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Hypoxia up-regulated protein 1

Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress. May play a role as a molecular chaperone and participate in protein folding.

AlphaFold DB , UniProt , Accession A0A087X054, Species HUMAN (Homo sapiens, Human), Gene HYOU1, Length 937 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M44.6Very low44.2Very low226 Ų226152.7 Ų152.7100%1.11370%0.701SS**  0-360-120.4172.3-177.600113.8D3 K4M1-D3 PolarHBondContact O-N 3.18Å; M1-K4 PolarHBondContact O-N 3.26Å
2A41Very low44.9Very low72 Ų72155.2 Ų155.260%0.59570%0.7SS**Hα-helixtrans-51.7-41.3-171.300000116.6K4 V5 R6A2-K4 VanDerWaalsContact C-N 3.33Å; A2-K4 PolarHBondContact O-N 3.17Å; A2-V5 WeakPolarHBondContact O-CB 3.4Å; A2-V5 PolarHBondContact O-N 3.24Å; A2-R6 PolarHBondContact O-N 3.17Å
3D41.2Very low45.8Very low115 Ų115159 Ų15962%0.61571%0.706SS**Hα-helixtrans-67.2-27.1-171.7-61.8-70.9000115.3M1 V5 R6 R7M1-D3 PolarHBondContact O-N 3.18Å; D3-V5 VanDerWaalsContact C-N 3.26Å; D3-V5 PolarHBondContact O-N 3.32Å; D3-R6 PolarHBondContact O-N 3.28Å; D3-R7 PolarHBondContact O-N 3.07Å
4K41.4Very low47.4Very low181 Ų181153.9 Ų153.979%0.78769%0.693SS**Hα-helixtrans-63.4-34.2171.5-86.5-171.1173.7-178.70111.5M1 A2M1-K4 PolarHBondContact O-N 3.26Å; A2-K4 VanDerWaalsContact C-N 3.33Å; A2-K4 PolarHBondContact O-N 3.17Å
5V45.2Very low48.8Very low84 Ų84148.7 Ų148.751%0.50968%0.681SS.*Hα-helixtrans-73.6-39.1177.7-174.60000111A2 D3 R7 Q8A2-V5 WeakPolarHBondContact O-CB 3.4Å; A2-V5 PolarHBondContact O-N 3.24Å; D3-V5 VanDerWaalsContact C-N 3.26Å; D3-V5 PolarHBondContact O-N 3.32Å; V5-R7 PolarHBondContact O-N 3.06Å; V5-Q8 PolarHBondContact O-N 3.06Å
6R43.1Very low50.4Low202 Ų202151 Ų15176%0.76268%0.683SS**Hα-helixtrans-63.9-40.2-179.1-128.5175.4-176.7176.6-0.2112.3A2 D3 Q8A2-R6 PolarHBondContact O-N 3.17Å; D3-R6 PolarHBondContact O-N 3.28Å; R6-Q8 PolarHBondContact O-N 2.78Å
7R43.9Very low51.8Low214 Ų214145.4 Ų145.481%0.80867%0.67SS**Hα-helixtrans-73.5-19.1178.4-72.1-173.5175.1-172.6-1.1115D3 V5D3-R7 PolarHBondContact O-N 3.07Å; V5-R7 PolarHBondContact O-N 3.06Å
8Q43.4Very low53Low126 Ų126142.9 Ų142.959%0.58966%0.662SS**Hα-helixtrans-83.8-27179.1-76.3-175.6-12.600114.3V5 R6 R11 R12V5-Q8 PolarHBondContact O-N 3.06Å; R6-Q8 PolarHBondContact O-N 2.78Å; Q8-R11 PolarHBondContact O-N 3.34Å; Q8-R12 PolarHBondContact O-N 2.99Å
9R44.9Very low54.5Low183 Ų183138.8 Ų138.869%0.69165%0.648SS**Hα-helixtrans-57-46.6-179.1-71.8-173176.3-161.9-1.7115R12 R13R9-R12 PolarHBondContact O-N 3.03Å; R9-R13 PolarHBondContact O-N 2.88Å; R9-R13 VanDerWaalsContact O-N 3.15Å
10P46.8Very low55.4Low74 Ų74134.8 Ų134.848%0.48164%0.639SS.*Hα-helixtrans-65.6-42.3177.924.1-33.2000112.1R12 R13 V14P10-R12 PolarHBondContact O-N 3.26Å; P10-R13 PolarHBondContact O-N 2.85Å; P10-R13 VanDerWaalsContact O-N 3.15Å; P10-V14 WeakPolarHBondContact O-CG2 3.19Å; P10-V14 PolarHBondContact O-N 2.87Å
11R50.8Low56.2Low203 Ų203132.2 Ų132.277%0.76663%0.632SS**Hα-helixtrans-59.2-43.3175.8-82.8-173.5170.3-174.9-3.6112.3Q8 R13 V14 C15Q8-R11 PolarHBondContact O-N 3.34Å; R11-R13 PolarHBondContact O-N 3.28Å; R11-V14 PolarHBondContact O-N 2.86Å; R11-C15 WeakPolarHBondContact O-CB 3.31Å; R11-C15 PolarHBondContact O-N 2.76Å; R11-C15 PolarHBondContact O-SG 3.26Å
12R52.3Low57.3Low182 Ų182126.1 Ų126.169%0.68760%0.603SS**Hα-helixtrans-61.2-41.7174.3-87-171.3170.7-171-2.8112.7Q8 R9 P10 C15 W16Q8-R12 PolarHBondContact O-N 2.99Å; R9-R12 PolarHBondContact O-N 3.03Å; P10-R12 PolarHBondContact O-N 3.26Å; R12-C15 PolarHBondContact O-N 3.4Å; R12-W16 PolarHBondContact O-N 2.7Å
13R57.4Low58.3Low205 Ų205127.3 Ų127.377%0.77460%0.599SS**Hα-helixtrans-64.9-40.9176.1-77-172.6171.2-172.3-4.6112.6R9 P10 R11 W16 A17R9-R13 PolarHBondContact O-N 2.88Å; R9-R13 VanDerWaalsContact O-N 3.15Å; P10-R13 PolarHBondContact O-N 2.85Å; P10-R13 VanDerWaalsContact O-N 3.15Å; R11-R13 PolarHBondContact O-N 3.28Å; R13-W16 PolarHBondContact O-N 2.74Å; R13-A17 WeakPolarHBondContact O-CB 3.41Å; R13-A17 PolarHBondContact O-N 3.43Å
14V67.9Low59.1Low88 Ų88124.4 Ų124.453%0.53359%0.591SS.*Hα-helixtrans-66.2-39.9175.6172.80000111.5P10 R11 A17 L18P10-V14 WeakPolarHBondContact O-CG2 3.19Å; P10-V14 PolarHBondContact O-N 2.87Å; R11-V14 PolarHBondContact O-N 2.86Å; V14-A17 PolarHBondContact O-N 3.42Å; V14-L18 HydrophobicContact CG1-CD1 4.07Å; V14-L18 WeakPolarHBondContact O-CB 3.37Å; V14-L18 PolarHBondContact O-N 2.68Å
15C68.1Low59.6Low75 Ų75119.6 Ų119.651%0.50757%0.574SS.*Hα-helixtrans-63.1-43.5172.4-71.10000112.5R11 R12 L18 V19R11-C15 WeakPolarHBondContact O-CB 3.31Å; R11-C15 PolarHBondContact O-N 2.76Å; R11-C15 PolarHBondContact O-SG 3.26Å; R12-C15 PolarHBondContact O-N 3.4Å; C15-L18 PolarHBondContact O-N 2.73Å; C15-V19 WeakPolarHBondContact O-CB 3.29Å; C15-V19 VanDerWaalsContact O-CG2 3.29Å; C15-V19 WeakPolarHBondContact O-CG2 3.39Å; C15-V19 PolarHBondContact O-N 3.49Å
16W75.1Confident59.8Low186 Ų186121.3 Ų121.371%0.70558%0.58SS**Hα-helixtrans-66.2-35.8175.7-81.7112.7000112.7R12 R13 A20R12-W16 PolarHBondContact O-N 2.7Å; R13-W16 PolarHBondContact O-N 2.74Å; W16-A20 VanDerWaalsContact O-CB 3.28Å; W16-A20 WeakPolarHBondContact O-CB 3.22Å; W16-A20 PolarHBondContact O-N 2.84Å
17A73.2Confident60.2Low56 Ų56117.8 Ų117.846%0.46358%0.576SS.*Hα-helixtrans-66.4-44.1172.600000111.9R13 V14 A20 V21R13-A17 WeakPolarHBondContact O-CB 3.41Å; R13-A17 PolarHBondContact O-N 3.43Å; V14-A17 PolarHBondContact O-N 3.42Å; A17-A20 PolarHBondContact O-N 3.44Å; A17-V21 WeakPolarHBondContact O-CB 3.41Å; A17-V21 WeakPolarHBondContact O-CG2 3.34Å; A17-V21 PolarHBondContact O-N 2.61Å
18L74.4Confident60.3Low101 Ų101111.6 Ų111.653%0.52957%0.57SS.*Hα-helixtrans-63.9-38.1174.4-86.7163.4000112.6V14 C15 L22V14-L18 HydrophobicContact CG1-CD1 4.07Å; V14-L18 WeakPolarHBondContact O-CB 3.37Å; V14-L18 PolarHBondContact O-N 2.68Å; C15-L18 PolarHBondContact O-N 2.73Å; L18-L22 VanDerWaalsContact O-CB 3.26Å; L18-L22 WeakPolarHBondContact O-CB 3.49Å; L18-L22 VanDerWaalsContact O-CG 3.27Å; L18-L22 WeakPolarHBondContact O-CG 3.01Å; L18-L22 PolarHBondContact O-N 3.31Å
19V79.9Confident60.4Low65 Ų65111.9 Ų111.939%0.39458%0.575SS.*Hα-helixtrans-69.3-37.3174.5167.20000111.2C15 L23C15-V19 WeakPolarHBondContact O-CB 3.29Å; C15-V19 VanDerWaalsContact O-CG2 3.29Å; C15-V19 WeakPolarHBondContact O-CG2 3.39Å; C15-V19 PolarHBondContact O-N 3.49Å; V19-L23 HydrophobicContact CG1-CD1 3.9Å; V19-L23 VanDerWaalsContact O-CB 3.27Å; V19-L23 WeakPolarHBondContact O-CB 3.49Å; V19-L23 VanDerWaalsContact O-CG 3.31Å; V19-L23 WeakPolarHBondContact O-CG 3.12Å; V19-L23 PolarHBondContact O-N 2.87Å
20A73Confident60.7Low58 Ų58106.5 Ų106.548%0.47957%0.565SS.*Hα-helixtrans-68.4-39.1174.400000112.4W16 A17 L23 A24W16-A20 VanDerWaalsContact O-CB 3.28Å; W16-A20 WeakPolarHBondContact O-CB 3.22Å; W16-A20 PolarHBondContact O-N 2.84Å; A17-A20 PolarHBondContact O-N 3.44Å; A20-L23 PolarHBondContact O-N 3Å; A20-A24 WeakPolarHBondContact O-CB 3.1Å; A20-A24 PolarHBondContact O-N 2.7Å
21V72.9Confident61.1Low80 Ų80109.4 Ų109.449%0.48558%0.576SS.*Hα-helixtrans-66.2-48.3172.5169.80000110.4A17 L23 A24 D25A17-V21 WeakPolarHBondContact O-CB 3.41Å; A17-V21 WeakPolarHBondContact O-CG2 3.34Å; A17-V21 PolarHBondContact O-N 2.61Å; V21-L23 VanDerWaalsContact C-N 3.28Å; V21-L23 PolarHBondContact O-N 3.3Å; V21-A24 CarbonylContact O-C 3.52Å; V21-A24 PolarHBondContact O-N 3.2Å; V21-A24 VanDerWaalsContact O-N 3.09Å; V21-D25 WeakPolarHBondContact CG1-OD2 3.45Å; V21-D25 WeakPolarHBondContact O-CB 3.49Å; V21-D25 VanDerWaalsContact O-CG 3.28Å; V21-D25 PolarHBondContact O-N 2.93Å
22L67.3Low61.9Low98 Ų98101.1 Ų101.151%0.51355%0.549SS..Hα-helixtrans-62.2-32.2176-77165.4000113.1L18 L26L18-L22 VanDerWaalsContact O-CB 3.26Å; L18-L22 WeakPolarHBondContact O-CB 3.49Å; L18-L22 VanDerWaalsContact O-CG 3.27Å; L18-L22 WeakPolarHBondContact O-CG 3.01Å; L18-L22 PolarHBondContact O-N 3.31Å; L22-L26 WeakPolarHBondContact O-CB 3.32Å; L22-L26 WeakPolarHBondContact O-CD1 3.46Å; L22-L26 VanDerWaalsContact O-CG 3.32Å; L22-L26 WeakPolarHBondContact O-CG 3.44Å; L22-L26 PolarHBondContact O-N 2.75Å
23L62.5Low63.5Low98 Ų9895.8 Ų95.851%0.51353%0.534SS..Hα-helixtrans-72.7-39.2172-81.6165.1000112.1V19 A20 V21 L26 L27V19-L23 HydrophobicContact CG1-CD1 3.9Å; V19-L23 VanDerWaalsContact O-CB 3.27Å; V19-L23 WeakPolarHBondContact O-CB 3.49Å; V19-L23 VanDerWaalsContact O-CG 3.31Å; V19-L23 WeakPolarHBondContact O-CG 3.12Å; V19-L23 PolarHBondContact O-N 2.87Å; A20-L23 PolarHBondContact O-N 3Å; V21-L23 VanDerWaalsContact C-N 3.28Å; V21-L23 PolarHBondContact O-N 3.3Å; L23-L26 PolarHBondContact O-N 2.82Å; L23-L27 WeakPolarHBondContact O-CB 3.41Å; L23-L27 WeakPolarHBondContact O-CD1 3.25Å; L23-L27 WeakPolarHBondContact O-CG 3.23Å; L23-L27 PolarHBondContact O-N 3.03Å
24A56.9Low65.2Low54 Ų5486 Ų8645%0.44650%0.497SS..Hα-helixtrans-65-41.8173.500000111.4A20 V21 L27 A28A20-A24 WeakPolarHBondContact O-CB 3.1Å; A20-A24 PolarHBondContact O-N 2.7Å; V21-A24 CarbonylContact O-C 3.52Å; V21-A24 PolarHBondContact O-N 3.2Å; V21-A24 VanDerWaalsContact O-N 3.09Å; A24-L27 PolarHBondContact O-N 3.49Å; A24-A28 VanDerWaalsContact O-CB 3.31Å; A24-A28 WeakPolarHBondContact O-CB 3.32Å; A24-A28 PolarHBondContact O-N 3.34Å
25D51.5Low66.5Low80 Ų8081.9 Ų81.943%0.42847%0.471SS..Hα-helixtrans-65.6-41.9173.9-68.2-27.1000111V21 L27 A28 L29V21-D25 WeakPolarHBondContact CG1-OD2 3.45Å; V21-D25 WeakPolarHBondContact O-CB 3.49Å; V21-D25 VanDerWaalsContact O-CG 3.28Å; V21-D25 PolarHBondContact O-N 2.93Å; D25-L27 VanDerWaalsContact C-N 3.34Å; D25-L27 PolarHBondContact O-N 2.98Å; D25-A28 CarbonylContact O-C 3.57Å; D25-A28 PolarHBondContact O-N 2.9Å; D25-L29 WeakPolarHBondContact O-CB 3.41Å; D25-L29 WeakPolarHBondContact O-CD1 3.44Å; D25-L29 WeakPolarHBondContact O-CG 3.24Å; D25-L29 PolarHBondContact O-N 3.16Å
26L50.7Low68Low119 Ų11978.3 Ų78.362%0.62345%0.447SS*.Hα-helixtrans-65.2-33.7174.1-87.8161000113.1L22 L23 L29 S30L22-L26 WeakPolarHBondContact O-CB 3.32Å; L22-L26 WeakPolarHBondContact O-CD1 3.46Å; L22-L26 VanDerWaalsContact O-CG 3.32Å; L22-L26 WeakPolarHBondContact O-CG 3.44Å; L22-L26 PolarHBondContact O-N 2.75Å; L23-L26 PolarHBondContact O-N 2.82Å; L26-L29 CarbonylContact O-C 3.59Å; L26-S30 PolarHBondContact O-N 3.35Å
27L50.7Low69.1Low129 Ų12969.4 Ų69.468%0.67541%0.414SS*.Hα-helixtrans-73.2-37.7172.7-72.3165.5000111.3L23 A24 D25 L29 S30L23-L27 WeakPolarHBondContact O-CB 3.41Å; L23-L27 WeakPolarHBondContact O-CD1 3.25Å; L23-L27 WeakPolarHBondContact O-CG 3.23Å; L23-L27 PolarHBondContact O-N 3.03Å; A24-L27 PolarHBondContact O-N 3.49Å; D25-L27 VanDerWaalsContact C-N 3.34Å; D25-L27 PolarHBondContact O-N 2.98Å; L27-L29 VanDerWaalsContact C-N 3.32Å; L27-S30 WeakPolarHBondContact O-CB 3.41Å; L27-S30 PolarHBondContact O-N 3.24Å; L27-S30 PolarHBondContact O-OG 3.47Å
28A47Very low70.3Confident83 Ų8366.8 Ų66.869%0.68639%0.392SS*.Hα-helixtrans-71.7-25.5173.800000113.3A24 D25 S30A24-A28 VanDerWaalsContact O-CB 3.31Å; A24-A28 WeakPolarHBondContact O-CB 3.32Å; A24-A28 PolarHBondContact O-N 3.34Å; D25-A28 CarbonylContact O-C 3.57Å; D25-A28 PolarHBondContact O-N 2.9Å; A28-S30 VanDerWaalsContact C-N 3.27Å
29L44.3Very low71.4Confident133 Ų13362.7 Ų62.770%0.69637%0.37SS*.THydrogen-bonded Turntrans-88.114.5170.5-70.8166.3000112.7D25 L26 L27 D31D25-L29 WeakPolarHBondContact O-CB 3.41Å; D25-L29 WeakPolarHBondContact O-CD1 3.44Å; D25-L29 WeakPolarHBondContact O-CG 3.24Å; D25-L29 PolarHBondContact O-N 3.16Å; L26-L29 CarbonylContact O-C 3.59Å; L27-L29 VanDerWaalsContact C-N 3.32Å; L29-D31 VanDerWaalsContact C-N 3.27Å; L29-D31 PolarHBondContact O-N 3.02Å
30S51.2Low72.3Confident69 Ų6960.5 Ų60.548%0.48336%0.356SS..  trans-67.995.4155.260.70000107.9L26 L27 A28 T32L26-S30 PolarHBondContact O-N 3.35Å; L27-S30 WeakPolarHBondContact O-CB 3.41Å; L27-S30 PolarHBondContact O-N 3.24Å; L27-S30 PolarHBondContact O-OG 3.47Å; A28-S30 VanDerWaalsContact C-N 3.27Å; S30-T32 PolarHBondContact O-N 2.98Å
31D56.6Low73.3Confident135 Ų13558.8 Ų58.872%0.72234%0.344SS*.  trans-50.1129.9164.3-89.8-37.7000107.8L29 L33L29-D31 VanDerWaalsContact C-N 3.27Å; L29-D31 PolarHBondContact O-N 3.02Å; D31-L33 VanDerWaalsContact C-N 3.26Å; D31-L33 HydrophobicContact CB-CD2 4.2Å; D31-L33 WeakPolarHBondContact O-CG 3.47Å; D31-L33 PolarHBondContact O-N 3.18Å
32T67.5Low74.4Confident30 Ų3055.9 Ų55.918%0.18433%0.327CS..  trans-7486.718051.30000108S30 A34 P168 K170S30-T32 PolarHBondContact O-N 2.98Å; T32-A34 VanDerWaalsContact C-N 3.32Å; T32-P168 WeakPolarHBondContact CB-O 3.18Å; T32-P168 HydrophobicContact CG2-CB 4.13Å; T32-P168 WeakPolarHBondContact CG2-O 3.36Å; T32-K170 HydrophobicContact CG2-CD 4.03Å; T32-K170 HydrophobicContact CG2-CG 4.35Å
33L85.5Confident75.7Confident70 Ų7054.1 Ų54.137%0.36632%0.316SS..  trans-72.2-27.4-173.8-64.5177.2000111.9D31 P52 A429 F430D31-L33 VanDerWaalsContact C-N 3.26Å; D31-L33 HydrophobicContact CB-CD2 4.2Å; D31-L33 WeakPolarHBondContact O-CG 3.47Å; D31-L33 PolarHBondContact O-N 3.18Å; L33-P52 HydrophobicContact CB-CG 3.55Å; L33-P52 HydrophobicContact CD1-CG 3.68Å; L33-P52 HydrophobicContact CG-CG 4.25Å; L33-A429 HydrophobicContact CB-CB 4.23Å; L33-A429 HydrophobicContact CD2-CB 3.68Å; L33-F430 WeakPolarHBondContact O-CE2 3.4Å; L33-F430 WeakPolarHBondContact O-CZ 3.37Å
34A93.3Very high77.3Confident0 Ų050.6 Ų50.60%030%0.3CS..  trans-66.8136.4172.800000112.2T32 I49 V50 K51 A165 Q167 I169T32-A34 VanDerWaalsContact C-N 3.32Å; A34-I49 HydrophobicContact CB-CD1 4.36Å; A34-V50 WeakPolarHBondContact CA-O 3.26Å; A34-K51 HydrophobicContact CB-CB 3.85Å; A34-A165 HydrophobicContact CB-CB 4.27Å; A34-Q167 HydrophobicContact CB-CG 3.94Å; A34-I169 HydrophobicContact CB-CD1 4.46Å; A34-I169 HydrophobicContact CB-CG1 4.19Å
35V95.9Very high79.3Confident0 Ų048.1 Ų48.10%028%0.279CS..EExtended strand (participates in β ladder)trans-127.4147.2169.5-56.40000110.5V50 D171 A423 F430V35-V50 HydrophobicContact CG2-CG1 3.68Å; V35-V50 PolarHBondContact N-O 3.13Å; V35-V50 VanDerWaalsContact N-O 3.13Å; V35-V50 PolarHBondContact O-N 3.15Å; V35-V50 VanDerWaalsContact O-N 3.08Å; V35-D171 HydrophobicContact CB-CB 4.49Å; V35-D171 HydrophobicContact CG1-CB 3.85Å; V35-A423 HydrophobicContact CB-CB 4.31Å; V35-A423 HydrophobicContact CG2-CB 3.72Å; V35-F430 HydrophobicContact CG1-CE2 4.36Å; V35-F430 HydrophobicContact CG2-CD2 4.23Å; V35-F430 HydrophobicContact CG2-CE2 3.86Å
36M97.7Very high81.5Confident0 Ų045.3 Ų45.30%026%0.263CS..EExtended strand (participates in β ladder)trans-115.1171.5-176.170.3-178.8-60.200112.4V38 V47 A48 S157 R158 A161 I169 D171 A172 V173 L197M36-V38 HydrophobicContact CE-CG2 3.81Å; M36-V47 HydrophobicContact CE-CG1 3.62Å; M36-A48 CarbonylContact C-O 3.6Å; M36-A48 VanDerWaalsContact CA-O 3.26Å; M36-A48 WeakPolarHBondContact CA-O 3.18Å; M36-S157 WeakPolarHBondContact CE-O 3.37Å; M36-R158 HydrophobicContact SD-CB 4.35Å; M36-R158 HydrophobicContact SD-CG 4.45Å; M36-A161 HydrophobicContact CB-CB 4.3Å; M36-A161 HydrophobicContact CE-CB 3.92Å; M36-A161 HydrophobicContact SD-CB 4.32Å; M36-I169 HydrophobicContact CB-CG2 4.12Å; M36-I169 HydrophobicContact CG-CG2 3.74Å; M36-I169 HydrophobicContact SD-CG2 3.73Å; M36-D171 PolarHBondContact N-O 3.24Å; M36-A172 HydrophobicContact CG-CB 3.57Å; M36-A172 VanDerWaalsContact O-CA 3.32Å; M36-A172 WeakPolarHBondContact O-CA 3.47Å; M36-A172 HydrophobicContact SD-CB 4.22Å; M36-V173 PolarHBondContact O-N 3.36Å; M36-V173 VanDerWaalsContact O-N 3.09Å; M36-L197 HydrophobicContact SD-CD2 4.06Å
37S98.6Very high83.8Confident0 Ų039.8 Ų39.80%024%0.235CC..EExtended strand (participates in β ladder)trans-141161.4158.970.60000111.9V47 A48 V173 A416 V420S37-V47 WeakPolarHBondContact O-CA 3.46Å; S37-A48 PolarHBondContact N-O 3.02Å; S37-A48 PolarHBondContact O-N 2.96Å; S37-V173 CarbonylContact C-O 3.46Å; S37-V173 WeakPolarHBondContact CA-O 3.4Å; S37-V173 WeakPolarHBondContact CB-O 3.2Å; S37-A416 PolarHBondContact OG-O 3.02Å; S37-V420 PolarHBondContact OG-N 2.95Å; S37-V420 VanDerWaalsContact OG-N 3.16Å
38V98.8Very high86Confident0 Ų033.7 Ų33.70%020%0.202CC..EExtended strand (participates in β ladder)trans-127.9115176.8-174.30000108.9M36 L40 M45 L154 V173 T175M36-V38 HydrophobicContact CE-CG2 3.81Å; V38-L40 HydrophobicContact CG1-CB 4.41Å; V38-L40 HydrophobicContact CG1-CD1 4.45Å; V38-L40 PolarHBondContact O-N 3.18Å; V38-M45 HydrophobicContact CG1-CB 4.37Å; V38-L154 HydrophobicContact CG1-CD2 4.4Å; V38-L154 HydrophobicContact CG2-CD2 4.3Å; V38-V173 PolarHBondContact N-O 2.84Å; V38-T175 PolarHBondContact O-N 2.9Å; V38-T175 PolarHBondContact O-OG1 3.09Å
39D98.6Very high88.4Confident15 Ų1529.8 Ų29.88%0.0817%0.17CC..EExtended strand (participates in β ladder)trans-72.8115155.6173.38.1000107.6G41 M45 K46 T175 A415 A416D39-G41 PolarHBondContact OD1-N 2.94Å; D39-M45 CarbonylContact O-C 3.6Å; D39-M45 WeakPolarHBondContact O-CA 3.32Å; D39-M45 WeakPolarHBondContact O-CB 3.37Å; D39-K46 HydrophobicContact CB-CB 4.43Å; D39-K46 HydrophobicContact CB-CD 3.97Å; D39-K46 PolarHBondContact N-O 3.12Å; D39-K46 PolarHBondContact O-N 2.85Å; D39-K46 VanDerWaalsContact O-N 3.1Å; D39-K46 WeakPolarHBondContact OD2-CD 3.47Å; D39-K46 WeakPolarHBondContact OD2-CE 3.39Å; D39-K46 IonicContact OD2-NZ 2.73Å; D39-K46 PolarHBondContact OD2-NZ 3.06Å; D39-T175 VanDerWaalsContact CA-OG1 3.32Å; D39-T175 WeakPolarHBondContact CA-OG1 3.39Å; D39-A415 HydrophobicContact CB-CB 4.34Å; D39-A416 HydrophobicContact CB-CB 3.91Å
40L96.9Very high90.8Very high20 Ų2023.9 Ų23.911%0.10514%0.14CC..EExtended strand (participates in β ladder)trans-104.949.5-171-169.760.5000111.7V38 L150 I174 T175V38-L40 HydrophobicContact CG1-CB 4.41Å; V38-L40 HydrophobicContact CG1-CD1 4.45Å; V38-L40 PolarHBondContact O-N 3.18Å; L40-L150 HydrophobicContact CD1-CD1 3.73Å; L40-L150 HydrophobicContact CD2-CD1 3.77Å; L40-L150 HydrophobicContact CD2-CD2 4.23Å; L40-L150 HydrophobicContact CG-CD1 4.34Å; L40-I174 HydrophobicContact CB-CG2 4.41Å; L40-I174 HydrophobicContact CD2-CG2 4.07Å; L40-T175 PolarHBondContact N-OG1 3.26Å
41G95.6Very high92.8Very high21 Ų2122 Ų2222%0.21612%0.123CC..  trans-57153.2175.200000114D39 E43 S44 V70 Q101D39-G41 PolarHBondContact OD1-N 2.94Å; G41-E43 PolarHBondContact O-N 2.97Å; G41-S44 WeakPolarHBondContact CA-O 3.43Å; G41-V70 WeakPolarHBondContact O-CG2 3.48Å; G41-Q101 PolarHBondContact O-NE2 2.97Å
42S95.1Very high94.2Very high19 Ų1918.9 Ų18.913%0.13311%0.11CC..SBendtrans-66-34.5-173.2-33.20000113.8Q101S42-Q101 PolarHBondContact O-NE2 3.32Å; S42-Q101 VanDerWaalsContact O-NE2 3.12Å
43E95.6Very high95Very high61 Ų6121.7 Ų21.729%0.28515%0.145SC..SBendtrans-97.9-42.2179.6174.9-179.2-157.500112.8G41 P69 V70 Y99 S235 N314G41-E43 PolarHBondContact O-N 2.97Å; E43-P69 WeakPolarHBondContact O-CA 3.39Å; E43-V70 PolarHBondContact O-N 2.81Å; E43-Y99 HydrophobicContact CB-CE1 4.43Å; E43-S235 WeakPolarHBondContact CB-OG 3.45Å; E43-S235 PolarHBondContact N-OG 3.04Å; E43-N314 PolarHBondContact OE1-ND2 2.69Å
44S96.4Very high95Very high25 Ų2520.5 Ų20.518%0.17514%0.141CC..EExtended strand (participates in β ladder)trans-144.6140.9-177.766.70000111.5G41 T68G41-S44 WeakPolarHBondContact CA-O 3.43Å; S44-T68 CarbonylContact C-O 3.49Å; S44-T68 VanDerWaalsContact CA-O 3.23Å; S44-T68 WeakPolarHBondContact CA-O 3.21Å; S44-T68 WeakPolarHBondContact CB-O 3.42Å
45M97.5Very high94.8Very high2 Ų225 Ų251%0.0117%0.17CC..EExtended strand (participates in β ladder)trans-100.8158.6172.764.5-177.5-166.800110.7V38 D39 T68 V70 V153 Y156 S157V38-M45 HydrophobicContact CG1-CB 4.37Å; D39-M45 CarbonylContact O-C 3.6Å; D39-M45 WeakPolarHBondContact O-CA 3.32Å; D39-M45 WeakPolarHBondContact O-CB 3.37Å; M45-T68 HydrophobicContact CE-CG2 3.7Å; M45-T68 HydrophobicContact CG-CG2 4.49Å; M45-T68 WeakPolarHBondContact CG-O 3.28Å; M45-T68 PolarHBondContact N-O 3.39Å; M45-T68 PolarHBondContact O-N 2.94Å; M45-V70 HydrophobicContact CB-CG2 3.66Å; M45-V70 HydrophobicContact CG-CG2 3.89Å; M45-V70 HydrophobicContact SD-CG2 4.34Å; M45-V153 HydrophobicContact CE-CG1 4.18Å; M45-V153 HydrophobicContact SD-CG1 3.44Å; M45-V153 WeakPolarHBondContact SD-CG1 3.47Å; M45-Y156 HydrophobicContact CE-CD1 3.85Å; M45-Y156 HydrophobicContact CE-CE1 4.26Å; M45-S157 VanDerWaalsContact CE-OG 3.23Å; M45-S157 WeakPolarHBondContact CE-OG 3.41Å; M45-S157 PolarHBondContact SD-OG 3.39Å
46K98.3Very high94.7Very high21 Ų2127.4 Ų27.49%0.09118%0.181CC..EExtended strand (participates in β ladder)trans-132.4141.9167.1-46.590.1-178.4-1700108D39 R66 K67 D412 A416D39-K46 HydrophobicContact CB-CB 4.43Å; D39-K46 HydrophobicContact CB-CD 3.97Å; D39-K46 PolarHBondContact N-O 3.12Å; D39-K46 PolarHBondContact O-N 2.85Å; D39-K46 VanDerWaalsContact O-N 3.1Å; D39-K46 WeakPolarHBondContact OD2-CD 3.47Å; D39-K46 WeakPolarHBondContact OD2-CE 3.39Å; D39-K46 IonicContact OD2-NZ 2.73Å; D39-K46 PolarHBondContact OD2-NZ 3.06Å; K46-R66 WeakPolarHBondContact CG-O 3.39Å; K46-K67 HydrophobicContact CD-CG 4.5Å; K46-K67 HydrophobicContact CG-CB 4.48Å; K46-K67 HydrophobicContact CG-CG 3.86Å; K46-D412 WeakPolarHBondContact CD-O 3.49Å; K46-D412 WeakPolarHBondContact CE-O 3.49Å; K46-D412 PolarHBondContact NZ-O 2.76Å; K46-A416 HydrophobicContact CB-CB 4.27Å
47V98.4Very high94.6Very high3 Ų331 Ų312%0.01820%0.198CC..EExtended strand (participates in β ladder)trans-111.5132-179.4178.80000107.3M36 S37 I58 V59 A161M36-V47 HydrophobicContact CE-CG1 3.62Å; S37-V47 WeakPolarHBondContact O-CA 3.46Å; V47-I58 CarbonylContact O-C 3.5Å; V47-I58 WeakPolarHBondContact O-CA 3.45Å; V47-V59 HydrophobicContact CB-CB 4.09Å; V47-V59 HydrophobicContact CG1-CB 4.09Å; V47-V59 HydrophobicContact CG1-CG2 4.02Å; V47-V59 PolarHBondContact O-N 3.35Å; V47-A161 HydrophobicContact CG1-CB 3.91Å
48A98.3Very high94.6Very high0 Ų031 Ų310%020%0.198CC..EExtended strand (participates in β ladder)trans-123.8147.3175.800000110.2M36 S37 E57 I58 A416 V420M36-A48 CarbonylContact C-O 3.6Å; M36-A48 VanDerWaalsContact CA-O 3.26Å; M36-A48 WeakPolarHBondContact CA-O 3.18Å; S37-A48 PolarHBondContact N-O 3.02Å; S37-A48 PolarHBondContact O-N 2.96Å; A48-E57 CarbonylContact C-O 3.5Å; A48-E57 VanDerWaalsContact CA-O 3.23Å; A48-E57 WeakPolarHBondContact CA-O 3.47Å; A48-I58 HydrophobicContact CB-CD1 3.78Å; A48-A416 HydrophobicContact CB-CB 3.94Å; A48-V420 HydrophobicContact CB-CB 3.9Å; A48-V420 HydrophobicContact CB-CG1 3.79Å
49I96.8Very high94.5Very high1 Ų131.2 Ų31.21%0.00520%0.2CC..EExtended strand (participates in β ladder)trans-135.7152.2-173.2-170.9170.3000111.4A34 M56 E57 V59 A161 F164 A165 I169A34-I49 HydrophobicContact CB-CD1 4.36Å; I49-M56 WeakPolarHBondContact O-CA 3.21Å; I49-E57 PolarHBondContact N-O 3.37Å; I49-E57 PolarHBondContact O-N 3.09Å; I49-V59 HydrophobicContact CB-CG2 3.85Å; I49-V59 HydrophobicContact CG2-CG2 3.51Å; I49-A161 HydrophobicContact CD1-CB 4.47Å; I49-F164 HydrophobicContact CD1-CD1 4.37Å; I49-F164 HydrophobicContact CG2-CD1 3.6Å; I49-F164 HydrophobicContact CG2-CE1 3.61Å; I49-A165 HydrophobicContact CD1-CB 3.56Å; I49-I169 HydrophobicContact CD1-CD1 3.73Å
50V95.1Very high94.4Very high10 Ų1034 Ų346%0.06121%0.214CC..EExtended strand (participates in β ladder)trans-131.4136.5158.462.70000109.1A34 V35 M56 V420 A424 F430A34-V50 WeakPolarHBondContact CA-O 3.26Å; V35-V50 HydrophobicContact CG2-CG1 3.68Å; V35-V50 PolarHBondContact N-O 3.13Å; V35-V50 VanDerWaalsContact N-O 3.13Å; V35-V50 PolarHBondContact O-N 3.15Å; V35-V50 VanDerWaalsContact O-N 3.08Å; V50-M56 HydrophobicContact CB-CG 3.96Å; V50-M56 HydrophobicContact CG2-CG 4.15Å; V50-V420 HydrophobicContact CB-CG2 4.24Å; V50-V420 HydrophobicContact CG1-CG2 4.03Å; V50-A424 HydrophobicContact CG1-CB 3.99Å; V50-F430 HydrophobicContact CB-CZ 4.36Å; V50-F430 HydrophobicContact CG1-CD2 4.15Å; V50-F430 HydrophobicContact CG1-CE1 4.25Å; V50-F430 HydrophobicContact CG1-CE2 3.71Å; V50-F430 HydrophobicContact CG1-CZ 3.77Å; V50-F430 HydrophobicContact CG2-CD1 4.25Å; V50-F430 HydrophobicContact CG2-CE1 3.79Å; V50-F430 HydrophobicContact CG2-CZ 4.06Å
51K92.1Very high94.3Very high30 Ų3033.4 Ų33.413%0.1321%0.211CC..EExtended strand (participates in β ladder)trans-135.8155.5175.173.1-175.3-170177.70110.1A34 G53 V54 F164 A165A34-K51 HydrophobicContact CB-CB 3.85Å; K51-G53 PolarHBondContact O-N 3.01Å; K51-V54 HydrophobicContact CD-CG2 4.31Å; K51-V54 HydrophobicContact CG-CB 3.78Å; K51-V54 HydrophobicContact CG-CG2 3.7Å; K51-V54 PolarHBondContact O-N 3.16Å; K51-F164 PolarHBondContact NZ-O 3.47Å; K51-A165 HydrophobicContact CD-CB 4.35Å; K51-A165 WeakPolarHBondContact CD-O 3.42Å; K51-A165 VanDerWaalsContact NZ-C 3.26Å; K51-A165 PolarHBondContact NZ-O 3.1Å
52P86.8Confident94.1Very high68 Ų6837.8 Ų37.844%0.44222%0.224SC..THydrogen-bonded Turntrans-52.1132.2-179.8-27.334.8000112.6L33 V54L33-P52 HydrophobicContact CB-CG 3.55Å; L33-P52 HydrophobicContact CD1-CG 3.68Å; L33-P52 HydrophobicContact CG-CG 4.25Å; P52-V54 VanDerWaalsContact C-N 3.27Å; P52-V54 PolarHBondContact O-N 3.05Å
53G84.8Confident94Very high90 Ų9039.9 Ų39.993%0.92823%0.232SC*.THydrogen-bonded Turntrans80.5-7.2-177.900000115.9K51K51-G53 PolarHBondContact O-N 3.01Å
54V85.2Confident94Very high45 Ų4541.4 Ų41.427%0.27325%0.249SC..EExtended strand (participates in β ladder)trans-120.1139-178.6-175.40000109.6K51 P52K51-V54 HydrophobicContact CD-CG2 4.31Å; K51-V54 HydrophobicContact CG-CB 3.78Å; K51-V54 HydrophobicContact CG-CG2 3.7Å; K51-V54 PolarHBondContact O-N 3.16Å; P52-V54 VanDerWaalsContact C-N 3.27Å; P52-V54 PolarHBondContact O-N 3.05Å
55P88.6Confident94Very high94 Ų9446.8 Ų46.861%0.6127%0.266SS*.EExtended strand (participates in β ladder)trans-65.3176.9174.229.2-36.6000112.4E57P55-E57 PolarHBondContact O-N 3.29Å
56M94.6Very high93.9Very high50 Ų5051.1 Ų51.125%0.24628%0.282CS..EExtended strand (participates in β ladder)trans-68.7127.3167.7-67.5161.6-173.900109.3I49 V50 M417 V420 Y421 A424 V432I49-M56 WeakPolarHBondContact O-CA 3.21Å; V50-M56 HydrophobicContact CB-CG 3.96Å; V50-M56 HydrophobicContact CG2-CG 4.15Å; M56-M417 HydrophobicContact CB-CE 3.83Å; M56-V420 HydrophobicContact CB-CG1 3.93Å; M56-V420 HydrophobicContact CG-CG1 3.98Å; M56-V420 HydrophobicContact SD-CG1 4.38Å; M56-Y421 HydrophobicContact CE-CD2 3.84Å; M56-Y421 HydrophobicContact CE-CG 4.28Å; M56-Y421 HydrophobicContact SD-CD2 3.81Å; M56-Y421 HydrophobicContact SD-CG 4.37Å; M56-A424 HydrophobicContact CE-CB 3.52Å; M56-V432 HydrophobicContact CE-CG1 3.8Å
57E95.3Very high93.8Very high77 Ų7754.5 Ų54.536%0.3630%0.297SS..EExtended strand (participates in β ladder)trans-145.1153.7-176.4-176.4160.2-156.800112.5A48 I49 P55 F164A48-E57 CarbonylContact C-O 3.5Å; A48-E57 VanDerWaalsContact CA-O 3.23Å; A48-E57 WeakPolarHBondContact CA-O 3.47Å; I49-E57 PolarHBondContact N-O 3.37Å; I49-E57 PolarHBondContact O-N 3.09Å; P55-E57 PolarHBondContact O-N 3.29Å; E57-F164 HydrophobicContact CG-CZ 4.32Å
58I97.8Very high93.8Very high0 Ų054.5 Ų54.50%030%0.297CS..EExtended strand (participates in β ladder)trans-79.6121.8171-56.2-56.5000109.9V47 A48 R66 E413 A416 M417V47-I58 CarbonylContact O-C 3.5Å; V47-I58 WeakPolarHBondContact O-CA 3.45Å; A48-I58 HydrophobicContact CB-CD1 3.78Å; I58-R66 HydrophobicContact CG2-CB 4Å; I58-R66 HydrophobicContact CG2-CG 4.34Å; I58-E413 HydrophobicContact CD1-CB 4.23Å; I58-E413 HydrophobicContact CD1-CG 4.35Å; I58-E413 HydrophobicContact CG1-CB 4.26Å; I58-E413 HydrophobicContact CG1-CG 3.98Å; I58-E413 WeakPolarHBondContact CG1-OE2 3.43Å; I58-A416 HydrophobicContact CD1-CB 3.89Å; I58-M417 HydrophobicContact CD1-CG 3.96Å; I58-M417 HydrophobicContact CD1-SD 3.59Å; I58-M417 VanDerWaalsContact CD1-SD 3.59Å; I58-M417 HydrophobicContact CG1-SD 4.06Å
59V97.2Very high93.7Very high4 Ų455.7 Ų55.72%0.02431%0.305CS..EExtended strand (participates in β ladder)trans-67.9132.5173.3175.50000109.9V47 I49 L160 A161 F164V47-V59 HydrophobicContact CB-CB 4.09Å; V47-V59 HydrophobicContact CG1-CB 4.09Å; V47-V59 HydrophobicContact CG1-CG2 4.02Å; V47-V59 PolarHBondContact O-N 3.35Å; I49-V59 HydrophobicContact CB-CG2 3.85Å; I49-V59 HydrophobicContact CG2-CG2 3.51Å; V59-L160 HydrophobicContact CG1-CB 3.99Å; V59-L160 VanDerWaalsContact CG1-O 3.31Å; V59-L160 WeakPolarHBondContact CG1-O 3.45Å; V59-A161 HydrophobicContact CG2-CB 4.37Å; V59-F164 HydrophobicContact CG1-CB 4.07Å; V59-F164 HydrophobicContact CG1-CG 4.5Å; V59-F164 HydrophobicContact CG2-CB 4.27Å; V59-F164 HydrophobicContact CG2-CD1 4.38Å; V59-F164 HydrophobicContact CG2-CG 4.21Å
60L96.6Very high93.8Very high72 Ų7255.7 Ų55.738%0.37731%0.305SS..PPolyproline II helixtrans-82148.4173.2-55.9-176.5000111.1R65 R66L60-R65 WeakPolarHBondContact CA-O 3.35Å; L60-R66 HydrophobicContact CD2-CB 4.39Å; L60-R66 HydrophobicContact CD2-CG 3.41Å; L60-R66 VanDerWaalsContact CD2-CG 3.41Å
61N94.6Very high93.9Very high8 Ų856.3 Ų56.34%0.04331%0.307CS..  trans-80178.7169.577.2-1.1000112.6E63 S64 R65 T68 D83 L160N61-E63 PolarHBondContact ND2-OE2 3.37Å; N61-E63 PolarHBondContact O-N 3.08Å; N61-E63 VanDerWaalsContact O-N 3.16Å; N61-E63 VanDerWaalsContact OD1-C 3.31Å; N61-E63 WeakPolarHBondContact OD1-CA 3.37Å; N61-E63 WeakPolarHBondContact OD1-CB 3.42Å; N61-E63 PolarHBondContact OD1-N 2.85Å; N61-E63 VanDerWaalsContact OD1-N 3.12Å; N61-S64 WeakPolarHBondContact O-CA 3.31Å; N61-S64 PolarHBondContact O-N 3.48Å; N61-S64 PolarHBondContact OD1-N 2.77Å; N61-R65 PolarHBondContact N-O 2.64Å; N61-R65 WeakPolarHBondContact OD1-CB 3.3Å; N61-R65 PolarHBondContact OD1-N 3.27Å; N61-T68 HydrophobicContact CB-CG2 4.5Å; N61-T68 WeakPolarHBondContact CB-OG1 3.43Å; N61-D83 PolarHBondContact ND2-OD2 3.34Å; N61-L160 HydrophobicContact CB-CD1 4.11Å
62K91.6Very high94.1Very high113 Ų11354.9 Ų54.949%0.49130%0.301SS..THydrogen-bonded Turntrans-62-23.1-178.6-67.8-172.3174-175.20112.7S64 L160K62-S64 VanDerWaalsContact C-N 3.34Å; K62-L160 HydrophobicContact CG-CD2 4.15Å
63E93Very high94.6Very high63 Ų6351.6 Ų51.629%0.29428%0.28SS..THydrogen-bonded Turntrans-92.214.9174.6-58.485.6166.700113.2N61 R65 D83 S84N61-E63 PolarHBondContact ND2-OE2 3.37Å; N61-E63 PolarHBondContact O-N 3.08Å; N61-E63 VanDerWaalsContact O-N 3.16Å; N61-E63 VanDerWaalsContact OD1-C 3.31Å; N61-E63 WeakPolarHBondContact OD1-CA 3.37Å; N61-E63 WeakPolarHBondContact OD1-CB 3.42Å; N61-E63 PolarHBondContact OD1-N 2.85Å; N61-E63 VanDerWaalsContact OD1-N 3.12Å; E63-R65 VanDerWaalsContact C-N 3.28Å; E63-R65 HydrophobicContact CB-CG 4.39Å; E63-R65 PolarHBondContact O-N 2.84Å; E63-D83 HydrophobicContact CG-CB 4.02Å; E63-S84 PolarHBondContact OE1-N 2.91Å; E63-S84 PolarHBondContact OE1-OG 2.91Å
64S95.8Very high94.9Very high94 Ų9448 Ų4866%0.65724%0.239SC*.SBendtrans60.623.7-179.3-59.90000115.7N61 K62N61-S64 WeakPolarHBondContact O-CA 3.31Å; N61-S64 PolarHBondContact O-N 3.48Å; N61-S64 PolarHBondContact OD1-N 2.77Å; K62-S64 VanDerWaalsContact C-N 3.34Å
65R95.7Very high94.9Very high137 Ų13748.8 Ų48.852%0.51724%0.239SC..  trans-96.1142.1-178.8-57.1176.4174.7-157-10.5111.7L60 N61 E63 K67 D83L60-R65 WeakPolarHBondContact CA-O 3.35Å; N61-R65 PolarHBondContact N-O 2.64Å; N61-R65 WeakPolarHBondContact OD1-CB 3.3Å; N61-R65 PolarHBondContact OD1-N 3.27Å; E63-R65 VanDerWaalsContact C-N 3.28Å; E63-R65 HydrophobicContact CB-CG 4.39Å; E63-R65 PolarHBondContact O-N 2.84Å; R65-K67 PolarHBondContact O-N 3.14Å; R65-D83 IonicContact CZ-OD1 2.9Å; R65-D83 IonicContact NE-OD1 3.41Å; R65-D83 IonicContact NH1-OD1 3.21Å; R65-D83 PolarHBondContact NH1-OD1 2.91Å
66R96.4Very high94.2Very high94 Ų9451.8 Ų51.836%0.35525%0.245SC..SBendtrans-76.3-2173.4-63.8174.977.683.9-8.5114K46 I58 L60 E413K46-R66 WeakPolarHBondContact CG-O 3.39Å; I58-R66 HydrophobicContact CG2-CB 4Å; I58-R66 HydrophobicContact CG2-CG 4.34Å; L60-R66 HydrophobicContact CD2-CB 4.39Å; L60-R66 HydrophobicContact CD2-CG 3.41Å; L60-R66 VanDerWaalsContact CD2-CG 3.41Å; R66-E413 IonicContact CZ-OE1 3.94Å; R66-E413 IonicContact CZ-OE2 2.79Å; R66-E413 IonicContact NE-OE1 2.7Å; R66-E413 PolarHBondContact NE-OE1 3.18Å; R66-E413 IonicContact NE-OE2 3.96Å; R66-E413 PolarHBondContact NE-OE2 2.67Å; R66-E413 IonicContact NH2-OE1 2.78Å; R66-E413 IonicContact NH2-OE2 3.47Å; R66-E413 PolarHBondContact NH2-OE2 2.88Å
67K95.5Very high93Very high91 Ų9153.6 Ų53.640%0.39626%0.256SS..  trans-137.2132.1179.4-66.1-175.5-68.8-173.60109.3K46 R65 D412K46-K67 HydrophobicContact CD-CG 4.5Å; K46-K67 HydrophobicContact CG-CB 4.48Å; K46-K67 HydrophobicContact CG-CG 3.86Å; R65-K67 PolarHBondContact O-N 3.14Å; K67-D412 HydrophobicContact CD-CB 4.24Å; K67-D412 WeakPolarHBondContact CD-OD2 3.44Å; K67-D412 WeakPolarHBondContact CE-OD2 3.47Å; K67-D412 IonicContact NZ-OD2 2.71Å; K67-D412 PolarHBondContact NZ-OD2 2.94Å
68T97.6Very high92.5Very high4 Ų452.6 Ų52.63%0.02525%0.251CS..EExtended strand (participates in β ladder)trans-117.9123.6-176.4-55.60000109.9S44 M45 N61 V70 Y156S44-T68 CarbonylContact C-O 3.49Å; S44-T68 VanDerWaalsContact CA-O 3.23Å; S44-T68 WeakPolarHBondContact CA-O 3.21Å; S44-T68 WeakPolarHBondContact CB-O 3.42Å; M45-T68 HydrophobicContact CE-CG2 3.7Å; M45-T68 HydrophobicContact CG-CG2 4.49Å; M45-T68 WeakPolarHBondContact CG-O 3.28Å; M45-T68 PolarHBondContact N-O 3.39Å; M45-T68 PolarHBondContact O-N 2.94Å; N61-T68 HydrophobicContact CB-CG2 4.5Å; N61-T68 WeakPolarHBondContact CB-OG1 3.43Å; T68-V70 PolarHBondContact O-N 3.45Å; T68-Y156 HydrophobicContact CG2-CE1 3.86Å
69P97.3Very high92.3Very high25 Ų2553.2 Ų53.216%0.16225%0.253CS..EExtended strand (participates in β ladder)trans-56.5131.7176.4-26.934.2000113.1E43 I71 D83 A86E43-P69 WeakPolarHBondContact O-CA 3.39Å; P69-I71 HydrophobicContact CB-CB 4.49Å; P69-I71 HydrophobicContact CB-CD1 4.05Å; P69-I71 HydrophobicContact CB-CG1 4.02Å; P69-I71 PolarHBondContact O-N 3.5Å; P69-D83 WeakPolarHBondContact CD-OD2 3.43Å; P69-A86 HydrophobicContact CG-CB 4.47Å
70V97.8Very high92.2Very high1 Ų154.9 Ų54.91%0.00626%0.26CS..  trans-8470.8173.8-173.60000109.2G41 E43 M45 T68 F100 Q101 V153G41-V70 WeakPolarHBondContact O-CG2 3.48Å; E43-V70 PolarHBondContact O-N 2.81Å; M45-V70 HydrophobicContact CB-CG2 3.66Å; M45-V70 HydrophobicContact CG-CG2 3.89Å; M45-V70 HydrophobicContact SD-CG2 4.34Å; T68-V70 PolarHBondContact O-N 3.45Å; V70-F100 HydrophobicContact CG1-CE1 3.9Å; V70-F100 HydrophobicContact CG1-CZ 3.76Å; V70-Q101 VanDerWaalsContact CG1-NE2 3.29Å; V70-V153 HydrophobicContact CG1-CG1 4.18Å; V70-V153 HydrophobicContact CG1-CG2 4.33Å
71I96.9Very high92.1Very high22 Ų2252.4 Ų52.411%0.11325%0.246CC..EExtended strand (participates in β ladder)trans-133.6133.1-177.5-55.3-177.3000107.8P69 A85 A86 T96 L97 R98P69-I71 HydrophobicContact CB-CB 4.49Å; P69-I71 HydrophobicContact CB-CD1 4.05Å; P69-I71 HydrophobicContact CB-CG1 4.02Å; P69-I71 PolarHBondContact O-N 3.5Å; I71-A85 HydrophobicContact CB-CB 4.05Å; I71-A85 HydrophobicContact CG2-CB 3.82Å; I71-A85 VanDerWaalsContact O-CB 3.28Å; I71-A85 WeakPolarHBondContact O-CB 3.32Å; I71-A86 HydrophobicContact CD1-CB 4.13Å; I71-T96 HydrophobicContact CG2-CG2 3.3Å; I71-L97 WeakPolarHBondContact CA-O 3.23Å; I71-R98 HydrophobicContact CG1-CB 4.19Å
72V97.3Very high92.2Very high0 Ų052.1 Ų52.10%025%0.245CC..EExtended strand (participates in β ladder)trans-121.4126.1174.7-173.60000108.3L74 F80 F81 T96 L97 V149 M152 V153V72-L74 HydrophobicContact CG1-CD2 3.8Å; V72-L74 HydrophobicContact CG1-CG 4.1Å; V72-F80 WeakPolarHBondContact CA-O 3.46Å; V72-F81 HydrophobicContact CG1-CD1 4.38Å; V72-F81 HydrophobicContact CG1-CE1 3.95Å; V72-F81 HydrophobicContact CG2-CD1 4.04Å; V72-F81 HydrophobicContact CG2-CE1 4Å; V72-T96 CarbonylContact O-C 3.44Å; V72-T96 WeakPolarHBondContact O-CA 3.14Å; V72-L97 PolarHBondContact N-O 2.68Å; V72-L97 PolarHBondContact O-N 3.24Å; V72-V149 HydrophobicContact CB-CG1 4.28Å; V72-V149 HydrophobicContact CG2-CG1 3.92Å; V72-M152 HydrophobicContact CG1-SD 4.11Å; V72-V153 HydrophobicContact CG2-CG2 3.45Å; V72-V153 VanDerWaalsContact CG2-CG2 3.45Å
73T96.4Very high92.3Very high0 Ų047.7 Ų47.70%023%0.227CC..EExtended strand (participates in β ladder)trans-110.3131169.6-56.30000110.6R79 F80 A85 M88 N92 A95 T96T73-R79 WeakPolarHBondContact O-CA 3.37Å; T73-F80 HydrophobicContact CG2-CD2 4.37Å; T73-F80 PolarHBondContact N-O 3.15Å; T73-F80 PolarHBondContact O-N 3.46Å; T73-A85 PolarHBondContact OG1-O 2.9Å; T73-M88 HydrophobicContact CG2-CB 4.08Å; T73-N92 HydrophobicContact CG2-CB 4.12Å; T73-A95 WeakPolarHBondContact CA-O 3.3Å; T73-T96 VanDerWaalsContact CG2-OG1 3.28Å; T73-T96 WeakPolarHBondContact CG2-OG1 3.46Å; T73-T96 WeakPolarHBondContact OG1-CB 3.48Å; T73-T96 WeakPolarHBondContact OG1-CG2 3.24Å; T73-T96 PolarHBondContact OG1-OG1 3.3Å
74L92.3Very high92.4Very high14 Ų1447.3 Ų47.37%0.07323%0.231CC..EExtended strand (participates in β ladder)trans-116.4100-174.9-60.3173.7000109.5V72 R79 A95 L97 I138 F144 M152V72-L74 HydrophobicContact CG1-CD2 3.8Å; V72-L74 HydrophobicContact CG1-CG 4.1Å; L74-R79 HydrophobicContact CD2-CB 4.33Å; L74-R79 HydrophobicContact CD2-CG 3.78Å; L74-A95 PolarHBondContact N-O 3.34Å; L74-A95 WeakPolarHBondContact O-CB 3.3Å; L74-L97 HydrophobicContact CD1-CD1 4.28Å; L74-I138 HydrophobicContact CB-CG2 3.95Å; L74-I138 HydrophobicContact CD1-CD1 4.1Å; L74-I138 HydrophobicContact CD1-CG1 3.89Å; L74-F144 HydrophobicContact CD1-CD2 3.71Å; L74-F144 HydrophobicContact CD1-CE2 3.75Å; L74-F144 HydrophobicContact CD1-CG 4.39Å; L74-F144 HydrophobicContact CD1-CZ 4.45Å; L74-M152 HydrophobicContact CD1-CE 4.49Å; L74-M152 HydrophobicContact CD2-CE 4.29Å; L74-M152 HydrophobicContact CD2-SD 3.99Å
75K85.3Confident92.4Very high61 Ų6142.9 Ų42.927%0.26520%0.2SC..EExtended strand (participates in β ladder)trans-128123.3-174.8178.8-179.6-174.1-80.80110N77 E78 F80 M88K75-N77 PolarHBondContact O-N 3.38Å; K75-N77 VanDerWaalsContact O-N 3.1Å; K75-E78 PolarHBondContact N-O 2.88Å; K75-E78 WeakPolarHBondContact O-CA 3.43Å; K75-E78 WeakPolarHBondContact O-CB 3.42Å; K75-E78 PolarHBondContact O-N 2.84Å; K75-F80 HydrophobicContact CB-CE2 4.26Å; K75-M88 HydrophobicContact CD-CE 3.72Å
76E73.8Confident92.3Very high158 Ų15838 Ų3874%0.73819%0.189SC*.THydrogen-bonded Turntrans53.834.6171-65.4151.1-159.700114.1E78E76-E78 VanDerWaalsContact C-N 3.28Å; E76-E78 PolarHBondContact O-N 3.12Å
77N69.9Low92.1Very high88 Ų8837.4 Ų37.447%0.47120%0.199SC..THydrogen-bonded Turntrans71.20.6-171.4-58.2-45.2000116.9K75 L142K75-N77 PolarHBondContact O-N 3.38Å; K75-N77 VanDerWaalsContact O-N 3.1Å; N77-L142 WeakPolarHBondContact OD1-CD1 3.4Å
78E83.3Confident92Very high56 Ų5634.5 Ų34.526%0.26219%0.188SC..EExtended strand (participates in β ladder)trans-85.1146.8167.8178.3171.7-178.200111.8K75 E76 F80 K671K75-E78 PolarHBondContact N-O 2.88Å; K75-E78 WeakPolarHBondContact O-CA 3.43Å; K75-E78 WeakPolarHBondContact O-CB 3.42Å; K75-E78 PolarHBondContact O-N 2.84Å; E76-E78 VanDerWaalsContact C-N 3.28Å; E76-E78 PolarHBondContact O-N 3.12Å; E78-F80 HydrophobicContact CB-CE2 4.36Å; E78-F80 HydrophobicContact CG-CD2 4.38Å; E78-F80 HydrophobicContact CG-CE1 4.5Å; E78-F80 HydrophobicContact CG-CE2 3.79Å; E78-F80 HydrophobicContact CG-CZ 3.85Å; E78-F80 VanDerWaalsContact OE1-CE1 3.27Å; E78-F80 WeakPolarHBondContact OE1-CE1 3.3Å; E78-F80 WeakPolarHBondContact OE1-CZ 3.5Å; E78-K671 IonicContact OE1-NZ 3.18Å; E78-K671 PolarHBondContact OE1-NZ 2.9Å; E78-K671 IonicContact OE2-NZ 3.4Å; E78-K671 PolarHBondContact OE2-NZ 3.47Å
79R93.4Very high91.8Very high13 Ų1334.6 Ų34.65%0.04919%0.188CC..EExtended strand (participates in β ladder)trans-113.6125.9174.8-52.9-172.3-65.4-170.32.9111.5T73 L74 F81 M152 T665 D668T73-R79 WeakPolarHBondContact O-CA 3.37Å; L74-R79 HydrophobicContact CD2-CB 4.33Å; L74-R79 HydrophobicContact CD2-CG 3.78Å; R79-F81 HydrophobicContact CB-CE2 3.68Å; R79-F81 HydrophobicContact CB-CZ 3.78Å; R79-M152 VanDerWaalsContact CD-SD 3.54Å; R79-T665 PolarHBondContact NH2-OG1 3.21Å; R79-D668 IonicContact CZ-OD2 3.46Å; R79-D668 IonicContact NE-OD2 3.98Å; R79-D668 PolarHBondContact NE-OD2 2.96Å; R79-D668 IonicContact NH2-OD2 3.47Å; R79-D668 PolarHBondContact NH2-OD2 2.91Å
80F95.1Very high91.6Very high38 Ų3834.4 Ų34.417%0.16719%0.186CC..EExtended strand (participates in β ladder)trans-104.9143.6167.9-54.9-94.2000110V72 T73 K75 E78 A85 M88V72-F80 WeakPolarHBondContact CA-O 3.46Å; T73-F80 HydrophobicContact CG2-CD2 4.37Å; T73-F80 PolarHBondContact N-O 3.15Å; T73-F80 PolarHBondContact O-N 3.46Å; K75-F80 HydrophobicContact CB-CE2 4.26Å; E78-F80 HydrophobicContact CB-CE2 4.36Å; E78-F80 HydrophobicContact CG-CD2 4.38Å; E78-F80 HydrophobicContact CG-CE1 4.5Å; E78-F80 HydrophobicContact CG-CE2 3.79Å; E78-F80 HydrophobicContact CG-CZ 3.85Å; E78-F80 VanDerWaalsContact OE1-CE1 3.27Å; E78-F80 WeakPolarHBondContact OE1-CE1 3.3Å; E78-F80 WeakPolarHBondContact OE1-CZ 3.5Å; F80-A85 HydrophobicContact CB-CB 4.11Å; F80-A85 WeakPolarHBondContact O-CB 3.41Å; F80-M88 HydrophobicContact CD1-CG 4.1Å; F80-M88 HydrophobicContact CD2-CE 4.31Å; F80-M88 HydrophobicContact CD2-CG 4.29Å; F80-M88 HydrophobicContact CE1-CE 4.31Å; F80-M88 HydrophobicContact CE1-CG 4.29Å; F80-M88 HydrophobicContact CE2-CE 3.7Å; F80-M88 HydrophobicContact CE2-CG 4.49Å; F80-M88 HydrophobicContact CG-CG 4.11Å; F80-M88 HydrophobicContact CZ-CE 3.71Å; F80-M88 HydrophobicContact CZ-CG 4.49Å
81F96.3Very high91.4Very high21 Ų2141.3 Ų41.39%0.09222%0.216CC..EExtended strand (participates in β ladder)trans-126.9166.2177-58.3-79.8000111.2V72 R79 S84 A85 M152 Y156V72-F81 HydrophobicContact CG1-CD1 4.38Å; V72-F81 HydrophobicContact CG1-CE1 3.95Å; V72-F81 HydrophobicContact CG2-CD1 4.04Å; V72-F81 HydrophobicContact CG2-CE1 4Å; R79-F81 HydrophobicContact CB-CE2 3.68Å; R79-F81 HydrophobicContact CB-CZ 3.78Å; F81-S84 WeakPolarHBondContact O-CB 3.13Å; F81-S84 PolarHBondContact O-N 2.89Å; F81-A85 VanDerWaalsContact C-CB 3.5Å; F81-A85 PolarHBondContact O-N 3.48Å; F81-M152 HydrophobicContact CE1-CB 3.72Å; F81-M152 HydrophobicContact CZ-CB 3.97Å; F81-Y156 HydrophobicContact CB-CD1 3.42Å; F81-Y156 VanDerWaalsContact CB-CD1 3.42Å; F81-Y156 HydrophobicContact CB-CD2 4.15Å; F81-Y156 HydrophobicContact CB-CE1 3.43Å; F81-Y156 VanDerWaalsContact CB-CE1 3.43Å; F81-Y156 HydrophobicContact CB-CE2 4.17Å; F81-Y156 HydrophobicContact CB-CG 3.79Å; F81-Y156 HydrophobicContact CD1-CD1 4.26Å; F81-Y156 HydrophobicContact CD1-CG 4.22Å; F81-Y156 HydrophobicContact CD2-CD2 4.02Å; F81-Y156 HydrophobicContact CD2-CG 4.02Å; F81-Y156 AromaticContact CG-CD1 3.83Å; F81-Y156 HydrophobicContact CG-CD1 3.83Å; F81-Y156 HydrophobicContact CG-CD2 4.14Å; F81-Y156 HydrophobicContact CG-CE1 4.3Å; F81-Y156 AromaticContact CG-CG 3.73Å; F81-Y156 HydrophobicContact CG-CG 3.73Å
82G95.6Very high91.3Very high1 Ų142 Ų421%0.0122%0.22CC..Hα-helixtrans59.2-140.4168.800000114.7S84 A85 A86G82-S84 VanDerWaalsContact C-N 3.27Å; G82-S84 PolarHBondContact O-N 2.89Å; G82-A85 WeakPolarHBondContact O-CB 3.34Å; G82-A85 PolarHBondContact O-N 3.26Å; G82-A85 VanDerWaalsContact O-N 3.14Å; G82-A86 PolarHBondContact O-N 2.99Å
83D94.8Very high91.2Very high21 Ų2142.6 Ų42.611%0.11222%0.223CC..Hα-helixtrans-65.6-30.5180-63.7-89.8000112.5N61 E63 R65 P69 A86 S87N61-D83 PolarHBondContact ND2-OD2 3.34Å; E63-D83 HydrophobicContact CG-CB 4.02Å; R65-D83 IonicContact CZ-OD1 2.9Å; R65-D83 IonicContact NE-OD1 3.41Å; R65-D83 IonicContact NH1-OD1 3.21Å; R65-D83 PolarHBondContact NH1-OD1 2.91Å; P69-D83 WeakPolarHBondContact CD-OD2 3.43Å; D83-A86 PolarHBondContact O-N 3.41Å; D83-S87 WeakPolarHBondContact O-CB 3.39Å; D83-S87 PolarHBondContact O-N 3.24Å; D83-S87 PolarHBondContact O-OG 3.09Å
84S94.2Very high91.1Very high55 Ų5549.1 Ų49.139%0.38525%0.252SS..Hα-helixtrans-63-41.7170.3-67.50000112.2E63 F81 G82 S87 M88E63-S84 PolarHBondContact OE1-N 2.91Å; E63-S84 PolarHBondContact OE1-OG 2.91Å; F81-S84 WeakPolarHBondContact O-CB 3.13Å; F81-S84 PolarHBondContact O-N 2.89Å; G82-S84 VanDerWaalsContact C-N 3.27Å; G82-S84 PolarHBondContact O-N 2.89Å; S84-S87 PolarHBondContact O-N 3.13Å; S84-M88 WeakPolarHBondContact O-CG 3.26Å; S84-M88 PolarHBondContact O-N 3.31Å; S84-M88 VanDerWaalsContact O-N 3.09Å
85A96Very high91.2Very high0 Ų049.2 Ų49.20%026%0.255CS..Hα-helixtrans-67.8-41.9172.100000112.6I71 T73 F80 F81 G82 S87 M88 A89I71-A85 HydrophobicContact CB-CB 4.05Å; I71-A85 HydrophobicContact CG2-CB 3.82Å; I71-A85 VanDerWaalsContact O-CB 3.28Å; I71-A85 WeakPolarHBondContact O-CB 3.32Å; T73-A85 PolarHBondContact OG1-O 2.9Å; F80-A85 HydrophobicContact CB-CB 4.11Å; F80-A85 WeakPolarHBondContact O-CB 3.41Å; F81-A85 VanDerWaalsContact C-CB 3.5Å; F81-A85 PolarHBondContact O-N 3.48Å; G82-A85 WeakPolarHBondContact O-CB 3.34Å; G82-A85 PolarHBondContact O-N 3.26Å; G82-A85 VanDerWaalsContact O-N 3.14Å; A85-S87 PolarHBondContact O-N 3.06Å; A85-M88 PolarHBondContact O-N 3.08Å; A85-M88 VanDerWaalsContact O-N 3.14Å; A85-A89 PolarHBondContact O-N 3.01Å
86A93.1Very high91.8Very high34 Ų3446.3 Ų46.328%0.28124%0.242SC..Hα-helixtrans-59.8-34.7175.600000112.1P69 I71 G82 D83 A89P69-A86 HydrophobicContact CG-CB 4.47Å; I71-A86 HydrophobicContact CD1-CB 4.13Å; G82-A86 PolarHBondContact O-N 2.99Å; D83-A86 PolarHBondContact O-N 3.41Å; A86-A89 VanDerWaalsContact O-CB 3.26Å; A86-A89 WeakPolarHBondContact O-CB 3.38Å
87S92.6Very high92.9Very high83 Ų8338.9 Ų38.958%0.5821%0.207SC*.Hα-helixtrans-71.2-38.3174.8-60.20000112.6D83 S84 A85 A89D83-S87 WeakPolarHBondContact O-CB 3.39Å; D83-S87 PolarHBondContact O-N 3.24Å; D83-S87 PolarHBondContact O-OG 3.09Å; S84-S87 PolarHBondContact O-N 3.13Å; A85-S87 PolarHBondContact O-N 3.06Å; S87-A89 VanDerWaalsContact C-N 3.32Å
88M93.9Very high94.2Very high30 Ų3035.9 Ų35.915%0.14819%0.19CC..Hα-helixtrans-75.4-18.7176.6-73.2-66.8-90.800113.8T73 K75 F80 S84 A85 I90 K91 N92T73-M88 HydrophobicContact CG2-CB 4.08Å; K75-M88 HydrophobicContact CD-CE 3.72Å; F80-M88 HydrophobicContact CD1-CG 4.1Å; F80-M88 HydrophobicContact CD2-CE 4.31Å; F80-M88 HydrophobicContact CD2-CG 4.29Å; F80-M88 HydrophobicContact CE1-CE 4.31Å; F80-M88 HydrophobicContact CE1-CG 4.29Å; F80-M88 HydrophobicContact CE2-CE 3.7Å; F80-M88 HydrophobicContact CE2-CG 4.49Å; F80-M88 HydrophobicContact CG-CG 4.11Å; F80-M88 HydrophobicContact CZ-CE 3.71Å; F80-M88 HydrophobicContact CZ-CG 4.49Å; S84-M88 WeakPolarHBondContact O-CG 3.26Å; S84-M88 PolarHBondContact O-N 3.31Å; S84-M88 VanDerWaalsContact O-N 3.09Å; A85-M88 PolarHBondContact O-N 3.08Å; A85-M88 VanDerWaalsContact O-N 3.14Å; M88-I90 VanDerWaalsContact C-N 3.27Å; M88-I90 PolarHBondContact O-N 2.81Å; M88-K91 PolarHBondContact O-N 3.05Å; M88-K91 HydrophobicContact SD-CD 4.03Å; M88-N92 WeakPolarHBondContact CE-ND2 3.17Å; M88-N92 PolarHBondContact O-N 3.01Å; M88-N92 PolarHBondContact O-ND2 2.99Å
89A93.6Very high94.8Very high5 Ų533.8 Ų33.84%0.04118%0.179CC..THydrogen-bonded Turntrans-54.5-34.2-179.400000115.2A85 A86 S87 P93 T96A85-A89 PolarHBondContact O-N 3.01Å; A86-A89 VanDerWaalsContact O-CB 3.26Å; A86-A89 WeakPolarHBondContact O-CB 3.38Å; S87-A89 VanDerWaalsContact C-N 3.32Å; A89-P93 WeakPolarHBondContact O-CA 3.42Å; A89-T96 WeakPolarHBondContact CA-OG1 3.37Å; A89-T96 HydrophobicContact CB-CG2 3.6Å
90I93.3Very high95Very high21 Ų2133.2 Ų33.211%0.10818%0.177CC..THydrogen-bonded Turntrans-77.8-28.4178-66.9170.4000111.1M88 R304 A307 K308M88-I90 VanDerWaalsContact C-N 3.27Å; M88-I90 PolarHBondContact O-N 2.81Å; I90-R304 HydrophobicContact CG2-CG 4.17Å; I90-R304 WeakPolarHBondContact O-CD 3.27Å; I90-R304 WeakPolarHBondContact O-CG 3.45Å; I90-A307 HydrophobicContact CG1-CB 4.23Å; I90-K308 HydrophobicContact CD1-CG 4.26Å; I90-K308 HydrophobicContact CG2-CG 3.77Å
91K93.6Very high95.1Very high147 Ų14731.9 Ų31.964%0.63917%0.171SC*.THydrogen-bonded Turntrans-83.4-35.5-179.5-65.5-179.9-177176.30112M88 P93M88-K91 PolarHBondContact O-N 3.05Å; M88-K91 HydrophobicContact SD-CD 4.03Å; K91-P93 VanDerWaalsContact C-CD 3.49Å
92N94.8Very high95Very high36 Ų3632.1 Ų32.119%0.19317%0.173CC..  trans-131.145.3-170.8-47.4-86000113.7T73 M88 K94 A95 T96T73-N92 HydrophobicContact CG2-CB 4.12Å; M88-N92 WeakPolarHBondContact CE-ND2 3.17Å; M88-N92 PolarHBondContact O-N 3.01Å; M88-N92 PolarHBondContact O-ND2 2.99Å; N92-K94 VanDerWaalsContact C-N 3.3Å; N92-K94 PolarHBondContact O-N 3.23Å; N92-K94 VanDerWaalsContact O-N 3.09Å; N92-A95 PolarHBondContact O-N 3.47Å; N92-T96 PolarHBondContact O-N 3.3Å; N92-T96 PolarHBondContact O-OG1 3.15Å
93P95Very high95.1Very high12 Ų1232.1 Ų32.18%0.07817%0.172CC..G310 helixtrans-53.2-40.7-166.120.3-33.6000114.4A89 K91 A95 T96 E122 H123 P303 A307A89-P93 WeakPolarHBondContact O-CA 3.42Å; K91-P93 VanDerWaalsContact C-CD 3.49Å; P93-A95 PolarHBondContact O-N 2.92Å; P93-A95 VanDerWaalsContact O-N 3.09Å; P93-T96 PolarHBondContact O-N 2.76Å; P93-T96 VanDerWaalsContact O-N 3.1Å; P93-E122 HydrophobicContact CB-CG 4.34Å; P93-H123 PolarHBondContact O-NE2 2.92Å; P93-P303 HydrophobicContact CB-CB 4.21Å; P93-P303 HydrophobicContact CG-CB 3.7Å; P93-A307 HydrophobicContact CB-CB 4.33Å
94K94.2Very high95.2Very high138 Ų13831.2 Ų31.260%0.617%0.168SC*.G310 helixtrans-56.9-24.4177-64.1-159.1167.7-161.10114.9N92 E122 H123N92-K94 VanDerWaalsContact C-N 3.3Å; N92-K94 PolarHBondContact O-N 3.23Å; N92-K94 VanDerWaalsContact O-N 3.09Å; K94-E122 HydrophobicContact CG-CB 4.39Å; K94-E122 WeakPolarHBondContact CG-O 3.47Å; K94-H123 PolarHBondContact O-CD2 2.92Å
95A94.2Very high95.2Very high16 Ų1629.1 Ų29.113%0.13216%0.155CC..G310 helixtrans-114.714.8-177.300000112.6T73 L74 N92 P93 I138T73-A95 WeakPolarHBondContact CA-O 3.3Å; L74-A95 PolarHBondContact N-O 3.34Å; L74-A95 WeakPolarHBondContact O-CB 3.3Å; N92-A95 PolarHBondContact O-N 3.47Å; P93-A95 PolarHBondContact O-N 2.92Å; P93-A95 VanDerWaalsContact O-N 3.09Å; A95-I138 HydrophobicContact CB-CG2 4.22Å
96T96.6Very high95.1Very high0 Ų029.3 Ų29.30%016%0.155CC..EExtended strand (participates in β ladder)trans-111.386.3179.9-60.80000111.4I71 V72 T73 A89 N92 P93 H123I71-T96 HydrophobicContact CG2-CG2 3.3Å; V72-T96 CarbonylContact O-C 3.44Å; V72-T96 WeakPolarHBondContact O-CA 3.14Å; T73-T96 VanDerWaalsContact CG2-OG1 3.28Å; T73-T96 WeakPolarHBondContact CG2-OG1 3.46Å; T73-T96 WeakPolarHBondContact OG1-CB 3.48Å; T73-T96 WeakPolarHBondContact OG1-CG2 3.24Å; T73-T96 PolarHBondContact OG1-OG1 3.3Å; A89-T96 WeakPolarHBondContact CA-OG1 3.37Å; A89-T96 HydrophobicContact CB-CG2 3.6Å; N92-T96 PolarHBondContact O-N 3.3Å; N92-T96 PolarHBondContact O-OG1 3.15Å; P93-T96 PolarHBondContact O-N 2.76Å; P93-T96 VanDerWaalsContact O-N 3.1Å; T96-H123 PolarHBondContact O-NE2 3.35Å
97L97.5Very high95.2Very high1 Ų130.8 Ų30.81%0.00516%0.157CC..EExtended strand (participates in β ladder)trans-72.5135.9-177.1-52.2-175.8000111.4I71 V72 L74 F100 F136 I138 V149I71-L97 WeakPolarHBondContact CA-O 3.23Å; V72-L97 PolarHBondContact N-O 2.68Å; V72-L97 PolarHBondContact O-N 3.24Å; L74-L97 HydrophobicContact CD1-CD1 4.28Å; L97-F100 HydrophobicContact CB-CD1 4.42Å; L97-F136 HydrophobicContact CD1-CB 3.99Å; L97-F136 HydrophobicContact CD1-CD1 4.3Å; L97-F136 HydrophobicContact CD1-CD2 3.69Å; L97-F136 HydrophobicContact CD1-CE2 4.2Å; L97-F136 HydrophobicContact CD1-CG 3.74Å; L97-F136 HydrophobicContact CD2-CB 4.12Å; L97-F136 HydrophobicContact CD2-CD1 3.51Å; L97-F136 HydrophobicContact CD2-CD2 4.42Å; L97-F136 HydrophobicContact CD2-CE1 3.93Å; L97-F136 HydrophobicContact CD2-CG 3.77Å; L97-F136 HydrophobicContact CG-CG 4.4Å; L97-I138 HydrophobicContact CD1-CD1 4.27Å; L97-I138 HydrophobicContact CD2-CD1 4.15Å; L97-I138 HydrophobicContact CG-CD1 4.36Å; L97-V149 HydrophobicContact CB-CG1 4.4Å; L97-V149 HydrophobicContact CD1-CB 4.49Å; L97-V149 HydrophobicContact CD1-CG1 4.08Å; L97-V149 HydrophobicContact CD1-CG2 3.56Å
98R96.5Very high95.3Very high26 Ų2628.6 Ų28.610%0.09814%0.143CC..EExtended strand (participates in β ladder)trans-154.9157-178.464.9-178.990-169.414.4109.8I71 F100 Y116 F120I71-R98 HydrophobicContact CG1-CB 4.19Å; R98-F100 PolarHBondContact O-N 2.81Å; R98-Y116 WeakPolarHBondContact O-CE2 3.48Å; R98-Y116 PolarHBondContact O-OH 2.96Å; R98-F120 HydrophobicContact CG-CD1 4.38Å; R98-F120 HydrophobicContact CG-CE1 4.02Å; R98-F120 HydrophobicContact CG-CZ 4.11Å
99Y97.4Very high95.3Very high12 Ų1233.7 Ų33.75%0.04717%0.171CC..SBendtrans51.917.9-179.2-66.3-84.4000114.7E43 Q101 H102 F120 S235 L273E43-Y99 HydrophobicContact CB-CE1 4.43Å; Y99-Q101 PolarHBondContact O-N 3.49Å; Y99-H102 AromaticContact CD1-CE1 3.83Å; Y99-H102 PolarHBondContact O-N 3.18Å; Y99-F120 HydrophobicContact CD2-CE2 4.2Å; Y99-F120 AromaticContact CD2-CZ 3.65Å; Y99-F120 HydrophobicContact CD2-CZ 3.65Å; Y99-F120 HydrophobicContact CE2-CZ 4.38Å; Y99-F120 HydrophobicContact CG-CE2 4.4Å; Y99-F120 HydrophobicContact CG-CZ 4.27Å; Y99-S235 WeakPolarHBondContact OH-CB 3.39Å; Y99-L273 HydrophobicContact CD1-CD2 3.81Å; Y99-L273 HydrophobicContact CD2-CD1 4.34Å; Y99-L273 HydrophobicContact CD2-CD2 3.99Å; Y99-L273 HydrophobicContact CE1-CB 4.03Å; Y99-L273 HydrophobicContact CE1-CD2 3.83Å; Y99-L273 HydrophobicContact CE1-CG 4.37Å; Y99-L273 HydrophobicContact CE2-CD1 3.78Å; Y99-L273 HydrophobicContact CE2-CD2 4.03Å; Y99-L273 HydrophobicContact CE2-CG 4.34Å; Y99-L273 HydrophobicContact CG-CD2 3.89Å
100F97Very high95.4Very high0 Ų034 Ų340%017%0.172CC..G310 helixtrans-67.1-16.1-178.658.2-94.2000112.1V70 L97 R98 H102 L103 F136 V149 L150 V153V70-F100 HydrophobicContact CG1-CE1 3.9Å; V70-F100 HydrophobicContact CG1-CZ 3.76Å; L97-F100 HydrophobicContact CB-CD1 4.42Å; R98-F100 PolarHBondContact O-N 2.81Å; F100-H102 PolarHBondContact O-N 2.97Å; F100-H102 VanDerWaalsContact O-N 3.15Å; F100-L103 WeakPolarHBondContact O-CB 3.2Å; F100-L103 PolarHBondContact O-N 2.91Å; F100-F136 HydrophobicContact CB-CE2 3.75Å; F100-F136 HydrophobicContact CB-CZ 3.51Å; F100-V149 HydrophobicContact CD1-CG1 3.83Å; F100-V149 HydrophobicContact CD2-CB 4.23Å; F100-V149 HydrophobicContact CD2-CG1 4.01Å; F100-V149 HydrophobicContact CE1-CG1 3.71Å; F100-V149 HydrophobicContact CE2-CB 4.27Å; F100-V149 HydrophobicContact CE2-CG1 3.9Å; F100-V149 HydrophobicContact CG-CG1 4Å; F100-V149 HydrophobicContact CZ-CG1 3.76Å; F100-L150 HydrophobicContact CE2-CB 3.97Å; F100-V153 HydrophobicContact CZ-CG2 3.99Å
101Q96.6Very high95.6Very high11 Ų1134.9 Ų34.95%0.05118%0.179CC..G310 helixtrans-55.3-27.9172.9-54.394.1-53.600112.1G41 S42 V70 Y99 L103 L104G41-Q101 PolarHBondContact O-NE2 2.97Å; S42-Q101 PolarHBondContact O-NE2 3.32Å; S42-Q101 VanDerWaalsContact O-NE2 3.12Å; V70-Q101 VanDerWaalsContact CG1-NE2 3.29Å; Y99-Q101 PolarHBondContact O-N 3.49Å; Q101-L103 PolarHBondContact O-N 3.49Å; Q101-L104 HydrophobicContact CB-CD1 4.1Å; Q101-L104 WeakPolarHBondContact O-CD1 3.45Å; Q101-L104 PolarHBondContact O-N 2.91Å
102H95.1Very high95.8Very high25 Ų2528.4 Ų28.412%0.11615%0.151CC..G310 helixtrans-69.1-11.9175.5-58.3158.3000114.2Y99 F100Y99-H102 AromaticContact CD1-CE1 3.83Å; Y99-H102 PolarHBondContact O-N 3.18Å; F100-H102 PolarHBondContact O-N 2.97Å; F100-H102 VanDerWaalsContact O-N 3.15Å
103L97.6Very high95.9Very high1 Ų127 Ų271%0.00514%0.144CC..G310 helixtrans-105.7-3.8-178.9-55178.4000113.2F100 Q101 G105 K106 V113 Y116 V134 F136 P146F100-L103 WeakPolarHBondContact O-CB 3.2Å; F100-L103 PolarHBondContact O-N 2.91Å; Q101-L103 PolarHBondContact O-N 3.49Å; L103-G105 PolarHBondContact O-N 3.35Å; L103-K106 PolarHBondContact O-N 3.43Å; L103-K106 VanDerWaalsContact O-N 3.08Å; L103-V113 HydrophobicContact CD2-CB 4.41Å; L103-V113 HydrophobicContact CD2-CG2 4.1Å; L103-Y116 HydrophobicContact CD1-CD1 3.91Å; L103-Y116 HydrophobicContact CD1-CD2 3.9Å; L103-Y116 HydrophobicContact CD1-CE1 4.2Å; L103-Y116 HydrophobicContact CD1-CE2 4.19Å; L103-Y116 HydrophobicContact CD1-CG 3.77Å; L103-Y116 HydrophobicContact CD2-CD2 4.35Å; L103-Y116 HydrophobicContact CD2-CG 4.06Å; L103-Y116 HydrophobicContact CG-CD2 4.03Å; L103-Y116 HydrophobicContact CG-CG 4.11Å; L103-V134 HydrophobicContact CD1-CG1 4.16Å; L103-V134 HydrophobicContact CD2-CG2 4.48Å; L103-F136 HydrophobicContact CD1-CE1 4.14Å; L103-F136 HydrophobicContact CD1-CZ 3.7Å; L103-P146 HydrophobicContact CB-CB 4.22Å; L103-P146 HydrophobicContact CB-CG 3.69Å
104L96.8Very high96Very high2 Ų229.8 Ų29.81%0.0117%0.168CC..THydrogen-bonded Turntrans-57.9123.9177.1-69.8166.4000109.9Q101 K106 P146 E147 L150 F180 A187 V188Q101-L104 HydrophobicContact CB-CD1 4.1Å; Q101-L104 WeakPolarHBondContact O-CD1 3.45Å; Q101-L104 PolarHBondContact O-N 2.91Å; L104-K106 VanDerWaalsContact C-N 3.25Å; L104-K106 PolarHBondContact O-N 3.14Å; L104-P146 HydrophobicContact CD2-CB 4.01Å; L104-P146 HydrophobicContact CG-CB 4.46Å; L104-E147 HydrophobicContact CD2-CG 4.23Å; L104-L150 HydrophobicContact CD1-CD2 3.89Å; L104-L150 HydrophobicContact CD2-CB 4.37Å; L104-L150 HydrophobicContact CD2-CD2 3.97Å; L104-F180 HydrophobicContact CD1-CE2 4.29Å; L104-F180 HydrophobicContact CD1-CZ 4.44Å; L104-A187 HydrophobicContact CB-CB 4.04Å; L104-A187 HydrophobicContact CD2-CB 4.29Å; L104-V188 HydrophobicContact CD1-CG2 4.1Å
105G93.3Very high96.2Very high11 Ų1125.8 Ų25.811%0.11315%0.153CC..THydrogen-bonded Turntrans64.721.3-178.600000115.2L103 L646L103-G105 PolarHBondContact O-N 3.35Å; G105-L646 VanDerWaalsContact CA-CD2 3.5Å
106K94.9Very high96.4Very high4 Ų425.2 Ų25.22%0.01715%0.147CC..  trans-102.1135.7178.9-58.1-52.4-178.4-174.60113L103 L104 N110 V113 T133 E184 V510L103-K106 PolarHBondContact O-N 3.43Å; L103-K106 VanDerWaalsContact O-N 3.08Å; L104-K106 VanDerWaalsContact C-N 3.25Å; L104-K106 PolarHBondContact O-N 3.14Å; K106-N110 HydrophobicContact CB-CB 4.33Å; K106-N110 HydrophobicContact CD-CB 4.5Å; K106-V113 HydrophobicContact CB-CG2 4.08Å; K106-T133 WeakPolarHBondContact O-CA 3.07Å; K106-E184 WeakPolarHBondContact CE-OE1 3.38Å; K106-E184 IonicContact NZ-OE1 3.35Å; K106-E184 PolarHBondContact NZ-OE1 3.09Å; K106-V510 PolarHBondContact NZ-O 3.35Å
107Q94.5Very high96.4Very high66 Ų6628.3 Ų28.331%0.30816%0.162SC..BIsolated β-bridgetrans-90.8161.5172.8-64-175.6-54.800111.5D109 N110 V113 R131 Q132 L646Q107-D109 PolarHBondContact O-N 2.72Å; Q107-D109 VanDerWaalsContact O-N 3.12Å; Q107-N110 VanDerWaalsContact O-CB 3.27Å; Q107-N110 WeakPolarHBondContact O-CB 3.45Å; Q107-N110 PolarHBondContact O-N 3.2Å; Q107-V113 WeakPolarHBondContact O-CG2 3.49Å; Q107-R131 PolarHBondContact NE2-O 3.12Å; Q107-Q132 CarbonylContact C-O 3.53Å; Q107-Q132 VanDerWaalsContact CA-O 3.26Å; Q107-Q132 WeakPolarHBondContact CA-O 3.47Å; Q107-L646 HydrophobicContact CG-CD1 4.09Å
108A94.6Very high96.4Very high36 Ų3631.8 Ų31.830%0.29819%0.19SC..THydrogen-bonded Turntrans-53.5-31.1-170.700000116F127 Q132A108-F127 HydrophobicContact CB-CD1 3.43Å; A108-F127 VanDerWaalsContact CB-CD1 3.43Å; A108-F127 HydrophobicContact CB-CD2 4.19Å; A108-F127 HydrophobicContact CB-CE1 3.44Å; A108-F127 VanDerWaalsContact CB-CE1 3.44Å; A108-F127 HydrophobicContact CB-CE2 4.2Å; A108-F127 HydrophobicContact CB-CG 3.83Å; A108-F127 HydrophobicContact CB-CZ 3.84Å; A108-Q132 PolarHBondContact N-O 3.28Å
109D94.2Very high96.5Very high137 Ų13731.3 Ų31.373%0.73319%0.189SC*.THydrogen-bonded Turntrans-86.1-8.9-178.166.5-31.4000113.9Q107Q107-D109 PolarHBondContact O-N 2.72Å; Q107-D109 VanDerWaalsContact O-N 3.12Å
110N96.5Very high96.4Very high12 Ų1230.8 Ų30.86%0.06419%0.187CC..SBendtrans-69.6133.4-175.9-169.9-80.2000111.6K106 Q107 H112 V113 R509 V510K106-N110 HydrophobicContact CB-CB 4.33Å; K106-N110 HydrophobicContact CD-CB 4.5Å; Q107-N110 VanDerWaalsContact O-CB 3.27Å; Q107-N110 WeakPolarHBondContact O-CB 3.45Å; Q107-N110 PolarHBondContact O-N 3.2Å; N110-H112 PolarHBondContact O-N 3.13Å; N110-H112 PolarHBondContact OD1-N 3.36Å; N110-H112 VanDerWaalsContact OD1-N 3.12Å; N110-V113 HydrophobicContact CB-CG2 4.28Å; N110-V113 WeakPolarHBondContact O-CB 3.43Å; N110-V113 PolarHBondContact O-N 2.89Å; N110-R509 PolarHBondContact ND2-O 3.49Å; N110-V510 PolarHBondContact ND2-O 2.87Å
111P97.2Very high96.4Very high40 Ų4034.9 Ų34.926%0.2621%0.214SC..Hα-helixtrans-56.5-27-176.7-26.533.7000115V113 A114 L115 R509 V510P111-V113 VanDerWaalsContact C-N 3.3Å; P111-V113 PolarHBondContact O-N 3.11Å; P111-A114 PolarHBondContact O-N 2.94Å; P111-L115 WeakPolarHBondContact O-CB 3.48Å; P111-L115 PolarHBondContact O-N 3.21Å; P111-R509 HydrophobicContact CG-CB 3.75Å; P111-V510 HydrophobicContact CB-CG2 4.04Å; P111-V510 HydrophobicContact CG-CG2 4.25Å
112H96.6Very high96.3Very high11 Ų1135.4 Ų35.45%0.05122%0.216CC..Hα-helixtrans-69.5-22.9176.3-87.4-143.7000113.9N110 Y116 V510N110-H112 PolarHBondContact O-N 3.13Å; N110-H112 PolarHBondContact OD1-N 3.36Å; N110-H112 VanDerWaalsContact OD1-N 3.12Å; H112-Y116 WeakPolarHBondContact O-CB 3.46Å; H112-Y116 PolarHBondContact O-N 3.21Å; H112-V510 VanDerWaalsContact CD2-CG2 3.42Å; H112-V510 WeakPolarHBondContact CD2-CG2 3.45Å
113V97.9Very high96.4Very high7 Ų734.4 Ų34.44%0.04221%0.211CC..Hα-helixtrans-70-48.5173-176.40000110.1L103 K106 Q107 N110 P111 L115 Y116 Q117 L125 F127 V134L103-V113 HydrophobicContact CD2-CB 4.41Å; L103-V113 HydrophobicContact CD2-CG2 4.1Å; K106-V113 HydrophobicContact CB-CG2 4.08Å; Q107-V113 WeakPolarHBondContact O-CG2 3.49Å; N110-V113 HydrophobicContact CB-CG2 4.28Å; N110-V113 WeakPolarHBondContact O-CB 3.43Å; N110-V113 PolarHBondContact O-N 2.89Å; P111-V113 VanDerWaalsContact C-N 3.3Å; P111-V113 PolarHBondContact O-N 3.11Å; V113-L115 PolarHBondContact O-N 3.32Å; V113-Y116 PolarHBondContact O-N 3.06Å; V113-Q117 PolarHBondContact O-N 3.21Å; V113-L125 HydrophobicContact CG1-CD1 4.12Å; V113-F127 HydrophobicContact CG1-CE1 4.21Å; V113-V134 HydrophobicContact CB-CG2 4.42Å; V113-V134 HydrophobicContact CG1-CG2 3.85Å; V113-V134 HydrophobicContact CG2-CG2 3.65Å
114A97.7Very high96.3Very high69 Ų6940.1 Ų40.157%0.5724%0.238SC*.Hα-helixtrans-61.3-42.4174.800000112P111 Y116 Q117 A118P111-A114 PolarHBondContact O-N 2.94Å; A114-Y116 PolarHBondContact O-N 3.39Å; A114-Q117 PolarHBondContact O-N 2.66Å; A114-A118 WeakPolarHBondContact O-CB 3.32Å; A114-A118 PolarHBondContact O-N 2.97Å
115L97.8Very high96.3Very high55 Ų5541.2 Ų41.229%0.28824%0.243SC..Hα-helixtrans-63.4-38.5175.5-178.759.7000112.3P111 V113 A118 R119 T269P111-L115 WeakPolarHBondContact O-CB 3.48Å; P111-L115 PolarHBondContact O-N 3.21Å; V113-L115 PolarHBondContact O-N 3.32Å; L115-A118 PolarHBondContact O-N 3Å; L115-R119 HydrophobicContact CD1-CG 4.45Å; L115-R119 VanDerWaalsContact O-CG 3.23Å; L115-R119 WeakPolarHBondContact O-CG 3.24Å; L115-R119 PolarHBondContact O-N 3.19Å; L115-R119 VanDerWaalsContact O-N 3.13Å; L115-T269 HydrophobicContact CD2-CG2 3.71Å
116Y98.3Very high96.4Very high4 Ų442.6 Ų42.62%0.01625%0.25CC..Hα-helixtrans-63.3-48.5173.8-175.7-82.3000111.4R98 L103 H112 V113 A114 A118 R119 F120 H123 L125 F136R98-Y116 WeakPolarHBondContact O-CE2 3.48Å; R98-Y116 PolarHBondContact O-OH 2.96Å; L103-Y116 HydrophobicContact CD1-CD1 3.91Å; L103-Y116 HydrophobicContact CD1-CD2 3.9Å; L103-Y116 HydrophobicContact CD1-CE1 4.2Å; L103-Y116 HydrophobicContact CD1-CE2 4.19Å; L103-Y116 HydrophobicContact CD1-CG 3.77Å; L103-Y116 HydrophobicContact CD2-CD2 4.35Å; L103-Y116 HydrophobicContact CD2-CG 4.06Å; L103-Y116 HydrophobicContact CG-CD2 4.03Å; L103-Y116 HydrophobicContact CG-CG 4.11Å; H112-Y116 WeakPolarHBondContact O-CB 3.46Å; H112-Y116 PolarHBondContact O-N 3.21Å; V113-Y116 PolarHBondContact O-N 3.06Å; A114-Y116 PolarHBondContact O-N 3.39Å; Y116-A118 VanDerWaalsContact C-N 3.27Å; Y116-A118 PolarHBondContact O-N 2.94Å; Y116-R119 PolarHBondContact O-N 3.32Å; Y116-R119 VanDerWaalsContact O-N 3.09Å; Y116-F120 HydrophobicContact CD1-CD2 4.37Å; Y116-F120 HydrophobicContact CD2-CD2 4Å; Y116-F120 HydrophobicContact CD2-CE2 4.35Å; Y116-F120 HydrophobicContact CE1-CB 4.18Å; Y116-F120 HydrophobicContact CE1-CD2 4.06Å; Y116-F120 AromaticContact CE2-CD2 3.67Å; Y116-F120 HydrophobicContact CE2-CD2 3.67Å; Y116-F120 HydrophobicContact CE2-CE2 4.03Å; Y116-F120 HydrophobicContact CG-CD2 4.32Å; Y116-F120 AromaticContact CZ-CD2 3.68Å; Y116-F120 PolarHBondContact O-N 3.08Å; Y116-H123 HydrophobicContact CE1-CB 4.48Å; Y116-H123 AromaticContact CE1-ND1 3.61Å; Y116-H123 AromaticContact CZ-ND1 3.71Å; Y116-H123 PolarHBondContact OH-CE1 3.35Å; Y116-H123 PolarHBondContact OH-ND1 2.92Å; Y116-L125 HydrophobicContact CD1-CD1 4.32Å; Y116-F136 AromaticContact CE1-CE1 3.76Å; Y116-F136 HydrophobicContact CE1-CE1 3.76Å; Y116-F136 HydrophobicContact CE1-CZ 4.41Å; Y116-F136 AromaticContact CZ-CE1 3.83Å
117Q97.6Very high96.5Very high64 Ų6446.4 Ų46.430%0.29927%0.266SS..Hα-helixtrans-60.8-35.5179.3-169.969.272.900112.2V113 A114 F120 P121 H123 L125V113-Q117 PolarHBondContact O-N 3.21Å; A114-Q117 PolarHBondContact O-N 2.66Å; Q117-F120 CarbonylContact O-C 3.56Å; Q117-P121 VanDerWaalsContact O-CA 3.28Å; Q117-P121 WeakPolarHBondContact O-CA 3.45Å; Q117-P121 VanDerWaalsContact O-N 3.16Å; Q117-H123 PolarHBondContact NE2-O 3.12Å; Q117-L125 VanDerWaalsContact OE1-CG 3.3Å
118A97.4Very high96.4Very high74 Ų7444.9 Ų44.961%0.61226%0.261SS*.Hα-helixtrans-70-33.8174.900000113.1A114 L115 Y116A114-A118 WeakPolarHBondContact O-CB 3.32Å; A114-A118 PolarHBondContact O-N 2.97Å; L115-A118 PolarHBondContact O-N 3Å; Y116-A118 VanDerWaalsContact C-N 3.27Å; Y116-A118 PolarHBondContact O-N 2.94Å
119R97.1Very high96.1Very high16 Ų1648.3 Ų48.36%0.0628%0.28CS..Hα-helixtrans-75.8-38.6177.7-70173.7162.8163.8-10.2112.2L115 Y116 E274 L277 R280L115-R119 HydrophobicContact CD1-CG 4.45Å; L115-R119 VanDerWaalsContact O-CG 3.23Å; L115-R119 WeakPolarHBondContact O-CG 3.24Å; L115-R119 PolarHBondContact O-N 3.19Å; L115-R119 VanDerWaalsContact O-N 3.13Å; Y116-R119 PolarHBondContact O-N 3.32Å; Y116-R119 VanDerWaalsContact O-N 3.09Å; R119-E274 IonicContact CZ-OE2 3.78Å; R119-E274 VanDerWaalsContact CZ-OE2 3.29Å; R119-E274 IonicContact NE-OE2 3.12Å; R119-E274 PolarHBondContact NE-OE2 3.06Å; R119-E274 VanDerWaalsContact NE-OE2 3.08Å; R119-E274 IonicContact NH2-OE2 3.51Å; R119-E274 PolarHBondContact NH2-OE2 3.28Å; R119-L277 HydrophobicContact CB-CD1 4.14Å; R119-L277 HydrophobicContact CG-CD1 3.62Å; R119-R280 PolarHBondContact O-NH1 3.04Å; R119-R280 PolarHBondContact O-NH2 3.3Å
120F96.9Very high95.8Very high1 Ų149 Ų490%0.00428%0.278CS..  trans-127.465.4-176.2-51.4-67000112.3R98 Y99 Y116 Q117 E122 H123 L273 L310R98-F120 HydrophobicContact CG-CD1 4.38Å; R98-F120 HydrophobicContact CG-CE1 4.02Å; R98-F120 HydrophobicContact CG-CZ 4.11Å; Y99-F120 HydrophobicContact CD2-CE2 4.2Å; Y99-F120 AromaticContact CD2-CZ 3.65Å; Y99-F120 HydrophobicContact CD2-CZ 3.65Å; Y99-F120 HydrophobicContact CE2-CZ 4.38Å; Y99-F120 HydrophobicContact CG-CE2 4.4Å; Y99-F120 HydrophobicContact CG-CZ 4.27Å; Y116-F120 HydrophobicContact CD1-CD2 4.37Å; Y116-F120 HydrophobicContact CD2-CD2 4Å; Y116-F120 HydrophobicContact CD2-CE2 4.35Å; Y116-F120 HydrophobicContact CE1-CB 4.18Å; Y116-F120 HydrophobicContact CE1-CD2 4.06Å; Y116-F120 AromaticContact CE2-CD2 3.67Å; Y116-F120 HydrophobicContact CE2-CD2 3.67Å; Y116-F120 HydrophobicContact CE2-CE2 4.03Å; Y116-F120 HydrophobicContact CG-CD2 4.32Å; Y116-F120 AromaticContact CZ-CD2 3.68Å; Y116-F120 PolarHBondContact O-N 3.08Å; Q117-F120 CarbonylContact O-C 3.56Å; F120-E122 VanDerWaalsContact CA-OE2 3.24Å; F120-E122 WeakPolarHBondContact CA-OE2 3.37Å; F120-E122 PolarHBondContact O-N 3.27Å; F120-E122 VanDerWaalsContact O-N 3.09Å; F120-H123 PolarHBondContact O-N 3.07Å; F120-L273 HydrophobicContact CE2-CD2 4.45Å; F120-L273 HydrophobicContact CZ-CD1 4.16Å; F120-L273 HydrophobicContact CZ-CD2 4.11Å; F120-L310 HydrophobicContact CE1-CD2 4.42Å
121P96.1Very high95.6Very high87 Ų8748.9 Ų48.957%0.56528%0.277SS*.THydrogen-bonded Turntrans-66.1-9.2-177.629.7-37.3000114.1Q117 H123Q117-P121 VanDerWaalsContact O-CA 3.28Å; Q117-P121 WeakPolarHBondContact O-CA 3.45Å; Q117-P121 VanDerWaalsContact O-N 3.16Å; P121-H123 VanDerWaalsContact C-N 3.31Å
122E94.9Very high95.4Very high21 Ų2151.2 Ų51.210%0.09829%0.285CS..THydrogen-bonded Turntrans-73.6-17.3173.265.7-95-132.100114.4P93 K94 F120 P303P93-E122 HydrophobicContact CB-CG 4.34Å; K94-E122 HydrophobicContact CG-CB 4.39Å; K94-E122 WeakPolarHBondContact CG-O 3.47Å; F120-E122 VanDerWaalsContact CA-OE2 3.24Å; F120-E122 WeakPolarHBondContact CA-OE2 3.37Å; F120-E122 PolarHBondContact O-N 3.27Å; F120-E122 VanDerWaalsContact O-N 3.09Å; E122-P303 HydrophobicContact CB-CB 4.07Å; E122-P303 HydrophobicContact CB-CG 4.33Å
123H96.3Very high95.3Very high4 Ų450.8 Ų50.82%0.01928%0.283CS..SBendtrans-88.2135.1178.2-63154.8000111.5P93 K94 T96 Y116 Q117 F120 P121P93-H123 PolarHBondContact O-NE2 2.92Å; K94-H123 PolarHBondContact O-CD2 2.92Å; T96-H123 PolarHBondContact O-NE2 3.35Å; Y116-H123 HydrophobicContact CE1-CB 4.48Å; Y116-H123 AromaticContact CE1-ND1 3.61Å; Y116-H123 AromaticContact CZ-ND1 3.71Å; Y116-H123 PolarHBondContact OH-CE1 3.35Å; Y116-H123 PolarHBondContact OH-ND1 2.92Å; Q117-H123 PolarHBondContact NE2-O 3.12Å; F120-H123 PolarHBondContact O-N 3.07Å; P121-H123 VanDerWaalsContact C-N 3.31Å
124E95.8Very high95.2Very high122 Ų12250.5 Ų50.557%0.5728%0.281SS*.EExtended strand (participates in β ladder)trans-94.4123.8173.7-174.5176.4154.400109.1Q137E124-Q137 HydrophobicContact CB-CB 4.06Å; E124-Q137 HydrophobicContact CG-CB 3.91Å; E124-Q137 PolarHBondContact O-N 3.06Å
125L97Very high95.2Very high24 Ų2448.4 Ų48.413%0.12626%0.259CS..EExtended strand (participates in β ladder)trans-109.4130.6-179.1-60.4-174.2000111.1V113 Y116 Q117 V134 H135 F136V113-L125 HydrophobicContact CG1-CD1 4.12Å; Y116-L125 HydrophobicContact CD1-CD1 4.32Å; Q117-L125 VanDerWaalsContact OE1-CG 3.3Å; L125-V134 HydrophobicContact CB-CG1 4.25Å; L125-V134 HydrophobicContact CD1-CG1 3.99Å; L125-V134 HydrophobicContact CD2-CG1 3.71Å; L125-V134 HydrophobicContact CG-CG1 4.2Å; L125-H135 WeakPolarHBondContact CA-O 3.32Å; L125-F136 HydrophobicContact CD2-CD1 3.45Å; L125-F136 VanDerWaalsContact CD2-CD1 3.45Å; L125-F136 HydrophobicContact CD2-CE1 3.7Å; L125-F136 HydrophobicContact CD2-CG 4.29Å
126T96.2Very high95.1Very high40 Ų4045.8 Ų45.825%0.24525%0.246CC..EExtended strand (participates in β ladder)trans-118178169.152.60000109.4H135 Q137T126-H135 PolarHBondContact N-O 3.08Å; T126-H135 PolarHBondContact O-N 2.92Å; T126-Q137 HydrophobicContact CG2-CB 4.24Å; T126-Q137 HydrophobicContact CG2-CG 4.4Å; T126-Q137 PolarHBondContact OG1-OE1 2.69Å
127F95.7Very high95Very high84 Ų8447.6 Ų47.637%0.36825%0.254SS..EExtended strand (participates in β ladder)trans-135.9140.6-173.9-54.8-74.6000111.7A108 V113 T133 V134A108-F127 HydrophobicContact CB-CD1 3.43Å; A108-F127 VanDerWaalsContact CB-CD1 3.43Å; A108-F127 HydrophobicContact CB-CD2 4.19Å; A108-F127 HydrophobicContact CB-CE1 3.44Å; A108-F127 VanDerWaalsContact CB-CE1 3.44Å; A108-F127 HydrophobicContact CB-CE2 4.2Å; A108-F127 HydrophobicContact CB-CG 3.83Å; A108-F127 HydrophobicContact CB-CZ 3.84Å; V113-F127 HydrophobicContact CG1-CE1 4.21Å; F127-T133 CarbonylContact C-O 3.47Å; F127-T133 WeakPolarHBondContact CA-O 3.35Å; F127-V134 HydrophobicContact CD1-CG2 4.49Å; F127-V134 HydrophobicContact CE1-CG2 4.16Å
128D93.1Very high94.7Very high35 Ų3546.1 Ų46.119%0.18725%0.248CC..  trans-64.2129.2174.1-179.1-91000110.7Q130 R131 Q132 T133 H135D128-Q130 PolarHBondContact O-N 3.11Å; D128-Q130 VanDerWaalsContact O-N 3.16Å; D128-Q130 WeakPolarHBondContact OD1-CA 3.44Å; D128-Q130 PolarHBondContact OD1-N 3.33Å; D128-R131 HydrophobicContact CB-CB 4.29Å; D128-R131 PolarHBondContact OD1-N 3.39Å; D128-Q132 WeakPolarHBondContact O-CA 3.45Å; D128-Q132 PolarHBondContact O-N 2.87Å; D128-Q132 PolarHBondContact O-NE2 2.93Å; D128-T133 PolarHBondContact N-O 2.73Å; D128-H135 IonicContact OD2-CE1 3.81Å
129P88.6Confident94.3Very high107 Ų10744.8 Ų44.870%0.69523%0.234SC*.THydrogen-bonded Turntrans-66.1-20.2-173.325.7-35.4000114.4Q132P129-Q132 PolarHBondContact O-NE2 3.18Å; P129-Q132 VanDerWaalsContact O-NE2 3.12Å
130Q87.9Confident93.7Very high151 Ų15149.8 Ų49.871%0.70627%0.271SS*.THydrogen-bonded Turntrans-102-48.1-178.7-62.2-176-0.900112.3D128D128-Q130 PolarHBondContact O-N 3.11Å; D128-Q130 VanDerWaalsContact O-N 3.16Å; D128-Q130 WeakPolarHBondContact OD1-CA 3.44Å; D128-Q130 PolarHBondContact OD1-N 3.33Å
131R91Very high93.1Very high11 Ų1158.1 Ų58.14%0.04231%0.311CS..THydrogen-bonded Turntrans-83-19.1-178.5-62.2178.674.2-134.816113Q107 D128 T133 E147 L646 P647Q107-R131 PolarHBondContact NE2-O 3.12Å; D128-R131 HydrophobicContact CB-CB 4.29Å; D128-R131 PolarHBondContact OD1-N 3.39Å; R131-T133 HydrophobicContact CB-CG2 3.96Å; R131-T133 WeakPolarHBondContact CB-OG1 3.48Å; R131-T133 PolarHBondContact NH1-OG1 3.44Å; R131-T133 VanDerWaalsContact NH1-OG1 3.11Å; R131-T133 PolarHBondContact O-N 3.11Å; R131-T133 VanDerWaalsContact O-N 3.15Å; R131-E147 IonicContact CZ-OE1 2.68Å; R131-E147 IonicContact NH1-OE1 2.67Å; R131-E147 PolarHBondContact NH1-OE1 3.11Å; R131-E147 IonicContact NH2-OE1 2.65Å; R131-E147 PolarHBondContact NH2-OE1 2.83Å; R131-E147 VanDerWaalsContact NH2-OE1 3.12Å; R131-L646 HydrophobicContact CB-CD1 4.44Å; R131-P647 PolarHBondContact NE-O 3.15Å
132Q93.4Very high92.7Very high89 Ų8956.2 Ų56.242%0.41630%0.295SS..  trans56.419.5-169.9-59.9-64.9-55.100113.7Q107 A108 D128 P129Q107-Q132 CarbonylContact C-O 3.53Å; Q107-Q132 VanDerWaalsContact CA-O 3.26Å; Q107-Q132 WeakPolarHBondContact CA-O 3.47Å; A108-Q132 PolarHBondContact N-O 3.28Å; D128-Q132 WeakPolarHBondContact O-CA 3.45Å; D128-Q132 PolarHBondContact O-N 2.87Å; D128-Q132 PolarHBondContact O-NE2 2.93Å; P129-Q132 PolarHBondContact O-NE2 3.18Å; P129-Q132 VanDerWaalsContact O-NE2 3.12Å
133T94.8Very high92.7Very high2 Ų259.4 Ų59.41%0.01231%0.31CS..BIsolated β-bridgetrans-80.7149.617847.40000112K106 F127 D128 R131 L646K106-T133 WeakPolarHBondContact O-CA 3.07Å; F127-T133 CarbonylContact C-O 3.47Å; F127-T133 WeakPolarHBondContact CA-O 3.35Å; D128-T133 PolarHBondContact N-O 2.73Å; R131-T133 HydrophobicContact CB-CG2 3.96Å; R131-T133 WeakPolarHBondContact CB-OG1 3.48Å; R131-T133 PolarHBondContact NH1-OG1 3.44Å; R131-T133 VanDerWaalsContact NH1-OG1 3.11Å; R131-T133 PolarHBondContact O-N 3.11Å; R131-T133 VanDerWaalsContact O-N 3.15Å; T133-L646 HydrophobicContact CG2-CD1 3.61Å; T133-L646 HydrophobicContact CG2-CD2 3.98Å; T133-L646 HydrophobicContact CG2-CG 4.41Å
134V96.3Very high92.6Very high1 Ų159.5 Ų59.51%0.00631%0.311CS..EExtended strand (participates in β ladder)trans-59.7138.2179.4-1710000112.2L103 V113 L125 F127 P146L103-V134 HydrophobicContact CD1-CG1 4.16Å; L103-V134 HydrophobicContact CD2-CG2 4.48Å; V113-V134 HydrophobicContact CB-CG2 4.42Å; V113-V134 HydrophobicContact CG1-CG2 3.85Å; V113-V134 HydrophobicContact CG2-CG2 3.65Å; L125-V134 HydrophobicContact CB-CG1 4.25Å; L125-V134 HydrophobicContact CD1-CG1 3.99Å; L125-V134 HydrophobicContact CD2-CG1 3.71Å; L125-V134 HydrophobicContact CG-CG1 4.2Å; F127-V134 HydrophobicContact CD1-CG2 4.49Å; F127-V134 HydrophobicContact CE1-CG2 4.16Å; V134-P146 HydrophobicContact CB-CG 4.38Å; V134-P146 WeakPolarHBondContact O-CD 3.24Å
135H96.6Very high92.7Very high24 Ų2453.9 Ų53.911%0.11129%0.285CS..EExtended strand (participates in β ladder)trans-120.7144.7159.1-69.4167.9000109.8L125 T126 D128 Q143 F144L125-H135 WeakPolarHBondContact CA-O 3.32Å; T126-H135 PolarHBondContact N-O 3.08Å; T126-H135 PolarHBondContact O-N 2.92Å; D128-H135 IonicContact OD2-CE1 3.81Å; H135-Q143 HydrophobicContact CB-CB 4.4Å; H135-Q143 PolarHBondContact ND1-OE1 2.75Å; H135-F144 CarbonylContact C-O 3.54Å; H135-F144 WeakPolarHBondContact CA-O 3.24Å
136F96.9Very high92.8Very high1 Ų152.8 Ų52.80%0.00428%0.279CS..EExtended strand (participates in β ladder)trans-86.3123.3167.6-63-78.6000109.8L97 F100 L103 Y116 L125 I138 Q143 F144 P146 V149L97-F136 HydrophobicContact CD1-CB 3.99Å; L97-F136 HydrophobicContact CD1-CD1 4.3Å; L97-F136 HydrophobicContact CD1-CD2 3.69Å; L97-F136 HydrophobicContact CD1-CE2 4.2Å; L97-F136 HydrophobicContact CD1-CG 3.74Å; L97-F136 HydrophobicContact CD2-CB 4.12Å; L97-F136 HydrophobicContact CD2-CD1 3.51Å; L97-F136 HydrophobicContact CD2-CD2 4.42Å; L97-F136 HydrophobicContact CD2-CE1 3.93Å; L97-F136 HydrophobicContact CD2-CG 3.77Å; L97-F136 HydrophobicContact CG-CG 4.4Å; F100-F136 HydrophobicContact CB-CE2 3.75Å; F100-F136 HydrophobicContact CB-CZ 3.51Å; L103-F136 HydrophobicContact CD1-CE1 4.14Å; L103-F136 HydrophobicContact CD1-CZ 3.7Å; Y116-F136 AromaticContact CE1-CE1 3.76Å; Y116-F136 HydrophobicContact CE1-CE1 3.76Å; Y116-F136 HydrophobicContact CE1-CZ 4.41Å; Y116-F136 AromaticContact CZ-CE1 3.83Å; L125-F136 HydrophobicContact CD2-CD1 3.45Å; L125-F136 VanDerWaalsContact CD2-CD1 3.45Å; L125-F136 HydrophobicContact CD2-CE1 3.7Å; L125-F136 HydrophobicContact CD2-CG 4.29Å; F136-I138 HydrophobicContact CB-CD1 4.29Å; F136-Q143 CarbonylContact O-C 3.52Å; F136-Q143 VanDerWaalsContact O-CA 3.22Å; F136-Q143 WeakPolarHBondContact O-CA 3.32Å; F136-F144 PolarHBondContact N-O 3.47Å; F136-F144 PolarHBondContact O-N 2.92Å; F136-P146 HydrophobicContact CE2-CG 4.08Å; F136-V149 HydrophobicContact CD2-CG2 4.17Å; F136-V149 HydrophobicContact CE2-CG2 4.46Å
137Q95.2Very high92.8Very high41 Ų4151 Ų5119%0.19227%0.268CS..EExtended strand (participates in β ladder)trans-88.6112.1174.1-157.970.245.600109.4E124 T126 S139E124-Q137 HydrophobicContact CB-CB 4.06Å; E124-Q137 HydrophobicContact CG-CB 3.91Å; E124-Q137 PolarHBondContact O-N 3.06Å; T126-Q137 HydrophobicContact CG2-CB 4.24Å; T126-Q137 HydrophobicContact CG2-CG 4.4Å; T126-Q137 PolarHBondContact OG1-OE1 2.69Å; Q137-S139 PolarHBondContact NE2-O 3.09Å
138I92.4Very high92.9Very high34 Ų3447.3 Ų47.317%0.17425%0.252CS..EExtended strand (participates in β ladder)trans-100.3-35.6-177-55.9-60.4000111.1L74 A95 L97 F136 L142 F144L74-I138 HydrophobicContact CB-CG2 3.95Å; L74-I138 HydrophobicContact CD1-CD1 4.1Å; L74-I138 HydrophobicContact CD1-CG1 3.89Å; A95-I138 HydrophobicContact CB-CG2 4.22Å; L97-I138 HydrophobicContact CD1-CD1 4.27Å; L97-I138 HydrophobicContact CD2-CD1 4.15Å; L97-I138 HydrophobicContact CG-CD1 4.36Å; F136-I138 HydrophobicContact CB-CD1 4.29Å; I138-L142 HydrophobicContact CB-CB 4.16Å; I138-L142 PolarHBondContact N-O 3.12Å; I138-F144 HydrophobicContact CG1-CD2 3.87Å; I138-F144 HydrophobicContact CG1-CE2 4.28Å
139S87.6Confident93.2Very high46 Ų4645.7 Ų45.732%0.32224%0.243SC..EExtended strand (participates in β ladder)trans-152.4175.5170.180.20000109.5Q137 Q141 L142Q137-S139 PolarHBondContact NE2-O 3.09Å; S139-Q141 PolarHBondContact O-N 3.33Å; S139-Q141 PolarHBondContact OG-N 3.32Å; S139-L142 PolarHBondContact N-O 2.96Å; S139-L142 VanDerWaalsContact N-O 3.17Å; S139-L142 PolarHBondContact O-N 3.16Å; S139-L142 WeakPolarHBondContact OG-CB 3.45Å; S139-L142 PolarHBondContact OG-N 3.25Å; S139-L142 VanDerWaalsContact OG-N 3.16Å
140S84.6Confident93.7Very high120 Ų12040.6 Ų40.684%0.83921%0.21SC*.THydrogen-bonded Turntrans-60.8-12174.654.60000114.7
141Q84.1Confident94.2Very high177 Ų17733.4 Ų33.483%0.82718%0.176SC*.THydrogen-bonded Turntrans-117-13.5178.7-63.7176.1-5.900113S139S139-Q141 PolarHBondContact O-N 3.33Å; S139-Q141 PolarHBondContact OG-N 3.32Å
142L88.6Confident94.5Very high47 Ų4732.9 Ų32.925%0.24618%0.175CC..EExtended strand (participates in β ladder)trans-121111.3-173.3-62.9176.1000110.9N77 I138 S139 F144N77-L142 WeakPolarHBondContact OD1-CD1 3.4Å; I138-L142 HydrophobicContact CB-CB 4.16Å; I138-L142 PolarHBondContact N-O 3.12Å; S139-L142 PolarHBondContact N-O 2.96Å; S139-L142 VanDerWaalsContact N-O 3.17Å; S139-L142 PolarHBondContact O-N 3.16Å; S139-L142 WeakPolarHBondContact OG-CB 3.45Å; S139-L142 PolarHBondContact OG-N 3.25Å; S139-L142 VanDerWaalsContact OG-N 3.16Å; L142-F144 HydrophobicContact CB-CE2 4.11Å
143Q93.8Very high94.8Very high88 Ų8828.8 Ų28.841%0.41116%0.156SC..EExtended strand (participates in β ladder)trans-119.6147.7166.860.6178.4-28.700109.4H135 F136 K660H135-Q143 HydrophobicContact CB-CB 4.4Å; H135-Q143 PolarHBondContact ND1-OE1 2.75Å; F136-Q143 CarbonylContact O-C 3.52Å; F136-Q143 VanDerWaalsContact O-CA 3.22Å; F136-Q143 WeakPolarHBondContact O-CA 3.32Å; Q143-K660 PolarHBondContact O-NZ 2.79Å
144F95.9Very high94.9Very high5 Ų528.7 Ų28.72%0.02216%0.155CC..EExtended strand (participates in β ladder)trans-138.7138.4175.2-64.4-90000112.9L74 H135 F136 I138 L142 E148 V149 M152 K660 L661 L664L74-F144 HydrophobicContact CD1-CD2 3.71Å; L74-F144 HydrophobicContact CD1-CE2 3.75Å; L74-F144 HydrophobicContact CD1-CG 4.39Å; L74-F144 HydrophobicContact CD1-CZ 4.45Å; H135-F144 CarbonylContact C-O 3.54Å; H135-F144 WeakPolarHBondContact CA-O 3.24Å; F136-F144 PolarHBondContact N-O 3.47Å; F136-F144 PolarHBondContact O-N 2.92Å; I138-F144 HydrophobicContact CG1-CD2 3.87Å; I138-F144 HydrophobicContact CG1-CE2 4.28Å; L142-F144 HydrophobicContact CB-CE2 4.11Å; F144-E148 WeakPolarHBondContact CA-OE2 3.24Å; F144-E148 HydrophobicContact CD1-CB 4.45Å; F144-V149 HydrophobicContact CB-CG2 3.87Å; F144-M152 HydrophobicContact CD1-CE 3.25Å; F144-M152 HydrophobicContact CE1-CE 3.22Å; F144-M152 HydrophobicContact CG-CE 3.97Å; F144-M152 HydrophobicContact CZ-CE 3.94Å; F144-K660 HydrophobicContact CE1-CD 4.44Å; F144-L661 HydrophobicContact CE1-CD2 4.45Å; F144-L664 HydrophobicContact CE1-CD1 3.87Å; F144-L664 HydrophobicContact CZ-CD1 3.97Å
145S97.2Very high95Very high4 Ų429.7 Ų29.73%0.02816%0.161CC..  trans-80.4157173.494.90000112E147 E148 V149S145-E147 WeakPolarHBondContact CB-OE2 3.46Å; S145-E147 PolarHBondContact O-N 2.85Å; S145-E147 PolarHBondContact OG-N 2.82Å; S145-E147 PolarHBondContact OG-OE2 3.39Å; S145-E148 PolarHBondContact N-OE2 2.98Å; S145-E148 VanDerWaalsContact N-OE2 3.1Å; S145-E148 PolarHBondContact O-N 2.97Å; S145-E148 PolarHBondContact OG-N 3.25Å; S145-E148 VanDerWaalsContact OG-N 3.15Å; S145-V149 WeakPolarHBondContact O-CG2 3.44Å; S145-V149 PolarHBondContact O-N 3.33Å
146P97.9Very high95.1Very high1 Ų129.5 Ų29.51%0.00616%0.159CC..Hα-helixtrans-53.1-35.5170.8-27.734.8000113.5L103 L104 V134 F136 L150L103-P146 HydrophobicContact CB-CB 4.22Å; L103-P146 HydrophobicContact CB-CG 3.69Å; L104-P146 HydrophobicContact CD2-CB 4.01Å; L104-P146 HydrophobicContact CG-CB 4.46Å; V134-P146 HydrophobicContact CB-CG 4.38Å; V134-P146 WeakPolarHBondContact O-CD 3.24Å; F136-P146 HydrophobicContact CE2-CG 4.08Å; P146-L150 WeakPolarHBondContact O-CB 3.31Å; P146-L150 PolarHBondContact O-N 2.83Å
147E98Very high95.1Very high2 Ų229.5 Ų29.51%0.00916%0.159CC..Hα-helixtrans-67.7-40.8174.7-51.495.7142.800112L104 R131 S145 L150 G151 A187 A191 M194L104-E147 HydrophobicContact CD2-CG 4.23Å; R131-E147 IonicContact CZ-OE1 2.68Å; R131-E147 IonicContact NH1-OE1 2.67Å; R131-E147 PolarHBondContact NH1-OE1 3.11Å; R131-E147 IonicContact NH2-OE1 2.65Å; R131-E147 PolarHBondContact NH2-OE1 2.83Å; R131-E147 VanDerWaalsContact NH2-OE1 3.12Å; S145-E147 WeakPolarHBondContact CB-OE2 3.46Å; S145-E147 PolarHBondContact O-N 2.85Å; S145-E147 PolarHBondContact OG-N 2.82Å; S145-E147 PolarHBondContact OG-OE2 3.39Å; E147-L150 PolarHBondContact O-N 2.96Å; E147-G151 PolarHBondContact O-N 3.36Å; E147-A187 HydrophobicContact CG-CB 3.85Å; E147-A191 HydrophobicContact CB-CB 4.48Å; E147-A191 WeakPolarHBondContact O-CB 3.46Å; E147-M194 HydrophobicContact CB-CE 4.4Å
148E98Very high95.2Very high8 Ų829.8 Ų29.84%0.03716%0.158CC..Hα-helixtrans-65.6-42.7174.2-70.6-176.4138.200112.3F144 S145 L150 G151 M152 M194 S657 K660 L661F144-E148 WeakPolarHBondContact CA-OE2 3.24Å; F144-E148 HydrophobicContact CD1-CB 4.45Å; S145-E148 PolarHBondContact N-OE2 2.98Å; S145-E148 VanDerWaalsContact N-OE2 3.1Å; S145-E148 PolarHBondContact O-N 2.97Å; S145-E148 PolarHBondContact OG-N 3.25Å; S145-E148 VanDerWaalsContact OG-N 3.15Å; E148-L150 VanDerWaalsContact C-N 3.35Å; E148-G151 WeakPolarHBondContact O-CA 3.21Å; E148-G151 PolarHBondContact O-N 3.21Å; E148-G151 VanDerWaalsContact O-N 3.1Å; E148-M152 WeakPolarHBondContact O-CG 3.13Å; E148-M152 PolarHBondContact O-N 3.23Å; E148-M194 HydrophobicContact CB-SD 4.41Å; E148-M194 HydrophobicContact CG-CE 4.25Å; E148-M194 HydrophobicContact CG-SD 3.86Å; E148-S657 VanDerWaalsContact OE1-CB 3.23Å; E148-S657 WeakPolarHBondContact OE1-CB 3.5Å; E148-S657 PolarHBondContact OE1-OG 3.36Å; E148-K660 WeakPolarHBondContact OE1-CD 3.46Å; E148-K660 IonicContact OE1-NZ 2.78Å; E148-K660 PolarHBondContact OE1-NZ 3.39Å; E148-K660 IonicContact OE2-NZ 3.47Å; E148-K660 PolarHBondContact OE2-NZ 3.41Å; E148-L661 WeakPolarHBondContact O-CD1 3.47Å
149V98.3Very high95.4Very high0 Ų029.7 Ų29.70%016%0.161CC..Hα-helixtrans-64.9-40.7177.8179.80000110.5V72 L97 F100 F136 F144 S145 G151 M152 V153V72-V149 HydrophobicContact CB-CG1 4.28Å; V72-V149 HydrophobicContact CG2-CG1 3.92Å; L97-V149 HydrophobicContact CB-CG1 4.4Å; L97-V149 HydrophobicContact CD1-CB 4.49Å; L97-V149 HydrophobicContact CD1-CG1 4.08Å; L97-V149 HydrophobicContact CD1-CG2 3.56Å; F100-V149 HydrophobicContact CD1-CG1 3.83Å; F100-V149 HydrophobicContact CD2-CB 4.23Å; F100-V149 HydrophobicContact CD2-CG1 4.01Å; F100-V149 HydrophobicContact CE1-CG1 3.71Å; F100-V149 HydrophobicContact CE2-CB 4.27Å; F100-V149 HydrophobicContact CE2-CG1 3.9Å; F100-V149 HydrophobicContact CG-CG1 4Å; F100-V149 HydrophobicContact CZ-CG1 3.76Å; F136-V149 HydrophobicContact CD2-CG2 4.17Å; F136-V149 HydrophobicContact CE2-CG2 4.46Å; F144-V149 HydrophobicContact CB-CG2 3.87Å; S145-V149 WeakPolarHBondContact O-CG2 3.44Å; S145-V149 PolarHBondContact O-N 3.33Å; V149-G151 VanDerWaalsContact C-N 3.32Å; V149-G151 PolarHBondContact O-N 3.13Å; V149-M152 WeakPolarHBondContact O-CB 3.37Å; V149-M152 PolarHBondContact O-N 2.8Å; V149-V153 PolarHBondContact O-N 3.33Å; V149-V153 VanDerWaalsContact O-N 3.16Å
150L98.6Very high95.8Very high0 Ų027.9 Ų27.90%015%0.147CC..Hα-helixtrans-62.4-39.6170.3-179.357000111.5L40 F100 L104 P146 E147 E148 M152 V153 L154 V188 A191L40-L150 HydrophobicContact CD1-CD1 3.73Å; L40-L150 HydrophobicContact CD2-CD1 3.77Å; L40-L150 HydrophobicContact CD2-CD2 4.23Å; L40-L150 HydrophobicContact CG-CD1 4.34Å; F100-L150 HydrophobicContact CE2-CB 3.97Å; L104-L150 HydrophobicContact CD1-CD2 3.89Å; L104-L150 HydrophobicContact CD2-CB 4.37Å; L104-L150 HydrophobicContact CD2-CD2 3.97Å; P146-L150 WeakPolarHBondContact O-CB 3.31Å; P146-L150 PolarHBondContact O-N 2.83Å; E147-L150 PolarHBondContact O-N 2.96Å; E148-L150 VanDerWaalsContact C-N 3.35Å; L150-M152 VanDerWaalsContact C-N 3.29Å; L150-M152 PolarHBondContact O-N 3.15Å; L150-V153 PolarHBondContact O-N 2.95Å; L150-V153 VanDerWaalsContact O-N 3.12Å; L150-L154 HydrophobicContact CD1-CD1 4.22Å; L150-L154 HydrophobicContact CD1-CG 3.99Å; L150-L154 HydrophobicContact CD2-CD1 4.48Å; L150-L154 HydrophobicContact CG-CD1 3.93Å; L150-L154 HydrophobicContact CG-CG 4.18Å; L150-L154 WeakPolarHBondContact O-CB 3.35Å; L150-L154 WeakPolarHBondContact O-CG 3.35Å; L150-L154 PolarHBondContact O-N 3.29Å; L150-V188 HydrophobicContact CD2-CB 4.45Å; L150-V188 HydrophobicContact CD2-CG1 4.39Å; L150-V188 HydrophobicContact CD2-CG2 4.12Å; L150-A191 HydrophobicContact CB-CB 3.69Å; L150-A191 HydrophobicContact CD2-CB 3.6Å; L150-A191 HydrophobicContact CG-CB 3.55Å
151G98.4Very high96.4Very high0 Ų022.1 Ų22.10%011%0.107CC..Hα-helixtrans-59.6-37174.900000113E147 E148 V149 N155 A191E147-G151 PolarHBondContact O-N 3.36Å; E148-G151 WeakPolarHBondContact O-CA 3.21Å; E148-G151 PolarHBondContact O-N 3.21Å; E148-G151 VanDerWaalsContact O-N 3.1Å; V149-G151 VanDerWaalsContact C-N 3.32Å; V149-G151 PolarHBondContact O-N 3.13Å; G151-N155 VanDerWaalsContact O-CB 3.29Å; G151-N155 WeakPolarHBondContact O-CB 3.44Å; G151-N155 PolarHBondContact O-N 2.81Å; G151-A191 WeakPolarHBondContact CA-O 3.47Å
152M98.1Very high96.9Very high1 Ų116 Ų161%0.0058%0.079CC..Hα-helixtrans-64.4-45.7171.6-55.7-173.5-159.400112V72 L74 R79 F81 F144 E148 V149 L150 N155 Y156 L661 L664V72-M152 HydrophobicContact CG1-SD 4.11Å; L74-M152 HydrophobicContact CD1-CE 4.49Å; L74-M152 HydrophobicContact CD2-CE 4.29Å; L74-M152 HydrophobicContact CD2-SD 3.99Å; R79-M152 VanDerWaalsContact CD-SD 3.54Å; F81-M152 HydrophobicContact CE1-CB 3.72Å; F81-M152 HydrophobicContact CZ-CB 3.97Å; F144-M152 HydrophobicContact CD1-CE 3.25Å; F144-M152 HydrophobicContact CE1-CE 3.22Å; F144-M152 HydrophobicContact CG-CE 3.97Å; F144-M152 HydrophobicContact CZ-CE 3.94Å; E148-M152 WeakPolarHBondContact O-CG 3.13Å; E148-M152 PolarHBondContact O-N 3.23Å; V149-M152 WeakPolarHBondContact O-CB 3.37Å; V149-M152 PolarHBondContact O-N 2.8Å; L150-M152 VanDerWaalsContact C-N 3.29Å; L150-M152 PolarHBondContact O-N 3.15Å; M152-N155 PolarHBondContact O-N 3.05Å; M152-Y156 PolarHBondContact O-N 3.22Å; M152-L661 HydrophobicContact CE-CD2 3.66Å; M152-L661 HydrophobicContact CG-CD1 4.29Å; M152-L661 HydrophobicContact CG-CD2 3.77Å; M152-L661 HydrophobicContact SD-CD2 4.45Å; M152-L664 HydrophobicContact CE-CD1 4.4Å
153V98.5Very high97.1Very high3 Ų318.8 Ų18.82%0.0189%0.093CC..Hα-helixtrans-63.7-43.4178.9172.50000111.2M45 V70 V72 F100 V149 L150 Y156 S157M45-V153 HydrophobicContact CE-CG1 4.18Å; M45-V153 HydrophobicContact SD-CG1 3.44Å; M45-V153 WeakPolarHBondContact SD-CG1 3.47Å; V70-V153 HydrophobicContact CG1-CG1 4.18Å; V70-V153 HydrophobicContact CG1-CG2 4.33Å; V72-V153 HydrophobicContact CG2-CG2 3.45Å; V72-V153 VanDerWaalsContact CG2-CG2 3.45Å; F100-V153 HydrophobicContact CZ-CG2 3.99Å; V149-V153 PolarHBondContact O-N 3.33Å; V149-V153 VanDerWaalsContact O-N 3.16Å; L150-V153 PolarHBondContact O-N 2.95Å; L150-V153 VanDerWaalsContact O-N 3.12Å; V153-Y156 PolarHBondContact O-N 3.18Å; V153-S157 PolarHBondContact O-N 3.18Å; V153-S157 PolarHBondContact O-OG 3.46Å
154L98.6Very high97Very high0 Ų017.5 Ų17.50%09%0.087CC..Hα-helixtrans-67.3-36.4177-69.5176.5000112.5V38 L150 S157 R158 I174 A191 A192 A195 L197V38-L154 HydrophobicContact CG1-CD2 4.4Å; V38-L154 HydrophobicContact CG2-CD2 4.3Å; L150-L154 HydrophobicContact CD1-CD1 4.22Å; L150-L154 HydrophobicContact CD1-CG 3.99Å; L150-L154 HydrophobicContact CD2-CD1 4.48Å; L150-L154 HydrophobicContact CG-CD1 3.93Å; L150-L154 HydrophobicContact CG-CG 4.18Å; L150-L154 WeakPolarHBondContact O-CB 3.35Å; L150-L154 WeakPolarHBondContact O-CG 3.35Å; L150-L154 PolarHBondContact O-N 3.29Å; L154-S157 WeakPolarHBondContact O-CB 3.38Å; L154-S157 PolarHBondContact O-N 3.42Å; L154-R158 PolarHBondContact O-N 3.08Å; L154-I174 HydrophobicContact CD1-CD1 3.99Å; L154-I174 HydrophobicContact CD2-CD1 3.91Å; L154-A191 HydrophobicContact CD1-CB 4.18Å; L154-A192 HydrophobicContact CD1-CB 4.02Å; L154-A195 HydrophobicContact CB-CB 3.84Å; L154-L197 HydrophobicContact CB-CD1 4.19Å
155N97.8Very high96.8Very high22 Ų2217.4 Ų17.412%0.1189%0.087CC..Hα-helixtrans-64.6-39.8171.3177.471.8000111.7G151 M152 R158 S159 A195G151-N155 VanDerWaalsContact O-CB 3.29Å; G151-N155 WeakPolarHBondContact O-CB 3.44Å; G151-N155 PolarHBondContact O-N 2.81Å; M152-N155 PolarHBondContact O-N 3.05Å; N155-R158 WeakPolarHBondContact O-CB 3.44Å; N155-R158 PolarHBondContact O-N 2.85Å; N155-R158 PolarHBondContact OD1-NH2 2.87Å; N155-S159 PolarHBondContact O-N 3.16Å; N155-A195 HydrophobicContact CB-CB 4.16Å
156Y97.6Very high96.6Very high20 Ų2025.6 Ų25.68%0.07812%0.124CC..Hα-helixtrans-66.7-42.8174178.2-119.3000111.9M45 T68 F81 M152 V153 R158 S159 L160M45-Y156 HydrophobicContact CE-CD1 3.85Å; M45-Y156 HydrophobicContact CE-CE1 4.26Å; T68-Y156 HydrophobicContact CG2-CE1 3.86Å; F81-Y156 HydrophobicContact CB-CD1 3.42Å; F81-Y156 VanDerWaalsContact CB-CD1 3.42Å; F81-Y156 HydrophobicContact CB-CD2 4.15Å; F81-Y156 HydrophobicContact CB-CE1 3.43Å; F81-Y156 VanDerWaalsContact CB-CE1 3.43Å; F81-Y156 HydrophobicContact CB-CE2 4.17Å; F81-Y156 HydrophobicContact CB-CG 3.79Å; F81-Y156 HydrophobicContact CD1-CD1 4.26Å; F81-Y156 HydrophobicContact CD1-CG 4.22Å; F81-Y156 HydrophobicContact CD2-CD2 4.02Å; F81-Y156 HydrophobicContact CD2-CG 4.02Å; F81-Y156 AromaticContact CG-CD1 3.83Å; F81-Y156 HydrophobicContact CG-CD1 3.83Å; F81-Y156 HydrophobicContact CG-CD2 4.14Å; F81-Y156 HydrophobicContact CG-CE1 4.3Å; F81-Y156 AromaticContact CG-CG 3.73Å; F81-Y156 HydrophobicContact CG-CG 3.73Å; M152-Y156 PolarHBondContact O-N 3.22Å; V153-Y156 PolarHBondContact O-N 3.18Å; Y156-R158 VanDerWaalsContact C-N 3.27Å; Y156-R158 PolarHBondContact O-N 3.26Å; Y156-S159 WeakPolarHBondContact CA-OG 3.26Å; Y156-S159 PolarHBondContact O-N 3.34Å; Y156-S159 VanDerWaalsContact O-N 3.09Å; Y156-S159 PolarHBondContact O-OG 2.81Å; Y156-L160 HydrophobicContact CD1-CD1 4.38Å; Y156-L160 HydrophobicContact CE1-CD1 3.88Å; Y156-L160 HydrophobicContact CE1-CG 4.39Å; Y156-L160 HydrophobicContact CE2-CD2 4.08Å; Y156-L160 HydrophobicContact CE2-CG 4.16Å; Y156-L160 PolarHBondContact O-N 3.43Å
157S98.1Very high96.2Very high0 Ų028.1 Ų28.10%014%0.136CC..Hα-helixtrans-55.4-41.9171.3-58.80000112.1M36 M45 V153 L154 A161M36-S157 WeakPolarHBondContact CE-O 3.37Å; M45-S157 VanDerWaalsContact CE-OG 3.23Å; M45-S157 WeakPolarHBondContact CE-OG 3.41Å; M45-S157 PolarHBondContact SD-OG 3.39Å; V153-S157 PolarHBondContact O-N 3.18Å; V153-S157 PolarHBondContact O-OG 3.46Å; L154-S157 WeakPolarHBondContact O-CB 3.38Å; L154-S157 PolarHBondContact O-N 3.42Å; S157-A161 PolarHBondContact O-N 3.09Å
158R97.3Very high95.9Very high47 Ų4731.3 Ų31.318%0.17716%0.157CC..Hα-helixtrans-61.7-51173.4-173.8-172.755.5-153.4-11.4110.4M36 L154 N155 Y156 L160 A161 E162 I169 A195 G196 L197M36-R158 HydrophobicContact SD-CB 4.35Å; M36-R158 HydrophobicContact SD-CG 4.45Å; L154-R158 PolarHBondContact O-N 3.08Å; N155-R158 WeakPolarHBondContact O-CB 3.44Å; N155-R158 PolarHBondContact O-N 2.85Å; N155-R158 PolarHBondContact OD1-NH2 2.87Å; Y156-R158 VanDerWaalsContact C-N 3.27Å; Y156-R158 PolarHBondContact O-N 3.26Å; R158-L160 VanDerWaalsContact C-N 3.31Å; R158-L160 PolarHBondContact O-N 3.19Å; R158-A161 CarbonylContact O-C 3.5Å; R158-A161 WeakPolarHBondContact O-CA 3.36Å; R158-A161 WeakPolarHBondContact O-CB 3.24Å; R158-A161 PolarHBondContact O-N 3.27Å; R158-E162 WeakPolarHBondContact CD-OE1 3.28Å; R158-E162 VanDerWaalsContact CG-CD 3.48Å; R158-E162 HydrophobicContact CG-CG 3.87Å; R158-E162 WeakPolarHBondContact CG-OE2 3.37Å; R158-E162 IonicContact NE-OE1 2.68Å; R158-E162 IonicContact NE-OE2 3.57Å; R158-E162 PolarHBondContact NE-OE2 3.42Å; R158-E162 WeakPolarHBondContact O-CG 3.48Å; R158-E162 PolarHBondContact O-N 3.36Å; R158-I169 WeakPolarHBondContact CD-O 3.42Å; R158-I169 HydrophobicContact CG-CB 4.29Å; R158-A195 VanDerWaalsContact CZ-O 3.27Å; R158-A195 PolarHBondContact NH1-O 2.98Å; R158-A195 PolarHBondContact NH2-O 3.36Å; R158-A195 VanDerWaalsContact NH2-O 3.13Å; R158-G196 PolarHBondContact NH1-O 3.36Å; R158-L197 HydrophobicContact CB-CD2 4.21Å; R158-L197 HydrophobicContact CG-CD2 4.07Å
159S96.1Very high95.7Very high33 Ų3331 Ų3123%0.23116%0.156CC..Hα-helixtrans-58.4-39.7-178.362.90000113.4N155 Y156 A161 E162 D163N155-S159 PolarHBondContact O-N 3.16Å; Y156-S159 WeakPolarHBondContact CA-OG 3.26Å; Y156-S159 PolarHBondContact O-N 3.34Å; Y156-S159 VanDerWaalsContact O-N 3.09Å; Y156-S159 PolarHBondContact O-OG 2.81Å; S159-A161 VanDerWaalsContact C-N 3.33Å; S159-A161 PolarHBondContact O-N 2.68Å; S159-E162 PolarHBondContact O-N 3.34Å; S159-D163 WeakPolarHBondContact O-CB 3.49Å; S159-D163 VanDerWaalsContact O-CG 3.31Å; S159-D163 PolarHBondContact O-N 2.89Å
160L96.6Very high95.5Very high7 Ų736.3 Ų36.34%0.03718%0.179CC..Hα-helixtrans-60.9-41.9173.1-67.1179.4000112.1V59 N61 K62 Y156 R158 F164V59-L160 HydrophobicContact CG1-CB 3.99Å; V59-L160 VanDerWaalsContact CG1-O 3.31Å; V59-L160 WeakPolarHBondContact CG1-O 3.45Å; N61-L160 HydrophobicContact CB-CD1 4.11Å; K62-L160 HydrophobicContact CG-CD2 4.15Å; Y156-L160 HydrophobicContact CD1-CD1 4.38Å; Y156-L160 HydrophobicContact CE1-CD1 3.88Å; Y156-L160 HydrophobicContact CE1-CG 4.39Å; Y156-L160 HydrophobicContact CE2-CD2 4.08Å; Y156-L160 HydrophobicContact CE2-CG 4.16Å; Y156-L160 PolarHBondContact O-N 3.43Å; R158-L160 VanDerWaalsContact C-N 3.31Å; R158-L160 PolarHBondContact O-N 3.19Å; L160-F164 PolarHBondContact O-N 2.9Å
161A96.2Very high95.4Very high0 Ų037.6 Ų37.60%019%0.186CC..Hα-helixtrans-71.2-36.3177.200000112.4M36 V47 I49 V59 S157 R158 S159 F164 A165 I169M36-A161 HydrophobicContact CB-CB 4.3Å; M36-A161 HydrophobicContact CE-CB 3.92Å; M36-A161 HydrophobicContact SD-CB 4.32Å; V47-A161 HydrophobicContact CG1-CB 3.91Å; I49-A161 HydrophobicContact CD1-CB 4.47Å; V59-A161 HydrophobicContact CG2-CB 4.37Å; S157-A161 PolarHBondContact O-N 3.09Å; R158-A161 CarbonylContact O-C 3.5Å; R158-A161 WeakPolarHBondContact O-CA 3.36Å; R158-A161 WeakPolarHBondContact O-CB 3.24Å; R158-A161 PolarHBondContact O-N 3.27Å; S159-A161 VanDerWaalsContact C-N 3.33Å; S159-A161 PolarHBondContact O-N 2.68Å; A161-F164 PolarHBondContact O-N 2.8Å; A161-A165 WeakPolarHBondContact O-CB 3.28Å; A161-A165 PolarHBondContact O-N 2.7Å; A161-I169 HydrophobicContact CB-CD1 3.48Å; A161-I169 VanDerWaalsContact CB-CD1 3.48Å
162E95.1Very high95.4Very high49 Ų4937.6 Ų37.623%0.22919%0.186CC..Hα-helixtrans-67.3-42.6176.3-71.1177.9137.300111.5R158 S159 F164 A165 E166 P168 I169R158-E162 WeakPolarHBondContact CD-OE1 3.28Å; R158-E162 VanDerWaalsContact CG-CD 3.48Å; R158-E162 HydrophobicContact CG-CG 3.87Å; R158-E162 WeakPolarHBondContact CG-OE2 3.37Å; R158-E162 IonicContact NE-OE1 2.68Å; R158-E162 IonicContact NE-OE2 3.57Å; R158-E162 PolarHBondContact NE-OE2 3.42Å; R158-E162 WeakPolarHBondContact O-CG 3.48Å; R158-E162 PolarHBondContact O-N 3.36Å; S159-E162 PolarHBondContact O-N 3.34Å; E162-F164 VanDerWaalsContact C-N 3.33Å; E162-F164 PolarHBondContact O-N 3.37Å; E162-A165 PolarHBondContact O-N 2.69Å; E162-A165 VanDerWaalsContact O-N 3.16Å; E162-E166 PolarHBondContact O-N 3.34Å; E162-P168 VanDerWaalsContact OE1-CA 3.25Å; E162-P168 WeakPolarHBondContact OE1-CA 3.45Å; E162-I169 HydrophobicContact CG-CB 3.97Å; E162-I169 HydrophobicContact CG-CD1 4.25Å; E162-I169 HydrophobicContact CG-CG1 3.97Å; E162-I169 PolarHBondContact OE1-N 3.32Å
163D93.4Very high95.4Very high104 Ų10437.5 Ų37.556%0.55619%0.185SC*.Hα-helixtrans-57.5-43.9172.6-76.7-20.3000110.9S159S159-D163 WeakPolarHBondContact O-CB 3.49Å; S159-D163 VanDerWaalsContact O-CG 3.31Å; S159-D163 PolarHBondContact O-N 2.89Å
164F91.9Very high95.4Very high62 Ų6237.4 Ų37.427%0.27219%0.185SC..Hα-helixtrans-73.5-30.5175.4-172.5-81.3000113I49 K51 E57 V59 L160 A161 E162I49-F164 HydrophobicContact CD1-CD1 4.37Å; I49-F164 HydrophobicContact CG2-CD1 3.6Å; I49-F164 HydrophobicContact CG2-CE1 3.61Å; K51-F164 PolarHBondContact NZ-O 3.47Å; E57-F164 HydrophobicContact CG-CZ 4.32Å; V59-F164 HydrophobicContact CG1-CB 4.07Å; V59-F164 HydrophobicContact CG1-CG 4.5Å; V59-F164 HydrophobicContact CG2-CB 4.27Å; V59-F164 HydrophobicContact CG2-CD1 4.38Å; V59-F164 HydrophobicContact CG2-CG 4.21Å; L160-F164 PolarHBondContact O-N 2.9Å; A161-F164 PolarHBondContact O-N 2.8Å; E162-F164 VanDerWaalsContact C-N 3.33Å; E162-F164 PolarHBondContact O-N 3.37Å
165A91.9Very high95.4Very high2 Ų237.6 Ų37.62%0.01719%0.186CC..Hα-helixtrans-79.9-26.7-176.700000113.6A34 I49 K51 A161 E162 Q167 I169A34-A165 HydrophobicContact CB-CB 4.27Å; I49-A165 HydrophobicContact CD1-CB 3.56Å; K51-A165 HydrophobicContact CD-CB 4.35Å; K51-A165 WeakPolarHBondContact CD-O 3.42Å; K51-A165 VanDerWaalsContact NZ-C 3.26Å; K51-A165 PolarHBondContact NZ-O 3.1Å; A161-A165 WeakPolarHBondContact O-CB 3.28Å; A161-A165 PolarHBondContact O-N 2.7Å; E162-A165 PolarHBondContact O-N 2.69Å; E162-A165 VanDerWaalsContact O-N 3.16Å; A165-Q167 HydrophobicContact CB-CG 3.87Å; A165-Q167 PolarHBondContact O-N 2.83Å; A165-Q167 PolarHBondContact O-NE2 3.18Å; A165-I169 HydrophobicContact CB-CD1 3.97Å; A165-I169 HydrophobicContact CB-CG1 4.39Å
166E91.5Very high95.5Very high176 Ų17636.6 Ų36.682%0.82218%0.181SC*.THydrogen-bonded Turntrans58.124.5-166.8-55.1176.4132.900112.4E162E162-E166 PolarHBondContact O-N 3.34Å
167Q90.3Very high95.4Very high54 Ų5436.9 Ų36.925%0.25219%0.185SC..SBendtrans-153156.7177.976.5-160.4-107.800110.9A34 A165A34-Q167 HydrophobicContact CB-CG 3.94Å; A165-Q167 HydrophobicContact CB-CG 3.87Å; A165-Q167 PolarHBondContact O-N 2.83Å; A165-Q167 PolarHBondContact O-NE2 3.18Å
168P92.3Very high95.4Very high70 Ų7037 Ų3746%0.45519%0.186SC..  trans-64.8148.7175.7-19.432.4000112.8T32 E162T32-P168 WeakPolarHBondContact CB-O 3.18Å; T32-P168 HydrophobicContact CG2-CB 4.13Å; T32-P168 WeakPolarHBondContact CG2-O 3.36Å; E162-P168 VanDerWaalsContact OE1-CA 3.25Å; E162-P168 WeakPolarHBondContact OE1-CA 3.45Å
169I93.6Very high95.3Very high1 Ų135.1 Ų35.11%0.00518%0.179CC..  trans-123.1128.9179.8-64174.3000110.6A34 M36 I49 R158 A161 E162 A165A34-I169 HydrophobicContact CB-CD1 4.46Å; A34-I169 HydrophobicContact CB-CG1 4.19Å; M36-I169 HydrophobicContact CB-CG2 4.12Å; M36-I169 HydrophobicContact CG-CG2 3.74Å; M36-I169 HydrophobicContact SD-CG2 3.73Å; I49-I169 HydrophobicContact CD1-CD1 3.73Å; R158-I169 WeakPolarHBondContact CD-O 3.42Å; R158-I169 HydrophobicContact CG-CB 4.29Å; A161-I169 HydrophobicContact CB-CD1 3.48Å; A161-I169 VanDerWaalsContact CB-CD1 3.48Å; E162-I169 HydrophobicContact CG-CB 3.97Å; E162-I169 HydrophobicContact CG-CD1 4.25Å; E162-I169 HydrophobicContact CG-CG1 3.97Å; E162-I169 PolarHBondContact OE1-N 3.32Å; A165-I169 HydrophobicContact CB-CD1 3.97Å; A165-I169 HydrophobicContact CB-CG1 4.39Å
170K93.8Very high95.4Very high111 Ų11134.3 Ų34.348%0.48317%0.171SC..  trans-115.8-37.8-178.3-63.9170.4-174.7156.90112.4T32 K198T32-K170 HydrophobicContact CG2-CD 4.03Å; T32-K170 HydrophobicContact CG2-CG 4.35Å; K170-K198 PolarHBondContact O-N 3.34Å
171D96.4Very high95.4Very high27 Ų2734.3 Ų34.314%0.14417%0.171CC..EExtended strand (participates in β ladder)trans-101.3127.4-170.7-81.96.6000111.8V35 M36 K198 L200V35-D171 HydrophobicContact CB-CB 4.49Å; V35-D171 HydrophobicContact CG1-CB 3.85Å; M36-D171 PolarHBondContact N-O 3.24Å; D171-K198 WeakPolarHBondContact CA-O 3.47Å; D171-K198 WeakPolarHBondContact OD1-CB 3.4Å; D171-K198 WeakPolarHBondContact OD1-CD 3.23Å; D171-K198 WeakPolarHBondContact OD1-CG 3.5Å; D171-K198 IonicContact OD1-NZ 3.92Å; D171-K198 PolarHBondContact OD1-NZ 3.23Å; D171-K198 IonicContact OD2-NZ 3.9Å; D171-K198 PolarHBondContact OD2-NZ 2.91Å; D171-L200 HydrophobicContact CB-CD1 4Å; D171-L200 HydrophobicContact CB-CD2 4.3Å; D171-L200 HydrophobicContact CB-CG 4.06Å
172A98.1Very high95.5Very high0 Ų035.1 Ų35.10%018%0.175CC..EExtended strand (participates in β ladder)trans-139.4147.2-176.100000113.3M36 L197 K198 V199 L200M36-A172 HydrophobicContact CG-CB 3.57Å; M36-A172 VanDerWaalsContact O-CA 3.32Å; M36-A172 WeakPolarHBondContact O-CA 3.47Å; M36-A172 HydrophobicContact SD-CB 4.22Å; A172-L197 HydrophobicContact CB-CD1 4.46Å; A172-L197 HydrophobicContact CB-CD2 4.36Å; A172-K198 PolarHBondContact N-O 3.3Å; A172-V199 CarbonylContact O-C 3.53Å; A172-V199 WeakPolarHBondContact O-CA 3.38Å; A172-L200 PolarHBondContact O-N 3.09Å
173V98.8Very high95.5Very high0 Ų033 Ų330%017%0.166CC..EExtended strand (participates in β ladder)trans-104.4130.7160.8171.60000108.9M36 S37 V38 L200 Q201 I203 A419 A423 L426M36-V173 PolarHBondContact O-N 3.36Å; M36-V173 VanDerWaalsContact O-N 3.09Å; S37-V173 CarbonylContact C-O 3.46Å; S37-V173 WeakPolarHBondContact CA-O 3.4Å; S37-V173 WeakPolarHBondContact CB-O 3.2Å; V38-V173 PolarHBondContact N-O 2.84Å; V173-L200 HydrophobicContact CG2-CB 3.95Å; V173-Q201 HydrophobicContact CG1-CB 4.42Å; V173-Q201 HydrophobicContact CG2-CB 4.21Å; V173-I203 HydrophobicContact CG1-CB 4.1Å; V173-I203 HydrophobicContact CG1-CG2 3.57Å; V173-A419 HydrophobicContact CG1-CB 3.96Å; V173-A423 HydrophobicContact CB-CB 4.11Å; V173-A423 HydrophobicContact CG2-CB 3.64Å; V173-L426 HydrophobicContact CG2-CD1 4.33Å
174I98.9Very high95.7Very high0 Ų028.2 Ų28.20%014%0.14CC..EExtended strand (participates in β ladder)trans-116.2132.9-177.9-55.6177.8000108.3L40 L154 V188 A192 V199 Q201 L202 I203L40-I174 HydrophobicContact CB-CG2 4.41Å; L40-I174 HydrophobicContact CD2-CG2 4.07Å; L154-I174 HydrophobicContact CD1-CD1 3.99Å; L154-I174 HydrophobicContact CD2-CD1 3.91Å; I174-V188 HydrophobicContact CG2-CG1 4.18Å; I174-A192 HydrophobicContact CD1-CB 3.96Å; I174-V199 HydrophobicContact CD1-CG2 3.91Å; I174-Q201 PolarHBondContact N-O 3.1Å; I174-Q201 VanDerWaalsContact N-O 3.15Å; I174-L202 HydrophobicContact CB-CD2 3.94Å; I174-L202 HydrophobicContact CG2-CD2 4.49Å; I174-L202 WeakPolarHBondContact O-CA 3.43Å; I174-I203 PolarHBondContact O-N 3.33Å
175T98.8Very high96Very high4 Ų425.7 Ų25.73%0.02513%0.129CC..EExtended strand (participates in β ladder)trans-76.6144.8173.462.60000110.8V38 D39 L40 I203 A208 A415 A419V38-T175 PolarHBondContact O-N 2.9Å; V38-T175 PolarHBondContact O-OG1 3.09Å; D39-T175 VanDerWaalsContact CA-OG1 3.32Å; D39-T175 WeakPolarHBondContact CA-OG1 3.39Å; L40-T175 PolarHBondContact N-OG1 3.26Å; T175-I203 CarbonylContact C-O 2.94Å; T175-I203 VanDerWaalsContact CA-O 3.23Å; T175-I203 WeakPolarHBondContact CA-O 3.32Å; T175-I203 HydrophobicContact CG2-CG2 4.04Å; T175-A208 HydrophobicContact CG2-CB 4.3Å; T175-A415 HydrophobicContact CG2-CB 4.28Å; T175-A419 HydrophobicContact CG2-CB 4.13Å
176V98.4Very high96.3Very high2 Ų227.3 Ų27.31%0.01214%0.135CC..EExtended strand (participates in β ladder)trans-133.1153.2168.9-65.60000110.9V178 F180 V188 L202 I203 N204 D205V176-V178 PolarHBondContact O-N 3.34Å; V176-F180 HydrophobicContact CB-CD2 4.06Å; V176-F180 HydrophobicContact CB-CG 4.48Å; V176-F180 HydrophobicContact CG1-CD2 4.27Å; V176-V188 HydrophobicContact CG1-CB 4.43Å; V176-V188 HydrophobicContact CG1-CG1 4.17Å; V176-V188 HydrophobicContact CG1-CG2 4.11Å; V176-L202 HydrophobicContact CG1-CB 4.32Å; V176-L202 HydrophobicContact CG1-CD1 4.22Å; V176-L202 HydrophobicContact CG1-CD2 4.18Å; V176-L202 HydrophobicContact CG1-CG 4.48Å; V176-L202 HydrophobicContact CG2-CB 4.13Å; V176-I203 PolarHBondContact N-O 2.99Å; V176-N204 WeakPolarHBondContact O-CA 3.37Å; V176-D205 PolarHBondContact O-N 2.79Å
177P97Very high96.6Very high26 Ų2619 Ų1917%0.16910%0.096CC..  trans-60.1135170.9-23.534.5000111.6F179 F180 D205P177-F179 HydrophobicContact CB-CD1 4.13Å; P177-F179 HydrophobicContact CB-CD2 3.97Å; P177-F179 HydrophobicContact CB-CE1 3.75Å; P177-F179 HydrophobicContact CB-CE2 3.58Å; P177-F179 HydrophobicContact CB-CG 4.24Å; P177-F179 HydrophobicContact CB-CZ 3.46Å; P177-F179 VanDerWaalsContact CB-CZ 3.46Å; P177-F179 HydrophobicContact CG-CE2 4.23Å; P177-F179 HydrophobicContact CG-CZ 4.12Å; P177-F179 PolarHBondContact O-N 3.42Å; P177-F180 HydrophobicContact CB-CD1 3.84Å; P177-F180 HydrophobicContact CB-CE1 4.02Å; P177-F180 HydrophobicContact CG-CD1 3.92Å; P177-F180 HydrophobicContact CG-CE1 3.62Å; P177-F180 HydrophobicContact CG-CZ 4.1Å; P177-F180 WeakPolarHBondContact O-CB 3.32Å; P177-F180 PolarHBondContact O-N 2.93Å; P177-D205 WeakPolarHBondContact CA-OD2 3.49Å
178V96.7Very high96.9Very high2 Ų216.4 Ų16.41%0.0128%0.084CC..THydrogen-bonded Turntrans-54-30.3-177.674.90000113.4V176 F180 R185 N204 V239 V264 V442V176-V178 PolarHBondContact O-N 3.34Å; V178-F180 VanDerWaalsContact C-N 3.27Å; V178-F180 PolarHBondContact O-N 3.14Å; V178-R185 PolarHBondContact O-NH2 3.09Å; V178-N204 HydrophobicContact CB-CB 4.17Å; V178-N204 HydrophobicContact CG2-CB 4.13Å; V178-V239 HydrophobicContact CB-CG1 4.44Å; V178-V239 HydrophobicContact CG1-CG1 3.43Å; V178-V239 VanDerWaalsContact CG1-CG1 3.43Å; V178-V239 HydrophobicContact CG1-CG2 4.31Å; V178-V264 HydrophobicContact CB-CG1 4.37Å; V178-V264 HydrophobicContact CG1-CG1 3.49Å; V178-V264 VanDerWaalsContact CG1-CG1 3.49Å; V178-V264 HydrophobicContact CG2-CG1 3.91Å; V178-V264 HydrophobicContact CG2-CG2 4.13Å; V178-V442 HydrophobicContact CG2-CG2 3.82Å
179F96.5Very high97.2Very high8 Ų815.6 Ų15.64%0.0358%0.075CC..THydrogen-bonded Turntrans-78.96.2177.357.9-111.4000115.2P177 N181 S237 V239 F266 R268 Y443P177-F179 HydrophobicContact CB-CD1 4.13Å; P177-F179 HydrophobicContact CB-CD2 3.97Å; P177-F179 HydrophobicContact CB-CE1 3.75Å; P177-F179 HydrophobicContact CB-CE2 3.58Å; P177-F179 HydrophobicContact CB-CG 4.24Å; P177-F179 HydrophobicContact CB-CZ 3.46Å; P177-F179 VanDerWaalsContact CB-CZ 3.46Å; P177-F179 HydrophobicContact CG-CE2 4.23Å; P177-F179 HydrophobicContact CG-CZ 4.12Å; P177-F179 PolarHBondContact O-N 3.42Å; F179-N181 PolarHBondContact O-N 2.93Å; F179-S237 WeakPolarHBondContact CZ-OG 3.28Å; F179-V239 HydrophobicContact CD1-CG2 4.04Å; F179-V239 HydrophobicContact CE1-CG2 3.85Å; F179-F266 HydrophobicContact CB-CD1 3.8Å; F179-F266 HydrophobicContact CB-CD2 3.95Å; F179-F266 HydrophobicContact CB-CE1 3.77Å; F179-F266 HydrophobicContact CB-CE2 3.93Å; F179-F266 HydrophobicContact CB-CG 3.89Å; F179-F266 HydrophobicContact CB-CZ 3.83Å; F179-F266 HydrophobicContact CD1-CB 3.85Å; F179-F266 HydrophobicContact CD1-CD1 4.46Å; F179-F266 HydrophobicContact CD1-CD2 4.07Å; F179-F266 AromaticContact CD1-CG 3.88Å; F179-F266 HydrophobicContact CD1-CG 3.88Å; F179-F266 HydrophobicContact CG-CD2 4.25Å; F179-F266 HydrophobicContact CG-CG 4.29Å; F179-R268 HydrophobicContact CB-CG 4.5Å; F179-R268 HydrophobicContact CD1-CG 4.15Å; F179-R268 HydrophobicContact CD2-CG 3.86Å; F179-R268 VanDerWaalsContact CD2-CZ 3.43Å; F179-R268 HydrophobicContact CE1-CG 4.31Å; F179-R268 HydrophobicContact CE2-CG 4.03Å; F179-R268 HydrophobicContact CG-CG 3.92Å; F179-R268 HydrophobicContact CZ-CG 4.25Å; F179-R268 PolarHBondContact O-NH1 2.95Å; F179-Y443 WeakPolarHBondContact CA-OH 3.47Å; F179-Y443 WeakPolarHBondContact O-CE2 3.37Å; F179-Y443 PolarHBondContact O-OH 2.9Å
180F97.7Very high97.4Very high16 Ų1616.3 Ų16.37%0.078%0.078CC..  trans-71.6122.9174.2-88.325.8000111.5L104 V176 P177 V178 E184 R185 V188L104-F180 HydrophobicContact CD1-CE2 4.29Å; L104-F180 HydrophobicContact CD1-CZ 4.44Å; V176-F180 HydrophobicContact CB-CD2 4.06Å; V176-F180 HydrophobicContact CB-CG 4.48Å; V176-F180 HydrophobicContact CG1-CD2 4.27Å; P177-F180 HydrophobicContact CB-CD1 3.84Å; P177-F180 HydrophobicContact CB-CE1 4.02Å; P177-F180 HydrophobicContact CG-CD1 3.92Å; P177-F180 HydrophobicContact CG-CE1 3.62Å; P177-F180 HydrophobicContact CG-CZ 4.1Å; P177-F180 WeakPolarHBondContact O-CB 3.32Å; P177-F180 PolarHBondContact O-N 2.93Å; V178-F180 VanDerWaalsContact C-N 3.27Å; V178-F180 PolarHBondContact O-N 3.14Å; F180-E184 WeakPolarHBondContact CA-OE2 3.46Å; F180-E184 HydrophobicContact CB-CB 3.88Å; F180-E184 HydrophobicContact CD1-CB 4.27Å; F180-E184 HydrophobicContact CD2-CB 3.71Å; F180-E184 HydrophobicContact CE2-CB 4.25Å; F180-E184 HydrophobicContact CG-CB 3.71Å; F180-R185 HydrophobicContact CB-CG 4.01Å; F180-R185 PolarHBondContact O-NE 3.48Å; F180-R185 PolarHBondContact O-NH2 3.23Å; F180-V188 HydrophobicContact CD2-CG2 4.33Å; F180-V188 HydrophobicContact CE2-CG2 3.93Å
181N97Very high97.6Very high6 Ų611 Ų113%0.0326%0.055CC..  trans-78.3-178.7175.283.711.2000112.4F179 A183 E184 R185 Y443 Y497 F511F179-N181 PolarHBondContact O-N 2.93Å; N181-A183 PolarHBondContact O-N 3.31Å; N181-A183 PolarHBondContact OD1-N 3.09Å; N181-E184 PolarHBondContact N-OE2 2.89Å; N181-E184 PolarHBondContact O-N 2.98Å; N181-E184 WeakPolarHBondContact OD1-CG 3.5Å; N181-E184 PolarHBondContact OD1-N 3.03Å; N181-R185 WeakPolarHBondContact O-CG 3.34Å; N181-R185 PolarHBondContact O-N 2.97Å; N181-Y443 HydrophobicContact CB-CD2 4.41Å; N181-Y443 HydrophobicContact CB-CE2 4.35Å; N181-Y497 WeakPolarHBondContact CB-OH 3.44Å; N181-F511 HydrophobicContact CB-CD2 4.19Å; N181-F511 HydrophobicContact CB-CE2 3.62Å; N181-F511 HydrophobicContact CB-CZ 4.06Å; N181-F511 PolarHBondContact ND2-O 3.28Å; N181-F511 VanDerWaalsContact ND2-O 3.07Å
182Q97.3Very high97.7Very high17 Ų179.7 Ų9.78%0.0795%0.049CC..Hα-helixtrans-61.5-38.7-176.8-64.8-62-55.300113.7R186 Y497 L516 G549Q182-R186 WeakPolarHBondContact O-CB 3.17Å; Q182-R186 WeakPolarHBondContact O-CG 3.27Å; Q182-R186 PolarHBondContact O-N 2.64Å; Q182-R186 PolarHBondContact O-NE 3.23Å; Q182-Y497 WeakPolarHBondContact CB-OH 3.46Å; Q182-Y497 HydrophobicContact CG-CE1 4.3Å; Q182-Y497 WeakPolarHBondContact CG-OH 3.31Å; Q182-Y497 PolarHBondContact N-OH 2.96Å; Q182-L516 HydrophobicContact CB-CD2 3.77Å; Q182-L516 HydrophobicContact CG-CD1 4.35Å; Q182-L516 HydrophobicContact CG-CD2 3.81Å; Q182-G549 PolarHBondContact NE2-O 3.06Å
183A96.2Very high97.6Very high5 Ų516 Ų164%0.0417%0.072CC..Hα-helixtrans-68.9-42176.100000111.7N181 R186 A187 D645 L646N181-A183 PolarHBondContact O-N 3.31Å; N181-A183 PolarHBondContact OD1-N 3.09Å; A183-R186 PolarHBondContact O-N 3.44Å; A183-A187 WeakPolarHBondContact O-CB 2.82Å; A183-A187 PolarHBondContact O-N 3.31Å; A183-D645 PolarHBondContact N-OD2 3.45Å; A183-L646 HydrophobicContact CB-CB 3.89Å; A183-L646 HydrophobicContact CB-CD2 4.41Å
184E97.6Very high97.6Very high3 Ų316.3 Ų16.31%0.0147%0.074CC..Hα-helixtrans-64.2-40.3177.4-64.5174.9131.800111.5K106 F180 N181 A187 V188 R268K106-E184 WeakPolarHBondContact CE-OE1 3.38Å; K106-E184 IonicContact NZ-OE1 3.35Å; K106-E184 PolarHBondContact NZ-OE1 3.09Å; F180-E184 WeakPolarHBondContact CA-OE2 3.46Å; F180-E184 HydrophobicContact CB-CB 3.88Å; F180-E184 HydrophobicContact CD1-CB 4.27Å; F180-E184 HydrophobicContact CD2-CB 3.71Å; F180-E184 HydrophobicContact CE2-CB 4.25Å; F180-E184 HydrophobicContact CG-CB 3.71Å; N181-E184 PolarHBondContact N-OE2 2.89Å; N181-E184 PolarHBondContact O-N 2.98Å; N181-E184 WeakPolarHBondContact OD1-CG 3.5Å; N181-E184 PolarHBondContact OD1-N 3.03Å; E184-A187 PolarHBondContact O-N 3.47Å; E184-V188 PolarHBondContact O-N 3.25Å; E184-R268 IonicContact OE1-CZ 2.75Å; E184-R268 IonicContact OE1-NH1 3.71Å; E184-R268 PolarHBondContact OE1-NH1 3.29Å; E184-R268 IonicContact OE1-NH2 2.66Å; E184-R268 PolarHBondContact OE1-NH2 3.08Å; E184-R268 IonicContact OE2-CZ 3.22Å; E184-R268 IonicContact OE2-NH1 3.73Å; E184-R268 PolarHBondContact OE2-NH1 2.93Å; E184-R268 IonicContact OE2-NH2 3.26Å
185R98Very high97.5Very high10 Ų1016.6 Ų16.64%0.0388%0.076CC..Hα-helixtrans-66.6-44.3173.6-69.9178.7-170.7-96.9-15.2112.2V178 F180 N181 A187 V188 L189 L202 N204 S548 V550V178-R185 PolarHBondContact O-NH2 3.09Å; F180-R185 HydrophobicContact CB-CG 4.01Å; F180-R185 PolarHBondContact O-NE 3.48Å; F180-R185 PolarHBondContact O-NH2 3.23Å; N181-R185 WeakPolarHBondContact O-CG 3.34Å; N181-R185 PolarHBondContact O-N 2.97Å; R185-A187 VanDerWaalsContact C-N 3.33Å; R185-A187 PolarHBondContact O-N 3.39Å; R185-V188 PolarHBondContact O-N 3.11Å; R185-L189 PolarHBondContact O-N 2.75Å; R185-L189 VanDerWaalsContact O-N 3.08Å; R185-L202 HydrophobicContact CB-CD1 3.98Å; R185-L202 HydrophobicContact CG-CD1 4.31Å; R185-N204 PolarHBondContact NH1-OD1 3.36Å; R185-N204 PolarHBondContact NH2-OD1 3.33Å; R185-S548 PolarHBondContact NH1-O 3.49Å; R185-V550 HydrophobicContact CB-CG2 3.95Å
186R97.1Very high97.3Very high36 Ų3618.6 Ų18.614%0.13610%0.097CC..Hα-helixtrans-63.3-35.7176-76.4-175.8-64.5121-3.1112.7Q182 A183 V188 L189 Q190 D645 L646 D648Q182-R186 WeakPolarHBondContact O-CB 3.17Å; Q182-R186 WeakPolarHBondContact O-CG 3.27Å; Q182-R186 PolarHBondContact O-N 2.64Å; Q182-R186 PolarHBondContact O-NE 3.23Å; A183-R186 PolarHBondContact O-N 3.44Å; R186-V188 VanDerWaalsContact C-N 3.33Å; R186-V188 PolarHBondContact O-N 3.45Å; R186-L189 PolarHBondContact O-N 2.98Å; R186-Q190 VanDerWaalsContact O-CG 3.32Å; R186-Q190 WeakPolarHBondContact O-CG 3.37Å; R186-Q190 PolarHBondContact O-N 2.98Å; R186-D645 IonicContact CZ-OD1 3.3Å; R186-D645 IonicContact CZ-OD2 2.89Å; R186-D645 IonicContact NH2-OD1 2.81Å; R186-D645 PolarHBondContact NH2-OD1 2.87Å; R186-D645 IonicContact NH2-OD2 2.76Å; R186-D645 PolarHBondContact NH2-OD2 3.15Å; R186-L646 PolarHBondContact NH1-O 2.86Å; R186-L646 PolarHBondContact NH2-O 3.24Å; R186-D648 IonicContact CZ-OD1 2.63Å; R186-D648 IonicContact NH1-OD1 2.62Å; R186-D648 PolarHBondContact NH1-OD1 2.95Å; R186-D648 IonicContact NH1-OD2 2.64Å
187A97.4Very high97.3Very high1 Ų119 Ų191%0.00810%0.099CC..Hα-helixtrans-60.3-39.9173.700000112.6L104 E147 A183 E184 R185 Q190 A191L104-A187 HydrophobicContact CB-CB 4.04Å; L104-A187 HydrophobicContact CD2-CB 4.29Å; E147-A187 HydrophobicContact CG-CB 3.85Å; A183-A187 WeakPolarHBondContact O-CB 2.82Å; A183-A187 PolarHBondContact O-N 3.31Å; E184-A187 PolarHBondContact O-N 3.47Å; R185-A187 VanDerWaalsContact C-N 3.33Å; R185-A187 PolarHBondContact O-N 3.39Å; A187-Q190 PolarHBondContact O-N 3.1Å; A187-A191 PolarHBondContact O-N 2.94Å
188V98.5Very high97.3Very high0 Ų023.2 Ų23.20%012%0.115CC..Hα-helixtrans-67.5-41.3173.7178.90000111.6L104 L150 I174 V176 F180 E184 R185 R186 Q190 A191 A192 L202L104-V188 HydrophobicContact CD1-CG2 4.1Å; L150-V188 HydrophobicContact CD2-CB 4.45Å; L150-V188 HydrophobicContact CD2-CG1 4.39Å; L150-V188 HydrophobicContact CD2-CG2 4.12Å; I174-V188 HydrophobicContact CG2-CG1 4.18Å; V176-V188 HydrophobicContact CG1-CB 4.43Å; V176-V188 HydrophobicContact CG1-CG1 4.17Å; V176-V188 HydrophobicContact CG1-CG2 4.11Å; F180-V188 HydrophobicContact CD2-CG2 4.33Å; F180-V188 HydrophobicContact CE2-CG2 3.93Å; E184-V188 PolarHBondContact O-N 3.25Å; R185-V188 PolarHBondContact O-N 3.11Å; R186-V188 VanDerWaalsContact C-N 3.33Å; R186-V188 PolarHBondContact O-N 3.45Å; V188-Q190 PolarHBondContact O-N 3.04Å; V188-A191 PolarHBondContact O-N 2.99Å; V188-A192 PolarHBondContact O-N 3.43Å; V188-L202 HydrophobicContact CB-CD1 4.36Å; V188-L202 HydrophobicContact CG1-CD1 4.47Å; V188-L202 HydrophobicContact CG1-CD2 3.77Å
189L98.1Very high97.4Very high52 Ų5224.6 Ų24.627%0.27212%0.124SC..Hα-helixtrans-62.9-40.1175.2-66.8-179.6000112.5R185 R186 A192 R193 V199 L202 V550R185-L189 PolarHBondContact O-N 2.75Å; R185-L189 VanDerWaalsContact O-N 3.08Å; R186-L189 PolarHBondContact O-N 2.98Å; L189-A192 PolarHBondContact O-N 3Å; L189-R193 WeakPolarHBondContact O-CB 3.47Å; L189-R193 PolarHBondContact O-N 3.5Å; L189-V199 HydrophobicContact CD2-CB 3.85Å; L189-V199 HydrophobicContact CD2-CG1 3.78Å; L189-V199 HydrophobicContact CD2-CG2 3.94Å; L189-L202 HydrophobicContact CD2-CD1 3.93Å; L189-L202 HydrophobicContact CD2-CD2 4.12Å; L189-L202 HydrophobicContact CD2-CG 3.88Å; L189-L202 HydrophobicContact CG-CD1 3.96Å; L189-L202 HydrophobicContact CG-CG 4.46Å; L189-V550 HydrophobicContact CD1-CG2 4.21Å
190Q97Very high97.4Very high16 Ų1625.9 Ų25.98%0.07513%0.13CC..Hα-helixtrans-63.5-44.9174.9-72170.222.600111.4R186 A187 V188 A192 R193 M194 D648R186-Q190 VanDerWaalsContact O-CG 3.32Å; R186-Q190 WeakPolarHBondContact O-CG 3.37Å; R186-Q190 PolarHBondContact O-N 2.98Å; A187-Q190 PolarHBondContact O-N 3.1Å; V188-Q190 PolarHBondContact O-N 3.04Å; Q190-A192 VanDerWaalsContact C-N 3.35Å; Q190-A192 PolarHBondContact O-N 3.1Å; Q190-R193 CarbonylContact O-C 3.58Å; Q190-R193 WeakPolarHBondContact O-CB 3.39Å; Q190-R193 PolarHBondContact O-N 3.23Å; Q190-M194 WeakPolarHBondContact O-CG 3.49Å; Q190-M194 PolarHBondContact O-N 3.48Å; Q190-D648 PolarHBondContact NE2-OD1 3.49Å
191A98.3Very high97.5Very high0 Ų025.5 Ų25.50%013%0.129CC..Hα-helixtrans-60.9-41.6175.700000112.6E147 L150 G151 L154 A187 V188 M194 A195E147-A191 HydrophobicContact CB-CB 4.48Å; E147-A191 WeakPolarHBondContact O-CB 3.46Å; L150-A191 HydrophobicContact CB-CB 3.69Å; L150-A191 HydrophobicContact CD2-CB 3.6Å; L150-A191 HydrophobicContact CG-CB 3.55Å; G151-A191 WeakPolarHBondContact CA-O 3.47Å; L154-A191 HydrophobicContact CD1-CB 4.18Å; A187-A191 PolarHBondContact O-N 2.94Å; V188-A191 PolarHBondContact O-N 2.99Å; A191-M194 WeakPolarHBondContact O-CB 3.48Å; A191-M194 PolarHBondContact O-N 3Å; A191-A195 PolarHBondContact O-N 3.03Å
192A98.4Very high97.6Very high0 Ų025.2 Ų25.20%013%0.127CC..Hα-helixtrans-65-39.517400000112.1L154 I174 V188 L189 Q190 M194 A195 G196 L197 V199L154-A192 HydrophobicContact CD1-CB 4.02Å; I174-A192 HydrophobicContact CD1-CB 3.96Å; V188-A192 PolarHBondContact O-N 3.43Å; L189-A192 PolarHBondContact O-N 3Å; Q190-A192 VanDerWaalsContact C-N 3.35Å; Q190-A192 PolarHBondContact O-N 3.1Å; A192-M194 VanDerWaalsContact C-N 3.33Å; A192-M194 PolarHBondContact O-N 3.43Å; A192-A195 CarbonylContact O-C 3.58Å; A192-A195 WeakPolarHBondContact O-CB 3.42Å; A192-A195 PolarHBondContact O-N 3Å; A192-A195 VanDerWaalsContact O-N 3.17Å; A192-G196 PolarHBondContact O-N 2.82Å; A192-G196 VanDerWaalsContact O-N 3.09Å; A192-L197 HydrophobicContact CB-CB 4.38Å; A192-L197 PolarHBondContact O-N 2.89Å; A192-V199 HydrophobicContact CB-CG2 3.41Å; A192-V199 VanDerWaalsContact CB-CG2 3.41Å
193R97Very high97.6Very high132 Ų13224.4 Ų24.450%0.49812%0.124SC..Hα-helixtrans-62.3-38.5173.1-170.5171.1-178.3-145-3.9111.7L189 Q190 G196 E651 L654L189-R193 WeakPolarHBondContact O-CB 3.47Å; L189-R193 PolarHBondContact O-N 3.5Å; Q190-R193 CarbonylContact O-C 3.58Å; Q190-R193 WeakPolarHBondContact O-CB 3.39Å; Q190-R193 PolarHBondContact O-N 3.23Å; R193-G196 PolarHBondContact O-N 3.12Å; R193-E651 IonicContact CZ-OE1 2.69Å; R193-E651 IonicContact CZ-OE2 3.14Å; R193-E651 IonicContact NH1-OE1 2.73Å; R193-E651 PolarHBondContact NH1-OE1 3.09Å; R193-E651 IonicContact NH1-OE2 2.75Å; R193-E651 PolarHBondContact NH1-OE2 3.3Å; R193-E651 IonicContact NH2-OE1 3.88Å; R193-E651 PolarHBondContact NH2-OE1 2.86Å; R193-E651 IonicContact NH2-OE2 2.66Å; R193-L654 HydrophobicContact CG-CD2 4.39Å
194M97.5Very high97.7Very high7 Ų724.2 Ų24.23%0.03412%0.122CC..Hα-helixtrans-65.5-35.9172.5-68.1175.7-170.600112.9E147 E148 Q190 A191 A192 G196 L649 L654 V658 L661E147-M194 HydrophobicContact CB-CE 4.4Å; E148-M194 HydrophobicContact CB-SD 4.41Å; E148-M194 HydrophobicContact CG-CE 4.25Å; E148-M194 HydrophobicContact CG-SD 3.86Å; Q190-M194 WeakPolarHBondContact O-CG 3.49Å; Q190-M194 PolarHBondContact O-N 3.48Å; A191-M194 WeakPolarHBondContact O-CB 3.48Å; A191-M194 PolarHBondContact O-N 3Å; A192-M194 VanDerWaalsContact C-N 3.33Å; A192-M194 PolarHBondContact O-N 3.43Å; M194-G196 PolarHBondContact O-N 3.27Å; M194-L649 HydrophobicContact CE-CD2 4.15Å; M194-L654 HydrophobicContact CE-CD1 3.61Å; M194-L654 HydrophobicContact CG-CD1 3.6Å; M194-L654 HydrophobicContact SD-CD1 4.46Å; M194-V658 HydrophobicContact CG-CG2 4.4Å; M194-L661 HydrophobicContact CB-CD1 4.12Å
195A96.9Very high97.7Very high5 Ų525.1 Ų25.14%0.04113%0.127CC..Hα-helixtrans-73-12173.300000113.6L154 N155 R158 A191 A192 L197L154-A195 HydrophobicContact CB-CB 3.84Å; N155-A195 HydrophobicContact CB-CB 4.16Å; R158-A195 VanDerWaalsContact CZ-O 3.27Å; R158-A195 PolarHBondContact NH1-O 2.98Å; R158-A195 PolarHBondContact NH2-O 3.36Å; R158-A195 VanDerWaalsContact NH2-O 3.13Å; A191-A195 PolarHBondContact O-N 3.03Å; A192-A195 CarbonylContact O-C 3.58Å; A192-A195 WeakPolarHBondContact O-CB 3.42Å; A192-A195 PolarHBondContact O-N 3Å; A192-A195 VanDerWaalsContact O-N 3.17Å; A195-L197 HydrophobicContact CB-CD1 4.39Å; A195-L197 HydrophobicContact CB-CG 4.36Å
196G95.7Very high97.7Very high46 Ų4624.7 Ų24.747%0.47413%0.125SC..THydrogen-bonded Turntrans73.327.2-172.900000113.6R158 A192 R193 M194R158-G196 PolarHBondContact NH1-O 3.36Å; A192-G196 PolarHBondContact O-N 2.82Å; A192-G196 VanDerWaalsContact O-N 3.09Å; R193-G196 PolarHBondContact O-N 3.12Å; M194-G196 PolarHBondContact O-N 3.27Å
197L97.3Very high97.7Very high11 Ų1123 Ų236%0.05812%0.119CC..  trans-96.7133.1173.5-71.8173.6000110.8M36 L154 R158 A172 A192 A195M36-L197 HydrophobicContact SD-CD2 4.06Å; L154-L197 HydrophobicContact CB-CD1 4.19Å; R158-L197 HydrophobicContact CB-CD2 4.21Å; R158-L197 HydrophobicContact CG-CD2 4.07Å; A172-L197 HydrophobicContact CB-CD1 4.46Å; A172-L197 HydrophobicContact CB-CD2 4.36Å; A192-L197 HydrophobicContact CB-CB 4.38Å; A192-L197 PolarHBondContact O-N 2.89Å; A195-L197 HydrophobicContact CB-CD1 4.39Å; A195-L197 HydrophobicContact CB-CG 4.36Å
198K97Very high97.8Very high114 Ų11423 Ų2350%0.49612%0.119SC..EExtended strand (participates in β ladder)trans-85.9107.3165.7167163.4152.9-86.40108.6K170 D171 A172 L200K170-K198 PolarHBondContact O-N 3.34Å; D171-K198 WeakPolarHBondContact CA-O 3.47Å; D171-K198 WeakPolarHBondContact OD1-CB 3.4Å; D171-K198 WeakPolarHBondContact OD1-CD 3.23Å; D171-K198 WeakPolarHBondContact OD1-CG 3.5Å; D171-K198 IonicContact OD1-NZ 3.92Å; D171-K198 PolarHBondContact OD1-NZ 3.23Å; D171-K198 IonicContact OD2-NZ 3.9Å; D171-K198 PolarHBondContact OD2-NZ 2.91Å; A172-K198 PolarHBondContact N-O 3.3Å; K198-L200 PolarHBondContact O-N 3.03Å
199V98.3Very high97.8Very high32 Ų3223.1 Ų23.119%0.19412%0.12CC..EExtended strand (participates in β ladder)trans-70.1117.6173.4177.20000108.6A172 I174 L189 A192 Q201 L202A172-V199 CarbonylContact O-C 3.53Å; A172-V199 WeakPolarHBondContact O-CA 3.38Å; I174-V199 HydrophobicContact CD1-CG2 3.91Å; L189-V199 HydrophobicContact CD2-CB 3.85Å; L189-V199 HydrophobicContact CD2-CG1 3.78Å; L189-V199 HydrophobicContact CD2-CG2 3.94Å; A192-V199 HydrophobicContact CB-CG2 3.41Å; A192-V199 VanDerWaalsContact CB-CG2 3.41Å; V199-Q201 VanDerWaalsContact CG1-C 3.45Å; V199-Q201 WeakPolarHBondContact CG1-O 3.31Å; V199-L202 HydrophobicContact CG1-CD2 3.83Å; V199-L202 HydrophobicContact CG1-CG 4.18Å
200L97.8Very high97.8Very high34 Ų3420.6 Ų20.618%0.17811%0.107CC..EExtended strand (participates in β ladder)trans-75.9-36.2170.7-67.6-179.4000111.2D171 A172 V173 K198 A423 L426D171-L200 HydrophobicContact CB-CD1 4Å; D171-L200 HydrophobicContact CB-CD2 4.3Å; D171-L200 HydrophobicContact CB-CG 4.06Å; A172-L200 PolarHBondContact O-N 3.09Å; V173-L200 HydrophobicContact CG2-CB 3.95Å; K198-L200 PolarHBondContact O-N 3.03Å; L200-A423 HydrophobicContact CD1-CB 4.46Å; L200-L426 HydrophobicContact CB-CB 4.3Å; L200-L426 HydrophobicContact CB-CD1 3.95Å; L200-L426 HydrophobicContact CD1-CB 4.12Å
201Q98.5Very high97.8Very high8 Ų819.9 Ų19.94%0.03710%0.103CC..EExtended strand (participates in β ladder)trans-161.7143.9176-171.3176.4-2.800110.6V173 I174 V199 L426 E547V173-Q201 HydrophobicContact CG1-CB 4.42Å; V173-Q201 HydrophobicContact CG2-CB 4.21Å; I174-Q201 PolarHBondContact N-O 3.1Å; I174-Q201 VanDerWaalsContact N-O 3.15Å; V199-Q201 VanDerWaalsContact CG1-C 3.45Å; V199-Q201 WeakPolarHBondContact CG1-O 3.31Å; Q201-L426 HydrophobicContact CB-CD1 3.74Å; Q201-E547 HydrophobicContact CG-CB 3.96Å; Q201-E547 WeakPolarHBondContact CG-O 3.49Å; Q201-E547 PolarHBondContact NE2-O 3.42Å
202L98.8Very high97.8Very high0 Ų020.2 Ų20.20%011%0.105CC..EExtended strand (participates in β ladder)trans-89104.8154-59-177.6000109.4I174 V176 R185 V188 L189 V199 S548I174-L202 HydrophobicContact CB-CD2 3.94Å; I174-L202 HydrophobicContact CG2-CD2 4.49Å; I174-L202 WeakPolarHBondContact O-CA 3.43Å; V176-L202 HydrophobicContact CG1-CB 4.32Å; V176-L202 HydrophobicContact CG1-CD1 4.22Å; V176-L202 HydrophobicContact CG1-CD2 4.18Å; V176-L202 HydrophobicContact CG1-CG 4.48Å; V176-L202 HydrophobicContact CG2-CB 4.13Å; R185-L202 HydrophobicContact CB-CD1 3.98Å; R185-L202 HydrophobicContact CG-CD1 4.31Å; V188-L202 HydrophobicContact CB-CD1 4.36Å; V188-L202 HydrophobicContact CG1-CD1 4.47Å; V188-L202 HydrophobicContact CG1-CD2 3.77Å; L189-L202 HydrophobicContact CD2-CD1 3.93Å; L189-L202 HydrophobicContact CD2-CD2 4.12Å; L189-L202 HydrophobicContact CD2-CG 3.88Å; L189-L202 HydrophobicContact CG-CD1 3.96Å; L189-L202 HydrophobicContact CG-CG 4.46Å; V199-L202 HydrophobicContact CG1-CD2 3.83Å; V199-L202 HydrophobicContact CG1-CG 4.18Å; L202-S548 PolarHBondContact N-OG 3.02Å; L202-S548 VanDerWaalsContact N-OG 3.1Å; L202-S548 WeakPolarHBondContact O-CA 3.45Å
203I98.7Very high97.8Very high0 Ų021.3 Ų21.30%011%0.11CC..EExtended strand (participates in β ladder)trans-91144.3178.2-168.9165.8000109.8V173 I174 T175 V176 T207 A208 L211 A419 Q422V173-I203 HydrophobicContact CG1-CB 4.1Å; V173-I203 HydrophobicContact CG1-CG2 3.57Å; I174-I203 PolarHBondContact O-N 3.33Å; T175-I203 CarbonylContact C-O 2.94Å; T175-I203 VanDerWaalsContact CA-O 3.23Å; T175-I203 WeakPolarHBondContact CA-O 3.32Å; T175-I203 HydrophobicContact CG2-CG2 4.04Å; V176-I203 PolarHBondContact N-O 2.99Å; I203-T207 HydrophobicContact CD1-CG2 4.35Å; I203-T207 HydrophobicContact CG1-CG2 4.21Å; I203-A208 HydrophobicContact CD1-CB 3.86Å; I203-A208 HydrophobicContact CG1-CB 4.11Å; I203-A208 HydrophobicContact CG2-CB 3.94Å; I203-L211 HydrophobicContact CD1-CD2 4.42Å; I203-A419 HydrophobicContact CG2-CB 4.05Å; I203-Q422 HydrophobicContact CD1-CB 4.33Å; I203-Q422 HydrophobicContact CD1-CG 4.29Å
204N98.6Very high97.8Very high2 Ų215 Ų151%0.0119%0.086CC..EExtended strand (participates in β ladder)trans-72138.7173.4-61.9-34.8000109.8V176 V178 R185 N206 T207 A208 D439 Y476V176-N204 WeakPolarHBondContact O-CA 3.37Å; V178-N204 HydrophobicContact CB-CB 4.17Å; V178-N204 HydrophobicContact CG2-CB 4.13Å; R185-N204 PolarHBondContact NH1-OD1 3.36Å; R185-N204 PolarHBondContact NH2-OD1 3.33Å; N204-N206 PolarHBondContact O-N 3.11Å; N204-T207 CarbonylContact O-C 3.53Å; N204-T207 WeakPolarHBondContact O-CA 3.37Å; N204-T207 WeakPolarHBondContact O-CB 3.26Å; N204-T207 PolarHBondContact O-N 3.1Å; N204-A208 PolarHBondContact O-N 2.92Å; N204-D439 PolarHBondContact ND2-OD1 2.81Å; N204-D439 PolarHBondContact ND2-OD2 2.89Å; N204-Y476 PolarHBondContact ND2-OH 2.79Å; N204-Y476 VanDerWaalsContact ND2-OH 3.09Å
205D96.1Very high97.7Very high21 Ų2115.8 Ų15.811%0.1129%0.091CC..Hα-helixtrans-41.6-59.8178.448.28.1000114.2V176 P177 T207 A208 T209V176-D205 PolarHBondContact O-N 2.79Å; P177-D205 WeakPolarHBondContact CA-OD2 3.49Å; D205-T207 VanDerWaalsContact C-N 3.33Å; D205-T207 PolarHBondContact O-N 3.28Å; D205-A208 PolarHBondContact O-N 2.68Å; D205-T209 PolarHBondContact O-N 2.77Å; D205-T209 PolarHBondContact O-OG1 3.26Å
206N97.8Very high97.5Very high1 Ų122.9 Ų22.91%0.00512%0.121CC..Hα-helixtrans-69.5-27.2178.6-92.3-15.8000113.3N204 T209 A210 V239 T241N204-N206 PolarHBondContact O-N 3.11Å; N206-T209 PolarHBondContact O-N 3.05Å; N206-A210 WeakPolarHBondContact O-CB 3.45Å; N206-A210 PolarHBondContact O-N 3.21Å; N206-V239 WeakPolarHBondContact ND2-CG1 3.35Å; N206-V239 PolarHBondContact ND2-O 3.37Å; N206-V239 VanDerWaalsContact ND2-O 3.12Å; N206-T241 HydrophobicContact CB-CG2 4.21Å; N206-T241 WeakPolarHBondContact CB-OG1 3.34Å; N206-T241 PolarHBondContact ND2-OG1 3.16Å
207T98.6Very high97.4Very high2 Ų224.8 Ų24.81%0.01211%0.114CC..Hα-helixtrans-67.8-37.4173-57.80000111.2I203 N204 D205 L211 L259 I261 V437 D439I203-T207 HydrophobicContact CD1-CG2 4.35Å; I203-T207 HydrophobicContact CG1-CG2 4.21Å; N204-T207 CarbonylContact O-C 3.53Å; N204-T207 WeakPolarHBondContact O-CA 3.37Å; N204-T207 WeakPolarHBondContact O-CB 3.26Å; N204-T207 PolarHBondContact O-N 3.1Å; D205-T207 VanDerWaalsContact C-N 3.33Å; D205-T207 PolarHBondContact O-N 3.28Å; T207-L211 WeakPolarHBondContact O-CB 3.42Å; T207-L211 PolarHBondContact O-N 2.86Å; T207-L259 HydrophobicContact CG2-CD1 4.17Å; T207-I261 HydrophobicContact CG2-CD1 4.37Å; T207-V437 HydrophobicContact CG2-CG1 3.82Å; T207-D439 WeakPolarHBondContact CB-OD2 3.41Å; T207-D439 HydrophobicContact CG2-CB 4.4Å; T207-D439 VanDerWaalsContact CG2-OD2 3.31Å; T207-D439 WeakPolarHBondContact CG2-OD2 3.36Å; T207-D439 VanDerWaalsContact OG1-CG 3.25Å; T207-D439 PolarHBondContact OG1-OD2 3.41Å
208A98.6Very high97.3Very high0 Ų026.6 Ų26.60%012%0.12CC..Hα-helixtrans-68.3-44.6174.600000111.3T175 I203 N204 D205 A210 L211 S212 A415 G418 A419T175-A208 HydrophobicContact CG2-CB 4.3Å; I203-A208 HydrophobicContact CD1-CB 3.86Å; I203-A208 HydrophobicContact CG1-CB 4.11Å; I203-A208 HydrophobicContact CG2-CB 3.94Å; N204-A208 PolarHBondContact O-N 2.92Å; D205-A208 PolarHBondContact O-N 2.68Å; A208-A210 VanDerWaalsContact C-N 3.34Å; A208-A210 PolarHBondContact O-N 3.21Å; A208-L211 PolarHBondContact O-N 2.79Å; A208-S212 PolarHBondContact O-N 2.82Å; A208-A415 HydrophobicContact CB-CB 4.41Å; A208-A415 WeakPolarHBondContact CB-O 3.45Å; A208-G418 WeakPolarHBondContact O-CA 3.46Å; A208-A419 HydrophobicContact CB-CB 4.37Å
209T98.4Very high97.1Very high2 Ų230.8 Ų30.81%0.01214%0.139CC..Hα-helixtrans-58.6-43.5173.1-68.20000112.2D205 N206 S212 Y213 F230 V383 I409 A414 A415D205-T209 PolarHBondContact O-N 2.77Å; D205-T209 PolarHBondContact O-OG1 3.26Å; N206-T209 PolarHBondContact O-N 3.05Å; T209-S212 WeakPolarHBondContact O-CB 3.25Å; T209-S212 PolarHBondContact O-N 3.11Å; T209-Y213 PolarHBondContact O-N 3.18Å; T209-F230 HydrophobicContact CG2-CD1 3.87Å; T209-F230 HydrophobicContact CG2-CE1 4.18Å; T209-V383 HydrophobicContact CG2-CG1 4.06Å; T209-V383 HydrophobicContact CG2-CG2 3.78Å; T209-I409 HydrophobicContact CG2-CD1 4.1Å; T209-A414 HydrophobicContact CG2-CB 3.78Å; T209-A415 PolarHBondContact OG1-N 2.73Å
210A98.3Very high96.9Very high0 Ų033.6 Ų33.60%015%0.152CC..Hα-helixtrans-64.2-39.6174.300000112.7N206 A208 S212 Y213 G214 F230 V243 Y245 L259N206-A210 WeakPolarHBondContact O-CB 3.45Å; N206-A210 PolarHBondContact O-N 3.21Å; A208-A210 VanDerWaalsContact C-N 3.34Å; A208-A210 PolarHBondContact O-N 3.21Å; A210-S212 VanDerWaalsContact C-N 3.35Å; A210-S212 PolarHBondContact O-N 2.95Å; A210-Y213 PolarHBondContact O-N 2.73Å; A210-G214 PolarHBondContact O-N 3.14Å; A210-F230 HydrophobicContact CB-CD2 4.19Å; A210-F230 HydrophobicContact CB-CE2 3.82Å; A210-F230 HydrophobicContact CB-CZ 4.16Å; A210-V243 HydrophobicContact CB-CG1 4.33Å; A210-V243 HydrophobicContact CB-CG2 4.03Å; A210-Y245 VanDerWaalsContact CA-OH 3.25Å; A210-Y245 WeakPolarHBondContact CA-OH 3.27Å; A210-Y245 VanDerWaalsContact CB-OH 3.3Å; A210-Y245 WeakPolarHBondContact CB-OH 3.39Å; A210-Y245 PolarHBondContact O-OH 3.29Å; A210-L259 HydrophobicContact CB-CD2 4.37Å
211L98.3Very high96.8Very high0 Ų032.5 Ų32.50%015%0.146CC..Hα-helixtrans-62.5-43.1174.5-179.857.2000111.3I203 T207 A208 G214 V215 L259 G418 Y421 Q422 F435 V437I203-L211 HydrophobicContact CD1-CD2 4.42Å; T207-L211 WeakPolarHBondContact O-CB 3.42Å; T207-L211 PolarHBondContact O-N 2.86Å; A208-L211 PolarHBondContact O-N 2.79Å; L211-G214 PolarHBondContact O-N 3.36Å; L211-V215 HydrophobicContact CD1-CG2 3.88Å; L211-V215 HydrophobicContact CG-CG2 4.35Å; L211-V215 VanDerWaalsContact O-CB 3.31Å; L211-V215 WeakPolarHBondContact O-CB 3.47Å; L211-V215 WeakPolarHBondContact O-CG2 3.49Å; L211-V215 PolarHBondContact O-N 3.05Å; L211-L259 VanDerWaalsContact CA-CD2 3.46Å; L211-L259 HydrophobicContact CB-CD2 3.83Å; L211-L259 HydrophobicContact CD1-CD2 4.07Å; L211-G418 WeakPolarHBondContact CD2-O 3.45Å; L211-Y421 HydrophobicContact CD1-CD1 4.34Å; L211-Y421 HydrophobicContact CD2-CD1 4.3Å; L211-Y421 HydrophobicContact CG-CD1 4.39Å; L211-Q422 HydrophobicContact CD2-CB 3.89Å; L211-F435 HydrophobicContact CD1-CB 4.21Å; L211-F435 HydrophobicContact CD1-CD1 3.64Å; L211-F435 HydrophobicContact CD1-CE1 4.2Å; L211-F435 HydrophobicContact CD1-CG 3.91Å; L211-V437 HydrophobicContact CD1-CG2 3.92Å; L211-V437 HydrophobicContact CD2-CG2 4.07Å
212S97.8Very high96.7Very high7 Ų735 Ų355%0.04916%0.16CC..Hα-helixtrans-58.3-52.6174.7-167.10000111.3A208 T209 A210 G214 V215 F216 A414A208-S212 PolarHBondContact O-N 2.82Å; T209-S212 WeakPolarHBondContact O-CB 3.25Å; T209-S212 PolarHBondContact O-N 3.11Å; A210-S212 VanDerWaalsContact C-N 3.35Å; A210-S212 PolarHBondContact O-N 2.95Å; S212-G214 PolarHBondContact O-N 3.39Å; S212-V215 PolarHBondContact O-N 2.66Å; S212-F216 WeakPolarHBondContact O-CD2 3.23Å; S212-F216 PolarHBondContact O-N 3.12Å; S212-A414 WeakPolarHBondContact CB-O 3.41Å; S212-A414 PolarHBondContact OG-O 3.31Å
213Y97.7Very high96.4Very high23 Ų2340.2 Ų40.29%0.0919%0.192CC..Hα-helixtrans-52-54.1175.1179.4-94.5000112.3T209 A210 V215 F216 R217 I228 F230 Y245 I381T209-Y213 PolarHBondContact O-N 3.18Å; A210-Y213 PolarHBondContact O-N 2.73Å; Y213-V215 PolarHBondContact O-N 2.89Å; Y213-F216 PolarHBondContact O-N 3.01Å; Y213-R217 WeakPolarHBondContact O-CB 3.47Å; Y213-R217 PolarHBondContact O-N 2.9Å; Y213-R217 PolarHBondContact OH-NH1 3.08Å; Y213-I228 HydrophobicContact CE1-CG1 4.21Å; Y213-F230 AromaticContact CD1-CZ 3.94Å; Y213-F230 HydrophobicContact CD1-CZ 3.94Å; Y213-F230 HydrophobicContact CD2-CE1 4.4Å; Y213-F230 HydrophobicContact CD2-CZ 4.35Å; Y213-F230 HydrophobicContact CG-CE1 4.16Å; Y213-F230 AromaticContact CG-CZ 3.8Å; Y213-F230 HydrophobicContact CG-CZ 3.8Å; Y213-Y245 HydrophobicContact CD1-CE1 4.35Å; Y213-Y245 AromaticContact CD1-CE2 3.86Å; Y213-Y245 HydrophobicContact CD1-CE2 3.86Å; Y213-Y245 AromaticContact CD1-CZ 3.65Å; Y213-Y245 WeakPolarHBondContact CD1-OH 3.36Å; Y213-Y245 AromaticContact CE1-CE2 3.98Å; Y213-Y245 HydrophobicContact CE1-CE2 3.98Å; Y213-I381 HydrophobicContact CD2-CD1 3.7Å; Y213-I381 HydrophobicContact CE2-CD1 3.26Å; Y213-I381 HydrophobicContact CG-CD1 4.49Å
214G97Very high96.3Very high0 Ų044.4 Ų44.40%022%0.218CC..Hα-helixtrans-66.3-32.4-177.400000114A210 L211 S212 R217 R218 F435A210-G214 PolarHBondContact O-N 3.14Å; L211-G214 PolarHBondContact O-N 3.36Å; S212-G214 PolarHBondContact O-N 3.39Å; G214-R217 CarbonylContact O-C 3.57Å; G214-R218 WeakPolarHBondContact O-CA 3.42Å; G214-R218 PolarHBondContact O-N 3.42Å; G214-F435 VanDerWaalsContact C-CE2 3.46Å; G214-F435 WeakPolarHBondContact O-CE2 3.34Å
215V95.4Very high96.2Very high24 Ų2446.3 Ų46.315%0.14523%0.234CC..Hα-helixtrans-66.5-46177.6160.80000111.6L211 S212 Y213 R218 Y421 F435L211-V215 HydrophobicContact CD1-CG2 3.88Å; L211-V215 HydrophobicContact CG-CG2 4.35Å; L211-V215 VanDerWaalsContact O-CB 3.31Å; L211-V215 WeakPolarHBondContact O-CB 3.47Å; L211-V215 WeakPolarHBondContact O-CG2 3.49Å; L211-V215 PolarHBondContact O-N 3.05Å; S212-V215 PolarHBondContact O-N 2.66Å; Y213-V215 PolarHBondContact O-N 2.89Å; V215-R218 WeakPolarHBondContact O-CB 3.29Å; V215-Y421 HydrophobicContact CB-CD2 4.38Å; V215-Y421 HydrophobicContact CB-CE2 4.21Å; V215-Y421 HydrophobicContact CG1-CD2 3.67Å; V215-Y421 HydrophobicContact CG1-CE2 3.41Å; V215-Y421 VanDerWaalsContact CG1-CE2 3.41Å; V215-Y421 HydrophobicContact CG1-CG 4.5Å; V215-Y421 HydrophobicContact CG2-CD1 3.85Å; V215-Y421 HydrophobicContact CG2-CD2 3.88Å; V215-Y421 HydrophobicContact CG2-CE1 3.65Å; V215-Y421 HydrophobicContact CG2-CE2 3.65Å; V215-Y421 HydrophobicContact CG2-CG 3.96Å; V215-F435 HydrophobicContact CG2-CD2 3.98Å; V215-F435 HydrophobicContact CG2-CE2 4.48Å; V215-F435 HydrophobicContact CG2-CG 4.38Å
216F92.5Very high96.3Very high154 Ų15447.2 Ų47.268%0.67524%0.237SC*.Hα-helixtrans-70.6-34.9177-70.2-67.9000112S212 Y213 R218S212-F216 WeakPolarHBondContact O-CD2 3.23Å; S212-F216 PolarHBondContact O-N 3.12Å; Y213-F216 PolarHBondContact O-N 3.01Å; F216-R218 PolarHBondContact O-N 2.8Å
217R94.9Very high96.3Very high85 Ų8548.2 Ų48.232%0.32124%0.243SC..THydrogen-bonded Turntrans-92.220178-68.8173.9170.8-121-21.3114.6Y213 G214 K219 D220 N408Y213-R217 WeakPolarHBondContact O-CB 3.47Å; Y213-R217 PolarHBondContact O-N 2.9Å; Y213-R217 PolarHBondContact OH-NH1 3.08Å; G214-R217 CarbonylContact O-C 3.57Å; R217-K219 PolarHBondContact O-N 2.67Å; R217-D220 WeakPolarHBondContact CA-OD2 3.28Å; R217-D220 VanDerWaalsContact CB-OD2 3.31Å; R217-D220 WeakPolarHBondContact CB-OD2 3.43Å; R217-D220 WeakPolarHBondContact CG-OD2 3.4Å; R217-D220 WeakPolarHBondContact O-CB 3.46Å; R217-D220 PolarHBondContact O-N 2.66Å; R217-N408 PolarHBondContact NH1-ND2 2.8Å; R217-N408 PolarHBondContact NH2-ND2 2.81Å
218R94.5Very high96.3Very high50 Ų5048.4 Ų48.419%0.18924%0.244CC..THydrogen-bonded Turntrans-53.9-25.9-176.3166.8178.7-97.3119.6-11.5114.7G214 V215 F216 P257 Y421 K433 P434G214-R218 WeakPolarHBondContact O-CA 3.42Å; G214-R218 PolarHBondContact O-N 3.42Å; V215-R218 WeakPolarHBondContact O-CB 3.29Å; F216-R218 PolarHBondContact O-N 2.8Å; R218-P257 HydrophobicContact CG-CG 4.29Å; R218-Y421 PolarHBondContact NH1-OH 3.42Å; R218-Y421 VanDerWaalsContact NH1-OH 3.08Å; R218-Y421 PolarHBondContact NH2-OH 2.95Å; R218-K433 VanDerWaalsContact NH2-C 3.34Å; R218-K433 PolarHBondContact NH2-O 3.1Å; R218-P434 VanDerWaalsContact NH2-C 3.3Å; R218-P434 PolarHBondContact NH2-O 2.85Å
219K93.4Very high96.3Very high202 Ų20248.4 Ų48.488%0.87824%0.244SC*.THydrogen-bonded Turntrans-76.9-22.6178.6-66.4-177.8-177.8175.30113.3R217R217-K219 PolarHBondContact O-N 2.67Å
220D94.1Very high96.3Very high90 Ų9048.3 Ų48.348%0.48124%0.243SC..THydrogen-bonded Turntrans-92.7-23.1-170-41.8-36.7000110.8R217 N222 Q226R217-D220 WeakPolarHBondContact CA-OD2 3.28Å; R217-D220 VanDerWaalsContact CB-OD2 3.31Å; R217-D220 WeakPolarHBondContact CB-OD2 3.43Å; R217-D220 WeakPolarHBondContact CG-OD2 3.4Å; R217-D220 WeakPolarHBondContact O-CB 3.46Å; R217-D220 PolarHBondContact O-N 2.66Å; D220-N222 PolarHBondContact O-N 3.31Å; D220-N222 PolarHBondContact O-ND2 3.12Å; D220-Q226 PolarHBondContact O-NE2 3.13Å; D220-Q226 VanDerWaalsContact O-NE2 3.1Å
221I95.9Very high96.3Very high11 Ų1148.3 Ų48.36%0.05624%0.243CC..  trans-68.2117.3172.3-54.4174.5000109.2Y245 M247 P257 F435I221-Y245 HydrophobicContact CD1-CD1 3.85Å; I221-Y245 HydrophobicContact CD1-CG 4.35Å; I221-M247 HydrophobicContact CG2-CG 4.21Å; I221-M247 HydrophobicContact CG2-SD 4.35Å; I221-M247 VanDerWaalsContact O-CG 3.32Å; I221-M247 WeakPolarHBondContact O-CG 3.29Å; I221-P257 HydrophobicContact CB-CB 4.47Å; I221-P257 HydrophobicContact CD1-CB 3.96Å; I221-P257 HydrophobicContact CG2-CB 4.17Å; I221-F435 HydrophobicContact CD1-CE2 3.88Å; I221-F435 HydrophobicContact CD1-CZ 3.72Å
222N94.8Very high96.3Very high62 Ų6249.6 Ų49.633%0.33225%0.25SS..  trans-123.7-166.7-178.967.289.7000110.7D220 T224 Q226 Q246 M247D220-N222 PolarHBondContact O-N 3.31Å; D220-N222 PolarHBondContact O-ND2 3.12Å; N222-T224 VanDerWaalsContact C-N 3.25Å; N222-T224 PolarHBondContact O-N 3.38Å; N222-T224 WeakPolarHBondContact OD1-CB 3.38Å; N222-T224 PolarHBondContact OD1-N 3.05Å; N222-T224 PolarHBondContact OD1-OG1 3.31Å; N222-Q226 PolarHBondContact ND2-NE2 3.29Å; N222-Q246 CarbonylContact O-C 3.59Å; N222-Q246 WeakPolarHBondContact O-CA 3.25Å; N222-M247 PolarHBondContact O-N 3.16Å
223T94.1Very high96.4Very high108 Ų10849.3 Ų49.366%0.66325%0.248SC*.SBendtrans-75.3-11.3-179.646.80000114.2M247 M255T223-M247 HydrophobicContact CG2-CB 4.29Å; T223-M255 HydrophobicContact CG2-CE 3.87Å
224T95.5Very high96.3Very high88 Ų8848.9 Ų48.954%0.5425%0.251SS..SBendtrans-80.4139.2172.5-41.10000109.5N222 Q226N222-T224 VanDerWaalsContact C-N 3.25Å; N222-T224 PolarHBondContact O-N 3.38Å; N222-T224 WeakPolarHBondContact OD1-CB 3.38Å; N222-T224 PolarHBondContact OD1-N 3.05Å; N222-T224 PolarHBondContact OD1-OG1 3.31Å; T224-Q226 PolarHBondContact O-N 2.89Å
225A96.4Very high96.3Very high42 Ų4249.4 Ų49.435%0.34725%0.254SS..  trans-72.6113.9175.600000110.6T244A225-T244 HydrophobicContact CB-CG2 3.63Å
226Q97.9Very high96.3Very high40 Ų4048.3 Ų48.319%0.18725%0.248CC..EExtended strand (participates in β ladder)trans-99.4116.2176.3-74.2168-32.100109.3D220 N222 T224 T244 Y245 E378D220-Q226 PolarHBondContact O-NE2 3.13Å; D220-Q226 VanDerWaalsContact O-NE2 3.1Å; N222-Q226 PolarHBondContact ND2-NE2 3.29Å; T224-Q226 PolarHBondContact O-N 2.89Å; Q226-T244 CarbonylContact O-C 3.57Å; Q226-T244 WeakPolarHBondContact O-CA 3.15Å; Q226-Y245 PolarHBondContact N-O 3.28Å; Q226-Y245 PolarHBondContact O-N 3.04Å; Q226-E378 WeakPolarHBondContact CA-OE2 3.44Å; Q226-E378 VanDerWaalsContact CB-OE2 3.24Å; Q226-E378 WeakPolarHBondContact CB-OE2 3.39Å; Q226-E378 WeakPolarHBondContact CG-OE2 3.48Å
227N98.3Very high96.5Very high22 Ų2241.7 Ų41.712%0.11822%0.221CC..EExtended strand (participates in β ladder)trans-104.3115.1-175.7-54.2-53.1000111.5V243 T244 M372 E376 I377 E378N227-V243 WeakPolarHBondContact CA-O 3.25Å; N227-T244 PolarHBondContact OD1-OG1 3.13Å; N227-M372 HydrophobicContact CB-CE 3.9Å; N227-M372 WeakPolarHBondContact ND2-CE 3.47Å; N227-E376 WeakPolarHBondContact CB-O 3.23Å; N227-E376 PolarHBondContact ND2-O 3.43Å; N227-E376 VanDerWaalsContact ND2-O 3.15Å; N227-I377 HydrophobicContact CB-CD1 4.38Å; N227-E378 PolarHBondContact O-N 3.34Å
228I98.4Very high96.7Very high6 Ų637.6 Ų37.63%0.03121%0.205CC..EExtended strand (participates in β ladder)trans-116.1134.6-177.6-51.4-63.6000108.9Y213 F230 V243 Y245 E378 Q379 I381Y213-I228 HydrophobicContact CE1-CG1 4.21Å; I228-F230 HydrophobicContact CB-CE2 4.05Å; I228-F230 HydrophobicContact CG2-CD2 4.25Å; I228-F230 HydrophobicContact CG2-CE2 3.65Å; I228-F230 HydrophobicContact CG2-CZ 3.8Å; I228-V243 PolarHBondContact N-O 2.86Å; I228-V243 PolarHBondContact O-N 3.43Å; I228-Y245 HydrophobicContact CB-CD2 4.42Å; I228-Y245 HydrophobicContact CB-CE2 3.96Å; I228-Y245 HydrophobicContact CG1-CD2 3.83Å; I228-Y245 HydrophobicContact CG1-CE2 3.75Å; I228-E378 HydrophobicContact CD1-CB 4.22Å; I228-Q379 HydrophobicContact CD1-CB 3.99Å; I228-I381 HydrophobicContact CG2-CD1 3.52Å; I228-I381 HydrophobicContact CG2-CG1 3.94Å
229M98.8Very high96.9Very high0 Ų035.3 Ų35.30%020%0.197CC..EExtended strand (participates in β ladder)trans-101.9121175.2178.4-178.3-73.900109.5C240 T241 I242 V363 L367 I377 Q379 V380 I381 V400M229-C240 VanDerWaalsContact CG-SG 3.53Å; M229-C240 VanDerWaalsContact SD-SG 3.65Å; M229-T241 WeakPolarHBondContact CA-O 3.02Å; M229-I242 HydrophobicContact CB-CG1 4.45Å; M229-I242 HydrophobicContact CE-CD1 3.9Å; M229-I242 HydrophobicContact CE-CG1 3.84Å; M229-I242 HydrophobicContact CG-CG1 4.38Å; M229-V363 HydrophobicContact CE-CG1 3.92Å; M229-V363 HydrophobicContact SD-CG1 3.97Å; M229-V363 HydrophobicContact SD-CG2 4.37Å; M229-L367 HydrophobicContact CE-CD2 4.07Å; M229-L367 HydrophobicContact CE-CG 4.08Å; M229-I377 HydrophobicContact CB-CG2 3.73Å; M229-I377 HydrophobicContact CE-CD1 4.42Å; M229-I377 HydrophobicContact CE-CG1 4.17Å; M229-Q379 PolarHBondContact N-O 3.01Å; M229-V380 HydrophobicContact CB-CG2 4.19Å; M229-V380 HydrophobicContact CG-CG1 4.28Å; M229-V380 HydrophobicContact CG-CG2 4.5Å; M229-V380 CarbonylContact O-C 3.51Å; M229-V380 WeakPolarHBondContact O-CA 3.47Å; M229-V380 HydrophobicContact SD-CG1 4.14Å; M229-V380 HydrophobicContact SD-CG2 3.97Å; M229-I381 PolarHBondContact O-N 2.74Å; M229-V400 HydrophobicContact SD-CG1 4.5Å
230F98.7Very high97.2Very high0 Ų025.7 Ų25.70%016%0.155CC..EExtended strand (participates in β ladder)trans-96.9124.4170.8-64.8-92.1000108.7T209 A210 Y213 I228 C240 T241 V243 Y245 I381 V383T209-F230 HydrophobicContact CG2-CD1 3.87Å; T209-F230 HydrophobicContact CG2-CE1 4.18Å; A210-F230 HydrophobicContact CB-CD2 4.19Å; A210-F230 HydrophobicContact CB-CE2 3.82Å; A210-F230 HydrophobicContact CB-CZ 4.16Å; Y213-F230 AromaticContact CD1-CZ 3.94Å; Y213-F230 HydrophobicContact CD1-CZ 3.94Å; Y213-F230 HydrophobicContact CD2-CE1 4.4Å; Y213-F230 HydrophobicContact CD2-CZ 4.35Å; Y213-F230 HydrophobicContact CG-CE1 4.16Å; Y213-F230 AromaticContact CG-CZ 3.8Å; Y213-F230 HydrophobicContact CG-CZ 3.8Å; I228-F230 HydrophobicContact CB-CE2 4.05Å; I228-F230 HydrophobicContact CG2-CD2 4.25Å; I228-F230 HydrophobicContact CG2-CE2 3.65Å; I228-F230 HydrophobicContact CG2-CZ 3.8Å; F230-C240 CarbonylContact O-C 3.54Å; F230-C240 WeakPolarHBondContact O-CA 3.44Å; F230-T241 PolarHBondContact N-O 3.09Å; F230-T241 PolarHBondContact O-N 3.07Å; F230-V243 HydrophobicContact CD2-CB 4.45Å; F230-V243 HydrophobicContact CD2-CG2 3.77Å; F230-V243 HydrophobicContact CE2-CB 4.21Å; F230-V243 HydrophobicContact CE2-CG2 3.95Å; F230-Y245 HydrophobicContact CE2-CE2 4.2Å; F230-Y245 WeakPolarHBondContact CE2-OH 3.35Å; F230-Y245 HydrophobicContact CZ-CE2 4.45Å; F230-Y245 VanDerWaalsContact CZ-OH 3.31Å; F230-Y245 WeakPolarHBondContact CZ-OH 3.29Å; F230-I381 HydrophobicContact CD1-CB 4.08Å; F230-I381 HydrophobicContact CD1-CG2 4.18Å; F230-I381 HydrophobicContact CE1-CB 4.21Å; F230-I381 HydrophobicContact CE1-CD1 3.91Å; F230-I381 HydrophobicContact CE1-CG2 4.21Å; F230-I381 HydrophobicContact CZ-CD1 4.15Å; F230-V383 HydrophobicContact CB-CG2 4.38Å; F230-V383 HydrophobicContact CD1-CG2 4.18Å
231Y98.7Very high97.4Very high0 Ų021.5 Ų21.50%013%0.133CC..EExtended strand (participates in β ladder)trans-115.4103.1176.8-173.2-82.6000109M233 T238 C240 V359 P362 V363 I381 V383 T387 L396Y231-M233 HydrophobicContact CE1-CB 4Å; Y231-T238 HydrophobicContact CE1-CG2 3.96Å; Y231-T238 HydrophobicContact CE2-CG2 4Å; Y231-T238 WeakPolarHBondContact OH-CG2 3.4Å; Y231-C240 HydrophobicContact CD2-CB 4.04Å; Y231-V359 WeakPolarHBondContact OH-CG1 2.91Å; Y231-V359 PolarHBondContact OH-O 3.15Å; Y231-P362 HydrophobicContact CE2-CB 4.36Å; Y231-V363 HydrophobicContact CD2-CG2 3.8Å; Y231-V363 HydrophobicContact CE2-CG2 3.85Å; Y231-I381 PolarHBondContact N-O 3.09Å; Y231-V383 PolarHBondContact O-N 3.35Å; Y231-T387 HydrophobicContact CD1-CG2 3.98Å; Y231-T387 HydrophobicContact CE1-CG2 4.25Å; Y231-L396 HydrophobicContact CD1-CD1 4.41Å; Y231-L396 HydrophobicContact CD1-CD2 3.48Å; Y231-L396 VanDerWaalsContact CD1-CD2 3.48Å; Y231-L396 HydrophobicContact CD2-CD1 3.71Å; Y231-L396 HydrophobicContact CD2-CD2 4.19Å; Y231-L396 HydrophobicContact CE1-CD1 4.41Å; Y231-L396 HydrophobicContact CE1-CD2 3.83Å; Y231-L396 HydrophobicContact CE2-CD1 3.71Å; Y231-L396 HydrophobicContact CE2-CD2 4.49Å; Y231-L396 HydrophobicContact CG-CD1 4.08Å; Y231-L396 HydrophobicContact CG-CD2 3.68Å
232D98.4Very high97.5Very high28 Ų2821 Ų2115%0.1513%0.13CC..EExtended strand (participates in β ladder)trans-94.2122.2173.6-166.1-38.5000109.6G234 T238 V239 V383 G384D232-G234 PolarHBondContact OD1-N 3.41Å; D232-T238 CarbonylContact O-C 3.25Å; D232-T238 VanDerWaalsContact O-CA 3.27Å; D232-T238 WeakPolarHBondContact O-CA 3.26Å; D232-T238 WeakPolarHBondContact O-CG2 3.44Å; D232-V239 PolarHBondContact N-O 3.34Å; D232-V239 PolarHBondContact O-N 2.93Å; D232-V383 WeakPolarHBondContact CA-O 3.48Å; D232-V383 HydrophobicContact CB-CB 3.83Å; D232-V383 HydrophobicContact CB-CG1 4.21Å; D232-V383 VanDerWaalsContact OD2-CG1 3.32Å; D232-V383 WeakPolarHBondContact OD2-CG1 3.2Å; D232-G384 WeakPolarHBondContact OD1-CA 3.43Å
233M98.4Very high97.7Very high0 Ų018 Ų180%011%0.114CC..EExtended strand (participates in β ladder)trans-118.195.8162.2-169175.117500109.2Y231 T238 L270 M275 V383 G384 G385 A386 T387 V392Y231-M233 HydrophobicContact CE1-CB 4Å; M233-T238 HydrophobicContact CB-CG2 4.33Å; M233-T238 HydrophobicContact CG-CG2 4.44Å; M233-T238 WeakPolarHBondContact CG-OG1 3.2Å; M233-L270 HydrophobicContact CE-CD1 3.78Å; M233-L270 HydrophobicContact CE-CG 3.82Å; M233-M275 HydrophobicContact CE-CE 3.45Å; M233-M275 VanDerWaalsContact CE-CE 3.45Å; M233-V383 PolarHBondContact N-O 2.97Å; M233-G384 CarbonylContact O-C 3.48Å; M233-G384 VanDerWaalsContact O-C 3.26Å; M233-G385 PolarHBondContact O-N 3.14Å; M233-A386 HydrophobicContact CB-CB 4.5Å; M233-A386 HydrophobicContact CE-CB 4.34Å; M233-A386 HydrophobicContact CG-CB 3.95Å; M233-A386 WeakPolarHBondContact O-CB 3.27Å; M233-A386 PolarHBondContact O-N 3.29Å; M233-A386 HydrophobicContact SD-CB 4.34Å; M233-T387 HydrophobicContact CB-CG2 3.65Å; M233-V392 HydrophobicContact CE-CG2 4.47Å; M233-V392 HydrophobicContact SD-CB 4.48Å; M233-V392 HydrophobicContact SD-CG1 3.66Å; M233-V392 HydrophobicContact SD-CG2 3.92Å
234G96.6Very high97.9Very high15 Ų1512.9 Ų12.916%0.1558%0.083CC..  trans-81-158.117900000112.8D232 S237 G271 G272 A386D232-G234 PolarHBondContact OD1-N 3.41Å; G234-S237 PolarHBondContact N-O 3.44Å; G234-S237 VanDerWaalsContact N-O 3.07Å; G234-G271 WeakPolarHBondContact O-CA 3.45Å; G234-G272 PolarHBondContact O-N 3.01Å; G234-A386 WeakPolarHBondContact O-CB 3.39Å
235S96.6Very high98.1Very high10 Ų108.8 Ų8.87%0.076%0.057CC..SBendtrans-85.4-38.5176.157.10000113.1E43 Y99 G271 G272 L273E43-S235 WeakPolarHBondContact CB-OG 3.45Å; E43-S235 PolarHBondContact N-OG 3.04Å; Y99-S235 WeakPolarHBondContact OH-CB 3.39Å; S235-G271 CarbonylContact O-C 3.22Å; S235-G271 VanDerWaalsContact O-C 3.25Å; S235-G271 WeakPolarHBondContact O-CA 3.4Å; S235-G272 PolarHBondContact O-N 3.45Å; S235-G272 VanDerWaalsContact O-N 3.13Å; S235-L273 VanDerWaalsContact O-CB 3.26Å; S235-L273 WeakPolarHBondContact O-CB 3.5Å; S235-L273 PolarHBondContact O-N 2.95Å
236G95.5Very high98.1Very high2 Ų28.9 Ų8.92%0.0215%0.05CC..SBendtrans-92.8-30.4-179.200000115.9T269G236-T269 CarbonylContact O-C 3.58Å
237S97.7Very high98.1Very high14 Ų149.3 Ų9.310%0.0985%0.053CC..  trans-156.9166.3-167.4540000112.8F179 G234 D267 L270F179-S237 WeakPolarHBondContact CZ-OG 3.28Å; G234-S237 PolarHBondContact N-O 3.44Å; G234-S237 VanDerWaalsContact N-O 3.07Å; S237-D267 WeakPolarHBondContact CA-O 3.42Å; S237-D267 WeakPolarHBondContact CB-O 3.43Å; S237-L270 CarbonylContact C-O 3.43Å; S237-L270 WeakPolarHBondContact CA-O 3.44Å
238T98.6Very high97.9Very high0 Ų09.7 Ų9.70%06%0.056CC..EExtended strand (participates in β ladder)trans-119.7136.5175.5-56.10000110.2Y231 D232 M233 F266 D267 L270 P362Y231-T238 HydrophobicContact CE1-CG2 3.96Å; Y231-T238 HydrophobicContact CE2-CG2 4Å; Y231-T238 WeakPolarHBondContact OH-CG2 3.4Å; D232-T238 CarbonylContact O-C 3.25Å; D232-T238 VanDerWaalsContact O-CA 3.27Å; D232-T238 WeakPolarHBondContact O-CA 3.26Å; D232-T238 WeakPolarHBondContact O-CG2 3.44Å; M233-T238 HydrophobicContact CB-CG2 4.33Å; M233-T238 HydrophobicContact CG-CG2 4.44Å; M233-T238 WeakPolarHBondContact CG-OG1 3.2Å; T238-F266 CarbonylContact O-C 3.46Å; T238-F266 VanDerWaalsContact O-CA 3.24Å; T238-F266 WeakPolarHBondContact O-CA 3.47Å; T238-F266 WeakPolarHBondContact O-CB 3.24Å; T238-D267 PolarHBondContact N-O 2.89Å; T238-D267 PolarHBondContact O-N 2.99Å; T238-L270 PolarHBondContact N-O 2.65Å; T238-L270 WeakPolarHBondContact OG1-CG 3.49Å; T238-L270 PolarHBondContact OG1-O 2.86Å; T238-P362 HydrophobicContact CG2-CB 4.28Å; T238-P362 HydrophobicContact CG2-CG 3.81Å
239V98.5Very high97.6Very high2 Ų218.1 Ų18.11%0.0129%0.093CC..EExtended strand (participates in β ladder)trans-136.1124.8178.5-175.90000110.3V178 F179 N206 D232 F266V178-V239 HydrophobicContact CB-CG1 4.44Å; V178-V239 HydrophobicContact CG1-CG1 3.43Å; V178-V239 VanDerWaalsContact CG1-CG1 3.43Å; V178-V239 HydrophobicContact CG1-CG2 4.31Å; F179-V239 HydrophobicContact CD1-CG2 4.04Å; F179-V239 HydrophobicContact CE1-CG2 3.85Å; N206-V239 WeakPolarHBondContact ND2-CG1 3.35Å; N206-V239 PolarHBondContact ND2-O 3.37Å; N206-V239 VanDerWaalsContact ND2-O 3.12Å; D232-V239 PolarHBondContact N-O 3.34Å; D232-V239 PolarHBondContact O-N 2.93Å; V239-F266 HydrophobicContact CG2-CB 4.33Å
240C98.7Very high97Very high0 Ų019.9 Ų19.90%010%0.103CC..EExtended strand (participates in β ladder)trans-108.4132170.9-175.70000109.9M229 F230 Y231 V264 G265 P362 A366M229-C240 VanDerWaalsContact CG-SG 3.53Å; M229-C240 VanDerWaalsContact SD-SG 3.65Å; F230-C240 CarbonylContact O-C 3.54Å; F230-C240 WeakPolarHBondContact O-CA 3.44Å; Y231-C240 HydrophobicContact CD2-CB 4.04Å; C240-V264 WeakPolarHBondContact O-CA 3.28Å; C240-G265 PolarHBondContact N-O 3.13Å; C240-G265 PolarHBondContact O-N 2.86Å; C240-P362 HydrophobicContact CB-CB 3.71Å; C240-P362 WeakPolarHBondContact CB-O 2.99Å; C240-A366 HydrophobicContact CB-CB 4.07Å
241T98.8Very high96.3Very high1 Ų129.8 Ų29.81%0.00615%0.146CC..EExtended strand (participates in β ladder)trans-139.4121.2-173.7-54.60000110.7N206 M229 F230 V243 I261 G263 V264N206-T241 HydrophobicContact CB-CG2 4.21Å; N206-T241 WeakPolarHBondContact CB-OG1 3.34Å; N206-T241 PolarHBondContact ND2-OG1 3.16Å; M229-T241 WeakPolarHBondContact CA-O 3.02Å; F230-T241 PolarHBondContact N-O 3.09Å; F230-T241 PolarHBondContact O-N 3.07Å; T241-V243 HydrophobicContact CG2-CG2 4.08Å; T241-I261 HydrophobicContact CG2-CD1 3.93Å; T241-I261 HydrophobicContact CG2-CG2 3.77Å; T241-G263 WeakPolarHBondContact CA-O 3.43Å; T241-V264 HydrophobicContact CG2-CG2 4.43Å
242I98.9Very high95.1Very high0 Ų038.9 Ų38.90%019%0.189CC..EExtended strand (participates in β ladder)trans-94.3130.2176.6-61168.2000108.8M229 R262 G263 A366 L367 A370 M372 I377M229-I242 HydrophobicContact CB-CG1 4.45Å; M229-I242 HydrophobicContact CE-CD1 3.9Å; M229-I242 HydrophobicContact CE-CG1 3.84Å; M229-I242 HydrophobicContact CG-CG1 4.38Å; I242-R262 HydrophobicContact CB-CB 4.41Å; I242-R262 HydrophobicContact CG2-CB 4.13Å; I242-R262 PolarHBondContact O-N 3.37Å; I242-G263 PolarHBondContact N-O 3.07Å; I242-A366 HydrophobicContact CD1-CB 4.03Å; I242-A366 HydrophobicContact CG1-CB 4.16Å; I242-L367 HydrophobicContact CD1-CD2 3.78Å; I242-L367 HydrophobicContact CD1-CG 4.12Å; I242-A370 HydrophobicContact CD1-CB 3.99Å; I242-M372 HydrophobicContact CG2-CE 4.45Å; I242-M372 HydrophobicContact CG2-SD 3.98Å; I242-I377 HydrophobicContact CD1-CD1 4.06Å; I242-I377 HydrophobicContact CG1-CD1 4.17Å; I242-I377 HydrophobicContact CG2-CD1 3.74Å
243V98.8Very high93.9Very high0 Ų039.5 Ų39.50%020%0.198CC..EExtended strand (participates in β ladder)trans-130123.2-173.3-171.90000109.8A210 N227 I228 F230 T241 Y245 L259 Q260 I261A210-V243 HydrophobicContact CB-CG1 4.33Å; A210-V243 HydrophobicContact CB-CG2 4.03Å; N227-V243 WeakPolarHBondContact CA-O 3.25Å; I228-V243 PolarHBondContact N-O 2.86Å; I228-V243 PolarHBondContact O-N 3.43Å; F230-V243 HydrophobicContact CD2-CB 4.45Å; F230-V243 HydrophobicContact CD2-CG2 3.77Å; F230-V243 HydrophobicContact CE2-CB 4.21Å; F230-V243 HydrophobicContact CE2-CG2 3.95Å; T241-V243 HydrophobicContact CG2-CG2 4.08Å; V243-Y245 HydrophobicContact CB-CE2 4.19Å; V243-Y245 HydrophobicContact CG1-CD2 4.37Å; V243-Y245 HydrophobicContact CG1-CE1 4.32Å; V243-Y245 HydrophobicContact CG1-CE2 3.89Å; V243-L259 HydrophobicContact CG1-CB 3.84Å; V243-L259 HydrophobicContact CG1-CD1 4.18Å; V243-Q260 WeakPolarHBondContact CA-O 3.47Å; V243-I261 HydrophobicContact CB-CD1 4.5Å; V243-I261 HydrophobicContact CG1-CD1 4.27Å; V243-I261 HydrophobicContact CG2-CD1 3.63Å
244T98.6Very high93.3Very high0 Ų041 Ų410%021%0.214CC..EExtended strand (participates in β ladder)trans-86.9126166.4-57.80000109.5A225 Q226 N227 Q246 L259 Q260 R262A225-T244 HydrophobicContact CB-CG2 3.63Å; Q226-T244 CarbonylContact O-C 3.57Å; Q226-T244 WeakPolarHBondContact O-CA 3.15Å; N227-T244 PolarHBondContact OD1-OG1 3.13Å; T244-Q246 HydrophobicContact CG2-CG 4.29Å; T244-L259 CarbonylContact O-C 3.53Å; T244-L259 WeakPolarHBondContact O-CA 3.24Å; T244-Q260 PolarHBondContact N-O 2.95Å; T244-Q260 PolarHBondContact O-N 3.11Å; T244-R262 VanDerWaalsContact OG1-CG 3.26Å; T244-R262 WeakPolarHBondContact OG1-CG 3.21Å; T244-R262 PolarHBondContact OG1-NE 2.96Å
245Y98.6Very high93.1Very high2 Ų244.7 Ų44.71%0.00823%0.228CC..EExtended strand (participates in β ladder)trans-99137.4163-60.3-87.5000110.4A210 Y213 I221 Q226 I228 F230 V243 Q258 L259 F435A210-Y245 VanDerWaalsContact CA-OH 3.25Å; A210-Y245 WeakPolarHBondContact CA-OH 3.27Å; A210-Y245 VanDerWaalsContact CB-OH 3.3Å; A210-Y245 WeakPolarHBondContact CB-OH 3.39Å; A210-Y245 PolarHBondContact O-OH 3.29Å; Y213-Y245 HydrophobicContact CD1-CE1 4.35Å; Y213-Y245 AromaticContact CD1-CE2 3.86Å; Y213-Y245 HydrophobicContact CD1-CE2 3.86Å; Y213-Y245 AromaticContact CD1-CZ 3.65Å; Y213-Y245 WeakPolarHBondContact CD1-OH 3.36Å; Y213-Y245 AromaticContact CE1-CE2 3.98Å; Y213-Y245 HydrophobicContact CE1-CE2 3.98Å; I221-Y245 HydrophobicContact CD1-CD1 3.85Å; I221-Y245 HydrophobicContact CD1-CG 4.35Å; Q226-Y245 PolarHBondContact N-O 3.28Å; Q226-Y245 PolarHBondContact O-N 3.04Å; I228-Y245 HydrophobicContact CB-CD2 4.42Å; I228-Y245 HydrophobicContact CB-CE2 3.96Å; I228-Y245 HydrophobicContact CG1-CD2 3.83Å; I228-Y245 HydrophobicContact CG1-CE2 3.75Å; F230-Y245 HydrophobicContact CE2-CE2 4.2Å; F230-Y245 WeakPolarHBondContact CE2-OH 3.35Å; F230-Y245 HydrophobicContact CZ-CE2 4.45Å; F230-Y245 VanDerWaalsContact CZ-OH 3.31Å; F230-Y245 WeakPolarHBondContact CZ-OH 3.29Å; V243-Y245 HydrophobicContact CB-CE2 4.19Å; V243-Y245 HydrophobicContact CG1-CD2 4.37Å; V243-Y245 HydrophobicContact CG1-CE1 4.32Å; V243-Y245 HydrophobicContact CG1-CE2 3.89Å; Y245-Q258 WeakPolarHBondContact CA-O 3.49Å; Y245-L259 HydrophobicContact CD1-CB 3.75Å; Y245-L259 HydrophobicContact CE1-CB 3.58Å; Y245-L259 HydrophobicContact CE1-CD2 4.4Å; Y245-F435 HydrophobicContact CD1-CZ 4.3Å; Y245-F435 HydrophobicContact CE1-CZ 4.47Å
246Q97.6Very high93.1Very high44 Ų4445.9 Ų45.921%0.20623%0.233CC..EExtended strand (participates in β ladder)trans-163.5153.7177.652.7176.813.500111.6N222 T244 V248 Q258N222-Q246 CarbonylContact O-C 3.59Å; N222-Q246 WeakPolarHBondContact O-CA 3.25Å; T244-Q246 HydrophobicContact CG2-CG 4.29Å; Q246-V248 HydrophobicContact CG-CG1 3.89Å; Q246-Q258 HydrophobicContact CG-CB 4.49Å; Q246-Q258 PolarHBondContact N-O 2.98Å; Q246-Q258 VanDerWaalsContact N-O 3.11Å; Q246-Q258 WeakPolarHBondContact O-CB 3.35Å; Q246-Q258 PolarHBondContact O-N 2.85Å
247M96.8Very high93.1Very high50 Ų5046 Ų4625%0.24623%0.233CC..EExtended strand (participates in β ladder)trans-83.4117.9171.1-70.6-65-67.700110.7I221 N222 T223 M255 P257I221-M247 HydrophobicContact CG2-CG 4.21Å; I221-M247 HydrophobicContact CG2-SD 4.35Å; I221-M247 VanDerWaalsContact O-CG 3.32Å; I221-M247 WeakPolarHBondContact O-CG 3.29Å; N222-M247 PolarHBondContact O-N 3.16Å; T223-M247 HydrophobicContact CG2-CB 4.29Å; M247-M255 HydrophobicContact CB-CE 4.01Å; M247-M255 HydrophobicContact CE-CB 4.03Å; M247-M255 WeakPolarHBondContact O-CE 3.46Å; M247-P257 VanDerWaalsContact SD-CA 3.54Å; M247-P257 HydrophobicContact SD-CB 3.83Å; M247-P257 HydrophobicContact SD-CG 4.47Å; M247-P257 VanDerWaalsContact SD-N 3.37Å
248V94.8Very high93.1Very high29 Ų2946.3 Ų46.318%0.17623%0.233CC..EExtended strand (participates in β ladder)trans-116.6149-177.5-580000112.9Q246 T250 M255 Q256 Q258 V436Q246-V248 HydrophobicContact CG-CG1 3.89Å; V248-T250 HydrophobicContact CG2-CG2 4.5Å; V248-T250 PolarHBondContact O-N 2.97Å; V248-M255 WeakPolarHBondContact O-CA 3.38Å; V248-Q256 PolarHBondContact N-O 3.36Å; V248-Q256 PolarHBondContact O-N 2.92Å; V248-Q258 HydrophobicContact CB-CB 4.49Å; V248-Q258 HydrophobicContact CG1-CB 3.91Å; V248-Q258 HydrophobicContact CG1-CG 4.47Å; V248-Q258 HydrophobicContact CG2-CB 3.76Å; V248-V436 HydrophobicContact CG2-CG2 4.33Å
249K91.8Very high93.1Very high184 Ų18446.3 Ų46.380%0.823%0.233SC*.EExtended strand (participates in β ladder)trans-81.9103.9176.2-166.8176.5-177.4176.70111.2M255K249-M255 HydrophobicContact CB-SD 3.74Å; K249-M255 HydrophobicContact CG-SD 4.29Å
250T87.1Confident93.1Very high36 Ų3647.8 Ų47.822%0.22124%0.24CC..EExtended strand (participates in β ladder)trans-80.2157.5169.567.50000111.4V248 A253 G254 Q256 V436V248-T250 HydrophobicContact CG2-CG2 4.5Å; V248-T250 PolarHBondContact O-N 2.97Å; T250-A253 WeakPolarHBondContact OG1-CA 3.49Å; T250-A253 PolarHBondContact OG1-N 3.33Å; T250-A253 VanDerWaalsContact OG1-N 3.12Å; T250-G254 PolarHBondContact N-O 2.99Å; T250-G254 PolarHBondContact OG1-N 3.32Å; T250-G254 PolarHBondContact OG1-O 3.17Å; T250-Q256 HydrophobicContact CG2-CB 3.97Å; T250-Q256 HydrophobicContact CG2-CG 4.04Å; T250-V436 HydrophobicContact CG2-CG2 3.76Å
251K82.3Confident93.1Very high209 Ų20947.9 Ų47.991%0.90924%0.24SC*.THydrogen-bonded Turntrans-72.9-36.5175.9-69.9-176.1178.9179.30112.9
252E74.3Confident93Very high190 Ų19052.2 Ų52.289%0.88826%0.256SS*.THydrogen-bonded Turntrans-95.3-29.2-169.8-68.6134.2-126.100113.8
253A72.4Confident93Very high42 Ų4252.2 Ų52.235%0.34726%0.256SS..THydrogen-bonded Turntrans-129.713.6-169.600000114.1T250 Q256 P434T250-A253 WeakPolarHBondContact OG1-CA 3.49Å; T250-A253 PolarHBondContact OG1-N 3.33Å; T250-A253 VanDerWaalsContact OG1-N 3.12Å; A253-Q256 HydrophobicContact CB-CG 3.82Å; A253-Q256 PolarHBondContact O-NE2 3.02Å; A253-P434 HydrophobicContact CB-CG 4.35Å
254G87Confident93Very high32 Ų3252.5 Ų52.533%0.3326%0.258SS..EExtended strand (participates in β ladder)trans66.3-142.6-179.100000112.8T250 Q256T250-G254 PolarHBondContact N-O 2.99Å; T250-G254 PolarHBondContact OG1-N 3.32Å; T250-G254 PolarHBondContact OG1-O 3.17Å; G254-Q256 PolarHBondContact O-N 3.19Å
255M92.7Very high93Very high92 Ų9252.5 Ų52.545%0.45326%0.258SS..EExtended strand (participates in β ladder)trans-71.7119.7177.7-64.9-62.7-75.900110.4T223 M247 V248 K249T223-M255 HydrophobicContact CG2-CE 3.87Å; M247-M255 HydrophobicContact CB-CE 4.01Å; M247-M255 HydrophobicContact CE-CB 4.03Å; M247-M255 WeakPolarHBondContact O-CE 3.46Å; V248-M255 WeakPolarHBondContact O-CA 3.38Å; K249-M255 HydrophobicContact CB-SD 3.74Å; K249-M255 HydrophobicContact CG-SD 4.29Å
256Q95Very high93Very high35 Ų3552.8 Ų52.816%0.16426%0.259CS..EExtended strand (participates in β ladder)trans-131.6149.6178.9-65.2-60.5-33.300110.4V248 T250 A253 G254 P434 V436V248-Q256 PolarHBondContact N-O 3.36Å; V248-Q256 PolarHBondContact O-N 2.92Å; T250-Q256 HydrophobicContact CG2-CB 3.97Å; T250-Q256 HydrophobicContact CG2-CG 4.04Å; A253-Q256 HydrophobicContact CB-CG 3.82Å; A253-Q256 PolarHBondContact O-NE2 3.02Å; G254-Q256 PolarHBondContact O-N 3.19Å; Q256-P434 HydrophobicContact CG-CB 4.24Å; Q256-P434 PolarHBondContact OE1-O 3.19Å; Q256-P434 VanDerWaalsContact OE1-O 3.11Å; Q256-V436 HydrophobicContact CB-CG2 4.27Å
257P96.9Very high93Very high4 Ų452 Ų523%0.02626%0.256CS..EExtended strand (participates in β ladder)trans-67139.6173.530.1-35.8000110R218 I221 M247 F435 V436R218-P257 HydrophobicContact CG-CG 4.29Å; I221-P257 HydrophobicContact CB-CB 4.47Å; I221-P257 HydrophobicContact CD1-CB 3.96Å; I221-P257 HydrophobicContact CG2-CB 4.17Å; M247-P257 VanDerWaalsContact SD-CA 3.54Å; M247-P257 HydrophobicContact SD-CB 3.83Å; M247-P257 HydrophobicContact SD-CG 4.47Å; M247-P257 VanDerWaalsContact SD-N 3.37Å; P257-F435 HydrophobicContact CB-CD2 4.03Å; P257-F435 HydrophobicContact CB-CE2 3.65Å; P257-F435 HydrophobicContact CB-CZ 3.99Å; P257-F435 HydrophobicContact CG-CD2 3.54Å; P257-F435 HydrophobicContact CG-CE2 3.67Å; P257-F435 HydrophobicContact CG-CG 4.17Å; P257-F435 HydrophobicContact CG-CZ 4.41Å; P257-V436 PolarHBondContact O-N 3.48Å
258Q96.9Very high93Very high21 Ų2150.3 Ų50.310%0.09825%0.247CC..EExtended strand (participates in β ladder)trans-119.6143.5172.3172.9173.384.800109.4Y245 Q246 V248 Q260 V436Y245-Q258 WeakPolarHBondContact CA-O 3.49Å; Q246-Q258 HydrophobicContact CG-CB 4.49Å; Q246-Q258 PolarHBondContact N-O 2.98Å; Q246-Q258 VanDerWaalsContact N-O 3.11Å; Q246-Q258 WeakPolarHBondContact O-CB 3.35Å; Q246-Q258 PolarHBondContact O-N 2.85Å; V248-Q258 HydrophobicContact CB-CB 4.49Å; V248-Q258 HydrophobicContact CG1-CB 3.91Å; V248-Q258 HydrophobicContact CG1-CG 4.47Å; V248-Q258 HydrophobicContact CG2-CB 3.76Å; Q258-Q260 HydrophobicContact CG-CB 4.47Å; Q258-V436 CarbonylContact C-O 3.59Å; Q258-V436 VanDerWaalsContact CA-O 3.25Å; Q258-V436 WeakPolarHBondContact CA-O 3.47Å; Q258-V436 HydrophobicContact CB-CB 3.97Å; Q258-V436 HydrophobicContact CB-CG1 4.44Å; Q258-V436 HydrophobicContact CG-CB 4.23Å; Q258-V436 HydrophobicContact CG-CG1 4.22Å
259L98Very high93Very high0 Ų050.4 Ų50.40%025%0.248CC..EExtended strand (participates in β ladder)trans-108.9136.6152.275.689000108.1T207 A210 L211 V243 T244 Y245 I261 F435 V436 V437 R438T207-L259 HydrophobicContact CG2-CD1 4.17Å; A210-L259 HydrophobicContact CB-CD2 4.37Å; L211-L259 VanDerWaalsContact CA-CD2 3.46Å; L211-L259 HydrophobicContact CB-CD2 3.83Å; L211-L259 HydrophobicContact CD1-CD2 4.07Å; V243-L259 HydrophobicContact CG1-CB 3.84Å; V243-L259 HydrophobicContact CG1-CD1 4.18Å; T244-L259 CarbonylContact O-C 3.53Å; T244-L259 WeakPolarHBondContact O-CA 3.24Å; Y245-L259 HydrophobicContact CD1-CB 3.75Å; Y245-L259 HydrophobicContact CE1-CB 3.58Å; Y245-L259 HydrophobicContact CE1-CD2 4.4Å; L259-I261 HydrophobicContact CD1-CD1 3.99Å; L259-F435 HydrophobicContact CB-CE1 3.94Å; L259-F435 HydrophobicContact CD2-CD1 4.41Å; L259-F435 HydrophobicContact CD2-CE1 3.85Å; L259-F435 HydrophobicContact CG-CE1 4.08Å; L259-V436 PolarHBondContact N-O 2.88Å; L259-V437 HydrophobicContact CD1-CG1 4.29Å; L259-V437 HydrophobicContact CD2-CG2 4.43Å; L259-R438 PolarHBondContact O-N 2.83Å
260Q98.3Very high93.3Very high33 Ų3341.6 Ų41.615%0.15421%0.21CC..EExtended strand (participates in β ladder)trans-128.1124.2170.8177.8172.5-12.200109.6V243 T244 Q258 R438V243-Q260 WeakPolarHBondContact CA-O 3.47Å; T244-Q260 PolarHBondContact N-O 2.95Å; T244-Q260 PolarHBondContact O-N 3.11Å; Q258-Q260 HydrophobicContact CG-CB 4.47Å; Q260-R438 WeakPolarHBondContact CA-O 3.32Å; Q260-R438 HydrophobicContact CB-CB 4.11Å; Q260-R438 HydrophobicContact CG-CB 4.04Å
261I98.7Very high93.8Very high1 Ų139.9 Ų39.91%0.00520%0.199CC..EExtended strand (participates in β ladder)trans-68.4130.5170.5-50.6-54.5000108.5T207 T241 V243 L259 V264 R438 D439 A440T207-I261 HydrophobicContact CG2-CD1 4.37Å; T241-I261 HydrophobicContact CG2-CD1 3.93Å; T241-I261 HydrophobicContact CG2-CG2 3.77Å; V243-I261 HydrophobicContact CB-CD1 4.5Å; V243-I261 HydrophobicContact CG1-CD1 4.27Å; V243-I261 HydrophobicContact CG2-CD1 3.63Å; L259-I261 HydrophobicContact CD1-CD1 3.99Å; I261-V264 HydrophobicContact CG2-CG2 3.82Å; I261-R438 PolarHBondContact N-O 2.96Å; I261-D439 HydrophobicContact CG1-CB 4.5Å; I261-A440 HydrophobicContact CB-CB 3.8Å; I261-A440 HydrophobicContact CG2-CB 3.71Å
262R98.5Very high94.5Very high93 Ų9330 Ų3035%0.35116%0.156SC..EExtended strand (participates in β ladder)trans-107.9-47-176.9-67.2-57.5-160.2149.27.8113.1I242 T244 A370 M372I242-R262 HydrophobicContact CB-CB 4.41Å; I242-R262 HydrophobicContact CG2-CB 4.13Å; I242-R262 PolarHBondContact O-N 3.37Å; T244-R262 VanDerWaalsContact OG1-CG 3.26Å; T244-R262 WeakPolarHBondContact OG1-CG 3.21Å; T244-R262 PolarHBondContact OG1-NE 2.96Å; R262-A370 HydrophobicContact CB-CB 4.04Å; R262-A370 WeakPolarHBondContact O-CA 3.35Å; R262-M372 HydrophobicContact CB-SD 4.41Å
263G98.4Very high95.7Very high0 Ų021 Ų210%011%0.114CC..EExtended strand (participates in β ladder)trans-145.5149.4-176.600000111.2T241 I242 A366 S369T241-G263 WeakPolarHBondContact CA-O 3.43Å; I242-G263 PolarHBondContact N-O 3.07Å; G263-A366 WeakPolarHBondContact CA-O 3.42Å; G263-S369 WeakPolarHBondContact CA-OG 3.37Å
264V98.5Very high96.9Very high6 Ų620.8 Ų20.84%0.03611%0.106CC..EExtended strand (participates in β ladder)trans-139.3128.2-175.8176.60000109V178 C240 T241 I261 F266 S369 V442 M473V178-V264 HydrophobicContact CB-CG1 4.37Å; V178-V264 HydrophobicContact CG1-CG1 3.49Å; V178-V264 VanDerWaalsContact CG1-CG1 3.49Å; V178-V264 HydrophobicContact CG2-CG1 3.91Å; V178-V264 HydrophobicContact CG2-CG2 4.13Å; C240-V264 WeakPolarHBondContact O-CA 3.28Å; T241-V264 HydrophobicContact CG2-CG2 4.43Å; I261-V264 HydrophobicContact CG2-CG2 3.82Å; V264-F266 HydrophobicContact CG1-CD1 4.29Å; V264-S369 PolarHBondContact N-OG 3.01Å; V264-S369 PolarHBondContact O-OG 3.4Å; V264-S369 VanDerWaalsContact O-OG 3.07Å; V264-V442 HydrophobicContact CB-CG2 4.44Å; V264-V442 HydrophobicContact CG1-CG2 4.21Å; V264-V442 HydrophobicContact CG2-CG2 4.46Å; V264-M473 HydrophobicContact CB-CE 4.25Å; V264-M473 HydrophobicContact CB-SD 4.44Å; V264-M473 HydrophobicContact CG2-CE 4.22Å; V264-M473 HydrophobicContact CG2-SD 4.23Å
265G98.3Very high97.4Very high0 Ų019.2 Ų19.20%09%0.09CC..EExtended strand (participates in β ladder)trans-133.2150.6170.300000110.5C240 P362 Q365C240-G265 PolarHBondContact N-O 3.13Å; C240-G265 PolarHBondContact O-N 2.86Å; G265-P362 WeakPolarHBondContact CA-O 3.33Å; G265-Q365 VanDerWaalsContact CA-CB 3.47Å
266F98.2Very high97.7Very high8 Ų815.2 Ų15.24%0.0357%0.07CC..EExtended strand (participates in β ladder)trans-154.9162.6-175.858-99.8000113.2F179 T238 V239 V264 R268 Q365 V442 Y443 L503F179-F266 HydrophobicContact CB-CD1 3.8Å; F179-F266 HydrophobicContact CB-CD2 3.95Å; F179-F266 HydrophobicContact CB-CE1 3.77Å; F179-F266 HydrophobicContact CB-CE2 3.93Å; F179-F266 HydrophobicContact CB-CG 3.89Å; F179-F266 HydrophobicContact CB-CZ 3.83Å; F179-F266 HydrophobicContact CD1-CB 3.85Å; F179-F266 HydrophobicContact CD1-CD1 4.46Å; F179-F266 HydrophobicContact CD1-CD2 4.07Å; F179-F266 AromaticContact CD1-CG 3.88Å; F179-F266 HydrophobicContact CD1-CG 3.88Å; F179-F266 HydrophobicContact CG-CD2 4.25Å; F179-F266 HydrophobicContact CG-CG 4.29Å; T238-F266 CarbonylContact O-C 3.46Å; T238-F266 VanDerWaalsContact O-CA 3.24Å; T238-F266 WeakPolarHBondContact O-CA 3.47Å; T238-F266 WeakPolarHBondContact O-CB 3.24Å; V239-F266 HydrophobicContact CG2-CB 4.33Å; V264-F266 HydrophobicContact CG1-CD1 4.29Å; F266-R268 HydrophobicContact CD2-CG 3.72Å; F266-R268 HydrophobicContact CE2-CG 3.84Å; F266-Q365 PolarHBondContact O-NE2 3.42Å; F266-Q365 PolarHBondContact O-OE1 2.86Å; F266-V442 HydrophobicContact CE1-CG1 4.12Å; F266-Y443 WeakPolarHBondContact CZ-OH 3.25Å; F266-L503 HydrophobicContact CE2-CD2 4.35Å; F266-L503 HydrophobicContact CZ-CD2 3.76Å
267D97.9Very high97.9Very high27 Ų2714.3 Ų14.314%0.1447%0.067CC..EExtended strand (participates in β ladder)trans-132.2119.5162.8-178.8-38.8000107.7S237 T238 T269 L270 R358 P362S237-D267 WeakPolarHBondContact CA-O 3.42Å; S237-D267 WeakPolarHBondContact CB-O 3.43Å; T238-D267 PolarHBondContact N-O 2.89Å; T238-D267 PolarHBondContact O-N 2.99Å; D267-T269 PolarHBondContact O-N 2.92Å; D267-T269 PolarHBondContact OD1-N 2.92Å; D267-T269 PolarHBondContact OD1-OG1 3.36Å; D267-T269 VanDerWaalsContact OD1-OG1 3.1Å; D267-L270 HydrophobicContact CB-CB 3.77Å; D267-L270 HydrophobicContact CB-CD2 4.39Å; D267-L270 PolarHBondContact OD1-N 3.16Å; D267-L270 WeakPolarHBondContact OD2-CB 3.41Å; D267-R358 IonicContact OD1-NH2 3.84Å; D267-R358 PolarHBondContact OD1-NH2 2.65Å; D267-R358 IonicContact OD2-CZ 2.64Å; D267-R358 VanDerWaalsContact OD2-CZ 3.26Å; D267-R358 IonicContact OD2-NE 2.82Å; D267-R358 PolarHBondContact OD2-NE 2.89Å; D267-R358 IonicContact OD2-NH2 3.31Å; D267-R358 PolarHBondContact OD2-NH2 2.73Å; D267-P362 HydrophobicContact CB-CG 4.25Å
268R96.3Very high97.9Very high14 Ų1416.4 Ų16.45%0.0537%0.074CC..SBendtrans-76.81.5-173-63.4-17155.5136.92.4114.1F179 E184 F266F179-R268 HydrophobicContact CB-CG 4.5Å; F179-R268 HydrophobicContact CD1-CG 4.15Å; F179-R268 HydrophobicContact CD2-CG 3.86Å; F179-R268 VanDerWaalsContact CD2-CZ 3.43Å; F179-R268 HydrophobicContact CE1-CG 4.31Å; F179-R268 HydrophobicContact CE2-CG 4.03Å; F179-R268 HydrophobicContact CG-CG 3.92Å; F179-R268 HydrophobicContact CZ-CG 4.25Å; F179-R268 PolarHBondContact O-NH1 2.95Å; E184-R268 IonicContact OE1-CZ 2.75Å; E184-R268 IonicContact OE1-NH1 3.71Å; E184-R268 PolarHBondContact OE1-NH1 3.29Å; E184-R268 IonicContact OE1-NH2 2.66Å; E184-R268 PolarHBondContact OE1-NH2 3.08Å; E184-R268 IonicContact OE2-CZ 3.22Å; E184-R268 IonicContact OE2-NH1 3.73Å; E184-R268 PolarHBondContact OE2-NH1 2.93Å; E184-R268 IonicContact OE2-NH2 3.26Å; F266-R268 HydrophobicContact CD2-CG 3.72Å; F266-R268 HydrophobicContact CE2-CG 3.84Å
269T96.1Very high98Very high31 Ų3115.4 Ų15.419%0.197%0.069CC..SBendtrans-139.2-15.8-175.661.90000115.2L115 G236 D267 G271 R358L115-T269 HydrophobicContact CD2-CG2 3.71Å; G236-T269 CarbonylContact O-C 3.58Å; D267-T269 PolarHBondContact O-N 2.92Å; D267-T269 PolarHBondContact OD1-N 2.92Å; D267-T269 PolarHBondContact OD1-OG1 3.36Å; D267-T269 VanDerWaalsContact OD1-OG1 3.1Å; T269-G271 PolarHBondContact O-N 2.86Å; T269-R358 PolarHBondContact OG1-NH2 3.39Å
270L97.8Very high98Very high0 Ų016.6 Ų16.60%07%0.074CC..  trans-74.2111.7173177.863.6000110.3M233 S237 T238 D267 L355 R358 V359M233-L270 HydrophobicContact CE-CD1 3.78Å; M233-L270 HydrophobicContact CE-CG 3.82Å; S237-L270 CarbonylContact C-O 3.43Å; S237-L270 WeakPolarHBondContact CA-O 3.44Å; T238-L270 PolarHBondContact N-O 2.65Å; T238-L270 WeakPolarHBondContact OG1-CG 3.49Å; T238-L270 PolarHBondContact OG1-O 2.86Å; D267-L270 HydrophobicContact CB-CB 3.77Å; D267-L270 HydrophobicContact CB-CD2 4.39Å; D267-L270 PolarHBondContact OD1-N 3.16Å; D267-L270 WeakPolarHBondContact OD2-CB 3.41Å; L270-L355 HydrophobicContact CD1-CB 3.72Å; L270-L355 HydrophobicContact CD1-CD2 4.19Å; L270-L355 HydrophobicContact CD1-CG 4.47Å; L270-L355 VanDerWaalsContact CD1-O 3.28Å; L270-L355 WeakPolarHBondContact CD1-O 3.37Å; L270-R358 HydrophobicContact CD1-CB 4.42Å; L270-R358 HydrophobicContact CD2-CB 3.86Å; L270-V359 HydrophobicContact CD2-CG2 4.48Å
271G97Very high98.1Very high0 Ų019 Ų190%09%0.085CC..SBendtrans-175.9174.4-179.900000113G234 S235 T269 L273 E274G234-G271 WeakPolarHBondContact O-CA 3.45Å; S235-G271 CarbonylContact O-C 3.22Å; S235-G271 VanDerWaalsContact O-C 3.25Å; S235-G271 WeakPolarHBondContact O-CA 3.4Å; T269-G271 PolarHBondContact O-N 2.86Å; G271-L273 VanDerWaalsContact C-N 3.26Å; G271-L273 PolarHBondContact O-N 3.48Å; G271-E274 WeakPolarHBondContact O-CB 3.38Å; G271-E274 PolarHBondContact O-N 3.04Å
272G98Very high98Very high0 Ų022.7 Ų22.70%010%0.099CC..Hα-helixtrans-56.6-28.6-176.300000116.1G234 S235 E274 M275 E276G234-G272 PolarHBondContact O-N 3.01Å; S235-G272 PolarHBondContact O-N 3.45Å; S235-G272 VanDerWaalsContact O-N 3.13Å; G272-E274 VanDerWaalsContact C-N 3.3Å; G272-E274 PolarHBondContact O-N 3.03Å; G272-M275 WeakPolarHBondContact O-CB 3.43Å; G272-M275 PolarHBondContact O-N 3.17Å; G272-E276 WeakPolarHBondContact O-CG 3.37Å; G272-E276 PolarHBondContact O-N 2.82Å
273L98.1Very high98Very high2 Ų218.3 Ų18.31%0.018%0.082CC..Hα-helixtrans-61.4-40174.817461.6000111.5Y99 F120 S235 G271 M275 E276 L277Y99-L273 HydrophobicContact CD1-CD2 3.81Å; Y99-L273 HydrophobicContact CD2-CD1 4.34Å; Y99-L273 HydrophobicContact CD2-CD2 3.99Å; Y99-L273 HydrophobicContact CE1-CB 4.03Å; Y99-L273 HydrophobicContact CE1-CD2 3.83Å; Y99-L273 HydrophobicContact CE1-CG 4.37Å; Y99-L273 HydrophobicContact CE2-CD1 3.78Å; Y99-L273 HydrophobicContact CE2-CD2 4.03Å; Y99-L273 HydrophobicContact CE2-CG 4.34Å; Y99-L273 HydrophobicContact CG-CD2 3.89Å; F120-L273 HydrophobicContact CE2-CD2 4.45Å; F120-L273 HydrophobicContact CZ-CD1 4.16Å; F120-L273 HydrophobicContact CZ-CD2 4.11Å; S235-L273 VanDerWaalsContact O-CB 3.26Å; S235-L273 WeakPolarHBondContact O-CB 3.5Å; S235-L273 PolarHBondContact O-N 2.95Å; G271-L273 VanDerWaalsContact C-N 3.26Å; G271-L273 PolarHBondContact O-N 3.48Å; L273-M275 PolarHBondContact O-N 3.02Å; L273-E276 WeakPolarHBondContact O-CB 3.49Å; L273-E276 PolarHBondContact O-N 3.2Å; L273-E276 VanDerWaalsContact O-N 3.14Å; L273-L277 HydrophobicContact CD1-CD1 4.01Å; L273-L277 HydrophobicContact CD1-CD2 4.42Å; L273-L277 HydrophobicContact CD1-CG 3.97Å; L273-L277 HydrophobicContact CD2-CD1 4.46Å; L273-L277 HydrophobicContact CG-CD1 3.84Å; L273-L277 HydrophobicContact CG-CG 4.27Å; L273-L277 VanDerWaalsContact O-CG 3.25Å; L273-L277 WeakPolarHBondContact O-CG 3.46Å; L273-L277 PolarHBondContact O-N 2.83Å
274E97.9Very high98Very high37 Ų3718.3 Ų18.317%0.1738%0.082CC..Hα-helixtrans-73.1-24.3-174.1-160.947.6-13600111.4R119 G271 G272 R278 L355R119-E274 IonicContact CZ-OE2 3.78Å; R119-E274 VanDerWaalsContact CZ-OE2 3.29Å; R119-E274 IonicContact NE-OE2 3.12Å; R119-E274 PolarHBondContact NE-OE2 3.06Å; R119-E274 VanDerWaalsContact NE-OE2 3.08Å; R119-E274 IonicContact NH2-OE2 3.51Å; R119-E274 PolarHBondContact NH2-OE2 3.28Å; G271-E274 WeakPolarHBondContact O-CB 3.38Å; G271-E274 PolarHBondContact O-N 3.04Å; G272-E274 VanDerWaalsContact C-N 3.3Å; G272-E274 PolarHBondContact O-N 3.03Å; E274-R278 WeakPolarHBondContact O-CD 3.47Å; E274-R278 PolarHBondContact O-NH1 3.09Å; E274-R278 IonicContact OE1-CZ 2.68Å; E274-R278 IonicContact OE1-NH1 2.7Å; E274-R278 PolarHBondContact OE1-NH1 3.28Å; E274-L355 HydrophobicContact CB-CD1 4.02Å; E274-L355 HydrophobicContact CG-CD1 4.02Å; E274-L355 HydrophobicContact CG-CD2 3.84Å
275M98.6Very high98Very high0 Ų018.8 Ų18.80%09%0.089CC..Hα-helixtrans-74.3-42.8166.3-63.5171.2178.100112.3M233 G272 L273 L277 R278 L279 F348 L355 F356 V389 V392M233-M275 HydrophobicContact CE-CE 3.45Å; M233-M275 VanDerWaalsContact CE-CE 3.45Å; G272-M275 WeakPolarHBondContact O-CB 3.43Å; G272-M275 PolarHBondContact O-N 3.17Å; L273-M275 PolarHBondContact O-N 3.02Å; M275-L277 VanDerWaalsContact C-N 3.33Å; M275-L277 PolarHBondContact O-N 3.22Å; M275-R278 PolarHBondContact O-N 3.1Å; M275-L279 PolarHBondContact O-N 2.8Å; M275-L279 VanDerWaalsContact O-N 3.09Å; M275-F348 HydrophobicContact CB-CE2 3.91Å; M275-F348 HydrophobicContact CB-CZ 4.07Å; M275-F348 HydrophobicContact CG-CE2 4.47Å; M275-F348 HydrophobicContact CG-CZ 4.35Å; M275-F348 HydrophobicContact SD-CZ 4.21Å; M275-L355 HydrophobicContact CG-CD1 3.78Å; M275-F356 HydrophobicContact CE-CD1 4.35Å; M275-F356 HydrophobicContact CE-CE1 3.65Å; M275-F356 HydrophobicContact CE-CZ 4.4Å; M275-V389 HydrophobicContact SD-CG2 4.13Å; M275-V392 HydrophobicContact CE-CG2 3.95Å
276E98.4Very high98Very high7 Ų719.9 Ų19.93%0.0339%0.094CC..Hα-helixtrans-63.8-36.2176.8-74.3164.4-129.300112.9G272 L273 L279 R280 L310 A313 N314 K317G272-E276 WeakPolarHBondContact O-CG 3.37Å; G272-E276 PolarHBondContact O-N 2.82Å; L273-E276 WeakPolarHBondContact O-CB 3.49Å; L273-E276 PolarHBondContact O-N 3.2Å; L273-E276 VanDerWaalsContact O-N 3.14Å; E276-L279 PolarHBondContact O-N 3.12Å; E276-R280 VanDerWaalsContact O-CB 3.31Å; E276-R280 WeakPolarHBondContact O-CB 3.27Å; E276-R280 PolarHBondContact O-N 3.15Å; E276-L310 HydrophobicContact CB-CD1 4.16Å; E276-A313 WeakPolarHBondContact O-CB 3.28Å; E276-N314 HydrophobicContact CG-CB 4.22Å; E276-N314 PolarHBondContact OE1-ND2 3.16Å; E276-N314 VanDerWaalsContact OE1-ND2 3.12Å; E276-N314 WeakPolarHBondContact OE2-CB 3.49Å; E276-N314 PolarHBondContact OE2-ND2 2.75Å; E276-K317 HydrophobicContact CG-CD 4.11Å; E276-K317 IonicContact OE1-NZ 2.69Å; E276-K317 PolarHBondContact OE1-NZ 3.38Å
277L98.5Very high98Very high17 Ų1719.5 Ų19.59%0.0899%0.093CC..Hα-helixtrans-69-38.7178.3-69.4167.6000111.9R119 L273 M275 R280 E281R119-L277 HydrophobicContact CB-CD1 4.14Å; R119-L277 HydrophobicContact CG-CD1 3.62Å; L273-L277 HydrophobicContact CD1-CD1 4.01Å; L273-L277 HydrophobicContact CD1-CD2 4.42Å; L273-L277 HydrophobicContact CD1-CG 3.97Å; L273-L277 HydrophobicContact CD2-CD1 4.46Å; L273-L277 HydrophobicContact CG-CD1 3.84Å; L273-L277 HydrophobicContact CG-CG 4.27Å; L273-L277 VanDerWaalsContact O-CG 3.25Å; L273-L277 WeakPolarHBondContact O-CG 3.46Å; L273-L277 PolarHBondContact O-N 2.83Å; M275-L277 VanDerWaalsContact C-N 3.33Å; M275-L277 PolarHBondContact O-N 3.22Å; L277-R280 VanDerWaalsContact CD2-CZ 3.45Å; L277-R280 PolarHBondContact O-N 3.4Å; L277-E281 VanDerWaalsContact O-CB 3.32Å; L277-E281 WeakPolarHBondContact O-CB 3.42Å; L277-E281 PolarHBondContact O-N 3.11Å
278R98.5Very high97.9Very high47 Ų4719.8 Ų19.818%0.1779%0.094CC..Hα-helixtrans-60-48.4170.2-76.5159173.4632.1111.7E274 M275 E281 R282 L351 C352 D354E274-R278 WeakPolarHBondContact O-CD 3.47Å; E274-R278 PolarHBondContact O-NH1 3.09Å; E274-R278 IonicContact OE1-CZ 2.68Å; E274-R278 IonicContact OE1-NH1 2.7Å; E274-R278 PolarHBondContact OE1-NH1 3.28Å; M275-R278 PolarHBondContact O-N 3.1Å; R278-E281 PolarHBondContact O-N 2.94Å; R278-R282 WeakPolarHBondContact O-CB 3.49Å; R278-R282 PolarHBondContact O-N 3.3Å; R278-L351 HydrophobicContact CB-CB 4.41Å; R278-L351 WeakPolarHBondContact CD-O 3.47Å; R278-L351 PolarHBondContact NE-O 3.28Å; R278-L351 VanDerWaalsContact NE-O 3.13Å; R278-C352 VanDerWaalsContact CD-SG 3.54Å; R278-D354 IonicContact CZ-OD1 3.84Å; R278-D354 IonicContact CZ-OD2 3.23Å; R278-D354 IonicContact NE-OD1 3.35Å; R278-D354 PolarHBondContact NE-OD1 3.38Å; R278-D354 IonicContact NH2-OD1 2.7Å; R278-D354 PolarHBondContact NH2-OD1 3.1Å; R278-D354 IonicContact NH2-OD2 2.67Å; R278-D354 PolarHBondContact NH2-OD2 3.35Å
279L98.6Very high97.8Very high1 Ų124.5 Ų24.51%0.00512%0.117CC..Hα-helixtrans-61.4-46.7176-78.7172.7000111.7M275 E276 E281 R282 L283 A313 L316 K317 V343 F348M275-L279 PolarHBondContact O-N 2.8Å; M275-L279 VanDerWaalsContact O-N 3.09Å; E276-L279 PolarHBondContact O-N 3.12Å; L279-E281 VanDerWaalsContact C-N 3.29Å; L279-E281 PolarHBondContact O-N 3.18Å; L279-R282 PolarHBondContact O-N 3.2Å; L279-L283 WeakPolarHBondContact O-CG 3.42Å; L279-L283 PolarHBondContact O-N 2.66Å; L279-A313 HydrophobicContact CB-CB 3.68Å; L279-A313 WeakPolarHBondContact CD1-O 3.39Å; L279-L316 HydrophobicContact CD1-CB 4.2Å; L279-K317 HydrophobicContact CD1-CB 4.05Å; L279-V343 HydrophobicContact CD2-CG1 4.19Å; L279-F348 HydrophobicContact CD1-CD2 3.6Å; L279-F348 HydrophobicContact CD1-CE2 3.64Å; L279-F348 HydrophobicContact CD1-CG 4.45Å; L279-F348 HydrophobicContact CD2-CB 4.27Å; L279-F348 HydrophobicContact CD2-CD2 3.72Å; L279-F348 HydrophobicContact CD2-CG 4.33Å; L279-F348 HydrophobicContact CG-CD2 3.62Å; L279-F348 HydrophobicContact CG-CE2 3.96Å
280R98.5Very high97.7Very high24 Ų2427.4 Ų27.49%0.09113%0.128CC..Hα-helixtrans-54-46.6175.8-179-174.677.4175.10.2111.2R119 E276 L277 L283 A284 M306 L309 L310 A313R119-R280 PolarHBondContact O-NH1 3.04Å; R119-R280 PolarHBondContact O-NH2 3.3Å; E276-R280 VanDerWaalsContact O-CB 3.31Å; E276-R280 WeakPolarHBondContact O-CB 3.27Å; E276-R280 PolarHBondContact O-N 3.15Å; L277-R280 VanDerWaalsContact CD2-CZ 3.45Å; L277-R280 PolarHBondContact O-N 3.4Å; R280-L283 PolarHBondContact O-N 3.18Å; R280-A284 WeakPolarHBondContact O-CB 3.28Å; R280-A284 PolarHBondContact O-N 2.86Å; R280-M306 HydrophobicContact CG-CE 4.03Å; R280-L309 HydrophobicContact CG-CB 3.99Å; R280-L310 HydrophobicContact CG-CB 4.41Å; R280-A313 HydrophobicContact CB-CB 4.2Å
281E98.4Very high97.3Very high85 Ų8528.7 Ų28.740%0.39713%0.133SC..Hα-helixtrans-68.4-39.7-179.2-175.854.2-149.900112.2L277 R278 L279 A284 G285 R300L277-E281 VanDerWaalsContact O-CB 3.32Å; L277-E281 WeakPolarHBondContact O-CB 3.42Å; L277-E281 PolarHBondContact O-N 3.11Å; R278-E281 PolarHBondContact O-N 2.94Å; L279-E281 VanDerWaalsContact C-N 3.29Å; L279-E281 PolarHBondContact O-N 3.18Å; E281-A284 PolarHBondContact O-N 3.13Å; E281-G285 PolarHBondContact O-N 2.95Å; E281-R300 PolarHBondContact O-NH2 3.12Å; E281-R300 IonicContact OE1-CZ 3.91Å; E281-R300 IonicContact OE1-NE 2.73Å; E281-R300 PolarHBondContact OE1-NE 3.12Å; E281-R300 IonicContact OE1-NH2 3.15Å; E281-R300 PolarHBondContact OE1-NH2 2.62Å; E281-R300 IonicContact OE2-CZ 3.93Å; E281-R300 IonicContact OE2-NE 3.15Å; E281-R300 PolarHBondContact OE2-NE 3.12Å; E281-R300 IonicContact OE2-NH2 2.76Å
282R98.4Very high96.9Very high77 Ų7737.4 Ų37.429%0.29117%0.171SC..Hα-helixtrans-62.3-45.9172.8177.558.1175.1144.3-0.3112.2R278 L279 A284 G285 L286 E289 E347 L351R278-R282 WeakPolarHBondContact O-CB 3.49Å; R278-R282 PolarHBondContact O-N 3.3Å; L279-R282 PolarHBondContact O-N 3.2Å; R282-A284 VanDerWaalsContact C-N 3.32Å; R282-A284 PolarHBondContact O-N 2.85Å; R282-G285 PolarHBondContact O-N 3.47Å; R282-L286 HydrophobicContact CG-CD1 4.13Å; R282-L286 WeakPolarHBondContact O-CG 3.46Å; R282-L286 PolarHBondContact O-N 3.06Å; R282-E289 IonicContact NH1-OE2 2.75Å; R282-E347 IonicContact CZ-OE1 3.2Å; R282-E347 IonicContact NE-OE1 2.87Å; R282-E347 PolarHBondContact NE-OE1 2.73Å; R282-E347 IonicContact NH2-OE1 3.2Å; R282-E347 PolarHBondContact NH2-OE1 2.75Å; R282-L351 HydrophobicContact CB-CD1 3.84Å; R282-L351 HydrophobicContact CG-CD1 3.94Å
283L98.6Very high96.2Very high1 Ų141.3 Ų41.31%0.00521%0.211CC..Hα-helixtrans-62.7-38.7175.9-63.2-175.3000111.7L279 R280 L286 F287 L309 E312 L316 A328 F339 V343L279-L283 WeakPolarHBondContact O-CG 3.42Å; L279-L283 PolarHBondContact O-N 2.66Å; R280-L283 PolarHBondContact O-N 3.18Å; L283-L286 HydrophobicContact CD2-CD1 4.47Å; L283-L286 PolarHBondContact O-N 2.86Å; L283-F287 PolarHBondContact O-N 3.47Å; L283-L309 HydrophobicContact CB-CD2 3.51Å; L283-L309 HydrophobicContact CD1-CD2 4.14Å; L283-E312 HydrophobicContact CD1-CB 4.3Å; L283-E312 HydrophobicContact CD1-CG 4.29Å; L283-L316 HydrophobicContact CD1-CD1 3.82Å; L283-L316 HydrophobicContact CD2-CD1 3.9Å; L283-L316 HydrophobicContact CG-CD1 4.24Å; L283-A328 HydrophobicContact CD2-CB 3.98Å; L283-F339 HydrophobicContact CB-CE1 4.01Å; L283-F339 HydrophobicContact CB-CZ 4.07Å; L283-F339 HydrophobicContact CD1-CE1 4.31Å; L283-F339 HydrophobicContact CD2-CE1 3.88Å; L283-F339 HydrophobicContact CD2-CZ 3.88Å; L283-F339 HydrophobicContact CG-CE1 4.27Å; L283-F339 HydrophobicContact CG-CZ 4.49Å; L283-V343 HydrophobicContact CD2-CG2 3.8Å
284A98.3Very high95.4Very high0 Ų046.8 Ų46.80%024%0.237CC..Hα-helixtrans-63.9-38.1174.900000112.5R280 E281 R282 N288 V299 R300 M306 L309R280-A284 WeakPolarHBondContact O-CB 3.28Å; R280-A284 PolarHBondContact O-N 2.86Å; E281-A284 PolarHBondContact O-N 3.13Å; R282-A284 VanDerWaalsContact C-N 3.32Å; R282-A284 PolarHBondContact O-N 2.85Å; A284-N288 VanDerWaalsContact O-CG 3.3Å; A284-N288 PolarHBondContact O-N 2.63Å; A284-V299 HydrophobicContact CB-CG1 3.63Å; A284-R300 HydrophobicContact CB-CG 4.42Å; A284-M306 HydrophobicContact CB-CE 4.43Å; A284-M306 HydrophobicContact CB-SD 4.17Å; A284-L309 HydrophobicContact CB-CD1 4.14Å
285G98.1Very high94.6Very high16 Ų1657 Ų5717%0.16527%0.274CS..Hα-helixtrans-59.8-53.6169.800000112.2E281 R282 F287 N288 E289E281-G285 PolarHBondContact O-N 2.95Å; R282-G285 PolarHBondContact O-N 3.47Å; G285-F287 PolarHBondContact O-N 3.41Å; G285-N288 PolarHBondContact O-N 3.35Å; G285-N288 VanDerWaalsContact O-N 3.16Å; G285-E289 WeakPolarHBondContact O-CG 3.49Å; G285-E289 PolarHBondContact O-N 3.35Å
286L97.8Very high94Very high23 Ų2358.8 Ų58.812%0.1229%0.289CS..Hα-helixtrans-57.7-41.9-178.6-75.4164.3000113.2R282 L283 E289 Q290 F339 A341R282-L286 HydrophobicContact CG-CD1 4.13Å; R282-L286 WeakPolarHBondContact O-CG 3.46Å; R282-L286 PolarHBondContact O-N 3.06Å; L283-L286 HydrophobicContact CD2-CD1 4.47Å; L283-L286 PolarHBondContact O-N 2.86Å; L286-E289 PolarHBondContact O-N 3.5Å; L286-Q290 VanDerWaalsContact O-CG 3.29Å; L286-Q290 WeakPolarHBondContact O-CG 3.26Å; L286-Q290 PolarHBondContact O-N 3.17Å; L286-F339 HydrophobicContact CB-CE2 3.98Å; L286-F339 HydrophobicContact CB-CZ 4.16Å; L286-A341 HydrophobicContact CD1-CB 4.05Å
287F97.4Very high93.7Very high0 Ų064.7 Ų64.70%031%0.314CS..Hα-helixtrans-67.8-39.2177.2179.1-108.7000112.7L283 G285 E289 Q290 R291 V299 L333 M334 V337 F339L283-F287 PolarHBondContact O-N 3.47Å; G285-F287 PolarHBondContact O-N 3.41Å; F287-E289 VanDerWaalsContact C-N 3.34Å; F287-Q290 PolarHBondContact O-N 2.89Å; F287-R291 VanDerWaalsContact CZ-CD 3.46Å; F287-R291 PolarHBondContact O-N 3.39Å; F287-V299 HydrophobicContact CD1-CB 3.78Å; F287-V299 HydrophobicContact CD1-CG1 4.22Å; F287-V299 HydrophobicContact CD1-CG2 3.9Å; F287-V299 HydrophobicContact CE1-CB 4.11Å; F287-V299 HydrophobicContact CE1-CG2 4.01Å; F287-L333 HydrophobicContact CB-CD2 4.07Å; F287-L333 HydrophobicContact CD1-CD2 3.9Å; F287-L333 HydrophobicContact CD2-CD2 3.74Å; F287-L333 HydrophobicContact CE1-CD2 4.16Å; F287-L333 HydrophobicContact CE1-CG 4.35Å; F287-L333 HydrophobicContact CE2-CB 4.18Å; F287-L333 HydrophobicContact CE2-CD2 4Å; F287-L333 HydrophobicContact CE2-CG 4.37Å; F287-L333 HydrophobicContact CG-CD2 3.64Å; F287-L333 HydrophobicContact CZ-CB 4.24Å; F287-L333 HydrophobicContact CZ-CD2 4.18Å; F287-L333 HydrophobicContact CZ-CG 4.23Å; F287-M334 HydrophobicContact CE1-CB 3.94Å; F287-M334 HydrophobicContact CE1-CE 4.4Å; F287-M334 HydrophobicContact CZ-CB 4.03Å; F287-V337 HydrophobicContact CE2-CB 4.14Å; F287-V337 HydrophobicContact CE2-CG1 3.96Å; F287-V337 HydrophobicContact CZ-CB 4.2Å; F287-V337 HydrophobicContact CZ-CG1 4.45Å; F287-F339 HydrophobicContact CB-CD2 3.7Å; F287-F339 HydrophobicContact CB-CE2 3.94Å; F287-F339 HydrophobicContact CB-CG 4.36Å; F287-F339 HydrophobicContact CD2-CB 3.79Å; F287-F339 AromaticContact CD2-CD2 3.8Å; F287-F339 HydrophobicContact CD2-CD2 3.8Å; F287-F339 HydrophobicContact CD2-CG 4.11Å; F287-F339 HydrophobicContact CE2-CB 4.22Å; F287-F339 HydrophobicContact CG-CD2 4.21Å
288N96.6Very high93.6Very high34 Ų3466.6 Ų66.618%0.18233%0.325CS..Hα-helixtrans-68.4-34.4175.3-68.9-2.2000111.9A284 G285 R291 K292 D298 V299 R300A284-N288 VanDerWaalsContact O-CG 3.3Å; A284-N288 PolarHBondContact O-N 2.63Å; G285-N288 PolarHBondContact O-N 3.35Å; G285-N288 VanDerWaalsContact O-N 3.16Å; N288-R291 CarbonylContact O-C 3.39Å; N288-R291 PolarHBondContact O-N 2.82Å; N288-K292 PolarHBondContact O-N 2.95Å; N288-D298 PolarHBondContact ND2-OD1 3.17Å; N288-D298 PolarHBondContact ND2-OD2 3.39Å; N288-V299 WeakPolarHBondContact OD1-CG1 3.35Å; N288-V299 PolarHBondContact OD1-N 2.64Å; N288-R300 PolarHBondContact ND2-NH1 3.2Å
289E94.9Very high93.5Very high113 Ų11364.4 Ų64.453%0.52832%0.316SS..Hα-helixtrans-62.7-44.2172-74.2169179.400111.4R282 G285 L286 F287 R291 K292R282-E289 IonicContact NH1-OE2 2.75Å; G285-E289 WeakPolarHBondContact O-CG 3.49Å; G285-E289 PolarHBondContact O-N 3.35Å; L286-E289 PolarHBondContact O-N 3.5Å; F287-E289 VanDerWaalsContact C-N 3.34Å; E289-R291 PolarHBondContact O-N 2.85Å; E289-K292 WeakPolarHBondContact O-CB 3.34Å; E289-K292 PolarHBondContact O-N 3.28Å
290Q92.5Very high93.4Very high92 Ų9268.3 Ų68.343%0.4333%0.331SS..Hα-helixtrans-61-27.3174.7-73.1172.91.900113.4L286 F287 K340L286-Q290 VanDerWaalsContact O-CG 3.29Å; L286-Q290 WeakPolarHBondContact O-CG 3.26Å; L286-Q290 PolarHBondContact O-N 3.17Å; F287-Q290 PolarHBondContact O-N 2.89Å; Q290-K340 PolarHBondContact NE2-O 2.75Å
291R90.8Very high93.2Very high26 Ų2672.6 Ų72.610%0.09835%0.352CS..THydrogen-bonded Turntrans-102.59.2179.1-60.4-175.369.7-162.50.9113.9F287 N288 E289 G293 Q294 A296 D335F287-R291 VanDerWaalsContact CZ-CD 3.46Å; F287-R291 PolarHBondContact O-N 3.39Å; N288-R291 CarbonylContact O-C 3.39Å; N288-R291 PolarHBondContact O-N 2.82Å; E289-R291 PolarHBondContact O-N 2.85Å; R291-G293 PolarHBondContact O-N 2.84Å; R291-Q294 VanDerWaalsContact O-CB 3.31Å; R291-Q294 WeakPolarHBondContact O-CB 3.14Å; R291-Q294 WeakPolarHBondContact O-CG 3.46Å; R291-Q294 PolarHBondContact O-N 3.41Å; R291-A296 HydrophobicContact CB-CB 4.08Å; R291-D335 IonicContact CZ-OD2 3.23Å; R291-D335 VanDerWaalsContact CZ-OD2 3.23Å; R291-D335 IonicContact NH1-OD2 3.84Å; R291-D335 PolarHBondContact NH1-OD2 2.94Å; R291-D335 IonicContact NH2-OD2 2.78Å; R291-D335 PolarHBondContact NH2-OD2 2.87Å
292K87.8Confident93.1Very high183 Ų18371 Ų7180%0.79635%0.346SS*.THydrogen-bonded Turntrans-59.3126.9-179.1-169.8171.5-176.4173.40111N288 E289N288-K292 PolarHBondContact O-N 2.95Å; E289-K292 WeakPolarHBondContact O-CB 3.34Å; E289-K292 PolarHBondContact O-N 3.28Å
293G82.6Confident93Very high82 Ų8269.4 Ų69.485%0.84535%0.346SS*.THydrogen-bonded Turntrans91.8-13.9-176.200000115.3R291 R295R291-G293 PolarHBondContact O-N 2.84Å; G293-R295 PolarHBondContact O-N 3.25Å
294Q82.9Confident92.8Very high117 Ų11776 Ų7655%0.54737%0.371SS..THydrogen-bonded Turntrans-80.24.5-177.6-58.5176.22.800114.4R291 A296R291-Q294 VanDerWaalsContact O-CB 3.31Å; R291-Q294 WeakPolarHBondContact O-CB 3.14Å; R291-Q294 WeakPolarHBondContact O-CG 3.46Å; R291-Q294 PolarHBondContact O-N 3.41Å; Q294-A296 PolarHBondContact O-N 3.41Å; Q294-A296 VanDerWaalsContact O-N 3.17Å
295R81.1Confident92.8Very high251 Ų25176 Ų7695%0.94737%0.371SS*.THydrogen-bonded Turntrans52.128.8-168.3-156-174.9177172.2-0.2113.5G293G293-R295 PolarHBondContact O-N 3.25Å
296A85.3Confident92.8Very high39 Ų3976 Ų7632%0.32237%0.367SS..PPolyproline II helixtrans-67157.4172.300000111.5R291 Q294R291-A296 HydrophobicContact CB-CB 4.08Å; Q294-A296 PolarHBondContact O-N 3.41Å; Q294-A296 VanDerWaalsContact O-N 3.17Å
297K92.7Very high92.7Very high130 Ų13075.2 Ų75.257%0.56536%0.363SS*.PPolyproline II helixtrans-75.1161.3168.1-70.8-179.6155.6-123.50111.2E301 M334K297-E301 WeakPolarHBondContact CD-OE2 3.47Å; K297-E301 IonicContact NZ-OE2 3.95Å; K297-E301 PolarHBondContact NZ-OE2 2.6Å; K297-M334 HydrophobicContact CB-CE 4.14Å; K297-M334 WeakPolarHBondContact O-CE 3.23Å
298D95.3Very high92.8Very high58 Ų5876.8 Ų76.831%0.3137%0.37SS..PPolyproline II helixtrans-69.5131.1167.9-164.9-47.6000109.6N288 R300 E301N288-D298 PolarHBondContact ND2-OD1 3.17Å; N288-D298 PolarHBondContact ND2-OD2 3.39Å; D298-R300 PolarHBondContact O-N 3.5Å; D298-R300 VanDerWaalsContact O-N 3.12Å; D298-R300 VanDerWaalsContact OD1-CB 3.25Å; D298-R300 WeakPolarHBondContact OD1-CB 3.49Å; D298-R300 VanDerWaalsContact OD1-CG 3.23Å; D298-R300 WeakPolarHBondContact OD1-CG 3.42Å; D298-R300 IonicContact OD1-CZ 3.15Å; D298-R300 PolarHBondContact OD1-N 2.86Å; D298-R300 IonicContact OD1-NH1 3.18Å; D298-R300 PolarHBondContact OD1-NH1 3.25Å; D298-R300 IonicContact OD2-NH1 3.86Å; D298-R300 PolarHBondContact OD2-NH1 2.97Å; D298-E301 HydrophobicContact CB-CG 4.47Å; D298-E301 VanDerWaalsContact O-CB 3.32Å; D298-E301 WeakPolarHBondContact O-CB 3.47Å; D298-E301 PolarHBondContact O-N 2.9Å
299V96.9Very high92.8Very high0 Ų075.1 Ų75.10%036%0.361CS..G310 helixtrans-58.6-22.8176.572.60000113.7A284 F287 N288 E301 N302 A305 M306 L309 L333 M334A284-V299 HydrophobicContact CB-CG1 3.63Å; F287-V299 HydrophobicContact CD1-CB 3.78Å; F287-V299 HydrophobicContact CD1-CG1 4.22Å; F287-V299 HydrophobicContact CD1-CG2 3.9Å; F287-V299 HydrophobicContact CE1-CB 4.11Å; F287-V299 HydrophobicContact CE1-CG2 4.01Å; N288-V299 WeakPolarHBondContact OD1-CG1 3.35Å; N288-V299 PolarHBondContact OD1-N 2.64Å; V299-E301 PolarHBondContact O-N 2.98Å; V299-N302 PolarHBondContact O-N 3.35Å; V299-A305 HydrophobicContact CG2-CB 3.41Å; V299-A305 VanDerWaalsContact CG2-CB 3.41Å; V299-M306 HydrophobicContact CG1-SD 4.4Å; V299-L309 HydrophobicContact CG1-CD1 4.09Å; V299-L309 HydrophobicContact CG2-CD1 3.89Å; V299-L333 HydrophobicContact CG2-CD2 4.38Å; V299-L333 HydrophobicContact CG2-CG 4.33Å; V299-M334 HydrophobicContact CB-CE 4.3Å; V299-M334 HydrophobicContact CG2-CB 4.48Å; V299-M334 HydrophobicContact CG2-SD 4.36Å
300R96.3Very high93Very high83 Ų8370.1 Ų70.131%0.31334%0.338SS..G310 helixtrans-64.6-23.4172.8-63.2167.1-170.274-0113.2E281 A284 N288 D298 N302 M306E281-R300 PolarHBondContact O-NH2 3.12Å; E281-R300 IonicContact OE1-CZ 3.91Å; E281-R300 IonicContact OE1-NE 2.73Å; E281-R300 PolarHBondContact OE1-NE 3.12Å; E281-R300 IonicContact OE1-NH2 3.15Å; E281-R300 PolarHBondContact OE1-NH2 2.62Å; E281-R300 IonicContact OE2-CZ 3.93Å; E281-R300 IonicContact OE2-NE 3.15Å; E281-R300 PolarHBondContact OE2-NE 3.12Å; E281-R300 IonicContact OE2-NH2 2.76Å; A284-R300 HydrophobicContact CB-CG 4.42Å; N288-R300 PolarHBondContact ND2-NH1 3.2Å; D298-R300 PolarHBondContact O-N 3.5Å; D298-R300 VanDerWaalsContact O-N 3.12Å; D298-R300 VanDerWaalsContact OD1-CB 3.25Å; D298-R300 WeakPolarHBondContact OD1-CB 3.49Å; D298-R300 VanDerWaalsContact OD1-CG 3.23Å; D298-R300 WeakPolarHBondContact OD1-CG 3.42Å; D298-R300 IonicContact OD1-CZ 3.15Å; D298-R300 PolarHBondContact OD1-N 2.86Å; D298-R300 IonicContact OD1-NH1 3.18Å; D298-R300 PolarHBondContact OD1-NH1 3.25Å; D298-R300 IonicContact OD2-NH1 3.86Å; D298-R300 PolarHBondContact OD2-NH1 2.97Å; R300-N302 PolarHBondContact O-N 2.74Å; R300-M306 HydrophobicContact CB-SD 4.48Å; R300-M306 HydrophobicContact CG-CE 4.03Å; R300-M306 HydrophobicContact CG-SD 4.07Å
301E94.8Very high93.2Very high115 Ų11573.3 Ų73.354%0.53735%0.346SS..G310 helixtrans-68.4-11.7171.5-67.6177.5-134.800112.9K297 D298 V299 P303K297-E301 WeakPolarHBondContact CD-OE2 3.47Å; K297-E301 IonicContact NZ-OE2 3.95Å; K297-E301 PolarHBondContact NZ-OE2 2.6Å; D298-E301 HydrophobicContact CB-CG 4.47Å; D298-E301 VanDerWaalsContact O-CB 3.32Å; D298-E301 WeakPolarHBondContact O-CB 3.47Å; D298-E301 PolarHBondContact O-N 2.9Å; V299-E301 PolarHBondContact O-N 2.98Å; E301-P303 WeakPolarHBondContact O-CD 3.46Å
302N96.1Very high93.5Very high50 Ų5072.6 Ų72.627%0.26734%0.344SS..  trans-117.398-171.4-174.1-24.1000111.9V299 R300 R304 A305 M306 M334V299-N302 PolarHBondContact O-N 3.35Å; R300-N302 PolarHBondContact O-N 2.74Å; N302-R304 PolarHBondContact O-N 3.17Å; N302-R304 VanDerWaalsContact O-N 3.12Å; N302-R304 WeakPolarHBondContact OD1-CB 3.35Å; N302-R304 PolarHBondContact OD1-N 3.26Å; N302-R304 VanDerWaalsContact OD1-N 3.08Å; N302-A305 HydrophobicContact CB-CB 3.91Å; N302-A305 PolarHBondContact O-N 3.14Å; N302-A305 PolarHBondContact OD1-N 2.88Å; N302-A305 VanDerWaalsContact OD1-N 3.15Å; N302-M306 PolarHBondContact O-N 3.44Å; N302-M334 HydrophobicContact CB-SD 3.56Å; N302-M334 VanDerWaalsContact CB-SD 3.56Å; N302-M334 WeakPolarHBondContact ND2-CG 3.3Å; N302-M334 PolarHBondContact ND2-SD 2.84Å; N302-M334 VanDerWaalsContact ND2-SD 3.43Å
303P95.7Very high94Very high44 Ų4463.9 Ų63.929%0.28631%0.306SS..Hα-helixtrans-55.4-31178.9-30.136.9000114.7P93 E122 E301 A307P93-P303 HydrophobicContact CB-CB 4.21Å; P93-P303 HydrophobicContact CG-CB 3.7Å; E122-P303 HydrophobicContact CB-CB 4.07Å; E122-P303 HydrophobicContact CB-CG 4.33Å; E301-P303 WeakPolarHBondContact O-CD 3.46Å; P303-A307 VanDerWaalsContact O-CB 3.26Å; P303-A307 WeakPolarHBondContact O-CB 3.22Å; P303-A307 PolarHBondContact O-N 2.93Å
304R96.1Very high94.7Very high141 Ų14162 Ų6253%0.53228%0.277SS..Hα-helixtrans-72.6-36.4177.6170160.5-177.2-142-1.7111.8I90 N302 K308I90-R304 HydrophobicContact CG2-CG 4.17Å; I90-R304 WeakPolarHBondContact O-CD 3.27Å; I90-R304 WeakPolarHBondContact O-CG 3.45Å; N302-R304 PolarHBondContact O-N 3.17Å; N302-R304 VanDerWaalsContact O-N 3.12Å; N302-R304 WeakPolarHBondContact OD1-CB 3.35Å; N302-R304 PolarHBondContact OD1-N 3.26Å; N302-R304 VanDerWaalsContact OD1-N 3.08Å; R304-K308 PolarHBondContact O-N 3.24Å; R304-K308 VanDerWaalsContact O-N 3.13Å
305A97.2Very high95.4Very high0 Ų062.1 Ų62.10%027%0.272CS..Hα-helixtrans-70.5-43.5172.600000111.2V299 N302 A307 K308 L309 L333 M334V299-A305 HydrophobicContact CG2-CB 3.41Å; V299-A305 VanDerWaalsContact CG2-CB 3.41Å; N302-A305 HydrophobicContact CB-CB 3.91Å; N302-A305 PolarHBondContact O-N 3.14Å; N302-A305 PolarHBondContact OD1-N 2.88Å; N302-A305 VanDerWaalsContact OD1-N 3.15Å; A305-A307 VanDerWaalsContact C-N 3.29Å; A305-A307 PolarHBondContact O-N 2.85Å; A305-K308 WeakPolarHBondContact O-CB 3.36Å; A305-K308 PolarHBondContact O-N 3Å; A305-K308 VanDerWaalsContact O-N 3.11Å; A305-L309 WeakPolarHBondContact O-CG 3.23Å; A305-L309 PolarHBondContact O-N 3.48Å; A305-L333 HydrophobicContact CB-CD1 3.85Å; A305-L333 HydrophobicContact CB-CG 4.4Å; A305-L333 WeakPolarHBondContact CB-O 3.46Å; A305-M334 HydrophobicContact CB-CB 4.29Å
306M97.9Very high96.2Very high16 Ų1650.1 Ų50.18%0.07923%0.227CC..Hα-helixtrans-63-33174.8-66.1-59.1-76.600113R280 A284 V299 R300 N302 L309 L310R280-M306 HydrophobicContact CG-CE 4.03Å; A284-M306 HydrophobicContact CB-CE 4.43Å; A284-M306 HydrophobicContact CB-SD 4.17Å; V299-M306 HydrophobicContact CG1-SD 4.4Å; R300-M306 HydrophobicContact CB-SD 4.48Å; R300-M306 HydrophobicContact CG-CE 4.03Å; R300-M306 HydrophobicContact CG-SD 4.07Å; N302-M306 PolarHBondContact O-N 3.44Å; M306-L309 PolarHBondContact O-N 3.24Å; M306-L309 HydrophobicContact SD-CD1 3.79Å; M306-L310 WeakPolarHBondContact O-CB 3.38Å; M306-L310 PolarHBondContact O-N 2.95Å
307A96.8Very high96.8Very high5 Ų549 Ų494%0.04122%0.215CC..Hα-helixtrans-68.6-37.5171.500000113I90 P93 P303 A305 R311I90-A307 HydrophobicContact CG1-CB 4.23Å; P93-A307 HydrophobicContact CB-CB 4.33Å; P303-A307 VanDerWaalsContact O-CB 3.26Å; P303-A307 WeakPolarHBondContact O-CB 3.22Å; P303-A307 PolarHBondContact O-N 2.93Å; A305-A307 VanDerWaalsContact C-N 3.29Å; A305-A307 PolarHBondContact O-N 2.85Å; A307-R311 PolarHBondContact O-N 3.42Å
308K97.8Very high97Very high33 Ų3346.8 Ų46.814%0.14321%0.212CC..Hα-helixtrans-61.3-47.5169.9-75.1-179.7166.5-165.90110.9I90 R304 A305 R311 E312 I330 E331 G332 L333I90-K308 HydrophobicContact CD1-CG 4.26Å; I90-K308 HydrophobicContact CG2-CG 3.77Å; R304-K308 PolarHBondContact O-N 3.24Å; R304-K308 VanDerWaalsContact O-N 3.13Å; A305-K308 WeakPolarHBondContact O-CB 3.36Å; A305-K308 PolarHBondContact O-N 3Å; A305-K308 VanDerWaalsContact O-N 3.11Å; K308-R311 PolarHBondContact O-N 3.3Å; K308-E312 PolarHBondContact O-N 3.43Å; K308-E312 VanDerWaalsContact O-N 3.14Å; K308-I330 HydrophobicContact CB-CD1 4.43Å; K308-I330 HydrophobicContact CB-CG2 3.94Å; K308-I330 HydrophobicContact CD-CG2 3.73Å; K308-I330 HydrophobicContact CG-CG2 4.27Å; K308-E331 PolarHBondContact NZ-O 3.06Å; K308-G332 VanDerWaalsContact NZ-C 3.34Å; K308-G332 PolarHBondContact NZ-O 3.38Å; K308-L333 HydrophobicContact CB-CD1 3.9Å; K308-L333 HydrophobicContact CD-CD1 4.08Å
309L98.4Very high97.2Very high0 Ų045.6 Ų45.60%021%0.207CC..Hα-helixtrans-63.2-40.1-179.5-71.6160.7000112.5R280 L283 A284 V299 A305 M306 R311 E312 A313 I330 L333 F339R280-L309 HydrophobicContact CG-CB 3.99Å; L283-L309 HydrophobicContact CB-CD2 3.51Å; L283-L309 HydrophobicContact CD1-CD2 4.14Å; A284-L309 HydrophobicContact CB-CD1 4.14Å; V299-L309 HydrophobicContact CG1-CD1 4.09Å; V299-L309 HydrophobicContact CG2-CD1 3.89Å; A305-L309 WeakPolarHBondContact O-CG 3.23Å; A305-L309 PolarHBondContact O-N 3.48Å; M306-L309 PolarHBondContact O-N 3.24Å; M306-L309 HydrophobicContact SD-CD1 3.79Å; L309-R311 PolarHBondContact O-N 2.93Å; L309-E312 PolarHBondContact O-N 3.47Å; L309-A313 WeakPolarHBondContact O-CB 3.38Å; L309-A313 PolarHBondContact O-N 2.92Å; L309-I330 HydrophobicContact CD2-CD1 3.81Å; L309-I330 HydrophobicContact CG-CD1 4.23Å; L309-L333 HydrophobicContact CD1-CD1 4.19Å; L309-L333 HydrophobicContact CD1-CD2 4.27Å; L309-L333 HydrophobicContact CD2-CD1 4.32Å; L309-L333 HydrophobicContact CD2-CD2 3.87Å; L309-L333 HydrophobicContact CG-CD1 3.83Å; L309-L333 HydrophobicContact CG-CD2 4.16Å; L309-F339 HydrophobicContact CD2-CD1 4.41Å; L309-F339 HydrophobicContact CD2-CE1 4.31Å
310L97.6Very high97.2Very high8 Ų845.6 Ų45.64%0.04221%0.207CC..Hα-helixtrans-63.4-39.8175.7-177.257.4000112.2F120 E276 R280 M306 A313 N314F120-L310 HydrophobicContact CE1-CD2 4.42Å; E276-L310 HydrophobicContact CB-CD1 4.16Å; R280-L310 HydrophobicContact CG-CB 4.41Å; M306-L310 WeakPolarHBondContact O-CB 3.38Å; M306-L310 PolarHBondContact O-N 2.95Å; L310-A313 PolarHBondContact O-N 3.17Å; L310-N314 PolarHBondContact O-N 3.36Å; L310-N314 VanDerWaalsContact O-N 3.08Å
311R96.9Very high97.3Very high159 Ų15942.9 Ų42.960%0.620%0.201SC*.Hα-helixtrans-63.8-42.8176.2-171.3-17768.7170.14.8111.7A307 K308 L309 R315A307-R311 PolarHBondContact O-N 3.42Å; K308-R311 PolarHBondContact O-N 3.3Å; L309-R311 PolarHBondContact O-N 2.93Å; R311-R315 PolarHBondContact O-N 2.85Å
312E98.2Very high97.4Very high10 Ų1041.2 Ų41.25%0.04721%0.206CC..Hα-helixtrans-71.3-32.8177.3-168.569.2170.100111.8L283 K308 L309 R315 L316 A328 Q329 I330L283-E312 HydrophobicContact CD1-CB 4.3Å; L283-E312 HydrophobicContact CD1-CG 4.29Å; K308-E312 PolarHBondContact O-N 3.43Å; K308-E312 VanDerWaalsContact O-N 3.14Å; L309-E312 PolarHBondContact O-N 3.47Å; E312-R315 WeakPolarHBondContact O-CB 3.39Å; E312-R315 PolarHBondContact O-N 2.85Å; E312-R315 IonicContact OE1-NH1 2.77Å; E312-R315 PolarHBondContact OE1-NH1 2.73Å; E312-R315 WeakPolarHBondContact OE2-CD 3.46Å; E312-R315 IonicContact OE2-NH1 2.84Å; E312-R315 PolarHBondContact OE2-NH1 2.88Å; E312-R315 VanDerWaalsContact OE2-NH1 3.15Å; E312-L316 WeakPolarHBondContact O-CB 3.45Å; E312-L316 VanDerWaalsContact O-CG 3.3Å; E312-L316 WeakPolarHBondContact O-CG 3.21Å; E312-L316 PolarHBondContact O-N 2.96Å; E312-A328 HydrophobicContact CG-CB 4.24Å; E312-A328 WeakPolarHBondContact OE1-CA 3.41Å; E312-Q329 PolarHBondContact OE1-N 3.02Å; E312-I330 HydrophobicContact CB-CD1 3.76Å; E312-I330 HydrophobicContact CB-CG1 4Å; E312-I330 HydrophobicContact CG-CD1 4.19Å; E312-I330 HydrophobicContact CG-CG1 4.03Å
313A98.4Very high97.5Very high0 Ų042.7 Ų42.70%021%0.214CC..Hα-helixtrans-62.1-43.3172.800000113E276 L279 R280 L309 L310 R315 L316 K317E276-A313 WeakPolarHBondContact O-CB 3.28Å; L279-A313 HydrophobicContact CB-CB 3.68Å; L279-A313 WeakPolarHBondContact CD1-O 3.39Å; R280-A313 HydrophobicContact CB-CB 4.2Å; L309-A313 WeakPolarHBondContact O-CB 3.38Å; L309-A313 PolarHBondContact O-N 2.92Å; L310-A313 PolarHBondContact O-N 3.17Å; A313-R315 VanDerWaalsContact C-N 3.35Å; A313-L316 PolarHBondContact O-N 2.79Å; A313-K317 PolarHBondContact O-N 3Å
314N96.8Very high97.6Very high44 Ų4444.1 Ų44.124%0.23523%0.229CC..Hα-helixtrans-62-41.1173.9-176.2-83000112E43 E276 L310 T318E43-N314 PolarHBondContact OE1-ND2 2.69Å; E276-N314 HydrophobicContact CG-CB 4.22Å; E276-N314 PolarHBondContact OE1-ND2 3.16Å; E276-N314 VanDerWaalsContact OE1-ND2 3.12Å; E276-N314 WeakPolarHBondContact OE2-CB 3.49Å; E276-N314 PolarHBondContact OE2-ND2 2.75Å; L310-N314 PolarHBondContact O-N 3.36Å; L310-N314 VanDerWaalsContact O-N 3.08Å; N314-T318 PolarHBondContact O-N 3.3Å; N314-T318 PolarHBondContact O-OG1 3.47Å
315R97.3Very high97.7Very high118 Ų11840.4 Ų40.445%0.44522%0.22SC..Hα-helixtrans-61.8-48.3171.8-174.5-167-178.2-172-0.6111.7R311 E312 A313 T318 V319R311-R315 PolarHBondContact O-N 2.85Å; E312-R315 WeakPolarHBondContact O-CB 3.39Å; E312-R315 PolarHBondContact O-N 2.85Å; E312-R315 IonicContact OE1-NH1 2.77Å; E312-R315 PolarHBondContact OE1-NH1 2.73Å; E312-R315 WeakPolarHBondContact OE2-CD 3.46Å; E312-R315 IonicContact OE2-NH1 2.84Å; E312-R315 PolarHBondContact OE2-NH1 2.88Å; E312-R315 VanDerWaalsContact OE2-NH1 3.15Å; A313-R315 VanDerWaalsContact C-N 3.35Å; R315-T318 WeakPolarHBondContact O-CB 3.15Å; R315-T318 PolarHBondContact O-N 3.36Å; R315-T318 VanDerWaalsContact O-N 3.16Å; R315-V319 HydrophobicContact CG-CG2 4.2Å; R315-V319 WeakPolarHBondContact O-CG2 3.34Å; R315-V319 PolarHBondContact O-N 3.25Å
316L98Very high97.7Very high0 Ų042.9 Ų42.90%023%0.232CC..Hα-helixtrans-60.4-49179.7-75170.5000112L279 L283 E312 A313 T318 V319 L320 H326 A328 V343L279-L316 HydrophobicContact CD1-CB 4.2Å; L283-L316 HydrophobicContact CD1-CD1 3.82Å; L283-L316 HydrophobicContact CD2-CD1 3.9Å; L283-L316 HydrophobicContact CG-CD1 4.24Å; E312-L316 WeakPolarHBondContact O-CB 3.45Å; E312-L316 VanDerWaalsContact O-CG 3.3Å; E312-L316 WeakPolarHBondContact O-CG 3.21Å; E312-L316 PolarHBondContact O-N 2.96Å; A313-L316 PolarHBondContact O-N 2.79Å; L316-T318 PolarHBondContact O-N 2.78Å; L316-V319 PolarHBondContact O-N 2.96Å; L316-L320 HydrophobicContact CB-CD1 4.38Å; L316-L320 VanDerWaalsContact O-CB 3.24Å; L316-L320 WeakPolarHBondContact O-CB 3.33Å; L316-L320 VanDerWaalsContact O-CG 3.24Å; L316-L320 WeakPolarHBondContact O-CG 3.36Å; L316-L320 PolarHBondContact O-N 3.5Å; L316-H326 HydrophobicContact CD2-CB 3.93Å; L316-A328 HydrophobicContact CD1-CB 3.91Å; L316-A328 HydrophobicContact CD2-CB 4.16Å; L316-A328 HydrophobicContact CG-CB 4.45Å; L316-V343 HydrophobicContact CD1-CG2 4.17Å; L316-V343 HydrophobicContact CD2-CB 4.47Å
317K98.1Very high97.7Very high16 Ų1645.8 Ų45.87%0.0725%0.246CC..Hα-helixtrans-47.7-46.3172.9178.1-162.566.6-178.90111.1E276 L279 A313 S321 F348 V389E276-K317 HydrophobicContact CG-CD 4.11Å; E276-K317 IonicContact OE1-NZ 2.69Å; E276-K317 PolarHBondContact OE1-NZ 3.38Å; L279-K317 HydrophobicContact CD1-CB 4.05Å; A313-K317 PolarHBondContact O-N 3Å; K317-S321 PolarHBondContact O-N 3.46Å; K317-S321 PolarHBondContact O-OG 2.66Å; K317-F348 HydrophobicContact CG-CZ 4.22Å; K317-V389 HydrophobicContact CG-CG2 4.45Å
318T97.2Very high97.8Very high82 Ų8245.6 Ų45.650%0.50324%0.244SC..Hα-helixtrans-70.1-47.2-178.6-52.60000112.1N314 R315 L316 S321N314-T318 PolarHBondContact O-N 3.3Å; N314-T318 PolarHBondContact O-OG1 3.47Å; R315-T318 WeakPolarHBondContact O-CB 3.15Å; R315-T318 PolarHBondContact O-N 3.36Å; R315-T318 VanDerWaalsContact O-N 3.16Å; L316-T318 PolarHBondContact O-N 2.78Å; T318-S321 WeakPolarHBondContact O-CB 3.42Å; T318-S321 PolarHBondContact O-N 3.23Å
319V97.9Very high97.7Very high33 Ų3348.1 Ų48.120%0.226%0.257CS..Hα-helixtrans-68.6-41.4-178.9174.50000111.9R315 L316 S321 A322 N323 H326R315-V319 HydrophobicContact CG-CG2 4.2Å; R315-V319 WeakPolarHBondContact O-CG2 3.34Å; R315-V319 PolarHBondContact O-N 3.25Å; L316-V319 PolarHBondContact O-N 2.96Å; V319-S321 PolarHBondContact O-N 2.83Å; V319-A322 PolarHBondContact O-N 3.05Å; V319-A322 VanDerWaalsContact O-N 3.15Å; V319-N323 HydrophobicContact CG1-CB 4.41Å; V319-N323 WeakPolarHBondContact O-CB 3.44Å; V319-N323 PolarHBondContact O-N 2.83Å; V319-N323 PolarHBondContact O-ND2 2.77Å; V319-H326 HydrophobicContact CG1-CB 3.97Å
320L98.3Very high97.7Very high1 Ų148.6 Ų48.61%0.00526%0.259CS..Hα-helixtrans-70.5-18.8177.9-65175000112.8L316 A322 N323 H326 V343 R345 F348L316-L320 HydrophobicContact CB-CD1 4.38Å; L316-L320 VanDerWaalsContact O-CB 3.24Å; L316-L320 WeakPolarHBondContact O-CB 3.33Å; L316-L320 VanDerWaalsContact O-CG 3.24Å; L316-L320 WeakPolarHBondContact O-CG 3.36Å; L316-L320 PolarHBondContact O-N 3.5Å; L320-A322 PolarHBondContact O-N 3.5Å; L320-N323 CarbonylContact C-O 3.59Å; L320-N323 WeakPolarHBondContact CA-O 3.36Å; L320-H326 HydrophobicContact CD2-CB 4.31Å; L320-V343 HydrophobicContact CD1-CG1 4.03Å; L320-R345 VanDerWaalsContact O-CZ 3.31Å; L320-R345 PolarHBondContact O-NE 3.13Å; L320-R345 PolarHBondContact O-NH2 2.72Å; L320-F348 HydrophobicContact CD1-CB 3.93Å; L320-F348 HydrophobicContact CD1-CG 4.31Å
321S97.1Very high97.6Very high26 Ų2654.9 Ų54.918%0.18229%0.288CS..Hα-helixtrans-66-27.5170.4-62.70000112.3K317 T318 V319 R345 P390K317-S321 PolarHBondContact O-N 3.46Å; K317-S321 PolarHBondContact O-OG 2.66Å; T318-S321 WeakPolarHBondContact O-CB 3.42Å; T318-S321 PolarHBondContact O-N 3.23Å; V319-S321 PolarHBondContact O-N 2.83Å; S321-R345 PolarHBondContact O-NH2 2.97Å; S321-P390 WeakPolarHBondContact O-CG 3.43Å
322A97.3Very high97.6Very high79 Ų7948.3 Ų48.365%0.65327%0.27SS*.Hα-helixtrans-98.3-44173.600000112.7V319 L320 R345V319-A322 PolarHBondContact O-N 3.05Å; V319-A322 VanDerWaalsContact O-N 3.15Å; L320-A322 PolarHBondContact O-N 3.5Å; A322-R345 PolarHBondContact O-NH2 2.8Å
323N97.9Very high97.5Very high82 Ų8248.1 Ų48.144%0.43927%0.269SS..SBendtrans-101.5156.4-170.9-59.7-88.8000112.6V319 L320 R345V319-N323 HydrophobicContact CG1-CB 4.41Å; V319-N323 WeakPolarHBondContact O-CB 3.44Å; V319-N323 PolarHBondContact O-N 2.83Å; V319-N323 PolarHBondContact O-ND2 2.77Å; L320-N323 CarbonylContact C-O 3.59Å; L320-N323 WeakPolarHBondContact CA-O 3.36Å; N323-R345 VanDerWaalsContact C-NH2 3.31Å; N323-R345 PolarHBondContact O-NE 2.96Å; N323-R345 PolarHBondContact O-NH2 2.87Å
324A98Very high97.3Very high73 Ų7348.5 Ų48.560%0.60327%0.271SS*.SBendtrans-75.7-26.4177.200000113.4R345A324-R345 WeakPolarHBondContact O-CB 3.4Å; A324-R345 PolarHBondContact O-N 2.9Å
325D98Very high97.1Very high64 Ų6450.9 Ų50.934%0.34228%0.284SS..EExtended strand (participates in β ladder)trans-153.9170.2174.767.671.7000112.2K342 V343 T344D325-K342 VanDerWaalsContact CB-CE 3.48Å; D325-K342 WeakPolarHBondContact OD1-CE 3.21Å; D325-K342 IonicContact OD1-NZ 2.7Å; D325-K342 PolarHBondContact OD1-NZ 3.08Å; D325-K342 WeakPolarHBondContact OD2-CE 3.22Å; D325-K342 IonicContact OD2-NZ 2.74Å; D325-K342 PolarHBondContact OD2-NZ 2.8Å; D325-V343 WeakPolarHBondContact CA-O 3.38Å; D325-V343 WeakPolarHBondContact CB-O 3.3Å; D325-T344 HydrophobicContact CB-CG2 4.05Å
326H98.1Very high96.8Very high51 Ų5152.6 Ų52.624%0.23630%0.302CS..EExtended strand (participates in β ladder)trans-150.2158.7170.7-159.756.9000111.9L316 V319 L320 V343L316-H326 HydrophobicContact CD2-CB 3.93Å; V319-H326 HydrophobicContact CG1-CB 3.97Å; L320-H326 HydrophobicContact CD2-CB 4.31Å; H326-V343 PolarHBondContact N-O 3.42Å; H326-V343 PolarHBondContact O-N 3.35Å
327M97.9Very high96.6Very high78 Ų7855 Ų5538%0.38432%0.316SS..EExtended strand (participates in β ladder)trans-93.2103.7167.2-67.8-57-54.100109.4Q329 K340 A341 K342M327-Q329 PolarHBondContact O-N 2.96Å; M327-K340 HydrophobicContact CE-CD 4.36Å; M327-K340 HydrophobicContact CE-CG 3.72Å; M327-A341 CarbonylContact C-O 3.53Å; M327-A341 WeakPolarHBondContact CA-O 3.22Å; M327-A341 VanDerWaalsContact CE-C 3.49Å; M327-K342 HydrophobicContact CE-CB 4.26Å; M327-K342 HydrophobicContact SD-CB 3.56Å; M327-K342 VanDerWaalsContact SD-CB 3.56Å; M327-K342 HydrophobicContact SD-CD 4.4Å; M327-K342 HydrophobicContact SD-CG 3.93Å
328A97.6Very high96.5Very high0 Ų059.3 Ų59.30%034%0.34CS..EExtended strand (participates in β ladder)trans-62.1131.7166.900000109.2L283 E312 L316 F339 K340 A341 V343L283-A328 HydrophobicContact CD2-CB 3.98Å; E312-A328 HydrophobicContact CG-CB 4.24Å; E312-A328 WeakPolarHBondContact OE1-CA 3.41Å; L316-A328 HydrophobicContact CD1-CB 3.91Å; L316-A328 HydrophobicContact CD2-CB 4.16Å; L316-A328 HydrophobicContact CG-CB 4.45Å; A328-F339 HydrophobicContact CB-CE1 4.32Å; A328-K340 WeakPolarHBondContact O-CA 3.36Å; A328-A341 PolarHBondContact N-O 3.03Å; A328-A341 PolarHBondContact O-N 3.17Å; A328-V343 HydrophobicContact CB-CG2 4.37Å
329Q97.3Very high96.5Very high86 Ų8655.4 Ų55.440%0.40232%0.316SS..EExtended strand (participates in β ladder)trans-144.6126.6178.5-172.3172.9-49.200112E312 M327 F339E312-Q329 PolarHBondContact OE1-N 3.02Å; M327-Q329 PolarHBondContact O-N 2.96Å; Q329-F339 WeakPolarHBondContact CA-O 3.36Å
330I97.7Very high96.5Very high10 Ų1059.1 Ų59.15%0.05133%0.33CS..EExtended strand (participates in β ladder)trans-136.3113.4179.6-53.2176.8000109.5K308 L309 E312 L333 F339K308-I330 HydrophobicContact CB-CD1 4.43Å; K308-I330 HydrophobicContact CB-CG2 3.94Å; K308-I330 HydrophobicContact CD-CG2 3.73Å; K308-I330 HydrophobicContact CG-CG2 4.27Å; L309-I330 HydrophobicContact CD2-CD1 3.81Å; L309-I330 HydrophobicContact CG-CD1 4.23Å; E312-I330 HydrophobicContact CB-CD1 3.76Å; E312-I330 HydrophobicContact CB-CG1 4Å; E312-I330 HydrophobicContact CG-CD1 4.19Å; E312-I330 HydrophobicContact CG-CG1 4.03Å; I330-L333 HydrophobicContact CB-CB 4.45Å; I330-L333 HydrophobicContact CD1-CD1 4.29Å; I330-L333 HydrophobicContact CG2-CB 4.11Å; I330-L333 HydrophobicContact CG2-CD1 4.08Å; I330-F339 HydrophobicContact CB-CB 4.37Å; I330-F339 HydrophobicContact CB-CD1 4.4Å; I330-F339 HydrophobicContact CD1-CD1 4.06Å; I330-F339 HydrophobicContact CG1-CD1 4.17Å; I330-F339 PolarHBondContact N-O 3.26Å; I330-F339 PolarHBondContact O-N 3.21Å
331E96.2Very high96.5Very high141 Ų14159.5 Ų59.566%0.65933%0.333SS*.EExtended strand (participates in β ladder)trans-69.1137.1176-69.8162.1-166.800111.8K308 L333 D338K308-E331 PolarHBondContact NZ-O 3.06Å; E331-L333 VanDerWaalsContact C-N 3.34Å; E331-L333 PolarHBondContact O-N 3.47Å; E331-D338 WeakPolarHBondContact CA-OD1 3.27Å
332G95.3Very high96.5Very high21 Ų2163.6 Ų63.622%0.21635%0.347CS..EExtended strand (participates in β ladder)trans44.850.9179.100000113.6K308 M334 V337 D338K308-G332 VanDerWaalsContact NZ-C 3.34Å; K308-G332 PolarHBondContact NZ-O 3.38Å; G332-M334 PolarHBondContact O-N 3.5Å; G332-V337 CarbonylContact C-O 3.49Å; G332-D338 PolarHBondContact N-OD1 2.96Å
333L96.4Very high96.5Very high5 Ų559.8 Ų59.83%0.02632%0.316CS..EExtended strand (participates in β ladder)trans-56.8-49.3-171.7171.558.1000111.5F287 V299 A305 K308 L309 I330 E331 V337 F339F287-L333 HydrophobicContact CB-CD2 4.07Å; F287-L333 HydrophobicContact CD1-CD2 3.9Å; F287-L333 HydrophobicContact CD2-CD2 3.74Å; F287-L333 HydrophobicContact CE1-CD2 4.16Å; F287-L333 HydrophobicContact CE1-CG 4.35Å; F287-L333 HydrophobicContact CE2-CB 4.18Å; F287-L333 HydrophobicContact CE2-CD2 4Å; F287-L333 HydrophobicContact CE2-CG 4.37Å; F287-L333 HydrophobicContact CG-CD2 3.64Å; F287-L333 HydrophobicContact CZ-CB 4.24Å; F287-L333 HydrophobicContact CZ-CD2 4.18Å; F287-L333 HydrophobicContact CZ-CG 4.23Å; V299-L333 HydrophobicContact CG2-CD2 4.38Å; V299-L333 HydrophobicContact CG2-CG 4.33Å; A305-L333 HydrophobicContact CB-CD1 3.85Å; A305-L333 HydrophobicContact CB-CG 4.4Å; A305-L333 WeakPolarHBondContact CB-O 3.46Å; K308-L333 HydrophobicContact CB-CD1 3.9Å; K308-L333 HydrophobicContact CD-CD1 4.08Å; L309-L333 HydrophobicContact CD1-CD1 4.19Å; L309-L333 HydrophobicContact CD1-CD2 4.27Å; L309-L333 HydrophobicContact CD2-CD1 4.32Å; L309-L333 HydrophobicContact CD2-CD2 3.87Å; L309-L333 HydrophobicContact CG-CD1 3.83Å; L309-L333 HydrophobicContact CG-CD2 4.16Å; I330-L333 HydrophobicContact CB-CB 4.45Å; I330-L333 HydrophobicContact CD1-CD1 4.29Å; I330-L333 HydrophobicContact CG2-CB 4.11Å; I330-L333 HydrophobicContact CG2-CD1 4.08Å; E331-L333 VanDerWaalsContact C-N 3.34Å; E331-L333 PolarHBondContact O-N 3.47Å; L333-V337 PolarHBondContact N-O 2.93Å; L333-F339 HydrophobicContact CB-CB 3.97Å; L333-F339 HydrophobicContact CD2-CB 3.56Å; L333-F339 HydrophobicContact CD2-CD1 4.17Å; L333-F339 HydrophobicContact CD2-CG 3.88Å; L333-F339 HydrophobicContact CG-CB 4.41Å
334M95.1Very high96.6Very high8 Ų858 Ų584%0.03931%0.309CS..EExtended strand (participates in β ladder)trans-153.3144.2172.4-172.5166.281.500109.8F287 K297 V299 N302 A305 G332 D336 V337F287-M334 HydrophobicContact CE1-CB 3.94Å; F287-M334 HydrophobicContact CE1-CE 4.4Å; F287-M334 HydrophobicContact CZ-CB 4.03Å; K297-M334 HydrophobicContact CB-CE 4.14Å; K297-M334 WeakPolarHBondContact O-CE 3.23Å; V299-M334 HydrophobicContact CB-CE 4.3Å; V299-M334 HydrophobicContact CG2-CB 4.48Å; V299-M334 HydrophobicContact CG2-SD 4.36Å; N302-M334 HydrophobicContact CB-SD 3.56Å; N302-M334 VanDerWaalsContact CB-SD 3.56Å; N302-M334 WeakPolarHBondContact ND2-CG 3.3Å; N302-M334 PolarHBondContact ND2-SD 2.84Å; N302-M334 VanDerWaalsContact ND2-SD 3.43Å; A305-M334 HydrophobicContact CB-CB 4.29Å; G332-M334 PolarHBondContact O-N 3.5Å; M334-D336 PolarHBondContact O-N 3.4Å; M334-V337 WeakPolarHBondContact O-CB 3.41Å; M334-V337 PolarHBondContact O-N 3.03Å
335D91.6Very high96.6Very high94 Ų9457.4 Ų57.450%0.50329%0.291SS..THydrogen-bonded Turntrans52.637.2-178.4-40.9-39.7000113.4R291 V337R291-D335 IonicContact CZ-OD2 3.23Å; R291-D335 VanDerWaalsContact CZ-OD2 3.23Å; R291-D335 IonicContact NH1-OD2 3.84Å; R291-D335 PolarHBondContact NH1-OD2 2.94Å; R291-D335 IonicContact NH2-OD2 2.78Å; R291-D335 PolarHBondContact NH2-OD2 2.87Å; D335-V337 PolarHBondContact O-N 3.2Å
336D91.6Very high96.6Very high154 Ų15458.6 Ų58.682%0.82430%0.3SS*.THydrogen-bonded Turntrans55.718.5-174.8-54.5-41.7000115.1M334M334-D336 PolarHBondContact O-N 3.4Å
337V93.9Very high96.6Very high50 Ų5057.6 Ų57.630%0.30330%0.296SS..EExtended strand (participates in β ladder)trans-87.1121.2172.4-173.40000110.2F287 G332 L333 M334 D335F287-V337 HydrophobicContact CE2-CB 4.14Å; F287-V337 HydrophobicContact CE2-CG1 3.96Å; F287-V337 HydrophobicContact CZ-CB 4.2Å; F287-V337 HydrophobicContact CZ-CG1 4.45Å; G332-V337 CarbonylContact C-O 3.49Å; L333-V337 PolarHBondContact N-O 2.93Å; M334-V337 WeakPolarHBondContact O-CB 3.41Å; M334-V337 PolarHBondContact O-N 3.03Å; D335-V337 PolarHBondContact O-N 3.2Å
338D96.1Very high96.7Very high107 Ų10754 Ų5457%0.57228%0.278SS*.EExtended strand (participates in β ladder)trans-66.1141.8169.7-68-23.9000111.5E331 G332E331-D338 WeakPolarHBondContact CA-OD1 3.27Å; G332-D338 PolarHBondContact N-OD1 2.96Å
339F97.6Very high96.7Very high0 Ų055.9 Ų55.90%029%0.286CS..EExtended strand (participates in β ladder)trans-108.9132.6172.5171.6-116.1000110.7L283 L286 F287 L309 A328 Q329 I330 L333 A341L283-F339 HydrophobicContact CB-CE1 4.01Å; L283-F339 HydrophobicContact CB-CZ 4.07Å; L283-F339 HydrophobicContact CD1-CE1 4.31Å; L283-F339 HydrophobicContact CD2-CE1 3.88Å; L283-F339 HydrophobicContact CD2-CZ 3.88Å; L283-F339 HydrophobicContact CG-CE1 4.27Å; L283-F339 HydrophobicContact CG-CZ 4.49Å; L286-F339 HydrophobicContact CB-CE2 3.98Å; L286-F339 HydrophobicContact CB-CZ 4.16Å; F287-F339 HydrophobicContact CB-CD2 3.7Å; F287-F339 HydrophobicContact CB-CE2 3.94Å; F287-F339 HydrophobicContact CB-CG 4.36Å; F287-F339 HydrophobicContact CD2-CB 3.79Å; F287-F339 AromaticContact CD2-CD2 3.8Å; F287-F339 HydrophobicContact CD2-CD2 3.8Å; F287-F339 HydrophobicContact CD2-CG 4.11Å; F287-F339 HydrophobicContact CE2-CB 4.22Å; F287-F339 HydrophobicContact CG-CD2 4.21Å; L309-F339 HydrophobicContact CD2-CD1 4.41Å; L309-F339 HydrophobicContact CD2-CE1 4.31Å; A328-F339 HydrophobicContact CB-CE1 4.32Å; Q329-F339 WeakPolarHBondContact CA-O 3.36Å; I330-F339 HydrophobicContact CB-CB 4.37Å; I330-F339 HydrophobicContact CB-CD1 4.4Å; I330-F339 HydrophobicContact CD1-CD1 4.06Å; I330-F339 HydrophobicContact CG1-CD1 4.17Å; I330-F339 PolarHBondContact N-O 3.26Å; I330-F339 PolarHBondContact O-N 3.21Å; L333-F339 HydrophobicContact CB-CB 3.97Å; L333-F339 HydrophobicContact CD2-CB 3.56Å; L333-F339 HydrophobicContact CD2-CD1 4.17Å; L333-F339 HydrophobicContact CD2-CG 3.88Å; L333-F339 HydrophobicContact CG-CB 4.41Å; F339-A341 HydrophobicContact CE1-CB 4.46Å; F339-A341 HydrophobicContact CE2-CB 3.85Å; F339-A341 HydrophobicContact CZ-CB 3.62Å
340K97.4Very high96.7Very high111 Ų11158.4 Ų58.448%0.48330%0.298SS..EExtended strand (participates in β ladder)trans-144.5130.2172.8-170.6163.8-173.8152.50110.5Q290 M327 A328Q290-K340 PolarHBondContact NE2-O 2.75Å; M327-K340 HydrophobicContact CE-CD 4.36Å; M327-K340 HydrophobicContact CE-CG 3.72Å; A328-K340 WeakPolarHBondContact O-CA 3.36Å
341A97.8Very high96.8Very high9 Ų960.9 Ų60.97%0.07431%0.311CS..EExtended strand (participates in β ladder)trans-149.2147.2178.100000111.3L286 M327 A328 F339L286-A341 HydrophobicContact CD1-CB 4.05Å; M327-A341 CarbonylContact C-O 3.53Å; M327-A341 WeakPolarHBondContact CA-O 3.22Å; M327-A341 VanDerWaalsContact CE-C 3.49Å; A328-A341 PolarHBondContact N-O 3.03Å; A328-A341 PolarHBondContact O-N 3.17Å; F339-A341 HydrophobicContact CE1-CB 4.46Å; F339-A341 HydrophobicContact CE2-CB 3.85Å; F339-A341 HydrophobicContact CZ-CB 3.62Å
342K97.9Very high96.9Very high112 Ų11254.2 Ų54.249%0.48728%0.28SS..EExtended strand (participates in β ladder)trans-82.6134.2166.5-170.5167.8179.5164.80108.6D325 M327D325-K342 VanDerWaalsContact CB-CE 3.48Å; D325-K342 WeakPolarHBondContact OD1-CE 3.21Å; D325-K342 IonicContact OD1-NZ 2.7Å; D325-K342 PolarHBondContact OD1-NZ 3.08Å; D325-K342 WeakPolarHBondContact OD2-CE 3.22Å; D325-K342 IonicContact OD2-NZ 2.74Å; D325-K342 PolarHBondContact OD2-NZ 2.8Å; M327-K342 HydrophobicContact CE-CB 4.26Å; M327-K342 HydrophobicContact SD-CB 3.56Å; M327-K342 VanDerWaalsContact SD-CB 3.56Å; M327-K342 HydrophobicContact SD-CD 4.4Å; M327-K342 HydrophobicContact SD-CG 3.93Å
343V98.2Very high97Very high0 Ų055.5 Ų55.50%029%0.289CS..EExtended strand (participates in β ladder)trans-127.8136.5173-176.50000108.2L279 L283 L316 L320 D325 H326 A328 E347L279-V343 HydrophobicContact CD2-CG1 4.19Å; L283-V343 HydrophobicContact CD2-CG2 3.8Å; L316-V343 HydrophobicContact CD1-CG2 4.17Å; L316-V343 HydrophobicContact CD2-CB 4.47Å; L320-V343 HydrophobicContact CD1-CG1 4.03Å; D325-V343 WeakPolarHBondContact CA-O 3.38Å; D325-V343 WeakPolarHBondContact CB-O 3.3Å; H326-V343 PolarHBondContact N-O 3.42Å; H326-V343 PolarHBondContact O-N 3.35Å; A328-V343 HydrophobicContact CB-CG2 4.37Å; V343-E347 WeakPolarHBondContact CA-OE2 3.33Å
344T98.6Very high97.1Very high45 Ų4558.4 Ų58.428%0.27630%0.304SS..EExtended strand (participates in β ladder)trans-107.2159.1-17969.40000112.3D325 V346 E347 F348D325-T344 HydrophobicContact CB-CG2 4.05Å; T344-V346 VanDerWaalsContact C-N 3.29Å; T344-E347 PolarHBondContact N-OE2 2.73Å; T344-E347 VanDerWaalsContact OG1-CB 3.23Å; T344-E347 WeakPolarHBondContact OG1-CB 3.38Å; T344-E347 PolarHBondContact OG1-N 2.86Å; T344-F348 WeakPolarHBondContact O-CB 3.15Å; T344-F348 PolarHBondContact O-N 3.24Å
345R98.6Very high97.3Very high59 Ų5958 Ų5822%0.22330%0.303CS..Hα-helixtrans-60.5-41.3170.7-179.6-175.4-62.5171.71.9111L320 S321 A322 N323 A324 F348 E349L320-R345 VanDerWaalsContact O-CZ 3.31Å; L320-R345 PolarHBondContact O-NE 3.13Å; L320-R345 PolarHBondContact O-NH2 2.72Å; S321-R345 PolarHBondContact O-NH2 2.97Å; A322-R345 PolarHBondContact O-NH2 2.8Å; N323-R345 VanDerWaalsContact C-NH2 3.31Å; N323-R345 PolarHBondContact O-NE 2.96Å; N323-R345 PolarHBondContact O-NH2 2.87Å; A324-R345 WeakPolarHBondContact O-CB 3.4Å; A324-R345 PolarHBondContact O-N 2.9Å; R345-F348 WeakPolarHBondContact O-CB 3.38Å; R345-F348 PolarHBondContact O-N 3.07Å; R345-E349 WeakPolarHBondContact CD-OE1 3.14Å; R345-E349 HydrophobicContact CG-CG 4.2Å; R345-E349 VanDerWaalsContact CG-OE1 3.24Å; R345-E349 WeakPolarHBondContact CG-OE1 3.49Å; R345-E349 WeakPolarHBondContact O-CB 3.38Å; R345-E349 VanDerWaalsContact O-CG 3.32Å; R345-E349 WeakPolarHBondContact O-CG 3.45Å; R345-E349 PolarHBondContact O-N 3.07Å
346V98.4Very high97.6Very high89 Ų8954 Ų5454%0.53928%0.28SS..Hα-helixtrans-60.9-50.2179.6-177.90000110.6T344 F348 E349 E350T344-V346 VanDerWaalsContact C-N 3.29Å; V346-F348 VanDerWaalsContact C-N 3.33Å; V346-F348 PolarHBondContact O-N 3.1Å; V346-E349 PolarHBondContact O-N 3.05Å; V346-E349 VanDerWaalsContact O-N 3.11Å; V346-E350 HydrophobicContact CG1-CG 4.42Å; V346-E350 WeakPolarHBondContact O-CB 3.35Å; V346-E350 WeakPolarHBondContact O-CG 3.43Å; V346-E350 PolarHBondContact O-N 3.47Å
347E98.1Very high97.9Very high31 Ų3154.3 Ų54.315%0.14528%0.277CS..Hα-helixtrans-59.1-41.3174.9176.8-178.1-153.800112.4R282 V343 T344 E349 L351R282-E347 IonicContact CZ-OE1 3.2Å; R282-E347 IonicContact NE-OE1 2.87Å; R282-E347 PolarHBondContact NE-OE1 2.73Å; R282-E347 IonicContact NH2-OE1 3.2Å; R282-E347 PolarHBondContact NH2-OE1 2.75Å; V343-E347 WeakPolarHBondContact CA-OE2 3.33Å; T344-E347 PolarHBondContact N-OE2 2.73Å; T344-E347 VanDerWaalsContact OG1-CB 3.23Å; T344-E347 WeakPolarHBondContact OG1-CB 3.38Å; T344-E347 PolarHBondContact OG1-N 2.86Å; E347-E349 VanDerWaalsContact C-N 3.34Å; E347-L351 HydrophobicContact CG-CD1 4.38Å; E347-L351 WeakPolarHBondContact O-CB 3.08Å; E347-L351 WeakPolarHBondContact O-CD1 3.47Å; E347-L351 WeakPolarHBondContact O-CG 3.2Å; E347-L351 PolarHBondContact O-N 2.88Å
348F98.6Very high98.2Very high2 Ų255.7 Ų55.71%0.00928%0.277CS..Hα-helixtrans-62.5-40.4174.2167.5-123000112.4M275 L279 K317 L320 T344 R345 V346 C352 V389M275-F348 HydrophobicContact CB-CE2 3.91Å; M275-F348 HydrophobicContact CB-CZ 4.07Å; M275-F348 HydrophobicContact CG-CE2 4.47Å; M275-F348 HydrophobicContact CG-CZ 4.35Å; M275-F348 HydrophobicContact SD-CZ 4.21Å; L279-F348 HydrophobicContact CD1-CD2 3.6Å; L279-F348 HydrophobicContact CD1-CE2 3.64Å; L279-F348 HydrophobicContact CD1-CG 4.45Å; L279-F348 HydrophobicContact CD2-CB 4.27Å; L279-F348 HydrophobicContact CD2-CD2 3.72Å; L279-F348 HydrophobicContact CD2-CG 4.33Å; L279-F348 HydrophobicContact CG-CD2 3.62Å; L279-F348 HydrophobicContact CG-CE2 3.96Å; K317-F348 HydrophobicContact CG-CZ 4.22Å; L320-F348 HydrophobicContact CD1-CB 3.93Å; L320-F348 HydrophobicContact CD1-CG 4.31Å; T344-F348 WeakPolarHBondContact O-CB 3.15Å; T344-F348 PolarHBondContact O-N 3.24Å; R345-F348 WeakPolarHBondContact O-CB 3.38Å; R345-F348 PolarHBondContact O-N 3.07Å; V346-F348 VanDerWaalsContact C-N 3.33Å; V346-F348 PolarHBondContact O-N 3.1Å; F348-C352 VanDerWaalsContact CE2-SG 3.52Å; F348-C352 PolarHBondContact O-N 2.94Å; F348-C352 PolarHBondContact O-SG 3.23Å; F348-V389 HydrophobicContact CE1-CG1 3.97Å; F348-V389 HydrophobicContact CE1-CG2 4.35Å; F348-V389 HydrophobicContact CZ-CG2 4.48Å
349E98.3Very high98.3Very high39 Ų3950.6 Ų50.618%0.18225%0.25CC..Hα-helixtrans-74.9-37-179.2-73.3171.5176.600112R345 V346 E347 C352 A353 F356 R391R345-E349 WeakPolarHBondContact CD-OE1 3.14Å; R345-E349 HydrophobicContact CG-CG 4.2Å; R345-E349 VanDerWaalsContact CG-OE1 3.24Å; R345-E349 WeakPolarHBondContact CG-OE1 3.49Å; R345-E349 WeakPolarHBondContact O-CB 3.38Å; R345-E349 VanDerWaalsContact O-CG 3.32Å; R345-E349 WeakPolarHBondContact O-CG 3.45Å; R345-E349 PolarHBondContact O-N 3.07Å; V346-E349 PolarHBondContact O-N 3.05Å; V346-E349 VanDerWaalsContact O-N 3.11Å; E347-E349 VanDerWaalsContact C-N 3.34Å; E349-C352 CarbonylContact O-C 3.48Å; E349-C352 PolarHBondContact O-N 3Å; E349-A353 PolarHBondContact O-N 2.62Å; E349-A353 VanDerWaalsContact O-N 3.11Å; E349-F356 HydrophobicContact CB-CE2 4.02Å; E349-F356 HydrophobicContact CG-CE2 4.12Å; E349-F356 HydrophobicContact CG-CZ 4.25Å; E349-F356 WeakPolarHBondContact O-CE2 3.43Å; E349-R391 HydrophobicContact CG-CB 3.9Å; E349-R391 HydrophobicContact CG-CG 4.31Å
350E98.4Very high98.3Very high140 Ų14051.7 Ų51.765%0.65426%0.257SS*.Hα-helixtrans-60.1-45.5170.8-74.6173.3172.600111.7V346 C352 A353V346-E350 HydrophobicContact CG1-CG 4.42Å; V346-E350 WeakPolarHBondContact O-CB 3.35Å; V346-E350 WeakPolarHBondContact O-CG 3.43Å; V346-E350 PolarHBondContact O-N 3.47Å; E350-C352 PolarHBondContact O-N 3.01Å; E350-A353 PolarHBondContact O-N 3.05Å
351L98.4Very high98.4Very high62 Ų6247.4 Ų47.433%0.32524%0.244SC..Hα-helixtrans-60-27.8175.6-74.6167.1000113.2R278 R282 E347R278-L351 HydrophobicContact CB-CB 4.41Å; R278-L351 WeakPolarHBondContact CD-O 3.47Å; R278-L351 PolarHBondContact NE-O 3.28Å; R278-L351 VanDerWaalsContact NE-O 3.13Å; R282-L351 HydrophobicContact CB-CD1 3.84Å; R282-L351 HydrophobicContact CG-CD1 3.94Å; E347-L351 HydrophobicContact CG-CD1 4.38Å; E347-L351 WeakPolarHBondContact O-CB 3.08Å; E347-L351 WeakPolarHBondContact O-CD1 3.47Å; E347-L351 WeakPolarHBondContact O-CG 3.2Å; E347-L351 PolarHBondContact O-N 2.88Å
352C98.5Very high98.4Very high0 Ų047.1 Ų47.10%024%0.241CC..THydrogen-bonded Turntrans-10711.9-174.7-58.40000113.8R278 F348 E349 E350 D354 L355 F356R278-C352 VanDerWaalsContact CD-SG 3.54Å; F348-C352 VanDerWaalsContact CE2-SG 3.52Å; F348-C352 PolarHBondContact O-N 2.94Å; F348-C352 PolarHBondContact O-SG 3.23Å; E349-C352 CarbonylContact O-C 3.48Å; E349-C352 PolarHBondContact O-N 3Å; E350-C352 PolarHBondContact O-N 3.01Å; C352-D354 VanDerWaalsContact C-N 3.28Å; C352-D354 PolarHBondContact O-N 3.26Å; C352-L355 HydrophobicContact CB-CD1 4.36Å; C352-L355 WeakPolarHBondContact O-CB 3.41Å; C352-L355 PolarHBondContact O-N 3.25Å; C352-F356 HydrophobicContact CB-CD2 4.32Å; C352-F356 HydrophobicContact CB-CE1 4.44Å; C352-F356 HydrophobicContact CB-CE2 3.6Å; C352-F356 HydrophobicContact CB-CZ 3.66Å; C352-F356 VanDerWaalsContact O-CD2 3.26Å; C352-F356 WeakPolarHBondContact O-CD2 3.16Å; C352-F356 PolarHBondContact O-N 3.43Å
353A98.4Very high98.4Very high48 Ų4841.9 Ų41.940%0.39722%0.219SC..Hα-helixtrans-52.7-43.4-174.600000113.2E349 E350 L355 F356 E357E349-A353 PolarHBondContact O-N 2.62Å; E349-A353 VanDerWaalsContact O-N 3.11Å; E350-A353 PolarHBondContact O-N 3.05Å; A353-L355 VanDerWaalsContact C-N 3.25Å; A353-L355 PolarHBondContact O-N 2.85Å; A353-F356 PolarHBondContact O-N 3.39Å; A353-F356 VanDerWaalsContact O-N 3.12Å; A353-E357 PolarHBondContact O-N 2.86Å; A353-E357 VanDerWaalsContact O-N 3.12Å
354D98.3Very high98.4Very high67 Ų6748.1 Ų48.136%0.35825%0.248SC..Hα-helixtrans-64.4-26.4178.876.2-67.2000113.7R278 C352 R358R278-D354 IonicContact CZ-OD1 3.84Å; R278-D354 IonicContact CZ-OD2 3.23Å; R278-D354 IonicContact NE-OD1 3.35Å; R278-D354 PolarHBondContact NE-OD1 3.38Å; R278-D354 IonicContact NH2-OD1 2.7Å; R278-D354 PolarHBondContact NH2-OD1 3.1Å; R278-D354 IonicContact NH2-OD2 2.67Å; R278-D354 PolarHBondContact NH2-OD2 3.35Å; C352-D354 VanDerWaalsContact C-N 3.28Å; C352-D354 PolarHBondContact O-N 3.26Å; D354-R358 VanDerWaalsContact O-CD 3.27Å; D354-R358 WeakPolarHBondContact O-CD 3.31Å
355L98.5Very high98.4Very high0 Ų048.8 Ų48.80%025%0.248CC..Hα-helixtrans-77.4-37.9174.5-57.4-176000111L270 E274 M275 C352 A353 R358L270-L355 HydrophobicContact CD1-CB 3.72Å; L270-L355 HydrophobicContact CD1-CD2 4.19Å; L270-L355 HydrophobicContact CD1-CG 4.47Å; L270-L355 VanDerWaalsContact CD1-O 3.28Å; L270-L355 WeakPolarHBondContact CD1-O 3.37Å; E274-L355 HydrophobicContact CB-CD1 4.02Å; E274-L355 HydrophobicContact CG-CD1 4.02Å; E274-L355 HydrophobicContact CG-CD2 3.84Å; M275-L355 HydrophobicContact CG-CD1 3.78Å; C352-L355 HydrophobicContact CB-CD1 4.36Å; C352-L355 WeakPolarHBondContact O-CB 3.41Å; C352-L355 PolarHBondContact O-N 3.25Å; A353-L355 VanDerWaalsContact C-N 3.25Å; A353-L355 PolarHBondContact O-N 2.85Å; L355-R358 PolarHBondContact O-N 3.47Å
356F98.5Very high98.4Very high8 Ų846 Ų464%0.03524%0.237CC..Hα-helixtrans-70.2-33179-55.4-49000112.4M275 E349 C352 A353 R358 V359 V389 R391 V392 V395M275-F356 HydrophobicContact CE-CD1 4.35Å; M275-F356 HydrophobicContact CE-CE1 3.65Å; M275-F356 HydrophobicContact CE-CZ 4.4Å; E349-F356 HydrophobicContact CB-CE2 4.02Å; E349-F356 HydrophobicContact CG-CE2 4.12Å; E349-F356 HydrophobicContact CG-CZ 4.25Å; E349-F356 WeakPolarHBondContact O-CE2 3.43Å; C352-F356 HydrophobicContact CB-CD2 4.32Å; C352-F356 HydrophobicContact CB-CE1 4.44Å; C352-F356 HydrophobicContact CB-CE2 3.6Å; C352-F356 HydrophobicContact CB-CZ 3.66Å; C352-F356 VanDerWaalsContact O-CD2 3.26Å; C352-F356 WeakPolarHBondContact O-CD2 3.16Å; C352-F356 PolarHBondContact O-N 3.43Å; A353-F356 PolarHBondContact O-N 3.39Å; A353-F356 VanDerWaalsContact O-N 3.12Å; F356-R358 PolarHBondContact O-N 2.86Å; F356-R358 VanDerWaalsContact O-N 3.15Å; F356-V359 WeakPolarHBondContact O-CB 3.47Å; F356-V359 PolarHBondContact O-N 3.5Å; F356-V389 HydrophobicContact CE1-CG1 4.2Å; F356-V389 HydrophobicContact CZ-CG1 4.27Å; F356-R391 HydrophobicContact CB-CG 4.42Å; F356-R391 HydrophobicContact CD1-CB 4.33Å; F356-R391 HydrophobicContact CD1-CG 4.02Å; F356-R391 HydrophobicContact CD2-CB 4.31Å; F356-R391 HydrophobicContact CD2-CG 3.44Å; F356-R391 VanDerWaalsContact CD2-CG 3.44Å; F356-R391 HydrophobicContact CE1-CB 4.01Å; F356-R391 HydrophobicContact CE1-CG 4.11Å; F356-R391 HydrophobicContact CE2-CB 3.98Å; F356-R391 HydrophobicContact CE2-CG 3.53Å; F356-R391 HydrophobicContact CG-CB 4.49Å; F356-R391 HydrophobicContact CG-CG 3.71Å; F356-R391 HydrophobicContact CZ-CB 3.82Å; F356-R391 HydrophobicContact CZ-CG 3.88Å; F356-V392 HydrophobicContact CD1-CG2 3.95Å; F356-V392 HydrophobicContact CE1-CG2 3.71Å; F356-V395 HydrophobicContact CB-CG2 4.38Å
357E98.4Very high98.4Very high162 Ų16243 Ų4376%0.75722%0.218SC*.THydrogen-bonded Turntrans-59.2-23.5172-70.9-177173.500113.2A353 P360A353-E357 PolarHBondContact O-N 2.86Å; A353-E357 VanDerWaalsContact O-N 3.12Å; E357-P360 WeakPolarHBondContact O-CD 3.18Å
358R98.4Very high98.4Very high79 Ų7948 Ų4830%0.29824%0.241SC..THydrogen-bonded Turntrans-89.2-16.1179.8-65.8158.360.51772114.2D267 T269 L270 D354 L355 F356 P360 G361 P362D267-R358 IonicContact OD1-NH2 3.84Å; D267-R358 PolarHBondContact OD1-NH2 2.65Å; D267-R358 IonicContact OD2-CZ 2.64Å; D267-R358 VanDerWaalsContact OD2-CZ 3.26Å; D267-R358 IonicContact OD2-NE 2.82Å; D267-R358 PolarHBondContact OD2-NE 2.89Å; D267-R358 IonicContact OD2-NH2 3.31Å; D267-R358 PolarHBondContact OD2-NH2 2.73Å; T269-R358 PolarHBondContact OG1-NH2 3.39Å; L270-R358 HydrophobicContact CD1-CB 4.42Å; L270-R358 HydrophobicContact CD2-CB 3.86Å; D354-R358 VanDerWaalsContact O-CD 3.27Å; D354-R358 WeakPolarHBondContact O-CD 3.31Å; L355-R358 PolarHBondContact O-N 3.47Å; F356-R358 PolarHBondContact O-N 2.86Å; F356-R358 VanDerWaalsContact O-N 3.15Å; R358-P360 VanDerWaalsContact C-CD 3.44Å; R358-P360 VanDerWaalsContact C-N 3.33Å; R358-G361 PolarHBondContact O-N 3.44Å; R358-P362 WeakPolarHBondContact O-CD 3.35Å
359V98.7Very high98.4Very high0 Ų048.4 Ų48.40%025%0.245CC..THydrogen-bonded Turntrans-51.2-39.8179.3163.80000113.7Y231 L270 F356 G361 V392 V395 L396Y231-V359 WeakPolarHBondContact OH-CG1 2.91Å; Y231-V359 PolarHBondContact OH-O 3.15Å; L270-V359 HydrophobicContact CD2-CG2 4.48Å; F356-V359 WeakPolarHBondContact O-CB 3.47Å; F356-V359 PolarHBondContact O-N 3.5Å; V359-G361 VanDerWaalsContact C-N 3.32Å; V359-G361 PolarHBondContact O-N 3.14Å; V359-V392 HydrophobicContact CG1-CG1 4.45Å; V359-V392 HydrophobicContact CG2-CG1 4.21Å; V359-V395 HydrophobicContact CB-CG1 4.07Å; V359-V395 HydrophobicContact CG1-CB 4.35Å; V359-V395 HydrophobicContact CG1-CG1 4.07Å; V359-L396 HydrophobicContact CG1-CB 3.88Å; V359-L396 HydrophobicContact CG1-CD1 4.39Å
360P98.6Very high98.4Very high23 Ų2347.5 Ų47.515%0.14924%0.244CC..Hα-helixtrans-71.1-19.8176.6-21.135.4000115.1E357 R358 V363 Q364 V395 A399E357-P360 WeakPolarHBondContact O-CD 3.18Å; R358-P360 VanDerWaalsContact C-CD 3.44Å; R358-P360 VanDerWaalsContact C-N 3.33Å; P360-V363 WeakPolarHBondContact O-CB 3.4Å; P360-V363 PolarHBondContact O-N 2.98Å; P360-Q364 WeakPolarHBondContact O-CG 3.38Å; P360-Q364 PolarHBondContact O-N 3.19Å; P360-Q364 VanDerWaalsContact O-N 3.11Å; P360-V395 HydrophobicContact CG-CG1 4.04Å; P360-A399 HydrophobicContact CB-CB 3.88Å; P360-A399 HydrophobicContact CG-CB 3.96Å
361G98.2Very high98.3Very high21 Ų2149.8 Ų49.822%0.21625%0.254CS..Hα-helixtrans-59.3-51.6-171.200000114R358 V359 V363 Q364 Q365R358-G361 PolarHBondContact O-N 3.44Å; V359-G361 VanDerWaalsContact C-N 3.32Å; V359-G361 PolarHBondContact O-N 3.14Å; G361-V363 VanDerWaalsContact C-N 3.27Å; G361-V363 PolarHBondContact O-N 3.41Å; G361-Q364 PolarHBondContact O-N 2.73Å; G361-Q365 WeakPolarHBondContact O-CG 3.4Å; G361-Q365 PolarHBondContact O-N 3.45Å
362P98.5Very high98.3Very high2 Ų248.2 Ų48.21%0.01325%0.246CC..Hα-helixtrans-57.7-35.6174.8-29.538.3000113.7Y231 T238 C240 G265 D267 R358 A366Y231-P362 HydrophobicContact CE2-CB 4.36Å; T238-P362 HydrophobicContact CG2-CB 4.28Å; T238-P362 HydrophobicContact CG2-CG 3.81Å; C240-P362 HydrophobicContact CB-CB 3.71Å; C240-P362 WeakPolarHBondContact CB-O 2.99Å; G265-P362 WeakPolarHBondContact CA-O 3.33Å; D267-P362 HydrophobicContact CB-CG 4.25Å; R358-P362 WeakPolarHBondContact O-CD 3.35Å; P362-A366 VanDerWaalsContact O-CB 3.31Å; P362-A366 WeakPolarHBondContact O-CB 3.47Å; P362-A366 PolarHBondContact O-N 3.22Å
363V98.8Very high98.2Very high3 Ų350.7 Ų50.72%0.01826%0.263CS..Hα-helixtrans-63.9-47.8176.2178.40000110.8M229 Y231 P360 G361 A366 L367 L396 V400M229-V363 HydrophobicContact CE-CG1 3.92Å; M229-V363 HydrophobicContact SD-CG1 3.97Å; M229-V363 HydrophobicContact SD-CG2 4.37Å; Y231-V363 HydrophobicContact CD2-CG2 3.8Å; Y231-V363 HydrophobicContact CE2-CG2 3.85Å; P360-V363 WeakPolarHBondContact O-CB 3.4Å; P360-V363 PolarHBondContact O-N 2.98Å; G361-V363 VanDerWaalsContact C-N 3.27Å; G361-V363 PolarHBondContact O-N 3.41Å; V363-A366 PolarHBondContact O-N 2.89Å; V363-L367 HydrophobicContact CG1-CD1 4Å; V363-L367 WeakPolarHBondContact O-CG 3.47Å; V363-L367 PolarHBondContact O-N 2.87Å; V363-L396 HydrophobicContact CG2-CD1 3.69Å; V363-V400 HydrophobicContact CG1-CG1 4.16Å; V363-V400 HydrophobicContact CG2-CG1 4.31Å
364Q98.4Very high98.2Very high130 Ų13050.6 Ų50.661%0.60726%0.256SS*.Hα-helixtrans-62.5-44.9179.9-66.5169.71000111.6P360 G361 A366 L367 Q368P360-Q364 WeakPolarHBondContact O-CG 3.38Å; P360-Q364 PolarHBondContact O-N 3.19Å; P360-Q364 VanDerWaalsContact O-N 3.11Å; G361-Q364 PolarHBondContact O-N 2.73Å; Q364-A366 PolarHBondContact O-N 2.95Å; Q364-L367 PolarHBondContact O-N 3.37Å; Q364-Q368 VanDerWaalsContact O-CB 3.29Å; Q364-Q368 WeakPolarHBondContact O-CB 3.31Å; Q364-Q368 PolarHBondContact O-N 2.85Å
365Q98.3Very high98.1Very high60 Ų6054.3 Ų54.328%0.2828%0.276SS..Hα-helixtrans-62.7-38.5175.1-70.617619.100112.8G265 F266 G361 S369G265-Q365 VanDerWaalsContact CA-CB 3.47Å; F266-Q365 PolarHBondContact O-NE2 3.42Å; F266-Q365 PolarHBondContact O-OE1 2.86Å; G361-Q365 WeakPolarHBondContact O-CG 3.4Å; G361-Q365 PolarHBondContact O-N 3.45Å; Q365-S369 WeakPolarHBondContact O-CB 3.06Å; Q365-S369 PolarHBondContact O-N 2.9Å; Q365-S369 PolarHBondContact O-OG 3.26Å
366A98.7Very high98Very high0 Ų058.7 Ų58.70%030%0.296CS..Hα-helixtrans-66.5-46.717800000111.5C240 I242 G263 P362 V363 Q364 S369 A370C240-A366 HydrophobicContact CB-CB 4.07Å; I242-A366 HydrophobicContact CD1-CB 4.03Å; I242-A366 HydrophobicContact CG1-CB 4.16Å; G263-A366 WeakPolarHBondContact CA-O 3.42Å; P362-A366 VanDerWaalsContact O-CB 3.31Å; P362-A366 WeakPolarHBondContact O-CB 3.47Å; P362-A366 PolarHBondContact O-N 3.22Å; V363-A366 PolarHBondContact O-N 2.89Å; Q364-A366 PolarHBondContact O-N 2.95Å; A366-S369 PolarHBondContact O-N 3.12Å; A366-S369 PolarHBondContact O-OG 2.93Å; A366-S369 VanDerWaalsContact O-OG 3.1Å; A366-A370 WeakPolarHBondContact O-CB 3.28Å; A366-A370 PolarHBondContact O-N 2.82Å
367L98.6Very high98Very high25 Ų2558.4 Ų58.413%0.13130%0.295CS..Hα-helixtrans-61.2-46.6175.2-71.3166.7000111.6M229 I242 V363 Q364 S369 A370 E371 M372 L374 I377M229-L367 HydrophobicContact CE-CD2 4.07Å; M229-L367 HydrophobicContact CE-CG 4.08Å; I242-L367 HydrophobicContact CD1-CD2 3.78Å; I242-L367 HydrophobicContact CD1-CG 4.12Å; V363-L367 HydrophobicContact CG1-CD1 4Å; V363-L367 WeakPolarHBondContact O-CG 3.47Å; V363-L367 PolarHBondContact O-N 2.87Å; Q364-L367 PolarHBondContact O-N 3.37Å; L367-S369 VanDerWaalsContact C-N 3.33Å; L367-S369 PolarHBondContact O-N 3.14Å; L367-A370 PolarHBondContact O-N 3.44Å; L367-E371 PolarHBondContact O-N 3.04Å; L367-E371 VanDerWaalsContact O-N 3.11Å; L367-M372 PolarHBondContact O-N 2.96Å; L367-M372 VanDerWaalsContact O-N 3.15Å; L367-L374 HydrophobicContact CD1-CB 4.26Å; L367-L374 HydrophobicContact CD1-CD1 4.21Å; L367-I377 HydrophobicContact CD2-CD1 4.31Å; L367-I377 HydrophobicContact CD2-CG1 4.04Å
368Q97.9Very high97.9Very high137 Ų13755.9 Ų55.964%0.6428%0.283SS*.Hα-helixtrans-61.3-39.2178.4-170.3-169.831.300112.5Q364 E371Q364-Q368 VanDerWaalsContact O-CB 3.29Å; Q364-Q368 WeakPolarHBondContact O-CB 3.31Å; Q364-Q368 PolarHBondContact O-N 2.85Å; Q368-E371 PolarHBondContact O-N 3.33Å
369S97.4Very high97.9Very high11 Ų1154.1 Ų54.18%0.07728%0.278CS..Hα-helixtrans-78.4-25.6178.653.70000113.7G263 V264 Q365 A366 L367 E371 M473G263-S369 WeakPolarHBondContact CA-OG 3.37Å; V264-S369 PolarHBondContact N-OG 3.01Å; V264-S369 PolarHBondContact O-OG 3.4Å; V264-S369 VanDerWaalsContact O-OG 3.07Å; Q365-S369 WeakPolarHBondContact O-CB 3.06Å; Q365-S369 PolarHBondContact O-N 2.9Å; Q365-S369 PolarHBondContact O-OG 3.26Å; A366-S369 PolarHBondContact O-N 3.12Å; A366-S369 PolarHBondContact O-OG 2.93Å; A366-S369 VanDerWaalsContact O-OG 3.1Å; L367-S369 VanDerWaalsContact C-N 3.33Å; L367-S369 PolarHBondContact O-N 3.14Å; S369-E371 VanDerWaalsContact C-N 3.29Å; S369-M473 WeakPolarHBondContact O-CG 3.31Å
370A97.9Very high97.8Very high20 Ų2054.2 Ų54.217%0.16528%0.279CS..Hα-helixtrans-75.7-15.3170.100000113.9I242 R262 A366 L367 M372I242-A370 HydrophobicContact CD1-CB 3.99Å; R262-A370 HydrophobicContact CB-CB 4.04Å; R262-A370 WeakPolarHBondContact O-CA 3.35Å; A366-A370 WeakPolarHBondContact O-CB 3.28Å; A366-A370 PolarHBondContact O-N 2.82Å; L367-A370 PolarHBondContact O-N 3.44Å; A370-M372 HydrophobicContact CB-CB 3.93Å; A370-M372 HydrophobicContact CB-CG 3.77Å; A370-M372 HydrophobicContact CB-SD 3.84Å; A370-M372 PolarHBondContact O-N 2.82Å
371E97.5Very high97.8Very high187 Ų18753.1 Ų53.187%0.87427%0.272SS*.THydrogen-bonded Turntrans5734.2-165.8-60.1179.4-166.900112.5L367 Q368 S369L367-E371 PolarHBondContact O-N 3.04Å; L367-E371 VanDerWaalsContact O-N 3.11Å; Q368-E371 PolarHBondContact O-N 3.33Å; S369-E371 VanDerWaalsContact C-N 3.29Å
372M97.9Very high97.8Very high29 Ų2952.6 Ų52.614%0.14326%0.264CS..  trans-116.2151.7-173.9-71.5177.967.500113.4N227 I242 R262 L367 A370 E376 I377N227-M372 HydrophobicContact CB-CE 3.9Å; N227-M372 WeakPolarHBondContact ND2-CE 3.47Å; I242-M372 HydrophobicContact CG2-CE 4.45Å; I242-M372 HydrophobicContact CG2-SD 3.98Å; R262-M372 HydrophobicContact CB-SD 4.41Å; L367-M372 PolarHBondContact O-N 2.96Å; L367-M372 VanDerWaalsContact O-N 3.15Å; A370-M372 HydrophobicContact CB-CB 3.93Å; A370-M372 HydrophobicContact CB-CG 3.77Å; A370-M372 HydrophobicContact CB-SD 3.84Å; A370-M372 PolarHBondContact O-N 2.82Å; M372-E376 HydrophobicContact CE-CB 3.6Å; M372-I377 HydrophobicContact CE-CD1 3.92Å
373S97.3Very high97.7Very high52 Ų5252.6 Ų52.636%0.36426%0.264SS..  trans-84.5163.216870.60000112.6D375 E376S373-D375 VanDerWaalsContact C-N 3.3Å; S373-D375 PolarHBondContact O-N 3.37Å; S373-E376 WeakPolarHBondContact CB-OE2 3.49Å; S373-E376 PolarHBondContact N-OE2 3.23Å; S373-E376 PolarHBondContact O-N 3.38Å; S373-E376 WeakPolarHBondContact OG-CG 3.42Å; S373-E376 PolarHBondContact OG-OE2 3.12Å
374L97.1Very high97.5Very high47 Ų4752.8 Ų52.825%0.24627%0.267CS..SBendtrans-72.8-22.9179.5-176.759.7000112.8L367 E376 I377 V400 K402L367-L374 HydrophobicContact CD1-CB 4.26Å; L367-L374 HydrophobicContact CD1-CD1 4.21Å; L374-E376 VanDerWaalsContact C-N 3.34Å; L374-I377 PolarHBondContact O-N 3.16Å; L374-V400 HydrophobicContact CD1-CB 4.21Å; L374-V400 WeakPolarHBondContact CD2-O 3.41Å; L374-K402 PolarHBondContact O-NZ 2.92Å
375D96.6Very high97.3Very high145 Ų14548.3 Ų48.378%0.77526%0.255SS*.THydrogen-bonded Turntrans-73.3-27.1177.7-61.7-42.9000112.2S373 I377S373-D375 VanDerWaalsContact C-N 3.3Å; S373-D375 PolarHBondContact O-N 3.37Å; D375-I377 PolarHBondContact O-N 2.93Å
376E97.4Very high97.3Very high92 Ų9245.6 Ų45.643%0.4324%0.243SC..THydrogen-bonded Turntrans-73.8-6.1174.9-68.6165.181.400114N227 M372 S373 L374N227-E376 WeakPolarHBondContact CB-O 3.23Å; N227-E376 PolarHBondContact ND2-O 3.43Å; N227-E376 VanDerWaalsContact ND2-O 3.15Å; M372-E376 HydrophobicContact CE-CB 3.6Å; S373-E376 WeakPolarHBondContact CB-OE2 3.49Å; S373-E376 PolarHBondContact N-OE2 3.23Å; S373-E376 PolarHBondContact O-N 3.38Å; S373-E376 WeakPolarHBondContact OG-CG 3.42Å; S373-E376 PolarHBondContact OG-OE2 3.12Å; L374-E376 VanDerWaalsContact C-N 3.34Å
377I98.3Very high97.2Very high2 Ų245.9 Ų45.91%0.0125%0.245CC..  trans-93115.4178.6-52.9-59.8000109.6N227 M229 I242 L367 M372 L374 D375 V380 K402N227-I377 HydrophobicContact CB-CD1 4.38Å; M229-I377 HydrophobicContact CB-CG2 3.73Å; M229-I377 HydrophobicContact CE-CD1 4.42Å; M229-I377 HydrophobicContact CE-CG1 4.17Å; I242-I377 HydrophobicContact CD1-CD1 4.06Å; I242-I377 HydrophobicContact CG1-CD1 4.17Å; I242-I377 HydrophobicContact CG2-CD1 3.74Å; L367-I377 HydrophobicContact CD2-CD1 4.31Å; L367-I377 HydrophobicContact CD2-CG1 4.04Å; M372-I377 HydrophobicContact CE-CD1 3.92Å; L374-I377 PolarHBondContact O-N 3.16Å; D375-I377 PolarHBondContact O-N 2.93Å; I377-V380 HydrophobicContact CG2-CG2 4.2Å; I377-K402 WeakPolarHBondContact O-CE 3.45Å; I377-K402 PolarHBondContact O-NZ 3.39Å
378E96.4Very high97.1Very high109 Ų10950.1 Ų50.151%0.50926%0.259SS..  trans-73.8-45.3-177.8-59.7179.5156.300111.9Q226 N227 I228Q226-E378 WeakPolarHBondContact CA-OE2 3.44Å; Q226-E378 VanDerWaalsContact CB-OE2 3.24Å; Q226-E378 WeakPolarHBondContact CB-OE2 3.39Å; Q226-E378 WeakPolarHBondContact CG-OE2 3.48Å; N227-E378 PolarHBondContact O-N 3.34Å; I228-E378 HydrophobicContact CD1-CB 4.22Å
379Q96.7Very high97.1Very high42 Ų4243.6 Ų43.620%0.19623%0.229CC..EExtended strand (participates in β ladder)trans-143.7143.4-179.3-167.5173.338.600111.4I228 M229 I381 N408I228-Q379 HydrophobicContact CD1-CB 3.99Å; M229-Q379 PolarHBondContact N-O 3.01Å; Q379-I381 HydrophobicContact CG-CG1 3.93Å; Q379-N408 PolarHBondContact NE2-ND2 3.42Å; Q379-N408 PolarHBondContact OE1-ND2 2.98Å
380V98.4Very high97.1Very high1 Ų145 Ų451%0.00624%0.237CC..EExtended strand (participates in β ladder)trans-106121.3166.8-175.60000108M229 I377 V400 K402 L405 G406M229-V380 HydrophobicContact CB-CG2 4.19Å; M229-V380 HydrophobicContact CG-CG1 4.28Å; M229-V380 HydrophobicContact CG-CG2 4.5Å; M229-V380 CarbonylContact O-C 3.51Å; M229-V380 WeakPolarHBondContact O-CA 3.47Å; M229-V380 HydrophobicContact SD-CG1 4.14Å; M229-V380 HydrophobicContact SD-CG2 3.97Å; I377-V380 HydrophobicContact CG2-CG2 4.2Å; V380-V400 HydrophobicContact CB-CG2 4.45Å; V380-V400 HydrophobicContact CG1-CG1 4.36Å; V380-V400 HydrophobicContact CG2-CB 3.93Å; V380-V400 HydrophobicContact CG2-CG1 4.04Å; V380-V400 HydrophobicContact CG2-CG2 3.97Å; V380-K402 HydrophobicContact CG2-CG 4.35Å; V380-L405 HydrophobicContact CB-CD2 4.04Å; V380-L405 HydrophobicContact CG1-CD2 3.88Å; V380-G406 WeakPolarHBondContact O-CA 3.3Å; V380-G406 PolarHBondContact O-N 3.16Å
381I98.3Very high97.2Very high0 Ų048.4 Ų48.40%025%0.246CC..EExtended strand (participates in β ladder)trans-111.4133.7-175.1-60-179.1000109.8Y213 I228 M229 F230 Y231 Q379 G406 I409Y213-I381 HydrophobicContact CD2-CD1 3.7Å; Y213-I381 HydrophobicContact CE2-CD1 3.26Å; Y213-I381 HydrophobicContact CG-CD1 4.49Å; I228-I381 HydrophobicContact CG2-CD1 3.52Å; I228-I381 HydrophobicContact CG2-CG1 3.94Å; M229-I381 PolarHBondContact O-N 2.74Å; F230-I381 HydrophobicContact CD1-CB 4.08Å; F230-I381 HydrophobicContact CD1-CG2 4.18Å; F230-I381 HydrophobicContact CE1-CB 4.21Å; F230-I381 HydrophobicContact CE1-CD1 3.91Å; F230-I381 HydrophobicContact CE1-CG2 4.21Å; F230-I381 HydrophobicContact CZ-CD1 4.15Å; Y231-I381 PolarHBondContact N-O 3.09Å; Q379-I381 HydrophobicContact CG-CG1 3.93Å; I381-G406 WeakPolarHBondContact CA-O 3.3Å; I381-I409 HydrophobicContact CG2-CG2 3.7Å
382L98.1Very high97.2Very high10 Ų1039.5 Ų39.55%0.05220%0.204CC..EExtended strand (participates in β ladder)trans-86.4134.3-178.9-57.7-179.8000112.3T387 Q393 L396 L405 G406 K407L382-T387 HydrophobicContact CD2-CG2 4.33Å; L382-Q393 HydrophobicContact CD1-CG 3.74Å; L382-L396 HydrophobicContact CD2-CD2 3.55Å; L382-L405 HydrophobicContact CD1-CB 3.86Å; L382-L405 HydrophobicContact CD1-CD1 4.33Å; L382-L405 HydrophobicContact CD2-CB 4.16Å; L382-L405 HydrophobicContact CD2-CD1 4.18Å; L382-L405 HydrophobicContact CD2-CD2 4.3Å; L382-L405 HydrophobicContact CD2-CG 4.44Å; L382-L405 HydrophobicContact CG-CB 3.97Å; L382-G406 PolarHBondContact N-O 3.44Å; L382-K407 HydrophobicContact CD1-CG 4.29Å
383V96.7Very high97.2Very high2 Ų240.2 Ų40.21%0.01221%0.207CC..EExtended strand (participates in β ladder)trans-133.4162.8176.9-163.50000108.1T209 F230 Y231 D232 M233 T387T209-V383 HydrophobicContact CG2-CG1 4.06Å; T209-V383 HydrophobicContact CG2-CG2 3.78Å; F230-V383 HydrophobicContact CB-CG2 4.38Å; F230-V383 HydrophobicContact CD1-CG2 4.18Å; Y231-V383 PolarHBondContact O-N 3.35Å; D232-V383 WeakPolarHBondContact CA-O 3.48Å; D232-V383 HydrophobicContact CB-CB 3.83Å; D232-V383 HydrophobicContact CB-CG1 4.21Å; D232-V383 VanDerWaalsContact OD2-CG1 3.32Å; D232-V383 WeakPolarHBondContact OD2-CG1 3.2Å; M233-V383 PolarHBondContact N-O 2.97Å; V383-T387 WeakPolarHBondContact O-CG2 3.5Å; V383-T387 PolarHBondContact O-OG1 3.12Å
384G94.8Very high97.3Very high8 Ų842.4 Ų42.48%0.08221%0.212CC..SBendtrans79.5154174.100000115.2D232 M233 A386 T387D232-G384 WeakPolarHBondContact OD1-CA 3.43Å; M233-G384 CarbonylContact O-C 3.48Å; M233-G384 VanDerWaalsContact O-C 3.26Å; G384-A386 PolarHBondContact O-N 3.03Å; G384-T387 PolarHBondContact O-OG1 2.92Å
385G94.1Very high97.4Very high36 Ų3641.5 Ų41.537%0.37121%0.208SC..SBendtrans-71.7-29.2-16900000115.7M233 R388M233-G385 PolarHBondContact O-N 3.14Å; G385-R388 WeakPolarHBondContact O-CB 3.34Å
386A97.2Very high97.4Very high2 Ų234.6 Ų34.62%0.01717%0.171CC..G310 helixtrans-90.3-12-173.700000113.8M233 G234 G384 R388 V389M233-A386 HydrophobicContact CB-CB 4.5Å; M233-A386 HydrophobicContact CE-CB 4.34Å; M233-A386 HydrophobicContact CG-CB 3.95Å; M233-A386 WeakPolarHBondContact O-CB 3.27Å; M233-A386 PolarHBondContact O-N 3.29Å; M233-A386 HydrophobicContact SD-CB 4.34Å; G234-A386 WeakPolarHBondContact O-CB 3.39Å; G384-A386 PolarHBondContact O-N 3.03Å; A386-R388 PolarHBondContact O-N 3.08Å; A386-R388 VanDerWaalsContact O-N 3.12Å; A386-V389 WeakPolarHBondContact O-CB 3.39Å; A386-V389 PolarHBondContact O-N 3.25Å; A386-V389 VanDerWaalsContact O-N 3.11Å
387T97.4Very high97.5Very high6 Ų633.1 Ų33.14%0.03717%0.166CC..G310 helixtrans-60.1-18.2165.6580000112.6Y231 M233 L382 V383 G384 V389 Q393Y231-T387 HydrophobicContact CD1-CG2 3.98Å; Y231-T387 HydrophobicContact CE1-CG2 4.25Å; M233-T387 HydrophobicContact CB-CG2 3.65Å; L382-T387 HydrophobicContact CD2-CG2 4.33Å; V383-T387 WeakPolarHBondContact O-CG2 3.5Å; V383-T387 PolarHBondContact O-OG1 3.12Å; G384-T387 PolarHBondContact O-OG1 2.92Å; T387-V389 PolarHBondContact O-N 3.22Å; T387-Q393 WeakPolarHBondContact O-CG 3.03Å; T387-Q393 PolarHBondContact O-NE2 3.27Å
388R96.4Very high97.5Very high114 Ų11441.6 Ų41.643%0.4320%0.203SC..G310 helixtrans-67.7-15.2174.9-62.8-174.9173.21032.1114.1G385 A386 D412G385-R388 WeakPolarHBondContact O-CB 3.34Å; A386-R388 PolarHBondContact O-N 3.08Å; A386-R388 VanDerWaalsContact O-N 3.12Å; R388-D412 IonicContact CZ-OD1 2.83Å; R388-D412 IonicContact NH1-OD1 2.75Å; R388-D412 PolarHBondContact NH1-OD1 3.24Å; R388-D412 IonicContact NH1-OD2 3.55Å; R388-D412 IonicContact NH2-OD1 2.69Å; R388-D412 PolarHBondContact NH2-OD1 3.45Å; R388-D412 IonicContact NH2-OD2 2.74Å
389V98.1Very high97.5Very high1 Ų138 Ų381%0.00619%0.192CC..SBendtrans-69.5123.5173.8174.60000109.6M275 K317 F348 F356 A386 T387 R391 V392 Q393M275-V389 HydrophobicContact SD-CG2 4.13Å; K317-V389 HydrophobicContact CG-CG2 4.45Å; F348-V389 HydrophobicContact CE1-CG1 3.97Å; F348-V389 HydrophobicContact CE1-CG2 4.35Å; F348-V389 HydrophobicContact CZ-CG2 4.48Å; F356-V389 HydrophobicContact CE1-CG1 4.2Å; F356-V389 HydrophobicContact CZ-CG1 4.27Å; A386-V389 WeakPolarHBondContact O-CB 3.39Å; A386-V389 PolarHBondContact O-N 3.25Å; A386-V389 VanDerWaalsContact O-N 3.11Å; T387-V389 PolarHBondContact O-N 3.22Å; V389-R391 HydrophobicContact CG1-CB 4.48Å; V389-R391 PolarHBondContact O-N 3.07Å; V389-V392 HydrophobicContact CB-CB 4.43Å; V389-V392 HydrophobicContact CB-CG2 3.9Å; V389-V392 HydrophobicContact CG1-CG2 4.15Å; V389-V392 WeakPolarHBondContact O-CB 3.32Å; V389-V392 PolarHBondContact O-N 2.85Å; V389-Q393 PolarHBondContact O-N 3.48Å
390P97.8Very high97.6Very high40 Ų4036 Ų3626%0.2618%0.182SC..Hα-helixtrans-53.7-45.3-174.5-30.636.7000114.3S321 V392 Q393 E394S321-P390 WeakPolarHBondContact O-CG 3.43Å; P390-V392 VanDerWaalsContact C-N 3.27Å; P390-V392 PolarHBondContact O-N 2.94Å; P390-Q393 WeakPolarHBondContact O-CB 3.49Å; P390-Q393 PolarHBondContact O-N 2.95Å; P390-Q393 VanDerWaalsContact O-N 3.09Å; P390-E394 PolarHBondContact O-N 2.97Å
391R98.3Very high97.4Very high91 Ų9139 Ų3934%0.34321%0.214SC..Hα-helixtrans-61.8-29.2178.8-168.960.9174.5175.22.8114.3E349 F356 V389 E394 V395E349-R391 HydrophobicContact CG-CB 3.9Å; E349-R391 HydrophobicContact CG-CG 4.31Å; F356-R391 HydrophobicContact CB-CG 4.42Å; F356-R391 HydrophobicContact CD1-CB 4.33Å; F356-R391 HydrophobicContact CD1-CG 4.02Å; F356-R391 HydrophobicContact CD2-CB 4.31Å; F356-R391 HydrophobicContact CD2-CG 3.44Å; F356-R391 VanDerWaalsContact CD2-CG 3.44Å; F356-R391 HydrophobicContact CE1-CB 4.01Å; F356-R391 HydrophobicContact CE1-CG 4.11Å; F356-R391 HydrophobicContact CE2-CB 3.98Å; F356-R391 HydrophobicContact CE2-CG 3.53Å; F356-R391 HydrophobicContact CG-CB 4.49Å; F356-R391 HydrophobicContact CG-CG 3.71Å; F356-R391 HydrophobicContact CZ-CB 3.82Å; F356-R391 HydrophobicContact CZ-CG 3.88Å; V389-R391 HydrophobicContact CG1-CB 4.48Å; V389-R391 PolarHBondContact O-N 3.07Å; R391-E394 WeakPolarHBondContact CD-OE2 3.49Å; R391-E394 IonicContact CZ-OE1 3.48Å; R391-E394 IonicContact CZ-OE2 2.81Å; R391-E394 IonicContact NE-OE2 2.75Å; R391-E394 IonicContact NH1-OE1 3.67Å; R391-E394 PolarHBondContact NH1-OE1 3.5Å; R391-E394 IonicContact NH1-OE2 2.66Å; R391-E394 PolarHBondContact NH1-OE2 3.1Å; R391-V395 WeakPolarHBondContact O-CG2 3.43Å; R391-V395 PolarHBondContact O-N 3.1Å; R391-V395 VanDerWaalsContact O-N 3.1Å
392V98.4Very high97.3Very high0 Ų041.5 Ų41.50%023%0.225CC..Hα-helixtrans-67.6-45.8173177.80000110.1M233 M275 F356 V359 V389 P390 L396M233-V392 HydrophobicContact CE-CG2 4.47Å; M233-V392 HydrophobicContact SD-CB 4.48Å; M233-V392 HydrophobicContact SD-CG1 3.66Å; M233-V392 HydrophobicContact SD-CG2 3.92Å; M275-V392 HydrophobicContact CE-CG2 3.95Å; F356-V392 HydrophobicContact CD1-CG2 3.95Å; F356-V392 HydrophobicContact CE1-CG2 3.71Å; V359-V392 HydrophobicContact CG1-CG1 4.45Å; V359-V392 HydrophobicContact CG2-CG1 4.21Å; V389-V392 HydrophobicContact CB-CB 4.43Å; V389-V392 HydrophobicContact CB-CG2 3.9Å; V389-V392 HydrophobicContact CG1-CG2 4.15Å; V389-V392 WeakPolarHBondContact O-CB 3.32Å; V389-V392 PolarHBondContact O-N 2.85Å; P390-V392 VanDerWaalsContact C-N 3.27Å; P390-V392 PolarHBondContact O-N 2.94Å; V392-L396 WeakPolarHBondContact O-CB 3.45Å; V392-L396 PolarHBondContact O-N 2.69Å
393Q98.3Very high97.1Very high44 Ų4450.4 Ų50.421%0.20627%0.266CS..Hα-helixtrans-63.8-41.7176-84.3169.473.900112.3L382 T387 V389 P390 L397 L405L382-Q393 HydrophobicContact CD1-CG 3.74Å; T387-Q393 WeakPolarHBondContact O-CG 3.03Å; T387-Q393 PolarHBondContact O-NE2 3.27Å; V389-Q393 PolarHBondContact O-N 3.48Å; P390-Q393 WeakPolarHBondContact O-CB 3.49Å; P390-Q393 PolarHBondContact O-N 2.95Å; P390-Q393 VanDerWaalsContact O-N 3.09Å; Q393-L397 WeakPolarHBondContact O-CB 3.41Å; Q393-L397 PolarHBondContact O-N 2.62Å; Q393-L405 HydrophobicContact CB-CD1 4.09Å; Q393-L405 HydrophobicContact CG-CD1 4.05Å; Q393-L405 WeakPolarHBondContact O-CD1 3.4Å
394E98.4Very high97.1Very high99 Ų9956.8 Ų56.846%0.46330%0.296SS..Hα-helixtrans-60.8-51.5177.7-171.3-153.4143.900111.9P390 R391 L396 L397 K398P390-E394 PolarHBondContact O-N 2.97Å; R391-E394 WeakPolarHBondContact CD-OE2 3.49Å; R391-E394 IonicContact CZ-OE1 3.48Å; R391-E394 IonicContact CZ-OE2 2.81Å; R391-E394 IonicContact NE-OE2 2.75Å; R391-E394 IonicContact NH1-OE1 3.67Å; R391-E394 PolarHBondContact NH1-OE1 3.5Å; R391-E394 IonicContact NH1-OE2 2.66Å; R391-E394 PolarHBondContact NH1-OE2 3.1Å; E394-L396 PolarHBondContact O-N 3.15Å; E394-L397 PolarHBondContact O-N 2.9Å; E394-K398 WeakPolarHBondContact O-CB 3.34Å; E394-K398 PolarHBondContact O-N 3.26Å
395V98.6Very high97.2Very high27 Ų2757 Ų5716%0.16430%0.295CS..Hα-helixtrans-67-38.3-179.3174.60000111.2F356 V359 P360 R391 A399F356-V395 HydrophobicContact CB-CG2 4.38Å; V359-V395 HydrophobicContact CB-CG1 4.07Å; V359-V395 HydrophobicContact CG1-CB 4.35Å; V359-V395 HydrophobicContact CG1-CG1 4.07Å; P360-V395 HydrophobicContact CG-CG1 4.04Å; R391-V395 WeakPolarHBondContact O-CG2 3.43Å; R391-V395 PolarHBondContact O-N 3.1Å; R391-V395 VanDerWaalsContact O-N 3.1Å; V395-A399 VanDerWaalsContact O-CB 3.3Å; V395-A399 WeakPolarHBondContact O-CB 3.47Å; V395-A399 PolarHBondContact O-N 2.69Å
396L98.5Very high97.3Very high1 Ų155.4 Ų55.41%0.00528%0.278CS..Hα-helixtrans-66.8-47.2176.2-177.462.5000111.9Y231 V359 V363 L382 V392 E394 K398 A399 V400 L405Y231-L396 HydrophobicContact CD1-CD1 4.41Å; Y231-L396 HydrophobicContact CD1-CD2 3.48Å; Y231-L396 VanDerWaalsContact CD1-CD2 3.48Å; Y231-L396 HydrophobicContact CD2-CD1 3.71Å; Y231-L396 HydrophobicContact CD2-CD2 4.19Å; Y231-L396 HydrophobicContact CE1-CD1 4.41Å; Y231-L396 HydrophobicContact CE1-CD2 3.83Å; Y231-L396 HydrophobicContact CE2-CD1 3.71Å; Y231-L396 HydrophobicContact CE2-CD2 4.49Å; Y231-L396 HydrophobicContact CG-CD1 4.08Å; Y231-L396 HydrophobicContact CG-CD2 3.68Å; V359-L396 HydrophobicContact CG1-CB 3.88Å; V359-L396 HydrophobicContact CG1-CD1 4.39Å; V363-L396 HydrophobicContact CG2-CD1 3.69Å; L382-L396 HydrophobicContact CD2-CD2 3.55Å; V392-L396 WeakPolarHBondContact O-CB 3.45Å; V392-L396 PolarHBondContact O-N 2.69Å; E394-L396 PolarHBondContact O-N 3.15Å; L396-K398 VanDerWaalsContact C-N 3.29Å; L396-K398 PolarHBondContact O-N 3.36Å; L396-A399 CarbonylContact O-C 3.58Å; L396-A399 WeakPolarHBondContact O-CA 3.23Å; L396-A399 WeakPolarHBondContact O-CB 3.44Å; L396-A399 PolarHBondContact O-N 2.94Å; L396-V400 HydrophobicContact CD1-CG1 3.93Å; L396-V400 HydrophobicContact CG-CG1 4.43Å; L396-V400 WeakPolarHBondContact O-CG1 3.41Å; L396-V400 WeakPolarHBondContact O-CG2 3.5Å; L396-V400 PolarHBondContact O-N 3.09Å; L396-L405 HydrophobicContact CB-CD1 4.32Å; L396-L405 HydrophobicContact CD2-CD1 4.23Å; L396-L405 HydrophobicContact CD2-CD2 4.1Å; L396-L405 HydrophobicContact CG-CD1 4.33Å; L396-L405 HydrophobicContact CG-CD2 4.07Å
397L98.3Very high97.1Very high60 Ų6062.1 Ų62.131%0.31431%0.307SS..Hα-helixtrans-55.8-47.2177.4-176.372.9000110.4Q393 E394 A399 V400 G401 K402 L405Q393-L397 WeakPolarHBondContact O-CB 3.41Å; Q393-L397 PolarHBondContact O-N 2.62Å; E394-L397 PolarHBondContact O-N 2.9Å; L397-A399 VanDerWaalsContact C-N 3.32Å; L397-A399 PolarHBondContact O-N 2.91Å; L397-V400 PolarHBondContact O-N 2.93Å; L397-G401 PolarHBondContact O-N 2.83Å; L397-K402 VanDerWaalsContact CD1-O 3.22Å; L397-K402 WeakPolarHBondContact CD1-O 3.29Å; L397-L405 HydrophobicContact CB-CD1 3.93Å; L397-L405 HydrophobicContact CB-CG 4.26Å; L397-L405 HydrophobicContact CD1-CD1 4.43Å; L397-L405 HydrophobicContact CD1-CG 3.9Å
398K98.1Very high96.7Very high180 Ų18064.4 Ų64.478%0.78332%0.319SS*.Hα-helixtrans-61.9-35.8175-175.5176.9-179.9178.40113.1E394 L396E394-K398 WeakPolarHBondContact O-CB 3.34Å; E394-K398 PolarHBondContact O-N 3.26Å; L396-K398 VanDerWaalsContact C-N 3.29Å; L396-K398 PolarHBondContact O-N 3.36Å
399A97.6Very high96.5Very high34 Ų3460.6 Ų60.628%0.28131%0.307SS..Hα-helixtrans-75.5-28.5178.300000113.7P360 V395 L396 L397P360-A399 HydrophobicContact CB-CB 3.88Å; P360-A399 HydrophobicContact CG-CB 3.96Å; V395-A399 VanDerWaalsContact O-CB 3.3Å; V395-A399 WeakPolarHBondContact O-CB 3.47Å; V395-A399 PolarHBondContact O-N 2.69Å; L396-A399 CarbonylContact O-C 3.58Å; L396-A399 WeakPolarHBondContact O-CA 3.23Å; L396-A399 WeakPolarHBondContact O-CB 3.44Å; L396-A399 PolarHBondContact O-N 2.94Å; L397-A399 VanDerWaalsContact C-N 3.32Å; L397-A399 PolarHBondContact O-N 2.91Å
400V97.6Very high96.3Very high0 Ų064.1 Ų64.10%033%0.326CS..Hα-helixtrans-97.4-9.5179.9-53.20000114.6M229 V363 L374 V380 L396 L397 K402 L405M229-V400 HydrophobicContact SD-CG1 4.5Å; V363-V400 HydrophobicContact CG1-CG1 4.16Å; V363-V400 HydrophobicContact CG2-CG1 4.31Å; L374-V400 HydrophobicContact CD1-CB 4.21Å; L374-V400 WeakPolarHBondContact CD2-O 3.41Å; V380-V400 HydrophobicContact CB-CG2 4.45Å; V380-V400 HydrophobicContact CG1-CG1 4.36Å; V380-V400 HydrophobicContact CG2-CB 3.93Å; V380-V400 HydrophobicContact CG2-CG1 4.04Å; V380-V400 HydrophobicContact CG2-CG2 3.97Å; L396-V400 HydrophobicContact CD1-CG1 3.93Å; L396-V400 HydrophobicContact CG-CG1 4.43Å; L396-V400 WeakPolarHBondContact O-CG1 3.41Å; L396-V400 WeakPolarHBondContact O-CG2 3.5Å; L396-V400 PolarHBondContact O-N 3.09Å; L397-V400 PolarHBondContact O-N 2.93Å; V400-K402 HydrophobicContact CB-CG 4.41Å; V400-K402 HydrophobicContact CG2-CB 4.23Å; V400-K402 HydrophobicContact CG2-CG 3.96Å; V400-K402 WeakPolarHBondContact O-CE 3.18Å; V400-K402 WeakPolarHBondContact O-CG 3.41Å; V400-K402 PolarHBondContact O-N 3.16Å; V400-K402 VanDerWaalsContact O-N 3.1Å; V400-L405 HydrophobicContact CG2-CD2 3.92Å
401G95.6Very high95.9Very high65 Ų6563.1 Ų63.167%0.6732%0.321SS*.THydrogen-bonded Turntrans62.219.8171.900000115.2L397L397-G401 PolarHBondContact O-N 2.83Å
402K94.3Very high95.7Very high51 Ų5159.8 Ų59.822%0.22231%0.31CS..  trans-94.7160.6176.9-52.2-59.1167.3172.10110.1L374 I377 V380 L397 V400L374-K402 PolarHBondContact O-NZ 2.92Å; I377-K402 WeakPolarHBondContact O-CE 3.45Å; I377-K402 PolarHBondContact O-NZ 3.39Å; V380-K402 HydrophobicContact CG2-CG 4.35Å; L397-K402 VanDerWaalsContact CD1-O 3.22Å; L397-K402 WeakPolarHBondContact CD1-O 3.29Å; V400-K402 HydrophobicContact CB-CG 4.41Å; V400-K402 HydrophobicContact CG2-CB 4.23Å; V400-K402 HydrophobicContact CG2-CG 3.96Å; V400-K402 WeakPolarHBondContact O-CE 3.18Å; V400-K402 WeakPolarHBondContact O-CG 3.41Å; V400-K402 PolarHBondContact O-N 3.16Å; V400-K402 VanDerWaalsContact O-N 3.1Å
403E94.5Very high95.5Very high198 Ų19861.1 Ų61.193%0.92532%0.316SS*.SBendtrans-69.2-35177.4-60.9-176.6161.500112.3
404E96.4Very high95.5Very high136 Ų13659.2 Ų59.264%0.63631%0.308SS*.  trans-142.5166.4177.462.5160.1-151.200113.5
405L97.6Very high95.5Very high12 Ų1254.9 Ų54.96%0.06329%0.289CS..  trans-109122.9171.7-68.2165.9000109.4V380 L382 Q393 L396 L397 V400 K407V380-L405 HydrophobicContact CB-CD2 4.04Å; V380-L405 HydrophobicContact CG1-CD2 3.88Å; L382-L405 HydrophobicContact CD1-CB 3.86Å; L382-L405 HydrophobicContact CD1-CD1 4.33Å; L382-L405 HydrophobicContact CD2-CB 4.16Å; L382-L405 HydrophobicContact CD2-CD1 4.18Å; L382-L405 HydrophobicContact CD2-CD2 4.3Å; L382-L405 HydrophobicContact CD2-CG 4.44Å; L382-L405 HydrophobicContact CG-CB 3.97Å; Q393-L405 HydrophobicContact CB-CD1 4.09Å; Q393-L405 HydrophobicContact CG-CD1 4.05Å; Q393-L405 WeakPolarHBondContact O-CD1 3.4Å; L396-L405 HydrophobicContact CB-CD1 4.32Å; L396-L405 HydrophobicContact CD2-CD1 4.23Å; L396-L405 HydrophobicContact CD2-CD2 4.1Å; L396-L405 HydrophobicContact CG-CD1 4.33Å; L396-L405 HydrophobicContact CG-CD2 4.07Å; L397-L405 HydrophobicContact CB-CD1 3.93Å; L397-L405 HydrophobicContact CB-CG 4.26Å; L397-L405 HydrophobicContact CD1-CD1 4.43Å; L397-L405 HydrophobicContact CD1-CG 3.9Å; V400-L405 HydrophobicContact CG2-CD2 3.92Å; L405-K407 PolarHBondContact O-N 3.12Å
406G95.4Very high95.4Very high2 Ų253.6 Ų53.62%0.02128%0.281CS..BIsolated β-bridgetrans-63.5126.1-173.900000113.3V380 I381 L382V380-G406 WeakPolarHBondContact O-CA 3.3Å; V380-G406 PolarHBondContact O-N 3.16Å; I381-G406 WeakPolarHBondContact CA-O 3.3Å; L382-G406 PolarHBondContact N-O 3.44Å
407K94.3Very high95.4Very high143 Ų14355.1 Ų55.162%0.62229%0.289SS*.  trans-118.922.9178.1-67159.5-173.2173.30111.6L382 L405 I409L382-K407 HydrophobicContact CD1-CG 4.29Å; L405-K407 PolarHBondContact O-N 3.12Å; K407-I409 PolarHBondContact O-N 2.99Å; K407-I409 VanDerWaalsContact O-N 3.16Å
408N89.1Confident95.4Very high54 Ų5452.2 Ų52.229%0.28927%0.274SS..  trans-83.226.2-172.456.6-9.9000114.1R217 Q379R217-N408 PolarHBondContact NH1-ND2 2.8Å; R217-N408 PolarHBondContact NH2-ND2 2.81Å; Q379-N408 PolarHBondContact NE2-ND2 3.42Å; Q379-N408 PolarHBondContact OE1-ND2 2.98Å
409I92.4Very high95.4Very high34 Ų3443.7 Ų43.717%0.17424%0.236CC..SBendtrans-150.6149.5178.9-161170.9000110.4T209 I381 K407 A411 A414T209-I409 HydrophobicContact CG2-CD1 4.1Å; I381-I409 HydrophobicContact CG2-CG2 3.7Å; K407-I409 PolarHBondContact O-N 2.99Å; K407-I409 VanDerWaalsContact O-N 3.16Å; I409-A411 VanDerWaalsContact C-N 3.34Å; I409-A411 PolarHBondContact O-N 3.31Å; I409-A414 HydrophobicContact CD1-CB 3.56Å; I409-A414 HydrophobicContact CG1-CB 3.88Å
410N93.8Very high95.5Very high76 Ų7642 Ų4241%0.40622%0.223SC..  trans-7489.9169.3-174.5-10.9000109.8D412 E413 A414N410-D412 PolarHBondContact O-N 3.1Å; N410-D412 PolarHBondContact OD1-N 2.9Å; N410-D412 VanDerWaalsContact OD1-N 3.17Å; N410-E413 HydrophobicContact CB-CB 4.41Å; N410-E413 WeakPolarHBondContact ND2-CG 3.48Å; N410-E413 PolarHBondContact ND2-OE1 2.9Å; N410-E413 VanDerWaalsContact ND2-OE1 3.08Å; N410-E413 PolarHBondContact ND2-OE2 3.42Å; N410-E413 PolarHBondContact O-N 3.16Å; N410-A414 WeakPolarHBondContact O-CB 3.43Å; N410-A414 PolarHBondContact O-N 2.79Å
411A89.3Confident95.5Very high19 Ų1943 Ų4316%0.15723%0.227CC..THydrogen-bonded Turntrans-55.1-17.8-179.800000115.2I409I409-A411 VanDerWaalsContact C-N 3.34Å; I409-A411 PolarHBondContact O-N 3.31Å
412D92.4Very high95.6Very high21 Ų2140.9 Ų40.911%0.11220%0.199CC..THydrogen-bonded Turntrans-89.5-23.7176.8-78.617.1000113K46 K67 R388 N410K46-D412 WeakPolarHBondContact CD-O 3.49Å; K46-D412 WeakPolarHBondContact CE-O 3.49Å; K46-D412 PolarHBondContact NZ-O 2.76Å; K67-D412 HydrophobicContact CD-CB 4.24Å; K67-D412 WeakPolarHBondContact CD-OD2 3.44Å; K67-D412 WeakPolarHBondContact CE-OD2 3.47Å; K67-D412 IonicContact NZ-OD2 2.71Å; K67-D412 PolarHBondContact NZ-OD2 2.94Å; R388-D412 IonicContact CZ-OD1 2.83Å; R388-D412 IonicContact NH1-OD1 2.75Å; R388-D412 PolarHBondContact NH1-OD1 3.24Å; R388-D412 IonicContact NH1-OD2 3.55Å; R388-D412 IonicContact NH2-OD1 2.69Å; R388-D412 PolarHBondContact NH2-OD1 3.45Å; R388-D412 IonicContact NH2-OD2 2.74Å; N410-D412 PolarHBondContact O-N 3.1Å; N410-D412 PolarHBondContact OD1-N 2.9Å; N410-D412 VanDerWaalsContact OD1-N 3.17Å
413E96Very high95.7Very high28 Ų2838.4 Ų38.413%0.13119%0.189CC..THydrogen-bonded Turntrans-118.4-15.4-170.7-66.9174.8-151.200113.7I58 R66 N410 A415 A416 M417I58-E413 HydrophobicContact CD1-CB 4.23Å; I58-E413 HydrophobicContact CD1-CG 4.35Å; I58-E413 HydrophobicContact CG1-CB 4.26Å; I58-E413 HydrophobicContact CG1-CG 3.98Å; I58-E413 WeakPolarHBondContact CG1-OE2 3.43Å; R66-E413 IonicContact CZ-OE1 3.94Å; R66-E413 IonicContact CZ-OE2 2.79Å; R66-E413 IonicContact NE-OE1 2.7Å; R66-E413 PolarHBondContact NE-OE1 3.18Å; R66-E413 IonicContact NE-OE2 3.96Å; R66-E413 PolarHBondContact NE-OE2 2.67Å; R66-E413 IonicContact NH2-OE1 2.78Å; R66-E413 IonicContact NH2-OE2 3.47Å; R66-E413 PolarHBondContact NH2-OE2 2.88Å; N410-E413 HydrophobicContact CB-CB 4.41Å; N410-E413 WeakPolarHBondContact ND2-CG 3.48Å; N410-E413 PolarHBondContact ND2-OE1 2.9Å; N410-E413 VanDerWaalsContact ND2-OE1 3.08Å; N410-E413 PolarHBondContact ND2-OE2 3.42Å; N410-E413 PolarHBondContact O-N 3.16Å; E413-A415 VanDerWaalsContact C-N 3.35Å; E413-A415 PolarHBondContact O-N 2.96Å; E413-A416 PolarHBondContact O-N 3.31Å; E413-M417 HydrophobicContact CB-CG 4.48Å; E413-M417 WeakPolarHBondContact O-CG 3.47Å; E413-M417 PolarHBondContact O-N 3.11Å
414A96.8Very high95.8Very high3 Ų329 Ų293%0.02515%0.145CC..Hα-helixtrans-54.6-45.1-171.900000113.9T209 S212 I409 N410 M417 G418T209-A414 HydrophobicContact CG2-CB 3.78Å; S212-A414 WeakPolarHBondContact CB-O 3.41Å; S212-A414 PolarHBondContact OG-O 3.31Å; I409-A414 HydrophobicContact CD1-CB 3.56Å; I409-A414 HydrophobicContact CG1-CB 3.88Å; N410-A414 WeakPolarHBondContact O-CB 3.43Å; N410-A414 PolarHBondContact O-N 2.79Å; A414-M417 PolarHBondContact O-N 3.12Å; A414-G418 PolarHBondContact O-N 2.83Å
415A98Very high95.7Very high9 Ų925 Ų257%0.07414%0.135CC..Hα-helixtrans-61.7-46.4179.400000111.9D39 T175 A208 T209 E413 G418 A419D39-A415 HydrophobicContact CB-CB 4.34Å; T175-A415 HydrophobicContact CG2-CB 4.28Å; A208-A415 HydrophobicContact CB-CB 4.41Å; A208-A415 WeakPolarHBondContact CB-O 3.45Å; T209-A415 PolarHBondContact OG1-N 2.73Å; E413-A415 VanDerWaalsContact C-N 3.35Å; E413-A415 PolarHBondContact O-N 2.96Å; A415-G418 PolarHBondContact O-N 2.89Å; A415-A419 WeakPolarHBondContact O-CB 3.35Å; A415-A419 PolarHBondContact O-N 3.47Å
416A98.4Very high95.6Very high0 Ų027.4 Ų27.40%015%0.147CC..Hα-helixtrans-64.7-42.4176.800000111.9S37 D39 K46 A48 I58 E413 G418 A419 V420S37-A416 PolarHBondContact OG-O 3.02Å; D39-A416 HydrophobicContact CB-CB 3.91Å; K46-A416 HydrophobicContact CB-CB 4.27Å; A48-A416 HydrophobicContact CB-CB 3.94Å; I58-A416 HydrophobicContact CD1-CB 3.89Å; E413-A416 PolarHBondContact O-N 3.31Å; A416-G418 PolarHBondContact O-N 2.94Å; A416-A419 PolarHBondContact O-N 2.93Å; A416-V420 PolarHBondContact O-N 2.81Å
417M98Very high95.4Very high32 Ų3227.9 Ų27.916%0.15815%0.151CC..Hα-helixtrans-65.8-37.5178.8-69.2-56-6200112.9M56 I58 E413 A414 V420 Y421M56-M417 HydrophobicContact CB-CE 3.83Å; I58-M417 HydrophobicContact CD1-CG 3.96Å; I58-M417 HydrophobicContact CD1-SD 3.59Å; I58-M417 VanDerWaalsContact CD1-SD 3.59Å; I58-M417 HydrophobicContact CG1-SD 4.06Å; E413-M417 HydrophobicContact CB-CG 4.48Å; E413-M417 WeakPolarHBondContact O-CG 3.47Å; E413-M417 PolarHBondContact O-N 3.11Å; A414-M417 PolarHBondContact O-N 3.12Å; M417-V420 WeakPolarHBondContact O-CG1 3.41Å; M417-Y421 PolarHBondContact O-N 2.85Å
418G98.1Very high95.1Very high0 Ų031.4 Ų31.40%017%0.166CC..Hα-helixtrans-70.8-39.9172.200000112.8A208 L211 A414 A415 A416 Y421 Q422A208-G418 WeakPolarHBondContact O-CA 3.46Å; L211-G418 WeakPolarHBondContact CD2-O 3.45Å; A414-G418 PolarHBondContact O-N 2.83Å; A415-G418 PolarHBondContact O-N 2.89Å; A416-G418 PolarHBondContact O-N 2.94Å; G418-Y421 WeakPolarHBondContact O-CB 3.27Å; G418-Y421 PolarHBondContact O-N 3.01Å; G418-Q422 PolarHBondContact O-N 2.86Å
419A98.6Very high95Very high0 Ų030.8 Ų30.80%017%0.168CC..Hα-helixtrans-65.1-38.9178.400000112.4V173 T175 I203 A208 A415 A416 Q422 A423V173-A419 HydrophobicContact CG1-CB 3.96Å; T175-A419 HydrophobicContact CG2-CB 4.13Å; I203-A419 HydrophobicContact CG2-CB 4.05Å; A208-A419 HydrophobicContact CB-CB 4.37Å; A415-A419 WeakPolarHBondContact O-CB 3.35Å; A415-A419 PolarHBondContact O-N 3.47Å; A416-A419 PolarHBondContact O-N 2.93Å; A419-Q422 PolarHBondContact O-N 2.84Å; A419-A423 PolarHBondContact O-N 3.47Å
420V98.1Very high94.9Very high0 Ų031.3 Ų31.30%017%0.17CC..Hα-helixtrans-72.9-31.7173.873.10000112.6S37 A48 V50 M56 A416 M417 Q422 A423 A424S37-V420 PolarHBondContact OG-N 2.95Å; S37-V420 VanDerWaalsContact OG-N 3.16Å; A48-V420 HydrophobicContact CB-CB 3.9Å; A48-V420 HydrophobicContact CB-CG1 3.79Å; V50-V420 HydrophobicContact CB-CG2 4.24Å; V50-V420 HydrophobicContact CG1-CG2 4.03Å; M56-V420 HydrophobicContact CB-CG1 3.93Å; M56-V420 HydrophobicContact CG-CG1 3.98Å; M56-V420 HydrophobicContact SD-CG1 4.38Å; A416-V420 PolarHBondContact O-N 2.81Å; M417-V420 WeakPolarHBondContact O-CG1 3.41Å; V420-Q422 VanDerWaalsContact C-N 3.28Å; V420-Q422 PolarHBondContact O-N 3.33Å; V420-A423 PolarHBondContact O-N 2.91Å; V420-A424 WeakPolarHBondContact O-CB 3.32Å; V420-A424 PolarHBondContact O-N 2.97Å
421Y97.6Very high94.8Very high20 Ų2037.8 Ų37.88%0.07819%0.194CC..Hα-helixtrans-59.7-42.4169.1-170.3-81.4000111.2M56 L211 V215 R218 M417 G418 A424 A425 V432 K433 F435M56-Y421 HydrophobicContact CE-CD2 3.84Å; M56-Y421 HydrophobicContact CE-CG 4.28Å; M56-Y421 HydrophobicContact SD-CD2 3.81Å; M56-Y421 HydrophobicContact SD-CG 4.37Å; L211-Y421 HydrophobicContact CD1-CD1 4.34Å; L211-Y421 HydrophobicContact CD2-CD1 4.3Å; L211-Y421 HydrophobicContact CG-CD1 4.39Å; V215-Y421 HydrophobicContact CB-CD2 4.38Å; V215-Y421 HydrophobicContact CB-CE2 4.21Å; V215-Y421 HydrophobicContact CG1-CD2 3.67Å; V215-Y421 HydrophobicContact CG1-CE2 3.41Å; V215-Y421 VanDerWaalsContact CG1-CE2 3.41Å; V215-Y421 HydrophobicContact CG1-CG 4.5Å; V215-Y421 HydrophobicContact CG2-CD1 3.85Å; V215-Y421 HydrophobicContact CG2-CD2 3.88Å; V215-Y421 HydrophobicContact CG2-CE1 3.65Å; V215-Y421 HydrophobicContact CG2-CE2 3.65Å; V215-Y421 HydrophobicContact CG2-CG 3.96Å; R218-Y421 PolarHBondContact NH1-OH 3.42Å; R218-Y421 VanDerWaalsContact NH1-OH 3.08Å; R218-Y421 PolarHBondContact NH2-OH 2.95Å; M417-Y421 PolarHBondContact O-N 2.85Å; G418-Y421 WeakPolarHBondContact O-CB 3.27Å; G418-Y421 PolarHBondContact O-N 3.01Å; Y421-A424 PolarHBondContact O-N 3.31Å; Y421-A425 PolarHBondContact O-N 3.35Å; Y421-V432 HydrophobicContact CE1-CB 4.48Å; Y421-V432 HydrophobicContact CE1-CG2 4.13Å; Y421-V432 HydrophobicContact CE2-CB 4.39Å; Y421-K433 PolarHBondContact OH-O 3.49Å; Y421-F435 HydrophobicContact CE1-CB 4.19Å
422Q97.8Very high94.8Very high20 Ų2038.5 Ų38.59%0.09320%0.196CC..Hα-helixtrans-68.7-38.9176-17163.35.200112.2I203 L211 G418 A419 V420 A424 A425 L426I203-Q422 HydrophobicContact CD1-CB 4.33Å; I203-Q422 HydrophobicContact CD1-CG 4.29Å; L211-Q422 HydrophobicContact CD2-CB 3.89Å; G418-Q422 PolarHBondContact O-N 2.86Å; A419-Q422 PolarHBondContact O-N 2.84Å; V420-Q422 VanDerWaalsContact C-N 3.28Å; V420-Q422 PolarHBondContact O-N 3.33Å; Q422-A424 VanDerWaalsContact C-N 3.29Å; Q422-A424 PolarHBondContact O-N 2.87Å; Q422-A425 WeakPolarHBondContact O-CB 3.31Å; Q422-A425 PolarHBondContact O-N 2.63Å; Q422-A425 VanDerWaalsContact O-N 3.08Å; Q422-L426 HydrophobicContact CG-CD1 4.11Å; Q422-L426 WeakPolarHBondContact O-CG 3.34Å; Q422-L426 PolarHBondContact O-N 2.71Å
423A97.2Very high94.8Very high0 Ų044.6 Ų44.60%022%0.222CC..Hα-helixtrans-59-42.1172.700000111.4V35 V173 L200 A419 V420 A425 L426 S427V35-A423 HydrophobicContact CB-CB 4.31Å; V35-A423 HydrophobicContact CG2-CB 3.72Å; V173-A423 HydrophobicContact CB-CB 4.11Å; V173-A423 HydrophobicContact CG2-CB 3.64Å; L200-A423 HydrophobicContact CD1-CB 4.46Å; A419-A423 PolarHBondContact O-N 3.47Å; V420-A423 PolarHBondContact O-N 2.91Å; A423-A425 VanDerWaalsContact C-N 3.32Å; A423-A425 PolarHBondContact O-N 3.19Å; A423-L426 PolarHBondContact O-N 3.17Å; A423-S427 WeakPolarHBondContact O-CB 3.38Å; A423-S427 PolarHBondContact O-N 3.27Å
424A95.9Very high94.6Very high1 Ų146.5 Ų46.51%0.00824%0.237CC..Hα-helixtrans-70.2-24.517500000113.8V50 M56 V420 Y421 Q422 F430 V432V50-A424 HydrophobicContact CG1-CB 3.99Å; M56-A424 HydrophobicContact CE-CB 3.52Å; V420-A424 WeakPolarHBondContact O-CB 3.32Å; V420-A424 PolarHBondContact O-N 2.97Å; Y421-A424 PolarHBondContact O-N 3.31Å; Q422-A424 VanDerWaalsContact C-N 3.29Å; Q422-A424 PolarHBondContact O-N 2.87Å; A424-F430 HydrophobicContact CB-CB 4.28Å; A424-F430 HydrophobicContact CB-CD2 4.37Å; A424-F430 HydrophobicContact CB-CG 4.41Å; A424-V432 HydrophobicContact CB-CG1 3.63Å
425A94.8Very high94.6Very high51 Ų5147.4 Ų47.442%0.42124%0.24SC..Hα-helixtrans-78.3-31.9174.200000112.9Y421 Q422 A423 V432Y421-A425 PolarHBondContact O-N 3.35Å; Q422-A425 WeakPolarHBondContact O-CB 3.31Å; Q422-A425 PolarHBondContact O-N 2.63Å; Q422-A425 VanDerWaalsContact O-N 3.08Å; A423-A425 VanDerWaalsContact C-N 3.32Å; A423-A425 PolarHBondContact O-N 3.19Å; A425-V432 HydrophobicContact CB-CG2 3.74Å
426L94.8Very high94.5Very high62 Ų6248.5 Ų48.533%0.32525%0.246SC..Hα-helixtrans-88.5-25.6178.9-65.6171.9000113V173 L200 Q201 Q422 A423V173-L426 HydrophobicContact CG2-CD1 4.33Å; L200-L426 HydrophobicContact CB-CB 4.3Å; L200-L426 HydrophobicContact CB-CD1 3.95Å; L200-L426 HydrophobicContact CD1-CB 4.12Å; Q201-L426 HydrophobicContact CB-CD1 3.74Å; Q422-L426 HydrophobicContact CG-CD1 4.11Å; Q422-L426 WeakPolarHBondContact O-CG 3.34Å; Q422-L426 PolarHBondContact O-N 2.71Å; A423-L426 PolarHBondContact O-N 3.17Å
427S92Very high94.4Very high13 Ų1349.6 Ų49.69%0.09125%0.253CS..  trans-75.4135.6178.5-179.90000112.6A423 A429A423-S427 WeakPolarHBondContact O-CB 3.38Å; A423-S427 PolarHBondContact O-N 3.27Å; S427-A429 PolarHBondContact O-N 3.14Å; S427-A429 WeakPolarHBondContact OG-CB 3.24Å; S427-A429 PolarHBondContact OG-N 2.92Å
428K87.6Confident94.3Very high217 Ų21752.2 Ų52.294%0.94326%0.261SS*.THydrogen-bonded Turntrans-71.8-12.2173.8-62.9-178.7-178.9178.70113.5F430K428-F430 VanDerWaalsContact C-N 3.34Å
429A87.6Confident94.3Very high41 Ų4152.4 Ų52.434%0.33926%0.262SS..THydrogen-bonded Turntrans-77.5-17.718000000113.5L33 S427L33-A429 HydrophobicContact CB-CB 4.23Å; L33-A429 HydrophobicContact CD2-CB 3.68Å; S427-A429 PolarHBondContact O-N 3.14Å; S427-A429 WeakPolarHBondContact OG-CB 3.24Å; S427-A429 PolarHBondContact OG-N 2.92Å
430F90.7Very high94.3Very high45 Ų4552.5 Ų52.520%0.19726%0.262CS..  trans-125.7162.8-173.4-59.5-76.1000112.6L33 V35 V50 A424 K428L33-F430 WeakPolarHBondContact O-CE2 3.4Å; L33-F430 WeakPolarHBondContact O-CZ 3.37Å; V35-F430 HydrophobicContact CG1-CE2 4.36Å; V35-F430 HydrophobicContact CG2-CD2 4.23Å; V35-F430 HydrophobicContact CG2-CE2 3.86Å; V50-F430 HydrophobicContact CB-CZ 4.36Å; V50-F430 HydrophobicContact CG1-CD2 4.15Å; V50-F430 HydrophobicContact CG1-CE1 4.25Å; V50-F430 HydrophobicContact CG1-CE2 3.71Å; V50-F430 HydrophobicContact CG1-CZ 3.77Å; V50-F430 HydrophobicContact CG2-CD1 4.25Å; V50-F430 HydrophobicContact CG2-CE1 3.79Å; V50-F430 HydrophobicContact CG2-CZ 4.06Å; A424-F430 HydrophobicContact CB-CB 4.28Å; A424-F430 HydrophobicContact CB-CD2 4.37Å; A424-F430 HydrophobicContact CB-CG 4.41Å; K428-F430 VanDerWaalsContact C-N 3.34Å
431K90.3Very high94.3Very high211 Ų21153 Ų5392%0.91727%0.265SS*.  trans-136.281.3174.5-170.2174.3-177.1173.90110.4
432V91.3Very high94.2Very high35 Ų3552.5 Ų52.521%0.21227%0.265CS..PPolyproline II helixtrans-75.2165.9173.2-57.60000111.5M56 Y421 A424 A425M56-V432 HydrophobicContact CE-CG1 3.8Å; Y421-V432 HydrophobicContact CE1-CB 4.48Å; Y421-V432 HydrophobicContact CE1-CG2 4.13Å; Y421-V432 HydrophobicContact CE2-CB 4.39Å; A424-V432 HydrophobicContact CB-CG1 3.63Å; A425-V432 HydrophobicContact CB-CG2 3.74Å
433K91.9Very high94.2Very high148 Ų14852.3 Ų52.364%0.64326%0.263SS*.PPolyproline II helixtrans-71.2128.6173.4-65.9177.8-177.7174.80109R218 Y421 F435R218-K433 VanDerWaalsContact NH2-C 3.34Å; R218-K433 PolarHBondContact NH2-O 3.1Å; Y421-K433 PolarHBondContact OH-O 3.49Å; K433-F435 PolarHBondContact O-N 2.88Å
434P91.9Very high94.2Very high68 Ų6852.7 Ų52.744%0.44227%0.265SS..PPolyproline II helixtrans-56.3129.7-177.1-26.935.1000112.8R218 A253 Q256R218-P434 VanDerWaalsContact NH2-C 3.3Å; R218-P434 PolarHBondContact NH2-O 2.85Å; A253-P434 HydrophobicContact CB-CG 4.35Å; Q256-P434 HydrophobicContact CG-CB 4.24Å; Q256-P434 PolarHBondContact OE1-O 3.19Å; Q256-P434 VanDerWaalsContact OE1-O 3.11Å
435F95.8Very high94.4Very high23 Ų2352.7 Ų52.710%0.10127%0.265CS..  trans-131.8125.1173.1-158.3-71.1000107L211 G214 V215 I221 Y245 P257 L259 Y421 K433 V437L211-F435 HydrophobicContact CD1-CB 4.21Å; L211-F435 HydrophobicContact CD1-CD1 3.64Å; L211-F435 HydrophobicContact CD1-CE1 4.2Å; L211-F435 HydrophobicContact CD1-CG 3.91Å; G214-F435 VanDerWaalsContact C-CE2 3.46Å; G214-F435 WeakPolarHBondContact O-CE2 3.34Å; V215-F435 HydrophobicContact CG2-CD2 3.98Å; V215-F435 HydrophobicContact CG2-CE2 4.48Å; V215-F435 HydrophobicContact CG2-CG 4.38Å; I221-F435 HydrophobicContact CD1-CE2 3.88Å; I221-F435 HydrophobicContact CD1-CZ 3.72Å; Y245-F435 HydrophobicContact CD1-CZ 4.3Å; Y245-F435 HydrophobicContact CE1-CZ 4.47Å; P257-F435 HydrophobicContact CB-CD2 4.03Å; P257-F435 HydrophobicContact CB-CE2 3.65Å; P257-F435 HydrophobicContact CB-CZ 3.99Å; P257-F435 HydrophobicContact CG-CD2 3.54Å; P257-F435 HydrophobicContact CG-CE2 3.67Å; P257-F435 HydrophobicContact CG-CG 4.17Å; P257-F435 HydrophobicContact CG-CZ 4.41Å; L259-F435 HydrophobicContact CB-CE1 3.94Å; L259-F435 HydrophobicContact CD2-CD1 4.41Å; L259-F435 HydrophobicContact CD2-CE1 3.85Å; L259-F435 HydrophobicContact CG-CE1 4.08Å; Y421-F435 HydrophobicContact CE1-CB 4.19Å; K433-F435 PolarHBondContact O-N 2.88Å; F435-V437 PolarHBondContact O-N 2.96Å
436V95.6Very high94.5Very high31 Ų3151.1 Ų51.119%0.18825%0.25CC..EExtended strand (participates in β ladder)trans-88112.9-173.6-176.50000109.3V248 T250 Q256 P257 Q258 L259 R438V248-V436 HydrophobicContact CG2-CG2 4.33Å; T250-V436 HydrophobicContact CG2-CG2 3.76Å; Q256-V436 HydrophobicContact CB-CG2 4.27Å; P257-V436 PolarHBondContact O-N 3.48Å; Q258-V436 CarbonylContact C-O 3.59Å; Q258-V436 VanDerWaalsContact CA-O 3.25Å; Q258-V436 WeakPolarHBondContact CA-O 3.47Å; Q258-V436 HydrophobicContact CB-CB 3.97Å; Q258-V436 HydrophobicContact CB-CG1 4.44Å; Q258-V436 HydrophobicContact CG-CB 4.23Å; Q258-V436 HydrophobicContact CG-CG1 4.22Å; L259-V436 PolarHBondContact N-O 2.88Å; V436-R438 HydrophobicContact CG1-CG 4.4Å
437V96.9Very high94.6Very high24 Ų2448.1 Ų48.115%0.14523%0.234CC..EExtended strand (participates in β ladder)trans-94.5131.3174.5-179.70000109.5T207 L211 L259 F435T207-V437 HydrophobicContact CG2-CG1 3.82Å; L211-V437 HydrophobicContact CD1-CG2 3.92Å; L211-V437 HydrophobicContact CD2-CG2 4.07Å; L259-V437 HydrophobicContact CD1-CG1 4.29Å; L259-V437 HydrophobicContact CD2-CG2 4.43Å; F435-V437 PolarHBondContact O-N 2.96Å
438R96.9Very high94.8Very high87 Ų8748.6 Ų48.633%0.32824%0.235SC..EExtended strand (participates in β ladder)trans-13396.9170.2-70.2-61.5178.2-175.3-3.9110.2L259 Q260 I261 V436 P475 Y476 P477L259-R438 PolarHBondContact O-N 2.83Å; Q260-R438 WeakPolarHBondContact CA-O 3.32Å; Q260-R438 HydrophobicContact CB-CB 4.11Å; Q260-R438 HydrophobicContact CG-CB 4.04Å; I261-R438 PolarHBondContact N-O 2.96Å; V436-R438 HydrophobicContact CG1-CG 4.4Å; R438-P475 HydrophobicContact CB-CB 4.24Å; R438-Y476 PolarHBondContact NH1-O 3.31Å; R438-P477 PolarHBondContact NH1-O 2.98Å
439D97.6Very high95.1Very high4 Ų438.8 Ų38.82%0.02119%0.192CC..EExtended strand (participates in β ladder)trans-82.6163.6176.1-150.6-38.9000111N204 T207 I261 P475 Y476N204-D439 PolarHBondContact ND2-OD1 2.81Å; N204-D439 PolarHBondContact ND2-OD2 2.89Å; T207-D439 WeakPolarHBondContact CB-OD2 3.41Å; T207-D439 HydrophobicContact CG2-CB 4.4Å; T207-D439 VanDerWaalsContact CG2-OD2 3.31Å; T207-D439 WeakPolarHBondContact CG2-OD2 3.36Å; T207-D439 VanDerWaalsContact OG1-CG 3.25Å; T207-D439 PolarHBondContact OG1-OD2 3.41Å; I261-D439 HydrophobicContact CG1-CB 4.5Å; D439-P475 CarbonylContact O-C 3.51Å; D439-P475 VanDerWaalsContact O-CA 3.24Å; D439-P475 WeakPolarHBondContact O-CA 3.46Å; D439-Y476 HydrophobicContact CB-CD1 4.16Å; D439-Y476 HydrophobicContact CB-CE1 3.66Å; D439-Y476 HydrophobicContact CB-CE2 4.04Å; D439-Y476 WeakPolarHBondContact O-CD1 3.23Å; D439-Y476 PolarHBondContact O-N 3.04Å
440A97.6Very high95.2Very high2 Ų240.3 Ų40.32%0.01720%0.197CC..EExtended strand (participates in β ladder)trans-117.8135-166.400000113.6I261 V442 M473I261-A440 HydrophobicContact CB-CB 3.8Å; I261-A440 HydrophobicContact CG2-CB 3.71Å; A440-V442 PolarHBondContact O-N 2.83Å; A440-M473 HydrophobicContact CB-CE 4.07Å; A440-M473 HydrophobicContact CB-SD 3.87Å
441V98.1Very high94.8Very high9 Ų940.7 Ų40.76%0.05520%0.197CC..  trans-71.898.6178.5174.70000110.5Y443 F470 S471 R472 M473 G474 Y476 L545V441-Y443 WeakPolarHBondContact CG1-O 3.42Å; V441-F470 HydrophobicContact CG1-CB 4.13Å; V441-F470 HydrophobicContact CG2-CB 4.33Å; V441-S471 WeakPolarHBondContact CB-O 3.4Å; V441-R472 CarbonylContact O-C 3.56Å; V441-R472 WeakPolarHBondContact O-CA 3.06Å; V441-M473 PolarHBondContact O-N 2.7Å; V441-G474 WeakPolarHBondContact CG2-O 3.26Å; V441-G474 PolarHBondContact N-O 2.78Å; V441-Y476 HydrophobicContact CG2-CD1 3.82Å; V441-Y476 HydrophobicContact CG2-CG 4.43Å; V441-L545 HydrophobicContact CG2-CD2 3.41Å; V441-L545 VanDerWaalsContact CG2-CD2 3.41Å
442V96.9Very high94.4Very high11 Ų1137.1 Ų37.17%0.06718%0.184CC..SBendtrans-63.3-48.8177.4-1780000111.5V178 V264 F266 A440 M473 F502V178-V442 HydrophobicContact CG2-CG2 3.82Å; V264-V442 HydrophobicContact CB-CG2 4.44Å; V264-V442 HydrophobicContact CG1-CG2 4.21Å; V264-V442 HydrophobicContact CG2-CG2 4.46Å; F266-V442 HydrophobicContact CE1-CG1 4.12Å; A440-V442 PolarHBondContact O-N 2.83Å; V442-M473 HydrophobicContact CB-CE 4.38Å; V442-M473 HydrophobicContact CG2-CE 4.16Å; V442-F502 HydrophobicContact CG1-CE2 4.42Å; V442-F502 HydrophobicContact CG1-CZ 4.29Å; V442-F502 WeakPolarHBondContact O-CZ 3.2Å
443Y97.7Very high93.8Very high15 Ų1536.8 Ų36.86%0.05918%0.182CC..SBendtrans-104.4111.2-177.5-54-61.2000109.2F179 N181 F266 V441 L500 F502 L503 F511F179-Y443 WeakPolarHBondContact CA-OH 3.47Å; F179-Y443 WeakPolarHBondContact O-CE2 3.37Å; F179-Y443 PolarHBondContact O-OH 2.9Å; N181-Y443 HydrophobicContact CB-CD2 4.41Å; N181-Y443 HydrophobicContact CB-CE2 4.35Å; F266-Y443 WeakPolarHBondContact CZ-OH 3.25Å; V441-Y443 WeakPolarHBondContact CG1-O 3.42Å; Y443-L500 HydrophobicContact CD1-CD2 3.76Å; Y443-L500 HydrophobicContact CG-CD2 4.48Å; Y443-F502 AromaticContact CD1-CZ 3.83Å; Y443-F502 HydrophobicContact CD1-CZ 3.83Å; Y443-F502 HydrophobicContact CE1-CE2 4.39Å; Y443-F502 AromaticContact CE1-CZ 3.95Å; Y443-F502 HydrophobicContact CE1-CZ 3.95Å; Y443-L503 HydrophobicContact CE1-CD1 4.07Å; Y443-L503 HydrophobicContact CE1-CD2 4.3Å; Y443-F511 HydrophobicContact CD1-CD2 4.3Å; Y443-F511 AromaticContact CD1-CE2 3.55Å; Y443-F511 HydrophobicContact CD1-CE2 3.55Å; Y443-F511 HydrophobicContact CD1-CZ 4.23Å; Y443-F511 AromaticContact CD2-CE2 3.84Å; Y443-F511 HydrophobicContact CD2-CE2 3.84Å; Y443-F511 AromaticContact CE1-CD2 3.96Å; Y443-F511 HydrophobicContact CE1-CD2 3.96Å; Y443-F511 AromaticContact CE1-CE2 3.62Å; Y443-F511 HydrophobicContact CE1-CE2 3.62Å; Y443-F511 HydrophobicContact CE2-CD2 4.5Å; Y443-F511 AromaticContact CE2-CE2 3.89Å; Y443-F511 HydrophobicContact CE2-CE2 3.89Å; Y443-F511 AromaticContact CG-CE2 3.67Å; Y443-F511 HydrophobicContact CG-CE2 3.67Å; Y443-F511 HydrophobicContact CG-CZ 4.18Å; Y443-F511 AromaticContact CZ-CE2 3.79Å
444P97.6Very high93.2Very high8 Ų835.1 Ų35.15%0.05218%0.177CC..  trans-61.8152.9177.425.1-32.5000110.9F470 R472 Y497 G498 D499P444-F470 CarbonylContact C-O 3.57Å; P444-F470 WeakPolarHBondContact CA-O 3.32Å; P444-F470 WeakPolarHBondContact CB-O 3.47Å; P444-R472 HydrophobicContact CB-CB 4.46Å; P444-R472 HydrophobicContact CG-CB 4.34Å; P444-Y497 CarbonylContact O-C 3.56Å; P444-Y497 VanDerWaalsContact O-CA 3.28Å; P444-Y497 WeakPolarHBondContact O-CA 3.32Å; P444-G498 PolarHBondContact O-N 3.35Å; P444-D499 WeakPolarHBondContact CG-O 3.36Å
445I98.3Very high92.4Very high2 Ų238.3 Ų38.31%0.0119%0.186CC..EExtended strand (participates in β ladder)trans-128.3137.2179.1-59.2178000108.5L469 F470 I495 Y497 L516 L545 L551I445-L469 HydrophobicContact CG2-CD1 4.27Å; I445-L469 WeakPolarHBondContact O-CA 3.42Å; I445-L469 WeakPolarHBondContact O-CB 3.43Å; I445-L469 PolarHBondContact O-N 3.04Å; I445-F470 HydrophobicContact CB-CB 4.45Å; I445-F470 HydrophobicContact CB-CD2 4.19Å; I445-F470 HydrophobicContact CD1-CD2 4.45Å; I445-F470 PolarHBondContact N-O 3.37Å; I445-F470 PolarHBondContact O-N 3.23Å; I445-I495 HydrophobicContact CG2-CG2 3.79Å; I445-Y497 HydrophobicContact CG1-CD1 4.27Å; I445-L516 HydrophobicContact CD1-CD1 4.31Å; I445-L516 HydrophobicContact CG1-CD1 4.36Å; I445-L516 HydrophobicContact CG2-CD1 4.13Å; I445-L545 HydrophobicContact CD1-CD1 4.39Å; I445-L551 HydrophobicContact CD1-CB 4.45Å; I445-L551 HydrophobicContact CD1-CD2 4.35Å; I445-L551 HydrophobicContact CG2-CD2 4.11Å
446L97.4Very high91.5Very high17 Ų1743.3 Ų43.39%0.08921%0.209CC..EExtended strand (participates in β ladder)trans-135.4166.9179.860.967.8000112.6E448 K466 R467 V468 I495 N496L446-E448 HydrophobicContact CD1-CG 3.4Å; L446-E448 WeakPolarHBondContact CD1-OE1 3.48Å; L446-K466 HydrophobicContact CD2-CD 4.4Å; L446-R467 CarbonylContact C-O 3.51Å; L446-R467 VanDerWaalsContact CA-O 3.29Å; L446-R467 WeakPolarHBondContact CA-O 3.37Å; L446-R467 WeakPolarHBondContact CB-O 3.49Å; L446-V468 HydrophobicContact CB-CG2 4.49Å; L446-I495 WeakPolarHBondContact O-CA 3.1Å; L446-N496 HydrophobicContact CD1-CB 3.9Å; L446-N496 PolarHBondContact N-O 2.92Å; L446-N496 PolarHBondContact O-N 3.3Å
447V97.4Very high90.4Very high0 Ų047.9 Ų47.90%024%0.24CC..EExtended strand (participates in β ladder)trans-117.4132.3174.5167.10000109.9F449 K466 R467 L469 F484 F493 H494 I495 F543V447-F449 HydrophobicContact CG1-CD1 4.09Å; V447-K466 CarbonylContact O-C 3.59Å; V447-K466 WeakPolarHBondContact O-CA 3.45Å; V447-R467 PolarHBondContact N-O 3.31Å; V447-R467 PolarHBondContact O-N 2.89Å; V447-L469 HydrophobicContact CG2-CD1 3.61Å; V447-L469 HydrophobicContact CG2-CD2 4.24Å; V447-L469 HydrophobicContact CG2-CG 3.82Å; V447-F484 HydrophobicContact CG1-CE1 4.16Å; V447-F484 HydrophobicContact CG1-CZ 3.97Å; V447-F493 HydrophobicContact CG1-CB 4.41Å; V447-F493 HydrophobicContact CG1-CD2 3.7Å; V447-F493 HydrophobicContact CG1-CE2 4.28Å; V447-F493 HydrophobicContact CG1-CG 4.29Å; V447-F493 HydrophobicContact CG2-CE2 4.48Å; V447-H494 CarbonylContact C-O 3.57Å; V447-H494 VanDerWaalsContact CA-O 3.23Å; V447-H494 WeakPolarHBondContact CA-O 3.38Å; V447-I495 HydrophobicContact CG2-CG1 4.45Å; V447-F543 HydrophobicContact CG2-CE1 4.2Å; V447-F543 HydrophobicContact CG2-CE2 4.23Å; V447-F543 HydrophobicContact CG2-CZ 3.73Å
448E95.6Very high89.4Confident23 Ų2349.5 Ų49.511%0.10726%0.261CS..EExtended strand (participates in β ladder)trans-117.6132.1179.5-50.9-167.8-178.800111.9L446 H464 N465 K466 H494 N496L446-E448 HydrophobicContact CD1-CG 3.4Å; L446-E448 WeakPolarHBondContact CD1-OE1 3.48Å; E448-H464 IonicContact OE2-CE1 2.67Å; E448-H464 PolarHBondContact OE2-CE1 2.89Å; E448-H464 IonicContact OE2-NE2 2.73Å; E448-H464 PolarHBondContact OE2-NE2 3.5Å; E448-N465 WeakPolarHBondContact CA-O 3.49Å; E448-K466 VanDerWaalsContact CD-CE 3.42Å; E448-K466 VanDerWaalsContact CD-NZ 3.29Å; E448-K466 HydrophobicContact CG-CB 4.49Å; E448-K466 HydrophobicContact CG-CD 4.13Å; E448-K466 HydrophobicContact CG-CG 3.96Å; E448-K466 WeakPolarHBondContact OE1-CD 3.19Å; E448-K466 WeakPolarHBondContact OE1-CE 3.21Å; E448-K466 IonicContact OE1-NZ 2.9Å; E448-K466 PolarHBondContact OE1-NZ 3.03Å; E448-K466 IonicContact OE2-NZ 2.75Å; E448-K466 PolarHBondContact OE2-NZ 3.19Å; E448-H494 HydrophobicContact CB-CB 4.34Å; E448-H494 PolarHBondContact N-O 3.2Å; E448-H494 PolarHBondContact O-N 2.85Å; E448-N496 PolarHBondContact OE1-ND2 3.31Å; E448-N496 VanDerWaalsContact OE1-ND2 3.14Å; E448-N496 PolarHBondContact OE2-ND2 3.04Å
449F93.9Very high88.4Confident10 Ų1049.7 Ų49.74%0.04427%0.267CS..EExtended strand (participates in β ladder)trans-154.1140.3-176.259.6-78.8000112.7V447 N465 R467 F484 Y487 F493V447-F449 HydrophobicContact CG1-CD1 4.09Å; F449-N465 HydrophobicContact CD1-CB 4.31Å; F449-N465 HydrophobicContact CD2-CB 4.22Å; F449-N465 HydrophobicContact CE1-CB 3.93Å; F449-N465 HydrophobicContact CE2-CB 3.84Å; F449-N465 HydrophobicContact CG-CB 4.45Å; F449-N465 HydrophobicContact CZ-CB 3.69Å; F449-N465 PolarHBondContact N-O 3.27Å; F449-N465 PolarHBondContact O-N 2.77Å; F449-N465 PolarHBondContact O-ND2 2.95Å; F449-R467 HydrophobicContact CE1-CG 4.02Å; F449-R467 HydrophobicContact CZ-CG 4.4Å; F449-F484 HydrophobicContact CB-CD1 4.46Å; F449-F484 HydrophobicContact CB-CE1 4.05Å; F449-F484 HydrophobicContact CD1-CD1 4.31Å; F449-F484 AromaticContact CD1-CE1 3.77Å; F449-F484 HydrophobicContact CD1-CE1 3.77Å; F449-F484 AromaticContact CD2-CD1 3.93Å; F449-F484 HydrophobicContact CD2-CD1 3.93Å; F449-F484 HydrophobicContact CD2-CE1 4.16Å; F449-F484 HydrophobicContact CE1-CE1 4.23Å; F449-F484 HydrophobicContact CE2-CD1 4.19Å; F449-F484 AromaticContact CG-CD1 3.98Å; F449-F484 HydrophobicContact CG-CD1 3.98Å; F449-F484 AromaticContact CG-CE1 3.73Å; F449-F484 HydrophobicContact CG-CE1 3.73Å; F449-F484 HydrophobicContact CZ-CD1 4.5Å; F449-Y487 WeakPolarHBondContact CD2-OH 3.34Å; F449-F493 HydrophobicContact CB-CB 4Å
450T89.4Confident87.5Confident73 Ų7355.1 Ų55.145%0.44829%0.292SS..EExtended strand (participates in β ladder)trans-90.7127.6175.943.20000110.7H464 Y487T450-H464 HydrophobicContact CG2-CB 4.43Å; T450-Y487 VanDerWaalsContact C-OH 3.26Å; T450-Y487 PolarHBondContact O-OH 3.39Å
451R83.8Confident86.8Confident53 Ų5356.6 Ų56.620%0.230%0.302CS..EExtended strand (participates in β ladder)trans-120.6129.3177.1-170-171.660.981.7-8.8109.8K463 Y487R451-K463 PolarHBondContact N-O 3.28Å; R451-K463 PolarHBondContact O-N 3.35Å; R451-Y487 VanDerWaalsContact CA-OH 3.29Å; R451-Y487 WeakPolarHBondContact CA-OH 3.49Å; R451-Y487 VanDerWaalsContact CB-OH 3.32Å; R451-Y487 WeakPolarHBondContact CB-OH 3.34Å; R451-Y487 HydrophobicContact CG-CE2 4.4Å
452E80.8Confident86.1Confident137 Ų13761.9 Ų61.964%0.6433%0.33SS*.EExtended strand (participates in β ladder)trans-63.6135.5169.3-69.9175.1176.500111S461 L462E452-S461 CarbonylContact C-O 3.57Å; E452-S461 WeakPolarHBondContact CA-O 3.1Å; E452-L462 HydrophobicContact CG-CD2 3.61Å
453V79.3Confident85.6Confident27 Ų2767 Ų6716%0.16435%0.351CS..EExtended strand (participates in β ladder)trans-128.5123.5176.6-158.40000107.4H460 S461 K463V453-H460 CarbonylContact O-C 3.6Å; V453-H460 VanDerWaalsContact O-CA 3.31Å; V453-H460 WeakPolarHBondContact O-CA 3.47Å; V453-S461 PolarHBondContact N-O 3.32Å; V453-S461 PolarHBondContact O-N 2.71Å; V453-K463 HydrophobicContact CG2-CB 3.43Å; V453-K463 VanDerWaalsContact CG2-CB 3.43Å; V453-K463 HydrophobicContact CG2-CD 4.4Å
454E77.9Confident85.2Confident114 Ų11470.7 Ų70.753%0.53337%0.369SS..EExtended strand (participates in β ladder)trans-76.8121.7162.6-168.7168.2-156.900107.9E456 P457 G458 I459 H460E454-E456 VanDerWaalsContact CG-O 3.23Å; E454-E456 WeakPolarHBondContact CG-O 3.2Å; E454-P457 WeakPolarHBondContact OE1-CA 3.02Å; E454-G458 PolarHBondContact OE1-N 3.44Å; E454-I459 WeakPolarHBondContact CA-O 3.42Å; E454-H460 IonicContact OE1-CE1 2.62Å
455E76.1Confident84.9Confident135 Ų13571.9 Ų71.963%0.63138%0.375SS*.EExtended strand (participates in β ladder)trans-98.6-41.2-179.3-66-175.3175.500110.8I459 S461E455-I459 PolarHBondContact N-O 3.15Å; E455-S461 VanDerWaalsContact CD-OG 3.3Å; E455-S461 VanDerWaalsContact OE1-CB 3.25Å; E455-S461 WeakPolarHBondContact OE1-CB 3.48Å; E455-S461 PolarHBondContact OE1-OG 3.23Å
456E76.2Confident84.8Confident128 Ų12877.7 Ų77.760%0.59840%0.4SS*.EExtended strand (participates in β ladder)trans-133.7161.7167.2-63.8-170.6165.700108.6E454 G458 I459E454-E456 VanDerWaalsContact CG-O 3.23Å; E454-E456 WeakPolarHBondContact CG-O 3.2Å; E456-G458 PolarHBondContact O-N 2.88Å; E456-I459 HydrophobicContact CB-CB 4.29Å; E456-I459 HydrophobicContact CB-CD1 4.17Å; E456-I459 HydrophobicContact CB-CG1 4.33Å; E456-I459 PolarHBondContact O-N 3.07Å
457P73.9Confident84.7Confident127 Ų12782 Ų8283%0.82542%0.415SS*.THydrogen-bonded Turntrans-53.5113.2-176.8-28.336.8000113.4E454 I459E454-P457 WeakPolarHBondContact OE1-CA 3.02Å; P457-I459 VanDerWaalsContact C-N 3.35Å
458G74.8Confident84.6Confident57 Ų5786.1 Ų86.159%0.58844%0.44SS*.THydrogen-bonded Turntrans79.43.2-176.200000116.3E454 E456E454-G458 PolarHBondContact OE1-N 3.44Å; E456-G458 PolarHBondContact O-N 2.88Å
459I75.9Confident84.6Confident91 Ų9185 Ų8547%0.46744%0.435SS..EExtended strand (participates in β ladder)trans-102.6106.8171.7-57.8-172.6000109E454 E455 E456 P457E454-I459 WeakPolarHBondContact CA-O 3.42Å; E455-I459 PolarHBondContact N-O 3.15Å; E456-I459 HydrophobicContact CB-CB 4.29Å; E456-I459 HydrophobicContact CB-CD1 4.17Å; E456-I459 HydrophobicContact CB-CG1 4.33Å; E456-I459 PolarHBondContact O-N 3.07Å; P457-I459 VanDerWaalsContact C-N 3.35Å
460H78.1Confident84.8Confident118 Ų11884.5 Ų84.555%0.54643%0.433SS..EExtended strand (participates in β ladder)trans-106.7127.7-179.3-54.9-63000112.1V453 E454V453-H460 CarbonylContact O-C 3.6Å; V453-H460 VanDerWaalsContact O-CA 3.31Å; V453-H460 WeakPolarHBondContact O-CA 3.47Å; E454-H460 IonicContact OE1-CE1 2.62Å
461S83.6Confident85.2Confident33 Ų3383.7 Ų83.723%0.23143%0.43CS..EExtended strand (participates in β ladder)trans-113153.2174.283.70000111.8E452 V453 E455E452-S461 CarbonylContact C-O 3.57Å; E452-S461 WeakPolarHBondContact CA-O 3.1Å; V453-S461 PolarHBondContact N-O 3.32Å; V453-S461 PolarHBondContact O-N 2.71Å; E455-S461 VanDerWaalsContact CD-OG 3.3Å; E455-S461 VanDerWaalsContact OE1-CB 3.25Å; E455-S461 WeakPolarHBondContact OE1-CB 3.48Å; E455-S461 PolarHBondContact OE1-OG 3.23Å
462L83.6Confident85.8Confident121 Ų12185.2 Ų85.263%0.63444%0.435SS*.EExtended strand (participates in β ladder)trans-96.894.4175.8-76171.5000110.8E452 H464E452-L462 HydrophobicContact CG-CD2 3.61Å; L462-H464 PolarHBondContact O-N 3.32Å
463K86.3Confident86.6Confident117 Ų11780 Ų8051%0.50941%0.412SS..EExtended strand (participates in β ladder)trans-77.2114.8173.6-178.2163-176.3158.80110.4R451 V453 N465R451-K463 PolarHBondContact N-O 3.28Å; R451-K463 PolarHBondContact O-N 3.35Å; V453-K463 HydrophobicContact CG2-CB 3.43Å; V453-K463 VanDerWaalsContact CG2-CB 3.43Å; V453-K463 HydrophobicContact CG2-CD 4.4Å; K463-N465 PolarHBondContact O-ND2 2.92Å
464H89.8Confident87.4Confident93 Ų9379 Ų7943%0.43141%0.407SS..EExtended strand (participates in β ladder)trans-71.1134.9165.9-178.899.6000110.3E448 T450 L462 K466E448-H464 IonicContact OE2-CE1 2.67Å; E448-H464 PolarHBondContact OE2-CE1 2.89Å; E448-H464 IonicContact OE2-NE2 2.73Å; E448-H464 PolarHBondContact OE2-NE2 3.5Å; T450-H464 HydrophobicContact CG2-CB 4.43Å; L462-H464 PolarHBondContact O-N 3.32Å; H464-K466 WeakPolarHBondContact NE2-CE 3.45Å; H464-K466 WeakPolarHBondContact NE2-CG 3.45Å
465N91.8Very high88.3Confident33 Ų3375.8 Ų75.818%0.17640%0.396CS..EExtended strand (participates in β ladder)trans-128.8132.4-178.9-48.2-94.3000109.4E448 F449 K463E448-N465 WeakPolarHBondContact CA-O 3.49Å; F449-N465 HydrophobicContact CD1-CB 4.31Å; F449-N465 HydrophobicContact CD2-CB 4.22Å; F449-N465 HydrophobicContact CE1-CB 3.93Å; F449-N465 HydrophobicContact CE2-CB 3.84Å; F449-N465 HydrophobicContact CG-CB 4.45Å; F449-N465 HydrophobicContact CZ-CB 3.69Å; F449-N465 PolarHBondContact N-O 3.27Å; F449-N465 PolarHBondContact O-N 2.77Å; F449-N465 PolarHBondContact O-ND2 2.95Å; K463-N465 PolarHBondContact O-ND2 2.92Å
466K94.8Very high89.3Confident125 Ų12569.8 Ų69.854%0.54337%0.367SS..EExtended strand (participates in β ladder)trans-110.1139.8169.7-52.6-160.9177.4-151.80109.6L446 V447 E448 H464L446-K466 HydrophobicContact CD2-CD 4.4Å; V447-K466 CarbonylContact O-C 3.59Å; V447-K466 WeakPolarHBondContact O-CA 3.45Å; E448-K466 VanDerWaalsContact CD-CE 3.42Å; E448-K466 VanDerWaalsContact CD-NZ 3.29Å; E448-K466 HydrophobicContact CG-CB 4.49Å; E448-K466 HydrophobicContact CG-CD 4.13Å; E448-K466 HydrophobicContact CG-CG 3.96Å; E448-K466 WeakPolarHBondContact OE1-CD 3.19Å; E448-K466 WeakPolarHBondContact OE1-CE 3.21Å; E448-K466 IonicContact OE1-NZ 2.9Å; E448-K466 PolarHBondContact OE1-NZ 3.03Å; E448-K466 IonicContact OE2-NZ 2.75Å; E448-K466 PolarHBondContact OE2-NZ 3.19Å; H464-K466 WeakPolarHBondContact NE2-CE 3.45Å; H464-K466 WeakPolarHBondContact NE2-CG 3.45Å
467R95.2Very high90.2Very high108 Ų10865.6 Ų65.641%0.40835%0.351SS..EExtended strand (participates in β ladder)trans-136.8119174.8-74.5-176174.8166.3-5.3110.3L446 V447 F449 L469 I482 T483L446-R467 CarbonylContact C-O 3.51Å; L446-R467 VanDerWaalsContact CA-O 3.29Å; L446-R467 WeakPolarHBondContact CA-O 3.37Å; L446-R467 WeakPolarHBondContact CB-O 3.49Å; V447-R467 PolarHBondContact N-O 3.31Å; V447-R467 PolarHBondContact O-N 2.89Å; F449-R467 HydrophobicContact CE1-CG 4.02Å; F449-R467 HydrophobicContact CZ-CG 4.4Å; R467-L469 PolarHBondContact O-N 3.05Å; R467-I482 HydrophobicContact CB-CD1 4.36Å; R467-T483 PolarHBondContact NH1-O 3.16Å
468V95.9Very high91.3Very high85 Ų8561.6 Ų61.652%0.51532%0.321SS..EExtended strand (participates in β ladder)trans-63.9122.3174.2179.80000109.6L446L446-V468 HydrophobicContact CB-CG2 4.49Å
469L96Very high92.3Very high0 Ų067.9 Ų67.90%033%0.327CS..EExtended strand (participates in β ladder)trans-77.6-70.2164.6-71.3178.1000108I445 V447 R467 K480 I482 F543I445-L469 HydrophobicContact CG2-CD1 4.27Å; I445-L469 WeakPolarHBondContact O-CA 3.42Å; I445-L469 WeakPolarHBondContact O-CB 3.43Å; I445-L469 PolarHBondContact O-N 3.04Å; V447-L469 HydrophobicContact CG2-CD1 3.61Å; V447-L469 HydrophobicContact CG2-CD2 4.24Å; V447-L469 HydrophobicContact CG2-CG 3.82Å; R467-L469 PolarHBondContact O-N 3.05Å; L469-K480 HydrophobicContact CD2-CB 4.48Å; L469-K480 WeakPolarHBondContact O-CD 3.25Å; L469-K480 WeakPolarHBondContact O-CE 3.18Å; L469-K480 PolarHBondContact O-NZ 3.43Å; L469-I482 HydrophobicContact CD2-CD1 3.9Å; L469-I482 HydrophobicContact CD2-CG1 3.51Å; L469-F543 HydrophobicContact CD1-CB 4.14Å; L469-F543 HydrophobicContact CD1-CD1 3.67Å; L469-F543 HydrophobicContact CD1-CD2 3.94Å; L469-F543 HydrophobicContact CD1-CE1 3.98Å; L469-F543 HydrophobicContact CD1-CE2 4.23Å; L469-F543 HydrophobicContact CD1-CG 3.63Å; L469-F543 HydrophobicContact CD1-CZ 4.25Å; L469-F543 HydrophobicContact CD2-CB 4.43Å; L469-F543 HydrophobicContact CD2-CD2 3.54Å; L469-F543 HydrophobicContact CD2-CE2 3.91Å; L469-F543 HydrophobicContact CD2-CG 4.01Å; L469-F543 HydrophobicContact CG-CD2 4.42Å
470F97.8Very high93.4Very high0 Ų067 Ų670%032%0.32CS..EExtended strand (participates in β ladder)trans-113.9119.2-173.1-54.4-69000108.5V441 P444 I445 Q478 K480 F543 L545 L551V441-F470 HydrophobicContact CG1-CB 4.13Å; V441-F470 HydrophobicContact CG2-CB 4.33Å; P444-F470 CarbonylContact C-O 3.57Å; P444-F470 WeakPolarHBondContact CA-O 3.32Å; P444-F470 WeakPolarHBondContact CB-O 3.47Å; I445-F470 HydrophobicContact CB-CB 4.45Å; I445-F470 HydrophobicContact CB-CD2 4.19Å; I445-F470 HydrophobicContact CD1-CD2 4.45Å; I445-F470 PolarHBondContact N-O 3.37Å; I445-F470 PolarHBondContact O-N 3.23Å; F470-Q478 HydrophobicContact CD1-CB 4.01Å; F470-Q478 HydrophobicContact CE1-CB 3.6Å; F470-K480 HydrophobicContact CD1-CD 4.3Å; F470-K480 HydrophobicContact CE1-CB 4.4Å; F470-K480 HydrophobicContact CE1-CD 4.02Å; F470-K480 HydrophobicContact CE1-CG 4.09Å; F470-K480 HydrophobicContact CZ-CB 4.43Å; F470-F543 HydrophobicContact CE2-CB 4.36Å; F470-F543 HydrophobicContact CZ-CB 4.3Å; F470-L545 HydrophobicContact CB-CD2 4.33Å; F470-L545 HydrophobicContact CD1-CB 4.2Å; F470-L545 HydrophobicContact CD1-CD2 4.27Å; F470-L545 HydrophobicContact CD2-CB 4.22Å; F470-L545 HydrophobicContact CD2-CD2 4.37Å; F470-L545 HydrophobicContact CE1-CB 3.93Å; F470-L545 HydrophobicContact CE2-CB 3.95Å; F470-L545 HydrophobicContact CG-CB 4.36Å; F470-L545 HydrophobicContact CG-CD2 4.04Å; F470-L545 HydrophobicContact CZ-CB 3.8Å; F470-L551 HydrophobicContact CD2-CD1 4.24Å; F470-L551 HydrophobicContact CE2-CD1 3.59Å
471S96.8Very high94.2Very high55 Ų5564.3 Ų64.339%0.38531%0.312SS..  trans-82.7153.1-177.152.60000111.1V441 M473 G474V441-S471 WeakPolarHBondContact CB-O 3.4Å; S471-M473 PolarHBondContact O-N 3.01Å; S471-G474 PolarHBondContact O-N 3.21Å
472R96.8Very high94.8Very high85 Ų8563.6 Ų63.632%0.32131%0.305SS..THydrogen-bonded Turntrans-56.1137.6172.5-171.5171.5-179.5-132.8-2.6109.8V441 P444 G474 F502V441-R472 CarbonylContact O-C 3.56Å; V441-R472 WeakPolarHBondContact O-CA 3.06Å; P444-R472 HydrophobicContact CB-CB 4.46Å; P444-R472 HydrophobicContact CG-CB 4.34Å; R472-G474 PolarHBondContact O-N 2.67Å; R472-F502 VanDerWaalsContact NH2-CG 3.3Å
473M97.3Very high95.4Very high29 Ų2959.9 Ų59.914%0.14329%0.287CS..THydrogen-bonded Turntrans5315.1-170.8-60.4-6396.500115.8V264 S369 A440 V441 V442 S471V264-M473 HydrophobicContact CB-CE 4.25Å; V264-M473 HydrophobicContact CB-SD 4.44Å; V264-M473 HydrophobicContact CG2-CE 4.22Å; V264-M473 HydrophobicContact CG2-SD 4.23Å; S369-M473 WeakPolarHBondContact O-CG 3.31Å; A440-M473 HydrophobicContact CB-CE 4.07Å; A440-M473 HydrophobicContact CB-SD 3.87Å; V441-M473 PolarHBondContact O-N 2.7Å; V442-M473 HydrophobicContact CB-CE 4.38Å; V442-M473 HydrophobicContact CG2-CE 4.16Å; S471-M473 PolarHBondContact O-N 3.01Å
474G97.2Very high95.7Very high6 Ų654.3 Ų54.36%0.06226%0.263CS..  trans-65.3136.1169.300000110.8V441 S471 R472V441-G474 WeakPolarHBondContact CG2-O 3.26Å; V441-G474 PolarHBondContact N-O 2.78Å; S471-G474 PolarHBondContact O-N 3.21Å; R472-G474 PolarHBondContact O-N 2.67Å
475P96.8Very high95.6Very high46 Ų4654.4 Ų54.430%0.29927%0.267SS..EExtended strand (participates in β ladder)trans-79131-175.729.6-34.5000111.7R438 D439 Q478R438-P475 HydrophobicContact CB-CB 4.24Å; D439-P475 CarbonylContact O-C 3.51Å; D439-P475 VanDerWaalsContact O-CA 3.24Å; D439-P475 WeakPolarHBondContact O-CA 3.46Å; P475-Q478 WeakPolarHBondContact O-CG 3.5Å; P475-Q478 PolarHBondContact O-NE2 3.45Å
476Y96.6Very high95.2Very high8 Ų862.7 Ų62.73%0.03130%0.296CS..EExtended strand (participates in β ladder)trans-111.2169.7178.574.6-97.9000112.4N204 R438 D439 V441 L545 D546 G549N204-Y476 PolarHBondContact ND2-OH 2.79Å; N204-Y476 VanDerWaalsContact ND2-OH 3.09Å; R438-Y476 PolarHBondContact NH1-O 3.31Å; D439-Y476 HydrophobicContact CB-CD1 4.16Å; D439-Y476 HydrophobicContact CB-CE1 3.66Å; D439-Y476 HydrophobicContact CB-CE2 4.04Å; D439-Y476 WeakPolarHBondContact O-CD1 3.23Å; D439-Y476 PolarHBondContact O-N 3.04Å; V441-Y476 HydrophobicContact CG2-CD1 3.82Å; V441-Y476 HydrophobicContact CG2-CG 4.43Å; Y476-L545 HydrophobicContact CG-CD2 4.28Å; Y476-D546 VanDerWaalsContact CD2-O 3.29Å; Y476-D546 WeakPolarHBondContact CD2-O 3.21Å; Y476-G549 VanDerWaalsContact CE2-CA 3.47Å; Y476-G549 VanDerWaalsContact CE2-N 3.34Å
477P95.9Very high94.7Very high40 Ų4058 Ų5826%0.2628%0.275SS..SBendcis-60.8153-6.727.1-37.3000113.8R438 L545 E547R438-P477 PolarHBondContact NH1-O 2.98Å; P477-L545 CarbonylContact C-O 3.58Å; P477-L545 VanDerWaalsContact CA-O 3.25Å; P477-L545 WeakPolarHBondContact CA-O 3.2Å; P477-L545 WeakPolarHBondContact CB-O 3.34Å; P477-E547 HydrophobicContact CG-CG 4.14Å
478Q96.1Very high94.3Very high43 Ų4355.5 Ų55.520%0.20127%0.274CS..EExtended strand (participates in β ladder)trans-143.1144176.2-72.3-170.11700112.6F470 P475 L545F470-Q478 HydrophobicContact CD1-CB 4.01Å; F470-Q478 HydrophobicContact CE1-CB 3.6Å; P475-Q478 WeakPolarHBondContact O-CG 3.5Å; P475-Q478 PolarHBondContact O-NE2 3.45Å; Q478-L545 PolarHBondContact N-O 3.18Å; Q478-L545 PolarHBondContact O-N 3.36Å
479R97.1Very high94.1Very high190 Ų19057.9 Ų57.972%0.71728%0.279SS*.EExtended strand (participates in β ladder)trans-111.1138164.7-70.8-178.7-179.9167.7-0.5110.9F543 N544R479-F543 CarbonylContact C-O 3.47Å; R479-F543 WeakPolarHBondContact CA-O 3.42Å; R479-N544 HydrophobicContact CG-CB 3.95Å; R479-N544 WeakPolarHBondContact CG-OD1 3.48Å; R479-N544 PolarHBondContact NE-OD1 3.48Å
480K97.2Very high94Very high73 Ų7362 Ų6232%0.31730%0.301SS..EExtended strand (participates in β ladder)trans-139.8149177.7-74.8-172.3176.2177.60111.7L469 F470 F543L469-K480 HydrophobicContact CD2-CB 4.48Å; L469-K480 WeakPolarHBondContact O-CD 3.25Å; L469-K480 WeakPolarHBondContact O-CE 3.18Å; L469-K480 PolarHBondContact O-NZ 3.43Å; F470-K480 HydrophobicContact CD1-CD 4.3Å; F470-K480 HydrophobicContact CE1-CB 4.4Å; F470-K480 HydrophobicContact CE1-CD 4.02Å; F470-K480 HydrophobicContact CE1-CG 4.09Å; F470-K480 HydrophobicContact CZ-CB 4.43Å; K480-F543 PolarHBondContact N-O 2.91Å; K480-F543 PolarHBondContact O-N 2.93Å
481V96.8Very high93.8Very high61 Ų6163 Ų6337%0.3731%0.305SS..EExtended strand (participates in β ladder)trans-121.9127.2-179.7-172.50000109.2K540 A541 H542V481-K540 HydrophobicContact CG1-CB 3.85Å; V481-K540 HydrophobicContact CG1-CG 4.35Å; V481-A541 VanDerWaalsContact CA-O 3.31Å; V481-A541 WeakPolarHBondContact CA-O 3.26Å; V481-H542 WeakPolarHBondContact CG2-CE1 3.24Å; V481-H542 WeakPolarHBondContact CG2-ND1 3.48Å
482I95.6Very high93.8Very high18 Ų1864.3 Ų64.39%0.09231%0.308CS..EExtended strand (participates in β ladder)trans-104.4119171.6-63.3-63.9000108.8R467 L469 F484 K540 A541 F543R467-I482 HydrophobicContact CB-CD1 4.36Å; L469-I482 HydrophobicContact CD2-CD1 3.9Å; L469-I482 HydrophobicContact CD2-CG1 3.51Å; I482-F484 HydrophobicContact CB-CE2 4.41Å; I482-F484 HydrophobicContact CB-CZ 4.48Å; I482-F484 HydrophobicContact CG2-CD1 4.36Å; I482-F484 HydrophobicContact CG2-CD2 4.31Å; I482-F484 HydrophobicContact CG2-CE1 3.98Å; I482-F484 HydrophobicContact CG2-CE2 3.94Å; I482-F484 HydrophobicContact CG2-CZ 3.76Å; I482-K540 WeakPolarHBondContact O-CA 3.31Å; I482-A541 PolarHBondContact N-O 2.89Å; I482-A541 PolarHBondContact O-N 3.35Å; I482-F543 HydrophobicContact CB-CE2 4.04Å; I482-F543 HydrophobicContact CG1-CD2 4.29Å; I482-F543 HydrophobicContact CG1-CE2 3.83Å
483T95.2Very high93.7Very high42 Ų4260.2 Ų60.226%0.25829%0.293SS..EExtended strand (participates in β ladder)trans-89.8121.8169.2-42.50000110.6R467 N485 K537 I539 K540R467-T483 PolarHBondContact NH1-O 3.16Å; T483-N485 WeakPolarHBondContact CG2-OD1 3.46Å; T483-K537 WeakPolarHBondContact CG2-O 3.46Å; T483-I539 CarbonylContact C-O 3.59Å; T483-I539 WeakPolarHBondContact CA-O 3.46Å; T483-K540 HydrophobicContact CG2-CG 3.96Å
484F93.4Very high93.7Very high1 Ų162.2 Ų62.20%0.00430%0.301CS..EExtended strand (participates in β ladder)trans-94.8104.3168.9-55.8-85.7000108.6V447 F449 I482 Y487 F491 F493 G538 I539 A541V447-F484 HydrophobicContact CG1-CE1 4.16Å; V447-F484 HydrophobicContact CG1-CZ 3.97Å; F449-F484 HydrophobicContact CB-CD1 4.46Å; F449-F484 HydrophobicContact CB-CE1 4.05Å; F449-F484 HydrophobicContact CD1-CD1 4.31Å; F449-F484 AromaticContact CD1-CE1 3.77Å; F449-F484 HydrophobicContact CD1-CE1 3.77Å; F449-F484 AromaticContact CD2-CD1 3.93Å; F449-F484 HydrophobicContact CD2-CD1 3.93Å; F449-F484 HydrophobicContact CD2-CE1 4.16Å; F449-F484 HydrophobicContact CE1-CE1 4.23Å; F449-F484 HydrophobicContact CE2-CD1 4.19Å; F449-F484 AromaticContact CG-CD1 3.98Å; F449-F484 HydrophobicContact CG-CD1 3.98Å; F449-F484 AromaticContact CG-CE1 3.73Å; F449-F484 HydrophobicContact CG-CE1 3.73Å; F449-F484 HydrophobicContact CZ-CD1 4.5Å; I482-F484 HydrophobicContact CB-CE2 4.41Å; I482-F484 HydrophobicContact CB-CZ 4.48Å; I482-F484 HydrophobicContact CG2-CD1 4.36Å; I482-F484 HydrophobicContact CG2-CD2 4.31Å; I482-F484 HydrophobicContact CG2-CE1 3.98Å; I482-F484 HydrophobicContact CG2-CE2 3.94Å; I482-F484 HydrophobicContact CG2-CZ 3.76Å; F484-Y487 HydrophobicContact CB-CD2 3.68Å; F484-Y487 HydrophobicContact CB-CE2 3.95Å; F484-F491 HydrophobicContact CB-CE2 4.31Å; F484-F491 HydrophobicContact CB-CZ 3.71Å; F484-F491 AromaticContact CD1-CE2 3.95Å; F484-F491 HydrophobicContact CD1-CE2 3.95Å; F484-F491 HydrophobicContact CD1-CZ 4.15Å; F484-F491 HydrophobicContact CD2-CE2 4.41Å; F484-F491 AromaticContact CD2-CZ 3.97Å; F484-F491 HydrophobicContact CD2-CZ 3.97Å; F484-F491 HydrophobicContact CE1-CE2 4.33Å; F484-F491 AromaticContact CG-CE2 4Å; F484-F491 HydrophobicContact CG-CE2 4Å; F484-F491 AromaticContact CG-CZ 3.7Å; F484-F491 HydrophobicContact CG-CZ 3.7Å; F484-F493 HydrophobicContact CE1-CB 4.13Å; F484-F493 HydrophobicContact CE1-CD1 4.13Å; F484-F493 HydrophobicContact CE1-CG 4.13Å; F484-F493 AromaticContact CE2-CD1 3.81Å; F484-F493 HydrophobicContact CE2-CD1 3.81Å; F484-F493 AromaticContact CE2-CE1 3.69Å; F484-F493 HydrophobicContact CE2-CE1 3.69Å; F484-F493 HydrophobicContact CE2-CG 4.42Å; F484-F493 HydrophobicContact CE2-CZ 4.21Å; F484-F493 HydrophobicContact CZ-CB 4.14Å; F484-F493 AromaticContact CZ-CD1 3.44Å; F484-F493 HydrophobicContact CZ-CD1 3.44Å; F484-F493 VanDerWaalsContact CZ-CD1 3.44Å; F484-F493 HydrophobicContact CZ-CD2 4.05Å; F484-F493 AromaticContact CZ-CE1 3.7Å; F484-F493 HydrophobicContact CZ-CE1 3.7Å; F484-F493 HydrophobicContact CZ-CE2 4.28Å; F484-F493 AromaticContact CZ-CG 3.62Å; F484-F493 HydrophobicContact CZ-CG 3.62Å; F484-F493 HydrophobicContact CZ-CZ 4.11Å; F484-G538 WeakPolarHBondContact O-CA 3.4Å; F484-I539 HydrophobicContact CB-CB 4.42Å; F484-I539 PolarHBondContact N-O 2.9Å; F484-I539 PolarHBondContact O-N 3.13Å; F484-A541 HydrophobicContact CE2-CB 3.84Å
485N87.6Confident93.8Very high94 Ų9462.2 Ų62.250%0.50330%0.3SS..  trans-92.1150.3176.5-67.7-17.8000110.3T483 Y487T483-N485 WeakPolarHBondContact CG2-OD1 3.46Å; N485-Y487 WeakPolarHBondContact O-CD2 3.47Å
486R82.8Confident93.8Very high207 Ų20760.6 Ų60.678%0.78129%0.289SS*.SBendtrans68.426.9-179.1-47.9-176.3-178.5-168.8-0.8115.3
487Y85.8Confident93.9Very high28 Ų2860.6 Ų60.611%0.1129%0.289CS..  trans-108.5118.2166.5-63.7-92.7000109F449 T450 R451 F484 N485 F491 F528F449-Y487 WeakPolarHBondContact CD2-OH 3.34Å; T450-Y487 VanDerWaalsContact C-OH 3.26Å; T450-Y487 PolarHBondContact O-OH 3.39Å; R451-Y487 VanDerWaalsContact CA-OH 3.29Å; R451-Y487 WeakPolarHBondContact CA-OH 3.49Å; R451-Y487 VanDerWaalsContact CB-OH 3.32Å; R451-Y487 WeakPolarHBondContact CB-OH 3.34Å; R451-Y487 HydrophobicContact CG-CE2 4.4Å; F484-Y487 HydrophobicContact CB-CD2 3.68Å; F484-Y487 HydrophobicContact CB-CE2 3.95Å; N485-Y487 WeakPolarHBondContact O-CD2 3.47Å; Y487-F491 HydrophobicContact CD1-CB 3.96Å; Y487-F491 AromaticContact CD1-CD1 3.58Å; Y487-F491 HydrophobicContact CD1-CD1 3.58Å; Y487-F491 AromaticContact CD1-CD2 3.72Å; Y487-F491 HydrophobicContact CD1-CD2 3.72Å; Y487-F491 AromaticContact CD1-CE1 3.91Å; Y487-F491 HydrophobicContact CD1-CE1 3.91Å; Y487-F491 HydrophobicContact CD1-CE2 4.05Å; Y487-F491 AromaticContact CD1-CG 3.47Å; Y487-F491 HydrophobicContact CD1-CG 3.47Å; Y487-F491 VanDerWaalsContact CD1-CG 3.47Å; Y487-F491 HydrophobicContact CD1-CZ 4.14Å; Y487-F491 HydrophobicContact CD2-CE1 4.38Å; Y487-F491 HydrophobicContact CD2-CZ 4.22Å; Y487-F491 HydrophobicContact CE1-CB 4.36Å; Y487-F491 HydrophobicContact CE1-CD1 4.47Å; Y487-F491 AromaticContact CE1-CD2 3.8Å; Y487-F491 HydrophobicContact CE1-CD2 3.8Å; Y487-F491 HydrophobicContact CE1-CE2 4.17Å; Y487-F491 AromaticContact CE1-CG 3.97Å; Y487-F491 HydrophobicContact CE1-CG 3.97Å; Y487-F491 AromaticContact CG-CD1 3.8Å; Y487-F491 HydrophobicContact CG-CD1 3.8Å; Y487-F491 HydrophobicContact CG-CD2 4.33Å; Y487-F491 AromaticContact CG-CE1 3.67Å; Y487-F491 HydrophobicContact CG-CE1 3.67Å; Y487-F491 HydrophobicContact CG-CE2 4.23Å; Y487-F491 HydrophobicContact CG-CG 4.13Å; Y487-F491 AromaticContact CG-CZ 3.91Å; Y487-F491 HydrophobicContact CG-CZ 3.91Å; Y487-F528 WeakPolarHBondContact O-CE2 3.4Å; Y487-F528 VanDerWaalsContact O-CZ 3.32Å; Y487-F528 WeakPolarHBondContact O-CZ 3.48Å
488S86.3Confident93.9Very high54 Ų5459.3 Ų59.338%0.37828%0.282SS..  trans-116.41.9179.1540000113.2G525S488-G525 VanDerWaalsContact O-CA 3.27Å; S488-G525 WeakPolarHBondContact O-CA 3.45Å
489H90.8Very high93.8Very high136 Ų13663.3 Ų63.363%0.6331%0.305SS*.SBendtrans-138.6166.1-176.9-68.183.9000109.5V524H489-V524 WeakPolarHBondContact O-CG1 3.48Å
490D94.2Very high93.8Very high85 Ų8554.6 Ų54.646%0.45527%0.273SS..  trans-60.8132.4179.4-70.75.8000110.8L521 K522 G523 V524 G525D490-L521 VanDerWaalsContact CB-O 3.31Å; D490-L521 WeakPolarHBondContact CB-O 3.45Å; D490-K522 WeakPolarHBondContact OD2-CA 3.41Å; D490-G523 VanDerWaalsContact CG-N 3.35Å; D490-G523 PolarHBondContact OD1-N 2.92Å; D490-G523 PolarHBondContact OD2-N 3.21Å; D490-V524 WeakPolarHBondContact OD1-CA 3.2Å; D490-V524 WeakPolarHBondContact OD1-CB 3.42Å; D490-V524 PolarHBondContact OD1-N 2.84Å; D490-G525 PolarHBondContact OD1-N 3.17Å
491F94.5Very high93.6Very high22 Ų2254.1 Ų54.110%0.09629%0.289CS..  trans-148.8165.3-174.675.7-83.2000112.1F484 Y487 F493 L521 I539F484-F491 HydrophobicContact CB-CE2 4.31Å; F484-F491 HydrophobicContact CB-CZ 3.71Å; F484-F491 AromaticContact CD1-CE2 3.95Å; F484-F491 HydrophobicContact CD1-CE2 3.95Å; F484-F491 HydrophobicContact CD1-CZ 4.15Å; F484-F491 HydrophobicContact CD2-CE2 4.41Å; F484-F491 AromaticContact CD2-CZ 3.97Å; F484-F491 HydrophobicContact CD2-CZ 3.97Å; F484-F491 HydrophobicContact CE1-CE2 4.33Å; F484-F491 AromaticContact CG-CE2 4Å; F484-F491 HydrophobicContact CG-CE2 4Å; F484-F491 AromaticContact CG-CZ 3.7Å; F484-F491 HydrophobicContact CG-CZ 3.7Å; Y487-F491 HydrophobicContact CD1-CB 3.96Å; Y487-F491 AromaticContact CD1-CD1 3.58Å; Y487-F491 HydrophobicContact CD1-CD1 3.58Å; Y487-F491 AromaticContact CD1-CD2 3.72Å; Y487-F491 HydrophobicContact CD1-CD2 3.72Å; Y487-F491 AromaticContact CD1-CE1 3.91Å; Y487-F491 HydrophobicContact CD1-CE1 3.91Å; Y487-F491 HydrophobicContact CD1-CE2 4.05Å; Y487-F491 AromaticContact CD1-CG 3.47Å; Y487-F491 HydrophobicContact CD1-CG 3.47Å; Y487-F491 VanDerWaalsContact CD1-CG 3.47Å; Y487-F491 HydrophobicContact CD1-CZ 4.14Å; Y487-F491 HydrophobicContact CD2-CE1 4.38Å; Y487-F491 HydrophobicContact CD2-CZ 4.22Å; Y487-F491 HydrophobicContact CE1-CB 4.36Å; Y487-F491 HydrophobicContact CE1-CD1 4.47Å; Y487-F491 AromaticContact CE1-CD2 3.8Å; Y487-F491 HydrophobicContact CE1-CD2 3.8Å; Y487-F491 HydrophobicContact CE1-CE2 4.17Å; Y487-F491 AromaticContact CE1-CG 3.97Å; Y487-F491 HydrophobicContact CE1-CG 3.97Å; Y487-F491 AromaticContact CG-CD1 3.8Å; Y487-F491 HydrophobicContact CG-CD1 3.8Å; Y487-F491 HydrophobicContact CG-CD2 4.33Å; Y487-F491 AromaticContact CG-CE1 3.67Å; Y487-F491 HydrophobicContact CG-CE1 3.67Å; Y487-F491 HydrophobicContact CG-CE2 4.23Å; Y487-F491 HydrophobicContact CG-CG 4.13Å; Y487-F491 AromaticContact CG-CZ 3.91Å; Y487-F491 HydrophobicContact CG-CZ 3.91Å; F491-F493 HydrophobicContact CE2-CD1 4.19Å; F491-L521 HydrophobicContact CD1-CD1 4.17Å; F491-L521 HydrophobicContact CE1-CD1 3.6Å; F491-L521 HydrophobicContact CE2-CD1 4.16Å; F491-L521 HydrophobicContact CZ-CD1 3.59Å; F491-L521 WeakPolarHBondContact O-CB 3.49Å; F491-L521 PolarHBondContact O-N 3.11Å; F491-I539 HydrophobicContact CE1-CB 4.43Å; F491-I539 HydrophobicContact CE1-CG1 4.2Å
492N95.4Very high93.4Very high82 Ų8253.4 Ų53.444%0.43928%0.281SS..EExtended strand (participates in β ladder)trans-115.4148.6179.2-54.6-23.6000110.7T518 V519 K520N492-T518 HydrophobicContact CB-CG2 4.34Å; N492-V519 CarbonylContact C-O 3.52Å; N492-V519 VanDerWaalsContact CA-O 3.23Å; N492-V519 WeakPolarHBondContact CA-O 3.34Å; N492-K520 VanDerWaalsContact OD1-CA 3.29Å; N492-K520 WeakPolarHBondContact OD1-CA 3.4Å; N492-K520 VanDerWaalsContact OD1-CB 3.24Å; N492-K520 WeakPolarHBondContact OD1-CB 3.33Å; N492-K520 WeakPolarHBondContact OD1-CG 3.46Å
493F96.3Very high93.4Very high0 Ų053.3 Ų53.30%028%0.28CS..EExtended strand (participates in β ladder)trans-134.8163165.367.4-98.4000110.6V447 F449 F484 F491 I495 V519 L521 A541 F543 L553V447-F493 HydrophobicContact CG1-CB 4.41Å; V447-F493 HydrophobicContact CG1-CD2 3.7Å; V447-F493 HydrophobicContact CG1-CE2 4.28Å; V447-F493 HydrophobicContact CG1-CG 4.29Å; V447-F493 HydrophobicContact CG2-CE2 4.48Å; F449-F493 HydrophobicContact CB-CB 4Å; F484-F493 HydrophobicContact CE1-CB 4.13Å; F484-F493 HydrophobicContact CE1-CD1 4.13Å; F484-F493 HydrophobicContact CE1-CG 4.13Å; F484-F493 AromaticContact CE2-CD1 3.81Å; F484-F493 HydrophobicContact CE2-CD1 3.81Å; F484-F493 AromaticContact CE2-CE1 3.69Å; F484-F493 HydrophobicContact CE2-CE1 3.69Å; F484-F493 HydrophobicContact CE2-CG 4.42Å; F484-F493 HydrophobicContact CE2-CZ 4.21Å; F484-F493 HydrophobicContact CZ-CB 4.14Å; F484-F493 AromaticContact CZ-CD1 3.44Å; F484-F493 HydrophobicContact CZ-CD1 3.44Å; F484-F493 VanDerWaalsContact CZ-CD1 3.44Å; F484-F493 HydrophobicContact CZ-CD2 4.05Å; F484-F493 AromaticContact CZ-CE1 3.7Å; F484-F493 HydrophobicContact CZ-CE1 3.7Å; F484-F493 HydrophobicContact CZ-CE2 4.28Å; F484-F493 AromaticContact CZ-CG 3.62Å; F484-F493 HydrophobicContact CZ-CG 3.62Å; F484-F493 HydrophobicContact CZ-CZ 4.11Å; F491-F493 HydrophobicContact CE2-CD1 4.19Å; F493-I495 HydrophobicContact CE2-CG1 4.15Å; F493-V519 HydrophobicContact CD1-CB 4.17Å; F493-V519 HydrophobicContact CD1-CG1 4.3Å; F493-V519 HydrophobicContact CD2-CB 3.98Å; F493-V519 HydrophobicContact CD2-CG2 4.1Å; F493-V519 HydrophobicContact CE1-CB 3.87Å; F493-V519 HydrophobicContact CE1-CG1 3.63Å; F493-V519 HydrophobicContact CE2-CB 3.66Å; F493-V519 HydrophobicContact CE2-CG1 4.12Å; F493-V519 HydrophobicContact CE2-CG2 3.51Å; F493-V519 HydrophobicContact CG-CB 4.24Å; F493-V519 HydrophobicContact CZ-CB 3.61Å; F493-V519 HydrophobicContact CZ-CG1 3.53Å; F493-V519 HydrophobicContact CZ-CG2 3.78Å; F493-V519 PolarHBondContact N-O 3.2Å; F493-V519 PolarHBondContact O-N 2.92Å; F493-L521 HydrophobicContact CD1-CD1 4.38Å; F493-L521 HydrophobicContact CE1-CD1 4.17Å; F493-L521 HydrophobicContact CE1-CD2 4.31Å; F493-L521 HydrophobicContact CE1-CG 4.4Å; F493-A541 HydrophobicContact CE1-CB 4.33Å; F493-A541 HydrophobicContact CZ-CB 3.95Å; F493-F543 HydrophobicContact CE2-CE1 4.12Å; F493-F543 AromaticContact CE2-CZ 3.68Å; F493-F543 HydrophobicContact CE2-CZ 3.68Å; F493-F543 HydrophobicContact CZ-CE1 4.44Å; F493-F543 AromaticContact CZ-CZ 3.88Å; F493-F543 HydrophobicContact CZ-CZ 3.88Å; F493-L553 HydrophobicContact CZ-CD2 4.16Å
494H97.3Very high93.2Very high71 Ų7152.6 Ų52.633%0.32928%0.281SS..EExtended strand (participates in β ladder)trans-113.4143.5-177.7-59.182.5000110.2V447 E448 T517 T518V447-H494 CarbonylContact C-O 3.57Å; V447-H494 VanDerWaalsContact CA-O 3.23Å; V447-H494 WeakPolarHBondContact CA-O 3.38Å; E448-H494 HydrophobicContact CB-CB 4.34Å; E448-H494 PolarHBondContact N-O 3.2Å; E448-H494 PolarHBondContact O-N 2.85Å; H494-T517 CarbonylContact C-O 3.5Å; H494-T517 WeakPolarHBondContact CA-O 3.36Å; H494-T518 PolarHBondContact CD2-OG1 2.8Å; H494-T518 PolarHBondContact NE2-OG1 2.89Å; H494-T518 VanDerWaalsContact NE2-OG1 3.17Å
495I97.8Very high93.2Very high5 Ų557.6 Ų57.63%0.02631%0.314CS..EExtended strand (participates in β ladder)trans-108.1121.5167-49.2177.5000106.2I445 L446 V447 F493 L516 T517 V519 F543 L551I445-I495 HydrophobicContact CG2-CG2 3.79Å; L446-I495 WeakPolarHBondContact O-CA 3.1Å; V447-I495 HydrophobicContact CG2-CG1 4.45Å; F493-I495 HydrophobicContact CE2-CG1 4.15Å; I495-L516 HydrophobicContact CB-CB 4.35Å; I495-L516 HydrophobicContact CG2-CB 4.22Å; I495-L516 HydrophobicContact CG2-CD1 4.05Å; I495-L516 WeakPolarHBondContact O-CA 3.5Å; I495-L516 WeakPolarHBondContact O-CB 3.42Å; I495-L516 PolarHBondContact O-N 3.41Å; I495-T517 PolarHBondContact N-O 2.78Å; I495-T517 PolarHBondContact O-N 2.85Å; I495-V519 HydrophobicContact CD1-CG2 3.84Å; I495-V519 HydrophobicContact CG1-CG2 4.01Å; I495-F543 HydrophobicContact CD1-CD1 4.41Å; I495-F543 HydrophobicContact CD1-CE1 3.77Å; I495-F543 HydrophobicContact CG1-CE1 4.24Å; I495-L551 HydrophobicContact CD1-CD2 4.31Å; I495-L551 HydrophobicContact CG2-CD2 3.65Å
496N97.7Very high93.3Very high12 Ų1258 Ų586%0.06431%0.313CS..EExtended strand (participates in β ladder)trans-130.9165.2179-59.3-22000109.5L446 E448 Q514 N515L446-N496 HydrophobicContact CD1-CB 3.9Å; L446-N496 PolarHBondContact N-O 2.92Å; L446-N496 PolarHBondContact O-N 3.3Å; E448-N496 PolarHBondContact OE1-ND2 3.31Å; E448-N496 VanDerWaalsContact OE1-ND2 3.14Å; E448-N496 PolarHBondContact OE2-ND2 3.04Å; N496-Q514 WeakPolarHBondContact CA-O 3.47Å; N496-N515 WeakPolarHBondContact OD1-CA 3.36Å; N496-N515 PolarHBondContact OD1-OD1 2.95Å
497Y97.8Very high93.8Very high9 Ų950.5 Ų50.54%0.03529%0.288CS..EExtended strand (participates in β ladder)trans-67.3156161.6-65.2-81.2000110.4N181 Q182 P444 I445 F511 Q514 L516N181-Y497 WeakPolarHBondContact CB-OH 3.44Å; Q182-Y497 WeakPolarHBondContact CB-OH 3.46Å; Q182-Y497 HydrophobicContact CG-CE1 4.3Å; Q182-Y497 WeakPolarHBondContact CG-OH 3.31Å; Q182-Y497 PolarHBondContact N-OH 2.96Å; P444-Y497 CarbonylContact O-C 3.56Å; P444-Y497 VanDerWaalsContact O-CA 3.28Å; P444-Y497 WeakPolarHBondContact O-CA 3.32Å; I445-Y497 HydrophobicContact CG1-CD1 4.27Å; Y497-F511 AromaticContact CD1-CZ 3.87Å; Y497-F511 HydrophobicContact CD1-CZ 3.87Å; Y497-F511 AromaticContact CD2-CE1 3.61Å; Y497-F511 HydrophobicContact CD2-CE1 3.61Å; Y497-F511 AromaticContact CD2-CZ 3.72Å; Y497-F511 HydrophobicContact CD2-CZ 3.72Å; Y497-F511 AromaticContact CE1-CZ 3.71Å; Y497-F511 HydrophobicContact CE1-CZ 3.71Å; Y497-F511 AromaticContact CE2-CE1 3.59Å; Y497-F511 HydrophobicContact CE2-CE1 3.59Å; Y497-F511 AromaticContact CE2-CZ 3.54Å; Y497-F511 HydrophobicContact CE2-CZ 3.54Å; Y497-F511 HydrophobicContact CG-CE1 4.09Å; Y497-F511 AromaticContact CG-CZ 3.86Å; Y497-F511 HydrophobicContact CG-CZ 3.86Å; Y497-F511 AromaticContact CZ-CZ 3.51Å; Y497-Q514 WeakPolarHBondContact CD2-O 3.48Å; Y497-Q514 PolarHBondContact N-O 2.83Å; Y497-L516 HydrophobicContact CD1-CD1 4.48Å; Y497-L516 HydrophobicContact CD2-CD1 4.42Å; Y497-L516 HydrophobicContact CD2-CD2 4.3Å; Y497-L516 HydrophobicContact CD2-CG 4.08Å; Y497-L516 HydrophobicContact CE1-CD1 4.3Å; Y497-L516 HydrophobicContact CE1-CD2 4.44Å; Y497-L516 HydrophobicContact CE2-CD1 4.26Å; Y497-L516 HydrophobicContact CE2-CD2 3.49Å; Y497-L516 VanDerWaalsContact CE2-CD2 3.49Å; Y497-L516 HydrophobicContact CE2-CG 3.77Å
498G96.1Very high94.3Very high12 Ų1251.4 Ų51.412%0.12430%0.295CS..  trans-85.1-143.9176.900000112.4P444 L500P444-G498 PolarHBondContact O-N 3.35Å; G498-L500 PolarHBondContact O-N 2.85Å
499D94.6Very high94.7Very high127 Ų12755.7 Ų55.768%0.67930%0.303SS*.  trans-66.2122.5174.3-177.420.1000111.5P444 G501P444-D499 WeakPolarHBondContact CG-O 3.36Å; D499-G501 PolarHBondContact OD1-N 3.49Å
500L96.1Very high94.9Very high8 Ų849.7 Ų49.74%0.04228%0.275CS..  trans-115.110.6176.7-63.6179.1000112.1Y443 G498 F502 L503 L508 F511 Q514Y443-L500 HydrophobicContact CD1-CD2 3.76Å; Y443-L500 HydrophobicContact CG-CD2 4.48Å; G498-L500 PolarHBondContact O-N 2.85Å; L500-F502 HydrophobicContact CD2-CE1 4.11Å; L500-F502 HydrophobicContact CD2-CZ 4.48Å; L500-F502 PolarHBondContact O-N 3.05Å; L500-L503 HydrophobicContact CB-CD1 4.33Å; L500-L503 HydrophobicContact CD2-CD1 4.43Å; L500-L503 WeakPolarHBondContact O-CB 3.49Å; L500-L503 PolarHBondContact O-N 2.61Å; L500-L508 HydrophobicContact CB-CD2 3.8Å; L500-L508 HydrophobicContact CD1-CD2 4.39Å; L500-F511 HydrophobicContact CD1-CD1 4.04Å; L500-F511 HydrophobicContact CD1-CE1 3.62Å; L500-F511 HydrophobicContact CD1-CZ 3.97Å; L500-F511 HydrophobicContact CD2-CZ 4.48Å; L500-Q514 HydrophobicContact CD1-CG 4.01Å
501G94.1Very high94.9Very high63 Ų6345.9 Ų45.965%0.64926%0.255SS*.THydrogen-bonded Turntrans-641.1-177.700000116.1D499D499-G501 PolarHBondContact OD1-N 3.49Å
502F92.8Very high94.8Very high46 Ų4646.5 Ų46.520%0.20227%0.267CS..THydrogen-bonded Turntrans-85.1-12.416871.3-90.7000113.6V442 Y443 R472 L500V442-F502 HydrophobicContact CG1-CE2 4.42Å; V442-F502 HydrophobicContact CG1-CZ 4.29Å; V442-F502 WeakPolarHBondContact O-CZ 3.2Å; Y443-F502 AromaticContact CD1-CZ 3.83Å; Y443-F502 HydrophobicContact CD1-CZ 3.83Å; Y443-F502 HydrophobicContact CE1-CE2 4.39Å; Y443-F502 AromaticContact CE1-CZ 3.95Å; Y443-F502 HydrophobicContact CE1-CZ 3.95Å; R472-F502 VanDerWaalsContact NH2-CG 3.3Å; L500-F502 HydrophobicContact CD2-CE1 4.11Å; L500-F502 HydrophobicContact CD2-CZ 4.48Å; L500-F502 PolarHBondContact O-N 3.05Å
503L94.7Very high94.7Very high15 Ų1544.5 Ų44.58%0.07926%0.259CS..SBendtrans-86.7139.6173.1-62.7-178000109.6F266 Y443 L500 D507 L508 F511F266-L503 HydrophobicContact CE2-CD2 4.35Å; F266-L503 HydrophobicContact CZ-CD2 3.76Å; Y443-L503 HydrophobicContact CE1-CD1 4.07Å; Y443-L503 HydrophobicContact CE1-CD2 4.3Å; L500-L503 HydrophobicContact CB-CD1 4.33Å; L500-L503 HydrophobicContact CD2-CD1 4.43Å; L500-L503 WeakPolarHBondContact O-CB 3.49Å; L500-L503 PolarHBondContact O-N 2.61Å; L503-D507 HydrophobicContact CB-CB 3.92Å; L503-D507 HydrophobicContact CD2-CB 4.21Å; L503-L508 HydrophobicContact CB-CD2 3.91Å; L503-L508 HydrophobicContact CB-CG 3.82Å; L503-L508 HydrophobicContact CD1-CD2 3.96Å; L503-F511 HydrophobicContact CD1-CB 4.37Å; L503-F511 HydrophobicContact CD1-CD2 4.14Å; L503-F511 HydrophobicContact CD1-CG 4.32Å
504G91.8Very high94.6Very high27 Ų2748.8 Ų48.828%0.27828%0.279SS..  trans-64.9162.417200000111.9E506 D507 L508G504-E506 PolarHBondContact O-N 3.17Å; G504-E506 VanDerWaalsContact O-N 3.14Å; G504-D507 PolarHBondContact N-OD2 3.28Å; G504-D507 PolarHBondContact O-N 3.12Å; G504-D507 VanDerWaalsContact O-N 3.1Å; G504-L508 WeakPolarHBondContact O-CG 3.29Å; G504-L508 PolarHBondContact O-N 2.9Å
505P92.3Very high94.4Very high107 Ų10749 Ų4970%0.69528%0.283SS*.Hα-helixtrans-54-34.5175.4-2735.6000113.2R509P505-R509 WeakPolarHBondContact O-CG 3.29Å; P505-R509 PolarHBondContact O-N 2.99Å
506E90.9Very high94.3Very high103 Ų10349 Ų4948%0.48128%0.283SS..Hα-helixtrans-69.5-48.7174.7-63.1-54.1142.900112.6G504 L508 R509 V510G504-E506 PolarHBondContact O-N 3.17Å; G504-E506 VanDerWaalsContact O-N 3.14Å; E506-L508 VanDerWaalsContact C-N 3.25Å; E506-L508 PolarHBondContact O-N 3.13Å; E506-R509 PolarHBondContact O-N 2.75Å; E506-R509 IonicContact OE1-CZ 3.29Å; E506-R509 IonicContact OE1-NE 2.66Å; E506-R509 IonicContact OE1-NH2 3.08Å; E506-R509 PolarHBondContact OE1-NH2 2.84Å; E506-R509 IonicContact OE2-CZ 2.66Å; E506-R509 IonicContact OE2-NE 3.49Å; E506-R509 PolarHBondContact OE2-NE 2.88Å; E506-R509 IonicContact OE2-NH2 2.67Å; E506-R509 PolarHBondContact OE2-NH2 3.15Å; E506-V510 WeakPolarHBondContact O-CG2 3.38Å; E506-V510 PolarHBondContact O-N 3.11Å
507D93.6Very high94.3Very high48 Ų4849.4 Ų49.426%0.25729%0.286SS..Hα-helixtrans-60.1-35.5176.8-66.5-67.3000112.1L503 G504 V510 F511L503-D507 HydrophobicContact CB-CB 3.92Å; L503-D507 HydrophobicContact CD2-CB 4.21Å; G504-D507 PolarHBondContact N-OD2 3.28Å; G504-D507 PolarHBondContact O-N 3.12Å; G504-D507 VanDerWaalsContact O-N 3.1Å; D507-V510 CarbonylContact O-C 3.54Å; D507-V510 PolarHBondContact O-N 3.06Å; D507-F511 WeakPolarHBondContact O-CB 3.31Å; D507-F511 PolarHBondContact O-N 2.78Å
508L94.9Very high94.2Very high48 Ų4850 Ų5025%0.25129%0.29SS..Hα-helixtrans-63.6-38.1173.7-72.6168.2000112.3L500 L503 G504 E506 F511 G512L500-L508 HydrophobicContact CB-CD2 3.8Å; L500-L508 HydrophobicContact CD1-CD2 4.39Å; L503-L508 HydrophobicContact CB-CD2 3.91Å; L503-L508 HydrophobicContact CB-CG 3.82Å; L503-L508 HydrophobicContact CD1-CD2 3.96Å; G504-L508 WeakPolarHBondContact O-CG 3.29Å; G504-L508 PolarHBondContact O-N 2.9Å; E506-L508 VanDerWaalsContact C-N 3.25Å; E506-L508 PolarHBondContact O-N 3.13Å; L508-F511 PolarHBondContact O-N 3.42Å; L508-G512 PolarHBondContact O-N 2.96Å
509R94.7Very high94.3Very high144 Ų14449.4 Ų49.454%0.54328%0.284SS..Hα-helixtrans-69.4-37.2173-64.8-165.4-60.9-157.28.6112.1N110 P111 P505 E506N110-R509 PolarHBondContact ND2-O 3.49Å; P111-R509 HydrophobicContact CG-CB 3.75Å; P505-R509 WeakPolarHBondContact O-CG 3.29Å; P505-R509 PolarHBondContact O-N 2.99Å; E506-R509 PolarHBondContact O-N 2.75Å; E506-R509 IonicContact OE1-CZ 3.29Å; E506-R509 IonicContact OE1-NE 2.66Å; E506-R509 IonicContact OE1-NH2 3.08Å; E506-R509 PolarHBondContact OE1-NH2 2.84Å; E506-R509 IonicContact OE2-CZ 2.66Å; E506-R509 IonicContact OE2-NE 3.49Å; E506-R509 PolarHBondContact OE2-NE 2.88Å; E506-R509 IonicContact OE2-NH2 2.67Å; E506-R509 PolarHBondContact OE2-NH2 3.15Å
510V95.3Very high94.4Very high9 Ų946.2 Ų46.26%0.05527%0.265CS..Hα-helixtrans-69.6-33.6175.4171.70000112.1K106 N110 P111 H112 E506 D507K106-V510 PolarHBondContact NZ-O 3.35Å; N110-V510 PolarHBondContact ND2-O 2.87Å; P111-V510 HydrophobicContact CB-CG2 4.04Å; P111-V510 HydrophobicContact CG-CG2 4.25Å; H112-V510 VanDerWaalsContact CD2-CG2 3.42Å; H112-V510 WeakPolarHBondContact CD2-CG2 3.45Å; E506-V510 WeakPolarHBondContact O-CG2 3.38Å; E506-V510 PolarHBondContact O-N 3.11Å; D507-V510 CarbonylContact O-C 3.54Å; D507-V510 PolarHBondContact O-N 3.06Å
511F95.1Very high94.5Very high6 Ų646 Ų463%0.02626%0.263CS..Hα-helixtrans-66.6-42.4176.4-174.7-90.6000112N181 Y443 Y497 L500 L503 D507 L508N181-F511 HydrophobicContact CB-CD2 4.19Å; N181-F511 HydrophobicContact CB-CE2 3.62Å; N181-F511 HydrophobicContact CB-CZ 4.06Å; N181-F511 PolarHBondContact ND2-O 3.28Å; N181-F511 VanDerWaalsContact ND2-O 3.07Å; Y443-F511 HydrophobicContact CD1-CD2 4.3Å; Y443-F511 AromaticContact CD1-CE2 3.55Å; Y443-F511 HydrophobicContact CD1-CE2 3.55Å; Y443-F511 HydrophobicContact CD1-CZ 4.23Å; Y443-F511 AromaticContact CD2-CE2 3.84Å; Y443-F511 HydrophobicContact CD2-CE2 3.84Å; Y443-F511 AromaticContact CE1-CD2 3.96Å; Y443-F511 HydrophobicContact CE1-CD2 3.96Å; Y443-F511 AromaticContact CE1-CE2 3.62Å; Y443-F511 HydrophobicContact CE1-CE2 3.62Å; Y443-F511 HydrophobicContact CE2-CD2 4.5Å; Y443-F511 AromaticContact CE2-CE2 3.89Å; Y443-F511 HydrophobicContact CE2-CE2 3.89Å; Y443-F511 AromaticContact CG-CE2 3.67Å; Y443-F511 HydrophobicContact CG-CE2 3.67Å; Y443-F511 HydrophobicContact CG-CZ 4.18Å; Y443-F511 AromaticContact CZ-CE2 3.79Å; Y497-F511 AromaticContact CD1-CZ 3.87Å; Y497-F511 HydrophobicContact CD1-CZ 3.87Å; Y497-F511 AromaticContact CD2-CE1 3.61Å; Y497-F511 HydrophobicContact CD2-CE1 3.61Å; Y497-F511 AromaticContact CD2-CZ 3.72Å; Y497-F511 HydrophobicContact CD2-CZ 3.72Å; Y497-F511 AromaticContact CE1-CZ 3.71Å; Y497-F511 HydrophobicContact CE1-CZ 3.71Å; Y497-F511 AromaticContact CE2-CE1 3.59Å; Y497-F511 HydrophobicContact CE2-CE1 3.59Å; Y497-F511 AromaticContact CE2-CZ 3.54Å; Y497-F511 HydrophobicContact CE2-CZ 3.54Å; Y497-F511 HydrophobicContact CG-CE1 4.09Å; Y497-F511 AromaticContact CG-CZ 3.86Å; Y497-F511 HydrophobicContact CG-CZ 3.86Å; Y497-F511 AromaticContact CZ-CZ 3.51Å; L500-F511 HydrophobicContact CD1-CD1 4.04Å; L500-F511 HydrophobicContact CD1-CE1 3.62Å; L500-F511 HydrophobicContact CD1-CZ 3.97Å; L500-F511 HydrophobicContact CD2-CZ 4.48Å; L503-F511 HydrophobicContact CD1-CB 4.37Å; L503-F511 HydrophobicContact CD1-CD2 4.14Å; L503-F511 HydrophobicContact CD1-CG 4.32Å; D507-F511 WeakPolarHBondContact O-CB 3.31Å; D507-F511 PolarHBondContact O-N 2.78Å; L508-F511 PolarHBondContact O-N 3.42Å
512G92.3Very high94.5Very high34 Ų3448.2 Ų48.235%0.35126%0.255SS..  trans87.4-139176.500000113.4L508 Q514L508-G512 PolarHBondContact O-N 2.96Å; G512-Q514 PolarHBondContact O-N 2.92Å
513S91.6Very high94.5Very high40 Ų4047.1 Ų47.128%0.2826%0.257SS..  trans-60.1132.1-174.6-174.70000112.7N515 L644S513-N515 PolarHBondContact OG-N 3.48Å; S513-N515 PolarHBondContact OG-O 3.25Å; S513-L644 PolarHBondContact OG-O 2.91Å
514Q94.3Very high94.4Very high90 Ų9046.4 Ų46.442%0.42125%0.253SS..SBendtrans-91.2-6.3175.6-59-176.418.700112.7N496 Y497 L500 G512N496-Q514 WeakPolarHBondContact CA-O 3.47Å; Y497-Q514 WeakPolarHBondContact CD2-O 3.48Å; Y497-Q514 PolarHBondContact N-O 2.83Å; L500-Q514 HydrophobicContact CD1-CG 4.01Å; G512-Q514 PolarHBondContact O-N 2.92Å
515N94.8Very high94.4Very high75 Ų7545.6 Ų45.640%0.40125%0.245SC..EExtended strand (participates in β ladder)trans-101.9126.1179.5-50.8-58.9000108.8N496 S513 L644 D645N496-N515 WeakPolarHBondContact OD1-CA 3.36Å; N496-N515 PolarHBondContact OD1-OD1 2.95Å; S513-N515 PolarHBondContact OG-N 3.48Å; S513-N515 PolarHBondContact OG-O 3.25Å; N515-L644 HydrophobicContact CB-CB 4.03Å; N515-L644 HydrophobicContact CB-CD1 3.98Å; N515-L644 CarbonylContact O-C 3.54Å; N515-L644 VanDerWaalsContact O-C 3.22Å; N515-L644 WeakPolarHBondContact O-CB 3.33Å; N515-D645 PolarHBondContact O-N 3.41Å
516L95.4Very high94.4Very high5 Ų544.8 Ų44.83%0.02624%0.235CC..EExtended strand (participates in β ladder)trans-93-52-177.6-72.3167.7000111.6Q182 I445 I495 Y497 L551 L644 D645Q182-L516 HydrophobicContact CB-CD2 3.77Å; Q182-L516 HydrophobicContact CG-CD1 4.35Å; Q182-L516 HydrophobicContact CG-CD2 3.81Å; I445-L516 HydrophobicContact CD1-CD1 4.31Å; I445-L516 HydrophobicContact CG1-CD1 4.36Å; I445-L516 HydrophobicContact CG2-CD1 4.13Å; I495-L516 HydrophobicContact CB-CB 4.35Å; I495-L516 HydrophobicContact CG2-CB 4.22Å; I495-L516 HydrophobicContact CG2-CD1 4.05Å; I495-L516 WeakPolarHBondContact O-CA 3.5Å; I495-L516 WeakPolarHBondContact O-CB 3.42Å; I495-L516 PolarHBondContact O-N 3.41Å; Y497-L516 HydrophobicContact CD1-CD1 4.48Å; Y497-L516 HydrophobicContact CD2-CD1 4.42Å; Y497-L516 HydrophobicContact CD2-CD2 4.3Å; Y497-L516 HydrophobicContact CD2-CG 4.08Å; Y497-L516 HydrophobicContact CE1-CD1 4.3Å; Y497-L516 HydrophobicContact CE1-CD2 4.44Å; Y497-L516 HydrophobicContact CE2-CD1 4.26Å; Y497-L516 HydrophobicContact CE2-CD2 3.49Å; Y497-L516 VanDerWaalsContact CE2-CD2 3.49Å; Y497-L516 HydrophobicContact CE2-CG 3.77Å; L516-L551 HydrophobicContact CD1-CD2 4.31Å; L516-L644 PolarHBondContact O-N 2.8Å; L516-D645 HydrophobicContact CD2-CB 4.17Å; L516-D645 WeakPolarHBondContact CD2-OD2 3.18Å
517T96.8Very high94.5Very high21 Ų2140.1 Ų40.113%0.12921%0.214CC..EExtended strand (participates in β ladder)trans-158.2130.2-169.9-42.30000112.3H494 I495 V519 L641 V642H494-T517 CarbonylContact C-O 3.5Å; H494-T517 WeakPolarHBondContact CA-O 3.36Å; I495-T517 PolarHBondContact N-O 2.78Å; I495-T517 PolarHBondContact O-N 2.85Å; T517-V519 HydrophobicContact CG2-CG2 4.33Å; T517-L641 HydrophobicContact CG2-CB 4.04Å; T517-L641 HydrophobicContact CG2-CD2 4.13Å; T517-V642 CarbonylContact C-O 3.57Å; T517-V642 VanDerWaalsContact CA-O 3.27Å; T517-V642 WeakPolarHBondContact CA-O 3.2Å; T517-V642 WeakPolarHBondContact CG2-O 3.33Å
518T97.3Very high94.3Very high21 Ų2140.5 Ų40.513%0.12921%0.213CC..EExtended strand (participates in β ladder)trans-83.4121.3156.9-60.70000108.4N492 H494 K520 V642N492-T518 HydrophobicContact CB-CG2 4.34Å; H494-T518 PolarHBondContact CD2-OG1 2.8Å; H494-T518 PolarHBondContact NE2-OG1 2.89Å; H494-T518 VanDerWaalsContact NE2-OG1 3.17Å; T518-K520 HydrophobicContact CG2-CG 4.16Å; T518-V642 PolarHBondContact N-O 3.18Å; T518-V642 PolarHBondContact O-N 3.09Å
519V97.4Very high94.2Very high0 Ų045.5 Ų45.50%023%0.233CC..EExtended strand (participates in β ladder)trans-97.3119.2172.3-176.60000108N492 F493 I495 T517 L521 L553 V639 L641N492-V519 CarbonylContact C-O 3.52Å; N492-V519 VanDerWaalsContact CA-O 3.23Å; N492-V519 WeakPolarHBondContact CA-O 3.34Å; F493-V519 HydrophobicContact CD1-CB 4.17Å; F493-V519 HydrophobicContact CD1-CG1 4.3Å; F493-V519 HydrophobicContact CD2-CB 3.98Å; F493-V519 HydrophobicContact CD2-CG2 4.1Å; F493-V519 HydrophobicContact CE1-CB 3.87Å; F493-V519 HydrophobicContact CE1-CG1 3.63Å; F493-V519 HydrophobicContact CE2-CB 3.66Å; F493-V519 HydrophobicContact CE2-CG1 4.12Å; F493-V519 HydrophobicContact CE2-CG2 3.51Å; F493-V519 HydrophobicContact CG-CB 4.24Å; F493-V519 HydrophobicContact CZ-CB 3.61Å; F493-V519 HydrophobicContact CZ-CG1 3.53Å; F493-V519 HydrophobicContact CZ-CG2 3.78Å; F493-V519 PolarHBondContact N-O 3.2Å; F493-V519 PolarHBondContact O-N 2.92Å; I495-V519 HydrophobicContact CD1-CG2 3.84Å; I495-V519 HydrophobicContact CG1-CG2 4.01Å; T517-V519 HydrophobicContact CG2-CG2 4.33Å; V519-L521 HydrophobicContact CG1-CD2 3.86Å; V519-L553 HydrophobicContact CG1-CD2 3.69Å; V519-L553 HydrophobicContact CG2-CD2 3.99Å; V519-V639 HydrophobicContact CG1-CG1 3.83Å; V519-L641 HydrophobicContact CB-CD2 4.39Å; V519-L641 HydrophobicContact CG1-CD2 4.14Å; V519-L641 HydrophobicContact CG2-CD2 3.83Å
520K97.4Very high94Very high61 Ų6144 Ų4427%0.26523%0.23SC..EExtended strand (participates in β ladder)trans-105.1131.5174-46.1177.7-166.7160.30109.3N492 T518 E640N492-K520 VanDerWaalsContact OD1-CA 3.29Å; N492-K520 WeakPolarHBondContact OD1-CA 3.4Å; N492-K520 VanDerWaalsContact OD1-CB 3.24Å; N492-K520 WeakPolarHBondContact OD1-CB 3.33Å; N492-K520 WeakPolarHBondContact OD1-CG 3.46Å; T518-K520 HydrophobicContact CG2-CG 4.16Å; K520-E640 HydrophobicContact CB-CB 4.26Å; K520-E640 WeakPolarHBondContact CD-OE1 3.37Å; K520-E640 WeakPolarHBondContact CE-OE1 3.34Å; K520-E640 PolarHBondContact N-O 2.86Å; K520-E640 IonicContact NZ-OE1 2.8Å; K520-E640 PolarHBondContact NZ-OE1 3.45Å; K520-E640 PolarHBondContact O-N 3.37Å
521L96.4Very high93.7Very high3 Ų345.3 Ų45.32%0.01624%0.235CC..EExtended strand (participates in β ladder)trans-106.5137.8-179.3-55.8-176.6000111.1D490 F491 F493 V519 V524 I539 V556 I637 G638 V639D490-L521 VanDerWaalsContact CB-O 3.31Å; D490-L521 WeakPolarHBondContact CB-O 3.45Å; F491-L521 HydrophobicContact CD1-CD1 4.17Å; F491-L521 HydrophobicContact CE1-CD1 3.6Å; F491-L521 HydrophobicContact CE2-CD1 4.16Å; F491-L521 HydrophobicContact CZ-CD1 3.59Å; F491-L521 WeakPolarHBondContact O-CB 3.49Å; F491-L521 PolarHBondContact O-N 3.11Å; F493-L521 HydrophobicContact CD1-CD1 4.38Å; F493-L521 HydrophobicContact CE1-CD1 4.17Å; F493-L521 HydrophobicContact CE1-CD2 4.31Å; F493-L521 HydrophobicContact CE1-CG 4.4Å; V519-L521 HydrophobicContact CG1-CD2 3.86Å; L521-V524 HydrophobicContact CB-CG2 3.92Å; L521-I539 HydrophobicContact CD1-CG2 4.13Å; L521-V556 HydrophobicContact CD1-CG1 4.04Å; L521-V556 HydrophobicContact CD2-CB 4.19Å; L521-V556 HydrophobicContact CD2-CG1 4.01Å; L521-V556 HydrophobicContact CD2-CG2 3.89Å; L521-I637 HydrophobicContact CB-CG2 3.91Å; L521-I637 HydrophobicContact CD2-CG2 4.29Å; L521-I637 HydrophobicContact CG-CG2 4.49Å; L521-G638 CarbonylContact C-O 3.53Å; L521-G638 WeakPolarHBondContact CA-O 3.38Å; L521-V639 HydrophobicContact CD2-CG2 4.05Å
522K95.3Very high93.3Very high109 Ų10949.5 Ų49.547%0.47426%0.262SS..EExtended strand (participates in β ladder)trans-130.3138.1-176.4-73.1173.5172.3170.30111.8D490 G638 E640D490-K522 WeakPolarHBondContact OD2-CA 3.41Å; K522-G638 PolarHBondContact N-O 3.41Å; K522-G638 PolarHBondContact O-N 2.9Å; K522-E640 IonicContact NZ-OE2 2.67Å; K522-E640 PolarHBondContact NZ-OE2 2.92Å
523G92.6Very high93Very high23 Ų2354.2 Ų54.224%0.23728%0.28CS..SBendtrans80.912.6-17900000114.5D490 G525 D526 S527D490-G523 VanDerWaalsContact CG-N 3.35Å; D490-G523 PolarHBondContact OD1-N 2.92Å; D490-G523 PolarHBondContact OD2-N 3.21Å; G523-G525 VanDerWaalsContact C-N 3.34Å; G523-D526 PolarHBondContact O-N 3Å; G523-S527 PolarHBondContact O-N 3.25Å; G523-S527 VanDerWaalsContact O-N 3.12Å
524V93Very high93Very high0 Ų054.6 Ų54.60%028%0.275CS..Hα-helixtrans-57.2-50.5172.7176.60000109.4H489 D490 L521 D526 S527 F528 I539 I637H489-V524 WeakPolarHBondContact O-CG1 3.48Å; D490-V524 WeakPolarHBondContact OD1-CA 3.2Å; D490-V524 WeakPolarHBondContact OD1-CB 3.42Å; D490-V524 PolarHBondContact OD1-N 2.84Å; L521-V524 HydrophobicContact CB-CG2 3.92Å; V524-D526 VanDerWaalsContact C-N 3.28Å; V524-D526 PolarHBondContact O-N 3.4Å; V524-S527 WeakPolarHBondContact O-CB 3.35Å; V524-S527 PolarHBondContact O-N 2.9Å; V524-S527 VanDerWaalsContact O-N 3.15Å; V524-S527 PolarHBondContact O-OG 2.86Å; V524-F528 HydrophobicContact CG1-CE2 4.26Å; V524-F528 WeakPolarHBondContact O-CD2 3.37Å; V524-F528 PolarHBondContact O-N 2.94Å; V524-I539 HydrophobicContact CG1-CD1 3.89Å; V524-I539 HydrophobicContact CG1-CG1 4.06Å; V524-I637 HydrophobicContact CG2-CD1 4.36Å; V524-I637 HydrophobicContact CG2-CG1 4.48Å; V524-I637 HydrophobicContact CG2-CG2 3.72Å
525G91.3Very high92.8Very high11 Ų1156.1 Ų56.111%0.11328%0.282CS..Hα-helixtrans-63.7-31.1-179.400000113.9S488 D490 G523 F528 K529S488-G525 VanDerWaalsContact O-CA 3.27Å; S488-G525 WeakPolarHBondContact O-CA 3.45Å; D490-G525 PolarHBondContact OD1-N 3.17Å; G523-G525 VanDerWaalsContact C-N 3.34Å; G525-F528 PolarHBondContact O-N 2.95Å; G525-K529 WeakPolarHBondContact O-CG 3.37Å; G525-K529 PolarHBondContact O-N 3.28Å
526D92.6Very high92.6Very high89 Ų8954.3 Ų54.348%0.47628%0.275SS..Hα-helixtrans-73.7-31.7176.5-61.9-47.3000112.1G523 V524 F528 K529 K530G523-D526 PolarHBondContact O-N 3Å; V524-D526 VanDerWaalsContact C-N 3.28Å; V524-D526 PolarHBondContact O-N 3.4Å; D526-F528 VanDerWaalsContact C-N 3.28Å; D526-F528 PolarHBondContact O-N 2.85Å; D526-K529 PolarHBondContact O-N 2.93Å; D526-K529 WeakPolarHBondContact OD1-CD 3.48Å; D526-K529 WeakPolarHBondContact OD1-CE 3.34Å; D526-K529 IonicContact OD1-NZ 3.37Å; D526-K529 PolarHBondContact OD1-NZ 3.38Å; D526-K530 PolarHBondContact O-N 3.48Å
527S92.1Very high92.6Very high5 Ų556.4 Ų56.44%0.03528%0.284CS..Hα-helixtrans-60.3-36.2171.680.20000112.7G523 V524 K530 Y531 S558 F560G523-S527 PolarHBondContact O-N 3.25Å; G523-S527 VanDerWaalsContact O-N 3.12Å; V524-S527 WeakPolarHBondContact O-CB 3.35Å; V524-S527 PolarHBondContact O-N 2.9Å; V524-S527 VanDerWaalsContact O-N 3.15Å; V524-S527 PolarHBondContact O-OG 2.86Å; S527-K530 PolarHBondContact O-N 2.97Å; S527-Y531 PolarHBondContact O-N 3.33Å; S527-S558 WeakPolarHBondContact OG-CB 3.33Å; S527-S558 PolarHBondContact OG-OG 2.86Å; S527-F560 WeakPolarHBondContact O-CZ 3.17Å
528F90.8Very high92.4Very high57 Ų5755.6 Ų55.625%0.2528%0.28CS..Hα-helixtrans-71.6-39.6175-79.9-101.6000112.3Y487 V524 G525 D526 K530 Y531 S536 I539 F560Y487-F528 WeakPolarHBondContact O-CE2 3.4Å; Y487-F528 VanDerWaalsContact O-CZ 3.32Å; Y487-F528 WeakPolarHBondContact O-CZ 3.48Å; V524-F528 HydrophobicContact CG1-CE2 4.26Å; V524-F528 WeakPolarHBondContact O-CD2 3.37Å; V524-F528 PolarHBondContact O-N 2.94Å; G525-F528 PolarHBondContact O-N 2.95Å; D526-F528 VanDerWaalsContact C-N 3.28Å; D526-F528 PolarHBondContact O-N 2.85Å; F528-K530 PolarHBondContact O-N 3.43Å; F528-Y531 CarbonylContact O-C 3.47Å; F528-Y531 PolarHBondContact O-N 3.44Å; F528-S536 WeakPolarHBondContact CZ-OG 3.34Å; F528-I539 HydrophobicContact CE2-CD1 4.27Å; F528-F560 HydrophobicContact CB-CZ 4.46Å; F528-F560 AromaticContact CD1-CE1 3.78Å; F528-F560 HydrophobicContact CD1-CE1 3.78Å; F528-F560 HydrophobicContact CD1-CZ 4.24Å; F528-F560 HydrophobicContact CD2-CE1 4.22Å; F528-F560 AromaticContact CD2-CZ 3.85Å; F528-F560 HydrophobicContact CD2-CZ 3.85Å; F528-F560 AromaticContact CE1-CE1 3.95Å; F528-F560 HydrophobicContact CE1-CE1 3.95Å; F528-F560 HydrophobicContact CE1-CZ 4.48Å; F528-F560 HydrophobicContact CE2-CE1 4.36Å; F528-F560 HydrophobicContact CE2-CZ 4.11Å; F528-F560 AromaticContact CG-CE1 3.94Å; F528-F560 HydrophobicContact CG-CE1 3.94Å; F528-F560 AromaticContact CG-CZ 3.92Å; F528-F560 HydrophobicContact CG-CZ 3.92Å; F528-F560 HydrophobicContact CZ-CE1 4.24Å; F528-F560 HydrophobicContact CZ-CZ 4.42Å
529K91.6Very high92.4Very high152 Ų15254.6 Ų54.666%0.66127%0.274SS*.Hα-helixtrans-62.5-28.5174.1-63.8169.5-157.6164.50112.7G525 D526G525-K529 WeakPolarHBondContact O-CG 3.37Å; G525-K529 PolarHBondContact O-N 3.28Å; D526-K529 PolarHBondContact O-N 2.93Å; D526-K529 WeakPolarHBondContact OD1-CD 3.48Å; D526-K529 WeakPolarHBondContact OD1-CE 3.34Å; D526-K529 IonicContact OD1-NZ 3.37Å; D526-K529 PolarHBondContact OD1-NZ 3.38Å
530K90.7Very high92.4Very high112 Ų11256.4 Ų56.449%0.48728%0.282SS..Hα-helixtrans-75.9-25.4178.5-164.9-178.1-179.5-164.90113.2D526 S527 F528 E635D526-K530 PolarHBondContact O-N 3.48Å; S527-K530 PolarHBondContact O-N 2.97Å; F528-K530 PolarHBondContact O-N 3.43Å; K530-E635 HydrophobicContact CD-CG 4.38Å; K530-E635 WeakPolarHBondContact CD-OE2 3.33Å; K530-E635 IonicContact NZ-OE1 2.67Å; K530-E635 PolarHBondContact NZ-OE1 3.41Å; K530-E635 IonicContact NZ-OE2 3.92Å; K530-E635 PolarHBondContact NZ-OE2 3.18Å
531Y88.8Confident92.4Very high38 Ų3853.5 Ų53.515%0.14927%0.269CS..  trans-134.459.6-177.4-61.5-67.2000112.7S527 F528 D533 Y534 F560 M633 E635S527-Y531 PolarHBondContact O-N 3.33Å; F528-Y531 CarbonylContact O-C 3.47Å; F528-Y531 PolarHBondContact O-N 3.44Å; Y531-D533 VanDerWaalsContact C-N 3.28Å; Y531-D533 PolarHBondContact O-N 3Å; Y531-Y534 HydrophobicContact CD1-CD2 4.05Å; Y531-Y534 AromaticContact CD1-CE2 3.99Å; Y531-Y534 HydrophobicContact CD1-CE2 3.99Å; Y531-Y534 HydrophobicContact CD1-CG 4.43Å; Y531-Y534 HydrophobicContact CG-CD2 4.47Å; Y531-Y534 PolarHBondContact O-N 3.48Å; Y531-F560 AromaticContact CD2-CD2 3.88Å; Y531-F560 HydrophobicContact CD2-CD2 3.88Å; Y531-F560 HydrophobicContact CD2-CE2 4.12Å; Y531-F560 HydrophobicContact CD2-CG 4.46Å; Y531-F560 HydrophobicContact CG-CD2 4.39Å; Y531-M633 HydrophobicContact CD1-CB 4.34Å; Y531-M633 HydrophobicContact CD1-CG 3.92Å; Y531-M633 HydrophobicContact CD2-CB 4.37Å; Y531-M633 HydrophobicContact CE1-CB 4.1Å; Y531-M633 HydrophobicContact CE1-CE 3.99Å; Y531-M633 HydrophobicContact CE1-CG 3.61Å; Y531-M633 HydrophobicContact CE1-SD 4.08Å; Y531-M633 HydrophobicContact CE2-CB 4.1Å; Y531-M633 HydrophobicContact CG-CB 4.49Å; Y531-E635 HydrophobicContact CD2-CG 4.28Å; Y531-E635 HydrophobicContact CE2-CG 3.69Å; Y531-E635 WeakPolarHBondContact CE2-OE1 3.35Å; Y531-E635 PolarHBondContact OH-OE1 2.86Å
532P86.1Confident92.4Very high94 Ų9455.7 Ų55.761%0.6128%0.279SS*.THydrogen-bonded Turntrans-64-32.4-175.927.1-34.4000112.9Y534P532-Y534 VanDerWaalsContact C-N 3.3Å; P532-Y534 PolarHBondContact O-N 3.4Å
533D87.9Confident92.6Very high133 Ų13350.6 Ų50.671%0.71126%0.257SS*.THydrogen-bonded Turntrans-90.117.2-177.3-44.1-68.6000113.7Y531 T562Y531-D533 VanDerWaalsContact C-N 3.28Å; Y531-D533 PolarHBondContact O-N 3Å; D533-T562 PolarHBondContact O-OG1 2.75Å
534Y90.1Very high92.8Very high47 Ų4750.3 Ų50.318%0.18425%0.25CS..SBendtrans-121.7139.7-178.5-67.2-122.4000111.4Y531 P532 S536 F560 T562 M633Y531-Y534 HydrophobicContact CD1-CD2 4.05Å; Y531-Y534 AromaticContact CD1-CE2 3.99Å; Y531-Y534 HydrophobicContact CD1-CE2 3.99Å; Y531-Y534 HydrophobicContact CD1-CG 4.43Å; Y531-Y534 HydrophobicContact CG-CD2 4.47Å; Y531-Y534 PolarHBondContact O-N 3.48Å; P532-Y534 VanDerWaalsContact C-N 3.3Å; P532-Y534 PolarHBondContact O-N 3.4Å; Y534-S536 PolarHBondContact O-N 3.47Å; Y534-F560 HydrophobicContact CD1-CB 4.29Å; Y534-F560 HydrophobicContact CG-CB 4.35Å; Y534-T562 HydrophobicContact CD1-CG2 3.67Å; Y534-T562 HydrophobicContact CD2-CG2 4.39Å; Y534-T562 HydrophobicContact CE1-CG2 3.36Å; Y534-T562 HydrophobicContact CE2-CG2 4.13Å; Y534-T562 HydrophobicContact CG-CG2 4.16Å; Y534-M633 HydrophobicContact CD1-CG 3.96Å; Y534-M633 HydrophobicContact CE1-CE 3.97Å; Y534-M633 HydrophobicContact CE1-CG 3.5Å; Y534-M633 VanDerWaalsContact OH-CE 3.27Å; Y534-M633 WeakPolarHBondContact OH-CE 3.22Å
535E90.4Very high93Very high122 Ų12250.5 Ų50.557%0.5725%0.251SS*.EExtended strand (participates in β ladder)trans-74.2115.7176.5-163.3-151.5140.100110.4K537 F560 E561E535-K537 PolarHBondContact O-N 2.83Å; E535-K537 IonicContact OE1-NZ 2.73Å; E535-K537 PolarHBondContact OE1-NZ 3.42Å; E535-K537 IonicContact OE2-NZ 2.65Å; E535-K537 PolarHBondContact OE2-NZ 3.39Å; E535-F560 WeakPolarHBondContact O-CA 3.45Å; E535-E561 WeakPolarHBondContact CB-O 3.38Å; E535-E561 PolarHBondContact N-O 3.43Å; E535-E561 PolarHBondContact O-N 2.93Å
536S91.6Very high93.3Very high37 Ų3751.9 Ų51.926%0.25926%0.256SS..EExtended strand (participates in β ladder)trans-67.4130.4176.4-175.90000111.9F528 Y534 G538F528-S536 WeakPolarHBondContact CZ-OG 3.34Å; Y534-S536 PolarHBondContact O-N 3.47Å; S536-G538 VanDerWaalsContact C-N 3.33Å; S536-G538 PolarHBondContact OG-N 3.06Å
537K94.1Very high93.5Very high49 Ų4951.7 Ų51.721%0.21325%0.252CS..EExtended strand (participates in β ladder)trans-99.323.7172.6-53.5-59176.3177.90112.2T483 E535 K540 V559 E561T483-K537 WeakPolarHBondContact CG2-O 3.46Å; E535-K537 PolarHBondContact O-N 2.83Å; E535-K537 IonicContact OE1-NZ 2.73Å; E535-K537 PolarHBondContact OE1-NZ 3.42Å; E535-K537 IonicContact OE2-NZ 2.65Å; E535-K537 PolarHBondContact OE2-NZ 3.39Å; K537-K540 WeakPolarHBondContact O-CE 3.33Å; K537-V559 HydrophobicContact CB-CB 4.21Å; K537-V559 HydrophobicContact CB-CG1 4.02Å; K537-V559 HydrophobicContact CG-CG1 4.41Å; K537-V559 PolarHBondContact N-O 2.97Å; K537-E561 VanDerWaalsContact CE-CD 3.49Å; K537-E561 WeakPolarHBondContact CE-OE2 3.35Å; K537-E561 HydrophobicContact CG-CB 4.35Å; K537-E561 HydrophobicContact CG-CG 3.92Å; K537-E561 IonicContact NZ-OE2 3.39Å
538G93.7Very high93.7Very high4 Ų451.8 Ų51.84%0.04125%0.253CS..EExtended strand (participates in β ladder)trans77.7169.1177.200000114.4F484 S536 V559F484-G538 WeakPolarHBondContact O-CA 3.4Å; S536-G538 VanDerWaalsContact C-N 3.33Å; S536-G538 PolarHBondContact OG-N 3.06Å; G538-V559 PolarHBondContact O-N 3.24Å
539I96.3Very high94Very high0 Ų049.3 Ų49.30%024%0.244CC..EExtended strand (participates in β ladder)trans-86.7132.1175.7-48.7-54.3000108.6T483 F484 F491 L521 V524 F528 V556 E557 S558T483-I539 CarbonylContact C-O 3.59Å; T483-I539 WeakPolarHBondContact CA-O 3.46Å; F484-I539 HydrophobicContact CB-CB 4.42Å; F484-I539 PolarHBondContact N-O 2.9Å; F484-I539 PolarHBondContact O-N 3.13Å; F491-I539 HydrophobicContact CE1-CB 4.43Å; F491-I539 HydrophobicContact CE1-CG1 4.2Å; L521-I539 HydrophobicContact CD1-CG2 4.13Å; V524-I539 HydrophobicContact CG1-CD1 3.89Å; V524-I539 HydrophobicContact CG1-CG1 4.06Å; F528-I539 HydrophobicContact CE2-CD1 4.27Å; I539-V556 HydrophobicContact CG2-CG1 3.46Å; I539-V556 VanDerWaalsContact CG2-CG1 3.46Å; I539-E557 CarbonylContact C-O 3.55Å; I539-S558 WeakPolarHBondContact CD1-OG 3.47Å
540K96.9Very high94.3Very high38 Ų3843 Ų4317%0.16522%0.218CC..EExtended strand (participates in β ladder)trans-119.8112.8-172-64.6179.6-167.9175.80110.6V481 I482 T483 K537 H542 V556 E557 V559V481-K540 HydrophobicContact CG1-CB 3.85Å; V481-K540 HydrophobicContact CG1-CG 4.35Å; I482-K540 WeakPolarHBondContact O-CA 3.31Å; T483-K540 HydrophobicContact CG2-CG 3.96Å; K537-K540 WeakPolarHBondContact O-CE 3.33Å; K540-H542 PolarHBondContact O-CD2 3.29Å; K540-V556 CarbonylContact O-C 3.59Å; K540-V556 WeakPolarHBondContact O-CA 3.23Å; K540-E557 HydrophobicContact CB-CG 3.87Å; K540-E557 PolarHBondContact N-O 3.42Å; K540-E557 PolarHBondContact O-N 3Å; K540-V559 HydrophobicContact CD-CG2 3.82Å; K540-V559 HydrophobicContact CG-CG2 4.46Å
541A97.8Very high94.6Very high0 Ų039.3 Ų39.30%020%0.203CC..EExtended strand (participates in β ladder)trans-91126.9171.400000110V481 I482 F484 F493 F543 L553 V556V481-A541 VanDerWaalsContact CA-O 3.31Å; V481-A541 WeakPolarHBondContact CA-O 3.26Å; I482-A541 PolarHBondContact N-O 2.89Å; I482-A541 PolarHBondContact O-N 3.35Å; F484-A541 HydrophobicContact CE2-CB 3.84Å; F493-A541 HydrophobicContact CE1-CB 4.33Å; F493-A541 HydrophobicContact CZ-CB 3.95Å; A541-F543 HydrophobicContact CB-CD2 4.38Å; A541-F543 HydrophobicContact CB-CE2 3.51Å; A541-F543 HydrophobicContact CB-CZ 3.7Å; A541-L553 HydrophobicContact CB-CD1 3.82Å; A541-V556 HydrophobicContact CB-CG2 4.05Å
542H97.8Very high95Very high50 Ų5039.5 Ų39.523%0.23121%0.21CC..EExtended strand (participates in β ladder)trans-102.3106.2-178.1-68.1-101.5000110.3V481 K540 L553 D554 R555 E557V481-H542 WeakPolarHBondContact CG2-CE1 3.24Å; V481-H542 WeakPolarHBondContact CG2-ND1 3.48Å; K540-H542 PolarHBondContact O-CD2 3.29Å; H542-L553 CarbonylContact O-C 3.54Å; H542-D554 HydrophobicContact CB-CB 4.44Å; H542-D554 PolarHBondContact O-N 3.03Å; H542-R555 HydrophobicContact CB-CG 4.29Å; H542-R555 PolarHBondContact N-O 3.34Å; H542-R555 PolarHBondContact NE2-NH2 3.46Å; H542-E557 IonicContact CD2-OE2 2.72Å; H542-E557 IonicContact NE2-OE2 2.96Å
543F98.1Very high95.5Very high1 Ų136.5 Ų36.50%0.00419%0.189CC..EExtended strand (participates in β ladder)trans-99.8141.7178.9-55.4-89.8000110.8V447 L469 F470 R479 K480 I482 F493 I495 A541 L551 S552 L553V447-F543 HydrophobicContact CG2-CE1 4.2Å; V447-F543 HydrophobicContact CG2-CE2 4.23Å; V447-F543 HydrophobicContact CG2-CZ 3.73Å; L469-F543 HydrophobicContact CD1-CB 4.14Å; L469-F543 HydrophobicContact CD1-CD1 3.67Å; L469-F543 HydrophobicContact CD1-CD2 3.94Å; L469-F543 HydrophobicContact CD1-CE1 3.98Å; L469-F543 HydrophobicContact CD1-CE2 4.23Å; L469-F543 HydrophobicContact CD1-CG 3.63Å; L469-F543 HydrophobicContact CD1-CZ 4.25Å; L469-F543 HydrophobicContact CD2-CB 4.43Å; L469-F543 HydrophobicContact CD2-CD2 3.54Å; L469-F543 HydrophobicContact CD2-CE2 3.91Å; L469-F543 HydrophobicContact CD2-CG 4.01Å; L469-F543 HydrophobicContact CG-CD2 4.42Å; F470-F543 HydrophobicContact CE2-CB 4.36Å; F470-F543 HydrophobicContact CZ-CB 4.3Å; R479-F543 CarbonylContact C-O 3.47Å; R479-F543 WeakPolarHBondContact CA-O 3.42Å; K480-F543 PolarHBondContact N-O 2.91Å; K480-F543 PolarHBondContact O-N 2.93Å; I482-F543 HydrophobicContact CB-CE2 4.04Å; I482-F543 HydrophobicContact CG1-CD2 4.29Å; I482-F543 HydrophobicContact CG1-CE2 3.83Å; F493-F543 HydrophobicContact CE2-CE1 4.12Å; F493-F543 AromaticContact CE2-CZ 3.68Å; F493-F543 HydrophobicContact CE2-CZ 3.68Å; F493-F543 HydrophobicContact CZ-CE1 4.44Å; F493-F543 AromaticContact CZ-CZ 3.88Å; F493-F543 HydrophobicContact CZ-CZ 3.88Å; I495-F543 HydrophobicContact CD1-CD1 4.41Å; I495-F543 HydrophobicContact CD1-CE1 3.77Å; I495-F543 HydrophobicContact CG1-CE1 4.24Å; A541-F543 HydrophobicContact CB-CD2 4.38Å; A541-F543 HydrophobicContact CB-CE2 3.51Å; A541-F543 HydrophobicContact CB-CZ 3.7Å; F543-L551 HydrophobicContact CB-CD1 4.49Å; F543-S552 WeakPolarHBondContact CA-O 3.47Å; F543-L553 HydrophobicContact CD1-CB 4.35Å; F543-L553 HydrophobicContact CD1-CD1 4.03Å; F543-L553 HydrophobicContact CE1-CB 4.41Å; F543-L553 HydrophobicContact CE1-CD1 3.85Å; F543-L553 HydrophobicContact CG-CD1 4.47Å; F543-L553 HydrophobicContact CZ-CD1 4.13Å
544N97.8Very high95.9Very high18 Ų1833.4 Ų33.410%0.09617%0.172CC..EExtended strand (participates in β ladder)trans-128.4130.6173.8173.890.3000108.5R479 S552 D554R479-N544 HydrophobicContact CG-CB 3.95Å; R479-N544 WeakPolarHBondContact CG-OD1 3.48Å; R479-N544 PolarHBondContact NE-OD1 3.48Å; N544-S552 WeakPolarHBondContact CB-OG 3.48Å; N544-S552 PolarHBondContact N-O 2.74Å; N544-S552 PolarHBondContact O-N 3.21Å; N544-S552 PolarHBondContact O-OG 2.71Å; N544-D554 WeakPolarHBondContact CB-OD1 3.16Å; N544-D554 WeakPolarHBondContact CB-OD2 3.04Å
545L97.7Very high96.2Very high4 Ų435.6 Ų35.62%0.02118%0.18CC..EExtended strand (participates in β ladder)trans-106.5108.8165-168.973.6000105.6V441 I445 F470 Y476 P477 Q478 G549 L551V441-L545 HydrophobicContact CG2-CD2 3.41Å; V441-L545 VanDerWaalsContact CG2-CD2 3.41Å; I445-L545 HydrophobicContact CD1-CD1 4.39Å; F470-L545 HydrophobicContact CB-CD2 4.33Å; F470-L545 HydrophobicContact CD1-CB 4.2Å; F470-L545 HydrophobicContact CD1-CD2 4.27Å; F470-L545 HydrophobicContact CD2-CB 4.22Å; F470-L545 HydrophobicContact CD2-CD2 4.37Å; F470-L545 HydrophobicContact CE1-CB 3.93Å; F470-L545 HydrophobicContact CE2-CB 3.95Å; F470-L545 HydrophobicContact CG-CB 4.36Å; F470-L545 HydrophobicContact CG-CD2 4.04Å; F470-L545 HydrophobicContact CZ-CB 3.8Å; Y476-L545 HydrophobicContact CG-CD2 4.28Å; P477-L545 CarbonylContact C-O 3.58Å; P477-L545 VanDerWaalsContact CA-O 3.25Å; P477-L545 WeakPolarHBondContact CA-O 3.2Å; P477-L545 WeakPolarHBondContact CB-O 3.34Å; Q478-L545 PolarHBondContact N-O 3.18Å; Q478-L545 PolarHBondContact O-N 3.36Å; L545-G549 WeakPolarHBondContact CD1-O 3.47Å; L545-L551 HydrophobicContact CD1-CB 4.29Å
546D96.9Very high96.5Very high39 Ų3929.9 Ų29.921%0.20915%0.153CC..  trans-75.9-178.3-168.281.1-18.7000113.1Y476 S548 G549 V550Y476-D546 VanDerWaalsContact CD2-O 3.29Å; Y476-D546 WeakPolarHBondContact CD2-O 3.21Å; D546-S548 VanDerWaalsContact CG-N 3.33Å; D546-S548 PolarHBondContact O-N 3.04Å; D546-S548 VanDerWaalsContact OD1-CA 3.26Å; D546-S548 WeakPolarHBondContact OD1-CA 3.5Å; D546-S548 VanDerWaalsContact OD1-CB 3.23Å; D546-S548 WeakPolarHBondContact OD1-CB 3.39Å; D546-S548 PolarHBondContact OD1-N 3Å; D546-S548 WeakPolarHBondContact OD2-CB 3.36Å; D546-S548 PolarHBondContact OD2-OG 3.39Å; D546-G549 PolarHBondContact O-N 2.84Å; D546-G549 VanDerWaalsContact O-N 3.07Å; D546-G549 PolarHBondContact OD1-N 2.77Å; D546-V550 PolarHBondContact N-O 2.92Å; D546-V550 VanDerWaalsContact N-O 3.07Å; D546-V550 WeakPolarHBondContact OD1-CA 3.33Å; D546-V550 PolarHBondContact OD1-N 3.22Å
547E95.8Very high96.8Very high86 Ų8628.5 Ų28.540%0.40214%0.143SC..THydrogen-bonded Turntrans-58.5-25.6174.5-70.570.6-161.700112.6Q201 P477 G549Q201-E547 HydrophobicContact CG-CB 3.96Å; Q201-E547 WeakPolarHBondContact CG-O 3.49Å; Q201-E547 PolarHBondContact NE2-O 3.42Å; P477-E547 HydrophobicContact CG-CG 4.14Å; E547-G549 VanDerWaalsContact C-N 3.33Å
548S97.9Very high96.8Very high6 Ų626.2 Ų26.24%0.04213%0.133CC..THydrogen-bonded Turntrans-82.9-7.5177.6-51.30000113.8R185 L202 D546 V550R185-S548 PolarHBondContact NH1-O 3.49Å; L202-S548 PolarHBondContact N-OG 3.02Å; L202-S548 VanDerWaalsContact N-OG 3.1Å; L202-S548 WeakPolarHBondContact O-CA 3.45Å; D546-S548 VanDerWaalsContact CG-N 3.33Å; D546-S548 PolarHBondContact O-N 3.04Å; D546-S548 VanDerWaalsContact OD1-CA 3.26Å; D546-S548 WeakPolarHBondContact OD1-CA 3.5Å; D546-S548 VanDerWaalsContact OD1-CB 3.23Å; D546-S548 WeakPolarHBondContact OD1-CB 3.39Å; D546-S548 PolarHBondContact OD1-N 3Å; D546-S548 WeakPolarHBondContact OD2-CB 3.36Å; D546-S548 PolarHBondContact OD2-OG 3.39Å; S548-V550 VanDerWaalsContact C-N 3.31Å
549G97.3Very high96.9Very high6 Ų626 Ų266%0.06213%0.131CC..SBendtrans73.921.8-17100000113.2Q182 Y476 L545 D546 E547Q182-G549 PolarHBondContact NE2-O 3.06Å; Y476-G549 VanDerWaalsContact CE2-CA 3.47Å; Y476-G549 VanDerWaalsContact CE2-N 3.34Å; L545-G549 WeakPolarHBondContact CD1-O 3.47Å; D546-G549 PolarHBondContact O-N 2.84Å; D546-G549 VanDerWaalsContact O-N 3.07Å; D546-G549 PolarHBondContact OD1-N 2.77Å; E547-G549 VanDerWaalsContact C-N 3.33Å
550V97.4Very high96.7Very high20 Ų2026 Ų2612%0.12113%0.131CC..  trans-99.4137.1180179.80000110.1R185 L189 D546 S548R185-V550 HydrophobicContact CB-CG2 3.95Å; L189-V550 HydrophobicContact CD1-CG2 4.21Å; D546-V550 PolarHBondContact N-O 2.92Å; D546-V550 VanDerWaalsContact N-O 3.07Å; D546-V550 WeakPolarHBondContact OD1-CA 3.33Å; D546-V550 PolarHBondContact OD1-N 3.22Å; S548-V550 VanDerWaalsContact C-N 3.31Å
551L97.5Very high96.5Very high33 Ų3326.2 Ų26.217%0.17313%0.133CC..EExtended strand (participates in β ladder)trans-87.9127.6-176.8-179.170.9000112.1I445 F470 I495 L516 F543 L545I445-L551 HydrophobicContact CD1-CB 4.45Å; I445-L551 HydrophobicContact CD1-CD2 4.35Å; I445-L551 HydrophobicContact CG2-CD2 4.11Å; F470-L551 HydrophobicContact CD2-CD1 4.24Å; F470-L551 HydrophobicContact CE2-CD1 3.59Å; I495-L551 HydrophobicContact CD1-CD2 4.31Å; I495-L551 HydrophobicContact CG2-CD2 3.65Å; L516-L551 HydrophobicContact CD1-CD2 4.31Å; F543-L551 HydrophobicContact CB-CD1 4.49Å; L545-L551 HydrophobicContact CD1-CB 4.29Å
552S96.3Very high96.1Very high43 Ų4328.2 Ų28.230%0.30115%0.145SC..EExtended strand (participates in β ladder)trans-117.8148.8163.157.90000112.2F543 N544 D554F543-S552 WeakPolarHBondContact CA-O 3.47Å; N544-S552 WeakPolarHBondContact CB-OG 3.48Å; N544-S552 PolarHBondContact N-O 2.74Å; N544-S552 PolarHBondContact O-N 3.21Å; N544-S552 PolarHBondContact O-OG 2.71Å; S552-D554 WeakPolarHBondContact CB-OD1 3.36Å; S552-D554 PolarHBondContact OG-OD1 2.91Å
553L97Very high95.5Very high31 Ų3131.4 Ų31.416%0.16216%0.163CC..EExtended strand (participates in β ladder)trans-100.999158.8172.759000106.6F493 V519 A541 H542 F543 R555 V556 V639 L641F493-L553 HydrophobicContact CZ-CD2 4.16Å; V519-L553 HydrophobicContact CG1-CD2 3.69Å; V519-L553 HydrophobicContact CG2-CD2 3.99Å; A541-L553 HydrophobicContact CB-CD1 3.82Å; H542-L553 CarbonylContact O-C 3.54Å; F543-L553 HydrophobicContact CD1-CB 4.35Å; F543-L553 HydrophobicContact CD1-CD1 4.03Å; F543-L553 HydrophobicContact CE1-CB 4.41Å; F543-L553 HydrophobicContact CE1-CD1 3.85Å; F543-L553 HydrophobicContact CG-CD1 4.47Å; F543-L553 HydrophobicContact CZ-CD1 4.13Å; L553-R555 PolarHBondContact O-N 2.98Å; L553-V556 HydrophobicContact CD1-CG2 4.01Å; L553-V556 HydrophobicContact CD2-CG2 3.94Å; L553-V556 HydrophobicContact CG-CG2 4.26Å; L553-V639 HydrophobicContact CD2-CG1 4.2Å; L553-L641 HydrophobicContact CD2-CD2 4.17Å
554D95.9Very high94.5Very high68 Ų6833.9 Ų33.936%0.36418%0.178SC..EExtended strand (participates in β ladder)trans-67.7-37.9-169-63.7-5.8000112.3H542 N544 S552H542-D554 HydrophobicContact CB-CB 4.44Å; H542-D554 PolarHBondContact O-N 3.03Å; N544-D554 WeakPolarHBondContact CB-OD1 3.16Å; N544-D554 WeakPolarHBondContact CB-OD2 3.04Å; S552-D554 WeakPolarHBondContact CB-OD1 3.36Å; S552-D554 PolarHBondContact OG-OD1 2.91Å
555R95.5Very high92.5Very high93 Ų9341 Ų4135%0.35121%0.211SC..EExtended strand (participates in β ladder)trans-169.7171.3171.465.7176.9-175.1-75.5-4.3111.6H542 L553 E557 E636H542-R555 HydrophobicContact CB-CG 4.29Å; H542-R555 PolarHBondContact N-O 3.34Å; H542-R555 PolarHBondContact NE2-NH2 3.46Å; L553-R555 PolarHBondContact O-N 2.98Å; R555-E557 IonicContact CZ-OE2 2.79Å; R555-E557 VanDerWaalsContact CZ-OE2 3.3Å; R555-E557 IonicContact NE-OE2 2.66Å; R555-E557 PolarHBondContact NE-OE2 3.44Å; R555-E557 IonicContact NH2-OE2 2.65Å; R555-E557 PolarHBondContact NH2-OE2 2.9Å; R555-E636 WeakPolarHBondContact CB-OE1 3.34Å
556V97.7Very high90.2Very high1 Ų146.7 Ų46.71%0.00624%0.241CC..EExtended strand (participates in β ladder)trans-126.2127.3166.7-176.90000109.3L521 I539 K540 A541 L553 I637 V639L521-V556 HydrophobicContact CD1-CG1 4.04Å; L521-V556 HydrophobicContact CD2-CB 4.19Å; L521-V556 HydrophobicContact CD2-CG1 4.01Å; L521-V556 HydrophobicContact CD2-CG2 3.89Å; I539-V556 HydrophobicContact CG2-CG1 3.46Å; I539-V556 VanDerWaalsContact CG2-CG1 3.46Å; K540-V556 CarbonylContact O-C 3.59Å; K540-V556 WeakPolarHBondContact O-CA 3.23Å; A541-V556 HydrophobicContact CB-CG2 4.05Å; L553-V556 HydrophobicContact CD1-CG2 4.01Å; L553-V556 HydrophobicContact CD2-CG2 3.94Å; L553-V556 HydrophobicContact CG-CG2 4.26Å; V556-I637 HydrophobicContact CB-CB 4.32Å; V556-I637 HydrophobicContact CG1-CB 4.11Å; V556-I637 HydrophobicContact CG1-CG2 4.38Å; V556-I637 PolarHBondContact O-N 3.36Å; V556-V639 HydrophobicContact CB-CG2 3.94Å; V556-V639 HydrophobicContact CG2-CG2 3.66Å
557E96.8Very high87.4Confident9 Ų950 Ų504%0.04227%0.267CS..EExtended strand (participates in β ladder)trans-122.5134.7-177.967.2179.9-12300112.5I539 K540 H542 R555 V559 R632 V634 E635I539-E557 CarbonylContact C-O 3.55Å; K540-E557 HydrophobicContact CB-CG 3.87Å; K540-E557 PolarHBondContact N-O 3.42Å; K540-E557 PolarHBondContact O-N 3Å; H542-E557 IonicContact CD2-OE2 2.72Å; H542-E557 IonicContact NE2-OE2 2.96Å; R555-E557 IonicContact CZ-OE2 2.79Å; R555-E557 VanDerWaalsContact CZ-OE2 3.3Å; R555-E557 IonicContact NE-OE2 2.66Å; R555-E557 PolarHBondContact NE-OE2 3.44Å; R555-E557 IonicContact NH2-OE2 2.65Å; R555-E557 PolarHBondContact NH2-OE2 2.9Å; E557-V559 HydrophobicContact CG-CG2 4Å; E557-V559 WeakPolarHBondContact OE1-CG2 3.45Å; E557-R632 IonicContact OE1-NH2 2.97Å; E557-R632 PolarHBondContact OE1-NH2 2.73Å; E557-V634 HydrophobicContact CB-CG1 3.67Å; E557-V634 HydrophobicContact CG-CG1 4.08Å; E557-E635 CarbonylContact C-O 3.39Å; E557-E635 VanDerWaalsContact CA-O 3.25Å; E557-E635 WeakPolarHBondContact CA-O 3.39Å
558S95.8Very high84.9Confident0 Ų050.5 Ų50.50%029%0.286CS..EExtended strand (participates in β ladder)trans-89.6127.6167.8-170.90000108.8S527 I539 F560 V634 E635S527-S558 WeakPolarHBondContact OG-CB 3.33Å; S527-S558 PolarHBondContact OG-OG 2.86Å; I539-S558 WeakPolarHBondContact CD1-OG 3.47Å; S558-F560 WeakPolarHBondContact OG-CE2 2.78Å; S558-F560 WeakPolarHBondContact OG-CZ 3.44Å; S558-V634 WeakPolarHBondContact O-CA 3.32Å; S558-E635 PolarHBondContact N-O 3.45Å; S558-E635 PolarHBondContact O-N 2.96Å
559V94.5Very high82.1Confident0 Ų059.1 Ų59.10%033%0.326CS..EExtended strand (participates in β ladder)trans-117.9133.5-174.3-177.70000111.1K537 G538 K540 E557 R632 V634K537-V559 HydrophobicContact CB-CB 4.21Å; K537-V559 HydrophobicContact CB-CG1 4.02Å; K537-V559 HydrophobicContact CG-CG1 4.41Å; K537-V559 PolarHBondContact N-O 2.97Å; G538-V559 PolarHBondContact O-N 3.24Å; K540-V559 HydrophobicContact CD-CG2 3.82Å; K540-V559 HydrophobicContact CG-CG2 4.46Å; E557-V559 HydrophobicContact CG-CG2 4Å; E557-V559 WeakPolarHBondContact OE1-CG2 3.45Å; V559-R632 HydrophobicContact CG1-CG 3.97Å; V559-R632 VanDerWaalsContact CG1-NE 3.29Å; V559-V634 HydrophobicContact CG2-CG1 4.39Å; V559-V634 HydrophobicContact CG2-CG2 4.35Å
560F93Very high79.4Confident0 Ų067.8 Ų67.80%037%0.365CS..EExtended strand (participates in β ladder)trans-129.9146.5177.9-58.3-91.6000110.7S527 F528 Y531 Y534 E535 S558 R632 M633S527-F560 WeakPolarHBondContact O-CZ 3.17Å; F528-F560 HydrophobicContact CB-CZ 4.46Å; F528-F560 AromaticContact CD1-CE1 3.78Å; F528-F560 HydrophobicContact CD1-CE1 3.78Å; F528-F560 HydrophobicContact CD1-CZ 4.24Å; F528-F560 HydrophobicContact CD2-CE1 4.22Å; F528-F560 AromaticContact CD2-CZ 3.85Å; F528-F560 HydrophobicContact CD2-CZ 3.85Å; F528-F560 AromaticContact CE1-CE1 3.95Å; F528-F560 HydrophobicContact CE1-CE1 3.95Å; F528-F560 HydrophobicContact CE1-CZ 4.48Å; F528-F560 HydrophobicContact CE2-CE1 4.36Å; F528-F560 HydrophobicContact CE2-CZ 4.11Å; F528-F560 AromaticContact CG-CE1 3.94Å; F528-F560 HydrophobicContact CG-CE1 3.94Å; F528-F560 AromaticContact CG-CZ 3.92Å; F528-F560 HydrophobicContact CG-CZ 3.92Å; F528-F560 HydrophobicContact CZ-CE1 4.24Å; F528-F560 HydrophobicContact CZ-CZ 4.42Å; Y531-F560 AromaticContact CD2-CD2 3.88Å; Y531-F560 HydrophobicContact CD2-CD2 3.88Å; Y531-F560 HydrophobicContact CD2-CE2 4.12Å; Y531-F560 HydrophobicContact CD2-CG 4.46Å; Y531-F560 HydrophobicContact CG-CD2 4.39Å; Y534-F560 HydrophobicContact CD1-CB 4.29Å; Y534-F560 HydrophobicContact CG-CB 4.35Å; E535-F560 WeakPolarHBondContact O-CA 3.45Å; S558-F560 WeakPolarHBondContact OG-CE2 2.78Å; S558-F560 WeakPolarHBondContact OG-CZ 3.44Å; F560-R632 CarbonylContact O-C 3.58Å; F560-R632 WeakPolarHBondContact O-CA 3.47Å; F560-M633 HydrophobicContact CB-CB 4.38Å; F560-M633 PolarHBondContact N-O 2.86Å; F560-M633 PolarHBondContact O-N 3.16Å
561E92.6Very high76.5Confident43 Ų4373.6 Ų73.620%0.20139%0.391CS..EExtended strand (participates in β ladder)trans-129.3141173-72.2178.4-161.600110.7E535 K537 K630 R631 R632E535-E561 WeakPolarHBondContact CB-O 3.38Å; E535-E561 PolarHBondContact N-O 3.43Å; E535-E561 PolarHBondContact O-N 2.93Å; K537-E561 VanDerWaalsContact CE-CD 3.49Å; K537-E561 WeakPolarHBondContact CE-OE2 3.35Å; K537-E561 HydrophobicContact CG-CB 4.35Å; K537-E561 HydrophobicContact CG-CG 3.92Å; K537-E561 IonicContact NZ-OE2 3.39Å; E561-K630 IonicContact OE2-NZ 3.42Å; E561-K630 PolarHBondContact OE2-NZ 3.5Å; E561-R631 WeakPolarHBondContact CA-O 3.36Å; E561-R632 HydrophobicContact CG-CB 4.27Å; E561-R632 HydrophobicContact CG-CG 4.37Å
562T89.2Confident74.1Confident41 Ų4175.4 Ų75.425%0.25241%0.406SS..EExtended strand (participates in β ladder)trans-132.8162.8164.3-157.20000111D533 Y534 K630 R631D533-T562 PolarHBondContact O-OG1 2.75Å; Y534-T562 HydrophobicContact CD1-CG2 3.67Å; Y534-T562 HydrophobicContact CD2-CG2 4.39Å; Y534-T562 HydrophobicContact CE1-CG2 3.36Å; Y534-T562 HydrophobicContact CE2-CG2 4.13Å; Y534-T562 HydrophobicContact CG-CG2 4.16Å; T562-K630 WeakPolarHBondContact O-CA 3.32Å; T562-R631 HydrophobicContact CG2-CB 4.43Å; T562-R631 PolarHBondContact N-O 2.78Å; T562-R631 PolarHBondContact O-N 3.34Å
563L84.4Confident71.7Confident118 Ų11878.6 Ų78.662%0.61842%0.424SS*.EExtended strand (participates in β ladder)trans-87.9132.1173.8-64.4175000109A628 K630L563-A628 HydrophobicContact CD2-CB 4.37Å; L563-K630 HydrophobicContact CD2-CG 3.97Å
564V77.3Confident69.4Low53 Ų5383.3 Ų83.332%0.32145%0.449SS..EExtended strand (participates in β ladder)trans-108.3124170.7-178.80000108.2R629 R631V564-R629 WeakPolarHBondContact CB-O 3.39Å; V564-R629 PolarHBondContact N-O 3.13Å; V564-R629 PolarHBondContact O-N 2.97Å; V564-R631 HydrophobicContact CG2-CB 3.66Å
565E57Low67.3Low168 Ų16883.7 Ų83.779%0.78545%0.453SS*.  trans-81.1140.2163.2-60.7-166.2142.700108.8S567E565-S567 VanDerWaalsContact C-N 3.25Å; E565-S567 PolarHBondContact O-N 3.08Å
566D47.7Very low64.8Low123 Ų12385.1 Ų85.166%0.65846%0.462SS*.  trans-7471.6-175.9-72.7-35.3000111.8A568D566-A568 PolarHBondContact O-N 3.34Å
567S39.1Very low62.4Low107 Ų10790.4 Ų90.475%0.74849%0.49SS*.  trans-74112.3163.361.40000109.4E565 E569E565-S567 VanDerWaalsContact C-N 3.25Å; E565-S567 PolarHBondContact O-N 3.08Å; S567-E569 PolarHBondContact O-N 3.27Å; S567-E569 VanDerWaalsContact O-N 3.08Å
568A42.6Very low60.1Low98 Ų9891.8 Ų91.881%0.8151%0.506SS*.  trans-81.586.3-172.200000113.1D566D566-A568 PolarHBondContact O-N 3.34Å
569E40.2Very low57.8Low186 Ų18697.1 Ų97.187%0.86954%0.535SS*.  trans-157.6149.4154-115.1152.3-149.100112.9S567S567-E569 PolarHBondContact O-N 3.27Å; S567-E569 VanDerWaalsContact O-N 3.08Å
570E40Very low55.4Low189 Ų189101.1 Ų101.188%0.88356%0.559SS**  trans51.386.2173-54-154.6151.800120.2S572E570-S572 PolarHBondContact O-N 3.22Å
571E36.8Very low53.3Low141 Ų141105.9 Ų105.966%0.65958%0.584SS**  trans-64.293.4157.1-84.3-157.1141.900111.5T573 K576E571-T573 PolarHBondContact O-N 3.16Å; E571-K576 VanDerWaalsContact OE2-CE 3.24Å; E571-K576 WeakPolarHBondContact OE2-CE 3.44Å; E571-K576 IonicContact OE2-NZ 3.95Å; E571-K576 PolarHBondContact OE2-NZ 3.42Å
572S46.7Very low50.9Low71 Ų71108.5 Ų108.550%0.49761%0.607SS.*  trans-60.5136.4169.3-175.60000111.8E570 L574 T575E570-S572 PolarHBondContact O-N 3.22Å; S572-L574 PolarHBondContact O-N 3.01Å; S572-L574 VanDerWaalsContact O-N 3.13Å; S572-T575 WeakPolarHBondContact O-CB 3.35Å; S572-T575 PolarHBondContact O-N 3.37Å; S572-T575 PolarHBondContact O-OG1 2.82Å
573T45.9Very low48.6Very low110 Ų110110.4 Ų110.468%0.67562%0.622SS**THydrogen-bonded Turntrans-60-25.7-172.149.70000114.4E571 T575 K576E571-T573 PolarHBondContact O-N 3.16Å; T573-T575 PolarHBondContact O-N 3.31Å; T573-K576 PolarHBondContact O-N 2.92Å
574L49.8Very low46.5Very low131 Ų131111.3 Ų111.369%0.68663%0.627SS**Hα-helixtrans-56-32.9174-76.8163.3000112.9S572 K576 L577 G578S572-L574 PolarHBondContact O-N 3.01Å; S572-L574 VanDerWaalsContact O-N 3.13Å; L574-K576 PolarHBondContact O-N 2.88Å; L574-L577 PolarHBondContact O-N 3.48Å; L574-L577 VanDerWaalsContact O-N 3.11Å; L574-G578 PolarHBondContact O-N 2.9Å
575T51.4Low45Very low75 Ų75117.5 Ų117.546%0.4665%0.649SS.*Hα-helixtrans-62.1-24.3178.8-35.70000112.3S572 T573 N579S572-T575 WeakPolarHBondContact O-CB 3.35Å; S572-T575 PolarHBondContact O-N 3.37Å; S572-T575 PolarHBondContact O-OG1 2.82Å; T573-T575 PolarHBondContact O-N 3.31Å; T575-N579 PolarHBondContact O-ND2 3.09Å
576K43.4Very low44Very low123 Ų123112.6 Ų112.654%0.53564%0.644SS.*Hα-helixtrans-81.7-26.8177.4-74.8166.8-179.91520112.8E571 T573 L574 T580E571-K576 VanDerWaalsContact OE2-CE 3.24Å; E571-K576 WeakPolarHBondContact OE2-CE 3.44Å; E571-K576 IonicContact OE2-NZ 3.95Å; E571-K576 PolarHBondContact OE2-NZ 3.42Å; T573-K576 PolarHBondContact O-N 2.92Å; L574-K576 PolarHBondContact O-N 2.88Å; K576-T580 PolarHBondContact O-OG1 3.46Å
577L47.1Very low43.2Very low113 Ų113110.7 Ų110.759%0.59265%0.653SS**Hα-helixtrans-73.2-42.9174.2-88.885.3000113L574 N579 T580 I581L574-L577 PolarHBondContact O-N 3.48Å; L574-L577 VanDerWaalsContact O-N 3.11Å; L577-N579 VanDerWaalsContact C-N 3.25Å; L577-N579 PolarHBondContact O-N 3.15Å; L577-T580 PolarHBondContact O-N 3.18Å; L577-T580 VanDerWaalsContact O-N 3.13Å; L577-I581 PolarHBondContact O-N 3.44Å
578G48.4Very low42.7Very low37 Ų37109.1 Ų109.138%0.38166%0.655SS.*Hα-helixtrans-60.9-33.8-176.800000113.6L574 S582L574-G578 PolarHBondContact O-N 2.9Å; G578-S582 PolarHBondContact O-N 3.07Å; G578-S582 PolarHBondContact O-OG 3.29Å
579N45.9Very low42.1Very low112 Ų112111 Ų11160%0.59966%0.656SS**Hα-helixtrans-71.7-34.9176.9-71.1-31.4000112.5T575 L577 S582 S583T575-N579 PolarHBondContact O-ND2 3.09Å; L577-N579 VanDerWaalsContact C-N 3.25Å; L577-N579 PolarHBondContact O-N 3.15Å; N579-S582 PolarHBondContact O-N 3Å; N579-S583 PolarHBondContact O-N 2.92Å
580T44.9Very low41.6Very low84 Ų84108.5 Ų108.552%0.51565%0.653SS.*Hα-helixtrans-71.3-33.5177.4-320000112.5K576 L577 S582 S583 L584K576-T580 PolarHBondContact O-OG1 3.46Å; L577-T580 PolarHBondContact O-N 3.18Å; L577-T580 VanDerWaalsContact O-N 3.13Å; T580-S582 VanDerWaalsContact C-N 3.32Å; T580-S583 PolarHBondContact O-N 3.36Å; T580-S583 PolarHBondContact O-OG 3.41Å; T580-S583 VanDerWaalsContact O-OG 3.05Å; T580-L584 PolarHBondContact O-N 3.46Å
581I48.4Very low41.7Very low101 Ų101104.8 Ų104.852%0.51865%0.646SS.*Hα-helixtrans-68.1-36.9173.9-63.3169000110.2L577 S583 L584 F585L577-I581 PolarHBondContact O-N 3.44Å; I581-S583 VanDerWaalsContact C-N 3.27Å; I581-S583 PolarHBondContact O-N 3Å; I581-L584 PolarHBondContact O-N 2.92Å; I581-L584 VanDerWaalsContact O-N 3.16Å; I581-F585 HydrophobicContact CG2-CD2 4.5Å; I581-F585 HydrophobicContact CG2-CE2 4.16Å
582S41.5Very low41.3Very low97 Ų97106.1 Ų106.168%0.67866%0.657SS**Hα-helixtrans-65-26.5179.3-59.10000113.8G578 N579 T580G578-S582 PolarHBondContact O-N 3.07Å; G578-S582 PolarHBondContact O-OG 3.29Å; N579-S582 PolarHBondContact O-N 3Å; T580-S582 VanDerWaalsContact C-N 3.32Å
583S41.6Very low40.4Very low82 Ų82106.9 Ų106.957%0.57367%0.668SS**Hα-helixtrans-88.6-19.7173.353.70000114N579 T580 I581 F585 G586N579-S583 PolarHBondContact O-N 2.92Å; T580-S583 PolarHBondContact O-N 3.36Å; T580-S583 PolarHBondContact O-OG 3.41Å; T580-S583 VanDerWaalsContact O-OG 3.05Å; I581-S583 VanDerWaalsContact C-N 3.27Å; I581-S583 PolarHBondContact O-N 3Å; S583-F585 VanDerWaalsContact C-N 3.34Å; S583-F585 PolarHBondContact O-N 3.21Å; S583-G586 PolarHBondContact O-N 3.35Å
584L40.9Very low39.5Very low137 Ų137110.1 Ų110.172%0.71767%0.673SS**Hα-helixtrans-73.2-21.6-174.7-141.780.8000114.3T580 I581 G586T580-L584 PolarHBondContact O-N 3.46Å; I581-L584 PolarHBondContact O-N 2.92Å; I581-L584 VanDerWaalsContact O-N 3.16Å; L584-G586 VanDerWaalsContact C-N 3.33Å
585F45.2Very low38.3Very low182 Ų182110 Ų11080%0.79867%0.669SS**THydrogen-bonded Turntrans-86.61.4178.5-77.4-83.1000114.2I581 S583 G587I581-F585 HydrophobicContact CG2-CD2 4.5Å; I581-F585 HydrophobicContact CG2-CE2 4.16Å; S583-F585 VanDerWaalsContact C-N 3.34Å; S583-F585 PolarHBondContact O-N 3.21Å; F585-G587 PolarHBondContact O-N 3.43Å
586G37Very low37Very low66 Ų66113.6 Ų113.668%0.6869%0.685SS**SBendtrans-82.182.8165.800000110.8S583 L584 G588S583-G586 PolarHBondContact O-N 3.35Å; L584-G586 VanDerWaalsContact C-N 3.33Å; G586-G588 PolarHBondContact O-N 3Å
587G30.6Very low36.1Very low82 Ų82111.4 Ų111.485%0.84570%0.698SS**  trans-60.6123.9-173.700000114.2F585F585-G587 PolarHBondContact O-N 3.43Å
588G28.4Very low34.9Very low75 Ų75112.4 Ų112.477%0.77371%0.709SS**  trans-178.487.3176.300000111.8G586G586-G588 PolarHBondContact O-N 3Å
589T29.2Very low33.8Very low137 Ų137117.9 Ų117.984%0.8473%0.729SS**  trans-114.8114.3-172.752.80000113.5
590T30.7Very low32.8Very low133 Ų133118.2 Ų118.282%0.81674%0.735SS**  trans-145.2136.115043.50000108.8
591P42.9Very low31.8Very low112 Ų112120 Ų12073%0.72775%0.746SS**  trans-84.7154.3176.336.1-34.9000111.7
592D27.9Very low30.7Very low168 Ų168123.6 Ų123.690%0.89876%0.761SS**  -174.7172.5105.7-105.8-32.9000111.2
593A28.2Very low30Very low88 Ų88127.4 Ų127.473%0.72777%0.765SS**  trans-134.4140.6-175.400000113.1
594K25.9Very low29.4Very low178 Ų178129.5 Ų129.577%0.77478%0.777SS**  trans-174.9134.9130.1-106.7166.3175-86.60115.5
595E24.1Very low28.7Very low129 Ų129127.3 Ų127.360%0.60377%0.773SS**  trans46124.2134.8-71.2-178.498.300123.7
596N23.8Very low27.8Very low149 Ų149126 Ų12680%0.79777%0.769SS**  trans73.4132.9138.2-57.1-24.5000120.1
597G24.6Very low27.3Very low78 Ų78130.6 Ų130.680%0.80477%0.771SS**  trans155.370.3173.600000113.8
598T23.5Very low27.1Very low133 Ų133130.5 Ų130.582%0.81676%0.761SS**  trans-72.6132.216146.10000109.2
599D25.3Very low27Very low152 Ų152136.2 Ų136.281%0.81377%0.768SS**  -165.1176.5112.5-119.8-42000115.5
600T24.2Very low26.9Very low119 Ų119134.5 Ų134.573%0.7377%0.768SS**  trans-100.7164.6-165.639.60000115.9
601V24.9Very low26.7Very low121 Ų121131.5 Ų131.573%0.73376%0.764SS**  trans92.7152.8140.5143.70000120.8
602Q25.4Very low26.8Very low177 Ų177131.6 Ų131.683%0.82776%0.764SS**  trans76.788165.7-88.7152.333.700121.3
603K25.8Very low26.9Very low177 Ų177133 Ų13377%0.7777%0.765SS**  -49.8151.9126.2-121.9-178.6-174.1-175.80110.2
604P28.9Very low27Very low127 Ų127132.3 Ų132.383%0.82577%0.766SS**  -138.2174.284.537.5-23.7000115.3
605S25.7Very low27.2Very low91 Ų91130.9 Ų130.964%0.63677%0.772SS**  trans-119.2156.8-178.651.30000110.9
606E27.1Very low27.6Very low153 Ų153129.2 Ų129.272%0.71578%0.781SS**  trans169.9156.6151.2-94.4-170.6163.900106.5
607K25.5Very low28.1Very low164 Ų164128.3 Ų128.371%0.71378%0.783SS**  cis-160.5173.8-1.7-109.8158.5179.3149.10105.4
608A26.3Very low28.3Very low79 Ų79129.1 Ų129.165%0.65378%0.782SS**  cis179-178.4-32.900000107.3
609E27.5Very low28.9Very low195 Ų195129.1 Ų129.191%0.91178%0.784SS**  trans73.5144169.6-53.3-175.7173.700116.7
610A26Very low29.3Very low102 Ų102131.4 Ų131.484%0.84379%0.79SS**  cis-139.1168.9-0.400000112.3
611G27Very low30Very low70 Ų70129.4 Ų129.472%0.72279%0.793SS**  trans-103.2-141.6179.700000114
612P45.3Very low30.3Very low113 Ų113133 Ų13373%0.73480%0.802SS**  cis-144.5-171.83.644.3-25000117.1
613E29.8Very low30.8Very low198 Ų198134.3 Ų134.393%0.92581%0.805SS**  trans77.1145.9148.3-84.8171-143.700124.2
614G29.8Very low31.2Very low73 Ų73135.8 Ų135.875%0.75381%0.811SS**  trans137.392.1175.100000114
615V30.5Very low31.7Very low148 Ų148138.5 Ų138.590%0.89781%0.813SS**  trans-133.7132.4-177.6178.60000112.7
616A32.5Very low32.7Very low94 Ų94142.9 Ų142.978%0.77782%0.82SS**  trans-150.1145.9158.400000109.8
617P35.3Very low33.7Very low131 Ų131141.5 Ų141.585%0.85183%0.825SS**  trans-98161.1-166.137.4-36.4000115.4
618A28.9Very low35.3Very low95 Ų95136.4 Ų136.479%0.78581%0.813SS**  trans-133151.8162.900000109.2
619P35.3Very low37.4Very low132 Ų132141.5 Ų141.586%0.85782%0.816SS**  trans-78.6164.7-167.531.6-36.7000114.8
620E33.5Very low39.9Very low200 Ų200138.3 Ų138.394%0.93580%0.799SS**  trans-64158.6169.4-53.4179.2117.700111.7
621G38.7Very low42.8Very low77 Ų77139.8 Ų139.879%0.79478%0.782SS**  trans169.9-33.6161.100000120.5
622E31.7Very low45.8Very low196 Ų196142.4 Ų142.492%0.91677%0.771SS**  trans-112.4121.6-170.4-69.2-158.1147.700115.1K624E622-K624 PolarHBondContact O-N 3.43Å
623K35.9Very low48Very low205 Ų205138.7 Ų138.789%0.89174%0.744SS**  trans-73.4104.5172-68.3177.8-179.6174.90109.8Q625K623-Q625 PolarHBondContact O-N 3.08Å
624K34.5Very low51Low209 Ų209132.2 Ų132.291%0.90972%0.718SS**  trans-59.2106.7165.9-78.8-178.4175.1175.80110E622E622-K624 PolarHBondContact O-N 3.43Å
625Q38.6Very low54Low184 Ų184130.8 Ų130.886%0.8669%0.692SS**PPolyproline II helixtrans-59145.3167.5-70.2176.5-24.800109.7K623K623-Q625 PolarHBondContact O-N 3.08Å
626K46.2Very low57.1Low182 Ų182130.7 Ų130.779%0.79168%0.681SS**PPolyproline II helixtrans-65.6140.6165.9-71.6178.9177.4176.70108.5A628K626-A628 PolarHBondContact O-N 3.49Å
627P48.8Very low60.1Low125 Ų125126.5 Ų126.581%0.81265%0.646SS**PPolyproline II helixtrans-65.1127.2174.727.2-33.5000110.2
628A58.6Low63Low56 Ų56122 Ų12246%0.46362%0.624SS.*PPolyproline II helixtrans-58.9141.8179.100000111.8L563 K626 K630L563-A628 HydrophobicContact CD2-CB 4.37Å; K626-A628 PolarHBondContact O-N 3.49Å; A628-K630 PolarHBondContact O-N 3.21Å
629R72Confident66.2Low186 Ų186120.4 Ų120.470%0.70260%0.604SS**EExtended strand (participates in β ladder)trans-85.9114.5-170.4-156.1172.6-174.4-175.90.1109.8V564V564-R629 WeakPolarHBondContact CB-O 3.39Å; V564-R629 PolarHBondContact N-O 3.13Å; V564-R629 PolarHBondContact O-N 2.97Å
630K79.8Confident69.1Low128 Ų128117.2 Ų117.256%0.55758%0.578SS**EExtended strand (participates in β ladder)trans-70.8129.6177.8-72.9-174.5161.7-152.40111.5E561 T562 L563 A628E561-K630 IonicContact OE2-NZ 3.42Å; E561-K630 PolarHBondContact OE2-NZ 3.5Å; T562-K630 WeakPolarHBondContact O-CA 3.32Å; L563-K630 HydrophobicContact CD2-CG 3.97Å; A628-K630 PolarHBondContact O-N 3.21Å
631R85.8Confident72Confident133 Ų133112.2 Ų112.250%0.50256%0.557SS.*EExtended strand (participates in β ladder)trans-103115.5169.5-172.8176.8-170.7175.61.9109.1E561 T562 V564 M633E561-R631 WeakPolarHBondContact CA-O 3.36Å; T562-R631 HydrophobicContact CG2-CB 4.43Å; T562-R631 PolarHBondContact N-O 2.78Å; T562-R631 PolarHBondContact O-N 3.34Å; V564-R631 HydrophobicContact CG2-CB 3.66Å; R631-M633 HydrophobicContact CG-CE 4.34Å; R631-M633 VanDerWaalsContact NE-CE 3.35Å
632R90.8Very high74.7Confident126 Ų126110.9 Ų110.948%0.47553%0.533SS..EExtended strand (participates in β ladder)trans-96.1130.6175.8-179.7-179167.5-164.8-3.8109.9E557 V559 F560 E561 V634E557-R632 IonicContact OE1-NH2 2.97Å; E557-R632 PolarHBondContact OE1-NH2 2.73Å; V559-R632 HydrophobicContact CG1-CG 3.97Å; V559-R632 VanDerWaalsContact CG1-NE 3.29Å; F560-R632 CarbonylContact O-C 3.58Å; F560-R632 WeakPolarHBondContact O-CA 3.47Å; E561-R632 HydrophobicContact CG-CB 4.27Å; E561-R632 HydrophobicContact CG-CG 4.37Å; R632-V634 HydrophobicContact CG-CG2 4.15Å
633M91Very high77.6Confident34 Ų34103.9 Ų103.917%0.16750%0.503CS..EExtended strand (participates in β ladder)trans-107.2150.7166.7-58.8-64.2-166.400109.4Y531 Y534 F560 R631Y531-M633 HydrophobicContact CD1-CB 4.34Å; Y531-M633 HydrophobicContact CD1-CG 3.92Å; Y531-M633 HydrophobicContact CD2-CB 4.37Å; Y531-M633 HydrophobicContact CE1-CB 4.1Å; Y531-M633 HydrophobicContact CE1-CE 3.99Å; Y531-M633 HydrophobicContact CE1-CG 3.61Å; Y531-M633 HydrophobicContact CE1-SD 4.08Å; Y531-M633 HydrophobicContact CE2-CB 4.1Å; Y531-M633 HydrophobicContact CG-CB 4.49Å; Y534-M633 HydrophobicContact CD1-CG 3.96Å; Y534-M633 HydrophobicContact CE1-CE 3.97Å; Y534-M633 HydrophobicContact CE1-CG 3.5Å; Y534-M633 VanDerWaalsContact OH-CE 3.27Å; Y534-M633 WeakPolarHBondContact OH-CE 3.22Å; F560-M633 HydrophobicContact CB-CB 4.38Å; F560-M633 PolarHBondContact N-O 2.86Å; F560-M633 PolarHBondContact O-N 3.16Å; R631-M633 HydrophobicContact CG-CE 4.34Å; R631-M633 VanDerWaalsContact NE-CE 3.35Å
634V92.4Very high80.2Confident63 Ų6397.2 Ų97.238%0.38248%0.477SS..EExtended strand (participates in β ladder)trans-142121.5179-174.90000108.1E557 S558 V559 R632E557-V634 HydrophobicContact CB-CG1 3.67Å; E557-V634 HydrophobicContact CG-CG1 4.08Å; S558-V634 WeakPolarHBondContact O-CA 3.32Å; V559-V634 HydrophobicContact CG2-CG1 4.39Å; V559-V634 HydrophobicContact CG2-CG2 4.35Å; R632-V634 HydrophobicContact CG-CG2 4.15Å
635E93.4Very high82.8Confident43 Ų4388.1 Ų88.120%0.20144%0.438CS..EExtended strand (participates in β ladder)trans-108.8138172.8-65.1-67.1118.700109.4K530 Y531 E557 S558K530-E635 HydrophobicContact CD-CG 4.38Å; K530-E635 WeakPolarHBondContact CD-OE2 3.33Å; K530-E635 IonicContact NZ-OE1 2.67Å; K530-E635 PolarHBondContact NZ-OE1 3.41Å; K530-E635 IonicContact NZ-OE2 3.92Å; K530-E635 PolarHBondContact NZ-OE2 3.18Å; Y531-E635 HydrophobicContact CD2-CG 4.28Å; Y531-E635 HydrophobicContact CE2-CG 3.69Å; Y531-E635 WeakPolarHBondContact CE2-OE1 3.35Å; Y531-E635 PolarHBondContact OH-OE1 2.86Å; E557-E635 CarbonylContact C-O 3.39Å; E557-E635 VanDerWaalsContact CA-O 3.25Å; E557-E635 WeakPolarHBondContact CA-O 3.39Å; S558-E635 PolarHBondContact N-O 3.45Å; S558-E635 PolarHBondContact O-N 2.96Å
636E95.1Very high85.3Confident145 Ų14579.5 Ų79.568%0.67840%0.399SS*.EExtended strand (participates in β ladder)trans-79.3134.6168.9-171.1154.9-138.300109.8R555R555-E636 WeakPolarHBondContact CB-OE1 3.34Å
637I96.5Very high87.3Confident6 Ų673.6 Ų73.63%0.03138%0.379CS..PPolyproline II helixtrans-101.1136.2-177-66-54.8000109.2L521 V524 V556 V639L521-I637 HydrophobicContact CB-CG2 3.91Å; L521-I637 HydrophobicContact CD2-CG2 4.29Å; L521-I637 HydrophobicContact CG-CG2 4.49Å; V524-I637 HydrophobicContact CG2-CD1 4.36Å; V524-I637 HydrophobicContact CG2-CG1 4.48Å; V524-I637 HydrophobicContact CG2-CG2 3.72Å; V556-I637 HydrophobicContact CB-CB 4.32Å; V556-I637 HydrophobicContact CG1-CB 4.11Å; V556-I637 HydrophobicContact CG1-CG2 4.38Å; V556-I637 PolarHBondContact O-N 3.36Å; I637-V639 WeakPolarHBondContact O-CG2 3.41Å; I637-V639 PolarHBondContact O-N 3.48Å
638G95.1Very high89.2Confident38 Ų3871.3 Ų71.339%0.39236%0.359SS..EExtended strand (participates in β ladder)trans-64.3130.2178.300000111L521 K522L521-G638 CarbonylContact C-O 3.53Å; L521-G638 WeakPolarHBondContact CA-O 3.38Å; K522-G638 PolarHBondContact N-O 3.41Å; K522-G638 PolarHBondContact O-N 2.9Å
639V96.8Very high90.6Very high61 Ų6169.9 Ų69.937%0.3734%0.344SS..EExtended strand (participates in β ladder)trans-116.4132.4-178.5-176.70000110.3V519 L521 L553 V556 I637 L641V519-V639 HydrophobicContact CG1-CG1 3.83Å; L521-V639 HydrophobicContact CD2-CG2 4.05Å; L553-V639 HydrophobicContact CD2-CG1 4.2Å; V556-V639 HydrophobicContact CB-CG2 3.94Å; V556-V639 HydrophobicContact CG2-CG2 3.66Å; I637-V639 WeakPolarHBondContact O-CG2 3.41Å; I637-V639 PolarHBondContact O-N 3.48Å; V639-L641 HydrophobicContact CG1-CD2 3.57Å; V639-L641 HydrophobicContact CG1-CG 4.07Å
640E96.3Very high91.5Very high65 Ų6563.4 Ų63.430%0.30433%0.326SS..EExtended strand (participates in β ladder)trans-118.6120.4165.7-179.8-170.2133.300108.6K520 K522K520-E640 HydrophobicContact CB-CB 4.26Å; K520-E640 WeakPolarHBondContact CD-OE1 3.37Å; K520-E640 WeakPolarHBondContact CE-OE1 3.34Å; K520-E640 PolarHBondContact N-O 2.86Å; K520-E640 IonicContact NZ-OE1 2.8Å; K520-E640 PolarHBondContact NZ-OE1 3.45Å; K520-E640 PolarHBondContact O-N 3.37Å; K522-E640 IonicContact NZ-OE2 2.67Å; K522-E640 PolarHBondContact NZ-OE2 2.92Å
641L94.6Very high92.1Very high94 Ų9462.8 Ų62.849%0.49233%0.325SS..EExtended strand (participates in β ladder)trans-97.5126.9178.8-57.9-177.9000110T517 V519 L553 V639T517-L641 HydrophobicContact CG2-CB 4.04Å; T517-L641 HydrophobicContact CG2-CD2 4.13Å; V519-L641 HydrophobicContact CB-CD2 4.39Å; V519-L641 HydrophobicContact CG1-CD2 4.14Å; V519-L641 HydrophobicContact CG2-CD2 3.83Å; L553-L641 HydrophobicContact CD2-CD2 4.17Å; V639-L641 HydrophobicContact CG1-CD2 3.57Å; V639-L641 HydrophobicContact CG1-CG 4.07Å
642V94.5Very high92.5Very high50 Ų5060.6 Ų60.630%0.30332%0.323SS..EExtended strand (participates in β ladder)trans-112.8105.9167.9-177.90000107.8T517 T518 L644T517-V642 CarbonylContact C-O 3.57Å; T517-V642 VanDerWaalsContact CA-O 3.27Å; T517-V642 WeakPolarHBondContact CA-O 3.2Å; T517-V642 WeakPolarHBondContact CG2-O 3.33Å; T518-V642 PolarHBondContact N-O 3.18Å; T518-V642 PolarHBondContact O-N 3.09Å; V642-L644 HydrophobicContact CG1-CD2 4.02Å
643V92.3Very high92.6Very high48 Ų4859 Ų5929%0.29132%0.32SS..EExtended strand (participates in β ladder)trans-74.5134.1179.4-179.50000109.7D645 L646V643-D645 WeakPolarHBondContact CG1-OD1 3.35Å; V643-L646 WeakPolarHBondContact CG1-O 3.41Å
644L91.3Very high92.7Very high66 Ų6657.9 Ų57.935%0.34632%0.315SS..SBendtrans-123.2-7.1-169.1-60.8-179.7000114.5S513 N515 L516 V642S513-L644 PolarHBondContact OG-O 2.91Å; N515-L644 HydrophobicContact CB-CB 4.03Å; N515-L644 HydrophobicContact CB-CD1 3.98Å; N515-L644 CarbonylContact O-C 3.54Å; N515-L644 VanDerWaalsContact O-C 3.22Å; N515-L644 WeakPolarHBondContact O-CB 3.33Å; L516-L644 PolarHBondContact O-N 2.8Å; V642-L644 HydrophobicContact CG1-CD2 4.02Å
645D89.5Confident92.9Very high17 Ų1757.6 Ų57.69%0.09132%0.319CS..SBendtrans-88.9-57174.861.6-24.3000110.8A183 R186 N515 L516 V643A183-D645 PolarHBondContact N-OD2 3.45Å; R186-D645 IonicContact CZ-OD1 3.3Å; R186-D645 IonicContact CZ-OD2 2.89Å; R186-D645 IonicContact NH2-OD1 2.81Å; R186-D645 PolarHBondContact NH2-OD1 2.87Å; R186-D645 IonicContact NH2-OD2 2.76Å; R186-D645 PolarHBondContact NH2-OD2 3.15Å; N515-D645 PolarHBondContact O-N 3.41Å; L516-D645 HydrophobicContact CD2-CB 4.17Å; L516-D645 WeakPolarHBondContact CD2-OD2 3.18Å; V643-D645 WeakPolarHBondContact CG1-OD1 3.35Å
646L90.8Very high93Very high4 Ų460 Ų602%0.02133%0.33CS..  trans-160.8120.7169.8-177.868.3000108.5G105 Q107 R131 T133 A183 R186 V643G105-L646 VanDerWaalsContact CA-CD2 3.5Å; Q107-L646 HydrophobicContact CG-CD1 4.09Å; R131-L646 HydrophobicContact CB-CD1 4.44Å; T133-L646 HydrophobicContact CG2-CD1 3.61Å; T133-L646 HydrophobicContact CG2-CD2 3.98Å; T133-L646 HydrophobicContact CG2-CG 4.41Å; A183-L646 HydrophobicContact CB-CB 3.89Å; A183-L646 HydrophobicContact CB-CD2 4.41Å; R186-L646 PolarHBondContact NH1-O 2.86Å; R186-L646 PolarHBondContact NH2-O 3.24Å; V643-L646 WeakPolarHBondContact CG1-O 3.41Å
647P87.9Confident93Very high58 Ų5853.7 Ų53.738%0.37730%0.302SS..PPolyproline II helixtrans-64.7145.3174.226.6-33.8000111.4R131R131-P647 PolarHBondContact NE-O 3.15Å
648D88.1Confident93.1Very high76 Ų7655 Ų5541%0.40631%0.31SS..PPolyproline II helixtrans-62.1159169.9-62.7-45.6000110.6R186 Q190R186-D648 IonicContact CZ-OD1 2.63Å; R186-D648 IonicContact NH1-OD1 2.62Å; R186-D648 PolarHBondContact NH1-OD1 2.95Å; R186-D648 IonicContact NH1-OD2 2.64Å; Q190-D648 PolarHBondContact NE2-OD1 3.49Å
649L89.1Confident93.1Very high26 Ų2658 Ų5814%0.13631%0.314CS..PPolyproline II helixtrans-59.5133.8170.8-86.386.2000109.4M194 K653 L654M194-L649 HydrophobicContact CE-CD2 4.15Å; L649-K653 HydrophobicContact CD2-CB 4.28Å; L649-L654 HydrophobicContact CB-CB 4.39Å
650P90.5Very high93Very high51 Ų5158 Ų5833%0.33131%0.309SS..PPolyproline II helixtrans-51.9143.2168.4-28.136.3000111.4D652 K653 L654P650-D652 WeakPolarHBondContact CB-OD1 3.49Å; P650-D652 PolarHBondContact O-N 2.87Å; P650-D652 VanDerWaalsContact O-N 3.15Å; P650-K653 HydrophobicContact CB-CB 4.4Å; P650-K653 HydrophobicContact CB-CG 4.19Å; P650-K653 HydrophobicContact CG-CG 4.36Å; P650-K653 CarbonylContact O-C 3.52Å; P650-K653 WeakPolarHBondContact O-CA 3.42Å; P650-K653 WeakPolarHBondContact O-CB 3.49Å; P650-K653 PolarHBondContact O-N 2.95Å; P650-L654 PolarHBondContact O-N 3.4Å
651E92.2Very high92.9Very high114 Ų11455.3 Ų55.353%0.53330%0.297SS..Hα-helixtrans-61.8-29.2-170.5-164.878.9154.900112.6R193 A655R193-E651 IonicContact CZ-OE1 2.69Å; R193-E651 IonicContact CZ-OE2 3.14Å; R193-E651 IonicContact NH1-OE1 2.73Å; R193-E651 PolarHBondContact NH1-OE1 3.09Å; R193-E651 IonicContact NH1-OE2 2.75Å; R193-E651 PolarHBondContact NH1-OE2 3.3Å; R193-E651 IonicContact NH2-OE1 3.88Å; R193-E651 PolarHBondContact NH2-OE1 2.86Å; R193-E651 IonicContact NH2-OE2 2.66Å; E651-A655 WeakPolarHBondContact O-CB 3.24Å; E651-A655 PolarHBondContact O-N 3.48Å
652D94.3Very high92.9Very high87 Ų8755.4 Ų55.447%0.46530%0.295SS..Hα-helixtrans-67.2-38.7171.876-70.3000112.1P650 A655 Q656P650-D652 WeakPolarHBondContact CB-OD1 3.49Å; P650-D652 PolarHBondContact O-N 2.87Å; P650-D652 VanDerWaalsContact O-N 3.15Å; D652-A655 PolarHBondContact O-N 3.39Å; D652-Q656 WeakPolarHBondContact O-CG 3.39Å; D652-Q656 PolarHBondContact O-N 2.62Å; D652-Q656 PolarHBondContact O-NE2 3.15Å; D652-Q656 PolarHBondContact OD2-NE2 2.9Å
653K92.9Very high92.9Very high93 Ų9355.5 Ų55.540%0.40429%0.293SS..Hα-helixtrans-72.1-40.7177.9-64.9-58.1177.6-174.70111.7L649 P650 A655 Q656 S657L649-K653 HydrophobicContact CD2-CB 4.28Å; P650-K653 HydrophobicContact CB-CB 4.4Å; P650-K653 HydrophobicContact CB-CG 4.19Å; P650-K653 HydrophobicContact CG-CG 4.36Å; P650-K653 CarbonylContact O-C 3.52Å; P650-K653 WeakPolarHBondContact O-CA 3.42Å; P650-K653 WeakPolarHBondContact O-CB 3.49Å; P650-K653 PolarHBondContact O-N 2.95Å; K653-A655 VanDerWaalsContact C-N 3.32Å; K653-A655 PolarHBondContact O-N 3.49Å; K653-Q656 WeakPolarHBondContact O-CB 3.31Å; K653-Q656 PolarHBondContact O-N 2.8Å; K653-S657 PolarHBondContact O-N 3.15Å; K653-S657 PolarHBondContact O-OG 3.39Å
654L94.1Very high92.9Very high10 Ų1053.7 Ų53.75%0.05228%0.282CS..Hα-helixtrans-60.2-43170.2-17962.6000111.2R193 M194 L649 P650 S657 V658R193-L654 HydrophobicContact CG-CD2 4.39Å; M194-L654 HydrophobicContact CE-CD1 3.61Å; M194-L654 HydrophobicContact CG-CD1 3.6Å; M194-L654 HydrophobicContact SD-CD1 4.46Å; L649-L654 HydrophobicContact CB-CB 4.39Å; P650-L654 PolarHBondContact O-N 3.4Å; L654-S657 PolarHBondContact O-N 3.11Å; L654-V658 HydrophobicContact CD1-CG2 4.42Å; L654-V658 HydrophobicContact CG-CG2 4.45Å; L654-V658 WeakPolarHBondContact O-CB 3.46Å; L654-V658 VanDerWaalsContact O-CG2 3.24Å; L654-V658 WeakPolarHBondContact O-CG2 3.45Å; L654-V658 PolarHBondContact O-N 3.3Å
655A95.9Very high93Very high58 Ų5851.9 Ų51.948%0.47927%0.274SS..Hα-helixtrans-63.6-39.317500000112.8E651 D652 K653 V658 Q659E651-A655 WeakPolarHBondContact O-CB 3.24Å; E651-A655 PolarHBondContact O-N 3.48Å; D652-A655 PolarHBondContact O-N 3.39Å; K653-A655 VanDerWaalsContact C-N 3.32Å; K653-A655 PolarHBondContact O-N 3.49Å; A655-V658 PolarHBondContact O-N 3.47Å; A655-Q659 WeakPolarHBondContact O-CB 3.3Å; A655-Q659 PolarHBondContact O-N 2.89Å
656Q95.6Very high93.1Very high93 Ų9355.9 Ų55.944%0.43530%0.295SS..Hα-helixtrans-59.8-45.8172.2-76.9151.864.900111.4D652 K653 K660D652-Q656 WeakPolarHBondContact O-CG 3.39Å; D652-Q656 PolarHBondContact O-N 2.62Å; D652-Q656 PolarHBondContact O-NE2 3.15Å; D652-Q656 PolarHBondContact OD2-NE2 2.9Å; K653-Q656 WeakPolarHBondContact O-CB 3.31Å; K653-Q656 PolarHBondContact O-N 2.8Å; Q656-K660 WeakPolarHBondContact O-CB 3.25Å; Q656-K660 PolarHBondContact O-N 2.84Å
657S95.6Very high93.1Very high12 Ų1260.8 Ų60.88%0.08431%0.313CS..Hα-helixtrans-65-42.8175.4-70.30000113E148 K653 L654 K660 L661E148-S657 VanDerWaalsContact OE1-CB 3.23Å; E148-S657 WeakPolarHBondContact OE1-CB 3.5Å; E148-S657 PolarHBondContact OE1-OG 3.36Å; K653-S657 PolarHBondContact O-N 3.15Å; K653-S657 PolarHBondContact O-OG 3.39Å; L654-S657 PolarHBondContact O-N 3.11Å; S657-K660 PolarHBondContact O-N 3.26Å; S657-L661 WeakPolarHBondContact O-CG 3.32Å; S657-L661 PolarHBondContact O-N 3.03Å
658V97Very high93.2Very high34 Ų3459.7 Ų59.721%0.20630%0.304CS..Hα-helixtrans-57.4-52.2174.9167.60000110.5M194 L654 A655 K660 L661 Q662M194-V658 HydrophobicContact CG-CG2 4.4Å; L654-V658 HydrophobicContact CD1-CG2 4.42Å; L654-V658 HydrophobicContact CG-CG2 4.45Å; L654-V658 WeakPolarHBondContact O-CB 3.46Å; L654-V658 VanDerWaalsContact O-CG2 3.24Å; L654-V658 WeakPolarHBondContact O-CG2 3.45Å; L654-V658 PolarHBondContact O-N 3.3Å; A655-V658 PolarHBondContact O-N 3.47Å; V658-K660 PolarHBondContact O-N 2.86Å; V658-L661 PolarHBondContact O-N 2.99Å; V658-Q662 HydrophobicContact CG1-CG 4.45Å; V658-Q662 WeakPolarHBondContact O-CB 3.43Å; V658-Q662 VanDerWaalsContact O-CG 3.31Å; V658-Q662 WeakPolarHBondContact O-CG 3.4Å; V658-Q662 PolarHBondContact O-N 3.43Å
659Q96.3Very high93.3Very high102 Ų10260.7 Ų60.748%0.47731%0.309SS..Hα-helixtrans-60.1-45.7178.9-174.763.75700111.2A655 L661 Q662 D663A655-Q659 WeakPolarHBondContact O-CB 3.3Å; A655-Q659 PolarHBondContact O-N 2.89Å; Q659-L661 VanDerWaalsContact C-N 3.33Å; Q659-L661 PolarHBondContact O-N 3.41Å; Q659-Q662 PolarHBondContact O-N 2.91Å; Q659-Q662 VanDerWaalsContact O-N 3.16Å; Q659-D663 PolarHBondContact NE2-OD1 3.49Å; Q659-D663 VanDerWaalsContact O-CB 3.3Å; Q659-D663 WeakPolarHBondContact O-CB 3.4Å; Q659-D663 PolarHBondContact O-N 3.45Å
660K94.3Very high93.4Very high60 Ų6065.6 Ų65.626%0.26133%0.331SS..Hα-helixtrans-57.9-39.4177.2173.8-173172.4-164.10113.1Q143 F144 E148 Q656 S657 V658 L664Q143-K660 PolarHBondContact O-NZ 2.79Å; F144-K660 HydrophobicContact CE1-CD 4.44Å; E148-K660 WeakPolarHBondContact OE1-CD 3.46Å; E148-K660 IonicContact OE1-NZ 2.78Å; E148-K660 PolarHBondContact OE1-NZ 3.39Å; E148-K660 IonicContact OE2-NZ 3.47Å; E148-K660 PolarHBondContact OE2-NZ 3.41Å; Q656-K660 WeakPolarHBondContact O-CB 3.25Å; Q656-K660 PolarHBondContact O-N 2.84Å; S657-K660 PolarHBondContact O-N 3.26Å; V658-K660 PolarHBondContact O-N 2.86Å; K660-L664 WeakPolarHBondContact O-CD1 3.38Å; K660-L664 WeakPolarHBondContact O-CG 3.39Å; K660-L664 PolarHBondContact O-N 3.25Å
661L95Very high93.4Very high8 Ų866.3 Ų66.34%0.04233%0.329CS..Hα-helixtrans-76.9-32.4175.3-64.2-163.2000113F144 E148 M152 M194 S657 V658 Q659 L664 T665F144-L661 HydrophobicContact CE1-CD2 4.45Å; E148-L661 WeakPolarHBondContact O-CD1 3.47Å; M152-L661 HydrophobicContact CE-CD2 3.66Å; M152-L661 HydrophobicContact CG-CD1 4.29Å; M152-L661 HydrophobicContact CG-CD2 3.77Å; M152-L661 HydrophobicContact SD-CD2 4.45Å; M194-L661 HydrophobicContact CB-CD1 4.12Å; S657-L661 WeakPolarHBondContact O-CG 3.32Å; S657-L661 PolarHBondContact O-N 3.03Å; V658-L661 PolarHBondContact O-N 2.99Å; Q659-L661 VanDerWaalsContact C-N 3.33Å; Q659-L661 PolarHBondContact O-N 3.41Å; L661-L664 HydrophobicContact CD2-CD1 4.37Å; L661-T665 WeakPolarHBondContact O-CB 3.2Å; L661-T665 PolarHBondContact O-N 3.41Å; L661-T665 VanDerWaalsContact O-N 3.09Å; L661-T665 PolarHBondContact O-OG1 3.45Å
662Q94.4Very high93.3Very high97 Ų9765.1 Ų65.145%0.45332%0.323SS..Hα-helixtrans-66.5-47.7173.3-73.6175.10.900111.2V658 Q659 L664 T665 L666V658-Q662 HydrophobicContact CG1-CG 4.45Å; V658-Q662 WeakPolarHBondContact O-CB 3.43Å; V658-Q662 VanDerWaalsContact O-CG 3.31Å; V658-Q662 WeakPolarHBondContact O-CG 3.4Å; V658-Q662 PolarHBondContact O-N 3.43Å; Q659-Q662 PolarHBondContact O-N 2.91Å; Q659-Q662 VanDerWaalsContact O-N 3.16Å; Q662-L664 VanDerWaalsContact C-N 3.3Å; Q662-L664 PolarHBondContact O-N 3.41Å; Q662-T665 CarbonylContact O-C 3.6Å; Q662-T665 WeakPolarHBondContact O-CA 3.48Å; Q662-T665 WeakPolarHBondContact O-CB 3.31Å; Q662-T665 PolarHBondContact O-N 3.38Å; Q662-L666 WeakPolarHBondContact O-CG 3.37Å; Q662-L666 PolarHBondContact O-N 3.43Å
663D93.5Very high93.2Very high51 Ų5164.3 Ų64.327%0.27332%0.317SS..Hα-helixtrans-49-46.8172.4-95.741.4000113Q659 R667Q659-D663 PolarHBondContact NE2-OD1 3.49Å; Q659-D663 VanDerWaalsContact O-CB 3.3Å; Q659-D663 WeakPolarHBondContact O-CB 3.4Å; Q659-D663 PolarHBondContact O-N 3.45Å; D663-R667 WeakPolarHBondContact O-CG 3.31Å; D663-R667 PolarHBondContact O-N 3.1Å; D663-R667 IonicContact OD2-CZ 2.77Å; D663-R667 IonicContact OD2-NH2 3.91Å; D663-R667 PolarHBondContact OD2-NH2 3.07Å
664L92.8Very high93.3Very high10 Ų1063 Ų635%0.05231%0.309CS..Hα-helixtrans-67.8-37.1176.2-69.9163.4000111.6F144 M152 K660 L661 Q662 R667 D668F144-L664 HydrophobicContact CE1-CD1 3.87Å; F144-L664 HydrophobicContact CZ-CD1 3.97Å; M152-L664 HydrophobicContact CE-CD1 4.4Å; K660-L664 WeakPolarHBondContact O-CD1 3.38Å; K660-L664 WeakPolarHBondContact O-CG 3.39Å; K660-L664 PolarHBondContact O-N 3.25Å; L661-L664 HydrophobicContact CD2-CD1 4.37Å; Q662-L664 VanDerWaalsContact C-N 3.3Å; Q662-L664 PolarHBondContact O-N 3.41Å; L664-R667 PolarHBondContact O-N 3.35Å; L664-D668 PolarHBondContact O-N 3.03Å
665T92.4Very high93.2Very high29 Ų2966.2 Ų66.218%0.17832%0.324CS..Hα-helixtrans-69.6-36.1178.4-51.30000112.4R79 L661 Q662 D668 L669R79-T665 PolarHBondContact NH2-OG1 3.21Å; L661-T665 WeakPolarHBondContact O-CB 3.2Å; L661-T665 PolarHBondContact O-N 3.41Å; L661-T665 VanDerWaalsContact O-N 3.09Å; L661-T665 PolarHBondContact O-OG1 3.45Å; Q662-T665 CarbonylContact O-C 3.6Å; Q662-T665 WeakPolarHBondContact O-CA 3.48Å; Q662-T665 WeakPolarHBondContact O-CB 3.31Å; Q662-T665 PolarHBondContact O-N 3.38Å; T665-D668 PolarHBondContact O-N 2.91Å; T665-L669 HydrophobicContact CG2-CD1 4.23Å; T665-L669 WeakPolarHBondContact O-CB 3.21Å; T665-L669 VanDerWaalsContact O-CG 3.27Å; T665-L669 WeakPolarHBondContact O-CG 3.36Å; T665-L669 PolarHBondContact O-N 2.82Å
666L92.2Very high93.1Very high100 Ų10069 Ų6952%0.52433%0.325SS..Hα-helixtrans-63.7-44.7172.8-67.3172.4000110.9Q662 D668 L669 E670Q662-L666 WeakPolarHBondContact O-CG 3.37Å; Q662-L666 PolarHBondContact O-N 3.43Å; L666-D668 PolarHBondContact O-N 3.39Å; L666-L669 PolarHBondContact O-N 2.87Å; L666-E670 WeakPolarHBondContact O-CB 3.43Å; L666-E670 VanDerWaalsContact O-CG 3.3Å; L666-E670 WeakPolarHBondContact O-CG 3.41Å; L666-E670 PolarHBondContact O-N 2.97Å
667R91.1Very high93.1Very high108 Ų10864.7 Ų64.741%0.40831%0.306SS..Hα-helixtrans-62.2-43.1176.4-67.8171.6-162.4117.115.3112.6D663 L664 L669 E670 K671D663-R667 WeakPolarHBondContact O-CG 3.31Å; D663-R667 PolarHBondContact O-N 3.1Å; D663-R667 IonicContact OD2-CZ 2.77Å; D663-R667 IonicContact OD2-NH2 3.91Å; D663-R667 PolarHBondContact OD2-NH2 3.07Å; L664-R667 PolarHBondContact O-N 3.35Å; R667-L669 VanDerWaalsContact C-N 3.33Å; R667-L669 PolarHBondContact O-N 3.19Å; R667-E670 PolarHBondContact O-N 2.76Å; R667-K671 WeakPolarHBondContact O-CB 3.46Å; R667-K671 PolarHBondContact O-N 3.49Å
668D90.4Very high93.1Very high34 Ų3464.8 Ų64.818%0.18231%0.308CS..Hα-helixtrans-60.8-42.1175.9-64.9-24.4000111.2R79 L664 T665 L666 Q672R79-D668 IonicContact CZ-OD2 3.46Å; R79-D668 IonicContact NE-OD2 3.98Å; R79-D668 PolarHBondContact NE-OD2 2.96Å; R79-D668 IonicContact NH2-OD2 3.47Å; R79-D668 PolarHBondContact NH2-OD2 2.91Å; L664-D668 PolarHBondContact O-N 3.03Å; T665-D668 PolarHBondContact O-N 2.91Å; L666-D668 PolarHBondContact O-N 3.39Å; D668-Q672 WeakPolarHBondContact O-CB 3.37Å; D668-Q672 PolarHBondContact O-N 2.94Å
669L90.4Very high93.1Very high97 Ų9767.8 Ų67.851%0.50832%0.322SS..Hα-helixtrans-70.3-42.2178.1-72.2169.8000112.9T665 L666 R667 K671 Q672 E673T665-L669 HydrophobicContact CG2-CD1 4.23Å; T665-L669 WeakPolarHBondContact O-CB 3.21Å; T665-L669 VanDerWaalsContact O-CG 3.27Å; T665-L669 WeakPolarHBondContact O-CG 3.36Å; T665-L669 PolarHBondContact O-N 2.82Å; L666-L669 PolarHBondContact O-N 2.87Å; R667-L669 VanDerWaalsContact C-N 3.33Å; R667-L669 PolarHBondContact O-N 3.19Å; L669-K671 VanDerWaalsContact C-N 3.31Å; L669-K671 PolarHBondContact O-N 3.29Å; L669-Q672 PolarHBondContact O-N 3.2Å; L669-E673 PolarHBondContact O-N 2.82Å
670E91.4Very high93.1Very high130 Ų13065.3 Ų65.361%0.60732%0.316SS*.Hα-helixtrans-59.5-43.2174.1-76.4174.316700111.1L666 R667 R674L666-E670 WeakPolarHBondContact O-CB 3.43Å; L666-E670 VanDerWaalsContact O-CG 3.3Å; L666-E670 WeakPolarHBondContact O-CG 3.41Å; L666-E670 PolarHBondContact O-N 2.97Å; R667-E670 PolarHBondContact O-N 2.76Å; E670-R674 WeakPolarHBondContact O-CB 3.14Å; E670-R674 PolarHBondContact O-N 2.86Å
671K89.6Confident93.2Very high65 Ų6562.4 Ų62.428%0.28330%0.304SS..Hα-helixtrans-61.8-51173-177.4-178171.5-177.20111.2E78 R667 L669 E673 R674 E675E78-K671 IonicContact OE1-NZ 3.18Å; E78-K671 PolarHBondContact OE1-NZ 2.9Å; E78-K671 IonicContact OE2-NZ 3.4Å; E78-K671 PolarHBondContact OE2-NZ 3.47Å; R667-K671 WeakPolarHBondContact O-CB 3.46Å; R667-K671 PolarHBondContact O-N 3.49Å; L669-K671 VanDerWaalsContact C-N 3.31Å; L669-K671 PolarHBondContact O-N 3.29Å; K671-E673 VanDerWaalsContact C-N 3.33Å; K671-E673 PolarHBondContact O-N 3.05Å; K671-R674 WeakPolarHBondContact O-CA 3.41Å; K671-R674 WeakPolarHBondContact O-CB 3.38Å; K671-R674 PolarHBondContact O-N 3.4Å; K671-E675 WeakPolarHBondContact CE-OE1 3.35Å; K671-E675 WeakPolarHBondContact CE-OE2 3.44Å; K671-E675 HydrophobicContact CG-CG 4.42Å; K671-E675 IonicContact NZ-OE1 3.05Å; K671-E675 PolarHBondContact O-N 2.64Å
672Q89.6Confident93.3Very high89 Ų8966.2 Ų66.242%0.41632%0.321SS..Hα-helixtrans-60.6-39.6-178.5-171178-54.700112.1D668 L669 K676D668-Q672 WeakPolarHBondContact O-CB 3.37Å; D668-Q672 PolarHBondContact O-N 2.94Å; L669-Q672 PolarHBondContact O-N 3.2Å; Q672-K676 WeakPolarHBondContact O-CB 3.3Å; Q672-K676 PolarHBondContact O-N 2.82Å
673E92.7Very high93.5Very high70 Ų7064.4 Ų64.433%0.32732%0.323SS..Hα-helixtrans-71.1-29.1174.2-90.3-72.6130.200113.2L669 K671 K676 A677 T729 K733L669-E673 PolarHBondContact O-N 2.82Å; K671-E673 VanDerWaalsContact C-N 3.33Å; K671-E673 PolarHBondContact O-N 3.05Å; E673-K676 WeakPolarHBondContact OE1-CD 3.29Å; E673-K676 WeakPolarHBondContact OE1-CE 3.27Å; E673-K676 IonicContact OE1-NZ 3.84Å; E673-K676 PolarHBondContact OE1-NZ 3.44Å; E673-A677 VanDerWaalsContact O-CB 3.32Å; E673-A677 WeakPolarHBondContact O-CB 3.16Å; E673-A677 PolarHBondContact O-N 3.32Å; E673-A677 VanDerWaalsContact O-N 3.08Å; E673-T729 HydrophobicContact CB-CG2 4.39Å; E673-T729 WeakPolarHBondContact O-CG2 3.36Å; E673-K733 IonicContact OE2-NZ 2.68Å; E673-K733 PolarHBondContact OE2-NZ 2.77Å
674R93.9Very high93.7Very high65 Ų6562.8 Ų62.825%0.24531%0.313CS..Hα-helixtrans-67.6-48.8172.1-162.7-164.184.1921.1111.5E670 K671 A677 A678 G724 V725 A727 T729 L732E670-R674 WeakPolarHBondContact O-CB 3.14Å; E670-R674 PolarHBondContact O-N 2.86Å; K671-R674 WeakPolarHBondContact O-CA 3.41Å; K671-R674 WeakPolarHBondContact O-CB 3.38Å; K671-R674 PolarHBondContact O-N 3.4Å; R674-A677 WeakPolarHBondContact O-CB 3.4Å; R674-A677 PolarHBondContact O-N 2.97Å; R674-A677 VanDerWaalsContact O-N 3.16Å; R674-A678 PolarHBondContact O-N 3.37Å; R674-G724 PolarHBondContact NH1-O 3.47Å; R674-G724 VanDerWaalsContact NH1-O 3.09Å; R674-V725 PolarHBondContact NH1-O 3.47Å; R674-V725 VanDerWaalsContact NH1-O 3.08Å; R674-V725 PolarHBondContact NH2-O 3.23Å; R674-A727 WeakPolarHBondContact CD-O 2.99Å; R674-A727 PolarHBondContact NH1-O 2.89Å; R674-T729 WeakPolarHBondContact CA-OG1 3.42Å; R674-T729 VanDerWaalsContact CB-OG1 3.29Å; R674-T729 WeakPolarHBondContact CB-OG1 3.19Å; R674-T729 WeakPolarHBondContact CG-OG1 3.13Å; R674-L732 HydrophobicContact CG-CD1 3.85Å
675E92.8Very high93.9Very high78 Ų7862.3 Ų62.336%0.36431%0.311SS..Hα-helixtrans-64.9-45179.4-69.3176.8151.900110.9K671 A677 A678 N679K671-E675 WeakPolarHBondContact CE-OE1 3.35Å; K671-E675 WeakPolarHBondContact CE-OE2 3.44Å; K671-E675 HydrophobicContact CG-CG 4.42Å; K671-E675 IonicContact NZ-OE1 3.05Å; K671-E675 PolarHBondContact O-N 2.64Å; E675-A677 PolarHBondContact O-N 2.96Å; E675-A678 PolarHBondContact O-N 2.97Å; E675-A678 VanDerWaalsContact O-N 3.1Å; E675-N679 VanDerWaalsContact O-CG 3.27Å; E675-N679 PolarHBondContact O-N 3.18Å; E675-N679 PolarHBondContact O-OD1 3.45Å
676K94Very high94.1Very high116 Ų11666.3 Ų66.350%0.50433%0.326SS..Hα-helixtrans-57.3-35.5171.7-178.9178166.7-163.20112.7Q672 E673 S680Q672-K676 WeakPolarHBondContact O-CB 3.3Å; Q672-K676 PolarHBondContact O-N 2.82Å; E673-K676 WeakPolarHBondContact OE1-CD 3.29Å; E673-K676 WeakPolarHBondContact OE1-CE 3.27Å; E673-K676 IonicContact OE1-NZ 3.84Å; E673-K676 PolarHBondContact OE1-NZ 3.44Å; K676-S680 VanDerWaalsContact O-CB 3.24Å; K676-S680 WeakPolarHBondContact O-CB 3.49Å; K676-S680 PolarHBondContact O-N 3.46Å; K676-S680 PolarHBondContact O-OG 3.27Å
677A96.1Very high94.3Very high3 Ų366.5 Ų66.53%0.02532%0.324CS..Hα-helixtrans-71.2-40.1174.600000112.8E673 R674 E675 S680 L681 T729 L732 K733E673-A677 VanDerWaalsContact O-CB 3.32Å; E673-A677 WeakPolarHBondContact O-CB 3.16Å; E673-A677 PolarHBondContact O-N 3.32Å; E673-A677 VanDerWaalsContact O-N 3.08Å; R674-A677 WeakPolarHBondContact O-CB 3.4Å; R674-A677 PolarHBondContact O-N 2.97Å; R674-A677 VanDerWaalsContact O-N 3.16Å; E675-A677 PolarHBondContact O-N 2.96Å; A677-S680 PolarHBondContact O-N 3.02Å; A677-L681 PolarHBondContact O-N 3.23Å; A677-L681 VanDerWaalsContact O-N 3.11Å; A677-T729 HydrophobicContact CB-CG2 4.16Å; A677-L732 HydrophobicContact CB-CB 3.91Å; A677-L732 HydrophobicContact CB-CD1 4.3Å; A677-K733 HydrophobicContact CB-CD 4.5Å; A677-K733 HydrophobicContact CB-CG 3.95Å
678A95.6Very high94.5Very high15 Ų1561.3 Ų61.312%0.12431%0.305CS..Hα-helixtrans-62.5-52.8174.300000111.1R674 E675 S680 L681 E682 L720 L732R674-A678 PolarHBondContact O-N 3.37Å; E675-A678 PolarHBondContact O-N 2.97Å; E675-A678 VanDerWaalsContact O-N 3.1Å; A678-S680 PolarHBondContact O-N 3.48Å; A678-L681 WeakPolarHBondContact O-CA 3.39Å; A678-L681 WeakPolarHBondContact O-CB 3.23Å; A678-L681 PolarHBondContact O-N 3.24Å; A678-E682 WeakPolarHBondContact O-CB 3.34Å; A678-E682 PolarHBondContact O-N 2.89Å; A678-L720 HydrophobicContact CB-CD1 4.46Å; A678-L732 HydrophobicContact CB-CD1 4.06Å; A678-L732 HydrophobicContact CB-CD2 4.3Å
679N96Very high94.8Very high96 Ų9661.9 Ų61.951%0.51331%0.306SS..Hα-helixtrans-61.3-32.9178.5-6018.7000111.8E675 L681 A683E675-N679 VanDerWaalsContact O-CG 3.27Å; E675-N679 PolarHBondContact O-N 3.18Å; E675-N679 PolarHBondContact O-OD1 3.45Å; N679-L681 VanDerWaalsContact C-N 3.33Å; N679-A683 WeakPolarHBondContact O-CB 3.37Å; N679-A683 PolarHBondContact O-N 3.47Å
680S97.1Very high95Very high50 Ų5062 Ų6235%0.3531%0.307SS..Hα-helixtrans-70.8-26.7174.4-63.30000113.6K676 A677 A678 F684K676-S680 VanDerWaalsContact O-CB 3.24Å; K676-S680 WeakPolarHBondContact O-CB 3.49Å; K676-S680 PolarHBondContact O-N 3.46Å; K676-S680 PolarHBondContact O-OG 3.27Å; A677-S680 PolarHBondContact O-N 3.02Å; A678-S680 PolarHBondContact O-N 3.48Å; S680-F684 WeakPolarHBondContact O-CB 3.4Å; S680-F684 PolarHBondContact O-N 2.85Å
681L97.1Very high95.2Very high0 Ų057.4 Ų57.40%029%0.285CS..Hα-helixtrans-79.4-48.9174.1173.158.6000110.3A677 A678 N679 F684 I685 W719 L720 L732 K735 L736 L739A677-L681 PolarHBondContact O-N 3.23Å; A677-L681 VanDerWaalsContact O-N 3.11Å; A678-L681 WeakPolarHBondContact O-CA 3.39Å; A678-L681 WeakPolarHBondContact O-CB 3.23Å; A678-L681 PolarHBondContact O-N 3.24Å; N679-L681 VanDerWaalsContact C-N 3.33Å; L681-F684 PolarHBondContact O-N 2.91Å; L681-I685 HydrophobicContact CD1-CD1 3.92Å; L681-I685 HydrophobicContact CD1-CG1 4.31Å; L681-I685 HydrophobicContact CG-CD1 3.98Å; L681-I685 WeakPolarHBondContact O-CG1 3.26Å; L681-I685 PolarHBondContact O-N 3.43Å; L681-W719 HydrophobicContact CD2-CZ3 4.05Å; L681-L720 HydrophobicContact CD2-CD1 4.23Å; L681-L720 HydrophobicContact CG-CD2 4.38Å; L681-L732 HydrophobicContact CD2-CD2 4.08Å; L681-K735 HydrophobicContact CD1-CB 4.2Å; L681-K735 HydrophobicContact CD2-CB 3.79Å; L681-L736 HydrophobicContact CB-CB 4.48Å; L681-L736 HydrophobicContact CD1-CB 4.16Å; L681-L739 HydrophobicContact CD1-CD1 3.65Å
682E96.6Very high95.4Very high88 Ų8854.3 Ų54.341%0.41127%0.272SS..Hα-helixtrans-55.1-53.8175.5-173.1179.4-162.200112.1A678 F684 I685 F686 L720A678-E682 WeakPolarHBondContact O-CB 3.34Å; A678-E682 PolarHBondContact O-N 2.89Å; E682-F684 VanDerWaalsContact C-N 3.28Å; E682-F684 PolarHBondContact O-N 3.41Å; E682-I685 WeakPolarHBondContact O-CB 3.44Å; E682-I685 PolarHBondContact O-N 3.02Å; E682-I685 VanDerWaalsContact O-N 3.08Å; E682-F686 HydrophobicContact CG-CD2 3.9Å; E682-F686 HydrophobicContact CG-CE2 3.59Å; E682-F686 WeakPolarHBondContact O-CD2 3.49Å; E682-F686 PolarHBondContact O-N 3.48Å; E682-L720 HydrophobicContact CB-CD2 3.84Å; E682-L720 HydrophobicContact CG-CD2 4.41Å
683A97.7Very high95.5Very high58 Ų5857.2 Ų57.248%0.47928%0.28SS..Hα-helixtrans-60.8-38178.200000111.9N679 I685 E687N679-A683 WeakPolarHBondContact O-CB 3.37Å; N679-A683 PolarHBondContact O-N 3.47Å; A683-I685 VanDerWaalsContact C-N 3.35Å; A683-E687 WeakPolarHBondContact O-CB 3.48Å; A683-E687 PolarHBondContact O-N 3.02Å
684F97.9Very high95.6Very high17 Ų1757 Ų578%0.07528%0.279CS..Hα-helixtrans-66.9-35.5175.8-174.1-88.6000112.4S680 L681 E682 T688 L713 L736 L739 R740 C743 F747S680-F684 WeakPolarHBondContact O-CB 3.4Å; S680-F684 PolarHBondContact O-N 2.85Å; L681-F684 PolarHBondContact O-N 2.91Å; E682-F684 VanDerWaalsContact C-N 3.28Å; E682-F684 PolarHBondContact O-N 3.41Å; F684-T688 WeakPolarHBondContact CE1-OG1 3.39Å; F684-T688 WeakPolarHBondContact O-CB 3.49Å; F684-T688 PolarHBondContact O-N 2.89Å; F684-T688 PolarHBondContact O-OG1 3.3Å; F684-L713 HydrophobicContact CE1-CD2 4.45Å; F684-L736 HydrophobicContact CB-CD1 3.52Å; F684-L736 HydrophobicContact CD1-CD1 3.95Å; F684-L736 HydrophobicContact CD2-CD1 4.04Å; F684-L736 HydrophobicContact CG-CD1 3.54Å; F684-L739 HydrophobicContact CD1-CB 4.05Å; F684-L739 HydrophobicContact CD1-CD1 4.48Å; F684-L739 HydrophobicContact CE1-CB 3.72Å; F684-R740 HydrophobicContact CD2-CG 4.03Å; F684-R740 HydrophobicContact CE1-CG 4.2Å; F684-R740 HydrophobicContact CE2-CG 3.48Å; F684-R740 VanDerWaalsContact CE2-CG 3.48Å; F684-R740 HydrophobicContact CZ-CB 4.34Å; F684-R740 HydrophobicContact CZ-CG 3.59Å; F684-C743 HydrophobicContact CZ-CB 4.32Å; F684-F747 AromaticContact CE2-CE2 3.84Å; F684-F747 HydrophobicContact CE2-CE2 3.84Å; F684-F747 HydrophobicContact CE2-CZ 4.38Å; F684-F747 AromaticContact CZ-CE2 3.82Å; F684-F747 HydrophobicContact CZ-CE2 3.82Å; F684-F747 HydrophobicContact CZ-CZ 4.13Å
685I97.5Very high95.6Very high1 Ų158.8 Ų58.81%0.00530%0.299CS..Hα-helixtrans-63.1-57.3176.3-72.6162.2000109.8L681 E682 A683 T688 Q689 L713 A716 L739L681-I685 HydrophobicContact CD1-CD1 3.92Å; L681-I685 HydrophobicContact CD1-CG1 4.31Å; L681-I685 HydrophobicContact CG-CD1 3.98Å; L681-I685 WeakPolarHBondContact O-CG1 3.26Å; L681-I685 PolarHBondContact O-N 3.43Å; E682-I685 WeakPolarHBondContact O-CB 3.44Å; E682-I685 PolarHBondContact O-N 3.02Å; E682-I685 VanDerWaalsContact O-N 3.08Å; A683-I685 VanDerWaalsContact C-N 3.35Å; I685-T688 PolarHBondContact O-N 2.78Å; I685-Q689 WeakPolarHBondContact O-CB 3.38Å; I685-Q689 WeakPolarHBondContact O-CG 3.44Å; I685-Q689 PolarHBondContact O-N 3.04Å; I685-L713 HydrophobicContact CG1-CD2 4.37Å; I685-L713 HydrophobicContact CG2-CB 4.39Å; I685-A716 HydrophobicContact CD1-CB 3.84Å; I685-A716 HydrophobicContact CG1-CB 4.39Å; I685-L739 HydrophobicContact CD1-CD1 4.35Å; I685-L739 HydrophobicContact CG1-CD1 3.88Å
686F95.8Very high95.7Very high112 Ų11258.7 Ų58.749%0.49130%0.298SS..Hα-helixtrans-65-44.8-178.3-68.3-57.9000113E682 T688 Q689 D690E682-F686 HydrophobicContact CG-CD2 3.9Å; E682-F686 HydrophobicContact CG-CE2 3.59Å; E682-F686 WeakPolarHBondContact O-CD2 3.49Å; E682-F686 PolarHBondContact O-N 3.48Å; F686-T688 VanDerWaalsContact C-N 3.28Å; F686-T688 PolarHBondContact O-N 3.03Å; F686-Q689 PolarHBondContact O-N 2.87Å; F686-D690 PolarHBondContact O-N 2.92Å; F686-D690 VanDerWaalsContact O-N 3.1Å
687E96.4Very high95.7Very high104 Ų10454.4 Ų54.449%0.48628%0.279SS..Hα-helixtrans-62.8-35.7178.9-165-151.4-16700111.5A683 K691A683-E687 WeakPolarHBondContact O-CB 3.48Å; A683-E687 PolarHBondContact O-N 3.02Å; E687-K691 HydrophobicContact CG-CD 4.36Å; E687-K691 WeakPolarHBondContact O-CB 3.41Å; E687-K691 VanDerWaalsContact O-CD 3.3Å; E687-K691 WeakPolarHBondContact O-CD 3.48Å; E687-K691 WeakPolarHBondContact O-CG 3.39Å; E687-K691 PolarHBondContact O-N 2.9Å; E687-K691 WeakPolarHBondContact OE1-CE 3.4Å; E687-K691 IonicContact OE1-NZ 3.93Å; E687-K691 PolarHBondContact OE1-NZ 3.09Å; E687-K691 IonicContact OE2-NZ 2.68Å; E687-K691 PolarHBondContact OE2-NZ 3.32Å
688T96.8Very high95.6Very high0 Ų058.2 Ų58.20%030%0.297CS..Hα-helixtrans-76.6-37.5176.5-520000112.1F684 I685 F686 D690 K691 L692 I709 L713 F747F684-T688 WeakPolarHBondContact CE1-OG1 3.39Å; F684-T688 WeakPolarHBondContact O-CB 3.49Å; F684-T688 PolarHBondContact O-N 2.89Å; F684-T688 PolarHBondContact O-OG1 3.3Å; I685-T688 PolarHBondContact O-N 2.78Å; F686-T688 VanDerWaalsContact C-N 3.28Å; F686-T688 PolarHBondContact O-N 3.03Å; T688-D690 PolarHBondContact O-N 3.4Å; T688-K691 PolarHBondContact O-N 3.29Å; T688-L692 WeakPolarHBondContact O-CG 3.47Å; T688-L692 PolarHBondContact O-N 2.97Å; T688-L692 VanDerWaalsContact O-N 3.11Å; T688-I709 HydrophobicContact CG2-CG2 4.45Å; T688-L713 HydrophobicContact CG2-CD1 3.63Å; T688-L713 HydrophobicContact CG2-CD2 4.33Å; T688-F747 HydrophobicContact CG2-CE1 4.06Å; T688-F747 HydrophobicContact CG2-CZ 3.77Å
689Q95.3Very high95.5Very high45 Ų4562.7 Ų62.721%0.2132%0.315CS..Hα-helixtrans-57.9-46.5175.6-80.8175.3-2700111.4I685 F686 Y693 L713I685-Q689 WeakPolarHBondContact O-CB 3.38Å; I685-Q689 WeakPolarHBondContact O-CG 3.44Å; I685-Q689 PolarHBondContact O-N 3.04Å; F686-Q689 PolarHBondContact O-N 2.87Å; Q689-Y693 VanDerWaalsContact O-CD2 3.24Å; Q689-Y693 WeakPolarHBondContact O-CD2 3.39Å; Q689-L713 HydrophobicContact CG-CB 4.06Å; Q689-L713 HydrophobicContact CG-CD1 3.96Å
690D95.1Very high95.5Very high99 Ų9958.1 Ų58.153%0.52929%0.291SS..Hα-helixtrans-61.6-50.2175179.481.3000111.8F686 T688 L692 Y693 Q694F686-D690 PolarHBondContact O-N 2.92Å; F686-D690 VanDerWaalsContact O-N 3.1Å; T688-D690 PolarHBondContact O-N 3.4Å; D690-L692 PolarHBondContact O-N 3.41Å; D690-L692 VanDerWaalsContact O-N 3.13Å; D690-Y693 PolarHBondContact O-N 3.49Å; D690-Q694 PolarHBondContact OD2-NE2 2.83Å
691K95.3Very high95.3Very high34 Ų3456.1 Ų56.115%0.14828%0.277CS..Hα-helixtrans-51.7-38.8179.3-79.9167.9-179.1173.20113.5E687 T688 Y693 Q694 Y697E687-K691 HydrophobicContact CG-CD 4.36Å; E687-K691 WeakPolarHBondContact O-CB 3.41Å; E687-K691 VanDerWaalsContact O-CD 3.3Å; E687-K691 WeakPolarHBondContact O-CD 3.48Å; E687-K691 WeakPolarHBondContact O-CG 3.39Å; E687-K691 PolarHBondContact O-N 2.9Å; E687-K691 WeakPolarHBondContact OE1-CE 3.4Å; E687-K691 IonicContact OE1-NZ 3.93Å; E687-K691 PolarHBondContact OE1-NZ 3.09Å; E687-K691 IonicContact OE2-NZ 2.68Å; E687-K691 PolarHBondContact OE2-NZ 3.32Å; T688-K691 PolarHBondContact O-N 3.29Å; K691-Y693 PolarHBondContact O-N 3.18Å; K691-Y693 VanDerWaalsContact O-N 3.09Å; K691-Q694 WeakPolarHBondContact O-CB 3.49Å; K691-Q694 PolarHBondContact O-N 2.64Å; K691-Y697 HydrophobicContact CB-CD1 4.05Å; K691-Y697 HydrophobicContact CB-CD2 4.27Å; K691-Y697 HydrophobicContact CB-CE1 3.81Å; K691-Y697 HydrophobicContact CB-CE2 4.03Å; K691-Y697 HydrophobicContact CB-CG 4.3Å; K691-Y697 HydrophobicContact CD-CE1 4.1Å; K691-Y697 WeakPolarHBondContact CD-OH 3.44Å; K691-Y697 HydrophobicContact CG-CE1 4.12Å; K691-Y697 HydrophobicContact CG-CE2 3.95Å; K691-Y697 WeakPolarHBondContact O-CB 3.06Å; K691-Y697 VanDerWaalsContact O-CD2 3.3Å; K691-Y697 WeakPolarHBondContact O-CD2 3.42Å
692L94.5Very high95.1Very high1 Ų159 Ų591%0.00529%0.294CS..THydrogen-bonded Turntrans-57.8-24.8-179.9-71.8170.7000113.9T688 D690 R706 I709 L713 L746T688-L692 WeakPolarHBondContact O-CG 3.47Å; T688-L692 PolarHBondContact O-N 2.97Å; T688-L692 VanDerWaalsContact O-N 3.11Å; D690-L692 PolarHBondContact O-N 3.41Å; D690-L692 VanDerWaalsContact O-N 3.13Å; L692-R706 HydrophobicContact CD2-CB 4.39Å; L692-R706 HydrophobicContact CD2-CG 4.14Å; L692-R706 WeakPolarHBondContact O-CD 3.49Å; L692-I709 HydrophobicContact CD1-CB 4.25Å; L692-I709 HydrophobicContact CD1-CG2 4Å; L692-I709 HydrophobicContact CD2-CB 4.27Å; L692-I709 HydrophobicContact CD2-CD1 4.31Å; L692-I709 HydrophobicContact CD2-CG2 4.18Å; L692-L713 HydrophobicContact CD1-CD1 3.97Å; L692-L746 HydrophobicContact CD2-CD2 3.65Å
693Y90.6Very high94.9Very high149 Ų14961 Ų6158%0.58430%0.303SS*.THydrogen-bonded Turntrans-99.5-3.6179.5-59.5-79.3000113.9Q689 D690 K691 Q698Q689-Y693 VanDerWaalsContact O-CD2 3.24Å; Q689-Y693 WeakPolarHBondContact O-CD2 3.39Å; D690-Y693 PolarHBondContact O-N 3.49Å; K691-Y693 PolarHBondContact O-N 3.18Å; K691-Y693 VanDerWaalsContact O-N 3.09Å; Y693-Q698 PolarHBondContact O-NE2 2.9Å; Y693-Q698 VanDerWaalsContact O-NE2 3.16Å
694Q95.2Very high94.7Very high66 Ų6664.3 Ų64.331%0.30831%0.309SS..SBendtrans-75142.4175.4-62.8179.1900111.1D690 K691 E696 Y697 Q698D690-Q694 PolarHBondContact OD2-NE2 2.83Å; K691-Q694 WeakPolarHBondContact O-CB 3.49Å; K691-Q694 PolarHBondContact O-N 2.64Å; Q694-E696 VanDerWaalsContact C-N 3.31Å; Q694-E696 PolarHBondContact O-N 2.71Å; Q694-Y697 HydrophobicContact CB-CD2 3.92Å; Q694-Y697 PolarHBondContact O-N 2.94Å; Q694-Q698 PolarHBondContact O-N 2.9Å
695P94.5Very high94.5Very high102 Ų10266.5 Ų66.566%0.66232%0.319SS*.Hα-helixtrans-55.3-40.2-175-28.935.8000114.7Y697 Q698 E699P695-Y697 PolarHBondContact O-N 3.1Å; P695-Q698 PolarHBondContact O-N 3.26Å; P695-E699 PolarHBondContact O-N 2.99Å
696E93.9Very high94.3Very high76 Ų7668.4 Ų68.436%0.35533%0.327SS..Hα-helixtrans-58.1-32.1178.4-62.2-178.3-137.300112.9Q694 V750 K754Q694-E696 VanDerWaalsContact C-N 3.31Å; Q694-E696 PolarHBondContact O-N 2.71Å; E696-V750 HydrophobicContact CB-CG1 4.08Å; E696-K754 IonicContact OE1-NZ 3.82Å; E696-K754 PolarHBondContact OE1-NZ 2.78Å; E696-K754 IonicContact OE2-NZ 3.24Å; E696-K754 PolarHBondContact OE2-NZ 2.88Å
697Y95.3Very high94.2Very high26 Ų2669.4 Ų69.410%0.10233%0.333CS..Hα-helixtrans-88.8-34.3179.8-67.5-104.8000111.5K691 Q694 P695 V700 S701 L746 F747 V750K691-Y697 HydrophobicContact CB-CD1 4.05Å; K691-Y697 HydrophobicContact CB-CD2 4.27Å; K691-Y697 HydrophobicContact CB-CE1 3.81Å; K691-Y697 HydrophobicContact CB-CE2 4.03Å; K691-Y697 HydrophobicContact CB-CG 4.3Å; K691-Y697 HydrophobicContact CD-CE1 4.1Å; K691-Y697 WeakPolarHBondContact CD-OH 3.44Å; K691-Y697 HydrophobicContact CG-CE1 4.12Å; K691-Y697 HydrophobicContact CG-CE2 3.95Å; K691-Y697 WeakPolarHBondContact O-CB 3.06Å; K691-Y697 VanDerWaalsContact O-CD2 3.3Å; K691-Y697 WeakPolarHBondContact O-CD2 3.42Å; Q694-Y697 HydrophobicContact CB-CD2 3.92Å; Q694-Y697 PolarHBondContact O-N 2.94Å; P695-Y697 PolarHBondContact O-N 3.1Å; Y697-V700 WeakPolarHBondContact O-CG2 3.46Å; Y697-V700 PolarHBondContact O-N 3.31Å; Y697-S701 WeakPolarHBondContact O-CB 3.35Å; Y697-S701 PolarHBondContact O-N 2.98Å; Y697-S701 PolarHBondContact O-OG 3.32Å; Y697-L746 HydrophobicContact CD1-CD1 4.4Å; Y697-L746 HydrophobicContact CD1-CD2 4.18Å; Y697-L746 HydrophobicContact CD1-CG 4.1Å; Y697-F747 HydrophobicContact CD1-CD1 4.45Å; Y697-F747 AromaticContact CE1-CD1 3.76Å; Y697-F747 HydrophobicContact CE1-CD1 3.76Å; Y697-F747 AromaticContact CE1-CE1 3.91Å; Y697-F747 HydrophobicContact CE1-CE1 3.91Å; Y697-V750 HydrophobicContact CD1-CG2 3.7Å; Y697-V750 HydrophobicContact CD2-CG1 4.45Å; Y697-V750 HydrophobicContact CD2-CG2 4.26Å; Y697-V750 HydrophobicContact CE1-CB 4.45Å; Y697-V750 HydrophobicContact CE1-CG2 3.89Å; Y697-V750 HydrophobicContact CE2-CG1 4.07Å; Y697-V750 HydrophobicContact CE2-CG2 4.45Å; Y697-V750 HydrophobicContact CG-CG2 3.88Å
698Q94.2Very high94.2Very high83 Ų8369.8 Ų69.839%0.38833%0.334SS..Hα-helixtrans-63.7-39.9174.4-70.2-179-15.200112Y693 Q694 P695 V700 S701 R706Y693-Q698 PolarHBondContact O-NE2 2.9Å; Y693-Q698 VanDerWaalsContact O-NE2 3.16Å; Q694-Q698 PolarHBondContact O-N 2.9Å; P695-Q698 PolarHBondContact O-N 3.26Å; Q698-V700 VanDerWaalsContact C-N 3.26Å; Q698-V700 PolarHBondContact O-N 2.8Å; Q698-S701 PolarHBondContact O-N 3Å; Q698-R706 PolarHBondContact O-NH1 2.83Å
699E93.2Very high94.2Very high110 Ų11069.9 Ų69.951%0.51434%0.335SS..Hα-helixtrans-56.6-38.8176.7-168.5-163123.200112.4P695 R753 A818P695-E699 PolarHBondContact O-N 2.99Å; E699-R753 WeakPolarHBondContact OE1-CD 3.48Å; E699-R753 IonicContact OE1-CZ 2.95Å; E699-R753 IonicContact OE1-NE 2.91Å; E699-R753 IonicContact OE1-NH1 2.69Å; E699-R753 PolarHBondContact OE1-NH1 3.45Å; E699-A818 HydrophobicContact CG-CB 4.23Å; E699-A818 VanDerWaalsContact O-CB 3.24Å; E699-A818 WeakPolarHBondContact O-CB 3.39Å
700V94.6Very high94.2Very high0 Ų068.8 Ų68.80%033%0.332CS..THydrogen-bonded Turntrans-99.810.6-173.9-58.10000114.4Y697 Q698 L746 R749 V750 R753 A818Y697-V700 WeakPolarHBondContact O-CG2 3.46Å; Y697-V700 PolarHBondContact O-N 3.31Å; Q698-V700 VanDerWaalsContact C-N 3.26Å; Q698-V700 PolarHBondContact O-N 2.8Å; V700-L746 HydrophobicContact CG2-CD1 3.62Å; V700-R749 HydrophobicContact CB-CB 3.83Å; V700-R749 HydrophobicContact CG1-CB 4.02Å; V700-R749 HydrophobicContact CG2-CB 4.08Å; V700-R749 PolarHBondContact O-NE 2.69Å; V700-R749 PolarHBondContact O-NH1 2.7Å; V700-R749 VanDerWaalsContact O-NH1 3.11Å; V700-R749 PolarHBondContact O-NH2 3.26Å; V700-R749 VanDerWaalsContact O-NH2 3.12Å; V700-V750 HydrophobicContact CG2-CG2 3.51Å; V700-R753 VanDerWaalsContact CG1-CD 3.43Å; V700-A818 WeakPolarHBondContact CA-O 3.37Å; V700-A818 WeakPolarHBondContact CB-O 3.31Å
701S94.5Very high94.3Very high8 Ų866 Ų666%0.05633%0.327CS..  trans-134.2150.2-178.955.80000112.8Y697 Q698 R706Y697-S701 WeakPolarHBondContact O-CB 3.35Å; Y697-S701 PolarHBondContact O-N 2.98Å; Y697-S701 PolarHBondContact O-OG 3.32Å; Q698-S701 PolarHBondContact O-N 3Å; S701-R706 PolarHBondContact O-NH1 2.88Å; S701-R706 WeakPolarHBondContact OG-CD 3.28Å; S701-R706 VanDerWaalsContact OG-CG 3.32Å; S701-R706 WeakPolarHBondContact OG-CG 3.44Å; S701-R706 PolarHBondContact OG-NH1 2.81Å
702T93.3Very high94.4Very high59 Ų5969.9 Ų69.936%0.36234%0.344SS..  trans-82.4164.9165.179.30000109.8E704 Q705 R706 T819T702-E704 WeakPolarHBondContact CB-OE2 3.31Å; T702-E704 PolarHBondContact OG1-OE2 3.17Å; T702-Q705 PolarHBondContact O-N 2.87Å; T702-Q705 PolarHBondContact OG1-N 2.86Å; T702-R706 PolarHBondContact O-N 2.84Å; T702-R706 VanDerWaalsContact O-N 3.15Å; T702-R706 PolarHBondContact O-NH1 2.76Å; T702-T819 HydrophobicContact CG2-CG2 4.01Å
703E91.7Very high94.5Very high131 Ų13169.9 Ų69.961%0.61234%0.344SS*.Hα-helixtrans-66-43.9179.7-170.2151.7-133.900111.4Q705 R706 E707E703-Q705 VanDerWaalsContact C-N 3.28Å; E703-Q705 PolarHBondContact O-N 3.36Å; E703-R706 WeakPolarHBondContact O-CA 3.41Å; E703-R706 WeakPolarHBondContact O-CB 3.34Å; E703-R706 PolarHBondContact O-N 3Å; E703-E707 WeakPolarHBondContact O-CG 3.42Å; E703-E707 PolarHBondContact O-N 3.22Å
704E92.9Very high94.8Very high128 Ų12865 Ų6560%0.59833%0.331SS*.Hα-helixtrans-62.4-35.2177.5-42.785.416400111.7T702 E707 E708T702-E704 WeakPolarHBondContact CB-OE2 3.31Å; T702-E704 PolarHBondContact OG1-OE2 3.17Å; E704-E707 PolarHBondContact O-N 2.64Å; E704-E708 PolarHBondContact O-N 2.78Å
705Q93Very high94.9Very high62 Ų6264.8 Ų64.829%0.2934%0.341SS..Hα-helixtrans-68.2-36.7173.8176.8165.467.100111.9T702 E703 I709 R749T702-Q705 PolarHBondContact O-N 2.87Å; T702-Q705 PolarHBondContact OG1-N 2.86Å; E703-Q705 VanDerWaalsContact C-N 3.28Å; E703-Q705 PolarHBondContact O-N 3.36Å; Q705-I709 HydrophobicContact CG-CD1 4.01Å; Q705-I709 WeakPolarHBondContact O-CD1 3.39Å; Q705-I709 WeakPolarHBondContact O-CG1 3.27Å; Q705-I709 PolarHBondContact O-N 3.27Å; Q705-R749 VanDerWaalsContact OE1-NH1 3.08Å
706R94.3Very high95Very high42 Ų4260.3 Ų60.316%0.15831%0.312CS..Hα-helixtrans-69.4-40.6174.1-68.3-174.3-68.1-88.83.8111.2L692 Q698 S701 T702 E703 I709 S710L692-R706 HydrophobicContact CD2-CB 4.39Å; L692-R706 HydrophobicContact CD2-CG 4.14Å; L692-R706 WeakPolarHBondContact O-CD 3.49Å; Q698-R706 PolarHBondContact O-NH1 2.83Å; S701-R706 PolarHBondContact O-NH1 2.88Å; S701-R706 WeakPolarHBondContact OG-CD 3.28Å; S701-R706 VanDerWaalsContact OG-CG 3.32Å; S701-R706 WeakPolarHBondContact OG-CG 3.44Å; S701-R706 PolarHBondContact OG-NH1 2.81Å; T702-R706 PolarHBondContact O-N 2.84Å; T702-R706 VanDerWaalsContact O-N 3.15Å; T702-R706 PolarHBondContact O-NH1 2.76Å; E703-R706 WeakPolarHBondContact O-CA 3.41Å; E703-R706 WeakPolarHBondContact O-CB 3.34Å; E703-R706 PolarHBondContact O-N 3Å; R706-I709 PolarHBondContact O-N 2.83Å; R706-S710 WeakPolarHBondContact O-CB 3.4Å; R706-S710 PolarHBondContact O-N 3.35Å
707E94.4Very high95.1Very high133 Ų13357.6 Ų57.662%0.62130%0.302SS*.Hα-helixtrans-63.4-44.2175.6-70.8-171.4148.700112.4E703 E704 I709 S710 G711E703-E707 WeakPolarHBondContact O-CG 3.42Å; E703-E707 PolarHBondContact O-N 3.22Å; E704-E707 PolarHBondContact O-N 2.64Å; E707-I709 PolarHBondContact O-N 3.21Å; E707-S710 PolarHBondContact O-N 3.32Å; E707-G711 PolarHBondContact O-N 2.74Å
708E95.5Very high95.1Very high111 Ų11159.9 Ų59.952%0.51932%0.319SS..Hα-helixtrans-59-49.7175.8-173.3-173.4-175.700110.8E704 G711 K712E704-E708 PolarHBondContact O-N 2.78Å; E708-G711 PolarHBondContact O-N 2.68Å; E708-K712 VanDerWaalsContact O-CG 3.28Å; E708-K712 WeakPolarHBondContact O-CG 3.48Å; E708-K712 PolarHBondContact O-N 2.86Å
709I96.5Very high95.2Very high3 Ų357.7 Ų57.72%0.01531%0.307CS..Hα-helixtrans-64.1-48.2-179.6-61.5167.9000110.1T688 L692 Q705 R706 E707 G711 K712 L713 L742 L746T688-I709 HydrophobicContact CG2-CG2 4.45Å; L692-I709 HydrophobicContact CD1-CB 4.25Å; L692-I709 HydrophobicContact CD1-CG2 4Å; L692-I709 HydrophobicContact CD2-CB 4.27Å; L692-I709 HydrophobicContact CD2-CD1 4.31Å; L692-I709 HydrophobicContact CD2-CG2 4.18Å; Q705-I709 HydrophobicContact CG-CD1 4.01Å; Q705-I709 WeakPolarHBondContact O-CD1 3.39Å; Q705-I709 WeakPolarHBondContact O-CG1 3.27Å; Q705-I709 PolarHBondContact O-N 3.27Å; R706-I709 PolarHBondContact O-N 2.83Å; E707-I709 PolarHBondContact O-N 3.21Å; I709-G711 VanDerWaalsContact C-N 3.34Å; I709-G711 PolarHBondContact O-N 3.42Å; I709-K712 PolarHBondContact O-N 2.89Å; I709-K712 VanDerWaalsContact O-N 3.12Å; I709-L713 HydrophobicContact CG2-CD1 3.78Å; I709-L713 HydrophobicContact CG2-CG 4.19Å; I709-L713 VanDerWaalsContact O-CG 3.26Å; I709-L713 WeakPolarHBondContact O-CG 3.45Å; I709-L713 PolarHBondContact O-N 3.47Å; I709-L742 HydrophobicContact CB-CD2 4.47Å; I709-L742 HydrophobicContact CG1-CD2 4.16Å; I709-L742 HydrophobicContact CG1-CG 4.14Å; I709-L742 HydrophobicContact CG2-CD2 4.45Å; I709-L746 HydrophobicContact CD1-CD2 3.92Å
710S96.4Very high95.2Very high22 Ų2253.7 Ų53.715%0.15429%0.289CS..Hα-helixtrans-59.5-41.9179-170.80000112.3R706 E707 K712 L713 S714R706-S710 WeakPolarHBondContact O-CB 3.4Å; R706-S710 PolarHBondContact O-N 3.35Å; E707-S710 PolarHBondContact O-N 3.32Å; S710-K712 PolarHBondContact O-N 2.78Å; S710-L713 PolarHBondContact O-N 3.35Å; S710-S714 WeakPolarHBondContact O-CB 3.26Å; S710-S714 PolarHBondContact O-N 2.88Å; S710-S714 PolarHBondContact O-OG 3.3Å
711G96.8Very high95.1Very high40 Ų4059.5 Ų59.541%0.41232%0.316SS..Hα-helixtrans-63.1-39.4173.800000113.3E707 E708 I709 A715E707-G711 PolarHBondContact O-N 2.74Å; E708-G711 PolarHBondContact O-N 2.68Å; I709-G711 VanDerWaalsContact C-N 3.34Å; I709-G711 PolarHBondContact O-N 3.42Å; G711-A715 WeakPolarHBondContact O-CB 3.43Å; G711-A715 PolarHBondContact O-N 3.48Å
712K97.4Very high94.9Very high116 Ų11665.3 Ų65.350%0.50435%0.347SS..Hα-helixtrans-69.2-38.7175-67.5-66.2-178.4-172.90112.9E708 I709 S710 A716 L739 L742E708-K712 VanDerWaalsContact O-CG 3.28Å; E708-K712 WeakPolarHBondContact O-CG 3.48Å; E708-K712 PolarHBondContact O-N 2.86Å; I709-K712 PolarHBondContact O-N 2.89Å; I709-K712 VanDerWaalsContact O-N 3.12Å; S710-K712 PolarHBondContact O-N 2.78Å; K712-A716 WeakPolarHBondContact O-CB 3.41Å; K712-A716 PolarHBondContact O-N 2.85Å; K712-A716 VanDerWaalsContact O-N 3.08Å; K712-L739 HydrophobicContact CB-CD2 4.29Å; K712-L742 HydrophobicContact CB-CD2 3.71Å; K712-L742 HydrophobicContact CG-CD2 3.75Å
713L97.4Very high94.7Very high0 Ų068.2 Ų68.20%036%0.356CS..Hα-helixtrans-65.3-44.5174.6-66.1167.4000110.8F684 I685 T688 Q689 L692 I709 S710 A716 S717 L739F684-L713 HydrophobicContact CE1-CD2 4.45Å; I685-L713 HydrophobicContact CG1-CD2 4.37Å; I685-L713 HydrophobicContact CG2-CB 4.39Å; T688-L713 HydrophobicContact CG2-CD1 3.63Å; T688-L713 HydrophobicContact CG2-CD2 4.33Å; Q689-L713 HydrophobicContact CG-CB 4.06Å; Q689-L713 HydrophobicContact CG-CD1 3.96Å; L692-L713 HydrophobicContact CD1-CD1 3.97Å; I709-L713 HydrophobicContact CG2-CD1 3.78Å; I709-L713 HydrophobicContact CG2-CG 4.19Å; I709-L713 VanDerWaalsContact O-CG 3.26Å; I709-L713 WeakPolarHBondContact O-CG 3.45Å; I709-L713 PolarHBondContact O-N 3.47Å; S710-L713 PolarHBondContact O-N 3.35Å; L713-A716 WeakPolarHBondContact O-CB 3.49Å; L713-A716 PolarHBondContact O-N 2.76Å; L713-A716 VanDerWaalsContact O-N 3.14Å; L713-S717 PolarHBondContact O-N 3.09Å; L713-L739 HydrophobicContact CD2-CD1 4.16Å; L713-L739 HydrophobicContact CD2-CD2 4.08Å
714S96.6Very high94.3Very high47 Ų4762.2 Ų62.233%0.32933%0.329SS..Hα-helixtrans-64-45.5179.1-54.90000111.6S710 A716 S717 T718S710-S714 WeakPolarHBondContact O-CB 3.26Å; S710-S714 PolarHBondContact O-N 2.88Å; S710-S714 PolarHBondContact O-OG 3.3Å; S714-A716 PolarHBondContact O-N 2.82Å; S714-S717 WeakPolarHBondContact O-CB 3.45Å; S714-S717 PolarHBondContact O-N 2.84Å; S714-S717 VanDerWaalsContact O-N 3.09Å; S714-T718 PolarHBondContact O-N 3.29Å; S714-T718 PolarHBondContact O-OG1 2.84Å
715A96.5Very high93.8Very high62 Ų6261.4 Ų61.451%0.51233%0.333SS..Hα-helixtrans-62.6-29.417400000113G711 W719G711-A715 WeakPolarHBondContact O-CB 3.43Å; G711-A715 PolarHBondContact O-N 3.48Å; A715-W719 VanDerWaalsContact O-CB 3.3Å; A715-W719 WeakPolarHBondContact O-CB 3.36Å; A715-W719 PolarHBondContact O-N 3.37Å; A715-W719 VanDerWaalsContact O-N 3.13Å
716A96.2Very high93.5Very high7 Ų761.9 Ų61.96%0.05835%0.354CS..Hα-helixtrans-76-30.1173.200000113I685 K712 L713 S714 L720 L739I685-A716 HydrophobicContact CD1-CB 3.84Å; I685-A716 HydrophobicContact CG1-CB 4.39Å; K712-A716 WeakPolarHBondContact O-CB 3.41Å; K712-A716 PolarHBondContact O-N 2.85Å; K712-A716 VanDerWaalsContact O-N 3.08Å; L713-A716 WeakPolarHBondContact O-CB 3.49Å; L713-A716 PolarHBondContact O-N 2.76Å; L713-A716 VanDerWaalsContact O-N 3.14Å; S714-A716 PolarHBondContact O-N 2.82Å; A716-L720 VanDerWaalsContact O-CB 3.31Å; A716-L720 WeakPolarHBondContact O-CB 3.32Å; A716-L720 PolarHBondContact O-N 3.37Å; A716-L739 HydrophobicContact CB-CD1 3.8Å; A716-L739 HydrophobicContact CB-CD2 4.34Å
717S95.9Very high93.3Very high19 Ų1960 Ų6013%0.13335%0.347CS..Hα-helixtrans-64.8-55.3171.3-162.30000110.5L713 S714 W719 L720 E721L713-S717 PolarHBondContact O-N 3.09Å; S714-S717 WeakPolarHBondContact O-CB 3.45Å; S714-S717 PolarHBondContact O-N 2.84Å; S714-S717 VanDerWaalsContact O-N 3.09Å; S717-W719 VanDerWaalsContact C-N 3.26Å; S717-W719 PolarHBondContact O-N 2.86Å; S717-L720 WeakPolarHBondContact O-CA 3.49Å; S717-L720 WeakPolarHBondContact O-CB 3.48Å; S717-L720 PolarHBondContact O-N 3.42Å; S717-E721 WeakPolarHBondContact CB-OE1 3.11Å; S717-E721 WeakPolarHBondContact O-CG 3.29Å; S717-E721 PolarHBondContact O-N 3.33Å; S717-E721 PolarHBondContact OG-OE1 3.15Å
718T95.7Very high93.3Very high74 Ų7457.1 Ų57.145%0.45434%0.339SS..Hα-helixtrans-57-40.9178.1-49.90000111.7S714 L720 E721 D722S714-T718 PolarHBondContact O-N 3.29Å; S714-T718 PolarHBondContact O-OG1 2.84Å; T718-L720 PolarHBondContact O-N 2.88Å; T718-E721 PolarHBondContact O-N 3.41Å; T718-D722 WeakPolarHBondContact O-CB 3.42Å; T718-D722 PolarHBondContact O-N 3.15Å
719W96Very high93.3Very high37 Ų3753.5 Ų53.514%0.1432%0.324CS..Hα-helixtrans-63.7-37.5173.5177.182.4000113.3L681 A715 S717 E721 E723 G724 A727 M731 L732 K735L681-W719 HydrophobicContact CD2-CZ3 4.05Å; A715-W719 VanDerWaalsContact O-CB 3.3Å; A715-W719 WeakPolarHBondContact O-CB 3.36Å; A715-W719 PolarHBondContact O-N 3.37Å; A715-W719 VanDerWaalsContact O-N 3.13Å; S717-W719 VanDerWaalsContact C-N 3.26Å; S717-W719 PolarHBondContact O-N 2.86Å; W719-E721 VanDerWaalsContact C-N 3.34Å; W719-E723 HydrophobicContact CG-CB 4.45Å; W719-E723 PolarHBondContact NE1-OE2 2.94Å; W719-E723 CarbonylContact O-C 3.52Å; W719-E723 WeakPolarHBondContact O-CA 3.39Å; W719-E723 WeakPolarHBondContact O-CB 3.25Å; W719-E723 PolarHBondContact O-N 3.38Å; W719-G724 PolarHBondContact O-N 2.9Å; W719-A727 HydrophobicContact CH2-CB 3.57Å; W719-A727 HydrophobicContact CZ2-CB 3.9Å; W719-M731 HydrophobicContact CZ2-CE 4.26Å; W719-L732 HydrophobicContact CH2-CD2 4.15Å; W719-L732 HydrophobicContact CZ3-CD2 4.04Å; W719-K735 HydrophobicContact CE3-CD 4.28Å; W719-K735 HydrophobicContact CE3-CG 4.13Å; W719-K735 HydrophobicContact CH2-CG 4.01Å; W719-K735 HydrophobicContact CZ3-CB 4.42Å; W719-K735 HydrophobicContact CZ3-CD 4.44Å; W719-K735 HydrophobicContact CZ3-CG 3.78Å
720L93.9Very high93.3Very high26 Ų2657.6 Ų57.614%0.13635%0.349CS..Hα-helixtrans-69-34.5177.2-17661.5000111.9A678 L681 E682 A716 S717 T718 G724 L732A678-L720 HydrophobicContact CB-CD1 4.46Å; L681-L720 HydrophobicContact CD2-CD1 4.23Å; L681-L720 HydrophobicContact CG-CD2 4.38Å; E682-L720 HydrophobicContact CB-CD2 3.84Å; E682-L720 HydrophobicContact CG-CD2 4.41Å; A716-L720 VanDerWaalsContact O-CB 3.31Å; A716-L720 WeakPolarHBondContact O-CB 3.32Å; A716-L720 PolarHBondContact O-N 3.37Å; S717-L720 WeakPolarHBondContact O-CA 3.49Å; S717-L720 WeakPolarHBondContact O-CB 3.48Å; S717-L720 PolarHBondContact O-N 3.42Å; T718-L720 PolarHBondContact O-N 2.88Å; L720-G724 VanDerWaalsContact O-CA 3.24Å; L720-G724 WeakPolarHBondContact O-CA 3.47Å; L720-G724 PolarHBondContact O-N 2.93Å; L720-L732 HydrophobicContact CD1-CD2 3.79Å
721E91.3Very high93.3Very high123 Ų12360.2 Ų60.258%0.57536%0.36SS*.Hα-helixtrans-71.2-49.8175.9-67.7159.3-124.400111.9S717 T718 W719S717-E721 WeakPolarHBondContact CB-OE1 3.11Å; S717-E721 WeakPolarHBondContact O-CG 3.29Å; S717-E721 PolarHBondContact O-N 3.33Å; S717-E721 PolarHBondContact OG-OE1 3.15Å; T718-E721 PolarHBondContact O-N 3.41Å; W719-E721 VanDerWaalsContact C-N 3.34Å
722D90.8Very high93.3Very high130 Ų13058.3 Ų58.370%0.69534%0.341SS*.Hα-helixtrans-81.4-51.4-175.8-74.9-34.5000113.6T718T718-D722 WeakPolarHBondContact O-CB 3.42Å; T718-D722 PolarHBondContact O-N 3.15Å
723E90.1Very high93.2Very high120 Ų12057.2 Ų57.256%0.56134%0.336SS*.THydrogen-bonded Turntrans-102.9-29.2-174.4-68.9-178.8-138.700113W719 V725 G726 A727W719-E723 HydrophobicContact CG-CB 4.45Å; W719-E723 PolarHBondContact NE1-OE2 2.94Å; W719-E723 CarbonylContact O-C 3.52Å; W719-E723 WeakPolarHBondContact O-CA 3.39Å; W719-E723 WeakPolarHBondContact O-CB 3.25Å; W719-E723 PolarHBondContact O-N 3.38Å; E723-V725 PolarHBondContact O-N 3.34Å; E723-V725 VanDerWaalsContact O-N 3.12Å; E723-G726 PolarHBondContact O-N 3.34Å; E723-A727 PolarHBondContact O-N 3Å
724G82.3Confident93.2Very high4 Ų462.6 Ų62.64%0.04136%0.361CS..THydrogen-bonded Turntrans-60-25.4-171.900000115R674 W719 L720 G726 A727R674-G724 PolarHBondContact NH1-O 3.47Å; R674-G724 VanDerWaalsContact NH1-O 3.09Å; W719-G724 PolarHBondContact O-N 2.9Å; L720-G724 VanDerWaalsContact O-CA 3.24Å; L720-G724 WeakPolarHBondContact O-CA 3.47Å; L720-G724 PolarHBondContact O-N 2.93Å; G724-G726 VanDerWaalsContact C-N 3.26Å; G724-G726 PolarHBondContact O-N 3.43Å; G724-A727 PolarHBondContact O-N 3.49Å; G724-A727 VanDerWaalsContact O-N 3.16Å
725V82.4Confident93.2Very high112 Ų11263.4 Ų63.468%0.67936%0.358SS*.THydrogen-bonded Turntrans-55-42.9171.5-177.60000111.1R674 E723R674-V725 PolarHBondContact NH1-O 3.47Å; R674-V725 VanDerWaalsContact NH1-O 3.08Å; R674-V725 PolarHBondContact NH2-O 3.23Å; E723-V725 PolarHBondContact O-N 3.34Å; E723-V725 VanDerWaalsContact O-N 3.12Å
726G86.3Confident93.3Very high71 Ų7161.1 Ų61.173%0.73234%0.338SS*.THydrogen-bonded Turntrans-91.6-7.2177.600000115E723 G724E723-G726 PolarHBondContact O-N 3.34Å; G724-G726 VanDerWaalsContact C-N 3.26Å; G724-G726 PolarHBondContact O-N 3.43Å
727A91.7Very high93.4Very high3 Ų363.4 Ų63.43%0.02536%0.357CS..  trans-68.1142.8-17400000113.3R674 W719 E723 G724 M731 L732R674-A727 WeakPolarHBondContact CD-O 2.99Å; R674-A727 PolarHBondContact NH1-O 2.89Å; W719-A727 HydrophobicContact CH2-CB 3.57Å; W719-A727 HydrophobicContact CZ2-CB 3.9Å; E723-A727 PolarHBondContact O-N 3Å; G724-A727 PolarHBondContact O-N 3.49Å; G724-A727 VanDerWaalsContact O-N 3.16Å; A727-M731 HydrophobicContact CB-CB 4.46Å; A727-M731 HydrophobicContact CB-CE 4.41Å; A727-L732 HydrophobicContact CB-CD2 4.09Å; A727-L732 HydrophobicContact CB-CG 4.1Å
728T94.4Very high93.4Very high72 Ų7267.9 Ų67.944%0.44238%0.376SS..  trans-76.6157.6176.969.60000112V730 M731 L732T728-V730 PolarHBondContact O-N 3.28Å; T728-V730 VanDerWaalsContact O-N 3.11Å; T728-M731 HydrophobicContact CG2-SD 4.02Å; T728-M731 PolarHBondContact O-N 3.3Å; T728-M731 VanDerWaalsContact O-N 3.1Å; T728-M731 VanDerWaalsContact OG1-CG 3.31Å; T728-M731 WeakPolarHBondContact OG1-CG 3.41Å; T728-M731 PolarHBondContact OG1-N 3.33Å; T728-M731 PolarHBondContact OG1-SD 2.91Å; T728-M731 VanDerWaalsContact OG1-SD 3.36Å; T728-L732 WeakPolarHBondContact O-CG 3.24Å; T728-L732 PolarHBondContact O-N 3.26Å
729T94.4Very high93.5Very high35 Ų3564.9 Ų64.922%0.21536%0.357CS..Hα-helixtrans-55.4-28.5175.3-45.20000113.1E673 R674 A677 K733E673-T729 HydrophobicContact CB-CG2 4.39Å; E673-T729 WeakPolarHBondContact O-CG2 3.36Å; R674-T729 WeakPolarHBondContact CA-OG1 3.42Å; R674-T729 VanDerWaalsContact CB-OG1 3.29Å; R674-T729 WeakPolarHBondContact CB-OG1 3.19Å; R674-T729 WeakPolarHBondContact CG-OG1 3.13Å; A677-T729 HydrophobicContact CB-CG2 4.16Å; T729-K733 HydrophobicContact CG2-CD 4.16Å; T729-K733 WeakPolarHBondContact O-CB 3.46Å; T729-K733 WeakPolarHBondContact O-CD 3.36Å; T729-K733 VanDerWaalsContact O-CG 3.24Å; T729-K733 WeakPolarHBondContact O-CG 3.47Å; T729-K733 PolarHBondContact O-N 3.44Å
730V96.3Very high93.5Very high89 Ų8969.5 Ų69.554%0.53937%0.374SS..Hα-helixtrans-71.1-53.7175.1-1800000110.2T728 L732 K733 E734T728-V730 PolarHBondContact O-N 3.28Å; T728-V730 VanDerWaalsContact O-N 3.11Å; V730-L732 VanDerWaalsContact C-N 3.29Å; V730-L732 PolarHBondContact O-N 2.91Å; V730-K733 CarbonylContact O-C 3.55Å; V730-K733 PolarHBondContact O-N 2.9Å; V730-E734 HydrophobicContact CG1-CG 4.24Å; V730-E734 WeakPolarHBondContact O-CG 3.44Å; V730-E734 PolarHBondContact O-N 2.8Å
731M95.9Very high93.7Very high78 Ų7876.2 Ų76.238%0.38440%0.402SS..Hα-helixtrans-57.4-40.8-179.6-65.3159.371.900112.3W719 A727 T728 E734 K735W719-M731 HydrophobicContact CZ2-CE 4.26Å; A727-M731 HydrophobicContact CB-CB 4.46Å; A727-M731 HydrophobicContact CB-CE 4.41Å; T728-M731 HydrophobicContact CG2-SD 4.02Å; T728-M731 PolarHBondContact O-N 3.3Å; T728-M731 VanDerWaalsContact O-N 3.1Å; T728-M731 VanDerWaalsContact OG1-CG 3.31Å; T728-M731 WeakPolarHBondContact OG1-CG 3.41Å; T728-M731 PolarHBondContact OG1-N 3.33Å; T728-M731 PolarHBondContact OG1-SD 2.91Å; T728-M731 VanDerWaalsContact OG1-SD 3.36Å; M731-E734 PolarHBondContact O-N 3.1Å; M731-K735 WeakPolarHBondContact O-CB 3.45Å; M731-K735 WeakPolarHBondContact O-CG 3.32Å; M731-K735 PolarHBondContact O-N 3.36Å
732L97Very high93.9Very high0 Ų073.2 Ų73.20%039%0.39CS..Hα-helixtrans-63.8-43.8176.2-66.6166000111.9R674 A677 A678 L681 W719 L720 A727 T728 V730 L736R674-L732 HydrophobicContact CG-CD1 3.85Å; A677-L732 HydrophobicContact CB-CB 3.91Å; A677-L732 HydrophobicContact CB-CD1 4.3Å; A678-L732 HydrophobicContact CB-CD1 4.06Å; A678-L732 HydrophobicContact CB-CD2 4.3Å; L681-L732 HydrophobicContact CD2-CD2 4.08Å; W719-L732 HydrophobicContact CH2-CD2 4.15Å; W719-L732 HydrophobicContact CZ3-CD2 4.04Å; L720-L732 HydrophobicContact CD1-CD2 3.79Å; A727-L732 HydrophobicContact CB-CD2 4.09Å; A727-L732 HydrophobicContact CB-CG 4.1Å; T728-L732 WeakPolarHBondContact O-CG 3.24Å; T728-L732 PolarHBondContact O-N 3.26Å; V730-L732 VanDerWaalsContact C-N 3.29Å; V730-L732 PolarHBondContact O-N 2.91Å; L732-L736 WeakPolarHBondContact O-CB 3.37Å; L732-L736 PolarHBondContact O-N 2.97Å; L732-L736 VanDerWaalsContact O-N 3.09Å
733K97Very high94.1Very high93 Ų9367 Ų6740%0.40436%0.357SS..Hα-helixtrans-70.4-32.4177.3-71.9174.4-177.8177.20112.2E673 A677 T729 V730 A737E673-K733 IonicContact OE2-NZ 2.68Å; E673-K733 PolarHBondContact OE2-NZ 2.77Å; A677-K733 HydrophobicContact CB-CD 4.5Å; A677-K733 HydrophobicContact CB-CG 3.95Å; T729-K733 HydrophobicContact CG2-CD 4.16Å; T729-K733 WeakPolarHBondContact O-CB 3.46Å; T729-K733 WeakPolarHBondContact O-CD 3.36Å; T729-K733 VanDerWaalsContact O-CG 3.24Å; T729-K733 WeakPolarHBondContact O-CG 3.47Å; T729-K733 PolarHBondContact O-N 3.44Å; V730-K733 CarbonylContact O-C 3.55Å; V730-K733 PolarHBondContact O-N 2.9Å; K733-A737 WeakPolarHBondContact O-CB 3.45Å; K733-A737 PolarHBondContact O-N 3.46Å
734E97.2Very high94.3Very high113 Ų11367.8 Ų67.853%0.52836%0.36SS..Hα-helixtrans-67.8-47.9173.1-73.4176.2149.400111.6V730 M731 L736 A737 E738V730-E734 HydrophobicContact CG1-CG 4.24Å; V730-E734 WeakPolarHBondContact O-CG 3.44Å; V730-E734 PolarHBondContact O-N 2.8Å; M731-E734 PolarHBondContact O-N 3.1Å; E734-L736 VanDerWaalsContact C-N 3.31Å; E734-L736 PolarHBondContact O-N 2.88Å; E734-A737 CarbonylContact O-C 3.52Å; E734-A737 WeakPolarHBondContact O-CA 3.34Å; E734-A737 WeakPolarHBondContact O-CB 3.4Å; E734-A737 PolarHBondContact O-N 2.89Å; E734-E738 WeakPolarHBondContact O-CG 3.34Å; E734-E738 PolarHBondContact O-N 2.99Å
735K96.6Very high94.9Very high63 Ų6369.6 Ų69.627%0.27438%0.379SS..Hα-helixtrans-55.9-44.4173.9-77.6-77.3161.4-142.70112.4L681 W719 M731 A737 E738 L739L681-K735 HydrophobicContact CD1-CB 4.2Å; L681-K735 HydrophobicContact CD2-CB 3.79Å; W719-K735 HydrophobicContact CE3-CD 4.28Å; W719-K735 HydrophobicContact CE3-CG 4.13Å; W719-K735 HydrophobicContact CH2-CG 4.01Å; W719-K735 HydrophobicContact CZ3-CB 4.42Å; W719-K735 HydrophobicContact CZ3-CD 4.44Å; W719-K735 HydrophobicContact CZ3-CG 3.78Å; M731-K735 WeakPolarHBondContact O-CB 3.45Å; M731-K735 WeakPolarHBondContact O-CG 3.32Å; M731-K735 PolarHBondContact O-N 3.36Å; K735-A737 VanDerWaalsContact C-N 3.31Å; K735-A737 PolarHBondContact O-N 2.93Å; K735-E738 IonicContact NZ-OE2 3.93Å; K735-E738 PolarHBondContact NZ-OE2 2.84Å; K735-E738 PolarHBondContact O-N 2.65Å; K735-L739 WeakPolarHBondContact O-CG 3.17Å; K735-L739 PolarHBondContact O-N 2.87Å; K735-L739 VanDerWaalsContact O-N 3.12Å
736L97.4Very high95.5Very high14 Ų1464.4 Ų64.47%0.07335%0.347CS..Hα-helixtrans-63.6-36174.8-179.754.3000112.2L681 F684 L732 E734 R740L681-L736 HydrophobicContact CB-CB 4.48Å; L681-L736 HydrophobicContact CD1-CB 4.16Å; F684-L736 HydrophobicContact CB-CD1 3.52Å; F684-L736 HydrophobicContact CD1-CD1 3.95Å; F684-L736 HydrophobicContact CD2-CD1 4.04Å; F684-L736 HydrophobicContact CG-CD1 3.54Å; L732-L736 WeakPolarHBondContact O-CB 3.37Å; L732-L736 PolarHBondContact O-N 2.97Å; L732-L736 VanDerWaalsContact O-N 3.09Å; E734-L736 VanDerWaalsContact C-N 3.31Å; E734-L736 PolarHBondContact O-N 2.88Å; L736-R740 HydrophobicContact CD1-CG 4.1Å; L736-R740 VanDerWaalsContact O-CB 3.27Å; L736-R740 WeakPolarHBondContact O-CB 3.29Å; L736-R740 WeakPolarHBondContact O-CG 3.47Å; L736-R740 PolarHBondContact O-N 3.11Å
737A97.8Very high96Very high56 Ų5663.2 Ų63.246%0.46332%0.322SS..Hα-helixtrans-70.2-37.3175.200000112.9K733 E734 K735 K741K733-A737 WeakPolarHBondContact O-CB 3.45Å; K733-A737 PolarHBondContact O-N 3.46Å; E734-A737 CarbonylContact O-C 3.52Å; E734-A737 WeakPolarHBondContact O-CA 3.34Å; E734-A737 WeakPolarHBondContact O-CB 3.4Å; E734-A737 PolarHBondContact O-N 2.89Å; K735-A737 VanDerWaalsContact C-N 3.31Å; K735-A737 PolarHBondContact O-N 2.93Å; A737-K741 VanDerWaalsContact O-CB 3.23Å; A737-K741 WeakPolarHBondContact O-CB 3.27Å; A737-K741 PolarHBondContact O-N 3.08Å
738E97Very high96.2Very high113 Ų11366.2 Ų66.253%0.52834%0.335SS..Hα-helixtrans-58.4-52.5172.8-69.5-177.2145.600111E734 K735 K741 L742E734-E738 WeakPolarHBondContact O-CG 3.34Å; E734-E738 PolarHBondContact O-N 2.99Å; K735-E738 IonicContact NZ-OE2 3.93Å; K735-E738 PolarHBondContact NZ-OE2 2.84Å; K735-E738 PolarHBondContact O-N 2.65Å; E738-K741 PolarHBondContact O-N 2.72Å; E738-L742 PolarHBondContact O-N 3.28Å
739L97.4Very high96.3Very high10 Ų1063.7 Ų63.75%0.05232%0.317CS..Hα-helixtrans-66.4-42.1-179-63.6173.4000112.4L681 F684 I685 K712 L713 A716 K735 K741 L742 C743L681-L739 HydrophobicContact CD1-CD1 3.65Å; F684-L739 HydrophobicContact CD1-CB 4.05Å; F684-L739 HydrophobicContact CD1-CD1 4.48Å; F684-L739 HydrophobicContact CE1-CB 3.72Å; I685-L739 HydrophobicContact CD1-CD1 4.35Å; I685-L739 HydrophobicContact CG1-CD1 3.88Å; K712-L739 HydrophobicContact CB-CD2 4.29Å; L713-L739 HydrophobicContact CD2-CD1 4.16Å; L713-L739 HydrophobicContact CD2-CD2 4.08Å; A716-L739 HydrophobicContact CB-CD1 3.8Å; A716-L739 HydrophobicContact CB-CD2 4.34Å; K735-L739 WeakPolarHBondContact O-CG 3.17Å; K735-L739 PolarHBondContact O-N 2.87Å; K735-L739 VanDerWaalsContact O-N 3.12Å; L739-K741 VanDerWaalsContact C-N 3.32Å; L739-K741 PolarHBondContact O-N 3.18Å; L739-L742 WeakPolarHBondContact O-CB 3.28Å; L739-L742 PolarHBondContact O-N 3.36Å; L739-C743 PolarHBondContact O-N 2.93Å; L739-C743 PolarHBondContact O-SG 3.35Å
740R97.1Very high96.3Very high135 Ų13562.3 Ų62.351%0.50931%0.309SS..Hα-helixtrans-60.6-40.1174.6-78.6173.9176.4-169.50.1112.3F684 L736 C743 Q744F684-R740 HydrophobicContact CD2-CG 4.03Å; F684-R740 HydrophobicContact CE1-CG 4.2Å; F684-R740 HydrophobicContact CE2-CG 3.48Å; F684-R740 VanDerWaalsContact CE2-CG 3.48Å; F684-R740 HydrophobicContact CZ-CB 4.34Å; F684-R740 HydrophobicContact CZ-CG 3.59Å; L736-R740 HydrophobicContact CD1-CG 4.1Å; L736-R740 VanDerWaalsContact O-CB 3.27Å; L736-R740 WeakPolarHBondContact O-CB 3.29Å; L736-R740 WeakPolarHBondContact O-CG 3.47Å; L736-R740 PolarHBondContact O-N 3.11Å; R740-C743 PolarHBondContact O-N 3.31Å; R740-Q744 WeakPolarHBondContact O-CB 3.37Å; R740-Q744 PolarHBondContact O-N 3.34Å
741K96.9Very high96.3Very high166 Ų16663 Ų6372%0.72231%0.306SS*.Hα-helixtrans-66.5-40.1176.9-178-176.8174.5-170.30111.9A737 E738 L739 Q744A737-K741 VanDerWaalsContact O-CB 3.23Å; A737-K741 WeakPolarHBondContact O-CB 3.27Å; A737-K741 PolarHBondContact O-N 3.08Å; E738-K741 PolarHBondContact O-N 2.72Å; L739-K741 VanDerWaalsContact C-N 3.32Å; L739-K741 PolarHBondContact O-N 3.18Å; K741-Q744 PolarHBondContact O-N 3.04Å
742L95.4Very high96.3Very high61 Ų6160.1 Ų60.132%0.31929%0.292SS..Hα-helixtrans-60.8-46174.4-176.268.5000111.3I709 K712 E738 L739 Q744I709-L742 HydrophobicContact CB-CD2 4.47Å; I709-L742 HydrophobicContact CG1-CD2 4.16Å; I709-L742 HydrophobicContact CG1-CG 4.14Å; I709-L742 HydrophobicContact CG2-CD2 4.45Å; K712-L742 HydrophobicContact CB-CD2 3.71Å; K712-L742 HydrophobicContact CG-CD2 3.75Å; E738-L742 PolarHBondContact O-N 3.28Å; L739-L742 WeakPolarHBondContact O-CB 3.28Å; L739-L742 PolarHBondContact O-N 3.36Å; L742-Q744 PolarHBondContact O-N 3.41Å
743C95.9Very high96.1Very high0 Ų062.9 Ų62.90%030%0.302CS..Hα-helixtrans-80.2-12.4-176.8-55.50000114.1F684 L739 R740 G745 L746 F747F684-C743 HydrophobicContact CZ-CB 4.32Å; L739-C743 PolarHBondContact O-N 2.93Å; L739-C743 PolarHBondContact O-SG 3.35Å; R740-C743 PolarHBondContact O-N 3.31Å; C743-G745 VanDerWaalsContact C-N 3.34Å; C743-G745 PolarHBondContact O-N 2.86Å; C743-L746 WeakPolarHBondContact O-CA 3.17Å; C743-L746 WeakPolarHBondContact O-CB 3.46Å; C743-L746 PolarHBondContact O-N 3.19Å; C743-F747 HydrophobicContact CB-CD1 4.28Å; C743-F747 HydrophobicContact CB-CD2 4.2Å; C743-F747 HydrophobicContact CB-CE1 3.9Å; C743-F747 HydrophobicContact CB-CE2 3.81Å; C743-F747 HydrophobicContact CB-CG 4.44Å; C743-F747 HydrophobicContact CB-CZ 3.66Å; C743-F747 PolarHBondContact O-N 3.03Å
744Q94.7Very high96Very high135 Ų13564.7 Ų64.763%0.63131%0.31SS*.Hα-helixtrans-54.8-44.3-171.6-172.2178.915.600113.4R740 K741 L742 L746 F748R740-Q744 WeakPolarHBondContact O-CB 3.37Å; R740-Q744 PolarHBondContact O-N 3.34Å; K741-Q744 PolarHBondContact O-N 3.04Å; L742-Q744 PolarHBondContact O-N 3.41Å; Q744-L746 VanDerWaalsContact C-N 3.32Å; Q744-L746 PolarHBondContact O-N 3.48Å; Q744-F748 VanDerWaalsContact O-CB 3.28Å; Q744-F748 WeakPolarHBondContact O-CB 3.5Å; Q744-F748 PolarHBondContact O-N 2.95Å
745G94.3Very high95.9Very high43 Ų4362.4 Ų62.444%0.44330%0.298SS..Hα-helixtrans-68.9-29.9178.800000113.4C743 R749C743-G745 VanDerWaalsContact C-N 3.34Å; C743-G745 PolarHBondContact O-N 2.86Å; G745-R749 WeakPolarHBondContact O-CG 3.19Å; G745-R749 PolarHBondContact O-N 2.81Å; G745-R749 PolarHBondContact O-NE 2.69Å
746L95Very high95.8Very high2 Ų260.8 Ų60.81%0.0129%0.291CS..Hα-helixtrans-70.4-54.9174.4176.360.1000110.9L692 Y697 V700 I709 C743 Q744 F748 R749 V750L692-L746 HydrophobicContact CD2-CD2 3.65Å; Y697-L746 HydrophobicContact CD1-CD1 4.4Å; Y697-L746 HydrophobicContact CD1-CD2 4.18Å; Y697-L746 HydrophobicContact CD1-CG 4.1Å; V700-L746 HydrophobicContact CG2-CD1 3.62Å; I709-L746 HydrophobicContact CD1-CD2 3.92Å; C743-L746 WeakPolarHBondContact O-CA 3.17Å; C743-L746 WeakPolarHBondContact O-CB 3.46Å; C743-L746 PolarHBondContact O-N 3.19Å; Q744-L746 VanDerWaalsContact C-N 3.32Å; Q744-L746 PolarHBondContact O-N 3.48Å; L746-F748 VanDerWaalsContact C-N 3.28Å; L746-F748 PolarHBondContact O-N 2.81Å; L746-R749 PolarHBondContact O-N 3.47Å; L746-R749 VanDerWaalsContact O-N 3.09Å; L746-V750 PolarHBondContact O-N 2.65Å
747F96Very high95.7Very high47 Ų4764.5 Ų64.521%0.20632%0.315CS..Hα-helixtrans-61.1-38.2-177.2-63.6-6.8000111.8F684 T688 Y697 C743 R749 V750 E751F684-F747 AromaticContact CE2-CE2 3.84Å; F684-F747 HydrophobicContact CE2-CE2 3.84Å; F684-F747 HydrophobicContact CE2-CZ 4.38Å; F684-F747 AromaticContact CZ-CE2 3.82Å; F684-F747 HydrophobicContact CZ-CE2 3.82Å; F684-F747 HydrophobicContact CZ-CZ 4.13Å; T688-F747 HydrophobicContact CG2-CE1 4.06Å; T688-F747 HydrophobicContact CG2-CZ 3.77Å; Y697-F747 HydrophobicContact CD1-CD1 4.45Å; Y697-F747 AromaticContact CE1-CD1 3.76Å; Y697-F747 HydrophobicContact CE1-CD1 3.76Å; Y697-F747 AromaticContact CE1-CE1 3.91Å; Y697-F747 HydrophobicContact CE1-CE1 3.91Å; C743-F747 HydrophobicContact CB-CD1 4.28Å; C743-F747 HydrophobicContact CB-CD2 4.2Å; C743-F747 HydrophobicContact CB-CE1 3.9Å; C743-F747 HydrophobicContact CB-CE2 3.81Å; C743-F747 HydrophobicContact CB-CG 4.44Å; C743-F747 HydrophobicContact CB-CZ 3.66Å; C743-F747 PolarHBondContact O-N 3.03Å; F747-R749 PolarHBondContact O-N 2.99Å; F747-V750 PolarHBondContact O-N 3.27Å; F747-E751 VanDerWaalsContact O-CB 3.28Å; F747-E751 WeakPolarHBondContact O-CB 3.48Å; F747-E751 PolarHBondContact O-N 2.92Å
748F96.3Very high95.6Very high65 Ų6568.8 Ų68.829%0.28533%0.326SS..Hα-helixtrans-60.6-40.3175179.8-102.9000113.5Q744 L746 E752 K821 P822 L825Q744-F748 VanDerWaalsContact O-CB 3.28Å; Q744-F748 WeakPolarHBondContact O-CB 3.5Å; Q744-F748 PolarHBondContact O-N 2.95Å; L746-F748 VanDerWaalsContact C-N 3.28Å; L746-F748 PolarHBondContact O-N 2.81Å; F748-E752 HydrophobicContact CD2-CG 4.42Å; F748-E752 HydrophobicContact CE1-CG 4.25Å; F748-E752 HydrophobicContact CE2-CG 3.97Å; F748-E752 HydrophobicContact CZ-CG 3.88Å; F748-E752 WeakPolarHBondContact O-CB 3.18Å; F748-E752 WeakPolarHBondContact O-CG 3.17Å; F748-E752 PolarHBondContact O-N 2.76Å; F748-E752 VanDerWaalsContact O-N 3.13Å; F748-K821 HydrophobicContact CD1-CG 4.37Å; F748-K821 HydrophobicContact CE1-CD 4.4Å; F748-K821 HydrophobicContact CE1-CG 3.87Å; F748-P822 HydrophobicContact CD1-CG 4.49Å; F748-P822 HydrophobicContact CE1-CG 3.86Å; F748-L825 HydrophobicContact CE1-CD2 4.36Å; F748-L825 HydrophobicContact CZ-CD2 3.82Å
749R95.9Very high95.4Very high19 Ų1965.6 Ų65.67%0.07231%0.309CS..Hα-helixtrans-66.7-39.4177.7-71.9172.6-62.7-178.415.4111.7V700 Q705 G745 L746 F747 R753 T819 E820V700-R749 HydrophobicContact CB-CB 3.83Å; V700-R749 HydrophobicContact CG1-CB 4.02Å; V700-R749 HydrophobicContact CG2-CB 4.08Å; V700-R749 PolarHBondContact O-NE 2.69Å; V700-R749 PolarHBondContact O-NH1 2.7Å; V700-R749 VanDerWaalsContact O-NH1 3.11Å; V700-R749 PolarHBondContact O-NH2 3.26Å; V700-R749 VanDerWaalsContact O-NH2 3.12Å; Q705-R749 VanDerWaalsContact OE1-NH1 3.08Å; G745-R749 WeakPolarHBondContact O-CG 3.19Å; G745-R749 PolarHBondContact O-N 2.81Å; G745-R749 PolarHBondContact O-NE 2.69Å; L746-R749 PolarHBondContact O-N 3.47Å; L746-R749 VanDerWaalsContact O-N 3.09Å; F747-R749 PolarHBondContact O-N 2.99Å; R749-R753 WeakPolarHBondContact O-CG 3.49Å; R749-R753 PolarHBondContact O-N 2.68Å; R749-T819 WeakPolarHBondContact CD-O 3.38Å; R749-T819 PolarHBondContact NH1-O 2.78Å; R749-E820 WeakPolarHBondContact CD-O 3.4Å
750V95.8Very high95.4Very high6 Ų666.6 Ų66.64%0.03631%0.314CS..Hα-helixtrans-67.6-50.7175.3-179.70000111.1E696 Y697 V700 L746 F747 E752 R753 K754E696-V750 HydrophobicContact CB-CG1 4.08Å; Y697-V750 HydrophobicContact CD1-CG2 3.7Å; Y697-V750 HydrophobicContact CD2-CG1 4.45Å; Y697-V750 HydrophobicContact CD2-CG2 4.26Å; Y697-V750 HydrophobicContact CE1-CB 4.45Å; Y697-V750 HydrophobicContact CE1-CG2 3.89Å; Y697-V750 HydrophobicContact CE2-CG1 4.07Å; Y697-V750 HydrophobicContact CE2-CG2 4.45Å; Y697-V750 HydrophobicContact CG-CG2 3.88Å; V700-V750 HydrophobicContact CG2-CG2 3.51Å; L746-V750 PolarHBondContact O-N 2.65Å; F747-V750 PolarHBondContact O-N 3.27Å; V750-E752 VanDerWaalsContact C-N 3.32Å; V750-E752 PolarHBondContact O-N 3.03Å; V750-R753 PolarHBondContact O-N 3.22Å; V750-K754 WeakPolarHBondContact O-CB 3.32Å; V750-K754 PolarHBondContact O-N 3.32Å
751E95.1Very high95.3Very high103 Ų10363.1 Ų63.148%0.48131%0.311SS..Hα-helixtrans-62.5-37-174.6-172.6-176.2177.400112.5F747 K755F747-E751 VanDerWaalsContact O-CB 3.28Å; F747-E751 WeakPolarHBondContact O-CB 3.48Å; F747-E751 PolarHBondContact O-N 2.92Å; E751-K755 HydrophobicContact CG-CD 4.34Å; E751-K755 WeakPolarHBondContact O-CD 3.32Å; E751-K755 VanDerWaalsContact O-CG 3.25Å; E751-K755 WeakPolarHBondContact O-CG 3.27Å; E751-K755 PolarHBondContact O-N 2.76Å; E751-K755 WeakPolarHBondContact OE1-CE 3.39Å; E751-K755 IonicContact OE1-NZ 3.66Å; E751-K755 PolarHBondContact OE1-NZ 2.88Å
752E95.6Very high95.3Very high18 Ų1857 Ų578%0.08429%0.291CS..Hα-helixtrans-63.3-53.9171.3-80.3-68.9161.800111.5F748 V750 K754 K755 W756 P822 S826F748-E752 HydrophobicContact CD2-CG 4.42Å; F748-E752 HydrophobicContact CE1-CG 4.25Å; F748-E752 HydrophobicContact CE2-CG 3.97Å; F748-E752 HydrophobicContact CZ-CG 3.88Å; F748-E752 WeakPolarHBondContact O-CB 3.18Å; F748-E752 WeakPolarHBondContact O-CG 3.17Å; F748-E752 PolarHBondContact O-N 2.76Å; F748-E752 VanDerWaalsContact O-N 3.13Å; V750-E752 VanDerWaalsContact C-N 3.32Å; V750-E752 PolarHBondContact O-N 3.03Å; E752-K754 VanDerWaalsContact C-N 3.32Å; E752-K754 PolarHBondContact O-N 3.34Å; E752-K755 PolarHBondContact O-N 2.82Å; E752-W756 HydrophobicContact CB-CZ2 4.27Å; E752-W756 PolarHBondContact O-N 3.22Å; E752-W756 VanDerWaalsContact O-N 3.13Å; E752-W756 PolarHBondContact O-NE1 2.98Å; E752-W756 PolarHBondContact OE2-NE1 3.07Å; E752-W756 VanDerWaalsContact OE2-NE1 3.16Å; E752-P822 HydrophobicContact CB-CG 4.05Å; E752-P822 HydrophobicContact CG-CG 4.01Å; E752-S826 PolarHBondContact OE1-N 2.7Å; E752-S826 WeakPolarHBondContact OE2-CB 3.32Å; E752-S826 PolarHBondContact OE2-N 3.33Å; E752-S826 PolarHBondContact OE2-OG 3.15Å
753R93.8Very high95.4Very high58 Ų5854.1 Ų54.122%0.21928%0.276CS..Hα-helixtrans-57.5-42.5-179.9-76.1177.6-175.4-90.3-24112.9E699 V700 R749 V750 K755 W756 P757E699-R753 WeakPolarHBondContact OE1-CD 3.48Å; E699-R753 IonicContact OE1-CZ 2.95Å; E699-R753 IonicContact OE1-NE 2.91Å; E699-R753 IonicContact OE1-NH1 2.69Å; E699-R753 PolarHBondContact OE1-NH1 3.45Å; V700-R753 VanDerWaalsContact CG1-CD 3.43Å; R749-R753 WeakPolarHBondContact O-CG 3.49Å; R749-R753 PolarHBondContact O-N 2.68Å; V750-R753 PolarHBondContact O-N 3.22Å; R753-K755 PolarHBondContact O-N 2.98Å; R753-W756 HydrophobicContact CB-CE3 4.48Å; R753-W756 HydrophobicContact CG-CE3 3.95Å; R753-W756 HydrophobicContact CG-CH2 3.92Å; R753-W756 HydrophobicContact CG-CZ2 4.46Å; R753-W756 HydrophobicContact CG-CZ3 3.64Å; R753-W756 PolarHBondContact O-N 3.08Å; R753-P757 WeakPolarHBondContact O-CD 3.43Å
754K94.2Very high95.4Very high132 Ų13256 Ų5657%0.57429%0.286SS*.Hα-helixtrans-62.5-29.2178.8-156.1-178.4-166.296.10112.7E696 V750 E752E696-K754 IonicContact OE1-NZ 3.82Å; E696-K754 PolarHBondContact OE1-NZ 2.78Å; E696-K754 IonicContact OE2-NZ 3.24Å; E696-K754 PolarHBondContact OE2-NZ 2.88Å; V750-K754 WeakPolarHBondContact O-CB 3.32Å; V750-K754 PolarHBondContact O-N 3.32Å; E752-K754 VanDerWaalsContact C-N 3.32Å; E752-K754 PolarHBondContact O-N 3.34Å
755K95.1Very high95.5Very high64 Ų6454.3 Ų54.328%0.27828%0.281SS..Hα-helixtrans-88.4-20.7179.4-71.8172.8-172.9175.50114.1E751 E752 R753 R759E751-K755 HydrophobicContact CG-CD 4.34Å; E751-K755 WeakPolarHBondContact O-CD 3.32Å; E751-K755 VanDerWaalsContact O-CG 3.25Å; E751-K755 WeakPolarHBondContact O-CG 3.27Å; E751-K755 PolarHBondContact O-N 2.76Å; E751-K755 WeakPolarHBondContact OE1-CE 3.39Å; E751-K755 IonicContact OE1-NZ 3.66Å; E751-K755 PolarHBondContact OE1-NZ 2.88Å; E752-K755 PolarHBondContact O-N 2.82Å; R753-K755 PolarHBondContact O-N 2.98Å; K755-R759 WeakPolarHBondContact O-CB 3.21Å; K755-R759 VanDerWaalsContact O-CG 3.27Å; K755-R759 WeakPolarHBondContact O-CG 3.41Å; K755-R759 PolarHBondContact O-N 3.07Å; K755-R759 VanDerWaalsContact O-N 3.17Å
756W94.8Very high95.6Very high30 Ų3053.7 Ų53.711%0.11427%0.267CS..Hα-helixtrans-60.3-44.4-174.8-67.9-13.4000114.9E752 R753 E758 R759 L760 Q813 P822 L824E752-W756 HydrophobicContact CB-CZ2 4.27Å; E752-W756 PolarHBondContact O-N 3.22Å; E752-W756 VanDerWaalsContact O-N 3.13Å; E752-W756 PolarHBondContact O-NE1 2.98Å; E752-W756 PolarHBondContact OE2-NE1 3.07Å; E752-W756 VanDerWaalsContact OE2-NE1 3.16Å; R753-W756 HydrophobicContact CB-CE3 4.48Å; R753-W756 HydrophobicContact CG-CE3 3.95Å; R753-W756 HydrophobicContact CG-CH2 3.92Å; R753-W756 HydrophobicContact CG-CZ2 4.46Å; R753-W756 HydrophobicContact CG-CZ3 3.64Å; R753-W756 PolarHBondContact O-N 3.08Å; W756-E758 PolarHBondContact O-N 3.21Å; W756-R759 PolarHBondContact O-N 3.14Å; W756-L760 HydrophobicContact CB-CD1 4.2Å; W756-L760 VanDerWaalsContact O-CB 3.23Å; W756-L760 WeakPolarHBondContact O-CB 3.27Å; W756-L760 WeakPolarHBondContact O-CG 3.26Å; W756-L760 PolarHBondContact O-N 3.04Å; W756-Q813 HydrophobicContact CH2-CG 3.76Å; W756-Q813 HydrophobicContact CZ2-CG 4.35Å; W756-Q813 HydrophobicContact CZ3-CG 4.19Å; W756-P822 HydrophobicContact CH2-CB 4.02Å; W756-P822 HydrophobicContact CZ2-CB 3.55Å; W756-P822 HydrophobicContact CZ2-CG 4.32Å; W756-L824 HydrophobicContact CD2-CD2 3.9Å; W756-L824 HydrophobicContact CE3-CD2 4.44Å; W756-L824 HydrophobicContact CG-CD2 4.01Å; W756-L824 HydrophobicContact CZ2-CB 4.15Å; W756-L824 HydrophobicContact CZ2-CD2 4.49Å; W756-L824 WeakPolarHBondContact CZ2-O 3.34Å; W756-L824 PolarHBondContact NE1-O 2.78Å
757P95Very high95.6Very high92 Ų9253.6 Ų53.660%0.59727%0.267SS*.Hα-helixtrans-60.5-49.4-175.4-24.934.9000112.9R753 S761R753-P757 WeakPolarHBondContact O-CD 3.43Å; P757-S761 VanDerWaalsContact O-CB 3.28Å; P757-S761 WeakPolarHBondContact O-CB 3.47Å; P757-S761 PolarHBondContact O-N 3.02Å
758E95.4Very high95.6Very high145 Ų14555.3 Ų55.368%0.67828%0.278SS*.Hα-helixtrans-61.2-50.3177.1-174.5-167.5-179.400111.1W756 L760 S761 A762W756-E758 PolarHBondContact O-N 3.21Å; E758-L760 PolarHBondContact O-N 2.67Å; E758-S761 PolarHBondContact O-N 3.17Å; E758-A762 WeakPolarHBondContact O-CB 3.29Å; E758-A762 PolarHBondContact O-N 3.39Å
759R94.6Very high95.5Very high47 Ų4757.4 Ų57.418%0.17729%0.289CS..Hα-helixtrans-69.5-35.9-174.7-68.6-179.4178.3-132.9-16.7113.2K755 W756 L763 S826 I829 E830K755-R759 WeakPolarHBondContact O-CB 3.21Å; K755-R759 VanDerWaalsContact O-CG 3.27Å; K755-R759 WeakPolarHBondContact O-CG 3.41Å; K755-R759 PolarHBondContact O-N 3.07Å; K755-R759 VanDerWaalsContact O-N 3.17Å; W756-R759 PolarHBondContact O-N 3.14Å; R759-L763 WeakPolarHBondContact O-CB 3.43Å; R759-L763 PolarHBondContact O-N 2.66Å; R759-S826 VanDerWaalsContact NH1-C 3.25Å; R759-S826 PolarHBondContact NH1-O 2.86Å; R759-I829 HydrophobicContact CB-CD1 4.1Å; R759-I829 HydrophobicContact CB-CG2 3.97Å; R759-E830 IonicContact CZ-OE1 3.63Å; R759-E830 IonicContact CZ-OE2 3.99Å; R759-E830 IonicContact NH1-OE1 3.59Å; R759-E830 PolarHBondContact NH1-OE1 3.45Å; R759-E830 IonicContact NH1-OE2 3.78Å; R759-E830 PolarHBondContact NH1-OE2 2.88Å; R759-E830 IonicContact NH2-OE1 2.76Å; R759-E830 PolarHBondContact NH2-OE1 2.77Å; R759-E830 IonicContact NH2-OE2 2.84Å
760L95.9Very high95.5Very high30 Ų3056.5 Ų56.516%0.15729%0.285CS..Hα-helixtrans-69.6-43.5174.3-70171000111W756 E758 L763 D764 L810 L824 I829W756-L760 HydrophobicContact CB-CD1 4.2Å; W756-L760 VanDerWaalsContact O-CB 3.23Å; W756-L760 WeakPolarHBondContact O-CB 3.27Å; W756-L760 WeakPolarHBondContact O-CG 3.26Å; W756-L760 PolarHBondContact O-N 3.04Å; E758-L760 PolarHBondContact O-N 2.67Å; L760-L763 PolarHBondContact O-N 2.86Å; L760-D764 WeakPolarHBondContact O-CB 3.47Å; L760-D764 PolarHBondContact O-N 2.8Å; L760-L810 HydrophobicContact CD1-CD2 4.09Å; L760-L810 HydrophobicContact CD2-CD2 4.44Å; L760-L824 HydrophobicContact CD1-CD2 4.16Å; L760-L824 HydrophobicContact CD2-CD2 4.32Å; L760-I829 HydrophobicContact CD2-CD1 3.97Å; L760-I829 HydrophobicContact CG-CD1 4.25Å
761S96.6Very high95.5Very high63 Ų6358.1 Ų58.144%0.44130%0.297SS..Hα-helixtrans-61.3-44175.1-175.40000112P757 E758 L763 D764 N765P757-S761 VanDerWaalsContact O-CB 3.28Å; P757-S761 WeakPolarHBondContact O-CB 3.47Å; P757-S761 PolarHBondContact O-N 3.02Å; E758-S761 PolarHBondContact O-N 3.17Å; S761-L763 PolarHBondContact O-N 3.31Å; S761-D764 PolarHBondContact O-N 3.08Å; S761-N765 WeakPolarHBondContact O-CB 3.46Å; S761-N765 VanDerWaalsContact O-CG 3.31Å; S761-N765 PolarHBondContact O-N 2.87Å; S761-N765 PolarHBondContact O-ND2 3.22Å
762A96.2Very high95.4Very high37 Ų3759.6 Ų59.631%0.30631%0.305SS..Hα-helixtrans-63.5-39.7175.500000112.6E758 L766 M833E758-A762 WeakPolarHBondContact O-CB 3.29Å; E758-A762 PolarHBondContact O-N 3.39Å; A762-L766 WeakPolarHBondContact O-CB 3.16Å; A762-L766 PolarHBondContact O-N 2.9Å; A762-M833 HydrophobicContact CB-CE 3.57Å; A762-M833 HydrophobicContact CB-SD 4.39Å
763L96.8Very high95.3Very high0 Ų060.4 Ų60.40%031%0.309CS..Hα-helixtrans-65.7-42173.2175.862.2000112.1R759 L760 S761 L766 L767 T802 W805 K806 I829 M833R759-L763 WeakPolarHBondContact O-CB 3.43Å; R759-L763 PolarHBondContact O-N 2.66Å; L760-L763 PolarHBondContact O-N 2.86Å; S761-L763 PolarHBondContact O-N 3.31Å; L763-L766 PolarHBondContact O-N 2.88Å; L763-L767 HydrophobicContact CD1-CD1 4.07Å; L763-L767 HydrophobicContact CD1-CG 4.17Å; L763-L767 HydrophobicContact CG-CD1 3.9Å; L763-L767 HydrophobicContact CG-CG 4.45Å; L763-L767 WeakPolarHBondContact O-CB 3.5Å; L763-L767 VanDerWaalsContact O-CG 3.31Å; L763-L767 WeakPolarHBondContact O-CG 3.32Å; L763-L767 PolarHBondContact O-N 3.01Å; L763-T802 HydrophobicContact CD1-CG2 3.81Å; L763-W805 HydrophobicContact CD2-CZ3 4.06Å; L763-K806 HydrophobicContact CD2-CB 4.34Å; L763-K806 HydrophobicContact CD2-CD 4.26Å; L763-K806 HydrophobicContact CD2-CG 3.95Å; L763-I829 HydrophobicContact CB-CG2 4.11Å; L763-I829 HydrophobicContact CD2-CG2 4.12Å; L763-M833 HydrophobicContact CB-CG 4.02Å; L763-M833 HydrophobicContact CB-SD 4.27Å; L763-M833 HydrophobicContact CD1-CG 3.77Å; L763-M833 HydrophobicContact CG-CG 4.46Å
764D96.8Very high95.3Very high39 Ų3958.3 Ų58.321%0.20930%0.302CS..Hα-helixtrans-64.5-44.5177-82.8-44.2000112L760 S761 L766 L767 N768 W803 K806L760-D764 WeakPolarHBondContact O-CB 3.47Å; L760-D764 PolarHBondContact O-N 2.8Å; S761-D764 PolarHBondContact O-N 3.08Å; D764-L766 VanDerWaalsContact C-N 3.32Å; D764-L766 PolarHBondContact O-N 3.36Å; D764-L767 PolarHBondContact O-N 3.24Å; D764-N768 VanDerWaalsContact O-CB 3.31Å; D764-N768 WeakPolarHBondContact O-CB 3.2Å; D764-N768 PolarHBondContact O-N 2.78Å; D764-N768 PolarHBondContact O-ND2 2.93Å; D764-N768 VanDerWaalsContact O-ND2 3.13Å; D764-W803 WeakPolarHBondContact OD1-CH2 3.5Å; D764-K806 IonicContact OD1-NZ 3.77Å; D764-K806 PolarHBondContact OD1-NZ 3.41Å; D764-K806 IonicContact OD2-NZ 3.68Å; D764-K806 PolarHBondContact OD2-NZ 3.45Å
765N96.3Very high95.2Very high100 Ų10058.5 Ų58.554%0.53530%0.303SS..Hα-helixtrans-60.7-42.1175.3-73.5-30.7000111.5S761 H769S761-N765 WeakPolarHBondContact O-CB 3.46Å; S761-N765 VanDerWaalsContact O-CG 3.31Å; S761-N765 PolarHBondContact O-N 2.87Å; S761-N765 PolarHBondContact O-ND2 3.22Å; N765-H769 VanDerWaalsContact O-CB 3.31Å; N765-H769 WeakPolarHBondContact O-CB 3.25Å; N765-H769 PolarHBondContact O-N 3.42Å
766L95.8Very high95Very high30 Ų3057.2 Ų57.216%0.15731%0.308CS..Hα-helixtrans-66.2-42.3174.9-17564.8000112.2A762 L763 D764 H769 S770 M833 L836 D837A762-L766 WeakPolarHBondContact O-CB 3.16Å; A762-L766 PolarHBondContact O-N 2.9Å; L763-L766 PolarHBondContact O-N 2.88Å; D764-L766 VanDerWaalsContact C-N 3.32Å; D764-L766 PolarHBondContact O-N 3.36Å; L766-H769 PolarHBondContact O-N 2.79Å; L766-S770 VanDerWaalsContact O-CB 3.25Å; L766-S770 WeakPolarHBondContact O-CB 3.49Å; L766-S770 PolarHBondContact O-N 2.68Å; L766-S770 PolarHBondContact O-OG 2.85Å; L766-M833 HydrophobicContact CD2-CB 4.02Å; L766-M833 HydrophobicContact CD2-CG 4.33Å; L766-M833 WeakPolarHBondContact CD2-O 3.31Å; L766-L836 HydrophobicContact CD2-CB 4.16Å; L766-L836 HydrophobicContact CD2-CD2 4.09Å; L766-L836 HydrophobicContact CD2-CG 4.2Å; L766-L836 HydrophobicContact CG-CD2 3.88Å; L766-L836 HydrophobicContact CG-CG 4.16Å; L766-D837 HydrophobicContact CD1-CB 4.26Å; L766-D837 HydrophobicContact CD2-CB 4.17Å
767L96.7Very high94.7Very high0 Ų056 Ų560%030%0.304CS..Hα-helixtrans-62-44.7176-80.2166.1000112.1L763 D764 S770 S771 I799 T802 W803 K806 L836L763-L767 HydrophobicContact CD1-CD1 4.07Å; L763-L767 HydrophobicContact CD1-CG 4.17Å; L763-L767 HydrophobicContact CG-CD1 3.9Å; L763-L767 HydrophobicContact CG-CG 4.45Å; L763-L767 WeakPolarHBondContact O-CB 3.5Å; L763-L767 VanDerWaalsContact O-CG 3.31Å; L763-L767 WeakPolarHBondContact O-CG 3.32Å; L763-L767 PolarHBondContact O-N 3.01Å; D764-L767 PolarHBondContact O-N 3.24Å; L767-S770 PolarHBondContact O-N 2.8Å; L767-S771 WeakPolarHBondContact O-CB 3.47Å; L767-S771 PolarHBondContact O-N 3Å; L767-S771 PolarHBondContact O-OG 3.03Å; L767-I799 HydrophobicContact CD2-CG2 4.34Å; L767-T802 HydrophobicContact CD1-CG2 4.34Å; L767-T802 HydrophobicContact CD2-CG2 3.89Å; L767-T802 HydrophobicContact CG-CG2 4.4Å; L767-W803 HydrophobicContact CB-CZ2 4.26Å; L767-W803 HydrophobicContact CD1-CD2 3.99Å; L767-W803 HydrophobicContact CD1-CE3 4.38Å; L767-W803 HydrophobicContact CD1-CG 4.33Å; L767-W803 HydrophobicContact CD1-CZ2 4.24Å; L767-W803 HydrophobicContact CD2-CG 4.25Å; L767-K806 HydrophobicContact CD1-CD 4.44Å; L767-L836 HydrophobicContact CD2-CD2 3.65Å; L767-L836 HydrophobicContact CG-CD2 3.99Å
768N95.2Very high94.4Very high83 Ų8356.2 Ų56.244%0.44429%0.293SS..Hα-helixtrans-64.4-46.8177.4-71.8-30.2000111.1D764 S771 M772D764-N768 VanDerWaalsContact O-CB 3.31Å; D764-N768 WeakPolarHBondContact O-CB 3.2Å; D764-N768 PolarHBondContact O-N 2.78Å; D764-N768 PolarHBondContact O-ND2 2.93Å; D764-N768 VanDerWaalsContact O-ND2 3.13Å; N768-S771 PolarHBondContact O-N 2.86Å; N768-M772 WeakPolarHBondContact O-CB 3.36Å; N768-M772 WeakPolarHBondContact O-CG 3.22Å; N768-M772 PolarHBondContact O-N 2.86Å
769H95Very high94.1Very high109 Ų10955.7 Ų55.751%0.50529%0.294SS..Hα-helixtrans-61.6-45175.9-169.994.8000111.9N765 L766 S771 M772 F773N765-H769 VanDerWaalsContact O-CB 3.31Å; N765-H769 WeakPolarHBondContact O-CB 3.25Å; N765-H769 PolarHBondContact O-N 3.42Å; L766-H769 PolarHBondContact O-N 2.79Å; H769-S771 VanDerWaalsContact C-N 3.33Å; H769-S771 PolarHBondContact O-N 3.46Å; H769-M772 PolarHBondContact O-N 3.11Å; H769-F773 WeakPolarHBondContact O-CB 3.41Å; H769-F773 PolarHBondContact O-N 3.22Å
770S95.3Very high93.6Very high0 Ų055.8 Ų55.80%030%0.298CS..Hα-helixtrans-61.2-41.2178-56.40000112.1L766 L767 F773 L774 L836 V840L766-S770 VanDerWaalsContact O-CB 3.25Å; L766-S770 WeakPolarHBondContact O-CB 3.49Å; L766-S770 PolarHBondContact O-N 2.68Å; L766-S770 PolarHBondContact O-OG 2.85Å; L767-S770 PolarHBondContact O-N 2.8Å; S770-F773 PolarHBondContact O-N 3.22Å; S770-L774 WeakPolarHBondContact O-CB 3.33Å; S770-L774 PolarHBondContact O-N 3.28Å; S770-L836 WeakPolarHBondContact OG-CG 3.29Å; S770-V840 WeakPolarHBondContact OG-CG2 3.07Å
771S94.9Very high93Very high41 Ų4158.4 Ų58.429%0.28732%0.316SS..Hα-helixtrans-68.5-40.5178.2-56.10000111.9L767 N768 H769 K775L767-S771 WeakPolarHBondContact O-CB 3.47Å; L767-S771 PolarHBondContact O-N 3Å; L767-S771 PolarHBondContact O-OG 3.03Å; N768-S771 PolarHBondContact O-N 2.86Å; H769-S771 VanDerWaalsContact C-N 3.33Å; H769-S771 PolarHBondContact O-N 3.46Å; S771-K775 WeakPolarHBondContact O-CB 3.45Å; S771-K775 PolarHBondContact O-N 3.44Å
772M93.5Very high92Very high133 Ų13364.1 Ų64.166%0.65534%0.336SS*.Hα-helixtrans-67.4-40.1174.5-73.3-69.9-79.900112N768 H769 K775 G776N768-M772 WeakPolarHBondContact O-CB 3.36Å; N768-M772 WeakPolarHBondContact O-CG 3.22Å; N768-M772 PolarHBondContact O-N 2.86Å; H769-M772 PolarHBondContact O-N 3.11Å; M772-K775 PolarHBondContact O-N 3.16Å; M772-G776 PolarHBondContact O-N 2.7Å
773F93.9Very high90.9Very high36 Ų3668.8 Ų68.816%0.15835%0.353CS..Hα-helixtrans-61.9-48.6173.7176.2-95.8000111.7H769 S770 K775 G776 A777 F787 L795 L843 L844H769-F773 WeakPolarHBondContact O-CB 3.41Å; H769-F773 PolarHBondContact O-N 3.22Å; S770-F773 PolarHBondContact O-N 3.22Å; F773-K775 VanDerWaalsContact C-N 3.33Å; F773-K775 PolarHBondContact O-N 3.42Å; F773-G776 PolarHBondContact O-N 3.28Å; F773-G776 VanDerWaalsContact O-N 3.17Å; F773-A777 WeakPolarHBondContact O-CB 3.23Å; F773-A777 PolarHBondContact O-N 2.75Å; F773-F787 HydrophobicContact CE2-CZ 4.36Å; F773-F787 HydrophobicContact CZ-CE1 4.16Å; F773-F787 HydrophobicContact CZ-CE2 4.31Å; F773-F787 AromaticContact CZ-CZ 3.72Å; F773-F787 HydrophobicContact CZ-CZ 3.72Å; F773-L795 HydrophobicContact CD1-CD2 3.8Å; F773-L795 HydrophobicContact CE1-CD2 4.19Å; F773-L843 HydrophobicContact CE1-CB 3.68Å; F773-L843 HydrophobicContact CE1-CD1 4.02Å; F773-L843 HydrophobicContact CZ-CB 3.79Å; F773-L844 HydrophobicContact CD2-CD2 3.94Å; F773-L844 HydrophobicContact CE2-CD2 3.54Å; F773-L844 HydrophobicContact CE2-CG 4.09Å; F773-L844 HydrophobicContact CZ-CD2 4.3Å; F773-L844 HydrophobicContact CZ-CG 4.43Å
774L93.5Very high89.9Confident13 Ų1371.4 Ų71.47%0.06837%0.367CS..Hα-helixtrans-59.5-42175.917564.5000112.2S770 A777 R778 M792 L795 E796 I799S770-L774 WeakPolarHBondContact O-CB 3.33Å; S770-L774 PolarHBondContact O-N 3.28Å; L774-A777 PolarHBondContact O-N 2.81Å; L774-R778 PolarHBondContact O-N 2.83Å; L774-M792 HydrophobicContact CD1-CB 3.89Å; L774-M792 HydrophobicContact CD1-CG 4.35Å; L774-M792 WeakPolarHBondContact CD1-O 3.37Å; L774-L795 HydrophobicContact CB-CD2 4.09Å; L774-E796 HydrophobicContact CD2-CB 3.62Å; L774-E796 HydrophobicContact CD2-CG 4.09Å; L774-I799 HydrophobicContact CB-CD1 4.32Å; L774-I799 HydrophobicContact CD2-CD1 3.99Å
775K92.6Very high89.3Confident136 Ų13671.7 Ų71.759%0.59137%0.367SS*.Hα-helixtrans-63-42.3175.1-174.1179179.7-1780111.5S771 M772 F773 L779S771-K775 WeakPolarHBondContact O-CB 3.45Å; S771-K775 PolarHBondContact O-N 3.44Å; M772-K775 PolarHBondContact O-N 3.16Å; F773-K775 VanDerWaalsContact C-N 3.33Å; F773-K775 PolarHBondContact O-N 3.42Å; K775-L779 HydrophobicContact CG-CD1 4.29Å; K775-L779 WeakPolarHBondContact O-CD1 3.47Å; K775-L779 VanDerWaalsContact O-CG 3.29Å; K775-L779 WeakPolarHBondContact O-CG 3.46Å; K775-L779 PolarHBondContact O-N 2.83Å
776G90.6Very high88.7Confident38 Ų3869.3 Ų69.339%0.39235%0.354SS..Hα-helixtrans-62.5-46.5173.900000112.6M772 F773 R778 L779 I780M772-G776 PolarHBondContact O-N 2.7Å; F773-G776 PolarHBondContact O-N 3.28Å; F773-G776 VanDerWaalsContact O-N 3.17Å; G776-R778 VanDerWaalsContact C-N 3.33Å; G776-R778 PolarHBondContact O-N 3Å; G776-L779 PolarHBondContact O-N 3.34Å; G776-I780 PolarHBondContact O-N 3.48Å
777A88.3Confident88.5Confident3 Ų368.5 Ų68.53%0.02535%0.349CS..Hα-helixtrans-56.2-43.6177.100000112.7F773 L774 L779 I780 Q785 F787 M792F773-A777 WeakPolarHBondContact O-CB 3.23Å; F773-A777 PolarHBondContact O-N 2.75Å; L774-A777 PolarHBondContact O-N 2.81Å; A777-L779 VanDerWaalsContact C-N 3.29Å; A777-L779 PolarHBondContact O-N 3.17Å; A777-I780 WeakPolarHBondContact O-CG1 3.36Å; A777-I780 PolarHBondContact O-N 2.85Å; A777-Q785 PolarHBondContact O-NE2 2.96Å; A777-F787 HydrophobicContact CB-CD2 3.47Å; A777-F787 VanDerWaalsContact CB-CD2 3.47Å; A777-F787 HydrophobicContact CB-CE2 3.62Å; A777-F787 HydrophobicContact CB-CG 4.42Å; A777-M792 HydrophobicContact CB-SD 3.98Å
778R89Confident88.2Confident98 Ų9871.7 Ų71.737%0.3737%0.369SS..Hα-helixtrans-71.3-16.8176.1-77.6-178.3162.2157.5-1.9114.8L774 G776 E789 M792 E796L774-R778 PolarHBondContact O-N 2.83Å; G776-R778 VanDerWaalsContact C-N 3.33Å; G776-R778 PolarHBondContact O-N 3Å; R778-E789 IonicContact NE-OE1 2.62Å; R778-E789 IonicContact NH2-OE1 3.17Å; R778-E789 PolarHBondContact NH2-OE1 2.82Å; R778-M792 HydrophobicContact CG-CE 4.45Å; R778-M792 HydrophobicContact CG-SD 3.72Å; R778-E796 IonicContact CZ-OE1 3.91Å; R778-E796 IonicContact CZ-OE2 2.66Å; R778-E796 IonicContact NH1-OE1 2.68Å; R778-E796 PolarHBondContact NH1-OE1 2.83Å; R778-E796 IonicContact NH1-OE2 3.39Å; R778-E796 PolarHBondContact NH1-OE2 2.86Å; R778-E796 IonicContact NH2-OE1 3.88Å; R778-E796 IonicContact NH2-OE2 3.67Å; R778-E796 PolarHBondContact NH2-OE2 2.92Å
779L88.6Confident87.8Confident134 Ų13472.9 Ų72.970%0.70237%0.372SS*.THydrogen-bonded Turntrans-91.1-3.1176.2-70.7168.8000113.3K775 G776 A777 P781K775-L779 HydrophobicContact CG-CD1 4.29Å; K775-L779 WeakPolarHBondContact O-CD1 3.47Å; K775-L779 VanDerWaalsContact O-CG 3.29Å; K775-L779 WeakPolarHBondContact O-CG 3.46Å; K775-L779 PolarHBondContact O-N 2.83Å; G776-L779 PolarHBondContact O-N 3.34Å; A777-L779 VanDerWaalsContact C-N 3.29Å; A777-L779 PolarHBondContact O-N 3.17Å; L779-P781 WeakPolarHBondContact O-CD 3.36Å
780I85.3Confident87.5Confident49 Ų4972.8 Ų72.825%0.25138%0.379SS..SBendtrans-70.1125.4172.7-55.3174.7000108.9G776 A777 D784 Q785 F787G776-I780 PolarHBondContact O-N 3.48Å; A777-I780 WeakPolarHBondContact O-CG1 3.36Å; A777-I780 PolarHBondContact O-N 2.85Å; I780-D784 HydrophobicContact CG2-CB 4.32Å; I780-D784 WeakPolarHBondContact CG2-O 3.46Å; I780-Q785 PolarHBondContact O-NE2 2.87Å; I780-F787 HydrophobicContact CD1-CD2 4.13Å; I780-F787 HydrophobicContact CD1-CE2 3.72Å
781P82Confident87.4Confident85 Ų8574.1 Ų74.155%0.55239%0.385SS*.  trans-58141.9178.9-25.434.9000112.8L779 M783 D784 Q785L779-P781 WeakPolarHBondContact O-CD 3.36Å; P781-M783 PolarHBondContact O-N 2.96Å; P781-D784 CarbonylContact O-C 3.54Å; P781-D784 WeakPolarHBondContact O-CA 3.36Å; P781-D784 PolarHBondContact O-N 2.65Å; P781-Q785 PolarHBondContact O-N 2.88Å
782E76.1Confident87.2Confident182 Ų18272.4 Ų72.485%0.8537%0.373SS*.G310 helixtrans-51.9-34.6-172.7-170.3177.5-16300114.6D784E782-D784 VanDerWaalsContact C-N 3.33Å; E782-D784 PolarHBondContact O-N 2.85Å
783M72.9Confident87.2Confident135 Ų13569.2 Ų69.267%0.66536%0.361SS*.G310 helixtrans-67.1-31.5176.9-68.4-123.8-66.900114.1P781 R853P781-M783 PolarHBondContact O-N 2.96Å; M783-R853 PolarHBondContact O-NH1 3.46Å
784D76.5Confident87.2Confident55 Ų5570.3 Ų70.329%0.29437%0.37SS..G310 helixtrans-107.25.2-177.1-65.2-41.7000112.2I780 P781 E782 R855I780-D784 HydrophobicContact CG2-CB 4.32Å; I780-D784 WeakPolarHBondContact CG2-O 3.46Å; P781-D784 CarbonylContact O-C 3.54Å; P781-D784 WeakPolarHBondContact O-CA 3.36Å; P781-D784 PolarHBondContact O-N 2.65Å; E782-D784 VanDerWaalsContact C-N 3.33Å; E782-D784 PolarHBondContact O-N 2.85Å; D784-R855 IonicContact OD1-NH2 3.42Å; D784-R855 IonicContact OD2-CZ 3.66Å; D784-R855 IonicContact OD2-NE 3.5Å; D784-R855 IonicContact OD2-NH2 3.65Å; D784-R855 PolarHBondContact OD2-NH2 3.4Å
785Q83.3Confident87.2Confident46 Ų4669.8 Ų69.822%0.21537%0.368CS..  trans-65.2135.7-176.4-179.157.3-91.700112.5A777 I780 P781 F787A777-Q785 PolarHBondContact O-NE2 2.96Å; I780-Q785 PolarHBondContact O-NE2 2.87Å; P781-Q785 PolarHBondContact O-N 2.88Å; Q785-F787 WeakPolarHBondContact CG-O 3.47Å
786I84.8Confident87.3Confident50 Ų5066.3 Ų66.326%0.25635%0.354SS..  trans-108.6-29.8-172.5-59.7173.5000111.6K846 T850I786-K846 HydrophobicContact CG2-CG 4.49Å; I786-K846 VanDerWaalsContact O-CE 3.31Å; I786-K846 WeakPolarHBondContact O-CE 3.23Å; I786-T850 HydrophobicContact CG1-CG2 4.12Å; I786-T850 HydrophobicContact CG2-CG2 4.03Å; I786-T850 WeakPolarHBondContact CG2-OG1 3.24Å
787F89.9Confident87.5Confident12 Ų1270.1 Ų70.15%0.05336%0.359CS..SBendtrans-102.7142.3-176-45-67.2000110.8F773 A777 I780 Q785 M792 L843 A847F773-F787 HydrophobicContact CE2-CZ 4.36Å; F773-F787 HydrophobicContact CZ-CE1 4.16Å; F773-F787 HydrophobicContact CZ-CE2 4.31Å; F773-F787 AromaticContact CZ-CZ 3.72Å; F773-F787 HydrophobicContact CZ-CZ 3.72Å; A777-F787 HydrophobicContact CB-CD2 3.47Å; A777-F787 VanDerWaalsContact CB-CD2 3.47Å; A777-F787 HydrophobicContact CB-CE2 3.62Å; A777-F787 HydrophobicContact CB-CG 4.42Å; I780-F787 HydrophobicContact CD1-CD2 4.13Å; I780-F787 HydrophobicContact CD1-CE2 3.72Å; Q785-F787 WeakPolarHBondContact CG-O 3.47Å; F787-M792 HydrophobicContact CB-CG 3.81Å; F787-M792 HydrophobicContact CB-SD 4.07Å; F787-L843 HydrophobicContact CD1-CB 4.12Å; F787-L843 HydrophobicContact CD1-CD2 3.96Å; F787-L843 HydrophobicContact CD1-CG 4.47Å; F787-L843 HydrophobicContact CE1-CB 3.89Å; F787-L843 WeakPolarHBondContact CE1-O 3.33Å; F787-A847 HydrophobicContact CE1-CB 4.16Å; F787-A847 HydrophobicContact CZ-CB 3.93Å
788T90.1Very high87.9Confident68 Ų6871.2 Ų71.242%0.41737%0.365SS..  trans-82.4154.1173.364.20000110.7V790 E791 M792T788-V790 PolarHBondContact O-N 2.81Å; T788-E791 WeakPolarHBondContact CB-OE2 3.42Å; T788-E791 WeakPolarHBondContact CG2-OE2 3.39Å; T788-E791 PolarHBondContact N-OE2 2.9Å; T788-E791 WeakPolarHBondContact O-CB 3.47Å; T788-E791 PolarHBondContact O-N 3.49Å; T788-E791 VanDerWaalsContact OG1-CG 3.27Å; T788-E791 WeakPolarHBondContact OG1-CG 3.24Å; T788-E791 PolarHBondContact OG1-N 2.93Å; T788-E791 PolarHBondContact OG1-OE2 3.38Å; T788-M792 PolarHBondContact O-N 2.77Å
789E87.3Confident88.2Confident107 Ų10766.8 Ų66.850%0.535%0.349SS..Hα-helixtrans-60.5-31.9178-164.857.6-140.200112.1R778 M792 T793R778-E789 IonicContact NE-OE1 2.62Å; R778-E789 IonicContact NH2-OE1 3.17Å; R778-E789 PolarHBondContact NH2-OE1 2.82Å; E789-M792 PolarHBondContact O-N 2.8Å; E789-M792 WeakPolarHBondContact OE2-CE 3.46Å; E789-T793 WeakPolarHBondContact O-CB 3.38Å; E789-T793 PolarHBondContact O-N 2.68Å; E789-T793 PolarHBondContact O-OG1 2.86Å
790V90.1Very high88.6Confident108 Ų10864.7 Ų64.766%0.65534%0.339SS*.Hα-helixtrans-64-41.6174.9-1780000111.1T788 T794T788-V790 PolarHBondContact O-N 2.81Å; V790-T794 VanDerWaalsContact O-CB 3.29Å; V790-T794 WeakPolarHBondContact O-CB 3.34Å; V790-T794 PolarHBondContact O-N 2.96Å; V790-T794 PolarHBondContact O-OG1 2.81Å
791E92.1Very high89.1Confident27 Ų2767 Ų6713%0.12635%0.348CS..Hα-helixtrans-67.9-45.5177.4-75161.5144.700111.7T788 T794 L795 Y842 L843 K846T788-E791 WeakPolarHBondContact CB-OE2 3.42Å; T788-E791 WeakPolarHBondContact CG2-OE2 3.39Å; T788-E791 PolarHBondContact N-OE2 2.9Å; T788-E791 WeakPolarHBondContact O-CB 3.47Å; T788-E791 PolarHBondContact O-N 3.49Å; T788-E791 VanDerWaalsContact OG1-CG 3.27Å; T788-E791 WeakPolarHBondContact OG1-CG 3.24Å; T788-E791 PolarHBondContact OG1-N 2.93Å; T788-E791 PolarHBondContact OG1-OE2 3.38Å; E791-T794 WeakPolarHBondContact O-CB 3.34Å; E791-T794 PolarHBondContact O-N 2.89Å; E791-L795 PolarHBondContact O-N 2.98Å; E791-Y842 HydrophobicContact CG-CE1 4.24Å; E791-Y842 WeakPolarHBondContact OE1-CE1 3.29Å; E791-Y842 PolarHBondContact OE1-OH 2.93Å; E791-L843 HydrophobicContact CB-CD2 3.81Å; E791-L843 HydrophobicContact CG-CD2 4.11Å; E791-K846 IonicContact OE1-NZ 2.66Å; E791-K846 PolarHBondContact OE1-NZ 2.62Å; E791-K846 IonicContact OE2-NZ 3.81Å; E791-K846 PolarHBondContact OE2-NZ 3.31Å
792M91.3Very high89.8Confident6 Ų663.1 Ų63.13%0.0332%0.323CS..Hα-helixtrans-65-42.3177.5-67.4-170.9-70.100111.9L774 A777 R778 F787 T788 E789 T794 L795 E796L774-M792 HydrophobicContact CD1-CB 3.89Å; L774-M792 HydrophobicContact CD1-CG 4.35Å; L774-M792 WeakPolarHBondContact CD1-O 3.37Å; A777-M792 HydrophobicContact CB-SD 3.98Å; R778-M792 HydrophobicContact CG-CE 4.45Å; R778-M792 HydrophobicContact CG-SD 3.72Å; F787-M792 HydrophobicContact CB-CG 3.81Å; F787-M792 HydrophobicContact CB-SD 4.07Å; T788-M792 PolarHBondContact O-N 2.77Å; E789-M792 PolarHBondContact O-N 2.8Å; E789-M792 WeakPolarHBondContact OE2-CE 3.46Å; M792-T794 VanDerWaalsContact C-N 3.29Å; M792-T794 PolarHBondContact O-N 3.19Å; M792-L795 PolarHBondContact O-N 3.12Å; M792-E796 WeakPolarHBondContact O-CB 3.49Å; M792-E796 PolarHBondContact O-N 2.82Å
793T92.9Very high90.7Very high66 Ų6658 Ų5841%0.40530%0.296SS..Hα-helixtrans-64.3-32.8172.7-56.40000111.9E789 K797E789-T793 WeakPolarHBondContact O-CB 3.38Å; E789-T793 PolarHBondContact O-N 2.68Å; E789-T793 PolarHBondContact O-OG1 2.86Å; T793-K797 VanDerWaalsContact O-CB 3.27Å; T793-K797 WeakPolarHBondContact O-CB 3.13Å; T793-K797 PolarHBondContact O-N 3.03Å
794T93.2Very high91.8Very high59 Ų5954.5 Ų54.536%0.36229%0.289SS..Hα-helixtrans-68.6-46.9176.3-60.40000111.1V790 E791 M792 K797 V798V790-T794 VanDerWaalsContact O-CB 3.29Å; V790-T794 WeakPolarHBondContact O-CB 3.34Å; V790-T794 PolarHBondContact O-N 2.96Å; V790-T794 PolarHBondContact O-OG1 2.81Å; E791-T794 WeakPolarHBondContact O-CB 3.34Å; E791-T794 PolarHBondContact O-N 2.89Å; M792-T794 VanDerWaalsContact C-N 3.29Å; M792-T794 PolarHBondContact O-N 3.19Å; T794-K797 WeakPolarHBondContact O-CB 3.31Å; T794-K797 PolarHBondContact O-N 2.86Å; T794-V798 WeakPolarHBondContact O-CG2 3.46Å; T794-V798 PolarHBondContact O-N 2.96Å
795L94Very high92.8Very high2 Ų254.5 Ų54.51%0.0129%0.285CS..Hα-helixtrans-62.9-44.8174.7176.660.3000111.4F773 L774 E791 M792 K797 V798 I799 L836 E839 V840 L843F773-L795 HydrophobicContact CD1-CD2 3.8Å; F773-L795 HydrophobicContact CE1-CD2 4.19Å; L774-L795 HydrophobicContact CB-CD2 4.09Å; E791-L795 PolarHBondContact O-N 2.98Å; M792-L795 PolarHBondContact O-N 3.12Å; L795-K797 VanDerWaalsContact C-N 3.3Å; L795-K797 PolarHBondContact O-N 3.33Å; L795-V798 PolarHBondContact O-N 2.82Å; L795-V798 VanDerWaalsContact O-N 3.16Å; L795-I799 HydrophobicContact CD1-CD1 3.99Å; L795-I799 HydrophobicContact CD1-CG1 4.11Å; L795-I799 HydrophobicContact CD2-CD1 4.46Å; L795-I799 HydrophobicContact CG-CD1 3.81Å; L795-I799 HydrophobicContact CG-CG1 4.39Å; L795-I799 WeakPolarHBondContact O-CG1 3.31Å; L795-I799 PolarHBondContact O-N 2.99Å; L795-L836 HydrophobicContact CD1-CD1 3.92Å; L795-E839 HydrophobicContact CD1-CB 4.1Å; L795-V840 HydrophobicContact CD1-CG2 3.76Å; L795-V840 HydrophobicContact CD2-CG2 4.37Å; L795-L843 HydrophobicContact CB-CD1 4.24Å; L795-L843 HydrophobicContact CD2-CD1 3.99Å
796E95.2Very high93.4Very high63 Ų6353 Ų5329%0.29428%0.278SS..Hα-helixtrans-55.3-45.3174.7-177.9164.5-124.100112L774 R778 M792 I799 N800L774-E796 HydrophobicContact CD2-CB 3.62Å; L774-E796 HydrophobicContact CD2-CG 4.09Å; R778-E796 IonicContact CZ-OE1 3.91Å; R778-E796 IonicContact CZ-OE2 2.66Å; R778-E796 IonicContact NH1-OE1 2.68Å; R778-E796 PolarHBondContact NH1-OE1 2.83Å; R778-E796 IonicContact NH1-OE2 3.39Å; R778-E796 PolarHBondContact NH1-OE2 2.86Å; R778-E796 IonicContact NH2-OE1 3.88Å; R778-E796 IonicContact NH2-OE2 3.67Å; R778-E796 PolarHBondContact NH2-OE2 2.92Å; M792-E796 WeakPolarHBondContact O-CB 3.49Å; M792-E796 PolarHBondContact O-N 2.82Å; E796-I799 PolarHBondContact O-N 3.23Å; E796-N800 WeakPolarHBondContact CG-ND2 3.46Å; E796-N800 WeakPolarHBondContact O-CB 3.41Å; E796-N800 VanDerWaalsContact O-CG 3.23Å; E796-N800 PolarHBondContact O-N 2.9Å; E796-N800 PolarHBondContact O-ND2 2.83Å
797K95.5Very high93.9Very high118 Ų11854.6 Ų54.651%0.51329%0.287SS..Hα-helixtrans-60.1-47.3175.6-179.4-179.7172.4-177.80111.7T793 T794 L795 N800 E801T793-K797 VanDerWaalsContact O-CB 3.27Å; T793-K797 WeakPolarHBondContact O-CB 3.13Å; T793-K797 PolarHBondContact O-N 3.03Å; T794-K797 WeakPolarHBondContact O-CB 3.31Å; T794-K797 PolarHBondContact O-N 2.86Å; L795-K797 VanDerWaalsContact C-N 3.3Å; L795-K797 PolarHBondContact O-N 3.33Å; K797-N800 PolarHBondContact O-N 3.45Å; K797-E801 WeakPolarHBondContact CE-OE1 3.17Å; K797-E801 WeakPolarHBondContact CE-OE2 3.42Å; K797-E801 HydrophobicContact CG-CG 4.23Å; K797-E801 IonicContact NZ-OE1 3.34Å; K797-E801 PolarHBondContact NZ-OE1 2.64Å; K797-E801 WeakPolarHBondContact O-CB 3.35Å; K797-E801 WeakPolarHBondContact O-CG 3.32Å; K797-E801 PolarHBondContact O-N 2.97Å
798V95.4Very high94.2Very high25 Ų2556.4 Ų56.415%0.15230%0.304CS..Hα-helixtrans-67.2-36.8-179.1175.20000111.8T794 L795 T802 L836 E839T794-V798 WeakPolarHBondContact O-CG2 3.46Å; T794-V798 PolarHBondContact O-N 2.96Å; L795-V798 PolarHBondContact O-N 2.82Å; L795-V798 VanDerWaalsContact O-N 3.16Å; V798-T802 WeakPolarHBondContact O-CB 3.25Å; V798-T802 PolarHBondContact O-N 3.41Å; V798-T802 PolarHBondContact O-OG1 2.99Å; V798-L836 HydrophobicContact CG1-CB 4.28Å; V798-L836 HydrophobicContact CG1-CD1 4.02Å; V798-E839 HydrophobicContact CG2-CG 4.29Å
799I96.1Very high94.4Very high6 Ų653.8 Ų53.83%0.03129%0.288CS..Hα-helixtrans-59.7-52.4170.6-69.7165.3000110L767 L774 L795 E796 T802 W803 L836L767-I799 HydrophobicContact CD2-CG2 4.34Å; L774-I799 HydrophobicContact CB-CD1 4.32Å; L774-I799 HydrophobicContact CD2-CD1 3.99Å; L795-I799 HydrophobicContact CD1-CD1 3.99Å; L795-I799 HydrophobicContact CD1-CG1 4.11Å; L795-I799 HydrophobicContact CD2-CD1 4.46Å; L795-I799 HydrophobicContact CG-CD1 3.81Å; L795-I799 HydrophobicContact CG-CG1 4.39Å; L795-I799 WeakPolarHBondContact O-CG1 3.31Å; L795-I799 PolarHBondContact O-N 2.99Å; E796-I799 PolarHBondContact O-N 3.23Å; I799-T802 PolarHBondContact O-N 3.34Å; I799-T802 VanDerWaalsContact O-N 3.15Å; I799-W803 PolarHBondContact O-N 3.44Å; I799-L836 HydrophobicContact CG1-CD1 3.67Å
800N95.8Very high94.7Very high90 Ų9051.4 Ų51.448%0.48128%0.278SS..Hα-helixtrans-66.8-41.8-176.3-71.7-26000112.8E796 K797 T802 W803 A804E796-N800 WeakPolarHBondContact CG-ND2 3.46Å; E796-N800 WeakPolarHBondContact O-CB 3.41Å; E796-N800 VanDerWaalsContact O-CG 3.23Å; E796-N800 PolarHBondContact O-N 2.9Å; E796-N800 PolarHBondContact O-ND2 2.83Å; K797-N800 PolarHBondContact O-N 3.45Å; N800-T802 PolarHBondContact O-N 2.56Å; N800-W803 PolarHBondContact O-N 2.88Å; N800-A804 WeakPolarHBondContact O-CB 3.36Å; N800-A804 PolarHBondContact O-N 2.88Å
801E95.8Very high94.9Very high97 Ų9748.7 Ų48.745%0.45327%0.267SS..Hα-helixtrans-67.6-20.7173.9-73.8-176.4159.200113K797 W805 K832K797-E801 WeakPolarHBondContact CE-OE1 3.17Å; K797-E801 WeakPolarHBondContact CE-OE2 3.42Å; K797-E801 HydrophobicContact CG-CG 4.23Å; K797-E801 IonicContact NZ-OE1 3.34Å; K797-E801 PolarHBondContact NZ-OE1 2.64Å; K797-E801 WeakPolarHBondContact O-CB 3.35Å; K797-E801 WeakPolarHBondContact O-CG 3.32Å; K797-E801 PolarHBondContact O-N 2.97Å; E801-W805 WeakPolarHBondContact O-CB 3.32Å; E801-W805 PolarHBondContact O-N 3.48Å; E801-K832 PolarHBondContact O-NZ 2.88Å; E801-K832 VanDerWaalsContact O-NZ 3.11Å
802T96.5Very high95Very high4 Ų452.3 Ų52.33%0.02528%0.284CS..Hα-helixtrans-87-43.2175.7-60.10000111.4L763 L767 V798 I799 N800 W805 K806 K832L763-T802 HydrophobicContact CD1-CG2 3.81Å; L767-T802 HydrophobicContact CD1-CG2 4.34Å; L767-T802 HydrophobicContact CD2-CG2 3.89Å; L767-T802 HydrophobicContact CG-CG2 4.4Å; V798-T802 WeakPolarHBondContact O-CB 3.25Å; V798-T802 PolarHBondContact O-N 3.41Å; V798-T802 PolarHBondContact O-OG1 2.99Å; I799-T802 PolarHBondContact O-N 3.34Å; I799-T802 VanDerWaalsContact O-N 3.15Å; N800-T802 PolarHBondContact O-N 2.56Å; T802-W805 PolarHBondContact O-N 2.76Å; T802-K806 VanDerWaalsContact O-CB 3.28Å; T802-K806 WeakPolarHBondContact O-CB 3.29Å; T802-K806 PolarHBondContact O-N 2.77Å; T802-K832 HydrophobicContact CG2-CB 4.11Å; T802-K832 HydrophobicContact CG2-CD 4.14Å
803W96.5Very high95.2Very high73 Ų7352.6 Ų52.628%0.27729%0.285SS..Hα-helixtrans-58.9-48.9169.9-95.8122000112.3D764 L767 I799 N800 W805 K806 N807D764-W803 WeakPolarHBondContact OD1-CH2 3.5Å; L767-W803 HydrophobicContact CB-CZ2 4.26Å; L767-W803 HydrophobicContact CD1-CD2 3.99Å; L767-W803 HydrophobicContact CD1-CE3 4.38Å; L767-W803 HydrophobicContact CD1-CG 4.33Å; L767-W803 HydrophobicContact CD1-CZ2 4.24Å; L767-W803 HydrophobicContact CD2-CG 4.25Å; I799-W803 PolarHBondContact O-N 3.44Å; N800-W803 PolarHBondContact O-N 2.88Å; W803-W805 PolarHBondContact O-N 2.81Å; W803-K806 HydrophobicContact CE3-CD 4.3Å; W803-K806 HydrophobicContact CZ3-CD 4.1Å; W803-K806 PolarHBondContact O-N 2.89Å; W803-N807 WeakPolarHBondContact O-CB 3.39Å; W803-N807 VanDerWaalsContact O-CG 3.27Å; W803-N807 PolarHBondContact O-N 3.31Å
804A96Very high95.1Very high63 Ų6353.7 Ų53.752%0.52130%0.301SS..Hα-helixtrans-61.9-43.4179.300000111.7N800 A808N800-A804 WeakPolarHBondContact O-CB 3.36Å; N800-A804 PolarHBondContact O-N 2.88Å; A804-A808 WeakPolarHBondContact O-CB 3.34Å; A804-A808 PolarHBondContact O-N 3.04Å
805W96.9Very high95.2Very high54 Ų5458.4 Ų58.421%0.20532%0.316CS..Hα-helixtrans-62.2-51.2174.117079.3000112.1L763 E801 T802 W803 N807 A808 T809 L824 D828 I829 K832L763-W805 HydrophobicContact CD2-CZ3 4.06Å; E801-W805 WeakPolarHBondContact O-CB 3.32Å; E801-W805 PolarHBondContact O-N 3.48Å; T802-W805 PolarHBondContact O-N 2.76Å; W803-W805 PolarHBondContact O-N 2.81Å; W805-N807 VanDerWaalsContact C-N 3.32Å; W805-N807 PolarHBondContact O-N 3.12Å; W805-A808 PolarHBondContact O-N 2.99Å; W805-T809 PolarHBondContact NE1-OG1 3.16Å; W805-T809 WeakPolarHBondContact O-CB 3.25Å; W805-T809 PolarHBondContact O-N 3.41Å; W805-T809 PolarHBondContact O-OG1 2.74Å; W805-L824 HydrophobicContact CH2-CD1 4.46Å; W805-D828 HydrophobicContact CH2-CB 4.41Å; W805-D828 HydrophobicContact CZ2-CB 3.86Å; W805-I829 HydrophobicContact CH2-CB 4.46Å; W805-I829 HydrophobicContact CH2-CG1 3.88Å; W805-I829 HydrophobicContact CZ3-CG1 4.48Å; W805-K832 HydrophobicContact CD2-CD 4.05Å; W805-K832 HydrophobicContact CD2-CG 3.95Å; W805-K832 HydrophobicContact CE3-CB 4.31Å; W805-K832 HydrophobicContact CE3-CD 3.93Å; W805-K832 HydrophobicContact CE3-CG 3.63Å; W805-K832 HydrophobicContact CG-CD 4.34Å; W805-K832 VanDerWaalsContact CG-CE 3.45Å; W805-K832 HydrophobicContact CH2-CG 4.15Å; W805-K832 HydrophobicContact CZ2-CG 4.43Å; W805-K832 HydrophobicContact CZ3-CB 4.12Å; W805-K832 HydrophobicContact CZ3-CG 3.75Å
806K96.1Very high95.1Very high16 Ų1660.8 Ų60.87%0.0733%0.329CS..Hα-helixtrans-56.2-49-178-173.2-148.5179.7-156.70110.5L763 D764 L767 T802 W803 L810L763-K806 HydrophobicContact CD2-CB 4.34Å; L763-K806 HydrophobicContact CD2-CD 4.26Å; L763-K806 HydrophobicContact CD2-CG 3.95Å; D764-K806 IonicContact OD1-NZ 3.77Å; D764-K806 PolarHBondContact OD1-NZ 3.41Å; D764-K806 IonicContact OD2-NZ 3.68Å; D764-K806 PolarHBondContact OD2-NZ 3.45Å; L767-K806 HydrophobicContact CD1-CD 4.44Å; T802-K806 VanDerWaalsContact O-CB 3.28Å; T802-K806 WeakPolarHBondContact O-CB 3.29Å; T802-K806 PolarHBondContact O-N 2.77Å; W803-K806 HydrophobicContact CE3-CD 4.3Å; W803-K806 HydrophobicContact CZ3-CD 4.1Å; W803-K806 PolarHBondContact O-N 2.89Å; K806-L810 HydrophobicContact CD-CD1 4.28Å; K806-L810 HydrophobicContact CG-CD1 3.99Å; K806-L810 VanDerWaalsContact O-CB 3.29Å; K806-L810 WeakPolarHBondContact O-CB 3.44Å; K806-L810 VanDerWaalsContact O-CG 3.29Å; K806-L810 WeakPolarHBondContact O-CG 3.38Å; K806-L810 PolarHBondContact O-N 3.31Å
807N95.3Very high95Very high83 Ų8360.8 Ų60.844%0.44433%0.334SS..Hα-helixtrans-69.1-38.5-177.9-66.4-9.8000112W803 W805 A811W803-N807 WeakPolarHBondContact O-CB 3.39Å; W803-N807 VanDerWaalsContact O-CG 3.27Å; W803-N807 PolarHBondContact O-N 3.31Å; W805-N807 VanDerWaalsContact C-N 3.32Å; W805-N807 PolarHBondContact O-N 3.12Å; N807-A811 VanDerWaalsContact O-CB 3.26Å; N807-A811 WeakPolarHBondContact O-CB 3.49Å; N807-A811 PolarHBondContact O-N 3.5Å
808A95.6Very high94.7Very high49 Ų4956.4 Ų56.441%0.40532%0.32SS..Hα-helixtrans-65.2-51.117500000111.9A804 W805 L810 A811 E812A804-A808 WeakPolarHBondContact O-CB 3.34Å; A804-A808 PolarHBondContact O-N 3.04Å; W805-A808 PolarHBondContact O-N 2.99Å; A808-L810 PolarHBondContact O-N 3.39Å; A808-A811 CarbonylContact O-C 3.59Å; A808-A811 PolarHBondContact O-N 2.95Å; A808-A811 VanDerWaalsContact O-N 3.11Å; A808-E812 WeakPolarHBondContact O-CG 3.36Å; A808-E812 PolarHBondContact O-N 3.01Å
809T94.7Very high94.5Very high14 Ų1457.5 Ų57.59%0.08633%0.327CS..Hα-helixtrans-68.2-32.2-178.4-60.60000112.3W805 E812 Q813 L824W805-T809 PolarHBondContact NE1-OG1 3.16Å; W805-T809 WeakPolarHBondContact O-CB 3.25Å; W805-T809 PolarHBondContact O-N 3.41Å; W805-T809 PolarHBondContact O-OG1 2.74Å; T809-E812 PolarHBondContact O-N 3.37Å; T809-Q813 VanDerWaalsContact O-CB 3.25Å; T809-Q813 WeakPolarHBondContact O-CB 3.4Å; T809-Q813 PolarHBondContact O-N 3.41Å; T809-L824 HydrophobicContact CG2-CB 4.1Å; T809-L824 HydrophobicContact CG2-CD1 3.9Å
810L94.8Very high94.3Very high57 Ų5762 Ų6230%0.29835%0.347SS..Hα-helixtrans-64-44.6167.7-78.9168.9000112L760 K806 A808 E812 Q813 A814 L824L760-L810 HydrophobicContact CD1-CD2 4.09Å; L760-L810 HydrophobicContact CD2-CD2 4.44Å; K806-L810 HydrophobicContact CD-CD1 4.28Å; K806-L810 HydrophobicContact CG-CD1 3.99Å; K806-L810 VanDerWaalsContact O-CB 3.29Å; K806-L810 WeakPolarHBondContact O-CB 3.44Å; K806-L810 VanDerWaalsContact O-CG 3.29Å; K806-L810 WeakPolarHBondContact O-CG 3.38Å; K806-L810 PolarHBondContact O-N 3.31Å; A808-L810 PolarHBondContact O-N 3.39Å; L810-E812 VanDerWaalsContact C-N 3.25Å; L810-E812 PolarHBondContact O-N 3.25Å; L810-Q813 PolarHBondContact O-N 3.32Å; L810-A814 WeakPolarHBondContact O-CB 3.36Å; L810-A814 PolarHBondContact O-N 3.25Å; L810-L824 HydrophobicContact CD2-CD2 3.85Å
811A94.1Very high94.2Very high50 Ų5064.4 Ų64.441%0.41335%0.354SS..Hα-helixtrans-71.7-15.8177.900000113.9N807 A808 K815N807-A811 VanDerWaalsContact O-CB 3.26Å; N807-A811 WeakPolarHBondContact O-CB 3.49Å; N807-A811 PolarHBondContact O-N 3.5Å; A808-A811 CarbonylContact O-C 3.59Å; A808-A811 PolarHBondContact O-N 2.95Å; A808-A811 VanDerWaalsContact O-N 3.11Å; A811-K815 WeakPolarHBondContact O-CD 3.2Å; A811-K815 WeakPolarHBondContact O-CE 3.38Å; A811-K815 WeakPolarHBondContact O-CG 3.31Å; A811-K815 PolarHBondContact O-NZ 2.81Å
812E94.3Very high94.1Very high103 Ų10360.1 Ų60.148%0.48133%0.334SS..Hα-helixtrans-83.8-46.5166.7-72.3175.9162.700110.9A808 T809 L810 A814 K815 V823A808-E812 WeakPolarHBondContact O-CG 3.36Å; A808-E812 PolarHBondContact O-N 3.01Å; T809-E812 PolarHBondContact O-N 3.37Å; L810-E812 VanDerWaalsContact C-N 3.25Å; L810-E812 PolarHBondContact O-N 3.25Å; E812-A814 VanDerWaalsContact C-N 3.28Å; E812-A814 PolarHBondContact O-N 3.19Å; E812-K815 WeakPolarHBondContact O-CB 3.43Å; E812-K815 PolarHBondContact O-N 2.84Å; E812-V823 HydrophobicContact CB-CG2 4.12Å
813Q93.9Very high94Very high12 Ų1262.9 Ų62.96%0.05635%0.351CS..Hα-helixtrans-60-36.2178.2-175.856.67400112.8W756 T809 L810 K815 L816 V823 L824W756-Q813 HydrophobicContact CH2-CG 3.76Å; W756-Q813 HydrophobicContact CZ2-CG 4.35Å; W756-Q813 HydrophobicContact CZ3-CG 4.19Å; T809-Q813 VanDerWaalsContact O-CB 3.25Å; T809-Q813 WeakPolarHBondContact O-CB 3.4Å; T809-Q813 PolarHBondContact O-N 3.41Å; L810-Q813 PolarHBondContact O-N 3.32Å; Q813-K815 PolarHBondContact O-N 2.76Å; Q813-L816 PolarHBondContact O-N 3.34Å; Q813-V823 HydrophobicContact CB-CG2 4.01Å; Q813-L824 HydrophobicContact CB-CB 4Å; Q813-L824 HydrophobicContact CG-CB 3.89Å
814A92.4Very high93.9Very high90 Ų9059.5 Ų59.574%0.74434%0.338SS*.THydrogen-bonded Turntrans-68.3-9.6176.900000114.5L810 E812L810-A814 WeakPolarHBondContact O-CB 3.36Å; L810-A814 PolarHBondContact O-N 3.25Å; E812-A814 VanDerWaalsContact C-N 3.28Å; E812-A814 PolarHBondContact O-N 3.19Å
815K93.6Very high93.9Very high157 Ų15758.3 Ų58.368%0.68332%0.323SS*.THydrogen-bonded Turntrans-94.4-12.6175.6-62.5165.4-174.4140.40113.1A811 E812 Q813A811-K815 WeakPolarHBondContact O-CD 3.2Å; A811-K815 WeakPolarHBondContact O-CE 3.38Å; A811-K815 WeakPolarHBondContact O-CG 3.31Å; A811-K815 PolarHBondContact O-NZ 2.81Å; E812-K815 WeakPolarHBondContact O-CB 3.43Å; E812-K815 PolarHBondContact O-N 2.84Å; Q813-K815 PolarHBondContact O-N 2.76Å
816L92.9Very high93.8Very high52 Ų5255.9 Ų55.927%0.27231%0.314SS..SBendtrans-95.6136.8-175.9-58.6-179.5000110.8Q813 V823Q813-L816 PolarHBondContact O-N 3.34Å; L816-V823 HydrophobicContact CD1-CB 4.36Å; L816-V823 HydrophobicContact CD1-CG1 3.75Å; L816-V823 HydrophobicContact CD1-CG2 3.84Å
817P92.5Very high93.8Very high64 Ų6462.3 Ų62.342%0.41634%0.342SS..  trans-54149.9169-24.934.1000112.2T819 E820P817-T819 WeakPolarHBondContact CB-OG1 3.4Å; P817-T819 PolarHBondContact O-N 2.91Å; P817-T819 VanDerWaalsContact O-N 3.15Å; P817-E820 HydrophobicContact CB-CG 4.32Å; P817-E820 HydrophobicContact CG-CG 4.2Å; P817-E820 PolarHBondContact O-N 3.04Å
818A90.4Very high93.8Very high25 Ų2561.6 Ų61.621%0.20734%0.338CS..THydrogen-bonded Turntrans-63.3-20.8176.100000113.6E699 V700E699-A818 HydrophobicContact CG-CB 4.23Å; E699-A818 VanDerWaalsContact O-CB 3.24Å; E699-A818 WeakPolarHBondContact O-CB 3.39Å; V700-A818 WeakPolarHBondContact CA-O 3.37Å; V700-A818 WeakPolarHBondContact CB-O 3.31Å
819T91.4Very high93.8Very high48 Ų4859.2 Ų59.229%0.29432%0.319SS..THydrogen-bonded Turntrans-78.4-15173.252.30000114.2T702 R749 P817T702-T819 HydrophobicContact CG2-CG2 4.01Å; R749-T819 WeakPolarHBondContact CD-O 3.38Å; R749-T819 PolarHBondContact NH1-O 2.78Å; P817-T819 WeakPolarHBondContact CB-OG1 3.4Å; P817-T819 PolarHBondContact O-N 2.91Å; P817-T819 VanDerWaalsContact O-N 3.15Å
820E91.8Very high93.9Very high100 Ų10062.1 Ų62.147%0.46733%0.332SS..SBendtrans-84.2165.5176.8-74.5-167.5-15800112.5R749 P817R749-E820 WeakPolarHBondContact CD-O 3.4Å; P817-E820 HydrophobicContact CB-CG 4.32Å; P817-E820 HydrophobicContact CG-CG 4.2Å; P817-E820 PolarHBondContact O-N 3.04Å
821K92.2Very high93.9Very high141 Ų14161.8 Ų61.861%0.61334%0.337SS*.PPolyproline II helixtrans-69.8128.4175.8-172.5-168.2172.1-170.70109F748F748-K821 HydrophobicContact CD1-CG 4.37Å; F748-K821 HydrophobicContact CE1-CD 4.4Å; F748-K821 HydrophobicContact CE1-CG 3.87Å
822P93.9Very high94Very high7 Ų761.9 Ų61.95%0.04533%0.328CS..PPolyproline II helixtrans-63.1149177.724.2-33.9000113.6F748 E752 W756 L825F748-P822 HydrophobicContact CD1-CG 4.49Å; F748-P822 HydrophobicContact CE1-CG 3.86Å; E752-P822 HydrophobicContact CB-CG 4.05Å; E752-P822 HydrophobicContact CG-CG 4.01Å; W756-P822 HydrophobicContact CH2-CB 4.02Å; W756-P822 HydrophobicContact CZ2-CB 3.55Å; W756-P822 HydrophobicContact CZ2-CG 4.32Å; P822-L825 HydrophobicContact CB-CD2 4.48Å; P822-L825 HydrophobicContact CG-CD2 4.24Å; P822-L825 WeakPolarHBondContact O-CD2 3.23Å
823V94.4Very high94.1Very high63 Ų6359.2 Ų59.238%0.38232%0.316SS..SBendtrans-101-25.6168.5-67.10000111.8E812 Q813 L816 L825E812-V823 HydrophobicContact CB-CG2 4.12Å; Q813-V823 HydrophobicContact CB-CG2 4.01Å; L816-V823 HydrophobicContact CD1-CB 4.36Å; L816-V823 HydrophobicContact CD1-CG1 3.75Å; L816-V823 HydrophobicContact CD1-CG2 3.84Å; V823-L825 PolarHBondContact O-N 2.91Å; V823-L825 VanDerWaalsContact O-N 3.17Å
824L94.5Very high94.2Very high1 Ų164.8 Ų64.81%0.00534%0.344CS..SBendtrans-7798165.2-17869.7000108.2W756 L760 W805 T809 L810 Q813 I829W756-L824 HydrophobicContact CD2-CD2 3.9Å; W756-L824 HydrophobicContact CE3-CD2 4.44Å; W756-L824 HydrophobicContact CG-CD2 4.01Å; W756-L824 HydrophobicContact CZ2-CB 4.15Å; W756-L824 HydrophobicContact CZ2-CD2 4.49Å; W756-L824 WeakPolarHBondContact CZ2-O 3.34Å; W756-L824 PolarHBondContact NE1-O 2.78Å; L760-L824 HydrophobicContact CD1-CD2 4.16Å; L760-L824 HydrophobicContact CD2-CD2 4.32Å; W805-L824 HydrophobicContact CH2-CD1 4.46Å; T809-L824 HydrophobicContact CG2-CB 4.1Å; T809-L824 HydrophobicContact CG2-CD1 3.9Å; L810-L824 HydrophobicContact CD2-CD2 3.85Å; Q813-L824 HydrophobicContact CB-CB 4Å; Q813-L824 HydrophobicContact CG-CB 3.89Å; L824-I829 HydrophobicContact CD1-CD1 4.01Å; L824-I829 HydrophobicContact CD1-CG1 4.09Å; L824-I829 HydrophobicContact CD2-CD1 4.47Å; L824-I829 HydrophobicContact CG-CD1 4.2Å
825L96.3Very high94.3Very high39 Ų3962.1 Ų62.120%0.20432%0.322CS..  trans-96.9130.7177.7-58.6-172.9000111.1F748 P822 V823 K827 D828 I829F748-L825 HydrophobicContact CE1-CD2 4.36Å; F748-L825 HydrophobicContact CZ-CD2 3.82Å; P822-L825 HydrophobicContact CB-CD2 4.48Å; P822-L825 HydrophobicContact CG-CD2 4.24Å; P822-L825 WeakPolarHBondContact O-CD2 3.23Å; V823-L825 PolarHBondContact O-N 2.91Å; V823-L825 VanDerWaalsContact O-N 3.17Å; L825-K827 PolarHBondContact O-N 3.48Å; L825-K827 VanDerWaalsContact O-N 3.14Å; L825-D828 HydrophobicContact CB-CB 4.41Å; L825-D828 PolarHBondContact O-N 3.41Å; L825-I829 PolarHBondContact O-N 3.36Å; L825-I829 VanDerWaalsContact O-N 3.17Å
826S94.6Very high94.3Very high2 Ų254.6 Ų54.61%0.01429%0.289CS..Hα-helixtrans-59.1-28.5-179.1-68.80000112.4E752 R759 E830E752-S826 PolarHBondContact OE1-N 2.7Å; E752-S826 WeakPolarHBondContact OE2-CB 3.32Å; E752-S826 PolarHBondContact OE2-N 3.33Å; E752-S826 PolarHBondContact OE2-OG 3.15Å; R759-S826 VanDerWaalsContact NH1-C 3.25Å; R759-S826 PolarHBondContact NH1-O 2.86Å; S826-E830 PolarHBondContact O-N 3.23Å
827K95.4Very high94.4Very high151 Ų15155 Ų5566%0.65729%0.291SS*.Hα-helixtrans-70.2-34.4172.7177.8178.6173.4-178.50113.5L825 E830 A831L825-K827 PolarHBondContact O-N 3.48Å; L825-K827 VanDerWaalsContact O-N 3.14Å; K827-E830 WeakPolarHBondContact CA-OE2 3.37Å; K827-E830 PolarHBondContact O-N 2.67Å; K827-A831 WeakPolarHBondContact O-CB 3.17Å; K827-A831 PolarHBondContact O-N 2.66Å
828D96.2Very high94.5Very high68 Ų6859.5 Ų59.536%0.36430%0.3SS..Hα-helixtrans-78.3-29.3-179.6-63.3-25.9000110.4W805 L825 A831 K832W805-D828 HydrophobicContact CH2-CB 4.41Å; W805-D828 HydrophobicContact CZ2-CB 3.86Å; L825-D828 HydrophobicContact CB-CB 4.41Å; L825-D828 PolarHBondContact O-N 3.41Å; D828-A831 PolarHBondContact O-N 3.3Å; D828-K832 WeakPolarHBondContact O-CB 3.38Å; D828-K832 VanDerWaalsContact O-CG 3.3Å; D828-K832 WeakPolarHBondContact O-CG 3.13Å; D828-K832 PolarHBondContact O-N 2.67Å
829I96.1Very high94.6Very high0 Ų059.9 Ų59.90%030%0.297CS..Hα-helixtrans-59.3-52165-58172.2000110.4R759 L760 L763 W805 L824 L825 A831 K832 M833R759-I829 HydrophobicContact CB-CD1 4.1Å; R759-I829 HydrophobicContact CB-CG2 3.97Å; L760-I829 HydrophobicContact CD2-CD1 3.97Å; L760-I829 HydrophobicContact CG-CD1 4.25Å; L763-I829 HydrophobicContact CB-CG2 4.11Å; L763-I829 HydrophobicContact CD2-CG2 4.12Å; W805-I829 HydrophobicContact CH2-CB 4.46Å; W805-I829 HydrophobicContact CH2-CG1 3.88Å; W805-I829 HydrophobicContact CZ3-CG1 4.48Å; L824-I829 HydrophobicContact CD1-CD1 4.01Å; L824-I829 HydrophobicContact CD1-CG1 4.09Å; L824-I829 HydrophobicContact CD2-CD1 4.47Å; L824-I829 HydrophobicContact CG-CD1 4.2Å; L825-I829 PolarHBondContact O-N 3.36Å; L825-I829 VanDerWaalsContact O-N 3.17Å; I829-A831 VanDerWaalsContact C-N 3.33Å; I829-A831 PolarHBondContact O-N 3.23Å; I829-K832 PolarHBondContact O-N 3.03Å; I829-K832 VanDerWaalsContact O-N 3.14Å; I829-M833 HydrophobicContact CG2-CG 4.37Å; I829-M833 HydrophobicContact CG2-SD 3.91Å; I829-M833 WeakPolarHBondContact O-CG 3.27Å; I829-M833 PolarHBondContact O-N 3.33Å
830E95.4Very high94.7Very high75 Ų7557.7 Ų57.735%0.3528%0.284SS..Hα-helixtrans-56.7-43.7175.8-77.7168151.500112.4R759 S826 K827 K832 M833 M834R759-E830 IonicContact CZ-OE1 3.63Å; R759-E830 IonicContact CZ-OE2 3.99Å; R759-E830 IonicContact NH1-OE1 3.59Å; R759-E830 PolarHBondContact NH1-OE1 3.45Å; R759-E830 IonicContact NH1-OE2 3.78Å; R759-E830 PolarHBondContact NH1-OE2 2.88Å; R759-E830 IonicContact NH2-OE1 2.76Å; R759-E830 PolarHBondContact NH2-OE1 2.77Å; R759-E830 IonicContact NH2-OE2 2.84Å; S826-E830 PolarHBondContact O-N 3.23Å; K827-E830 WeakPolarHBondContact CA-OE2 3.37Å; K827-E830 PolarHBondContact O-N 2.67Å; E830-K832 VanDerWaalsContact C-N 3.29Å; E830-K832 PolarHBondContact O-N 3.05Å; E830-M833 PolarHBondContact O-N 2.89Å; E830-M834 HydrophobicContact CB-CE 4.26Å; E830-M834 WeakPolarHBondContact O-CB 3.35Å; E830-M834 WeakPolarHBondContact O-CE 3.35Å; E830-M834 WeakPolarHBondContact O-CG 3.47Å; E830-M834 PolarHBondContact O-N 3.11Å
831A96.1Very high94.7Very high49 Ų4956.2 Ų56.241%0.40528%0.277SS..Hα-helixtrans-61.7-36.8178.200000112.6K827 D828 I829 A835K827-A831 WeakPolarHBondContact O-CB 3.17Å; K827-A831 PolarHBondContact O-N 2.66Å; D828-A831 PolarHBondContact O-N 3.3Å; I829-A831 VanDerWaalsContact C-N 3.33Å; I829-A831 PolarHBondContact O-N 3.23Å; A831-A835 WeakPolarHBondContact O-CB 3.38Å; A831-A835 PolarHBondContact O-N 3.13Å; A831-A835 VanDerWaalsContact O-N 3.13Å
832K96.4Very high94.8Very high53 Ų5355.6 Ų55.623%0.2327%0.272CS..Hα-helixtrans-72.7-41.7175.3-74.5-84.3-176.71690112.2E801 T802 W805 D828 I829 E830 A835 L836E801-K832 PolarHBondContact O-NZ 2.88Å; E801-K832 VanDerWaalsContact O-NZ 3.11Å; T802-K832 HydrophobicContact CG2-CB 4.11Å; T802-K832 HydrophobicContact CG2-CD 4.14Å; W805-K832 HydrophobicContact CD2-CD 4.05Å; W805-K832 HydrophobicContact CD2-CG 3.95Å; W805-K832 HydrophobicContact CE3-CB 4.31Å; W805-K832 HydrophobicContact CE3-CD 3.93Å; W805-K832 HydrophobicContact CE3-CG 3.63Å; W805-K832 HydrophobicContact CG-CD 4.34Å; W805-K832 VanDerWaalsContact CG-CE 3.45Å; W805-K832 HydrophobicContact CH2-CG 4.15Å; W805-K832 HydrophobicContact CZ2-CG 4.43Å; W805-K832 HydrophobicContact CZ3-CB 4.12Å; W805-K832 HydrophobicContact CZ3-CG 3.75Å; D828-K832 WeakPolarHBondContact O-CB 3.38Å; D828-K832 VanDerWaalsContact O-CG 3.3Å; D828-K832 WeakPolarHBondContact O-CG 3.13Å; D828-K832 PolarHBondContact O-N 2.67Å; I829-K832 PolarHBondContact O-N 3.03Å; I829-K832 VanDerWaalsContact O-N 3.14Å; E830-K832 VanDerWaalsContact C-N 3.29Å; E830-K832 PolarHBondContact O-N 3.05Å; K832-A835 PolarHBondContact O-N 3.27Å; K832-L836 WeakPolarHBondContact O-CB 3.45Å; K832-L836 PolarHBondContact O-N 2.94Å
833M95.9Very high94.7Very high46 Ų4655.5 Ų55.523%0.22727%0.271CS..Hα-helixtrans-59.6-49.5173.8-68.9171.468.500111.5A762 L763 L766 I829 E830 A835 L836 D837A762-M833 HydrophobicContact CB-CE 3.57Å; A762-M833 HydrophobicContact CB-SD 4.39Å; L763-M833 HydrophobicContact CB-CG 4.02Å; L763-M833 HydrophobicContact CB-SD 4.27Å; L763-M833 HydrophobicContact CD1-CG 3.77Å; L763-M833 HydrophobicContact CG-CG 4.46Å; L766-M833 HydrophobicContact CD2-CB 4.02Å; L766-M833 HydrophobicContact CD2-CG 4.33Å; L766-M833 WeakPolarHBondContact CD2-O 3.31Å; I829-M833 HydrophobicContact CG2-CG 4.37Å; I829-M833 HydrophobicContact CG2-SD 3.91Å; I829-M833 WeakPolarHBondContact O-CG 3.27Å; I829-M833 PolarHBondContact O-N 3.33Å; E830-M833 PolarHBondContact O-N 2.89Å; M833-A835 VanDerWaalsContact C-N 3.31Å; M833-A835 PolarHBondContact O-N 3.01Å; M833-L836 PolarHBondContact O-N 2.84Å; M833-D837 PolarHBondContact O-N 3.44Å
834M95.6Very high94.4Very high129 Ų12954.6 Ų54.664%0.63526%0.264SS*.Hα-helixtrans-62.2-35.5177.4-74.6-174.7-76.200113.1E830 R838E830-M834 HydrophobicContact CB-CE 4.26Å; E830-M834 WeakPolarHBondContact O-CB 3.35Å; E830-M834 WeakPolarHBondContact O-CE 3.35Å; E830-M834 WeakPolarHBondContact O-CG 3.47Å; E830-M834 PolarHBondContact O-N 3.11Å; M834-R838 WeakPolarHBondContact O-CB 3.42Å; M834-R838 PolarHBondContact O-N 2.79Å
835A94.1Very high94.2Very high34 Ų3457.6 Ų57.628%0.28128%0.28SS..Hα-helixtrans-68-37.8176.200000112.3A831 K832 M833A831-A835 WeakPolarHBondContact O-CB 3.38Å; A831-A835 PolarHBondContact O-N 3.13Å; A831-A835 VanDerWaalsContact O-N 3.13Å; K832-A835 PolarHBondContact O-N 3.27Å; M833-A835 VanDerWaalsContact C-N 3.31Å; M833-A835 PolarHBondContact O-N 3.01Å
836L94Very high93.8Very high0 Ų058.6 Ų58.60%028%0.283CS..Hα-helixtrans-76.5-49.3-179.8178.858.7000112.4L766 L767 S770 L795 V798 I799 K832 M833 R838 E839 V840L766-L836 HydrophobicContact CD2-CB 4.16Å; L766-L836 HydrophobicContact CD2-CD2 4.09Å; L766-L836 HydrophobicContact CD2-CG 4.2Å; L766-L836 HydrophobicContact CG-CD2 3.88Å; L766-L836 HydrophobicContact CG-CG 4.16Å; L767-L836 HydrophobicContact CD2-CD2 3.65Å; L767-L836 HydrophobicContact CG-CD2 3.99Å; S770-L836 WeakPolarHBondContact OG-CG 3.29Å; L795-L836 HydrophobicContact CD1-CD1 3.92Å; V798-L836 HydrophobicContact CG1-CB 4.28Å; V798-L836 HydrophobicContact CG1-CD1 4.02Å; I799-L836 HydrophobicContact CG1-CD1 3.67Å; K832-L836 WeakPolarHBondContact O-CB 3.45Å; K832-L836 PolarHBondContact O-N 2.94Å; M833-L836 PolarHBondContact O-N 2.84Å; L836-R838 VanDerWaalsContact C-N 3.29Å; L836-R838 PolarHBondContact O-N 2.65Å; L836-E839 PolarHBondContact O-N 3.31Å; L836-V840 PolarHBondContact O-N 2.66Å
837D94.4Very high93.3Very high60 Ų6060 Ų6032%0.32130%0.295SS..Hα-helixtrans-58.9-40.2178.5176.369.3000111.3L766 M833 E839 V840 Q841L766-D837 HydrophobicContact CD1-CB 4.26Å; L766-D837 HydrophobicContact CD2-CB 4.17Å; M833-D837 PolarHBondContact O-N 3.44Å; D837-E839 VanDerWaalsContact C-N 3.29Å; D837-E839 PolarHBondContact O-N 3.24Å; D837-V840 CarbonylContact O-C 3.26Å; D837-V840 PolarHBondContact O-N 3.45Å; D837-Q841 WeakPolarHBondContact O-CG 3.43Å; D837-Q841 PolarHBondContact O-N 3.44Å; D837-Q841 WeakPolarHBondContact OD1-CG 3.41Å; D837-Q841 PolarHBondContact OD1-NE2 2.79Å; D837-Q841 WeakPolarHBondContact OD2-CG 3.47Å
838R94.9Very high92.9Very high159 Ų15959.4 Ų59.460%0.629%0.292SS*.Hα-helixtrans-52.9-44.4177.3-173.7-171.571.5-153.1-1.5113.1M834 L836 Y842M834-R838 WeakPolarHBondContact O-CB 3.42Å; M834-R838 PolarHBondContact O-N 2.79Å; L836-R838 VanDerWaalsContact C-N 3.29Å; L836-R838 PolarHBondContact O-N 2.65Å; R838-Y842 WeakPolarHBondContact O-CB 3.42Å; R838-Y842 PolarHBondContact O-N 2.98Å
839E93.8Very high92.1Very high32 Ų3264.1 Ų64.115%0.1531%0.309CS..Hα-helixtrans-71.4-38.2179.1-55.4-50.312800111.4L795 V798 L836 D837 Y842 L843L795-E839 HydrophobicContact CD1-CB 4.1Å; V798-E839 HydrophobicContact CG2-CG 4.29Å; L836-E839 PolarHBondContact O-N 3.31Å; D837-E839 VanDerWaalsContact C-N 3.29Å; D837-E839 PolarHBondContact O-N 3.24Å; E839-Y842 PolarHBondContact O-N 3.17Å; E839-L843 WeakPolarHBondContact O-CG 3.46Å; E839-L843 PolarHBondContact O-N 2.79Å
840V91.9Very high91.1Very high2 Ų267.3 Ų67.31%0.01233%0.329CS..Hα-helixtrans-64.8-47.1175.5176.40000111.3S770 L795 L836 D837 Y842 L843 L844S770-V840 WeakPolarHBondContact OG-CG2 3.07Å; L795-V840 HydrophobicContact CD1-CG2 3.76Å; L795-V840 HydrophobicContact CD2-CG2 4.37Å; L836-V840 PolarHBondContact O-N 2.66Å; D837-V840 CarbonylContact O-C 3.26Å; D837-V840 PolarHBondContact O-N 3.45Å; V840-Y842 VanDerWaalsContact C-N 3.34Å; V840-Y842 PolarHBondContact O-N 3.04Å; V840-L843 PolarHBondContact O-N 3.05Å; V840-L844 HydrophobicContact CG1-CD1 3.75Å; V840-L844 HydrophobicContact CG1-CG 4.2Å; V840-L844 WeakPolarHBondContact O-CB 3.42Å; V840-L844 WeakPolarHBondContact O-CG 3.33Å; V840-L844 PolarHBondContact O-N 3.4Å
841Q92.8Very high89.6Confident70 Ų7072.5 Ų72.533%0.32735%0.35SS..Hα-helixtrans-64.7-36.6177.2-62.9-57.3-23.900112.2D837 L843 N845D837-Q841 WeakPolarHBondContact O-CG 3.43Å; D837-Q841 PolarHBondContact O-N 3.44Å; D837-Q841 WeakPolarHBondContact OD1-CG 3.41Å; D837-Q841 PolarHBondContact OD1-NE2 2.79Å; D837-Q841 WeakPolarHBondContact OD2-CG 3.47Å; Q841-L843 VanDerWaalsContact C-N 3.34Å; Q841-L843 PolarHBondContact O-N 2.9Å; Q841-N845 VanDerWaalsContact O-CB 3.3Å; Q841-N845 WeakPolarHBondContact O-CB 3.41Å; Q841-N845 VanDerWaalsContact O-CG 3.24Å; Q841-N845 PolarHBondContact O-N 3.31Å; Q841-N845 PolarHBondContact O-ND2 3.25Å
842Y93.4Very high87.8Confident128 Ų12876.2 Ų76.250%0.50237%0.37SS..Hα-helixtrans-56.9-48.7173.1172.6-104.7000111.1E791 R838 E839 V840 K846E791-Y842 HydrophobicContact CG-CE1 4.24Å; E791-Y842 WeakPolarHBondContact OE1-CE1 3.29Å; E791-Y842 PolarHBondContact OE1-OH 2.93Å; R838-Y842 WeakPolarHBondContact O-CB 3.42Å; R838-Y842 PolarHBondContact O-N 2.98Å; E839-Y842 PolarHBondContact O-N 3.17Å; V840-Y842 VanDerWaalsContact C-N 3.34Å; V840-Y842 PolarHBondContact O-N 3.04Å; Y842-K846 WeakPolarHBondContact O-CB 3.27Å; Y842-K846 PolarHBondContact O-N 3.03Å
843L91.7Very high86Confident4 Ų482 Ų822%0.02139%0.39CS..Hα-helixtrans-72.6-41179.5-59.7179.6000112.6F773 F787 E791 L795 E839 V840 Q841 N845 K846 A847F773-L843 HydrophobicContact CE1-CB 3.68Å; F773-L843 HydrophobicContact CE1-CD1 4.02Å; F773-L843 HydrophobicContact CZ-CB 3.79Å; F787-L843 HydrophobicContact CD1-CB 4.12Å; F787-L843 HydrophobicContact CD1-CD2 3.96Å; F787-L843 HydrophobicContact CD1-CG 4.47Å; F787-L843 HydrophobicContact CE1-CB 3.89Å; F787-L843 WeakPolarHBondContact CE1-O 3.33Å; E791-L843 HydrophobicContact CB-CD2 3.81Å; E791-L843 HydrophobicContact CG-CD2 4.11Å; L795-L843 HydrophobicContact CB-CD1 4.24Å; L795-L843 HydrophobicContact CD2-CD1 3.99Å; E839-L843 WeakPolarHBondContact O-CG 3.46Å; E839-L843 PolarHBondContact O-N 2.79Å; V840-L843 PolarHBondContact O-N 3.05Å; Q841-L843 VanDerWaalsContact C-N 3.34Å; Q841-L843 PolarHBondContact O-N 2.9Å; L843-N845 VanDerWaalsContact C-N 3.29Å; L843-N845 PolarHBondContact O-N 3.32Å; L843-K846 WeakPolarHBondContact O-CB 3.49Å; L843-K846 PolarHBondContact O-N 3.22Å; L843-A847 PolarHBondContact O-N 3.26Å
844L89.9Confident83.9Confident44 Ų4485.9 Ų85.923%0.2342%0.419CS..Hα-helixtrans-58.3-40.8174.1-76.3171.9000112F773 V840 A847 K848F773-L844 HydrophobicContact CD2-CD2 3.94Å; F773-L844 HydrophobicContact CE2-CD2 3.54Å; F773-L844 HydrophobicContact CE2-CG 4.09Å; F773-L844 HydrophobicContact CZ-CD2 4.3Å; F773-L844 HydrophobicContact CZ-CG 4.43Å; V840-L844 HydrophobicContact CG1-CD1 3.75Å; V840-L844 HydrophobicContact CG1-CG 4.2Å; V840-L844 WeakPolarHBondContact O-CB 3.42Å; V840-L844 WeakPolarHBondContact O-CG 3.33Å; V840-L844 PolarHBondContact O-N 3.4Å; L844-A847 PolarHBondContact O-N 2.67Å; L844-K848 VanDerWaalsContact O-CG 3.29Å; L844-K848 WeakPolarHBondContact O-CG 3.48Å; L844-K848 PolarHBondContact O-N 2.95Å
845N89.3Confident81.7Confident65 Ų6588.3 Ų88.335%0.34842%0.421SS..Hα-helixtrans-72.3-38.5176.6-68.1-36.6000111.7Q841 L843 A847 K848 F849Q841-N845 VanDerWaalsContact O-CB 3.3Å; Q841-N845 WeakPolarHBondContact O-CB 3.41Å; Q841-N845 VanDerWaalsContact O-CG 3.24Å; Q841-N845 PolarHBondContact O-N 3.31Å; Q841-N845 PolarHBondContact O-ND2 3.25Å; L843-N845 VanDerWaalsContact C-N 3.29Å; L843-N845 PolarHBondContact O-N 3.32Å; N845-A847 VanDerWaalsContact C-N 3.27Å; N845-A847 PolarHBondContact O-N 3.13Å; N845-K848 PolarHBondContact O-N 3.48Å; N845-K848 PolarHBondContact OD1-NZ 3.34Å; N845-F849 HydrophobicContact CB-CE2 4.46Å; N845-F849 WeakPolarHBondContact O-CD2 3.36Å; N845-F849 PolarHBondContact O-N 3.41Å
846K87.8Confident79.3Confident60 Ų6092.5 Ų92.526%0.26145%0.446SS..Hα-helixtrans-57.1-40.5170.5-173176.8-178.3175.50112.1I786 E791 Y842 L843 T850I786-K846 HydrophobicContact CG2-CG 4.49Å; I786-K846 VanDerWaalsContact O-CE 3.31Å; I786-K846 WeakPolarHBondContact O-CE 3.23Å; E791-K846 IonicContact OE1-NZ 2.66Å; E791-K846 PolarHBondContact OE1-NZ 2.62Å; E791-K846 IonicContact OE2-NZ 3.81Å; E791-K846 PolarHBondContact OE2-NZ 3.31Å; Y842-K846 WeakPolarHBondContact O-CB 3.27Å; Y842-K846 PolarHBondContact O-N 3.03Å; L843-K846 WeakPolarHBondContact O-CB 3.49Å; L843-K846 PolarHBondContact O-N 3.22Å; K846-T850 WeakPolarHBondContact O-CB 3.46Å; K846-T850 PolarHBondContact O-N 2.82Å; K846-T850 PolarHBondContact O-OG1 2.98Å
847A85.3Confident77.2Confident32 Ų32101.7 Ų101.726%0.26449%0.486SS..Hα-helixtrans-63-51.5174.900000112.2F787 L843 L844 N845 F849 T850F787-A847 HydrophobicContact CE1-CB 4.16Å; F787-A847 HydrophobicContact CZ-CB 3.93Å; L843-A847 PolarHBondContact O-N 3.26Å; L844-A847 PolarHBondContact O-N 2.67Å; N845-A847 VanDerWaalsContact C-N 3.27Å; N845-A847 PolarHBondContact O-N 3.13Å; A847-F849 PolarHBondContact O-N 3.39Å; A847-F849 VanDerWaalsContact O-N 3.16Å; A847-T850 PolarHBondContact O-N 3.08Å
848K85.1Confident74.6Confident137 Ų137105 Ų10560%0.59650%0.504SS*.Hα-helixtrans-55.8-32.1179.7-70.9166.6-167.3167.50113.8L844 N845L844-K848 VanDerWaalsContact O-CG 3.29Å; L844-K848 WeakPolarHBondContact O-CG 3.48Å; L844-K848 PolarHBondContact O-N 2.95Å; N845-K848 PolarHBondContact O-N 3.48Å; N845-K848 PolarHBondContact OD1-NZ 3.34Å
849F79.4Confident71.9Confident168 Ų168105.2 Ų105.274%0.73751%0.509SS*.Hα-helixtrans-101.70.8-176.6-61.3-59.3000115N845 A847N845-F849 HydrophobicContact CB-CE2 4.46Å; N845-F849 WeakPolarHBondContact O-CD2 3.36Å; N845-F849 PolarHBondContact O-N 3.41Å; A847-F849 PolarHBondContact O-N 3.39Å; A847-F849 VanDerWaalsContact O-N 3.16Å
850T76.9Confident69.3Low66 Ų66111.3 Ų111.341%0.40554%0.542SS..PPolyproline II helixtrans-83126.4177.5-65.90000111.3I786 K846 A847I786-T850 HydrophobicContact CG1-CG2 4.12Å; I786-T850 HydrophobicContact CG2-CG2 4.03Å; I786-T850 WeakPolarHBondContact CG2-OG1 3.24Å; K846-T850 WeakPolarHBondContact O-CB 3.46Å; K846-T850 PolarHBondContact O-N 2.82Å; K846-T850 PolarHBondContact O-OG1 2.98Å; A847-T850 PolarHBondContact O-N 3.08Å
851K63.5Low66.6Low185 Ų185114.2 Ų114.280%0.80457%0.573SS**PPolyproline II helixtrans-85.3138.8178.7-63.4-176.7-179.3-178.80111.1
852P57.9Low63.8Low127 Ų127117.6 Ų117.683%0.82560%0.598SS**PPolyproline II helixtrans-66.2146.4-179.527.4-35000112.3
853R58.8Low60.8Low173 Ų173122.8 Ų122.865%0.65362%0.617SS**PPolyproline II helixtrans-83.5141.1176.8-68.9177.7173.1174.5-2.6111.2M783M783-R853 PolarHBondContact O-NH1 3.46Å
854P52.5Low57.9Low128 Ų128126.7 Ų126.783%0.83165%0.65SS**PPolyproline II helixtrans-73129.9175.429.7-33.5000111.1
855R47.4Very low54.9Low181 Ų181133.1 Ų133.168%0.68368%0.679SS**PPolyproline II helixtrans-84.7143.5179.9-66.6-179.4175.4174.7-2.5112D784D784-R855 IonicContact OD1-NH2 3.42Å; D784-R855 IonicContact OD2-CZ 3.66Å; D784-R855 IonicContact OD2-NE 3.5Å; D784-R855 IonicContact OD2-NH2 3.65Å; D784-R855 PolarHBondContact OD2-NH2 3.4Å
856P45.5Very low53.4Low122 Ų122134.7 Ų134.779%0.79269%0.693SS**PPolyproline II helixtrans-65.5160.1175-19.432.5000113.4
857K50Low51.5Low193 Ų193136.9 Ų136.984%0.83971%0.713SS**  trans-127.8125.9175.8-70.3-175178.2-176.90112.3
858D39.2Very low49.1Very low130 Ų130142 Ų14270%0.69574%0.735SS**  trans-143.2127.3149.9-89.9-51.2000107.9
859K37.3Very low46.6Very low163 Ų163142.7 Ų142.771%0.70975%0.745SS**  6313472.9-61.9-171.4-15295.50112.4
860N38.8Very low44.3Very low160 Ų160138.6 Ų138.686%0.85674%0.742SS**  cis-164.7161.7-13.5-99.5-9.2000104.8
861G36.1Very low41.9Very low63 Ų63140.9 Ų140.965%0.64976%0.761SS**  cis-171.6-166.8-1.900000105
862T34.4Very low40.3Very low141 Ų141136.5 Ų136.587%0.86576%0.759SS**  cis-164172.9-5.3-11.80000104
863R30.6Very low38.8Very low236 Ų236135.7 Ų135.789%0.89176%0.757SS**  cis-158.2174.516.2-140.6-177.4170.4177.3-3.8104.6
864A29.6Very low37.2Very low87 Ų87134.5 Ų134.572%0.71976%0.763SS**  cis-147.1173600000110.4
865E28.2Very low35.9Very low179 Ų179137.3 Ų137.384%0.83677%0.765SS**  trans-154.7172.5-169.6-118.3-162.7-143.100110.2
866P57.7Low34.8Very low98 Ų98132.5 Ų132.564%0.63677%0.772SS**  cis-118.8-113.3-19.434.5-13.5000109.3
867P48.3Very low34.3Very low105 Ų105135.9 Ų135.968%0.68278%0.777SS**  cis-121.8131-4.537-18.1000116.9
868L33.3Very low33Very low141 Ų141135.9 Ų135.974%0.73878%0.778SS**  trans59.6113.7136.6-63.1166.7000123
869N32.9Very low32.5Very low151 Ų151136.3 Ų136.381%0.80779%0.785SS**  69.9146.5130-66.95.6000120.5
870A30.6Very low32.2Very low81 Ų81135.7 Ų135.767%0.66979%0.788SS**  cis-157.9-179.1-0.400000112.4
871S28.3Very low31.9Very low115 Ų115133.3 Ų133.380%0.80478%0.781SS**  trans66.6138.9174.231.20000116.5
872A28.4Very low31.7Very low93 Ų93136.1 Ų136.177%0.76979%0.788SS**  cis79.4137.534.200000113.8
873S26.4Very low31.5Very low110 Ų110134.5 Ų134.577%0.76979%0.789SS**  cis-171.9157.7-9.145.60000112.2
874D25.4Very low31.5Very low148 Ų148126.3 Ų126.379%0.79178%0.778SS**  trans79.6162.3149.6-154.923.6000120.9
875Q25.1Very low31.5Very low186 Ų186131.5 Ų131.587%0.86979%0.787SS**  trans74.6128.4178.1-56.4-164.92.300118.5
876G24.7Very low31.4Very low81 Ų81128 Ų12884%0.83578%0.778SS**  trans169.347.9-178.400000115.4K878G876-K878 PolarHBondContact O-N 3.22Å
877E34.3Very low30.1Very low192 Ų192130.4 Ų130.490%0.89778%0.78SS**  trans-67.4123.4178.3-131.5-166.7163.500112.4
878K24.4Very low29.1Very low194 Ų194132.3 Ų132.384%0.84379%0.785SS**  trans171.1135.3140.7-96.9155.4-172.4172.30112.1G876G876-K878 PolarHBondContact O-N 3.22Å
879V27.5Very low28.9Very low139 Ų139130.6 Ų130.684%0.84279%0.791SS**  trans-118.6128.6159.51770000108.3
880I31.8Very low28.7Very low150 Ų150132.3 Ų132.377%0.76979%0.794SS**  trans-106.1129.3168.1-60.7172.2000106.2
881P32.5Very low28.7Very low109 Ų109133.3 Ų133.371%0.70879%0.794SS**PPolyproline II helixtrans-82.2148-175.732.7-35.3000112.6
882P31.7Very low28.6Very low123 Ų123136 Ų13680%0.79980%0.797SS**PPolyproline II helixtrans-87.3149.4160.734.8-31.4000111.5
883A30.4Very low28.6Very low107 Ų107137 Ų13788%0.88480%0.799SS**PPolyproline II helixtrans-84.5159.7166.400000110.8
884G30.1Very low28.6Very low64 Ų64140.7 Ų140.766%0.6680%0.804SS**  cis158.4-179.5-3.700000111.3
885Q29.6Very low29Very low196 Ų196139.5 Ų139.592%0.91680%0.804SS**  trans67.3140.1177.1-61.7-179.7-1800115.5
886T26.5Very low29.1Very low104 Ų104138.1 Ų138.164%0.63880%0.798SS**  cis-120.4-172.2-2.362.80000110.6
887E29.1Very low29.2Very low149 Ų149141.5 Ų141.570%0.69679%0.79SS**  cis-153.31747-148.786.8-108.500109.6
888D27.9Very low29Very low145 Ų145138 Ų13878%0.77578%0.781SS**  trans31.7116.1156.6-67.3-13.6000124.1
889A28.8Very low29.1Very low106 Ų106136.5 Ų136.588%0.87678%0.777SS**  trans75.3121.7137.100000122.5
890E29.5Very low29.1Very low186 Ų186136.2 Ų136.287%0.86978%0.776SS**  trans-69.1169.7167.4-67.9-173.3160.100113
891P31.1Very low28.8Very low102 Ų102132.3 Ų132.366%0.66277%0.773SS**  cis-146.2167.823.643.4-23.8000120.3
892I26.3Very low28.6Very low171 Ų171132.5 Ų132.588%0.87778%0.777SS**  trans64.2136.7151.3-67.3157.8000119
893S26.8Very low28.5Very low114 Ų114135.7 Ų135.780%0.79778%0.781SS**  trans-135159.3169.964.60000112.7
894E27Very low28.6Very low188 Ų188136.7 Ų136.788%0.87978%0.779SS**  trans-81.8168.2-174.5-56.4166.6123.400114.3
895P34.2Very low28.5Very low123 Ų123137 Ų13780%0.79978%0.782SS**  trans-115.8142.7169.338.3-27.9000115.3
896E27.3Very low28.5Very low158 Ų158135.5 Ų135.574%0.73878%0.78SS**  trans-146.2151.8160.9-75.1-148.1159.700108.3
897K26.9Very low28.6Very low151 Ų151137.3 Ų137.366%0.65779%0.791SS**  cis-167.2149.6-10.2-113.8180-172.11450108.9
898V29.6Very low28.7Very low119 Ų119139.1 Ų139.172%0.72180%0.8SS**  trans47.3134.2130.9173.70000118.6
899E27Very low29.1Very low163 Ų163137.3 Ų137.376%0.76280%0.796SS**  cis-163.3147.115.6-141.4165.8-126.400109.8
900T26Very low29Very low132 Ų132140.6 Ų140.681%0.8180%0.798SS**  157.9160.798.640.50000108.4
901G26.5Very low29Very low69 Ų69140.5 Ų140.571%0.71180%0.797SS**  trans140.370.2159.800000120
902S27.6Very low29Very low112 Ų112144.1 Ų144.178%0.78381%0.81SS**  trans28.5132144.357.80000124.1
903E29.5Very low29.1Very low190 Ų190140 Ų14089%0.88881%0.81SS**  trans83.3130.4153-67.5-174.1177.200120.4
904P32.9Very low29Very low129 Ų129138.2 Ų138.284%0.83881%0.81SS**  trans-98.4157.8179.739.2-34.7000113.8
905G27.9Very low29.8Very low71 Ų71135.6 Ų135.673%0.73281%0.809SS**  trans-122.3158.4166.600000111.8
906D30.6Very low29.5Very low163 Ų163133.7 Ų133.787%0.87281%0.812SS**  trans-70.9144.2-169.6-48.6-87.2000115.1
907T28.3Very low29.6Very low143 Ų143131.2 Ų131.288%0.87782%0.818SS**  trans-149.1127.2147.937.20000110.5
908E31.2Very low29.9Very low187 Ų187133.4 Ų133.487%0.87483%0.831SS**  trans-92.8-176.7169.9-124.4-163.3-173.500110.7
909P35.3Very low30.8Very low107 Ų107133.1 Ų133.170%0.69583%0.831SS**  -106.8170.9-125.239.8-30000115.8
910L28.1Very low30.9Very low174 Ų174133.1 Ų133.191%0.91183%0.831SS**  trans-82.6120.9173.2-73.6161.5000111.7
911E29.1Very low31.1Very low185 Ų185134.8 Ų134.886%0.86483%0.83SS**  trans-87.3141.2162.7-70.9-164.9139.800111.6
912L30Very low31.3Very low178 Ų178140.6 Ų140.693%0.93284%0.836SS**  trans-147.4133.1166.8-88176.8000111.3
913G28.7Very low31.3Very low84 Ų84143.6 Ų143.687%0.86684%0.837SS**  trans108.393.3153.600000117.3
914G26.2Very low31.4Very low77 Ų77142.8 Ų142.879%0.79483%0.833SS**  trans-148.9121163.600000111
915P42.3Very low31.1Very low133 Ų133142.1 Ų142.186%0.86483%0.832SS**  trans-108.6130-176.535.9-29.1000114.9
916G28.1Very low31.2Very low83 Ų83145.4 Ų145.486%0.85684%0.838SS**  trans81.9107.1133.900000120.5
917A29.8Very low31.2Very low106 Ų106140.9 Ų140.988%0.87683%0.829SS**  trans-150.9150.7143.100000109.3
918E33.9Very low31.3Very low196 Ų196142.3 Ų142.392%0.91683%0.826SS**  trans-93.5163.7-169.8-79.6-173133.900114.7
919P47Very low31.3Very low113 Ų113142.2 Ų142.273%0.73482%0.823SS**  trans-105.8162.2-167.439.8-33.9000114.5
920E30.8Very low31Very low164 Ų164148.6 Ų148.677%0.76683%0.833SS**  trans-145.7133.2156.5-90.9-139.311300115.7
921Q29.4Very low32.1Very low167 Ų167145.3 Ų145.378%0.7882%0.822SS**  trans67.1160.3147.6-57.6-165.432.600122.1
922K30.1Very low32.1Very low191 Ų191143.4 Ų143.483%0.8382%0.817SS**  trans-120155-157.4-56160.4178.9167.40111.6
923E29.2Very low32Very low174 Ų174143 Ų14381%0.81381%0.808SS**  159.8109.7119.5-87.6-179.6-179.300109.5
924Q29.9Very low32Very low174 Ų174144.3 Ų144.381%0.81380%0.795SS**  85.8110.380.3-88.1-1522.500115.8
925S28Very low32.2Very low114 Ų114146.7 Ų146.780%0.79779%0.79SS**  trans70.4149.715789.80000116.2
926T30.2Very low31.7Very low141 Ų141149 Ų14987%0.86579%0.789SS**  cis-135.8-179.3-9.3580000106.3
927G29.4Very low31.9Very low67 Ų67156 Ų15669%0.69181%0.806SS**  cis161110.42.500000111.4
928Q30.8Very low32Very low174 Ų174158.6 Ų158.681%0.81380%0.802SS**  trans73.7149.2164.5-65.1-164.81.800122.4
929K31.1Very low31.9Very low185 Ų185156.6 Ų156.680%0.80480%0.796SS**  trans78.791.8157.1-72.7166.8-171178.50120.8
930R29.1Very low31.1Very low240 Ų240159 Ų15991%0.90680%0.8SS**  trans-52.4167135.3-73.9-175.5180-179.20.5111.1
931P50.6Low31.1Very low106 Ų106158.7 Ų158.769%0.68880%0.802SS**  cis-148.517027.839.6-17.5000120.8
932L28.8Very low31.2Very low145 Ų145158.2 Ų158.276%0.75980%0.803SS**  trans74.7117.5147.4-73.2157.8000122.4
933K28.8Very low31.3Very low170 Ų170156 Ų15674%0.73980%0.801SS**  81.8135.1128.2-84.5-167.4168.5-161.10123.1
934N29.5Very low31.4Very low111 Ų111154.7 Ų154.759%0.59480%0.8SS**  trans67.1141.8141.8-70.853.9000117.4
935D29.9Very low31.6Very low127 Ų127153.2 Ų153.268%0.67980%0.799SS**  cis-149.6-179.2-6.6-92.2-33.1000109.1
936E31.3Very low31.8Very low181 Ų181156.5 Ų156.585%0.84680%0.799SS**  trans72.2141.3173.4-57.5173.1-173.900114.9
937L32.7Very low32Very low231 Ų231157.9 Ų157.9100%1.20979%0.793SS**  cis-144.806.6-138.6167.3000110.3

Retrieved 937 of 937 residues in 1639 ms (Link to these results)