A0A087X4K5_POEFO Loading...

Cystine/glutamate transporter

AlphaFold DB , UniProt , Accession A0A087X4K5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 504 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	V	36.4	Very low	25.9	Very low	191 Å²	191	173 Å²	173	100%	1.158	88%	0.881	S	S	*	*				0	90.3	0	178.1	0	0	0	0	108.8
2	F	24.9	Very low	25.9	Very low	220 Å²	220	171.7 Å²	171.7	97%	0.965	88%	0.877	S	S	*	*			trans	-156.3	113.3	161.7	-104.4	-77.8	0	0	0	107
3	K	24.5	Very low	25.8	Very low	194 Å²	194	172.7 Å²	172.7	84%	0.843	87%	0.872	S	S	*	*			trans	-90.2	113.8	-167.7	-163.9	173.5	-177.1	177.4	0	108.5	M5	K3-M5 PolarHBondContact O-N 3.36Å
4	K	27.1	Very low	25.8	Very low	199 Å²	199	172.6 Å²	172.6	87%	0.865	88%	0.875	S	S	*	*			trans	-64.1	123.5	164.1	-101.9	177.3	173.3	176.9	0	108
5	M	25.3	Very low	25.6	Very low	177 Å²	177	165.8 Å²	165.8	87%	0.872	87%	0.865	S	S	*	*			trans	-108.7	96.5	172.6	-139.7	166.9	-171.1	0	0	108	K3	K3-M5 PolarHBondContact O-N 3.36Å
6	N	23.8	Very low	25.4	Very low	150 Å²	150	167.1 Å²	167.1	80%	0.802	87%	0.865	S	S	*	*			trans	-72.3	125.8	166.1	-84.6	-9.4	0	0	0	108.2
7	R	24.7	Very low	25.3	Very low	252 Å²	252	164.6 Å²	164.6	95%	0.951	86%	0.859	S	S	*	*			trans	-89.9	109.2	162.4	-89.8	-178.2	172.1	175.8	-2.6	108.2
8	S	23.9	Very low	25.2	Very low	116 Å²	116	160.9 Å²	160.9	81%	0.811	86%	0.857	S	S	*	*	P	Polyproline II helix	trans	-85.3	123.7	168.3	49.2	0	0	0	0	109.9
9	T	25	Very low	25	Very low	141 Å²	141	157.4 Å²	157.4	87%	0.865	85%	0.846	S	S	*	*	P	Polyproline II helix	trans	-86.5	120.9	166.4	7.2	0	0	0	0	109
10	S	24.6	Very low	24.9	Very low	112 Å²	112	157.8 Å²	157.8	78%	0.783	85%	0.848	S	S	*	*	P	Polyproline II helix	trans	-73.3	129.2	179.5	50.6	0	0	0	0	111.8
11	I	24.8	Very low	24.8	Very low	151 Å²	151	153.4 Å²	153.4	77%	0.774	84%	0.84	S	S	*	*	P	Polyproline II helix	trans	-90	121.1	168.6	-63.4	168.3	0	0	0	107.4
12	N	25.1	Very low	24.1	Very low	157 Å²	157	153.5 Å²	153.5	84%	0.84	83%	0.828	S	S	*	*	P	Polyproline II helix	trans	-96.7	120.8	162.7	-88.3	0.5	0	0	0	109.1
13	K	25	Very low	24	Very low	185 Å²	185	148.6 Å²	148.6	80%	0.804	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-94.7	136.4	160.4	-80	180	171.7	-178.7	0	107
14	D	25.9	Very low	23.9	Very low	172 Å²	172	148.7 Å²	148.7	92%	0.92	82%	0.817	S	S	*	*			trans	-151.8	139.9	146.6	-81.8	-37.8	0	0	0	107.7
15	G	22.8	Very low	23.7	Very low	70 Å²	70	144.1 Å²	144.1	72%	0.722	81%	0.81	S	S	*	*			trans	-120.5	175.4	-169.6	0	0	0	0	0	115
16	E	23.2	Very low	23.6	Very low	186 Å²	186	143.6 Å²	143.6	87%	0.869	81%	0.806	S	S	*	*			trans	70.2	134.2	161.5	-57.3	-171.9	154.7	0	0	116.9
17	T	23.6	Very low	23.6	Very low	125 Å²	125	144.2 Å²	144.2	77%	0.767	81%	0.809	S	S	*	*				-171.1	147.8	51.6	19	0	0	0	0	110.8
18	A	22.8	Very low	23.6	Very low	99 Å²	99	135.8 Å²	135.8	82%	0.818	80%	0.801	S	S	*	*			trans	41.4	149.2	134.8	0	0	0	0	0	121.1
19	S	21.5	Very low	23.7	Very low	93 Å²	93	140 Å²	140	65%	0.65	80%	0.804	S	S	*	*			cis	175.1	156.3	9.6	139.4	0	0	0	0	108.4
20	N	23.5	Very low	23.8	Very low	165 Å²	165	140.8 Å²	140.8	88%	0.882	80%	0.803	S	S	*	*			trans	70.7	135.7	163	-64.1	-18.3	0	0	0	118.6
21	G	21.7	Very low	24.1	Very low	66 Å²	66	144.5 Å²	144.5	68%	0.68	81%	0.813	S	S	*	*			cis	145.6	123.7	5.6	0	0	0	0	0	108.9
22	Q	23.4	Very low	24	Very low	194 Å²	194	140.5 Å²	140.5	91%	0.907	81%	0.81	S	S	*	*			trans	171.6	108.2	144.9	-96.2	176	-2.9	0	0	113.8
23	T	21.9	Very low	24.1	Very low	117 Å²	117	137 Å²	137	72%	0.718	81%	0.811	S	S	*	*				32.2	120.2	129.6	18	0	0	0	0	124.1
24	F	21.5	Very low	24.1	Very low	196 Å²	196	137.8 Å²	137.8	86%	0.86	81%	0.814	S	S	*	*				70.1	115	128.4	-96.4	-98.4	0	0	0	123.6
25	S	23	Very low	24.2	Very low	102 Å²	102	137.9 Å²	137.9	71%	0.713	81%	0.814	S	S	*	*				129.1	117.3	114.9	-159.1	0	0	0	0	117.1
26	Q	23.8	Very low	24.4	Very low	167 Å²	167	143.4 Å²	143.4	78%	0.78	82%	0.821	S	S	*	*			trans	-7.5	123.2	157.8	-70.5	173.8	-20	0	0	119.7
27	N	23.6	Very low	24.6	Very low	162 Å²	162	143.8 Å²	143.8	87%	0.866	82%	0.822	S	S	*	*				155.2	123.9	103.7	-93.4	-24	0	0	0	111
28	G	24.9	Very low	24.7	Very low	76 Å²	76	141.5 Å²	141.5	78%	0.784	82%	0.824	S	S	*	*			trans	157.3	74.5	166.6	0	0	0	0	0	116.4
29	K	26.2	Very low	24.9	Very low	204 Å²	204	139.9 Å²	139.9	89%	0.887	82%	0.817	S	S	*	*			trans	28.1	110	149.9	-70.4	179	176.9	177.8	0	119.7
30	D	26.8	Very low	25.5	Very low	158 Å²	158	139.2 Å²	139.2	85%	0.845	83%	0.825	S	S	*	*			trans	7.9	116.5	139.7	-80.7	-33.8	0	0	0	119
31	L	30.5	Very low	25.8	Very low	189 Å²	189	140.4 Å²	140.4	99%	0.99	82%	0.822	S	S	*	*			trans	-170	84.7	136.2	-100.7	140.2	0	0	0	108.4
32	G	23.4	Very low	26.3	Very low	68 Å²	68	145.8 Å²	145.8	70%	0.701	83%	0.827	S	S	*	*			trans	-140.6	101.8	180	0	0	0	0	0	111.4	K34	G32-K34 PolarHBondContact O-N 3.49Å
33	G	27.9	Very low	27.1	Very low	84 Å²	84	141.9 Å²	141.9	87%	0.866	82%	0.816	S	S	*	*			trans	-58.3	121.7	169.9	0	0	0	0	0	110.7
34	K	24.8	Very low	28	Very low	200 Å²	200	143.4 Å²	143.4	87%	0.87	82%	0.815	S	S	*	*			trans	-87.6	110.8	166.8	-80.8	-175.9	176.1	179.4	0	108.9	G32 Q36	G32-K34 PolarHBondContact O-N 3.49Å; K34-Q36 PolarHBondContact O-N 3.43Å; K34-Q36 VanDerWaalsContact O-N 3.1Å
35	L	27.1	Very low	29.1	Very low	174 Å²	174	138.6 Å²	138.6	91%	0.911	80%	0.798	S	S	*	*			trans	-47.1	109.1	155.4	-79	143.3	0	0	0	108.5	E37	L35-E37 PolarHBondContact O-N 3.44Å
36	Q	27.4	Very low	30.2	Very low	186 Å²	186	135.6 Å²	135.6	87%	0.869	78%	0.782	S	S	*	*			trans	-75.9	114.6	164.7	-84.9	-178.5	-11.1	0	0	107.7	K34 G38	K34-Q36 PolarHBondContact O-N 3.43Å; K34-Q36 VanDerWaalsContact O-N 3.1Å; Q36-G38 PolarHBondContact O-N 2.97Å; Q36-G38 VanDerWaalsContact O-N 3.15Å
37	E	26.8	Very low	31.7	Very low	194 Å²	194	134.3 Å²	134.3	91%	0.907	77%	0.774	S	S	*	*			trans	-54.1	115.6	159.8	-76.9	180	142.6	0	0	108.6	L35 G39	L35-E37 PolarHBondContact O-N 3.44Å; E37-G39 VanDerWaalsContact C-N 3.35Å; E37-G39 PolarHBondContact O-N 2.93Å
38	G	27.2	Very low	34	Very low	78 Å²	78	133.5 Å²	133.5	80%	0.804	76%	0.763	S	S	*	*			trans	-68.2	89.2	178	0	0	0	0	0	110.7	Q36 G40	Q36-G38 PolarHBondContact O-N 2.97Å; Q36-G38 VanDerWaalsContact O-N 3.15Å; G38-G40 PolarHBondContact O-N 3.15Å
39	G	27.2	Very low	36.6	Very low	64 Å²	64	130.4 Å²	130.4	66%	0.66	73%	0.729	S	S	*	*			trans	-59.3	116.4	159.1	0	0	0	0	0	108.3	E37 K41	E37-G39 VanDerWaalsContact C-N 3.35Å; E37-G39 PolarHBondContact O-N 2.93Å; G39-K41 VanDerWaalsContact C-N 3.27Å; G39-K41 PolarHBondContact O-N 3.44Å
40	G	32.2	Very low	39.6	Very low	80 Å²	80	123.9 Å²	123.9	83%	0.825	71%	0.706	S	S	*	*			trans	-56.2	88.4	175.8	0	0	0	0	0	110.9	G38 K42	G38-G40 PolarHBondContact O-N 3.15Å; G40-K42 PolarHBondContact O-N 2.84Å; G40-K42 VanDerWaalsContact O-N 3.13Å
41	K	31.5	Very low	42.5	Very low	190 Å²	190	118.9 Å²	118.9	83%	0.826	68%	0.679	S	S	*	*			trans	-67.2	107.8	167.1	-79.5	-178.4	177.3	175.5	0	106	G39 V43	G39-K41 VanDerWaalsContact C-N 3.27Å; G39-K41 PolarHBondContact O-N 3.44Å; K41-V43 PolarHBondContact O-N 3.01Å; K41-V43 VanDerWaalsContact O-N 3.07Å
42	K	32.4	Very low	45	Very low	179 Å²	179	116.3 Å²	116.3	78%	0.778	67%	0.666	S	S	*	*			trans	-47.5	118.2	163.7	-77.4	-178.4	174.1	-178.6	0	107.8	G40 E44	G40-K42 PolarHBondContact O-N 2.84Å; G40-K42 VanDerWaalsContact O-N 3.13Å; K42-E44 VanDerWaalsContact C-N 3.26Å; K42-E44 PolarHBondContact O-N 2.96Å
43	V	40.3	Very low	47.7	Very low	111 Å²	111	120.1 Å²	120.1	67%	0.673	66%	0.659	S	S	*	*			trans	-80.3	82.3	-179.9	-176.9	0	0	0	0	107.2	K41	K41-V43 PolarHBondContact O-N 3.01Å; K41-V43 VanDerWaalsContact O-N 3.07Å
44	E	40	Very low	50.3	Low	150 Å²	150	116.1 Å²	116.1	70%	0.701	62%	0.618	S	S	*	*			trans	-73.2	136.7	168	-66	-178.3	178.4	0	0	108.7	K42 G46	K42-E44 VanDerWaalsContact C-N 3.26Å; K42-E44 PolarHBondContact O-N 2.96Å; E44-G46 PolarHBondContact O-N 3.32Å
45	L	44.8	Very low	53.2	Low	95 Å²	95	107.7 Å²	107.7	50%	0.497	58%	0.582	S	S	.	*			trans	-51.9	109.8	166.6	-87.5	152.1	0	0	0	107.8	K47 E263	L45-K47 PolarHBondContact O-N 3.47Å; L45-E263 HydrophobicContact CB-CG 4.04Å
46	G	45.5	Very low	55.7	Low	38 Å²	38	102 Å²	102	39%	0.392	56%	0.557	S	S	.	*			trans	-56.9	131.6	-172.7	0	0	0	0	0	111.6	E44 K48	E44-G46 PolarHBondContact O-N 3.32Å; G46-K48 VanDerWaalsContact O-CG 3.29Å; G46-K48 WeakPolarHBondContact O-CG 3.37Å; G46-K48 PolarHBondContact O-N 3.15Å
47	K	56	Low	58.1	Low	140 Å²	140	96 Å²	96	61%	0.609	53%	0.53	S	S	*	.			trans	-58.5	104.6	176	-63.2	177.6	-175.7	173.6	0	109.7	L45 E263	L45-K47 PolarHBondContact O-N 3.47Å; K47-E263 CarbonylContact C-O 3.31Å; K47-E263 WeakPolarHBondContact CA-O 3.5Å
48	K	71.1	Confident	60.8	Low	145 Å²	145	86.8 Å²	86.8	63%	0.63	49%	0.487	S	S	*	.			trans	-127.7	-8.3	-170.4	-79.5	172.9	-177.7	179.2	0	113.4	G46 R53 E263	G46-K48 VanDerWaalsContact O-CG 3.29Å; G46-K48 WeakPolarHBondContact O-CG 3.37Å; G46-K48 PolarHBondContact O-N 3.15Å; K48-R53 WeakPolarHBondContact O-CD 3.26Å; K48-R53 PolarHBondContact O-NH1 3.17Å; K48-R53 VanDerWaalsContact O-NH1 3.14Å; K48-E263 PolarHBondContact N-O 3.32Å
49	V	80.4	Confident	63.4	Low	12 Å²	12	83.4 Å²	83.4	7%	0.073	45%	0.451	C	S	.	.	B	Isolated β-bridge	trans	-99.1	98.2	-177.3	-175.2	0	0	0	0	109.3	R53 I57 L257 E263 V264 D265	V49-R53 HydrophobicContact CG1-CB 4.2Å; V49-I57 HydrophobicContact CG1-CD1 3.99Å; V49-I57 HydrophobicContact CG2-CD1 4.5Å; V49-L257 HydrophobicContact CG1-CD1 4.1Å; V49-E263 HydrophobicContact CG2-CB 4.07Å; V49-E263 PolarHBondContact N-O 3.02Å; V49-V264 HydrophobicContact CB-CG2 4.14Å; V49-V264 HydrophobicContact CG1-CG2 4.19Å; V49-D265 PolarHBondContact O-N 3.1Å
50	T	88.4	Confident	65.6	Low	66 Å²	66	80.8 Å²	80.8	41%	0.405	42%	0.424	S	S	.	.			trans	-78.3	169.1	171.5	58.6	0	0	0	0	111.2	L52 R53 G54	T50-L52 PolarHBondContact O-N 3.27Å; T50-R53 WeakPolarHBondContact O-CB 3.48Å; T50-R53 PolarHBondContact O-N 2.65Å; T50-R53 VanDerWaalsContact O-N 3.1Å; T50-G54 PolarHBondContact O-N 3.48Å
51	L	87.3	Confident	67.7	Low	54 Å²	54	79.7 Å²	79.7	28%	0.283	40%	0.401	S	S	.	.	H	α-helix	trans	-51.4	-50.6	179.4	178.4	66.2	0	0	0	113.9	R53 G54 I55 T270 L273 A274	L51-R53 VanDerWaalsContact C-N 3.29Å; L51-R53 PolarHBondContact O-N 3.13Å; L51-G54 PolarHBondContact O-N 3.11Å; L51-G54 VanDerWaalsContact O-N 3.15Å; L51-I55 HydrophobicContact CD1-CD1 4.19Å; L51-I55 HydrophobicContact CD1-CG1 4.43Å; L51-I55 HydrophobicContact CG-CD1 4.03Å; L51-I55 WeakPolarHBondContact O-CG1 3.35Å; L51-I55 PolarHBondContact O-N 3.14Å; L51-T270 HydrophobicContact CB-CG2 4.14Å; L51-T270 HydrophobicContact CD1-CG2 4.19Å; L51-L273 HydrophobicContact CD1-CB 3.96Å; L51-L273 HydrophobicContact CD1-CD2 3.88Å; L51-L273 HydrophobicContact CD1-CG 3.93Å; L51-L273 HydrophobicContact CD2-CD2 3.5Å; L51-L273 VanDerWaalsContact CD2-CD2 3.5Å; L51-L273 HydrophobicContact CD2-CG 4.29Å; L51-L273 HydrophobicContact CG-CD2 4.35Å; L51-A274 HydrophobicContact CD1-CB 3.96Å
52	L	83.1	Confident	70	Confident	135 Å²	135	70.9 Å²	70.9	71%	0.707	36%	0.363	S	S	*	.	H	α-helix	trans	-63.1	-37.3	179.9	-68.7	175.6	0	0	0	112.1	T50 I55 S56	T50-L52 PolarHBondContact O-N 3.27Å; L52-I55 PolarHBondContact O-N 2.82Å; L52-S56 WeakPolarHBondContact O-CB 3.44Å; L52-S56 PolarHBondContact O-N 3.32Å
53	R	80.3	Confident	72.2	Confident	147 Å²	147	62.6 Å²	62.6	56%	0.555	33%	0.327	S	S	*	.	H	α-helix	trans	-66.8	-42	174.1	-71.3	-179	171.9	-160.9	-6.2	111.1	K48 V49 T50 L51 S56 I57	K48-R53 WeakPolarHBondContact O-CD 3.26Å; K48-R53 PolarHBondContact O-NH1 3.17Å; K48-R53 VanDerWaalsContact O-NH1 3.14Å; V49-R53 HydrophobicContact CG1-CB 4.2Å; T50-R53 WeakPolarHBondContact O-CB 3.48Å; T50-R53 PolarHBondContact O-N 2.65Å; T50-R53 VanDerWaalsContact O-N 3.1Å; L51-R53 VanDerWaalsContact C-N 3.29Å; L51-R53 PolarHBondContact O-N 3.13Å; R53-S56 PolarHBondContact O-N 3.35Å; R53-I57 WeakPolarHBondContact O-CB 3.28Å; R53-I57 WeakPolarHBondContact O-CD1 3.16Å; R53-I57 WeakPolarHBondContact O-CG1 3.39Å; R53-I57 PolarHBondContact O-N 2.82Å
54	G	82.1	Confident	73.7	Confident	0 Å²	0	57.6 Å²	57.6	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-59	-45.7	174.1	0	0	0	0	0	112.3	T50 L51 I57 I58	T50-G54 PolarHBondContact O-N 3.48Å; L51-G54 PolarHBondContact O-N 3.11Å; L51-G54 VanDerWaalsContact O-N 3.15Å; G54-I57 PolarHBondContact O-N 3.2Å; G54-I58 WeakPolarHBondContact O-CG1 3.19Å; G54-I58 PolarHBondContact O-N 3.34Å
55	I	85.4	Confident	74.9	Confident	23 Å²	23	50.9 Å²	50.9	12%	0.118	27%	0.268	C	S	.	.	H	α-helix	trans	-60.6	-48.1	175.6	-67.1	166.2	0	0	0	110.4	L51 L52 I57 I58 V59 A274 I277 S278 I281	L51-I55 HydrophobicContact CD1-CD1 4.19Å; L51-I55 HydrophobicContact CD1-CG1 4.43Å; L51-I55 HydrophobicContact CG-CD1 4.03Å; L51-I55 WeakPolarHBondContact O-CG1 3.35Å; L51-I55 PolarHBondContact O-N 3.14Å; L52-I55 PolarHBondContact O-N 2.82Å; I55-I57 VanDerWaalsContact C-N 3.35Å; I55-I57 PolarHBondContact O-N 3.4Å; I55-I58 PolarHBondContact O-N 2.64Å; I55-V59 HydrophobicContact CG2-CG2 4.07Å; I55-V59 WeakPolarHBondContact O-CB 3.2Å; I55-V59 VanDerWaalsContact O-CG2 3.29Å; I55-V59 WeakPolarHBondContact O-CG2 3.22Å; I55-V59 PolarHBondContact O-N 3.46Å; I55-A274 HydrophobicContact CG1-CB 4.12Å; I55-I277 HydrophobicContact CD1-CB 4.26Å; I55-I277 HydrophobicContact CD1-CD1 4.18Å; I55-I277 HydrophobicContact CD1-CG2 3.99Å; I55-I277 HydrophobicContact CG1-CG2 4.48Å; I55-S278 WeakPolarHBondContact CA-OG 3.04Å; I55-S278 PolarHBondContact O-OG 2.82Å; I55-I281 HydrophobicContact CG2-CD1 4.3Å
56	S	79.6	Confident	76.4	Confident	56 Å²	56	46.7 Å²	46.7	39%	0.392	25%	0.249	S	C	.	.	H	α-helix	trans	-61.1	-41.2	179.2	177.7	0	0	0	0	112.5	L52 R53 G60	L52-S56 WeakPolarHBondContact O-CB 3.44Å; L52-S56 PolarHBondContact O-N 3.32Å; R53-S56 PolarHBondContact O-N 3.35Å; S56-G60 PolarHBondContact O-N 3.07Å
57	I	78.4	Confident	78.1	Confident	59 Å²	59	45.1 Å²	45.1	30%	0.303	23%	0.231	S	C	.	.	H	α-helix	trans	-61.4	-49.1	175.3	-70.5	163.6	0	0	0	110.2	V49 R53 G54 I55 T61	V49-I57 HydrophobicContact CG1-CD1 3.99Å; V49-I57 HydrophobicContact CG2-CD1 4.5Å; R53-I57 WeakPolarHBondContact O-CB 3.28Å; R53-I57 WeakPolarHBondContact O-CD1 3.16Å; R53-I57 WeakPolarHBondContact O-CG1 3.39Å; R53-I57 PolarHBondContact O-N 2.82Å; G54-I57 PolarHBondContact O-N 3.2Å; I55-I57 VanDerWaalsContact C-N 3.35Å; I55-I57 PolarHBondContact O-N 3.4Å; I57-T61 WeakPolarHBondContact O-CB 3.22Å; I57-T61 VanDerWaalsContact O-CG2 3.26Å; I57-T61 WeakPolarHBondContact O-CG2 3.34Å; I57-T61 PolarHBondContact O-N 2.64Å; I57-T61 PolarHBondContact O-OG1 3.02Å
58	I	83	Confident	79.1	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-66.9	-48.9	-178	-64.8	170	0	0	0	110.8	G54 I55 G60 T61 I62 L257 A274 I275	G54-I58 WeakPolarHBondContact O-CG1 3.19Å; G54-I58 PolarHBondContact O-N 3.34Å; I55-I58 PolarHBondContact O-N 2.64Å; I58-G60 PolarHBondContact O-N 2.75Å; I58-T61 PolarHBondContact O-N 2.86Å; I58-T61 PolarHBondContact O-OG1 3Å; I58-I62 HydrophobicContact CG2-CD1 3.48Å; I58-I62 VanDerWaalsContact CG2-CD1 3.48Å; I58-I62 HydrophobicContact CG2-CG1 4.23Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.13Å; I58-I62 PolarHBondContact O-N 3.39Å; I58-L257 HydrophobicContact CD1-CB 3.91Å; I58-L257 HydrophobicContact CD1-CD2 3.8Å; I58-L257 HydrophobicContact CD1-CG 4.44Å; I58-L257 HydrophobicContact CG1-CB 3.98Å; I58-A274 HydrophobicContact CD1-CB 4.2Å; I58-I275 HydrophobicContact CD1-CB 4.39Å; I58-I275 HydrophobicContact CD1-CG1 3.64Å
59	V	82.4	Confident	79.4	Confident	7 Å²	7	34 Å²	34	4%	0.042	18%	0.184	C	C	.	.	H	α-helix	trans	-62.1	-46.9	-179.8	175.3	0	0	0	0	110.4	I55 T61 I62 I63 L204 I281 V282	I55-V59 HydrophobicContact CG2-CG2 4.07Å; I55-V59 WeakPolarHBondContact O-CB 3.2Å; I55-V59 VanDerWaalsContact O-CG2 3.29Å; I55-V59 WeakPolarHBondContact O-CG2 3.22Å; I55-V59 PolarHBondContact O-N 3.46Å; V59-T61 VanDerWaalsContact C-N 3.29Å; V59-T61 PolarHBondContact O-N 2.67Å; V59-I62 PolarHBondContact O-N 2.99Å; V59-I63 HydrophobicContact CG1-CD1 3.5Å; V59-I63 VanDerWaalsContact CG1-CD1 3.5Å; V59-I63 HydrophobicContact CG1-CG1 4.1Å; V59-I63 WeakPolarHBondContact O-CB 3.36Å; V59-I63 VanDerWaalsContact O-CG1 3.28Å; V59-I63 WeakPolarHBondContact O-CG1 3.36Å; V59-I63 PolarHBondContact O-N 3Å; V59-L204 HydrophobicContact CG1-CD2 3.82Å; V59-I281 HydrophobicContact CG2-CG2 4.33Å; V59-V282 HydrophobicContact CG2-CG2 4.37Å
60	G	73.8	Confident	79.8	Confident	9 Å²	9	33.5 Å²	33.5	9%	0.093	18%	0.181	C	C	.	.	H	α-helix	trans	-68.2	-24.4	-180	0	0	0	0	0	114.3	S56 I58	S56-G60 PolarHBondContact O-N 3.07Å; I58-G60 PolarHBondContact O-N 2.75Å
61	T	74.8	Confident	79.8	Confident	57 Å²	57	30.4 Å²	30.4	35%	0.35	16%	0.162	S	C	.	.	H	α-helix	trans	-85.1	-36.3	175.2	49.6	0	0	0	0	113.5	I57 I58 V59 Y256	I57-T61 WeakPolarHBondContact O-CB 3.22Å; I57-T61 VanDerWaalsContact O-CG2 3.26Å; I57-T61 WeakPolarHBondContact O-CG2 3.34Å; I57-T61 PolarHBondContact O-N 2.64Å; I57-T61 PolarHBondContact O-OG1 3.02Å; I58-T61 PolarHBondContact O-N 2.86Å; I58-T61 PolarHBondContact O-OG1 3Å; V59-T61 VanDerWaalsContact C-N 3.29Å; V59-T61 PolarHBondContact O-N 2.67Å; T61-Y256 HydrophobicContact CG2-CD2 4.07Å; T61-Y256 HydrophobicContact CG2-CG 4.33Å
62	I	81.4	Confident	79.9	Confident	5 Å²	5	30.1 Å²	30.1	3%	0.026	16%	0.159	C	C	.	.	H	α-helix	trans	-74.9	-46.3	176.7	-60.5	168	0	0	0	110.1	I58 V59 G64 W254 M279 V282 Y286	I58-I62 HydrophobicContact CG2-CD1 3.48Å; I58-I62 VanDerWaalsContact CG2-CD1 3.48Å; I58-I62 HydrophobicContact CG2-CG1 4.23Å; I58-I62 VanDerWaalsContact O-CG1 3.31Å; I58-I62 WeakPolarHBondContact O-CG1 3.13Å; I58-I62 PolarHBondContact O-N 3.39Å; V59-I62 PolarHBondContact O-N 2.99Å; I62-G64 VanDerWaalsContact C-N 3.28Å; I62-G64 PolarHBondContact O-N 3.31Å; I62-W254 HydrophobicContact CD1-CB 3.87Å; I62-M279 HydrophobicContact CD1-SD 3.83Å; I62-V282 HydrophobicContact CB-CG1 4.45Å; I62-V282 HydrophobicContact CB-CG2 4.23Å; I62-V282 HydrophobicContact CD1-CG2 4.22Å; I62-V282 HydrophobicContact CG2-CG1 3.64Å; I62-V282 HydrophobicContact CG2-CG2 4.29Å; I62-Y286 HydrophobicContact CG2-CE2 4.5Å; I62-Y286 PolarHBondContact O-OH 2.86Å
63	I	78.6	Confident	80	Confident	5 Å²	5	24.5 Å²	24.5	3%	0.026	13%	0.133	C	C	.	.	S	Bend	trans	-74.4	85.6	177.5	-58.3	-172.6	0	0	0	109.3	V59 I207 V282 Y286	V59-I63 HydrophobicContact CG1-CD1 3.5Å; V59-I63 VanDerWaalsContact CG1-CD1 3.5Å; V59-I63 HydrophobicContact CG1-CG1 4.1Å; V59-I63 WeakPolarHBondContact O-CB 3.36Å; V59-I63 VanDerWaalsContact O-CG1 3.28Å; V59-I63 WeakPolarHBondContact O-CG1 3.36Å; V59-I63 PolarHBondContact O-N 3Å; I63-I207 HydrophobicContact CB-CD1 4.39Å; I63-I207 HydrophobicContact CD1-CD1 3.9Å; I63-I207 HydrophobicContact CG2-CD1 3.1Å; I63-V282 HydrophobicContact CD1-CG2 4.25Å; I63-V282 HydrophobicContact CG1-CG1 4.5Å; I63-V282 HydrophobicContact CG1-CG2 3.98Å; I63-Y286 HydrophobicContact CG1-CE1 4.15Å
64	G	71.1	Confident	80.6	Confident	7 Å²	7	17.5 Å²	17.5	7%	0.072	11%	0.107	C	C	.	.	S	Bend	trans	-134.2	-146.3	174.2	0	0	0	0	0	112	I62 G66	I62-G64 VanDerWaalsContact C-N 3.28Å; I62-G64 PolarHBondContact O-N 3.31Å; G64-G66 PolarHBondContact O-N 2.9Å
65	A	65.3	Low	81	Confident	8 Å²	8	17.7 Å²	17.7	7%	0.066	11%	0.108	C	C	.	.	T	Hydrogen-bonded Turn	trans	-60.7	-19	-176.7	0	0	0	0	0	114.6	I67 F68 I69	A65-I67 VanDerWaalsContact C-N 3.33Å; A65-I67 PolarHBondContact O-N 3.19Å; A65-F68 PolarHBondContact O-N 3.33Å; A65-F68 VanDerWaalsContact O-N 3.14Å; A65-I69 HydrophobicContact CB-CD1 4.49Å; A65-I69 PolarHBondContact O-N 3.09Å
66	G	76.2	Confident	81.2	Confident	8 Å²	8	22.8 Å²	22.8	8%	0.082	13%	0.129	C	C	.	.	H	α-helix	trans	-59.7	-36.4	-175.6	0	0	0	0	0	114.5	G64 F68 I69 S70	G64-G66 PolarHBondContact O-N 2.9Å; G66-F68 PolarHBondContact O-N 3Å; G66-I69 PolarHBondContact O-N 2.95Å; G66-S70 VanDerWaalsContact O-CB 3.26Å; G66-S70 WeakPolarHBondContact O-CB 3.42Å; G66-S70 PolarHBondContact O-N 3.35Å; G66-S70 PolarHBondContact O-OG 3.06Å
67	I	81.6	Confident	81.6	Confident	4 Å²	4	22.1 Å²	22.1	2%	0.021	12%	0.12	C	C	.	.	H	α-helix	trans	-70.4	-21.2	179.8	-168.4	53.6	0	0	0	112.9	A65 P71 W88 Y286 T289	A65-I67 VanDerWaalsContact C-N 3.33Å; A65-I67 PolarHBondContact O-N 3.19Å; I67-P71 WeakPolarHBondContact O-CD 3.45Å; I67-P71 WeakPolarHBondContact O-CG 3.48Å; I67-W88 HydrophobicContact CD1-CH2 3.6Å; I67-W88 HydrophobicContact CD1-CZ2 3.97Å; I67-W88 HydrophobicContact CD1-CZ3 4.14Å; I67-Y286 HydrophobicContact CB-CD1 4.22Å; I67-Y286 HydrophobicContact CB-CE1 3.82Å; I67-Y286 HydrophobicContact CD1-CD1 3.61Å; I67-Y286 HydrophobicContact CD1-CD2 4.39Å; I67-Y286 HydrophobicContact CD1-CE1 4.08Å; I67-Y286 HydrophobicContact CD1-CG 3.77Å; I67-Y286 HydrophobicContact CG1-CD1 3.86Å; I67-Y286 HydrophobicContact CG1-CE1 3.99Å; I67-T289 HydrophobicContact CD1-CG2 4.39Å; I67-T289 HydrophobicContact CG1-CG2 3.99Å
68	F	77.1	Confident	82.1	Confident	16 Å²	16	19.3 Å²	19.3	7%	0.07	11%	0.106	C	C	.	.	H	α-helix	trans	-90.3	-17.2	179.2	-53.2	-58.2	0	0	0	113.1	A65 G66 L206 A309 V328	A65-F68 PolarHBondContact O-N 3.33Å; A65-F68 VanDerWaalsContact O-N 3.14Å; G66-F68 PolarHBondContact O-N 3Å; F68-L206 HydrophobicContact CZ-CD2 4.16Å; F68-A309 HydrophobicContact CD1-CB 3.67Å; F68-A309 HydrophobicContact CE1-CB 4.14Å; F68-A309 HydrophobicContact CG-CB 4.33Å; F68-V328 HydrophobicContact CD2-CG1 3.91Å; F68-V328 HydrophobicContact CD2-CG2 4.31Å; F68-V328 HydrophobicContact CE1-CG2 4.42Å; F68-V328 HydrophobicContact CE2-CG1 4.16Å; F68-V328 HydrophobicContact CE2-CG2 4.06Å; F68-V328 HydrophobicContact CZ-CG2 4.1Å
69	I	77.6	Confident	82.2	Confident	35 Å²	35	20.5 Å²	20.5	18%	0.179	12%	0.118	C	C	.	.	H	α-helix	trans	-100.9	-44	-178.3	-60.8	170.2	0	0	0	111	A65 G66 P71	A65-I69 HydrophobicContact CB-CD1 4.49Å; A65-I69 PolarHBondContact O-N 3.09Å; G66-I69 PolarHBondContact O-N 2.95Å; I69-P71 VanDerWaalsContact C-CD 3.44Å
70	S	87.4	Confident	82.5	Confident	3 Å²	3	20.5 Å²	20.5	2%	0.021	12%	0.118	C	C	.	.	H	α-helix	trans	-70.6	-29.8	-168.1	-48.6	0	0	0	0	116.2	G66 K72 G73 I74 S246	G66-S70 VanDerWaalsContact O-CB 3.26Å; G66-S70 WeakPolarHBondContact O-CB 3.42Å; G66-S70 PolarHBondContact O-N 3.35Å; G66-S70 PolarHBondContact O-OG 3.06Å; S70-K72 VanDerWaalsContact C-N 3.3Å; S70-K72 PolarHBondContact O-N 3.1Å; S70-G73 PolarHBondContact O-N 2.97Å; S70-G73 VanDerWaalsContact O-N 3.15Å; S70-I74 WeakPolarHBondContact O-CG1 3.4Å; S70-I74 PolarHBondContact O-N 2.73Å; S70-S246 WeakPolarHBondContact CB-O 3.23Å; S70-S246 PolarHBondContact OG-O 3.05Å
71	P	89.9	Confident	83.3	Confident	0 Å²	0	20.8 Å²	20.8	0%	0	12%	0.118	C	C	.	.	H	α-helix	trans	-53.6	-45.1	179.2	-28.9	35.3	0	0	0	113.2	I67 I69 G73 I74 L75 W88 N290 Y293 L302	I67-P71 WeakPolarHBondContact O-CD 3.45Å; I67-P71 WeakPolarHBondContact O-CG 3.48Å; I69-P71 VanDerWaalsContact C-CD 3.44Å; P71-G73 PolarHBondContact O-N 3.13Å; P71-I74 PolarHBondContact O-N 3.18Å; P71-L75 WeakPolarHBondContact O-CB 3.44Å; P71-L75 PolarHBondContact O-N 3.15Å; P71-W88 HydrophobicContact CG-CZ2 4.07Å; P71-N290 WeakPolarHBondContact CB-OD1 3.29Å; P71-Y293 HydrophobicContact CB-CD2 4.34Å; P71-Y293 HydrophobicContact CG-CD2 4.16Å; P71-Y293 HydrophobicContact CG-CE2 3.93Å; P71-L302 HydrophobicContact CB-CD2 4.33Å
72	K	88.1	Confident	84	Confident	48 Å²	48	18 Å²	18	21%	0.209	10%	0.101	C	C	.	.	H	α-helix	trans	-61.4	-45.8	178.4	179.5	172.2	-177.1	157.8	0	111.9	S70 K76 L302 L303 S305 V308	S70-K72 VanDerWaalsContact C-N 3.3Å; S70-K72 PolarHBondContact O-N 3.1Å; K72-K76 WeakPolarHBondContact O-CB 3.25Å; K72-K76 PolarHBondContact O-N 3.1Å; K72-L302 HydrophobicContact CB-CD2 4.18Å; K72-L303 WeakPolarHBondContact CE-O 3.46Å; K72-L303 HydrophobicContact CG-CD2 4.42Å; K72-L303 PolarHBondContact NZ-O 3.02Å; K72-S305 WeakPolarHBondContact CD-O 3.25Å; K72-S305 PolarHBondContact NZ-O 3.48Å; K72-V308 HydrophobicContact CB-CG2 4.4Å
73	G	86	Confident	84.5	Confident	17 Å²	17	20 Å²	20	18%	0.175	11%	0.11	C	C	.	.	H	α-helix	trans	-62.9	-46	178.2	0	0	0	0	0	112.4	S70 P71 H77	S70-G73 PolarHBondContact O-N 2.97Å; S70-G73 VanDerWaalsContact O-N 3.15Å; P71-G73 PolarHBondContact O-N 3.13Å; G73-H77 WeakPolarHBondContact O-CB 3.38Å; G73-H77 PolarHBondContact O-CD2 2.98Å; G73-H77 PolarHBondContact O-N 3.3Å
74	I	91.6	Very high	85.2	Confident	0 Å²	0	19.7 Å²	19.7	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-65.2	-46.4	179.6	-62.9	163.4	0	0	0	110.6	S70 P71 H77 S78 V87 W88 A243	S70-I74 WeakPolarHBondContact O-CG1 3.4Å; S70-I74 PolarHBondContact O-N 2.73Å; P71-I74 PolarHBondContact O-N 3.18Å; I74-H77 PolarHBondContact O-N 2.91Å; I74-S78 VanDerWaalsContact O-CB 3.23Å; I74-S78 WeakPolarHBondContact O-CB 3.26Å; I74-S78 PolarHBondContact O-N 3.31Å; I74-S78 PolarHBondContact O-OG 3.12Å; I74-V87 HydrophobicContact CG2-CB 4.01Å; I74-V87 HydrophobicContact CG2-CG1 3.9Å; I74-W88 HydrophobicContact CD1-CD2 3.76Å; I74-W88 HydrophobicContact CD1-CE3 4.37Å; I74-W88 HydrophobicContact CD1-CG 4.27Å; I74-W88 HydrophobicContact CD1-CH2 3.99Å; I74-W88 HydrophobicContact CD1-CZ2 3.35Å; I74-W88 HydrophobicContact CD1-CZ3 4.44Å; I74-A243 HydrophobicContact CG2-CB 4.49Å
75	L	91.4	Very high	86.2	Confident	4 Å²	4	20.6 Å²	20.6	2%	0.021	11%	0.112	C	C	.	.	H	α-helix	trans	-64.2	-44.6	179.9	-177.4	61.8	0	0	0	111.7	P71 H77 S78 G79 V81 Y294 A299 L302 L303	P71-L75 WeakPolarHBondContact O-CB 3.44Å; P71-L75 PolarHBondContact O-N 3.15Å; L75-H77 PolarHBondContact O-N 3.44Å; L75-S78 PolarHBondContact O-N 3.44Å; L75-S78 PolarHBondContact O-OG 3.39Å; L75-G79 PolarHBondContact O-N 3.41Å; L75-V81 HydrophobicContact CD1-CG2 4.39Å; L75-Y294 HydrophobicContact CD1-CE1 4.31Å; L75-Y294 HydrophobicContact CD2-CE1 3.91Å; L75-A299 HydrophobicContact CD1-CB 4.5Å; L75-A299 HydrophobicContact CD2-CB 4.03Å; L75-L302 HydrophobicContact CB-CD2 4.45Å; L75-L302 HydrophobicContact CD2-CB 4.13Å; L75-L302 HydrophobicContact CD2-CD2 3.82Å; L75-L302 HydrophobicContact CD2-CG 4.37Å; L75-L303 HydrophobicContact CB-CD2 4.17Å; L75-L303 HydrophobicContact CD2-CD2 4.11Å; L75-L303 HydrophobicContact CD2-CG 3.96Å; L75-L303 HydrophobicContact CG-CD2 4.09Å; L75-L303 HydrophobicContact CG-CG 4.28Å
76	K	89.5	Confident	87.6	Confident	131 Å²	131	23.2 Å²	23.2	57%	0.57	13%	0.128	S	C	*	.	H	α-helix	trans	-56.1	-38.8	179.2	-175.7	179.2	179.7	-177.6	0	112.1	K72 L303	K72-K76 WeakPolarHBondContact O-CB 3.25Å; K72-K76 PolarHBondContact O-N 3.1Å; K76-L303 HydrophobicContact CB-CD2 3.74Å
77	H	87.9	Confident	88.5	Confident	42 Å²	42	23 Å²	23	19%	0.194	12%	0.124	C	C	.	.	H	α-helix	trans	-96.6	-22.4	-173.7	-71.6	-55.4	0	0	0	114.5	G73 I74 L75 G239 L242 A243	G73-H77 WeakPolarHBondContact O-CB 3.38Å; G73-H77 PolarHBondContact O-CD2 2.98Å; G73-H77 PolarHBondContact O-N 3.3Å; I74-H77 PolarHBondContact O-N 2.91Å; L75-H77 PolarHBondContact O-N 3.44Å; H77-G239 WeakPolarHBondContact CB-O 3.49Å; H77-G239 CarbonylContact O-C 3.57Å; H77-G239 WeakPolarHBondContact O-CA 3.42Å; H77-L242 HydrophobicContact CB-CB 4.28Å; H77-L242 VanDerWaalsContact CE1-CD1 3.5Å; H77-L242 WeakPolarHBondContact CE1-CD1 3.48Å; H77-A243 HydrophobicContact CB-CB 3.8Å
78	S	88.3	Confident	89.1	Confident	0 Å²	0	22.8 Å²	22.8	0%	0	12%	0.124	C	C	.	.	H	α-helix	trans	-85.1	-26.9	173.1	58.5	0	0	0	0	112.4	I74 L75 S80 S84 Q236	I74-S78 VanDerWaalsContact O-CB 3.23Å; I74-S78 WeakPolarHBondContact O-CB 3.26Å; I74-S78 PolarHBondContact O-N 3.31Å; I74-S78 PolarHBondContact O-OG 3.12Å; L75-S78 PolarHBondContact O-N 3.44Å; L75-S78 PolarHBondContact O-OG 3.39Å; S78-S80 PolarHBondContact O-N 2.86Å; S78-S80 VanDerWaalsContact O-N 3.15Å; S78-S84 WeakPolarHBondContact OG-CB 3.32Å; S78-Q236 PolarHBondContact O-N 3.38Å
79	G	85.3	Confident	90.1	Very high	25 Å²	25	26 Å²	26	26%	0.258	14%	0.141	S	C	.	.			trans	75.7	-11	175.4	0	0	0	0	0	115.3	L75 K234	L75-G79 PolarHBondContact O-N 3.41Å; G79-K234 CarbonylContact C-O 3.59Å; G79-K234 WeakPolarHBondContact CA-O 3.44Å; G79-K234 WeakPolarHBondContact O-CB 3.3Å
80	S	89.5	Confident	90.9	Very high	7 Å²	7	25.8 Å²	25.8	5%	0.049	14%	0.144	C	C	.	.	S	Bend	trans	-143.4	144.4	-176.3	-174.9	0	0	0	0	111.7	S78 M83 S84 A229	S78-S80 PolarHBondContact O-N 2.86Å; S78-S80 VanDerWaalsContact O-N 3.15Å; S80-M83 PolarHBondContact O-N 2.81Å; S80-S84 WeakPolarHBondContact O-CB 3.22Å; S80-S84 PolarHBondContact O-N 2.85Å; S80-A229 PolarHBondContact OG-O 3.05Å
81	V	90.3	Very high	91.3	Very high	14 Å²	14	25.7 Å²	25.7	9%	0.085	14%	0.143	C	C	.	.	H	α-helix	trans	-61.7	-48.4	-173.8	173.1	0	0	0	0	111.5	L75 S84 L85 F226 A229 Y294 A299	L75-V81 HydrophobicContact CD1-CG2 4.39Å; V81-S84 WeakPolarHBondContact O-CB 3.35Å; V81-S84 PolarHBondContact O-N 3Å; V81-S84 PolarHBondContact O-OG 2.83Å; V81-L85 PolarHBondContact O-N 3.37Å; V81-L85 VanDerWaalsContact O-N 3.11Å; V81-F226 HydrophobicContact CG1-CD1 4.34Å; V81-F226 HydrophobicContact CG1-CE1 4.25Å; V81-A229 HydrophobicContact CB-CB 4.48Å; V81-Y294 HydrophobicContact CG1-CD1 4Å; V81-Y294 HydrophobicContact CG1-CD2 3.47Å; V81-Y294 VanDerWaalsContact CG1-CD2 3.47Å; V81-Y294 HydrophobicContact CG1-CE1 4.27Å; V81-Y294 HydrophobicContact CG1-CE2 3.77Å; V81-Y294 HydrophobicContact CG1-CG 3.59Å; V81-Y294 HydrophobicContact CG2-CD1 4.08Å; V81-Y294 HydrophobicContact CG2-CE1 4.12Å; V81-Y294 HydrophobicContact CG2-CG 4.5Å; V81-A299 HydrophobicContact CG2-CB 4.08Å
82	G	90.4	Very high	91.5	Very high	0 Å²	0	25.7 Å²	25.7	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-66.4	-37.7	-179.9	0	0	0	0	0	112.8	L85 T86 A229 F230	G82-L85 PolarHBondContact O-N 3.14Å; G82-T86 PolarHBondContact O-N 3.45Å; G82-T86 PolarHBondContact O-OG1 3.47Å; G82-A229 VanDerWaalsContact CA-O 3.24Å; G82-A229 WeakPolarHBondContact CA-O 3.34Å; G82-A229 PolarHBondContact N-O 3.31Å; G82-F230 VanDerWaalsContact C-CE1 3.47Å
83	M	91.1	Very high	91.9	Very high	45 Å²	45	26.6 Å²	26.6	22%	0.222	15%	0.153	C	C	.	.	H	α-helix	trans	-67.3	-37.6	171.9	-70	-48.9	-67.5	0	0	111.8	S80 L85 T86 V87 F230 V235 M240	S80-M83 PolarHBondContact O-N 2.81Å; M83-L85 VanDerWaalsContact C-N 3.33Å; M83-L85 PolarHBondContact O-N 3.11Å; M83-T86 WeakPolarHBondContact O-CB 3.24Å; M83-T86 PolarHBondContact O-N 3.46Å; M83-V87 WeakPolarHBondContact O-CG2 3.44Å; M83-V87 PolarHBondContact O-N 2.81Å; M83-F230 HydrophobicContact SD-CD1 4.46Å; M83-V235 HydrophobicContact CB-CG2 4.46Å; M83-V235 HydrophobicContact CG-CB 4.44Å; M83-V235 HydrophobicContact CG-CG1 4.06Å; M83-V235 HydrophobicContact CG-CG2 3.47Å; M83-V235 VanDerWaalsContact CG-CG2 3.47Å; M83-M240 HydrophobicContact CB-CE 4.32Å; M83-M240 HydrophobicContact CE-CE 3.3Å
84	S	92.9	Very high	92.3	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	15%	0.152	C	C	.	.	H	α-helix	trans	-59.4	-42.9	175.2	85.4	0	0	0	0	112	S78 S80 V81 V87 W88 Y294	S78-S84 WeakPolarHBondContact OG-CB 3.32Å; S80-S84 WeakPolarHBondContact O-CB 3.22Å; S80-S84 PolarHBondContact O-N 2.85Å; V81-S84 WeakPolarHBondContact O-CB 3.35Å; V81-S84 PolarHBondContact O-N 3Å; V81-S84 PolarHBondContact O-OG 2.83Å; S84-V87 PolarHBondContact O-N 3.1Å; S84-W88 PolarHBondContact O-N 2.96Å; S84-Y294 WeakPolarHBondContact OG-CE2 3.36Å; S84-Y294 PolarHBondContact OG-OH 3.06Å
85	L	93.7	Very high	92.4	Very high	26 Å²	26	27.2 Å²	27.2	14%	0.136	15%	0.152	C	C	.	.	H	α-helix	trans	-66.6	-38.1	176.8	-66.8	174.8	0	0	0	111.8	V81 G82 M83 V87 W88 I89 F226 N290 V291 Y294	V81-L85 PolarHBondContact O-N 3.37Å; V81-L85 VanDerWaalsContact O-N 3.11Å; G82-L85 PolarHBondContact O-N 3.14Å; M83-L85 VanDerWaalsContact C-N 3.33Å; M83-L85 PolarHBondContact O-N 3.11Å; L85-V87 VanDerWaalsContact C-N 3.33Å; L85-V87 PolarHBondContact O-N 3.43Å; L85-W88 WeakPolarHBondContact O-CB 3.02Å; L85-W88 PolarHBondContact O-N 3.32Å; L85-I89 WeakPolarHBondContact O-CG1 3.37Å; L85-I89 PolarHBondContact O-N 3.38Å; L85-I89 VanDerWaalsContact O-N 3.11Å; L85-F226 HydrophobicContact CD1-CE1 4.39Å; L85-N290 HydrophobicContact CD2-CB 3.68Å; L85-V291 HydrophobicContact CD1-CG2 4.16Å; L85-V291 HydrophobicContact CD2-CG2 4.13Å; L85-Y294 HydrophobicContact CD2-CD2 4.31Å; L85-Y294 HydrophobicContact CD2-CE2 4.1Å; L85-Y294 HydrophobicContact CG-CE2 4.29Å
86	T	94.1	Very high	92.6	Very high	63 Å²	63	29.5 Å²	29.5	39%	0.387	16%	0.164	S	C	.	.	H	α-helix	trans	-63.1	-40.9	174.8	-54.6	0	0	0	0	111.2	G82 M83 W88 I89 A90	G82-T86 PolarHBondContact O-N 3.45Å; G82-T86 PolarHBondContact O-OG1 3.47Å; M83-T86 WeakPolarHBondContact O-CB 3.24Å; M83-T86 PolarHBondContact O-N 3.46Å; T86-W88 VanDerWaalsContact C-N 3.35Å; T86-W88 PolarHBondContact O-N 3.13Å; T86-I89 PolarHBondContact O-N 3.09Å; T86-A90 WeakPolarHBondContact O-CB 3.34Å; T86-A90 PolarHBondContact O-N 3.04Å
87	V	94.5	Very high	92.9	Very high	3 Å²	3	25.1 Å²	25.1	2%	0.018	15%	0.145	C	C	.	.	H	α-helix	trans	-63.7	-38.8	175	172.1	0	0	0	0	111.4	I74 M83 S84 L85 A90 C91 M240 A243 F244	I74-V87 HydrophobicContact CG2-CB 4.01Å; I74-V87 HydrophobicContact CG2-CG1 3.9Å; M83-V87 WeakPolarHBondContact O-CG2 3.44Å; M83-V87 PolarHBondContact O-N 2.81Å; S84-V87 PolarHBondContact O-N 3.1Å; L85-V87 VanDerWaalsContact C-N 3.33Å; L85-V87 PolarHBondContact O-N 3.43Å; V87-A90 PolarHBondContact O-N 2.89Å; V87-C91 WeakPolarHBondContact O-CB 3.32Å; V87-C91 PolarHBondContact O-N 3.25Å; V87-C91 PolarHBondContact O-SG 2.85Å; V87-M240 HydrophobicContact CG2-CE 4.44Å; V87-M240 HydrophobicContact CG2-SD 3.82Å; V87-A243 HydrophobicContact CG1-CB 4.22Å; V87-F244 HydrophobicContact CG1-CD1 4.42Å; V87-F244 HydrophobicContact CG1-CG 4.42Å; V87-F244 HydrophobicContact CG2-CE2 4.38Å
88	W	95.5	Very high	93.2	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-59	-48.7	173.3	-83.1	107.8	0	0	0	112.1	I67 P71 I74 S84 L85 T86 A90 C91 G92 A250 Y251 Y286 V287 N290	I67-W88 HydrophobicContact CD1-CH2 3.6Å; I67-W88 HydrophobicContact CD1-CZ2 3.97Å; I67-W88 HydrophobicContact CD1-CZ3 4.14Å; P71-W88 HydrophobicContact CG-CZ2 4.07Å; I74-W88 HydrophobicContact CD1-CD2 3.76Å; I74-W88 HydrophobicContact CD1-CE3 4.37Å; I74-W88 HydrophobicContact CD1-CG 4.27Å; I74-W88 HydrophobicContact CD1-CH2 3.99Å; I74-W88 HydrophobicContact CD1-CZ2 3.35Å; I74-W88 HydrophobicContact CD1-CZ3 4.44Å; S84-W88 PolarHBondContact O-N 2.96Å; L85-W88 WeakPolarHBondContact O-CB 3.02Å; L85-W88 PolarHBondContact O-N 3.32Å; T86-W88 VanDerWaalsContact C-N 3.35Å; T86-W88 PolarHBondContact O-N 3.13Å; W88-A90 PolarHBondContact O-N 3.42Å; W88-C91 PolarHBondContact O-N 3.46Å; W88-G92 PolarHBondContact O-N 3.24Å; W88-A250 HydrophobicContact CH2-CB 3.64Å; W88-A250 HydrophobicContact CZ3-CB 3.61Å; W88-Y251 HydrophobicContact CE3-CD2 4.46Å; W88-Y251 AromaticContact CE3-CE2 3.55Å; W88-Y251 HydrophobicContact CE3-CE2 3.55Å; W88-Y251 HydrophobicContact CZ3-CD2 4.42Å; W88-Y251 AromaticContact CZ3-CE2 3.88Å; W88-Y251 HydrophobicContact CZ3-CE2 3.88Å; W88-Y251 WeakPolarHBondContact O-CE2 3.33Å; W88-Y251 PolarHBondContact O-OH 2.85Å; W88-Y286 AromaticContact CE3-CD2 3.84Å; W88-Y286 HydrophobicContact CE3-CD2 3.84Å; W88-Y286 HydrophobicContact CE3-CG 4.27Å; W88-Y286 HydrophobicContact CH2-CD2 4.28Å; W88-Y286 AromaticContact CZ3-CD2 3.33Å; W88-Y286 HydrophobicContact CZ3-CD2 3.33Å; W88-Y286 AromaticContact CZ3-CE2 3.96Å; W88-Y286 HydrophobicContact CZ3-CE2 3.96Å; W88-Y286 AromaticContact CZ3-CG 3.92Å; W88-Y286 HydrophobicContact CZ3-CG 3.92Å; W88-V287 HydrophobicContact CB-CG2 4.17Å; W88-N290 WeakPolarHBondContact CZ2-ND2 3.48Å; W88-N290 PolarHBondContact NE1-ND2 2.93Å; W88-N290 VanDerWaalsContact NE1-ND2 3.16Å; W88-N290 PolarHBondContact NE1-OD1 3.38Å
89	I	96.2	Very high	93.5	Very high	84 Å²	84	23.1 Å²	23.1	43%	0.431	14%	0.136	S	C	.	.	H	α-helix	trans	-61.1	-47.3	177.7	-64.9	167.8	0	0	0	110.5	L85 T86 C91 G92 V93 V287	L85-I89 WeakPolarHBondContact O-CG1 3.37Å; L85-I89 PolarHBondContact O-N 3.38Å; L85-I89 VanDerWaalsContact O-N 3.11Å; T86-I89 PolarHBondContact O-N 3.09Å; I89-C91 PolarHBondContact O-N 3.46Å; I89-G92 WeakPolarHBondContact O-CA 3.36Å; I89-G92 PolarHBondContact O-N 3.46Å; I89-G92 VanDerWaalsContact O-N 3.11Å; I89-V93 WeakPolarHBondContact O-CG2 3.37Å; I89-V93 PolarHBondContact O-N 3.47Å; I89-V287 HydrophobicContact CG1-CG2 3.64Å
90	A	95.4	Very high	94	Very high	30 Å²	30	23 Å²	23	25%	0.248	13%	0.129	C	C	.	.	H	α-helix	trans	-62.5	-41.6	-179.8	0	0	0	0	0	112	T86 V87 W88 G92 V93 L94 F244	T86-A90 WeakPolarHBondContact O-CB 3.34Å; T86-A90 PolarHBondContact O-N 3.04Å; V87-A90 PolarHBondContact O-N 2.89Å; W88-A90 PolarHBondContact O-N 3.42Å; A90-G92 VanDerWaalsContact C-N 3.32Å; A90-G92 PolarHBondContact O-N 3.19Å; A90-V93 PolarHBondContact O-N 3.06Å; A90-L94 WeakPolarHBondContact O-CB 3.35Å; A90-L94 WeakPolarHBondContact O-CG 3.45Å; A90-L94 PolarHBondContact O-N 3.39Å; A90-F244 HydrophobicContact CB-CE1 3.58Å; A90-F244 HydrophobicContact CB-CZ 3.86Å
91	C	94.9	Very high	94.3	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-61.2	-39	172.5	-70.4	0	0	0	0	112.2	V87 W88 I89 S95 M248 Y251	V87-C91 WeakPolarHBondContact O-CB 3.32Å; V87-C91 PolarHBondContact O-N 3.25Å; V87-C91 PolarHBondContact O-SG 2.85Å; W88-C91 PolarHBondContact O-N 3.46Å; I89-C91 PolarHBondContact O-N 3.46Å; C91-S95 VanDerWaalsContact O-CB 3.23Å; C91-S95 WeakPolarHBondContact O-CB 3.4Å; C91-S95 PolarHBondContact O-N 2.8Å; C91-S95 PolarHBondContact O-OG 2.85Å; C91-M248 HydrophobicContact CB-CG 4.48Å; C91-M248 HydrophobicContact CB-SD 3.98Å; C91-Y251 HydrophobicContact CB-CD2 3.68Å; C91-Y251 HydrophobicContact CB-CE2 3.67Å
92	G	95.3	Very high	94.4	Very high	1 Å²	1	22 Å²	22	1%	0.01	12%	0.123	C	C	.	.	H	α-helix	trans	-62	-45.1	174.7	0	0	0	0	0	112.6	W88 I89 A90 S95 L96	W88-G92 PolarHBondContact O-N 3.24Å; I89-G92 WeakPolarHBondContact O-CA 3.36Å; I89-G92 PolarHBondContact O-N 3.46Å; I89-G92 VanDerWaalsContact O-N 3.11Å; A90-G92 VanDerWaalsContact C-N 3.32Å; A90-G92 PolarHBondContact O-N 3.19Å; G92-S95 PolarHBondContact O-N 3.09Å; G92-L96 WeakPolarHBondContact O-CB 3.45Å; G92-L96 PolarHBondContact O-N 3.39Å
93	V	95.8	Very high	94.6	Very high	66 Å²	66	22 Å²	22	40%	0.4	12%	0.123	S	C	.	.	H	α-helix	trans	-64.7	-46	176.6	174.5	0	0	0	0	111.6	I89 A90 S95 L96 F97	I89-V93 WeakPolarHBondContact O-CG2 3.37Å; I89-V93 PolarHBondContact O-N 3.47Å; A90-V93 PolarHBondContact O-N 3.06Å; V93-S95 VanDerWaalsContact C-N 3.3Å; V93-S95 PolarHBondContact O-N 3.35Å; V93-L96 WeakPolarHBondContact O-CB 3.46Å; V93-L96 PolarHBondContact O-N 3.07Å; V93-F97 HydrophobicContact CG1-CE1 4.14Å; V93-F97 HydrophobicContact CG1-CZ 4.07Å; V93-F97 PolarHBondContact O-N 3.48Å
94	L	94.9	Very high	94.8	Very high	30 Å²	30	19.9 Å²	19.9	16%	0.157	11%	0.112	C	C	.	.	H	α-helix	trans	-62.1	-39.6	176.7	-71.7	172.7	0	0	0	111.5	A90 L96 F97 G98 F244 M248 V435 F436 T439	A90-L94 WeakPolarHBondContact O-CB 3.35Å; A90-L94 WeakPolarHBondContact O-CG 3.45Å; A90-L94 PolarHBondContact O-N 3.39Å; L94-L96 VanDerWaalsContact C-N 3.35Å; L94-F97 WeakPolarHBondContact O-CB 3.48Å; L94-F97 PolarHBondContact O-N 3.11Å; L94-G98 PolarHBondContact O-N 2.8Å; L94-F244 HydrophobicContact CD1-CD1 4.11Å; L94-F244 HydrophobicContact CD1-CE1 4Å; L94-M248 HydrophobicContact CB-CE 4.09Å; L94-M248 HydrophobicContact CB-SD 3.84Å; L94-M248 HydrophobicContact CD1-SD 4.38Å; L94-V435 HydrophobicContact CD2-CG1 4.41Å; L94-F436 WeakPolarHBondContact O-CD2 3.32Å; L94-F436 WeakPolarHBondContact O-CE2 3.2Å; L94-T439 HydrophobicContact CD1-CG2 4.04Å; L94-T439 HydrophobicContact CD2-CG2 4.42Å
95	S	94.5	Very high	94.8	Very high	0 Å²	0	20 Å²	20	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-67.6	-35.8	175.9	-62	0	0	0	0	112.1	C91 G92 V93 F97 G98 A99 Y251 M279	C91-S95 VanDerWaalsContact O-CB 3.23Å; C91-S95 WeakPolarHBondContact O-CB 3.4Å; C91-S95 PolarHBondContact O-N 2.8Å; C91-S95 PolarHBondContact O-OG 2.85Å; G92-S95 PolarHBondContact O-N 3.09Å; V93-S95 VanDerWaalsContact C-N 3.3Å; V93-S95 PolarHBondContact O-N 3.35Å; S95-F97 VanDerWaalsContact C-N 3.34Å; S95-F97 PolarHBondContact O-N 2.76Å; S95-G98 PolarHBondContact O-N 3.44Å; S95-A99 WeakPolarHBondContact O-CB 3.23Å; S95-A99 PolarHBondContact O-N 2.8Å; S95-Y251 WeakPolarHBondContact OG-CB 3.49Å; S95-M279 VanDerWaalsContact CB-CE 3.4Å
96	L	95.1	Very high	94.6	Very high	52 Å²	52	18.8 Å²	18.8	27%	0.272	11%	0.106	S	C	.	.	H	α-helix	trans	-61	-42.2	171.6	177.1	64.6	0	0	0	111.1	G92 V93 L94 G98 A99 L100 M279	G92-L96 WeakPolarHBondContact O-CB 3.45Å; G92-L96 PolarHBondContact O-N 3.39Å; V93-L96 WeakPolarHBondContact O-CB 3.46Å; V93-L96 PolarHBondContact O-N 3.07Å; L94-L96 VanDerWaalsContact C-N 3.35Å; L96-G98 VanDerWaalsContact C-N 3.34Å; L96-G98 PolarHBondContact O-N 3.19Å; L96-A99 PolarHBondContact O-N 3.47Å; L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CD2 4.29Å; L96-L100 HydrophobicContact CD1-CG 3.97Å; L96-L100 HydrophobicContact CG-CD1 3.97Å; L96-L100 HydrophobicContact CG-CG 4.21Å; L96-L100 WeakPolarHBondContact O-CB 3.37Å; L96-L100 VanDerWaalsContact O-CG 3.23Å; L96-L100 WeakPolarHBondContact O-CG 3.23Å; L96-L100 PolarHBondContact O-N 2.85Å; L96-M279 HydrophobicContact CB-CB 4.46Å; L96-M279 HydrophobicContact CD1-CB 3.9Å; L96-M279 HydrophobicContact CD1-CG 4.17Å
97	F	95.9	Very high	94.5	Very high	40 Å²	40	15.9 Å²	15.9	18%	0.175	9%	0.088	C	C	.	.	H	α-helix	trans	-58.6	-46	175.6	-71.4	-3.1	0	0	0	112.1	V93 L94 S95 A99 L100 C101 F431 I432 V435 F436	V93-F97 HydrophobicContact CG1-CE1 4.14Å; V93-F97 HydrophobicContact CG1-CZ 4.07Å; V93-F97 PolarHBondContact O-N 3.48Å; L94-F97 WeakPolarHBondContact O-CB 3.48Å; L94-F97 PolarHBondContact O-N 3.11Å; S95-F97 VanDerWaalsContact C-N 3.34Å; S95-F97 PolarHBondContact O-N 2.76Å; F97-A99 VanDerWaalsContact C-N 3.34Å; F97-A99 PolarHBondContact O-N 3.04Å; F97-L100 PolarHBondContact O-N 2.87Å; F97-C101 PolarHBondContact O-N 3.49Å; F97-C101 VanDerWaalsContact O-N 3.1Å; F97-C101 PolarHBondContact O-SG 3.07Å; F97-F431 HydrophobicContact CZ-CE2 4.2Å; F97-I432 HydrophobicContact CB-CG2 3.68Å; F97-I432 HydrophobicContact CD1-CD1 4.44Å; F97-I432 HydrophobicContact CD1-CG1 4.29Å; F97-I432 HydrophobicContact CD1-CG2 4.08Å; F97-I432 HydrophobicContact CE1-CG1 4.4Å; F97-I432 HydrophobicContact CG-CG2 3.91Å; F97-I432 WeakPolarHBondContact O-CG2 2.99Å; F97-V435 HydrophobicContact CD2-CB 4.46Å; F97-V435 HydrophobicContact CD2-CG1 4.09Å; F97-V435 HydrophobicContact CE2-CG1 4.14Å; F97-F436 HydrophobicContact CB-CB 4.07Å; F97-F436 HydrophobicContact CB-CD2 4.38Å; F97-F436 HydrophobicContact CB-CG 4.49Å
98	G	94.5	Very high	94.3	Very high	0 Å²	0	16.8 Å²	16.8	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-59.6	-44.9	173.9	0	0	0	0	0	112.6	L94 S95 L96 L100 C101 Y102 W254 F436	L94-G98 PolarHBondContact O-N 2.8Å; S95-G98 PolarHBondContact O-N 3.44Å; L96-G98 VanDerWaalsContact C-N 3.34Å; L96-G98 PolarHBondContact O-N 3.19Å; G98-L100 PolarHBondContact O-N 3.03Å; G98-C101 WeakPolarHBondContact O-CB 3.38Å; G98-C101 PolarHBondContact O-N 3.39Å; G98-Y102 WeakPolarHBondContact O-CD2 3.37Å; G98-Y102 PolarHBondContact O-N 3.24Å; G98-Y102 VanDerWaalsContact O-N 3.09Å; G98-W254 VanDerWaalsContact C-CH2 3.48Å; G98-W254 WeakPolarHBondContact O-CZ3 3.13Å; G98-F436 VanDerWaalsContact CA-CD1 3.4Å; G98-F436 VanDerWaalsContact CA-CZ 3.44Å
99	A	93.9	Very high	94.1	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-65.7	-38.5	-178.8	0	0	0	0	0	112.8	S95 L96 F97 Y102 A103 W254 I275 M279	S95-A99 WeakPolarHBondContact O-CB 3.23Å; S95-A99 PolarHBondContact O-N 2.8Å; L96-A99 PolarHBondContact O-N 3.47Å; F97-A99 VanDerWaalsContact C-N 3.34Å; F97-A99 PolarHBondContact O-N 3.04Å; A99-Y102 PolarHBondContact O-N 3.25Å; A99-A103 PolarHBondContact O-N 3.02Å; A99-W254 HydrophobicContact CB-CB 3.86Å; A99-W254 HydrophobicContact CB-CD2 3.73Å; A99-W254 HydrophobicContact CB-CE3 3.65Å; A99-W254 HydrophobicContact CB-CG 3.82Å; A99-W254 HydrophobicContact CB-CZ3 4.41Å; A99-I275 HydrophobicContact CB-CG2 3.26Å; A99-M279 HydrophobicContact CB-CG 4.08Å
100	L	95.2	Very high	93.5	Very high	23 Å²	23	18.1 Å²	18.1	12%	0.12	10%	0.098	C	C	.	.	H	α-helix	trans	-66.5	-35.7	174	-65.4	171.7	0	0	0	112.1	L96 F97 G98 Y102 A103 E104 F426 V428 I432	L96-L100 HydrophobicContact CD1-CD1 4.18Å; L96-L100 HydrophobicContact CD1-CD2 4.29Å; L96-L100 HydrophobicContact CD1-CG 3.97Å; L96-L100 HydrophobicContact CG-CD1 3.97Å; L96-L100 HydrophobicContact CG-CG 4.21Å; L96-L100 WeakPolarHBondContact O-CB 3.37Å; L96-L100 VanDerWaalsContact O-CG 3.23Å; L96-L100 WeakPolarHBondContact O-CG 3.23Å; L96-L100 PolarHBondContact O-N 2.85Å; F97-L100 PolarHBondContact O-N 2.87Å; G98-L100 PolarHBondContact O-N 3.03Å; L100-Y102 VanDerWaalsContact C-N 3.3Å; L100-Y102 PolarHBondContact O-N 3.45Å; L100-A103 WeakPolarHBondContact O-CB 3.17Å; L100-A103 PolarHBondContact O-N 3.5Å; L100-E104 PolarHBondContact O-N 2.87Å; L100-F426 HydrophobicContact CD2-CE1 4.41Å; L100-F426 HydrophobicContact CD2-CZ 3.98Å; L100-V428 HydrophobicContact CB-CG1 3.76Å; L100-I432 HydrophobicContact CD1-CD1 4.21Å
101	C	95.6	Very high	92.9	Very high	0 Å²	0	21.2 Å²	21.2	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-61.9	-40.5	172.7	-64.2	0	0	0	0	111.6	F97 G98 E104 L105 V409 L412 P433	F97-C101 PolarHBondContact O-N 3.49Å; F97-C101 VanDerWaalsContact O-N 3.1Å; F97-C101 PolarHBondContact O-SG 3.07Å; G98-C101 WeakPolarHBondContact O-CB 3.38Å; G98-C101 PolarHBondContact O-N 3.39Å; C101-E104 PolarHBondContact O-N 2.92Å; C101-L105 PolarHBondContact O-N 3.07Å; C101-V409 HydrophobicContact CB-CG1 4.48Å; C101-V409 HydrophobicContact CB-CG2 4.37Å; C101-L412 HydrophobicContact CB-CD2 3.81Å; C101-P433 WeakPolarHBondContact SG-CA 3.3Å; C101-P433 VanDerWaalsContact SG-CB 3.59Å
102	Y	93.7	Very high	92.1	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-73.1	-30.3	175.9	-85.7	-117.3	0	0	0	112.6	G98 A99 L100 E104 L105 G106 H115 Y118 W254 F255 N258 I405 V408 V409	G98-Y102 WeakPolarHBondContact O-CD2 3.37Å; G98-Y102 PolarHBondContact O-N 3.24Å; G98-Y102 VanDerWaalsContact O-N 3.09Å; A99-Y102 PolarHBondContact O-N 3.25Å; L100-Y102 VanDerWaalsContact C-N 3.3Å; L100-Y102 PolarHBondContact O-N 3.45Å; Y102-E104 VanDerWaalsContact C-N 3.32Å; Y102-L105 PolarHBondContact O-N 3.33Å; Y102-G106 PolarHBondContact O-N 3.22Å; Y102-H115 AromaticContact CE1-CE1 3.39Å; Y102-H115 WeakPolarHBondContact CE1-CE1 3.29Å; Y102-H115 AromaticContact CE1-ND1 3.29Å; Y102-H115 VanDerWaalsContact CE1-ND1 3.29Å; Y102-H115 WeakPolarHBondContact CE1-ND1 3.38Å; Y102-H115 AromaticContact CZ-CE1 3.51Å; Y102-H115 AromaticContact CZ-ND1 3.39Å; Y102-H115 PolarHBondContact OH-CE1 2.67Å; Y102-H115 PolarHBondContact OH-ND1 2.78Å; Y102-Y118 HydrophobicContact CD1-CD2 4.29Å; Y102-Y118 AromaticContact CD1-CE2 3.85Å; Y102-Y118 HydrophobicContact CD1-CE2 3.85Å; Y102-Y118 HydrophobicContact CE1-CD2 4.2Å; Y102-Y118 HydrophobicContact CE1-CE2 4.16Å; Y102-W254 HydrophobicContact CD1-CZ3 4.04Å; Y102-W254 AromaticContact CD2-CH2 3.54Å; Y102-W254 HydrophobicContact CD2-CH2 3.54Å; Y102-W254 AromaticContact CD2-CZ3 3.28Å; Y102-W254 HydrophobicContact CD2-CZ3 3.28Å; Y102-W254 HydrophobicContact CE1-CZ3 4.43Å; Y102-W254 AromaticContact CE2-CH2 3.55Å; Y102-W254 HydrophobicContact CE2-CH2 3.55Å; Y102-W254 AromaticContact CE2-CZ3 3.72Å; Y102-W254 HydrophobicContact CE2-CZ3 3.72Å; Y102-W254 HydrophobicContact CG-CE3 4.41Å; Y102-W254 HydrophobicContact CG-CH2 4.16Å; Y102-W254 AromaticContact CG-CZ3 3.44Å; Y102-W254 HydrophobicContact CG-CZ3 3.44Å; Y102-W254 VanDerWaalsContact CG-CZ3 3.44Å; Y102-F255 HydrophobicContact CD1-CB 3.79Å; Y102-F255 HydrophobicContact CE1-CB 3.89Å; Y102-F255 HydrophobicContact CG-CB 4.46Å; Y102-N258 HydrophobicContact CD1-CB 4.38Å; Y102-N258 PolarHBondContact O-ND2 3.33Å; Y102-I405 HydrophobicContact CE2-CG2 4.37Å; Y102-V408 HydrophobicContact CE1-CG1 4.01Å; Y102-V408 HydrophobicContact CE2-CB 4.44Å; Y102-V408 HydrophobicContact CE2-CG1 3.84Å; Y102-V408 VanDerWaalsContact CZ-CG1 3.47Å; Y102-V408 VanDerWaalsContact OH-CB 3.31Å; Y102-V408 WeakPolarHBondContact OH-CB 3.43Å; Y102-V408 VanDerWaalsContact OH-CG1 3.31Å; Y102-V408 WeakPolarHBondContact OH-CG1 3.11Å; Y102-V409 HydrophobicContact CE2-CG2 4.06Å
103	A	93.6	Very high	91.2	Very high	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.109	C	C	.	.	H	α-helix	trans	-61.3	-42.6	170.9	0	0	0	0	0	111	A99 L100 G106 T107 V271 P272 I275 F426	A99-A103 PolarHBondContact O-N 3.02Å; L100-A103 WeakPolarHBondContact O-CB 3.17Å; L100-A103 PolarHBondContact O-N 3.5Å; A103-G106 PolarHBondContact O-N 3.48Å; A103-T107 WeakPolarHBondContact O-CB 3.22Å; A103-T107 VanDerWaalsContact O-CG2 3.25Å; A103-T107 WeakPolarHBondContact O-CG2 3.39Å; A103-T107 PolarHBondContact O-N 2.96Å; A103-T107 PolarHBondContact O-OG1 3.48Å; A103-V271 HydrophobicContact CB-CG1 4.39Å; A103-P272 HydrophobicContact CB-CB 4.21Å; A103-P272 HydrophobicContact CB-CG 4.25Å; A103-I275 HydrophobicContact CB-CD1 3.98Å; A103-F426 HydrophobicContact CB-CD1 3.97Å; A103-F426 HydrophobicContact CB-CE1 3.82Å
104	E	94.7	Very high	90.7	Very high	0 Å²	0	18.5 Å²	18.5	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-62.2	-49.3	173.1	175.7	166.6	167.9	0	0	111.7	L100 C101 Y102 G106 T107 C108 L412 R416 R424 F426 V428	L100-E104 PolarHBondContact O-N 2.87Å; C101-E104 PolarHBondContact O-N 2.92Å; Y102-E104 VanDerWaalsContact C-N 3.32Å; E104-G106 VanDerWaalsContact C-N 3.35Å; E104-G106 PolarHBondContact O-N 2.9Å; E104-T107 PolarHBondContact O-N 2.96Å; E104-T107 PolarHBondContact O-OG1 3.3Å; E104-C108 WeakPolarHBondContact O-CB 3.27Å; E104-C108 PolarHBondContact O-N 2.98Å; E104-C108 PolarHBondContact O-SG 3.22Å; E104-L412 HydrophobicContact CB-CD1 4.48Å; E104-L412 HydrophobicContact CG-CD1 3.79Å; E104-R416 IonicContact OE1-CZ 3.68Å; E104-R416 VanDerWaalsContact OE1-CZ 3.31Å; E104-R416 IonicContact OE1-NE 2.75Å; E104-R416 PolarHBondContact OE1-NE 2.93Å; E104-R416 IonicContact OE1-NH2 2.64Å; E104-R416 PolarHBondContact OE1-NH2 3.21Å; E104-R416 IonicContact OE2-CZ 2.65Å; E104-R416 IonicContact OE2-NH2 3.31Å; E104-R416 PolarHBondContact OE2-NH2 3.45Å; E104-R424 WeakPolarHBondContact OE1-CD 3.29Å; E104-R424 IonicContact OE1-NE 3.76Å; E104-F426 HydrophobicContact CB-CD1 4.2Å; E104-F426 WeakPolarHBondContact CG-O 3.49Å; E104-V428 WeakPolarHBondContact OE2-CG2 3.47Å; E104-V428 PolarHBondContact OE2-N 2.93Å
105	L	93.4	Very high	90.5	Very high	3 Å²	3	17.2 Å²	17.2	2%	0.016	8%	0.083	C	C	.	.	H	α-helix	trans	-60.1	-42.2	177.9	-75.1	171.7	0	0	0	112.8	C101 Y102 C108 I109 Y118 V408 L412 L415	C101-L105 PolarHBondContact O-N 3.07Å; Y102-L105 PolarHBondContact O-N 3.33Å; L105-C108 PolarHBondContact O-N 3.03Å; L105-I109 HydrophobicContact CD2-CD1 4.37Å; L105-I109 WeakPolarHBondContact O-CB 3.29Å; L105-I109 PolarHBondContact O-N 3.22Å; L105-Y118 HydrophobicContact CB-CD1 4.13Å; L105-Y118 HydrophobicContact CB-CD2 4.01Å; L105-Y118 HydrophobicContact CB-CE1 4.04Å; L105-Y118 HydrophobicContact CB-CE2 3.89Å; L105-Y118 HydrophobicContact CB-CG 4.15Å; L105-Y118 HydrophobicContact CD1-CD2 3.83Å; L105-Y118 HydrophobicContact CD1-CE2 4.39Å; L105-Y118 HydrophobicContact CD1-CG 4.08Å; L105-V408 HydrophobicContact CD1-CG1 3.41Å; L105-V408 VanDerWaalsContact CD1-CG1 3.41Å; L105-L412 HydrophobicContact CD1-CB 4.13Å; L105-L412 HydrophobicContact CD2-CB 3.94Å; L105-L412 HydrophobicContact CD2-CD1 3.76Å; L105-L412 HydrophobicContact CD2-CG 4.41Å; L105-L412 HydrophobicContact CG-CB 4.04Å; L105-L412 HydrophobicContact CG-CD1 3.97Å; L105-L412 HydrophobicContact CG-CD2 4.48Å; L105-L412 HydrophobicContact CG-CG 4.38Å; L105-L415 HydrophobicContact CD2-CD1 4.23Å
106	G	90.3	Very high	90.3	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-71.5	-27.9	-179.9	0	0	0	0	0	114.2	Y102 A103 E104 Y118	Y102-G106 PolarHBondContact O-N 3.22Å; A103-G106 PolarHBondContact O-N 3.48Å; E104-G106 VanDerWaalsContact C-N 3.35Å; E104-G106 PolarHBondContact O-N 2.9Å; G106-Y118 WeakPolarHBondContact CA-OH 3.14Å; G106-Y118 PolarHBondContact N-OH 3.06Å
107	T	91.5	Very high	90	Very high	1 Å²	1	15.3 Å²	15.3	1%	0.006	7%	0.074	C	C	.	.	H	α-helix	trans	-80.7	-29.4	173.7	54.7	0	0	0	0	112.5	A103 E104 K110 P272 F426	A103-T107 WeakPolarHBondContact O-CB 3.22Å; A103-T107 VanDerWaalsContact O-CG2 3.25Å; A103-T107 WeakPolarHBondContact O-CG2 3.39Å; A103-T107 PolarHBondContact O-N 2.96Å; A103-T107 PolarHBondContact O-OG1 3.48Å; E104-T107 PolarHBondContact O-N 2.96Å; E104-T107 PolarHBondContact O-OG1 3.3Å; T107-K110 WeakPolarHBondContact O-CE 3.22Å; T107-P272 HydrophobicContact CG2-CG 3.89Å; T107-F426 HydrophobicContact CG2-CB 4.12Å
108	C	90.9	Very high	89.9	Confident	23 Å²	23	13.6 Å²	13.6	16%	0.155	7%	0.066	C	C	.	.	H	α-helix	trans	-78.3	-46.9	174.8	-62.7	0	0	0	0	112.5	E104 L105 L422 R424	E104-C108 WeakPolarHBondContact O-CB 3.27Å; E104-C108 PolarHBondContact O-N 2.98Å; E104-C108 PolarHBondContact O-SG 3.22Å; L105-C108 PolarHBondContact O-N 3.03Å; C108-L422 HydrophobicContact CB-CD2 4.01Å; C108-R424 VanDerWaalsContact SG-CG 3.54Å
109	I	89.8	Confident	89.9	Confident	13 Å²	13	13.6 Å²	13.6	7%	0.067	7%	0.066	C	C	.	.			trans	-112.4	89.9	-175.2	-54.3	166.3	0	0	0	108	L105 K111 T117 Y118 E121 L415	L105-I109 HydrophobicContact CD2-CD1 4.37Å; L105-I109 WeakPolarHBondContact O-CB 3.29Å; L105-I109 PolarHBondContact O-N 3.22Å; I109-K111 HydrophobicContact CG2-CB 4.32Å; I109-K111 PolarHBondContact O-N 3.31Å; I109-T117 HydrophobicContact CG2-CG2 4.06Å; I109-Y118 HydrophobicContact CB-CD1 4.14Å; I109-Y118 HydrophobicContact CB-CE1 4.01Å; I109-Y118 HydrophobicContact CD1-CD1 3.91Å; I109-Y118 HydrophobicContact CG2-CD1 4.32Å; I109-Y118 HydrophobicContact CG2-CE1 4.35Å; I109-E121 HydrophobicContact CD1-CB 3.83Å; I109-E121 HydrophobicContact CD1-CG 3.76Å; I109-E121 HydrophobicContact CG1-CG 4.29Å; I109-L415 HydrophobicContact CD1-CD1 4.18Å
110	K	84.6	Confident	89.8	Confident	98 Å²	98	15.2 Å²	15.2	43%	0.426	7%	0.074	S	C	.	.			trans	-79.2	23.5	-174.2	-58.7	175.1	-177	172.5	0	114.1	T107 E262 P267 E268	T107-K110 WeakPolarHBondContact O-CE 3.22Å; K110-E262 VanDerWaalsContact O-CG 3.29Å; K110-E262 WeakPolarHBondContact O-CG 3.37Å; K110-P267 HydrophobicContact CD-CG 4.37Å; K110-E268 IonicContact NZ-OE1 2.98Å; K110-E268 PolarHBondContact NZ-OE1 3.4Å
111	K	82.7	Confident	89.7	Confident	95 Å²	95	17.2 Å²	17.2	41%	0.413	8%	0.083	S	C	.	.			trans	-92.6	143.6	176.8	-68.6	-178.5	178.8	-178.4	0	109.7	I109 T117 E262	I109-K111 HydrophobicContact CG2-CB 4.32Å; I109-K111 PolarHBondContact O-N 3.31Å; K111-T117 HydrophobicContact CB-CG2 3.54Å; K111-T117 HydrophobicContact CD-CG2 4Å; K111-T117 HydrophobicContact CG-CG2 4.4Å; K111-E262 WeakPolarHBondContact CA-OE1 3.24Å
112	S	77.2	Confident	89.6	Confident	7 Å²	7	17.8 Å²	17.8	5%	0.049	9%	0.087	C	C	.	.	S	Bend	trans	-70.2	160.4	173.6	-67	0	0	0	0	111	T117 F259 E262	S112-T117 PolarHBondContact O-OG1 3.5Å; S112-F259 WeakPolarHBondContact CB-O 3.34Å; S112-E262 VanDerWaalsContact CB-CD 3.47Å; S112-E262 VanDerWaalsContact CB-OE2 3.27Å; S112-E262 WeakPolarHBondContact CB-OE2 3.45Å; S112-E262 PolarHBondContact N-OE1 2.88Å; S112-E262 VanDerWaalsContact OG-CB 3.22Å; S112-E262 WeakPolarHBondContact OG-CB 3.35Å; S112-E262 WeakPolarHBondContact OG-CG 3.45Å; S112-E262 PolarHBondContact OG-OE2 3.37Å
113	G	77.2	Confident	89.7	Confident	3 Å²	3	21.1 Å²	21.1	3%	0.031	10%	0.102	C	C	.	.	S	Bend	trans	113	-5.2	177.8	0	0	0	0	0	115.8	H115 Y116 T117 F259	G113-H115 PolarHBondContact O-N 2.91Å; G113-Y116 PolarHBondContact O-N 3.34Å; G113-T117 WeakPolarHBondContact CA-OG1 3.46Å; G113-F259 PolarHBondContact N-O 3.31Å; G113-F259 VanDerWaalsContact O-CE1 3.28Å; G113-F259 WeakPolarHBondContact O-CE1 3.39Å
114	G	86.1	Confident	89.6	Confident	0 Å²	0	22 Å²	22	0%	0	11%	0.111	C	C	.	.	T	Hydrogen-bonded Turn	trans	55.6	-122.6	170.5	0	0	0	0	0	113.4	Y116 T117 Y118 N258	G114-Y116 PolarHBondContact O-N 3.49Å; G114-T117 PolarHBondContact O-N 3.47Å; G114-Y118 VanDerWaalsContact O-CD2 3.24Å; G114-Y118 WeakPolarHBondContact O-CD2 3.34Å; G114-Y118 VanDerWaalsContact O-CG 3.26Å; G114-Y118 PolarHBondContact O-N 3.02Å; G114-Y118 VanDerWaalsContact O-N 3.11Å; G114-N258 PolarHBondContact N-O 2.82Å
115	H	89.9	Confident	89.4	Confident	4 Å²	4	25.1 Å²	25.1	2%	0.019	13%	0.131	C	C	.	.	H	α-helix	trans	-51.4	-42.4	-177.5	-55.1	-60.5	0	0	0	113.4	Y102 G113 Y118 I119 R131 F255 F259 V408	Y102-H115 AromaticContact CE1-CE1 3.39Å; Y102-H115 WeakPolarHBondContact CE1-CE1 3.29Å; Y102-H115 AromaticContact CE1-ND1 3.29Å; Y102-H115 VanDerWaalsContact CE1-ND1 3.29Å; Y102-H115 WeakPolarHBondContact CE1-ND1 3.38Å; Y102-H115 AromaticContact CZ-CE1 3.51Å; Y102-H115 AromaticContact CZ-ND1 3.39Å; Y102-H115 PolarHBondContact OH-CE1 2.67Å; Y102-H115 PolarHBondContact OH-ND1 2.78Å; G113-H115 PolarHBondContact O-N 2.91Å; H115-Y118 PolarHBondContact O-N 3.24Å; H115-I119 WeakPolarHBondContact O-CG1 3.39Å; H115-I119 PolarHBondContact O-N 3.36Å; H115-R131 PolarHBondContact CD2-NH2 3.3Å; H115-F255 AromaticContact CE1-CG 3.77Å; H115-F255 AromaticContact NE2-CD2 3.5Å; H115-F255 WeakPolarHBondContact NE2-CD2 3.48Å; H115-F255 AromaticContact NE2-CE2 3.71Å; H115-F255 AromaticContact NE2-CG 3.74Å; H115-F259 AromaticContact CD2-CE2 3.81Å; H115-F259 AromaticContact CD2-CZ 3.46Å; H115-F259 VanDerWaalsContact CD2-CZ 3.46Å; H115-F259 WeakPolarHBondContact CD2-CZ 3.43Å; H115-F259 AromaticContact NE2-CE2 3.94Å; H115-V408 HydrophobicContact CB-CG2 4.06Å
116	Y	89.8	Confident	89.4	Confident	2 Å²	2	28.2 Å²	28.2	1%	0.008	15%	0.146	C	C	.	.	H	α-helix	trans	-59.9	-51.2	-177.8	170.5	-104.7	0	0	0	111.2	G113 G114 Y118 I119 M120 A128 L132 V349 E353 Q355	G113-Y116 PolarHBondContact O-N 3.34Å; G114-Y116 PolarHBondContact O-N 3.49Å; Y116-Y118 PolarHBondContact O-N 3.47Å; Y116-I119 PolarHBondContact O-N 3.26Å; Y116-M120 HydrophobicContact CE1-CE 4.39Å; Y116-M120 HydrophobicContact CE2-CE 4.36Å; Y116-M120 WeakPolarHBondContact O-CB 3.28Å; Y116-M120 PolarHBondContact O-N 3.03Å; Y116-M120 VanDerWaalsContact OH-CE 3.23Å; Y116-M120 WeakPolarHBondContact OH-CE 3.31Å; Y116-A128 HydrophobicContact CD2-CB 3.95Å; Y116-A128 WeakPolarHBondContact CD2-O 3.37Å; Y116-A128 HydrophobicContact CE2-CB 3.68Å; Y116-L132 HydrophobicContact CD2-CB 3.99Å; Y116-L132 HydrophobicContact CE2-CB 4.13Å; Y116-L132 HydrophobicContact CE2-CD2 4.09Å; Y116-V349 HydrophobicContact CD1-CG1 4.2Å; Y116-V349 HydrophobicContact CE1-CG1 4.28Å; Y116-E353 HydrophobicContact CE1-CB 4.43Å; Y116-E353 HydrophobicContact CE1-CG 4.09Å; Y116-E353 WeakPolarHBondContact OH-CB 3.35Å; Y116-Q355 VanDerWaalsContact CZ-OE1 3.3Å; Y116-Q355 WeakPolarHBondContact OH-CG 3.36Å; Y116-Q355 PolarHBondContact OH-OE1 3.18Å
117	T	89.9	Confident	89.5	Confident	10 Å²	10	31.3 Å²	31.3	6%	0.061	16%	0.161	C	C	.	.	H	α-helix	trans	-68.7	-35.1	-176.8	-50.9	0	0	0	0	112.2	I109 K111 S112 G113 G114 M120 E121	I109-T117 HydrophobicContact CG2-CG2 4.06Å; K111-T117 HydrophobicContact CB-CG2 3.54Å; K111-T117 HydrophobicContact CD-CG2 4Å; K111-T117 HydrophobicContact CG-CG2 4.4Å; S112-T117 PolarHBondContact O-OG1 3.5Å; G113-T117 WeakPolarHBondContact CA-OG1 3.46Å; G114-T117 PolarHBondContact O-N 3.47Å; T117-M120 WeakPolarHBondContact O-CB 3.48Å; T117-M120 PolarHBondContact O-N 3.5Å; T117-E121 PolarHBondContact O-N 3.2Å
118	Y	92.8	Very high	89.6	Confident	3 Å²	3	31.3 Å²	31.3	1%	0.012	16%	0.161	C	C	.	.	H	α-helix	trans	-68.6	-41.1	176	-57.1	-27.8	0	0	0	112.3	Y102 L105 G106 I109 G114 H115 Y116 M120 E121 A122 N258 V408	Y102-Y118 HydrophobicContact CD1-CD2 4.29Å; Y102-Y118 AromaticContact CD1-CE2 3.85Å; Y102-Y118 HydrophobicContact CD1-CE2 3.85Å; Y102-Y118 HydrophobicContact CE1-CD2 4.2Å; Y102-Y118 HydrophobicContact CE1-CE2 4.16Å; L105-Y118 HydrophobicContact CB-CD1 4.13Å; L105-Y118 HydrophobicContact CB-CD2 4.01Å; L105-Y118 HydrophobicContact CB-CE1 4.04Å; L105-Y118 HydrophobicContact CB-CE2 3.89Å; L105-Y118 HydrophobicContact CB-CG 4.15Å; L105-Y118 HydrophobicContact CD1-CD2 3.83Å; L105-Y118 HydrophobicContact CD1-CE2 4.39Å; L105-Y118 HydrophobicContact CD1-CG 4.08Å; G106-Y118 WeakPolarHBondContact CA-OH 3.14Å; G106-Y118 PolarHBondContact N-OH 3.06Å; I109-Y118 HydrophobicContact CB-CD1 4.14Å; I109-Y118 HydrophobicContact CB-CE1 4.01Å; I109-Y118 HydrophobicContact CD1-CD1 3.91Å; I109-Y118 HydrophobicContact CG2-CD1 4.32Å; I109-Y118 HydrophobicContact CG2-CE1 4.35Å; G114-Y118 VanDerWaalsContact O-CD2 3.24Å; G114-Y118 WeakPolarHBondContact O-CD2 3.34Å; G114-Y118 VanDerWaalsContact O-CG 3.26Å; G114-Y118 PolarHBondContact O-N 3.02Å; G114-Y118 VanDerWaalsContact O-N 3.11Å; H115-Y118 PolarHBondContact O-N 3.24Å; Y116-Y118 PolarHBondContact O-N 3.47Å; Y118-M120 VanDerWaalsContact C-N 3.35Å; Y118-E121 PolarHBondContact O-N 2.93Å; Y118-A122 WeakPolarHBondContact O-CB 3.3Å; Y118-A122 PolarHBondContact O-N 3.18Å; Y118-A122 VanDerWaalsContact O-N 3.09Å; Y118-N258 HydrophobicContact CE2-CB 4.14Å; Y118-N258 WeakPolarHBondContact OH-CB 3.13Å; Y118-N258 PolarHBondContact OH-ND2 3.35Å; Y118-V408 HydrophobicContact CD2-CG1 3.91Å; Y118-V408 HydrophobicContact CG-CG1 4.44Å
119	I	94.6	Very high	89.7	Confident	0 Å²	0	30.3 Å²	30.3	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-67.9	-38.3	174.6	-66.7	178.4	0	0	0	110.6	H115 Y116 E121 A122 F123 G124 M127 A128 R131 F404 V407 V408	H115-I119 WeakPolarHBondContact O-CG1 3.39Å; H115-I119 PolarHBondContact O-N 3.36Å; Y116-I119 PolarHBondContact O-N 3.26Å; I119-E121 PolarHBondContact O-N 3.42Å; I119-A122 PolarHBondContact O-N 3.43Å; I119-F123 HydrophobicContact CG2-CB 4.45Å; I119-F123 HydrophobicContact CG2-CD2 4.22Å; I119-F123 PolarHBondContact O-N 3.31Å; I119-G124 PolarHBondContact O-N 3.04Å; I119-M127 VanDerWaalsContact CG2-C 3.49Å; I119-M127 HydrophobicContact CG2-CB 3.61Å; I119-A128 HydrophobicContact CG2-CB 4.34Å; I119-R131 HydrophobicContact CD1-CB 3.84Å; I119-R131 HydrophobicContact CD1-CG 3.82Å; I119-F404 HydrophobicContact CD1-CD1 4.16Å; I119-V407 HydrophobicContact CD1-CG1 4.08Å; I119-V407 HydrophobicContact CG1-CG1 4.3Å; I119-V408 HydrophobicContact CD1-CG2 3.89Å; I119-V408 HydrophobicContact CG1-CG2 3.7Å
120	M	92.3	Very high	89.9	Confident	34 Å²	34	30.2 Å²	30.2	17%	0.167	15%	0.153	C	C	.	.	H	α-helix	trans	-57.1	-47.6	175	-180	67.2	84.7	0	0	111.6	Y116 T117 Y118 G124 P125 A128	Y116-M120 HydrophobicContact CE1-CE 4.39Å; Y116-M120 HydrophobicContact CE2-CE 4.36Å; Y116-M120 WeakPolarHBondContact O-CB 3.28Å; Y116-M120 PolarHBondContact O-N 3.03Å; Y116-M120 VanDerWaalsContact OH-CE 3.23Å; Y116-M120 WeakPolarHBondContact OH-CE 3.31Å; T117-M120 WeakPolarHBondContact O-CB 3.48Å; T117-M120 PolarHBondContact O-N 3.5Å; Y118-M120 VanDerWaalsContact C-N 3.35Å; M120-G124 WeakPolarHBondContact O-CA 3.46Å; M120-G124 PolarHBondContact O-N 3.25Å; M120-P125 HydrophobicContact CE-CB 4.25Å; M120-P125 WeakPolarHBondContact SD-CA 3.31Å; M120-P125 HydrophobicContact SD-CB 3.92Å; M120-P125 HydrophobicContact SD-CG 3.8Å; M120-A128 HydrophobicContact CB-CB 3.79Å; M120-A128 HydrophobicContact CE-CB 3.89Å; M120-A128 HydrophobicContact SD-CB 4.09Å
121	E	92.3	Very high	90.3	Very high	66 Å²	66	26 Å²	26	31%	0.308	14%	0.135	S	C	.	.	H	α-helix	trans	-73	-30.3	-178	-170	59.9	-143.4	0	0	113.3	I109 T117 Y118 I119 K419	I109-E121 HydrophobicContact CD1-CB 3.83Å; I109-E121 HydrophobicContact CD1-CG 3.76Å; I109-E121 HydrophobicContact CG1-CG 4.29Å; T117-E121 PolarHBondContact O-N 3.2Å; Y118-E121 PolarHBondContact O-N 2.93Å; I119-E121 PolarHBondContact O-N 3.42Å; E121-K419 PolarHBondContact O-NZ 3.26Å; E121-K419 IonicContact OE1-NZ 3Å; E121-K419 PolarHBondContact OE1-NZ 2.87Å
122	A	94.3	Very high	90.7	Very high	11 Å²	11	21.6 Å²	21.6	9%	0.091	12%	0.116	C	C	.	.	H	α-helix	trans	-86.9	-48.4	-178.1	0	0	0	0	0	113.4	Y118 I119 Y414 L415	Y118-A122 WeakPolarHBondContact O-CB 3.3Å; Y118-A122 PolarHBondContact O-N 3.18Å; Y118-A122 VanDerWaalsContact O-N 3.09Å; I119-A122 PolarHBondContact O-N 3.43Å; A122-Y414 WeakPolarHBondContact O-CE1 3.28Å; A122-L415 HydrophobicContact CB-CD1 4.09Å; A122-L415 HydrophobicContact CB-CD2 4.45Å; A122-L415 HydrophobicContact CB-CG 4.06Å
123	F	95.1	Very high	91.4	Very high	71 Å²	71	23.4 Å²	23.4	31%	0.311	12%	0.122	S	C	.	.	H	α-helix	trans	-119	-5.3	-169.8	-57.9	-67.6	0	0	0	113.9	I119 M127 V407 L410 Y414	I119-F123 HydrophobicContact CG2-CB 4.45Å; I119-F123 HydrophobicContact CG2-CD2 4.22Å; I119-F123 PolarHBondContact O-N 3.31Å; F123-M127 HydrophobicContact CB-CB 3.83Å; F123-M127 HydrophobicContact CB-CG 3.91Å; F123-V407 HydrophobicContact CD2-CG1 4.06Å; F123-V407 HydrophobicContact CE2-CG1 3.72Å; F123-V407 WeakPolarHBondContact CE2-O 3.32Å; F123-L410 HydrophobicContact CZ-CG 4.48Å; F123-Y414 HydrophobicContact CE1-CD1 4.37Å; F123-Y414 HydrophobicContact CE1-CG 4.41Å
124	G	92.3	Very high	92.1	Very high	19 Å²	19	23.3 Å²	23.3	20%	0.196	12%	0.12	C	C	.	.			trans	88.8	-176.9	175.5	0	0	0	0	0	115.6	I119 M120 Q126 A128	I119-G124 PolarHBondContact O-N 3.04Å; M120-G124 WeakPolarHBondContact O-CA 3.46Å; M120-G124 PolarHBondContact O-N 3.25Å; G124-Q126 PolarHBondContact O-N 2.91Å; G124-A128 PolarHBondContact O-N 3.09Å
125	P	91.1	Very high	92.3	Very high	65 Å²	65	23.4 Å²	23.4	42%	0.422	12%	0.121	S	C	.	.	H	α-helix	trans	-64.6	-35.4	-166.7	-24.2	33.8	0	0	0	115.5	M120 A128 F129 Q355 Y469	M120-P125 HydrophobicContact CE-CB 4.25Å; M120-P125 WeakPolarHBondContact SD-CA 3.31Å; M120-P125 HydrophobicContact SD-CB 3.92Å; M120-P125 HydrophobicContact SD-CG 3.8Å; P125-A128 PolarHBondContact O-N 2.93Å; P125-F129 WeakPolarHBondContact O-CB 3.5Å; P125-F129 PolarHBondContact O-N 3.02Å; P125-Q355 PolarHBondContact O-NE2 2.71Å; P125-Y469 HydrophobicContact CB-CE2 4.36Å
126	Q	92.3	Very high	92.2	Very high	67 Å²	67	24.2 Å²	24.2	31%	0.313	13%	0.125	S	C	.	.	H	α-helix	trans	-64.9	-49.4	-178	-175.9	-176.1	-11.5	0	0	111.5	G124 A128 F129 I130 Y469	G124-Q126 PolarHBondContact O-N 2.91Å; Q126-A128 VanDerWaalsContact C-N 3.32Å; Q126-A128 PolarHBondContact O-N 3.35Å; Q126-F129 PolarHBondContact O-N 3.04Å; Q126-I130 HydrophobicContact CG-CD1 4.3Å; Q126-I130 WeakPolarHBondContact O-CG1 3.35Å; Q126-I130 PolarHBondContact O-N 3.45Å; Q126-Y469 HydrophobicContact CB-CD1 4.26Å; Q126-Y469 HydrophobicContact CB-CE1 3.94Å; Q126-Y469 HydrophobicContact CB-CE2 4.48Å; Q126-Y469 HydrophobicContact CG-CD1 3.95Å; Q126-Y469 HydrophobicContact CG-CE1 4.11Å; Q126-Y469 HydrophobicContact CG-CG 4.36Å
127	M	93.9	Very high	92.1	Very high	66 Å²	66	25.6 Å²	25.6	33%	0.325	13%	0.132	S	C	.	.	H	α-helix	trans	-66.8	-36.2	178.7	-72.4	-57.3	-62.1	0	0	112	I119 F123 F129 I130 R131	I119-M127 VanDerWaalsContact CG2-C 3.49Å; I119-M127 HydrophobicContact CG2-CB 3.61Å; F123-M127 HydrophobicContact CB-CB 3.83Å; F123-M127 HydrophobicContact CB-CG 3.91Å; M127-F129 VanDerWaalsContact C-N 3.31Å; M127-F129 PolarHBondContact O-N 3.24Å; M127-I130 PolarHBondContact O-N 3.41Å; M127-I130 HydrophobicContact SD-CD1 3.93Å; M127-R131 PolarHBondContact O-N 3.49Å; M127-R131 VanDerWaalsContact O-N 3.09Å
128	A	92.8	Very high	92.1	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-62.2	-40.6	174.4	0	0	0	0	0	111.5	Y116 I119 M120 G124 P125 Q126 R131 L132	Y116-A128 HydrophobicContact CD2-CB 3.95Å; Y116-A128 WeakPolarHBondContact CD2-O 3.37Å; Y116-A128 HydrophobicContact CE2-CB 3.68Å; I119-A128 HydrophobicContact CG2-CB 4.34Å; M120-A128 HydrophobicContact CB-CB 3.79Å; M120-A128 HydrophobicContact CE-CB 3.89Å; M120-A128 HydrophobicContact SD-CB 4.09Å; G124-A128 PolarHBondContact O-N 3.09Å; P125-A128 PolarHBondContact O-N 2.93Å; Q126-A128 VanDerWaalsContact C-N 3.32Å; Q126-A128 PolarHBondContact O-N 3.35Å; A128-R131 WeakPolarHBondContact O-CB 3.46Å; A128-R131 PolarHBondContact O-N 2.89Å; A128-L132 WeakPolarHBondContact O-CB 3.37Å; A128-L132 PolarHBondContact O-N 3.01Å
129	F	92.6	Very high	92	Very high	3 Å²	3	25.6 Å²	25.6	1%	0.013	13%	0.132	C	C	.	.	H	α-helix	trans	-67.1	-43.7	176.1	-176.1	-93.9	0	0	0	112.7	P125 Q126 M127 R131 L132 W133 Q355 G465 A468 Y469 I473	P125-F129 WeakPolarHBondContact O-CB 3.5Å; P125-F129 PolarHBondContact O-N 3.02Å; Q126-F129 PolarHBondContact O-N 3.04Å; M127-F129 VanDerWaalsContact C-N 3.31Å; M127-F129 PolarHBondContact O-N 3.24Å; F129-R131 PolarHBondContact O-N 2.9Å; F129-L132 HydrophobicContact CD2-CD2 4.19Å; F129-L132 CarbonylContact O-C 3.55Å; F129-L132 WeakPolarHBondContact O-CB 3.39Å; F129-L132 PolarHBondContact O-N 3.27Å; F129-L132 VanDerWaalsContact O-N 3.08Å; F129-W133 HydrophobicContact CD1-CB 4.45Å; F129-W133 HydrophobicContact CE1-CB 4.23Å; F129-W133 HydrophobicContact CE1-CD2 4.24Å; F129-W133 AromaticContact CE1-CE3 3.93Å; F129-W133 HydrophobicContact CE1-CE3 3.93Å; F129-W133 HydrophobicContact CE1-CG 4.42Å; F129-W133 HydrophobicContact CZ-CD2 4.39Å; F129-W133 AromaticContact CZ-CE3 3.63Å; F129-W133 HydrophobicContact CZ-CE3 3.63Å; F129-W133 HydrophobicContact CZ-CZ3 4.13Å; F129-W133 VanDerWaalsContact O-CB 3.29Å; F129-W133 WeakPolarHBondContact O-CB 3.29Å; F129-W133 PolarHBondContact O-N 2.9Å; F129-Q355 HydrophobicContact CD2-CB 4.14Å; F129-Q355 WeakPolarHBondContact CE2-O 3.24Å; F129-G465 WeakPolarHBondContact CD1-O 3.45Å; F129-G465 VanDerWaalsContact CE1-O 3.27Å; F129-G465 WeakPolarHBondContact CE1-O 3.32Å; F129-A468 HydrophobicContact CE1-CB 3.93Å; F129-A468 HydrophobicContact CZ-CB 4.26Å; F129-Y469 HydrophobicContact CB-CD2 3.49Å; F129-Y469 VanDerWaalsContact CB-CD2 3.49Å; F129-Y469 HydrophobicContact CB-CE2 4.12Å; F129-Y469 HydrophobicContact CB-CG 4.39Å; F129-Y469 AromaticContact CD1-CD2 3.94Å; F129-Y469 HydrophobicContact CD1-CD2 3.94Å; F129-Y469 HydrophobicContact CD1-CG 4.22Å; F129-Y469 HydrophobicContact CD2-CD2 4.3Å; F129-Y469 AromaticContact CG-CD2 3.64Å; F129-Y469 HydrophobicContact CG-CD2 3.64Å; F129-Y469 HydrophobicContact CG-CG 4.37Å; F129-I473 HydrophobicContact CB-CD1 4.5Å; F129-I473 HydrophobicContact CD2-CD1 3.26Å; F129-I473 HydrophobicContact CE2-CD1 3.48Å; F129-I473 VanDerWaalsContact CE2-CD1 3.48Å; F129-I473 HydrophobicContact CG-CD1 3.93Å; F129-I473 HydrophobicContact CZ-CD1 4.29Å
130	I	94.1	Very high	91.6	Very high	11 Å²	11	26.5 Å²	26.5	6%	0.056	14%	0.136	C	C	.	.	H	α-helix	trans	-57.9	-42.6	177.1	-66.6	164.2	0	0	0	110.4	Q126 M127 W133 A134 F404 I466	Q126-I130 HydrophobicContact CG-CD1 4.3Å; Q126-I130 WeakPolarHBondContact O-CG1 3.35Å; Q126-I130 PolarHBondContact O-N 3.45Å; M127-I130 PolarHBondContact O-N 3.41Å; M127-I130 HydrophobicContact SD-CD1 3.93Å; I130-W133 PolarHBondContact O-N 2.81Å; I130-A134 WeakPolarHBondContact O-CB 3.23Å; I130-A134 PolarHBondContact O-N 3.18Å; I130-F404 HydrophobicContact CG2-CE1 4.4Å; I130-F404 HydrophobicContact CG2-CZ 4.11Å; I130-I466 HydrophobicContact CD1-CD1 4.34Å; I130-I466 HydrophobicContact CD1-CG1 3.62Å; I130-I466 HydrophobicContact CG1-CG1 4.03Å
131	R	92.8	Very high	91.5	Very high	9 Å²	9	24.9 Å²	24.9	3%	0.034	13%	0.128	C	C	.	.	H	α-helix	trans	-60.7	-47.7	173.2	166	61.1	177.3	57.6	-25.5	112.1	H115 I119 M127 A128 F129 W133 A134 D135 F404	H115-R131 PolarHBondContact CD2-NH2 3.3Å; I119-R131 HydrophobicContact CD1-CB 3.84Å; I119-R131 HydrophobicContact CD1-CG 3.82Å; M127-R131 PolarHBondContact O-N 3.49Å; M127-R131 VanDerWaalsContact O-N 3.09Å; A128-R131 WeakPolarHBondContact O-CB 3.46Å; A128-R131 PolarHBondContact O-N 2.89Å; F129-R131 PolarHBondContact O-N 2.9Å; R131-W133 VanDerWaalsContact C-N 3.34Å; R131-A134 PolarHBondContact O-N 3.26Å; R131-D135 IonicContact CZ-OD1 2.88Å; R131-D135 VanDerWaalsContact CZ-OD1 3.26Å; R131-D135 IonicContact CZ-OD2 2.76Å; R131-D135 IonicContact NE-OD1 2.67Å; R131-D135 IonicContact NH1-OD1 3.26Å; R131-D135 IonicContact NH1-OD2 3.11Å; R131-D135 PolarHBondContact NH1-OD2 3.19Å; R131-D135 IonicContact NH2-OD1 3.93Å; R131-D135 PolarHBondContact NH2-OD1 2.69Å; R131-D135 IonicContact NH2-OD2 3.62Å; R131-D135 PolarHBondContact NH2-OD2 3.33Å; R131-D135 PolarHBondContact O-N 3.2Å; R131-F404 HydrophobicContact CB-CD1 3.86Å; R131-F404 HydrophobicContact CB-CE1 3.76Å; R131-F404 HydrophobicContact CB-CZ 4.36Å; R131-F404 HydrophobicContact CG-CD1 4.22Å; R131-F404 HydrophobicContact CG-CG 4.47Å
132	L	91.3	Very high	91.4	Very high	2 Å²	2	21.8 Å²	21.8	1%	0.01	11%	0.113	C	C	.	.	H	α-helix	trans	-60.3	-43.8	178.1	169.1	66.5	0	0	0	111.6	Y116 A128 F129 D135 L136 M346 A350 Q355 L356	Y116-L132 HydrophobicContact CD2-CB 3.99Å; Y116-L132 HydrophobicContact CE2-CB 4.13Å; Y116-L132 HydrophobicContact CE2-CD2 4.09Å; A128-L132 WeakPolarHBondContact O-CB 3.37Å; A128-L132 PolarHBondContact O-N 3.01Å; F129-L132 HydrophobicContact CD2-CD2 4.19Å; F129-L132 CarbonylContact O-C 3.55Å; F129-L132 WeakPolarHBondContact O-CB 3.39Å; F129-L132 PolarHBondContact O-N 3.27Å; F129-L132 VanDerWaalsContact O-N 3.08Å; L132-D135 WeakPolarHBondContact O-CB 3.47Å; L132-D135 PolarHBondContact O-N 3.4Å; L132-L136 PolarHBondContact O-N 3.1Å; L132-M346 HydrophobicContact CB-CE 4.27Å; L132-M346 HydrophobicContact CD1-CE 3.33Å; L132-M346 HydrophobicContact CD1-CG 4.34Å; L132-M346 HydrophobicContact CG-CE 4.37Å; L132-A350 HydrophobicContact CD1-CB 3.68Å; L132-A350 HydrophobicContact CD2-CB 3.53Å; L132-A350 HydrophobicContact CG-CB 4.26Å; L132-Q355 HydrophobicContact CD2-CB 4.09Å; L132-L356 HydrophobicContact CD1-CD1 4.17Å; L132-L356 HydrophobicContact CD2-CD1 4.33Å; L132-L356 HydrophobicContact CD2-CD2 4.47Å; L132-L356 HydrophobicContact CD2-CG 4.05Å
133	W	92	Very high	91	Very high	46 Å²	46	22.6 Å²	22.6	17%	0.174	12%	0.12	C	C	.	.	H	α-helix	trans	-63.5	-44.7	177.8	-169.7	-100.1	0	0	0	112.1	F129 I130 R131 D135 L136 I137 T464 G465 A468	F129-W133 HydrophobicContact CD1-CB 4.45Å; F129-W133 HydrophobicContact CE1-CB 4.23Å; F129-W133 HydrophobicContact CE1-CD2 4.24Å; F129-W133 AromaticContact CE1-CE3 3.93Å; F129-W133 HydrophobicContact CE1-CE3 3.93Å; F129-W133 HydrophobicContact CE1-CG 4.42Å; F129-W133 HydrophobicContact CZ-CD2 4.39Å; F129-W133 AromaticContact CZ-CE3 3.63Å; F129-W133 HydrophobicContact CZ-CE3 3.63Å; F129-W133 HydrophobicContact CZ-CZ3 4.13Å; F129-W133 VanDerWaalsContact O-CB 3.29Å; F129-W133 WeakPolarHBondContact O-CB 3.29Å; F129-W133 PolarHBondContact O-N 2.9Å; I130-W133 PolarHBondContact O-N 2.81Å; R131-W133 VanDerWaalsContact C-N 3.34Å; W133-D135 VanDerWaalsContact C-N 3.32Å; W133-D135 PolarHBondContact O-N 3.42Å; W133-L136 HydrophobicContact CE3-CD2 4.42Å; W133-L136 HydrophobicContact CZ3-CD2 4.46Å; W133-L136 WeakPolarHBondContact O-CB 3.45Å; W133-L136 PolarHBondContact O-N 3.45Å; W133-I137 HydrophobicContact CD2-CD1 3.84Å; W133-I137 HydrophobicContact CE3-CD1 4.47Å; W133-I137 HydrophobicContact CG-CD1 4.33Å; W133-I137 HydrophobicContact CH2-CD1 4.05Å; W133-I137 HydrophobicContact CZ2-CD1 3.36Å; W133-I137 PolarHBondContact O-N 3.16Å; W133-T464 PolarHBondContact NE1-OG1 3.47Å; W133-G465 VanDerWaalsContact CD1-N 3.26Å; W133-A468 HydrophobicContact CD2-CB 4.25Å; W133-A468 HydrophobicContact CE3-CB 4.24Å; W133-A468 HydrophobicContact CH2-CB 3.8Å; W133-A468 HydrophobicContact CZ2-CB 3.77Å; W133-A468 HydrophobicContact CZ3-CB 4.03Å
134	A	92.4	Very high	90.6	Very high	1 Å²	1	19.6 Å²	19.6	1%	0.008	11%	0.107	C	C	.	.	H	α-helix	trans	-63.2	-37.8	174.7	0	0	0	0	0	112.4	I130 R131 A138 I139 F404	I130-A134 WeakPolarHBondContact O-CB 3.23Å; I130-A134 PolarHBondContact O-N 3.18Å; R131-A134 PolarHBondContact O-N 3.26Å; A134-A138 WeakPolarHBondContact O-CA 3.43Å; A134-A138 WeakPolarHBondContact O-CB 3.31Å; A134-A138 PolarHBondContact O-N 2.95Å; A134-I139 HydrophobicContact CB-CD1 4.34Å; A134-I139 PolarHBondContact O-N 3.42Å; A134-F404 HydrophobicContact CB-CD2 4.36Å; A134-F404 HydrophobicContact CB-CE2 3.39Å; A134-F404 HydrophobicContact CB-CZ 3.85Å
135	D	89.2	Confident	90.4	Very high	1 Å²	1	18.7 Å²	18.7	1%	0.005	10%	0.098	C	C	.	.	I	π-helix	trans	-63.3	-44	173.4	-102.6	19.4	0	0	0	111.6	R131 L132 W133 I139 R140 M346	R131-D135 IonicContact CZ-OD1 2.88Å; R131-D135 VanDerWaalsContact CZ-OD1 3.26Å; R131-D135 IonicContact CZ-OD2 2.76Å; R131-D135 IonicContact NE-OD1 2.67Å; R131-D135 IonicContact NH1-OD1 3.26Å; R131-D135 IonicContact NH1-OD2 3.11Å; R131-D135 PolarHBondContact NH1-OD2 3.19Å; R131-D135 IonicContact NH2-OD1 3.93Å; R131-D135 PolarHBondContact NH2-OD1 2.69Å; R131-D135 IonicContact NH2-OD2 3.62Å; R131-D135 PolarHBondContact NH2-OD2 3.33Å; R131-D135 PolarHBondContact O-N 3.2Å; L132-D135 WeakPolarHBondContact O-CB 3.47Å; L132-D135 PolarHBondContact O-N 3.4Å; W133-D135 VanDerWaalsContact C-N 3.32Å; W133-D135 PolarHBondContact O-N 3.42Å; D135-I139 WeakPolarHBondContact OD1-CD1 3.4Å; D135-R140 HydrophobicContact CB-CG 4.14Å; D135-R140 WeakPolarHBondContact O-CB 3.29Å; D135-R140 WeakPolarHBondContact O-CG 3.47Å; D135-R140 PolarHBondContact O-N 3.31Å; D135-R140 IonicContact OD2-NE 2.74Å; D135-R140 IonicContact OD2-NH2 3.86Å; D135-M346 HydrophobicContact CB-CE 3.5Å; D135-M346 VanDerWaalsContact CB-CE 3.5Å; D135-M346 HydrophobicContact CB-SD 4.28Å; D135-M346 VanDerWaalsContact OD2-CE 3.28Å; D135-M346 WeakPolarHBondContact OD2-CE 3.22Å
136	L	87.9	Confident	90.2	Very high	22 Å²	22	15.7 Å²	15.7	12%	0.115	8%	0.078	C	C	.	.	I	π-helix	trans	-61.8	-51.4	-177.9	-175.1	83.4	0	0	0	112.4	L132 W133 P141 F347 I376	L132-L136 PolarHBondContact O-N 3.1Å; W133-L136 HydrophobicContact CE3-CD2 4.42Å; W133-L136 HydrophobicContact CZ3-CD2 4.46Å; W133-L136 WeakPolarHBondContact O-CB 3.45Å; W133-L136 PolarHBondContact O-N 3.45Å; L136-P141 WeakPolarHBondContact O-CD 3.44Å; L136-P141 VanDerWaalsContact O-CG 3.25Å; L136-P141 WeakPolarHBondContact O-CG 3.28Å; L136-F347 HydrophobicContact CD1-CD1 4.5Å; L136-F347 HydrophobicContact CD1-CE1 3.43Å; L136-F347 VanDerWaalsContact CD1-CE1 3.43Å; L136-F347 HydrophobicContact CD1-CE2 4.01Å; L136-F347 HydrophobicContact CD1-CZ 3.15Å; L136-I376 HydrophobicContact CD1-CG2 4.42Å
137	I	89	Confident	89.8	Confident	30 Å²	30	14.1 Å²	14.1	15%	0.154	7%	0.071	C	C	.	.	I	π-helix	trans	-96.5	-30.2	-166.6	-50.7	-172.4	0	0	0	111.9	W133 Q384 M461	W133-I137 HydrophobicContact CD2-CD1 3.84Å; W133-I137 HydrophobicContact CE3-CD1 4.47Å; W133-I137 HydrophobicContact CG-CD1 4.33Å; W133-I137 HydrophobicContact CH2-CD1 4.05Å; W133-I137 HydrophobicContact CZ2-CD1 3.36Å; W133-I137 PolarHBondContact O-N 3.16Å; I137-Q384 PolarHBondContact O-NE2 3.26Å; I137-M461 HydrophobicContact CB-CE 4.39Å; I137-M461 HydrophobicContact CG2-CE 3.41Å; I137-M461 VanDerWaalsContact CG2-CE 3.41Å
138	A	89.4	Confident	89.6	Confident	0 Å²	0	11 Å²	11	0%	0	6%	0.056	C	C	.	.	I	π-helix	trans	-114.9	-67.7	-171.5	0	0	0	0	0	112.5	A134 R140 A142 F396 L400	A134-A138 WeakPolarHBondContact O-CA 3.43Å; A134-A138 WeakPolarHBondContact O-CB 3.31Å; A134-A138 PolarHBondContact O-N 2.95Å; A138-R140 PolarHBondContact O-N 3.31Å; A138-A142 WeakPolarHBondContact O-CB 3.34Å; A138-A142 PolarHBondContact O-N 3.08Å; A138-A142 VanDerWaalsContact O-N 3.16Å; A138-F396 HydrophobicContact CB-CE1 3.65Å; A138-F396 HydrophobicContact CB-CZ 3.57Å; A138-L400 HydrophobicContact CB-CD1 3.41Å; A138-L400 VanDerWaalsContact CB-CD1 3.41Å
139	I	89.6	Confident	89.3	Confident	13 Å²	13	11.2 Å²	11.2	7%	0.067	6%	0.057	C	C	.	.	I	π-helix	trans	-66.1	-48	-164.4	-59.3	163	0	0	0	111.9	A134 D135 A143 L400 F404	A134-I139 HydrophobicContact CB-CD1 4.34Å; A134-I139 PolarHBondContact O-N 3.42Å; D135-I139 WeakPolarHBondContact OD1-CD1 3.4Å; I139-A143 WeakPolarHBondContact O-CB 3.48Å; I139-A143 PolarHBondContact O-N 3.42Å; I139-L400 HydrophobicContact CD1-CB 3.84Å; I139-L400 HydrophobicContact CG1-CB 3.66Å; I139-L400 HydrophobicContact CG1-CD1 4.1Å; I139-F404 HydrophobicContact CD1-CD2 4.09Å
140	R	87.2	Confident	88.9	Confident	20 Å²	20	11.3 Å²	11.3	8%	0.075	6%	0.059	C	C	.	.	H	α-helix	trans	-73.9	-46.7	-173	-61.2	-84	-176.4	-164.4	1.9	112.8	D135 A138 A142 A143 L144 Y256 L343 L377	D135-R140 HydrophobicContact CB-CG 4.14Å; D135-R140 WeakPolarHBondContact O-CB 3.29Å; D135-R140 WeakPolarHBondContact O-CG 3.47Å; D135-R140 PolarHBondContact O-N 3.31Å; D135-R140 IonicContact OD2-NE 2.74Å; D135-R140 IonicContact OD2-NH2 3.86Å; A138-R140 PolarHBondContact O-N 3.31Å; R140-A142 PolarHBondContact O-N 3.44Å; R140-A143 PolarHBondContact O-N 3.48Å; R140-L144 PolarHBondContact O-N 2.71Å; R140-Y256 PolarHBondContact NH1-OH 3.35Å; R140-L343 HydrophobicContact CB-CD1 3.55Å; R140-L343 HydrophobicContact CG-CD1 3.59Å; R140-L377 HydrophobicContact CB-CD1 4.38Å
141	P	89.4	Confident	88.6	Confident	0 Å²	0	11.9 Å²	11.9	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-59.2	-38	173.6	-20	30.7	0	0	0	111.8	L136 L144 A145 L377 M380 Q384	L136-P141 WeakPolarHBondContact O-CD 3.44Å; L136-P141 VanDerWaalsContact O-CG 3.25Å; L136-P141 WeakPolarHBondContact O-CG 3.28Å; P141-L144 PolarHBondContact O-N 3.28Å; P141-A145 VanDerWaalsContact O-CB 3.31Å; P141-A145 WeakPolarHBondContact O-CB 3.38Å; P141-A145 PolarHBondContact O-N 3.48Å; P141-L377 HydrophobicContact CG-CD1 3.94Å; P141-M380 HydrophobicContact CB-CB 3.99Å; P141-M380 HydrophobicContact CG-CB 3.81Å; P141-Q384 VanDerWaalsContact C-OE1 3.3Å
142	A	89.8	Confident	88.4	Confident	0 Å²	0	11.4 Å²	11.4	0%	0	6%	0.059	C	C	.	.	H	α-helix	trans	-67.3	-45.2	-179.4	0	0	0	0	0	111.5	A138 R140 L144 A145 V146 L393 F396 M397	A138-A142 WeakPolarHBondContact O-CB 3.34Å; A138-A142 PolarHBondContact O-N 3.08Å; A138-A142 VanDerWaalsContact O-N 3.16Å; R140-A142 PolarHBondContact O-N 3.44Å; A142-L144 VanDerWaalsContact C-N 3.34Å; A142-L144 PolarHBondContact O-N 3.48Å; A142-A145 PolarHBondContact O-N 3.23Å; A142-V146 WeakPolarHBondContact O-CG2 3.48Å; A142-V146 PolarHBondContact O-N 2.99Å; A142-L393 HydrophobicContact CB-CD2 4.49Å; A142-F396 HydrophobicContact CB-CD1 3.92Å; A142-F396 HydrophobicContact CB-CE1 4.2Å; A142-M397 HydrophobicContact CB-CB 3.7Å; A142-M397 HydrophobicContact CB-SD 4.44Å
143	A	86.4	Confident	88.2	Confident	29 Å²	29	14.3 Å²	14.3	24%	0.24	7%	0.07	C	C	.	.	H	α-helix	trans	-60.4	-43.5	177	0	0	0	0	0	111.9	I139 R140 I147 M397	I139-A143 WeakPolarHBondContact O-CB 3.48Å; I139-A143 PolarHBondContact O-N 3.42Å; R140-A143 PolarHBondContact O-N 3.48Å; A143-I147 WeakPolarHBondContact O-CD1 3.35Å; A143-I147 VanDerWaalsContact O-CG1 3.28Å; A143-I147 WeakPolarHBondContact O-CG1 3.32Å; A143-I147 PolarHBondContact O-N 3.18Å; A143-I147 VanDerWaalsContact O-N 3.14Å; A143-M397 VanDerWaalsContact CA-SD 3.51Å; A143-M397 HydrophobicContact CB-SD 3.87Å
144	L	86.4	Confident	87.8	Confident	7 Å²	7	12.6 Å²	12.6	4%	0.037	6%	0.063	C	C	.	.	H	α-helix	trans	-65.8	-42.3	175.6	-72.6	173.5	0	0	0	111.6	R140 P141 A142 V146 I147 S148 L377 T381	R140-L144 PolarHBondContact O-N 2.71Å; P141-L144 PolarHBondContact O-N 3.28Å; A142-L144 VanDerWaalsContact C-N 3.34Å; A142-L144 PolarHBondContact O-N 3.48Å; L144-V146 PolarHBondContact O-N 2.93Å; L144-I147 PolarHBondContact O-N 3.37Å; L144-S148 VanDerWaalsContact O-CB 3.28Å; L144-S148 WeakPolarHBondContact O-CB 3.23Å; L144-S148 PolarHBondContact O-N 3.38Å; L144-S148 PolarHBondContact O-OG 2.86Å; L144-L377 HydrophobicContact CD1-CD1 4.48Å; L144-L377 HydrophobicContact CD1-CD2 3.3Å; L144-L377 HydrophobicContact CD1-CG 4.04Å; L144-T381 HydrophobicContact CB-CG2 3.74Å
145	A	89.7	Confident	87.5	Confident	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-60.8	-44.5	177.2	0	0	0	0	0	111.9	P141 A142 S148 L149 T381 Q384 L385 L393	P141-A145 VanDerWaalsContact O-CB 3.31Å; P141-A145 WeakPolarHBondContact O-CB 3.38Å; P141-A145 PolarHBondContact O-N 3.48Å; A142-A145 PolarHBondContact O-N 3.23Å; A145-S148 PolarHBondContact O-N 3.45Å; A145-L149 WeakPolarHBondContact O-CB 3.47Å; A145-L149 VanDerWaalsContact O-CG 3.29Å; A145-L149 WeakPolarHBondContact O-CG 3.47Å; A145-L149 PolarHBondContact O-N 3.09Å; A145-T381 HydrophobicContact CB-CG2 4.17Å; A145-Q384 HydrophobicContact CB-CB 4.42Å; A145-L385 HydrophobicContact CB-CB 4.32Å; A145-L393 HydrophobicContact CB-CD1 4.01Å
146	V	86.4	Confident	87.5	Confident	2 Å²	2	17.4 Å²	17.4	1%	0.012	9%	0.088	C	C	.	.	H	α-helix	trans	-59.9	-50.1	176.9	167	0	0	0	0	111.6	A142 L144 S148 L149 A150 I390 L393 L394 M397	A142-V146 WeakPolarHBondContact O-CG2 3.48Å; A142-V146 PolarHBondContact O-N 2.99Å; L144-V146 PolarHBondContact O-N 2.93Å; V146-S148 VanDerWaalsContact C-N 3.28Å; V146-S148 PolarHBondContact O-N 3.28Å; V146-L149 PolarHBondContact O-N 2.95Å; V146-A150 PolarHBondContact O-N 3.03Å; V146-I390 HydrophobicContact CG1-CG2 4.38Å; V146-L393 HydrophobicContact CG2-CB 3.55Å; V146-L393 HydrophobicContact CG2-CD1 4.45Å; V146-L394 HydrophobicContact CG1-CD2 3.68Å; V146-L394 HydrophobicContact CG1-CG 3.97Å; V146-L394 HydrophobicContact CG2-CD2 4.22Å; V146-L394 HydrophobicContact CG2-CG 4.09Å; V146-M397 HydrophobicContact CG2-SD 4.35Å
147	I	84.2	Confident	87.3	Confident	34 Å²	34	17.7 Å²	17.7	17%	0.174	9%	0.089	C	C	.	.	H	α-helix	trans	-63.5	-39.1	179.9	-63.6	166.3	0	0	0	110.3	A143 L144 A150 F151 C332 M336	A143-I147 WeakPolarHBondContact O-CD1 3.35Å; A143-I147 VanDerWaalsContact O-CG1 3.28Å; A143-I147 WeakPolarHBondContact O-CG1 3.32Å; A143-I147 PolarHBondContact O-N 3.18Å; A143-I147 VanDerWaalsContact O-N 3.14Å; L144-I147 PolarHBondContact O-N 3.37Å; I147-A150 WeakPolarHBondContact O-CB 3.49Å; I147-A150 PolarHBondContact O-N 3.15Å; I147-F151 PolarHBondContact O-N 3.1Å; I147-C332 HydrophobicContact CG2-CB 4.02Å; I147-C332 WeakPolarHBondContact CG2-O 3.44Å; I147-M336 HydrophobicContact CB-CG 4.24Å; I147-M336 HydrophobicContact CG2-CG 3.61Å
148	S	88.2	Confident	87	Confident	0 Å²	0	18 Å²	18	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-66.1	-43	177.9	-50.5	0	0	0	0	111.2	L144 A145 V146 A150 F151 G152 T174 M336	L144-S148 VanDerWaalsContact O-CB 3.28Å; L144-S148 WeakPolarHBondContact O-CB 3.23Å; L144-S148 PolarHBondContact O-N 3.38Å; L144-S148 PolarHBondContact O-OG 2.86Å; A145-S148 PolarHBondContact O-N 3.45Å; V146-S148 VanDerWaalsContact C-N 3.28Å; V146-S148 PolarHBondContact O-N 3.28Å; S148-A150 VanDerWaalsContact C-N 3.28Å; S148-A150 PolarHBondContact O-N 2.82Å; S148-F151 WeakPolarHBondContact O-CA 3.46Å; S148-F151 VanDerWaalsContact O-CB 3.27Å; S148-F151 WeakPolarHBondContact O-CB 3.37Å; S148-F151 PolarHBondContact O-N 3.35Å; S148-F151 VanDerWaalsContact O-N 3.1Å; S148-G152 PolarHBondContact O-N 3.24Å; S148-T174 WeakPolarHBondContact O-CG2 3.36Å; S148-T174 PolarHBondContact O-OG1 3.45Å; S148-M336 WeakPolarHBondContact OG-CE 3.48Å; S148-M336 PolarHBondContact OG-SD 2.97Å
149	L	87.8	Confident	86.8	Confident	5 Å²	5	24.5 Å²	24.5	3%	0.026	13%	0.127	C	C	.	.	H	α-helix	trans	-63	-37.4	177.2	-76.1	168.6	0	0	0	111.6	A145 V146 G152 R153 V170 K171 T174 L385 I390 L393	A145-L149 WeakPolarHBondContact O-CB 3.47Å; A145-L149 VanDerWaalsContact O-CG 3.29Å; A145-L149 WeakPolarHBondContact O-CG 3.47Å; A145-L149 PolarHBondContact O-N 3.09Å; V146-L149 PolarHBondContact O-N 2.95Å; L149-G152 PolarHBondContact O-N 3.46Å; L149-R153 WeakPolarHBondContact O-CB 3.27Å; L149-R153 PolarHBondContact O-N 2.87Å; L149-V170 HydrophobicContact CD2-CG1 4.35Å; L149-K171 HydrophobicContact CD2-CG 4.14Å; L149-T174 HydrophobicContact CD2-CG2 4.48Å; L149-L385 HydrophobicContact CD2-CG 4.29Å; L149-I390 HydrophobicContact CB-CD1 3.91Å; L149-I390 HydrophobicContact CB-CG1 3.67Å; L149-I390 HydrophobicContact CD1-CG1 3.8Å; L149-I390 HydrophobicContact CG-CG1 4.33Å; L149-L393 HydrophobicContact CD1-CD1 3.96Å
150	A	84.1	Confident	86.5	Confident	5 Å²	5	27.2 Å²	27.2	4%	0.041	14%	0.138	C	C	.	.	H	α-helix	trans	-61.3	-48.1	170.7	0	0	0	0	0	110.9	V146 I147 S148 G152 R153 Y154	V146-A150 PolarHBondContact O-N 3.03Å; I147-A150 WeakPolarHBondContact O-CB 3.49Å; I147-A150 PolarHBondContact O-N 3.15Å; S148-A150 VanDerWaalsContact C-N 3.28Å; S148-A150 PolarHBondContact O-N 2.82Å; A150-G152 PolarHBondContact O-N 2.94Å; A150-R153 PolarHBondContact O-N 3.34Å; A150-Y154 WeakPolarHBondContact O-CD2 3.47Å; A150-Y154 PolarHBondContact O-N 3.39Å
151	F	87.3	Confident	86	Confident	23 Å²	23	29 Å²	29	10%	0.101	15%	0.148	C	C	.	.	H	α-helix	trans	-52.7	-51.4	174.2	168	-94.7	0	0	0	112.4	I147 S148 R153 Y154 I155 A329 C332	I147-F151 PolarHBondContact O-N 3.1Å; S148-F151 WeakPolarHBondContact O-CA 3.46Å; S148-F151 VanDerWaalsContact O-CB 3.27Å; S148-F151 WeakPolarHBondContact O-CB 3.37Å; S148-F151 PolarHBondContact O-N 3.35Å; S148-F151 VanDerWaalsContact O-N 3.1Å; F151-R153 VanDerWaalsContact C-N 3.26Å; F151-R153 PolarHBondContact O-N 3.23Å; F151-Y154 PolarHBondContact O-N 2.96Å; F151-I155 HydrophobicContact CE1-CD1 4.32Å; F151-I155 HydrophobicContact CE2-CD1 4.24Å; F151-I155 HydrophobicContact CZ-CD1 3.7Å; F151-I155 PolarHBondContact O-N 3.33Å; F151-A329 HydrophobicContact CD2-CB 3.87Å; F151-A329 VanDerWaalsContact CD2-O 3.29Å; F151-A329 WeakPolarHBondContact CD2-O 3.38Å; F151-A329 HydrophobicContact CE2-CB 4.01Å; F151-C332 HydrophobicContact CB-CB 3.71Å; F151-C332 HydrophobicContact CD2-CB 4.46Å
152	G	88.9	Confident	85.2	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-64.9	-29.2	-179	0	0	0	0	0	113.5	S148 L149 A150 I155 L156 T174	S148-G152 PolarHBondContact O-N 3.24Å; L149-G152 PolarHBondContact O-N 3.46Å; A150-G152 PolarHBondContact O-N 2.94Å; G152-I155 WeakPolarHBondContact O-CG2 3.37Å; G152-L156 VanDerWaalsContact O-CG 3.26Å; G152-L156 WeakPolarHBondContact O-CG 3.25Å; G152-T174 WeakPolarHBondContact CA-OG1 3.5Å
153	R	86.3	Confident	85	Confident	62 Å²	62	39.7 Å²	39.7	23%	0.234	22%	0.219	C	C	.	.	H	α-helix	trans	-71.3	-53.4	173.2	-171.8	178.1	-171.8	131.3	11.6	111.1	L149 A150 F151 I155 L156 E157 I165 V170 E306	L149-R153 WeakPolarHBondContact O-CB 3.27Å; L149-R153 PolarHBondContact O-N 2.87Å; A150-R153 PolarHBondContact O-N 3.34Å; F151-R153 VanDerWaalsContact C-N 3.26Å; F151-R153 PolarHBondContact O-N 3.23Å; R153-I155 VanDerWaalsContact C-N 3.3Å; R153-I155 PolarHBondContact O-N 3.14Å; R153-L156 PolarHBondContact O-N 2.84Å; R153-L156 VanDerWaalsContact O-N 3.11Å; R153-E157 PolarHBondContact O-N 3.48Å; R153-I165 HydrophobicContact CG-CD1 4.18Å; R153-V170 HydrophobicContact CB-CG1 4.24Å; R153-E306 IonicContact CZ-OE2 3.33Å; R153-E306 IonicContact NH2-OE1 3.58Å; R153-E306 PolarHBondContact NH2-OE1 2.69Å; R153-E306 IonicContact NH2-OE2 3.85Å; R153-E306 PolarHBondContact NH2-OE2 3.4Å
154	Y	83.9	Confident	84.7	Confident	10 Å²	10	42.9 Å²	42.9	4%	0.039	24%	0.239	C	C	.	.	H	α-helix	trans	-64.5	-31	-176.7	-79.7	-74.5	0	0	0	113.2	A150 F151 L156 P158 A307 V310 P325 V328	A150-Y154 WeakPolarHBondContact O-CD2 3.47Å; A150-Y154 PolarHBondContact O-N 3.39Å; F151-Y154 PolarHBondContact O-N 2.96Å; Y154-L156 VanDerWaalsContact C-N 3.35Å; Y154-P158 WeakPolarHBondContact O-CD 3.32Å; Y154-A307 HydrophobicContact CE1-CB 4Å; Y154-V310 HydrophobicContact CD1-CG2 4.11Å; Y154-V310 HydrophobicContact CE1-CG2 3.96Å; Y154-P325 HydrophobicContact CD1-CB 4.17Å; Y154-P325 WeakPolarHBondContact O-CB 3.41Å; Y154-V328 HydrophobicContact CD1-CB 3.99Å; Y154-V328 HydrophobicContact CD1-CG1 3.85Å; Y154-V328 HydrophobicContact CD2-CB 4.4Å; Y154-V328 HydrophobicContact CD2-CG1 3.49Å; Y154-V328 VanDerWaalsContact CD2-CG1 3.49Å; Y154-V328 HydrophobicContact CE1-CB 4.26Å; Y154-V328 HydrophobicContact CE1-CG1 3.88Å; Y154-V328 HydrophobicContact CE1-CG2 4.48Å; Y154-V328 HydrophobicContact CE2-CG1 3.57Å; Y154-V328 HydrophobicContact CG-CB 4.07Å; Y154-V328 HydrophobicContact CG-CG1 3.66Å
155	I	87.4	Confident	84.7	Confident	81 Å²	81	43.6 Å²	43.6	42%	0.415	24%	0.243	S	C	.	.	H	α-helix	trans	-73.1	-28.5	176	-157.5	166.8	0	0	0	112.8	F151 G152 R153 A329	F151-I155 HydrophobicContact CE1-CD1 4.32Å; F151-I155 HydrophobicContact CE2-CD1 4.24Å; F151-I155 HydrophobicContact CZ-CD1 3.7Å; F151-I155 PolarHBondContact O-N 3.33Å; G152-I155 WeakPolarHBondContact O-CG2 3.37Å; R153-I155 VanDerWaalsContact C-N 3.3Å; R153-I155 PolarHBondContact O-N 3.14Å; I155-A329 HydrophobicContact CB-CB 4.46Å
156	L	88.4	Confident	84.8	Confident	22 Å²	22	46.6 Å²	46.6	12%	0.115	26%	0.262	C	S	.	.	H	α-helix	trans	-88	-24.7	179.3	-69.7	-179.3	0	0	0	112.6	G152 R153 Y154 P158 L159 F160 I165 A169 V170 A173	G152-L156 VanDerWaalsContact O-CG 3.26Å; G152-L156 WeakPolarHBondContact O-CG 3.25Å; R153-L156 PolarHBondContact O-N 2.84Å; R153-L156 VanDerWaalsContact O-N 3.11Å; Y154-L156 VanDerWaalsContact C-N 3.35Å; L156-P158 VanDerWaalsContact C-CD 3.49Å; L156-L159 HydrophobicContact CD2-CD1 4.2Å; L156-L159 WeakPolarHBondContact O-CB 3.44Å; L156-L159 PolarHBondContact O-N 2.87Å; L156-F160 HydrophobicContact CB-CD2 4.22Å; L156-F160 HydrophobicContact CB-CE2 4.5Å; L156-F160 HydrophobicContact CD2-CE2 4.26Å; L156-F160 WeakPolarHBondContact O-CD2 3.35Å; L156-F160 PolarHBondContact O-N 3.34Å; L156-I165 HydrophobicContact CB-CD1 3.99Å; L156-I165 HydrophobicContact CB-CG2 4.23Å; L156-I165 HydrophobicContact CD1-CG2 3.9Å; L156-A169 HydrophobicContact CD1-CB 4.19Å; L156-V170 HydrophobicContact CD1-CG2 4.32Å; L156-A173 HydrophobicContact CD1-CB 3.76Å; L156-A173 HydrophobicContact CD2-CB 4.23Å; L156-A173 HydrophobicContact CG-CB 4.05Å
157	E	83.4	Confident	84.8	Confident	28 Å²	28	51.4 Å²	51.4	13%	0.131	29%	0.293	C	S	.	.	H	α-helix	trans	-47.3	-50.8	-178	-155.7	79.4	-168.3	0	0	113.1	R153 L159 F160 M161 I165 V310	R153-E157 PolarHBondContact O-N 3.48Å; E157-L159 PolarHBondContact O-N 3.25Å; E157-L159 VanDerWaalsContact O-N 3.14Å; E157-F160 PolarHBondContact O-N 3.44Å; E157-M161 HydrophobicContact CG-CG 4.37Å; E157-M161 WeakPolarHBondContact O-CG 3.44Å; E157-M161 PolarHBondContact O-N 2.96Å; E157-I165 VanDerWaalsContact OE2-CD1 3.29Å; E157-I165 WeakPolarHBondContact OE2-CD1 3.29Å; E157-V310 HydrophobicContact CG-CG1 4.36Å; E157-V310 HydrophobicContact CG-CG2 4.31Å
158	P	82.3	Confident	85	Confident	37 Å²	37	55.1 Å²	55.1	24%	0.24	31%	0.313	C	S	.	.	H	α-helix	trans	-63.9	-24.3	-178.9	-21.8	35.6	0	0	0	114.6	Y154 L156 V322 P325	Y154-P158 WeakPolarHBondContact O-CD 3.32Å; L156-P158 VanDerWaalsContact C-CD 3.49Å; P158-V322 HydrophobicContact CB-CG1 3.96Å; P158-V322 HydrophobicContact CG-CG1 4.24Å; P158-P325 HydrophobicContact CG-CB 4.12Å; P158-P325 HydrophobicContact CG-CG 3.66Å
159	L	85.1	Confident	85.2	Confident	136 Å²	136	56.5 Å²	56.5	71%	0.712	33%	0.325	S	S	*	.	H	α-helix	trans	-83.6	-24.4	-178	-61.1	175.1	0	0	0	112.3	L156 E157	L156-L159 HydrophobicContact CD2-CD1 4.2Å; L156-L159 WeakPolarHBondContact O-CB 3.44Å; L156-L159 PolarHBondContact O-N 2.87Å; E157-L159 PolarHBondContact O-N 3.25Å; E157-L159 VanDerWaalsContact O-N 3.14Å
160	F	84	Confident	85.2	Confident	71 Å²	71	57.1 Å²	57.1	31%	0.311	33%	0.328	S	S	.	.	H	α-helix	trans	-109.5	-11.4	-174.9	-76.1	-92.4	0	0	0	113.3	L156 E157 C163 I165	L156-F160 HydrophobicContact CB-CD2 4.22Å; L156-F160 HydrophobicContact CB-CE2 4.5Å; L156-F160 HydrophobicContact CD2-CE2 4.26Å; L156-F160 WeakPolarHBondContact O-CD2 3.35Å; L156-F160 PolarHBondContact O-N 3.34Å; E157-F160 PolarHBondContact O-N 3.44Å; F160-C163 VanDerWaalsContact O-CA 3.32Å; F160-C163 WeakPolarHBondContact O-CA 3.3Å; F160-C163 VanDerWaalsContact O-CB 3.29Å; F160-C163 WeakPolarHBondContact O-CB 3.27Å; F160-C163 PolarHBondContact O-N 3.41Å; F160-C163 VanDerWaalsContact O-O 3.11Å; F160-I165 HydrophobicContact CB-CG1 3.73Å; F160-I165 HydrophobicContact CD2-CG1 4.28Å; F160-I165 HydrophobicContact CD2-CG2 4.34Å; F160-I165 HydrophobicContact CG-CG1 4.04Å; F160-I165 HydrophobicContact CG-CG2 4.49Å
161	M	75.7	Confident	85.6	Confident	57 Å²	57	59.1 Å²	59.1	28%	0.281	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	-54.5	128.9	175.6	-84.3	-166.9	-73.3	0	0	111.8	E157 V310	E157-M161 HydrophobicContact CG-CG 4.37Å; E157-M161 WeakPolarHBondContact O-CG 3.44Å; E157-M161 PolarHBondContact O-N 2.96Å; M161-V310 HydrophobicContact CE-CG1 4.24Å; M161-V310 HydrophobicContact SD-CG1 3.92Å
162	P	74.6	Confident	85.8	Confident	137 Å²	137	62.1 Å²	62.1	89%	0.89	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	cis	-96.2	9.4	6.9	38.1	-36.1	0	0	0	115.6
163	C	83.9	Confident	86	Confident	88 Å²	88	63.2 Å²	63.2	60%	0.595	36%	0.362	S	S	*	.	S	Bend	trans	-78.7	151.3	-178.9	-61.6	0	0	0	0	112.8	F160	F160-C163 VanDerWaalsContact O-CA 3.32Å; F160-C163 WeakPolarHBondContact O-CA 3.3Å; F160-C163 VanDerWaalsContact O-CB 3.29Å; F160-C163 WeakPolarHBondContact O-CB 3.27Å; F160-C163 PolarHBondContact O-N 3.41Å; F160-C163 VanDerWaalsContact O-O 3.11Å
164	S	82	Confident	86.2	Confident	96 Å²	96	60.2 Å²	60.2	67%	0.671	35%	0.351	S	S	*	.	P	Polyproline II helix	trans	-68.5	133.6	172.8	60	0	0	0	0	111.6
165	I	86.1	Confident	86.6	Confident	21 Å²	21	60.4 Å²	60.4	11%	0.108	35%	0.354	C	S	.	.	P	Polyproline II helix	trans	-73.6	129.8	178.7	-51.9	159.9	0	0	0	110.1	R153 L156 E157 F160 A169 V170	R153-I165 HydrophobicContact CG-CD1 4.18Å; L156-I165 HydrophobicContact CB-CD1 3.99Å; L156-I165 HydrophobicContact CB-CG2 4.23Å; L156-I165 HydrophobicContact CD1-CG2 3.9Å; E157-I165 VanDerWaalsContact OE2-CD1 3.29Å; E157-I165 WeakPolarHBondContact OE2-CD1 3.29Å; F160-I165 HydrophobicContact CB-CG1 3.73Å; F160-I165 HydrophobicContact CD2-CG1 4.28Å; F160-I165 HydrophobicContact CD2-CG2 4.34Å; F160-I165 HydrophobicContact CG-CG1 4.04Å; F160-I165 HydrophobicContact CG-CG2 4.49Å; I165-A169 HydrophobicContact CG2-CB 4.31Å; I165-V170 HydrophobicContact CB-CG2 4.16Å; I165-V170 HydrophobicContact CG2-CG2 3.55Å
166	P	90.3	Very high	86.8	Confident	63 Å²	63	62.4 Å²	62.4	41%	0.409	36%	0.364	S	S	.	.	P	Polyproline II helix	trans	-58.6	132.5	173	-24.4	34	0	0	0	111.9	L168 A169 V170	P166-L168 PolarHBondContact O-N 3.43Å; P166-L168 VanDerWaalsContact O-N 3.15Å; P166-A169 HydrophobicContact CB-CB 4.21Å; P166-A169 WeakPolarHBondContact O-CB 3.36Å; P166-A169 PolarHBondContact O-N 2.87Å; P166-V170 PolarHBondContact O-N 3.47Å
167	P	86.6	Confident	86.7	Confident	103 Å²	103	61.8 Å²	61.8	67%	0.669	36%	0.364	S	S	*	.	H	α-helix	trans	-57.8	-34.4	-177.6	-27.4	34.4	0	0	0	113.9	V170 K171	P167-V170 PolarHBondContact O-N 3.03Å; P167-K171 PolarHBondContact O-N 3.47Å
168	L	89.9	Confident	86.9	Confident	113 Å²	113	60.5 Å²	60.5	59%	0.592	36%	0.358	S	S	*	.	H	α-helix	trans	-65.9	-37.7	176.8	-174.5	64.2	0	0	0	111.9	P166 K171 L172	P166-L168 PolarHBondContact O-N 3.43Å; P166-L168 VanDerWaalsContact O-N 3.15Å; L168-K171 PolarHBondContact O-N 2.84Å; L168-L172 HydrophobicContact CD1-CD1 4.48Å; L168-L172 HydrophobicContact CD1-CG 4.39Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.39Å; L168-L172 WeakPolarHBondContact O-CB 3.02Å; L168-L172 VanDerWaalsContact O-CG 3.32Å; L168-L172 WeakPolarHBondContact O-CG 3.38Å; L168-L172 PolarHBondContact O-N 3.2Å
169	A	90.7	Very high	87.3	Confident	29 Å²	29	60.2 Å²	60.2	24%	0.24	36%	0.356	C	S	.	.	H	α-helix	trans	-63.8	-42.8	177.3	0	0	0	0	0	110.9	L156 I165 P166 L172 A173	L156-A169 HydrophobicContact CD1-CB 4.19Å; I165-A169 HydrophobicContact CG2-CB 4.31Å; P166-A169 HydrophobicContact CB-CB 4.21Å; P166-A169 WeakPolarHBondContact O-CB 3.36Å; P166-A169 PolarHBondContact O-N 2.87Å; A169-L172 PolarHBondContact O-N 3.45Å; A169-A173 VanDerWaalsContact O-CB 3.3Å; A169-A173 WeakPolarHBondContact O-CB 3.27Å; A169-A173 PolarHBondContact O-N 3.36Å
170	V	89.7	Confident	87.4	Confident	17 Å²	17	59.3 Å²	59.3	10%	0.103	35%	0.347	C	S	.	.	H	α-helix	trans	-59.3	-48.4	173.7	179.7	0	0	0	0	110.7	L149 R153 L156 I165 P166 P167 L172 A173 T174	L149-V170 HydrophobicContact CD2-CG1 4.35Å; R153-V170 HydrophobicContact CB-CG1 4.24Å; L156-V170 HydrophobicContact CD1-CG2 4.32Å; I165-V170 HydrophobicContact CB-CG2 4.16Å; I165-V170 HydrophobicContact CG2-CG2 3.55Å; P166-V170 PolarHBondContact O-N 3.47Å; P167-V170 PolarHBondContact O-N 3.03Å; V170-L172 PolarHBondContact O-N 3.17Å; V170-A173 PolarHBondContact O-N 2.93Å; V170-T174 WeakPolarHBondContact O-CB 3.37Å; V170-T174 PolarHBondContact O-N 3.39Å; V170-T174 PolarHBondContact O-OG1 2.86Å
171	K	91.3	Very high	87.2	Confident	47 Å²	47	56 Å²	56	20%	0.204	33%	0.333	C	S	.	.	H	α-helix	trans	-61.1	-43.3	179.5	-74.7	-174.1	172.5	-172.2	0	112.2	L149 P167 L168 T174 A175 L385 F386 G388	L149-K171 HydrophobicContact CD2-CG 4.14Å; P167-K171 PolarHBondContact O-N 3.47Å; L168-K171 PolarHBondContact O-N 2.84Å; K171-T174 PolarHBondContact O-N 3.45Å; K171-A175 WeakPolarHBondContact O-CB 3.47Å; K171-A175 PolarHBondContact O-N 3.38Å; K171-L385 HydrophobicContact CB-CD2 4.19Å; K171-L385 VanDerWaalsContact CE-O 3.29Å; K171-L385 WeakPolarHBondContact CE-O 3.48Å; K171-L385 HydrophobicContact CG-CD2 4.39Å; K171-F386 HydrophobicContact CB-CE1 4.28Å; K171-F386 HydrophobicContact CD-CD1 4.32Å; K171-F386 PolarHBondContact NZ-O 3.47Å; K171-G388 WeakPolarHBondContact CE-O 3.37Å; K171-G388 PolarHBondContact NZ-O 3.32Å; K171-G388 VanDerWaalsContact NZ-O 3.14Å
172	L	92.5	Very high	87.5	Confident	87 Å²	87	53.7 Å²	53.7	46%	0.455	32%	0.321	S	S	.	.	H	α-helix	trans	-68.6	-47	178.9	-69.1	174.4	0	0	0	112.5	L168 A169 V170 T174 A175 I176	L168-L172 HydrophobicContact CD1-CD1 4.48Å; L168-L172 HydrophobicContact CD1-CG 4.39Å; L168-L172 HydrophobicContact CG-CD1 4.07Å; L168-L172 HydrophobicContact CG-CG 4.39Å; L168-L172 WeakPolarHBondContact O-CB 3.02Å; L168-L172 VanDerWaalsContact O-CG 3.32Å; L168-L172 WeakPolarHBondContact O-CG 3.38Å; L168-L172 PolarHBondContact O-N 3.2Å; A169-L172 PolarHBondContact O-N 3.45Å; V170-L172 PolarHBondContact O-N 3.17Å; L172-T174 VanDerWaalsContact C-N 3.26Å; L172-T174 PolarHBondContact O-N 2.95Å; L172-A175 PolarHBondContact O-N 3.31Å; L172-A175 VanDerWaalsContact O-N 3.17Å; L172-I176 WeakPolarHBondContact O-CG1 3.37Å; L172-I176 PolarHBondContact O-N 3.25Å
173	A	91.1	Very high	87.9	Confident	22 Å²	22	51.3 Å²	51.3	18%	0.182	30%	0.3	C	S	.	.	H	α-helix	trans	-60.4	-40.1	175.8	0	0	0	0	0	111.3	L156 A169 V170 I176 G177	L156-A173 HydrophobicContact CD1-CB 3.76Å; L156-A173 HydrophobicContact CD2-CB 4.23Å; L156-A173 HydrophobicContact CG-CB 4.05Å; A169-A173 VanDerWaalsContact O-CB 3.3Å; A169-A173 WeakPolarHBondContact O-CB 3.27Å; A169-A173 PolarHBondContact O-N 3.36Å; V170-A173 PolarHBondContact O-N 2.93Å; A173-I176 PolarHBondContact O-N 3.46Å; A173-G177 PolarHBondContact O-N 3.5Å
174	T	90.8	Very high	87.7	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-62	-47.3	173.8	-57.3	0	0	0	0	111.6	S148 L149 G152 V170 K171 L172 I176 G177 I178 L385	S148-T174 WeakPolarHBondContact O-CG2 3.36Å; S148-T174 PolarHBondContact O-OG1 3.45Å; L149-T174 HydrophobicContact CD2-CG2 4.48Å; G152-T174 WeakPolarHBondContact CA-OG1 3.5Å; V170-T174 WeakPolarHBondContact O-CB 3.37Å; V170-T174 PolarHBondContact O-N 3.39Å; V170-T174 PolarHBondContact O-OG1 2.86Å; K171-T174 PolarHBondContact O-N 3.45Å; L172-T174 VanDerWaalsContact C-N 3.26Å; L172-T174 PolarHBondContact O-N 2.95Å; T174-I176 VanDerWaalsContact C-N 3.27Å; T174-I176 PolarHBondContact O-N 3.08Å; T174-G177 PolarHBondContact O-N 2.91Å; T174-G177 VanDerWaalsContact O-N 3.14Å; T174-I178 WeakPolarHBondContact O-CG2 3.43Å; T174-I178 PolarHBondContact O-N 3.45Å; T174-L385 HydrophobicContact CG2-CD1 3.32Å; T174-L385 HydrophobicContact CG2-CG 4.47Å
175	A	92.3	Very high	87.5	Confident	14 Å²	14	45.1 Å²	45.1	12%	0.116	25%	0.253	C	S	.	.	H	α-helix	trans	-59.3	-39.5	179.1	0	0	0	0	0	111.6	K171 L172 I178 S179 I382 F386	K171-A175 WeakPolarHBondContact O-CB 3.47Å; K171-A175 PolarHBondContact O-N 3.38Å; L172-A175 PolarHBondContact O-N 3.31Å; L172-A175 VanDerWaalsContact O-N 3.17Å; A175-I178 VanDerWaalsContact O-CG2 3.29Å; A175-I178 WeakPolarHBondContact O-CG2 3.48Å; A175-S179 VanDerWaalsContact O-CB 3.28Å; A175-S179 WeakPolarHBondContact O-CB 3.4Å; A175-S179 PolarHBondContact O-N 2.78Å; A175-S179 PolarHBondContact O-OG 3.03Å; A175-I382 HydrophobicContact CB-CD1 4.4Å; A175-F386 HydrophobicContact CB-CZ 4.4Å
176	I	91.6	Very high	87	Confident	122 Å²	122	45.8 Å²	45.8	63%	0.626	26%	0.256	S	S	*	.	H	α-helix	trans	-65.2	-47.8	173.9	-65.1	164.9	0	0	0	110.6	L172 A173 T174 S179 F180	L172-I176 WeakPolarHBondContact O-CG1 3.37Å; L172-I176 PolarHBondContact O-N 3.25Å; A173-I176 PolarHBondContact O-N 3.46Å; T174-I176 VanDerWaalsContact C-N 3.27Å; T174-I176 PolarHBondContact O-N 3.08Å; I176-S179 PolarHBondContact O-N 2.94Å; I176-F180 WeakPolarHBondContact O-CB 3.23Å; I176-F180 PolarHBondContact O-N 3.41Å
177	G	87.8	Confident	86.3	Confident	10 Å²	10	50.8 Å²	50.8	10%	0.103	27%	0.267	C	S	.	.	H	α-helix	trans	-60.5	-46.3	-179.8	0	0	0	0	0	113.3	A173 T174 F180 I181	A173-G177 PolarHBondContact O-N 3.5Å; T174-G177 PolarHBondContact O-N 2.91Å; T174-G177 VanDerWaalsContact O-N 3.14Å; G177-F180 PolarHBondContact O-N 2.9Å; G177-I181 WeakPolarHBondContact O-CG1 3.24Å; G177-I181 PolarHBondContact O-N 2.98Å
178	I	87.5	Confident	85.4	Confident	1 Å²	1	50 Å²	50	1%	0.005	26%	0.257	C	S	.	.	H	α-helix	trans	-66.4	-44.5	176.9	-166.5	169.7	0	0	0	110.9	T174 A175 F180 I181 Y182 M336 Y378 T381 I382	T174-I178 WeakPolarHBondContact O-CG2 3.43Å; T174-I178 PolarHBondContact O-N 3.45Å; A175-I178 VanDerWaalsContact O-CG2 3.29Å; A175-I178 WeakPolarHBondContact O-CG2 3.48Å; I178-F180 PolarHBondContact O-N 3.11Å; I178-I181 PolarHBondContact O-N 2.89Å; I178-I181 VanDerWaalsContact O-N 3.12Å; I178-Y182 HydrophobicContact CD1-CD2 4.42Å; I178-Y182 HydrophobicContact CD1-CE2 3.84Å; I178-Y182 HydrophobicContact CG1-CD2 3.61Å; I178-Y182 HydrophobicContact CG1-CE2 3.52Å; I178-Y182 VanDerWaalsContact O-CD2 3.27Å; I178-Y182 WeakPolarHBondContact O-CD2 3.22Å; I178-Y182 PolarHBondContact O-N 3.38Å; I178-M336 HydrophobicContact CB-CE 3.78Å; I178-M336 HydrophobicContact CD1-CE 4.16Å; I178-M336 HydrophobicContact CG1-CE 3.64Å; I178-Y378 HydrophobicContact CG2-CE2 4.41Å; I178-T381 HydrophobicContact CD1-CG2 3.37Å; I178-I382 HydrophobicContact CG2-CD1 3.66Å
179	S	89.5	Confident	84.2	Confident	30 Å²	30	45.8 Å²	45.8	21%	0.21	24%	0.235	C	C	.	.	H	α-helix	trans	-54.7	-44.2	175.6	-59.6	0	0	0	0	111.6	A175 I176 Y182 I183 Y378	A175-S179 VanDerWaalsContact O-CB 3.28Å; A175-S179 WeakPolarHBondContact O-CB 3.4Å; A175-S179 PolarHBondContact O-N 2.78Å; A175-S179 PolarHBondContact O-OG 3.03Å; I176-S179 PolarHBondContact O-N 2.94Å; S179-Y182 PolarHBondContact O-N 3.32Å; S179-I183 VanDerWaalsContact O-CG1 3.29Å; S179-I183 WeakPolarHBondContact O-CG1 3.29Å; S179-I183 PolarHBondContact O-N 2.77Å; S179-Y378 PolarHBondContact OG-OH 2.87Å
180	F	86.9	Confident	83	Confident	118 Å²	118	52.4 Å²	52.4	52%	0.518	26%	0.259	S	S	.	.	H	α-helix	trans	-61.8	-47.2	178	-179.4	-111	0	0	0	111.9	I176 G177 I178 Y182 I183 L184	I176-F180 WeakPolarHBondContact O-CB 3.23Å; I176-F180 PolarHBondContact O-N 3.41Å; G177-F180 PolarHBondContact O-N 2.9Å; I178-F180 PolarHBondContact O-N 3.11Å; F180-Y182 VanDerWaalsContact C-N 3.3Å; F180-Y182 PolarHBondContact O-N 3.44Å; F180-I183 PolarHBondContact O-N 2.65Å; F180-L184 HydrophobicContact CD1-CD1 3.82Å; F180-L184 HydrophobicContact CD1-CG 4.45Å; F180-L184 HydrophobicContact CE1-CD1 3.35Å; F180-L184 HydrophobicContact CE1-CG 4.17Å; F180-L184 HydrophobicContact CE2-CD1 4.31Å; F180-L184 HydrophobicContact CE2-CD2 4.43Å; F180-L184 HydrophobicContact CE2-CG 4.29Å; F180-L184 HydrophobicContact CG-CD1 4.47Å; F180-L184 HydrophobicContact CZ-CD1 3.64Å; F180-L184 HydrophobicContact CZ-CD2 4.26Å; F180-L184 HydrophobicContact CZ-CG 4.08Å; F180-L184 WeakPolarHBondContact O-CB 3.41Å; F180-L184 WeakPolarHBondContact O-CG 3.39Å; F180-L184 PolarHBondContact O-N 3.37Å
181	I	81.2	Confident	81.8	Confident	2 Å²	2	60.4 Å²	60.4	1%	0.01	29%	0.287	C	S	.	.	H	α-helix	trans	-60.4	-40.9	176.4	-71.1	162.8	0	0	0	111.5	G177 I178 L184 N185 F333 M336	G177-I181 WeakPolarHBondContact O-CG1 3.24Å; G177-I181 PolarHBondContact O-N 2.98Å; I178-I181 PolarHBondContact O-N 2.89Å; I178-I181 VanDerWaalsContact O-N 3.12Å; I181-L184 PolarHBondContact O-N 3.46Å; I181-N185 WeakPolarHBondContact CG2-ND2 3.38Å; I181-N185 WeakPolarHBondContact O-CB 3.5Å; I181-N185 PolarHBondContact O-N 3.46Å; I181-N185 PolarHBondContact O-ND2 2.73Å; I181-F333 HydrophobicContact CD1-CD2 3.48Å; I181-F333 VanDerWaalsContact CD1-CD2 3.48Å; I181-F333 HydrophobicContact CD1-CE2 3.71Å; I181-F333 HydrophobicContact CD1-CG 4.16Å; I181-F333 HydrophobicContact CG1-CD2 3.61Å; I181-F333 HydrophobicContact CG1-CE2 3.24Å; I181-F333 HydrophobicContact CG1-CG 4.5Å; I181-F333 HydrophobicContact CG1-CZ 3.88Å; I181-M336 HydrophobicContact CD1-CB 4.25Å; I181-M336 HydrophobicContact CD1-CE 3.35Å; I181-M336 HydrophobicContact CD1-SD 3.61Å
182	Y	81.6	Confident	80.4	Confident	7 Å²	7	58.7 Å²	58.7	3%	0.027	28%	0.28	C	S	.	.	H	α-helix	trans	-63.2	-47.2	177.3	-94.1	-93.8	0	0	0	111.6	I178 S179 F180 L184 N185 I186 H340 V374 L377 Y378	I178-Y182 HydrophobicContact CD1-CD2 4.42Å; I178-Y182 HydrophobicContact CD1-CE2 3.84Å; I178-Y182 HydrophobicContact CG1-CD2 3.61Å; I178-Y182 HydrophobicContact CG1-CE2 3.52Å; I178-Y182 VanDerWaalsContact O-CD2 3.27Å; I178-Y182 WeakPolarHBondContact O-CD2 3.22Å; I178-Y182 PolarHBondContact O-N 3.38Å; S179-Y182 PolarHBondContact O-N 3.32Å; F180-Y182 VanDerWaalsContact C-N 3.3Å; F180-Y182 PolarHBondContact O-N 3.44Å; Y182-L184 VanDerWaalsContact C-N 3.3Å; Y182-L184 PolarHBondContact O-N 3.08Å; Y182-N185 PolarHBondContact O-N 2.91Å; Y182-I186 VanDerWaalsContact O-CG1 3.26Å; Y182-I186 WeakPolarHBondContact O-CG1 3.4Å; Y182-I186 PolarHBondContact O-N 2.94Å; Y182-H340 AromaticContact CD1-NE2 3.89Å; Y182-H340 AromaticContact CD2-CE1 3.95Å; Y182-H340 AromaticContact CD2-NE2 3.87Å; Y182-H340 AromaticContact CE1-NE2 3.14Å; Y182-H340 WeakPolarHBondContact CE1-NE2 3.5Å; Y182-H340 AromaticContact CE2-CE1 3.32Å; Y182-H340 WeakPolarHBondContact CE2-CE1 3.46Å; Y182-H340 AromaticContact CE2-NE2 3.21Å; Y182-H340 WeakPolarHBondContact CE2-NE2 3.33Å; Y182-H340 AromaticContact CZ-CE1 3.43Å; Y182-H340 VanDerWaalsContact CZ-CE1 3.43Å; Y182-H340 AromaticContact CZ-NE2 2.82Å; Y182-H340 PolarHBondContact OH-NE2 2.94Å; Y182-V374 HydrophobicContact CD1-CG1 3.23Å; Y182-V374 HydrophobicContact CE1-CB 4.42Å; Y182-V374 HydrophobicContact CE1-CG1 3.43Å; Y182-V374 VanDerWaalsContact CE1-CG1 3.43Å; Y182-V374 WeakPolarHBondContact CE1-O 3.48Å; Y182-V374 HydrophobicContact CG-CG1 4.44Å; Y182-L377 WeakPolarHBondContact OH-CD2 3.41Å; Y182-L377 WeakPolarHBondContact OH-CG 3.41Å; Y182-Y378 AromaticContact CD1-CD2 3.79Å; Y182-Y378 HydrophobicContact CD1-CD2 3.79Å; Y182-Y378 HydrophobicContact CD1-CG 4.03Å; Y182-Y378 AromaticContact CD2-CD2 3.51Å; Y182-Y378 HydrophobicContact CD2-CD2 3.51Å; Y182-Y378 HydrophobicContact CD2-CE2 4.12Å; Y182-Y378 HydrophobicContact CD2-CG 4.49Å; Y182-Y378 AromaticContact CE1-CD2 3.97Å; Y182-Y378 HydrophobicContact CE1-CD2 3.97Å; Y182-Y378 HydrophobicContact CE1-CG 4.09Å; Y182-Y378 AromaticContact CE2-CD2 3.61Å; Y182-Y378 HydrophobicContact CE2-CD2 3.61Å; Y182-Y378 HydrophobicContact CE2-CE2 4.48Å; Y182-Y378 HydrophobicContact CE2-CG 4.47Å; Y182-Y378 AromaticContact CG-CD2 3.55Å; Y182-Y378 HydrophobicContact CG-CD2 3.55Å; Y182-Y378 HydrophobicContact CG-CE2 4.25Å; Y182-Y378 HydrophobicContact CG-CG 4.23Å; Y182-Y378 AromaticContact CZ-CD2 3.82Å; Y182-Y378 WeakPolarHBondContact OH-CA 3.49Å; Y182-Y378 PolarHBondContact OH-N 3.45Å
183	I	83.5	Confident	79	Confident	88 Å²	88	58.5 Å²	58.5	45%	0.451	28%	0.277	S	S	.	.	H	α-helix	trans	-60.4	-42.5	176.6	-68.7	165.3	0	0	0	110.8	S179 F180 I186 R187	S179-I183 VanDerWaalsContact O-CG1 3.29Å; S179-I183 WeakPolarHBondContact O-CG1 3.29Å; S179-I183 PolarHBondContact O-N 2.77Å; F180-I183 PolarHBondContact O-N 2.65Å; I183-I186 PolarHBondContact O-N 2.99Å; I183-R187 WeakPolarHBondContact O-CG 3.18Å; I183-R187 PolarHBondContact O-N 2.89Å; I183-R187 VanDerWaalsContact O-N 3.16Å
184	L	79.4	Confident	77.9	Confident	41 Å²	41	62.4 Å²	62.4	22%	0.215	29%	0.294	C	S	.	.	H	α-helix	trans	-61.3	-50.3	176.1	-73.8	-178.8	0	0	0	111	F180 I181 Y182 I186 R187 I188 I192 F333	F180-L184 HydrophobicContact CD1-CD1 3.82Å; F180-L184 HydrophobicContact CD1-CG 4.45Å; F180-L184 HydrophobicContact CE1-CD1 3.35Å; F180-L184 HydrophobicContact CE1-CG 4.17Å; F180-L184 HydrophobicContact CE2-CD1 4.31Å; F180-L184 HydrophobicContact CE2-CD2 4.43Å; F180-L184 HydrophobicContact CE2-CG 4.29Å; F180-L184 HydrophobicContact CG-CD1 4.47Å; F180-L184 HydrophobicContact CZ-CD1 3.64Å; F180-L184 HydrophobicContact CZ-CD2 4.26Å; F180-L184 HydrophobicContact CZ-CG 4.08Å; F180-L184 WeakPolarHBondContact O-CB 3.41Å; F180-L184 WeakPolarHBondContact O-CG 3.39Å; F180-L184 PolarHBondContact O-N 3.37Å; I181-L184 PolarHBondContact O-N 3.46Å; Y182-L184 VanDerWaalsContact C-N 3.3Å; Y182-L184 PolarHBondContact O-N 3.08Å; L184-I186 PolarHBondContact O-N 3.09Å; L184-R187 PolarHBondContact O-N 2.94Å; L184-I188 PolarHBondContact O-N 2.88Å; L184-I192 HydrophobicContact CB-CD1 3.64Å; L184-I192 HydrophobicContact CB-CG1 4.38Å; L184-I192 WeakPolarHBondContact O-CD1 3.47Å; L184-F333 HydrophobicContact CD1-CZ 4.21Å
185	N	76.6	Confident	76.8	Confident	12 Å²	12	64.2 Å²	64.2	6%	0.064	31%	0.306	C	S	.	.	H	α-helix	trans	-58.6	-32.7	-179.7	-90.5	-75.7	0	0	0	112.6	I181 Y182 V189 I192 N337	I181-N185 WeakPolarHBondContact CG2-ND2 3.38Å; I181-N185 WeakPolarHBondContact O-CB 3.5Å; I181-N185 PolarHBondContact O-N 3.46Å; I181-N185 PolarHBondContact O-ND2 2.73Å; Y182-N185 PolarHBondContact O-N 2.91Å; N185-V189 VanDerWaalsContact O-CG2 3.3Å; N185-V189 WeakPolarHBondContact O-CG2 3.46Å; N185-I192 VanDerWaalsContact CA-CD1 3.47Å; N185-I192 HydrophobicContact CB-CD1 4.42Å; N185-I192 VanDerWaalsContact N-CD1 3.3Å; N185-N337 PolarHBondContact ND2-OD1 3.24Å; N185-N337 PolarHBondContact OD1-OD1 3.43Å; N185-N337 VanDerWaalsContact OD1-OD1 3.1Å
186	I	76.3	Confident	75.5	Confident	36 Å²	36	64.1 Å²	64.1	19%	0.185	31%	0.305	C	S	.	.	H	α-helix	trans	-74.5	-27.8	175.9	-67.4	169	0	0	0	111.9	Y182 I183 L184 R367 L371 V374	Y182-I186 VanDerWaalsContact O-CG1 3.26Å; Y182-I186 WeakPolarHBondContact O-CG1 3.4Å; Y182-I186 PolarHBondContact O-N 2.94Å; I183-I186 PolarHBondContact O-N 2.99Å; L184-I186 PolarHBondContact O-N 3.09Å; I186-R367 VanDerWaalsContact CG2-NH1 3.28Å; I186-R367 WeakPolarHBondContact O-CD 3.46Å; I186-R367 PolarHBondContact O-NH1 2.76Å; I186-L371 HydrophobicContact CB-CD1 4.24Å; I186-L371 HydrophobicContact CD1-CD1 3.69Å; I186-L371 HydrophobicContact CG1-CD1 3.57Å; I186-L371 HydrophobicContact CG2-CD1 3.72Å; I186-V374 HydrophobicContact CD1-CG1 4.01Å; I186-V374 HydrophobicContact CG1-CG1 4.02Å
187	R	74.8	Confident	74.4	Confident	167 Å²	167	65.8 Å²	65.8	63%	0.63	31%	0.305	S	S	*	.	H	α-helix	trans	-100.7	-40.4	-172.4	-72.7	-175	174.1	-174.1	-1	115	I183 L184	I183-R187 WeakPolarHBondContact O-CG 3.18Å; I183-R187 PolarHBondContact O-N 2.89Å; I183-R187 VanDerWaalsContact O-N 3.16Å; L184-R187 PolarHBondContact O-N 2.94Å
188	I	68.3	Low	73.6	Confident	88 Å²	88	71 Å²	71	45%	0.451	33%	0.325	S	S	.	.			trans	-142.6	65.8	-164.6	-38.2	179.6	0	0	0	113.3	L184 K190 W191 I192	L184-I188 PolarHBondContact O-N 2.88Å; I188-K190 PolarHBondContact O-N 2.78Å; I188-W191 HydrophobicContact CB-CB 4.44Å; I188-W191 HydrophobicContact CG2-CB 3.57Å; I188-W191 HydrophobicContact CG2-CG 4.36Å; I188-W191 PolarHBondContact O-N 2.74Å; I188-I192 VanDerWaalsContact O-CD1 3.32Å; I188-I192 WeakPolarHBondContact O-CD1 3.41Å; I188-I192 VanDerWaalsContact O-CG1 3.31Å; I188-I192 WeakPolarHBondContact O-CG1 3.28Å; I188-I192 PolarHBondContact O-N 3.04Å
189	V	65.3	Low	72.7	Confident	23 Å²	23	71 Å²	71	14%	0.139	33%	0.326	C	S	.	.	H	α-helix	trans	-60	-42.4	-175.2	159.6	0	0	0	0	114.8	N185 W191 I192 E193 F341 T369	N185-V189 VanDerWaalsContact O-CG2 3.3Å; N185-V189 WeakPolarHBondContact O-CG2 3.46Å; V189-W191 VanDerWaalsContact C-N 3.29Å; V189-W191 PolarHBondContact O-N 3.48Å; V189-I192 PolarHBondContact O-N 3.45Å; V189-I192 VanDerWaalsContact O-N 3.15Å; V189-E193 PolarHBondContact O-N 3.25Å; V189-F341 HydrophobicContact CG1-CE1 3.88Å; V189-F341 HydrophobicContact CG1-CZ 3.91Å; V189-F341 HydrophobicContact CG2-CE1 4.37Å; V189-F341 HydrophobicContact CG2-CZ 4.3Å; V189-T369 HydrophobicContact CB-CG2 3.99Å; V189-T369 HydrophobicContact CG2-CG2 3.21Å
190	K	65.8	Low	71.7	Confident	169 Å²	169	71.7 Å²	71.7	74%	0.735	33%	0.327	S	S	*	.	H	α-helix	trans	-61.5	-36.1	-178.2	-70.8	-177.8	179.3	175.6	0	113.2	I188 N194	I188-K190 PolarHBondContact O-N 2.78Å; K190-N194 PolarHBondContact O-N 2.98Å
191	W	63.2	Low	71	Confident	185 Å²	185	71.4 Å²	71.4	70%	0.701	33%	0.325	S	S	*	.	H	α-helix	trans	-74	-34.8	179.9	-130.9	78.9	0	0	0	110.9	I188 V189 N194 V195	I188-W191 HydrophobicContact CB-CB 4.44Å; I188-W191 HydrophobicContact CG2-CB 3.57Å; I188-W191 HydrophobicContact CG2-CG 4.36Å; I188-W191 PolarHBondContact O-N 2.74Å; V189-W191 VanDerWaalsContact C-N 3.29Å; V189-W191 PolarHBondContact O-N 3.48Å; W191-N194 WeakPolarHBondContact O-CB 3.33Å; W191-N194 PolarHBondContact O-N 3.4Å; W191-V195 HydrophobicContact CE3-CG2 3.83Å; W191-V195 HydrophobicContact CZ3-CG2 4.08Å; W191-V195 VanDerWaalsContact O-CG2 3.31Å; W191-V195 WeakPolarHBondContact O-CG2 3.24Å; W191-V195 PolarHBondContact O-N 2.89Å
192	I	62.8	Low	70.6	Confident	10 Å²	10	72.8 Å²	72.8	5%	0.051	33%	0.332	C	S	.	.	H	α-helix	trans	-71.8	-36	-178.8	-72.2	167.7	0	0	0	112.2	L184 N185 I188 V189 N194 V195 G196 N337 F341	L184-I192 HydrophobicContact CB-CD1 3.64Å; L184-I192 HydrophobicContact CB-CG1 4.38Å; L184-I192 WeakPolarHBondContact O-CD1 3.47Å; N185-I192 VanDerWaalsContact CA-CD1 3.47Å; N185-I192 HydrophobicContact CB-CD1 4.42Å; N185-I192 VanDerWaalsContact N-CD1 3.3Å; I188-I192 VanDerWaalsContact O-CD1 3.32Å; I188-I192 WeakPolarHBondContact O-CD1 3.41Å; I188-I192 VanDerWaalsContact O-CG1 3.31Å; I188-I192 WeakPolarHBondContact O-CG1 3.28Å; I188-I192 PolarHBondContact O-N 3.04Å; V189-I192 PolarHBondContact O-N 3.45Å; V189-I192 VanDerWaalsContact O-N 3.15Å; I192-N194 VanDerWaalsContact C-N 3.35Å; I192-V195 PolarHBondContact O-N 3.32Å; I192-G196 PolarHBondContact O-N 2.99Å; I192-N337 HydrophobicContact CG2-CB 4.45Å; I192-N337 WeakPolarHBondContact CG2-ND2 3.45Å; I192-N337 WeakPolarHBondContact CG2-OD1 3.44Å; I192-N337 PolarHBondContact O-ND2 3.49Å; I192-N337 VanDerWaalsContact O-ND2 3.14Å; I192-F341 HydrophobicContact CG2-CE2 4.12Å; I192-F341 HydrophobicContact CG2-CZ 4.45Å
193	E	64	Low	69.9	Low	83 Å²	83	72.9 Å²	72.9	39%	0.388	33%	0.334	S	S	.	.	H	α-helix	trans	-59.1	-47.1	168.4	-71.6	-178.1	171.2	0	0	110.9	V189 V195 G196 Y197 F341	V189-E193 PolarHBondContact O-N 3.25Å; E193-V195 PolarHBondContact O-N 3.02Å; E193-G196 PolarHBondContact O-N 3.02Å; E193-G196 VanDerWaalsContact O-N 3.15Å; E193-Y197 HydrophobicContact CB-CE2 4.45Å; E193-Y197 WeakPolarHBondContact O-CD2 3.31Å; E193-Y197 PolarHBondContact O-N 3.47Å; E193-F341 HydrophobicContact CG-CE2 4.31Å; E193-F341 HydrophobicContact CG-CZ 4.08Å
194	N	67.6	Low	69.3	Low	104 Å²	104	72.1 Å²	72.1	56%	0.556	33%	0.33	S	S	*	.	H	α-helix	trans	-62	-40.5	177.2	-69.4	-12.3	0	0	0	112.6	K190 W191 I192 G196 Y197 F198	K190-N194 PolarHBondContact O-N 2.98Å; W191-N194 WeakPolarHBondContact O-CB 3.33Å; W191-N194 PolarHBondContact O-N 3.4Å; I192-N194 VanDerWaalsContact C-N 3.35Å; N194-G196 VanDerWaalsContact C-N 3.34Å; N194-Y197 PolarHBondContact O-N 3.4Å; N194-F198 WeakPolarHBondContact O-CB 3.17Å; N194-F198 PolarHBondContact O-N 3.37Å
195	V	66.6	Low	69.1	Low	39 Å²	39	76.7 Å²	76.7	24%	0.236	35%	0.345	C	S	.	.	H	α-helix	trans	-63.2	-41	174	172.1	0	0	0	0	110.7	W191 I192 E193 Y197 F198 T199 F333	W191-V195 HydrophobicContact CE3-CG2 3.83Å; W191-V195 HydrophobicContact CZ3-CG2 4.08Å; W191-V195 VanDerWaalsContact O-CG2 3.31Å; W191-V195 WeakPolarHBondContact O-CG2 3.24Å; W191-V195 PolarHBondContact O-N 2.89Å; I192-V195 PolarHBondContact O-N 3.32Å; E193-V195 PolarHBondContact O-N 3.02Å; V195-Y197 PolarHBondContact O-N 2.93Å; V195-F198 PolarHBondContact O-N 3.05Å; V195-T199 WeakPolarHBondContact O-CB 3.4Å; V195-T199 PolarHBondContact O-N 2.87Å; V195-T199 PolarHBondContact O-OG1 2.75Å; V195-T199 VanDerWaalsContact O-OG1 3.04Å; V195-F333 HydrophobicContact CG1-CD1 4.19Å; V195-F333 HydrophobicContact CG1-CE1 3.75Å
196	G	65.3	Low	68.8	Low	11 Å²	11	77.1 Å²	77.1	11%	0.113	35%	0.347	C	S	.	.	H	α-helix	trans	-60.2	-43.8	174.8	0	0	0	0	0	113	I192 E193 N194 T199 N200	I192-G196 PolarHBondContact O-N 2.99Å; E193-G196 PolarHBondContact O-N 3.02Å; E193-G196 VanDerWaalsContact O-N 3.15Å; N194-G196 VanDerWaalsContact C-N 3.34Å; G196-T199 PolarHBondContact O-N 3.23Å; G196-N200 WeakPolarHBondContact O-CB 3.34Å; G196-N200 PolarHBondContact O-N 3.29Å
197	Y	68.1	Low	68.5	Low	158 Å²	158	76 Å²	76	62%	0.62	34%	0.341	S	S	*	.	H	α-helix	trans	-62	-43.2	173.9	-71.2	-64.9	0	0	0	112.1	E193 N194 V195 N200 F201	E193-Y197 HydrophobicContact CB-CE2 4.45Å; E193-Y197 WeakPolarHBondContact O-CD2 3.31Å; E193-Y197 PolarHBondContact O-N 3.47Å; N194-Y197 PolarHBondContact O-N 3.4Å; V195-Y197 PolarHBondContact O-N 2.93Å; Y197-N200 PolarHBondContact O-N 2.85Å; Y197-F201 WeakPolarHBondContact O-CB 3.19Å; Y197-F201 PolarHBondContact O-N 3.3Å
198	F	71.6	Confident	68.4	Low	118 Å²	118	71.8 Å²	71.8	52%	0.518	33%	0.33	S	S	.	.	H	α-helix	trans	-62.6	-45.1	176.9	179.7	-108	0	0	0	111.9	N194 V195 N200 F201 L202	N194-F198 WeakPolarHBondContact O-CB 3.17Å; N194-F198 PolarHBondContact O-N 3.37Å; V195-F198 PolarHBondContact O-N 3.05Å; F198-N200 PolarHBondContact O-N 3.03Å; F198-F201 WeakPolarHBondContact O-CB 3.36Å; F198-F201 PolarHBondContact O-N 3.48Å; F198-L202 HydrophobicContact CD1-CD1 3.88Å; F198-L202 HydrophobicContact CD1-CG 4.46Å; F198-L202 HydrophobicContact CE1-CD1 3.4Å; F198-L202 VanDerWaalsContact CE1-CD1 3.4Å; F198-L202 HydrophobicContact CE1-CG 4.14Å; F198-L202 HydrophobicContact CE2-CG 4.46Å; F198-L202 HydrophobicContact CZ-CD1 3.78Å; F198-L202 HydrophobicContact CZ-CD2 4.25Å; F198-L202 HydrophobicContact CZ-CG 4.13Å; F198-L202 WeakPolarHBondContact O-CG 3.43Å; F198-L202 PolarHBondContact O-N 3.27Å
199	T	68.5	Low	68.6	Low	3 Å²	3	71.6 Å²	71.6	2%	0.018	33%	0.33	C	S	.	.	H	α-helix	trans	-61.1	-44.4	175.2	-61.6	0	0	0	0	112.2	V195 G196 F201 L202 N203 L330	V195-T199 WeakPolarHBondContact O-CB 3.4Å; V195-T199 PolarHBondContact O-N 2.87Å; V195-T199 PolarHBondContact O-OG1 2.75Å; V195-T199 VanDerWaalsContact O-OG1 3.04Å; G196-T199 PolarHBondContact O-N 3.23Å; T199-F201 VanDerWaalsContact C-N 3.3Å; T199-F201 PolarHBondContact O-N 3.31Å; T199-L202 WeakPolarHBondContact O-CB 3.48Å; T199-L202 PolarHBondContact O-N 2.96Å; T199-N203 PolarHBondContact O-N 2.7Å; T199-L330 WeakPolarHBondContact CG2-O 2.93Å
200	N	68.1	Low	68.8	Low	43 Å²	43	71.1 Å²	71.1	23%	0.23	33%	0.326	C	S	.	.	H	α-helix	trans	-63	-39.9	177.5	-78.6	-19.9	0	0	0	111.7	G196 Y197 F198 N203 L204	G196-N200 WeakPolarHBondContact O-CB 3.34Å; G196-N200 PolarHBondContact O-N 3.29Å; Y197-N200 PolarHBondContact O-N 2.85Å; F198-N200 PolarHBondContact O-N 3.03Å; N200-N203 PolarHBondContact O-N 2.99Å; N200-L204 WeakPolarHBondContact O-CG 3.46Å; N200-L204 PolarHBondContact O-N 2.98Å
201	F	73.7	Confident	69	Low	113 Å²	113	65.2 Å²	65.2	50%	0.496	30%	0.303	S	S	.	.	H	α-helix	trans	-60.3	-46	172.9	176	-99.7	0	0	0	111.2	Y197 F198 T199 N203 L204 W205	Y197-F201 WeakPolarHBondContact O-CB 3.19Å; Y197-F201 PolarHBondContact O-N 3.3Å; F198-F201 WeakPolarHBondContact O-CB 3.36Å; F198-F201 PolarHBondContact O-N 3.48Å; T199-F201 VanDerWaalsContact C-N 3.3Å; T199-F201 PolarHBondContact O-N 3.31Å; F201-N203 VanDerWaalsContact C-N 3.34Å; F201-N203 PolarHBondContact O-N 3.45Å; F201-L204 PolarHBondContact O-N 2.67Å; F201-W205 AromaticContact CD1-CD1 3.55Å; F201-W205 AromaticContact CD1-NE1 3.92Å; F201-W205 AromaticContact CD2-CD1 3.85Å; F201-W205 AromaticContact CD2-NE1 3.86Å; F201-W205 AromaticContact CE1-CD1 3.3Å; F201-W205 HydrophobicContact CE1-CG 4.43Å; F201-W205 AromaticContact CE1-NE1 3.23Å; F201-W205 AromaticContact CE2-CD1 3.63Å; F201-W205 AromaticContact CE2-NE1 3.16Å; F201-W205 AromaticContact CG-CD1 3.85Å; F201-W205 AromaticContact CZ-CD1 3.4Å; F201-W205 AromaticContact CZ-CE2 3.92Å; F201-W205 AromaticContact CZ-NE1 2.83Å; F201-W205 VanDerWaalsContact O-CD1 3.28Å; F201-W205 PolarHBondContact O-N 3.32Å
202	L	70.8	Confident	69.6	Low	30 Å²	30	61 Å²	61	16%	0.157	29%	0.293	C	S	.	.	H	α-helix	trans	-60.6	-40.2	175.8	-71.6	177.4	0	0	0	112.9	F198 T199 W205 L206 F327 L330	F198-L202 HydrophobicContact CD1-CD1 3.88Å; F198-L202 HydrophobicContact CD1-CG 4.46Å; F198-L202 HydrophobicContact CE1-CD1 3.4Å; F198-L202 VanDerWaalsContact CE1-CD1 3.4Å; F198-L202 HydrophobicContact CE1-CG 4.14Å; F198-L202 HydrophobicContact CE2-CG 4.46Å; F198-L202 HydrophobicContact CZ-CD1 3.78Å; F198-L202 HydrophobicContact CZ-CD2 4.25Å; F198-L202 HydrophobicContact CZ-CG 4.13Å; F198-L202 WeakPolarHBondContact O-CG 3.43Å; F198-L202 PolarHBondContact O-N 3.27Å; T199-L202 WeakPolarHBondContact O-CB 3.48Å; T199-L202 PolarHBondContact O-N 2.96Å; L202-W205 WeakPolarHBondContact O-CB 3.42Å; L202-W205 PolarHBondContact O-N 2.92Å; L202-L206 WeakPolarHBondContact O-CB 3.36Å; L202-L206 PolarHBondContact O-N 2.86Å; L202-F327 HydrophobicContact CB-CD1 4.42Å; L202-F327 HydrophobicContact CD1-CD1 4.18Å; L202-F327 HydrophobicContact CD1-CE1 3.95Å; L202-F327 HydrophobicContact CD2-CE1 3.81Å; L202-F327 HydrophobicContact CG-CE1 4.31Å; L202-L330 HydrophobicContact CD1-CD1 4.28Å
203	N	68.4	Low	70.1	Confident	10 Å²	10	62 Å²	62	5%	0.053	30%	0.298	C	S	.	.	H	α-helix	trans	-60.9	-45.6	175.5	-78.1	-18.3	0	0	0	112.2	T199 N200 F201 W205 L206 I207 S331	T199-N203 PolarHBondContact O-N 2.7Å; N200-N203 PolarHBondContact O-N 2.99Å; F201-N203 VanDerWaalsContact C-N 3.34Å; F201-N203 PolarHBondContact O-N 3.45Å; N203-W205 VanDerWaalsContact C-N 3.31Å; N203-W205 PolarHBondContact O-N 3.12Å; N203-L206 PolarHBondContact O-N 3.29Å; N203-I207 WeakPolarHBondContact O-CG1 3.26Å; N203-I207 PolarHBondContact O-N 3.45Å; N203-I207 VanDerWaalsContact O-N 3.11Å; N203-S331 PolarHBondContact ND2-OG 3.37Å; N203-S331 WeakPolarHBondContact OD1-CB 3.4Å; N203-S331 PolarHBondContact OD1-OG 3.41Å
204	L	70.6	Confident	70.4	Confident	72 Å²	72	58.3 Å²	58.3	38%	0.377	28%	0.281	S	S	.	.	H	α-helix	trans	-64	-38.8	176.7	-69.9	172.6	0	0	0	111.4	V59 N200 F201 I207 L208	V59-L204 HydrophobicContact CG1-CD2 3.82Å; N200-L204 WeakPolarHBondContact O-CG 3.46Å; N200-L204 PolarHBondContact O-N 2.98Å; F201-L204 PolarHBondContact O-N 2.67Å; L204-I207 PolarHBondContact O-N 3.5Å; L204-L208 WeakPolarHBondContact O-CB 3.34Å; L204-L208 PolarHBondContact O-N 3.24Å
205	W	74.9	Confident	70.9	Confident	137 Å²	137	61.1 Å²	61.1	52%	0.519	28%	0.284	S	S	.	.	H	α-helix	trans	-63.6	-43.6	173.7	-93.3	98.6	0	0	0	113.3	F201 L202 N203 I207 L208 L209	F201-W205 AromaticContact CD1-CD1 3.55Å; F201-W205 AromaticContact CD1-NE1 3.92Å; F201-W205 AromaticContact CD2-CD1 3.85Å; F201-W205 AromaticContact CD2-NE1 3.86Å; F201-W205 AromaticContact CE1-CD1 3.3Å; F201-W205 HydrophobicContact CE1-CG 4.43Å; F201-W205 AromaticContact CE1-NE1 3.23Å; F201-W205 AromaticContact CE2-CD1 3.63Å; F201-W205 AromaticContact CE2-NE1 3.16Å; F201-W205 AromaticContact CG-CD1 3.85Å; F201-W205 AromaticContact CZ-CD1 3.4Å; F201-W205 AromaticContact CZ-CE2 3.92Å; F201-W205 AromaticContact CZ-NE1 2.83Å; F201-W205 VanDerWaalsContact O-CD1 3.28Å; F201-W205 PolarHBondContact O-N 3.32Å; L202-W205 WeakPolarHBondContact O-CB 3.42Å; L202-W205 PolarHBondContact O-N 2.92Å; N203-W205 VanDerWaalsContact C-N 3.31Å; N203-W205 PolarHBondContact O-N 3.12Å; W205-I207 VanDerWaalsContact C-N 3.26Å; W205-I207 PolarHBondContact O-N 2.88Å; W205-L208 HydrophobicContact CE3-CD2 4.17Å; W205-L208 HydrophobicContact CZ3-CD2 4.12Å; W205-L208 PolarHBondContact O-N 3.29Å; W205-L209 WeakPolarHBondContact O-CB 3.29Å; W205-L209 PolarHBondContact O-N 2.93Å
206	L	69.7	Low	71.2	Confident	20 Å²	20	65.3 Å²	65.3	11%	0.105	30%	0.303	C	S	.	.	H	α-helix	trans	-59.1	-42.5	176.7	-178.3	65.2	0	0	0	110.6	F68 L202 N203 L209 L210	F68-L206 HydrophobicContact CZ-CD2 4.16Å; L202-L206 WeakPolarHBondContact O-CB 3.36Å; L202-L206 PolarHBondContact O-N 2.86Å; N203-L206 PolarHBondContact O-N 3.29Å; L206-L209 WeakPolarHBondContact O-CB 3.4Å; L206-L209 PolarHBondContact O-N 3.49Å; L206-L210 VanDerWaalsContact O-CG 3.32Å; L206-L210 WeakPolarHBondContact O-CG 3.49Å; L206-L210 PolarHBondContact O-N 3.06Å
207	I	69.9	Low	71.5	Confident	14 Å²	14	66.5 Å²	66.5	7%	0.072	31%	0.306	C	S	.	.	H	α-helix	trans	-67.7	-43	177	-69.4	169.3	0	0	0	111.4	I63 N203 L204 W205 L209 L210 L211 C285	I63-I207 HydrophobicContact CB-CD1 4.39Å; I63-I207 HydrophobicContact CD1-CD1 3.9Å; I63-I207 HydrophobicContact CG2-CD1 3.1Å; N203-I207 WeakPolarHBondContact O-CG1 3.26Å; N203-I207 PolarHBondContact O-N 3.45Å; N203-I207 VanDerWaalsContact O-N 3.11Å; L204-I207 PolarHBondContact O-N 3.5Å; W205-I207 VanDerWaalsContact C-N 3.26Å; W205-I207 PolarHBondContact O-N 2.88Å; I207-L209 PolarHBondContact O-N 2.92Å; I207-L210 WeakPolarHBondContact O-CB 3.44Å; I207-L210 PolarHBondContact O-N 3.49Å; I207-L210 VanDerWaalsContact O-N 3.15Å; I207-L211 HydrophobicContact CG2-CD1 4.21Å; I207-L211 HydrophobicContact CG2-CG 4.31Å; I207-L211 VanDerWaalsContact O-CG 3.28Å; I207-L211 WeakPolarHBondContact O-CG 3.21Å; I207-L211 PolarHBondContact O-N 3.2Å; I207-C285 HydrophobicContact CG2-CB 4.26Å
208	L	73.4	Confident	71.9	Confident	77 Å²	77	62.6 Å²	62.6	40%	0.403	30%	0.296	S	S	.	.	H	α-helix	trans	-57.4	-42.4	175.3	-177.6	66	0	0	0	111.3	L204 W205 L211 L212	L204-L208 WeakPolarHBondContact O-CB 3.34Å; L204-L208 PolarHBondContact O-N 3.24Å; W205-L208 HydrophobicContact CE3-CD2 4.17Å; W205-L208 HydrophobicContact CZ3-CD2 4.12Å; W205-L208 PolarHBondContact O-N 3.29Å; L208-L211 PolarHBondContact O-N 3.42Å; L208-L212 HydrophobicContact CG-CD1 4.29Å; L208-L212 WeakPolarHBondContact O-CG 3.48Å; L208-L212 PolarHBondContact O-N 3.35Å
209	L	71.4	Confident	72.1	Confident	85 Å²	85	64.4 Å²	64.4	45%	0.445	30%	0.304	S	S	.	.	H	α-helix	trans	-62.5	-45.2	175.6	-174.5	121	0	0	0	111.6	W205 L206 I207 L211 L212 I213	W205-L209 WeakPolarHBondContact O-CB 3.29Å; W205-L209 PolarHBondContact O-N 2.93Å; L206-L209 WeakPolarHBondContact O-CB 3.4Å; L206-L209 PolarHBondContact O-N 3.49Å; I207-L209 PolarHBondContact O-N 2.92Å; L209-L211 VanDerWaalsContact C-N 3.32Å; L209-L211 PolarHBondContact O-N 3.04Å; L209-L212 PolarHBondContact O-N 2.97Å; L209-I213 HydrophobicContact CD2-CD1 3.49Å; L209-I213 VanDerWaalsContact CD2-CD1 3.49Å; L209-I213 HydrophobicContact CG-CD1 3.85Å; L209-I213 WeakPolarHBondContact O-CB 3.44Å; L209-I213 VanDerWaalsContact O-CG1 3.3Å; L209-I213 WeakPolarHBondContact O-CG1 3.45Å; L209-I213 PolarHBondContact O-N 3.08Å
210	L	69.4	Low	72.4	Confident	12 Å²	12	70.7 Å²	70.7	6%	0.063	34%	0.336	C	S	.	.	H	α-helix	trans	-57.8	-43.6	173.7	-69.6	171.7	0	0	0	111.8	L206 I207 L212 I213 N214 T289 F312	L206-L210 VanDerWaalsContact O-CG 3.32Å; L206-L210 WeakPolarHBondContact O-CG 3.49Å; L206-L210 PolarHBondContact O-N 3.06Å; I207-L210 WeakPolarHBondContact O-CB 3.44Å; I207-L210 PolarHBondContact O-N 3.49Å; I207-L210 VanDerWaalsContact O-N 3.15Å; L210-L212 PolarHBondContact O-N 3.19Å; L210-I213 PolarHBondContact O-N 2.91Å; L210-N214 WeakPolarHBondContact O-CB 3.49Å; L210-N214 PolarHBondContact O-N 3.39Å; L210-N214 PolarHBondContact O-ND2 3.13Å; L210-N214 PolarHBondContact O-OD1 3.43Å; L210-T289 HydrophobicContact CD1-CG2 4.3Å; L210-F312 HydrophobicContact CD2-CD1 3.95Å; L210-F312 HydrophobicContact CD2-CE1 3.19Å; L210-F312 HydrophobicContact CD2-CZ 3.75Å
211	L	72.1	Confident	72.5	Confident	46 Å²	46	70.8 Å²	70.8	24%	0.241	35%	0.348	C	S	.	.	H	α-helix	trans	-63.4	-40.6	177.8	-68	177.6	0	0	0	112.5	I207 L208 L209 R215 L288	I207-L211 HydrophobicContact CG2-CD1 4.21Å; I207-L211 HydrophobicContact CG2-CG 4.31Å; I207-L211 VanDerWaalsContact O-CG 3.28Å; I207-L211 WeakPolarHBondContact O-CG 3.21Å; I207-L211 PolarHBondContact O-N 3.2Å; L208-L211 PolarHBondContact O-N 3.42Å; L209-L211 VanDerWaalsContact C-N 3.32Å; L209-L211 PolarHBondContact O-N 3.04Å; L211-R215 PolarHBondContact O-N 3.42Å; L211-R215 VanDerWaalsContact O-N 3.08Å; L211-L288 HydrophobicContact CD2-CB 3.36Å; L211-L288 HydrophobicContact CD2-CD1 3.55Å; L211-L288 HydrophobicContact CD2-CG 4.05Å
212	L	75.8	Confident	72.5	Confident	95 Å²	95	69.5 Å²	69.5	50%	0.497	34%	0.343	S	S	.	.	H	α-helix	trans	-66.7	-45.4	177.6	-72	168.7	0	0	0	111.4	L208 L209 L210 N214 R215 M216	L208-L212 HydrophobicContact CG-CD1 4.29Å; L208-L212 WeakPolarHBondContact O-CG 3.48Å; L208-L212 PolarHBondContact O-N 3.35Å; L209-L212 PolarHBondContact O-N 2.97Å; L210-L212 PolarHBondContact O-N 3.19Å; L212-N214 VanDerWaalsContact C-N 3.35Å; L212-N214 PolarHBondContact O-N 2.99Å; L212-R215 PolarHBondContact O-N 2.92Å; L212-M216 WeakPolarHBondContact O-CG 3.42Å; L212-M216 PolarHBondContact O-N 2.93Å; L212-M216 VanDerWaalsContact O-N 3.07Å
213	I	72.3	Confident	72.8	Confident	31 Å²	31	71 Å²	71	16%	0.159	35%	0.354	C	S	.	.	H	α-helix	trans	-60	-45.5	176.4	-73.3	166.8	0	0	0	110.6	L209 L210 R215 M216 L217 L316	L209-I213 HydrophobicContact CD2-CD1 3.49Å; L209-I213 VanDerWaalsContact CD2-CD1 3.49Å; L209-I213 HydrophobicContact CG-CD1 3.85Å; L209-I213 WeakPolarHBondContact O-CB 3.44Å; L209-I213 VanDerWaalsContact O-CG1 3.3Å; L209-I213 WeakPolarHBondContact O-CG1 3.45Å; L209-I213 PolarHBondContact O-N 3.08Å; L210-I213 PolarHBondContact O-N 2.91Å; I213-R215 VanDerWaalsContact C-N 3.32Å; I213-R215 PolarHBondContact O-N 3.21Å; I213-M216 WeakPolarHBondContact O-CB 3.49Å; I213-M216 PolarHBondContact O-N 2.66Å; I213-M216 VanDerWaalsContact O-N 3.15Å; I213-L217 HydrophobicContact CG2-CD1 3.43Å; I213-L217 VanDerWaalsContact CG2-CD1 3.43Å; I213-L217 WeakPolarHBondContact O-CD1 3.34Å; I213-L217 PolarHBondContact O-N 3.43Å; I213-L316 HydrophobicContact CD1-CD2 4.25Å; I213-L316 HydrophobicContact CG1-CD2 4.48Å; I213-L316 HydrophobicContact CG2-CD1 3.57Å; I213-L316 HydrophobicContact CG2-CD2 3.58Å; I213-L316 HydrophobicContact CG2-CG 4.2Å
214	N	70.6	Confident	73.2	Confident	6 Å²	6	77.2 Å²	77.2	3%	0.032	38%	0.38	C	S	.	.	H	α-helix	trans	-58.2	-45.1	176.2	-71.3	-12.9	0	0	0	112.9	L210 L212 M216 L217 L218 L288 A292	L210-N214 WeakPolarHBondContact O-CB 3.49Å; L210-N214 PolarHBondContact O-N 3.39Å; L210-N214 PolarHBondContact O-ND2 3.13Å; L210-N214 PolarHBondContact O-OD1 3.43Å; L212-N214 VanDerWaalsContact C-N 3.35Å; L212-N214 PolarHBondContact O-N 2.99Å; N214-M216 VanDerWaalsContact C-N 3.26Å; N214-M216 PolarHBondContact O-N 3.09Å; N214-L217 PolarHBondContact O-N 2.93Å; N214-L218 WeakPolarHBondContact O-CB 3.34Å; N214-L218 VanDerWaalsContact O-CG 3.27Å; N214-L218 WeakPolarHBondContact O-CG 3.5Å; N214-L218 PolarHBondContact O-N 3.08Å; N214-L288 PolarHBondContact ND2-O 2.7Å; N214-A292 WeakPolarHBondContact ND2-CB 3.37Å; N214-A292 WeakPolarHBondContact OD1-CA 3.49Å; N214-A292 WeakPolarHBondContact OD1-CB 3.23Å
215	R	77.1	Confident	73.5	Confident	164 Å²	164	76.9 Å²	76.9	62%	0.619	38%	0.379	S	S	*	.	H	α-helix	trans	-59.5	-44.1	178.8	-173.3	173.5	-176.9	-146.4	-4.9	109.9	L211 L212 I213 F219	L211-R215 PolarHBondContact O-N 3.42Å; L211-R215 VanDerWaalsContact O-N 3.08Å; L212-R215 PolarHBondContact O-N 2.92Å; I213-R215 VanDerWaalsContact C-N 3.32Å; I213-R215 PolarHBondContact O-N 3.21Å; R215-F219 HydrophobicContact CG-CD2 3.82Å; R215-F219 HydrophobicContact CG-CE2 3.57Å; R215-F219 WeakPolarHBondContact O-CD2 3.47Å; R215-F219 PolarHBondContact O-N 3.46Å
216	M	73.7	Confident	73.8	Confident	126 Å²	126	72.5 Å²	72.5	62%	0.621	36%	0.364	S	S	*	.	H	α-helix	trans	-62.3	-51	175.8	-68.4	-176.8	65.2	0	0	112.3	L212 I213 N214 L218 F219 L220	L212-M216 WeakPolarHBondContact O-CG 3.42Å; L212-M216 PolarHBondContact O-N 2.93Å; L212-M216 VanDerWaalsContact O-N 3.07Å; I213-M216 WeakPolarHBondContact O-CB 3.49Å; I213-M216 PolarHBondContact O-N 2.66Å; I213-M216 VanDerWaalsContact O-N 3.15Å; N214-M216 VanDerWaalsContact C-N 3.26Å; N214-M216 PolarHBondContact O-N 3.09Å; M216-L218 VanDerWaalsContact C-N 3.32Å; M216-L218 PolarHBondContact O-N 2.95Å; M216-F219 WeakPolarHBondContact O-CB 3.48Å; M216-F219 PolarHBondContact O-N 3.31Å; M216-F219 VanDerWaalsContact O-N 3.1Å; M216-L220 WeakPolarHBondContact O-CD1 3.31Å; M216-L220 PolarHBondContact O-N 3.38Å
217	L	72.4	Confident	74.1	Confident	36 Å²	36	78.3 Å²	78.3	19%	0.188	39%	0.39	C	S	.	.	H	α-helix	trans	-59.3	-40.4	179.8	-80	148.3	0	0	0	112.9	I213 N214 L220 G221 E222 V296 L316	I213-L217 HydrophobicContact CG2-CD1 3.43Å; I213-L217 VanDerWaalsContact CG2-CD1 3.43Å; I213-L217 WeakPolarHBondContact O-CD1 3.34Å; I213-L217 PolarHBondContact O-N 3.43Å; N214-L217 PolarHBondContact O-N 2.93Å; L217-L220 PolarHBondContact O-N 2.87Å; L217-G221 PolarHBondContact O-N 3.41Å; L217-E222 PolarHBondContact O-N 3.37Å; L217-V296 HydrophobicContact CD1-CG2 3.65Å; L217-V296 HydrophobicContact CD2-CG2 4.37Å; L217-L316 HydrophobicContact CD1-CD1 4.35Å
218	L	75.8	Confident	74.5	Confident	76 Å²	76	83.7 Å²	83.7	40%	0.398	42%	0.419	S	S	.	.	H	α-helix	trans	-67	-37.2	175.5	-72.2	169	0	0	0	112	N214 M216 L220 G221 T223 V291 T295	N214-L218 WeakPolarHBondContact O-CB 3.34Å; N214-L218 VanDerWaalsContact O-CG 3.27Å; N214-L218 WeakPolarHBondContact O-CG 3.5Å; N214-L218 PolarHBondContact O-N 3.08Å; M216-L218 VanDerWaalsContact C-N 3.32Å; M216-L218 PolarHBondContact O-N 2.95Å; L218-L220 VanDerWaalsContact C-N 3.29Å; L218-L220 PolarHBondContact O-N 3.47Å; L218-G221 PolarHBondContact O-N 3.43Å; L218-T223 HydrophobicContact CD2-CG2 4.31Å; L218-V291 HydrophobicContact CD1-CG1 4.32Å; L218-T295 HydrophobicContact CD2-CG2 3.89Å; L218-T295 HydrophobicContact CG-CG2 4.29Å
219	F	75.3	Confident	74.8	Confident	157 Å²	157	80.5 Å²	80.5	69%	0.689	40%	0.404	S	S	*	.	H	α-helix	trans	-66.9	-29	172.9	-85.6	-62.4	0	0	0	113.1	R215 M216 G221	R215-F219 HydrophobicContact CG-CD2 3.82Å; R215-F219 HydrophobicContact CG-CE2 3.57Å; R215-F219 WeakPolarHBondContact O-CD2 3.47Å; R215-F219 PolarHBondContact O-N 3.46Å; M216-F219 WeakPolarHBondContact O-CB 3.48Å; M216-F219 PolarHBondContact O-N 3.31Å; M216-F219 VanDerWaalsContact O-N 3.1Å; F219-G221 PolarHBondContact O-N 2.82Å
220	L	75.2	Confident	75.4	Confident	134 Å²	134	82.6 Å²	82.6	70%	0.702	41%	0.41	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.2	-8	174.3	-88.7	79.2	0	0	0	113.2	M216 L217 L218	M216-L220 WeakPolarHBondContact O-CD1 3.31Å; M216-L220 PolarHBondContact O-N 3.38Å; L217-L220 PolarHBondContact O-N 2.87Å; L218-L220 VanDerWaalsContact C-N 3.29Å; L218-L220 PolarHBondContact O-N 3.47Å
221	G	70.6	Confident	75.9	Confident	45 Å²	45	84.5 Å²	84.5	46%	0.464	42%	0.42	S	S	.	.	T	Hydrogen-bonded Turn	trans	82.7	13.9	174.8	0	0	0	0	0	115.3	L217 L218 F219 T223	L217-G221 PolarHBondContact O-N 3.41Å; L218-G221 PolarHBondContact O-N 3.43Å; F219-G221 PolarHBondContact O-N 2.82Å; G221-T223 PolarHBondContact O-N 3.47Å; G221-T223 PolarHBondContact O-OG1 3.27Å
222	E	73.1	Confident	76.1	Confident	87 Å²	87	89.3 Å²	89.3	41%	0.407	45%	0.445	S	S	.	.			trans	-72.7	69.5	177.1	-70.5	-64.7	164.9	0	0	111.6	L217	L217-E222 PolarHBondContact O-N 3.37Å
223	T	76.6	Confident	76.1	Confident	62 Å²	62	89.6 Å²	89.6	38%	0.38	46%	0.455	S	S	.	.			trans	-110.8	7.4	-176.1	55.2	0	0	0	0	113.5	L218 G221 N225 F226	L218-T223 HydrophobicContact CD2-CG2 4.31Å; G221-T223 PolarHBondContact O-N 3.47Å; G221-T223 PolarHBondContact O-OG1 3.27Å; T223-N225 PolarHBondContact O-N 3.02Å; T223-N225 VanDerWaalsContact O-N 3.13Å; T223-F226 WeakPolarHBondContact O-CA 3.26Å; T223-F226 WeakPolarHBondContact O-CB 3.35Å; T223-F226 PolarHBondContact O-N 3.38Å
224	K	76.7	Confident	76.3	Confident	139 Å²	139	94 Å²	94	60%	0.604	47%	0.473	S	S	*	.	G	3₁₀ helix	trans	-53.2	-39.2	-175.9	-65.8	174.9	-177.1	160	0	113.1	F226 E227	K224-F226 PolarHBondContact O-N 2.94Å; K224-E227 PolarHBondContact O-N 2.87Å
225	N	78.5	Confident	76.7	Confident	66 Å²	66	95.2 Å²	95.2	35%	0.353	48%	0.481	S	S	.	.	G	3₁₀ helix	trans	-69.6	-11.3	178.7	-66.5	-26.5	0	0	0	113.8	T223 Y294 M297	T223-N225 PolarHBondContact O-N 3.02Å; T223-N225 VanDerWaalsContact O-N 3.13Å; N225-Y294 WeakPolarHBondContact CB-O 3.22Å; N225-Y294 PolarHBondContact ND2-O 3.39Å; N225-M297 PolarHBondContact ND2-O 3.24Å
226	F	80	Confident	76.7	Confident	45 Å²	45	92 Å²	92	20%	0.197	47%	0.473	C	S	.	.	G	3₁₀ helix	trans	-100.6	-9.4	178	-62.3	-84.5	0	0	0	114.1	V81 L85 T223 K224 N228 A229 V291 T295	V81-F226 HydrophobicContact CG1-CD1 4.34Å; V81-F226 HydrophobicContact CG1-CE1 4.25Å; L85-F226 HydrophobicContact CD1-CE1 4.39Å; T223-F226 WeakPolarHBondContact O-CA 3.26Å; T223-F226 WeakPolarHBondContact O-CB 3.35Å; T223-F226 PolarHBondContact O-N 3.38Å; K224-F226 PolarHBondContact O-N 2.94Å; F226-N228 PolarHBondContact O-N 3.35Å; F226-N228 VanDerWaalsContact O-N 3.16Å; F226-A229 HydrophobicContact CB-CB 4.45Å; F226-A229 HydrophobicContact CD1-CB 4.5Å; F226-A229 VanDerWaalsContact O-CB 3.24Å; F226-A229 WeakPolarHBondContact O-CB 3.48Å; F226-A229 PolarHBondContact O-N 3.41Å; F226-V291 HydrophobicContact CZ-CG1 3.99Å; F226-T295 HydrophobicContact CE2-CG2 3.59Å; F226-T295 HydrophobicContact CZ-CG2 4.12Å
227	E	77.3	Confident	76.9	Confident	141 Å²	141	92.7 Å²	92.7	66%	0.659	48%	0.478	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59	-31.5	-175.8	-70.8	179.2	-179.7	0	0	112.9	K224	K224-E227 PolarHBondContact O-N 2.87Å
228	N	78.4	Confident	77.3	Confident	127 Å²	127	96.1 Å²	96.1	68%	0.679	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.7	34.1	174.3	-67.2	-56	0	0	0	112.6	F226 F230 D231	F226-N228 PolarHBondContact O-N 3.35Å; F226-N228 VanDerWaalsContact O-N 3.16Å; N228-F230 PolarHBondContact O-N 3.11Å; N228-F230 VanDerWaalsContact O-N 3.16Å; N228-D231 PolarHBondContact O-N 3.49Å
229	A	79.5	Confident	77.5	Confident	10 Å²	10	92.7 Å²	92.7	8%	0.083	49%	0.488	C	S	.	.	T	Hydrogen-bonded Turn	trans	-60.4	-28.2	-173.4	0	0	0	0	0	114	S80 V81 G82 F226	S80-A229 PolarHBondContact OG-O 3.05Å; V81-A229 HydrophobicContact CB-CB 4.48Å; G82-A229 VanDerWaalsContact CA-O 3.24Å; G82-A229 WeakPolarHBondContact CA-O 3.34Å; G82-A229 PolarHBondContact N-O 3.31Å; F226-A229 HydrophobicContact CB-CB 4.45Å; F226-A229 HydrophobicContact CD1-CB 4.5Å; F226-A229 VanDerWaalsContact O-CB 3.24Å; F226-A229 WeakPolarHBondContact O-CB 3.48Å; F226-A229 PolarHBondContact O-N 3.41Å
230	F	82.9	Confident	78	Confident	130 Å²	130	86.4 Å²	86.4	57%	0.57	46%	0.461	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.1	30.2	-178	-71.3	-84	0	0	0	113.3	G82 M83 N228 L232	G82-F230 VanDerWaalsContact C-CE1 3.47Å; M83-F230 HydrophobicContact SD-CD1 4.46Å; N228-F230 PolarHBondContact O-N 3.11Å; N228-F230 VanDerWaalsContact O-N 3.16Å; F230-L232 PolarHBondContact O-N 3.49Å
231	D	81.1	Confident	78.5	Confident	52 Å²	52	81.5 Å²	81.5	28%	0.278	44%	0.437	S	S	.	.			trans	-59	101.7	174.9	-175	-0.1	0	0	0	110.6	N228 S233 K234	N228-D231 PolarHBondContact O-N 3.49Å; D231-S233 PolarHBondContact O-N 3.14Å; D231-S233 WeakPolarHBondContact OD1-CB 3.18Å; D231-S233 PolarHBondContact OD1-N 3.07Å; D231-S233 VanDerWaalsContact OD1-N 3.12Å; D231-S233 PolarHBondContact OD1-OG 3.03Å; D231-S233 PolarHBondContact OD2-OG 3.33Å; D231-K234 PolarHBondContact O-N 3.29Å; D231-K234 VanDerWaalsContact OD2-CE 3.31Å; D231-K234 WeakPolarHBondContact OD2-CE 3.36Å
232	L	75.6	Confident	79.1	Confident	147 Å²	147	81.8 Å²	81.8	77%	0.77	43%	0.428	S	S	*	.	G	3₁₀ helix	trans	-66	-22.3	-176.8	-81.5	125.8	0	0	0	112.1	F230 K234 V235	F230-L232 PolarHBondContact O-N 3.49Å; L232-K234 PolarHBondContact O-N 3.25Å; L232-V235 PolarHBondContact O-N 3.24Å
233	S	76.5	Confident	79.8	Confident	100 Å²	100	77.7 Å²	77.7	70%	0.699	41%	0.409	S	S	*	.	G	3₁₀ helix	trans	-66	-25.2	178	72.4	0	0	0	0	112.6	D231	D231-S233 PolarHBondContact O-N 3.14Å; D231-S233 WeakPolarHBondContact OD1-CB 3.18Å; D231-S233 PolarHBondContact OD1-N 3.07Å; D231-S233 VanDerWaalsContact OD1-N 3.12Å; D231-S233 PolarHBondContact OD1-OG 3.03Å; D231-S233 PolarHBondContact OD2-OG 3.33Å
234	K	75.6	Confident	80.4	Confident	125 Å²	125	77.1 Å²	77.1	54%	0.543	40%	0.401	S	S	.	.	G	3₁₀ helix	trans	-93.6	-5.9	179.6	-61.2	-178	-177	177.7	0	113.4	G79 D231 L232 Q236	G79-K234 CarbonylContact C-O 3.59Å; G79-K234 WeakPolarHBondContact CA-O 3.44Å; G79-K234 WeakPolarHBondContact O-CB 3.3Å; D231-K234 PolarHBondContact O-N 3.29Å; D231-K234 VanDerWaalsContact OD2-CE 3.31Å; D231-K234 WeakPolarHBondContact OD2-CE 3.36Å; L232-K234 PolarHBondContact O-N 3.25Å; K234-Q236 PolarHBondContact O-N 3.46Å
235	V	79.2	Confident	80.8	Confident	31 Å²	31	71.5 Å²	71.5	19%	0.188	38%	0.376	C	S	.	.			trans	-74.7	118.3	-175.3	178	0	0	0	0	110.4	M83 L232 L237 M240	M83-V235 HydrophobicContact CB-CG2 4.46Å; M83-V235 HydrophobicContact CG-CB 4.44Å; M83-V235 HydrophobicContact CG-CG1 4.06Å; M83-V235 HydrophobicContact CG-CG2 3.47Å; M83-V235 VanDerWaalsContact CG-CG2 3.47Å; L232-V235 PolarHBondContact O-N 3.24Å; V235-L237 HydrophobicContact CG1-CD1 4.24Å; V235-L237 PolarHBondContact O-N 3.29Å; V235-M240 HydrophobicContact CG1-CE 4.19Å
236	Q	76	Confident	81.2	Confident	97 Å²	97	69.3 Å²	69.3	45%	0.453	37%	0.366	S	S	.	.			trans	-95.5	93.3	178.6	-67	-175.4	2.8	0	0	110.8	S78 K234 S238 G239 M240	S78-Q236 PolarHBondContact O-N 3.38Å; K234-Q236 PolarHBondContact O-N 3.46Å; Q236-S238 PolarHBondContact O-N 3.03Å; Q236-G239 PolarHBondContact O-N 3.18Å; Q236-M240 PolarHBondContact O-N 2.95Å
237	L	79.8	Confident	81.6	Confident	139 Å²	139	67.2 Å²	67.2	73%	0.728	36%	0.357	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.5	-33.4	178.1	-126.7	76.4	0	0	0	112.6	V235 G239 M240	V235-L237 HydrophobicContact CG1-CD1 4.24Å; V235-L237 PolarHBondContact O-N 3.29Å; L237-G239 VanDerWaalsContact C-N 3.28Å; L237-G239 PolarHBondContact O-N 3.45Å; L237-M240 WeakPolarHBondContact O-CB 3.43Å; L237-M240 PolarHBondContact O-N 2.93Å
238	S	79.3	Confident	82.2	Confident	108 Å²	108	60.5 Å²	60.5	76%	0.755	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67	-27.4	175.2	54.1	0	0	0	0	113.1	Q236 P241	Q236-S238 PolarHBondContact O-N 3.03Å; S238-P241 WeakPolarHBondContact O-CD 3.18Å
239	G	81.3	Confident	82.4	Confident	5 Å²	5	55.9 Å²	55.9	5%	0.052	30%	0.299	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.9	-20.8	178	0	0	0	0	0	113.9	H77 Q236 L237 P241 L242 A243	H77-G239 WeakPolarHBondContact CB-O 3.49Å; H77-G239 CarbonylContact O-C 3.57Å; H77-G239 WeakPolarHBondContact O-CA 3.42Å; Q236-G239 PolarHBondContact O-N 3.18Å; L237-G239 VanDerWaalsContact C-N 3.28Å; L237-G239 PolarHBondContact O-N 3.45Å; G239-P241 VanDerWaalsContact C-N 3.33Å; G239-P241 VanDerWaalsContact O-N 3.13Å; G239-L242 WeakPolarHBondContact O-CB 3.24Å; G239-L242 PolarHBondContact O-N 3.04Å; G239-A243 PolarHBondContact O-N 3.23Å; G239-A243 VanDerWaalsContact O-N 3.13Å
240	M	85.8	Confident	82.8	Confident	25 Å²	25	55.5 Å²	55.5	12%	0.123	30%	0.296	C	S	.	.	H	α-helix	trans	-47.1	-44.4	-177.4	-79.4	-66.4	-167.5	0	0	115.1	M83 V87 V235 Q236 L237 L242 A243 F244	M83-M240 HydrophobicContact CB-CE 4.32Å; M83-M240 HydrophobicContact CE-CE 3.3Å; V87-M240 HydrophobicContact CG2-CE 4.44Å; V87-M240 HydrophobicContact CG2-SD 3.82Å; V235-M240 HydrophobicContact CG1-CE 4.19Å; Q236-M240 PolarHBondContact O-N 2.95Å; L237-M240 WeakPolarHBondContact O-CB 3.43Å; L237-M240 PolarHBondContact O-N 2.93Å; M240-L242 VanDerWaalsContact C-N 3.29Å; M240-L242 PolarHBondContact O-N 3.17Å; M240-A243 WeakPolarHBondContact O-CB 3.48Å; M240-A243 PolarHBondContact O-N 3.34Å; M240-A243 VanDerWaalsContact O-N 3.08Å; M240-F244 WeakPolarHBondContact O-CD2 3.19Å; M240-F244 PolarHBondContact O-N 3.32Å
241	P	84.7	Confident	83.1	Confident	30 Å²	30	49.3 Å²	49.3	20%	0.195	27%	0.269	C	S	.	.	H	α-helix	trans	-57.9	-40.9	179	-23.9	35	0	0	0	113.1	S238 G239 F244 Y245 F442 L446	S238-P241 WeakPolarHBondContact O-CD 3.18Å; G239-P241 VanDerWaalsContact C-N 3.33Å; G239-P241 VanDerWaalsContact O-N 3.13Å; P241-F244 PolarHBondContact O-N 3.28Å; P241-Y245 WeakPolarHBondContact O-CB 3.43Å; P241-Y245 PolarHBondContact O-N 3.29Å; P241-F442 HydrophobicContact CB-CE1 4.18Å; P241-F442 HydrophobicContact CB-CZ 3.86Å; P241-F442 HydrophobicContact CG-CZ 4.06Å; P241-L446 HydrophobicContact CB-CD1 3.38Å; P241-L446 HydrophobicContact CB-CD2 3.33Å; P241-L446 HydrophobicContact CB-CG 3.94Å; P241-L446 HydrophobicContact CG-CD2 4.24Å; P241-L446 WeakPolarHBondContact O-CD1 3.37Å
242	L	82.9	Confident	83.2	Confident	52 Å²	52	47.8 Å²	47.8	27%	0.272	26%	0.263	S	S	.	.	H	α-helix	trans	-71.6	-30.3	176.7	-66.8	170.6	0	0	0	112.5	H77 G239 M240 Y245 S246 S450	H77-L242 HydrophobicContact CB-CB 4.28Å; H77-L242 VanDerWaalsContact CE1-CD1 3.5Å; H77-L242 WeakPolarHBondContact CE1-CD1 3.48Å; G239-L242 WeakPolarHBondContact O-CB 3.24Å; G239-L242 PolarHBondContact O-N 3.04Å; M240-L242 VanDerWaalsContact C-N 3.29Å; M240-L242 PolarHBondContact O-N 3.17Å; L242-Y245 PolarHBondContact O-N 3.49Å; L242-S246 PolarHBondContact O-N 3.48Å; L242-S246 PolarHBondContact O-OG 2.83Å; L242-S450 VanDerWaalsContact CD2-OG 3.31Å; L242-S450 WeakPolarHBondContact CD2-OG 3.34Å
243	A	88.4	Confident	83.5	Confident	0 Å²	0	40.8 Å²	40.8	0%	0	23%	0.226	C	C	.	.	H	α-helix	trans	-65.2	-48.2	171.9	0	0	0	0	0	111	I74 H77 V87 G239 M240 Y245 S246 G247	I74-A243 HydrophobicContact CG2-CB 4.49Å; H77-A243 HydrophobicContact CB-CB 3.8Å; V87-A243 HydrophobicContact CG1-CB 4.22Å; G239-A243 PolarHBondContact O-N 3.23Å; G239-A243 VanDerWaalsContact O-N 3.13Å; M240-A243 WeakPolarHBondContact O-CB 3.48Å; M240-A243 PolarHBondContact O-N 3.34Å; M240-A243 VanDerWaalsContact O-N 3.08Å; A243-Y245 VanDerWaalsContact C-N 3.3Å; A243-Y245 PolarHBondContact O-N 3.26Å; A243-S246 PolarHBondContact O-N 3.43Å; A243-G247 PolarHBondContact O-N 3.09Å
244	F	89.1	Confident	84.1	Confident	50 Å²	50	36 Å²	36	22%	0.219	19%	0.193	C	C	.	.	H	α-helix	trans	-62.2	-38.5	174.7	-84.6	-81.3	0	0	0	112	V87 A90 L94 M240 P241 S246 G247 M248 M443	V87-F244 HydrophobicContact CG1-CD1 4.42Å; V87-F244 HydrophobicContact CG1-CG 4.42Å; V87-F244 HydrophobicContact CG2-CE2 4.38Å; A90-F244 HydrophobicContact CB-CE1 3.58Å; A90-F244 HydrophobicContact CB-CZ 3.86Å; L94-F244 HydrophobicContact CD1-CD1 4.11Å; L94-F244 HydrophobicContact CD1-CE1 4Å; M240-F244 WeakPolarHBondContact O-CD2 3.19Å; M240-F244 PolarHBondContact O-N 3.32Å; P241-F244 PolarHBondContact O-N 3.28Å; F244-S246 VanDerWaalsContact C-N 3.34Å; F244-S246 PolarHBondContact O-N 2.96Å; F244-G247 PolarHBondContact O-N 2.69Å; F244-M248 VanDerWaalsContact O-CB 3.3Å; F244-M248 WeakPolarHBondContact O-CB 3.44Å; F244-M248 WeakPolarHBondContact O-CG 3.36Å; F244-M248 PolarHBondContact O-N 3.29Å; F244-M443 HydrophobicContact CB-CE 3.53Å
245	Y	85	Confident	84.6	Confident	21 Å²	21	30.7 Å²	30.7	8%	0.082	17%	0.17	C	C	.	.	H	α-helix	trans	-58.2	-46.4	174.6	175.9	-98.7	0	0	0	112	P241 L242 A243 Y249 L394 N395 S398 M443 S447	P241-Y245 WeakPolarHBondContact O-CB 3.43Å; P241-Y245 PolarHBondContact O-N 3.29Å; L242-Y245 PolarHBondContact O-N 3.49Å; A243-Y245 VanDerWaalsContact C-N 3.3Å; A243-Y245 PolarHBondContact O-N 3.26Å; Y245-Y249 PolarHBondContact O-N 2.87Å; Y245-L394 PolarHBondContact OH-O 2.86Å; Y245-N395 VanDerWaalsContact CE1-OD1 3.28Å; Y245-N395 WeakPolarHBondContact CE1-OD1 3.19Å; Y245-N395 VanDerWaalsContact OH-CA 3.24Å; Y245-N395 WeakPolarHBondContact OH-CA 3.46Å; Y245-N395 PolarHBondContact OH-OD1 3.39Å; Y245-S398 WeakPolarHBondContact OH-CB 3.46Å; Y245-S398 PolarHBondContact OH-OG 2.99Å; Y245-M443 HydrophobicContact CD2-SD 4.08Å; Y245-S447 VanDerWaalsContact CE2-OG 3.25Å; Y245-S447 WeakPolarHBondContact CE2-OG 3.38Å
246	S	85.9	Confident	84.7	Confident	21 Å²	21	31.9 Å²	31.9	15%	0.147	17%	0.172	C	C	.	.	H	α-helix	trans	-64.1	-42.8	176.3	-57.8	0	0	0	0	112.1	S70 L242 A243 F244 Y249	S70-S246 WeakPolarHBondContact CB-O 3.23Å; S70-S246 PolarHBondContact OG-O 3.05Å; L242-S246 PolarHBondContact O-N 3.48Å; L242-S246 PolarHBondContact O-OG 2.83Å; A243-S246 PolarHBondContact O-N 3.43Å; F244-S246 VanDerWaalsContact C-N 3.34Å; F244-S246 PolarHBondContact O-N 2.96Å; S246-Y249 WeakPolarHBondContact O-CB 3.41Å; S246-Y249 PolarHBondContact O-N 3.31Å
247	G	90.2	Very high	85.1	Confident	0 Å²	0	27.3 Å²	27.3	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-68.9	-44.9	179	0	0	0	0	0	113.5	A243 F244 Y249 A250 Y251	A243-G247 PolarHBondContact O-N 3.09Å; F244-G247 PolarHBondContact O-N 2.69Å; G247-Y249 PolarHBondContact O-N 2.95Å; G247-A250 WeakPolarHBondContact O-CB 3.26Å; G247-A250 PolarHBondContact O-N 3.46Å; G247-Y251 WeakPolarHBondContact O-CD2 3.24Å; G247-Y251 PolarHBondContact O-N 3.4Å
248	M	88.8	Confident	85.3	Confident	0 Å²	0	20.7 Å²	20.7	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-64.1	-26.2	177.8	-67.5	-65.6	-65.9	0	0	112.1	C91 L94 F244 W402 F436 M443	C91-M248 HydrophobicContact CB-CG 4.48Å; C91-M248 HydrophobicContact CB-SD 3.98Å; L94-M248 HydrophobicContact CB-CE 4.09Å; L94-M248 HydrophobicContact CB-SD 3.84Å; L94-M248 HydrophobicContact CD1-SD 4.38Å; F244-M248 VanDerWaalsContact O-CB 3.3Å; F244-M248 WeakPolarHBondContact O-CB 3.44Å; F244-M248 WeakPolarHBondContact O-CG 3.36Å; F244-M248 PolarHBondContact O-N 3.29Å; M248-W402 HydrophobicContact CB-CH2 3.97Å; M248-W402 HydrophobicContact CB-CZ2 3.55Å; M248-W402 HydrophobicContact CE-CH2 3.49Å; M248-W402 VanDerWaalsContact CE-CH2 3.49Å; M248-W402 HydrophobicContact CE-CZ2 4.27Å; M248-W402 HydrophobicContact CE-CZ3 3.99Å; M248-F436 HydrophobicContact CE-CE2 4.19Å; M248-M443 HydrophobicContact CB-CE 4.45Å; M248-M443 HydrophobicContact CG-CE 3.82Å
249	Y	83.8	Confident	85.3	Confident	31 Å²	31	16.3 Å²	16.3	12%	0.122	8%	0.083	C	C	.	.	H	α-helix	trans	-61.6	-45.3	170	169.7	-102	0	0	0	112.1	Y245 S246 G247 Y251 A252 L394 M397	Y245-Y249 PolarHBondContact O-N 2.87Å; S246-Y249 WeakPolarHBondContact O-CB 3.41Å; S246-Y249 PolarHBondContact O-N 3.31Å; G247-Y249 PolarHBondContact O-N 2.95Å; Y249-Y251 VanDerWaalsContact C-N 3.34Å; Y249-Y251 PolarHBondContact O-N 2.88Å; Y249-A252 WeakPolarHBondContact O-CB 3.45Å; Y249-A252 PolarHBondContact O-N 2.96Å; Y249-L394 HydrophobicContact CD2-CD2 3.83Å; Y249-L394 HydrophobicContact CE1-CD2 4Å; Y249-L394 HydrophobicContact CE2-CD2 3.23Å; Y249-L394 HydrophobicContact CG-CD2 4.5Å; Y249-L394 WeakPolarHBondContact OH-CD2 3.22Å; Y249-M397 HydrophobicContact CD2-CE 4.17Å; Y249-M397 HydrophobicContact CE2-CE 3.47Å; Y249-M397 VanDerWaalsContact CE2-CE 3.47Å
250	A	87.1	Confident	85	Confident	2 Å²	2	16.7 Å²	16.7	2%	0.017	8%	0.084	C	C	.	.	H	α-helix	trans	-63.6	-36.8	179.8	0	0	0	0	0	113	W88 G247 A252 Y286	W88-A250 HydrophobicContact CH2-CB 3.64Å; W88-A250 HydrophobicContact CZ3-CB 3.61Å; G247-A250 WeakPolarHBondContact O-CB 3.26Å; G247-A250 PolarHBondContact O-N 3.46Å; A250-A252 PolarHBondContact O-N 2.87Å; A250-Y286 HydrophobicContact CB-CE2 3.91Å; A250-Y286 PolarHBondContact O-OH 2.89Å; A250-Y286 VanDerWaalsContact O-OH 3.09Å
251	Y	89.2	Confident	84.8	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	8%	0.079	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.4	4.2	-179.8	-75.6	-81.5	0	0	0	114.5	W88 C91 S95 G247 Y249 M279 V282 T283 Y286	W88-Y251 HydrophobicContact CE3-CD2 4.46Å; W88-Y251 AromaticContact CE3-CE2 3.55Å; W88-Y251 HydrophobicContact CE3-CE2 3.55Å; W88-Y251 HydrophobicContact CZ3-CD2 4.42Å; W88-Y251 AromaticContact CZ3-CE2 3.88Å; W88-Y251 HydrophobicContact CZ3-CE2 3.88Å; W88-Y251 WeakPolarHBondContact O-CE2 3.33Å; W88-Y251 PolarHBondContact O-OH 2.85Å; C91-Y251 HydrophobicContact CB-CD2 3.68Å; C91-Y251 HydrophobicContact CB-CE2 3.67Å; S95-Y251 WeakPolarHBondContact OG-CB 3.49Å; G247-Y251 WeakPolarHBondContact O-CD2 3.24Å; G247-Y251 PolarHBondContact O-N 3.4Å; Y249-Y251 VanDerWaalsContact C-N 3.34Å; Y249-Y251 PolarHBondContact O-N 2.88Å; Y251-M279 HydrophobicContact CD1-CE 3.95Å; Y251-V282 HydrophobicContact CD1-CG1 3.88Å; Y251-V282 HydrophobicContact CE1-CG1 3.84Å; Y251-T283 WeakPolarHBondContact CE1-OG1 3.22Å; Y251-Y286 HydrophobicContact CD1-CD2 4.05Å; Y251-Y286 HydrophobicContact CD1-CE2 4.05Å; Y251-Y286 HydrophobicContact CD2-CD2 4.3Å; Y251-Y286 HydrophobicContact CD2-CE2 4.44Å; Y251-Y286 AromaticContact CE1-CD2 3.58Å; Y251-Y286 HydrophobicContact CE1-CD2 3.58Å; Y251-Y286 HydrophobicContact CE1-CE2 4.05Å; Y251-Y286 HydrophobicContact CE1-CG 4.47Å; Y251-Y286 AromaticContact CE2-CD2 3.87Å; Y251-Y286 HydrophobicContact CE2-CD2 3.87Å; Y251-Y286 HydrophobicContact CE2-CE2 4.45Å; Y251-Y286 HydrophobicContact CG-CD2 4.39Å; Y251-Y286 HydrophobicContact CG-CE2 4.25Å; Y251-Y286 AromaticContact CZ-CD2 3.46Å; Y251-Y286 VanDerWaalsContact CZ-CD2 3.46Å
252	A	83.4	Confident	84.5	Confident	19 Å²	19	16.7 Å²	16.7	16%	0.157	8%	0.081	C	C	.	.	T	Hydrogen-bonded Turn	trans	-71.2	135.7	-178.9	0	0	0	0	0	112.1	Y249 A250	Y249-A252 WeakPolarHBondContact O-CB 3.45Å; Y249-A252 PolarHBondContact O-N 2.96Å; A250-A252 PolarHBondContact O-N 2.87Å
253	G	82.5	Confident	84.5	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	7%	0.074	C	C	.	.	T	Hydrogen-bonded Turn	trans	135.1	-11.8	175.2	0	0	0	0	0	114.6	F255 Y256	G253-F255 PolarHBondContact O-N 3.46Å; G253-Y256 WeakPolarHBondContact O-CD2 3.36Å; G253-Y256 PolarHBondContact O-N 3.27Å
254	W	88.3	Confident	84.3	Confident	1 Å²	1	15.5 Å²	15.5	0%	0.004	7%	0.074	C	C	.	.	T	Hydrogen-bonded Turn	trans	-57.5	-21	179.3	48.9	-105.3	0	0	0	114.8	I62 G98 A99 Y102 M279 I405 F436	I62-W254 HydrophobicContact CD1-CB 3.87Å; G98-W254 VanDerWaalsContact C-CH2 3.48Å; G98-W254 WeakPolarHBondContact O-CZ3 3.13Å; A99-W254 HydrophobicContact CB-CB 3.86Å; A99-W254 HydrophobicContact CB-CD2 3.73Å; A99-W254 HydrophobicContact CB-CE3 3.65Å; A99-W254 HydrophobicContact CB-CG 3.82Å; A99-W254 HydrophobicContact CB-CZ3 4.41Å; Y102-W254 HydrophobicContact CD1-CZ3 4.04Å; Y102-W254 AromaticContact CD2-CH2 3.54Å; Y102-W254 HydrophobicContact CD2-CH2 3.54Å; Y102-W254 AromaticContact CD2-CZ3 3.28Å; Y102-W254 HydrophobicContact CD2-CZ3 3.28Å; Y102-W254 HydrophobicContact CE1-CZ3 4.43Å; Y102-W254 AromaticContact CE2-CH2 3.55Å; Y102-W254 HydrophobicContact CE2-CH2 3.55Å; Y102-W254 AromaticContact CE2-CZ3 3.72Å; Y102-W254 HydrophobicContact CE2-CZ3 3.72Å; Y102-W254 HydrophobicContact CG-CE3 4.41Å; Y102-W254 HydrophobicContact CG-CH2 4.16Å; Y102-W254 AromaticContact CG-CZ3 3.44Å; Y102-W254 HydrophobicContact CG-CZ3 3.44Å; Y102-W254 VanDerWaalsContact CG-CZ3 3.44Å; W254-M279 HydrophobicContact CB-SD 3.63Å; W254-M279 HydrophobicContact CG-SD 4.13Å; W254-I405 HydrophobicContact CH2-CG2 4.36Å; W254-F436 HydrophobicContact CH2-CE1 4.3Å; W254-F436 HydrophobicContact CH2-CZ 4.2Å; W254-F436 HydrophobicContact CZ2-CE1 4.31Å; W254-F436 AromaticContact CZ2-CZ 3.75Å; W254-F436 HydrophobicContact CZ2-CZ 3.75Å
255	F	86.8	Confident	84.2	Confident	12 Å²	12	17 Å²	17	5%	0.053	9%	0.085	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.7	-5.1	178.2	50.3	-105.5	0	0	0	114.2	Y102 H115 G253 L257 N258 F259 I405	Y102-F255 HydrophobicContact CD1-CB 3.79Å; Y102-F255 HydrophobicContact CE1-CB 3.89Å; Y102-F255 HydrophobicContact CG-CB 4.46Å; H115-F255 AromaticContact CE1-CG 3.77Å; H115-F255 AromaticContact NE2-CD2 3.5Å; H115-F255 WeakPolarHBondContact NE2-CD2 3.48Å; H115-F255 AromaticContact NE2-CE2 3.71Å; H115-F255 AromaticContact NE2-CG 3.74Å; G253-F255 PolarHBondContact O-N 3.46Å; F255-L257 VanDerWaalsContact C-N 3.29Å; F255-L257 PolarHBondContact O-N 3.25Å; F255-N258 VanDerWaalsContact O-CB 3.29Å; F255-N258 WeakPolarHBondContact O-CB 3.47Å; F255-N258 PolarHBondContact O-N 3Å; F255-N258 VanDerWaalsContact O-N 3.1Å; F255-F259 AromaticContact CD2-CE2 3.88Å; F255-F259 HydrophobicContact CD2-CE2 3.88Å; F255-F259 HydrophobicContact CE2-CE2 4.43Å; F255-I405 HydrophobicContact CD1-CD1 4.34Å; F255-I405 HydrophobicContact CE1-CD1 3.97Å
256	Y	81.3	Confident	84.4	Confident	57 Å²	57	19.4 Å²	19.4	22%	0.224	10%	0.099	C	C	.	.	G	3₁₀ helix	trans	-64.4	-31.4	-174.7	-85.7	-68.5	0	0	0	113.6	T61 R140 G253 N258 F259 A342	T61-Y256 HydrophobicContact CG2-CD2 4.07Å; T61-Y256 HydrophobicContact CG2-CG 4.33Å; R140-Y256 PolarHBondContact NH1-OH 3.35Å; G253-Y256 WeakPolarHBondContact O-CD2 3.36Å; G253-Y256 PolarHBondContact O-N 3.27Å; Y256-N258 PolarHBondContact O-N 3.39Å; Y256-F259 HydrophobicContact CD1-CD2 4.42Å; Y256-F259 WeakPolarHBondContact O-CB 3.39Å; Y256-F259 PolarHBondContact O-N 3.33Å; Y256-F259 VanDerWaalsContact O-N 3.08Å; Y256-A342 HydrophobicContact CE1-CB 4.01Å
257	L	82.6	Confident	84.4	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	10%	0.097	C	C	.	.	G	3₁₀ helix	trans	-63.2	-28.3	176.2	-168.8	65.2	0	0	0	112.1	V49 I58 F255 F259 V260 T261 V264 V271 A274	V49-L257 HydrophobicContact CG1-CD1 4.1Å; I58-L257 HydrophobicContact CD1-CB 3.91Å; I58-L257 HydrophobicContact CD1-CD2 3.8Å; I58-L257 HydrophobicContact CD1-CG 4.44Å; I58-L257 HydrophobicContact CG1-CB 3.98Å; F255-L257 VanDerWaalsContact C-N 3.29Å; F255-L257 PolarHBondContact O-N 3.25Å; L257-F259 PolarHBondContact O-N 2.95Å; L257-V260 HydrophobicContact CD1-CG2 4.21Å; L257-V260 WeakPolarHBondContact O-CG2 3.36Å; L257-V260 PolarHBondContact O-N 3.24Å; L257-T261 PolarHBondContact O-N 3.09Å; L257-T261 PolarHBondContact O-OG1 3.12Å; L257-V264 HydrophobicContact CD1-CG2 3.91Å; L257-V264 HydrophobicContact CG-CG2 4.3Å; L257-V271 HydrophobicContact CD2-CG1 4.47Å; L257-V271 HydrophobicContact CD2-CG2 4.29Å; L257-A274 HydrophobicContact CD2-CB 3.74Å
258	N	85.3	Confident	84.4	Confident	0 Å²	0	22.9 Å²	22.9	0%	0	11%	0.114	C	C	.	.	G	3₁₀ helix	trans	-69.2	-17.2	176.7	-67.8	87.5	0	0	0	113.6	Y102 G114 Y118 F255 Y256 T261	Y102-N258 HydrophobicContact CD1-CB 4.38Å; Y102-N258 PolarHBondContact O-ND2 3.33Å; G114-N258 PolarHBondContact N-O 2.82Å; Y118-N258 HydrophobicContact CE2-CB 4.14Å; Y118-N258 WeakPolarHBondContact OH-CB 3.13Å; Y118-N258 PolarHBondContact OH-ND2 3.35Å; F255-N258 VanDerWaalsContact O-CB 3.29Å; F255-N258 WeakPolarHBondContact O-CB 3.47Å; F255-N258 PolarHBondContact O-N 3Å; F255-N258 VanDerWaalsContact O-N 3.1Å; Y256-N258 PolarHBondContact O-N 3.39Å; N258-T261 VanDerWaalsContact CA-OG1 3.23Å; N258-T261 WeakPolarHBondContact CA-OG1 3.18Å; N258-T261 PolarHBondContact O-OG1 3.44Å
259	F	78	Confident	84.5	Confident	17 Å²	17	30.2 Å²	30.2	8%	0.075	15%	0.146	C	C	.	.	G	3₁₀ helix	trans	-78.9	-23.7	175.1	-77.6	-91.8	0	0	0	113.1	S112 G113 H115 F255 Y256 L257 M346	S112-F259 WeakPolarHBondContact CB-O 3.34Å; G113-F259 PolarHBondContact N-O 3.31Å; G113-F259 VanDerWaalsContact O-CE1 3.28Å; G113-F259 WeakPolarHBondContact O-CE1 3.39Å; H115-F259 AromaticContact CD2-CE2 3.81Å; H115-F259 AromaticContact CD2-CZ 3.46Å; H115-F259 VanDerWaalsContact CD2-CZ 3.46Å; H115-F259 WeakPolarHBondContact CD2-CZ 3.43Å; H115-F259 AromaticContact NE2-CE2 3.94Å; F255-F259 AromaticContact CD2-CE2 3.88Å; F255-F259 HydrophobicContact CD2-CE2 3.88Å; F255-F259 HydrophobicContact CE2-CE2 4.43Å; Y256-F259 HydrophobicContact CD1-CD2 4.42Å; Y256-F259 WeakPolarHBondContact O-CB 3.39Å; Y256-F259 PolarHBondContact O-N 3.33Å; Y256-F259 VanDerWaalsContact O-N 3.08Å; L257-F259 PolarHBondContact O-N 2.95Å; F259-M346 HydrophobicContact CE1-SD 4.46Å
260	V	76.4	Confident	84.8	Confident	12 Å²	12	29.5 Å²	29.5	7%	0.073	15%	0.145	C	C	.	.	S	Bend	trans	-116.4	25.4	-176.7	-65.6	0	0	0	0	111.8	L257 E262 E263 V264	L257-V260 HydrophobicContact CD1-CG2 4.21Å; L257-V260 WeakPolarHBondContact O-CG2 3.36Å; L257-V260 PolarHBondContact O-N 3.24Å; V260-E262 VanDerWaalsContact C-N 3.26Å; V260-E262 PolarHBondContact O-N 3.38Å; V260-E263 WeakPolarHBondContact O-CB 3.49Å; V260-E263 PolarHBondContact O-N 3.46Å; V260-V264 PolarHBondContact O-N 2.88Å
261	T	80.1	Confident	85	Confident	2 Å²	2	29.4 Å²	29.4	1%	0.012	14%	0.144	C	C	.	.	G	3₁₀ helix	trans	-61.8	-30.2	-174.2	-57	0	0	0	0	113.5	L257 N258 E263 V264 P267 V271	L257-T261 PolarHBondContact O-N 3.09Å; L257-T261 PolarHBondContact O-OG1 3.12Å; N258-T261 VanDerWaalsContact CA-OG1 3.23Å; N258-T261 WeakPolarHBondContact CA-OG1 3.18Å; N258-T261 PolarHBondContact O-OG1 3.44Å; T261-E263 PolarHBondContact O-N 3.36Å; T261-V264 PolarHBondContact O-N 2.85Å; T261-P267 HydrophobicContact CG2-CB 4.01Å; T261-V271 HydrophobicContact CG2-CG2 4.43Å
262	E	79.3	Confident	85.2	Confident	54 Å²	54	29.9 Å²	29.9	25%	0.252	15%	0.147	S	C	.	.	G	3₁₀ helix	trans	-64.1	-27.4	174.3	-68.9	166.3	-180	0	0	112.2	K110 K111 S112 V260 R352	K110-E262 VanDerWaalsContact O-CG 3.29Å; K110-E262 WeakPolarHBondContact O-CG 3.37Å; K111-E262 WeakPolarHBondContact CA-OE1 3.24Å; S112-E262 VanDerWaalsContact CB-CD 3.47Å; S112-E262 VanDerWaalsContact CB-OE2 3.27Å; S112-E262 WeakPolarHBondContact CB-OE2 3.45Å; S112-E262 PolarHBondContact N-OE1 2.88Å; S112-E262 VanDerWaalsContact OG-CB 3.22Å; S112-E262 WeakPolarHBondContact OG-CB 3.35Å; S112-E262 WeakPolarHBondContact OG-CG 3.45Å; S112-E262 PolarHBondContact OG-OE2 3.37Å; V260-E262 VanDerWaalsContact C-N 3.26Å; V260-E262 PolarHBondContact O-N 3.38Å; E262-R352 IonicContact OE1-NH2 2.87Å
263	E	82.1	Confident	85.6	Confident	26 Å²	26	32.9 Å²	32.9	12%	0.121	16%	0.161	C	C	.	.	G	3₁₀ helix	trans	-88	-7.9	180	-59.8	178.7	-149.8	0	0	113.1	L45 K47 K48 V49 V260 T261	L45-E263 HydrophobicContact CB-CG 4.04Å; K47-E263 CarbonylContact C-O 3.31Å; K47-E263 WeakPolarHBondContact CA-O 3.5Å; K48-E263 PolarHBondContact N-O 3.32Å; V49-E263 HydrophobicContact CG2-CB 4.07Å; V49-E263 PolarHBondContact N-O 3.02Å; V260-E263 WeakPolarHBondContact O-CB 3.49Å; V260-E263 PolarHBondContact O-N 3.46Å; T261-E263 PolarHBondContact O-N 3.36Å
264	V	85.9	Confident	86.1	Confident	1 Å²	1	32.9 Å²	32.9	1%	0.006	16%	0.161	C	C	.	.	B	Isolated β-bridge	trans	-78.6	128.6	-178.1	178.3	0	0	0	0	110.6	V49 L257 V260 T261 N266 P267 T270 V271	V49-V264 HydrophobicContact CB-CG2 4.14Å; V49-V264 HydrophobicContact CG1-CG2 4.19Å; L257-V264 HydrophobicContact CD1-CG2 3.91Å; L257-V264 HydrophobicContact CG-CG2 4.3Å; V260-V264 PolarHBondContact O-N 2.88Å; T261-V264 PolarHBondContact O-N 2.85Å; V264-N266 PolarHBondContact O-N 3.35Å; V264-P267 HydrophobicContact CB-CB 4.42Å; V264-P267 HydrophobicContact CG1-CB 4.35Å; V264-T270 HydrophobicContact CG1-CG2 3.6Å; V264-V271 HydrophobicContact CG1-CG2 4.11Å
265	D	86.9	Confident	86.2	Confident	82 Å²	82	32.9 Å²	32.9	44%	0.439	16%	0.16	S	C	.	.	S	Bend	trans	-72.4	127	171.4	-174.1	29.4	0	0	0	110.2	V49 T270	V49-D265 PolarHBondContact O-N 3.1Å; D265-T270 VanDerWaalsContact O-CB 3.22Å; D265-T270 WeakPolarHBondContact O-CB 3.28Å; D265-T270 PolarHBondContact O-OG1 3.29Å
266	N	88.1	Confident	86.5	Confident	70 Å²	70	34.3 Å²	34.3	37%	0.374	17%	0.172	S	C	.	.	S	Bend	trans	44.6	69.2	-174.7	-166.7	1.9	0	0	0	114.1	V264 E268 K269 T270	V264-N266 PolarHBondContact O-N 3.35Å; N266-E268 PolarHBondContact O-N 2.83Å; N266-E268 VanDerWaalsContact O-N 3.09Å; N266-K269 PolarHBondContact O-N 2.87Å; N266-T270 VanDerWaalsContact O-CB 3.32Å; N266-T270 WeakPolarHBondContact O-CB 3.21Å; N266-T270 PolarHBondContact O-N 2.84Å; N266-T270 PolarHBondContact O-OG1 3.2Å; N266-T270 VanDerWaalsContact O-OG1 3.1Å
267	P	87.2	Confident	87.1	Confident	18 Å²	18	34.6 Å²	34.6	12%	0.117	18%	0.177	C	C	.	.	H	α-helix	trans	-60.1	-28.5	-170.6	23.5	-33.6	0	0	0	113.5	K110 T261 V264 K269 V271	K110-P267 HydrophobicContact CD-CG 4.37Å; T261-P267 HydrophobicContact CG2-CB 4.01Å; V264-P267 HydrophobicContact CB-CB 4.42Å; V264-P267 HydrophobicContact CG1-CB 4.35Å; P267-K269 VanDerWaalsContact C-N 3.29Å; P267-K269 PolarHBondContact O-N 3.45Å; P267-V271 HydrophobicContact CB-CG2 4.07Å; P267-V271 VanDerWaalsContact O-CB 3.26Å; P267-V271 WeakPolarHBondContact O-CB 3.34Å; P267-V271 WeakPolarHBondContact O-CG2 3.35Å; P267-V271 PolarHBondContact O-N 3.29Å
268	E	89.9	Confident	87.6	Confident	76 Å²	76	34.6 Å²	34.6	36%	0.355	18%	0.177	S	C	.	.	H	α-helix	trans	-61.4	-34.8	-179	-61.1	-176.2	-175	0	0	113.4	K110 N266 P272 P425	K110-E268 IonicContact NZ-OE1 2.98Å; K110-E268 PolarHBondContact NZ-OE1 3.4Å; N266-E268 PolarHBondContact O-N 2.83Å; N266-E268 VanDerWaalsContact O-N 3.09Å; E268-P272 WeakPolarHBondContact O-CD 3.26Å; E268-P272 WeakPolarHBondContact O-CG 3.18Å; E268-P425 HydrophobicContact CB-CB 3.95Å; E268-P425 HydrophobicContact CB-CG 4.49Å; E268-P425 HydrophobicContact CG-CB 3.81Å; E268-P425 HydrophobicContact CG-CG 3.79Å
269	K	90.1	Very high	87.9	Confident	154 Å²	154	34.7 Å²	34.7	67%	0.67	18%	0.177	S	C	*	.	H	α-helix	trans	-101.5	-40.6	178	-64	-173.8	-179.1	-179.8	0	111.6	N266 P267 L273	N266-K269 PolarHBondContact O-N 2.87Å; P267-K269 VanDerWaalsContact C-N 3.29Å; P267-K269 PolarHBondContact O-N 3.45Å; K269-L273 VanDerWaalsContact O-CB 3.25Å; K269-L273 WeakPolarHBondContact O-CB 3.3Å; K269-L273 PolarHBondContact O-N 2.86Å
270	T	91.1	Very high	88.7	Confident	16 Å²	16	36.6 Å²	36.6	10%	0.098	20%	0.196	C	C	.	.	H	α-helix	trans	-70.6	-41.8	-172.6	-59.7	0	0	0	0	112.2	L51 V264 D265 N266 A274	L51-T270 HydrophobicContact CB-CG2 4.14Å; L51-T270 HydrophobicContact CD1-CG2 4.19Å; V264-T270 HydrophobicContact CG1-CG2 3.6Å; D265-T270 VanDerWaalsContact O-CB 3.22Å; D265-T270 WeakPolarHBondContact O-CB 3.28Å; D265-T270 PolarHBondContact O-OG1 3.29Å; N266-T270 VanDerWaalsContact O-CB 3.32Å; N266-T270 WeakPolarHBondContact O-CB 3.21Å; N266-T270 PolarHBondContact O-N 2.84Å; N266-T270 PolarHBondContact O-OG1 3.2Å; N266-T270 VanDerWaalsContact O-OG1 3.1Å; T270-A274 WeakPolarHBondContact O-CB 3.28Å; T270-A274 PolarHBondContact O-N 3.49Å
271	V	91.1	Very high	89.4	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-65.3	-52.3	-177.1	174.6	0	0	0	0	111.8	A103 L257 T261 V264 P267 L273 A274 I275	A103-V271 HydrophobicContact CB-CG1 4.39Å; L257-V271 HydrophobicContact CD2-CG1 4.47Å; L257-V271 HydrophobicContact CD2-CG2 4.29Å; T261-V271 HydrophobicContact CG2-CG2 4.43Å; V264-V271 HydrophobicContact CG1-CG2 4.11Å; P267-V271 HydrophobicContact CB-CG2 4.07Å; P267-V271 VanDerWaalsContact O-CB 3.26Å; P267-V271 WeakPolarHBondContact O-CB 3.34Å; P267-V271 WeakPolarHBondContact O-CG2 3.35Å; P267-V271 PolarHBondContact O-N 3.29Å; V271-L273 VanDerWaalsContact C-N 3.33Å; V271-L273 PolarHBondContact O-N 3.02Å; V271-A274 PolarHBondContact O-N 3.45Å; V271-I275 HydrophobicContact CG1-CD1 3.69Å; V271-I275 WeakPolarHBondContact O-CB 3.41Å; V271-I275 WeakPolarHBondContact O-CG1 3.48Å; V271-I275 PolarHBondContact O-N 3.37Å; V271-I275 VanDerWaalsContact O-N 3.07Å
272	P	92.4	Very high	89.9	Confident	10 Å²	10	39.1 Å²	39.1	7%	0.065	21%	0.208	C	C	.	.	H	α-helix	trans	-62.9	-39.1	179.9	-21.6	33.3	0	0	0	113.1	A103 T107 E268 S276 F426	A103-P272 HydrophobicContact CB-CB 4.21Å; A103-P272 HydrophobicContact CB-CG 4.25Å; T107-P272 HydrophobicContact CG2-CG 3.89Å; E268-P272 WeakPolarHBondContact O-CD 3.26Å; E268-P272 WeakPolarHBondContact O-CG 3.18Å; P272-S276 WeakPolarHBondContact O-CB 3.35Å; P272-S276 PolarHBondContact O-N 2.85Å; P272-S276 PolarHBondContact O-OG 3.44Å; P272-F426 HydrophobicContact CB-CD1 4.29Å; P272-F426 HydrophobicContact CB-CD2 3.74Å; P272-F426 HydrophobicContact CB-CE1 4.34Å; P272-F426 HydrophobicContact CB-CE2 3.8Å; P272-F426 HydrophobicContact CB-CG 3.99Å; P272-F426 HydrophobicContact CB-CZ 4.11Å; P272-F426 HydrophobicContact CG-CB 3.89Å; P272-F426 HydrophobicContact CG-CD1 4.09Å; P272-F426 HydrophobicContact CG-CD2 3.79Å; P272-F426 HydrophobicContact CG-CE2 4.35Å; P272-F426 HydrophobicContact CG-CG 3.64Å
273	L	92.9	Very high	90.6	Very high	83 Å²	83	37.6 Å²	37.6	44%	0.435	20%	0.203	S	C	.	.	H	α-helix	trans	-70.6	-46	-179	-171.4	64.6	0	0	0	111.6	L51 K269 V271 I275 S276 I277	L51-L273 HydrophobicContact CD1-CB 3.96Å; L51-L273 HydrophobicContact CD1-CD2 3.88Å; L51-L273 HydrophobicContact CD1-CG 3.93Å; L51-L273 HydrophobicContact CD2-CD2 3.5Å; L51-L273 VanDerWaalsContact CD2-CD2 3.5Å; L51-L273 HydrophobicContact CD2-CG 4.29Å; L51-L273 HydrophobicContact CG-CD2 4.35Å; K269-L273 VanDerWaalsContact O-CB 3.25Å; K269-L273 WeakPolarHBondContact O-CB 3.3Å; K269-L273 PolarHBondContact O-N 2.86Å; V271-L273 VanDerWaalsContact C-N 3.33Å; V271-L273 PolarHBondContact O-N 3.02Å; L273-I275 VanDerWaalsContact C-N 3.34Å; L273-I275 PolarHBondContact O-N 3.41Å; L273-S276 PolarHBondContact O-N 3.41Å; L273-I277 HydrophobicContact CD1-CD1 3.73Å; L273-I277 HydrophobicContact CD1-CG1 4.2Å; L273-I277 HydrophobicContact CG-CD1 3.74Å; L273-I277 HydrophobicContact CG-CG1 4.47Å; L273-I277 WeakPolarHBondContact O-CB 3.27Å; L273-I277 VanDerWaalsContact O-CG1 3.29Å; L273-I277 WeakPolarHBondContact O-CG1 3.29Å; L273-I277 PolarHBondContact O-N 3.39Å
274	A	91.8	Very high	91	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-58	-48.8	176.8	0	0	0	0	0	110.8	L51 I55 I58 L257 T270 V271 S278	L51-A274 HydrophobicContact CD1-CB 3.96Å; I55-A274 HydrophobicContact CG1-CB 4.12Å; I58-A274 HydrophobicContact CD1-CB 4.2Å; L257-A274 HydrophobicContact CD2-CB 3.74Å; T270-A274 WeakPolarHBondContact O-CB 3.28Å; T270-A274 PolarHBondContact O-N 3.49Å; V271-A274 PolarHBondContact O-N 3.45Å; A274-S278 VanDerWaalsContact O-CB 3.23Å; A274-S278 WeakPolarHBondContact O-CB 2.96Å; A274-S278 PolarHBondContact O-N 3.3Å; A274-S278 PolarHBondContact O-OG 3.25Å
275	I	92.1	Very high	91.1	Very high	0 Å²	0	40.3 Å²	40.3	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-60	-49.6	179.8	-74.9	171.8	0	0	0	111.6	I58 A99 A103 V271 L273 S278 M279	I58-I275 HydrophobicContact CD1-CB 4.39Å; I58-I275 HydrophobicContact CD1-CG1 3.64Å; A99-I275 HydrophobicContact CB-CG2 3.26Å; A103-I275 HydrophobicContact CB-CD1 3.98Å; V271-I275 HydrophobicContact CG1-CD1 3.69Å; V271-I275 WeakPolarHBondContact O-CB 3.41Å; V271-I275 WeakPolarHBondContact O-CG1 3.48Å; V271-I275 PolarHBondContact O-N 3.37Å; V271-I275 VanDerWaalsContact O-N 3.07Å; L273-I275 VanDerWaalsContact C-N 3.34Å; L273-I275 PolarHBondContact O-N 3.41Å; I275-S278 PolarHBondContact O-N 3.31Å; I275-M279 HydrophobicContact CG2-CG 4.48Å; I275-M279 WeakPolarHBondContact O-CB 3.34Å; I275-M279 VanDerWaalsContact O-CG 3.31Å; I275-M279 WeakPolarHBondContact O-CG 3.45Å; I275-M279 PolarHBondContact O-N 3.24Å
276	S	93.1	Very high	91.2	Very high	42 Å²	42	36.4 Å²	36.4	29%	0.294	20%	0.204	S	C	.	.	H	α-helix	trans	-65.3	-45	-175.2	-56.2	0	0	0	0	111.9	P272 L273 M279 A280	P272-S276 WeakPolarHBondContact O-CB 3.35Å; P272-S276 PolarHBondContact O-N 2.85Å; P272-S276 PolarHBondContact O-OG 3.44Å; L273-S276 PolarHBondContact O-N 3.41Å; S276-M279 PolarHBondContact O-N 3.3Å; S276-A280 PolarHBondContact O-N 3.06Å; S276-A280 VanDerWaalsContact O-N 3.16Å
277	I	93.9	Very high	91.4	Very high	63 Å²	63	34.5 Å²	34.5	32%	0.323	19%	0.194	S	C	.	.	H	α-helix	trans	-63.9	-47.2	177.9	-66.1	175.2	0	0	0	110.1	I55 L273 M279 A280 I281	I55-I277 HydrophobicContact CD1-CB 4.26Å; I55-I277 HydrophobicContact CD1-CD1 4.18Å; I55-I277 HydrophobicContact CD1-CG2 3.99Å; I55-I277 HydrophobicContact CG1-CG2 4.48Å; L273-I277 HydrophobicContact CD1-CD1 3.73Å; L273-I277 HydrophobicContact CD1-CG1 4.2Å; L273-I277 HydrophobicContact CG-CD1 3.74Å; L273-I277 HydrophobicContact CG-CG1 4.47Å; L273-I277 WeakPolarHBondContact O-CB 3.27Å; L273-I277 VanDerWaalsContact O-CG1 3.29Å; L273-I277 WeakPolarHBondContact O-CG1 3.29Å; L273-I277 PolarHBondContact O-N 3.39Å; I277-M279 PolarHBondContact O-N 3.28Å; I277-A280 PolarHBondContact O-N 3.41Å; I277-I281 HydrophobicContact CG2-CD1 3.66Å; I277-I281 HydrophobicContact CG2-CG1 4.33Å; I277-I281 WeakPolarHBondContact O-CG1 3.3Å; I277-I281 PolarHBondContact O-N 3.33Å
278	S	91.3	Very high	91.4	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	21%	0.208	C	C	.	.	H	α-helix	trans	-60.5	-42.9	179.5	-67.1	0	0	0	0	112.3	I55 A274 I275 A280 I281 V282	I55-S278 WeakPolarHBondContact CA-OG 3.04Å; I55-S278 PolarHBondContact O-OG 2.82Å; A274-S278 VanDerWaalsContact O-CB 3.23Å; A274-S278 WeakPolarHBondContact O-CB 2.96Å; A274-S278 PolarHBondContact O-N 3.3Å; A274-S278 PolarHBondContact O-OG 3.25Å; I275-S278 PolarHBondContact O-N 3.31Å; S278-A280 VanDerWaalsContact C-N 3.34Å; S278-A280 PolarHBondContact O-N 3.32Å; S278-I281 PolarHBondContact O-N 3.12Å; S278-V282 WeakPolarHBondContact O-CB 3.46Å; S278-V282 VanDerWaalsContact O-CG2 3.24Å; S278-V282 WeakPolarHBondContact O-CG2 3.45Å; S278-V282 PolarHBondContact O-N 2.97Å
279	M	93.5	Very high	91.2	Very high	2 Å²	2	33.9 Å²	33.9	1%	0.01	19%	0.192	C	C	.	.	H	α-helix	trans	-64	-38.3	178.3	-73.3	-52.4	-54.5	0	0	112.8	I62 S95 L96 A99 Y251 W254 I275 S276 I277 T283	I62-M279 HydrophobicContact CD1-SD 3.83Å; S95-M279 VanDerWaalsContact CB-CE 3.4Å; L96-M279 HydrophobicContact CB-CB 4.46Å; L96-M279 HydrophobicContact CD1-CB 3.9Å; L96-M279 HydrophobicContact CD1-CG 4.17Å; A99-M279 HydrophobicContact CB-CG 4.08Å; Y251-M279 HydrophobicContact CD1-CE 3.95Å; W254-M279 HydrophobicContact CB-SD 3.63Å; W254-M279 HydrophobicContact CG-SD 4.13Å; I275-M279 HydrophobicContact CG2-CG 4.48Å; I275-M279 WeakPolarHBondContact O-CB 3.34Å; I275-M279 VanDerWaalsContact O-CG 3.31Å; I275-M279 WeakPolarHBondContact O-CG 3.45Å; I275-M279 PolarHBondContact O-N 3.24Å; S276-M279 PolarHBondContact O-N 3.3Å; I277-M279 PolarHBondContact O-N 3.28Å; M279-T283 WeakPolarHBondContact O-CB 3.34Å; M279-T283 PolarHBondContact O-N 3.3Å; M279-T283 PolarHBondContact O-OG1 2.88Å
280	A	93.9	Very high	91.1	Very high	57 Å²	57	26.5 Å²	26.5	47%	0.471	16%	0.16	S	C	.	.	H	α-helix	trans	-65.5	-44.2	175.1	0	0	0	0	0	111.9	S276 I277 S278 S284	S276-A280 PolarHBondContact O-N 3.06Å; S276-A280 VanDerWaalsContact O-N 3.16Å; I277-A280 PolarHBondContact O-N 3.41Å; S278-A280 VanDerWaalsContact C-N 3.34Å; S278-A280 PolarHBondContact O-N 3.32Å; A280-S284 WeakPolarHBondContact O-CB 3.42Å; A280-S284 PolarHBondContact O-N 3.42Å; A280-S284 PolarHBondContact O-OG 2.67Å
281	I	90.4	Very high	91	Very high	67 Å²	67	27 Å²	27	34%	0.344	16%	0.163	S	C	.	.	H	α-helix	trans	-60.2	-52.8	176.3	-68.7	168.8	0	0	0	110.1	I55 V59 I277 S278 T283 S284 C285	I55-I281 HydrophobicContact CG2-CD1 4.3Å; V59-I281 HydrophobicContact CG2-CG2 4.33Å; I277-I281 HydrophobicContact CG2-CD1 3.66Å; I277-I281 HydrophobicContact CG2-CG1 4.33Å; I277-I281 WeakPolarHBondContact O-CG1 3.3Å; I277-I281 PolarHBondContact O-N 3.33Å; S278-I281 PolarHBondContact O-N 3.12Å; I281-T283 VanDerWaalsContact C-N 3.34Å; I281-T283 PolarHBondContact O-N 2.66Å; I281-S284 PolarHBondContact O-N 3.46Å; I281-C285 WeakPolarHBondContact O-CB 3.45Å; I281-C285 PolarHBondContact O-N 3.28Å; I281-C285 PolarHBondContact O-SG 3.13Å
282	V	90.7	Very high	90.7	Very high	0 Å²	0	27 Å²	27	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-60.7	-44.4	-177.9	172.6	0	0	0	0	111.1	V59 I62 I63 Y251 S278 S284 C285 Y286	V59-V282 HydrophobicContact CG2-CG2 4.37Å; I62-V282 HydrophobicContact CB-CG1 4.45Å; I62-V282 HydrophobicContact CB-CG2 4.23Å; I62-V282 HydrophobicContact CD1-CG2 4.22Å; I62-V282 HydrophobicContact CG2-CG1 3.64Å; I62-V282 HydrophobicContact CG2-CG2 4.29Å; I63-V282 HydrophobicContact CD1-CG2 4.25Å; I63-V282 HydrophobicContact CG1-CG1 4.5Å; I63-V282 HydrophobicContact CG1-CG2 3.98Å; Y251-V282 HydrophobicContact CD1-CG1 3.88Å; Y251-V282 HydrophobicContact CE1-CG1 3.84Å; S278-V282 WeakPolarHBondContact O-CB 3.46Å; S278-V282 VanDerWaalsContact O-CG2 3.24Å; S278-V282 WeakPolarHBondContact O-CG2 3.45Å; S278-V282 PolarHBondContact O-N 2.97Å; V282-S284 VanDerWaalsContact C-N 3.34Å; V282-S284 PolarHBondContact O-N 3.02Å; V282-C285 PolarHBondContact O-N 2.88Å; V282-Y286 HydrophobicContact CG1-CD1 4.28Å; V282-Y286 HydrophobicContact CG1-CD2 3.93Å; V282-Y286 HydrophobicContact CG1-CE1 4.05Å; V282-Y286 HydrophobicContact CG1-CE2 3.67Å; V282-Y286 HydrophobicContact CG1-CG 4.25Å; V282-Y286 WeakPolarHBondContact O-CB 3.31Å; V282-Y286 PolarHBondContact O-N 3.41Å
283	T	93.4	Very high	90.4	Very high	23 Å²	23	26.6 Å²	26.6	14%	0.141	16%	0.16	C	C	.	.	H	α-helix	trans	-61.7	-44.9	179.5	-55.3	0	0	0	0	111.3	Y251 M279 I281 Y286 V287	Y251-T283 WeakPolarHBondContact CE1-OG1 3.22Å; M279-T283 WeakPolarHBondContact O-CB 3.34Å; M279-T283 PolarHBondContact O-N 3.3Å; M279-T283 PolarHBondContact O-OG1 2.88Å; I281-T283 VanDerWaalsContact C-N 3.34Å; I281-T283 PolarHBondContact O-N 2.66Å; T283-Y286 PolarHBondContact O-N 3.34Å; T283-V287 WeakPolarHBondContact O-CG2 3.3Å; T283-V287 PolarHBondContact O-N 3.1Å
284	S	90.9	Very high	90.2	Very high	66 Å²	66	22.7 Å²	22.7	46%	0.462	14%	0.139	S	C	.	.	H	α-helix	trans	-61.8	-47.4	176.8	-54.7	0	0	0	0	111.2	A280 I281 V282 Y286 V287 L288	A280-S284 WeakPolarHBondContact O-CB 3.42Å; A280-S284 PolarHBondContact O-N 3.42Å; A280-S284 PolarHBondContact O-OG 2.67Å; I281-S284 PolarHBondContact O-N 3.46Å; V282-S284 VanDerWaalsContact C-N 3.34Å; V282-S284 PolarHBondContact O-N 3.02Å; S284-Y286 PolarHBondContact O-N 3.3Å; S284-V287 PolarHBondContact O-N 3.42Å; S284-L288 WeakPolarHBondContact O-CB 3.38Å; S284-L288 WeakPolarHBondContact O-CD1 3.48Å; S284-L288 WeakPolarHBondContact O-CG 3.31Å; S284-L288 PolarHBondContact O-N 3.29Å
285	C	87.7	Confident	89.9	Confident	17 Å²	17	23.1 Å²	23.1	12%	0.115	14%	0.142	C	C	.	.	H	α-helix	trans	-59.2	-46.5	177.3	-71.2	0	0	0	0	111.9	I207 I281 V282 L288 T289	I207-C285 HydrophobicContact CG2-CB 4.26Å; I281-C285 WeakPolarHBondContact O-CB 3.45Å; I281-C285 PolarHBondContact O-N 3.28Å; I281-C285 PolarHBondContact O-SG 3.13Å; V282-C285 PolarHBondContact O-N 2.88Å; C285-L288 PolarHBondContact O-N 3.16Å; C285-T289 WeakPolarHBondContact O-CB 3.43Å; C285-T289 PolarHBondContact O-N 3.26Å; C285-T289 PolarHBondContact O-OG1 2.89Å
286	Y	90.4	Very high	89.5	Confident	1 Å²	1	24.4 Å²	24.4	0%	0.004	15%	0.15	C	C	.	.	H	α-helix	trans	-65.7	-43.5	-178.4	-74.8	0.6	0	0	0	112.7	I62 I63 I67 W88 A250 Y251 V282 T283 S284 T289 N290	I62-Y286 HydrophobicContact CG2-CE2 4.5Å; I62-Y286 PolarHBondContact O-OH 2.86Å; I63-Y286 HydrophobicContact CG1-CE1 4.15Å; I67-Y286 HydrophobicContact CB-CD1 4.22Å; I67-Y286 HydrophobicContact CB-CE1 3.82Å; I67-Y286 HydrophobicContact CD1-CD1 3.61Å; I67-Y286 HydrophobicContact CD1-CD2 4.39Å; I67-Y286 HydrophobicContact CD1-CE1 4.08Å; I67-Y286 HydrophobicContact CD1-CG 3.77Å; I67-Y286 HydrophobicContact CG1-CD1 3.86Å; I67-Y286 HydrophobicContact CG1-CE1 3.99Å; W88-Y286 AromaticContact CE3-CD2 3.84Å; W88-Y286 HydrophobicContact CE3-CD2 3.84Å; W88-Y286 HydrophobicContact CE3-CG 4.27Å; W88-Y286 HydrophobicContact CH2-CD2 4.28Å; W88-Y286 AromaticContact CZ3-CD2 3.33Å; W88-Y286 HydrophobicContact CZ3-CD2 3.33Å; W88-Y286 AromaticContact CZ3-CE2 3.96Å; W88-Y286 HydrophobicContact CZ3-CE2 3.96Å; W88-Y286 AromaticContact CZ3-CG 3.92Å; W88-Y286 HydrophobicContact CZ3-CG 3.92Å; A250-Y286 HydrophobicContact CB-CE2 3.91Å; A250-Y286 PolarHBondContact O-OH 2.89Å; A250-Y286 VanDerWaalsContact O-OH 3.09Å; Y251-Y286 HydrophobicContact CD1-CD2 4.05Å; Y251-Y286 HydrophobicContact CD1-CE2 4.05Å; Y251-Y286 HydrophobicContact CD2-CD2 4.3Å; Y251-Y286 HydrophobicContact CD2-CE2 4.44Å; Y251-Y286 AromaticContact CE1-CD2 3.58Å; Y251-Y286 HydrophobicContact CE1-CD2 3.58Å; Y251-Y286 HydrophobicContact CE1-CE2 4.05Å; Y251-Y286 HydrophobicContact CE1-CG 4.47Å; Y251-Y286 AromaticContact CE2-CD2 3.87Å; Y251-Y286 HydrophobicContact CE2-CD2 3.87Å; Y251-Y286 HydrophobicContact CE2-CE2 4.45Å; Y251-Y286 HydrophobicContact CG-CD2 4.39Å; Y251-Y286 HydrophobicContact CG-CE2 4.25Å; Y251-Y286 AromaticContact CZ-CD2 3.46Å; Y251-Y286 VanDerWaalsContact CZ-CD2 3.46Å; V282-Y286 HydrophobicContact CG1-CD1 4.28Å; V282-Y286 HydrophobicContact CG1-CD2 3.93Å; V282-Y286 HydrophobicContact CG1-CE1 4.05Å; V282-Y286 HydrophobicContact CG1-CE2 3.67Å; V282-Y286 HydrophobicContact CG1-CG 4.25Å; V282-Y286 WeakPolarHBondContact O-CB 3.31Å; V282-Y286 PolarHBondContact O-N 3.41Å; T283-Y286 PolarHBondContact O-N 3.34Å; S284-Y286 PolarHBondContact O-N 3.3Å; Y286-T289 PolarHBondContact O-N 2.79Å; Y286-N290 PolarHBondContact O-N 3.49Å; Y286-N290 PolarHBondContact O-ND2 3.23Å
287	V	91.3	Very high	89.2	Confident	29 Å²	29	22.4 Å²	22.4	18%	0.176	14%	0.136	C	C	.	.	H	α-helix	trans	-61.7	-47.6	176	173.2	0	0	0	0	110.1	W88 I89 T283 S284 T289 N290 V291	W88-V287 HydrophobicContact CB-CG2 4.17Å; I89-V287 HydrophobicContact CG1-CG2 3.64Å; T283-V287 WeakPolarHBondContact O-CG2 3.3Å; T283-V287 PolarHBondContact O-N 3.1Å; S284-V287 PolarHBondContact O-N 3.42Å; V287-T289 VanDerWaalsContact C-N 3.35Å; V287-T289 PolarHBondContact O-N 3.4Å; V287-N290 PolarHBondContact O-N 2.65Å; V287-N290 VanDerWaalsContact O-N 3.17Å; V287-V291 WeakPolarHBondContact O-CG2 3.24Å; V287-V291 PolarHBondContact O-N 2.96Å
288	L	87.6	Confident	88.9	Confident	78 Å²	78	21.5 Å²	21.5	41%	0.408	14%	0.135	S	C	.	.	H	α-helix	trans	-64	-38	179.4	-68.2	169.4	0	0	0	112.3	L211 N214 S284 C285 N290 V291 A292	L211-L288 HydrophobicContact CD2-CB 3.36Å; L211-L288 HydrophobicContact CD2-CD1 3.55Å; L211-L288 HydrophobicContact CD2-CG 4.05Å; N214-L288 PolarHBondContact ND2-O 2.7Å; S284-L288 WeakPolarHBondContact O-CB 3.38Å; S284-L288 WeakPolarHBondContact O-CD1 3.48Å; S284-L288 WeakPolarHBondContact O-CG 3.31Å; S284-L288 PolarHBondContact O-N 3.29Å; C285-L288 PolarHBondContact O-N 3.16Å; L288-N290 VanDerWaalsContact C-N 3.35Å; L288-V291 PolarHBondContact O-N 3.03Å; L288-A292 PolarHBondContact O-N 3.37Å
289	T	85.6	Confident	88.7	Confident	3 Å²	3	23.1 Å²	23.1	2%	0.018	15%	0.148	C	C	.	.	H	α-helix	trans	-64.2	-38.3	174	-63.7	0	0	0	0	111.9	I67 L210 C285 Y286 V287 A292 Y293	I67-T289 HydrophobicContact CD1-CG2 4.39Å; I67-T289 HydrophobicContact CG1-CG2 3.99Å; L210-T289 HydrophobicContact CD1-CG2 4.3Å; C285-T289 WeakPolarHBondContact O-CB 3.43Å; C285-T289 PolarHBondContact O-N 3.26Å; C285-T289 PolarHBondContact O-OG1 2.89Å; Y286-T289 PolarHBondContact O-N 2.79Å; V287-T289 VanDerWaalsContact C-N 3.35Å; V287-T289 PolarHBondContact O-N 3.4Å; T289-A292 WeakPolarHBondContact O-CA 3.4Å; T289-A292 WeakPolarHBondContact O-CB 3.41Å; T289-A292 PolarHBondContact O-N 3.08Å; T289-Y293 HydrophobicContact CG2-CD2 4.34Å; T289-Y293 HydrophobicContact CG2-CE1 4.28Å; T289-Y293 HydrophobicContact CG2-CE2 3.66Å; T289-Y293 PolarHBondContact O-N 2.91Å; T289-Y293 VanDerWaalsContact O-N 3.14Å
290	N	88.9	Confident	88.4	Confident	0 Å²	0	30.7 Å²	30.7	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-71.7	-35.9	176.1	-77.2	-91.9	0	0	0	111.8	P71 L85 W88 Y286 V287 L288 A292 Y293 Y294	P71-N290 WeakPolarHBondContact CB-OD1 3.29Å; L85-N290 HydrophobicContact CD2-CB 3.68Å; W88-N290 WeakPolarHBondContact CZ2-ND2 3.48Å; W88-N290 PolarHBondContact NE1-ND2 2.93Å; W88-N290 VanDerWaalsContact NE1-ND2 3.16Å; W88-N290 PolarHBondContact NE1-OD1 3.38Å; Y286-N290 PolarHBondContact O-N 3.49Å; Y286-N290 PolarHBondContact O-ND2 3.23Å; V287-N290 PolarHBondContact O-N 2.65Å; V287-N290 VanDerWaalsContact O-N 3.17Å; L288-N290 VanDerWaalsContact C-N 3.35Å; N290-A292 PolarHBondContact O-N 3.15Å; N290-Y293 PolarHBondContact O-N 3.44Å; N290-Y293 VanDerWaalsContact O-N 3.15Å; N290-Y294 HydrophobicContact CB-CE2 4.18Å; N290-Y294 WeakPolarHBondContact O-CD2 3.24Å; N290-Y294 PolarHBondContact O-N 2.85Å
291	V	88.3	Confident	88.1	Confident	25 Å²	25	30 Å²	30	15%	0.152	17%	0.171	C	C	.	.	H	α-helix	trans	-57.1	-40	168.8	173.2	0	0	0	0	110.3	L85 L218 F226 V287 L288 Y293 Y294 T295	L85-V291 HydrophobicContact CD1-CG2 4.16Å; L85-V291 HydrophobicContact CD2-CG2 4.13Å; L218-V291 HydrophobicContact CD1-CG1 4.32Å; F226-V291 HydrophobicContact CZ-CG1 3.99Å; V287-V291 WeakPolarHBondContact O-CG2 3.24Å; V287-V291 PolarHBondContact O-N 2.96Å; L288-V291 PolarHBondContact O-N 3.03Å; V291-Y293 PolarHBondContact O-N 2.75Å; V291-Y294 PolarHBondContact O-N 3.41Å; V291-T295 HydrophobicContact CG1-CG2 4.41Å; V291-T295 WeakPolarHBondContact O-CG2 3.45Å; V291-T295 PolarHBondContact O-N 3.39Å
292	A	85	Confident	88	Confident	0 Å²	0	26.8 Å²	26.8	0%	0	15%	0.154	C	C	.	.	H	α-helix	trans	-50.3	-56.7	170.7	0	0	0	0	0	112.3	N214 L288 T289 N290 Y294 T295 V296 F312	N214-A292 WeakPolarHBondContact ND2-CB 3.37Å; N214-A292 WeakPolarHBondContact OD1-CA 3.49Å; N214-A292 WeakPolarHBondContact OD1-CB 3.23Å; L288-A292 PolarHBondContact O-N 3.37Å; T289-A292 WeakPolarHBondContact O-CA 3.4Å; T289-A292 WeakPolarHBondContact O-CB 3.41Å; T289-A292 PolarHBondContact O-N 3.08Å; N290-A292 PolarHBondContact O-N 3.15Å; A292-Y294 PolarHBondContact O-N 2.98Å; A292-T295 PolarHBondContact O-N 2.61Å; A292-T295 PolarHBondContact O-OG1 3.03Å; A292-V296 PolarHBondContact O-N 3.16Å; A292-F312 HydrophobicContact CB-CE2 3.98Å; A292-F312 HydrophobicContact CB-CZ 4.11Å
293	Y	86.3	Confident	87.9	Confident	2 Å²	2	29.8 Å²	29.8	1%	0.008	17%	0.17	C	C	.	.	H	α-helix	trans	-60.4	-40.6	-173.3	-64.3	-30.5	0	0	0	110.5	P71 T289 N290 V291 V296 M297 V308 F312	P71-Y293 HydrophobicContact CB-CD2 4.34Å; P71-Y293 HydrophobicContact CG-CD2 4.16Å; P71-Y293 HydrophobicContact CG-CE2 3.93Å; T289-Y293 HydrophobicContact CG2-CD2 4.34Å; T289-Y293 HydrophobicContact CG2-CE1 4.28Å; T289-Y293 HydrophobicContact CG2-CE2 3.66Å; T289-Y293 PolarHBondContact O-N 2.91Å; T289-Y293 VanDerWaalsContact O-N 3.14Å; N290-Y293 PolarHBondContact O-N 3.44Å; N290-Y293 VanDerWaalsContact O-N 3.15Å; V291-Y293 PolarHBondContact O-N 2.75Å; Y293-V296 PolarHBondContact O-N 3.11Å; Y293-M297 WeakPolarHBondContact O-CA 3.13Å; Y293-M297 WeakPolarHBondContact O-CB 3.25Å; Y293-M297 PolarHBondContact O-N 3.35Å; Y293-V308 HydrophobicContact CD1-CG1 4.25Å; Y293-V308 HydrophobicContact CD2-CG1 3.93Å; Y293-V308 HydrophobicContact CE1-CG1 4.3Å; Y293-V308 HydrophobicContact CE2-CG1 3.97Å; Y293-V308 HydrophobicContact CG-CG1 4.07Å; Y293-F312 HydrophobicContact CD1-CB 4.1Å; Y293-F312 AromaticContact CD1-CD2 3.57Å; Y293-F312 HydrophobicContact CD1-CD2 3.57Å; Y293-F312 HydrophobicContact CD1-CE2 4.07Å; Y293-F312 AromaticContact CD1-CG 3.86Å; Y293-F312 HydrophobicContact CD1-CG 3.86Å; Y293-F312 HydrophobicContact CE1-CB 4.07Å; Y293-F312 HydrophobicContact CE1-CD1 4.37Å; Y293-F312 HydrophobicContact CE1-CD2 4.07Å; Y293-F312 AromaticContact CE1-CG 3.91Å; Y293-F312 HydrophobicContact CE1-CG 3.91Å
294	Y	87.8	Confident	87.6	Confident	1 Å²	1	32.3 Å²	32.3	0%	0.004	19%	0.194	C	C	.	.	H	α-helix	trans	-75.3	-23.8	177.8	-59.4	-49.3	0	0	0	114.5	L75 V81 S84 L85 N225 N290 V291 A292 L302	L75-Y294 HydrophobicContact CD1-CE1 4.31Å; L75-Y294 HydrophobicContact CD2-CE1 3.91Å; V81-Y294 HydrophobicContact CG1-CD1 4Å; V81-Y294 HydrophobicContact CG1-CD2 3.47Å; V81-Y294 VanDerWaalsContact CG1-CD2 3.47Å; V81-Y294 HydrophobicContact CG1-CE1 4.27Å; V81-Y294 HydrophobicContact CG1-CE2 3.77Å; V81-Y294 HydrophobicContact CG1-CG 3.59Å; V81-Y294 HydrophobicContact CG2-CD1 4.08Å; V81-Y294 HydrophobicContact CG2-CE1 4.12Å; V81-Y294 HydrophobicContact CG2-CG 4.5Å; S84-Y294 WeakPolarHBondContact OG-CE2 3.36Å; S84-Y294 PolarHBondContact OG-OH 3.06Å; L85-Y294 HydrophobicContact CD2-CD2 4.31Å; L85-Y294 HydrophobicContact CD2-CE2 4.1Å; L85-Y294 HydrophobicContact CG-CE2 4.29Å; N225-Y294 WeakPolarHBondContact CB-O 3.22Å; N225-Y294 PolarHBondContact ND2-O 3.39Å; N290-Y294 HydrophobicContact CB-CE2 4.18Å; N290-Y294 WeakPolarHBondContact O-CD2 3.24Å; N290-Y294 PolarHBondContact O-N 2.85Å; V291-Y294 PolarHBondContact O-N 3.41Å; A292-Y294 PolarHBondContact O-N 2.98Å; Y294-L302 HydrophobicContact CD1-CD1 4.34Å; Y294-L302 HydrophobicContact CE1-CD1 3.83Å
295	T	85.7	Confident	87.1	Confident	9 Å²	9	29.7 Å²	29.7	6%	0.055	18%	0.175	C	C	.	.	H	α-helix	trans	-69.8	-34.9	171.1	55.7	0	0	0	0	112.4	L218 F226 V291 A292	L218-T295 HydrophobicContact CD2-CG2 3.89Å; L218-T295 HydrophobicContact CG-CG2 4.29Å; F226-T295 HydrophobicContact CE2-CG2 3.59Å; F226-T295 HydrophobicContact CZ-CG2 4.12Å; V291-T295 HydrophobicContact CG1-CG2 4.41Å; V291-T295 WeakPolarHBondContact O-CG2 3.45Å; V291-T295 PolarHBondContact O-N 3.39Å; A292-T295 PolarHBondContact O-N 2.61Å; A292-T295 PolarHBondContact O-OG1 3.03Å
296	V	84.3	Confident	86.4	Confident	27 Å²	27	34.5 Å²	34.5	16%	0.164	20%	0.196	C	C	.	.	H	α-helix	trans	-98.1	-34.1	-171.6	177.2	0	0	0	0	112.7	L217 A292 Y293 F312 R315 L316	L217-V296 HydrophobicContact CD1-CG2 3.65Å; L217-V296 HydrophobicContact CD2-CG2 4.37Å; A292-V296 PolarHBondContact O-N 3.16Å; Y293-V296 PolarHBondContact O-N 3.11Å; V296-F312 HydrophobicContact CB-CD2 3.83Å; V296-F312 HydrophobicContact CB-CE2 3.71Å; V296-F312 HydrophobicContact CG1-CD2 4.02Å; V296-F312 HydrophobicContact CG1-CE2 4.2Å; V296-F312 HydrophobicContact CG2-CD2 4.1Å; V296-F312 HydrophobicContact CG2-CE2 3.46Å; V296-F312 VanDerWaalsContact CG2-CE2 3.46Å; V296-F312 HydrophobicContact CG2-CZ 4.18Å; V296-R315 HydrophobicContact CG1-CB 3.41Å; V296-R315 VanDerWaalsContact CG1-CB 3.41Å; V296-R315 HydrophobicContact CG1-CG 4.19Å; V296-L316 HydrophobicContact CG1-CD1 4.35Å; V296-L316 HydrophobicContact CG2-CD1 3.78Å; V296-L316 HydrophobicContact CG2-CG 4.49Å
297	M	85.9	Confident	85.8	Confident	1 Å²	1	34.6 Å²	34.6	1%	0.005	20%	0.197	C	C	.	.	S	Bend	trans	-121	148	-174.9	-57.1	174.2	61.3	0	0	110.6	N225 Y293 E301 T311 F312 R315	N225-M297 PolarHBondContact ND2-O 3.24Å; Y293-M297 WeakPolarHBondContact O-CA 3.13Å; Y293-M297 WeakPolarHBondContact O-CB 3.25Å; Y293-M297 PolarHBondContact O-N 3.35Å; M297-E301 HydrophobicContact CE-CB 4.33Å; M297-E301 HydrophobicContact CE-CG 3.75Å; M297-T311 HydrophobicContact CE-CG2 3.34Å; M297-T311 HydrophobicContact SD-CG2 4.2Å; M297-F312 HydrophobicContact SD-CB 3.99Å; M297-R315 HydrophobicContact CG-CG 4.44Å
298	S	88.6	Confident	85.2	Confident	43 Å²	43	33.3 Å²	33.3	30%	0.301	19%	0.189	S	C	.	.			trans	-74.8	161.1	170.5	77.2	0	0	0	0	111	E300 E301 L302	S298-E300 VanDerWaalsContact C-N 3.25Å; S298-E300 PolarHBondContact O-N 3.22Å; S298-E301 PolarHBondContact O-N 2.71Å; S298-E301 WeakPolarHBondContact OG-CB 3.28Å; S298-E301 PolarHBondContact OG-N 3.18Å; S298-L302 PolarHBondContact O-N 2.62Å
299	A	86.4	Confident	84.8	Confident	34 Å²	34	29.8 Å²	29.8	28%	0.281	17%	0.171	S	C	.	.	H	α-helix	trans	-58.9	-38.5	175.9	0	0	0	0	0	112.3	L75 V81 L302 L303	L75-A299 HydrophobicContact CD1-CB 4.5Å; L75-A299 HydrophobicContact CD2-CB 4.03Å; V81-A299 HydrophobicContact CG2-CB 4.08Å; A299-L302 PolarHBondContact O-N 2.78Å; A299-L303 VanDerWaalsContact O-CG 3.3Å; A299-L303 WeakPolarHBondContact O-CG 3.4Å; A299-L303 PolarHBondContact O-N 3.49Å; A299-L303 VanDerWaalsContact O-N 3.14Å
300	E	87.4	Confident	84.4	Confident	162 Å²	162	29.8 Å²	29.8	76%	0.757	17%	0.171	S	C	*	.	H	α-helix	trans	-66.8	-42.1	178.4	-65.6	177.5	-177.1	0	0	111.7	S298 L303 A304	S298-E300 VanDerWaalsContact C-N 3.25Å; S298-E300 PolarHBondContact O-N 3.22Å; E300-L303 PolarHBondContact O-N 3.16Å; E300-A304 WeakPolarHBondContact O-CB 3.41Å; E300-A304 PolarHBondContact O-N 3.15Å
301	E	87.8	Confident	84.1	Confident	41 Å²	41	30.9 Å²	30.9	19%	0.192	18%	0.178	C	C	.	.	H	α-helix	trans	-65.3	-40.3	177.8	-170	179.6	-169.6	0	0	111.9	M297 S298 L303 A304 S305 T311 R315	M297-E301 HydrophobicContact CE-CB 4.33Å; M297-E301 HydrophobicContact CE-CG 3.75Å; S298-E301 PolarHBondContact O-N 2.71Å; S298-E301 WeakPolarHBondContact OG-CB 3.28Å; S298-E301 PolarHBondContact OG-N 3.18Å; E301-L303 VanDerWaalsContact C-N 3.3Å; E301-L303 PolarHBondContact O-N 2.9Å; E301-A304 PolarHBondContact O-N 3.07Å; E301-S305 WeakPolarHBondContact O-CB 3.24Å; E301-S305 PolarHBondContact O-N 2.94Å; E301-T311 HydrophobicContact CG-CG2 4.37Å; E301-R315 IonicContact OE1-CZ 2.66Å; E301-R315 IonicContact OE1-NE 3.94Å; E301-R315 PolarHBondContact OE1-NE 2.95Å; E301-R315 IonicContact OE1-NH2 3.65Å; E301-R315 PolarHBondContact OE1-NH2 3.38Å; E301-R315 IonicContact OE2-CZ 3.13Å; E301-R315 IonicContact OE2-NE 2.77Å; E301-R315 IonicContact OE2-NH2 3.53Å; E301-R315 PolarHBondContact OE2-NH2 2.9Å
302	L	88.3	Confident	83.8	Confident	0 Å²	0	30.2 Å²	30.2	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-62.2	-38.9	175.2	-166.1	152.7	0	0	0	111.6	P71 K72 L75 Y294 S298 A299 V308	P71-L302 HydrophobicContact CB-CD2 4.33Å; K72-L302 HydrophobicContact CB-CD2 4.18Å; L75-L302 HydrophobicContact CB-CD2 4.45Å; L75-L302 HydrophobicContact CD2-CB 4.13Å; L75-L302 HydrophobicContact CD2-CD2 3.82Å; L75-L302 HydrophobicContact CD2-CG 4.37Å; Y294-L302 HydrophobicContact CD1-CD1 4.34Å; Y294-L302 HydrophobicContact CE1-CD1 3.83Å; S298-L302 PolarHBondContact O-N 2.62Å; A299-L302 PolarHBondContact O-N 2.78Å; L302-V308 HydrophobicContact CD1-CG1 4.18Å; L302-V308 HydrophobicContact CD2-CG2 4.26Å; L302-V308 HydrophobicContact CG-CG1 4.09Å; L302-V308 HydrophobicContact CG-CG2 4.27Å
303	L	88.3	Confident	83.5	Confident	63 Å²	63	30.3 Å²	30.3	33%	0.33	17%	0.174	S	C	.	.	H	α-helix	trans	-71.5	-33.4	176.7	-68.5	176.2	0	0	0	112.9	K72 L75 K76 A299 E300 E301	K72-L303 WeakPolarHBondContact CE-O 3.46Å; K72-L303 HydrophobicContact CG-CD2 4.42Å; K72-L303 PolarHBondContact NZ-O 3.02Å; L75-L303 HydrophobicContact CB-CD2 4.17Å; L75-L303 HydrophobicContact CD2-CD2 4.11Å; L75-L303 HydrophobicContact CD2-CG 3.96Å; L75-L303 HydrophobicContact CG-CD2 4.09Å; L75-L303 HydrophobicContact CG-CG 4.28Å; K76-L303 HydrophobicContact CB-CD2 3.74Å; A299-L303 VanDerWaalsContact O-CG 3.3Å; A299-L303 WeakPolarHBondContact O-CG 3.4Å; A299-L303 PolarHBondContact O-N 3.49Å; A299-L303 VanDerWaalsContact O-N 3.14Å; E300-L303 PolarHBondContact O-N 3.16Å; E301-L303 VanDerWaalsContact C-N 3.3Å; E301-L303 PolarHBondContact O-N 2.9Å
304	A	86.9	Confident	83.2	Confident	77 Å²	77	34.2 Å²	34.2	64%	0.636	19%	0.192	S	C	*	.	H	α-helix	trans	-71.8	-36.2	175.7	0	0	0	0	0	111.9	E300 E301 E306	E300-A304 WeakPolarHBondContact O-CB 3.41Å; E300-A304 PolarHBondContact O-N 3.15Å; E301-A304 PolarHBondContact O-N 3.07Å; A304-E306 PolarHBondContact O-N 3.36Å
305	S	81.3	Confident	82.9	Confident	10 Å²	10	41.2 Å²	41.2	7%	0.07	22%	0.218	C	C	.	.			trans	-61.7	132.1	-178.6	179.9	0	0	0	0	112.4	K72 E301 A307 V308 T311	K72-S305 WeakPolarHBondContact CD-O 3.25Å; K72-S305 PolarHBondContact NZ-O 3.48Å; E301-S305 WeakPolarHBondContact O-CB 3.24Å; E301-S305 PolarHBondContact O-N 2.94Å; S305-A307 PolarHBondContact OG-N 2.99Å; S305-A307 PolarHBondContact OG-O 3.16Å; S305-V308 PolarHBondContact OG-N 3.36Å; S305-T311 WeakPolarHBondContact CB-OG1 3.32Å; S305-T311 PolarHBondContact OG-OG1 2.78Å
306	E	72.9	Confident	82.5	Confident	118 Å²	118	43.6 Å²	43.6	55%	0.551	23%	0.23	S	C	*	.	S	Bend	trans	-83.3	-25.5	171.1	-57.5	-162.8	109	0	0	112.7	R153 A304	R153-E306 IonicContact CZ-OE2 3.33Å; R153-E306 IonicContact NH2-OE1 3.58Å; R153-E306 PolarHBondContact NH2-OE1 2.69Å; R153-E306 IonicContact NH2-OE2 3.85Å; R153-E306 PolarHBondContact NH2-OE2 3.4Å; A304-E306 PolarHBondContact O-N 3.36Å
307	A	76.9	Confident	82.1	Confident	3 Å²	3	45.8 Å²	45.8	3%	0.025	24%	0.241	C	C	.	.	S	Bend	trans	-134.1	87.5	-179.5	0	0	0	0	0	110.2	Y154 S305 A309 V310 T311	Y154-A307 HydrophobicContact CE1-CB 4Å; S305-A307 PolarHBondContact OG-N 2.99Å; S305-A307 PolarHBondContact OG-O 3.16Å; A307-A309 PolarHBondContact O-N 3.38Å; A307-A309 VanDerWaalsContact O-N 3.11Å; A307-V310 HydrophobicContact CB-CB 4.15Å; A307-V310 HydrophobicContact CB-CG2 3.98Å; A307-V310 PolarHBondContact O-N 3Å; A307-T311 PolarHBondContact O-N 3.36Å
308	V	80.1	Confident	81.8	Confident	3 Å²	3	47.6 Å²	47.6	2%	0.018	26%	0.259	C	S	.	.	H	α-helix	trans	-53.7	-39.4	-172.1	-179	0	0	0	0	112.5	K72 Y293 L302 S305 V310 F312	K72-V308 HydrophobicContact CB-CG2 4.4Å; Y293-V308 HydrophobicContact CD1-CG1 4.25Å; Y293-V308 HydrophobicContact CD2-CG1 3.93Å; Y293-V308 HydrophobicContact CE1-CG1 4.3Å; Y293-V308 HydrophobicContact CE2-CG1 3.97Å; Y293-V308 HydrophobicContact CG-CG1 4.07Å; L302-V308 HydrophobicContact CD1-CG1 4.18Å; L302-V308 HydrophobicContact CD2-CG2 4.26Å; L302-V308 HydrophobicContact CG-CG1 4.09Å; L302-V308 HydrophobicContact CG-CG2 4.27Å; S305-V308 PolarHBondContact OG-N 3.36Å; V308-V310 VanDerWaalsContact C-N 3.33Å; V308-V310 PolarHBondContact O-N 3.04Å; V308-F312 VanDerWaalsContact O-CB 3.31Å; V308-F312 WeakPolarHBondContact O-CB 3.45Å; V308-F312 PolarHBondContact O-N 3.2Å
309	A	78.3	Confident	81	Confident	3 Å²	3	53.2 Å²	53.2	3%	0.025	29%	0.286	C	S	.	.	H	α-helix	trans	-64.5	-36.1	179.4	0	0	0	0	0	113.2	F68 A307 A313 V324 V328	F68-A309 HydrophobicContact CD1-CB 3.67Å; F68-A309 HydrophobicContact CE1-CB 4.14Å; F68-A309 HydrophobicContact CG-CB 4.33Å; A307-A309 PolarHBondContact O-N 3.38Å; A307-A309 VanDerWaalsContact O-N 3.11Å; A309-A313 WeakPolarHBondContact O-CB 3.07Å; A309-A313 PolarHBondContact O-N 3.34Å; A309-A313 VanDerWaalsContact O-N 3.12Å; A309-V324 HydrophobicContact CB-CG1 4.11Å; A309-V328 HydrophobicContact CB-CG2 4.3Å
310	V	78.1	Confident	80.3	Confident	3 Å²	3	58.7 Å²	58.7	2%	0.018	30%	0.304	C	S	.	.	H	α-helix	trans	-73.4	-48.5	-178.8	178.8	0	0	0	0	109.6	Y154 E157 M161 A307 V308 F312 A313 E314 P325	Y154-V310 HydrophobicContact CD1-CG2 4.11Å; Y154-V310 HydrophobicContact CE1-CG2 3.96Å; E157-V310 HydrophobicContact CG-CG1 4.36Å; E157-V310 HydrophobicContact CG-CG2 4.31Å; M161-V310 HydrophobicContact CE-CG1 4.24Å; M161-V310 HydrophobicContact SD-CG1 3.92Å; A307-V310 HydrophobicContact CB-CB 4.15Å; A307-V310 HydrophobicContact CB-CG2 3.98Å; A307-V310 PolarHBondContact O-N 3Å; V308-V310 VanDerWaalsContact C-N 3.33Å; V308-V310 PolarHBondContact O-N 3.04Å; V310-F312 VanDerWaalsContact C-N 3.28Å; V310-F312 PolarHBondContact O-N 2.94Å; V310-A313 CarbonylContact O-C 3.58Å; V310-A313 WeakPolarHBondContact O-CA 3.44Å; V310-A313 VanDerWaalsContact O-CB 3.32Å; V310-A313 WeakPolarHBondContact O-CB 3.45Å; V310-A313 PolarHBondContact O-N 2.93Å; V310-E314 WeakPolarHBondContact O-CG 3.17Å; V310-E314 PolarHBondContact O-N 3.01Å; V310-P325 HydrophobicContact CG2-CB 3.92Å; V310-P325 HydrophobicContact CG2-CG 4.19Å
311	T	81.6	Confident	79.6	Confident	23 Å²	23	51.5 Å²	51.5	14%	0.141	27%	0.271	C	S	.	.	H	α-helix	trans	-61.7	-38.2	178.2	-47.9	0	0	0	0	111.9	M297 E301 S305 A307 A313 E314 R315	M297-T311 HydrophobicContact CE-CG2 3.34Å; M297-T311 HydrophobicContact SD-CG2 4.2Å; E301-T311 HydrophobicContact CG-CG2 4.37Å; S305-T311 WeakPolarHBondContact CB-OG1 3.32Å; S305-T311 PolarHBondContact OG-OG1 2.78Å; A307-T311 PolarHBondContact O-N 3.36Å; T311-A313 VanDerWaalsContact C-N 3.33Å; T311-A313 PolarHBondContact O-N 3.36Å; T311-E314 PolarHBondContact O-N 3.05Å; T311-R315 WeakPolarHBondContact O-CG 3.4Å; T311-R315 PolarHBondContact O-N 3.4Å; T311-R315 VanDerWaalsContact O-N 3.16Å
312	F	81.3	Confident	79.1	Confident	12 Å²	12	52.8 Å²	52.8	5%	0.053	28%	0.282	C	S	.	.	H	α-helix	trans	-59.6	-43.9	171.4	177.6	-94.2	0	0	0	111.8	L210 A292 Y293 V296 M297 V308 V310 R315 L316	L210-F312 HydrophobicContact CD2-CD1 3.95Å; L210-F312 HydrophobicContact CD2-CE1 3.19Å; L210-F312 HydrophobicContact CD2-CZ 3.75Å; A292-F312 HydrophobicContact CB-CE2 3.98Å; A292-F312 HydrophobicContact CB-CZ 4.11Å; Y293-F312 HydrophobicContact CD1-CB 4.1Å; Y293-F312 AromaticContact CD1-CD2 3.57Å; Y293-F312 HydrophobicContact CD1-CD2 3.57Å; Y293-F312 HydrophobicContact CD1-CE2 4.07Å; Y293-F312 AromaticContact CD1-CG 3.86Å; Y293-F312 HydrophobicContact CD1-CG 3.86Å; Y293-F312 HydrophobicContact CE1-CB 4.07Å; Y293-F312 HydrophobicContact CE1-CD1 4.37Å; Y293-F312 HydrophobicContact CE1-CD2 4.07Å; Y293-F312 AromaticContact CE1-CG 3.91Å; Y293-F312 HydrophobicContact CE1-CG 3.91Å; V296-F312 HydrophobicContact CB-CD2 3.83Å; V296-F312 HydrophobicContact CB-CE2 3.71Å; V296-F312 HydrophobicContact CG1-CD2 4.02Å; V296-F312 HydrophobicContact CG1-CE2 4.2Å; V296-F312 HydrophobicContact CG2-CD2 4.1Å; V296-F312 HydrophobicContact CG2-CE2 3.46Å; V296-F312 VanDerWaalsContact CG2-CE2 3.46Å; V296-F312 HydrophobicContact CG2-CZ 4.18Å; M297-F312 HydrophobicContact SD-CB 3.99Å; V308-F312 VanDerWaalsContact O-CB 3.31Å; V308-F312 WeakPolarHBondContact O-CB 3.45Å; V308-F312 PolarHBondContact O-N 3.2Å; V310-F312 VanDerWaalsContact C-N 3.28Å; V310-F312 PolarHBondContact O-N 2.94Å; F312-R315 PolarHBondContact O-N 2.95Å; F312-L316 HydrophobicContact CD1-CD1 4.11Å; F312-L316 HydrophobicContact CD2-CD1 4.34Å; F312-L316 HydrophobicContact CE1-CD1 3.33Å; F312-L316 HydrophobicContact CE2-CD1 3.67Å; F312-L316 HydrophobicContact CZ-CD1 3.1Å; F312-L316 PolarHBondContact O-N 3.44Å
313	A	78.5	Confident	78.6	Confident	2 Å²	2	56 Å²	56	2%	0.017	30%	0.301	C	S	.	.	H	α-helix	trans	-66	-39	178.8	0	0	0	0	0	112.9	A309 V310 T311 R315 L316 L317 V324	A309-A313 WeakPolarHBondContact O-CB 3.07Å; A309-A313 PolarHBondContact O-N 3.34Å; A309-A313 VanDerWaalsContact O-N 3.12Å; V310-A313 CarbonylContact O-C 3.58Å; V310-A313 WeakPolarHBondContact O-CA 3.44Å; V310-A313 VanDerWaalsContact O-CB 3.32Å; V310-A313 WeakPolarHBondContact O-CB 3.45Å; V310-A313 PolarHBondContact O-N 2.93Å; T311-A313 VanDerWaalsContact C-N 3.33Å; T311-A313 PolarHBondContact O-N 3.36Å; A313-R315 VanDerWaalsContact C-N 3.33Å; A313-R315 PolarHBondContact O-N 3.43Å; A313-L316 PolarHBondContact O-N 3.31Å; A313-L317 WeakPolarHBondContact O-CB 3.34Å; A313-L317 PolarHBondContact O-N 3.17Å; A313-V324 HydrophobicContact CB-CB 3.66Å; A313-V324 HydrophobicContact CB-CG1 4.15Å; A313-V324 HydrophobicContact CB-CG2 3.39Å
314	E	80.8	Confident	78.1	Confident	83 Å²	83	53.8 Å²	53.8	39%	0.388	29%	0.291	S	S	.	.	H	α-helix	trans	-59.4	-44.4	175.2	-70.3	177.5	140.5	0	0	111.6	V310 T311 L316 G318	V310-E314 WeakPolarHBondContact O-CG 3.17Å; V310-E314 PolarHBondContact O-N 3.01Å; T311-E314 PolarHBondContact O-N 3.05Å; E314-L316 VanDerWaalsContact C-N 3.31Å; E314-L316 PolarHBondContact O-N 3.05Å; E314-G318 WeakPolarHBondContact O-CA 3.44Å; E314-G318 PolarHBondContact O-N 3.14Å
315	R	80.9	Confident	77.8	Confident	149 Å²	149	50.1 Å²	50.1	56%	0.562	26%	0.26	S	S	*	.	H	α-helix	trans	-65	-33.6	178.2	-70.8	-64.8	-167.4	142.3	-1.8	113.4	V296 M297 E301 T311 F312 A313	V296-R315 HydrophobicContact CG1-CB 3.41Å; V296-R315 VanDerWaalsContact CG1-CB 3.41Å; V296-R315 HydrophobicContact CG1-CG 4.19Å; M297-R315 HydrophobicContact CG-CG 4.44Å; E301-R315 IonicContact OE1-CZ 2.66Å; E301-R315 IonicContact OE1-NE 3.94Å; E301-R315 PolarHBondContact OE1-NE 2.95Å; E301-R315 IonicContact OE1-NH2 3.65Å; E301-R315 PolarHBondContact OE1-NH2 3.38Å; E301-R315 IonicContact OE2-CZ 3.13Å; E301-R315 IonicContact OE2-NE 2.77Å; E301-R315 IonicContact OE2-NH2 3.53Å; E301-R315 PolarHBondContact OE2-NH2 2.9Å; T311-R315 WeakPolarHBondContact O-CG 3.4Å; T311-R315 PolarHBondContact O-N 3.4Å; T311-R315 VanDerWaalsContact O-N 3.16Å; F312-R315 PolarHBondContact O-N 2.95Å; A313-R315 VanDerWaalsContact C-N 3.33Å; A313-R315 PolarHBondContact O-N 3.43Å
316	L	78.4	Confident	77.8	Confident	58 Å²	58	53.3 Å²	53.3	30%	0.304	28%	0.279	S	S	.	.	H	α-helix	trans	-95.2	-41.2	-172	-120.2	149.6	0	0	0	114.1	I213 L217 V296 F312 A313 E314	I213-L316 HydrophobicContact CD1-CD2 4.25Å; I213-L316 HydrophobicContact CG1-CD2 4.48Å; I213-L316 HydrophobicContact CG2-CD1 3.57Å; I213-L316 HydrophobicContact CG2-CD2 3.58Å; I213-L316 HydrophobicContact CG2-CG 4.2Å; L217-L316 HydrophobicContact CD1-CD1 4.35Å; V296-L316 HydrophobicContact CG1-CD1 4.35Å; V296-L316 HydrophobicContact CG2-CD1 3.78Å; V296-L316 HydrophobicContact CG2-CG 4.49Å; F312-L316 HydrophobicContact CD1-CD1 4.11Å; F312-L316 HydrophobicContact CD2-CD1 4.34Å; F312-L316 HydrophobicContact CE1-CD1 3.33Å; F312-L316 HydrophobicContact CE2-CD1 3.67Å; F312-L316 HydrophobicContact CZ-CD1 3.1Å; F312-L316 PolarHBondContact O-N 3.44Å; A313-L316 PolarHBondContact O-N 3.31Å; E314-L316 VanDerWaalsContact C-N 3.31Å; E314-L316 PolarHBondContact O-N 3.05Å
317	L	75.7	Confident	78.1	Confident	74 Å²	74	50.9 Å²	50.9	39%	0.387	27%	0.267	S	S	.	.	H	α-helix	trans	-112	-8.7	-168.3	-63	176.9	0	0	0	112.9	A313 N319 F320 V324	A313-L317 WeakPolarHBondContact O-CB 3.34Å; A313-L317 PolarHBondContact O-N 3.17Å; L317-N319 PolarHBondContact O-N 3.28Å; L317-N319 VanDerWaalsContact O-N 3.12Å; L317-F320 HydrophobicContact CB-CB 3.98Å; L317-F320 PolarHBondContact O-N 3.46Å; L317-F320 VanDerWaalsContact O-N 3.13Å; L317-V324 HydrophobicContact CD1-CG2 4.4Å
318	G	78.3	Confident	78.1	Confident	38 Å²	38	50.8 Å²	50.8	39%	0.392	27%	0.266	S	S	.	.	G	3₁₀ helix	trans	53.7	-117.1	-176.5	0	0	0	0	0	111	E314 F320 S321	E314-G318 WeakPolarHBondContact O-CA 3.44Å; E314-G318 PolarHBondContact O-N 3.14Å; G318-F320 PolarHBondContact O-N 3.4Å; G318-F320 VanDerWaalsContact O-N 3.13Å; G318-S321 WeakPolarHBondContact O-CB 2.98Å; G318-S321 PolarHBondContact O-N 3.35Å; G318-S321 PolarHBondContact O-OG 2.87Å; G318-S321 VanDerWaalsContact O-OG 3.08Å
319	N	73.4	Confident	78.2	Confident	162 Å²	162	50.9 Å²	50.9	87%	0.866	27%	0.267	S	S	*	.	G	3₁₀ helix	trans	-62.5	-19.9	-177.8	-66.7	-3.1	0	0	0	114.7	L317 S321	L317-N319 PolarHBondContact O-N 3.28Å; L317-N319 VanDerWaalsContact O-N 3.12Å; N319-S321 PolarHBondContact O-N 3.42Å
320	F	70.6	Confident	78.3	Confident	149 Å²	149	53.9 Å²	53.9	65%	0.654	28%	0.282	S	S	*	.	G	3₁₀ helix	trans	-84	4.4	175.1	-72.2	-81.9	0	0	0	113.2	L317 G318 V322 V323	L317-F320 HydrophobicContact CB-CB 3.98Å; L317-F320 PolarHBondContact O-N 3.46Å; L317-F320 VanDerWaalsContact O-N 3.13Å; G318-F320 PolarHBondContact O-N 3.4Å; G318-F320 VanDerWaalsContact O-N 3.13Å; F320-V322 PolarHBondContact O-N 3.27Å; F320-V323 WeakPolarHBondContact O-CB 3.43Å; F320-V323 WeakPolarHBondContact O-CG2 3.45Å; F320-V323 PolarHBondContact O-N 3.45Å
321	S	72.9	Confident	78.4	Confident	10 Å²	10	53.9 Å²	53.9	7%	0.07	28%	0.282	C	S	.	.	G	3₁₀ helix	trans	-59	-28.8	179.8	64.5	0	0	0	0	113.9	G318 N319 V323 V324 P325	G318-S321 WeakPolarHBondContact O-CB 2.98Å; G318-S321 PolarHBondContact O-N 3.35Å; G318-S321 PolarHBondContact O-OG 2.87Å; G318-S321 VanDerWaalsContact O-OG 3.08Å; N319-S321 PolarHBondContact O-N 3.42Å; S321-V323 PolarHBondContact O-N 2.81Å; S321-V323 VanDerWaalsContact O-N 3.1Å; S321-V324 PolarHBondContact O-N 2.87Å; S321-V324 VanDerWaalsContact O-N 3.16Å; S321-P325 WeakPolarHBondContact O-CD 3.42Å
322	V	77.4	Confident	78.3	Confident	68 Å²	68	52.8 Å²	52.8	41%	0.412	28%	0.275	S	S	.	.	G	3₁₀ helix	trans	-58.2	-23.8	178.4	177.5	0	0	0	0	113	P158 F320 P325 V326	P158-V322 HydrophobicContact CB-CG1 3.96Å; P158-V322 HydrophobicContact CG-CG1 4.24Å; F320-V322 PolarHBondContact O-N 3.27Å; V322-P325 WeakPolarHBondContact O-CD 3.25Å; V322-P325 WeakPolarHBondContact O-CG 3.36Å; V322-V326 WeakPolarHBondContact O-CG2 3.17Å
323	V	77.7	Confident	78.2	Confident	67 Å²	67	53.7 Å²	53.7	41%	0.406	28%	0.28	S	S	.	.	H	α-helix	trans	-69.1	-35.2	-179.3	175.2	0	0	0	0	111.9	F320 S321 V326 F327	F320-V323 WeakPolarHBondContact O-CB 3.43Å; F320-V323 WeakPolarHBondContact O-CG2 3.45Å; F320-V323 PolarHBondContact O-N 3.45Å; S321-V323 PolarHBondContact O-N 2.81Å; S321-V323 VanDerWaalsContact O-N 3.1Å; V323-V326 PolarHBondContact O-N 3.06Å; V323-F327 HydrophobicContact CG1-CD2 3.5Å; V323-F327 VanDerWaalsContact CG1-CD2 3.5Å; V323-F327 HydrophobicContact CG1-CE2 3.2Å; V323-F327 HydrophobicContact CG1-CZ 4.33Å; V323-F327 WeakPolarHBondContact O-CD2 3.27Å; V323-F327 PolarHBondContact O-N 3.19Å; V323-F327 VanDerWaalsContact O-N 3.09Å
324	V	78.3	Confident	78.1	Confident	18 Å²	18	53.9 Å²	53.9	11%	0.109	28%	0.281	C	S	.	.	H	α-helix	trans	-66.4	-50.7	-177.2	176.6	0	0	0	0	113.7	A309 A313 L317 S321 V326 F327 V328	A309-V324 HydrophobicContact CB-CG1 4.11Å; A313-V324 HydrophobicContact CB-CB 3.66Å; A313-V324 HydrophobicContact CB-CG1 4.15Å; A313-V324 HydrophobicContact CB-CG2 3.39Å; L317-V324 HydrophobicContact CD1-CG2 4.4Å; S321-V324 PolarHBondContact O-N 2.87Å; S321-V324 VanDerWaalsContact O-N 3.16Å; V324-V326 PolarHBondContact O-N 2.97Å; V324-F327 PolarHBondContact O-N 3.44Å; V324-F327 VanDerWaalsContact O-N 3.09Å; V324-V328 HydrophobicContact CG1-CG2 4.31Å; V324-V328 WeakPolarHBondContact O-CG2 3.38Å; V324-V328 PolarHBondContact O-N 3.36Å
325	P	79.6	Confident	77.9	Confident	0 Å²	0	51.2 Å²	51.2	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-59.5	-33.2	176.6	18.9	-28.1	0	0	0	112.5	Y154 P158 V310 S321 V322 V328 A329	Y154-P325 HydrophobicContact CD1-CB 4.17Å; Y154-P325 WeakPolarHBondContact O-CB 3.41Å; P158-P325 HydrophobicContact CG-CB 4.12Å; P158-P325 HydrophobicContact CG-CG 3.66Å; V310-P325 HydrophobicContact CG2-CB 3.92Å; V310-P325 HydrophobicContact CG2-CG 4.19Å; S321-P325 WeakPolarHBondContact O-CD 3.42Å; V322-P325 WeakPolarHBondContact O-CD 3.25Å; V322-P325 WeakPolarHBondContact O-CG 3.36Å; P325-V328 PolarHBondContact O-N 3.34Å; P325-A329 WeakPolarHBondContact O-CB 3.26Å; P325-A329 PolarHBondContact O-N 3.1Å
326	V	81.7	Confident	77.8	Confident	76 Å²	76	44.1 Å²	44.1	46%	0.461	25%	0.245	S	C	.	.	H	α-helix	trans	-64.7	-45	173.8	176.3	0	0	0	0	111.3	V322 V323 V324 V328 A329 L330	V322-V326 WeakPolarHBondContact O-CG2 3.17Å; V323-V326 PolarHBondContact O-N 3.06Å; V324-V326 PolarHBondContact O-N 2.97Å; V326-V328 PolarHBondContact O-N 3.41Å; V326-A329 PolarHBondContact O-N 3.27Å; V326-L330 HydrophobicContact CG1-CD1 4.35Å; V326-L330 WeakPolarHBondContact O-CG 3.42Å; V326-L330 PolarHBondContact O-N 3.29Å
327	F	78.9	Confident	77.7	Confident	68 Å²	68	41.6 Å²	41.6	30%	0.298	23%	0.232	S	C	.	.	H	α-helix	trans	-63.9	-39.4	175.2	-80.6	-60.2	0	0	0	112.6	L202 V323 V324 L330 S331	L202-F327 HydrophobicContact CB-CD1 4.42Å; L202-F327 HydrophobicContact CD1-CD1 4.18Å; L202-F327 HydrophobicContact CD1-CE1 3.95Å; L202-F327 HydrophobicContact CD2-CE1 3.81Å; L202-F327 HydrophobicContact CG-CE1 4.31Å; V323-F327 HydrophobicContact CG1-CD2 3.5Å; V323-F327 VanDerWaalsContact CG1-CD2 3.5Å; V323-F327 HydrophobicContact CG1-CE2 3.2Å; V323-F327 HydrophobicContact CG1-CZ 4.33Å; V323-F327 WeakPolarHBondContact O-CD2 3.27Å; V323-F327 PolarHBondContact O-N 3.19Å; V323-F327 VanDerWaalsContact O-N 3.09Å; V324-F327 PolarHBondContact O-N 3.44Å; V324-F327 VanDerWaalsContact O-N 3.09Å; F327-L330 HydrophobicContact CD1-CD1 4.32Å; F327-L330 PolarHBondContact O-N 3.47Å; F327-S331 WeakPolarHBondContact O-CB 3.41Å; F327-S331 PolarHBondContact O-N 2.9Å
328	V	78.3	Confident	77.4	Confident	0 Å²	0	40 Å²	40	0%	0	23%	0.234	C	C	.	.	H	α-helix	trans	-66.4	-38.9	175.8	179.4	0	0	0	0	111	F68 Y154 A309 V324 P325 V326 S331 C332	F68-V328 HydrophobicContact CD2-CG1 3.91Å; F68-V328 HydrophobicContact CD2-CG2 4.31Å; F68-V328 HydrophobicContact CE1-CG2 4.42Å; F68-V328 HydrophobicContact CE2-CG1 4.16Å; F68-V328 HydrophobicContact CE2-CG2 4.06Å; F68-V328 HydrophobicContact CZ-CG2 4.1Å; Y154-V328 HydrophobicContact CD1-CB 3.99Å; Y154-V328 HydrophobicContact CD1-CG1 3.85Å; Y154-V328 HydrophobicContact CD2-CB 4.4Å; Y154-V328 HydrophobicContact CD2-CG1 3.49Å; Y154-V328 VanDerWaalsContact CD2-CG1 3.49Å; Y154-V328 HydrophobicContact CE1-CB 4.26Å; Y154-V328 HydrophobicContact CE1-CG1 3.88Å; Y154-V328 HydrophobicContact CE1-CG2 4.48Å; Y154-V328 HydrophobicContact CE2-CG1 3.57Å; Y154-V328 HydrophobicContact CG-CB 4.07Å; Y154-V328 HydrophobicContact CG-CG1 3.66Å; A309-V328 HydrophobicContact CB-CG2 4.3Å; V324-V328 HydrophobicContact CG1-CG2 4.31Å; V324-V328 WeakPolarHBondContact O-CG2 3.38Å; V324-V328 PolarHBondContact O-N 3.36Å; P325-V328 PolarHBondContact O-N 3.34Å; V326-V328 PolarHBondContact O-N 3.41Å; V328-S331 VanDerWaalsContact O-CB 3.23Å; V328-S331 WeakPolarHBondContact O-CB 3.46Å; V328-S331 PolarHBondContact O-N 3.39Å; V328-C332 PolarHBondContact O-N 3.28Å; V328-C332 PolarHBondContact O-SG 3.02Å
329	A	82	Confident	77.1	Confident	5 Å²	5	39 Å²	39	4%	0.041	22%	0.223	C	C	.	.	H	α-helix	trans	-62.4	-45.5	172.8	0	0	0	0	0	111.1	F151 I155 P325 V326 S331 C332 F333	F151-A329 HydrophobicContact CD2-CB 3.87Å; F151-A329 VanDerWaalsContact CD2-O 3.29Å; F151-A329 WeakPolarHBondContact CD2-O 3.38Å; F151-A329 HydrophobicContact CE2-CB 4.01Å; I155-A329 HydrophobicContact CB-CB 4.46Å; P325-A329 WeakPolarHBondContact O-CB 3.26Å; P325-A329 PolarHBondContact O-N 3.1Å; V326-A329 PolarHBondContact O-N 3.27Å; A329-S331 VanDerWaalsContact C-N 3.29Å; A329-S331 PolarHBondContact O-N 3.08Å; A329-C332 PolarHBondContact O-N 2.87Å; A329-C332 VanDerWaalsContact O-N 3.17Å; A329-F333 PolarHBondContact O-N 2.81Å
330	L	80.3	Confident	77.1	Confident	67 Å²	67	31.7 Å²	31.7	35%	0.351	18%	0.184	S	C	.	.	H	α-helix	trans	-58.3	-41.6	174.1	-71.8	171.4	0	0	0	111.7	T199 L202 V326 F327 C332 F333 G334	T199-L330 WeakPolarHBondContact CG2-O 2.93Å; L202-L330 HydrophobicContact CD1-CD1 4.28Å; V326-L330 HydrophobicContact CG1-CD1 4.35Å; V326-L330 WeakPolarHBondContact O-CG 3.42Å; V326-L330 PolarHBondContact O-N 3.29Å; F327-L330 HydrophobicContact CD1-CD1 4.32Å; F327-L330 PolarHBondContact O-N 3.47Å; L330-C332 PolarHBondContact O-N 3.43Å; L330-F333 VanDerWaalsContact O-CB 3.31Å; L330-F333 WeakPolarHBondContact O-CB 3.47Å; L330-F333 PolarHBondContact O-N 2.95Å; L330-G334 PolarHBondContact O-N 3.29Å
331	S	79.1	Confident	77.1	Confident	2 Å²	2	26.2 Å²	26.2	1%	0.014	16%	0.159	C	C	.	.	H	α-helix	trans	-56.3	-47.4	174.2	-172.5	0	0	0	0	112.8	N203 F327 V328 A329 F333 G334 S335	N203-S331 PolarHBondContact ND2-OG 3.37Å; N203-S331 WeakPolarHBondContact OD1-CB 3.4Å; N203-S331 PolarHBondContact OD1-OG 3.41Å; F327-S331 WeakPolarHBondContact O-CB 3.41Å; F327-S331 PolarHBondContact O-N 2.9Å; V328-S331 VanDerWaalsContact O-CB 3.23Å; V328-S331 WeakPolarHBondContact O-CB 3.46Å; V328-S331 PolarHBondContact O-N 3.39Å; A329-S331 VanDerWaalsContact C-N 3.29Å; A329-S331 PolarHBondContact O-N 3.08Å; S331-F333 VanDerWaalsContact C-N 3.33Å; S331-F333 PolarHBondContact O-N 3.49Å; S331-G334 PolarHBondContact O-N 2.92Å; S331-S335 PolarHBondContact O-N 3.45Å; S331-S335 PolarHBondContact O-OG 3.27Å
332	C	80	Confident	77	Confident	0 Å²	0	26.3 Å²	26.3	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-63.6	-40.9	177.3	-63.7	0	0	0	0	110.9	I147 F151 V328 A329 L330 G334 S335 M336	I147-C332 HydrophobicContact CG2-CB 4.02Å; I147-C332 WeakPolarHBondContact CG2-O 3.44Å; F151-C332 HydrophobicContact CB-CB 3.71Å; F151-C332 HydrophobicContact CD2-CB 4.46Å; V328-C332 PolarHBondContact O-N 3.28Å; V328-C332 PolarHBondContact O-SG 3.02Å; A329-C332 PolarHBondContact O-N 2.87Å; A329-C332 VanDerWaalsContact O-N 3.17Å; L330-C332 PolarHBondContact O-N 3.43Å; C332-G334 PolarHBondContact O-N 3.48Å; C332-S335 WeakPolarHBondContact O-CB 3.26Å; C332-S335 PolarHBondContact O-N 3.17Å; C332-M336 VanDerWaalsContact O-CG 3.3Å; C332-M336 WeakPolarHBondContact O-CG 3.37Å; C332-M336 PolarHBondContact O-N 3.34Å
333	F	80	Confident	76.8	Confident	32 Å²	32	23.3 Å²	23.3	14%	0.14	14%	0.143	C	C	.	.	H	α-helix	trans	-57	-47.4	174.9	-178.2	-79.2	0	0	0	111.8	I181 L184 V195 A329 L330 S331 S335 M336 N337	I181-F333 HydrophobicContact CD1-CD2 3.48Å; I181-F333 VanDerWaalsContact CD1-CD2 3.48Å; I181-F333 HydrophobicContact CD1-CE2 3.71Å; I181-F333 HydrophobicContact CD1-CG 4.16Å; I181-F333 HydrophobicContact CG1-CD2 3.61Å; I181-F333 HydrophobicContact CG1-CE2 3.24Å; I181-F333 HydrophobicContact CG1-CG 4.5Å; I181-F333 HydrophobicContact CG1-CZ 3.88Å; L184-F333 HydrophobicContact CD1-CZ 4.21Å; V195-F333 HydrophobicContact CG1-CD1 4.19Å; V195-F333 HydrophobicContact CG1-CE1 3.75Å; A329-F333 PolarHBondContact O-N 2.81Å; L330-F333 VanDerWaalsContact O-CB 3.31Å; L330-F333 WeakPolarHBondContact O-CB 3.47Å; L330-F333 PolarHBondContact O-N 2.95Å; S331-F333 VanDerWaalsContact C-N 3.33Å; S331-F333 PolarHBondContact O-N 3.49Å; F333-S335 VanDerWaalsContact C-N 3.33Å; F333-S335 PolarHBondContact O-N 3.03Å; F333-M336 PolarHBondContact O-N 3.49Å; F333-N337 PolarHBondContact O-N 2.94Å; F333-N337 VanDerWaalsContact O-N 3.17Å
334	G	75.9	Confident	76.6	Confident	5 Å²	5	20.8 Å²	20.8	5%	0.052	13%	0.128	C	C	.	.	H	α-helix	trans	-62.2	-40	176.1	0	0	0	0	0	112.7	L330 S331 C332 N337 G338	L330-G334 PolarHBondContact O-N 3.29Å; S331-G334 PolarHBondContact O-N 2.92Å; C332-G334 PolarHBondContact O-N 3.48Å; G334-N337 PolarHBondContact O-N 3.35Å; G334-G338 PolarHBondContact O-N 3.4Å
335	S	76.4	Confident	76.3	Confident	27 Å²	27	25.2 Å²	25.2	19%	0.189	14%	0.143	C	C	.	.	H	α-helix	trans	-66.5	-42.2	178.5	-59.9	0	0	0	0	112.6	S331 C332 F333 N337 G338 G339	S331-S335 PolarHBondContact O-N 3.45Å; S331-S335 PolarHBondContact O-OG 3.27Å; C332-S335 WeakPolarHBondContact O-CB 3.26Å; C332-S335 PolarHBondContact O-N 3.17Å; F333-S335 VanDerWaalsContact C-N 3.33Å; F333-S335 PolarHBondContact O-N 3.03Å; S335-N337 VanDerWaalsContact C-N 3.27Å; S335-N337 PolarHBondContact O-N 2.93Å; S335-G338 PolarHBondContact O-N 3.35Å; S335-G339 PolarHBondContact O-N 3.13Å
336	M	78.4	Confident	76	Confident	0 Å²	0	25.4 Å²	25.4	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-59.9	-40.6	175	-70.7	173.9	62.9	0	0	111.8	I147 S148 I178 I181 C332 F333 G339 H340	I147-M336 HydrophobicContact CB-CG 4.24Å; I147-M336 HydrophobicContact CG2-CG 3.61Å; S148-M336 WeakPolarHBondContact OG-CE 3.48Å; S148-M336 PolarHBondContact OG-SD 2.97Å; I178-M336 HydrophobicContact CB-CE 3.78Å; I178-M336 HydrophobicContact CD1-CE 4.16Å; I178-M336 HydrophobicContact CG1-CE 3.64Å; I181-M336 HydrophobicContact CD1-CB 4.25Å; I181-M336 HydrophobicContact CD1-CE 3.35Å; I181-M336 HydrophobicContact CD1-SD 3.61Å; C332-M336 VanDerWaalsContact O-CG 3.3Å; C332-M336 WeakPolarHBondContact O-CG 3.37Å; C332-M336 PolarHBondContact O-N 3.34Å; F333-M336 PolarHBondContact O-N 3.49Å; M336-G339 PolarHBondContact O-N 3.1Å; M336-H340 PolarHBondContact O-N 3.45Å; M336-H340 PolarHBondContact O-ND1 3.17Å
337	N	75.9	Confident	75.9	Confident	5 Å²	5	21.9 Å²	21.9	3%	0.027	12%	0.122	C	C	.	.	H	α-helix	trans	-68.5	-45.6	177.9	-177.5	44	0	0	0	112.2	N185 I192 F333 G334 S335 G339 H340 F341	N185-N337 PolarHBondContact ND2-OD1 3.24Å; N185-N337 PolarHBondContact OD1-OD1 3.43Å; N185-N337 VanDerWaalsContact OD1-OD1 3.1Å; I192-N337 HydrophobicContact CG2-CB 4.45Å; I192-N337 WeakPolarHBondContact CG2-ND2 3.45Å; I192-N337 WeakPolarHBondContact CG2-OD1 3.44Å; I192-N337 PolarHBondContact O-ND2 3.49Å; I192-N337 VanDerWaalsContact O-ND2 3.14Å; F333-N337 PolarHBondContact O-N 2.94Å; F333-N337 VanDerWaalsContact O-N 3.17Å; G334-N337 PolarHBondContact O-N 3.35Å; S335-N337 VanDerWaalsContact C-N 3.27Å; S335-N337 PolarHBondContact O-N 2.93Å; N337-G339 VanDerWaalsContact C-N 3.27Å; N337-G339 PolarHBondContact O-N 2.92Å; N337-H340 WeakPolarHBondContact O-CB 3.34Å; N337-H340 PolarHBondContact O-N 3.46Å; N337-H340 VanDerWaalsContact O-N 3.13Å; N337-F341 WeakPolarHBondContact O-CD2 3.04Å; N337-F341 PolarHBondContact O-N 3.44Å; N337-F341 VanDerWaalsContact OD1-CE2 3.32Å; N337-F341 WeakPolarHBondContact OD1-CE2 3.4Å
338	G	70.3	Confident	75.7	Confident	41 Å²	41	22.3 Å²	22.3	42%	0.423	12%	0.122	S	C	.	.	H	α-helix	trans	-58.2	-39.8	173.8	0	0	0	0	0	112.7	G334 S335 H340 F341 A342	G334-G338 PolarHBondContact O-N 3.4Å; S335-G338 PolarHBondContact O-N 3.35Å; G338-H340 VanDerWaalsContact C-N 3.3Å; G338-H340 PolarHBondContact O-N 3.39Å; G338-F341 PolarHBondContact O-N 3.44Å; G338-A342 PolarHBondContact O-N 3.3Å; G338-A342 VanDerWaalsContact O-N 3.12Å
339	G	72	Confident	75.6	Confident	16 Å²	16	22.8 Å²	22.8	17%	0.165	13%	0.125	C	C	.	.	H	α-helix	trans	-59.6	-37.1	175.5	0	0	0	0	0	113.6	S335 M336 N337 L343	S335-G339 PolarHBondContact O-N 3.13Å; M336-G339 PolarHBondContact O-N 3.1Å; N337-G339 VanDerWaalsContact C-N 3.27Å; N337-G339 PolarHBondContact O-N 2.92Å; G339-L343 PolarHBondContact O-N 3.33Å
340	H	73.8	Confident	75.5	Confident	10 Å²	10	22.5 Å²	22.5	5%	0.046	12%	0.123	C	C	.	.	H	α-helix	trans	-64.6	-48.5	176.4	-87.2	85.6	0	0	0	113.1	Y182 M336 N337 G338 A342 L343 S344	Y182-H340 AromaticContact CD1-NE2 3.89Å; Y182-H340 AromaticContact CD2-CE1 3.95Å; Y182-H340 AromaticContact CD2-NE2 3.87Å; Y182-H340 AromaticContact CE1-NE2 3.14Å; Y182-H340 WeakPolarHBondContact CE1-NE2 3.5Å; Y182-H340 AromaticContact CE2-CE1 3.32Å; Y182-H340 WeakPolarHBondContact CE2-CE1 3.46Å; Y182-H340 AromaticContact CE2-NE2 3.21Å; Y182-H340 WeakPolarHBondContact CE2-NE2 3.33Å; Y182-H340 AromaticContact CZ-CE1 3.43Å; Y182-H340 VanDerWaalsContact CZ-CE1 3.43Å; Y182-H340 AromaticContact CZ-NE2 2.82Å; Y182-H340 PolarHBondContact OH-NE2 2.94Å; M336-H340 PolarHBondContact O-N 3.45Å; M336-H340 PolarHBondContact O-ND1 3.17Å; N337-H340 WeakPolarHBondContact O-CB 3.34Å; N337-H340 PolarHBondContact O-N 3.46Å; N337-H340 VanDerWaalsContact O-N 3.13Å; G338-H340 VanDerWaalsContact C-N 3.3Å; G338-H340 PolarHBondContact O-N 3.39Å; H340-A342 VanDerWaalsContact C-N 3.31Å; H340-A342 PolarHBondContact O-N 2.96Å; H340-L343 PolarHBondContact O-N 3.03Å; H340-S344 PolarHBondContact O-N 2.94Å; H340-S344 VanDerWaalsContact O-N 3.1Å
341	F	70.4	Confident	75.5	Confident	33 Å²	33	19.8 Å²	19.8	15%	0.145	11%	0.11	C	C	.	.	H	α-helix	trans	-66	-34.2	179.4	-73.3	-69.4	0	0	0	112.8	V189 I192 E193 N337 G338 L343 S344 R345	V189-F341 HydrophobicContact CG1-CE1 3.88Å; V189-F341 HydrophobicContact CG1-CZ 3.91Å; V189-F341 HydrophobicContact CG2-CE1 4.37Å; V189-F341 HydrophobicContact CG2-CZ 4.3Å; I192-F341 HydrophobicContact CG2-CE2 4.12Å; I192-F341 HydrophobicContact CG2-CZ 4.45Å; E193-F341 HydrophobicContact CG-CE2 4.31Å; E193-F341 HydrophobicContact CG-CZ 4.08Å; N337-F341 WeakPolarHBondContact O-CD2 3.04Å; N337-F341 PolarHBondContact O-N 3.44Å; N337-F341 VanDerWaalsContact OD1-CE2 3.32Å; N337-F341 WeakPolarHBondContact OD1-CE2 3.4Å; G338-F341 PolarHBondContact O-N 3.44Å; F341-L343 VanDerWaalsContact C-N 3.32Å; F341-S344 PolarHBondContact O-OG 3.25Å; F341-R345 WeakPolarHBondContact O-CG 3.41Å; F341-R345 PolarHBondContact O-N 2.97Å
342	A	70.2	Confident	75.5	Confident	13 Å²	13	25.5 Å²	25.5	11%	0.107	13%	0.131	C	C	.	.	H	α-helix	trans	-64.2	-39.4	175.6	0	0	0	0	0	111.7	Y256 G338 H340 M346	Y256-A342 HydrophobicContact CE1-CB 4.01Å; G338-A342 PolarHBondContact O-N 3.3Å; G338-A342 VanDerWaalsContact O-N 3.12Å; H340-A342 VanDerWaalsContact C-N 3.31Å; H340-A342 PolarHBondContact O-N 2.96Å; A342-M346 PolarHBondContact O-N 3.15Å
343	L	73.2	Confident	75.5	Confident	4 Å²	4	29.3 Å²	29.3	2%	0.021	15%	0.149	C	C	.	.	H	α-helix	trans	-69.7	-45.2	179.7	-174.7	112	0	0	0	112.4	R140 G339 H340 F341 R345 M346 F347 L377	R140-L343 HydrophobicContact CB-CD1 3.55Å; R140-L343 HydrophobicContact CG-CD1 3.59Å; G339-L343 PolarHBondContact O-N 3.33Å; H340-L343 PolarHBondContact O-N 3.03Å; F341-L343 VanDerWaalsContact C-N 3.32Å; L343-R345 VanDerWaalsContact C-N 3.28Å; L343-R345 PolarHBondContact O-N 3.07Å; L343-M346 WeakPolarHBondContact O-CA 3.45Å; L343-M346 WeakPolarHBondContact O-CB 3.47Å; L343-M346 PolarHBondContact O-N 2.96Å; L343-F347 HydrophobicContact CD1-CE1 4.02Å; L343-F347 HydrophobicContact CD1-CZ 3.91Å; L343-F347 HydrophobicContact CD2-CD2 4.27Å; L343-F347 HydrophobicContact CD2-CE1 4.02Å; L343-F347 HydrophobicContact CD2-CE2 3.51Å; L343-F347 HydrophobicContact CD2-CZ 3.32Å; L343-F347 HydrophobicContact CG-CD1 4.38Å; L343-F347 HydrophobicContact CG-CE1 3.76Å; L343-F347 HydrophobicContact CG-CE2 4.17Å; L343-F347 HydrophobicContact CG-CZ 3.59Å; L343-F347 PolarHBondContact O-N 3.36Å; L343-L377 HydrophobicContact CD1-CD1 3.89Å; L343-L377 HydrophobicContact CD1-CD2 4.34Å; L343-L377 HydrophobicContact CD2-CB 4.19Å; L343-L377 HydrophobicContact CD2-CD1 4.09Å; L343-L377 HydrophobicContact CD2-CD2 3.63Å; L343-L377 HydrophobicContact CD2-CG 4.18Å; L343-L377 HydrophobicContact CG-CD2 4.44Å
344	S	73	Confident	75.5	Confident	15 Å²	15	30.4 Å²	30.4	11%	0.105	17%	0.169	C	C	.	.	H	α-helix	trans	-60.9	-39.3	-179.9	59.4	0	0	0	0	112.3	H340 F341 M346 F347 Y348	H340-S344 PolarHBondContact O-N 2.94Å; H340-S344 VanDerWaalsContact O-N 3.1Å; F341-S344 PolarHBondContact O-OG 3.25Å; S344-M346 VanDerWaalsContact C-N 3.33Å; S344-M346 PolarHBondContact O-N 3.35Å; S344-F347 PolarHBondContact O-N 2.89Å; S344-Y348 PolarHBondContact O-N 2.92Å
345	R	71.8	Confident	75.9	Confident	111 Å²	111	30.6 Å²	30.6	42%	0.419	17%	0.169	S	C	.	.	H	α-helix	trans	-61.5	-40.1	171.9	-74.1	-179.6	176.2	130	-0.4	112.4	F341 L343 Y348 V349	F341-R345 WeakPolarHBondContact O-CG 3.41Å; F341-R345 PolarHBondContact O-N 2.97Å; L343-R345 VanDerWaalsContact C-N 3.28Å; L343-R345 PolarHBondContact O-N 3.07Å; R345-Y348 WeakPolarHBondContact O-CB 3.3Å; R345-Y348 PolarHBondContact O-N 3.39Å; R345-V349 WeakPolarHBondContact O-CG2 3.44Å; R345-V349 PolarHBondContact O-N 3.39Å
346	M	75.3	Confident	76.2	Confident	4 Å²	4	30.2 Å²	30.2	2%	0.02	16%	0.164	C	C	.	.	H	α-helix	trans	-65.4	-40.2	177.1	179.6	170.4	158.9	0	0	111.9	L132 D135 F259 A342 L343 S344 Y348 V349 A350	L132-M346 HydrophobicContact CB-CE 4.27Å; L132-M346 HydrophobicContact CD1-CE 3.33Å; L132-M346 HydrophobicContact CD1-CG 4.34Å; L132-M346 HydrophobicContact CG-CE 4.37Å; D135-M346 HydrophobicContact CB-CE 3.5Å; D135-M346 VanDerWaalsContact CB-CE 3.5Å; D135-M346 HydrophobicContact CB-SD 4.28Å; D135-M346 VanDerWaalsContact OD2-CE 3.28Å; D135-M346 WeakPolarHBondContact OD2-CE 3.22Å; F259-M346 HydrophobicContact CE1-SD 4.46Å; A342-M346 PolarHBondContact O-N 3.15Å; L343-M346 WeakPolarHBondContact O-CA 3.45Å; L343-M346 WeakPolarHBondContact O-CB 3.47Å; L343-M346 PolarHBondContact O-N 2.96Å; S344-M346 VanDerWaalsContact C-N 3.33Å; S344-M346 PolarHBondContact O-N 3.35Å; M346-Y348 VanDerWaalsContact C-N 3.34Å; M346-V349 PolarHBondContact O-N 3.11Å; M346-A350 WeakPolarHBondContact O-CB 3.31Å; M346-A350 PolarHBondContact O-N 3.49Å
347	F	79.2	Confident	76.2	Confident	2 Å²	2	33.1 Å²	33.1	1%	0.009	18%	0.184	C	C	.	.	H	α-helix	trans	-67.1	-37.4	175.5	-68.7	1.2	0	0	0	112.1	L136 L343 S344 A350 S351 L356 L360 A373	L136-F347 HydrophobicContact CD1-CD1 4.5Å; L136-F347 HydrophobicContact CD1-CE1 3.43Å; L136-F347 VanDerWaalsContact CD1-CE1 3.43Å; L136-F347 HydrophobicContact CD1-CE2 4.01Å; L136-F347 HydrophobicContact CD1-CZ 3.15Å; L343-F347 HydrophobicContact CD1-CE1 4.02Å; L343-F347 HydrophobicContact CD1-CZ 3.91Å; L343-F347 HydrophobicContact CD2-CD2 4.27Å; L343-F347 HydrophobicContact CD2-CE1 4.02Å; L343-F347 HydrophobicContact CD2-CE2 3.51Å; L343-F347 HydrophobicContact CD2-CZ 3.32Å; L343-F347 HydrophobicContact CG-CD1 4.38Å; L343-F347 HydrophobicContact CG-CE1 3.76Å; L343-F347 HydrophobicContact CG-CE2 4.17Å; L343-F347 HydrophobicContact CG-CZ 3.59Å; L343-F347 PolarHBondContact O-N 3.36Å; S344-F347 PolarHBondContact O-N 2.89Å; F347-A350 PolarHBondContact O-N 3.27Å; F347-S351 WeakPolarHBondContact O-CB 3.2Å; F347-S351 PolarHBondContact O-N 3.22Å; F347-L356 HydrophobicContact CB-CD1 4.28Å; F347-L356 HydrophobicContact CD1-CD1 3.95Å; F347-L356 HydrophobicContact CG-CD1 4.15Å; F347-L360 HydrophobicContact CD2-CB 4.44Å; F347-A373 HydrophobicContact CD2-CB 3.33Å; F347-A373 HydrophobicContact CE2-CB 3.69Å; F347-A373 HydrophobicContact CG-CB 4.4Å
348	Y	74.8	Confident	76.2	Confident	76 Å²	76	38.6 Å²	38.6	30%	0.298	21%	0.209	S	C	.	.	H	α-helix	trans	-57.6	-49.1	173.1	-179.8	-98.1	0	0	0	111.7	S344 R345 M346 R352 A502	S344-Y348 PolarHBondContact O-N 2.92Å; R345-Y348 WeakPolarHBondContact O-CB 3.3Å; R345-Y348 PolarHBondContact O-N 3.39Å; M346-Y348 VanDerWaalsContact C-N 3.34Å; Y348-R352 PolarHBondContact O-N 3.26Å; Y348-R352 VanDerWaalsContact O-N 3.09Å; Y348-A502 HydrophobicContact CE2-CB 3.73Å
349	V	75.1	Confident	76.5	Confident	10 Å²	10	36.9 Å²	36.9	6%	0.061	19%	0.19	C	C	.	.	H	α-helix	trans	-64.8	-44.3	177.5	174.9	0	0	0	0	111.8	Y116 R345 M346 S351 R352 E353	Y116-V349 HydrophobicContact CD1-CG1 4.2Å; Y116-V349 HydrophobicContact CE1-CG1 4.28Å; R345-V349 WeakPolarHBondContact O-CG2 3.44Å; R345-V349 PolarHBondContact O-N 3.39Å; M346-V349 PolarHBondContact O-N 3.11Å; V349-S351 PolarHBondContact O-N 3.34Å; V349-R352 WeakPolarHBondContact O-CB 3.49Å; V349-R352 PolarHBondContact O-N 2.84Å; V349-E353 PolarHBondContact O-N 2.92Å
350	A	80	Confident	76.7	Confident	0 Å²	0	37 Å²	37	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-66.9	-35	-178.9	0	0	0	0	0	113.4	L132 M346 F347 E353 G354 Q355 L356	L132-A350 HydrophobicContact CD1-CB 3.68Å; L132-A350 HydrophobicContact CD2-CB 3.53Å; L132-A350 HydrophobicContact CG-CB 4.26Å; M346-A350 WeakPolarHBondContact O-CB 3.31Å; M346-A350 PolarHBondContact O-N 3.49Å; F347-A350 PolarHBondContact O-N 3.27Å; A350-E353 PolarHBondContact O-N 3.33Å; A350-G354 PolarHBondContact O-N 2.9Å; A350-Q355 PolarHBondContact O-N 2.95Å; A350-L356 HydrophobicContact CB-CD1 3.75Å; A350-L356 HydrophobicContact CB-CG 4.08Å; A350-L356 PolarHBondContact O-N 3.42Å
351	S	81.3	Confident	76.8	Confident	10 Å²	10	37.5 Å²	37.5	7%	0.07	19%	0.191	C	C	.	.	H	α-helix	trans	-66.5	-42.6	172.7	177.6	0	0	0	0	111.6	F347 V349 E353 G354 E358 S361	F347-S351 WeakPolarHBondContact O-CB 3.2Å; F347-S351 PolarHBondContact O-N 3.22Å; V349-S351 PolarHBondContact O-N 3.34Å; S351-E353 PolarHBondContact O-N 3.43Å; S351-G354 WeakPolarHBondContact O-CA 3.3Å; S351-G354 PolarHBondContact O-N 3.48Å; S351-E358 WeakPolarHBondContact OG-CA 3.49Å; S351-S361 WeakPolarHBondContact CB-OG 3.47Å; S351-S361 WeakPolarHBondContact OG-CB 3.32Å; S351-S361 PolarHBondContact OG-OG 3.07Å
352	R	78	Confident	77.1	Confident	122 Å²	122	36.3 Å²	36.3	46%	0.46	19%	0.186	S	C	.	.	H	α-helix	trans	-59.2	-32.3	175.8	-171	178.7	70.8	-175.2	0.9	112.8	E262 Y348 V349 G354	E262-R352 IonicContact OE1-NH2 2.87Å; Y348-R352 PolarHBondContact O-N 3.26Å; Y348-R352 VanDerWaalsContact O-N 3.09Å; V349-R352 WeakPolarHBondContact O-CB 3.49Å; V349-R352 PolarHBondContact O-N 2.84Å; R352-G354 PolarHBondContact O-N 3.39Å
353	E	80.9	Confident	77.3	Confident	79 Å²	79	38.2 Å²	38.2	37%	0.369	19%	0.194	S	C	.	.	T	Hydrogen-bonded Turn	trans	-84.7	7.6	175.1	-63.5	-69.3	162.2	0	0	113	Y116 V349 A350 S351 Q355	Y116-E353 HydrophobicContact CE1-CB 4.43Å; Y116-E353 HydrophobicContact CE1-CG 4.09Å; Y116-E353 WeakPolarHBondContact OH-CB 3.35Å; V349-E353 PolarHBondContact O-N 2.92Å; A350-E353 PolarHBondContact O-N 3.33Å; S351-E353 PolarHBondContact O-N 3.43Å; E353-Q355 VanDerWaalsContact C-N 3.27Å; E353-Q355 PolarHBondContact O-N 3.44Å
354	G	80.4	Confident	77.5	Confident	55 Å²	55	38.8 Å²	38.8	57%	0.567	20%	0.197	S	C	*	.	T	Hydrogen-bonded Turn	trans	70.6	17.8	176.5	0	0	0	0	0	114.6	A350 S351 R352	A350-G354 PolarHBondContact O-N 2.9Å; S351-G354 WeakPolarHBondContact O-CA 3.3Å; S351-G354 PolarHBondContact O-N 3.48Å; R352-G354 PolarHBondContact O-N 3.39Å
355	Q	83.8	Confident	77.7	Confident	10 Å²	10	41.6 Å²	41.6	5%	0.047	21%	0.213	C	C	.	.	S	Bend	trans	-98	-15.3	-176.7	-68.9	-154.9	-24.8	0	0	114.1	Y116 P125 F129 L132 A350 E353 I473	Y116-Q355 VanDerWaalsContact CZ-OE1 3.3Å; Y116-Q355 WeakPolarHBondContact OH-CG 3.36Å; Y116-Q355 PolarHBondContact OH-OE1 3.18Å; P125-Q355 PolarHBondContact O-NE2 2.71Å; F129-Q355 HydrophobicContact CD2-CB 4.14Å; F129-Q355 WeakPolarHBondContact CE2-O 3.24Å; L132-Q355 HydrophobicContact CD2-CB 4.09Å; A350-Q355 PolarHBondContact O-N 2.95Å; E353-Q355 VanDerWaalsContact C-N 3.27Å; E353-Q355 PolarHBondContact O-N 3.44Å; Q355-I473 HydrophobicContact CB-CD1 3.94Å; Q355-I473 HydrophobicContact CG-CD1 3.93Å
356	L	82.9	Confident	77.8	Confident	18 Å²	18	45.1 Å²	45.1	9%	0.094	23%	0.227	C	C	.	.	S	Bend	trans	-125.4	154.4	171.2	-73.5	178.3	0	0	0	110.3	L132 F347 A350 L360	L132-L356 HydrophobicContact CD1-CD1 4.17Å; L132-L356 HydrophobicContact CD2-CD1 4.33Å; L132-L356 HydrophobicContact CD2-CD2 4.47Å; L132-L356 HydrophobicContact CD2-CG 4.05Å; F347-L356 HydrophobicContact CB-CD1 4.28Å; F347-L356 HydrophobicContact CD1-CD1 3.95Å; F347-L356 HydrophobicContact CG-CD1 4.15Å; A350-L356 HydrophobicContact CB-CD1 3.75Å; A350-L356 HydrophobicContact CB-CG 4.08Å; A350-L356 PolarHBondContact O-N 3.42Å; L356-L360 HydrophobicContact CB-CD1 4.34Å; L356-L360 HydrophobicContact CD1-CD1 4.33Å; L356-L360 HydrophobicContact CD2-CD1 4.28Å
357	P	78.8	Confident	77.5	Confident	62 Å²	62	49.7 Å²	49.7	40%	0.403	24%	0.244	S	C	.	.			trans	-56.3	138.8	172.2	-23.5	33.2	0	0	0	111.8	V359 L360	P357-V359 PolarHBondContact O-N 3.35Å; P357-V359 VanDerWaalsContact O-N 3.09Å; P357-L360 WeakPolarHBondContact O-CB 3.5Å; P357-L360 PolarHBondContact O-N 3.1Å
358	E	75.7	Confident	77.1	Confident	120 Å²	120	56.5 Å²	56.5	56%	0.561	28%	0.275	S	S	*	.	G	3₁₀ helix	trans	-56.4	-32.9	-175.2	-69.8	-173.2	171.6	0	0	113.2	S351 L360 S361 M362	S351-E358 WeakPolarHBondContact OG-CA 3.49Å; E358-L360 PolarHBondContact O-N 3.14Å; E358-L360 VanDerWaalsContact O-N 3.12Å; E358-S361 PolarHBondContact O-N 2.99Å; E358-S361 PolarHBondContact O-OG 3.43Å; E358-M362 HydrophobicContact CB-CE 4.14Å; E358-M362 WeakPolarHBondContact O-CG 3.43Å; E358-M362 PolarHBondContact O-N 3.27Å
359	V	75.8	Confident	76.9	Confident	5 Å²	5	53 Å²	53	3%	0.03	26%	0.262	C	S	.	.	G	3₁₀ helix	trans	-54.7	-32.3	177.7	173.2	0	0	0	0	112.9	P357 S361 M362 A372 N490 M493	P357-V359 PolarHBondContact O-N 3.35Å; P357-V359 VanDerWaalsContact O-N 3.09Å; V359-S361 PolarHBondContact O-N 3.21Å; V359-M362 HydrophobicContact CG2-CE 3.9Å; V359-M362 HydrophobicContact CG2-SD 4.09Å; V359-M362 PolarHBondContact O-N 3.12Å; V359-A372 HydrophobicContact CG1-CB 3.95Å; V359-A372 VanDerWaalsContact O-CB 3.26Å; V359-A372 WeakPolarHBondContact O-CB 3.47Å; V359-N490 HydrophobicContact CG2-CB 3.6Å; V359-N490 WeakPolarHBondContact CG2-OD1 3.48Å; V359-M493 HydrophobicContact CG1-CB 3.86Å
360	L	76.6	Confident	76.8	Confident	18 Å²	18	54 Å²	54	9%	0.094	27%	0.268	C	S	.	.	G	3₁₀ helix	trans	-71.6	-16.2	179.5	-59.1	-173.4	0	0	0	113.6	F347 L356 P357 E358 A372 I376	F347-L360 HydrophobicContact CD2-CB 4.44Å; L356-L360 HydrophobicContact CB-CD1 4.34Å; L356-L360 HydrophobicContact CD1-CD1 4.33Å; L356-L360 HydrophobicContact CD2-CD1 4.28Å; P357-L360 WeakPolarHBondContact O-CB 3.5Å; P357-L360 PolarHBondContact O-N 3.1Å; E358-L360 PolarHBondContact O-N 3.14Å; E358-L360 VanDerWaalsContact O-N 3.12Å; L360-A372 HydrophobicContact CD2-CB 4.08Å; L360-I376 HydrophobicContact CD1-CD1 3.9Å; L360-I376 HydrophobicContact CD2-CD1 3.38Å; L360-I376 HydrophobicContact CD2-CG1 4.29Å; L360-I376 HydrophobicContact CG-CD1 4.3Å
361	S	74.9	Confident	76.5	Confident	20 Å²	20	54.8 Å²	54.8	14%	0.14	27%	0.272	C	S	.	.	G	3₁₀ helix	trans	-100.5	-6.4	173.7	63.1	0	0	0	0	114.2	S351 E358 V359	S351-S361 WeakPolarHBondContact CB-OG 3.47Å; S351-S361 WeakPolarHBondContact OG-CB 3.32Å; S351-S361 PolarHBondContact OG-OG 3.07Å; E358-S361 PolarHBondContact O-N 2.99Å; E358-S361 PolarHBondContact O-OG 3.43Å; V359-S361 PolarHBondContact O-N 3.21Å
362	M	77.1	Confident	76.1	Confident	8 Å²	8	54.6 Å²	54.6	4%	0.039	27%	0.271	C	S	.	.			trans	-72.6	151.1	-179.5	-64.2	-174.4	-171.6	0	0	111.7	E358 V359 Q494 V499 V500 P501	E358-M362 HydrophobicContact CB-CE 4.14Å; E358-M362 WeakPolarHBondContact O-CG 3.43Å; E358-M362 PolarHBondContact O-N 3.27Å; V359-M362 HydrophobicContact CG2-CE 3.9Å; V359-M362 HydrophobicContact CG2-SD 4.09Å; V359-M362 PolarHBondContact O-N 3.12Å; M362-Q494 HydrophobicContact SD-CG 3.97Å; M362-V499 HydrophobicContact CB-CB 3.73Å; M362-V499 HydrophobicContact CB-CG2 3.74Å; M362-V499 HydrophobicContact CG-CG2 4.45Å; M362-V499 HydrophobicContact SD-CG2 3.9Å; M362-V500 CarbonylContact C-O 3.4Å; M362-V500 VanDerWaalsContact CA-O 3.3Å; M362-V500 WeakPolarHBondContact CA-O 3.46Å; M362-V500 VanDerWaalsContact CB-O 3.29Å; M362-V500 WeakPolarHBondContact CB-O 3.46Å; M362-P501 HydrophobicContact CE-CG 4.17Å
363	I	75	Confident	75.9	Confident	54 Å²	54	48.8 Å²	48.8	28%	0.277	25%	0.25	S	C	.	.	E	Extended strand (participates in β ladder)	trans	-114.5	137.1	-175.1	-58.2	177.1	0	0	0	109	V365 H368 V499 V500 A502	I363-V365 PolarHBondContact O-N 3.41Å; I363-H368 VanDerWaalsContact CG2-CA 3.43Å; I363-H368 HydrophobicContact CG2-CB 4.27Å; I363-V499 CarbonylContact O-C 3.51Å; I363-V499 WeakPolarHBondContact O-CA 3.48Å; I363-V500 PolarHBondContact N-O 3.14Å; I363-V500 PolarHBondContact O-N 2.92Å; I363-A502 HydrophobicContact CD1-CB 3.82Å; I363-A502 HydrophobicContact CG1-CB 4.43Å
364	H	77.8	Confident	75.7	Confident	15 Å²	15	45.8 Å²	45.8	7%	0.069	24%	0.237	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-66	129.3	176.4	-173.7	-56.5	0	0	0	111.3	R366 R367 H368 T369 L497 E498 V499	H364-R366 PolarHBondContact ND1-N 3.23Å; H364-R366 VanDerWaalsContact ND1-N 3.19Å; H364-R366 PolarHBondContact O-N 2.96Å; H364-R367 PolarHBondContact O-N 2.83Å; H364-H368 WeakPolarHBondContact O-CA 3.48Å; H364-H368 PolarHBondContact O-N 3.47Å; H364-T369 WeakPolarHBondContact CB-O 3.32Å; H364-T369 PolarHBondContact N-O 3.28Å; H364-L497 PolarHBondContact CD2-O 3.41Å; H364-E498 IonicContact CE1-OE2 3.54Å; H364-V499 HydrophobicContact CB-CG1 4.28Å
365	V	76	Confident	75.6	Confident	75 Å²	75	47.2 Å²	47.2	46%	0.455	23%	0.231	S	C	.	.	T	Hydrogen-bonded Turn	trans	-57.5	-51.6	-171.5	177.4	0	0	0	0	112.9	I363 H368 E498 V500	I363-V365 PolarHBondContact O-N 3.41Å; V365-H368 PolarHBondContact O-CE1 3.35Å; V365-E498 WeakPolarHBondContact CG2-O 3.48Å; V365-E498 PolarHBondContact N-O 2.98Å; V365-V500 HydrophobicContact CG2-CB 4.27Å; V365-V500 HydrophobicContact CG2-CG1 3.54Å; V365-V500 HydrophobicContact CG2-CG2 3.8Å
366	R	74.1	Confident	75.5	Confident	184 Å²	184	49.8 Å²	49.8	69%	0.694	24%	0.244	S	C	*	.	T	Hydrogen-bonded Turn	trans	-78.4	-26.8	-174.9	-52.3	-174.4	-145.9	-158.6	2.8	114.9	H364 E498	H364-R366 PolarHBondContact ND1-N 3.23Å; H364-R366 VanDerWaalsContact ND1-N 3.19Å; H364-R366 PolarHBondContact O-N 2.96Å; R366-E498 IonicContact CZ-OE1 2.73Å; R366-E498 IonicContact CZ-OE2 2.81Å; R366-E498 IonicContact NE-OE2 2.96Å; R366-E498 PolarHBondContact NE-OE2 3.39Å; R366-E498 VanDerWaalsContact NH2-CD 3.33Å; R366-E498 IonicContact NH2-OE1 3.42Å; R366-E498 PolarHBondContact NH2-OE1 2.89Å; R366-E498 IonicContact NH2-OE2 3.19Å; R366-E498 PolarHBondContact NH2-OE2 2.98Å
367	R	68.8	Low	75.5	Confident	101 Å²	101	49 Å²	49	38%	0.381	24%	0.24	S	C	.	.	T	Hydrogen-bonded Turn	trans	-113.4	-13	-167.6	-56.1	-170.9	-175.8	157.4	8.2	113.3	I186 H364 T369	I186-R367 VanDerWaalsContact CG2-NH1 3.28Å; I186-R367 WeakPolarHBondContact O-CD 3.46Å; I186-R367 PolarHBondContact O-NH1 2.76Å; H364-R367 PolarHBondContact O-N 2.83Å; R367-T369 HydrophobicContact CB-CG2 3.78Å; R367-T369 WeakPolarHBondContact O-CG2 2.88Å; R367-T369 PolarHBondContact O-N 3.02Å
368	H	71.6	Confident	75.9	Confident	144 Å²	144	49.7 Å²	49.7	67%	0.667	24%	0.235	S	C	*	.			trans	55.2	38.8	-176.4	-54.5	-70.8	0	0	0	113.1	I363 H364 V365	I363-H368 VanDerWaalsContact CG2-CA 3.43Å; I363-H368 HydrophobicContact CG2-CB 4.27Å; H364-H368 WeakPolarHBondContact O-CA 3.48Å; H364-H368 PolarHBondContact O-N 3.47Å; V365-H368 PolarHBondContact O-CE1 3.35Å
369	T	70.2	Confident	76.5	Confident	3 Å²	3	47.4 Å²	47.4	2%	0.018	23%	0.231	C	C	.	.			trans	-116.2	145.2	-176.5	70.5	0	0	0	0	112	V189 H364 R367 L371	V189-T369 HydrophobicContact CB-CG2 3.99Å; V189-T369 HydrophobicContact CG2-CG2 3.21Å; H364-T369 WeakPolarHBondContact CB-O 3.32Å; H364-T369 PolarHBondContact N-O 3.28Å; R367-T369 HydrophobicContact CB-CG2 3.78Å; R367-T369 WeakPolarHBondContact O-CG2 2.88Å; R367-T369 PolarHBondContact O-N 3.02Å; T369-L371 VanDerWaalsContact C-N 3.29Å; T369-L371 PolarHBondContact O-N 3.44Å
370	P	72.3	Confident	77.1	Confident	30 Å²	30	50.4 Å²	50.4	20%	0.195	25%	0.246	C	C	.	.			trans	-81.8	70.7	178.9	32.4	-33.4	0	0	0	111	A372 A373 V374	P370-A372 PolarHBondContact O-N 3.15Å; P370-A373 HydrophobicContact CB-CB 4.42Å; P370-A373 PolarHBondContact O-N 2.92Å; P370-V374 WeakPolarHBondContact O-CG2 3.47Å; P370-V374 PolarHBondContact O-N 3.38Å
371	L	74.4	Confident	77.8	Confident	17 Å²	17	49.6 Å²	49.6	9%	0.089	24%	0.241	C	C	.	.	H	α-helix	trans	-61.5	-40	-170.8	-178.4	59.8	0	0	0	113.6	I186 T369 A373 V374 L375 L497 V499	I186-L371 HydrophobicContact CB-CD1 4.24Å; I186-L371 HydrophobicContact CD1-CD1 3.69Å; I186-L371 HydrophobicContact CG1-CD1 3.57Å; I186-L371 HydrophobicContact CG2-CD1 3.72Å; T369-L371 VanDerWaalsContact C-N 3.29Å; T369-L371 PolarHBondContact O-N 3.44Å; L371-A373 PolarHBondContact O-N 3.04Å; L371-V374 WeakPolarHBondContact O-CB 3.3Å; L371-V374 PolarHBondContact O-N 3.28Å; L371-L375 HydrophobicContact CD1-CG 4.42Å; L371-L375 HydrophobicContact CG-CD1 4.22Å; L371-L375 WeakPolarHBondContact O-CG 3.02Å; L371-L375 PolarHBondContact O-N 3.4Å; L371-L375 VanDerWaalsContact O-N 3.1Å; L371-L497 HydrophobicContact CD2-CB 4.09Å; L371-L497 HydrophobicContact CD2-CD2 3.77Å; L371-L497 HydrophobicContact CD2-CG 4.46Å; L371-L497 HydrophobicContact CG-CD2 4.2Å; L371-V499 HydrophobicContact CB-CG1 4.44Å
372	A	74.1	Confident	78.5	Confident	6 Å²	6	50.1 Å²	50.1	5%	0.05	24%	0.242	C	C	.	.	H	α-helix	trans	-64.9	-39.1	-177.2	0	0	0	0	0	112.7	V359 L360 P370 V374 L375 I376 L497	V359-A372 HydrophobicContact CG1-CB 3.95Å; V359-A372 VanDerWaalsContact O-CB 3.26Å; V359-A372 WeakPolarHBondContact O-CB 3.47Å; L360-A372 HydrophobicContact CD2-CB 4.08Å; P370-A372 PolarHBondContact O-N 3.15Å; A372-V374 VanDerWaalsContact C-N 3.3Å; A372-V374 PolarHBondContact O-N 2.88Å; A372-L375 PolarHBondContact O-N 3.26Å; A372-I376 PolarHBondContact O-N 3.44Å; A372-L497 HydrophobicContact CB-CD1 4.07Å
373	A	73.7	Confident	79.2	Confident	1 Å²	1	54.7 Å²	54.7	1%	0.008	27%	0.266	C	S	.	.	H	α-helix	trans	-59.7	-43	175.3	0	0	0	0	0	111.9	F347 P370 L371 I376 L377	F347-A373 HydrophobicContact CD2-CB 3.33Å; F347-A373 HydrophobicContact CE2-CB 3.69Å; F347-A373 HydrophobicContact CG-CB 4.4Å; P370-A373 HydrophobicContact CB-CB 4.42Å; P370-A373 PolarHBondContact O-N 2.92Å; L371-A373 PolarHBondContact O-N 3.04Å; A373-I376 PolarHBondContact O-N 3.15Å; A373-L377 PolarHBondContact O-N 3.34Å
374	V	76.3	Confident	79.9	Confident	15 Å²	15	52.9 Å²	52.9	9%	0.091	26%	0.256	C	S	.	.	H	α-helix	trans	-65.4	-41.2	-179	174.4	0	0	0	0	110.9	Y182 I186 P370 L371 A372 I376 L377 Y378	Y182-V374 HydrophobicContact CD1-CG1 3.23Å; Y182-V374 HydrophobicContact CE1-CB 4.42Å; Y182-V374 HydrophobicContact CE1-CG1 3.43Å; Y182-V374 VanDerWaalsContact CE1-CG1 3.43Å; Y182-V374 WeakPolarHBondContact CE1-O 3.48Å; Y182-V374 HydrophobicContact CG-CG1 4.44Å; I186-V374 HydrophobicContact CD1-CG1 4.01Å; I186-V374 HydrophobicContact CG1-CG1 4.02Å; P370-V374 WeakPolarHBondContact O-CG2 3.47Å; P370-V374 PolarHBondContact O-N 3.38Å; L371-V374 WeakPolarHBondContact O-CB 3.3Å; L371-V374 PolarHBondContact O-N 3.28Å; A372-V374 VanDerWaalsContact C-N 3.3Å; A372-V374 PolarHBondContact O-N 2.88Å; V374-I376 VanDerWaalsContact C-N 3.32Å; V374-I376 PolarHBondContact O-N 3.36Å; V374-L377 PolarHBondContact O-N 3.19Å; V374-Y378 PolarHBondContact O-N 2.98Å
375	L	78.7	Confident	80.4	Confident	85 Å²	85	52.1 Å²	52.1	45%	0.445	25%	0.253	S	S	.	.	H	α-helix	trans	-65.9	-29.7	-179.5	-73.5	173.4	0	0	0	114.1	L371 A372 P379 L497	L371-L375 HydrophobicContact CD1-CG 4.42Å; L371-L375 HydrophobicContact CG-CD1 4.22Å; L371-L375 WeakPolarHBondContact O-CG 3.02Å; L371-L375 PolarHBondContact O-N 3.4Å; L371-L375 VanDerWaalsContact O-N 3.1Å; A372-L375 PolarHBondContact O-N 3.26Å; L375-P379 WeakPolarHBondContact O-CD 3.39Å; L375-P379 WeakPolarHBondContact O-CG 3.48Å; L375-L497 HydrophobicContact CD1-CD1 4.04Å; L375-L497 HydrophobicContact CD1-CD2 3.43Å; L375-L497 VanDerWaalsContact CD1-CD2 3.43Å; L375-L497 HydrophobicContact CD1-CG 4.4Å
376	I	81.2	Confident	81	Confident	65 Å²	65	52.9 Å²	52.9	33%	0.333	25%	0.251	S	S	.	.	H	α-helix	trans	-77.6	-38.4	174.7	-66.5	-172.5	0	0	0	111.1	L136 L360 A372 A373 V374 P379 M380	L136-I376 HydrophobicContact CD1-CG2 4.42Å; L360-I376 HydrophobicContact CD1-CD1 3.9Å; L360-I376 HydrophobicContact CD2-CD1 3.38Å; L360-I376 HydrophobicContact CD2-CG1 4.29Å; L360-I376 HydrophobicContact CG-CD1 4.3Å; A372-I376 PolarHBondContact O-N 3.44Å; A373-I376 PolarHBondContact O-N 3.15Å; V374-I376 VanDerWaalsContact C-N 3.32Å; V374-I376 PolarHBondContact O-N 3.36Å; I376-P379 WeakPolarHBondContact O-CD 3.48Å; I376-M380 WeakPolarHBondContact O-CG 3.31Å
377	L	81.8	Confident	81.5	Confident	2 Å²	2	49.8 Å²	49.8	1%	0.01	25%	0.252	C	S	.	.	H	α-helix	trans	-75.3	-35.9	-173.9	-168.7	72.2	0	0	0	112.8	R140 P141 L144 Y182 L343 A373 V374 M380 T381	R140-L377 HydrophobicContact CB-CD1 4.38Å; P141-L377 HydrophobicContact CG-CD1 3.94Å; L144-L377 HydrophobicContact CD1-CD1 4.48Å; L144-L377 HydrophobicContact CD1-CD2 3.3Å; L144-L377 HydrophobicContact CD1-CG 4.04Å; Y182-L377 WeakPolarHBondContact OH-CD2 3.41Å; Y182-L377 WeakPolarHBondContact OH-CG 3.41Å; L343-L377 HydrophobicContact CD1-CD1 3.89Å; L343-L377 HydrophobicContact CD1-CD2 4.34Å; L343-L377 HydrophobicContact CD2-CB 4.19Å; L343-L377 HydrophobicContact CD2-CD1 4.09Å; L343-L377 HydrophobicContact CD2-CD2 3.63Å; L343-L377 HydrophobicContact CD2-CG 4.18Å; L343-L377 HydrophobicContact CG-CD2 4.44Å; A373-L377 PolarHBondContact O-N 3.34Å; V374-L377 PolarHBondContact O-N 3.19Å; L377-M380 PolarHBondContact O-N 3.27Å; L377-T381 WeakPolarHBondContact O-CB 3.45Å; L377-T381 PolarHBondContact O-N 2.61Å; L377-T381 PolarHBondContact O-OG1 3.22Å
378	Y	87.1	Confident	81.8	Confident	75 Å²	75	45.5 Å²	45.5	29%	0.294	24%	0.239	S	C	.	.	H	α-helix	trans	-57.8	-54.2	-176.2	178.6	-110	0	0	0	112.8	I178 S179 Y182 V374 M380 T381 I382	I178-Y378 HydrophobicContact CG2-CE2 4.41Å; S179-Y378 PolarHBondContact OG-OH 2.87Å; Y182-Y378 AromaticContact CD1-CD2 3.79Å; Y182-Y378 HydrophobicContact CD1-CD2 3.79Å; Y182-Y378 HydrophobicContact CD1-CG 4.03Å; Y182-Y378 AromaticContact CD2-CD2 3.51Å; Y182-Y378 HydrophobicContact CD2-CD2 3.51Å; Y182-Y378 HydrophobicContact CD2-CE2 4.12Å; Y182-Y378 HydrophobicContact CD2-CG 4.49Å; Y182-Y378 AromaticContact CE1-CD2 3.97Å; Y182-Y378 HydrophobicContact CE1-CD2 3.97Å; Y182-Y378 HydrophobicContact CE1-CG 4.09Å; Y182-Y378 AromaticContact CE2-CD2 3.61Å; Y182-Y378 HydrophobicContact CE2-CD2 3.61Å; Y182-Y378 HydrophobicContact CE2-CE2 4.48Å; Y182-Y378 HydrophobicContact CE2-CG 4.47Å; Y182-Y378 AromaticContact CG-CD2 3.55Å; Y182-Y378 HydrophobicContact CG-CD2 3.55Å; Y182-Y378 HydrophobicContact CG-CE2 4.25Å; Y182-Y378 HydrophobicContact CG-CG 4.23Å; Y182-Y378 AromaticContact CZ-CD2 3.82Å; Y182-Y378 WeakPolarHBondContact OH-CA 3.49Å; Y182-Y378 PolarHBondContact OH-N 3.45Å; V374-Y378 PolarHBondContact O-N 2.98Å; Y378-M380 VanDerWaalsContact C-N 3.3Å; Y378-M380 PolarHBondContact O-N 2.95Å; Y378-T381 PolarHBondContact O-N 2.73Å; Y378-I382 HydrophobicContact CD2-CG1 4.12Å; Y378-I382 HydrophobicContact CE1-CG1 4.1Å; Y378-I382 HydrophobicContact CE2-CD1 3.9Å; Y378-I382 HydrophobicContact CE2-CG1 3.66Å; Y378-I382 WeakPolarHBondContact O-CG1 3.31Å; Y378-I382 PolarHBondContact O-N 3.15Å
379	P	89.4	Confident	82.2	Confident	72 Å²	72	42 Å²	42	47%	0.468	23%	0.225	S	C	.	.	H	α-helix	trans	-62.9	-38.2	-179.9	-20.7	34.4	0	0	0	112.1	L375 I376 T381 I382 L383	L375-P379 WeakPolarHBondContact O-CD 3.39Å; L375-P379 WeakPolarHBondContact O-CG 3.48Å; I376-P379 WeakPolarHBondContact O-CD 3.48Å; P379-T381 VanDerWaalsContact C-N 3.34Å; P379-T381 PolarHBondContact O-N 3.18Å; P379-I382 PolarHBondContact O-N 3.44Å; P379-L383 VanDerWaalsContact O-CB 3.31Å; P379-L383 WeakPolarHBondContact O-CB 3.2Å; P379-L383 PolarHBondContact O-N 3.4Å
380	M	88.9	Confident	82.5	Confident	69 Å²	69	43.6 Å²	43.6	34%	0.34	23%	0.233	S	C	.	.	H	α-helix	trans	-62.9	-41.2	177.5	-67.3	-65.3	-176.8	0	0	111.7	P141 I376 L377 Y378 L383 Q384	P141-M380 HydrophobicContact CB-CB 3.99Å; P141-M380 HydrophobicContact CG-CB 3.81Å; I376-M380 WeakPolarHBondContact O-CG 3.31Å; L377-M380 PolarHBondContact O-N 3.27Å; Y378-M380 VanDerWaalsContact C-N 3.3Å; Y378-M380 PolarHBondContact O-N 2.95Å; M380-L383 PolarHBondContact O-N 3.42Å; M380-Q384 WeakPolarHBondContact O-CG 3.48Å; M380-Q384 PolarHBondContact O-N 3.22Å; M380-Q384 VanDerWaalsContact O-N 3.08Å
381	T	89.8	Confident	82.7	Confident	0 Å²	0	48.6 Å²	48.6	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-70.3	-41.4	179.4	-51.7	0	0	0	0	111.2	L144 A145 I178 L377 Y378 P379 Q384 L385	L144-T381 HydrophobicContact CB-CG2 3.74Å; A145-T381 HydrophobicContact CB-CG2 4.17Å; I178-T381 HydrophobicContact CD1-CG2 3.37Å; L377-T381 WeakPolarHBondContact O-CB 3.45Å; L377-T381 PolarHBondContact O-N 2.61Å; L377-T381 PolarHBondContact O-OG1 3.22Å; Y378-T381 PolarHBondContact O-N 2.73Å; P379-T381 VanDerWaalsContact C-N 3.34Å; P379-T381 PolarHBondContact O-N 3.18Å; T381-Q384 PolarHBondContact O-N 3.1Å; T381-L385 VanDerWaalsContact O-CB 3.28Å; T381-L385 WeakPolarHBondContact O-CB 3.45Å; T381-L385 PolarHBondContact O-N 3.25Å
382	I	91.3	Very high	83.2	Confident	32 Å²	32	49.3 Å²	49.3	16%	0.164	26%	0.255	C	S	.	.	H	α-helix	trans	-62.3	-44.3	174.5	-70	-65.7	0	0	0	111.1	A175 I178 Y378 P379 Q384 L385 F386	A175-I382 HydrophobicContact CB-CD1 4.4Å; I178-I382 HydrophobicContact CG2-CD1 3.66Å; Y378-I382 HydrophobicContact CD2-CG1 4.12Å; Y378-I382 HydrophobicContact CE1-CG1 4.1Å; Y378-I382 HydrophobicContact CE2-CD1 3.9Å; Y378-I382 HydrophobicContact CE2-CG1 3.66Å; Y378-I382 WeakPolarHBondContact O-CG1 3.31Å; Y378-I382 PolarHBondContact O-N 3.15Å; P379-I382 PolarHBondContact O-N 3.44Å; I382-Q384 PolarHBondContact O-N 3.23Å; I382-L385 WeakPolarHBondContact O-CB 3.35Å; I382-L385 PolarHBondContact O-N 2.95Å; I382-F386 HydrophobicContact CG2-CD2 3.88Å; I382-F386 HydrophobicContact CG2-CE2 3.85Å; I382-F386 VanDerWaalsContact O-CD2 3.26Å; I382-F386 WeakPolarHBondContact O-CD2 3.32Å; I382-F386 PolarHBondContact O-N 2.95Å; I382-F386 VanDerWaalsContact O-N 3.14Å
383	L	91.1	Very high	83.7	Confident	103 Å²	103	49.5 Å²	49.5	54%	0.539	26%	0.255	S	S	.	.	H	α-helix	trans	-58.3	-50.1	177.5	-176.2	153.6	0	0	0	110.7	P379 M380 L385 F386 V387	P379-L383 VanDerWaalsContact O-CB 3.31Å; P379-L383 WeakPolarHBondContact O-CB 3.2Å; P379-L383 PolarHBondContact O-N 3.4Å; M380-L383 PolarHBondContact O-N 3.42Å; L383-L385 VanDerWaalsContact C-N 3.33Å; L383-L385 PolarHBondContact O-N 2.95Å; L383-F386 PolarHBondContact O-N 2.93Å; L383-V387 HydrophobicContact CD2-CG2 3.94Å; L383-V387 HydrophobicContact CG-CG2 4.43Å; L383-V387 VanDerWaalsContact O-CG2 3.27Å; L383-V387 WeakPolarHBondContact O-CG2 3.31Å; L383-V387 PolarHBondContact O-N 3.22Å
384	Q	88.6	Confident	84	Confident	16 Å²	16	50 Å²	50	8%	0.075	26%	0.257	C	S	.	.	H	α-helix	trans	-66.7	-34	-179.8	-70.5	-170.3	12.5	0	0	113.2	I137 P141 A145 M380 T381 I382 F386 V387 G388 L393	I137-Q384 PolarHBondContact O-NE2 3.26Å; P141-Q384 VanDerWaalsContact C-OE1 3.3Å; A145-Q384 HydrophobicContact CB-CB 4.42Å; M380-Q384 WeakPolarHBondContact O-CG 3.48Å; M380-Q384 PolarHBondContact O-N 3.22Å; M380-Q384 VanDerWaalsContact O-N 3.08Å; T381-Q384 PolarHBondContact O-N 3.1Å; I382-Q384 PolarHBondContact O-N 3.23Å; Q384-F386 VanDerWaalsContact C-N 3.29Å; Q384-F386 PolarHBondContact O-N 2.95Å; Q384-V387 PolarHBondContact O-N 2.84Å; Q384-G388 PolarHBondContact O-N 3.29Å; Q384-L393 HydrophobicContact CB-CD2 4.14Å
385	L	90.2	Very high	84.4	Confident	0 Å²	0	50.8 Å²	50.8	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-58.9	-39.3	173.1	172.5	155.4	0	0	0	112.3	A145 L149 K171 T174 T381 I382 L383	A145-L385 HydrophobicContact CB-CB 4.32Å; L149-L385 HydrophobicContact CD2-CG 4.29Å; K171-L385 HydrophobicContact CB-CD2 4.19Å; K171-L385 VanDerWaalsContact CE-O 3.29Å; K171-L385 WeakPolarHBondContact CE-O 3.48Å; K171-L385 HydrophobicContact CG-CD2 4.39Å; T174-L385 HydrophobicContact CG2-CD1 3.32Å; T174-L385 HydrophobicContact CG2-CG 4.47Å; T381-L385 VanDerWaalsContact O-CB 3.28Å; T381-L385 WeakPolarHBondContact O-CB 3.45Å; T381-L385 PolarHBondContact O-N 3.25Å; I382-L385 WeakPolarHBondContact O-CB 3.35Å; I382-L385 PolarHBondContact O-N 2.95Å; L383-L385 VanDerWaalsContact C-N 3.33Å; L383-L385 PolarHBondContact O-N 2.95Å
386	F	88.2	Confident	84.7	Confident	91 Å²	91	47.5 Å²	47.5	40%	0.399	24%	0.244	S	C	.	.	H	α-helix	trans	-81.3	-37	179.5	-78.4	-69.9	0	0	0	112.8	K171 A175 I382 L383 Q384	K171-F386 HydrophobicContact CB-CE1 4.28Å; K171-F386 HydrophobicContact CD-CD1 4.32Å; K171-F386 PolarHBondContact NZ-O 3.47Å; A175-F386 HydrophobicContact CB-CZ 4.4Å; I382-F386 HydrophobicContact CG2-CD2 3.88Å; I382-F386 HydrophobicContact CG2-CE2 3.85Å; I382-F386 VanDerWaalsContact O-CD2 3.26Å; I382-F386 WeakPolarHBondContact O-CD2 3.32Å; I382-F386 PolarHBondContact O-N 2.95Å; I382-F386 VanDerWaalsContact O-N 3.14Å; L383-F386 PolarHBondContact O-N 2.93Å; Q384-F386 VanDerWaalsContact C-N 3.29Å; Q384-F386 PolarHBondContact O-N 2.95Å
387	V	84.1	Confident	85	Confident	119 Å²	119	44.8 Å²	44.8	72%	0.721	23%	0.23	S	C	*	.	H	α-helix	trans	-71	-43.7	-178.6	172.5	0	0	0	0	112.1	L383 Q384	L383-V387 HydrophobicContact CD2-CG2 3.94Å; L383-V387 HydrophobicContact CG-CG2 4.43Å; L383-V387 VanDerWaalsContact O-CG2 3.27Å; L383-V387 WeakPolarHBondContact O-CG2 3.31Å; L383-V387 PolarHBondContact O-N 3.22Å; Q384-V387 PolarHBondContact O-N 2.84Å
388	G	74.8	Confident	85.3	Confident	10 Å²	10	44.8 Å²	44.8	10%	0.103	23%	0.23	C	C	.	.			trans	-98.9	163.1	-172.2	0	0	0	0	0	114.8	K171 Q384	K171-G388 WeakPolarHBondContact CE-O 3.37Å; K171-G388 PolarHBondContact NZ-O 3.32Å; K171-G388 VanDerWaalsContact NZ-O 3.14Å; Q384-G388 PolarHBondContact O-N 3.29Å
389	D	79.6	Confident	85.5	Confident	72 Å²	72	41.8 Å²	41.8	39%	0.385	22%	0.218	S	C	.	.			trans	-97.5	169.1	155.4	71.6	-63	0	0	0	110.1	Y391 S392 L393	D389-Y391 VanDerWaalsContact C-N 3.31Å; D389-Y391 PolarHBondContact O-N 3.4Å; D389-Y391 PolarHBondContact OD2-N 2.9Å; D389-Y391 VanDerWaalsContact OD2-N 3.13Å; D389-S392 PolarHBondContact O-N 3.49Å; D389-S392 WeakPolarHBondContact OD1-CB 3.39Å; D389-S392 PolarHBondContact OD1-N 3.15Å; D389-S392 PolarHBondContact OD1-OG 3.01Å; D389-S392 PolarHBondContact OD2-N 3.29Å; D389-L393 WeakPolarHBondContact O-CB 3.35Å; D389-L393 VanDerWaalsContact O-CG 3.29Å; D389-L393 WeakPolarHBondContact O-CG 3.47Å; D389-L393 PolarHBondContact O-N 3.19Å
390	I	76.6	Confident	85.6	Confident	35 Å²	35	38.3 Å²	38.3	18%	0.179	20%	0.196	C	C	.	.	H	α-helix	trans	-56.8	-45	-175.8	-63	175.6	0	0	0	111.2	V146 L149 L394	V146-I390 HydrophobicContact CG1-CG2 4.38Å; L149-I390 HydrophobicContact CB-CD1 3.91Å; L149-I390 HydrophobicContact CB-CG1 3.67Å; L149-I390 HydrophobicContact CD1-CG1 3.8Å; L149-I390 HydrophobicContact CG-CG1 4.33Å; I390-L394 HydrophobicContact CG2-CD1 3.93Å; I390-L394 HydrophobicContact CG2-CG 4.45Å; I390-L394 WeakPolarHBondContact O-CB 3.49Å; I390-L394 WeakPolarHBondContact O-CG 3.19Å; I390-L394 PolarHBondContact O-N 2.82Å
391	Y	77.5	Confident	85.7	Confident	136 Å²	136	36.6 Å²	36.6	53%	0.533	19%	0.185	S	C	.	.	H	α-helix	trans	-76	-40	-173.8	-68.9	-78	0	0	0	112.3	D389 L394 N395	D389-Y391 VanDerWaalsContact C-N 3.31Å; D389-Y391 PolarHBondContact O-N 3.4Å; D389-Y391 PolarHBondContact OD2-N 2.9Å; D389-Y391 VanDerWaalsContact OD2-N 3.13Å; Y391-L394 HydrophobicContact CD1-CD1 4.36Å; Y391-L394 WeakPolarHBondContact O-CB 3.5Å; Y391-L394 PolarHBondContact O-N 2.94Å; Y391-N395 PolarHBondContact O-N 3.13Å
392	S	83.8	Confident	85.8	Confident	31 Å²	31	36.7 Å²	36.7	22%	0.217	19%	0.186	C	C	.	.	H	α-helix	trans	-63.9	-41.4	174	-58.4	0	0	0	0	111.8	D389 L394 N395 F396 N454	D389-S392 PolarHBondContact O-N 3.49Å; D389-S392 WeakPolarHBondContact OD1-CB 3.39Å; D389-S392 PolarHBondContact OD1-N 3.15Å; D389-S392 PolarHBondContact OD1-OG 3.01Å; D389-S392 PolarHBondContact OD2-N 3.29Å; S392-L394 VanDerWaalsContact C-N 3.33Å; S392-L394 PolarHBondContact O-N 2.98Å; S392-N395 PolarHBondContact O-N 2.85Å; S392-F396 WeakPolarHBondContact O-CB 3.34Å; S392-F396 PolarHBondContact O-N 3.44Å; S392-N454 WeakPolarHBondContact CB-ND2 3.2Å
393	L	84.4	Confident	85.9	Confident	10 Å²	10	36.5 Å²	36.5	5%	0.052	19%	0.185	C	C	.	.	H	α-helix	trans	-64.4	-38.4	175.8	-71.4	171.1	0	0	0	111.9	A142 A145 V146 L149 Q384 D389 M397	A142-L393 HydrophobicContact CB-CD2 4.49Å; A145-L393 HydrophobicContact CB-CD1 4.01Å; V146-L393 HydrophobicContact CG2-CB 3.55Å; V146-L393 HydrophobicContact CG2-CD1 4.45Å; L149-L393 HydrophobicContact CD1-CD1 3.96Å; Q384-L393 HydrophobicContact CB-CD2 4.14Å; D389-L393 WeakPolarHBondContact O-CB 3.35Å; D389-L393 VanDerWaalsContact O-CG 3.29Å; D389-L393 WeakPolarHBondContact O-CG 3.47Å; D389-L393 PolarHBondContact O-N 3.19Å; L393-M397 WeakPolarHBondContact O-CB 3.41Å; L393-M397 WeakPolarHBondContact O-CG 3.33Å; L393-M397 PolarHBondContact O-N 3.49Å
394	L	81.4	Confident	86.1	Confident	11 Å²	11	31.9 Å²	31.9	6%	0.058	16%	0.161	C	C	.	.	H	α-helix	trans	-60.1	-44.8	172.9	-79.8	172.3	0	0	0	111.8	V146 Y245 Y249 I390 Y391 S392 M397 S398	V146-L394 HydrophobicContact CG1-CD2 3.68Å; V146-L394 HydrophobicContact CG1-CG 3.97Å; V146-L394 HydrophobicContact CG2-CD2 4.22Å; V146-L394 HydrophobicContact CG2-CG 4.09Å; Y245-L394 PolarHBondContact OH-O 2.86Å; Y249-L394 HydrophobicContact CD2-CD2 3.83Å; Y249-L394 HydrophobicContact CE1-CD2 4Å; Y249-L394 HydrophobicContact CE2-CD2 3.23Å; Y249-L394 HydrophobicContact CG-CD2 4.5Å; Y249-L394 WeakPolarHBondContact OH-CD2 3.22Å; I390-L394 HydrophobicContact CG2-CD1 3.93Å; I390-L394 HydrophobicContact CG2-CG 4.45Å; I390-L394 WeakPolarHBondContact O-CB 3.49Å; I390-L394 WeakPolarHBondContact O-CG 3.19Å; I390-L394 PolarHBondContact O-N 2.82Å; Y391-L394 HydrophobicContact CD1-CD1 4.36Å; Y391-L394 WeakPolarHBondContact O-CB 3.5Å; Y391-L394 PolarHBondContact O-N 2.94Å; S392-L394 VanDerWaalsContact C-N 3.33Å; S392-L394 PolarHBondContact O-N 2.98Å; L394-M397 HydrophobicContact CD2-CE 3.84Å; L394-M397 WeakPolarHBondContact O-CG 3.46Å; L394-S398 WeakPolarHBondContact O-CB 3.16Å; L394-S398 PolarHBondContact O-N 2.89Å; L394-S398 PolarHBondContact O-OG 3.24Å
395	N	83.6	Confident	86.4	Confident	32 Å²	32	31.3 Å²	31.3	17%	0.171	16%	0.158	C	C	.	.	H	α-helix	trans	-65.8	-48.9	176.9	-71.9	-18.1	0	0	0	112.6	Y245 Y391 S392 M397 S398 F399 D451	Y245-N395 VanDerWaalsContact CE1-OD1 3.28Å; Y245-N395 WeakPolarHBondContact CE1-OD1 3.19Å; Y245-N395 VanDerWaalsContact OH-CA 3.24Å; Y245-N395 WeakPolarHBondContact OH-CA 3.46Å; Y245-N395 PolarHBondContact OH-OD1 3.39Å; Y391-N395 PolarHBondContact O-N 3.13Å; S392-N395 PolarHBondContact O-N 2.85Å; N395-M397 PolarHBondContact O-N 3.28Å; N395-S398 PolarHBondContact O-N 3.34Å; N395-F399 PolarHBondContact O-N 2.85Å; N395-F399 VanDerWaalsContact O-N 3.08Å; N395-D451 HydrophobicContact CB-CB 4.31Å
396	F	86.1	Confident	86.6	Confident	17 Å²	17	31.3 Å²	31.3	8%	0.075	16%	0.158	C	C	.	.	H	α-helix	trans	-52.3	-52.1	175.8	174.1	-97.9	0	0	0	112.1	A138 A142 S392 N454 V457 M461	A138-F396 HydrophobicContact CB-CE1 3.65Å; A138-F396 HydrophobicContact CB-CZ 3.57Å; A142-F396 HydrophobicContact CB-CD1 3.92Å; A142-F396 HydrophobicContact CB-CE1 4.2Å; S392-F396 WeakPolarHBondContact O-CB 3.34Å; S392-F396 PolarHBondContact O-N 3.44Å; F396-N454 HydrophobicContact CB-CB 4.48Å; F396-N454 WeakPolarHBondContact CD2-O 3.31Å; F396-V457 HydrophobicContact CE2-CG1 4.45Å; F396-M461 HydrophobicContact CE2-SD 4.05Å; F396-M461 HydrophobicContact CZ-SD 3.84Å
397	M	87.2	Confident	87	Confident	8 Å²	8	28 Å²	28	4%	0.039	15%	0.145	C	C	.	.	H	α-helix	trans	-74.8	-36.3	-177.7	79.7	179.2	-151.7	0	0	112.7	A142 A143 V146 Y249 L393 L394 N395 L400 R401	A142-M397 HydrophobicContact CB-CB 3.7Å; A142-M397 HydrophobicContact CB-SD 4.44Å; A143-M397 VanDerWaalsContact CA-SD 3.51Å; A143-M397 HydrophobicContact CB-SD 3.87Å; V146-M397 HydrophobicContact CG2-SD 4.35Å; Y249-M397 HydrophobicContact CD2-CE 4.17Å; Y249-M397 HydrophobicContact CE2-CE 3.47Å; Y249-M397 VanDerWaalsContact CE2-CE 3.47Å; L393-M397 WeakPolarHBondContact O-CB 3.41Å; L393-M397 WeakPolarHBondContact O-CG 3.33Å; L393-M397 PolarHBondContact O-N 3.49Å; L394-M397 HydrophobicContact CD2-CE 3.84Å; L394-M397 WeakPolarHBondContact O-CG 3.46Å; N395-M397 PolarHBondContact O-N 3.28Å; M397-L400 PolarHBondContact O-N 3.4Å; M397-R401 WeakPolarHBondContact O-CB 3.39Å; M397-R401 PolarHBondContact O-N 3.47Å
398	S	87.6	Confident	87.6	Confident	1 Å²	1	22.4 Å²	22.4	1%	0.007	11%	0.111	C	C	.	.	H	α-helix	trans	-68.3	-38.8	-175.4	-68.1	0	0	0	0	111.4	Y245 L394 N395 R401 W402	Y245-S398 WeakPolarHBondContact OH-CB 3.46Å; Y245-S398 PolarHBondContact OH-OG 2.99Å; L394-S398 WeakPolarHBondContact O-CB 3.16Å; L394-S398 PolarHBondContact O-N 2.89Å; L394-S398 PolarHBondContact O-OG 3.24Å; N395-S398 PolarHBondContact O-N 3.34Å; S398-R401 PolarHBondContact O-N 3.14Å; S398-R401 PolarHBondContact OG-NH2 2.91Å; S398-W402 WeakPolarHBondContact O-CB 3.43Å; S398-W402 PolarHBondContact O-N 3.08Å
399	F	90.4	Very high	88.6	Confident	12 Å²	12	22 Å²	22	5%	0.053	11%	0.106	C	C	.	.	H	α-helix	trans	-53.8	-57.1	173.9	168.7	-93.9	0	0	0	111.4	N395 R401 W402 L403 V444 T455 F459	N395-F399 PolarHBondContact O-N 2.85Å; N395-F399 VanDerWaalsContact O-N 3.08Å; F399-R401 VanDerWaalsContact C-N 3.32Å; F399-R401 PolarHBondContact O-N 3.44Å; F399-W402 PolarHBondContact O-N 3.49Å; F399-L403 HydrophobicContact CE1-CD2 4.37Å; F399-L403 WeakPolarHBondContact O-CB 3.12Å; F399-L403 PolarHBondContact O-N 3.34Å; F399-V444 HydrophobicContact CD2-CG1 3.9Å; F399-V444 HydrophobicContact CE2-CG1 3.46Å; F399-V444 VanDerWaalsContact CE2-CG1 3.46Å; F399-V444 HydrophobicContact CZ-CG1 4.23Å; F399-T455 HydrophobicContact CB-CG2 3.61Å; F399-T455 HydrophobicContact CD2-CG2 4.03Å; F399-T455 HydrophobicContact CG-CG2 3.85Å; F399-F459 HydrophobicContact CE1-CB 3.74Å; F399-F459 HydrophobicContact CE1-CD2 4.03Å; F399-F459 HydrophobicContact CE1-CG 4.26Å; F399-F459 HydrophobicContact CZ-CB 4.08Å; F399-F459 HydrophobicContact CZ-CD2 4.13Å; F399-F459 HydrophobicContact CZ-CG 4.31Å
400	L	91.9	Very high	89.5	Confident	0 Å²	0	22 Å²	22	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-63.8	-40.3	-178.4	-73	177.3	0	0	0	111.6	A138 I139 M397 L403 F404	A138-L400 HydrophobicContact CB-CD1 3.41Å; A138-L400 VanDerWaalsContact CB-CD1 3.41Å; I139-L400 HydrophobicContact CD1-CB 3.84Å; I139-L400 HydrophobicContact CG1-CB 3.66Å; I139-L400 HydrophobicContact CG1-CD1 4.1Å; M397-L400 PolarHBondContact O-N 3.4Å; L400-L403 PolarHBondContact O-N 2.78Å; L400-F404 HydrophobicContact CD2-CE2 4.45Å; L400-F404 WeakPolarHBondContact O-CD2 3.37Å; L400-F404 PolarHBondContact O-N 3.47Å
401	R	91	Very high	90.4	Very high	32 Å²	32	20.4 Å²	20.4	12%	0.121	10%	0.098	C	C	.	.	H	α-helix	trans	-60.8	-50.2	177.9	-178.3	178	62.7	168.6	2.5	111.6	M397 S398 F399 L403 F404 I405	M397-R401 WeakPolarHBondContact O-CB 3.39Å; M397-R401 PolarHBondContact O-N 3.47Å; S398-R401 PolarHBondContact O-N 3.14Å; S398-R401 PolarHBondContact OG-NH2 2.91Å; F399-R401 VanDerWaalsContact C-N 3.32Å; F399-R401 PolarHBondContact O-N 3.44Å; R401-L403 VanDerWaalsContact C-N 3.34Å; R401-F404 PolarHBondContact O-N 3.42Å; R401-I405 HydrophobicContact CG-CD1 3.79Å; R401-I405 WeakPolarHBondContact O-CB 3.04Å; R401-I405 VanDerWaalsContact O-CG1 3.24Å; R401-I405 WeakPolarHBondContact O-CG1 3.08Å; R401-I405 PolarHBondContact O-N 3.21Å
402	W	92.2	Very high	91.2	Very high	3 Å²	3	14 Å²	14	1%	0.011	7%	0.074	C	C	.	.	H	α-helix	trans	-65.8	-37.4	179	-72.9	121.7	0	0	0	112.2	M248 S398 F399 I405 G406 F436 M443 V444	M248-W402 HydrophobicContact CB-CH2 3.97Å; M248-W402 HydrophobicContact CB-CZ2 3.55Å; M248-W402 HydrophobicContact CE-CH2 3.49Å; M248-W402 VanDerWaalsContact CE-CH2 3.49Å; M248-W402 HydrophobicContact CE-CZ2 4.27Å; M248-W402 HydrophobicContact CE-CZ3 3.99Å; S398-W402 WeakPolarHBondContact O-CB 3.43Å; S398-W402 PolarHBondContact O-N 3.08Å; F399-W402 PolarHBondContact O-N 3.49Å; W402-I405 HydrophobicContact CE3-CD1 4.43Å; W402-I405 HydrophobicContact CZ3-CD1 4.45Å; W402-I405 PolarHBondContact O-N 3.36Å; W402-G406 PolarHBondContact O-N 2.68Å; W402-F436 HydrophobicContact CZ3-CE2 4.45Å; W402-F436 HydrophobicContact CZ3-CZ 4.1Å; W402-M443 HydrophobicContact CB-CB 4.15Å; W402-M443 HydrophobicContact CD2-CB 4.18Å; W402-M443 HydrophobicContact CD2-CG 4.39Å; W402-M443 HydrophobicContact CG-CB 3.8Å; W402-M443 HydrophobicContact CG-CG 4.49Å; W402-V444 HydrophobicContact CB-CG2 3.93Å
403	L	94.1	Very high	91.8	Very high	27 Å²	27	13.7 Å²	13.7	14%	0.141	7%	0.069	C	C	.	.	H	α-helix	trans	-57.1	-54	174.6	179.9	66	0	0	0	110.9	F399 L400 R401 G406 V407 F441 V444 F459	F399-L403 HydrophobicContact CE1-CD2 4.37Å; F399-L403 WeakPolarHBondContact O-CB 3.12Å; F399-L403 PolarHBondContact O-N 3.34Å; L400-L403 PolarHBondContact O-N 2.78Å; R401-L403 VanDerWaalsContact C-N 3.34Å; L403-G406 PolarHBondContact O-N 3.06Å; L403-V407 WeakPolarHBondContact O-CG2 3.33Å; L403-V407 PolarHBondContact O-N 2.9Å; L403-F441 HydrophobicContact CD1-CE1 4.36Å; L403-V444 HydrophobicContact CB-CG2 3.89Å; L403-V444 HydrophobicContact CD1-CG1 4.4Å; L403-V444 HydrophobicContact CD1-CG2 4.42Å; L403-F459 HydrophobicContact CD2-CD2 4.07Å; L403-F459 HydrophobicContact CD2-CE2 4.05Å
404	F	94.4	Very high	92.4	Very high	7 Å²	7	18.4 Å²	18.4	3%	0.031	9%	0.087	C	C	.	.	H	α-helix	trans	-72.2	-32	-178	-74.5	-65.5	0	0	0	113.8	I119 I130 R131 A134 I139 L400 R401 G406 V407 V408	I119-F404 HydrophobicContact CD1-CD1 4.16Å; I130-F404 HydrophobicContact CG2-CE1 4.4Å; I130-F404 HydrophobicContact CG2-CZ 4.11Å; R131-F404 HydrophobicContact CB-CD1 3.86Å; R131-F404 HydrophobicContact CB-CE1 3.76Å; R131-F404 HydrophobicContact CB-CZ 4.36Å; R131-F404 HydrophobicContact CG-CD1 4.22Å; R131-F404 HydrophobicContact CG-CG 4.47Å; A134-F404 HydrophobicContact CB-CD2 4.36Å; A134-F404 HydrophobicContact CB-CE2 3.39Å; A134-F404 HydrophobicContact CB-CZ 3.85Å; I139-F404 HydrophobicContact CD1-CD2 4.09Å; L400-F404 HydrophobicContact CD2-CE2 4.45Å; L400-F404 WeakPolarHBondContact O-CD2 3.37Å; L400-F404 PolarHBondContact O-N 3.47Å; R401-F404 PolarHBondContact O-N 3.42Å; F404-G406 VanDerWaalsContact C-N 3.31Å; F404-V407 PolarHBondContact O-N 3.42Å; F404-V408 VanDerWaalsContact O-CG2 3.3Å; F404-V408 WeakPolarHBondContact O-CG2 3.28Å; F404-V408 PolarHBondContact O-N 3.01Å
405	I	94.4	Very high	93	Very high	4 Å²	4	18.1 Å²	18.1	2%	0.021	9%	0.086	C	C	.	.	H	α-helix	trans	-62.8	-43	170.8	-70.8	171.2	0	0	0	109.9	Y102 W254 F255 R401 W402 V407 V408 V409 F436	Y102-I405 HydrophobicContact CE2-CG2 4.37Å; W254-I405 HydrophobicContact CH2-CG2 4.36Å; F255-I405 HydrophobicContact CD1-CD1 4.34Å; F255-I405 HydrophobicContact CE1-CD1 3.97Å; R401-I405 HydrophobicContact CG-CD1 3.79Å; R401-I405 WeakPolarHBondContact O-CB 3.04Å; R401-I405 VanDerWaalsContact O-CG1 3.24Å; R401-I405 WeakPolarHBondContact O-CG1 3.08Å; R401-I405 PolarHBondContact O-N 3.21Å; W402-I405 HydrophobicContact CE3-CD1 4.43Å; W402-I405 HydrophobicContact CZ3-CD1 4.45Å; W402-I405 PolarHBondContact O-N 3.36Å; I405-V407 PolarHBondContact O-N 2.58Å; I405-V408 PolarHBondContact O-N 3.2Å; I405-V409 VanDerWaalsContact O-CG2 3.28Å; I405-V409 WeakPolarHBondContact O-CG2 3.31Å; I405-V409 PolarHBondContact O-N 3.27Å; I405-F436 HydrophobicContact CG2-CE1 3.62Å; I405-F436 HydrophobicContact CG2-CZ 3.93Å
406	G	95.8	Very high	93.5	Very high	0 Å²	0	18.1 Å²	18.1	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-58.8	-44.9	173.7	0	0	0	0	0	112.2	W402 L403 F404 V408 V409 L410	W402-G406 PolarHBondContact O-N 2.68Å; L403-G406 PolarHBondContact O-N 3.06Å; F404-G406 VanDerWaalsContact C-N 3.31Å; G406-V408 PolarHBondContact O-N 2.85Å; G406-V409 PolarHBondContact O-N 3.14Å; G406-L410 VanDerWaalsContact O-CB 3.32Å; G406-L410 WeakPolarHBondContact O-CB 3.36Å; G406-L410 PolarHBondContact O-N 3.38Å
407	V	96.4	Very high	93.8	Very high	22 Å²	22	25.1 Å²	25.1	13%	0.133	11%	0.11	C	C	.	.	H	α-helix	trans	-61.5	-42.3	175	172.8	0	0	0	0	111.7	I119 F123 L403 F404 I405 V409 L410 G411	I119-V407 HydrophobicContact CD1-CG1 4.08Å; I119-V407 HydrophobicContact CG1-CG1 4.3Å; F123-V407 HydrophobicContact CD2-CG1 4.06Å; F123-V407 HydrophobicContact CE2-CG1 3.72Å; F123-V407 WeakPolarHBondContact CE2-O 3.32Å; L403-V407 WeakPolarHBondContact O-CG2 3.33Å; L403-V407 PolarHBondContact O-N 2.9Å; F404-V407 PolarHBondContact O-N 3.42Å; I405-V407 PolarHBondContact O-N 2.58Å; V407-V409 PolarHBondContact O-N 2.81Å; V407-L410 PolarHBondContact O-N 3.35Å; V407-G411 PolarHBondContact O-N 3.24Å
408	V	96.1	Very high	94.1	Very high	1 Å²	1	27.8 Å²	27.8	1%	0.006	13%	0.127	C	C	.	.	H	α-helix	trans	-61.1	-45.1	176.6	169.8	0	0	0	0	111.4	Y102 L105 H115 Y118 I119 F404 I405 G406 G411 L412	Y102-V408 HydrophobicContact CE1-CG1 4.01Å; Y102-V408 HydrophobicContact CE2-CB 4.44Å; Y102-V408 HydrophobicContact CE2-CG1 3.84Å; Y102-V408 VanDerWaalsContact CZ-CG1 3.47Å; Y102-V408 VanDerWaalsContact OH-CB 3.31Å; Y102-V408 WeakPolarHBondContact OH-CB 3.43Å; Y102-V408 VanDerWaalsContact OH-CG1 3.31Å; Y102-V408 WeakPolarHBondContact OH-CG1 3.11Å; L105-V408 HydrophobicContact CD1-CG1 3.41Å; L105-V408 VanDerWaalsContact CD1-CG1 3.41Å; H115-V408 HydrophobicContact CB-CG2 4.06Å; Y118-V408 HydrophobicContact CD2-CG1 3.91Å; Y118-V408 HydrophobicContact CG-CG1 4.44Å; I119-V408 HydrophobicContact CD1-CG2 3.89Å; I119-V408 HydrophobicContact CG1-CG2 3.7Å; F404-V408 VanDerWaalsContact O-CG2 3.3Å; F404-V408 WeakPolarHBondContact O-CG2 3.28Å; F404-V408 PolarHBondContact O-N 3.01Å; I405-V408 PolarHBondContact O-N 3.2Å; G406-V408 PolarHBondContact O-N 2.85Å; V408-G411 CarbonylContact O-C 3.55Å; V408-G411 WeakPolarHBondContact O-CA 2.99Å; V408-G411 PolarHBondContact O-N 2.89Å; V408-G411 VanDerWaalsContact O-N 3.11Å; V408-L412 PolarHBondContact O-N 3.15Å
409	V	96.6	Very high	94.4	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-70.6	-36	-179.3	178.6	0	0	0	0	110.8	C101 Y102 I405 G406 V407 G411 L412 I413 P433 F436 C437	C101-V409 HydrophobicContact CB-CG1 4.48Å; C101-V409 HydrophobicContact CB-CG2 4.37Å; Y102-V409 HydrophobicContact CE2-CG2 4.06Å; I405-V409 VanDerWaalsContact O-CG2 3.28Å; I405-V409 WeakPolarHBondContact O-CG2 3.31Å; I405-V409 PolarHBondContact O-N 3.27Å; G406-V409 PolarHBondContact O-N 3.14Å; V407-V409 PolarHBondContact O-N 2.81Å; V409-G411 VanDerWaalsContact C-N 3.26Å; V409-G411 PolarHBondContact O-N 3.02Å; V409-L412 WeakPolarHBondContact O-CB 3.5Å; V409-L412 PolarHBondContact O-N 3.26Å; V409-L412 VanDerWaalsContact O-N 3.14Å; V409-I413 PolarHBondContact O-N 3.23Å; V409-I413 VanDerWaalsContact O-N 3.11Å; V409-P433 HydrophobicContact CG1-CB 3.74Å; V409-P433 WeakPolarHBondContact CG1-O 3.36Å; V409-F436 HydrophobicContact CB-CD1 4.41Å; V409-F436 HydrophobicContact CG1-CD1 4.24Å; V409-F436 HydrophobicContact CG2-CD1 3.63Å; V409-F436 HydrophobicContact CG2-CE1 3.77Å; V409-C437 HydrophobicContact CG1-CB 4.02Å
410	L	96.9	Very high	94.4	Very high	72 Å²	72	34.6 Å²	34.6	38%	0.377	16%	0.164	S	C	.	.	H	α-helix	trans	-60.9	-39.2	168.9	-175	65.1	0	0	0	110.9	F123 G406 V407 L412 I413 Y414	F123-L410 HydrophobicContact CZ-CG 4.48Å; G406-L410 VanDerWaalsContact O-CB 3.32Å; G406-L410 WeakPolarHBondContact O-CB 3.36Å; G406-L410 PolarHBondContact O-N 3.38Å; V407-L410 PolarHBondContact O-N 3.35Å; L410-L412 VanDerWaalsContact C-N 3.33Å; L410-L412 PolarHBondContact O-N 3Å; L410-I413 PolarHBondContact O-N 3Å; L410-Y414 WeakPolarHBondContact O-CB 3.48Å; L410-Y414 PolarHBondContact O-N 2.83Å
411	G	95.8	Very high	94.3	Very high	2 Å²	2	41.8 Å²	41.8	2%	0.021	20%	0.203	C	C	.	.	H	α-helix	trans	-58.8	-40	171.7	0	0	0	0	0	112.7	V407 V408 V409 Y414 L415	V407-G411 PolarHBondContact O-N 3.24Å; V408-G411 CarbonylContact O-C 3.55Å; V408-G411 WeakPolarHBondContact O-CA 2.99Å; V408-G411 PolarHBondContact O-N 2.89Å; V408-G411 VanDerWaalsContact O-N 3.11Å; V409-G411 VanDerWaalsContact C-N 3.26Å; V409-G411 PolarHBondContact O-N 3.02Å; G411-Y414 PolarHBondContact O-N 3.32Å; G411-L415 WeakPolarHBondContact O-CB 2.83Å; G411-L415 VanDerWaalsContact O-CG 3.22Å; G411-L415 WeakPolarHBondContact O-CG 3.17Å; G411-L415 PolarHBondContact O-N 3.49Å
412	L	95.8	Very high	94.2	Very high	3 Å²	3	42.9 Å²	42.9	2%	0.016	21%	0.21	C	C	.	.	H	α-helix	trans	-60.9	-46.9	172.8	174.5	62.3	0	0	0	111.7	C101 E104 L105 V408 V409 L410 Y414 L415 R416 P433	C101-L412 HydrophobicContact CB-CD2 3.81Å; E104-L412 HydrophobicContact CB-CD1 4.48Å; E104-L412 HydrophobicContact CG-CD1 3.79Å; L105-L412 HydrophobicContact CD1-CB 4.13Å; L105-L412 HydrophobicContact CD2-CB 3.94Å; L105-L412 HydrophobicContact CD2-CD1 3.76Å; L105-L412 HydrophobicContact CD2-CG 4.41Å; L105-L412 HydrophobicContact CG-CB 4.04Å; L105-L412 HydrophobicContact CG-CD1 3.97Å; L105-L412 HydrophobicContact CG-CD2 4.48Å; L105-L412 HydrophobicContact CG-CG 4.38Å; V408-L412 PolarHBondContact O-N 3.15Å; V409-L412 WeakPolarHBondContact O-CB 3.5Å; V409-L412 PolarHBondContact O-N 3.26Å; V409-L412 VanDerWaalsContact O-N 3.14Å; L410-L412 VanDerWaalsContact C-N 3.33Å; L410-L412 PolarHBondContact O-N 3Å; L412-Y414 VanDerWaalsContact C-N 3.34Å; L412-L415 PolarHBondContact O-N 3.27Å; L412-R416 WeakPolarHBondContact O-CG 3.36Å; L412-R416 PolarHBondContact O-N 3.43Å; L412-R416 VanDerWaalsContact O-N 3.14Å; L412-P433 HydrophobicContact CD2-CB 4.23Å
413	I	95.9	Very high	94.1	Very high	23 Å²	23	47.5 Å²	47.5	12%	0.118	24%	0.241	C	C	.	.	H	α-helix	trans	-61.4	-45.9	177.1	-62.1	169.4	0	0	0	109.8	V409 L410 L415 R416 Y417 P433 V434 C437	V409-I413 PolarHBondContact O-N 3.23Å; V409-I413 VanDerWaalsContact O-N 3.11Å; L410-I413 PolarHBondContact O-N 3Å; I413-L415 PolarHBondContact O-N 3.17Å; I413-R416 WeakPolarHBondContact O-CB 3.46Å; I413-R416 PolarHBondContact O-N 3.47Å; I413-Y417 HydrophobicContact CG2-CD2 4.16Å; I413-Y417 HydrophobicContact CG2-CE2 3.71Å; I413-Y417 WeakPolarHBondContact O-CD2 3.48Å; I413-Y417 PolarHBondContact O-N 3.31Å; I413-P433 HydrophobicContact CD1-CB 4.16Å; I413-P433 HydrophobicContact CG1-CB 3.9Å; I413-P433 HydrophobicContact CG1-CG 4.27Å; I413-V434 HydrophobicContact CD1-CG2 4.08Å; I413-C437 HydrophobicContact CD1-CB 4.46Å
414	Y	95.9	Very high	94.1	Very high	110 Å²	110	48.4 Å²	48.4	43%	0.431	24%	0.242	S	C	.	.	H	α-helix	trans	-61	-43.3	178	175.9	-103.8	0	0	0	112.9	A122 F123 L410 G411 L412 R416 Y417 T418	A122-Y414 WeakPolarHBondContact O-CE1 3.28Å; F123-Y414 HydrophobicContact CE1-CD1 4.37Å; F123-Y414 HydrophobicContact CE1-CG 4.41Å; L410-Y414 WeakPolarHBondContact O-CB 3.48Å; L410-Y414 PolarHBondContact O-N 2.83Å; G411-Y414 PolarHBondContact O-N 3.32Å; L412-Y414 VanDerWaalsContact C-N 3.34Å; Y414-R416 PolarHBondContact O-N 2.89Å; Y414-Y417 PolarHBondContact O-N 2.87Å; Y414-Y417 VanDerWaalsContact O-N 3.15Å; Y414-T418 HydrophobicContact CD1-CG2 4.35Å; Y414-T418 HydrophobicContact CD2-CG2 3.94Å; Y414-T418 HydrophobicContact CE1-CG2 3.88Å; Y414-T418 HydrophobicContact CE2-CG2 3.42Å; Y414-T418 VanDerWaalsContact CE2-CG2 3.42Å; Y414-T418 HydrophobicContact CG-CG2 4.39Å; Y414-T418 PolarHBondContact O-N 3.02Å; Y414-T418 PolarHBondContact O-OG1 3.04Å
415	L	94.4	Very high	93.9	Very high	5 Å²	5	51.1 Å²	51.1	3%	0.026	26%	0.26	C	S	.	.	H	α-helix	trans	-64.4	-28.4	176.7	-75.5	171.9	0	0	0	112.4	L105 I109 A122 G411 L412 I413 Y417 K419 R424	L105-L415 HydrophobicContact CD2-CD1 4.23Å; I109-L415 HydrophobicContact CD1-CD1 4.18Å; A122-L415 HydrophobicContact CB-CD1 4.09Å; A122-L415 HydrophobicContact CB-CD2 4.45Å; A122-L415 HydrophobicContact CB-CG 4.06Å; G411-L415 WeakPolarHBondContact O-CB 2.83Å; G411-L415 VanDerWaalsContact O-CG 3.22Å; G411-L415 WeakPolarHBondContact O-CG 3.17Å; G411-L415 PolarHBondContact O-N 3.49Å; L412-L415 PolarHBondContact O-N 3.27Å; I413-L415 PolarHBondContact O-N 3.17Å; L415-Y417 VanDerWaalsContact C-N 3.34Å; L415-K419 HydrophobicContact CD2-CD 3.94Å; L415-K419 CarbonylContact O-C 3.58Å; L415-K419 VanDerWaalsContact O-C 3.31Å; L415-K419 WeakPolarHBondContact O-CA 3Å; L415-K419 PolarHBondContact O-N 2.92Å; L415-K419 VanDerWaalsContact O-O 3.11Å; L415-R424 PolarHBondContact O-NH2 2.86Å
416	R	93.6	Very high	93.9	Very high	31 Å²	31	53.5 Å²	53.5	12%	0.117	27%	0.271	C	S	.	.	H	α-helix	trans	-65.7	-36.6	173.1	-75.1	178.8	168.1	-150.7	-2.9	113	E104 L412 I413 Y414 K427 V428	E104-R416 IonicContact OE1-CZ 3.68Å; E104-R416 VanDerWaalsContact OE1-CZ 3.31Å; E104-R416 IonicContact OE1-NE 2.75Å; E104-R416 PolarHBondContact OE1-NE 2.93Å; E104-R416 IonicContact OE1-NH2 2.64Å; E104-R416 PolarHBondContact OE1-NH2 3.21Å; E104-R416 IonicContact OE2-CZ 2.65Å; E104-R416 IonicContact OE2-NH2 3.31Å; E104-R416 PolarHBondContact OE2-NH2 3.45Å; L412-R416 WeakPolarHBondContact O-CG 3.36Å; L412-R416 PolarHBondContact O-N 3.43Å; L412-R416 VanDerWaalsContact O-N 3.14Å; I413-R416 WeakPolarHBondContact O-CB 3.46Å; I413-R416 PolarHBondContact O-N 3.47Å; Y414-R416 PolarHBondContact O-N 2.89Å; R416-K427 VanDerWaalsContact NH2-CG 3.31Å; R416-V428 VanDerWaalsContact CZ-O 3.28Å; R416-V428 PolarHBondContact NH1-O 2.94Å; R416-V428 PolarHBondContact NH2-O 2.81Å
417	Y	93	Very high	93.8	Very high	165 Å²	165	60 Å²	60	65%	0.647	30%	0.299	S	S	*	.	H	α-helix	trans	-82	-40.1	178.2	-68.9	-70.3	0	0	0	112.7	I413 Y414 L415	I413-Y417 HydrophobicContact CG2-CD2 4.16Å; I413-Y417 HydrophobicContact CG2-CE2 3.71Å; I413-Y417 WeakPolarHBondContact O-CD2 3.48Å; I413-Y417 PolarHBondContact O-N 3.31Å; Y414-Y417 PolarHBondContact O-N 2.87Å; Y414-Y417 VanDerWaalsContact O-N 3.15Å; L415-Y417 VanDerWaalsContact C-N 3.34Å
418	T	94.1	Very high	93.7	Very high	64 Å²	64	59.3 Å²	59.3	39%	0.393	30%	0.295	S	S	.	.	H	α-helix	trans	-87.8	-32.5	-173.3	52.8	0	0	0	0	114.6	Y414 P420	Y414-T418 HydrophobicContact CD1-CG2 4.35Å; Y414-T418 HydrophobicContact CD2-CG2 3.94Å; Y414-T418 HydrophobicContact CE1-CG2 3.88Å; Y414-T418 HydrophobicContact CE2-CG2 3.42Å; Y414-T418 VanDerWaalsContact CE2-CG2 3.42Å; Y414-T418 HydrophobicContact CG-CG2 4.39Å; Y414-T418 PolarHBondContact O-N 3.02Å; Y414-T418 PolarHBondContact O-OG1 3.04Å; T418-P420 VanDerWaalsContact C-CD 3.49Å
419	K	92.4	Very high	93.7	Very high	81 Å²	81	62.6 Å²	62.6	35%	0.352	32%	0.316	S	S	.	.			trans	-126.7	69.5	178.6	-65.2	178.8	-178.8	163.2	0	109.4	E121 L415 D421 L422 R424	E121-K419 PolarHBondContact O-NZ 3.26Å; E121-K419 IonicContact OE1-NZ 3Å; E121-K419 PolarHBondContact OE1-NZ 2.87Å; L415-K419 HydrophobicContact CD2-CD 3.94Å; L415-K419 CarbonylContact O-C 3.58Å; L415-K419 VanDerWaalsContact O-C 3.31Å; L415-K419 WeakPolarHBondContact O-CA 3Å; L415-K419 PolarHBondContact O-N 2.92Å; L415-K419 VanDerWaalsContact O-O 3.11Å; K419-D421 VanDerWaalsContact C-N 3.3Å; K419-D421 PolarHBondContact O-N 3.04Å; K419-L422 HydrophobicContact CB-CB 4.43Å; K419-L422 PolarHBondContact O-N 3.38Å; K419-R424 PolarHBondContact O-NH2 2.9Å
420	P	90.4	Very high	93.6	Very high	74 Å²	74	65.8 Å²	65.8	48%	0.481	33%	0.333	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.3	-34.4	-177.1	26.2	-33.7	0	0	0	112.5	T418 L422 R424	T418-P420 VanDerWaalsContact C-CD 3.49Å; P420-L422 VanDerWaalsContact C-N 3.28Å; P420-L422 PolarHBondContact O-N 3.39Å; P420-R424 PolarHBondContact O-NH1 3.4Å
421	D	90.9	Very high	93.5	Very high	152 Å²	152	67.9 Å²	67.9	81%	0.813	34%	0.339	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.4	-0.3	-174.8	-53.5	-44.1	0	0	0	114.3	K419	K419-D421 VanDerWaalsContact C-N 3.3Å; K419-D421 PolarHBondContact O-N 3.04Å
422	L	89.6	Confident	93.6	Very high	54 Å²	54	68.4 Å²	68.4	28%	0.283	34%	0.341	S	S	.	.	S	Bend	trans	-61.3	128.7	175.7	-167.7	77.5	0	0	0	109	C108 K419 P420 R424	C108-L422 HydrophobicContact CB-CD2 4.01Å; K419-L422 HydrophobicContact CB-CB 4.43Å; K419-L422 PolarHBondContact O-N 3.38Å; P420-L422 VanDerWaalsContact C-N 3.28Å; P420-L422 PolarHBondContact O-N 3.39Å; L422-R424 VanDerWaalsContact O-CG 3.28Å; L422-R424 WeakPolarHBondContact O-CG 3.45Å; L422-R424 PolarHBondContact O-N 3.2Å; L422-R424 VanDerWaalsContact O-N 3.15Å
423	P	90.3	Very high	93.6	Very high	100 Å²	100	68.2 Å²	68.2	65%	0.649	34%	0.341	S	S	*	.			trans	-63	120.9	179.4	25.2	-33.3	0	0	0	109.7	P425	P423-P425 WeakPolarHBondContact O-CD 3.43Å
424	R	92.2	Very high	93.6	Very high	47 Å²	47	69.9 Å²	69.9	18%	0.177	35%	0.352	C	S	.	.			trans	-116.1	90.2	178.7	-52.3	-160.6	172.3	92.1	7	110.2	E104 C108 L415 K419 P420 L422 F426	E104-R424 WeakPolarHBondContact OE1-CD 3.29Å; E104-R424 IonicContact OE1-NE 3.76Å; C108-R424 VanDerWaalsContact SG-CG 3.54Å; L415-R424 PolarHBondContact O-NH2 2.86Å; K419-R424 PolarHBondContact O-NH2 2.9Å; P420-R424 PolarHBondContact O-NH1 3.4Å; L422-R424 VanDerWaalsContact O-CG 3.28Å; L422-R424 WeakPolarHBondContact O-CG 3.45Å; L422-R424 PolarHBondContact O-N 3.2Å; L422-R424 VanDerWaalsContact O-N 3.15Å; R424-F426 PolarHBondContact O-N 3.16Å
425	P	91.6	Very high	93.7	Very high	63 Å²	63	67.2 Å²	67.2	41%	0.409	35%	0.347	S	S	.	.	S	Bend	trans	-61.1	-33.1	179.6	-24.2	35	0	0	0	112.9	E268 P423	E268-P425 HydrophobicContact CB-CB 3.95Å; E268-P425 HydrophobicContact CB-CG 4.49Å; E268-P425 HydrophobicContact CG-CB 3.81Å; E268-P425 HydrophobicContact CG-CG 3.79Å; P423-P425 WeakPolarHBondContact O-CD 3.43Å
426	F	93.1	Very high	93.7	Very high	54 Å²	54	67 Å²	67	24%	0.237	35%	0.345	C	S	.	.	S	Bend	trans	-123.2	128.1	173.5	-179.5	-99.4	0	0	0	109.1	L100 A103 E104 T107 P272 R424 V428	L100-F426 HydrophobicContact CD2-CE1 4.41Å; L100-F426 HydrophobicContact CD2-CZ 3.98Å; A103-F426 HydrophobicContact CB-CD1 3.97Å; A103-F426 HydrophobicContact CB-CE1 3.82Å; E104-F426 HydrophobicContact CB-CD1 4.2Å; E104-F426 WeakPolarHBondContact CG-O 3.49Å; T107-F426 HydrophobicContact CG2-CB 4.12Å; P272-F426 HydrophobicContact CB-CD1 4.29Å; P272-F426 HydrophobicContact CB-CD2 3.74Å; P272-F426 HydrophobicContact CB-CE1 4.34Å; P272-F426 HydrophobicContact CB-CE2 3.8Å; P272-F426 HydrophobicContact CB-CG 3.99Å; P272-F426 HydrophobicContact CB-CZ 4.11Å; P272-F426 HydrophobicContact CG-CB 3.89Å; P272-F426 HydrophobicContact CG-CD1 4.09Å; P272-F426 HydrophobicContact CG-CD2 3.79Å; P272-F426 HydrophobicContact CG-CE2 4.35Å; P272-F426 HydrophobicContact CG-CG 3.64Å; R424-F426 PolarHBondContact O-N 3.16Å; F426-V428 HydrophobicContact CE1-CG1 3.61Å; F426-V428 HydrophobicContact CZ-CG1 4.02Å
427	K	94	Very high	93.8	Very high	138 Å²	138	66 Å²	66	60%	0.6	34%	0.343	S	S	*	.			trans	-136.5	121.6	-174.5	-173.4	-177.4	179.6	-179.2	0	110.4	R416	R416-K427 VanDerWaalsContact NH2-CG 3.31Å
428	V	95	Very high	93.9	Very high	7 Å²	7	63.6 Å²	63.6	4%	0.042	34%	0.341	C	S	.	.			trans	-87.1	151.9	176.1	-64.4	0	0	0	0	112.2	L100 E104 R416 F426 I432 P433	L100-V428 HydrophobicContact CB-CG1 3.76Å; E104-V428 WeakPolarHBondContact OE2-CG2 3.47Å; E104-V428 PolarHBondContact OE2-N 2.93Å; R416-V428 VanDerWaalsContact CZ-O 3.28Å; R416-V428 PolarHBondContact NH1-O 2.94Å; R416-V428 PolarHBondContact NH2-O 2.81Å; F426-V428 HydrophobicContact CE1-CG1 3.61Å; F426-V428 HydrophobicContact CZ-CG1 4.02Å; V428-I432 HydrophobicContact CB-CB 4.48Å; V428-I432 HydrophobicContact CB-CD1 4.3Å; V428-I432 HydrophobicContact CG2-CB 4.47Å; V428-P433 HydrophobicContact CG2-CG 4.44Å
429	P	96	Very high	93.9	Very high	70 Å²	70	61.6 Å²	61.6	46%	0.455	33%	0.328	S	S	.	.			trans	-61.2	144.4	169.5	26.4	-35.1	0	0	0	110.8	F431 I432 P433	P429-F431 HydrophobicContact CB-CD1 3.66Å; P429-F431 HydrophobicContact CB-CE1 3.62Å; P429-F431 HydrophobicContact CG-CD1 3.81Å; P429-F431 HydrophobicContact CG-CE1 3.28Å; P429-F431 HydrophobicContact CG-CZ 4.03Å; P429-F431 PolarHBondContact O-N 3.41Å; P429-F431 VanDerWaalsContact O-N 3.13Å; P429-I432 HydrophobicContact CG-CD1 3.73Å; P429-I432 HydrophobicContact CG-CG1 3.99Å; P429-I432 PolarHBondContact O-N 3.13Å; P429-I432 VanDerWaalsContact O-N 3.12Å; P429-P433 VanDerWaalsContact O-CD 3.22Å; P429-P433 WeakPolarHBondContact O-CD 3.32Å
430	L	94.3	Very high	93.9	Very high	66 Å²	66	57.7 Å²	57.7	35%	0.346	31%	0.312	S	S	.	.	T	Hydrogen-bonded Turn	trans	-61.8	-24.6	-170.8	-163.2	80.8	0	0	0	113.5	I432 P433 V434	L430-I432 PolarHBondContact O-N 2.52Å; L430-P433 WeakPolarHBondContact O-CD 3.23Å; L430-P433 VanDerWaalsContact O-CG 3.26Å; L430-P433 WeakPolarHBondContact O-CG 3.14Å; L430-V434 HydrophobicContact CG-CG2 4.33Å; L430-V434 WeakPolarHBondContact O-CG2 3.27Å; L430-V434 PolarHBondContact O-N 3.31Å
431	F	96	Very high	94	Very high	116 Å²	116	58.1 Å²	58.1	51%	0.509	31%	0.306	S	S	.	.	H	α-helix	trans	-63.6	-31.5	178	80.8	-96.3	0	0	0	112.3	F97 P429 V434 V435	F97-F431 HydrophobicContact CZ-CE2 4.2Å; P429-F431 HydrophobicContact CB-CD1 3.66Å; P429-F431 HydrophobicContact CB-CE1 3.62Å; P429-F431 HydrophobicContact CG-CD1 3.81Å; P429-F431 HydrophobicContact CG-CE1 3.28Å; P429-F431 HydrophobicContact CG-CZ 4.03Å; P429-F431 PolarHBondContact O-N 3.41Å; P429-F431 VanDerWaalsContact O-N 3.13Å; F431-V434 PolarHBondContact O-N 3.48Å; F431-V435 WeakPolarHBondContact O-CB 3.07Å; F431-V435 VanDerWaalsContact O-CG2 3.24Å; F431-V435 WeakPolarHBondContact O-CG2 2.97Å; F431-V435 PolarHBondContact O-N 3.32Å
432	I	96.3	Very high	94.1	Very high	13 Å²	13	55.3 Å²	55.3	7%	0.067	29%	0.287	C	S	.	.	H	α-helix	trans	-61.3	-56.6	-179.7	-67.9	-177.1	0	0	0	111.4	F97 L100 V428 P429 L430 V434 F436	F97-I432 HydrophobicContact CB-CG2 3.68Å; F97-I432 HydrophobicContact CD1-CD1 4.44Å; F97-I432 HydrophobicContact CD1-CG1 4.29Å; F97-I432 HydrophobicContact CD1-CG2 4.08Å; F97-I432 HydrophobicContact CE1-CG1 4.4Å; F97-I432 HydrophobicContact CG-CG2 3.91Å; F97-I432 WeakPolarHBondContact O-CG2 2.99Å; L100-I432 HydrophobicContact CD1-CD1 4.21Å; V428-I432 HydrophobicContact CB-CB 4.48Å; V428-I432 HydrophobicContact CB-CD1 4.3Å; V428-I432 HydrophobicContact CG2-CB 4.47Å; P429-I432 HydrophobicContact CG-CD1 3.73Å; P429-I432 HydrophobicContact CG-CG1 3.99Å; P429-I432 PolarHBondContact O-N 3.13Å; P429-I432 VanDerWaalsContact O-N 3.12Å; L430-I432 PolarHBondContact O-N 2.52Å; I432-V434 VanDerWaalsContact C-N 3.3Å; I432-V434 PolarHBondContact O-N 3.14Å; I432-F436 WeakPolarHBondContact O-CB 3.48Å; I432-F436 PolarHBondContact O-N 3.34Å
433	P	96.5	Very high	94.1	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-64.6	-33.7	177.2	22.7	-31.6	0	0	0	112.5	C101 V409 L412 I413 V428 P429 L430 C437	C101-P433 WeakPolarHBondContact SG-CA 3.3Å; C101-P433 VanDerWaalsContact SG-CB 3.59Å; V409-P433 HydrophobicContact CG1-CB 3.74Å; V409-P433 WeakPolarHBondContact CG1-O 3.36Å; L412-P433 HydrophobicContact CD2-CB 4.23Å; I413-P433 HydrophobicContact CD1-CB 4.16Å; I413-P433 HydrophobicContact CG1-CB 3.9Å; I413-P433 HydrophobicContact CG1-CG 4.27Å; V428-P433 HydrophobicContact CG2-CG 4.44Å; P429-P433 VanDerWaalsContact O-CD 3.22Å; P429-P433 WeakPolarHBondContact O-CD 3.32Å; L430-P433 WeakPolarHBondContact O-CD 3.23Å; L430-P433 VanDerWaalsContact O-CG 3.26Å; L430-P433 WeakPolarHBondContact O-CG 3.14Å; P433-C437 WeakPolarHBondContact O-CB 3.21Å; P433-C437 PolarHBondContact O-N 3.18Å
434	V	96.6	Very high	94.1	Very high	58 Å²	58	49 Å²	49	35%	0.352	25%	0.248	S	C	.	.	H	α-helix	trans	-64.4	-52.6	177.8	172.5	0	0	0	0	111	I413 L430 F431 I432 F436 C437 L438	I413-V434 HydrophobicContact CD1-CG2 4.08Å; L430-V434 HydrophobicContact CG-CG2 4.33Å; L430-V434 WeakPolarHBondContact O-CG2 3.27Å; L430-V434 PolarHBondContact O-N 3.31Å; F431-V434 PolarHBondContact O-N 3.48Å; I432-V434 VanDerWaalsContact C-N 3.3Å; I432-V434 PolarHBondContact O-N 3.14Å; V434-F436 VanDerWaalsContact C-N 3.34Å; V434-F436 PolarHBondContact O-N 3.25Å; V434-C437 PolarHBondContact O-N 3.42Å; V434-L438 HydrophobicContact CG1-CD1 4.27Å; V434-L438 WeakPolarHBondContact O-CG 3.32Å; V434-L438 PolarHBondContact O-N 3.48Å
435	V	96.5	Very high	94	Very high	54 Å²	54	52.7 Å²	52.7	33%	0.327	27%	0.266	S	S	.	.	H	α-helix	trans	-60.3	-46.1	178.9	170.5	0	0	0	0	110.4	L94 F97 F431 C437 L438 T439	L94-V435 HydrophobicContact CD2-CG1 4.41Å; F97-V435 HydrophobicContact CD2-CB 4.46Å; F97-V435 HydrophobicContact CD2-CG1 4.09Å; F97-V435 HydrophobicContact CE2-CG1 4.14Å; F431-V435 WeakPolarHBondContact O-CB 3.07Å; F431-V435 VanDerWaalsContact O-CG2 3.24Å; F431-V435 WeakPolarHBondContact O-CG2 2.97Å; F431-V435 PolarHBondContact O-N 3.32Å; V435-C437 PolarHBondContact O-N 2.96Å; V435-L438 PolarHBondContact O-N 3.02Å; V435-T439 PolarHBondContact O-N 3.45Å; V435-T439 PolarHBondContact O-OG1 3.3Å; V435-T439 VanDerWaalsContact O-OG1 3.06Å
436	F	95.7	Very high	93.7	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-66.7	-38.6	-179.8	-174.9	-107.2	0	0	0	112.7	L94 F97 G98 M248 W254 W402 I405 V409 I432 V434 T439 C440	L94-F436 WeakPolarHBondContact O-CD2 3.32Å; L94-F436 WeakPolarHBondContact O-CE2 3.2Å; F97-F436 HydrophobicContact CB-CB 4.07Å; F97-F436 HydrophobicContact CB-CD2 4.38Å; F97-F436 HydrophobicContact CB-CG 4.49Å; G98-F436 VanDerWaalsContact CA-CD1 3.4Å; G98-F436 VanDerWaalsContact CA-CZ 3.44Å; M248-F436 HydrophobicContact CE-CE2 4.19Å; W254-F436 HydrophobicContact CH2-CE1 4.3Å; W254-F436 HydrophobicContact CH2-CZ 4.2Å; W254-F436 HydrophobicContact CZ2-CE1 4.31Å; W254-F436 AromaticContact CZ2-CZ 3.75Å; W254-F436 HydrophobicContact CZ2-CZ 3.75Å; W402-F436 HydrophobicContact CZ3-CE2 4.45Å; W402-F436 HydrophobicContact CZ3-CZ 4.1Å; I405-F436 HydrophobicContact CG2-CE1 3.62Å; I405-F436 HydrophobicContact CG2-CZ 3.93Å; V409-F436 HydrophobicContact CB-CD1 4.41Å; V409-F436 HydrophobicContact CG1-CD1 4.24Å; V409-F436 HydrophobicContact CG2-CD1 3.63Å; V409-F436 HydrophobicContact CG2-CE1 3.77Å; I432-F436 WeakPolarHBondContact O-CB 3.48Å; I432-F436 PolarHBondContact O-N 3.34Å; V434-F436 VanDerWaalsContact C-N 3.34Å; V434-F436 PolarHBondContact O-N 3.25Å; F436-T439 WeakPolarHBondContact O-CB 3.31Å; F436-T439 PolarHBondContact O-N 3.03Å; F436-C440 WeakPolarHBondContact CE1-SG 3.12Å; F436-C440 PolarHBondContact O-N 3.4Å; F436-C440 PolarHBondContact O-SG 2.99Å
437	C	95.8	Very high	93.4	Very high	9 Å²	9	47.7 Å²	47.7	6%	0.061	24%	0.238	C	C	.	.	H	α-helix	trans	-62.1	-43.3	175.3	-170.2	0	0	0	0	111.4	V409 I413 P433 V434 V435 T439 C440 F441	V409-C437 HydrophobicContact CG1-CB 4.02Å; I413-C437 HydrophobicContact CD1-CB 4.46Å; P433-C437 WeakPolarHBondContact O-CB 3.21Å; P433-C437 PolarHBondContact O-N 3.18Å; V434-C437 PolarHBondContact O-N 3.42Å; V435-C437 PolarHBondContact O-N 2.96Å; C437-T439 VanDerWaalsContact C-N 3.35Å; C437-T439 PolarHBondContact O-N 3.21Å; C437-C440 PolarHBondContact O-N 3.43Å; C437-F441 VanDerWaalsContact O-CD2 3.24Å; C437-F441 WeakPolarHBondContact O-CD2 3.39Å; C437-F441 PolarHBondContact O-N 3.25Å; C437-F441 WeakPolarHBondContact SG-CE2 3.45Å
438	L	95.3	Very high	93.1	Very high	116 Å²	116	45 Å²	45	61%	0.607	23%	0.23	S	C	*	.	H	α-helix	trans	-59.8	-44.2	172.5	-69.7	172.5	0	0	0	111.5	V434 V435 C440 F441 F442	V434-L438 HydrophobicContact CG1-CD1 4.27Å; V434-L438 WeakPolarHBondContact O-CG 3.32Å; V434-L438 PolarHBondContact O-N 3.48Å; V435-L438 PolarHBondContact O-N 3.02Å; L438-C440 VanDerWaalsContact C-N 3.34Å; L438-C440 PolarHBondContact O-N 3.4Å; L438-F441 PolarHBondContact O-N 3.41Å; L438-F442 VanDerWaalsContact O-CB 3.27Å; L438-F442 WeakPolarHBondContact O-CB 2.94Å; L438-F442 PolarHBondContact O-N 3.3Å
439	T	92.9	Very high	92.7	Very high	21 Å²	21	53.4 Å²	53.4	13%	0.129	26%	0.262	C	S	.	.	H	α-helix	trans	-60.1	-42.3	174.9	-58.6	0	0	0	0	111.9	L94 V435 F436 C437 F442 M443	L94-T439 HydrophobicContact CD1-CG2 4.04Å; L94-T439 HydrophobicContact CD2-CG2 4.42Å; V435-T439 PolarHBondContact O-N 3.45Å; V435-T439 PolarHBondContact O-OG1 3.3Å; V435-T439 VanDerWaalsContact O-OG1 3.06Å; F436-T439 WeakPolarHBondContact O-CB 3.31Å; F436-T439 PolarHBondContact O-N 3.03Å; C437-T439 VanDerWaalsContact C-N 3.35Å; C437-T439 PolarHBondContact O-N 3.21Å; T439-F442 PolarHBondContact O-N 2.93Å; T439-M443 VanDerWaalsContact O-CG 3.29Å; T439-M443 WeakPolarHBondContact O-CG 3.26Å; T439-M443 PolarHBondContact O-N 3.14Å
440	C	93.5	Very high	91.9	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-61.4	-48.5	176.6	-68.4	0	0	0	0	111.8	F436 C437 L438 F442 M443 V444	F436-C440 WeakPolarHBondContact CE1-SG 3.12Å; F436-C440 PolarHBondContact O-N 3.4Å; F436-C440 PolarHBondContact O-SG 2.99Å; C437-C440 PolarHBondContact O-N 3.43Å; L438-C440 VanDerWaalsContact C-N 3.34Å; L438-C440 PolarHBondContact O-N 3.4Å; C440-F442 VanDerWaalsContact C-N 3.32Å; C440-F442 PolarHBondContact O-N 3.47Å; C440-M443 WeakPolarHBondContact O-CB 3.45Å; C440-M443 PolarHBondContact O-N 2.97Å; C440-V444 WeakPolarHBondContact O-CG2 3.43Å; C440-V444 PolarHBondContact O-N 3.44Å
441	F	92.9	Very high	91.4	Very high	83 Å²	83	50.6 Å²	50.6	36%	0.364	25%	0.248	S	C	.	.	H	α-helix	trans	-68.3	-33	179	-72.6	-59	0	0	0	112.8	L403 C437 L438 V444 F445	L403-F441 HydrophobicContact CD1-CE1 4.36Å; C437-F441 VanDerWaalsContact O-CD2 3.24Å; C437-F441 WeakPolarHBondContact O-CD2 3.39Å; C437-F441 PolarHBondContact O-N 3.25Å; C437-F441 WeakPolarHBondContact SG-CE2 3.45Å; L438-F441 PolarHBondContact O-N 3.41Å; F441-V444 WeakPolarHBondContact O-CB 2.92Å; F441-V444 PolarHBondContact O-N 2.83Å; F441-F445 PolarHBondContact O-N 3.31Å
442	F	91.4	Very high	91.1	Very high	93 Å²	93	49 Å²	49	41%	0.408	25%	0.249	S	C	.	.	H	α-helix	trans	-60.9	-45.2	169.7	-179.3	-115	0	0	0	111.3	P241 L438 T439 C440 V444 F445 L446	P241-F442 HydrophobicContact CB-CE1 4.18Å; P241-F442 HydrophobicContact CB-CZ 3.86Å; P241-F442 HydrophobicContact CG-CZ 4.06Å; L438-F442 VanDerWaalsContact O-CB 3.27Å; L438-F442 WeakPolarHBondContact O-CB 2.94Å; L438-F442 PolarHBondContact O-N 3.3Å; T439-F442 PolarHBondContact O-N 2.93Å; C440-F442 VanDerWaalsContact C-N 3.32Å; C440-F442 PolarHBondContact O-N 3.47Å; F442-V444 VanDerWaalsContact C-N 3.33Å; F442-V444 PolarHBondContact O-N 3.43Å; F442-F445 WeakPolarHBondContact O-CB 3.3Å; F442-F445 PolarHBondContact O-N 2.87Å; F442-L446 HydrophobicContact CD1-CD1 3.91Å; F442-L446 HydrophobicContact CD1-CG 4.47Å; F442-L446 HydrophobicContact CE1-CD1 3.55Å; F442-L446 HydrophobicContact CE1-CG 4.22Å; F442-L446 HydrophobicContact CE2-CD1 4.49Å; F442-L446 HydrophobicContact CE2-CD2 4.24Å; F442-L446 HydrophobicContact CE2-CG 4.3Å; F442-L446 HydrophobicContact CZ-CD1 3.87Å; F442-L446 HydrophobicContact CZ-CD2 4.09Å; F442-L446 HydrophobicContact CZ-CG 4.12Å; F442-L446 WeakPolarHBondContact O-CG 3.27Å; F442-L446 PolarHBondContact O-N 3.4Å
443	M	89.6	Confident	90.8	Very high	2 Å²	2	55.6 Å²	55.6	1%	0.01	28%	0.277	C	S	.	.	H	α-helix	trans	-60.8	-41.1	174.8	-71	-63.3	164.6	0	0	112.7	F244 Y245 M248 W402 T439 C440 F445 L446 S447	F244-M443 HydrophobicContact CB-CE 3.53Å; Y245-M443 HydrophobicContact CD2-SD 4.08Å; M248-M443 HydrophobicContact CB-CE 4.45Å; M248-M443 HydrophobicContact CG-CE 3.82Å; W402-M443 HydrophobicContact CB-CB 4.15Å; W402-M443 HydrophobicContact CD2-CB 4.18Å; W402-M443 HydrophobicContact CD2-CG 4.39Å; W402-M443 HydrophobicContact CG-CB 3.8Å; W402-M443 HydrophobicContact CG-CG 4.49Å; T439-M443 VanDerWaalsContact O-CG 3.29Å; T439-M443 WeakPolarHBondContact O-CG 3.26Å; T439-M443 PolarHBondContact O-N 3.14Å; C440-M443 WeakPolarHBondContact O-CB 3.45Å; C440-M443 PolarHBondContact O-N 2.97Å; M443-F445 VanDerWaalsContact C-N 3.34Å; M443-F445 PolarHBondContact O-N 3.41Å; M443-L446 PolarHBondContact O-N 3.1Å; M443-L446 HydrophobicContact SD-CD1 4.16Å; M443-S447 PolarHBondContact O-N 3.33Å; M443-S447 PolarHBondContact O-OG 3.01Å; M443-S447 VanDerWaalsContact O-OG 3.06Å
444	V	91.7	Very high	90.3	Very high	18 Å²	18	57.6 Å²	57.6	11%	0.109	29%	0.288	C	S	.	.	H	α-helix	trans	-58.7	-47.1	174.7	170.6	0	0	0	0	110.8	F399 W402 L403 C440 F441 F442 L446 S447 L448	F399-V444 HydrophobicContact CD2-CG1 3.9Å; F399-V444 HydrophobicContact CE2-CG1 3.46Å; F399-V444 VanDerWaalsContact CE2-CG1 3.46Å; F399-V444 HydrophobicContact CZ-CG1 4.23Å; W402-V444 HydrophobicContact CB-CG2 3.93Å; L403-V444 HydrophobicContact CB-CG2 3.89Å; L403-V444 HydrophobicContact CD1-CG1 4.4Å; L403-V444 HydrophobicContact CD1-CG2 4.42Å; C440-V444 WeakPolarHBondContact O-CG2 3.43Å; C440-V444 PolarHBondContact O-N 3.44Å; F441-V444 WeakPolarHBondContact O-CB 2.92Å; F441-V444 PolarHBondContact O-N 2.83Å; F442-V444 VanDerWaalsContact C-N 3.33Å; F442-V444 PolarHBondContact O-N 3.43Å; V444-L446 PolarHBondContact O-N 2.98Å; V444-S447 PolarHBondContact O-N 2.94Å; V444-L448 PolarHBondContact O-N 3.11Å
445	F	89.6	Confident	89.9	Confident	125 Å²	125	54.9 Å²	54.9	55%	0.548	27%	0.271	S	S	.	.	H	α-helix	trans	-60.9	-43.8	176.9	175.2	-97.9	0	0	0	112	F441 F442 M443 S447 L448 Y449	F441-F445 PolarHBondContact O-N 3.31Å; F442-F445 WeakPolarHBondContact O-CB 3.3Å; F442-F445 PolarHBondContact O-N 2.87Å; M443-F445 VanDerWaalsContact C-N 3.34Å; M443-F445 PolarHBondContact O-N 3.41Å; F445-S447 PolarHBondContact O-N 3.2Å; F445-L448 WeakPolarHBondContact O-CB 3.01Å; F445-L448 PolarHBondContact O-N 2.96Å; F445-Y449 WeakPolarHBondContact O-CB 3.42Å; F445-Y449 PolarHBondContact O-N 3.17Å
446	L	85.8	Confident	89.6	Confident	12 Å²	12	53.8 Å²	53.8	6%	0.063	27%	0.272	C	S	.	.	H	α-helix	trans	-64	-41.4	177.6	-68	175.2	0	0	0	112.8	P241 F442 M443 V444 L448 Y449 S450	P241-L446 HydrophobicContact CB-CD1 3.38Å; P241-L446 HydrophobicContact CB-CD2 3.33Å; P241-L446 HydrophobicContact CB-CG 3.94Å; P241-L446 HydrophobicContact CG-CD2 4.24Å; P241-L446 WeakPolarHBondContact O-CD1 3.37Å; F442-L446 HydrophobicContact CD1-CD1 3.91Å; F442-L446 HydrophobicContact CD1-CG 4.47Å; F442-L446 HydrophobicContact CE1-CD1 3.55Å; F442-L446 HydrophobicContact CE1-CG 4.22Å; F442-L446 HydrophobicContact CE2-CD1 4.49Å; F442-L446 HydrophobicContact CE2-CD2 4.24Å; F442-L446 HydrophobicContact CE2-CG 4.3Å; F442-L446 HydrophobicContact CZ-CD1 3.87Å; F442-L446 HydrophobicContact CZ-CD2 4.09Å; F442-L446 HydrophobicContact CZ-CG 4.12Å; F442-L446 WeakPolarHBondContact O-CG 3.27Å; F442-L446 PolarHBondContact O-N 3.4Å; M443-L446 PolarHBondContact O-N 3.1Å; M443-L446 HydrophobicContact SD-CD1 4.16Å; V444-L446 PolarHBondContact O-N 2.98Å; L446-L448 VanDerWaalsContact C-N 3.29Å; L446-L448 PolarHBondContact O-N 3.4Å; L446-Y449 PolarHBondContact O-N 3.45Å; L446-S450 VanDerWaalsContact O-CB 3.3Å; L446-S450 WeakPolarHBondContact O-CB 3.29Å; L446-S450 PolarHBondContact O-N 3.01Å; L446-S450 PolarHBondContact O-OG 2.87Å
447	S	85.8	Confident	89.4	Confident	1 Å²	1	56.7 Å²	56.7	1%	0.007	29%	0.289	C	S	.	.	H	α-helix	trans	-61.5	-41.7	175.5	-58.3	0	0	0	0	110.9	Y245 M443 V444 F445 S450 D451 T455	Y245-S447 VanDerWaalsContact CE2-OG 3.25Å; Y245-S447 WeakPolarHBondContact CE2-OG 3.38Å; M443-S447 PolarHBondContact O-N 3.33Å; M443-S447 PolarHBondContact O-OG 3.01Å; M443-S447 VanDerWaalsContact O-OG 3.06Å; V444-S447 PolarHBondContact O-N 2.94Å; F445-S447 PolarHBondContact O-N 3.2Å; S447-S450 PolarHBondContact O-N 3.36Å; S447-D451 PolarHBondContact O-N 3.37Å; S447-T455 WeakPolarHBondContact O-CG2 3.48Å
448	L	87.8	Confident	89	Confident	80 Å²	80	56.2 Å²	56.2	42%	0.419	29%	0.286	S	S	.	.	H	α-helix	trans	-64.4	-41.8	176.6	-174.1	69.7	0	0	0	112.3	V444 F445 L446 P452	V444-L448 PolarHBondContact O-N 3.11Å; F445-L448 WeakPolarHBondContact O-CB 3.01Å; F445-L448 PolarHBondContact O-N 2.96Å; L446-L448 VanDerWaalsContact C-N 3.29Å; L446-L448 PolarHBondContact O-N 3.4Å; L448-P452 WeakPolarHBondContact O-CA 3.48Å; L448-P452 WeakPolarHBondContact O-CB 3.29Å; L448-P452 WeakPolarHBondContact O-CD 3.42Å
449	Y	85.9	Confident	88.8	Confident	184 Å²	184	55 Å²	55	72%	0.722	28%	0.276	S	S	*	.	H	α-helix	trans	-66.5	-40.6	177.1	176.4	-100.7	0	0	0	112.3	F445 L446	F445-Y449 WeakPolarHBondContact O-CB 3.42Å; F445-Y449 PolarHBondContact O-N 3.17Å; L446-Y449 PolarHBondContact O-N 3.45Å
450	S	81.2	Confident	88.8	Confident	53 Å²	53	56.5 Å²	56.5	37%	0.371	29%	0.291	S	S	.	.	H	α-helix	trans	-75.1	-37.8	-174.5	-53.2	0	0	0	0	112.6	L242 L446 S447	L242-S450 VanDerWaalsContact CD2-OG 3.31Å; L242-S450 WeakPolarHBondContact CD2-OG 3.34Å; L446-S450 VanDerWaalsContact O-CB 3.3Å; L446-S450 WeakPolarHBondContact O-CB 3.29Å; L446-S450 PolarHBondContact O-N 3.01Å; L446-S450 PolarHBondContact O-OG 2.87Å; S447-S450 PolarHBondContact O-N 3.36Å
451	D	82.9	Confident	88.7	Confident	25 Å²	25	59.1 Å²	59.1	13%	0.134	30%	0.303	C	S	.	.			trans	-147.6	74	-175.8	-171	-7.8	0	0	0	110.7	N395 S447 F453 N454 T455	N395-D451 HydrophobicContact CB-CB 4.31Å; S447-D451 PolarHBondContact O-N 3.37Å; D451-F453 PolarHBondContact O-N 2.92Å; D451-N454 VanDerWaalsContact CG-ND2 3.32Å; D451-N454 PolarHBondContact OD1-N 2.96Å; D451-N454 PolarHBondContact OD1-ND2 3.12Å; D451-N454 WeakPolarHBondContact OD2-CB 3.45Å; D451-N454 PolarHBondContact OD2-ND2 3.4Å; D451-T455 WeakPolarHBondContact O-CB 3.49Å; D451-T455 VanDerWaalsContact O-CG2 3.31Å; D451-T455 WeakPolarHBondContact O-CG2 3.27Å; D451-T455 PolarHBondContact O-N 3.44Å; D451-T455 VanDerWaalsContact O-N 3.15Å; D451-T455 PolarHBondContact O-OG1 3.07Å
452	P	89.4	Confident	88.7	Confident	81 Å²	81	55.3 Å²	55.3	53%	0.526	29%	0.287	S	S	.	.	H	α-helix	trans	-64.8	-28.8	-173.3	23.6	-33.4	0	0	0	112.8	L448 T455 G456	L448-P452 WeakPolarHBondContact O-CA 3.48Å; L448-P452 WeakPolarHBondContact O-CB 3.29Å; L448-P452 WeakPolarHBondContact O-CD 3.42Å; P452-T455 WeakPolarHBondContact CA-OG1 3.28Å; P452-T455 PolarHBondContact O-OG1 3.2Å; P452-G456 WeakPolarHBondContact O-CA 3.26Å; P452-G456 PolarHBondContact O-N 3.39Å
453	F	89.4	Confident	88.7	Confident	153 Å²	153	54.2 Å²	54.2	67%	0.671	29%	0.285	S	S	*	.	H	α-helix	trans	-71.1	-57.2	-178.7	-177.2	-97.7	0	0	0	111.1	D451 T455 G456 V457	D451-F453 PolarHBondContact O-N 2.92Å; F453-T455 PolarHBondContact O-N 3.26Å; F453-G456 PolarHBondContact O-N 3.38Å; F453-V457 HydrophobicContact CE1-CG2 4.25Å; F453-V457 HydrophobicContact CZ-CG2 4.27Å; F453-V457 WeakPolarHBondContact O-CG2 3.31Å; F453-V457 PolarHBondContact O-N 3.49Å
454	N	87	Confident	89	Confident	42 Å²	42	57.3 Å²	57.3	23%	0.225	30%	0.304	C	S	.	.	H	α-helix	trans	-66.4	-39.7	-177.2	-69.1	-47	0	0	0	111.5	S392 F396 D451 V457 G458	S392-N454 WeakPolarHBondContact CB-ND2 3.2Å; F396-N454 HydrophobicContact CB-CB 4.48Å; F396-N454 WeakPolarHBondContact CD2-O 3.31Å; D451-N454 VanDerWaalsContact CG-ND2 3.32Å; D451-N454 PolarHBondContact OD1-N 2.96Å; D451-N454 PolarHBondContact OD1-ND2 3.12Å; D451-N454 WeakPolarHBondContact OD2-CB 3.45Å; D451-N454 PolarHBondContact OD2-ND2 3.4Å; N454-V457 PolarHBondContact O-N 2.85Å; N454-G458 PolarHBondContact O-N 3.09Å
455	T	88.3	Confident	88.9	Confident	0 Å²	0	56.4 Å²	56.4	0%	0	30%	0.299	C	S	.	.	H	α-helix	trans	-66.9	-39.2	176.2	57.1	0	0	0	0	112.6	F399 S447 D451 P452 F453 G458 F459	F399-T455 HydrophobicContact CB-CG2 3.61Å; F399-T455 HydrophobicContact CD2-CG2 4.03Å; F399-T455 HydrophobicContact CG-CG2 3.85Å; S447-T455 WeakPolarHBondContact O-CG2 3.48Å; D451-T455 WeakPolarHBondContact O-CB 3.49Å; D451-T455 VanDerWaalsContact O-CG2 3.31Å; D451-T455 WeakPolarHBondContact O-CG2 3.27Å; D451-T455 PolarHBondContact O-N 3.44Å; D451-T455 VanDerWaalsContact O-N 3.15Å; D451-T455 PolarHBondContact O-OG1 3.07Å; P452-T455 WeakPolarHBondContact CA-OG1 3.28Å; P452-T455 PolarHBondContact O-OG1 3.2Å; F453-T455 PolarHBondContact O-N 3.26Å; T455-G458 PolarHBondContact O-N 3.35Å; T455-F459 PolarHBondContact O-N 3.3Å
456	G	90.2	Very high	89.1	Confident	32 Å²	32	53.1 Å²	53.1	33%	0.33	29%	0.286	S	S	.	.	H	α-helix	trans	-61.1	-43.8	173.5	0	0	0	0	0	112.5	P452 F453 F459 A460	P452-G456 WeakPolarHBondContact O-CA 3.26Å; P452-G456 PolarHBondContact O-N 3.39Å; F453-G456 PolarHBondContact O-N 3.38Å; G456-F459 PolarHBondContact O-N 2.91Å; G456-A460 WeakPolarHBondContact O-CB 3.29Å; G456-A460 PolarHBondContact O-N 3.43Å
457	V	90.4	Very high	89.4	Confident	60 Å²	60	55.9 Å²	55.9	36%	0.364	31%	0.305	S	S	.	.	H	α-helix	trans	-61.3	-46.3	173.7	172.7	0	0	0	0	110.8	F396 F453 N454 F459 A460 M461	F396-V457 HydrophobicContact CE2-CG1 4.45Å; F453-V457 HydrophobicContact CE1-CG2 4.25Å; F453-V457 HydrophobicContact CZ-CG2 4.27Å; F453-V457 WeakPolarHBondContact O-CG2 3.31Å; F453-V457 PolarHBondContact O-N 3.49Å; N454-V457 PolarHBondContact O-N 2.85Å; V457-F459 VanDerWaalsContact C-N 3.33Å; V457-F459 PolarHBondContact O-N 3.12Å; V457-A460 PolarHBondContact O-N 2.9Å; V457-M461 HydrophobicContact CG1-CG 4.36Å; V457-M461 HydrophobicContact CG1-SD 3.99Å; V457-M461 WeakPolarHBondContact O-CB 3.46Å; V457-M461 VanDerWaalsContact O-CG 3.29Å; V457-M461 WeakPolarHBondContact O-CG 3.12Å; V457-M461 PolarHBondContact O-N 3.03Å
458	G	88.9	Confident	89.5	Confident	0 Å²	0	56.1 Å²	56.1	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-59	-43.7	176.6	0	0	0	0	0	112.6	N454 T455 M461 S462	N454-G458 PolarHBondContact O-N 3.09Å; T455-G458 PolarHBondContact O-N 3.35Å; G458-M461 PolarHBondContact O-N 3.35Å; G458-S462 PolarHBondContact O-N 2.96Å
459	F	91.2	Very high	89.6	Confident	90 Å²	90	53.6 Å²	53.6	40%	0.395	29%	0.292	S	S	.	.	H	α-helix	trans	-62.9	-47.5	175.7	-169.7	-118.8	0	0	0	111.7	F399 L403 T455 G456 V457 M461 S462 L463	F399-F459 HydrophobicContact CE1-CB 3.74Å; F399-F459 HydrophobicContact CE1-CD2 4.03Å; F399-F459 HydrophobicContact CE1-CG 4.26Å; F399-F459 HydrophobicContact CZ-CB 4.08Å; F399-F459 HydrophobicContact CZ-CD2 4.13Å; F399-F459 HydrophobicContact CZ-CG 4.31Å; L403-F459 HydrophobicContact CD2-CD2 4.07Å; L403-F459 HydrophobicContact CD2-CE2 4.05Å; T455-F459 PolarHBondContact O-N 3.3Å; G456-F459 PolarHBondContact O-N 2.91Å; V457-F459 VanDerWaalsContact C-N 3.33Å; V457-F459 PolarHBondContact O-N 3.12Å; F459-M461 VanDerWaalsContact C-N 3.32Å; F459-M461 PolarHBondContact O-N 3.26Å; F459-S462 WeakPolarHBondContact O-CB 3.02Å; F459-S462 PolarHBondContact O-N 2.8Å; F459-S462 VanDerWaalsContact O-N 3.08Å; F459-S462 PolarHBondContact O-OG 3.16Å; F459-L463 HydrophobicContact CD1-CD1 3.95Å; F459-L463 HydrophobicContact CD1-CG 4.46Å; F459-L463 HydrophobicContact CE1-CD1 3.6Å; F459-L463 HydrophobicContact CE1-CG 4.2Å; F459-L463 HydrophobicContact CZ-CD1 4.08Å; F459-L463 HydrophobicContact CZ-CD2 4.21Å; F459-L463 HydrophobicContact CZ-CG 4.26Å; F459-L463 WeakPolarHBondContact O-CG 3.42Å; F459-L463 PolarHBondContact O-N 3.09Å
460	A	92.8	Very high	89.6	Confident	53 Å²	53	48.8 Å²	48.8	44%	0.438	27%	0.273	S	S	.	.	H	α-helix	trans	-58.1	-44.4	176.6	0	0	0	0	0	111.6	G456 V457 S462 L463 T464	G456-A460 WeakPolarHBondContact O-CB 3.29Å; G456-A460 PolarHBondContact O-N 3.43Å; V457-A460 PolarHBondContact O-N 2.9Å; A460-S462 VanDerWaalsContact C-N 3.33Å; A460-S462 PolarHBondContact O-N 2.92Å; A460-L463 PolarHBondContact O-N 3.39Å; A460-L463 VanDerWaalsContact O-N 3.13Å; A460-T464 WeakPolarHBondContact O-CG2 3.36Å; A460-T464 PolarHBondContact O-N 3.28Å; A460-T464 VanDerWaalsContact O-N 3.1Å
461	M	91.1	Very high	89.8	Confident	55 Å²	55	50.6 Å²	50.6	27%	0.271	28%	0.278	S	S	.	.	H	α-helix	trans	-59.5	-41.9	174.5	-71.9	176.9	73	0	0	111.9	I137 F396 V457 G458 F459 L463 T464	I137-M461 HydrophobicContact CB-CE 4.39Å; I137-M461 HydrophobicContact CG2-CE 3.41Å; I137-M461 VanDerWaalsContact CG2-CE 3.41Å; F396-M461 HydrophobicContact CE2-SD 4.05Å; F396-M461 HydrophobicContact CZ-SD 3.84Å; V457-M461 HydrophobicContact CG1-CG 4.36Å; V457-M461 HydrophobicContact CG1-SD 3.99Å; V457-M461 WeakPolarHBondContact O-CB 3.46Å; V457-M461 VanDerWaalsContact O-CG 3.29Å; V457-M461 WeakPolarHBondContact O-CG 3.12Å; V457-M461 PolarHBondContact O-N 3.03Å; G458-M461 PolarHBondContact O-N 3.35Å; F459-M461 VanDerWaalsContact C-N 3.32Å; F459-M461 PolarHBondContact O-N 3.26Å; M461-L463 VanDerWaalsContact C-N 3.32Å; M461-L463 PolarHBondContact O-N 3.32Å; M461-T464 PolarHBondContact O-N 3.26Å; M461-T464 PolarHBondContact O-OG1 2.91Å
462	S	91.4	Very high	89.6	Confident	2 Å²	2	55.4 Å²	55.4	1%	0.014	30%	0.298	C	S	.	.	H	α-helix	trans	-63.1	-38.3	175.3	77.1	0	0	0	0	112.4	G458 F459 A460 T464 G465	G458-S462 PolarHBondContact O-N 2.96Å; F459-S462 WeakPolarHBondContact O-CB 3.02Å; F459-S462 PolarHBondContact O-N 2.8Å; F459-S462 VanDerWaalsContact O-N 3.08Å; F459-S462 PolarHBondContact O-OG 3.16Å; A460-S462 VanDerWaalsContact C-N 3.33Å; A460-S462 PolarHBondContact O-N 2.92Å; S462-T464 VanDerWaalsContact C-N 3.29Å; S462-T464 PolarHBondContact O-N 3.45Å; S462-G465 PolarHBondContact O-N 2.76Å
463	L	92.9	Very high	89.2	Confident	71 Å²	71	53.7 Å²	53.7	37%	0.372	28%	0.284	S	S	.	.	H	α-helix	trans	-68.6	-24.9	178.1	-68.4	179.2	0	0	0	113.2	F459 A460 M461 G465 I466 P467	F459-L463 HydrophobicContact CD1-CD1 3.95Å; F459-L463 HydrophobicContact CD1-CG 4.46Å; F459-L463 HydrophobicContact CE1-CD1 3.6Å; F459-L463 HydrophobicContact CE1-CG 4.2Å; F459-L463 HydrophobicContact CZ-CD1 4.08Å; F459-L463 HydrophobicContact CZ-CD2 4.21Å; F459-L463 HydrophobicContact CZ-CG 4.26Å; F459-L463 WeakPolarHBondContact O-CG 3.42Å; F459-L463 PolarHBondContact O-N 3.09Å; A460-L463 PolarHBondContact O-N 3.39Å; A460-L463 VanDerWaalsContact O-N 3.13Å; M461-L463 VanDerWaalsContact C-N 3.32Å; M461-L463 PolarHBondContact O-N 3.32Å; L463-G465 PolarHBondContact O-N 3.26Å; L463-G465 VanDerWaalsContact O-N 3.09Å; L463-I466 HydrophobicContact CD2-CD1 3.87Å; L463-I466 WeakPolarHBondContact O-CB 3.38Å; L463-I466 WeakPolarHBondContact O-CG1 3.36Å; L463-I466 PolarHBondContact O-N 2.92Å; L463-P467 VanDerWaalsContact O-CD 3.31Å; L463-P467 WeakPolarHBondContact O-CD 3.42Å
464	T	94.5	Very high	88.7	Confident	66 Å²	66	53.1 Å²	53.1	41%	0.405	28%	0.278	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.9	-15.6	169.8	70.5	0	0	0	0	113	W133 A460 M461 S462 I466 P467 A468	W133-T464 PolarHBondContact NE1-OG1 3.47Å; A460-T464 WeakPolarHBondContact O-CG2 3.36Å; A460-T464 PolarHBondContact O-N 3.28Å; A460-T464 VanDerWaalsContact O-N 3.1Å; M461-T464 PolarHBondContact O-N 3.26Å; M461-T464 PolarHBondContact O-OG1 2.91Å; S462-T464 VanDerWaalsContact C-N 3.29Å; S462-T464 PolarHBondContact O-N 3.45Å; T464-I466 PolarHBondContact O-N 3.19Å; T464-P467 WeakPolarHBondContact O-CD 3.4Å; T464-P467 VanDerWaalsContact O-CG 3.26Å; T464-P467 WeakPolarHBondContact O-CG 3.29Å; T464-A468 WeakPolarHBondContact O-CB 3.22Å; T464-A468 PolarHBondContact O-N 2.96Å
465	G	91.1	Very high	87.9	Confident	0 Å²	0	57.1 Å²	57.1	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-64.3	-24.8	170.1	0	0	0	0	0	113.3	F129 W133 S462 L463 Y469	F129-G465 WeakPolarHBondContact CD1-O 3.45Å; F129-G465 VanDerWaalsContact CE1-O 3.27Å; F129-G465 WeakPolarHBondContact CE1-O 3.32Å; W133-G465 VanDerWaalsContact CD1-N 3.26Å; S462-G465 PolarHBondContact O-N 2.76Å; L463-G465 PolarHBondContact O-N 3.26Å; L463-G465 VanDerWaalsContact O-N 3.09Å; G465-Y469 VanDerWaalsContact O-CB 3.3Å; G465-Y469 WeakPolarHBondContact O-CB 3.37Å; G465-Y469 PolarHBondContact O-N 2.73Å
466	I	92.4	Very high	86.4	Confident	56 Å²	56	59.8 Å²	59.8	29%	0.287	31%	0.312	S	S	.	.	H	α-helix	trans	-66	-59.4	176.9	-60.1	170.8	0	0	0	111	I130 L463 T464 A468 Y469 Y470	I130-I466 HydrophobicContact CD1-CD1 4.34Å; I130-I466 HydrophobicContact CD1-CG1 3.62Å; I130-I466 HydrophobicContact CG1-CG1 4.03Å; L463-I466 HydrophobicContact CD2-CD1 3.87Å; L463-I466 WeakPolarHBondContact O-CB 3.38Å; L463-I466 WeakPolarHBondContact O-CG1 3.36Å; L463-I466 PolarHBondContact O-N 2.92Å; T464-I466 PolarHBondContact O-N 3.19Å; I466-A468 VanDerWaalsContact C-N 3.27Å; I466-A468 PolarHBondContact O-N 3.14Å; I466-Y469 WeakPolarHBondContact O-CB 3.32Å; I466-Y469 PolarHBondContact O-N 2.77Å; I466-Y470 HydrophobicContact CG2-CD2 4.03Å; I466-Y470 HydrophobicContact CG2-CE2 3.89Å; I466-Y470 VanDerWaalsContact O-CD2 3.25Å; I466-Y470 WeakPolarHBondContact O-CD2 3.46Å; I466-Y470 PolarHBondContact O-N 2.83Å
467	P	92	Very high	84.8	Confident	69 Å²	69	68.3 Å²	68.3	45%	0.448	34%	0.335	S	S	.	.	H	α-helix	trans	-61.4	-37.2	177.3	23	-32.3	0	0	0	111.7	L463 T464 Y469 Y470 I471	L463-P467 VanDerWaalsContact O-CD 3.31Å; L463-P467 WeakPolarHBondContact O-CD 3.42Å; T464-P467 WeakPolarHBondContact O-CD 3.4Å; T464-P467 VanDerWaalsContact O-CG 3.26Å; T464-P467 WeakPolarHBondContact O-CG 3.29Å; P467-Y469 PolarHBondContact O-N 2.91Å; P467-Y470 PolarHBondContact O-N 3.25Å; P467-I471 WeakPolarHBondContact O-CB 3.43Å; P467-I471 WeakPolarHBondContact O-CD1 3.29Å; P467-I471 VanDerWaalsContact O-CG1 3.24Å; P467-I471 WeakPolarHBondContact O-CG1 3.42Å; P467-I471 PolarHBondContact O-N 3.16Å
468	A	89.1	Confident	83	Confident	7 Å²	7	71.3 Å²	71.3	6%	0.058	36%	0.355	C	S	.	.	H	α-helix	trans	-60.5	-42.2	175.3	0	0	0	0	0	112.5	F129 W133 T464 I466 Y470 I471 F472	F129-A468 HydrophobicContact CE1-CB 3.93Å; F129-A468 HydrophobicContact CZ-CB 4.26Å; W133-A468 HydrophobicContact CD2-CB 4.25Å; W133-A468 HydrophobicContact CE3-CB 4.24Å; W133-A468 HydrophobicContact CH2-CB 3.8Å; W133-A468 HydrophobicContact CZ2-CB 3.77Å; W133-A468 HydrophobicContact CZ3-CB 4.03Å; T464-A468 WeakPolarHBondContact O-CB 3.22Å; T464-A468 PolarHBondContact O-N 2.96Å; I466-A468 VanDerWaalsContact C-N 3.27Å; I466-A468 PolarHBondContact O-N 3.14Å; A468-Y470 VanDerWaalsContact C-N 3.34Å; A468-Y470 PolarHBondContact O-N 2.66Å; A468-I471 PolarHBondContact O-N 3.38Å; A468-F472 HydrophobicContact CB-CD2 4.16Å; A468-F472 HydrophobicContact CB-CE2 4.37Å; A468-F472 WeakPolarHBondContact O-CB 3.44Å; A468-F472 VanDerWaalsContact O-CD2 3.23Å; A468-F472 WeakPolarHBondContact O-CD2 3.26Å; A468-F472 PolarHBondContact O-N 3.46Å
469	Y	88.9	Confident	81.4	Confident	27 Å²	27	73.9 Å²	73.9	11%	0.106	37%	0.373	C	S	.	.	H	α-helix	trans	-59.2	-45.7	175.2	178.4	-99.7	0	0	0	111.7	P125 Q126 F129 G465 I466 P467 I473 Y474	P125-Y469 HydrophobicContact CB-CE2 4.36Å; Q126-Y469 HydrophobicContact CB-CD1 4.26Å; Q126-Y469 HydrophobicContact CB-CE1 3.94Å; Q126-Y469 HydrophobicContact CB-CE2 4.48Å; Q126-Y469 HydrophobicContact CG-CD1 3.95Å; Q126-Y469 HydrophobicContact CG-CE1 4.11Å; Q126-Y469 HydrophobicContact CG-CG 4.36Å; F129-Y469 HydrophobicContact CB-CD2 3.49Å; F129-Y469 VanDerWaalsContact CB-CD2 3.49Å; F129-Y469 HydrophobicContact CB-CE2 4.12Å; F129-Y469 HydrophobicContact CB-CG 4.39Å; F129-Y469 AromaticContact CD1-CD2 3.94Å; F129-Y469 HydrophobicContact CD1-CD2 3.94Å; F129-Y469 HydrophobicContact CD1-CG 4.22Å; F129-Y469 HydrophobicContact CD2-CD2 4.3Å; F129-Y469 AromaticContact CG-CD2 3.64Å; F129-Y469 HydrophobicContact CG-CD2 3.64Å; F129-Y469 HydrophobicContact CG-CG 4.37Å; G465-Y469 VanDerWaalsContact O-CB 3.3Å; G465-Y469 WeakPolarHBondContact O-CB 3.37Å; G465-Y469 PolarHBondContact O-N 2.73Å; I466-Y469 WeakPolarHBondContact O-CB 3.32Å; I466-Y469 PolarHBondContact O-N 2.77Å; P467-Y469 PolarHBondContact O-N 2.91Å; Y469-I473 HydrophobicContact CD2-CB 4.11Å; Y469-I473 HydrophobicContact CD2-CD1 3.57Å; Y469-I473 HydrophobicContact CD2-CG1 4.42Å; Y469-I473 HydrophobicContact CD2-CG2 4.4Å; Y469-I473 HydrophobicContact CE2-CB 4.06Å; Y469-I473 HydrophobicContact CE2-CD1 3.88Å; Y469-I473 HydrophobicContact CE2-CG2 3.84Å; Y469-I473 WeakPolarHBondContact O-CA 3.48Å; Y469-I473 WeakPolarHBondContact O-CB 3.29Å; Y469-I473 PolarHBondContact O-N 3.27Å; Y469-Y474 PolarHBondContact O-N 2.68Å; Y469-Y474 VanDerWaalsContact O-N 3.08Å
470	Y	87.3	Confident	79.7	Confident	82 Å²	82	73.8 Å²	73.8	32%	0.322	38%	0.383	S	S	.	.	I	π-helix	trans	-65.7	-45.4	-179.7	-79.7	-73.3	0	0	0	111.4	I466 P467 A468 Y474 F475	I466-Y470 HydrophobicContact CG2-CD2 4.03Å; I466-Y470 HydrophobicContact CG2-CE2 3.89Å; I466-Y470 VanDerWaalsContact O-CD2 3.25Å; I466-Y470 WeakPolarHBondContact O-CD2 3.46Å; I466-Y470 PolarHBondContact O-N 2.83Å; P467-Y470 PolarHBondContact O-N 3.25Å; A468-Y470 VanDerWaalsContact C-N 3.34Å; A468-Y470 PolarHBondContact O-N 2.66Å; Y470-Y474 AromaticContact CD1-CD1 3.76Å; Y470-Y474 HydrophobicContact CD1-CD1 3.76Å; Y470-Y474 AromaticContact CD1-CG 3.8Å; Y470-Y474 HydrophobicContact CD1-CG 3.8Å; Y470-Y474 HydrophobicContact CE1-CD1 4.14Å; Y470-Y474 HydrophobicContact CE1-CD2 4.49Å; Y470-Y474 HydrophobicContact CE1-CG 4.09Å; Y470-Y474 PolarHBondContact O-N 3.07Å; Y470-F475 VanDerWaalsContact C-CD2 3.49Å; Y470-F475 HydrophobicContact CD1-CE2 4.29Å; Y470-F475 HydrophobicContact CG-CE2 4.44Å; Y470-F475 VanDerWaalsContact O-CB 3.27Å; Y470-F475 WeakPolarHBondContact O-CB 3.48Å; Y470-F475 WeakPolarHBondContact O-CD2 3.29Å; Y470-F475 WeakPolarHBondContact O-CG 3.5Å; Y470-F475 PolarHBondContact O-N 3.28Å
471	I	84.1	Confident	78.2	Confident	92 Å²	92	80.2 Å²	80.2	47%	0.472	40%	0.401	S	S	.	.	I	π-helix	trans	-63.8	-50.3	179.8	-67.7	165	0	0	0	111.5	P467 A468 S476	P467-I471 WeakPolarHBondContact O-CB 3.43Å; P467-I471 WeakPolarHBondContact O-CD1 3.29Å; P467-I471 VanDerWaalsContact O-CG1 3.24Å; P467-I471 WeakPolarHBondContact O-CG1 3.42Å; P467-I471 PolarHBondContact O-N 3.16Å; A468-I471 PolarHBondContact O-N 3.38Å; I471-S476 PolarHBondContact O-OG 3.11Å
472	F	79.3	Confident	76.9	Confident	126 Å²	126	80.9 Å²	80.9	55%	0.553	41%	0.405	S	S	*	.	I	π-helix	trans	-91.4	-24.9	-168.7	-66.9	-63	0	0	0	114.7	A468 S476	A468-F472 HydrophobicContact CB-CD2 4.16Å; A468-F472 HydrophobicContact CB-CE2 4.37Å; A468-F472 WeakPolarHBondContact O-CB 3.44Å; A468-F472 VanDerWaalsContact O-CD2 3.23Å; A468-F472 WeakPolarHBondContact O-CD2 3.26Å; A468-F472 PolarHBondContact O-N 3.46Å; F472-S476 WeakPolarHBondContact O-CB 3.2Å; F472-S476 PolarHBondContact O-OG 3.34Å
473	I	81	Confident	75.7	Confident	45 Å²	45	83 Å²	83	23%	0.231	42%	0.419	C	S	.	.	I	π-helix	trans	-117.7	-52.1	-173.1	-62.8	162.7	0	0	0	111.1	F129 Q355 Y469	F129-I473 HydrophobicContact CB-CD1 4.5Å; F129-I473 HydrophobicContact CD2-CD1 3.26Å; F129-I473 HydrophobicContact CE2-CD1 3.48Å; F129-I473 VanDerWaalsContact CE2-CD1 3.48Å; F129-I473 HydrophobicContact CG-CD1 3.93Å; F129-I473 HydrophobicContact CZ-CD1 4.29Å; Q355-I473 HydrophobicContact CB-CD1 3.94Å; Q355-I473 HydrophobicContact CG-CD1 3.93Å; Y469-I473 HydrophobicContact CD2-CB 4.11Å; Y469-I473 HydrophobicContact CD2-CD1 3.57Å; Y469-I473 HydrophobicContact CD2-CG1 4.42Å; Y469-I473 HydrophobicContact CD2-CG2 4.4Å; Y469-I473 HydrophobicContact CE2-CB 4.06Å; Y469-I473 HydrophobicContact CE2-CD1 3.88Å; Y469-I473 HydrophobicContact CE2-CG2 3.84Å; Y469-I473 WeakPolarHBondContact O-CA 3.48Å; Y469-I473 WeakPolarHBondContact O-CB 3.29Å; Y469-I473 PolarHBondContact O-N 3.27Å
474	Y	79	Confident	74.6	Confident	141 Å²	141	83.7 Å²	83.7	55%	0.553	43%	0.427	S	S	*	.	I	π-helix	trans	-72.7	-45.9	-174.9	-172.7	-97.3	0	0	0	112.5	Y469 Y470	Y469-Y474 PolarHBondContact O-N 2.68Å; Y469-Y474 VanDerWaalsContact O-N 3.08Å; Y470-Y474 AromaticContact CD1-CD1 3.76Å; Y470-Y474 HydrophobicContact CD1-CD1 3.76Å; Y470-Y474 AromaticContact CD1-CG 3.8Å; Y470-Y474 HydrophobicContact CD1-CG 3.8Å; Y470-Y474 HydrophobicContact CE1-CD1 4.14Å; Y470-Y474 HydrophobicContact CE1-CD2 4.49Å; Y470-Y474 HydrophobicContact CE1-CG 4.09Å; Y470-Y474 PolarHBondContact O-N 3.07Å
475	F	70.1	Confident	73.6	Confident	125 Å²	125	84.1 Å²	84.1	55%	0.548	43%	0.431	S	S	.	.	S	Bend	trans	-84.8	-11.7	-178.4	-67.9	-53.9	0	0	0	113.9	Y470 R477	Y470-F475 VanDerWaalsContact C-CD2 3.49Å; Y470-F475 HydrophobicContact CD1-CE2 4.29Å; Y470-F475 HydrophobicContact CG-CE2 4.44Å; Y470-F475 VanDerWaalsContact O-CB 3.27Å; Y470-F475 WeakPolarHBondContact O-CB 3.48Å; Y470-F475 WeakPolarHBondContact O-CD2 3.29Å; Y470-F475 WeakPolarHBondContact O-CG 3.5Å; Y470-F475 PolarHBondContact O-N 3.28Å; F475-R477 PolarHBondContact O-N 2.94Å
476	S	57.8	Low	72.6	Confident	56 Å²	56	87 Å²	87	39%	0.392	45%	0.448	S	S	.	.			trans	-71.9	22.6	177.2	-63.9	0	0	0	0	115.1	I471 F472	I471-S476 PolarHBondContact O-OG 3.11Å; F472-S476 WeakPolarHBondContact O-CB 3.2Å; F472-S476 PolarHBondContact O-OG 3.34Å
477	R	56.4	Low	71.8	Confident	212 Å²	212	89.2 Å²	89.2	80%	0.8	46%	0.461	S	S	*	.	S	Bend	trans	-71.6	146	156.9	-77.3	-167.8	174.9	174.5	1.5	108.9	F475 S479	F475-R477 PolarHBondContact O-N 2.94Å; R477-S479 PolarHBondContact O-N 3.31Å
478	P	51.6	Low	71.2	Confident	123 Å²	123	89.3 Å²	89.3	80%	0.799	46%	0.463	S	S	*	.	S	Bend	trans	-75.4	80.4	-136.3	34.2	-37	0	0	0	112.4
479	S	55.3	Low	70.8	Confident	53 Å²	53	94.8 Å²	94.8	37%	0.371	49%	0.486	S	S	.	.			trans	-81.3	114.8	156.7	39	0	0	0	0	107.2	R477 F481 I482 S483	R477-S479 PolarHBondContact O-N 3.31Å; S479-F481 PolarHBondContact O-N 3.34Å; S479-I482 PolarHBondContact O-N 2.63Å; S479-S483 PolarHBondContact O-N 3.5Å
480	C	56.2	Low	70.4	Confident	89 Å²	89	94.6 Å²	94.6	60%	0.601	49%	0.487	S	S	*	.	H	α-helix	trans	-45.3	-30.2	178.4	-176.6	0	0	0	0	112.9	I482 V484	C480-I482 VanDerWaalsContact C-N 3.33Å; C480-I482 PolarHBondContact O-N 3.45Å; C480-V484 WeakPolarHBondContact O-CB 3.45Å; C480-V484 WeakPolarHBondContact O-CG2 3.16Å; C480-V484 PolarHBondContact O-N 2.87Å
481	F	60.9	Low	70.1	Confident	188 Å²	188	99.2 Å²	99.2	83%	0.825	50%	0.504	S	S	*	.	H	α-helix	trans	-60.6	-28.8	177.1	-81.6	-82.8	0	0	0	115.7	S479 P485	S479-F481 PolarHBondContact O-N 3.34Å; F481-P485 VanDerWaalsContact O-CD 3.24Å; F481-P485 WeakPolarHBondContact O-CD 3.35Å; F481-P485 VanDerWaalsContact O-CG 3.26Å; F481-P485 WeakPolarHBondContact O-CG 3.46Å
482	I	64.4	Low	70.1	Confident	69 Å²	69	98 Å²	98	35%	0.354	50%	0.5	S	S	.	.	H	α-helix	trans	-103.7	-35.1	-178.7	-60.1	175.8	0	0	0	111.1	S479 C480 P485 T486	S479-I482 PolarHBondContact O-N 2.63Å; C480-I482 VanDerWaalsContact C-N 3.33Å; C480-I482 PolarHBondContact O-N 3.45Å; I482-P485 WeakPolarHBondContact O-CD 3.34Å; I482-T486 WeakPolarHBondContact O-CB 3.05Å; I482-T486 PolarHBondContact O-N 3.17Å; I482-T486 PolarHBondContact O-OG1 3.49Å
483	S	65.4	Low	70.2	Confident	45 Å²	45	94.1 Å²	94.1	32%	0.315	48%	0.484	S	S	.	.	H	α-helix	trans	-68.8	-43.1	-178.5	60.6	0	0	0	0	112.5	S479 T486 D487	S479-S483 PolarHBondContact O-N 3.5Å; S483-T486 PolarHBondContact O-N 3.14Å; S483-D487 WeakPolarHBondContact O-CB 3.44Å; S483-D487 PolarHBondContact O-N 2.87Å
484	V	69.2	Low	70.3	Confident	86 Å²	86	95 Å²	95	52%	0.521	49%	0.488	S	S	.	.	H	α-helix	trans	-64.1	-46.6	-177.1	175.4	0	0	0	0	112.8	C480 T486 S488	C480-V484 WeakPolarHBondContact O-CB 3.45Å; C480-V484 WeakPolarHBondContact O-CG2 3.16Å; C480-V484 PolarHBondContact O-N 2.87Å; V484-T486 VanDerWaalsContact C-N 3.34Å; V484-T486 PolarHBondContact O-N 3.36Å; V484-S488 VanDerWaalsContact O-CB 3.3Å; V484-S488 WeakPolarHBondContact O-CB 3.36Å; V484-S488 PolarHBondContact O-N 3.42Å
485	P	74.1	Confident	70.6	Confident	76 Å²	76	93.8 Å²	93.8	49%	0.494	49%	0.489	S	S	.	.	H	α-helix	trans	-64.8	-37.5	174.9	-21.6	33.1	0	0	0	112.9	F481 I482 S488 F489	F481-P485 VanDerWaalsContact O-CD 3.24Å; F481-P485 WeakPolarHBondContact O-CD 3.35Å; F481-P485 VanDerWaalsContact O-CG 3.26Å; F481-P485 WeakPolarHBondContact O-CG 3.46Å; I482-P485 WeakPolarHBondContact O-CD 3.34Å; P485-S488 PolarHBondContact O-N 3.29Å; P485-F489 VanDerWaalsContact O-CB 3.26Å; P485-F489 WeakPolarHBondContact O-CB 3.44Å; P485-F489 PolarHBondContact O-N 2.89Å
486	T	70.9	Confident	71.3	Confident	59 Å²	59	93.2 Å²	93.2	36%	0.362	49%	0.491	S	S	.	.	H	α-helix	trans	-68.5	-43.5	-179.3	-53.7	0	0	0	0	111.1	I482 S483 V484 F489 N490	I482-T486 WeakPolarHBondContact O-CB 3.05Å; I482-T486 PolarHBondContact O-N 3.17Å; I482-T486 PolarHBondContact O-OG1 3.49Å; S483-T486 PolarHBondContact O-N 3.14Å; V484-T486 VanDerWaalsContact C-N 3.34Å; V484-T486 PolarHBondContact O-N 3.36Å; T486-F489 PolarHBondContact O-N 2.85Å; T486-N490 WeakPolarHBondContact O-CB 3.39Å; T486-N490 VanDerWaalsContact O-CG 3.23Å; T486-N490 PolarHBondContact O-N 2.94Å; T486-N490 PolarHBondContact O-ND2 2.99Å
487	D	75.4	Confident	72.5	Confident	103 Å²	103	91.5 Å²	91.5	55%	0.551	48%	0.477	S	S	*	.	H	α-helix	trans	-66.6	-40.3	175.3	-72.4	-16.5	0	0	0	111.5	S483 N490 R491	S483-D487 WeakPolarHBondContact O-CB 3.44Å; S483-D487 PolarHBondContact O-N 2.87Å; D487-N490 PolarHBondContact O-N 2.95Å; D487-R491 WeakPolarHBondContact O-CB 3.35Å; D487-R491 PolarHBondContact O-N 3.38Å
488	S	79.6	Confident	73.8	Confident	71 Å²	71	85.2 Å²	85.2	50%	0.497	46%	0.457	S	S	.	.	H	α-helix	trans	-63.6	-41.9	173.9	-171.2	0	0	0	0	111.8	V484 P485 T492	V484-S488 VanDerWaalsContact O-CB 3.3Å; V484-S488 WeakPolarHBondContact O-CB 3.36Å; V484-S488 PolarHBondContact O-N 3.42Å; P485-S488 PolarHBondContact O-N 3.29Å; S488-T492 WeakPolarHBondContact O-CB 3.38Å; S488-T492 PolarHBondContact O-N 3.48Å; S488-T492 PolarHBondContact O-OG1 3.19Å
489	F	80.8	Confident	75.2	Confident	123 Å²	123	79.5 Å²	79.5	54%	0.539	42%	0.42	S	S	.	.	H	α-helix	trans	-63.5	-46	175.6	176.3	-97.7	0	0	0	110.5	P485 T486 R491 T492 M493	P485-F489 VanDerWaalsContact O-CB 3.26Å; P485-F489 WeakPolarHBondContact O-CB 3.44Å; P485-F489 PolarHBondContact O-N 2.89Å; T486-F489 PolarHBondContact O-N 2.85Å; F489-R491 PolarHBondContact O-N 2.82Å; F489-T492 PolarHBondContact O-N 3.08Å; F489-M493 HydrophobicContact CD1-CG 4.17Å; F489-M493 HydrophobicContact CD2-CG 4.33Å; F489-M493 HydrophobicContact CE1-CG 3.7Å; F489-M493 HydrophobicContact CE2-CE 4.2Å; F489-M493 HydrophobicContact CE2-CG 3.89Å; F489-M493 HydrophobicContact CE2-SD 4.29Å; F489-M493 HydrophobicContact CG-CG 4.47Å; F489-M493 HydrophobicContact CZ-CG 3.55Å; F489-M493 HydrophobicContact CZ-SD 4.08Å; F489-M493 WeakPolarHBondContact O-CB 3.4Å; F489-M493 WeakPolarHBondContact O-CG 3.28Å; F489-M493 PolarHBondContact O-N 2.98Å
490	N	79.1	Confident	76.4	Confident	23 Å²	23	80 Å²	80	12%	0.123	42%	0.42	C	S	.	.	H	α-helix	trans	-60.1	-47	179.5	-77.6	-22.1	0	0	0	111.3	V359 T486 D487 M493 Q494	V359-N490 HydrophobicContact CG2-CB 3.6Å; V359-N490 WeakPolarHBondContact CG2-OD1 3.48Å; T486-N490 WeakPolarHBondContact O-CB 3.39Å; T486-N490 VanDerWaalsContact O-CG 3.23Å; T486-N490 PolarHBondContact O-N 2.94Å; T486-N490 PolarHBondContact O-ND2 2.99Å; D487-N490 PolarHBondContact O-N 2.95Å; N490-M493 PolarHBondContact O-N 3.4Å; N490-Q494 VanDerWaalsContact O-CB 3.27Å; N490-Q494 WeakPolarHBondContact O-CB 3.47Å; N490-Q494 PolarHBondContact O-N 2.63Å
491	R	81.5	Confident	77.2	Confident	179 Å²	179	78.8 Å²	78.8	68%	0.675	41%	0.412	S	S	*	.	H	α-helix	trans	-63.4	-42.2	177.1	-172	178.8	177	-151.6	-1	112.3	D487 F489 Q494 I495	D487-R491 WeakPolarHBondContact O-CB 3.35Å; D487-R491 PolarHBondContact O-N 3.38Å; F489-R491 PolarHBondContact O-N 2.82Å; R491-Q494 WeakPolarHBondContact O-CB 3.37Å; R491-Q494 PolarHBondContact O-N 3.2Å; R491-I495 HydrophobicContact CG-CD1 4.17Å; R491-I495 VanDerWaalsContact O-CG1 3.31Å; R491-I495 WeakPolarHBondContact O-CG1 3.32Å; R491-I495 PolarHBondContact O-N 3.47Å
492	T	84.6	Confident	77.3	Confident	65 Å²	65	71 Å²	71	40%	0.399	38%	0.382	S	S	.	.	H	α-helix	trans	-62.9	-46.9	176.8	-61.9	0	0	0	0	111.2	S488 F489 Q494 I495 I496	S488-T492 WeakPolarHBondContact O-CB 3.38Å; S488-T492 PolarHBondContact O-N 3.48Å; S488-T492 PolarHBondContact O-OG1 3.19Å; F489-T492 PolarHBondContact O-N 3.08Å; T492-Q494 VanDerWaalsContact C-N 3.3Å; T492-Q494 PolarHBondContact O-N 2.96Å; T492-I495 PolarHBondContact O-N 3.13Å; T492-I496 HydrophobicContact CG2-CD1 3.71Å; T492-I496 HydrophobicContact CG2-CG1 4.44Å; T492-I496 WeakPolarHBondContact O-CB 3.49Å; T492-I496 VanDerWaalsContact O-CG1 3.3Å; T492-I496 WeakPolarHBondContact O-CG1 3.37Å; T492-I496 PolarHBondContact O-N 3.13Å
493	M	81.4	Confident	76.8	Confident	45 Å²	45	75 Å²	75	22%	0.222	40%	0.404	C	S	.	.	H	α-helix	trans	-62.6	-38.4	175.3	-73.1	-62.7	106.6	0	0	111.7	V359 F489 N490 I495 I496 L497	V359-M493 HydrophobicContact CG1-CB 3.86Å; F489-M493 HydrophobicContact CD1-CG 4.17Å; F489-M493 HydrophobicContact CD2-CG 4.33Å; F489-M493 HydrophobicContact CE1-CG 3.7Å; F489-M493 HydrophobicContact CE2-CE 4.2Å; F489-M493 HydrophobicContact CE2-CG 3.89Å; F489-M493 HydrophobicContact CE2-SD 4.29Å; F489-M493 HydrophobicContact CG-CG 4.47Å; F489-M493 HydrophobicContact CZ-CG 3.55Å; F489-M493 HydrophobicContact CZ-SD 4.08Å; F489-M493 WeakPolarHBondContact O-CB 3.4Å; F489-M493 WeakPolarHBondContact O-CG 3.28Å; F489-M493 PolarHBondContact O-N 2.98Å; N490-M493 PolarHBondContact O-N 3.4Å; M493-I495 VanDerWaalsContact C-N 3.35Å; M493-I495 PolarHBondContact O-N 3.12Å; M493-I496 HydrophobicContact CE-CD1 3.96Å; M493-I496 PolarHBondContact O-N 3.1Å; M493-L497 HydrophobicContact CB-CD1 4.46Å; M493-L497 WeakPolarHBondContact O-CB 3.3Å; M493-L497 VanDerWaalsContact O-CG 3.22Å; M493-L497 WeakPolarHBondContact O-CG 3.43Å; M493-L497 PolarHBondContact O-N 3.19Å
494	Q	83.5	Confident	75.5	Confident	64 Å²	64	83.5 Å²	83.5	30%	0.299	44%	0.439	S	S	.	.	H	α-helix	trans	-60.3	-44.5	177.4	-164.6	-179.7	-1	0	0	112.1	M362 N490 R491 T492 E498 V499	M362-Q494 HydrophobicContact SD-CG 3.97Å; N490-Q494 VanDerWaalsContact O-CB 3.27Å; N490-Q494 WeakPolarHBondContact O-CB 3.47Å; N490-Q494 PolarHBondContact O-N 2.63Å; R491-Q494 WeakPolarHBondContact O-CB 3.37Å; R491-Q494 PolarHBondContact O-N 3.2Å; T492-Q494 VanDerWaalsContact C-N 3.3Å; T492-Q494 PolarHBondContact O-N 2.96Å; Q494-E498 WeakPolarHBondContact O-CA 3.36Å; Q494-E498 PolarHBondContact O-N 3.29Å; Q494-E498 VanDerWaalsContact O-N 3.12Å; Q494-V499 HydrophobicContact CB-CG2 4.46Å; Q494-V499 HydrophobicContact CG-CG2 4.17Å; Q494-V499 WeakPolarHBondContact CG-O 3.32Å; Q494-V499 PolarHBondContact NE2-O 3.18Å; Q494-V499 PolarHBondContact O-N 3.14Å
495	I	83.8	Confident	75.9	Confident	115 Å²	115	83.4 Å²	83.4	59%	0.59	43%	0.434	S	S	*	.	H	α-helix	trans	-68.7	-48	178.2	-65.4	165.3	0	0	0	110.9	R491 T492 M493 L497 E498	R491-I495 HydrophobicContact CG-CD1 4.17Å; R491-I495 VanDerWaalsContact O-CG1 3.31Å; R491-I495 WeakPolarHBondContact O-CG1 3.32Å; R491-I495 PolarHBondContact O-N 3.47Å; T492-I495 PolarHBondContact O-N 3.13Å; M493-I495 VanDerWaalsContact C-N 3.35Å; M493-I495 PolarHBondContact O-N 3.12Å; I495-L497 VanDerWaalsContact C-N 3.31Å; I495-L497 PolarHBondContact O-N 3.15Å; I495-E498 PolarHBondContact O-N 2.92Å
496	I	85.5	Confident	75.9	Confident	114 Å²	114	83.7 Å²	83.7	59%	0.585	43%	0.431	S	S	*	.	H	α-helix	trans	-63.2	-39.5	-177.8	-70.2	172.7	0	0	0	111.4	T492 M493	T492-I496 HydrophobicContact CG2-CD1 3.71Å; T492-I496 HydrophobicContact CG2-CG1 4.44Å; T492-I496 WeakPolarHBondContact O-CB 3.49Å; T492-I496 VanDerWaalsContact O-CG1 3.3Å; T492-I496 WeakPolarHBondContact O-CG1 3.37Å; T492-I496 PolarHBondContact O-N 3.13Å; M493-I496 HydrophobicContact CE-CD1 3.96Å; M493-I496 PolarHBondContact O-N 3.1Å
497	L	81.9	Confident	76.2	Confident	19 Å²	19	85.1 Å²	85.1	10%	0.099	44%	0.435	C	S	.	.	H	α-helix	trans	-92.3	-3.3	-174.1	-58.7	177.9	0	0	0	113.5	H364 L371 A372 L375 M493 I495 V499	H364-L497 PolarHBondContact CD2-O 3.41Å; L371-L497 HydrophobicContact CD2-CB 4.09Å; L371-L497 HydrophobicContact CD2-CD2 3.77Å; L371-L497 HydrophobicContact CD2-CG 4.46Å; L371-L497 HydrophobicContact CG-CD2 4.2Å; A372-L497 HydrophobicContact CB-CD1 4.07Å; L375-L497 HydrophobicContact CD1-CD1 4.04Å; L375-L497 HydrophobicContact CD1-CD2 3.43Å; L375-L497 VanDerWaalsContact CD1-CD2 3.43Å; L375-L497 HydrophobicContact CD1-CG 4.4Å; M493-L497 HydrophobicContact CB-CD1 4.46Å; M493-L497 WeakPolarHBondContact O-CB 3.3Å; M493-L497 VanDerWaalsContact O-CG 3.22Å; M493-L497 WeakPolarHBondContact O-CG 3.43Å; M493-L497 PolarHBondContact O-N 3.19Å; I495-L497 VanDerWaalsContact C-N 3.31Å; I495-L497 PolarHBondContact O-N 3.15Å; L497-V499 HydrophobicContact CB-CB 4.48Å; L497-V499 HydrophobicContact CB-CG1 3.73Å; L497-V499 HydrophobicContact CB-CG2 4.09Å; L497-V499 WeakPolarHBondContact O-CG1 3.29Å; L497-V499 PolarHBondContact O-N 2.95Å
498	E	83.8	Confident	76.3	Confident	81 Å²	81	84.1 Å²	84.1	38%	0.379	43%	0.428	S	S	.	.	T	Hydrogen-bonded Turn	trans	46.2	46.7	-171.3	-63.9	-172.2	173.9	0	0	112.1	H364 V365 R366 Q494 I495	H364-E498 IonicContact CE1-OE2 3.54Å; V365-E498 WeakPolarHBondContact CG2-O 3.48Å; V365-E498 PolarHBondContact N-O 2.98Å; R366-E498 IonicContact CZ-OE1 2.73Å; R366-E498 IonicContact CZ-OE2 2.81Å; R366-E498 IonicContact NE-OE2 2.96Å; R366-E498 PolarHBondContact NE-OE2 3.39Å; R366-E498 VanDerWaalsContact NH2-CD 3.33Å; R366-E498 IonicContact NH2-OE1 3.42Å; R366-E498 PolarHBondContact NH2-OE1 2.89Å; R366-E498 IonicContact NH2-OE2 3.19Å; R366-E498 PolarHBondContact NH2-OE2 2.98Å; Q494-E498 WeakPolarHBondContact O-CA 3.36Å; Q494-E498 PolarHBondContact O-N 3.29Å; Q494-E498 VanDerWaalsContact O-N 3.12Å; I495-E498 PolarHBondContact O-N 2.92Å
499	V	81.5	Confident	76.1	Confident	3 Å²	3	84.9 Å²	84.9	2%	0.018	42%	0.424	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.7	149.3	-178.4	-63.3	0	0	0	0	111.7	M362 I363 H364 L371 Q494 L497	M362-V499 HydrophobicContact CB-CB 3.73Å; M362-V499 HydrophobicContact CB-CG2 3.74Å; M362-V499 HydrophobicContact CG-CG2 4.45Å; M362-V499 HydrophobicContact SD-CG2 3.9Å; I363-V499 CarbonylContact O-C 3.51Å; I363-V499 WeakPolarHBondContact O-CA 3.48Å; H364-V499 HydrophobicContact CB-CG1 4.28Å; L371-V499 HydrophobicContact CB-CG1 4.44Å; Q494-V499 HydrophobicContact CB-CG2 4.46Å; Q494-V499 HydrophobicContact CG-CG2 4.17Å; Q494-V499 WeakPolarHBondContact CG-O 3.32Å; Q494-V499 PolarHBondContact NE2-O 3.18Å; Q494-V499 PolarHBondContact O-N 3.14Å; L497-V499 HydrophobicContact CB-CB 4.48Å; L497-V499 HydrophobicContact CB-CG1 3.73Å; L497-V499 HydrophobicContact CB-CG2 4.09Å; L497-V499 WeakPolarHBondContact O-CG1 3.29Å; L497-V499 PolarHBondContact O-N 2.95Å
500	V	80.1	Confident	75.7	Confident	63 Å²	63	82.3 Å²	82.3	38%	0.382	42%	0.416	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-127	149.1	175.3	-71.2	0	0	0	0	109.9	M362 I363 V365 A502	M362-V500 CarbonylContact C-O 3.4Å; M362-V500 VanDerWaalsContact CA-O 3.3Å; M362-V500 WeakPolarHBondContact CA-O 3.46Å; M362-V500 VanDerWaalsContact CB-O 3.29Å; M362-V500 WeakPolarHBondContact CB-O 3.46Å; I363-V500 PolarHBondContact N-O 3.14Å; I363-V500 PolarHBondContact O-N 2.92Å; V365-V500 HydrophobicContact CG2-CB 4.27Å; V365-V500 HydrophobicContact CG2-CG1 3.54Å; V365-V500 HydrophobicContact CG2-CG2 3.8Å; V500-A502 PolarHBondContact O-N 3.25Å
501	P	74.1	Confident	75.5	Confident	64 Å²	64	86.6 Å²	86.6	42%	0.416	44%	0.437	S	S	.	.	P	Polyproline II helix	trans	-51.4	140	166.5	-19.3	29.9	0	0	0	109.4	M362 D503	M362-P501 HydrophobicContact CE-CG 4.17Å; P501-D503 PolarHBondContact O-N 3.01Å
502	A	62.9	Low	75.1	Confident	25 Å²	25	79.5 Å²	79.5	21%	0.207	42%	0.419	C	S	.	.	P	Polyproline II helix	trans	-65	129.3	168.8	0	0	0	0	0	107.9	Y348 I363 V500 Q504	Y348-A502 HydrophobicContact CE2-CB 3.73Å; I363-A502 HydrophobicContact CD1-CB 3.82Å; I363-A502 HydrophobicContact CG1-CB 4.43Å; V500-A502 PolarHBondContact O-N 3.25Å; A502-Q504 PolarHBondContact O-N 2.7Å
503	D	53.6	Low	74.3	Confident	151 Å²	151	80.7 Å²	80.7	81%	0.807	42%	0.421	S	S	*	.	P	Polyproline II helix	trans	-54.5	125	178.9	-69.3	-39.4	0	0	0	109.9	P501	P501-D503 PolarHBondContact O-N 3.01Å
504	Q	39.1	Very low	73.6	Confident	224 Å²	224	83.9 Å²	83.9	100%	1.047	44%	0.439	S	S	*	.			trans	-74.9	0	-171.7	-70.5	-175.1	-9.2	0	0	113.8	A502	A502-Q504 PolarHBondContact O-N 2.7Å

Retrieved 504 of 504 residues in 111.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).