A0A087X104_HUMAN Loading...

EPS8 signaling adaptor L3

AlphaFold DB , UniProt , Accession A0A087X104, Species HUMAN (Homo sapiens, Human), Gene EPS8L3, Length 39 aa.

>A0A087X104_HUMAN|A0A087X104|EPS8L3
MSRPSSRAIYLHRKEYSQNLTSEPTLLQHRVEHACGPPL
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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M60.6Low90.7Very high244 Ų244124.3 Ų124.3100%1.20264%0.637SS**  0126.50-84.9159.9137.800108.7
2S86.4Confident91Very high117 Ų117124.7 Ų124.782%0.81863%0.633SS**PPolyproline II helixtrans-71.6147.917437.30000110.8
3R90.6Very high90.9Very high234 Ų234128.7 Ų128.788%0.88364%0.636SS**PPolyproline II helixtrans-67.9128.4177.3-157.416794.7100.2-4109.3
4P90.7Very high91.1Very high77 Ų77126.9 Ų126.950%0.562%0.623SS.*PPolyproline II helixtrans-64.1142.1179.324.8-32.3000110.7A8 I9P4-A8 HydrophobicContact CB-CB 4.25Å; P4-I9 HydrophobicContact CB-CG1 4.23Å; P4-I9 HydrophobicContact CG-CD1 4.48Å; P4-I9 HydrophobicContact CG-CG1 4.28Å
5S96.2Very high91Very high70 Ų70125.5 Ų125.549%0.4961%0.614SS.*PPolyproline II helixtrans-71.7158.6174.568.90000111R7 A8 I9S5-R7 PolarHBondContact O-N 3.04Å; S5-A8 WeakPolarHBondContact O-CB 3.39Å; S5-A8 PolarHBondContact O-N 3.02Å; S5-A8 PolarHBondContact OG-N 3.25Å; S5-A8 VanDerWaalsContact OG-N 3.17Å; S5-I9 WeakPolarHBondContact O-CG1 3.47Å; S5-I9 PolarHBondContact O-N 3.37Å
6S96Very high90.7Very high105 Ų105124.9 Ų124.973%0.73460%0.604SS**Hα-helixtrans-55.9-34174.5-52.30000112.3I9 Y10S6-I9 PolarHBondContact O-N 3.14Å; S6-Y10 WeakPolarHBondContact O-CB 3.49Å; S6-Y10 PolarHBondContact O-N 3.4Å
7R95Very high90.3Very high184 Ų184121.5 Ų121.569%0.69460%0.596SS**Hα-helixtrans-65.8-43.2174.4-175.8175.5-178.4-97.30.7111.9S5 I9 Y10 L11S5-R7 PolarHBondContact O-N 3.04Å; R7-I9 VanDerWaalsContact C-N 3.34Å; R7-Y10 PolarHBondContact O-N 3.39Å; R7-L11 HydrophobicContact CG-CD1 4.17Å; R7-L11 WeakPolarHBondContact O-CG 3.43Å; R7-L11 PolarHBondContact O-N 3.49Å
8A94.8Very high89.9Confident44 Ų44120.6 Ų120.636%0.36459%0.59SS.*Hα-helixtrans-62.9-42.3176.900000111.3P4 S5 Y10 L11 H12P4-A8 HydrophobicContact CB-CB 4.25Å; S5-A8 WeakPolarHBondContact O-CB 3.39Å; S5-A8 PolarHBondContact O-N 3.02Å; S5-A8 PolarHBondContact OG-N 3.25Å; S5-A8 VanDerWaalsContact OG-N 3.17Å; A8-Y10 PolarHBondContact O-N 3.29Å; A8-L11 PolarHBondContact O-N 3.26Å; A8-H12 WeakPolarHBondContact O-CB 3.38Å; A8-H12 PolarHBondContact O-N 2.78Å
9I96.1Very high89.4Confident81 Ų81119.8 Ų119.842%0.41559%0.589SS.*Hα-helixtrans-61.5-44.6175.2-62.7167.6000110.7P4 S5 S6 R7 R13P4-I9 HydrophobicContact CB-CG1 4.23Å; P4-I9 HydrophobicContact CG-CD1 4.48Å; P4-I9 HydrophobicContact CG-CG1 4.28Å; S5-I9 WeakPolarHBondContact O-CG1 3.47Å; S5-I9 PolarHBondContact O-N 3.37Å; S6-I9 PolarHBondContact O-N 3.14Å; R7-I9 VanDerWaalsContact C-N 3.34Å; I9-R13 VanDerWaalsContact O-CG 3.28Å; I9-R13 WeakPolarHBondContact O-CG 3.48Å; I9-R13 PolarHBondContact O-N 3.22Å
10Y95.8Very high88.5Confident154 Ų154116.3 Ų116.360%0.60457%0.573SS**Hα-helixtrans-62.2-48.4179174.3-96.3000112.6S6 R7 A8 R13 K14S6-Y10 WeakPolarHBondContact O-CB 3.49Å; S6-Y10 PolarHBondContact O-N 3.4Å; R7-Y10 PolarHBondContact O-N 3.39Å; A8-Y10 PolarHBondContact O-N 3.29Å; Y10-R13 PolarHBondContact O-N 3.32Å; Y10-K14 HydrophobicContact CE1-CD 4.44Å; Y10-K14 WeakPolarHBondContact O-CB 3.22Å; Y10-K14 PolarHBondContact O-N 2.92Å
11L96.1Very high87.8Confident57 Ų57116 Ų11630%0.29858%0.578SS.*Hα-helixtrans-62-46.1-180-70.9172.7000111.4R7 A8 R13 K14 E15R7-L11 HydrophobicContact CG-CD1 4.17Å; R7-L11 WeakPolarHBondContact O-CG 3.43Å; R7-L11 PolarHBondContact O-N 3.49Å; A8-L11 PolarHBondContact O-N 3.26Å; L11-R13 VanDerWaalsContact C-N 3.32Å; L11-R13 PolarHBondContact O-N 3.25Å; L11-K14 WeakPolarHBondContact O-CB 3.39Å; L11-K14 PolarHBondContact O-N 3.4Å; L11-K14 VanDerWaalsContact O-N 3.14Å; L11-E15 WeakPolarHBondContact O-CG 3.49Å; L11-E15 PolarHBondContact O-N 3.24Å
12H93.5Very high88.4Confident129 Ų129108.1 Ų108.160%0.59755%0.547SS*.Hα-helixtrans-58-44.2176.5179.8-89.8000112A8 Y16A8-H12 WeakPolarHBondContact O-CB 3.38Å; A8-H12 PolarHBondContact O-N 2.78Å; H12-Y16 VanDerWaalsContact O-CB 3.29Å; H12-Y16 WeakPolarHBondContact O-CB 3.35Å; H12-Y16 PolarHBondContact O-N 3.35Å
13R90.7Very high87.4Confident177 Ų177107.6 Ų107.667%0.66853%0.531SS*.Hα-helixtrans-63.6-42.6176.5-73.1178.272.1-179.33.6112I9 Y10 L11 Y16 S17I9-R13 VanDerWaalsContact O-CG 3.28Å; I9-R13 WeakPolarHBondContact O-CG 3.48Å; I9-R13 PolarHBondContact O-N 3.22Å; Y10-R13 PolarHBondContact O-N 3.32Å; L11-R13 VanDerWaalsContact C-N 3.32Å; L11-R13 PolarHBondContact O-N 3.25Å; R13-Y16 PolarHBondContact O-N 3.46Å; R13-S17 WeakPolarHBondContact O-CB 3.45Å; R13-S17 PolarHBondContact O-N 3.48Å; R13-S17 PolarHBondContact O-OG 3.48Å
14K92.8Very high86Confident103 Ų103100 Ų10045%0.44851%0.512SS..Hα-helixtrans-60.6-49.9177.9-177.6-176.2173.8-174.30111Y10 L11 S17 Q18Y10-K14 HydrophobicContact CE1-CD 4.44Å; Y10-K14 WeakPolarHBondContact O-CB 3.22Å; Y10-K14 PolarHBondContact O-N 2.92Å; L11-K14 WeakPolarHBondContact O-CB 3.39Å; L11-K14 PolarHBondContact O-N 3.4Å; L11-K14 VanDerWaalsContact O-N 3.14Å; K14-S17 PolarHBondContact O-N 3.37Å; K14-Q18 WeakPolarHBondContact O-CG 3.39Å; K14-Q18 PolarHBondContact O-N 3.29Å
15E89.8Confident84.5Confident106 Ų106100.8 Ų100.850%0.49552%0.516SS..Hα-helixtrans-63-44.7178.8-72.1169.7-152.600111.5L11 S17 Q18 N19L11-E15 WeakPolarHBondContact O-CG 3.49Å; L11-E15 PolarHBondContact O-N 3.24Å; E15-S17 PolarHBondContact O-N 2.93Å; E15-Q18 PolarHBondContact O-N 2.87Å; E15-N19 WeakPolarHBondContact O-CB 3.29Å; E15-N19 PolarHBondContact O-N 3Å; E15-N19 PolarHBondContact O-ND2 3.29Å
16Y86.3Confident82.7Confident117 Ų117102.2 Ų102.246%0.45952%0.517SS..Hα-helixtrans-58.1-49.8175.6-175.3-104.5000111.2H12 R13 Q18 N19 L20H12-Y16 VanDerWaalsContact O-CB 3.29Å; H12-Y16 WeakPolarHBondContact O-CB 3.35Å; H12-Y16 PolarHBondContact O-N 3.35Å; R13-Y16 PolarHBondContact O-N 3.46Å; Y16-Q18 VanDerWaalsContact C-N 3.31Å; Y16-Q18 PolarHBondContact O-N 3.2Å; Y16-N19 PolarHBondContact O-N 3.18Å; Y16-L20 HydrophobicContact CD1-CD1 3.47Å; Y16-L20 VanDerWaalsContact CD1-CD1 3.47Å; Y16-L20 HydrophobicContact CD1-CD2 4.48Å; Y16-L20 HydrophobicContact CD1-CG 3.94Å; Y16-L20 HydrophobicContact CE1-CD1 3.28Å; Y16-L20 HydrophobicContact CE1-CD2 3.82Å; Y16-L20 HydrophobicContact CE1-CG 3.74Å; Y16-L20 HydrophobicContact CE2-CD2 4.32Å; Y16-L20 HydrophobicContact CG-CD1 4.4Å; Y16-L20 HydrophobicContact CG-CG 4.45Å; Y16-L20 VanDerWaalsContact O-CG 3.22Å; Y16-L20 WeakPolarHBondContact O-CG 3.47Å; Y16-L20 PolarHBondContact O-N 3.38Å
17S84.2Confident80.8Confident67 Ų6799.2 Ų99.247%0.46949%0.493SS..Hα-helixtrans-59-38.9176.8-74.10000113.3R13 K14 E15 L20 T21R13-S17 WeakPolarHBondContact O-CB 3.45Å; R13-S17 PolarHBondContact O-N 3.48Å; R13-S17 PolarHBondContact O-OG 3.48Å; K14-S17 PolarHBondContact O-N 3.37Å; E15-S17 PolarHBondContact O-N 2.93Å; S17-L20 PolarHBondContact O-N 2.91Å; S17-T21 PolarHBondContact O-N 2.9Å; S17-T21 PolarHBondContact O-OG1 3.48Å
18Q83.6Confident79Confident104 Ų10496.3 Ų96.349%0.48649%0.487SS..Hα-helixtrans-67.6-42.7175.9-72-177.5-62.900112.1K14 E15 Y16 L20 T21 S22K14-Q18 WeakPolarHBondContact O-CG 3.39Å; K14-Q18 PolarHBondContact O-N 3.29Å; E15-Q18 PolarHBondContact O-N 2.87Å; Y16-Q18 VanDerWaalsContact C-N 3.31Å; Y16-Q18 PolarHBondContact O-N 3.2Å; Q18-L20 VanDerWaalsContact C-N 3.32Å; Q18-L20 PolarHBondContact O-N 2.92Å; Q18-T21 PolarHBondContact O-N 3.09Å; Q18-T21 PolarHBondContact O-OG1 2.94Å; Q18-S22 PolarHBondContact O-N 3.02Å; Q18-S22 PolarHBondContact O-OG 3.14Å; Q18-S22 VanDerWaalsContact O-OG 3.04Å
19N78.9Confident77.1Confident106 Ų10699.6 Ų99.657%0.56749%0.494SS*.Hα-helixtrans-64.6-37.4176.7-72.9-48.8000112.1E15 Y16 T21 S22 E23E15-N19 WeakPolarHBondContact O-CB 3.29Å; E15-N19 PolarHBondContact O-N 3Å; E15-N19 PolarHBondContact O-ND2 3.29Å; Y16-N19 PolarHBondContact O-N 3.18Å; N19-T21 VanDerWaalsContact C-N 3.28Å; N19-T21 PolarHBondContact O-N 3.1Å; N19-S22 PolarHBondContact O-N 3.37Å; N19-E23 PolarHBondContact O-N 2.92Å; N19-E23 VanDerWaalsContact O-N 3.14Å
20L72.8Confident75.2Confident50 Ų50102.4 Ų102.426%0.26250%0.5SS..Hα-helixtrans-59.9-38.2174.7-71.4171.4000112Y16 S17 Q18 L27Y16-L20 HydrophobicContact CD1-CD1 3.47Å; Y16-L20 VanDerWaalsContact CD1-CD1 3.47Å; Y16-L20 HydrophobicContact CD1-CD2 4.48Å; Y16-L20 HydrophobicContact CD1-CG 3.94Å; Y16-L20 HydrophobicContact CE1-CD1 3.28Å; Y16-L20 HydrophobicContact CE1-CD2 3.82Å; Y16-L20 HydrophobicContact CE1-CG 3.74Å; Y16-L20 HydrophobicContact CE2-CD2 4.32Å; Y16-L20 HydrophobicContact CG-CD1 4.4Å; Y16-L20 HydrophobicContact CG-CG 4.45Å; Y16-L20 VanDerWaalsContact O-CG 3.22Å; Y16-L20 WeakPolarHBondContact O-CG 3.47Å; Y16-L20 PolarHBondContact O-N 3.38Å; S17-L20 PolarHBondContact O-N 2.91Å; Q18-L20 VanDerWaalsContact C-N 3.32Å; Q18-L20 PolarHBondContact O-N 2.92Å; L20-L27 HydrophobicContact CB-CD1 4.1Å; L20-L27 HydrophobicContact CD2-CD1 3.16Å; L20-L27 HydrophobicContact CD2-CD2 3.3Å; L20-L27 HydrophobicContact CD2-CG 3.7Å; L20-L27 HydrophobicContact CG-CD1 4.21Å
21T73.3Confident73.4Confident110 Ų11099.7 Ų99.768%0.67550%0.499SS*.Hα-helixtrans-80.4-30-179.550.10000113.5S17 Q18 N19S17-T21 PolarHBondContact O-N 2.9Å; S17-T21 PolarHBondContact O-OG1 3.48Å; Q18-T21 PolarHBondContact O-N 3.09Å; Q18-T21 PolarHBondContact O-OG1 2.94Å; N19-T21 VanDerWaalsContact C-N 3.28Å; N19-T21 PolarHBondContact O-N 3.1Å
22S74.1Confident71.6Confident79 Ų79103.2 Ų103.255%0.55251%0.514SS*.Hα-helixtrans-79.4-34.7-178.3-59.90000112.8Q18 N19 P24Q18-S22 PolarHBondContact O-N 3.02Å; Q18-S22 PolarHBondContact O-OG 3.14Å; Q18-S22 VanDerWaalsContact O-OG 3.04Å; N19-S22 PolarHBondContact O-N 3.37Å; S22-P24 VanDerWaalsContact C-CD 3.45Å; S22-P24 WeakPolarHBondContact O-CD 3.43Å
23E65.3Low69.9Low106 Ų106104.2 Ų104.250%0.49552%0.519SS..  trans-126.167.7-177.7-67.8-64.6138.700111.2N19 T25 L26N19-E23 PolarHBondContact O-N 2.92Å; N19-E23 VanDerWaalsContact O-N 3.14Å; E23-T25 PolarHBondContact O-N 3.05Å; E23-L26 HydrophobicContact CB-CB 4.27Å; E23-L26 HydrophobicContact CB-CD1 4.23Å; E23-L26 PolarHBondContact O-N 3.36Å
24P59.8Low68.4Low73 Ų73100 Ų10047%0.47452%0.522SS..THydrogen-bonded Turntrans-64-27-175.425.4-34000113.2S22 L27S22-P24 VanDerWaalsContact C-CD 3.45Å; S22-P24 WeakPolarHBondContact O-CD 3.43Å; P24-L27 PolarHBondContact O-N 3.48Å
25T60.3Low66.5Low95 Ų9599.8 Ų99.858%0.58353%0.532SS*.Hα-helixtrans-71.8-30.2179.728.60000113.4E23 L27 Q28 H29E23-T25 PolarHBondContact O-N 3.05Å; T25-L27 PolarHBondContact O-N 2.97Å; T25-Q28 PolarHBondContact O-N 3.28Å; T25-H29 PolarHBondContact O-N 2.91Å
26L57.6Low65.3Low99 Ų9997.4 Ų97.452%0.51854%0.536SS..Hα-helixtrans-71.3-17.1178.1-113156.6000113.1E23 R30E23-L26 HydrophobicContact CB-CB 4.27Å; E23-L26 HydrophobicContact CB-CD1 4.23Å; E23-L26 PolarHBondContact O-N 3.36Å; L26-R30 WeakPolarHBondContact O-CG 3.28Å; L26-R30 PolarHBondContact O-NE 3.04Å; L26-R30 VanDerWaalsContact O-NE 3.09Å
27L56.7Low64.1Low43 Ų4397.3 Ų97.323%0.22555%0.55CS..Hα-helixtrans-85.1-41173.4-70.3159.7000112.5L20 P24 T25 H29 R30 V31L20-L27 HydrophobicContact CB-CD1 4.1Å; L20-L27 HydrophobicContact CD2-CD1 3.16Å; L20-L27 HydrophobicContact CD2-CD2 3.3Å; L20-L27 HydrophobicContact CD2-CG 3.7Å; L20-L27 HydrophobicContact CG-CD1 4.21Å; P24-L27 PolarHBondContact O-N 3.48Å; T25-L27 PolarHBondContact O-N 2.97Å; L27-H29 VanDerWaalsContact C-N 3.26Å; L27-H29 PolarHBondContact O-N 3.22Å; L27-R30 VanDerWaalsContact CD2-NH2 3.31Å; L27-R30 PolarHBondContact O-N 3.1Å; L27-R30 VanDerWaalsContact O-N 3.1Å; L27-V31 WeakPolarHBondContact O-CG2 3.37Å; L27-V31 PolarHBondContact O-N 3.17Å
28Q56.6Low62.9Low123 Ų123100.4 Ų100.458%0.57557%0.568SS**Hα-helixtrans-56.2-47.1177.1-67.4-172.55.400110.2T25 R30 V31 E32T25-Q28 PolarHBondContact O-N 3.28Å; Q28-R30 VanDerWaalsContact C-N 3.31Å; Q28-R30 PolarHBondContact O-N 3.02Å; Q28-V31 PolarHBondContact O-N 2.99Å; Q28-E32 WeakPolarHBondContact O-CG 3.46Å; Q28-E32 PolarHBondContact O-N 3.29Å
29H55.3Low61.7Low112 Ų112107.2 Ų107.252%0.51961%0.607SS.*Hα-helixtrans-62.1-35178.3-149.5-169.1000112.8T25 L27 H33T25-H29 PolarHBondContact O-N 2.91Å; L27-H29 VanDerWaalsContact C-N 3.26Å; L27-H29 PolarHBondContact O-N 3.22Å; H29-H33 AromaticContact CD2-NE2 3.91Å; H29-H33 AromaticContact NE2-NE2 3.87Å; H29-H33 PolarHBondContact O-CD2 2.95Å; H29-H33 PolarHBondContact O-N 3.29Å
30R56.7Low60.8Low141 Ų141107.3 Ų107.353%0.53261%0.609SS.*Hα-helixtrans-75.8-32.8176.6-76.3-175.2-71176-1.4113.5L26 L27 Q28 A34L26-R30 WeakPolarHBondContact O-CG 3.28Å; L26-R30 PolarHBondContact O-NE 3.04Å; L26-R30 VanDerWaalsContact O-NE 3.09Å; L27-R30 VanDerWaalsContact CD2-NH2 3.31Å; L27-R30 PolarHBondContact O-N 3.1Å; L27-R30 VanDerWaalsContact O-N 3.1Å; Q28-R30 VanDerWaalsContact C-N 3.31Å; Q28-R30 PolarHBondContact O-N 3.02Å; R30-A34 WeakPolarHBondContact O-CB 3.43Å; R30-A34 PolarHBondContact O-N 3.18Å
31V56.8Low60.2Low97 Ų97110.3 Ų110.359%0.58863%0.627SS**Hα-helixtrans-70.7-40.8175.5173.50000110.4L27 Q28 H33 A34 C35L27-V31 WeakPolarHBondContact O-CG2 3.37Å; L27-V31 PolarHBondContact O-N 3.17Å; Q28-V31 PolarHBondContact O-N 2.99Å; V31-H33 PolarHBondContact O-N 3.49Å; V31-A34 PolarHBondContact O-N 3.17Å; V31-C35 PolarHBondContact O-N 3.46Å; V31-C35 VanDerWaalsContact O-N 3.1Å
32E58Low59.4Low130 Ų130110.3 Ų110.361%0.60762%0.624SS**Hα-helixtrans-59.3-32.4174.9-75.1174.1-172.300112.7Q28 C35Q28-E32 WeakPolarHBondContact O-CG 3.46Å; Q28-E32 PolarHBondContact O-N 3.29Å; E32-C35 VanDerWaalsContact O-O 3.13Å
33H58Low58.6Low151 Ų151112.1 Ų112.170%0.69963%0.628SS**Hα-helixtrans-84.3-16.1174.5-73.7-61.7000114.5H29 V31H29-H33 AromaticContact CD2-NE2 3.91Å; H29-H33 AromaticContact NE2-NE2 3.87Å; H29-H33 PolarHBondContact O-CD2 2.95Å; H29-H33 PolarHBondContact O-N 3.29Å; V31-H33 PolarHBondContact O-N 3.49Å
34A59.7Low58.2Low89 Ų89112.5 Ų112.574%0.73664%0.637SS**Hα-helixtrans-92.7-21.2-17900000113.4R30 V31R30-A34 WeakPolarHBondContact O-CB 3.43Å; R30-A34 PolarHBondContact O-N 3.18Å; V31-A34 PolarHBondContact O-N 3.17Å
35C53.1Low58Low98 Ų98115.1 Ų115.166%0.66265%0.648SS**SBendtrans-102.8107.1168.4-135.60000107V31 E32V31-C35 PolarHBondContact O-N 3.46Å; V31-C35 VanDerWaalsContact O-N 3.1Å; E32-C35 VanDerWaalsContact O-O 3.13Å
36G63.5Low57.9Low56 Ų56116.6 Ų116.658%0.57765%0.652SS**PPolyproline II helixtrans-53159.4177.200000112.3
37P61.4Low57.9Low115 Ų115117.9 Ų117.975%0.74766%0.662SS**PPolyproline II helixtrans-54.9139.1-177.223.6-32.6000110.3L39P37-L39 PolarHBondContact O-N 3Å
38P60Low58Low132 Ų132124.2 Ų124.286%0.85770%0.699SS**PPolyproline II helixtrans-62121.3175.925.3-31000108.9
39L57.1Low58.1Low246 Ų246124.3 Ų124.3100%1.28871%0.71SS**  trans-85.10162.9-70.5175.4000109.5P37P37-L39 PolarHBondContact O-N 3Å

Retrieved 39 of 39 residues in 31.3 ms (Link to these results)