A0A087X4G7_POEFO Loading...

Sorting nexin-2

Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity. Required for retrograde endosome-to-TGN transport of TGN38. Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN.

AlphaFold DB , UniProt , Accession A0A087X4G7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 514 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.5	Very low	42.5	Very low	241 Å²	241	139 Å²	139	100%	1.187	79%	0.794	S	S	*	*				0	84	0	-75.6	172.1	158	0	0	105.4
2	A	35.8	Very low	41.6	Very low	98 Å²	98	147.8 Å²	147.8	81%	0.81	81%	0.805	S	S	*	*				65.2	93	99.6	0	0	0	0	0	109.3
3	D	36.3	Very low	41	Very low	144 Å²	144	144.2 Å²	144.2	77%	0.77	79%	0.791	S	S	*	*			cis	80.2	126.2	41.2	-143.2	13.1	0	0	0	114.4
4	T	37.8	Very low	40.4	Very low	117 Å²	117	145.3 Å²	145.3	72%	0.718	80%	0.795	S	S	*	*			trans	66.5	121.5	155.5	41.6	0	0	0	0	119.5
5	A	38.2	Very low	39.8	Very low	83 Å²	83	147.3 Å²	147.3	69%	0.686	79%	0.794	S	S	*	*				115.6	159.2	80.3	0	0	0	0	0	108.1
6	R	37	Very low	39.2	Very low	222 Å²	222	149.6 Å²	149.6	84%	0.838	80%	0.797	S	S	*	*			cis	-174.5	135.7	12.7	-124.1	165.3	174.2	167.3	-2.2	105.6
7	D	34.7	Very low	38.9	Very low	146 Å²	146	150.2 Å²	150.2	78%	0.781	79%	0.794	S	S	*	*				56.2	165.2	116.4	-93.9	-12	0	0	0	124.2
8	P	55.7	Low	38.7	Very low	108 Å²	108	148.7 Å²	148.7	70%	0.701	79%	0.792	S	S	*	*				-124.4	-118.7	-125.5	25.7	2.3	0	0	0	115.5
9	P	63.7	Low	38.4	Very low	107 Å²	107	149.6 Å²	149.6	70%	0.695	79%	0.791	S	S	*	*				-104.9	-157.6	-119.7	35.4	-14.8	0	0	0	113.6
10	P	51.5	Low	38.2	Very low	127 Å²	127	150 Å²	150	83%	0.825	79%	0.793	S	S	*	*				-147.9	159.4	99.5	37.9	-20.6	0	0	0	117
11	D	37.4	Very low	37.9	Very low	136 Å²	136	145.7 Å²	145.7	73%	0.727	79%	0.785	S	S	*	*			trans	-75.4	155.8	163.6	-157.9	-1.6	0	0	0	111
12	R	31.5	Very low	37.7	Very low	244 Å²	244	144 Å²	144	92%	0.921	77%	0.774	S	S	*	*			trans	-146.5	101.6	159.1	-100.4	-168	177.4	-172.7	-2.1	109.9
13	T	34	Very low	37.6	Very low	101 Å²	101	145.9 Å²	145.9	62%	0.62	77%	0.77	S	S	*	*			trans	-59.1	142.5	148	49.4	0	0	0	0	111
14	D	32	Very low	37.3	Very low	160 Å²	160	145.3 Å²	145.3	86%	0.856	77%	0.767	S	S	*	*				-165.7	141.6	124	-104.1	-19.5	0	0	0	113
15	F	31.3	Very low	37.4	Very low	176 Å²	176	148.7 Å²	148.7	77%	0.772	77%	0.772	S	S	*	*			trans	-71.3	153.7	178.2	-82.7	-112.8	0	0	0	112.4
16	H	31	Very low	37.5	Very low	184 Å²	184	150.5 Å²	150.5	85%	0.852	78%	0.777	S	S	*	*			trans	-147.2	111.7	135.2	-126.4	-56	0	0	0	110.3
17	E	34.4	Very low	37.5	Very low	160 Å²	160	147.7 Å²	147.7	75%	0.748	77%	0.773	S	S	*	*			trans	-69.5	145.2	155.6	-73.7	170.7	138.3	0	0	109.9
18	V	35.4	Very low	37.9	Very low	123 Å²	123	146.2 Å²	146.2	75%	0.745	77%	0.772	S	S	*	*			trans	-147.9	113.6	134.5	-174	0	0	0	0	108
19	E	33	Very low	36.7	Very low	166 Å²	166	145.9 Å²	145.9	78%	0.776	77%	0.772	S	S	*	*			trans	13.9	146	134.7	-65.2	170.4	158	0	0	117.8
20	D	34.2	Very low	35.1	Very low	156 Å²	156	145.7 Å²	145.7	83%	0.834	78%	0.779	S	S	*	*			cis	-162.7	163.8	23.8	-95	-35.9	0	0	0	104.4
21	G	32	Very low	34	Very low	60 Å²	60	144.5 Å²	144.5	62%	0.619	78%	0.78	S	S	*	*			cis	158.1	144.6	18.2	0	0	0	0	0	106.7
22	E	35.1	Very low	33.6	Very low	205 Å²	205	144.5 Å²	144.5	96%	0.958	79%	0.785	S	S	*	*			trans	76.8	150.7	152.7	-54.9	-166.9	151.5	0	0	122
23	D	32.4	Very low	33.9	Very low	138 Å²	138	138.3 Å²	138.3	74%	0.738	78%	0.777	S	S	*	*			trans	-127	170.9	-149.4	-158.2	-3	0	0	0	107.1
24	L	31.3	Very low	33.6	Very low	132 Å²	132	141.9 Å²	141.9	69%	0.691	79%	0.786	S	S	*	*			trans	77.6	113.9	156.2	-60.9	146.3	0	0	0	120.5
25	F	39.3	Very low	33.4	Very low	188 Å²	188	140 Å²	140	83%	0.825	79%	0.786	S	S	*	*				30.8	142.8	129.4	-76.4	-80.8	0	0	0	120.2
26	P	41.1	Very low	33.1	Very low	122 Å²	122	140.1 Å²	140.1	79%	0.792	79%	0.789	S	S	*	*				-156.9	165.5	74.1	39.1	-17	0	0	0	119.2
27	E	36	Very low	34.2	Very low	162 Å²	162	136.5 Å²	136.5	76%	0.757	78%	0.782	S	S	*	*			trans	-48.2	164.2	152.4	-104.8	-168.6	-166.1	0	0	113.4
28	P	43.7	Very low	33.7	Very low	116 Å²	116	133 Å²	133	75%	0.753	78%	0.78	S	S	*	*				-158.4	155.9	69.4	38.9	-15.1	0	0	0	120.8
29	S	29.5	Very low	33.3	Very low	101 Å²	101	131.5 Å²	131.5	71%	0.706	78%	0.775	S	S	*	*			trans	41.9	128.7	131.5	-44.3	0	0	0	0	125.8
30	A	30.8	Very low	33	Very low	103 Å²	103	131.3 Å²	131.3	85%	0.851	78%	0.778	S	S	*	*				81.9	118.2	128	0	0	0	0	0	122.6
31	A	28.1	Very low	32.6	Very low	102 Å²	102	128.6 Å²	128.6	84%	0.843	77%	0.771	S	S	*	*				178.6	130.7	114.9	0	0	0	0	0	112.6
32	T	28.8	Very low	32.5	Very low	135 Å²	135	130 Å²	130	83%	0.828	78%	0.778	S	S	*	*			trans	-70.7	170.7	161.3	7.8	0	0	0	0	110.9
33	P	38.9	Very low	32.3	Very low	115 Å²	115	126 Å²	126	75%	0.747	77%	0.767	S	S	*	*			cis	-145.5	175.6	37.1	36.4	-12.1	0	0	0	118.5
34	E	27.1	Very low	32.2	Very low	175 Å²	175	126.1 Å²	126.1	82%	0.818	77%	0.767	S	S	*	*			trans	-10	140.1	159.1	-61.4	172.5	149.3	0	0	119.9
35	S	27.7	Very low	32.1	Very low	121 Å²	121	128.1 Å²	128.1	85%	0.846	78%	0.777	S	S	*	*				161	131.9	105	44.3	0	0	0	0	112.5
36	Q	25.3	Very low	31.7	Very low	179 Å²	179	123.7 Å²	123.7	84%	0.836	77%	0.769	S	S	*	*			trans	-59.9	-176.4	163.5	-94.4	-173.1	-8.7	0	0	112.3
37	P	53.3	Low	31.1	Very low	108 Å²	108	123.2 Å²	123.2	70%	0.701	76%	0.764	S	S	*	*			cis	-138.1	-149.7	-38.7	37.9	-18.4	0	0	0	109.4
38	A	24.5	Very low	30.8	Very low	86 Å²	86	122.7 Å²	122.7	71%	0.711	77%	0.767	S	S	*	*			trans	98.3	142.5	154.1	0	0	0	0	0	115.1
39	S	27.8	Very low	30.1	Very low	91 Å²	91	120.8 Å²	120.8	64%	0.636	76%	0.761	S	S	*	*			cis	166.1	149.9	-7.8	51.7	0	0	0	0	105.6
40	L	26.9	Very low	30.2	Very low	162 Å²	162	123.8 Å²	123.8	85%	0.848	77%	0.769	S	S	*	*			trans	68.6	155.1	150.6	-62	163.1	0	0	0	115.8
41	S	26	Very low	30	Very low	99 Å²	99	122.2 Å²	122.2	69%	0.692	76%	0.762	S	S	*	*			cis	-176.6	132.7	-1	41.6	0	0	0	0	104.4
42	A	28.7	Very low	30.6	Very low	91 Å²	91	123.9 Å²	123.9	75%	0.752	77%	0.765	S	S	*	*				85.2	149.4	106.5	0	0	0	0	0	117.7
43	V	31.9	Very low	30.9	Very low	120 Å²	120	126.9 Å²	126.9	73%	0.727	77%	0.766	S	S	*	*			trans	104.7	98.8	149.2	-164.1	0	0	0	0	118.4
44	D	29.4	Very low	30.5	Very low	141 Å²	141	129.4 Å²	129.4	75%	0.754	77%	0.768	S	S	*	*				49.4	140.1	126.7	-55.4	-29.3	0	0	0	123.3
45	I	30.6	Very low	30.6	Very low	174 Å²	174	127.4 Å²	127.4	89%	0.892	76%	0.763	S	S	*	*				-160.3	136.3	118.2	-95.3	151.8	0	0	0	112.5
46	S	29	Very low	30.7	Very low	94 Å²	94	125.4 Å²	125.4	66%	0.657	75%	0.749	S	S	*	*			trans	-62.7	158.7	-177.2	-173	0	0	0	0	118.4
47	T	30	Very low	30.9	Very low	112 Å²	112	126 Å²	126	69%	0.687	75%	0.749	S	S	*	*				161.9	132	103.8	38.9	0	0	0	0	117.1
48	N	28.7	Very low	29.8	Very low	152 Å²	152	129.3 Å²	129.3	81%	0.813	75%	0.753	S	S	*	*			trans	71.8	147.7	140.9	-70.1	-9	0	0	0	123.1
49	A	30.4	Very low	30	Very low	76 Å²	76	132.6 Å²	132.6	63%	0.628	76%	0.759	S	S	*	*			cis	-177	157	-21.2	0	0	0	0	0	108.7
50	N	30.5	Very low	30.2	Very low	163 Å²	163	134.2 Å²	134.2	87%	0.872	76%	0.76	S	S	*	*			trans	91.4	106.9	158.5	-66.4	-8.5	0	0	0	121.2
51	G	26	Very low	30.5	Very low	70 Å²	70	134.1 Å²	134.1	72%	0.722	76%	0.76	S	S	*	*			trans	-104.2	-164.8	152.8	0	0	0	0	0	112.4
52	P	42.2	Very low	30.9	Very low	137 Å²	137	136.7 Å²	136.7	89%	0.89	77%	0.766	S	S	*	*				-134	155.2	125.8	32.6	-18.3	0	0	0	114.8
53	K	33.5	Very low	31.1	Very low	199 Å²	199	140.6 Å²	140.6	87%	0.865	77%	0.769	S	S	*	*			trans	-74.1	160	-171.9	-61.8	171	175.7	179.3	0	113.1
54	Q	32.2	Very low	31.3	Very low	167 Å²	167	142.2 Å²	142.2	78%	0.78	77%	0.774	S	S	*	*				-178.9	155.6	74.4	-92.4	-171.7	-75.1	0	0	107.7
55	D	28.6	Very low	31.9	Very low	133 Å²	133	142 Å²	142	71%	0.711	77%	0.772	S	S	*	*			cis	-149.5	158.9	15.1	-94.6	-31.7	0	0	0	110.3
56	S	28.8	Very low	32.2	Very low	79 Å²	79	143.4 Å²	143.4	55%	0.552	77%	0.772	S	S	*	*			trans	-65.4	150.7	-175.9	48.1	0	0	0	0	116.6
57	F	30.1	Very low	32.4	Very low	191 Å²	191	143.4 Å²	143.4	84%	0.838	78%	0.778	S	S	*	*				-170.6	140.3	105.9	-97.2	-76.6	0	0	0	110.4
58	F	29.7	Very low	32.5	Very low	179 Å²	179	147.4 Å²	147.4	79%	0.785	79%	0.789	S	S	*	*			trans	-54.1	154.3	176.6	-59.5	-97.7	0	0	0	111.5
59	D	29.1	Very low	32.6	Very low	155 Å²	155	145.1 Å²	145.1	83%	0.829	79%	0.791	S	S	*	*				-163.5	162.5	51.7	-132.2	-16.4	0	0	0	111.8
60	D	32	Very low	32.8	Very low	125 Å²	125	147.8 Å²	147.8	67%	0.668	80%	0.799	S	S	*	*			trans	-64.4	142.4	174.4	-169.1	22.8	0	0	0	111.7
61	D	32.6	Very low	32.9	Very low	159 Å²	159	149.4 Å²	149.4	85%	0.85	80%	0.802	S	S	*	*			trans	-164.1	116.4	149.9	-94.4	-29.5	0	0	0	111.8	E63	D61-E63 PolarHBondContact O-N 2.91Å
62	N	34.3	Very low	33.3	Very low	153 Å²	153	155 Å²	155	82%	0.818	81%	0.809	S	S	*	*			trans	-68	112.4	162.6	-89.1	-57.6	0	0	0	108.9	D64	N62-D64 PolarHBondContact O-N 3.32Å
63	E	33.9	Very low	32.7	Very low	173 Å²	173	155.4 Å²	155.4	81%	0.808	81%	0.809	S	S	*	*			trans	-80.3	103	165.9	-76.7	-168.4	159.4	0	0	110.7	D61 L65	D61-E63 PolarHBondContact O-N 2.91Å; E63-L65 PolarHBondContact O-N 3Å
64	D	35	Very low	32.5	Very low	154 Å²	154	151.6 Å²	151.6	82%	0.824	81%	0.807	S	S	*	*			trans	-70.8	95.4	163.5	-153.4	1.3	0	0	0	108.8	N62 F66	N62-D64 PolarHBondContact O-N 3.32Å; D64-F66 PolarHBondContact O-N 3.03Å
65	L	42.3	Very low	32.7	Very low	138 Å²	138	152 Å²	152	72%	0.723	81%	0.814	S	S	*	*			trans	-82.4	41.6	-170.7	-157.4	90.8	0	0	0	113.4	E63	E63-L65 PolarHBondContact O-N 3Å
66	F	38.4	Very low	32.7	Very low	202 Å²	202	153.5 Å²	153.5	89%	0.886	82%	0.822	S	S	*	*			trans	-155.1	74.6	171.3	-85.1	-76.9	0	0	0	112	D64	D64-F66 PolarHBondContact O-N 3.03Å
67	A	32.6	Very low	33.1	Very low	95 Å²	95	154.8 Å²	154.8	79%	0.785	83%	0.831	S	S	*	*			trans	-152.3	142.5	157.9	0	0	0	0	0	111.2
68	E	31.3	Very low	33.2	Very low	196 Å²	196	151.6 Å²	151.6	92%	0.916	83%	0.829	S	S	*	*			trans	86.8	99.3	174.7	-70	-169.9	136.3	0	0	119.4
69	A	31.5	Very low	33.5	Very low	103 Å²	103	152.3 Å²	152.3	85%	0.851	84%	0.835	S	S	*	*			trans	-156	73	134.9	0	0	0	0	0	109
70	T	33.8	Very low	33.8	Very low	133 Å²	133	156.7 Å²	156.7	82%	0.816	84%	0.84	S	S	*	*			trans	-124.9	88.8	159	47	0	0	0	0	106.7
71	E	32.7	Very low	33.7	Very low	197 Å²	197	158.4 Å²	158.4	92%	0.921	85%	0.849	S	S	*	*			trans	-98.1	117.1	165.9	-86.9	-169.4	150.1	0	0	109.1
72	E	35	Very low	33.8	Very low	187 Å²	187	156.8 Å²	156.8	87%	0.874	85%	0.845	S	S	*	*			trans	-74.5	127.2	172.6	-58.9	-151.2	162.2	0	0	110.5	S74	E72-S74 PolarHBondContact O-N 3.21Å
73	V	29.4	Very low	33.7	Very low	146 Å²	146	157.8 Å²	157.8	89%	0.885	85%	0.849	S	S	*	*			trans	-83.4	106.4	172.4	-89.3	0	0	0	0	110
74	S	29.1	Very low	33.7	Very low	119 Å²	119	157.3 Å²	157.3	83%	0.832	85%	0.851	S	S	*	*			trans	-71.2	137.9	168.9	-80.4	0	0	0	0	112.1	E72	E72-S74 PolarHBondContact O-N 3.21Å
75	L	36.6	Very low	33.6	Very low	176 Å²	176	155.7 Å²	155.7	92%	0.921	85%	0.852	S	S	*	*			trans	-82.7	115.3	171.6	-67.5	165.7	0	0	0	109.8
76	D	28.7	Very low	33.5	Very low	163 Å²	163	157.1 Å²	157.1	87%	0.872	86%	0.86	S	S	*	*			trans	-153.6	134.1	150.3	-156.4	12.4	0	0	0	111.1
77	S	36.1	Very low	33.8	Very low	106 Å²	106	150.6 Å²	150.6	74%	0.741	85%	0.85	S	S	*	*			trans	-107.7	143.4	-177	-68.4	0	0	0	0	110.2
78	P	34.1	Very low	34.2	Very low	125 Å²	125	152.3 Å²	152.3	81%	0.812	85%	0.853	S	S	*	*			trans	-96.7	132.1	161.2	32.8	-24.8	0	0	0	111.3
79	E	35.6	Very low	34.4	Very low	194 Å²	194	148.6 Å²	148.6	91%	0.907	85%	0.849	S	S	*	*			trans	-54.4	139.6	171	-64.4	172.8	141.8	0	0	112.2
80	R	35.1	Very low	34.6	Very low	247 Å²	247	149.6 Å²	149.6	93%	0.932	85%	0.847	S	S	*	*			trans	-140.4	138.5	158.4	-90.8	-168.2	176.3	161.2	1.3	111.9
81	D	30.7	Very low	34.6	Very low	161 Å²	161	147.8 Å²	147.8	86%	0.861	85%	0.845	S	S	*	*			trans	-55.6	147.9	-165.2	-67.6	-62.1	0	0	0	117.2
82	V	33.1	Very low	34.8	Very low	124 Å²	124	146.6 Å²	146.6	75%	0.752	84%	0.843	S	S	*	*			trans	-77.2	117.6	175.1	-178.4	0	0	0	0	110.2	L84	V82-L84 HydrophobicContact CG1-CD2 4.3Å; V82-L84 HydrophobicContact CG1-CG 4.05Å
83	L	32.4	Very low	34.7	Very low	174 Å²	174	142.9 Å²	142.9	91%	0.911	83%	0.833	S	S	*	*			trans	-112.5	106.8	159.7	-74.5	176.5	0	0	0	109.2
84	L	35.1	Very low	34.9	Very low	163 Å²	163	141.9 Å²	141.9	85%	0.853	83%	0.83	S	S	*	*			trans	-71.8	132.6	172.2	-67.3	165.7	0	0	0	110.1	V82	V82-L84 HydrophobicContact CG1-CD2 4.3Å; V82-L84 HydrophobicContact CG1-CG 4.05Å
85	S	32.6	Very low	35.1	Very low	120 Å²	120	144 Å²	144	84%	0.839	83%	0.83	S	S	*	*			trans	-140.9	120.5	160.8	177.3	0	0	0	0	109.2
86	D	39.5	Very low	35.1	Very low	169 Å²	169	141.5 Å²	141.5	90%	0.904	82%	0.822	S	S	*	*			trans	-66.3	133.1	179.7	-76.9	-42.7	0	0	0	112.9
87	G	44.8	Very low	35.3	Very low	64 Å²	64	139.1 Å²	139.1	66%	0.66	82%	0.816	S	S	*	*			trans	177	140.5	167.3	0	0	0	0	0	112.9
88	P	40.3	Very low	35.3	Very low	132 Å²	132	140 Å²	140	86%	0.857	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-78.2	138.6	-169.3	31.6	-32.7	0	0	0	112.4
89	S	36	Very low	35.4	Very low	118 Å²	118	140.3 Å²	140.3	83%	0.825	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-67.7	136.6	176.2	-52.6	0	0	0	0	112.2
90	P	35.8	Very low	35.3	Very low	124 Å²	124	136.6 Å²	136.6	81%	0.805	81%	0.814	S	S	*	*	P	Polyproline II helix	trans	-81.7	136.7	171	30.9	-29.2	0	0	0	111.3
91	A	34.6	Very low	35.4	Very low	94 Å²	94	130.9 Å²	130.9	78%	0.777	81%	0.807	S	S	*	*	P	Polyproline II helix	trans	-68.6	137.6	176.7	0	0	0	0	0	112.2
92	I	36	Very low	35.6	Very low	172 Å²	172	131 Å²	131	88%	0.882	81%	0.805	S	S	*	*	P	Polyproline II helix	trans	-75.9	120.8	171.4	-61.9	172.9	0	0	0	108.2
93	T	34.1	Very low	35.8	Very low	110 Å²	110	130.8 Å²	130.8	68%	0.675	81%	0.805	S	S	*	*			trans	-110.2	143.8	169.4	44.2	0	0	0	0	110
94	P	32.4	Very low	35.8	Very low	124 Å²	124	128.2 Å²	128.2	81%	0.805	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-77.4	134.1	-179.6	29.6	-31.5	0	0	0	111.3
95	I	34.3	Very low	35.6	Very low	164 Å²	164	132.4 Å²	132.4	84%	0.841	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-92.6	116.9	-178.4	-52.1	174.6	0	0	0	109.5
96	T	35.3	Very low	35.7	Very low	123 Å²	123	133.8 Å²	133.8	76%	0.755	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-87.1	141.7	167.6	-35.6	0	0	0	0	108.7
97	P	34.4	Very low	35.2	Very low	113 Å²	113	129.3 Å²	129.3	73%	0.734	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-80.2	140	-175.3	30.9	-33.4	0	0	0	112.1
98	P	34.9	Very low	34.8	Very low	125 Å²	125	134.4 Å²	134.4	81%	0.812	80%	0.799	S	S	*	*	P	Polyproline II helix	trans	-92.7	127.2	170.2	33.2	-27	0	0	0	111.5
99	T	37.3	Very low	34.4	Very low	132 Å²	132	134.3 Å²	134.3	81%	0.81	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-69.8	121.7	161.4	-51.7	0	0	0	0	109.3
100	S	33	Very low	34.3	Very low	115 Å²	115	136.8 Å²	136.8	80%	0.804	80%	0.795	S	S	*	*			trans	-162.6	131.2	153.3	-81.3	0	0	0	0	111.9
101	V	37.6	Very low	34	Very low	128 Å²	128	136.8 Å²	136.8	78%	0.776	79%	0.788	S	S	*	*			trans	-77.9	132.6	-173.9	-175.3	0	0	0	0	109.8
102	I	34.5	Very low	33.8	Very low	162 Å²	162	139 Å²	139	83%	0.831	79%	0.787	S	S	*	*			trans	-132.4	113.3	164.5	-60.3	-179.6	0	0	0	109.7
103	T	36.5	Very low	34	Very low	121 Å²	121	138 Å²	138	74%	0.742	78%	0.78	S	S	*	*	P	Polyproline II helix	trans	-72.1	139.4	170.2	-29	0	0	0	0	110.7
104	P	32.9	Very low	34.3	Very low	119 Å²	119	141.8 Å²	141.8	77%	0.773	79%	0.788	S	S	*	*	P	Polyproline II helix	trans	-90.5	133.6	169.9	12.7	4.1	0	0	0	111.9
105	R	30.7	Very low	34.6	Very low	251 Å²	251	142.7 Å²	142.7	95%	0.947	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-85.4	133.4	170.4	-101.1	179.6	169	153.8	-3.2	110.4
106	I	35.6	Very low	34.6	Very low	149 Å²	149	144.1 Å²	144.1	76%	0.764	79%	0.794	S	S	*	*	P	Polyproline II helix	trans	-76.1	134.3	173.5	-65.2	164.8	0	0	0	110.1
107	G	28.5	Very low	34.8	Very low	76 Å²	76	143.2 Å²	143.2	78%	0.784	79%	0.792	S	S	*	*			trans	-130.1	117.4	162.6	0	0	0	0	0	109.3
108	H	36.7	Very low	35.1	Very low	170 Å²	170	142.2 Å²	142.2	79%	0.787	79%	0.788	S	S	*	*			trans	-83.3	140	176.7	-83.7	-89.3	0	0	0	111.6
109	T	31.1	Very low	35.4	Very low	130 Å²	130	144.7 Å²	144.7	80%	0.798	79%	0.787	S	S	*	*				-173.9	118.9	125.1	44.2	0	0	0	0	111.2
110	H	33.5	Very low	35.1	Very low	170 Å²	170	145.9 Å²	145.9	79%	0.787	79%	0.788	S	S	*	*			trans	37.9	137.8	152.1	-80.4	-89.6	0	0	0	120.4
111	D	30.9	Very low	35.2	Very low	124 Å²	124	148.5 Å²	148.5	66%	0.663	79%	0.787	S	S	*	*			cis	-165.9	177.3	8.2	-144.8	-29.3	0	0	0	107.8
112	D	29.6	Very low	35.5	Very low	140 Å²	140	147 Å²	147	75%	0.749	77%	0.774	S	S	*	*			trans	98.3	62.2	168.1	-60.1	-21.8	0	0	0	118.2	F114	D112-F114 PolarHBondContact O-N 2.92Å
113	M	40.8	Very low	35.9	Very low	153 Å²	153	148 Å²	148	75%	0.754	78%	0.775	S	S	*	*				37.6	78	106.4	-160.4	179.3	79.6	0	0	117.4
114	F	39.7	Very low	36.1	Very low	189 Å²	189	150.7 Å²	150.7	83%	0.829	78%	0.78	S	S	*	*			trans	179.9	99.9	145.5	-92.5	-71	0	0	0	107.2	D112	D112-F114 PolarHBondContact O-N 2.92Å
115	T	39.1	Very low	36.5	Very low	143 Å²	143	154.2 Å²	154.2	88%	0.877	79%	0.786	S	S	*	*	S	Bend	trans	173	-13.1	151.7	30	0	0	0	0	115.2
116	H	34.1	Very low	37.2	Very low	193 Å²	193	151.4 Å²	151.4	89%	0.894	78%	0.783	S	S	*	*	S	Bend	trans	-105.8	80.3	179.3	-86	-81.9	0	0	0	112.1
117	S	39.8	Very low	37.5	Very low	104 Å²	104	147.8 Å²	147.8	73%	0.727	78%	0.783	S	S	*	*	S	Bend	trans	-162.5	20.1	168.5	-170.8	0	0	0	0	115.6
118	S	41.3	Very low	38.1	Very low	93 Å²	93	147.8 Å²	147.8	65%	0.65	78%	0.783	S	S	*	*	S	Bend	trans	-150	28.7	-176.5	-147.6	0	0	0	0	117
119	F	39.9	Very low	38.5	Very low	176 Å²	176	145.2 Å²	145.2	77%	0.772	78%	0.775	S	S	*	*	S	Bend	trans	-125.2	-26.3	177.9	-146.6	-101.1	0	0	0	115.2
120	D	32	Very low	39.7	Very low	158 Å²	158	144.4 Å²	144.4	85%	0.845	78%	0.775	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.5	-1.3	179.4	-64.4	-30.4	0	0	0	113.9
121	E	34	Very low	41.4	Very low	169 Å²	169	138.5 Å²	138.5	79%	0.79	75%	0.747	S	S	*	*	T	Hydrogen-bonded Turn	trans	-100.9	9.7	178.9	-95.7	-178.9	172.3	0	0	114.2
122	I	44.9	Very low	43.8	Very low	98 Å²	98	136.8 Å²	136.8	50%	0.503	74%	0.737	S	S	.	*	S	Bend	trans	-104.4	4.2	-178.5	-51.2	177.3	0	0	0	112.8
123	E	41.5	Very low	46.7	Very low	182 Å²	182	130.7 Å²	130.7	85%	0.85	71%	0.705	S	S	*	*	S	Bend	trans	-92.2	-2.3	172.2	-70.3	-166.3	161	0	0	114.2
124	E	41.9	Very low	49.2	Very low	178 Å²	178	128.4 Å²	128.4	83%	0.832	69%	0.692	S	S	*	*	S	Bend	trans	-113.7	71.4	179.1	-67.4	-168.4	172.2	0	0	112.5
125	E	41.4	Very low	51.8	Low	192 Å²	192	119.4 Å²	119.4	90%	0.897	65%	0.653	S	S	*	*			trans	-169	40.6	149.6	-110.2	-176.5	-159.6	0	0	111.2	G127	E125-G127 PolarHBondContact O-N 3.14Å
126	E	44.9	Very low	54.4	Low	193 Å²	193	114.3 Å²	114.3	90%	0.902	62%	0.623	S	S	*	*			trans	-79.6	67.5	164.1	-81.9	-163.8	159.3	0	0	110
127	G	41.5	Very low	57.3	Low	73 Å²	73	105.2 Å²	105.2	75%	0.753	58%	0.581	S	S	*	*			trans	-133.6	93.3	174.6	0	0	0	0	0	111.4	E125	E125-G127 PolarHBondContact O-N 3.14Å
128	G	41.4	Very low	59.8	Low	76 Å²	76	101.8 Å²	101.8	78%	0.784	56%	0.557	S	S	*	*	S	Bend	trans	105.4	66.4	149.6	0	0	0	0	0	118.5
129	D	44.9	Very low	62.1	Low	116 Å²	116	101.8 Å²	101.8	62%	0.62	55%	0.55	S	S	*	.				167.8	78.2	128	-111.1	-3.5	0	0	0	108.2	F131	D129-F131 HydrophobicContact CB-CE1 4.09Å; D129-F131 HydrophobicContact CB-CE2 4.03Å; D129-F131 HydrophobicContact CB-CZ 3.71Å; D129-F131 PolarHBondContact O-N 3.12Å; D129-F131 WeakPolarHBondContact OD2-CE1 3.4Å; D129-F131 WeakPolarHBondContact OD2-CZ 3.39Å
130	S	55.7	Low	64.4	Low	113 Å²	113	96.2 Å²	96.2	79%	0.79	53%	0.531	S	S	*	.			trans	-71.5	98.6	163.1	162.4	0	0	0	0	107.3	D132	S130-D132 VanDerWaalsContact C-N 3.33Å; S130-D132 PolarHBondContact O-N 3.43Å
131	F	69.4	Low	67	Low	46 Å²	46	92.7 Å²	92.7	20%	0.202	51%	0.51	C	S	.	.			trans	-66.7	94.7	169.9	-57.9	-68.9	0	0	0	108.7	D129 V133 M161 P241 L244	D129-F131 HydrophobicContact CB-CE1 4.09Å; D129-F131 HydrophobicContact CB-CE2 4.03Å; D129-F131 HydrophobicContact CB-CZ 3.71Å; D129-F131 PolarHBondContact O-N 3.12Å; D129-F131 WeakPolarHBondContact OD2-CE1 3.4Å; D129-F131 WeakPolarHBondContact OD2-CZ 3.39Å; F131-V133 PolarHBondContact O-N 2.98Å; F131-M161 HydrophobicContact CB-SD 3.81Å; F131-M161 HydrophobicContact CD1-CE 3.47Å; F131-M161 VanDerWaalsContact CD1-CE 3.47Å; F131-M161 HydrophobicContact CD1-SD 3.76Å; F131-M161 HydrophobicContact CE1-CE 4.13Å; F131-M161 HydrophobicContact CG-CE 4.43Å; F131-M161 HydrophobicContact CG-SD 4.25Å; F131-P241 HydrophobicContact CE2-CB 3.66Å; F131-P241 HydrophobicContact CZ-CB 4.02Å; F131-L244 HydrophobicContact CB-CD2 3.88Å; F131-L244 HydrophobicContact CD1-CD2 3.87Å; F131-L244 HydrophobicContact CG-CD2 3.83Å
132	D	82.8	Confident	69.6	Low	87 Å²	87	89.8 Å²	89.8	47%	0.465	50%	0.495	S	S	.	.			trans	-75.4	81.4	176.5	177.9	39.6	0	0	0	109.4	S130 T159 S160	S130-D132 VanDerWaalsContact C-N 3.33Å; S130-D132 PolarHBondContact O-N 3.43Å; D132-T159 VanDerWaalsContact O-CA 3.22Å; D132-T159 WeakPolarHBondContact O-CA 3.38Å; D132-T159 VanDerWaalsContact O-CB 3.32Å; D132-T159 WeakPolarHBondContact O-CB 3.33Å; D132-T159 PolarHBondContact O-OG1 3.46Å; D132-S160 WeakPolarHBondContact CB-OG 3.42Å; D132-S160 PolarHBondContact O-N 3.09Å; D132-S160 WeakPolarHBondContact OD2-CB 3.45Å; D132-S160 PolarHBondContact OD2-OG 2.89Å
133	V	90	Very high	71.6	Confident	12 Å²	12	87.3 Å²	87.3	7%	0.073	48%	0.482	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.6	119.7	173.1	-172.8	0	0	0	0	108.1	F131 I135 T157 M161 F164 V238 L244	F131-V133 PolarHBondContact O-N 2.98Å; V133-I135 HydrophobicContact CG1-CG1 4.2Å; V133-T157 HydrophobicContact CG1-CG2 3.96Å; V133-M161 HydrophobicContact CG2-CG 4.29Å; V133-M161 HydrophobicContact CG2-SD 3.33Å; V133-M161 WeakPolarHBondContact CG2-SD 3.38Å; V133-F164 HydrophobicContact CG2-CE2 4.18Å; V133-V238 HydrophobicContact CB-CB 4.49Å; V133-V238 HydrophobicContact CB-CG2 4.3Å; V133-V238 HydrophobicContact CG1-CB 4.21Å; V133-V238 HydrophobicContact CG1-CG2 4.05Å; V133-L244 HydrophobicContact CG2-CD1 4.37Å; V133-L244 HydrophobicContact CG2-CD2 4.2Å
134	H	92.4	Very high	73.6	Confident	105 Å²	105	81.2 Å²	81.2	49%	0.486	47%	0.468	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-113.6	125.9	173.1	-176.4	74.9	0	0	0	109.5	T157 K158	H134-T157 WeakPolarHBondContact O-CA 2.96Å; H134-K158 HydrophobicContact CB-CB 4.46Å; H134-K158 PolarHBondContact N-O 2.99Å; H134-K158 PolarHBondContact O-N 3.47Å
135	I	93.9	Very high	75.2	Confident	1 Å²	1	79.5 Å²	79.5	1%	0.005	46%	0.464	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-117.5	131.6	176.8	-62.3	177.5	0	0	0	108.5	V133 V137 V155 T156 T157 L234 M235 V238 L253	V133-I135 HydrophobicContact CG1-CG1 4.2Å; I135-V137 HydrophobicContact CG2-CG2 4.47Å; I135-V155 HydrophobicContact CG2-CG1 3.81Å; I135-T156 WeakPolarHBondContact CA-O 3.35Å; I135-T157 HydrophobicContact CG1-CG2 4.21Å; I135-L234 HydrophobicContact CD1-CB 4.01Å; I135-L234 HydrophobicContact CG2-CB 4.17Å; I135-L234 HydrophobicContact CG2-CD1 3.95Å; I135-M235 HydrophobicContact CB-CG 4.31Å; I135-M235 HydrophobicContact CB-SD 3.62Å; I135-M235 HydrophobicContact CG1-SD 4.2Å; I135-M235 PolarHBondContact N-SD 3.35Å; I135-V238 HydrophobicContact CD1-CB 4.24Å; I135-V238 HydrophobicContact CD1-CG1 3.49Å; I135-V238 VanDerWaalsContact CD1-CG1 3.49Å; I135-V238 HydrophobicContact CD1-CG2 3.76Å; I135-V238 HydrophobicContact CG1-CG2 4.35Å; I135-L253 HydrophobicContact CD1-CD1 4.24Å; I135-L253 HydrophobicContact CD1-CD2 3.73Å
136	S	94.5	Very high	76.8	Confident	35 Å²	35	72.9 Å²	72.9	25%	0.245	45%	0.447	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.8	136.1	167.9	63.2	0	0	0	0	110	T156 E231	S136-T156 PolarHBondContact N-O 2.94Å; S136-T156 PolarHBondContact O-N 3.35Å; S136-T156 WeakPolarHBondContact OG-CB 3.34Å; S136-E231 VanDerWaalsContact CA-OE2 3.3Å; S136-E231 WeakPolarHBondContact CA-OE2 3.47Å
137	V	94.4	Very high	78.1	Confident	2 Å²	2	72.3 Å²	72.3	1%	0.012	45%	0.447	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.8	122.3	174.3	-177.4	0	0	0	0	107.9	I135 Y153 K154 V155 R227 L230 E231 L234	I135-V137 HydrophobicContact CG2-CG2 4.47Å; V137-Y153 HydrophobicContact CG1-CD1 4.18Å; V137-Y153 HydrophobicContact CG1-CG 4.13Å; V137-K154 CarbonylContact C-O 3.58Å; V137-K154 WeakPolarHBondContact CA-O 3.49Å; V137-V155 HydrophobicContact CG2-CG2 4.36Å; V137-R227 HydrophobicContact CB-CG 4.2Å; V137-R227 HydrophobicContact CG1-CG 3.89Å; V137-R227 WeakPolarHBondContact O-CD 3.31Å; V137-R227 WeakPolarHBondContact O-CG 3.35Å; V137-R227 PolarHBondContact O-NH1 3.41Å; V137-L230 HydrophobicContact CG1-CB 4.45Å; V137-E231 HydrophobicContact CB-CB 4Å; V137-E231 HydrophobicContact CG2-CB 3.8Å; V137-E231 HydrophobicContact CG2-CG 4.34Å; V137-E231 PolarHBondContact N-OE2 2.99Å; V137-L234 HydrophobicContact CG2-CD1 4.23Å
138	S	92.9	Very high	79.7	Confident	33 Å²	33	75.7 Å²	75.7	23%	0.231	45%	0.448	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.6	-173.7	-176.3	72.8	0	0	0	0	111.9	K154	S138-K154 PolarHBondContact N-O 2.64Å; S138-K154 PolarHBondContact O-N 2.97Å
139	D	90.3	Very high	81.6	Confident	92 Å²	92	72.3 Å²	72.3	49%	0.492	41%	0.413	S	S	.	.	E	Extended strand (participates in β ladder)	trans	49.6	63.1	168.4	-48.7	-14.8	0	0	0	113	E141 K154	D139-E141 PolarHBondContact O-N 3.49Å; D139-E141 VanDerWaalsContact O-N 3.16Å; D139-K154 HydrophobicContact CB-CB 4Å; D139-K154 HydrophobicContact CB-CD 4.46Å; D139-K154 WeakPolarHBondContact OD2-CD 3.17Å; D139-K154 IonicContact OD2-NZ 3.23Å; D139-K154 PolarHBondContact OD2-NZ 3.45Å
140	P	88	Confident	83.3	Confident	59 Å²	59	71.6 Å²	71.6	38%	0.383	40%	0.402	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-63.9	115.9	174.5	28.3	-33.2	0	0	0	109.7	M151 A152 Y153 V223	P140-M151 VanDerWaalsContact C-SD 3.59Å; P140-M151 HydrophobicContact CB-CG 4.21Å; P140-M151 HydrophobicContact CB-SD 3.89Å; P140-A152 WeakPolarHBondContact CA-O 3.19Å; P140-Y153 HydrophobicContact CB-CD1 4.17Å; P140-Y153 HydrophobicContact CB-CE1 4.06Å; P140-V223 HydrophobicContact CB-CG1 3.39Å; P140-V223 HydrophobicContact CG-CG1 3.55Å
141	E	87.4	Confident	84.8	Confident	84 Å²	84	68.1 Å²	68.1	39%	0.393	37%	0.373	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.9	126.6	-176.2	-171.3	-174.5	171.6	0	0	110.5	D139 I143 M151 A152 K172	D139-E141 PolarHBondContact O-N 3.49Å; D139-E141 VanDerWaalsContact O-N 3.16Å; E141-I143 HydrophobicContact CB-CD1 4.4Å; E141-I143 VanDerWaalsContact CD-CD1 3.47Å; E141-I143 HydrophobicContact CG-CD1 3.78Å; E141-I143 PolarHBondContact O-N 2.79Å; E141-I143 WeakPolarHBondContact OE1-CD1 3.47Å; E141-M151 PolarHBondContact N-SD 3.49Å; E141-M151 VanDerWaalsContact N-SD 3.4Å; E141-M151 VanDerWaalsContact O-SD 3.4Å; E141-A152 PolarHBondContact N-O 2.94Å; E141-A152 PolarHBondContact O-N 3.49Å; E141-K172 IonicContact OE1-NZ 3.99Å; E141-K172 IonicContact OE2-NZ 2.64Å; E141-K172 PolarHBondContact OE2-NZ 3.42Å
142	K	87.1	Confident	85.7	Confident	109 Å²	109	66.1 Å²	66.1	47%	0.474	37%	0.366	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76	114.9	172.5	-176.8	-176.7	173.7	-172.5	0	108.8	A149 M151	K142-A149 HydrophobicContact CG-CB 4.33Å; K142-M151 HydrophobicContact CB-CE 4.5Å
143	I	86.4	Confident	86.2	Confident	46 Å²	46	62.1 Å²	62.1	24%	0.236	34%	0.344	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.4	129.8	177.1	-55.5	-62.3	0	0	0	109.8	E141 A149 Y150 A152	E141-I143 HydrophobicContact CB-CD1 4.4Å; E141-I143 VanDerWaalsContact CD-CD1 3.47Å; E141-I143 HydrophobicContact CG-CD1 3.78Å; E141-I143 PolarHBondContact O-N 2.79Å; E141-I143 WeakPolarHBondContact OE1-CD1 3.47Å; I143-A149 WeakPolarHBondContact O-CA 3.17Å; I143-Y150 HydrophobicContact CB-CD2 4.34Å; I143-Y150 HydrophobicContact CB-CE1 4.11Å; I143-Y150 HydrophobicContact CB-CE2 3.87Å; I143-Y150 HydrophobicContact CG1-CE2 4.19Å; I143-Y150 HydrophobicContact CG2-CE1 3.95Å; I143-Y150 HydrophobicContact CG2-CE2 4.28Å; I143-Y150 WeakPolarHBondContact CG2-OH 3.45Å; I143-Y150 PolarHBondContact N-O 3.39Å; I143-Y150 PolarHBondContact O-N 3Å; I143-A152 HydrophobicContact CG1-CB 3.71Å
144	G	84.6	Confident	86.5	Confident	53 Å²	53	65.3 Å²	65.3	55%	0.546	36%	0.357	S	S	.	.	S	Bend	trans	83.3	175.5	179.1	0	0	0	0	0	113.9	A149	G144-A149 WeakPolarHBondContact O-CB 3.15Å
145	D	75.5	Confident	86.6	Confident	143 Å²	143	60.3 Å²	60.3	77%	0.765	33%	0.334	S	S	*	.	S	Bend	trans	-124.9	157.6	-176.7	-164	14.8	0	0	0	112.1
146	G	74.4	Confident	86.8	Confident	52 Å²	52	61 Å²	61	54%	0.536	34%	0.338	S	S	.	.	G	3₁₀ helix	trans	63.6	-146	178.9	0	0	0	0	0	114.9	N148 A149	G146-N148 PolarHBondContact O-N 3.46Å; G146-A149 WeakPolarHBondContact O-CB 3.29Å; G146-A149 PolarHBondContact O-N 2.98Å
147	M	71.9	Confident	86.8	Confident	182 Å²	182	59.4 Å²	59.4	90%	0.897	33%	0.327	S	S	*	.	G	3₁₀ helix	trans	-63.9	-21.4	-175	-72.8	-176.3	165.5	0	0	114.3
148	N	75.8	Confident	86.8	Confident	143 Å²	143	64.3 Å²	64.3	77%	0.765	35%	0.348	S	S	*	.	G	3₁₀ helix	trans	-92.3	-0.7	-178.9	-70.6	-40.6	0	0	0	113.9	G146	G146-N148 PolarHBondContact O-N 3.46Å
149	A	80.5	Confident	86.8	Confident	6 Å²	6	63.1 Å²	63.1	5%	0.05	34%	0.34	C	S	.	.			trans	-63.8	140.1	177.8	0	0	0	0	0	111.9	K142 I143 G144 G146	K142-A149 HydrophobicContact CG-CB 4.33Å; I143-A149 WeakPolarHBondContact O-CA 3.17Å; G144-A149 WeakPolarHBondContact O-CB 3.15Å; G146-A149 WeakPolarHBondContact O-CB 3.29Å; G146-A149 PolarHBondContact O-N 2.98Å
150	Y	82.5	Confident	86.6	Confident	101 Å²	101	62.2 Å²	62.2	40%	0.396	34%	0.341	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-138.9	156.7	176.9	64.7	-90.6	0	0	0	111.5	I143 A152 R174	I143-Y150 HydrophobicContact CB-CD2 4.34Å; I143-Y150 HydrophobicContact CB-CE1 4.11Å; I143-Y150 HydrophobicContact CB-CE2 3.87Å; I143-Y150 HydrophobicContact CG1-CE2 4.19Å; I143-Y150 HydrophobicContact CG2-CE1 3.95Å; I143-Y150 HydrophobicContact CG2-CE2 4.28Å; I143-Y150 WeakPolarHBondContact CG2-OH 3.45Å; I143-Y150 PolarHBondContact N-O 3.39Å; I143-Y150 PolarHBondContact O-N 3Å; Y150-A152 HydrophobicContact CE2-CB 4.21Å; Y150-R174 HydrophobicContact CD2-CB 3.45Å; Y150-R174 VanDerWaalsContact CD2-CB 3.45Å; Y150-R174 HydrophobicContact CD2-CG 4.22Å; Y150-R174 HydrophobicContact CE2-CB 3.75Å; Y150-R174 HydrophobicContact CE2-CG 4.28Å; Y150-R174 HydrophobicContact CG-CB 4.42Å
151	M	85.4	Confident	86.5	Confident	39 Å²	39	60.9 Å²	60.9	19%	0.192	33%	0.329	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-88.3	123.9	173.6	-165.1	64.6	70.3	0	0	109.7	P140 E141 K142 Y153 R174 V210 V223	P140-M151 VanDerWaalsContact C-SD 3.59Å; P140-M151 HydrophobicContact CB-CG 4.21Å; P140-M151 HydrophobicContact CB-SD 3.89Å; E141-M151 PolarHBondContact N-SD 3.49Å; E141-M151 VanDerWaalsContact N-SD 3.4Å; E141-M151 VanDerWaalsContact O-SD 3.4Å; K142-M151 HydrophobicContact CB-CE 4.5Å; M151-Y153 HydrophobicContact CB-CE2 4.19Å; M151-Y153 HydrophobicContact CG-CE1 4.07Å; M151-Y153 HydrophobicContact CG-CE2 3.98Å; M151-Y153 WeakPolarHBondContact CG-OH 3.42Å; M151-R174 WeakPolarHBondContact O-CA 3.42Å; M151-V210 HydrophobicContact CE-CG1 3.88Å; M151-V223 HydrophobicContact CE-CG2 4.35Å
152	A	90.1	Very high	86.4	Confident	5 Å²	5	62.8 Å²	62.8	4%	0.041	35%	0.352	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.5	150.7	168.6	0	0	0	0	0	109.8	P140 E141 I143 Y150 R173	P140-A152 WeakPolarHBondContact CA-O 3.19Å; E141-A152 PolarHBondContact N-O 2.94Å; E141-A152 PolarHBondContact O-N 3.49Å; I143-A152 HydrophobicContact CG1-CB 3.71Å; Y150-A152 HydrophobicContact CE2-CB 4.21Å; A152-R173 CarbonylContact C-O 3.58Å; A152-R173 WeakPolarHBondContact CA-O 3.4Å
153	Y	93.1	Very high	86.4	Confident	2 Å²	2	61.7 Å²	61.7	1%	0.008	35%	0.351	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-127.8	140.9	178.2	-54.3	-93.6	0	0	0	108.4	V137 P140 M151 V155 K172 R173 F175 R226 R227 L230	V137-Y153 HydrophobicContact CG1-CD1 4.18Å; V137-Y153 HydrophobicContact CG1-CG 4.13Å; P140-Y153 HydrophobicContact CB-CD1 4.17Å; P140-Y153 HydrophobicContact CB-CE1 4.06Å; M151-Y153 HydrophobicContact CB-CE2 4.19Å; M151-Y153 HydrophobicContact CG-CE1 4.07Å; M151-Y153 HydrophobicContact CG-CE2 3.98Å; M151-Y153 WeakPolarHBondContact CG-OH 3.42Å; Y153-V155 PolarHBondContact O-N 3.03Å; Y153-K172 WeakPolarHBondContact O-CA 3.33Å; Y153-R173 PolarHBondContact N-O 3.27Å; Y153-R173 PolarHBondContact O-N 3.23Å; Y153-F175 HydrophobicContact CE2-CB 4.41Å; Y153-R226 WeakPolarHBondContact OH-CD 3.19Å; Y153-R227 HydrophobicContact CD1-CB 4.34Å; Y153-R227 HydrophobicContact CD1-CG 4.39Å; Y153-R227 HydrophobicContact CE1-CB 4.25Å; Y153-L230 HydrophobicContact CD1-CD1 4.25Å; Y153-L230 HydrophobicContact CD2-CD1 3.79Å; Y153-L230 HydrophobicContact CE1-CD1 4.14Å; Y153-L230 HydrophobicContact CE2-CD1 3.71Å; Y153-L230 HydrophobicContact CG-CD1 4.09Å
154	K	94.8	Very high	86.4	Confident	79 Å²	79	60.2 Å²	60.2	34%	0.343	34%	0.343	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-81.7	115.2	171.1	-175.4	-175.2	178.2	-176.6	0	109	V137 S138 D139 A170	V137-K154 CarbonylContact C-O 3.58Å; V137-K154 WeakPolarHBondContact CA-O 3.49Å; S138-K154 PolarHBondContact N-O 2.64Å; S138-K154 PolarHBondContact O-N 2.97Å; D139-K154 HydrophobicContact CB-CB 4Å; D139-K154 HydrophobicContact CB-CD 4.46Å; D139-K154 WeakPolarHBondContact OD2-CD 3.17Å; D139-K154 IonicContact OD2-NZ 3.23Å; D139-K154 PolarHBondContact OD2-NZ 3.45Å; K154-A170 HydrophobicContact CG-CB 4.07Å
155	V	96.3	Very high	86.5	Confident	0 Å²	0	66.4 Å²	66.4	0%	0	36%	0.355	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.3	108.4	173.5	-176.6	0	0	0	0	107.2	I135 V137 Y153 A170 V171 R173 F178 L234 L253	I135-V155 HydrophobicContact CG2-CG1 3.81Å; V137-V155 HydrophobicContact CG2-CG2 4.36Å; Y153-V155 PolarHBondContact O-N 3.03Å; V155-A170 CarbonylContact O-C 3.56Å; V155-A170 VanDerWaalsContact O-CA 3.23Å; V155-A170 WeakPolarHBondContact O-CA 3.2Å; V155-V171 HydrophobicContact CB-CG2 4.07Å; V155-V171 PolarHBondContact N-O 2.96Å; V155-V171 PolarHBondContact O-N 3.41Å; V155-R173 HydrophobicContact CG2-CB 4.02Å; V155-R173 HydrophobicContact CG2-CG 3.84Å; V155-F178 HydrophobicContact CG2-CE1 4.5Å; V155-F178 HydrophobicContact CG2-CZ 3.84Å; V155-L234 HydrophobicContact CG1-CD1 3.64Å; V155-L234 HydrophobicContact CG2-CD1 4.23Å; V155-L253 HydrophobicContact CG1-CD2 4.24Å
156	T	96	Very high	87.1	Confident	17 Å²	17	65.4 Å²	65.4	10%	0.104	35%	0.345	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.3	129.9	176.9	-53.2	0	0	0	0	108.7	I135 S136 F169 A170	I135-T156 WeakPolarHBondContact CA-O 3.35Å; S136-T156 PolarHBondContact N-O 2.94Å; S136-T156 PolarHBondContact O-N 3.35Å; S136-T156 WeakPolarHBondContact OG-CB 3.34Å; T156-F169 WeakPolarHBondContact CA-O 3.18Å; T156-A170 HydrophobicContact CG2-CB 4.45Å
157	T	95.4	Very high	87.8	Confident	0 Å²	0	72.4 Å²	72.4	0%	0	36%	0.356	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-120.2	127.2	-179.3	-53.1	0	0	0	0	109.1	V133 H134 I135 D168 F169	V133-T157 HydrophobicContact CG1-CG2 3.96Å; H134-T157 WeakPolarHBondContact O-CA 2.96Å; I135-T157 HydrophobicContact CG1-CG2 4.21Å; T157-D168 WeakPolarHBondContact O-CA 3.23Å; T157-F169 VanDerWaalsContact CB-CZ 3.5Å; T157-F169 HydrophobicContact CG2-CE1 4.06Å; T157-F169 HydrophobicContact CG2-CE2 4.19Å; T157-F169 HydrophobicContact CG2-CZ 3.62Å; T157-F169 PolarHBondContact N-O 2.66Å; T157-F169 PolarHBondContact O-N 2.75Å; T157-F169 VanDerWaalsContact O-N 3.11Å
158	K	94.2	Very high	88.8	Confident	105 Å²	105	68 Å²	68	46%	0.457	34%	0.336	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-119	128	172.9	-62.8	-173.3	-178.6	-168.4	0	109.2	H134 R167 D168	H134-K158 HydrophobicContact CB-CB 4.46Å; H134-K158 PolarHBondContact N-O 2.99Å; H134-K158 PolarHBondContact O-N 3.47Å; K158-R167 CarbonylContact C-O 3.55Å; K158-R167 VanDerWaalsContact CA-O 3.29Å; K158-R167 WeakPolarHBondContact CA-O 3.22Å; K158-D168 WeakPolarHBondContact CE-OD2 3.18Å; K158-D168 IonicContact NZ-OD2 3.39Å
159	T	92.5	Very high	89.7	Confident	9 Å²	9	62.1 Å²	62.1	6%	0.055	30%	0.303	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-156.1	147.4	-176.4	-175.9	0	0	0	0	112.7	D132 M161 F164 R167	D132-T159 VanDerWaalsContact O-CA 3.22Å; D132-T159 WeakPolarHBondContact O-CA 3.38Å; D132-T159 VanDerWaalsContact O-CB 3.32Å; D132-T159 WeakPolarHBondContact O-CB 3.33Å; D132-T159 PolarHBondContact O-OG1 3.46Å; T159-M161 WeakPolarHBondContact OG1-CB 3.41Å; T159-M161 WeakPolarHBondContact OG1-CG 3.38Å; T159-M161 PolarHBondContact OG1-N 2.91Å; T159-F164 HydrophobicContact CG2-CB 3.92Å; T159-F164 HydrophobicContact CG2-CD2 3.41Å; T159-F164 VanDerWaalsContact CG2-CD2 3.41Å; T159-F164 HydrophobicContact CG2-CE2 4.06Å; T159-F164 HydrophobicContact CG2-CG 3.77Å; T159-R167 PolarHBondContact N-O 3.47Å; T159-R167 WeakPolarHBondContact O-CA 3.36Å; T159-R167 WeakPolarHBondContact O-CB 3.33Å
160	S	87.4	Confident	90.4	Very high	73 Å²	73	64.2 Å²	64.2	51%	0.51	32%	0.321	S	S	.	.			trans	-95.3	0.1	169.6	56	0	0	0	0	113.2	D132	D132-S160 WeakPolarHBondContact CB-OG 3.42Å; D132-S160 PolarHBondContact O-N 3.09Å; D132-S160 WeakPolarHBondContact OD2-CB 3.45Å; D132-S160 PolarHBondContact OD2-OG 2.89Å
161	M	85.5	Confident	91	Very high	30 Å²	30	59.9 Å²	59.9	15%	0.148	31%	0.305	C	S	.	.			trans	-73.7	134.8	-176.3	-65.9	-178.6	58.8	0	0	112.7	F131 V133 T159 L163 F164 L244	F131-M161 HydrophobicContact CB-SD 3.81Å; F131-M161 HydrophobicContact CD1-CE 3.47Å; F131-M161 VanDerWaalsContact CD1-CE 3.47Å; F131-M161 HydrophobicContact CD1-SD 3.76Å; F131-M161 HydrophobicContact CE1-CE 4.13Å; F131-M161 HydrophobicContact CG-CE 4.43Å; F131-M161 HydrophobicContact CG-SD 4.25Å; V133-M161 HydrophobicContact CG2-CG 4.29Å; V133-M161 HydrophobicContact CG2-SD 3.33Å; V133-M161 WeakPolarHBondContact CG2-SD 3.38Å; T159-M161 WeakPolarHBondContact OG1-CB 3.41Å; T159-M161 WeakPolarHBondContact OG1-CG 3.38Å; T159-M161 PolarHBondContact OG1-N 2.91Å; M161-L163 HydrophobicContact CE-CB 4.4Å; M161-L163 HydrophobicContact CE-CD1 3.45Å; M161-L163 VanDerWaalsContact CE-CD1 3.45Å; M161-L163 HydrophobicContact CE-CG 4.41Å; M161-L163 PolarHBondContact O-N 3.36Å; M161-F164 HydrophobicContact CB-CD2 4.09Å; M161-F164 HydrophobicContact CB-CE2 4.42Å; M161-F164 PolarHBondContact O-N 3.18Å; M161-L244 HydrophobicContact CE-CD2 3.66Å; M161-L244 HydrophobicContact SD-CD2 3.73Å
162	S	85.6	Confident	91.3	Very high	125 Å²	125	63.8 Å²	63.8	87%	0.874	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.1	-6.4	176.9	59.7	0	0	0	0	114.5	F164	S162-F164 PolarHBondContact O-N 3.05Å
163	L	86.6	Confident	91.5	Very high	85 Å²	85	63.8 Å²	63.8	45%	0.445	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	-69.9	-21.9	174.9	-83.3	161.4	0	0	0	112.6	M161 K245	M161-L163 HydrophobicContact CE-CB 4.4Å; M161-L163 HydrophobicContact CE-CD1 3.45Å; M161-L163 VanDerWaalsContact CE-CD1 3.45Å; M161-L163 HydrophobicContact CE-CG 4.41Å; M161-L163 PolarHBondContact O-N 3.36Å; L163-K245 HydrophobicContact CD1-CG 4.31Å
164	F	86.4	Confident	91.3	Very high	15 Å²	15	65.9 Å²	65.9	7%	0.066	33%	0.328	C	S	.	.	S	Bend	trans	-101.1	146.8	179	-62.5	-84.9	0	0	0	111.3	V133 T159 M161 S162 Q166 F169 L244 L250 L253 E254	V133-F164 HydrophobicContact CG2-CE2 4.18Å; T159-F164 HydrophobicContact CG2-CB 3.92Å; T159-F164 HydrophobicContact CG2-CD2 3.41Å; T159-F164 VanDerWaalsContact CG2-CD2 3.41Å; T159-F164 HydrophobicContact CG2-CE2 4.06Å; T159-F164 HydrophobicContact CG2-CG 3.77Å; M161-F164 HydrophobicContact CB-CD2 4.09Å; M161-F164 HydrophobicContact CB-CE2 4.42Å; M161-F164 PolarHBondContact O-N 3.18Å; S162-F164 PolarHBondContact O-N 3.05Å; F164-Q166 VanDerWaalsContact C-N 3.31Å; F164-Q166 PolarHBondContact O-N 3.46Å; F164-F169 HydrophobicContact CB-CE1 4.16Å; F164-F169 HydrophobicContact CD1-CE1 4.01Å; F164-F169 AromaticContact CD1-CZ 3.65Å; F164-F169 HydrophobicContact CD1-CZ 3.65Å; F164-F169 HydrophobicContact CE1-CZ 4.1Å; F164-F169 HydrophobicContact CG-CE1 4.27Å; F164-F169 HydrophobicContact CG-CZ 4.34Å; F164-L244 HydrophobicContact CE2-CD1 4.31Å; F164-L244 HydrophobicContact CZ-CD1 3.95Å; F164-L250 HydrophobicContact CD1-CD2 4.4Å; F164-L250 HydrophobicContact CE1-CD2 3.64Å; F164-L250 HydrophobicContact CE2-CD2 4.48Å; F164-L250 HydrophobicContact CZ-CD2 3.7Å; F164-L253 HydrophobicContact CE1-CB 4.34Å; F164-L253 HydrophobicContact CE1-CD1 3.93Å; F164-L253 HydrophobicContact CZ-CD1 4.05Å; F164-E254 WeakPolarHBondContact CA-OE1 3.49Å; F164-E254 HydrophobicContact CD1-CG 3.97Å
165	K	85.8	Confident	91	Very high	183 Å²	183	62.8 Å²	62.8	80%	0.796	31%	0.314	S	S	*	.	S	Bend	trans	-69.4	-31.8	179.2	-64.6	173.9	-173.3	165.5	0	112.3	E254	K165-E254 PolarHBondContact N-OE1 3.04Å; K165-E254 IonicContact NZ-OE2 3.64Å
166	Q	88.3	Confident	90.5	Very high	122 Å²	122	64 Å²	64	57%	0.57	32%	0.322	S	S	*	.			trans	-130.9	149.4	-175.9	-65.8	-178.2	-9.5	0	0	109.7	F164 F169	F164-Q166 VanDerWaalsContact C-N 3.31Å; F164-Q166 PolarHBondContact O-N 3.46Å; Q166-F169 HydrophobicContact CB-CB 4.37Å; Q166-F169 HydrophobicContact CB-CD1 3.98Å; Q166-F169 WeakPolarHBondContact O-CD1 3.42Å; Q166-F169 WeakPolarHBondContact O-CE1 3.21Å
167	R	89.4	Confident	90.3	Very high	200 Å²	200	64 Å²	64	76%	0.755	32%	0.322	S	S	*	.	S	Bend	trans	-83.8	-22.8	179.2	-66.4	-174.3	177.6	-178	-1.7	113.6	K158 T159	K158-R167 CarbonylContact C-O 3.55Å; K158-R167 VanDerWaalsContact CA-O 3.29Å; K158-R167 WeakPolarHBondContact CA-O 3.22Å; T159-R167 PolarHBondContact N-O 3.47Å; T159-R167 WeakPolarHBondContact O-CA 3.36Å; T159-R167 WeakPolarHBondContact O-CB 3.33Å
168	D	94	Very high	90.1	Very high	89 Å²	89	64.1 Å²	64.1	48%	0.476	32%	0.322	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-142.7	120.5	177.5	-166.5	-20.7	0	0	0	107.5	T157 K158	T157-D168 WeakPolarHBondContact O-CA 3.23Å; K158-D168 WeakPolarHBondContact CE-OD2 3.18Å; K158-D168 IonicContact NZ-OD2 3.39Å
169	F	94.2	Very high	89.9	Confident	19 Å²	19	59.3 Å²	59.3	8%	0.083	30%	0.301	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-154.2	158.6	179.6	57.7	-87.5	0	0	0	110.6	T156 T157 F164 Q166 L253 E254	T156-F169 WeakPolarHBondContact CA-O 3.18Å; T157-F169 VanDerWaalsContact CB-CZ 3.5Å; T157-F169 HydrophobicContact CG2-CE1 4.06Å; T157-F169 HydrophobicContact CG2-CE2 4.19Å; T157-F169 HydrophobicContact CG2-CZ 3.62Å; T157-F169 PolarHBondContact N-O 2.66Å; T157-F169 PolarHBondContact O-N 2.75Å; T157-F169 VanDerWaalsContact O-N 3.11Å; F164-F169 HydrophobicContact CB-CE1 4.16Å; F164-F169 HydrophobicContact CD1-CE1 4.01Å; F164-F169 AromaticContact CD1-CZ 3.65Å; F164-F169 HydrophobicContact CD1-CZ 3.65Å; F164-F169 HydrophobicContact CE1-CZ 4.1Å; F164-F169 HydrophobicContact CG-CE1 4.27Å; F164-F169 HydrophobicContact CG-CZ 4.34Å; Q166-F169 HydrophobicContact CB-CB 4.37Å; Q166-F169 HydrophobicContact CB-CD1 3.98Å; Q166-F169 WeakPolarHBondContact O-CD1 3.42Å; Q166-F169 WeakPolarHBondContact O-CE1 3.21Å; F169-L253 HydrophobicContact CE2-CB 4.03Å; F169-L253 WeakPolarHBondContact CE2-O 3.24Å; F169-L253 HydrophobicContact CZ-CB 4.34Å; F169-E254 HydrophobicContact CE2-CG 4.06Å; F169-E254 HydrophobicContact CZ-CG 3.99Å
170	A	94.7	Very high	89.8	Confident	50 Å²	50	59.4 Å²	59.4	41%	0.413	30%	0.304	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-137.3	142.5	178	0	0	0	0	0	111.9	K154 V155 T156	K154-A170 HydrophobicContact CG-CB 4.07Å; V155-A170 CarbonylContact O-C 3.56Å; V155-A170 VanDerWaalsContact O-CA 3.23Å; V155-A170 WeakPolarHBondContact O-CA 3.2Å; T156-A170 HydrophobicContact CG2-CB 4.45Å
171	V	94.6	Very high	90.1	Very high	10 Å²	10	56.2 Å²	56.2	6%	0.061	28%	0.282	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-130.4	150.5	176.4	-65.8	0	0	0	0	110.6	V155 R173 L253	V155-V171 HydrophobicContact CB-CG2 4.07Å; V155-V171 PolarHBondContact N-O 2.96Å; V155-V171 PolarHBondContact O-N 3.41Å; V171-R173 HydrophobicContact CG2-CG 4.15Å; V171-L253 WeakPolarHBondContact CG1-O 3.27Å; V171-L253 VanDerWaalsContact CG2-O 3.23Å; V171-L253 WeakPolarHBondContact CG2-O 3.5Å
172	K	93.4	Very high	90.4	Very high	122 Å²	122	56.4 Å²	56.4	53%	0.53	28%	0.282	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.8	132.5	171.7	-67	-169.6	-179.1	-171.4	0	109.8	E141 Y153	E141-K172 IonicContact OE1-NZ 3.99Å; E141-K172 IonicContact OE2-NZ 2.64Å; E141-K172 PolarHBondContact OE2-NZ 3.42Å; Y153-K172 WeakPolarHBondContact O-CA 3.33Å
173	R	92.6	Very high	90.7	Very high	5 Å²	5	53 Å²	53	2%	0.019	26%	0.258	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-134.4	135.7	179.1	-63.6	-65	177.6	-118.8	9.1	110.5	A152 Y153 V155 V171 F178 F252 S255 L258	A152-R173 CarbonylContact C-O 3.58Å; A152-R173 WeakPolarHBondContact CA-O 3.4Å; Y153-R173 PolarHBondContact N-O 3.27Å; Y153-R173 PolarHBondContact O-N 3.23Å; V155-R173 HydrophobicContact CG2-CB 4.02Å; V155-R173 HydrophobicContact CG2-CG 3.84Å; V171-R173 HydrophobicContact CG2-CG 4.15Å; R173-F178 HydrophobicContact CB-CD2 4.3Å; R173-F178 HydrophobicContact CB-CE2 3.5Å; R173-F178 VanDerWaalsContact CB-CE2 3.5Å; R173-F178 HydrophobicContact CB-CZ 3.98Å; R173-F252 HydrophobicContact CB-CE2 4.45Å; R173-F252 HydrophobicContact CB-CZ 3.99Å; R173-F252 HydrophobicContact CG-CE1 3.99Å; R173-F252 HydrophobicContact CG-CE2 4.02Å; R173-F252 HydrophobicContact CG-CZ 3.58Å; R173-F252 PolarHBondContact NE-O 3.17Å; R173-F252 PolarHBondContact NH2-O 2.89Å; R173-S255 VanDerWaalsContact CZ-O 3.27Å; R173-S255 PolarHBondContact NH1-O 2.93Å; R173-S255 VanDerWaalsContact NH1-O 3.08Å; R173-S255 PolarHBondContact NH2-O 2.71Å; R173-L258 VanDerWaalsContact CZ-CD1 3.44Å; R173-L258 VanDerWaalsContact NE-CD1 3.33Å
174	R	90.3	Very high	91	Very high	46 Å²	46	53.4 Å²	53.4	17%	0.174	26%	0.256	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-92.3	158.4	169.2	57.4	171.1	-170.5	169.5	15	109.9	Y150 M151 S176 D177 F178	Y150-R174 HydrophobicContact CD2-CB 3.45Å; Y150-R174 VanDerWaalsContact CD2-CB 3.45Å; Y150-R174 HydrophobicContact CD2-CG 4.22Å; Y150-R174 HydrophobicContact CE2-CB 3.75Å; Y150-R174 HydrophobicContact CE2-CG 4.28Å; Y150-R174 HydrophobicContact CG-CB 4.42Å; M151-R174 WeakPolarHBondContact O-CA 3.42Å; R174-S176 VanDerWaalsContact CD-OG 3.27Å; R174-S176 WeakPolarHBondContact CD-OG 3.43Å; R174-S176 PolarHBondContact NE-OG 3.46Å; R174-S176 PolarHBondContact NH2-OG 3.11Å; R174-S176 PolarHBondContact O-N 3.21Å; R174-S176 VanDerWaalsContact O-N 3.1Å; R174-D177 VanDerWaalsContact CG-CG 3.4Å; R174-D177 WeakPolarHBondContact CG-OD1 3.48Å; R174-D177 WeakPolarHBondContact CG-OD2 3.31Å; R174-D177 IonicContact CZ-OD1 2.84Å; R174-D177 PolarHBondContact N-OD2 3.43Å; R174-D177 IonicContact NE-OD1 3.59Å; R174-D177 PolarHBondContact NE-OD1 2.62Å; R174-D177 IonicContact NE-OD2 3.24Å; R174-D177 IonicContact NH2-OD1 3.73Å; R174-D177 WeakPolarHBondContact O-CB 3.32Å; R174-D177 PolarHBondContact O-N 2.8Å; R174-F178 VanDerWaalsContact O-CD2 3.3Å; R174-F178 WeakPolarHBondContact O-CD2 3.48Å
175	F	86.9	Confident	91.4	Very high	14 Å²	14	52.7 Å²	52.7	6%	0.061	25%	0.253	C	S	.	.	H	α-helix	trans	-51.4	-38.9	-177.7	-179.8	-101	0	0	0	114.4	Y153 D177 F178 L179 P200 K202 M207 R226 L230	Y153-F175 HydrophobicContact CE2-CB 4.41Å; F175-D177 PolarHBondContact O-N 3.04Å; F175-F178 PolarHBondContact O-N 3.21Å; F175-L179 HydrophobicContact CD1-CD1 4.21Å; F175-L179 HydrophobicContact CE1-CD1 3.65Å; F175-L179 HydrophobicContact CE1-CD2 4.4Å; F175-L179 HydrophobicContact CE1-CG 4.11Å; F175-L179 HydrophobicContact CZ-CD1 4.25Å; F175-L179 HydrophobicContact CZ-CD2 4.2Å; F175-L179 HydrophobicContact CZ-CG 4.38Å; F175-L179 PolarHBondContact O-N 3.2Å; F175-P200 HydrophobicContact CE2-CB 4.19Å; F175-K202 HydrophobicContact CE1-CB 4.42Å; F175-K202 HydrophobicContact CE1-CD 3.8Å; F175-K202 HydrophobicContact CE1-CG 3.7Å; F175-K202 HydrophobicContact CZ-CG 4.19Å; F175-M207 HydrophobicContact CD1-CE 3.85Å; F175-M207 HydrophobicContact CE1-CE 3.97Å; F175-R226 HydrophobicContact CD2-CG 4.3Å; F175-L230 HydrophobicContact CD2-CD1 4.3Å; F175-L230 HydrophobicContact CD2-CD2 3.84Å; F175-L230 HydrophobicContact CD2-CG 4.47Å; F175-L230 HydrophobicContact CE2-CD2 4.12Å
176	S	87.1	Confident	91.7	Very high	24 Å²	24	45 Å²	45	17%	0.168	22%	0.224	C	C	.	.	H	α-helix	trans	-67.3	-22.3	178.6	45	0	0	0	0	114	R174 L179 G180 T264	R174-S176 VanDerWaalsContact CD-OG 3.27Å; R174-S176 WeakPolarHBondContact CD-OG 3.43Å; R174-S176 PolarHBondContact NE-OG 3.46Å; R174-S176 PolarHBondContact NH2-OG 3.11Å; R174-S176 PolarHBondContact O-N 3.21Å; R174-S176 VanDerWaalsContact O-N 3.1Å; S176-L179 PolarHBondContact O-N 3.33Å; S176-G180 PolarHBondContact O-N 2.81Å; S176-T264 WeakPolarHBondContact O-CG2 3.46Å
177	D	90.8	Very high	91.8	Very high	19 Å²	19	43.6 Å²	43.6	10%	0.102	23%	0.228	C	C	.	.	H	α-helix	trans	-71.1	-38.7	177.3	-52.3	-25.9	0	0	0	110.4	R174 F175 L179 G180 L181 F252 L258	R174-D177 VanDerWaalsContact CG-CG 3.4Å; R174-D177 WeakPolarHBondContact CG-OD1 3.48Å; R174-D177 WeakPolarHBondContact CG-OD2 3.31Å; R174-D177 IonicContact CZ-OD1 2.84Å; R174-D177 PolarHBondContact N-OD2 3.43Å; R174-D177 IonicContact NE-OD1 3.59Å; R174-D177 PolarHBondContact NE-OD1 2.62Å; R174-D177 IonicContact NE-OD2 3.24Å; R174-D177 IonicContact NH2-OD1 3.73Å; R174-D177 WeakPolarHBondContact O-CB 3.32Å; R174-D177 PolarHBondContact O-N 2.8Å; F175-D177 PolarHBondContact O-N 3.04Å; D177-L179 VanDerWaalsContact C-N 3.29Å; D177-L179 PolarHBondContact O-N 2.81Å; D177-G180 PolarHBondContact O-N 2.96Å; D177-G180 VanDerWaalsContact O-N 3.15Å; D177-L181 PolarHBondContact O-N 3.23Å; D177-F252 HydrophobicContact CB-CE2 3.86Å; D177-L258 HydrophobicContact CB-CD1 4.26Å
178	F	92.4	Very high	92.1	Very high	1 Å²	1	37.8 Å²	37.8	0%	0.004	21%	0.208	C	C	.	.	H	α-helix	trans	-60.7	-39.6	174	-65.9	-104.5	0	0	0	111.7	V155 R173 R174 F175 L181 H182 L230 Y233 L234 F252	V155-F178 HydrophobicContact CG2-CE1 4.5Å; V155-F178 HydrophobicContact CG2-CZ 3.84Å; R173-F178 HydrophobicContact CB-CD2 4.3Å; R173-F178 HydrophobicContact CB-CE2 3.5Å; R173-F178 VanDerWaalsContact CB-CE2 3.5Å; R173-F178 HydrophobicContact CB-CZ 3.98Å; R174-F178 VanDerWaalsContact O-CD2 3.3Å; R174-F178 WeakPolarHBondContact O-CD2 3.48Å; F175-F178 PolarHBondContact O-N 3.21Å; F178-L181 WeakPolarHBondContact O-CB 3.12Å; F178-L181 PolarHBondContact O-N 2.98Å; F178-H182 PolarHBondContact O-N 3.08Å; F178-L230 HydrophobicContact CB-CD2 3.92Å; F178-L230 HydrophobicContact CD1-CB 4.32Å; F178-L230 HydrophobicContact CD1-CD2 3.52Å; F178-L230 HydrophobicContact CD1-CG 4.46Å; F178-L230 HydrophobicContact CD2-CD2 3.77Å; F178-L230 HydrophobicContact CE1-CB 3.85Å; F178-L230 HydrophobicContact CE1-CD2 3.81Å; F178-L230 HydrophobicContact CE1-CG 4.3Å; F178-L230 HydrophobicContact CE2-CD1 4.24Å; F178-L230 HydrophobicContact CE2-CD2 4.08Å; F178-L230 HydrophobicContact CG-CD2 3.48Å; F178-L230 VanDerWaalsContact CG-CD2 3.48Å; F178-L230 HydrophobicContact CZ-CB 4.16Å; F178-L230 HydrophobicContact CZ-CD1 4.25Å; F178-L230 HydrophobicContact CZ-CD2 4.11Å; F178-L230 HydrophobicContact CZ-CG 4.41Å; F178-Y233 HydrophobicContact CB-CE1 4.47Å; F178-Y233 HydrophobicContact CD1-CD1 4.09Å; F178-Y233 HydrophobicContact CD1-CE1 4.33Å; F178-L234 HydrophobicContact CD1-CD1 4.27Å; F178-L234 HydrophobicContact CD1-CD2 4.19Å; F178-L234 HydrophobicContact CD1-CG 4.07Å; F178-L234 HydrophobicContact CE1-CD1 3.48Å; F178-L234 VanDerWaalsContact CE1-CD1 3.48Å; F178-L234 HydrophobicContact CE1-CD2 4.22Å; F178-L234 HydrophobicContact CE1-CG 3.73Å; F178-L234 HydrophobicContact CZ-CD1 4.29Å; F178-F252 HydrophobicContact CD1-CE1 4.33Å; F178-F252 AromaticContact CD1-CZ 3.74Å; F178-F252 HydrophobicContact CD1-CZ 3.74Å; F178-F252 HydrophobicContact CD2-CE2 4.48Å; F178-F252 AromaticContact CD2-CZ 3.98Å; F178-F252 HydrophobicContact CD2-CZ 3.98Å; F178-F252 HydrophobicContact CE1-CE1 4.21Å; F178-F252 AromaticContact CE1-CZ 3.85Å; F178-F252 HydrophobicContact CE1-CZ 3.85Å; F178-F252 HydrophobicContact CE2-CZ 4.04Å; F178-F252 HydrophobicContact CG-CE2 4.37Å; F178-F252 AromaticContact CG-CZ 3.82Å; F178-F252 HydrophobicContact CG-CZ 3.82Å; F178-F252 AromaticContact CZ-CZ 3.98Å; F178-F252 HydrophobicContact CZ-CZ 3.98Å
179	L	89.8	Confident	92.2	Very high	4 Å²	4	35.2 Å²	35.2	2%	0.021	19%	0.192	C	C	.	.	H	α-helix	trans	-69.9	-35.9	176	-59	-172.8	0	0	0	112.6	F175 S176 D177 L181 H182 S183 A199 K202 T264 L267	F175-L179 HydrophobicContact CD1-CD1 4.21Å; F175-L179 HydrophobicContact CE1-CD1 3.65Å; F175-L179 HydrophobicContact CE1-CD2 4.4Å; F175-L179 HydrophobicContact CE1-CG 4.11Å; F175-L179 HydrophobicContact CZ-CD1 4.25Å; F175-L179 HydrophobicContact CZ-CD2 4.2Å; F175-L179 HydrophobicContact CZ-CG 4.38Å; F175-L179 PolarHBondContact O-N 3.2Å; S176-L179 PolarHBondContact O-N 3.33Å; D177-L179 VanDerWaalsContact C-N 3.29Å; D177-L179 PolarHBondContact O-N 2.81Å; L179-L181 VanDerWaalsContact C-N 3.34Å; L179-H182 PolarHBondContact O-N 3.4Å; L179-S183 WeakPolarHBondContact O-CB 3.19Å; L179-S183 PolarHBondContact O-N 3.27Å; L179-A199 HydrophobicContact CD2-CB 3.54Å; L179-K202 HydrophobicContact CD1-CD 3.93Å; L179-K202 HydrophobicContact CD1-CG 3.98Å; L179-T264 HydrophobicContact CB-CG2 4.24Å; L179-L267 HydrophobicContact CB-CD1 4.08Å; L179-L267 WeakPolarHBondContact O-CD1 3.49Å
180	G	90.2	Very high	92.1	Very high	11 Å²	11	36 Å²	36	11%	0.113	20%	0.197	C	C	.	.	H	α-helix	trans	-59	-47.9	171.5	0	0	0	0	0	111	S176 D177 S183 K184	S176-G180 PolarHBondContact O-N 2.81Å; D177-G180 PolarHBondContact O-N 2.96Å; D177-G180 VanDerWaalsContact O-N 3.15Å; G180-S183 WeakPolarHBondContact O-CB 3.17Å; G180-S183 PolarHBondContact O-N 2.86Å; G180-K184 WeakPolarHBondContact O-CG 3.22Å; G180-K184 PolarHBondContact O-N 2.68Å; G180-K184 VanDerWaalsContact O-N 3.09Å
181	L	93	Very high	91.9	Very high	7 Å²	7	38.4 Å²	38.4	4%	0.037	20%	0.199	C	C	.	.	H	α-helix	trans	-57.1	-52.8	175.3	179.1	63.9	0	0	0	111.2	D177 F178 L179 S183 K184 L185 Y233 L234 D248 V249 F252	D177-L181 PolarHBondContact O-N 3.23Å; F178-L181 WeakPolarHBondContact O-CB 3.12Å; F178-L181 PolarHBondContact O-N 2.98Å; L179-L181 VanDerWaalsContact C-N 3.34Å; L181-S183 VanDerWaalsContact C-N 3.3Å; L181-S183 PolarHBondContact O-N 3.22Å; L181-K184 PolarHBondContact O-N 2.97Å; L181-K184 VanDerWaalsContact O-N 3.15Å; L181-L185 HydrophobicContact CD1-CD1 4.21Å; L181-L185 HydrophobicContact CD1-CG 4.24Å; L181-L185 HydrophobicContact CG-CD1 4.07Å; L181-L185 HydrophobicContact CG-CG 4.45Å; L181-L185 WeakPolarHBondContact O-CG 3.27Å; L181-L185 PolarHBondContact O-N 2.63Å; L181-Y233 HydrophobicContact CD2-CE1 4.39Å; L181-L234 HydrophobicContact CD2-CD2 4.2Å; L181-D248 HydrophobicContact CD1-CB 3.9Å; L181-V249 HydrophobicContact CD1-CG2 3.9Å; L181-V249 HydrophobicContact CD2-CG2 4.43Å; L181-F252 HydrophobicContact CB-CD2 4.16Å; L181-F252 HydrophobicContact CD1-CB 4.28Å; L181-F252 HydrophobicContact CD2-CB 4.11Å; L181-F252 HydrophobicContact CD2-CD1 3.98Å; L181-F252 HydrophobicContact CD2-CD2 4.11Å; L181-F252 HydrophobicContact CD2-CE1 4.48Å; L181-F252 HydrophobicContact CD2-CG 3.79Å
182	H	92.7	Very high	91.9	Very high	33 Å²	33	40.9 Å²	40.9	15%	0.153	21%	0.211	C	C	.	.	H	α-helix	trans	-54.9	-45	177.2	174.6	-85.5	0	0	0	112.3	F178 L179 K184 L185 A186 P197 A199 Y233	F178-H182 PolarHBondContact O-N 3.08Å; L179-H182 PolarHBondContact O-N 3.4Å; H182-K184 VanDerWaalsContact C-N 3.32Å; H182-K184 PolarHBondContact O-N 2.88Å; H182-L185 PolarHBondContact O-N 3.08Å; H182-A186 VanDerWaalsContact O-CB 3.29Å; H182-A186 WeakPolarHBondContact O-CB 3.37Å; H182-A186 PolarHBondContact O-N 3.33Å; H182-P197 PolarHBondContact CD2-O 2.69Å; H182-A199 HydrophobicContact CB-CB 3.84Å; H182-A199 PolarHBondContact CD2-N 3.35Å; H182-A199 VanDerWaalsContact CD2-N 3.3Å; H182-Y233 WeakPolarHBondContact CA-OH 3.33Å; H182-Y233 HydrophobicContact CB-CE2 4.4Å; H182-Y233 WeakPolarHBondContact CB-OH 3.4Å; H182-Y233 PolarHBondContact N-OH 3.37Å
183	S	91.1	Very high	91.9	Very high	54 Å²	54	35 Å²	35	38%	0.378	19%	0.186	S	C	.	.	H	α-helix	trans	-59.1	-43.6	179.2	-163.4	0	0	0	0	112.2	L179 G180 L181 S187	L179-S183 WeakPolarHBondContact O-CB 3.19Å; L179-S183 PolarHBondContact O-N 3.27Å; G180-S183 WeakPolarHBondContact O-CB 3.17Å; G180-S183 PolarHBondContact O-N 2.86Å; L181-S183 VanDerWaalsContact C-N 3.3Å; L181-S183 PolarHBondContact O-N 3.22Å; S183-S187 WeakPolarHBondContact O-CB 3.41Å; S183-S187 PolarHBondContact O-N 2.98Å
184	K	92.8	Very high	92.1	Very high	93 Å²	93	37.2 Å²	37.2	40%	0.404	19%	0.194	S	C	.	.	H	α-helix	trans	-65.7	-46.4	178.7	-67.8	-179	-178.9	-176.8	0	110.9	G180 L181 H182 S187 K188 D248	G180-K184 WeakPolarHBondContact O-CG 3.22Å; G180-K184 PolarHBondContact O-N 2.68Å; G180-K184 VanDerWaalsContact O-N 3.09Å; L181-K184 PolarHBondContact O-N 2.97Å; L181-K184 VanDerWaalsContact O-N 3.15Å; H182-K184 VanDerWaalsContact C-N 3.32Å; H182-K184 PolarHBondContact O-N 2.88Å; K184-S187 PolarHBondContact O-N 2.72Å; K184-K188 WeakPolarHBondContact O-CG 3.45Å; K184-K188 PolarHBondContact O-N 3Å; K184-D248 HydrophobicContact CD-CB 4.11Å; K184-D248 VanDerWaalsContact CD-OD1 3.22Å; K184-D248 WeakPolarHBondContact CD-OD1 3.42Å; K184-D248 WeakPolarHBondContact CD-OD2 3.44Å; K184-D248 IonicContact NZ-OD1 3.71Å; K184-D248 PolarHBondContact NZ-OD1 3.34Å
185	L	94.6	Very high	92.4	Very high	0 Å²	0	35.4 Å²	35.4	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62.4	-47.3	178	-66	-179.9	0	0	0	111.7	L181 H182 S187 K188 Y189 V196 T237 L243 D246 V249	L181-L185 HydrophobicContact CD1-CD1 4.21Å; L181-L185 HydrophobicContact CD1-CG 4.24Å; L181-L185 HydrophobicContact CG-CD1 4.07Å; L181-L185 HydrophobicContact CG-CG 4.45Å; L181-L185 WeakPolarHBondContact O-CG 3.27Å; L181-L185 PolarHBondContact O-N 2.63Å; H182-L185 PolarHBondContact O-N 3.08Å; L185-S187 VanDerWaalsContact C-N 3.32Å; L185-S187 PolarHBondContact O-N 3.03Å; L185-K188 PolarHBondContact O-N 3.4Å; L185-Y189 HydrophobicContact CB-CD2 4.36Å; L185-Y189 HydrophobicContact CD2-CD2 3.95Å; L185-Y189 HydrophobicContact CD2-CE2 3.71Å; L185-Y189 WeakPolarHBondContact O-CB 3.41Å; L185-Y189 WeakPolarHBondContact O-CD2 3.3Å; L185-Y189 PolarHBondContact O-N 3.47Å; L185-V196 HydrophobicContact CB-CG1 3.92Å; L185-T237 HydrophobicContact CD1-CG2 3.77Å; L185-L243 HydrophobicContact CD2-CD2 4.36Å; L185-D246 HydrophobicContact CD2-CB 4Å; L185-V249 HydrophobicContact CD1-CG2 3.87Å; L185-V249 HydrophobicContact CD2-CG2 3.99Å; L185-V249 HydrophobicContact CG-CG2 4.42Å
186	A	92.3	Very high	92.8	Very high	23 Å²	23	35 Å²	35	19%	0.19	19%	0.187	C	C	.	.	H	α-helix	trans	-58.6	-44.2	177	0	0	0	0	0	111.5	H182 K188 L190	H182-A186 VanDerWaalsContact O-CB 3.29Å; H182-A186 WeakPolarHBondContact O-CB 3.37Å; H182-A186 PolarHBondContact O-N 3.33Å; A186-K188 VanDerWaalsContact C-N 3.33Å; A186-K188 PolarHBondContact O-N 3.4Å; A186-L190 WeakPolarHBondContact O-CB 3.34Å; A186-L190 PolarHBondContact O-N 3.26Å; A186-L190 VanDerWaalsContact O-N 3.12Å
187	S	91.4	Very high	93.1	Very high	91 Å²	91	34.2 Å²	34.2	64%	0.636	18%	0.181	S	C	*	.	H	α-helix	trans	-62.2	-39.2	177.5	-170.3	0	0	0	0	112.7	S183 K184 L185 H191	S183-S187 WeakPolarHBondContact O-CB 3.41Å; S183-S187 PolarHBondContact O-N 2.98Å; K184-S187 PolarHBondContact O-N 2.72Å; L185-S187 VanDerWaalsContact C-N 3.32Å; L185-S187 PolarHBondContact O-N 3.03Å; S187-H191 PolarHBondContact O-CE1 3.22Å; S187-H191 VanDerWaalsContact O-CE1 3.3Å; S187-H191 PolarHBondContact O-ND1 2.91Å
188	K	94.6	Very high	92.9	Very high	79 Å²	79	34.4 Å²	34.4	34%	0.343	18%	0.184	S	C	.	.	H	α-helix	trans	-78.5	-38.5	-177.2	-73.7	171.7	168.2	-176.1	0	113.7	K184 L185 A186 H191 D246 D248	K184-K188 WeakPolarHBondContact O-CG 3.45Å; K184-K188 PolarHBondContact O-N 3Å; L185-K188 PolarHBondContact O-N 3.4Å; A186-K188 VanDerWaalsContact C-N 3.33Å; A186-K188 PolarHBondContact O-N 3.4Å; K188-H191 PolarHBondContact O-CE1 3.46Å; K188-H191 PolarHBondContact O-ND1 2.89Å; K188-D246 IonicContact NZ-OD1 2.68Å; K188-D246 PolarHBondContact NZ-OD1 3.41Å; K188-D246 IonicContact NZ-OD2 3.07Å; K188-D246 PolarHBondContact NZ-OD2 3.41Å; K188-D248 WeakPolarHBondContact CE-OD2 3.37Å; K188-D248 IonicContact NZ-OD2 3.94Å; K188-D248 PolarHBondContact NZ-OD2 3.15Å
189	Y	95.8	Very high	92.3	Very high	34 Å²	34	35.2 Å²	35.2	13%	0.133	19%	0.191	C	C	.	.	H	α-helix	trans	-114.5	-25.9	-161.2	-69.5	-70.7	0	0	0	114.3	L185 H191 I192 G193 Y194 I242 L243 D246	L185-Y189 HydrophobicContact CB-CD2 4.36Å; L185-Y189 HydrophobicContact CD2-CD2 3.95Å; L185-Y189 HydrophobicContact CD2-CE2 3.71Å; L185-Y189 WeakPolarHBondContact O-CB 3.41Å; L185-Y189 WeakPolarHBondContact O-CD2 3.3Å; L185-Y189 PolarHBondContact O-N 3.47Å; Y189-H191 PolarHBondContact O-N 3.44Å; Y189-I192 HydrophobicContact CD1-CD1 4.11Å; Y189-I192 WeakPolarHBondContact O-CG1 3.46Å; Y189-I192 PolarHBondContact O-N 3.37Å; Y189-G193 PolarHBondContact O-N 3.04Å; Y189-Y194 AromaticContact CD1-CD2 3.75Å; Y189-Y194 HydrophobicContact CD1-CD2 3.75Å; Y189-Y194 HydrophobicContact CD1-CE2 4.23Å; Y189-Y194 HydrophobicContact CD1-CG 4.39Å; Y189-Y194 HydrophobicContact CG-CD2 4.48Å; Y189-Y194 PolarHBondContact O-N 2.63Å; Y189-I242 HydrophobicContact CD1-CG2 4.18Å; Y189-I242 HydrophobicContact CE1-CG2 3.58Å; Y189-L243 HydrophobicContact CD1-CD2 4.37Å; Y189-L243 HydrophobicContact CD2-CD2 3.58Å; Y189-L243 HydrophobicContact CE2-CD2 3.91Å; Y189-L243 HydrophobicContact CG-CD2 3.84Å; Y189-D246 HydrophobicContact CE2-CB 4.08Å; Y189-D246 WeakPolarHBondContact CE2-OD2 3.41Å; Y189-D246 WeakPolarHBondContact OH-CB 2.99Å; Y189-D246 PolarHBondContact OH-OD2 2.92Å
190	L	92.6	Very high	91.5	Very high	37 Å²	37	35.6 Å²	35.6	19%	0.194	19%	0.193	C	C	.	.	G	3₁₀ helix	trans	-68.1	-39.8	-174.9	-168.2	68.1	0	0	0	112.2	A186 I192 G193 V397 H400	A186-L190 WeakPolarHBondContact O-CB 3.34Å; A186-L190 PolarHBondContact O-N 3.26Å; A186-L190 VanDerWaalsContact O-N 3.12Å; L190-I192 PolarHBondContact O-N 3.48Å; L190-G193 PolarHBondContact O-N 3.38Å; L190-V397 HydrophobicContact CD1-CG1 3.66Å; L190-H400 WeakPolarHBondContact CD2-CE1 3.46Å; L190-H400 VanDerWaalsContact CG-CE1 3.47Å; L190-H400 WeakPolarHBondContact CG-CE1 3.45Å
191	H	90.8	Very high	90.4	Very high	100 Å²	100	42.1 Å²	42.1	46%	0.463	22%	0.221	S	C	.	.	G	3₁₀ helix	trans	-72.5	-8	-179.5	73.1	-85.3	0	0	0	114.2	S187 K188 Y189	S187-H191 PolarHBondContact O-CE1 3.22Å; S187-H191 VanDerWaalsContact O-CE1 3.3Å; S187-H191 PolarHBondContact O-ND1 2.91Å; K188-H191 PolarHBondContact O-CE1 3.46Å; K188-H191 PolarHBondContact O-ND1 2.89Å; Y189-H191 PolarHBondContact O-N 3.44Å
192	I	94.4	Very high	88.9	Confident	61 Å²	61	43.9 Å²	43.9	31%	0.313	23%	0.228	S	C	.	.	G	3₁₀ helix	trans	-112.6	5.9	174.5	58.9	174.1	0	0	0	112.5	Y189 L190 Y194 T465	Y189-I192 HydrophobicContact CD1-CD1 4.11Å; Y189-I192 WeakPolarHBondContact O-CG1 3.46Å; Y189-I192 PolarHBondContact O-N 3.37Å; L190-I192 PolarHBondContact O-N 3.48Å; I192-Y194 HydrophobicContact CD1-CD2 3.74Å; I192-Y194 HydrophobicContact CD1-CE2 3.63Å; I192-Y194 HydrophobicContact CG1-CD2 3.7Å; I192-Y194 HydrophobicContact CG1-CE2 3.99Å; I192-T465 VanDerWaalsContact O-CB 3.27Å; I192-T465 WeakPolarHBondContact O-CB 3.38Å; I192-T465 WeakPolarHBondContact O-CG2 3.44Å; I192-T465 PolarHBondContact O-OG1 3.39Å
193	G	94.3	Very high	87.1	Confident	0 Å²	0	44.5 Å²	44.5	0%	0	24%	0.236	C	C	.	.	T	Hydrogen-bonded Turn	trans	98.7	9.5	166.8	0	0	0	0	0	117.1	Y189 L190	Y189-G193 PolarHBondContact O-N 3.04Å; L190-G193 PolarHBondContact O-N 3.38Å
194	Y	97.1	Very high	85.1	Confident	50 Å²	50	46 Å²	46	20%	0.196	24%	0.239	C	C	.	.			trans	-83.5	140.1	176	-68.8	-77.4	0	0	0	112.5	Y189 I192 V196 H240 I242 V397 T465 E469	Y189-Y194 AromaticContact CD1-CD2 3.75Å; Y189-Y194 HydrophobicContact CD1-CD2 3.75Å; Y189-Y194 HydrophobicContact CD1-CE2 4.23Å; Y189-Y194 HydrophobicContact CD1-CG 4.39Å; Y189-Y194 HydrophobicContact CG-CD2 4.48Å; Y189-Y194 PolarHBondContact O-N 2.63Å; I192-Y194 HydrophobicContact CD1-CD2 3.74Å; I192-Y194 HydrophobicContact CD1-CE2 3.63Å; I192-Y194 HydrophobicContact CG1-CD2 3.7Å; I192-Y194 HydrophobicContact CG1-CE2 3.99Å; Y194-V196 PolarHBondContact O-N 3.02Å; Y194-H240 AromaticContact CD1-CE1 3.74Å; Y194-H240 AromaticContact CD1-NE2 3.71Å; Y194-I242 HydrophobicContact CD1-CG1 4.5Å; Y194-I242 HydrophobicContact CE1-CB 4.2Å; Y194-I242 HydrophobicContact CE1-CG1 3.73Å; Y194-I242 HydrophobicContact CE1-CG2 4.3Å; Y194-I242 HydrophobicContact CE2-CG2 4.43Å; Y194-V397 WeakPolarHBondContact O-CG1 3.48Å; Y194-T465 HydrophobicContact CD1-CG2 3.91Å; Y194-T465 HydrophobicContact CD2-CG2 4.08Å; Y194-T465 HydrophobicContact CE1-CG2 3.8Å; Y194-T465 HydrophobicContact CE2-CG2 3.97Å; Y194-T465 HydrophobicContact CG-CG2 4.03Å; Y194-E469 HydrophobicContact CD1-CG 3.9Å
195	I	96.2	Very high	82.9	Confident	8 Å²	8	46.9 Å²	46.9	4%	0.041	25%	0.252	C	S	.	.			trans	-81.6	102.8	177.9	-60.7	162.8	0	0	0	108.5	P197 A393 V394 V397 E469 F473	I195-P197 WeakPolarHBondContact O-CD 3.29Å; I195-A393 HydrophobicContact CG2-CB 4.13Å; I195-V394 HydrophobicContact CD1-CG2 3.85Å; I195-V394 HydrophobicContact CG1-CG2 4.38Å; I195-V394 HydrophobicContact CG2-CG2 4.43Å; I195-V397 HydrophobicContact CG1-CG1 4.37Å; I195-V397 HydrophobicContact CG1-CG2 4.2Å; I195-E469 HydrophobicContact CD1-CB 3.82Å; I195-E469 HydrophobicContact CG1-CB 4.05Å; I195-E469 PolarHBondContact N-OE2 3.22Å; I195-E469 VanDerWaalsContact N-OE2 3.1Å; I195-F473 HydrophobicContact CD1-CB 3.86Å; I195-F473 HydrophobicContact CD1-CG 4.32Å
196	V	94.7	Very high	80.9	Confident	5 Å²	5	47.2 Å²	47.2	3%	0.03	26%	0.256	C	S	.	.	P	Polyproline II helix	trans	-82.2	123	174.4	-178.6	0	0	0	0	109.1	L185 Y194	L185-V196 HydrophobicContact CB-CG1 3.92Å; Y194-V196 PolarHBondContact O-N 3.02Å
197	P	92.9	Very high	79	Confident	8 Å²	8	48.7 Å²	48.7	5%	0.052	26%	0.259	C	S	.	.	P	Polyproline II helix	trans	-54.9	134.9	177.5	-26.6	34.7	0	0	0	111	H182 I195 A199 Y233 R236 L243	H182-P197 PolarHBondContact CD2-O 2.69Å; I195-P197 WeakPolarHBondContact O-CD 3.29Å; P197-A199 PolarHBondContact O-N 2.88Å; P197-Y233 HydrophobicContact CB-CD2 4.14Å; P197-Y233 HydrophobicContact CB-CE2 4.3Å; P197-Y233 WeakPolarHBondContact O-CE2 3.43Å; P197-R236 HydrophobicContact CB-CB 4.04Å; P197-R236 HydrophobicContact CG-CB 3.83Å; P197-L243 HydrophobicContact CG-CD1 4.44Å
198	P	86.4	Confident	77	Confident	24 Å²	24	48.3 Å²	48.3	16%	0.156	25%	0.253	C	S	.	.	P	Polyproline II helix	trans	-66.1	136.8	-178.1	28.1	-35.3	0	0	0	110.4	Y233 R389 L390	P198-Y233 WeakPolarHBondContact O-CD2 3.49Å; P198-R389 HydrophobicContact CB-CB 3.98Å; P198-R389 HydrophobicContact CG-CB 3.54Å; P198-L390 VanDerWaalsContact CD-CD2 3.46Å; P198-L390 HydrophobicContact CG-CD2 4.35Å; P198-L390 HydrophobicContact CG-CG 4.29Å
199	A	80.2	Confident	75	Confident	18 Å²	18	50.4 Å²	50.4	15%	0.149	26%	0.262	C	S	.	.	P	Polyproline II helix	trans	-65.5	148.5	172.2	0	0	0	0	0	111.7	L179 H182 P197	L179-A199 HydrophobicContact CD2-CB 3.54Å; H182-A199 HydrophobicContact CB-CB 3.84Å; H182-A199 PolarHBondContact CD2-N 3.35Å; H182-A199 VanDerWaalsContact CD2-N 3.3Å; P197-A199 PolarHBondContact O-N 2.88Å
200	P	74	Confident	73.1	Confident	11 Å²	11	50.6 Å²	50.6	7%	0.071	27%	0.267	C	S	.	.	P	Polyproline II helix	trans	-60.3	144.3	172.6	-20.8	32.8	0	0	0	111.6	F175 A229 L230	F175-P200 HydrophobicContact CE2-CB 4.19Å; P200-A229 HydrophobicContact CB-CB 3.96Å; P200-A229 HydrophobicContact CG-CB 4.12Å; P200-L230 HydrophobicContact CG-CD2 3.88Å; P200-L230 HydrophobicContact CG-CG 4.36Å
201	E	67.6	Low	71.1	Confident	149 Å²	149	54.3 Å²	54.3	70%	0.696	28%	0.282	S	S	*	.	P	Polyproline II helix	trans	-71.6	143.3	-176.1	-65.7	-169.9	169.7	0	0	113.1	S203	E201-S203 VanDerWaalsContact C-N 3.32Å; E201-S203 PolarHBondContact O-N 2.72Å
202	K	61.4	Low	69.3	Low	43 Å²	43	54.9 Å²	54.9	19%	0.187	29%	0.292	C	S	.	.			trans	-72.8	85.7	169.6	-61.4	-127.1	-168	160.3	0	109.7	F175 L179 I204 T264 S268	F175-K202 HydrophobicContact CE1-CB 4.42Å; F175-K202 HydrophobicContact CE1-CD 3.8Å; F175-K202 HydrophobicContact CE1-CG 3.7Å; F175-K202 HydrophobicContact CZ-CG 4.19Å; L179-K202 HydrophobicContact CD1-CD 3.93Å; L179-K202 HydrophobicContact CD1-CG 3.98Å; K202-I204 PolarHBondContact O-N 3.11Å; K202-T264 PolarHBondContact NZ-O 3.48Å; K202-S268 WeakPolarHBondContact CD-OG 3.32Å; K202-S268 WeakPolarHBondContact CE-OG 3.22Å; K202-S268 PolarHBondContact NZ-OG 2.81Å
203	S	53.8	Low	67	Low	46 Å²	46	54.7 Å²	54.7	32%	0.322	31%	0.305	S	S	.	.			trans	-70.5	105.1	166.8	174	0	0	0	0	109.8	E201 G206 M207 F222 R226	E201-S203 VanDerWaalsContact C-N 3.32Å; E201-S203 PolarHBondContact O-N 2.72Å; S203-G206 PolarHBondContact OG-N 3.13Å; S203-M207 WeakPolarHBondContact O-CG 3.33Å; S203-M207 PolarHBondContact O-N 3.33Å; S203-F222 VanDerWaalsContact CB-CE2 3.46Å; S203-F222 WeakPolarHBondContact OG-CE2 3.44Å; S203-R226 PolarHBondContact O-NH2 2.85Å
204	I	50	Low	64.7	Low	86 Å²	86	61.8 Å²	61.8	44%	0.441	34%	0.336	S	S	.	.	H	α-helix	trans	-71.7	-38.5	177.1	-60.8	173.3	0	0	0	109.8	K202 G206 M207 T208 A270	K202-I204 PolarHBondContact O-N 3.11Å; I204-G206 PolarHBondContact O-N 2.82Å; I204-M207 PolarHBondContact O-N 2.95Å; I204-T208 PolarHBondContact O-N 3.25Å; I204-T208 VanDerWaalsContact O-N 3.08Å; I204-T208 PolarHBondContact O-OG1 3.27Å; I204-A270 HydrophobicContact CD1-CB 4.37Å
205	V	46.5	Very low	62.5	Low	111 Å²	111	67.9 Å²	67.9	67%	0.673	37%	0.366	S	S	*	.	H	α-helix	trans	-62.3	-43.2	-179.6	-179.4	0	0	0	0	111.8	K209	V205-K209 PolarHBondContact O-N 2.85Å
206	G	51.8	Low	60.7	Low	8 Å²	8	71.5 Å²	71.5	8%	0.082	39%	0.385	C	S	.	.	H	α-helix	trans	-74.5	-29.1	175.7	0	0	0	0	0	113.7	S203 I204 K209 V210 F222	S203-G206 PolarHBondContact OG-N 3.13Å; I204-G206 PolarHBondContact O-N 2.82Å; G206-K209 PolarHBondContact O-N 3.32Å; G206-V210 WeakPolarHBondContact O-CG2 3.22Å; G206-V210 PolarHBondContact O-N 3.47Å; G206-V210 VanDerWaalsContact O-N 3.14Å; G206-F222 VanDerWaalsContact C-CZ 3.48Å; G206-F222 VanDerWaalsContact CA-CZ 3.45Å; G206-F222 WeakPolarHBondContact O-CE1 3.37Å
207	M	52.6	Low	58.9	Low	53 Å²	53	79.8 Å²	79.8	26%	0.261	42%	0.424	S	S	.	.	H	α-helix	trans	-66.7	-37.3	174.3	-78.8	-165.9	-157.8	0	0	112.7	F175 S203 I204 K211 R226	F175-M207 HydrophobicContact CD1-CE 3.85Å; F175-M207 HydrophobicContact CE1-CE 3.97Å; S203-M207 WeakPolarHBondContact O-CG 3.33Å; S203-M207 PolarHBondContact O-N 3.33Å; I204-M207 PolarHBondContact O-N 2.95Å; M207-K211 VanDerWaalsContact O-CB 3.31Å; M207-K211 WeakPolarHBondContact O-CB 3.45Å; M207-K211 VanDerWaalsContact O-CG 3.25Å; M207-K211 WeakPolarHBondContact O-CG 3.42Å; M207-K211 PolarHBondContact O-N 3.44Å; M207-K211 VanDerWaalsContact O-N 3.09Å; M207-R226 VanDerWaalsContact CE-NH2 3.3Å
208	T	50.1	Low	57.4	Low	83 Å²	83	82 Å²	82	51%	0.509	44%	0.439	S	S	.	.	H	α-helix	trans	-67.2	-40.7	176.9	-54.7	0	0	0	0	111.2	I204 K211 V212	I204-T208 PolarHBondContact O-N 3.25Å; I204-T208 VanDerWaalsContact O-N 3.08Å; I204-T208 PolarHBondContact O-OG1 3.27Å; T208-K211 PolarHBondContact O-N 3.25Å; T208-V212 HydrophobicContact CG2-CG2 4.38Å; T208-V212 WeakPolarHBondContact O-CG2 3.45Å; T208-V212 PolarHBondContact O-N 3.43Å
209	K	52.2	Low	56.3	Low	123 Å²	123	81.5 Å²	81.5	54%	0.535	44%	0.436	S	S	.	.	H	α-helix	trans	-63.9	-45.8	177	-71.2	-173.3	176	-175.2	0	112.9	V205 G206 K211 V212	V205-K209 PolarHBondContact O-N 2.85Å; G206-K209 PolarHBondContact O-N 3.32Å; K209-K211 VanDerWaalsContact C-N 3.28Å; K209-K211 PolarHBondContact O-N 3.07Å; K209-V212 PolarHBondContact O-N 3.48Å
210	V	55.2	Low	55.8	Low	38 Å²	38	85.7 Å²	85.7	23%	0.23	46%	0.456	C	S	.	.	H	α-helix	trans	-65.6	-30	176.8	175.4	0	0	0	0	112.3	M151 G206 F222 V223	M151-V210 HydrophobicContact CE-CG1 3.88Å; G206-V210 WeakPolarHBondContact O-CG2 3.22Å; G206-V210 PolarHBondContact O-N 3.47Å; G206-V210 VanDerWaalsContact O-N 3.14Å; V210-F222 HydrophobicContact CG2-CD1 3.71Å; V210-F222 HydrophobicContact CG2-CE1 4.19Å; V210-V223 HydrophobicContact CG2-CG2 4.03Å
211	K	51.9	Low	55.7	Low	116 Å²	116	88.4 Å²	88.4	50%	0.504	47%	0.468	S	S	.	.	H	α-helix	trans	-78.4	-23.6	179.8	-79.9	-175	171.6	-159.4	0	114.3	M207 T208 K209	M207-K211 VanDerWaalsContact O-CB 3.31Å; M207-K211 WeakPolarHBondContact O-CB 3.45Å; M207-K211 VanDerWaalsContact O-CG 3.25Å; M207-K211 WeakPolarHBondContact O-CG 3.42Å; M207-K211 PolarHBondContact O-N 3.44Å; M207-K211 VanDerWaalsContact O-N 3.09Å; T208-K211 PolarHBondContact O-N 3.25Å; K209-K211 VanDerWaalsContact C-N 3.28Å; K209-K211 PolarHBondContact O-N 3.07Å
212	V	52.2	Low	55.9	Low	112 Å²	112	82.9 Å²	82.9	68%	0.679	44%	0.442	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.3	-0.7	-175.7	-180	0	0	0	0	112.7	T208 K209 K214	T208-V212 HydrophobicContact CG2-CG2 4.38Å; T208-V212 WeakPolarHBondContact O-CG2 3.45Å; T208-V212 PolarHBondContact O-N 3.43Å; K209-V212 PolarHBondContact O-N 3.48Å; V212-K214 PolarHBondContact O-N 2.94Å
213	G	45.9	Very low	56.7	Low	57 Å²	57	81.7 Å²	81.7	59%	0.588	44%	0.438	S	S	*	.	T	Hydrogen-bonded Turn	trans	75.7	13.6	165.1	0	0	0	0	0	116.2	E215	G213-E215 PolarHBondContact O-N 3.42Å
214	K	45.7	Very low	58	Low	149 Å²	149	82.8 Å²	82.8	65%	0.648	44%	0.438	S	S	*	.			trans	-80.5	103.3	161.4	-88.3	-170.7	172	-173.3	0	108.6	V212 D216	V212-K214 PolarHBondContact O-N 2.94Å; K214-D216 PolarHBondContact O-N 3.4Å
215	E	51.2	Low	59.4	Low	177 Å²	177	82.4 Å²	82.4	83%	0.827	43%	0.433	S	S	*	.			trans	-71.8	64.3	170.4	-63.3	-157.5	167.1	0	0	110.7	G213	G213-E215 PolarHBondContact O-N 3.42Å
216	D	57.5	Low	61.2	Low	84 Å²	84	78.2 Å²	78.2	45%	0.449	41%	0.405	S	S	.	.			trans	-83	152.5	172	-62	-30.9	0	0	0	109.1	K214 S218 S219	K214-D216 PolarHBondContact O-N 3.4Å; D216-S218 PolarHBondContact O-N 2.94Å; D216-S219 WeakPolarHBondContact O-CB 3.37Å; D216-S219 PolarHBondContact O-N 3.48Å; D216-S219 PolarHBondContact O-OG 3.42Å
217	Q	58.1	Low	62.9	Low	180 Å²	180	79.4 Å²	79.4	84%	0.841	41%	0.407	S	S	*	.	H	α-helix	trans	-48.6	-32.6	176.1	-71.8	177.1	-3	0	0	113.1	S219 N220 E221	Q217-S219 VanDerWaalsContact C-N 3.3Å; Q217-S219 PolarHBondContact O-N 2.94Å; Q217-N220 PolarHBondContact O-N 3.23Å; Q217-E221 PolarHBondContact O-N 2.84Å
218	S	60.3	Low	64.5	Low	54 Å²	54	77.5 Å²	77.5	38%	0.378	40%	0.399	S	S	.	.	H	α-helix	trans	-65.2	-25.1	176.4	69.4	0	0	0	0	115	D216 F222	D216-S218 PolarHBondContact O-N 2.94Å; S218-F222 WeakPolarHBondContact O-CB 3.28Å; S218-F222 PolarHBondContact O-N 3.35Å
219	S	64.3	Low	66.3	Low	13 Å²	13	74.3 Å²	74.3	9%	0.091	38%	0.381	C	S	.	.	H	α-helix	trans	-75.6	-38.2	177.1	69.4	0	0	0	0	111.8	D216 Q217 F222 V223	D216-S219 WeakPolarHBondContact O-CB 3.37Å; D216-S219 PolarHBondContact O-N 3.48Å; D216-S219 PolarHBondContact O-OG 3.42Å; Q217-S219 VanDerWaalsContact C-N 3.3Å; Q217-S219 PolarHBondContact O-N 2.94Å; S219-F222 WeakPolarHBondContact O-CB 3.29Å; S219-F222 PolarHBondContact O-N 3.16Å; S219-V223 WeakPolarHBondContact O-CG2 3.23Å; S219-V223 PolarHBondContact O-N 3.47Å; S219-V223 VanDerWaalsContact O-N 3.12Å
220	N	69.6	Low	68.1	Low	106 Å²	106	68.4 Å²	68.4	57%	0.567	36%	0.356	S	S	*	.	H	α-helix	trans	-69.5	-44.3	175.7	-76.8	-25.8	0	0	0	111.9	Q217 F222 V223 E224	Q217-N220 PolarHBondContact O-N 3.23Å; N220-F222 PolarHBondContact O-N 2.89Å; N220-V223 PolarHBondContact O-N 3.04Å; N220-E224 WeakPolarHBondContact O-CB 3.46Å; N220-E224 PolarHBondContact O-N 2.88Å
221	E	71.4	Confident	69.9	Low	68 Å²	68	69 Å²	69	32%	0.318	36%	0.356	S	S	.	.	H	α-helix	trans	-56.8	-40.1	175	-175.9	176.5	-173.9	0	0	111.3	Q217 K225 K326 L377	Q217-E221 PolarHBondContact O-N 2.84Å; E221-K225 VanDerWaalsContact O-CB 3.27Å; E221-K225 WeakPolarHBondContact O-CB 3.28Å; E221-K225 PolarHBondContact O-N 3.37Å; E221-K326 IonicContact OE1-NZ 2.67Å; E221-K326 PolarHBondContact OE1-NZ 2.94Å; E221-K326 IonicContact OE2-NZ 3.36Å; E221-K326 PolarHBondContact OE2-NZ 2.98Å; E221-L377 WeakPolarHBondContact OE1-CD2 3.48Å
222	F	73.3	Confident	71.7	Confident	34 Å²	34	65.8 Å²	65.8	15%	0.149	34%	0.34	C	S	.	.	H	α-helix	trans	-65.7	-46.7	177.4	175.1	-105.1	0	0	0	113.6	S203 G206 V210 S218 S219 N220 E224 K225 R226	S203-F222 VanDerWaalsContact CB-CE2 3.46Å; S203-F222 WeakPolarHBondContact OG-CE2 3.44Å; G206-F222 VanDerWaalsContact C-CZ 3.48Å; G206-F222 VanDerWaalsContact CA-CZ 3.45Å; G206-F222 WeakPolarHBondContact O-CE1 3.37Å; V210-F222 HydrophobicContact CG2-CD1 3.71Å; V210-F222 HydrophobicContact CG2-CE1 4.19Å; S218-F222 WeakPolarHBondContact O-CB 3.28Å; S218-F222 PolarHBondContact O-N 3.35Å; S219-F222 WeakPolarHBondContact O-CB 3.29Å; S219-F222 PolarHBondContact O-N 3.16Å; N220-F222 PolarHBondContact O-N 2.89Å; F222-E224 VanDerWaalsContact C-N 3.31Å; F222-K225 PolarHBondContact O-N 3.48Å; F222-R226 VanDerWaalsContact CE1-NH1 3.33Å; F222-R226 WeakPolarHBondContact O-CB 3.47Å; F222-R226 PolarHBondContact O-N 2.8Å
223	V	77.5	Confident	73.6	Confident	18 Å²	18	60.6 Å²	60.6	11%	0.109	31%	0.309	C	S	.	.	H	α-helix	trans	-62.9	-42.1	179	171.9	0	0	0	0	110.1	P140 M151 V210 S219 N220 R226 R227	P140-V223 HydrophobicContact CB-CG1 3.39Å; P140-V223 HydrophobicContact CG-CG1 3.55Å; M151-V223 HydrophobicContact CE-CG2 4.35Å; V210-V223 HydrophobicContact CG2-CG2 4.03Å; S219-V223 WeakPolarHBondContact O-CG2 3.23Å; S219-V223 PolarHBondContact O-N 3.47Å; S219-V223 VanDerWaalsContact O-N 3.12Å; N220-V223 PolarHBondContact O-N 3.04Å; V223-R226 PolarHBondContact O-N 3.3Å; V223-R227 WeakPolarHBondContact O-CB 3.44Å; V223-R227 PolarHBondContact O-N 3.3Å
224	E	80.7	Confident	75.9	Confident	69 Å²	69	58 Å²	58	32%	0.322	28%	0.281	S	S	.	.	H	α-helix	trans	-67.9	-44.8	178.8	-177.2	50	-142.2	0	0	112.2	N220 F222 R226 R227 S228 Y378	N220-E224 WeakPolarHBondContact O-CB 3.46Å; N220-E224 PolarHBondContact O-N 2.88Å; F222-E224 VanDerWaalsContact C-N 3.31Å; E224-R226 PolarHBondContact O-N 2.97Å; E224-R227 VanDerWaalsContact CD-NE 3.28Å; E224-R227 PolarHBondContact O-N 2.98Å; E224-R227 IonicContact OE1-CZ 3.27Å; E224-R227 VanDerWaalsContact OE1-CZ 3.24Å; E224-R227 IonicContact OE1-NE 3.87Å; E224-R227 PolarHBondContact OE1-NE 3.33Å; E224-R227 IonicContact OE1-NH2 3.09Å; E224-R227 PolarHBondContact OE1-NH2 3.09Å; E224-R227 WeakPolarHBondContact OE2-CD 3.41Å; E224-R227 IonicContact OE2-NE 3.86Å; E224-R227 PolarHBondContact OE2-NE 3.04Å; E224-R227 VanDerWaalsContact OE2-NE 3.1Å; E224-S228 PolarHBondContact O-N 3.41Å; E224-S228 PolarHBondContact O-OG 3.41Å; E224-Y378 HydrophobicContact CG-CE1 4.39Å
225	K	79.8	Confident	78.2	Confident	77 Å²	77	52.6 Å²	52.6	34%	0.335	26%	0.259	S	S	.	.	H	α-helix	trans	-57.6	-38.7	173.4	178	165.2	172.4	140	0	111.9	E221 F222 S228 A229 E382	E221-K225 VanDerWaalsContact O-CB 3.27Å; E221-K225 WeakPolarHBondContact O-CB 3.28Å; E221-K225 PolarHBondContact O-N 3.37Å; F222-K225 PolarHBondContact O-N 3.48Å; K225-S228 PolarHBondContact O-OG 2.96Å; K225-A229 WeakPolarHBondContact O-CB 3.38Å; K225-A229 PolarHBondContact O-N 3.47Å; K225-A229 VanDerWaalsContact O-N 3.13Å; K225-E382 WeakPolarHBondContact CD-OE1 3.36Å; K225-E382 WeakPolarHBondContact CE-OE1 3.46Å; K225-E382 IonicContact NZ-OE1 3.15Å; K225-E382 PolarHBondContact NZ-OE1 3.47Å
226	R	83.9	Confident	80.1	Confident	24 Å²	24	45.5 Å²	45.5	9%	0.091	22%	0.224	C	C	.	.	H	α-helix	trans	-69	-46.4	175.5	176.2	170.3	-76.6	163	-4.1	112	Y153 F175 S203 M207 F222 V223 E224 S228 A229 L230	Y153-R226 WeakPolarHBondContact OH-CD 3.19Å; F175-R226 HydrophobicContact CD2-CG 4.3Å; S203-R226 PolarHBondContact O-NH2 2.85Å; M207-R226 VanDerWaalsContact CE-NH2 3.3Å; F222-R226 VanDerWaalsContact CE1-NH1 3.33Å; F222-R226 WeakPolarHBondContact O-CB 3.47Å; F222-R226 PolarHBondContact O-N 2.8Å; V223-R226 PolarHBondContact O-N 3.3Å; E224-R226 PolarHBondContact O-N 2.97Å; R226-S228 VanDerWaalsContact C-N 3.34Å; R226-S228 PolarHBondContact O-N 2.94Å; R226-A229 PolarHBondContact O-N 2.92Å; R226-L230 HydrophobicContact CG-CD1 3.98Å; R226-L230 HydrophobicContact CG-CG 4.39Å; R226-L230 VanDerWaalsContact O-CG 3.29Å; R226-L230 WeakPolarHBondContact O-CG 3.43Å; R226-L230 PolarHBondContact O-N 3.22Å
227	R	88.4	Confident	81.8	Confident	32 Å²	32	41.5 Å²	41.5	12%	0.121	20%	0.203	C	C	.	.	H	α-helix	trans	-57.5	-46.9	178.4	-178.9	-135.2	65.4	73.4	-3.9	110.9	V137 Y153 V223 E224 A229 L230 E231	V137-R227 HydrophobicContact CB-CG 4.2Å; V137-R227 HydrophobicContact CG1-CG 3.89Å; V137-R227 WeakPolarHBondContact O-CD 3.31Å; V137-R227 WeakPolarHBondContact O-CG 3.35Å; V137-R227 PolarHBondContact O-NH1 3.41Å; Y153-R227 HydrophobicContact CD1-CB 4.34Å; Y153-R227 HydrophobicContact CD1-CG 4.39Å; Y153-R227 HydrophobicContact CE1-CB 4.25Å; V223-R227 WeakPolarHBondContact O-CB 3.44Å; V223-R227 PolarHBondContact O-N 3.3Å; E224-R227 VanDerWaalsContact CD-NE 3.28Å; E224-R227 PolarHBondContact O-N 2.98Å; E224-R227 IonicContact OE1-CZ 3.27Å; E224-R227 VanDerWaalsContact OE1-CZ 3.24Å; E224-R227 IonicContact OE1-NE 3.87Å; E224-R227 PolarHBondContact OE1-NE 3.33Å; E224-R227 IonicContact OE1-NH2 3.09Å; E224-R227 PolarHBondContact OE1-NH2 3.09Å; E224-R227 WeakPolarHBondContact OE2-CD 3.41Å; E224-R227 IonicContact OE2-NE 3.86Å; E224-R227 PolarHBondContact OE2-NE 3.04Å; E224-R227 VanDerWaalsContact OE2-NE 3.1Å; R227-A229 PolarHBondContact O-N 3.15Å; R227-L230 PolarHBondContact O-N 3.33Å; R227-E231 VanDerWaalsContact NH1-CD 3.33Å; R227-E231 IonicContact NH1-OE1 3.75Å; R227-E231 IonicContact NH1-OE2 2.8Å; R227-E231 PolarHBondContact NH1-OE2 3.16Å; R227-E231 PolarHBondContact O-N 3.33Å
228	S	85.3	Confident	83.5	Confident	14 Å²	14	33 Å²	33	10%	0.098	16%	0.163	C	C	.	.	H	α-helix	trans	-64.5	-36.9	177.6	74	0	0	0	0	113	E224 K225 R226 R232	E224-S228 PolarHBondContact O-N 3.41Å; E224-S228 PolarHBondContact O-OG 3.41Å; K225-S228 PolarHBondContact O-OG 2.96Å; R226-S228 VanDerWaalsContact C-N 3.34Å; R226-S228 PolarHBondContact O-N 2.94Å; S228-R232 WeakPolarHBondContact O-CG 3.14Å; S228-R232 PolarHBondContact O-N 3.03Å; S228-R232 PolarHBondContact O-NE 2.81Å
229	A	87.1	Confident	85	Confident	15 Å²	15	35.3 Å²	35.3	12%	0.124	17%	0.167	C	C	.	.	H	α-helix	trans	-67	-39.3	174.5	0	0	0	0	0	112.3	P200 K225 R226 R227 Y233	P200-A229 HydrophobicContact CB-CB 3.96Å; P200-A229 HydrophobicContact CG-CB 4.12Å; K225-A229 WeakPolarHBondContact O-CB 3.38Å; K225-A229 PolarHBondContact O-N 3.47Å; K225-A229 VanDerWaalsContact O-N 3.13Å; R226-A229 PolarHBondContact O-N 2.92Å; R227-A229 PolarHBondContact O-N 3.15Å; A229-Y233 WeakPolarHBondContact O-CB 3.5Å; A229-Y233 PolarHBondContact O-N 2.96Å
230	L	91.4	Very high	86.3	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-65	-42.2	176	-69.2	167.1	0	0	0	111.7	V137 Y153 F175 F178 P200 R226 R227 Y233 L234	V137-L230 HydrophobicContact CG1-CB 4.45Å; Y153-L230 HydrophobicContact CD1-CD1 4.25Å; Y153-L230 HydrophobicContact CD2-CD1 3.79Å; Y153-L230 HydrophobicContact CE1-CD1 4.14Å; Y153-L230 HydrophobicContact CE2-CD1 3.71Å; Y153-L230 HydrophobicContact CG-CD1 4.09Å; F175-L230 HydrophobicContact CD2-CD1 4.3Å; F175-L230 HydrophobicContact CD2-CD2 3.84Å; F175-L230 HydrophobicContact CD2-CG 4.47Å; F175-L230 HydrophobicContact CE2-CD2 4.12Å; F178-L230 HydrophobicContact CB-CD2 3.92Å; F178-L230 HydrophobicContact CD1-CB 4.32Å; F178-L230 HydrophobicContact CD1-CD2 3.52Å; F178-L230 HydrophobicContact CD1-CG 4.46Å; F178-L230 HydrophobicContact CD2-CD2 3.77Å; F178-L230 HydrophobicContact CE1-CB 3.85Å; F178-L230 HydrophobicContact CE1-CD2 3.81Å; F178-L230 HydrophobicContact CE1-CG 4.3Å; F178-L230 HydrophobicContact CE2-CD1 4.24Å; F178-L230 HydrophobicContact CE2-CD2 4.08Å; F178-L230 HydrophobicContact CG-CD2 3.48Å; F178-L230 VanDerWaalsContact CG-CD2 3.48Å; F178-L230 HydrophobicContact CZ-CB 4.16Å; F178-L230 HydrophobicContact CZ-CD1 4.25Å; F178-L230 HydrophobicContact CZ-CD2 4.11Å; F178-L230 HydrophobicContact CZ-CG 4.41Å; P200-L230 HydrophobicContact CG-CD2 3.88Å; P200-L230 HydrophobicContact CG-CG 4.36Å; R226-L230 HydrophobicContact CG-CD1 3.98Å; R226-L230 HydrophobicContact CG-CG 4.39Å; R226-L230 VanDerWaalsContact O-CG 3.29Å; R226-L230 WeakPolarHBondContact O-CG 3.43Å; R226-L230 PolarHBondContact O-N 3.22Å; R227-L230 PolarHBondContact O-N 3.33Å; L230-Y233 PolarHBondContact O-N 2.98Å; L230-L234 PolarHBondContact O-N 3.34Å
231	E	92.2	Very high	87.3	Confident	50 Å²	50	31.7 Å²	31.7	23%	0.234	15%	0.148	C	C	.	.	H	α-helix	trans	-61	-49.5	175.4	-173.9	174.2	89.1	0	0	111.6	S136 V137 R227 Y233 L234 M235	S136-E231 VanDerWaalsContact CA-OE2 3.3Å; S136-E231 WeakPolarHBondContact CA-OE2 3.47Å; V137-E231 HydrophobicContact CB-CB 4Å; V137-E231 HydrophobicContact CG2-CB 3.8Å; V137-E231 HydrophobicContact CG2-CG 4.34Å; V137-E231 PolarHBondContact N-OE2 2.99Å; R227-E231 VanDerWaalsContact NH1-CD 3.33Å; R227-E231 IonicContact NH1-OE1 3.75Å; R227-E231 IonicContact NH1-OE2 2.8Å; R227-E231 PolarHBondContact NH1-OE2 3.16Å; R227-E231 PolarHBondContact O-N 3.33Å; E231-Y233 VanDerWaalsContact C-N 3.34Å; E231-Y233 PolarHBondContact O-N 3.3Å; E231-L234 PolarHBondContact O-N 3.12Å; E231-M235 HydrophobicContact CG-CG 4.41Å; E231-M235 WeakPolarHBondContact O-CB 3.45Å; E231-M235 WeakPolarHBondContact O-CG 3.47Å; E231-M235 PolarHBondContact O-N 3.04Å
232	R	89.9	Confident	88.4	Confident	48 Å²	48	31.4 Å²	31.4	18%	0.181	15%	0.149	C	C	.	.	H	α-helix	trans	-60.6	-42.6	177.1	-75.3	-176.4	-66.4	162.9	-11.1	112.5	S228 M235 R236 E382 D386	S228-R232 WeakPolarHBondContact O-CG 3.14Å; S228-R232 PolarHBondContact O-N 3.03Å; S228-R232 PolarHBondContact O-NE 2.81Å; R232-M235 PolarHBondContact O-N 2.65Å; R232-R236 WeakPolarHBondContact O-CG 3.5Å; R232-R236 PolarHBondContact O-N 2.92Å; R232-E382 IonicContact CZ-OE2 3.5Å; R232-E382 VanDerWaalsContact NH1-C 3.3Å; R232-E382 PolarHBondContact NH1-O 3.17Å; R232-E382 IonicContact NH1-OE2 3.04Å; R232-E382 IonicContact NH2-OE2 3.72Å; R232-E382 PolarHBondContact NH2-OE2 3.44Å; R232-D386 WeakPolarHBondContact CD-OD2 3.28Å; R232-D386 IonicContact CZ-OD2 2.86Å; R232-D386 IonicContact NE-OD2 2.68Å; R232-D386 VanDerWaalsContact NH1-CG 3.27Å; R232-D386 IonicContact NH1-OD2 3.98Å; R232-D386 PolarHBondContact NH1-OD2 3.5Å
233	Y	92.8	Very high	89.4	Confident	4 Å²	4	29.8 Å²	29.8	2%	0.016	14%	0.141	C	C	.	.	H	α-helix	trans	-55.9	-54.3	175.1	165.5	-104.3	0	0	0	110.9	F178 L181 H182 P197 P198 A229 L230 E231 M235 R236 T237	F178-Y233 HydrophobicContact CB-CE1 4.47Å; F178-Y233 HydrophobicContact CD1-CD1 4.09Å; F178-Y233 HydrophobicContact CD1-CE1 4.33Å; L181-Y233 HydrophobicContact CD2-CE1 4.39Å; H182-Y233 WeakPolarHBondContact CA-OH 3.33Å; H182-Y233 HydrophobicContact CB-CE2 4.4Å; H182-Y233 WeakPolarHBondContact CB-OH 3.4Å; H182-Y233 PolarHBondContact N-OH 3.37Å; P197-Y233 HydrophobicContact CB-CD2 4.14Å; P197-Y233 HydrophobicContact CB-CE2 4.3Å; P197-Y233 WeakPolarHBondContact O-CE2 3.43Å; P198-Y233 WeakPolarHBondContact O-CD2 3.49Å; A229-Y233 WeakPolarHBondContact O-CB 3.5Å; A229-Y233 PolarHBondContact O-N 2.96Å; L230-Y233 PolarHBondContact O-N 2.98Å; E231-Y233 VanDerWaalsContact C-N 3.34Å; E231-Y233 PolarHBondContact O-N 3.3Å; Y233-M235 PolarHBondContact O-N 3.01Å; Y233-R236 PolarHBondContact O-N 3.15Å; Y233-T237 PolarHBondContact O-N 3.27Å; Y233-T237 PolarHBondContact O-OG1 2.96Å; Y233-T237 VanDerWaalsContact O-OG1 3.07Å
234	L	94.3	Very high	90.2	Very high	2 Å²	2	29 Å²	29	1%	0.01	14%	0.136	C	C	.	.	H	α-helix	trans	-62.6	-45.5	179.8	-74.4	-178.6	0	0	0	112.3	I135 V137 V155 F178 L181 L230 E231 R236 T237 V238 F252	I135-L234 HydrophobicContact CD1-CB 4.01Å; I135-L234 HydrophobicContact CG2-CB 4.17Å; I135-L234 HydrophobicContact CG2-CD1 3.95Å; V137-L234 HydrophobicContact CG2-CD1 4.23Å; V155-L234 HydrophobicContact CG1-CD1 3.64Å; V155-L234 HydrophobicContact CG2-CD1 4.23Å; F178-L234 HydrophobicContact CD1-CD1 4.27Å; F178-L234 HydrophobicContact CD1-CD2 4.19Å; F178-L234 HydrophobicContact CD1-CG 4.07Å; F178-L234 HydrophobicContact CE1-CD1 3.48Å; F178-L234 VanDerWaalsContact CE1-CD1 3.48Å; F178-L234 HydrophobicContact CE1-CD2 4.22Å; F178-L234 HydrophobicContact CE1-CG 3.73Å; F178-L234 HydrophobicContact CZ-CD1 4.29Å; L181-L234 HydrophobicContact CD2-CD2 4.2Å; L230-L234 PolarHBondContact O-N 3.34Å; E231-L234 PolarHBondContact O-N 3.12Å; L234-R236 VanDerWaalsContact C-N 3.25Å; L234-R236 PolarHBondContact O-N 3.4Å; L234-T237 WeakPolarHBondContact O-CB 3.38Å; L234-T237 PolarHBondContact O-N 3.42Å; L234-V238 WeakPolarHBondContact O-CG2 3.4Å; L234-V238 PolarHBondContact O-N 3.16Å; L234-F252 HydrophobicContact CD1-CE1 3.97Å; L234-F252 HydrophobicContact CD2-CD1 4.06Å; L234-F252 HydrophobicContact CD2-CE1 3.63Å; L234-F252 HydrophobicContact CD2-CZ 4.41Å; L234-F252 HydrophobicContact CG-CE1 4.41Å
235	M	92.8	Very high	90.7	Very high	35 Å²	35	30.8 Å²	30.8	17%	0.172	14%	0.143	C	C	.	.	H	α-helix	trans	-56.3	-40.3	177.9	-80.2	-56.6	-57.7	0	0	111.8	I135 E231 R232 Y233 V238 K239	I135-M235 HydrophobicContact CB-CG 4.31Å; I135-M235 HydrophobicContact CB-SD 3.62Å; I135-M235 HydrophobicContact CG1-SD 4.2Å; I135-M235 PolarHBondContact N-SD 3.35Å; E231-M235 HydrophobicContact CG-CG 4.41Å; E231-M235 WeakPolarHBondContact O-CB 3.45Å; E231-M235 WeakPolarHBondContact O-CG 3.47Å; E231-M235 PolarHBondContact O-N 3.04Å; R232-M235 PolarHBondContact O-N 2.65Å; Y233-M235 PolarHBondContact O-N 3.01Å; M235-V238 WeakPolarHBondContact O-CG2 3.31Å; M235-V238 HydrophobicContact SD-CG2 4.37Å; M235-K239 WeakPolarHBondContact O-CB 3.42Å; M235-K239 VanDerWaalsContact O-CG 3.23Å; M235-K239 WeakPolarHBondContact O-CG 3.05Å; M235-K239 PolarHBondContact O-N 2.92Å
236	R	91.7	Very high	91.5	Very high	28 Å²	28	27.3 Å²	27.3	11%	0.106	13%	0.128	C	C	.	.	H	α-helix	trans	-71.3	-37.3	175	-70.7	-156	-171.9	97	-1.5	113.2	P197 R232 Y233 L234 V238 K239 H240 D386 L390	P197-R236 HydrophobicContact CB-CB 4.04Å; P197-R236 HydrophobicContact CG-CB 3.83Å; R232-R236 WeakPolarHBondContact O-CG 3.5Å; R232-R236 PolarHBondContact O-N 2.92Å; Y233-R236 PolarHBondContact O-N 3.15Å; L234-R236 VanDerWaalsContact C-N 3.25Å; L234-R236 PolarHBondContact O-N 3.4Å; R236-V238 VanDerWaalsContact C-N 3.34Å; R236-K239 PolarHBondContact O-N 3.07Å; R236-H240 PolarHBondContact O-N 2.69Å; R236-D386 IonicContact CZ-OD2 3.95Å; R236-D386 IonicContact NH1-OD1 3.7Å; R236-D386 PolarHBondContact NH1-OD1 2.94Å; R236-D386 VanDerWaalsContact NH1-OD1 3.14Å; R236-D386 IonicContact NH1-OD2 2.73Å; R236-D386 PolarHBondContact NH1-OD2 2.91Å; R236-D386 VanDerWaalsContact NH2-CG 3.33Å; R236-D386 IonicContact NH2-OD2 3.71Å; R236-D386 PolarHBondContact NH2-OD2 2.91Å; R236-L390 VanDerWaalsContact CZ-CD1 3.49Å
237	T	94.1	Very high	91.9	Very high	0 Å²	0	30.5 Å²	30.5	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-61.1	-44.7	175.4	-58.2	0	0	0	0	110.8	L185 Y233 L234 H240 L243 V249	L185-T237 HydrophobicContact CD1-CG2 3.77Å; Y233-T237 PolarHBondContact O-N 3.27Å; Y233-T237 PolarHBondContact O-OG1 2.96Å; Y233-T237 VanDerWaalsContact O-OG1 3.07Å; L234-T237 WeakPolarHBondContact O-CB 3.38Å; L234-T237 PolarHBondContact O-N 3.42Å; T237-H240 PolarHBondContact O-N 2.9Å; T237-L243 HydrophobicContact CG2-CB 4.07Å; T237-L243 HydrophobicContact CG2-CD1 4.49Å; T237-V249 HydrophobicContact CG2-CG1 4.35Å; T237-V249 HydrophobicContact CG2-CG2 3.75Å
238	V	92.9	Very high	92.2	Very high	2 Å²	2	30.1 Å²	30.1	1%	0.012	15%	0.153	C	C	.	.	H	α-helix	trans	-77.9	-24.1	-180	-60.6	0	0	0	0	114.2	V133 I135 L234 M235 R236 H240 L244 V249 L253	V133-V238 HydrophobicContact CB-CB 4.49Å; V133-V238 HydrophobicContact CB-CG2 4.3Å; V133-V238 HydrophobicContact CG1-CB 4.21Å; V133-V238 HydrophobicContact CG1-CG2 4.05Å; I135-V238 HydrophobicContact CD1-CB 4.24Å; I135-V238 HydrophobicContact CD1-CG1 3.49Å; I135-V238 VanDerWaalsContact CD1-CG1 3.49Å; I135-V238 HydrophobicContact CD1-CG2 3.76Å; I135-V238 HydrophobicContact CG1-CG2 4.35Å; L234-V238 WeakPolarHBondContact O-CG2 3.4Å; L234-V238 PolarHBondContact O-N 3.16Å; M235-V238 WeakPolarHBondContact O-CG2 3.31Å; M235-V238 HydrophobicContact SD-CG2 4.37Å; R236-V238 VanDerWaalsContact C-N 3.34Å; V238-H240 PolarHBondContact O-N 2.98Å; V238-L244 HydrophobicContact CB-CD1 3.85Å; V238-L244 HydrophobicContact CG1-CD1 3.9Å; V238-L244 WeakPolarHBondContact O-CD2 3.43Å; V238-V249 HydrophobicContact CG1-CG1 4.32Å; V238-L253 HydrophobicContact CG1-CD1 3.91Å
239	K	90.8	Very high	92.7	Very high	102 Å²	102	29.5 Å²	29.5	44%	0.443	15%	0.148	S	C	.	.	H	α-helix	trans	-68.3	-21.2	170.3	-80.4	178.4	176.4	-173.7	0	112.9	M235 R236 P241	M235-K239 WeakPolarHBondContact O-CB 3.42Å; M235-K239 VanDerWaalsContact O-CG 3.23Å; M235-K239 WeakPolarHBondContact O-CG 3.05Å; M235-K239 PolarHBondContact O-N 2.92Å; R236-K239 PolarHBondContact O-N 3.07Å; K239-P241 WeakPolarHBondContact O-CD 3.08Å
240	H	92.8	Very high	93	Very high	1 Å²	1	30.4 Å²	30.4	1%	0.005	15%	0.151	C	C	.	.	S	Bend	trans	-81.5	120.5	178.8	-172.1	-23.8	0	0	0	110.6	Y194 R236 T237 V238 I242 L243 L244 E469 R472	Y194-H240 AromaticContact CD1-CE1 3.74Å; Y194-H240 AromaticContact CD1-NE2 3.71Å; R236-H240 PolarHBondContact O-N 2.69Å; T237-H240 PolarHBondContact O-N 2.9Å; V238-H240 PolarHBondContact O-N 2.98Å; H240-I242 VanDerWaalsContact C-N 3.27Å; H240-I242 PolarHBondContact ND1-N 3.27Å; H240-I242 PolarHBondContact O-N 3.34Å; H240-I242 VanDerWaalsContact O-N 3.13Å; H240-L243 HydrophobicContact CB-CB 4.03Å; H240-L243 HydrophobicContact CB-CD1 3.93Å; H240-L243 HydrophobicContact CB-CG 3.96Å; H240-L243 VanDerWaalsContact CD2-CD1 3.44Å; H240-L243 WeakPolarHBondContact CD2-CD1 3.47Å; H240-L243 PolarHBondContact O-N 3.25Å; H240-L244 WeakPolarHBondContact O-CB 3.4Å; H240-L244 PolarHBondContact O-N 3.06Å; H240-E469 IonicContact CD2-OE2 2.81Å; H240-E469 IonicContact CE1-OE1 2.65Å; H240-E469 PolarHBondContact CE1-OE1 3.44Å; H240-E469 VanDerWaalsContact CE1-OE1 3.27Å; H240-E469 IonicContact CE1-OE2 3.62Å; H240-E469 IonicContact NE2-OE1 2.92Å; H240-E469 PolarHBondContact NE2-OE1 3.24Å; H240-E469 IonicContact NE2-OE2 2.66Å; H240-E469 PolarHBondContact NE2-OE2 3.39Å; H240-E469 VanDerWaalsContact NE2-OE2 3.09Å; H240-R472 PolarHBondContact CD2-NH1 3.15Å
241	P	91	Very high	93	Very high	42 Å²	42	34.1 Å²	34.1	27%	0.273	17%	0.168	S	C	.	.	H	α-helix	trans	-57.7	-34.2	-173.1	16	-31.2	0	0	0	115.1	F131 K239 K245	F131-P241 HydrophobicContact CE2-CB 3.66Å; F131-P241 HydrophobicContact CZ-CB 4.02Å; K239-P241 WeakPolarHBondContact O-CD 3.08Å; P241-K245 WeakPolarHBondContact O-CD 3.27Å; P241-K245 WeakPolarHBondContact O-CG 3.47Å
242	I	93.4	Very high	93.1	Very high	62 Å²	62	31.9 Å²	31.9	32%	0.318	16%	0.158	S	C	.	.	H	α-helix	trans	-83.9	-44.5	-178.7	-59.5	-59.4	0	0	0	110.9	Y189 Y194 H240 K245 D246	Y189-I242 HydrophobicContact CD1-CG2 4.18Å; Y189-I242 HydrophobicContact CE1-CG2 3.58Å; Y194-I242 HydrophobicContact CD1-CG1 4.5Å; Y194-I242 HydrophobicContact CE1-CB 4.2Å; Y194-I242 HydrophobicContact CE1-CG1 3.73Å; Y194-I242 HydrophobicContact CE1-CG2 4.3Å; Y194-I242 HydrophobicContact CE2-CG2 4.43Å; H240-I242 VanDerWaalsContact C-N 3.27Å; H240-I242 PolarHBondContact ND1-N 3.27Å; H240-I242 PolarHBondContact O-N 3.34Å; H240-I242 VanDerWaalsContact O-N 3.13Å; I242-K245 PolarHBondContact O-N 3.31Å; I242-D246 PolarHBondContact O-N 3.38Å
243	L	94.9	Very high	93.3	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-69	-36.8	-178.3	-55.4	179.8	0	0	0	111.9	L185 Y189 P197 T237 H240 K245 D246 V249	L185-L243 HydrophobicContact CD2-CD2 4.36Å; Y189-L243 HydrophobicContact CD1-CD2 4.37Å; Y189-L243 HydrophobicContact CD2-CD2 3.58Å; Y189-L243 HydrophobicContact CE2-CD2 3.91Å; Y189-L243 HydrophobicContact CG-CD2 3.84Å; P197-L243 HydrophobicContact CG-CD1 4.44Å; T237-L243 HydrophobicContact CG2-CB 4.07Å; T237-L243 HydrophobicContact CG2-CD1 4.49Å; H240-L243 HydrophobicContact CB-CB 4.03Å; H240-L243 HydrophobicContact CB-CD1 3.93Å; H240-L243 HydrophobicContact CB-CG 3.96Å; H240-L243 VanDerWaalsContact CD2-CD1 3.44Å; H240-L243 WeakPolarHBondContact CD2-CD1 3.47Å; H240-L243 PolarHBondContact O-N 3.25Å; L243-K245 PolarHBondContact O-N 2.97Å; L243-D246 VanDerWaalsContact O-CB 3.29Å; L243-D246 WeakPolarHBondContact O-CB 3.4Å; L243-D246 PolarHBondContact O-N 3.31Å; L243-V249 VanDerWaalsContact O-CG2 3.28Å; L243-V249 WeakPolarHBondContact O-CG2 3.37Å
244	L	93.3	Very high	93.1	Very high	1 Å²	1	31.7 Å²	31.7	1%	0.005	16%	0.159	C	C	.	.	H	α-helix	trans	-55.9	-38.7	175.2	175.2	58.2	0	0	0	112.6	F131 V133 M161 F164 V238 H240 D246 L250	F131-L244 HydrophobicContact CB-CD2 3.88Å; F131-L244 HydrophobicContact CD1-CD2 3.87Å; F131-L244 HydrophobicContact CG-CD2 3.83Å; V133-L244 HydrophobicContact CG2-CD1 4.37Å; V133-L244 HydrophobicContact CG2-CD2 4.2Å; M161-L244 HydrophobicContact CE-CD2 3.66Å; M161-L244 HydrophobicContact SD-CD2 3.73Å; F164-L244 HydrophobicContact CE2-CD1 4.31Å; F164-L244 HydrophobicContact CZ-CD1 3.95Å; V238-L244 HydrophobicContact CB-CD1 3.85Å; V238-L244 HydrophobicContact CG1-CD1 3.9Å; V238-L244 WeakPolarHBondContact O-CD2 3.43Å; H240-L244 WeakPolarHBondContact O-CB 3.4Å; H240-L244 PolarHBondContact O-N 3.06Å; L244-D246 VanDerWaalsContact C-N 3.26Å; L244-D246 PolarHBondContact O-N 3Å; L244-L250 WeakPolarHBondContact O-CD2 3.3Å
245	K	93.1	Very high	92.8	Very high	107 Å²	107	33.2 Å²	33.2	47%	0.465	17%	0.17	S	C	.	.	T	Hydrogen-bonded Turn	trans	-81.5	-4.1	-178.7	-63.6	176.6	-174.5	179.2	0	112.6	L163 P241 I242 L243	L163-K245 HydrophobicContact CD1-CG 4.31Å; P241-K245 WeakPolarHBondContact O-CD 3.27Å; P241-K245 WeakPolarHBondContact O-CG 3.47Å; I242-K245 PolarHBondContact O-N 3.31Å; L243-K245 PolarHBondContact O-N 2.97Å
246	D	95	Very high	92.1	Very high	4 Å²	4	37.6 Å²	37.6	2%	0.021	20%	0.199	C	C	.	.			trans	-67.8	132.7	178.6	-176.7	-91.6	0	0	0	110.6	L185 K188 Y189 I242 L243 L244 D248 V249 L250	L185-D246 HydrophobicContact CD2-CB 4Å; K188-D246 IonicContact NZ-OD1 2.68Å; K188-D246 PolarHBondContact NZ-OD1 3.41Å; K188-D246 IonicContact NZ-OD2 3.07Å; K188-D246 PolarHBondContact NZ-OD2 3.41Å; Y189-D246 HydrophobicContact CE2-CB 4.08Å; Y189-D246 WeakPolarHBondContact CE2-OD2 3.41Å; Y189-D246 WeakPolarHBondContact OH-CB 2.99Å; Y189-D246 PolarHBondContact OH-OD2 2.92Å; I242-D246 PolarHBondContact O-N 3.38Å; L243-D246 VanDerWaalsContact O-CB 3.29Å; L243-D246 WeakPolarHBondContact O-CB 3.4Å; L243-D246 PolarHBondContact O-N 3.31Å; L244-D246 VanDerWaalsContact C-N 3.26Å; L244-D246 PolarHBondContact O-N 3Å; D246-D248 VanDerWaalsContact C-N 3.26Å; D246-D248 PolarHBondContact O-N 3.41Å; D246-D248 WeakPolarHBondContact OD1-CA 3.49Å; D246-D248 WeakPolarHBondContact OD1-CB 3.43Å; D246-D248 PolarHBondContact OD1-N 3.13Å; D246-V249 HydrophobicContact CB-CG2 4.25Å; D246-V249 PolarHBondContact O-N 3.5Å; D246-L250 PolarHBondContact O-N 3.46Å; D246-L250 VanDerWaalsContact O-N 3.11Å
247	P	93.8	Very high	91.3	Very high	91 Å²	91	44.1 Å²	44.1	59%	0.591	23%	0.23	S	C	*	.	H	α-helix	trans	-57.2	-32.9	-180	-27.6	35.2	0	0	0	114.6	Q251	P247-Q251 WeakPolarHBondContact O-CB 3.35Å; P247-Q251 PolarHBondContact O-N 3.01Å
248	D	94.2	Very high	90.2	Very high	24 Å²	24	46.2 Å²	46.2	13%	0.128	24%	0.242	C	C	.	.	H	α-helix	trans	-70.8	-32.4	177.8	-67.8	-67	0	0	0	111.6	L181 K184 K188 D246 F252	L181-D248 HydrophobicContact CD1-CB 3.9Å; K184-D248 HydrophobicContact CD-CB 4.11Å; K184-D248 VanDerWaalsContact CD-OD1 3.22Å; K184-D248 WeakPolarHBondContact CD-OD1 3.42Å; K184-D248 WeakPolarHBondContact CD-OD2 3.44Å; K184-D248 IonicContact NZ-OD1 3.71Å; K184-D248 PolarHBondContact NZ-OD1 3.34Å; K188-D248 WeakPolarHBondContact CE-OD2 3.37Å; K188-D248 IonicContact NZ-OD2 3.94Å; K188-D248 PolarHBondContact NZ-OD2 3.15Å; D246-D248 VanDerWaalsContact C-N 3.26Å; D246-D248 PolarHBondContact O-N 3.41Å; D246-D248 WeakPolarHBondContact OD1-CA 3.49Å; D246-D248 WeakPolarHBondContact OD1-CB 3.43Å; D246-D248 PolarHBondContact OD1-N 3.13Å; D248-F252 WeakPolarHBondContact O-CB 3.38Å; D248-F252 PolarHBondContact O-N 3.09Å
249	V	94.6	Very high	89	Confident	2 Å²	2	50.9 Å²	50.9	1%	0.012	27%	0.272	C	S	.	.	H	α-helix	trans	-69	-48.9	174.8	174	0	0	0	0	110	L181 L185 T237 V238 L243 D246 Q251 F252 L253	L181-V249 HydrophobicContact CD1-CG2 3.9Å; L181-V249 HydrophobicContact CD2-CG2 4.43Å; L185-V249 HydrophobicContact CD1-CG2 3.87Å; L185-V249 HydrophobicContact CD2-CG2 3.99Å; L185-V249 HydrophobicContact CG-CG2 4.42Å; T237-V249 HydrophobicContact CG2-CG1 4.35Å; T237-V249 HydrophobicContact CG2-CG2 3.75Å; V238-V249 HydrophobicContact CG1-CG1 4.32Å; L243-V249 VanDerWaalsContact O-CG2 3.28Å; L243-V249 WeakPolarHBondContact O-CG2 3.37Å; D246-V249 HydrophobicContact CB-CG2 4.25Å; D246-V249 PolarHBondContact O-N 3.5Å; V249-Q251 VanDerWaalsContact C-N 3.33Å; V249-Q251 PolarHBondContact O-N 3.06Å; V249-F252 WeakPolarHBondContact O-CB 3.27Å; V249-F252 PolarHBondContact O-N 3.34Å; V249-F252 VanDerWaalsContact O-N 3.16Å; V249-L253 HydrophobicContact CG1-CD1 4.12Å; V249-L253 WeakPolarHBondContact O-CG 3.32Å; V249-L253 PolarHBondContact O-N 3.19Å
250	L	93.2	Very high	87.7	Confident	34 Å²	34	55.6 Å²	55.6	18%	0.178	29%	0.287	C	S	.	.	H	α-helix	trans	-60.1	-44.6	177.6	-61.9	178.3	0	0	0	111.2	F164 L244 D246 F252 L253 E254	F164-L250 HydrophobicContact CD1-CD2 4.4Å; F164-L250 HydrophobicContact CE1-CD2 3.64Å; F164-L250 HydrophobicContact CE2-CD2 4.48Å; F164-L250 HydrophobicContact CZ-CD2 3.7Å; L244-L250 WeakPolarHBondContact O-CD2 3.3Å; D246-L250 PolarHBondContact O-N 3.46Å; D246-L250 VanDerWaalsContact O-N 3.11Å; L250-F252 VanDerWaalsContact C-N 3.34Å; L250-F252 PolarHBondContact O-N 3Å; L250-L253 PolarHBondContact O-N 2.89Å; L250-E254 PolarHBondContact O-N 3.07Å
251	Q	92.9	Very high	86.2	Confident	77 Å²	77	56.6 Å²	56.6	36%	0.36	30%	0.295	S	S	.	.	H	α-helix	trans	-61.5	-43.4	175.3	-168.2	-177.9	27.2	0	0	111.4	P247 V249 L253 S255 L258	P247-Q251 WeakPolarHBondContact O-CB 3.35Å; P247-Q251 PolarHBondContact O-N 3.01Å; V249-Q251 VanDerWaalsContact C-N 3.33Å; V249-Q251 PolarHBondContact O-N 3.06Å; Q251-L253 VanDerWaalsContact C-N 3.25Å; Q251-L253 PolarHBondContact O-N 3.32Å; Q251-S255 WeakPolarHBondContact CG-OG 3.46Å; Q251-S255 WeakPolarHBondContact O-CB 3.45Å; Q251-S255 PolarHBondContact O-N 2.93Å; Q251-S255 PolarHBondContact O-OG 2.94Å; Q251-L258 HydrophobicContact CG-CD2 3.97Å
252	F	94	Very high	84.5	Confident	4 Å²	4	60.4 Å²	60.4	2%	0.018	32%	0.317	C	S	.	.	H	α-helix	trans	-62	-31.4	177.4	-178.9	-84.2	0	0	0	112.7	R173 D177 F178 L181 L234 D248 V249 L250 L258	R173-F252 HydrophobicContact CB-CE2 4.45Å; R173-F252 HydrophobicContact CB-CZ 3.99Å; R173-F252 HydrophobicContact CG-CE1 3.99Å; R173-F252 HydrophobicContact CG-CE2 4.02Å; R173-F252 HydrophobicContact CG-CZ 3.58Å; R173-F252 PolarHBondContact NE-O 3.17Å; R173-F252 PolarHBondContact NH2-O 2.89Å; D177-F252 HydrophobicContact CB-CE2 3.86Å; F178-F252 HydrophobicContact CD1-CE1 4.33Å; F178-F252 AromaticContact CD1-CZ 3.74Å; F178-F252 HydrophobicContact CD1-CZ 3.74Å; F178-F252 HydrophobicContact CD2-CE2 4.48Å; F178-F252 AromaticContact CD2-CZ 3.98Å; F178-F252 HydrophobicContact CD2-CZ 3.98Å; F178-F252 HydrophobicContact CE1-CE1 4.21Å; F178-F252 AromaticContact CE1-CZ 3.85Å; F178-F252 HydrophobicContact CE1-CZ 3.85Å; F178-F252 HydrophobicContact CE2-CZ 4.04Å; F178-F252 HydrophobicContact CG-CE2 4.37Å; F178-F252 AromaticContact CG-CZ 3.82Å; F178-F252 HydrophobicContact CG-CZ 3.82Å; F178-F252 AromaticContact CZ-CZ 3.98Å; F178-F252 HydrophobicContact CZ-CZ 3.98Å; L181-F252 HydrophobicContact CB-CD2 4.16Å; L181-F252 HydrophobicContact CD1-CB 4.28Å; L181-F252 HydrophobicContact CD2-CB 4.11Å; L181-F252 HydrophobicContact CD2-CD1 3.98Å; L181-F252 HydrophobicContact CD2-CD2 4.11Å; L181-F252 HydrophobicContact CD2-CE1 4.48Å; L181-F252 HydrophobicContact CD2-CG 3.79Å; L234-F252 HydrophobicContact CD1-CE1 3.97Å; L234-F252 HydrophobicContact CD2-CD1 4.06Å; L234-F252 HydrophobicContact CD2-CE1 3.63Å; L234-F252 HydrophobicContact CD2-CZ 4.41Å; L234-F252 HydrophobicContact CG-CE1 4.41Å; D248-F252 WeakPolarHBondContact O-CB 3.38Å; D248-F252 PolarHBondContact O-N 3.09Å; V249-F252 WeakPolarHBondContact O-CB 3.27Å; V249-F252 PolarHBondContact O-N 3.34Å; V249-F252 VanDerWaalsContact O-N 3.16Å; L250-F252 VanDerWaalsContact C-N 3.34Å; L250-F252 PolarHBondContact O-N 3Å; F252-L258 HydrophobicContact CD2-CD1 3.64Å; F252-L258 HydrophobicContact CE2-CD1 4.18Å; F252-L258 HydrophobicContact CG-CD1 4.38Å
253	L	93.2	Very high	82.5	Confident	0 Å²	0	63.9 Å²	63.9	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-83.3	-44.2	178.1	-63.8	173.4	0	0	0	112.1	I135 V155 F164 F169 V171 V238 V249 L250 Q251	I135-L253 HydrophobicContact CD1-CD1 4.24Å; I135-L253 HydrophobicContact CD1-CD2 3.73Å; V155-L253 HydrophobicContact CG1-CD2 4.24Å; F164-L253 HydrophobicContact CE1-CB 4.34Å; F164-L253 HydrophobicContact CE1-CD1 3.93Å; F164-L253 HydrophobicContact CZ-CD1 4.05Å; F169-L253 HydrophobicContact CE2-CB 4.03Å; F169-L253 WeakPolarHBondContact CE2-O 3.24Å; F169-L253 HydrophobicContact CZ-CB 4.34Å; V171-L253 WeakPolarHBondContact CG1-O 3.27Å; V171-L253 VanDerWaalsContact CG2-O 3.23Å; V171-L253 WeakPolarHBondContact CG2-O 3.5Å; V238-L253 HydrophobicContact CG1-CD1 3.91Å; V249-L253 HydrophobicContact CG1-CD1 4.12Å; V249-L253 WeakPolarHBondContact O-CG 3.32Å; V249-L253 PolarHBondContact O-N 3.19Å; L250-L253 PolarHBondContact O-N 2.89Å; Q251-L253 VanDerWaalsContact C-N 3.25Å; Q251-L253 PolarHBondContact O-N 3.32Å
254	E	89.7	Confident	80.7	Confident	47 Å²	47	64.9 Å²	64.9	22%	0.22	34%	0.343	C	S	.	.	H	α-helix	trans	-93	-26.7	-170.3	-66.1	-164.8	149	0	0	115.4	F164 K165 F169 L250	F164-E254 WeakPolarHBondContact CA-OE1 3.49Å; F164-E254 HydrophobicContact CD1-CG 3.97Å; K165-E254 PolarHBondContact N-OE1 3.04Å; K165-E254 IonicContact NZ-OE2 3.64Å; F169-E254 HydrophobicContact CE2-CG 4.06Å; F169-E254 HydrophobicContact CZ-CG 3.99Å; L250-E254 PolarHBondContact O-N 3.07Å
255	S	87.3	Confident	78.7	Confident	34 Å²	34	72 Å²	72	24%	0.238	38%	0.376	C	S	.	.			trans	-79.3	131.8	-167.3	-56.1	0	0	0	0	111.4	R173 Q251 E257	R173-S255 VanDerWaalsContact CZ-O 3.27Å; R173-S255 PolarHBondContact NH1-O 2.93Å; R173-S255 VanDerWaalsContact NH1-O 3.08Å; R173-S255 PolarHBondContact NH2-O 2.71Å; Q251-S255 WeakPolarHBondContact CG-OG 3.46Å; Q251-S255 WeakPolarHBondContact O-CB 3.45Å; Q251-S255 PolarHBondContact O-N 2.93Å; Q251-S255 PolarHBondContact O-OG 2.94Å; S255-E257 VanDerWaalsContact C-N 3.28Å; S255-E257 WeakPolarHBondContact CB-O 3.34Å; S255-E257 PolarHBondContact O-N 3.32Å
256	T	77.9	Confident	76.6	Confident	127 Å²	127	70.8 Å²	70.8	78%	0.779	39%	0.386	S	S	*	.	S	Bend	trans	-64.8	-36.6	175	45	0	0	0	0	111.6
257	E	74.6	Confident	74.5	Confident	165 Å²	165	74 Å²	74	77%	0.771	40%	0.403	S	S	*	.			trans	-118.9	136.7	179.2	-63.2	-176.2	179.4	0	0	111.6	S255	S255-E257 VanDerWaalsContact C-N 3.28Å; S255-E257 WeakPolarHBondContact CB-O 3.34Å; S255-E257 PolarHBondContact O-N 3.32Å
258	L	71.8	Confident	72.2	Confident	45 Å²	45	71.1 Å²	71.1	24%	0.236	39%	0.385	C	S	.	.			trans	-116.1	140.6	171.4	-71.2	177.1	0	0	0	110	R173 D177 Q251 F252 R260	R173-L258 VanDerWaalsContact CZ-CD1 3.44Å; R173-L258 VanDerWaalsContact NE-CD1 3.33Å; D177-L258 HydrophobicContact CB-CD1 4.26Å; Q251-L258 HydrophobicContact CG-CD2 3.97Å; F252-L258 HydrophobicContact CD2-CD1 3.64Å; F252-L258 HydrophobicContact CE2-CD1 4.18Å; F252-L258 HydrophobicContact CG-CD1 4.38Å; L258-R260 PolarHBondContact O-N 3.5Å
259	P	68.1	Low	69.6	Low	100 Å²	100	73.3 Å²	73.3	65%	0.649	40%	0.402	S	S	*	.			trans	-53.6	136.1	167.9	-22	31.6	0	0	0	110.2	A261	P259-A261 PolarHBondContact O-N 2.94Å
260	R	63.2	Low	67.2	Low	201 Å²	201	76.6 Å²	76.6	76%	0.758	43%	0.429	S	S	*	.			trans	-54.6	117.5	-178.2	-169.2	179	172.9	162.4	-1.7	109.4	L258 V262	L258-R260 PolarHBondContact O-N 3.5Å; R260-V262 PolarHBondContact O-N 2.85Å
261	A	61.8	Low	64.9	Low	21 Å²	21	77.3 Å²	77.3	17%	0.174	44%	0.444	C	S	.	.			trans	-55.8	113.8	179.7	0	0	0	0	0	111.4	P259 T264	P259-A261 PolarHBondContact O-N 2.94Å; A261-T264 HydrophobicContact CB-CG2 3.6Å
262	V	53.9	Low	62.6	Low	122 Å²	122	80 Å²	80	74%	0.739	46%	0.46	S	S	*	.	S	Bend	trans	-84.2	152.7	175.5	-67.8	0	0	0	0	110.3	R260 T264	R260-V262 PolarHBondContact O-N 2.85Å; V262-T264 VanDerWaalsContact C-N 3.27Å; V262-T264 PolarHBondContact O-N 3.07Å; V262-T264 VanDerWaalsContact O-N 3.16Å
263	N	52.5	Low	60.4	Low	136 Å²	136	85.7 Å²	85.7	73%	0.727	49%	0.49	S	S	*	.	S	Bend	trans	62	13.5	178	-67.3	-18.6	0	0	0	118.3	Q265 A266	N263-Q265 PolarHBondContact O-N 3.12Å; N263-A266 PolarHBondContact O-N 3.32Å; N263-A266 VanDerWaalsContact O-N 3.15Å
264	T	57.3	Low	58.4	Low	20 Å²	20	94.3 Å²	94.3	12%	0.123	52%	0.522	C	S	.	.	T	Hydrogen-bonded Turn	trans	-66.5	-6.8	173.4	60.3	0	0	0	0	114.3	S176 L179 K202 A261 V262 S268	S176-T264 WeakPolarHBondContact O-CG2 3.46Å; L179-T264 HydrophobicContact CB-CG2 4.24Å; K202-T264 PolarHBondContact NZ-O 3.48Å; A261-T264 HydrophobicContact CB-CG2 3.6Å; V262-T264 VanDerWaalsContact C-N 3.27Å; V262-T264 PolarHBondContact O-N 3.07Å; V262-T264 VanDerWaalsContact O-N 3.16Å; T264-S268 WeakPolarHBondContact O-CB 3.41Å; T264-S268 PolarHBondContact O-N 3.38Å
265	Q	49.7	Very low	56.4	Low	151 Å²	151	98.5 Å²	98.5	71%	0.706	54%	0.543	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.9	-36.3	171.6	-69	-89.3	-14.6	0	0	111.5	N263 L267 S268 S269	N263-Q265 PolarHBondContact O-N 3.12Å; Q265-L267 PolarHBondContact O-N 3.19Å; Q265-S268 WeakPolarHBondContact O-CA 3.49Å; Q265-S268 WeakPolarHBondContact O-CB 3.03Å; Q265-S268 PolarHBondContact O-N 3.23Å; Q265-S269 PolarHBondContact O-N 3.4Å; Q265-S269 PolarHBondContact O-OG 3.09Å
266	A	49.1	Very low	54.5	Low	81 Å²	81	101.5 Å²	101.5	67%	0.669	56%	0.56	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.5	-20.8	177.5	0	0	0	0	0	113.4	N263	N263-A266 PolarHBondContact O-N 3.32Å; N263-A266 VanDerWaalsContact O-N 3.15Å
267	L	50.8	Low	53.2	Low	73 Å²	73	100 Å²	100	38%	0.382	55%	0.548	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.3	-4.3	171	-60.4	174.1	0	0	0	112.3	L179 Q265	L179-L267 HydrophobicContact CB-CD1 4.08Å; L179-L267 WeakPolarHBondContact O-CD1 3.49Å; Q265-L267 PolarHBondContact O-N 3.19Å
268	S	46.5	Very low	52	Low	30 Å²	30	98.5 Å²	98.5	21%	0.21	54%	0.538	C	S	.	.	T	Hydrogen-bonded Turn	trans	-103.8	-29.4	-170.8	-157.9	0	0	0	0	114.7	K202 T264 Q265 A270	K202-S268 WeakPolarHBondContact CD-OG 3.32Å; K202-S268 WeakPolarHBondContact CE-OG 3.22Å; K202-S268 PolarHBondContact NZ-OG 2.81Å; T264-S268 WeakPolarHBondContact O-CB 3.41Å; T264-S268 PolarHBondContact O-N 3.38Å; Q265-S268 WeakPolarHBondContact O-CA 3.49Å; Q265-S268 WeakPolarHBondContact O-CB 3.03Å; Q265-S268 PolarHBondContact O-N 3.23Å; S268-A270 PolarHBondContact O-N 3.11Å
269	S	40	Very low	50.8	Low	70 Å²	70	99 Å²	99	49%	0.49	55%	0.549	S	S	.	.			trans	-82.4	109.1	-168.9	35.4	0	0	0	0	109.4	Q265	Q265-S269 PolarHBondContact O-N 3.4Å; Q265-S269 PolarHBondContact O-OG 3.09Å
270	A	42.6	Very low	50.1	Low	71 Å²	71	97.1 Å²	97.1	59%	0.587	54%	0.542	S	S	*	.			trans	-41.6	136.9	172.9	0	0	0	0	0	113.2	I204 S268 I272	I204-A270 HydrophobicContact CD1-CB 4.37Å; S268-A270 PolarHBondContact O-N 3.11Å; A270-I272 VanDerWaalsContact C-N 3.27Å; A270-I272 PolarHBondContact O-N 3.26Å
271	G	45.6	Very low	49.6	Very low	48 Å²	48	91.1 Å²	91.1	50%	0.495	53%	0.525	S	S	.	.	T	Hydrogen-bonded Turn	trans	62.1	-58.2	144.3	0	0	0	0	0	119.5	M275	G271-M275 WeakPolarHBondContact O-CG 3.45Å; G271-M275 PolarHBondContact O-N 3.22Å; G271-M275 VanDerWaalsContact O-N 3.13Å
272	I	43.9	Very low	49.1	Very low	133 Å²	133	92.5 Å²	92.5	68%	0.682	54%	0.537	S	S	*	.	H	α-helix	trans	-87.8	-47.6	-155.1	-58	174.3	0	0	0	111.9	A270 R274 M275 V276	A270-I272 VanDerWaalsContact C-N 3.27Å; A270-I272 PolarHBondContact O-N 3.26Å; I272-R274 PolarHBondContact O-N 2.92Å; I272-M275 WeakPolarHBondContact O-CB 3.4Å; I272-M275 PolarHBondContact O-N 3.48Å; I272-V276 WeakPolarHBondContact O-CG2 3.44Å; I272-V276 PolarHBondContact O-N 2.91Å
273	L	48.8	Very low	49	Very low	125 Å²	125	91.3 Å²	91.3	65%	0.654	53%	0.53	S	S	*	.	H	α-helix	trans	-67.3	-27.7	176.8	-135.4	93.4	0	0	0	112.2	N277	L273-N277 PolarHBondContact O-N 2.93Å; L273-N277 PolarHBondContact O-ND2 3.12Å
274	R	51.1	Low	48.9	Very low	180 Å²	180	89.3 Å²	89.3	68%	0.679	52%	0.519	S	S	*	.	H	α-helix	trans	-72.4	-32.4	173	-131.7	176.2	-174.3	176.2	2.1	111.2	I272 K278	I272-R274 PolarHBondContact O-N 2.92Å; R274-K278 WeakPolarHBondContact O-CB 3.34Å; R274-K278 WeakPolarHBondContact O-CG 3.29Å; R274-K278 PolarHBondContact O-N 3.34Å
275	M	48.2	Very low	48.6	Very low	135 Å²	135	93.9 Å²	93.9	67%	0.665	54%	0.537	S	S	*	.	H	α-helix	trans	-66.7	-39.5	175	-88.9	176.9	169	0	0	112.5	G271 I272 K278 A279	G271-M275 WeakPolarHBondContact O-CG 3.45Å; G271-M275 PolarHBondContact O-N 3.22Å; G271-M275 VanDerWaalsContact O-N 3.13Å; I272-M275 WeakPolarHBondContact O-CB 3.4Å; I272-M275 PolarHBondContact O-N 3.48Å; M275-K278 PolarHBondContact O-N 3.15Å; M275-A279 WeakPolarHBondContact O-CB 3.04Å; M275-A279 PolarHBondContact O-N 3.23Å
276	V	46.6	Very low	48.4	Very low	97 Å²	97	95 Å²	95	59%	0.588	54%	0.544	S	S	*	.	H	α-helix	trans	-69.9	-43	179.4	-163.8	0	0	0	0	111.4	I272 A279 A280	I272-V276 WeakPolarHBondContact O-CG2 3.44Å; I272-V276 PolarHBondContact O-N 2.91Å; V276-A279 PolarHBondContact O-N 3.4Å; V276-A280 PolarHBondContact O-N 3.49Å
277	N	50.3	Low	48.2	Very low	97 Å²	97	96.3 Å²	96.3	52%	0.519	54%	0.544	S	S	.	.	H	α-helix	trans	-67.9	-35.2	173	-73.6	-38.6	0	0	0	112.3	L273 D281	L273-N277 PolarHBondContact O-N 2.93Å; L273-N277 PolarHBondContact O-ND2 3.12Å; N277-D281 WeakPolarHBondContact O-CB 3.4Å; N277-D281 PolarHBondContact O-N 2.86Å
278	K	50.3	Low	48.1	Very low	132 Å²	132	95.2 Å²	95.2	57%	0.574	54%	0.538	S	S	*	.	H	α-helix	trans	-68.6	-33.4	173.5	-81.5	177.4	175.6	-170.8	0	112.8	R274 M275 A282	R274-K278 WeakPolarHBondContact O-CB 3.34Å; R274-K278 WeakPolarHBondContact O-CG 3.29Å; R274-K278 PolarHBondContact O-N 3.34Å; M275-K278 PolarHBondContact O-N 3.15Å; K278-A282 WeakPolarHBondContact O-CA 3.47Å; K278-A282 WeakPolarHBondContact O-CB 3.3Å; K278-A282 PolarHBondContact O-N 2.96Å
279	A	47.4	Very low	48.4	Very low	56 Å²	56	103 Å²	103	46%	0.463	57%	0.568	S	S	.	*	H	α-helix	trans	-71.5	-42.8	175.7	0	0	0	0	0	110.9	M275 V276 A282 V283	M275-A279 WeakPolarHBondContact O-CB 3.04Å; M275-A279 PolarHBondContact O-N 3.23Å; V276-A279 PolarHBondContact O-N 3.4Å; A279-A282 PolarHBondContact O-N 3.45Å; A279-V283 WeakPolarHBondContact O-CB 3.41Å; A279-V283 VanDerWaalsContact O-CG2 3.27Å; A279-V283 WeakPolarHBondContact O-CG2 3.42Å; A279-V283 PolarHBondContact O-N 3.43Å
280	A	51.8	Low	49.6	Very low	61 Å²	61	100.6 Å²	100.6	50%	0.504	55%	0.549	S	S	.	.	H	α-helix	trans	-62.7	-45.2	171.8	0	0	0	0	0	111.9	V276 A282 V283 N284	V276-A280 PolarHBondContact O-N 3.49Å; A280-A282 PolarHBondContact O-N 3.38Å; A280-V283 PolarHBondContact O-N 2.86Å; A280-N284 WeakPolarHBondContact O-CB 3.43Å; A280-N284 PolarHBondContact O-N 3.03Å
281	D	53.4	Low	50.6	Low	74 Å²	74	103.7 Å²	103.7	40%	0.396	56%	0.556	S	S	.	*	H	α-helix	trans	-66.1	-33.7	174.6	-83.1	-25.3	0	0	0	112.3	N277 N284 K285	N277-D281 WeakPolarHBondContact O-CB 3.4Å; N277-D281 PolarHBondContact O-N 2.86Å; D281-N284 PolarHBondContact O-N 2.87Å; D281-K285 VanDerWaalsContact O-CB 3.26Å; D281-K285 WeakPolarHBondContact O-CB 3.47Å; D281-K285 VanDerWaalsContact O-CG 3.29Å; D281-K285 WeakPolarHBondContact O-CG 3.43Å; D281-K285 PolarHBondContact O-N 3.32Å
282	A	51.5	Low	51.7	Low	51 Å²	51	103 Å²	103	42%	0.421	54%	0.54	S	S	.	.	H	α-helix	trans	-70.6	-39.1	176.6	0	0	0	0	0	111.9	K278 A279 A280 K285 M286	K278-A282 WeakPolarHBondContact O-CA 3.47Å; K278-A282 WeakPolarHBondContact O-CB 3.3Å; K278-A282 PolarHBondContact O-N 2.96Å; A279-A282 PolarHBondContact O-N 3.45Å; A280-A282 PolarHBondContact O-N 3.38Å; A282-K285 PolarHBondContact O-N 2.99Å; A282-M286 WeakPolarHBondContact O-CB 3.43Å; A282-M286 PolarHBondContact O-N 2.85Å
283	V	51.6	Low	53	Low	97 Å²	97	101.8 Å²	101.8	59%	0.588	54%	0.544	S	S	*	.	H	α-helix	trans	-67.5	-38	172.9	172.7	0	0	0	0	110.8	A279 A280 M286 T287	A279-V283 WeakPolarHBondContact O-CB 3.41Å; A279-V283 VanDerWaalsContact O-CG2 3.27Å; A279-V283 WeakPolarHBondContact O-CG2 3.42Å; A279-V283 PolarHBondContact O-N 3.43Å; A280-V283 PolarHBondContact O-N 2.86Å; V283-M286 PolarHBondContact O-N 3.41Å; V283-T287 PolarHBondContact O-N 2.82Å; V283-T287 PolarHBondContact O-OG1 3.02Å
284	N	50.1	Low	54.8	Low	94 Å²	94	97.7 Å²	97.7	50%	0.503	52%	0.522	S	S	.	.	H	α-helix	trans	-69	-38.8	174.7	-141.2	9.7	0	0	0	111.8	A280 D281 T287 I288	A280-N284 WeakPolarHBondContact O-CB 3.43Å; A280-N284 PolarHBondContact O-N 3.03Å; D281-N284 PolarHBondContact O-N 2.87Å; N284-T287 PolarHBondContact O-N 2.85Å; N284-I288 PolarHBondContact O-N 3.17Å
285	K	51	Low	56.6	Low	116 Å²	116	92.5 Å²	92.5	50%	0.504	52%	0.518	S	S	.	.	H	α-helix	trans	-66.1	-31.2	172.3	-81.9	-172.5	-176.5	-162.9	0	113.3	D281 A282 D399	D281-K285 VanDerWaalsContact O-CB 3.26Å; D281-K285 WeakPolarHBondContact O-CB 3.47Å; D281-K285 VanDerWaalsContact O-CG 3.29Å; D281-K285 WeakPolarHBondContact O-CG 3.43Å; D281-K285 PolarHBondContact O-N 3.32Å; A282-K285 PolarHBondContact O-N 2.99Å; K285-D399 WeakPolarHBondContact CE-OD1 3.42Å; K285-D399 IonicContact NZ-OD1 3.35Å; K285-D399 PolarHBondContact NZ-OD1 3.15Å; K285-D399 IonicContact NZ-OD2 2.69Å; K285-D399 PolarHBondContact NZ-OD2 3.2Å
286	M	45.1	Very low	58.9	Low	174 Å²	174	89.1 Å²	89.1	86%	0.857	50%	0.498	S	S	*	.	H	α-helix	trans	-76.9	-23.1	175.8	-105.5	174.8	173.9	0	0	113.4	A282 V283	A282-M286 WeakPolarHBondContact O-CB 3.43Å; A282-M286 PolarHBondContact O-N 2.85Å; V283-M286 PolarHBondContact O-N 3.41Å
287	T	45.6	Very low	61.2	Low	109 Å²	109	84.6 Å²	84.6	67%	0.669	47%	0.47	S	S	*	.	H	α-helix	trans	-94.7	-21	-176.3	-51.3	0	0	0	0	112.6	V283 N284	V283-T287 PolarHBondContact O-N 2.82Å; V283-T287 PolarHBondContact O-OG1 3.02Å; N284-T287 PolarHBondContact O-N 2.85Å
288	I	48.4	Very low	63.1	Low	49 Å²	49	85.6 Å²	85.6	25%	0.251	47%	0.472	S	S	.	.			trans	-116.7	91.8	-177.8	-58.5	178.4	0	0	0	109.2	N284 M290 M402 W405 Q406	N284-I288 PolarHBondContact O-N 3.17Å; I288-M290 PolarHBondContact O-N 3.01Å; I288-M402 HydrophobicContact CG2-CE 4.26Å; I288-M402 VanDerWaalsContact O-CE 3.27Å; I288-M402 WeakPolarHBondContact O-CE 3.46Å; I288-W405 HydrophobicContact CG2-CZ3 4.39Å; I288-Q406 HydrophobicContact CD1-CG 4.28Å
289	K	53.6	Low	65.2	Low	194 Å²	194	85.1 Å²	85.1	84%	0.843	47%	0.471	S	S	*	.			trans	-85.8	98.2	170.6	-158.7	179.4	-176.1	-173.4	0	107.9	N291	K289-N291 PolarHBondContact O-N 3.16Å; K289-N291 VanDerWaalsContact O-N 3.15Å
290	M	64.8	Low	67.5	Low	19 Å²	19	83.9 Å²	83.9	9%	0.094	46%	0.455	C	S	.	.			trans	-57.8	120	161.3	174.7	173.6	174.2	0	0	106.5	I288 E292 M402 W405 F459	I288-M290 PolarHBondContact O-N 3.01Å; M290-E292 PolarHBondContact O-N 2.78Å; M290-M402 HydrophobicContact CB-CE 3.33Å; M290-M402 HydrophobicContact CB-SD 3.24Å; M290-M402 WeakPolarHBondContact CB-SD 3.47Å; M290-M402 HydrophobicContact CG-SD 3.96Å; M290-M402 HydrophobicContact SD-SD 3.48Å; M290-W405 HydrophobicContact CB-CD2 4.21Å; M290-W405 HydrophobicContact CB-CE3 3.72Å; M290-W405 HydrophobicContact CB-CH2 3.88Å; M290-W405 HydrophobicContact CB-CZ2 4.32Å; M290-W405 HydrophobicContact CB-CZ3 3.55Å; M290-W405 HydrophobicContact CE-CB 4.25Å; M290-W405 HydrophobicContact CE-CD2 4.13Å; M290-W405 HydrophobicContact CE-CG 3.77Å; M290-W405 HydrophobicContact CG-CD2 3.65Å; M290-W405 HydrophobicContact CG-CE3 3.71Å; M290-W405 HydrophobicContact CG-CG 4.29Å; M290-W405 HydrophobicContact CG-CH2 3.98Å; M290-W405 HydrophobicContact CG-CZ2 3.89Å; M290-W405 HydrophobicContact CG-CZ3 3.88Å; M290-W405 HydrophobicContact SD-CB 3.97Å; M290-W405 HydrophobicContact SD-CD2 3.62Å; M290-W405 HydrophobicContact SD-CE3 3.88Å; M290-W405 HydrophobicContact SD-CG 3.67Å; M290-F459 HydrophobicContact CE-CE2 4.1Å; M290-F459 HydrophobicContact CE-CZ 3.79Å
291	N	63.7	Low	69.5	Low	136 Å²	136	84.9 Å²	84.9	73%	0.727	45%	0.45	S	S	*	.			trans	-73.2	90.6	166	-165.7	49.9	0	0	0	105.3	K289 S293	K289-N291 PolarHBondContact O-N 3.16Å; K289-N291 VanDerWaalsContact O-N 3.15Å; N291-S293 PolarHBondContact O-N 2.87Å
292	E	68.1	Low	71.4	Confident	33 Å²	33	88.4 Å²	88.4	15%	0.154	46%	0.464	C	S	.	.			trans	-58.2	107.9	176	-178.2	63.4	-103.3	0	0	107.4	M290 D294 F297 E298 R401	M290-E292 PolarHBondContact O-N 2.78Å; E292-D294 VanDerWaalsContact C-N 3.33Å; E292-D294 WeakPolarHBondContact CG-O 3.49Å; E292-D294 VanDerWaalsContact OE1-CB 3.3Å; E292-D294 WeakPolarHBondContact OE1-CB 3.44Å; E292-D294 PolarHBondContact OE1-N 3.32Å; E292-F297 HydrophobicContact CG-CB 4.17Å; E292-E298 HydrophobicContact CG-CB 4.09Å; E292-R401 IonicContact OE1-CZ 3.86Å; E292-R401 IonicContact OE1-NH1 3.34Å; E292-R401 PolarHBondContact OE1-NH1 3.44Å; E292-R401 IonicContact OE1-NH2 2.92Å; E292-R401 PolarHBondContact OE1-NH2 2.89Å; E292-R401 IonicContact OE2-CZ 2.63Å; E292-R401 IonicContact OE2-NH1 2.69Å; E292-R401 PolarHBondContact OE2-NH1 2.84Å; E292-R401 IonicContact OE2-NH2 3.57Å
293	S	70.8	Confident	73.5	Confident	109 Å²	109	89.3 Å²	89.3	76%	0.762	46%	0.459	S	S	*	.			trans	-86.1	-14.3	178	51.1	0	0	0	0	111.7	N291	N291-S293 PolarHBondContact O-N 2.87Å
294	D	86.8	Confident	75.6	Confident	39 Å²	39	84.7 Å²	84.7	21%	0.209	43%	0.431	C	S	.	.			trans	-96.3	101.7	-179.8	-168.7	-19.9	0	0	0	110.7	E292 W296 F297 E298 R467	E292-D294 VanDerWaalsContact C-N 3.33Å; E292-D294 WeakPolarHBondContact CG-O 3.49Å; E292-D294 VanDerWaalsContact OE1-CB 3.3Å; E292-D294 WeakPolarHBondContact OE1-CB 3.44Å; E292-D294 PolarHBondContact OE1-N 3.32Å; D294-W296 PolarHBondContact O-N 3.1Å; D294-W296 VanDerWaalsContact O-N 3.08Å; D294-W296 WeakPolarHBondContact OD1-CB 3.43Å; D294-W296 PolarHBondContact OD1-N 2.9Å; D294-W296 VanDerWaalsContact OD1-N 3.09Å; D294-F297 HydrophobicContact CB-CB 4.49Å; D294-F297 HydrophobicContact CB-CD2 3.91Å; D294-F297 PolarHBondContact O-N 3.01Å; D294-F297 WeakPolarHBondContact OD2-CD2 3.35Å; D294-F297 WeakPolarHBondContact OD2-CE2 3.23Å; D294-E298 PolarHBondContact O-N 3.31Å; D294-R467 VanDerWaalsContact CG-NH2 3.32Å; D294-R467 IonicContact OD1-NH2 3.88Å; D294-R467 PolarHBondContact OD1-NH2 3.08Å; D294-R467 IonicContact OD2-CZ 2.62Å; D294-R467 IonicContact OD2-NH2 2.65Å; D294-R467 PolarHBondContact OD2-NH2 3.42Å
295	A	90.6	Very high	77.8	Confident	70 Å²	70	84.2 Å²	84.2	58%	0.579	43%	0.426	S	S	*	.	H	α-helix	trans	-53.4	-30.8	179.3	0	0	0	0	0	113.2	E298 E299	A295-E298 PolarHBondContact O-N 3.45Å; A295-E299 WeakPolarHBondContact O-CB 3.37Å; A295-E299 PolarHBondContact O-N 3.43Å
296	W	94.9	Very high	80	Confident	65 Å²	65	82.3 Å²	82.3	25%	0.246	42%	0.421	C	S	.	.	H	α-helix	trans	-66.4	-41	178	-178	91.8	0	0	0	111.8	D294 K300 R467 V470	D294-W296 PolarHBondContact O-N 3.1Å; D294-W296 VanDerWaalsContact O-N 3.08Å; D294-W296 WeakPolarHBondContact OD1-CB 3.43Å; D294-W296 PolarHBondContact OD1-N 2.9Å; D294-W296 VanDerWaalsContact OD1-N 3.09Å; W296-K300 HydrophobicContact CD2-CG 3.95Å; W296-K300 HydrophobicContact CE3-CG 4.2Å; W296-K300 HydrophobicContact CH2-CB 4.48Å; W296-K300 HydrophobicContact CH2-CG 3.92Å; W296-K300 HydrophobicContact CZ2-CD 4.37Å; W296-K300 HydrophobicContact CZ2-CG 3.67Å; W296-K300 HydrophobicContact CZ3-CB 4.44Å; W296-K300 HydrophobicContact CZ3-CG 4.17Å; W296-K300 WeakPolarHBondContact O-CB 3.39Å; W296-K300 VanDerWaalsContact O-CG 3.31Å; W296-K300 WeakPolarHBondContact O-CG 3.25Å; W296-K300 PolarHBondContact O-N 2.88Å; W296-R467 HydrophobicContact CD2-CG 4.29Å; W296-R467 HydrophobicContact CE3-CG 3.93Å; W296-R467 HydrophobicContact CH2-CB 4.24Å; W296-R467 HydrophobicContact CH2-CG 3.73Å; W296-R467 HydrophobicContact CZ2-CB 4.46Å; W296-R467 HydrophobicContact CZ2-CG 4.05Å; W296-R467 HydrophobicContact CZ3-CG 3.66Å; W296-V470 HydrophobicContact CH2-CB 3.98Å; W296-V470 HydrophobicContact CH2-CG1 4.04Å; W296-V470 HydrophobicContact CH2-CG2 4.16Å; W296-V470 HydrophobicContact CZ2-CB 4.37Å; W296-V470 HydrophobicContact CZ2-CG1 4.1Å
297	F	94.6	Very high	82.4	Confident	2 Å²	2	75.2 Å²	75.2	1%	0.009	39%	0.387	C	S	.	.	H	α-helix	trans	-71.3	-38.9	178.5	-82.6	-81.1	0	0	0	111.4	E292 D294 K300 Q301 F398 I466 R467	E292-F297 HydrophobicContact CG-CB 4.17Å; D294-F297 HydrophobicContact CB-CB 4.49Å; D294-F297 HydrophobicContact CB-CD2 3.91Å; D294-F297 PolarHBondContact O-N 3.01Å; D294-F297 WeakPolarHBondContact OD2-CD2 3.35Å; D294-F297 WeakPolarHBondContact OD2-CE2 3.23Å; F297-K300 PolarHBondContact O-N 3.41Å; F297-Q301 WeakPolarHBondContact O-CB 3.47Å; F297-Q301 PolarHBondContact O-N 3.01Å; F297-F398 HydrophobicContact CD1-CD1 4.01Å; F297-F398 AromaticContact CD1-CE1 3.89Å; F297-F398 HydrophobicContact CD1-CE1 3.89Å; F297-F398 HydrophobicContact CE1-CD1 4.14Å; F297-F398 HydrophobicContact CE1-CE1 4Å; F297-I466 HydrophobicContact CE1-CB 4.19Å; F297-I466 HydrophobicContact CE1-CG2 3.75Å; F297-I466 HydrophobicContact CZ-CB 4.42Å; F297-I466 HydrophobicContact CZ-CG2 4.38Å; F297-R467 HydrophobicContact CZ-CG 4.29Å
298	E	91.1	Very high	84.8	Confident	118 Å²	118	70.6 Å²	70.6	55%	0.551	36%	0.358	S	S	*	.	H	α-helix	trans	-59.3	-50.7	174.8	-174.9	174	-156.4	0	0	111	E292 D294 A295 Q301 Q302	E292-E298 HydrophobicContact CG-CB 4.09Å; D294-E298 PolarHBondContact O-N 3.31Å; A295-E298 PolarHBondContact O-N 3.45Å; E298-Q301 PolarHBondContact O-N 3.22Å; E298-Q302 PolarHBondContact O-N 2.91Å
299	E	94.3	Very high	87.1	Confident	121 Å²	121	72.6 Å²	72.6	57%	0.565	37%	0.369	S	S	*	.	H	α-helix	trans	-59.4	-50.6	177.4	-172.9	-163.1	152.9	0	0	111.4	A295 Q301 Q302 H303	A295-E299 WeakPolarHBondContact O-CB 3.37Å; A295-E299 PolarHBondContact O-N 3.43Å; E299-Q301 PolarHBondContact O-N 2.82Å; E299-Q302 PolarHBondContact O-N 2.82Å; E299-H303 WeakPolarHBondContact O-CB 3.39Å; E299-H303 PolarHBondContact O-N 3.34Å
300	K	95.3	Very high	89.2	Confident	30 Å²	30	68.3 Å²	68.3	13%	0.13	35%	0.351	C	S	.	.	H	α-helix	trans	-65.4	-38.3	-178.6	-73.9	-58.9	-168.7	179.5	0	112.2	W296 F297 H303 F304 F398 V470 E474	W296-K300 HydrophobicContact CD2-CG 3.95Å; W296-K300 HydrophobicContact CE3-CG 4.2Å; W296-K300 HydrophobicContact CH2-CB 4.48Å; W296-K300 HydrophobicContact CH2-CG 3.92Å; W296-K300 HydrophobicContact CZ2-CD 4.37Å; W296-K300 HydrophobicContact CZ2-CG 3.67Å; W296-K300 HydrophobicContact CZ3-CB 4.44Å; W296-K300 HydrophobicContact CZ3-CG 4.17Å; W296-K300 WeakPolarHBondContact O-CB 3.39Å; W296-K300 VanDerWaalsContact O-CG 3.31Å; W296-K300 WeakPolarHBondContact O-CG 3.25Å; W296-K300 PolarHBondContact O-N 2.88Å; F297-K300 PolarHBondContact O-N 3.41Å; K300-H303 PolarHBondContact O-N 3.15Å; K300-F304 WeakPolarHBondContact O-CD2 3.43Å; K300-F304 PolarHBondContact O-N 3.04Å; K300-F398 HydrophobicContact CB-CZ 4.14Å; K300-V470 HydrophobicContact CD-CG1 4.34Å; K300-E474 IonicContact NZ-OE1 3.92Å; K300-E474 PolarHBondContact NZ-OE1 2.9Å; K300-E474 IonicContact NZ-OE2 2.99Å; K300-E474 PolarHBondContact NZ-OE2 3.27Å
301	Q	93.4	Very high	90.7	Very high	83 Å²	83	68 Å²	68	39%	0.388	35%	0.351	S	S	.	.	H	α-helix	trans	-63	-46.3	176.4	-174.1	168.9	-8.3	0	0	110.7	F297 E298 E299 H303 F304 E305	F297-Q301 WeakPolarHBondContact O-CB 3.47Å; F297-Q301 PolarHBondContact O-N 3.01Å; E298-Q301 PolarHBondContact O-N 3.22Å; E299-Q301 PolarHBondContact O-N 2.82Å; Q301-H303 VanDerWaalsContact C-N 3.34Å; Q301-H303 PolarHBondContact O-N 3.19Å; Q301-F304 PolarHBondContact O-N 3.04Å; Q301-E305 WeakPolarHBondContact O-CG 3.32Å; Q301-E305 PolarHBondContact O-N 2.74Å
302	Q	93.8	Very high	92.2	Very high	147 Å²	147	66.3 Å²	66.3	69%	0.687	34%	0.337	S	S	*	.	H	α-helix	trans	-62.1	-41.9	175	-170.7	178.8	17.3	0	0	112	E298 E299 F304 E305 N306	E298-Q302 PolarHBondContact O-N 2.91Å; E299-Q302 PolarHBondContact O-N 2.82Å; Q302-F304 PolarHBondContact O-N 3.06Å; Q302-E305 PolarHBondContact O-N 2.87Å; Q302-N306 PolarHBondContact O-N 3.49Å
303	H	95.9	Very high	93.6	Very high	71 Å²	71	71 Å²	71	33%	0.329	36%	0.357	S	S	.	.	H	α-helix	trans	-57.7	-50.1	176.5	179.2	69.9	0	0	0	111.7	E299 K300 Q301 N306 L307 E474	E299-H303 WeakPolarHBondContact O-CB 3.39Å; E299-H303 PolarHBondContact O-N 3.34Å; K300-H303 PolarHBondContact O-N 3.15Å; Q301-H303 VanDerWaalsContact C-N 3.34Å; Q301-H303 PolarHBondContact O-N 3.19Å; H303-N306 PolarHBondContact O-N 2.82Å; H303-L307 VanDerWaalsContact O-CB 3.29Å; H303-L307 WeakPolarHBondContact O-CB 3.29Å; H303-L307 PolarHBondContact O-N 2.83Å; H303-E474 IonicContact CD2-OE1 2.67Å
304	F	96.5	Very high	94.8	Very high	0 Å²	0	69.3 Å²	69.3	0%	0	34%	0.338	C	S	.	.	H	α-helix	trans	-69.4	-32	-179.9	-79.8	-67.6	0	0	0	113.2	K300 Q301 Q302 L307 D308 I391 V394 F398 V470 F473 E474	K300-F304 WeakPolarHBondContact O-CD2 3.43Å; K300-F304 PolarHBondContact O-N 3.04Å; Q301-F304 PolarHBondContact O-N 3.04Å; Q302-F304 PolarHBondContact O-N 3.06Å; F304-L307 HydrophobicContact CD1-CD2 4.21Å; F304-L307 HydrophobicContact CE1-CD2 4.36Å; F304-D308 VanDerWaalsContact O-CB 3.26Å; F304-D308 WeakPolarHBondContact O-CB 3.37Å; F304-D308 PolarHBondContact O-N 3.39Å; F304-I391 HydrophobicContact CB-CG2 4.38Å; F304-I391 HydrophobicContact CD1-CG1 4.27Å; F304-I391 HydrophobicContact CD1-CG2 4.09Å; F304-V394 HydrophobicContact CD1-CG1 4.13Å; F304-V394 HydrophobicContact CD2-CG1 3.8Å; F304-V394 HydrophobicContact CE1-CG1 4.08Å; F304-V394 HydrophobicContact CE1-CG2 4.38Å; F304-V394 HydrophobicContact CE2-CG1 3.76Å; F304-V394 HydrophobicContact CG-CG1 4.01Å; F304-V394 HydrophobicContact CZ-CG1 3.9Å; F304-F398 AromaticContact CD2-CE2 3.77Å; F304-F398 HydrophobicContact CD2-CE2 3.77Å; F304-F398 HydrophobicContact CD2-CZ 4.03Å; F304-F398 HydrophobicContact CE2-CE2 4.47Å; F304-F398 HydrophobicContact CE2-CZ 4.32Å; F304-F398 HydrophobicContact CG-CE2 4.49Å; F304-V470 HydrophobicContact CE2-CG1 3.79Å; F304-V470 HydrophobicContact CE2-CG2 4.32Å; F304-V470 HydrophobicContact CZ-CG1 4.08Å; F304-F473 AromaticContact CE1-CD1 3.95Å; F304-F473 HydrophobicContact CE1-CD1 3.95Å; F304-F473 AromaticContact CE1-CE1 3.76Å; F304-F473 HydrophobicContact CE1-CE1 3.76Å; F304-F473 HydrophobicContact CZ-CD1 4.06Å; F304-F473 HydrophobicContact CZ-CE1 4.34Å; F304-E474 HydrophobicContact CZ-CG 4.25Å
305	E	95.4	Very high	95.3	Very high	84 Å²	84	69 Å²	69	39%	0.393	34%	0.335	S	S	.	.	H	α-helix	trans	-63.3	-47.4	171.7	-74.6	-66.9	170.1	0	0	111.7	Q301 Q302 D308 L309 K395	Q301-E305 WeakPolarHBondContact O-CG 3.32Å; Q301-E305 PolarHBondContact O-N 2.74Å; Q302-E305 PolarHBondContact O-N 2.87Å; E305-D308 PolarHBondContact O-N 3.41Å; E305-L309 PolarHBondContact O-N 3.12Å; E305-L309 VanDerWaalsContact O-N 3.14Å; E305-K395 WeakPolarHBondContact OE1-CE 3.04Å; E305-K395 IonicContact OE1-NZ 3.27Å; E305-K395 PolarHBondContact OE1-NZ 3.38Å; E305-K395 IonicContact OE2-NZ 2.72Å; E305-K395 PolarHBondContact OE2-NZ 2.98Å
306	N	97.1	Very high	95.4	Very high	75 Å²	75	68.1 Å²	68.1	40%	0.401	33%	0.329	S	S	.	.	H	α-helix	trans	-65.2	-42.4	177.3	179.3	57.4	0	0	0	111.5	Q302 H303 D308 L309 Q310	Q302-N306 PolarHBondContact O-N 3.49Å; H303-N306 PolarHBondContact O-N 2.82Å; N306-D308 PolarHBondContact O-N 3.15Å; N306-L309 PolarHBondContact O-N 2.91Å; N306-Q310 PolarHBondContact ND2-NE2 3Å; N306-Q310 WeakPolarHBondContact O-CG 3.48Å; N306-Q310 PolarHBondContact O-N 3.27Å; N306-Q310 PolarHBondContact OD1-NE2 3.29Å
307	L	96.5	Very high	95.6	Very high	25 Å²	25	68.8 Å²	68.8	13%	0.131	34%	0.343	C	S	.	.	H	α-helix	trans	-63.2	-41.3	178	-174.8	69	0	0	0	112.2	H303 F304 L309 Q310 L311 I391	H303-L307 VanDerWaalsContact O-CB 3.29Å; H303-L307 WeakPolarHBondContact O-CB 3.29Å; H303-L307 PolarHBondContact O-N 2.83Å; F304-L307 HydrophobicContact CD1-CD2 4.21Å; F304-L307 HydrophobicContact CE1-CD2 4.36Å; L307-L309 VanDerWaalsContact C-N 3.34Å; L307-L309 PolarHBondContact O-N 3.45Å; L307-Q310 PolarHBondContact O-N 3.25Å; L307-L311 HydrophobicContact CD1-CD1 3.96Å; L307-L311 HydrophobicContact CD1-CG 4.16Å; L307-L311 HydrophobicContact CD2-CD1 4.38Å; L307-L311 HydrophobicContact CG-CD1 3.83Å; L307-L311 HydrophobicContact CG-CG 4.37Å; L307-L311 WeakPolarHBondContact O-CB 3.3Å; L307-L311 WeakPolarHBondContact O-CG 3.35Å; L307-L311 PolarHBondContact O-N 2.96Å; L307-I391 HydrophobicContact CB-CD1 4.48Å; L307-I391 HydrophobicContact CD2-CD1 3.55Å; L307-I391 HydrophobicContact CD2-CG1 4.2Å; L307-I391 HydrophobicContact CG-CD1 3.71Å
308	D	95.3	Very high	95.6	Very high	12 Å²	12	69 Å²	69	6%	0.064	35%	0.345	C	S	.	.	H	α-helix	trans	-58.4	-46.6	174.9	-174.6	36.3	0	0	0	110.9	F304 E305 N306 K312 I391 K395	F304-D308 VanDerWaalsContact O-CB 3.26Å; F304-D308 WeakPolarHBondContact O-CB 3.37Å; F304-D308 PolarHBondContact O-N 3.39Å; E305-D308 PolarHBondContact O-N 3.41Å; N306-D308 PolarHBondContact O-N 3.15Å; D308-K312 WeakPolarHBondContact O-CB 3.34Å; D308-K312 WeakPolarHBondContact O-CD 3.5Å; D308-K312 VanDerWaalsContact O-CG 3.25Å; D308-K312 WeakPolarHBondContact O-CG 3.42Å; D308-K312 PolarHBondContact O-N 3.13Å; D308-K312 WeakPolarHBondContact OD1-CE 3.39Å; D308-K312 IonicContact OD1-NZ 3.11Å; D308-K312 PolarHBondContact OD1-NZ 3.33Å; D308-K312 IonicContact OD2-NZ 3.16Å; D308-K312 PolarHBondContact OD2-NZ 2.87Å; D308-I391 HydrophobicContact CB-CG2 3.79Å; D308-K395 IonicContact OD2-NZ 3.64Å; D308-K395 PolarHBondContact OD2-NZ 3.06Å
309	L	96.2	Very high	95.7	Very high	91 Å²	91	67.2 Å²	67.2	48%	0.476	34%	0.336	S	S	.	.	H	α-helix	trans	-61.9	-47.6	177.8	179.9	63.5	0	0	0	112	E305 N306 L307 K313	E305-L309 PolarHBondContact O-N 3.12Å; E305-L309 VanDerWaalsContact O-N 3.14Å; N306-L309 PolarHBondContact O-N 2.91Å; L307-L309 VanDerWaalsContact C-N 3.34Å; L307-L309 PolarHBondContact O-N 3.45Å; L309-K313 WeakPolarHBondContact O-CG 2.97Å; L309-K313 PolarHBondContact O-N 2.8Å
310	Q	97.4	Very high	95.7	Very high	104 Å²	104	63.8 Å²	63.8	49%	0.486	33%	0.326	S	S	.	.	H	α-helix	trans	-66.7	-45.3	-178	-70.2	-178.8	0.6	0	0	111.7	N306 L307 K312 K313 L314	N306-Q310 PolarHBondContact ND2-NE2 3Å; N306-Q310 WeakPolarHBondContact O-CG 3.48Å; N306-Q310 PolarHBondContact O-N 3.27Å; N306-Q310 PolarHBondContact OD1-NE2 3.29Å; L307-Q310 PolarHBondContact O-N 3.25Å; Q310-K312 PolarHBondContact O-N 3.1Å; Q310-K313 PolarHBondContact O-N 2.84Å; Q310-L314 PolarHBondContact O-N 3.49Å
311	L	96.3	Very high	95.7	Very high	14 Å²	14	65.1 Å²	65.1	7%	0.073	33%	0.334	C	S	.	.	H	α-helix	trans	-67.6	-34.4	179.6	-77.4	173.9	0	0	0	112.6	L307 L314 H315 L384 V388 I391 F481	L307-L311 HydrophobicContact CD1-CD1 3.96Å; L307-L311 HydrophobicContact CD1-CG 4.16Å; L307-L311 HydrophobicContact CD2-CD1 4.38Å; L307-L311 HydrophobicContact CG-CD1 3.83Å; L307-L311 HydrophobicContact CG-CG 4.37Å; L307-L311 WeakPolarHBondContact O-CB 3.3Å; L307-L311 WeakPolarHBondContact O-CG 3.35Å; L307-L311 PolarHBondContact O-N 2.96Å; L311-L314 HydrophobicContact CD2-CD2 4.49Å; L311-L314 PolarHBondContact O-N 3.47Å; L311-H315 VanDerWaalsContact O-CB 3.24Å; L311-H315 WeakPolarHBondContact O-CB 3.35Å; L311-H315 PolarHBondContact O-N 3.03Å; L311-L384 HydrophobicContact CD2-CD2 3.61Å; L311-V388 HydrophobicContact CB-CG2 3.81Å; L311-I391 HydrophobicContact CD1-CD1 3.33Å; L311-F481 HydrophobicContact CD2-CE1 4.37Å; L311-F481 HydrophobicContact CD2-CZ 3.99Å
312	K	95.6	Very high	95.7	Very high	100 Å²	100	61.6 Å²	61.6	44%	0.435	32%	0.318	S	S	.	.	H	α-helix	trans	-62.4	-44.3	172.4	-79.4	169.7	175.7	159.4	0	112.2	D308 Q310 H315 A316 V388	D308-K312 WeakPolarHBondContact O-CB 3.34Å; D308-K312 WeakPolarHBondContact O-CD 3.5Å; D308-K312 VanDerWaalsContact O-CG 3.25Å; D308-K312 WeakPolarHBondContact O-CG 3.42Å; D308-K312 PolarHBondContact O-N 3.13Å; D308-K312 WeakPolarHBondContact OD1-CE 3.39Å; D308-K312 IonicContact OD1-NZ 3.11Å; D308-K312 PolarHBondContact OD1-NZ 3.33Å; D308-K312 IonicContact OD2-NZ 3.16Å; D308-K312 PolarHBondContact OD2-NZ 2.87Å; Q310-K312 PolarHBondContact O-N 3.1Å; K312-H315 PolarHBondContact O-N 3.42Å; K312-A316 WeakPolarHBondContact O-CB 3.48Å; K312-A316 PolarHBondContact O-N 3.17Å; K312-V388 HydrophobicContact CD-CG1 4.34Å; K312-V388 HydrophobicContact CG-CG1 3.68Å; K312-V388 HydrophobicContact CG-CG2 3.98Å
313	K	97.4	Very high	95.7	Very high	132 Å²	132	57.8 Å²	57.8	57%	0.574	31%	0.307	S	S	*	.	H	α-helix	trans	-63	-44.1	176.3	-72.2	177.7	179.4	-177.1	0	111.5	L309 Q310 A316 S317	L309-K313 WeakPolarHBondContact O-CG 2.97Å; L309-K313 PolarHBondContact O-N 2.8Å; Q310-K313 PolarHBondContact O-N 2.84Å; K313-A316 PolarHBondContact O-N 2.79Å; K313-S317 PolarHBondContact O-N 2.99Å; K313-S317 PolarHBondContact O-OG 3.5Å
314	L	97.3	Very high	95.6	Very high	72 Å²	72	59.5 Å²	59.5	38%	0.377	32%	0.315	S	S	.	.	H	α-helix	trans	-63.6	-45.7	176.7	-178.9	58.3	0	0	0	111.3	Q310 L311 A316 S317 V318 F380 L384	Q310-L314 PolarHBondContact O-N 3.49Å; L311-L314 HydrophobicContact CD2-CD2 4.49Å; L311-L314 PolarHBondContact O-N 3.47Å; L314-A316 PolarHBondContact O-N 2.83Å; L314-S317 WeakPolarHBondContact O-CB 3.37Å; L314-S317 PolarHBondContact O-N 3.28Å; L314-V318 HydrophobicContact CD1-CG2 4.17Å; L314-V318 WeakPolarHBondContact O-CG2 3.49Å; L314-V318 PolarHBondContact O-N 3.21Å; L314-F380 HydrophobicContact CD2-CZ 4.43Å; L314-L384 HydrophobicContact CD2-CD1 4.19Å; L314-L384 HydrophobicContact CD2-CD2 3.63Å; L314-L384 HydrophobicContact CG-CD1 3.82Å; L314-L384 HydrophobicContact CG-CD2 4.05Å
315	H	95.4	Very high	95.6	Very high	32 Å²	32	61.8 Å²	61.8	15%	0.148	32%	0.323	C	S	.	.	H	α-helix	trans	-55.9	-50.6	176.3	-177.8	-107.8	0	0	0	111.7	L311 K312 S317 V318 E319 S381 L384 G385	L311-H315 VanDerWaalsContact O-CB 3.24Å; L311-H315 WeakPolarHBondContact O-CB 3.35Å; L311-H315 PolarHBondContact O-N 3.03Å; K312-H315 PolarHBondContact O-N 3.42Å; H315-S317 VanDerWaalsContact C-N 3.29Å; H315-S317 PolarHBondContact O-N 3.43Å; H315-V318 PolarHBondContact O-N 3.48Å; H315-V318 VanDerWaalsContact O-N 3.16Å; H315-E319 IonicContact CE1-OE1 2.69Å; H315-E319 PolarHBondContact CE1-OE1 3.42Å; H315-E319 VanDerWaalsContact CE1-OE1 3.27Å; H315-E319 IonicContact CE1-OE2 3.97Å; H315-E319 PolarHBondContact CE1-OE2 3.03Å; H315-E319 IonicContact ND1-OE2 2.74Å; H315-E319 PolarHBondContact ND1-OE2 2.95Å; H315-E319 VanDerWaalsContact ND1-OE2 3.11Å; H315-E319 IonicContact NE2-OE1 3.37Å; H315-E319 WeakPolarHBondContact O-CG 3.5Å; H315-E319 PolarHBondContact O-N 3.11Å; H315-S381 PolarHBondContact CD2-O 3.26Å; H315-S381 PolarHBondContact NE2-O 2.75Å; H315-L384 HydrophobicContact CB-CB 4.09Å; H315-G385 VanDerWaalsContact CD2-CA 3.45Å; H315-G385 WeakPolarHBondContact CD2-CA 3.34Å; H315-G385 PolarHBondContact CD2-N 3.48Å; H315-G385 WeakPolarHBondContact NE2-CA 3.34Å
316	A	94.5	Very high	95.4	Very high	53 Å²	53	61 Å²	61	44%	0.438	32%	0.319	S	S	.	.	H	α-helix	trans	-60.6	-38.5	178.2	0	0	0	0	0	112.5	K312 K313 L314 E319 S320	K312-A316 WeakPolarHBondContact O-CB 3.48Å; K312-A316 PolarHBondContact O-N 3.17Å; K313-A316 PolarHBondContact O-N 2.79Å; L314-A316 PolarHBondContact O-N 2.83Å; A316-E319 PolarHBondContact O-N 3.13Å; A316-S320 PolarHBondContact O-N 2.95Å
317	S	97.4	Very high	95.4	Very high	78 Å²	78	62.7 Å²	62.7	55%	0.545	32%	0.324	S	S	.	.	H	α-helix	trans	-65.9	-40.3	176.8	-54.6	0	0	0	0	111.7	K313 L314 H315 S320 L321	K313-S317 PolarHBondContact O-N 2.99Å; K313-S317 PolarHBondContact O-OG 3.5Å; L314-S317 WeakPolarHBondContact O-CB 3.37Å; L314-S317 PolarHBondContact O-N 3.28Å; H315-S317 VanDerWaalsContact C-N 3.29Å; H315-S317 PolarHBondContact O-N 3.43Å; S317-S320 PolarHBondContact O-N 3.16Å; S317-L321 PolarHBondContact O-N 2.91Å
318	V	96	Very high	95.4	Very high	7 Å²	7	65.2 Å²	65.2	4%	0.042	34%	0.337	C	S	.	.	H	α-helix	trans	-72	-35.7	176.9	177.7	0	0	0	0	111.3	L314 H315 S320 L321 V322 F380 L384	L314-V318 HydrophobicContact CD1-CG2 4.17Å; L314-V318 WeakPolarHBondContact O-CG2 3.49Å; L314-V318 PolarHBondContact O-N 3.21Å; H315-V318 PolarHBondContact O-N 3.48Å; H315-V318 VanDerWaalsContact O-N 3.16Å; V318-S320 VanDerWaalsContact C-N 3.32Å; V318-S320 PolarHBondContact O-N 2.99Å; V318-L321 WeakPolarHBondContact O-CB 3.18Å; V318-L321 PolarHBondContact O-N 3.15Å; V318-V322 WeakPolarHBondContact O-CG2 3.29Å; V318-V322 PolarHBondContact O-N 3.45Å; V318-F380 HydrophobicContact CG1-CB 4.36Å; V318-F380 HydrophobicContact CG1-CD1 3.86Å; V318-F380 HydrophobicContact CG1-CG 4.29Å; V318-F380 HydrophobicContact CG2-CD1 3.76Å; V318-F380 HydrophobicContact CG2-CE1 3.6Å; V318-F380 HydrophobicContact CG2-CZ 4.31Å; V318-L384 HydrophobicContact CB-CD1 4.12Å; V318-L384 HydrophobicContact CG2-CD1 3.73Å
319	E	92	Very high	95.4	Very high	80 Å²	80	65 Å²	65	37%	0.374	34%	0.337	S	S	.	.	H	α-helix	trans	-60.8	-42.5	171.8	-75.4	-177	123.6	0	0	111.4	H315 A316 V322 C323	H315-E319 IonicContact CE1-OE1 2.69Å; H315-E319 PolarHBondContact CE1-OE1 3.42Å; H315-E319 VanDerWaalsContact CE1-OE1 3.27Å; H315-E319 IonicContact CE1-OE2 3.97Å; H315-E319 PolarHBondContact CE1-OE2 3.03Å; H315-E319 IonicContact ND1-OE2 2.74Å; H315-E319 PolarHBondContact ND1-OE2 2.95Å; H315-E319 VanDerWaalsContact ND1-OE2 3.11Å; H315-E319 IonicContact NE2-OE1 3.37Å; H315-E319 WeakPolarHBondContact O-CG 3.5Å; H315-E319 PolarHBondContact O-N 3.11Å; A316-E319 PolarHBondContact O-N 3.13Å; E319-V322 WeakPolarHBondContact O-CB 3.06Å; E319-V322 PolarHBondContact O-N 2.79Å; E319-C323 PolarHBondContact O-N 3.49Å; E319-C323 VanDerWaalsContact O-N 3.14Å; E319-C323 PolarHBondContact O-SG 3.2Å
320	S	94.6	Very high	95.4	Very high	50 Å²	50	64.3 Å²	64.3	35%	0.35	34%	0.336	S	S	.	.	H	α-helix	trans	-62.8	-40.6	172.8	174.9	0	0	0	0	112.2	A316 S317 V318 V322 C323 H324	A316-S320 PolarHBondContact O-N 2.95Å; S317-S320 PolarHBondContact O-N 3.16Å; V318-S320 VanDerWaalsContact C-N 3.32Å; V318-S320 PolarHBondContact O-N 2.99Å; S320-V322 VanDerWaalsContact C-N 3.33Å; S320-V322 PolarHBondContact O-N 3.38Å; S320-C323 WeakPolarHBondContact O-CB 3.47Å; S320-C323 PolarHBondContact O-N 3.37Å; S320-H324 PolarHBondContact O-N 3.46Å; S320-H324 PolarHBondContact O-ND1 3.16Å; S320-H324 PolarHBondContact OG-CE1 3.33Å
321	L	95.6	Very high	95.5	Very high	58 Å²	58	63.7 Å²	63.7	30%	0.304	34%	0.337	S	S	.	.	H	α-helix	trans	-58.4	-43.9	174.7	179.5	64.3	0	0	0	111.9	S317 V318 C323 H324 R325	S317-L321 PolarHBondContact O-N 2.91Å; V318-L321 WeakPolarHBondContact O-CB 3.18Å; V318-L321 PolarHBondContact O-N 3.15Å; L321-C323 VanDerWaalsContact C-N 3.34Å; L321-C323 PolarHBondContact O-N 2.9Å; L321-H324 PolarHBondContact O-N 3.4Å; L321-R325 WeakPolarHBondContact O-CB 3.37Å; L321-R325 PolarHBondContact O-N 3.24Å
322	V	94	Very high	95.5	Very high	8 Å²	8	63.7 Å²	63.7	5%	0.048	34%	0.337	C	S	.	.	H	α-helix	trans	-58.3	-46.7	175.5	173.1	0	0	0	0	110.6	V318 E319 S320 R325 K326 D376 L377	V318-V322 WeakPolarHBondContact O-CG2 3.29Å; V318-V322 PolarHBondContact O-N 3.45Å; E319-V322 WeakPolarHBondContact O-CB 3.06Å; E319-V322 PolarHBondContact O-N 2.79Å; S320-V322 VanDerWaalsContact C-N 3.33Å; S320-V322 PolarHBondContact O-N 3.38Å; V322-R325 PolarHBondContact O-N 2.96Å; V322-K326 HydrophobicContact CG1-CD 4.43Å; V322-K326 WeakPolarHBondContact O-CG 3.38Å; V322-K326 PolarHBondContact O-N 3.4Å; V322-D376 HydrophobicContact CG2-CB 3.61Å; V322-L377 HydrophobicContact CG1-CB 4.06Å; V322-L377 HydrophobicContact CG1-CD1 4.48Å; V322-L377 HydrophobicContact CG2-CB 4.03Å
323	C	92.3	Very high	95.6	Very high	68 Å²	68	59.8 Å²	59.8	46%	0.459	32%	0.323	S	S	.	.	H	α-helix	trans	-59.9	-51.5	178.2	-67.1	0	0	0	0	111.6	E319 S320 L321 R325 K326 E327	E319-C323 PolarHBondContact O-N 3.49Å; E319-C323 VanDerWaalsContact O-N 3.14Å; E319-C323 PolarHBondContact O-SG 3.2Å; S320-C323 WeakPolarHBondContact O-CB 3.47Å; S320-C323 PolarHBondContact O-N 3.37Å; L321-C323 VanDerWaalsContact C-N 3.34Å; L321-C323 PolarHBondContact O-N 2.9Å; C323-R325 VanDerWaalsContact C-N 3.27Å; C323-R325 PolarHBondContact O-N 3.3Å; C323-K326 PolarHBondContact O-N 2.83Å; C323-K326 VanDerWaalsContact O-N 3.16Å; C323-E327 WeakPolarHBondContact O-CG 3.15Å; C323-E327 PolarHBondContact O-N 2.96Å
324	H	95.8	Very high	95.7	Very high	107 Å²	107	58.6 Å²	58.6	50%	0.495	32%	0.32	S	S	.	.	H	α-helix	trans	-60.9	-35.5	179.1	-63	149.8	0	0	0	112.4	S320 L321 E327 L328	S320-H324 PolarHBondContact O-N 3.46Å; S320-H324 PolarHBondContact O-ND1 3.16Å; S320-H324 PolarHBondContact OG-CE1 3.33Å; L321-H324 PolarHBondContact O-N 3.4Å; H324-E327 IonicContact CD2-OE2 3.83Å; H324-E327 PolarHBondContact O-N 3.45Å; H324-L328 WeakPolarHBondContact O-CB 3.47Å; H324-L328 PolarHBondContact O-N 3.34Å
325	R	94.8	Very high	95.7	Very high	47 Å²	47	59.9 Å²	59.9	18%	0.177	32%	0.323	C	S	.	.	H	α-helix	trans	-67.4	-40.6	176.9	-156.8	89.2	69	-177.7	4.7	112	L321 V322 C323 L328 S329 H369 Q372 A373 D376	L321-R325 WeakPolarHBondContact O-CB 3.37Å; L321-R325 PolarHBondContact O-N 3.24Å; V322-R325 PolarHBondContact O-N 2.96Å; C323-R325 VanDerWaalsContact C-N 3.27Å; C323-R325 PolarHBondContact O-N 3.3Å; R325-L328 PolarHBondContact O-N 3.12Å; R325-S329 PolarHBondContact O-N 3.21Å; R325-H369 WeakPolarHBondContact CG-O 3.37Å; R325-Q372 HydrophobicContact CG-CB 4.39Å; R325-A373 HydrophobicContact CB-CB 3.81Å; R325-A373 HydrophobicContact CG-CB 3.82Å; R325-D376 IonicContact CZ-OD2 3.23Å; R325-D376 VanDerWaalsContact CZ-OD2 3.23Å; R325-D376 IonicContact NE-OD2 3.9Å; R325-D376 PolarHBondContact NE-OD2 2.81Å; R325-D376 IonicContact NH2-OD1 2.81Å; R325-D376 PolarHBondContact NH2-OD1 3.38Å; R325-D376 IonicContact NH2-OD2 2.78Å; R325-D376 PolarHBondContact NH2-OD2 3.47Å
326	K	92.9	Very high	95.8	Very high	69 Å²	69	58.4 Å²	58.4	30%	0.3	32%	0.316	S	S	.	.	H	α-helix	trans	-64.2	-42.7	173.8	-71.4	-176.4	177.4	-174.3	0	111.2	E221 V322 C323 S329 V330 A373	E221-K326 IonicContact OE1-NZ 2.67Å; E221-K326 PolarHBondContact OE1-NZ 2.94Å; E221-K326 IonicContact OE2-NZ 3.36Å; E221-K326 PolarHBondContact OE2-NZ 2.98Å; V322-K326 HydrophobicContact CG1-CD 4.43Å; V322-K326 WeakPolarHBondContact O-CG 3.38Å; V322-K326 PolarHBondContact O-N 3.4Å; C323-K326 PolarHBondContact O-N 2.83Å; C323-K326 VanDerWaalsContact O-N 3.16Å; K326-S329 WeakPolarHBondContact O-CB 3.34Å; K326-S329 PolarHBondContact O-N 3.13Å; K326-V330 WeakPolarHBondContact O-CG2 3.05Å; K326-V330 PolarHBondContact O-N 3.45Å; K326-A373 HydrophobicContact CG-CB 3.87Å
327	E	95.3	Very high	96	Very high	109 Å²	109	62 Å²	62	51%	0.509	32%	0.321	S	S	.	.	H	α-helix	trans	-63	-42.1	175.4	-72.3	170.2	-170.5	0	0	112	C323 H324 S329 V330 N331	C323-E327 WeakPolarHBondContact O-CG 3.15Å; C323-E327 PolarHBondContact O-N 2.96Å; H324-E327 IonicContact CD2-OE2 3.83Å; H324-E327 PolarHBondContact O-N 3.45Å; E327-S329 VanDerWaalsContact C-N 3.35Å; E327-S329 PolarHBondContact O-N 3.42Å; E327-V330 PolarHBondContact O-N 2.67Å; E327-N331 VanDerWaalsContact O-CG 3.3Å; E327-N331 PolarHBondContact O-N 3.2Å; E327-N331 PolarHBondContact O-ND2 3.43Å
328	L	96.8	Very high	96	Very high	78 Å²	78	61.6 Å²	61.6	41%	0.408	32%	0.319	S	S	.	.	H	α-helix	trans	-59.8	-45.2	175.4	-178.4	62.2	0	0	0	111.5	H324 R325 V330 N331 T332	H324-L328 WeakPolarHBondContact O-CB 3.47Å; H324-L328 PolarHBondContact O-N 3.34Å; R325-L328 PolarHBondContact O-N 3.12Å; L328-V330 PolarHBondContact O-N 3.34Å; L328-N331 PolarHBondContact O-N 3.24Å; L328-T332 WeakPolarHBondContact O-CB 3.45Å; L328-T332 PolarHBondContact O-N 2.84Å; L328-T332 PolarHBondContact O-OG1 2.97Å
329	S	96.7	Very high	96.1	Very high	8 Å²	8	61.6 Å²	61.6	6%	0.056	32%	0.32	C	S	.	.	H	α-helix	trans	-54.2	-52	172.6	151.9	0	0	0	0	111.7	R325 K326 E327 N331 T332 A333 D366 Q370	R325-S329 PolarHBondContact O-N 3.21Å; K326-S329 WeakPolarHBondContact O-CB 3.34Å; K326-S329 PolarHBondContact O-N 3.13Å; E327-S329 VanDerWaalsContact C-N 3.35Å; E327-S329 PolarHBondContact O-N 3.42Å; S329-N331 VanDerWaalsContact C-N 3.32Å; S329-N331 PolarHBondContact O-N 3.49Å; S329-T332 PolarHBondContact O-N 3.31Å; S329-A333 PolarHBondContact O-N 3.17Å; S329-D366 WeakPolarHBondContact CA-OD1 3.48Å; S329-D366 VanDerWaalsContact CB-OD1 3.28Å; S329-D366 WeakPolarHBondContact CB-OD1 3.29Å; S329-D366 VanDerWaalsContact O-OD1 3.04Å; S329-D366 PolarHBondContact OG-OD1 3.2Å; S329-Q370 WeakPolarHBondContact OG-CG 3.36Å; S329-Q370 PolarHBondContact OG-NE2 3.37Å
330	V	96.2	Very high	96.3	Very high	76 Å²	76	59.2 Å²	59.2	46%	0.461	31%	0.314	S	S	.	.	H	α-helix	trans	-58.2	-44.3	179.6	171.8	0	0	0	0	111.7	K326 E327 L328 A333 Q334	K326-V330 WeakPolarHBondContact O-CG2 3.05Å; K326-V330 PolarHBondContact O-N 3.45Å; E327-V330 PolarHBondContact O-N 2.67Å; L328-V330 PolarHBondContact O-N 3.34Å; V330-A333 PolarHBondContact O-N 3.44Å; V330-Q334 WeakPolarHBondContact O-CG 3.32Å; V330-Q334 PolarHBondContact O-N 3.28Å
331	N	97.8	Very high	96.4	Very high	92 Å²	92	63.3 Å²	63.3	49%	0.492	33%	0.329	S	S	.	.	H	α-helix	trans	-67	-41.3	179.3	-68.5	-22	0	0	0	111.8	E327 L328 S329 A333 Q334 F335	E327-N331 VanDerWaalsContact O-CG 3.3Å; E327-N331 PolarHBondContact O-N 3.2Å; E327-N331 PolarHBondContact O-ND2 3.43Å; L328-N331 PolarHBondContact O-N 3.24Å; S329-N331 VanDerWaalsContact C-N 3.32Å; S329-N331 PolarHBondContact O-N 3.49Å; N331-A333 VanDerWaalsContact C-N 3.34Å; N331-A333 PolarHBondContact O-N 2.91Å; N331-Q334 PolarHBondContact O-N 2.99Å; N331-F335 PolarHBondContact O-N 2.66Å
332	T	98.2	Very high	96.4	Very high	13 Å²	13	65 Å²	65	8%	0.08	34%	0.338	C	S	.	.	H	α-helix	trans	-60.3	-43.7	174.2	-64.4	0	0	0	0	111.3	L328 S329 Q334 F335 A336 E362 I365 D366 H369	L328-T332 WeakPolarHBondContact O-CB 3.45Å; L328-T332 PolarHBondContact O-N 2.84Å; L328-T332 PolarHBondContact O-OG1 2.97Å; S329-T332 PolarHBondContact O-N 3.31Å; T332-Q334 VanDerWaalsContact C-N 3.32Å; T332-Q334 PolarHBondContact O-N 2.9Å; T332-F335 PolarHBondContact O-N 3.48Å; T332-A336 PolarHBondContact O-N 3.42Å; T332-E362 HydrophobicContact CG2-CB 4.29Å; T332-E362 VanDerWaalsContact CG2-O 3.26Å; T332-E362 WeakPolarHBondContact CG2-O 3.4Å; T332-E362 VanDerWaalsContact CG2-OE2 3.31Å; T332-E362 WeakPolarHBondContact CG2-OE2 3.44Å; T332-I365 HydrophobicContact CG2-CB 4.32Å; T332-I365 HydrophobicContact CG2-CG2 4.16Å; T332-D366 HydrophobicContact CG2-CB 3.92Å; T332-H369 PolarHBondContact OG1-ND1 3.2Å
333	A	97.7	Very high	96.4	Very high	18 Å²	18	64.6 Å²	64.6	15%	0.149	34%	0.335	C	S	.	.	H	α-helix	trans	-62.5	-38.1	176.6	0	0	0	0	0	112.5	S329 V330 N331 K337 D366	S329-A333 PolarHBondContact O-N 3.17Å; V330-A333 PolarHBondContact O-N 3.44Å; N331-A333 VanDerWaalsContact C-N 3.34Å; N331-A333 PolarHBondContact O-N 2.91Å; A333-K337 WeakPolarHBondContact O-CG 3.2Å; A333-K337 PolarHBondContact O-N 3.24Å; A333-D366 HydrophobicContact CB-CB 4.34Å; A333-D366 WeakPolarHBondContact CB-OD2 3.27Å
334	Q	97.9	Very high	96.5	Very high	108 Å²	108	67.6 Å²	67.6	51%	0.505	35%	0.347	S	S	.	.	H	α-helix	trans	-68	-40.1	175.3	-71.6	175.2	7.4	0	0	112	V330 N331 T332 K337 S338	V330-Q334 WeakPolarHBondContact O-CG 3.32Å; V330-Q334 PolarHBondContact O-N 3.28Å; N331-Q334 PolarHBondContact O-N 2.99Å; T332-Q334 VanDerWaalsContact C-N 3.32Å; T332-Q334 PolarHBondContact O-N 2.9Å; Q334-K337 PolarHBondContact O-N 2.68Å; Q334-S338 WeakPolarHBondContact O-CB 3.25Å; Q334-S338 PolarHBondContact O-N 2.67Å; Q334-S338 PolarHBondContact O-OG 3.09Å
335	F	98.2	Very high	96.5	Very high	99 Å²	99	66.3 Å²	66.3	43%	0.434	35%	0.35	S	S	.	.	H	α-helix	trans	-62.1	-46.9	174.7	178.2	-107.1	0	0	0	111.4	N331 T332 K337 S338 A339 L358 E362	N331-F335 PolarHBondContact O-N 2.66Å; T332-F335 PolarHBondContact O-N 3.48Å; F335-K337 VanDerWaalsContact C-N 3.34Å; F335-K337 PolarHBondContact O-N 2.94Å; F335-S338 WeakPolarHBondContact O-CB 3.08Å; F335-S338 PolarHBondContact O-N 3.39Å; F335-A339 PolarHBondContact O-N 3.42Å; F335-L358 HydrophobicContact CE1-CD2 4.3Å; F335-L358 HydrophobicContact CE1-CG 4.42Å; F335-L358 HydrophobicContact CZ-CD2 4.21Å; F335-E362 HydrophobicContact CD1-CB 4.26Å; F335-E362 HydrophobicContact CD1-CG 3.64Å; F335-E362 HydrophobicContact CE1-CG 3.7Å; F335-E362 WeakPolarHBondContact CE1-OE1 3.5Å
336	A	98.2	Very high	96.4	Very high	0 Å²	0	67.2 Å²	67.2	0%	0	36%	0.356	C	S	.	.	H	α-helix	trans	-55	-48.1	176.6	0	0	0	0	0	112.2	T332 S338 A339 A340 A359 E362 E363	T332-A336 PolarHBondContact O-N 3.42Å; A336-S338 VanDerWaalsContact C-N 3.32Å; A336-S338 PolarHBondContact O-N 2.95Å; A336-A339 PolarHBondContact O-N 2.92Å; A336-A340 PolarHBondContact O-N 2.96Å; A336-A359 WeakPolarHBondContact O-CB 3.46Å; A336-E362 HydrophobicContact CB-CB 3.68Å; A336-E363 HydrophobicContact CB-CG 3.82Å
337	K	97.8	Very high	96.4	Very high	128 Å²	128	71.4 Å²	71.4	56%	0.557	38%	0.382	S	S	*	.	H	α-helix	trans	-59.4	-42.7	175.7	-71.1	169.3	-173.8	173.8	0	112.2	A333 Q334 F335 A340 M341	A333-K337 WeakPolarHBondContact O-CG 3.2Å; A333-K337 PolarHBondContact O-N 3.24Å; Q334-K337 PolarHBondContact O-N 2.68Å; F335-K337 VanDerWaalsContact C-N 3.34Å; F335-K337 PolarHBondContact O-N 2.94Å; K337-A340 PolarHBondContact O-N 3.38Å; K337-M341 WeakPolarHBondContact O-CG 3.36Å; K337-M341 PolarHBondContact O-N 2.92Å
338	S	97.8	Very high	96.3	Very high	71 Å²	71	71.4 Å²	71.4	50%	0.497	38%	0.382	S	S	.	.	H	α-helix	trans	-66.8	-41.6	179.7	-55.7	0	0	0	0	111.6	Q334 F335 A336 M341 L342	Q334-S338 WeakPolarHBondContact O-CB 3.25Å; Q334-S338 PolarHBondContact O-N 2.67Å; Q334-S338 PolarHBondContact O-OG 3.09Å; F335-S338 WeakPolarHBondContact O-CB 3.08Å; F335-S338 PolarHBondContact O-N 3.39Å; A336-S338 VanDerWaalsContact C-N 3.32Å; A336-S338 PolarHBondContact O-N 2.95Å; S338-M341 PolarHBondContact O-N 3.33Å; S338-L342 PolarHBondContact O-N 2.84Å
339	A	96.9	Very high	96	Very high	7 Å²	7	73.3 Å²	73.3	6%	0.058	40%	0.397	C	S	.	.	H	α-helix	trans	-62.8	-40.6	174.8	0	0	0	0	0	111.8	F335 A336 L342 G343 A359	F335-A339 PolarHBondContact O-N 3.42Å; A336-A339 PolarHBondContact O-N 2.92Å; A339-L342 PolarHBondContact O-N 2.65Å; A339-G343 PolarHBondContact O-N 3.14Å; A339-A359 HydrophobicContact CB-CB 4.09Å
340	A	97.1	Very high	95.6	Very high	30 Å²	30	74.9 Å²	74.9	25%	0.248	41%	0.41	C	S	.	.	H	α-helix	trans	-63.8	-43.1	174.8	0	0	0	0	0	112	A336 K337 G343 N344 A359	A336-A340 PolarHBondContact O-N 2.96Å; K337-A340 PolarHBondContact O-N 3.38Å; A340-G343 PolarHBondContact O-N 2.93Å; A340-N344 VanDerWaalsContact O-CG 3.32Å; A340-N344 PolarHBondContact O-N 3.19Å; A340-N344 PolarHBondContact O-ND2 3.3Å; A340-A359 HydrophobicContact CB-CB 3.74Å
341	M	96.8	Very high	95.5	Very high	135 Å²	135	73.8 Å²	73.8	67%	0.665	40%	0.401	S	S	*	.	H	α-helix	trans	-61.4	-43.7	175.2	-72	179.8	-176.7	0	0	111.6	K337 S338 N344 S345	K337-M341 WeakPolarHBondContact O-CG 3.36Å; K337-M341 PolarHBondContact O-N 2.92Å; S338-M341 PolarHBondContact O-N 3.33Å; M341-N344 PolarHBondContact O-N 3.12Å; M341-S345 PolarHBondContact O-N 2.9Å; M341-S345 VanDerWaalsContact O-N 3.14Å; M341-S345 PolarHBondContact O-OG 3.15Å
342	L	95.5	Very high	95.3	Very high	94 Å²	94	70.7 Å²	70.7	49%	0.492	39%	0.387	S	S	.	.	H	α-helix	trans	-63.4	-43.4	177.2	-171.7	64.5	0	0	0	111.3	S338 A339 N344 S345 E346 L355	S338-L342 PolarHBondContact O-N 2.84Å; A339-L342 PolarHBondContact O-N 2.65Å; L342-N344 VanDerWaalsContact C-N 3.27Å; L342-N344 PolarHBondContact O-N 3.37Å; L342-S345 WeakPolarHBondContact CA-OG 3.41Å; L342-S345 PolarHBondContact O-N 3.08Å; L342-S345 PolarHBondContact O-OG 2.89Å; L342-E346 PolarHBondContact O-N 3.28Å; L342-E346 VanDerWaalsContact O-N 3.12Å; L342-L355 HydrophobicContact CB-CD1 4.28Å; L342-L355 HydrophobicContact CD2-CD1 3.96Å; L342-L355 HydrophobicContact CD2-CD2 4.13Å; L342-L355 HydrophobicContact CG-CD1 3.81Å
343	G	94.9	Very high	95	Very high	0 Å²	0	76.7 Å²	76.7	0%	0	41%	0.408	C	S	.	.	H	α-helix	trans	-58.8	-37.4	175.3	0	0	0	0	0	112.9	A339 A340 S345 E346 S352	A339-G343 PolarHBondContact O-N 3.14Å; A340-G343 PolarHBondContact O-N 2.93Å; G343-S345 VanDerWaalsContact C-N 3.33Å; G343-E346 PolarHBondContact O-N 3.28Å; G343-S352 VanDerWaalsContact O-CB 3.3Å; G343-S352 WeakPolarHBondContact O-CB 3.26Å; G343-S352 PolarHBondContact O-OG 3.13Å
344	N	94	Very high	94.8	Very high	131 Å²	131	76 Å²	76	70%	0.701	40%	0.402	S	S	*	.	H	α-helix	trans	-72.2	-24.6	176.1	-70.4	-24.1	0	0	0	113.7	A340 M341 L342	A340-N344 VanDerWaalsContact O-CG 3.32Å; A340-N344 PolarHBondContact O-N 3.19Å; A340-N344 PolarHBondContact O-ND2 3.3Å; M341-N344 PolarHBondContact O-N 3.12Å; L342-N344 VanDerWaalsContact C-N 3.27Å; L342-N344 PolarHBondContact O-N 3.37Å
345	S	94.6	Very high	94.7	Very high	80 Å²	80	72 Å²	72	56%	0.559	38%	0.384	S	S	*	.	H	α-helix	trans	-89.2	-9.4	177.4	62.2	0	0	0	0	114	M341 L342 G343	M341-S345 PolarHBondContact O-N 2.9Å; M341-S345 VanDerWaalsContact O-N 3.14Å; M341-S345 PolarHBondContact O-OG 3.15Å; L342-S345 WeakPolarHBondContact CA-OG 3.41Å; L342-S345 PolarHBondContact O-N 3.08Å; L342-S345 PolarHBondContact O-OG 2.89Å; G343-S345 VanDerWaalsContact C-N 3.33Å
346	E	94.3	Very high	94.5	Very high	65 Å²	65	69.6 Å²	69.6	30%	0.304	38%	0.38	S	S	.	.			trans	-86.6	127.5	-174.5	178.4	57.2	-118	0	0	111.8	L342 G343 H348 L351	L342-E346 PolarHBondContact O-N 3.28Å; L342-E346 VanDerWaalsContact O-N 3.12Å; G343-E346 PolarHBondContact O-N 3.28Å; E346-H348 HydrophobicContact CG-CB 4.31Å; E346-H348 WeakPolarHBondContact OE1-CB 3.48Å; E346-H348 PolarHBondContact OE1-N 2.99Å; E346-L351 HydrophobicContact CG-CB 3.95Å; E346-L351 HydrophobicContact CG-CD2 3.92Å; E346-L351 HydrophobicContact CG-CG 3.85Å; E346-L351 WeakPolarHBondContact OE2-CD2 3.45Å
347	D	92.7	Very high	94.4	Very high	158 Å²	158	71.4 Å²	71.4	85%	0.845	39%	0.388	S	S	*	.			trans	-78.7	-31.1	179.7	-69.4	-39.9	0	0	0	112	T349	D347-T349 PolarHBondContact O-N 3Å; D347-T349 VanDerWaalsContact O-N 3.11Å
348	H	91.7	Very high	94.4	Very high	109 Å²	109	66.7 Å²	66.7	51%	0.505	37%	0.369	S	S	.	.	S	Bend	trans	-73.3	105.7	179.2	-170.3	-92.2	0	0	0	110.9	E346 A350 L351 S352	E346-H348 HydrophobicContact CG-CB 4.31Å; E346-H348 WeakPolarHBondContact OE1-CB 3.48Å; E346-H348 PolarHBondContact OE1-N 2.99Å; H348-A350 VanDerWaalsContact C-N 3.3Å; H348-A350 PolarHBondContact O-N 3.15Å; H348-A350 VanDerWaalsContact O-N 3.12Å; H348-L351 HydrophobicContact CB-CB 4.12Å; H348-L351 PolarHBondContact ND1-N 3.1Å; H348-L351 PolarHBondContact O-N 3.34Å; H348-S352 PolarHBondContact O-N 2.76Å
349	T	90.6	Very high	94.4	Very high	118 Å²	118	63.5 Å²	63.5	72%	0.724	35%	0.347	S	S	*	.	H	α-helix	trans	-54	-39.7	-170.9	-48.2	0	0	0	0	114.3	D347 R353	D347-T349 PolarHBondContact O-N 3Å; D347-T349 VanDerWaalsContact O-N 3.11Å; T349-R353 WeakPolarHBondContact O-CB 3.38Å; T349-R353 PolarHBondContact O-N 2.99Å
350	A	90	Very high	94.4	Very high	41 Å²	41	67.9 Å²	67.9	34%	0.339	37%	0.366	S	S	.	.	H	α-helix	trans	-70.4	-35.4	179.2	0	0	0	0	0	112.3	H348 A354	H348-A350 VanDerWaalsContact C-N 3.3Å; H348-A350 PolarHBondContact O-N 3.15Å; H348-A350 VanDerWaalsContact O-N 3.12Å; A350-A354 WeakPolarHBondContact O-CB 3.49Å; A350-A354 PolarHBondContact O-N 3.19Å; A350-A354 VanDerWaalsContact O-N 3.09Å
351	L	92.3	Very high	94.4	Very high	53 Å²	53	67 Å²	67	28%	0.277	36%	0.358	S	S	.	.	H	α-helix	trans	-74.5	-43.7	178	178.3	58.6	0	0	0	110.5	E346 H348 R353 A354 L355 I513	E346-L351 HydrophobicContact CG-CB 3.95Å; E346-L351 HydrophobicContact CG-CD2 3.92Å; E346-L351 HydrophobicContact CG-CG 3.85Å; E346-L351 WeakPolarHBondContact OE2-CD2 3.45Å; H348-L351 HydrophobicContact CB-CB 4.12Å; H348-L351 PolarHBondContact ND1-N 3.1Å; H348-L351 PolarHBondContact O-N 3.34Å; L351-R353 PolarHBondContact O-N 3.39Å; L351-A354 PolarHBondContact O-N 2.87Å; L351-L355 HydrophobicContact CD1-CD1 4.31Å; L351-L355 HydrophobicContact CD1-CG 4.3Å; L351-L355 HydrophobicContact CG-CD1 4.16Å; L351-L355 WeakPolarHBondContact O-CG 3.32Å; L351-L355 PolarHBondContact O-N 2.8Å; L351-I513 HydrophobicContact CB-CG2 4.49Å; L351-I513 HydrophobicContact CD1-CD1 4.19Å; L351-I513 HydrophobicContact CD1-CG2 4.01Å
352	S	93.5	Very high	94.5	Very high	27 Å²	27	61.7 Å²	61.7	19%	0.189	33%	0.331	C	S	.	.	H	α-helix	trans	-52.5	-51.6	171.6	173.1	0	0	0	0	111.4	G343 H348 A354 L355 S356	G343-S352 VanDerWaalsContact O-CB 3.3Å; G343-S352 WeakPolarHBondContact O-CB 3.26Å; G343-S352 PolarHBondContact O-OG 3.13Å; H348-S352 PolarHBondContact O-N 2.76Å; S352-A354 PolarHBondContact O-N 3.29Å; S352-L355 PolarHBondContact O-N 3.25Å; S352-S356 PolarHBondContact O-N 2.96Å; S352-S356 PolarHBondContact O-OG 3.22Å
353	R	92.1	Very high	94.6	Very high	139 Å²	139	62.4 Å²	62.4	53%	0.525	33%	0.332	S	S	.	.	H	α-helix	trans	-57.9	-45.8	176.8	179.2	-176	171.2	85.4	1.9	112.3	T349 L351 S356 Q357 E509	T349-R353 WeakPolarHBondContact O-CB 3.38Å; T349-R353 PolarHBondContact O-N 2.99Å; L351-R353 PolarHBondContact O-N 3.39Å; R353-S356 PolarHBondContact O-N 3.47Å; R353-Q357 VanDerWaalsContact CZ-NE2 3.32Å; R353-Q357 VanDerWaalsContact NH2-NE2 3.16Å; R353-Q357 WeakPolarHBondContact O-CG 3.47Å; R353-Q357 PolarHBondContact O-N 2.9Å; R353-E509 IonicContact CZ-OE1 3.49Å; R353-E509 IonicContact NE-OE1 3.26Å; R353-E509 PolarHBondContact NE-OE1 3.07Å; R353-E509 IonicContact NE-OE2 3.14Å; R353-E509 PolarHBondContact NE-OE2 2.95Å; R353-E509 VanDerWaalsContact NE-OE2 3.14Å; R353-E509 IonicContact NH2-OE1 2.84Å; R353-E509 PolarHBondContact NH2-OE1 3.44Å
354	A	94.4	Very high	94.8	Very high	3 Å²	3	66.2 Å²	66.2	3%	0.025	35%	0.349	C	S	.	.	H	α-helix	trans	-67.1	-37.1	-178.9	0	0	0	0	0	112.7	A350 L351 S352 Q357 L358 I513	A350-A354 WeakPolarHBondContact O-CB 3.49Å; A350-A354 PolarHBondContact O-N 3.19Å; A350-A354 VanDerWaalsContact O-N 3.09Å; L351-A354 PolarHBondContact O-N 2.87Å; S352-A354 PolarHBondContact O-N 3.29Å; A354-Q357 PolarHBondContact O-N 3.12Å; A354-L358 WeakPolarHBondContact O-CB 3.21Å; A354-L358 PolarHBondContact O-N 3.45Å; A354-I513 HydrophobicContact CB-CD1 3.17Å; A354-I513 HydrophobicContact CB-CG1 3.7Å
355	L	95.3	Very high	94.9	Very high	25 Å²	25	60.3 Å²	60.3	13%	0.131	32%	0.317	C	S	.	.	H	α-helix	trans	-65.4	-40.8	173.7	-74.3	169.7	0	0	0	112.1	L342 L351 S352 Q357 L358 A359	L342-L355 HydrophobicContact CB-CD1 4.28Å; L342-L355 HydrophobicContact CD2-CD1 3.96Å; L342-L355 HydrophobicContact CD2-CD2 4.13Å; L342-L355 HydrophobicContact CG-CD1 3.81Å; L351-L355 HydrophobicContact CD1-CD1 4.31Å; L351-L355 HydrophobicContact CD1-CG 4.3Å; L351-L355 HydrophobicContact CG-CD1 4.16Å; L351-L355 WeakPolarHBondContact O-CG 3.32Å; L351-L355 PolarHBondContact O-N 2.8Å; S352-L355 PolarHBondContact O-N 3.25Å; L355-Q357 VanDerWaalsContact C-N 3.34Å; L355-Q357 PolarHBondContact O-N 2.99Å; L355-L358 PolarHBondContact O-N 3.43Å; L355-A359 PolarHBondContact O-N 2.68Å
356	S	94.8	Very high	95.1	Very high	48 Å²	48	57.5 Å²	57.5	34%	0.336	30%	0.296	S	S	.	.	H	α-helix	trans	-63.1	-39.4	173.6	-58.8	0	0	0	0	112.3	S352 R353 A359 E360	S352-S356 PolarHBondContact O-N 2.96Å; S352-S356 PolarHBondContact O-OG 3.22Å; R353-S356 PolarHBondContact O-N 3.47Å; S356-A359 WeakPolarHBondContact O-CB 3.3Å; S356-A359 PolarHBondContact O-N 3.32Å; S356-E360 PolarHBondContact O-N 3.2Å; S356-E360 VanDerWaalsContact O-N 3.11Å
357	Q	95.4	Very high	95.2	Very high	37 Å²	37	58.8 Å²	58.8	17%	0.173	30%	0.302	C	S	.	.	H	α-helix	trans	-71.5	-36.6	175.9	-72.3	-171.4	24.9	0	0	113	R353 A354 L355 A359 E360 V361 F506 E509	R353-Q357 VanDerWaalsContact CZ-NE2 3.32Å; R353-Q357 VanDerWaalsContact NH2-NE2 3.16Å; R353-Q357 WeakPolarHBondContact O-CG 3.47Å; R353-Q357 PolarHBondContact O-N 2.9Å; A354-Q357 PolarHBondContact O-N 3.12Å; L355-Q357 VanDerWaalsContact C-N 3.34Å; L355-Q357 PolarHBondContact O-N 2.99Å; Q357-A359 VanDerWaalsContact C-N 3.27Å; Q357-A359 PolarHBondContact O-N 2.95Å; Q357-E360 PolarHBondContact O-N 2.79Å; Q357-V361 VanDerWaalsContact O-CG2 3.25Å; Q357-V361 WeakPolarHBondContact O-CG2 3.37Å; Q357-V361 PolarHBondContact O-N 2.94Å; Q357-F506 HydrophobicContact CB-CD2 4.2Å; Q357-F506 HydrophobicContact CB-CE2 4.1Å; Q357-E509 PolarHBondContact NE2-OE1 3.42Å; Q357-E509 PolarHBondContact NE2-OE2 3.11Å; Q357-E509 VanDerWaalsContact OE1-CD 3.28Å; Q357-E509 PolarHBondContact OE1-OE1 3.42Å
358	L	97	Very high	95.4	Very high	30 Å²	30	52 Å²	52	16%	0.157	27%	0.265	C	S	.	.	H	α-helix	trans	-58.8	-44.2	171.8	178.5	61.4	0	0	0	110.2	F335 A354 L355 E360 V361 E362 W503 F506	F335-L358 HydrophobicContact CE1-CD2 4.3Å; F335-L358 HydrophobicContact CE1-CG 4.42Å; F335-L358 HydrophobicContact CZ-CD2 4.21Å; A354-L358 WeakPolarHBondContact O-CB 3.21Å; A354-L358 PolarHBondContact O-N 3.45Å; L355-L358 PolarHBondContact O-N 3.43Å; L358-E360 PolarHBondContact O-N 3.34Å; L358-V361 PolarHBondContact O-N 3.3Å; L358-E362 HydrophobicContact CD1-CG 4.12Å; L358-E362 HydrophobicContact CG-CG 4.39Å; L358-E362 WeakPolarHBondContact O-CB 3.48Å; L358-E362 VanDerWaalsContact O-CG 3.26Å; L358-E362 WeakPolarHBondContact O-CG 3.4Å; L358-E362 PolarHBondContact O-N 3.35Å; L358-W503 HydrophobicContact CD1-CH2 4.16Å; L358-W503 HydrophobicContact CD1-CZ3 4.14Å; L358-F506 HydrophobicContact CB-CE1 4.5Å; L358-F506 HydrophobicContact CB-CE2 3.94Å; L358-F506 HydrophobicContact CB-CZ 3.75Å; L358-F506 HydrophobicContact CD1-CD1 4.49Å; L358-F506 HydrophobicContact CD1-CE1 3.9Å; L358-F506 HydrophobicContact CD1-CZ 4.01Å; L358-F506 HydrophobicContact CG-CZ 4.38Å
359	A	97.8	Very high	95.6	Very high	4 Å²	4	48 Å²	48	3%	0.033	25%	0.247	C	C	.	.	H	α-helix	trans	-58.1	-46.7	174.9	0	0	0	0	0	112.1	A336 A339 A340 L355 S356 Q357 V361 E362 E363	A336-A359 WeakPolarHBondContact O-CB 3.46Å; A339-A359 HydrophobicContact CB-CB 4.09Å; A340-A359 HydrophobicContact CB-CB 3.74Å; L355-A359 PolarHBondContact O-N 2.68Å; S356-A359 WeakPolarHBondContact O-CB 3.3Å; S356-A359 PolarHBondContact O-N 3.32Å; Q357-A359 VanDerWaalsContact C-N 3.27Å; Q357-A359 PolarHBondContact O-N 2.95Å; A359-V361 VanDerWaalsContact C-N 3.33Å; A359-V361 PolarHBondContact O-N 3.03Å; A359-E362 PolarHBondContact O-N 2.84Å; A359-E363 WeakPolarHBondContact O-CG 3.24Å; A359-E363 PolarHBondContact O-N 3.37Å
360	E	97.3	Very high	95.8	Very high	98 Å²	98	45.8 Å²	45.8	46%	0.458	23%	0.228	S	C	.	.	H	α-helix	trans	-62.8	-38	177.5	-167.4	-168	152.7	0	0	112.5	S356 Q357 L358 K364	S356-E360 PolarHBondContact O-N 3.2Å; S356-E360 VanDerWaalsContact O-N 3.11Å; Q357-E360 PolarHBondContact O-N 2.79Å; L358-E360 PolarHBondContact O-N 3.34Å; E360-K364 WeakPolarHBondContact O-CG 3.39Å; E360-K364 PolarHBondContact O-N 2.81Å; E360-K364 WeakPolarHBondContact OE1-CE 3.29Å; E360-K364 IonicContact OE1-NZ 2.87Å; E360-K364 PolarHBondContact OE1-NZ 3.36Å
361	V	98.1	Very high	96	Very high	13 Å²	13	47.3 Å²	47.3	8%	0.079	23%	0.231	C	C	.	.	H	α-helix	trans	-64.6	-46.2	175.6	168.8	0	0	0	0	110.3	Q357 L358 A359 K364 I365 F506	Q357-V361 VanDerWaalsContact O-CG2 3.25Å; Q357-V361 WeakPolarHBondContact O-CG2 3.37Å; Q357-V361 PolarHBondContact O-N 2.94Å; L358-V361 PolarHBondContact O-N 3.3Å; A359-V361 VanDerWaalsContact C-N 3.33Å; A359-V361 PolarHBondContact O-N 3.03Å; V361-K364 WeakPolarHBondContact O-CB 3.34Å; V361-K364 PolarHBondContact O-N 3.03Å; V361-K364 VanDerWaalsContact O-N 3.14Å; V361-I365 HydrophobicContact CG1-CD1 3.84Å; V361-I365 HydrophobicContact CG1-CG1 4.45Å; V361-I365 VanDerWaalsContact O-CG1 3.31Å; V361-I365 WeakPolarHBondContact O-CG1 3.37Å; V361-I365 PolarHBondContact O-N 3.31Å; V361-F506 HydrophobicContact CG2-CB 3.89Å; V361-F506 HydrophobicContact CG2-CD2 4.19Å; V361-F506 HydrophobicContact CG2-CG 4.19Å
362	E	98.1	Very high	96.2	Very high	23 Å²	23	46 Å²	46	11%	0.107	22%	0.223	C	C	.	.	H	α-helix	trans	-66.7	-35.3	178.9	-67.6	-75.5	-176	0	0	112.1	T332 F335 A336 L358 A359 K364 I365 D366	T332-E362 HydrophobicContact CG2-CB 4.29Å; T332-E362 VanDerWaalsContact CG2-O 3.26Å; T332-E362 WeakPolarHBondContact CG2-O 3.4Å; T332-E362 VanDerWaalsContact CG2-OE2 3.31Å; T332-E362 WeakPolarHBondContact CG2-OE2 3.44Å; F335-E362 HydrophobicContact CD1-CB 4.26Å; F335-E362 HydrophobicContact CD1-CG 3.64Å; F335-E362 HydrophobicContact CE1-CG 3.7Å; F335-E362 WeakPolarHBondContact CE1-OE1 3.5Å; A336-E362 HydrophobicContact CB-CB 3.68Å; L358-E362 HydrophobicContact CD1-CG 4.12Å; L358-E362 HydrophobicContact CG-CG 4.39Å; L358-E362 WeakPolarHBondContact O-CB 3.48Å; L358-E362 VanDerWaalsContact O-CG 3.26Å; L358-E362 WeakPolarHBondContact O-CG 3.4Å; L358-E362 PolarHBondContact O-N 3.35Å; A359-E362 PolarHBondContact O-N 2.84Å; E362-K364 VanDerWaalsContact C-N 3.31Å; E362-K364 PolarHBondContact O-N 3.42Å; E362-I365 PolarHBondContact O-N 3.09Å; E362-D366 PolarHBondContact O-N 3.37Å
363	E	98.1	Very high	96.2	Very high	109 Å²	109	44.8 Å²	44.8	51%	0.509	22%	0.215	S	C	.	.	H	α-helix	trans	-60.1	-40.4	170.1	-75.3	-177.2	172.3	0	0	112	A336 A359 I365 D366 Q367	A336-E363 HydrophobicContact CB-CG 3.82Å; A359-E363 WeakPolarHBondContact O-CG 3.24Å; A359-E363 PolarHBondContact O-N 3.37Å; E363-I365 VanDerWaalsContact C-N 3.35Å; E363-D366 PolarHBondContact O-N 3.08Å; E363-Q367 PolarHBondContact O-N 3.47Å
364	K	98	Very high	96.1	Very high	80 Å²	80	41.2 Å²	41.2	35%	0.348	21%	0.206	S	C	.	.	H	α-helix	trans	-68.9	-34.4	175.4	-68.3	169.9	-174	161.4	0	112	E360 V361 E362 L368 Y502	E360-K364 WeakPolarHBondContact O-CG 3.39Å; E360-K364 PolarHBondContact O-N 2.81Å; E360-K364 WeakPolarHBondContact OE1-CE 3.29Å; E360-K364 IonicContact OE1-NZ 2.87Å; E360-K364 PolarHBondContact OE1-NZ 3.36Å; V361-K364 WeakPolarHBondContact O-CB 3.34Å; V361-K364 PolarHBondContact O-N 3.03Å; V361-K364 VanDerWaalsContact O-N 3.14Å; E362-K364 VanDerWaalsContact C-N 3.31Å; E362-K364 PolarHBondContact O-N 3.42Å; K364-L368 PolarHBondContact O-N 2.69Å; K364-Y502 HydrophobicContact CB-CD2 3.85Å; K364-Y502 HydrophobicContact CB-CE1 4.4Å; K364-Y502 HydrophobicContact CB-CE2 3.53Å; K364-Y502 HydrophobicContact CB-CG 4.43Å; K364-Y502 HydrophobicContact CD-CD1 4.31Å; K364-Y502 HydrophobicContact CD-CE1 4.06Å
365	I	98.1	Very high	96.1	Very high	6 Å²	6	41.6 Å²	41.6	3%	0.031	21%	0.209	C	C	.	.	H	α-helix	trans	-70.2	-40.2	175.8	-67	172.1	0	0	0	110.9	T332 V361 E362 E363 Q367 L368 H369 L499 Y502 W503	T332-I365 HydrophobicContact CG2-CB 4.32Å; T332-I365 HydrophobicContact CG2-CG2 4.16Å; V361-I365 HydrophobicContact CG1-CD1 3.84Å; V361-I365 HydrophobicContact CG1-CG1 4.45Å; V361-I365 VanDerWaalsContact O-CG1 3.31Å; V361-I365 WeakPolarHBondContact O-CG1 3.37Å; V361-I365 PolarHBondContact O-N 3.31Å; E362-I365 PolarHBondContact O-N 3.09Å; E363-I365 VanDerWaalsContact C-N 3.35Å; I365-Q367 VanDerWaalsContact C-N 3.32Å; I365-Q367 PolarHBondContact O-N 3.14Å; I365-L368 WeakPolarHBondContact O-CB 3.42Å; I365-L368 PolarHBondContact O-N 3.3Å; I365-L368 VanDerWaalsContact O-N 3.11Å; I365-H369 VanDerWaalsContact CG2-CE1 3.48Å; I365-H369 WeakPolarHBondContact CG2-CE1 3.39Å; I365-H369 PolarHBondContact O-N 3.36Å; I365-L499 HydrophobicContact CB-CD1 4.41Å; I365-L499 HydrophobicContact CD1-CD1 3.65Å; I365-L499 HydrophobicContact CG1-CD1 3.56Å; I365-L499 HydrophobicContact CG2-CD1 4.04Å; I365-Y502 HydrophobicContact CG1-CD2 4.27Å; I365-W503 HydrophobicContact CD1-CH2 4.49Å; I365-W503 HydrophobicContact CD1-CZ2 3.56Å
366	D	97.6	Very high	96	Very high	21 Å²	21	40.4 Å²	40.4	11%	0.112	20%	0.203	C	C	.	.	H	α-helix	trans	-53.7	-50.2	171.2	167.5	36.5	0	0	0	110.6	S329 T332 A333 E362 E363 L368 H369 Q370	S329-D366 WeakPolarHBondContact CA-OD1 3.48Å; S329-D366 VanDerWaalsContact CB-OD1 3.28Å; S329-D366 WeakPolarHBondContact CB-OD1 3.29Å; S329-D366 VanDerWaalsContact O-OD1 3.04Å; S329-D366 PolarHBondContact OG-OD1 3.2Å; T332-D366 HydrophobicContact CG2-CB 3.92Å; A333-D366 HydrophobicContact CB-CB 4.34Å; A333-D366 WeakPolarHBondContact CB-OD2 3.27Å; E362-D366 PolarHBondContact O-N 3.37Å; E363-D366 PolarHBondContact O-N 3.08Å; D366-L368 VanDerWaalsContact C-N 3.28Å; D366-L368 PolarHBondContact O-N 3.26Å; D366-H369 WeakPolarHBondContact O-CB 3.21Å; D366-H369 PolarHBondContact O-N 3.35Å; D366-Q370 WeakPolarHBondContact O-CG 3.48Å; D366-Q370 PolarHBondContact O-N 3.05Å; D366-Q370 PolarHBondContact OD1-NE2 3.3Å; D366-Q370 PolarHBondContact OD2-NE2 2.95Å; D366-Q370 VanDerWaalsContact OD2-NE2 3.14Å
367	Q	96.5	Very high	95.8	Very high	93 Å²	93	38.7 Å²	38.7	44%	0.435	19%	0.19	S	C	.	.	H	α-helix	trans	-57.8	-40.6	176.9	-172.1	60	59.9	0	0	112.3	E363 I365 H369 Q370 D371	E363-Q367 PolarHBondContact O-N 3.47Å; I365-Q367 VanDerWaalsContact C-N 3.32Å; I365-Q367 PolarHBondContact O-N 3.14Å; Q367-H369 PolarHBondContact O-N 3.46Å; Q367-Q370 PolarHBondContact O-N 3.24Å; Q367-D371 PolarHBondContact NE2-OD1 3.25Å; Q367-D371 VanDerWaalsContact O-CG 3.26Å; Q367-D371 PolarHBondContact O-N 3Å
368	L	96.6	Very high	95.4	Very high	15 Å²	15	40.7 Å²	40.7	8%	0.079	20%	0.196	C	C	.	.	H	α-helix	trans	-62.9	-40.5	174.8	-73.1	-178	0	0	0	112.5	K364 I365 D366 Q370 D371 Q372 T495 Q498 L499 Y502	K364-L368 PolarHBondContact O-N 2.69Å; I365-L368 WeakPolarHBondContact O-CB 3.42Å; I365-L368 PolarHBondContact O-N 3.3Å; I365-L368 VanDerWaalsContact O-N 3.11Å; D366-L368 VanDerWaalsContact C-N 3.28Å; D366-L368 PolarHBondContact O-N 3.26Å; L368-Q370 VanDerWaalsContact C-N 3.34Å; L368-D371 PolarHBondContact O-N 3.42Å; L368-Q372 VanDerWaalsContact O-CB 3.32Å; L368-Q372 WeakPolarHBondContact O-CB 3.26Å; L368-Q372 PolarHBondContact O-N 2.95Å; L368-T495 HydrophobicContact CB-CG2 4.01Å; L368-T495 HydrophobicContact CD2-CG2 4.29Å; L368-Q498 HydrophobicContact CD1-CB 3.99Å; L368-Q498 HydrophobicContact CD1-CG 4.09Å; L368-Q498 HydrophobicContact CD2-CB 4.07Å; L368-Q498 HydrophobicContact CD2-CG 3.99Å; L368-L499 HydrophobicContact CD1-CB 4.18Å; L368-Y502 HydrophobicContact CD1-CD2 3.77Å; L368-Y502 HydrophobicContact CD1-CE2 3.45Å; L368-Y502 VanDerWaalsContact CD1-CE2 3.45Å; L368-Y502 HydrophobicContact CG-CE2 3.87Å
369	H	96.8	Very high	95.1	Very high	26 Å²	26	40.8 Å²	40.8	12%	0.12	20%	0.197	C	C	.	.	H	α-helix	trans	-63.8	-39.1	175.1	-68.6	154.4	0	0	0	111.7	R325 T332 I365 D366 Q367 Q372 A373	R325-H369 WeakPolarHBondContact CG-O 3.37Å; T332-H369 PolarHBondContact OG1-ND1 3.2Å; I365-H369 VanDerWaalsContact CG2-CE1 3.48Å; I365-H369 WeakPolarHBondContact CG2-CE1 3.39Å; I365-H369 PolarHBondContact O-N 3.36Å; D366-H369 WeakPolarHBondContact O-CB 3.21Å; D366-H369 PolarHBondContact O-N 3.35Å; Q367-H369 PolarHBondContact O-N 3.46Å; H369-Q372 PolarHBondContact O-N 3.35Å; H369-A373 WeakPolarHBondContact O-CB 3.38Å; H369-A373 PolarHBondContact O-N 2.73Å
370	Q	95	Very high	94.9	Very high	70 Å²	70	42.1 Å²	42.1	33%	0.327	20%	0.202	S	C	.	.	H	α-helix	trans	-63.1	-46.7	174.4	-65.7	178.3	25.1	0	0	111.6	S329 D366 Q367 L368 Q372 A373 N374	S329-Q370 WeakPolarHBondContact OG-CG 3.36Å; S329-Q370 PolarHBondContact OG-NE2 3.37Å; D366-Q370 WeakPolarHBondContact O-CG 3.48Å; D366-Q370 PolarHBondContact O-N 3.05Å; D366-Q370 PolarHBondContact OD1-NE2 3.3Å; D366-Q370 PolarHBondContact OD2-NE2 2.95Å; D366-Q370 VanDerWaalsContact OD2-NE2 3.14Å; Q367-Q370 PolarHBondContact O-N 3.24Å; L368-Q370 VanDerWaalsContact C-N 3.34Å; Q370-Q372 VanDerWaalsContact C-N 3.3Å; Q370-Q372 PolarHBondContact O-N 3.07Å; Q370-A373 PolarHBondContact O-N 3.47Å; Q370-N374 VanDerWaalsContact O-CG 3.29Å; Q370-N374 PolarHBondContact O-N 3.41Å; Q370-N374 PolarHBondContact O-ND2 3.47Å
371	D	94	Very high	94.7	Very high	74 Å²	74	37.5 Å²	37.5	40%	0.396	18%	0.18	S	C	.	.	H	α-helix	trans	-61.9	-40.8	178.3	-67.7	-12.6	0	0	0	111.2	Q367 L368 N374 A375	Q367-D371 PolarHBondContact NE2-OD1 3.25Å; Q367-D371 VanDerWaalsContact O-CG 3.26Å; Q367-D371 PolarHBondContact O-N 3Å; L368-D371 PolarHBondContact O-N 3.42Å; D371-N374 WeakPolarHBondContact O-CB 3.1Å; D371-N374 PolarHBondContact O-N 2.96Å; D371-A375 PolarHBondContact O-N 3.08Å
372	Q	95.8	Very high	94.2	Very high	25 Å²	25	37.2 Å²	37.2	12%	0.117	18%	0.178	C	C	.	.	H	α-helix	trans	-66.7	-41.4	176.3	-162.7	173.5	2	0	0	111.8	R325 L368 H369 Q370 N374 A375 D376 L492 T495	R325-Q372 HydrophobicContact CG-CB 4.39Å; L368-Q372 VanDerWaalsContact O-CB 3.32Å; L368-Q372 WeakPolarHBondContact O-CB 3.26Å; L368-Q372 PolarHBondContact O-N 2.95Å; H369-Q372 PolarHBondContact O-N 3.35Å; Q370-Q372 VanDerWaalsContact C-N 3.3Å; Q370-Q372 PolarHBondContact O-N 3.07Å; Q372-N374 VanDerWaalsContact C-N 3.29Å; Q372-N374 PolarHBondContact O-N 3.46Å; Q372-A375 PolarHBondContact O-N 3.21Å; Q372-D376 WeakPolarHBondContact O-CB 3.36Å; Q372-D376 PolarHBondContact O-N 2.86Å; Q372-L492 HydrophobicContact CG-CD2 3.92Å; Q372-T495 HydrophobicContact CB-CG2 4.38Å
373	A	93.7	Very high	93.9	Very high	1 Å²	1	36.8 Å²	36.8	1%	0.008	18%	0.176	C	C	.	.	H	α-helix	trans	-62	-38.4	174.9	0	0	0	0	0	111.8	R325 K326 H369 Q370 L377	R325-A373 HydrophobicContact CB-CB 3.81Å; R325-A373 HydrophobicContact CG-CB 3.82Å; K326-A373 HydrophobicContact CG-CB 3.87Å; H369-A373 WeakPolarHBondContact O-CB 3.38Å; H369-A373 PolarHBondContact O-N 2.73Å; Q370-A373 PolarHBondContact O-N 3.47Å; A373-L377 WeakPolarHBondContact O-CB 3.1Å; A373-L377 PolarHBondContact O-N 2.98Å
374	N	90.9	Very high	93.7	Very high	65 Å²	65	31.6 Å²	31.6	35%	0.348	15%	0.152	S	C	.	.	H	α-helix	trans	-65.9	-41.8	174.4	-71.5	-32.3	0	0	0	111.5	Q370 D371 Q372 L377 Y378	Q370-N374 VanDerWaalsContact O-CG 3.29Å; Q370-N374 PolarHBondContact O-N 3.41Å; Q370-N374 PolarHBondContact O-ND2 3.47Å; D371-N374 WeakPolarHBondContact O-CB 3.1Å; D371-N374 PolarHBondContact O-N 2.96Å; Q372-N374 VanDerWaalsContact C-N 3.29Å; Q372-N374 PolarHBondContact O-N 3.46Å; N374-L377 PolarHBondContact O-N 2.98Å; N374-Y378 HydrophobicContact CB-CD2 4.12Å; N374-Y378 HydrophobicContact CB-CE2 4.28Å; N374-Y378 WeakPolarHBondContact O-CB 3.2Å; N374-Y378 WeakPolarHBondContact O-CD2 3.42Å; N374-Y378 PolarHBondContact O-N 3.49Å
375	A	92.6	Very high	93.4	Very high	11 Å²	11	28 Å²	28	9%	0.091	14%	0.138	C	C	.	.	H	α-helix	trans	-63.8	-46	174.8	0	0	0	0	0	111.9	D371 Q372 L377 L379	D371-A375 PolarHBondContact O-N 3.08Å; Q372-A375 PolarHBondContact O-N 3.21Å; A375-L377 VanDerWaalsContact C-N 3.25Å; A375-L377 PolarHBondContact O-N 2.93Å; A375-L379 HydrophobicContact CB-CD1 4.29Å; A375-L379 VanDerWaalsContact O-CB 3.25Å; A375-L379 WeakPolarHBondContact O-CB 3.28Å; A375-L379 PolarHBondContact O-N 2.85Å
376	D	94.4	Very high	93	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.138	C	C	.	.	I	π-helix	trans	-54.4	-43.8	175	-66.4	-15.7	0	0	0	110.6	V322 R325 Q372 F380 S381 Y488	V322-D376 HydrophobicContact CG2-CB 3.61Å; R325-D376 IonicContact CZ-OD2 3.23Å; R325-D376 VanDerWaalsContact CZ-OD2 3.23Å; R325-D376 IonicContact NE-OD2 3.9Å; R325-D376 PolarHBondContact NE-OD2 2.81Å; R325-D376 IonicContact NH2-OD1 2.81Å; R325-D376 PolarHBondContact NH2-OD1 3.38Å; R325-D376 IonicContact NH2-OD2 2.78Å; R325-D376 PolarHBondContact NH2-OD2 3.47Å; Q372-D376 WeakPolarHBondContact O-CB 3.36Å; Q372-D376 PolarHBondContact O-N 2.86Å; D376-F380 PolarHBondContact O-N 3.03Å; D376-S381 WeakPolarHBondContact O-CB 3.34Å; D376-S381 PolarHBondContact O-N 3.32Å; D376-Y488 WeakPolarHBondContact OD1-CE2 3.44Å; D376-Y488 PolarHBondContact OD1-OH 3.01Å
377	L	90.6	Very high	92.9	Very high	11 Å²	11	27.2 Å²	27.2	6%	0.058	13%	0.133	C	C	.	.	I	π-helix	trans	-72.1	-63.1	179.9	179.5	60.4	0	0	0	112.3	E221 V322 A373 N374 A375 S381 E382	E221-L377 WeakPolarHBondContact OE1-CD2 3.48Å; V322-L377 HydrophobicContact CG1-CB 4.06Å; V322-L377 HydrophobicContact CG1-CD1 4.48Å; V322-L377 HydrophobicContact CG2-CB 4.03Å; A373-L377 WeakPolarHBondContact O-CB 3.1Å; A373-L377 PolarHBondContact O-N 2.98Å; N374-L377 PolarHBondContact O-N 2.98Å; A375-L377 VanDerWaalsContact C-N 3.25Å; A375-L377 PolarHBondContact O-N 2.93Å; L377-S381 WeakPolarHBondContact O-CB 3.31Å; L377-S381 PolarHBondContact O-N 3.32Å; L377-E382 WeakPolarHBondContact O-CG 3.42Å; L377-E382 PolarHBondContact O-N 3.41Å
378	Y	87.6	Confident	92.7	Very high	79 Å²	79	23.8 Å²	23.8	31%	0.31	12%	0.119	S	C	.	.	I	π-helix	trans	-77.8	-30.9	-166.8	-67.8	-64.5	0	0	0	113.7	E224 N374	E224-Y378 HydrophobicContact CG-CE1 4.39Å; N374-Y378 HydrophobicContact CB-CD2 4.12Å; N374-Y378 HydrophobicContact CB-CE2 4.28Å; N374-Y378 WeakPolarHBondContact O-CB 3.2Å; N374-Y378 WeakPolarHBondContact O-CD2 3.42Å; N374-Y378 PolarHBondContact O-N 3.49Å
379	L	90.1	Very high	92.5	Very high	32 Å²	32	26.1 Å²	26.1	17%	0.168	13%	0.126	C	C	.	.	I	π-helix	trans	-87.6	-52.2	177.2	-57.1	179.9	0	0	0	110.5	A375 L383 I484 K487	A375-L379 HydrophobicContact CB-CD1 4.29Å; A375-L379 VanDerWaalsContact O-CB 3.25Å; A375-L379 WeakPolarHBondContact O-CB 3.28Å; A375-L379 PolarHBondContact O-N 2.85Å; L379-L383 VanDerWaalsContact O-CB 3.28Å; L379-L383 WeakPolarHBondContact O-CB 3.32Å; L379-I484 HydrophobicContact CB-CG2 4.26Å; L379-I484 WeakPolarHBondContact O-CG2 3.39Å; L379-K487 HydrophobicContact CD1-CD 4.4Å; L379-K487 HydrophobicContact CD1-CG 4.18Å; L379-K487 HydrophobicContact CD2-CD 4.12Å
380	F	92.9	Very high	92.4	Very high	33 Å²	33	25.1 Å²	25.1	15%	0.145	12%	0.122	C	C	.	.	I	π-helix	trans	-97.2	-56.7	-165.8	-163.7	-156.1	0	0	0	114.1	L314 V318 D376 E382 L383 L384 Y488	L314-F380 HydrophobicContact CD2-CZ 4.43Å; V318-F380 HydrophobicContact CG1-CB 4.36Å; V318-F380 HydrophobicContact CG1-CD1 3.86Å; V318-F380 HydrophobicContact CG1-CG 4.29Å; V318-F380 HydrophobicContact CG2-CD1 3.76Å; V318-F380 HydrophobicContact CG2-CE1 3.6Å; V318-F380 HydrophobicContact CG2-CZ 4.31Å; D376-F380 PolarHBondContact O-N 3.03Å; F380-E382 PolarHBondContact O-N 3Å; F380-L383 PolarHBondContact O-N 3.19Å; F380-L384 HydrophobicContact CD2-CD1 3.86Å; F380-L384 HydrophobicContact CD2-CG 4.02Å; F380-L384 HydrophobicContact CE1-CD1 4.39Å; F380-L384 HydrophobicContact CE2-CD1 3.7Å; F380-L384 HydrophobicContact CE2-CD2 4.15Å; F380-L384 HydrophobicContact CE2-CG 3.92Å; F380-L384 HydrophobicContact CG-CD1 4.28Å; F380-L384 HydrophobicContact CZ-CD1 3.99Å; F380-L384 WeakPolarHBondContact O-CG 3.48Å; F380-L384 PolarHBondContact O-N 2.95Å; F380-Y488 HydrophobicContact CB-CD2 4.27Å; F380-Y488 HydrophobicContact CB-CE2 4.35Å; F380-Y488 HydrophobicContact CB-CG 4.44Å; F380-Y488 HydrophobicContact CD1-CD1 4.36Å; F380-Y488 AromaticContact CD1-CE1 3.93Å; F380-Y488 HydrophobicContact CD1-CE1 3.93Å; F380-Y488 HydrophobicContact CE1-CE1 4.36Å
381	S	92.8	Very high	92.4	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	11%	0.107	C	C	.	.	I	π-helix	trans	-56.5	-50.7	179.4	177.2	0	0	0	0	110.9	H315 D376 L377 L383 L384 G385	H315-S381 PolarHBondContact CD2-O 3.26Å; H315-S381 PolarHBondContact NE2-O 2.75Å; D376-S381 WeakPolarHBondContact O-CB 3.34Å; D376-S381 PolarHBondContact O-N 3.32Å; L377-S381 WeakPolarHBondContact O-CB 3.31Å; L377-S381 PolarHBondContact O-N 3.32Å; S381-L383 VanDerWaalsContact C-N 3.33Å; S381-L383 PolarHBondContact O-N 3.26Å; S381-L384 PolarHBondContact O-N 3.09Å; S381-G385 PolarHBondContact O-N 2.66Å
382	E	88.8	Confident	92.4	Very high	8 Å²	8	20.1 Å²	20.1	4%	0.037	11%	0.106	C	C	.	.	H	α-helix	trans	-62.2	-37.6	-179	-77.2	-57.8	142.1	0	0	112.9	K225 R232 L377 F380 D386	K225-E382 WeakPolarHBondContact CD-OE1 3.36Å; K225-E382 WeakPolarHBondContact CE-OE1 3.46Å; K225-E382 IonicContact NZ-OE1 3.15Å; K225-E382 PolarHBondContact NZ-OE1 3.47Å; R232-E382 IonicContact CZ-OE2 3.5Å; R232-E382 VanDerWaalsContact NH1-C 3.3Å; R232-E382 PolarHBondContact NH1-O 3.17Å; R232-E382 IonicContact NH1-OE2 3.04Å; R232-E382 IonicContact NH2-OE2 3.72Å; R232-E382 PolarHBondContact NH2-OE2 3.44Å; L377-E382 WeakPolarHBondContact O-CG 3.42Å; L377-E382 PolarHBondContact O-N 3.41Å; F380-E382 PolarHBondContact O-N 3Å; E382-D386 WeakPolarHBondContact O-CB 3.28Å; E382-D386 PolarHBondContact O-N 3.12Å; E382-D386 VanDerWaalsContact O-N 3.09Å
383	L	91.1	Very high	92.3	Very high	13 Å²	13	19.7 Å²	19.7	7%	0.068	11%	0.108	C	C	.	.	H	α-helix	trans	-61.7	-49.5	174.3	175.9	75.1	0	0	0	111.2	L379 F380 S381 D386 Y387 F481 I484	L379-L383 VanDerWaalsContact O-CB 3.28Å; L379-L383 WeakPolarHBondContact O-CB 3.32Å; F380-L383 PolarHBondContact O-N 3.19Å; S381-L383 VanDerWaalsContact C-N 3.33Å; S381-L383 PolarHBondContact O-N 3.26Å; L383-D386 WeakPolarHBondContact O-CB 3.38Å; L383-D386 PolarHBondContact O-N 2.87Å; L383-Y387 HydrophobicContact CD1-CD2 3.72Å; L383-Y387 HydrophobicContact CD1-CE2 3.61Å; L383-Y387 HydrophobicContact CG-CD2 4.11Å; L383-Y387 HydrophobicContact CG-CE2 4.44Å; L383-Y387 PolarHBondContact O-N 2.69Å; L383-F481 HydrophobicContact CD2-CD1 3.81Å; L383-F481 HydrophobicContact CD2-CE1 3.95Å; L383-F481 HydrophobicContact CD2-CG 4.19Å; L383-F481 HydrophobicContact CD2-CZ 4.46Å; L383-F481 HydrophobicContact CG-CE1 4.47Å; L383-I484 HydrophobicContact CB-CG2 4.45Å; L383-I484 HydrophobicContact CD1-CG1 4.32Å; L383-I484 HydrophobicContact CD2-CB 3.79Å; L383-I484 HydrophobicContact CD2-CG1 4.23Å; L383-I484 HydrophobicContact CD2-CG2 3.72Å
384	L	93.8	Very high	92.4	Very high	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.107	C	C	.	.	H	α-helix	trans	-60.1	-48.8	-179.2	-73	169.4	0	0	0	110.9	L311 L314 H315 V318 F380 S381 D386 Y387 V388 F481	L311-L384 HydrophobicContact CD2-CD2 3.61Å; L314-L384 HydrophobicContact CD2-CD1 4.19Å; L314-L384 HydrophobicContact CD2-CD2 3.63Å; L314-L384 HydrophobicContact CG-CD1 3.82Å; L314-L384 HydrophobicContact CG-CD2 4.05Å; H315-L384 HydrophobicContact CB-CB 4.09Å; V318-L384 HydrophobicContact CB-CD1 4.12Å; V318-L384 HydrophobicContact CG2-CD1 3.73Å; F380-L384 HydrophobicContact CD2-CD1 3.86Å; F380-L384 HydrophobicContact CD2-CG 4.02Å; F380-L384 HydrophobicContact CE1-CD1 4.39Å; F380-L384 HydrophobicContact CE2-CD1 3.7Å; F380-L384 HydrophobicContact CE2-CD2 4.15Å; F380-L384 HydrophobicContact CE2-CG 3.92Å; F380-L384 HydrophobicContact CG-CD1 4.28Å; F380-L384 HydrophobicContact CZ-CD1 3.99Å; F380-L384 WeakPolarHBondContact O-CG 3.48Å; F380-L384 PolarHBondContact O-N 2.95Å; S381-L384 PolarHBondContact O-N 3.09Å; L384-D386 PolarHBondContact O-N 3.49Å; L384-Y387 PolarHBondContact O-N 3.27Å; L384-V388 WeakPolarHBondContact O-CG2 3.31Å; L384-V388 PolarHBondContact O-N 3.35Å; L384-F481 HydrophobicContact CD2-CE1 3.82Å; L384-F481 HydrophobicContact CD2-CZ 4.19Å
385	G	91.7	Very high	92.6	Very high	4 Å²	4	18.8 Å²	18.8	4%	0.041	10%	0.1	C	C	.	.	H	α-helix	trans	-61	-32.6	178.1	0	0	0	0	0	112.2	H315 S381 R389	H315-G385 VanDerWaalsContact CD2-CA 3.45Å; H315-G385 WeakPolarHBondContact CD2-CA 3.34Å; H315-G385 PolarHBondContact CD2-N 3.48Å; H315-G385 WeakPolarHBondContact NE2-CA 3.34Å; S381-G385 PolarHBondContact O-N 2.66Å; G385-R389 WeakPolarHBondContact O-CG 3.16Å; G385-R389 PolarHBondContact O-N 3.45Å; G385-R389 PolarHBondContact O-NH1 2.76Å
386	D	90.4	Very high	92.5	Very high	8 Å²	8	19 Å²	19	4%	0.043	10%	0.104	C	C	.	.	H	α-helix	trans	-65.6	-49	173.7	-131	-0.7	0	0	0	113.6	R232 R236 E382 L383 L384 V388 R389 L390	R232-D386 WeakPolarHBondContact CD-OD2 3.28Å; R232-D386 IonicContact CZ-OD2 2.86Å; R232-D386 IonicContact NE-OD2 2.68Å; R232-D386 VanDerWaalsContact NH1-CG 3.27Å; R232-D386 IonicContact NH1-OD2 3.98Å; R232-D386 PolarHBondContact NH1-OD2 3.5Å; R236-D386 IonicContact CZ-OD2 3.95Å; R236-D386 IonicContact NH1-OD1 3.7Å; R236-D386 PolarHBondContact NH1-OD1 2.94Å; R236-D386 VanDerWaalsContact NH1-OD1 3.14Å; R236-D386 IonicContact NH1-OD2 2.73Å; R236-D386 PolarHBondContact NH1-OD2 2.91Å; R236-D386 VanDerWaalsContact NH2-CG 3.33Å; R236-D386 IonicContact NH2-OD2 3.71Å; R236-D386 PolarHBondContact NH2-OD2 2.91Å; E382-D386 WeakPolarHBondContact O-CB 3.28Å; E382-D386 PolarHBondContact O-N 3.12Å; E382-D386 VanDerWaalsContact O-N 3.09Å; L383-D386 WeakPolarHBondContact O-CB 3.38Å; L383-D386 PolarHBondContact O-N 2.87Å; L384-D386 PolarHBondContact O-N 3.49Å; D386-V388 VanDerWaalsContact C-N 3.3Å; D386-V388 PolarHBondContact O-N 3.24Å; D386-R389 VanDerWaalsContact CA-NH2 3.32Å; D386-R389 PolarHBondContact O-N 3.12Å; D386-R389 VanDerWaalsContact O-N 3.12Å; D386-R389 IonicContact OD1-CZ 2.66Å; D386-R389 IonicContact OD1-NE 2.97Å; D386-R389 IonicContact OD1-NH2 3.95Å; D386-R389 PolarHBondContact OD1-NH2 2.97Å; D386-L390 PolarHBondContact O-N 3.5Å
387	Y	94.1	Very high	92.6	Very high	3 Å²	3	19 Å²	19	1%	0.012	10%	0.104	C	C	.	.	H	α-helix	trans	-68.9	-31.4	-179.3	-90.2	-79.7	0	0	0	111.9	L383 L384 R389 L390 I391 F473 R477 D480 F481	L383-Y387 HydrophobicContact CD1-CD2 3.72Å; L383-Y387 HydrophobicContact CD1-CE2 3.61Å; L383-Y387 HydrophobicContact CG-CD2 4.11Å; L383-Y387 HydrophobicContact CG-CE2 4.44Å; L383-Y387 PolarHBondContact O-N 2.69Å; L384-Y387 PolarHBondContact O-N 3.27Å; Y387-R389 VanDerWaalsContact C-N 3.35Å; Y387-R389 PolarHBondContact O-N 3.32Å; Y387-L390 HydrophobicContact CD1-CD1 4.01Å; Y387-L390 HydrophobicContact CE1-CD1 4Å; Y387-L390 HydrophobicContact CG-CD1 4.33Å; Y387-L390 PolarHBondContact O-N 3.37Å; Y387-I391 WeakPolarHBondContact O-CB 3.36Å; Y387-I391 WeakPolarHBondContact O-CD1 3.37Å; Y387-I391 WeakPolarHBondContact O-CG1 3.42Å; Y387-I391 PolarHBondContact O-N 2.67Å; Y387-F473 HydrophobicContact CD1-CE2 4.29Å; Y387-F473 AromaticContact CD1-CZ 3.84Å; Y387-F473 HydrophobicContact CD1-CZ 3.84Å; Y387-F473 HydrophobicContact CE1-CE2 4.03Å; Y387-F473 AromaticContact CE1-CZ 3.92Å; Y387-F473 HydrophobicContact CE1-CZ 3.92Å; Y387-R477 HydrophobicContact CD1-CB 4.27Å; Y387-R477 HydrophobicContact CD1-CG 3.75Å; Y387-R477 HydrophobicContact CE1-CB 3.55Å; Y387-R477 HydrophobicContact CE1-CG 3.49Å; Y387-R477 VanDerWaalsContact CE1-CG 3.49Å; Y387-R477 VanDerWaalsContact OH-CA 3.32Å; Y387-R477 WeakPolarHBondContact OH-CA 3.43Å; Y387-D480 HydrophobicContact CE2-CB 3.99Å; Y387-D480 WeakPolarHBondContact OH-CB 3.36Å; Y387-D480 PolarHBondContact OH-OD2 3.48Å; Y387-F481 AromaticContact CD1-CE2 3.87Å; Y387-F481 HydrophobicContact CD1-CE2 3.87Å; Y387-F481 HydrophobicContact CD2-CD2 4.08Å; Y387-F481 AromaticContact CD2-CE2 3.38Å; Y387-F481 HydrophobicContact CD2-CE2 3.38Å; Y387-F481 AromaticContact CD2-CZ 3.95Å; Y387-F481 HydrophobicContact CD2-CZ 3.95Å; Y387-F481 HydrophobicContact CE1-CE2 4.3Å; Y387-F481 HydrophobicContact CE2-CD2 4.1Å; Y387-F481 AromaticContact CE2-CE2 3.86Å; Y387-F481 HydrophobicContact CE2-CE2 3.86Å; Y387-F481 HydrophobicContact CG-CD2 4.37Å; Y387-F481 AromaticContact CG-CE2 3.4Å; Y387-F481 HydrophobicContact CG-CE2 3.4Å; Y387-F481 AromaticContact CG-CZ 3.98Å; Y387-F481 HydrophobicContact CG-CZ 3.98Å
388	V	94	Very high	92.7	Very high	21 Å²	21	19.2 Å²	19.2	13%	0.127	10%	0.104	C	C	.	.	H	α-helix	trans	-56.7	-48	167.5	169.3	0	0	0	0	110.9	L311 K312 L384 D386 I391 G392	L311-V388 HydrophobicContact CB-CG2 3.81Å; K312-V388 HydrophobicContact CD-CG1 4.34Å; K312-V388 HydrophobicContact CG-CG1 3.68Å; K312-V388 HydrophobicContact CG-CG2 3.98Å; L384-V388 WeakPolarHBondContact O-CG2 3.31Å; L384-V388 PolarHBondContact O-N 3.35Å; D386-V388 VanDerWaalsContact C-N 3.3Å; D386-V388 PolarHBondContact O-N 3.24Å; V388-I391 PolarHBondContact O-N 2.97Å; V388-G392 PolarHBondContact O-N 3.28Å; V388-G392 VanDerWaalsContact O-N 3.12Å
389	R	91.8	Very high	92.9	Very high	64 Å²	64	17.9 Å²	17.9	24%	0.242	10%	0.103	C	C	.	.	H	α-helix	trans	-66.4	-40	178.3	-67.9	-177.4	-65.9	-91	1.5	112.3	P198 G385 D386 Y387 G392 A393	P198-R389 HydrophobicContact CB-CB 3.98Å; P198-R389 HydrophobicContact CG-CB 3.54Å; G385-R389 WeakPolarHBondContact O-CG 3.16Å; G385-R389 PolarHBondContact O-N 3.45Å; G385-R389 PolarHBondContact O-NH1 2.76Å; D386-R389 VanDerWaalsContact CA-NH2 3.32Å; D386-R389 PolarHBondContact O-N 3.12Å; D386-R389 VanDerWaalsContact O-N 3.12Å; D386-R389 IonicContact OD1-CZ 2.66Å; D386-R389 IonicContact OD1-NE 2.97Å; D386-R389 IonicContact OD1-NH2 3.95Å; D386-R389 PolarHBondContact OD1-NH2 2.97Å; Y387-R389 VanDerWaalsContact C-N 3.35Å; Y387-R389 PolarHBondContact O-N 3.32Å; R389-G392 WeakPolarHBondContact O-CA 3.2Å; R389-G392 PolarHBondContact O-N 3.18Å; R389-G392 VanDerWaalsContact O-N 3.15Å; R389-A393 PolarHBondContact O-N 3.33Å; R389-A393 VanDerWaalsContact O-N 3.08Å
390	L	93.8	Very high	93	Very high	6 Å²	6	18.6 Å²	18.6	3%	0.031	11%	0.105	C	C	.	.	H	α-helix	trans	-65	-40.4	177.9	-78.9	162.5	0	0	0	112.5	P198 R236 D386 Y387 G392 A393 V394 F473	P198-L390 VanDerWaalsContact CD-CD2 3.46Å; P198-L390 HydrophobicContact CG-CD2 4.35Å; P198-L390 HydrophobicContact CG-CG 4.29Å; R236-L390 VanDerWaalsContact CZ-CD1 3.49Å; D386-L390 PolarHBondContact O-N 3.5Å; Y387-L390 HydrophobicContact CD1-CD1 4.01Å; Y387-L390 HydrophobicContact CE1-CD1 4Å; Y387-L390 HydrophobicContact CG-CD1 4.33Å; Y387-L390 PolarHBondContact O-N 3.37Å; L390-G392 PolarHBondContact O-N 2.91Å; L390-A393 CarbonylContact O-C 3.56Å; L390-A393 WeakPolarHBondContact O-CA 3.32Å; L390-A393 VanDerWaalsContact O-CB 3.29Å; L390-A393 WeakPolarHBondContact O-CB 3.19Å; L390-A393 PolarHBondContact O-N 2.87Å; L390-V394 PolarHBondContact O-N 3.2Å; L390-F473 HydrophobicContact CB-CE2 3.67Å; L390-F473 HydrophobicContact CB-CZ 3.95Å; L390-F473 HydrophobicContact CD1-CE2 4.17Å; L390-F473 HydrophobicContact CD2-CE2 4.32Å; L390-F473 HydrophobicContact CG-CE2 4.29Å
391	I	95.6	Very high	93.1	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62.1	-36.5	172.9	-69.1	161.1	0	0	0	110.2	F304 L307 D308 L311 Y387 V388 A393 V394 K395 F473	F304-I391 HydrophobicContact CB-CG2 4.38Å; F304-I391 HydrophobicContact CD1-CG1 4.27Å; F304-I391 HydrophobicContact CD1-CG2 4.09Å; L307-I391 HydrophobicContact CB-CD1 4.48Å; L307-I391 HydrophobicContact CD2-CD1 3.55Å; L307-I391 HydrophobicContact CD2-CG1 4.2Å; L307-I391 HydrophobicContact CG-CD1 3.71Å; D308-I391 HydrophobicContact CB-CG2 3.79Å; L311-I391 HydrophobicContact CD1-CD1 3.33Å; Y387-I391 WeakPolarHBondContact O-CB 3.36Å; Y387-I391 WeakPolarHBondContact O-CD1 3.37Å; Y387-I391 WeakPolarHBondContact O-CG1 3.42Å; Y387-I391 PolarHBondContact O-N 2.67Å; V388-I391 PolarHBondContact O-N 2.97Å; I391-A393 VanDerWaalsContact C-N 3.28Å; I391-A393 PolarHBondContact O-N 2.82Å; I391-V394 WeakPolarHBondContact O-CB 3.38Å; I391-V394 PolarHBondContact O-N 3.35Å; I391-K395 HydrophobicContact CG2-CD 4.2Å; I391-K395 WeakPolarHBondContact O-CG 3.17Å; I391-K395 PolarHBondContact O-N 3.3Å; I391-F473 HydrophobicContact CG1-CE1 4.4Å; I391-F473 HydrophobicContact CG1-CZ 4.26Å
392	G	93.7	Very high	93	Very high	38 Å²	38	19.8 Å²	19.8	39%	0.392	11%	0.111	S	C	.	.	H	α-helix	trans	-55.2	-40.4	167.5	0	0	0	0	0	113.4	V388 R389 L390 G396	V388-G392 PolarHBondContact O-N 3.28Å; V388-G392 VanDerWaalsContact O-N 3.12Å; R389-G392 WeakPolarHBondContact O-CA 3.2Å; R389-G392 PolarHBondContact O-N 3.18Å; R389-G392 VanDerWaalsContact O-N 3.15Å; L390-G392 PolarHBondContact O-N 2.91Å; G392-G396 PolarHBondContact O-N 2.82Å
393	A	94.1	Very high	93.1	Very high	17 Å²	17	24.9 Å²	24.9	14%	0.14	13%	0.134	C	C	.	.	H	α-helix	trans	-69.2	-38.4	175.1	0	0	0	0	0	112.6	I195 R389 L390 I391 G396 V397	I195-A393 HydrophobicContact CG2-CB 4.13Å; R389-A393 PolarHBondContact O-N 3.33Å; R389-A393 VanDerWaalsContact O-N 3.08Å; L390-A393 CarbonylContact O-C 3.56Å; L390-A393 WeakPolarHBondContact O-CA 3.32Å; L390-A393 VanDerWaalsContact O-CB 3.29Å; L390-A393 WeakPolarHBondContact O-CB 3.19Å; L390-A393 PolarHBondContact O-N 2.87Å; I391-A393 VanDerWaalsContact C-N 3.28Å; I391-A393 PolarHBondContact O-N 2.82Å; A393-G396 WeakPolarHBondContact O-CA 3.45Å; A393-G396 PolarHBondContact O-N 3.36Å; A393-G396 VanDerWaalsContact O-N 3.12Å; A393-V397 PolarHBondContact O-N 3.46Å; A393-V397 VanDerWaalsContact O-N 3.13Å
394	V	96.4	Very high	93.2	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-60.1	-48	172.6	178.3	0	0	0	0	110.9	I195 F304 L390 I391 G396 V397 F398 V470 F473	I195-V394 HydrophobicContact CD1-CG2 3.85Å; I195-V394 HydrophobicContact CG1-CG2 4.38Å; I195-V394 HydrophobicContact CG2-CG2 4.43Å; F304-V394 HydrophobicContact CD1-CG1 4.13Å; F304-V394 HydrophobicContact CD2-CG1 3.8Å; F304-V394 HydrophobicContact CE1-CG1 4.08Å; F304-V394 HydrophobicContact CE1-CG2 4.38Å; F304-V394 HydrophobicContact CE2-CG1 3.76Å; F304-V394 HydrophobicContact CG-CG1 4.01Å; F304-V394 HydrophobicContact CZ-CG1 3.9Å; L390-V394 PolarHBondContact O-N 3.2Å; I391-V394 WeakPolarHBondContact O-CB 3.38Å; I391-V394 PolarHBondContact O-N 3.35Å; V394-G396 PolarHBondContact O-N 2.94Å; V394-V397 WeakPolarHBondContact O-CG2 2.94Å; V394-V397 PolarHBondContact O-N 3.46Å; V394-V397 VanDerWaalsContact O-N 3.11Å; V394-F398 HydrophobicContact CG1-CE2 3.91Å; V394-F398 HydrophobicContact CG1-CZ 4.11Å; V394-F398 PolarHBondContact O-N 3.31Å; V394-V470 HydrophobicContact CG1-CG2 4.29Å; V394-F473 HydrophobicContact CG2-CD1 3.98Å; V394-F473 HydrophobicContact CG2-CD2 4.29Å; V394-F473 HydrophobicContact CG2-CE1 4.05Å; V394-F473 HydrophobicContact CG2-CE2 4.37Å; V394-F473 HydrophobicContact CG2-CG 4.1Å; V394-F473 HydrophobicContact CG2-CZ 4.23Å
395	K	94.3	Very high	93.1	Very high	46 Å²	46	27.4 Å²	27.4	20%	0.2	15%	0.145	C	C	.	.	H	α-helix	trans	-59.9	-35.3	174.4	-68.3	172.3	60.6	164.8	0	111.4	E305 D308 I391 V397 F398 D399	E305-K395 WeakPolarHBondContact OE1-CE 3.04Å; E305-K395 IonicContact OE1-NZ 3.27Å; E305-K395 PolarHBondContact OE1-NZ 3.38Å; E305-K395 IonicContact OE2-NZ 2.72Å; E305-K395 PolarHBondContact OE2-NZ 2.98Å; D308-K395 IonicContact OD2-NZ 3.64Å; D308-K395 PolarHBondContact OD2-NZ 3.06Å; I391-K395 HydrophobicContact CG2-CD 4.2Å; I391-K395 WeakPolarHBondContact O-CG 3.17Å; I391-K395 PolarHBondContact O-N 3.3Å; K395-V397 PolarHBondContact O-N 3.09Å; K395-F398 PolarHBondContact O-N 3.33Å; K395-D399 PolarHBondContact O-N 3.13Å
396	G	91.4	Very high	93.1	Very high	17 Å²	17	28.9 Å²	28.9	18%	0.175	15%	0.151	C	C	.	.	H	α-helix	trans	-59.7	-38.1	174	0	0	0	0	0	114.2	G392 A393 V394 D399 H400	G392-G396 PolarHBondContact O-N 2.82Å; A393-G396 WeakPolarHBondContact O-CA 3.45Å; A393-G396 PolarHBondContact O-N 3.36Å; A393-G396 VanDerWaalsContact O-N 3.12Å; V394-G396 PolarHBondContact O-N 2.94Å; G396-D399 PolarHBondContact O-N 3.36Å; G396-H400 PolarHBondContact O-N 2.86Å; G396-H400 PolarHBondContact O-ND1 3.36Å
397	V	95.1	Very high	93.1	Very high	0 Å²	0	35 Å²	35	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-73.4	-35.1	176.1	-64.8	0	0	0	0	112.2	L190 Y194 I195 A393 V394 K395 D399 H400 R401 I466	L190-V397 HydrophobicContact CD1-CG1 3.66Å; Y194-V397 WeakPolarHBondContact O-CG1 3.48Å; I195-V397 HydrophobicContact CG1-CG1 4.37Å; I195-V397 HydrophobicContact CG1-CG2 4.2Å; A393-V397 PolarHBondContact O-N 3.46Å; A393-V397 VanDerWaalsContact O-N 3.13Å; V394-V397 WeakPolarHBondContact O-CG2 2.94Å; V394-V397 PolarHBondContact O-N 3.46Å; V394-V397 VanDerWaalsContact O-N 3.11Å; K395-V397 PolarHBondContact O-N 3.09Å; V397-D399 VanDerWaalsContact C-N 3.32Å; V397-D399 PolarHBondContact O-N 3.06Å; V397-H400 PolarHBondContact O-N 3.28Å; V397-H400 VanDerWaalsContact O-N 3.15Å; V397-R401 PolarHBondContact O-N 2.84Å; V397-I466 HydrophobicContact CB-CD1 4.13Å; V397-I466 HydrophobicContact CB-CG1 4.09Å; V397-I466 HydrophobicContact CG2-CD1 4.36Å; V397-I466 HydrophobicContact CG2-CG1 4.11Å; V397-I466 HydrophobicContact CG2-CG2 4.3Å; V397-I466 WeakPolarHBondContact O-CD1 3.4Å
398	F	94.1	Very high	93.1	Very high	14 Å²	14	36.6 Å²	36.6	6%	0.061	18%	0.183	C	C	.	.	H	α-helix	trans	-61.4	-41.8	171.5	-64	-34.9	0	0	0	111.8	F297 K300 F304 V394 K395 H400 R401 M402 I466 V470	F297-F398 HydrophobicContact CD1-CD1 4.01Å; F297-F398 AromaticContact CD1-CE1 3.89Å; F297-F398 HydrophobicContact CD1-CE1 3.89Å; F297-F398 HydrophobicContact CE1-CD1 4.14Å; F297-F398 HydrophobicContact CE1-CE1 4Å; K300-F398 HydrophobicContact CB-CZ 4.14Å; F304-F398 AromaticContact CD2-CE2 3.77Å; F304-F398 HydrophobicContact CD2-CE2 3.77Å; F304-F398 HydrophobicContact CD2-CZ 4.03Å; F304-F398 HydrophobicContact CE2-CE2 4.47Å; F304-F398 HydrophobicContact CE2-CZ 4.32Å; F304-F398 HydrophobicContact CG-CE2 4.49Å; V394-F398 HydrophobicContact CG1-CE2 3.91Å; V394-F398 HydrophobicContact CG1-CZ 4.11Å; V394-F398 PolarHBondContact O-N 3.31Å; K395-F398 PolarHBondContact O-N 3.33Å; F398-H400 VanDerWaalsContact C-N 3.26Å; F398-H400 PolarHBondContact O-N 2.9Å; F398-R401 WeakPolarHBondContact O-CB 3.46Å; F398-R401 PolarHBondContact O-N 2.87Å; F398-R401 VanDerWaalsContact O-N 3.16Å; F398-M402 PolarHBondContact O-N 3.38Å; F398-I466 HydrophobicContact CD1-CG2 3.85Å; F398-I466 HydrophobicContact CE1-CG2 3.48Å; F398-I466 VanDerWaalsContact CE1-CG2 3.48Å; F398-V470 HydrophobicContact CE1-CG2 4.22Å; F398-V470 HydrophobicContact CZ-CG2 4.08Å
399	D	91.7	Very high	92.9	Very high	52 Å²	52	37.8 Å²	37.8	28%	0.278	19%	0.187	S	C	.	.	H	α-helix	trans	-61.2	-33.7	174.4	-78.1	-11.5	0	0	0	112.5	K285 K395 G396 V397 M402 K403	K285-D399 WeakPolarHBondContact CE-OD1 3.42Å; K285-D399 IonicContact NZ-OD1 3.35Å; K285-D399 PolarHBondContact NZ-OD1 3.15Å; K285-D399 IonicContact NZ-OD2 2.69Å; K285-D399 PolarHBondContact NZ-OD2 3.2Å; K395-D399 PolarHBondContact O-N 3.13Å; G396-D399 PolarHBondContact O-N 3.36Å; V397-D399 VanDerWaalsContact C-N 3.32Å; V397-D399 PolarHBondContact O-N 3.06Å; D399-M402 WeakPolarHBondContact O-CB 3.27Å; D399-K403 WeakPolarHBondContact O-CG 3.38Å; D399-K403 PolarHBondContact O-N 3.5Å; D399-K403 VanDerWaalsContact O-N 3.12Å
400	H	92.5	Very high	92.9	Very high	47 Å²	47	38.3 Å²	38.3	22%	0.218	20%	0.195	C	C	.	.	H	α-helix	trans	-71.9	-40.1	174.2	-77.3	74.7	0	0	0	112.1	L190 G396 V397 F398 M402 K403 T404 I462	L190-H400 WeakPolarHBondContact CD2-CE1 3.46Å; L190-H400 VanDerWaalsContact CG-CE1 3.47Å; L190-H400 WeakPolarHBondContact CG-CE1 3.45Å; G396-H400 PolarHBondContact O-N 2.86Å; G396-H400 PolarHBondContact O-ND1 3.36Å; V397-H400 PolarHBondContact O-N 3.28Å; V397-H400 VanDerWaalsContact O-N 3.15Å; F398-H400 VanDerWaalsContact C-N 3.26Å; F398-H400 PolarHBondContact O-N 2.9Å; H400-M402 VanDerWaalsContact C-N 3.3Å; H400-M402 PolarHBondContact O-N 3Å; H400-K403 PolarHBondContact O-N 3.48Å; H400-K403 VanDerWaalsContact O-N 3.16Å; H400-T404 PolarHBondContact O-N 3.36Å; H400-T404 PolarHBondContact O-OG1 3.37Å; H400-T404 VanDerWaalsContact O-OG1 3.11Å; H400-I462 HydrophobicContact CB-CD1 4.04Å
401	R	93.8	Very high	92.8	Very high	9 Å²	9	39 Å²	39	3%	0.034	20%	0.201	C	C	.	.	H	α-helix	trans	-57.9	-44.2	172.8	176.7	175.1	173.3	-88.1	8.3	111.6	E292 V397 F398 K403 T404 W405 F459 I462 S463 I466	E292-R401 IonicContact OE1-CZ 3.86Å; E292-R401 IonicContact OE1-NH1 3.34Å; E292-R401 PolarHBondContact OE1-NH1 3.44Å; E292-R401 IonicContact OE1-NH2 2.92Å; E292-R401 PolarHBondContact OE1-NH2 2.89Å; E292-R401 IonicContact OE2-CZ 2.63Å; E292-R401 IonicContact OE2-NH1 2.69Å; E292-R401 PolarHBondContact OE2-NH1 2.84Å; E292-R401 IonicContact OE2-NH2 3.57Å; V397-R401 PolarHBondContact O-N 2.84Å; F398-R401 WeakPolarHBondContact O-CB 3.46Å; F398-R401 PolarHBondContact O-N 2.87Å; F398-R401 VanDerWaalsContact O-N 3.16Å; R401-K403 PolarHBondContact O-N 3.31Å; R401-T404 PolarHBondContact O-N 3.2Å; R401-W405 PolarHBondContact O-N 3.44Å; R401-F459 HydrophobicContact CG-CD2 4.14Å; R401-F459 HydrophobicContact CG-CE2 3.59Å; R401-I462 HydrophobicContact CB-CD1 4.28Å; R401-I462 HydrophobicContact CB-CG1 4.47Å; R401-I462 HydrophobicContact CB-CG2 4.35Å; R401-I462 HydrophobicContact CG-CG2 4.25Å; R401-S463 WeakPolarHBondContact CD-OG 3.47Å; R401-S463 PolarHBondContact NE-OG 3.35Å; R401-I466 HydrophobicContact CB-CD1 3.68Å; R401-I466 HydrophobicContact CG-CD1 4.45Å
402	M	90.6	Very high	92.7	Very high	49 Å²	49	42.8 Å²	42.8	24%	0.241	22%	0.218	C	C	.	.	H	α-helix	trans	-57.2	-45.8	174.1	-177.8	71.9	170.5	0	0	112.1	I288 M290 F398 D399 H400 W405 Q406	I288-M402 HydrophobicContact CG2-CE 4.26Å; I288-M402 VanDerWaalsContact O-CE 3.27Å; I288-M402 WeakPolarHBondContact O-CE 3.46Å; M290-M402 HydrophobicContact CB-CE 3.33Å; M290-M402 HydrophobicContact CB-SD 3.24Å; M290-M402 WeakPolarHBondContact CB-SD 3.47Å; M290-M402 HydrophobicContact CG-SD 3.96Å; M290-M402 HydrophobicContact SD-SD 3.48Å; F398-M402 PolarHBondContact O-N 3.38Å; D399-M402 WeakPolarHBondContact O-CB 3.27Å; H400-M402 VanDerWaalsContact C-N 3.3Å; H400-M402 PolarHBondContact O-N 3Å; M402-W405 WeakPolarHBondContact O-CB 3.49Å; M402-W405 PolarHBondContact O-N 3Å; M402-Q406 WeakPolarHBondContact O-CB 3.04Å; M402-Q406 PolarHBondContact O-N 3.48Å
403	K	91.8	Very high	92.6	Very high	115 Å²	115	45.1 Å²	45.1	50%	0.5	22%	0.22	S	C	.	.	H	α-helix	trans	-64.5	-40	177.4	-72.2	173.4	-178	-175.3	0	112.4	D399 H400 R401 Q406 K407	D399-K403 WeakPolarHBondContact O-CG 3.38Å; D399-K403 PolarHBondContact O-N 3.5Å; D399-K403 VanDerWaalsContact O-N 3.12Å; H400-K403 PolarHBondContact O-N 3.48Å; H400-K403 VanDerWaalsContact O-N 3.16Å; R401-K403 PolarHBondContact O-N 3.31Å; K403-Q406 PolarHBondContact O-N 3.33Å; K403-K407 PolarHBondContact O-N 3Å
404	T	92.5	Very high	92.6	Very high	27 Å²	27	48.3 Å²	48.3	17%	0.166	23%	0.234	C	C	.	.	H	α-helix	trans	-64.4	-43.5	176	-58.3	0	0	0	0	111.1	H400 R401 K407 W408 D458 F459 I462	H400-T404 PolarHBondContact O-N 3.36Å; H400-T404 PolarHBondContact O-OG1 3.37Å; H400-T404 VanDerWaalsContact O-OG1 3.11Å; R401-T404 PolarHBondContact O-N 3.2Å; T404-K407 PolarHBondContact O-N 2.94Å; T404-W408 PolarHBondContact O-N 2.83Å; T404-W408 VanDerWaalsContact O-N 3.09Å; T404-D458 HydrophobicContact CG2-CB 3.87Å; T404-F459 HydrophobicContact CG2-CB 4.13Å; T404-I462 HydrophobicContact CG2-CG2 4.28Å
405	W	92.3	Very high	92.4	Very high	39 Å²	39	48.8 Å²	48.8	15%	0.148	24%	0.237	C	C	.	.	H	α-helix	trans	-59.1	-46.8	173.1	179.4	81.9	0	0	0	112	I288 M290 R401 M402 K407 W408 Q409 F459	I288-W405 HydrophobicContact CG2-CZ3 4.39Å; M290-W405 HydrophobicContact CB-CD2 4.21Å; M290-W405 HydrophobicContact CB-CE3 3.72Å; M290-W405 HydrophobicContact CB-CH2 3.88Å; M290-W405 HydrophobicContact CB-CZ2 4.32Å; M290-W405 HydrophobicContact CB-CZ3 3.55Å; M290-W405 HydrophobicContact CE-CB 4.25Å; M290-W405 HydrophobicContact CE-CD2 4.13Å; M290-W405 HydrophobicContact CE-CG 3.77Å; M290-W405 HydrophobicContact CG-CD2 3.65Å; M290-W405 HydrophobicContact CG-CE3 3.71Å; M290-W405 HydrophobicContact CG-CG 4.29Å; M290-W405 HydrophobicContact CG-CH2 3.98Å; M290-W405 HydrophobicContact CG-CZ2 3.89Å; M290-W405 HydrophobicContact CG-CZ3 3.88Å; M290-W405 HydrophobicContact SD-CB 3.97Å; M290-W405 HydrophobicContact SD-CD2 3.62Å; M290-W405 HydrophobicContact SD-CE3 3.88Å; M290-W405 HydrophobicContact SD-CG 3.67Å; R401-W405 PolarHBondContact O-N 3.44Å; M402-W405 WeakPolarHBondContact O-CB 3.49Å; M402-W405 PolarHBondContact O-N 3Å; W405-K407 VanDerWaalsContact C-N 3.34Å; W405-K407 PolarHBondContact O-N 2.95Å; W405-W408 WeakPolarHBondContact O-CB 3.46Å; W405-W408 PolarHBondContact O-N 3.33Å; W405-W408 VanDerWaalsContact O-N 3.12Å; W405-Q409 HydrophobicContact CD2-CG 3.89Å; W405-Q409 VanDerWaalsContact CE2-CG 3.48Å; W405-Q409 HydrophobicContact CE3-CG 4.29Å; W405-Q409 HydrophobicContact CG-CG 4.46Å; W405-Q409 HydrophobicContact CH2-CG 3.98Å; W405-Q409 HydrophobicContact CZ2-CG 3.56Å; W405-Q409 HydrophobicContact CZ3-CG 4.33Å; W405-Q409 WeakPolarHBondContact O-CG 3.27Å; W405-Q409 PolarHBondContact O-N 3.05Å; W405-F459 HydrophobicContact CB-CD2 3.71Å; W405-F459 HydrophobicContact CB-CE2 3.55Å; W405-F459 HydrophobicContact CB-CZ 4.31Å; W405-F459 AromaticContact CD1-CE2 3.92Å; W405-F459 AromaticContact CD1-CZ 3.82Å; W405-F459 HydrophobicContact CG-CD2 4.47Å; W405-F459 HydrophobicContact CG-CE2 4.09Å; W405-F459 HydrophobicContact CG-CZ 4.39Å
406	Q	90.3	Very high	92.4	Very high	35 Å²	35	52 Å²	52	16%	0.164	25%	0.252	C	S	.	.	H	α-helix	trans	-59.2	-46.2	179.5	-174	58.3	37	0	0	111.5	I288 M402 K403 W408 Q409 D410	I288-Q406 HydrophobicContact CD1-CG 4.28Å; M402-Q406 WeakPolarHBondContact O-CB 3.04Å; M402-Q406 PolarHBondContact O-N 3.48Å; K403-Q406 PolarHBondContact O-N 3.33Å; Q406-W408 VanDerWaalsContact C-N 3.27Å; Q406-W408 PolarHBondContact O-N 3.17Å; Q406-Q409 PolarHBondContact O-N 3.15Å; Q406-D410 PolarHBondContact NE2-OD1 3.29Å; Q406-D410 WeakPolarHBondContact O-CB 3.5Å; Q406-D410 PolarHBondContact O-N 3.49Å
407	K	91.6	Very high	92.5	Very high	136 Å²	136	58 Å²	58	59%	0.591	27%	0.273	S	S	*	.	H	α-helix	trans	-59.6	-38.7	177.1	-175.5	-174.7	175.4	-167.3	0	112.2	K403 T404 W405 S411	K403-K407 PolarHBondContact O-N 3Å; T404-K407 PolarHBondContact O-N 2.94Å; W405-K407 VanDerWaalsContact C-N 3.34Å; W405-K407 PolarHBondContact O-N 2.95Å; K407-S411 PolarHBondContact O-N 3.43Å; K407-S411 PolarHBondContact O-OG 2.91Å
408	W	93.3	Very high	92.3	Very high	36 Å²	36	61 Å²	61	14%	0.136	29%	0.287	C	S	.	.	H	α-helix	trans	-65.6	-48.3	175.7	172.3	36.9	0	0	0	111.5	T404 W405 Q406 D410 S411 Q412 V452 E456 F459	T404-W408 PolarHBondContact O-N 2.83Å; T404-W408 VanDerWaalsContact O-N 3.09Å; W405-W408 WeakPolarHBondContact O-CB 3.46Å; W405-W408 PolarHBondContact O-N 3.33Å; W405-W408 VanDerWaalsContact O-N 3.12Å; Q406-W408 VanDerWaalsContact C-N 3.27Å; Q406-W408 PolarHBondContact O-N 3.17Å; W408-D410 PolarHBondContact O-N 2.93Å; W408-S411 WeakPolarHBondContact O-CB 3.39Å; W408-S411 PolarHBondContact O-N 3.18Å; W408-Q412 PolarHBondContact O-N 2.86Å; W408-V452 PolarHBondContact NE1-O 2.95Å; W408-E456 HydrophobicContact CD2-CB 4.37Å; W408-E456 HydrophobicContact CH2-CG 4.13Å; W408-E456 HydrophobicContact CZ2-CB 3.84Å; W408-E456 HydrophobicContact CZ2-CG 3.67Å; W408-F459 HydrophobicContact CE3-CB 4.24Å; W408-F459 AromaticContact CE3-CD1 4Å; W408-F459 HydrophobicContact CE3-CD1 4Å; W408-F459 HydrophobicContact CE3-CG 4.17Å; W408-F459 AromaticContact CZ3-CD1 3.74Å; W408-F459 HydrophobicContact CZ3-CD1 3.74Å; W408-F459 HydrophobicContact CZ3-CE1 4.18Å; W408-F459 HydrophobicContact CZ3-CG 4.37Å
409	Q	91.4	Very high	92.1	Very high	46 Å²	46	66.2 Å²	66.2	22%	0.215	31%	0.306	C	S	.	.	H	α-helix	trans	-62.9	-41.2	178.1	-70.5	-60.3	-56.4	0	0	112.7	W405 Q406 S411 Q412 M413	W405-Q409 HydrophobicContact CD2-CG 3.89Å; W405-Q409 VanDerWaalsContact CE2-CG 3.48Å; W405-Q409 HydrophobicContact CE3-CG 4.29Å; W405-Q409 HydrophobicContact CG-CG 4.46Å; W405-Q409 HydrophobicContact CH2-CG 3.98Å; W405-Q409 HydrophobicContact CZ2-CG 3.56Å; W405-Q409 HydrophobicContact CZ3-CG 4.33Å; W405-Q409 WeakPolarHBondContact O-CG 3.27Å; W405-Q409 PolarHBondContact O-N 3.05Å; Q406-Q409 PolarHBondContact O-N 3.15Å; Q409-S411 VanDerWaalsContact C-N 3.3Å; Q409-S411 PolarHBondContact O-N 3.14Å; Q409-Q412 VanDerWaalsContact NE2-OE1 3.09Å; Q409-Q412 WeakPolarHBondContact O-CB 3.25Å; Q409-Q412 PolarHBondContact O-N 3.49Å; Q409-Q412 VanDerWaalsContact O-N 3.15Å; Q409-M413 WeakPolarHBondContact O-CG 3.33Å; Q409-M413 PolarHBondContact O-N 3.39Å
410	D	90.8	Very high	92	Very high	75 Å²	75	68 Å²	68	40%	0.401	31%	0.313	S	S	.	.	H	α-helix	trans	-60.4	-42.1	175.5	-69.9	-22.7	0	0	0	111.5	Q406 W408 Q412 M413 L414	Q406-D410 PolarHBondContact NE2-OD1 3.29Å; Q406-D410 WeakPolarHBondContact O-CB 3.5Å; Q406-D410 PolarHBondContact O-N 3.49Å; W408-D410 PolarHBondContact O-N 2.93Å; D410-Q412 VanDerWaalsContact C-N 3.34Å; D410-M413 VanDerWaalsContact OD1-CE 3.32Å; D410-M413 WeakPolarHBondContact OD1-CE 3.39Å; D410-L414 WeakPolarHBondContact O-CB 3.25Å; D410-L414 PolarHBondContact O-N 2.89Å
411	S	92.6	Very high	91.7	Very high	22 Å²	22	67.6 Å²	67.6	15%	0.154	32%	0.318	C	S	.	.	H	α-helix	trans	-64.8	-39.7	175.5	-55.7	0	0	0	0	111.3	K407 W408 Q409 L414 L415 V452	K407-S411 PolarHBondContact O-N 3.43Å; K407-S411 PolarHBondContact O-OG 2.91Å; W408-S411 WeakPolarHBondContact O-CB 3.39Å; W408-S411 PolarHBondContact O-N 3.18Å; Q409-S411 VanDerWaalsContact C-N 3.3Å; Q409-S411 PolarHBondContact O-N 3.14Å; S411-L414 PolarHBondContact O-N 2.99Å; S411-L415 WeakPolarHBondContact O-CB 3.5Å; S411-L415 PolarHBondContact O-N 3.02Å; S411-V452 VanDerWaalsContact C-CG2 3.49Å
412	Q	92.8	Very high	91.2	Very high	78 Å²	78	68.8 Å²	68.8	36%	0.364	32%	0.323	S	S	.	.	H	α-helix	trans	-67	-43.5	178.6	-172.3	171.5	39.8	0	0	112	W408 Q409 D410 L415 Q416 V452	W408-Q412 PolarHBondContact O-N 2.86Å; Q409-Q412 VanDerWaalsContact NE2-OE1 3.09Å; Q409-Q412 WeakPolarHBondContact O-CB 3.25Å; Q409-Q412 PolarHBondContact O-N 3.49Å; Q409-Q412 VanDerWaalsContact O-N 3.15Å; D410-Q412 VanDerWaalsContact C-N 3.34Å; Q412-L415 PolarHBondContact O-N 3.44Å; Q412-Q416 PolarHBondContact O-N 3.37Å; Q412-V452 HydrophobicContact CB-CG2 4.26Å
413	M	92.4	Very high	91	Very high	87 Å²	87	68.3 Å²	68.3	43%	0.429	33%	0.327	S	S	.	.	H	α-helix	trans	-63.9	-40	174.7	-72.8	-171.4	-71.4	0	0	111.9	Q409 D410 Q416 K417	Q409-M413 WeakPolarHBondContact O-CG 3.33Å; Q409-M413 PolarHBondContact O-N 3.39Å; D410-M413 VanDerWaalsContact OD1-CE 3.32Å; D410-M413 WeakPolarHBondContact OD1-CE 3.39Å; M413-Q416 PolarHBondContact O-N 2.69Å; M413-K417 WeakPolarHBondContact O-CG 3.38Å; M413-K417 PolarHBondContact O-N 2.95Å
414	L	92.4	Very high	90.7	Very high	84 Å²	84	69.5 Å²	69.5	44%	0.44	33%	0.332	S	S	.	.	H	α-helix	trans	-65.4	-43.1	177.4	-176.7	58.3	0	0	0	111.4	D410 S411 Q416 K417 K418 L448	D410-L414 WeakPolarHBondContact O-CB 3.25Å; D410-L414 PolarHBondContact O-N 2.89Å; S411-L414 PolarHBondContact O-N 2.99Å; L414-Q416 VanDerWaalsContact C-N 3.34Å; L414-Q416 PolarHBondContact O-N 3.41Å; L414-K417 PolarHBondContact O-N 2.67Å; L414-K418 WeakPolarHBondContact O-CG 3.25Å; L414-K418 PolarHBondContact O-N 3.27Å; L414-L448 HydrophobicContact CB-CD2 4.46Å; L414-L448 HydrophobicContact CD2-CD1 4.42Å; L414-L448 HydrophobicContact CD2-CD2 3.63Å; L414-L448 HydrophobicContact CG-CD1 4.02Å; L414-L448 HydrophobicContact CG-CD2 3.96Å
415	L	93.6	Very high	90	Very high	11 Å²	11	70.9 Å²	70.9	6%	0.058	34%	0.338	C	S	.	.	H	α-helix	trans	-58.3	-45.9	173.2	175.9	62.1	0	0	0	111.4	S411 Q412 K417 K418 R419 I445 L448 E449 V452	S411-L415 WeakPolarHBondContact O-CB 3.5Å; S411-L415 PolarHBondContact O-N 3.02Å; Q412-L415 PolarHBondContact O-N 3.44Å; L415-K417 PolarHBondContact O-N 3.15Å; L415-K418 PolarHBondContact O-N 3.11Å; L415-R419 HydrophobicContact CD1-CG 4.31Å; L415-R419 WeakPolarHBondContact O-CG 3.48Å; L415-R419 PolarHBondContact O-N 2.72Å; L415-I445 HydrophobicContact CD1-CG2 3.98Å; L415-L448 HydrophobicContact CB-CB 4.19Å; L415-L448 HydrophobicContact CD1-CB 3.91Å; L415-E449 HydrophobicContact CD1-CG 3.77Å; L415-E449 HydrophobicContact CD2-CG 3.77Å; L415-E449 HydrophobicContact CG-CG 4.44Å; L415-V452 HydrophobicContact CB-CG2 4.26Å; L415-V452 HydrophobicContact CD2-CG2 3.99Å
416	Q	93.3	Very high	89.1	Confident	113 Å²	113	73.9 Å²	73.9	53%	0.528	35%	0.354	S	S	.	.	H	α-helix	trans	-60.1	-46.6	177.9	-176.4	175.5	-9.4	0	0	111.7	Q412 M413 L414 K418 R419 E420	Q412-Q416 PolarHBondContact O-N 3.37Å; M413-Q416 PolarHBondContact O-N 2.69Å; L414-Q416 VanDerWaalsContact C-N 3.34Å; L414-Q416 PolarHBondContact O-N 3.41Å; Q416-K418 VanDerWaalsContact C-N 3.3Å; Q416-K418 PolarHBondContact O-N 3.46Å; Q416-R419 PolarHBondContact O-N 3.23Å; Q416-E420 PolarHBondContact NE2-OE1 3.33Å; Q416-E420 WeakPolarHBondContact O-CG 3.18Å; Q416-E420 PolarHBondContact O-N 3.49Å
417	K	93.1	Very high	88.4	Confident	142 Å²	142	80.7 Å²	80.7	62%	0.617	38%	0.384	S	S	*	.	H	α-helix	trans	-60.2	-38.5	176.2	-73.9	176.6	-179.5	175.4	0	112.5	M413 L414 L415 A421	M413-K417 WeakPolarHBondContact O-CG 3.38Å; M413-K417 PolarHBondContact O-N 2.95Å; L414-K417 PolarHBondContact O-N 2.67Å; L415-K417 PolarHBondContact O-N 3.15Å; K417-A421 WeakPolarHBondContact O-CB 3.25Å; K417-A421 PolarHBondContact O-N 3.05Å
418	K	90.8	Very high	87.3	Confident	65 Å²	65	77.7 Å²	77.7	28%	0.283	38%	0.377	S	S	.	.	H	α-helix	trans	-69.1	-42.5	177.5	-75.2	-74	-174.9	169.1	0	112.2	L414 L415 Q416 E420 A421 E422 E444 I445 L448	L414-K418 WeakPolarHBondContact O-CG 3.25Å; L414-K418 PolarHBondContact O-N 3.27Å; L415-K418 PolarHBondContact O-N 3.11Å; Q416-K418 VanDerWaalsContact C-N 3.3Å; Q416-K418 PolarHBondContact O-N 3.46Å; K418-E420 VanDerWaalsContact C-N 3.34Å; K418-E420 PolarHBondContact O-N 2.98Å; K418-A421 WeakPolarHBondContact O-CB 3.21Å; K418-A421 PolarHBondContact O-N 3.48Å; K418-A421 VanDerWaalsContact O-N 3.16Å; K418-E422 PolarHBondContact O-N 3.19Å; K418-E444 VanDerWaalsContact CE-OE2 3.3Å; K418-E444 WeakPolarHBondContact CE-OE2 3.46Å; K418-E444 IonicContact NZ-OE1 2.67Å; K418-E444 IonicContact NZ-OE2 2.94Å; K418-E444 PolarHBondContact NZ-OE2 3.43Å; K418-I445 HydrophobicContact CB-CG1 4.13Å; K418-L448 HydrophobicContact CB-CD1 4.16Å; K418-L448 HydrophobicContact CG-CD1 3.69Å
419	R	90.4	Very high	85.7	Confident	123 Å²	123	83.7 Å²	83.7	46%	0.464	41%	0.411	S	S	.	.	H	α-helix	trans	-60.5	-40.6	172.6	-73.5	177.7	172.9	175.8	-3	112.4	L415 Q416 E422 A423 I445 E449	L415-R419 HydrophobicContact CD1-CG 4.31Å; L415-R419 WeakPolarHBondContact O-CG 3.48Å; L415-R419 PolarHBondContact O-N 2.72Å; Q416-R419 PolarHBondContact O-N 3.23Å; R419-E422 PolarHBondContact O-N 3.32Å; R419-A423 WeakPolarHBondContact O-CB 3.49Å; R419-A423 PolarHBondContact O-N 3Å; R419-I445 HydrophobicContact CG-CD1 4.18Å; R419-E449 IonicContact CZ-OE1 3.57Å; R419-E449 IonicContact NE-OE1 3.2Å; R419-E449 IonicContact NH2-OE1 2.67Å; R419-E449 PolarHBondContact NH2-OE1 3.43Å
420	E	89.7	Confident	84.5	Confident	89 Å²	89	88.7 Å²	88.7	42%	0.416	43%	0.433	S	S	.	.	H	α-helix	trans	-64.8	-38	174.4	-72.9	174.3	-163.3	0	0	112.6	Q416 K418 K424	Q416-E420 PolarHBondContact NE2-OE1 3.33Å; Q416-E420 WeakPolarHBondContact O-CG 3.18Å; Q416-E420 PolarHBondContact O-N 3.49Å; K418-E420 VanDerWaalsContact C-N 3.34Å; K418-E420 PolarHBondContact O-N 2.98Å; E420-K424 VanDerWaalsContact O-CG 3.31Å; E420-K424 WeakPolarHBondContact O-CG 3.37Å; E420-K424 PolarHBondContact O-N 2.88Å; E420-K424 VanDerWaalsContact O-N 3.12Å
421	A	86.2	Confident	83.1	Confident	39 Å²	39	90.1 Å²	90.1	32%	0.322	45%	0.446	S	S	.	.	H	α-helix	trans	-67.3	-41.9	175.5	0	0	0	0	0	111.8	K417 K418 K424 L425	K417-A421 WeakPolarHBondContact O-CB 3.25Å; K417-A421 PolarHBondContact O-N 3.05Å; K418-A421 WeakPolarHBondContact O-CB 3.21Å; K418-A421 PolarHBondContact O-N 3.48Å; K418-A421 VanDerWaalsContact O-N 3.16Å; A421-K424 PolarHBondContact O-N 2.94Å; A421-L425 WeakPolarHBondContact O-CG 3.29Å; A421-L425 PolarHBondContact O-N 3.27Å
422	E	84.6	Confident	81.6	Confident	33 Å²	33	96.1 Å²	96.1	15%	0.154	48%	0.476	C	S	.	.	H	α-helix	trans	-58.4	-49.6	173.6	-166.9	-160.6	171.3	0	0	110.8	K418 R419 K424 L425 Q426 I441 I445	K418-E422 PolarHBondContact O-N 3.19Å; R419-E422 PolarHBondContact O-N 3.32Å; E422-K424 VanDerWaalsContact C-N 3.32Å; E422-K424 PolarHBondContact O-N 3.47Å; E422-L425 PolarHBondContact O-N 3.05Å; E422-L425 VanDerWaalsContact O-N 3.08Å; E422-Q426 WeakPolarHBondContact O-CG 3.44Å; E422-Q426 PolarHBondContact O-N 2.98Å; E422-Q426 PolarHBondContact OE1-NE2 3.44Å; E422-I441 HydrophobicContact CB-CG2 3.78Å; E422-I441 HydrophobicContact CG-CG2 3.92Å; E422-I445 HydrophobicContact CB-CD1 4.01Å; E422-I445 HydrophobicContact CG-CD1 4.35Å; E422-I445 WeakPolarHBondContact OE2-CD1 3.19Å
423	A	85.8	Confident	80.1	Confident	39 Å²	39	101.8 Å²	101.8	32%	0.322	50%	0.5	S	S	.	.	H	α-helix	trans	-56.1	-46	178.6	0	0	0	0	0	111.5	R419 L425 Q426 F427	R419-A423 WeakPolarHBondContact O-CB 3.49Å; R419-A423 PolarHBondContact O-N 3Å; A423-L425 VanDerWaalsContact C-N 3.33Å; A423-L425 PolarHBondContact O-N 3.42Å; A423-Q426 PolarHBondContact O-N 2.92Å; A423-F427 WeakPolarHBondContact O-CD2 3.47Å; A423-F427 PolarHBondContact O-N 2.95Å
424	K	85.1	Confident	78.9	Confident	140 Å²	140	98.7 Å²	98.7	61%	0.609	49%	0.485	S	S	*	.	H	α-helix	trans	-61.3	-39	176.7	-72	168.5	-175.4	169.8	0	112.8	E420 A421 E422 F427 T428	E420-K424 VanDerWaalsContact O-CG 3.31Å; E420-K424 WeakPolarHBondContact O-CG 3.37Å; E420-K424 PolarHBondContact O-N 2.88Å; E420-K424 VanDerWaalsContact O-N 3.12Å; A421-K424 PolarHBondContact O-N 2.94Å; E422-K424 VanDerWaalsContact C-N 3.32Å; E422-K424 PolarHBondContact O-N 3.47Å; K424-F427 PolarHBondContact O-N 3.4Å; K424-T428 PolarHBondContact O-N 3.25Å; K424-T428 PolarHBondContact O-OG1 3.04Å
425	L	78.6	Confident	78.2	Confident	56 Å²	56	99.4 Å²	99.4	29%	0.293	49%	0.486	S	S	.	.	H	α-helix	trans	-70.7	-32.8	177.2	-73.8	167.8	0	0	0	112.4	A421 E422 A423 F427 T428 L434 I441	A421-L425 WeakPolarHBondContact O-CG 3.29Å; A421-L425 PolarHBondContact O-N 3.27Å; E422-L425 PolarHBondContact O-N 3.05Å; E422-L425 VanDerWaalsContact O-N 3.08Å; A423-L425 VanDerWaalsContact C-N 3.33Å; A423-L425 PolarHBondContact O-N 3.42Å; L425-F427 VanDerWaalsContact C-N 3.29Å; L425-F427 PolarHBondContact O-N 3.2Å; L425-T428 PolarHBondContact O-N 3.49Å; L425-T428 VanDerWaalsContact O-N 3.15Å; L425-L434 HydrophobicContact CD2-CD1 4.28Å; L425-I441 HydrophobicContact CD1-CD1 3.11Å
426	Q	73.4	Confident	77.4	Confident	103 Å²	103	105.2 Å²	105.2	48%	0.481	51%	0.513	S	S	.	.	H	α-helix	trans	-64.1	-33	173.2	-69.4	-177.9	7.4	0	0	112.3	E422 A423 T428	E422-Q426 WeakPolarHBondContact O-CG 3.44Å; E422-Q426 PolarHBondContact O-N 2.98Å; E422-Q426 PolarHBondContact OE1-NE2 3.44Å; A423-Q426 PolarHBondContact O-N 2.92Å; Q426-T428 VanDerWaalsContact C-N 3.3Å; Q426-T428 PolarHBondContact O-N 3.27Å
427	F	74.6	Confident	76.8	Confident	178 Å²	178	101.4 Å²	101.4	78%	0.781	50%	0.501	S	S	*	.	T	Hydrogen-bonded Turn	trans	-75.6	-12.1	174.2	-74	-71.7	0	0	0	114.3	A423 K424 L425 N429	A423-F427 WeakPolarHBondContact O-CD2 3.47Å; A423-F427 PolarHBondContact O-N 2.95Å; K424-F427 PolarHBondContact O-N 3.4Å; L425-F427 VanDerWaalsContact C-N 3.29Å; L425-F427 PolarHBondContact O-N 3.2Å; F427-N429 PolarHBondContact O-N 2.94Å
428	T	69	Low	76	Confident	73 Å²	73	97 Å²	97	45%	0.448	48%	0.481	S	S	.	.	S	Bend	trans	-94.3	98.5	-177.9	-52	0	0	0	0	110.6	K424 L425 Q426 K430 L434	K424-T428 PolarHBondContact O-N 3.25Å; K424-T428 PolarHBondContact O-OG1 3.04Å; L425-T428 PolarHBondContact O-N 3.49Å; L425-T428 VanDerWaalsContact O-N 3.15Å; Q426-T428 VanDerWaalsContact C-N 3.3Å; Q426-T428 PolarHBondContact O-N 3.27Å; T428-K430 PolarHBondContact O-N 3.41Å; T428-L434 WeakPolarHBondContact O-CD2 3.4Å
429	N	59.7	Low	75.7	Confident	161 Å²	161	97.6 Å²	97.6	86%	0.861	49%	0.488	S	S	*	.			trans	-69.4	80.3	-176.9	-90.3	-28.1	0	0	0	114	F427	F427-N429 PolarHBondContact O-N 2.94Å
430	K	65.6	Low	75.5	Confident	152 Å²	152	96.4 Å²	96.4	66%	0.661	49%	0.488	S	S	*	.			trans	-129.3	122.5	165	-71.3	-171.3	178.7	176.3	0	110.3	T428 L434	T428-K430 PolarHBondContact O-N 3.41Å; K430-L434 WeakPolarHBondContact O-CB 3.39Å; K430-L434 WeakPolarHBondContact O-CD2 3.45Å
431	P	61.6	Low	75.3	Confident	105 Å²	105	93.4 Å²	93.4	68%	0.682	47%	0.474	S	S	*	.			trans	-81.9	-37.6	-160.3	25.4	-30.8	0	0	0	116.6
432	D	60.3	Low	75.3	Confident	147 Å²	147	96.6 Å²	96.6	79%	0.786	48%	0.481	S	S	*	.	S	Bend	trans	-106.1	-30.1	-160.2	-62.7	-27.4	0	0	0	116.9
433	K	62.3	Low	75.6	Confident	197 Å²	197	101.8 Å²	101.8	86%	0.857	51%	0.505	S	S	*	.	S	Bend	trans	-89.6	-4.8	171.6	-68.9	-171.6	178.8	-175.6	0	113.4
434	L	67.8	Low	75.8	Confident	23 Å²	23	103.6 Å²	103.6	12%	0.12	51%	0.506	C	S	.	.	H	α-helix	trans	-90	-25.9	-173.8	-167.3	76.3	0	0	0	112.1	L425 T428 K430 K438	L425-L434 HydrophobicContact CD2-CD1 4.28Å; T428-L434 WeakPolarHBondContact O-CD2 3.4Å; K430-L434 WeakPolarHBondContact O-CB 3.39Å; K430-L434 WeakPolarHBondContact O-CD2 3.45Å; L434-K438 HydrophobicContact CD2-CD 4.38Å; L434-K438 VanDerWaalsContact CD2-CE 3.49Å; L434-K438 HydrophobicContact CG-CD 4.17Å; L434-K438 HydrophobicContact CG-CG 4.37Å; L434-K438 WeakPolarHBondContact O-CB 3.36Å; L434-K438 WeakPolarHBondContact O-CG 3.48Å; L434-K438 PolarHBondContact O-N 3.36Å
435	Q	76.4	Confident	76.2	Confident	98 Å²	98	97.5 Å²	97.5	46%	0.458	48%	0.48	S	S	.	.	H	α-helix	trans	-67.8	-47.8	-178.7	-171.5	56.3	41.7	0	0	111.5	A437 K438 D439	Q435-A437 PolarHBondContact O-N 3.34Å; Q435-K438 WeakPolarHBondContact O-CB 3.36Å; Q435-K438 PolarHBondContact O-N 2.88Å; Q435-K438 VanDerWaalsContact O-N 3.12Å; Q435-D439 PolarHBondContact NE2-OD1 3.18Å; Q435-D439 PolarHBondContact NE2-OD2 3.45Å; Q435-D439 VanDerWaalsContact NE2-OD2 3.14Å; Q435-D439 VanDerWaalsContact O-CG 3.27Å; Q435-D439 PolarHBondContact O-N 3.16Å
436	Q	78.2	Confident	76.9	Confident	134 Å²	134	101.6 Å²	101.6	63%	0.626	50%	0.498	S	S	*	.	H	α-helix	trans	-58.7	-46.1	174.7	-175.1	-178.4	-7.1	0	0	111.8	K438 D439 E440	Q436-K438 VanDerWaalsContact C-N 3.28Å; Q436-K438 PolarHBondContact O-N 2.85Å; Q436-D439 PolarHBondContact O-N 2.93Å; Q436-E440 WeakPolarHBondContact CG-OE1 3.43Å; Q436-E440 PolarHBondContact NE2-OE1 3.28Å; Q436-E440 WeakPolarHBondContact O-CB 3.24Å; Q436-E440 WeakPolarHBondContact O-CG 3.26Å; Q436-E440 PolarHBondContact O-N 3.42Å
437	A	78.7	Confident	77.9	Confident	33 Å²	33	102.1 Å²	102.1	27%	0.273	50%	0.5	S	S	.	.	H	α-helix	trans	-64.6	-30.7	177.1	0	0	0	0	0	113.1	Q435 I441	Q435-A437 PolarHBondContact O-N 3.34Å; A437-I441 WeakPolarHBondContact O-CB 3.32Å; A437-I441 WeakPolarHBondContact O-CD1 3.05Å; A437-I441 WeakPolarHBondContact O-CG1 3.34Å; A437-I441 PolarHBondContact O-N 3.19Å; A437-I441 VanDerWaalsContact O-N 3.09Å
438	K	78.1	Confident	78.8	Confident	49 Å²	49	94.1 Å²	94.1	21%	0.213	47%	0.466	C	S	.	.	H	α-helix	trans	-70.3	-41.9	173.4	-80.9	171.5	173.7	179	0	111.5	L434 Q435 Q436 I441 K442	L434-K438 HydrophobicContact CD2-CD 4.38Å; L434-K438 VanDerWaalsContact CD2-CE 3.49Å; L434-K438 HydrophobicContact CG-CD 4.17Å; L434-K438 HydrophobicContact CG-CG 4.37Å; L434-K438 WeakPolarHBondContact O-CB 3.36Å; L434-K438 WeakPolarHBondContact O-CG 3.48Å; L434-K438 PolarHBondContact O-N 3.36Å; Q435-K438 WeakPolarHBondContact O-CB 3.36Å; Q435-K438 PolarHBondContact O-N 2.88Å; Q435-K438 VanDerWaalsContact O-N 3.12Å; Q436-K438 VanDerWaalsContact C-N 3.28Å; Q436-K438 PolarHBondContact O-N 2.85Å; K438-I441 PolarHBondContact O-N 3.47Å; K438-K442 WeakPolarHBondContact O-CB 3.5Å; K438-K442 VanDerWaalsContact O-CG 3.31Å; K438-K442 WeakPolarHBondContact O-CG 3.28Å; K438-K442 PolarHBondContact O-N 3.14Å
439	D	83.8	Confident	80.1	Confident	78 Å²	78	93.8 Å²	93.8	42%	0.417	46%	0.459	S	S	.	.	H	α-helix	trans	-68.7	-40.9	179.5	-63	-28.2	0	0	0	110.5	Q435 Q436 K442 E443	Q435-D439 PolarHBondContact NE2-OD1 3.18Å; Q435-D439 PolarHBondContact NE2-OD2 3.45Å; Q435-D439 VanDerWaalsContact NE2-OD2 3.14Å; Q435-D439 VanDerWaalsContact O-CG 3.27Å; Q435-D439 PolarHBondContact O-N 3.16Å; Q436-D439 PolarHBondContact O-N 2.93Å; D439-K442 PolarHBondContact O-N 3.42Å; D439-E443 PolarHBondContact O-N 2.8Å
440	E	85.9	Confident	81.8	Confident	98 Å²	98	87.7 Å²	87.7	46%	0.458	44%	0.435	S	S	.	.	H	α-helix	trans	-60.2	-45.2	172.1	-72.7	170.1	-170.2	0	0	112.3	Q436 K442 E443 E444	Q436-E440 WeakPolarHBondContact CG-OE1 3.43Å; Q436-E440 PolarHBondContact NE2-OE1 3.28Å; Q436-E440 WeakPolarHBondContact O-CB 3.24Å; Q436-E440 WeakPolarHBondContact O-CG 3.26Å; Q436-E440 PolarHBondContact O-N 3.42Å; E440-K442 VanDerWaalsContact C-N 3.34Å; E440-K442 PolarHBondContact O-N 2.94Å; E440-E443 PolarHBondContact O-N 3.48Å; E440-E444 WeakPolarHBondContact O-CG 3.25Å; E440-E444 PolarHBondContact O-N 3.31Å
441	I	85.5	Confident	83.2	Confident	25 Å²	25	85 Å²	85	13%	0.128	42%	0.423	C	S	.	.	H	α-helix	trans	-67.4	-35.1	178.4	-73.1	170.7	0	0	0	112	E422 L425 A437 K438 E444 I445	E422-I441 HydrophobicContact CB-CG2 3.78Å; E422-I441 HydrophobicContact CG-CG2 3.92Å; L425-I441 HydrophobicContact CD1-CD1 3.11Å; A437-I441 WeakPolarHBondContact O-CB 3.32Å; A437-I441 WeakPolarHBondContact O-CD1 3.05Å; A437-I441 WeakPolarHBondContact O-CG1 3.34Å; A437-I441 PolarHBondContact O-N 3.19Å; A437-I441 VanDerWaalsContact O-N 3.09Å; K438-I441 PolarHBondContact O-N 3.47Å; I441-E444 PolarHBondContact O-N 3.44Å; I441-I445 HydrophobicContact CG2-CD1 3.92Å; I441-I445 HydrophobicContact CG2-CG1 4.46Å; I441-I445 WeakPolarHBondContact O-CB 3.46Å; I441-I445 VanDerWaalsContact O-CG1 3.29Å; I441-I445 WeakPolarHBondContact O-CG1 3.25Å; I441-I445 PolarHBondContact O-N 2.96Å
442	K	86.6	Confident	84.9	Confident	107 Å²	107	80.7 Å²	80.7	47%	0.465	40%	0.395	S	S	.	.	H	α-helix	trans	-65.1	-43.1	175	-79.8	176.7	177.8	-177.8	0	111.7	K438 D439 E440 I445 E446	K438-K442 WeakPolarHBondContact O-CB 3.5Å; K438-K442 VanDerWaalsContact O-CG 3.31Å; K438-K442 WeakPolarHBondContact O-CG 3.28Å; K438-K442 PolarHBondContact O-N 3.14Å; D439-K442 PolarHBondContact O-N 3.42Å; E440-K442 VanDerWaalsContact C-N 3.34Å; E440-K442 PolarHBondContact O-N 2.94Å; K442-I445 PolarHBondContact O-N 3.02Å; K442-E446 PolarHBondContact O-N 3.19Å
443	E	89.8	Confident	86.6	Confident	141 Å²	141	78.5 Å²	78.5	66%	0.659	38%	0.38	S	S	*	.	H	α-helix	trans	-61.1	-44.2	175.3	-171.5	176.9	-179.3	0	0	111.2	D439 E440 I445 E446 E447	D439-E443 PolarHBondContact O-N 2.8Å; E440-E443 PolarHBondContact O-N 3.48Å; E443-I445 VanDerWaalsContact C-N 3.33Å; E443-I445 PolarHBondContact O-N 3.14Å; E443-E446 PolarHBondContact O-N 3.47Å; E443-E447 PolarHBondContact O-N 3.43Å
444	E	90.8	Very high	88.2	Confident	77 Å²	77	73 Å²	73	36%	0.36	36%	0.357	S	S	.	.	H	α-helix	trans	-62.2	-37.6	174.5	-71.9	-177.5	172.7	0	0	113	K418 E440 I441 L448	K418-E444 VanDerWaalsContact CE-OE2 3.3Å; K418-E444 WeakPolarHBondContact CE-OE2 3.46Å; K418-E444 IonicContact NZ-OE1 2.67Å; K418-E444 IonicContact NZ-OE2 2.94Å; K418-E444 PolarHBondContact NZ-OE2 3.43Å; E440-E444 WeakPolarHBondContact O-CG 3.25Å; E440-E444 PolarHBondContact O-N 3.31Å; I441-E444 PolarHBondContact O-N 3.44Å; E444-L448 WeakPolarHBondContact O-CB 3.33Å; E444-L448 VanDerWaalsContact O-CG 3.27Å; E444-L448 WeakPolarHBondContact O-CG 3.47Å; E444-L448 PolarHBondContact O-N 3.2Å
445	I	92.8	Very high	89.5	Confident	12 Å²	12	72.2 Å²	72.2	6%	0.062	36%	0.355	C	S	.	.	H	α-helix	trans	-64.9	-45.5	175.7	-76.7	169.9	0	0	0	110.2	L415 K418 R419 E422 I441 K442 E443 E447 L448 E449	L415-I445 HydrophobicContact CD1-CG2 3.98Å; K418-I445 HydrophobicContact CB-CG1 4.13Å; R419-I445 HydrophobicContact CG-CD1 4.18Å; E422-I445 HydrophobicContact CB-CD1 4.01Å; E422-I445 HydrophobicContact CG-CD1 4.35Å; E422-I445 WeakPolarHBondContact OE2-CD1 3.19Å; I441-I445 HydrophobicContact CG2-CD1 3.92Å; I441-I445 HydrophobicContact CG2-CG1 4.46Å; I441-I445 WeakPolarHBondContact O-CB 3.46Å; I441-I445 VanDerWaalsContact O-CG1 3.29Å; I441-I445 WeakPolarHBondContact O-CG1 3.25Å; I441-I445 PolarHBondContact O-N 2.96Å; K442-I445 PolarHBondContact O-N 3.02Å; E443-I445 VanDerWaalsContact C-N 3.33Å; E443-I445 PolarHBondContact O-N 3.14Å; I445-E447 VanDerWaalsContact C-N 3.34Å; I445-E447 PolarHBondContact O-N 3.2Å; I445-L448 PolarHBondContact O-N 2.84Å; I445-E449 HydrophobicContact CG2-CG 4.32Å; I445-E449 WeakPolarHBondContact O-CB 3.36Å; I445-E449 VanDerWaalsContact O-CG 3.31Å; I445-E449 WeakPolarHBondContact O-CG 3.49Å; I445-E449 PolarHBondContact O-N 2.91Å
446	E	94.1	Very high	90.4	Very high	143 Å²	143	72.3 Å²	72.3	67%	0.668	36%	0.356	S	S	*	.	H	α-helix	trans	-61.6	-41.9	178	-171.3	173	-176.3	0	0	111.4	K442 E443 L448 E449 G450	K442-E446 PolarHBondContact O-N 3.19Å; E443-E446 PolarHBondContact O-N 3.47Å; E446-L448 PolarHBondContact O-N 2.95Å; E446-E449 PolarHBondContact O-N 2.99Å; E446-G450 PolarHBondContact O-N 3.35Å
447	E	94.4	Very high	91.3	Very high	113 Å²	113	72 Å²	72	53%	0.528	35%	0.349	S	S	.	.	H	α-helix	trans	-62.3	-43.5	174.5	-165	-162.7	159.6	0	0	111.8	E443 I445 G450 K451	E443-E447 PolarHBondContact O-N 3.43Å; I445-E447 VanDerWaalsContact C-N 3.34Å; I445-E447 PolarHBondContact O-N 3.2Å; E447-G450 PolarHBondContact O-N 3.31Å; E447-K451 WeakPolarHBondContact O-CG 3.34Å; E447-K451 PolarHBondContact O-N 3Å; E447-K451 WeakPolarHBondContact OE1-CE 3.21Å; E447-K451 IonicContact OE1-NZ 3.65Å; E447-K451 PolarHBondContact OE1-NZ 3.03Å; E447-K451 IonicContact OE2-NZ 2.8Å
448	L	93.8	Very high	92.2	Very high	11 Å²	11	73.4 Å²	73.4	6%	0.058	35%	0.352	C	S	.	.	H	α-helix	trans	-68.9	-36.9	178.4	-74.5	170.2	0	0	0	112.4	L414 L415 K418 E444 I445 E446 G450 K451 V452	L414-L448 HydrophobicContact CB-CD2 4.46Å; L414-L448 HydrophobicContact CD2-CD1 4.42Å; L414-L448 HydrophobicContact CD2-CD2 3.63Å; L414-L448 HydrophobicContact CG-CD1 4.02Å; L414-L448 HydrophobicContact CG-CD2 3.96Å; L415-L448 HydrophobicContact CB-CB 4.19Å; L415-L448 HydrophobicContact CD1-CB 3.91Å; K418-L448 HydrophobicContact CB-CD1 4.16Å; K418-L448 HydrophobicContact CG-CD1 3.69Å; E444-L448 WeakPolarHBondContact O-CB 3.33Å; E444-L448 VanDerWaalsContact O-CG 3.27Å; E444-L448 WeakPolarHBondContact O-CG 3.47Å; E444-L448 PolarHBondContact O-N 3.2Å; I445-L448 PolarHBondContact O-N 2.84Å; E446-L448 PolarHBondContact O-N 2.95Å; L448-G450 VanDerWaalsContact C-N 3.32Å; L448-K451 HydrophobicContact CD2-CD 4.29Å; L448-K451 PolarHBondContact O-N 3.45Å; L448-V452 WeakPolarHBondContact O-CG2 3.36Å; L448-V452 PolarHBondContact O-N 3.34Å
449	E	95.3	Very high	93	Very high	65 Å²	65	72.2 Å²	72.2	30%	0.304	35%	0.347	S	S	.	.	H	α-helix	trans	-59.6	-45	171.4	-76.4	177.4	179.3	0	0	110.7	L415 R419 I445 E446 K451 V452 Q453	L415-E449 HydrophobicContact CD1-CG 3.77Å; L415-E449 HydrophobicContact CD2-CG 3.77Å; L415-E449 HydrophobicContact CG-CG 4.44Å; R419-E449 IonicContact CZ-OE1 3.57Å; R419-E449 IonicContact NE-OE1 3.2Å; R419-E449 IonicContact NH2-OE1 2.67Å; R419-E449 PolarHBondContact NH2-OE1 3.43Å; I445-E449 HydrophobicContact CG2-CG 4.32Å; I445-E449 WeakPolarHBondContact O-CB 3.36Å; I445-E449 VanDerWaalsContact O-CG 3.31Å; I445-E449 WeakPolarHBondContact O-CG 3.49Å; I445-E449 PolarHBondContact O-N 2.91Å; E446-E449 PolarHBondContact O-N 2.99Å; E449-K451 VanDerWaalsContact C-N 3.34Å; E449-K451 PolarHBondContact O-N 3.17Å; E449-V452 PolarHBondContact O-N 3.49Å; E449-Q453 WeakPolarHBondContact O-CG 3.41Å; E449-Q453 PolarHBondContact O-N 3.14Å
450	G	96.4	Very high	93.6	Very high	34 Å²	34	72.9 Å²	72.9	35%	0.351	35%	0.347	S	S	.	.	H	α-helix	trans	-57.5	-44.1	172.7	0	0	0	0	0	112.7	E446 E447 L448 Q453 Q454	E446-G450 PolarHBondContact O-N 3.35Å; E447-G450 PolarHBondContact O-N 3.31Å; L448-G450 VanDerWaalsContact C-N 3.32Å; G450-Q453 PolarHBondContact O-N 3.17Å; G450-Q454 WeakPolarHBondContact O-CB 3.46Å; G450-Q454 PolarHBondContact O-N 3.43Å
451	K	95.6	Very high	94.1	Very high	94 Å²	94	73.6 Å²	73.6	41%	0.409	35%	0.35	S	S	.	.	H	α-helix	trans	-64.8	-40.8	176.5	-73.9	172.6	-175.6	162.3	0	112.8	E447 L448 E449 Q454 G455	E447-K451 WeakPolarHBondContact O-CG 3.34Å; E447-K451 PolarHBondContact O-N 3Å; E447-K451 WeakPolarHBondContact OE1-CE 3.21Å; E447-K451 IonicContact OE1-NZ 3.65Å; E447-K451 PolarHBondContact OE1-NZ 3.03Å; E447-K451 IonicContact OE2-NZ 2.8Å; L448-K451 HydrophobicContact CD2-CD 4.29Å; L448-K451 PolarHBondContact O-N 3.45Å; E449-K451 VanDerWaalsContact C-N 3.34Å; E449-K451 PolarHBondContact O-N 3.17Å; K451-Q454 PolarHBondContact O-N 3.19Å; K451-G455 PolarHBondContact O-N 3.48Å
452	V	96.3	Very high	94.6	Very high	16 Å²	16	72.5 Å²	72.5	10%	0.097	35%	0.345	C	S	.	.	H	α-helix	trans	-64.2	-47.4	176.8	170.7	0	0	0	0	110.5	W408 S411 Q412 L415 L448 E449 Q454 G455 E456	W408-V452 PolarHBondContact NE1-O 2.95Å; S411-V452 VanDerWaalsContact C-CG2 3.49Å; Q412-V452 HydrophobicContact CB-CG2 4.26Å; L415-V452 HydrophobicContact CB-CG2 4.26Å; L415-V452 HydrophobicContact CD2-CG2 3.99Å; L448-V452 WeakPolarHBondContact O-CG2 3.36Å; L448-V452 PolarHBondContact O-N 3.34Å; E449-V452 PolarHBondContact O-N 3.49Å; V452-Q454 VanDerWaalsContact C-N 3.31Å; V452-Q454 PolarHBondContact O-N 3.28Å; V452-G455 PolarHBondContact O-N 2.67Å; V452-E456 PolarHBondContact O-N 3.18Å
453	Q	96.7	Very high	95.1	Very high	101 Å²	101	67.8 Å²	67.8	47%	0.472	33%	0.325	S	S	.	.	H	α-helix	trans	-62.2	-38.9	177	-70.2	178.2	13.7	0	0	112	E449 G450 R457	E449-Q453 WeakPolarHBondContact O-CG 3.41Å; E449-Q453 PolarHBondContact O-N 3.14Å; G450-Q453 PolarHBondContact O-N 3.17Å; Q453-R457 WeakPolarHBondContact O-CG 3.44Å; Q453-R457 PolarHBondContact O-N 2.93Å; Q453-R457 VanDerWaalsContact O-N 3.07Å
454	Q	96.2	Very high	95.5	Very high	80 Å²	80	66 Å²	66	37%	0.374	32%	0.316	S	S	.	.	H	α-helix	trans	-66.2	-43.9	175.1	-172.7	59.5	40	0	0	111.6	G450 K451 V452 E456 R457 D458	G450-Q454 WeakPolarHBondContact O-CB 3.46Å; G450-Q454 PolarHBondContact O-N 3.43Å; K451-Q454 PolarHBondContact O-N 3.19Å; V452-Q454 VanDerWaalsContact C-N 3.31Å; V452-Q454 PolarHBondContact O-N 3.28Å; Q454-E456 VanDerWaalsContact C-N 3.32Å; Q454-E456 PolarHBondContact O-N 3.11Å; Q454-R457 PolarHBondContact O-N 2.92Å; Q454-D458 PolarHBondContact NE2-OD1 2.81Å; Q454-D458 WeakPolarHBondContact O-CB 3.08Å; Q454-D458 PolarHBondContact O-N 3.43Å
455	G	95.1	Very high	95.8	Very high	8 Å²	8	62.8 Å²	62.8	8%	0.082	30%	0.301	C	S	.	.	H	α-helix	trans	-60.5	-40.2	177	0	0	0	0	0	112.9	K451 V452 D458 F459	K451-G455 PolarHBondContact O-N 3.48Å; V452-G455 PolarHBondContact O-N 2.67Å; G455-D458 PolarHBondContact O-N 2.81Å; G455-F459 WeakPolarHBondContact O-CB 3.37Å; G455-F459 PolarHBondContact O-N 2.81Å
456	E	95.3	Very high	96.1	Very high	100 Å²	100	62.2 Å²	62.2	47%	0.467	30%	0.298	S	S	.	.	H	α-helix	trans	-62.8	-47.4	174.2	-174.1	173.5	-162.2	0	0	111.6	W408 V452 Q454 D458 F459 E460	W408-E456 HydrophobicContact CD2-CB 4.37Å; W408-E456 HydrophobicContact CH2-CG 4.13Å; W408-E456 HydrophobicContact CZ2-CB 3.84Å; W408-E456 HydrophobicContact CZ2-CG 3.67Å; V452-E456 PolarHBondContact O-N 3.18Å; Q454-E456 VanDerWaalsContact C-N 3.32Å; Q454-E456 PolarHBondContact O-N 3.11Å; E456-D458 PolarHBondContact O-N 2.78Å; E456-F459 PolarHBondContact O-N 3.04Å; E456-E460 WeakPolarHBondContact O-CB 3.49Å; E456-E460 PolarHBondContact O-N 3.17Å
457	R	96.9	Very high	96.2	Very high	128 Å²	128	60.5 Å²	60.5	48%	0.483	29%	0.286	S	S	.	.	H	α-helix	trans	-60.7	-44.5	175.8	-74.1	-171.8	-64.9	-97.8	3.3	112.3	Q453 Q454 F459 E460 Q461	Q453-R457 WeakPolarHBondContact O-CG 3.44Å; Q453-R457 PolarHBondContact O-N 2.93Å; Q453-R457 VanDerWaalsContact O-N 3.07Å; Q454-R457 PolarHBondContact O-N 2.92Å; R457-F459 VanDerWaalsContact C-N 3.34Å; R457-E460 PolarHBondContact O-N 3.03Å; R457-Q461 VanDerWaalsContact O-CB 3.28Å; R457-Q461 WeakPolarHBondContact O-CB 3.46Å; R457-Q461 PolarHBondContact O-N 2.93Å
458	D	96.1	Very high	96.4	Very high	62 Å²	62	62.8 Å²	62.8	33%	0.332	29%	0.294	S	S	.	.	H	α-helix	trans	-62.6	-42.9	178.6	-69.8	-15.5	0	0	0	110.8	T404 Q454 G455 E456 Q461 I462	T404-D458 HydrophobicContact CG2-CB 3.87Å; Q454-D458 PolarHBondContact NE2-OD1 2.81Å; Q454-D458 WeakPolarHBondContact O-CB 3.08Å; Q454-D458 PolarHBondContact O-N 3.43Å; G455-D458 PolarHBondContact O-N 2.81Å; E456-D458 PolarHBondContact O-N 2.78Å; D458-Q461 PolarHBondContact O-N 3.21Å; D458-I462 VanDerWaalsContact O-CG2 3.3Å; D458-I462 WeakPolarHBondContact O-CG2 3.39Å; D458-I462 PolarHBondContact O-N 2.9Å
459	F	95.4	Very high	96.5	Very high	24 Å²	24	62.9 Å²	62.9	11%	0.105	29%	0.294	C	S	.	.	H	α-helix	trans	-65.6	-42.4	178.1	179.8	-108.9	0	0	0	112.7	M290 R401 T404 W405 W408 G455 E456 R457 I462 S463	M290-F459 HydrophobicContact CE-CE2 4.1Å; M290-F459 HydrophobicContact CE-CZ 3.79Å; R401-F459 HydrophobicContact CG-CD2 4.14Å; R401-F459 HydrophobicContact CG-CE2 3.59Å; T404-F459 HydrophobicContact CG2-CB 4.13Å; W405-F459 HydrophobicContact CB-CD2 3.71Å; W405-F459 HydrophobicContact CB-CE2 3.55Å; W405-F459 HydrophobicContact CB-CZ 4.31Å; W405-F459 AromaticContact CD1-CE2 3.92Å; W405-F459 AromaticContact CD1-CZ 3.82Å; W405-F459 HydrophobicContact CG-CD2 4.47Å; W405-F459 HydrophobicContact CG-CE2 4.09Å; W405-F459 HydrophobicContact CG-CZ 4.39Å; W408-F459 HydrophobicContact CE3-CB 4.24Å; W408-F459 AromaticContact CE3-CD1 4Å; W408-F459 HydrophobicContact CE3-CD1 4Å; W408-F459 HydrophobicContact CE3-CG 4.17Å; W408-F459 AromaticContact CZ3-CD1 3.74Å; W408-F459 HydrophobicContact CZ3-CD1 3.74Å; W408-F459 HydrophobicContact CZ3-CE1 4.18Å; W408-F459 HydrophobicContact CZ3-CG 4.37Å; G455-F459 WeakPolarHBondContact O-CB 3.37Å; G455-F459 PolarHBondContact O-N 2.81Å; E456-F459 PolarHBondContact O-N 3.04Å; R457-F459 VanDerWaalsContact C-N 3.34Å; F459-I462 VanDerWaalsContact O-CG2 3.24Å; F459-I462 WeakPolarHBondContact O-CG2 3.37Å; F459-S463 VanDerWaalsContact O-CB 3.29Å; F459-S463 WeakPolarHBondContact O-CB 3.49Å; F459-S463 PolarHBondContact O-N 3.47Å; F459-S463 PolarHBondContact O-OG 3.49Å
460	E	95.9	Very high	96.6	Very high	92 Å²	92	59.8 Å²	59.8	43%	0.43	28%	0.279	S	S	.	.	H	α-helix	trans	-64.8	-42.5	175.5	-179.9	58.7	-158.1	0	0	111.1	E456 R457 S463 K464	E456-E460 WeakPolarHBondContact O-CB 3.49Å; E456-E460 PolarHBondContact O-N 3.17Å; R457-E460 PolarHBondContact O-N 3.03Å; E460-S463 PolarHBondContact O-N 2.52Å; E460-K464 HydrophobicContact CG-CD 4.33Å; E460-K464 WeakPolarHBondContact O-CG 3.46Å; E460-K464 PolarHBondContact O-N 3.02Å; E460-K464 WeakPolarHBondContact OE1-CE 3.38Å; E460-K464 IonicContact OE1-NZ 3.54Å; E460-K464 PolarHBondContact OE1-NZ 3.34Å
461	Q	97.3	Very high	96.6	Very high	112 Å²	112	60.8 Å²	60.8	52%	0.523	28%	0.281	S	S	.	.	H	α-helix	trans	-66.2	-47.9	-179.9	-176	59	34.6	0	0	112.1	R457 D458 S463 K464 T465	R457-Q461 VanDerWaalsContact O-CB 3.28Å; R457-Q461 WeakPolarHBondContact O-CB 3.46Å; R457-Q461 PolarHBondContact O-N 2.93Å; D458-Q461 PolarHBondContact O-N 3.21Å; Q461-S463 VanDerWaalsContact C-N 3.28Å; Q461-S463 PolarHBondContact O-N 3.33Å; Q461-K464 PolarHBondContact O-N 3.16Å; Q461-T465 PolarHBondContact O-N 2.93Å; Q461-T465 PolarHBondContact O-OG1 2.96Å; Q461-T465 VanDerWaalsContact O-OG1 3.06Å
462	I	96.9	Very high	96.6	Very high	3 Å²	3	58.7 Å²	58.7	2%	0.015	27%	0.27	C	S	.	.	H	α-helix	trans	-62.6	-38.5	177.2	-171	168.1	0	0	0	111	H400 R401 T404 D458 F459 K464 T465 I466	H400-I462 HydrophobicContact CB-CD1 4.04Å; R401-I462 HydrophobicContact CB-CD1 4.28Å; R401-I462 HydrophobicContact CB-CG1 4.47Å; R401-I462 HydrophobicContact CB-CG2 4.35Å; R401-I462 HydrophobicContact CG-CG2 4.25Å; T404-I462 HydrophobicContact CG2-CG2 4.28Å; D458-I462 VanDerWaalsContact O-CG2 3.3Å; D458-I462 WeakPolarHBondContact O-CG2 3.39Å; D458-I462 PolarHBondContact O-N 2.9Å; F459-I462 VanDerWaalsContact O-CG2 3.24Å; F459-I462 WeakPolarHBondContact O-CG2 3.37Å; I462-K464 PolarHBondContact O-N 3.04Å; I462-T465 PolarHBondContact O-N 3.29Å; I462-I466 HydrophobicContact CD1-CD1 4.35Å; I462-I466 HydrophobicContact CG1-CD1 3.78Å; I462-I466 HydrophobicContact CG1-CG1 4.22Å; I462-I466 WeakPolarHBondContact O-CB 3.5Å; I462-I466 VanDerWaalsContact O-CG1 3.27Å; I462-I466 WeakPolarHBondContact O-CG1 3.31Å; I462-I466 PolarHBondContact O-N 3.47Å
463	S	96.6	Very high	96.6	Very high	8 Å²	8	58.4 Å²	58.4	6%	0.056	27%	0.268	C	S	.	.	H	α-helix	trans	-62.1	-44.9	177.4	-61.6	0	0	0	0	111.7	R401 F459 E460 Q461 I466 R467	R401-S463 WeakPolarHBondContact CD-OG 3.47Å; R401-S463 PolarHBondContact NE-OG 3.35Å; F459-S463 VanDerWaalsContact O-CB 3.29Å; F459-S463 WeakPolarHBondContact O-CB 3.49Å; F459-S463 PolarHBondContact O-N 3.47Å; F459-S463 PolarHBondContact O-OG 3.49Å; E460-S463 PolarHBondContact O-N 2.52Å; Q461-S463 VanDerWaalsContact C-N 3.28Å; Q461-S463 PolarHBondContact O-N 3.33Å; S463-I466 PolarHBondContact O-N 3.2Å; S463-R467 WeakPolarHBondContact O-CG 3.49Å; S463-R467 PolarHBondContact O-N 3.44Å; S463-R467 VanDerWaalsContact O-N 3.12Å
464	K	97.4	Very high	96.6	Very high	104 Å²	104	55.4 Å²	55.4	45%	0.452	25%	0.254	S	S	.	.	H	α-helix	trans	-61.7	-44	174.5	-79.3	170	165.6	139.3	0	112.6	E460 Q461 I462 K468	E460-K464 HydrophobicContact CG-CD 4.33Å; E460-K464 WeakPolarHBondContact O-CG 3.46Å; E460-K464 PolarHBondContact O-N 3.02Å; E460-K464 WeakPolarHBondContact OE1-CE 3.38Å; E460-K464 IonicContact OE1-NZ 3.54Å; E460-K464 PolarHBondContact OE1-NZ 3.34Å; Q461-K464 PolarHBondContact O-N 3.16Å; I462-K464 PolarHBondContact O-N 3.04Å; K464-K468 PolarHBondContact O-N 3.42Å
465	T	97.9	Very high	96.5	Very high	9 Å²	9	57.5 Å²	57.5	6%	0.055	26%	0.262	C	S	.	.	H	α-helix	trans	-62.3	-48.1	177.5	-55.1	0	0	0	0	110.8	I192 Y194 Q461 I462 R467 K468 E469	I192-T465 VanDerWaalsContact O-CB 3.27Å; I192-T465 WeakPolarHBondContact O-CB 3.38Å; I192-T465 WeakPolarHBondContact O-CG2 3.44Å; I192-T465 PolarHBondContact O-OG1 3.39Å; Y194-T465 HydrophobicContact CD1-CG2 3.91Å; Y194-T465 HydrophobicContact CD2-CG2 4.08Å; Y194-T465 HydrophobicContact CE1-CG2 3.8Å; Y194-T465 HydrophobicContact CE2-CG2 3.97Å; Y194-T465 HydrophobicContact CG-CG2 4.03Å; Q461-T465 PolarHBondContact O-N 2.93Å; Q461-T465 PolarHBondContact O-OG1 2.96Å; Q461-T465 VanDerWaalsContact O-OG1 3.06Å; I462-T465 PolarHBondContact O-N 3.29Å; T465-R467 VanDerWaalsContact C-N 3.31Å; T465-R467 PolarHBondContact O-N 3.35Å; T465-K468 PolarHBondContact O-N 3.03Å; T465-K468 VanDerWaalsContact O-N 3.15Å; T465-E469 HydrophobicContact CG2-CG 4.17Å; T465-E469 WeakPolarHBondContact O-CB 3.37Å; T465-E469 WeakPolarHBondContact O-CG 3.46Å; T465-E469 PolarHBondContact O-N 2.93Å
466	I	97.8	Very high	96.4	Very high	0 Å²	0	59.6 Å²	59.6	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-60.7	-40.6	-178.3	-69.5	170.4	0	0	0	111.5	F297 V397 F398 R401 I462 S463 K468 E469 V470	F297-I466 HydrophobicContact CE1-CB 4.19Å; F297-I466 HydrophobicContact CE1-CG2 3.75Å; F297-I466 HydrophobicContact CZ-CB 4.42Å; F297-I466 HydrophobicContact CZ-CG2 4.38Å; V397-I466 HydrophobicContact CB-CD1 4.13Å; V397-I466 HydrophobicContact CB-CG1 4.09Å; V397-I466 HydrophobicContact CG2-CD1 4.36Å; V397-I466 HydrophobicContact CG2-CG1 4.11Å; V397-I466 HydrophobicContact CG2-CG2 4.3Å; V397-I466 WeakPolarHBondContact O-CD1 3.4Å; F398-I466 HydrophobicContact CD1-CG2 3.85Å; F398-I466 HydrophobicContact CE1-CG2 3.48Å; F398-I466 VanDerWaalsContact CE1-CG2 3.48Å; R401-I466 HydrophobicContact CB-CD1 3.68Å; R401-I466 HydrophobicContact CG-CD1 4.45Å; I462-I466 HydrophobicContact CD1-CD1 4.35Å; I462-I466 HydrophobicContact CG1-CD1 3.78Å; I462-I466 HydrophobicContact CG1-CG1 4.22Å; I462-I466 WeakPolarHBondContact O-CB 3.5Å; I462-I466 VanDerWaalsContact O-CG1 3.27Å; I462-I466 WeakPolarHBondContact O-CG1 3.31Å; I462-I466 PolarHBondContact O-N 3.47Å; S463-I466 PolarHBondContact O-N 3.2Å; I466-K468 VanDerWaalsContact C-N 3.34Å; I466-K468 PolarHBondContact O-N 3.23Å; I466-E469 PolarHBondContact O-N 3.25Å; I466-V470 HydrophobicContact CG2-CG2 3.91Å; I466-V470 WeakPolarHBondContact O-CB 3.43Å; I466-V470 VanDerWaalsContact O-CG2 3.32Å; I466-V470 WeakPolarHBondContact O-CG2 3.32Å; I466-V470 PolarHBondContact O-N 2.87Å
467	R	97.8	Very high	96.4	Very high	107 Å²	107	56.7 Å²	56.7	40%	0.404	25%	0.254	S	S	.	.	H	α-helix	trans	-57.8	-45.4	176.4	-75.4	175.8	174.7	-140.3	3	112.3	D294 W296 F297 S463 T465 S471	D294-R467 VanDerWaalsContact CG-NH2 3.32Å; D294-R467 IonicContact OD1-NH2 3.88Å; D294-R467 PolarHBondContact OD1-NH2 3.08Å; D294-R467 IonicContact OD2-CZ 2.62Å; D294-R467 IonicContact OD2-NH2 2.65Å; D294-R467 PolarHBondContact OD2-NH2 3.42Å; W296-R467 HydrophobicContact CD2-CG 4.29Å; W296-R467 HydrophobicContact CE3-CG 3.93Å; W296-R467 HydrophobicContact CH2-CB 4.24Å; W296-R467 HydrophobicContact CH2-CG 3.73Å; W296-R467 HydrophobicContact CZ2-CB 4.46Å; W296-R467 HydrophobicContact CZ2-CG 4.05Å; W296-R467 HydrophobicContact CZ3-CG 3.66Å; F297-R467 HydrophobicContact CZ-CG 4.29Å; S463-R467 WeakPolarHBondContact O-CG 3.49Å; S463-R467 PolarHBondContact O-N 3.44Å; S463-R467 VanDerWaalsContact O-N 3.12Å; T465-R467 VanDerWaalsContact C-N 3.31Å; T465-R467 PolarHBondContact O-N 3.35Å; R467-S471 WeakPolarHBondContact O-CB 3.28Å; R467-S471 PolarHBondContact O-N 2.98Å; R467-S471 VanDerWaalsContact O-N 3.13Å
468	K	97.3	Very high	96.3	Very high	160 Å²	160	54.5 Å²	54.5	70%	0.696	26%	0.255	S	S	*	.	H	α-helix	trans	-64.1	-43.7	177.1	-67.1	-179.8	179.8	-175.6	0	111.6	K464 T465 I466 S471 R472	K464-K468 PolarHBondContact O-N 3.42Å; T465-K468 PolarHBondContact O-N 3.03Å; T465-K468 VanDerWaalsContact O-N 3.15Å; I466-K468 VanDerWaalsContact C-N 3.34Å; I466-K468 PolarHBondContact O-N 3.23Å; K468-S471 PolarHBondContact O-N 3.05Å; K468-R472 PolarHBondContact O-N 3.46Å
469	E	97	Very high	96.2	Very high	13 Å²	13	58.5 Å²	58.5	6%	0.061	27%	0.269	C	S	.	.	H	α-helix	trans	-69	-41.7	-177.5	-76	-71.3	119.2	0	0	112.8	Y194 I195 H240 T465 I466 R472 F473	Y194-E469 HydrophobicContact CD1-CG 3.9Å; I195-E469 HydrophobicContact CD1-CB 3.82Å; I195-E469 HydrophobicContact CG1-CB 4.05Å; I195-E469 PolarHBondContact N-OE2 3.22Å; I195-E469 VanDerWaalsContact N-OE2 3.1Å; H240-E469 IonicContact CD2-OE2 2.81Å; H240-E469 IonicContact CE1-OE1 2.65Å; H240-E469 PolarHBondContact CE1-OE1 3.44Å; H240-E469 VanDerWaalsContact CE1-OE1 3.27Å; H240-E469 IonicContact CE1-OE2 3.62Å; H240-E469 IonicContact NE2-OE1 2.92Å; H240-E469 PolarHBondContact NE2-OE1 3.24Å; H240-E469 IonicContact NE2-OE2 2.66Å; H240-E469 PolarHBondContact NE2-OE2 3.39Å; H240-E469 VanDerWaalsContact NE2-OE2 3.09Å; T465-E469 HydrophobicContact CG2-CG 4.17Å; T465-E469 WeakPolarHBondContact O-CB 3.37Å; T465-E469 WeakPolarHBondContact O-CG 3.46Å; T465-E469 PolarHBondContact O-N 2.93Å; I466-E469 PolarHBondContact O-N 3.25Å; E469-R472 PolarHBondContact O-N 3.07Å; E469-R472 IonicContact OE2-NH1 2.72Å; E469-F473 VanDerWaalsContact O-CB 3.25Å; E469-F473 WeakPolarHBondContact O-CB 3.36Å; E469-F473 PolarHBondContact O-N 3.01Å
470	V	97.5	Very high	96.1	Very high	0 Å²	0	58.5 Å²	58.5	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-61.8	-44.2	173.2	167.4	0	0	0	0	110.7	W296 K300 F304 V394 F398 I466 R472 F473 E474	W296-V470 HydrophobicContact CH2-CB 3.98Å; W296-V470 HydrophobicContact CH2-CG1 4.04Å; W296-V470 HydrophobicContact CH2-CG2 4.16Å; W296-V470 HydrophobicContact CZ2-CB 4.37Å; W296-V470 HydrophobicContact CZ2-CG1 4.1Å; K300-V470 HydrophobicContact CD-CG1 4.34Å; F304-V470 HydrophobicContact CE2-CG1 3.79Å; F304-V470 HydrophobicContact CE2-CG2 4.32Å; F304-V470 HydrophobicContact CZ-CG1 4.08Å; V394-V470 HydrophobicContact CG1-CG2 4.29Å; F398-V470 HydrophobicContact CE1-CG2 4.22Å; F398-V470 HydrophobicContact CZ-CG2 4.08Å; I466-V470 HydrophobicContact CG2-CG2 3.91Å; I466-V470 WeakPolarHBondContact O-CB 3.43Å; I466-V470 VanDerWaalsContact O-CG2 3.32Å; I466-V470 WeakPolarHBondContact O-CG2 3.32Å; I466-V470 PolarHBondContact O-N 2.87Å; V470-R472 PolarHBondContact O-N 3.35Å; V470-F473 PolarHBondContact O-N 3.23Å; V470-E474 HydrophobicContact CG1-CG 4.42Å; V470-E474 WeakPolarHBondContact O-CG 3.43Å; V470-E474 PolarHBondContact O-N 3.07Å
471	S	96.5	Very high	96	Very high	55 Å²	55	55.6 Å²	55.6	39%	0.385	26%	0.256	S	S	.	.	H	α-helix	trans	-60.8	-46.4	177.1	-176.4	0	0	0	0	111.9	R467 K468 E474 K475	R467-S471 WeakPolarHBondContact O-CB 3.28Å; R467-S471 PolarHBondContact O-N 2.98Å; R467-S471 VanDerWaalsContact O-N 3.13Å; K468-S471 PolarHBondContact O-N 3.05Å; S471-E474 PolarHBondContact O-N 3.31Å; S471-K475 WeakPolarHBondContact O-CG 3.39Å; S471-K475 PolarHBondContact O-N 3.25Å; S471-K475 VanDerWaalsContact O-N 3.17Å
472	R	95.6	Very high	96	Very high	50 Å²	50	57.7 Å²	57.7	19%	0.189	26%	0.264	C	S	.	.	H	α-helix	trans	-59.8	-47.8	174.6	177.1	-178.5	160.7	-104.6	-15.3	111.4	H240 K468 E469 V470 E474 K475 E476	H240-R472 PolarHBondContact CD2-NH1 3.15Å; K468-R472 PolarHBondContact O-N 3.46Å; E469-R472 PolarHBondContact O-N 3.07Å; E469-R472 IonicContact OE2-NH1 2.72Å; V470-R472 PolarHBondContact O-N 3.35Å; R472-E474 VanDerWaalsContact C-N 3.35Å; R472-E474 PolarHBondContact O-N 3.15Å; R472-K475 PolarHBondContact O-N 3.42Å; R472-E476 HydrophobicContact CG-CG 4.47Å; R472-E476 IonicContact CZ-OE1 3.1Å; R472-E476 IonicContact CZ-OE2 3.81Å; R472-E476 IonicContact NE-OE1 2.76Å; R472-E476 PolarHBondContact NE-OE1 3.03Å; R472-E476 IonicContact NE-OE2 2.96Å; R472-E476 VanDerWaalsContact NH2-CD 3.28Å; R472-E476 IonicContact NH2-OE1 3.86Å; R472-E476 PolarHBondContact NH2-OE1 2.88Å; R472-E476 IonicContact NH2-OE2 3.14Å; R472-E476 PolarHBondContact NH2-OE2 3.32Å; R472-E476 WeakPolarHBondContact O-CG 3.49Å; R472-E476 PolarHBondContact O-N 3.11Å
473	F	96.2	Very high	95.9	Very high	11 Å²	11	63 Å²	63	5%	0.048	29%	0.29	C	S	.	.	H	α-helix	trans	-58.5	-44.9	-179.8	177.1	-96.8	0	0	0	112.2	I195 F304 Y387 L390 I391 V394 E469 V470 E476 R477	I195-F473 HydrophobicContact CD1-CB 3.86Å; I195-F473 HydrophobicContact CD1-CG 4.32Å; F304-F473 AromaticContact CE1-CD1 3.95Å; F304-F473 HydrophobicContact CE1-CD1 3.95Å; F304-F473 AromaticContact CE1-CE1 3.76Å; F304-F473 HydrophobicContact CE1-CE1 3.76Å; F304-F473 HydrophobicContact CZ-CD1 4.06Å; F304-F473 HydrophobicContact CZ-CE1 4.34Å; Y387-F473 HydrophobicContact CD1-CE2 4.29Å; Y387-F473 AromaticContact CD1-CZ 3.84Å; Y387-F473 HydrophobicContact CD1-CZ 3.84Å; Y387-F473 HydrophobicContact CE1-CE2 4.03Å; Y387-F473 AromaticContact CE1-CZ 3.92Å; Y387-F473 HydrophobicContact CE1-CZ 3.92Å; L390-F473 HydrophobicContact CB-CE2 3.67Å; L390-F473 HydrophobicContact CB-CZ 3.95Å; L390-F473 HydrophobicContact CD1-CE2 4.17Å; L390-F473 HydrophobicContact CD2-CE2 4.32Å; L390-F473 HydrophobicContact CG-CE2 4.29Å; I391-F473 HydrophobicContact CG1-CE1 4.4Å; I391-F473 HydrophobicContact CG1-CZ 4.26Å; V394-F473 HydrophobicContact CG2-CD1 3.98Å; V394-F473 HydrophobicContact CG2-CD2 4.29Å; V394-F473 HydrophobicContact CG2-CE1 4.05Å; V394-F473 HydrophobicContact CG2-CE2 4.37Å; V394-F473 HydrophobicContact CG2-CG 4.1Å; V394-F473 HydrophobicContact CG2-CZ 4.23Å; E469-F473 VanDerWaalsContact O-CB 3.25Å; E469-F473 WeakPolarHBondContact O-CB 3.36Å; E469-F473 PolarHBondContact O-N 3.01Å; V470-F473 PolarHBondContact O-N 3.23Å; F473-E476 PolarHBondContact O-N 3.22Å; F473-R477 VanDerWaalsContact O-CB 3.26Å; F473-R477 WeakPolarHBondContact O-CB 3.42Å; F473-R477 PolarHBondContact O-N 3.49Å
474	E	95.4	Very high	95.7	Very high	38 Å²	38	64 Å²	64	18%	0.178	29%	0.294	C	S	.	.	H	α-helix	trans	-64.6	-41.6	179.4	-73.3	-179.4	148.6	0	0	112	K300 H303 F304 V470 S471 R472 R477 V478	K300-E474 IonicContact NZ-OE1 3.92Å; K300-E474 PolarHBondContact NZ-OE1 2.9Å; K300-E474 IonicContact NZ-OE2 2.99Å; K300-E474 PolarHBondContact NZ-OE2 3.27Å; H303-E474 IonicContact CD2-OE1 2.67Å; F304-E474 HydrophobicContact CZ-CG 4.25Å; V470-E474 HydrophobicContact CG1-CG 4.42Å; V470-E474 WeakPolarHBondContact O-CG 3.43Å; V470-E474 PolarHBondContact O-N 3.07Å; S471-E474 PolarHBondContact O-N 3.31Å; R472-E474 VanDerWaalsContact C-N 3.35Å; R472-E474 PolarHBondContact O-N 3.15Å; E474-R477 PolarHBondContact O-N 2.87Å; E474-V478 WeakPolarHBondContact O-CG2 3.37Å; E474-V478 PolarHBondContact O-N 3.43Å
475	K	94.8	Very high	95.6	Very high	123 Å²	123	62.2 Å²	62.2	54%	0.535	29%	0.289	S	S	.	.	H	α-helix	trans	-61.4	-49	174.8	-70.8	-179.2	-178.9	-170.6	0	111.6	S471 R472 R477 V478 K479	S471-K475 WeakPolarHBondContact O-CG 3.39Å; S471-K475 PolarHBondContact O-N 3.25Å; S471-K475 VanDerWaalsContact O-N 3.17Å; R472-K475 PolarHBondContact O-N 3.42Å; K475-R477 PolarHBondContact O-N 2.92Å; K475-V478 PolarHBondContact O-N 3.43Å; K475-K479 PolarHBondContact O-N 2.89Å; K475-K479 VanDerWaalsContact O-N 3.13Å
476	E	92.6	Very high	95.6	Very high	52 Å²	52	65 Å²	65	24%	0.243	31%	0.306	C	S	.	.	H	α-helix	trans	-62.5	-42	178	-73	-178.1	179.7	0	0	111.8	R472 F473 V478 K479 D480	R472-E476 HydrophobicContact CG-CG 4.47Å; R472-E476 IonicContact CZ-OE1 3.1Å; R472-E476 IonicContact CZ-OE2 3.81Å; R472-E476 IonicContact NE-OE1 2.76Å; R472-E476 PolarHBondContact NE-OE1 3.03Å; R472-E476 IonicContact NE-OE2 2.96Å; R472-E476 VanDerWaalsContact NH2-CD 3.28Å; R472-E476 IonicContact NH2-OE1 3.86Å; R472-E476 PolarHBondContact NH2-OE1 2.88Å; R472-E476 IonicContact NH2-OE2 3.14Å; R472-E476 PolarHBondContact NH2-OE2 3.32Å; R472-E476 WeakPolarHBondContact O-CG 3.49Å; R472-E476 PolarHBondContact O-N 3.11Å; F473-E476 PolarHBondContact O-N 3.22Å; E476-V478 PolarHBondContact O-N 2.89Å; E476-K479 PolarHBondContact O-N 3.45Å; E476-D480 WeakPolarHBondContact O-CB 3.41Å; E476-D480 PolarHBondContact O-N 3.39Å
477	R	94.8	Very high	95.5	Very high	40 Å²	40	70.5 Å²	70.5	15%	0.151	33%	0.33	C	S	.	.	H	α-helix	trans	-54.3	-55.3	175.2	-176.4	-169.7	74.3	-167.2	-0.3	111.4	Y387 F473 E474 K475 K479 D480 F481	Y387-R477 HydrophobicContact CD1-CB 4.27Å; Y387-R477 HydrophobicContact CD1-CG 3.75Å; Y387-R477 HydrophobicContact CE1-CB 3.55Å; Y387-R477 HydrophobicContact CE1-CG 3.49Å; Y387-R477 VanDerWaalsContact CE1-CG 3.49Å; Y387-R477 VanDerWaalsContact OH-CA 3.32Å; Y387-R477 WeakPolarHBondContact OH-CA 3.43Å; F473-R477 VanDerWaalsContact O-CB 3.26Å; F473-R477 WeakPolarHBondContact O-CB 3.42Å; F473-R477 PolarHBondContact O-N 3.49Å; E474-R477 PolarHBondContact O-N 2.87Å; K475-R477 PolarHBondContact O-N 2.92Å; R477-K479 VanDerWaalsContact C-N 3.29Å; R477-K479 PolarHBondContact O-N 3.17Å; R477-D480 PolarHBondContact O-N 3.06Å; R477-F481 HydrophobicContact CG-CD2 3.63Å; R477-F481 HydrophobicContact CG-CE2 3.72Å; R477-F481 WeakPolarHBondContact O-CB 3.45Å; R477-F481 VanDerWaalsContact O-CD2 3.28Å; R477-F481 WeakPolarHBondContact O-CD2 3.48Å; R477-F481 PolarHBondContact O-N 3.38Å
478	V	95.7	Very high	95.4	Very high	82 Å²	82	66.3 Å²	66.3	50%	0.497	31%	0.314	S	S	.	.	H	α-helix	trans	-60.4	-42.9	-177.4	173.3	0	0	0	0	110.9	E474 K475 E476 K482	E474-V478 WeakPolarHBondContact O-CG2 3.37Å; E474-V478 PolarHBondContact O-N 3.43Å; K475-V478 PolarHBondContact O-N 3.43Å; E476-V478 PolarHBondContact O-N 2.89Å; V478-K482 VanDerWaalsContact O-CB 3.28Å; V478-K482 WeakPolarHBondContact O-CB 3.29Å; V478-K482 PolarHBondContact O-N 3.36Å
479	K	94	Very high	95.4	Very high	145 Å²	145	63.1 Å²	63.1	63%	0.63	30%	0.304	S	S	*	.	H	α-helix	trans	-61.1	-49.6	178	-175.8	172.8	-178.5	167.2	0	112.3	K475 E476 R477 K482 M483	K475-K479 PolarHBondContact O-N 2.89Å; K475-K479 VanDerWaalsContact O-N 3.13Å; E476-K479 PolarHBondContact O-N 3.45Å; R477-K479 VanDerWaalsContact C-N 3.29Å; R477-K479 PolarHBondContact O-N 3.17Å; K479-K482 PolarHBondContact O-N 3.24Å; K479-M483 WeakPolarHBondContact O-CB 3.46Å; K479-M483 PolarHBondContact O-N 3.38Å
480	D	92.6	Very high	95.4	Very high	24 Å²	24	67.5 Å²	67.5	13%	0.128	33%	0.325	C	S	.	.	H	α-helix	trans	-63.3	-47.1	-179.7	-78.1	-4.3	0	0	0	111.5	Y387 E476 R477 M483 I484	Y387-D480 HydrophobicContact CE2-CB 3.99Å; Y387-D480 WeakPolarHBondContact OH-CB 3.36Å; Y387-D480 PolarHBondContact OH-OD2 3.48Å; E476-D480 WeakPolarHBondContact O-CB 3.41Å; E476-D480 PolarHBondContact O-N 3.39Å; R477-D480 PolarHBondContact O-N 3.06Å; D480-M483 PolarHBondContact O-N 3.03Å; D480-I484 WeakPolarHBondContact O-CB 3.25Å; D480-I484 WeakPolarHBondContact O-CG1 3.31Å; D480-I484 PolarHBondContact O-N 3.44Å
481	F	95.3	Very high	95.3	Very high	32 Å²	32	68.9 Å²	68.9	14%	0.14	33%	0.334	C	S	.	.	H	α-helix	trans	-62.1	-45.5	178.5	-90.1	-86.9	0	0	0	111.7	L311 L383 L384 Y387 R477 M483 I484 I485	L311-F481 HydrophobicContact CD2-CE1 4.37Å; L311-F481 HydrophobicContact CD2-CZ 3.99Å; L383-F481 HydrophobicContact CD2-CD1 3.81Å; L383-F481 HydrophobicContact CD2-CE1 3.95Å; L383-F481 HydrophobicContact CD2-CG 4.19Å; L383-F481 HydrophobicContact CD2-CZ 4.46Å; L383-F481 HydrophobicContact CG-CE1 4.47Å; L384-F481 HydrophobicContact CD2-CE1 3.82Å; L384-F481 HydrophobicContact CD2-CZ 4.19Å; Y387-F481 AromaticContact CD1-CE2 3.87Å; Y387-F481 HydrophobicContact CD1-CE2 3.87Å; Y387-F481 HydrophobicContact CD2-CD2 4.08Å; Y387-F481 AromaticContact CD2-CE2 3.38Å; Y387-F481 HydrophobicContact CD2-CE2 3.38Å; Y387-F481 AromaticContact CD2-CZ 3.95Å; Y387-F481 HydrophobicContact CD2-CZ 3.95Å; Y387-F481 HydrophobicContact CE1-CE2 4.3Å; Y387-F481 HydrophobicContact CE2-CD2 4.1Å; Y387-F481 AromaticContact CE2-CE2 3.86Å; Y387-F481 HydrophobicContact CE2-CE2 3.86Å; Y387-F481 HydrophobicContact CG-CD2 4.37Å; Y387-F481 AromaticContact CG-CE2 3.4Å; Y387-F481 HydrophobicContact CG-CE2 3.4Å; Y387-F481 AromaticContact CG-CZ 3.98Å; Y387-F481 HydrophobicContact CG-CZ 3.98Å; R477-F481 HydrophobicContact CG-CD2 3.63Å; R477-F481 HydrophobicContact CG-CE2 3.72Å; R477-F481 WeakPolarHBondContact O-CB 3.45Å; R477-F481 VanDerWaalsContact O-CD2 3.28Å; R477-F481 WeakPolarHBondContact O-CD2 3.48Å; R477-F481 PolarHBondContact O-N 3.38Å; F481-M483 PolarHBondContact O-N 3.24Å; F481-I484 PolarHBondContact O-N 3.44Å; F481-I485 HydrophobicContact CB-CD1 4.39Å; F481-I485 HydrophobicContact CD1-CD1 4.21Å; F481-I485 VanDerWaalsContact O-CB 3.25Å; F481-I485 WeakPolarHBondContact O-CB 3.31Å; F481-I485 WeakPolarHBondContact O-CD1 3.35Å; F481-I485 WeakPolarHBondContact O-CG1 3.42Å; F481-I485 PolarHBondContact O-N 3.42Å
482	K	96.3	Very high	95.2	Very high	155 Å²	155	68.4 Å²	68.4	67%	0.674	33%	0.327	S	S	*	.	H	α-helix	trans	-57.9	-50.7	177.6	-176.8	-179.4	177.8	179.8	0	111	V478 K479 I484 V486	V478-K482 VanDerWaalsContact O-CB 3.28Å; V478-K482 WeakPolarHBondContact O-CB 3.29Å; V478-K482 PolarHBondContact O-N 3.36Å; K479-K482 PolarHBondContact O-N 3.24Å; K482-I484 PolarHBondContact O-N 2.91Å; K482-V486 VanDerWaalsContact O-CG2 3.25Å; K482-V486 WeakPolarHBondContact O-CG2 3.32Å; K482-V486 PolarHBondContact O-N 2.95Å; K482-V486 VanDerWaalsContact O-N 3.09Å
483	M	94.6	Very high	95.3	Very high	115 Å²	115	69.8 Å²	69.8	57%	0.567	34%	0.341	S	S	*	.	H	α-helix	trans	-59.1	-47.9	-179.1	179.8	-174.3	66.4	0	0	111.9	K479 D480 F481 K487	K479-M483 WeakPolarHBondContact O-CB 3.46Å; K479-M483 PolarHBondContact O-N 3.38Å; D480-M483 PolarHBondContact O-N 3.03Å; F481-M483 PolarHBondContact O-N 3.24Å; M483-K487 PolarHBondContact O-N 3.44Å; M483-K487 VanDerWaalsContact O-N 3.15Å
484	I	93.3	Very high	95.3	Very high	29 Å²	29	75.1 Å²	75.1	15%	0.149	37%	0.366	C	S	.	.	H	α-helix	trans	-74.4	-38.3	-175.7	-64.4	-64.6	0	0	0	112.1	L379 L383 D480 F481 K482 V486 K487 Y488	L379-I484 HydrophobicContact CB-CG2 4.26Å; L379-I484 WeakPolarHBondContact O-CG2 3.39Å; L383-I484 HydrophobicContact CB-CG2 4.45Å; L383-I484 HydrophobicContact CD1-CG1 4.32Å; L383-I484 HydrophobicContact CD2-CB 3.79Å; L383-I484 HydrophobicContact CD2-CG1 4.23Å; L383-I484 HydrophobicContact CD2-CG2 3.72Å; D480-I484 WeakPolarHBondContact O-CB 3.25Å; D480-I484 WeakPolarHBondContact O-CG1 3.31Å; D480-I484 PolarHBondContact O-N 3.44Å; F481-I484 PolarHBondContact O-N 3.44Å; K482-I484 PolarHBondContact O-N 2.91Å; I484-V486 VanDerWaalsContact C-N 3.33Å; I484-V486 PolarHBondContact O-N 2.84Å; I484-K487 PolarHBondContact O-N 3.21Å; I484-Y488 VanDerWaalsContact O-CB 3.25Å; I484-Y488 WeakPolarHBondContact O-CB 3.26Å; I484-Y488 PolarHBondContact O-N 2.99Å
485	I	95	Very high	95.4	Very high	66 Å²	66	74 Å²	74	34%	0.338	36%	0.362	S	S	.	.	H	α-helix	trans	-62.1	-43.3	176.2	-71.7	169	0	0	0	110.3	F481 Y488 L489	F481-I485 HydrophobicContact CB-CD1 4.39Å; F481-I485 HydrophobicContact CD1-CD1 4.21Å; F481-I485 VanDerWaalsContact O-CB 3.25Å; F481-I485 WeakPolarHBondContact O-CB 3.31Å; F481-I485 WeakPolarHBondContact O-CD1 3.35Å; F481-I485 WeakPolarHBondContact O-CG1 3.42Å; F481-I485 PolarHBondContact O-N 3.42Å; I485-Y488 PolarHBondContact O-N 3.2Å; I485-L489 HydrophobicContact CG2-CD1 3.83Å; I485-L489 HydrophobicContact CG2-CG 4.23Å; I485-L489 WeakPolarHBondContact O-CB 3.46Å; I485-L489 VanDerWaalsContact O-CG 3.28Å; I485-L489 WeakPolarHBondContact O-CG 3.41Å; I485-L489 PolarHBondContact O-N 2.85Å
486	V	96.8	Very high	95.4	Very high	69 Å²	69	73 Å²	73	42%	0.418	36%	0.359	S	S	.	.	H	α-helix	trans	-59	-52.3	175.9	170	0	0	0	0	110.3	K482 I484 Y488 L489 E490	K482-V486 VanDerWaalsContact O-CG2 3.25Å; K482-V486 WeakPolarHBondContact O-CG2 3.32Å; K482-V486 PolarHBondContact O-N 2.95Å; K482-V486 VanDerWaalsContact O-N 3.09Å; I484-V486 VanDerWaalsContact C-N 3.33Å; I484-V486 PolarHBondContact O-N 2.84Å; V486-Y488 VanDerWaalsContact C-N 3.26Å; V486-Y488 PolarHBondContact O-N 3.37Å; V486-L489 PolarHBondContact O-N 2.79Å; V486-E490 HydrophobicContact CG1-CG 4.39Å; V486-E490 WeakPolarHBondContact O-CG 3.26Å; V486-E490 PolarHBondContact O-N 3.26Å
487	K	96.1	Very high	95.7	Very high	114 Å²	114	75.5 Å²	75.5	50%	0.496	37%	0.371	S	S	.	.	H	α-helix	trans	-58.2	-39.3	178.7	-174.1	177.8	178.9	-179.9	0	112.6	L379 M483 I484 S491	L379-K487 HydrophobicContact CD1-CD 4.4Å; L379-K487 HydrophobicContact CD1-CG 4.18Å; L379-K487 HydrophobicContact CD2-CD 4.12Å; M483-K487 PolarHBondContact O-N 3.44Å; M483-K487 VanDerWaalsContact O-N 3.15Å; I484-K487 PolarHBondContact O-N 3.21Å; K487-S491 PolarHBondContact O-N 2.99Å
488	Y	95.9	Very high	95.8	Very high	20 Å²	20	76.3 Å²	76.3	8%	0.078	38%	0.376	C	S	.	.	H	α-helix	trans	-66.7	-46.9	177.8	173.8	-111.4	0	0	0	111.7	D376 F380 I484 I485 V486 E490 S491 L492	D376-Y488 WeakPolarHBondContact OD1-CE2 3.44Å; D376-Y488 PolarHBondContact OD1-OH 3.01Å; F380-Y488 HydrophobicContact CB-CD2 4.27Å; F380-Y488 HydrophobicContact CB-CE2 4.35Å; F380-Y488 HydrophobicContact CB-CG 4.44Å; F380-Y488 HydrophobicContact CD1-CD1 4.36Å; F380-Y488 AromaticContact CD1-CE1 3.93Å; F380-Y488 HydrophobicContact CD1-CE1 3.93Å; F380-Y488 HydrophobicContact CE1-CE1 4.36Å; I484-Y488 VanDerWaalsContact O-CB 3.25Å; I484-Y488 WeakPolarHBondContact O-CB 3.26Å; I484-Y488 PolarHBondContact O-N 2.99Å; I485-Y488 PolarHBondContact O-N 3.2Å; V486-Y488 VanDerWaalsContact C-N 3.26Å; V486-Y488 PolarHBondContact O-N 3.37Å; Y488-E490 VanDerWaalsContact C-N 3.35Å; Y488-E490 PolarHBondContact O-N 3.46Å; Y488-S491 WeakPolarHBondContact O-CB 3.36Å; Y488-S491 PolarHBondContact O-N 3.35Å; Y488-L492 HydrophobicContact CD1-CD1 4.21Å; Y488-L492 HydrophobicContact CE1-CD1 3.63Å; Y488-L492 HydrophobicContact CE1-CG 4.33Å; Y488-L492 HydrophobicContact CE2-CD1 4.4Å; Y488-L492 HydrophobicContact CE2-CD2 4.28Å; Y488-L492 HydrophobicContact CE2-CG 4.28Å; Y488-L492 WeakPolarHBondContact O-CG 3.43Å; Y488-L492 PolarHBondContact O-N 2.99Å
489	L	96.7	Very high	95.9	Very high	93 Å²	93	74 Å²	74	49%	0.487	36%	0.361	S	S	.	.	H	α-helix	trans	-63.2	-40	176.7	-69.7	173.8	0	0	0	112.1	I485 V486 S491 L492 V493	I485-L489 HydrophobicContact CG2-CD1 3.83Å; I485-L489 HydrophobicContact CG2-CG 4.23Å; I485-L489 WeakPolarHBondContact O-CB 3.46Å; I485-L489 VanDerWaalsContact O-CG 3.28Å; I485-L489 WeakPolarHBondContact O-CG 3.41Å; I485-L489 PolarHBondContact O-N 2.85Å; V486-L489 PolarHBondContact O-N 2.79Å; L489-S491 VanDerWaalsContact C-N 3.32Å; L489-S491 PolarHBondContact O-N 3.49Å; L489-L492 HydrophobicContact CD2-CD1 4.32Å; L489-L492 PolarHBondContact O-N 2.96Å; L489-V493 WeakPolarHBondContact O-CG2 3.47Å; L489-V493 PolarHBondContact O-N 3.37Å
490	E	96.8	Very high	96.1	Very high	105 Å²	105	70.9 Å²	70.9	49%	0.491	35%	0.35	S	S	.	.	H	α-helix	trans	-59	-44.2	173.2	-73.1	171.3	164.5	0	0	111.4	V486 Y488 L492 V493 Q494	V486-E490 HydrophobicContact CG1-CG 4.39Å; V486-E490 WeakPolarHBondContact O-CG 3.26Å; V486-E490 PolarHBondContact O-N 3.26Å; Y488-E490 VanDerWaalsContact C-N 3.35Å; Y488-E490 PolarHBondContact O-N 3.46Å; E490-L492 VanDerWaalsContact C-N 3.35Å; E490-L492 PolarHBondContact O-N 3.37Å; E490-V493 PolarHBondContact O-N 3.24Å; E490-Q494 WeakPolarHBondContact O-CB 3.44Å; E490-Q494 VanDerWaalsContact O-CG 3.25Å; E490-Q494 WeakPolarHBondContact O-CG 3.19Å; E490-Q494 PolarHBondContact O-N 3.34Å
491	S	96.3	Very high	96.3	Very high	28 Å²	28	75.1 Å²	75.1	20%	0.196	37%	0.368	C	S	.	.	H	α-helix	trans	-59.3	-44.4	174.8	-170.4	0	0	0	0	111.7	K487 Y488 L489 V493 Q494 T495	K487-S491 PolarHBondContact O-N 2.99Å; Y488-S491 WeakPolarHBondContact O-CB 3.36Å; Y488-S491 PolarHBondContact O-N 3.35Å; L489-S491 VanDerWaalsContact C-N 3.32Å; L489-S491 PolarHBondContact O-N 3.49Å; S491-V493 PolarHBondContact O-N 3.46Å; S491-Q494 PolarHBondContact O-N 3.25Å; S491-T495 PolarHBondContact O-N 3.19Å; S491-T495 PolarHBondContact O-OG1 3.41Å; S491-T495 VanDerWaalsContact O-OG1 3.05Å
492	L	95.6	Very high	96.4	Very high	45 Å²	45	76.1 Å²	76.1	24%	0.236	37%	0.371	C	S	.	.	H	α-helix	trans	-62.4	-43	178	-67.7	178.8	0	0	0	112.3	Q372 Y488 L489 E490 T495 Q496	Q372-L492 HydrophobicContact CG-CD2 3.92Å; Y488-L492 HydrophobicContact CD1-CD1 4.21Å; Y488-L492 HydrophobicContact CE1-CD1 3.63Å; Y488-L492 HydrophobicContact CE1-CG 4.33Å; Y488-L492 HydrophobicContact CE2-CD1 4.4Å; Y488-L492 HydrophobicContact CE2-CD2 4.28Å; Y488-L492 HydrophobicContact CE2-CG 4.28Å; Y488-L492 WeakPolarHBondContact O-CG 3.43Å; Y488-L492 PolarHBondContact O-N 2.99Å; L489-L492 HydrophobicContact CD2-CD1 4.32Å; L489-L492 PolarHBondContact O-N 2.96Å; E490-L492 VanDerWaalsContact C-N 3.35Å; E490-L492 PolarHBondContact O-N 3.37Å; L492-T495 PolarHBondContact O-N 3.03Å; L492-Q496 WeakPolarHBondContact O-CB 3.46Å; L492-Q496 PolarHBondContact O-N 3Å
493	V	97.3	Very high	96.5	Very high	80 Å²	80	73.6 Å²	73.6	49%	0.485	36%	0.357	S	S	.	.	H	α-helix	trans	-63.2	-43.7	177.3	171	0	0	0	0	110.7	L489 E490 S491 Q496 Q497	L489-V493 WeakPolarHBondContact O-CG2 3.47Å; L489-V493 PolarHBondContact O-N 3.37Å; E490-V493 PolarHBondContact O-N 3.24Å; S491-V493 PolarHBondContact O-N 3.46Å; V493-Q496 PolarHBondContact O-N 3.35Å; V493-Q497 HydrophobicContact CG1-CG 4.37Å; V493-Q497 WeakPolarHBondContact O-CB 3.48Å; V493-Q497 VanDerWaalsContact O-CG 3.31Å; V493-Q497 WeakPolarHBondContact O-CG 3.35Å; V493-Q497 PolarHBondContact O-N 2.89Å
494	Q	96.4	Very high	96.6	Very high	123 Å²	123	74.1 Å²	74.1	58%	0.575	36%	0.358	S	S	*	.	H	α-helix	trans	-61.5	-46.5	178	-72.6	170.3	8.6	0	0	111.7	E490 S491 Q496 Q497 Q498	E490-Q494 WeakPolarHBondContact O-CB 3.44Å; E490-Q494 VanDerWaalsContact O-CG 3.25Å; E490-Q494 WeakPolarHBondContact O-CG 3.19Å; E490-Q494 PolarHBondContact O-N 3.34Å; S491-Q494 PolarHBondContact O-N 3.25Å; Q494-Q496 VanDerWaalsContact C-N 3.33Å; Q494-Q496 PolarHBondContact O-N 3.38Å; Q494-Q497 PolarHBondContact O-N 3.35Å; Q494-Q498 PolarHBondContact O-N 2.93Å
495	T	95.8	Very high	96.7	Very high	15 Å²	15	76.1 Å²	76.1	9%	0.092	38%	0.379	C	S	.	.	H	α-helix	trans	-58.4	-45.8	175.6	-58	0	0	0	0	111.1	L368 Q372 S491 L492 Q497 Q498 L499	L368-T495 HydrophobicContact CB-CG2 4.01Å; L368-T495 HydrophobicContact CD2-CG2 4.29Å; Q372-T495 HydrophobicContact CB-CG2 4.38Å; S491-T495 PolarHBondContact O-N 3.19Å; S491-T495 PolarHBondContact O-OG1 3.41Å; S491-T495 VanDerWaalsContact O-OG1 3.05Å; L492-T495 PolarHBondContact O-N 3.03Å; T495-Q497 PolarHBondContact O-N 3.31Å; T495-Q498 PolarHBondContact O-N 3.39Å; T495-L499 PolarHBondContact O-N 3.3Å
496	Q	96.7	Very high	96.7	Very high	100 Å²	100	74.1 Å²	74.1	47%	0.467	37%	0.368	S	S	.	.	H	α-helix	trans	-66	-40.1	-179.4	-169.8	62	17.7	0	0	112.7	L492 V493 Q494 Q498 L499 I500	L492-Q496 WeakPolarHBondContact O-CB 3.46Å; L492-Q496 PolarHBondContact O-N 3Å; V493-Q496 PolarHBondContact O-N 3.35Å; Q494-Q496 VanDerWaalsContact C-N 3.33Å; Q494-Q496 PolarHBondContact O-N 3.38Å; Q496-Q498 VanDerWaalsContact C-N 3.27Å; Q496-Q498 PolarHBondContact O-N 3.07Å; Q496-L499 PolarHBondContact O-N 2.96Å; Q496-I500 HydrophobicContact CG-CD1 4.49Å; Q496-I500 WeakPolarHBondContact O-CG1 3.46Å; Q496-I500 PolarHBondContact O-N 3.01Å
497	Q	97.9	Very high	96.6	Very high	105 Å²	105	75 Å²	75	49%	0.491	37%	0.37	S	S	.	.	H	α-helix	trans	-61.9	-38.1	174.6	-75.2	175.3	-7.9	0	0	111.7	V493 Q494 T495 K501	V493-Q497 HydrophobicContact CG1-CG 4.37Å; V493-Q497 WeakPolarHBondContact O-CB 3.48Å; V493-Q497 VanDerWaalsContact O-CG 3.31Å; V493-Q497 WeakPolarHBondContact O-CG 3.35Å; V493-Q497 PolarHBondContact O-N 2.89Å; Q494-Q497 PolarHBondContact O-N 3.35Å; T495-Q497 PolarHBondContact O-N 3.31Å; Q497-K501 WeakPolarHBondContact O-CG 3.48Å; Q497-K501 PolarHBondContact O-N 2.83Å
498	Q	97.8	Very high	96.3	Very high	58 Å²	58	73.4 Å²	73.4	27%	0.271	37%	0.372	S	S	.	.	H	α-helix	trans	-70.5	-39.6	178.4	-164.3	61.7	24.3	0	0	111.8	L368 Q494 T495 Q496 I500 K501 Y502	L368-Q498 HydrophobicContact CD1-CB 3.99Å; L368-Q498 HydrophobicContact CD1-CG 4.09Å; L368-Q498 HydrophobicContact CD2-CB 4.07Å; L368-Q498 HydrophobicContact CD2-CG 3.99Å; Q494-Q498 PolarHBondContact O-N 2.93Å; T495-Q498 PolarHBondContact O-N 3.39Å; Q496-Q498 VanDerWaalsContact C-N 3.27Å; Q496-Q498 PolarHBondContact O-N 3.07Å; Q498-I500 VanDerWaalsContact C-N 3.35Å; Q498-I500 PolarHBondContact O-N 2.82Å; Q498-K501 PolarHBondContact O-N 3.14Å; Q498-Y502 HydrophobicContact CG-CE1 4.04Å; Q498-Y502 HydrophobicContact CG-CE2 3.8Å; Q498-Y502 WeakPolarHBondContact CG-OH 3.3Å; Q498-Y502 VanDerWaalsContact NE2-CZ 3.26Å; Q498-Y502 PolarHBondContact NE2-OH 3.15Å; Q498-Y502 PolarHBondContact O-N 3.43Å; Q498-Y502 VanDerWaalsContact O-N 3.07Å
499	L	97.2	Very high	95.9	Very high	34 Å²	34	74.7 Å²	74.7	18%	0.178	38%	0.378	C	S	.	.	H	α-helix	trans	-57.7	-46.1	173.4	-179.1	62.6	0	0	0	111.7	I365 L368 T495 Q496 K501 Y502 W503	I365-L499 HydrophobicContact CB-CD1 4.41Å; I365-L499 HydrophobicContact CD1-CD1 3.65Å; I365-L499 HydrophobicContact CG1-CD1 3.56Å; I365-L499 HydrophobicContact CG2-CD1 4.04Å; L368-L499 HydrophobicContact CD1-CB 4.18Å; T495-L499 PolarHBondContact O-N 3.3Å; Q496-L499 PolarHBondContact O-N 2.96Å; L499-K501 VanDerWaalsContact C-N 3.34Å; L499-K501 PolarHBondContact O-N 3.22Å; L499-Y502 PolarHBondContact O-N 3.13Å; L499-W503 VanDerWaalsContact O-CD1 3.27Å; L499-W503 PolarHBondContact O-N 3.09Å; L499-W503 VanDerWaalsContact O-N 3.15Å
500	I	97.8	Very high	95.5	Very high	78 Å²	78	72 Å²	72	40%	0.4	37%	0.37	S	S	.	.	H	α-helix	trans	-57.7	-48.1	176.6	-69.1	165.1	0	0	0	110.6	Q496 Q498 Y502 W503 E504	Q496-I500 HydrophobicContact CG-CD1 4.49Å; Q496-I500 WeakPolarHBondContact O-CG1 3.46Å; Q496-I500 PolarHBondContact O-N 3.01Å; Q498-I500 VanDerWaalsContact C-N 3.35Å; Q498-I500 PolarHBondContact O-N 2.82Å; I500-Y502 VanDerWaalsContact C-N 3.28Å; I500-Y502 PolarHBondContact O-N 3.45Å; I500-W503 PolarHBondContact O-N 3.14Å; I500-E504 HydrophobicContact CG2-CG 4.09Å; I500-E504 WeakPolarHBondContact O-CB 3.5Å; I500-E504 WeakPolarHBondContact O-CG 3.33Å; I500-E504 PolarHBondContact O-N 3.5Å
501	K	97.8	Very high	95.1	Very high	114 Å²	114	73.2 Å²	73.2	50%	0.496	37%	0.373	S	S	.	.	H	α-helix	trans	-59.2	-38.7	179.3	-70.5	172.3	-172	170.5	0	112.6	Q497 Q498 L499 A505	Q497-K501 WeakPolarHBondContact O-CG 3.48Å; Q497-K501 PolarHBondContact O-N 2.83Å; Q498-K501 PolarHBondContact O-N 3.14Å; L499-K501 VanDerWaalsContact C-N 3.34Å; L499-K501 PolarHBondContact O-N 3.22Å; K501-A505 VanDerWaalsContact O-CB 3.29Å; K501-A505 WeakPolarHBondContact O-CB 3.41Å; K501-A505 PolarHBondContact O-N 3.46Å
502	Y	97.5	Very high	94.5	Very high	52 Å²	52	75 Å²	75	20%	0.204	39%	0.389	C	S	.	.	H	α-helix	trans	-65.5	-44.8	178	-64.3	-24.6	0	0	0	112	K364 I365 L368 Q498 L499 I500 A505 F506	K364-Y502 HydrophobicContact CB-CD2 3.85Å; K364-Y502 HydrophobicContact CB-CE1 4.4Å; K364-Y502 HydrophobicContact CB-CE2 3.53Å; K364-Y502 HydrophobicContact CB-CG 4.43Å; K364-Y502 HydrophobicContact CD-CD1 4.31Å; K364-Y502 HydrophobicContact CD-CE1 4.06Å; I365-Y502 HydrophobicContact CG1-CD2 4.27Å; L368-Y502 HydrophobicContact CD1-CD2 3.77Å; L368-Y502 HydrophobicContact CD1-CE2 3.45Å; L368-Y502 VanDerWaalsContact CD1-CE2 3.45Å; L368-Y502 HydrophobicContact CG-CE2 3.87Å; Q498-Y502 HydrophobicContact CG-CE1 4.04Å; Q498-Y502 HydrophobicContact CG-CE2 3.8Å; Q498-Y502 WeakPolarHBondContact CG-OH 3.3Å; Q498-Y502 VanDerWaalsContact NE2-CZ 3.26Å; Q498-Y502 PolarHBondContact NE2-OH 3.15Å; Q498-Y502 PolarHBondContact O-N 3.43Å; Q498-Y502 VanDerWaalsContact O-N 3.07Å; L499-Y502 PolarHBondContact O-N 3.13Å; I500-Y502 VanDerWaalsContact C-N 3.28Å; I500-Y502 PolarHBondContact O-N 3.45Å; Y502-A505 PolarHBondContact O-N 3.4Å; Y502-F506 PolarHBondContact O-N 3.35Å; Y502-F506 VanDerWaalsContact O-N 3.15Å
503	W	97.3	Very high	93.8	Very high	103 Å²	103	76.2 Å²	76.2	39%	0.39	40%	0.395	S	S	.	.	H	α-helix	trans	-67.9	-40.4	176.5	-74.9	112.9	0	0	0	113.1	L358 I365 L499 I500 A505 F506 L507	L358-W503 HydrophobicContact CD1-CH2 4.16Å; L358-W503 HydrophobicContact CD1-CZ3 4.14Å; I365-W503 HydrophobicContact CD1-CH2 4.49Å; I365-W503 HydrophobicContact CD1-CZ2 3.56Å; L499-W503 VanDerWaalsContact O-CD1 3.27Å; L499-W503 PolarHBondContact O-N 3.09Å; L499-W503 VanDerWaalsContact O-N 3.15Å; I500-W503 PolarHBondContact O-N 3.14Å; W503-A505 VanDerWaalsContact C-N 3.3Å; W503-A505 PolarHBondContact O-N 3.2Å; W503-F506 HydrophobicContact CE3-CD1 4.07Å; W503-F506 AromaticContact CZ3-CD1 3.96Å; W503-F506 HydrophobicContact CZ3-CD1 3.96Å; W503-F506 HydrophobicContact CZ3-CE1 4.37Å; W503-F506 PolarHBondContact O-N 3.12Å; W503-L507 PolarHBondContact O-N 2.66Å
504	E	96.7	Very high	91.9	Very high	125 Å²	125	79.5 Å²	79.5	58%	0.584	42%	0.422	S	S	*	.	H	α-helix	trans	-62.3	-38.3	175.6	-74.6	179.1	158.3	0	0	112	I500 F506 P508	I500-E504 HydrophobicContact CG2-CG 4.09Å; I500-E504 WeakPolarHBondContact O-CB 3.5Å; I500-E504 WeakPolarHBondContact O-CG 3.33Å; I500-E504 PolarHBondContact O-N 3.5Å; E504-F506 VanDerWaalsContact C-N 3.32Å; E504-P508 WeakPolarHBondContact O-CD 3.41Å
505	A	95.4	Very high	91.7	Very high	72 Å²	72	77.4 Å²	77.4	60%	0.595	42%	0.415	S	S	*	.	H	α-helix	trans	-67.5	-32.4	175.9	0	0	0	0	0	112.6	K501 Y502 W503 P508	K501-A505 VanDerWaalsContact O-CB 3.29Å; K501-A505 WeakPolarHBondContact O-CB 3.41Å; K501-A505 PolarHBondContact O-N 3.46Å; Y502-A505 PolarHBondContact O-N 3.4Å; W503-A505 VanDerWaalsContact C-N 3.3Å; W503-A505 PolarHBondContact O-N 3.2Å; A505-P508 WeakPolarHBondContact O-CD 3.41Å
506	F	95.3	Very high	91.5	Very high	23 Å²	23	80.6 Å²	80.6	10%	0.101	43%	0.432	C	S	.	.	H	α-helix	trans	-78.2	-30.9	178	-179.2	-118	0	0	0	113.6	Q357 L358 V361 Y502 W503 E504 P508 E509 A510	Q357-F506 HydrophobicContact CB-CD2 4.2Å; Q357-F506 HydrophobicContact CB-CE2 4.1Å; L358-F506 HydrophobicContact CB-CE1 4.5Å; L358-F506 HydrophobicContact CB-CE2 3.94Å; L358-F506 HydrophobicContact CB-CZ 3.75Å; L358-F506 HydrophobicContact CD1-CD1 4.49Å; L358-F506 HydrophobicContact CD1-CE1 3.9Å; L358-F506 HydrophobicContact CD1-CZ 4.01Å; L358-F506 HydrophobicContact CG-CZ 4.38Å; V361-F506 HydrophobicContact CG2-CB 3.89Å; V361-F506 HydrophobicContact CG2-CD2 4.19Å; V361-F506 HydrophobicContact CG2-CG 4.19Å; Y502-F506 PolarHBondContact O-N 3.35Å; Y502-F506 VanDerWaalsContact O-N 3.15Å; W503-F506 HydrophobicContact CE3-CD1 4.07Å; W503-F506 AromaticContact CZ3-CD1 3.96Å; W503-F506 HydrophobicContact CZ3-CD1 3.96Å; W503-F506 HydrophobicContact CZ3-CE1 4.37Å; W503-F506 PolarHBondContact O-N 3.12Å; E504-F506 VanDerWaalsContact C-N 3.32Å; F506-P508 VanDerWaalsContact O-N 3.17Å; F506-E509 PolarHBondContact O-N 2.99Å; F506-A510 HydrophobicContact CD1-CB 4.41Å; F506-A510 HydrophobicContact CE1-CB 3.93Å; F506-A510 HydrophobicContact CZ-CB 4.21Å; F506-A510 PolarHBondContact O-N 3.44Å
507	L	93.6	Very high	91.2	Very high	88 Å²	88	79.6 Å²	79.6	46%	0.461	43%	0.43	S	S	.	.	H	α-helix	trans	-50.9	-41	-172.4	-174.1	66.6	0	0	0	115.5	W503 E509 K511	W503-L507 PolarHBondContact O-N 2.66Å; L507-E509 VanDerWaalsContact C-N 3.3Å; L507-E509 PolarHBondContact O-N 3.47Å; L507-K511 HydrophobicContact CG-CD 4.5Å; L507-K511 WeakPolarHBondContact O-CG 3.38Å; L507-K511 PolarHBondContact O-N 3.29Å; L507-K511 VanDerWaalsContact O-N 3.15Å
508	P	91.3	Very high	90.8	Very high	81 Å²	81	78.1 Å²	78.1	53%	0.526	43%	0.426	S	S	.	.	H	α-helix	trans	-62.6	-36.1	177.7	-22.3	34.7	0	0	0	113.3	E504 A505 F506 K511 A512	E504-P508 WeakPolarHBondContact O-CD 3.41Å; A505-P508 WeakPolarHBondContact O-CD 3.41Å; F506-P508 VanDerWaalsContact O-N 3.17Å; P508-K511 PolarHBondContact O-N 2.86Å; P508-A512 PolarHBondContact O-N 2.92Å; P508-A512 VanDerWaalsContact O-N 3.13Å
509	E	87.8	Confident	90.4	Very high	47 Å²	47	79.3 Å²	79.3	22%	0.22	44%	0.436	C	S	.	.	H	α-helix	trans	-77.2	-34.8	-176.3	-67.5	-98.8	-157.9	0	0	110.3	R353 Q357 F506 L507 K511 A512	R353-E509 IonicContact CZ-OE1 3.49Å; R353-E509 IonicContact NE-OE1 3.26Å; R353-E509 PolarHBondContact NE-OE1 3.07Å; R353-E509 IonicContact NE-OE2 3.14Å; R353-E509 PolarHBondContact NE-OE2 2.95Å; R353-E509 VanDerWaalsContact NE-OE2 3.14Å; R353-E509 IonicContact NH2-OE1 2.84Å; R353-E509 PolarHBondContact NH2-OE1 3.44Å; Q357-E509 PolarHBondContact NE2-OE1 3.42Å; Q357-E509 PolarHBondContact NE2-OE2 3.11Å; Q357-E509 VanDerWaalsContact OE1-CD 3.28Å; Q357-E509 PolarHBondContact OE1-OE1 3.42Å; F506-E509 PolarHBondContact O-N 2.99Å; L507-E509 VanDerWaalsContact C-N 3.3Å; L507-E509 PolarHBondContact O-N 3.47Å; E509-K511 VanDerWaalsContact C-N 3.34Å; E509-K511 PolarHBondContact O-N 3.12Å; E509-A512 WeakPolarHBondContact O-CB 3.41Å; E509-A512 PolarHBondContact O-N 2.77Å
510	A	87.1	Confident	89.9	Confident	37 Å²	37	82.3 Å²	82.3	31%	0.306	45%	0.453	S	S	.	.	H	α-helix	trans	-61.1	-40.3	168.1	0	0	0	0	0	112.7	F506 A512 I513	F506-A510 HydrophobicContact CD1-CB 4.41Å; F506-A510 HydrophobicContact CE1-CB 3.93Å; F506-A510 HydrophobicContact CZ-CB 4.21Å; F506-A510 PolarHBondContact O-N 3.44Å; A510-A512 VanDerWaalsContact C-N 3.27Å; A510-A512 PolarHBondContact O-N 2.94Å; A510-I513 PolarHBondContact O-N 2.94Å
511	K	88.9	Confident	89.4	Confident	130 Å²	130	82.6 Å²	82.6	57%	0.565	46%	0.457	S	S	*	.	H	α-helix	trans	-71.1	-19.3	176.9	-72.2	177.8	178.7	176.3	0	113.7	L507 P508 E509 I513 S514	L507-K511 HydrophobicContact CG-CD 4.5Å; L507-K511 WeakPolarHBondContact O-CG 3.38Å; L507-K511 PolarHBondContact O-N 3.29Å; L507-K511 VanDerWaalsContact O-N 3.15Å; P508-K511 PolarHBondContact O-N 2.86Å; E509-K511 VanDerWaalsContact C-N 3.34Å; E509-K511 PolarHBondContact O-N 3.12Å; K511-I513 PolarHBondContact O-N 3.4Å; K511-S514 PolarHBondContact O-OG 3.35Å
512	A	83.3	Confident	88.7	Confident	65 Å²	65	80.2 Å²	80.2	54%	0.537	45%	0.454	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-10.9	178.7	0	0	0	0	0	113.1	P508 E509 A510	P508-A512 PolarHBondContact O-N 2.92Å; P508-A512 VanDerWaalsContact O-N 3.13Å; E509-A512 WeakPolarHBondContact O-CB 3.41Å; E509-A512 PolarHBondContact O-N 2.77Å; A510-A512 VanDerWaalsContact C-N 3.27Å; A510-A512 PolarHBondContact O-N 2.94Å
513	I	80.8	Confident	88	Confident	70 Å²	70	82.6 Å²	82.6	36%	0.359	47%	0.474	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.6	-28.6	178.8	-46.2	167.6	0	0	0	111.7	L351 A354 A510 K511	L351-I513 HydrophobicContact CB-CG2 4.49Å; L351-I513 HydrophobicContact CD1-CD1 4.19Å; L351-I513 HydrophobicContact CD1-CG2 4.01Å; A354-I513 HydrophobicContact CB-CD1 3.17Å; A354-I513 HydrophobicContact CB-CG1 3.7Å; A510-I513 PolarHBondContact O-N 2.94Å; K511-I513 PolarHBondContact O-N 3.4Å
514	S	58.4	Low	87.1	Confident	150 Å²	150	80.7 Å²	80.7	100%	1.049	48%	0.482	S	S	*	.			trans	-77	0	176.9	66.1	0	0	0	0	111.8	K511	K511-S514 PolarHBondContact O-OG 3.35Å

Retrieved 514 of 514 residues in 102.1 ms (Link to these results)

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