A0A087X147_HUMAN Loading...

BTB domain containing 2

AlphaFold DB , UniProt , Accession A0A087X147, Species HUMAN (Homo sapiens, Human), Gene BTBD2, Length 35 aa.

						>A0A087X147_HUMAN|A0A087X147|BTBD2
MFNGGMATTSTEIELPDVEPAAFLALLKFLYSDEV
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	58.7	Low	65.4	Low	237 Å²	237	131.5 Å²	131.5	100%	1.167	80%	0.798	S	S	*	*				0	-22.5	0	-158.4	-180	-127.1	0	112.8
2	F	54.7	Low	67	Low	205 Å²	205	134 Å²	134	90%	0.899	79%	0.794	S	S	*	*			trans	-115.8	56.7	-177.9	-106.1	-86.9	0	0	112.7
3	N	52.1	Low	68.5	Low	140 Å²	140	134 Å²	134	75%	0.749	79%	0.786	S	S	*	*			trans	-140.4	43.9	172.3	-141.2	15.8	0	0	112.2	G5	N3-G5 PolarHBondContact O-N 3.44Å
4	G	56.1	Low	69.8	Low	65 Å²	65	138.4 Å²	138.4	67%	0.67	80%	0.795	S	S	*	*	S	Bend	trans	-88.9	81.3	175.6	0	0	0	0	110.7	M6	G4-M6 PolarHBondContact O-N 3.31Å
5	G	58.6	Low	70.7	Confident	85 Å²	85	134.9 Å²	134.9	88%	0.876	77%	0.772	S	S	*	*	S	Bend	trans	55.8	-5.7	158.5	0	0	0	0	120.1	N3	N3-G5 PolarHBondContact O-N 3.44Å
6	M	61.1	Low	71.5	Confident	172 Å²	172	133 Å²	133	85%	0.847	77%	0.766	S	S	*	*			trans	-107.4	10.8	-177.4	-67.2	174.9	158.6	0	111.6	G4 T8	G4-M6 PolarHBondContact O-N 3.31Å; M6-T8 VanDerWaalsContact C-N 3.31Å; M6-T8 PolarHBondContact O-N 2.9Å
7	A	63.4	Low	72.4	Confident	78 Å²	78	135.8 Å²	135.8	65%	0.645	78%	0.778	S	S	*	*			trans	-68.7	93.7	172.9	0	0	0	0	108.2
8	T	70.3	Confident	73.2	Confident	99 Å²	99	132.2 Å²	132.2	61%	0.607	76%	0.758	S	S	*	*			trans	-80.5	149.2	170	59.6	0	0	0	108.6	M6 S10	M6-T8 VanDerWaalsContact C-N 3.31Å; M6-T8 PolarHBondContact O-N 2.9Å; T8-S10 PolarHBondContact O-N 2.83Å
9	T	78.6	Confident	74.2	Confident	146 Å²	146	132.5 Å²	132.5	90%	0.896	75%	0.752	S	S	*	*			trans	-82.3	12.9	172.3	58.3	0	0	0	112
10	S	81.7	Confident	74.9	Confident	78 Å²	78	131.2 Å²	131.2	55%	0.545	75%	0.749	S	S	.	*			trans	-70	133.9	-178.8	-60.5	0	0	0	109.6	T8 E12	T8-S10 PolarHBondContact O-N 2.83Å; S10-E12 PolarHBondContact O-N 3.27Å
11	T	84	Confident	75.7	Confident	142 Å²	142	128 Å²	128	87%	0.871	74%	0.739	S	S	*	*	S	Bend	trans	-79.4	-6.5	176.4	49.9	0	0	0	112.9
12	E	85.2	Confident	77.2	Confident	161 Å²	161	119 Å²	119	75%	0.752	70%	0.703	S	S	*	*			trans	-128.6	146.5	-176.6	-64.7	176.9	-164.8	0	109.6	S10	S10-E12 PolarHBondContact O-N 3.27Å
13	I	85.9	Confident	78.9	Confident	134 Å²	134	112.5 Å²	112.5	69%	0.687	67%	0.674	S	S	*	*			trans	-127.4	137	173.7	62.1	171.6	0	0	108.9
14	E	86.4	Confident	80.7	Confident	196 Å²	196	110.1 Å²	110.1	92%	0.916	66%	0.661	S	S	*	*			trans	-79.8	121.7	169	-67.9	-176	174.3	0	108.4
15	L	84.1	Confident	82.3	Confident	85 Å²	85	108.8 Å²	108.8	45%	0.445	64%	0.643	S	S	.	*			trans	-85.8	135.7	171.1	-85.5	134.3	0	0	109	V18 F23	L15-V18 HydrophobicContact CB-CG1 4.19Å; L15-V18 HydrophobicContact CD2-CG1 4.11Å; L15-F23 HydrophobicContact CD2-CE1 4.39Å; L15-F23 HydrophobicContact CD2-CZ 3.97Å; L15-F23 HydrophobicContact CD2-CE2 3.8Å; L15-F23 HydrophobicContact CD2-CD2 4.09Å; L15-F23 HydrophobicContact CD1-CZ 4.11Å; L15-F23 HydrophobicContact CD1-CE1 3.92Å; L15-F23 HydrophobicContact CD1-CD1 4.4Å
16	P	83.7	Confident	83.9	Confident	105 Å²	105	110 Å²	110	68%	0.682	63%	0.629	S	S	*	*			trans	-65.6	175.5	170.2	31.8	-35.7	0	0	110.1	V18	P16-V18 WeakPolarHBondContact O-CG1 3.33Å; P16-V18 PolarHBondContact O-N 2.99Å
17	D	86.1	Confident	85.3	Confident	181 Å²	181	105 Å²	105	97%	0.968	61%	0.606	S	S	*	*	S	Bend	trans	-51.7	102.8	178.7	-67.5	-50.7	0	0	111.6
18	V	86.4	Confident	86.7	Confident	70 Å²	70	106.5 Å²	106.5	42%	0.424	60%	0.597	S	S	.	*			trans	-138.2	141.2	-178.6	69.2	0	0	0	109.1	L15 P16 P20 F23	L15-V18 HydrophobicContact CB-CG1 4.19Å; L15-V18 HydrophobicContact CD2-CG1 4.11Å; P16-V18 WeakPolarHBondContact O-CG1 3.33Å; P16-V18 PolarHBondContact O-N 2.99Å; V18-P20 WeakPolarHBondContact O-CD 3.39Å; V18-F23 HydrophobicContact CG2-CB 4.33Å
19	E	92.4	Very high	87.7	Confident	139 Å²	139	106.6 Å²	106.6	65%	0.65	59%	0.589	S	S	*	*			trans	-71	122.4	174.1	-170.9	172.2	-174.4	0	109.9	A21 A22 F23	E19-A21 HydrophobicContact CG-CB 4.44Å; E19-A21 PolarHBondContact O-N 3.29Å; E19-A21 VanDerWaalsContact O-N 3.15Å; E19-A22 PolarHBondContact O-N 3.24Å; E19-A22 VanDerWaalsContact O-N 3.12Å; E19-A22 HydrophobicContact CB-CB 4.33Å; E19-F23 PolarHBondContact O-N 3.47Å
20	P	88.8	Confident	88.3	Confident	105 Å²	105	105.4 Å²	105.4	68%	0.682	58%	0.577	S	S	*	*	H	α-helix	trans	-58.2	-33.7	-175.3	-27.6	35.5	0	0	113.8	V18 F23 L24	V18-P20 WeakPolarHBondContact O-CD 3.39Å; P20-F23 PolarHBondContact O-N 2.96Å; P20-L24 WeakPolarHBondContact O-CB 3.49Å; P20-L24 PolarHBondContact O-N 3.43Å
21	A	91.3	Very high	88.8	Confident	65 Å²	65	110.1 Å²	110.1	54%	0.537	58%	0.584	S	S	.	*	H	α-helix	trans	-65.9	-41.8	179.3	0	0	0	0	112.3	E19 L24 A25	E19-A21 HydrophobicContact CG-CB 4.44Å; E19-A21 PolarHBondContact O-N 3.29Å; E19-A21 VanDerWaalsContact O-N 3.15Å; A21-L24 PolarHBondContact O-N 3.15Å; A21-A25 PolarHBondContact O-N 3.47Å; A21-A25 VanDerWaalsContact O-N 3.08Å
22	A	89.6	Confident	89.1	Confident	49 Å²	49	106.7 Å²	106.7	41%	0.405	57%	0.566	S	S	.	*	H	α-helix	trans	-66.3	-42.8	177.6	0	0	0	0	111.2	E19 L24 A25 L26	E19-A22 PolarHBondContact O-N 3.24Å; E19-A22 VanDerWaalsContact O-N 3.12Å; E19-A22 HydrophobicContact CB-CB 4.33Å; A22-L24 PolarHBondContact O-N 3.08Å; A22-A25 PolarHBondContact O-N 3Å; A22-L26 PolarHBondContact O-N 3.21Å; A22-L26 VanDerWaalsContact O-N 3.11Å; A22-L26 WeakPolarHBondContact O-CG 3.49Å
23	F	90.9	Very high	88.9	Confident	67 Å²	67	105.2 Å²	105.2	29%	0.294	56%	0.563	S	S	.	*	H	α-helix	trans	-64.8	-41.1	177.7	-171.5	-113.3	0	0	112.2	L15 V18 E19 P20 A25 L26 L27	L15-F23 HydrophobicContact CD2-CE1 4.39Å; L15-F23 HydrophobicContact CD2-CZ 3.97Å; L15-F23 HydrophobicContact CD2-CE2 3.8Å; L15-F23 HydrophobicContact CD2-CD2 4.09Å; L15-F23 HydrophobicContact CD1-CZ 4.11Å; L15-F23 HydrophobicContact CD1-CE1 3.92Å; L15-F23 HydrophobicContact CD1-CD1 4.4Å; V18-F23 HydrophobicContact CG2-CB 4.33Å; E19-F23 PolarHBondContact O-N 3.47Å; P20-F23 PolarHBondContact O-N 2.96Å; F23-A25 VanDerWaalsContact C-N 3.34Å; F23-A25 PolarHBondContact O-N 3.5Å; F23-L26 WeakPolarHBondContact O-CB 3.25Å; F23-L26 PolarHBondContact O-N 3.4Å; F23-L27 HydrophobicContact CZ-CD2 4.16Å; F23-L27 PolarHBondContact O-N 2.99Å; F23-L27 WeakPolarHBondContact O-CG 3.46Å; F23-L27 HydrophobicContact CZ-CG 4.31Å; F23-L27 HydrophobicContact CZ-CD1 4.35Å; F23-L27 HydrophobicContact CE1-CD2 4.31Å; F23-L27 HydrophobicContact CE1-CD1 3.68Å; F23-L27 HydrophobicContact CD1-CG 4.35Å; F23-L27 HydrophobicContact CD1-CD1 3.96Å; F23-L27 HydrophobicContact CE1-CG 4.08Å
24	L	90.1	Very high	88	Confident	91 Å²	91	105.1 Å²	105.1	48%	0.476	56%	0.56	S	S	.	*	H	α-helix	trans	-63	-40	176.7	-174.1	155.4	0	0	112.1	P20 A21 A22 L26 L27 K28	P20-L24 WeakPolarHBondContact O-CB 3.49Å; P20-L24 PolarHBondContact O-N 3.43Å; A21-L24 PolarHBondContact O-N 3.15Å; A22-L24 PolarHBondContact O-N 3.08Å; L24-L26 VanDerWaalsContact C-N 3.34Å; L24-L27 PolarHBondContact O-N 3.35Å; L24-K28 HydrophobicContact CD2-CD 3.72Å; L24-K28 HydrophobicContact CD2-CG 4.19Å; L24-K28 WeakPolarHBondContact O-CG 3.37Å; L24-K28 PolarHBondContact O-N 3.46Å
25	A	90.4	Very high	86.7	Confident	36 Å²	36	103.9 Å²	103.9	30%	0.298	57%	0.566	S	S	.	*	H	α-helix	trans	-61.6	-41.6	174	0	0	0	0	111.8	A21 A22 F23 L27 K28 F29	A21-A25 PolarHBondContact O-N 3.47Å; A21-A25 VanDerWaalsContact O-N 3.08Å; A22-A25 PolarHBondContact O-N 3Å; F23-A25 VanDerWaalsContact C-N 3.34Å; F23-A25 PolarHBondContact O-N 3.5Å; A25-L27 VanDerWaalsContact C-N 3.33Å; A25-L27 PolarHBondContact O-N 3.47Å; A25-K28 PolarHBondContact O-N 3.34Å; A25-F29 WeakPolarHBondContact O-CB 3.46Å; A25-F29 PolarHBondContact O-N 3.15Å
26	L	90.8	Very high	86.8	Confident	110 Å²	110	104.9 Å²	104.9	58%	0.576	57%	0.572	S	S	*	*	H	α-helix	trans	-62.3	-39.5	174.8	-67.8	174.1	0	0	112.5	A22 F23 L24 F29 L30	A22-L26 PolarHBondContact O-N 3.21Å; A22-L26 VanDerWaalsContact O-N 3.11Å; A22-L26 WeakPolarHBondContact O-CG 3.49Å; F23-L26 WeakPolarHBondContact O-CB 3.25Å; F23-L26 PolarHBondContact O-N 3.4Å; L24-L26 VanDerWaalsContact C-N 3.34Å; L26-F29 PolarHBondContact O-N 3.49Å; L26-L30 VanDerWaalsContact O-CB 3.31Å; L26-L30 WeakPolarHBondContact O-CB 3.28Å; L26-L30 PolarHBondContact O-N 2.96Å
27	L	92.1	Very high	86.9	Confident	69 Å²	69	104.8 Å²	104.8	36%	0.361	57%	0.566	S	S	.	*	H	α-helix	trans	-64.8	-44.2	175.6	-68.4	176.1	0	0	111.4	F23 L24 A25 F29 L30 Y31	F23-L27 HydrophobicContact CZ-CD2 4.16Å; F23-L27 PolarHBondContact O-N 2.99Å; F23-L27 WeakPolarHBondContact O-CG 3.46Å; F23-L27 HydrophobicContact CZ-CG 4.31Å; F23-L27 HydrophobicContact CZ-CD1 4.35Å; F23-L27 HydrophobicContact CE1-CD2 4.31Å; F23-L27 HydrophobicContact CE1-CD1 3.68Å; F23-L27 HydrophobicContact CD1-CG 4.35Å; F23-L27 HydrophobicContact CD1-CD1 3.96Å; F23-L27 HydrophobicContact CE1-CG 4.08Å; L24-L27 PolarHBondContact O-N 3.35Å; A25-L27 VanDerWaalsContact C-N 3.33Å; A25-L27 PolarHBondContact O-N 3.47Å; L27-F29 VanDerWaalsContact C-N 3.34Å; L27-F29 PolarHBondContact O-N 3.2Å; L27-L30 PolarHBondContact O-N 2.82Å; L27-Y31 PolarHBondContact O-N 2.65Å; L27-Y31 HydrophobicContact CD2-CE2 4.05Å; L27-Y31 WeakPolarHBondContact O-CD2 3.46Å; L27-Y31 WeakPolarHBondContact O-CB 3.34Å; L27-Y31 HydrophobicContact CD2-CD2 4.48Å; L27-Y31 VanDerWaalsContact O-CD2 3.25Å
28	K	91.8	Very high	87	Confident	108 Å²	108	100.6 Å²	100.6	47%	0.47	54%	0.544	S	S	.	.	H	α-helix	trans	-59.9	-45.4	175.8	-74.9	177.6	171.6	172	111.8	L24 A25 L30 Y31 S32 D33 E34	L24-K28 HydrophobicContact CD2-CD 3.72Å; L24-K28 HydrophobicContact CD2-CG 4.19Å; L24-K28 WeakPolarHBondContact O-CG 3.37Å; L24-K28 PolarHBondContact O-N 3.46Å; A25-K28 PolarHBondContact O-N 3.34Å; K28-L30 VanDerWaalsContact C-N 3.35Å; K28-L30 PolarHBondContact O-N 3.09Å; K28-Y31 PolarHBondContact O-N 3.45Å; K28-S32 WeakPolarHBondContact O-CA 3.27Å; K28-S32 WeakPolarHBondContact O-CB 3.48Å; K28-S32 PolarHBondContact O-N 2.94Å; K28-D33 PolarHBondContact O-N 3.47Å; K28-E34 CarbonylContact C-O 3.33Å
29	F	91.5	Very high	87	Confident	101 Å²	101	102.4 Å²	102.4	44%	0.443	55%	0.551	S	S	.	*	H	α-helix	trans	-59.1	-47.2	175.1	175.3	-107	0	0	111.3	A25 L26 L27 Y31 D33 E34 V35	A25-F29 WeakPolarHBondContact O-CB 3.46Å; A25-F29 PolarHBondContact O-N 3.15Å; L26-F29 PolarHBondContact O-N 3.49Å; L27-F29 VanDerWaalsContact C-N 3.34Å; L27-F29 PolarHBondContact O-N 3.2Å; F29-Y31 PolarHBondContact O-N 2.91Å; F29-D33 VanDerWaalsContact O-CA 3.28Å; F29-D33 WeakPolarHBondContact O-CA 3.31Å; F29-D33 PolarHBondContact O-N 3.44Å; F29-E34 VanDerWaalsContact CA-O 3.27Å; F29-E34 WeakPolarHBondContact CA-O 3.43Å; F29-E34 PolarHBondContact N-O 3.11Å; F29-E34 VanDerWaalsContact N-O 3.09Å; F29-V35 HydrophobicContact CD2-CG1 4.36Å
30	L	91.8	Very high	86.7	Confident	121 Å²	121	100.1 Å²	100.1	63%	0.634	54%	0.544	S	S	*	.	H	α-helix	trans	-64.8	-37	-177.4	-174.6	64	0	0	113.5	L26 L27 K28	L26-L30 VanDerWaalsContact O-CB 3.31Å; L26-L30 WeakPolarHBondContact O-CB 3.28Å; L26-L30 PolarHBondContact O-N 2.96Å; L27-L30 PolarHBondContact O-N 2.82Å; K28-L30 VanDerWaalsContact C-N 3.35Å; K28-L30 PolarHBondContact O-N 3.09Å
31	Y	91.9	Very high	86.5	Confident	177 Å²	177	99.8 Å²	99.8	69%	0.694	54%	0.535	S	S	*	.	H	α-helix	trans	-103.6	-13.1	-172.2	-72.5	-73.6	0	0	114.5	L27 K28 F29	L27-Y31 PolarHBondContact O-N 2.65Å; L27-Y31 HydrophobicContact CD2-CE2 4.05Å; L27-Y31 WeakPolarHBondContact O-CD2 3.46Å; L27-Y31 WeakPolarHBondContact O-CB 3.34Å; L27-Y31 HydrophobicContact CD2-CD2 4.48Å; L27-Y31 VanDerWaalsContact O-CD2 3.25Å; K28-Y31 PolarHBondContact O-N 3.45Å; F29-Y31 PolarHBondContact O-N 2.91Å
32	S	89.4	Confident	86.2	Confident	71 Å²	71	102.3 Å²	102.3	50%	0.497	54%	0.535	S	S	.	.	H	α-helix	trans	-136.4	-5.5	-175.4	-54.8	0	0	0	113.7	K28 E34	K28-S32 WeakPolarHBondContact O-CA 3.27Å; K28-S32 WeakPolarHBondContact O-CB 3.48Å; K28-S32 PolarHBondContact O-N 2.94Å; S32-E34 PolarHBondContact O-N 3.12Å; S32-E34 VanDerWaalsContact O-N 3.15Å
33	D	80.7	Confident	86	Confident	130 Å²	130	106.4 Å²	106.4	70%	0.695	55%	0.545	S	S	*	.	S	Bend	trans	56	22.3	-172.4	-152	18.7	0	0	112.6	K28 F29	K28-D33 PolarHBondContact O-N 3.47Å; F29-D33 VanDerWaalsContact O-CA 3.28Å; F29-D33 WeakPolarHBondContact O-CA 3.31Å; F29-D33 PolarHBondContact O-N 3.44Å
34	E	66.9	Low	85.5	Confident	131 Å²	131	109.7 Å²	109.7	61%	0.612	57%	0.566	S	S	*	*			trans	-101.9	125.1	177.7	-67.4	-178	173.9	0	108.8	K28 F29 S32	K28-E34 CarbonylContact C-O 3.33Å; F29-E34 VanDerWaalsContact CA-O 3.27Å; F29-E34 WeakPolarHBondContact CA-O 3.43Å; F29-E34 PolarHBondContact N-O 3.11Å; F29-E34 VanDerWaalsContact N-O 3.09Å; S32-E34 PolarHBondContact O-N 3.12Å; S32-E34 VanDerWaalsContact O-N 3.15Å
35	V	59.1	Low	85.1	Confident	171 Å²	171	111.4 Å²	111.4	100%	1.036	57%	0.574	S	S	*	*			trans	-99.8	0	177.7	-125.1	0	0	0	111.1	F29	F29-V35 HydrophobicContact CD2-CG1 4.36Å

Retrieved 35 of 35 residues in 76 ms (Link to these results)

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