A0A087X4E9_POEFO Loading...

Tyrosine-protein kinase

AlphaFold DB , UniProt , Accession A0A087X4E9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 637 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.8Very low82Confident230 Ų23074.4 Ų74.4100%1.13339%0.391SS*.  0131.40-69.4-176.9-122.900106.1D3M1-D3 PolarHBondContact O-N 2.84Å
2S52.8Low83Confident100 Ų10070.9 Ų70.970%0.69937%0.37SS*.  trans-72.3108.8-17347.20000110.8N4S2-N4 PolarHBondContact O-N 2.69Å
3D70.5Confident83.6Confident113 Ų11365.6 Ų65.660%0.60434%0.342SS*.  trans-72.847.6176.3-69.9-39.2000112.8M1 T33M1-D3 PolarHBondContact O-N 2.84Å; D3-T33 WeakPolarHBondContact O-CA 3.48Å; D3-T33 WeakPolarHBondContact O-CB 3.48Å
4N84.1Confident83.5Confident66 Ų6663.1 Ų63.135%0.35333%0.333SS..EExtended strand (participates in β ladder)trans-84.1114.5175.4-65.7-5.7000108.6S2 I31S2-N4 PolarHBondContact O-N 2.69Å; N4-I31 HydrophobicContact CB-CG2 4.15Å; N4-I31 WeakPolarHBondContact OD1-CG2 3.47Å
5L88.8Confident82.6Confident62 Ų6260.5 Ų60.533%0.32532%0.319SS..EExtended strand (participates in β ladder)trans-80.3-41.1177.1-65.2177000112L32 Q34 L110L5-L32 HydrophobicContact CB-CG 4.39Å; L5-L32 WeakPolarHBondContact CB-O 3.37Å; L5-L32 PolarHBondContact N-O 3.23Å; L5-Q34 HydrophobicContact CD1-CG 4.04Å; L5-Q34 HydrophobicContact CD2-CG 4.31Å; L5-Q34 HydrophobicContact CG-CG 4.35Å; L5-L110 HydrophobicContact CD1-CD1 3.75Å; L5-L110 HydrophobicContact CD1-CD2 4.05Å
6M93.6Very high81.4Confident41 Ų4157.8 Ų57.820%0.20230%0.303CS..EExtended strand (participates in β ladder)trans-150.7147.9177.8-60.9-177.976.300109.5L32 W103 K106M6-L32 HydrophobicContact CB-CB 4.19Å; M6-L32 HydrophobicContact CB-CD2 4.44Å; M6-L32 HydrophobicContact CG-CD2 4.44Å; M6-L32 PolarHBondContact N-O 3.12Å; M6-L32 PolarHBondContact O-N 2.88Å; M6-L32 HydrophobicContact SD-CD2 4.31Å; M6-W103 HydrophobicContact CB-CH2 4.05Å; M6-W103 HydrophobicContact CB-CZ2 3.68Å; M6-W103 VanDerWaalsContact CE-CD1 3.43Å; M6-W103 HydrophobicContact CE-CD2 4.22Å; M6-W103 HydrophobicContact CE-CG 3.94Å; M6-W103 HydrophobicContact SD-CD2 4.4Å; M6-W103 HydrophobicContact SD-CG 4.45Å; M6-K106 HydrophobicContact CG-CG 4.37Å; M6-K106 HydrophobicContact SD-CB 3.51Å; M6-K106 VanDerWaalsContact SD-CB 3.51Å; M6-K106 HydrophobicContact SD-CG 3.59Å; M6-K106 VanDerWaalsContact SD-CG 3.59Å
7E93.9Very high80.2Confident101 Ų10164.7 Ų64.747%0.47233%0.331SS..EExtended strand (participates in β ladder)trans-141.1142.8168.863-180-165.900110.5W29 F30 I31E7-W29 PolarHBondContact OE2-NE1 2.8Å; E7-F30 WeakPolarHBondContact CA-O 3.16Å; E7-F30 WeakPolarHBondContact CB-O 3.49Å; E7-I31 HydrophobicContact CB-CG1 4.12Å
8E94.9Very high79Confident54 Ų5467.6 Ų67.625%0.25234%0.341SS..EExtended strand (participates in β ladder)trans-162.3153.1-176.8-173.955.7-8900110.3F10 F30 I99 W103E8-F10 HydrophobicContact CB-CD2 4.37Å; E8-F10 HydrophobicContact CB-CE1 4.27Å; E8-F10 HydrophobicContact CB-CE2 3.77Å; E8-F10 HydrophobicContact CB-CZ 3.73Å; E8-F10 HydrophobicContact CG-CD1 4.1Å; E8-F10 HydrophobicContact CG-CE1 3.58Å; E8-F10 HydrophobicContact CG-CE2 4.03Å; E8-F10 HydrophobicContact CG-CZ 3.54Å; E8-F30 PolarHBondContact N-O 3.45Å; E8-F30 PolarHBondContact O-N 2.96Å; E8-I99 HydrophobicContact CG-CG2 3.81Å; E8-W103 HydrophobicContact CB-CZ2 3.5Å
9I93.4Very high77.4Confident27 Ų2772 Ų7214%0.13836%0.357CS..EExtended strand (participates in β ladder)trans-91.8119.5173.2-60.9159.5000108.9E27 R28 W29 F42I9-E27 HydrophobicContact CG2-CB 4.3Å; I9-R28 WeakPolarHBondContact CA-O 2.86Å; I9-W29 HydrophobicContact CG1-CE3 4.39Å; I9-F42 HydrophobicContact CD1-CD1 4.3Å; I9-F42 HydrophobicContact CD1-CD2 4.15Å; I9-F42 HydrophobicContact CD1-CE1 3.78Å; I9-F42 HydrophobicContact CD1-CE2 3.6Å; I9-F42 HydrophobicContact CD1-CG 4.47Å; I9-F42 HydrophobicContact CD1-CZ 3.4Å; I9-F42 HydrophobicContact CG1-CD2 4.4Å; I9-F42 HydrophobicContact CG1-CE1 4.49Å; I9-F42 HydrophobicContact CG1-CE2 4.32Å; I9-F42 HydrophobicContact CG1-CG 4.5Å; I9-F42 HydrophobicContact CG1-CZ 4.37Å; I9-F42 HydrophobicContact CG2-CD1 3.94Å; I9-F42 HydrophobicContact CG2-CE1 4.18Å; I9-F42 HydrophobicContact CG2-CG 4.42Å
10F95.2Very high76Confident2 Ų273.7 Ų73.71%0.00937%0.372CS..EExtended strand (participates in β ladder)trans-123.3154.7177.4-64.7-55.8000112.1E8 E27 R28 F30 F81 I92 F93 A94 I99 W103E8-F10 HydrophobicContact CB-CD2 4.37Å; E8-F10 HydrophobicContact CB-CE1 4.27Å; E8-F10 HydrophobicContact CB-CE2 3.77Å; E8-F10 HydrophobicContact CB-CZ 3.73Å; E8-F10 HydrophobicContact CG-CD1 4.1Å; E8-F10 HydrophobicContact CG-CE1 3.58Å; E8-F10 HydrophobicContact CG-CE2 4.03Å; E8-F10 HydrophobicContact CG-CZ 3.54Å; F10-E27 CarbonylContact O-C 3.58Å; F10-E27 WeakPolarHBondContact O-CA 3.43Å; F10-R28 PolarHBondContact N-O 3.38Å; F10-R28 PolarHBondContact O-N 2.82Å; F10-F30 HydrophobicContact CB-CD2 3.72Å; F10-F30 HydrophobicContact CB-CE2 3.75Å; F10-F30 HydrophobicContact CD2-CB 3.86Å; F10-F30 AromaticContact CD2-CD2 3.64Å; F10-F30 HydrophobicContact CD2-CD2 3.64Å; F10-F30 HydrophobicContact CD2-CE2 4.29Å; F10-F30 AromaticContact CD2-CG 3.8Å; F10-F30 HydrophobicContact CD2-CG 3.8Å; F10-F30 HydrophobicContact CE2-CB 4.32Å; F10-F30 HydrophobicContact CG-CD2 4.15Å; F10-F81 HydrophobicContact CE2-CZ 4.44Å; F10-F81 HydrophobicContact CZ-CE1 4.44Å; F10-I92 HydrophobicContact CB-CG2 3.37Å; F10-I92 HydrophobicContact CD1-CG2 4.14Å; F10-I92 HydrophobicContact CD2-CG2 3.67Å; F10-I92 HydrophobicContact CE2-CG2 4.46Å; F10-I92 HydrophobicContact CG-CG2 3.47Å; F10-I92 VanDerWaalsContact CG-CG2 3.47Å; F10-F93 WeakPolarHBondContact CD1-O 3.41Å; F10-A94 HydrophobicContact CD1-CB 4.1Å; F10-A94 HydrophobicContact CE1-CB 3.67Å; F10-I99 HydrophobicContact CE1-CG2 3.56Å; F10-I99 HydrophobicContact CZ-CG2 3.78Å; F10-W103 AromaticContact CE2-CD2 3.56Å; F10-W103 HydrophobicContact CE2-CD2 3.56Å; F10-W103 AromaticContact CE2-CE2 3.53Å; F10-W103 AromaticContact CE2-CE3 3.84Å; F10-W103 HydrophobicContact CE2-CE3 3.84Å; F10-W103 HydrophobicContact CE2-CG 4.05Å; F10-W103 HydrophobicContact CE2-CH2 4.09Å; F10-W103 AromaticContact CE2-CZ2 3.82Å; F10-W103 HydrophobicContact CE2-CZ2 3.82Å; F10-W103 HydrophobicContact CE2-CZ3 4.1Å; F10-W103 AromaticContact CE2-NE1 3.95Å; F10-W103 HydrophobicContact CZ-CB 4.44Å; F10-W103 AromaticContact CZ-CD1 3.61Å; F10-W103 AromaticContact CZ-CD2 3.69Å; F10-W103 HydrophobicContact CZ-CD2 3.69Å; F10-W103 AromaticContact CZ-CE2 3.64Å; F10-W103 HydrophobicContact CZ-CE3 4.4Å; F10-W103 AromaticContact CZ-CG 3.68Å; F10-W103 HydrophobicContact CZ-CG 3.68Å; F10-W103 HydrophobicContact CZ-CZ2 4.32Å; F10-W103 AromaticContact CZ-NE1 3.56Å
11I93.9Very high74.9Confident22 Ų2272 Ų7211%0.11337%0.367CS..EExtended strand (participates in β ladder)trans-81.8127.5164.9-58.4168.6000107.7Y25 E27 E76 I92 F93I11-Y25 HydrophobicContact CG2-CD1 4.13Å; I11-Y25 HydrophobicContact CG2-CG 4.44Å; I11-E27 HydrophobicContact CG1-CG 4.01Å; I11-E76 HydrophobicContact CD1-CB 4.09Å; I11-I92 CarbonylContact O-C 3.56Å; I11-I92 WeakPolarHBondContact O-CA 3.15Å; I11-F93 HydrophobicContact CB-CB 4.16Å; I11-F93 HydrophobicContact CB-CD2 4.24Å; I11-F93 HydrophobicContact CG2-CD2 4.14Å; I11-F93 PolarHBondContact N-O 2.86Å; I11-F93 WeakPolarHBondContact O-CD2 3.39Å; I11-F93 PolarHBondContact O-N 2.85Å
12K93.8Very high75.5Confident33 Ų3366.2 Ų66.214%0.14335%0.346CS..EExtended strand (participates in β ladder)trans-104.1128174.9177.6176.5-179.8-100.10109.9Y25 K26 R28 F30 Y39 L90K12-Y25 WeakPolarHBondContact O-CA 3.23Å; K12-K26 PolarHBondContact N-O 3.06Å; K12-K26 PolarHBondContact O-N 2.95Å; K12-K26 VanDerWaalsContact O-N 3.08Å; K12-R28 HydrophobicContact CB-CG 4.01Å; K12-R28 HydrophobicContact CD-CG 4.49Å; K12-F30 HydrophobicContact CB-CE2 4.31Å; K12-F30 HydrophobicContact CB-CZ 4.16Å; K12-F30 HydrophobicContact CD-CZ 4.25Å; K12-F30 HydrophobicContact CG-CZ 4.45Å; K12-Y39 HydrophobicContact CD-CD2 3.87Å; K12-Y39 HydrophobicContact CD-CE1 4.38Å; K12-Y39 HydrophobicContact CD-CE2 3.63Å; K12-Y39 HydrophobicContact CD-CG 4.35Å; K12-Y39 WeakPolarHBondContact CE-OH 3.21Å; K12-Y39 PolarHBondContact NZ-OH 3.25Å; K12-L90 HydrophobicContact CD-CD1 3.88Å; K12-L90 HydrophobicContact CG-CD1 3.91Å
13R90.6Very high76.6Confident2 Ų264.3 Ų64.31%0.00833%0.328CS..EExtended strand (participates in β ladder)trans-75.8138.5167.3-153.7170.4176.4-125.9-6.1109.7Q15 L23 N24 Y25 Y91 F93 W126R13-Q15 PolarHBondContact O-N 3.44Å; R13-L23 HydrophobicContact CG-CD2 3.91Å; R13-L23 VanDerWaalsContact NH2-CD1 3.33Å; R13-N24 CarbonylContact C-O 3.56Å; R13-N24 WeakPolarHBondContact CA-O 3.26Å; R13-Y25 HydrophobicContact CB-CD1 4.46Å; R13-Y25 HydrophobicContact CB-CE1 4.26Å; R13-Y25 HydrophobicContact CG-CD1 4.25Å; R13-Y25 HydrophobicContact CG-CE1 3.72Å; R13-Y25 PolarHBondContact NE-OH 3.44Å; R13-Y25 VanDerWaalsContact NE-OH 3.17Å; R13-Y91 HydrophobicContact CB-CD2 4.37Å; R13-Y91 PolarHBondContact N-O 3.09Å; R13-F93 HydrophobicContact CB-CE2 4.02Å; R13-W126 PolarHBondContact NH1-O 2.84Å
14S83.3Confident77.2Confident31 Ų3162.7 Ų62.722%0.21732%0.319CS..  trans-59.9136.6166.659.70000110.2Q16 P22 N24S14-Q16 PolarHBondContact O-N 3.43Å; S14-Q16 VanDerWaalsContact O-N 3.13Å; S14-P22 PolarHBondContact OG-O 3.16Å; S14-N24 PolarHBondContact N-O 2.9Å; S14-N24 PolarHBondContact OG-N 3.39Å; S14-N24 PolarHBondContact OG-O 3.17Å
15Q69.1Low77.4Confident24 Ų2462.4 Ų62.411%0.11231%0.314CS..  trans-73.91-175.9-75.6173.9-19.300114.4R13 Y85 K139R13-Q15 PolarHBondContact O-N 3.44Å; Q15-Y85 PolarHBondContact NE2-OH 3.29Å; Q15-Y85 PolarHBondContact OE1-OH 2.81Å; Q15-K139 PolarHBondContact O-NZ 3.26Å
16Q63.5Low77.4Confident16 Ų1664.3 Ų64.38%0.07532%0.32CS..  trans41.681.9-174.8-68.2-173.4-58.300112.2S14 K18 S21 L23 K139S14-Q16 PolarHBondContact O-N 3.43Å; S14-Q16 VanDerWaalsContact O-N 3.13Å; Q16-K18 PolarHBondContact O-N 3.17Å; Q16-S21 PolarHBondContact NE2-O 3.19Å; Q16-L23 HydrophobicContact CG-CD2 3.85Å; Q16-L23 HydrophobicContact CG-CG 4.09Å; Q16-L23 VanDerWaalsContact NE2-CG 3.35Å; Q16-K139 PolarHBondContact O-NZ 3.36Å; Q16-K139 VanDerWaalsContact O-NZ 3.07Å
17K61.6Low77.4Confident176 Ų17665.9 Ų65.977%0.76533%0.326SS*.SBendtrans-70.1-21.5179.3-66.6-169.5177-168.80112.3
18K58.2Low77.4Confident117 Ų11762.6 Ų62.651%0.50931%0.309SS..SBendtrans-129.7155.4171.7-60.5-179.2179.3-178.80109.7Q16 T20 S21 T530Q16-K18 PolarHBondContact O-N 3.17Å; K18-T20 PolarHBondContact O-N 2.69Å; K18-S21 PolarHBondContact N-OG 3.29Å; K18-S21 WeakPolarHBondContact O-CB 3.37Å; K18-S21 PolarHBondContact O-N 2.87Å; K18-S21 VanDerWaalsContact O-N 3.11Å; K18-S21 PolarHBondContact O-OG 2.95Å; K18-T530 PolarHBondContact NZ-OG1 3.07Å
19K48.6Very low77.3Confident151 Ų15162.5 Ų62.566%0.65731%0.307SS*.THydrogen-bonded Turntrans-57.7-29.9-178.5-161.4179.2-174.3179.80113D128K19-D128 WeakPolarHBondContact CE-O 3.34Å
20T48.9Very low77.5Confident106 Ų10661.2 Ų61.265%0.6530%0.3SS*.THydrogen-bonded Turntrans-92.3-5-178.753.40000114.4K18K18-T20 PolarHBondContact O-N 2.69Å
21S53.7Low77.5Confident38 Ų3861.3 Ų61.327%0.26630%0.301SS..SBendtrans-65.4128.5-179.7-61.30000110.7Q16 K18Q16-S21 PolarHBondContact NE2-O 3.19Å; K18-S21 PolarHBondContact N-OG 3.29Å; K18-S21 WeakPolarHBondContact O-CB 3.37Å; K18-S21 PolarHBondContact O-N 2.87Å; K18-S21 VanDerWaalsContact O-N 3.11Å; K18-S21 PolarHBondContact O-OG 2.95Å
22P53.8Low77.5Confident109 Ų10960.3 Ų60.371%0.70830%0.296SS*.  trans-63.1143.3-179.424.4-33.2000110.9S14 N24S14-P22 PolarHBondContact OG-O 3.16Å; P22-N24 PolarHBondContact O-N 2.86Å
23L74.8Confident77.5Confident60 Ų6060 Ų6031%0.31430%0.296SS..  trans-76.8103.8176.5-86.1159.2000110.3R13 Q16 Y25 V127R13-L23 HydrophobicContact CG-CD2 3.91Å; R13-L23 VanDerWaalsContact NH2-CD1 3.33Å; Q16-L23 HydrophobicContact CG-CD2 3.85Å; Q16-L23 HydrophobicContact CG-CG 4.09Å; Q16-L23 VanDerWaalsContact NE2-CG 3.35Å; L23-Y25 HydrophobicContact CB-CE2 4.26Å; L23-V127 HydrophobicContact CD1-CG1 4.27Å
24N82.6Confident77.5Confident79 Ų7966.4 Ų66.442%0.42233%0.327SS..  trans-104.8141.2178.1-158.9-27.3000110.8R13 S14 P22 K26R13-N24 CarbonylContact C-O 3.56Å; R13-N24 WeakPolarHBondContact CA-O 3.26Å; S14-N24 PolarHBondContact N-O 2.9Å; S14-N24 PolarHBondContact OG-N 3.39Å; S14-N24 PolarHBondContact OG-O 3.17Å; P22-N24 PolarHBondContact O-N 2.86Å; N24-K26 WeakPolarHBondContact ND2-CE 3.33Å; N24-K26 WeakPolarHBondContact OD1-CG 3.48Å
25Y88.9Confident78Confident59 Ų5972.1 Ų72.123%0.23135%0.35CS..EExtended strand (participates in β ladder)trans-121.6117.8177.2-64.7-98.9000107.2I11 K12 R13 L23 F93I11-Y25 HydrophobicContact CG2-CD1 4.13Å; I11-Y25 HydrophobicContact CG2-CG 4.44Å; K12-Y25 WeakPolarHBondContact O-CA 3.23Å; R13-Y25 HydrophobicContact CB-CD1 4.46Å; R13-Y25 HydrophobicContact CB-CE1 4.26Å; R13-Y25 HydrophobicContact CG-CD1 4.25Å; R13-Y25 HydrophobicContact CG-CE1 3.72Å; R13-Y25 PolarHBondContact NE-OH 3.44Å; R13-Y25 VanDerWaalsContact NE-OH 3.17Å; L23-Y25 HydrophobicContact CB-CE2 4.26Å; Y25-F93 HydrophobicContact CD1-CD2 4.31Å; Y25-F93 AromaticContact CD1-CE2 3.7Å; Y25-F93 HydrophobicContact CD1-CE2 3.7Å; Y25-F93 HydrophobicContact CD1-CZ 4.21Å; Y25-F93 HydrophobicContact CE1-CD2 4.5Å; Y25-F93 AromaticContact CE1-CE2 3.53Å; Y25-F93 HydrophobicContact CE1-CE2 3.53Å; Y25-F93 AromaticContact CE1-CZ 3.59Å; Y25-F93 HydrophobicContact CE1-CZ 3.59Å
26K89.4Confident79.2Confident103 Ų10374.8 Ų74.845%0.44836%0.361SS..EExtended strand (participates in β ladder)trans-130.9138.3179.7-63.6-166.3173.1-169.70111.4K12 N24 R28K12-K26 PolarHBondContact N-O 3.06Å; K12-K26 PolarHBondContact O-N 2.95Å; K12-K26 VanDerWaalsContact O-N 3.08Å; N24-K26 WeakPolarHBondContact ND2-CE 3.33Å; N24-K26 WeakPolarHBondContact OD1-CG 3.48Å; K26-R28 VanDerWaalsContact CD-NH2 3.3Å
27E92.7Very high80.7Confident73 Ų7374 Ų7434%0.34136%0.358SS..EExtended strand (participates in β ladder)trans-65.4135.6169.4-69.1-167.2125.900110.8I9 F10 I11 F42I9-E27 HydrophobicContact CG2-CB 4.3Å; F10-E27 CarbonylContact O-C 3.58Å; F10-E27 WeakPolarHBondContact O-CA 3.43Å; I11-E27 HydrophobicContact CG1-CG 4.01Å; E27-F42 HydrophobicContact CB-CD1 4.26Å
28R94.1Very high82.3Confident32 Ų3265.9 Ų65.912%0.12132%0.323CS..EExtended strand (participates in β ladder)trans-141.3142.4-178.6-63.8-66.3177.7-114.721.1109.3I9 F10 K12 K26 F30 Y39 Y40 D41I9-R28 WeakPolarHBondContact CA-O 2.86Å; F10-R28 PolarHBondContact N-O 3.38Å; F10-R28 PolarHBondContact O-N 2.82Å; K12-R28 HydrophobicContact CB-CG 4.01Å; K12-R28 HydrophobicContact CD-CG 4.49Å; K26-R28 VanDerWaalsContact CD-NH2 3.3Å; R28-F30 HydrophobicContact CB-CD2 4.03Å; R28-F30 HydrophobicContact CB-CE2 3.65Å; R28-F30 WeakPolarHBondContact O-CD2 3.27Å; R28-F30 PolarHBondContact O-N 2.91Å; R28-Y39 HydrophobicContact CG-CD2 4.37Å; R28-Y40 WeakPolarHBondContact CA-O 3.4Å; R28-Y40 WeakPolarHBondContact CB-O 3.17Å; R28-Y40 WeakPolarHBondContact CD-O 3.26Å; R28-D41 IonicContact CZ-OD1 2.75Å; R28-D41 IonicContact NE-OD1 2.73Å; R28-D41 PolarHBondContact NE-OD1 3.26Å; R28-D41 IonicContact NH1-OD1 3.59Å; R28-D41 PolarHBondContact NH1-OD1 2.73Å; R28-D41 IonicContact NH2-OD1 2.69Å; R28-D41 PolarHBondContact NH2-OD1 3.45Å
29W94Very high84Confident53 Ų5361.3 Ų61.320%0.20130%0.303CS..EExtended strand (participates in β ladder)trans-83.7111.7171.6-167.7-49.6000108.2E7 I9 Y39 Y40 F42 R49E7-W29 PolarHBondContact OE2-NE1 2.8Å; I9-W29 HydrophobicContact CG1-CE3 4.39Å; W29-Y39 CarbonylContact O-C 3.55Å; W29-Y39 VanDerWaalsContact O-CA 3.29Å; W29-Y39 WeakPolarHBondContact O-CA 3.37Å; W29-Y40 PolarHBondContact N-O 3.4Å; W29-Y40 WeakPolarHBondContact O-CD2 3.19Å; W29-Y40 PolarHBondContact O-N 3.14Å; W29-F42 AromaticContact CE3-CD2 3.71Å; W29-F42 HydrophobicContact CE3-CD2 3.71Å; W29-F42 AromaticContact CE3-CE2 3.92Å; W29-F42 HydrophobicContact CE3-CE2 3.92Å; W29-F42 HydrophobicContact CZ3-CD2 4.27Å; W29-F42 HydrophobicContact CZ3-CE2 4.04Å; W29-R49 HydrophobicContact CB-CG 4.49Å; W29-R49 HydrophobicContact CD2-CB 4.39Å; W29-R49 HydrophobicContact CE3-CB 4.22Å; W29-R49 HydrophobicContact CG-CG 4.47Å
30F96.1Very high86.1Confident0 Ų056.4 Ų56.40%028%0.28CS..EExtended strand (participates in β ladder)trans-93.8139.5176.8-78.2-103000110.7E7 E8 F10 K12 R28 I37 A38 Y39 I92 W103E7-F30 WeakPolarHBondContact CA-O 3.16Å; E7-F30 WeakPolarHBondContact CB-O 3.49Å; E8-F30 PolarHBondContact N-O 3.45Å; E8-F30 PolarHBondContact O-N 2.96Å; F10-F30 HydrophobicContact CB-CD2 3.72Å; F10-F30 HydrophobicContact CB-CE2 3.75Å; F10-F30 HydrophobicContact CD2-CB 3.86Å; F10-F30 AromaticContact CD2-CD2 3.64Å; F10-F30 HydrophobicContact CD2-CD2 3.64Å; F10-F30 HydrophobicContact CD2-CE2 4.29Å; F10-F30 AromaticContact CD2-CG 3.8Å; F10-F30 HydrophobicContact CD2-CG 3.8Å; F10-F30 HydrophobicContact CE2-CB 4.32Å; F10-F30 HydrophobicContact CG-CD2 4.15Å; K12-F30 HydrophobicContact CB-CE2 4.31Å; K12-F30 HydrophobicContact CB-CZ 4.16Å; K12-F30 HydrophobicContact CD-CZ 4.25Å; K12-F30 HydrophobicContact CG-CZ 4.45Å; R28-F30 HydrophobicContact CB-CD2 4.03Å; R28-F30 HydrophobicContact CB-CE2 3.65Å; R28-F30 WeakPolarHBondContact O-CD2 3.27Å; R28-F30 PolarHBondContact O-N 2.91Å; F30-I37 HydrophobicContact CD1-CD1 3.87Å; F30-I37 HydrophobicContact CD1-CG1 4.02Å; F30-I37 HydrophobicContact CE1-CD1 4.49Å; F30-A38 CarbonylContact C-O 3.45Å; F30-A38 WeakPolarHBondContact CA-O 3.38Å; F30-Y39 HydrophobicContact CD1-CD1 4.39Å; F30-Y39 HydrophobicContact CD1-CG 4.43Å; F30-Y39 AromaticContact CE1-CD1 3.76Å; F30-Y39 HydrophobicContact CE1-CD1 3.76Å; F30-Y39 AromaticContact CE1-CG 3.91Å; F30-Y39 HydrophobicContact CE1-CG 3.91Å; F30-Y39 HydrophobicContact CZ-CD1 4.22Å; F30-Y39 HydrophobicContact CZ-CG 4.04Å; F30-I92 HydrophobicContact CD1-CD1 4.29Å; F30-I92 HydrophobicContact CE1-CD1 3.62Å; F30-I92 HydrophobicContact CE1-CG1 4.26Å; F30-I92 HydrophobicContact CE2-CG2 4.37Å; F30-I92 HydrophobicContact CZ-CD1 3.93Å; F30-I92 HydrophobicContact CZ-CG1 4.06Å; F30-I92 HydrophobicContact CZ-CG2 4.34Å; F30-W103 HydrophobicContact CB-CH2 3.96Å; F30-W103 HydrophobicContact CB-CZ3 4.33Å
31I95.1Very high88Confident4 Ų452.7 Ų52.72%0.02126%0.257CS..EExtended strand (participates in β ladder)trans-131.8120.2176.5-58.9-178.5000107.7N4 E7 T33 I37 A38 Y40N4-I31 HydrophobicContact CB-CG2 4.15Å; N4-I31 WeakPolarHBondContact OD1-CG2 3.47Å; E7-I31 HydrophobicContact CB-CG1 4.12Å; I31-T33 HydrophobicContact CG2-CG2 4.28Å; I31-I37 WeakPolarHBondContact O-CA 3.35Å; I31-A38 PolarHBondContact N-O 3.01Å; I31-A38 PolarHBondContact O-N 3.4Å; I31-Y40 HydrophobicContact CB-CE2 4.31Å; I31-Y40 HydrophobicContact CD1-CD2 4.14Å; I31-Y40 HydrophobicContact CD1-CE2 3.71Å; I31-Y40 HydrophobicContact CG1-CD2 4.37Å; I31-Y40 HydrophobicContact CG1-CE2 4.08Å
32L95.5Very high89.5Confident0 Ų052.9 Ų52.90%025%0.252CS..EExtended strand (participates in β ladder)trans-97.3127.7174.2179.560.5000109.3L5 M6 I37 L58 W103 K106 L107 L110L5-L32 HydrophobicContact CB-CG 4.39Å; L5-L32 WeakPolarHBondContact CB-O 3.37Å; L5-L32 PolarHBondContact N-O 3.23Å; M6-L32 HydrophobicContact CB-CB 4.19Å; M6-L32 HydrophobicContact CB-CD2 4.44Å; M6-L32 HydrophobicContact CG-CD2 4.44Å; M6-L32 PolarHBondContact N-O 3.12Å; M6-L32 PolarHBondContact O-N 2.88Å; M6-L32 HydrophobicContact SD-CD2 4.31Å; L32-I37 HydrophobicContact CD1-CB 4.03Å; L32-L58 HydrophobicContact CD1-CD1 4.28Å; L32-L58 HydrophobicContact CD1-CD2 3.95Å; L32-W103 HydrophobicContact CB-CH2 4.04Å; L32-W103 HydrophobicContact CB-CZ3 3.86Å; L32-K106 HydrophobicContact CD2-CB 4.43Å; L32-K106 HydrophobicContact CD2-CG 3.83Å; L32-L107 HydrophobicContact CD1-CD2 3.67Å; L32-L107 HydrophobicContact CD2-CD2 4.15Å; L32-L107 HydrophobicContact CD2-CG 4.33Å; L32-L110 HydrophobicContact CD1-CD1 3.97Å; L32-L110 HydrophobicContact CD2-CD1 3.87Å; L32-L110 HydrophobicContact CG-CD1 4.06Å
33T93.9Very high90.7Very high26 Ų2648.6 Ų48.616%0.1622%0.224CC..EExtended strand (participates in β ladder)trans-118.1-179.9174.364.20000109.6D3 I31 E35 K36D3-T33 WeakPolarHBondContact O-CA 3.48Å; D3-T33 WeakPolarHBondContact O-CB 3.48Å; I31-T33 HydrophobicContact CG2-CG2 4.28Å; T33-E35 PolarHBondContact O-N 3.4Å; T33-E35 PolarHBondContact OG1-N 2.96Å; T33-K36 PolarHBondContact N-O 3.01Å; T33-K36 PolarHBondContact OG1-N 3.07Å; T33-K36 VanDerWaalsContact OG1-N 3.07Å; T33-K36 PolarHBondContact OG1-O 3.36Å
34Q90.6Very high90.6Very high138 Ų13849.8 Ų49.865%0.64524%0.237SC*.SBendtrans-67.5-20.3174.2-67.9-170.14.400113.6L5 L58L5-Q34 HydrophobicContact CD1-CG 4.04Å; L5-Q34 HydrophobicContact CD2-CG 4.31Å; L5-Q34 HydrophobicContact CG-CG 4.35Å; Q34-L58 WeakPolarHBondContact O-CD1 3.49Å
35E92.2Very high90.1Very high150 Ų15054.4 Ų54.470%0.70126%0.256SS*.SBendtrans-107.3-34.1-174-63178.717400113.1T33 L58T33-E35 PolarHBondContact O-N 3.4Å; T33-E35 PolarHBondContact OG1-N 2.96Å; E35-L58 WeakPolarHBondContact O-CB 3.3Å; E35-L58 PolarHBondContact O-N 3.4Å
36K94.6Very high89.3Confident80 Ų8058.8 Ų58.835%0.34828%0.277SS..EExtended strand (participates in β ladder)trans-153.7160.2-172.865.4-170.7175.6-1660113.6T33 A55 V56T33-K36 PolarHBondContact N-O 3.01Å; T33-K36 PolarHBondContact OG1-N 3.07Å; T33-K36 VanDerWaalsContact OG1-N 3.07Å; T33-K36 PolarHBondContact OG1-O 3.36Å; K36-A55 HydrophobicContact CD-CB 4.17Å; K36-V56 WeakPolarHBondContact CA-O 3.29Å; K36-V56 WeakPolarHBondContact CB-O 3.41Å
37I95.6Very high88.6Confident1 Ų156.1 Ų56.11%0.00528%0.278CS..EExtended strand (participates in β ladder)trans-103.9117.6163.2-174.6174.5000109.3F30 I31 L32 A55 V56 I61 I83 W103 L107F30-I37 HydrophobicContact CD1-CD1 3.87Å; F30-I37 HydrophobicContact CD1-CG1 4.02Å; F30-I37 HydrophobicContact CE1-CD1 4.49Å; I31-I37 WeakPolarHBondContact O-CA 3.35Å; L32-I37 HydrophobicContact CD1-CB 4.03Å; I37-A55 CarbonylContact O-C 3.6Å; I37-A55 VanDerWaalsContact O-CA 3.26Å; I37-A55 WeakPolarHBondContact O-CA 3.39Å; I37-V56 HydrophobicContact CG2-CB 3.81Å; I37-V56 PolarHBondContact N-O 3.5Å; I37-V56 PolarHBondContact O-N 3.38Å; I37-I61 HydrophobicContact CG2-CD1 4.46Å; I37-I83 HydrophobicContact CD1-CD1 3.81Å; I37-I83 HydrophobicContact CG2-CD1 4.27Å; I37-W103 HydrophobicContact CD1-CE3 4.3Å; I37-W103 HydrophobicContact CD1-CZ3 3.74Å; I37-W103 HydrophobicContact CG1-CZ3 4.37Å; I37-L107 HydrophobicContact CD1-CD1 4.4Å; I37-L107 HydrophobicContact CD1-CD2 4.37Å
38A94.9Very high87.9Confident4 Ų459.6 Ų59.63%0.03329%0.292CS..EExtended strand (participates in β ladder)trans-111148.2-179.700000110.8F30 I31 Y40 L52 G54 A55F30-A38 CarbonylContact C-O 3.45Å; F30-A38 WeakPolarHBondContact CA-O 3.38Å; I31-A38 PolarHBondContact N-O 3.01Å; I31-A38 PolarHBondContact O-N 3.4Å; A38-Y40 HydrophobicContact CB-CE2 3.88Å; A38-L52 HydrophobicContact CB-CD1 3.89Å; A38-G54 WeakPolarHBondContact CA-O 3.47Å; A38-A55 HydrophobicContact CB-CB 4.03Å
39Y94.5Very high87.4Confident22 Ų2264.1 Ų64.19%0.08631%0.309CS..EExtended strand (participates in β ladder)trans-132.2137.6175.558.1-90.7000112.2K12 R28 W29 F30 K53 G54 L90K12-Y39 HydrophobicContact CD-CD2 3.87Å; K12-Y39 HydrophobicContact CD-CE1 4.38Å; K12-Y39 HydrophobicContact CD-CE2 3.63Å; K12-Y39 HydrophobicContact CD-CG 4.35Å; K12-Y39 WeakPolarHBondContact CE-OH 3.21Å; K12-Y39 PolarHBondContact NZ-OH 3.25Å; R28-Y39 HydrophobicContact CG-CD2 4.37Å; W29-Y39 CarbonylContact O-C 3.55Å; W29-Y39 VanDerWaalsContact O-CA 3.29Å; W29-Y39 WeakPolarHBondContact O-CA 3.37Å; F30-Y39 HydrophobicContact CD1-CD1 4.39Å; F30-Y39 HydrophobicContact CD1-CG 4.43Å; F30-Y39 AromaticContact CE1-CD1 3.76Å; F30-Y39 HydrophobicContact CE1-CD1 3.76Å; F30-Y39 AromaticContact CE1-CG 3.91Å; F30-Y39 HydrophobicContact CE1-CG 3.91Å; F30-Y39 HydrophobicContact CZ-CD1 4.22Å; F30-Y39 HydrophobicContact CZ-CG 4.04Å; Y39-K53 HydrophobicContact CD2-CB 3.77Å; Y39-K53 HydrophobicContact CE2-CB 3.72Å; Y39-K53 PolarHBondContact O-N 2.92Å; Y39-G54 WeakPolarHBondContact CD1-O 3.06Å; Y39-G54 PolarHBondContact N-O 3.18Å; Y39-G54 PolarHBondContact O-N 2.87Å; Y39-L90 HydrophobicContact CE1-CD2 4.48Å
40Y92.9Very high86.9Confident48 Ų4867.2 Ų67.219%0.18832%0.324CS..EExtended strand (participates in β ladder)trans-118.7156-172.7-58.5-102.1000110R28 W29 I31 A38 F42 R49 G51 L52R28-Y40 WeakPolarHBondContact CA-O 3.4Å; R28-Y40 WeakPolarHBondContact CB-O 3.17Å; R28-Y40 WeakPolarHBondContact CD-O 3.26Å; W29-Y40 PolarHBondContact N-O 3.4Å; W29-Y40 WeakPolarHBondContact O-CD2 3.19Å; W29-Y40 PolarHBondContact O-N 3.14Å; I31-Y40 HydrophobicContact CB-CE2 4.31Å; I31-Y40 HydrophobicContact CD1-CD2 4.14Å; I31-Y40 HydrophobicContact CD1-CE2 3.71Å; I31-Y40 HydrophobicContact CG1-CD2 4.37Å; I31-Y40 HydrophobicContact CG1-CE2 4.08Å; A38-Y40 HydrophobicContact CB-CE2 3.88Å; Y40-F42 PolarHBondContact O-N 2.84Å; Y40-R49 HydrophobicContact CD1-CG 4.02Å; Y40-R49 HydrophobicContact CD2-CG 4.33Å; Y40-R49 HydrophobicContact CG-CG 3.72Å; Y40-G51 WeakPolarHBondContact CA-O 3.42Å; Y40-L52 HydrophobicContact CD1-CB 3.93Å; Y40-L52 HydrophobicContact CD1-CD1 4.08Å; Y40-L52 HydrophobicContact CD2-CD1 4.45Å; Y40-L52 HydrophobicContact CE1-CB 3.78Å; Y40-L52 HydrophobicContact CE1-CD1 3.67Å; Y40-L52 HydrophobicContact CE1-CG 4.3Å; Y40-L52 HydrophobicContact CE2-CD1 4.06Å; Y40-L52 HydrophobicContact CG-CD1 4.44Å
41D87.9Confident86.4Confident28 Ų2869.3 Ų69.315%0.1535%0.346CS..EExtended strand (participates in β ladder)trans-60.1137.6165.9-82-27.5000110R28 K50 G51 K53R28-D41 IonicContact CZ-OD1 2.75Å; R28-D41 IonicContact NE-OD1 2.73Å; R28-D41 PolarHBondContact NE-OD1 3.26Å; R28-D41 IonicContact NH1-OD1 3.59Å; R28-D41 PolarHBondContact NH1-OD1 2.73Å; R28-D41 IonicContact NH2-OD1 2.69Å; R28-D41 PolarHBondContact NH2-OD1 3.45Å; D41-K50 HydrophobicContact CB-CB 3.72Å; D41-K50 PolarHBondContact O-N 2.77Å; D41-G51 PolarHBondContact N-O 3.42Å; D41-K53 HydrophobicContact CB-CG 4.46Å; D41-K53 VanDerWaalsContact OD1-CE 3.22Å; D41-K53 WeakPolarHBondContact OD1-CE 3.39Å; D41-K53 VanDerWaalsContact OD1-CG 3.27Å; D41-K53 WeakPolarHBondContact OD1-CG 3.37Å; D41-K53 IonicContact OD1-NZ 2.71Å; D41-K53 WeakPolarHBondContact OD2-CE 3.32Å; D41-K53 IonicContact OD2-NZ 2.66Å; D41-K53 PolarHBondContact OD2-NZ 3.36Å
42F84.8Confident86.2Confident41 Ų4173.8 Ų73.818%0.1837%0.369CS..EExtended strand (participates in β ladder)trans-113.2130176.3178.6-119.3000109.1I9 E27 W29 Y40I9-F42 HydrophobicContact CD1-CD1 4.3Å; I9-F42 HydrophobicContact CD1-CD2 4.15Å; I9-F42 HydrophobicContact CD1-CE1 3.78Å; I9-F42 HydrophobicContact CD1-CE2 3.6Å; I9-F42 HydrophobicContact CD1-CG 4.47Å; I9-F42 HydrophobicContact CD1-CZ 3.4Å; I9-F42 HydrophobicContact CG1-CD2 4.4Å; I9-F42 HydrophobicContact CG1-CE1 4.49Å; I9-F42 HydrophobicContact CG1-CE2 4.32Å; I9-F42 HydrophobicContact CG1-CG 4.5Å; I9-F42 HydrophobicContact CG1-CZ 4.37Å; I9-F42 HydrophobicContact CG2-CD1 3.94Å; I9-F42 HydrophobicContact CG2-CE1 4.18Å; I9-F42 HydrophobicContact CG2-CG 4.42Å; E27-F42 HydrophobicContact CB-CD1 4.26Å; W29-F42 AromaticContact CE3-CD2 3.71Å; W29-F42 HydrophobicContact CE3-CD2 3.71Å; W29-F42 AromaticContact CE3-CE2 3.92Å; W29-F42 HydrophobicContact CE3-CE2 3.92Å; W29-F42 HydrophobicContact CZ3-CD2 4.27Å; W29-F42 HydrophobicContact CZ3-CE2 4.04Å; Y40-F42 PolarHBondContact O-N 2.84Å
43D78.9Confident86Confident19 Ų1979.1 Ų79.110%0.10239%0.392CS..EExtended strand (participates in β ladder)trans-98.2105.9171.7-170.6-38.3000108.4E45 K46 G47 K48 K50D43-E45 VanDerWaalsContact C-N 3.31Å; D43-E45 PolarHBondContact OD1-N 3.33Å; D43-E45 VanDerWaalsContact OD1-N 3.11Å; D43-K46 HydrophobicContact CB-CB 4.35Å; D43-K46 PolarHBondContact OD1-N 3.04Å; D43-G47 WeakPolarHBondContact O-CA 3.42Å; D43-G47 PolarHBondContact O-N 3.25Å; D43-K48 PolarHBondContact N-O 2.85Å; D43-K48 VanDerWaalsContact N-O 3.16Å; D43-K48 PolarHBondContact O-N 2.95Å; D43-K50 HydrophobicContact CB-CD 4.23Å; D43-K50 WeakPolarHBondContact OD2-CE 3.39Å; D43-K50 IonicContact OD2-NZ 2.65Å; D43-K50 PolarHBondContact OD2-NZ 2.81Å
44S73.1Confident85.8Confident86 Ų8678.7 Ų78.760%0.60139%0.393SS*.THydrogen-bonded Turntrans-69.4-27.8-177.951.90000112.8
45E72.3Confident86Confident176 Ų17674.2 Ų74.282%0.82238%0.379SS*.THydrogen-bonded Turntrans-76.7-37178.8-63-172.9165.100111.9D43D43-E45 VanDerWaalsContact C-N 3.31Å; D43-E45 PolarHBondContact OD1-N 3.33Å; D43-E45 VanDerWaalsContact OD1-N 3.11Å
46K72.5Confident86.1Confident151 Ų15167.2 Ų67.266%0.65735%0.347SS*.THydrogen-bonded Turntrans-100.9-8-176.9-63.1-178.2-178.7175.10114.1D43 K48D43-K46 HydrophobicContact CB-CB 4.35Å; D43-K46 PolarHBondContact OD1-N 3.04Å; K46-K48 PolarHBondContact O-N 2.83Å
47G73.9Confident86Confident46 Ų4666 Ų6647%0.47434%0.344SS..THydrogen-bonded Turntrans61.426.4-177.700000114D43D43-G47 WeakPolarHBondContact O-CA 3.42Å; D43-G47 PolarHBondContact O-N 3.25Å
48K79.6Confident85.9Confident147 Ų14766.3 Ų66.364%0.63935%0.346SS*.EExtended strand (participates in β ladder)trans-118.3142.5-171.6-75.9-178.9-176.4-176.90113D43 K46D43-K48 PolarHBondContact N-O 2.85Å; D43-K48 VanDerWaalsContact N-O 3.16Å; D43-K48 PolarHBondContact O-N 2.95Å; K46-K48 PolarHBondContact O-N 2.83Å
49R81.9Confident85.8Confident127 Ų12772.9 Ų72.948%0.47938%0.376SS..EExtended strand (participates in β ladder)trans-71.4128.6169.8-171-179.671.1-171.60.7110.2W29 Y40W29-R49 HydrophobicContact CB-CG 4.49Å; W29-R49 HydrophobicContact CD2-CB 4.39Å; W29-R49 HydrophobicContact CE3-CB 4.22Å; W29-R49 HydrophobicContact CG-CG 4.47Å; Y40-R49 HydrophobicContact CD1-CG 4.02Å; Y40-R49 HydrophobicContact CD2-CG 4.33Å; Y40-R49 HydrophobicContact CG-CG 3.72Å
50K83.7Confident85.7Confident117 Ų11775.8 Ų75.851%0.50939%0.389SS..EExtended strand (participates in β ladder)trans-104-149.2175.7-73-178.7173.3166.40110.6D41 D43D41-K50 HydrophobicContact CB-CB 3.72Å; D41-K50 PolarHBondContact O-N 2.77Å; D43-K50 HydrophobicContact CB-CD 4.23Å; D43-K50 WeakPolarHBondContact OD2-CE 3.39Å; D43-K50 IonicContact OD2-NZ 2.65Å; D43-K50 PolarHBondContact OD2-NZ 2.81Å
51G86.3Confident85.7Confident45 Ų4573.6 Ų73.646%0.46438%0.381SS..EExtended strand (participates in β ladder)trans-64.4150-176.700000114.2Y40 D41 K53Y40-G51 WeakPolarHBondContact CA-O 3.42Å; D41-G51 PolarHBondContact N-O 3.42Å; G51-K53 PolarHBondContact O-N 2.9Å
52L91Very high85.9Confident97 Ų9774.9 Ų74.951%0.50839%0.385SS..EExtended strand (participates in β ladder)trans-63.9126.6173.217967.5000109.6A38 Y40A38-L52 HydrophobicContact CB-CD1 3.89Å; Y40-L52 HydrophobicContact CD1-CB 3.93Å; Y40-L52 HydrophobicContact CD1-CD1 4.08Å; Y40-L52 HydrophobicContact CD2-CD1 4.45Å; Y40-L52 HydrophobicContact CE1-CB 3.78Å; Y40-L52 HydrophobicContact CE1-CD1 3.67Å; Y40-L52 HydrophobicContact CE1-CG 4.3Å; Y40-L52 HydrophobicContact CE2-CD1 4.06Å; Y40-L52 HydrophobicContact CG-CD1 4.44Å
53K90.3Very high86.3Confident113 Ų11373 Ų7349%0.49138%0.377SS..EExtended strand (participates in β ladder)trans-102.4-25.7178.6-75.2-48.8-147.1-130.70113.8Y39 D41 G51Y39-K53 HydrophobicContact CD2-CB 3.77Å; Y39-K53 HydrophobicContact CE2-CB 3.72Å; Y39-K53 PolarHBondContact O-N 2.92Å; D41-K53 HydrophobicContact CB-CG 4.46Å; D41-K53 VanDerWaalsContact OD1-CE 3.22Å; D41-K53 WeakPolarHBondContact OD1-CE 3.39Å; D41-K53 VanDerWaalsContact OD1-CG 3.27Å; D41-K53 WeakPolarHBondContact OD1-CG 3.37Å; D41-K53 IonicContact OD1-NZ 2.71Å; D41-K53 WeakPolarHBondContact OD2-CE 3.32Å; D41-K53 IonicContact OD2-NZ 2.66Å; D41-K53 PolarHBondContact OD2-NZ 3.36Å; G51-K53 PolarHBondContact O-N 2.9Å
54G90.8Very high87.1Confident17 Ų1772.4 Ų72.418%0.17537%0.374CS..EExtended strand (participates in β ladder)trans178.9167.3172.900000111.8A38 Y39A38-G54 WeakPolarHBondContact CA-O 3.47Å; Y39-G54 WeakPolarHBondContact CD1-O 3.06Å; Y39-G54 PolarHBondContact N-O 3.18Å; Y39-G54 PolarHBondContact O-N 2.87Å
55A93.7Very high88.1Confident43 Ų4369.5 Ų69.536%0.35535%0.351SS..EExtended strand (participates in β ladder)trans-145.4151174.900000109.9K36 I37 A38K36-A55 HydrophobicContact CD-CB 4.17Å; I37-A55 CarbonylContact O-C 3.6Å; I37-A55 VanDerWaalsContact O-CA 3.26Å; I37-A55 WeakPolarHBondContact O-CA 3.39Å; A38-A55 HydrophobicContact CB-CB 4.03Å
56V93.9Very high89.2Confident4 Ų463.6 Ų63.62%0.02433%0.327CS..EExtended strand (participates in β ladder)trans-122117.9172.6-176.90000107.3K36 I37 I61 Y85 L90K36-V56 WeakPolarHBondContact CA-O 3.29Å; K36-V56 WeakPolarHBondContact CB-O 3.41Å; I37-V56 HydrophobicContact CG2-CB 3.81Å; I37-V56 PolarHBondContact N-O 3.5Å; I37-V56 PolarHBondContact O-N 3.38Å; V56-I61 HydrophobicContact CG1-CD1 4.25Å; V56-I61 HydrophobicContact CG1-CG1 3.73Å; V56-Y85 HydrophobicContact CG1-CD1 4.01Å; V56-Y85 HydrophobicContact CG1-CD2 4.03Å; V56-Y85 HydrophobicContact CG1-CG 3.71Å; V56-Y85 HydrophobicContact CG2-CD1 4.09Å; V56-Y85 HydrophobicContact CG2-CE1 3.87Å; V56-Y85 HydrophobicContact CG2-CE2 4.3Å; V56-Y85 HydrophobicContact CG2-CG 4.42Å; V56-L90 HydrophobicContact CG2-CD2 4.15Å
57D94.3Very high90.2Very high53 Ų5356.5 Ų56.528%0.28330%0.296SS..EExtended strand (participates in β ladder)trans-66.6133.5175-54-38.7000109E59 K60D57-E59 HydrophobicContact CB-CG 4.11Å; D57-E59 PolarHBondContact O-N 3.33Å; D57-K60 HydrophobicContact CB-CD 4.23Å; D57-K60 HydrophobicContact CB-CG 4.31Å; D57-K60 PolarHBondContact O-N 3.24Å; D57-K60 IonicContact OD2-NZ 2.71Å; D57-K60 PolarHBondContact OD2-NZ 3.33Å
58L92.6Very high91Very high9 Ų959.4 Ų59.45%0.04730%0.297CS..G310 helixtrans-62.6-31.8-173.7-67.3-175.5000111.8L32 Q34 E35 K60 I61 L107 L110 V111 N114L32-L58 HydrophobicContact CD1-CD1 4.28Å; L32-L58 HydrophobicContact CD1-CD2 3.95Å; Q34-L58 WeakPolarHBondContact O-CD1 3.49Å; E35-L58 WeakPolarHBondContact O-CB 3.3Å; E35-L58 PolarHBondContact O-N 3.4Å; L58-K60 PolarHBondContact O-N 3.15Å; L58-I61 HydrophobicContact CD2-CD1 3.55Å; L58-I61 WeakPolarHBondContact O-CB 3.29Å; L58-I61 PolarHBondContact O-N 2.9Å; L58-L107 HydrophobicContact CD2-CD2 4.06Å; L58-L110 HydrophobicContact CD1-CB 3.9Å; L58-L110 HydrophobicContact CD1-CD1 3.75Å; L58-L110 HydrophobicContact CD1-CG 4.33Å; L58-V111 HydrophobicContact CB-CG1 4.38Å; L58-V111 HydrophobicContact CD2-CG1 4.42Å; L58-N114 PolarHBondContact O-ND2 2.76Å
59E92.1Very high91.2Very high141 Ų14155.5 Ų55.566%0.65929%0.287SS*.G310 helixtrans-62.1-27.3176.266.6180-17500113.5D57 N114D57-E59 HydrophobicContact CB-CG 4.11Å; D57-E59 PolarHBondContact O-N 3.33Å; E59-N114 PolarHBondContact O-ND2 2.84Å
60K92.4Very high91Very high83 Ų8352 Ų5236%0.36128%0.276SS..G310 helixtrans-87.3-8.2-178.8-63.4178.8-177.5150.90113D57 L58 K62 Y85D57-K60 HydrophobicContact CB-CD 4.23Å; D57-K60 HydrophobicContact CB-CG 4.31Å; D57-K60 PolarHBondContact O-N 3.24Å; D57-K60 IonicContact OD2-NZ 2.71Å; D57-K60 PolarHBondContact OD2-NZ 3.33Å; L58-K60 PolarHBondContact O-N 3.15Å; K60-K62 PolarHBondContact O-N 2.87Å; K60-Y85 WeakPolarHBondContact O-CA 3.31Å; K60-Y85 WeakPolarHBondContact O-CB 3.31Å
61I94.3Very high90.4Very high2 Ų252.7 Ų52.71%0.0129%0.293CS..  trans-74.5123.3-179.8-62.9178.4000109.3I37 V56 L58 V64 I83 V111 N114I37-I61 HydrophobicContact CG2-CD1 4.46Å; V56-I61 HydrophobicContact CG1-CD1 4.25Å; V56-I61 HydrophobicContact CG1-CG1 3.73Å; L58-I61 HydrophobicContact CD2-CD1 3.55Å; L58-I61 WeakPolarHBondContact O-CB 3.29Å; L58-I61 PolarHBondContact O-N 2.9Å; I61-V64 HydrophobicContact CG2-CG2 3.57Å; I61-I83 HydrophobicContact CB-CG2 4.44Å; I61-I83 HydrophobicContact CD1-CG2 3.72Å; I61-I83 HydrophobicContact CG1-CG2 3.78Å; I61-I83 HydrophobicContact CG2-CG2 3.89Å; I61-V111 HydrophobicContact CB-CG1 3.83Å; I61-V111 HydrophobicContact CD1-CG1 4.01Å; I61-V111 HydrophobicContact CG1-CG1 4.44Å; I61-V111 HydrophobicContact CG2-CB 4.45Å; I61-V111 HydrophobicContact CG2-CG1 3.99Å; I61-V111 HydrophobicContact CG2-CG2 4.34Å; I61-N114 PolarHBondContact O-ND2 2.94Å
62K92.6Very high89.9Confident56 Ų5658.1 Ų58.124%0.24331%0.311CS..  trans-101.8-23.4-178.6-52.7-173.1179171.80113K60 I84 D86 D116 L117 M118K60-K62 PolarHBondContact O-N 2.87Å; K62-I84 PolarHBondContact N-O 2.84Å; K62-D86 WeakPolarHBondContact CE-OD1 3.5Å; K62-D86 IonicContact NZ-OD1 2.63Å; K62-D86 PolarHBondContact NZ-OD1 2.75Å; K62-D116 WeakPolarHBondContact CB-O 2.93Å; K62-D116 WeakPolarHBondContact CG-O 3.42Å; K62-L117 WeakPolarHBondContact O-CA 3.48Å; K62-M118 HydrophobicContact CB-CG 3.76Å; K62-M118 HydrophobicContact CB-SD 4.39Å; K62-M118 PolarHBondContact O-N 2.83Å
63C92.5Very high89.2Confident2 Ų254.3 Ų54.31%0.01429%0.294CS..EExtended strand (participates in β ladder)trans-160.6143.9175.9179.30000111.4I84 M118C63-I84 HydrophobicContact CB-CB 4.11Å; C63-I84 HydrophobicContact CB-CD1 4.12Å; C63-I84 HydrophobicContact CB-CG1 4.34Å; C63-I84 PolarHBondContact N-O 2.72Å; C63-I84 PolarHBondContact O-N 3.14Å; C63-M118 HydrophobicContact CB-CE 3.41Å; C63-M118 VanDerWaalsContact CB-CE 3.41Å
64V94.9Very high88.9Confident5 Ų551.2 Ų51.23%0.0329%0.285CS..EExtended strand (participates in β ladder)trans-131115.6168.2-176.30000108.3I61 F81 Q82 I83 I104 L107 K108 V111I61-V64 HydrophobicContact CG2-CG2 3.57Å; V64-F81 HydrophobicContact CG1-CD2 4.48Å; V64-Q82 WeakPolarHBondContact CA-O 3.41Å; V64-I83 HydrophobicContact CG1-CG1 4.42Å; V64-I83 HydrophobicContact CG2-CG1 4.33Å; V64-I83 HydrophobicContact CG2-CG2 4.39Å; V64-I104 HydrophobicContact CG1-CG1 4.37Å; V64-I104 HydrophobicContact CG1-CG2 4.37Å; V64-L107 HydrophobicContact CB-CB 4.48Å; V64-L107 HydrophobicContact CG1-CB 4.04Å; V64-L107 HydrophobicContact CG1-CD1 4.08Å; V64-L107 HydrophobicContact CG2-CB 4.14Å; V64-K108 HydrophobicContact CB-CG 4.32Å; V64-K108 WeakPolarHBondContact O-CE 3.49Å; V64-V111 HydrophobicContact CG2-CG2 4.48Å
65E95Very high88.3Confident25 Ų2558.4 Ų58.412%0.11731%0.314CS..EExtended strand (participates in β ladder)trans-148.7163.5-177.4-95.8-59.6172.700113.5F81 Q82 K108 Y121 L147E65-F81 CarbonylContact O-C 3.45Å; E65-F81 WeakPolarHBondContact O-CA 3.34Å; E65-F81 WeakPolarHBondContact O-CB 3.44Å; E65-Q82 PolarHBondContact N-O 3Å; E65-Q82 VanDerWaalsContact N-O 3.13Å; E65-Q82 PolarHBondContact O-N 2.86Å; E65-K108 VanDerWaalsContact CD-NZ 3.27Å; E65-K108 IonicContact OE1-NZ 3.7Å; E65-K108 PolarHBondContact OE1-NZ 3.49Å; E65-K108 IonicContact OE2-NZ 2.95Å; E65-Y121 HydrophobicContact CB-CD2 3.9Å; E65-Y121 HydrophobicContact CB-CE2 3.65Å; E65-Y121 HydrophobicContact CB-CG 4.49Å; E65-Y121 HydrophobicContact CG-CD1 4.27Å; E65-Y121 HydrophobicContact CG-CD2 4.17Å; E65-Y121 HydrophobicContact CG-CE1 3.92Å; E65-Y121 HydrophobicContact CG-CE2 3.81Å; E65-Y121 HydrophobicContact CG-CG 4.38Å; E65-L147 HydrophobicContact CG-CD1 3.82Å
66T94.4Very high87.8Confident52 Ų5262.1 Ų62.132%0.31932%0.324SS..EExtended strand (participates in β ladder)trans-64.8149.6169.954.80000111.7I104T66-I104 HydrophobicContact CG2-CD1 3.54Å
67V93.5Very high87.5Confident2 Ų264.8 Ų64.81%0.01233%0.333CS..  trans-115.1135.7172.8-175.70000108.5A80 Q82 Y91 P123 F125V67-A80 HydrophobicContact CB-CB 4.01Å; V67-A80 PolarHBondContact N-O 3.07Å; V67-Q82 HydrophobicContact CG2-CB 3.61Å; V67-Q82 HydrophobicContact CG2-CG 3.7Å; V67-Y91 HydrophobicContact CG1-CE1 4.46Å; V67-Y91 HydrophobicContact CG2-CD1 3.98Å; V67-Y91 HydrophobicContact CG2-CE1 4.08Å; V67-P123 CarbonylContact C-O 3.58Å; V67-P123 WeakPolarHBondContact CA-O 3.4Å; V67-F125 HydrophobicContact CB-CE1 4.45Å; V67-F125 HydrophobicContact CB-CZ 4.33Å; V67-F125 HydrophobicContact CG1-CD1 3.93Å; V67-F125 HydrophobicContact CG1-CD2 4.03Å; V67-F125 HydrophobicContact CG1-CE1 3.7Å; V67-F125 HydrophobicContact CG1-CE2 3.77Å; V67-F125 HydrophobicContact CG1-CG 4.1Å; V67-F125 HydrophobicContact CG1-CZ 3.61Å
68Q90.4Very high87.2Confident107 Ų10765.8 Ų65.850%0.534%0.337SS..PPolyproline II helixtrans-64.1131.4176.8-68.3-177.1-2.800109.8P123 C124 F125Q68-P123 HydrophobicContact CG-CB 4.37Å; Q68-P123 PolarHBondContact N-O 3.41Å; Q68-C124 PolarHBondContact OE1-SG 2.88Å; Q68-F125 WeakPolarHBondContact O-CE2 3.32Å
69P83.7Confident87.2Confident65 Ų6569.1 Ų69.142%0.42235%0.35SS..PPolyproline II helixtrans-66.7150.8179.527.8-33.4000110.9M78P69-M78 HydrophobicContact CB-SD 4.47Å
70E79.4Confident87.3Confident54 Ų5462.4 Ų62.425%0.25232%0.318SS..PPolyproline II helixtrans-69.1147.3173.8-58.9175.1108.100109.8N72 A73 R77 F125E70-N72 PolarHBondContact O-N 2.74Å; E70-A73 HydrophobicContact CB-CB 4.25Å; E70-A73 PolarHBondContact O-N 3.05Å; E70-A73 VanDerWaalsContact O-N 3.11Å; E70-R77 IonicContact OE2-NH1 3.18Å; E70-F125 HydrophobicContact CG-CD2 3.79Å; E70-F125 HydrophobicContact CG-CE2 3.75Å
71P70.5Confident87.5Confident132 Ų13258.4 Ų58.486%0.85730%0.301SS*.THydrogen-bonded Turntrans-56.8-17.1-173.4-25.833.6000115.8
72N75.4Confident87.5Confident159 Ų15958.3 Ų58.385%0.8530%0.301SS*.THydrogen-bonded Turntrans-136.532.7179.8-66.3-37.4000112.4E70E70-N72 PolarHBondContact O-N 2.74Å
73A77.4Confident87.6Confident17 Ų1755.7 Ų55.714%0.1429%0.289CS..  trans-65136.4179.300000111.2E70 R77 M78E70-A73 HydrophobicContact CB-CB 4.25Å; E70-A73 PolarHBondContact O-N 3.05Å; E70-A73 VanDerWaalsContact O-N 3.11Å; A73-R77 HydrophobicContact CB-CB 4.19Å; A73-M78 HydrophobicContact CB-SD 4.12Å
74P82.5Confident87.6Confident47 Ų4756.4 Ų56.431%0.30529%0.293SS..  trans-62.1157.5170.327.7-34000110.4E76 R77P74-E76 HydrophobicContact CB-CG 4.11Å; P74-E76 HydrophobicContact CG-CG 4.11Å; P74-E76 PolarHBondContact O-N 3.08Å; P74-E76 VanDerWaalsContact O-N 3.09Å; P74-R77 VanDerWaalsContact CD-CZ 3.43Å; P74-R77 VanDerWaalsContact CD-NH2 3.27Å; P74-R77 HydrophobicContact CG-CB 4.26Å; P74-R77 HydrophobicContact CG-CG 4.26Å; P74-R77 VanDerWaalsContact CG-NH2 3.31Å; P74-R77 WeakPolarHBondContact O-CA 3.21Å; P74-R77 PolarHBondContact O-N 2.9Å
75Q79.6Confident87.4Confident169 Ų16957 Ų5779%0.7930%0.295SS*.G310 helixtrans-53.7-37-171.5-170.2171.1-0.200113.5R77 M78Q75-R77 PolarHBondContact O-N 2.86Å; Q75-M78 WeakPolarHBondContact O-CB 3.38Å; Q75-M78 WeakPolarHBondContact O-CG 3.27Å; Q75-M78 PolarHBondContact O-N 3.11Å
76E82.1Confident86.8Confident120 Ų12059.3 Ų59.356%0.56131%0.307SS*.G310 helixtrans-65.1-15175.553.4175.7-161.700115.1I11 P74I11-E76 HydrophobicContact CD1-CB 4.09Å; P74-E76 HydrophobicContact CB-CG 4.11Å; P74-E76 HydrophobicContact CG-CG 4.11Å; P74-E76 PolarHBondContact O-N 3.08Å; P74-E76 VanDerWaalsContact O-N 3.09Å
77R87.9Confident86.2Confident60 Ų6062.4 Ų62.423%0.22632%0.319CS..G310 helixtrans-111.39.9179.9-71.5-169.6-82153.6-9.8113.6E70 A73 P74 Q75 F93E70-R77 IonicContact OE2-NH1 3.18Å; A73-R77 HydrophobicContact CB-CB 4.19Å; P74-R77 VanDerWaalsContact CD-CZ 3.43Å; P74-R77 VanDerWaalsContact CD-NH2 3.27Å; P74-R77 HydrophobicContact CG-CB 4.26Å; P74-R77 HydrophobicContact CG-CG 4.26Å; P74-R77 VanDerWaalsContact CG-NH2 3.31Å; P74-R77 WeakPolarHBondContact O-CA 3.21Å; P74-R77 PolarHBondContact O-N 2.9Å; Q75-R77 PolarHBondContact O-N 2.86Å; R77-F93 HydrophobicContact CB-CD1 3.85Å; R77-F93 HydrophobicContact CB-CE1 3.98Å; R77-F93 HydrophobicContact CG-CD1 4.05Å; R77-F93 HydrophobicContact CG-CE1 4.19Å; R77-F93 HydrophobicContact CG-CG 4.36Å; R77-F93 WeakPolarHBondContact O-CD1 3.3Å
78M87.2Confident85.9Confident74 Ų7462.6 Ų62.637%0.36532%0.32SS..SBendtrans-73-31.3-177.8-69.4-62.2-67.500113.5P69 A73 Q75 A80P69-M78 HydrophobicContact CB-SD 4.47Å; A73-M78 HydrophobicContact CB-SD 4.12Å; Q75-M78 WeakPolarHBondContact O-CB 3.38Å; Q75-M78 WeakPolarHBondContact O-CG 3.27Å; Q75-M78 PolarHBondContact O-N 3.11Å; M78-A80 PolarHBondContact O-N 3.15Å
79Y92.7Very high85.9Confident79 Ų7957.7 Ų57.731%0.3130%0.298SS..EExtended strand (participates in β ladder)trans-104.965.4-174-49.2-68.6000111.7F93 A94 K95 D97Y79-F93 WeakPolarHBondContact O-CA 3.33Å; Y79-A94 PolarHBondContact O-N 2.75Å; Y79-K95 WeakPolarHBondContact CD2-O 3.44Å; Y79-D97 HydrophobicContact CD1-CB 3.69Å; Y79-D97 HydrophobicContact CE1-CB 3.66Å
80A94.6Very high86.4Confident0 Ų054.6 Ų54.60%028%0.278CS..EExtended strand (participates in β ladder)trans-82.9144178.400000113V67 M78 I92 F93 R100 F125V67-A80 HydrophobicContact CB-CB 4.01Å; V67-A80 PolarHBondContact N-O 3.07Å; M78-A80 PolarHBondContact O-N 3.15Å; A80-I92 CarbonylContact C-O 3.53Å; A80-I92 WeakPolarHBondContact CA-O 3.27Å; A80-F93 HydrophobicContact CB-CD1 3.57Å; A80-F93 HydrophobicContact CB-CE1 3.54Å; A80-F93 HydrophobicContact CB-CG 4.49Å; A80-F93 HydrophobicContact CB-CZ 4.43Å; A80-R100 WeakPolarHBondContact O-CD 3.42Å; A80-R100 PolarHBondContact O-NH1 2.57Å; A80-R100 VanDerWaalsContact O-NH1 3.16Å; A80-F125 HydrophobicContact CB-CE1 4.47Å; A80-F125 HydrophobicContact CB-CZ 3.85Å
81F96.2Very high87.1Confident0 Ų052.2 Ų52.20%027%0.267CS..EExtended strand (participates in β ladder)trans-142163.7165.472.8-81.8000110.5F10 V64 E65 I83 I92 R100 W103 I104 L107F10-F81 HydrophobicContact CE2-CZ 4.44Å; F10-F81 HydrophobicContact CZ-CE1 4.44Å; V64-F81 HydrophobicContact CG1-CD2 4.48Å; E65-F81 CarbonylContact O-C 3.45Å; E65-F81 WeakPolarHBondContact O-CA 3.34Å; E65-F81 WeakPolarHBondContact O-CB 3.44Å; F81-I83 HydrophobicContact CE2-CD1 4.32Å; F81-I83 HydrophobicContact CE2-CG1 4.22Å; F81-I92 HydrophobicContact CD1-CB 4.07Å; F81-I92 HydrophobicContact CD1-CG2 4.34Å; F81-I92 WeakPolarHBondContact CD1-O 3.42Å; F81-I92 HydrophobicContact CE1-CB 3.6Å; F81-I92 HydrophobicContact CE1-CG2 3.47Å; F81-I92 VanDerWaalsContact CE1-CG2 3.47Å; F81-I92 HydrophobicContact CE2-CB 4.13Å; F81-I92 HydrophobicContact CE2-CD1 3.86Å; F81-I92 HydrophobicContact CE2-CG1 4.46Å; F81-I92 HydrophobicContact CZ-CB 3.64Å; F81-I92 HydrophobicContact CZ-CD1 3.8Å; F81-I92 HydrophobicContact CZ-CG1 4.28Å; F81-I92 HydrophobicContact CZ-CG2 3.57Å; F81-I92 PolarHBondContact N-O 2.9Å; F81-I92 PolarHBondContact O-N 3.38Å; F81-R100 HydrophobicContact CB-CG 4.19Å; F81-R100 HydrophobicContact CD1-CG 3.99Å; F81-R100 HydrophobicContact CG-CG 4.4Å; F81-W103 HydrophobicContact CZ-CB 4.48Å; F81-I104 HydrophobicContact CB-CD1 3.64Å; F81-I104 HydrophobicContact CB-CG1 3.93Å; F81-I104 HydrophobicContact CD2-CG1 4Å; F81-I104 HydrophobicContact CG-CD1 4.23Å; F81-I104 HydrophobicContact CG-CG1 4.02Å; F81-L107 HydrophobicContact CE2-CD1 4.12Å
82Q95.1Very high88.3Confident0 Ų046 Ų460%023%0.226CC..EExtended strand (participates in β ladder)trans-125.6146.6-178.864.1-171.7-39.500112.1V64 E65 V67 I84 L90 Y91 H122V64-Q82 WeakPolarHBondContact CA-O 3.41Å; E65-Q82 PolarHBondContact N-O 3Å; E65-Q82 VanDerWaalsContact N-O 3.13Å; E65-Q82 PolarHBondContact O-N 2.86Å; V67-Q82 HydrophobicContact CG2-CB 3.61Å; V67-Q82 HydrophobicContact CG2-CG 3.7Å; Q82-I84 HydrophobicContact CG-CD1 4.43Å; Q82-I84 HydrophobicContact CG-CG1 4.26Å; Q82-L90 CarbonylContact C-O 3.55Å; Q82-L90 VanDerWaalsContact CA-O 3.26Å; Q82-L90 WeakPolarHBondContact CA-O 3.29Å; Q82-Y91 HydrophobicContact CB-CD1 3.89Å; Q82-Y91 HydrophobicContact CB-CE1 4.04Å; Q82-H122 PolarHBondContact NE2-O 2.82Å
83I95.1Very high89.3Confident0 Ų038.5 Ų38.50%019%0.186CC..EExtended strand (participates in β ladder)trans-116.5114.8166.1-57176.6000106.8I37 I61 V64 F81 L90 I92 L107I37-I83 HydrophobicContact CD1-CD1 3.81Å; I37-I83 HydrophobicContact CG2-CD1 4.27Å; I61-I83 HydrophobicContact CB-CG2 4.44Å; I61-I83 HydrophobicContact CD1-CG2 3.72Å; I61-I83 HydrophobicContact CG1-CG2 3.78Å; I61-I83 HydrophobicContact CG2-CG2 3.89Å; V64-I83 HydrophobicContact CG1-CG1 4.42Å; V64-I83 HydrophobicContact CG2-CG1 4.33Å; V64-I83 HydrophobicContact CG2-CG2 4.39Å; F81-I83 HydrophobicContact CE2-CD1 4.32Å; F81-I83 HydrophobicContact CE2-CG1 4.22Å; I83-L90 HydrophobicContact CB-CB 4.3Å; I83-L90 PolarHBondContact N-O 3.35Å; I83-L90 WeakPolarHBondContact O-CB 3.39Å; I83-L90 PolarHBondContact O-N 3.25Å; I83-I92 HydrophobicContact CD1-CD1 3.75Å; I83-I92 HydrophobicContact CG1-CD1 4.28Å; I83-L107 HydrophobicContact CD1-CD1 3.75Å; I83-L107 HydrophobicContact CG1-CD1 4.27Å
84I91.9Very high90.1Very high17 Ų1737.8 Ų37.89%0.08718%0.18CC..EExtended strand (participates in β ladder)trans-99.4124.9178.9-54.3176.1000108.1K62 C63 Q82 P89 M118K62-I84 PolarHBondContact N-O 2.84Å; C63-I84 HydrophobicContact CB-CB 4.11Å; C63-I84 HydrophobicContact CB-CD1 4.12Å; C63-I84 HydrophobicContact CB-CG1 4.34Å; C63-I84 PolarHBondContact N-O 2.72Å; C63-I84 PolarHBondContact O-N 3.14Å; Q82-I84 HydrophobicContact CG-CD1 4.43Å; Q82-I84 HydrophobicContact CG-CG1 4.26Å; I84-P89 HydrophobicContact CG1-CB 4.25Å; I84-M118 HydrophobicContact CB-CE 3.84Å; I84-M118 HydrophobicContact CD1-CE 3.4Å; I84-M118 VanDerWaalsContact CD1-CE 3.4Å; I84-M118 HydrophobicContact CG1-CE 4.19Å; I84-M118 HydrophobicContact CG2-CE 3.63Å; I84-M118 HydrophobicContact CG2-SD 4.28Å
85Y91.6Very high90.5Very high19 Ų1941.2 Ų41.28%0.07519%0.19CC..EExtended strand (participates in β ladder)trans-140.1-171.6176.770.3-75.4000109.3Q15 V56 K60 E87 G88 L90Q15-Y85 PolarHBondContact NE2-OH 3.29Å; Q15-Y85 PolarHBondContact OE1-OH 2.81Å; V56-Y85 HydrophobicContact CG1-CD1 4.01Å; V56-Y85 HydrophobicContact CG1-CD2 4.03Å; V56-Y85 HydrophobicContact CG1-CG 3.71Å; V56-Y85 HydrophobicContact CG2-CD1 4.09Å; V56-Y85 HydrophobicContact CG2-CE1 3.87Å; V56-Y85 HydrophobicContact CG2-CE2 4.3Å; V56-Y85 HydrophobicContact CG2-CG 4.42Å; K60-Y85 WeakPolarHBondContact O-CA 3.31Å; K60-Y85 WeakPolarHBondContact O-CB 3.31Å; Y85-E87 VanDerWaalsContact C-N 3.26Å; Y85-E87 HydrophobicContact CD2-CB 4.3Å; Y85-E87 HydrophobicContact CD2-CG 4.35Å; Y85-E87 HydrophobicContact CE2-CB 3.54Å; Y85-E87 HydrophobicContact CE2-CG 3.57Å; Y85-E87 WeakPolarHBondContact CE2-OE2 3.47Å; Y85-E87 PolarHBondContact O-N 3.29Å; Y85-E87 VanDerWaalsContact O-N 3.12Å; Y85-E87 PolarHBondContact OH-OE2 3.25Å; Y85-G88 WeakPolarHBondContact CD1-O 3.28Å; Y85-G88 PolarHBondContact N-O 2.8Å; Y85-G88 PolarHBondContact O-N 2.99Å; Y85-L90 HydrophobicContact CE1-CB 4.13Å
86D82.3Confident91.1Very high72 Ų7235.9 Ų35.939%0.38517%0.169SC..THydrogen-bonded Turntrans-53-35.3-172.3-63.2-41.7000115.3K62 G88 Q140K62-D86 WeakPolarHBondContact CE-OD1 3.5Å; K62-D86 IonicContact NZ-OD1 2.63Å; K62-D86 PolarHBondContact NZ-OD1 2.75Å; D86-G88 VanDerWaalsContact C-N 3.32Å; D86-G88 PolarHBondContact O-N 3.39Å; D86-Q140 PolarHBondContact O-NE2 2.95Å
87E81.5Confident91.6Very high118 Ų11833.5 Ų33.555%0.55116%0.16SC*.THydrogen-bonded Turntrans-86.2-0.8-179.7-55.4-176.4147.900113.8Y85Y85-E87 VanDerWaalsContact C-N 3.26Å; Y85-E87 HydrophobicContact CD2-CB 4.3Å; Y85-E87 HydrophobicContact CD2-CG 4.35Å; Y85-E87 HydrophobicContact CE2-CB 3.54Å; Y85-E87 HydrophobicContact CE2-CG 3.57Å; Y85-E87 WeakPolarHBondContact CE2-OE2 3.47Å; Y85-E87 PolarHBondContact O-N 3.29Å; Y85-E87 VanDerWaalsContact O-N 3.12Å; Y85-E87 PolarHBondContact OH-OE2 3.25Å
88G85.9Confident91.8Very high5 Ų536.8 Ų36.85%0.05218%0.182CC..EExtended strand (participates in β ladder)trans110.1-166.117900000114.5Y85 D86 L90Y85-G88 WeakPolarHBondContact CD1-O 3.28Å; Y85-G88 PolarHBondContact N-O 2.8Å; Y85-G88 PolarHBondContact O-N 2.99Å; D86-G88 VanDerWaalsContact C-N 3.32Å; D86-G88 PolarHBondContact O-N 3.39Å; G88-L90 PolarHBondContact O-N 3.21Å
89P91.1Very high92.2Very high4 Ų435.2 Ų35.23%0.02618%0.175CC..EExtended strand (participates in β ladder)trans-74.3125.7-176.230.2-36.1000112.1I84 Y91 W131I84-P89 HydrophobicContact CG1-CB 4.25Å; P89-Y91 HydrophobicContact CB-CE1 4.01Å; P89-Y91 HydrophobicContact CB-CE2 4.01Å; P89-Y91 HydrophobicContact CG-CE2 3.89Å; P89-Y91 WeakPolarHBondContact CG-OH 3.18Å; P89-W131 HydrophobicContact CB-CH2 4.29Å; P89-W131 HydrophobicContact CG-CH2 3.85Å; P89-W131 HydrophobicContact CG-CZ2 4.46Å
90L93.5Very high92.4Very high0 Ų033.1 Ų33.10%017%0.166CC..EExtended strand (participates in β ladder)trans-93.9111.6164.4171.960.1000109.1K12 Y39 V56 Q82 I83 Y85 G88 I92K12-L90 HydrophobicContact CD-CD1 3.88Å; K12-L90 HydrophobicContact CG-CD1 3.91Å; Y39-L90 HydrophobicContact CE1-CD2 4.48Å; V56-L90 HydrophobicContact CG2-CD2 4.15Å; Q82-L90 CarbonylContact C-O 3.55Å; Q82-L90 VanDerWaalsContact CA-O 3.26Å; Q82-L90 WeakPolarHBondContact CA-O 3.29Å; I83-L90 HydrophobicContact CB-CB 4.3Å; I83-L90 PolarHBondContact N-O 3.35Å; I83-L90 WeakPolarHBondContact O-CB 3.39Å; I83-L90 PolarHBondContact O-N 3.25Å; Y85-L90 HydrophobicContact CE1-CB 4.13Å; G88-L90 PolarHBondContact O-N 3.21Å; L90-I92 HydrophobicContact CD1-CG1 4.47Å; L90-I92 HydrophobicContact CD2-CD1 4.07Å; L90-I92 HydrophobicContact CD2-CG1 4.46Å; L90-I92 HydrophobicContact CG-CD1 4.1Å; L90-I92 HydrophobicContact CG-CG1 3.99Å
91Y95.1Very high92.3Very high5 Ų535.6 Ų35.62%0.0219%0.187CC..EExtended strand (participates in β ladder)trans-92.5130.5177.3-56.6-69.3000111.7R13 V67 Q82 P89 F125 W126 W131R13-Y91 HydrophobicContact CB-CD2 4.37Å; R13-Y91 PolarHBondContact N-O 3.09Å; V67-Y91 HydrophobicContact CG1-CE1 4.46Å; V67-Y91 HydrophobicContact CG2-CD1 3.98Å; V67-Y91 HydrophobicContact CG2-CE1 4.08Å; Q82-Y91 HydrophobicContact CB-CD1 3.89Å; Q82-Y91 HydrophobicContact CB-CE1 4.04Å; P89-Y91 HydrophobicContact CB-CE1 4.01Å; P89-Y91 HydrophobicContact CB-CE2 4.01Å; P89-Y91 HydrophobicContact CG-CE2 3.89Å; P89-Y91 WeakPolarHBondContact CG-OH 3.18Å; Y91-F125 AromaticContact CD1-CD1 3.67Å; Y91-F125 HydrophobicContact CD1-CD1 3.67Å; Y91-F125 AromaticContact CD1-CE1 3.72Å; Y91-F125 HydrophobicContact CD1-CE1 3.72Å; Y91-F125 HydrophobicContact CD2-CD1 4.09Å; Y91-F125 AromaticContact CE1-CD1 3.72Å; Y91-F125 HydrophobicContact CE1-CD1 3.72Å; Y91-F125 HydrophobicContact CE1-CE1 4.2Å; Y91-F125 HydrophobicContact CE2-CD1 4.12Å; Y91-F125 AromaticContact CG-CD1 3.85Å; Y91-F125 HydrophobicContact CG-CD1 3.85Å; Y91-F125 AromaticContact CG-CE1 3.9Å; Y91-F125 HydrophobicContact CG-CE1 3.9Å; Y91-F125 AromaticContact CZ-CD1 3.94Å; Y91-W126 PolarHBondContact OH-N 2.68Å; Y91-W131 WeakPolarHBondContact OH-CZ3 3.45Å
92I95.6Very high92.3Very high0 Ų038.5 Ų38.50%021%0.207CC..EExtended strand (participates in β ladder)trans-131.4137.6-175.6-53.2176.4000108.4F10 I11 F30 A80 F81 I83 L90F10-I92 HydrophobicContact CB-CG2 3.37Å; F10-I92 HydrophobicContact CD1-CG2 4.14Å; F10-I92 HydrophobicContact CD2-CG2 3.67Å; F10-I92 HydrophobicContact CE2-CG2 4.46Å; F10-I92 HydrophobicContact CG-CG2 3.47Å; F10-I92 VanDerWaalsContact CG-CG2 3.47Å; I11-I92 CarbonylContact O-C 3.56Å; I11-I92 WeakPolarHBondContact O-CA 3.15Å; F30-I92 HydrophobicContact CD1-CD1 4.29Å; F30-I92 HydrophobicContact CE1-CD1 3.62Å; F30-I92 HydrophobicContact CE1-CG1 4.26Å; F30-I92 HydrophobicContact CE2-CG2 4.37Å; F30-I92 HydrophobicContact CZ-CD1 3.93Å; F30-I92 HydrophobicContact CZ-CG1 4.06Å; F30-I92 HydrophobicContact CZ-CG2 4.34Å; A80-I92 CarbonylContact C-O 3.53Å; A80-I92 WeakPolarHBondContact CA-O 3.27Å; F81-I92 HydrophobicContact CD1-CB 4.07Å; F81-I92 HydrophobicContact CD1-CG2 4.34Å; F81-I92 WeakPolarHBondContact CD1-O 3.42Å; F81-I92 HydrophobicContact CE1-CB 3.6Å; F81-I92 HydrophobicContact CE1-CG2 3.47Å; F81-I92 VanDerWaalsContact CE1-CG2 3.47Å; F81-I92 HydrophobicContact CE2-CB 4.13Å; F81-I92 HydrophobicContact CE2-CD1 3.86Å; F81-I92 HydrophobicContact CE2-CG1 4.46Å; F81-I92 HydrophobicContact CZ-CB 3.64Å; F81-I92 HydrophobicContact CZ-CD1 3.8Å; F81-I92 HydrophobicContact CZ-CG1 4.28Å; F81-I92 HydrophobicContact CZ-CG2 3.57Å; F81-I92 PolarHBondContact N-O 2.9Å; F81-I92 PolarHBondContact O-N 3.38Å; I83-I92 HydrophobicContact CD1-CD1 3.75Å; I83-I92 HydrophobicContact CG1-CD1 4.28Å; L90-I92 HydrophobicContact CD1-CG1 4.47Å; L90-I92 HydrophobicContact CD2-CD1 4.07Å; L90-I92 HydrophobicContact CD2-CG1 4.46Å; L90-I92 HydrophobicContact CG-CD1 4.1Å; L90-I92 HydrophobicContact CG-CG1 3.99Å
93F95.4Very high92.4Very high3 Ų338.8 Ų38.81%0.01321%0.208CC..EExtended strand (participates in β ladder)trans-117.1124.9178.3-51.3-99.6000110.5F10 I11 R13 Y25 R77 Y79 A80 F125F10-F93 WeakPolarHBondContact CD1-O 3.41Å; I11-F93 HydrophobicContact CB-CB 4.16Å; I11-F93 HydrophobicContact CB-CD2 4.24Å; I11-F93 HydrophobicContact CG2-CD2 4.14Å; I11-F93 PolarHBondContact N-O 2.86Å; I11-F93 WeakPolarHBondContact O-CD2 3.39Å; I11-F93 PolarHBondContact O-N 2.85Å; R13-F93 HydrophobicContact CB-CE2 4.02Å; Y25-F93 HydrophobicContact CD1-CD2 4.31Å; Y25-F93 AromaticContact CD1-CE2 3.7Å; Y25-F93 HydrophobicContact CD1-CE2 3.7Å; Y25-F93 HydrophobicContact CD1-CZ 4.21Å; Y25-F93 HydrophobicContact CE1-CD2 4.5Å; Y25-F93 AromaticContact CE1-CE2 3.53Å; Y25-F93 HydrophobicContact CE1-CE2 3.53Å; Y25-F93 AromaticContact CE1-CZ 3.59Å; Y25-F93 HydrophobicContact CE1-CZ 3.59Å; R77-F93 HydrophobicContact CB-CD1 3.85Å; R77-F93 HydrophobicContact CB-CE1 3.98Å; R77-F93 HydrophobicContact CG-CD1 4.05Å; R77-F93 HydrophobicContact CG-CE1 4.19Å; R77-F93 HydrophobicContact CG-CG 4.36Å; R77-F93 WeakPolarHBondContact O-CD1 3.3Å; Y79-F93 WeakPolarHBondContact O-CA 3.33Å; A80-F93 HydrophobicContact CB-CD1 3.57Å; A80-F93 HydrophobicContact CB-CE1 3.54Å; A80-F93 HydrophobicContact CB-CG 4.49Å; A80-F93 HydrophobicContact CB-CZ 4.43Å; F93-F125 HydrophobicContact CE1-CE1 4.25Å; F93-F125 AromaticContact CE1-CZ 3.81Å; F93-F125 HydrophobicContact CE1-CZ 3.81Å; F93-F125 AromaticContact CZ-CE1 3.89Å; F93-F125 HydrophobicContact CZ-CE1 3.89Å; F93-F125 AromaticContact CZ-CZ 3.9Å; F93-F125 HydrophobicContact CZ-CZ 3.9Å
94A94.6Very high92.4Very high1 Ų139.3 Ų39.31%0.00821%0.211CC..EExtended strand (participates in β ladder)trans-88.3154.1175.400000111.8F10 Y79 T96 I99 R100F10-A94 HydrophobicContact CD1-CB 4.1Å; F10-A94 HydrophobicContact CE1-CB 3.67Å; Y79-A94 PolarHBondContact O-N 2.75Å; A94-T96 VanDerWaalsContact C-N 3.33Å; A94-T96 WeakPolarHBondContact CB-O 3.42Å; A94-I99 HydrophobicContact CB-CB 4.34Å; A94-I99 HydrophobicContact CB-CG2 4.21Å; A94-R100 HydrophobicContact CB-CB 3.76Å
95K91Very high92.5Very high120 Ų12044.9 Ų44.952%0.52224%0.235SC..SBendtrans-68.8-33.3175-66.8-179.6179.5176.40112.4Y79 I99Y79-K95 WeakPolarHBondContact CD2-O 3.44Å; K95-I99 HydrophobicContact CB-CD1 4.41Å
96T92.1Very high92.6Very high56 Ų5647.1 Ų47.134%0.34425%0.245SC..SBendtrans-137.7160.4179.768.50000111.1A94 D98 I99 R100A94-T96 VanDerWaalsContact C-N 3.33Å; A94-T96 WeakPolarHBondContact CB-O 3.42Å; T96-D98 VanDerWaalsContact C-N 3.3Å; T96-D98 PolarHBondContact O-N 3.3Å; T96-I99 PolarHBondContact O-N 3.39Å; T96-I99 WeakPolarHBondContact OG1-CD1 3.4Å; T96-I99 WeakPolarHBondContact OG1-CG1 3.49Å; T96-I99 PolarHBondContact OG1-N 2.98Å; T96-R100 PolarHBondContact O-N 2.94Å
97D92.8Very high93.2Very high70 Ų7043.7 Ų43.737%0.37423%0.226SC..Hα-helixtrans-65.3-34.1175.9-164.333.7000112.5Y79 I99 R100 A101Y79-D97 HydrophobicContact CD1-CB 3.69Å; Y79-D97 HydrophobicContact CE1-CB 3.66Å; D97-I99 PolarHBondContact O-N 3.03Å; D97-R100 WeakPolarHBondContact O-CB 3.35Å; D97-R100 PolarHBondContact O-N 3.03Å; D97-R100 IonicContact OD1-CZ 2.9Å; D97-R100 IonicContact OD1-NE 2.69Å; D97-R100 PolarHBondContact OD1-NE 2.96Å; D97-R100 IonicContact OD1-NH2 3.59Å; D97-R100 PolarHBondContact OD1-NH2 2.93Å; D97-A101 WeakPolarHBondContact O-CB 3.31Å; D97-A101 PolarHBondContact O-N 3.1Å
98D93.4Very high93.8Very high130 Ų13041.7 Ų41.770%0.69522%0.216SC*.Hα-helixtrans-63.1-43.6179.4-62.4-40000111.7T96 A101 S102T96-D98 VanDerWaalsContact C-N 3.3Å; T96-D98 PolarHBondContact O-N 3.3Å; D98-A101 PolarHBondContact O-N 2.93Å; D98-S102 VanDerWaalsContact O-CB 3.28Å; D98-S102 WeakPolarHBondContact O-CB 3.44Å; D98-S102 PolarHBondContact O-N 3.27Å
99I94.5Very high94Very high41 Ų4145.4 Ų45.421%0.2123%0.232CC..Hα-helixtrans-63.3-46.8175.7-65.8168.4000109.5E8 F10 A94 K95 T96 D97 A101 S102 W103E8-I99 HydrophobicContact CG-CG2 3.81Å; F10-I99 HydrophobicContact CE1-CG2 3.56Å; F10-I99 HydrophobicContact CZ-CG2 3.78Å; A94-I99 HydrophobicContact CB-CB 4.34Å; A94-I99 HydrophobicContact CB-CG2 4.21Å; K95-I99 HydrophobicContact CB-CD1 4.41Å; T96-I99 PolarHBondContact O-N 3.39Å; T96-I99 WeakPolarHBondContact OG1-CD1 3.4Å; T96-I99 WeakPolarHBondContact OG1-CG1 3.49Å; T96-I99 PolarHBondContact OG1-N 2.98Å; D97-I99 PolarHBondContact O-N 3.03Å; I99-A101 PolarHBondContact O-N 2.84Å; I99-S102 PolarHBondContact O-N 2.76Å; I99-W103 VanDerWaalsContact O-CD1 3.29Å; I99-W103 PolarHBondContact O-N 2.84Å
100R96.1Very high94.1Very high35 Ų3547.8 Ų47.813%0.13224%0.244CC..Hα-helixtrans-55.9-51.5176.5-179.4175.367.1168.7-0.2111.5A80 F81 A94 T96 D97 S102 W103 I104A80-R100 WeakPolarHBondContact O-CD 3.42Å; A80-R100 PolarHBondContact O-NH1 2.57Å; A80-R100 VanDerWaalsContact O-NH1 3.16Å; F81-R100 HydrophobicContact CB-CG 4.19Å; F81-R100 HydrophobicContact CD1-CG 3.99Å; F81-R100 HydrophobicContact CG-CG 4.4Å; A94-R100 HydrophobicContact CB-CB 3.76Å; T96-R100 PolarHBondContact O-N 2.94Å; D97-R100 WeakPolarHBondContact O-CB 3.35Å; D97-R100 PolarHBondContact O-N 3.03Å; D97-R100 IonicContact OD1-CZ 2.9Å; D97-R100 IonicContact OD1-NE 2.69Å; D97-R100 PolarHBondContact OD1-NE 2.96Å; D97-R100 IonicContact OD1-NH2 3.59Å; D97-R100 PolarHBondContact OD1-NH2 2.93Å; R100-S102 PolarHBondContact O-N 2.91Å; R100-W103 PolarHBondContact O-N 3.45Å; R100-I104 HydrophobicContact CG-CD1 3.71Å; R100-I104 HydrophobicContact CG-CG1 4.39Å; R100-I104 WeakPolarHBondContact O-CB 3.24Å; R100-I104 VanDerWaalsContact O-CG1 3.28Å; R100-I104 WeakPolarHBondContact O-CG1 3.44Å; R100-I104 PolarHBondContact O-N 2.91Å
101A94.1Very high94.1Very high52 Ų5248 Ų4843%0.4325%0.245SC..Hα-helixtrans-62.9-42.3-177.500000111.7D97 D98 I99 K105D97-A101 WeakPolarHBondContact O-CB 3.31Å; D97-A101 PolarHBondContact O-N 3.1Å; D98-A101 PolarHBondContact O-N 2.93Å; I99-A101 PolarHBondContact O-N 2.84Å; A101-K105 VanDerWaalsContact O-CB 3.26Å; A101-K105 WeakPolarHBondContact O-CB 3.27Å; A101-K105 PolarHBondContact O-N 3.33Å
102S95.6Very high93.7Very high61 Ų6155.3 Ų55.343%0.42727%0.273SS..Hα-helixtrans-60.6-48.2176.4-174.70000112D98 I99 R100 K105 K106D98-S102 VanDerWaalsContact O-CB 3.28Å; D98-S102 WeakPolarHBondContact O-CB 3.44Å; D98-S102 PolarHBondContact O-N 3.27Å; I99-S102 PolarHBondContact O-N 2.76Å; R100-S102 PolarHBondContact O-N 2.91Å; S102-K105 PolarHBondContact O-N 3.33Å; S102-K106 PolarHBondContact O-N 2.82Å
103W96.6Very high93.3Very high5 Ų563 Ų632%0.01931%0.306CS..Hα-helixtrans-66.8-43.5179.2-87.277.1000113.1M6 E8 F10 F30 L32 I37 F81 I99 R100 K105 K106 L107M6-W103 HydrophobicContact CB-CH2 4.05Å; M6-W103 HydrophobicContact CB-CZ2 3.68Å; M6-W103 VanDerWaalsContact CE-CD1 3.43Å; M6-W103 HydrophobicContact CE-CD2 4.22Å; M6-W103 HydrophobicContact CE-CG 3.94Å; M6-W103 HydrophobicContact SD-CD2 4.4Å; M6-W103 HydrophobicContact SD-CG 4.45Å; E8-W103 HydrophobicContact CB-CZ2 3.5Å; F10-W103 AromaticContact CE2-CD2 3.56Å; F10-W103 HydrophobicContact CE2-CD2 3.56Å; F10-W103 AromaticContact CE2-CE2 3.53Å; F10-W103 AromaticContact CE2-CE3 3.84Å; F10-W103 HydrophobicContact CE2-CE3 3.84Å; F10-W103 HydrophobicContact CE2-CG 4.05Å; F10-W103 HydrophobicContact CE2-CH2 4.09Å; F10-W103 AromaticContact CE2-CZ2 3.82Å; F10-W103 HydrophobicContact CE2-CZ2 3.82Å; F10-W103 HydrophobicContact CE2-CZ3 4.1Å; F10-W103 AromaticContact CE2-NE1 3.95Å; F10-W103 HydrophobicContact CZ-CB 4.44Å; F10-W103 AromaticContact CZ-CD1 3.61Å; F10-W103 AromaticContact CZ-CD2 3.69Å; F10-W103 HydrophobicContact CZ-CD2 3.69Å; F10-W103 AromaticContact CZ-CE2 3.64Å; F10-W103 HydrophobicContact CZ-CE3 4.4Å; F10-W103 AromaticContact CZ-CG 3.68Å; F10-W103 HydrophobicContact CZ-CG 3.68Å; F10-W103 HydrophobicContact CZ-CZ2 4.32Å; F10-W103 AromaticContact CZ-NE1 3.56Å; F30-W103 HydrophobicContact CB-CH2 3.96Å; F30-W103 HydrophobicContact CB-CZ3 4.33Å; L32-W103 HydrophobicContact CB-CH2 4.04Å; L32-W103 HydrophobicContact CB-CZ3 3.86Å; I37-W103 HydrophobicContact CD1-CE3 4.3Å; I37-W103 HydrophobicContact CD1-CZ3 3.74Å; I37-W103 HydrophobicContact CG1-CZ3 4.37Å; F81-W103 HydrophobicContact CZ-CB 4.48Å; I99-W103 VanDerWaalsContact O-CD1 3.29Å; I99-W103 PolarHBondContact O-N 2.84Å; R100-W103 PolarHBondContact O-N 3.45Å; W103-K105 VanDerWaalsContact C-N 3.32Å; W103-K105 PolarHBondContact O-N 2.94Å; W103-K106 PolarHBondContact O-N 3.33Å; W103-L107 HydrophobicContact CE3-CD1 4.43Å; W103-L107 WeakPolarHBondContact O-CB 3.26Å; W103-L107 WeakPolarHBondContact O-CG 3.38Å; W103-L107 PolarHBondContact O-N 2.8Å
104I95.3Very high93.1Very high12 Ų1264.4 Ų64.46%0.06231%0.314CS..Hα-helixtrans-60.1-46175.2-69.4172000110.1V64 T66 F81 R100 K106 L107 K108V64-I104 HydrophobicContact CG1-CG1 4.37Å; V64-I104 HydrophobicContact CG1-CG2 4.37Å; T66-I104 HydrophobicContact CG2-CD1 3.54Å; F81-I104 HydrophobicContact CB-CD1 3.64Å; F81-I104 HydrophobicContact CB-CG1 3.93Å; F81-I104 HydrophobicContact CD2-CG1 4Å; F81-I104 HydrophobicContact CG-CD1 4.23Å; F81-I104 HydrophobicContact CG-CG1 4.02Å; R100-I104 HydrophobicContact CG-CD1 3.71Å; R100-I104 HydrophobicContact CG-CG1 4.39Å; R100-I104 WeakPolarHBondContact O-CB 3.24Å; R100-I104 VanDerWaalsContact O-CG1 3.28Å; R100-I104 WeakPolarHBondContact O-CG1 3.44Å; R100-I104 PolarHBondContact O-N 2.91Å; I104-K106 PolarHBondContact O-N 3.47Å; I104-L107 PolarHBondContact O-N 3.1Å; I104-K108 HydrophobicContact CG2-CD 3.87Å; I104-K108 HydrophobicContact CG2-CG 4.25Å; I104-K108 VanDerWaalsContact O-CB 3.3Å; I104-K108 WeakPolarHBondContact O-CB 3.43Å; I104-K108 VanDerWaalsContact O-CG 3.29Å; I104-K108 WeakPolarHBondContact O-CG 3.32Å; I104-K108 PolarHBondContact O-N 2.92Å
105K94.1Very high92.5Very high134 Ų13474.3 Ų74.358%0.58336%0.357SS*.Hα-helixtrans-58.5-49.9178.6-178.2-176.8175.7-173.60110.8A101 S102 W103 K108 E109A101-K105 VanDerWaalsContact O-CB 3.26Å; A101-K105 WeakPolarHBondContact O-CB 3.27Å; A101-K105 PolarHBondContact O-N 3.33Å; S102-K105 PolarHBondContact O-N 3.33Å; W103-K105 VanDerWaalsContact C-N 3.32Å; W103-K105 PolarHBondContact O-N 2.94Å; K105-K108 PolarHBondContact O-N 2.8Å; K105-E109 WeakPolarHBondContact CE-OE1 3.39Å; K105-E109 WeakPolarHBondContact O-CG 3.47Å; K105-E109 PolarHBondContact O-N 3.07Å
106K94.6Very high92.2Very high66 Ų6673.9 Ų73.929%0.28736%0.361SS..Hα-helixtrans-64.3-44.8-178.6-170.565.6176.5177.70112.5M6 L32 S102 W103 I104 E109 L110M6-K106 HydrophobicContact CG-CG 4.37Å; M6-K106 HydrophobicContact SD-CB 3.51Å; M6-K106 VanDerWaalsContact SD-CB 3.51Å; M6-K106 HydrophobicContact SD-CG 3.59Å; M6-K106 VanDerWaalsContact SD-CG 3.59Å; L32-K106 HydrophobicContact CD2-CB 4.43Å; L32-K106 HydrophobicContact CD2-CG 3.83Å; S102-K106 PolarHBondContact O-N 2.82Å; W103-K106 PolarHBondContact O-N 3.33Å; I104-K106 PolarHBondContact O-N 3.47Å; K106-E109 WeakPolarHBondContact O-CB 3.45Å; K106-E109 PolarHBondContact O-N 2.93Å; K106-L110 HydrophobicContact CG-CD1 4.39Å; K106-L110 WeakPolarHBondContact O-CG 3.34Å; K106-L110 PolarHBondContact O-N 2.8Å; K106-L110 VanDerWaalsContact O-N 3.12Å
107L94.6Very high92Very high0 Ų074.2 Ų74.20%036%0.36CS..Hα-helixtrans-61.2-46.5176.5-78166.7000111.1L32 I37 L58 V64 F81 I83 W103 I104 E109 L110 V111L32-L107 HydrophobicContact CD1-CD2 3.67Å; L32-L107 HydrophobicContact CD2-CD2 4.15Å; L32-L107 HydrophobicContact CD2-CG 4.33Å; I37-L107 HydrophobicContact CD1-CD1 4.4Å; I37-L107 HydrophobicContact CD1-CD2 4.37Å; L58-L107 HydrophobicContact CD2-CD2 4.06Å; V64-L107 HydrophobicContact CB-CB 4.48Å; V64-L107 HydrophobicContact CG1-CB 4.04Å; V64-L107 HydrophobicContact CG1-CD1 4.08Å; V64-L107 HydrophobicContact CG2-CB 4.14Å; F81-L107 HydrophobicContact CE2-CD1 4.12Å; I83-L107 HydrophobicContact CD1-CD1 3.75Å; I83-L107 HydrophobicContact CG1-CD1 4.27Å; W103-L107 HydrophobicContact CE3-CD1 4.43Å; W103-L107 WeakPolarHBondContact O-CB 3.26Å; W103-L107 WeakPolarHBondContact O-CG 3.38Å; W103-L107 PolarHBondContact O-N 2.8Å; I104-L107 PolarHBondContact O-N 3.1Å; L107-E109 VanDerWaalsContact C-N 3.3Å; L107-E109 PolarHBondContact O-N 3.01Å; L107-L110 PolarHBondContact O-N 3.11Å; L107-L110 VanDerWaalsContact O-N 3.14Å; L107-V111 WeakPolarHBondContact O-CG2 3.37Å; L107-V111 PolarHBondContact O-N 2.77Å
108K93.1Very high91.7Very high75 Ų7573.4 Ų73.433%0.32635%0.354SS..Hα-helixtrans-58.5-40175.4-77.6-177.7175.4-177.40112.3V64 E65 I104 K105 L110 R112V64-K108 HydrophobicContact CB-CG 4.32Å; V64-K108 WeakPolarHBondContact O-CE 3.49Å; E65-K108 VanDerWaalsContact CD-NZ 3.27Å; E65-K108 IonicContact OE1-NZ 3.7Å; E65-K108 PolarHBondContact OE1-NZ 3.49Å; E65-K108 IonicContact OE2-NZ 2.95Å; I104-K108 HydrophobicContact CG2-CD 3.87Å; I104-K108 HydrophobicContact CG2-CG 4.25Å; I104-K108 VanDerWaalsContact O-CB 3.3Å; I104-K108 WeakPolarHBondContact O-CB 3.43Å; I104-K108 VanDerWaalsContact O-CG 3.29Å; I104-K108 WeakPolarHBondContact O-CG 3.32Å; I104-K108 PolarHBondContact O-N 2.92Å; K105-K108 PolarHBondContact O-N 2.8Å; K108-L110 VanDerWaalsContact C-N 3.33Å; K108-L110 PolarHBondContact O-N 3.38Å; K108-R112 WeakPolarHBondContact O-CB 3.26Å; K108-R112 PolarHBondContact O-N 2.93Å; K108-R112 VanDerWaalsContact O-N 3.12Å
109E92.1Very high91.4Very high83 Ų8374 Ų7439%0.38835%0.353SS..Hα-helixtrans-62-39.4175.9-77.1171.8-17300112.5K105 K106 L107 R112K105-E109 WeakPolarHBondContact CE-OE1 3.39Å; K105-E109 WeakPolarHBondContact O-CG 3.47Å; K105-E109 PolarHBondContact O-N 3.07Å; K106-E109 WeakPolarHBondContact O-CB 3.45Å; K106-E109 PolarHBondContact O-N 2.93Å; L107-E109 VanDerWaalsContact C-N 3.3Å; L107-E109 PolarHBondContact O-N 3.01Å; E109-R112 WeakPolarHBondContact O-CD 3.38Å; E109-R112 WeakPolarHBondContact O-CG 3.31Å; E109-R112 PolarHBondContact O-NE 3.23Å
110L92.1Very high91.2Very high54 Ų5476.2 Ų76.228%0.28336%0.361SS..Hα-helixtrans-74.9-37.1-179.6-65.9169.1000112.5L5 L32 L58 K106 L107 K108L5-L110 HydrophobicContact CD1-CD1 3.75Å; L5-L110 HydrophobicContact CD1-CD2 4.05Å; L32-L110 HydrophobicContact CD1-CD1 3.97Å; L32-L110 HydrophobicContact CD2-CD1 3.87Å; L32-L110 HydrophobicContact CG-CD1 4.06Å; L58-L110 HydrophobicContact CD1-CB 3.9Å; L58-L110 HydrophobicContact CD1-CD1 3.75Å; L58-L110 HydrophobicContact CD1-CG 4.33Å; K106-L110 HydrophobicContact CG-CD1 4.39Å; K106-L110 WeakPolarHBondContact O-CG 3.34Å; K106-L110 PolarHBondContact O-N 2.8Å; K106-L110 VanDerWaalsContact O-N 3.12Å; L107-L110 PolarHBondContact O-N 3.11Å; L107-L110 VanDerWaalsContact O-N 3.14Å; K108-L110 VanDerWaalsContact C-N 3.33Å; K108-L110 PolarHBondContact O-N 3.38Å
111V92.8Very high91Very high4 Ų474.9 Ų74.92%0.02436%0.356CS..Hα-helixtrans-92.6-2.1-175.1-54.70000114.2L58 I61 V64 L107 F113 N114 L117L58-V111 HydrophobicContact CB-CG1 4.38Å; L58-V111 HydrophobicContact CD2-CG1 4.42Å; I61-V111 HydrophobicContact CB-CG1 3.83Å; I61-V111 HydrophobicContact CD1-CG1 4.01Å; I61-V111 HydrophobicContact CG1-CG1 4.44Å; I61-V111 HydrophobicContact CG2-CB 4.45Å; I61-V111 HydrophobicContact CG2-CG1 3.99Å; I61-V111 HydrophobicContact CG2-CG2 4.34Å; V64-V111 HydrophobicContact CG2-CG2 4.48Å; L107-V111 WeakPolarHBondContact O-CG2 3.37Å; L107-V111 PolarHBondContact O-N 2.77Å; V111-F113 PolarHBondContact O-N 2.84Å; V111-N114 WeakPolarHBondContact O-CB 3.47Å; V111-N114 PolarHBondContact O-N 2.72Å; V111-L117 HydrophobicContact CG2-CD2 4.36Å
112R88.6Confident91Very high160 Ų16072.6 Ų72.660%0.60434%0.337SS*.THydrogen-bonded Turntrans-57.8-18.9-172.469-172.8176.2166.41.5115.6K108 E109K108-R112 WeakPolarHBondContact O-CB 3.26Å; K108-R112 PolarHBondContact O-N 2.93Å; K108-R112 VanDerWaalsContact O-N 3.12Å; E109-R112 WeakPolarHBondContact O-CD 3.38Å; E109-R112 WeakPolarHBondContact O-CG 3.31Å; E109-R112 PolarHBondContact O-NE 3.23Å
113F87.2Confident90.9Very high161 Ų16170.2 Ų70.271%0.70632%0.319SS*.THydrogen-bonded Turntrans-107.77.9-179.2-59.8-60000113.4V111V111-F113 PolarHBondContact O-N 2.84Å
114N89.9Confident90.7Very high32 Ų3270.7 Ų70.717%0.17132%0.323CS..  trans-64139.5175.1-70.73.6000110.4L58 E59 I61 V111 D116 L117L58-N114 PolarHBondContact O-ND2 2.76Å; E59-N114 PolarHBondContact O-ND2 2.84Å; I61-N114 PolarHBondContact O-ND2 2.94Å; V111-N114 WeakPolarHBondContact O-CB 3.47Å; V111-N114 PolarHBondContact O-N 2.72Å; N114-D116 VanDerWaalsContact C-N 3.31Å; N114-D116 PolarHBondContact O-N 2.94Å; N114-L117 HydrophobicContact CB-CD2 4.12Å; N114-L117 HydrophobicContact CB-CG 4.02Å; N114-L117 WeakPolarHBondContact O-CG 3.35Å
115K83.2Confident90.4Very high209 Ų20970.3 Ų70.391%0.90932%0.321SS*.THydrogen-bonded Turntrans-70.4-28.9-176.9-65.2179.3-178.9175.40112.8
116D84.8Confident90.2Very high112 Ų11265 Ų6560%0.59930%0.298SS*.THydrogen-bonded Turntrans-105.331.4-171.1-58.3-43.4000113.6K62 N114 M118K62-D116 WeakPolarHBondContact CB-O 2.93Å; K62-D116 WeakPolarHBondContact CG-O 3.42Å; N114-D116 VanDerWaalsContact C-N 3.31Å; N114-D116 PolarHBondContact O-N 2.94Å; D116-M118 PolarHBondContact O-N 3.05Å
117L87.9Confident89.7Confident62 Ų6262.8 Ų62.833%0.32529%0.29SS..  trans-66.5130.9176.2-69.7175.8000111.4K62 V111 N114K62-L117 WeakPolarHBondContact O-CA 3.48Å; V111-L117 HydrophobicContact CG2-CD2 4.36Å; N114-L117 HydrophobicContact CB-CD2 4.12Å; N114-L117 HydrophobicContact CB-CG 4.02Å; N114-L117 WeakPolarHBondContact O-CG 3.35Å
118M86.3Confident89.1Confident54 Ų5467.6 Ų67.627%0.26632%0.315SS..  trans-74.7139.9-179-58.6-166.4-62.100112K62 C63 I84 D116 K120K62-M118 HydrophobicContact CB-CG 3.76Å; K62-M118 HydrophobicContact CB-SD 4.39Å; K62-M118 PolarHBondContact O-N 2.83Å; C63-M118 HydrophobicContact CB-CE 3.41Å; C63-M118 VanDerWaalsContact CB-CE 3.41Å; I84-M118 HydrophobicContact CB-CE 3.84Å; I84-M118 HydrophobicContact CD1-CE 3.4Å; I84-M118 VanDerWaalsContact CD1-CE 3.4Å; I84-M118 HydrophobicContact CG1-CE 4.19Å; I84-M118 HydrophobicContact CG2-CE 3.63Å; I84-M118 HydrophobicContact CG2-SD 4.28Å; D116-M118 PolarHBondContact O-N 3.05Å; M118-K120 WeakPolarHBondContact CB-O 3.29Å
119Q86.4Confident88.6Confident142 Ų14264.6 Ų64.666%0.66431%0.306SS*.SBendtrans-79.8-23.7174.1-62.7178.72.900112.9L147Q119-L147 PolarHBondContact O-N 3.41Å
120K90.3Very high88.5Confident88 Ų8862.2 Ų62.238%0.38330%0.297SS..EExtended strand (participates in β ladder)trans-135.3146.7177.9-56.9-176.5-177.2174.40110.7M118 M142 G143 K145 V146M118-K120 WeakPolarHBondContact CB-O 3.29Å; K120-M142 HydrophobicContact CB-CG 4.28Å; K120-M142 HydrophobicContact CD-CG 4.21Å; K120-M142 HydrophobicContact CD-SD 4.11Å; K120-G143 WeakPolarHBondContact CB-O 3.38Å; K120-G143 VanDerWaalsContact CD-O 3.28Å; K120-G143 WeakPolarHBondContact CD-O 3.4Å; K120-K145 CarbonylContact C-O 3.54Å; K120-K145 WeakPolarHBondContact CA-O 3.28Å; K120-K145 WeakPolarHBondContact CB-O 3.43Å; K120-V146 HydrophobicContact CG-CG2 4.34Å
121Y92.7Very high88.4Confident6 Ų659.9 Ų59.92%0.02428%0.284CS..EExtended strand (participates in β ladder)trans-135.5166.9177.173.3-78.3000111.3E65 P123 G143 C144 K145 L147E65-Y121 HydrophobicContact CB-CD2 3.9Å; E65-Y121 HydrophobicContact CB-CE2 3.65Å; E65-Y121 HydrophobicContact CB-CG 4.49Å; E65-Y121 HydrophobicContact CG-CD1 4.27Å; E65-Y121 HydrophobicContact CG-CD2 4.17Å; E65-Y121 HydrophobicContact CG-CE1 3.92Å; E65-Y121 HydrophobicContact CG-CE2 3.81Å; E65-Y121 HydrophobicContact CG-CG 4.38Å; Y121-P123 HydrophobicContact CE2-CB 4.07Å; Y121-G143 CarbonylContact O-C 3.52Å; Y121-G143 WeakPolarHBondContact O-CA 3.39Å; Y121-C144 PolarHBondContact O-N 2.89Å; Y121-K145 HydrophobicContact CD1-CB 4.45Å; Y121-K145 WeakPolarHBondContact CD1-O 3.5Å; Y121-K145 HydrophobicContact CE1-CB 4.17Å; Y121-K145 HydrophobicContact CE1-CD 4.12Å; Y121-K145 HydrophobicContact CE1-CG 4Å; Y121-K145 HydrophobicContact CE2-CD 4.42Å; Y121-K145 PolarHBondContact N-O 2.93Å; Y121-K145 PolarHBondContact O-N 3.45Å; Y121-K145 WeakPolarHBondContact OH-CD 3.43Å; Y121-K145 WeakPolarHBondContact OH-CE 3.46Å; Y121-K145 PolarHBondContact OH-NZ 2.79Å; Y121-K145 VanDerWaalsContact OH-NZ 3.13Å; Y121-L147 HydrophobicContact CD1-CD1 3.68Å; Y121-L147 HydrophobicContact CE1-CD1 3.97Å; Y121-L147 HydrophobicContact CG-CD1 4.46Å
122H93.3Very high88.2Confident5 Ų563.5 Ų63.52%0.02330%0.303CS..  trans-98119.3175.3-73.2-59.8000110Q82 C124 W131 C133 C134 Q136 A141 M142 G143 C144Q82-H122 PolarHBondContact NE2-O 2.82Å; H122-C124 VanDerWaalsContact C-N 3.29Å; H122-C124 PolarHBondContact O-N 3.18Å; H122-W131 HydrophobicContact CB-CD2 3.68Å; H122-W131 HydrophobicContact CB-CE3 3.3Å; H122-W131 HydrophobicContact CB-CG 4.42Å; H122-W131 HydrophobicContact CB-CH2 3.84Å; H122-W131 HydrophobicContact CB-CZ2 4.2Å; H122-W131 HydrophobicContact CB-CZ3 3.37Å; H122-W131 AromaticContact CD2-CD1 3.72Å; H122-W131 AromaticContact CD2-CD2 3.41Å; H122-W131 VanDerWaalsContact CD2-CD2 3.41Å; H122-W131 AromaticContact CD2-CE2 3.14Å; H122-W131 AromaticContact CD2-CE3 3.99Å; H122-W131 AromaticContact CD2-CG 3.79Å; H122-W131 AromaticContact CD2-CZ2 3.5Å; H122-W131 VanDerWaalsContact CD2-CZ2 3.5Å; H122-W131 WeakPolarHBondContact CD2-CZ2 3.39Å; H122-W131 AromaticContact CD2-NE1 3.36Å; H122-W131 PolarHBondContact CD2-NE1 2.96Å; H122-W131 AromaticContact CE1-CD1 3.94Å; H122-W131 AromaticContact CG-CD2 3.45Å; H122-W131 VanDerWaalsContact CG-CD2 3.45Å; H122-W131 AromaticContact CG-CE2 3.71Å; H122-W131 AromaticContact CG-CE3 3.67Å; H122-W131 AromaticContact CG-CG 3.82Å; H122-W131 AromaticContact NE2-CD1 3.53Å; H122-W131 AromaticContact NE2-CE2 3.77Å; H122-W131 AromaticContact NE2-CG 3.88Å; H122-W131 AromaticContact NE2-NE1 3.46Å; H122-W131 PolarHBondContact NE2-NE1 2.92Å; H122-C133 PolarHBondContact ND1-SG 3.43Å; H122-C134 PolarHBondContact CE1-SG 3.38Å; H122-Q136 PolarHBondContact CE1-OE1 3.18Å; H122-Q136 PolarHBondContact NE2-OE1 3.29Å; H122-Q136 VanDerWaalsContact NE2-OE1 3.14Å; H122-A141 PolarHBondContact NE2-O 2.85Å; H122-M142 PolarHBondContact CE1-O 3.18Å; H122-M142 PolarHBondContact NE2-O 2.88Å; H122-G143 VanDerWaalsContact CE1-CA 3.49Å; H122-G143 WeakPolarHBondContact CE1-CA 3.23Å; H122-G143 WeakPolarHBondContact NE2-CA 3.46Å; H122-C144 PolarHBondContact CE1-N 2.86Å; H122-C144 PolarHBondContact ND1-N 2.94Å
123P92.4Very high88.3Confident10 Ų1057.7 Ų57.77%0.06529%0.287CS..SBendtrans-79.3-6.9-17632-36.2000114.1V67 Q68 Y121 C133 C144 K145V67-P123 CarbonylContact C-O 3.58Å; V67-P123 WeakPolarHBondContact CA-O 3.4Å; Q68-P123 HydrophobicContact CG-CB 4.37Å; Q68-P123 PolarHBondContact N-O 3.41Å; Y121-P123 HydrophobicContact CE2-CB 4.07Å; P123-C133 HydrophobicContact CG-CB 3.97Å; P123-C144 VanDerWaalsContact CD-SG 3.54Å; P123-K145 HydrophobicContact CB-CD 4.16Å; P123-K145 HydrophobicContact CG-CB 4.31Å; P123-K145 HydrophobicContact CG-CD 4.26Å
124C92.4Very high88.3Confident15 Ų1552.1 Ų52.110%0.10127%0.267CS..SBendtrans-116.7173-179.2-60.10000111.8Q68 H122 W131 L132 C133Q68-C124 PolarHBondContact OE1-SG 2.88Å; H122-C124 VanDerWaalsContact C-N 3.29Å; H122-C124 PolarHBondContact O-N 3.18Å; C124-W131 VanDerWaalsContact O-CZ3 3.24Å; C124-W131 WeakPolarHBondContact O-CZ3 3.23Å; C124-L132 HydrophobicContact CB-CB 3.88Å; C124-C133 HydrophobicContact CB-CB 3.74Å
125F90.9Very high88.3Confident4 Ų456.4 Ų56.42%0.01829%0.286CS..  trans-69.2146.5177.6-63.7-73.6000112.9V67 Q68 E70 A80 Y91 F93 V127 L132V67-F125 HydrophobicContact CB-CE1 4.45Å; V67-F125 HydrophobicContact CB-CZ 4.33Å; V67-F125 HydrophobicContact CG1-CD1 3.93Å; V67-F125 HydrophobicContact CG1-CD2 4.03Å; V67-F125 HydrophobicContact CG1-CE1 3.7Å; V67-F125 HydrophobicContact CG1-CE2 3.77Å; V67-F125 HydrophobicContact CG1-CG 4.1Å; V67-F125 HydrophobicContact CG1-CZ 3.61Å; Q68-F125 WeakPolarHBondContact O-CE2 3.32Å; E70-F125 HydrophobicContact CG-CD2 3.79Å; E70-F125 HydrophobicContact CG-CE2 3.75Å; A80-F125 HydrophobicContact CB-CE1 4.47Å; A80-F125 HydrophobicContact CB-CZ 3.85Å; Y91-F125 AromaticContact CD1-CD1 3.67Å; Y91-F125 HydrophobicContact CD1-CD1 3.67Å; Y91-F125 AromaticContact CD1-CE1 3.72Å; Y91-F125 HydrophobicContact CD1-CE1 3.72Å; Y91-F125 HydrophobicContact CD2-CD1 4.09Å; Y91-F125 AromaticContact CE1-CD1 3.72Å; Y91-F125 HydrophobicContact CE1-CD1 3.72Å; Y91-F125 HydrophobicContact CE1-CE1 4.2Å; Y91-F125 HydrophobicContact CE2-CD1 4.12Å; Y91-F125 AromaticContact CG-CD1 3.85Å; Y91-F125 HydrophobicContact CG-CD1 3.85Å; Y91-F125 AromaticContact CG-CE1 3.9Å; Y91-F125 HydrophobicContact CG-CE1 3.9Å; Y91-F125 AromaticContact CZ-CD1 3.94Å; F93-F125 HydrophobicContact CE1-CE1 4.25Å; F93-F125 AromaticContact CE1-CZ 3.81Å; F93-F125 HydrophobicContact CE1-CZ 3.81Å; F93-F125 AromaticContact CZ-CE1 3.89Å; F93-F125 HydrophobicContact CZ-CE1 3.89Å; F93-F125 AromaticContact CZ-CZ 3.9Å; F93-F125 HydrophobicContact CZ-CZ 3.9Å; F125-V127 HydrophobicContact CB-CG2 3.75Å; F125-L132 HydrophobicContact CB-CD1 4.28Å; F125-L132 WeakPolarHBondContact O-CG 3.48Å; F125-L132 PolarHBondContact O-N 3.44Å; F125-L132 VanDerWaalsContact O-N 3.08Å
126W88.3Confident88.5Confident24 Ų2449.7 Ų49.79%0.09126%0.258CS..EExtended strand (participates in β ladder)trans-80.4123.2157.8178.3-91.9000108.7R13 Y91 G129 V130 W131 Q136 E137 V138 K139R13-W126 PolarHBondContact NH1-O 2.84Å; Y91-W126 PolarHBondContact OH-N 2.68Å; W126-G129 WeakPolarHBondContact CH2-O 3.32Å; W126-G129 VanDerWaalsContact CZ2-CA 3.43Å; W126-G129 WeakPolarHBondContact CZ2-O 3.33Å; W126-V130 WeakPolarHBondContact CA-O 3.39Å; W126-V130 VanDerWaalsContact CE3-C 3.42Å; W126-W131 HydrophobicContact CB-CD2 4.31Å; W126-W131 HydrophobicContact CB-CE3 4.04Å; W126-W131 HydrophobicContact CB-CH2 4.23Å; W126-W131 HydrophobicContact CB-CZ2 4.42Å; W126-W131 HydrophobicContact CB-CZ3 4.02Å; W126-W131 HydrophobicContact CE3-CB 4.31Å; W126-W131 AromaticContact CE3-CD1 3.34Å; W126-W131 AromaticContact CE3-CD2 3.62Å; W126-W131 HydrophobicContact CE3-CD2 3.62Å; W126-W131 AromaticContact CE3-CE2 3.52Å; W126-W131 HydrophobicContact CE3-CE3 4.45Å; W126-W131 AromaticContact CE3-CG 3.52Å; W126-W131 HydrophobicContact CE3-CG 3.52Å; W126-W131 HydrophobicContact CE3-CZ2 4.31Å; W126-W131 AromaticContact CE3-NE1 3.31Å; W126-W131 VanDerWaalsContact CE3-NE1 3.31Å; W126-W131 AromaticContact CZ3-CD1 3.3Å; W126-W131 HydrophobicContact CZ3-CD2 4.37Å; W126-W131 AromaticContact CZ3-CG 3.88Å; W126-W131 HydrophobicContact CZ3-CG 3.88Å; W126-W131 AromaticContact CZ3-NE1 3.46Å; W126-Q136 VanDerWaalsContact CZ3-O 3.29Å; W126-Q136 WeakPolarHBondContact CZ3-O 3.49Å; W126-E137 VanDerWaalsContact CH2-C 3.44Å; W126-E137 WeakPolarHBondContact CH2-O 3.47Å; W126-V138 VanDerWaalsContact CZ3-C 3.48Å; W126-K139 HydrophobicContact CD2-CB 4.04Å; W126-K139 HydrophobicContact CD2-CG 3.82Å; W126-K139 HydrophobicContact CE3-CB 4.3Å; W126-K139 HydrophobicContact CE3-CG 4.36Å; W126-K139 HydrophobicContact CG-CD 4.46Å; W126-K139 HydrophobicContact CG-CG 4.04Å; W126-K139 VanDerWaalsContact CH2-CA 3.46Å; W126-K139 HydrophobicContact CH2-CB 3.88Å; W126-K139 HydrophobicContact CZ2-CB 3.59Å; W126-K139 HydrophobicContact CZ2-CG 4.19Å; W126-K139 VanDerWaalsContact CZ3-CA 3.48Å; W126-K139 HydrophobicContact CZ3-CB 4.23Å
127V84.8Confident88.6Confident19 Ų1951.9 Ų51.912%0.11527%0.265CS..EExtended strand (participates in β ladder)trans-145.2136.9-176.7-1670000108.5L23 F125 G129 V130 L132L23-V127 HydrophobicContact CD1-CG1 4.27Å; F125-V127 HydrophobicContact CB-CG2 3.75Å; V127-G129 PolarHBondContact O-N 3.28Å; V127-V130 PolarHBondContact N-O 3.23Å; V127-V130 VanDerWaalsContact O-CG2 3.27Å; V127-V130 WeakPolarHBondContact O-CG2 3.36Å; V127-V130 PolarHBondContact O-N 3.28Å; V127-L132 HydrophobicContact CB-CD2 4.41Å; V127-L132 HydrophobicContact CB-CG 4.41Å; V127-L132 HydrophobicContact CG2-CD1 3.71Å; V127-L132 HydrophobicContact CG2-CD2 4.43Å; V127-L132 HydrophobicContact CG2-CG 3.96Å
128D81.9Confident88.5Confident100 Ų10053.4 Ų53.454%0.53528%0.277SS..THydrogen-bonded Turntrans4937.7173.1-55.9-25.5000114.9K19K19-D128 WeakPolarHBondContact CE-O 3.34Å
129G83.6Confident88.3Confident13 Ų1353.2 Ų53.213%0.13427%0.274CS..THydrogen-bonded Turntrans79.711.317800000115.2W126 V127 E137W126-G129 WeakPolarHBondContact CH2-O 3.32Å; W126-G129 VanDerWaalsContact CZ2-CA 3.43Å; W126-G129 WeakPolarHBondContact CZ2-O 3.33Å; V127-G129 PolarHBondContact O-N 3.28Å; G129-E137 WeakPolarHBondContact O-CA 3.48Å
130V88.6Confident88.2Confident33 Ų3353.7 Ų53.720%0.228%0.276CS..EExtended strand (participates in β ladder)trans-135.3152.3178.1-65.50000113.2W126 V127 Q136 E137W126-V130 WeakPolarHBondContact CA-O 3.39Å; W126-V130 VanDerWaalsContact CE3-C 3.42Å; V127-V130 PolarHBondContact N-O 3.23Å; V127-V130 VanDerWaalsContact O-CG2 3.27Å; V127-V130 WeakPolarHBondContact O-CG2 3.36Å; V127-V130 PolarHBondContact O-N 3.28Å; V130-Q136 WeakPolarHBondContact CA-O 3.36Å; V130-E137 HydrophobicContact CG1-CG 4.03Å
131W89.8Confident87.9Confident5 Ų550.8 Ų50.82%0.01927%0.269CS..EExtended strand (participates in β ladder)trans-83.5117.2167.8-76.1107.8000111P89 Y91 H122 C124 W126 C133 C134 Q135 Q136 V138 K139P89-W131 HydrophobicContact CB-CH2 4.29Å; P89-W131 HydrophobicContact CG-CH2 3.85Å; P89-W131 HydrophobicContact CG-CZ2 4.46Å; Y91-W131 WeakPolarHBondContact OH-CZ3 3.45Å; H122-W131 HydrophobicContact CB-CD2 3.68Å; H122-W131 HydrophobicContact CB-CE3 3.3Å; H122-W131 HydrophobicContact CB-CG 4.42Å; H122-W131 HydrophobicContact CB-CH2 3.84Å; H122-W131 HydrophobicContact CB-CZ2 4.2Å; H122-W131 HydrophobicContact CB-CZ3 3.37Å; H122-W131 AromaticContact CD2-CD1 3.72Å; H122-W131 AromaticContact CD2-CD2 3.41Å; H122-W131 VanDerWaalsContact CD2-CD2 3.41Å; H122-W131 AromaticContact CD2-CE2 3.14Å; H122-W131 AromaticContact CD2-CE3 3.99Å; H122-W131 AromaticContact CD2-CG 3.79Å; H122-W131 AromaticContact CD2-CZ2 3.5Å; H122-W131 VanDerWaalsContact CD2-CZ2 3.5Å; H122-W131 WeakPolarHBondContact CD2-CZ2 3.39Å; H122-W131 AromaticContact CD2-NE1 3.36Å; H122-W131 PolarHBondContact CD2-NE1 2.96Å; H122-W131 AromaticContact CE1-CD1 3.94Å; H122-W131 AromaticContact CG-CD2 3.45Å; H122-W131 VanDerWaalsContact CG-CD2 3.45Å; H122-W131 AromaticContact CG-CE2 3.71Å; H122-W131 AromaticContact CG-CE3 3.67Å; H122-W131 AromaticContact CG-CG 3.82Å; H122-W131 AromaticContact NE2-CD1 3.53Å; H122-W131 AromaticContact NE2-CE2 3.77Å; H122-W131 AromaticContact NE2-CG 3.88Å; H122-W131 AromaticContact NE2-NE1 3.46Å; H122-W131 PolarHBondContact NE2-NE1 2.92Å; C124-W131 VanDerWaalsContact O-CZ3 3.24Å; C124-W131 WeakPolarHBondContact O-CZ3 3.23Å; W126-W131 HydrophobicContact CB-CD2 4.31Å; W126-W131 HydrophobicContact CB-CE3 4.04Å; W126-W131 HydrophobicContact CB-CH2 4.23Å; W126-W131 HydrophobicContact CB-CZ2 4.42Å; W126-W131 HydrophobicContact CB-CZ3 4.02Å; W126-W131 HydrophobicContact CE3-CB 4.31Å; W126-W131 AromaticContact CE3-CD1 3.34Å; W126-W131 AromaticContact CE3-CD2 3.62Å; W126-W131 HydrophobicContact CE3-CD2 3.62Å; W126-W131 AromaticContact CE3-CE2 3.52Å; W126-W131 HydrophobicContact CE3-CE3 4.45Å; W126-W131 AromaticContact CE3-CG 3.52Å; W126-W131 HydrophobicContact CE3-CG 3.52Å; W126-W131 HydrophobicContact CE3-CZ2 4.31Å; W126-W131 AromaticContact CE3-NE1 3.31Å; W126-W131 VanDerWaalsContact CE3-NE1 3.31Å; W126-W131 AromaticContact CZ3-CD1 3.3Å; W126-W131 HydrophobicContact CZ3-CD2 4.37Å; W126-W131 AromaticContact CZ3-CG 3.88Å; W126-W131 HydrophobicContact CZ3-CG 3.88Å; W126-W131 AromaticContact CZ3-NE1 3.46Å; W131-C133 PolarHBondContact O-N 2.96Å; W131-C134 PolarHBondContact O-N 2.84Å; W131-C134 VanDerWaalsContact O-N 3.16Å; W131-Q135 WeakPolarHBondContact O-CA 3.45Å; W131-Q135 PolarHBondContact O-N 3.21Å; W131-Q136 PolarHBondContact N-O 2.89Å; W131-V138 PolarHBondContact NE1-O 3.25Å; W131-K139 VanDerWaalsContact CZ2-O 3.26Å; W131-K139 WeakPolarHBondContact CZ2-O 3.39Å; W131-K139 PolarHBondContact NE1-O 2.93Å
132L89.7Confident87.6Confident79 Ų7957.1 Ų57.141%0.41430%0.3SS..THydrogen-bonded Turntrans-61.2-19.9-177.5-65.4-178.2000114.4C124 F125 V127C124-L132 HydrophobicContact CB-CB 3.88Å; F125-L132 HydrophobicContact CB-CD1 4.28Å; F125-L132 WeakPolarHBondContact O-CG 3.48Å; F125-L132 PolarHBondContact O-N 3.44Å; F125-L132 VanDerWaalsContact O-N 3.08Å; V127-L132 HydrophobicContact CB-CD2 4.41Å; V127-L132 HydrophobicContact CB-CG 4.41Å; V127-L132 HydrophobicContact CG2-CD1 3.71Å; V127-L132 HydrophobicContact CG2-CD2 4.43Å; V127-L132 HydrophobicContact CG2-CG 3.96Å
133C89.4Confident87.3Confident39 Ų3957.2 Ų57.226%0.26430%0.303SS..THydrogen-bonded Turntrans-80.1-26.6179.749.80000114.5H122 P123 C124 W131 C144H122-C133 PolarHBondContact ND1-SG 3.43Å; P123-C133 HydrophobicContact CG-CB 3.97Å; C124-C133 HydrophobicContact CB-CB 3.74Å; W131-C133 PolarHBondContact O-N 2.96Å; C133-C144 PolarHBondContact SG-SG 3.42Å
134C88.1Confident87.2Confident44 Ų4459.6 Ų59.630%0.29732%0.319SS..THydrogen-bonded Turntrans-149.83.5-170.564.30000114.7H122 W131 Q136 C144H122-C134 PolarHBondContact CE1-SG 3.38Å; W131-C134 PolarHBondContact O-N 2.84Å; W131-C134 VanDerWaalsContact O-N 3.16Å; C134-Q136 PolarHBondContact O-N 2.84Å; C134-Q136 VanDerWaalsContact SG-CG 3.57Å; C134-C144 HydrophobicContact CB-CB 3.76Å
135Q89.9Confident87.1Confident121 Ų12162.9 Ų62.957%0.56533%0.331SS*.  trans59.920.6178.8-53.7-61.3-19.900114.9W131W131-Q135 WeakPolarHBondContact O-CA 3.45Å; W131-Q135 PolarHBondContact O-N 3.21Å
136Q86.8Confident87Confident68 Ų6866.5 Ų66.532%0.31835%0.354SS..  trans-67.8134.1172.8-75.8178.5-8.500110.8H122 W126 V130 W131 C134 A141 M142H122-Q136 PolarHBondContact CE1-OE1 3.18Å; H122-Q136 PolarHBondContact NE2-OE1 3.29Å; H122-Q136 VanDerWaalsContact NE2-OE1 3.14Å; W126-Q136 VanDerWaalsContact CZ3-O 3.29Å; W126-Q136 WeakPolarHBondContact CZ3-O 3.49Å; V130-Q136 WeakPolarHBondContact CA-O 3.36Å; W131-Q136 PolarHBondContact N-O 2.89Å; C134-Q136 PolarHBondContact O-N 2.84Å; C134-Q136 VanDerWaalsContact SG-CG 3.57Å; Q136-A141 HydrophobicContact CB-CB 4.21Å; Q136-M142 PolarHBondContact OE1-O 3.12Å
137E87.6Confident86.6Confident159 Ų15966.2 Ų66.274%0.74335%0.354SS*.SBendtrans-93.44.6-174.5-61.4-177.8167.100114.3W126 G129 V130W126-E137 VanDerWaalsContact CH2-C 3.44Å; W126-E137 WeakPolarHBondContact CH2-O 3.47Å; G129-E137 WeakPolarHBondContact O-CA 3.48Å; V130-E137 HydrophobicContact CG1-CG 4.03Å
138V84.6Confident85.8Confident94 Ų9473.1 Ų73.157%0.5739%0.385SS*.  trans-113.7120.5177.1179.20000109.9W126 W131 Q140 A141W126-V138 VanDerWaalsContact CZ3-C 3.48Å; W131-V138 PolarHBondContact NE1-O 3.25Å; V138-Q140 PolarHBondContact O-N 2.91Å; V138-A141 HydrophobicContact CB-CB 4.09Å; V138-A141 WeakPolarHBondContact O-CB 3.26Å; V138-A141 PolarHBondContact O-N 2.8Å
139K83.6Confident84.6Confident50 Ų5072.9 Ų72.922%0.21739%0.391CS..THydrogen-bonded Turntrans-61.3-30.4-174.9-167.7175.3-176.1-177.70113.4Q15 Q16 W126 W131Q15-K139 PolarHBondContact O-NZ 3.26Å; Q16-K139 PolarHBondContact O-NZ 3.36Å; Q16-K139 VanDerWaalsContact O-NZ 3.07Å; W126-K139 HydrophobicContact CD2-CB 4.04Å; W126-K139 HydrophobicContact CD2-CG 3.82Å; W126-K139 HydrophobicContact CE3-CB 4.3Å; W126-K139 HydrophobicContact CE3-CG 4.36Å; W126-K139 HydrophobicContact CG-CD 4.46Å; W126-K139 HydrophobicContact CG-CG 4.04Å; W126-K139 VanDerWaalsContact CH2-CA 3.46Å; W126-K139 HydrophobicContact CH2-CB 3.88Å; W126-K139 HydrophobicContact CZ2-CB 3.59Å; W126-K139 HydrophobicContact CZ2-CG 4.19Å; W126-K139 VanDerWaalsContact CZ3-CA 3.48Å; W126-K139 HydrophobicContact CZ3-CB 4.23Å; W131-K139 VanDerWaalsContact CZ2-O 3.26Å; W131-K139 WeakPolarHBondContact CZ2-O 3.39Å; W131-K139 PolarHBondContact NE1-O 2.93Å
140Q84Confident82.7Confident152 Ų15275 Ų7571%0.7140%0.403SS*.THydrogen-bonded Turntrans-97.512.6176.7-66.8-174.2-16.900113D86 V138D86-Q140 PolarHBondContact O-NE2 2.95Å; V138-Q140 PolarHBondContact O-N 2.91Å
141A84.5Confident80.6Confident27 Ų2777 Ų7722%0.22342%0.424CS..PPolyproline II helixtrans-60149177.300000111.8H122 Q136 V138 G143H122-A141 PolarHBondContact NE2-O 2.85Å; Q136-A141 HydrophobicContact CB-CB 4.21Å; V138-A141 HydrophobicContact CB-CB 4.09Å; V138-A141 WeakPolarHBondContact O-CB 3.26Å; V138-A141 PolarHBondContact O-N 2.8Å; A141-G143 PolarHBondContact O-N 3.25Å
142M84.8Confident78.3Confident139 Ų13986 Ų8669%0.68546%0.463SS*.PPolyproline II helixtrans-57.4132.1176.2-173.9-179.1-70.200110.6K120 H122 Q136K120-M142 HydrophobicContact CB-CG 4.28Å; K120-M142 HydrophobicContact CD-CG 4.21Å; K120-M142 HydrophobicContact CD-SD 4.11Å; H122-M142 PolarHBondContact CE1-O 3.18Å; H122-M142 PolarHBondContact NE2-O 2.88Å; Q136-M142 PolarHBondContact OE1-O 3.12Å
143G88.6Confident75.9Confident7 Ų789.9 Ų89.97%0.07248%0.484CS..PPolyproline II helixtrans-53.4151.2-178.700000115.2K120 Y121 H122 A141K120-G143 WeakPolarHBondContact CB-O 3.38Å; K120-G143 VanDerWaalsContact CD-O 3.28Å; K120-G143 WeakPolarHBondContact CD-O 3.4Å; Y121-G143 CarbonylContact O-C 3.52Å; Y121-G143 WeakPolarHBondContact O-CA 3.39Å; H122-G143 VanDerWaalsContact CE1-CA 3.49Å; H122-G143 WeakPolarHBondContact CE1-CA 3.23Å; H122-G143 WeakPolarHBondContact NE2-CA 3.46Å; A141-G143 PolarHBondContact O-N 3.25Å
144C88.4Confident73.2Confident59 Ų5991.1 Ų91.140%0.39950%0.503SS..SBendtrans-88.1-10.5175.970.30000114.5Y121 H122 P123 C133 C134Y121-C144 PolarHBondContact O-N 2.89Å; H122-C144 PolarHBondContact CE1-N 2.86Å; H122-C144 PolarHBondContact ND1-N 2.94Å; P123-C144 VanDerWaalsContact CD-SG 3.54Å; C133-C144 PolarHBondContact SG-SG 3.42Å; C134-C144 HydrophobicContact CB-CB 3.76Å
145K90.5Very high70.6Confident85 Ų8599.4 Ų99.437%0.3754%0.535SS..EExtended strand (participates in β ladder)trans-118.8133.4-180-172.2173.1174.5-165.10111.5K120 Y121 P123K120-K145 CarbonylContact C-O 3.54Å; K120-K145 WeakPolarHBondContact CA-O 3.28Å; K120-K145 WeakPolarHBondContact CB-O 3.43Å; Y121-K145 HydrophobicContact CD1-CB 4.45Å; Y121-K145 WeakPolarHBondContact CD1-O 3.5Å; Y121-K145 HydrophobicContact CE1-CB 4.17Å; Y121-K145 HydrophobicContact CE1-CD 4.12Å; Y121-K145 HydrophobicContact CE1-CG 4Å; Y121-K145 HydrophobicContact CE2-CD 4.42Å; Y121-K145 PolarHBondContact N-O 2.93Å; Y121-K145 PolarHBondContact O-N 3.45Å; Y121-K145 WeakPolarHBondContact OH-CD 3.43Å; Y121-K145 WeakPolarHBondContact OH-CE 3.46Å; Y121-K145 PolarHBondContact OH-NZ 2.79Å; Y121-K145 VanDerWaalsContact OH-NZ 3.13Å; P123-K145 HydrophobicContact CB-CD 4.16Å; P123-K145 HydrophobicContact CG-CB 4.31Å; P123-K145 HydrophobicContact CG-CD 4.26Å
146V88.8Confident68.1Low80 Ų80103.5 Ų103.549%0.48555%0.551SS.*EExtended strand (participates in β ladder)trans-72.3135.8179.1-179.60000110.5K120K120-V146 HydrophobicContact CG-CG2 4.34Å
147L81.5Confident65.4Low18 Ų18106 Ų1069%0.09458%0.576CS.*  trans-75.7121.4172.7-155.984.5000108.8E65 Q119 Y121 S149 S150E65-L147 HydrophobicContact CG-CD1 3.82Å; Q119-L147 PolarHBondContact O-N 3.41Å; Y121-L147 HydrophobicContact CD1-CD1 3.68Å; Y121-L147 HydrophobicContact CE1-CD1 3.97Å; Y121-L147 HydrophobicContact CG-CD1 4.46Å; L147-S149 PolarHBondContact O-N 3.16Å; L147-S150 PolarHBondContact O-N 3.28Å
148E67.7Low62.8Low163 Ų163104.1 Ų104.176%0.76258%0.58SS**G310 helixtrans-62-17.2-172.5-67.5-174.5170.500113.9S150 A151E148-S150 PolarHBondContact O-N 3.21Å; E148-A151 WeakPolarHBondContact O-CB 3.11Å; E148-A151 PolarHBondContact O-N 3.31Å
149S56.6Low60.7Low95 Ų95105.3 Ų105.366%0.66459%0.59SS**G310 helixtrans-65.5-23.8173-500000113.5L147L147-S149 PolarHBondContact O-N 3.16Å
150S44.1Very low58.2Low57 Ų57107.3 Ų107.340%0.39961%0.61SS.*G310 helixtrans-84.6-8.3176.3-57.90000113.4L147 E148 K152L147-S150 PolarHBondContact O-N 3.28Å; E148-S150 PolarHBondContact O-N 3.21Å; S150-K152 VanDerWaalsContact C-N 3.29Å; S150-K152 PolarHBondContact O-N 3.12Å
151A43.2Very low56Low76 Ų76110.4 Ų110.463%0.62862%0.615SS**G310 helixtrans-82.32.6-176.200000114.5E148E148-A151 WeakPolarHBondContact O-CB 3.11Å; E148-A151 PolarHBondContact O-N 3.31Å
152K42.4Very low53.5Low193 Ų193120 Ų12084%0.83965%0.646SS**G310 helixtrans-83.6-7.3178.6-77-168.5177.2-177.70115S150S150-K152 VanDerWaalsContact C-N 3.29Å; S150-K152 PolarHBondContact O-N 3.12Å
153N39.7Very low51.1Low161 Ų161121.1 Ų121.186%0.86165%0.651SS**SBendtrans-125.194174.8-76.4-8.6000111
154G32.5Very low48.3Very low65 Ų65126.6 Ų126.667%0.6769%0.688SS**SBendtrans129.698.115900000116.7
155F33.2Very low45.6Very low218 Ų218133.5 Ų133.596%0.95671%0.706SS**  trans41.7127.7151.1-74.7-89.3000122.9
156K37.3Very low42.8Very low207 Ų207138.4 Ų138.490%0.973%0.727SS**  trans-69148.6175.1-61.7173.5176.7175.70113.2
157S29.5Very low40.7Very low122 Ų122140.3 Ų140.385%0.85374%0.741SS**  trans-161117.8136.856.90000112
158S32.9Very low38.5Very low118 Ų118147.3 Ų147.383%0.82578%0.778SS**  trans-80.2162.3167.9-74.90000111.3
159P40.8Very low37.2Very low120 Ų120145.1 Ų145.178%0.77978%0.778SS**  -138.91368822.7-1.1000113.8
160S32Very low36.6Very low91 Ų91146.2 Ų146.264%0.63678%0.783SS**  55.4127.891.9154.60000113.3
161R38Very low36.2Very low217 Ų217149.9 Ų149.982%0.81980%0.803SS**  cis-169.2160.522.5-99.8159.8-163.5-171.33.1104.3
162R31.3Very low36.1Very low230 Ų230151.4 Ų151.487%0.86881%0.807SS**  -177.3152.354.5-136.5169.5-160.51783.9109.4
163M34.4Very low35.6Very low161 Ų161147.7 Ų147.779%0.79380%0.8SS**  trans-87.8162.1-176.7-56.7-145.675.400114.2
164S30Very low35.2Very low122 Ų122148.1 Ų148.185%0.85380%0.797SS**  -165.9156.4112.893.90000112.6
165R32Very low35Very low205 Ų205153.6 Ų153.677%0.77481%0.805SS**  trans-125.3141.2-173-84.5176.6159.6179.9-4.5110
166K31.7Very low35.1Very low187 Ų187152.6 Ų152.681%0.81380%0.8SS**  trans63169.8139.4-75.4-171.6177.5-170.30119.8
167P44.1Very low35.4Very low120 Ų120149 Ų14978%0.77980%0.798SS**  cis-137.1178.1-22.128.1-4.4000116.1
168L36Very low35.5Very low166 Ų166146.9 Ų146.987%0.86980%0.795SS**  trans-68.6173.7164.6-74.7158.1000113.1
169P40.4Very low35.7Very low116 Ų116152 Ų15275%0.75380%0.797SS**  cis-151.7-146.237.144.5-20.1000114.2
170P43.3Very low35.7Very low119 Ų119152 Ų15277%0.77380%0.797SS**  cis-130.1-177.7-25.634-11.9000115.9
171T35.3Very low36.1Very low134 Ų134155.1 Ų155.182%0.82281%0.805SS**  trans-75.4166.9179.6-6.10000115.8
172P41.4Very low36.6Very low108 Ų108149.8 Ų149.870%0.70180%0.799SS**  -158.4166.192.640-18.3000120.5
173T30.8Very low37.4Very low115 Ų115145 Ų14571%0.70680%0.797SS**  trans74.8122.9142.3460000126.2
174E32.7Very low37.9Very low169 Ų169140.3 Ų140.379%0.7979%0.791SS**  trans44146131.4-69.9175.6167.400121.4
175E28.7Very low38.7Very low181 Ų181140.4 Ų140.485%0.84679%0.789SS**  cis-165.216626.5-126.6174-175.800111
176K35.4Very low39.3Very low197 Ų197136.6 Ų136.686%0.85779%0.79SS**  trans-81.5175.2175.8-91.7178.9-178.5174.60111.9
177P42Very low39.7Very low130 Ų130136 Ų13684%0.84479%0.791SS**  cis-154-178.93540.3-16.4000119.2
178G32Very low39.5Very low78 Ų78135.9 Ų135.980%0.80479%0.789SS**  trans152.7109.5156.500000115.6
179R38.1Very low39.6Very low226 Ų226133.9 Ų133.985%0.85379%0.786SS**  trans-106.1146.5-175.5-165.6-169.2-150.9-172.17.4111.1
180P39.4Very low39.5Very low121 Ų121132.8 Ų132.879%0.78679%0.787SS**  trans-106.6152.7149.1-3.423.5000113.2
181L41.2Very low39Very low155 Ų155135.9 Ų135.981%0.81279%0.791SS**PPolyproline II helixtrans-71.4163.2-169.5-73.5158000115
182P48.2Very low39.2Very low105 Ų105135.2 Ų135.268%0.68279%0.789SS**PPolyproline II helixtrans-78.9149-179.76.310.2000112.6
183P48.4Very low39.5Very low129 Ų129134.4 Ų134.484%0.83879%0.792SS**PPolyproline II helixtrans-67.8144.1166.6-11.826.6000111.5
184G45.2Very low41.1Very low63 Ų63132.8 Ų132.865%0.64979%0.785SS**PPolyproline II helixtrans-67.2166176.800000113.8
185P46.5Very low43.3Very low125 Ų125127.6 Ų127.681%0.81276%0.762SS**PPolyproline II helixtrans-66137.8-176.626.5-31.7000111.1
186P44.9Very low45.8Very low124 Ų124121.2 Ų121.281%0.80574%0.736SS**PPolyproline II helixtrans-64145170.38.2-3.9000111.1
187E38.8Very low48.1Very low176 Ų176111.8 Ų111.882%0.82270%0.695SS**PPolyproline II helixtrans-51152.8167.7-94.3175.4146.500111.9
188P39.8Very low50Low116 Ų116107.1 Ų107.175%0.75366%0.663SS**PPolyproline II helixtrans-58.7135.5175.3-3.413.2000109.6A190P188-A190 PolarHBondContact O-N 3.32Å
189P39.7Very low52.2Low124 Ų124103.4 Ų103.481%0.80563%0.625SS**PPolyproline II helixtrans-58.8137.2173.423.3-30.5000109.5Q191P189-Q191 PolarHBondContact O-N 3.06Å
190A36.7Very low53.3Low93 Ų9394.8 Ų94.877%0.76960%0.595SS**PPolyproline II helixtrans-47135.6168.900000109.7P188P188-A190 PolarHBondContact O-N 3.32Å
191Q34.1Very low54.2Low184 Ų18491.1 Ų91.186%0.8657%0.565SS**PPolyproline II helixtrans-49.2129.7176-66.91800.400109P189 A193P189-Q191 PolarHBondContact O-N 3.06Å; Q191-A193 PolarHBondContact O-N 2.8Å
192P39.8Very low55.5Low120 Ų12089.1 Ų89.178%0.77956%0.556SS**PPolyproline II helixtrans-58.3137.4173.823.9-30.7000108.1S194P192-S194 PolarHBondContact O-N 2.73Å
193A46.3Very low56.9Low91 Ų9184.5 Ų84.575%0.75253%0.525SS*.  trans-45.6114178.700000109.6Q191 I195Q191-A193 PolarHBondContact O-N 2.8Å; A193-I195 PolarHBondContact O-N 2.93Å; A193-I195 VanDerWaalsContact O-N 3.15Å
194S64.5Low58.3Low82 Ų8281.9 Ų81.957%0.57351%0.514SS*.PPolyproline II helixtrans-62.8116.1178.657.50000108.3P192P192-S194 PolarHBondContact O-N 2.73Å
195I79.1Confident59.8Low59 Ų5981.6 Ų81.630%0.30350%0.501SS..EExtended strand (participates in β ladder)trans-83.7120.5179.3-57.7169.1000108.1A193 V197 I221 R224 E249A193-I195 PolarHBondContact O-N 2.93Å; A193-I195 VanDerWaalsContact O-N 3.15Å; I195-V197 HydrophobicContact CG2-CG1 4.44Å; I195-I221 WeakPolarHBondContact O-CB 3.42Å; I195-I221 PolarHBondContact O-N 3.03Å; I195-R224 VanDerWaalsContact CD1-NH2 3.31Å; I195-E249 HydrophobicContact CG2-CG 4.13Å
196T82.5Confident60.6Low47 Ų4777.6 Ų77.629%0.28847%0.472SS..EExtended strand (participates in β ladder)trans-88.4132.8173.2-50.80000109.4E218 Y219 A250T196-E218 HydrophobicContact CG2-CB 3.99Å; T196-E218 HydrophobicContact CG2-CG 4.14Å; T196-Y219 CarbonylContact C-O 3.56Å; T196-Y219 WeakPolarHBondContact CA-O 3.42Å; T196-A250 HydrophobicContact CG2-CB 4.34Å; T196-A250 WeakPolarHBondContact O-CB 3.4Å; T196-A250 PolarHBondContact O-N 3.12Å
197V82.7Confident61.7Low0 Ų073 Ų730%044%0.442CS..EExtended strand (participates in β ladder)trans-120153.3175.7-59.90000109.6I195 E218 Y219 I221 W230 I242 V247 V248 E249I195-V197 HydrophobicContact CG2-CG1 4.44Å; V197-E218 CarbonylContact O-C 3.48Å; V197-E218 WeakPolarHBondContact O-CA 3.23Å; V197-Y219 PolarHBondContact N-O 2.67Å; V197-Y219 PolarHBondContact O-N 2.6Å; V197-I221 HydrophobicContact CB-CD1 4.45Å; V197-I221 HydrophobicContact CB-CG1 4.42Å; V197-I221 HydrophobicContact CG1-CD1 3.98Å; V197-I221 HydrophobicContact CG1-CG1 3.56Å; V197-I221 HydrophobicContact CG2-CD1 3.58Å; V197-I221 HydrophobicContact CG2-CG1 3.98Å; V197-W230 HydrophobicContact CG1-CZ3 4.23Å; V197-I242 HydrophobicContact CG2-CD1 4.37Å; V197-V247 HydrophobicContact CB-CB 3.92Å; V197-V247 HydrophobicContact CB-CG2 4.16Å; V197-V247 HydrophobicContact CG1-CG2 4.42Å; V197-V247 HydrophobicContact CG2-CB 3.73Å; V197-V247 HydrophobicContact CG2-CG1 4.06Å; V197-V247 HydrophobicContact CG2-CG2 3.92Å; V197-V248 CarbonylContact C-O 3.56Å; V197-V248 WeakPolarHBondContact CA-O 3.39Å; V197-V248 VanDerWaalsContact CB-O 3.22Å; V197-V248 WeakPolarHBondContact CB-O 3.37Å; V197-E249 HydrophobicContact CG1-CG 4.48Å
198V81.6Confident63.4Low31 Ų3171.3 Ų71.319%0.18845%0.445CS..EExtended strand (participates in β ladder)trans-109.3135.4172.8179.30000108.1E200 E217 E218 V247 V248 A250V198-E200 PolarHBondContact O-N 2.88Å; V198-E217 WeakPolarHBondContact CA-O 3.31Å; V198-E218 HydrophobicContact CG2-CG 3.91Å; V198-V247 CarbonylContact O-C 3.55Å; V198-V247 VanDerWaalsContact O-CA 3.28Å; V198-V247 WeakPolarHBondContact O-CA 3.22Å; V198-V248 HydrophobicContact CB-CG2 4.41Å; V198-V248 PolarHBondContact N-O 2.97Å; V198-V248 PolarHBondContact O-N 2.85Å; V198-A250 HydrophobicContact CG2-CB 4.02Å
199A79.3Confident65.2Low0 Ų071.6 Ų71.60%044%0.437CS..EExtended strand (participates in β ladder)trans-72.8121.8173.900000111.4L213 R214 D216 E217 Y219 Y246 V247A199-L213 HydrophobicContact CB-CB 3.9Å; A199-L213 HydrophobicContact CB-CD1 4.5Å; A199-L213 HydrophobicContact CB-CD2 4.24Å; A199-L213 HydrophobicContact CB-CG 4.46Å; A199-R214 VanDerWaalsContact CB-O 3.31Å; A199-R214 WeakPolarHBondContact CB-O 3.46Å; A199-D216 PolarHBondContact O-N 3.27Å; A199-E217 PolarHBondContact N-O 3.07Å; A199-Y219 HydrophobicContact CB-CD2 4.25Å; A199-Y219 HydrophobicContact CB-CE2 3.79Å; A199-Y246 WeakPolarHBondContact CA-O 3.13Å; A199-V247 HydrophobicContact CB-CG1 4.35Å
200E60.1Low67.3Low45 Ų4565.8 Ų65.821%0.2140%0.399CS..SBendtrans-78.9-24.5173.8-73.1-160.3143.300112.5V198 K215 Y246 V248V198-E200 PolarHBondContact O-N 2.88Å; E200-K215 WeakPolarHBondContact O-CD 3.34Å; E200-K215 WeakPolarHBondContact O-CE 3.39Å; E200-K215 WeakPolarHBondContact O-CG 3.17Å; E200-Y246 PolarHBondContact N-O 3.37Å; E200-V248 VanDerWaalsContact CD-CG1 3.42Å; E200-V248 HydrophobicContact CG-CB 4.33Å; E200-V248 HydrophobicContact CG-CG1 3.71Å; E200-V248 HydrophobicContact CG-CG2 3.78Å; E200-V248 WeakPolarHBondContact OE1-CG1 3.5Å
201Y59.6Low69.7Low44 Ų4461.4 Ų61.417%0.17336%0.363CS..SBendtrans-137152.4-174.9-49.2-76.8000111Y246 A359 P361Y201-Y246 HydrophobicContact CD2-CD1 4.42Å; Y201-Y246 HydrophobicContact CD2-CG 4.42Å; Y201-A359 PolarHBondContact OH-O 2.97Å; Y201-P361 HydrophobicContact CD1-CB 3.75Å; Y201-P361 HydrophobicContact CD1-CG 4.08Å; Y201-P361 HydrophobicContact CD2-CB 4.33Å; Y201-P361 HydrophobicContact CE1-CB 3.67Å; Y201-P361 HydrophobicContact CE1-CG 4.05Å; Y201-P361 HydrophobicContact CE2-CB 4.3Å; Y201-P361 HydrophobicContact CG-CB 4.09Å
202D68.2Low72.4Confident114 Ų11456.2 Ų56.261%0.6134%0.338SS*.  trans-67.6134.6167.3-62.4-41.4000109.7L213 R214 K215D202-L213 CarbonylContact C-O 3.55Å; D202-L213 WeakPolarHBondContact CA-O 3.48Å; D202-R214 WeakPolarHBondContact OD1-CA 2.81Å; D202-K215 WeakPolarHBondContact OD1-CB 3.4Å; D202-K215 PolarHBondContact OD1-N 3.47Å
203Y76.8Confident74.5Confident7 Ų750.6 Ų50.63%0.02730%0.302CS..BIsolated β-bridgetrans-128.9115.1173.2176.9-104.1000109.4M206 D210 L211 E212 L213 W229 P243 Y246Y203-M206 HydrophobicContact CE2-CE 4.05Å; Y203-M206 HydrophobicContact CE2-CG 4.17Å; Y203-M206 HydrophobicContact CE2-SD 4.28Å; Y203-M206 WeakPolarHBondContact OH-CB 3.32Å; Y203-M206 WeakPolarHBondContact OH-CG 3.46Å; Y203-M206 PolarHBondContact OH-N 3.02Å; Y203-D210 HydrophobicContact CE1-CB 3.97Å; Y203-D210 PolarHBondContact OH-OD2 2.83Å; Y203-L211 WeakPolarHBondContact CD1-O 3.47Å; Y203-E212 WeakPolarHBondContact O-CA 3.47Å; Y203-L213 PolarHBondContact N-O 2.81Å; Y203-L213 PolarHBondContact O-N 3.39Å; Y203-W229 HydrophobicContact CE1-CZ3 4.37Å; Y203-W229 HydrophobicContact CE2-CH2 4.25Å; Y203-W229 AromaticContact CZ-CH2 3.82Å; Y203-W229 VanDerWaalsContact OH-CH2 3.25Å; Y203-W229 WeakPolarHBondContact OH-CH2 3.37Å; Y203-P243 HydrophobicContact CD1-CG 4.35Å; Y203-P243 HydrophobicContact CD2-CG 3.7Å; Y203-P243 HydrophobicContact CE1-CG 4.35Å; Y203-P243 HydrophobicContact CE2-CG 3.71Å; Y203-P243 HydrophobicContact CG-CG 4.05Å; Y203-Y246 HydrophobicContact CD2-CD1 4.34Å; Y203-Y246 HydrophobicContact CD2-CE1 4.2Å; Y203-Y246 HydrophobicContact CG-CD1 4.46Å
204A77.3Confident76.3Confident75 Ų7551.3 Ų51.362%0.6229%0.285SS*.  trans-79.9129.4169.700000109.3M206A204-M206 PolarHBondContact O-N 3.31Å
205P77.3Confident76.8Confident56 Ų5651.9 Ų51.936%0.36428%0.277SS..  trans-52.3121.4176-28.236.2000111.7D210 E212P205-D210 HydrophobicContact CB-CB 3.94Å; P205-E212 HydrophobicContact CG-CB 3.77Å
206M64Low76.4Confident42 Ų4254.4 Ų54.421%0.20729%0.291CS..SBendtrans-86.6-29.1175.8-65.9-178177.800111.4Y203 A204 D210 T364 W398Y203-M206 HydrophobicContact CE2-CE 4.05Å; Y203-M206 HydrophobicContact CE2-CG 4.17Å; Y203-M206 HydrophobicContact CE2-SD 4.28Å; Y203-M206 WeakPolarHBondContact OH-CB 3.32Å; Y203-M206 WeakPolarHBondContact OH-CG 3.46Å; Y203-M206 PolarHBondContact OH-N 3.02Å; A204-M206 PolarHBondContact O-N 3.31Å; M206-D210 WeakPolarHBondContact CA-OD2 3.48Å; M206-D210 WeakPolarHBondContact CB-OD2 3.26Å; M206-D210 PolarHBondContact N-OD2 3.48Å; M206-T364 HydrophobicContact CE-CG2 4.07Å; M206-W398 HydrophobicContact SD-CH2 4.15Å; M206-W398 HydrophobicContact SD-CZ3 4.42Å
207T67.9Low76.5Confident28 Ų2854 Ų5417%0.17229%0.286CS..SBendtrans-123.6160.4174.688.10000111.7Q209 D210 V371T207-Q209 PolarHBondContact O-N 3Å; T207-Q209 VanDerWaalsContact O-N 3.11Å; T207-Q209 PolarHBondContact OG1-N 3.4Å; T207-Q209 VanDerWaalsContact OG1-N 3.12Å; T207-D210 PolarHBondContact N-OD2 2.97Å; T207-D210 WeakPolarHBondContact O-CB 3.47Å; T207-D210 PolarHBondContact O-N 3.36Å; T207-D210 VanDerWaalsContact OG1-CG 3.26Å; T207-D210 PolarHBondContact OG1-N 2.8Å; T207-D210 PolarHBondContact OG1-OD1 2.85Å; T207-V371 HydrophobicContact CG2-CG2 4.35Å
208P74.2Confident76.7Confident139 Ų13960 Ų6090%0.90331%0.314SS*.THydrogen-bonded Turntrans-61.6-16.2172.5-21.933.3000114.2D210P208-D210 VanDerWaalsContact C-N 3.34Å
209Q76.7Confident77.1Confident122 Ų12258.7 Ų58.757%0.5731%0.306SS*.THydrogen-bonded Turntrans-87.9-9.7178.4-57.5178.5100111.9T207 G240 Y241T207-Q209 PolarHBondContact O-N 3Å; T207-Q209 VanDerWaalsContact O-N 3.11Å; T207-Q209 PolarHBondContact OG1-N 3.4Å; T207-Q209 VanDerWaalsContact OG1-N 3.12Å; Q209-G240 CarbonylContact O-C 3.59Å; Q209-G240 VanDerWaalsContact O-CA 3.23Å; Q209-G240 WeakPolarHBondContact O-CA 3.5Å; Q209-Y241 HydrophobicContact CB-CD2 4.27Å; Q209-Y241 PolarHBondContact O-N 3.48Å
210D84Confident77.7Confident3 Ų360.9 Ų60.92%0.01632%0.319CS..BIsolated β-bridgetrans-86.3149.7-177.8-60-0.3000111.5Y203 P205 M206 T207 P208 Y241Y203-D210 HydrophobicContact CE1-CB 3.97Å; Y203-D210 PolarHBondContact OH-OD2 2.83Å; P205-D210 HydrophobicContact CB-CB 3.94Å; M206-D210 WeakPolarHBondContact CA-OD2 3.48Å; M206-D210 WeakPolarHBondContact CB-OD2 3.26Å; M206-D210 PolarHBondContact N-OD2 3.48Å; T207-D210 PolarHBondContact N-OD2 2.97Å; T207-D210 WeakPolarHBondContact O-CB 3.47Å; T207-D210 PolarHBondContact O-N 3.36Å; T207-D210 VanDerWaalsContact OG1-CG 3.26Å; T207-D210 PolarHBondContact OG1-N 2.8Å; T207-D210 PolarHBondContact OG1-OD1 2.85Å; P208-D210 VanDerWaalsContact C-N 3.34Å; D210-Y241 VanDerWaalsContact CA-O 3.31Å; D210-Y241 WeakPolarHBondContact CA-O 3.46Å
211L88.9Confident79.1Confident0 Ų059.4 Ų59.40%031%0.313CS..PPolyproline II helixtrans-103137.3174-176.466.7000109.8Y203 L213 Y219 A232 D234 K238 Y241 I242Y203-L211 WeakPolarHBondContact CD1-O 3.47Å; L211-L213 PolarHBondContact O-N 2.65Å; L211-Y219 HydrophobicContact CD2-CD1 3.8Å; L211-Y219 HydrophobicContact CD2-CE1 4.05Å; L211-Y219 HydrophobicContact CG-CE1 4.35Å; L211-A232 HydrophobicContact CD2-CB 4.24Å; L211-D234 HydrophobicContact CD1-CB 4.26Å; L211-D234 HydrophobicContact CD2-CB 4.2Å; L211-K238 HydrophobicContact CD1-CB 4Å; L211-K238 HydrophobicContact CD1-CD 3.81Å; L211-K238 HydrophobicContact CD1-CG 3.83Å; L211-Y241 PolarHBondContact N-O 3.49Å; L211-I242 HydrophobicContact CB-CG2 3.68Å; L211-I242 HydrophobicContact CD2-CG2 4.09Å; L211-I242 HydrophobicContact CG-CG2 4.23Å
212E88.8Confident80.4Confident75 Ų7560 Ų6035%0.3532%0.319SS..PPolyproline II helixtrans-68.3126.9177.5-176.5-173.6163.300109.1Y203 P205 R214 Y219Y203-E212 WeakPolarHBondContact O-CA 3.47Å; P205-E212 HydrophobicContact CG-CB 3.77Å; E212-R214 HydrophobicContact CG-CG 4.47Å; E212-R214 IonicContact OE1-CZ 2.95Å; E212-R214 IonicContact OE1-NE 2.67Å; E212-R214 PolarHBondContact OE1-NE 3.13Å; E212-R214 IonicContact OE1-NH2 3.15Å; E212-R214 PolarHBondContact OE1-NH2 3.4Å; E212-R214 IonicContact OE2-NH2 2.57Å; E212-Y219 WeakPolarHBondContact O-CE1 3.2Å; E212-Y219 PolarHBondContact O-OH 3.42Å
213L85.1Confident81.1Confident2 Ų258.6 Ų58.61%0.0131%0.309CS..BIsolated β-bridgetrans-96.2133166.5-57.4173.4000109.2A199 D202 Y203 L211 Y219 I242 Y246 V247A199-L213 HydrophobicContact CB-CB 3.9Å; A199-L213 HydrophobicContact CB-CD1 4.5Å; A199-L213 HydrophobicContact CB-CD2 4.24Å; A199-L213 HydrophobicContact CB-CG 4.46Å; D202-L213 CarbonylContact C-O 3.55Å; D202-L213 WeakPolarHBondContact CA-O 3.48Å; Y203-L213 PolarHBondContact N-O 2.81Å; Y203-L213 PolarHBondContact O-N 3.39Å; L211-L213 PolarHBondContact O-N 2.65Å; L213-Y219 VanDerWaalsContact CA-OH 3.28Å; L213-Y219 WeakPolarHBondContact CA-OH 3.37Å; L213-Y219 HydrophobicContact CD2-CD1 4.01Å; L213-Y219 HydrophobicContact CD2-CD2 3.71Å; L213-Y219 HydrophobicContact CD2-CE1 3.83Å; L213-Y219 HydrophobicContact CD2-CE2 3.55Å; L213-Y219 HydrophobicContact CD2-CG 3.96Å; L213-I242 HydrophobicContact CD1-CB 4.15Å; L213-I242 HydrophobicContact CD1-CG2 4.5Å; L213-I242 HydrophobicContact CD2-CB 3.96Å; L213-I242 HydrophobicContact CD2-CD1 4.06Å; L213-I242 HydrophobicContact CD2-CG2 3.56Å; L213-I242 HydrophobicContact CG-CB 4.21Å; L213-I242 HydrophobicContact CG-CG2 4.01Å; L213-Y246 VanDerWaalsContact CD1-CB 3.43Å; L213-Y246 HydrophobicContact CD1-CD1 4.39Å; L213-Y246 HydrophobicContact CD1-CG 4.33Å; L213-V247 HydrophobicContact CD1-CG1 3.65Å; L213-V247 HydrophobicContact CD2-CG1 3.91Å; L213-V247 HydrophobicContact CG-CG1 4.45Å
214R83.8Confident81.3Confident107 Ų10763.2 Ų63.240%0.40433%0.326SS..  trans-113.2128.5167.5-69.9-178.7-177.8168.66.1107.7A199 D202 E212 D216 E217 Y219A199-R214 VanDerWaalsContact CB-O 3.31Å; A199-R214 WeakPolarHBondContact CB-O 3.46Å; D202-R214 WeakPolarHBondContact OD1-CA 2.81Å; E212-R214 HydrophobicContact CG-CG 4.47Å; E212-R214 IonicContact OE1-CZ 2.95Å; E212-R214 IonicContact OE1-NE 2.67Å; E212-R214 PolarHBondContact OE1-NE 3.13Å; E212-R214 IonicContact OE1-NH2 3.15Å; E212-R214 PolarHBondContact OE1-NH2 3.4Å; E212-R214 IonicContact OE2-NH2 2.57Å; R214-D216 PolarHBondContact O-N 3.17Å; R214-E217 HydrophobicContact CB-CB 4.27Å; R214-E217 HydrophobicContact CB-CG 3.74Å; R214-E217 VanDerWaalsContact O-CB 3.31Å; R214-E217 WeakPolarHBondContact O-CB 3.43Å; R214-E217 PolarHBondContact O-N 2.83Å; R214-Y219 PolarHBondContact N-OH 2.8Å
215K74.5Confident80.7Confident93 Ų9363.8 Ų63.840%0.40433%0.325SS..THydrogen-bonded Turntrans-49.8136.9179.7-179.1175.4179.6-1710110.2E200 D202 E217E200-K215 WeakPolarHBondContact O-CD 3.34Å; E200-K215 WeakPolarHBondContact O-CE 3.39Å; E200-K215 WeakPolarHBondContact O-CG 3.17Å; D202-K215 WeakPolarHBondContact OD1-CB 3.4Å; D202-K215 PolarHBondContact OD1-N 3.47Å; K215-E217 PolarHBondContact O-N 2.92Å
216D71.1Confident80.1Confident112 Ų11262.9 Ų62.960%0.59932%0.317SS*.THydrogen-bonded Turntrans67.54.7-178.6-48.8-42.1000115A199 R214A199-D216 PolarHBondContact O-N 3.27Å; R214-D216 PolarHBondContact O-N 3.17Å
217E84.1Confident79.7Confident39 Ų3965.4 Ų65.418%0.18234%0.337CS..  trans-85.1148.4171.8-65.1-159.1168.400112.7V198 A199 R214 K215 Y219 K235V198-E217 WeakPolarHBondContact CA-O 3.31Å; A199-E217 PolarHBondContact N-O 3.07Å; R214-E217 HydrophobicContact CB-CB 4.27Å; R214-E217 HydrophobicContact CB-CG 3.74Å; R214-E217 VanDerWaalsContact O-CB 3.31Å; R214-E217 WeakPolarHBondContact O-CB 3.43Å; R214-E217 PolarHBondContact O-N 2.83Å; K215-E217 PolarHBondContact O-N 2.92Å; E217-Y219 HydrophobicContact CB-CE2 3.79Å; E217-Y219 VanDerWaalsContact O-CD2 3.32Å; E217-Y219 WeakPolarHBondContact O-CD2 3.03Å; E217-Y219 WeakPolarHBondContact O-CE2 3.25Å; E217-K235 IonicContact OE1-NZ 3.71Å; E217-K235 PolarHBondContact OE1-NZ 3.25Å; E217-K235 VanDerWaalsContact OE2-CE 3.28Å; E217-K235 WeakPolarHBondContact OE2-CE 3.31Å; E217-K235 IonicContact OE2-NZ 2.64Å; E217-K235 PolarHBondContact OE2-NZ 2.93Å
218E88.4Confident79.3Confident125 Ų12566 Ų6658%0.58434%0.339SS*.EExtended strand (participates in β ladder)trans-91.4139.3179-74.2-179.7-166.100112.2T196 V197 V198T196-E218 HydrophobicContact CG2-CB 3.99Å; T196-E218 HydrophobicContact CG2-CG 4.14Å; V197-E218 CarbonylContact O-C 3.48Å; V197-E218 WeakPolarHBondContact O-CA 3.23Å; V198-E218 HydrophobicContact CG2-CG 3.91Å
219Y89.3Confident79.3Confident4 Ų459.8 Ų59.82%0.01630%0.298CS..EExtended strand (participates in β ladder)trans-131.7143.4178.7-61.4-94.5000110T196 V197 A199 L211 E212 L213 R214 E217 R233 D234T196-Y219 CarbonylContact C-O 3.56Å; T196-Y219 WeakPolarHBondContact CA-O 3.42Å; V197-Y219 PolarHBondContact N-O 2.67Å; V197-Y219 PolarHBondContact O-N 2.6Å; A199-Y219 HydrophobicContact CB-CD2 4.25Å; A199-Y219 HydrophobicContact CB-CE2 3.79Å; L211-Y219 HydrophobicContact CD2-CD1 3.8Å; L211-Y219 HydrophobicContact CD2-CE1 4.05Å; L211-Y219 HydrophobicContact CG-CE1 4.35Å; E212-Y219 WeakPolarHBondContact O-CE1 3.2Å; E212-Y219 PolarHBondContact O-OH 3.42Å; L213-Y219 VanDerWaalsContact CA-OH 3.28Å; L213-Y219 WeakPolarHBondContact CA-OH 3.37Å; L213-Y219 HydrophobicContact CD2-CD1 4.01Å; L213-Y219 HydrophobicContact CD2-CD2 3.71Å; L213-Y219 HydrophobicContact CD2-CE1 3.83Å; L213-Y219 HydrophobicContact CD2-CE2 3.55Å; L213-Y219 HydrophobicContact CD2-CG 3.96Å; R214-Y219 PolarHBondContact N-OH 2.8Å; E217-Y219 HydrophobicContact CB-CE2 3.79Å; E217-Y219 VanDerWaalsContact O-CD2 3.32Å; E217-Y219 WeakPolarHBondContact O-CD2 3.03Å; E217-Y219 WeakPolarHBondContact O-CE2 3.25Å; Y219-R233 WeakPolarHBondContact CA-O 3.35Å; Y219-D234 HydrophobicContact CD1-CB 3.97Å; Y219-D234 HydrophobicContact CE1-CB 3.76Å
220T90.8Very high79.7Confident47 Ų4755.9 Ų55.929%0.28828%0.278SS..EExtended strand (participates in β ladder)trans-97.6122.2176.5-56.30000109.9L222 A232 R233T220-L222 PolarHBondContact O-N 3.11Å; T220-A232 CarbonylContact O-C 3.59Å; T220-A232 VanDerWaalsContact O-CA 3.26Å; T220-A232 WeakPolarHBondContact O-CA 3.43Å; T220-R233 PolarHBondContact N-O 3.12Å; T220-R233 PolarHBondContact O-N 2.79Å
221I90Very high80Confident13 Ų1358 Ų587%0.06729%0.287CS..EExtended strand (participates in β ladder)trans-77.5122.9177.1-56.3-54.6000109.9I195 V197 R224 W230 A232 I242I195-I221 WeakPolarHBondContact O-CB 3.42Å; I195-I221 PolarHBondContact O-N 3.03Å; V197-I221 HydrophobicContact CB-CD1 4.45Å; V197-I221 HydrophobicContact CB-CG1 4.42Å; V197-I221 HydrophobicContact CG1-CD1 3.98Å; V197-I221 HydrophobicContact CG1-CG1 3.56Å; V197-I221 HydrophobicContact CG2-CD1 3.58Å; V197-I221 HydrophobicContact CG2-CG1 3.98Å; I221-R224 HydrophobicContact CG2-CG 3.67Å; I221-W230 HydrophobicContact CD1-CB 4.13Å; I221-W230 HydrophobicContact CD1-CE3 3.77Å; I221-W230 HydrophobicContact CG1-CE3 4.11Å; I221-W230 HydrophobicContact CG2-CB 4.37Å; I221-A232 HydrophobicContact CD1-CB 3.91Å; I221-I242 HydrophobicContact CD1-CD1 3.92Å
222L86.6Confident80.1Confident58 Ų5858 Ų5830%0.30429%0.287SS..EExtended strand (participates in β ladder)trans-94.8-42.2177.9-57.4179.5000111.4T220 K231 R233 E239T220-L222 PolarHBondContact O-N 3.11Å; L222-K231 PolarHBondContact N-O 3.4Å; L222-R233 HydrophobicContact CD1-CB 4.07Å; L222-R233 HydrophobicContact CD2-CB 4.34Å; L222-R233 HydrophobicContact CG-CB 4.24Å; L222-E239 HydrophobicContact CD1-CB 4.46Å; L222-E239 HydrophobicContact CD1-CG 3.79Å; L222-E239 WeakPolarHBondContact CD1-OE1 3.5Å
223E83.8Confident80.3Confident84 Ų8459.1 Ų59.139%0.39329%0.288SS..EExtended strand (participates in β ladder)trans-144135.8-177-59.2171.5-144.400111.4K231E223-K231 HydrophobicContact CB-CB 3.93Å; E223-K231 HydrophobicContact CG-CB 4.45Å; E223-K231 HydrophobicContact CG-CD 4.24Å; E223-K231 PolarHBondContact N-O 2.78Å; E223-K231 PolarHBondContact O-N 3.05Å; E223-K231 WeakPolarHBondContact OE1-CD 3.33Å; E223-K231 IonicContact OE1-NZ 3.29Å; E223-K231 PolarHBondContact OE1-NZ 2.79Å
224R80.5Confident80.7Confident104 Ų10460.2 Ų60.239%0.39229%0.294SS..  trans-115.138.3175-64.6-176.5173.7-171.9-6.8112I195 I221 D226 W230 E249I195-R224 VanDerWaalsContact CD1-NH2 3.31Å; I221-R224 HydrophobicContact CG2-CG 3.67Å; R224-D226 VanDerWaalsContact C-N 3.31Å; R224-W230 HydrophobicContact CG-CD2 4.33Å; R224-W230 HydrophobicContact CG-CG 4.34Å; R224-E249 IonicContact CZ-OE1 2.76Å; R224-E249 IonicContact NH1-OE1 2.65Å; R224-E249 PolarHBondContact NH1-OE1 2.99Å; R224-E249 VanDerWaalsContact NH1-OE1 3.17Å; R224-E249 IonicContact NH2-OE1 2.96Å; R224-E249 PolarHBondContact NH2-OE1 2.97Å
225S64.9Low80.8Confident87 Ų8760.9 Ų60.961%0.60830%0.3SS*.  trans-69.8-28.8-176.4450000113
226D65.7Low81.4Confident37 Ų3764.3 Ų64.320%0.19831%0.311CS..SBendtrans-110137.6174-174-78.1000110.8R224 N228 W229 W230 Y369R224-D226 VanDerWaalsContact C-N 3.31Å; D226-N228 PolarHBondContact O-N 3.47Å; D226-N228 WeakPolarHBondContact OD1-CA 3.34Å; D226-N228 VanDerWaalsContact OD1-CB 3.31Å; D226-N228 WeakPolarHBondContact OD1-CB 3.32Å; D226-N228 PolarHBondContact OD1-N 3.41Å; D226-W229 WeakPolarHBondContact CB-O 3.09Å; D226-W229 PolarHBondContact OD1-N 3.12Å; D226-W230 PolarHBondContact O-NE1 3.28Å; D226-Y369 HydrophobicContact CB-CD2 4.32Å; D226-Y369 HydrophobicContact CB-CE2 3.56Å; D226-Y369 WeakPolarHBondContact OD2-CE2 3.48Å
227P53.9Low82.1Confident95 Ų9561 Ų6162%0.61730%0.304SS*.SBendtrans-66.4-22.4-179.224-32.5000113.8S244P227-S244 PolarHBondContact O-OG 3.49Å
228N59.6Low82.3Confident41 Ų4164.5 Ų64.522%0.21932%0.318CS..SBendtrans-110.7-24.5-170.5-60.5-49.6000113.7D226 S244 A365 R430D226-N228 PolarHBondContact O-N 3.47Å; D226-N228 WeakPolarHBondContact OD1-CA 3.34Å; D226-N228 VanDerWaalsContact OD1-CB 3.31Å; D226-N228 WeakPolarHBondContact OD1-CB 3.32Å; D226-N228 PolarHBondContact OD1-N 3.41Å; N228-S244 VanDerWaalsContact CA-OG 3.27Å; N228-S244 WeakPolarHBondContact CA-OG 3.5Å; N228-S244 PolarHBondContact O-N 2.82Å; N228-S244 PolarHBondContact O-OG 3.26Å; N228-A365 HydrophobicContact CB-CB 4.33Å; N228-R430 VanDerWaalsContact CG-CZ 3.49Å; N228-R430 PolarHBondContact OD1-NH1 3.17Å
229W75.6Confident82.6Confident8 Ų862.7 Ų62.73%0.0331%0.31CS..EExtended strand (participates in β ladder)trans-130.1117.6-179.8-70.386.5000110.2Y203 D226 Y241 I242 P243 A365 G368 Y369Y203-W229 HydrophobicContact CE1-CZ3 4.37Å; Y203-W229 HydrophobicContact CE2-CH2 4.25Å; Y203-W229 AromaticContact CZ-CH2 3.82Å; Y203-W229 VanDerWaalsContact OH-CH2 3.25Å; Y203-W229 WeakPolarHBondContact OH-CH2 3.37Å; D226-W229 WeakPolarHBondContact CB-O 3.09Å; D226-W229 PolarHBondContact OD1-N 3.12Å; W229-Y241 HydrophobicContact CB-CD1 4.49Å; W229-I242 CarbonylContact C-O 3.49Å; W229-I242 WeakPolarHBondContact CA-O 3.48Å; W229-P243 HydrophobicContact CE3-CG 4.42Å; W229-P243 HydrophobicContact CH2-CG 3.79Å; W229-P243 HydrophobicContact CZ2-CG 4.41Å; W229-P243 HydrophobicContact CZ3-CG 3.82Å; W229-A365 PolarHBondContact NE1-O 3.15Å; W229-G368 VanDerWaalsContact CH2-CA 3.47Å; W229-G368 VanDerWaalsContact CZ2-C 3.46Å; W229-Y369 HydrophobicContact CB-CD2 3.48Å; W229-Y369 VanDerWaalsContact CB-CD2 3.48Å; W229-Y369 HydrophobicContact CB-CE2 4.32Å; W229-Y369 HydrophobicContact CB-CG 4Å; W229-Y369 AromaticContact CD1-CD2 3.92Å; W229-Y369 AromaticContact CG-CD2 3.77Å; W229-Y369 HydrophobicContact CG-CD2 3.77Å; W229-Y369 HydrophobicContact CG-CG 4.17Å
230W85.3Confident82.5Confident40 Ų4062.8 Ų62.815%0.15231%0.312CS..EExtended strand (participates in β ladder)trans-102.8142.6178.2-63.3-14.6000109.8V197 I221 R224 D226 A232 Y241 I242 V247V197-W230 HydrophobicContact CG1-CZ3 4.23Å; I221-W230 HydrophobicContact CD1-CB 4.13Å; I221-W230 HydrophobicContact CD1-CE3 3.77Å; I221-W230 HydrophobicContact CG1-CE3 4.11Å; I221-W230 HydrophobicContact CG2-CB 4.37Å; R224-W230 HydrophobicContact CG-CD2 4.33Å; R224-W230 HydrophobicContact CG-CG 4.34Å; D226-W230 PolarHBondContact O-NE1 3.28Å; W230-A232 PolarHBondContact O-N 3.23Å; W230-Y241 CarbonylContact O-C 3.6Å; W230-Y241 WeakPolarHBondContact O-CA 3.39Å; W230-I242 HydrophobicContact CB-CG1 4.28Å; W230-I242 PolarHBondContact N-O 3.48Å; W230-I242 WeakPolarHBondContact O-CG1 3.35Å; W230-I242 PolarHBondContact O-N 2.8Å; W230-V247 HydrophobicContact CE3-CG2 3.92Å; W230-V247 HydrophobicContact CZ3-CG2 3.88Å
231K88.7Confident82.3Confident47 Ų4762.7 Ų62.720%0.20431%0.307CS..EExtended strand (participates in β ladder)trans-81.3120169.9-166.1178.8175-175.10107.6L222 E223 Y241L222-K231 PolarHBondContact N-O 3.4Å; E223-K231 HydrophobicContact CB-CB 3.93Å; E223-K231 HydrophobicContact CG-CB 4.45Å; E223-K231 HydrophobicContact CG-CD 4.24Å; E223-K231 PolarHBondContact N-O 2.78Å; E223-K231 PolarHBondContact O-N 3.05Å; E223-K231 WeakPolarHBondContact OE1-CD 3.33Å; E223-K231 IonicContact OE1-NZ 3.29Å; E223-K231 PolarHBondContact OE1-NZ 2.79Å; K231-Y241 HydrophobicContact CB-CD1 4.22Å; K231-Y241 HydrophobicContact CB-CE1 3.98Å; K231-Y241 HydrophobicContact CG-CE1 4.41Å
232A91.7Very high82.1Confident0 Ų062 Ų620%030%0.304CS..EExtended strand (participates in β ladder)trans-126.2163.4-177.700000111.3L211 T220 I221 W230 E239 G240 I242L211-A232 HydrophobicContact CD2-CB 4.24Å; T220-A232 CarbonylContact O-C 3.59Å; T220-A232 VanDerWaalsContact O-CA 3.26Å; T220-A232 WeakPolarHBondContact O-CA 3.43Å; I221-A232 HydrophobicContact CD1-CB 3.91Å; W230-A232 PolarHBondContact O-N 3.23Å; A232-E239 WeakPolarHBondContact O-CA 3.28Å; A232-G240 PolarHBondContact N-O 3.08Å; A232-G240 PolarHBondContact O-N 3.11Å; A232-G240 VanDerWaalsContact O-N 3.08Å; A232-I242 HydrophobicContact CB-CD1 3.4Å; A232-I242 HydrophobicContact CB-CG1 3.64Å; A232-I242 HydrophobicContact CB-CG2 4.11Å
233R93.4Very high81.6Confident99 Ų9959.3 Ų59.337%0.37429%0.289SS..EExtended strand (participates in β ladder)trans-123.1131174.2-169.2-175.3-69.9158.8-1.2109.2Y219 T220 L222 K238 E239Y219-R233 WeakPolarHBondContact CA-O 3.35Å; T220-R233 PolarHBondContact N-O 3.12Å; T220-R233 PolarHBondContact O-N 2.79Å; L222-R233 HydrophobicContact CD1-CB 4.07Å; L222-R233 HydrophobicContact CD2-CB 4.34Å; L222-R233 HydrophobicContact CG-CB 4.24Å; R233-K238 WeakPolarHBondContact CA-O 3.45Å; R233-E239 HydrophobicContact CB-CG 4.24Å; R233-E239 HydrophobicContact CG-CG 4.01Å; R233-E239 IonicContact CZ-OE1 2.66Å; R233-E239 VanDerWaalsContact CZ-OE1 3.23Å; R233-E239 IonicContact NE-OE1 3.21Å; R233-E239 PolarHBondContact NE-OE1 2.81Å; R233-E239 IonicContact NH2-OE1 3.9Å; R233-E239 PolarHBondContact NH2-OE1 3.47Å
234D92Very high81.1Confident25 Ų2556.1 Ų56.113%0.13428%0.276CS..  trans-78.2174.8173.473.210.7000112L211 Y219 Y236 G237 K238L211-D234 HydrophobicContact CD1-CB 4.26Å; L211-D234 HydrophobicContact CD2-CB 4.2Å; Y219-D234 HydrophobicContact CD1-CB 3.97Å; Y219-D234 HydrophobicContact CE1-CB 3.76Å; D234-Y236 PolarHBondContact O-N 2.78Å; D234-Y236 VanDerWaalsContact OD1-C 3.28Å; D234-Y236 VanDerWaalsContact OD1-CA 3.29Å; D234-Y236 WeakPolarHBondContact OD1-CA 3.49Å; D234-Y236 WeakPolarHBondContact OD1-CB 3.49Å; D234-Y236 PolarHBondContact OD1-N 3.39Å; D234-G237 PolarHBondContact O-N 2.91Å; D234-G237 VanDerWaalsContact O-N 3.12Å; D234-G237 PolarHBondContact OD1-N 3.03Å; D234-K238 PolarHBondContact N-O 2.88Å; D234-K238 PolarHBondContact OD1-N 3.08Å; D234-K238 WeakPolarHBondContact OD2-CB 3.39Å
235K86.5Confident80.2Confident121 Ų12153.6 Ų53.653%0.52627%0.27SS..THydrogen-bonded Turntrans-62.6-16.817665.6-172.9166.6-169.10114.7E217E217-K235 IonicContact OE1-NZ 3.71Å; E217-K235 PolarHBondContact OE1-NZ 3.25Å; E217-K235 VanDerWaalsContact OE2-CE 3.28Å; E217-K235 WeakPolarHBondContact OE2-CE 3.31Å; E217-K235 IonicContact OE2-NZ 2.64Å; E217-K235 PolarHBondContact OE2-NZ 2.93Å
236Y87.9Confident80.4Confident164 Ų16450.6 Ų50.664%0.64325%0.246SC*.THydrogen-bonded Turntrans-94.8-1.5179.1-55.6-70.6000112.4D234D234-Y236 PolarHBondContact O-N 2.78Å; D234-Y236 VanDerWaalsContact OD1-C 3.28Å; D234-Y236 VanDerWaalsContact OD1-CA 3.29Å; D234-Y236 WeakPolarHBondContact OD1-CA 3.49Å; D234-Y236 WeakPolarHBondContact OD1-CB 3.49Å; D234-Y236 PolarHBondContact OD1-N 3.39Å
237G84.4Confident80.5Confident44 Ų4449.3 Ų49.345%0.45424%0.239SC..SBendtrans856.7-179.300000114.4D234D234-G237 PolarHBondContact O-N 2.91Å; D234-G237 VanDerWaalsContact O-N 3.12Å; D234-G237 PolarHBondContact OD1-N 3.03Å
238K89.8Confident81.1Confident111 Ų11146.7 Ų46.748%0.48322%0.221SC..  trans-74.9131.6173.9-170-176.3174.1-171.60109.2L211 R233 D234L211-K238 HydrophobicContact CD1-CB 4Å; L211-K238 HydrophobicContact CD1-CD 3.81Å; L211-K238 HydrophobicContact CD1-CG 3.83Å; R233-K238 WeakPolarHBondContact CA-O 3.45Å; D234-K238 PolarHBondContact N-O 2.88Å; D234-K238 PolarHBondContact OD1-N 3.08Å; D234-K238 WeakPolarHBondContact OD2-CB 3.39Å
239E93.4Very high81.7Confident87 Ų8749.7 Ų49.741%0.40723%0.234SC..EExtended strand (participates in β ladder)trans-105.5147.3177.5-60.3-174.417800110.8L222 A232 R233L222-E239 HydrophobicContact CD1-CB 4.46Å; L222-E239 HydrophobicContact CD1-CG 3.79Å; L222-E239 WeakPolarHBondContact CD1-OE1 3.5Å; A232-E239 WeakPolarHBondContact O-CA 3.28Å; R233-E239 HydrophobicContact CB-CG 4.24Å; R233-E239 HydrophobicContact CG-CG 4.01Å; R233-E239 IonicContact CZ-OE1 2.66Å; R233-E239 VanDerWaalsContact CZ-OE1 3.23Å; R233-E239 IonicContact NE-OE1 3.21Å; R233-E239 PolarHBondContact NE-OE1 2.81Å; R233-E239 IonicContact NH2-OE1 3.9Å; R233-E239 PolarHBondContact NH2-OE1 3.47Å
240G88.9Confident81Confident6 Ų651 Ų516%0.06225%0.247CC..EExtended strand (participates in β ladder)trans-179.6-179.617200000111.2Q209 A232Q209-G240 CarbonylContact O-C 3.59Å; Q209-G240 VanDerWaalsContact O-CA 3.23Å; Q209-G240 WeakPolarHBondContact O-CA 3.5Å; A232-G240 PolarHBondContact N-O 3.08Å; A232-G240 PolarHBondContact O-N 3.11Å; A232-G240 VanDerWaalsContact O-N 3.08Å
241Y85.3Confident79.7Confident45 Ų4552.2 Ų52.218%0.17625%0.254CS..EExtended strand (participates in β ladder)trans-87.6137.4178.3-67.6-83000111.1Q209 D210 L211 W229 W230 K231 Y369Q209-Y241 HydrophobicContact CB-CD2 4.27Å; Q209-Y241 PolarHBondContact O-N 3.48Å; D210-Y241 VanDerWaalsContact CA-O 3.31Å; D210-Y241 WeakPolarHBondContact CA-O 3.46Å; L211-Y241 PolarHBondContact N-O 3.49Å; W229-Y241 HydrophobicContact CB-CD1 4.49Å; W230-Y241 CarbonylContact O-C 3.6Å; W230-Y241 WeakPolarHBondContact O-CA 3.39Å; K231-Y241 HydrophobicContact CB-CD1 4.22Å; K231-Y241 HydrophobicContact CB-CE1 3.98Å; K231-Y241 HydrophobicContact CG-CE1 4.41Å; Y241-Y369 HydrophobicContact CD1-CD1 4.27Å; Y241-Y369 HydrophobicContact CD1-CG 4.33Å; Y241-Y369 HydrophobicContact CD2-CD1 4.39Å; Y241-Y369 HydrophobicContact CE1-CD1 4.14Å; Y241-Y369 HydrophobicContact CE1-CE1 4.2Å; Y241-Y369 HydrophobicContact CE2-CD1 4.26Å; Y241-Y369 HydrophobicContact CG-CD1 4.39Å; Y241-Y369 HydrophobicContact CG-CG 4.45Å
242I86.1Confident78Confident0 Ų059.5 Ų59.50%029%0.286CS..EExtended strand (participates in β ladder)trans-124.4146177.260.6165.3000109.7V197 L211 L213 I221 W229 W230 A232 S244 V247V197-I242 HydrophobicContact CG2-CD1 4.37Å; L211-I242 HydrophobicContact CB-CG2 3.68Å; L211-I242 HydrophobicContact CD2-CG2 4.09Å; L211-I242 HydrophobicContact CG-CG2 4.23Å; L213-I242 HydrophobicContact CD1-CB 4.15Å; L213-I242 HydrophobicContact CD1-CG2 4.5Å; L213-I242 HydrophobicContact CD2-CB 3.96Å; L213-I242 HydrophobicContact CD2-CD1 4.06Å; L213-I242 HydrophobicContact CD2-CG2 3.56Å; L213-I242 HydrophobicContact CG-CB 4.21Å; L213-I242 HydrophobicContact CG-CG2 4.01Å; I221-I242 HydrophobicContact CD1-CD1 3.92Å; W229-I242 CarbonylContact C-O 3.49Å; W229-I242 WeakPolarHBondContact CA-O 3.48Å; W230-I242 HydrophobicContact CB-CG1 4.28Å; W230-I242 PolarHBondContact N-O 3.48Å; W230-I242 WeakPolarHBondContact O-CG1 3.35Å; W230-I242 PolarHBondContact O-N 2.8Å; A232-I242 HydrophobicContact CB-CD1 3.4Å; A232-I242 HydrophobicContact CB-CG1 3.64Å; A232-I242 HydrophobicContact CB-CG2 4.11Å; I242-S244 PolarHBondContact O-N 3.33Å; I242-V247 HydrophobicContact CD1-CB 4.43Å; I242-V247 HydrophobicContact CD1-CG1 3.68Å; I242-V247 HydrophobicContact CD1-CG2 3.98Å
243P75.6Confident76.8Confident0 Ų061.8 Ų61.80%031%0.31CS..EExtended strand (participates in β ladder)trans-65.2125.4172.5-14.226.8000110.2Y203 W229 N245 Y246Y203-P243 HydrophobicContact CD1-CG 4.35Å; Y203-P243 HydrophobicContact CD2-CG 3.7Å; Y203-P243 HydrophobicContact CE1-CG 4.35Å; Y203-P243 HydrophobicContact CE2-CG 3.71Å; Y203-P243 HydrophobicContact CG-CG 4.05Å; W229-P243 HydrophobicContact CE3-CG 4.42Å; W229-P243 HydrophobicContact CH2-CG 3.79Å; W229-P243 HydrophobicContact CZ2-CG 4.41Å; W229-P243 HydrophobicContact CZ3-CG 3.82Å; P243-N245 WeakPolarHBondContact CB-OD1 3.41Å; P243-N245 PolarHBondContact O-N 3.2Å; P243-Y246 HydrophobicContact CB-CD2 3.68Å; P243-Y246 HydrophobicContact CB-CE2 4.44Å; P243-Y246 HydrophobicContact CB-CG 3.99Å; P243-Y246 HydrophobicContact CG-CD2 4.1Å; P243-Y246 HydrophobicContact CG-CG 4.11Å; P243-Y246 WeakPolarHBondContact O-CB 3.32Å; P243-Y246 PolarHBondContact O-N 3.29Å; P243-Y246 VanDerWaalsContact O-N 3.07Å
244S74Confident75.6Confident18 Ų1858.4 Ų58.413%0.12630%0.299CS..G310 helixtrans-64.7-26.4-178.461.30000113P227 N228 I242 Y246 V247P227-S244 PolarHBondContact O-OG 3.49Å; N228-S244 VanDerWaalsContact CA-OG 3.27Å; N228-S244 WeakPolarHBondContact CA-OG 3.5Å; N228-S244 PolarHBondContact O-N 2.82Å; N228-S244 PolarHBondContact O-OG 3.26Å; I242-S244 PolarHBondContact O-N 3.33Å; S244-Y246 VanDerWaalsContact C-N 3.27Å; S244-Y246 PolarHBondContact O-N 3.07Å; S244-V247 WeakPolarHBondContact O-CG2 3.11Å; S244-V247 VanDerWaalsContact O-O 3.11Å
245N62.1Low74.5Confident50 Ų5060 Ų6027%0.26731%0.306SS..G310 helixtrans-80.6-3176.568.6-50000114.1P243P243-N245 WeakPolarHBondContact CB-OD1 3.41Å; P243-N245 PolarHBondContact O-N 3.2Å
246Y68.2Low73.5Confident25 Ų2561.9 Ų61.910%0.09831%0.309CS..G310 helixtrans-98.1-3.6176.8-85.4-123.9000112.6A199 E200 Y201 Y203 L213 P243 S244 T364A199-Y246 WeakPolarHBondContact CA-O 3.13Å; E200-Y246 PolarHBondContact N-O 3.37Å; Y201-Y246 HydrophobicContact CD2-CD1 4.42Å; Y201-Y246 HydrophobicContact CD2-CG 4.42Å; Y203-Y246 HydrophobicContact CD2-CD1 4.34Å; Y203-Y246 HydrophobicContact CD2-CE1 4.2Å; Y203-Y246 HydrophobicContact CG-CD1 4.46Å; L213-Y246 VanDerWaalsContact CD1-CB 3.43Å; L213-Y246 HydrophobicContact CD1-CD1 4.39Å; L213-Y246 HydrophobicContact CD1-CG 4.33Å; P243-Y246 HydrophobicContact CB-CD2 3.68Å; P243-Y246 HydrophobicContact CB-CE2 4.44Å; P243-Y246 HydrophobicContact CB-CG 3.99Å; P243-Y246 HydrophobicContact CG-CD2 4.1Å; P243-Y246 HydrophobicContact CG-CG 4.11Å; P243-Y246 WeakPolarHBondContact O-CB 3.32Å; P243-Y246 PolarHBondContact O-N 3.29Å; P243-Y246 VanDerWaalsContact O-N 3.07Å; S244-Y246 VanDerWaalsContact C-N 3.27Å; S244-Y246 PolarHBondContact O-N 3.07Å; Y246-T364 HydrophobicContact CE2-CG2 3.9Å; Y246-T364 WeakPolarHBondContact OH-CG2 3.06Å
247V68.8Low72.7Confident9 Ų956.2 Ų56.26%0.05529%0.288CS..EExtended strand (participates in β ladder)trans-131.9141-175.2-620000110.2V197 V198 A199 L213 W230 I242 S244V197-V247 HydrophobicContact CB-CB 3.92Å; V197-V247 HydrophobicContact CB-CG2 4.16Å; V197-V247 HydrophobicContact CG1-CG2 4.42Å; V197-V247 HydrophobicContact CG2-CB 3.73Å; V197-V247 HydrophobicContact CG2-CG1 4.06Å; V197-V247 HydrophobicContact CG2-CG2 3.92Å; V198-V247 CarbonylContact O-C 3.55Å; V198-V247 VanDerWaalsContact O-CA 3.28Å; V198-V247 WeakPolarHBondContact O-CA 3.22Å; A199-V247 HydrophobicContact CB-CG1 4.35Å; L213-V247 HydrophobicContact CD1-CG1 3.65Å; L213-V247 HydrophobicContact CD2-CG1 3.91Å; L213-V247 HydrophobicContact CG-CG1 4.45Å; W230-V247 HydrophobicContact CE3-CG2 3.92Å; W230-V247 HydrophobicContact CZ3-CG2 3.88Å; I242-V247 HydrophobicContact CD1-CB 4.43Å; I242-V247 HydrophobicContact CD1-CG1 3.68Å; I242-V247 HydrophobicContact CD1-CG2 3.98Å; S244-V247 WeakPolarHBondContact O-CG2 3.11Å; S244-V247 VanDerWaalsContact O-O 3.11Å
248V65.6Low72.1Confident40 Ų4057 Ų5724%0.24228%0.282CS..EExtended strand (participates in β ladder)trans-111.3147.1172.5-71.30000109.1V197 V198 E200 A250V197-V248 CarbonylContact C-O 3.56Å; V197-V248 WeakPolarHBondContact CA-O 3.39Å; V197-V248 VanDerWaalsContact CB-O 3.22Å; V197-V248 WeakPolarHBondContact CB-O 3.37Å; V198-V248 HydrophobicContact CB-CG2 4.41Å; V198-V248 PolarHBondContact N-O 2.97Å; V198-V248 PolarHBondContact O-N 2.85Å; E200-V248 VanDerWaalsContact CD-CG1 3.42Å; E200-V248 HydrophobicContact CG-CB 4.33Å; E200-V248 HydrophobicContact CG-CG1 3.71Å; E200-V248 HydrophobicContact CG-CG2 3.78Å; E200-V248 WeakPolarHBondContact OE1-CG1 3.5Å; V248-A250 PolarHBondContact O-N 2.84Å
249E71.8Confident71.9Confident104 Ų10452.5 Ų52.549%0.48626%0.262SS..EExtended strand (participates in β ladder)trans-55.8135.8169.8-67.2-167.3167.700108.9I195 V197 R224 E251I195-E249 HydrophobicContact CG2-CG 4.13Å; V197-E249 HydrophobicContact CG1-CG 4.48Å; R224-E249 IonicContact CZ-OE1 2.76Å; R224-E249 IonicContact NH1-OE1 2.65Å; R224-E249 PolarHBondContact NH1-OE1 2.99Å; R224-E249 VanDerWaalsContact NH1-OE1 3.17Å; R224-E249 IonicContact NH2-OE1 2.96Å; R224-E249 PolarHBondContact NH2-OE1 2.97Å; E249-E251 PolarHBondContact O-N 3.47Å
250A62.3Low71.4Confident36 Ų3649.2 Ų49.230%0.29825%0.246SC..  trans-56.3101.6-174.900000109.9T196 V198 V248 K252T196-A250 HydrophobicContact CG2-CB 4.34Å; T196-A250 WeakPolarHBondContact O-CB 3.4Å; T196-A250 PolarHBondContact O-N 3.12Å; V198-A250 HydrophobicContact CG2-CB 4.02Å; V248-A250 PolarHBondContact O-N 2.84Å; A250-K252 PolarHBondContact O-N 3.3Å
251E57.2Low71Confident65 Ų6549 Ų4930%0.30424%0.243SC..  trans-66.3129.4-171.1-69.1179.8150.300110.1E249 E255 R256 R358E249-E251 PolarHBondContact O-N 3.47Å; E251-E255 HydrophobicContact CB-CB 4.01Å; E251-E255 HydrophobicContact CG-CB 4.24Å; E251-E255 WeakPolarHBondContact OE2-CB 3.36Å; E251-R256 WeakPolarHBondContact OE2-CA 3.19Å; E251-R256 PolarHBondContact OE2-N 3.13Å; E251-R256 VanDerWaalsContact OE2-N 3.08Å; E251-R358 IonicContact OE1-NH2 3.57Å; E251-R358 IonicContact OE2-NH2 2.73Å; E251-R358 PolarHBondContact OE2-NH2 3.39Å
252K53.5Low70.5Confident201 Ų20151.2 Ų51.287%0.87425%0.254SS*.  trans-86.8117.2174.8-67.9-180-179.1175.40109.5A250A250-K252 PolarHBondContact O-N 3.3Å
253G66.4Low69.8Low48 Ų4858.2 Ų58.250%0.49529%0.291SS..SBendtrans112.8-135.3168.400000114.7R256G253-R256 WeakPolarHBondContact O-CG 3.46Å
254L68.1Low70.1Confident28 Ų2859.1 Ų59.115%0.14730%0.296CS..SBendtrans-84.5-16.8-177.1-62.4175.7000113.7R256 F257 W259 Y260 Y293 I333 P334L254-R256 PolarHBondContact O-N 3.43Å; L254-F257 HydrophobicContact CD2-CD2 4.38Å; L254-F257 HydrophobicContact CD2-CE2 4.37Å; L254-F257 PolarHBondContact O-N 3.45Å; L254-F257 VanDerWaalsContact O-N 3.12Å; L254-W259 HydrophobicContact CD2-CH2 4.11Å; L254-Y260 HydrophobicContact CB-CD1 3.82Å; L254-Y260 HydrophobicContact CB-CD2 4.05Å; L254-Y260 HydrophobicContact CB-CE1 4.01Å; L254-Y260 HydrophobicContact CB-CE2 4.24Å; L254-Y260 HydrophobicContact CB-CG 3.83Å; L254-Y260 HydrophobicContact CD1-CD2 4.37Å; L254-Y260 HydrophobicContact CD1-CE2 4.12Å; L254-Y260 VanDerWaalsContact O-CB 3.23Å; L254-Y260 WeakPolarHBondContact O-CB 3.35Å; L254-Y293 HydrophobicContact CD1-CD1 4.26Å; L254-Y293 HydrophobicContact CD1-CE1 3.79Å; L254-Y293 HydrophobicContact CD1-CE2 4.18Å; L254-I333 HydrophobicContact CD1-CB 4.46Å; L254-I333 HydrophobicContact CD1-CD1 3.61Å; L254-I333 HydrophobicContact CD1-CG2 4.5Å; L254-I333 HydrophobicContact CD2-CB 4.04Å; L254-I333 HydrophobicContact CD2-CG2 4.33Å; L254-P334 HydrophobicContact CD2-CG 4.16Å
255E68.4Low70.6Confident59 Ų5962 Ų6228%0.27631%0.31SS..THydrogen-bonded Turntrans-57.7-34.9179.7-67.8171.1-164.200111.7E251 F257 Y260 K262 R358E251-E255 HydrophobicContact CB-CB 4.01Å; E251-E255 HydrophobicContact CG-CB 4.24Å; E251-E255 WeakPolarHBondContact OE2-CB 3.36Å; E255-F257 PolarHBondContact O-N 2.89Å; E255-Y260 HydrophobicContact CG-CD1 4.1Å; E255-Y260 HydrophobicContact CG-CE1 3.97Å; E255-K262 WeakPolarHBondContact OE1-CD 3.38Å; E255-K262 VanDerWaalsContact OE1-CE 3.3Å; E255-K262 WeakPolarHBondContact OE1-CE 3.3Å; E255-K262 IonicContact OE1-NZ 3.33Å; E255-K262 PolarHBondContact OE1-NZ 2.85Å; E255-R358 PolarHBondContact O-NH2 3.11Å
256R65.5Low71.6Confident159 Ų15966.4 Ų66.460%0.632%0.323SS*.THydrogen-bonded Turntrans-57.9-17.3177.274.4-177.8174172.2-3.3115.2E251 G253 L254E251-R256 WeakPolarHBondContact OE2-CA 3.19Å; E251-R256 PolarHBondContact OE2-N 3.13Å; E251-R256 VanDerWaalsContact OE2-N 3.08Å; G253-R256 WeakPolarHBondContact O-CG 3.46Å; L254-R256 PolarHBondContact O-N 3.43Å
257F71.9Confident72.3Confident45 Ų4569.1 Ų69.120%0.19735%0.345CS..SBendtrans-96.7124.1-176.5-62.7-77.5000110.8L254 E255 W259 Y260 P334L254-F257 HydrophobicContact CD2-CD2 4.38Å; L254-F257 HydrophobicContact CD2-CE2 4.37Å; L254-F257 PolarHBondContact O-N 3.45Å; L254-F257 VanDerWaalsContact O-N 3.12Å; E255-F257 PolarHBondContact O-N 2.89Å; F257-W259 HydrophobicContact CB-CD2 3.74Å; F257-W259 HydrophobicContact CB-CE3 4.23Å; F257-W259 HydrophobicContact CB-CG 4.21Å; F257-W259 HydrophobicContact CB-CH2 4.13Å; F257-W259 HydrophobicContact CB-CZ2 3.57Å; F257-W259 HydrophobicContact CB-CZ3 4.43Å; F257-W259 AromaticContact CD1-CE2 4Å; F257-W259 AromaticContact CD1-CZ2 3.86Å; F257-W259 HydrophobicContact CD1-CZ2 3.86Å; F257-W259 AromaticContact CD1-NE1 3.81Å; F257-W259 AromaticContact CD2-CH2 3.98Å; F257-W259 HydrophobicContact CD2-CH2 3.98Å; F257-W259 AromaticContact CD2-CZ2 3.69Å; F257-W259 HydrophobicContact CD2-CZ2 3.69Å; F257-W259 HydrophobicContact CE1-CZ2 4.45Å; F257-W259 HydrophobicContact CE2-CZ2 4.32Å; F257-W259 AromaticContact CG-CE2 3.67Å; F257-W259 HydrophobicContact CG-CH2 4.1Å; F257-W259 AromaticContact CG-CZ2 3.43Å; F257-W259 HydrophobicContact CG-CZ2 3.43Å; F257-W259 VanDerWaalsContact CG-CZ2 3.43Å; F257-W259 AromaticContact CG-NE1 3.89Å; F257-W259 PolarHBondContact O-N 3.3Å; F257-Y260 WeakPolarHBondContact O-CB 3.4Å; F257-Y260 PolarHBondContact O-N 3.41Å; F257-P334 HydrophobicContact CD2-CG 4.09Å; F257-P334 HydrophobicContact CE1-CB 4.13Å; F257-P334 HydrophobicContact CE1-CG 4.15Å; F257-P334 HydrophobicContact CE2-CB 4.13Å; F257-P334 HydrophobicContact CE2-CG 3.27Å; F257-P334 HydrophobicContact CZ-CB 3.68Å; F257-P334 HydrophobicContact CZ-CG 3.29Å
258D71.9Confident73Confident61 Ų6172.2 Ų72.233%0.32636%0.359SS..THydrogen-bonded Turntrans-54-24.2-178.1-68.5-29.3000114.8Y260 I354 S356 R358D258-Y260 VanDerWaalsContact C-N 3.33Å; D258-I354 HydrophobicContact CB-CG2 4.19Å; D258-S356 WeakPolarHBondContact O-CB 3.39Å; D258-S356 PolarHBondContact O-OG 2.84Å; D258-R358 IonicContact OD1-CZ 2.69Å; D258-R358 IonicContact OD1-NH1 2.96Å; D258-R358 PolarHBondContact OD1-NH1 2.81Å
259W84.7Confident73.8Confident17 Ų1770.3 Ų70.36%0.06435%0.348CS..THydrogen-bonded Turntrans-81.1-7.5177.750-106.4000114L254 F257 F282 L283 I284 I333 P334 I337 I354L254-W259 HydrophobicContact CD2-CH2 4.11Å; F257-W259 HydrophobicContact CB-CD2 3.74Å; F257-W259 HydrophobicContact CB-CE3 4.23Å; F257-W259 HydrophobicContact CB-CG 4.21Å; F257-W259 HydrophobicContact CB-CH2 4.13Å; F257-W259 HydrophobicContact CB-CZ2 3.57Å; F257-W259 HydrophobicContact CB-CZ3 4.43Å; F257-W259 AromaticContact CD1-CE2 4Å; F257-W259 AromaticContact CD1-CZ2 3.86Å; F257-W259 HydrophobicContact CD1-CZ2 3.86Å; F257-W259 AromaticContact CD1-NE1 3.81Å; F257-W259 AromaticContact CD2-CH2 3.98Å; F257-W259 HydrophobicContact CD2-CH2 3.98Å; F257-W259 AromaticContact CD2-CZ2 3.69Å; F257-W259 HydrophobicContact CD2-CZ2 3.69Å; F257-W259 HydrophobicContact CE1-CZ2 4.45Å; F257-W259 HydrophobicContact CE2-CZ2 4.32Å; F257-W259 AromaticContact CG-CE2 3.67Å; F257-W259 HydrophobicContact CG-CH2 4.1Å; F257-W259 AromaticContact CG-CZ2 3.43Å; F257-W259 HydrophobicContact CG-CZ2 3.43Å; F257-W259 VanDerWaalsContact CG-CZ2 3.43Å; F257-W259 AromaticContact CG-NE1 3.89Å; F257-W259 PolarHBondContact O-N 3.3Å; W259-F282 HydrophobicContact CB-CE2 3.92Å; W259-F282 HydrophobicContact CB-CZ 4.32Å; W259-F282 HydrophobicContact CG-CE2 4.31Å; W259-L283 CarbonylContact O-C 3.53Å; W259-I284 HydrophobicContact CB-CD1 3.94Å; W259-I284 HydrophobicContact CD2-CD1 3.69Å; W259-I284 HydrophobicContact CE3-CB 3.72Å; W259-I284 HydrophobicContact CE3-CD1 3.2Å; W259-I284 HydrophobicContact CE3-CG1 3.66Å; W259-I284 HydrophobicContact CG-CD1 4.04Å; W259-I284 HydrophobicContact CZ3-CB 3.94Å; W259-I284 HydrophobicContact CZ3-CD1 3.9Å; W259-I284 HydrophobicContact CZ3-CG1 3.92Å; W259-I284 HydrophobicContact CZ3-CG2 4.25Å; W259-I284 PolarHBondContact O-N 3.48Å; W259-I333 HydrophobicContact CH2-CG2 3.81Å; W259-I333 HydrophobicContact CZ3-CG2 4.08Å; W259-P334 HydrophobicContact CH2-CG 4.27Å; W259-P334 HydrophobicContact CZ2-CB 4.25Å; W259-P334 HydrophobicContact CZ2-CG 4.13Å; W259-I337 HydrophobicContact CH2-CG1 4.15Å; W259-I337 HydrophobicContact CZ2-CB 4.43Å; W259-I337 HydrophobicContact CZ2-CG1 4.22Å; W259-I337 HydrophobicContact CZ3-CG1 4.33Å; W259-I354 HydrophobicContact CB-CG1 4.34Å; W259-I354 HydrophobicContact CB-CG2 3.88Å
260Y83.7Confident74.6Confident17 Ų1767.4 Ų67.47%0.06733%0.334CS..EExtended strand (participates in β ladder)trans-99.2113.6-177.7-174.2-109.2000111.9L254 E255 F257 D258 K262 I284 D286 Y293L254-Y260 HydrophobicContact CB-CD1 3.82Å; L254-Y260 HydrophobicContact CB-CD2 4.05Å; L254-Y260 HydrophobicContact CB-CE1 4.01Å; L254-Y260 HydrophobicContact CB-CE2 4.24Å; L254-Y260 HydrophobicContact CB-CG 3.83Å; L254-Y260 HydrophobicContact CD1-CD2 4.37Å; L254-Y260 HydrophobicContact CD1-CE2 4.12Å; L254-Y260 VanDerWaalsContact O-CB 3.23Å; L254-Y260 WeakPolarHBondContact O-CB 3.35Å; E255-Y260 HydrophobicContact CG-CD1 4.1Å; E255-Y260 HydrophobicContact CG-CE1 3.97Å; F257-Y260 WeakPolarHBondContact O-CB 3.4Å; F257-Y260 PolarHBondContact O-N 3.41Å; D258-Y260 VanDerWaalsContact C-N 3.33Å; Y260-K262 HydrophobicContact CD1-CB 4.41Å; Y260-K262 HydrophobicContact CE1-CB 3.67Å; Y260-K262 HydrophobicContact CE1-CG 4.08Å; Y260-I284 CarbonylContact C-O 3.6Å; Y260-I284 WeakPolarHBondContact CA-O 3.42Å; Y260-I284 HydrophobicContact CD2-CB 4.12Å; Y260-I284 HydrophobicContact CD2-CG2 3.78Å; Y260-I284 HydrophobicContact CE2-CG2 4.17Å; Y260-D286 PolarHBondContact OH-OD1 2.85Å; Y260-Y293 AromaticContact CE2-CD1 3.77Å; Y260-Y293 HydrophobicContact CE2-CD1 3.77Å; Y260-Y293 AromaticContact CE2-CE1 3.89Å; Y260-Y293 HydrophobicContact CE2-CE1 3.89Å; Y260-Y293 AromaticContact CZ-CE1 3.99Å; Y260-Y293 WeakPolarHBondContact OH-CE1 3.4Å
261C81.1Confident75.6Confident2 Ų270.8 Ų70.81%0.01434%0.344CS..EExtended strand (participates in β ladder)trans-111.886.6178.1-57.80000109.3N263 M264 I284 R285C261-N263 PolarHBondContact O-N 3.07Å; C261-M264 HydrophobicContact CB-CB 3.64Å; C261-M264 HydrophobicContact CB-CE 3.82Å; C261-M264 HydrophobicContact CB-CG 4.19Å; C261-M264 VanDerWaalsContact O-CB 3.23Å; C261-M264 WeakPolarHBondContact O-CB 3.24Å; C261-M264 PolarHBondContact O-N 3.32Å; C261-I284 PolarHBondContact N-O 3.03Å; C261-R285 WeakPolarHBondContact O-CA 3.38Å; C261-R285 WeakPolarHBondContact O-CB 3.36Å
262K74.6Confident76.8Confident91 Ų9169.6 Ų69.640%0.39634%0.339SS..THydrogen-bonded Turntrans-50.5-61-172.1-170.6-178.5-167.4170.20113.8E255 Y260 M264 D286E255-K262 WeakPolarHBondContact OE1-CD 3.38Å; E255-K262 VanDerWaalsContact OE1-CE 3.3Å; E255-K262 WeakPolarHBondContact OE1-CE 3.3Å; E255-K262 IonicContact OE1-NZ 3.33Å; E255-K262 PolarHBondContact OE1-NZ 2.85Å; Y260-K262 HydrophobicContact CD1-CB 4.41Å; Y260-K262 HydrophobicContact CE1-CB 3.67Å; Y260-K262 HydrophobicContact CE1-CG 4.08Å; K262-M264 PolarHBondContact O-N 3.49Å; K262-M264 VanDerWaalsContact O-N 3.15Å; K262-D286 WeakPolarHBondContact CG-OD2 3.41Å; K262-D286 WeakPolarHBondContact O-CB 3.41Å
263N71.1Confident78.2Confident147 Ų14760.1 Ų60.179%0.78630%0.298SS*.THydrogen-bonded Turntrans-87.929.9-174.5-63-25.2000113.3C261C261-N263 PolarHBondContact O-N 3.07Å
264M81.3Confident78.9Confident20 Ų2062.6 Ų62.610%0.09930%0.295CS..  trans-95124.3-177.1-171.673.46800110.5C261 K262 Q268 A269 L272 L283 R285 N357C261-M264 HydrophobicContact CB-CB 3.64Å; C261-M264 HydrophobicContact CB-CE 3.82Å; C261-M264 HydrophobicContact CB-CG 4.19Å; C261-M264 VanDerWaalsContact O-CB 3.23Å; C261-M264 WeakPolarHBondContact O-CB 3.24Å; C261-M264 PolarHBondContact O-N 3.32Å; K262-M264 PolarHBondContact O-N 3.49Å; K262-M264 VanDerWaalsContact O-N 3.15Å; M264-Q268 HydrophobicContact CG-CB 4.3Å; M264-Q268 HydrophobicContact SD-CB 3.39Å; M264-Q268 WeakPolarHBondContact SD-CB 3.44Å; M264-A269 HydrophobicContact CG-CB 3.91Å; M264-L272 HydrophobicContact CE-CD2 3.81Å; M264-L283 HydrophobicContact CG-CD1 4.39Å; M264-R285 HydrophobicContact CB-CB 3.89Å; M264-R285 VanDerWaalsContact O-CD 3.26Å; M264-R285 WeakPolarHBondContact O-CD 3.49Å; M264-N357 HydrophobicContact CE-CB 3.69Å
265N83.8Confident79.4Confident77 Ų7765.3 Ų65.341%0.41232%0.317SS..  trans-85.7172.5173.977.242.7000111.9S267 Q268 A269N265-S267 PolarHBondContact O-N 2.9Å; N265-S267 WeakPolarHBondContact OD1-CB 2.96Å; N265-S267 PolarHBondContact OD1-N 2.79Å; N265-Q268 PolarHBondContact ND2-OE1 3.08Å; N265-Q268 VanDerWaalsContact ND2-OE1 3.13Å; N265-Q268 WeakPolarHBondContact OD1-CG 3.27Å; N265-Q268 PolarHBondContact OD1-N 2.95Å; N265-A269 WeakPolarHBondContact O-CB 3.43Å; N265-A269 PolarHBondContact O-N 2.77Å
266R84.4Confident79.7Confident143 Ų14366.5 Ų66.554%0.5432%0.322SS..Hα-helixtrans-60.2-45.8-178.1-177.6179.7171.7173.6-2.7112.4A269 E270 H311R266-A269 PolarHBondContact O-N 3.41Å; R266-E270 IonicContact CZ-OE1 3.45Å; R266-E270 IonicContact NE-OE1 3.17Å; R266-E270 PolarHBondContact NE-OE1 3.2Å; R266-E270 IonicContact NH2-OE1 2.77Å; R266-E270 PolarHBondContact NH2-OE1 3.36Å; R266-E270 WeakPolarHBondContact O-CG 3.36Å; R266-E270 PolarHBondContact O-N 3.15Å; R266-H311 PolarHBondContact NE-CD2 3.42Å; R266-H311 VanDerWaalsContact NE-CD2 3.33Å; R266-H311 PolarHBondContact NE-NE2 3.17Å
267S82.6Confident80.2Confident83 Ų8362.4 Ų62.458%0.5831%0.312SS*.Hα-helixtrans-65.1-47.4-176.8-1660000111.2N265 A269 E270 Q271N265-S267 PolarHBondContact O-N 2.9Å; N265-S267 WeakPolarHBondContact OD1-CB 2.96Å; N265-S267 PolarHBondContact OD1-N 2.79Å; S267-A269 VanDerWaalsContact C-N 3.31Å; S267-A269 PolarHBondContact O-N 3.33Å; S267-E270 PolarHBondContact O-N 3.2Å; S267-E270 VanDerWaalsContact O-N 3.1Å; S267-Q271 PolarHBondContact O-N 3.13Å
268Q82.8Confident80.4Confident73 Ų7364.6 Ų64.634%0.34132%0.322SS..Hα-helixtrans-59.9-41176.8-67.6168.4-3500111.7M264 N265 Q271 L272M264-Q268 HydrophobicContact CG-CB 4.3Å; M264-Q268 HydrophobicContact SD-CB 3.39Å; M264-Q268 WeakPolarHBondContact SD-CB 3.44Å; N265-Q268 PolarHBondContact ND2-OE1 3.08Å; N265-Q268 VanDerWaalsContact ND2-OE1 3.13Å; N265-Q268 WeakPolarHBondContact OD1-CG 3.27Å; N265-Q268 PolarHBondContact OD1-N 2.95Å; Q268-Q271 PolarHBondContact O-N 3.15Å; Q268-L272 WeakPolarHBondContact O-CB 3.48Å; Q268-L272 PolarHBondContact O-N 2.92Å
269A83.3Confident80.8Confident0 Ų063.9 Ų63.90%032%0.318CS..Hα-helixtrans-63.6-41.1174.900000112.4M264 N265 R266 S267 L273 L283M264-A269 HydrophobicContact CG-CB 3.91Å; N265-A269 WeakPolarHBondContact O-CB 3.43Å; N265-A269 PolarHBondContact O-N 2.77Å; R266-A269 PolarHBondContact O-N 3.41Å; S267-A269 VanDerWaalsContact C-N 3.31Å; S267-A269 PolarHBondContact O-N 3.33Å; A269-L273 VanDerWaalsContact O-CB 3.27Å; A269-L273 WeakPolarHBondContact O-CB 3.28Å; A269-L273 WeakPolarHBondContact O-CD1 3.19Å; A269-L273 WeakPolarHBondContact O-CG 3.38Å; A269-L273 PolarHBondContact O-N 3.07Å; A269-L283 HydrophobicContact CB-CD1 3.88Å; A269-L283 HydrophobicContact CB-CD2 4.17Å; A269-L283 HydrophobicContact CB-CG 4.43Å
270E88.3Confident80.5Confident43 Ų4363.1 Ų63.120%0.20132%0.315CS..Hα-helixtrans-65.3-42176.7-69.9-177.6-160.400111.6R266 S267 K274 C309 H311R266-E270 IonicContact CZ-OE1 3.45Å; R266-E270 IonicContact NE-OE1 3.17Å; R266-E270 PolarHBondContact NE-OE1 3.2Å; R266-E270 IonicContact NH2-OE1 2.77Å; R266-E270 PolarHBondContact NH2-OE1 3.36Å; R266-E270 WeakPolarHBondContact O-CG 3.36Å; R266-E270 PolarHBondContact O-N 3.15Å; S267-E270 PolarHBondContact O-N 3.2Å; S267-E270 VanDerWaalsContact O-N 3.1Å; E270-K274 VanDerWaalsContact O-CB 3.29Å; E270-K274 WeakPolarHBondContact O-CB 3.48Å; E270-K274 WeakPolarHBondContact O-CG 3.44Å; E270-K274 PolarHBondContact O-N 3.48Å; E270-C309 HydrophobicContact CB-CB 4.41Å; E270-C309 HydrophobicContact CG-CB 3.75Å; E270-H311 WeakPolarHBondContact CG-NE2 3.41Å; E270-H311 IonicContact OE1-CD2 3.05Å; E270-H311 IonicContact OE1-CE1 3.06Å; E270-H311 IonicContact OE1-NE2 3.49Å; E270-H311 PolarHBondContact OE1-NE2 2.65Å
271Q83.4Confident80.7Confident108 Ų10862.3 Ų62.351%0.50531%0.312SS..Hα-helixtrans-63.2-47.1177-176.3178.1-9.400111.6S267 Q268 K274 S275S267-Q271 PolarHBondContact O-N 3.13Å; Q268-Q271 PolarHBondContact O-N 3.15Å; Q271-K274 PolarHBondContact O-N 3.15Å; Q271-S275 WeakPolarHBondContact O-CB 3.47Å; Q271-S275 PolarHBondContact O-N 3.38Å; Q271-S275 PolarHBondContact O-OG 3.33Å
272L81.1Confident81.2Confident40 Ų4062.2 Ų62.221%0.20931%0.312CS..Hα-helixtrans-66.3-38.7179.8-174.164.3000112.3M264 Q268 S275 E276 L283 V355 N357M264-L272 HydrophobicContact CE-CD2 3.81Å; Q268-L272 WeakPolarHBondContact O-CB 3.48Å; Q268-L272 PolarHBondContact O-N 2.92Å; L272-S275 WeakPolarHBondContact CA-OG 3.41Å; L272-S275 PolarHBondContact O-OG 3.42Å; L272-E276 PolarHBondContact O-N 3.36Å; L272-L283 HydrophobicContact CD2-CD2 4.03Å; L272-V355 HydrophobicContact CD1-CG1 4.47Å; L272-V355 HydrophobicContact CD2-CG1 3.91Å; L272-V355 HydrophobicContact CG-CG1 3.6Å; L272-N357 HydrophobicContact CD2-CB 4.31Å
273L83.1Confident82Confident1 Ų157.9 Ų57.91%0.00529%0.293CS..Hα-helixtrans-66.1-42.5174.6-74.8170.3000111.5A269 N277 G281 L283 L298 V355A269-L273 VanDerWaalsContact O-CB 3.27Å; A269-L273 WeakPolarHBondContact O-CB 3.28Å; A269-L273 WeakPolarHBondContact O-CD1 3.19Å; A269-L273 WeakPolarHBondContact O-CG 3.38Å; A269-L273 PolarHBondContact O-N 3.07Å; L273-N277 PolarHBondContact O-N 3.48Å; L273-G281 WeakPolarHBondContact CD2-O 3.45Å; L273-L283 HydrophobicContact CD2-CD2 4.37Å; L273-L283 HydrophobicContact CG-CD2 4.11Å; L273-L298 HydrophobicContact CB-CB 4.24Å; L273-L298 WeakPolarHBondContact O-CD2 3.33Å; L273-V355 HydrophobicContact CD2-CB 3.87Å; L273-V355 HydrophobicContact CD2-CG1 4.14Å; L273-V355 HydrophobicContact CD2-CG2 3.84Å
274K81.3Confident83Confident100 Ų10050.9 Ų50.944%0.43526%0.255SS..Hα-helixtrans-69.7-33.7178.6-75.4172179.8172.10112.9E270 Q271 N277 L298E270-K274 VanDerWaalsContact O-CB 3.29Å; E270-K274 WeakPolarHBondContact O-CB 3.48Å; E270-K274 WeakPolarHBondContact O-CG 3.44Å; E270-K274 PolarHBondContact O-N 3.48Å; Q271-K274 PolarHBondContact O-N 3.15Å; K274-N277 WeakPolarHBondContact O-CB 3.35Å; K274-N277 PolarHBondContact O-N 2.86Å; K274-L298 HydrophobicContact CG-CD1 4.24Å
275S78.3Confident83.4Confident85 Ų8550.8 Ų50.859%0.59425%0.254SS*.Hα-helixtrans-67.3-42.4176.265.10000111.8Q271 L272 N277Q271-S275 WeakPolarHBondContact O-CB 3.47Å; Q271-S275 PolarHBondContact O-N 3.38Å; Q271-S275 PolarHBondContact O-OG 3.33Å; L272-S275 WeakPolarHBondContact CA-OG 3.41Å; L272-S275 PolarHBondContact O-OG 3.42Å; S275-N277 VanDerWaalsContact C-N 3.28Å; S275-N277 PolarHBondContact O-N 3.24Å
276E74.8Confident83.3Confident85 Ų8549.6 Ų49.640%0.39725%0.248SC..Hα-helixtrans-68.3-28.7173.7-78.7-66.3137.500112.6L272 K278 V355L272-E276 PolarHBondContact O-N 3.36Å; E276-K278 VanDerWaalsContact C-N 3.31Å; E276-K278 WeakPolarHBondContact O-CG 3.49Å; E276-K278 PolarHBondContact O-N 3.22Å; E276-K278 IonicContact OE2-NZ 2.69Å; E276-K278 PolarHBondContact OE2-NZ 2.88Å; E276-V355 HydrophobicContact CB-CG1 4.49Å; E276-V355 HydrophobicContact CB-CG2 4.03Å; E276-V355 HydrophobicContact CG-CG1 3.94Å; E276-V355 HydrophobicContact CG-CG2 4.07Å
277N76.5Confident83.2Confident73 Ų7343.7 Ų43.739%0.3923%0.228SC..THydrogen-bonded Turntrans51.941.4170.6-161.413.7000114.4L273 K274 S275 K300L273-N277 PolarHBondContact O-N 3.48Å; K274-N277 WeakPolarHBondContact O-CB 3.35Å; K274-N277 PolarHBondContact O-N 2.86Å; S275-N277 VanDerWaalsContact C-N 3.28Å; S275-N277 PolarHBondContact O-N 3.24Å; N277-K300 VanDerWaalsContact CG-NZ 3.29Å; N277-K300 WeakPolarHBondContact O-CE 3.4Å; N277-K300 PolarHBondContact O-NZ 3.24Å; N277-K300 WeakPolarHBondContact OD1-CE 3.31Å; N277-K300 PolarHBondContact OD1-NZ 3.35Å
278K76.1Confident82.9Confident90 Ų9045.6 Ų45.639%0.39124%0.242SC..  trans-108.4128179.1-72.8165.1-172.41540111.1E276 G280 G281 H353E276-K278 VanDerWaalsContact C-N 3.31Å; E276-K278 WeakPolarHBondContact O-CG 3.49Å; E276-K278 PolarHBondContact O-N 3.22Å; E276-K278 IonicContact OE2-NZ 2.69Å; E276-K278 PolarHBondContact OE2-NZ 2.88Å; K278-G280 PolarHBondContact O-N 2.86Å; K278-G281 PolarHBondContact O-N 3.2Å; K278-H353 HydrophobicContact CB-CB 4.25Å; K278-H353 HydrophobicContact CD-CB 4.18Å
279D80.6Confident82.4Confident47 Ų4748.7 Ų48.725%0.25125%0.254SS..THydrogen-bonded Turntrans-64.5128.6174.717965.8000110.4G281 T299 K300 K352 H353D279-G281 VanDerWaalsContact C-N 3.27Å; D279-T299 WeakPolarHBondContact OD1-CA 3.37Å; D279-T299 PolarHBondContact OD1-OG1 2.83Å; D279-K300 HydrophobicContact CB-CB 4.14Å; D279-K300 HydrophobicContact CB-CD 4.17Å; D279-K300 HydrophobicContact CB-CG 4.03Å; D279-K300 PolarHBondContact OD1-N 3.08Å; D279-K352 IonicContact OD2-NZ 2.77Å; D279-K352 PolarHBondContact OD2-NZ 2.91Å; D279-H353 PolarHBondContact O-CD2 3.3Å; D279-H353 VanDerWaalsContact O-CD2 3.29Å
280G79.3Confident81.8Confident0 Ų053.9 Ų53.90%030%0.296CS..THydrogen-bonded Turntrans75.714.3-171.200000113.8K278 L298 K352 H353K278-G280 PolarHBondContact O-N 2.86Å; G280-L298 WeakPolarHBondContact CA-O 3.28Å; G280-L298 PolarHBondContact N-O 2.75Å; G280-K352 PolarHBondContact O-N 3.37Å; G280-H353 PolarHBondContact O-N 3.04Å
281G86.3Confident80.9Confident1 Ų155 Ų551%0.0132%0.32CS..EExtended strand (participates in β ladder)trans-64.4132.5169.900000111L273 K278 D279 L297 L298 H353L273-G281 WeakPolarHBondContact CD2-O 3.45Å; K278-G281 PolarHBondContact O-N 3.2Å; D279-G281 VanDerWaalsContact C-N 3.27Å; G281-L297 CarbonylContact O-C 3.58Å; G281-L297 WeakPolarHBondContact O-CA 3.32Å; G281-L297 WeakPolarHBondContact O-CD1 3.41Å; G281-L298 PolarHBondContact O-N 2.65Å; G281-H353 CarbonylContact C-O 3.46Å; G281-H353 VanDerWaalsContact CA-O 3.26Å; G281-H353 WeakPolarHBondContact CA-O 3.28Å
282F92Very high80.8Confident0 Ų054.3 Ų54.30%032%0.315CS..EExtended strand (participates in β ladder)trans-146.7155.2-174.680.4-79.4000114.1W259 I284 S296 L297 I337 Q341 L351 H353 I354 V355W259-F282 HydrophobicContact CB-CE2 3.92Å; W259-F282 HydrophobicContact CB-CZ 4.32Å; W259-F282 HydrophobicContact CG-CE2 4.31Å; F282-I284 HydrophobicContact CD2-CD1 3.78Å; F282-I284 HydrophobicContact CE2-CD1 3.7Å; F282-S296 WeakPolarHBondContact CA-O 3.37Å; F282-L297 HydrophobicContact CB-CD1 4.1Å; F282-I337 HydrophobicContact CE2-CG2 3.75Å; F282-I337 HydrophobicContact CZ-CG2 4.07Å; F282-Q341 HydrophobicContact CE1-CG 4.46Å; F282-Q341 HydrophobicContact CZ-CG 4.24Å; F282-L351 HydrophobicContact CB-CD2 3.68Å; F282-L351 HydrophobicContact CD1-CB 3.6Å; F282-L351 HydrophobicContact CD1-CD2 4.29Å; F282-L351 HydrophobicContact CD1-CG 4.41Å; F282-L351 HydrophobicContact CD2-CB 4.19Å; F282-L351 HydrophobicContact CD2-CD1 3.91Å; F282-L351 HydrophobicContact CD2-CD2 4.01Å; F282-L351 HydrophobicContact CD2-CG 4.26Å; F282-L351 HydrophobicContact CE1-CB 3.7Å; F282-L351 HydrophobicContact CE2-CB 4.29Å; F282-L351 HydrophobicContact CE2-CD1 3.97Å; F282-L351 HydrophobicContact CG-CB 3.86Å; F282-L351 HydrophobicContact CG-CD1 4.33Å; F282-L351 HydrophobicContact CG-CD2 3.73Å; F282-L351 HydrophobicContact CG-CG 4.17Å; F282-L351 HydrophobicContact CZ-CB 4.06Å; F282-L351 HydrophobicContact CZ-CD1 4.44Å; F282-H353 WeakPolarHBondContact CD1-O 3.27Å; F282-H353 PolarHBondContact N-O 3.39Å; F282-I354 HydrophobicContact CE1-CG1 3.84Å; F282-I354 HydrophobicContact CZ-CG1 3.77Å; F282-V355 PolarHBondContact O-N 2.89Å
283L92.1Very high81.2Confident0 Ų055.1 Ų55.10%032%0.316CS..EExtended strand (participates in β ladder)trans-149.5160.217167.984000110.9W259 M264 A269 L272 L273 R285 S296 V355W259-L283 CarbonylContact O-C 3.53Å; M264-L283 HydrophobicContact CG-CD1 4.39Å; A269-L283 HydrophobicContact CB-CD1 3.88Å; A269-L283 HydrophobicContact CB-CD2 4.17Å; A269-L283 HydrophobicContact CB-CG 4.43Å; L272-L283 HydrophobicContact CD2-CD2 4.03Å; L273-L283 HydrophobicContact CD2-CD2 4.37Å; L273-L283 HydrophobicContact CG-CD2 4.11Å; L283-R285 HydrophobicContact CD1-CB 4.2Å; L283-R285 HydrophobicContact CD1-CG 4.33Å; L283-S296 PolarHBondContact N-O 2.86Å; L283-S296 PolarHBondContact O-N 3.46Å; L283-V355 VanDerWaalsContact CB-O 3.3Å; L283-V355 WeakPolarHBondContact CB-O 3.3Å; L283-V355 HydrophobicContact CD2-CG1 4.27Å
284I90.8Very high81.6Confident0 Ų055.1 Ų55.10%032%0.316CS..EExtended strand (participates in β ladder)trans-115.5137.7177.2-62.881.9000108.2W259 Y260 C261 F282 T294 V295 I314 I337W259-I284 HydrophobicContact CB-CD1 3.94Å; W259-I284 HydrophobicContact CD2-CD1 3.69Å; W259-I284 HydrophobicContact CE3-CB 3.72Å; W259-I284 HydrophobicContact CE3-CD1 3.2Å; W259-I284 HydrophobicContact CE3-CG1 3.66Å; W259-I284 HydrophobicContact CG-CD1 4.04Å; W259-I284 HydrophobicContact CZ3-CB 3.94Å; W259-I284 HydrophobicContact CZ3-CD1 3.9Å; W259-I284 HydrophobicContact CZ3-CG1 3.92Å; W259-I284 HydrophobicContact CZ3-CG2 4.25Å; W259-I284 PolarHBondContact O-N 3.48Å; Y260-I284 CarbonylContact C-O 3.6Å; Y260-I284 WeakPolarHBondContact CA-O 3.42Å; Y260-I284 HydrophobicContact CD2-CB 4.12Å; Y260-I284 HydrophobicContact CD2-CG2 3.78Å; Y260-I284 HydrophobicContact CE2-CG2 4.17Å; C261-I284 PolarHBondContact N-O 3.03Å; F282-I284 HydrophobicContact CD2-CD1 3.78Å; F282-I284 HydrophobicContact CE2-CD1 3.7Å; I284-T294 WeakPolarHBondContact CA-O 3.34Å; I284-V295 HydrophobicContact CG1-CG2 3.97Å; I284-I314 HydrophobicContact CG2-CD1 4.43Å; I284-I337 HydrophobicContact CD1-CD1 3.55Å; I284-I337 HydrophobicContact CD1-CG1 4Å; I284-I337 HydrophobicContact CG1-CD1 3.74Å; I284-I337 HydrophobicContact CG1-CG1 4.33Å
285R89.7Confident82.1Confident17 Ų1750.3 Ų50.36%0.06430%0.295CS..EExtended strand (participates in β ladder)trans-140.8165.9-179.259.6179.1-178.875.5-0.6111.1C261 M264 L283 S287 Y293 T294 S296C261-R285 WeakPolarHBondContact O-CA 3.38Å; C261-R285 WeakPolarHBondContact O-CB 3.36Å; M264-R285 HydrophobicContact CB-CB 3.89Å; M264-R285 VanDerWaalsContact O-CD 3.26Å; M264-R285 WeakPolarHBondContact O-CD 3.49Å; L283-R285 HydrophobicContact CD1-CB 4.2Å; L283-R285 HydrophobicContact CD1-CG 4.33Å; R285-S287 PolarHBondContact O-N 3.02Å; R285-Y293 WeakPolarHBondContact O-CA 3.27Å; R285-T294 PolarHBondContact N-O 2.88Å; R285-T294 PolarHBondContact O-N 3.36Å; R285-S296 PolarHBondContact NE-OG 2.86Å
286D83.6Confident82.8Confident53 Ų5346.3 Ų46.328%0.28327%0.267SS..EExtended strand (participates in β ladder)trans-60.5137.5167.8-76.7-28.2000110.4Y260 K262 Y293Y260-D286 PolarHBondContact OH-OD1 2.85Å; K262-D286 WeakPolarHBondContact CG-OD2 3.41Å; K262-D286 WeakPolarHBondContact O-CB 3.41Å; D286-Y293 WeakPolarHBondContact OD1-CE1 3.35Å
287S81.8Confident83.5Confident18 Ų1842.2 Ų42.213%0.12625%0.248CC..  trans-75.3157.8170.9-163.90000109.3R285 K289 K292 T294R285-S287 PolarHBondContact O-N 3.02Å; S287-K289 PolarHBondContact O-N 2.86Å; S287-K289 VanDerWaalsContact O-N 3.07Å; S287-K292 WeakPolarHBondContact CA-O 3.43Å; S287-K292 WeakPolarHBondContact CB-O 3.32Å; S287-K292 PolarHBondContact N-O 3.26Å; S287-T294 WeakPolarHBondContact CA-OG1 3.26Å; S287-T294 WeakPolarHBondContact CB-OG1 3.41Å; S287-T294 PolarHBondContact OG-OG1 2.77Å
288S75.3Confident84.1Confident124 Ų12438.8 Ų38.887%0.86723%0.229SC*.SBendtrans-63.5-12.5171.2520000113
289K73.2Confident84.4Confident138 Ų13835.2 Ų35.260%0.622%0.215SC*.SBendtrans-95.2123.3170.3-63.4-177.4-179.4-177.90109.3S287 G291 K292S287-K289 PolarHBondContact O-N 2.86Å; S287-K289 VanDerWaalsContact O-N 3.07Å; K289-G291 PolarHBondContact O-N 3.37Å; K289-K292 HydrophobicContact CB-CB 4.44Å; K289-K292 HydrophobicContact CB-CD 4.24Å; K289-K292 HydrophobicContact CB-CG 4.45Å; K289-K292 HydrophobicContact CD-CD 4.45Å; K289-K292 PolarHBondContact O-N 3.26Å; K289-K292 VanDerWaalsContact O-N 3.15Å
290A69.5Low84.2Confident108 Ų10837.5 Ų37.589%0.89322%0.223SC*.THydrogen-bonded Turntrans-52.2131.6179.100000111.7K292A290-K292 VanDerWaalsContact C-N 3.34Å; A290-K292 PolarHBondContact O-N 3.26Å
291G69.4Low83.2Confident67 Ų6741.2 Ų41.269%0.69126%0.261SS*.THydrogen-bonded Turntrans76.212.6178.700000115.6K289K289-G291 PolarHBondContact O-N 3.37Å
292K83.1Confident81.9Confident94 Ų9443.8 Ų43.841%0.40929%0.287SS..  trans-118.7156.1173.2-64-167.3175.9-166.30111S287 K289 A290S287-K292 WeakPolarHBondContact CA-O 3.43Å; S287-K292 WeakPolarHBondContact CB-O 3.32Å; S287-K292 PolarHBondContact N-O 3.26Å; K289-K292 HydrophobicContact CB-CB 4.44Å; K289-K292 HydrophobicContact CB-CD 4.24Å; K289-K292 HydrophobicContact CB-CG 4.45Å; K289-K292 HydrophobicContact CD-CD 4.45Å; K289-K292 PolarHBondContact O-N 3.26Å; K289-K292 VanDerWaalsContact O-N 3.15Å; A290-K292 VanDerWaalsContact C-N 3.34Å; A290-K292 PolarHBondContact O-N 3.26Å
293Y89.3Confident79.9Confident56 Ų5651.3 Ų51.322%0.2233%0.333CS..EExtended strand (participates in β ladder)trans-120.2155.4-177.4-55.7-77.2000111.4L254 Y260 R285 D286 I314 I333L254-Y293 HydrophobicContact CD1-CD1 4.26Å; L254-Y293 HydrophobicContact CD1-CE1 3.79Å; L254-Y293 HydrophobicContact CD1-CE2 4.18Å; Y260-Y293 AromaticContact CE2-CD1 3.77Å; Y260-Y293 HydrophobicContact CE2-CD1 3.77Å; Y260-Y293 AromaticContact CE2-CE1 3.89Å; Y260-Y293 HydrophobicContact CE2-CE1 3.89Å; Y260-Y293 AromaticContact CZ-CE1 3.99Å; Y260-Y293 WeakPolarHBondContact OH-CE1 3.4Å; R285-Y293 WeakPolarHBondContact O-CA 3.27Å; D286-Y293 WeakPolarHBondContact OD1-CE1 3.35Å; Y293-I314 PolarHBondContact O-N 3.23Å; Y293-I333 HydrophobicContact CD2-CD1 3.25Å; Y293-I333 HydrophobicContact CE2-CD1 3.42Å; Y293-I333 VanDerWaalsContact CE2-CD1 3.42Å; Y293-I333 HydrophobicContact CG-CD1 3.96Å
294T90.6Very high78.2Confident1 Ų158.1 Ų58.11%0.00637%0.365CS..EExtended strand (participates in β ladder)trans-131.2128.6179.8-47.40000110.8I284 R285 S287 H311 Y312 N313I284-T294 WeakPolarHBondContact CA-O 3.34Å; R285-T294 PolarHBondContact N-O 2.88Å; R285-T294 PolarHBondContact O-N 3.36Å; S287-T294 WeakPolarHBondContact CA-OG1 3.26Å; S287-T294 WeakPolarHBondContact CB-OG1 3.41Å; S287-T294 PolarHBondContact OG-OG1 2.77Å; T294-H311 HydrophobicContact CG2-CB 3.93Å; T294-Y312 CarbonylContact C-O 3.44Å; T294-Y312 WeakPolarHBondContact CA-O 3.48Å; T294-N313 PolarHBondContact OG1-OD1 3.03Å
295V92.1Very high76.5Confident0 Ų065.8 Ų65.80%041%0.412CS..EExtended strand (participates in β ladder)trans-87.8121.7168.6-175.20000108.9I284 H311 Y312 I314 L324 I337 M347 L351I284-V295 HydrophobicContact CG1-CG2 3.97Å; V295-H311 CarbonylContact O-C 3.58Å; V295-H311 WeakPolarHBondContact O-CA 3.49Å; V295-Y312 PolarHBondContact N-O 2.9Å; V295-Y312 PolarHBondContact O-N 3.05Å; V295-I314 HydrophobicContact CG2-CD1 3.88Å; V295-I314 HydrophobicContact CG2-CG1 3.93Å; V295-L324 HydrophobicContact CG2-CD1 3.86Å; V295-L324 HydrophobicContact CG2-CD2 4.01Å; V295-L324 HydrophobicContact CG2-CG 4.48Å; V295-I337 HydrophobicContact CG2-CD1 3.95Å; V295-M347 HydrophobicContact CG1-CE 4.4Å; V295-L351 HydrophobicContact CG1-CD2 4.03Å
296S92.4Very high75.1Confident0 Ų066.7 Ų66.70%043%0.427CS..EExtended strand (participates in β ladder)trans-104.8128.3174-52.90000108.6F282 L283 R285 R310 H311F282-S296 WeakPolarHBondContact CA-O 3.37Å; L283-S296 PolarHBondContact N-O 2.86Å; L283-S296 PolarHBondContact O-N 3.46Å; R285-S296 PolarHBondContact NE-OG 2.86Å; S296-R310 WeakPolarHBondContact CA-O 3.28Å; S296-H311 WeakPolarHBondContact CB-ND1 3.34Å; S296-H311 PolarHBondContact OG-ND1 3.06Å
297L90.1Very high74.4Confident0 Ų064.6 Ų64.60%042%0.417CS..EExtended strand (participates in β ladder)trans-133.3130.3-171173.563.6000110.7G281 F282 C309 R310 Y312 M347 V348 S349 L351G281-L297 CarbonylContact O-C 3.58Å; G281-L297 WeakPolarHBondContact O-CA 3.32Å; G281-L297 WeakPolarHBondContact O-CD1 3.41Å; F282-L297 HydrophobicContact CB-CD1 4.1Å; L297-C309 CarbonylContact O-C 3.57Å; L297-C309 WeakPolarHBondContact O-CA 3.45Å; L297-R310 PolarHBondContact N-O 3.43Å; L297-R310 PolarHBondContact O-N 2.93Å; L297-Y312 HydrophobicContact CB-CE2 4.31Å; L297-Y312 HydrophobicContact CD2-CE2 4.16Å; L297-M347 HydrophobicContact CD2-CE 3.78Å; L297-V348 HydrophobicContact CD2-CG1 3.72Å; L297-V348 HydrophobicContact CG-CG1 4.35Å; L297-S349 WeakPolarHBondContact CD2-O 3.23Å; L297-L351 HydrophobicContact CD1-CD2 4.01Å; L297-L351 HydrophobicContact CD2-CD2 4.38Å
298L88.4Confident74.4Confident0 Ų065.6 Ų65.60%042%0.424CS..EExtended strand (participates in β ladder)trans-94.3135.1171.6-173.372.8000111.2L273 K274 G280 G281 C309L273-L298 HydrophobicContact CB-CB 4.24Å; L273-L298 WeakPolarHBondContact O-CD2 3.33Å; K274-L298 HydrophobicContact CG-CD1 4.24Å; G280-L298 WeakPolarHBondContact CA-O 3.28Å; G280-L298 PolarHBondContact N-O 2.75Å; G281-L298 PolarHBondContact O-N 2.65Å; L298-C309 VanDerWaalsContact CD1-SG 3.53Å
299T82.4Confident74.9Confident15 Ų1560.4 Ų60.49%0.09239%0.388CS..EExtended strand (participates in β ladder)trans-128.9142.6170.4-176.50000112.2D279 G301 G307 S308 V348D279-T299 WeakPolarHBondContact OD1-CA 3.37Å; D279-T299 PolarHBondContact OD1-OG1 2.83Å; T299-G301 PolarHBondContact OG1-N 3.07Å; T299-G307 CarbonylContact O-C 3.59Å; T299-G307 VanDerWaalsContact O-CA 3.26Å; T299-G307 WeakPolarHBondContact O-CA 3.04Å; T299-S308 WeakPolarHBondContact CG2-O 3.48Å; T299-S308 PolarHBondContact N-O 2.89Å; T299-S308 PolarHBondContact O-N 3.29Å; T299-V348 HydrophobicContact CG2-CB 4.44Å; T299-V348 HydrophobicContact CG2-CG1 3.82Å; T299-V348 HydrophobicContact CG2-CG2 3.73Å
300K76.3Confident75.6Confident96 Ų9660.3 Ų60.342%0.41738%0.383SS..  trans-98.59.3177.9-68.9-171.3167-173.60114.2N277 D279 G302N277-K300 VanDerWaalsContact CG-NZ 3.29Å; N277-K300 WeakPolarHBondContact O-CE 3.4Å; N277-K300 PolarHBondContact O-NZ 3.24Å; N277-K300 WeakPolarHBondContact OD1-CE 3.31Å; N277-K300 PolarHBondContact OD1-NZ 3.35Å; D279-K300 HydrophobicContact CB-CB 4.14Å; D279-K300 HydrophobicContact CB-CD 4.17Å; D279-K300 HydrophobicContact CB-CG 4.03Å; D279-K300 PolarHBondContact OD1-N 3.08Å; K300-G302 PolarHBondContact O-N 3.2Å; K300-G302 VanDerWaalsContact O-N 3.09Å
301G58.5Low76.5Confident77 Ų7757.2 Ų57.279%0.79435%0.35SS*.  trans-78.623.5-174.800000116.9T299T299-G301 PolarHBondContact OG1-N 3.07Å
302G58.7Low77.5Confident55 Ų5556.4 Ų56.457%0.56733%0.327SS*.SBendtrans-131.6172.6-173.600000114.6K300 E304K300-G302 PolarHBondContact O-N 3.2Å; K300-G302 VanDerWaalsContact O-N 3.09Å; G302-E304 PolarHBondContact O-N 2.89Å
303V50.2Low77.7Confident159 Ų15956.3 Ų56.396%0.96433%0.331SS*.SBendtrans-68.9-12.1-174.9-170.20000113.4
304E56.5Low77.7Confident142 Ų14253.7 Ų53.766%0.66432%0.321SS*.SBendtrans-86.6130.4-177.6-67.2178.8169.500112.5G302 G306 G307G302-E304 PolarHBondContact O-N 2.89Å; E304-G306 PolarHBondContact O-N 2.73Å; E304-G307 PolarHBondContact O-N 2.91Å
305T55.9Low77.5Confident162 Ų16255.7 Ų55.799%0.99433%0.334SS*.THydrogen-bonded Turntrans-65.20.9-176.841.10000115.6
306G58.8Low77.2Confident36 Ų3658.9 Ų58.937%0.37135%0.354SS..THydrogen-bonded Turntrans-123.81.1-177.300000116.4E304E304-G306 PolarHBondContact O-N 2.73Å
307G69.8Low76.8Confident8 Ų859.6 Ų59.68%0.08236%0.358CS..  trans73.2151-173.800000113.9T299 E304T299-G307 CarbonylContact O-C 3.59Å; T299-G307 VanDerWaalsContact O-CA 3.26Å; T299-G307 WeakPolarHBondContact O-CA 3.04Å; E304-G307 PolarHBondContact O-N 2.91Å
308S81.4Confident76.3Confident39 Ų3965.8 Ų65.827%0.27340%0.398SS..EExtended strand (participates in β ladder)trans-104.4129.2-176.2-174.20000111.2T299T299-S308 WeakPolarHBondContact CG2-O 3.48Å; T299-S308 PolarHBondContact N-O 2.89Å; T299-S308 PolarHBondContact O-N 3.29Å
309C86.3Confident76Confident16 Ų1672.7 Ų72.711%0.10843%0.431CS..EExtended strand (participates in β ladder)trans-86.3131.1174.6-65.80000111.1E270 L297 L298E270-C309 HydrophobicContact CB-CB 4.41Å; E270-C309 HydrophobicContact CG-CB 3.75Å; L297-C309 CarbonylContact O-C 3.57Å; L297-C309 WeakPolarHBondContact O-CA 3.45Å; L298-C309 VanDerWaalsContact CD1-SG 3.53Å
310R87.8Confident75.9Confident135 Ų13574 Ų7451%0.50945%0.446SS..EExtended strand (participates in β ladder)trans-118.7140.4174.3-64.5-63.3-174.3164.7-1109.9S296 L297 Y312 V348S296-R310 WeakPolarHBondContact CA-O 3.28Å; L297-R310 PolarHBondContact N-O 3.43Å; L297-R310 PolarHBondContact O-N 2.93Å; R310-Y312 HydrophobicContact CB-CD2 4.48Å; R310-Y312 HydrophobicContact CB-CE2 3.62Å; R310-V348 HydrophobicContact CB-CG1 4.27Å; R310-V348 HydrophobicContact CG-CB 4.46Å; R310-V348 HydrophobicContact CG-CG1 3.89Å
311H89.2Confident76.4Confident43 Ų4372.1 Ų72.120%0.19944%0.439CS..EExtended strand (participates in β ladder)trans-119.7127.9179.1-54.5-84.2000110.2R266 E270 T294 V295 S296R266-H311 PolarHBondContact NE-CD2 3.42Å; R266-H311 VanDerWaalsContact NE-CD2 3.33Å; R266-H311 PolarHBondContact NE-NE2 3.17Å; E270-H311 WeakPolarHBondContact CG-NE2 3.41Å; E270-H311 IonicContact OE1-CD2 3.05Å; E270-H311 IonicContact OE1-CE1 3.06Å; E270-H311 IonicContact OE1-NE2 3.49Å; E270-H311 PolarHBondContact OE1-NE2 2.65Å; T294-H311 HydrophobicContact CG2-CB 3.93Å; V295-H311 CarbonylContact O-C 3.58Å; V295-H311 WeakPolarHBondContact O-CA 3.49Å; S296-H311 WeakPolarHBondContact CB-ND1 3.34Å; S296-H311 PolarHBondContact OG-ND1 3.06Å
312Y88.9Confident77.8Confident51 Ų5170.6 Ų70.620%0.241%0.411CS..EExtended strand (participates in β ladder)trans-119.9122.6-179.5-56.6-92.9000109.1T294 V295 L297 R310 M347 V348T294-Y312 CarbonylContact C-O 3.44Å; T294-Y312 WeakPolarHBondContact CA-O 3.48Å; V295-Y312 PolarHBondContact N-O 2.9Å; V295-Y312 PolarHBondContact O-N 3.05Å; L297-Y312 HydrophobicContact CB-CE2 4.31Å; L297-Y312 HydrophobicContact CD2-CE2 4.16Å; R310-Y312 HydrophobicContact CB-CD2 4.48Å; R310-Y312 HydrophobicContact CB-CE2 3.62Å; Y312-M347 HydrophobicContact CD1-CG 4.44Å; Y312-M347 HydrophobicContact CD2-CE 3.66Å; Y312-M347 HydrophobicContact CE1-CB 4.47Å; Y312-M347 HydrophobicContact CE1-CG 4.22Å; Y312-M347 HydrophobicContact CE2-CE 3.76Å; Y312-M347 HydrophobicContact CG-CE 4.21Å; Y312-V348 WeakPolarHBondContact OH-CB 3.38Å; Y312-V348 WeakPolarHBondContact OH-CG1 3.34Å; Y312-V348 PolarHBondContact OH-N 2.77Å
313N88.9Confident79Confident91 Ų9170.3 Ų70.349%0.48739%0.393SS..EExtended strand (participates in β ladder)trans-77.1132176.9-67-45000109.7T294 C315T294-N313 PolarHBondContact OG1-OD1 3.03Å; N313-C315 PolarHBondContact O-N 3.32Å
314I89.1Confident80.6Confident2 Ų264 Ų641%0.0135%0.354CS..EExtended strand (participates in β ladder)trans-76.8112.7169.4-55-174.3000107.2I284 Y293 V295 F322 L324 I333 L336I284-I314 HydrophobicContact CG2-CD1 4.43Å; Y293-I314 PolarHBondContact O-N 3.23Å; V295-I314 HydrophobicContact CG2-CD1 3.88Å; V295-I314 HydrophobicContact CG2-CG1 3.93Å; I314-F322 HydrophobicContact CG2-CB 3.94Å; I314-F322 HydrophobicContact CG2-CD1 3.86Å; I314-F322 HydrophobicContact CG2-CG 4.33Å; I314-L324 HydrophobicContact CG1-CD2 3.84Å; I314-L324 HydrophobicContact CG1-CG 4.36Å; I314-I333 HydrophobicContact CD1-CG1 4.36Å; I314-I333 HydrophobicContact CD1-CG2 3.9Å; I314-I333 HydrophobicContact CG2-CG1 4.43Å; I314-L336 HydrophobicContact CD1-CD2 4.47Å; I314-L336 HydrophobicContact CG2-CD1 3.95Å
315C86.2Confident81.4Confident42 Ų4258.4 Ų58.428%0.28433%0.332SS..EExtended strand (participates in β ladder)trans-92.2154177.7-70.40000110.4N313 F322 Y323N313-C315 PolarHBondContact O-N 3.32Å; C315-F322 CarbonylContact O-C 3.57Å; C315-F322 VanDerWaalsContact O-CA 3.31Å; C315-F322 WeakPolarHBondContact O-CA 3.49Å; C315-Y323 HydrophobicContact CB-CD1 3.96Å; C315-Y323 HydrophobicContact CB-CD2 4.12Å; C315-Y323 HydrophobicContact CB-CE1 3.45Å; C315-Y323 VanDerWaalsContact CB-CE1 3.45Å; C315-Y323 HydrophobicContact CB-CE2 3.63Å; C315-Y323 HydrophobicContact CB-CG 4.28Å; C315-Y323 PolarHBondContact N-O 2.91Å; C315-Y323 WeakPolarHBondContact O-CD1 3.38Å; C315-Y323 PolarHBondContact O-N 3.34Å
316T84.4Confident81.8Confident67 Ų6758.5 Ų58.541%0.41132%0.321SS..EExtended strand (participates in β ladder)trans-119.1130.6177.9-48.20000109Q321 F322T316-Q321 CarbonylContact C-O 3.4Å; T316-Q321 VanDerWaalsContact CA-O 3.24Å; T316-Q321 WeakPolarHBondContact CA-O 3.45Å; T316-F322 HydrophobicContact CG2-CE1 4.46Å
317T84.6Confident82.4Confident15 Ų1565.9 Ų65.99%0.09234%0.343CS..  trans-72.8161.7174.465.90000110.6Q319 G320 Q321 Y323T317-Q319 PolarHBondContact O-N 2.85Å; T317-Q319 PolarHBondContact OG1-N 3.07Å; T317-G320 PolarHBondContact O-N 3.31Å; T317-Q321 HydrophobicContact CG2-CB 4.4Å; T317-Q321 PolarHBondContact N-O 3.21Å; T317-Q321 WeakPolarHBondContact OG1-CB 3.45Å; T317-Q321 PolarHBondContact OG1-N 2.87Å; T317-Q321 VanDerWaalsContact OG1-N 3.1Å; T317-Q321 PolarHBondContact OG1-O 2.8Å; T317-Y323 HydrophobicContact CG2-CD1 3.69Å; T317-Y323 HydrophobicContact CG2-CE1 3.7Å
318P79.9Confident82.8Confident130 Ų13069.1 Ų69.184%0.84436%0.355SS*.THydrogen-bonded Turntrans-55.9-22.5172.8-25.835.2000114.1G320P318-G320 VanDerWaalsContact C-N 3.32Å
319Q81.4Confident83.1Confident146 Ų14671.4 Ų71.468%0.68236%0.362SS*.THydrogen-bonded Turntrans-87.43.8177.2-60.675.916.200113.3T317T317-Q319 PolarHBondContact O-N 2.85Å; T317-Q319 PolarHBondContact OG1-N 3.07Å
320G80.9Confident83.2Confident41 Ų4171.9 Ų71.942%0.42336%0.362SS..SBendtrans8510.3176.700000115.4T317 P318T317-G320 PolarHBondContact O-N 3.31Å; P318-G320 VanDerWaalsContact C-N 3.32Å
321Q87.1Confident83Confident58 Ų5870.3 Ų70.327%0.27136%0.364SS..  trans-90.1144.9-179.9-58.2-178-60.900111.5T316 T317 H329 F330 N331T316-Q321 CarbonylContact C-O 3.4Å; T316-Q321 VanDerWaalsContact CA-O 3.24Å; T316-Q321 WeakPolarHBondContact CA-O 3.45Å; T317-Q321 HydrophobicContact CG2-CB 4.4Å; T317-Q321 PolarHBondContact N-O 3.21Å; T317-Q321 WeakPolarHBondContact OG1-CB 3.45Å; T317-Q321 PolarHBondContact OG1-N 2.87Å; T317-Q321 VanDerWaalsContact OG1-N 3.1Å; T317-Q321 PolarHBondContact OG1-O 2.8Å; Q321-H329 HydrophobicContact CB-CB 4.06Å; Q321-F330 CarbonylContact C-O 3.49Å; Q321-F330 VanDerWaalsContact CA-O 3.29Å; Q321-F330 WeakPolarHBondContact CA-O 3.38Å; Q321-F330 WeakPolarHBondContact CB-O 3.49Å; Q321-N331 PolarHBondContact NE2-OD1 3.44Å
322F86.9Confident82.8Confident44 Ų4471 Ų7119%0.19337%0.371CS..EExtended strand (participates in β ladder)trans-93.3142.3-179-59.1-81.6000111.9I314 C315 T316 F330 I333 L336I314-F322 HydrophobicContact CG2-CB 3.94Å; I314-F322 HydrophobicContact CG2-CD1 3.86Å; I314-F322 HydrophobicContact CG2-CG 4.33Å; C315-F322 CarbonylContact O-C 3.57Å; C315-F322 VanDerWaalsContact O-CA 3.31Å; C315-F322 WeakPolarHBondContact O-CA 3.49Å; T316-F322 HydrophobicContact CG2-CE1 4.46Å; F322-F330 PolarHBondContact N-O 3.05Å; F322-F330 WeakPolarHBondContact O-CD2 3.32Å; F322-F330 PolarHBondContact O-N 2.88Å; F322-I333 HydrophobicContact CB-CG1 4.41Å; F322-I333 HydrophobicContact CD1-CD1 4.11Å; F322-I333 HydrophobicContact CD1-CG1 3.84Å; F322-I333 HydrophobicContact CD2-CG1 4.11Å; F322-I333 HydrophobicContact CE1-CD1 3.94Å; F322-I333 HydrophobicContact CE1-CG1 4.09Å; F322-I333 HydrophobicContact CE2-CG1 4.36Å; F322-I333 HydrophobicContact CG-CG1 3.84Å; F322-I333 HydrophobicContact CZ-CD1 4.26Å; F322-I333 HydrophobicContact CZ-CG1 4.34Å; F322-L336 HydrophobicContact CB-CD1 3.85Å
323Y85.8Confident82.6Confident50 Ų5069 Ų6920%0.19636%0.364CS..EExtended strand (participates in β ladder)trans-150.1151.2174.167.9-82.4000112.7C315 T317 E326 H328 H329C315-Y323 HydrophobicContact CB-CD1 3.96Å; C315-Y323 HydrophobicContact CB-CD2 4.12Å; C315-Y323 HydrophobicContact CB-CE1 3.45Å; C315-Y323 VanDerWaalsContact CB-CE1 3.45Å; C315-Y323 HydrophobicContact CB-CE2 3.63Å; C315-Y323 HydrophobicContact CB-CG 4.28Å; C315-Y323 PolarHBondContact N-O 2.91Å; C315-Y323 WeakPolarHBondContact O-CD1 3.38Å; C315-Y323 PolarHBondContact O-N 3.34Å; T317-Y323 HydrophobicContact CG2-CD1 3.69Å; T317-Y323 HydrophobicContact CG2-CE1 3.7Å; Y323-E326 HydrophobicContact CE2-CG 4.03Å; Y323-H328 WeakPolarHBondContact CB-O 3.09Å; Y323-H329 AromaticContact CD1-ND1 3.88Å; Y323-H329 AromaticContact CG-ND1 3.74Å
324L81.9Confident82.5Confident26 Ų2666 Ų6614%0.13635%0.349CS..SBendtrans-108.3-34.2170.8-79.9173.1000112.4V295 I314 L336 M347V295-L324 HydrophobicContact CG2-CD1 3.86Å; V295-L324 HydrophobicContact CG2-CD2 4.01Å; V295-L324 HydrophobicContact CG2-CG 4.48Å; I314-L324 HydrophobicContact CG1-CD2 3.84Å; I314-L324 HydrophobicContact CG1-CG 4.36Å; L324-L336 HydrophobicContact CD1-CD2 3.42Å; L324-L336 VanDerWaalsContact CD1-CD2 3.42Å; L324-L336 HydrophobicContact CD1-CG 4.32Å; L324-L336 HydrophobicContact CG-CD1 4.17Å; L324-L336 HydrophobicContact CG-CD2 3.82Å; L324-L336 HydrophobicContact CG-CG 4.35Å; L324-M347 HydrophobicContact CD1-SD 3.96Å
325A73.4Confident82.3Confident24 Ų2470.2 Ų70.220%0.19837%0.369CS..SBendtrans-120.2132.8172.800000108.2K327 H328 A345A325-K327 PolarHBondContact O-N 3.46Å; A325-H328 PolarHBondContact O-N 2.82Å; A325-H328 VanDerWaalsContact O-N 3.14Å; A325-A345 VanDerWaalsContact CB-O 3.29Å; A325-A345 WeakPolarHBondContact CB-O 3.33Å
326E65.4Low82.4Confident164 Ų16468.2 Ų68.277%0.76636%0.355SS*.THydrogen-bonded Turntrans-55.5-16-170.4-67.8179.6173.100114.9Y323 H329Y323-E326 HydrophobicContact CE2-CG 4.03Å; E326-H329 PolarHBondContact O-CE1 3.26Å; E326-H329 VanDerWaalsContact O-CE1 3.26Å
327K71Confident82.6Confident192 Ų19265.1 Ų65.184%0.83534%0.336SS*.THydrogen-bonded Turntrans-85.9-12.1-177.5-63.1-172.5178.9-176.60115.3A325A325-K327 PolarHBondContact O-N 3.46Å
328H79.2Confident82.4Confident75 Ų7568.6 Ų68.635%0.34736%0.355SS..  trans-135.6127.6-177.2-59.991.9000111.4Y323 A325 F330 Y339Y323-H328 WeakPolarHBondContact CB-O 3.09Å; A325-H328 PolarHBondContact O-N 2.82Å; A325-H328 VanDerWaalsContact O-N 3.14Å; H328-F330 HydrophobicContact CB-CE2 3.94Å; H328-F330 HydrophobicContact CB-CZ 3.84Å; H328-Y339 AromaticContact CD2-CZ 3.98Å; H328-Y339 PolarHBondContact CE1-OH 2.92Å; H328-Y339 PolarHBondContact NE2-OH 3.49Å
329H87.4Confident82.6Confident87 Ų8765.3 Ų65.340%0.40333%0.326SS..  trans-119.8139.9-178.3-55.7-31000110.4Q321 Y323 E326Q321-H329 HydrophobicContact CB-CB 4.06Å; Y323-H329 AromaticContact CD1-ND1 3.88Å; Y323-H329 AromaticContact CG-ND1 3.74Å; E326-H329 PolarHBondContact O-CE1 3.26Å; E326-H329 VanDerWaalsContact O-CE1 3.26Å
330F87.3Confident82.6Confident26 Ų2658.4 Ų58.411%0.11429%0.294CS..BIsolated β-bridgetrans-128.7151.2-174.1-54.8-81.1000110.8Q321 F322 H328 E335 L336 Y339Q321-F330 CarbonylContact C-O 3.49Å; Q321-F330 VanDerWaalsContact CA-O 3.29Å; Q321-F330 WeakPolarHBondContact CA-O 3.38Å; Q321-F330 WeakPolarHBondContact CB-O 3.49Å; F322-F330 PolarHBondContact N-O 3.05Å; F322-F330 WeakPolarHBondContact O-CD2 3.32Å; F322-F330 PolarHBondContact O-N 2.88Å; H328-F330 HydrophobicContact CB-CE2 3.94Å; H328-F330 HydrophobicContact CB-CZ 3.84Å; F330-E335 HydrophobicContact CB-CB 4.26Å; F330-E335 HydrophobicContact CD1-CB 4.35Å; F330-L336 HydrophobicContact CB-CB 3.93Å; F330-L336 HydrophobicContact CD2-CB 3.46Å; F330-L336 VanDerWaalsContact CD2-CB 3.46Å; F330-L336 HydrophobicContact CD2-CD1 3.94Å; F330-L336 HydrophobicContact CD2-CG 3.68Å; F330-L336 HydrophobicContact CE2-CB 4.12Å; F330-L336 HydrophobicContact CE2-CG 4.05Å; F330-L336 HydrophobicContact CG-CB 3.74Å; F330-L336 HydrophobicContact CG-CG 4.46Å; F330-Y339 HydrophobicContact CE1-CD1 4.25Å; F330-Y339 HydrophobicContact CE1-CD2 4.06Å; F330-Y339 AromaticContact CE1-CG 3.7Å; F330-Y339 HydrophobicContact CE1-CG 3.7Å; F330-Y339 HydrophobicContact CE2-CD1 4.35Å; F330-Y339 AromaticContact CZ-CD1 3.5Å; F330-Y339 HydrophobicContact CZ-CD1 3.5Å; F330-Y339 VanDerWaalsContact CZ-CD1 3.5Å; F330-Y339 HydrophobicContact CZ-CD2 4.07Å; F330-Y339 HydrophobicContact CZ-CE1 4.15Å; F330-Y339 AromaticContact CZ-CG 3.44Å; F330-Y339 HydrophobicContact CZ-CG 3.44Å; F330-Y339 VanDerWaalsContact CZ-CG 3.44Å
331N84.7Confident82.6Confident103 Ų10359 Ų5955%0.55129%0.285SS*.SBendtrans-83.9-23.8-178.2-63.5-34.6000111.9Q321 E335Q321-N331 PolarHBondContact NE2-OD1 3.44Å; N331-E335 PolarHBondContact N-OE2 2.66Å; N331-E335 VanDerWaalsContact N-OE2 3.15Å
332T84.4Confident81.9Confident58 Ų5862.1 Ų62.136%0.35630%0.299SS..SBendtrans-135.1153.9176.672.40000112.1E335 L336T332-E335 PolarHBondContact N-OE2 3.24Å; T332-E335 PolarHBondContact O-N 3.35Å; T332-E335 VanDerWaalsContact OG1-CG 3.32Å; T332-E335 WeakPolarHBondContact OG1-CG 3.4Å; T332-E335 PolarHBondContact OG1-N 3.22Å; T332-L336 PolarHBondContact O-N 3.39Å
333I85.4Confident81.4Confident7 Ų763.4 Ų63.44%0.03631%0.308CS..Hα-helixtrans-61.6-40.2175.6-68.4162.2000112.1L254 W259 Y293 I314 F322 E335 L336 I337L254-I333 HydrophobicContact CD1-CB 4.46Å; L254-I333 HydrophobicContact CD1-CD1 3.61Å; L254-I333 HydrophobicContact CD1-CG2 4.5Å; L254-I333 HydrophobicContact CD2-CB 4.04Å; L254-I333 HydrophobicContact CD2-CG2 4.33Å; W259-I333 HydrophobicContact CH2-CG2 3.81Å; W259-I333 HydrophobicContact CZ3-CG2 4.08Å; Y293-I333 HydrophobicContact CD2-CD1 3.25Å; Y293-I333 HydrophobicContact CE2-CD1 3.42Å; Y293-I333 VanDerWaalsContact CE2-CD1 3.42Å; Y293-I333 HydrophobicContact CG-CD1 3.96Å; I314-I333 HydrophobicContact CD1-CG1 4.36Å; I314-I333 HydrophobicContact CD1-CG2 3.9Å; I314-I333 HydrophobicContact CG2-CG1 4.43Å; F322-I333 HydrophobicContact CB-CG1 4.41Å; F322-I333 HydrophobicContact CD1-CD1 4.11Å; F322-I333 HydrophobicContact CD1-CG1 3.84Å; F322-I333 HydrophobicContact CD2-CG1 4.11Å; F322-I333 HydrophobicContact CE1-CD1 3.94Å; F322-I333 HydrophobicContact CE1-CG1 4.09Å; F322-I333 HydrophobicContact CE2-CG1 4.36Å; F322-I333 HydrophobicContact CG-CG1 3.84Å; F322-I333 HydrophobicContact CZ-CD1 4.26Å; F322-I333 HydrophobicContact CZ-CG1 4.34Å; I333-E335 VanDerWaalsContact C-N 3.34Å; I333-E335 PolarHBondContact O-N 2.95Å; I333-L336 WeakPolarHBondContact O-CB 3.45Å; I333-L336 PolarHBondContact O-N 3.12Å; I333-I337 HydrophobicContact CG2-CG1 4.19Å; I333-I337 WeakPolarHBondContact O-CG1 3.1Å; I333-I337 PolarHBondContact O-N 3.3Å
334P86.6Confident80.7Confident29 Ų2962.8 Ų62.819%0.18831%0.314CS..Hα-helixtrans-58.3-39.7174.3-27.937.3000114.2L254 F257 W259 L336 I337 N338L254-P334 HydrophobicContact CD2-CG 4.16Å; F257-P334 HydrophobicContact CD2-CG 4.09Å; F257-P334 HydrophobicContact CE1-CB 4.13Å; F257-P334 HydrophobicContact CE1-CG 4.15Å; F257-P334 HydrophobicContact CE2-CB 4.13Å; F257-P334 HydrophobicContact CE2-CG 3.27Å; F257-P334 HydrophobicContact CZ-CB 3.68Å; F257-P334 HydrophobicContact CZ-CG 3.29Å; W259-P334 HydrophobicContact CH2-CG 4.27Å; W259-P334 HydrophobicContact CZ2-CB 4.25Å; W259-P334 HydrophobicContact CZ2-CG 4.13Å; P334-L336 VanDerWaalsContact C-N 3.35Å; P334-I337 PolarHBondContact O-N 3.32Å; P334-N338 WeakPolarHBondContact O-CB 3.28Å; P334-N338 PolarHBondContact O-N 3.34Å
335E84.3Confident80.4Confident90 Ų9063.2 Ų63.242%0.42132%0.321SS..Hα-helixtrans-62.3-43.2174.8-75.1167-172.200111.8F330 N331 T332 I333 N338 Y339F330-E335 HydrophobicContact CB-CB 4.26Å; F330-E335 HydrophobicContact CD1-CB 4.35Å; N331-E335 PolarHBondContact N-OE2 2.66Å; N331-E335 VanDerWaalsContact N-OE2 3.15Å; T332-E335 PolarHBondContact N-OE2 3.24Å; T332-E335 PolarHBondContact O-N 3.35Å; T332-E335 VanDerWaalsContact OG1-CG 3.32Å; T332-E335 WeakPolarHBondContact OG1-CG 3.4Å; T332-E335 PolarHBondContact OG1-N 3.22Å; I333-E335 VanDerWaalsContact C-N 3.34Å; I333-E335 PolarHBondContact O-N 2.95Å; E335-N338 PolarHBondContact O-N 2.99Å; E335-Y339 PolarHBondContact O-N 3.03Å
336L88.3Confident80.2Confident0 Ų065.7 Ų65.70%035%0.349CS..Hα-helixtrans-60.6-46.4175.8175162.1000111.3I314 F322 L324 F330 T332 I333 P334 Y339 H340I314-L336 HydrophobicContact CD1-CD2 4.47Å; I314-L336 HydrophobicContact CG2-CD1 3.95Å; F322-L336 HydrophobicContact CB-CD1 3.85Å; L324-L336 HydrophobicContact CD1-CD2 3.42Å; L324-L336 VanDerWaalsContact CD1-CD2 3.42Å; L324-L336 HydrophobicContact CD1-CG 4.32Å; L324-L336 HydrophobicContact CG-CD1 4.17Å; L324-L336 HydrophobicContact CG-CD2 3.82Å; L324-L336 HydrophobicContact CG-CG 4.35Å; F330-L336 HydrophobicContact CB-CB 3.93Å; F330-L336 HydrophobicContact CD2-CB 3.46Å; F330-L336 VanDerWaalsContact CD2-CB 3.46Å; F330-L336 HydrophobicContact CD2-CD1 3.94Å; F330-L336 HydrophobicContact CD2-CG 3.68Å; F330-L336 HydrophobicContact CE2-CB 4.12Å; F330-L336 HydrophobicContact CE2-CG 4.05Å; F330-L336 HydrophobicContact CG-CB 3.74Å; F330-L336 HydrophobicContact CG-CG 4.46Å; T332-L336 PolarHBondContact O-N 3.39Å; I333-L336 WeakPolarHBondContact O-CB 3.45Å; I333-L336 PolarHBondContact O-N 3.12Å; P334-L336 VanDerWaalsContact C-N 3.35Å; L336-Y339 PolarHBondContact O-N 2.68Å; L336-H340 PolarHBondContact O-CD2 3.4Å; L336-H340 VanDerWaalsContact O-CD2 3.25Å; L336-H340 PolarHBondContact O-N 3.16Å; L336-H340 VanDerWaalsContact O-N 3.07Å
337I88.1Confident80.9Confident2 Ų258.7 Ų58.71%0.0132%0.316CS..Hα-helixtrans-64.2-46178.1-63.6-57.3000110.7W259 F282 I284 V295 I333 P334 Y339 H340 Q341 L351W259-I337 HydrophobicContact CH2-CG1 4.15Å; W259-I337 HydrophobicContact CZ2-CB 4.43Å; W259-I337 HydrophobicContact CZ2-CG1 4.22Å; W259-I337 HydrophobicContact CZ3-CG1 4.33Å; F282-I337 HydrophobicContact CE2-CG2 3.75Å; F282-I337 HydrophobicContact CZ-CG2 4.07Å; I284-I337 HydrophobicContact CD1-CD1 3.55Å; I284-I337 HydrophobicContact CD1-CG1 4Å; I284-I337 HydrophobicContact CG1-CD1 3.74Å; I284-I337 HydrophobicContact CG1-CG1 4.33Å; V295-I337 HydrophobicContact CG2-CD1 3.95Å; I333-I337 HydrophobicContact CG2-CG1 4.19Å; I333-I337 WeakPolarHBondContact O-CG1 3.1Å; I333-I337 PolarHBondContact O-N 3.3Å; P334-I337 PolarHBondContact O-N 3.32Å; I337-Y339 VanDerWaalsContact C-N 3.31Å; I337-Y339 PolarHBondContact O-N 2.95Å; I337-H340 CarbonylContact O-C 3.5Å; I337-H340 PolarHBondContact O-N 3.13Å; I337-H340 VanDerWaalsContact O-N 3.12Å; I337-Q341 HydrophobicContact CG2-CG 4.38Å; I337-Q341 WeakPolarHBondContact O-CG 3Å; I337-Q341 PolarHBondContact O-N 3.48Å; I337-L351 HydrophobicContact CD1-CD1 4Å; I337-L351 HydrophobicContact CG2-CD1 4.13Å
338N81.4Confident81.3Confident89 Ų8952.8 Ų52.848%0.47630%0.297SS..Hα-helixtrans-58.7-42177.7-177.751.6000112.1P334 E335 Q341 H342P334-N338 WeakPolarHBondContact O-CB 3.28Å; P334-N338 PolarHBondContact O-N 3.34Å; E335-N338 PolarHBondContact O-N 2.99Å; N338-Q341 PolarHBondContact O-N 3.24Å; N338-H342 PolarHBondContact O-ND1 2.86Å
339Y83.6Confident81.3Confident60 Ų6049.9 Ų49.924%0.23528%0.284CS..Hα-helixtrans-61.3-45.7174.8178-91.5000112H328 F330 E335 L336 I337 Q341 H342 N343 A345H328-Y339 AromaticContact CD2-CZ 3.98Å; H328-Y339 PolarHBondContact CE1-OH 2.92Å; H328-Y339 PolarHBondContact NE2-OH 3.49Å; F330-Y339 HydrophobicContact CE1-CD1 4.25Å; F330-Y339 HydrophobicContact CE1-CD2 4.06Å; F330-Y339 AromaticContact CE1-CG 3.7Å; F330-Y339 HydrophobicContact CE1-CG 3.7Å; F330-Y339 HydrophobicContact CE2-CD1 4.35Å; F330-Y339 AromaticContact CZ-CD1 3.5Å; F330-Y339 HydrophobicContact CZ-CD1 3.5Å; F330-Y339 VanDerWaalsContact CZ-CD1 3.5Å; F330-Y339 HydrophobicContact CZ-CD2 4.07Å; F330-Y339 HydrophobicContact CZ-CE1 4.15Å; F330-Y339 AromaticContact CZ-CG 3.44Å; F330-Y339 HydrophobicContact CZ-CG 3.44Å; F330-Y339 VanDerWaalsContact CZ-CG 3.44Å; E335-Y339 PolarHBondContact O-N 3.03Å; L336-Y339 PolarHBondContact O-N 2.68Å; I337-Y339 VanDerWaalsContact C-N 3.31Å; I337-Y339 PolarHBondContact O-N 2.95Å; Y339-Q341 VanDerWaalsContact C-N 3.31Å; Y339-Q341 PolarHBondContact O-N 3.1Å; Y339-H342 PolarHBondContact O-N 3.46Å; Y339-N343 HydrophobicContact CD1-CB 4.4Å; Y339-N343 HydrophobicContact CE1-CB 3.94Å; Y339-N343 PolarHBondContact O-N 2.79Å; Y339-N343 PolarHBondContact O-ND2 2.87Å; Y339-N343 VanDerWaalsContact O-ND2 3.16Å; Y339-A345 HydrophobicContact CE1-CB 3.66Å
340H81.9Confident81.1Confident2 Ų251.9 Ų51.91%0.00929%0.288CS..Hα-helixtrans-76.7-13.6-178.3-77.2-73000114.6L336 I337 H342 N343 M347 L351L336-H340 PolarHBondContact O-CD2 3.4Å; L336-H340 VanDerWaalsContact O-CD2 3.25Å; L336-H340 PolarHBondContact O-N 3.16Å; L336-H340 VanDerWaalsContact O-N 3.07Å; I337-H340 CarbonylContact O-C 3.5Å; I337-H340 PolarHBondContact O-N 3.13Å; I337-H340 VanDerWaalsContact O-N 3.12Å; H340-H342 VanDerWaalsContact C-N 3.32Å; H340-N343 CarbonylContact C-O 3.6Å; H340-N343 VanDerWaalsContact CA-O 3.27Å; H340-N343 WeakPolarHBondContact CA-O 3.48Å; H340-N343 PolarHBondContact ND1-O 3.05Å; H340-M347 HydrophobicContact CB-SD 4.21Å; H340-M347 PolarHBondContact ND1-SD 2.95Å; H340-L351 HydrophobicContact CB-CD1 3.73Å; H340-L351 HydrophobicContact CB-CG 4.02Å; H340-L351 PolarHBondContact O-N 3.35Å
341Q79.8Confident81Confident54 Ų5450.8 Ų50.825%0.25228%0.284SS..Hα-helixtrans-68.3-34.7165.9-75.8176-3700112.1F282 I337 N338 Y339 L351F282-Q341 HydrophobicContact CE1-CG 4.46Å; F282-Q341 HydrophobicContact CZ-CG 4.24Å; I337-Q341 HydrophobicContact CG2-CG 4.38Å; I337-Q341 WeakPolarHBondContact O-CG 3Å; I337-Q341 PolarHBondContact O-N 3.48Å; N338-Q341 PolarHBondContact O-N 3.24Å; Y339-Q341 VanDerWaalsContact C-N 3.31Å; Y339-Q341 PolarHBondContact O-N 3.1Å; Q341-L351 VanDerWaalsContact CA-O 3.23Å; Q341-L351 WeakPolarHBondContact CA-O 3.44Å; Q341-L351 HydrophobicContact CB-CB 4.46Å; Q341-L351 HydrophobicContact CG-CB 3.8Å
342H74.1Confident80.7Confident122 Ų12249.9 Ų49.957%0.56528%0.275SS*.Hα-helixtrans-92.1-31.1-179.2-63.983.4000112.4N338 Y339 H340N338-H342 PolarHBondContact O-ND1 2.86Å; Y339-H342 PolarHBondContact O-N 3.46Å; H340-H342 VanDerWaalsContact C-N 3.32Å
343N75.8Confident80.4Confident71 Ų7151.3 Ų51.338%0.3828%0.278SS..  trans-129.6129.3-172.5-55-78.9000112Y339 H340 A345Y339-N343 HydrophobicContact CD1-CB 4.4Å; Y339-N343 HydrophobicContact CE1-CB 3.94Å; Y339-N343 PolarHBondContact O-N 2.79Å; Y339-N343 PolarHBondContact O-ND2 2.87Å; Y339-N343 VanDerWaalsContact O-ND2 3.16Å; H340-N343 CarbonylContact C-O 3.6Å; H340-N343 VanDerWaalsContact CA-O 3.27Å; H340-N343 WeakPolarHBondContact CA-O 3.48Å; H340-N343 PolarHBondContact ND1-O 3.05Å; N343-A345 HydrophobicContact CB-CB 4.39Å
344A71.6Confident80.1Confident37 Ų3754.7 Ų54.731%0.30630%0.295SS..  trans-68.7-37.217500000112.2G346 M347 R350A344-G346 PolarHBondContact O-N 2.71Å; A344-M347 VanDerWaalsContact O-CB 3.3Å; A344-M347 WeakPolarHBondContact O-CB 3.22Å; A344-M347 WeakPolarHBondContact O-CG 3.39Å; A344-M347 PolarHBondContact O-N 2.71Å; A344-R350 HydrophobicContact CB-CB 4.42Å
345A74.6Confident79.8Confident35 Ų3553.4 Ų53.429%0.28929%0.287SS..THydrogen-bonded Turntrans44.440.1171.500000115.7A325 Y339 N343A325-A345 VanDerWaalsContact CB-O 3.29Å; A325-A345 WeakPolarHBondContact CB-O 3.33Å; Y339-A345 HydrophobicContact CE1-CB 3.66Å; N343-A345 HydrophobicContact CB-CB 4.39Å
346G70.2Confident79.1Confident77 Ų7750.9 Ų50.979%0.79428%0.279SS*.THydrogen-bonded Turntrans102.2-6.4-179.500000115.4A344A344-G346 PolarHBondContact O-N 2.71Å
347M79.9Confident78Confident16 Ų1655.5 Ų55.58%0.07930%0.303CS..SBendtrans-81.8159.5170.7-60.9178.662.100111.6V295 L297 Y312 L324 H340 A344 S349 L351V295-M347 HydrophobicContact CG1-CE 4.4Å; L297-M347 HydrophobicContact CD2-CE 3.78Å; Y312-M347 HydrophobicContact CD1-CG 4.44Å; Y312-M347 HydrophobicContact CD2-CE 3.66Å; Y312-M347 HydrophobicContact CE1-CB 4.47Å; Y312-M347 HydrophobicContact CE1-CG 4.22Å; Y312-M347 HydrophobicContact CE2-CE 3.76Å; Y312-M347 HydrophobicContact CG-CE 4.21Å; L324-M347 HydrophobicContact CD1-SD 3.96Å; H340-M347 HydrophobicContact CB-SD 4.21Å; H340-M347 PolarHBondContact ND1-SD 2.95Å; A344-M347 VanDerWaalsContact O-CB 3.3Å; A344-M347 WeakPolarHBondContact O-CB 3.22Å; A344-M347 WeakPolarHBondContact O-CG 3.39Å; A344-M347 PolarHBondContact O-N 2.71Å; M347-S349 PolarHBondContact O-N 3.15Å; M347-L351 HydrophobicContact CE-CD2 3.76Å
348V78.1Confident76.5Confident69 Ų6959.2 Ų59.242%0.41832%0.317SS..SBendtrans-64.6-26.1-178.371.20000113L297 T299 R310 Y312L297-V348 HydrophobicContact CD2-CG1 3.72Å; L297-V348 HydrophobicContact CG-CG1 4.35Å; T299-V348 HydrophobicContact CG2-CB 4.44Å; T299-V348 HydrophobicContact CG2-CG1 3.82Å; T299-V348 HydrophobicContact CG2-CG2 3.73Å; R310-V348 HydrophobicContact CB-CG1 4.27Å; R310-V348 HydrophobicContact CG-CB 4.46Å; R310-V348 HydrophobicContact CG-CG1 3.89Å; Y312-V348 WeakPolarHBondContact OH-CB 3.38Å; Y312-V348 WeakPolarHBondContact OH-CG1 3.34Å; Y312-V348 PolarHBondContact OH-N 2.77Å
349S80.7Confident74.9Confident13 Ų1358 Ų589%0.09132%0.32CS..SBendtrans-154.1157.9170.3172.50000108.4L297 M347 K352L297-S349 WeakPolarHBondContact CD2-O 3.23Å; M347-S349 PolarHBondContact O-N 3.15Å; S349-K352 WeakPolarHBondContact OG-CE 3.22Å
350R82.6Confident72.7Confident129 Ų12964.4 Ų64.449%0.48734%0.344SS..  trans-63.8157162.572.1-178.2-175.8-177.9-0.4110.6A344 K352A344-R350 HydrophobicContact CB-CB 4.42Å; R350-K352 HydrophobicContact CG-CG 3.81Å; R350-K352 PolarHBondContact O-N 2.85Å
351L85Confident70.5Confident3 Ų367.8 Ų67.82%0.01637%0.366CS..  trans-76.9109.9177.3-54.4180000109.3F282 V295 L297 I337 H340 Q341 M347F282-L351 HydrophobicContact CB-CD2 3.68Å; F282-L351 HydrophobicContact CD1-CB 3.6Å; F282-L351 HydrophobicContact CD1-CD2 4.29Å; F282-L351 HydrophobicContact CD1-CG 4.41Å; F282-L351 HydrophobicContact CD2-CB 4.19Å; F282-L351 HydrophobicContact CD2-CD1 3.91Å; F282-L351 HydrophobicContact CD2-CD2 4.01Å; F282-L351 HydrophobicContact CD2-CG 4.26Å; F282-L351 HydrophobicContact CE1-CB 3.7Å; F282-L351 HydrophobicContact CE2-CB 4.29Å; F282-L351 HydrophobicContact CE2-CD1 3.97Å; F282-L351 HydrophobicContact CG-CB 3.86Å; F282-L351 HydrophobicContact CG-CD1 4.33Å; F282-L351 HydrophobicContact CG-CD2 3.73Å; F282-L351 HydrophobicContact CG-CG 4.17Å; F282-L351 HydrophobicContact CZ-CB 4.06Å; F282-L351 HydrophobicContact CZ-CD1 4.44Å; V295-L351 HydrophobicContact CG1-CD2 4.03Å; L297-L351 HydrophobicContact CD1-CD2 4.01Å; L297-L351 HydrophobicContact CD2-CD2 4.38Å; I337-L351 HydrophobicContact CD1-CD1 4Å; I337-L351 HydrophobicContact CG2-CD1 4.13Å; H340-L351 HydrophobicContact CB-CD1 3.73Å; H340-L351 HydrophobicContact CB-CG 4.02Å; H340-L351 PolarHBondContact O-N 3.35Å; Q341-L351 VanDerWaalsContact CA-O 3.23Å; Q341-L351 WeakPolarHBondContact CA-O 3.44Å; Q341-L351 HydrophobicContact CB-CB 4.46Å; Q341-L351 HydrophobicContact CG-CB 3.8Å; M347-L351 HydrophobicContact CE-CD2 3.76Å
352K77.6Confident68.7Low85 Ų8568.5 Ų68.537%0.3738%0.375SS..  trans-106.5-46.3-171.2-61.9178.2-167.9168.10113D279 G280 S349 R350D279-K352 IonicContact OD2-NZ 2.77Å; D279-K352 PolarHBondContact OD2-NZ 2.91Å; G280-K352 PolarHBondContact O-N 3.37Å; S349-K352 WeakPolarHBondContact OG-CE 3.22Å; R350-K352 HydrophobicContact CG-CG 3.81Å; R350-K352 PolarHBondContact O-N 2.85Å
353H78.5Confident67.2Low88 Ų8864.5 Ų64.541%0.40736%0.361SS..EExtended strand (participates in β ladder)trans-127.1123.6-170.7-58-68.2000110.5K278 D279 G280 G281 F282K278-H353 HydrophobicContact CB-CB 4.25Å; K278-H353 HydrophobicContact CD-CB 4.18Å; D279-H353 PolarHBondContact O-CD2 3.3Å; D279-H353 VanDerWaalsContact O-CD2 3.29Å; G280-H353 PolarHBondContact O-N 3.04Å; G281-H353 CarbonylContact C-O 3.46Å; G281-H353 VanDerWaalsContact CA-O 3.26Å; G281-H353 WeakPolarHBondContact CA-O 3.28Å; F282-H353 WeakPolarHBondContact CD1-O 3.27Å; F282-H353 PolarHBondContact N-O 3.39Å
354I79.8Confident65.8Low77 Ų7762.1 Ų62.140%0.39535%0.349SS..EExtended strand (participates in β ladder)trans-70.3132174.6-62.7170.6000108.4D258 W259 F282D258-I354 HydrophobicContact CB-CG2 4.19Å; W259-I354 HydrophobicContact CB-CG1 4.34Å; W259-I354 HydrophobicContact CB-CG2 3.88Å; F282-I354 HydrophobicContact CE1-CG1 3.84Å; F282-I354 HydrophobicContact CZ-CG1 3.77Å
355V79.7Confident64.4Low3 Ų360.5 Ų60.52%0.01834%0.336CS..  trans-116.9122.2171.4173.30000107.3L272 L273 E276 F282 L283L272-V355 HydrophobicContact CD1-CG1 4.47Å; L272-V355 HydrophobicContact CD2-CG1 3.91Å; L272-V355 HydrophobicContact CG-CG1 3.6Å; L273-V355 HydrophobicContact CD2-CB 3.87Å; L273-V355 HydrophobicContact CD2-CG1 4.14Å; L273-V355 HydrophobicContact CD2-CG2 3.84Å; E276-V355 HydrophobicContact CB-CG1 4.49Å; E276-V355 HydrophobicContact CB-CG2 4.03Å; E276-V355 HydrophobicContact CG-CG1 3.94Å; E276-V355 HydrophobicContact CG-CG2 4.07Å; F282-V355 PolarHBondContact O-N 2.89Å; L283-V355 VanDerWaalsContact CB-O 3.3Å; L283-V355 WeakPolarHBondContact CB-O 3.3Å; L283-V355 HydrophobicContact CD2-CG1 4.27Å
356S70.6Confident63.4Low36 Ų3659.1 Ų59.125%0.25232%0.324SS..  trans-125.8153.1-174-166.80000110.6D258 R358D258-S356 WeakPolarHBondContact O-CB 3.39Å; D258-S356 PolarHBondContact O-OG 2.84Å; S356-R358 VanDerWaalsContact C-N 3.32Å; S356-R358 WeakPolarHBondContact OG-CG 3.31Å; S356-R358 PolarHBondContact OG-N 3.06Å
357N63.7Low62.6Low98 Ų9855.8 Ų55.852%0.52429%0.288SS..  trans-90.53.3170.376.6-25.1000112.8M264 L272 A359M264-N357 HydrophobicContact CE-CB 3.69Å; L272-N357 HydrophobicContact CD2-CB 4.31Å; N357-A359 PolarHBondContact O-N 2.57Å
358R58.3Low61.2Low79 Ų7955.2 Ų55.230%0.29829%0.286SS..PPolyproline II helixtrans-68.5118.5177-68.8-179.9173.1-173.5-14.4109.1E251 E255 D258 S356E251-R358 IonicContact OE1-NH2 3.57Å; E251-R358 IonicContact OE2-NH2 2.73Å; E251-R358 PolarHBondContact OE2-NH2 3.39Å; E255-R358 PolarHBondContact O-NH2 3.11Å; D258-R358 IonicContact OD1-CZ 2.69Å; D258-R358 IonicContact OD1-NH1 2.96Å; D258-R358 PolarHBondContact OD1-NH1 2.81Å; S356-R358 VanDerWaalsContact C-N 3.32Å; S356-R358 WeakPolarHBondContact OG-CG 3.31Å; S356-R358 PolarHBondContact OG-N 3.06Å
359A46Very low59.5Low65 Ų6555.5 Ų55.554%0.53728%0.28SS..PPolyproline II helixtrans-60.6151.7177.200000110.8Y201 N357Y201-A359 PolarHBondContact OH-O 2.97Å; N357-A359 PolarHBondContact O-N 2.57Å
360R37.8Very low58Low194 Ų19458.1 Ų58.173%0.73231%0.309SS*.PPolyproline II helixtrans-60.4154.8166.4-76.7-178.3-175.9166.95.7109.6N510R360-N510 PolarHBondContact NH1-OD1 2.98Å
361P36.4Very low56.9Low72 Ų7254.8 Ų54.847%0.46830%0.303SS..PPolyproline II helixtrans-54.3128.2-171.617.9-30.4000111.3Y201Y201-P361 HydrophobicContact CD1-CB 3.75Å; Y201-P361 HydrophobicContact CD1-CG 4.08Å; Y201-P361 HydrophobicContact CD2-CB 4.33Å; Y201-P361 HydrophobicContact CE1-CB 3.67Å; Y201-P361 HydrophobicContact CE1-CG 4.05Å; Y201-P361 HydrophobicContact CE2-CB 4.3Å; Y201-P361 HydrophobicContact CG-CB 4.09Å
362P41Very low56.2Low70 Ų7057.9 Ų57.946%0.45531%0.314SS..PPolyproline II helixtrans-64.9146.9168.724.8-29.8000109.9T364P362-T364 PolarHBondContact O-N 3.33Å
363S42.9Very low56.2Low37 Ų3755.9 Ų55.926%0.25931%0.307SS..  trans-41.6132.6171.9-70.30000111.3
364T47.4Very low56.3Low22 Ų2252 Ų5214%0.13529%0.289CS..  trans-51.7147.9-179.346.80000112M206 Y246 P362 G366M206-T364 HydrophobicContact CE-CG2 4.07Å; Y246-T364 HydrophobicContact CE2-CG2 3.9Å; Y246-T364 WeakPolarHBondContact OH-CG2 3.06Å; P362-T364 PolarHBondContact O-N 3.33Å; T364-G366 PolarHBondContact O-N 3.1Å
365A42.2Very low56.3Low3 Ų350.7 Ų50.73%0.02528%0.283CS..SBendtrans-65.349.8173.200000114N228 W229 R430N228-A365 HydrophobicContact CB-CB 4.33Å; W229-A365 PolarHBondContact NE1-O 3.15Å; A365-R430 VanDerWaalsContact CA-CZ 3.5Å; A365-R430 VanDerWaalsContact CA-NH2 3.29Å; A365-R430 PolarHBondContact O-NH2 2.97Å; A365-R430 VanDerWaalsContact O-NH2 3.07Å
366G52.5Low56.5Low5 Ų551.3 Ų51.35%0.05229%0.286CS..SBendtrans76.7-167.8-174.600000114T364 G368T364-G366 PolarHBondContact O-N 3.1Å; G366-G368 VanDerWaalsContact C-N 3.31Å; G366-G368 PolarHBondContact O-N 3.15Å
367L53.7Low57.2Low8 Ų859.4 Ų59.44%0.04231%0.311CS..SBendtrans-87.219.9-161-44.8156.2000114.4V371 I374 W398 Y438L367-V371 HydrophobicContact CB-CB 4.16Å; L367-V371 HydrophobicContact CB-CG1 4.04Å; L367-V371 HydrophobicContact CD1-CG1 4.02Å; L367-I374 HydrophobicContact CD1-CB 4.5Å; L367-I374 HydrophobicContact CD1-CD1 3.89Å; L367-I374 HydrophobicContact CD1-CG1 3.21Å; L367-I374 HydrophobicContact CD2-CD1 3.81Å; L367-I374 HydrophobicContact CD2-CG1 3.81Å; L367-I374 HydrophobicContact CG-CD1 4.48Å; L367-I374 HydrophobicContact CG-CG1 4.16Å; L367-W398 HydrophobicContact CB-CH2 3.67Å; L367-W398 HydrophobicContact CB-CZ2 3.94Å; L367-W398 HydrophobicContact CD2-CD2 3.95Å; L367-W398 HydrophobicContact CD2-CE3 3.79Å; L367-W398 HydrophobicContact CD2-CH2 3.14Å; L367-W398 HydrophobicContact CD2-CZ2 3.28Å; L367-W398 HydrophobicContact CD2-CZ3 3.39Å; L367-W398 HydrophobicContact CG-CH2 3.97Å; L367-W398 HydrophobicContact CG-CZ2 4.12Å; L367-Y438 WeakPolarHBondContact CG-O 3.36Å
368G50.2Low58.2Low3 Ų357.7 Ų57.73%0.03130%0.303CS..SBendtrans111.2159.5-16100000112.5W229 G366 G370 V371W229-G368 VanDerWaalsContact CH2-CA 3.47Å; W229-G368 VanDerWaalsContact CZ2-C 3.46Å; G366-G368 VanDerWaalsContact C-N 3.31Å; G366-G368 PolarHBondContact O-N 3.15Å; G368-G370 PolarHBondContact O-N 2.67Å; G368-V371 PolarHBondContact O-N 3.04Å
369Y42.8Very low59.7Low76 Ų7654.5 Ų54.530%0.29829%0.291SS..THydrogen-bonded Turntrans-58.2123.9179.1179-117.3000111.6D226 W229 Y241 V371D226-Y369 HydrophobicContact CB-CD2 4.32Å; D226-Y369 HydrophobicContact CB-CE2 3.56Å; D226-Y369 WeakPolarHBondContact OD2-CE2 3.48Å; W229-Y369 HydrophobicContact CB-CD2 3.48Å; W229-Y369 VanDerWaalsContact CB-CD2 3.48Å; W229-Y369 HydrophobicContact CB-CE2 4.32Å; W229-Y369 HydrophobicContact CB-CG 4Å; W229-Y369 AromaticContact CD1-CD2 3.92Å; W229-Y369 AromaticContact CG-CD2 3.77Å; W229-Y369 HydrophobicContact CG-CD2 3.77Å; W229-Y369 HydrophobicContact CG-CG 4.17Å; Y241-Y369 HydrophobicContact CD1-CD1 4.27Å; Y241-Y369 HydrophobicContact CD1-CG 4.33Å; Y241-Y369 HydrophobicContact CD2-CD1 4.39Å; Y241-Y369 HydrophobicContact CE1-CD1 4.14Å; Y241-Y369 HydrophobicContact CE1-CE1 4.2Å; Y241-Y369 HydrophobicContact CE2-CD1 4.26Å; Y241-Y369 HydrophobicContact CG-CD1 4.39Å; Y241-Y369 HydrophobicContact CG-CG 4.45Å; Y369-V371 VanDerWaalsContact C-N 3.27Å; Y369-V371 PolarHBondContact O-N 2.64Å
370G49.8Very low61.9Low67 Ų6754.9 Ų54.969%0.69129%0.287SS*.THydrogen-bonded Turntrans760.1174.500000116.4G368G368-G370 PolarHBondContact O-N 2.67Å
371V59.5Low64.5Low60 Ų6049.3 Ų49.336%0.36427%0.268SS..  trans-94.4109.1179.6-1730000109.8T207 L367 G368 Y369T207-V371 HydrophobicContact CG2-CG2 4.35Å; L367-V371 HydrophobicContact CB-CB 4.16Å; L367-V371 HydrophobicContact CB-CG1 4.04Å; L367-V371 HydrophobicContact CD1-CG1 4.02Å; G368-V371 PolarHBondContact O-N 3.04Å; Y369-V371 VanDerWaalsContact C-N 3.27Å; Y369-V371 PolarHBondContact O-N 2.64Å
372W70.1Confident67.1Low67 Ų6750.1 Ų50.125%0.25427%0.268SS..  trans-112.4-18.1177.960.8-86.8000113.3I420 K424 M427 G439 V440W372-I420 HydrophobicContact CH2-CG1 4.46Å; W372-I420 HydrophobicContact CH2-CG2 3.75Å; W372-I420 HydrophobicContact CZ2-CG2 4.49Å; W372-I420 HydrophobicContact CZ3-CG1 4.37Å; W372-I420 HydrophobicContact CZ3-CG2 3.92Å; W372-K424 HydrophobicContact CD2-CG 4.5Å; W372-M427 HydrophobicContact CB-CE 3.65Å; W372-M427 HydrophobicContact CB-SD 3.39Å; W372-M427 WeakPolarHBondContact CB-SD 3.44Å; W372-G439 WeakPolarHBondContact O-CA 3.19Å; W372-V440 HydrophobicContact CE3-CG2 3.66Å; W372-V440 HydrophobicContact CZ3-CG2 3.75Å; W372-V440 PolarHBondContact O-N 3.49Å
373E76.4Confident69.6Low44 Ų4453.3 Ų53.321%0.20627%0.274CS..BIsolated β-bridgetrans-104.3120.6-176.7-166.1174.2-156.900110V440 T442 K443E373-V440 CarbonylContact C-O 3.53Å; E373-V440 VanDerWaalsContact CA-O 3.28Å; E373-V440 WeakPolarHBondContact CA-O 3.23Å; E373-T442 PolarHBondContact OE1-OG1 3.36Å; E373-K443 VanDerWaalsContact CD-CE 3.42Å; E373-K443 WeakPolarHBondContact OE1-CD 3.29Å; E373-K443 WeakPolarHBondContact OE1-CE 3.45Å; E373-K443 VanDerWaalsContact OE1-CG 3.24Å; E373-K443 WeakPolarHBondContact OE1-CG 3.27Å; E373-K443 PolarHBondContact OE1-N 2.91Å; E373-K443 IonicContact OE1-NZ 3.75Å; E373-K443 WeakPolarHBondContact OE2-CE 3.47Å; E373-K443 IonicContact OE2-NZ 2.68Å; E373-K443 PolarHBondContact OE2-NZ 3.33Å
374I81Confident72Confident5 Ų556.6 Ų56.63%0.02629%0.286CS..  trans-92.3133.3179-63.4165.8000108.6L367 P376 L379 V440 C441 V450L367-I374 HydrophobicContact CD1-CB 4.5Å; L367-I374 HydrophobicContact CD1-CD1 3.89Å; L367-I374 HydrophobicContact CD1-CG1 3.21Å; L367-I374 HydrophobicContact CD2-CD1 3.81Å; L367-I374 HydrophobicContact CD2-CG1 3.81Å; L367-I374 HydrophobicContact CG-CD1 4.48Å; L367-I374 HydrophobicContact CG-CG1 4.16Å; I374-P376 WeakPolarHBondContact O-CD 3.31Å; I374-L379 HydrophobicContact CG2-CD1 4.13Å; I374-L379 HydrophobicContact CG2-CD2 4.14Å; I374-L379 HydrophobicContact CG2-CG 3.94Å; I374-V440 PolarHBondContact N-O 3.04Å; I374-C441 PolarHBondContact O-SG 3.44Å; I374-V450 HydrophobicContact CD1-CB 3.49Å; I374-V450 VanDerWaalsContact CD1-CB 3.49Å; I374-V450 HydrophobicContact CD1-CG1 3.91Å; I374-V450 HydrophobicContact CD1-CG2 3.52Å
375D81.1Confident73.9Confident51 Ų5159.4 Ų59.427%0.27330%0.299SS..  trans-70.5123.1168.8-164.4-49.4000109.3R377 D378D375-R377 PolarHBondContact O-N 2.72Å; D375-R377 VanDerWaalsContact OD1-CB 3.26Å; D375-R377 WeakPolarHBondContact OD1-CB 3.35Å; D375-R377 VanDerWaalsContact OD1-CG 3.27Å; D375-R377 WeakPolarHBondContact OD1-CG 3.49Å; D375-R377 IonicContact OD1-CZ 3.7Å; D375-R377 PolarHBondContact OD1-N 3.44Å; D375-R377 IonicContact OD1-NE 3.7Å; D375-R377 PolarHBondContact OD1-NE 2.76Å; D375-R377 IonicContact OD1-NH2 3.15Å; D375-R377 IonicContact OD2-CZ 3.37Å; D375-R377 VanDerWaalsContact OD2-CZ 3.29Å; D375-R377 IonicContact OD2-NE 2.82Å; D375-R377 PolarHBondContact OD2-NE 2.91Å; D375-R377 VanDerWaalsContact OD2-NE 3.13Å; D375-R377 IonicContact OD2-NH2 3Å; D375-R377 PolarHBondContact OD2-NH2 2.76Å; D375-D378 WeakPolarHBondContact O-CB 3.49Å; D375-D378 PolarHBondContact O-N 2.69Å
376P83.9Confident75.8Confident15 Ų1560.7 Ų60.710%0.09731%0.313CS..G310 helixtrans-54-25.3177.5-2633.4000114.2I374 D378 L379 C441 Q444 Y448I374-P376 WeakPolarHBondContact O-CD 3.31Å; P376-D378 PolarHBondContact O-N 2.82Å; P376-L379 PolarHBondContact O-N 2.9Å; P376-L379 VanDerWaalsContact O-N 3.11Å; P376-C441 HydrophobicContact CG-CB 4.12Å; P376-Q444 VanDerWaalsContact CB-OE1 3.26Å; P376-Q444 HydrophobicContact CG-CB 3.82Å; P376-Y448 HydrophobicContact CB-CE2 4.36Å
377R84.3Confident77Confident206 Ų20665.6 Ų65.678%0.77734%0.338SS*.G310 helixtrans-67.6-23177.7-63175.7-68.2167.92113D375D375-R377 PolarHBondContact O-N 2.72Å; D375-R377 VanDerWaalsContact OD1-CB 3.26Å; D375-R377 WeakPolarHBondContact OD1-CB 3.35Å; D375-R377 VanDerWaalsContact OD1-CG 3.27Å; D375-R377 WeakPolarHBondContact OD1-CG 3.49Å; D375-R377 IonicContact OD1-CZ 3.7Å; D375-R377 PolarHBondContact OD1-N 3.44Å; D375-R377 IonicContact OD1-NE 3.7Å; D375-R377 PolarHBondContact OD1-NE 2.76Å; D375-R377 IonicContact OD1-NH2 3.15Å; D375-R377 IonicContact OD2-CZ 3.37Å; D375-R377 VanDerWaalsContact OD2-CZ 3.29Å; D375-R377 IonicContact OD2-NE 2.82Å; D375-R377 PolarHBondContact OD2-NE 2.91Å; D375-R377 VanDerWaalsContact OD2-NE 3.13Å; D375-R377 IonicContact OD2-NH2 3Å; D375-R377 PolarHBondContact OD2-NH2 2.76Å
378D84.4Confident77.6Confident63 Ų6367.1 Ų67.134%0.33736%0.356SS..G310 helixtrans-81.6-6.9175.4-60.4-25.1000111.9D375 P376 W398 Q399D375-D378 WeakPolarHBondContact O-CB 3.49Å; D375-D378 PolarHBondContact O-N 2.69Å; P376-D378 PolarHBondContact O-N 2.82Å; D378-W398 CarbonylContact O-C 3.56Å; D378-W398 WeakPolarHBondContact O-CA 3.33Å; D378-Q399 HydrophobicContact CB-CG 4.13Å; D378-Q399 PolarHBondContact O-N 2.69Å
379L89.4Confident78.2Confident11 Ų1172.8 Ų72.86%0.05838%0.381CS..EExtended strand (participates in β ladder)trans-100.7123.3-180-63.7176.1000111.3I374 P376 F381 W398 V404 I406 C441 Y448 V450I374-L379 HydrophobicContact CG2-CD1 4.13Å; I374-L379 HydrophobicContact CG2-CD2 4.14Å; I374-L379 HydrophobicContact CG2-CG 3.94Å; P376-L379 PolarHBondContact O-N 2.9Å; P376-L379 VanDerWaalsContact O-N 3.11Å; L379-F381 HydrophobicContact CB-CE2 4.42Å; L379-W398 HydrophobicContact CD2-CB 3.92Å; L379-W398 HydrophobicContact CD2-CG 4.15Å; L379-V404 HydrophobicContact CD2-CG2 4.28Å; L379-I406 HydrophobicContact CB-CD1 4.17Å; L379-I406 HydrophobicContact CD1-CD1 4.36Å; L379-I406 HydrophobicContact CD1-CG2 4.39Å; L379-I406 HydrophobicContact CD2-CD1 4.15Å; L379-I406 HydrophobicContact CD2-CG1 4.46Å; L379-I406 HydrophobicContact CG-CD1 4.48Å; L379-C441 VanDerWaalsContact CD1-SG 3.56Å; L379-Y448 HydrophobicContact CD1-CD2 4.29Å; L379-V450 HydrophobicContact CD1-CG2 3.81Å; L379-V450 HydrophobicContact CD2-CG1 4.31Å; L379-V450 HydrophobicContact CD2-CG2 4.22Å
380T92.1Very high79.1Confident73 Ų7372 Ų7245%0.44838%0.379SS..EExtended strand (participates in β ladder)trans-102.7118.7170.6-55.60000109.3I382 G396 K397T380-I382 HydrophobicContact CG2-CG1 4.3Å; T380-G396 CarbonylContact O-C 3.57Å; T380-G396 WeakPolarHBondContact O-CA 3.4Å; T380-K397 PolarHBondContact N-O 2.75Å; T380-K397 PolarHBondContact O-N 3.05Å
381F92.6Very high80.3Confident77 Ų7768.9 Ų68.934%0.33835%0.348SS..EExtended strand (participates in β ladder)trans-85.5125.3177-60.2-93.3000110.1L379 K394 I406 Y448L379-F381 HydrophobicContact CB-CE2 4.42Å; F381-K394 HydrophobicContact CB-CD 4.44Å; F381-K394 HydrophobicContact CD1-CB 4.24Å; F381-K394 HydrophobicContact CD1-CD 3.79Å; F381-I406 HydrophobicContact CD1-CD1 3.95Å; F381-I406 HydrophobicContact CE1-CB 4.22Å; F381-I406 HydrophobicContact CE1-CD1 3.93Å; F381-I406 HydrophobicContact CE1-CG2 3.67Å; F381-I406 HydrophobicContact CZ-CD1 4.47Å; F381-I406 HydrophobicContact CZ-CG2 4.29Å; F381-Y448 HydrophobicContact CZ-CD2 4.33Å; F381-Y448 HydrophobicContact CZ-CE1 4.44Å; F381-Y448 AromaticContact CZ-CE2 3.87Å; F381-Y448 HydrophobicContact CZ-CE2 3.87Å; F381-Y448 AromaticContact CZ-CZ 3.95Å
382I92.3Very high81.5Confident89 Ų8967.5 Ų67.546%0.45634%0.339SS..EExtended strand (participates in β ladder)trans-112.9-54.7-173-61.5171.5000111.4T380 Y395 K397T380-I382 HydrophobicContact CG2-CG1 4.3Å; I382-Y395 HydrophobicContact CB-CD1 3.71Å; I382-Y395 HydrophobicContact CB-CE1 3.85Å; I382-Y395 HydrophobicContact CD1-CD1 4.31Å; I382-Y395 HydrophobicContact CD1-CE1 3.67Å; I382-Y395 HydrophobicContact CG1-CE1 4.36Å; I382-Y395 HydrophobicContact CG2-CD1 3.81Å; I382-Y395 HydrophobicContact CG2-CE1 3.73Å; I382-Y395 PolarHBondContact N-O 2.96Å; I382-K397 HydrophobicContact CD1-CB 4.29Å; I382-K397 HydrophobicContact CD1-CD 4.16Å; I382-K397 HydrophobicContact CD1-CG 3.7Å
383K92.8Very high82.4Confident138 Ų13866.2 Ų66.260%0.634%0.339SS*.EExtended strand (participates in β ladder)trans-144.2142-172.5-175.4-174.8171.8-174.20111.3K394 Y395K383-K394 CarbonylContact O-C 3.4Å; K383-K394 VanDerWaalsContact O-CA 3.26Å; K383-K394 WeakPolarHBondContact O-CA 3.45Å; K383-Y395 HydrophobicContact CB-CD1 4.18Å; K383-Y395 PolarHBondContact N-O 2.91Å; K383-Y395 VanDerWaalsContact N-O 3.08Å; K383-Y395 PolarHBondContact O-N 3.16Å
384E93Very high83.2Confident105 Ų10567 Ų6749%0.49134%0.342SS..EExtended strand (participates in β ladder)trans-73.7130.2168.8-170.1169.1139.600110.9V392E384-V392 HydrophobicContact CG-CG1 3.74Å
385L87.1Confident83.8Confident81 Ų8168.7 Ų68.742%0.42435%0.348SS..EExtended strand (participates in β ladder)trans-98.8-34.2178.1-65.2177.1000111.8V393 F453L385-V393 HydrophobicContact CB-CG1 4.35Å; L385-V393 HydrophobicContact CD1-CG1 4.28Å; L385-V393 PolarHBondContact N-O 3.28Å; L385-F453 HydrophobicContact CD1-CD2 4.01Å; L385-F453 HydrophobicContact CD1-CE2 3.8Å; L385-F453 HydrophobicContact CD2-CE2 4.11Å
386G82.1Confident84.4Confident30 Ų3066.2 Ų66.231%0.30934%0.335SS..EExtended strand (participates in β ladder)trans-178.3165.6177.700000113.4V393G386-V393 PolarHBondContact N-O 3.3Å; G386-V393 PolarHBondContact O-N 3.09Å
387N78.8Confident84.5Confident108 Ų10868.7 Ų68.758%0.57834%0.344SS*.EExtended strand (participates in β ladder)trans-127.8106.1177.9-173.7-8.2000109.1V392N387-V392 HydrophobicContact CB-CG2 4.47Å
388G66.3Low84.5Confident40 Ų4059.4 Ų59.441%0.41231%0.309SS..EExtended strand (participates in β ladder)trans-102.9-179.9-17700000113.4F390 G391 K410G388-F390 PolarHBondContact O-N 3.38Å; G388-G391 PolarHBondContact N-O 3.31Å; G388-G391 PolarHBondContact O-N 3.33Å; G388-K410 PolarHBondContact O-NZ 2.87Å
389Q61.9Low84.3Confident123 Ų12360.7 Ų60.758%0.57531%0.313SS*.THydrogen-bonded Turntrans-53.3-39.9175.5178.9172-31.900111.8K410Q389-K410 PolarHBondContact O-NZ 3.43Å
390F62.8Low83.6Confident58 Ų5862.3 Ų62.325%0.25433%0.332SS..THydrogen-bonded Turntrans-91.2-8.2-172.6-53.1-72.5000114.2G388 K410 L520G388-F390 PolarHBondContact O-N 3.38Å; F390-K410 PolarHBondContact O-N 2.87Å; F390-L520 HydrophobicContact CD1-CD1 3.6Å; F390-L520 HydrophobicContact CD2-CD1 3.57Å; F390-L520 HydrophobicContact CE1-CD1 3.51Å; F390-L520 HydrophobicContact CE2-CD1 3.48Å; F390-L520 VanDerWaalsContact CE2-CD1 3.48Å; F390-L520 HydrophobicContact CG-CD1 3.63Å; F390-L520 HydrophobicContact CZ-CD1 3.45Å; F390-L520 VanDerWaalsContact CZ-CD1 3.45Å
391G73.7Confident82.9Confident3 Ų366 Ų663%0.03134%0.344CS..EExtended strand (participates in β ladder)trans141.1-168177.400000114.3G388 M408G388-G391 PolarHBondContact N-O 3.31Å; G388-G391 PolarHBondContact O-N 3.33Å; G391-M408 VanDerWaalsContact CA-O 3.27Å; G391-M408 WeakPolarHBondContact CA-O 3.32Å
392V85.1Confident82.1Confident30 Ų3066 Ų6618%0.18235%0.345CS..EExtended strand (participates in β ladder)trans-94.8133.8-174.5-178.10000109.4E384 N387 K394 M408E384-V392 HydrophobicContact CG-CG1 3.74Å; N387-V392 HydrophobicContact CB-CG2 4.47Å; V392-K394 HydrophobicContact CG1-CG 4.09Å; V392-M408 HydrophobicContact CB-SD 4.39Å; V392-M408 PolarHBondContact N-O 3.5Å; V392-M408 WeakPolarHBondContact O-CB 3.3Å; V392-M408 PolarHBondContact O-N 3.31Å
393V89.8Confident81.9Confident41 Ų4165.2 Ų65.225%0.24834%0.342CS..EExtended strand (participates in β ladder)trans-105128.2173.6-173.60000108.4L385 G386 A405 I406 K407L385-V393 HydrophobicContact CB-CG1 4.35Å; L385-V393 HydrophobicContact CD1-CG1 4.28Å; L385-V393 PolarHBondContact N-O 3.28Å; G386-V393 PolarHBondContact N-O 3.3Å; G386-V393 PolarHBondContact O-N 3.09Å; V393-A405 HydrophobicContact CG1-CB 4.5Å; V393-I406 WeakPolarHBondContact CA-O 3.42Å; V393-K407 HydrophobicContact CG2-CB 4.24Å; V393-K407 HydrophobicContact CG2-CD 4.41Å; V393-K407 HydrophobicContact CG2-CG 4Å
394K92.7Very high81.8Confident60 Ų6058.7 Ų58.726%0.26131%0.313SS..EExtended strand (participates in β ladder)trans-121.8142.2178.3-63.8-171173.1-177.80110.8F381 K383 V392 I406 M408F381-K394 HydrophobicContact CB-CD 4.44Å; F381-K394 HydrophobicContact CD1-CB 4.24Å; F381-K394 HydrophobicContact CD1-CD 3.79Å; K383-K394 CarbonylContact O-C 3.4Å; K383-K394 VanDerWaalsContact O-CA 3.26Å; K383-K394 WeakPolarHBondContact O-CA 3.45Å; V392-K394 HydrophobicContact CG1-CG 4.09Å; K394-I406 PolarHBondContact N-O 3.42Å; K394-I406 PolarHBondContact O-N 2.98Å; K394-M408 HydrophobicContact CD-SD 4.15Å
395Y94.1Very high81.8Confident40 Ų4054.1 Ų54.116%0.15729%0.294CS..EExtended strand (participates in β ladder)trans-75.9137.2161.2165.8-112.5000108.8I382 K383 D403 F453I382-Y395 HydrophobicContact CB-CD1 3.71Å; I382-Y395 HydrophobicContact CB-CE1 3.85Å; I382-Y395 HydrophobicContact CD1-CD1 4.31Å; I382-Y395 HydrophobicContact CD1-CE1 3.67Å; I382-Y395 HydrophobicContact CG1-CE1 4.36Å; I382-Y395 HydrophobicContact CG2-CD1 3.81Å; I382-Y395 HydrophobicContact CG2-CE1 3.73Å; I382-Y395 PolarHBondContact N-O 2.96Å; K383-Y395 HydrophobicContact CB-CD1 4.18Å; K383-Y395 PolarHBondContact N-O 2.91Å; K383-Y395 VanDerWaalsContact N-O 3.08Å; K383-Y395 PolarHBondContact O-N 3.16Å; Y395-D403 HydrophobicContact CE2-CB 3.94Å; Y395-D403 WeakPolarHBondContact CE2-OD1 3.35Å; Y395-D403 PolarHBondContact OH-OD1 3.15Å; Y395-F453 HydrophobicContact CD2-CD1 4.02Å; Y395-F453 AromaticContact CD2-CD2 3.74Å; Y395-F453 HydrophobicContact CD2-CD2 3.74Å; Y395-F453 HydrophobicContact CD2-CE1 4.09Å; Y395-F453 AromaticContact CD2-CE2 3.83Å; Y395-F453 HydrophobicContact CD2-CE2 3.83Å; Y395-F453 AromaticContact CD2-CG 3.84Å; Y395-F453 HydrophobicContact CD2-CG 3.84Å; Y395-F453 AromaticContact CD2-CZ 4Å; Y395-F453 HydrophobicContact CD2-CZ 4Å; Y395-F453 AromaticContact CE2-CD1 3.98Å; Y395-F453 HydrophobicContact CE2-CD1 3.98Å; Y395-F453 HydrophobicContact CE2-CE1 4.1Å; Y395-F453 HydrophobicContact CE2-CG 4.19Å; Y395-F453 HydrophobicContact CE2-CZ 4.43Å; Y395-F453 HydrophobicContact CG-CE2 4.34Å
396G92.8Very high82Confident0 Ų050.3 Ų50.30%027%0.274CS..EExtended strand (participates in β ladder)trans-154.6-176.4177.900000112.5T380 V404T380-G396 CarbonylContact O-C 3.57Å; T380-G396 WeakPolarHBondContact O-CA 3.4Å; G396-V404 PolarHBondContact N-O 3.35Å; G396-V404 PolarHBondContact O-N 2.98Å
397K87.3Confident82.2Confident66 Ų6650 Ų5029%0.28726%0.264SS..EExtended strand (participates in β ladder)trans-119.9134.9171.4-74.9-171.7177.4-148.20111T380 I382 G400 H402 D403T380-K397 PolarHBondContact N-O 2.75Å; T380-K397 PolarHBondContact O-N 3.05Å; I382-K397 HydrophobicContact CD1-CB 4.29Å; I382-K397 HydrophobicContact CD1-CD 4.16Å; I382-K397 HydrophobicContact CD1-CG 3.7Å; K397-G400 WeakPolarHBondContact CD-O 3.23Å; K397-H402 CarbonylContact C-O 3.45Å; K397-H402 WeakPolarHBondContact CA-O 3.47Å; K397-D403 WeakPolarHBondContact CE-OD1 3.41Å
398W83.1Confident82.6Confident12 Ų1246.7 Ų46.75%0.04525%0.245CC..EExtended strand (participates in β ladder)trans-94.8130.8168.3179.647.1000109.7M206 L367 D378 L379 G400 Q401 H402 V404M206-W398 HydrophobicContact SD-CH2 4.15Å; M206-W398 HydrophobicContact SD-CZ3 4.42Å; L367-W398 HydrophobicContact CB-CH2 3.67Å; L367-W398 HydrophobicContact CB-CZ2 3.94Å; L367-W398 HydrophobicContact CD2-CD2 3.95Å; L367-W398 HydrophobicContact CD2-CE3 3.79Å; L367-W398 HydrophobicContact CD2-CH2 3.14Å; L367-W398 HydrophobicContact CD2-CZ2 3.28Å; L367-W398 HydrophobicContact CD2-CZ3 3.39Å; L367-W398 HydrophobicContact CG-CH2 3.97Å; L367-W398 HydrophobicContact CG-CZ2 4.12Å; D378-W398 CarbonylContact O-C 3.56Å; D378-W398 WeakPolarHBondContact O-CA 3.33Å; L379-W398 HydrophobicContact CD2-CB 3.92Å; L379-W398 HydrophobicContact CD2-CG 4.15Å; W398-G400 PolarHBondContact O-N 2.96Å; W398-Q401 PolarHBondContact O-N 3.1Å; W398-Q401 VanDerWaalsContact O-N 3.15Å; W398-H402 HydrophobicContact CB-CB 4.47Å; W398-H402 HydrophobicContact CE3-CB 4.43Å; W398-H402 PolarHBondContact N-O 2.74Å; W398-H402 PolarHBondContact O-N 3Å; W398-V404 HydrophobicContact CB-CG1 3.84Å; W398-V404 HydrophobicContact CB-CG2 4.15Å
399Q80.4Confident83.1Confident90 Ų9045.8 Ų45.842%0.42123%0.231SC..THydrogen-bonded Turntrans51.427.8-172.3-61.8179.8-4.600113.8D378 Q401D378-Q399 HydrophobicContact CB-CG 4.13Å; D378-Q399 PolarHBondContact O-N 2.69Å; Q399-Q401 PolarHBondContact O-N 2.84Å; Q399-Q401 VanDerWaalsContact O-N 3.11Å
400G73.9Confident83.5Confident44 Ų4444.8 Ų44.845%0.45423%0.225SC..THydrogen-bonded Turntrans70-0.6-179.400000115.6K397 W398K397-G400 WeakPolarHBondContact CD-O 3.23Å; W398-G400 PolarHBondContact O-N 2.96Å
401Q77.3Confident83.6Confident150 Ų15048.7 Ų48.770%0.70124%0.244SC*.THydrogen-bonded Turntrans-118.7-45.3-174.3-62.3-169.511.600113.1W398 Q399W398-Q401 PolarHBondContact O-N 3.1Å; W398-Q401 VanDerWaalsContact O-N 3.15Å; Q399-Q401 PolarHBondContact O-N 2.84Å; Q399-Q401 VanDerWaalsContact O-N 3.11Å
402H76.5Confident82.8Confident78 Ų7852.5 Ų52.536%0.36128%0.283SS..EExtended strand (participates in β ladder)trans-91.9123.8-169.9-61.4-68.9000112.1K397 W398 V404K397-H402 CarbonylContact C-O 3.45Å; K397-H402 WeakPolarHBondContact CA-O 3.47Å; W398-H402 HydrophobicContact CB-CB 4.47Å; W398-H402 HydrophobicContact CE3-CB 4.43Å; W398-H402 PolarHBondContact N-O 2.74Å; W398-H402 PolarHBondContact O-N 3Å; H402-V404 PolarHBondContact O-N 3.13Å
403D87.4Confident81.3Confident73 Ų7354.5 Ų54.539%0.3930%0.298SS..EExtended strand (participates in β ladder)trans-69.2125.4175.8-70.5-39.4000110.9Y395 K397 F453Y395-D403 HydrophobicContact CE2-CB 3.94Å; Y395-D403 WeakPolarHBondContact CE2-OD1 3.35Å; Y395-D403 PolarHBondContact OH-OD1 3.15Å; K397-D403 WeakPolarHBondContact CE-OD1 3.41Å; D403-F453 HydrophobicContact CB-CB 4.23Å; D403-F453 HydrophobicContact CB-CD1 4.15Å
404V91.7Very high79.6Confident0 Ų055.7 Ų55.70%030%0.302CS..EExtended strand (participates in β ladder)trans-136150.7-176-65.40000111.9L379 G396 W398 H402 I406 Y438 V450L379-V404 HydrophobicContact CD2-CG2 4.28Å; G396-V404 PolarHBondContact N-O 3.35Å; G396-V404 PolarHBondContact O-N 2.98Å; W398-V404 HydrophobicContact CB-CG1 3.84Å; W398-V404 HydrophobicContact CB-CG2 4.15Å; H402-V404 PolarHBondContact O-N 3.13Å; V404-I406 HydrophobicContact CG2-CD1 4.07Å; V404-I406 HydrophobicContact CG2-CG1 3.85Å; V404-Y438 HydrophobicContact CG1-CD2 3.91Å; V404-Y438 HydrophobicContact CG1-CE2 4.01Å; V404-V450 HydrophobicContact CB-CG1 3.73Å; V404-V450 HydrophobicContact CG1-CG1 3.86Å; V404-V450 HydrophobicContact CG2-CG1 4.07Å
405A92.5Very high77.9Confident10 Ų1055.5 Ų55.58%0.08331%0.309CS..EExtended strand (participates in β ladder)trans-97.5127.7164.700000109.1V393 V450 T451V393-A405 HydrophobicContact CG1-CB 4.5Å; A405-V450 WeakPolarHBondContact O-CA 3.48Å; A405-T451 PolarHBondContact N-O 3.21Å; A405-T451 PolarHBondContact O-N 3.47Å
406I91.3Very high76.3Confident0 Ų057.2 Ų57.20%032%0.318CS..EExtended strand (participates in β ladder)trans-116.4106.8-175.3-51.9164.3000107.8L379 F381 V393 K394 V404 Y448 I449L379-I406 HydrophobicContact CB-CD1 4.17Å; L379-I406 HydrophobicContact CD1-CD1 4.36Å; L379-I406 HydrophobicContact CD1-CG2 4.39Å; L379-I406 HydrophobicContact CD2-CD1 4.15Å; L379-I406 HydrophobicContact CD2-CG1 4.46Å; L379-I406 HydrophobicContact CG-CD1 4.48Å; F381-I406 HydrophobicContact CD1-CD1 3.95Å; F381-I406 HydrophobicContact CE1-CB 4.22Å; F381-I406 HydrophobicContact CE1-CD1 3.93Å; F381-I406 HydrophobicContact CE1-CG2 3.67Å; F381-I406 HydrophobicContact CZ-CD1 4.47Å; F381-I406 HydrophobicContact CZ-CG2 4.29Å; V393-I406 WeakPolarHBondContact CA-O 3.42Å; K394-I406 PolarHBondContact N-O 3.42Å; K394-I406 PolarHBondContact O-N 2.98Å; V404-I406 HydrophobicContact CG2-CD1 4.07Å; V404-I406 HydrophobicContact CG2-CG1 3.85Å; I406-Y448 HydrophobicContact CG2-CD1 4.32Å; I406-Y448 HydrophobicContact CG2-CG 4.07Å; I406-I449 WeakPolarHBondContact CA-O 3.47Å
407K87.8Confident74.7Confident23 Ų2363 Ų6310%0.135%0.349CS..EExtended strand (participates in β ladder)trans-94.4117177.2-176.6174.9-166.9175.90109.8V393 I409 Y448 I449 D517V393-K407 HydrophobicContact CG2-CB 4.24Å; V393-K407 HydrophobicContact CG2-CD 4.41Å; V393-K407 HydrophobicContact CG2-CG 4Å; K407-I409 HydrophobicContact CD-CD1 4.28Å; K407-I409 HydrophobicContact CG-CD1 4.1Å; K407-Y448 CarbonylContact O-C 3.49Å; K407-Y448 WeakPolarHBondContact O-CA 3.31Å; K407-I449 HydrophobicContact CB-CB 4.27Å; K407-I449 PolarHBondContact N-O 3.17Å; K407-I449 PolarHBondContact O-N 3.29Å; K407-D517 IonicContact NZ-OD1 2.75Å; K407-D517 PolarHBondContact NZ-OD1 3.05Å; K407-D517 IonicContact NZ-OD2 3.65Å; K407-D517 PolarHBondContact NZ-OD2 3.43Å
408M85.9Confident73.3Confident39 Ų3964 Ų6419%0.19236%0.357CS..EExtended strand (participates in β ladder)trans-86.8119.3176.7-51.2175.571.600109.2G391 V392 K394 P446 Y448G391-M408 VanDerWaalsContact CA-O 3.27Å; G391-M408 WeakPolarHBondContact CA-O 3.32Å; V392-M408 HydrophobicContact CB-SD 4.39Å; V392-M408 PolarHBondContact N-O 3.5Å; V392-M408 WeakPolarHBondContact O-CB 3.3Å; V392-M408 PolarHBondContact O-N 3.31Å; K394-M408 HydrophobicContact CD-SD 4.15Å; M408-P446 HydrophobicContact CE-CG 3.66Å; M408-Y448 HydrophobicContact CB-CD1 4.16Å; M408-Y448 HydrophobicContact CB-CE1 4.15Å; M408-Y448 HydrophobicContact CE-CE1 3.79Å; M408-Y448 HydrophobicContact CG-CD1 3.83Å; M408-Y448 HydrophobicContact CG-CE1 3.69Å; M408-Y448 HydrophobicContact SD-CE1 4.47Å
409I77.3Confident72.5Confident21 Ų2164 Ų6411%0.10836%0.358CS..EExtended strand (participates in β ladder)trans-86.8129.4-179.6-55.1-59.5000109.9K407 S413 F419 P446 I447 I449K407-I409 HydrophobicContact CD-CD1 4.28Å; K407-I409 HydrophobicContact CG-CD1 4.1Å; I409-S413 WeakPolarHBondContact CG2-OG 3.5Å; I409-F419 HydrophobicContact CG1-CE2 4.15Å; I409-P446 WeakPolarHBondContact O-CB 3.49Å; I409-I447 HydrophobicContact CB-CB 4.42Å; I409-I447 PolarHBondContact N-O 3.3Å; I409-I449 HydrophobicContact CD1-CD1 3.84Å; I409-I449 HydrophobicContact CD1-CG1 4.27Å; I409-I449 HydrophobicContact CG1-CD1 4.28Å; I409-I449 HydrophobicContact CG1-CG1 4.25Å
410K69.3Low71.8Confident102 Ų10261.3 Ų61.344%0.44335%0.346SS..PPolyproline II helixtrans-65.9140.7176.8-74173.2177.8157.90111G388 Q389 F390 S413G388-K410 PolarHBondContact O-NZ 2.87Å; Q389-K410 PolarHBondContact O-NZ 3.43Å; F390-K410 PolarHBondContact O-N 2.87Å; K410-S413 PolarHBondContact O-OG 2.85Å; K410-S413 VanDerWaalsContact O-OG 3.04Å
411E66.8Low71.2Confident140 Ų14065.4 Ų65.465%0.65435%0.353SS*.THydrogen-bonded Turntrans-61.6140.8176.2-70.9-176.3175.500111.8R445E411-R445 WeakPolarHBondContact OE1-CD 3.32Å
412G56.8Low70.6Confident84 Ų8460.6 Ų60.687%0.86633%0.33SS*.THydrogen-bonded Turntrans84.43.4177.100000115.9
413S52.1Low70.3Confident71 Ų7157 Ų5750%0.49731%0.314SS..SBendtrans-79.6-26.8177.960.50000114.6I409 K410I409-S413 WeakPolarHBondContact CG2-OG 3.5Å; K410-S413 PolarHBondContact O-OG 2.85Å; K410-S413 VanDerWaalsContact O-OG 3.04Å
414M55Low69.4Low67 Ų6757.9 Ų57.933%0.3332%0.315SS..SBendtrans-157.4156.7-177.2-166.8-178.7-80.500110D418 F419 E422 L520M414-D418 HydrophobicContact CG-CB 4.37Å; M414-F419 HydrophobicContact CG-CB 4.43Å; M414-F419 HydrophobicContact SD-CB 3.73Å; M414-F419 HydrophobicContact SD-CD2 4.11Å; M414-F419 HydrophobicContact SD-CG 4.45Å; M414-E422 VanDerWaalsContact CE-OE2 3.32Å; M414-E422 WeakPolarHBondContact CE-OE2 3.41Å; M414-L520 HydrophobicContact CE-CD2 4.12Å
415S57.2Low68.2Low56 Ų5661 Ų6139%0.39233%0.331SS..  trans-73.3147.2169.192.20000110.1D418 F419S415-D418 WeakPolarHBondContact OG-CB 3.4Å; S415-D418 PolarHBondContact OG-N 2.83Å; S415-D418 PolarHBondContact OG-OD2 3.44Å; S415-F419 WeakPolarHBondContact O-CB 3.42Å; S415-F419 PolarHBondContact O-N 3.43Å
416E60.5Low67.1Low76 Ų7661.3 Ų61.336%0.35533%0.331SS..Hα-helixtrans-68.9-37-174.8-57.1-170127.400112.9F419 I420 R445 I447E416-F419 PolarHBondContact O-N 3.09Å; E416-I420 WeakPolarHBondContact O-CB 3.4Å; E416-I420 VanDerWaalsContact O-CG1 3.27Å; E416-I420 WeakPolarHBondContact O-CG1 3.2Å; E416-I420 PolarHBondContact O-N 2.84Å; E416-R445 IonicContact OE1-CZ 3.85Å; E416-R445 IonicContact OE1-NH1 3.9Å; E416-R445 PolarHBondContact OE1-NH1 3.39Å; E416-R445 IonicContact OE1-NH2 3.8Å; E416-R445 PolarHBondContact OE1-NH2 2.98Å; E416-R445 IonicContact OE2-NH2 3.06Å; E416-R445 PolarHBondContact OE2-NH2 3.24Å; E416-R445 VanDerWaalsContact OE2-NH2 3.15Å; E416-I447 HydrophobicContact CG-CD1 4.16Å
417D57.7Low66.1Low122 Ų12262.7 Ų62.765%0.65234%0.337SS*.Hα-helixtrans-65.5-45.5178.8-67.3-29.7000110.4F419 I420 E421D417-F419 VanDerWaalsContact C-N 3.32Å; D417-F419 PolarHBondContact O-N 3.36Å; D417-I420 PolarHBondContact O-N 3.22Å; D417-E421 WeakPolarHBondContact O-CG 3.26Å; D417-E421 PolarHBondContact O-N 2.95Å
418D58.4Low65.3Low85 Ų8568.8 Ų68.846%0.45536%0.364SS..Hα-helixtrans-62.6-41.2176.1-62.9-34.6000110.7M414 S415 E421 E422M414-D418 HydrophobicContact CG-CB 4.37Å; S415-D418 WeakPolarHBondContact OG-CB 3.4Å; S415-D418 PolarHBondContact OG-N 2.83Å; S415-D418 PolarHBondContact OG-OD2 3.44Å; D418-E421 PolarHBondContact O-N 3.39Å; D418-E422 WeakPolarHBondContact O-CB 3.41Å; D418-E422 WeakPolarHBondContact O-CG 3.27Å; D418-E422 PolarHBondContact O-N 3.48Å
419F65.8Low64.8Low14 Ų1467.2 Ų67.26%0.06136%0.357CS..Hα-helixtrans-62.1-44.8177.2176-90.4000112.5I409 M414 S415 E416 D417 E422 A423 V440 T442 I447 I449I409-F419 HydrophobicContact CG1-CE2 4.15Å; M414-F419 HydrophobicContact CG-CB 4.43Å; M414-F419 HydrophobicContact SD-CB 3.73Å; M414-F419 HydrophobicContact SD-CD2 4.11Å; M414-F419 HydrophobicContact SD-CG 4.45Å; S415-F419 WeakPolarHBondContact O-CB 3.42Å; S415-F419 PolarHBondContact O-N 3.43Å; E416-F419 PolarHBondContact O-N 3.09Å; D417-F419 VanDerWaalsContact C-N 3.32Å; D417-F419 PolarHBondContact O-N 3.36Å; F419-E422 PolarHBondContact O-N 3.34Å; F419-A423 VanDerWaalsContact O-CB 3.22Å; F419-A423 WeakPolarHBondContact O-CB 3.49Å; F419-A423 PolarHBondContact O-N 3.07Å; F419-V440 HydrophobicContact CE1-CB 4.1Å; F419-V440 HydrophobicContact CE1-CG1 3.93Å; F419-V440 HydrophobicContact CE1-CG2 4.49Å; F419-V440 HydrophobicContact CZ-CG1 4Å; F419-T442 HydrophobicContact CD1-CG2 4.17Å; F419-T442 HydrophobicContact CE1-CG2 4.03Å; F419-I447 HydrophobicContact CD1-CD1 4.41Å; F419-I447 HydrophobicContact CD1-CG2 3.97Å; F419-I447 HydrophobicContact CE1-CG2 3.29Å; F419-I447 HydrophobicContact CE2-CG2 4.31Å; F419-I447 HydrophobicContact CZ-CG2 3.47Å; F419-I447 VanDerWaalsContact CZ-CG2 3.47Å; F419-I449 HydrophobicContact CE2-CD1 3.85Å; F419-I449 HydrophobicContact CE2-CG1 3.92Å; F419-I449 HydrophobicContact CZ-CD1 4.04Å; F419-I449 HydrophobicContact CZ-CG1 3.58Å
420I65.6Low64.9Low33 Ų3369.2 Ų69.217%0.16936%0.363CS..Hα-helixtrans-66.1-41.9179.6-72.5164.1000110.7W372 E416 D417 K424 T442W372-I420 HydrophobicContact CH2-CG1 4.46Å; W372-I420 HydrophobicContact CH2-CG2 3.75Å; W372-I420 HydrophobicContact CZ2-CG2 4.49Å; W372-I420 HydrophobicContact CZ3-CG1 4.37Å; W372-I420 HydrophobicContact CZ3-CG2 3.92Å; E416-I420 WeakPolarHBondContact O-CB 3.4Å; E416-I420 VanDerWaalsContact O-CG1 3.27Å; E416-I420 WeakPolarHBondContact O-CG1 3.2Å; E416-I420 PolarHBondContact O-N 2.84Å; D417-I420 PolarHBondContact O-N 3.22Å; I420-K424 HydrophobicContact CG2-CD 4.18Å; I420-K424 WeakPolarHBondContact O-CB 3.35Å; I420-K424 VanDerWaalsContact O-CG 3.31Å; I420-K424 WeakPolarHBondContact O-CG 3.36Å; I420-K424 PolarHBondContact O-N 2.88Å; I420-T442 HydrophobicContact CD1-CG2 4.12Å; I420-T442 HydrophobicContact CG1-CG2 3.75Å
421E62.3Low65.7Low130 Ų13067.2 Ų67.261%0.60736%0.355SS*.Hα-helixtrans-63.2-46.8176.1-74.2-173.2-179.400111.2D417 D418 K424 I425D417-E421 WeakPolarHBondContact O-CG 3.26Å; D417-E421 PolarHBondContact O-N 2.95Å; D418-E421 PolarHBondContact O-N 3.39Å; E421-K424 PolarHBondContact O-N 3.29Å; E421-I425 WeakPolarHBondContact O-CG1 3.47Å; E421-I425 PolarHBondContact O-N 3.48Å
422E65.5Low66.6Low48 Ų4867 Ų6722%0.22435%0.354CS..Hα-helixtrans-61.4-46.6176.3-75-176.4179.800111.4M414 D418 F419 K424 I425 M426M414-E422 VanDerWaalsContact CE-OE2 3.32Å; M414-E422 WeakPolarHBondContact CE-OE2 3.41Å; D418-E422 WeakPolarHBondContact O-CB 3.41Å; D418-E422 WeakPolarHBondContact O-CG 3.27Å; D418-E422 PolarHBondContact O-N 3.48Å; F419-E422 PolarHBondContact O-N 3.34Å; E422-K424 VanDerWaalsContact C-N 3.35Å; E422-K424 PolarHBondContact O-N 2.84Å; E422-I425 PolarHBondContact O-N 3.43Å; E422-I425 VanDerWaalsContact O-N 3.13Å; E422-M426 VanDerWaalsContact O-CG 3.28Å; E422-M426 WeakPolarHBondContact O-CG 3.35Å; E422-M426 PolarHBondContact O-N 2.99Å
423A69.8Low68.4Low3 Ų363.2 Ų63.23%0.02531%0.314CS..Hα-helixtrans-59.1-42.2178.300000112.5F419 I425 M426 M427 V440F419-A423 VanDerWaalsContact O-CB 3.22Å; F419-A423 WeakPolarHBondContact O-CB 3.49Å; F419-A423 PolarHBondContact O-N 3.07Å; A423-I425 VanDerWaalsContact C-N 3.29Å; A423-I425 PolarHBondContact O-N 3.22Å; A423-M426 PolarHBondContact O-N 3.43Å; A423-M427 VanDerWaalsContact O-CG 3.27Å; A423-M427 WeakPolarHBondContact O-CG 3.39Å; A423-M427 PolarHBondContact O-N 3.17Å; A423-V440 HydrophobicContact CB-CG1 3.71Å; A423-V440 HydrophobicContact CB-CG2 4.31Å
424K67.3Low70.3Confident91 Ų9159.9 Ų59.940%0.39629%0.29SS..Hα-helixtrans-63.3-34.1177.3-78.1173.2-179.3172.70113W372 I420 E421 E422W372-K424 HydrophobicContact CD2-CG 4.5Å; I420-K424 HydrophobicContact CG2-CD 4.18Å; I420-K424 WeakPolarHBondContact O-CB 3.35Å; I420-K424 VanDerWaalsContact O-CG 3.31Å; I420-K424 WeakPolarHBondContact O-CG 3.36Å; I420-K424 PolarHBondContact O-N 2.88Å; E421-K424 PolarHBondContact O-N 3.29Å; E422-K424 VanDerWaalsContact C-N 3.35Å; E422-K424 PolarHBondContact O-N 2.84Å
425I67.5Low72Confident67 Ų6756.8 Ų56.834%0.34428%0.275SS..Hα-helixtrans-77.3-42.3176.4-52.9163000109.7E421 E422 A423 M427 K428 Y495E421-I425 WeakPolarHBondContact O-CG1 3.47Å; E421-I425 PolarHBondContact O-N 3.48Å; E422-I425 PolarHBondContact O-N 3.43Å; E422-I425 VanDerWaalsContact O-N 3.13Å; A423-I425 VanDerWaalsContact C-N 3.29Å; A423-I425 PolarHBondContact O-N 3.22Å; I425-M427 VanDerWaalsContact C-N 3.25Å; I425-M427 PolarHBondContact O-N 2.85Å; I425-K428 VanDerWaalsContact O-CB 3.31Å; I425-K428 WeakPolarHBondContact O-CB 3.32Å; I425-K428 PolarHBondContact O-N 2.91Å; I425-Y495 VanDerWaalsContact CB-OH 3.23Å; I425-Y495 WeakPolarHBondContact CB-OH 3.4Å; I425-Y495 HydrophobicContact CG2-CE2 3.93Å; I425-Y495 WeakPolarHBondContact CG2-OH 3.32Å
426M69.3Low73.3Confident16 Ų1654.8 Ų54.88%0.07926%0.26CS..Hα-helixtrans-57.8-36.4175-70.7173.570.300113.3E422 A423 K428 L429 L437 F518 G519E422-M426 VanDerWaalsContact O-CG 3.28Å; E422-M426 WeakPolarHBondContact O-CG 3.35Å; E422-M426 PolarHBondContact O-N 2.99Å; A423-M426 PolarHBondContact O-N 3.43Å; M426-K428 PolarHBondContact O-N 3.32Å; M426-K428 VanDerWaalsContact O-N 3.16Å; M426-L429 WeakPolarHBondContact O-CB 3.48Å; M426-L429 PolarHBondContact O-N 3.46Å; M426-L437 HydrophobicContact CB-CD2 3.69Å; M426-L437 HydrophobicContact CE-CD2 4.08Å; M426-L437 HydrophobicContact SD-CD2 4.32Å; M426-F518 HydrophobicContact CB-CE2 4.4Å; M426-F518 HydrophobicContact CE-CD2 3.87Å; M426-F518 HydrophobicContact CE-CE2 3.76Å; M426-F518 HydrophobicContact CG-CD2 4.48Å; M426-F518 HydrophobicContact CG-CE2 4.46Å; M426-G519 WeakPolarHBondContact SD-CA 2.89Å
427M71.2Confident74.5Confident28 Ų2851.4 Ų51.414%0.13824%0.244CC..THydrogen-bonded Turntrans-62.5-19.6176.8-77.3-177.575.100113.4W372 A423 I425 L437 Y438W372-M427 HydrophobicContact CB-CE 3.65Å; W372-M427 HydrophobicContact CB-SD 3.39Å; W372-M427 WeakPolarHBondContact CB-SD 3.44Å; A423-M427 VanDerWaalsContact O-CG 3.27Å; A423-M427 WeakPolarHBondContact O-CG 3.39Å; A423-M427 PolarHBondContact O-N 3.17Å; I425-M427 VanDerWaalsContact C-N 3.25Å; I425-M427 PolarHBondContact O-N 2.85Å; M427-L437 HydrophobicContact CB-CD2 4.5Å; M427-L437 HydrophobicContact CG-CD2 3.53Å; M427-L437 HydrophobicContact CG-CG 3.84Å; M427-Y438 WeakPolarHBondContact CE-O 3.06Å
428K70.3Confident75.6Confident151 Ų15147 Ų4766%0.65722%0.218SC*.THydrogen-bonded Turntrans-83.8-18.8174.3-58.5178.3-178.9-178.50112.6I425 M426 R430I425-K428 VanDerWaalsContact O-CB 3.31Å; I425-K428 WeakPolarHBondContact O-CB 3.32Å; I425-K428 PolarHBondContact O-N 2.91Å; M426-K428 PolarHBondContact O-N 3.32Å; M426-K428 VanDerWaalsContact O-N 3.16Å; K428-R430 PolarHBondContact O-N 2.77Å
429L76.2Confident76.7Confident7 Ų743 Ų434%0.03720%0.197CC..  trans-75.6119.7177.3-59176.9000109M426 Y489 L490 Q493 Y495 F518M426-L429 WeakPolarHBondContact O-CB 3.48Å; M426-L429 PolarHBondContact O-N 3.46Å; L429-Y489 HydrophobicContact CB-CE1 4.18Å; L429-Y489 HydrophobicContact CD2-CE1 4.07Å; L429-L490 HydrophobicContact CD1-CD2 3.9Å; L429-Q493 HydrophobicContact CD2-CB 3.82Å; L429-Q493 HydrophobicContact CD2-CG 3.82Å; L429-Y495 HydrophobicContact CD1-CD1 4.21Å; L429-Y495 HydrophobicContact CD1-CD2 4.06Å; L429-Y495 HydrophobicContact CD1-CE1 4.21Å; L429-Y495 HydrophobicContact CD1-CE2 4.05Å; L429-Y495 HydrophobicContact CD1-CG 4.14Å; L429-Y495 HydrophobicContact CD2-CD2 4.06Å; L429-Y495 HydrophobicContact CD2-CE2 4.13Å; L429-Y495 HydrophobicContact CG-CE2 4.48Å; L429-F518 HydrophobicContact CB-CE2 4.39Å; L429-F518 HydrophobicContact CD1-CD2 3.99Å; L429-F518 HydrophobicContact CD1-CE2 3.95Å
430R78.1Confident77.6Confident63 Ų6342.3 Ų42.324%0.23819%0.194CC..  trans-142.8119.3-175.8-61.7-174.4-179.1-169.7-6.8110.2N228 A365 K428 Y489N228-R430 VanDerWaalsContact CG-CZ 3.49Å; N228-R430 PolarHBondContact OD1-NH1 3.17Å; A365-R430 VanDerWaalsContact CA-CZ 3.5Å; A365-R430 VanDerWaalsContact CA-NH2 3.29Å; A365-R430 PolarHBondContact O-NH2 2.97Å; A365-R430 VanDerWaalsContact O-NH2 3.07Å; K428-R430 PolarHBondContact O-N 2.77Å; R430-Y489 PolarHBondContact N-OH 2.62Å; R430-Y489 WeakPolarHBondContact O-CE2 3.31Å; R430-Y489 VanDerWaalsContact O-CZ 3.24Å; R430-Y489 PolarHBondContact O-OH 3.31Å
431H85.8Confident78.5Confident59 Ų5940.8 Ų40.827%0.27319%0.186SC..  trans-159.1148.1179.6-171.9-91.8000109.3N433 L434 Y489H431-N433 VanDerWaalsContact C-N 3.28Å; H431-N433 PolarHBondContact CE1-OD1 2.97Å; H431-N433 VanDerWaalsContact CE1-OD1 3.24Å; H431-N433 PolarHBondContact ND1-N 3.18Å; H431-N433 VanDerWaalsContact ND1-N 3.1Å; H431-N433 PolarHBondContact O-N 3.37Å; H431-L434 HydrophobicContact CB-CB 4.12Å; H431-L434 HydrophobicContact CB-CD1 3.92Å; H431-L434 HydrophobicContact CB-CG 3.84Å; H431-L434 PolarHBondContact O-N 3.34Å; H431-L434 VanDerWaalsContact O-N 3.07Å; H431-Y489 HydrophobicContact CB-CD1 3.88Å; H431-Y489 HydrophobicContact CB-CD2 4.26Å; H431-Y489 HydrophobicContact CB-CE1 4.24Å; H431-Y489 HydrophobicContact CB-CG 3.86Å; H431-Y489 AromaticContact CD2-CD2 3.84Å; H431-Y489 AromaticContact CD2-CG 3.79Å; H431-Y489 AromaticContact CG-CG 3.97Å
432E87.3Confident79.2Confident136 Ų13635.7 Ų35.764%0.63616%0.164SC*.THydrogen-bonded Turntrans-58.2-40.7-177.4-173.5173.9173.600112.3L434 K514E432-L434 VanDerWaalsContact C-N 3.35Å; E432-L434 PolarHBondContact O-N 2.84Å; E432-K514 WeakPolarHBondContact O-CD 2.88Å; E432-K514 WeakPolarHBondContact O-CE 3.42Å
433N94.4Very high79.5Confident4 Ų441.1 Ų41.12%0.02119%0.187CC..THydrogen-bonded Turntrans-91.719.2177.8-48.596000114.7H431 D482 V513 K514 V515H431-N433 VanDerWaalsContact C-N 3.28Å; H431-N433 PolarHBondContact CE1-OD1 2.97Å; H431-N433 VanDerWaalsContact CE1-OD1 3.24Å; H431-N433 PolarHBondContact ND1-N 3.18Å; H431-N433 VanDerWaalsContact ND1-N 3.1Å; H431-N433 PolarHBondContact O-N 3.37Å; N433-D482 WeakPolarHBondContact CB-O 3.13Å; N433-D482 VanDerWaalsContact CG-O 3.26Å; N433-D482 WeakPolarHBondContact ND2-CA 3.21Å; N433-D482 VanDerWaalsContact ND2-CB 3.31Å; N433-D482 WeakPolarHBondContact ND2-CB 3.36Å; N433-D482 PolarHBondContact ND2-OD1 3.47Å; N433-V513 PolarHBondContact ND2-O 3.3Å; N433-K514 CarbonylContact O-C 3.54Å; N433-K514 WeakPolarHBondContact O-CA 3.49Å; N433-V515 PolarHBondContact O-N 3.25Å
434L91.4Very high79.6Confident2 Ų245.6 Ų45.61%0.0121%0.207CC..BIsolated β-bridgetrans-116.7140.1168.5-67-175.4000109.7H431 E432 Q436 Y489 L490 V515 F518H431-L434 HydrophobicContact CB-CB 4.12Å; H431-L434 HydrophobicContact CB-CD1 3.92Å; H431-L434 HydrophobicContact CB-CG 3.84Å; H431-L434 PolarHBondContact O-N 3.34Å; H431-L434 VanDerWaalsContact O-N 3.07Å; E432-L434 VanDerWaalsContact C-N 3.35Å; E432-L434 PolarHBondContact O-N 2.84Å; L434-Q436 PolarHBondContact O-N 3.44Å; L434-Y489 HydrophobicContact CD1-CD1 3.51Å; L434-Y489 HydrophobicContact CD1-CE1 3.91Å; L434-L490 HydrophobicContact CD1-CD2 3.65Å; L434-L490 HydrophobicContact CD1-CG 3.94Å; L434-L490 HydrophobicContact CD2-CD1 4.03Å; L434-L490 HydrophobicContact CD2-CD2 4.5Å; L434-L490 HydrophobicContact CD2-CG 4.1Å; L434-V515 HydrophobicContact CD2-CB 3.75Å; L434-V515 HydrophobicContact CD2-CG2 4.39Å; L434-F518 HydrophobicContact CB-CE1 4.19Å; L434-F518 HydrophobicContact CD2-CD1 4.46Å; L434-F518 HydrophobicContact CD2-CE1 4.47Å
435V90.4Very high79.9Confident2 Ų247.4 Ų47.41%0.01221%0.212CC..PPolyproline II helixtrans-67.1119.9174.4171.40000109.5L437 T451 E452 L454 L506 K514 V515 F518V435-L437 PolarHBondContact O-N 2.89Å; V435-T451 HydrophobicContact CG1-CG2 4.24Å; V435-E452 HydrophobicContact CG1-CG 3.87Å; V435-L454 HydrophobicContact CG2-CD1 4.31Å; V435-L454 HydrophobicContact CG2-CD2 4.48Å; V435-L506 HydrophobicContact CG2-CB 4.32Å; V435-L506 HydrophobicContact CG2-CD1 4.01Å; V435-L506 HydrophobicContact CG2-CG 4.37Å; V435-K514 HydrophobicContact CG2-CB 3.7Å; V435-V515 PolarHBondContact N-O 2.93Å; V435-F518 WeakPolarHBondContact O-CE1 3.23Å; V435-F518 WeakPolarHBondContact O-CZ 3.33Å
436Q85.3Confident80.3Confident14 Ų1446.1 Ų46.17%0.06521%0.208CC..PPolyproline II helixtrans-68.9122.9-178.7-172.15862.200111.3L434 Y438 T451 E452L434-Q436 PolarHBondContact O-N 3.44Å; Q436-Y438 HydrophobicContact CB-CE1 4.25Å; Q436-Y438 HydrophobicContact CG-CD1 3.97Å; Q436-Y438 HydrophobicContact CG-CE1 3.86Å; Q436-T451 VanDerWaalsContact O-CA 3.26Å; Q436-T451 WeakPolarHBondContact O-CA 3.4Å; Q436-T451 VanDerWaalsContact O-CB 3.32Å; Q436-T451 WeakPolarHBondContact O-CB 3.35Å; Q436-E452 HydrophobicContact CB-CG 4.2Å; Q436-E452 WeakPolarHBondContact CB-OE1 3.36Å; Q436-E452 PolarHBondContact N-OE1 3.47Å; Q436-E452 PolarHBondContact O-N 3.02Å
437L84.4Confident80.9Confident4 Ų446 Ų462%0.02121%0.207CC..EExtended strand (participates in β ladder)trans-78.8120.5166.517962.5000109.2M426 M427 V435 I449 V450 T451M426-L437 HydrophobicContact CB-CD2 3.69Å; M426-L437 HydrophobicContact CE-CD2 4.08Å; M426-L437 HydrophobicContact SD-CD2 4.32Å; M427-L437 HydrophobicContact CB-CD2 4.5Å; M427-L437 HydrophobicContact CG-CD2 3.53Å; M427-L437 HydrophobicContact CG-CG 3.84Å; V435-L437 PolarHBondContact O-N 2.89Å; L437-I449 HydrophobicContact CD1-CG2 3.29Å; L437-V450 WeakPolarHBondContact CD1-O 3.46Å; L437-T451 HydrophobicContact CD1-CG2 4.07Å
438Y81Confident81.7Confident30 Ų3045.4 Ų45.412%0.11820%0.204CC..EExtended strand (participates in β ladder)trans-87-38.9176.2-64.9-33.9000112.1L367 V404 M427 Q436 V450 E452L367-Y438 WeakPolarHBondContact CG-O 3.36Å; V404-Y438 HydrophobicContact CG1-CD2 3.91Å; V404-Y438 HydrophobicContact CG1-CE2 4.01Å; M427-Y438 WeakPolarHBondContact CE-O 3.06Å; Q436-Y438 HydrophobicContact CB-CE1 4.25Å; Q436-Y438 HydrophobicContact CG-CD1 3.97Å; Q436-Y438 HydrophobicContact CG-CE1 3.86Å; Y438-V450 WeakPolarHBondContact CB-O 2.98Å; Y438-V450 HydrophobicContact CD2-CG1 4.49Å; Y438-V450 PolarHBondContact N-O 2.84Å; Y438-E452 HydrophobicContact CE1-CB 4.43Å; Y438-E452 VanDerWaalsContact CE2-CA 3.47Å; Y438-E452 HydrophobicContact CE2-CB 4.03Å; Y438-E452 VanDerWaalsContact OH-CB 3.31Å; Y438-E452 WeakPolarHBondContact OH-CB 3.33Å
439G82.3Confident82.4Confident0 Ų039.1 Ų39.10%018%0.177CC..EExtended strand (participates in β ladder)trans171.8-174.3177.600000112.7W372 V450W372-G439 WeakPolarHBondContact O-CA 3.19Å; G439-V450 PolarHBondContact N-O 3.46Å; G439-V450 PolarHBondContact O-N 3.43Å
440V83.8Confident83Confident1 Ų138.8 Ų38.81%0.00618%0.175CC..EExtended strand (participates in β ladder)trans-130.1153.4179.6-64.60000111.5W372 E373 I374 F419 A423 T442 Y448 I449W372-V440 HydrophobicContact CE3-CG2 3.66Å; W372-V440 HydrophobicContact CZ3-CG2 3.75Å; W372-V440 PolarHBondContact O-N 3.49Å; E373-V440 CarbonylContact C-O 3.53Å; E373-V440 VanDerWaalsContact CA-O 3.28Å; E373-V440 WeakPolarHBondContact CA-O 3.23Å; I374-V440 PolarHBondContact N-O 3.04Å; F419-V440 HydrophobicContact CE1-CB 4.1Å; F419-V440 HydrophobicContact CE1-CG1 3.93Å; F419-V440 HydrophobicContact CE1-CG2 4.49Å; F419-V440 HydrophobicContact CZ-CG1 4Å; A423-V440 HydrophobicContact CB-CG1 3.71Å; A423-V440 HydrophobicContact CB-CG2 4.31Å; V440-T442 HydrophobicContact CB-CG2 4.47Å; V440-T442 HydrophobicContact CG2-CG2 4.07Å; V440-Y448 CarbonylContact C-O 3.48Å; V440-Y448 WeakPolarHBondContact CA-O 3.17Å; V440-Y448 WeakPolarHBondContact CB-O 3.44Å; V440-I449 HydrophobicContact CG1-CG1 4.38Å
441C85.3Confident83.5Confident0 Ų037 Ų370%017%0.171CC..EExtended strand (participates in β ladder)trans-110.6106.4170-56.50000109.2I374 P376 L379 I447 Y448I374-C441 PolarHBondContact O-SG 3.44Å; P376-C441 HydrophobicContact CG-CB 4.12Å; L379-C441 VanDerWaalsContact CD1-SG 3.56Å; C441-I447 WeakPolarHBondContact O-CA 3.45Å; C441-I447 WeakPolarHBondContact O-CG2 3.37Å; C441-Y448 HydrophobicContact CB-CD2 3.62Å; C441-Y448 HydrophobicContact CB-CG 4.07Å; C441-Y448 PolarHBondContact N-O 2.91Å; C441-Y448 PolarHBondContact O-N 3Å; C441-Y448 VanDerWaalsContact O-N 3.08Å
442T77Confident83.6Confident23 Ų2334.9 Ų34.914%0.14116%0.161CC..  trans-109.5-17.8-177.243.10000113.8E373 F419 I420 V440 Q444 I447E373-T442 PolarHBondContact OE1-OG1 3.36Å; F419-T442 HydrophobicContact CD1-CG2 4.17Å; F419-T442 HydrophobicContact CE1-CG2 4.03Å; I420-T442 HydrophobicContact CD1-CG2 4.12Å; I420-T442 HydrophobicContact CG1-CG2 3.75Å; V440-T442 HydrophobicContact CB-CG2 4.47Å; V440-T442 HydrophobicContact CG2-CG2 4.07Å; T442-Q444 VanDerWaalsContact C-N 3.27Å; T442-Q444 PolarHBondContact O-N 3.04Å; T442-I447 HydrophobicContact CG2-CG2 4.12Å
443K71.6Confident83.8Confident162 Ų16231.2 Ų31.270%0.70414%0.143SC*.SBendtrans-68.3-17.1177.2-85.3158.4-172.1160.20115.6E373E373-K443 VanDerWaalsContact CD-CE 3.42Å; E373-K443 WeakPolarHBondContact OE1-CD 3.29Å; E373-K443 WeakPolarHBondContact OE1-CE 3.45Å; E373-K443 VanDerWaalsContact OE1-CG 3.24Å; E373-K443 WeakPolarHBondContact OE1-CG 3.27Å; E373-K443 PolarHBondContact OE1-N 2.91Å; E373-K443 IonicContact OE1-NZ 3.75Å; E373-K443 WeakPolarHBondContact OE2-CE 3.47Å; E373-K443 IonicContact OE2-NZ 2.68Å; E373-K443 PolarHBondContact OE2-NZ 3.33Å
444Q71.7Confident83.7Confident98 Ų9831.6 Ų31.646%0.45815%0.145SC..SBendtrans-131.4144.1-178.4-178.3175-6.500110.1P376 T442 P446P376-Q444 VanDerWaalsContact CB-OE1 3.26Å; P376-Q444 HydrophobicContact CG-CB 3.82Å; T442-Q444 VanDerWaalsContact C-N 3.27Å; T442-Q444 PolarHBondContact O-N 3.04Å; Q444-P446 CarbonylContact O-C 3.55Å
445R74.5Confident83.6Confident129 Ų12934.4 Ų34.449%0.48717%0.169SC..SBendtrans-93144.9169.6-66.1-158.1-171.2-72.4-8.1111.9E411 E416E411-R445 WeakPolarHBondContact OE1-CD 3.32Å; E416-R445 IonicContact OE1-CZ 3.85Å; E416-R445 IonicContact OE1-NH1 3.9Å; E416-R445 PolarHBondContact OE1-NH1 3.39Å; E416-R445 IonicContact OE1-NH2 3.8Å; E416-R445 PolarHBondContact OE1-NH2 2.98Å; E416-R445 IonicContact OE2-NH2 3.06Å; E416-R445 PolarHBondContact OE2-NH2 3.24Å; E416-R445 VanDerWaalsContact OE2-NH2 3.15Å
446P76Confident83.6Confident40 Ų4037.5 Ų37.526%0.2619%0.185SC..SBendcis-70.3156.4-8.826.6-28.9000112.1M408 I409 Q444 Y448M408-P446 HydrophobicContact CE-CG 3.66Å; I409-P446 WeakPolarHBondContact O-CB 3.49Å; Q444-P446 CarbonylContact O-C 3.55Å; P446-Y448 HydrophobicContact CG-CE1 3.93Å; P446-Y448 WeakPolarHBondContact O-CD1 2.88Å; P446-Y448 WeakPolarHBondContact O-CE1 3.47Å
447I81.6Confident84Confident14 Ų1438.3 Ų38.37%0.07220%0.198CC..PPolyproline II helixtrans-65.3141.9179.7-64.9173.8000109.7I409 E416 F419 C441 T442I409-I447 HydrophobicContact CB-CB 4.42Å; I409-I447 PolarHBondContact N-O 3.3Å; E416-I447 HydrophobicContact CG-CD1 4.16Å; F419-I447 HydrophobicContact CD1-CD1 4.41Å; F419-I447 HydrophobicContact CD1-CG2 3.97Å; F419-I447 HydrophobicContact CE1-CG2 3.29Å; F419-I447 HydrophobicContact CE2-CG2 4.31Å; F419-I447 HydrophobicContact CZ-CG2 3.47Å; F419-I447 VanDerWaalsContact CZ-CG2 3.47Å; C441-I447 WeakPolarHBondContact O-CA 3.45Å; C441-I447 WeakPolarHBondContact O-CG2 3.37Å; T442-I447 HydrophobicContact CG2-CG2 4.12Å
448Y86.3Confident84.4Confident15 Ų1539.6 Ų39.66%0.05921%0.207CC..EExtended strand (participates in β ladder)trans-113.1140.3176.6-49.6-43.8000112.7P376 L379 F381 I406 K407 M408 V440 C441 P446P376-Y448 HydrophobicContact CB-CE2 4.36Å; L379-Y448 HydrophobicContact CD1-CD2 4.29Å; F381-Y448 HydrophobicContact CZ-CD2 4.33Å; F381-Y448 HydrophobicContact CZ-CE1 4.44Å; F381-Y448 AromaticContact CZ-CE2 3.87Å; F381-Y448 HydrophobicContact CZ-CE2 3.87Å; F381-Y448 AromaticContact CZ-CZ 3.95Å; I406-Y448 HydrophobicContact CG2-CD1 4.32Å; I406-Y448 HydrophobicContact CG2-CG 4.07Å; K407-Y448 CarbonylContact O-C 3.49Å; K407-Y448 WeakPolarHBondContact O-CA 3.31Å; M408-Y448 HydrophobicContact CB-CD1 4.16Å; M408-Y448 HydrophobicContact CB-CE1 4.15Å; M408-Y448 HydrophobicContact CE-CE1 3.79Å; M408-Y448 HydrophobicContact CG-CD1 3.83Å; M408-Y448 HydrophobicContact CG-CE1 3.69Å; M408-Y448 HydrophobicContact SD-CE1 4.47Å; V440-Y448 CarbonylContact C-O 3.48Å; V440-Y448 WeakPolarHBondContact CA-O 3.17Å; V440-Y448 WeakPolarHBondContact CB-O 3.44Å; C441-Y448 HydrophobicContact CB-CD2 3.62Å; C441-Y448 HydrophobicContact CB-CG 4.07Å; C441-Y448 PolarHBondContact N-O 2.91Å; C441-Y448 PolarHBondContact O-N 3Å; C441-Y448 VanDerWaalsContact O-N 3.08Å; P446-Y448 HydrophobicContact CG-CE1 3.93Å; P446-Y448 WeakPolarHBondContact O-CD1 2.88Å; P446-Y448 WeakPolarHBondContact O-CE1 3.47Å
449I86.2Confident85.2Confident19 Ų1938.1 Ų38.110%0.09720%0.201CC..EExtended strand (participates in β ladder)trans-106.8127.9162.1-58177.3000107I406 K407 I409 F419 L437 V440 T451I406-I449 WeakPolarHBondContact CA-O 3.47Å; K407-I449 HydrophobicContact CB-CB 4.27Å; K407-I449 PolarHBondContact N-O 3.17Å; K407-I449 PolarHBondContact O-N 3.29Å; I409-I449 HydrophobicContact CD1-CD1 3.84Å; I409-I449 HydrophobicContact CD1-CG1 4.27Å; I409-I449 HydrophobicContact CG1-CD1 4.28Å; I409-I449 HydrophobicContact CG1-CG1 4.25Å; F419-I449 HydrophobicContact CE2-CD1 3.85Å; F419-I449 HydrophobicContact CE2-CG1 3.92Å; F419-I449 HydrophobicContact CZ-CD1 4.04Å; F419-I449 HydrophobicContact CZ-CG1 3.58Å; L437-I449 HydrophobicContact CD1-CG2 3.29Å; V440-I449 HydrophobicContact CG1-CG1 4.38Å; I449-T451 HydrophobicContact CG2-CG2 3.99Å
450V87.9Confident85.9Confident0 Ų039.9 Ų39.90%021%0.21CC..EExtended strand (participates in β ladder)trans-113.3119.7-179.8-172.40000109.3I374 L379 V404 A405 L437 Y438 G439I374-V450 HydrophobicContact CD1-CB 3.49Å; I374-V450 VanDerWaalsContact CD1-CB 3.49Å; I374-V450 HydrophobicContact CD1-CG1 3.91Å; I374-V450 HydrophobicContact CD1-CG2 3.52Å; L379-V450 HydrophobicContact CD1-CG2 3.81Å; L379-V450 HydrophobicContact CD2-CG1 4.31Å; L379-V450 HydrophobicContact CD2-CG2 4.22Å; V404-V450 HydrophobicContact CB-CG1 3.73Å; V404-V450 HydrophobicContact CG1-CG1 3.86Å; V404-V450 HydrophobicContact CG2-CG1 4.07Å; A405-V450 WeakPolarHBondContact O-CA 3.48Å; L437-V450 WeakPolarHBondContact CD1-O 3.46Å; Y438-V450 WeakPolarHBondContact CB-O 2.98Å; Y438-V450 HydrophobicContact CD2-CG1 4.49Å; Y438-V450 PolarHBondContact N-O 2.84Å; G439-V450 PolarHBondContact N-O 3.46Å; G439-V450 PolarHBondContact O-N 3.43Å
451T89.7Confident86.4Confident24 Ų2442.9 Ų42.915%0.14723%0.229CC..EExtended strand (participates in β ladder)trans-125.1171-179.266.40000111.3A405 V435 Q436 L437 I449A405-T451 PolarHBondContact N-O 3.21Å; A405-T451 PolarHBondContact O-N 3.47Å; V435-T451 HydrophobicContact CG1-CG2 4.24Å; Q436-T451 VanDerWaalsContact O-CA 3.26Å; Q436-T451 WeakPolarHBondContact O-CA 3.4Å; Q436-T451 VanDerWaalsContact O-CB 3.32Å; Q436-T451 WeakPolarHBondContact O-CB 3.35Å; L437-T451 HydrophobicContact CD1-CG2 4.07Å; I449-T451 HydrophobicContact CG2-CG2 3.99Å
452E87.7Confident86.9Confident16 Ų1644.6 Ų44.68%0.07524%0.235CC..EExtended strand (participates in β ladder)trans-55144.6166.461.1174.5122.600111.5V435 Q436 Y438 L454 K514V435-E452 HydrophobicContact CG1-CG 3.87Å; Q436-E452 HydrophobicContact CB-CG 4.2Å; Q436-E452 WeakPolarHBondContact CB-OE1 3.36Å; Q436-E452 PolarHBondContact N-OE1 3.47Å; Q436-E452 PolarHBondContact O-N 3.02Å; Y438-E452 HydrophobicContact CE1-CB 4.43Å; Y438-E452 VanDerWaalsContact CE2-CA 3.47Å; Y438-E452 HydrophobicContact CE2-CB 4.03Å; Y438-E452 VanDerWaalsContact OH-CB 3.31Å; Y438-E452 WeakPolarHBondContact OH-CB 3.33Å; E452-L454 HydrophobicContact CB-CD1 4.36Å; E452-L454 HydrophobicContact CG-CD1 3.54Å; E452-K514 VanDerWaalsContact CD-NZ 3.31Å; E452-K514 IonicContact OE1-NZ 3.85Å; E452-K514 PolarHBondContact OE1-NZ 2.97Å; E452-K514 IonicContact OE2-NZ 3.95Å; E452-K514 PolarHBondContact OE2-NZ 3.48Å
453F91.6Very high87.8Confident59 Ų5943.8 Ų43.826%0.25923%0.23SC..  trans-91.9123.7176.2171.6-112000110.9L385 Y395 D403 A455L385-F453 HydrophobicContact CD1-CD2 4.01Å; L385-F453 HydrophobicContact CD1-CE2 3.8Å; L385-F453 HydrophobicContact CD2-CE2 4.11Å; Y395-F453 HydrophobicContact CD2-CD1 4.02Å; Y395-F453 AromaticContact CD2-CD2 3.74Å; Y395-F453 HydrophobicContact CD2-CD2 3.74Å; Y395-F453 HydrophobicContact CD2-CE1 4.09Å; Y395-F453 AromaticContact CD2-CE2 3.83Å; Y395-F453 HydrophobicContact CD2-CE2 3.83Å; Y395-F453 AromaticContact CD2-CG 3.84Å; Y395-F453 HydrophobicContact CD2-CG 3.84Å; Y395-F453 AromaticContact CD2-CZ 4Å; Y395-F453 HydrophobicContact CD2-CZ 4Å; Y395-F453 AromaticContact CE2-CD1 3.98Å; Y395-F453 HydrophobicContact CE2-CD1 3.98Å; Y395-F453 HydrophobicContact CE2-CE1 4.1Å; Y395-F453 HydrophobicContact CE2-CG 4.19Å; Y395-F453 HydrophobicContact CE2-CZ 4.43Å; Y395-F453 HydrophobicContact CG-CE2 4.34Å; D403-F453 HydrophobicContact CB-CB 4.23Å; D403-F453 HydrophobicContact CB-CD1 4.15Å; F453-A455 HydrophobicContact CE1-CB 4.02Å; F453-A455 HydrophobicContact CZ-CB 4.38Å
454L92Very high88.8Confident11 Ų1141.8 Ų41.86%0.05822%0.221CC..  trans-107.9111.7177.3-83.678.9000110.4V435 E452 N456 G457 L506 V507 D508 K514V435-L454 HydrophobicContact CG2-CD1 4.31Å; V435-L454 HydrophobicContact CG2-CD2 4.48Å; E452-L454 HydrophobicContact CB-CD1 4.36Å; E452-L454 HydrophobicContact CG-CD1 3.54Å; L454-N456 VanDerWaalsContact C-N 3.32Å; L454-N456 PolarHBondContact O-N 3.23Å; L454-G457 PolarHBondContact O-N 3.06Å; L454-L506 HydrophobicContact CB-CB 3.96Å; L454-L506 HydrophobicContact CB-CD1 4.26Å; L454-L506 HydrophobicContact CD1-CD1 4.45Å; L454-L506 HydrophobicContact CD2-CB 3.47Å; L454-L506 VanDerWaalsContact CD2-CB 3.47Å; L454-L506 HydrophobicContact CG-CB 4.21Å; L454-V507 WeakPolarHBondContact CB-O 3.37Å; L454-D508 HydrophobicContact CD2-CB 4.12Å; L454-D508 HydrophobicContact CG-CB 4.28Å; L454-K514 HydrophobicContact CD2-CB 4.02Å; L454-K514 HydrophobicContact CD2-CD 4.02Å; L454-K514 HydrophobicContact CD2-CG 4.01Å
455A88.4Confident89.8Confident62 Ų6244.5 Ų44.551%0.51223%0.234SC..THydrogen-bonded Turntrans-66.3-27.1-166.700000114.8F453 G457F453-A455 HydrophobicContact CE1-CB 4.02Å; F453-A455 HydrophobicContact CZ-CB 4.38Å; A455-G457 VanDerWaalsContact C-N 3.31Å
456N92Very high90.1Very high66 Ų6639.9 Ų39.935%0.35323%0.226SC..THydrogen-bonded Turntrans-89.24.6-178.4-71.6-38.4000113.3L454 Y462 V507 D508L454-N456 VanDerWaalsContact C-N 3.32Å; L454-N456 PolarHBondContact O-N 3.23Å; N456-Y462 HydrophobicContact CB-CD2 3.84Å; N456-Y462 HydrophobicContact CB-CE2 4.01Å; N456-V507 HydrophobicContact CB-CB 3.86Å; N456-V507 HydrophobicContact CB-CG1 4.02Å; N456-V507 WeakPolarHBondContact CB-O 3.43Å; N456-V507 PolarHBondContact N-O 3.14Å; N456-D508 PolarHBondContact ND2-O 2.83Å
457G92.4Very high90.6Very high32 Ų3239.9 Ų39.933%0.3322%0.224SC..  trans69-154.9175.200000112.9L454 A455 L506 V507L454-G457 PolarHBondContact O-N 3.06Å; A455-G457 VanDerWaalsContact C-N 3.31Å; G457-L506 CarbonylContact O-C 3.54Å; G457-L506 VanDerWaalsContact O-CA 3.31Å; G457-L506 WeakPolarHBondContact O-CA 3.45Å; G457-V507 PolarHBondContact O-N 3Å
458C94.1Very high90.4Very high30 Ų3049.1 Ų49.120%0.20326%0.263CS..BIsolated β-bridgetrans-80.1148.2-178.471.80000112.8L460 T461 Y462 R503 C505 L506C458-L460 PolarHBondContact O-N 3.16Å; C458-T461 PolarHBondContact O-N 2.82Å; C458-T461 VanDerWaalsContact O-N 3.12Å; C458-T461 PolarHBondContact SG-OG1 3.37Å; C458-T461 VanDerWaalsContact SG-OG1 3.41Å; C458-Y462 WeakPolarHBondContact O-CB 3.37Å; C458-Y462 PolarHBondContact O-N 3.37Å; C458-R503 WeakPolarHBondContact CB-O 3.21Å; C458-C505 CarbonylContact C-O 3.54Å; C458-C505 WeakPolarHBondContact CA-O 3.33Å; C458-C505 WeakPolarHBondContact CB-O 3.42Å; C458-L506 HydrophobicContact CB-CD2 3.9Å
459L97Very high90.3Very high0 Ų056.3 Ų56.30%030%0.298CS..Hα-helixtrans-57.1-37.3-176.9177.764.5000111.8T461 Y462 L463 M479 A502 C505 V507 V513 V568L459-T461 PolarHBondContact O-N 2.87Å; L459-Y462 HydrophobicContact CD1-CD1 4.39Å; L459-Y462 PolarHBondContact O-N 3.28Å; L459-L463 HydrophobicContact CD1-CD1 4.21Å; L459-L463 HydrophobicContact CD1-CD2 4.43Å; L459-L463 HydrophobicContact CD1-CG 4Å; L459-L463 HydrophobicContact CG-CD1 3.93Å; L459-L463 HydrophobicContact CG-CG 4.23Å; L459-L463 WeakPolarHBondContact O-CB 3.39Å; L459-L463 WeakPolarHBondContact O-CG 3.35Å; L459-L463 PolarHBondContact O-N 3.29Å; L459-M479 HydrophobicContact CD1-SD 3.84Å; L459-A502 WeakPolarHBondContact CB-O 3.46Å; L459-A502 HydrophobicContact CD2-CB 4.35Å; L459-A502 HydrophobicContact CG-CB 4.4Å; L459-A502 PolarHBondContact N-O 3.22Å; L459-C505 HydrophobicContact CB-CB 3.88Å; L459-C505 HydrophobicContact CD2-CB 4.07Å; L459-C505 PolarHBondContact N-O 2.97Å; L459-V507 HydrophobicContact CB-CG2 4.07Å; L459-V507 HydrophobicContact CD1-CG2 3.9Å; L459-V513 HydrophobicContact CD1-CG2 4.08Å; L459-V513 HydrophobicContact CD2-CG1 4.07Å; L459-V568 HydrophobicContact CD2-CG2 3.98Å
460L96.1Very high90.2Very high36 Ų3664 Ų6419%0.18833%0.333CS..Hα-helixtrans-58.3-48.1176.5179.262.1000112.8C458 K464 A502 R503C458-L460 PolarHBondContact O-N 3.16Å; L460-K464 WeakPolarHBondContact O-CG 3.34Å; L460-K464 PolarHBondContact O-N 3.34Å; L460-A502 HydrophobicContact CB-CB 4.06Å; L460-A502 PolarHBondContact N-O 3.42Å; L460-R503 HydrophobicContact CB-CB 4.48Å; L460-R503 HydrophobicContact CD2-CB 4.17Å
461T94.4Very high90.4Very high65 Ų6564.7 Ų64.740%0.39934%0.338SS..Hα-helixtrans-71.4-38.4177.6-57.30000110.4C458 L459 L463 K464 E465C458-T461 PolarHBondContact O-N 2.82Å; C458-T461 VanDerWaalsContact O-N 3.12Å; C458-T461 PolarHBondContact SG-OG1 3.37Å; C458-T461 VanDerWaalsContact SG-OG1 3.41Å; L459-T461 PolarHBondContact O-N 2.87Å; T461-L463 VanDerWaalsContact C-N 3.35Å; T461-L463 PolarHBondContact O-N 3.13Å; T461-K464 PolarHBondContact O-N 3.25Å; T461-E465 HydrophobicContact CG2-CB 4.49Å; T461-E465 PolarHBondContact O-N 2.79Å
462Y95.7Very high90.5Very high36 Ų3667.1 Ų67.114%0.14135%0.352CS..Iπ-helixtrans-58.8-43.7176.8-174.3-105.6000112.5N456 C458 L459 K464 G466 L467 M479 V507N456-Y462 HydrophobicContact CB-CD2 3.84Å; N456-Y462 HydrophobicContact CB-CE2 4.01Å; C458-Y462 WeakPolarHBondContact O-CB 3.37Å; C458-Y462 PolarHBondContact O-N 3.37Å; L459-Y462 HydrophobicContact CD1-CD1 4.39Å; L459-Y462 PolarHBondContact O-N 3.28Å; Y462-K464 VanDerWaalsContact C-N 3.33Å; Y462-K464 PolarHBondContact O-N 2.69Å; Y462-G466 CarbonylContact O-C 3.6Å; Y462-G466 VanDerWaalsContact O-CA 3.27Å; Y462-G466 WeakPolarHBondContact O-CA 3.34Å; Y462-G466 PolarHBondContact O-N 3.04Å; Y462-L467 HydrophobicContact CD1-CD2 4.32Å; Y462-L467 HydrophobicContact CE1-CD2 3.62Å; Y462-L467 HydrophobicContact CE1-CG 4.25Å; Y462-L467 PolarHBondContact O-N 3.39Å; Y462-L467 VanDerWaalsContact O-N 3.14Å; Y462-M479 HydrophobicContact CD1-CE 4.46Å; Y462-M479 HydrophobicContact CE1-CE 3.9Å; Y462-V507 HydrophobicContact CD1-CB 4.44Å; Y462-V507 HydrophobicContact CD1-CG1 4.12Å; Y462-V507 HydrophobicContact CD1-CG2 3.91Å; Y462-V507 HydrophobicContact CD2-CB 4.49Å; Y462-V507 HydrophobicContact CD2-CG1 4.34Å; Y462-V507 HydrophobicContact CE1-CG1 4.03Å; Y462-V507 HydrophobicContact CE2-CG1 4.27Å; Y462-V507 HydrophobicContact CG-CB 4.26Å; Y462-V507 HydrophobicContact CG-CG1 4.27Å; Y462-V507 HydrophobicContact CG-CG2 3.92Å
463L96.1Very high90.6Very high6 Ų669.2 Ų69.23%0.03137%0.366CS..Iπ-helixtrans-63.1-35.9176.3-72.7165000113L459 T461 L467 L476 M479 V568 L571L459-L463 HydrophobicContact CD1-CD1 4.21Å; L459-L463 HydrophobicContact CD1-CD2 4.43Å; L459-L463 HydrophobicContact CD1-CG 4Å; L459-L463 HydrophobicContact CG-CD1 3.93Å; L459-L463 HydrophobicContact CG-CG 4.23Å; L459-L463 WeakPolarHBondContact O-CB 3.39Å; L459-L463 WeakPolarHBondContact O-CG 3.35Å; L459-L463 PolarHBondContact O-N 3.29Å; T461-L463 VanDerWaalsContact C-N 3.35Å; T461-L463 PolarHBondContact O-N 3.13Å; L463-L467 HydrophobicContact CD2-CD1 4.37Å; L463-L476 HydrophobicContact CD2-CD2 4.05Å; L463-M479 HydrophobicContact CD2-SD 4.13Å; L463-V568 HydrophobicContact CD1-CB 4.49Å; L463-V568 HydrophobicContact CD1-CG2 4.18Å; L463-V568 HydrophobicContact CD2-CG1 4.42Å; L463-L571 HydrophobicContact CD2-CD2 4.43Å
464K93.9Very high90.7Very high120 Ų12067.7 Ų67.752%0.52236%0.362SS..Iπ-helixtrans-81.8-39.5-177.7-71.9-180178.5-179.40113.3L460 T461 Y462 G572L460-K464 WeakPolarHBondContact O-CG 3.34Å; L460-K464 PolarHBondContact O-N 3.34Å; T461-K464 PolarHBondContact O-N 3.25Å; Y462-K464 VanDerWaalsContact C-N 3.33Å; Y462-K464 PolarHBondContact O-N 2.69Å; K464-G572 WeakPolarHBondContact CE-O 3.39Å; K464-G572 PolarHBondContact NZ-O 3.43Å
465E91.6Very high90.7Very high155 Ų15571.2 Ų71.272%0.72438%0.378SS*.Iπ-helixtrans-132.2-25.6-162.9-62.7171.6-163.800113.2T461T461-E465 HydrophobicContact CG2-CB 4.49Å; T461-E465 PolarHBondContact O-N 2.79Å
466G81.8Confident91.1Very high31 Ų3168.3 Ų68.332%0.3235%0.354SS..Iπ-helixtrans-85.5-22.8-172.400000115Y462 K468Y462-G466 CarbonylContact O-C 3.6Å; Y462-G466 VanDerWaalsContact O-CA 3.27Å; Y462-G466 WeakPolarHBondContact O-CA 3.34Å; Y462-G466 PolarHBondContact O-N 3.04Å; G466-K468 PolarHBondContact O-N 3.28Å
467L85.1Confident91.4Very high41 Ų4165.2 Ų65.222%0.21534%0.337CS..  trans-73.5111.2179.5-68.7171.6000111Y462 L463 Q469 P471 M479Y462-L467 HydrophobicContact CD1-CD2 4.32Å; Y462-L467 HydrophobicContact CE1-CD2 3.62Å; Y462-L467 HydrophobicContact CE1-CG 4.25Å; Y462-L467 PolarHBondContact O-N 3.39Å; Y462-L467 VanDerWaalsContact O-N 3.14Å; L463-L467 HydrophobicContact CD2-CD1 4.37Å; L467-Q469 PolarHBondContact O-N 3.39Å; L467-P471 HydrophobicContact CD1-CB 3.94Å; L467-P471 HydrophobicContact CD1-CG 3.69Å; L467-M479 HydrophobicContact CD2-CE 4.3Å
468K78.4Confident91.5Very high207 Ų20767.2 Ų67.290%0.934%0.338SS*.SBendtrans-69.2-21.1179.9-62.9-176.8-177.1175.90113.9G466G466-K468 PolarHBondContact O-N 3.28Å
469Q83.4Confident91.7Very high166 Ų16666.4 Ų66.478%0.77633%0.331SS*.SBendtrans-138.5161.3179.7-63.2-178.313.600108.7L467L467-Q469 PolarHBondContact O-N 3.39Å
470H85.6Confident91.8Very high180 Ų18066.4 Ų66.483%0.83333%0.331SS*.PPolyproline II helixtrans-58.8124.6172.5-79.3-67.3000109.9
471P90.6Very high91.8Very high16 Ų1666.5 Ų66.510%0.10433%0.33CS..PPolyproline II helixtrans-70143.7-176.930.5-35.7000110L467 L476 L571L467-P471 HydrophobicContact CD1-CB 3.94Å; L467-P471 HydrophobicContact CD1-CG 3.69Å; P471-L476 HydrophobicContact CB-CD2 3.9Å; P471-L476 HydrophobicContact CB-CG 4.12Å; P471-L476 HydrophobicContact CG-CD1 4.35Å; P471-L476 HydrophobicContact CG-CD2 3.89Å; P471-L476 HydrophobicContact CG-CG 4.23Å; P471-L571 HydrophobicContact CG-CD2 3.68Å
472T91.8Very high92Very high74 Ų7464.5 Ų64.545%0.45432%0.317SS..PPolyproline II helixtrans-73.6157.1169.370.80000110V474 Q475 L476T472-V474 PolarHBondContact O-N 3.15Å; T472-Q475 PolarHBondContact O-N 3.41Å; T472-Q475 WeakPolarHBondContact OG1-CG 3.28Å; T472-Q475 PolarHBondContact OG1-N 3.17Å; T472-Q475 VanDerWaalsContact OG1-N 3.12Å; T472-L476 WeakPolarHBondContact O-CG 3.41Å; T472-L476 PolarHBondContact O-N 2.78Å; T472-L476 VanDerWaalsContact O-N 3.16Å
473T91.5Very high92.1Very high60 Ų6062.8 Ų62.837%0.36831%0.31SS..Hα-helixtrans-61.4-30.8174.953.90000112.2L476 L477 Y569 L599T473-L476 PolarHBondContact O-N 3.19Å; T473-L477 PolarHBondContact O-N 3.48Å; T473-L477 VanDerWaalsContact O-N 3.07Å; T473-Y569 PolarHBondContact O-OH 3.26Å; T473-L599 WeakPolarHBondContact CG2-O 3.09Å
474V92.2Very high92.2Very high27 Ų2762.5 Ų62.516%0.16431%0.309CS..Hα-helixtrans-66.4-46.8175.4178.20000110.5T472 L476 L477 E478 L633 L636 Q637T472-V474 PolarHBondContact O-N 3.15Å; V474-L476 VanDerWaalsContact C-N 3.29Å; V474-L476 PolarHBondContact O-N 3.45Å; V474-L477 CarbonylContact O-C 3.44Å; V474-L477 WeakPolarHBondContact O-CA 3.49Å; V474-L477 PolarHBondContact O-N 3.4Å; V474-E478 HydrophobicContact CG1-CG 4.43Å; V474-E478 WeakPolarHBondContact O-CG 3.47Å; V474-E478 PolarHBondContact O-N 2.94Å; V474-L633 HydrophobicContact CG1-CD2 3.95Å; V474-L636 HydrophobicContact CG2-CB 4.15Å; V474-Q637 HydrophobicContact CG1-CG 4.04Å
475Q93.4Very high92.3Very high86 Ų8659.2 Ų59.240%0.40230%0.295SS..Hα-helixtrans-59-39.6176.4-75.8170.7-20.800112.5T472 L477 E478 M479T472-Q475 PolarHBondContact O-N 3.41Å; T472-Q475 WeakPolarHBondContact OG1-CG 3.28Å; T472-Q475 PolarHBondContact OG1-N 3.17Å; T472-Q475 VanDerWaalsContact OG1-N 3.12Å; Q475-L477 VanDerWaalsContact C-N 3.33Å; Q475-E478 PolarHBondContact O-N 3.45Å; Q475-M479 WeakPolarHBondContact O-CG 3.37Å; Q475-M479 PolarHBondContact O-N 3.48Å; Q475-M479 VanDerWaalsContact O-N 3.13Å
476L96.8Very high92.5Very high1 Ų151.8 Ų51.81%0.00526%0.261CS..Hα-helixtrans-65.6-37.9175.2-64.8180000111.8L463 P471 T472 T473 V474 M479 C480 V568 Y569 L571 L599L463-L476 HydrophobicContact CD2-CD2 4.05Å; P471-L476 HydrophobicContact CB-CD2 3.9Å; P471-L476 HydrophobicContact CB-CG 4.12Å; P471-L476 HydrophobicContact CG-CD1 4.35Å; P471-L476 HydrophobicContact CG-CD2 3.89Å; P471-L476 HydrophobicContact CG-CG 4.23Å; T472-L476 WeakPolarHBondContact O-CG 3.41Å; T472-L476 PolarHBondContact O-N 2.78Å; T472-L476 VanDerWaalsContact O-N 3.16Å; T473-L476 PolarHBondContact O-N 3.19Å; V474-L476 VanDerWaalsContact C-N 3.29Å; V474-L476 PolarHBondContact O-N 3.45Å; L476-M479 HydrophobicContact CD2-SD 4.41Å; L476-M479 PolarHBondContact O-N 2.93Å; L476-C480 PolarHBondContact O-N 3.12Å; L476-C480 PolarHBondContact O-SG 3.28Å; L476-C480 VanDerWaalsContact O-SG 3.35Å; L476-V568 HydrophobicContact CB-CG1 3.88Å; L476-V568 HydrophobicContact CD2-CG1 3.82Å; L476-V568 HydrophobicContact CG-CG1 4.38Å; L476-V568 WeakPolarHBondContact O-CG1 3.27Å; L476-Y569 HydrophobicContact CB-CE1 4.31Å; L476-Y569 HydrophobicContact CB-CE2 4.23Å; L476-Y569 HydrophobicContact CD1-CD1 4.23Å; L476-Y569 HydrophobicContact CD1-CE1 4.43Å; L476-L571 HydrophobicContact CD1-CD2 4.23Å; L476-L571 HydrophobicContact CD2-CD2 4.01Å; L476-L599 HydrophobicContact CD1-CB 4.38Å; L476-L599 HydrophobicContact CD1-CD1 3.95Å
477L96.8Very high93.2Very high0 Ų050.4 Ų50.40%025%0.246CC..Hα-helixtrans-71.4-34.5176.8-165.760.7000112.2T473 V474 Q475 C480 K481 M565 Y569 V604 V629 L632 L633 L636T473-L477 PolarHBondContact O-N 3.48Å; T473-L477 VanDerWaalsContact O-N 3.07Å; V474-L477 CarbonylContact O-C 3.44Å; V474-L477 WeakPolarHBondContact O-CA 3.49Å; V474-L477 PolarHBondContact O-N 3.4Å; Q475-L477 VanDerWaalsContact C-N 3.33Å; L477-C480 WeakPolarHBondContact O-CB 3.32Å; L477-C480 PolarHBondContact O-N 3.13Å; L477-K481 WeakPolarHBondContact O-CB 3.41Å; L477-K481 PolarHBondContact O-N 3.33Å; L477-M565 HydrophobicContact CD1-CE 4.42Å; L477-Y569 WeakPolarHBondContact CB-OH 3.39Å; L477-V604 HydrophobicContact CD1-CG2 4.38Å; L477-V629 HydrophobicContact CD1-CG1 3.78Å; L477-V629 HydrophobicContact CG-CG1 3.96Å; L477-L632 HydrophobicContact CD2-CB 4.15Å; L477-L632 HydrophobicContact CD2-CD2 3.99Å; L477-L632 HydrophobicContact CD2-CG 3.8Å; L477-L633 HydrophobicContact CB-CD2 3.75Å; L477-L633 HydrophobicContact CB-CG 4.25Å; L477-L633 HydrophobicContact CD2-CB 4.49Å; L477-L633 HydrophobicContact CD2-CD2 3.83Å; L477-L633 HydrophobicContact CD2-CG 3.7Å; L477-L633 HydrophobicContact CG-CD1 4.46Å; L477-L633 HydrophobicContact CG-CD2 3.83Å; L477-L633 HydrophobicContact CG-CG 3.77Å; L477-L636 HydrophobicContact CD2-CD1 3.88Å
478E96.4Very high93.7Very high75 Ų7548.9 Ų48.935%0.3524%0.239SC..Hα-helixtrans-59.9-43.8171.8-72.2170.516100111.1V474 Q475 C480 K481 D482 L633V474-E478 HydrophobicContact CG1-CG 4.43Å; V474-E478 WeakPolarHBondContact O-CG 3.47Å; V474-E478 PolarHBondContact O-N 2.94Å; Q475-E478 PolarHBondContact O-N 3.45Å; E478-C480 VanDerWaalsContact C-N 3.33Å; E478-C480 PolarHBondContact O-N 3.48Å; E478-K481 WeakPolarHBondContact O-CB 3.36Å; E478-K481 PolarHBondContact O-N 2.87Å; E478-D482 PolarHBondContact O-N 3.18Å; E478-L633 HydrophobicContact CG-CD1 4.33Å; E478-L633 HydrophobicContact CG-CD2 3.79Å
479M97.8Very high94.4Very high13 Ų1341.6 Ų41.66%0.06421%0.206CC..Hα-helixtrans-60.4-40.6173.9-66.7175-166.500112.6L459 Y462 L463 L467 Q475 L476 V483 V513L459-M479 HydrophobicContact CD1-SD 3.84Å; Y462-M479 HydrophobicContact CD1-CE 4.46Å; Y462-M479 HydrophobicContact CE1-CE 3.9Å; L463-M479 HydrophobicContact CD2-SD 4.13Å; L467-M479 HydrophobicContact CD2-CE 4.3Å; Q475-M479 WeakPolarHBondContact O-CG 3.37Å; Q475-M479 PolarHBondContact O-N 3.48Å; Q475-M479 VanDerWaalsContact O-N 3.13Å; L476-M479 HydrophobicContact CD2-SD 4.41Å; L476-M479 PolarHBondContact O-N 2.93Å; M479-V483 WeakPolarHBondContact O-CG2 3.5Å; M479-V483 PolarHBondContact O-N 2.97Å; M479-V513 HydrophobicContact CB-CG2 3.77Å; M479-V513 HydrophobicContact CG-CG2 3.75Å
480C98.3Very high94.8Very high0 Ų033.7 Ų33.70%017%0.169CC..Hα-helixtrans-66.6-39.6175.7-65.60000111.7L476 L477 E478 V483 S484 Y561 M565L476-C480 PolarHBondContact O-N 3.12Å; L476-C480 PolarHBondContact O-SG 3.28Å; L476-C480 VanDerWaalsContact O-SG 3.35Å; L477-C480 WeakPolarHBondContact O-CB 3.32Å; L477-C480 PolarHBondContact O-N 3.13Å; E478-C480 VanDerWaalsContact C-N 3.33Å; E478-C480 PolarHBondContact O-N 3.48Å; C480-V483 PolarHBondContact O-N 2.9Å; C480-S484 PolarHBondContact O-N 3.2Å; C480-S484 PolarHBondContact O-OG 3Å; C480-Y561 PolarHBondContact O-OH 3.28Å; C480-M565 HydrophobicContact CB-CE 4.27Å; C480-M565 HydrophobicContact CB-CG 4.27Å
481K97.4Very high95.1Very high38 Ų3826.6 Ų26.617%0.16514%0.137CC..Hα-helixtrans-58.6-51.9177.6-173.9-138173-124.70110.8L477 E478 V483 S484 E485 V629 L633L477-K481 WeakPolarHBondContact O-CB 3.41Å; L477-K481 PolarHBondContact O-N 3.33Å; E478-K481 WeakPolarHBondContact O-CB 3.36Å; E478-K481 PolarHBondContact O-N 2.87Å; K481-V483 VanDerWaalsContact C-N 3.3Å; K481-V483 PolarHBondContact O-N 2.89Å; K481-S484 WeakPolarHBondContact CA-OG 3.28Å; K481-S484 PolarHBondContact O-N 3.43Å; K481-S484 PolarHBondContact O-OG 3.31Å; K481-E485 WeakPolarHBondContact CE-OE1 3.02Å; K481-E485 WeakPolarHBondContact CE-OE2 3.43Å; K481-E485 IonicContact NZ-OE1 2.72Å; K481-E485 PolarHBondContact NZ-OE1 2.99Å; K481-E485 IonicContact NZ-OE2 3.7Å; K481-E485 PolarHBondContact NZ-OE2 3.48Å; K481-E485 PolarHBondContact O-N 3.49Å; K481-V629 HydrophobicContact CB-CG1 3.62Å; K481-V629 HydrophobicContact CG-CG1 4.16Å; K481-L633 HydrophobicContact CB-CD1 3.74Å; K481-L633 HydrophobicContact CD-CD1 3.77Å; K481-L633 HydrophobicContact CG-CD1 3.85Å
482D96.9Very high95.1Very high22 Ų2229 Ų2912%0.11816%0.158CC..Hα-helixtrans-51.7-48.6176.5-75.1-6.1000111.8N433 E478 S484 E485 G486 T512 V513N433-D482 WeakPolarHBondContact CB-O 3.13Å; N433-D482 VanDerWaalsContact CG-O 3.26Å; N433-D482 WeakPolarHBondContact ND2-CA 3.21Å; N433-D482 VanDerWaalsContact ND2-CB 3.31Å; N433-D482 WeakPolarHBondContact ND2-CB 3.36Å; N433-D482 PolarHBondContact ND2-OD1 3.47Å; E478-D482 PolarHBondContact O-N 3.18Å; D482-S484 PolarHBondContact O-N 3.04Å; D482-E485 PolarHBondContact O-N 3.33Å; D482-G486 PolarHBondContact O-N 2.95Å; D482-G486 VanDerWaalsContact O-N 3.13Å; D482-T512 WeakPolarHBondContact OD2-CA 3.49Å; D482-V513 HydrophobicContact CB-CB 3.88Å; D482-V513 WeakPolarHBondContact CB-O 3.24Å; D482-V513 PolarHBondContact OD2-N 3.25Å
483V98.4Very high94.7Very high0 Ų029.7 Ų29.70%016%0.156CC..Hα-helixtrans-62.9-42.9177.71750000111.5M479 C480 K481 E485 G486 M487 L500 V513 V515 Y561 L564M479-V483 WeakPolarHBondContact O-CG2 3.5Å; M479-V483 PolarHBondContact O-N 2.97Å; C480-V483 PolarHBondContact O-N 2.9Å; K481-V483 VanDerWaalsContact C-N 3.3Å; K481-V483 PolarHBondContact O-N 2.89Å; V483-E485 PolarHBondContact O-N 3.41Å; V483-G486 PolarHBondContact O-N 2.98Å; V483-M487 HydrophobicContact CG1-CG 4.3Å; V483-M487 WeakPolarHBondContact O-CB 3.48Å; V483-M487 WeakPolarHBondContact O-CG 3.36Å; V483-M487 PolarHBondContact O-N 3.43Å; V483-L500 HydrophobicContact CG1-CD1 4.13Å; V483-V513 HydrophobicContact CG2-CB 4.29Å; V483-V513 HydrophobicContact CG2-CG1 3.54Å; V483-V515 HydrophobicContact CB-CG2 4.44Å; V483-V515 HydrophobicContact CG1-CG2 4.01Å; V483-V515 HydrophobicContact CG2-CG2 4.49Å; V483-Y561 HydrophobicContact CB-CE2 4.23Å; V483-Y561 HydrophobicContact CG1-CD2 3.88Å; V483-Y561 HydrophobicContact CG1-CE2 3.99Å; V483-L564 HydrophobicContact CB-CD2 4.5Å; V483-L564 HydrophobicContact CG1-CD1 3.95Å; V483-L564 HydrophobicContact CG1-CD2 4.25Å; V483-L564 HydrophobicContact CG2-CD2 4.32Å
484S97.9Very high94.2Very high0 Ų030.2 Ų30.20%016%0.155CC..Hα-helixtrans-64.7-36.9179.969.50000112.9C480 K481 D482 M487 A488 A626C480-S484 PolarHBondContact O-N 3.2Å; C480-S484 PolarHBondContact O-OG 3Å; K481-S484 WeakPolarHBondContact CA-OG 3.28Å; K481-S484 PolarHBondContact O-N 3.43Å; K481-S484 PolarHBondContact O-OG 3.31Å; D482-S484 PolarHBondContact O-N 3.04Å; S484-M487 PolarHBondContact O-N 3.43Å; S484-A488 VanDerWaalsContact O-CB 3.3Å; S484-A488 WeakPolarHBondContact O-CB 3.44Å; S484-A488 PolarHBondContact O-N 3.38Å; S484-A626 WeakPolarHBondContact OG-CA 3.39Å
485E96.3Very high93.8Very high51 Ų5129.4 Ų29.424%0.23815%0.149CC..Hα-helixtrans-67.7-44.1176.3-70.1177.5144.400111.2K481 D482 V483 M487 A488 Y489 A626K481-E485 WeakPolarHBondContact CE-OE1 3.02Å; K481-E485 WeakPolarHBondContact CE-OE2 3.43Å; K481-E485 IonicContact NZ-OE1 2.72Å; K481-E485 PolarHBondContact NZ-OE1 2.99Å; K481-E485 IonicContact NZ-OE2 3.7Å; K481-E485 PolarHBondContact NZ-OE2 3.48Å; K481-E485 PolarHBondContact O-N 3.49Å; D482-E485 PolarHBondContact O-N 3.33Å; V483-E485 PolarHBondContact O-N 3.41Å; E485-M487 VanDerWaalsContact C-N 3.34Å; E485-M487 PolarHBondContact O-N 3.18Å; E485-A488 PolarHBondContact O-N 3.29Å; E485-Y489 PolarHBondContact O-N 3.27Å; E485-Y489 VanDerWaalsContact O-N 3.09Å; E485-A626 HydrophobicContact CG-CB 4.36Å
486G94.9Very high93.3Very high0 Ų025.4 Ų25.40%013%0.13CC..Hα-helixtrans-60.8-41.3174.100000112.9D482 V483 Y489 L490D482-G486 PolarHBondContact O-N 2.95Å; D482-G486 VanDerWaalsContact O-N 3.13Å; V483-G486 PolarHBondContact O-N 2.98Å; G486-Y489 PolarHBondContact O-N 3.29Å; G486-L490 PolarHBondContact O-N 3.19Å; G486-L490 VanDerWaalsContact O-N 3.17Å
487M96.9Very high93Very high2 Ų225.5 Ų25.51%0.0113%0.13CC..Hα-helixtrans-73.6-33.7178-71.1-59.6-55.300113.3V483 S484 E485 Y489 L490 E491 H497 L500 V515 D557 F622V483-M487 HydrophobicContact CG1-CG 4.3Å; V483-M487 WeakPolarHBondContact O-CB 3.48Å; V483-M487 WeakPolarHBondContact O-CG 3.36Å; V483-M487 PolarHBondContact O-N 3.43Å; S484-M487 PolarHBondContact O-N 3.43Å; E485-M487 VanDerWaalsContact C-N 3.34Å; E485-M487 PolarHBondContact O-N 3.18Å; M487-Y489 VanDerWaalsContact C-N 3.29Å; M487-Y489 PolarHBondContact O-N 3.39Å; M487-L490 HydrophobicContact CE-CD1 4.48Å; M487-L490 PolarHBondContact O-N 3Å; M487-L490 HydrophobicContact SD-CD1 3.89Å; M487-E491 WeakPolarHBondContact O-CB 3.44Å; M487-E491 PolarHBondContact O-N 3.43Å; M487-H497 HydrophobicContact CE-CB 3.83Å; M487-H497 HydrophobicContact SD-CB 4.23Å; M487-L500 HydrophobicContact CE-CD2 4.13Å; M487-L500 HydrophobicContact CG-CD1 4.29Å; M487-L500 HydrophobicContact CG-CD2 3.87Å; M487-L500 HydrophobicContact SD-CD1 3.96Å; M487-L500 HydrophobicContact SD-CD2 3.99Å; M487-L500 HydrophobicContact SD-CG 4.48Å; M487-V515 HydrophobicContact CG-CG2 4.43Å; M487-V515 HydrophobicContact SD-CG1 4.2Å; M487-D557 HydrophobicContact CE-CB 3.81Å; M487-F622 HydrophobicContact CB-CB 4.48Å; M487-F622 HydrophobicContact CB-CD1 3.4Å; M487-F622 HydrophobicContact CB-CD2 3.93Å; M487-F622 HydrophobicContact CB-CE1 3.36Å; M487-F622 HydrophobicContact CB-CE2 3.89Å; M487-F622 HydrophobicContact CB-CG 3.69Å; M487-F622 HydrophobicContact CB-CZ 3.62Å; M487-F622 HydrophobicContact CE-CD2 4.41Å; M487-F622 HydrophobicContact CE-CE2 3.58Å; M487-F622 HydrophobicContact CE-CZ 3.65Å; M487-F622 HydrophobicContact CG-CD1 4.36Å; M487-F622 HydrophobicContact CG-CE1 3.84Å; M487-F622 HydrophobicContact CG-CE2 4.47Å; M487-F622 HydrophobicContact CG-CZ 3.91Å
488A96.6Very high92.5Very high9 Ų928 Ų287%0.07414%0.14CC..Hα-helixtrans-61.7-40.2172.600000111.2S484 E485 E491 A492 F622S484-A488 VanDerWaalsContact O-CB 3.3Å; S484-A488 WeakPolarHBondContact O-CB 3.44Å; S484-A488 PolarHBondContact O-N 3.38Å; E485-A488 PolarHBondContact O-N 3.29Å; A488-E491 PolarHBondContact O-N 3.39Å; A488-A492 WeakPolarHBondContact O-CB 3.49Å; A488-A492 PolarHBondContact O-N 3.39Å; A488-F622 VanDerWaalsContact CA-CB 3.5Å; A488-F622 HydrophobicContact CB-CB 3.89Å
489Y93.4Very high92.1Very high53 Ų5326.2 Ų26.221%0.20813%0.133CC..Hα-helixtrans-62-46.1172.2177.4-92000112L429 R430 H431 L434 E485 G486 M487 E491 A492 Q493L429-Y489 HydrophobicContact CB-CE1 4.18Å; L429-Y489 HydrophobicContact CD2-CE1 4.07Å; R430-Y489 PolarHBondContact N-OH 2.62Å; R430-Y489 WeakPolarHBondContact O-CE2 3.31Å; R430-Y489 VanDerWaalsContact O-CZ 3.24Å; R430-Y489 PolarHBondContact O-OH 3.31Å; H431-Y489 HydrophobicContact CB-CD1 3.88Å; H431-Y489 HydrophobicContact CB-CD2 4.26Å; H431-Y489 HydrophobicContact CB-CE1 4.24Å; H431-Y489 HydrophobicContact CB-CG 3.86Å; H431-Y489 AromaticContact CD2-CD2 3.84Å; H431-Y489 AromaticContact CD2-CG 3.79Å; H431-Y489 AromaticContact CG-CG 3.97Å; L434-Y489 HydrophobicContact CD1-CD1 3.51Å; L434-Y489 HydrophobicContact CD1-CE1 3.91Å; E485-Y489 PolarHBondContact O-N 3.27Å; E485-Y489 VanDerWaalsContact O-N 3.09Å; G486-Y489 PolarHBondContact O-N 3.29Å; M487-Y489 VanDerWaalsContact C-N 3.29Å; M487-Y489 PolarHBondContact O-N 3.39Å; Y489-E491 PolarHBondContact O-N 3.37Å; Y489-A492 PolarHBondContact O-N 3.13Å; Y489-Q493 HydrophobicContact CD1-CG 4.23Å; Y489-Q493 HydrophobicContact CE1-CG 3.83Å; Y489-Q493 HydrophobicContact CE2-CG 4.22Å; Y489-Q493 WeakPolarHBondContact O-CG 3.41Å; Y489-Q493 PolarHBondContact O-N 3.37Å
490L90.6Very high92Very high0 Ų025.6 Ų25.60%013%0.13CC..Hα-helixtrans-61.4-42.9176.9-69.8-179.2000112.4L429 L434 G486 M487 A492 Q493 Q494 Y495 F518L429-L490 HydrophobicContact CD1-CD2 3.9Å; L434-L490 HydrophobicContact CD1-CD2 3.65Å; L434-L490 HydrophobicContact CD1-CG 3.94Å; L434-L490 HydrophobicContact CD2-CD1 4.03Å; L434-L490 HydrophobicContact CD2-CD2 4.5Å; L434-L490 HydrophobicContact CD2-CG 4.1Å; G486-L490 PolarHBondContact O-N 3.19Å; G486-L490 VanDerWaalsContact O-N 3.17Å; M487-L490 HydrophobicContact CE-CD1 4.48Å; M487-L490 PolarHBondContact O-N 3Å; M487-L490 HydrophobicContact SD-CD1 3.89Å; L490-A492 PolarHBondContact O-N 3.31Å; L490-Q493 CarbonylContact O-C 3.55Å; L490-Q493 PolarHBondContact O-N 2.87Å; L490-Q493 VanDerWaalsContact O-N 3.13Å; L490-Q494 PolarHBondContact O-N 2.85Å; L490-Q494 VanDerWaalsContact O-N 3.12Å; L490-Y495 PolarHBondContact O-N 3.21Å; L490-F518 HydrophobicContact CD1-CB 4.21Å
491E92.1Very high91.9Very high31 Ų3125.6 Ų25.615%0.14513%0.13CC..Hα-helixtrans-58.6-46.2175.2-175-180-116.500110.8M487 A488 Y489 Q493 Q494 F622M487-E491 WeakPolarHBondContact O-CB 3.44Å; M487-E491 PolarHBondContact O-N 3.43Å; A488-E491 PolarHBondContact O-N 3.39Å; Y489-E491 PolarHBondContact O-N 3.37Å; E491-Q493 VanDerWaalsContact C-N 3.26Å; E491-Q493 PolarHBondContact O-N 3.25Å; E491-Q494 PolarHBondContact O-N 2.99Å; E491-Q494 PolarHBondContact O-NE2 3.15Å; E491-F622 HydrophobicContact CB-CB 4.46Å; E491-F622 HydrophobicContact CB-CD2 4.28Å; E491-F622 PolarHBondContact OE1-N 2.9Å; E491-F622 PolarHBondContact OE2-N 2.74Å
492A89.8Confident91.9Very high68 Ų6823.8 Ų23.856%0.56212%0.122SC*.Hα-helixtrans-62.4-32.3176.100000113A488 Y489 L490 Q494A488-A492 WeakPolarHBondContact O-CB 3.49Å; A488-A492 PolarHBondContact O-N 3.39Å; Y489-A492 PolarHBondContact O-N 3.13Å; L490-A492 PolarHBondContact O-N 3.31Å; A492-Q494 VanDerWaalsContact C-N 3.27Å; A492-Q494 PolarHBondContact O-N 3.41Å
493Q84.3Confident91.7Very high87 Ų8726 Ų2641%0.40713%0.129SC..THydrogen-bonded Turntrans-84.15.2174.4-60.8-52.3-62.500113.7L429 Y489 L490 E491 Y495L429-Q493 HydrophobicContact CD2-CB 3.82Å; L429-Q493 HydrophobicContact CD2-CG 3.82Å; Y489-Q493 HydrophobicContact CD1-CG 4.23Å; Y489-Q493 HydrophobicContact CE1-CG 3.83Å; Y489-Q493 HydrophobicContact CE2-CG 4.22Å; Y489-Q493 WeakPolarHBondContact O-CG 3.41Å; Y489-Q493 PolarHBondContact O-N 3.37Å; L490-Q493 CarbonylContact O-C 3.55Å; L490-Q493 PolarHBondContact O-N 2.87Å; L490-Q493 VanDerWaalsContact O-N 3.13Å; E491-Q493 VanDerWaalsContact C-N 3.26Å; E491-Q493 PolarHBondContact O-N 3.25Å; Q493-Y495 VanDerWaalsContact C-N 3.32Å; Q493-Y495 HydrophobicContact CB-CD2 4.17Å; Q493-Y495 WeakPolarHBondContact O-CD2 3.42Å; Q493-Y495 PolarHBondContact O-N 3.46Å
494Q81.3Confident91.5Very high72 Ų7226.7 Ų26.734%0.33613%0.132SC..THydrogen-bonded Turntrans60.340.3-179.3-55.1-65.4-67.600113L490 E491 A492 Y523 V524L490-Q494 PolarHBondContact O-N 2.85Å; L490-Q494 VanDerWaalsContact O-N 3.12Å; E491-Q494 PolarHBondContact O-N 2.99Å; E491-Q494 PolarHBondContact O-NE2 3.15Å; A492-Q494 VanDerWaalsContact C-N 3.27Å; A492-Q494 PolarHBondContact O-N 3.41Å; Q494-Y523 HydrophobicContact CB-CE2 4.15Å; Q494-V524 PolarHBondContact O-N 3.05Å
495Y82.6Confident91.4Very high10 Ų1026.7 Ų26.74%0.03913%0.132CC..EExtended strand (participates in β ladder)trans-109.3127.7177.3-96.8-90.4000111.4I425 L429 L490 Q493 Y523I425-Y495 VanDerWaalsContact CB-OH 3.23Å; I425-Y495 WeakPolarHBondContact CB-OH 3.4Å; I425-Y495 HydrophobicContact CG2-CE2 3.93Å; I425-Y495 WeakPolarHBondContact CG2-OH 3.32Å; L429-Y495 HydrophobicContact CD1-CD1 4.21Å; L429-Y495 HydrophobicContact CD1-CD2 4.06Å; L429-Y495 HydrophobicContact CD1-CE1 4.21Å; L429-Y495 HydrophobicContact CD1-CE2 4.05Å; L429-Y495 HydrophobicContact CD1-CG 4.14Å; L429-Y495 HydrophobicContact CD2-CD2 4.06Å; L429-Y495 HydrophobicContact CD2-CE2 4.13Å; L429-Y495 HydrophobicContact CG-CE2 4.48Å; L490-Y495 PolarHBondContact O-N 3.21Å; Q493-Y495 VanDerWaalsContact C-N 3.32Å; Q493-Y495 HydrophobicContact CB-CD2 4.17Å; Q493-Y495 WeakPolarHBondContact O-CD2 3.42Å; Q493-Y495 PolarHBondContact O-N 3.46Å; Y495-Y523 HydrophobicContact CD2-CD2 4.05Å; Y495-Y523 AromaticContact CE2-CD2 3.68Å; Y495-Y523 HydrophobicContact CE2-CD2 3.68Å; Y495-Y523 HydrophobicContact CE2-CG 4.39Å
496I84.8Confident91.4Very high1 Ų125.8 Ų25.81%0.00513%0.129CC..EExtended strand (participates in β ladder)trans-103.9120.4175.3-51.8166.6000108.9R498 S521 R522 V524 F552 D557I496-R498 HydrophobicContact CB-CG 4.26Å; I496-R498 HydrophobicContact CG2-CG 3.66Å; I496-S521 WeakPolarHBondContact O-CA 3.22Å; I496-S521 WeakPolarHBondContact O-CB 3.27Å; I496-S521 PolarHBondContact O-OG 3.01Å; I496-R522 PolarHBondContact N-O 3.49Å; I496-R522 PolarHBondContact O-N 2.97Å; I496-V524 HydrophobicContact CD1-CB 3.89Å; I496-V524 HydrophobicContact CD1-CG1 4.31Å; I496-V524 HydrophobicContact CD1-CG2 3.8Å; I496-F552 HydrophobicContact CG2-CB 4.41Å; I496-D557 WeakPolarHBondContact CA-OD2 3.32Å; I496-D557 VanDerWaalsContact CG2-OD2 3.29Å; I496-D557 WeakPolarHBondContact CG2-OD2 3.41Å
497H89.4Confident91.4Very high3 Ų325.8 Ų25.81%0.01413%0.129CC..  trans-69.3-44.9-177.5-169.9-41.4000113.5M487 D499 L500 V515 T516 S521 D557M487-H497 HydrophobicContact CE-CB 3.83Å; M487-H497 HydrophobicContact SD-CB 4.23Å; H497-D499 PolarHBondContact ND1-N 3.24Å; H497-D499 PolarHBondContact O-N 2.89Å; H497-L500 PolarHBondContact ND1-N 2.85Å; H497-V515 WeakPolarHBondContact CD2-CG1 3.3Å; H497-V515 VanDerWaalsContact NE2-CG1 3.3Å; H497-V515 WeakPolarHBondContact NE2-CG1 3.34Å; H497-T516 PolarHBondContact NE2-O 3.5Å; H497-T516 VanDerWaalsContact NE2-O 3.09Å; H497-S521 WeakPolarHBondContact CA-OG 3.21Å; H497-D557 PolarHBondContact N-OD2 3.46Å
498R86.1Confident91Very high53 Ų5326.9 Ų26.920%0.214%0.135CC..SBendtrans68.8-9.5175.7-51.4167.859-147.5-7.5117.1I496 L520 F552 D557I496-R498 HydrophobicContact CB-CG 4.26Å; I496-R498 HydrophobicContact CG2-CG 3.66Å; R498-L520 PolarHBondContact NH1-O 2.83Å; R498-F552 HydrophobicContact CB-CD1 3.82Å; R498-F552 HydrophobicContact CB-CE1 4.08Å; R498-F552 HydrophobicContact CG-CB 4.21Å; R498-F552 HydrophobicContact CG-CD1 3.84Å; R498-F552 HydrophobicContact CG-CG 4.15Å; R498-D557 WeakPolarHBondContact CA-OD1 2.99Å; R498-D557 PolarHBondContact N-OD1 2.63Å
499D88.4Confident90.5Very high38 Ų3830.2 Ų30.220%0.20316%0.162CC..  trans-146.237.8179.2-166.623.1000111.2H497 A501 R503 N504 P538H497-D499 PolarHBondContact ND1-N 3.24Å; H497-D499 PolarHBondContact O-N 2.89Å; D499-A501 PolarHBondContact O-N 3.16Å; D499-R503 IonicContact OD1-CZ 3.97Å; D499-R503 IonicContact OD1-NH2 2.97Å; D499-R503 PolarHBondContact OD1-NH2 3.17Å; D499-N504 PolarHBondContact O-ND2 3.49Å; D499-N504 PolarHBondContact OD2-ND2 3.43Å; D499-P538 WeakPolarHBondContact OD1-CB 2.86Å; D499-P538 VanDerWaalsContact OD1-CG 3.23Å; D499-P538 WeakPolarHBondContact OD1-CG 3.43Å
500L95.4Very high90Very high0 Ų032.9 Ų32.90%018%0.18CC..  trans-66.2123.4175.6-17865000110V483 M487 H497 V515 A560 Y561 L564 F622V483-L500 HydrophobicContact CG1-CD1 4.13Å; M487-L500 HydrophobicContact CE-CD2 4.13Å; M487-L500 HydrophobicContact CG-CD1 4.29Å; M487-L500 HydrophobicContact CG-CD2 3.87Å; M487-L500 HydrophobicContact SD-CD1 3.96Å; M487-L500 HydrophobicContact SD-CD2 3.99Å; M487-L500 HydrophobicContact SD-CG 4.48Å; H497-L500 PolarHBondContact ND1-N 2.85Å; L500-V515 HydrophobicContact CD1-CG1 4.02Å; L500-A560 HydrophobicContact CB-CB 4.05Å; L500-Y561 HydrophobicContact CD2-CD2 4.4Å; L500-L564 HydrophobicContact CD1-CD1 3.9Å; L500-L564 HydrophobicContact CG-CD1 3.99Å; L500-F622 HydrophobicContact CD2-CZ 4.2Å
501A95.9Very high89.8Confident0 Ų033.9 Ų33.90%019%0.19CC..SBendtrans-166.1161.617900000109.7D499 R503 N504 C505 W541D499-A501 PolarHBondContact O-N 3.16Å; A501-R503 HydrophobicContact CB-CG 3.98Å; A501-R503 PolarHBondContact O-N 3.01Å; A501-N504 CarbonylContact O-C 3.44Å; A501-N504 WeakPolarHBondContact O-CA 3.39Å; A501-N504 PolarHBondContact O-N 2.64Å; A501-C505 PolarHBondContact O-N 2.98Å; A501-W541 HydrophobicContact CB-CD2 4.21Å; A501-W541 HydrophobicContact CB-CG 4.2Å; A501-W541 HydrophobicContact CB-CZ2 4.39Å
502A97.1Very high89.8Confident0 Ų034 Ų340%019%0.193CC..G310 helixtrans-59.3-24.9179.700000113.7L459 L460 N504 E567L459-A502 WeakPolarHBondContact CB-O 3.46Å; L459-A502 HydrophobicContact CD2-CB 4.35Å; L459-A502 HydrophobicContact CG-CB 4.4Å; L459-A502 PolarHBondContact N-O 3.22Å; L460-A502 HydrophobicContact CB-CB 4.06Å; L460-A502 PolarHBondContact N-O 3.42Å; A502-N504 VanDerWaalsContact C-N 3.28Å; A502-N504 PolarHBondContact O-N 2.95Å; A502-E567 HydrophobicContact CB-CB 4.1Å; A502-E567 PolarHBondContact N-OE2 3.05Å
503R93.8Very high90.1Very high69 Ų6930.7 Ų30.726%0.2617%0.166SC..G310 helixtrans-69.1-23.5173.464.8174.3173.8-75.7-7.2113.9C458 L460 D499 A501 P538C458-R503 WeakPolarHBondContact CB-O 3.21Å; L460-R503 HydrophobicContact CB-CB 4.48Å; L460-R503 HydrophobicContact CD2-CB 4.17Å; D499-R503 IonicContact OD1-CZ 3.97Å; D499-R503 IonicContact OD1-NH2 2.97Å; D499-R503 PolarHBondContact OD1-NH2 3.17Å; A501-R503 HydrophobicContact CB-CG 3.98Å; A501-R503 PolarHBondContact O-N 3.01Å; R503-P538 VanDerWaalsContact NH2-CB 3.32Å
504N93.6Very high90.7Very high14 Ų1427.7 Ų27.78%0.07515%0.152CC..G310 helixtrans-107.319.7-178.5-67.8-17000111.5D499 A501 A502 T516D499-N504 PolarHBondContact O-ND2 3.49Å; D499-N504 PolarHBondContact OD2-ND2 3.43Å; A501-N504 CarbonylContact O-C 3.44Å; A501-N504 WeakPolarHBondContact O-CA 3.39Å; A501-N504 PolarHBondContact O-N 2.64Å; A502-N504 VanDerWaalsContact C-N 3.28Å; A502-N504 PolarHBondContact O-N 2.95Å; N504-T516 VanDerWaalsContact O-CG2 3.28Å; N504-T516 WeakPolarHBondContact O-CG2 3.09Å; N504-T516 PolarHBondContact O-N 3.37Å
505C96.3Very high91.3Very high0 Ų024.3 Ų24.30%014%0.136CC..EExtended strand (participates in β ladder)trans-114.5141.1163.5-590000108C458 L459 A501 V513 K514C458-C505 CarbonylContact C-O 3.54Å; C458-C505 WeakPolarHBondContact CA-O 3.33Å; C458-C505 WeakPolarHBondContact CB-O 3.42Å; L459-C505 HydrophobicContact CB-CB 3.88Å; L459-C505 HydrophobicContact CD2-CB 4.07Å; L459-C505 PolarHBondContact N-O 2.97Å; A501-C505 PolarHBondContact O-N 2.98Å; C505-V513 HydrophobicContact CB-CG1 3.7Å; C505-K514 CarbonylContact C-O 3.55Å; C505-K514 WeakPolarHBondContact CA-O 3.42Å
506L95.3Very high91.6Very high32 Ų3224.5 Ų24.517%0.16814%0.138CC..EExtended strand (participates in β ladder)trans-112.3155.5177.4-62.4-173.7000110.1V435 L454 G457 C458 V513 K514 T516V435-L506 HydrophobicContact CG2-CB 4.32Å; V435-L506 HydrophobicContact CG2-CD1 4.01Å; V435-L506 HydrophobicContact CG2-CG 4.37Å; L454-L506 HydrophobicContact CB-CB 3.96Å; L454-L506 HydrophobicContact CB-CD1 4.26Å; L454-L506 HydrophobicContact CD1-CD1 4.45Å; L454-L506 HydrophobicContact CD2-CB 3.47Å; L454-L506 VanDerWaalsContact CD2-CB 3.47Å; L454-L506 HydrophobicContact CG-CB 4.21Å; G457-L506 CarbonylContact O-C 3.54Å; G457-L506 VanDerWaalsContact O-CA 3.31Å; G457-L506 WeakPolarHBondContact O-CA 3.45Å; C458-L506 HydrophobicContact CB-CD2 3.9Å; L506-V513 CarbonylContact O-C 3.59Å; L506-V513 WeakPolarHBondContact O-CA 3.31Å; L506-K514 PolarHBondContact N-O 3.25Å; L506-K514 PolarHBondContact O-N 2.94Å; L506-T516 HydrophobicContact CD1-CG2 4.14Å; L506-T516 HydrophobicContact CD2-CG2 4.22Å; L506-T516 HydrophobicContact CG-CG2 3.71Å
507V94.9Very high91.2Very high0 Ų026.7 Ų26.70%015%0.15CC..EExtended strand (participates in β ladder)trans-117.5125.6-178.5-172.70000109.6L454 N456 G457 L459 Y462 T512 V513L454-V507 WeakPolarHBondContact CB-O 3.37Å; N456-V507 HydrophobicContact CB-CB 3.86Å; N456-V507 HydrophobicContact CB-CG1 4.02Å; N456-V507 WeakPolarHBondContact CB-O 3.43Å; N456-V507 PolarHBondContact N-O 3.14Å; G457-V507 PolarHBondContact O-N 3Å; L459-V507 HydrophobicContact CB-CG2 4.07Å; L459-V507 HydrophobicContact CD1-CG2 3.9Å; Y462-V507 HydrophobicContact CD1-CB 4.44Å; Y462-V507 HydrophobicContact CD1-CG1 4.12Å; Y462-V507 HydrophobicContact CD1-CG2 3.91Å; Y462-V507 HydrophobicContact CD2-CB 4.49Å; Y462-V507 HydrophobicContact CD2-CG1 4.34Å; Y462-V507 HydrophobicContact CE1-CG1 4.03Å; Y462-V507 HydrophobicContact CE2-CG1 4.27Å; Y462-V507 HydrophobicContact CG-CB 4.26Å; Y462-V507 HydrophobicContact CG-CG1 4.27Å; Y462-V507 HydrophobicContact CG-CG2 3.92Å; V507-T512 WeakPolarHBondContact CA-O 3.2Å; V507-V513 HydrophobicContact CG2-CG2 4.45Å
508D89.3Confident89.8Confident25 Ų2526.8 Ų26.813%0.13415%0.15CC..  trans-77.3180178.389.8-14.5000111.7L454 N456 N510 G511 T512L454-D508 HydrophobicContact CD2-CB 4.12Å; L454-D508 HydrophobicContact CG-CB 4.28Å; N456-D508 PolarHBondContact ND2-O 2.83Å; D508-N510 PolarHBondContact O-N 2.83Å; D508-N510 WeakPolarHBondContact OD1-CA 3.28Å; D508-N510 PolarHBondContact OD1-N 2.66Å; D508-N510 PolarHBondContact OD2-ND2 3.09Å; D508-G511 PolarHBondContact O-N 3.32Å; D508-G511 PolarHBondContact OD1-N 3.28Å; D508-T512 PolarHBondContact N-O 3.05Å; D508-T512 WeakPolarHBondContact OD1-CB 3.14Å; D508-T512 PolarHBondContact OD1-N 3.24Å
509A85.8Confident88.1Confident79 Ų7924.9 Ų24.965%0.65315%0.147SC*.THydrogen-bonded Turntrans-66.3-21.8-17900000114.4
510N84.1Confident86.3Confident109 Ų10925.6 Ų25.658%0.58315%0.15SC*.THydrogen-bonded Turntrans-91.7-8.5179.6-51.1-57.5000112.3R360 D508R360-N510 PolarHBondContact NH1-OD1 2.98Å; D508-N510 PolarHBondContact O-N 2.83Å; D508-N510 WeakPolarHBondContact OD1-CA 3.28Å; D508-N510 PolarHBondContact OD1-N 2.66Å; D508-N510 PolarHBondContact OD2-ND2 3.09Å
511G85.9Confident84.3Confident21 Ų2125.8 Ų25.822%0.21615%0.151CC..SBendtrans95.24-176.700000113.9D508D508-G511 PolarHBondContact O-N 3.32Å; D508-G511 PolarHBondContact OD1-N 3.28Å
512T91.6Very high82.3Confident32 Ų3230.4 Ų30.420%0.19617%0.169CC..  trans-70.9136175.5-59.30000110D482 V507 D508D482-T512 WeakPolarHBondContact OD2-CA 3.49Å; V507-T512 WeakPolarHBondContact CA-O 3.2Å; D508-T512 PolarHBondContact N-O 3.05Å; D508-T512 WeakPolarHBondContact OD1-CB 3.14Å; D508-T512 PolarHBondContact OD1-N 3.24Å
513V96.4Very high79.6Confident0 Ų036 Ų360%019%0.191CC..EExtended strand (participates in β ladder)trans-93.4134.2-179.9-174.30000110.4N433 L459 M479 D482 V483 C505 L506 V507N433-V513 PolarHBondContact ND2-O 3.3Å; L459-V513 HydrophobicContact CD1-CG2 4.08Å; L459-V513 HydrophobicContact CD2-CG1 4.07Å; M479-V513 HydrophobicContact CB-CG2 3.77Å; M479-V513 HydrophobicContact CG-CG2 3.75Å; D482-V513 HydrophobicContact CB-CB 3.88Å; D482-V513 WeakPolarHBondContact CB-O 3.24Å; D482-V513 PolarHBondContact OD2-N 3.25Å; V483-V513 HydrophobicContact CG2-CB 4.29Å; V483-V513 HydrophobicContact CG2-CG1 3.54Å; C505-V513 HydrophobicContact CB-CG1 3.7Å; L506-V513 CarbonylContact O-C 3.59Å; L506-V513 WeakPolarHBondContact O-CA 3.31Å; V507-V513 HydrophobicContact CG2-CG2 4.45Å
514K95.9Very high77.2Confident24 Ų2433.4 Ų33.410%0.10418%0.183CC..EExtended strand (participates in β ladder)trans-124.7133.7174.4-56.2-165.1-179.4-170.50111.1E432 N433 V435 E452 L454 C505 L506E432-K514 WeakPolarHBondContact O-CD 2.88Å; E432-K514 WeakPolarHBondContact O-CE 3.42Å; N433-K514 CarbonylContact O-C 3.54Å; N433-K514 WeakPolarHBondContact O-CA 3.49Å; V435-K514 HydrophobicContact CG2-CB 3.7Å; E452-K514 VanDerWaalsContact CD-NZ 3.31Å; E452-K514 IonicContact OE1-NZ 3.85Å; E452-K514 PolarHBondContact OE1-NZ 2.97Å; E452-K514 IonicContact OE2-NZ 3.95Å; E452-K514 PolarHBondContact OE2-NZ 3.48Å; L454-K514 HydrophobicContact CD2-CB 4.02Å; L454-K514 HydrophobicContact CD2-CD 4.02Å; L454-K514 HydrophobicContact CD2-CG 4.01Å; C505-K514 CarbonylContact C-O 3.55Å; C505-K514 WeakPolarHBondContact CA-O 3.42Å; L506-K514 PolarHBondContact N-O 3.25Å; L506-K514 PolarHBondContact O-N 2.94Å
515V94.9Very high74.1Confident0 Ų038.7 Ų38.70%021%0.21CC..EExtended strand (participates in β ladder)trans-75.7133.3175.6-173.20000109.5N433 L434 V435 V483 M487 H497 L500N433-V515 PolarHBondContact O-N 3.25Å; L434-V515 HydrophobicContact CD2-CB 3.75Å; L434-V515 HydrophobicContact CD2-CG2 4.39Å; V435-V515 PolarHBondContact N-O 2.93Å; V483-V515 HydrophobicContact CB-CG2 4.44Å; V483-V515 HydrophobicContact CG1-CG2 4.01Å; V483-V515 HydrophobicContact CG2-CG2 4.49Å; M487-V515 HydrophobicContact CG-CG2 4.43Å; M487-V515 HydrophobicContact SD-CG1 4.2Å; H497-V515 WeakPolarHBondContact CD2-CG1 3.3Å; H497-V515 VanDerWaalsContact NE2-CG1 3.3Å; H497-V515 WeakPolarHBondContact NE2-CG1 3.34Å; L500-V515 HydrophobicContact CD1-CG1 4.02Å
516T89.1Confident71.3Confident15 Ų1544.1 Ų44.19%0.09224%0.239CC..  trans-124.9-180-179.9-161.50000111.2H497 N504 L506 F518H497-T516 PolarHBondContact NE2-O 3.5Å; H497-T516 VanDerWaalsContact NE2-O 3.09Å; N504-T516 VanDerWaalsContact O-CG2 3.28Å; N504-T516 WeakPolarHBondContact O-CG2 3.09Å; N504-T516 PolarHBondContact O-N 3.37Å; L506-T516 HydrophobicContact CD1-CG2 4.14Å; L506-T516 HydrophobicContact CD2-CG2 4.22Å; L506-T516 HydrophobicContact CG-CG2 3.71Å; T516-F518 PolarHBondContact O-N 3.2Å
517D75.3Confident68.8Low46 Ų4644.7 Ų44.725%0.24624%0.243CC..  trans57.219.1176.2-81-0.7000114.8K407 G519K407-D517 IonicContact NZ-OD1 2.75Å; K407-D517 PolarHBondContact NZ-OD1 3.05Å; K407-D517 IonicContact NZ-OD2 3.65Å; K407-D517 PolarHBondContact NZ-OD2 3.43Å; D517-G519 PolarHBondContact O-N 2.53Å
518F60.1Low66.5Low6 Ų650.9 Ų50.93%0.02627%0.272CS..G310 helixtrans-68.44.7163.363.6-95.1000112.6M426 L429 L434 V435 L490 T516 L520 S521M426-F518 HydrophobicContact CB-CE2 4.4Å; M426-F518 HydrophobicContact CE-CD2 3.87Å; M426-F518 HydrophobicContact CE-CE2 3.76Å; M426-F518 HydrophobicContact CG-CD2 4.48Å; M426-F518 HydrophobicContact CG-CE2 4.46Å; L429-F518 HydrophobicContact CB-CE2 4.39Å; L429-F518 HydrophobicContact CD1-CD2 3.99Å; L429-F518 HydrophobicContact CD1-CE2 3.95Å; L434-F518 HydrophobicContact CB-CE1 4.19Å; L434-F518 HydrophobicContact CD2-CD1 4.46Å; L434-F518 HydrophobicContact CD2-CE1 4.47Å; V435-F518 WeakPolarHBondContact O-CE1 3.23Å; V435-F518 WeakPolarHBondContact O-CZ 3.33Å; L490-F518 HydrophobicContact CD1-CB 4.21Å; T516-F518 PolarHBondContact O-N 3.2Å; F518-L520 PolarHBondContact O-N 3.34Å; F518-S521 VanDerWaalsContact C-OG 3.24Å; F518-S521 WeakPolarHBondContact CA-OG 3.4Å; F518-S521 VanDerWaalsContact CB-OG 3.31Å; F518-S521 WeakPolarHBondContact CB-OG 3.35Å; F518-S521 WeakPolarHBondContact O-CB 3.37Å; F518-S521 PolarHBondContact O-N 3.47Å; F518-S521 VanDerWaalsContact O-N 3.16Å; F518-S521 PolarHBondContact O-OG 3.36Å
519G50.4Low64.9Low12 Ų1251.2 Ų51.212%0.12427%0.271CS..G310 helixtrans-81.19.7172.300000116.4M426 D517M426-G519 WeakPolarHBondContact SD-CA 2.89Å; D517-G519 PolarHBondContact O-N 2.53Å
520L51.8Low63.5Low54 Ų5450 Ų5028%0.28326%0.256SS..G310 helixtrans-121.15.7165.8-59.4169.5000110.7F390 M414 R498 F518F390-L520 HydrophobicContact CD1-CD1 3.6Å; F390-L520 HydrophobicContact CD2-CD1 3.57Å; F390-L520 HydrophobicContact CE1-CD1 3.51Å; F390-L520 HydrophobicContact CE2-CD1 3.48Å; F390-L520 VanDerWaalsContact CE2-CD1 3.48Å; F390-L520 HydrophobicContact CG-CD1 3.63Å; F390-L520 HydrophobicContact CZ-CD1 3.45Å; F390-L520 VanDerWaalsContact CZ-CD1 3.45Å; M414-L520 HydrophobicContact CE-CD2 4.12Å; R498-L520 PolarHBondContact NH1-O 2.83Å; F518-L520 PolarHBondContact O-N 3.34Å
521S52.3Low62Low3 Ų345.5 Ų45.52%0.02123%0.233CC..PPolyproline II helixtrans-68.3143.9170.6-56.80000109.4I496 H497 F518I496-S521 WeakPolarHBondContact O-CA 3.22Å; I496-S521 WeakPolarHBondContact O-CB 3.27Å; I496-S521 PolarHBondContact O-OG 3.01Å; H497-S521 WeakPolarHBondContact CA-OG 3.21Å; F518-S521 VanDerWaalsContact C-OG 3.24Å; F518-S521 WeakPolarHBondContact CA-OG 3.4Å; F518-S521 VanDerWaalsContact CB-OG 3.31Å; F518-S521 WeakPolarHBondContact CB-OG 3.35Å; F518-S521 WeakPolarHBondContact O-CB 3.37Å; F518-S521 PolarHBondContact O-N 3.47Å; F518-S521 VanDerWaalsContact O-N 3.16Å; F518-S521 PolarHBondContact O-OG 3.36Å
522R53.5Low60Low97 Ų9748.6 Ų48.637%0.36625%0.251SS..EExtended strand (participates in β ladder)trans-101.7136.9173.7-69.9-167.2-164.8-144.7-4109.7I496 V524 Y529I496-R522 PolarHBondContact N-O 3.49Å; I496-R522 PolarHBondContact O-N 2.97Å; R522-V524 HydrophobicContact CB-CG2 3.91Å; R522-V524 PolarHBondContact O-N 3.31Å; R522-Y529 VanDerWaalsContact CZ-CE2 3.4Å; R522-Y529 VanDerWaalsContact NE-CZ 3.29Å; R522-Y529 VanDerWaalsContact NH1-CZ 3.32Å; R522-Y529 PolarHBondContact NH1-OH 3.36Å; R522-Y529 PolarHBondContact NH2-OH 2.97Å
523Y41.8Very low57.5Low117 Ų11752.1 Ų52.146%0.45928%0.284SS..EExtended strand (participates in β ladder)trans-68.3124.8160.4-178.1-107.8000109.1Q494 Y495 L525Q494-Y523 HydrophobicContact CB-CE2 4.15Å; Y495-Y523 HydrophobicContact CD2-CD2 4.05Å; Y495-Y523 AromaticContact CE2-CD2 3.68Å; Y495-Y523 HydrophobicContact CE2-CD2 3.68Å; Y495-Y523 HydrophobicContact CE2-CG 4.39Å; Y523-L525 HydrophobicContact CE1-CD1 4.43Å; Y523-L525 HydrophobicContact CE1-CD2 3.88Å; Y523-L525 HydrophobicContact CE1-CG 3.75Å; Y523-L525 VanDerWaalsContact OH-CD2 3.24Å; Y523-L525 WeakPolarHBondContact OH-CD2 3.37Å
524V43.2Very low55Low16 Ų1656 Ų5610%0.09732%0.323CS..  trans-137.7111.8-176.6-176.70000109Q494 I496 R522 D526 D527 E528Q494-V524 PolarHBondContact O-N 3.05Å; I496-V524 HydrophobicContact CD1-CB 3.89Å; I496-V524 HydrophobicContact CD1-CG1 4.31Å; I496-V524 HydrophobicContact CD1-CG2 3.8Å; R522-V524 HydrophobicContact CB-CG2 3.91Å; R522-V524 PolarHBondContact O-N 3.31Å; V524-D526 VanDerWaalsContact C-N 3.25Å; V524-D526 PolarHBondContact O-N 3.5Å; V524-D527 PolarHBondContact O-N 2.88Å; V524-E528 VanDerWaalsContact CG1-O 3.31Å; V524-E528 WeakPolarHBondContact CG1-O 3.44Å
525L29.2Very low53Low124 Ų12456.5 Ų56.565%0.64933%0.33SS*.THydrogen-bonded Turntrans-64.5-26.9-177.6-76.7160.2000113.9Y523Y523-L525 HydrophobicContact CE1-CD1 4.43Å; Y523-L525 HydrophobicContact CE1-CD2 3.88Å; Y523-L525 HydrophobicContact CE1-CG 3.75Å; Y523-L525 VanDerWaalsContact OH-CD2 3.24Å; Y523-L525 WeakPolarHBondContact OH-CD2 3.37Å
526D37.1Very low51.4Low114 Ų11465.3 Ų65.361%0.6137%0.368SS*.THydrogen-bonded Turntrans-11219.4-175-63.9-28.1000112.8V524 E528V524-D526 VanDerWaalsContact C-N 3.25Å; V524-D526 PolarHBondContact O-N 3.5Å; D526-E528 PolarHBondContact O-N 2.92Å
527D42Very low50.6Low44 Ų4467.2 Ų67.224%0.23538%0.375CS..SBendtrans49.216.2179.8-164.731.1000116V524 S553 S554V524-D527 PolarHBondContact O-N 2.88Å; D527-S553 WeakPolarHBondContact O-CA 3.44Å; D527-S553 WeakPolarHBondContact O-CB 3.49Å; D527-S554 VanDerWaalsContact CG-OG 3.31Å; D527-S554 WeakPolarHBondContact OD1-CB 3.37Å; D527-S554 PolarHBondContact OD1-N 3.31Å; D527-S554 PolarHBondContact OD1-OG 3.01Å; D527-S554 WeakPolarHBondContact OD2-CB 3.45Å; D527-S554 PolarHBondContact OD2-OG 3.14Å
528E47.3Very low51.2Low131 Ų13166.1 Ų66.161%0.61237%0.371SS*.  trans-133.2126.8176.9-75-159.415700111.5V524 D526 F552V524-E528 VanDerWaalsContact CG1-O 3.31Å; V524-E528 WeakPolarHBondContact CG1-O 3.44Å; D526-E528 PolarHBondContact O-N 2.92Å; E528-F552 CarbonylContact C-O 3.57Å; E528-F552 WeakPolarHBondContact CA-O 3.29Å
529Y55.5Low52.7Low32 Ų3266.9 Ų66.913%0.12538%0.376CS..EExtended strand (participates in β ladder)trans-131.3121.4177.9174.4-105.5000111.4R522 S531 F552R522-Y529 VanDerWaalsContact CZ-CE2 3.4Å; R522-Y529 VanDerWaalsContact NE-CZ 3.29Å; R522-Y529 VanDerWaalsContact NH1-CZ 3.32Å; R522-Y529 PolarHBondContact NH1-OH 3.36Å; R522-Y529 PolarHBondContact NH2-OH 2.97Å; Y529-S531 WeakPolarHBondContact OH-CA 3.32Å; Y529-F552 HydrophobicContact CD1-CB 4.29Å; Y529-F552 HydrophobicContact CD1-CD2 4.01Å; Y529-F552 HydrophobicContact CD1-CG 4.46Å; Y529-F552 HydrophobicContact CE1-CD2 4.42Å; Y529-F552 PolarHBondContact N-O 3.17Å; Y529-F552 PolarHBondContact O-N 3.43Å
530T56.6Low54.9Low54 Ų5467.9 Ų67.933%0.33138%0.376SS..EExtended strand (participates in β ladder)trans-99.9118.3172.3-410000110.1K18 C550K18-T530 PolarHBondContact NZ-OG1 3.07Å; T530-C550 WeakPolarHBondContact CA-O 3.26Å
531S52.1Low57.1Low13 Ų1366.4 Ų66.49%0.09137%0.366CS..PPolyproline II helixtrans-76.9153.5177.2-156.60000112.8Y529 S535 C550Y529-S531 WeakPolarHBondContact OH-CA 3.32Å; S531-S535 WeakPolarHBondContact CB-OG 3.42Å; S531-S535 WeakPolarHBondContact OG-CB 3.47Å; S531-S535 PolarHBondContact OG-OG 2.75Å; S531-C550 PolarHBondContact N-O 2.9Å
532S45Very low59.1Low87 Ų8766.6 Ų66.661%0.60837%0.368SS*.PPolyproline II helixtrans-67.6140.4173.649.60000111G534 S535S532-G534 PolarHBondContact O-N 3.27Å; S532-S535 PolarHBondContact O-N 2.99Å; S532-S535 PolarHBondContact O-OG 2.72Å
533A38.4Very low61.1Low106 Ų10662.1 Ų62.188%0.87635%0.351SS*.THydrogen-bonded Turntrans-52.4128.2178.400000111.5
534G44.5Very low63.6Low80 Ų8057.2 Ų57.283%0.82533%0.333SS*.THydrogen-bonded Turntrans102.41.6179.900000116.1S532S532-G534 PolarHBondContact O-N 3.27Å
535S53Low66Low36 Ų3657.8 Ų57.825%0.25234%0.335SS..  trans-70.9134.6171.555.10000111.5S531 S532 F537S531-S535 WeakPolarHBondContact CB-OG 3.42Å; S531-S535 WeakPolarHBondContact OG-CB 3.47Å; S531-S535 PolarHBondContact OG-OG 2.75Å; S532-S535 PolarHBondContact O-N 2.99Å; S532-S535 PolarHBondContact O-OG 2.72Å; S535-F537 VanDerWaalsContact O-CD1 3.28Å; S535-F537 WeakPolarHBondContact O-CD1 3.49Å
536K62Low69Low184 Ų18451.9 Ų51.980%0.830%0.304SS*.  trans-76.8128.9175.5-65.2-176.8179.9-179.30109.3
537F72.7Confident71.5Confident56 Ų5647.3 Ų47.325%0.24628%0.28CS..  trans-138.1159.2178.357.2-100.2000111.1S535 V539 V546 L547 F552S535-F537 VanDerWaalsContact O-CD1 3.28Å; S535-F537 WeakPolarHBondContact O-CD1 3.49Å; F537-V539 HydrophobicContact CD2-CG2 4.39Å; F537-V539 HydrophobicContact CE2-CG2 4.07Å; F537-V539 PolarHBondContact O-N 2.76Å; F537-V546 HydrophobicContact CD2-CG1 4.15Å; F537-V546 HydrophobicContact CE2-CG1 4.42Å; F537-V546 HydrophobicContact CG-CG1 4.43Å; F537-L547 HydrophobicContact CE2-CD2 3.77Å; F537-F552 HydrophobicContact CB-CZ 4.04Å; F537-F552 HydrophobicContact CG-CZ 4.46Å
538P87.5Confident73.6Confident23 Ų2349.3 Ų49.315%0.14929%0.29CS..  trans-77.886.5-173.635-41.4000112.1D499 R503 R540 W541 S542D499-P538 WeakPolarHBondContact OD1-CB 2.86Å; D499-P538 VanDerWaalsContact OD1-CG 3.23Å; D499-P538 WeakPolarHBondContact OD1-CG 3.43Å; R503-P538 VanDerWaalsContact NH2-CB 3.32Å; P538-R540 VanDerWaalsContact C-N 3.26Å; P538-R540 PolarHBondContact O-N 3.32Å; P538-W541 HydrophobicContact CB-CB 4.4Å; P538-W541 HydrophobicContact CB-CE3 3.95Å; P538-W541 HydrophobicContact CG-CB 4.42Å; P538-W541 PolarHBondContact O-N 3.3Å; P538-S542 PolarHBondContact O-N 3.18Å; P538-S542 PolarHBondContact O-OG 2.88Å
539V92.1Very high75.4Confident21 Ų2150 Ų5013%0.12729%0.288CS..G310 helixtrans-46-43.9-174.5176.30000113.8F537 W541 S542 L547 N581 I584 V585F537-V539 HydrophobicContact CD2-CG2 4.39Å; F537-V539 HydrophobicContact CE2-CG2 4.07Å; F537-V539 PolarHBondContact O-N 2.76Å; V539-W541 VanDerWaalsContact C-N 3.26Å; V539-W541 PolarHBondContact O-N 2.96Å; V539-S542 PolarHBondContact O-N 2.89Å; V539-L547 HydrophobicContact CB-CD2 4.46Å; V539-L547 HydrophobicContact CG1-CD2 4Å; V539-N581 HydrophobicContact CB-CB 4.31Å; V539-N581 HydrophobicContact CG1-CB 4.01Å; V539-N581 HydrophobicContact CG2-CB 4.23Å; V539-I584 HydrophobicContact CG1-CB 4.29Å; V539-I584 HydrophobicContact CG1-CG2 4.03Å; V539-V585 HydrophobicContact CG1-CG2 4.14Å
540R95.9Very high76.7Confident34 Ų3449.5 Ų49.513%0.12829%0.289CS..G310 helixtrans-71.5-17.4-175.4-52.4179.5169-80.1-7114.5P538 P575 Y576 L579 I584P538-R540 VanDerWaalsContact C-N 3.26Å; P538-R540 PolarHBondContact O-N 3.32Å; R540-P575 HydrophobicContact CB-CB 4.34Å; R540-P575 WeakPolarHBondContact CD-O 3.2Å; R540-P575 PolarHBondContact NH1-O 3.07Å; R540-Y576 PolarHBondContact NH1-O 3.41Å; R540-L579 PolarHBondContact NH1-O 3.37Å; R540-L579 PolarHBondContact NH2-O 3.42Å; R540-I584 HydrophobicContact CG-CD1 3.83Å
541W96.9Very high78Confident23 Ų2351.3 Ų51.39%0.08729%0.292CS..G310 helixtrans-106.9-1.6178.6-68.1-100.7000112.3A501 P538 V539 W559 A560 V563 E567 L574 P575A501-W541 HydrophobicContact CB-CD2 4.21Å; A501-W541 HydrophobicContact CB-CG 4.2Å; A501-W541 HydrophobicContact CB-CZ2 4.39Å; P538-W541 HydrophobicContact CB-CB 4.4Å; P538-W541 HydrophobicContact CB-CE3 3.95Å; P538-W541 HydrophobicContact CG-CB 4.42Å; P538-W541 PolarHBondContact O-N 3.3Å; V539-W541 VanDerWaalsContact C-N 3.26Å; V539-W541 PolarHBondContact O-N 2.96Å; W541-W559 VanDerWaalsContact O-CD1 3.28Å; W541-A560 HydrophobicContact CB-CB 4.41Å; W541-V563 VanDerWaalsContact CD1-CG1 3.43Å; W541-V563 HydrophobicContact CG-CB 4.46Å; W541-V563 HydrophobicContact CG-CG1 4Å; W541-E567 WeakPolarHBondContact CZ2-OE1 2.88Å; W541-E567 PolarHBondContact NE1-OE2 3.46Å; W541-L574 HydrophobicContact CH2-CD1 4.18Å; W541-P575 HydrophobicContact CZ2-CG 3.97Å
542S95.1Very high79.6Confident7 Ų751 Ų515%0.04929%0.29CS..  trans-93.7137.4-172.3-64.30000111.6P538 V539P538-S542 PolarHBondContact O-N 3.18Å; P538-S542 PolarHBondContact O-OG 2.88Å; V539-S542 PolarHBondContact O-N 2.89Å
543P96.3Very high81.8Confident2 Ų247.5 Ų47.51%0.01327%0.265CS..  trans-75.6164.7173.934-40.2000112.5E545 V546 L547 W559P543-E545 VanDerWaalsContact C-N 3.29Å; P543-E545 WeakPolarHBondContact CB-OE1 3.5Å; P543-E545 WeakPolarHBondContact CB-OE2 3.33Å; P543-E545 HydrophobicContact CG-CG 4.43Å; P543-E545 WeakPolarHBondContact CG-OE1 3.43Å; P543-E545 PolarHBondContact O-N 3.17Å; P543-E545 VanDerWaalsContact O-N 3.17Å; P543-V546 HydrophobicContact CG-CB 4Å; P543-V546 HydrophobicContact CG-CG2 3.61Å; P543-V546 PolarHBondContact O-N 3.25Å; P543-L547 WeakPolarHBondContact O-CG 3.42Å; P543-L547 PolarHBondContact O-N 2.78Å; P543-W559 HydrophobicContact CB-CB 3.85Å; P543-W559 HydrophobicContact CB-CD2 3.51Å; P543-W559 HydrophobicContact CB-CE3 3.7Å; P543-W559 HydrophobicContact CB-CG 3.58Å; P543-W559 HydrophobicContact CB-CZ3 4.39Å; P543-W559 HydrophobicContact CG-CB 4.24Å; P543-W559 HydrophobicContact CG-CG 4.3Å
544P94.3Very high84.4Confident14 Ų1442.7 Ų42.79%0.09122%0.224CC..Hα-helixtrans-49.9-41.9-179.4-27.733.4000114.7V546 L547 L548 W559 V588P544-V546 VanDerWaalsContact C-N 3.33Å; P544-V546 PolarHBondContact O-N 2.98Å; P544-L547 PolarHBondContact O-N 3.43Å; P544-L548 WeakPolarHBondContact O-CB 3.38Å; P544-L548 VanDerWaalsContact O-CG 3.28Å; P544-L548 WeakPolarHBondContact O-CG 3.48Å; P544-L548 PolarHBondContact O-N 2.77Å; P544-W559 HydrophobicContact CG-CH2 4.17Å; P544-W559 HydrophobicContact CG-CZ3 4.39Å; P544-V588 HydrophobicContact CG-CG1 4.15Å
545E93.6Very high86.9Confident28 Ų2840.3 Ų40.313%0.13119%0.191CC..Hα-helixtrans-69.7-27.5-179.169.8-78.1-179.300113.8P543 Y549 C550 K551 R619P543-E545 VanDerWaalsContact C-N 3.29Å; P543-E545 WeakPolarHBondContact CB-OE1 3.5Å; P543-E545 WeakPolarHBondContact CB-OE2 3.33Å; P543-E545 HydrophobicContact CG-CG 4.43Å; P543-E545 WeakPolarHBondContact CG-OE1 3.43Å; P543-E545 PolarHBondContact O-N 3.17Å; P543-E545 VanDerWaalsContact O-N 3.17Å; E545-Y549 HydrophobicContact CB-CD2 4.44Å; E545-Y549 CarbonylContact O-C 3.53Å; E545-Y549 WeakPolarHBondContact O-CA 3.47Å; E545-Y549 WeakPolarHBondContact O-CB 3.18Å; E545-Y549 PolarHBondContact O-N 3.31Å; E545-Y549 VanDerWaalsContact O-N 3.07Å; E545-C550 PolarHBondContact O-N 3.47Å; E545-K551 HydrophobicContact CB-CB 4.47Å; E545-K551 HydrophobicContact CG-CB 4.41Å; E545-K551 PolarHBondContact O-N 3.21Å; E545-R619 IonicContact OE1-CZ 2.99Å; E545-R619 IonicContact OE1-NH1 2.65Å; E545-R619 PolarHBondContact OE1-NH1 2.93Å; E545-R619 IonicContact OE1-NH2 3.23Å; E545-R619 PolarHBondContact OE1-NH2 3.43Å; E545-R619 VanDerWaalsContact OE1-NH2 3.13Å; E545-R619 IonicContact OE2-CZ 3.03Å; E545-R619 IonicContact OE2-NH1 2.75Å; E545-R619 IonicContact OE2-NH2 2.86Å; E545-R619 PolarHBondContact OE2-NH2 3.46Å
546V91.2Very high88.9Confident1 Ų138.8 Ų38.81%0.00618%0.181CC..Hα-helixtrans-74.1-46.2169.6172.70000109.6F537 P543 P544 L548 C550 K551 F552F537-V546 HydrophobicContact CD2-CG1 4.15Å; F537-V546 HydrophobicContact CE2-CG1 4.42Å; F537-V546 HydrophobicContact CG-CG1 4.43Å; P543-V546 HydrophobicContact CG-CB 4Å; P543-V546 HydrophobicContact CG-CG2 3.61Å; P543-V546 PolarHBondContact O-N 3.25Å; P544-V546 VanDerWaalsContact C-N 3.33Å; P544-V546 PolarHBondContact O-N 2.98Å; V546-L548 VanDerWaalsContact C-N 3.35Å; V546-L548 PolarHBondContact O-N 2.79Å; V546-C550 WeakPolarHBondContact O-CA 3.45Å; V546-C550 PolarHBondContact O-N 2.65Å; V546-K551 WeakPolarHBondContact CG2-O 3.5Å; V546-F552 HydrophobicContact CG1-CD1 4.29Å; V546-F552 HydrophobicContact CG1-CE1 3.63Å; V546-F552 HydrophobicContact CG1-CE2 4.18Å; V546-F552 HydrophobicContact CG1-CZ 3.56Å; V546-F552 HydrophobicContact CG2-CD1 3.97Å; V546-F552 HydrophobicContact CG2-CE1 4.14Å; V546-F552 HydrophobicContact CG2-CG 4.29Å
547L89.9Confident90.6Very high18 Ų1830.2 Ų30.29%0.09414%0.144CC..Hα-helixtrans-61-41.7-178.1-64.4178.2000112.5F537 V539 P543 P544 V585 V588F537-L547 HydrophobicContact CE2-CD2 3.77Å; V539-L547 HydrophobicContact CB-CD2 4.46Å; V539-L547 HydrophobicContact CG1-CD2 4Å; P543-L547 WeakPolarHBondContact O-CG 3.42Å; P543-L547 PolarHBondContact O-N 2.78Å; P544-L547 PolarHBondContact O-N 3.43Å; L547-V585 HydrophobicContact CB-CG1 4.46Å; L547-V585 HydrophobicContact CB-CG2 4.43Å; L547-V585 HydrophobicContact CD1-CG2 4.41Å; L547-V585 HydrophobicContact CD2-CG2 4.14Å; L547-V588 HydrophobicContact CD1-CB 4.38Å; L547-V588 HydrophobicContact CD1-CG1 4.28Å
548L86.2Confident91.8Very high85 Ų8527.5 Ų27.545%0.44513%0.132SC..Hα-helixtrans-91.6-35.3-174.1-62.7174.1000113P544 V546 V585P544-L548 WeakPolarHBondContact O-CB 3.38Å; P544-L548 VanDerWaalsContact O-CG 3.28Å; P544-L548 WeakPolarHBondContact O-CG 3.48Å; P544-L548 PolarHBondContact O-N 2.77Å; V546-L548 VanDerWaalsContact C-N 3.35Å; V546-L548 PolarHBondContact O-N 2.79Å; L548-V585 HydrophobicContact CD2-CG1 4.44Å
549Y84Confident92.3Very high145 Ų14526.5 Ų26.557%0.56913%0.125SC*.Hα-helixtrans-128.92.8-168-47-62.3000114E545 K551E545-Y549 HydrophobicContact CB-CD2 4.44Å; E545-Y549 CarbonylContact O-C 3.53Å; E545-Y549 WeakPolarHBondContact O-CA 3.47Å; E545-Y549 WeakPolarHBondContact O-CB 3.18Å; E545-Y549 PolarHBondContact O-N 3.31Å; E545-Y549 VanDerWaalsContact O-N 3.07Å; Y549-K551 PolarHBondContact O-N 3.13Å; Y549-K551 VanDerWaalsContact O-N 3.17Å
550C82.8Confident92.6Very high22 Ų2225.8 Ų25.815%0.14912%0.122CC..  trans52.233.7-176.3-640000113.1T530 S531 E545 V546 F552T530-C550 WeakPolarHBondContact CA-O 3.26Å; S531-C550 PolarHBondContact N-O 2.9Å; E545-C550 PolarHBondContact O-N 3.47Å; V546-C550 WeakPolarHBondContact O-CA 3.45Å; V546-C550 PolarHBondContact O-N 2.65Å; C550-F552 WeakPolarHBondContact O-CD2 3.35Å
551K84.6Confident92.7Very high93 Ų9324.2 Ų24.240%0.40412%0.116SC..EExtended strand (participates in β ladder)trans-92.4107178.9-72.2-175.4175.5-167.20110.8E545 V546 Y549E545-K551 HydrophobicContact CB-CB 4.47Å; E545-K551 HydrophobicContact CG-CB 4.41Å; E545-K551 PolarHBondContact O-N 3.21Å; V546-K551 WeakPolarHBondContact CG2-O 3.5Å; Y549-K551 PolarHBondContact O-N 3.13Å; Y549-K551 VanDerWaalsContact O-N 3.17Å
552F86.1Confident92.8Very high7 Ų723.1 Ų23.13%0.03111%0.111CC..EExtended strand (participates in β ladder)trans-97.8145.2174.9-61.5-93.9000110.5I496 R498 E528 Y529 F537 V546 C550 S556I496-F552 HydrophobicContact CG2-CB 4.41Å; R498-F552 HydrophobicContact CB-CD1 3.82Å; R498-F552 HydrophobicContact CB-CE1 4.08Å; R498-F552 HydrophobicContact CG-CB 4.21Å; R498-F552 HydrophobicContact CG-CD1 3.84Å; R498-F552 HydrophobicContact CG-CG 4.15Å; E528-F552 CarbonylContact C-O 3.57Å; E528-F552 WeakPolarHBondContact CA-O 3.29Å; Y529-F552 HydrophobicContact CD1-CB 4.29Å; Y529-F552 HydrophobicContact CD1-CD2 4.01Å; Y529-F552 HydrophobicContact CD1-CG 4.46Å; Y529-F552 HydrophobicContact CE1-CD2 4.42Å; Y529-F552 PolarHBondContact N-O 3.17Å; Y529-F552 PolarHBondContact O-N 3.43Å; F537-F552 HydrophobicContact CB-CZ 4.04Å; F537-F552 HydrophobicContact CG-CZ 4.46Å; V546-F552 HydrophobicContact CG1-CD1 4.29Å; V546-F552 HydrophobicContact CG1-CE1 3.63Å; V546-F552 HydrophobicContact CG1-CE2 4.18Å; V546-F552 HydrophobicContact CG1-CZ 3.56Å; V546-F552 HydrophobicContact CG2-CD1 3.97Å; V546-F552 HydrophobicContact CG2-CE1 4.14Å; V546-F552 HydrophobicContact CG2-CG 4.29Å; C550-F552 WeakPolarHBondContact O-CD2 3.35Å; F552-S556 WeakPolarHBondContact CA-OG 3.49Å
553S89.9Confident93Very high13 Ų1322.8 Ų22.89%0.09111%0.109CC..  trans-158.6172.1176.956.70000109.9D527 K555 S556 D557D527-S553 WeakPolarHBondContact O-CA 3.44Å; D527-S553 WeakPolarHBondContact O-CB 3.49Å; S553-K555 PolarHBondContact O-N 3.3Å; S553-K555 WeakPolarHBondContact OG-CB 3.47Å; S553-K555 PolarHBondContact OG-N 2.83Å; S553-S556 PolarHBondContact N-OG 3.28Å; S553-S556 WeakPolarHBondContact O-CA 3.47Å; S553-S556 WeakPolarHBondContact O-CB 3.45Å; S553-S556 PolarHBondContact O-N 3.45Å; S553-S556 PolarHBondContact O-OG 3.44Å; S553-S556 PolarHBondContact OG-N 2.87Å; S553-D557 PolarHBondContact O-N 2.86Å
554S93.1Very high93.1Very high4 Ų422.7 Ų22.73%0.02811%0.108CC..Hα-helixtrans-47.5-42164.9650000111.3D527 S556 D557 I558D527-S554 VanDerWaalsContact CG-OG 3.31Å; D527-S554 WeakPolarHBondContact OD1-CB 3.37Å; D527-S554 PolarHBondContact OD1-N 3.31Å; D527-S554 PolarHBondContact OD1-OG 3.01Å; D527-S554 WeakPolarHBondContact OD2-CB 3.45Å; D527-S554 PolarHBondContact OD2-OG 3.14Å; S554-S556 PolarHBondContact O-N 3.16Å; S554-D557 WeakPolarHBondContact O-CA 3.33Å; S554-D557 WeakPolarHBondContact O-CB 3.49Å; S554-D557 PolarHBondContact O-N 2.96Å; S554-I558 WeakPolarHBondContact O-CD1 3.39Å; S554-I558 PolarHBondContact O-N 2.81Å
555K97.2Very high93.3Very high30 Ų3022 Ų2213%0.1310%0.104CC..Hα-helixtrans-63.3-28178.4-55.2-53.1-172.4174.70113.5S553 I558 W559 A616 R619 P620S553-K555 PolarHBondContact O-N 3.3Å; S553-K555 WeakPolarHBondContact OG-CB 3.47Å; S553-K555 PolarHBondContact OG-N 2.83Å; K555-I558 HydrophobicContact CD-CD1 3.57Å; K555-W559 PolarHBondContact O-N 3.24Å; K555-A616 HydrophobicContact CB-CB 3.88Å; K555-A616 HydrophobicContact CG-CB 4.37Å; K555-A616 WeakPolarHBondContact CG-O 3.28Å; K555-R619 HydrophobicContact CD-CB 4.44Å; K555-R619 PolarHBondContact NZ-O 2.98Å; K555-R619 WeakPolarHBondContact O-CD 3.5Å; K555-R619 PolarHBondContact O-NH1 3.48Å; K555-P620 PolarHBondContact NZ-O 2.8Å
556S95.7Very high93.6Very high5 Ų520.9 Ų20.94%0.03510%0.099CC..Hα-helixtrans-74.4-33.617273.40000112.8F552 S553 S554 I558 W559 A560F552-S556 WeakPolarHBondContact CA-OG 3.49Å; S553-S556 PolarHBondContact N-OG 3.28Å; S553-S556 WeakPolarHBondContact O-CA 3.47Å; S553-S556 WeakPolarHBondContact O-CB 3.45Å; S553-S556 PolarHBondContact O-N 3.45Å; S553-S556 PolarHBondContact O-OG 3.44Å; S553-S556 PolarHBondContact OG-N 2.87Å; S554-S556 PolarHBondContact O-N 3.16Å; S556-I558 VanDerWaalsContact C-N 3.35Å; S556-W559 WeakPolarHBondContact O-CB 3.41Å; S556-W559 PolarHBondContact O-N 3.11Å; S556-A560 PolarHBondContact O-N 2.86Å
557D96.7Very high93.9Very high3 Ų321 Ų212%0.01610%0.099CC..Hα-helixtrans-70.7-32.9173-71.6-28.3000111.7M487 I496 H497 R498 S553 S554 W559 A560 Y561 F622M487-D557 HydrophobicContact CE-CB 3.81Å; I496-D557 WeakPolarHBondContact CA-OD2 3.32Å; I496-D557 VanDerWaalsContact CG2-OD2 3.29Å; I496-D557 WeakPolarHBondContact CG2-OD2 3.41Å; H497-D557 PolarHBondContact N-OD2 3.46Å; R498-D557 WeakPolarHBondContact CA-OD1 2.99Å; R498-D557 PolarHBondContact N-OD1 2.63Å; S553-D557 PolarHBondContact O-N 2.86Å; S554-D557 WeakPolarHBondContact O-CA 3.33Å; S554-D557 WeakPolarHBondContact O-CB 3.49Å; S554-D557 PolarHBondContact O-N 2.96Å; D557-W559 VanDerWaalsContact C-N 3.33Å; D557-W559 PolarHBondContact O-N 3.17Å; D557-A560 CarbonylContact O-C 3.51Å; D557-A560 WeakPolarHBondContact O-CB 3.26Å; D557-A560 PolarHBondContact O-N 3.26Å; D557-Y561 WeakPolarHBondContact O-CB 3.47Å; D557-Y561 PolarHBondContact O-N 3.03Å; D557-F622 HydrophobicContact CB-CE2 3.78Å; D557-F622 HydrophobicContact CB-CZ 4.02Å
558I98.5Very high94.3Very high0 Ų020.1 Ų20.10%09%0.094CC..Hα-helixtrans-60.6-42.9172.6-73.3146.2000111.2S554 K555 S556 A560 Y561 G562 C611 R619 P620 F622 L625S554-I558 WeakPolarHBondContact O-CD1 3.39Å; S554-I558 PolarHBondContact O-N 2.81Å; K555-I558 HydrophobicContact CD-CD1 3.57Å; S556-I558 VanDerWaalsContact C-N 3.35Å; I558-A560 VanDerWaalsContact C-N 3.33Å; I558-A560 PolarHBondContact O-N 2.88Å; I558-Y561 WeakPolarHBondContact O-CB 3.42Å; I558-Y561 PolarHBondContact O-N 3.47Å; I558-G562 PolarHBondContact O-N 2.79Å; I558-C611 HydrophobicContact CG2-CB 4.06Å; I558-C611 WeakPolarHBondContact O-CB 3.5Å; I558-R619 HydrophobicContact CG2-CB 3.87Å; I558-P620 WeakPolarHBondContact CD1-O 2.85Å; I558-P620 HydrophobicContact CG2-CG 4.35Å; I558-F622 HydrophobicContact CD1-CD2 4.38Å; I558-F622 HydrophobicContact CD1-CE2 4.49Å; I558-F622 HydrophobicContact CG1-CD2 3.86Å; I558-F622 HydrophobicContact CG1-CE1 4.44Å; I558-F622 HydrophobicContact CG1-CE2 3.69Å; I558-F622 HydrophobicContact CG1-CG 4.32Å; I558-F622 HydrophobicContact CG1-CZ 3.99Å; I558-L625 HydrophobicContact CG1-CD1 4.26Å; I558-L625 HydrophobicContact CG2-CD1 4.06Å
559W98.6Very high94.9Very high2 Ų216.2 Ų16.21%0.0087%0.074CC..Hα-helixtrans-58.8-47.2172.7178.7-73.3000111.5W541 P543 P544 K555 S556 D557 Y561 G562 V563 V588 C611 W612W541-W559 VanDerWaalsContact O-CD1 3.28Å; P543-W559 HydrophobicContact CB-CB 3.85Å; P543-W559 HydrophobicContact CB-CD2 3.51Å; P543-W559 HydrophobicContact CB-CE3 3.7Å; P543-W559 HydrophobicContact CB-CG 3.58Å; P543-W559 HydrophobicContact CB-CZ3 4.39Å; P543-W559 HydrophobicContact CG-CB 4.24Å; P543-W559 HydrophobicContact CG-CG 4.3Å; P544-W559 HydrophobicContact CG-CH2 4.17Å; P544-W559 HydrophobicContact CG-CZ3 4.39Å; K555-W559 PolarHBondContact O-N 3.24Å; S556-W559 WeakPolarHBondContact O-CB 3.41Å; S556-W559 PolarHBondContact O-N 3.11Å; D557-W559 VanDerWaalsContact C-N 3.33Å; D557-W559 PolarHBondContact O-N 3.17Å; W559-Y561 VanDerWaalsContact C-N 3.28Å; W559-Y561 PolarHBondContact O-N 2.73Å; W559-G562 PolarHBondContact O-N 2.85Å; W559-G562 VanDerWaalsContact O-N 3.15Å; W559-V563 PolarHBondContact O-N 3.08Å; W559-V563 VanDerWaalsContact O-N 3.13Å; W559-V588 HydrophobicContact CH2-CG1 3.9Å; W559-V588 HydrophobicContact CZ2-CG1 3.64Å; W559-C611 WeakPolarHBondContact CA-O 3.37Å; W559-W612 HydrophobicContact CD2-CB 4.46Å; W559-W612 AromaticContact CD2-CD1 3.63Å; W559-W612 HydrophobicContact CD2-CG 4.39Å; W559-W612 AromaticContact CE2-CD1 3.79Å; W559-W612 HydrophobicContact CE3-CB 4.03Å; W559-W612 HydrophobicContact CE3-CG 4.43Å; W559-W612 AromaticContact CG-CD1 3.9Å; W559-W612 HydrophobicContact CH2-CB 4.16Å; W559-W612 HydrophobicContact CZ3-CB 3.88Å; W559-W612 WeakPolarHBondContact CZ3-O 3.39Å; W559-W612 PolarHBondContact O-NE1 3.37Å
560A98.3Very high95.6Very high6 Ų610.1 Ų10.15%0.055%0.052CC..Hα-helixtrans-61.9-36.5178.800000111.9L500 W541 S556 D557 I558 V563 L564L500-A560 HydrophobicContact CB-CB 4.05Å; W541-A560 HydrophobicContact CB-CB 4.41Å; S556-A560 PolarHBondContact O-N 2.86Å; D557-A560 CarbonylContact O-C 3.51Å; D557-A560 WeakPolarHBondContact O-CB 3.26Å; D557-A560 PolarHBondContact O-N 3.26Å; I558-A560 VanDerWaalsContact C-N 3.33Å; I558-A560 PolarHBondContact O-N 2.88Å; A560-V563 PolarHBondContact O-N 2.97Å; A560-L564 PolarHBondContact O-N 3.42Å
561Y98.7Very high96.3Very high0 Ų011.4 Ų11.40%06%0.057CC..Hα-helixtrans-62.1-43.1172.4174.9-102000112.1C480 V483 L500 D557 I558 W559 V563 L564 M565 F622 L625C480-Y561 PolarHBondContact O-OH 3.28Å; V483-Y561 HydrophobicContact CB-CE2 4.23Å; V483-Y561 HydrophobicContact CG1-CD2 3.88Å; V483-Y561 HydrophobicContact CG1-CE2 3.99Å; L500-Y561 HydrophobicContact CD2-CD2 4.4Å; D557-Y561 WeakPolarHBondContact O-CB 3.47Å; D557-Y561 PolarHBondContact O-N 3.03Å; I558-Y561 WeakPolarHBondContact O-CB 3.42Å; I558-Y561 PolarHBondContact O-N 3.47Å; W559-Y561 VanDerWaalsContact C-N 3.28Å; W559-Y561 PolarHBondContact O-N 2.73Å; Y561-V563 VanDerWaalsContact C-N 3.28Å; Y561-V563 PolarHBondContact O-N 3.22Å; Y561-L564 CarbonylContact O-C 3.58Å; Y561-L564 WeakPolarHBondContact O-CB 3.48Å; Y561-L564 PolarHBondContact O-N 3.11Å; Y561-L564 VanDerWaalsContact O-N 3.1Å; Y561-M565 HydrophobicContact CD1-CG 4.26Å; Y561-M565 HydrophobicContact CD1-SD 4.13Å; Y561-M565 HydrophobicContact CE1-CG 3.77Å; Y561-M565 HydrophobicContact CE1-SD 3.35Å; Y561-M565 WeakPolarHBondContact CE1-SD 3.49Å; Y561-M565 HydrophobicContact CE2-CG 4.17Å; Y561-M565 WeakPolarHBondContact O-CG 3.37Å; Y561-M565 PolarHBondContact O-N 3.21Å; Y561-F622 HydrophobicContact CD1-CE1 4.34Å; Y561-F622 HydrophobicContact CD2-CE1 4.09Å; Y561-F622 AromaticContact CG-CE1 3.77Å; Y561-F622 HydrophobicContact CG-CE1 3.77Å; Y561-L625 HydrophobicContact CD1-CD1 3.72Å; Y561-L625 HydrophobicContact CE1-CB 4.42Å; Y561-L625 HydrophobicContact CE1-CD1 3.99Å; Y561-L625 HydrophobicContact CE1-CD2 4.37Å
562G98.8Very high96.8Very high0 Ų07 Ų70%04%0.038CC..Hα-helixtrans-57.7-41.8172.900000112.3I558 W559 M565 W566 W612I558-G562 PolarHBondContact O-N 2.79Å; W559-G562 PolarHBondContact O-N 2.85Å; W559-G562 VanDerWaalsContact O-N 3.15Å; G562-M565 PolarHBondContact O-N 2.85Å; G562-W566 PolarHBondContact O-N 2.79Å; G562-W566 VanDerWaalsContact O-N 3.12Å; G562-W612 VanDerWaalsContact O-CZ2 3.23Å; G562-W612 WeakPolarHBondContact O-CZ2 3.29Å
563V98.8Very high97.3Very high0 Ų011.8 Ų11.80%06%0.059CC..Hα-helixtrans-65.9-39.6174.4-178.50000111.5W541 W559 A560 Y561 W566 E567 P575 L594 W612W541-V563 VanDerWaalsContact CD1-CG1 3.43Å; W541-V563 HydrophobicContact CG-CB 4.46Å; W541-V563 HydrophobicContact CG-CG1 4Å; W559-V563 PolarHBondContact O-N 3.08Å; W559-V563 VanDerWaalsContact O-N 3.13Å; A560-V563 PolarHBondContact O-N 2.97Å; Y561-V563 VanDerWaalsContact C-N 3.28Å; Y561-V563 PolarHBondContact O-N 3.22Å; V563-W566 CarbonylContact O-C 3.59Å; V563-W566 WeakPolarHBondContact O-CA 3.39Å; V563-W566 WeakPolarHBondContact O-CB 3.45Å; V563-W566 PolarHBondContact O-N 3.34Å; V563-W566 VanDerWaalsContact O-N 3.15Å; V563-E567 PolarHBondContact O-N 2.84Å; V563-P575 HydrophobicContact CG1-CB 3.87Å; V563-P575 HydrophobicContact CG1-CG 3.51Å; V563-L594 HydrophobicContact CB-CD1 4.49Å; V563-L594 HydrophobicContact CG1-CD1 4.09Å; V563-L594 HydrophobicContact CG2-CD1 4.23Å; V563-W612 HydrophobicContact CG2-CZ2 4.33Å
564L98.7Very high97.6Very high0 Ų015 Ų150%07%0.074CC..Hα-helixtrans-62.2-44.4175179.2157.5000111.7V483 L500 A560 Y561 W566 E567 V568V483-L564 HydrophobicContact CB-CD2 4.5Å; V483-L564 HydrophobicContact CG1-CD1 3.95Å; V483-L564 HydrophobicContact CG1-CD2 4.25Å; V483-L564 HydrophobicContact CG2-CD2 4.32Å; L500-L564 HydrophobicContact CD1-CD1 3.9Å; L500-L564 HydrophobicContact CG-CD1 3.99Å; A560-L564 PolarHBondContact O-N 3.42Å; Y561-L564 CarbonylContact O-C 3.58Å; Y561-L564 WeakPolarHBondContact O-CB 3.48Å; Y561-L564 PolarHBondContact O-N 3.11Å; Y561-L564 VanDerWaalsContact O-N 3.1Å; L564-W566 PolarHBondContact O-N 2.97Å; L564-E567 WeakPolarHBondContact O-CA 3.37Å; L564-E567 WeakPolarHBondContact O-CB 3.36Å; L564-E567 PolarHBondContact O-N 3.44Å; L564-V568 HydrophobicContact CD2-CG2 4Å; L564-V568 WeakPolarHBondContact O-CG2 3.45Å; L564-V568 PolarHBondContact O-N 2.82Å
565M98.8Very high97.9Very high0 Ų014.8 Ų14.80%07%0.073CC..Hα-helixtrans-57.2-41.4173.6-69.4-171.574.200110.4L477 C480 Y561 G562 V568 Y569 V604 I607 M608L477-M565 HydrophobicContact CD1-CE 4.42Å; C480-M565 HydrophobicContact CB-CE 4.27Å; C480-M565 HydrophobicContact CB-CG 4.27Å; Y561-M565 HydrophobicContact CD1-CG 4.26Å; Y561-M565 HydrophobicContact CD1-SD 4.13Å; Y561-M565 HydrophobicContact CE1-CG 3.77Å; Y561-M565 HydrophobicContact CE1-SD 3.35Å; Y561-M565 WeakPolarHBondContact CE1-SD 3.49Å; Y561-M565 HydrophobicContact CE2-CG 4.17Å; Y561-M565 WeakPolarHBondContact O-CG 3.37Å; Y561-M565 PolarHBondContact O-N 3.21Å; G562-M565 PolarHBondContact O-N 2.85Å; M565-V568 PolarHBondContact O-N 2.75Å; M565-Y569 WeakPolarHBondContact O-CD2 3.47Å; M565-Y569 PolarHBondContact O-N 3.42Å; M565-V604 HydrophobicContact CE-CG1 4.19Å; M565-I607 HydrophobicContact CE-CB 4.36Å; M565-I607 HydrophobicContact CE-CG2 4.08Å; M565-I607 HydrophobicContact SD-CB 4.48Å; M565-I607 HydrophobicContact SD-CG2 3.75Å; M565-M608 HydrophobicContact CB-CE 3.86Å; M565-M608 HydrophobicContact CB-CG 3.91Å; M565-M608 HydrophobicContact CB-SD 4.44Å; M565-M608 HydrophobicContact SD-CG 4.35Å
566W98.8Very high97.9Very high4 Ų414.4 Ų14.42%0.0157%0.071CC..Hα-helixtrans-63.6-40.2174.9-173.796.4000112.6G562 V563 L564 Y569 T570 K573 P575 L594 F595 P597 M608 W612G562-W566 PolarHBondContact O-N 2.79Å; G562-W566 VanDerWaalsContact O-N 3.12Å; V563-W566 CarbonylContact O-C 3.59Å; V563-W566 WeakPolarHBondContact O-CA 3.39Å; V563-W566 WeakPolarHBondContact O-CB 3.45Å; V563-W566 PolarHBondContact O-N 3.34Å; V563-W566 VanDerWaalsContact O-N 3.15Å; L564-W566 PolarHBondContact O-N 2.97Å; W566-Y569 PolarHBondContact O-N 3.07Å; W566-T570 HydrophobicContact CD2-CG2 3.84Å; W566-T570 HydrophobicContact CE3-CG2 4.12Å; W566-T570 HydrophobicContact CG-CG2 4.48Å; W566-T570 HydrophobicContact CH2-CG2 3.95Å; W566-T570 HydrophobicContact CZ2-CG2 3.66Å; W566-T570 HydrophobicContact CZ3-CG2 4.16Å; W566-T570 WeakPolarHBondContact O-CB 3.33Å; W566-T570 WeakPolarHBondContact O-CG2 3.49Å; W566-T570 PolarHBondContact O-N 2.9Å; W566-T570 PolarHBondContact O-OG1 3.49Å; W566-K573 HydrophobicContact CH2-CB 3.84Å; W566-K573 HydrophobicContact CZ3-CB 3.9Å; W566-P575 HydrophobicContact CE3-CB 4.45Å; W566-P575 HydrophobicContact CE3-CG 4.2Å; W566-P575 HydrophobicContact CZ3-CB 4.3Å; W566-P575 HydrophobicContact CZ3-CG 4.16Å; W566-L594 HydrophobicContact CB-CD1 3.98Å; W566-L594 HydrophobicContact CD2-CB 4.32Å; W566-L594 HydrophobicContact CD2-CD1 3.82Å; W566-L594 HydrophobicContact CD2-CD2 4.3Å; W566-L594 HydrophobicContact CD2-CG 4.36Å; W566-L594 HydrophobicContact CE3-CD1 4.17Å; W566-L594 HydrophobicContact CG-CB 4.06Å; W566-L594 HydrophobicContact CG-CD1 3.72Å; W566-L594 HydrophobicContact CG-CG 4.39Å; W566-L594 HydrophobicContact CH2-CD2 4.46Å; W566-L594 HydrophobicContact CZ2-CD2 4.16Å; W566-F595 VanDerWaalsContact CD1-O 3.27Å; W566-F595 HydrophobicContact CZ2-CD1 4.29Å; W566-F595 AromaticContact CZ2-CE1 3.58Å; W566-F595 HydrophobicContact CZ2-CE1 3.58Å; W566-F595 HydrophobicContact CZ2-CE2 4.46Å; W566-F595 AromaticContact CZ2-CZ 3.66Å; W566-F595 HydrophobicContact CZ2-CZ 3.66Å; W566-F595 PolarHBondContact NE1-O 2.94Å; W566-P597 HydrophobicContact CG-CG 4.17Å; W566-M608 HydrophobicContact CB-SD 4.23Å; W566-W612 HydrophobicContact CB-CH2 4.23Å; W566-W612 HydrophobicContact CB-CZ2 4.28Å
567E98.6Very high97.8Very high3 Ų319.3 Ų19.31%0.0149%0.094CC..Hα-helixtrans-58.7-47.1172.4-67.8-178.19700111.1A502 W541 V563 L564 Y569 T570 L571 G572 P575A502-E567 HydrophobicContact CB-CB 4.1Å; A502-E567 PolarHBondContact N-OE2 3.05Å; W541-E567 WeakPolarHBondContact CZ2-OE1 2.88Å; W541-E567 PolarHBondContact NE1-OE2 3.46Å; V563-E567 PolarHBondContact O-N 2.84Å; L564-E567 WeakPolarHBondContact O-CA 3.37Å; L564-E567 WeakPolarHBondContact O-CB 3.36Å; L564-E567 PolarHBondContact O-N 3.44Å; E567-Y569 PolarHBondContact O-N 2.75Å; E567-T570 CarbonylContact O-C 3.55Å; E567-T570 PolarHBondContact O-N 2.82Å; E567-T570 PolarHBondContact O-OG1 2.79Å; E567-L571 PolarHBondContact O-N 2.82Å; E567-L571 VanDerWaalsContact O-N 3.08Å; E567-G572 PolarHBondContact O-N 3.07Å; E567-P575 HydrophobicContact CG-CG 4.02Å
568V98.5Very high97.7Very high0 Ų029.6 Ų29.60%013%0.132CC..Hα-helixtrans-58.2-50.4178.2173.10000110.8L459 L463 L476 L564 M565 T570 L571L459-V568 HydrophobicContact CD2-CG2 3.98Å; L463-V568 HydrophobicContact CD1-CB 4.49Å; L463-V568 HydrophobicContact CD1-CG2 4.18Å; L463-V568 HydrophobicContact CD2-CG1 4.42Å; L476-V568 HydrophobicContact CB-CG1 3.88Å; L476-V568 HydrophobicContact CD2-CG1 3.82Å; L476-V568 HydrophobicContact CG-CG1 4.38Å; L476-V568 WeakPolarHBondContact O-CG1 3.27Å; L564-V568 HydrophobicContact CD2-CG2 4Å; L564-V568 WeakPolarHBondContact O-CG2 3.45Å; L564-V568 PolarHBondContact O-N 2.82Å; M565-V568 PolarHBondContact O-N 2.75Å; V568-T570 VanDerWaalsContact C-N 3.26Å; V568-T570 PolarHBondContact O-N 3.27Å; V568-L571 PolarHBondContact O-N 3.03Å; V568-L571 VanDerWaalsContact O-N 3.11Å
569Y98.3Very high97.5Very high3 Ų331.1 Ų31.11%0.01214%0.14CC..Hα-helixtrans-76.4-9.4-177.3-84.4-91.5000114.9T473 L476 L477 M565 W566 E567 P597 L599 A600 V604 M608T473-Y569 PolarHBondContact O-OH 3.26Å; L476-Y569 HydrophobicContact CB-CE1 4.31Å; L476-Y569 HydrophobicContact CB-CE2 4.23Å; L476-Y569 HydrophobicContact CD1-CD1 4.23Å; L476-Y569 HydrophobicContact CD1-CE1 4.43Å; L477-Y569 WeakPolarHBondContact CB-OH 3.39Å; M565-Y569 WeakPolarHBondContact O-CD2 3.47Å; M565-Y569 PolarHBondContact O-N 3.42Å; W566-Y569 PolarHBondContact O-N 3.07Å; E567-Y569 PolarHBondContact O-N 2.75Å; Y569-P597 WeakPolarHBondContact O-CB 3.4Å; Y569-L599 HydrophobicContact CD1-CB 4.08Å; Y569-L599 WeakPolarHBondContact CE1-O 3.37Å; Y569-A600 HydrophobicContact CD1-CB 3.63Å; Y569-A600 HydrophobicContact CE1-CB 4.18Å; Y569-A600 HydrophobicContact CG-CB 4.03Å; Y569-V604 HydrophobicContact CD1-CG1 4.34Å; Y569-V604 HydrophobicContact CD2-CG1 4.02Å; Y569-V604 HydrophobicContact CE1-CG1 3.89Å; Y569-V604 HydrophobicContact CE1-CG2 4.37Å; Y569-V604 HydrophobicContact CE2-CG1 3.55Å; Y569-V604 HydrophobicContact CG-CG1 4.38Å; Y569-V604 VanDerWaalsContact CZ-CG1 3.47Å; Y569-V604 WeakPolarHBondContact OH-CG2 3.34Å; Y569-M608 HydrophobicContact CD2-CE 3.58Å; Y569-M608 HydrophobicContact CE2-CE 4.32Å; Y569-M608 HydrophobicContact CG-CE 3.81Å
570T97.6Very high97.3Very high17 Ų1734.7 Ų34.710%0.10416%0.159CC..THydrogen-bonded Turntrans-103.85.1169.7570000113.2W566 E567 V568 G572 K573 P597W566-T570 HydrophobicContact CD2-CG2 3.84Å; W566-T570 HydrophobicContact CE3-CG2 4.12Å; W566-T570 HydrophobicContact CG-CG2 4.48Å; W566-T570 HydrophobicContact CH2-CG2 3.95Å; W566-T570 HydrophobicContact CZ2-CG2 3.66Å; W566-T570 HydrophobicContact CZ3-CG2 4.16Å; W566-T570 WeakPolarHBondContact O-CB 3.33Å; W566-T570 WeakPolarHBondContact O-CG2 3.49Å; W566-T570 PolarHBondContact O-N 2.9Å; W566-T570 PolarHBondContact O-OG1 3.49Å; E567-T570 CarbonylContact O-C 3.55Å; E567-T570 PolarHBondContact O-N 2.82Å; E567-T570 PolarHBondContact O-OG1 2.79Å; V568-T570 VanDerWaalsContact C-N 3.26Å; V568-T570 PolarHBondContact O-N 3.27Å; T570-G572 VanDerWaalsContact C-N 3.32Å; T570-G572 PolarHBondContact O-N 2.95Å; T570-K573 PolarHBondContact OG1-N 3.13Å; T570-P597 HydrophobicContact CG2-CB 3.78Å; T570-P597 HydrophobicContact CG2-CG 3.76Å
571L97.4Very high96.9Very high50 Ų5038.4 Ų38.426%0.26218%0.178SC..THydrogen-bonded Turntrans58.542.8-178-48.8179.6000112.3L463 P471 L476 E567 V568 L599L463-L571 HydrophobicContact CD2-CD2 4.43Å; P471-L571 HydrophobicContact CG-CD2 3.68Å; L476-L571 HydrophobicContact CD1-CD2 4.23Å; L476-L571 HydrophobicContact CD2-CD2 4.01Å; E567-L571 PolarHBondContact O-N 2.82Å; E567-L571 VanDerWaalsContact O-N 3.08Å; V568-L571 PolarHBondContact O-N 3.03Å; V568-L571 VanDerWaalsContact O-N 3.11Å; L571-L599 HydrophobicContact CD1-CD1 4.06Å; L571-L599 HydrophobicContact CD2-CD1 4.03Å; L571-L599 HydrophobicContact CG-CD1 3.97Å
572G96.6Very high96.5Very high1 Ų143.8 Ų43.81%0.0121%0.211CC..SBendtrans86.524.5172.700000115.4K464 E567 T570K464-G572 WeakPolarHBondContact CE-O 3.39Å; K464-G572 PolarHBondContact NZ-O 3.43Å; E567-G572 PolarHBondContact O-N 3.07Å; T570-G572 VanDerWaalsContact C-N 3.32Å; T570-G572 PolarHBondContact O-N 2.95Å
573K96.8Very high96.3Very high106 Ų10647.6 Ų47.646%0.46123%0.229SC..PPolyproline II helixtrans-63.3152.9171.7-72.6-173.3-177.4-176.10111W566 T570 P575W566-K573 HydrophobicContact CH2-CB 3.84Å; W566-K573 HydrophobicContact CZ3-CB 3.9Å; T570-K573 PolarHBondContact OG1-N 3.13Å; K573-P575 WeakPolarHBondContact O-CD 3.33Å
574L96.3Very high96.1Very high80 Ų8047.7 Ų47.742%0.41923%0.229SC..PPolyproline II helixtrans-75.2122.8175.5-175.565.2000109.6W541 Y576 E577W541-L574 HydrophobicContact CH2-CD1 4.18Å; L574-Y576 PolarHBondContact O-N 2.67Å; L574-E577 HydrophobicContact CB-CB 4.1Å; L574-E577 HydrophobicContact CD2-CB 4.5Å; L574-E577 WeakPolarHBondContact O-CB 3.45Å; L574-E577 PolarHBondContact O-N 3.37Å
575P98.1Very high95.8Very high0 Ų049.7 Ų49.70%024%0.242CC..THydrogen-bonded Turntrans-59.7132.6177.6-24.534.7000110.8R540 W541 V563 W566 E567 K573 E577 L594R540-P575 HydrophobicContact CB-CB 4.34Å; R540-P575 WeakPolarHBondContact CD-O 3.2Å; R540-P575 PolarHBondContact NH1-O 3.07Å; W541-P575 HydrophobicContact CZ2-CG 3.97Å; V563-P575 HydrophobicContact CG1-CB 3.87Å; V563-P575 HydrophobicContact CG1-CG 3.51Å; W566-P575 HydrophobicContact CE3-CB 4.45Å; W566-P575 HydrophobicContact CE3-CG 4.2Å; W566-P575 HydrophobicContact CZ3-CB 4.3Å; W566-P575 HydrophobicContact CZ3-CG 4.16Å; E567-P575 HydrophobicContact CG-CG 4.02Å; K573-P575 WeakPolarHBondContact O-CD 3.33Å; P575-E577 VanDerWaalsContact C-N 3.3Å; P575-E577 PolarHBondContact O-N 3.45Å; P575-L594 HydrophobicContact CB-CD1 4.12Å; P575-L594 HydrophobicContact CB-CD2 4.1Å
576Y97Very high95.5Very high22 Ų2252.9 Ų52.99%0.08626%0.259CS..THydrogen-bonded Turntrans55.835.9-177.7-45-77000114.4R540 L574 R578 L579 I584 V588 L592 L594R540-Y576 PolarHBondContact NH1-O 3.41Å; L574-Y576 PolarHBondContact O-N 2.67Å; Y576-R578 PolarHBondContact O-N 2.8Å; Y576-L579 PolarHBondContact O-N 3.2Å; Y576-I584 HydrophobicContact CD2-CG2 4.37Å; Y576-I584 HydrophobicContact CG-CG1 4.44Å; Y576-V588 HydrophobicContact CE1-CG2 4.36Å; Y576-V588 HydrophobicContact CE2-CG2 4.33Å; Y576-L592 HydrophobicContact CD1-CD2 3.95Å; Y576-L592 HydrophobicContact CE1-CD2 4Å; Y576-L592 HydrophobicContact CE1-CG 4.23Å; Y576-L594 HydrophobicContact CD1-CD2 3.68Å; Y576-L594 HydrophobicContact CD1-CG 4.42Å; Y576-L594 HydrophobicContact CD2-CD2 4.05Å; Y576-L594 HydrophobicContact CE1-CD2 3.55Å; Y576-L594 HydrophobicContact CE1-CG 3.79Å; Y576-L594 HydrophobicContact CE2-CD1 4.38Å; Y576-L594 HydrophobicContact CE2-CD2 3.94Å; Y576-L594 HydrophobicContact CE2-CG 4.05Å; Y576-L594 HydrophobicContact CG-CD2 3.93Å
577E94.1Very high95.4Very high109 Ų10956.2 Ų56.251%0.50927%0.274SS..THydrogen-bonded Turntrans-47.3-27.5-171.668.8-174.8-173.200116.1L574 P575L574-E577 HydrophobicContact CB-CB 4.1Å; L574-E577 HydrophobicContact CD2-CB 4.5Å; L574-E577 WeakPolarHBondContact O-CB 3.45Å; L574-E577 PolarHBondContact O-N 3.37Å; P575-E577 VanDerWaalsContact C-N 3.3Å; P575-E577 PolarHBondContact O-N 3.45Å
578R94.8Very high95.2Very high219 Ų21956.1 Ų56.183%0.82627%0.274SS*.THydrogen-bonded Turntrans-85.6-9.9-177.9-58.1-174.5-176.8-177.1-1.4114.6Y576Y576-R578 PolarHBondContact O-N 2.8Å
579L95Very high94.9Very high31 Ų3158.4 Ų58.416%0.16229%0.29CS..SBendtrans-108.5144.5-176.8-57.4-177.1000110.3R540 Y576 E583 I584 Q587 L592R540-L579 PolarHBondContact NH1-O 3.37Å; R540-L579 PolarHBondContact NH2-O 3.42Å; Y576-L579 PolarHBondContact O-N 3.2Å; L579-E583 WeakPolarHBondContact CA-OE2 3.44Å; L579-E583 HydrophobicContact CB-CB 4.14Å; L579-E583 HydrophobicContact CD2-CB 4.37Å; L579-I584 HydrophobicContact CB-CD1 4.2Å; L579-I584 HydrophobicContact CB-CG1 3.6Å; L579-I584 HydrophobicContact CD1-CG1 4.21Å; L579-Q587 HydrophobicContact CD1-CB 4.47Å; L579-L592 HydrophobicContact CD1-CD2 3.74Å
580N93Very high94.7Very high78 Ų7867.4 Ų67.442%0.41732%0.324SS..  trans-82.2169.2167.771.256.3000111.4T582 E583 I584N580-T582 VanDerWaalsContact C-N 3.28Å; N580-T582 PolarHBondContact O-N 2.82Å; N580-T582 WeakPolarHBondContact OD1-CB 3.42Å; N580-T582 PolarHBondContact OD1-N 3.29Å; N580-E583 VanDerWaalsContact CG-OE2 3.31Å; N580-E583 PolarHBondContact N-OE2 2.76Å; N580-E583 PolarHBondContact ND2-OE1 2.83Å; N580-E583 PolarHBondContact ND2-OE2 2.9Å; N580-E583 PolarHBondContact O-N 3.04Å; N580-E583 PolarHBondContact OD1-N 2.89Å; N580-I584 VanDerWaalsContact O-CG1 3.23Å; N580-I584 WeakPolarHBondContact O-CG1 3.37Å; N580-I584 PolarHBondContact O-N 2.69Å
581N90.1Very high94.6Very high83 Ų8368.4 Ų68.444%0.44434%0.337SS..Hα-helixtrans-59.9-35.3-175.2-75.41.2000113.5V539 I584 V585V539-N581 HydrophobicContact CB-CB 4.31Å; V539-N581 HydrophobicContact CG1-CB 4.01Å; V539-N581 HydrophobicContact CG2-CB 4.23Å; N581-I584 PolarHBondContact O-N 2.8Å; N581-V585 WeakPolarHBondContact O-CG2 3.45Å; N581-V585 PolarHBondContact O-N 3.38Å; N581-V585 VanDerWaalsContact O-N 3.14Å
582T91.1Very high94.6Very high113 Ų11368.9 Ų68.969%0.69334%0.34SS*.Hα-helixtrans-69.9-42.3179.2-54.20000111.3N580 I584 V585 D586N580-T582 VanDerWaalsContact C-N 3.28Å; N580-T582 PolarHBondContact O-N 2.82Å; N580-T582 WeakPolarHBondContact OD1-CB 3.42Å; N580-T582 PolarHBondContact OD1-N 3.29Å; T582-I584 VanDerWaalsContact C-N 3.31Å; T582-I584 PolarHBondContact O-N 2.92Å; T582-V585 PolarHBondContact O-N 3.19Å; T582-D586 PolarHBondContact O-N 3.49Å
583E94.6Very high94.6Very high81 Ų8171.3 Ų71.338%0.37935%0.349SS..Hα-helixtrans-64.5-36.7175.1-69.2167158.300111.9L579 N580 D586 Q587L579-E583 WeakPolarHBondContact CA-OE2 3.44Å; L579-E583 HydrophobicContact CB-CB 4.14Å; L579-E583 HydrophobicContact CD2-CB 4.37Å; N580-E583 VanDerWaalsContact CG-OE2 3.31Å; N580-E583 PolarHBondContact N-OE2 2.76Å; N580-E583 PolarHBondContact ND2-OE1 2.83Å; N580-E583 PolarHBondContact ND2-OE2 2.9Å; N580-E583 PolarHBondContact O-N 3.04Å; N580-E583 PolarHBondContact OD1-N 2.89Å; E583-D586 PolarHBondContact O-N 2.93Å; E583-Q587 WeakPolarHBondContact O-CB 3.21Å; E583-Q587 WeakPolarHBondContact O-CG 3.5Å; E583-Q587 PolarHBondContact O-N 3.17Å
584I93.9Very high94.7Very high1 Ų166.5 Ų66.51%0.00533%0.328CS..Hα-helixtrans-64.3-44.7177-68.7166.6000110.6V539 R540 Y576 L579 N580 N581 T582 D586 Q587 V588V539-I584 HydrophobicContact CG1-CB 4.29Å; V539-I584 HydrophobicContact CG1-CG2 4.03Å; R540-I584 HydrophobicContact CG-CD1 3.83Å; Y576-I584 HydrophobicContact CD2-CG2 4.37Å; Y576-I584 HydrophobicContact CG-CG1 4.44Å; L579-I584 HydrophobicContact CB-CD1 4.2Å; L579-I584 HydrophobicContact CB-CG1 3.6Å; L579-I584 HydrophobicContact CD1-CG1 4.21Å; N580-I584 VanDerWaalsContact O-CG1 3.23Å; N580-I584 WeakPolarHBondContact O-CG1 3.37Å; N580-I584 PolarHBondContact O-N 2.69Å; N581-I584 PolarHBondContact O-N 2.8Å; T582-I584 VanDerWaalsContact C-N 3.31Å; T582-I584 PolarHBondContact O-N 2.92Å; I584-D586 VanDerWaalsContact C-N 3.33Å; I584-D586 PolarHBondContact O-N 3.12Å; I584-Q587 PolarHBondContact O-N 2.81Å; I584-V588 HydrophobicContact CG2-CG2 3.85Å; I584-V588 WeakPolarHBondContact O-CB 3.49Å; I584-V588 VanDerWaalsContact O-CG2 3.27Å; I584-V588 WeakPolarHBondContact O-CG2 3.4Å; I584-V588 PolarHBondContact O-N 3.09Å
585V92.4Very high94.8Very high42 Ų4268.6 Ų68.626%0.25533%0.334SS..Hα-helixtrans-56.1-49.9176.2173.80000110.4V539 L547 L548 N581 T582 S589V539-V585 HydrophobicContact CG1-CG2 4.14Å; L547-V585 HydrophobicContact CB-CG1 4.46Å; L547-V585 HydrophobicContact CB-CG2 4.43Å; L547-V585 HydrophobicContact CD1-CG2 4.41Å; L547-V585 HydrophobicContact CD2-CG2 4.14Å; L548-V585 HydrophobicContact CD2-CG1 4.44Å; N581-V585 WeakPolarHBondContact O-CG2 3.45Å; N581-V585 PolarHBondContact O-N 3.38Å; N581-V585 VanDerWaalsContact O-N 3.14Å; T582-V585 PolarHBondContact O-N 3.19Å; V585-S589 VanDerWaalsContact O-CB 3.28Å; V585-S589 WeakPolarHBondContact O-CB 3.26Å; V585-S589 PolarHBondContact O-N 2.9Å; V585-S589 PolarHBondContact O-OG 3.24Å
586D93.3Very high94.8Very high68 Ų6873.2 Ų73.236%0.36435%0.352SS..Hα-helixtrans-64.5-49.1179.4-179.665.9000112.7T582 E583 I584 S589 R590T582-D586 PolarHBondContact O-N 3.49Å; E583-D586 PolarHBondContact O-N 2.93Å; I584-D586 VanDerWaalsContact C-N 3.33Å; I584-D586 PolarHBondContact O-N 3.12Å; D586-S589 PolarHBondContact O-N 3.24Å; D586-R590 VanDerWaalsContact CG-NH2 3.29Å; D586-R590 VanDerWaalsContact O-CG 3.32Å; D586-R590 WeakPolarHBondContact O-CG 3.24Å; D586-R590 PolarHBondContact O-N 3.49Å; D586-R590 VanDerWaalsContact O-N 3.16Å; D586-R590 IonicContact OD1-CZ 3.46Å; D586-R590 IonicContact OD1-NE 2.81Å; D586-R590 PolarHBondContact OD1-NE 2.86Å; D586-R590 IonicContact OD1-NH2 2.93Å; D586-R590 PolarHBondContact OD1-NH2 2.86Å; D586-R590 IonicContact OD2-CZ 2.9Å; D586-R590 IonicContact OD2-NE 3.89Å; D586-R590 PolarHBondContact OD2-NE 2.91Å; D586-R590 VanDerWaalsContact OD2-NE 3.15Å; D586-R590 IonicContact OD2-NH1 2.63Å; D586-R590 IonicContact OD2-NH2 3.13Å; D586-R590 PolarHBondContact OD2-NH2 3.01Å
587Q96.1Very high94.8Very high73 Ų7372.2 Ų72.234%0.34135%0.348SS..Hα-helixtrans-73-39.2-173.3-68.6-16443.200113.1L579 E583 I584 S589 R590 G591 L592L579-Q587 HydrophobicContact CD1-CB 4.47Å; E583-Q587 WeakPolarHBondContact O-CB 3.21Å; E583-Q587 WeakPolarHBondContact O-CG 3.5Å; E583-Q587 PolarHBondContact O-N 3.17Å; I584-Q587 PolarHBondContact O-N 2.81Å; Q587-S589 VanDerWaalsContact C-N 3.32Å; Q587-S589 PolarHBondContact O-N 2.88Å; Q587-R590 CarbonylContact O-C 3.56Å; Q587-R590 PolarHBondContact O-N 3.25Å; Q587-R590 VanDerWaalsContact O-N 3.09Å; Q587-G591 PolarHBondContact O-N 3.42Å; Q587-L592 HydrophobicContact CB-CB 3.93Å; Q587-L592 HydrophobicContact CB-CD2 3.73Å; Q587-L592 HydrophobicContact CB-CG 4.45Å; Q587-L592 WeakPolarHBondContact O-CB 3.4Å; Q587-L592 PolarHBondContact O-N 3.22Å
588V95.3Very high94.9Very high2 Ų276.2 Ų76.21%0.01237%0.366CS..Hα-helixtrans-65.1-39.7176.3172.70000110.3P544 L547 W559 Y576 I584 R590 G591 R593P544-V588 HydrophobicContact CG-CG1 4.15Å; L547-V588 HydrophobicContact CD1-CB 4.38Å; L547-V588 HydrophobicContact CD1-CG1 4.28Å; W559-V588 HydrophobicContact CH2-CG1 3.9Å; W559-V588 HydrophobicContact CZ2-CG1 3.64Å; Y576-V588 HydrophobicContact CE1-CG2 4.36Å; Y576-V588 HydrophobicContact CE2-CG2 4.33Å; I584-V588 HydrophobicContact CG2-CG2 3.85Å; I584-V588 WeakPolarHBondContact O-CB 3.49Å; I584-V588 VanDerWaalsContact O-CG2 3.27Å; I584-V588 WeakPolarHBondContact O-CG2 3.4Å; I584-V588 PolarHBondContact O-N 3.09Å; V588-R590 PolarHBondContact O-N 2.96Å; V588-G591 PolarHBondContact O-N 2.72Å; V588-R593 PolarHBondContact O-NH1 3.01Å
589S91.6Very high95Very high48 Ų4869 Ų6934%0.33634%0.344SS..Hα-helixtrans-64.7-20.2172.9-67.90000114V585 D586 Q587V585-S589 VanDerWaalsContact O-CB 3.28Å; V585-S589 WeakPolarHBondContact O-CB 3.26Å; V585-S589 PolarHBondContact O-N 2.9Å; V585-S589 PolarHBondContact O-OG 3.24Å; D586-S589 PolarHBondContact O-N 3.24Å; Q587-S589 VanDerWaalsContact C-N 3.32Å; Q587-S589 PolarHBondContact O-N 2.88Å
590R94.1Very high95Very high192 Ų19267.6 Ų67.673%0.72534%0.337SS*.THydrogen-bonded Turntrans-92.55.8173.2-68.1175.5-167.3-164.46.9113.7D586 Q587 V588D586-R590 VanDerWaalsContact CG-NH2 3.29Å; D586-R590 VanDerWaalsContact O-CG 3.32Å; D586-R590 WeakPolarHBondContact O-CG 3.24Å; D586-R590 PolarHBondContact O-N 3.49Å; D586-R590 VanDerWaalsContact O-N 3.16Å; D586-R590 IonicContact OD1-CZ 3.46Å; D586-R590 IonicContact OD1-NE 2.81Å; D586-R590 PolarHBondContact OD1-NE 2.86Å; D586-R590 IonicContact OD1-NH2 2.93Å; D586-R590 PolarHBondContact OD1-NH2 2.86Å; D586-R590 IonicContact OD2-CZ 2.9Å; D586-R590 IonicContact OD2-NE 3.89Å; D586-R590 PolarHBondContact OD2-NE 2.91Å; D586-R590 VanDerWaalsContact OD2-NE 3.15Å; D586-R590 IonicContact OD2-NH1 2.63Å; D586-R590 IonicContact OD2-NH2 3.13Å; D586-R590 PolarHBondContact OD2-NH2 3.01Å; Q587-R590 CarbonylContact O-C 3.56Å; Q587-R590 PolarHBondContact O-N 3.25Å; Q587-R590 VanDerWaalsContact O-N 3.09Å; V588-R590 PolarHBondContact O-N 2.96Å
591G95.1Very high95.1Very high37 Ų3766.6 Ų66.638%0.38133%0.331SS..THydrogen-bonded Turntrans97.38177.100000115.1Q587 V588 R593Q587-G591 PolarHBondContact O-N 3.42Å; V588-G591 PolarHBondContact O-N 2.72Å; G591-R593 PolarHBondContact O-N 3.48Å
592L97.1Very high95.5Very high61 Ų6168.3 Ų68.332%0.31934%0.337SS..  trans-60.5135.2171.6-17870.9000109.9Y576 L579 Q587Y576-L592 HydrophobicContact CD1-CD2 3.95Å; Y576-L592 HydrophobicContact CE1-CD2 4Å; Y576-L592 HydrophobicContact CE1-CG 4.23Å; L579-L592 HydrophobicContact CD1-CD2 3.74Å; Q587-L592 HydrophobicContact CB-CB 3.93Å; Q587-L592 HydrophobicContact CB-CD2 3.73Å; Q587-L592 HydrophobicContact CB-CG 4.45Å; Q587-L592 WeakPolarHBondContact O-CB 3.4Å; Q587-L592 PolarHBondContact O-N 3.22Å
593R97.7Very high95.7Very high52 Ų5268.2 Ų68.220%0.19633%0.327CS..  trans-130.3158.5173.1-61.3-60.4-177.9-91.1-1110.4V588 G591 W612 D614V588-R593 PolarHBondContact O-NH1 3.01Å; G591-R593 PolarHBondContact O-N 3.48Å; R593-W612 HydrophobicContact CB-CE3 4.21Å; R593-W612 PolarHBondContact NE-O 3.12Å; R593-W612 PolarHBondContact NH2-O 3.14Å; R593-D614 IonicContact CZ-OD1 3.13Å; R593-D614 IonicContact NH1-OD1 2.79Å; R593-D614 VanDerWaalsContact NH2-CG 3.28Å; R593-D614 IonicContact NH2-OD1 3.24Å; R593-D614 PolarHBondContact NH2-OD1 2.97Å; R593-D614 IonicContact NH2-OD2 3.97Å
594L98.3Very high95.9Very high5 Ų564.4 Ų64.43%0.02631%0.309CS..PPolyproline II helixtrans-65.7142.9175-67165.2000110V563 W566 P575 Y576 Y605 W612V563-L594 HydrophobicContact CB-CD1 4.49Å; V563-L594 HydrophobicContact CG1-CD1 4.09Å; V563-L594 HydrophobicContact CG2-CD1 4.23Å; W566-L594 HydrophobicContact CB-CD1 3.98Å; W566-L594 HydrophobicContact CD2-CB 4.32Å; W566-L594 HydrophobicContact CD2-CD1 3.82Å; W566-L594 HydrophobicContact CD2-CD2 4.3Å; W566-L594 HydrophobicContact CD2-CG 4.36Å; W566-L594 HydrophobicContact CE3-CD1 4.17Å; W566-L594 HydrophobicContact CG-CB 4.06Å; W566-L594 HydrophobicContact CG-CD1 3.72Å; W566-L594 HydrophobicContact CG-CG 4.39Å; W566-L594 HydrophobicContact CH2-CD2 4.46Å; W566-L594 HydrophobicContact CZ2-CD2 4.16Å; P575-L594 HydrophobicContact CB-CD1 4.12Å; P575-L594 HydrophobicContact CB-CD2 4.1Å; Y576-L594 HydrophobicContact CD1-CD2 3.68Å; Y576-L594 HydrophobicContact CD1-CG 4.42Å; Y576-L594 HydrophobicContact CD2-CD2 4.05Å; Y576-L594 HydrophobicContact CE1-CD2 3.55Å; Y576-L594 HydrophobicContact CE1-CG 3.79Å; Y576-L594 HydrophobicContact CE2-CD1 4.38Å; Y576-L594 HydrophobicContact CE2-CD2 3.94Å; Y576-L594 HydrophobicContact CE2-CG 4.05Å; Y576-L594 HydrophobicContact CG-CD2 3.93Å; L594-Y605 PolarHBondContact O-OH 2.91Å; L594-W612 HydrophobicContact CB-CH2 3.7Å; L594-W612 HydrophobicContact CB-CZ2 4.31Å; L594-W612 HydrophobicContact CB-CZ3 4.08Å; L594-W612 HydrophobicContact CD1-CH2 4.06Å; L594-W612 HydrophobicContact CD1-CZ2 3.84Å; L594-W612 HydrophobicContact CG-CH2 4.39Å
595F97.8Very high96.1Very high123 Ų12366.5 Ų66.554%0.53932%0.317SS..PPolyproline II helixtrans-73160.2178.966.6-91.8000111.9W566 P597W566-F595 VanDerWaalsContact CD1-O 3.27Å; W566-F595 HydrophobicContact CZ2-CD1 4.29Å; W566-F595 AromaticContact CZ2-CE1 3.58Å; W566-F595 HydrophobicContact CZ2-CE1 3.58Å; W566-F595 HydrophobicContact CZ2-CE2 4.46Å; W566-F595 AromaticContact CZ2-CZ 3.66Å; W566-F595 HydrophobicContact CZ2-CZ 3.66Å; W566-F595 PolarHBondContact NE1-O 2.94Å; F595-P597 VanDerWaalsContact O-CD 3.28Å; F595-P597 WeakPolarHBondContact O-CD 3.46Å
596R98.4Very high96.4Very high97 Ų9768 Ų6837%0.36633%0.329SS..PPolyproline II helixtrans-65118.7175-175.8165.569.171.3-5112.3A600 E602 Y605R596-A600 HydrophobicContact CG-CB 4.33Å; R596-A600 PolarHBondContact NH1-O 3Å; R596-E602 IonicContact CZ-OE1 3.45Å; R596-E602 IonicContact NE-OE1 3.8Å; R596-E602 PolarHBondContact NE-OE1 3.46Å; R596-E602 IonicContact NE-OE2 2.91Å; R596-E602 IonicContact NH2-OE1 2.94Å; R596-E602 PolarHBondContact NH2-OE1 3.38Å; R596-Y605 HydrophobicContact CB-CD1 3.8Å; R596-Y605 HydrophobicContact CB-CD2 3.67Å; R596-Y605 HydrophobicContact CB-CE1 3.92Å; R596-Y605 HydrophobicContact CB-CE2 3.79Å; R596-Y605 HydrophobicContact CB-CG 3.66Å; R596-Y605 VanDerWaalsContact CD-CB 3.46Å; R596-Y605 HydrophobicContact CG-CD1 4.03Å; R596-Y605 HydrophobicContact CG-CD2 3.82Å; R596-Y605 HydrophobicContact CG-CE2 4.45Å; R596-Y605 HydrophobicContact CG-CG 3.57Å
597P97.6Very high96.6Very high1 Ų165.5 Ų65.51%0.00632%0.316CS..PPolyproline II helixtrans-60.6149.5173.9-23.535000112.4W566 Y569 T570 F595 L599 A600 M608W566-P597 HydrophobicContact CG-CG 4.17Å; Y569-P597 WeakPolarHBondContact O-CB 3.4Å; T570-P597 HydrophobicContact CG2-CB 3.78Å; T570-P597 HydrophobicContact CG2-CG 3.76Å; F595-P597 VanDerWaalsContact O-CD 3.28Å; F595-P597 WeakPolarHBondContact O-CD 3.46Å; P597-L599 VanDerWaalsContact C-N 3.27Å; P597-L599 PolarHBondContact O-N 3.46Å; P597-A600 HydrophobicContact CB-CB 4.08Å; P597-A600 HydrophobicContact CG-CB 4.25Å; P597-A600 PolarHBondContact O-N 3.37Å; P597-M608 HydrophobicContact CG-CE 4.49Å
598Q95.9Very high96.7Very high193 Ų19362 Ų6290%0.90230%0.299SS*.THydrogen-bonded Turntrans-61.6-34.9179.6-71.5-179.3-15.200113A600Q598-A600 VanDerWaalsContact C-N 3.27Å; Q598-A600 PolarHBondContact O-N 3.38Å
599L95.9Very high96.9Very high68 Ų6864.5 Ų64.536%0.35632%0.315SS..THydrogen-bonded Turntrans-77.5-12.2178.3-61.2176000112.9T473 L476 Y569 L571 P597T473-L599 WeakPolarHBondContact CG2-O 3.09Å; L476-L599 HydrophobicContact CD1-CB 4.38Å; L476-L599 HydrophobicContact CD1-CD1 3.95Å; Y569-L599 HydrophobicContact CD1-CB 4.08Å; Y569-L599 WeakPolarHBondContact CE1-O 3.37Å; L571-L599 HydrophobicContact CD1-CD1 4.06Å; L571-L599 HydrophobicContact CD2-CD1 4.03Å; L571-L599 HydrophobicContact CG-CD1 3.97Å; P597-L599 VanDerWaalsContact C-N 3.27Å; P597-L599 PolarHBondContact O-N 3.46Å
600A96.9Very high97.2Very high1 Ų164.3 Ų64.31%0.00831%0.314CS..  trans-93.8124.7-179.300000110.3Y569 R596 P597 Q598 V604 M608Y569-A600 HydrophobicContact CD1-CB 3.63Å; Y569-A600 HydrophobicContact CE1-CB 4.18Å; Y569-A600 HydrophobicContact CG-CB 4.03Å; R596-A600 HydrophobicContact CG-CB 4.33Å; R596-A600 PolarHBondContact NH1-O 3Å; P597-A600 HydrophobicContact CB-CB 4.08Å; P597-A600 HydrophobicContact CG-CB 4.25Å; P597-A600 PolarHBondContact O-N 3.37Å; Q598-A600 VanDerWaalsContact C-N 3.27Å; Q598-A600 PolarHBondContact O-N 3.38Å; A600-V604 HydrophobicContact CB-CB 4.32Å; A600-V604 HydrophobicContact CB-CG1 4.01Å; A600-M608 HydrophobicContact CB-CE 4.22Å
601N95.1Very high97.4Very high57 Ų5755.2 Ų55.231%0.30528%0.279SS..  trans-74.7173168.571.428.5000110.9K603 V604 Y605N601-K603 VanDerWaalsContact C-N 3.29Å; N601-K603 PolarHBondContact O-N 3.49Å; N601-K603 WeakPolarHBondContact OD1-CB 3.29Å; N601-K603 PolarHBondContact OD1-N 3.4Å; N601-V604 PolarHBondContact O-N 3.47Å; N601-V604 WeakPolarHBondContact OD1-CG2 3.46Å; N601-V604 PolarHBondContact OD1-N 2.77Å; N601-Y605 WeakPolarHBondContact O-CB 3.42Å; N601-Y605 PolarHBondContact O-N 2.83Å
602E96.7Very high97.6Very high119 Ų11953.7 Ų53.756%0.55626%0.262SS*.Hα-helixtrans-62.2-34.5-178.4-65.2-60.3154.100112.8R596 Y605 S606R596-E602 IonicContact CZ-OE1 3.45Å; R596-E602 IonicContact NE-OE1 3.8Å; R596-E602 PolarHBondContact NE-OE1 3.46Å; R596-E602 IonicContact NE-OE2 2.91Å; R596-E602 IonicContact NH2-OE1 2.94Å; R596-E602 PolarHBondContact NH2-OE1 3.38Å; E602-Y605 PolarHBondContact O-N 2.91Å; E602-S606 WeakPolarHBondContact O-CB 3.41Å; E602-S606 PolarHBondContact O-N 3.18Å
603K96.8Very high97.6Very high111 Ų11152 Ų5248%0.48326%0.255SS..Hα-helixtrans-66.3-46.6178.2-64.4-169.1179.5-1700111.6N601 Y605 S606 I607 L632 E635N601-K603 VanDerWaalsContact C-N 3.29Å; N601-K603 PolarHBondContact O-N 3.49Å; N601-K603 WeakPolarHBondContact OD1-CB 3.29Å; N601-K603 PolarHBondContact OD1-N 3.4Å; K603-Y605 VanDerWaalsContact C-N 3.34Å; K603-Y605 PolarHBondContact O-N 3.13Å; K603-S606 WeakPolarHBondContact O-CB 3.05Å; K603-S606 PolarHBondContact O-N 3.16Å; K603-I607 PolarHBondContact O-N 2.93Å; K603-L632 HydrophobicContact CB-CD1 3.79Å; K603-L632 HydrophobicContact CB-CD2 4.01Å; K603-L632 HydrophobicContact CD-CD1 3.57Å; K603-L632 HydrophobicContact CG-CD1 4.34Å; K603-E635 IonicContact NZ-OE1 2.65Å; K603-E635 PolarHBondContact NZ-OE1 3.38Å; K603-E635 IonicContact NZ-OE2 3.19Å; K603-E635 PolarHBondContact NZ-OE2 3.34Å
604V97.6Very high97.4Very high1 Ų154 Ų541%0.00627%0.27CS..Hα-helixtrans-60.3-46.3175.1173.20000110.3L477 M565 Y569 A600 N601 S606 I607 M608 L632L477-V604 HydrophobicContact CD1-CG2 4.38Å; M565-V604 HydrophobicContact CE-CG1 4.19Å; Y569-V604 HydrophobicContact CD1-CG1 4.34Å; Y569-V604 HydrophobicContact CD2-CG1 4.02Å; Y569-V604 HydrophobicContact CE1-CG1 3.89Å; Y569-V604 HydrophobicContact CE1-CG2 4.37Å; Y569-V604 HydrophobicContact CE2-CG1 3.55Å; Y569-V604 HydrophobicContact CG-CG1 4.38Å; Y569-V604 VanDerWaalsContact CZ-CG1 3.47Å; Y569-V604 WeakPolarHBondContact OH-CG2 3.34Å; A600-V604 HydrophobicContact CB-CB 4.32Å; A600-V604 HydrophobicContact CB-CG1 4.01Å; N601-V604 PolarHBondContact O-N 3.47Å; N601-V604 WeakPolarHBondContact OD1-CG2 3.46Å; N601-V604 PolarHBondContact OD1-N 2.77Å; V604-S606 VanDerWaalsContact C-N 3.3Å; V604-S606 PolarHBondContact O-N 3.45Å; V604-I607 WeakPolarHBondContact O-CB 3.36Å; V604-I607 PolarHBondContact O-N 3.28Å; V604-M608 HydrophobicContact CG1-CE 3.63Å; V604-M608 PolarHBondContact O-N 3.2Å; V604-L632 HydrophobicContact CG2-CD2 3.71Å
605Y98.3Very high97.3Very high46 Ų4660 Ų6018%0.1830%0.296CS..Hα-helixtrans-66.7-33.4-179.8-173.6-116.4000112.5L594 R596 N601 E602 K603 I607 M608 T609 W612L594-Y605 PolarHBondContact O-OH 2.91Å; R596-Y605 HydrophobicContact CB-CD1 3.8Å; R596-Y605 HydrophobicContact CB-CD2 3.67Å; R596-Y605 HydrophobicContact CB-CE1 3.92Å; R596-Y605 HydrophobicContact CB-CE2 3.79Å; R596-Y605 HydrophobicContact CB-CG 3.66Å; R596-Y605 VanDerWaalsContact CD-CB 3.46Å; R596-Y605 HydrophobicContact CG-CD1 4.03Å; R596-Y605 HydrophobicContact CG-CD2 3.82Å; R596-Y605 HydrophobicContact CG-CE2 4.45Å; R596-Y605 HydrophobicContact CG-CG 3.57Å; N601-Y605 WeakPolarHBondContact O-CB 3.42Å; N601-Y605 PolarHBondContact O-N 2.83Å; E602-Y605 PolarHBondContact O-N 2.91Å; K603-Y605 VanDerWaalsContact C-N 3.34Å; K603-Y605 PolarHBondContact O-N 3.13Å; Y605-I607 VanDerWaalsContact C-N 3.25Å; Y605-I607 PolarHBondContact O-N 3.24Å; Y605-M608 HydrophobicContact CD2-CB 4.33Å; Y605-M608 HydrophobicContact CD2-SD 3.97Å; Y605-M608 WeakPolarHBondContact O-CB 3.34Å; Y605-M608 PolarHBondContact O-N 3.19Å; Y605-T609 HydrophobicContact CD1-CG2 4.02Å; Y605-T609 HydrophobicContact CD2-CG2 4.46Å; Y605-T609 HydrophobicContact CE1-CG2 3.6Å; Y605-T609 HydrophobicContact CE2-CG2 4.08Å; Y605-T609 HydrophobicContact CG-CG2 4.44Å; Y605-T609 WeakPolarHBondContact O-CG2 3.37Å; Y605-T609 PolarHBondContact O-N 3.47Å; Y605-T609 PolarHBondContact O-OG1 2.82Å; Y605-W612 HydrophobicContact CE2-CZ3 4.17Å
606S98.3Very high97.1Very high72 Ų7255.3 Ų55.350%0.50328%0.28SS..Hα-helixtrans-57-40.3172.4-171.20000111.7E602 K603 V604 T609 S610E602-S606 WeakPolarHBondContact O-CB 3.41Å; E602-S606 PolarHBondContact O-N 3.18Å; K603-S606 WeakPolarHBondContact O-CB 3.05Å; K603-S606 PolarHBondContact O-N 3.16Å; V604-S606 VanDerWaalsContact C-N 3.3Å; V604-S606 PolarHBondContact O-N 3.45Å; S606-T609 WeakPolarHBondContact CA-OG1 3.47Å; S606-T609 PolarHBondContact O-N 2.92Å; S606-T609 PolarHBondContact O-OG1 3.26Å; S606-S610 PolarHBondContact O-N 2.97Å
607I98.4Very high97Very high16 Ų1657.7 Ų57.78%0.08230%0.3CS..Hα-helixtrans-64-43.8174.5-59.6171000110.5M565 K603 V604 Y605 T609 S610 C611 L625 V629 L632M565-I607 HydrophobicContact CE-CB 4.36Å; M565-I607 HydrophobicContact CE-CG2 4.08Å; M565-I607 HydrophobicContact SD-CB 4.48Å; M565-I607 HydrophobicContact SD-CG2 3.75Å; K603-I607 PolarHBondContact O-N 2.93Å; V604-I607 WeakPolarHBondContact O-CB 3.36Å; V604-I607 PolarHBondContact O-N 3.28Å; Y605-I607 VanDerWaalsContact C-N 3.25Å; Y605-I607 PolarHBondContact O-N 3.24Å; I607-T609 VanDerWaalsContact C-N 3.33Å; I607-T609 PolarHBondContact O-N 3.34Å; I607-S610 PolarHBondContact O-N 3.08Å; I607-S610 PolarHBondContact O-OG 2.9Å; I607-C611 PolarHBondContact O-N 3.11Å; I607-C611 PolarHBondContact O-SG 3.12Å; I607-L625 HydrophobicContact CG2-CD2 3.66Å; I607-V629 HydrophobicContact CD1-CG2 4.09Å; I607-L632 HydrophobicContact CD1-CD2 3.89Å
608M98.6Very high96.9Very high0 Ų063 Ų630%032%0.324CS..Hα-helixtrans-60.3-44.7176.3-58.2178.4-174.100111.3M565 W566 Y569 P597 A600 V604 Y605 C611 W612M565-M608 HydrophobicContact CB-CE 3.86Å; M565-M608 HydrophobicContact CB-CG 3.91Å; M565-M608 HydrophobicContact CB-SD 4.44Å; M565-M608 HydrophobicContact SD-CG 4.35Å; W566-M608 HydrophobicContact CB-SD 4.23Å; Y569-M608 HydrophobicContact CD2-CE 3.58Å; Y569-M608 HydrophobicContact CE2-CE 4.32Å; Y569-M608 HydrophobicContact CG-CE 3.81Å; P597-M608 HydrophobicContact CG-CE 4.49Å; A600-M608 HydrophobicContact CB-CE 4.22Å; V604-M608 HydrophobicContact CG1-CE 3.63Å; V604-M608 PolarHBondContact O-N 3.2Å; Y605-M608 HydrophobicContact CD2-CB 4.33Å; Y605-M608 HydrophobicContact CD2-SD 3.97Å; Y605-M608 WeakPolarHBondContact O-CB 3.34Å; Y605-M608 PolarHBondContact O-N 3.19Å; M608-C611 WeakPolarHBondContact O-CB 3.36Å; M608-C611 PolarHBondContact O-N 2.99Å; M608-W612 HydrophobicContact CB-CH2 3.75Å; M608-W612 HydrophobicContact CB-CZ2 4.19Å; M608-W612 HydrophobicContact CB-CZ3 3.96Å; M608-W612 VanDerWaalsContact O-CD2 3.25Å; M608-W612 PolarHBondContact O-N 3.47Å
609T98.2Very high97.1Very high54 Ų5454 Ų5433%0.33128%0.282SS..Hα-helixtrans-70.2-32-178.454.50000113.5Y605 S606 I607 C611 W612Y605-T609 HydrophobicContact CD1-CG2 4.02Å; Y605-T609 HydrophobicContact CD2-CG2 4.46Å; Y605-T609 HydrophobicContact CE1-CG2 3.6Å; Y605-T609 HydrophobicContact CE2-CG2 4.08Å; Y605-T609 HydrophobicContact CG-CG2 4.44Å; Y605-T609 WeakPolarHBondContact O-CG2 3.37Å; Y605-T609 PolarHBondContact O-N 3.47Å; Y605-T609 PolarHBondContact O-OG1 2.82Å; S606-T609 WeakPolarHBondContact CA-OG1 3.47Å; S606-T609 PolarHBondContact O-N 2.92Å; S606-T609 PolarHBondContact O-OG1 3.26Å; I607-T609 VanDerWaalsContact C-N 3.33Å; I607-T609 PolarHBondContact O-N 3.34Å; T609-C611 VanDerWaalsContact C-N 3.26Å; T609-C611 PolarHBondContact O-N 2.97Å; T609-W612 HydrophobicContact CG2-CE3 4.38Å; T609-W612 HydrophobicContact CG2-CZ3 4.47Å; T609-W612 PolarHBondContact O-N 2.98Å
610S98.4Very high97.2Very high45 Ų4551.6 Ų51.632%0.31527%0.271SS..Hα-helixtrans-66.5-31174.768.80000111.9S606 I607 W612 P620S606-S610 PolarHBondContact O-N 2.97Å; I607-S610 PolarHBondContact O-N 3.08Å; I607-S610 PolarHBondContact O-OG 2.9Å; S610-W612 PolarHBondContact O-N 3.49Å; S610-P620 WeakPolarHBondContact O-CD 3.38Å
611C98.8Very high97.2Very high0 Ų053.5 Ų53.50%028%0.282CS..Hα-helixtrans-66.3-23.8172.1-61.60000113I558 W559 I607 M608 T609 R619I558-C611 HydrophobicContact CG2-CB 4.06Å; I558-C611 WeakPolarHBondContact O-CB 3.5Å; W559-C611 WeakPolarHBondContact CA-O 3.37Å; I607-C611 PolarHBondContact O-N 3.11Å; I607-C611 PolarHBondContact O-SG 3.12Å; M608-C611 WeakPolarHBondContact O-CB 3.36Å; M608-C611 PolarHBondContact O-N 2.99Å; T609-C611 VanDerWaalsContact C-N 3.26Å; T609-C611 PolarHBondContact O-N 2.97Å; C611-R619 VanDerWaalsContact O-CD 3.3Å; C611-R619 WeakPolarHBondContact O-CD 3.33Å
612W98.4Very high97.4Very high5 Ų550.9 Ų50.92%0.01927%0.268CS..THydrogen-bonded Turntrans-104.526.4-175.5-52.7-39.4000114.6W559 G562 V563 W566 R593 L594 Y605 M608 T609 S610 D614W559-W612 HydrophobicContact CD2-CB 4.46Å; W559-W612 AromaticContact CD2-CD1 3.63Å; W559-W612 HydrophobicContact CD2-CG 4.39Å; W559-W612 AromaticContact CE2-CD1 3.79Å; W559-W612 HydrophobicContact CE3-CB 4.03Å; W559-W612 HydrophobicContact CE3-CG 4.43Å; W559-W612 AromaticContact CG-CD1 3.9Å; W559-W612 HydrophobicContact CH2-CB 4.16Å; W559-W612 HydrophobicContact CZ3-CB 3.88Å; W559-W612 WeakPolarHBondContact CZ3-O 3.39Å; W559-W612 PolarHBondContact O-NE1 3.37Å; G562-W612 VanDerWaalsContact O-CZ2 3.23Å; G562-W612 WeakPolarHBondContact O-CZ2 3.29Å; V563-W612 HydrophobicContact CG2-CZ2 4.33Å; W566-W612 HydrophobicContact CB-CH2 4.23Å; W566-W612 HydrophobicContact CB-CZ2 4.28Å; R593-W612 HydrophobicContact CB-CE3 4.21Å; R593-W612 PolarHBondContact NE-O 3.12Å; R593-W612 PolarHBondContact NH2-O 3.14Å; L594-W612 HydrophobicContact CB-CH2 3.7Å; L594-W612 HydrophobicContact CB-CZ2 4.31Å; L594-W612 HydrophobicContact CB-CZ3 4.08Å; L594-W612 HydrophobicContact CD1-CH2 4.06Å; L594-W612 HydrophobicContact CD1-CZ2 3.84Å; L594-W612 HydrophobicContact CG-CH2 4.39Å; Y605-W612 HydrophobicContact CE2-CZ3 4.17Å; M608-W612 HydrophobicContact CB-CH2 3.75Å; M608-W612 HydrophobicContact CB-CZ2 4.19Å; M608-W612 HydrophobicContact CB-CZ3 3.96Å; M608-W612 VanDerWaalsContact O-CD2 3.25Å; M608-W612 PolarHBondContact O-N 3.47Å; T609-W612 HydrophobicContact CG2-CE3 4.38Å; T609-W612 HydrophobicContact CG2-CZ3 4.47Å; T609-W612 PolarHBondContact O-N 2.98Å; S610-W612 PolarHBondContact O-N 3.49Å; W612-D614 PolarHBondContact O-N 3.27Å
613S97.8Very high97.3Very high26 Ų2650.4 Ų50.418%0.18227%0.266CS..  trans-59.1139.3169.1-173.50000110.7K615 E618 R619S613-K615 VanDerWaalsContact C-N 3.27Å; S613-K615 PolarHBondContact O-N 2.95Å; S613-E618 PolarHBondContact OG-OE2 3.49Å; S613-R619 PolarHBondContact O-NE 2.95Å; S613-R619 PolarHBondContact O-NH2 2.92Å
614D93.5Very high97.4Very high95 Ų9549.8 Ų49.851%0.50827%0.265SS..SBendtrans-60.5-38.4177-73.9-54.8000111.4R593 W612R593-D614 IonicContact CZ-OD1 3.13Å; R593-D614 IonicContact NH1-OD1 2.79Å; R593-D614 VanDerWaalsContact NH2-CG 3.28Å; R593-D614 IonicContact NH2-OD1 3.24Å; R593-D614 PolarHBondContact NH2-OD1 2.97Å; R593-D614 IonicContact NH2-OD2 3.97Å; W612-D614 PolarHBondContact O-N 3.27Å
615K95.1Very high97.4Very high131 Ų13149.7 Ų49.757%0.5726%0.264SS*.SBendtrans-86124.3174.6-59.2-165.3-153.7135.90109.9S613 D617 E618S613-K615 VanDerWaalsContact C-N 3.27Å; S613-K615 PolarHBondContact O-N 2.95Å; K615-D617 VanDerWaalsContact C-N 3.27Å; K615-D617 PolarHBondContact O-N 3.36Å; K615-E618 HydrophobicContact CB-CB 4.25Å; K615-E618 HydrophobicContact CB-CG 3.91Å; K615-E618 HydrophobicContact CD-CG 4.43Å; K615-E618 VanDerWaalsContact CD-OE1 3.32Å; K615-E618 WeakPolarHBondContact CD-OE1 3.3Å; K615-E618 WeakPolarHBondContact CE-OE1 3.26Å; K615-E618 IonicContact NZ-OE1 3.15Å; K615-E618 PolarHBondContact NZ-OE1 2.89Å; K615-E618 PolarHBondContact O-N 3.37Å; K615-E618 VanDerWaalsContact O-N 3.17Å
616A95.4Very high97.2Very high24 Ų2448 Ų4820%0.19826%0.26CS..G310 helixtrans-56-41.7179.100000112.5K555 E618 R619K555-A616 HydrophobicContact CB-CB 3.88Å; K555-A616 HydrophobicContact CG-CB 4.37Å; K555-A616 WeakPolarHBondContact CG-O 3.28Å; A616-E618 VanDerWaalsContact C-N 3.25Å; A616-E618 PolarHBondContact O-N 3.45Å; A616-R619 WeakPolarHBondContact O-CB 3.32Å; A616-R619 PolarHBondContact O-N 3.38Å; A616-R619 VanDerWaalsContact O-N 3.14Å
617D94.4Very high97Very high146 Ų14648.9 Ų48.978%0.78126%0.258SS*.G310 helixtrans-70.3-19.1-177.3-55.7-30.8000113.8K615 R619K615-D617 VanDerWaalsContact C-N 3.27Å; K615-D617 PolarHBondContact O-N 3.36Å; D617-R619 VanDerWaalsContact C-N 3.3Å
618E97.1Very high96.9Very high112 Ų11251.9 Ų51.952%0.52327%0.274SS..G310 helixtrans-84-8.5176-67.7176.9-177.500112.3S613 K615 A616S613-E618 PolarHBondContact OG-OE2 3.49Å; K615-E618 HydrophobicContact CB-CB 4.25Å; K615-E618 HydrophobicContact CB-CG 3.91Å; K615-E618 HydrophobicContact CD-CG 4.43Å; K615-E618 VanDerWaalsContact CD-OE1 3.32Å; K615-E618 WeakPolarHBondContact CD-OE1 3.3Å; K615-E618 WeakPolarHBondContact CE-OE1 3.26Å; K615-E618 IonicContact NZ-OE1 3.15Å; K615-E618 PolarHBondContact NZ-OE1 2.89Å; K615-E618 PolarHBondContact O-N 3.37Å; K615-E618 VanDerWaalsContact O-N 3.17Å; A616-E618 VanDerWaalsContact C-N 3.25Å; A616-E618 PolarHBondContact O-N 3.45Å
619R98.4Very high96.6Very high4 Ų451.9 Ų51.92%0.01527%0.274CS..SBendtrans-76.9141.5175.8-57.4174.4-165.7151.211109.3E545 K555 I558 C611 S613 A616 D617E545-R619 IonicContact OE1-CZ 2.99Å; E545-R619 IonicContact OE1-NH1 2.65Å; E545-R619 PolarHBondContact OE1-NH1 2.93Å; E545-R619 IonicContact OE1-NH2 3.23Å; E545-R619 PolarHBondContact OE1-NH2 3.43Å; E545-R619 VanDerWaalsContact OE1-NH2 3.13Å; E545-R619 IonicContact OE2-CZ 3.03Å; E545-R619 IonicContact OE2-NH1 2.75Å; E545-R619 IonicContact OE2-NH2 2.86Å; E545-R619 PolarHBondContact OE2-NH2 3.46Å; K555-R619 HydrophobicContact CD-CB 4.44Å; K555-R619 PolarHBondContact NZ-O 2.98Å; K555-R619 WeakPolarHBondContact O-CD 3.5Å; K555-R619 PolarHBondContact O-NH1 3.48Å; I558-R619 HydrophobicContact CG2-CB 3.87Å; C611-R619 VanDerWaalsContact O-CD 3.3Å; C611-R619 WeakPolarHBondContact O-CD 3.33Å; S613-R619 PolarHBondContact O-NE 2.95Å; S613-R619 PolarHBondContact O-NH2 2.92Å; A616-R619 WeakPolarHBondContact O-CB 3.32Å; A616-R619 PolarHBondContact O-N 3.38Å; A616-R619 VanDerWaalsContact O-N 3.14Å; D617-R619 VanDerWaalsContact C-N 3.3Å
620P98.2Very high96.3Very high18 Ų1851.3 Ų51.312%0.11727%0.268CS..PPolyproline II helixtrans-62.1165.3178.928.7-36000111.3K555 I558 S610 E624 L625K555-P620 PolarHBondContact NZ-O 2.8Å; I558-P620 WeakPolarHBondContact CD1-O 2.85Å; I558-P620 HydrophobicContact CG2-CG 4.35Å; S610-P620 WeakPolarHBondContact O-CD 3.38Å; P620-E624 WeakPolarHBondContact CA-OE2 3.42Å; P620-E624 HydrophobicContact CB-CB 4.25Å; P620-L625 HydrophobicContact CB-CD2 4.31Å; P620-L625 HydrophobicContact CB-CG 4.14Å; P620-L625 HydrophobicContact CG-CD1 4.12Å; P620-L625 HydrophobicContact CG-CD2 3.6Å; P620-L625 HydrophobicContact CG-CG 3.74Å
621T98.1Very high96Very high42 Ų4253.5 Ų53.526%0.25828%0.276SS..PPolyproline II helixtrans-79.2162166.658.40000110.8Q623 E624 L625T621-Q623 VanDerWaalsContact C-N 3.26Å; T621-Q623 PolarHBondContact O-N 2.63Å; T621-E624 PolarHBondContact N-OE2 3.19Å; T621-E624 PolarHBondContact O-N 3.14Å; T621-E624 WeakPolarHBondContact OG1-CB 3.38Å; T621-E624 VanDerWaalsContact OG1-CD 3.27Å; T621-E624 WeakPolarHBondContact OG1-CG 3.28Å; T621-E624 PolarHBondContact OG1-N 3.34Å; T621-E624 PolarHBondContact OG1-OE2 3.46Å; T621-L625 WeakPolarHBondContact O-CG 3.49Å; T621-L625 PolarHBondContact O-N 3.14Å
622F98.1Very high95.7Very high2 Ų253.9 Ų53.91%0.00928%0.278CS..Hα-helixtrans-65.6-32.5173.4-85-69.9000112.2M487 A488 E491 L500 D557 I558 Y561 E624 L625 A626M487-F622 HydrophobicContact CB-CB 4.48Å; M487-F622 HydrophobicContact CB-CD1 3.4Å; M487-F622 HydrophobicContact CB-CD2 3.93Å; M487-F622 HydrophobicContact CB-CE1 3.36Å; M487-F622 HydrophobicContact CB-CE2 3.89Å; M487-F622 HydrophobicContact CB-CG 3.69Å; M487-F622 HydrophobicContact CB-CZ 3.62Å; M487-F622 HydrophobicContact CE-CD2 4.41Å; M487-F622 HydrophobicContact CE-CE2 3.58Å; M487-F622 HydrophobicContact CE-CZ 3.65Å; M487-F622 HydrophobicContact CG-CD1 4.36Å; M487-F622 HydrophobicContact CG-CE1 3.84Å; M487-F622 HydrophobicContact CG-CE2 4.47Å; M487-F622 HydrophobicContact CG-CZ 3.91Å; A488-F622 VanDerWaalsContact CA-CB 3.5Å; A488-F622 HydrophobicContact CB-CB 3.89Å; E491-F622 HydrophobicContact CB-CB 4.46Å; E491-F622 HydrophobicContact CB-CD2 4.28Å; E491-F622 PolarHBondContact OE1-N 2.9Å; E491-F622 PolarHBondContact OE2-N 2.74Å; L500-F622 HydrophobicContact CD2-CZ 4.2Å; D557-F622 HydrophobicContact CB-CE2 3.78Å; D557-F622 HydrophobicContact CB-CZ 4.02Å; I558-F622 HydrophobicContact CD1-CD2 4.38Å; I558-F622 HydrophobicContact CD1-CE2 4.49Å; I558-F622 HydrophobicContact CG1-CD2 3.86Å; I558-F622 HydrophobicContact CG1-CE1 4.44Å; I558-F622 HydrophobicContact CG1-CE2 3.69Å; I558-F622 HydrophobicContact CG1-CG 4.32Å; I558-F622 HydrophobicContact CG1-CZ 3.99Å; Y561-F622 HydrophobicContact CD1-CE1 4.34Å; Y561-F622 HydrophobicContact CD2-CE1 4.09Å; Y561-F622 AromaticContact CG-CE1 3.77Å; Y561-F622 HydrophobicContact CG-CE1 3.77Å; F622-E624 PolarHBondContact O-N 3.42Å; F622-L625 HydrophobicContact CD1-CD1 4.1Å; F622-L625 HydrophobicContact CE1-CD1 4.37Å; F622-L625 PolarHBondContact O-N 3.44Å; F622-A626 WeakPolarHBondContact O-CB 3.48Å; F622-A626 PolarHBondContact O-N 3.32Å
623Q96.4Very high95.3Very high108 Ų10853.9 Ų53.951%0.50528%0.279SS..Hα-helixtrans-59.3-45.3173-174.562.337.100111.9T621 L627T621-Q623 VanDerWaalsContact C-N 3.26Å; T621-Q623 PolarHBondContact O-N 2.63Å; Q623-L627 WeakPolarHBondContact O-CG 3.49Å; Q623-L627 PolarHBondContact O-N 3.37Å
624E97.4Very high94.7Very high98 Ų9859.1 Ų59.146%0.45830%0.296SS..Hα-helixtrans-66-40.1175.8-72.3163.6153.300111.7P620 T621 F622 L627 N628P620-E624 WeakPolarHBondContact CA-OE2 3.42Å; P620-E624 HydrophobicContact CB-CB 4.25Å; T621-E624 PolarHBondContact N-OE2 3.19Å; T621-E624 PolarHBondContact O-N 3.14Å; T621-E624 WeakPolarHBondContact OG1-CB 3.38Å; T621-E624 VanDerWaalsContact OG1-CD 3.27Å; T621-E624 WeakPolarHBondContact OG1-CG 3.28Å; T621-E624 PolarHBondContact OG1-N 3.34Å; T621-E624 PolarHBondContact OG1-OE2 3.46Å; F622-E624 PolarHBondContact O-N 3.42Å; E624-L627 PolarHBondContact O-N 3.36Å; E624-N628 WeakPolarHBondContact O-CB 3.38Å; E624-N628 PolarHBondContact O-N 3.41Å; E624-N628 PolarHBondContact O-ND2 2.79Å; E624-N628 VanDerWaalsContact O-ND2 3.13Å
625L98.1Very high94.4Very high0 Ų060.2 Ų60.20%030%0.298CS..Hα-helixtrans-62.8-44.9176.5-73.3171.5000112.2I558 Y561 I607 P620 T621 F622 L627 N628 V629I558-L625 HydrophobicContact CG1-CD1 4.26Å; I558-L625 HydrophobicContact CG2-CD1 4.06Å; Y561-L625 HydrophobicContact CD1-CD1 3.72Å; Y561-L625 HydrophobicContact CE1-CB 4.42Å; Y561-L625 HydrophobicContact CE1-CD1 3.99Å; Y561-L625 HydrophobicContact CE1-CD2 4.37Å; I607-L625 HydrophobicContact CG2-CD2 3.66Å; P620-L625 HydrophobicContact CB-CD2 4.31Å; P620-L625 HydrophobicContact CB-CG 4.14Å; P620-L625 HydrophobicContact CG-CD1 4.12Å; P620-L625 HydrophobicContact CG-CD2 3.6Å; P620-L625 HydrophobicContact CG-CG 3.74Å; T621-L625 WeakPolarHBondContact O-CG 3.49Å; T621-L625 PolarHBondContact O-N 3.14Å; F622-L625 HydrophobicContact CD1-CD1 4.1Å; F622-L625 HydrophobicContact CE1-CD1 4.37Å; F622-L625 PolarHBondContact O-N 3.44Å; L625-L627 VanDerWaalsContact C-N 3.33Å; L625-L627 PolarHBondContact O-N 3.34Å; L625-N628 PolarHBondContact O-N 3Å; L625-V629 WeakPolarHBondContact O-CB 3.34Å; L625-V629 VanDerWaalsContact O-CG2 3.26Å; L625-V629 WeakPolarHBondContact O-CG2 3.22Å; L625-V629 PolarHBondContact O-N 3.32Å
626A95.3Very high93.6Very high10 Ų1057 Ų578%0.08329%0.286CS..Hα-helixtrans-60.4-43.6178.200000111.4S484 E485 F622 Q630S484-A626 WeakPolarHBondContact OG-CA 3.39Å; E485-A626 HydrophobicContact CG-CB 4.36Å; F622-A626 WeakPolarHBondContact O-CB 3.48Å; F622-A626 PolarHBondContact O-N 3.32Å; A626-Q630 WeakPolarHBondContact O-CB 3.18Å; A626-Q630 PolarHBondContact O-N 3.48Å
627L93.9Very high92.6Very high90 Ų9062 Ų6247%0.47131%0.306SS..Hα-helixtrans-63.7-49174.6-69172.4000111.9Q623 E624 L625 V629 Q630 D631Q623-L627 WeakPolarHBondContact O-CG 3.49Å; Q623-L627 PolarHBondContact O-N 3.37Å; E624-L627 PolarHBondContact O-N 3.36Å; L625-L627 VanDerWaalsContact C-N 3.33Å; L625-L627 PolarHBondContact O-N 3.34Å; L627-V629 VanDerWaalsContact C-N 3.31Å; L627-V629 PolarHBondContact O-N 3.16Å; L627-Q630 PolarHBondContact O-N 3.01Å; L627-D631 WeakPolarHBondContact O-CB 3.49Å; L627-D631 PolarHBondContact O-N 3.18Å
628N95.1Very high92.5Very high79 Ų7957.9 Ų57.942%0.42228%0.282SS..Hα-helixtrans-60.4-40.3-179.7-72.6-26.7000112.5E624 L625 L632E624-N628 WeakPolarHBondContact O-CB 3.38Å; E624-N628 PolarHBondContact O-N 3.41Å; E624-N628 PolarHBondContact O-ND2 2.79Å; E624-N628 VanDerWaalsContact O-ND2 3.13Å; L625-N628 PolarHBondContact O-N 3Å; N628-L632 VanDerWaalsContact O-CB 3.32Å; N628-L632 WeakPolarHBondContact O-CB 3.12Å; N628-L632 PolarHBondContact O-N 2.77Å
629V93.7Very high92.3Very high0 Ų055 Ų550%027%0.269CS..Hα-helixtrans-69.3-42.1177171.20000110.8L477 K481 I607 L625 L627 L632 L633L477-V629 HydrophobicContact CD1-CG1 3.78Å; L477-V629 HydrophobicContact CG-CG1 3.96Å; K481-V629 HydrophobicContact CB-CG1 3.62Å; K481-V629 HydrophobicContact CG-CG1 4.16Å; I607-V629 HydrophobicContact CD1-CG2 4.09Å; L625-V629 WeakPolarHBondContact O-CB 3.34Å; L625-V629 VanDerWaalsContact O-CG2 3.26Å; L625-V629 WeakPolarHBondContact O-CG2 3.22Å; L625-V629 PolarHBondContact O-N 3.32Å; L627-V629 VanDerWaalsContact C-N 3.31Å; L627-V629 PolarHBondContact O-N 3.16Å; V629-L632 PolarHBondContact O-N 3.49Å; V629-L633 HydrophobicContact CG1-CD1 4.33Å; V629-L633 WeakPolarHBondContact O-CG 3.37Å; V629-L633 PolarHBondContact O-N 2.69Å
630Q91.5Very high91.9Very high42 Ų4257.8 Ų57.820%0.19628%0.283CS..Hα-helixtrans-63.2-43.7177176.26387.900112.2A626 L627 L633 Y634A626-Q630 WeakPolarHBondContact O-CB 3.18Å; A626-Q630 PolarHBondContact O-N 3.48Å; L627-Q630 PolarHBondContact O-N 3.01Å; Q630-L633 WeakPolarHBondContact O-CB 3.44Å; Q630-L633 PolarHBondContact O-N 2.89Å; Q630-Y634 HydrophobicContact CG-CD2 4.11Å; Q630-Y634 HydrophobicContact CG-CE2 3.58Å; Q630-Y634 WeakPolarHBondContact O-CD2 3.44Å; Q630-Y634 PolarHBondContact O-N 3.24Å; Q630-Y634 VanDerWaalsContact O-N 3.11Å
631D91.9Very high91.6Very high91 Ų9160.2 Ų60.249%0.48729%0.293SS..Hα-helixtrans-63.7-44.1176.2-73.3-16.5000110.8L627 L633 Y634 E635L627-D631 WeakPolarHBondContact O-CB 3.49Å; L627-D631 PolarHBondContact O-N 3.18Å; D631-L633 VanDerWaalsContact C-N 3.3Å; D631-L633 PolarHBondContact O-N 2.83Å; D631-Y634 WeakPolarHBondContact O-CB 3.4Å; D631-Y634 PolarHBondContact O-N 2.92Å; D631-Y634 VanDerWaalsContact O-N 3.15Å; D631-E635 PolarHBondContact O-N 3.18Å; D631-E635 VanDerWaalsContact O-N 3.1Å
632L91.9Very high91.2Very high9 Ų961.3 Ų61.35%0.04730%0.295CS..Hα-helixtrans-64.5-33.9176.3-175.859.3000112.5L477 K603 V604 I607 N628 V629 E635 L636L477-L632 HydrophobicContact CD2-CB 4.15Å; L477-L632 HydrophobicContact CD2-CD2 3.99Å; L477-L632 HydrophobicContact CD2-CG 3.8Å; K603-L632 HydrophobicContact CB-CD1 3.79Å; K603-L632 HydrophobicContact CB-CD2 4.01Å; K603-L632 HydrophobicContact CD-CD1 3.57Å; K603-L632 HydrophobicContact CG-CD1 4.34Å; V604-L632 HydrophobicContact CG2-CD2 3.71Å; I607-L632 HydrophobicContact CD1-CD2 3.89Å; N628-L632 VanDerWaalsContact O-CB 3.32Å; N628-L632 WeakPolarHBondContact O-CB 3.12Å; N628-L632 PolarHBondContact O-N 2.77Å; V629-L632 PolarHBondContact O-N 3.49Å; L632-E635 PolarHBondContact O-N 3.2Å; L632-L636 HydrophobicContact CD1-CD1 4.14Å; L632-L636 HydrophobicContact CD1-CG 4.25Å; L632-L636 HydrophobicContact CG-CD1 3.99Å; L632-L636 HydrophobicContact CG-CG 4.5Å; L632-L636 VanDerWaalsContact O-CG 3.28Å; L632-L636 WeakPolarHBondContact O-CG 3.28Å; L632-L636 PolarHBondContact O-N 2.97Å
633L89.1Confident90.7Very high4 Ų465.3 Ų65.32%0.02131%0.314CS..Hα-helixtrans-61.2-45.1171.9-85.1167.4000111.4V474 L477 E478 K481 V629 Q630 D631 E635 L636 Q637V474-L633 HydrophobicContact CG1-CD2 3.95Å; L477-L633 HydrophobicContact CB-CD2 3.75Å; L477-L633 HydrophobicContact CB-CG 4.25Å; L477-L633 HydrophobicContact CD2-CB 4.49Å; L477-L633 HydrophobicContact CD2-CD2 3.83Å; L477-L633 HydrophobicContact CD2-CG 3.7Å; L477-L633 HydrophobicContact CG-CD1 4.46Å; L477-L633 HydrophobicContact CG-CD2 3.83Å; L477-L633 HydrophobicContact CG-CG 3.77Å; E478-L633 HydrophobicContact CG-CD1 4.33Å; E478-L633 HydrophobicContact CG-CD2 3.79Å; K481-L633 HydrophobicContact CB-CD1 3.74Å; K481-L633 HydrophobicContact CD-CD1 3.77Å; K481-L633 HydrophobicContact CG-CD1 3.85Å; V629-L633 HydrophobicContact CG1-CD1 4.33Å; V629-L633 WeakPolarHBondContact O-CG 3.37Å; V629-L633 PolarHBondContact O-N 2.69Å; Q630-L633 WeakPolarHBondContact O-CB 3.44Å; Q630-L633 PolarHBondContact O-N 2.89Å; D631-L633 VanDerWaalsContact C-N 3.3Å; D631-L633 PolarHBondContact O-N 2.83Å; L633-E635 VanDerWaalsContact C-N 3.26Å; L633-E635 PolarHBondContact O-N 3.13Å; L633-L636 PolarHBondContact O-N 3Å; L633-Q637 WeakPolarHBondContact O-CG 3.44Å; L633-Q637 PolarHBondContact O-N 3.35Å; L633-Q637 VanDerWaalsContact O-N 3.15Å
634Y86.4Confident90.3Very high137 Ų13762.2 Ų62.254%0.53730%0.301SS..Hα-helixtrans-63.2-31.3177-73.4-58.5000113.2Q630 D631Q630-Y634 HydrophobicContact CG-CD2 4.11Å; Q630-Y634 HydrophobicContact CG-CE2 3.58Å; Q630-Y634 WeakPolarHBondContact O-CD2 3.44Å; Q630-Y634 PolarHBondContact O-N 3.24Å; Q630-Y634 VanDerWaalsContact O-N 3.11Å; D631-Y634 WeakPolarHBondContact O-CB 3.4Å; D631-Y634 PolarHBondContact O-N 2.92Å; D631-Y634 VanDerWaalsContact O-N 3.15Å
635E87Confident89.8Confident118 Ų11859.5 Ų59.555%0.55129%0.289SS*.Hα-helixtrans-74.8-25.9176.5-68.7-177.2163.700113.7K603 D631 L632 L633K603-E635 IonicContact NZ-OE1 2.65Å; K603-E635 PolarHBondContact NZ-OE1 3.38Å; K603-E635 IonicContact NZ-OE2 3.19Å; K603-E635 PolarHBondContact NZ-OE2 3.34Å; D631-E635 PolarHBondContact O-N 3.18Å; D631-E635 VanDerWaalsContact O-N 3.1Å; L632-E635 PolarHBondContact O-N 3.2Å; L633-E635 VanDerWaalsContact C-N 3.26Å; L633-E635 PolarHBondContact O-N 3.13Å
636L77.8Confident89.1Confident63 Ų6364.4 Ų64.433%0.3331%0.313SS..Hα-helixtrans-96.7-12.3-174.8-67.8175.1000113.7V474 L477 L632 L633V474-L636 HydrophobicContact CG2-CB 4.15Å; L477-L636 HydrophobicContact CD2-CD1 3.88Å; L632-L636 HydrophobicContact CD1-CD1 4.14Å; L632-L636 HydrophobicContact CD1-CG 4.25Å; L632-L636 HydrophobicContact CG-CD1 3.99Å; L632-L636 HydrophobicContact CG-CG 4.5Å; L632-L636 VanDerWaalsContact O-CG 3.28Å; L632-L636 WeakPolarHBondContact O-CG 3.28Å; L632-L636 PolarHBondContact O-N 2.97Å; L633-L636 PolarHBondContact O-N 3Å
637Q75.2Confident88.5Confident130 Ų13069.4 Ų69.461%0.60733%0.334SS*.  trans-88.90172.7-72.5178.4-7.200110.8V474 L633V474-Q637 HydrophobicContact CG1-CG 4.04Å; L633-Q637 WeakPolarHBondContact O-CG 3.44Å; L633-Q637 PolarHBondContact O-N 3.35Å; L633-Q637 VanDerWaalsContact O-N 3.15Å

Retrieved 637 of 637 residues in 628.1 ms (Link to these results)