; F240-M245 HydrophobicContact CG-CE 4.39Å; F240-M245 HydrophobicContact CG-SD 4.17Å; F240-M245 WeakPolarHBondContact O-CB 3.17Å; F240-M245 PolarHBondContact O-N 3.33Å; F240-M247 HydrophobicContact CB-SD 4.36Å
241A87.4Confident88.7Confident34 Ų3462.1 Ų62.128%0.28133%0.334SS..Hα-helixtrans-59.7-43.4175.700000112.1L237 S243 A244 M247 F272L237-A241 WeakPolarHBondContact O-CB 3.42Å; L237-A241 PolarHBondContact O-N 2.87Å; A241-S243 PolarHBondContact O-N 3.26Å; A241-A244 PolarHBondContact O-N 3.04Å; A241-A244 VanDerWaalsContact O-N 3.11Å; A241-M247 HydrophobicContact CB-SD 4.38Å; A241-F272 HydrophobicContact CB-CE1 4.23Å; A241-F272 HydrophobicContact CB-CZ 3.77Å
242L87.3Confident88.3Confident153 Ų15367.3 Ų67.380%0.80135%0.346SS*.Hα-helixtrans-63.6-26.2175.2-75168.7000113.2R238 R239 F240 A244R238-L242 WeakPolarHBondContact O-CB 3.22Å; R238-L242 WeakPolarHBondContact O-CD1 3.42Å; R238-L242 VanDerWaalsContact O-CG 3.22Å; R238-L242 WeakPolarHBondContact O-CG 3.36Å; R238-L242 PolarHBondContact O-N 3.41Å; R239-L242 PolarHBondContact O-N 3.4Å; F240-L242 VanDerWaalsContact C-N 3.35Å; F240-L242 PolarHBondContact O-N 2.91Å; L242-A244 PolarHBondContact O-N 2.9Å
243S82.8Confident88.1Confident46 Ų4666.7 Ų66.732%0.32234%0.337SS..THydrogen-bonded Turntrans-80.38.5176.1730000114.2R239 F240 A241 M245R239-S243 PolarHBondContact O-N 3.46Å; R239-S243 VanDerWaalsContact O-N 3.09Å; F240-S243 PolarHBondContact O-N 2.96Å; F240-S243 PolarHBondContact O-OG 3.43Å; A241-S243 PolarHBondContact O-N 3.26Å; S243-M245 PolarHBondContact O-N 3.17Å
244A80.3Confident87.9Confident85 Ų8566.1 Ų66.170%0.70234%0.338SS*.THydrogen-bonded Turntrans56.931.9-174.400000113.1A241 L242A241-A244 PolarHBondContact O-N 3.04Å; A241-A244 VanDerWaalsContact O-N 3.11Å; L242-A244 PolarHBondContact O-N 2.9Å
245M82.6Confident87.9Confident39 Ų3968.8 Ų68.819%0.19235%0.347CS..  trans-70.6136.7170.1-172.9173.2-68.100109T221 L225 F240 S243 M247T221-M245 HydrophobicContact CG2-CE 4.14Å; L225-M245 HydrophobicContact CB-SD 4.4Å; F240-M245 HydrophobicContact CB-CB 4.43Å; F240-M245 HydrophobicContact CB-SD 4.1Å; F240-M245 HydrophobicContact CD1-CE 3.74Å; F240-M245 HydrophobicContact CD1-SD 4.11Å; F240-M245 HydrophobicContact CE1-CE 4.27Å; F240-M245 HydrophobicContact CG-CE 4.39Å; F240-M245 HydrophobicContact CG-SD 4.17Å; F240-M245 WeakPolarHBondContact O-CB 3.17Å; F240-M245 PolarHBondContact O-N 3.33Å; S243-M245 PolarHBondContact O-N 3.17Å; M245-M247 PolarHBondContact O-N 3.11Å
246D85.6Confident87.8Confident87 Ų8765.3 Ų65.347%0.46532%0.322SS..  trans-69.8117.3171.1177.713.5000109.4E248 Q249D246-E248 VanDerWaalsContact C-N 3.3Å; D246-E248 PolarHBondContact OD1-N 3.31Å; D246-Q249 HydrophobicContact CB-CG 4.02Å; D246-Q249 VanDerWaalsContact O-CG 3.29Å; D246-Q249 WeakPolarHBondContact O-CG 3.38Å
247M86.4Confident87.9Confident11 Ų1164.9 Ų64.95%0.05432%0.318CS..THydrogen-bonded Turntrans-84-8.2-176.1-58.9-66.7-71.500112.2L225 L237 F240 A241 M245 Q249 F272 L273 C277 V279L225-M247 HydrophobicContact CD1-CE 3.61Å; L225-M247 HydrophobicContact CD1-SD 3.72Å; L225-M247 HydrophobicContact CD2-SD 4.45Å; L237-M247 HydrophobicContact CD2-CE 4.18Å; F240-M247 HydrophobicContact CB-SD 4.36Å; A241-M247 HydrophobicContact CB-SD 4.38Å; M245-M247 PolarHBondContact O-N 3.11Å; M247-Q249 VanDerWaalsContact C-N 3.31Å; M247-F272 HydrophobicContact CE-CE1 4.33Å; M247-L273 HydrophobicContact CE-CD2 3.53Å; M247-C277 HydrophobicContact CB-CB 4.27Å; M247-C277 HydrophobicContact CG-CB 4.15Å; M247-V279 HydrophobicContact CB-CG2 4Å
248E88.4Confident88.1Confident86 Ų8664.9 Ų64.940%0.40232%0.318SS..THydrogen-bonded Turntrans-90.24.2177.3-54.1-157.4130.500113.1D246 V279 N280D246-E248 VanDerWaalsContact C-N 3.3Å; D246-E248 PolarHBondContact OD1-N 3.31Å; E248-V279 HydrophobicContact CG-CG1 4.31Å; E248-N280 WeakPolarHBondContact OE1-CB 3.42Å; E248-N280 PolarHBondContact OE1-N 3.06Å
249Q87.6Confident88.2Confident48 Ų4858.3 Ų58.322%0.22429%0.293CS..  trans-61.4141.5177.8-65.7177.89.200111.5V222 D246 M247V222-Q249 HydrophobicContact CG2-CB 3.58Å; V222-Q249 HydrophobicContact CG2-CG 4.32Å; D246-Q249 HydrophobicContact CB-CG 4.02Å; D246-Q249 VanDerWaalsContact O-CG 3.29Å; D246-Q249 WeakPolarHBondContact O-CG 3.38Å; M247-Q249 VanDerWaalsContact C-N 3.31Å
250K89.8Confident88.4Confident103 Ų10351.5 Ų51.545%0.44827%0.27SS..  trans-110.5145-173.7-61.2-178.7178.6-165.40111.8S254 R255 T256K250-S254 WeakPolarHBondContact CD-O 3.47Å; K250-R255 VanDerWaalsContact CA-O 3.31Å; K250-R255 WeakPolarHBondContact CA-O 3.38Å; K250-T256 HydrophobicContact CG-CG2 3.87Å
251D89.1Confident88.7Confident23 Ų2349.1 Ų49.112%0.12326%0.259CS..  trans-77.9-172.2169.769.21.4000113.2V222 L226 D253 S254 R255V222-D251 HydrophobicContact CG1-CB 4.24Å; L226-D251 HydrophobicContact CD1-CB 3.48Å; L226-D251 VanDerWaalsContact CD1-CB 3.48Å; D251-D253 PolarHBondContact O-N 3.03Å; D251-D253 WeakPolarHBondContact OD1-CA 3.5Å; D251-D253 PolarHBondContact OD1-N 2.71Å; D251-S254 PolarHBondContact O-N 2.95Å; D251-S254 PolarHBondContact OD1-N 3.26Å; D251-S254 VanDerWaalsContact OD1-N 3.17Å; D251-R255 PolarHBondContact N-O 3.42Å; D251-R255 WeakPolarHBondContact OD1-CB 3.36Å; D251-R255 PolarHBondContact OD1-N 2.67Å; D251-R255 IonicContact OD1-NE 3.98Å; D251-R255 IonicContact OD2-CZ 3.48Å; D251-R255 IonicContact OD2-NE 2.8Å; D251-R255 PolarHBondContact OD2-NE 3.25Å; D251-R255 IonicContact OD2-NH2 3.26Å; D251-R255 PolarHBondContact OD2-NH2 2.82Å
252Y85.5Confident89Confident170 Ų17047.5 Ų47.567%0.66725%0.246SC*.THydrogen-bonded Turntrans-60-26.8176.469.5-83000112.9S254 R286Y252-S254 VanDerWaalsContact C-N 3.29Å; Y252-R286 PolarHBondContact O-NH2 2.89Å
253D89.3Confident89.3Confident8 Ų841.1 Ų41.14%0.04322%0.215CC..THydrogen-bonded Turntrans-92.112.8176.4-69.4-29.7000112.6D251 R255 R286 W287D251-D253 PolarHBondContact O-N 3.03Å; D251-D253 WeakPolarHBondContact OD1-CA 3.5Å; D251-D253 PolarHBondContact OD1-N 2.71Å; D253-R255 HydrophobicContact CB-CG 4.17Å; D253-R255 PolarHBondContact O-N 2.93Å; D253-R255 IonicContact OD2-NH2 2.93Å; D253-R286 WeakPolarHBondContact O-CB 3.35Å; D253-R286 PolarHBondContact O-N 3.44Å; D253-R286 IonicContact OD1-CZ 3.38Å; D253-R286 IonicContact OD1-NE 3.25Å; D253-R286 IonicContact OD1-NH1 2.74Å; D253-R286 PolarHBondContact OD1-NH1 2.82Å; D253-R286 IonicContact OD1-NH2 3.95Å; D253-R286 PolarHBondContact OD1-NH2 3.42Å; D253-W287 HydrophobicContact CB-CH2 4.08Å; D253-W287 HydrophobicContact CB-CZ3 3.91Å
254S89.7Confident89.8Confident48 Ų4843 Ų4334%0.33622%0.218SC..SBendtrans62.218.3-176.8-59.80000114.3K250 D251 Y252K250-S254 WeakPolarHBondContact CD-O 3.47Å; D251-S254 PolarHBondContact O-N 2.95Å; D251-S254 PolarHBondContact OD1-N 3.26Å; D251-S254 VanDerWaalsContact OD1-N 3.17Å; Y252-S254 VanDerWaalsContact C-N 3.29Å
255R90.8Very high90.4Very high72 Ų7239.7 Ų39.727%0.27219%0.193SC..  trans-87.3137.6-179.9-64.4-180-58.61703.9111.1K250 D251 D253 H259 D285K250-R255 VanDerWaalsContact CA-O 3.31Å; K250-R255 WeakPolarHBondContact CA-O 3.38Å; D251-R255 PolarHBondContact N-O 3.42Å; D251-R255 WeakPolarHBondContact OD1-CB 3.36Å; D251-R255 PolarHBondContact OD1-N 2.67Å; D251-R255 IonicContact OD1-NE 3.98Å; D251-R255 IonicContact OD2-CZ 3.48Å; D251-R255 IonicContact OD2-NE 2.8Å; D251-R255 PolarHBondContact OD2-NE 3.25Å; D251-R255 IonicContact OD2-NH2 3.26Å; D251-R255 PolarHBondContact OD2-NH2 2.82Å; D253-R255 HydrophobicContact CB-CG 4.17Å; D253-R255 PolarHBondContact O-N 2.93Å; D253-R255 IonicContact OD2-NH2 2.93Å; R255-H259 HydrophobicContact CB-CB 4Å; R255-H259 HydrophobicContact CG-CB 4.28Å; R255-D285 HydrophobicContact CG-CB 3.77Å
256T92.1Very high91Very high2 Ų240.7 Ų40.71%0.01220%0.197CC..  trans-92.3170.9172.463.90000111L226 K250 L258 H259 V260 A283L226-T256 VanDerWaalsContact CD2-C 3.41Å; K250-T256 HydrophobicContact CG-CG2 3.87Å; T256-L258 PolarHBondContact O-N 3.17Å; T256-L258 VanDerWaalsContact O-N 3.13Å; T256-L258 PolarHBondContact OG1-N 3.01Å; T256-H259 PolarHBondContact N-ND1 3.24Å; T256-H259 VanDerWaalsContact N-ND1 3.13Å; T256-H259 WeakPolarHBondContact O-CB 3.21Å; T256-H259 PolarHBondContact O-N 3.02Å; T256-H259 VanDerWaalsContact O-N 3.1Å; T256-H259 PolarHBondContact OG1-ND1 3.33Å; T256-V260 PolarHBondContact O-N 3.18Å; T256-A283 HydrophobicContact CG2-CB 4.17Å
257A93.1Very high91.4Very high0 Ų038.9 Ų38.90%019%0.187CC..Hα-helixtrans-56.3-28.8174.100000112.8L225 L226 A229 A261 L273L225-A257 HydrophobicContact CD2-CB 4.49Å; L225-A257 HydrophobicContact CG-CB 4.33Å; L226-A257 HydrophobicContact CD2-CB 3.97Å; A229-A257 HydrophobicContact CB-CB 4.22Å; A257-A261 VanDerWaalsContact O-CB 3.31Å; A257-A261 WeakPolarHBondContact O-CB 3.4Å; A257-A261 PolarHBondContact O-N 3.46Å; A257-L273 HydrophobicContact CB-CD1 3.92Å; A257-L273 HydrophobicContact CB-CD2 4.24Å
258L93.7Very high91.7Very high0 Ų045.2 Ų45.20%022%0.217CC..Hα-helixtrans-70-38.2178.3-168.261.1000112.4T256 A262 V270 L273 I274 V279 P281 P291 L307T256-L258 PolarHBondContact O-N 3.17Å; T256-L258 VanDerWaalsContact O-N 3.13Å; T256-L258 PolarHBondContact OG1-N 3.01Å; L258-A262 WeakPolarHBondContact O-CB 3.49Å; L258-A262 PolarHBondContact O-N 2.93Å; L258-V270 HydrophobicContact CD1-CG1 4.18Å; L258-V270 HydrophobicContact CD1-CG2 4.49Å; L258-L273 HydrophobicContact CB-CD1 4.39Å; L258-L273 HydrophobicContact CD1-CB 4.23Å; L258-L273 HydrophobicContact CD1-CD1 4.24Å; L258-I274 HydrophobicContact CD1-CG1 4.26Å; L258-V279 HydrophobicContact CB-CG1 4.27Å; L258-V279 HydrophobicContact CD2-CG1 4.4Å; L258-P281 HydrophobicContact CD2-CB 4.49Å; L258-P291 HydrophobicContact CB-CG 4.3Å; L258-P291 HydrophobicContact CD2-CB 4.27Å; L258-P291 HydrophobicContact CD2-CG 4.06Å; L258-P291 HydrophobicContact CG-CB 3.95Å; L258-P291 HydrophobicContact CG-CG 4.03Å; L258-L307 HydrophobicContact CD1-CD2 4.2Å; L258-L307 HydrophobicContact CD2-CD2 4.21Å; L258-L307 HydrophobicContact CG-CD2 4.37Å
259H93.1Very high91.9Very high1 Ų141.2 Ų41.21%0.00520%0.198CC..Hα-helixtrans-61.1-49.3174.7-67.782.7000110.7R255 T256 A261 A262 A263 A283 D294R255-H259 HydrophobicContact CB-CB 4Å; R255-H259 HydrophobicContact CG-CB 4.28Å; T256-H259 PolarHBondContact N-ND1 3.24Å; T256-H259 VanDerWaalsContact N-ND1 3.13Å; T256-H259 WeakPolarHBondContact O-CB 3.21Å; T256-H259 PolarHBondContact O-N 3.02Å; T256-H259 VanDerWaalsContact O-N 3.1Å; T256-H259 PolarHBondContact OG1-ND1 3.33Å; H259-A261 PolarHBondContact O-N 3.12Å; H259-A262 PolarHBondContact O-N 3.46Å; H259-A263 WeakPolarHBondContact O-CB 3.42Å; H259-A263 PolarHBondContact O-N 2.94Å; H259-A283 PolarHBondContact CE1-O 3.08Å; H259-A283 PolarHBondContact NE2-O 3.44Å; H259-D294 IonicContact CD2-OD2 3.44Å; H259-D294 PolarHBondContact CD2-OD2 3.48Å; H259-D294 IonicContact CG-OD2 3.94Å
260V93.4Very high92.2Very high16 Ų1638.9 Ų38.910%0.09719%0.187CC..Hα-helixtrans-64.7-43.6-178.5-179.20000111.3L226 A229 T256 A262 A263 E264L226-V260 HydrophobicContact CB-CG2 4.41Å; L226-V260 HydrophobicContact CD1-CG2 4.48Å; L226-V260 HydrophobicContact CD2-CG2 4.05Å; A229-V260 HydrophobicContact CB-CB 4.41Å; A229-V260 HydrophobicContact CB-CG1 4.4Å; T256-V260 PolarHBondContact O-N 3.18Å; V260-A262 VanDerWaalsContact C-N 3.32Å; V260-A262 PolarHBondContact O-N 3.27Å; V260-A263 PolarHBondContact O-N 3.49Å; V260-E264 WeakPolarHBondContact O-CG 3.13Å; V260-E264 PolarHBondContact O-N 2.99Å
261A94.4Very high92.4Very high0 Ų038.3 Ų38.30%019%0.185CC..Hα-helixtrans-65.6-35.5177.300000112.8A229 A257 H259 G265 H266 V269 V270 L273A229-A261 HydrophobicContact CB-CB 4.39Å; A257-A261 VanDerWaalsContact O-CB 3.31Å; A257-A261 WeakPolarHBondContact O-CB 3.4Å; A257-A261 PolarHBondContact O-N 3.46Å; H259-A261 PolarHBondContact O-N 3.12Å; A261-G265 PolarHBondContact O-N 3.4Å; A261-G265 VanDerWaalsContact O-N 3.08Å; A261-H266 PolarHBondContact O-N 3.13Å; A261-H266 VanDerWaalsContact O-N 3.11Å; A261-V269 HydrophobicContact CB-CB 4.15Å; A261-V269 HydrophobicContact CB-CG1 3.48Å; A261-V269 VanDerWaalsContact CB-CG1 3.48Å; A261-V270 HydrophobicContact CB-CG2 3.84Å; A261-L273 HydrophobicContact CB-CD1 4.32Å
262A93.9Very high92.6Very high0 Ų038 Ų380%018%0.182CC..Hα-helixtrans-71.6-39.1178.500000112.5L258 H259 V260 G265 P291 A295 V303 L307L258-A262 WeakPolarHBondContact O-CB 3.49Å; L258-A262 PolarHBondContact O-N 2.93Å; H259-A262 PolarHBondContact O-N 3.46Å; V260-A262 VanDerWaalsContact C-N 3.32Å; V260-A262 PolarHBondContact O-N 3.27Å; A262-G265 PolarHBondContact O-N 3.1Å; A262-P291 HydrophobicContact CB-CB 4.18Å; A262-P291 VanDerWaalsContact CB-O 3.28Å; A262-P291 WeakPolarHBondContact CB-O 3.45Å; A262-A295 HydrophobicContact CB-CB 4.24Å; A262-V303 HydrophobicContact CB-CG1 4.23Å; A262-L307 HydrophobicContact CB-CD1 4.05Å
263A93.5Very high92.8Very high18 Ų1830 Ų3015%0.14915%0.151CC..Hα-helixtrans-66.1-37.2176.300000113.2H259 V260 D294 F298 H300H259-A263 WeakPolarHBondContact O-CB 3.42Å; H259-A263 PolarHBondContact O-N 2.94Å; V260-A263 PolarHBondContact O-N 3.49Å; A263-D294 HydrophobicContact CB-CB 4.34Å; A263-F298 HydrophobicContact CB-CD2 3.75Å; A263-F298 HydrophobicContact CB-CE2 3.76Å; A263-F298 WeakPolarHBondContact O-CB 3.36Å; A263-H300 PolarHBondContact O-CD2 3.35Å; A263-H300 PolarHBondContact O-NE2 3.34Å; A263-H300 VanDerWaalsContact O-NE2 3.12Å
264E93.9Very high92.9Very high85 Ų8530.2 Ų30.240%0.39715%0.152SC..Hα-helixtrans-84.6-16.6177.9-65.4-62.4143.100113.6Y230 V260Y230-E264 HydrophobicContact CD2-CG 3.7Å; Y230-E264 WeakPolarHBondContact CD2-OE1 3.49Å; Y230-E264 VanDerWaalsContact CE2-CD 3.47Å; Y230-E264 HydrophobicContact CE2-CG 4.2Å; Y230-E264 WeakPolarHBondContact CE2-OE1 3.31Å; V260-E264 WeakPolarHBondContact O-CG 3.13Å; V260-E264 PolarHBondContact O-N 2.99Å
265G93.3Very high92.8Very high17 Ų1734.7 Ų34.718%0.17517%0.168CC..THydrogen-bonded Turntrans82.621.317900000115.3A261 A262 I267A261-G265 PolarHBondContact O-N 3.4Å; A261-G265 VanDerWaalsContact O-N 3.08Å; A262-G265 PolarHBondContact O-N 3.1Å; G265-I267 PolarHBondContact O-N 3.32Å
266H94.6Very high92.6Very high59 Ų5934.6 Ų34.627%0.27318%0.182SC..  trans-78.591.1-177.7-68.8-51.7000112.6A229 Y230 A261 E268 V269 V270A229-H266 PolarHBondContact O-CD2 3.04Å; A229-H266 VanDerWaalsContact O-CD2 3.26Å; Y230-H266 PolarHBondContact O-CD2 3.09Å; Y230-H266 PolarHBondContact O-NE2 3.19Å; A261-H266 PolarHBondContact O-N 3.13Å; A261-H266 VanDerWaalsContact O-N 3.11Å; H266-E268 PolarHBondContact O-N 3.13Å; H266-V269 HydrophobicContact CB-CB 4Å; H266-V269 HydrophobicContact CB-CG2 4Å; H266-V269 PolarHBondContact O-N 3.06Å; H266-V270 WeakPolarHBondContact O-CG2 3.39Å; H266-V270 PolarHBondContact O-N 3.11Å
267I92.9Very high92.1Very high50 Ų5036.1 Ų36.126%0.25619%0.192SC..Hα-helixtrans-56.6-44.5-174.9-60.9161.9000112.9G265 V269 V270 K271 E302 V303 L306G265-I267 PolarHBondContact O-N 3.32Å; I267-V269 VanDerWaalsContact C-N 3.31Å; I267-V269 PolarHBondContact O-N 3.3Å; I267-V270 PolarHBondContact O-N 2.93Å; I267-K271 HydrophobicContact CG2-CD 4.15Å; I267-K271 HydrophobicContact CG2-CG 4.43Å; I267-K271 WeakPolarHBondContact O-CG 3.42Å; I267-K271 PolarHBondContact O-N 3.33Å; I267-E302 HydrophobicContact CD1-CB 4.12Å; I267-E302 WeakPolarHBondContact CD1-OE2 3.44Å; I267-V303 HydrophobicContact CG1-CG2 3.98Å; I267-L306 HydrophobicContact CG2-CD1 3.71Å
268E93.3Very high91.8Very high144 Ų14443.4 Ų43.467%0.67322%0.224SC*.Hα-helixtrans-66.1-35.6-177.4-59.5-166.8156.800112.2V234 H266 F272V234-E268 HydrophobicContact CG2-CB 3.72Å; H266-E268 PolarHBondContact O-N 3.13Å; E268-F272 WeakPolarHBondContact O-CB 3.31Å; E268-F272 PolarHBondContact O-N 3.02Å
269V94Very high91.5Very high1 Ų143.5 Ų43.51%0.00623%0.225CC..Hα-helixtrans-68.4-46.1175.5172.10000110.4A229 V234 L237 A261 H266 I267 K271 F272 L273A229-V269 HydrophobicContact CB-CG1 4.29Å; V234-V269 HydrophobicContact CG2-CG2 3.78Å; L237-V269 HydrophobicContact CD1-CB 4.14Å; L237-V269 HydrophobicContact CD1-CG1 3.33Å; L237-V269 HydrophobicContact CD1-CG2 3.91Å; A261-V269 HydrophobicContact CB-CB 4.15Å; A261-V269 HydrophobicContact CB-CG1 3.48Å; A261-V269 VanDerWaalsContact CB-CG1 3.48Å; H266-V269 HydrophobicContact CB-CB 4Å; H266-V269 HydrophobicContact CB-CG2 4Å; H266-V269 PolarHBondContact O-N 3.06Å; I267-V269 VanDerWaalsContact C-N 3.31Å; I267-V269 PolarHBondContact O-N 3.3Å; V269-K271 PolarHBondContact O-N 3.26Å; V269-F272 WeakPolarHBondContact O-CB 3.29Å; V269-F272 PolarHBondContact O-N 3.49Å; V269-L273 HydrophobicContact CG1-CD1 3.81Å; V269-L273 HydrophobicContact CG1-CG 4.28Å; V269-L273 WeakPolarHBondContact O-CG 3.38Å; V269-L273 PolarHBondContact O-N 2.96Å
270V93.1Very high91.3Very high0 Ų045.7 Ų45.70%024%0.236CC..Hα-helixtrans-60.4-47.1178.5173.30000110.7L258 A261 H266 I267 F272 L273 I274 V303 L307L258-V270 HydrophobicContact CD1-CG1 4.18Å; L258-V270 HydrophobicContact CD1-CG2 4.49Å; A261-V270 HydrophobicContact CB-CG2 3.84Å; H266-V270 WeakPolarHBondContact O-CG2 3.39Å; H266-V270 PolarHBondContact O-N 3.11Å; I267-V270 PolarHBondContact O-N 2.93Å; V270-F272 VanDerWaalsContact C-N 3.32Å; V270-F272 PolarHBondContact O-N 3.04Å; V270-L273 PolarHBondContact O-N 3.27Å; V270-I274 HydrophobicContact CG1-CD1 3.49Å; V270-I274 VanDerWaalsContact CG1-CD1 3.49Å; V270-I274 HydrophobicContact CG1-CG1 4.32Å; V270-I274 WeakPolarHBondContact O-CB 3.29Å; V270-I274 VanDerWaalsContact O-CG1 3.29Å; V270-I274 WeakPolarHBondContact O-CG1 3.01Å; V270-I274 PolarHBondContact O-N 3.49Å; V270-V303 HydrophobicContact CG1-CG1 4.32Å; V270-V303 HydrophobicContact CG2-CG1 4.02Å; V270-L307 HydrophobicContact CG1-CD2 4.31Å; V270-L307 HydrophobicContact CG1-CG 4.43Å
271K93Very high91Very high91 Ų9144.9 Ų44.940%0.39623%0.232SC..Hα-helixtrans-57.6-44.6174.6-74.2-179.9179.91790112I267 V269 I274 E275 L306I267-K271 HydrophobicContact CG2-CD 4.15Å; I267-K271 HydrophobicContact CG2-CG 4.43Å; I267-K271 WeakPolarHBondContact O-CG 3.42Å; I267-K271 PolarHBondContact O-N 3.33Å; V269-K271 PolarHBondContact O-N 3.26Å; K271-I274 PolarHBondContact O-N 3.39Å; K271-E275 VanDerWaalsContact O-CB 3.29Å; K271-E275 WeakPolarHBondContact O-CB 3.35Å; K271-E275 WeakPolarHBondContact O-CG 3.24Å; K271-E275 PolarHBondContact O-N 2.91Å; K271-L306 HydrophobicContact CG-CD1 4.13Å
272F93.1Very high90.7Very high17 Ų1748.5 Ų48.58%0.07525%0.247CC..Iπ-helixtrans-61.6-46.1177.8177.3-103.1000112.4V234 L237 R238 A241 M247 E268 V269 V270 I274 A276 C277V234-F272 HydrophobicContact CG1-CB 4.34Å; V234-F272 HydrophobicContact CG1-CG 4.37Å; L237-F272 HydrophobicContact CB-CD1 3.92Å; L237-F272 HydrophobicContact CB-CE1 3.77Å; R238-F272 HydrophobicContact CB-CE2 4.46Å; R238-F272 HydrophobicContact CB-CZ 4.32Å; R238-F272 HydrophobicContact CG-CD2 4.03Å; R238-F272 HydrophobicContact CG-CE2 3.48Å; R238-F272 VanDerWaalsContact CG-CE2 3.48Å; R238-F272 HydrophobicContact CG-CZ 3.76Å; A241-F272 HydrophobicContact CB-CE1 4.23Å; A241-F272 HydrophobicContact CB-CZ 3.77Å; M247-F272 HydrophobicContact CE-CE1 4.33Å; E268-F272 WeakPolarHBondContact O-CB 3.31Å; E268-F272 PolarHBondContact O-N 3.02Å; V269-F272 WeakPolarHBondContact O-CB 3.29Å; V269-F272 PolarHBondContact O-N 3.49Å; V270-F272 VanDerWaalsContact C-N 3.32Å; V270-F272 PolarHBondContact O-N 3.04Å; F272-I274 PolarHBondContact O-N 3.33Å; F272-A276 HydrophobicContact CD2-CB 3.87Å; F272-A276 HydrophobicContact CE2-CB 3.77Å; F272-A276 HydrophobicContact CZ-CB 4.47Å; F272-A276 VanDerWaalsContact O-CB 3.24Å; F272-A276 WeakPolarHBondContact O-CB 3.34Å; F272-A276 PolarHBondContact O-N 3.39Å; F272-C277 PolarHBondContact O-N 3.2Å
273L90.8Very high90.4Very high0 Ų049 Ų490%025%0.252CS..Iπ-helixtrans-66.8-37-179.1-69.1172.2000112.6M247 A257 L258 A261 V269 V270 C277 K278 V279M247-L273 HydrophobicContact CE-CD2 3.53Å; A257-L273 HydrophobicContact CB-CD1 3.92Å; A257-L273 HydrophobicContact CB-CD2 4.24Å; L258-L273 HydrophobicContact CB-CD1 4.39Å; L258-L273 HydrophobicContact CD1-CB 4.23Å; L258-L273 HydrophobicContact CD1-CD1 4.24Å; A261-L273 HydrophobicContact CB-CD1 4.32Å; V269-L273 HydrophobicContact CG1-CD1 3.81Å; V269-L273 HydrophobicContact CG1-CG 4.28Å; V269-L273 WeakPolarHBondContact O-CG 3.38Å; V269-L273 PolarHBondContact O-N 2.96Å; V270-L273 PolarHBondContact O-N 3.27Å; L273-C277 CarbonylContact O-C 3.57Å; L273-C277 WeakPolarHBondContact O-CB 3.43Å; L273-C277 PolarHBondContact O-N 3.04Å; L273-K278 PolarHBondContact O-N 3.46Å; L273-V279 HydrophobicContact CB-CG2 4.37Å; L273-V279 HydrophobicContact CD2-CG2 4.34Å; L273-V279 PolarHBondContact O-N 2.88Å
274I90.3Very high90.3Very high14 Ų1454.5 Ų54.57%0.07227%0.272CS..Iπ-helixtrans-75.4-55.4-179.8-72.9175.3000111.5L258 V270 K271 F272 K278 L307 Y310L258-I274 HydrophobicContact CD1-CG1 4.26Å; V270-I274 HydrophobicContact CG1-CD1 3.49Å; V270-I274 VanDerWaalsContact CG1-CD1 3.49Å; V270-I274 HydrophobicContact CG1-CG1 4.32Å; V270-I274 WeakPolarHBondContact O-CB 3.29Å; V270-I274 VanDerWaalsContact O-CG1 3.29Å; V270-I274 WeakPolarHBondContact O-CG1 3.01Å; V270-I274 PolarHBondContact O-N 3.49Å; K271-I274 PolarHBondContact O-N 3.39Å; F272-I274 PolarHBondContact O-N 3.33Å; I274-K278 WeakPolarHBondContact O-CA 3.29Å; I274-K278 PolarHBondContact O-N 2.85Å; I274-L307 HydrophobicContact CD1-CD2 3.76Å; I274-Y310 HydrophobicContact CB-CD1 4.23Å; I274-Y310 HydrophobicContact CB-CE1 4.3Å; I274-Y310 HydrophobicContact CB-CG 4.33Å; I274-Y310 HydrophobicContact CD1-CD1 3.98Å; I274-Y310 HydrophobicContact CD1-CG 4.16Å; I274-Y310 HydrophobicContact CG1-CD1 3.74Å; I274-Y310 HydrophobicContact CG1-CE1 4Å; I274-Y310 HydrophobicContact CG1-CG 4.18Å; I274-Y310 HydrophobicContact CG2-CD1 3.66Å; I274-Y310 HydrophobicContact CG2-CD2 3.24Å; I274-Y310 HydrophobicContact CG2-CE1 3.89Å; I274-Y310 HydrophobicContact CG2-CE2 3.51Å; I274-Y310 HydrophobicContact CG2-CG 3.31Å
275E88.1Confident90.2Very high142 Ų14251 Ų5166%0.66426%0.256SS*.Iπ-helixtrans-78-43.6-171.2-64.2176.2-178.800111.9K271K271-E275 VanDerWaalsContact O-CB 3.29Å; K271-E275 WeakPolarHBondContact O-CB 3.35Å; K271-E275 WeakPolarHBondContact O-CG 3.24Å; K271-E275 PolarHBondContact O-N 2.91Å
276A86.2Confident90.1Very high69 Ų6957.2 Ų57.257%0.5727%0.274SS*.Iπ-helixtrans-92.5-39-17300000113F272F272-A276 HydrophobicContact CD2-CB 3.87Å; F272-A276 HydrophobicContact CE2-CB 3.77Å; F272-A276 HydrophobicContact CZ-CB 4.47Å; F272-A276 VanDerWaalsContact O-CB 3.24Å; F272-A276 WeakPolarHBondContact O-CB 3.34Å; F272-A276 PolarHBondContact O-N 3.39Å
277C82.9Confident89.9Confident34 Ų3462 Ų6223%0.2329%0.29CS..THydrogen-bonded Turntrans-98.4-15.5-176.4-60.90000114.1M247 F272 L273 V279M247-C277 HydrophobicContact CB-CB 4.27Å; M247-C277 HydrophobicContact CG-CB 4.15Å; F272-C277 PolarHBondContact O-N 3.2Å; L273-C277 CarbonylContact O-C 3.57Å; L273-C277 WeakPolarHBondContact O-CB 3.43Å; L273-C277 PolarHBondContact O-N 3.04Å; C277-V279 VanDerWaalsContact C-N 3.29Å; C277-V279 HydrophobicContact CB-CG2 3.91Å; C277-V279 PolarHBondContact O-N 3.41Å
278K86.5Confident89.6Confident154 Ų15461.5 Ų61.567%0.6730%0.297SS*.  trans50.245.4-178.3-60.7-174176.2-172.90113.6L273 I274 Y310L273-K278 PolarHBondContact O-N 3.46Å; I274-K278 WeakPolarHBondContact O-CA 3.29Å; I274-K278 PolarHBondContact O-N 2.85Å; K278-Y310 WeakPolarHBondContact CA-OH 3.39Å
279V87.8Confident89.5Confident2 Ų256.8 Ų56.81%0.01228%0.277CS..  trans-68.9137.7179.6176.50000110.5M247 E248 L258 L273 C277 P281M247-V279 HydrophobicContact CB-CG2 4Å; E248-V279 HydrophobicContact CG-CG1 4.31Å; L258-V279 HydrophobicContact CB-CG1 4.27Å; L258-V279 HydrophobicContact CD2-CG1 4.4Å; L273-V279 HydrophobicContact CB-CG2 4.37Å; L273-V279 HydrophobicContact CD2-CG2 4.34Å; L273-V279 PolarHBondContact O-N 2.88Å; C277-V279 VanDerWaalsContact C-N 3.29Å; C277-V279 HydrophobicContact CB-CG2 3.91Å; C277-V279 PolarHBondContact O-N 3.41Å; V279-P281 WeakPolarHBondContact O-CD 3.36Å
280N87.8Confident89.5Confident46 Ų4658 Ų5825%0.24628%0.283CS..  trans-58.4119.6178.7-175.3-9.1000112.9E248 F282E248-N280 WeakPolarHBondContact OE1-CB 3.42Å; E248-N280 PolarHBondContact OE1-N 3.06Å; N280-F282 VanDerWaalsContact C-N 3.32Å; N280-F282 PolarHBondContact O-N 3.22Å; N280-F282 PolarHBondContact OD1-N 2.83Å
281P88Confident89.4Confident0 Ų058 Ų580%028%0.283CS..THydrogen-bonded Turntrans-80.2-8-179.533.2-34.7000114.2L258 V279 P291 Y310 Q311 Y314L258-P281 HydrophobicContact CD2-CB 4.49Å; V279-P281 WeakPolarHBondContact O-CD 3.36Å; P281-P291 WeakPolarHBondContact O-CD 3.44Å; P281-Y310 HydrophobicContact CB-CD1 3.86Å; P281-Y310 HydrophobicContact CB-CE1 4.09Å; P281-Y310 HydrophobicContact CG-CD1 3.84Å; P281-Y310 HydrophobicContact CG-CE1 3.83Å; P281-Q311 HydrophobicContact CB-CG 4.01Å; P281-Q311 HydrophobicContact CG-CG 4.15Å; P281-Y314 HydrophobicContact CG-CD1 4.43Å; P281-Y314 HydrophobicContact CG-CD2 4.22Å; P281-Y314 HydrophobicContact CG-CG 4.01Å
282F87.6Confident89.4Confident75 Ų7554.6 Ų54.633%0.32927%0.269SS..THydrogen-bonded Turntrans-1039.7179.4-59.7-73000113.3N280 K284 Q311 Y314 T315N280-F282 VanDerWaalsContact C-N 3.32Å; N280-F282 PolarHBondContact O-N 3.22Å; N280-F282 PolarHBondContact OD1-N 2.83Å; F282-K284 PolarHBondContact O-N 3.08Å; F282-Q311 HydrophobicContact CE1-CB 4.34Å; F282-Q311 HydrophobicContact CE1-CG 3.87Å; F282-Q311 HydrophobicContact CE2-CG 4.4Å; F282-Q311 HydrophobicContact CZ-CB 3.85Å; F282-Q311 HydrophobicContact CZ-CG 3.72Å; F282-Y314 HydrophobicContact CD2-CD1 4.13Å; F282-Y314 HydrophobicContact CD2-CE1 4.45Å; F282-Y314 AromaticContact CE2-CD1 3.91Å; F282-Y314 HydrophobicContact CE2-CD1 3.91Å; F282-T315 HydrophobicContact CE2-CG2 3.91Å; F282-T315 HydrophobicContact CZ-CG2 3.74Å
283A88Confident89.4Confident11 Ų1157.1 Ų57.19%0.09128%0.283CS..  trans-58.6127.8173.300000109.4T256 H259 P291T256-A283 HydrophobicContact CG2-CB 4.17Å; H259-A283 PolarHBondContact CE1-O 3.08Å; H259-A283 PolarHBondContact NE2-O 3.44Å; A283-P291 WeakPolarHBondContact O-CD 3.48Å
284K91.5Very high89.4Confident134 Ų13457.7 Ų57.758%0.58329%0.286SS*.  trans-95.2139.9176.8-63.3-178.8-179.7-178.30111F282 N289 I290F282-K284 PolarHBondContact O-N 3.08Å; K284-N289 WeakPolarHBondContact CA-O 3.28Å; K284-I290 HydrophobicContact CG-CG2 4.13Å
285D91.4Very high89.5Confident12 Ų1257 Ų576%0.06428%0.283CS..  trans-81.7-173.8169.474.32.9000112.2R255 W287 G288 N289R255-D285 HydrophobicContact CG-CB 3.77Å; D285-W287 VanDerWaalsContact C-N 3.26Å; D285-W287 PolarHBondContact O-N 3.06Å; D285-W287 WeakPolarHBondContact OD1-CA 3.46Å; D285-W287 PolarHBondContact OD1-N 2.9Å; D285-G288 PolarHBondContact O-N 3.33Å; D285-G288 PolarHBondContact OD1-N 3.2Å; D285-N289 PolarHBondContact N-O 3.33Å; D285-N289 PolarHBondContact OD1-N 3.2Å
286R91.6Very high89.8Confident146 Ų14654.3 Ų54.355%0.55128%0.276SS*.THydrogen-bonded Turntrans-62.9-29.2176.3-179.9-175.6-73.6167.1-1113.4Y252 D253 G288Y252-R286 PolarHBondContact O-NH2 2.89Å; D253-R286 WeakPolarHBondContact O-CB 3.35Å; D253-R286 PolarHBondContact O-N 3.44Å; D253-R286 IonicContact OD1-CZ 3.38Å; D253-R286 IonicContact OD1-NE 3.25Å; D253-R286 IonicContact OD1-NH1 2.74Å; D253-R286 PolarHBondContact OD1-NH1 2.82Å; D253-R286 IonicContact OD1-NH2 3.95Å; D253-R286 PolarHBondContact OD1-NH2 3.42Å; R286-G288 VanDerWaalsContact C-N 3.33Å
287W89.4Confident90Very high159 Ų15957.2 Ų57.260%0.60228%0.278SS*.THydrogen-bonded Turntrans-88.6-5-178.6-62.9-80.3000112.7D253 D285 N289D253-W287 HydrophobicContact CB-CH2 4.08Å; D253-W287 HydrophobicContact CB-CZ3 3.91Å; D285-W287 VanDerWaalsContact C-N 3.26Å; D285-W287 PolarHBondContact O-N 3.06Å; D285-W287 WeakPolarHBondContact OD1-CA 3.46Å; D285-W287 PolarHBondContact OD1-N 2.9Å; W287-N289 VanDerWaalsContact C-N 3.33Å
288G88.4Confident90.4Very high40 Ų4060.9 Ų60.941%0.41229%0.29SS..SBendtrans85.95.7-179.200000113.7D285 R286D285-G288 PolarHBondContact O-N 3.33Å; D285-G288 PolarHBondContact OD1-N 3.2Å; R286-G288 VanDerWaalsContact C-N 3.33Å
289N91.1Very high90.7Very high45 Ų4559.3 Ų59.324%0.24129%0.289CS..  trans-77.5147.2177.1-64.2-12.7000110.1K284 D285 W287 D293K284-N289 WeakPolarHBondContact CA-O 3.28Å; D285-N289 PolarHBondContact N-O 3.33Å; D285-N289 PolarHBondContact OD1-N 3.2Å; W287-N289 VanDerWaalsContact C-N 3.33Å; N289-D293 HydrophobicContact CB-CB 4.14Å
290I92.4Very high91Very high27 Ų2762.1 Ų62.114%0.13830%0.302CS..  trans-98.8162.4167.453.1164.3000110.2K284 L292 D293 D294K284-I290 HydrophobicContact CG-CG2 4.13Å; I290-L292 HydrophobicContact CD1-CB 3.85Å; I290-L292 HydrophobicContact CD1-CD2 4.48Å; I290-L292 HydrophobicContact CG1-CB 4.2Å; I290-L292 PolarHBondContact O-N 2.99Å; I290-D293 HydrophobicContact CG1-CB 4.26Å; I290-D293 VanDerWaalsContact CG1-CG 3.48Å; I290-D293 WeakPolarHBondContact CG1-OD2 3.46Å; I290-D293 PolarHBondContact N-OD2 3Å; I290-D293 WeakPolarHBondContact O-CA 3.46Å; I290-D293 WeakPolarHBondContact O-CB 3.45Å; I290-D293 PolarHBondContact O-N 3.11Å; I290-D294 PolarHBondContact O-N 2.86Å
291P92.4Very high91.1Very high0 Ų065.4 Ų65.40%032%0.319CS..Hα-helixtrans-53.6-29.3178.4-2733.7000114.2L258 A262 P281 A283 A295 L307L258-P291 HydrophobicContact CB-CG 4.3Å; L258-P291 HydrophobicContact CD2-CB 4.27Å; L258-P291 HydrophobicContact CD2-CG 4.06Å; L258-P291 HydrophobicContact CG-CB 3.95Å; L258-P291 HydrophobicContact CG-CG 4.03Å; A262-P291 HydrophobicContact CB-CB 4.18Å; A262-P291 VanDerWaalsContact CB-O 3.28Å; A262-P291 WeakPolarHBondContact CB-O 3.45Å; P281-P291 WeakPolarHBondContact O-CD 3.44Å; A283-P291 WeakPolarHBondContact O-CD 3.48Å; P291-A295 PolarHBondContact O-N 3.11Å; P291-A295 VanDerWaalsContact O-N 3.11Å; P291-L307 HydrophobicContact CB-CD1 4.38Å
292L93.1Very high91.2Very high20 Ų2071.5 Ų71.511%0.10535%0.347CS..Hα-helixtrans-66.5-41.6174.3-178.666.2000112.1I290 D294 A295 V296 V304 L307 Q308I290-L292 HydrophobicContact CD1-CB 3.85Å; I290-L292 HydrophobicContact CD1-CD2 4.48Å; I290-L292 HydrophobicContact CG1-CB 4.2Å; I290-L292 PolarHBondContact O-N 2.99Å; L292-D294 VanDerWaalsContact C-N 3.32Å; L292-A295 PolarHBondContact O-N 3.3Å; L292-V296 WeakPolarHBondContact O-CG2 3.45Å; L292-V296 PolarHBondContact O-N 3.08Å; L292-V304 HydrophobicContact CD1-CB 4.3Å; L292-V304 HydrophobicContact CD1-CG1 3.94Å; L292-V304 HydrophobicContact CD1-CG2 4.43Å; L292-L307 HydrophobicContact CD1-CB 3.88Å; L292-Q308 HydrophobicContact CD1-CG 3.98Å; L292-Q308 HydrophobicContact CD2-CG 4.13Å
293D92.5Very high91.5Very high69 Ų6968 Ų6837%0.36933%0.332SS..Hα-helixtrans-65.2-40.3178.9-62.5-29.1000110.4N289 I290 V296 Q297N289-D293 HydrophobicContact CB-CB 4.14Å; I290-D293 HydrophobicContact CG1-CB 4.26Å; I290-D293 VanDerWaalsContact CG1-CG 3.48Å; I290-D293 WeakPolarHBondContact CG1-OD2 3.46Å; I290-D293 PolarHBondContact N-OD2 3Å; I290-D293 WeakPolarHBondContact O-CA 3.46Å; I290-D293 WeakPolarHBondContact O-CB 3.45Å; I290-D293 PolarHBondContact O-N 3.11Å; D293-V296 PolarHBondContact O-N 3.29Å; D293-Q297 WeakPolarHBondContact O-CB 3.41Å; D293-Q297 PolarHBondContact O-N 3.26Å
294D90.6Very high91.7Very high12 Ų1268.3 Ų68.36%0.06433%0.332CS..Hα-helixtrans-60.1-47.4174.2-70-17.4000110.8H259 A263 I290 L292 V296 Q297 F298H259-D294 IonicContact CD2-OD2 3.44Å; H259-D294 PolarHBondContact CD2-OD2 3.48Å; H259-D294 IonicContact CG-OD2 3.94Å; A263-D294 HydrophobicContact CB-CB 4.34Å; I290-D294 PolarHBondContact O-N 2.86Å; L292-D294 VanDerWaalsContact C-N 3.32Å; D294-V296 VanDerWaalsContact C-N 3.29Å; D294-V296 PolarHBondContact O-N 3.13Å; D294-Q297 PolarHBondContact O-N 2.91Å; D294-F298 WeakPolarHBondContact O-CD2 3.16Å; D294-F298 PolarHBondContact O-N 3.08Å
295A93.2Very high91.7Very high0 Ų068.3 Ų68.30%033%0.333CS..Hα-helixtrans-61.2-36.117700000113A262 P291 L292 N299 H300 V303 V304 L307A262-A295 HydrophobicContact CB-CB 4.24Å; P291-A295 PolarHBondContact O-N 3.11Å; P291-A295 VanDerWaalsContact O-N 3.11Å; L292-A295 PolarHBondContact O-N 3.3Å; A295-N299 PolarHBondContact O-N 2.91Å; A295-H300 PolarHBondContact O-N 3.47Å; A295-V303 HydrophobicContact CB-CB 4.4Å; A295-V303 HydrophobicContact CB-CG1 4Å; A295-V304 HydrophobicContact CB-CG2 3.74Å; A295-L307 HydrophobicContact CB-CD1 4.22Å
296V93.1Very high91.7Very high85 Ų8570 Ų7052%0.51534%0.342SS..Hα-helixtrans-70.3-43.4175.6172.50000110.9L292 D293 D294 F298 N299 V304L292-V296 WeakPolarHBondContact O-CG2 3.45Å; L292-V296 PolarHBondContact O-N 3.08Å; D293-V296 PolarHBondContact O-N 3.29Å; D294-V296 VanDerWaalsContact C-N 3.29Å; D294-V296 PolarHBondContact O-N 3.13Å; V296-F298 VanDerWaalsContact C-N 3.32Å; V296-F298 PolarHBondContact O-N 3.46Å; V296-N299 PolarHBondContact O-N 3.43Å; V296-N299 VanDerWaalsContact O-N 3.08Å; V296-V304 HydrophobicContact CG2-CG1 4.26Å; V296-V304 HydrophobicContact CG2-CG2 3.72Å
297Q91.9Very high91.6Very high130 Ų13063.1 Ų63.161%0.60732%0.316SS*.Hα-helixtrans-61.2-40.3-179.3-178.1176.3-10.200112.1D293 D294 N299D293-Q297 WeakPolarHBondContact O-CB 3.41Å; D293-Q297 PolarHBondContact O-N 3.26Å; D294-Q297 PolarHBondContact O-N 2.91Å; Q297-N299 VanDerWaalsContact C-N 3.33Å
298F91.3Very high91.6Very high112 Ų11259.8 Ų59.849%0.49131%0.306SS..THydrogen-bonded Turntrans-893.9177.1-65-73.6000113.7A263 D294 V296A263-F298 HydrophobicContact CB-CD2 3.75Å; A263-F298 HydrophobicContact CB-CE2 3.76Å; A263-F298 WeakPolarHBondContact O-CB 3.36Å; D294-F298 WeakPolarHBondContact O-CD2 3.16Å; D294-F298 PolarHBondContact O-N 3.08Å; V296-F298 VanDerWaalsContact C-N 3.32Å; V296-F298 PolarHBondContact O-N 3.46Å
299N92.6Very high91.6Very high120 Ų12062.9 Ų62.964%0.64231%0.314SS*.THydrogen-bonded Turntrans6339.1174.7-161.425.4000115.1A295 V296 Q297 L301A295-N299 PolarHBondContact O-N 2.91Å; V296-N299 PolarHBondContact O-N 3.43Å; V296-N299 VanDerWaalsContact O-N 3.08Å; Q297-N299 VanDerWaalsContact C-N 3.33Å; N299-L301 PolarHBondContact O-N 3.31Å
300H93.3Very high91.5Very high61 Ų6162.1 Ų62.128%0.28231%0.308SS..  trans-92.974.5177.4-65-56.3000112.4A263 A295 E302 V303 V304A263-H300 PolarHBondContact O-CD2 3.35Å; A263-H300 PolarHBondContact O-NE2 3.34Å; A263-H300 VanDerWaalsContact O-NE2 3.12Å; A295-H300 PolarHBondContact O-N 3.47Å; H300-E302 VanDerWaalsContact C-N 3.26Å; H300-E302 PolarHBondContact O-N 3.31Å; H300-E302 VanDerWaalsContact O-N 3.11Å; H300-V303 HydrophobicContact CB-CB 4.25Å; H300-V303 HydrophobicContact CB-CG2 4.41Å; H300-V303 PolarHBondContact O-N 3.24Å; H300-V303 VanDerWaalsContact O-N 3.08Å; H300-V304 WeakPolarHBondContact O-CG2 3.44Å; H300-V304 PolarHBondContact O-N 3.37Å; H300-V304 VanDerWaalsContact O-N 3.08Å
301L90.5Very high91.1Very high115 Ų11562 Ų6260%0.60231%0.307SS*.Hα-helixtrans-54.3-32.9-173.2-61.2175.4000115.3N299 K305N299-L301 PolarHBondContact O-N 3.31Å; L301-K305 WeakPolarHBondContact O-CG 3.4Å; L301-K305 PolarHBondContact O-N 2.79Å
302E90.6Very high90.6Very high129 Ų12967 Ų6760%0.60333%0.333SS*.Hα-helixtrans-73-38.2179.7-64.2-171.6178.100112.2I267 H300 L306I267-E302 HydrophobicContact CD1-CB 4.12Å; I267-E302 WeakPolarHBondContact CD1-OE2 3.44Å; H300-E302 VanDerWaalsContact C-N 3.26Å; H300-E302 PolarHBondContact O-N 3.31Å; H300-E302 VanDerWaalsContact O-N 3.11Å; E302-L306 PolarHBondContact O-N 3.17Å
303V92.1Very high90Very high2 Ų268.8 Ų68.81%0.01235%0.347CS..Hα-helixtrans-70.4-37.3175.8175.20000110.7A262 I267 V270 A295 H300 K305 L306 L307A262-V303 HydrophobicContact CB-CG1 4.23Å; I267-V303 HydrophobicContact CG1-CG2 3.98Å; V270-V303 HydrophobicContact CG1-CG1 4.32Å; V270-V303 HydrophobicContact CG2-CG1 4.02Å; A295-V303 HydrophobicContact CB-CB 4.4Å; A295-V303 HydrophobicContact CB-CG1 4Å; H300-V303 HydrophobicContact CB-CB 4.25Å; H300-V303 HydrophobicContact CB-CG2 4.41Å; H300-V303 PolarHBondContact O-N 3.24Å; H300-V303 VanDerWaalsContact O-N 3.08Å; V303-K305 VanDerWaalsContact C-N 3.34Å; V303-K305 PolarHBondContact O-N 2.85Å; V303-L306 PolarHBondContact O-N 3.01Å; V303-L307 HydrophobicContact CG1-CD1 3.73Å; V303-L307 HydrophobicContact CG1-CG 4.2Å; V303-L307 WeakPolarHBondContact O-CB 3.43Å; V303-L307 WeakPolarHBondContact O-CG 3.34Å; V303-L307 PolarHBondContact O-N 3.27Å
304V92.2Very high89.3Confident16 Ų1667.6 Ų67.610%0.09734%0.338CS..Hα-helixtrans-56.4-47.1174.7170.30000111.4L292 A295 V296 H300 L307 Q308L292-V304 HydrophobicContact CD1-CB 4.3Å; L292-V304 HydrophobicContact CD1-CG1 3.94Å; L292-V304 HydrophobicContact CD1-CG2 4.43Å; A295-V304 HydrophobicContact CB-CG2 3.74Å; V296-V304 HydrophobicContact CG2-CG1 4.26Å; V296-V304 HydrophobicContact CG2-CG2 3.72Å; H300-V304 WeakPolarHBondContact O-CG2 3.44Å; H300-V304 PolarHBondContact O-N 3.37Å; H300-V304 VanDerWaalsContact O-N 3.08Å; V304-L307 PolarHBondContact O-N 2.92Å; V304-Q308 HydrophobicContact CG1-CG 4.48Å; V304-Q308 WeakPolarHBondContact O-CB 3.31Å; V304-Q308 VanDerWaalsContact O-CG 3.31Å; V304-Q308 WeakPolarHBondContact O-CG 3.5Å; V304-Q308 PolarHBondContact O-N 3.3Å
305K92.4Very high88.5Confident135 Ų13569.8 Ų69.859%0.58735%0.352SS*.Hα-helixtrans-60.4-48.3177.4-70.6175.2-177.11780111.7L301 V303 L307 Q308 D309L301-K305 WeakPolarHBondContact O-CG 3.4Å; L301-K305 PolarHBondContact O-N 2.79Å; V303-K305 VanDerWaalsContact C-N 3.34Å; V303-K305 PolarHBondContact O-N 2.85Å; K305-L307 VanDerWaalsContact C-N 3.32Å; K305-L307 PolarHBondContact O-N 2.87Å; K305-Q308 PolarHBondContact O-N 3.35Å; K305-D309 VanDerWaalsContact O-CG 3.22Å; K305-D309 PolarHBondContact O-N 2.97Å
306L91.5Very high87.1Confident48 Ų4874.8 Ų74.825%0.25138%0.378SS..Hα-helixtrans-61.4-39.7179.4-71.1170.7000112.6I267 K271 E302 V303 Y310I267-L306 HydrophobicContact CG2-CD1 3.71Å; K271-L306 HydrophobicContact CG-CD1 4.13Å; E302-L306 PolarHBondContact O-N 3.17Å; V303-L306 PolarHBondContact O-N 3.01Å; L306-Y310 WeakPolarHBondContact O-CB 3.31Å; L306-Y310 PolarHBondContact O-N 3.24Å; L306-Y310 VanDerWaalsContact O-N 3.08Å
307L89.1Confident85.7Confident1 Ų173.7 Ų73.71%0.00537%0.374CS..Hα-helixtrans-71.5-38.3177.9-75.1171.3000112.3L258 A262 V270 I274 P291 L292 A295 V303 V304 K305 Y310 Q311L258-L307 HydrophobicContact CD1-CD2 4.2Å; L258-L307 HydrophobicContact CD2-CD2 4.21Å; L258-L307 HydrophobicContact CG-CD2 4.37Å; A262-L307 HydrophobicContact CB-CD1 4.05Å; V270-L307 HydrophobicContact CG1-CD2 4.31Å; V270-L307 HydrophobicContact CG1-CG 4.43Å; I274-L307 HydrophobicContact CD1-CD2 3.76Å; P291-L307 HydrophobicContact CB-CD1 4.38Å; L292-L307 HydrophobicContact CD1-CB 3.88Å; A295-L307 HydrophobicContact CB-CD1 4.22Å; V303-L307 HydrophobicContact CG1-CD1 3.73Å; V303-L307 HydrophobicContact CG1-CG 4.2Å; V303-L307 WeakPolarHBondContact O-CB 3.43Å; V303-L307 WeakPolarHBondContact O-CG 3.34Å; V303-L307 PolarHBondContact O-N 3.27Å; V304-L307 PolarHBondContact O-N 2.92Å; K305-L307 VanDerWaalsContact C-N 3.32Å; K305-L307 PolarHBondContact O-N 2.87Å; L307-Y310 PolarHBondContact O-N 3.14Å; L307-Q311 WeakPolarHBondContact O-CB 3.3Å; L307-Q311 VanDerWaalsContact O-CG 3.31Å; L307-Q311 WeakPolarHBondContact O-CG 3.32Å; L307-Q311 PolarHBondContact O-N 3.4Å
308Q89.3Confident84.3Confident88 Ų8871.6 Ų71.641%0.41136%0.364SS..Hα-helixtrans-62.5-50.2174.4-77.1173-11.100111.2L292 V304 K305 Y310 Q311 D312L292-Q308 HydrophobicContact CD1-CG 3.98Å; L292-Q308 HydrophobicContact CD2-CG 4.13Å; V304-Q308 HydrophobicContact CG1-CG 4.48Å; V304-Q308 WeakPolarHBondContact O-CB 3.31Å; V304-Q308 VanDerWaalsContact O-CG 3.31Å; V304-Q308 WeakPolarHBondContact O-CG 3.5Å; V304-Q308 PolarHBondContact O-N 3.3Å; K305-Q308 PolarHBondContact O-N 3.35Å; Q308-Y310 PolarHBondContact O-N 2.85Å; Q308-Q311 PolarHBondContact O-N 3.44Å; Q308-Q311 VanDerWaalsContact O-N 3.14Å; Q308-D312 PolarHBondContact O-N 3.02Å
309D88.8Confident82.9Confident106 Ų10670 Ų7057%0.56736%0.364SS*.Hα-helixtrans-56.8-39.6176.6-66.9-19.5000110.9K305 S313K305-D309 VanDerWaalsContact O-CG 3.22Å; K305-D309 PolarHBondContact O-N 2.97Å; D309-S313 PolarHBondContact O-N 3.08Å; D309-S313 VanDerWaalsContact O-N 3.14Å
310Y87.9Confident81.3Confident29 Ų2970.9 Ų70.911%0.11436%0.364CS..Hα-helixtrans-71.5-40.7177.7-173.7-125000113.3I274 K278 P281 L306 L307 Q308 D312 S313 Y314I274-Y310 HydrophobicContact CB-CD1 4.23Å; I274-Y310 HydrophobicContact CB-CE1 4.3Å; I274-Y310 HydrophobicContact CB-CG 4.33Å; I274-Y310 HydrophobicContact CD1-CD1 3.98Å; I274-Y310 HydrophobicContact CD1-CG 4.16Å; I274-Y310 HydrophobicContact CG1-CD1 3.74Å; I274-Y310 HydrophobicContact CG1-CE1 4Å; I274-Y310 HydrophobicContact CG1-CG 4.18Å; I274-Y310 HydrophobicContact CG2-CD1 3.66Å; I274-Y310 HydrophobicContact CG2-CD2 3.24Å; I274-Y310 HydrophobicContact CG2-CE1 3.89Å; I274-Y310 HydrophobicContact CG2-CE2 3.51Å; I274-Y310 HydrophobicContact CG2-CG 3.31Å; K278-Y310 WeakPolarHBondContact CA-OH 3.39Å; P281-Y310 HydrophobicContact CB-CD1 3.86Å; P281-Y310 HydrophobicContact CB-CE1 4.09Å; P281-Y310 HydrophobicContact CG-CD1 3.84Å; P281-Y310 HydrophobicContact CG-CE1 3.83Å; L306-Y310 WeakPolarHBondContact O-CB 3.31Å; L306-Y310 PolarHBondContact O-N 3.24Å; L306-Y310 VanDerWaalsContact O-N 3.08Å; L307-Y310 PolarHBondContact O-N 3.14Å; Q308-Y310 PolarHBondContact O-N 2.85Å; Y310-D312 VanDerWaalsContact C-N 3.32Å; Y310-D312 PolarHBondContact O-N 3.14Å; Y310-S313 WeakPolarHBondContact CA-OG 3.42Å; Y310-S313 VanDerWaalsContact CD2-OG 3.32Å; Y310-S313 WeakPolarHBondContact CD2-OG 3.48Å; Y310-S313 CarbonylContact O-C 3.5Å; Y310-S313 PolarHBondContact O-N 2.8Å; Y310-S313 VanDerWaalsContact O-N 3.16Å; Y310-S313 PolarHBondContact O-OG 3.16Å; Y310-Y314 HydrophobicContact CE1-CD2 4.26Å; Y310-Y314 AromaticContact CZ-CD2 3.96Å; Y310-Y314 VanDerWaalsContact O-CB 3.3Å; Y310-Y314 WeakPolarHBondContact O-CB 3.38Å; Y310-Y314 PolarHBondContact O-N 2.73Å
311Q85.8Confident79.7Confident24 Ų2470.9 Ų70.911%0.11237%0.374CS..Hα-helixtrans-60.2-41.6175.8-78.8179.3-10.700112.1P281 F282 L307 Q308 S313 Y314 T315P281-Q311 HydrophobicContact CB-CG 4.01Å; P281-Q311 HydrophobicContact CG-CG 4.15Å; F282-Q311 HydrophobicContact CE1-CB 4.34Å; F282-Q311 HydrophobicContact CE1-CG 3.87Å; F282-Q311 HydrophobicContact CE2-CG 4.4Å; F282-Q311 HydrophobicContact CZ-CB 3.85Å; F282-Q311 HydrophobicContact CZ-CG 3.72Å; L307-Q311 WeakPolarHBondContact O-CB 3.3Å; L307-Q311 VanDerWaalsContact O-CG 3.31Å; L307-Q311 WeakPolarHBondContact O-CG 3.32Å; L307-Q311 PolarHBondContact O-N 3.4Å; Q308-Q311 PolarHBondContact O-N 3.44Å; Q308-Q311 VanDerWaalsContact O-N 3.14Å; Q311-S313 VanDerWaalsContact C-N 3.34Å; Q311-Y314 PolarHBondContact O-N 3Å; Q311-T315 WeakPolarHBondContact O-CG2 3.24Å; Q311-T315 PolarHBondContact O-N 3.02Å; Q311-T315 PolarHBondContact O-OG1 3.49Å
312D82.1Confident78.3Confident105 Ų10571.5 Ų71.556%0.56138%0.375SS*.Hα-helixtrans-63-42.7174.8-70.7-17.7000110.7Q308 Y310 Y314 T315 L316Q308-D312 PolarHBondContact O-N 3.02Å; Y310-D312 VanDerWaalsContact C-N 3.32Å; Y310-D312 PolarHBondContact O-N 3.14Å; D312-Y314 PolarHBondContact O-N 3.48Å; D312-T315 PolarHBondContact O-OG1 2.97Å; D312-T315 VanDerWaalsContact O-OG1 3.05Å; D312-L316 WeakPolarHBondContact O-CD1 3.43Å; D312-L316 VanDerWaalsContact O-CG 3.24Å; D312-L316 WeakPolarHBondContact O-CG 3.47Å; D312-L316 PolarHBondContact O-N 3.05Å
313S79.6Confident76.8Confident57 Ų5768.1 Ų68.140%0.39937%0.369SS..Hα-helixtrans-67.2-34.9176.279.20000113.4D309 Y310 Q311 S317D309-S313 PolarHBondContact O-N 3.08Å; D309-S313 VanDerWaalsContact O-N 3.14Å; Y310-S313 WeakPolarHBondContact CA-OG 3.42Å; Y310-S313 VanDerWaalsContact CD2-OG 3.32Å; Y310-S313 WeakPolarHBondContact CD2-OG 3.48Å; Y310-S313 CarbonylContact O-C 3.5Å; Y310-S313 PolarHBondContact O-N 2.8Å; Y310-S313 VanDerWaalsContact O-N 3.16Å; Y310-S313 PolarHBondContact O-OG 3.16Å; Q311-S313 VanDerWaalsContact C-N 3.34Å; S313-S317 PolarHBondContact O-N 2.94Å
314Y78.2Confident75.3Confident45 Ų4570.6 Ų70.618%0.17639%0.389CS..Hα-helixtrans-73-46-176.5-168.1-83.2000110.8P281 F282 Y310 Q311 D312 L316 S317 E318P281-Y314 HydrophobicContact CG-CD1 4.43Å; P281-Y314 HydrophobicContact CG-CD2 4.22Å; P281-Y314 HydrophobicContact CG-CG 4.01Å; F282-Y314 HydrophobicContact CD2-CD1 4.13Å; F282-Y314 HydrophobicContact CD2-CE1 4.45Å; F282-Y314 AromaticContact CE2-CD1 3.91Å; F282-Y314 HydrophobicContact CE2-CD1 3.91Å; Y310-Y314 HydrophobicContact CE1-CD2 4.26Å; Y310-Y314 AromaticContact CZ-CD2 3.96Å; Y310-Y314 VanDerWaalsContact O-CB 3.3Å; Y310-Y314 WeakPolarHBondContact O-CB 3.38Å; Y310-Y314 PolarHBondContact O-N 2.73Å; Q311-Y314 PolarHBondContact O-N 3Å; D312-Y314 PolarHBondContact O-N 3.48Å; Y314-L316 VanDerWaalsContact C-N 3.31Å; Y314-L316 PolarHBondContact O-N 3.3Å; Y314-S317 PolarHBondContact O-N 3.33Å; Y314-S317 PolarHBondContact O-OG 2.96Å; Y314-E318 PolarHBondContact O-N 2.7Å
315T73.1Confident73.8Confident58 Ų5872.7 Ų72.736%0.35641%0.408SS..Hα-helixtrans-62.1-36.5176.949.10000112.7F282 Q311 D312 S317 E318 T319F282-T315 HydrophobicContact CE2-CG2 3.91Å; F282-T315 HydrophobicContact CZ-CG2 3.74Å; Q311-T315 WeakPolarHBondContact O-CG2 3.24Å; Q311-T315 PolarHBondContact O-N 3.02Å; Q311-T315 PolarHBondContact O-OG1 3.49Å; D312-T315 PolarHBondContact O-OG1 2.97Å; D312-T315 VanDerWaalsContact O-OG1 3.05Å; T315-S317 VanDerWaalsContact C-N 3.33Å; T315-E318 PolarHBondContact O-N 3.39Å; T315-T319 WeakPolarHBondContact O-CG2 3.47Å; T315-T319 PolarHBondContact O-N 3.4Å; T315-T319 VanDerWaalsContact O-N 3.12Å; T315-T319 PolarHBondContact O-OG1 3.18Å
316L63.2Low72.4Confident105 Ų10572 Ų7255%0.5541%0.407SS..Hα-helixtrans-64.9-35.3171.7-70.9169.1000112.6D312 Y314 T319 Q320D312-L316 WeakPolarHBondContact O-CD1 3.43Å; D312-L316 VanDerWaalsContact O-CG 3.24Å; D312-L316 WeakPolarHBondContact O-CG 3.47Å; D312-L316 PolarHBondContact O-N 3.05Å; Y314-L316 VanDerWaalsContact C-N 3.31Å; Y314-L316 PolarHBondContact O-N 3.3Å; L316-T319 WeakPolarHBondContact CA-OG1 3.39Å; L316-T319 PolarHBondContact O-OG1 3.28Å; L316-T319 VanDerWaalsContact O-OG1 3.08Å; L316-Q320 WeakPolarHBondContact O-CB 3.21Å; L316-Q320 WeakPolarHBondContact O-CG 3.42Å; L316-Q320 PolarHBondContact O-N 3.08Å
317S64.4Low70.9Confident61 Ų6172 Ų7243%0.42741%0.414SS..Hα-helixtrans-74.8-35.217876.50000113.1S313 Y314 T315 Q320 A321S313-S317 PolarHBondContact O-N 2.94Å; Y314-S317 PolarHBondContact O-N 3.33Å; Y314-S317 PolarHBondContact O-OG 2.96Å; T315-S317 VanDerWaalsContact C-N 3.33Å; S317-Q320 PolarHBondContact O-N 3.12Å; S317-A321 WeakPolarHBondContact O-CB 3.45Å; S317-A321 PolarHBondContact O-N 2.79Å
318E63.1Low69.7Low87 Ų8776.7 Ų76.741%0.40744%0.439SS..Hα-helixtrans-71-44.2179.6-140.9169.4-154.600110.9Y314 T315 Q320 A321 E322Y314-E318 PolarHBondContact O-N 2.7Å; T315-E318 PolarHBondContact O-N 3.39Å; E318-Q320 VanDerWaalsContact C-N 3.33Å; E318-Q320 PolarHBondContact O-N 3.5Å; E318-A321 PolarHBondContact O-N 2.88Å; E318-A321 VanDerWaalsContact O-N 3.16Å; E318-E322 WeakPolarHBondContact O-CG 3.28Å; E318-E322 PolarHBondContact O-N 3.16Å
319T61.2Low68.4Low78 Ų7875.2 Ų75.248%0.47944%0.438SS..Hα-helixtrans-63.5-34.5174.447.20000113T315 L316 A323T315-T319 WeakPolarHBondContact O-CG2 3.47Å; T315-T319 PolarHBondContact O-N 3.4Å; T315-T319 VanDerWaalsContact O-N 3.12Å; T315-T319 PolarHBondContact O-OG1 3.18Å; L316-T319 WeakPolarHBondContact CA-OG1 3.39Å; L316-T319 PolarHBondContact O-OG1 3.28Å; L316-T319 VanDerWaalsContact O-OG1 3.08Å; T319-A323 VanDerWaalsContact O-CB 3.28Å; T319-A323 WeakPolarHBondContact O-CB 3.46Å; T319-A323 PolarHBondContact O-N 2.96Å
320Q58.8Low67.2Low138 Ų13876 Ų7665%0.64544%0.436SS*.Hα-helixtrans-71.3-36.7172.4-74.7175.36.200112.7L316 S317 E318 A324L316-Q320 WeakPolarHBondContact O-CB 3.21Å; L316-Q320 WeakPolarHBondContact O-CG 3.42Å; L316-Q320 PolarHBondContact O-N 3.08Å; S317-Q320 PolarHBondContact O-N 3.12Å; E318-Q320 VanDerWaalsContact C-N 3.33Å; E318-Q320 PolarHBondContact O-N 3.5Å; Q320-A324 VanDerWaalsContact O-CB 3.29Å; Q320-A324 WeakPolarHBondContact O-CB 3.29Å; Q320-A324 PolarHBondContact O-N 3.42Å
321A60.6Low66Low61 Ų6180.8 Ų80.850%0.50446%0.46SS..Hα-helixtrans-69-40.8176.400000112.1S317 E318 A324 A325S317-A321 WeakPolarHBondContact O-CB 3.45Å; S317-A321 PolarHBondContact O-N 2.79Å; E318-A321 PolarHBondContact O-N 2.88Å; E318-A321 VanDerWaalsContact O-N 3.16Å; A321-A324 PolarHBondContact O-N 3.06Å; A321-A325 WeakPolarHBondContact O-CB 3.47Å; A321-A325 PolarHBondContact O-N 2.98Å
322E60.9Low64.9Low129 Ų12984.2 Ų84.260%0.60348%0.479SS*.Hα-helixtrans-65-43.7173.7-73.2-17916400111.7E318 A324 A325 E326E318-E322 WeakPolarHBondContact O-CG 3.28Å; E318-E322 PolarHBondContact O-N 3.16Å; E322-A324 VanDerWaalsContact C-N 3.35Å; E322-A324 PolarHBondContact O-N 2.93Å; E322-A325 PolarHBondContact O-N 3.41Å; E322-E326 PolarHBondContact O-N 3.09Å
323A59.3Low63.7Low58 Ų5885.2 Ų85.248%0.47948%0.484SS..Hα-helixtrans-63.6-37.7175.200000112.8T319 A327T319-A323 VanDerWaalsContact O-CB 3.28Å; T319-A323 WeakPolarHBondContact O-CB 3.46Å; T319-A323 PolarHBondContact O-N 2.96Å; A323-A327 WeakPolarHBondContact O-CB 3.35Å; A323-A327 PolarHBondContact O-N 3.45Å
324A59.6Low62.8Low53 Ų5389.7 Ų89.744%0.43850%0.498SS..Hα-helixtrans-70.6-37.5175.400000112.5Q320 A321 E322 A327 L328Q320-A324 VanDerWaalsContact O-CB 3.29Å; Q320-A324 WeakPolarHBondContact O-CB 3.29Å; Q320-A324 PolarHBondContact O-N 3.42Å; A321-A324 PolarHBondContact O-N 3.06Å; E322-A324 VanDerWaalsContact C-N 3.35Å; E322-A324 PolarHBondContact O-N 2.93Å; A324-A327 PolarHBondContact O-N 3.31Å; A324-L328 WeakPolarHBondContact O-CB 3.45Å; A324-L328 PolarHBondContact O-N 2.92Å
325A60.6Low61.8Low61 Ų6191.8 Ų91.850%0.50452%0.52SS..Hα-helixtrans-67.6-40175.400000112A321 E322 S329A321-A325 WeakPolarHBondContact O-CB 3.47Å; A321-A325 PolarHBondContact O-N 2.98Å; E322-A325 PolarHBondContact O-N 3.41Å; A325-S329 WeakPolarHBondContact O-CB 3.41Å; A325-S329 PolarHBondContact O-N 2.99Å
326E62.9Low60.9Low120 Ų12097.1 Ų97.156%0.56154%0.543SS*.Hα-helixtrans-64.7-40.5172.2-82.8-164.6159.500112.3E322 S329 K330E322-E326 PolarHBondContact O-N 3.09Å; E326-S329 PolarHBondContact O-N 3.19Å; E326-S329 PolarHBondContact O-OG 3.05Å; E326-K330 WeakPolarHBondContact O-CG 3.41Å; E326-K330 PolarHBondContact O-N 3.09Å
327A61.4Low60.2Low49 Ų49101.1 Ų101.141%0.40557%0.571SS.*Hα-helixtrans-63.5-44.6176.300000112.3A323 A324 S329 K330 E331A323-A327 WeakPolarHBondContact O-CB 3.35Å; A323-A327 PolarHBondContact O-N 3.45Å; A324-A327 PolarHBondContact O-N 3.31Å; A327-S329 VanDerWaalsContact C-N 3.31Å; A327-S329 PolarHBondContact O-N 3.32Å; A327-K330 PolarHBondContact O-N 2.95Å; A327-E331 PolarHBondContact O-N 3.2Å
328L63.2Low60Low99 Ų99103.1 Ų103.152%0.51858%0.578SS.*Hα-helixtrans-63-35.7174.4-108.4138.7000112.6A324 N332A324-L328 WeakPolarHBondContact O-CB 3.45Å; A324-L328 PolarHBondContact O-N 2.92Å; L328-N332 WeakPolarHBondContact O-CB 3.42Å; L328-N332 VanDerWaalsContact O-CG 3.27Å; L328-N332 PolarHBondContact O-N 3.04Å; L328-N332 VanDerWaalsContact O-N 3.09Å; L328-N332 PolarHBondContact O-ND2 2.71Å; L328-N332 VanDerWaalsContact O-ND2 3.09Å
329S62.3Low59.8Low57 Ų57103.9 Ų103.940%0.39959%0.587SS.*Hα-helixtrans-67.8-35.7175.577.90000112.4A325 E326 A327 L333A325-S329 WeakPolarHBondContact O-CB 3.41Å; A325-S329 PolarHBondContact O-N 2.99Å; E326-S329 PolarHBondContact O-N 3.19Å; E326-S329 PolarHBondContact O-OG 3.05Å; A327-S329 VanDerWaalsContact C-N 3.31Å; A327-S329 PolarHBondContact O-N 3.32Å; S329-L333 PolarHBondContact O-N 3.43Å
330K63Low59.7Low122 Ų122105.4 Ų105.453%0.5359%0.593SS.*Hα-helixtrans-73-42.1176.9-73.8171.7-178.8164.40112E326 A327 N332 L333 E334E326-K330 WeakPolarHBondContact O-CG 3.41Å; E326-K330 PolarHBondContact O-N 3.09Å; A327-K330 PolarHBondContact O-N 2.95Å; K330-N332 PolarHBondContact O-N 2.93Å; K330-L333 PolarHBondContact O-N 3.23Å; K330-E334 WeakPolarHBondContact O-CG 3.47Å; K330-E334 PolarHBondContact O-N 3.48Å
331E63.3Low59.8Low129 Ų129103.5 Ų103.560%0.60359%0.59SS**Hα-helixtrans-62.1-41174-78.2-176.6159.700112.3A327 L333 E334 S335A327-E331 PolarHBondContact O-N 3.2Å; E331-L333 VanDerWaalsContact C-N 3.32Å; E331-L333 PolarHBondContact O-N 3.44Å; E331-E334 PolarHBondContact O-N 2.88Å; E331-S335 WeakPolarHBondContact O-CB 3.44Å; E331-S335 PolarHBondContact O-N 3.45Å; E331-S335 PolarHBondContact O-OG 3.36Å
332N61.9Low59.7Low97 Ų97106.1 Ų106.152%0.51960%0.595SS.*Hα-helixtrans-65.1-34.9176.1-75.9-31.9000112.4L328 K330 S335L328-N332 WeakPolarHBondContact O-CB 3.42Å; L328-N332 VanDerWaalsContact O-CG 3.27Å; L328-N332 PolarHBondContact O-N 3.04Å; L328-N332 VanDerWaalsContact O-N 3.09Å; L328-N332 PolarHBondContact O-ND2 2.71Å; L328-N332 VanDerWaalsContact O-ND2 3.09Å; K330-N332 PolarHBondContact O-N 2.93Å; N332-S335 PolarHBondContact O-OG 2.99Å
333L57.9Low59.7Low126 Ų126104.6 Ų104.666%0.6660%0.595SS**Hα-helixtrans-72-38175.1-98.6149.2000112.9S329 K330 E331 S335 M336S329-L333 PolarHBondContact O-N 3.43Å; K330-L333 PolarHBondContact O-N 3.23Å; E331-L333 VanDerWaalsContact C-N 3.32Å; E331-L333 PolarHBondContact O-N 3.44Å; L333-S335 VanDerWaalsContact C-N 3.35Å; L333-M336 PolarHBondContact O-N 3.44Å
334E60.7Low59.7Low150 Ų150107.9 Ų107.970%0.70160%0.603SS**Hα-helixtrans-72-28.1176.3-73.5-180175.200112.5K330 E331 M336K330-E334 WeakPolarHBondContact O-CG 3.47Å; K330-E334 PolarHBondContact O-N 3.48Å; E331-E334 PolarHBondContact O-N 2.88Å; E334-M336 PolarHBondContact O-N 3.33Å
335S56.8Low59.7Low90 Ų90112.2 Ų112.263%0.62962%0.616SS**THydrogen-bonded Turntrans-74.7-6.2175.473.90000115.2E331 N332 L333E331-S335 WeakPolarHBondContact O-CB 3.44Å; E331-S335 PolarHBondContact O-N 3.45Å; E331-S335 PolarHBondContact O-OG 3.36Å; N332-S335 PolarHBondContact O-OG 2.99Å; L333-S335 VanDerWaalsContact C-N 3.35Å
336M53.6Low59.6Low170 Ų170116.4 Ų116.484%0.83763%0.625SS**THydrogen-bonded Turntrans-1032.3179.8-82.9-176.463.600114.3L333 E334L333-M336 PolarHBondContact O-N 3.44Å; E334-M336 PolarHBondContact O-N 3.33Å
337V48.3Very low59.3Low188 Ų188116.1 Ų116.1100%1.13963%0.631SS**  trans-110.20174.9-178.80000109.9

Retrieved 337 of 337 residues in 611.1 ms (Link to these results)