A0A087X4X7_POEFO Loading...

Steroid sulfatase

AlphaFold DB , UniProt , Accession A0A087X4X7, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 575 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M40.1Very low47.2Very low249 Ų249154.7 Ų154.7100%1.22783%0.834SS**  099.20-72.7167.196.800107.5
2M38.4Very low47.7Very low198 Ų198152.5 Ų152.598%0.97582%0.82SS**PPolyproline II helixtrans-87.7120.8173.1-75.9157.47400107.6
3S38.6Very low48Very low121 Ų121149.2 Ų149.285%0.84680%0.801SS**PPolyproline II helixtrans-97.3121.3166.846.50000109.1
4A43.6Very low48.2Very low97 Ų97148 Ų14880%0.80279%0.79SS**PPolyproline II helixtrans-77135.5-176.200000111.8
5L46.9Very low48.3Very low175 Ų175146.3 Ų146.392%0.91678%0.781SS**PPolyproline II helixtrans-77.5119.1163.2-85.8137.8000108.8
6M49.4Very low48.4Very low176 Ų176144.4 Ų144.487%0.86777%0.77SS**PPolyproline II helixtrans-79.4134.8169.4-73.9-174.5172.500110.5
7P46.6Very low48.4Very low122 Ų122143.5 Ų143.579%0.79276%0.764SS**PPolyproline II helixtrans-81.9139.817230.4-27.4000111.5
8H53Low48.3Very low149 Ų149141.6 Ų141.669%0.6976%0.759SS**PPolyproline II helixtrans-65.4135.8-177.3-9415.8000113.5Y10 L11H8-Y10 PolarHBondContact O-N 3.41Å; H8-Y10 VanDerWaalsContact O-N 3.13Å; H8-L11 PolarHBondContact O-N 3.13Å
9P55.6Low48Very low100 Ų100137.1 Ų137.165%0.64975%0.749SS**Hα-helixtrans-68.7-11.2-176.426.4-33.6000114.9
10Y53.8Low47.6Very low185 Ų185139.5 Ų139.573%0.72575%0.752SS**Hα-helixtrans-82.1-22.5-179.3-67.8-78.3000114H8 M14H8-Y10 PolarHBondContact O-N 3.41Å; H8-Y10 VanDerWaalsContact O-N 3.13Å; Y10-M14 PolarHBondContact O-N 3.21Å
11L53.2Low47.1Very low130 Ų130137.6 Ų137.668%0.68175%0.749SS**Hα-helixtrans-76.1-31.8-179.9-153.476000111.7H8 L15H8-L11 PolarHBondContact O-N 3.13Å; L11-L15 PolarHBondContact O-N 3.45Å
12L53.1Low47.1Very low128 Ų128131.5 Ų131.567%0.6773%0.726SS**Hα-helixtrans-71.4-32.8178-148.781.7000112.1L16L12-L16 WeakPolarHBondContact O-CD1 3.36Å; L12-L16 WeakPolarHBondContact O-CG 3.44Å; L12-L16 PolarHBondContact O-N 3.28Å; L12-L16 VanDerWaalsContact O-N 3.11Å
13L51.7Low47.2Very low109 Ų109129.2 Ų129.257%0.57172%0.716SS**Hα-helixtrans-74.2-34.2179.1-155.176.1000112.3L16 L17L13-L16 PolarHBondContact O-N 3.47Å; L13-L17 PolarHBondContact O-N 3.48Å
14M50.5Low47.2Very low133 Ų133131.2 Ų131.266%0.65572%0.717SS**Hα-helixtrans-69.2-38.2172.2-90.8-77.5-142.400112.3Y10 L16 L17 V18Y10-M14 PolarHBondContact O-N 3.21Å; M14-L16 VanDerWaalsContact C-N 3.32Å; M14-L16 PolarHBondContact O-N 3.11Å; M14-L17 PolarHBondContact O-N 3.04Å; M14-V18 WeakPolarHBondContact O-CG2 3.34Å; M14-V18 PolarHBondContact O-N 3.31Å
15L50.6Low46.9Very low123 Ų123134.2 Ų134.264%0.64471%0.714SS**Hα-helixtrans-68.5-29.1174.5-96.2141.6000113.1L11 G19L11-L15 PolarHBondContact O-N 3.45Å; L15-G19 PolarHBondContact O-N 3.23Å
16L49.6Very low46.8Very low116 Ų116133.4 Ų133.461%0.60771%0.706SS**Hα-helixtrans-77.1-21.3173.9-76.7163.1000113.6L12 L13 M14L12-L16 WeakPolarHBondContact O-CD1 3.36Å; L12-L16 WeakPolarHBondContact O-CG 3.44Å; L12-L16 PolarHBondContact O-N 3.28Å; L12-L16 VanDerWaalsContact O-N 3.11Å; L13-L16 PolarHBondContact O-N 3.47Å; M14-L16 VanDerWaalsContact C-N 3.32Å; M14-L16 PolarHBondContact O-N 3.11Å
17L48.5Very low47.2Very low128 Ų128132.6 Ų132.667%0.6771%0.705SS**Hα-helixtrans-89.9-27.3175.1-80.3159.3000113L13 M14L13-L17 PolarHBondContact O-N 3.48Å; M14-L17 PolarHBondContact O-N 3.04Å
18V47.1Very low48.8Very low110 Ų110132.4 Ų132.467%0.66770%0.696SS**Hα-helixtrans-82.6-17.4175.2177.30000112.3M14 K20M14-V18 WeakPolarHBondContact O-CG2 3.34Å; M14-V18 PolarHBondContact O-N 3.31Å; V18-K20 PolarHBondContact O-N 3.48Å
19G42.1Very low50.6Low55 Ų55128.7 Ų128.757%0.56768%0.678SS**THydrogen-bonded Turntrans-85.78178.800000116.7L15L15-G19 PolarHBondContact O-N 3.23Å
20K39.1Very low52.6Low186 Ų186124.2 Ų124.281%0.80965%0.649SS**THydrogen-bonded Turntrans-122.724.5-177.9-80.7-168177.6-175.20114.8V18V18-K20 PolarHBondContact O-N 3.48Å
21S38Very low54.8Low100 Ų100115.6 Ų115.670%0.69962%0.615SS**  trans-108.148.4159.7310000109.7L23S21-L23 VanDerWaalsContact C-N 3.29Å; S21-L23 PolarHBondContact O-N 3.13Å; S21-L23 VanDerWaalsContact O-N 3.13Å
22V40.7Very low56.9Low121 Ų121109.4 Ų109.473%0.73358%0.583SS**  trans-62.7109.2142.6177.30000103.3L24V22-L24 VanDerWaalsContact C-N 3.29Å; V22-L24 PolarHBondContact O-N 2.81Å
23L39.2Very low59.1Low150 Ų150103.3 Ų103.379%0.78555%0.551SS**  trans-45.9105.7164.3-139.988.3000104.8S21 Q25S21-L23 VanDerWaalsContact C-N 3.29Å; S21-L23 PolarHBondContact O-N 3.13Å; S21-L23 VanDerWaalsContact O-N 3.13Å; L23-Q25 PolarHBondContact O-N 2.82Å
24L38.5Very low61.4Low162 Ų16298.1 Ų98.185%0.84852%0.524SS*.  trans-61.589.9157.7-90158.8000102.4V22 E26V22-L24 VanDerWaalsContact C-N 3.29Å; V22-L24 PolarHBondContact O-N 2.81Å; L24-E26 PolarHBondContact O-N 2.75Å
25Q38Very low63.7Low161 Ų16191.9 Ų91.975%0.75249%0.493SS*.  trans-60.894.8157.6-168.7159.8-3.100101.9L23 N27L23-Q25 PolarHBondContact O-N 2.82Å; Q25-N27 PolarHBondContact O-N 2.99Å
26E45.5Very low66Low157 Ų15786 Ų8673%0.73446%0.462SS*.  trans-44.7120.7161-81.4-168.8152.600103.9L24 I28L24-E26 PolarHBondContact O-N 2.75Å; E26-I28 HydrophobicContact CB-CG1 4.27Å; E26-I28 WeakPolarHBondContact O-CG1 3.48Å; E26-I28 PolarHBondContact O-N 2.93Å
27N57.1Low68.3Low159 Ų15980.6 Ų80.685%0.8543%0.434SS*.  trans-65.485171.4-110.5-16.6000104.8Q25 K29Q25-N27 PolarHBondContact O-N 2.99Å; N27-K29 PolarHBondContact O-N 2.89Å
28I79Confident70.6Confident118 Ų11874.5 Ų74.561%0.60540%0.402SS*.  trans-65.1106.6-179.1-59.8178.6000104.6E26 N333E26-I28 HydrophobicContact CB-CG1 4.27Å; E26-I28 WeakPolarHBondContact O-CG1 3.48Å; E26-I28 PolarHBondContact O-N 2.93Å; I28-N333 WeakPolarHBondContact CG2-ND2 3.38Å; I28-N333 WeakPolarHBondContact CG2-OD1 3.42Å
29K92.8Very high73Confident72 Ų7269.5 Ų69.531%0.31337%0.371SS..PPolyproline II helixtrans-58.9128.3174.3-79.9176.7169.6-179.50108N27 Q128 Y130 P278 N333 S410N27-K29 PolarHBondContact O-N 2.89Å; K29-Q128 PolarHBondContact NZ-O 2.72Å; K29-Y130 HydrophobicContact CB-CE2 4.26Å; K29-Y130 WeakPolarHBondContact CB-OH 3.46Å; K29-Y130 HydrophobicContact CD-CE2 3.95Å; K29-Y130 HydrophobicContact CG-CE2 4.42Å; K29-P278 HydrophobicContact CB-CB 3.91Å; K29-P278 HydrophobicContact CB-CG 4.29Å; K29-N333 PolarHBondContact O-ND2 3.18Å; K29-N333 VanDerWaalsContact O-ND2 3.11Å; K29-S410 WeakPolarHBondContact CE-O 3.37Å
30P97.1Very high75.7Confident6 Ų666.9 Ų66.94%0.03934%0.344CS..PPolyproline II helixtrans-71.5155.4179.330.9-36.1000110.5F32 Y130 N333 W383 L409P30-F32 HydrophobicContact CG-CE1 3.97Å; P30-F32 HydrophobicContact CG-CZ 3.86Å; P30-Y130 WeakPolarHBondContact O-CE1 3.35Å; P30-Y130 VanDerWaalsContact O-CZ 3.3Å; P30-Y130 PolarHBondContact O-OH 3.11Å; P30-N333 CarbonylContact C-O 3.59Å; P30-N333 WeakPolarHBondContact CA-O 3.47Å; P30-W383 HydrophobicContact CB-CH2 3.54Å; P30-W383 HydrophobicContact CB-CZ2 3.41Å; P30-W383 VanDerWaalsContact CB-CZ2 3.41Å; P30-W383 HydrophobicContact CB-CZ3 4.43Å; P30-W383 HydrophobicContact CG-CH2 3.65Å; P30-W383 HydrophobicContact CG-CZ2 4.05Å; P30-W383 HydrophobicContact CG-CZ3 4.45Å; P30-L409 WeakPolarHBondContact CD-O 3.24Å; P30-L409 HydrophobicContact CG-CB 4.18Å
31N98.8Very high78.4Confident4 Ų458 Ų582%0.02131%0.306CS..EExtended strand (participates in β ladder)trans-81152.9164.5-54.9-47.9000110R277 P278 F279 N333 T334 L335N31-R277 PolarHBondContact OD1-O 3.32Å; N31-P278 WeakPolarHBondContact OD1-CA 3.19Å; N31-F279 CarbonylContact C-O 3.51Å; N31-F279 WeakPolarHBondContact CA-O 3.28Å; N31-F279 HydrophobicContact CB-CD1 4.11Å; N31-F279 HydrophobicContact CB-CD2 4.13Å; N31-F279 HydrophobicContact CB-CE1 3.79Å; N31-F279 HydrophobicContact CB-CE2 3.8Å; N31-F279 HydrophobicContact CB-CG 4.27Å; N31-F279 HydrophobicContact CB-CZ 3.62Å; N31-F279 WeakPolarHBondContact ND2-CE1 3.31Å; N31-F279 VanDerWaalsContact OD1-CD1 3.27Å; N31-F279 WeakPolarHBondContact OD1-CD1 3.16Å; N31-F279 WeakPolarHBondContact OD1-CE1 3.4Å; N31-F279 PolarHBondContact OD1-N 2.98Å; N31-N333 PolarHBondContact N-O 2.69Å; N31-T334 HydrophobicContact CB-CG2 3.89Å; N31-T334 PolarHBondContact ND2-OG1 2.77Å; N31-T334 WeakPolarHBondContact O-CA 3.36Å; N31-L335 PolarHBondContact O-N 3.3Å
32F98.9Very high81.3Confident0 Ų053.4 Ų53.40%027%0.273CS..EExtended strand (participates in β ladder)trans-120.1126.9174.7-55-67.3000109.7P30 V125 Y130 F279 L280 L281 L335 I406 L409P30-F32 HydrophobicContact CG-CE1 3.97Å; P30-F32 HydrophobicContact CG-CZ 3.86Å; F32-V125 HydrophobicContact CE2-CG1 4.28Å; F32-Y130 HydrophobicContact CD2-CD1 4.06Å; F32-Y130 AromaticContact CD2-CE1 3.46Å; F32-Y130 HydrophobicContact CD2-CE1 3.46Å; F32-Y130 VanDerWaalsContact CD2-CE1 3.46Å; F32-Y130 HydrophobicContact CE2-CD1 4.18Å; F32-Y130 AromaticContact CE2-CE1 3.3Å; F32-Y130 HydrophobicContact CE2-CE1 3.3Å; F32-Y130 HydrophobicContact CE2-CE2 4.42Å; F32-Y130 AromaticContact CE2-CZ 3.46Å; F32-Y130 VanDerWaalsContact CE2-CZ 3.46Å; F32-Y130 WeakPolarHBondContact CE2-OH 3.45Å; F32-Y130 HydrophobicContact CZ-CE1 4.39Å; F32-F279 PolarHBondContact N-O 3.5Å; F32-L280 HydrophobicContact CB-CB 4.31Å; F32-L280 HydrophobicContact CB-CD1 4.19Å; F32-L280 HydrophobicContact CB-CG 4.08Å; F32-L280 HydrophobicContact CD2-CB 4.39Å; F32-L280 HydrophobicContact CD2-CD1 4.18Å; F32-L280 CarbonylContact O-C 3.42Å; F32-L280 WeakPolarHBondContact O-CA 3.19Å; F32-L281 PolarHBondContact O-N 3.01Å; F32-L335 HydrophobicContact CD1-CB 4.1Å; F32-L335 HydrophobicContact CD1-CD2 4.1Å; F32-L335 HydrophobicContact CE1-CD2 4.25Å; F32-I406 HydrophobicContact CD1-CG1 4.17Å; F32-I406 HydrophobicContact CD2-CG2 4.09Å; F32-I406 HydrophobicContact CE1-CG1 4.33Å; F32-I406 HydrophobicContact CE2-CG2 3.89Å; F32-I406 HydrophobicContact CG-CG1 4.44Å; F32-I406 HydrophobicContact CG-CG2 4.47Å; F32-I406 HydrophobicContact CZ-CG2 4.13Å; F32-L409 HydrophobicContact CE1-CB 3.8Å; F32-L409 HydrophobicContact CE1-CD1 3.93Å; F32-L409 HydrophobicContact CZ-CB 3.7Å
33I98.9Very high84Confident0 Ų047.8 Ų47.80%024%0.24CC..EExtended strand (participates in β ladder)trans-124.3115.5166.2-60179.4000108.2M35 I271 F279 L281 I321 L325 T334 L335 L336 Y337I33-M35 HydrophobicContact CG2-CG 4.1Å; I33-I271 HydrophobicContact CD1-CD1 3.73Å; I33-I271 HydrophobicContact CD1-CG1 4.21Å; I33-F279 HydrophobicContact CD1-CE2 3.97Å; I33-F279 HydrophobicContact CD1-CZ 4.39Å; I33-F279 HydrophobicContact CG1-CE2 3.76Å; I33-L281 CarbonylContact C-O 3.39Å; I33-L281 WeakPolarHBondContact CA-O 3.07Å; I33-L281 HydrophobicContact CG1-CB 4.18Å; I33-L281 HydrophobicContact CG1-CD2 4.43Å; I33-L281 HydrophobicContact CG2-CD2 4.2Å; I33-I321 HydrophobicContact CD1-CG2 3.85Å; I33-I321 HydrophobicContact CG2-CG2 4.29Å; I33-L325 HydrophobicContact CD1-CD1 3.97Å; I33-L325 HydrophobicContact CD1-CD2 3.78Å; I33-L325 HydrophobicContact CD1-CG 4.26Å; I33-T334 HydrophobicContact CD1-CG2 4.04Å; I33-T334 HydrophobicContact CG1-CG2 3.98Å; I33-L335 PolarHBondContact N-O 3.27Å; I33-L336 HydrophobicContact CB-CD2 3.52Å; I33-L336 HydrophobicContact CD1-CD2 4.03Å; I33-L336 HydrophobicContact CG1-CD2 4.12Å; I33-L336 HydrophobicContact CG2-CD2 4.07Å; I33-L336 WeakPolarHBondContact O-CA 3.36Å; I33-Y337 PolarHBondContact O-N 3.38Å
34L98.9Very high86.7Confident0 Ų040.9 Ų40.90%020%0.204CC..EExtended strand (participates in β ladder)trans-110.3115.5-177-46.6174.3000107.3F85 F121 L280 L281 F282 L283 Y337 L402 I406L34-F85 HydrophobicContact CB-CZ 4.18Å; L34-F85 HydrophobicContact CD1-CE1 4.4Å; L34-F85 HydrophobicContact CD1-CZ 3.93Å; L34-F121 HydrophobicContact CD1-CD2 4.35Å; L34-F121 HydrophobicContact CD1-CE1 4.22Å; L34-F121 HydrophobicContact CD1-CE2 3.5Å; L34-F121 VanDerWaalsContact CD1-CE2 3.5Å; L34-F121 HydrophobicContact CD1-CZ 3.41Å; L34-F121 VanDerWaalsContact CD1-CZ 3.41Å; L34-L280 HydrophobicContact CD1-CD1 4.38Å; L34-L281 PolarHBondContact N-O 3.21Å; L34-F282 HydrophobicContact CB-CD2 4.01Å; L34-F282 CarbonylContact O-C 3.31Å; L34-L283 PolarHBondContact O-N 2.84Å; L34-Y337 HydrophobicContact CD2-CD1 4.31Å; L34-L402 HydrophobicContact CD2-CD1 4.01Å; L34-L402 HydrophobicContact CD2-CG 4.44Å; L34-I406 HydrophobicContact CD1-CD1 3.56Å; L34-I406 HydrophobicContact CD2-CD1 3.95Å; L34-I406 HydrophobicContact CG-CD1 4.35Å
35M98.9Very high89.6Confident1 Ų133.1 Ų33.11%0.00516%0.163CC..EExtended strand (participates in β ladder)trans-108.8117.6-179.8-67.5174.1-7200108.7I33 L61 L283 Y285 V318 L336 Y337 L338 T339I33-M35 HydrophobicContact CG2-CG 4.1Å; M35-L61 HydrophobicContact CE-CD2 3.95Å; M35-L283 WeakPolarHBondContact CA-O 3.24Å; M35-L283 HydrophobicContact CG-CB 4.31Å; M35-L283 HydrophobicContact CG-CD2 4.47Å; M35-Y285 HydrophobicContact CB-CE2 4.26Å; M35-Y285 HydrophobicContact CG-CE2 4.46Å; M35-V318 HydrophobicContact SD-CG1 4.34Å; M35-V318 HydrophobicContact SD-CG2 3.89Å; M35-L336 HydrophobicContact CE-CD1 4.14Å; M35-Y337 PolarHBondContact N-O 2.96Å; M35-L338 HydrophobicContact CB-CB 4.39Å; M35-L338 HydrophobicContact CB-CD1 4.43Å; M35-L338 HydrophobicContact CB-CG 4.31Å; M35-L338 HydrophobicContact CE-CB 4.35Å; M35-L338 HydrophobicContact CE-CD1 4.4Å; M35-L338 CarbonylContact O-C 3.51Å; M35-L338 VanDerWaalsContact O-CA 3.3Å; M35-L338 WeakPolarHBondContact O-CA 3.47Å; M35-T339 PolarHBondContact O-N 3.07Å
36M98.9Very high92.4Very high1 Ų126.5 Ų26.51%0.00514%0.138CC..EExtended strand (participates in β ladder)trans-122.7120.7178.6-179.2174.7-78.400109.2R82 F85 F282 L283 S284 Y285 T339 D341M36-R82 HydrophobicContact SD-CG 4.12Å; M36-F85 HydrophobicContact CE-CB 3.97Å; M36-F85 HydrophobicContact CE-CD1 3.57Å; M36-F85 HydrophobicContact CE-CD2 3.74Å; M36-F85 HydrophobicContact CE-CE1 3.93Å; M36-F85 HydrophobicContact CE-CE2 4.11Å; M36-F85 HydrophobicContact CE-CG 3.46Å; M36-F85 VanDerWaalsContact CE-CG 3.46Å; M36-F85 HydrophobicContact CE-CZ 4.18Å; M36-F282 HydrophobicContact CB-CE2 3.66Å; M36-F282 HydrophobicContact CB-CZ 4.23Å; M36-F282 HydrophobicContact CE-CZ 4.48Å; M36-F282 HydrophobicContact SD-CE2 4.28Å; M36-F282 HydrophobicContact SD-CZ 3.95Å; M36-L283 PolarHBondContact N-O 3.09Å; M36-S284 CarbonylContact O-C 3.53Å; M36-S284 WeakPolarHBondContact O-CA 3.31Å; M36-Y285 PolarHBondContact O-N 2.96Å; M36-T339 WeakPolarHBondContact CA-O 3.38Å; M36-T339 HydrophobicContact CB-CG2 4.37Å; M36-T339 HydrophobicContact CE-CG2 3.82Å; M36-T339 HydrophobicContact CG-CG2 4.26Å; M36-D341 HydrophobicContact CG-CB 4.14Å; M36-D341 HydrophobicContact SD-CB 3.72Å
37L98.4Very high94.9Very high1 Ų120.2 Ų20.21%0.00511%0.111CC..EExtended strand (participates in β ladder)trans-84.8163168.6-66.888.9000110.3L40 Y285 Q287 V314 L338 T339 S340 D341L37-L40 HydrophobicContact CB-CB 3.75Å; L37-L40 HydrophobicContact CB-CD2 4.41Å; L37-L40 HydrophobicContact CD1-CD2 4.26Å; L37-L40 HydrophobicContact CD2-CB 4.07Å; L37-L40 HydrophobicContact CD2-CD1 4.14Å; L37-L40 HydrophobicContact CD2-CD2 3.79Å; L37-L40 HydrophobicContact CD2-CG 4.19Å; L37-L40 HydrophobicContact CG-CB 4.49Å; L37-L40 HydrophobicContact CG-CD2 4.38Å; L37-Y285 HydrophobicContact CD1-CD2 4.45Å; L37-Y285 HydrophobicContact CG-CD2 4.16Å; L37-Q287 WeakPolarHBondContact CA-O 3.17Å; L37-V314 HydrophobicContact CD1-CG1 4.32Å; L37-V314 HydrophobicContact CD2-CB 4.16Å; L37-V314 HydrophobicContact CD2-CG1 3.6Å; L37-V314 HydrophobicContact CD2-CG2 4.26Å; L37-V314 HydrophobicContact CG-CG1 4Å; L37-L338 HydrophobicContact CD1-CD1 4.32Å; L37-L338 HydrophobicContact CD1-CD2 3.97Å; L37-L338 HydrophobicContact CD1-CG 4.06Å; L37-T339 WeakPolarHBondContact CD1-O 3.38Å; L37-T339 PolarHBondContact N-O 2.62Å; L37-S340 WeakPolarHBondContact O-CA 3.37Å; L37-D341 PolarHBondContact O-N 2.77Å
38D97.4Very high96.8Very high0 Ų014.5 Ų14.50%08%0.078CC..SBendtrans-112.5112.9-176.8-161.48.1000108.8L40 R82 K137 Q287 V288 H289 D341D38-L40 VanDerWaalsContact C-N 3.32Å; D38-L40 PolarHBondContact O-N 3.35Å; D38-R82 IonicContact OD1-NH2 2.73Å; D38-K137 IonicContact OD1-NZ 3.16Å; D38-K137 PolarHBondContact OD1-NZ 2.9Å; D38-K137 WeakPolarHBondContact OD2-CD 3.18Å; D38-K137 WeakPolarHBondContact OD2-CE 3.25Å; D38-K137 IonicContact OD2-NZ 3.55Å; D38-K137 PolarHBondContact OD2-NZ 3.46Å; D38-Q287 PolarHBondContact N-O 3.23Å; D38-Q287 CarbonylContact O-C 3.57Å; D38-V288 CarbonylContact O-C 3.49Å; D38-V288 VanDerWaalsContact O-C 3.31Å; D38-V288 WeakPolarHBondContact O-CA 3.28Å; D38-V288 PolarHBondContact O-N 2.92Å; D38-H289 HydrophobicContact CB-CB 3.8Å; D38-H289 PolarHBondContact O-N 3.48Å; D38-H289 IonicContact OD1-CD2 3.23Å; D38-H289 PolarHBondContact OD1-CD2 2.74Å; D38-H289 WeakPolarHBondContact OD2-CB 3.27Å; D38-H289 IonicContact OD2-CD2 2.74Å; D38-H289 IonicContact OD2-CG 3.72Å; D38-D341 WeakPolarHBondContact CA-OD1 3.4Å; D38-D341 VanDerWaalsContact OD1-OD2 3.06Å
39D96.7Very high97.6Very high5 Ų511.3 Ų11.33%0.0277%0.074CC..SBendtrans61.324.9-175.8-55.4-24.1000116.2G41 H289 D341 Q342 A344 K367D39-G41 PolarHBondContact O-N 2.68Å; D39-H289 IonicContact OD1-CD2 3.77Å; D39-H289 IonicContact OD2-CD2 3.36Å; D39-H289 PolarHBondContact OD2-CD2 3.29Å; D39-H289 IonicContact OD2-CG 3.04Å; D39-H289 IonicContact OD2-NE2 2.73Å; D39-D341 PolarHBondContact N-OD1 3.42Å; D39-Q342 PolarHBondContact OD1-NE2 3.26Å; D39-A344 VanDerWaalsContact O-CA 3.3Å; D39-A344 WeakPolarHBondContact O-CA 3.19Å; D39-K367 VanDerWaalsContact OD1-CD 3.3Å; D39-K367 WeakPolarHBondContact OD1-CD 3.4Å; D39-K367 VanDerWaalsContact OD1-CE 3.22Å; D39-K367 WeakPolarHBondContact OD1-CE 3.04Å; D39-K367 IonicContact OD1-NZ 2.61Å; D39-K367 PolarHBondContact OD1-NZ 3.01Å; D39-K367 IonicContact OD2-NZ 2.95Å; D39-K367 PolarHBondContact OD2-NZ 3Å
40L97.8Very high97.8Very high0 Ų08.6 Ų8.60%06%0.063CC..  trans-72.9124.6171.8-178.179.3000109.8L37 D38 D44 L45 V288 V311 S340 P378L37-L40 HydrophobicContact CB-CB 3.75Å; L37-L40 HydrophobicContact CB-CD2 4.41Å; L37-L40 HydrophobicContact CD1-CD2 4.26Å; L37-L40 HydrophobicContact CD2-CB 4.07Å; L37-L40 HydrophobicContact CD2-CD1 4.14Å; L37-L40 HydrophobicContact CD2-CD2 3.79Å; L37-L40 HydrophobicContact CD2-CG 4.19Å; L37-L40 HydrophobicContact CG-CB 4.49Å; L37-L40 HydrophobicContact CG-CD2 4.38Å; D38-L40 VanDerWaalsContact C-N 3.32Å; D38-L40 PolarHBondContact O-N 3.35Å; L40-D44 HydrophobicContact CD1-CB 3.67Å; L40-D44 HydrophobicContact CG-CB 4.32Å; L40-L45 HydrophobicContact CD2-CD1 4.08Å; L40-L45 HydrophobicContact CD2-CD2 3.77Å; L40-L45 HydrophobicContact CD2-CG 3.93Å; L40-V288 HydrophobicContact CB-CG2 4.19Å; L40-V288 HydrophobicContact CD1-CG2 4.16Å; L40-V311 HydrophobicContact CD1-CG2 4Å; L40-S340 PolarHBondContact N-OG 2.75Å; L40-S340 VanDerWaalsContact O-CB 3.3Å; L40-S340 WeakPolarHBondContact O-CB 3.41Å; L40-S340 PolarHBondContact O-OG 2.97Å; L40-P378 HydrophobicContact CD2-CG 4.05Å
41G97.3Very high97.6Very high0 Ų014.7 Ų14.70%010%0.1CC..  trans-75.5147175.600000112.3D39 G43 D44 W359 N360D39-G41 PolarHBondContact O-N 2.68Å; G41-G43 PolarHBondContact O-N 3.13Å; G41-D44 VanDerWaalsContact CA-OD2 3.28Å; G41-D44 WeakPolarHBondContact CA-OD2 2.96Å; G41-D44 PolarHBondContact N-OD2 3.21Å; G41-D44 WeakPolarHBondContact O-CB 3.44Å; G41-D44 PolarHBondContact O-N 2.93Å; G41-W359 CarbonylContact C-O 3.55Å; G41-W359 WeakPolarHBondContact CA-O 3.45Å; G41-N360 WeakPolarHBondContact CA-OD1 3.38Å
42I97.6Very high97.4Very high3 Ų317.9 Ų17.92%0.01512%0.12CC..THydrogen-bonded Turntrans-60.7-27.1177.5-175.5166.1000113.3D44 Y48 Y363 R376 P378I42-D44 VanDerWaalsContact C-N 3.32Å; I42-Y48 HydrophobicContact CD1-CD1 3.93Å; I42-Y48 HydrophobicContact CD1-CE1 3.86Å; I42-Y48 HydrophobicContact CG1-CD1 3.55Å; I42-Y48 HydrophobicContact CG1-CE1 3.88Å; I42-Y48 HydrophobicContact CG1-CG 4.18Å; I42-Y48 WeakPolarHBondContact O-CB 3.26Å; I42-Y363 HydrophobicContact CD1-CE2 3.92Å; I42-Y363 HydrophobicContact CG1-CE2 4.29Å; I42-Y363 HydrophobicContact CG2-CD2 3.32Å; I42-Y363 HydrophobicContact CG2-CE2 3.58Å; I42-Y363 HydrophobicContact CG2-CG 4.43Å; I42-R376 HydrophobicContact CD1-CG 3.68Å; I42-P378 HydrophobicContact CB-CG 4.47Å
43G97.3Very high97.1Very high3 Ų318 Ų183%0.03112%0.121CC..THydrogen-bonded Turntrans-81.3-6.9177.400000114.1G41 N50 W359G41-G43 PolarHBondContact O-N 3.13Å; G43-N50 WeakPolarHBondContact O-CB 3.37Å; G43-N50 PolarHBondContact O-ND2 2.97Å; G43-W359 CarbonylContact C-O 3.59Å; G43-W359 WeakPolarHBondContact CA-O 3.27Å; G43-W359 PolarHBondContact N-O 2.74Å; G43-W359 WeakPolarHBondContact O-CZ3 3.33Å
44D97.4Very high96.9Very high5 Ų527.2 Ų27.23%0.02716%0.155CC..SBendtrans-75.2-30.1-172.5-72.4-46.2000113.5L40 G41 I42 N50 L53 Y307 G358 W359L40-D44 HydrophobicContact CD1-CB 3.67Å; L40-D44 HydrophobicContact CG-CB 4.32Å; G41-D44 VanDerWaalsContact CA-OD2 3.28Å; G41-D44 WeakPolarHBondContact CA-OD2 2.96Å; G41-D44 PolarHBondContact N-OD2 3.21Å; G41-D44 WeakPolarHBondContact O-CB 3.44Å; G41-D44 PolarHBondContact O-N 2.93Å; I42-D44 VanDerWaalsContact C-N 3.32Å; D44-N50 VanDerWaalsContact O-CB 3.23Å; D44-N50 WeakPolarHBondContact O-CB 3.45Å; D44-N50 PolarHBondContact O-ND2 3.26Å; D44-L53 HydrophobicContact CB-CD2 4.15Å; D44-L53 WeakPolarHBondContact O-CD2 3.23Å; D44-Y307 VanDerWaalsContact CG-OH 3.32Å; D44-Y307 PolarHBondContact OD2-OH 3.43Å; D44-G358 WeakPolarHBondContact OD2-CA 3.46Å; D44-W359 PolarHBondContact N-O 3Å; D44-W359 WeakPolarHBondContact OD1-CB 3.28Å; D44-W359 PolarHBondContact OD1-N 3.2Å; D44-W359 PolarHBondContact OD2-N 3.47Å
45L98Very high96.8Very high0 Ų027.2 Ų27.20%016%0.155CC..SBendtrans-82.7146.2-174-57.9178.5000112.7L40 C47 Y48 G49 N50 T55 I58 L338 P378 I380L40-L45 HydrophobicContact CD2-CD1 4.08Å; L40-L45 HydrophobicContact CD2-CD2 3.77Å; L40-L45 HydrophobicContact CD2-CG 3.93Å; L45-C47 PolarHBondContact O-N 3.49Å; L45-Y48 HydrophobicContact CB-CD2 4.07Å; L45-Y48 HydrophobicContact CD1-CD2 4.01Å; L45-Y48 HydrophobicContact CD1-CE2 4.28Å; L45-Y48 CarbonylContact O-C 3.5Å; L45-Y48 PolarHBondContact O-N 3.37Å; L45-G49 PolarHBondContact O-N 3.38Å; L45-N50 WeakPolarHBondContact O-CB 3.28Å; L45-N50 PolarHBondContact O-N 3.17Å; L45-N50 VanDerWaalsContact O-N 3.14Å; L45-T55 HydrophobicContact CD2-CG2 3.85Å; L45-I58 HydrophobicContact CD1-CG2 3.87Å; L45-I58 HydrophobicContact CD2-CD1 3.91Å; L45-I58 HydrophobicContact CD2-CG2 4.14Å; L45-L338 HydrophobicContact CD1-CD2 4.35Å; L45-P378 HydrophobicContact CD1-CB 3.71Å; L45-P378 HydrophobicContact CD1-CG 3.77Å; L45-P378 HydrophobicContact CG-CG 4.43Å; L45-I380 HydrophobicContact CD1-CD1 4.25Å
46G97.8Very high96.8Very high21 Ų2130.9 Ų30.922%0.21618%0.179CC..G310 helixtrans-57.5-47.5176.400000112.8Y48 G49 N50 T55 D59G46-Y48 PolarHBondContact O-N 2.9Å; G46-Y48 VanDerWaalsContact O-N 3.09Å; G46-G49 PolarHBondContact O-N 3.11Å; G46-N50 WeakPolarHBondContact CA-O 3.28Å; G46-T55 PolarHBondContact N-OG1 3.28Å; G46-D59 WeakPolarHBondContact CA-OD1 3.32Å; G46-D59 PolarHBondContact N-OD1 3.33Å
47C97.7Very high96.8Very high25 Ų2532.5 Ų32.517%0.16919%0.188CC..G310 helixtrans-63.8-11.4176.555.30000115.1L45 D59 A62 K67L45-C47 PolarHBondContact O-N 3.49Å; C47-D59 HydrophobicContact CB-CB 4.39Å; C47-D59 WeakPolarHBondContact CB-OD1 3.22Å; C47-D59 PolarHBondContact N-OD1 2.99Å; C47-D59 PolarHBondContact SG-OD1 3.05Å; C47-D59 VanDerWaalsContact SG-OD1 3.34Å; C47-A62 HydrophobicContact CB-CB 3.82Å; C47-K67 VanDerWaalsContact O-CD 3.32Å; C47-K67 WeakPolarHBondContact O-CD 3.47Å; C47-K67 PolarHBondContact O-NZ 3.49Å; C47-K67 VanDerWaalsContact O-NZ 3.12Å
48Y98Very high96.8Very high40 Ų4032.5 Ų32.516%0.15719%0.188CC..G310 helixtrans-107.27.2172.7-77.6-91.8000113.6I42 L45 G46 K67 L68 P378 G379 I380I42-Y48 HydrophobicContact CD1-CD1 3.93Å; I42-Y48 HydrophobicContact CD1-CE1 3.86Å; I42-Y48 HydrophobicContact CG1-CD1 3.55Å; I42-Y48 HydrophobicContact CG1-CE1 3.88Å; I42-Y48 HydrophobicContact CG1-CG 4.18Å; I42-Y48 WeakPolarHBondContact O-CB 3.26Å; L45-Y48 HydrophobicContact CB-CD2 4.07Å; L45-Y48 HydrophobicContact CD1-CD2 4.01Å; L45-Y48 HydrophobicContact CD1-CE2 4.28Å; L45-Y48 CarbonylContact O-C 3.5Å; L45-Y48 PolarHBondContact O-N 3.37Å; G46-Y48 PolarHBondContact O-N 2.9Å; G46-Y48 VanDerWaalsContact O-N 3.09Å; Y48-K67 HydrophobicContact CD2-CD 4.36Å; Y48-K67 HydrophobicContact CE1-CD 4.27Å; Y48-K67 HydrophobicContact CE1-CG 4.12Å; Y48-K67 HydrophobicContact CE2-CD 4.06Å; Y48-K67 HydrophobicContact CE2-CG 3.88Å; Y48-K67 WeakPolarHBondContact OH-CG 3.42Å; Y48-L68 WeakPolarHBondContact CE1-O 3.48Å; Y48-L68 PolarHBondContact OH-O 3.36Å; Y48-P378 HydrophobicContact CD2-CB 4.44Å; Y48-P378 HydrophobicContact CE2-CB 3.87Å; Y48-G379 PolarHBondContact OH-N 2.74Å; Y48-G379 PolarHBondContact OH-O 2.93Å; Y48-I380 HydrophobicContact CE2-CD1 4.18Å; Y48-I380 HydrophobicContact CE2-CG1 4.07Å
49G95.8Very high96.9Very high51 Ų5134 Ų3453%0.52620%0.196SC..THydrogen-bonded Turntrans112.80.7169.200000115.6L45 G46 T51L45-G49 PolarHBondContact O-N 3.38Å; G46-G49 PolarHBondContact O-N 3.11Å; G49-T51 PolarHBondContact O-N 3.32Å
50N96.1Very high97Very high14 Ų1437.4 Ų37.48%0.07521%0.211CC..  trans-69.6127.6173.1-154.6-51.4000110.9G43 D44 L45 G46 T52 L53 W359G43-N50 WeakPolarHBondContact O-CB 3.37Å; G43-N50 PolarHBondContact O-ND2 2.97Å; D44-N50 VanDerWaalsContact O-CB 3.23Å; D44-N50 WeakPolarHBondContact O-CB 3.45Å; D44-N50 PolarHBondContact O-ND2 3.26Å; L45-N50 WeakPolarHBondContact O-CB 3.28Å; L45-N50 PolarHBondContact O-N 3.17Å; L45-N50 VanDerWaalsContact O-N 3.14Å; G46-N50 WeakPolarHBondContact CA-O 3.28Å; N50-T52 PolarHBondContact OD1-N 3.1Å; N50-T52 PolarHBondContact OD1-OG1 2.67Å; N50-L53 PolarHBondContact OD1-N 3.34Å; N50-W359 HydrophobicContact CB-CZ3 4.43Å
51T93.6Very high97Very high135 Ų13537.4 Ų37.483%0.82821%0.211SC*.SBendtrans-104.1-4.118054.80000113.4G49G49-T51 PolarHBondContact O-N 3.32Å
52T93.3Very high97Very high70 Ų7037.8 Ų37.843%0.42922%0.215SC..SBendtrans-117.6-35.8-171.254.30000112.6N50 H304N50-T52 PolarHBondContact OD1-N 3.1Å; N50-T52 PolarHBondContact OD1-OG1 2.67Å; T52-H304 PolarHBondContact OG1-NE2 2.89Å
53L94Very high97Very high3 Ų344.2 Ų44.22%0.01625%0.245CC..SBendtrans-88.7121.6171.8-166.161.1000109.1D44 N50 S302 Y307 G308 V311D44-L53 HydrophobicContact CB-CD2 4.15Å; D44-L53 WeakPolarHBondContact O-CD2 3.23Å; N50-L53 PolarHBondContact OD1-N 3.34Å; L53-S302 WeakPolarHBondContact CD1-OG 3.37Å; L53-Y307 HydrophobicContact CD2-CE1 4.47Å; L53-G308 VanDerWaalsContact CD1-CA 3.42Å; L53-V311 HydrophobicContact CD1-CB 4.27Å; L53-V311 HydrophobicContact CD1-CG1 4.45Å; L53-V311 HydrophobicContact CD2-CB 3.84Å; L53-V311 HydrophobicContact CD2-CG1 3.66Å; L53-V311 HydrophobicContact CD2-CG2 3.88Å; L53-V311 HydrophobicContact CG-CB 4.3Å; L53-V311 HydrophobicContact CG-CG1 4Å
54R93.6Very high97Very high194 Ų19446.6 Ų46.673%0.73226%0.255SS*.  trans-100119.4-171.2-60.9-173.5-168.7-178.74.2110.5P56 H312R54-P56 VanDerWaalsContact C-CD 3.4Å; R54-P56 WeakPolarHBondContact O-CD 3.32Å; R54-H312 PolarHBondContact N-NE2 3.26Å; R54-H312 PolarHBondContact O-CD2 3.01Å
55T98.2Very high97Very high0 Ų046.3 Ų46.30%025%0.254CS..  trans-126.258.5-179.852.50000111.4L45 G46 N57 I58 D59 V311 D315L45-T55 HydrophobicContact CD2-CG2 3.85Å; G46-T55 PolarHBondContact N-OG1 3.28Å; T55-N57 VanDerWaalsContact C-N 3.32Å; T55-N57 PolarHBondContact O-N 3.41Å; T55-I58 HydrophobicContact CG2-CD1 4.43Å; T55-I58 PolarHBondContact O-N 3.33Å; T55-D59 WeakPolarHBondContact O-CB 3.34Å; T55-D59 PolarHBondContact O-N 3.36Å; T55-D59 PolarHBondContact OG1-OD1 3.48Å; T55-V311 HydrophobicContact CG2-CG1 3.61Å; T55-D315 VanDerWaalsContact C-CG 3.5Å; T55-D315 WeakPolarHBondContact CA-OD1 3.36Å; T55-D315 HydrophobicContact CG2-CB 4.4Å; T55-D315 VanDerWaalsContact O-OD1 3.12Å
56P98.5Very high97Very high78 Ų7846.3 Ų46.351%0.50625%0.254SS..Hα-helixtrans-60.2-34.7-17024.9-36.2000114.4R54 Q60 D315R54-P56 VanDerWaalsContact C-CD 3.4Å; R54-P56 WeakPolarHBondContact O-CD 3.32Å; P56-Q60 WeakPolarHBondContact O-CB 3.06Å; P56-Q60 PolarHBondContact O-N 2.65Å; P56-D315 WeakPolarHBondContact CD-OD2 3.37Å; P56-D315 WeakPolarHBondContact CG-OD2 3.48Å
57N98.8Very high97.1Very high34 Ų3447.2 Ų47.218%0.18225%0.252CS..Hα-helixtrans-74.6-38.5-179.7-62.2-78.8000111.3T55 L61 D315 V318 G319T55-N57 VanDerWaalsContact C-N 3.32Å; T55-N57 PolarHBondContact O-N 3.41Å; N57-L61 PolarHBondContact O-N 3.12Å; N57-D315 WeakPolarHBondContact CB-O 3.41Å; N57-D315 PolarHBondContact N-OD1 3.44Å; N57-D315 PolarHBondContact N-OD2 3.04Å; N57-D315 PolarHBondContact ND2-O 2.55Å; N57-D315 PolarHBondContact ND2-OD2 3.02Å; N57-V318 HydrophobicContact CB-CB 4.46Å; N57-V318 HydrophobicContact CB-CG1 4.33Å; N57-G319 VanDerWaalsContact CG-CA 3.49Å; N57-G319 VanDerWaalsContact OD1-CA 3.28Å; N57-G319 WeakPolarHBondContact OD1-CA 3.18Å
58I98.8Very high97.1Very high1 Ų146.1 Ų46.11%0.00524%0.244CC..Hα-helixtrans-69.4-37.8174-61.5171.2000110.5L45 T55 Q60 L61 A62 D315 V318 L338 I380L45-I58 HydrophobicContact CD1-CG2 3.87Å; L45-I58 HydrophobicContact CD2-CD1 3.91Å; L45-I58 HydrophobicContact CD2-CG2 4.14Å; T55-I58 HydrophobicContact CG2-CD1 4.43Å; T55-I58 PolarHBondContact O-N 3.33Å; I58-Q60 VanDerWaalsContact C-N 3.35Å; I58-L61 WeakPolarHBondContact O-CB 3.28Å; I58-L61 PolarHBondContact O-N 2.61Å; I58-A62 PolarHBondContact O-N 3.05Å; I58-D315 HydrophobicContact CD1-CB 4.28Å; I58-D315 WeakPolarHBondContact CG1-OD1 3.5Å; I58-D315 PolarHBondContact N-OD1 2.85Å; I58-V318 HydrophobicContact CD1-CG2 4.4Å; I58-V318 HydrophobicContact CG1-CB 4.26Å; I58-V318 HydrophobicContact CG1-CG1 4.23Å; I58-V318 HydrophobicContact CG1-CG2 4.01Å; I58-L338 HydrophobicContact CD1-CD1 4.08Å; I58-L338 HydrophobicContact CG1-CD1 3.85Å; I58-L338 HydrophobicContact CG2-CD1 4.12Å; I58-L338 HydrophobicContact CG2-CD2 4.23Å; I58-I380 HydrophobicContact CG2-CD1 3.6Å
59D98.7Very high97.1Very high31 Ų3145.3 Ų45.317%0.16624%0.243CC..Hα-helixtrans-65.9-39.8176.9-64-13.8000111.1G46 C47 T55 L61 A62 Q63G46-D59 WeakPolarHBondContact CA-OD1 3.32Å; G46-D59 PolarHBondContact N-OD1 3.33Å; C47-D59 HydrophobicContact CB-CB 4.39Å; C47-D59 WeakPolarHBondContact CB-OD1 3.22Å; C47-D59 PolarHBondContact N-OD1 2.99Å; C47-D59 PolarHBondContact SG-OD1 3.05Å; C47-D59 VanDerWaalsContact SG-OD1 3.34Å; T55-D59 WeakPolarHBondContact O-CB 3.34Å; T55-D59 PolarHBondContact O-N 3.36Å; T55-D59 PolarHBondContact OG1-OD1 3.48Å; D59-L61 VanDerWaalsContact C-N 3.34Å; D59-A62 PolarHBondContact O-N 3.31Å; D59-Q63 VanDerWaalsContact O-CG 3.32Å; D59-Q63 WeakPolarHBondContact O-CG 3.37Å; D59-Q63 PolarHBondContact O-N 2.86Å
60Q98.3Very high97.2Very high77 Ų7743.4 Ų43.436%0.3622%0.221SC..Hα-helixtrans-59.2-45.4170.5178.7-178.91.100110.9P56 I58 A62 Q63 E64P56-Q60 WeakPolarHBondContact O-CB 3.06Å; P56-Q60 PolarHBondContact O-N 2.65Å; I58-Q60 VanDerWaalsContact C-N 3.35Å; Q60-A62 VanDerWaalsContact C-N 3.27Å; Q60-A62 PolarHBondContact O-N 3.32Å; Q60-Q63 PolarHBondContact O-N 3.24Å; Q60-Q63 VanDerWaalsContact O-N 3.12Å; Q60-E64 HydrophobicContact CG-CG 4.29Å; Q60-E64 VanDerWaalsContact CG-OE1 3.27Å; Q60-E64 WeakPolarHBondContact CG-OE1 3.24Å; Q60-E64 PolarHBondContact NE2-OE1 3.18Å; Q60-E64 WeakPolarHBondContact O-CB 3.39Å; Q60-E64 WeakPolarHBondContact O-CG 3.46Å; Q60-E64 PolarHBondContact O-N 3.09Å
61L97.8Very high97.4Very high0 Ų042.7 Ų42.70%022%0.217CC..Hα-helixtrans-57.7-40.8177.6-176.863.6000112.3M35 N57 I58 D59 G65 L322 L336 L338 I380 S382M35-L61 HydrophobicContact CE-CD2 3.95Å; N57-L61 PolarHBondContact O-N 3.12Å; I58-L61 WeakPolarHBondContact O-CB 3.28Å; I58-L61 PolarHBondContact O-N 2.61Å; D59-L61 VanDerWaalsContact C-N 3.34Å; L61-G65 PolarHBondContact O-N 3.44Å; L61-L322 HydrophobicContact CD1-CD2 4.33Å; L61-L336 HydrophobicContact CD1-CB 4.05Å; L61-L336 HydrophobicContact CD1-CD1 3.48Å; L61-L336 VanDerWaalsContact CD1-CD1 3.48Å; L61-L336 HydrophobicContact CD1-CG 4.32Å; L61-L336 HydrophobicContact CD2-CD1 4.46Å; L61-L338 HydrophobicContact CD2-CB 3.98Å; L61-L338 HydrophobicContact CD2-CD1 4.36Å; L61-I380 HydrophobicContact CB-CG2 4.39Å; L61-I380 HydrophobicContact CD2-CG2 4.13Å; L61-I380 HydrophobicContact CG-CG2 3.79Å; L61-S382 VanDerWaalsContact CD1-CB 3.43Å
62A98.2Very high97.6Very high8 Ų836.4 Ų36.47%0.06618%0.178CC..Hα-helixtrans-67.4-40.7175.400000112.5C47 I58 D59 Q60 E64 G65 I380C47-A62 HydrophobicContact CB-CB 3.82Å; I58-A62 PolarHBondContact O-N 3.05Å; D59-A62 PolarHBondContact O-N 3.31Å; Q60-A62 VanDerWaalsContact C-N 3.27Å; Q60-A62 PolarHBondContact O-N 3.32Å; A62-E64 VanDerWaalsContact C-N 3.32Å; A62-E64 PolarHBondContact O-N 3.34Å; A62-G65 CarbonylContact O-C 3.4Å; A62-G65 PolarHBondContact O-N 3.09Å; A62-I380 HydrophobicContact CB-CD1 4.11Å; A62-I380 HydrophobicContact CB-CG1 4.36Å; A62-I380 HydrophobicContact CB-CG2 4.03Å
63Q97.8Very high97.9Very high138 Ų13833 Ų3365%0.64516%0.158SC*.Hα-helixtrans-66-34.6176.9-71.4171.623.400112.4D59 Q60 G65 G390D59-Q63 VanDerWaalsContact O-CG 3.32Å; D59-Q63 WeakPolarHBondContact O-CG 3.37Å; D59-Q63 PolarHBondContact O-N 2.86Å; Q60-Q63 PolarHBondContact O-N 3.24Å; Q60-Q63 VanDerWaalsContact O-N 3.12Å; Q63-G65 VanDerWaalsContact C-N 3.29Å; Q63-G65 PolarHBondContact O-N 2.84Å; Q63-G390 WeakPolarHBondContact O-CA 3.36Å; Q63-G390 PolarHBondContact O-N 3.33Å
64E96.8Very high98Very high53 Ų5333.1 Ų33.125%0.24816%0.158CC..THydrogen-bonded Turntrans-79.9-8.2179.1-71.4177.4-175.500113.6Q60 A62 R331 S389Q60-E64 HydrophobicContact CG-CG 4.29Å; Q60-E64 VanDerWaalsContact CG-OE1 3.27Å; Q60-E64 WeakPolarHBondContact CG-OE1 3.24Å; Q60-E64 PolarHBondContact NE2-OE1 3.18Å; Q60-E64 WeakPolarHBondContact O-CB 3.39Å; Q60-E64 WeakPolarHBondContact O-CG 3.46Å; Q60-E64 PolarHBondContact O-N 3.09Å; A62-E64 VanDerWaalsContact C-N 3.32Å; A62-E64 PolarHBondContact O-N 3.34Å; E64-R331 IonicContact OE2-CZ 3.95Å; E64-R331 IonicContact OE2-NE 2.82Å; E64-R331 IonicContact OE2-NH2 3.75Å; E64-R331 PolarHBondContact OE2-NH2 3.15Å; E64-S389 WeakPolarHBondContact O-CB 3.32Å; E64-S389 PolarHBondContact O-OG 3.07Å
65G97.7Very high98.3Very high0 Ų024.1 Ų24.10%013%0.126CC..SBendtrans-141.5-144.1-173.600000114.2L61 A62 Q63 L381 P388 S389 G390 R391L61-G65 PolarHBondContact O-N 3.44Å; A62-G65 CarbonylContact O-C 3.4Å; A62-G65 PolarHBondContact O-N 3.09Å; Q63-G65 VanDerWaalsContact C-N 3.29Å; Q63-G65 PolarHBondContact O-N 2.84Å; G65-L381 CarbonylContact C-O 3.58Å; G65-L381 VanDerWaalsContact CA-O 3.3Å; G65-L381 WeakPolarHBondContact CA-O 3.22Å; G65-P388 CarbonylContact C-O 3.45Å; G65-S389 CarbonylContact O-C 3.55Å; G65-G390 PolarHBondContact O-N 2.76Å; G65-R391 PolarHBondContact O-N 3.23Å; G65-R391 VanDerWaalsContact O-N 3.13Å
66V98.5Very high98.2Very high0 Ų024.3 Ų24.30%013%0.127CC..EExtended strand (participates in β ladder)trans-107.3132.9176.9168.20000109.8L68 I380 L381 I387 R391 I393 L429V66-L68 HydrophobicContact CG1-CD2 3.75Å; V66-L68 HydrophobicContact CG1-CG 4.46Å; V66-I380 WeakPolarHBondContact O-CA 3.26Å; V66-L381 PolarHBondContact N-O 3.45Å; V66-L381 PolarHBondContact O-N 3.18Å; V66-I387 HydrophobicContact CB-CG2 4.18Å; V66-I387 HydrophobicContact CG2-CG2 3.38Å; V66-R391 CarbonylContact C-O 3.52Å; V66-R391 VanDerWaalsContact CA-O 3.29Å; V66-R391 WeakPolarHBondContact CA-O 3.43Å; V66-R391 HydrophobicContact CG2-CB 3.97Å; V66-R391 HydrophobicContact CG2-CG 4.39Å; V66-I393 HydrophobicContact CG1-CB 4.37Å; V66-I393 HydrophobicContact CG1-CD1 3.63Å; V66-I393 HydrophobicContact CG1-CG1 3.79Å; V66-I393 HydrophobicContact CG2-CD1 4.44Å; V66-L429 HydrophobicContact CB-CD2 4.04Å; V66-L429 HydrophobicContact CG1-CD2 3.84Å; V66-L429 HydrophobicContact CG2-CD2 4.28Å
67K98.6Very high98.2Very high40 Ų4021.7 Ų21.717%0.17411%0.109CC..EExtended strand (participates in β ladder)trans-103.7120168.3-173.3-175.468-177.70109.8C47 Y48 R391 E392 I393C47-K67 VanDerWaalsContact O-CD 3.32Å; C47-K67 WeakPolarHBondContact O-CD 3.47Å; C47-K67 PolarHBondContact O-NZ 3.49Å; C47-K67 VanDerWaalsContact O-NZ 3.12Å; Y48-K67 HydrophobicContact CD2-CD 4.36Å; Y48-K67 HydrophobicContact CE1-CD 4.27Å; Y48-K67 HydrophobicContact CE1-CG 4.12Å; Y48-K67 HydrophobicContact CE2-CD 4.06Å; Y48-K67 HydrophobicContact CE2-CG 3.88Å; Y48-K67 WeakPolarHBondContact OH-CG 3.42Å; K67-R391 PolarHBondContact N-O 3.44Å; K67-E392 WeakPolarHBondContact CE-OE2 3.35Å; K67-E392 IonicContact NZ-OE2 3.13Å; K67-E392 PolarHBondContact NZ-OE2 2.96Å; K67-E392 WeakPolarHBondContact O-CA 3.28Å; K67-I393 PolarHBondContact O-N 2.92Å
68L98.8Very high98.1Very high1 Ų120.2 Ų20.21%0.00510%0.101CC..EExtended strand (participates in β ladder)trans-88.5119.6175-54179.2000109.2Y48 V66 H71 G379 L381 I393 L429Y48-L68 WeakPolarHBondContact CE1-O 3.48Å; Y48-L68 PolarHBondContact OH-O 3.36Å; V66-L68 HydrophobicContact CG1-CD2 3.75Å; V66-L68 HydrophobicContact CG1-CG 4.46Å; L68-H71 HydrophobicContact CB-CB 3.83Å; L68-H71 HydrophobicContact CD1-CB 4.27Å; L68-H71 WeakPolarHBondContact CD1-ND1 3.48Å; L68-G379 VanDerWaalsContact CB-O 3.32Å; L68-G379 WeakPolarHBondContact CB-O 3.49Å; L68-G379 WeakPolarHBondContact CG-O 3.43Å; L68-G379 PolarHBondContact N-O 3.32Å; L68-L381 HydrophobicContact CD1-CD1 3.63Å; L68-L381 HydrophobicContact CG-CD1 4.12Å; L68-I393 CarbonylContact C-O 3.51Å; L68-I393 WeakPolarHBondContact CA-O 3.46Å; L68-I393 HydrophobicContact CD2-CB 3.87Å; L68-I393 HydrophobicContact CD2-CD1 4.36Å; L68-I393 HydrophobicContact CD2-CG2 4.26Å; L68-L429 HydrophobicContact CD2-CD2 4.38Å
69T98.1Very high98.1Very high24 Ų2420.1 Ų20.115%0.14710%0.101CC..SBendtrans-95.6-12.7-179550000113.6R376 E392 I393 D394T69-R376 PolarHBondContact O-NH1 3.2Å; T69-E392 VanDerWaalsContact CG2-CD 3.41Å; T69-E392 HydrophobicContact CG2-CG 3.49Å; T69-E392 VanDerWaalsContact CG2-CG 3.49Å; T69-E392 WeakPolarHBondContact CG2-OE1 3.33Å; T69-I393 PolarHBondContact N-O 3.45Å; T69-I393 PolarHBondContact OG1-O 2.99Å; T69-D394 WeakPolarHBondContact OG1-CA 3.36Å
70H98.4Very high98.1Very high10 Ų1018.9 Ų18.95%0.0469%0.094CC..SBendtrans-122.538177.5-155.1155.9000112.4R376 D394 T397 R453H70-R376 VanDerWaalsContact CD2-CZ 3.45Å; H70-R376 PolarHBondContact CD2-NH2 2.91Å; H70-R376 PolarHBondContact CE1-NH2 2.69Å; H70-R376 VanDerWaalsContact CE1-NH2 3.32Å; H70-R376 PolarHBondContact NE2-NH2 2.73Å; H70-D394 WeakPolarHBondContact CB-O 3.22Å; H70-D394 PolarHBondContact ND1-O 3.37Å; H70-T397 PolarHBondContact O-N 3.46Å; H70-T397 VanDerWaalsContact O-N 3.13Å; H70-R453 PolarHBondContact CD2-NH1 3.23Å; H70-R453 VanDerWaalsContact CD2-NH1 3.26Å; H70-R453 PolarHBondContact NE2-NE 3.23Å; H70-R453 PolarHBondContact NE2-NH1 2.6Å; H70-R453 VanDerWaalsContact NE2-NH1 3.14Å
71H98.8Very high98.1Very high0 Ų015.2 Ų15.20%08%0.077CC..EExtended strand (participates in β ladder)trans-82.7134.4176.7-157.653.6000111.5L68 Y337 R376 V377 T397 S398 N399L68-H71 HydrophobicContact CB-CB 3.83Å; L68-H71 HydrophobicContact CD1-CB 4.27Å; L68-H71 WeakPolarHBondContact CD1-ND1 3.48Å; H71-Y337 AromaticContact NE2-CE2 3.67Å; H71-Y337 AromaticContact NE2-CZ 3.63Å; H71-Y337 PolarHBondContact NE2-OH 3.27Å; H71-R376 WeakPolarHBondContact O-CA 3.42Å; H71-R376 WeakPolarHBondContact O-CG 3.39Å; H71-V377 PolarHBondContact O-N 2.69Å; H71-T397 CarbonylContact C-O 3.59Å; H71-T397 WeakPolarHBondContact CA-O 3.48Å; H71-T397 WeakPolarHBondContact CA-OG1 3.46Å; H71-T397 WeakPolarHBondContact ND1-CB 3.27Å; H71-T397 PolarHBondContact ND1-OG1 2.85Å; H71-S398 PolarHBondContact CE1-O 3.46Å; H71-S398 VanDerWaalsContact CE1-O 3.27Å; H71-N399 PolarHBondContact CD2-OD1 3.4Å; H71-N399 VanDerWaalsContact CD2-OD1 3.32Å; H71-N399 PolarHBondContact NE2-OD1 2.8Å
72V98.8Very high98.1Very high2 Ų215.3 Ų15.31%0.0128%0.077CC..EExtended strand (participates in β ladder)trans-127.5135.9-179.4-66.90000115.2I375 R376 T397 S398 N399 L441 R453V72-I375 CarbonylContact C-O 3.53Å; V72-I375 WeakPolarHBondContact CA-O 3.38Å; V72-I375 HydrophobicContact CG1-CD1 4.38Å; V72-I375 HydrophobicContact CG1-CG1 4.39Å; V72-R376 HydrophobicContact CG1-CB 4.46Å; V72-T397 VanDerWaalsContact CG2-O 3.24Å; V72-T397 WeakPolarHBondContact CG2-O 3.43Å; V72-T397 PolarHBondContact N-O 3.43Å; V72-S398 CarbonylContact O-C 3.44Å; V72-S398 WeakPolarHBondContact O-CA 3.34Å; V72-S398 PolarHBondContact O-OG 3.34Å; V72-N399 PolarHBondContact O-N 3.28Å; V72-L441 HydrophobicContact CG2-CD1 4Å; V72-R453 VanDerWaalsContact CG1-NH2 3.35Å
73A98.8Very high98.2Very high0 Ų014.9 Ų14.90%07%0.074CC..  trans-63.2145.516100000110.8A75 D341 I375 V377A73-A75 WeakPolarHBondContact CB-O 3.36Å; A73-A75 PolarHBondContact O-N 3.39Å; A73-D341 WeakPolarHBondContact CB-O 3.41Å; A73-I375 PolarHBondContact N-O 2.98Å; A73-V377 HydrophobicContact CB-CG1 4.19Å
74A97.3Very high98.2Very high4 Ų48.3 Ų8.33%0.0334%0.043CC..SBendtrans-73.9-15.8178.300000113.3A84 M400A74-A84 HydrophobicContact CB-CB 3.41Å; A74-A84 VanDerWaalsContact CB-CB 3.41Å; A74-M400 HydrophobicContact CB-CE 4.21Å; A74-M400 HydrophobicContact CB-CG 3.77Å; A74-M400 HydrophobicContact CB-SD 3.81Å
75A98.2Very high98.3Very high5 Ų55.9 Ų5.94%0.0413%0.032CC..SBendtrans-151.7156.3175.200000110A73 L77 P80 P91A73-A75 WeakPolarHBondContact CB-O 3.36Å; A73-A75 PolarHBondContact O-N 3.39Å; A75-L77 VanDerWaalsContact C-N 3.28Å; A75-L77 PolarHBondContact O-N 2.89Å; A75-P80 HydrophobicContact CB-CB 3.68Å; A75-P80 HydrophobicContact CB-CG 3.73Å; A75-P91 HydrophobicContact CB-CG 4.23Å
76S97.5Very high98.4Very high4 Ų45.9 Ų5.93%0.0283%0.032CC..SBendtrans-90.919179.959.30000114S368 T369S76-S368 PolarHBondContact O-N 2.93Å; S76-T369 WeakPolarHBondContact CB-O 3.44Å; S76-T369 PolarHBondContact OG-N 2.95Å; S76-T369 PolarHBondContact OG-O 3.41Å
77L97.3Very high98.4Very high24 Ų245.9 Ų5.913%0.1263%0.032CC..SBendtrans-139.1149179.5-71177.7000110.7A75 T79 P80 S81 V104 Q342 K367 N446A75-L77 VanDerWaalsContact C-N 3.28Å; A75-L77 PolarHBondContact O-N 2.89Å; L77-T79 PolarHBondContact O-N 3.4Å; L77-P80 HydrophobicContact CB-CG 3.8Å; L77-P80 WeakPolarHBondContact O-CD 3.41Å; L77-P80 WeakPolarHBondContact O-CG 3.39Å; L77-S81 VanDerWaalsContact O-CB 3.28Å; L77-S81 WeakPolarHBondContact O-CB 3.21Å; L77-S81 PolarHBondContact O-N 2.87Å; L77-V104 HydrophobicContact CB-CG1 3.93Å; L77-V104 HydrophobicContact CD1-CG1 4.42Å; L77-Q342 PolarHBondContact O-OE1 3.15Å; L77-K367 HydrophobicContact CD2-CG 4.33Å; L77-N446 WeakPolarHBondContact CD1-OD1 3.45Å
78C97.4Very high98.4Very high2 Ų24 Ų41%0.0142%0.024CC..Hα-helixtrans-55.4-61.3-169.7-41.60000113.4S81 R82 K137 H139 D341 Q342C78-S81 PolarHBondContact O-N 3.36Å; C78-R82 WeakPolarHBondContact O-CB 3.28Å; C78-R82 VanDerWaalsContact O-CD 3.31Å; C78-R82 WeakPolarHBondContact O-CD 3.23Å; C78-R82 VanDerWaalsContact O-CG 3.23Å; C78-R82 WeakPolarHBondContact O-CG 3.35Å; C78-R82 PolarHBondContact O-N 3.25Å; C78-K137 PolarHBondContact SG-NZ 3.06Å; C78-H139 VanDerWaalsContact CB-ND1 3.26Å; C78-H139 WeakPolarHBondContact CB-ND1 3.28Å; C78-D341 WeakPolarHBondContact CB-OD2 3.37Å; C78-Q342 VanDerWaalsContact CA-OE1 3.24Å; C78-Q342 VanDerWaalsContact N-OE1 3.14Å; C78-Q342 PolarHBondContact SG-NE2 2.9Å
79T98.5Very high98.4Very high0 Ų05 Ų50%03%0.027CC..Hα-helixtrans-54.9-55.3-174.8-63.20000112.5L77 S81 A83 V96 V104 F105 H139 L140L77-T79 PolarHBondContact O-N 3.4Å; T79-S81 PolarHBondContact O-N 2.99Å; T79-A83 PolarHBondContact O-N 3.19Å; T79-A83 VanDerWaalsContact O-N 3.09Å; T79-V96 HydrophobicContact CG2-CG1 3.46Å; T79-V96 VanDerWaalsContact CG2-CG1 3.46Å; T79-V104 WeakPolarHBondContact OG1-CB 3.44Å; T79-F105 HydrophobicContact CG2-CD2 3.49Å; T79-F105 VanDerWaalsContact CG2-CD2 3.49Å; T79-F105 HydrophobicContact CG2-CE2 3.48Å; T79-F105 VanDerWaalsContact CG2-CE2 3.48Å; T79-F105 HydrophobicContact CG2-CG 4.49Å; T79-F105 HydrophobicContact CG2-CZ 4.47Å; T79-F105 PolarHBondContact OG1-N 2.7Å; T79-H139 PolarHBondContact OG1-CD2 3.03Å; T79-H139 VanDerWaalsContact OG1-CD2 3.29Å; T79-H139 PolarHBondContact OG1-CE1 3.32Å; T79-H139 PolarHBondContact OG1-ND1 3.32Å; T79-H139 PolarHBondContact OG1-NE2 3.48Å; T79-H139 PolarHBondContact OG1-O 3.3Å; T79-L140 HydrophobicContact CG2-CD2 4.19Å; T79-L140 VanDerWaalsContact O-CD2 3.27Å; T79-L140 WeakPolarHBondContact O-CD2 3.28Å
80P98.4Very high98.4Very high4 Ų44.3 Ų4.33%0.0262%0.022CC..Hα-helixtrans-64.3-40.3178.222.1-31.6000112.9A75 L77 R82 A83 A84 P91 G103A75-P80 HydrophobicContact CB-CB 3.68Å; A75-P80 HydrophobicContact CB-CG 3.73Å; L77-P80 HydrophobicContact CB-CG 3.8Å; L77-P80 WeakPolarHBondContact O-CD 3.41Å; L77-P80 WeakPolarHBondContact O-CG 3.39Å; P80-R82 PolarHBondContact O-N 2.89Å; P80-A83 PolarHBondContact O-N 3.49Å; P80-A84 PolarHBondContact O-N 3.1Å; P80-P91 HydrophobicContact CB-CB 3.61Å; P80-P91 HydrophobicContact CB-CG 3.57Å; P80-P91 WeakPolarHBondContact O-CG 3.37Å; P80-G103 WeakPolarHBondContact CD-O 3.43Å
81S98.7Very high98.4Very high0 Ų03.9 Ų3.90%02%0.02CC..Hα-helixtrans-63.9-43.5-179-171.80000112.3L77 C78 T79 A83 A84 F85 D341L77-S81 VanDerWaalsContact O-CB 3.28Å; L77-S81 WeakPolarHBondContact O-CB 3.21Å; L77-S81 PolarHBondContact O-N 2.87Å; C78-S81 PolarHBondContact O-N 3.36Å; T79-S81 PolarHBondContact O-N 2.99Å; S81-A83 PolarHBondContact O-N 3.1Å; S81-A84 PolarHBondContact O-N 2.9Å; S81-F85 WeakPolarHBondContact O-CB 3.46Å; S81-F85 PolarHBondContact O-N 3.07Å; S81-D341 WeakPolarHBondContact CB-O 3.43Å; S81-D341 PolarHBondContact OG-O 2.86Å
82R98.8Very high98.3Very high2 Ų25.5 Ų5.51%0.0083%0.028CC..Hα-helixtrans-64.7-39.3176.4-69.9161.3179.8-80.2-9.2112.2M36 D38 C78 P80 A84 F85 L86 K137 L140 S284 D341M36-R82 HydrophobicContact SD-CG 4.12Å; D38-R82 IonicContact OD1-NH2 2.73Å; C78-R82 WeakPolarHBondContact O-CB 3.28Å; C78-R82 VanDerWaalsContact O-CD 3.31Å; C78-R82 WeakPolarHBondContact O-CD 3.23Å; C78-R82 VanDerWaalsContact O-CG 3.23Å; C78-R82 WeakPolarHBondContact O-CG 3.35Å; C78-R82 PolarHBondContact O-N 3.25Å; P80-R82 PolarHBondContact O-N 2.89Å; R82-A84 VanDerWaalsContact C-N 3.31Å; R82-A84 PolarHBondContact O-N 2.99Å; R82-F85 PolarHBondContact O-N 2.86Å; R82-L86 WeakPolarHBondContact O-CG 3.36Å; R82-L86 PolarHBondContact O-N 3.24Å; R82-L86 VanDerWaalsContact O-N 3.09Å; R82-K137 PolarHBondContact NH1-O 3.45Å; R82-L140 HydrophobicContact CB-CD1 4.37Å; R82-L140 HydrophobicContact CB-CD2 4.43Å; R82-L140 HydrophobicContact CB-CG 4.48Å; R82-S284 PolarHBondContact NH1-OG 3.08Å; R82-D341 HydrophobicContact CG-CB 4.23Å; R82-D341 IonicContact CZ-OD2 3.89Å; R82-D341 IonicContact NE-OD2 2.75Å; R82-D341 PolarHBondContact NE-OD2 3.46Å; R82-D341 IonicContact NH2-OD2 3.44Å; R82-D341 PolarHBondContact NH2-OD2 2.83Å
83A98.8Very high98.3Very high0 Ų06 Ų60%03%0.03CC..Hα-helixtrans-60-44.9173.800000111T79 P80 S81 L86 T87 V96 L114 L140T79-A83 PolarHBondContact O-N 3.19Å; T79-A83 VanDerWaalsContact O-N 3.09Å; P80-A83 PolarHBondContact O-N 3.49Å; S81-A83 PolarHBondContact O-N 3.1Å; A83-L86 PolarHBondContact O-N 2.95Å; A83-T87 WeakPolarHBondContact O-CB 3.25Å; A83-T87 WeakPolarHBondContact O-CG2 3.24Å; A83-T87 PolarHBondContact O-N 2.97Å; A83-T87 PolarHBondContact O-OG1 2.61Å; A83-V96 HydrophobicContact CB-CB 3.87Å; A83-V96 HydrophobicContact CB-CG1 3.9Å; A83-V96 HydrophobicContact CB-CG2 3.97Å; A83-L114 HydrophobicContact CB-CD1 4.38Å; A83-L140 HydrophobicContact CB-CD2 3.72Å
84A98.8Very high98.2Very high0 Ų06 Ų60%03%0.03CC..Hα-helixtrans-68.2-41.3179.700000112.8A74 P80 S81 R82 L86 T87 G88 R89 P91 M400A74-A84 HydrophobicContact CB-CB 3.41Å; A74-A84 VanDerWaalsContact CB-CB 3.41Å; P80-A84 PolarHBondContact O-N 3.1Å; S81-A84 PolarHBondContact O-N 2.9Å; R82-A84 VanDerWaalsContact C-N 3.31Å; R82-A84 PolarHBondContact O-N 2.99Å; A84-L86 VanDerWaalsContact C-N 3.34Å; A84-L86 PolarHBondContact O-N 3.37Å; A84-T87 PolarHBondContact O-N 2.82Å; A84-G88 WeakPolarHBondContact O-CA 3.39Å; A84-G88 PolarHBondContact O-N 3.35Å; A84-R89 WeakPolarHBondContact CA-O 3.32Å; A84-R89 WeakPolarHBondContact CB-O 3.41Å; A84-P91 HydrophobicContact CB-CG 4.19Å; A84-M400 HydrophobicContact CB-CG 3.99Å; A84-M400 HydrophobicContact CB-SD 4.3Å
85F98.9Very high98.2Very high1 Ų16 Ų60%0.0043%0.03CC..Hα-helixtrans-56.1-47.4174.3173.6-110.9000112L34 M36 S81 R82 T87 F121 F282 Y337 N399 L402L34-F85 HydrophobicContact CB-CZ 4.18Å; L34-F85 HydrophobicContact CD1-CE1 4.4Å; L34-F85 HydrophobicContact CD1-CZ 3.93Å; M36-F85 HydrophobicContact CE-CB 3.97Å; M36-F85 HydrophobicContact CE-CD1 3.57Å; M36-F85 HydrophobicContact CE-CD2 3.74Å; M36-F85 HydrophobicContact CE-CE1 3.93Å; M36-F85 HydrophobicContact CE-CE2 4.11Å; M36-F85 HydrophobicContact CE-CG 3.46Å; M36-F85 VanDerWaalsContact CE-CG 3.46Å; M36-F85 HydrophobicContact CE-CZ 4.18Å; S81-F85 WeakPolarHBondContact O-CB 3.46Å; S81-F85 PolarHBondContact O-N 3.07Å; R82-F85 PolarHBondContact O-N 2.86Å; F85-T87 PolarHBondContact O-N 2.81Å; F85-F121 AromaticContact CD1-CE1 3.98Å; F85-F121 HydrophobicContact CD1-CE1 3.98Å; F85-F121 HydrophobicContact CD1-CZ 4.23Å; F85-F121 AromaticContact CE1-CE1 3.69Å; F85-F121 HydrophobicContact CE1-CE1 3.69Å; F85-F121 AromaticContact CE1-CZ 3.6Å; F85-F121 HydrophobicContact CE1-CZ 3.6Å; F85-F121 HydrophobicContact CE2-CE1 4.47Å; F85-F121 AromaticContact CZ-CE1 3.96Å; F85-F121 HydrophobicContact CZ-CE1 3.96Å; F85-F121 HydrophobicContact CZ-CZ 4.01Å; F85-F121 WeakPolarHBondContact O-CE1 3.34Å; F85-F282 HydrophobicContact CD1-CE1 4.27Å; F85-F282 HydrophobicContact CD1-CE2 4.32Å; F85-F282 AromaticContact CD1-CZ 3.89Å; F85-F282 HydrophobicContact CD1-CZ 3.89Å; F85-F282 HydrophobicContact CE1-CD1 4.45Å; F85-F282 HydrophobicContact CE1-CD2 4.09Å; F85-F282 HydrophobicContact CE1-CE1 4.05Å; F85-F282 AromaticContact CE1-CE2 3.61Å; F85-F282 HydrophobicContact CE1-CE2 3.61Å; F85-F282 AromaticContact CE1-CZ 3.61Å; F85-F282 HydrophobicContact CE1-CZ 3.61Å; F85-F282 HydrophobicContact CZ-CE2 4.37Å; F85-Y337 HydrophobicContact CD2-CE1 4.45Å; F85-Y337 HydrophobicContact CE2-CD1 4.14Å; F85-Y337 AromaticContact CE2-CE1 3.56Å; F85-Y337 HydrophobicContact CE2-CE1 3.56Å; F85-Y337 HydrophobicContact CZ-CD1 4.37Å; F85-Y337 HydrophobicContact CZ-CE1 4.15Å; F85-N399 HydrophobicContact CD2-CB 4.28Å; F85-N399 WeakPolarHBondContact CD2-O 3.37Å; F85-L402 HydrophobicContact CD2-CB 4.35Å; F85-L402 HydrophobicContact CE2-CB 3.74Å; F85-L402 HydrophobicContact CE2-CG 4.06Å
86L98.9Very high98.1Very high1 Ų15.8 Ų5.81%0.0053%0.028CC..Hα-helixtrans-71-29.4-177.7-68.5172.8000113.7R82 A83 A84 T120 F121 W138 L140 F159 F282 F403R82-L86 WeakPolarHBondContact O-CG 3.36Å; R82-L86 PolarHBondContact O-N 3.24Å; R82-L86 VanDerWaalsContact O-N 3.09Å; A83-L86 PolarHBondContact O-N 2.95Å; A84-L86 VanDerWaalsContact C-N 3.34Å; A84-L86 PolarHBondContact O-N 3.37Å; L86-T120 HydrophobicContact CB-CG2 3.94Å; L86-T120 CarbonylContact O-C 3.47Å; L86-T120 WeakPolarHBondContact O-CA 3.49Å; L86-F121 HydrophobicContact CD2-CE1 3.75Å; L86-F121 HydrophobicContact CD2-CE2 4.22Å; L86-F121 HydrophobicContact CD2-CZ 3.51Å; L86-F121 WeakPolarHBondContact O-CD1 3.47Å; L86-F121 PolarHBondContact O-N 2.97Å; L86-W138 HydrophobicContact CD1-CE3 4.26Å; L86-W138 HydrophobicContact CD1-CH2 3.48Å; L86-W138 VanDerWaalsContact CD1-CH2 3.48Å; L86-W138 HydrophobicContact CD1-CZ3 3.23Å; L86-L140 HydrophobicContact CD1-CD1 3.39Å; L86-F159 HydrophobicContact CD2-CE2 4.38Å; L86-F159 HydrophobicContact CD2-CZ 4.16Å; L86-F282 HydrophobicContact CD2-CD1 4.06Å; L86-F282 HydrophobicContact CD2-CE1 3.97Å; L86-F403 VanDerWaalsContact O-CD2 3.25Å; L86-F403 WeakPolarHBondContact O-CD2 3.44Å
87T98.9Very high97.9Very high0 Ų05.8 Ų5.80%03%0.029CC..Hα-helixtrans-108.9-11.4-169.8600000114.3A83 A84 F85 R89 L114 E118 F403A83-T87 WeakPolarHBondContact O-CB 3.25Å; A83-T87 WeakPolarHBondContact O-CG2 3.24Å; A83-T87 PolarHBondContact O-N 2.97Å; A83-T87 PolarHBondContact O-OG1 2.61Å; A84-T87 PolarHBondContact O-N 2.82Å; F85-T87 PolarHBondContact O-N 2.81Å; T87-R89 PolarHBondContact O-N 2.75Å; T87-R89 PolarHBondContact OG1-N 2.96Å; T87-L114 HydrophobicContact CG2-CD1 4.15Å; T87-L114 HydrophobicContact CG2-CD2 4.29Å; T87-E118 HydrophobicContact CG2-CB 4.1Å; T87-F403 VanDerWaalsContact C-CD2 3.45Å
88G98.8Very high97.5Very high0 Ų04.7 Ų4.70%02%0.023CC..THydrogen-bonded Turntrans63.722-173.200000113.7A84 M400 F403 D421 G422A84-G88 WeakPolarHBondContact O-CA 3.39Å; A84-G88 PolarHBondContact O-N 3.35Å; G88-M400 WeakPolarHBondContact CA-O 3.24Å; G88-F403 VanDerWaalsContact CA-CB 3.49Å; G88-D421 PolarHBondContact O-N 3.47Å; G88-G422 PolarHBondContact O-N 3.07Å
89R98.7Very high97.1Very high23 Ų239.2 Ų9.29%0.0875%0.048CC..SBendtrans-130.3144.6-170.6-74.3161.359.482.4-4.9111.2A84 T87 R93 E118 M400 E419 I420 D421A84-R89 WeakPolarHBondContact CA-O 3.32Å; A84-R89 WeakPolarHBondContact CB-O 3.41Å; T87-R89 PolarHBondContact O-N 2.75Å; T87-R89 PolarHBondContact OG1-N 2.96Å; R89-R93 HydrophobicContact CB-CB 4.5Å; R89-R93 PolarHBondContact NH2-O 2.91Å; R89-E118 IonicContact CZ-OE2 3.18Å; R89-E118 IonicContact NE-OE2 2.74Å; R89-E118 PolarHBondContact NE-OE2 2.83Å; R89-M400 VanDerWaalsContact C-SD 3.59Å; R89-E419 VanDerWaalsContact CG-O 3.25Å; R89-E419 WeakPolarHBondContact CG-O 3.48Å; R89-E419 PolarHBondContact NH1-O 3.4Å; R89-I420 HydrophobicContact CG-CD1 3.98Å; R89-D421 VanDerWaalsContact CA-OD2 3.28Å; R89-D421 WeakPolarHBondContact CA-OD2 3.08Å
90Y98.7Very high96.5Very high8 Ų812.5 Ų12.53%0.0316%0.064CC..  trans-57.5143172.9-74.9-68.5000111.3I92 R93 M400 D421 F442 Y444 H536Y90-I92 PolarHBondContact O-N 3.21Å; Y90-I92 VanDerWaalsContact O-N 3.08Å; Y90-R93 WeakPolarHBondContact O-CB 3.43Å; Y90-R93 PolarHBondContact O-N 3.12Å; Y90-M400 HydrophobicContact CD1-CE 3.95Å; Y90-M400 HydrophobicContact CD1-SD 4.06Å; Y90-M400 HydrophobicContact CE1-CE 3.47Å; Y90-M400 VanDerWaalsContact CE1-CE 3.47Å; Y90-M400 HydrophobicContact CE1-SD 4.22Å; Y90-M400 HydrophobicContact CE2-CE 4.1Å; Y90-M400 HydrophobicContact CG-CE 4.43Å; Y90-M400 HydrophobicContact CG-SD 4.27Å; Y90-D421 HydrophobicContact CD2-CB 3.78Å; Y90-D421 VanDerWaalsContact CD2-OD1 3.28Å; Y90-D421 WeakPolarHBondContact CD2-OD1 3.29Å; Y90-D421 WeakPolarHBondContact CD2-OD2 3.35Å; Y90-D421 HydrophobicContact CE2-CB 3.73Å; Y90-D421 PolarHBondContact N-OD2 2.9Å; Y90-F442 HydrophobicContact CE1-CB 4.33Å; Y90-F442 WeakPolarHBondContact CE1-O 3.43Å; Y90-F442 HydrophobicContact CE2-CB 4.37Å; Y90-F442 HydrophobicContact CE2-CD2 4.01Å; Y90-F442 PolarHBondContact OH-N 3.31Å; Y90-Y444 HydrophobicContact CD1-CD2 4.32Å; Y90-H536 AromaticContact CD2-CE1 3.66Å; Y90-H536 AromaticContact CE2-CE1 3.83Å
91P98Very high95.9Very high2 Ų217.2 Ų17.21%0.0138%0.082CC..Hα-helixtrans-57.9-29.7-176.6-23.131.7000114.1A75 P80 A84 R93 S94 G95 V96 A97A75-P91 HydrophobicContact CB-CG 4.23Å; P80-P91 HydrophobicContact CB-CB 3.61Å; P80-P91 HydrophobicContact CB-CG 3.57Å; P80-P91 WeakPolarHBondContact O-CG 3.37Å; A84-P91 HydrophobicContact CB-CG 4.19Å; P91-R93 PolarHBondContact O-N 3.21Å; P91-S94 PolarHBondContact O-N 2.85Å; P91-S94 PolarHBondContact O-OG 2.85Å; P91-S94 VanDerWaalsContact O-OG 3.12Å; P91-G95 PolarHBondContact O-N 2.75Å; P91-V96 WeakPolarHBondContact CB-O 3.36Å; P91-V96 PolarHBondContact O-N 3.39Å; P91-V96 VanDerWaalsContact O-N 3.15Å; P91-A97 HydrophobicContact CB-CB 4.28Å
92I97.4Very high95.1Very high33 Ų3319.5 Ų19.517%0.16910%0.097CC..Hα-helixtrans-62.6-26.2175.6-165.160.4000112.8Y90 A97 Y444 V540 V543Y90-I92 PolarHBondContact O-N 3.21Å; Y90-I92 VanDerWaalsContact O-N 3.08Å; I92-A97 HydrophobicContact CD1-CB 4.15Å; I92-Y444 HydrophobicContact CB-CE1 4.28Å; I92-Y444 HydrophobicContact CG1-CE1 4.34Å; I92-Y444 HydrophobicContact CG2-CE1 4.18Å; I92-Y444 HydrophobicContact CG2-CE2 4.17Å; I92-V540 HydrophobicContact CB-CG1 4.45Å; I92-V540 HydrophobicContact CG1-CG1 3.82Å; I92-V540 HydrophobicContact CG2-CG1 3.86Å; I92-V540 HydrophobicContact CG2-CG2 4.14Å; I92-V543 VanDerWaalsContact O-CG2 3.23Å; I92-V543 WeakPolarHBondContact O-CG2 3.48Å
93R98.1Very high94.6Very high14 Ų1419.6 Ų19.65%0.05310%0.098CC..Hα-helixtrans-81.6-26.6179.8-56.4-172.8-174.3-79.56.1113.3R89 Y90 P91 D421 S539R89-R93 HydrophobicContact CB-CB 4.5Å; R89-R93 PolarHBondContact NH2-O 2.91Å; Y90-R93 WeakPolarHBondContact O-CB 3.43Å; Y90-R93 PolarHBondContact O-N 3.12Å; P91-R93 PolarHBondContact O-N 3.21Å; R93-D421 WeakPolarHBondContact CD-OD2 3.2Å; R93-D421 IonicContact CZ-OD1 3.65Å; R93-D421 VanDerWaalsContact CZ-OD1 3.27Å; R93-D421 IonicContact CZ-OD2 2.74Å; R93-D421 VanDerWaalsContact NE-CG 3.29Å; R93-D421 IonicContact NE-OD1 3.2Å; R93-D421 PolarHBondContact NE-OD1 2.93Å; R93-D421 IonicContact NE-OD2 2.85Å; R93-D421 PolarHBondContact NE-OD2 3.03Å; R93-D421 IonicContact NH2-OD1 4Å; R93-D421 PolarHBondContact NH2-OD1 2.91Å; R93-S539 PolarHBondContact NH1-O 3.48Å; R93-S539 VanDerWaalsContact NH1-O 3.11Å; R93-S539 PolarHBondContact NH1-OG 3.24Å; R93-S539 PolarHBondContact NH2-OG 2.97Å
94S97Very high94.5Very high0 Ų021 Ų210%011%0.107CC..Hα-helixtrans-93.8-9.2178.658.40000113P91 V96P91-S94 PolarHBondContact O-N 2.85Å; P91-S94 PolarHBondContact O-OG 2.85Å; P91-S94 VanDerWaalsContact O-OG 3.12Å; S94-V96 VanDerWaalsContact C-N 3.27Å
95G95.9Very high94.4Very high3 Ų321.1 Ų21.13%0.03111%0.107CC..THydrogen-bonded Turntrans841.6-176.700000113.2P91 A97 E544 Q546P91-G95 PolarHBondContact O-N 2.75Å; G95-A97 PolarHBondContact O-N 3.31Å; G95-E544 WeakPolarHBondContact CA-O 3.35Å; G95-Q546 WeakPolarHBondContact O-CB 3.44Å; G95-Q546 PolarHBondContact O-N 3.05Å
96V97Very high94.1Very high0 Ų023.2 Ų23.20%012%0.118CC..  trans-84.948.2177.4-1670000110T79 A83 P91 S94 L114 L140T79-V96 HydrophobicContact CG2-CG1 3.46Å; T79-V96 VanDerWaalsContact CG2-CG1 3.46Å; A83-V96 HydrophobicContact CB-CB 3.87Å; A83-V96 HydrophobicContact CB-CG1 3.9Å; A83-V96 HydrophobicContact CB-CG2 3.97Å; P91-V96 WeakPolarHBondContact CB-O 3.36Å; P91-V96 PolarHBondContact O-N 3.39Å; P91-V96 VanDerWaalsContact O-N 3.15Å; S94-V96 VanDerWaalsContact C-N 3.27Å; V96-L114 HydrophobicContact CG2-CD1 4.1Å; V96-L140 HydrophobicContact CG1-CD2 4.36Å
97A93.3Very high94Very high5 Ų524.2 Ų24.24%0.04112%0.122CC..  trans-148.9140.1176.400000108.3P91 I92 G95 S545P91-A97 HydrophobicContact CB-CB 4.28Å; I92-A97 HydrophobicContact CD1-CB 4.15Å; G95-A97 PolarHBondContact O-N 3.31Å; A97-S545 PolarHBondContact O-OG 2.94Å
98G89Confident93.9Very high1 Ų124.5 Ų24.51%0.0112%0.124CC..  trans-145.6155-17600000114.1L100 N446 S447G98-L100 VanDerWaalsContact C-N 3.26Å; G98-L100 PolarHBondContact O-N 3.45Å; G98-N446 WeakPolarHBondContact O-CB 3.25Å; G98-S447 PolarHBondContact O-OG 3.36Å; G98-S447 VanDerWaalsContact O-OG 3.13Å
99N88.4Confident93.8Very high97 Ų9724.5 Ų24.552%0.51912%0.124SC..SBendtrans-841.2-178.1-68.7-34.4000113.4S447 Y448N99-S447 PolarHBondContact N-OG 3.45Å; N99-S447 WeakPolarHBondContact OD1-CB 3.48Å; N99-S447 PolarHBondContact OD1-OG 2.93Å; N99-Y448 HydrophobicContact CB-CE2 4.35Å; N99-Y448 WeakPolarHBondContact CB-OH 3.23Å; N99-Y448 PolarHBondContact O-OH 2.97Å
100L86.1Confident93.7Very high68 Ų6823.5 Ų23.536%0.35612%0.12SC..SBendtrans-87.6164.1-178.1-60.7179.8000111.2G98 A549 I552G98-L100 VanDerWaalsContact C-N 3.26Å; G98-L100 PolarHBondContact O-N 3.45Å; L100-A549 HydrophobicContact CD1-CB 3.87Å; L100-A549 VanDerWaalsContact CD1-N 3.28Å; L100-I552 HydrophobicContact CD1-CD1 3.81Å
101R85Confident93.7Very high104 Ų10423.6 Ų23.639%0.39212%0.122SC..SBendtrans-59.7-43.6176.3-65.8-178.1-173.8171.6-0.1112.5G103 F487 T489R101-G103 PolarHBondContact O-N 3.25Å; R101-G103 VanDerWaalsContact O-N 3.16Å; R101-F487 HydrophobicContact CB-CD1 4.02Å; R101-F487 HydrophobicContact CB-CE1 3.82Å; R101-F487 HydrophobicContact CB-CZ 4.13Å; R101-F487 HydrophobicContact CG-CD1 4.35Å; R101-F487 HydrophobicContact CG-CD2 4.4Å; R101-F487 HydrophobicContact CG-CE1 4.44Å; R101-F487 HydrophobicContact CG-CE2 4.47Å; R101-F487 HydrophobicContact CG-CG 4.35Å; R101-T489 HydrophobicContact CG-CG2 4.31Å
102P82.1Confident93.7Very high48 Ų4823.5 Ų23.531%0.31212%0.122SC..  trans-70110.9171-16.532.8000110.1V104 I552P102-V104 VanDerWaalsContact C-N 3.34Å; P102-I552 HydrophobicContact CB-CD1 4.14Å; P102-I552 HydrophobicContact CG-CD1 4.01Å
103G89.5Confident93.7Very high4 Ų421.9 Ų21.94%0.04111%0.114CC..  trans-91.56.4172.700000114.1P80 R101 N446 L547P80-G103 WeakPolarHBondContact CD-O 3.43Å; R101-G103 PolarHBondContact O-N 3.25Å; R101-G103 VanDerWaalsContact O-N 3.16Å; G103-N446 WeakPolarHBondContact CA-OD1 3.35Å; G103-L547 WeakPolarHBondContact O-CD1 3.4Å
104V95.6Very high93.7Very high29 Ų2921.2 Ų21.218%0.17611%0.111CC..SBendtrans-142.2160.5-177-610000110.7L77 T79 P102 I106L77-V104 HydrophobicContact CB-CG1 3.93Å; L77-V104 HydrophobicContact CD1-CG1 4.42Å; T79-V104 WeakPolarHBondContact OG1-CB 3.44Å; P102-V104 VanDerWaalsContact C-N 3.34Å; V104-I106 HydrophobicContact CG2-CG2 4.16Å
105F96.4Very high93.7Very high2 Ų222.5 Ų22.51%0.00912%0.118CC..  trans-73.1137.9171.4-62.4-62.9000110.5T79 G112 H139 L167 Q546 L547 I552T79-F105 HydrophobicContact CG2-CD2 3.49Å; T79-F105 VanDerWaalsContact CG2-CD2 3.49Å; T79-F105 HydrophobicContact CG2-CE2 3.48Å; T79-F105 VanDerWaalsContact CG2-CE2 3.48Å; T79-F105 HydrophobicContact CG2-CG 4.49Å; T79-F105 HydrophobicContact CG2-CZ 4.47Å; T79-F105 PolarHBondContact OG1-N 2.7Å; F105-G112 VanDerWaalsContact CE1-C 3.46Å; F105-G112 WeakPolarHBondContact CE1-O 3.3Å; F105-G112 WeakPolarHBondContact CZ-O 3.4Å; F105-H139 PolarHBondContact O-NE2 3.3Å; F105-L167 HydrophobicContact CB-CD1 3.8Å; F105-L167 WeakPolarHBondContact O-CD1 3.42Å; F105-Q546 VanDerWaalsContact CE1-O 3.23Å; F105-Q546 WeakPolarHBondContact CE1-O 3.46Å; F105-Q546 HydrophobicContact CZ-CB 4.41Å; F105-L547 HydrophobicContact CD1-CD2 3.9Å; F105-L547 HydrophobicContact CE1-CD2 3.61Å; F105-L547 HydrophobicContact CE2-CD2 4.34Å; F105-L547 HydrophobicContact CG-CD2 4.36Å; F105-L547 HydrophobicContact CZ-CD2 3.84Å; F105-L547 HydrophobicContact CZ-CG 4.46Å; F105-I552 HydrophobicContact CD1-CG2 4.32Å; F105-I552 HydrophobicContact CE1-CG2 4.33Å
106I94.2Very high93.7Very high45 Ų4524.8 Ų24.823%0.23114%0.136CC..  trans-126.15.3179.563.5177.8000113V104 F181 N240V104-I106 HydrophobicContact CG2-CG2 4.16Å; I106-F181 HydrophobicContact CB-CZ 4.45Å; I106-F181 HydrophobicContact CD1-CE1 3.75Å; I106-F181 HydrophobicContact CD1-CZ 4.39Å; I106-F181 HydrophobicContact CG1-CE1 4.29Å; I106-N240 PolarHBondContact O-ND2 3.3Å
107F96.4Very high93.6Very high23 Ų2331.7 Ų31.710%0.10116%0.162CC..  trans-136.9137.4176.2-65.7-71000110.4A109 A110 F181 F232 I236 N240 I552 W554F107-A109 VanDerWaalsContact C-N 3.29Å; F107-A110 HydrophobicContact CB-CB 4.27Å; F107-A110 WeakPolarHBondContact O-CB 3.47Å; F107-A110 PolarHBondContact O-N 2.82Å; F107-F181 HydrophobicContact CD1-CZ 4.43Å; F107-F181 AromaticContact CE1-CE1 3.86Å; F107-F181 HydrophobicContact CE1-CE1 3.86Å; F107-F181 AromaticContact CE1-CZ 3.68Å; F107-F181 HydrophobicContact CE1-CZ 3.68Å; F107-F181 HydrophobicContact CE2-CE1 4.03Å; F107-F181 HydrophobicContact CE2-CZ 4.46Å; F107-F181 HydrophobicContact CZ-CD1 4.4Å; F107-F181 AromaticContact CZ-CE1 3.37Å; F107-F181 HydrophobicContact CZ-CE1 3.37Å; F107-F181 AromaticContact CZ-CZ 3.7Å; F107-F181 HydrophobicContact CZ-CZ 3.7Å; F107-F232 AromaticContact CE1-CZ 3.86Å; F107-F232 HydrophobicContact CE1-CZ 3.86Å; F107-F232 AromaticContact CZ-CZ 3.93Å; F107-F232 HydrophobicContact CZ-CZ 3.93Å; F107-I236 HydrophobicContact CE1-CD1 3.88Å; F107-N240 WeakPolarHBondContact CA-OD1 3.46Å; F107-I552 WeakPolarHBondContact CD2-O 3.42Å; F107-W554 HydrophobicContact CD1-CB 3.93Å; F107-W554 AromaticContact CD1-CD1 3.88Å; F107-W554 HydrophobicContact CD1-CG 4.19Å; F107-W554 HydrophobicContact CD2-CB 4Å; F107-W554 HydrophobicContact CE1-CB 4.09Å; F107-W554 HydrophobicContact CE1-CG 4.47Å; F107-W554 HydrophobicContact CE2-CB 4.16Å; F107-W554 HydrophobicContact CG-CB 3.89Å; F107-W554 HydrophobicContact CG-CG 4.47Å; F107-W554 HydrophobicContact CZ-CB 4.2Å
108N96.3Very high93.9Very high5 Ų531.7 Ų31.73%0.02716%0.162CC..THydrogen-bonded Turntrans-65.4-36.9168-77.6-36000111.7A110 P166 L167 L239 N240 I242 P560N108-A110 PolarHBondContact O-N 2.82Å; N108-P166 WeakPolarHBondContact OD1-CG 3.18Å; N108-L167 VanDerWaalsContact OD1-CB 3.26Å; N108-L167 WeakPolarHBondContact OD1-CB 3.45Å; N108-L239 PolarHBondContact ND2-O 2.51Å; N108-N240 PolarHBondContact N-OD1 2.65Å; N108-N240 VanDerWaalsContact N-OD1 3.11Å; N108-N240 VanDerWaalsContact ND2-C 3.32Å; N108-N240 VanDerWaalsContact ND2-CA 3.3Å; N108-N240 WeakPolarHBondContact ND2-CA 3.21Å; N108-N240 PolarHBondContact ND2-O 2.75Å; N108-I242 WeakPolarHBondContact ND2-CD1 3.47Å; N108-P560 HydrophobicContact CB-CG 4.02Å
109A97Very high94.3Very high0 Ų033.1 Ų33.10%017%0.17CC..THydrogen-bonded Turntrans-85.532.7178.700000112.7F107 K555 L558 Q559F107-A109 VanDerWaalsContact C-N 3.29Å; A109-K555 WeakPolarHBondContact CB-O 3.34Å; A109-K555 WeakPolarHBondContact O-CB 3.38Å; A109-K555 PolarHBondContact O-N 2.82Å; A109-L558 HydrophobicContact CB-CB 4.11Å; A109-Q559 HydrophobicContact CB-CB 3.92Å
110A97.4Very high94.8Very high2 Ų228.5 Ų28.52%0.01715%0.145CC..  trans-89.1153.1166.700000108.5F107 N108 H551F107-A110 HydrophobicContact CB-CB 4.27Å; F107-A110 WeakPolarHBondContact O-CB 3.47Å; F107-A110 PolarHBondContact O-N 2.82Å; N108-A110 PolarHBondContact O-N 2.82Å; A110-H551 WeakPolarHBondContact CB-O 3.27Å
111S97.8Very high95.4Very high10 Ų1025.2 Ų25.27%0.0713%0.128CC..SBendtrans-100.50.3179.177.20000114N143 C144 H152 H551 K555S111-N143 WeakPolarHBondContact CA-O 3.44Å; S111-C144 WeakPolarHBondContact CB-O 3.43Å; S111-H152 PolarHBondContact O-NE2 3.2Å; S111-H551 PolarHBondContact N-O 2.94Å; S111-H551 PolarHBondContact OG-CD2 2.75Å; S111-K555 PolarHBondContact OG-NZ 3.3Å
112G97.6Very high96Very high0 Ų020.3 Ų20.30%011%0.109CC..  trans-86.8149173.800000111.2F105 G141 H551F105-G112 VanDerWaalsContact CE1-C 3.46Å; F105-G112 WeakPolarHBondContact CE1-O 3.3Å; F105-G112 WeakPolarHBondContact CZ-O 3.4Å; G112-G141 WeakPolarHBondContact O-CA 3.26Å; G112-H551 PolarHBondContact N-O 3.48Å; G112-H551 VanDerWaalsContact N-O 3.1Å
113G98.1Very high96.8Very high0 Ų021 Ų210%011%0.107CC..  trans-173.6-171.2175.100000112.7L115 L140 H152 Q546G113-L115 PolarHBondContact O-N 2.97Å; G113-L140 CarbonylContact C-O 3.49Å; G113-L140 WeakPolarHBondContact CA-O 3.41Å; G113-H152 PolarHBondContact N-NE2 3.22Å; G113-Q546 WeakPolarHBondContact O-CB 3.45Å; G113-Q546 VanDerWaalsContact O-CG 3.26Å; G113-Q546 WeakPolarHBondContact O-CG 3.43Å
114L98.4Very high97.3Very high0 Ų021.2 Ų21.20%011%0.108CC..  trans-69.9120.9169.5-176.565.8000108.6A83 T87 V96 A116 E118 T120 W138 L140 H152 H157A83-L114 HydrophobicContact CB-CD1 4.38Å; T87-L114 HydrophobicContact CG2-CD1 4.15Å; T87-L114 HydrophobicContact CG2-CD2 4.29Å; V96-L114 HydrophobicContact CG2-CD1 4.1Å; L114-A116 PolarHBondContact O-N 2.98Å; L114-E118 HydrophobicContact CD1-CB 3.85Å; L114-E118 HydrophobicContact CD1-CG 3.83Å; L114-E118 HydrophobicContact CG-CB 4.16Å; L114-T120 HydrophobicContact CD2-CG2 3.95Å; L114-W138 HydrophobicContact CD2-CH2 4.43Å; L114-L140 HydrophobicContact CB-CB 4Å; L114-L140 HydrophobicContact CB-CD1 4.4Å; L114-L140 HydrophobicContact CD2-CD1 4.19Å; L114-L140 PolarHBondContact N-O 3.33Å; L114-H152 PolarHBondContact O-ND1 3.38Å; L114-H157 PolarHBondContact O-CE1 2.84Å; L114-H157 VanDerWaalsContact O-CE1 3.24Å; L114-H157 PolarHBondContact O-NE2 2.76Å; L114-H157 VanDerWaalsContact O-NE2 3.08Å
115L97.1Very high97.4Very high27 Ų2719.9 Ų19.914%0.14110%0.1CC..  trans-64.9137.5-176.8-65.7171.8000111.1G113 R117 E118 Q546G113-L115 PolarHBondContact O-N 2.97Å; L115-R117 HydrophobicContact CB-CG 4.03Å; L115-R117 VanDerWaalsContact CD1-NH2 3.31Å; L115-R117 PolarHBondContact O-N 3.26Å; L115-E118 WeakPolarHBondContact O-CB 3.28Å; L115-E118 PolarHBondContact O-N 3.49Å; L115-Q546 HydrophobicContact CD1-CG 4.46Å; L115-Q546 HydrophobicContact CD2-CG 4.3Å; L115-Q546 HydrophobicContact CG-CG 4.1Å
116A95.1Very high97.5Very high51 Ų5123.7 Ų23.742%0.42112%0.116SC..THydrogen-bonded Turntrans-59.2-18.3-178.500000115L114 K123L114-A116 PolarHBondContact O-N 2.98Å; A116-K123 PolarHBondContact O-NZ 3.31Å
117R95.6Very high97.6Very high144 Ų14428.7 Ų28.754%0.54314%0.138SC..THydrogen-bonded Turntrans-76.4-18.7173.572.3-179.9-179.9-156.7-4.2113.9L115 R418L115-R117 HydrophobicContact CB-CG 4.03Å; L115-R117 VanDerWaalsContact CD1-NH2 3.31Å; L115-R117 PolarHBondContact O-N 3.26Å; R117-R418 PolarHBondContact O-NH1 3.29Å; R117-R418 PolarHBondContact O-NH2 3.42Å
118E98Very high97.7Very high6 Ų630.5 Ų30.53%0.02815%0.147CC..SBendtrans-68.6140.6170.8-67.1-57.8133.200109.1T87 R89 L114 L115 R418T87-E118 HydrophobicContact CG2-CB 4.1Å; R89-E118 IonicContact CZ-OE2 3.18Å; R89-E118 IonicContact NE-OE2 2.74Å; R89-E118 PolarHBondContact NE-OE2 2.83Å; L114-E118 HydrophobicContact CD1-CB 3.85Å; L114-E118 HydrophobicContact CD1-CG 3.83Å; L114-E118 HydrophobicContact CG-CB 4.16Å; L115-E118 WeakPolarHBondContact O-CB 3.28Å; L115-E118 PolarHBondContact O-N 3.49Å; E118-R418 IonicContact OE2-NH1 3.3Å
119V98.2Very high97.7Very high30 Ų3032.6 Ų32.618%0.18217%0.171CC..  trans-105.1119.2-177.8177.60000106.9I124 F403 P415V119-I124 HydrophobicContact CG1-CD1 3.62Å; V119-I124 HydrophobicContact CG1-CG1 3.5Å; V119-F403 WeakPolarHBondContact O-CE2 3.37Å; V119-P415 HydrophobicContact CG1-CG 4.31Å
120T98.8Very high97.8Very high0 Ų032.7 Ų32.70%017%0.171CC..  trans-93.1158175.262.90000110.6L86 L114 A122 K123 I124 H157L86-T120 HydrophobicContact CB-CG2 3.94Å; L86-T120 CarbonylContact O-C 3.47Å; L86-T120 WeakPolarHBondContact O-CA 3.49Å; L114-T120 HydrophobicContact CD2-CG2 3.95Å; T120-A122 PolarHBondContact O-N 2.95Å; T120-K123 PolarHBondContact O-N 2.84Å; T120-K123 WeakPolarHBondContact OG1-CB 3.35Å; T120-K123 PolarHBondContact OG1-N 3.27Å; T120-K123 VanDerWaalsContact OG1-N 3.09Å; T120-I124 PolarHBondContact O-N 2.88Å; T120-H157 HydrophobicContact CG2-CB 3.99Å; T120-H157 PolarHBondContact OG1-O 3.43Å
121F98.8Very high97.9Very high0 Ų034.9 Ų34.90%018%0.182CC..Hα-helixtrans-58.2-34.217258.1-112.4000111.1L34 F85 L86 K123 I124 V125 L280 F403 I406L34-F121 HydrophobicContact CD1-CD2 4.35Å; L34-F121 HydrophobicContact CD1-CE1 4.22Å; L34-F121 HydrophobicContact CD1-CE2 3.5Å; L34-F121 VanDerWaalsContact CD1-CE2 3.5Å; L34-F121 HydrophobicContact CD1-CZ 3.41Å; L34-F121 VanDerWaalsContact CD1-CZ 3.41Å; F85-F121 AromaticContact CD1-CE1 3.98Å; F85-F121 HydrophobicContact CD1-CE1 3.98Å; F85-F121 HydrophobicContact CD1-CZ 4.23Å; F85-F121 AromaticContact CE1-CE1 3.69Å; F85-F121 HydrophobicContact CE1-CE1 3.69Å; F85-F121 AromaticContact CE1-CZ 3.6Å; F85-F121 HydrophobicContact CE1-CZ 3.6Å; F85-F121 HydrophobicContact CE2-CE1 4.47Å; F85-F121 AromaticContact CZ-CE1 3.96Å; F85-F121 HydrophobicContact CZ-CE1 3.96Å; F85-F121 HydrophobicContact CZ-CZ 4.01Å; F85-F121 WeakPolarHBondContact O-CE1 3.34Å; L86-F121 HydrophobicContact CD2-CE1 3.75Å; L86-F121 HydrophobicContact CD2-CE2 4.22Å; L86-F121 HydrophobicContact CD2-CZ 3.51Å; L86-F121 WeakPolarHBondContact O-CD1 3.47Å; L86-F121 PolarHBondContact O-N 2.97Å; F121-K123 PolarHBondContact O-N 3.38Å; F121-I124 PolarHBondContact O-N 2.87Å; F121-V125 WeakPolarHBondContact O-CG1 3.41Å; F121-V125 PolarHBondContact O-N 3.19Å; F121-L280 HydrophobicContact CD2-CD1 3.59Å; F121-L280 HydrophobicContact CE2-CD1 3.75Å; F121-L280 HydrophobicContact CE2-CD2 4.05Å; F121-F403 HydrophobicContact CB-CD2 3.8Å; F121-F403 HydrophobicContact CB-CE2 4.31Å; F121-F403 HydrophobicContact CD1-CD2 4.33Å; F121-I406 HydrophobicContact CB-CB 4.34Å; F121-I406 HydrophobicContact CB-CD1 4.41Å; F121-I406 HydrophobicContact CB-CG2 4.1Å; F121-I406 HydrophobicContact CD1-CD1 4.17Å; F121-I406 HydrophobicContact CD2-CD1 3.94Å; F121-I406 HydrophobicContact CE1-CD1 4.42Å; F121-I406 HydrophobicContact CE2-CD1 4.28Å; F121-I406 HydrophobicContact CG-CD1 3.93Å; F121-I406 HydrophobicContact CZ-CD1 4.49Å
122A98.8Very high97.9Very high0 Ų034.4 Ų34.40%018%0.179CC..Hα-helixtrans-62.3-43.717800000111.5T120 I124 V125 K126 F159T120-A122 PolarHBondContact O-N 2.95Å; A122-I124 VanDerWaalsContact C-N 3.3Å; A122-I124 PolarHBondContact O-N 3.11Å; A122-V125 PolarHBondContact O-N 2.99Å; A122-K126 WeakPolarHBondContact O-CB 3.38Å; A122-K126 PolarHBondContact O-N 2.74Å; A122-F159 HydrophobicContact CB-CD1 4.07Å; A122-F159 HydrophobicContact CB-CD2 4.23Å; A122-F159 HydrophobicContact CB-CE1 3.7Å; A122-F159 HydrophobicContact CB-CE2 3.85Å; A122-F159 HydrophobicContact CB-CG 4.34Å; A122-F159 HydrophobicContact CB-CZ 3.57Å
123K98.5Very high98Very high62 Ų6234.4 Ų34.427%0.2718%0.179SC..Hα-helixtrans-62.6-37.4176.5-166.5164.9-172.7160.80112A116 T120 F121 Q127 V156A116-K123 PolarHBondContact O-NZ 3.31Å; T120-K123 PolarHBondContact O-N 2.84Å; T120-K123 WeakPolarHBondContact OG1-CB 3.35Å; T120-K123 PolarHBondContact OG1-N 3.27Å; T120-K123 VanDerWaalsContact OG1-N 3.09Å; F121-K123 PolarHBondContact O-N 3.38Å; K123-Q127 WeakPolarHBondContact O-CG 3.42Å; K123-V156 PolarHBondContact NZ-O 3.47Å
124I98.6Very high98Very high10 Ų1034.4 Ų34.45%0.05118%0.179CC..Hα-helixtrans-70.2-52.3177.5-65.4172.6000111V119 T120 F121 A122 K126 Q127 Q128 F403 V407 A412 P415V119-I124 HydrophobicContact CG1-CD1 3.62Å; V119-I124 HydrophobicContact CG1-CG1 3.5Å; T120-I124 PolarHBondContact O-N 2.88Å; F121-I124 PolarHBondContact O-N 2.87Å; A122-I124 VanDerWaalsContact C-N 3.3Å; A122-I124 PolarHBondContact O-N 3.11Å; I124-K126 VanDerWaalsContact C-N 3.28Å; I124-K126 PolarHBondContact O-N 2.87Å; I124-Q127 WeakPolarHBondContact O-CB 3.41Å; I124-Q127 PolarHBondContact O-N 2.76Å; I124-Q127 VanDerWaalsContact O-N 3.07Å; I124-Q128 PolarHBondContact O-N 3.39Å; I124-F403 HydrophobicContact CD1-CE1 4.4Å; I124-F403 HydrophobicContact CD1-CE2 4Å; I124-F403 HydrophobicContact CD1-CZ 3.56Å; I124-V407 HydrophobicContact CB-CG2 4.36Å; I124-V407 HydrophobicContact CD1-CG2 3.54Å; I124-V407 HydrophobicContact CG2-CG1 4.24Å; I124-V407 HydrophobicContact CG2-CG2 4.1Å; I124-A412 HydrophobicContact CG2-CB 3.31Å; I124-P415 HydrophobicContact CD1-CG 4.02Å
125V98.5Very high98.1Very high0 Ų034.4 Ų34.40%018%0.179CC..Hα-helixtrans-68.1-30.4-176.6-56.30000112.4F32 F121 A122 Q127 Q128 G129 Y130 T132 L280 I406F32-V125 HydrophobicContact CE2-CG1 4.28Å; F121-V125 WeakPolarHBondContact O-CG1 3.41Å; F121-V125 PolarHBondContact O-N 3.19Å; A122-V125 PolarHBondContact O-N 2.99Å; V125-Q127 VanDerWaalsContact C-N 3.25Å; V125-Q127 PolarHBondContact O-N 3.47Å; V125-Q128 CarbonylContact O-C 3.47Å; V125-Q128 VanDerWaalsContact O-CA 3.26Å; V125-Q128 WeakPolarHBondContact O-CA 3.12Å; V125-Q128 VanDerWaalsContact O-CB 3.28Å; V125-Q128 WeakPolarHBondContact O-CB 3.35Å; V125-Q128 PolarHBondContact O-N 3Å; V125-G129 PolarHBondContact O-N 3.33Å; V125-Y130 HydrophobicContact CB-CD1 4.39Å; V125-Y130 HydrophobicContact CB-CD2 3.84Å; V125-Y130 HydrophobicContact CB-CE2 4.38Å; V125-Y130 HydrophobicContact CB-CG 3.85Å; V125-Y130 HydrophobicContact CG2-CG 4.15Å; V125-Y130 WeakPolarHBondContact O-CB 3.32Å; V125-Y130 VanDerWaalsContact O-CD2 3.28Å; V125-Y130 WeakPolarHBondContact O-CD2 3.37Å; V125-Y130 PolarHBondContact O-N 2.93Å; V125-T132 HydrophobicContact CG2-CG2 3.86Å; V125-L280 HydrophobicContact CG2-CB 4.11Å; V125-L280 HydrophobicContact CG2-CD1 3.75Å; V125-I406 HydrophobicContact CG1-CG2 3.4Å; V125-I406 VanDerWaalsContact CG1-CG2 3.4Å
126K98.3Very high98.1Very high82 Ų8233.1 Ų33.136%0.35717%0.172SC..Hα-helixtrans-57.8-39.4171.5178.8168.5170.3165.60111.7A122 I124 Q128 G129 T132 G158 D160A122-K126 WeakPolarHBondContact O-CB 3.38Å; A122-K126 PolarHBondContact O-N 2.74Å; I124-K126 VanDerWaalsContact C-N 3.28Å; I124-K126 PolarHBondContact O-N 2.87Å; K126-Q128 PolarHBondContact O-N 2.98Å; K126-G129 PolarHBondContact O-N 2.84Å; K126-T132 HydrophobicContact CB-CG2 4.11Å; K126-G158 WeakPolarHBondContact CD-O 3.3Å; K126-D160 WeakPolarHBondContact CD-OD1 3.42Å; K126-D160 WeakPolarHBondContact CE-OD1 3.47Å; K126-D160 IonicContact NZ-OD1 2.77Å; K126-D160 PolarHBondContact NZ-OD1 2.98Å
127Q97.4Very high98.3Very high150 Ų15030.7 Ų30.770%0.70115%0.152SC*.Hα-helixtrans-66.9-22.5172.9-65.1172.2-1.200112.7K123 I124 V125 G129K123-Q127 WeakPolarHBondContact O-CG 3.42Å; I124-Q127 WeakPolarHBondContact O-CB 3.41Å; I124-Q127 PolarHBondContact O-N 2.76Å; I124-Q127 VanDerWaalsContact O-N 3.07Å; V125-Q127 VanDerWaalsContact C-N 3.25Å; V125-Q127 PolarHBondContact O-N 3.47Å; Q127-G129 PolarHBondContact O-N 3.17Å
128Q97.6Very high98.5Very high61 Ų6123.9 Ų23.929%0.28513%0.126SC..THydrogen-bonded Turntrans-84.48.3172.5-60.9-55.1-39.200113.5K29 I124 V125 K126 Y130 A412K29-Q128 PolarHBondContact NZ-O 2.72Å; I124-Q128 PolarHBondContact O-N 3.39Å; V125-Q128 CarbonylContact O-C 3.47Å; V125-Q128 VanDerWaalsContact O-CA 3.26Å; V125-Q128 WeakPolarHBondContact O-CA 3.12Å; V125-Q128 VanDerWaalsContact O-CB 3.28Å; V125-Q128 WeakPolarHBondContact O-CB 3.35Å; V125-Q128 PolarHBondContact O-N 3Å; K126-Q128 PolarHBondContact O-N 2.98Å; Q128-Y130 HydrophobicContact CB-CD2 3.99Å; Q128-Y130 HydrophobicContact CB-CE2 4.2Å; Q128-A412 HydrophobicContact CG-CB 3.83Å
129G97.1Very high98.5Very high50 Ų5023.7 Ų23.752%0.51513%0.125SC..THydrogen-bonded Turntrans83.717.3176.600000114.5V125 K126 Q127V125-G129 PolarHBondContact O-N 3.33Å; K126-G129 PolarHBondContact O-N 2.84Å; Q127-G129 PolarHBondContact O-N 3.17Å
130Y98.6Very high98.5Very high2 Ų222.2 Ų22.21%0.00812%0.117CC..  trans-76.5140171.7-77.1-112000110.9K29 P30 F32 V125 Q128 P278 L280K29-Y130 HydrophobicContact CB-CE2 4.26Å; K29-Y130 WeakPolarHBondContact CB-OH 3.46Å; K29-Y130 HydrophobicContact CD-CE2 3.95Å; K29-Y130 HydrophobicContact CG-CE2 4.42Å; P30-Y130 WeakPolarHBondContact O-CE1 3.35Å; P30-Y130 VanDerWaalsContact O-CZ 3.3Å; P30-Y130 PolarHBondContact O-OH 3.11Å; F32-Y130 HydrophobicContact CD2-CD1 4.06Å; F32-Y130 AromaticContact CD2-CE1 3.46Å; F32-Y130 HydrophobicContact CD2-CE1 3.46Å; F32-Y130 VanDerWaalsContact CD2-CE1 3.46Å; F32-Y130 HydrophobicContact CE2-CD1 4.18Å; F32-Y130 AromaticContact CE2-CE1 3.3Å; F32-Y130 HydrophobicContact CE2-CE1 3.3Å; F32-Y130 HydrophobicContact CE2-CE2 4.42Å; F32-Y130 AromaticContact CE2-CZ 3.46Å; F32-Y130 VanDerWaalsContact CE2-CZ 3.46Å; F32-Y130 WeakPolarHBondContact CE2-OH 3.45Å; F32-Y130 HydrophobicContact CZ-CE1 4.39Å; V125-Y130 HydrophobicContact CB-CD1 4.39Å; V125-Y130 HydrophobicContact CB-CD2 3.84Å; V125-Y130 HydrophobicContact CB-CE2 4.38Å; V125-Y130 HydrophobicContact CB-CG 3.85Å; V125-Y130 HydrophobicContact CG2-CG 4.15Å; V125-Y130 WeakPolarHBondContact O-CB 3.32Å; V125-Y130 VanDerWaalsContact O-CD2 3.28Å; V125-Y130 WeakPolarHBondContact O-CD2 3.37Å; V125-Y130 PolarHBondContact O-N 2.93Å; Q128-Y130 HydrophobicContact CB-CD2 3.99Å; Q128-Y130 HydrophobicContact CB-CE2 4.2Å; Y130-P278 WeakPolarHBondContact CA-O 3.28Å; Y130-P278 HydrophobicContact CD1-CB 3.87Å; Y130-P278 HydrophobicContact CD2-CB 4.29Å; Y130-P278 HydrophobicContact CE1-CB 3.7Å; Y130-P278 HydrophobicContact CE2-CB 4.16Å; Y130-P278 HydrophobicContact CG-CB 4.15Å; Y130-L280 HydrophobicContact CD1-CB 4.48Å
131N98.6Very high98.4Very high47 Ų4722.8 Ų22.825%0.25112%0.122SC..EExtended strand (participates in β ladder)trans-80.8130.1161.6-72.3-14.8000108.7F270 N274 P278 F279 L280N131-F270 HydrophobicContact CB-CZ 4.45Å; N131-N274 WeakPolarHBondContact CB-OD1 3.34Å; N131-N274 PolarHBondContact ND2-OD1 3.32Å; N131-P278 PolarHBondContact N-O 2.67Å; N131-P278 VanDerWaalsContact N-O 3.13Å; N131-F279 CarbonylContact O-C 3.54Å; N131-F279 VanDerWaalsContact O-CA 3.23Å; N131-F279 WeakPolarHBondContact O-CA 3.34Å; N131-L280 PolarHBondContact O-N 2.95Å
132T98.9Very high98.4Very high0 Ų022.8 Ų22.80%012%0.122CC..EExtended strand (participates in β ladder)trans-121.3133.3-171.659.20000112.4V125 K126 G158 F159 D160 Y161 L280V125-T132 HydrophobicContact CG2-CG2 3.86Å; K126-T132 HydrophobicContact CB-CG2 4.11Å; T132-G158 WeakPolarHBondContact CB-O 3.45Å; T132-G158 PolarHBondContact OG1-O 2.98Å; T132-F159 VanDerWaalsContact OG1-CA 3.23Å; T132-F159 WeakPolarHBondContact OG1-CA 3.17Å; T132-D160 PolarHBondContact N-OD2 2.76Å; T132-D160 VanDerWaalsContact N-OD2 3.09Å; T132-D160 WeakPolarHBondContact O-CA 3.45Å; T132-D160 WeakPolarHBondContact O-CB 3.49Å; T132-D160 PolarHBondContact O-N 3.38Å; T132-D160 PolarHBondContact OG1-N 2.85Å; T132-D160 PolarHBondContact OG1-OD2 3.07Å; T132-Y161 PolarHBondContact O-N 2.87Å; T132-L280 CarbonylContact C-O 3.57Å; T132-L280 VanDerWaalsContact CA-O 3.32Å; T132-L280 WeakPolarHBondContact CA-O 3.48Å; T132-L280 HydrophobicContact CG2-CB 4.15Å
133A98.9Very high98.4Very high0 Ų022.8 Ų22.80%012%0.122CC..EExtended strand (participates in β ladder)trans-130.3140.7175.700000112F159 Y161 F270 L280 L281 F282A133-F159 VanDerWaalsContact C-CD1 3.44Å; A133-Y161 WeakPolarHBondContact CA-O 3.36Å; A133-Y161 HydrophobicContact CB-CD1 4.09Å; A133-F270 HydrophobicContact CB-CD1 3.91Å; A133-F270 HydrophobicContact CB-CD2 3.56Å; A133-F270 HydrophobicContact CB-CE1 3.78Å; A133-F270 HydrophobicContact CB-CE2 3.43Å; A133-F270 VanDerWaalsContact CB-CE2 3.43Å; A133-F270 HydrophobicContact CB-CG 3.79Å; A133-F270 HydrophobicContact CB-CZ 3.54Å; A133-L280 PolarHBondContact N-O 3.4Å; A133-L281 HydrophobicContact CB-CD1 4.08Å; A133-F282 PolarHBondContact O-N 3.09Å
134L98.9Very high98.3Very high0 Ų021.8 Ų21.80%012%0.122CC..EExtended strand (participates in β ladder)trans-110.7126162.8171.763.7000108.5W138 P154 F159 Y161 F162 F163 F282L134-W138 HydrophobicContact CD2-CB 4.16Å; L134-W138 HydrophobicContact CD2-CD2 4.16Å; L134-W138 HydrophobicContact CD2-CE3 3.5Å; L134-W138 VanDerWaalsContact CD2-CE3 3.5Å; L134-W138 HydrophobicContact CD2-CG 4.47Å; L134-W138 HydrophobicContact CD2-CZ3 4.19Å; L134-P154 HydrophobicContact CD2-CB 3.79Å; L134-P154 HydrophobicContact CD2-CG 3.54Å; L134-F159 HydrophobicContact CB-CB 4.37Å; L134-F159 HydrophobicContact CB-CD1 3.78Å; L134-F159 HydrophobicContact CB-CD2 4.15Å; L134-F159 HydrophobicContact CB-CE1 4.03Å; L134-F159 HydrophobicContact CB-CE2 4.39Å; L134-F159 HydrophobicContact CB-CG 3.83Å; L134-F159 HydrophobicContact CB-CZ 4.34Å; L134-Y161 PolarHBondContact N-O 3.48Å; L134-F162 HydrophobicContact CB-CD2 4.01Å; L134-F162 HydrophobicContact CD2-CD2 3.74Å; L134-F162 HydrophobicContact CD2-CE2 3.73Å; L134-F162 HydrophobicContact CG-CD2 3.77Å; L134-F162 HydrophobicContact CG-CE2 3.95Å; L134-F162 WeakPolarHBondContact O-CA 3.36Å; L134-F162 WeakPolarHBondContact O-CD2 3.43Å; L134-F163 PolarHBondContact O-N 3.33Å; L134-F282 WeakPolarHBondContact CA-O 3.16Å; L134-F282 HydrophobicContact CD1-CB 4.11Å; L134-F282 HydrophobicContact CD1-CD1 3.38Å; L134-F282 HydrophobicContact CD1-CE1 3.88Å; L134-F282 HydrophobicContact CD1-CG 3.84Å
135I98.9Very high98.2Very high0 Ų029.1 Ų29.10%016%0.156CC..EExtended strand (participates in β ladder)trans-123.7118.9176-59.7-180000108.8F163 M263 E266 A267 L281 F282 L283 S284I135-F163 CarbonylContact C-O 3.6Å; I135-F163 VanDerWaalsContact CA-O 3.26Å; I135-F163 WeakPolarHBondContact CA-O 3.43Å; I135-F163 HydrophobicContact CG2-CD1 4.26Å; I135-M263 HydrophobicContact CG2-CB 3.87Å; I135-M263 HydrophobicContact CG2-CE 4.43Å; I135-M263 HydrophobicContact CG2-CG 4.11Å; I135-E266 VanDerWaalsContact CD1-C 3.42Å; I135-E266 HydrophobicContact CD1-CB 3.88Å; I135-E266 HydrophobicContact CG2-CB 4.31Å; I135-A267 HydrophobicContact CD1-CB 3.82Å; I135-A267 VanDerWaalsContact CD1-N 3.3Å; I135-L281 HydrophobicContact CB-CD1 4.45Å; I135-L281 HydrophobicContact CD1-CD1 3.68Å; I135-L281 HydrophobicContact CG1-CD1 3.96Å; I135-F282 PolarHBondContact N-O 3.47Å; I135-L283 HydrophobicContact CB-CD1 3.84Å; I135-L283 HydrophobicContact CG2-CD1 3.71Å; I135-S284 PolarHBondContact O-N 2.87Å
136G98.6Very high98Very high0 Ų031.3 Ų31.30%017%0.172CC..EExtended strand (participates in β ladder)trans105.8-133.2178.300000114.8F163 G164 I165 S284G136-F163 PolarHBondContact N-O 3.27Å; G136-G164 CarbonylContact O-C 3.43Å; G136-G164 VanDerWaalsContact O-CA 3.28Å; G136-G164 WeakPolarHBondContact O-CA 3.36Å; G136-I165 PolarHBondContact O-N 3.26Å; G136-S284 CarbonylContact C-O 3.25Å; G136-S284 VanDerWaalsContact CA-O 3.24Å; G136-S284 WeakPolarHBondContact CA-O 3.26Å
137K98.8Very high97.8Very high0 Ų029.9 Ų29.90%017%0.172CC..EExtended strand (participates in β ladder)trans-78129.6-169.8176176.2170.6-179.30112.8D38 C78 R82 H139 I165 T168 S284 L286D38-K137 IonicContact OD1-NZ 3.16Å; D38-K137 PolarHBondContact OD1-NZ 2.9Å; D38-K137 WeakPolarHBondContact OD2-CD 3.18Å; D38-K137 WeakPolarHBondContact OD2-CE 3.25Å; D38-K137 IonicContact OD2-NZ 3.55Å; D38-K137 PolarHBondContact OD2-NZ 3.46Å; C78-K137 PolarHBondContact SG-NZ 3.06Å; R82-K137 PolarHBondContact NH1-O 3.45Å; K137-H139 HydrophobicContact CD-CB 4.45Å; K137-H139 WeakPolarHBondContact CE-ND1 3.38Å; K137-H139 HydrophobicContact CG-CB 4.06Å; K137-I165 HydrophobicContact CB-CG1 4.32Å; K137-T168 WeakPolarHBondContact CE-OG1 3.49Å; K137-T168 PolarHBondContact NZ-OG1 2.98Å; K137-S284 PolarHBondContact N-O 2.98Å; K137-S284 WeakPolarHBondContact O-CB 3.23Å; K137-S284 PolarHBondContact O-OG 3.29Å; K137-L286 HydrophobicContact CB-CD1 4.14Å
138W98.7Very high97.7Very high2 Ų228.1 Ų28.11%0.00817%0.168CC..  trans-94.7-66.5171.8177.8-130.8000112.5L86 L114 L134 L140 G141 H152 P154 H157 F159 F162 I165L86-W138 HydrophobicContact CD1-CE3 4.26Å; L86-W138 HydrophobicContact CD1-CH2 3.48Å; L86-W138 VanDerWaalsContact CD1-CH2 3.48Å; L86-W138 HydrophobicContact CD1-CZ3 3.23Å; L114-W138 HydrophobicContact CD2-CH2 4.43Å; L134-W138 HydrophobicContact CD2-CB 4.16Å; L134-W138 HydrophobicContact CD2-CD2 4.16Å; L134-W138 HydrophobicContact CD2-CE3 3.5Å; L134-W138 VanDerWaalsContact CD2-CE3 3.5Å; L134-W138 HydrophobicContact CD2-CG 4.47Å; L134-W138 HydrophobicContact CD2-CZ3 4.19Å; W138-L140 HydrophobicContact CD2-CB 4.05Å; W138-L140 HydrophobicContact CD2-CD1 4.3Å; W138-L140 HydrophobicContact CD2-CG 4.46Å; W138-L140 HydrophobicContact CE3-CD1 4.11Å; W138-L140 HydrophobicContact CG-CB 4.47Å; W138-L140 HydrophobicContact CH2-CB 4.4Å; W138-L140 HydrophobicContact CH2-CD1 3.66Å; W138-L140 HydrophobicContact CZ2-CB 3.7Å; W138-L140 HydrophobicContact CZ2-CD1 3.84Å; W138-L140 HydrophobicContact CZ2-CG 4.37Å; W138-L140 HydrophobicContact CZ3-CD1 3.83Å; W138-G141 VanDerWaalsContact CD1-O 3.24Å; W138-G141 PolarHBondContact NE1-O 3.13Å; W138-H152 PolarHBondContact NE1-O 3Å; W138-P154 HydrophobicContact CB-CG 4.22Å; W138-P154 HydrophobicContact CD2-CG 3.71Å; W138-P154 HydrophobicContact CE3-CG 4.08Å; W138-P154 HydrophobicContact CG-CG 3.77Å; W138-H157 HydrophobicContact CH2-CB 3.92Å; W138-H157 HydrophobicContact CZ2-CB 4.28Å; W138-H157 AromaticContact CZ2-CD2 3.5Å; W138-F159 HydrophobicContact CZ3-CE2 4.06Å; W138-F162 HydrophobicContact CB-CZ 4.44Å; W138-I165 PolarHBondContact N-O 3.27Å
139H98.5Very high97.6Very high1 Ų127.8 Ų27.81%0.00517%0.168CC..  trans6529176.5-150-175.5000116.8C78 T79 F105 K137 P166 L167C78-H139 VanDerWaalsContact CB-ND1 3.26Å; C78-H139 WeakPolarHBondContact CB-ND1 3.28Å; T79-H139 PolarHBondContact OG1-CD2 3.03Å; T79-H139 VanDerWaalsContact OG1-CD2 3.29Å; T79-H139 PolarHBondContact OG1-CE1 3.32Å; T79-H139 PolarHBondContact OG1-ND1 3.32Å; T79-H139 PolarHBondContact OG1-NE2 3.48Å; T79-H139 PolarHBondContact OG1-O 3.3Å; F105-H139 PolarHBondContact O-NE2 3.3Å; K137-H139 HydrophobicContact CD-CB 4.45Å; K137-H139 WeakPolarHBondContact CE-ND1 3.38Å; K137-H139 HydrophobicContact CG-CB 4.06Å; H139-P166 WeakPolarHBondContact CA-O 3.29Å; H139-P166 PolarHBondContact N-O 3.34Å; H139-L167 VanDerWaalsContact CA-O 3.24Å; H139-L167 WeakPolarHBondContact CA-O 3.19Å; H139-L167 WeakPolarHBondContact CB-O 3.32Å; H139-L167 PolarHBondContact N-O 2.68Å
140L98.6Very high97.6Very high0 Ų026.6 Ų26.60%015%0.149CC..SBendtrans-129.433.8-177.1-63.5172.1000112.9T79 R82 A83 L86 V96 G113 L114 W138T79-L140 HydrophobicContact CG2-CD2 4.19Å; T79-L140 VanDerWaalsContact O-CD2 3.27Å; T79-L140 WeakPolarHBondContact O-CD2 3.28Å; R82-L140 HydrophobicContact CB-CD1 4.37Å; R82-L140 HydrophobicContact CB-CD2 4.43Å; R82-L140 HydrophobicContact CB-CG 4.48Å; A83-L140 HydrophobicContact CB-CD2 3.72Å; L86-L140 HydrophobicContact CD1-CD1 3.39Å; V96-L140 HydrophobicContact CG1-CD2 4.36Å; G113-L140 CarbonylContact C-O 3.49Å; G113-L140 WeakPolarHBondContact CA-O 3.41Å; L114-L140 HydrophobicContact CB-CB 4Å; L114-L140 HydrophobicContact CB-CD1 4.4Å; L114-L140 HydrophobicContact CD2-CD1 4.19Å; L114-L140 PolarHBondContact N-O 3.33Å; W138-L140 HydrophobicContact CD2-CB 4.05Å; W138-L140 HydrophobicContact CD2-CD1 4.3Å; W138-L140 HydrophobicContact CD2-CG 4.46Å; W138-L140 HydrophobicContact CE3-CD1 4.11Å; W138-L140 HydrophobicContact CG-CB 4.47Å; W138-L140 HydrophobicContact CH2-CB 4.4Å; W138-L140 HydrophobicContact CH2-CD1 3.66Å; W138-L140 HydrophobicContact CZ2-CB 3.7Å; W138-L140 HydrophobicContact CZ2-CD1 3.84Å; W138-L140 HydrophobicContact CZ2-CG 4.37Å; W138-L140 HydrophobicContact CZ3-CD1 3.83Å
141G97.9Very high97.6Very high11 Ų1127.8 Ų27.811%0.11316%0.157CC..  trans86.7172179.400000113.3G112 W138G112-G141 WeakPolarHBondContact O-CA 3.26Å; W138-G141 VanDerWaalsContact CD1-O 3.24Å; W138-G141 PolarHBondContact NE1-O 3.13Å
142L97.9Very high97.6Very high1 Ų125.8 Ų25.81%0.00515%0.146CC..  trans-132.9-64.1-180-177.762.5000111.7H150 C151 H152 H153 P166 F244 P560L142-H150 CarbonylContact O-C 3.47Å; L142-H150 WeakPolarHBondContact O-CA 3.31Å; L142-C151 PolarHBondContact O-N 3.29Å; L142-H152 PolarHBondContact O-N 2.83Å; L142-H153 HydrophobicContact CD1-CB 4.48Å; L142-P166 HydrophobicContact CB-CB 4.39Å; L142-P166 HydrophobicContact CD1-CB 4.05Å; L142-P166 HydrophobicContact CD2-CB 4.46Å; L142-P166 HydrophobicContact CD2-CG 4.32Å; L142-F244 HydrophobicContact CD1-CZ 4.39Å; L142-F244 HydrophobicContact CD2-CE2 4.41Å; L142-F244 HydrophobicContact CD2-CZ 4.02Å; L142-P560 HydrophobicContact CD2-CB 4.22Å; L142-P560 HydrophobicContact CD2-CG 3.8Å
143N97.8Very high97.5Very high0 Ų025.8 Ų25.80%015%0.146CC..  trans-121.7159.7-170.9-69.2-37.2000111.9S111 S146 S147 D149 H150 L558S111-N143 WeakPolarHBondContact CA-O 3.44Å; N143-S146 VanDerWaalsContact CB-O 3.27Å; N143-S146 WeakPolarHBondContact CB-O 3.49Å; N143-S147 VanDerWaalsContact ND2-C 3.31Å; N143-S147 PolarHBondContact ND2-O 2.97Å; N143-D149 VanDerWaalsContact CA-OD1 3.25Å; N143-D149 WeakPolarHBondContact CA-OD1 3.3Å; N143-H150 WeakPolarHBondContact OD1-CA 3.46Å; N143-H150 PolarHBondContact OD1-N 2.86Å; N143-L558 HydrophobicContact CB-CD2 4.33Å; N143-L558 PolarHBondContact ND2-O 3.21Å
144C96.3Very high97.5Very high40 Ų4025.8 Ų25.827%0.2715%0.146SC..SBendtrans-113.2-58.3-179.7-74.90000112.4S111 D149 C151 H152S111-C144 WeakPolarHBondContact CB-O 3.43Å; C144-D149 PolarHBondContact N-OD1 2.89Å; C144-D149 PolarHBondContact N-OD2 3.12Å; C144-C151 WeakPolarHBondContact CA-SG 3.38Å; C144-C151 HydrophobicContact CB-CB 3.78Å; C144-C151 WeakPolarHBondContact CB-SG 3.46Å; C144-C151 PolarHBondContact N-SG 2.94Å; C144-C151 WeakPolarHBondContact SG-CB 3.25Å; C144-C151 CovalentContact SG-SG 2Å; C144-C151 PolarHBondContact SG-SG 3.23Å; C144-H152 PolarHBondContact SG-NE2 3.38Å; C144-H152 VanDerWaalsContact SG-NE2 3.35Å
145E96.4Very high97.5Very high164 Ų16427.4 Ų27.477%0.76616%0.157SC*.SBendtrans-117.8-33.4-168.6-61.9-173170.400112D149 L558E145-D149 WeakPolarHBondContact CA-OD2 3.42Å; E145-D149 PolarHBondContact N-OD2 3.49Å; E145-L558 WeakPolarHBondContact O-CD2 3.43Å
146S96.2Very high97.4Very high46 Ų4629.9 Ų29.932%0.32217%0.172SC..SBendtrans-137157.2-178.259.30000111.8N143 D148 D149N143-S146 VanDerWaalsContact CB-O 3.27Å; N143-S146 WeakPolarHBondContact CB-O 3.49Å; S146-D148 PolarHBondContact O-N 3.26Å; S146-D148 PolarHBondContact OG-OD1 2.93Å; S146-D149 PolarHBondContact N-OD2 2.87Å; S146-D149 PolarHBondContact O-N 3.18Å; S146-D149 WeakPolarHBondContact OG-CB 3.4Å; S146-D149 PolarHBondContact OG-OD2 2.76Å
147S93.9Very high97.4Very high53 Ų5329.9 Ų29.937%0.37117%0.172SC..THydrogen-bonded Turntrans-64.6-9.2-175.852.20000115.3N143 W557N143-S147 VanDerWaalsContact ND2-C 3.31Å; N143-S147 PolarHBondContact ND2-O 2.97Å; S147-W557 PolarHBondContact N-O 3.04Å
148D94.2Very high97.4Very high113 Ų11330 Ų3060%0.60417%0.174SC*.THydrogen-bonded Turntrans-128.43.9-173.562.6-31.4000114.3S146 H150S146-D148 PolarHBondContact O-N 3.26Å; S146-D148 PolarHBondContact OG-OD1 2.93Å; D148-H150 VanDerWaalsContact C-N 3.34Å; D148-H150 VanDerWaalsContact C-ND1 3.35Å; D148-H150 PolarHBondContact O-N 3.28Å; D148-H150 PolarHBondContact O-ND1 3.35Å
149D96.3Very high97.4Very high54 Ų5430.1 Ų30.129%0.28918%0.175SC..  trans-72.7-24.5179.16441.2000114.3N143 C144 E145 S146 C151N143-D149 VanDerWaalsContact CA-OD1 3.25Å; N143-D149 WeakPolarHBondContact CA-OD1 3.3Å; C144-D149 PolarHBondContact N-OD1 2.89Å; C144-D149 PolarHBondContact N-OD2 3.12Å; E145-D149 WeakPolarHBondContact CA-OD2 3.42Å; E145-D149 PolarHBondContact N-OD2 3.49Å; S146-D149 PolarHBondContact N-OD2 2.87Å; S146-D149 PolarHBondContact O-N 3.18Å; S146-D149 WeakPolarHBondContact OG-CB 3.4Å; S146-D149 PolarHBondContact OG-OD2 2.76Å; D149-C151 PolarHBondContact O-N 2.86Å; D149-C151 VanDerWaalsContact O-N 3.08Å; D149-C151 PolarHBondContact OD1-N 3.32Å
150H97.1Very high97.4Very high24 Ų2433.5 Ų33.511%0.11119%0.193CC..  trans51.932.5176.7-65.497.9000113.8L142 N143 D148 H152 H153 F244 H247L142-H150 CarbonylContact O-C 3.47Å; L142-H150 WeakPolarHBondContact O-CA 3.31Å; N143-H150 WeakPolarHBondContact OD1-CA 3.46Å; N143-H150 PolarHBondContact OD1-N 2.86Å; D148-H150 VanDerWaalsContact C-N 3.34Å; D148-H150 VanDerWaalsContact C-ND1 3.35Å; D148-H150 PolarHBondContact O-N 3.28Å; D148-H150 PolarHBondContact O-ND1 3.35Å; H150-H152 PolarHBondContact O-N 2.86Å; H150-H153 HydrophobicContact CB-CB 3.6Å; H150-H153 AromaticContact CD2-CD2 3.76Å; H150-H153 WeakPolarHBondContact O-CB 3.35Å; H150-H153 PolarHBondContact O-N 2.98Å; H150-F244 AromaticContact NE2-CE1 3.83Å; H150-H247 AromaticContact CG-CD2 3.9Å
151C97.6Very high97.4Very high28 Ų2834.7 Ų34.719%0.18920%0.198CC..THydrogen-bonded Turntrans-63-16.6-172.373.50000115.1L142 C144 D149 V156L142-C151 PolarHBondContact O-N 3.29Å; C144-C151 WeakPolarHBondContact CA-SG 3.38Å; C144-C151 HydrophobicContact CB-CB 3.78Å; C144-C151 WeakPolarHBondContact CB-SG 3.46Å; C144-C151 PolarHBondContact N-SG 2.94Å; C144-C151 WeakPolarHBondContact SG-CB 3.25Å; C144-C151 CovalentContact SG-SG 2Å; C144-C151 PolarHBondContact SG-SG 3.23Å; D149-C151 PolarHBondContact O-N 2.86Å; D149-C151 VanDerWaalsContact O-N 3.08Å; D149-C151 PolarHBondContact OD1-N 3.32Å; C151-V156 WeakPolarHBondContact O-CG2 3.44Å
152H98.3Very high97.5Very high4 Ų434.2 Ų34.22%0.01919%0.193CC..THydrogen-bonded Turntrans-118.64.3178.2-62.2-52.1000112.2S111 G113 L114 W138 L142 C144 H150S111-H152 PolarHBondContact O-NE2 3.2Å; G113-H152 PolarHBondContact N-NE2 3.22Å; L114-H152 PolarHBondContact O-ND1 3.38Å; W138-H152 PolarHBondContact NE1-O 3Å; L142-H152 PolarHBondContact O-N 2.83Å; C144-H152 PolarHBondContact SG-NE2 3.38Å; C144-H152 VanDerWaalsContact SG-NE2 3.35Å; H150-H152 PolarHBondContact O-N 2.86Å
153H98.5Very high97.5Very high1 Ų134.5 Ų34.51%0.00519%0.194CC..SBendtrans-65.1149.2-177.4-175.6-93.8000111.4L142 H150 S155 V156 H157 F162 D246 H247L142-H153 HydrophobicContact CD1-CB 4.48Å; H150-H153 HydrophobicContact CB-CB 3.6Å; H150-H153 AromaticContact CD2-CD2 3.76Å; H150-H153 WeakPolarHBondContact O-CB 3.35Å; H150-H153 PolarHBondContact O-N 2.98Å; H153-S155 WeakPolarHBondContact ND1-CB 3.17Å; H153-S155 PolarHBondContact ND1-N 3.39Å; H153-S155 VanDerWaalsContact ND1-N 3.2Å; H153-S155 PolarHBondContact ND1-OG 3.3Å; H153-S155 PolarHBondContact O-N 3.38Å; H153-V156 WeakPolarHBondContact O-CG2 3.3Å; H153-V156 PolarHBondContact O-N 2.64Å; H153-H157 PolarHBondContact O-CD2 2.88Å; H153-F162 AromaticContact CE1-CD1 3.89Å; H153-F162 AromaticContact NE2-CD1 3.38Å; H153-F162 WeakPolarHBondContact NE2-CD1 3.28Å; H153-F162 AromaticContact NE2-CE1 3.92Å; H153-D246 PolarHBondContact CE1-O 3.04Å; H153-D246 PolarHBondContact NE2-O 3.4Å; H153-H247 AromaticContact ND1-CD2 3.93Å; H153-H247 AromaticContact ND1-NE2 3.76Å
154P98.7Very high97.5Very high0 Ų034.5 Ų34.50%019%0.194CC..G310 helixtrans-48.3-32.3178.7-31.535.9000115.1L134 W138 V156 H157 G158 F159 F162L134-P154 HydrophobicContact CD2-CB 3.79Å; L134-P154 HydrophobicContact CD2-CG 3.54Å; W138-P154 HydrophobicContact CB-CG 4.22Å; W138-P154 HydrophobicContact CD2-CG 3.71Å; W138-P154 HydrophobicContact CE3-CG 4.08Å; W138-P154 HydrophobicContact CG-CG 3.77Å; P154-V156 PolarHBondContact O-N 3.09Å; P154-H157 CarbonylContact O-C 3.53Å; P154-H157 WeakPolarHBondContact O-CA 3.38Å; P154-H157 PolarHBondContact O-N 3.17Å; P154-G158 PolarHBondContact O-N 3.05Å; P154-F159 HydrophobicContact CB-CB 4.17Å; P154-F159 HydrophobicContact CB-CD2 3.92Å; P154-F159 HydrophobicContact CB-CG 4.39Å; P154-F159 PolarHBondContact O-N 3.35Å; P154-F162 HydrophobicContact CB-CB 4.37Å; P154-F162 HydrophobicContact CB-CD2 4.37Å; P154-F162 HydrophobicContact CB-CG 4.27Å; P154-F162 HydrophobicContact CG-CD1 4.12Å; P154-F162 HydrophobicContact CG-CD2 3.92Å; P154-F162 HydrophobicContact CG-CE1 4.24Å; P154-F162 HydrophobicContact CG-CE2 4.08Å; P154-F162 HydrophobicContact CG-CG 3.94Å; P154-F162 HydrophobicContact CG-CZ 4.23Å
155S97.8Very high97.6Very high33 Ų3332.8 Ų32.823%0.23118%0.182CC..G310 helixtrans-60.5-38.4179.761.50000113.9H153 H157 G158 F159 H247H153-S155 WeakPolarHBondContact ND1-CB 3.17Å; H153-S155 PolarHBondContact ND1-N 3.39Å; H153-S155 VanDerWaalsContact ND1-N 3.2Å; H153-S155 PolarHBondContact ND1-OG 3.3Å; H153-S155 PolarHBondContact O-N 3.38Å; S155-H157 PolarHBondContact O-N 3.26Å; S155-G158 PolarHBondContact O-N 2.95Å; S155-F159 WeakPolarHBondContact CA-O 3.03Å; S155-H247 PolarHBondContact OG-NE2 3.29Å
156V98.1Very high97.6Very high52 Ų5225 Ų2532%0.31515%0.146SC..G310 helixtrans-76.8-14.1177-57.30000112.8K123 C151 H153 P154K123-V156 PolarHBondContact NZ-O 3.47Å; C151-V156 WeakPolarHBondContact O-CG2 3.44Å; H153-V156 WeakPolarHBondContact O-CG2 3.3Å; H153-V156 PolarHBondContact O-N 2.64Å; P154-V156 PolarHBondContact O-N 3.09Å
157H98.6Very high97.7Very high0 Ų023.1 Ų23.10%013%0.132CC..G310 helixtrans-100.919.7175.7-66.2-69.8000113.1L114 T120 W138 H153 P154 S155L114-H157 PolarHBondContact O-CE1 2.84Å; L114-H157 VanDerWaalsContact O-CE1 3.24Å; L114-H157 PolarHBondContact O-NE2 2.76Å; L114-H157 VanDerWaalsContact O-NE2 3.08Å; T120-H157 HydrophobicContact CG2-CB 3.99Å; T120-H157 PolarHBondContact OG1-O 3.43Å; W138-H157 HydrophobicContact CH2-CB 3.92Å; W138-H157 HydrophobicContact CZ2-CB 4.28Å; W138-H157 AromaticContact CZ2-CD2 3.5Å; H153-H157 PolarHBondContact O-CD2 2.88Å; P154-H157 CarbonylContact O-C 3.53Å; P154-H157 WeakPolarHBondContact O-CA 3.38Å; P154-H157 PolarHBondContact O-N 3.17Å; S155-H157 PolarHBondContact O-N 3.26Å
158G98.4Very high97.7Very high4 Ų420.9 Ų20.94%0.04112%0.116CC..THydrogen-bonded Turntrans91.810.5165.200000115.8K126 T132 P154 S155K126-G158 WeakPolarHBondContact CD-O 3.3Å; T132-G158 WeakPolarHBondContact CB-O 3.45Å; T132-G158 PolarHBondContact OG1-O 2.98Å; P154-G158 PolarHBondContact O-N 3.05Å; S155-G158 PolarHBondContact O-N 2.95Å
159F98.8Very high97.7Very high3 Ų315.5 Ų15.51%0.0139%0.087CC..  trans-89.2124.5170.3-64.7-76.1000110.8L86 A122 T132 A133 L134 W138 P154 S155 L280 F282L86-F159 HydrophobicContact CD2-CE2 4.38Å; L86-F159 HydrophobicContact CD2-CZ 4.16Å; A122-F159 HydrophobicContact CB-CD1 4.07Å; A122-F159 HydrophobicContact CB-CD2 4.23Å; A122-F159 HydrophobicContact CB-CE1 3.7Å; A122-F159 HydrophobicContact CB-CE2 3.85Å; A122-F159 HydrophobicContact CB-CG 4.34Å; A122-F159 HydrophobicContact CB-CZ 3.57Å; T132-F159 VanDerWaalsContact OG1-CA 3.23Å; T132-F159 WeakPolarHBondContact OG1-CA 3.17Å; A133-F159 VanDerWaalsContact C-CD1 3.44Å; L134-F159 HydrophobicContact CB-CB 4.37Å; L134-F159 HydrophobicContact CB-CD1 3.78Å; L134-F159 HydrophobicContact CB-CD2 4.15Å; L134-F159 HydrophobicContact CB-CE1 4.03Å; L134-F159 HydrophobicContact CB-CE2 4.39Å; L134-F159 HydrophobicContact CB-CG 3.83Å; L134-F159 HydrophobicContact CB-CZ 4.34Å; W138-F159 HydrophobicContact CZ3-CE2 4.06Å; P154-F159 HydrophobicContact CB-CB 4.17Å; P154-F159 HydrophobicContact CB-CD2 3.92Å; P154-F159 HydrophobicContact CB-CG 4.39Å; P154-F159 PolarHBondContact O-N 3.35Å; S155-F159 WeakPolarHBondContact CA-O 3.03Å; F159-L280 HydrophobicContact CE1-CD2 3.8Å; F159-F282 HydrophobicContact CE1-CB 3.91Å; F159-F282 HydrophobicContact CE1-CD1 4.5Å; F159-F282 HydrophobicContact CZ-CB 4.18Å; F159-F282 AromaticContact CZ-CD1 3.95Å; F159-F282 HydrophobicContact CZ-CD1 3.95Å
160D98.4Very high97.4Very high73 Ų7313.2 Ų13.239%0.398%0.075SC..SBendtrans-74.1-32.6175-65.9-50000112.3K126 T132K126-D160 WeakPolarHBondContact CD-OD1 3.42Å; K126-D160 WeakPolarHBondContact CE-OD1 3.47Å; K126-D160 IonicContact NZ-OD1 2.77Å; K126-D160 PolarHBondContact NZ-OD1 2.98Å; T132-D160 PolarHBondContact N-OD2 2.76Å; T132-D160 VanDerWaalsContact N-OD2 3.09Å; T132-D160 WeakPolarHBondContact O-CA 3.45Å; T132-D160 WeakPolarHBondContact O-CB 3.49Å; T132-D160 PolarHBondContact O-N 3.38Å; T132-D160 PolarHBondContact OG1-N 2.85Å; T132-D160 PolarHBondContact OG1-OD2 3.07Å
161Y98.8Very high97Very high24 Ų2413.6 Ų13.69%0.0948%0.076CC..EExtended strand (participates in β ladder)trans-127.6138.2-179-177.1-117.6000111.3T132 A133 L134 F163 R245 D246 E266T132-Y161 PolarHBondContact O-N 2.87Å; A133-Y161 WeakPolarHBondContact CA-O 3.36Å; A133-Y161 HydrophobicContact CB-CD1 4.09Å; L134-Y161 PolarHBondContact N-O 3.48Å; Y161-F163 HydrophobicContact CE1-CB 4.04Å; Y161-R245 HydrophobicContact CE2-CG 4.15Å; Y161-R245 PolarHBondContact OH-NH1 3.46Å; Y161-D246 VanDerWaalsContact CD2-OD1 3.28Å; Y161-D246 WeakPolarHBondContact CD2-OD1 2.96Å; Y161-E266 PolarHBondContact OH-OE2 3.23Å
162F98.8Very high96.7Very high2 Ų212.9 Ų12.91%0.0097%0.07CC..EExtended strand (participates in β ladder)trans-132.5128.5172.2176.4-129.1000111.3L134 W138 H153 P154 F244 R245 D246L134-F162 HydrophobicContact CB-CD2 4.01Å; L134-F162 HydrophobicContact CD2-CD2 3.74Å; L134-F162 HydrophobicContact CD2-CE2 3.73Å; L134-F162 HydrophobicContact CG-CD2 3.77Å; L134-F162 HydrophobicContact CG-CE2 3.95Å; L134-F162 WeakPolarHBondContact O-CA 3.36Å; L134-F162 WeakPolarHBondContact O-CD2 3.43Å; W138-F162 HydrophobicContact CB-CZ 4.44Å; H153-F162 AromaticContact CE1-CD1 3.89Å; H153-F162 AromaticContact NE2-CD1 3.38Å; H153-F162 WeakPolarHBondContact NE2-CD1 3.28Å; H153-F162 AromaticContact NE2-CE1 3.92Å; P154-F162 HydrophobicContact CB-CB 4.37Å; P154-F162 HydrophobicContact CB-CD2 4.37Å; P154-F162 HydrophobicContact CB-CG 4.27Å; P154-F162 HydrophobicContact CG-CD1 4.12Å; P154-F162 HydrophobicContact CG-CD2 3.92Å; P154-F162 HydrophobicContact CG-CE1 4.24Å; P154-F162 HydrophobicContact CG-CE2 4.08Å; P154-F162 HydrophobicContact CG-CG 3.94Å; P154-F162 HydrophobicContact CG-CZ 4.23Å; F162-F244 HydrophobicContact CD1-CB 3.95Å; F162-F244 HydrophobicContact CE1-CB 3.59Å; F162-F244 HydrophobicContact CE1-CG 4.33Å; F162-R245 CarbonylContact O-C 3.53Å; F162-R245 WeakPolarHBondContact O-CA 3.27Å; F162-D246 PolarHBondContact N-OD1 3.4Å; F162-D246 VanDerWaalsContact N-OD1 3.12Å; F162-D246 PolarHBondContact O-N 2.95Å
163F98.8Very high96.4Very high6 Ų613.3 Ų13.33%0.0267%0.073CC..EExtended strand (participates in β ladder)trans-133114.8165175.2-93.7000109.1L134 I135 G136 Y161 L243 F244 R245 K262 M263 E266L134-F163 PolarHBondContact O-N 3.33Å; I135-F163 CarbonylContact C-O 3.6Å; I135-F163 VanDerWaalsContact CA-O 3.26Å; I135-F163 WeakPolarHBondContact CA-O 3.43Å; I135-F163 HydrophobicContact CG2-CD1 4.26Å; G136-F163 PolarHBondContact N-O 3.27Å; Y161-F163 HydrophobicContact CE1-CB 4.04Å; F163-L243 HydrophobicContact CE1-CD1 4.43Å; F163-L243 HydrophobicContact CE2-CD2 4.13Å; F163-L243 HydrophobicContact CE2-CG 4.4Å; F163-L243 HydrophobicContact CZ-CD1 4.22Å; F163-L243 HydrophobicContact CZ-CD2 3.93Å; F163-L243 HydrophobicContact CZ-CG 4.41Å; F163-F244 WeakPolarHBondContact CA-O 3.48Å; F163-R245 HydrophobicContact CD2-CB 4.4Å; F163-K262 HydrophobicContact CE1-CB 4.23Å; F163-K262 HydrophobicContact CZ-CB 4.18Å; F163-M263 HydrophobicContact CD1-CG 4.41Å; F163-M263 HydrophobicContact CE1-CG 4.15Å; F163-E266 HydrophobicContact CB-CG 4.32Å; F163-E266 HydrophobicContact CD1-CB 4.16Å; F163-E266 HydrophobicContact CD1-CG 3.65Å; F163-E266 HydrophobicContact CD2-CG 4.18Å; F163-E266 HydrophobicContact CE1-CG 3.92Å; F163-E266 HydrophobicContact CE2-CG 4.42Å; F163-E266 HydrophobicContact CG-CB 4.41Å; F163-E266 HydrophobicContact CG-CG 3.78Å; F163-E266 HydrophobicContact CZ-CG 4.29Å
164G98.1Very high95.9Very high1 Ų115.3 Ų15.31%0.018%0.082CC..EExtended strand (participates in β ladder)trans155.5-154.3-178.700000114.3G136 F244G136-G164 CarbonylContact O-C 3.43Å; G136-G164 VanDerWaalsContact O-CA 3.28Å; G136-G164 WeakPolarHBondContact O-CA 3.36Å; G164-F244 PolarHBondContact N-O 3.36Å; G164-F244 PolarHBondContact O-N 3.03Å
165I98.1Very high95.1Very high3 Ų321.2 Ų21.22%0.01512%0.121CC..EExtended strand (participates in β ladder)trans-114132.4-171.267.7172.1000110.8G136 K137 W138 L167 T168 I242 L243 F254 L286G136-I165 PolarHBondContact O-N 3.26Å; K137-I165 HydrophobicContact CB-CG1 4.32Å; W138-I165 PolarHBondContact N-O 3.27Å; I165-L167 VanDerWaalsContact C-N 3.35Å; I165-L167 PolarHBondContact O-N 2.86Å; I165-T168 VanDerWaalsContact CD1-C 3.41Å; I165-I242 WeakPolarHBondContact CG2-O 3.36Å; I165-L243 HydrophobicContact CG2-CD1 4.14Å; I165-F254 HydrophobicContact CB-CE1 4.42Å; I165-F254 HydrophobicContact CG2-CD1 3.8Å; I165-F254 HydrophobicContact CG2-CE1 3.57Å; I165-F254 HydrophobicContact CG2-CZ 4.37Å; I165-L286 HydrophobicContact CD1-CD1 4.04Å; I165-L286 HydrophobicContact CD1-CD2 3.78Å; I165-L286 HydrophobicContact CD1-CG 3.69Å; I165-L286 HydrophobicContact CG1-CD1 4.05Å; I165-L286 HydrophobicContact CG1-CD2 4.44Å; I165-L286 HydrophobicContact CG1-CG 4.26Å; I165-L286 HydrophobicContact CG2-CD2 4.47Å
166P97.1Very high94.4Very high2 Ų223.1 Ų23.11%0.01315%0.145CC..SBendtrans-72.3-26.6-179.123.9-30.2000113.6N108 H139 L142 I242 F244N108-P166 WeakPolarHBondContact OD1-CG 3.18Å; H139-P166 WeakPolarHBondContact CA-O 3.29Å; H139-P166 PolarHBondContact N-O 3.34Å; L142-P166 HydrophobicContact CB-CB 4.39Å; L142-P166 HydrophobicContact CD1-CB 4.05Å; L142-P166 HydrophobicContact CD2-CB 4.46Å; L142-P166 HydrophobicContact CD2-CG 4.32Å; P166-I242 WeakPolarHBondContact CD-O 3.44Å; P166-F244 HydrophobicContact CG-CD2 3.87Å; P166-F244 HydrophobicContact CG-CE2 3.79Å
167L96.4Very high93.5Very high6 Ų623.3 Ų23.33%0.03114%0.143CC..SBendtrans-97.8-119.6179.8-168.468.5000111.5F105 N108 H139 I165 L170 N240F105-L167 HydrophobicContact CB-CD1 3.8Å; F105-L167 WeakPolarHBondContact O-CD1 3.42Å; N108-L167 VanDerWaalsContact OD1-CB 3.26Å; N108-L167 WeakPolarHBondContact OD1-CB 3.45Å; H139-L167 VanDerWaalsContact CA-O 3.24Å; H139-L167 WeakPolarHBondContact CA-O 3.19Å; H139-L167 WeakPolarHBondContact CB-O 3.32Å; H139-L167 PolarHBondContact N-O 2.68Å; I165-L167 VanDerWaalsContact C-N 3.35Å; I165-L167 PolarHBondContact O-N 2.86Å; L167-L170 HydrophobicContact CD2-CD1 3.96Å; L167-N240 HydrophobicContact CD2-CB 4.07Å
168T95.6Very high92.8Very high5 Ų525.6 Ų25.63%0.03117%0.167CC..  trans-146.3157.7-179.9-172.30000108.2K137 I165 L170K137-T168 WeakPolarHBondContact CE-OG1 3.49Å; K137-T168 PolarHBondContact NZ-OG1 2.98Å; I165-T168 VanDerWaalsContact CD1-C 3.41Å; T168-L170 HydrophobicContact CG2-CD2 3.58Å; T168-L170 HydrophobicContact CG2-CG 4.05Å; T168-L170 PolarHBondContact O-N 3.09Å
169N93.6Very high92Very high0 Ų026.3 Ų26.30%017%0.17CC..  trans-63131.4166.1-17121000108L286 H289 T290 A291N169-L286 HydrophobicContact CB-CB 4.45Å; N169-L286 HydrophobicContact CB-CD2 4.46Å; N169-L286 HydrophobicContact CB-CG 4.41Å; N169-H289 PolarHBondContact ND2-O 3.16Å; N169-H289 PolarHBondContact O-CE1 3.19Å; N169-H289 PolarHBondContact O-ND1 2.85Å; N169-T290 CarbonylContact C-O 3.54Å; N169-T290 VanDerWaalsContact C-O 3.25Å; N169-A291 PolarHBondContact ND2-N 2.95Å; N169-A291 PolarHBondContact ND2-O 3.14Å
170L90.3Very high91.3Very high7 Ų728.7 Ų28.74%0.03719%0.185CC..  trans-121.3154.1179.1-65.9174.1000108.5L167 T168 D172 C173 V180 N240L167-L170 HydrophobicContact CD2-CD1 3.96Å; T168-L170 HydrophobicContact CG2-CD2 3.58Å; T168-L170 HydrophobicContact CG2-CG 4.05Å; T168-L170 PolarHBondContact O-N 3.09Å; L170-D172 HydrophobicContact CB-CB 4.45Å; L170-D172 PolarHBondContact O-N 3.41Å; L170-D172 VanDerWaalsContact O-N 3.16Å; L170-C173 WeakPolarHBondContact O-CB 3.36Å; L170-C173 PolarHBondContact O-N 2.78Å; L170-V180 HydrophobicContact CB-CG2 4.23Å; L170-V180 HydrophobicContact CD2-CG2 4Å; L170-N240 HydrophobicContact CD1-CB 4.27Å
171R88.8Confident90.5Very high32 Ų3226.3 Ų26.312%0.12117%0.171CC..G310 helixtrans-51.4-38.6170.6-74.1178.7171.5-1502.5112.1C173 Q174 H177 G178 V180 T290 E348 L349R171-C173 PolarHBondContact O-N 2.77Å; R171-Q174 PolarHBondContact O-N 2.82Å; R171-Q174 VanDerWaalsContact O-N 3.16Å; R171-Q174 VanDerWaalsContact O-O 3.12Å; R171-H177 HydrophobicContact CB-CB 4.33Å; R171-H177 WeakPolarHBondContact CD-O 3.32Å; R171-G178 CarbonylContact C-O 3.59Å; R171-V180 HydrophobicContact CB-CG2 3.93Å; R171-V180 HydrophobicContact CG-CG2 4.25Å; R171-T290 HydrophobicContact CG-CG2 3.96Å; R171-T290 VanDerWaalsContact CG-OG1 3.32Å; R171-T290 WeakPolarHBondContact CG-OG1 3.08Å; R171-E348 IonicContact CZ-OE1 3.28Å; R171-E348 IonicContact CZ-OE2 3.89Å; R171-E348 IonicContact NE-OE1 2.72Å; R171-E348 PolarHBondContact NE-OE1 2.94Å; R171-E348 IonicContact NE-OE2 3.14Å; R171-E348 PolarHBondContact NE-OE2 3.22Å; R171-E348 IonicContact NH2-OE1 2.75Å; R171-E348 PolarHBondContact NH2-OE1 2.94Å; R171-E348 IonicContact NH2-OE2 3.98Å; R171-E348 PolarHBondContact NH2-OE2 3.35Å; R171-L349 PolarHBondContact NH2-O 3.23Å
172D90.9Very high89.4Confident13 Ų1327.7 Ų27.77%0.0718%0.178CC..G310 helixtrans-60.3-25.9178.7-55.7-107000112.9L170 Q174 T179 V180 I236 P237L170-D172 HydrophobicContact CB-CB 4.45Å; L170-D172 PolarHBondContact O-N 3.41Å; L170-D172 VanDerWaalsContact O-N 3.16Å; D172-Q174 PolarHBondContact O-N 2.8Å; D172-T179 WeakPolarHBondContact OD1-CA 3.49Å; D172-T179 WeakPolarHBondContact OD1-CB 3.46Å; D172-T179 PolarHBondContact OD1-OG1 2.98Å; D172-T179 WeakPolarHBondContact OD2-CA 3.45Å; D172-V180 PolarHBondContact OD2-N 3.36Å; D172-I236 HydrophobicContact CB-CB 4.44Å; D172-I236 HydrophobicContact CB-CG2 3.51Å; D172-P237 VanDerWaalsContact O-CG 3.25Å; D172-P237 WeakPolarHBondContact O-CG 3.34Å
173C91.2Very high88.3Confident12 Ų1230 Ų308%0.08119%0.19CC..G310 helixtrans-75.3-9179.8-59.20000114L170 R171 C241 F254L170-C173 WeakPolarHBondContact O-CB 3.36Å; L170-C173 PolarHBondContact O-N 2.78Å; R171-C173 PolarHBondContact O-N 2.77Å; C173-C241 WeakPolarHBondContact CA-SG 3.32Å; C173-C241 HydrophobicContact CB-CB 3.78Å; C173-C241 WeakPolarHBondContact CB-SG 3.29Å; C173-C241 WeakPolarHBondContact SG-CB 3.25Å; C173-C241 CovalentContact SG-SG 2.03Å; C173-C241 PolarHBondContact SG-SG 2.96Å; C173-F254 HydrophobicContact CB-CE2 3.81Å; C173-F254 HydrophobicContact CB-CZ 3.79Å
174Q87.8Confident86.8Confident43 Ų4334.2 Ų34.220%0.20121%0.21CC..SBendtrans-124.1116.6176.2-163.4163-29.900110.8R171 D172 G176 H177 L256 A291 L292R171-Q174 PolarHBondContact O-N 2.82Å; R171-Q174 VanDerWaalsContact O-N 3.16Å; R171-Q174 VanDerWaalsContact O-O 3.12Å; D172-Q174 PolarHBondContact O-N 2.8Å; Q174-G176 PolarHBondContact O-N 3.01Å; Q174-H177 HydrophobicContact CB-CB 4.31Å; Q174-H177 VanDerWaalsContact CG-CD2 3.48Å; Q174-H177 WeakPolarHBondContact CG-CD2 3.19Å; Q174-H177 PolarHBondContact NE2-CE1 3Å; Q174-H177 PolarHBondContact NE2-NE2 3.49Å; Q174-H177 PolarHBondContact O-N 3.33Å; Q174-L256 HydrophobicContact CB-CD1 3.87Å; Q174-L256 HydrophobicContact CG-CD1 4.23Å; Q174-A291 HydrophobicContact CB-CB 3.31Å; Q174-A291 HydrophobicContact CG-CB 4.21Å; Q174-L292 PolarHBondContact NE2-O 3.48Å; Q174-L292 PolarHBondContact OE1-O 3.16Å
175P83.4Confident85.4Confident125 Ų12539.5 Ų39.581%0.81223%0.232SC*.THydrogen-bonded Turntrans-52.6131175.7-27.135.1000111.8
176G81.6Confident84.1Confident72 Ų7246.8 Ų46.874%0.74226%0.261SS*.THydrogen-bonded Turntrans91.9-8.3178.800000115.9Q174Q174-G176 PolarHBondContact O-N 3.01Å
177H80.4Confident83Confident56 Ų5649 Ų4926%0.25927%0.272SS..SBendtrans-89.4-2.3179.8-73.9-115.2000114R171 Q174 A291R171-H177 HydrophobicContact CB-CB 4.33Å; R171-H177 WeakPolarHBondContact CD-O 3.32Å; Q174-H177 HydrophobicContact CB-CB 4.31Å; Q174-H177 VanDerWaalsContact CG-CD2 3.48Å; Q174-H177 WeakPolarHBondContact CG-CD2 3.19Å; Q174-H177 PolarHBondContact NE2-CE1 3Å; Q174-H177 PolarHBondContact NE2-NE2 3.49Å; Q174-H177 PolarHBondContact O-N 3.33Å; H177-A291 HydrophobicContact CB-CB 3.97Å
178G83.1Confident82.1Confident49 Ų4952 Ų5251%0.50529%0.292SS..  trans86.3-159.6179.500000112.6R171R171-G178 CarbonylContact C-O 3.59Å
179T82.1Confident81.2Confident18 Ų1855.1 Ų55.111%0.1130%0.304CS..  trans-127.3141.6-178.3-178.10000110.8D172 F181 Q182 I233D172-T179 WeakPolarHBondContact OD1-CA 3.49Å; D172-T179 WeakPolarHBondContact OD1-CB 3.46Å; D172-T179 PolarHBondContact OD1-OG1 2.98Å; D172-T179 WeakPolarHBondContact OD2-CA 3.45Å; T179-F181 WeakPolarHBondContact CG2-O 3.37Å; T179-F181 WeakPolarHBondContact OG1-CB 3.12Å; T179-F181 PolarHBondContact OG1-N 3.02Å; T179-Q182 PolarHBondContact O-NE2 3.37Å; T179-I233 HydrophobicContact CG2-CD1 4.31Å; T179-I233 HydrophobicContact CG2-CG2 4.29Å
180V83.1Confident80.4Confident53 Ų5358 Ų5832%0.32133%0.334SS..SBendtrans-72.8-21.1169.8-170.20000110.3L170 R171 D172 Q182L170-V180 HydrophobicContact CB-CG2 4.23Å; L170-V180 HydrophobicContact CD2-CG2 4Å; R171-V180 HydrophobicContact CB-CG2 3.93Å; R171-V180 HydrophobicContact CG-CG2 4.25Å; D172-V180 PolarHBondContact OD2-N 3.36Å; V180-Q182 PolarHBondContact O-N 2.84Å; V180-Q182 VanDerWaalsContact O-N 3.07Å
181F82.8Confident80Confident23 Ų2361.8 Ų61.810%0.10136%0.361CS..  trans-82.186.3179-60.3-84.2000111.6I106 F107 T179 I183 F232 I236I106-F181 HydrophobicContact CB-CZ 4.45Å; I106-F181 HydrophobicContact CD1-CE1 3.75Å; I106-F181 HydrophobicContact CD1-CZ 4.39Å; I106-F181 HydrophobicContact CG1-CE1 4.29Å; F107-F181 HydrophobicContact CD1-CZ 4.43Å; F107-F181 AromaticContact CE1-CE1 3.86Å; F107-F181 HydrophobicContact CE1-CE1 3.86Å; F107-F181 AromaticContact CE1-CZ 3.68Å; F107-F181 HydrophobicContact CE1-CZ 3.68Å; F107-F181 HydrophobicContact CE2-CE1 4.03Å; F107-F181 HydrophobicContact CE2-CZ 4.46Å; F107-F181 HydrophobicContact CZ-CD1 4.4Å; F107-F181 AromaticContact CZ-CE1 3.37Å; F107-F181 HydrophobicContact CZ-CE1 3.37Å; F107-F181 AromaticContact CZ-CZ 3.7Å; F107-F181 HydrophobicContact CZ-CZ 3.7Å; T179-F181 WeakPolarHBondContact CG2-O 3.37Å; T179-F181 WeakPolarHBondContact OG1-CB 3.12Å; T179-F181 PolarHBondContact OG1-N 3.02Å; F181-I183 HydrophobicContact CB-CD1 4.31Å; F181-I183 HydrophobicContact CB-CG1 4.27Å; F181-I183 PolarHBondContact O-N 3.34Å; F181-F232 HydrophobicContact CD1-CE1 4.41Å; F181-I236 HydrophobicContact CD2-CD1 4.19Å; F181-I236 HydrophobicContact CD2-CG1 3.98Å; F181-I236 HydrophobicContact CD2-CG2 4.38Å; F181-I236 HydrophobicContact CE2-CD1 3.67Å; F181-I236 HydrophobicContact CE2-CG1 3.85Å; F181-I236 HydrophobicContact CE2-CG2 3.83Å; F181-I236 HydrophobicContact CZ-CD1 3.96Å
182Q74.8Confident79.5Confident53 Ų5363.6 Ų63.625%0.24837%0.372CS..  trans-75.739.3-179.9-60.2-70.1-45.600113.6T179 V180 H184 K185 Y186T179-Q182 PolarHBondContact O-NE2 3.37Å; V180-Q182 PolarHBondContact O-N 2.84Å; V180-Q182 VanDerWaalsContact O-N 3.07Å; Q182-H184 PolarHBondContact O-N 2.94Å; Q182-H184 VanDerWaalsContact O-N 3.15Å; Q182-H184 PolarHBondContact OE1-CE1 3.48Å; Q182-K185 HydrophobicContact CB-CD 4.19Å; Q182-K185 HydrophobicContact CB-CG 4.34Å; Q182-K185 WeakPolarHBondContact O-CB 3.42Å; Q182-K185 PolarHBondContact O-N 2.93Å; Q182-Y186 WeakPolarHBondContact O-CD2 3.35Å
183I75.6Confident79Confident51 Ų5164.7 Ų64.726%0.26239%0.387SS..Hα-helixtrans-56.7-35.6-174.8-60.6172000111.6F181 K185 Y186 L187 V229 F232F181-I183 HydrophobicContact CB-CD1 4.31Å; F181-I183 HydrophobicContact CB-CG1 4.27Å; F181-I183 PolarHBondContact O-N 3.34Å; I183-K185 PolarHBondContact O-N 2.85Å; I183-Y186 PolarHBondContact O-N 2.93Å; I183-L187 HydrophobicContact CG2-CD1 4Å; I183-L187 HydrophobicContact CG2-CG 4.48Å; I183-L187 PolarHBondContact O-N 2.68Å; I183-V229 HydrophobicContact CB-CG1 4.18Å; I183-V229 HydrophobicContact CD1-CG1 4.39Å; I183-V229 HydrophobicContact CG2-CG1 3.98Å; I183-V229 HydrophobicContact CG2-CG2 4.14Å; I183-F232 HydrophobicContact CD1-CD1 4.09Å; I183-F232 HydrophobicContact CD1-CE1 4.26Å
184H67.8Low78.7Confident94 Ų9466.6 Ų66.644%0.43540%0.403SS..Hα-helixtrans-61.2-26.9179.566.9-86.1000113.7Q182 Y186 L187 Y189Q182-H184 PolarHBondContact O-N 2.94Å; Q182-H184 VanDerWaalsContact O-N 3.15Å; Q182-H184 PolarHBondContact OE1-CE1 3.48Å; H184-Y186 VanDerWaalsContact C-N 3.27Å; H184-Y186 PolarHBondContact O-N 3.5Å; H184-L187 PolarHBondContact O-N 2.78Å; H184-Y189 HydrophobicContact CB-CE2 4.42Å
185K69.1Low78.4Confident112 Ų11267.4 Ų67.449%0.48742%0.417SS..Hα-helixtrans-68.4-27.8175.5-69.7-170.6176-178.10112.5Q182 I183 H482Q182-K185 HydrophobicContact CB-CD 4.19Å; Q182-K185 HydrophobicContact CB-CG 4.34Å; Q182-K185 WeakPolarHBondContact O-CB 3.42Å; Q182-K185 PolarHBondContact O-N 2.93Å; I183-K185 PolarHBondContact O-N 2.85Å; K185-H482 PolarHBondContact NZ-O 2.6Å
186Y70.9Confident78.3Confident156 Ų15663.9 Ų63.961%0.61239%0.391SS*.Hα-helixtrans-91.8-14-178.4-59.1-72.4000113Q182 I183 H184Q182-Y186 WeakPolarHBondContact O-CD2 3.35Å; I183-Y186 PolarHBondContact O-N 2.93Å; H184-Y186 VanDerWaalsContact C-N 3.27Å; H184-Y186 PolarHBondContact O-N 3.5Å
187L73.7Confident78.4Confident48 Ų4866.2 Ų66.225%0.25139%0.386SS..SBendtrans-89.1121.5175.5-72.4169.6000109.2I183 H184 Y189 V225 V229I183-L187 HydrophobicContact CG2-CD1 4Å; I183-L187 HydrophobicContact CG2-CG 4.48Å; I183-L187 PolarHBondContact O-N 2.68Å; H184-L187 PolarHBondContact O-N 2.78Å; L187-Y189 HydrophobicContact CB-CD2 3.7Å; L187-Y189 HydrophobicContact CB-CE1 4.46Å; L187-Y189 HydrophobicContact CB-CE2 3.41Å; L187-Y189 VanDerWaalsContact CB-CE2 3.41Å; L187-Y189 HydrophobicContact CB-CG 4.37Å; L187-Y189 HydrophobicContact CD1-CE2 3.75Å; L187-Y189 VanDerWaalsContact CD1-OH 3.24Å; L187-Y189 WeakPolarHBondContact CD1-OH 3.48Å; L187-Y189 HydrophobicContact CG-CE2 4.22Å; L187-Y189 PolarHBondContact O-N 3.24Å; L187-V225 HydrophobicContact CD1-CG1 4.4Å; L187-V225 HydrophobicContact CD2-CG1 4.48Å; L187-V229 HydrophobicContact CD1-CG2 4.15Å
188P77.6Confident78.6Confident69 Ų6966.6 Ų66.645%0.44840%0.395SS..  trans-79.853-173.533.8-36.2000111.1G190 S191 L192P188-G190 PolarHBondContact O-N 3.43Å; P188-S191 PolarHBondContact O-N 3.04Å; P188-S191 VanDerWaalsContact O-N 3.12Å; P188-L192 HydrophobicContact CG-CD1 3.84Å; P188-L192 HydrophobicContact CG-CG 4.22Å; P188-L192 VanDerWaalsContact O-CB 3.32Å; P188-L192 WeakPolarHBondContact O-CB 2.91Å; P188-L192 WeakPolarHBondContact O-CG 3.45Å; P188-L192 PolarHBondContact O-N 3.36Å
189Y76.9Confident78.6Confident72 Ų7265.6 Ų65.628%0.28238%0.382SS..Hα-helixtrans-54.7-39.4-176.6-71.3-64.4000112.2H184 L187 G193 L222 T226H184-Y189 HydrophobicContact CB-CE2 4.42Å; L187-Y189 HydrophobicContact CB-CD2 3.7Å; L187-Y189 HydrophobicContact CB-CE1 4.46Å; L187-Y189 HydrophobicContact CB-CE2 3.41Å; L187-Y189 VanDerWaalsContact CB-CE2 3.41Å; L187-Y189 HydrophobicContact CB-CG 4.37Å; L187-Y189 HydrophobicContact CD1-CE2 3.75Å; L187-Y189 VanDerWaalsContact CD1-OH 3.24Å; L187-Y189 WeakPolarHBondContact CD1-OH 3.48Å; L187-Y189 HydrophobicContact CG-CE2 4.22Å; L187-Y189 PolarHBondContact O-N 3.24Å; Y189-G193 PolarHBondContact O-N 2.93Å; Y189-L222 HydrophobicContact CD1-CD1 4Å; Y189-L222 HydrophobicContact CE1-CD1 3.86Å; Y189-T226 WeakPolarHBondContact CE1-OG1 3.32Å; Y189-T226 PolarHBondContact OH-OG1 3.44Å
190G76.1Confident78.5Confident61 Ų6167.2 Ų67.263%0.62940%0.397SS*.Hα-helixtrans-64-49.517600000112.6P188 G193 A194P188-G190 PolarHBondContact O-N 3.43Å; G190-G193 PolarHBondContact O-N 2.86Å; G190-A194 WeakPolarHBondContact O-CB 2.88Å; G190-A194 PolarHBondContact O-N 3.08Å
191S81.5Confident78.6Confident85 Ų8568.6 Ų68.659%0.59441%0.406SS*.Hα-helixtrans-66.6-39.4178.2-47.80000112.1P188 A194 A195P188-S191 PolarHBondContact O-N 3.04Å; P188-S191 VanDerWaalsContact O-N 3.12Å; S191-A194 PolarHBondContact O-N 2.99Å; S191-A195 VanDerWaalsContact O-CB 3.22Å; S191-A195 WeakPolarHBondContact O-CB 3.48Å; S191-A195 PolarHBondContact O-N 3.39Å
192L80Confident78.7Confident71 Ų7170.9 Ų70.937%0.37242%0.418SS..Hα-helixtrans-62.6-45.7173.8-79.9159.6000111P188 A195 L196 L222P188-L192 HydrophobicContact CG-CD1 3.84Å; P188-L192 HydrophobicContact CG-CG 4.22Å; P188-L192 VanDerWaalsContact O-CB 3.32Å; P188-L192 WeakPolarHBondContact O-CB 2.91Å; P188-L192 WeakPolarHBondContact O-CG 3.45Å; P188-L192 PolarHBondContact O-N 3.36Å; L192-A195 PolarHBondContact O-N 3.24Å; L192-L196 WeakPolarHBondContact O-CB 3.46Å; L192-L196 VanDerWaalsContact O-CG 3.23Å; L192-L196 WeakPolarHBondContact O-CG 3.4Å; L192-L196 PolarHBondContact O-N 3Å; L192-L222 HydrophobicContact CD1-CD1 4.26Å
193G79.8Confident79.1Confident36 Ų3671.9 Ų71.937%0.37142%0.423SS..Hα-helixtrans-62-46.8176.500000112.1Y189 G190 L196 L197Y189-G193 PolarHBondContact O-N 2.93Å; G190-G193 PolarHBondContact O-N 2.86Å; G193-L196 PolarHBondContact O-N 3.46Å; G193-L197 WeakPolarHBondContact O-CB 3.34Å; G193-L197 PolarHBondContact O-N 3.02Å
194A83.8Confident79.5Confident52 Ų5280.5 Ų80.543%0.4345%0.452SS..Hα-helixtrans-63.5-41.2176.300000112.5G190 S191 L197 S198G190-A194 WeakPolarHBondContact O-CB 2.88Å; G190-A194 PolarHBondContact O-N 3.08Å; S191-A194 PolarHBondContact O-N 2.99Å; A194-L197 PolarHBondContact O-N 2.81Å; A194-S198 VanDerWaalsContact O-CB 3.28Å; A194-S198 WeakPolarHBondContact O-CB 3.42Å; A194-S198 PolarHBondContact O-N 2.99Å; A194-S198 PolarHBondContact O-OG 2.81Å
195A83.4Confident80.4Confident59 Ų5979.1 Ų79.149%0.48845%0.453SS..Hα-helixtrans-63.6-44.7175.200000111.5S191 L192 S198 A199S191-A195 VanDerWaalsContact O-CB 3.22Å; S191-A195 WeakPolarHBondContact O-CB 3.48Å; S191-A195 PolarHBondContact O-N 3.39Å; L192-A195 PolarHBondContact O-N 3.24Å; A195-S198 PolarHBondContact O-N 3.31Å; A195-A199 WeakPolarHBondContact O-CB 3.46Å; A195-A199 PolarHBondContact O-N 2.9Å
196L81.3Confident81.1Confident51 Ų5176.8 Ų76.827%0.26746%0.461SS..Hα-helixtrans-63.2-43.2176.4-74.1170.2000111.9L192 G193 A200 L219 L222L192-L196 WeakPolarHBondContact O-CB 3.46Å; L192-L196 VanDerWaalsContact O-CG 3.23Å; L192-L196 WeakPolarHBondContact O-CG 3.4Å; L192-L196 PolarHBondContact O-N 3Å; G193-L196 PolarHBondContact O-N 3.46Å; L196-A200 WeakPolarHBondContact O-CB 3.44Å; L196-A200 PolarHBondContact O-N 3.24Å; L196-L219 HydrophobicContact CD1-CD2 4.05Å; L196-L222 HydrophobicContact CD1-CD2 4.2Å
197L83.1Confident81.8Confident122 Ų12275.5 Ų75.564%0.63946%0.464SS*.Hα-helixtrans-62.9-47.2176.1-168.587.9000111.1G193 A194 A199 A200 V201G193-L197 WeakPolarHBondContact O-CB 3.34Å; G193-L197 PolarHBondContact O-N 3.02Å; A194-L197 PolarHBondContact O-N 2.81Å; L197-A199 PolarHBondContact O-N 3.34Å; L197-A200 WeakPolarHBondContact O-CB 3.18Å; L197-A200 PolarHBondContact O-N 2.79Å; L197-V201 WeakPolarHBondContact O-CG2 3.49Å; L197-V201 PolarHBondContact O-N 3.48Å
198S84.8Confident82.3Confident64 Ų6476.3 Ų76.345%0.44847%0.468SS..Hα-helixtrans-63-43.8179.6-57.20000111.1A194 A195 A200 V201 L202A194-S198 VanDerWaalsContact O-CB 3.28Å; A194-S198 WeakPolarHBondContact O-CB 3.42Å; A194-S198 PolarHBondContact O-N 2.99Å; A194-S198 PolarHBondContact O-OG 2.81Å; A195-S198 PolarHBondContact O-N 3.31Å; S198-A200 VanDerWaalsContact C-N 3.33Å; S198-A200 PolarHBondContact O-N 3.47Å; S198-V201 PolarHBondContact O-N 3.48Å; S198-L202 WeakPolarHBondContact O-CB 3.34Å; S198-L202 VanDerWaalsContact O-CG 3.26Å; S198-L202 WeakPolarHBondContact O-CG 3.39Å; S198-L202 PolarHBondContact O-N 3.04Å
199A81.8Confident82.5Confident27 Ų2781.2 Ų81.222%0.22349%0.49CS..Hα-helixtrans-61.5-40.5175.100000111.8A195 L197 H203 L210A195-A199 WeakPolarHBondContact O-CB 3.46Å; A195-A199 PolarHBondContact O-N 2.9Å; L197-A199 PolarHBondContact O-N 3.34Å; A199-H203 VanDerWaalsContact O-CB 3.29Å; A199-H203 WeakPolarHBondContact O-CB 3.25Å; A199-H203 PolarHBondContact O-N 3.06Å; A199-L210 HydrophobicContact CB-CD1 3.77Å; A199-L210 VanDerWaalsContact O-CD1 3.28Å; A199-L210 WeakPolarHBondContact O-CD1 3.28Å
200A81.3Confident82.6Confident52 Ų5279.6 Ų79.643%0.4349%0.486SS..Hα-helixtrans-65.1-42.8175.500000112.5L196 L197 S198 H203 W204L196-A200 WeakPolarHBondContact O-CB 3.44Å; L196-A200 PolarHBondContact O-N 3.24Å; L197-A200 WeakPolarHBondContact O-CB 3.18Å; L197-A200 PolarHBondContact O-N 2.79Å; S198-A200 VanDerWaalsContact C-N 3.33Å; S198-A200 PolarHBondContact O-N 3.47Å; A200-H203 PolarHBondContact O-N 3.08Å; A200-W204 WeakPolarHBondContact O-CB 3.14Å; A200-W204 PolarHBondContact O-N 2.93Å
201V84.6Confident83Confident83 Ų8385 Ų8550%0.50349%0.487SS..Hα-helixtrans-64.2-46.6176.7171.40000111.2L197 S198 H203 W204 S205L197-V201 WeakPolarHBondContact O-CG2 3.49Å; L197-V201 PolarHBondContact O-N 3.48Å; S198-V201 PolarHBondContact O-N 3.48Å; V201-H203 VanDerWaalsContact C-N 3.25Å; V201-H203 PolarHBondContact O-N 3.07Å; V201-W204 PolarHBondContact O-N 2.86Å; V201-S205 WeakPolarHBondContact O-CB 3.25Å; V201-S205 PolarHBondContact O-N 3.5Å; V201-S205 PolarHBondContact O-OG 3.08Å
202L85.1Confident82.9Confident70 Ų7090.5 Ų90.537%0.36650%0.495SS..Hα-helixtrans-63.6-32.4176.9-69.2173.1000112.3S198 S205 G206 L207 I208S198-L202 WeakPolarHBondContact O-CB 3.34Å; S198-L202 VanDerWaalsContact O-CG 3.26Å; S198-L202 WeakPolarHBondContact O-CG 3.39Å; S198-L202 PolarHBondContact O-N 3.04Å; L202-S205 WeakPolarHBondContact CA-OG 3.24Å; L202-S205 PolarHBondContact O-OG 3.44Å; L202-S205 VanDerWaalsContact O-OG 3.13Å; L202-G206 PolarHBondContact O-N 2.85Å; L202-L207 HydrophobicContact CD2-CB 4.3Å; L202-L207 HydrophobicContact CD2-CD1 3.67Å; L202-L207 PolarHBondContact O-N 3.24Å; L202-I208 HydrophobicContact CB-CD1 3.62Å; L202-I208 HydrophobicContact CB-CG1 3.7Å; L202-I208 HydrophobicContact CD1-CD1 4.29Å; L202-I208 PolarHBondContact O-N 2.01Å
203H83.3Confident83Confident75 Ų7596.3 Ų96.335%0.34751%0.512SS..Hα-helixtrans-70.9-42.4174.1-176.750.2000112.1A199 A200 V201 G206 I208 L210A199-H203 VanDerWaalsContact O-CB 3.29Å; A199-H203 WeakPolarHBondContact O-CB 3.25Å; A199-H203 PolarHBondContact O-N 3.06Å; A200-H203 PolarHBondContact O-N 3.08Å; V201-H203 VanDerWaalsContact C-N 3.25Å; V201-H203 PolarHBondContact O-N 3.07Å; H203-G206 PolarHBondContact O-N 3.26Å; H203-I208 WeakPolarHBondContact CA-O 3.31Å; H203-I208 HydrophobicContact CB-CG1 4.26Å; H203-I208 PolarHBondContact ND1-O 3.02Å; H203-L210 HydrophobicContact CB-CB 4.34Å; H203-L210 HydrophobicContact CB-CD1 3.91Å; H203-L210 HydrophobicContact CB-CG 4.23Å; H203-L210 PolarHBondContact CE1-N 2.98Å; H203-L210 PolarHBondContact ND1-N 3.01Å; H203-L210 VanDerWaalsContact ND1-N 3.15Å
204W83.1Confident83.1Confident231 Ų23199.3 Ų99.388%0.87552%0.519SS*.Hα-helixtrans-68.5-34.2177.8-172.462000112.8A200 V201 G206A200-W204 WeakPolarHBondContact O-CB 3.14Å; A200-W204 PolarHBondContact O-N 2.93Å; V201-W204 PolarHBondContact O-N 2.86Å; W204-G206 PolarHBondContact O-N 3.44Å
205S87.3Confident82.8Confident65 Ų6599.1 Ų99.146%0.45551%0.51SS..THydrogen-bonded Turntrans-75.8-2173.767.50000114V201 L202 L207V201-S205 WeakPolarHBondContact O-CB 3.25Å; V201-S205 PolarHBondContact O-N 3.5Å; V201-S205 PolarHBondContact O-OG 3.08Å; L202-S205 WeakPolarHBondContact CA-OG 3.24Å; L202-S205 PolarHBondContact O-OG 3.44Å; L202-S205 VanDerWaalsContact O-OG 3.13Å; S205-L207 VanDerWaalsContact C-N 3.26Å; S205-L207 PolarHBondContact O-N 3.01Å; S205-L207 WeakPolarHBondContact OG-CD1 3.45Å; S205-L207 WeakPolarHBondContact OG-CG 3.49Å
206G84.3Confident82.7Confident64 Ų64100.7 Ų100.766%0.6651%0.51SS*.THydrogen-bonded Turntrans76.26.5178.500000114.9L202 H203 W204L202-G206 PolarHBondContact O-N 2.85Å; H203-G206 PolarHBondContact O-N 3.26Å; W204-G206 PolarHBondContact O-N 3.44Å
207L84.6Confident82.9Confident128 Ų128100 Ų10067%0.6752%0.515SS*.SBendtrans-74.6-27.3-179.6-68173.5000112.7L202 S205L202-L207 HydrophobicContact CD2-CB 4.3Å; L202-L207 HydrophobicContact CD2-CD1 3.67Å; L202-L207 PolarHBondContact O-N 3.24Å; S205-L207 VanDerWaalsContact C-N 3.26Å; S205-L207 PolarHBondContact O-N 3.01Å; S205-L207 WeakPolarHBondContact OG-CD1 3.45Å; S205-L207 WeakPolarHBondContact OG-CG 3.49Å
208I85.4Confident82.9Confident65 Ų6598.6 Ų98.633%0.33351%0.507SS..SBendtrans-136.3145.9174.564.6178.5000111.3L202 H203 L210L202-I208 HydrophobicContact CB-CD1 3.62Å; L202-I208 HydrophobicContact CB-CG1 3.7Å; L202-I208 HydrophobicContact CD1-CD1 4.29Å; L202-I208 PolarHBondContact O-N 2.01Å; H203-I208 WeakPolarHBondContact CA-O 3.31Å; H203-I208 HydrophobicContact CB-CG1 4.26Å; H203-I208 PolarHBondContact ND1-O 3.02Å; I208-L210 HydrophobicContact CD1-CD1 3.93Å; I208-L210 HydrophobicContact CD1-CD2 4.16Å; I208-L210 HydrophobicContact CD1-CG 3.86Å; I208-L210 HydrophobicContact CG1-CG 4.16Å
209L82.1Confident82.8Confident172 Ų17299.4 Ų99.490%0.90151%0.506SS*.  trans-100.394.7173.4-135109.5000109.6
210L78.4Confident83Confident39 Ų39102 Ų10220%0.20452%0.523CS..  trans-82.4121.8173.7-69.7172.9000109.7A199 H203 I208 R212 I215A199-L210 HydrophobicContact CB-CD1 3.77Å; A199-L210 VanDerWaalsContact O-CD1 3.28Å; A199-L210 WeakPolarHBondContact O-CD1 3.28Å; H203-L210 HydrophobicContact CB-CB 4.34Å; H203-L210 HydrophobicContact CB-CD1 3.91Å; H203-L210 HydrophobicContact CB-CG 4.23Å; H203-L210 PolarHBondContact CE1-N 2.98Å; H203-L210 PolarHBondContact ND1-N 3.01Å; H203-L210 VanDerWaalsContact ND1-N 3.15Å; I208-L210 HydrophobicContact CD1-CD1 3.93Å; I208-L210 HydrophobicContact CD1-CD2 4.16Å; I208-L210 HydrophobicContact CD1-CG 3.86Å; I208-L210 HydrophobicContact CG1-CG 4.16Å; L210-R212 PolarHBondContact O-N 3.26Å; L210-R212 VanDerWaalsContact O-N 3.17Å; L210-I215 HydrophobicContact CB-CD1 3.74Å; L210-I215 HydrophobicContact CB-CG1 4.19Å; L210-I215 HydrophobicContact CD1-CD1 3.99Å; L210-I215 HydrophobicContact CD1-CG1 4.35Å
211R83.9Confident83.3Confident174 Ų174104.1 Ų104.166%0.65753%0.53SS*.  trans-65.8119.2173.5-161.8175.4-172.1-177.23.7108.2R213 L214R211-R213 PolarHBondContact O-N 3.43Å; R211-L214 WeakPolarHBondContact O-CB 3.43Å; R211-L214 PolarHBondContact O-N 3.32Å
212R79.6Confident83.2Confident201 Ų201102.4 Ų102.476%0.75852%0.518SS*.Hα-helixtrans-46.7-34.8179.9-170.4176.4178.6-173.40113.9L210 L214 I215 L216L210-R212 PolarHBondContact O-N 3.26Å; L210-R212 VanDerWaalsContact O-N 3.17Å; R212-L214 PolarHBondContact O-N 3.18Å; R212-I215 PolarHBondContact O-N 3.31Å; R212-L216 HydrophobicContact CG-CD1 4.1Å; R212-L216 WeakPolarHBondContact O-CG 3.45Å; R212-L216 PolarHBondContact O-N 3.46Å; R212-L216 VanDerWaalsContact O-N 3.08Å
213R82Confident83.3Confident192 Ų192101.4 Ų101.473%0.72552%0.519SS*.Hα-helixtrans-62.5-37175.8-65.4-173.5-178.8-178.4-0.4113.6R211 G217R211-R213 PolarHBondContact O-N 3.43Å; R213-G217 PolarHBondContact O-N 3.43Å
214L81.9Confident83.6Confident99 Ų9999.6 Ų99.652%0.51852%0.522SS..Hα-helixtrans-68.3-44.3178.6-178.665.6000111.1R211 R212 G217 L218R211-L214 WeakPolarHBondContact O-CB 3.43Å; R211-L214 PolarHBondContact O-N 3.32Å; R212-L214 PolarHBondContact O-N 3.18Å; L214-G217 PolarHBondContact O-N 3.49Å; L214-L218 HydrophobicContact CG-CD1 4.36Å; L214-L218 WeakPolarHBondContact O-CG 3.32Å; L214-L218 PolarHBondContact O-N 3.3Å
215I77.9Confident83.8Confident48 Ų4891.4 Ų91.425%0.24650%0.497CS..Hα-helixtrans-61.3-49.2176.8-63171.6000110.4L210 R212 G217 L218 L219L210-I215 HydrophobicContact CB-CD1 3.74Å; L210-I215 HydrophobicContact CB-CG1 4.19Å; L210-I215 HydrophobicContact CD1-CD1 3.99Å; L210-I215 HydrophobicContact CD1-CG1 4.35Å; R212-I215 PolarHBondContact O-N 3.31Å; I215-G217 VanDerWaalsContact C-N 3.27Å; I215-G217 PolarHBondContact O-N 3.09Å; I215-L218 PolarHBondContact O-N 3.06Å; I215-L219 HydrophobicContact CG2-CD1 3.91Å; I215-L219 HydrophobicContact CG2-CG 4.39Å; I215-L219 WeakPolarHBondContact O-CG 3.06Å; I215-L219 PolarHBondContact O-N 2.97Å
216L81.4Confident83.7Confident93 Ų9391.1 Ų91.149%0.48749%0.493SS..Hα-helixtrans-60.8-37.9177.5-71170.3000111.8R212 S220R212-L216 HydrophobicContact CG-CD1 4.1Å; R212-L216 WeakPolarHBondContact O-CG 3.45Å; R212-L216 PolarHBondContact O-N 3.46Å; R212-L216 VanDerWaalsContact O-N 3.08Å; L216-S220 VanDerWaalsContact O-CB 3.31Å; L216-S220 WeakPolarHBondContact O-CB 3.02Å; L216-S220 PolarHBondContact O-N 3Å; L216-S220 PolarHBondContact O-OG 2.8Å
217G85.2Confident84Confident35 Ų3594 Ų9436%0.36149%0.492SS..Hα-helixtrans-61.5-50.6174.100000112.6R213 L214 I215 L219 S220 V221R213-G217 PolarHBondContact O-N 3.43Å; L214-G217 PolarHBondContact O-N 3.49Å; I215-G217 VanDerWaalsContact C-N 3.27Å; I215-G217 PolarHBondContact O-N 3.09Å; G217-L219 PolarHBondContact O-N 2.82Å; G217-S220 PolarHBondContact O-N 2.9Å; G217-V221 WeakPolarHBondContact O-CG2 3.4Å; G217-V221 PolarHBondContact O-N 3.5Å
218L82.7Confident84.2Confident93 Ų9394 Ų9449%0.48749%0.492SS..Hα-helixtrans-62.8-43.1179.4-70.9171.6000112.5L214 I215 S220 V221 L222L214-L218 HydrophobicContact CG-CD1 4.36Å; L214-L218 WeakPolarHBondContact O-CG 3.32Å; L214-L218 PolarHBondContact O-N 3.3Å; I215-L218 PolarHBondContact O-N 3.06Å; L218-S220 VanDerWaalsContact C-N 3.32Å; L218-S220 PolarHBondContact O-N 3.39Å; L218-V221 PolarHBondContact O-N 2.97Å; L218-L222 WeakPolarHBondContact O-CB 3.19Å; L218-L222 PolarHBondContact O-N 2.83Å
219L83Confident84.2Confident82 Ų8291.8 Ų91.843%0.42948%0.481SS..Hα-helixtrans-63.5-38.9175.6-71.5174.1000111.9L196 I215 G217 L222 A223L196-L219 HydrophobicContact CD1-CD2 4.05Å; I215-L219 HydrophobicContact CG2-CD1 3.91Å; I215-L219 HydrophobicContact CG2-CG 4.39Å; I215-L219 WeakPolarHBondContact O-CG 3.06Å; I215-L219 PolarHBondContact O-N 2.97Å; G217-L219 PolarHBondContact O-N 2.82Å; L219-L222 PolarHBondContact O-N 3.32Å; L219-A223 VanDerWaalsContact O-CB 3.29Å; L219-A223 WeakPolarHBondContact O-CB 3.48Å; L219-A223 PolarHBondContact O-N 2.97Å
220S86.9Confident84.5Confident81 Ų8185.9 Ų85.957%0.56646%0.457SS*.Hα-helixtrans-66.4-40.1177.3-57.80000111.7L216 G217 L218 G224L216-S220 VanDerWaalsContact O-CB 3.31Å; L216-S220 WeakPolarHBondContact O-CB 3.02Å; L216-S220 PolarHBondContact O-N 3Å; L216-S220 PolarHBondContact O-OG 2.8Å; G217-S220 PolarHBondContact O-N 2.9Å; L218-S220 VanDerWaalsContact C-N 3.32Å; L218-S220 PolarHBondContact O-N 3.39Å; S220-G224 PolarHBondContact O-N 3.34Å
221V86.4Confident85Confident96 Ų9685.9 Ų85.958%0.58247%0.466SS*.Hα-helixtrans-64.3-47.8174.7171.70000110.7G217 L218 A223 G224 V225G217-V221 WeakPolarHBondContact O-CG2 3.4Å; G217-V221 PolarHBondContact O-N 3.5Å; L218-V221 PolarHBondContact O-N 2.97Å; V221-A223 PolarHBondContact O-N 2.94Å; V221-G224 PolarHBondContact O-N 3.49Å; V221-V225 HydrophobicContact CG1-CG2 4.43Å; V221-V225 WeakPolarHBondContact O-CG2 3.25Å; V221-V225 PolarHBondContact O-N 3.1Å
222L83.7Confident85.2Confident48 Ų4880.1 Ų80.125%0.25145%0.446SS..Hα-helixtrans-59.2-47.8178.3-176.862.9000111.2Y189 L192 L196 L218 L219 G224 V225 T226Y189-L222 HydrophobicContact CD1-CD1 4Å; Y189-L222 HydrophobicContact CE1-CD1 3.86Å; L192-L222 HydrophobicContact CD1-CD1 4.26Å; L196-L222 HydrophobicContact CD1-CD2 4.2Å; L218-L222 WeakPolarHBondContact O-CB 3.19Å; L218-L222 PolarHBondContact O-N 2.83Å; L219-L222 PolarHBondContact O-N 3.32Å; L222-G224 VanDerWaalsContact C-N 3.35Å; L222-G224 PolarHBondContact O-N 3.3Å; L222-V225 PolarHBondContact O-N 2.82Å; L222-T226 PolarHBondContact O-N 2.73Å; L222-T226 PolarHBondContact O-OG1 3.33Å; L222-T226 VanDerWaalsContact O-OG1 3.08Å
223A86.6Confident85.5Confident48 Ų4872.9 Ų72.940%0.39742%0.422SS..Hα-helixtrans-60.1-43.9176.100000111.8L219 V221 T226 I227L219-A223 VanDerWaalsContact O-CB 3.29Å; L219-A223 WeakPolarHBondContact O-CB 3.48Å; L219-A223 PolarHBondContact O-N 2.97Å; V221-A223 PolarHBondContact O-N 2.94Å; A223-T226 PolarHBondContact O-N 2.69Å; A223-I227 WeakPolarHBondContact O-CB 3.48Å; A223-I227 WeakPolarHBondContact O-CD1 3.35Å; A223-I227 WeakPolarHBondContact O-CG1 3.06Å; A223-I227 PolarHBondContact O-N 2.64Å
224G89.9Confident85.8Confident38 Ų3871.7 Ų71.739%0.39242%0.422SS..Hα-helixtrans-60-45.7176.600000112.8S220 V221 L222 I227 L228S220-G224 PolarHBondContact O-N 3.34Å; V221-G224 PolarHBondContact O-N 3.49Å; L222-G224 VanDerWaalsContact C-N 3.35Å; L222-G224 PolarHBondContact O-N 3.3Å; G224-I227 PolarHBondContact O-N 2.93Å; G224-L228 WeakPolarHBondContact O-CB 3.45Å; G224-L228 PolarHBondContact O-N 3.26Å
225V86.3Confident86.3Confident59 Ų5969.7 Ų69.736%0.35841%0.411SS..Hα-helixtrans-63.3-46.1176.2172.10000111L187 V221 L222 I227 L228 V229L187-V225 HydrophobicContact CD1-CG1 4.4Å; L187-V225 HydrophobicContact CD2-CG1 4.48Å; V221-V225 HydrophobicContact CG1-CG2 4.43Å; V221-V225 WeakPolarHBondContact O-CG2 3.25Å; V221-V225 PolarHBondContact O-N 3.1Å; L222-V225 PolarHBondContact O-N 2.82Å; V225-I227 PolarHBondContact O-N 2.75Å; V225-L228 PolarHBondContact O-N 3.04Å; V225-V229 HydrophobicContact CG1-CG2 4.34Å; V225-V229 WeakPolarHBondContact O-CG2 3.31Å; V225-V229 PolarHBondContact O-N 3.42Å
226T84.9Confident86.9Confident59 Ų5967.4 Ų67.436%0.36240%0.399SS..Hα-helixtrans-62-43.1178.3-61.10000111.8Y189 L222 A223 L228 V229 A230Y189-T226 WeakPolarHBondContact CE1-OG1 3.32Å; Y189-T226 PolarHBondContact OH-OG1 3.44Å; L222-T226 PolarHBondContact O-N 2.73Å; L222-T226 PolarHBondContact O-OG1 3.33Å; L222-T226 VanDerWaalsContact O-OG1 3.08Å; A223-T226 PolarHBondContact O-N 2.69Å; T226-L228 VanDerWaalsContact C-N 3.35Å; T226-V229 PolarHBondContact O-N 2.77Å; T226-A230 VanDerWaalsContact O-CB 3.26Å; T226-A230 WeakPolarHBondContact O-CB 3.46Å; T226-A230 PolarHBondContact O-N 3.27Å
227I90.3Very high87.5Confident125 Ų12564.2 Ų64.264%0.64138%0.384SS*.Hα-helixtrans-62.4-43.4175.9-70.4165.1000110.6A223 G224 V225 A230 G231A223-I227 WeakPolarHBondContact O-CB 3.48Å; A223-I227 WeakPolarHBondContact O-CD1 3.35Å; A223-I227 WeakPolarHBondContact O-CG1 3.06Å; A223-I227 PolarHBondContact O-N 2.64Å; G224-I227 PolarHBondContact O-N 2.93Å; V225-I227 PolarHBondContact O-N 2.75Å; I227-A230 PolarHBondContact O-N 2.87Å; I227-G231 PolarHBondContact O-N 3.07Å
228L89.5Confident87.8Confident128 Ų12865.7 Ų65.767%0.6738%0.379SS*.Hα-helixtrans-64.5-45.1179.5-176.2140.7000111.9G224 V225 T226 G231 F232G224-L228 WeakPolarHBondContact O-CB 3.45Å; G224-L228 PolarHBondContact O-N 3.26Å; V225-L228 PolarHBondContact O-N 3.04Å; T226-L228 VanDerWaalsContact C-N 3.35Å; L228-G231 PolarHBondContact O-N 2.87Å; L228-F232 WeakPolarHBondContact O-CB 3.47Å; L228-F232 PolarHBondContact O-N 3.41Å
229V86.3Confident88.3Confident18 Ų1861.7 Ų61.711%0.10936%0.358CS..Hα-helixtrans-65.1-44.5177.1172.60000111.1I183 L187 V225 T226 F232 I233I183-V229 HydrophobicContact CB-CG1 4.18Å; I183-V229 HydrophobicContact CD1-CG1 4.39Å; I183-V229 HydrophobicContact CG2-CG1 3.98Å; I183-V229 HydrophobicContact CG2-CG2 4.14Å; L187-V229 HydrophobicContact CD1-CG2 4.15Å; V225-V229 HydrophobicContact CG1-CG2 4.34Å; V225-V229 WeakPolarHBondContact O-CG2 3.31Å; V225-V229 PolarHBondContact O-N 3.42Å; T226-V229 PolarHBondContact O-N 2.77Å; V229-F232 PolarHBondContact O-N 2.73Å; V229-I233 HydrophobicContact CG1-CD1 4.04Å; V229-I233 WeakPolarHBondContact O-CG1 3.48Å; V229-I233 PolarHBondContact O-N 3.15Å
230A86.9Confident88.9Confident47 Ų4757.9 Ų57.939%0.38834%0.339SS..Hα-helixtrans-64.7-40.2177.200000112T226 I227 I233 K234T226-A230 VanDerWaalsContact O-CB 3.26Å; T226-A230 WeakPolarHBondContact O-CB 3.46Å; T226-A230 PolarHBondContact O-N 3.27Å; I227-A230 PolarHBondContact O-N 2.87Å; A230-I233 PolarHBondContact O-N 2.85Å; A230-K234 WeakPolarHBondContact O-CG 3.49Å; A230-K234 PolarHBondContact O-N 3.11Å
231G89.5Confident89.3Confident39 Ų3954 Ų5440%0.40231%0.312SS..Hα-helixtrans-63.2-42.217400000112.2I227 L228 K234 I235I227-G231 PolarHBondContact O-N 3.07Å; L228-G231 PolarHBondContact O-N 2.87Å; G231-K234 PolarHBondContact O-N 3.49Å; G231-I235 PolarHBondContact O-N 3.25Å
232F87.8Confident89.7Confident54 Ų5449.5 Ų49.524%0.23728%0.284CS..Hα-helixtrans-60.3-50.1175-179.2-102.5000111.7F107 F181 I183 L228 V229 K234 I235 I236F107-F232 AromaticContact CE1-CZ 3.86Å; F107-F232 HydrophobicContact CE1-CZ 3.86Å; F107-F232 AromaticContact CZ-CZ 3.93Å; F107-F232 HydrophobicContact CZ-CZ 3.93Å; F181-F232 HydrophobicContact CD1-CE1 4.41Å; I183-F232 HydrophobicContact CD1-CD1 4.09Å; I183-F232 HydrophobicContact CD1-CE1 4.26Å; L228-F232 WeakPolarHBondContact O-CB 3.47Å; L228-F232 PolarHBondContact O-N 3.41Å; V229-F232 PolarHBondContact O-N 2.73Å; F232-K234 VanDerWaalsContact C-N 3.25Å; F232-K234 PolarHBondContact O-N 3.12Å; F232-I235 VanDerWaalsContact O-CG2 3.28Å; F232-I235 WeakPolarHBondContact O-CG2 3.34Å; F232-I235 PolarHBondContact O-N 2.72Å; F232-I236 HydrophobicContact CD1-CD1 4.37Å; F232-I236 HydrophobicContact CD1-CG1 4.4Å; F232-I236 HydrophobicContact CE1-CD1 3.7Å; F232-I236 HydrophobicContact CE1-CG1 4.14Å; F232-I236 HydrophobicContact CE2-CD1 4.12Å; F232-I236 HydrophobicContact CZ-CD1 3.57Å; F232-I236 HydrophobicContact CZ-CG1 4.44Å; F232-I236 WeakPolarHBondContact O-CG1 3.42Å; F232-I236 PolarHBondContact O-N 3.01Å; F232-I236 VanDerWaalsContact O-N 3.13Å
233I87.4Confident90.4Very high48 Ų4847.4 Ų47.425%0.24627%0.273CS..Hα-helixtrans-59.4-38.9177.7-67165.4000111T179 V229 A230 I235T179-I233 HydrophobicContact CG2-CD1 4.31Å; T179-I233 HydrophobicContact CG2-CG2 4.29Å; V229-I233 HydrophobicContact CG1-CD1 4.04Å; V229-I233 WeakPolarHBondContact O-CG1 3.48Å; V229-I233 PolarHBondContact O-N 3.15Å; A230-I233 PolarHBondContact O-N 2.85Å; I233-I235 VanDerWaalsContact C-N 3.31Å; I233-I235 PolarHBondContact O-N 2.81Å
234K88.3Confident90.9Very high168 Ų16845.2 Ų45.273%0.7326%0.255SS*.Hα-helixtrans-67.8-26.6177.1-77.4-170.9176-170.90114.2A230 G231 F232A230-K234 WeakPolarHBondContact O-CG 3.49Å; A230-K234 PolarHBondContact O-N 3.11Å; G231-K234 PolarHBondContact O-N 3.49Å; F232-K234 VanDerWaalsContact C-N 3.25Å; F232-K234 PolarHBondContact O-N 3.12Å
235I90.8Very high91.3Very high56 Ų5647.5 Ų47.529%0.28725%0.251SS..Hα-helixtrans-88.6-21.8-179.7-153.7166.9000112.9G231 F232 I233 P237 Y238 L239 L568G231-I235 PolarHBondContact O-N 3.25Å; F232-I235 VanDerWaalsContact O-CG2 3.28Å; F232-I235 WeakPolarHBondContact O-CG2 3.34Å; F232-I235 PolarHBondContact O-N 2.72Å; I233-I235 VanDerWaalsContact C-N 3.31Å; I233-I235 PolarHBondContact O-N 2.81Å; I235-P237 VanDerWaalsContact C-N 3.32Å; I235-P237 VanDerWaalsContact O-N 3.15Å; I235-Y238 WeakPolarHBondContact O-CB 3.45Å; I235-Y238 PolarHBondContact O-N 2.89Å; I235-L239 HydrophobicContact CG1-CD2 4.46Å; I235-L239 HydrophobicContact CG1-CG 4.3Å; I235-L239 HydrophobicContact CG2-CD1 3.82Å; I235-L239 HydrophobicContact CG2-CG 4.31Å; I235-L239 PolarHBondContact O-N 2.78Å; I235-L568 HydrophobicContact CD1-CD2 3.84Å; I235-L568 HydrophobicContact CG1-CD2 4.31Å
236I91.4Very high91.8Very high0 Ų047.3 Ų47.30%025%0.249CC..Hα-helixtrans-45.5-46.6-179.2-74.5-59.8000113.9F107 D172 F181 F232 Y238 L239 N240F107-I236 HydrophobicContact CE1-CD1 3.88Å; D172-I236 HydrophobicContact CB-CB 4.44Å; D172-I236 HydrophobicContact CB-CG2 3.51Å; F181-I236 HydrophobicContact CD2-CD1 4.19Å; F181-I236 HydrophobicContact CD2-CG1 3.98Å; F181-I236 HydrophobicContact CD2-CG2 4.38Å; F181-I236 HydrophobicContact CE2-CD1 3.67Å; F181-I236 HydrophobicContact CE2-CG1 3.85Å; F181-I236 HydrophobicContact CE2-CG2 3.83Å; F181-I236 HydrophobicContact CZ-CD1 3.96Å; F232-I236 HydrophobicContact CD1-CD1 4.37Å; F232-I236 HydrophobicContact CD1-CG1 4.4Å; F232-I236 HydrophobicContact CE1-CD1 3.7Å; F232-I236 HydrophobicContact CE1-CG1 4.14Å; F232-I236 HydrophobicContact CE2-CD1 4.12Å; F232-I236 HydrophobicContact CZ-CD1 3.57Å; F232-I236 HydrophobicContact CZ-CG1 4.44Å; F232-I236 WeakPolarHBondContact O-CG1 3.42Å; F232-I236 PolarHBondContact O-N 3.01Å; F232-I236 VanDerWaalsContact O-N 3.13Å; I236-Y238 PolarHBondContact O-N 2.69Å; I236-L239 PolarHBondContact O-N 3.22Å; I236-N240 HydrophobicContact CG2-CB 4.46Å; I236-N240 PolarHBondContact O-N 2.93Å
237P92.9Very high92.3Very high27 Ų2749.1 Ų49.118%0.17525%0.253CS..Hα-helixtrans-60.8-38.2-176.5-22.934.4000112.2D172 I235 L239 C241 P253D172-P237 VanDerWaalsContact O-CG 3.25Å; D172-P237 WeakPolarHBondContact O-CG 3.34Å; I235-P237 VanDerWaalsContact C-N 3.32Å; I235-P237 VanDerWaalsContact O-N 3.15Å; P237-L239 VanDerWaalsContact C-N 3.29Å; P237-L239 PolarHBondContact O-N 3.5Å; P237-C241 VanDerWaalsContact CA-SG 3.54Å; P237-C241 WeakPolarHBondContact O-CB 3.47Å; P237-C241 PolarHBondContact O-N 3.28Å; P237-P253 HydrophobicContact CB-CB 4.45Å
238Y92.6Very high92.6Very high65 Ų6546.5 Ų46.526%0.25525%0.246SC..Hα-helixtrans-69.2-26.4176.9-58.2-81000112.9I235 I236 Q252 P253 L568 Q570I235-Y238 WeakPolarHBondContact O-CB 3.45Å; I235-Y238 PolarHBondContact O-N 2.89Å; I236-Y238 PolarHBondContact O-N 2.69Å; Y238-Q252 WeakPolarHBondContact O-CG 3.4Å; Y238-Q252 PolarHBondContact O-NE2 3.12Å; Y238-P253 HydrophobicContact CD1-CG 4.2Å; Y238-P253 HydrophobicContact CE1-CG 4.01Å; Y238-L568 WeakPolarHBondContact CB-O 3.26Å; Y238-L568 HydrophobicContact CD1-CB 4.39Å; Y238-Q570 HydrophobicContact CD1-CG 3.64Å; Y238-Q570 HydrophobicContact CE1-CG 3.62Å
239L92.7Very high92.9Very high9 Ų941.5 Ų41.55%0.04722%0.219CC..Hα-helixtrans-88.4-34.8179.7-58.4-175.2000112.8N108 I235 I236 P237 I242 W554 Q559N108-L239 PolarHBondContact ND2-O 2.51Å; I235-L239 HydrophobicContact CG1-CD2 4.46Å; I235-L239 HydrophobicContact CG1-CG 4.3Å; I235-L239 HydrophobicContact CG2-CD1 3.82Å; I235-L239 HydrophobicContact CG2-CG 4.31Å; I235-L239 PolarHBondContact O-N 2.78Å; I236-L239 PolarHBondContact O-N 3.22Å; P237-L239 VanDerWaalsContact C-N 3.29Å; P237-L239 PolarHBondContact O-N 3.5Å; L239-I242 WeakPolarHBondContact O-CD1 3.39Å; L239-W554 HydrophobicContact CD1-CZ2 4.11Å; L239-Q559 HydrophobicContact CD2-CG 4Å; L239-Q559 PolarHBondContact O-NE2 3.48Å
240N95.3Very high93.4Very high3 Ų341.5 Ų41.52%0.01622%0.219CC..Hα-helixtrans-113.4-27.1-167-78.7-16.5000114.8I106 F107 N108 L167 L170 I236 I242I106-N240 PolarHBondContact O-ND2 3.3Å; F107-N240 WeakPolarHBondContact CA-OD1 3.46Å; N108-N240 PolarHBondContact N-OD1 2.65Å; N108-N240 VanDerWaalsContact N-OD1 3.11Å; N108-N240 VanDerWaalsContact ND2-C 3.32Å; N108-N240 VanDerWaalsContact ND2-CA 3.3Å; N108-N240 WeakPolarHBondContact ND2-CA 3.21Å; N108-N240 PolarHBondContact ND2-O 2.75Å; L167-N240 HydrophobicContact CD2-CB 4.07Å; L170-N240 HydrophobicContact CD1-CB 4.27Å; I236-N240 HydrophobicContact CG2-CB 4.46Å; I236-N240 PolarHBondContact O-N 2.93Å; N240-I242 VanDerWaalsContact C-N 3.34Å; N240-I242 PolarHBondContact O-N 3.13Å; N240-I242 VanDerWaalsContact O-N 3.09Å
241C95.6Very high93.8Very high0 Ų039.9 Ų39.90%020%0.204CC..  trans-9270.8-173.9-49.20000110C173 P237 P253 F254C173-C241 WeakPolarHBondContact CA-SG 3.32Å; C173-C241 HydrophobicContact CB-CB 3.78Å; C173-C241 WeakPolarHBondContact CB-SG 3.29Å; C173-C241 WeakPolarHBondContact SG-CB 3.25Å; C173-C241 CovalentContact SG-SG 2.03Å; C173-C241 PolarHBondContact SG-SG 2.96Å; P237-C241 VanDerWaalsContact CA-SG 3.54Å; P237-C241 WeakPolarHBondContact O-CB 3.47Å; P237-C241 PolarHBondContact O-N 3.28Å; C241-P253 HydrophobicContact CB-CB 4.15Å; C241-P253 CarbonylContact O-C 3.58Å; C241-P253 WeakPolarHBondContact O-CA 3.35Å; C241-F254 HydrophobicContact CB-CD1 4.02Å; C241-F254 HydrophobicContact CB-CE1 3.71Å; C241-F254 HydrophobicContact CB-CE2 4.33Å; C241-F254 HydrophobicContact CB-CG 4.48Å; C241-F254 HydrophobicContact CB-CZ 3.87Å; C241-F254 VanDerWaalsContact O-CD1 3.31Å; C241-F254 WeakPolarHBondContact O-CD1 2.94Å; C241-F254 PolarHBondContact O-N 2.87Å
242I96.1Very high94Very high0 Ų038.1 Ų38.10%019%0.185CC..  trans-112.8128.7-171.9-48.4-178.7000110.2N108 I165 P166 L239 N240 F244 I249 Q252 P560N108-I242 WeakPolarHBondContact ND2-CD1 3.47Å; I165-I242 WeakPolarHBondContact CG2-O 3.36Å; P166-I242 WeakPolarHBondContact CD-O 3.44Å; L239-I242 WeakPolarHBondContact O-CD1 3.39Å; N240-I242 VanDerWaalsContact C-N 3.34Å; N240-I242 PolarHBondContact O-N 3.13Å; N240-I242 VanDerWaalsContact O-N 3.09Å; I242-F244 HydrophobicContact CB-CD2 4.41Å; I242-F244 HydrophobicContact CB-CE2 4.1Å; I242-F244 HydrophobicContact CG2-CD2 3.77Å; I242-F244 HydrophobicContact CG2-CE2 3.44Å; I242-F244 VanDerWaalsContact CG2-CE2 3.44Å; I242-F244 HydrophobicContact CG2-CZ 4.45Å; I242-I249 HydrophobicContact CG2-CB 4.14Å; I242-I249 HydrophobicContact CG2-CD1 4.05Å; I242-I249 HydrophobicContact CG2-CG1 3.77Å; I242-I249 HydrophobicContact CG2-CG2 3.41Å; I242-I249 VanDerWaalsContact CG2-CG2 3.41Å; I242-Q252 VanDerWaalsContact CD1-NE2 3.3Å; I242-Q252 HydrophobicContact CG1-CG 4.01Å; I242-Q252 HydrophobicContact CG2-CB 4.49Å; I242-P560 HydrophobicContact CD1-CB 4.07Å; I242-P560 HydrophobicContact CD1-CG 3.45Å; I242-P560 VanDerWaalsContact CD1-CG 3.45Å
243L97.5Very high94.3Very high4 Ų437.5 Ų37.52%0.02119%0.186CC..EExtended strand (participates in β ladder)trans-100.8128.1173.1-174.768.7000109.7F163 I165 V250 E251 F254 L259F163-L243 HydrophobicContact CE1-CD1 4.43Å; F163-L243 HydrophobicContact CE2-CD2 4.13Å; F163-L243 HydrophobicContact CE2-CG 4.4Å; F163-L243 HydrophobicContact CZ-CD1 4.22Å; F163-L243 HydrophobicContact CZ-CD2 3.93Å; F163-L243 HydrophobicContact CZ-CG 4.41Å; I165-L243 HydrophobicContact CG2-CD1 4.14Å; L243-V250 HydrophobicContact CB-CG2 4.11Å; L243-V250 HydrophobicContact CD2-CG2 3.85Å; L243-V250 HydrophobicContact CG-CG2 3.7Å; L243-V250 WeakPolarHBondContact O-CG2 3.03Å; L243-V250 PolarHBondContact O-N 3.07Å; L243-E251 HydrophobicContact CB-CB 3.86Å; L243-E251 HydrophobicContact CD2-CB 4.06Å; L243-E251 PolarHBondContact N-O 3.14Å; L243-E251 PolarHBondContact O-N 3.44Å; L243-F254 HydrophobicContact CB-CB 3.84Å; L243-F254 HydrophobicContact CB-CD1 4.41Å; L243-L259 HydrophobicContact CD1-CD1 4.14Å; L243-L259 HydrophobicContact CD2-CD1 4.26Å
244F97.5Very high94.7Very high2 Ų235.5 Ų35.51%0.00918%0.176CC..EExtended strand (participates in β ladder)trans-107.8147.2179.2-85.4-109000111.1L142 H150 F162 F163 G164 P166 I242 S248 I249 P560L142-F244 HydrophobicContact CD1-CZ 4.39Å; L142-F244 HydrophobicContact CD2-CE2 4.41Å; L142-F244 HydrophobicContact CD2-CZ 4.02Å; H150-F244 AromaticContact NE2-CE1 3.83Å; F162-F244 HydrophobicContact CD1-CB 3.95Å; F162-F244 HydrophobicContact CE1-CB 3.59Å; F162-F244 HydrophobicContact CE1-CG 4.33Å; F163-F244 WeakPolarHBondContact CA-O 3.48Å; G164-F244 PolarHBondContact N-O 3.36Å; G164-F244 PolarHBondContact O-N 3.03Å; P166-F244 HydrophobicContact CG-CD2 3.87Å; P166-F244 HydrophobicContact CG-CE2 3.79Å; I242-F244 HydrophobicContact CB-CD2 4.41Å; I242-F244 HydrophobicContact CB-CE2 4.1Å; I242-F244 HydrophobicContact CG2-CD2 3.77Å; I242-F244 HydrophobicContact CG2-CE2 3.44Å; I242-F244 VanDerWaalsContact CG2-CE2 3.44Å; I242-F244 HydrophobicContact CG2-CZ 4.45Å; F244-S248 CarbonylContact C-O 3.56Å; F244-S248 WeakPolarHBondContact CA-O 3.48Å; F244-I249 HydrophobicContact CD2-CG1 4.36Å; F244-I249 HydrophobicContact CE1-CG1 3.97Å; F244-I249 HydrophobicContact CE2-CG1 3.79Å; F244-I249 HydrophobicContact CZ-CD1 4.24Å; F244-I249 HydrophobicContact CZ-CG1 3.57Å; F244-P560 HydrophobicContact CZ-CB 4.28Å
245R97.7Very high94.8Very high86 Ų8630.3 Ų30.333%0.32516%0.158SC..EExtended strand (participates in β ladder)trans-123.8116.2156.6-173.3-173.8-64.8-96.21.3107.1Y161 F162 F163 H247 S248 V250 E266Y161-R245 HydrophobicContact CE2-CG 4.15Å; Y161-R245 PolarHBondContact OH-NH1 3.46Å; F162-R245 CarbonylContact O-C 3.53Å; F162-R245 WeakPolarHBondContact O-CA 3.27Å; F163-R245 HydrophobicContact CD2-CB 4.4Å; R245-H247 PolarHBondContact O-N 2.9Å; R245-S248 PolarHBondContact N-O 2.98Å; R245-S248 PolarHBondContact O-N 3Å; R245-V250 HydrophobicContact CB-CG1 3.52Å; R245-V250 HydrophobicContact CB-CG2 4.45Å; R245-E266 IonicContact CZ-OE1 2.93Å; R245-E266 IonicContact NH1-OE1 3.68Å; R245-E266 PolarHBondContact NH1-OE1 2.75Å; R245-E266 IonicContact NH1-OE2 2.65Å; R245-E266 PolarHBondContact NH1-OE2 3.22Å; R245-E266 IonicContact NH2-OE1 3.83Å; R245-E266 PolarHBondContact NH2-OE1 3.2Å
246D97.1Very high94.9Very high56 Ų5628.1 Ų28.130%0.29915%0.147SC..THydrogen-bonded Turntrans48.5-120.7-167.4-57.5-48.5000110.4H153 Y161 F162H153-D246 PolarHBondContact CE1-O 3.04Å; H153-D246 PolarHBondContact NE2-O 3.4Å; Y161-D246 VanDerWaalsContact CD2-OD1 3.28Å; Y161-D246 WeakPolarHBondContact CD2-OD1 2.96Å; F162-D246 PolarHBondContact N-OD1 3.4Å; F162-D246 VanDerWaalsContact N-OD1 3.12Å; F162-D246 PolarHBondContact O-N 2.95Å
247H96.1Very high94.6Very high96 Ų9633.2 Ų33.244%0.44417%0.171SC..THydrogen-bonded Turntrans-92.84.2-179.9-5686.5000113.3H150 H153 S155 R245H150-H247 AromaticContact CG-CD2 3.9Å; H153-H247 AromaticContact ND1-CD2 3.93Å; H153-H247 AromaticContact ND1-NE2 3.76Å; S155-H247 PolarHBondContact OG-NE2 3.29Å; R245-H247 PolarHBondContact O-N 2.9Å
248S95.6Very high94.6Very high71 Ų7135.2 Ų35.250%0.49718%0.18SC..EExtended strand (participates in β ladder)trans-107.5134.6-175.5-63.30000111.4F244 R245 V250F244-S248 CarbonylContact C-O 3.56Å; F244-S248 WeakPolarHBondContact CA-O 3.48Å; R245-S248 PolarHBondContact N-O 2.98Å; R245-S248 PolarHBondContact O-N 3Å; S248-V250 PolarHBondContact O-N 3.09Å
249I96.2Very high94.7Very high22 Ų2232.1 Ų32.111%0.11317%0.168CC..EExtended strand (participates in β ladder)trans-75.2121170.3-58.2169.3000108.4I242 F244 Q252 P560 C562I242-I249 HydrophobicContact CG2-CB 4.14Å; I242-I249 HydrophobicContact CG2-CD1 4.05Å; I242-I249 HydrophobicContact CG2-CG1 3.77Å; I242-I249 HydrophobicContact CG2-CG2 3.41Å; I242-I249 VanDerWaalsContact CG2-CG2 3.41Å; F244-I249 HydrophobicContact CD2-CG1 4.36Å; F244-I249 HydrophobicContact CE1-CG1 3.97Å; F244-I249 HydrophobicContact CE2-CG1 3.79Å; F244-I249 HydrophobicContact CZ-CD1 4.24Å; F244-I249 HydrophobicContact CZ-CG1 3.57Å; I249-Q252 HydrophobicContact CG2-CB 3.92Å; I249-P560 HydrophobicContact CD1-CB 3.87Å; I249-C562 HydrophobicContact CB-CB 3.76Å; I249-C562 HydrophobicContact CD1-CB 4.08Å; I249-C562 HydrophobicContact CG2-CB 3.64Å
250V95.4Very high95Very high18 Ų1831.7 Ų31.711%0.10917%0.166CC..EExtended strand (participates in β ladder)trans-101.6-26.8179.6-65.40000112.6L243 R245 S248 Q573L243-V250 HydrophobicContact CB-CG2 4.11Å; L243-V250 HydrophobicContact CD2-CG2 3.85Å; L243-V250 HydrophobicContact CG-CG2 3.7Å; L243-V250 WeakPolarHBondContact O-CG2 3.03Å; L243-V250 PolarHBondContact O-N 3.07Å; R245-V250 HydrophobicContact CB-CG1 3.52Å; R245-V250 HydrophobicContact CB-CG2 4.45Å; S248-V250 PolarHBondContact O-N 3.09Å; V250-Q573 PolarHBondContact O-N 3.2Å
251E95.4Very high95.1Very high14 Ų1432.5 Ų32.57%0.06517%0.169CC..EExtended strand (participates in β ladder)trans-147127.1179.2-147.6-178.9148.700110.6L243 F254 T255 K262 Q572L243-E251 HydrophobicContact CB-CB 3.86Å; L243-E251 HydrophobicContact CD2-CB 4.06Å; L243-E251 PolarHBondContact N-O 3.14Å; L243-E251 PolarHBondContact O-N 3.44Å; E251-F254 HydrophobicContact CB-CB 4.23Å; E251-F254 HydrophobicContact CG-CB 4.45Å; E251-T255 VanDerWaalsContact OE1-CB 3.25Å; E251-T255 WeakPolarHBondContact OE1-CB 3.25Å; E251-T255 PolarHBondContact OE1-N 3.3Å; E251-T255 PolarHBondContact OE1-OG1 2.74Å; E251-K262 IonicContact OE2-NZ 2.7Å; E251-K262 PolarHBondContact OE2-NZ 2.94Å; E251-K262 VanDerWaalsContact OE2-NZ 3.16Å; E251-Q572 HydrophobicContact CG-CG 4.18Å
252Q95.1Very high95.2Very high2 Ų236.3 Ų36.31%0.00919%0.186CC..EExtended strand (participates in β ladder)trans-151.3115.9178.7-171.9171.512.300110.3Y238 I242 I249 P560 C562 C569 Q570 C571Y238-Q252 WeakPolarHBondContact O-CG 3.4Å; Y238-Q252 PolarHBondContact O-NE2 3.12Å; I242-Q252 VanDerWaalsContact CD1-NE2 3.3Å; I242-Q252 HydrophobicContact CG1-CG 4.01Å; I242-Q252 HydrophobicContact CG2-CB 4.49Å; I249-Q252 HydrophobicContact CG2-CB 3.92Å; Q252-P560 PolarHBondContact NE2-O 2.93Å; Q252-C562 PolarHBondContact OE1-SG 2.86Å; Q252-C569 WeakPolarHBondContact CB-O 3.44Å; Q252-C569 HydrophobicContact CG-CB 4.49Å; Q252-C569 WeakPolarHBondContact CG-O 3.36Å; Q252-C569 PolarHBondContact OE1-O 3.46Å; Q252-C569 VanDerWaalsContact OE1-O 3.09Å; Q252-Q570 VanDerWaalsContact O-CA 3.28Å; Q252-Q570 WeakPolarHBondContact O-CA 3.4Å; Q252-C571 PolarHBondContact N-O 3.43Å; Q252-C571 PolarHBondContact O-N 3.37Å
253P94.6Very high95.3Very high40 Ų4036.4 Ų36.426%0.2619%0.186SC..SBendcis-64.8149.9-1531.5-34.1000110.8P237 Y238 C241P237-P253 HydrophobicContact CB-CB 4.45Å; Y238-P253 HydrophobicContact CD1-CG 4.2Å; Y238-P253 HydrophobicContact CE1-CG 4.01Å; C241-P253 HydrophobicContact CB-CB 4.15Å; C241-P253 CarbonylContact O-C 3.58Å; C241-P253 WeakPolarHBondContact O-CA 3.35Å
254F94.2Very high95.3Very high7 Ų736.2 Ų36.23%0.03119%0.186CC..PPolyproline II helixtrans-70.3153173.264.2-114.3000112.3I165 C173 C241 L243 E251 L256 L259I165-F254 HydrophobicContact CB-CE1 4.42Å; I165-F254 HydrophobicContact CG2-CD1 3.8Å; I165-F254 HydrophobicContact CG2-CE1 3.57Å; I165-F254 HydrophobicContact CG2-CZ 4.37Å; C173-F254 HydrophobicContact CB-CE2 3.81Å; C173-F254 HydrophobicContact CB-CZ 3.79Å; C241-F254 HydrophobicContact CB-CD1 4.02Å; C241-F254 HydrophobicContact CB-CE1 3.71Å; C241-F254 HydrophobicContact CB-CE2 4.33Å; C241-F254 HydrophobicContact CB-CG 4.48Å; C241-F254 HydrophobicContact CB-CZ 3.87Å; C241-F254 VanDerWaalsContact O-CD1 3.31Å; C241-F254 WeakPolarHBondContact O-CD1 2.94Å; C241-F254 PolarHBondContact O-N 2.87Å; L243-F254 HydrophobicContact CB-CB 3.84Å; L243-F254 HydrophobicContact CB-CD1 4.41Å; E251-F254 HydrophobicContact CB-CB 4.23Å; E251-F254 HydrophobicContact CG-CB 4.45Å; F254-L256 HydrophobicContact CD2-CD2 3.81Å; F254-L256 HydrophobicContact CD2-CG 4.12Å; F254-L256 HydrophobicContact CE2-CD2 3.28Å; F254-L256 HydrophobicContact CE2-CG 3.73Å; F254-L256 HydrophobicContact CZ-CD2 4.26Å; F254-L259 HydrophobicContact CD2-CD2 4.28Å
255T92Very high95.4Very high59 Ų5942.7 Ų42.736%0.36221%0.211SC..PPolyproline II helixtrans-98123.8171.9-40.90000108.9E251 E257E251-T255 VanDerWaalsContact OE1-CB 3.25Å; E251-T255 WeakPolarHBondContact OE1-CB 3.25Å; E251-T255 PolarHBondContact OE1-N 3.3Å; E251-T255 PolarHBondContact OE1-OG1 2.74Å; T255-E257 VanDerWaalsContact C-N 3.28Å; T255-E257 HydrophobicContact CG2-CB 4.05Å; T255-E257 PolarHBondContact O-N 3.11Å
256L91.9Very high95.4Very high10 Ų1039.8 Ų39.85%0.05220%0.201CC..  trans-71.5-25.1177.7-71.2175.8000112.6Q174 F254 N258 L259 L286 A291 F293Q174-L256 HydrophobicContact CB-CD1 3.87Å; Q174-L256 HydrophobicContact CG-CD1 4.23Å; F254-L256 HydrophobicContact CD2-CD2 3.81Å; F254-L256 HydrophobicContact CD2-CG 4.12Å; F254-L256 HydrophobicContact CE2-CD2 3.28Å; F254-L256 HydrophobicContact CE2-CG 3.73Å; F254-L256 HydrophobicContact CZ-CD2 4.26Å; L256-N258 PolarHBondContact O-N 2.92Å; L256-N258 VanDerWaalsContact O-N 3.11Å; L256-L259 HydrophobicContact CD2-CD2 3.91Å; L256-L259 WeakPolarHBondContact O-CB 3.42Å; L256-L259 PolarHBondContact O-N 3.26Å; L256-L286 HydrophobicContact CD2-CD2 4.31Å; L256-A291 HydrophobicContact CD1-CB 4.34Å; L256-F293 HydrophobicContact CB-CB 4.08Å; L256-F293 HydrophobicContact CB-CD1 4Å; L256-F293 HydrophobicContact CB-CD2 3.92Å; L256-F293 HydrophobicContact CB-CE1 4.36Å; L256-F293 HydrophobicContact CB-CE2 4.24Å; L256-F293 HydrophobicContact CB-CG 3.75Å; L256-F293 HydrophobicContact CB-CZ 4.43Å; L256-F293 HydrophobicContact CD1-CD1 3.92Å; L256-F293 HydrophobicContact CD1-CE1 4.39Å; L256-F293 HydrophobicContact CD1-CG 4.35Å; L256-F293 HydrophobicContact CD2-CD1 3.83Å; L256-F293 HydrophobicContact CD2-CE1 3.49Å; L256-F293 VanDerWaalsContact CD2-CE1 3.49Å; L256-F293 HydrophobicContact CD2-CE2 4.34Å; L256-F293 HydrophobicContact CD2-CG 4.4Å; L256-F293 HydrophobicContact CD2-CZ 3.72Å; L256-F293 HydrophobicContact CG-CD1 4.13Å; L256-F293 HydrophobicContact CG-CE1 4.29Å; L256-F293 HydrophobicContact CG-CG 4.39Å; L256-F293 WeakPolarHBondContact O-CD2 3.44Å; L256-F293 WeakPolarHBondContact O-CE2 3.16Å
257E85.4Confident95.5Very high106 Ų10637.1 Ų37.150%0.49519%0.187SC..THydrogen-bonded Turntrans-57.6119.9177-172.3163.1-145.900110.6T255 L259T255-E257 VanDerWaalsContact C-N 3.28Å; T255-E257 HydrophobicContact CG2-CB 4.05Å; T255-E257 PolarHBondContact O-N 3.11Å; E257-L259 VanDerWaalsContact C-N 3.28Å; E257-L259 PolarHBondContact O-N 2.71Å
258N92.6Very high95.6Very high69 Ų6933.6 Ų33.637%0.36917%0.172SC..THydrogen-bonded Turntrans66.612.6-176.5-51.3-35.8000116.8L256 T260 Q261 K262 S295L256-N258 PolarHBondContact O-N 2.92Å; L256-N258 VanDerWaalsContact O-N 3.11Å; N258-T260 VanDerWaalsContact C-N 3.3Å; N258-T260 PolarHBondContact O-N 2.97Å; N258-Q261 WeakPolarHBondContact O-CB 3.39Å; N258-Q261 PolarHBondContact O-N 3.46Å; N258-Q261 VanDerWaalsContact O-N 3.16Å; N258-Q261 PolarHBondContact O-OE1 3.26Å; N258-K262 PolarHBondContact O-N 2.95Å; N258-S295 WeakPolarHBondContact OD1-CB 3.33Å
259L95.4Very high95.8Very high1 Ų133.1 Ų33.11%0.00516%0.164CC..Hα-helixtrans-65-34.1-177.5-175.355.9000112.2L243 F254 L256 E257 Q261 K262 M263 L286 F293L243-L259 HydrophobicContact CD1-CD1 4.14Å; L243-L259 HydrophobicContact CD2-CD1 4.26Å; F254-L259 HydrophobicContact CD2-CD2 4.28Å; L256-L259 HydrophobicContact CD2-CD2 3.91Å; L256-L259 WeakPolarHBondContact O-CB 3.42Å; L256-L259 PolarHBondContact O-N 3.26Å; E257-L259 VanDerWaalsContact C-N 3.28Å; E257-L259 PolarHBondContact O-N 2.71Å; L259-Q261 PolarHBondContact O-N 3.42Å; L259-K262 HydrophobicContact CD1-CB 4.47Å; L259-K262 HydrophobicContact CD1-CD 4.34Å; L259-K262 PolarHBondContact O-N 3.36Å; L259-M263 HydrophobicContact CG-SD 4.44Å; L259-M263 VanDerWaalsContact O-CG 3.31Å; L259-M263 WeakPolarHBondContact O-CG 3.35Å; L259-M263 PolarHBondContact O-N 3.38Å; L259-L286 HydrophobicContact CD2-CD2 3.44Å; L259-L286 VanDerWaalsContact CD2-CD2 3.44Å; L259-L286 HydrophobicContact CG-CD2 4.37Å; L259-F293 HydrophobicContact CB-CE2 3.86Å; L259-F293 HydrophobicContact CB-CZ 4.11Å; L259-F293 HydrophobicContact CD2-CZ 4.45Å
260T97.6Very high95.9Very high0 Ų032.4 Ų32.40%016%0.16CC..Hα-helixtrans-59.2-46.4172.3-42.90000111.1N258 K262 M263 T264 Q287 E313N258-T260 VanDerWaalsContact C-N 3.3Å; N258-T260 PolarHBondContact O-N 2.97Å; T260-K262 PolarHBondContact O-N 2.84Å; T260-M263 WeakPolarHBondContact O-CB 3.02Å; T260-M263 PolarHBondContact O-N 2Å; T260-T264 PolarHBondContact O-N 3.35Å; T260-T264 PolarHBondContact O-OG1 3.34Å; T260-Q287 PolarHBondContact OG1-NE2 2.85Å; T260-Q287 VanDerWaalsContact OG1-NE2 3.12Å; T260-E313 VanDerWaalsContact CB-OE2 3.28Å; T260-E313 WeakPolarHBondContact CB-OE2 2.98Å; T260-E313 HydrophobicContact CG2-CG 3.79Å; T260-E313 PolarHBondContact OG1-OE2 2.85Å
261Q97.6Very high96.1Very high19 Ų1931.6 Ų31.69%0.08916%0.155CC..Hα-helixtrans-61.8-45.4177.7-70.765.730.500111.4N258 L259 M263 T264 Y265 S295 E313 W316N258-Q261 WeakPolarHBondContact O-CB 3.39Å; N258-Q261 PolarHBondContact O-N 3.46Å; N258-Q261 VanDerWaalsContact O-N 3.16Å; N258-Q261 PolarHBondContact O-OE1 3.26Å; L259-Q261 PolarHBondContact O-N 3.42Å; Q261-M263 VanDerWaalsContact C-N 3.3Å; Q261-M263 PolarHBondContact O-N 3.12Å; Q261-T264 PolarHBondContact O-N 3.36Å; Q261-Y265 HydrophobicContact CB-CE2 4.04Å; Q261-Y265 VanDerWaalsContact O-CD2 3.23Å; Q261-Y265 WeakPolarHBondContact O-CD2 3.35Å; Q261-Y265 VanDerWaalsContact O-CG 3.24Å; Q261-Y265 PolarHBondContact O-N 3.19Å; Q261-S295 PolarHBondContact NE2-OG 3.33Å; Q261-E313 VanDerWaalsContact NE2-CD 3.31Å; Q261-E313 PolarHBondContact NE2-OE1 3.45Å; Q261-E313 PolarHBondContact OE1-OE1 3.35Å; Q261-W316 HydrophobicContact CB-CH2 4.29Å; Q261-W316 HydrophobicContact CB-CZ3 4.5Å; Q261-W316 HydrophobicContact CG-CH2 3.78Å; Q261-W316 HydrophobicContact CG-CZ3 3.92Å
262K97.2Very high96.2Very high81 Ų8134.6 Ų34.635%0.35217%0.169SC..Hα-helixtrans-55.9-47.9175.6-70.4178.5179.8176.70110.3F163 E251 N258 L259 T260 T264 Y265 E266F163-K262 HydrophobicContact CE1-CB 4.23Å; F163-K262 HydrophobicContact CZ-CB 4.18Å; E251-K262 IonicContact OE2-NZ 2.7Å; E251-K262 PolarHBondContact OE2-NZ 2.94Å; E251-K262 VanDerWaalsContact OE2-NZ 3.16Å; N258-K262 PolarHBondContact O-N 2.95Å; L259-K262 HydrophobicContact CD1-CB 4.47Å; L259-K262 HydrophobicContact CD1-CD 4.34Å; L259-K262 PolarHBondContact O-N 3.36Å; T260-K262 PolarHBondContact O-N 2.84Å; K262-T264 PolarHBondContact O-N 2.75Å; K262-Y265 PolarHBondContact O-N 3.29Å; K262-E266 VanDerWaalsContact O-CG 3.24Å; K262-E266 WeakPolarHBondContact O-CG 3.03Å; K262-E266 PolarHBondContact O-N 3.05Å
263M98.4Very high96.4Very high2 Ų241.3 Ų41.31%0.0119%0.194CC..Hα-helixtrans-61.4-42.9176.7-70173.257.600112.6I135 F163 L259 T260 Q261 Y265 E266 A267 L283 Y285 L286I135-M263 HydrophobicContact CG2-CB 3.87Å; I135-M263 HydrophobicContact CG2-CE 4.43Å; I135-M263 HydrophobicContact CG2-CG 4.11Å; F163-M263 HydrophobicContact CD1-CG 4.41Å; F163-M263 HydrophobicContact CE1-CG 4.15Å; L259-M263 HydrophobicContact CG-SD 4.44Å; L259-M263 VanDerWaalsContact O-CG 3.31Å; L259-M263 WeakPolarHBondContact O-CG 3.35Å; L259-M263 PolarHBondContact O-N 3.38Å; T260-M263 WeakPolarHBondContact O-CB 3.02Å; T260-M263 PolarHBondContact O-N 2Å; Q261-M263 VanDerWaalsContact C-N 3.3Å; Q261-M263 PolarHBondContact O-N 3.12Å; M263-Y265 VanDerWaalsContact C-N 3.35Å; M263-Y265 PolarHBondContact O-N 2.96Å; M263-E266 PolarHBondContact O-N 3.49Å; M263-A267 WeakPolarHBondContact O-CB 3.05Å; M263-A267 PolarHBondContact O-N 3.29Å; M263-L283 HydrophobicContact CE-CD1 4.17Å; M263-Y285 HydrophobicContact CE-CD1 4.28Å; M263-L286 HydrophobicContact CE-CD1 4.19Å; M263-L286 HydrophobicContact SD-CD1 3.81Å
264T98.8Very high96.5Very high0 Ų040.1 Ų40.10%019%0.186CC..Hα-helixtrans-61.2-43.5176.2-53.10000111.3T260 Q261 K262 A267 V268 W316 S317 Q320T260-T264 PolarHBondContact O-N 3.35Å; T260-T264 PolarHBondContact O-OG1 3.34Å; Q261-T264 PolarHBondContact O-N 3.36Å; K262-T264 PolarHBondContact O-N 2.75Å; T264-A267 WeakPolarHBondContact O-CB 3.37Å; T264-A267 PolarHBondContact O-N 3.09Å; T264-V268 WeakPolarHBondContact O-CG2 3.5Å; T264-V268 PolarHBondContact O-N 2.93Å; T264-W316 HydrophobicContact CG2-CH2 4Å; T264-W316 HydrophobicContact CG2-CZ3 4.09Å; T264-W316 WeakPolarHBondContact OG1-CZ3 3.04Å; T264-S317 WeakPolarHBondContact OG1-CB 3.25Å; T264-S317 PolarHBondContact OG1-OG 3.36Å; T264-Q320 HydrophobicContact CG2-CB 3.61Å; T264-Q320 HydrophobicContact CG2-CG 3.94Å
265Y98.5Very high96.6Very high137 Ų13742.2 Ų42.254%0.53720%0.201SC..Hα-helixtrans-67.4-40.2178.9-62.4-33.1000112.6Q261 K262 M263 A267 V268 D269Q261-Y265 HydrophobicContact CB-CE2 4.04Å; Q261-Y265 VanDerWaalsContact O-CD2 3.23Å; Q261-Y265 WeakPolarHBondContact O-CD2 3.35Å; Q261-Y265 VanDerWaalsContact O-CG 3.24Å; Q261-Y265 PolarHBondContact O-N 3.19Å; K262-Y265 PolarHBondContact O-N 3.29Å; M263-Y265 VanDerWaalsContact C-N 3.35Å; M263-Y265 PolarHBondContact O-N 2.96Å; Y265-A267 VanDerWaalsContact C-N 3.27Å; Y265-A267 PolarHBondContact O-N 2.82Å; Y265-V268 PolarHBondContact O-N 2.03Å; Y265-D269 VanDerWaalsContact O-CB 3.32Å; Y265-D269 WeakPolarHBondContact O-CB 3.5Å; Y265-D269 PolarHBondContact O-N 3.23Å
266E98.6Very high96.7Very high26 Ų2643 Ų4312%0.12122%0.22CC..Hα-helixtrans-60.7-37.9172.6-70.1-73.4167.400111.7I135 Y161 F163 R245 K262 M263 F270I135-E266 VanDerWaalsContact CD1-C 3.42Å; I135-E266 HydrophobicContact CD1-CB 3.88Å; I135-E266 HydrophobicContact CG2-CB 4.31Å; Y161-E266 PolarHBondContact OH-OE2 3.23Å; F163-E266 HydrophobicContact CB-CG 4.32Å; F163-E266 HydrophobicContact CD1-CB 4.16Å; F163-E266 HydrophobicContact CD1-CG 3.65Å; F163-E266 HydrophobicContact CD2-CG 4.18Å; F163-E266 HydrophobicContact CE1-CG 3.92Å; F163-E266 HydrophobicContact CE2-CG 4.42Å; F163-E266 HydrophobicContact CG-CB 4.41Å; F163-E266 HydrophobicContact CG-CG 3.78Å; F163-E266 HydrophobicContact CZ-CG 4.29Å; R245-E266 IonicContact CZ-OE1 2.93Å; R245-E266 IonicContact NH1-OE1 3.68Å; R245-E266 PolarHBondContact NH1-OE1 2.75Å; R245-E266 IonicContact NH1-OE2 2.65Å; R245-E266 PolarHBondContact NH1-OE2 3.22Å; R245-E266 IonicContact NH2-OE1 3.83Å; R245-E266 PolarHBondContact NH2-OE1 3.2Å; K262-E266 VanDerWaalsContact O-CG 3.24Å; K262-E266 WeakPolarHBondContact O-CG 3.03Å; K262-E266 PolarHBondContact O-N 3.05Å; M263-E266 PolarHBondContact O-N 3.49Å; E266-F270 WeakPolarHBondContact O-CB 3.39Å; E266-F270 PolarHBondContact O-N 2.84Å
267A98.9Very high96.9Very high0 Ų050.5 Ų50.50%025%0.248CC..Hα-helixtrans-69.4-45.3176.700000112.3I135 M263 T264 Y265 F270 I271 L281 L283 I321I135-A267 HydrophobicContact CD1-CB 3.82Å; I135-A267 VanDerWaalsContact CD1-N 3.3Å; M263-A267 WeakPolarHBondContact O-CB 3.05Å; M263-A267 PolarHBondContact O-N 3.29Å; T264-A267 WeakPolarHBondContact O-CB 3.37Å; T264-A267 PolarHBondContact O-N 3.09Å; Y265-A267 VanDerWaalsContact C-N 3.27Å; Y265-A267 PolarHBondContact O-N 2.82Å; A267-F270 PolarHBondContact O-N 3.35Å; A267-I271 WeakPolarHBondContact O-CD1 3.42Å; A267-I271 VanDerWaalsContact O-CG1 3.24Å; A267-I271 WeakPolarHBondContact O-CG1 3.43Å; A267-I271 PolarHBondContact O-N 3.32Å; A267-L281 HydrophobicContact CB-CD2 3.89Å; A267-L283 HydrophobicContact CB-CD1 4.3Å; A267-L283 HydrophobicContact CB-CD2 4.22Å; A267-I321 HydrophobicContact CB-CD1 3.68Å
268V98.9Very high97.4Very high21 Ų2147.1 Ų47.113%0.12724%0.235CC..Hα-helixtrans-60.7-48.9176168.40000110.6T264 Y265 F270 I271 E272 I321 T324T264-V268 WeakPolarHBondContact O-CG2 3.5Å; T264-V268 PolarHBondContact O-N 2.93Å; Y265-V268 PolarHBondContact O-N 2.03Å; V268-F270 VanDerWaalsContact C-N 3.34Å; V268-F270 PolarHBondContact O-N 3.2Å; V268-I271 PolarHBondContact O-N 3.49Å; V268-I271 VanDerWaalsContact O-N 3.15Å; V268-E272 HydrophobicContact CG1-CG 4.4Å; V268-E272 WeakPolarHBondContact O-CG 3.26Å; V268-E272 PolarHBondContact O-N 2.66Å; V268-I321 HydrophobicContact CG2-CD1 4.18Å; V268-T324 HydrophobicContact CG1-CG2 4.14Å
269D98.8Very high97.7Very high62 Ų6243.8 Ų43.833%0.33222%0.218SC..Hα-helixtrans-61.4-41.1178.3171.173.3000111.9Y265 I271 E272 R273Y265-D269 VanDerWaalsContact O-CB 3.32Å; Y265-D269 WeakPolarHBondContact O-CB 3.5Å; Y265-D269 PolarHBondContact O-N 3.23Å; D269-I271 PolarHBondContact O-N 3.32Å; D269-E272 PolarHBondContact O-N 3.23Å; D269-R273 WeakPolarHBondContact O-CB 3.3Å; D269-R273 WeakPolarHBondContact O-CG 3.32Å; D269-R273 PolarHBondContact O-N 3.31Å; D269-R273 IonicContact OD1-NE 3.59Å; D269-R273 IonicContact OD2-CZ 2.61Å; D269-R273 IonicContact OD2-NE 2.74Å; D269-R273 PolarHBondContact OD2-NE 3.08Å; D269-R273 IonicContact OD2-NH2 3.01Å; D269-R273 PolarHBondContact OD2-NH2 3.15Å
270F98.8Very high97.9Very high7 Ų743.8 Ų43.83%0.03122%0.217CC..Hα-helixtrans-60.1-45.5173.1176.6-99.4000111.9N131 A133 E266 A267 V268 N274 F279 L281N131-F270 HydrophobicContact CB-CZ 4.45Å; A133-F270 HydrophobicContact CB-CD1 3.91Å; A133-F270 HydrophobicContact CB-CD2 3.56Å; A133-F270 HydrophobicContact CB-CE1 3.78Å; A133-F270 HydrophobicContact CB-CE2 3.43Å; A133-F270 VanDerWaalsContact CB-CE2 3.43Å; A133-F270 HydrophobicContact CB-CG 3.79Å; A133-F270 HydrophobicContact CB-CZ 3.54Å; E266-F270 WeakPolarHBondContact O-CB 3.39Å; E266-F270 PolarHBondContact O-N 2.84Å; A267-F270 PolarHBondContact O-N 3.35Å; V268-F270 VanDerWaalsContact C-N 3.34Å; V268-F270 PolarHBondContact O-N 3.2Å; F270-N274 VanDerWaalsContact CD2-ND2 3.28Å; F270-N274 WeakPolarHBondContact CD2-ND2 3.2Å; F270-N274 WeakPolarHBondContact CE2-ND2 3.28Å; F270-N274 WeakPolarHBondContact O-CB 3.27Å; F270-N274 PolarHBondContact O-N 3.18Å; F270-N274 PolarHBondContact O-ND2 2.86Å; F270-F279 HydrophobicContact CE1-CB 3.94Å; F270-F279 AromaticContact CE1-CD2 3.94Å; F270-F279 HydrophobicContact CE1-CD2 3.94Å; F270-F279 HydrophobicContact CE1-CG 4.18Å; F270-F279 HydrophobicContact CZ-CB 4.04Å; F270-L281 HydrophobicContact CD1-CB 4.06Å; F270-L281 HydrophobicContact CD1-CD1 4.15Å; F270-L281 HydrophobicContact CD1-CG 4.49Å; F270-L281 HydrophobicContact CE1-CB 3.95Å
271I98.8Very high98Very high0 Ų043.8 Ų43.80%022%0.217CC..Hα-helixtrans-63.1-44.2178.5-65.6162.1000110.5I33 A267 V268 D269 N274 S275 F279 L281 I321 T324 L325 L328I33-I271 HydrophobicContact CD1-CD1 3.73Å; I33-I271 HydrophobicContact CD1-CG1 4.21Å; A267-I271 WeakPolarHBondContact O-CD1 3.42Å; A267-I271 VanDerWaalsContact O-CG1 3.24Å; A267-I271 WeakPolarHBondContact O-CG1 3.43Å; A267-I271 PolarHBondContact O-N 3.32Å; V268-I271 PolarHBondContact O-N 3.49Å; V268-I271 VanDerWaalsContact O-N 3.15Å; D269-I271 PolarHBondContact O-N 3.32Å; I271-N274 CarbonylContact O-C 3.48Å; I271-N274 PolarHBondContact O-N 3.09Å; I271-S275 PolarHBondContact O-N 2.9Å; I271-F279 HydrophobicContact CG1-CE2 4.16Å; I271-F279 HydrophobicContact CG1-CZ 4.26Å; I271-F279 HydrophobicContact CG2-CE1 4.4Å; I271-F279 HydrophobicContact CG2-CZ 3.97Å; I271-L281 HydrophobicContact CD1-CD2 3.95Å; I271-L281 HydrophobicContact CG1-CD2 4.08Å; I271-I321 HydrophobicContact CD1-CD1 3.99Å; I271-I321 HydrophobicContact CD1-CG2 3.98Å; I271-T324 HydrophobicContact CB-CG2 4.25Å; I271-T324 HydrophobicContact CG2-CG2 3.93Å; I271-L325 HydrophobicContact CG2-CD2 4.11Å; I271-L328 HydrophobicContact CG2-CD1 3.73Å
272E98.6Very high98Very high77 Ų7743 Ų4336%0.3621%0.214SC..Hα-helixtrans-61.5-46.5179.5-73.8-174.1140.600112.7V268 D269 N274 T324 R327 L328V268-E272 HydrophobicContact CG1-CG 4.4Å; V268-E272 WeakPolarHBondContact O-CG 3.26Å; V268-E272 PolarHBondContact O-N 2.66Å; D269-E272 PolarHBondContact O-N 3.23Å; E272-N274 PolarHBondContact O-N 2.74Å; E272-T324 HydrophobicContact CG-CG2 4.44Å; E272-R327 IonicContact OE1-CZ 3.13Å; E272-R327 IonicContact OE1-NH1 2.77Å; E272-R327 PolarHBondContact OE1-NH1 2.75Å; E272-R327 IonicContact OE1-NH2 2.65Å; E272-R327 PolarHBondContact OE1-NH2 3.4Å; E272-L328 HydrophobicContact CG-CD1 4.04Å
273R98.1Very high98.1Very high144 Ų14439.1 Ų39.154%0.54320%0.197SC..Hα-helixtrans-64.5-21.6178.4-72.5-173-72.4155.3-5.3113.2D269D269-R273 WeakPolarHBondContact O-CB 3.3Å; D269-R273 WeakPolarHBondContact O-CG 3.32Å; D269-R273 PolarHBondContact O-N 3.31Å; D269-R273 IonicContact OD1-NE 3.59Å; D269-R273 IonicContact OD2-CZ 2.61Å; D269-R273 IonicContact OD2-NE 2.74Å; D269-R273 PolarHBondContact OD2-NE 3.08Å; D269-R273 IonicContact OD2-NH2 3.01Å; D269-R273 PolarHBondContact OD2-NH2 3.15Å
274N98Very high98.1Very high15 Ų1539 Ų398%0.0820%0.196CC..Hα-helixtrans-113.14.1-173.1-67.2-68.6000114.2N131 F270 I271 E272 G276 R277 F279N131-N274 WeakPolarHBondContact CB-OD1 3.34Å; N131-N274 PolarHBondContact ND2-OD1 3.32Å; F270-N274 VanDerWaalsContact CD2-ND2 3.28Å; F270-N274 WeakPolarHBondContact CD2-ND2 3.2Å; F270-N274 WeakPolarHBondContact CE2-ND2 3.28Å; F270-N274 WeakPolarHBondContact O-CB 3.27Å; F270-N274 PolarHBondContact O-N 3.18Å; F270-N274 PolarHBondContact O-ND2 2.86Å; I271-N274 CarbonylContact O-C 3.48Å; I271-N274 PolarHBondContact O-N 3.09Å; E272-N274 PolarHBondContact O-N 2.74Å; N274-G276 PolarHBondContact O-N 3.18Å; N274-R277 PolarHBondContact O-N 3.09Å; N274-F279 HydrophobicContact CB-CB 3.98Å; N274-F279 HydrophobicContact CB-CD1 3.91Å; N274-F279 HydrophobicContact CB-CG 4.19Å
275S95.3Very high98.1Very high50 Ų5039 Ų3935%0.3520%0.196SC..THydrogen-bonded Turntrans-58.9-20.1-173.672.10000114.9I271I271-S275 PolarHBondContact O-N 2.9Å
276G94.7Very high98.1Very high75 Ų7532.6 Ų32.677%0.77317%0.171SC*.THydrogen-bonded Turntrans-93.74.7175.800000115.6N274N274-G276 PolarHBondContact O-N 3.18Å
277R95Very high97.9Very high169 Ų16931.4 Ų31.464%0.63817%0.166SC*.SBendtrans-140.9153.8-178.8-65.5-174.8-176.8179.23.1110.4N31 N274 F279N31-R277 PolarHBondContact OD1-O 3.32Å; N274-R277 PolarHBondContact O-N 3.09Å; R277-F279 PolarHBondContact O-N 3.49Å
278P97.8Very high97.6Very high34 Ų3431.7 Ų31.722%0.22117%0.167CC..  trans-62.7132.4173.626.9-34.2000110.4K29 N31 Y130 N131K29-P278 HydrophobicContact CB-CB 3.91Å; K29-P278 HydrophobicContact CB-CG 4.29Å; N31-P278 WeakPolarHBondContact OD1-CA 3.19Å; Y130-P278 WeakPolarHBondContact CA-O 3.28Å; Y130-P278 HydrophobicContact CD1-CB 3.87Å; Y130-P278 HydrophobicContact CD2-CB 4.29Å; Y130-P278 HydrophobicContact CE1-CB 3.7Å; Y130-P278 HydrophobicContact CE2-CB 4.16Å; Y130-P278 HydrophobicContact CG-CB 4.15Å; N131-P278 PolarHBondContact N-O 2.67Å; N131-P278 VanDerWaalsContact N-O 3.13Å
279F98.8Very high97.3Very high0 Ų031.4 Ų31.40%017%0.165CC..EExtended strand (participates in β ladder)trans-132.1153.7178.764.6-99.5000112.9N31 F32 I33 N131 F270 I271 N274 R277 L325N31-F279 CarbonylContact C-O 3.51Å; N31-F279 WeakPolarHBondContact CA-O 3.28Å; N31-F279 HydrophobicContact CB-CD1 4.11Å; N31-F279 HydrophobicContact CB-CD2 4.13Å; N31-F279 HydrophobicContact CB-CE1 3.79Å; N31-F279 HydrophobicContact CB-CE2 3.8Å; N31-F279 HydrophobicContact CB-CG 4.27Å; N31-F279 HydrophobicContact CB-CZ 3.62Å; N31-F279 WeakPolarHBondContact ND2-CE1 3.31Å; N31-F279 VanDerWaalsContact OD1-CD1 3.27Å; N31-F279 WeakPolarHBondContact OD1-CD1 3.16Å; N31-F279 WeakPolarHBondContact OD1-CE1 3.4Å; N31-F279 PolarHBondContact OD1-N 2.98Å; F32-F279 PolarHBondContact N-O 3.5Å; I33-F279 HydrophobicContact CD1-CE2 3.97Å; I33-F279 HydrophobicContact CD1-CZ 4.39Å; I33-F279 HydrophobicContact CG1-CE2 3.76Å; N131-F279 CarbonylContact O-C 3.54Å; N131-F279 VanDerWaalsContact O-CA 3.23Å; N131-F279 WeakPolarHBondContact O-CA 3.34Å; F270-F279 HydrophobicContact CE1-CB 3.94Å; F270-F279 AromaticContact CE1-CD2 3.94Å; F270-F279 HydrophobicContact CE1-CD2 3.94Å; F270-F279 HydrophobicContact CE1-CG 4.18Å; F270-F279 HydrophobicContact CZ-CB 4.04Å; I271-F279 HydrophobicContact CG1-CE2 4.16Å; I271-F279 HydrophobicContact CG1-CZ 4.26Å; I271-F279 HydrophobicContact CG2-CE1 4.4Å; I271-F279 HydrophobicContact CG2-CZ 3.97Å; N274-F279 HydrophobicContact CB-CB 3.98Å; N274-F279 HydrophobicContact CB-CD1 3.91Å; N274-F279 HydrophobicContact CB-CG 4.19Å; R277-F279 PolarHBondContact O-N 3.49Å; F279-L325 HydrophobicContact CZ-CD2 4.43Å
280L98.9Very high96.7Very high0 Ų028.9 Ų28.90%015%0.152CC..EExtended strand (participates in β ladder)trans-118.8119.9167-179.3148.3000108.5F32 L34 F121 V125 Y130 N131 T132 A133 F159 F282 I406F32-L280 HydrophobicContact CB-CB 4.31Å; F32-L280 HydrophobicContact CB-CD1 4.19Å; F32-L280 HydrophobicContact CB-CG 4.08Å; F32-L280 HydrophobicContact CD2-CB 4.39Å; F32-L280 HydrophobicContact CD2-CD1 4.18Å; F32-L280 CarbonylContact O-C 3.42Å; F32-L280 WeakPolarHBondContact O-CA 3.19Å; L34-L280 HydrophobicContact CD1-CD1 4.38Å; F121-L280 HydrophobicContact CD2-CD1 3.59Å; F121-L280 HydrophobicContact CE2-CD1 3.75Å; F121-L280 HydrophobicContact CE2-CD2 4.05Å; V125-L280 HydrophobicContact CG2-CB 4.11Å; V125-L280 HydrophobicContact CG2-CD1 3.75Å; Y130-L280 HydrophobicContact CD1-CB 4.48Å; N131-L280 PolarHBondContact O-N 2.95Å; T132-L280 CarbonylContact C-O 3.57Å; T132-L280 VanDerWaalsContact CA-O 3.32Å; T132-L280 WeakPolarHBondContact CA-O 3.48Å; T132-L280 HydrophobicContact CG2-CB 4.15Å; A133-L280 PolarHBondContact N-O 3.4Å; F159-L280 HydrophobicContact CE1-CD2 3.8Å; L280-F282 HydrophobicContact CD2-CB 4.41Å; L280-I406 HydrophobicContact CD1-CD1 4.5Å; L280-I406 HydrophobicContact CD1-CG2 4.22Å
281L98.9Very high96.3Very high0 Ų028.6 Ų28.60%015%0.15CC..EExtended strand (participates in β ladder)trans-111.1118.8170.5171.161.6000108.8F32 I33 L34 A133 I135 A267 F270 I271 L283F32-L281 PolarHBondContact O-N 3.01Å; I33-L281 CarbonylContact C-O 3.39Å; I33-L281 WeakPolarHBondContact CA-O 3.07Å; I33-L281 HydrophobicContact CG1-CB 4.18Å; I33-L281 HydrophobicContact CG1-CD2 4.43Å; I33-L281 HydrophobicContact CG2-CD2 4.2Å; L34-L281 PolarHBondContact N-O 3.21Å; A133-L281 HydrophobicContact CB-CD1 4.08Å; I135-L281 HydrophobicContact CB-CD1 4.45Å; I135-L281 HydrophobicContact CD1-CD1 3.68Å; I135-L281 HydrophobicContact CG1-CD1 3.96Å; A267-L281 HydrophobicContact CB-CD2 3.89Å; F270-L281 HydrophobicContact CD1-CB 4.06Å; F270-L281 HydrophobicContact CD1-CD1 4.15Å; F270-L281 HydrophobicContact CD1-CG 4.49Å; F270-L281 HydrophobicContact CE1-CB 3.95Å; I271-L281 HydrophobicContact CD1-CD2 3.95Å; I271-L281 HydrophobicContact CG1-CD2 4.08Å; L281-L283 HydrophobicContact CG-CB 4.4Å
282F98.9Very high95.9Very high3 Ų328.8 Ų28.81%0.01315%0.151CC..EExtended strand (participates in β ladder)trans-99.9101.1165.1-177-158.3000108.9L34 M36 F85 L86 A133 L134 I135 F159 L280 S284L34-F282 HydrophobicContact CB-CD2 4.01Å; L34-F282 CarbonylContact O-C 3.31Å; M36-F282 HydrophobicContact CB-CE2 3.66Å; M36-F282 HydrophobicContact CB-CZ 4.23Å; M36-F282 HydrophobicContact CE-CZ 4.48Å; M36-F282 HydrophobicContact SD-CE2 4.28Å; M36-F282 HydrophobicContact SD-CZ 3.95Å; F85-F282 HydrophobicContact CD1-CE1 4.27Å; F85-F282 HydrophobicContact CD1-CE2 4.32Å; F85-F282 AromaticContact CD1-CZ 3.89Å; F85-F282 HydrophobicContact CD1-CZ 3.89Å; F85-F282 HydrophobicContact CE1-CD1 4.45Å; F85-F282 HydrophobicContact CE1-CD2 4.09Å; F85-F282 HydrophobicContact CE1-CE1 4.05Å; F85-F282 AromaticContact CE1-CE2 3.61Å; F85-F282 HydrophobicContact CE1-CE2 3.61Å; F85-F282 AromaticContact CE1-CZ 3.61Å; F85-F282 HydrophobicContact CE1-CZ 3.61Å; F85-F282 HydrophobicContact CZ-CE2 4.37Å; L86-F282 HydrophobicContact CD2-CD1 4.06Å; L86-F282 HydrophobicContact CD2-CE1 3.97Å; A133-F282 PolarHBondContact O-N 3.09Å; L134-F282 WeakPolarHBondContact CA-O 3.16Å; L134-F282 HydrophobicContact CD1-CB 4.11Å; L134-F282 HydrophobicContact CD1-CD1 3.38Å; L134-F282 HydrophobicContact CD1-CE1 3.88Å; L134-F282 HydrophobicContact CD1-CG 3.84Å; I135-F282 PolarHBondContact N-O 3.47Å; F159-F282 HydrophobicContact CE1-CB 3.91Å; F159-F282 HydrophobicContact CE1-CD1 4.5Å; F159-F282 HydrophobicContact CZ-CB 4.18Å; F159-F282 AromaticContact CZ-CD1 3.95Å; F159-F282 HydrophobicContact CZ-CD1 3.95Å; L280-F282 HydrophobicContact CD2-CB 4.41Å; F282-S284 PolarHBondContact O-N 2.83Å
283L98.9Very high95.6Very high0 Ų025.6 Ų25.60%014%0.136CC..EExtended strand (participates in β ladder)trans-9394.1175-175.556000109L34 M35 M36 I135 M263 A267 L281 Y285 I321L34-L283 PolarHBondContact O-N 2.84Å; M35-L283 WeakPolarHBondContact CA-O 3.24Å; M35-L283 HydrophobicContact CG-CB 4.31Å; M35-L283 HydrophobicContact CG-CD2 4.47Å; M36-L283 PolarHBondContact N-O 3.09Å; I135-L283 HydrophobicContact CB-CD1 3.84Å; I135-L283 HydrophobicContact CG2-CD1 3.71Å; M263-L283 HydrophobicContact CE-CD1 4.17Å; A267-L283 HydrophobicContact CB-CD1 4.3Å; A267-L283 HydrophobicContact CB-CD2 4.22Å; L281-L283 HydrophobicContact CG-CB 4.4Å; L283-Y285 HydrophobicContact CD1-CE1 4.39Å; L283-Y285 HydrophobicContact CD2-CE1 3.97Å; L283-Y285 HydrophobicContact CD2-CE2 4.07Å; L283-Y285 VanDerWaalsContact CD2-CZ 3.47Å; L283-Y285 WeakPolarHBondContact CD2-OH 3.23Å; L283-Y285 HydrophobicContact CG-CE1 4.03Å; L283-Y285 HydrophobicContact CG-CE2 3.98Å; L283-I321 HydrophobicContact CD2-CD1 4.4Å; L283-I321 HydrophobicContact CD2-CG1 4.23Å
284S98.8Very high95.4Very high0 Ų019 Ų190%011%0.112CC..EExtended strand (participates in β ladder)trans-98.692.8-179.6171.80000110.1M36 R82 I135 G136 K137 F282M36-S284 CarbonylContact O-C 3.53Å; M36-S284 WeakPolarHBondContact O-CA 3.31Å; R82-S284 PolarHBondContact NH1-OG 3.08Å; I135-S284 PolarHBondContact O-N 2.87Å; G136-S284 CarbonylContact C-O 3.25Å; G136-S284 VanDerWaalsContact CA-O 3.24Å; G136-S284 WeakPolarHBondContact CA-O 3.26Å; K137-S284 PolarHBondContact N-O 2.98Å; K137-S284 WeakPolarHBondContact O-CB 3.23Å; K137-S284 PolarHBondContact O-OG 3.29Å; F282-S284 PolarHBondContact O-N 2.83Å
285Y98.6Very high95.3Very high0 Ų018.4 Ų18.40%011%0.11CC..  trans-56.5148.1179.3-63.3-77.2000112.4M35 M36 L37 M263 L283 V314 S317M35-Y285 HydrophobicContact CB-CE2 4.26Å; M35-Y285 HydrophobicContact CG-CE2 4.46Å; M36-Y285 PolarHBondContact O-N 2.96Å; L37-Y285 HydrophobicContact CD1-CD2 4.45Å; L37-Y285 HydrophobicContact CG-CD2 4.16Å; M263-Y285 HydrophobicContact CE-CD1 4.28Å; L283-Y285 HydrophobicContact CD1-CE1 4.39Å; L283-Y285 HydrophobicContact CD2-CE1 3.97Å; L283-Y285 HydrophobicContact CD2-CE2 4.07Å; L283-Y285 VanDerWaalsContact CD2-CZ 3.47Å; L283-Y285 WeakPolarHBondContact CD2-OH 3.23Å; L283-Y285 HydrophobicContact CG-CE1 4.03Å; L283-Y285 HydrophobicContact CG-CE2 3.98Å; Y285-V314 HydrophobicContact CD1-CG1 4.41Å; Y285-V314 HydrophobicContact CD1-CG2 4.25Å; Y285-V314 HydrophobicContact CD2-CG1 4Å; Y285-V314 HydrophobicContact CE1-CG1 4.27Å; Y285-V314 HydrophobicContact CE2-CG1 3.83Å; Y285-V314 HydrophobicContact CG-CG1 4.27Å; Y285-V314 HydrophobicContact CG-CG2 4.34Å; Y285-S317 WeakPolarHBondContact CE1-OG 3.03Å; Y285-S317 WeakPolarHBondContact OH-CB 3.36Å; Y285-S317 PolarHBondContact OH-OG 2.77Å
286L97.1Very high95.3Very high1 Ų119.6 Ų19.61%0.00512%0.123CC..  trans-76-19.7163.1-83.259.4000110.4K137 I165 N169 L256 L259 M263 H289 F293K137-L286 HydrophobicContact CB-CD1 4.14Å; I165-L286 HydrophobicContact CD1-CD1 4.04Å; I165-L286 HydrophobicContact CD1-CD2 3.78Å; I165-L286 HydrophobicContact CD1-CG 3.69Å; I165-L286 HydrophobicContact CG1-CD1 4.05Å; I165-L286 HydrophobicContact CG1-CD2 4.44Å; I165-L286 HydrophobicContact CG1-CG 4.26Å; I165-L286 HydrophobicContact CG2-CD2 4.47Å; N169-L286 HydrophobicContact CB-CB 4.45Å; N169-L286 HydrophobicContact CB-CD2 4.46Å; N169-L286 HydrophobicContact CB-CG 4.41Å; L256-L286 HydrophobicContact CD2-CD2 4.31Å; L259-L286 HydrophobicContact CD2-CD2 3.44Å; L259-L286 VanDerWaalsContact CD2-CD2 3.44Å; L259-L286 HydrophobicContact CG-CD2 4.37Å; M263-L286 HydrophobicContact CE-CD1 4.19Å; M263-L286 HydrophobicContact SD-CD1 3.81Å; L286-H289 WeakPolarHBondContact O-CB 3.37Å; L286-H289 PolarHBondContact O-N 3.39Å; L286-H289 VanDerWaalsContact O-N 3.15Å; L286-F293 HydrophobicContact CB-CE1 4.28Å; L286-F293 HydrophobicContact CB-CZ 4.34Å; L286-F293 HydrophobicContact CD2-CZ 4.4Å
287Q94.6Very high95.4Very high2 Ų219.7 Ų19.71%0.00912%0.116CC..THydrogen-bonded Turntrans-82.8139.2-177.4-9265.1-2.500109.3L37 D38 T260 F293 A310 V314L37-Q287 WeakPolarHBondContact CA-O 3.17Å; D38-Q287 PolarHBondContact N-O 3.23Å; D38-Q287 CarbonylContact O-C 3.57Å; T260-Q287 PolarHBondContact OG1-NE2 2.85Å; T260-Q287 VanDerWaalsContact OG1-NE2 3.12Å; Q287-F293 VanDerWaalsContact CD-CZ 3.41Å; Q287-F293 VanDerWaalsContact NE2-CD2 3.29Å; Q287-F293 PolarHBondContact NE2-O 3.45Å; Q287-A310 HydrophobicContact CG-CB 3.95Å; Q287-V314 HydrophobicContact CB-CG2 3.34Å; Q287-V314 HydrophobicContact CG-CG2 3.92Å
288V93.3Very high95.5Very high5 Ų513.3 Ų13.33%0.039%0.093CC..THydrogen-bonded Turncis-109.938.37.8-74.50000112.1D38 L40 L292 Y307 A310 V311D38-V288 CarbonylContact O-C 3.49Å; D38-V288 VanDerWaalsContact O-C 3.31Å; D38-V288 WeakPolarHBondContact O-CA 3.28Å; D38-V288 PolarHBondContact O-N 2.92Å; L40-V288 HydrophobicContact CB-CG2 4.19Å; L40-V288 HydrophobicContact CD1-CG2 4.16Å; V288-L292 HydrophobicContact CB-CD2 4.41Å; V288-L292 WeakPolarHBondContact O-CD2 3.11Å; V288-Y307 HydrophobicContact CB-CD2 4.13Å; V288-Y307 HydrophobicContact CB-CE2 3.64Å; V288-Y307 HydrophobicContact CG1-CE2 4.48Å; V288-Y307 HydrophobicContact CG2-CD2 4.3Å; V288-Y307 HydrophobicContact CG2-CE2 3.34Å; V288-Y307 WeakPolarHBondContact CG2-OH 3.36Å; V288-A310 HydrophobicContact CG1-CB 3.85Å; V288-V311 HydrophobicContact CG1-CG2 3.64Å; V288-V311 HydrophobicContact CG2-CG2 4.5Å
289H93.1Very high95.4Very high16 Ų1617.4 Ų17.47%0.07411%0.107CC..SBendtrans-74.5147.9178.7-168.8-73.9000112D38 D39 N169 L286 K367D38-H289 HydrophobicContact CB-CB 3.8Å; D38-H289 PolarHBondContact O-N 3.48Å; D38-H289 IonicContact OD1-CD2 3.23Å; D38-H289 PolarHBondContact OD1-CD2 2.74Å; D38-H289 WeakPolarHBondContact OD2-CB 3.27Å; D38-H289 IonicContact OD2-CD2 2.74Å; D38-H289 IonicContact OD2-CG 3.72Å; D39-H289 IonicContact OD1-CD2 3.77Å; D39-H289 IonicContact OD2-CD2 3.36Å; D39-H289 PolarHBondContact OD2-CD2 3.29Å; D39-H289 IonicContact OD2-CG 3.04Å; D39-H289 IonicContact OD2-NE2 2.73Å; N169-H289 PolarHBondContact ND2-O 3.16Å; N169-H289 PolarHBondContact O-CE1 3.19Å; N169-H289 PolarHBondContact O-ND1 2.85Å; L286-H289 WeakPolarHBondContact O-CB 3.37Å; L286-H289 PolarHBondContact O-N 3.39Å; L286-H289 VanDerWaalsContact O-N 3.15Å; H289-K367 PolarHBondContact CD2-NZ 3.26Å; H289-K367 VanDerWaalsContact CD2-NZ 3.26Å; H289-K367 PolarHBondContact NE2-NZ 2.65Å
290T86.9Confident95.1Very high9 Ų920.7 Ų20.76%0.05514%0.141CC..SBendtrans-65143.3175.7-166.90000112.4N169 R171 E348N169-T290 CarbonylContact C-O 3.54Å; N169-T290 VanDerWaalsContact C-O 3.25Å; R171-T290 HydrophobicContact CG-CG2 3.96Å; R171-T290 VanDerWaalsContact CG-OG1 3.32Å; R171-T290 WeakPolarHBondContact CG-OG1 3.08Å; T290-E348 WeakPolarHBondContact CB-OE1 3.41Å; T290-E348 WeakPolarHBondContact CG2-OE1 3.19Å; T290-E348 PolarHBondContact OG1-OE1 2.95Å
291A88.9Confident95Very high0 Ų023.9 Ų23.90%016%0.161CC..SBendcis-70.1129.3-2.500000112.5N169 Q174 H177 L256 F293N169-A291 PolarHBondContact ND2-N 2.95Å; N169-A291 PolarHBondContact ND2-O 3.14Å; Q174-A291 HydrophobicContact CB-CB 3.31Å; Q174-A291 HydrophobicContact CG-CB 4.21Å; H177-A291 HydrophobicContact CB-CB 3.97Å; L256-A291 HydrophobicContact CD1-CB 4.34Å; A291-F293 WeakPolarHBondContact O-CD1 3.07Å
292L89.9Confident94.7Very high5 Ų524.7 Ų24.73%0.02617%0.166CC..PPolyproline II helixtrans-68.2135179-65.6173.6000111.6Q174 V288 V306 Y307 H356Q174-L292 PolarHBondContact NE2-O 3.48Å; Q174-L292 PolarHBondContact OE1-O 3.16Å; V288-L292 HydrophobicContact CB-CD2 4.41Å; V288-L292 WeakPolarHBondContact O-CD2 3.11Å; L292-V306 HydrophobicContact CB-CB 4.28Å; L292-V306 HydrophobicContact CB-CG1 3.81Å; L292-Y307 HydrophobicContact CD1-CD2 4.29Å; L292-Y307 HydrophobicContact CD2-CD2 4.04Å; L292-H356 HydrophobicContact CD1-CB 3.8Å; L292-H356 WeakPolarHBondContact CD1-O 3.36Å
293F92.9Very high94.3Very high9 Ų929.2 Ų29.24%0.03920%0.199CC..  trans-146.7154.7176.668.9-81000111.2L256 L259 L286 Q287 A291 A310L256-F293 HydrophobicContact CB-CB 4.08Å; L256-F293 HydrophobicContact CB-CD1 4Å; L256-F293 HydrophobicContact CB-CD2 3.92Å; L256-F293 HydrophobicContact CB-CE1 4.36Å; L256-F293 HydrophobicContact CB-CE2 4.24Å; L256-F293 HydrophobicContact CB-CG 3.75Å; L256-F293 HydrophobicContact CB-CZ 4.43Å; L256-F293 HydrophobicContact CD1-CD1 3.92Å; L256-F293 HydrophobicContact CD1-CE1 4.39Å; L256-F293 HydrophobicContact CD1-CG 4.35Å; L256-F293 HydrophobicContact CD2-CD1 3.83Å; L256-F293 HydrophobicContact CD2-CE1 3.49Å; L256-F293 VanDerWaalsContact CD2-CE1 3.49Å; L256-F293 HydrophobicContact CD2-CE2 4.34Å; L256-F293 HydrophobicContact CD2-CG 4.4Å; L256-F293 HydrophobicContact CD2-CZ 3.72Å; L256-F293 HydrophobicContact CG-CD1 4.13Å; L256-F293 HydrophobicContact CG-CE1 4.29Å; L256-F293 HydrophobicContact CG-CG 4.39Å; L256-F293 WeakPolarHBondContact O-CD2 3.44Å; L256-F293 WeakPolarHBondContact O-CE2 3.16Å; L259-F293 HydrophobicContact CB-CE2 3.86Å; L259-F293 HydrophobicContact CB-CZ 4.11Å; L259-F293 HydrophobicContact CD2-CZ 4.45Å; L286-F293 HydrophobicContact CB-CE1 4.28Å; L286-F293 HydrophobicContact CB-CZ 4.34Å; L286-F293 HydrophobicContact CD2-CZ 4.4Å; Q287-F293 VanDerWaalsContact CD-CZ 3.41Å; Q287-F293 VanDerWaalsContact NE2-CD2 3.29Å; Q287-F293 PolarHBondContact NE2-O 3.45Å; A291-F293 WeakPolarHBondContact O-CD1 3.07Å; F293-A310 WeakPolarHBondContact O-CB 3.44Å
294A94.4Very high93.9Very high5 Ų533.2 Ų33.24%0.04122%0.217CC..  trans-148.6149.5171.800000107.7F298 K299 D309A294-F298 HydrophobicContact CB-CB 4.16Å; A294-K299 HydrophobicContact CB-CG 4.5Å; A294-K299 WeakPolarHBondContact O-CE 3.24Å; A294-D309 HydrophobicContact CB-CB 3.74Å
295S95.4Very high93.5Very high4 Ų434.9 Ų34.93%0.02823%0.234CC..  trans-66.7166.8173.567.40000111.8N258 Q261 A297 F298 K299 E313N258-S295 WeakPolarHBondContact OD1-CB 3.33Å; Q261-S295 PolarHBondContact NE2-OG 3.33Å; S295-A297 PolarHBondContact O-N 2.73Å; S295-A297 VanDerWaalsContact O-N 3.08Å; S295-F298 PolarHBondContact O-N 3.32Å; S295-F298 WeakPolarHBondContact OG-CD2 3.18Å; S295-K299 WeakPolarHBondContact O-CG 3.47Å; S295-K299 PolarHBondContact O-N 3.04Å; S295-K299 VanDerWaalsContact O-N 3.13Å; S295-E313 WeakPolarHBondContact CA-OE1 3.35Å; S295-E313 WeakPolarHBondContact CB-OE1 3.15Å; S295-E313 PolarHBondContact N-OE1 3.18Å; S295-E313 PolarHBondContact OG-OE1 3.04Å
296A96.1Very high93.2Very high75 Ų7537.4 Ų37.462%0.6225%0.249SC*.THydrogen-bonded Turntrans-54.6-29.2178.900000113.8F298A296-F298 VanDerWaalsContact C-N 3.31Å; A296-F298 PolarHBondContact O-N 2.61Å
297A96.3Very high93.1Very high77 Ų7737.9 Ų37.964%0.63625%0.251SS*.THydrogen-bonded Turntrans-71-24.7179.800000113.6S295S295-A297 PolarHBondContact O-N 2.73Å; S295-A297 VanDerWaalsContact O-N 3.08Å
298F96.6Very high93.1Very high34 Ų3437.8 Ų37.815%0.14925%0.251CS..THydrogen-bonded Turntrans-109.6-15.6-175.1-66.8-84.3000113.8A294 S295 A296 G300 T301 D309 H312 E313 W316A294-F298 HydrophobicContact CB-CB 4.16Å; S295-F298 PolarHBondContact O-N 3.32Å; S295-F298 WeakPolarHBondContact OG-CD2 3.18Å; A296-F298 VanDerWaalsContact C-N 3.31Å; A296-F298 PolarHBondContact O-N 2.61Å; F298-G300 PolarHBondContact O-N 3.48Å; F298-T301 WeakPolarHBondContact O-CB 3.44Å; F298-T301 VanDerWaalsContact O-CG2 3.29Å; F298-T301 WeakPolarHBondContact O-CG2 3.46Å; F298-T301 PolarHBondContact O-N 3.04Å; F298-T301 VanDerWaalsContact O-N 3.11Å; F298-T301 PolarHBondContact O-OG1 2.88Å; F298-D309 VanDerWaalsContact O-CB 3.25Å; F298-D309 WeakPolarHBondContact O-CB 3.4Å; F298-H312 HydrophobicContact CD1-CB 3.81Å; F298-H312 HydrophobicContact CE1-CB 4.37Å; F298-E313 HydrophobicContact CB-CB 4.17Å; F298-E313 HydrophobicContact CD1-CB 4.15Å; F298-E313 HydrophobicContact CD2-CB 3.74Å; F298-E313 HydrophobicContact CD2-CG 3.64Å; F298-E313 WeakPolarHBondContact CD2-OE1 3.48Å; F298-E313 HydrophobicContact CE2-CB 4.19Å; F298-E313 HydrophobicContact CE2-CG 3.89Å; F298-E313 HydrophobicContact CG-CB 3.74Å; F298-E313 HydrophobicContact CG-CG 4.18Å; F298-W316 HydrophobicContact CE1-CB 3.81Å; F298-W316 HydrophobicContact CE1-CG 4.4Å; F298-W316 HydrophobicContact CE2-CB 4.28Å; F298-W316 HydrophobicContact CE2-CD2 4.2Å; F298-W316 HydrophobicContact CE2-CE3 4.36Å; F298-W316 HydrophobicContact CE2-CG 4.16Å; F298-W316 HydrophobicContact CZ-CB 3.34Å; F298-W316 HydrophobicContact CZ-CD2 4Å; F298-W316 HydrophobicContact CZ-CE3 4.49Å; F298-W316 AromaticContact CZ-CG 3.48Å; F298-W316 HydrophobicContact CZ-CG 3.48Å; F298-W316 VanDerWaalsContact CZ-CG 3.48Å
299K95.1Very high93.2Very high120 Ų12037.9 Ų37.952%0.52225%0.251SS..THydrogen-bonded Turntrans-56.6124.7176.1-76177.6-172.9174.10111.4A294 S295 T301 D309A294-K299 HydrophobicContact CB-CG 4.5Å; A294-K299 WeakPolarHBondContact O-CE 3.24Å; S295-K299 WeakPolarHBondContact O-CG 3.47Å; S295-K299 PolarHBondContact O-N 3.04Å; S295-K299 VanDerWaalsContact O-N 3.13Å; K299-T301 VanDerWaalsContact C-N 3.3Å; K299-D309 WeakPolarHBondContact CA-OD2 3.39Å
300G94.5Very high93.4Very high69 Ų6937.1 Ų37.171%0.71125%0.248SC*.THydrogen-bonded Turntrans7415.9178.900000114.5F298 D309F298-G300 PolarHBondContact O-N 3.48Å; G300-D309 VanDerWaalsContact N-CG 3.26Å; G300-D309 PolarHBondContact N-OD1 3.17Å; G300-D309 PolarHBondContact N-OD2 3.17Å
301T95.2Very high93.9Very high68 Ų6836.7 Ų36.742%0.41725%0.245SC..  trans-84.8-19.217762.10000112.6F298 K299 D309 H312F298-T301 WeakPolarHBondContact O-CB 3.44Å; F298-T301 VanDerWaalsContact O-CG2 3.29Å; F298-T301 WeakPolarHBondContact O-CG2 3.46Å; F298-T301 PolarHBondContact O-N 3.04Å; F298-T301 VanDerWaalsContact O-N 3.11Å; F298-T301 PolarHBondContact O-OG1 2.88Å; K299-T301 VanDerWaalsContact C-N 3.3Å; T301-D309 PolarHBondContact N-OD1 3.36Å; T301-D309 PolarHBondContact OG1-OD1 3.22Å; T301-H312 PolarHBondContact O-CE1 3.32Å; T301-H312 PolarHBondContact OG1-ND1 3.49Å
302S94Very high94.3Very high16 Ų1638 Ų3811%0.11225%0.251CS..SBendtrans-108.7146.9179.9-167.90000113.3L53 H304 G308 D309L53-S302 WeakPolarHBondContact CD1-OG 3.37Å; S302-H304 PolarHBondContact O-N 3.08Å; S302-H304 PolarHBondContact OG-N 2.53Å; S302-G308 WeakPolarHBondContact OG-CA 3.42Å; S302-D309 WeakPolarHBondContact CB-OD1 3.35Å; S302-D309 PolarHBondContact N-OD1 3.15Å
303S90.8Very high94.8Very high99 Ų9937.7 Ų37.769%0.69225%0.25SC*.THydrogen-bonded Turntrans-71.3-12.9167.756.70000113.1G305S303-G305 VanDerWaalsContact C-N 3.29Å; S303-G305 PolarHBondContact O-N 2.78Å
304H89.9Confident95Very high83 Ų8337.3 Ų37.338%0.38425%0.248SC..THydrogen-bonded Turntrans-94.923.5-179-63.2-79.2000112.8T52 S302 G308T52-H304 PolarHBondContact OG1-NE2 2.89Å; S302-H304 PolarHBondContact O-N 3.08Å; S302-H304 PolarHBondContact OG-N 2.53Å; H304-G308 PolarHBondContact O-N 3.13Å
305G90.9Very high95.2Very high36 Ų3637.3 Ų37.337%0.37125%0.247SC..Hα-helixtrans58.7-150.9-178.300000112.6S303 Y307 G308 D309S303-G305 VanDerWaalsContact C-N 3.29Å; S303-G305 PolarHBondContact O-N 2.78Å; G305-Y307 PolarHBondContact O-N 2.8Å; G305-G308 PolarHBondContact O-N 3.19Å; G305-G308 VanDerWaalsContact O-N 3.09Å; G305-D309 PolarHBondContact O-N 3.16Å
306V91.8Very high95.4Very high52 Ų5239.9 Ų39.932%0.31526%0.256SS..Hα-helixtrans-63.1-28-174.1-171.10000112.4L292 D309 A310L292-V306 HydrophobicContact CB-CB 4.28Å; L292-V306 HydrophobicContact CB-CG1 3.81Å; V306-D309 PolarHBondContact O-N 2.8Å; V306-A310 WeakPolarHBondContact O-CB 3.14Å; V306-A310 PolarHBondContact O-N 2.75Å
307Y93.9Very high95.5Very high12 Ų1236.3 Ų36.35%0.04723%0.227CC..Hα-helixtrans-59.5-53.1173.6-179.3-93.9000110.6D44 L53 V288 L292 G305 D309 A310 V311 H356 G358D44-Y307 VanDerWaalsContact CG-OH 3.32Å; D44-Y307 PolarHBondContact OD2-OH 3.43Å; L53-Y307 HydrophobicContact CD2-CE1 4.47Å; V288-Y307 HydrophobicContact CB-CD2 4.13Å; V288-Y307 HydrophobicContact CB-CE2 3.64Å; V288-Y307 HydrophobicContact CG1-CE2 4.48Å; V288-Y307 HydrophobicContact CG2-CD2 4.3Å; V288-Y307 HydrophobicContact CG2-CE2 3.34Å; V288-Y307 WeakPolarHBondContact CG2-OH 3.36Å; L292-Y307 HydrophobicContact CD1-CD2 4.29Å; L292-Y307 HydrophobicContact CD2-CD2 4.04Å; G305-Y307 PolarHBondContact O-N 2.8Å; Y307-D309 VanDerWaalsContact C-N 3.35Å; Y307-D309 PolarHBondContact O-N 3.17Å; Y307-A310 WeakPolarHBondContact O-CB 3.42Å; Y307-A310 PolarHBondContact O-N 3.36Å; Y307-V311 HydrophobicContact CD1-CG2 4.26Å; Y307-V311 HydrophobicContact CE1-CG2 3.84Å; Y307-V311 PolarHBondContact O-N 3.01Å; Y307-H356 VanDerWaalsContact CD2-O 3.29Å; Y307-H356 WeakPolarHBondContact CD2-O 3.22Å; Y307-G358 WeakPolarHBondContact OH-CA 3.3Å
308G95.4Very high95.6Very high0 Ų032.7 Ų32.70%020%0.197CC..Hα-helixtrans-68.5-33.6179.800000113.4L53 S302 H304 G305 A310 V311 H312L53-G308 VanDerWaalsContact CD1-CA 3.42Å; S302-G308 WeakPolarHBondContact OG-CA 3.42Å; H304-G308 PolarHBondContact O-N 3.13Å; G305-G308 PolarHBondContact O-N 3.19Å; G305-G308 VanDerWaalsContact O-N 3.09Å; G308-A310 VanDerWaalsContact C-N 3.28Å; G308-A310 PolarHBondContact O-N 2.7Å; G308-V311 PolarHBondContact O-N 3.02Å; G308-H312 VanDerWaalsContact O-CG 3.32Å; G308-H312 PolarHBondContact O-N 3.21Å
309D95.8Very high95.7Very high6 Ų631.1 Ų31.13%0.03219%0.19CC..Hα-helixtrans-60-41.6172.2-64.7-22.5000111A294 F298 K299 G300 T301 S302 G305 V306 Y307 H312 E313A294-D309 HydrophobicContact CB-CB 3.74Å; F298-D309 VanDerWaalsContact O-CB 3.25Å; F298-D309 WeakPolarHBondContact O-CB 3.4Å; K299-D309 WeakPolarHBondContact CA-OD2 3.39Å; G300-D309 VanDerWaalsContact N-CG 3.26Å; G300-D309 PolarHBondContact N-OD1 3.17Å; G300-D309 PolarHBondContact N-OD2 3.17Å; T301-D309 PolarHBondContact N-OD1 3.36Å; T301-D309 PolarHBondContact OG1-OD1 3.22Å; S302-D309 WeakPolarHBondContact CB-OD1 3.35Å; S302-D309 PolarHBondContact N-OD1 3.15Å; G305-D309 PolarHBondContact O-N 3.16Å; V306-D309 PolarHBondContact O-N 2.8Å; Y307-D309 VanDerWaalsContact C-N 3.35Å; Y307-D309 PolarHBondContact O-N 3.17Å; D309-H312 PolarHBondContact O-N 3.29Å; D309-E313 PolarHBondContact O-N 3.05Å
310A96.2Very high95.9Very high0 Ų027.8 Ų27.80%018%0.177CC..Hα-helixtrans-67.3-39.4176.600000112.1Q287 V288 F293 V306 Y307 G308 E313 V314Q287-A310 HydrophobicContact CG-CB 3.95Å; V288-A310 HydrophobicContact CG1-CB 3.85Å; F293-A310 WeakPolarHBondContact O-CB 3.44Å; V306-A310 WeakPolarHBondContact O-CB 3.14Å; V306-A310 PolarHBondContact O-N 2.75Å; Y307-A310 WeakPolarHBondContact O-CB 3.42Å; Y307-A310 PolarHBondContact O-N 3.36Å; G308-A310 VanDerWaalsContact C-N 3.28Å; G308-A310 PolarHBondContact O-N 2.7Å; A310-E313 PolarHBondContact O-N 3.15Å; A310-V314 WeakPolarHBondContact O-CG2 3.33Å; A310-V314 PolarHBondContact O-N 2.91Å
311V97.8Very high96.1Very high1 Ų124.5 Ų24.51%0.00614%0.143CC..Hα-helixtrans-63.5-43.6173.1175.90000111.4L40 L53 T55 V288 Y307 G308 E313 V314 D315L40-V311 HydrophobicContact CD1-CG2 4Å; L53-V311 HydrophobicContact CD1-CB 4.27Å; L53-V311 HydrophobicContact CD1-CG1 4.45Å; L53-V311 HydrophobicContact CD2-CB 3.84Å; L53-V311 HydrophobicContact CD2-CG1 3.66Å; L53-V311 HydrophobicContact CD2-CG2 3.88Å; L53-V311 HydrophobicContact CG-CB 4.3Å; L53-V311 HydrophobicContact CG-CG1 4Å; T55-V311 HydrophobicContact CG2-CG1 3.61Å; V288-V311 HydrophobicContact CG1-CG2 3.64Å; V288-V311 HydrophobicContact CG2-CG2 4.5Å; Y307-V311 HydrophobicContact CD1-CG2 4.26Å; Y307-V311 HydrophobicContact CE1-CG2 3.84Å; Y307-V311 PolarHBondContact O-N 3.01Å; G308-V311 PolarHBondContact O-N 3.02Å; V311-E313 VanDerWaalsContact C-N 3.26Å; V311-E313 PolarHBondContact O-N 3.38Å; V311-V314 PolarHBondContact O-N 3.06Å; V311-D315 PolarHBondContact O-N 3.43Å
312H98.2Very high96.3Very high26 Ų2621.6 Ų21.612%0.1212%0.124CC..Hα-helixtrans-59.9-37.8175.4-70.4174.5000112R54 F298 T301 G308 D309 D315 W316R54-H312 PolarHBondContact N-NE2 3.26Å; R54-H312 PolarHBondContact O-CD2 3.01Å; F298-H312 HydrophobicContact CD1-CB 3.81Å; F298-H312 HydrophobicContact CE1-CB 4.37Å; T301-H312 PolarHBondContact O-CE1 3.32Å; T301-H312 PolarHBondContact OG1-ND1 3.49Å; G308-H312 VanDerWaalsContact O-CG 3.32Å; G308-H312 PolarHBondContact O-N 3.21Å; D309-H312 PolarHBondContact O-N 3.29Å; H312-D315 PolarHBondContact O-N 3.18Å; H312-W316 PolarHBondContact O-N 3.24Å
313E98.5Very high96.5Very high0 Ų026 Ų260%014%0.143CC..Hα-helixtrans-69-39177-171.8171.8-111.300112.6T260 Q261 S295 F298 D309 A310 V311 W316 S317T260-E313 VanDerWaalsContact CB-OE2 3.28Å; T260-E313 WeakPolarHBondContact CB-OE2 2.98Å; T260-E313 HydrophobicContact CG2-CG 3.79Å; T260-E313 PolarHBondContact OG1-OE2 2.85Å; Q261-E313 VanDerWaalsContact NE2-CD 3.31Å; Q261-E313 PolarHBondContact NE2-OE1 3.45Å; Q261-E313 PolarHBondContact OE1-OE1 3.35Å; S295-E313 WeakPolarHBondContact CA-OE1 3.35Å; S295-E313 WeakPolarHBondContact CB-OE1 3.15Å; S295-E313 PolarHBondContact N-OE1 3.18Å; S295-E313 PolarHBondContact OG-OE1 3.04Å; F298-E313 HydrophobicContact CB-CB 4.17Å; F298-E313 HydrophobicContact CD1-CB 4.15Å; F298-E313 HydrophobicContact CD2-CB 3.74Å; F298-E313 HydrophobicContact CD2-CG 3.64Å; F298-E313 WeakPolarHBondContact CD2-OE1 3.48Å; F298-E313 HydrophobicContact CE2-CB 4.19Å; F298-E313 HydrophobicContact CE2-CG 3.89Å; F298-E313 HydrophobicContact CG-CB 3.74Å; F298-E313 HydrophobicContact CG-CG 4.18Å; D309-E313 PolarHBondContact O-N 3.05Å; A310-E313 PolarHBondContact O-N 3.15Å; V311-E313 VanDerWaalsContact C-N 3.26Å; V311-E313 PolarHBondContact O-N 3.38Å; E313-W316 HydrophobicContact CG-CE3 4.42Å; E313-W316 WeakPolarHBondContact O-CB 3.12Å; E313-W316 PolarHBondContact O-N 2.93Å; E313-S317 PolarHBondContact O-N 3.42Å
314V98.5Very high96.9Very high0 Ų021.6 Ų21.60%011%0.113CC..Hα-helixtrans-64.5-42.8172.6175.30000110.9L37 Y285 Q287 A310 V311 W316 S317 V318L37-V314 HydrophobicContact CD1-CG1 4.32Å; L37-V314 HydrophobicContact CD2-CB 4.16Å; L37-V314 HydrophobicContact CD2-CG1 3.6Å; L37-V314 HydrophobicContact CD2-CG2 4.26Å; L37-V314 HydrophobicContact CG-CG1 4Å; Y285-V314 HydrophobicContact CD1-CG1 4.41Å; Y285-V314 HydrophobicContact CD1-CG2 4.25Å; Y285-V314 HydrophobicContact CD2-CG1 4Å; Y285-V314 HydrophobicContact CE1-CG1 4.27Å; Y285-V314 HydrophobicContact CE2-CG1 3.83Å; Y285-V314 HydrophobicContact CG-CG1 4.27Å; Y285-V314 HydrophobicContact CG-CG2 4.34Å; Q287-V314 HydrophobicContact CB-CG2 3.34Å; Q287-V314 HydrophobicContact CG-CG2 3.92Å; A310-V314 WeakPolarHBondContact O-CG2 3.33Å; A310-V314 PolarHBondContact O-N 2.91Å; V311-V314 PolarHBondContact O-N 3.06Å; V314-W316 VanDerWaalsContact C-N 3.29Å; V314-W316 PolarHBondContact O-N 2.91Å; V314-S317 WeakPolarHBondContact O-CA 3.48Å; V314-S317 WeakPolarHBondContact O-CB 3.23Å; V314-S317 PolarHBondContact O-N 3.18Å; V314-V318 HydrophobicContact CG1-CG2 4.46Å; V314-V318 WeakPolarHBondContact O-CG2 3.28Å; V314-V318 PolarHBondContact O-N 3.44Å
315D98.8Very high97.3Very high6 Ų617.7 Ų17.73%0.0329%0.094CC..Hα-helixtrans-58.3-42.7175.5-17880.7000111.7T55 P56 N57 I58 V311 H312 S317 V318 G319T55-D315 VanDerWaalsContact C-CG 3.5Å; T55-D315 WeakPolarHBondContact CA-OD1 3.36Å; T55-D315 HydrophobicContact CG2-CB 4.4Å; T55-D315 VanDerWaalsContact O-OD1 3.12Å; P56-D315 WeakPolarHBondContact CD-OD2 3.37Å; P56-D315 WeakPolarHBondContact CG-OD2 3.48Å; N57-D315 WeakPolarHBondContact CB-O 3.41Å; N57-D315 PolarHBondContact N-OD1 3.44Å; N57-D315 PolarHBondContact N-OD2 3.04Å; N57-D315 PolarHBondContact ND2-O 2.55Å; N57-D315 PolarHBondContact ND2-OD2 3.02Å; I58-D315 HydrophobicContact CD1-CB 4.28Å; I58-D315 WeakPolarHBondContact CG1-OD1 3.5Å; I58-D315 PolarHBondContact N-OD1 2.85Å; V311-D315 PolarHBondContact O-N 3.43Å; H312-D315 PolarHBondContact O-N 3.18Å; D315-S317 PolarHBondContact O-N 3.05Å; D315-V318 WeakPolarHBondContact O-CB 3.13Å; D315-V318 PolarHBondContact O-N 2.79Å; D315-G319 PolarHBondContact O-N 3.46Å
316W98.8Very high97.7Very high57 Ų5720 Ų2022%0.21610%0.098CC..Hα-helixtrans-58.5-45.1171.5162.782.5000112.5Q261 T264 F298 H312 E313 V314 V318 G319 Q320Q261-W316 HydrophobicContact CB-CH2 4.29Å; Q261-W316 HydrophobicContact CB-CZ3 4.5Å; Q261-W316 HydrophobicContact CG-CH2 3.78Å; Q261-W316 HydrophobicContact CG-CZ3 3.92Å; T264-W316 HydrophobicContact CG2-CH2 4Å; T264-W316 HydrophobicContact CG2-CZ3 4.09Å; T264-W316 WeakPolarHBondContact OG1-CZ3 3.04Å; F298-W316 HydrophobicContact CE1-CB 3.81Å; F298-W316 HydrophobicContact CE1-CG 4.4Å; F298-W316 HydrophobicContact CE2-CB 4.28Å; F298-W316 HydrophobicContact CE2-CD2 4.2Å; F298-W316 HydrophobicContact CE2-CE3 4.36Å; F298-W316 HydrophobicContact CE2-CG 4.16Å; F298-W316 HydrophobicContact CZ-CB 3.34Å; F298-W316 HydrophobicContact CZ-CD2 4Å; F298-W316 HydrophobicContact CZ-CE3 4.49Å; F298-W316 AromaticContact CZ-CG 3.48Å; F298-W316 HydrophobicContact CZ-CG 3.48Å; F298-W316 VanDerWaalsContact CZ-CG 3.48Å; H312-W316 PolarHBondContact O-N 3.24Å; E313-W316 HydrophobicContact CG-CE3 4.42Å; E313-W316 WeakPolarHBondContact O-CB 3.12Å; E313-W316 PolarHBondContact O-N 2.93Å; V314-W316 VanDerWaalsContact C-N 3.29Å; V314-W316 PolarHBondContact O-N 2.91Å; W316-V318 VanDerWaalsContact C-N 3.33Å; W316-V318 PolarHBondContact O-N 3.47Å; W316-G319 WeakPolarHBondContact O-CA 3.41Å; W316-G319 PolarHBondContact O-N 3Å; W316-G319 VanDerWaalsContact O-N 3.09Å; W316-Q320 HydrophobicContact CD2-CG 4.19Å; W316-Q320 HydrophobicContact CH2-CG 4.25Å; W316-Q320 HydrophobicContact CZ2-CG 3.63Å; W316-Q320 PolarHBondContact O-N 3.2Å
317S98.9Very high98Very high0 Ų024 Ų240%011%0.107CC..Hα-helixtrans-59.1-44.7177.4176.80000111.1T264 Y285 E313 V314 D315 G319 Q320 I321T264-S317 WeakPolarHBondContact OG1-CB 3.25Å; T264-S317 PolarHBondContact OG1-OG 3.36Å; Y285-S317 WeakPolarHBondContact CE1-OG 3.03Å; Y285-S317 WeakPolarHBondContact OH-CB 3.36Å; Y285-S317 PolarHBondContact OH-OG 2.77Å; E313-S317 PolarHBondContact O-N 3.42Å; V314-S317 WeakPolarHBondContact O-CA 3.48Å; V314-S317 WeakPolarHBondContact O-CB 3.23Å; V314-S317 PolarHBondContact O-N 3.18Å; D315-S317 PolarHBondContact O-N 3.05Å; S317-G319 VanDerWaalsContact C-N 3.3Å; S317-G319 PolarHBondContact O-N 3.09Å; S317-Q320 WeakPolarHBondContact O-CB 3.36Å; S317-Q320 PolarHBondContact O-N 2.87Å; S317-Q320 VanDerWaalsContact O-N 3.11Å; S317-I321 WeakPolarHBondContact O-CG1 3.41Å; S317-I321 PolarHBondContact O-N 3.33Å; S317-I321 VanDerWaalsContact O-N 3.1Å
318V98.9Very high98.2Very high1 Ų125.5 Ų25.51%0.00612%0.116CC..Hα-helixtrans-55.8-47.3173.1174.30000110.2M35 N57 I58 V314 D315 W316 Q320 I321 L322 L338M35-V318 HydrophobicContact SD-CG1 4.34Å; M35-V318 HydrophobicContact SD-CG2 3.89Å; N57-V318 HydrophobicContact CB-CB 4.46Å; N57-V318 HydrophobicContact CB-CG1 4.33Å; I58-V318 HydrophobicContact CD1-CG2 4.4Å; I58-V318 HydrophobicContact CG1-CB 4.26Å; I58-V318 HydrophobicContact CG1-CG1 4.23Å; I58-V318 HydrophobicContact CG1-CG2 4.01Å; V314-V318 HydrophobicContact CG1-CG2 4.46Å; V314-V318 WeakPolarHBondContact O-CG2 3.28Å; V314-V318 PolarHBondContact O-N 3.44Å; D315-V318 WeakPolarHBondContact O-CB 3.13Å; D315-V318 PolarHBondContact O-N 2.79Å; W316-V318 VanDerWaalsContact C-N 3.33Å; W316-V318 PolarHBondContact O-N 3.47Å; V318-Q320 VanDerWaalsContact C-N 3.31Å; V318-Q320 PolarHBondContact O-N 3.25Å; V318-I321 WeakPolarHBondContact O-CB 3.38Å; V318-I321 PolarHBondContact O-N 3.21Å; V318-I321 VanDerWaalsContact O-N 3.1Å; V318-L322 HydrophobicContact CG1-CD1 4.22Å; V318-L322 HydrophobicContact CG1-CG 4.32Å; V318-L322 WeakPolarHBondContact O-CG 3.34Å; V318-L322 PolarHBondContact O-N 3.38Å; V318-L338 HydrophobicContact CG2-CD1 3.93Å
319G98.8Very high98.3Very high1 Ų136.3 Ų36.31%0.0116%0.157CC..Hα-helixtrans-56.2-40.2175.200000114N57 D315 W316 S317 L322 Q323N57-G319 VanDerWaalsContact CG-CA 3.49Å; N57-G319 VanDerWaalsContact OD1-CA 3.28Å; N57-G319 WeakPolarHBondContact OD1-CA 3.18Å; D315-G319 PolarHBondContact O-N 3.46Å; W316-G319 WeakPolarHBondContact O-CA 3.41Å; W316-G319 PolarHBondContact O-N 3Å; W316-G319 VanDerWaalsContact O-N 3.09Å; S317-G319 VanDerWaalsContact C-N 3.3Å; S317-G319 PolarHBondContact O-N 3.09Å; G319-L322 PolarHBondContact O-N 3.45Å; G319-Q323 WeakPolarHBondContact O-CB 3.33Å; G319-Q323 WeakPolarHBondContact O-CG 3.36Å; G319-Q323 PolarHBondContact O-N 3.18Å
320Q98.9Very high98.4Very high51 Ų5136.8 Ų36.824%0.23816%0.16CC..Hα-helixtrans-64.4-38.7175.8-65.9-56.6-79.900112.6T264 W316 S317 V318 T324T264-Q320 HydrophobicContact CG2-CB 3.61Å; T264-Q320 HydrophobicContact CG2-CG 3.94Å; W316-Q320 HydrophobicContact CD2-CG 4.19Å; W316-Q320 HydrophobicContact CH2-CG 4.25Å; W316-Q320 HydrophobicContact CZ2-CG 3.63Å; W316-Q320 PolarHBondContact O-N 3.2Å; S317-Q320 WeakPolarHBondContact O-CB 3.36Å; S317-Q320 PolarHBondContact O-N 2.87Å; S317-Q320 VanDerWaalsContact O-N 3.11Å; V318-Q320 VanDerWaalsContact C-N 3.31Å; V318-Q320 PolarHBondContact O-N 3.25Å; Q320-T324 WeakPolarHBondContact O-CB 3.26Å; Q320-T324 PolarHBondContact O-N 2.9Å; Q320-T324 PolarHBondContact O-OG1 3.39Å
321I98.9Very high98.4Very high0 Ų037.6 Ų37.60%016%0.163CC..Hα-helixtrans-64.7-48.3174.6-59.1-53.6000110.4I33 A267 V268 I271 L283 S317 V318 Q323 T324 L325I33-I321 HydrophobicContact CD1-CG2 3.85Å; I33-I321 HydrophobicContact CG2-CG2 4.29Å; A267-I321 HydrophobicContact CB-CD1 3.68Å; V268-I321 HydrophobicContact CG2-CD1 4.18Å; I271-I321 HydrophobicContact CD1-CD1 3.99Å; I271-I321 HydrophobicContact CD1-CG2 3.98Å; L283-I321 HydrophobicContact CD2-CD1 4.4Å; L283-I321 HydrophobicContact CD2-CG1 4.23Å; S317-I321 WeakPolarHBondContact O-CG1 3.41Å; S317-I321 PolarHBondContact O-N 3.33Å; S317-I321 VanDerWaalsContact O-N 3.1Å; V318-I321 WeakPolarHBondContact O-CB 3.38Å; V318-I321 PolarHBondContact O-N 3.21Å; V318-I321 VanDerWaalsContact O-N 3.1Å; I321-Q323 PolarHBondContact O-N 2.93Å; I321-T324 WeakPolarHBondContact O-CB 3.49Å; I321-T324 PolarHBondContact O-N 3.49Å; I321-L325 HydrophobicContact CG2-CD1 4.25Å; I321-L325 WeakPolarHBondContact O-CG 3.23Å; I321-L325 PolarHBondContact O-N 2.97Å
322L98.8Very high98.3Very high6 Ų644.9 Ų44.93%0.03120%0.197CC..Hα-helixtrans-57.6-51.5178.6-62.7-178000111.7L61 V318 G319 T324 L325 D326 L336L61-L322 HydrophobicContact CD1-CD2 4.33Å; V318-L322 HydrophobicContact CG1-CD1 4.22Å; V318-L322 HydrophobicContact CG1-CG 4.32Å; V318-L322 WeakPolarHBondContact O-CG 3.34Å; V318-L322 PolarHBondContact O-N 3.38Å; G319-L322 PolarHBondContact O-N 3.45Å; L322-T324 PolarHBondContact O-N 2.94Å; L322-L325 PolarHBondContact O-N 3.12Å; L322-L325 VanDerWaalsContact O-N 3.12Å; L322-D326 PolarHBondContact O-N 3.31Å; L322-L336 HydrophobicContact CD2-CD1 3.39Å
323Q98.8Very high98.3Very high108 Ų10845.8 Ų45.851%0.50520%0.203SC..Hα-helixtrans-58.8-35.8178.2-71.2169.323.500112.6G319 I321 R327G319-Q323 WeakPolarHBondContact O-CB 3.33Å; G319-Q323 WeakPolarHBondContact O-CG 3.36Å; G319-Q323 PolarHBondContact O-N 3.18Å; I321-Q323 PolarHBondContact O-N 2.93Å; Q323-R327 VanDerWaalsContact O-CB 3.28Å; Q323-R327 WeakPolarHBondContact O-CB 3.35Å; Q323-R327 PolarHBondContact O-N 2.77Å
324T98.9Very high98.3Very high8 Ų845.8 Ų45.85%0.04920%0.203CC..Hα-helixtrans-67.5-44.4176.9-66.10000111.6V268 I271 E272 Q320 I321 L322 D326 R327 L328V268-T324 HydrophobicContact CG1-CG2 4.14Å; I271-T324 HydrophobicContact CB-CG2 4.25Å; I271-T324 HydrophobicContact CG2-CG2 3.93Å; E272-T324 HydrophobicContact CG-CG2 4.44Å; Q320-T324 WeakPolarHBondContact O-CB 3.26Å; Q320-T324 PolarHBondContact O-N 2.9Å; Q320-T324 PolarHBondContact O-OG1 3.39Å; I321-T324 WeakPolarHBondContact O-CB 3.49Å; I321-T324 PolarHBondContact O-N 3.49Å; L322-T324 PolarHBondContact O-N 2.94Å; T324-D326 VanDerWaalsContact C-N 3.32Å; T324-D326 PolarHBondContact O-N 2.94Å; T324-R327 PolarHBondContact O-N 3.43Å; T324-L328 HydrophobicContact CG2-CD1 3.7Å; T324-L328 HydrophobicContact CG2-CG 4.44Å; T324-L328 WeakPolarHBondContact O-CB 3.35Å; T324-L328 VanDerWaalsContact O-CG 3.27Å; T324-L328 WeakPolarHBondContact O-CG 3.23Å; T324-L328 PolarHBondContact O-N 3.21Å
325L98.6Very high98.3Very high0 Ų045.8 Ų45.80%020%0.203CC..Hα-helixtrans-62-40.4176.8-64.7169.3000112.3I33 I271 F279 I321 L322 R329 V330 R331 T334 L336I33-L325 HydrophobicContact CD1-CD1 3.97Å; I33-L325 HydrophobicContact CD1-CD2 3.78Å; I33-L325 HydrophobicContact CD1-CG 4.26Å; I271-L325 HydrophobicContact CG2-CD2 4.11Å; F279-L325 HydrophobicContact CZ-CD2 4.43Å; I321-L325 HydrophobicContact CG2-CD1 4.25Å; I321-L325 WeakPolarHBondContact O-CG 3.23Å; I321-L325 PolarHBondContact O-N 2.97Å; L322-L325 PolarHBondContact O-N 3.12Å; L322-L325 VanDerWaalsContact O-N 3.12Å; L325-R329 PolarHBondContact O-N 3.39Å; L325-V330 HydrophobicContact CB-CG2 4.44Å; L325-V330 HydrophobicContact CD2-CG2 3.65Å; L325-V330 PolarHBondContact O-N 3.47Å; L325-R331 HydrophobicContact CB-CB 4.24Å; L325-T334 HydrophobicContact CD1-CG2 4.34Å; L325-T334 HydrophobicContact CD2-CG2 4.21Å; L325-L336 HydrophobicContact CD1-CD1 4.38Å; L325-L336 HydrophobicContact CD1-CD2 3.86Å
326D98.3Very high98.3Very high84 Ų8445.5 Ų45.545%0.44920%0.201SC..Hα-helixtrans-67.4-46.3178.5-67.1-22.7000111.3L322 T324 L328 R329 R331L322-D326 PolarHBondContact O-N 3.31Å; T324-D326 VanDerWaalsContact C-N 3.32Å; T324-D326 PolarHBondContact O-N 2.94Å; D326-L328 VanDerWaalsContact C-N 3.3Å; D326-L328 PolarHBondContact O-N 3.11Å; D326-R329 PolarHBondContact O-N 3.17Å; D326-R329 VanDerWaalsContact O-N 3.07Å; D326-R331 WeakPolarHBondContact OD1-CB 3.48Å; D326-R331 WeakPolarHBondContact OD1-CG 3.2Å
327R98.5Very high98.3Very high136 Ų13642.8 Ų42.851%0.51319%0.191SC..Hα-helixtrans-59.2-41.1176.4177.3176.454.590.70.2112.1E272 Q323 T324 R329E272-R327 IonicContact OE1-CZ 3.13Å; E272-R327 IonicContact OE1-NH1 2.77Å; E272-R327 PolarHBondContact OE1-NH1 2.75Å; E272-R327 IonicContact OE1-NH2 2.65Å; E272-R327 PolarHBondContact OE1-NH2 3.4Å; Q323-R327 VanDerWaalsContact O-CB 3.28Å; Q323-R327 WeakPolarHBondContact O-CB 3.35Å; Q323-R327 PolarHBondContact O-N 2.77Å; T324-R327 PolarHBondContact O-N 3.43Å; R327-R329 VanDerWaalsContact C-N 3.29Å
328L98.3Very high98.3Very high44 Ų4442.8 Ų42.823%0.2319%0.191CC..THydrogen-bonded Turntrans-82.5-6.4178.8-64.4172000113.2I271 E272 T324 D326 V330I271-L328 HydrophobicContact CG2-CD1 3.73Å; E272-L328 HydrophobicContact CG-CD1 4.04Å; T324-L328 HydrophobicContact CG2-CD1 3.7Å; T324-L328 HydrophobicContact CG2-CG 4.44Å; T324-L328 WeakPolarHBondContact O-CB 3.35Å; T324-L328 VanDerWaalsContact O-CG 3.27Å; T324-L328 WeakPolarHBondContact O-CG 3.23Å; T324-L328 PolarHBondContact O-N 3.21Å; D326-L328 VanDerWaalsContact C-N 3.3Å; D326-L328 PolarHBondContact O-N 3.11Å; L328-V330 VanDerWaalsContact C-N 3.26Å; L328-V330 HydrophobicContact CB-CG2 4.07Å; L328-V330 PolarHBondContact O-N 3.08Å
329R97.4Very high98.3Very high227 Ų22742.7 Ų42.786%0.85719%0.191SC*.THydrogen-bonded Turntrans56.536.5-178.8-55-178.9179.3178.9-1.3113.8L325 D326 R327L325-R329 PolarHBondContact O-N 3.39Å; D326-R329 PolarHBondContact O-N 3.17Å; D326-R329 VanDerWaalsContact O-N 3.07Å; R327-R329 VanDerWaalsContact C-N 3.29Å
330V97.3Very high98.3Very high17 Ų1742.7 Ų42.710%0.10319%0.19CC..  trans-108.61.5176.1-64.50000112.6L325 L328 E332 N333 T334L325-V330 HydrophobicContact CB-CG2 4.44Å; L325-V330 HydrophobicContact CD2-CG2 3.65Å; L325-V330 PolarHBondContact O-N 3.47Å; L328-V330 VanDerWaalsContact C-N 3.26Å; L328-V330 HydrophobicContact CB-CG2 4.07Å; L328-V330 PolarHBondContact O-N 3.08Å; V330-E332 PolarHBondContact O-N 2.82Å; V330-N333 CarbonylContact O-C 3.55Å; V330-N333 PolarHBondContact O-N 2.81Å; V330-N333 VanDerWaalsContact O-N 3.1Å; V330-T334 PolarHBondContact O-N 3.1Å; V330-T334 PolarHBondContact O-OG1 3.04Å
331R96.6Very high98.3Very high16 Ų1640.2 Ų40.26%0.0618%0.179CC..G310 helixtrans-52.5-47.2-179.3-179.463.9178167.5-2.4113.6E64 L325 D326 N333 T334 L336 P384E64-R331 IonicContact OE2-CZ 3.95Å; E64-R331 IonicContact OE2-NE 2.82Å; E64-R331 IonicContact OE2-NH2 3.75Å; E64-R331 PolarHBondContact OE2-NH2 3.15Å; L325-R331 HydrophobicContact CB-CB 4.24Å; D326-R331 WeakPolarHBondContact OD1-CB 3.48Å; D326-R331 WeakPolarHBondContact OD1-CG 3.2Å; R331-N333 PolarHBondContact O-N 2.98Å; R331-T334 PolarHBondContact O-N 3.12Å; R331-L336 VanDerWaalsContact NH1-CG 3.31Å; R331-P384 HydrophobicContact CG-CG 4.11Å
332E96Very high98.2Very high154 Ų15440.2 Ų40.272%0.7218%0.179SC*.G310 helixtrans-70.4-18.1-178.6-62.9179.9176.200113.6V330 W383 P384V330-E332 PolarHBondContact O-N 2.82Å; E332-W383 VanDerWaalsContact O-CD1 3.3Å; E332-W383 PolarHBondContact O-NE1 3.23Å; E332-P384 HydrophobicContact CG-CB 4.46Å
333N97.3Very high98.2Very high45 Ų4540 Ų4024%0.24118%0.177CC..G310 helixtrans-105.720.1176.3-168.454.4000112.3I28 K29 P30 N31 V330 R331I28-N333 WeakPolarHBondContact CG2-ND2 3.38Å; I28-N333 WeakPolarHBondContact CG2-OD1 3.42Å; K29-N333 PolarHBondContact O-ND2 3.18Å; K29-N333 VanDerWaalsContact O-ND2 3.11Å; P30-N333 CarbonylContact C-O 3.59Å; P30-N333 WeakPolarHBondContact CA-O 3.47Å; N31-N333 PolarHBondContact N-O 2.69Å; V330-N333 CarbonylContact O-C 3.55Å; V330-N333 PolarHBondContact O-N 2.81Å; V330-N333 VanDerWaalsContact O-N 3.1Å; R331-N333 PolarHBondContact O-N 2.98Å
334T98.5Very high98.1Very high0 Ų034.8 Ų34.80%015%0.153CC..EExtended strand (participates in β ladder)trans-127.2119.7-176.4-55.50000110.6N31 I33 L325 V330 R331 L336N31-T334 HydrophobicContact CB-CG2 3.89Å; N31-T334 PolarHBondContact ND2-OG1 2.77Å; N31-T334 WeakPolarHBondContact O-CA 3.36Å; I33-T334 HydrophobicContact CD1-CG2 4.04Å; I33-T334 HydrophobicContact CG1-CG2 3.98Å; L325-T334 HydrophobicContact CD1-CG2 4.34Å; L325-T334 HydrophobicContact CD2-CG2 4.21Å; V330-T334 PolarHBondContact O-N 3.1Å; V330-T334 PolarHBondContact O-OG1 3.04Å; R331-T334 PolarHBondContact O-N 3.12Å; T334-L336 HydrophobicContact CG2-CD2 3.8Å
335L98.8Very high97.9Very high0 Ų034.9 Ų34.90%015%0.153CC..EExtended strand (participates in β ladder)trans-78.8120.1166.417563.2000109.1N31 F32 I33 L381 W383 I387 T405 L409N31-L335 PolarHBondContact O-N 3.3Å; F32-L335 HydrophobicContact CD1-CB 4.1Å; F32-L335 HydrophobicContact CD1-CD2 4.1Å; F32-L335 HydrophobicContact CE1-CD2 4.25Å; I33-L335 PolarHBondContact N-O 3.27Å; L335-L381 HydrophobicContact CD1-CD2 4.47Å; L335-W383 HydrophobicContact CB-CD2 4.15Å; L335-W383 HydrophobicContact CB-CE3 3.9Å; L335-W383 HydrophobicContact CB-CG 4.5Å; L335-W383 HydrophobicContact CB-CZ3 4.47Å; L335-W383 HydrophobicContact CD1-CB 4.03Å; L335-W383 HydrophobicContact CD1-CE3 4.11Å; L335-W383 HydrophobicContact CG-CE3 4.43Å; L335-I387 HydrophobicContact CD1-CD1 3.89Å; L335-T405 HydrophobicContact CD2-CG2 4.44Å; L335-L409 HydrophobicContact CD2-CD1 3.64Å
336L98.9Very high97.7Very high0 Ų036.5 Ų36.50%016%0.162CC..EExtended strand (participates in β ladder)trans-98.8138.9168.4-64.8-155.8000111.3I33 M35 L61 L322 L325 R331 T334 L381 S382I33-L336 HydrophobicContact CB-CD2 3.52Å; I33-L336 HydrophobicContact CD1-CD2 4.03Å; I33-L336 HydrophobicContact CG1-CD2 4.12Å; I33-L336 HydrophobicContact CG2-CD2 4.07Å; I33-L336 WeakPolarHBondContact O-CA 3.36Å; M35-L336 HydrophobicContact CE-CD1 4.14Å; L61-L336 HydrophobicContact CD1-CB 4.05Å; L61-L336 HydrophobicContact CD1-CD1 3.48Å; L61-L336 VanDerWaalsContact CD1-CD1 3.48Å; L61-L336 HydrophobicContact CD1-CG 4.32Å; L61-L336 HydrophobicContact CD2-CD1 4.46Å; L322-L336 HydrophobicContact CD2-CD1 3.39Å; L325-L336 HydrophobicContact CD1-CD1 4.38Å; L325-L336 HydrophobicContact CD1-CD2 3.86Å; R331-L336 VanDerWaalsContact NH1-CG 3.31Å; T334-L336 HydrophobicContact CG2-CD2 3.8Å; L336-L381 CarbonylContact O-C 3.52Å; L336-L381 VanDerWaalsContact O-CA 3.27Å; L336-L381 WeakPolarHBondContact O-CA 3.43Å; L336-S382 PolarHBondContact N-O 2.87Å; L336-S382 PolarHBondContact O-N 3.2Å
337Y98.9Very high97.3Very high0 Ų032.6 Ų32.60%014%0.141CC..EExtended strand (participates in β ladder)trans-131.9133.6168.4170.6-118.2000110I33 L34 M35 H71 F85 T339 I380 L381 N399 L402I33-Y337 PolarHBondContact O-N 3.38Å; L34-Y337 HydrophobicContact CD2-CD1 4.31Å; M35-Y337 PolarHBondContact N-O 2.96Å; H71-Y337 AromaticContact NE2-CE2 3.67Å; H71-Y337 AromaticContact NE2-CZ 3.63Å; H71-Y337 PolarHBondContact NE2-OH 3.27Å; F85-Y337 HydrophobicContact CD2-CE1 4.45Å; F85-Y337 HydrophobicContact CE2-CD1 4.14Å; F85-Y337 AromaticContact CE2-CE1 3.56Å; F85-Y337 HydrophobicContact CE2-CE1 3.56Å; F85-Y337 HydrophobicContact CZ-CD1 4.37Å; F85-Y337 HydrophobicContact CZ-CE1 4.15Å; Y337-T339 HydrophobicContact CD1-CG2 4.3Å; Y337-T339 HydrophobicContact CE1-CG2 3.33Å; Y337-T339 HydrophobicContact CE2-CG2 4.45Å; Y337-T339 VanDerWaalsContact CZ-CB 3.41Å; Y337-T339 VanDerWaalsContact CZ-CG2 3.47Å; Y337-T339 VanDerWaalsContact OH-CB 3.28Å; Y337-T339 WeakPolarHBondContact OH-CB 3.32Å; Y337-T339 VanDerWaalsContact OH-CG2 3.31Å; Y337-T339 WeakPolarHBondContact OH-CG2 3.37Å; Y337-T339 PolarHBondContact OH-OG1 3.01Å; Y337-I380 CarbonylContact C-O 3.57Å; Y337-I380 VanDerWaalsContact CA-O 3.3Å; Y337-I380 WeakPolarHBondContact CA-O 3.48Å; Y337-L381 HydrophobicContact CD2-CD1 3.7Å; Y337-L381 HydrophobicContact CD2-CD2 4.37Å; Y337-L381 HydrophobicContact CD2-CG 3.77Å; Y337-L381 HydrophobicContact CE2-CD1 4.04Å; Y337-N399 PolarHBondContact OH-OD1 2.99Å; Y337-N399 VanDerWaalsContact OH-OD1 3.04Å; Y337-L402 HydrophobicContact CD1-CD2 3.64Å; Y337-L402 HydrophobicContact CD1-CG 3.76Å; Y337-L402 HydrophobicContact CD2-CD2 3.56Å; Y337-L402 HydrophobicContact CD2-CG 4.5Å; Y337-L402 HydrophobicContact CE1-CD2 3.6Å; Y337-L402 HydrophobicContact CE1-CG 3.9Å; Y337-L402 HydrophobicContact CE2-CD2 3.49Å; Y337-L402 VanDerWaalsContact CE2-CD2 3.49Å; Y337-L402 HydrophobicContact CG-CD2 3.58Å; Y337-L402 HydrophobicContact CG-CG 4.04Å; Y337-L402 VanDerWaalsContact CZ-CD2 3.48Å
338L98.9Very high96.7Very high0 Ų026.5 Ų26.50%012%0.118CC..EExtended strand (participates in β ladder)trans-125.1130.5172-172148.8000110.6M35 L37 L45 I58 L61 V318 I380M35-L338 HydrophobicContact CB-CB 4.39Å; M35-L338 HydrophobicContact CB-CD1 4.43Å; M35-L338 HydrophobicContact CB-CG 4.31Å; M35-L338 HydrophobicContact CE-CB 4.35Å; M35-L338 HydrophobicContact CE-CD1 4.4Å; M35-L338 CarbonylContact O-C 3.51Å; M35-L338 VanDerWaalsContact O-CA 3.3Å; M35-L338 WeakPolarHBondContact O-CA 3.47Å; L37-L338 HydrophobicContact CD1-CD1 4.32Å; L37-L338 HydrophobicContact CD1-CD2 3.97Å; L37-L338 HydrophobicContact CD1-CG 4.06Å; L45-L338 HydrophobicContact CD1-CD2 4.35Å; I58-L338 HydrophobicContact CD1-CD1 4.08Å; I58-L338 HydrophobicContact CG1-CD1 3.85Å; I58-L338 HydrophobicContact CG2-CD1 4.12Å; I58-L338 HydrophobicContact CG2-CD2 4.23Å; L61-L338 HydrophobicContact CD2-CB 3.98Å; L61-L338 HydrophobicContact CD2-CD1 4.36Å; V318-L338 HydrophobicContact CG2-CD1 3.93Å; L338-I380 HydrophobicContact CB-CB 4.34Å; L338-I380 HydrophobicContact CD2-CD1 4.27Å; L338-I380 PolarHBondContact N-O 3.19Å; L338-I380 PolarHBondContact O-N 2.99Å
339T98.9Very high96Very high0 Ų027 Ų270%012%0.121CC..EExtended strand (participates in β ladder)trans-151.1-176.7177-163.70000112.9M35 M36 L37 Y337 P378 N399M35-T339 PolarHBondContact O-N 3.07Å; M36-T339 WeakPolarHBondContact CA-O 3.38Å; M36-T339 HydrophobicContact CB-CG2 4.37Å; M36-T339 HydrophobicContact CE-CG2 3.82Å; M36-T339 HydrophobicContact CG-CG2 4.26Å; L37-T339 WeakPolarHBondContact CD1-O 3.38Å; L37-T339 PolarHBondContact N-O 2.62Å; Y337-T339 HydrophobicContact CD1-CG2 4.3Å; Y337-T339 HydrophobicContact CE1-CG2 3.33Å; Y337-T339 HydrophobicContact CE2-CG2 4.45Å; Y337-T339 VanDerWaalsContact CZ-CB 3.41Å; Y337-T339 VanDerWaalsContact CZ-CG2 3.47Å; Y337-T339 VanDerWaalsContact OH-CB 3.28Å; Y337-T339 WeakPolarHBondContact OH-CB 3.32Å; Y337-T339 VanDerWaalsContact OH-CG2 3.31Å; Y337-T339 WeakPolarHBondContact OH-CG2 3.37Å; Y337-T339 PolarHBondContact OH-OG1 3.01Å; T339-P378 VanDerWaalsContact CA-O 3.25Å; T339-P378 WeakPolarHBondContact CA-O 3.43Å; T339-P378 VanDerWaalsContact CB-O 3.31Å; T339-P378 WeakPolarHBondContact CB-O 3.09Å; T339-P378 PolarHBondContact OG1-O 3.5Å; T339-N399 PolarHBondContact OG1-OD1 3.22Å
340S98.8Very high94.8Very high0 Ų017.7 Ų17.70%09%0.089CC..EExtended strand (participates in β ladder)trans-116150.8163.8-168.20000109.8L37 L40 Q342 N399L37-S340 WeakPolarHBondContact O-CA 3.37Å; L40-S340 PolarHBondContact N-OG 2.75Å; L40-S340 VanDerWaalsContact O-CB 3.3Å; L40-S340 WeakPolarHBondContact O-CB 3.41Å; L40-S340 PolarHBondContact O-OG 2.97Å; S340-Q342 VanDerWaalsContact C-N 3.3Å; S340-Q342 WeakPolarHBondContact CB-O 3.26Å; S340-Q342 PolarHBondContact OG-O 2.99Å; S340-N399 PolarHBondContact O-ND2 3.37Å; S340-N399 VanDerWaalsContact O-ND2 3.08Å
341D98.3Very high93.3Very high0 Ų021.9 Ų21.90%013%0.126CC..SBendtrans-66.1-33.6173.259.9-8.9000112.1M36 L37 D38 D39 A73 C78 S81 R82M36-D341 HydrophobicContact CG-CB 4.14Å; M36-D341 HydrophobicContact SD-CB 3.72Å; L37-D341 PolarHBondContact O-N 2.77Å; D38-D341 WeakPolarHBondContact CA-OD1 3.4Å; D38-D341 VanDerWaalsContact OD1-OD2 3.06Å; D39-D341 PolarHBondContact N-OD1 3.42Å; A73-D341 WeakPolarHBondContact CB-O 3.41Å; C78-D341 WeakPolarHBondContact CB-OD2 3.37Å; S81-D341 WeakPolarHBondContact CB-O 3.43Å; S81-D341 PolarHBondContact OG-O 2.86Å; R82-D341 HydrophobicContact CG-CB 4.23Å; R82-D341 IonicContact CZ-OD2 3.89Å; R82-D341 IonicContact NE-OD2 2.75Å; R82-D341 PolarHBondContact NE-OD2 3.46Å; R82-D341 IonicContact NH2-OD2 3.44Å; R82-D341 PolarHBondContact NH2-OD2 2.83Å
342Q98.5Very high92Very high0 Ų025.1 Ų25.10%016%0.155CC..SBendtrans-157.8-180170.458.9-82.1-21.700110.7D39 L77 C78 S340 K367 V377D39-Q342 PolarHBondContact OD1-NE2 3.26Å; L77-Q342 PolarHBondContact O-OE1 3.15Å; C78-Q342 VanDerWaalsContact CA-OE1 3.24Å; C78-Q342 VanDerWaalsContact N-OE1 3.14Å; C78-Q342 PolarHBondContact SG-NE2 2.9Å; S340-Q342 VanDerWaalsContact C-N 3.3Å; S340-Q342 WeakPolarHBondContact CB-O 3.26Å; S340-Q342 PolarHBondContact OG-O 2.99Å; Q342-K367 HydrophobicContact CG-CG 4.21Å; Q342-V377 VanDerWaalsContact C-CG1 3.47Å
343G97.9Very high90.8Very high0 Ų020.2 Ų20.20%015%0.146CC..  trans-71.1173.617600000114.4G373 G374G343-G373 WeakPolarHBondContact CA-O 3.14Å; G343-G374 PolarHBondContact N-O 3.11Å; G343-G374 VanDerWaalsContact N-O 3.11Å
344A96.9Very high89.8Confident0 Ų024.3 Ų24.30%016%0.164CC..  trans-67.4148.9-171.500000114.6D39 L346 G358 N360 G366 K367D39-A344 VanDerWaalsContact O-CA 3.3Å; D39-A344 WeakPolarHBondContact O-CA 3.19Å; A344-L346 PolarHBondContact O-N 3.42Å; A344-G358 VanDerWaalsContact CB-CA 3.48Å; A344-N360 WeakPolarHBondContact CB-OD1 3.46Å; A344-N360 PolarHBondContact N-OD1 3.11Å; A344-G366 CarbonylContact O-C 3.54Å; A344-G366 VanDerWaalsContact O-CA 3.29Å; A344-G366 WeakPolarHBondContact O-CA 3.5Å; A344-K367 PolarHBondContact O-N 3.11Å
345H94.6Very high88.7Confident10 Ų1028.7 Ų28.75%0.04619%0.191CC..  trans-83.796.3176.3-165.8173.7000111.7E347 E348 G357 K367 H484H345-E347 IonicContact CD2-OE2 3.82Å; H345-E347 PolarHBondContact CD2-OE2 3.49Å; H345-E347 VanDerWaalsContact CD2-OE2 3.28Å; H345-E347 IonicContact NE2-OE2 3.27Å; H345-E348 HydrophobicContact CB-CB 4.34Å; H345-E348 IonicContact CE1-OE2 2.79Å; H345-E348 IonicContact ND1-OE2 3.77Å; H345-E348 WeakPolarHBondContact O-CB 3Å; H345-G357 WeakPolarHBondContact O-CA 3.33Å; H345-K367 HydrophobicContact CB-CB 4.19Å; H345-K367 HydrophobicContact CB-CD 3.76Å; H345-H484 AromaticContact CE1-CE1 3.46Å; H345-H484 PolarHBondContact CE1-CE1 2.73Å; H345-H484 VanDerWaalsContact CE1-CE1 3.46Å; H345-H484 AromaticContact CE1-NE2 3.61Å; H345-H484 AromaticContact NE2-NE2 3.97Å; H345-H484 PolarHBondContact NE2-O 3.08Å
346L93.6Very high87.7Confident34 Ų3430.7 Ų30.718%0.17820%0.2CC..THydrogen-bonded Turntrans-74.3-28.2-174.6-58.6-173.5000113.9A344 E348 G358 A365 T479A344-L346 PolarHBondContact O-N 3.42Å; L346-E348 PolarHBondContact O-N 3.26Å; L346-G358 WeakPolarHBondContact CD2-O 3.47Å; L346-A365 VanDerWaalsContact CD1-C 3.4Å; L346-A365 WeakPolarHBondContact CD1-O 3.34Å; L346-T479 HydrophobicContact CB-CG2 3.69Å; L346-T479 HydrophobicContact CD1-CG2 4.09Å
347E90.6Very high86.7Confident1 Ų131.6 Ų31.61%0.00521%0.21CC..THydrogen-bonded Turntrans-78.70.6-178.8-62.780.2179.300113.5H345 L349 T479 C480 F481 H484H345-E347 IonicContact CD2-OE2 3.82Å; H345-E347 PolarHBondContact CD2-OE2 3.49Å; H345-E347 VanDerWaalsContact CD2-OE2 3.28Å; H345-E347 IonicContact NE2-OE2 3.27Å; E347-L349 PolarHBondContact O-N 3.29Å; E347-T479 WeakPolarHBondContact OE1-CA 3.34Å; E347-C480 PolarHBondContact OE1-N 3.01Å; E347-F481 VanDerWaalsContact CA-CE1 3.48Å; E347-F481 HydrophobicContact CB-CD1 4.16Å; E347-F481 HydrophobicContact CB-CE1 4.29Å; E347-F481 HydrophobicContact CG-CD1 4.47Å; E347-H484 WeakPolarHBondContact CB-O 3.37Å
348E86.9Confident86.3Confident9 Ų932 Ų324%0.04221%0.214CC..  trans-76.7114.2-174.9-173.861.1-165.400111.2R171 T290 H345 L346 V355 H356 H484R171-E348 IonicContact CZ-OE1 3.28Å; R171-E348 IonicContact CZ-OE2 3.89Å; R171-E348 IonicContact NE-OE1 2.72Å; R171-E348 PolarHBondContact NE-OE1 2.94Å; R171-E348 IonicContact NE-OE2 3.14Å; R171-E348 PolarHBondContact NE-OE2 3.22Å; R171-E348 IonicContact NH2-OE1 2.75Å; R171-E348 PolarHBondContact NH2-OE1 2.94Å; R171-E348 IonicContact NH2-OE2 3.98Å; R171-E348 PolarHBondContact NH2-OE2 3.35Å; T290-E348 WeakPolarHBondContact CB-OE1 3.41Å; T290-E348 WeakPolarHBondContact CG2-OE1 3.19Å; T290-E348 PolarHBondContact OG1-OE1 2.95Å; H345-E348 HydrophobicContact CB-CB 4.34Å; H345-E348 IonicContact CE1-OE2 2.79Å; H345-E348 IonicContact ND1-OE2 3.77Å; H345-E348 WeakPolarHBondContact O-CB 3Å; L346-E348 PolarHBondContact O-N 3.26Å; E348-V355 CarbonylContact O-C 3.58Å; E348-V355 WeakPolarHBondContact O-CA 3.36Å; E348-H356 HydrophobicContact CG-CB 4.08Å; E348-H356 PolarHBondContact O-N 2.87Å; E348-H484 IonicContact OE2-CE1 3.45Å; E348-H484 PolarHBondContact OE2-CE1 2.84Å; E348-H484 IonicContact OE2-NE2 2.79Å; E348-H484 PolarHBondContact OE2-NE2 3.48Å
349L81.8Confident86.1Confident55 Ų5538 Ų3829%0.28824%0.237SC..BIsolated β-bridgetrans-117.1144.1-178.6-59.8176.4000112.4R171 E347 Q354 V355 F481R171-L349 PolarHBondContact NH2-O 3.23Å; E347-L349 PolarHBondContact O-N 3.29Å; L349-Q354 CarbonylContact C-O 3.59Å; L349-Q354 WeakPolarHBondContact CA-O 3.22Å; L349-V355 HydrophobicContact CD2-CB 4.46Å; L349-V355 HydrophobicContact CD2-CG2 3.77Å; L349-F481 HydrophobicContact CD1-CD1 3.88Å; L349-F481 HydrophobicContact CD1-CE1 3.97Å; L349-F481 HydrophobicContact CD2-CD1 4.45Å; L349-F481 HydrophobicContact CD2-CE1 3.69Å; L349-F481 HydrophobicContact CD2-CZ 4.45Å; L349-F481 HydrophobicContact CG-CD1 4.16Å; L349-F481 HydrophobicContact CG-CE1 3.82Å
350T73.4Confident86Confident30 Ų3038.2 Ų38.218%0.18424%0.238CC..  trans-65.5167.616552.70000113.3A352 G353 Q354 H356T350-A352 PolarHBondContact O-N 3.5Å; T350-A352 PolarHBondContact OG1-N 3.38Å; T350-G353 PolarHBondContact O-N 3.44Å; T350-G353 PolarHBondContact OG1-N 2.96Å; T350-G353 VanDerWaalsContact OG1-N 3.09Å; T350-Q354 HydrophobicContact CG2-CB 4.31Å; T350-Q354 PolarHBondContact N-O 3.05Å; T350-Q354 WeakPolarHBondContact OG1-CB 3.25Å; T350-Q354 PolarHBondContact OG1-N 2.8Å; T350-Q354 PolarHBondContact OG1-O 2.95Å; T350-H356 WeakPolarHBondContact CG2-CD2 2.98Å; T350-H356 WeakPolarHBondContact CG2-CE1 3.42Å; T350-H356 VanDerWaalsContact CG2-CG 3.46Å; T350-H356 WeakPolarHBondContact CG2-ND1 3.42Å; T350-H356 WeakPolarHBondContact CG2-NE2 3.29Å
351A66.3Low85.9Confident106 Ų10639.2 Ų39.288%0.87625%0.248SC*.THydrogen-bonded Turntrans-55.1-27.7162.400000113.5G353A351-G353 VanDerWaalsContact C-N 3.35Å
352A68.6Low85.8Confident83 Ų8344.4 Ų44.469%0.68628%0.275SS*.THydrogen-bonded Turntrans-87.10.6176.100000113.7T350T350-A352 PolarHBondContact O-N 3.5Å; T350-A352 PolarHBondContact OG1-N 3.38Å
353G71.1Confident85.8Confident51 Ų5146.5 Ų46.553%0.52628%0.283SS..SBendtrans81.36.9178.800000115.6T350 A351T350-G353 PolarHBondContact O-N 3.44Å; T350-G353 PolarHBondContact OG1-N 2.96Å; T350-G353 VanDerWaalsContact OG1-N 3.09Å; A351-G353 VanDerWaalsContact C-N 3.35Å
354Q74.9Confident85.8Confident132 Ų13248.7 Ų48.762%0.61729%0.293SS*.  trans-79.8142.6173.3-61.8176.3-28.500111.5L349 T350L349-Q354 CarbonylContact C-O 3.59Å; L349-Q354 WeakPolarHBondContact CA-O 3.22Å; T350-Q354 HydrophobicContact CG2-CB 4.31Å; T350-Q354 PolarHBondContact N-O 3.05Å; T350-Q354 WeakPolarHBondContact OG1-CB 3.25Å; T350-Q354 PolarHBondContact OG1-N 2.8Å; T350-Q354 PolarHBondContact OG1-O 2.95Å
355V76.6Confident85.8Confident92 Ų9248.8 Ų48.856%0.55829%0.293SS*.BIsolated β-bridgetrans-70129.9176.7-179.80000110.4E348 L349E348-V355 CarbonylContact O-C 3.58Å; E348-V355 WeakPolarHBondContact O-CA 3.36Å; L349-V355 HydrophobicContact CD2-CB 4.46Å; L349-V355 HydrophobicContact CD2-CG2 3.77Å
356H76.5Confident85.9Confident41 Ų4148.3 Ų48.319%0.1929%0.291CS..  trans-113.4-3-178.9-93.9-147.1000113.3L292 Y307 E348 T350L292-H356 HydrophobicContact CD1-CB 3.8Å; L292-H356 WeakPolarHBondContact CD1-O 3.36Å; Y307-H356 VanDerWaalsContact CD2-O 3.29Å; Y307-H356 WeakPolarHBondContact CD2-O 3.22Å; E348-H356 HydrophobicContact CG-CB 4.08Å; E348-H356 PolarHBondContact O-N 2.87Å; T350-H356 WeakPolarHBondContact CG2-CD2 2.98Å; T350-H356 WeakPolarHBondContact CG2-CE1 3.42Å; T350-H356 VanDerWaalsContact CG2-CG 3.46Å; T350-H356 WeakPolarHBondContact CG2-ND1 3.42Å; T350-H356 WeakPolarHBondContact CG2-NE2 3.29Å
357G78.8Confident86.1Confident20 Ų2047.2 Ų47.221%0.20629%0.285CS..  trans-72170.1-179.700000114.7H345H345-G357 WeakPolarHBondContact O-CA 3.33Å
358G91.3Very high86.4Confident9 Ų947.3 Ų47.39%0.09329%0.286CS..  trans-79.5-178.4170.400000114.5D44 Y307 A344 L346D44-G358 WeakPolarHBondContact OD2-CA 3.46Å; Y307-G358 WeakPolarHBondContact OH-CA 3.3Å; A344-G358 VanDerWaalsContact CB-CA 3.48Å; L346-G358 WeakPolarHBondContact CD2-O 3.47Å
359W94.5Very high86.9Confident125 Ų12547 Ų4747%0.47329%0.285SS..  trans-117.9126.8-178.4-179.449.2000111.6G41 G43 D44 N50 G361G41-W359 CarbonylContact C-O 3.55Å; G41-W359 WeakPolarHBondContact CA-O 3.45Å; G43-W359 CarbonylContact C-O 3.59Å; G43-W359 WeakPolarHBondContact CA-O 3.27Å; G43-W359 PolarHBondContact N-O 2.74Å; G43-W359 WeakPolarHBondContact O-CZ3 3.33Å; D44-W359 PolarHBondContact N-O 3Å; D44-W359 WeakPolarHBondContact OD1-CB 3.28Å; D44-W359 PolarHBondContact OD1-N 3.2Å; D44-W359 PolarHBondContact OD2-N 3.47Å; N50-W359 HydrophobicContact CB-CZ3 4.43Å; W359-G361 VanDerWaalsContact C-N 3.34Å; W359-G361 VanDerWaalsContact CZ2-CA 3.45Å; W359-G361 PolarHBondContact NE1-O 3.2Å
360N97.1Very high87.7Confident4 Ų444.5 Ų44.52%0.02127%0.271CS..  trans-95.121.9178.5-61-42.3000112.8G41 A344 I362 Y363 A365 G366 G373G41-N360 WeakPolarHBondContact CA-OD1 3.38Å; A344-N360 WeakPolarHBondContact CB-OD1 3.46Å; A344-N360 PolarHBondContact N-OD1 3.11Å; N360-I362 PolarHBondContact O-N 3.02Å; N360-Y363 WeakPolarHBondContact O-CB 3.32Å; N360-Y363 WeakPolarHBondContact O-CD2 3.13Å; N360-Y363 PolarHBondContact O-N 2.03Å; N360-Y363 VanDerWaalsContact O-N 3.13Å; N360-A365 PolarHBondContact ND2-O 3.16Å; N360-G366 WeakPolarHBondContact ND2-CA 3.45Å; N360-G373 PolarHBondContact ND2-O 2.93Å; N360-G373 PolarHBondContact OD1-O 3.4Å
361G95.8Very high88.9Confident22 Ų2243.3 Ų43.323%0.22726%0.264CS..THydrogen-bonded Turntrans67.4-133.9175.500000113.2W359 Y363W359-G361 VanDerWaalsContact C-N 3.34Å; W359-G361 VanDerWaalsContact CZ2-CA 3.45Å; W359-G361 PolarHBondContact NE1-O 3.2Å; G361-Y363 VanDerWaalsContact C-N 3.26Å
362I96.7Very high90.4Very high109 Ų10938.3 Ų38.356%0.55922%0.222SC*.THydrogen-bonded Turntrans-79.3-9.3175.266176.3000113.1N360 P508 S509N360-I362 PolarHBondContact O-N 3.02Å; I362-P508 HydrophobicContact CD1-CB 4.05Å; I362-P508 HydrophobicContact CD1-CG 3.64Å; I362-S509 WeakPolarHBondContact O-CA 3.34Å; I362-S509 VanDerWaalsContact O-CB 3.28Å; I362-S509 WeakPolarHBondContact O-CB 3.48Å
363Y98.2Very high91.8Very high44 Ų4434.3 Ų34.317%0.17319%0.189CC..SBendtrans-81.8144.9-170.7-54.9-71.5000111.2I42 N360 G361 E372 R376 P508I42-Y363 HydrophobicContact CD1-CE2 3.92Å; I42-Y363 HydrophobicContact CG1-CE2 4.29Å; I42-Y363 HydrophobicContact CG2-CD2 3.32Å; I42-Y363 HydrophobicContact CG2-CE2 3.58Å; I42-Y363 HydrophobicContact CG2-CG 4.43Å; N360-Y363 WeakPolarHBondContact O-CB 3.32Å; N360-Y363 WeakPolarHBondContact O-CD2 3.13Å; N360-Y363 PolarHBondContact O-N 2.03Å; N360-Y363 VanDerWaalsContact O-N 3.13Å; G361-Y363 VanDerWaalsContact C-N 3.26Å; Y363-E372 HydrophobicContact CD1-CB 3.64Å; Y363-E372 HydrophobicContact CD1-CG 4.26Å; Y363-E372 HydrophobicContact CG-CB 4.04Å; Y363-R376 WeakPolarHBondContact OH-CD 3.46Å; Y363-R376 PolarHBondContact OH-NH1 2.92Å; Y363-P508 HydrophobicContact CD1-CB 4.39Å; Y363-P508 WeakPolarHBondContact CD1-O 3.48Å; Y363-P508 HydrophobicContact CE1-CB 3.93Å
364K97.8Very high93.1Very high45 Ų4531.9 Ų31.920%0.19616%0.164CC..  trans-77.7139.2-173.5-174.4170.3-177.9-179.10112.3W371 G373 T478 S509 E510K364-W371 HydrophobicContact CB-CB 4.17Å; K364-W371 HydrophobicContact CB-CG 4.48Å; K364-W371 HydrophobicContact CD-CD2 3.79Å; K364-W371 HydrophobicContact CD-CE3 3.72Å; K364-W371 HydrophobicContact CD-CG 4.31Å; K364-W371 HydrophobicContact CD-CH2 4.35Å; K364-W371 HydrophobicContact CD-CZ2 4.4Å; K364-W371 HydrophobicContact CD-CZ3 4.02Å; K364-W371 HydrophobicContact CG-CB 4.31Å; K364-W371 HydrophobicContact CG-CD2 4.14Å; K364-W371 HydrophobicContact CG-CE3 4.39Å; K364-W371 HydrophobicContact CG-CG 4.13Å; K364-W371 WeakPolarHBondContact O-CB 3.3Å; K364-G373 VanDerWaalsContact O-CA 3.23Å; K364-G373 WeakPolarHBondContact O-CA 3.13Å; K364-G373 PolarHBondContact O-N 2.92Å; K364-T478 HydrophobicContact CG-CG2 3.9Å; K364-S509 WeakPolarHBondContact CB-O 3.03Å; K364-E510 HydrophobicContact CB-CB 4.42Å; K364-E510 HydrophobicContact CD-CB 4.11Å; K364-E510 WeakPolarHBondContact CD-O 3.3Å; K364-E510 PolarHBondContact NZ-O 3.33Å
365A97.1Very high94.2Very high2 Ų225.6 Ų25.62%0.01714%0.135CC..  trans56.3-155.1176.300000113.5L346 N360 T369 W371 G373 F472 T478L346-A365 VanDerWaalsContact CD1-C 3.4Å; L346-A365 WeakPolarHBondContact CD1-O 3.34Å; N360-A365 PolarHBondContact ND2-O 3.16Å; A365-T369 HydrophobicContact CB-CG2 4.21Å; A365-W371 HydrophobicContact CB-CB 3.95Å; A365-W371 HydrophobicContact CB-CG 4.09Å; A365-G373 WeakPolarHBondContact O-CA 3.46Å; A365-F472 HydrophobicContact CB-CE1 4.23Å; A365-F472 HydrophobicContact CB-CZ 3.95Å; A365-T478 WeakPolarHBondContact CA-O 3.36Å; A365-T478 WeakPolarHBondContact CB-O 3.04Å
366G97.1Very high95.3Very high0 Ų021.9 Ų21.90%011%0.111CC..  trans-159.7-158.5-171.500000113.4A344 N360 T369 G373 G374A344-G366 CarbonylContact O-C 3.54Å; A344-G366 VanDerWaalsContact O-CA 3.29Å; A344-G366 WeakPolarHBondContact O-CA 3.5Å; N360-G366 WeakPolarHBondContact ND2-CA 3.45Å; G366-T369 PolarHBondContact O-N 3.12Å; G366-T369 PolarHBondContact O-OG1 2.79Å; G366-G373 WeakPolarHBondContact CA-O 3.37Å; G366-G374 WeakPolarHBondContact O-CA 3.36Å
367K97.1Very high96.3Very high11 Ų1119.9 Ų19.95%0.04810%0.102CC..THydrogen-bonded Turntrans-35.6142.9172.9-176.1179.1-171.4167.20111.3D39 L77 H289 Q342 A344 H345 T369D39-K367 VanDerWaalsContact OD1-CD 3.3Å; D39-K367 WeakPolarHBondContact OD1-CD 3.4Å; D39-K367 VanDerWaalsContact OD1-CE 3.22Å; D39-K367 WeakPolarHBondContact OD1-CE 3.04Å; D39-K367 IonicContact OD1-NZ 2.61Å; D39-K367 PolarHBondContact OD1-NZ 3.01Å; D39-K367 IonicContact OD2-NZ 2.95Å; D39-K367 PolarHBondContact OD2-NZ 3Å; L77-K367 HydrophobicContact CD2-CG 4.33Å; H289-K367 PolarHBondContact CD2-NZ 3.26Å; H289-K367 VanDerWaalsContact CD2-NZ 3.26Å; H289-K367 PolarHBondContact NE2-NZ 2.65Å; Q342-K367 HydrophobicContact CG-CG 4.21Å; A344-K367 PolarHBondContact O-N 3.11Å; H345-K367 HydrophobicContact CB-CB 4.19Å; H345-K367 HydrophobicContact CB-CD 3.76Å; K367-T369 VanDerWaalsContact C-N 3.29Å; K367-T369 PolarHBondContact O-N 2.73Å
368S96.1Very high97.3Very high4 Ų419 Ų193%0.0289%0.092CC..THydrogen-bonded Turntrans71.95.9-176.676.20000116.8S76 C486S76-S368 PolarHBondContact O-N 2.93Å; S368-C486 WeakPolarHBondContact CB-O 3.37Å; S368-C486 PolarHBondContact OG-N 2.91Å
369T97.4Very high97.6Very high2 Ų218.5 Ų18.51%0.0129%0.087CC..SBendtrans-126153.3175.277.80000111.6S76 A365 G366 K367 W371 G374 P470 F472 C486S76-T369 WeakPolarHBondContact CB-O 3.44Å; S76-T369 PolarHBondContact OG-N 2.95Å; S76-T369 PolarHBondContact OG-O 3.41Å; A365-T369 HydrophobicContact CB-CG2 4.21Å; G366-T369 PolarHBondContact O-N 3.12Å; G366-T369 PolarHBondContact O-OG1 2.79Å; K367-T369 VanDerWaalsContact C-N 3.29Å; K367-T369 PolarHBondContact O-N 2.73Å; T369-W371 VanDerWaalsContact C-N 3.33Å; T369-G374 WeakPolarHBondContact O-CA 3.41Å; T369-P470 HydrophobicContact CG2-CG 4.07Å; T369-F472 HydrophobicContact CG2-CE1 4.48Å; T369-C486 HydrophobicContact CG2-CB 3.78Å; T369-C486 VanDerWaalsContact CG2-SG 3.54Å
370N98.4Very high97.8Very high2 Ų212.6 Ų12.61%0.0117%0.065CC..  trans-95.117.1169.7-63.5-60.1000112.9I375 H443 Y444 C445 N450 K464 F466N370-I375 HydrophobicContact CB-CG2 4.45Å; N370-I375 WeakPolarHBondContact OD1-CG2 3.39Å; N370-H443 HydrophobicContact CB-CB 3.99Å; N370-Y444 PolarHBondContact ND2-O 2.88Å; N370-Y444 PolarHBondContact OD1-O 2.86Å; N370-C445 PolarHBondContact ND2-N 3.14Å; N370-N450 VanDerWaalsContact CB-OD1 3.28Å; N370-N450 WeakPolarHBondContact CB-OD1 3.29Å; N370-N450 VanDerWaalsContact ND2-CB 3.34Å; N370-N450 WeakPolarHBondContact ND2-CB 3.5Å; N370-N450 PolarHBondContact ND2-OD1 3.13Å; N370-K464 VanDerWaalsContact O-CE 3.24Å; N370-K464 WeakPolarHBondContact O-CE 3.2Å; N370-K464 PolarHBondContact O-NZ 2.83Å; N370-F466 HydrophobicContact CB-CE1 4.28Å; N370-F466 WeakPolarHBondContact O-CZ 3.35Å
371W98.6Very high97.9Very high6 Ų612.4 Ų12.42%0.0236%0.064CC..SBendtrans-63155.7158.9-63.9111.6000109K364 A365 T369 G373 G374 I375 F466 T469 F472 L500 F502 E510K364-W371 HydrophobicContact CB-CB 4.17Å; K364-W371 HydrophobicContact CB-CG 4.48Å; K364-W371 HydrophobicContact CD-CD2 3.79Å; K364-W371 HydrophobicContact CD-CE3 3.72Å; K364-W371 HydrophobicContact CD-CG 4.31Å; K364-W371 HydrophobicContact CD-CH2 4.35Å; K364-W371 HydrophobicContact CD-CZ2 4.4Å; K364-W371 HydrophobicContact CD-CZ3 4.02Å; K364-W371 HydrophobicContact CG-CB 4.31Å; K364-W371 HydrophobicContact CG-CD2 4.14Å; K364-W371 HydrophobicContact CG-CE3 4.39Å; K364-W371 HydrophobicContact CG-CG 4.13Å; K364-W371 WeakPolarHBondContact O-CB 3.3Å; A365-W371 HydrophobicContact CB-CB 3.95Å; A365-W371 HydrophobicContact CB-CG 4.09Å; T369-W371 VanDerWaalsContact C-N 3.33Å; W371-G373 PolarHBondContact O-N 3.02Å; W371-G373 VanDerWaalsContact O-N 3.08Å; W371-G374 PolarHBondContact O-N 3.35Å; W371-I375 PolarHBondContact O-N 3.03Å; W371-F466 HydrophobicContact CD2-CE1 4.29Å; W371-F466 HydrophobicContact CD2-CE2 4.49Å; W371-F466 AromaticContact CD2-CZ 3.89Å; W371-F466 HydrophobicContact CD2-CZ 3.89Å; W371-F466 HydrophobicContact CE3-CE1 4.24Å; W371-F466 AromaticContact CE3-CE2 3.67Å; W371-F466 HydrophobicContact CE3-CE2 3.67Å; W371-F466 AromaticContact CE3-CZ 3.45Å; W371-F466 HydrophobicContact CE3-CZ 3.45Å; W371-F466 VanDerWaalsContact CE3-CZ 3.45Å; W371-F466 HydrophobicContact CG-CZ 4.47Å; W371-F466 HydrophobicContact CH2-CE2 4.3Å; W371-F466 HydrophobicContact CZ3-CD2 4.13Å; W371-F466 AromaticContact CZ3-CE2 3.55Å; W371-F466 HydrophobicContact CZ3-CE2 3.55Å; W371-F466 AromaticContact CZ3-CZ 3.8Å; W371-F466 HydrophobicContact CZ3-CZ 3.8Å; W371-T469 HydrophobicContact CH2-CG2 3.94Å; W371-T469 HydrophobicContact CZ2-CG2 3.49Å; W371-T469 VanDerWaalsContact CZ2-CG2 3.49Å; W371-F472 AromaticContact CD1-CZ 3.57Å; W371-F472 AromaticContact NE1-CE2 3.82Å; W371-F472 AromaticContact NE1-CZ 3.26Å; W371-F472 VanDerWaalsContact NE1-CZ 3.26Å; W371-L500 HydrophobicContact CH2-CD2 4.12Å; W371-F502 AromaticContact CH2-CE2 3.91Å; W371-F502 HydrophobicContact CH2-CE2 3.91Å; W371-F502 AromaticContact CH2-CZ 3.77Å; W371-F502 HydrophobicContact CH2-CZ 3.77Å; W371-F502 HydrophobicContact CZ3-CD2 4.43Å; W371-F502 HydrophobicContact CZ3-CE1 4.45Å; W371-F502 AromaticContact CZ3-CE2 3.61Å; W371-F502 HydrophobicContact CZ3-CE2 3.61Å; W371-F502 AromaticContact CZ3-CZ 3.63Å; W371-F502 HydrophobicContact CZ3-CZ 3.63Å; W371-E510 HydrophobicContact CE3-CB 3.74Å; W371-E510 VanDerWaalsContact CE3-CD 3.48Å; W371-E510 HydrophobicContact CE3-CG 4.2Å; W371-E510 HydrophobicContact CZ3-CB 3.71Å; W371-E510 HydrophobicContact CZ3-CG 4.4Å
372E98.8Very high98Very high0 Ų011.3 Ų11.30%05%0.053CC..Hα-helixtrans-53.4-35.5-175.2-72.4-57.399.300111.7Y363 G374 I375 R376 R453 K464 L504 E510Y363-E372 HydrophobicContact CD1-CB 3.64Å; Y363-E372 HydrophobicContact CD1-CG 4.26Å; Y363-E372 HydrophobicContact CG-CB 4.04Å; E372-G374 PolarHBondContact O-N 3.27Å; E372-I375 PolarHBondContact O-N 3.31Å; E372-R376 HydrophobicContact CB-CB 4.4Å; E372-R376 WeakPolarHBondContact O-CA 3.11Å; E372-R376 WeakPolarHBondContact O-CB 2.84Å; E372-R376 PolarHBondContact O-N 2.74Å; E372-R376 IonicContact OE2-CZ 3.47Å; E372-R376 IonicContact OE2-NE 2.74Å; E372-R376 PolarHBondContact OE2-NE 3.16Å; E372-R376 IonicContact OE2-NH2 3.42Å; E372-R376 PolarHBondContact OE2-NH2 2.6Å; E372-R453 IonicContact OE1-CZ 3.48Å; E372-R453 IonicContact OE1-NH2 3.7Å; E372-R453 PolarHBondContact OE1-NH2 3.07Å; E372-R453 IonicContact OE2-CZ 3.61Å; E372-R453 IonicContact OE2-NH2 3.48Å; E372-R453 PolarHBondContact OE2-NH2 3.33Å; E372-K464 IonicContact OE1-NZ 2.75Å; E372-K464 PolarHBondContact OE1-NZ 2.85Å; E372-L504 HydrophobicContact CG-CD1 4.34Å; E372-L504 HydrophobicContact CG-CD2 3.99Å; E372-E510 WeakPolarHBondContact CB-OE2 3.3Å; E372-E510 HydrophobicContact CG-CG 4.18Å; E372-E510 WeakPolarHBondContact CG-OE2 3.47Å; E372-E510 PolarHBondContact N-OE2 3.18Å
373G98.3Very high98.1Very high0 Ų07 Ų70%03%0.03CC..Hα-helixtrans-67.4-17.5178.500000114.3G343 N360 K364 A365 G366 W371G343-G373 WeakPolarHBondContact CA-O 3.14Å; N360-G373 PolarHBondContact ND2-O 2.93Å; N360-G373 PolarHBondContact OD1-O 3.4Å; K364-G373 VanDerWaalsContact O-CA 3.23Å; K364-G373 WeakPolarHBondContact O-CA 3.13Å; K364-G373 PolarHBondContact O-N 2.92Å; A365-G373 WeakPolarHBondContact O-CA 3.46Å; G366-G373 WeakPolarHBondContact CA-O 3.37Å; W371-G373 PolarHBondContact O-N 3.02Å; W371-G373 VanDerWaalsContact O-N 3.08Å
374G98Very high98Very high0 Ų06.3 Ų6.30%03%0.031CC..Hα-helixtrans-94-24.1176.300000115.2G343 G366 T369 W371 E372G343-G374 PolarHBondContact N-O 3.11Å; G343-G374 VanDerWaalsContact N-O 3.11Å; G366-G374 WeakPolarHBondContact O-CA 3.36Å; T369-G374 WeakPolarHBondContact O-CA 3.41Å; W371-G374 PolarHBondContact O-N 3.35Å; E372-G374 PolarHBondContact O-N 3.27Å
375I98.4Very high97.8Very high0 Ų08 Ų80%06%0.06CC..Hα-helixtrans-117.7-27-176.457.1168.2000113.8V72 A73 N370 W371 E372 V377 H443V72-I375 CarbonylContact C-O 3.53Å; V72-I375 WeakPolarHBondContact CA-O 3.38Å; V72-I375 HydrophobicContact CG1-CD1 4.38Å; V72-I375 HydrophobicContact CG1-CG1 4.39Å; A73-I375 PolarHBondContact N-O 2.98Å; N370-I375 HydrophobicContact CB-CG2 4.45Å; N370-I375 WeakPolarHBondContact OD1-CG2 3.39Å; W371-I375 PolarHBondContact O-N 3.03Å; E372-I375 PolarHBondContact O-N 3.31Å; I375-V377 PolarHBondContact O-N 3.14Å; I375-H443 WeakPolarHBondContact CD1-ND1 3.34Å
376R98.6Very high97.7Very high13 Ų1312.4 Ų12.45%0.0498%0.081CC..BIsolated β-bridgetrans-78.8123.8177.2-163-176.7-79.8-128.91.6108.8I42 T69 H70 H71 V72 Y363 E372I42-R376 HydrophobicContact CD1-CG 3.68Å; T69-R376 PolarHBondContact O-NH1 3.2Å; H70-R376 VanDerWaalsContact CD2-CZ 3.45Å; H70-R376 PolarHBondContact CD2-NH2 2.91Å; H70-R376 PolarHBondContact CE1-NH2 2.69Å; H70-R376 VanDerWaalsContact CE1-NH2 3.32Å; H70-R376 PolarHBondContact NE2-NH2 2.73Å; H71-R376 WeakPolarHBondContact O-CA 3.42Å; H71-R376 WeakPolarHBondContact O-CG 3.39Å; V72-R376 HydrophobicContact CG1-CB 4.46Å; Y363-R376 WeakPolarHBondContact OH-CD 3.46Å; Y363-R376 PolarHBondContact OH-NH1 2.92Å; E372-R376 HydrophobicContact CB-CB 4.4Å; E372-R376 WeakPolarHBondContact O-CA 3.11Å; E372-R376 WeakPolarHBondContact O-CB 2.84Å; E372-R376 PolarHBondContact O-N 2.74Å; E372-R376 IonicContact OE2-CZ 3.47Å; E372-R376 IonicContact OE2-NE 2.74Å; E372-R376 PolarHBondContact OE2-NE 3.16Å; E372-R376 IonicContact OE2-NH2 3.42Å; E372-R376 PolarHBondContact OE2-NH2 2.6Å
377V98.8Very high97.7Very high0 Ų012.6 Ų12.60%08%0.082CC..  trans-130158.7-171.6-680000110.1H71 A73 Q342 I375 G379H71-V377 PolarHBondContact O-N 2.69Å; A73-V377 HydrophobicContact CB-CG1 4.19Å; Q342-V377 VanDerWaalsContact C-CG1 3.47Å; I375-V377 PolarHBondContact O-N 3.14Å; V377-G379 PolarHBondContact O-N 2.74Å
378P98.6Very high97.6Very high0 Ų014.9 Ų14.90%010%0.098CC..  trans-54.2141.1165.9-24.835.6000111.1L40 I42 L45 Y48 T339L40-P378 HydrophobicContact CD2-CG 4.05Å; I42-P378 HydrophobicContact CB-CG 4.47Å; L45-P378 HydrophobicContact CD1-CB 3.71Å; L45-P378 HydrophobicContact CD1-CG 3.77Å; L45-P378 HydrophobicContact CG-CG 4.43Å; Y48-P378 HydrophobicContact CD2-CB 4.44Å; Y48-P378 HydrophobicContact CE2-CB 3.87Å; T339-P378 VanDerWaalsContact CA-O 3.25Å; T339-P378 WeakPolarHBondContact CA-O 3.43Å; T339-P378 VanDerWaalsContact CB-O 3.31Å; T339-P378 WeakPolarHBondContact CB-O 3.09Å; T339-P378 PolarHBondContact OG1-O 3.5Å
379G98.7Very high97.6Very high0 Ų018.6 Ų18.60%012%0.124CC..EExtended strand (participates in β ladder)trans-141.9103.1172.300000108.6Y48 L68 V377Y48-G379 PolarHBondContact OH-N 2.74Å; Y48-G379 PolarHBondContact OH-O 2.93Å; L68-G379 VanDerWaalsContact CB-O 3.32Å; L68-G379 WeakPolarHBondContact CB-O 3.49Å; L68-G379 WeakPolarHBondContact CG-O 3.43Å; L68-G379 PolarHBondContact N-O 3.32Å; V377-G379 PolarHBondContact O-N 2.74Å
380I98.9Very high97.5Very high0 Ų021.3 Ų21.30%015%0.152CC..EExtended strand (participates in β ladder)trans-120.6125.7-178.2-56.8167.9000108.1L45 Y48 I58 L61 A62 V66 Y337 L338L45-I380 HydrophobicContact CD1-CD1 4.25Å; Y48-I380 HydrophobicContact CE2-CD1 4.18Å; Y48-I380 HydrophobicContact CE2-CG1 4.07Å; I58-I380 HydrophobicContact CG2-CD1 3.6Å; L61-I380 HydrophobicContact CB-CG2 4.39Å; L61-I380 HydrophobicContact CD2-CG2 4.13Å; L61-I380 HydrophobicContact CG-CG2 3.79Å; A62-I380 HydrophobicContact CB-CD1 4.11Å; A62-I380 HydrophobicContact CB-CG1 4.36Å; A62-I380 HydrophobicContact CB-CG2 4.03Å; V66-I380 WeakPolarHBondContact O-CA 3.26Å; Y337-I380 CarbonylContact C-O 3.57Å; Y337-I380 VanDerWaalsContact CA-O 3.3Å; Y337-I380 WeakPolarHBondContact CA-O 3.48Å; L338-I380 HydrophobicContact CB-CB 4.34Å; L338-I380 HydrophobicContact CD2-CD1 4.27Å; L338-I380 PolarHBondContact N-O 3.19Å; L338-I380 PolarHBondContact O-N 2.99Å
381L98.8Very high97.4Very high0 Ų024.5 Ų24.50%016%0.164CC..EExtended strand (participates in β ladder)trans-123.4131.6176.4-71.188.6000110.2G65 V66 L68 L335 L336 Y337 I387 L402 L429G65-L381 CarbonylContact C-O 3.58Å; G65-L381 VanDerWaalsContact CA-O 3.3Å; G65-L381 WeakPolarHBondContact CA-O 3.22Å; V66-L381 PolarHBondContact N-O 3.45Å; V66-L381 PolarHBondContact O-N 3.18Å; L68-L381 HydrophobicContact CD1-CD1 3.63Å; L68-L381 HydrophobicContact CG-CD1 4.12Å; L335-L381 HydrophobicContact CD1-CD2 4.47Å; L336-L381 CarbonylContact O-C 3.52Å; L336-L381 VanDerWaalsContact O-CA 3.27Å; L336-L381 WeakPolarHBondContact O-CA 3.43Å; Y337-L381 HydrophobicContact CD2-CD1 3.7Å; Y337-L381 HydrophobicContact CD2-CD2 4.37Å; Y337-L381 HydrophobicContact CD2-CG 3.77Å; Y337-L381 HydrophobicContact CE2-CD1 4.04Å; L381-I387 HydrophobicContact CB-CD1 4.35Å; L381-L402 HydrophobicContact CD2-CD2 4.48Å; L381-L429 HydrophobicContact CB-CD2 4.23Å; L381-L429 HydrophobicContact CD1-CD2 4.34Å; L381-L429 HydrophobicContact CD2-CD1 3.6Å; L381-L429 HydrophobicContact CD2-CD2 4.16Å; L381-L429 HydrophobicContact CG-CD2 4.48Å
382S98.5Very high97.4Very high0 Ų029.5 Ų29.50%019%0.187CC..EExtended strand (participates in β ladder)trans-135.6132.2175.8-179.70000110.2L61 L336L61-S382 VanDerWaalsContact CD1-CB 3.43Å; L336-S382 PolarHBondContact N-O 2.87Å; L336-S382 PolarHBondContact O-N 3.2Å
383W98.1Very high97.4Very high18 Ų1829.7 Ų29.77%0.06819%0.188CC..  trans-150.692.5171.7-171.4-7.3000108.3P30 E332 L335 G385 Q386 I387 L409 M426P30-W383 HydrophobicContact CB-CH2 3.54Å; P30-W383 HydrophobicContact CB-CZ2 3.41Å; P30-W383 VanDerWaalsContact CB-CZ2 3.41Å; P30-W383 HydrophobicContact CB-CZ3 4.43Å; P30-W383 HydrophobicContact CG-CH2 3.65Å; P30-W383 HydrophobicContact CG-CZ2 4.05Å; P30-W383 HydrophobicContact CG-CZ3 4.45Å; E332-W383 VanDerWaalsContact O-CD1 3.3Å; E332-W383 PolarHBondContact O-NE1 3.23Å; L335-W383 HydrophobicContact CB-CD2 4.15Å; L335-W383 HydrophobicContact CB-CE3 3.9Å; L335-W383 HydrophobicContact CB-CG 4.5Å; L335-W383 HydrophobicContact CB-CZ3 4.47Å; L335-W383 HydrophobicContact CD1-CB 4.03Å; L335-W383 HydrophobicContact CD1-CE3 4.11Å; L335-W383 HydrophobicContact CG-CE3 4.43Å; W383-G385 PolarHBondContact O-N 3.42Å; W383-Q386 HydrophobicContact CB-CB 4.2Å; W383-Q386 HydrophobicContact CD2-CB 3.61Å; W383-Q386 HydrophobicContact CD2-CG 3.72Å; W383-Q386 VanDerWaalsContact CE2-CG 3.4Å; W383-Q386 HydrophobicContact CE3-CB 3.98Å; W383-Q386 HydrophobicContact CE3-CG 4.32Å; W383-Q386 HydrophobicContact CG-CB 3.7Å; W383-Q386 HydrophobicContact CG-CG 3.99Å; W383-Q386 HydrophobicContact CH2-CG 4.34Å; W383-Q386 HydrophobicContact CZ2-CB 4.45Å; W383-Q386 HydrophobicContact CZ2-CG 3.74Å; W383-Q386 PolarHBondContact O-N 3.44Å; W383-I387 HydrophobicContact CB-CB 4.36Å; W383-I387 HydrophobicContact CB-CD1 3.8Å; W383-I387 HydrophobicContact CB-CG1 3.98Å; W383-I387 PolarHBondContact O-N 2.55Å; W383-L409 HydrophobicContact CE3-CD1 4.43Å; W383-L409 HydrophobicContact CH2-CD1 4.45Å; W383-L409 HydrophobicContact CH2-CD2 3.96Å; W383-L409 HydrophobicContact CZ3-CD1 3.64Å; W383-L409 HydrophobicContact CZ3-CD2 3.63Å; W383-L409 HydrophobicContact CZ3-CG 4.23Å; W383-M426 HydrophobicContact CE3-CE 4.37Å; W383-M426 HydrophobicContact CZ3-CE 4.22Å
384P96.4Very high97.3Very high30 Ų3035.1 Ų35.120%0.19522%0.217CC..THydrogen-bonded Turntrans-54.5131-175.7-30.439000112.2R331 E332 Q386R331-P384 HydrophobicContact CG-CG 4.11Å; E332-P384 HydrophobicContact CG-CB 4.46Å; P384-Q386 PolarHBondContact O-N 3.13Å
385G92.3Very high97.3Very high79 Ų7936.1 Ų36.181%0.81422%0.222SC*.THydrogen-bonded Turntrans82.2-15.1-177.400000115.4W383W383-G385 PolarHBondContact O-N 3.42Å
386Q96.1Very high97.3Very high95 Ų9536.1 Ų36.144%0.44422%0.222SC..THydrogen-bonded Turntrans-111.7-32.5177.4-61.5-58-34.300113.5W383 P384 Q430W383-Q386 HydrophobicContact CB-CB 4.2Å; W383-Q386 HydrophobicContact CD2-CB 3.61Å; W383-Q386 HydrophobicContact CD2-CG 3.72Å; W383-Q386 VanDerWaalsContact CE2-CG 3.4Å; W383-Q386 HydrophobicContact CE3-CB 3.98Å; W383-Q386 HydrophobicContact CE3-CG 4.32Å; W383-Q386 HydrophobicContact CG-CB 3.7Å; W383-Q386 HydrophobicContact CG-CG 3.99Å; W383-Q386 HydrophobicContact CH2-CG 4.34Å; W383-Q386 HydrophobicContact CZ2-CB 4.45Å; W383-Q386 HydrophobicContact CZ2-CG 3.74Å; W383-Q386 PolarHBondContact O-N 3.44Å; P384-Q386 PolarHBondContact O-N 3.13Å; Q386-Q430 WeakPolarHBondContact O-CG 3.48Å; Q386-Q430 PolarHBondContact O-NE2 2.79Å; Q386-Q430 VanDerWaalsContact O-NE2 3.08Å
387I96.6Very high97.3Very high5 Ų535.5 Ų35.53%0.02622%0.22CC..SBendtrans-115.3132.9177.1-64.4174.6000108.5V66 L335 L381 W383 L429V66-I387 HydrophobicContact CB-CG2 4.18Å; V66-I387 HydrophobicContact CG2-CG2 3.38Å; L335-I387 HydrophobicContact CD1-CD1 3.89Å; L381-I387 HydrophobicContact CB-CD1 4.35Å; W383-I387 HydrophobicContact CB-CB 4.36Å; W383-I387 HydrophobicContact CB-CD1 3.8Å; W383-I387 HydrophobicContact CB-CG1 3.98Å; W383-I387 PolarHBondContact O-N 2.55Å; I387-L429 HydrophobicContact CD1-CB 4.33Å; I387-L429 HydrophobicContact CD1-CD1 4.11Å; I387-L429 HydrophobicContact CG1-CB 4.32Å
388P95.6Very high97.3Very high59 Ų5935.6 Ų35.638%0.38322%0.22SC..  trans-60.8135.2174.6-2132.3000112G65 L429G65-P388 CarbonylContact C-O 3.45Å; P388-L429 WeakPolarHBondContact CD-O 3.39Å
389S96.2Very high97.3Very high82 Ų8235.6 Ų35.657%0.57322%0.22SC*.THydrogen-bonded Turntrans-76.3148.1176.2-55.70000112.3E64 G65 R391E64-S389 WeakPolarHBondContact O-CB 3.32Å; E64-S389 PolarHBondContact O-OG 3.07Å; G65-S389 CarbonylContact O-C 3.55Å; S389-R391 VanDerWaalsContact C-N 3.29Å; S389-R391 PolarHBondContact O-N 3.04Å
390G95Very high97.3Very high58 Ų5835.6 Ų35.660%0.59822%0.22SC*.THydrogen-bonded Turntrans71.717.4172.500000114.7Q63 G65Q63-G390 WeakPolarHBondContact O-CA 3.36Å; Q63-G390 PolarHBondContact O-N 3.33Å; G65-G390 PolarHBondContact O-N 2.76Å
391R96.4Very high97.3Very high70 Ų7035.6 Ų35.626%0.26422%0.22SC..EExtended strand (participates in β ladder)trans-89.1143.4-177.6-178.2174.1-179.2-149.2-1.7111.3G65 V66 K67 S389 I393 L428 L429G65-R391 PolarHBondContact O-N 3.23Å; G65-R391 VanDerWaalsContact O-N 3.13Å; V66-R391 CarbonylContact C-O 3.52Å; V66-R391 VanDerWaalsContact CA-O 3.29Å; V66-R391 WeakPolarHBondContact CA-O 3.43Å; V66-R391 HydrophobicContact CG2-CB 3.97Å; V66-R391 HydrophobicContact CG2-CG 4.39Å; K67-R391 PolarHBondContact N-O 3.44Å; S389-R391 VanDerWaalsContact C-N 3.29Å; S389-R391 PolarHBondContact O-N 3.04Å; R391-I393 HydrophobicContact CG-CG1 4.33Å; R391-L428 PolarHBondContact NH1-O 2.94Å; R391-L428 PolarHBondContact NH2-O 2.74Å; R391-L429 PolarHBondContact NH1-O 3.35Å
392E98Very high97.3Very high110 Ų11035.6 Ų35.651%0.51422%0.22SC..EExtended strand (participates in β ladder)trans-111.2138.7171.3-164.7169.8119.500109.6K67 T69K67-E392 WeakPolarHBondContact CE-OE2 3.35Å; K67-E392 IonicContact NZ-OE2 3.13Å; K67-E392 PolarHBondContact NZ-OE2 2.96Å; K67-E392 WeakPolarHBondContact O-CA 3.28Å; T69-E392 VanDerWaalsContact CG2-CD 3.41Å; T69-E392 HydrophobicContact CG2-CG 3.49Å; T69-E392 VanDerWaalsContact CG2-CG 3.49Å; T69-E392 WeakPolarHBondContact CG2-OE1 3.33Å
393I98.4Very high97.3Very high5 Ų535.6 Ų35.63%0.02622%0.22CC..EExtended strand (participates in β ladder)trans-128.3122.8176.3-59-177.3000108.6V66 K67 L68 T69 R391 E395 L428 L429V66-I393 HydrophobicContact CG1-CB 4.37Å; V66-I393 HydrophobicContact CG1-CD1 3.63Å; V66-I393 HydrophobicContact CG1-CG1 3.79Å; V66-I393 HydrophobicContact CG2-CD1 4.44Å; K67-I393 PolarHBondContact O-N 2.92Å; L68-I393 CarbonylContact C-O 3.51Å; L68-I393 WeakPolarHBondContact CA-O 3.46Å; L68-I393 HydrophobicContact CD2-CB 3.87Å; L68-I393 HydrophobicContact CD2-CD1 4.36Å; L68-I393 HydrophobicContact CD2-CG2 4.26Å; T69-I393 PolarHBondContact N-O 3.45Å; T69-I393 PolarHBondContact OG1-O 2.99Å; R391-I393 HydrophobicContact CG-CG1 4.33Å; I393-E395 HydrophobicContact CG2-CB 3.88Å; I393-E395 HydrophobicContact CG2-CG 4.39Å; I393-L428 HydrophobicContact CD1-CD1 4.46Å; I393-L428 HydrophobicContact CD1-CG 4.01Å; I393-L428 HydrophobicContact CG2-CD1 4.08Å; I393-L428 HydrophobicContact CG2-CD2 4.04Å; I393-L428 HydrophobicContact CG2-CG 4.08Å; I393-L429 HydrophobicContact CD1-CD2 4.46Å
394D97.1Very high97.4Very high113 Ų11335.1 Ų35.160%0.60422%0.219SC*.  trans-102.4-0.5-17759.8-24.7000113.9T69 H70T69-D394 WeakPolarHBondContact OG1-CA 3.36Å; H70-D394 WeakPolarHBondContact CB-O 3.22Å; H70-D394 PolarHBondContact ND1-O 3.37Å
395E98.1Very high97.5Very high21 Ų2133.7 Ų33.710%0.09821%0.21CC..SBendtrans-64.6139.9173-75.8-67.211500112.5I393 T397 L428 R435 S436 H455I393-E395 HydrophobicContact CG2-CB 3.88Å; I393-E395 HydrophobicContact CG2-CG 4.39Å; E395-T397 PolarHBondContact O-N 3.44Å; E395-L428 HydrophobicContact CB-CD1 4.44Å; E395-L428 HydrophobicContact CB-CD2 4.24Å; E395-L428 HydrophobicContact CG-CD1 4.24Å; E395-R435 VanDerWaalsContact OE2-CA 3.32Å; E395-R435 WeakPolarHBondContact OE2-CA 3.47Å; E395-S436 PolarHBondContact OE2-N 3.33Å; E395-S436 PolarHBondContact OE2-OG 2.87Å; E395-H455 IonicContact OE1-NE2 3.41Å; E395-H455 PolarHBondContact OE1-NE2 3.24Å; E395-H455 IonicContact OE2-CD2 3.87Å; E395-H455 IonicContact OE2-NE2 2.69Å
396P98.5Very high97.8Very high1 Ų130 Ų301%0.00617%0.171CC..  trans-58.6121.4175.3-21.332.2000111.6S436 H438 L441 H455 V462P396-S436 WeakPolarHBondContact O-CB 3.38Å; P396-S436 PolarHBondContact O-OG 2.78Å; P396-H438 HydrophobicContact CB-CB 4.39Å; P396-H438 PolarHBondContact O-CD2 3.08Å; P396-L441 HydrophobicContact CB-CD1 3.91Å; P396-H455 HydrophobicContact CG-CB 4.01Å; P396-V462 HydrophobicContact CG-CG1 4.47Å; P396-V462 HydrophobicContact CG-CG2 4.26Å
397T98.9Very high97.9Very high0 Ų025.4 Ų25.40%015%0.15CC..EExtended strand (participates in β ladder)trans-133.3160.8177.2490000109.5H70 H71 V72 E395 L425 L428H70-T397 PolarHBondContact O-N 3.46Å; H70-T397 VanDerWaalsContact O-N 3.13Å; H71-T397 CarbonylContact C-O 3.59Å; H71-T397 WeakPolarHBondContact CA-O 3.48Å; H71-T397 WeakPolarHBondContact CA-OG1 3.46Å; H71-T397 WeakPolarHBondContact ND1-CB 3.27Å; H71-T397 PolarHBondContact ND1-OG1 2.85Å; V72-T397 VanDerWaalsContact CG2-O 3.24Å; V72-T397 WeakPolarHBondContact CG2-O 3.43Å; V72-T397 PolarHBondContact N-O 3.43Å; E395-T397 PolarHBondContact O-N 3.44Å; T397-L425 HydrophobicContact CG2-CD2 3.7Å; T397-L428 HydrophobicContact CG2-CD2 3.8Å
398S98.9Very high98Very high1 Ų130.3 Ų30.31%0.00717%0.173CC..EExtended strand (participates in β ladder)trans-127.9151.7-176.7-173.80000113.2H71 V72 M400 D401H71-S398 PolarHBondContact CE1-O 3.46Å; H71-S398 VanDerWaalsContact CE1-O 3.27Å; V72-S398 CarbonylContact O-C 3.44Å; V72-S398 WeakPolarHBondContact O-CA 3.34Å; V72-S398 PolarHBondContact O-OG 3.34Å; S398-M400 PolarHBondContact O-N 2.99Å; S398-M400 VanDerWaalsContact O-N 3.1Å; S398-M400 PolarHBondContact OG-N 3.34Å; S398-D401 PolarHBondContact N-OD2 3.31Å; S398-D401 WeakPolarHBondContact O-CB 3.36Å; S398-D401 VanDerWaalsContact O-CG 3.3Å; S398-D401 PolarHBondContact O-N 2.76Å
399N98.6Very high98.1Very high0 Ų029 Ų290%016%0.162CC..G310 helixtrans-54.3-26.6166.1-7510.4000112H71 V72 F85 Y337 T339 S340 D401 L402H71-N399 PolarHBondContact CD2-OD1 3.4Å; H71-N399 VanDerWaalsContact CD2-OD1 3.32Å; H71-N399 PolarHBondContact NE2-OD1 2.8Å; V72-N399 PolarHBondContact O-N 3.28Å; F85-N399 HydrophobicContact CD2-CB 4.28Å; F85-N399 WeakPolarHBondContact CD2-O 3.37Å; Y337-N399 PolarHBondContact OH-OD1 2.99Å; Y337-N399 VanDerWaalsContact OH-OD1 3.04Å; T339-N399 PolarHBondContact OG1-OD1 3.22Å; S340-N399 PolarHBondContact O-ND2 3.37Å; S340-N399 VanDerWaalsContact O-ND2 3.08Å; N399-D401 PolarHBondContact O-N 3.39Å; N399-L402 PolarHBondContact O-N 2.85Å
400M98.8Very high98.1Very high0 Ų025.1 Ų25.10%014%0.135CC..G310 helixtrans-64.9-23175.7-61.9-173.9-6900113.1A74 A84 G88 R89 Y90 S398 L402 F403 P404 D421A74-M400 HydrophobicContact CB-CE 4.21Å; A74-M400 HydrophobicContact CB-CG 3.77Å; A74-M400 HydrophobicContact CB-SD 3.81Å; A84-M400 HydrophobicContact CB-CG 3.99Å; A84-M400 HydrophobicContact CB-SD 4.3Å; G88-M400 WeakPolarHBondContact CA-O 3.24Å; R89-M400 VanDerWaalsContact C-SD 3.59Å; Y90-M400 HydrophobicContact CD1-CE 3.95Å; Y90-M400 HydrophobicContact CD1-SD 4.06Å; Y90-M400 HydrophobicContact CE1-CE 3.47Å; Y90-M400 VanDerWaalsContact CE1-CE 3.47Å; Y90-M400 HydrophobicContact CE1-SD 4.22Å; Y90-M400 HydrophobicContact CE2-CE 4.1Å; Y90-M400 HydrophobicContact CG-CE 4.43Å; Y90-M400 HydrophobicContact CG-SD 4.27Å; S398-M400 PolarHBondContact O-N 2.99Å; S398-M400 VanDerWaalsContact O-N 3.1Å; S398-M400 PolarHBondContact OG-N 3.34Å; M400-L402 PolarHBondContact O-N 3.3Å; M400-F403 WeakPolarHBondContact O-CB 3.46Å; M400-F403 PolarHBondContact O-N 2.85Å; M400-P404 VanDerWaalsContact O-CD 3.23Å; M400-P404 WeakPolarHBondContact O-CD 3.4Å; M400-D421 HydrophobicContact CE-CB 4.01Å; M400-D421 HydrophobicContact SD-CB 3.97Å
401D98.9Very high98.2Very high0 Ų025.4 Ų25.40%014%0.138CC..G310 helixtrans-70.8-20.8-175.5-63.9-17.1000112.8S398 N399 F403 P404 T405 G422 H423 L425 H438S398-D401 PolarHBondContact N-OD2 3.31Å; S398-D401 WeakPolarHBondContact O-CB 3.36Å; S398-D401 VanDerWaalsContact O-CG 3.3Å; S398-D401 PolarHBondContact O-N 2.76Å; N399-D401 PolarHBondContact O-N 3.39Å; D401-F403 PolarHBondContact O-N 3.43Å; D401-P404 WeakPolarHBondContact O-CD 3.41Å; D401-P404 VanDerWaalsContact O-CG 3.28Å; D401-P404 WeakPolarHBondContact O-CG 3.47Å; D401-T405 WeakPolarHBondContact O-CB 3.16Å; D401-T405 PolarHBondContact O-N 2.9Å; D401-T405 PolarHBondContact O-OG1 3.27Å; D401-G422 VanDerWaalsContact OD1-CA 3.25Å; D401-G422 WeakPolarHBondContact OD1-CA 3.11Å; D401-H423 WeakPolarHBondContact CA-O 3.45Å; D401-H423 WeakPolarHBondContact CB-O 3.36Å; D401-H423 PolarHBondContact OD1-N 2.8Å; D401-L425 HydrophobicContact CB-CD1 3.76Å; D401-L425 HydrophobicContact CB-CD2 3.76Å; D401-L425 HydrophobicContact CB-CG 3.64Å; D401-H438 IonicContact OD1-CD2 3.83Å; D401-H438 IonicContact OD1-CE1 3.97Å; D401-H438 PolarHBondContact OD1-CE1 3.29Å; D401-H438 IonicContact OD1-NE2 3.57Å; D401-H438 PolarHBondContact OD1-NE2 3.29Å; D401-H438 IonicContact OD2-CD2 2.92Å; D401-H438 PolarHBondContact OD2-CD2 3.5Å; D401-H438 IonicContact OD2-NE2 2.75Å; D401-H438 PolarHBondContact OD2-NE2 2.69Å
402L98.7Very high98.2Very high0 Ų023 Ų230%013%0.133CC..Hα-helixtrans-64.3-31.7175.1-116.7-48.3000112.2L34 F85 Y337 L381 N399 M400 I406L34-L402 HydrophobicContact CD2-CD1 4.01Å; L34-L402 HydrophobicContact CD2-CG 4.44Å; F85-L402 HydrophobicContact CD2-CB 4.35Å; F85-L402 HydrophobicContact CE2-CB 3.74Å; F85-L402 HydrophobicContact CE2-CG 4.06Å; Y337-L402 HydrophobicContact CD1-CD2 3.64Å; Y337-L402 HydrophobicContact CD1-CG 3.76Å; Y337-L402 HydrophobicContact CD2-CD2 3.56Å; Y337-L402 HydrophobicContact CD2-CG 4.5Å; Y337-L402 HydrophobicContact CE1-CD2 3.6Å; Y337-L402 HydrophobicContact CE1-CG 3.9Å; Y337-L402 HydrophobicContact CE2-CD2 3.49Å; Y337-L402 VanDerWaalsContact CE2-CD2 3.49Å; Y337-L402 HydrophobicContact CG-CD2 3.58Å; Y337-L402 HydrophobicContact CG-CG 4.04Å; Y337-L402 VanDerWaalsContact CZ-CD2 3.48Å; L381-L402 HydrophobicContact CD2-CD2 4.48Å; N399-L402 PolarHBondContact O-N 2.85Å; M400-L402 PolarHBondContact O-N 3.3Å; L402-I406 HydrophobicContact CD1-CD1 3.77Å; L402-I406 HydrophobicContact CD1-CG1 3.84Å; L402-I406 HydrophobicContact CG-CD1 4.5Å; L402-I406 WeakPolarHBondContact O-CB 3.45Å; L402-I406 WeakPolarHBondContact O-CD1 3Å; L402-I406 VanDerWaalsContact O-CG1 3.25Å; L402-I406 WeakPolarHBondContact O-CG1 3.46Å; L402-I406 PolarHBondContact O-N 3.03Å
403F98.9Very high98.1Very high1 Ų121.8 Ų21.80%0.00414%0.142CC..Hα-helixtrans-58.1-61.9177.8176.2-85.7000112.1L86 T87 G88 V119 F121 I124 M400 D401 T405 I406 V407 P415 I420L86-F403 VanDerWaalsContact O-CD2 3.25Å; L86-F403 WeakPolarHBondContact O-CD2 3.44Å; T87-F403 VanDerWaalsContact C-CD2 3.45Å; G88-F403 VanDerWaalsContact CA-CB 3.49Å; V119-F403 WeakPolarHBondContact O-CE2 3.37Å; F121-F403 HydrophobicContact CB-CD2 3.8Å; F121-F403 HydrophobicContact CB-CE2 4.31Å; F121-F403 HydrophobicContact CD1-CD2 4.33Å; I124-F403 HydrophobicContact CD1-CE1 4.4Å; I124-F403 HydrophobicContact CD1-CE2 4Å; I124-F403 HydrophobicContact CD1-CZ 3.56Å; M400-F403 WeakPolarHBondContact O-CB 3.46Å; M400-F403 PolarHBondContact O-N 2.85Å; D401-F403 PolarHBondContact O-N 3.43Å; F403-T405 VanDerWaalsContact C-N 3.31Å; F403-T405 PolarHBondContact O-N 3.33Å; F403-I406 PolarHBondContact O-N 3.05Å; F403-V407 HydrophobicContact CD1-CG2 4.33Å; F403-V407 HydrophobicContact CE1-CG2 4.06Å; F403-V407 HydrophobicContact CZ-CG2 4.21Å; F403-V407 VanDerWaalsContact O-CG2 3.26Å; F403-V407 WeakPolarHBondContact O-CG2 3.46Å; F403-V407 PolarHBondContact O-N 3.24Å; F403-P415 HydrophobicContact CZ-CG 4.22Å; F403-I420 HydrophobicContact CD1-CD1 4.4Å; F403-I420 HydrophobicContact CD1-CG2 3.94Å; F403-I420 HydrophobicContact CE1-CD1 3.75Å; F403-I420 HydrophobicContact CE1-CG1 4.24Å; F403-I420 HydrophobicContact CE1-CG2 4.2Å; F403-I420 HydrophobicContact CZ-CD1 4.23Å
404P98.8Very high98Very high8 Ų823.9 Ų23.95%0.05215%0.153CC..Hα-helixtrans-64.8-33.6-178.927.9-37.9000113M400 D401 V407 H408 I414 H423M400-P404 VanDerWaalsContact O-CD 3.23Å; M400-P404 WeakPolarHBondContact O-CD 3.4Å; D401-P404 WeakPolarHBondContact O-CD 3.41Å; D401-P404 VanDerWaalsContact O-CG 3.28Å; D401-P404 WeakPolarHBondContact O-CG 3.47Å; P404-V407 PolarHBondContact O-N 3.45Å; P404-H408 WeakPolarHBondContact O-CB 3.28Å; P404-H408 PolarHBondContact O-N 3.48Å; P404-I414 VanDerWaalsContact CA-CD1 3.5Å; P404-I414 HydrophobicContact CB-CD1 3.59Å; P404-H423 WeakPolarHBondContact CG-O 3.5Å
405T98.8Very high98Very high0 Ų019.6 Ų19.60%013%0.131CC..Hα-helixtrans-61.7-47.3175.4-70.40000112.3L335 D401 F403 H408 L409 D424 L425 M426L335-T405 HydrophobicContact CD2-CG2 4.44Å; D401-T405 WeakPolarHBondContact O-CB 3.16Å; D401-T405 PolarHBondContact O-N 2.9Å; D401-T405 PolarHBondContact O-OG1 3.27Å; F403-T405 VanDerWaalsContact C-N 3.31Å; F403-T405 PolarHBondContact O-N 3.33Å; T405-H408 PolarHBondContact O-N 3.01Å; T405-L409 HydrophobicContact CG2-CD1 3.79Å; T405-L409 HydrophobicContact CG2-CG 4.45Å; T405-L409 WeakPolarHBondContact O-CB 2.99Å; T405-L409 VanDerWaalsContact O-CG 3.24Å; T405-L409 WeakPolarHBondContact O-CG 3.34Å; T405-L409 PolarHBondContact O-N 3.33Å; T405-D424 VanDerWaalsContact CA-OD1 3.3Å; T405-D424 WeakPolarHBondContact CA-OD1 3.48Å; T405-D424 WeakPolarHBondContact CB-OD1 3.42Å; T405-D424 WeakPolarHBondContact OG1-CA 3.24Å; T405-D424 PolarHBondContact OG1-OD1 3.49Å; T405-L425 PolarHBondContact OG1-N 2.84Å; T405-M426 HydrophobicContact CG2-CG 4.03Å; T405-M426 HydrophobicContact CG2-SD 4.14Å
406I98.7Very high97.9Very high0 Ų026.7 Ų26.70%016%0.164CC..Hα-helixtrans-63.8-44176.6-71.5164.2000111F32 L34 F121 V125 L280 L402 F403 H408 L409 S410F32-I406 HydrophobicContact CD1-CG1 4.17Å; F32-I406 HydrophobicContact CD2-CG2 4.09Å; F32-I406 HydrophobicContact CE1-CG1 4.33Å; F32-I406 HydrophobicContact CE2-CG2 3.89Å; F32-I406 HydrophobicContact CG-CG1 4.44Å; F32-I406 HydrophobicContact CG-CG2 4.47Å; F32-I406 HydrophobicContact CZ-CG2 4.13Å; L34-I406 HydrophobicContact CD1-CD1 3.56Å; L34-I406 HydrophobicContact CD2-CD1 3.95Å; L34-I406 HydrophobicContact CG-CD1 4.35Å; F121-I406 HydrophobicContact CB-CB 4.34Å; F121-I406 HydrophobicContact CB-CD1 4.41Å; F121-I406 HydrophobicContact CB-CG2 4.1Å; F121-I406 HydrophobicContact CD1-CD1 4.17Å; F121-I406 HydrophobicContact CD2-CD1 3.94Å; F121-I406 HydrophobicContact CE1-CD1 4.42Å; F121-I406 HydrophobicContact CE2-CD1 4.28Å; F121-I406 HydrophobicContact CG-CD1 3.93Å; F121-I406 HydrophobicContact CZ-CD1 4.49Å; V125-I406 HydrophobicContact CG1-CG2 3.4Å; V125-I406 VanDerWaalsContact CG1-CG2 3.4Å; L280-I406 HydrophobicContact CD1-CD1 4.5Å; L280-I406 HydrophobicContact CD1-CG2 4.22Å; L402-I406 HydrophobicContact CD1-CD1 3.77Å; L402-I406 HydrophobicContact CD1-CG1 3.84Å; L402-I406 HydrophobicContact CG-CD1 4.5Å; L402-I406 WeakPolarHBondContact O-CB 3.45Å; L402-I406 WeakPolarHBondContact O-CD1 3Å; L402-I406 VanDerWaalsContact O-CG1 3.25Å; L402-I406 WeakPolarHBondContact O-CG1 3.46Å; L402-I406 PolarHBondContact O-N 3.03Å; F403-I406 PolarHBondContact O-N 3.05Å; I406-H408 VanDerWaalsContact C-N 3.35Å; I406-H408 PolarHBondContact O-N 3.4Å; I406-L409 PolarHBondContact O-N 2.96Å; I406-S410 WeakPolarHBondContact O-CB 3.32Å; I406-S410 PolarHBondContact O-N 3.25Å; I406-S410 PolarHBondContact O-OG 3.06Å
407V98.5Very high97.8Very high0 Ų032.2 Ų32.20%019%0.193CC..Hα-helixtrans-58.2-49.5179.31730000110.2I124 F403 P404 S410 G411 A412 I414I124-V407 HydrophobicContact CB-CG2 4.36Å; I124-V407 HydrophobicContact CD1-CG2 3.54Å; I124-V407 HydrophobicContact CG2-CG1 4.24Å; I124-V407 HydrophobicContact CG2-CG2 4.1Å; F403-V407 HydrophobicContact CD1-CG2 4.33Å; F403-V407 HydrophobicContact CE1-CG2 4.06Å; F403-V407 HydrophobicContact CZ-CG2 4.21Å; F403-V407 VanDerWaalsContact O-CG2 3.26Å; F403-V407 WeakPolarHBondContact O-CG2 3.46Å; F403-V407 PolarHBondContact O-N 3.24Å; P404-V407 PolarHBondContact O-N 3.45Å; V407-S410 PolarHBondContact O-N 3.42Å; V407-S410 PolarHBondContact O-OG 3.28Å; V407-G411 PolarHBondContact O-N 3.29Å; V407-A412 HydrophobicContact CG1-CB 3.84Å; V407-A412 PolarHBondContact O-N 3.16Å; V407-A412 VanDerWaalsContact O-N 3.09Å; V407-I414 HydrophobicContact CB-CD1 3.75Å; V407-I414 HydrophobicContact CG1-CD1 3.67Å; V407-I414 HydrophobicContact CG1-CG1 4.22Å; V407-I414 HydrophobicContact CG2-CD1 4.3Å
408H97.6Very high97.7Very high107 Ų10734.7 Ų34.750%0.49520%0.203SC..Hα-helixtrans-58.1-53.3176.9174.9-163.1000111.4P404 T405 I406 S410 G411 D424P404-H408 WeakPolarHBondContact O-CB 3.28Å; P404-H408 PolarHBondContact O-N 3.48Å; T405-H408 PolarHBondContact O-N 3.01Å; I406-H408 VanDerWaalsContact C-N 3.35Å; I406-H408 PolarHBondContact O-N 3.4Å; H408-S410 PolarHBondContact O-N 3.05Å; H408-G411 PolarHBondContact O-N 3.06Å; H408-D424 IonicContact CE1-OD2 3.87Å; H408-D424 IonicContact CG-OD2 3.9Å; H408-D424 IonicContact ND1-OD2 2.95Å; H408-D424 PolarHBondContact ND1-OD2 2.87Å
409L97.9Very high97.6Very high32 Ų3239.9 Ų39.917%0.16823%0.227CC..Hα-helixtrans-64.3-26.1-177.2-70.1174.9000113.7P30 F32 L335 W383 T405 I406 G411 M426P30-L409 WeakPolarHBondContact CD-O 3.24Å; P30-L409 HydrophobicContact CG-CB 4.18Å; F32-L409 HydrophobicContact CE1-CB 3.8Å; F32-L409 HydrophobicContact CE1-CD1 3.93Å; F32-L409 HydrophobicContact CZ-CB 3.7Å; L335-L409 HydrophobicContact CD2-CD1 3.64Å; W383-L409 HydrophobicContact CE3-CD1 4.43Å; W383-L409 HydrophobicContact CH2-CD1 4.45Å; W383-L409 HydrophobicContact CH2-CD2 3.96Å; W383-L409 HydrophobicContact CZ3-CD1 3.64Å; W383-L409 HydrophobicContact CZ3-CD2 3.63Å; W383-L409 HydrophobicContact CZ3-CG 4.23Å; T405-L409 HydrophobicContact CG2-CD1 3.79Å; T405-L409 HydrophobicContact CG2-CG 4.45Å; T405-L409 WeakPolarHBondContact O-CB 2.99Å; T405-L409 VanDerWaalsContact O-CG 3.24Å; T405-L409 WeakPolarHBondContact O-CG 3.34Å; T405-L409 PolarHBondContact O-N 3.33Å; I406-L409 PolarHBondContact O-N 2.96Å; L409-G411 PolarHBondContact O-N 3.13Å; L409-M426 HydrophobicContact CD1-CG 4.22Å; L409-M426 HydrophobicContact CD1-SD 3.84Å; L409-M426 HydrophobicContact CD2-CE 4.33Å; L409-M426 HydrophobicContact CD2-CG 3.95Å; L409-M426 HydrophobicContact CD2-SD 4.12Å; L409-M426 HydrophobicContact CG-CG 4.15Å; L409-M426 HydrophobicContact CG-SD 4.34Å
410S97.4Very high97.6Very high1 Ų141.4 Ų41.41%0.00724%0.235CC..THydrogen-bonded Turntrans-76.6-9.4174.574.90000114K29 I406 V407 H408 A412K29-S410 WeakPolarHBondContact CE-O 3.37Å; I406-S410 WeakPolarHBondContact O-CB 3.32Å; I406-S410 PolarHBondContact O-N 3.25Å; I406-S410 PolarHBondContact O-OG 3.06Å; V407-S410 PolarHBondContact O-N 3.42Å; V407-S410 PolarHBondContact O-OG 3.28Å; H408-S410 PolarHBondContact O-N 3.05Å; S410-A412 VanDerWaalsContact C-N 3.34Å; S410-A412 WeakPolarHBondContact OG-CB 3.48Å; S410-A412 PolarHBondContact OG-N 2.78Å
411G96.3Very high97.6Very high63 Ų6342.3 Ų42.365%0.64924%0.24SC*.THydrogen-bonded Turntrans79.212.8-173.200000114.2V407 H408 L409V407-G411 PolarHBondContact O-N 3.29Å; H408-G411 PolarHBondContact O-N 3.06Å; L409-G411 PolarHBondContact O-N 3.13Å
412A96.6Very high97.6Very high20 Ų2042.6 Ų42.617%0.16524%0.242CC..PPolyproline II helixtrans-86.7164.7176.200000112I124 Q128 V407 S410I124-A412 HydrophobicContact CG2-CB 3.31Å; Q128-A412 HydrophobicContact CG-CB 3.83Å; V407-A412 HydrophobicContact CG1-CB 3.84Å; V407-A412 PolarHBondContact O-N 3.16Å; V407-A412 VanDerWaalsContact O-N 3.09Å; S410-A412 VanDerWaalsContact C-N 3.34Å; S410-A412 WeakPolarHBondContact OG-CB 3.48Å; S410-A412 PolarHBondContact OG-N 2.78Å
413A96.1Very high97.5Very high84 Ų8445.7 Ų45.769%0.69426%0.257SS*.PPolyproline II helixtrans-95.4143.2172.400000111
414I96.8Very high97.5Very high50 Ų5047.7 Ų47.726%0.25627%0.268SS..PPolyproline II helixtrans-63.7136.3172.6-60.5-72.3000109.4P404 V407 Q416 I420P404-I414 VanDerWaalsContact CA-CD1 3.5Å; P404-I414 HydrophobicContact CB-CD1 3.59Å; V407-I414 HydrophobicContact CB-CD1 3.75Å; V407-I414 HydrophobicContact CG1-CD1 3.67Å; V407-I414 HydrophobicContact CG1-CG1 4.22Å; V407-I414 HydrophobicContact CG2-CD1 4.3Å; I414-Q416 PolarHBondContact O-N 3.47Å; I414-Q416 PolarHBondContact O-NE2 3.37Å; I414-I420 HydrophobicContact CG2-CB 4.33Å; I414-I420 HydrophobicContact CG2-CG1 3.75Å
415P96Very high97.5Very high23 Ų2347.6 Ų47.615%0.14927%0.266CS..PPolyproline II helixtrans-54.9129174.8-2635.1000112.1V119 I124 F403 R418V119-P415 HydrophobicContact CG1-CG 4.31Å; I124-P415 HydrophobicContact CD1-CG 4.02Å; F403-P415 HydrophobicContact CZ-CG 4.22Å; P415-R418 HydrophobicContact CB-CG 4.12Å
416Q96.6Very high97.5Very high170 Ų17047.9 Ų47.979%0.79427%0.268SS*.SBendtrans-99.6-7.5-178.7-58.6-60.2-58.100113I414 R418I414-Q416 PolarHBondContact O-N 3.47Å; I414-Q416 PolarHBondContact O-NE2 3.37Å; Q416-R418 VanDerWaalsContact C-N 3.28Å
417D96.3Very high97.4Very high116 Ų11651.3 Ų51.362%0.6229%0.286SS*.SBendtrans-83.6-4.4-178.569.4-33.1000113.1
418R96.3Very high97.4Very high52 Ų5251.7 Ų51.720%0.19629%0.288CS..SBendtrans-153.6150.3-171.775.2-169.965.7-158.2-1.8110.8R117 E118 P415 Q416 I420R117-R418 PolarHBondContact O-NH1 3.29Å; R117-R418 PolarHBondContact O-NH2 3.42Å; E118-R418 IonicContact OE2-NH1 3.3Å; P415-R418 HydrophobicContact CB-CG 4.12Å; Q416-R418 VanDerWaalsContact C-N 3.28Å; R418-I420 HydrophobicContact CG-CD1 4.08Å
419E96.9Very high97.5Very high111 Ų11146.6 Ų46.652%0.51927%0.265SS..  trans-64137.9172.3-60.1-61.6162.800111R89R89-E419 VanDerWaalsContact CG-O 3.25Å; R89-E419 WeakPolarHBondContact CG-O 3.48Å; R89-E419 PolarHBondContact NH1-O 3.4Å
420I98.3Very high97.5Very high31 Ų3146.9 Ų46.916%0.15927%0.265CS..  trans-117.3122.4169.3-59.8-61.4000106.2R89 F403 I414 R418R89-I420 HydrophobicContact CG-CD1 3.98Å; F403-I420 HydrophobicContact CD1-CD1 4.4Å; F403-I420 HydrophobicContact CD1-CG2 3.94Å; F403-I420 HydrophobicContact CE1-CD1 3.75Å; F403-I420 HydrophobicContact CE1-CG1 4.24Å; F403-I420 HydrophobicContact CE1-CG2 4.2Å; F403-I420 HydrophobicContact CZ-CD1 4.23Å; I414-I420 HydrophobicContact CG2-CB 4.33Å; I414-I420 HydrophobicContact CG2-CG1 3.75Å; R418-I420 HydrophobicContact CG-CD1 4.08Å
421D98.6Very high97.4Very high20 Ų2048.9 Ų48.911%0.10729%0.286CS..  trans-89.9-22.2-174.8-57.3-74.6000112G88 R89 Y90 R93 M400G88-D421 PolarHBondContact O-N 3.47Å; R89-D421 VanDerWaalsContact CA-OD2 3.28Å; R89-D421 WeakPolarHBondContact CA-OD2 3.08Å; Y90-D421 HydrophobicContact CD2-CB 3.78Å; Y90-D421 VanDerWaalsContact CD2-OD1 3.28Å; Y90-D421 WeakPolarHBondContact CD2-OD1 3.29Å; Y90-D421 WeakPolarHBondContact CD2-OD2 3.35Å; Y90-D421 HydrophobicContact CE2-CB 3.73Å; Y90-D421 PolarHBondContact N-OD2 2.9Å; R93-D421 WeakPolarHBondContact CD-OD2 3.2Å; R93-D421 IonicContact CZ-OD1 3.65Å; R93-D421 VanDerWaalsContact CZ-OD1 3.27Å; R93-D421 IonicContact CZ-OD2 2.74Å; R93-D421 VanDerWaalsContact NE-CG 3.29Å; R93-D421 IonicContact NE-OD1 3.2Å; R93-D421 PolarHBondContact NE-OD1 2.93Å; R93-D421 IonicContact NE-OD2 2.85Å; R93-D421 PolarHBondContact NE-OD2 3.03Å; R93-D421 IonicContact NH2-OD1 4Å; R93-D421 PolarHBondContact NH2-OD1 2.91Å; M400-D421 HydrophobicContact CE-CB 4.01Å; M400-D421 HydrophobicContact SD-CB 3.97Å
422G98.6Very high97.5Very high5 Ų553.8 Ų53.85%0.05229%0.285CS..  trans-72.2154.8171.600000112.4G88 D401G88-G422 PolarHBondContact O-N 3.07Å; D401-G422 VanDerWaalsContact OD1-CA 3.25Å; D401-G422 WeakPolarHBondContact OD1-CA 3.11Å
423H98.5Very high97.5Very high65 Ų6554.3 Ų54.330%0.30129%0.289SS..  trans-120.8147.3174.4-64.9-59.5000112.2D401 P404 L425 N437 H438D401-H423 WeakPolarHBondContact CA-O 3.45Å; D401-H423 WeakPolarHBondContact CB-O 3.36Å; D401-H423 PolarHBondContact OD1-N 2.8Å; P404-H423 WeakPolarHBondContact CG-O 3.5Å; H423-L425 PolarHBondContact O-N 3.31Å; H423-N437 HydrophobicContact CB-CB 3.88Å; H423-H438 AromaticContact CD2-CE1 3.33Å; H423-H438 PolarHBondContact CD2-CE1 3.02Å; H423-H438 AromaticContact CD2-CG 3.93Å; H423-H438 AromaticContact CD2-ND1 3.51Å; H423-H438 AromaticContact CD2-NE2 3.69Å; H423-H438 AromaticContact NE2-ND1 4Å
424D98.5Very high97.4Very high44 Ų4458.8 Ų58.824%0.23530%0.296CS..  trans-64.9127.6174.5178.928.2000111T405 H408 M426T405-D424 VanDerWaalsContact CA-OD1 3.3Å; T405-D424 WeakPolarHBondContact CA-OD1 3.48Å; T405-D424 WeakPolarHBondContact CB-OD1 3.42Å; T405-D424 WeakPolarHBondContact OG1-CA 3.24Å; T405-D424 PolarHBondContact OG1-OD1 3.49Å; H408-D424 IonicContact CE1-OD2 3.87Å; H408-D424 IonicContact CG-OD2 3.9Å; H408-D424 IonicContact ND1-OD2 2.95Å; H408-D424 PolarHBondContact ND1-OD2 2.87Å; D424-M426 PolarHBondContact OD1-N 2.57Å; D424-M426 VanDerWaalsContact OD1-N 3.09Å
425L98.5Very high97.4Very high5 Ų560.9 Ų60.93%0.02630%0.3CS..  trans-88.5-11.4-179.7-59.3179.2000113.9T397 D401 T405 H423 D427 L428 L429T397-L425 HydrophobicContact CG2-CD2 3.7Å; D401-L425 HydrophobicContact CB-CD1 3.76Å; D401-L425 HydrophobicContact CB-CD2 3.76Å; D401-L425 HydrophobicContact CB-CG 3.64Å; T405-L425 PolarHBondContact OG1-N 2.84Å; H423-L425 PolarHBondContact O-N 3.31Å; L425-D427 PolarHBondContact O-N 2.8Å; L425-L428 HydrophobicContact CD2-CD2 4.38Å; L425-L428 CarbonylContact O-C 3.6Å; L425-L428 WeakPolarHBondContact O-CA 3.44Å; L425-L428 WeakPolarHBondContact O-CB 3.41Å; L425-L428 PolarHBondContact O-N 3.3Å; L425-L429 HydrophobicContact CB-CD1 3.7Å; L425-L429 HydrophobicContact CB-CG 3.92Å; L425-L429 VanDerWaalsContact O-CG 3.25Å; L425-L429 WeakPolarHBondContact O-CG 3.33Å; L425-L429 PolarHBondContact O-N 3.18Å
426M98.1Very high97.5Very high6 Ų660.5 Ų60.53%0.0330%0.299CS..Hα-helixtrans-58.2-44.9-167.1-75.9-55-56.800114W383 T405 L409 D424 L428 L429 Q430W383-M426 HydrophobicContact CE3-CE 4.37Å; W383-M426 HydrophobicContact CZ3-CE 4.22Å; T405-M426 HydrophobicContact CG2-CG 4.03Å; T405-M426 HydrophobicContact CG2-SD 4.14Å; L409-M426 HydrophobicContact CD1-CG 4.22Å; L409-M426 HydrophobicContact CD1-SD 3.84Å; L409-M426 HydrophobicContact CD2-CE 4.33Å; L409-M426 HydrophobicContact CD2-CG 3.95Å; L409-M426 HydrophobicContact CD2-SD 4.12Å; L409-M426 HydrophobicContact CG-CG 4.15Å; L409-M426 HydrophobicContact CG-SD 4.34Å; D424-M426 PolarHBondContact OD1-N 2.57Å; D424-M426 VanDerWaalsContact OD1-N 3.09Å; M426-L428 VanDerWaalsContact C-N 3.29Å; M426-L428 PolarHBondContact O-N 3.46Å; M426-L429 PolarHBondContact O-N 3.05Å; M426-L429 HydrophobicContact SD-CD1 4.09Å; M426-Q430 HydrophobicContact CE-CG 3.95Å; M426-Q430 VanDerWaalsContact O-CB 3.25Å; M426-Q430 WeakPolarHBondContact O-CB 3.46Å; M426-Q430 WeakPolarHBondContact O-CG 3.4Å; M426-Q430 PolarHBondContact O-N 2.97Å; M426-Q430 PolarHBondContact O-OE1 2.79Å
427D98.1Very high97.5Very high73 Ų7357.9 Ų57.939%0.3929%0.29SS..Hα-helixtrans-64.3-36177.7-76-22.2000112.1L425 G431 R432 A433L425-D427 PolarHBondContact O-N 2.8Å; D427-G431 PolarHBondContact O-N 2.9Å; D427-G431 VanDerWaalsContact O-N 3.11Å; D427-R432 HydrophobicContact CB-CB 4.16Å; D427-R432 PolarHBondContact O-N 3.47Å; D427-R432 WeakPolarHBondContact OD1-CD 3.49Å; D427-R432 IonicContact OD1-CZ 2.69Å; D427-R432 IonicContact OD1-NE 2.86Å; D427-R432 IonicContact OD1-NH1 3.74Å; D427-R432 PolarHBondContact OD1-NH1 3.28Å; D427-A433 HydrophobicContact CB-CB 4.04Å; D427-A433 PolarHBondContact O-N 3.46Å
428L98.4Very high97.5Very high7 Ų752.6 Ų52.64%0.03726%0.261CS..Hα-helixtrans-66.2-49.5174.9-178.162.9000110.8R391 I393 E395 T397 L425 M426 Q430 G431R391-L428 PolarHBondContact NH1-O 2.94Å; R391-L428 PolarHBondContact NH2-O 2.74Å; I393-L428 HydrophobicContact CD1-CD1 4.46Å; I393-L428 HydrophobicContact CD1-CG 4.01Å; I393-L428 HydrophobicContact CG2-CD1 4.08Å; I393-L428 HydrophobicContact CG2-CD2 4.04Å; I393-L428 HydrophobicContact CG2-CG 4.08Å; E395-L428 HydrophobicContact CB-CD1 4.44Å; E395-L428 HydrophobicContact CB-CD2 4.24Å; E395-L428 HydrophobicContact CG-CD1 4.24Å; T397-L428 HydrophobicContact CG2-CD2 3.8Å; L425-L428 HydrophobicContact CD2-CD2 4.38Å; L425-L428 CarbonylContact O-C 3.6Å; L425-L428 WeakPolarHBondContact O-CA 3.44Å; L425-L428 WeakPolarHBondContact O-CB 3.41Å; L425-L428 PolarHBondContact O-N 3.3Å; M426-L428 VanDerWaalsContact C-N 3.29Å; M426-L428 PolarHBondContact O-N 3.46Å; L428-Q430 VanDerWaalsContact C-N 3.32Å; L428-Q430 PolarHBondContact O-N 2.84Å; L428-G431 PolarHBondContact O-N 2.81Å
429L98.3Very high97.6Very high1 Ų153.8 Ų53.81%0.00527%0.269CS..Hα-helixtrans-61.1-40.3179.7-64.6166.7000111.9V66 L68 L381 I387 P388 R391 I393 L425 M426 G431V66-L429 HydrophobicContact CB-CD2 4.04Å; V66-L429 HydrophobicContact CG1-CD2 3.84Å; V66-L429 HydrophobicContact CG2-CD2 4.28Å; L68-L429 HydrophobicContact CD2-CD2 4.38Å; L381-L429 HydrophobicContact CB-CD2 4.23Å; L381-L429 HydrophobicContact CD1-CD2 4.34Å; L381-L429 HydrophobicContact CD2-CD1 3.6Å; L381-L429 HydrophobicContact CD2-CD2 4.16Å; L381-L429 HydrophobicContact CG-CD2 4.48Å; I387-L429 HydrophobicContact CD1-CB 4.33Å; I387-L429 HydrophobicContact CD1-CD1 4.11Å; I387-L429 HydrophobicContact CG1-CB 4.32Å; P388-L429 WeakPolarHBondContact CD-O 3.39Å; R391-L429 PolarHBondContact NH1-O 3.35Å; I393-L429 HydrophobicContact CD1-CD2 4.46Å; L425-L429 HydrophobicContact CB-CD1 3.7Å; L425-L429 HydrophobicContact CB-CG 3.92Å; L425-L429 VanDerWaalsContact O-CG 3.25Å; L425-L429 WeakPolarHBondContact O-CG 3.33Å; L425-L429 PolarHBondContact O-N 3.18Å; M426-L429 PolarHBondContact O-N 3.05Å; M426-L429 HydrophobicContact SD-CD1 4.09Å; L429-G431 VanDerWaalsContact C-N 3.29Å; L429-G431 PolarHBondContact O-N 2.95Å
430Q97.9Very high97.7Very high38 Ų3850.7 Ų50.718%0.17825%0.254CS..Hα-helixtrans-80.8-9-179.2-66.7-179.4-52.800113.6Q386 M426 L428 R432Q386-Q430 WeakPolarHBondContact O-CG 3.48Å; Q386-Q430 PolarHBondContact O-NE2 2.79Å; Q386-Q430 VanDerWaalsContact O-NE2 3.08Å; M426-Q430 HydrophobicContact CE-CG 3.95Å; M426-Q430 VanDerWaalsContact O-CB 3.25Å; M426-Q430 WeakPolarHBondContact O-CB 3.46Å; M426-Q430 WeakPolarHBondContact O-CG 3.4Å; M426-Q430 PolarHBondContact O-N 2.97Å; M426-Q430 PolarHBondContact O-OE1 2.79Å; L428-Q430 VanDerWaalsContact C-N 3.32Å; L428-Q430 PolarHBondContact O-N 2.84Å; Q430-R432 VanDerWaalsContact C-N 3.32Å; Q430-R432 HydrophobicContact CB-CG 4.14Å; Q430-R432 VanDerWaalsContact CD-NH2 3.33Å
431G96.4Very high97.7Very high43 Ų4349.4 Ų49.444%0.44325%0.247SC..THydrogen-bonded Turntrans78.119.4178.200000113.4D427 L428 L429D427-G431 PolarHBondContact O-N 2.9Å; D427-G431 VanDerWaalsContact O-N 3.11Å; L428-G431 PolarHBondContact O-N 2.81Å; L429-G431 VanDerWaalsContact C-N 3.29Å; L429-G431 PolarHBondContact O-N 2.95Å
432R97.5Very high97.7Very high165 Ų16549.3 Ų49.362%0.62325%0.246SC*.SBendtrans-82.7-25171.8-52.8-172.6-154.2147.8-8.1111.7D427 Q430D427-R432 HydrophobicContact CB-CB 4.16Å; D427-R432 PolarHBondContact O-N 3.47Å; D427-R432 WeakPolarHBondContact OD1-CD 3.49Å; D427-R432 IonicContact OD1-CZ 2.69Å; D427-R432 IonicContact OD1-NE 2.86Å; D427-R432 IonicContact OD1-NH1 3.74Å; D427-R432 PolarHBondContact OD1-NH1 3.28Å; Q430-R432 VanDerWaalsContact C-N 3.32Å; Q430-R432 HydrophobicContact CB-CG 4.14Å; Q430-R432 VanDerWaalsContact CD-NH2 3.33Å
433A96.9Very high97.7Very high31 Ų3149.2 Ų49.226%0.25625%0.245SC..  trans-115.8138.2168.500000109.9D427D427-A433 HydrophobicContact CB-CB 4.04Å; D427-A433 PolarHBondContact O-N 3.46Å
434E94.7Very high97.7Very high178 Ų17846.7 Ų46.783%0.83223%0.232SC*.SBendtrans-86.3-25.7173.7-65.9-175.1168.800112.2
435R96.3Very high97.6Very high94 Ų9445 Ų4536%0.35522%0.224SC..SBendtrans-116.9147.8-178.2-68.7-168.6-177.4-130.82.8112.6E395 H455 P456 P457 S459E395-R435 VanDerWaalsContact OE2-CA 3.32Å; E395-R435 WeakPolarHBondContact OE2-CA 3.47Å; R435-H455 PolarHBondContact NH1-CE1 2.54Å; R435-H455 VanDerWaalsContact NH1-CE1 3.35Å; R435-H455 PolarHBondContact NH1-NE2 3.13Å; R435-P456 PolarHBondContact NH1-O 2.95Å; R435-P457 PolarHBondContact NH1-O 2.95Å; R435-P457 VanDerWaalsContact NH1-O 3.16Å; R435-P457 PolarHBondContact NH2-O 2.97Å; R435-S459 PolarHBondContact NH1-O 2.87Å; R435-S459 PolarHBondContact NH2-O 3.49Å
436S96.9Very high97.4Very high16 Ų1645.4 Ų45.411%0.11223%0.226CC..  trans-69.6157.8164.9650000110.7E395 P396 H438E395-S436 PolarHBondContact OE2-N 3.33Å; E395-S436 PolarHBondContact OE2-OG 2.87Å; P396-S436 WeakPolarHBondContact O-CB 3.38Å; P396-S436 PolarHBondContact O-OG 2.78Å; S436-H438 PolarHBondContact O-N 2.72Å
437N96.8Very high97.2Very high114 Ų11446.2 Ų46.261%0.6123%0.232SC*.SBendtrans-78.31.6172.1-69.6-39.8000112.8H423 E439H423-N437 HydrophobicContact CB-CB 3.88Å; N437-E439 PolarHBondContact O-N 2.75Å; N437-E439 VanDerWaalsContact O-N 3.14Å
438H97.9Very high97.2Very high5 Ų545.4 Ų45.42%0.02322%0.224CC..  trans-85.477.1-179.8-76.7-60.5000112P396 D401 H423 S436 L441P396-H438 HydrophobicContact CB-CB 4.39Å; P396-H438 PolarHBondContact O-CD2 3.08Å; D401-H438 IonicContact OD1-CD2 3.83Å; D401-H438 IonicContact OD1-CE1 3.97Å; D401-H438 PolarHBondContact OD1-CE1 3.29Å; D401-H438 IonicContact OD1-NE2 3.57Å; D401-H438 PolarHBondContact OD1-NE2 3.29Å; D401-H438 IonicContact OD2-CD2 2.92Å; D401-H438 PolarHBondContact OD2-CD2 3.5Å; D401-H438 IonicContact OD2-NE2 2.75Å; D401-H438 PolarHBondContact OD2-NE2 2.69Å; H423-H438 AromaticContact CD2-CE1 3.33Å; H423-H438 PolarHBondContact CD2-CE1 3.02Å; H423-H438 AromaticContact CD2-CG 3.93Å; H423-H438 AromaticContact CD2-ND1 3.51Å; H423-H438 AromaticContact CD2-NE2 3.69Å; H423-H438 AromaticContact NE2-ND1 4Å; S436-H438 PolarHBondContact O-N 2.72Å; H438-L441 HydrophobicContact CB-CD1 4.11Å; H438-L441 HydrophobicContact CB-CG 4.1Å; H438-L441 WeakPolarHBondContact ND1-CD2 3.23Å
439E97.6Very high97.1Very high78 Ų7846.1 Ų46.136%0.36423%0.228SC..SBendtrans-66.2-43.5166.3-178.5176.8167.900110.6N437 W454 H455 P457N437-E439 PolarHBondContact O-N 2.75Å; N437-E439 VanDerWaalsContact O-N 3.14Å; E439-W454 CarbonylContact O-C 3.53Å; E439-W454 WeakPolarHBondContact O-CA 3.44Å; E439-W454 PolarHBondContact OE1-NE1 2.88Å; E439-H455 PolarHBondContact O-N 2.72Å; E439-P457 HydrophobicContact CG-CG 4.46Å
440F98.6Very high97.1Very high46 Ų4646.1 Ų46.120%0.20223%0.228CC..EExtended strand (participates in β ladder)trans-125.1133.4178.2-71.8-83.2000111.7F442 V452 R453 W454 M529 A532F440-F442 HydrophobicContact CB-CE2 4.12Å; F440-F442 HydrophobicContact CB-CZ 3.91Å; F440-V452 HydrophobicContact CD1-CG2 4.15Å; F440-R453 WeakPolarHBondContact CA-O 3.43Å; F440-W454 HydrophobicContact CD1-CB 3.82Å; F440-W454 AromaticContact CD1-CD1 3.6Å; F440-W454 AromaticContact CD1-CG 3.9Å; F440-W454 HydrophobicContact CD1-CG 3.9Å; F440-W454 AromaticContact CD2-CD1 3.97Å; F440-W454 HydrophobicContact CE1-CB 3.59Å; F440-W454 AromaticContact CE1-CD1 3.13Å; F440-W454 HydrophobicContact CE1-CD2 4.06Å; F440-W454 AromaticContact CE1-CG 3.32Å; F440-W454 HydrophobicContact CE1-CG 3.32Å; F440-W454 AromaticContact CE1-NE1 3.74Å; F440-W454 AromaticContact CE2-CD1 3.54Å; F440-W454 HydrophobicContact CE2-CG 4.48Å; F440-W454 AromaticContact CE2-NE1 3.57Å; F440-W454 HydrophobicContact CZ-CB 4.42Å; F440-W454 AromaticContact CZ-CD1 3.1Å; F440-W454 HydrophobicContact CZ-CD2 4.1Å; F440-W454 AromaticContact CZ-CE2 3.84Å; F440-W454 AromaticContact CZ-CG 3.67Å; F440-W454 HydrophobicContact CZ-CG 3.67Å; F440-W454 AromaticContact CZ-NE1 3.2Å; F440-M529 HydrophobicContact CE1-CG 4.34Å; F440-A532 HydrophobicContact CD1-CB 3.52Å; F440-A532 HydrophobicContact CD2-CB 3.87Å; F440-A532 HydrophobicContact CE1-CB 3.37Å; F440-A532 HydrophobicContact CE2-CB 3.74Å; F440-A532 HydrophobicContact CG-CB 3.76Å; F440-A532 HydrophobicContact CZ-CB 3.49Å; F440-A532 VanDerWaalsContact CZ-CB 3.49Å
441L98.8Very high97.2Very high3 Ų344.3 Ų44.32%0.01622%0.22CC..EExtended strand (participates in β ladder)trans-122.6136.3170.1-79.5164.5000109.4V72 P396 H438 R453V72-L441 HydrophobicContact CG2-CD1 4Å; P396-L441 HydrophobicContact CB-CD1 3.91Å; H438-L441 HydrophobicContact CB-CD1 4.11Å; H438-L441 HydrophobicContact CB-CG 4.1Å; H438-L441 WeakPolarHBondContact ND1-CD2 3.23Å; L441-R453 HydrophobicContact CB-CB 4.18Å; L441-R453 PolarHBondContact N-O 2.77Å; L441-R453 PolarHBondContact O-N 2.81Å
442F98.8Very high97.3Very high18 Ų1842.3 Ų42.38%0.07920%0.199CC..EExtended strand (participates in β ladder)trans-109.8124.6-176.2-56.9-80.6000109.6Y90 F440 Y444 L449 V452 A532 V533 H536Y90-F442 HydrophobicContact CE1-CB 4.33Å; Y90-F442 WeakPolarHBondContact CE1-O 3.43Å; Y90-F442 HydrophobicContact CE2-CB 4.37Å; Y90-F442 HydrophobicContact CE2-CD2 4.01Å; Y90-F442 PolarHBondContact OH-N 3.31Å; F440-F442 HydrophobicContact CB-CE2 4.12Å; F440-F442 HydrophobicContact CB-CZ 3.91Å; F442-Y444 HydrophobicContact CB-CD2 4.44Å; F442-Y444 HydrophobicContact CB-CE2 4.08Å; F442-L449 HydrophobicContact CB-CD1 3.98Å; F442-L449 HydrophobicContact CD1-CD1 4.44Å; F442-V452 HydrophobicContact CD1-CB 4.34Å; F442-V452 HydrophobicContact CD1-CG2 3.81Å; F442-V452 HydrophobicContact CE1-CG2 3.78Å; F442-A532 HydrophobicContact CZ-CB 4.38Å; F442-V533 HydrophobicContact CD1-CG2 4.05Å; F442-V533 HydrophobicContact CE1-CG2 3.83Å; F442-H536 HydrophobicContact CD1-CB 4.17Å; F442-H536 AromaticContact CD1-CD2 3.99Å; F442-H536 AromaticContact CD1-CG 3.99Å; F442-H536 HydrophobicContact CD2-CB 4.18Å; F442-H536 AromaticContact CD2-CE1 3.74Å; F442-H536 AromaticContact CD2-CG 3.6Å; F442-H536 AromaticContact CD2-ND1 3.41Å; F442-H536 WeakPolarHBondContact CD2-ND1 3.38Å; F442-H536 HydrophobicContact CE1-CB 3.66Å; F442-H536 AromaticContact CE1-CG 3.97Å; F442-H536 HydrophobicContact CE2-CB 3.67Å; F442-H536 AromaticContact CE2-CG 3.59Å; F442-H536 AromaticContact CE2-ND1 3.52Å; F442-H536 HydrophobicContact CG-CB 4.41Å; F442-H536 AromaticContact CG-CD2 3.81Å; F442-H536 AromaticContact CG-CG 3.81Å; F442-H536 HydrophobicContact CZ-CB 3.39Å; F442-H536 AromaticContact CZ-CG 3.78Å
443H98.7Very high97.3Very high4 Ų434.5 Ų34.52%0.01917%0.169CC..EExtended strand (participates in β ladder)trans-106.3107.2-175.4-55.1-62.8000109.6N370 I375 N450 A451 R453N370-H443 HydrophobicContact CB-CB 3.99Å; I375-H443 WeakPolarHBondContact CD1-ND1 3.34Å; H443-N450 WeakPolarHBondContact O-CB 3.28Å; H443-N450 PolarHBondContact O-N 2.82Å; H443-A451 WeakPolarHBondContact CA-O 3.44Å; H443-A451 HydrophobicContact CB-CB 4.09Å; H443-A451 PolarHBondContact N-O 3.09Å; H443-A451 PolarHBondContact O-N 3.33Å; H443-A451 VanDerWaalsContact O-N 3.07Å; H443-R453 VanDerWaalsContact NE2-CB 3.29Å; H443-R453 WeakPolarHBondContact NE2-CB 3.32Å
444Y98.2Very high97.4Very high11 Ų1134.8 Ų34.84%0.04316%0.164CC..EExtended strand (participates in β ladder)trans-91137178.2-80.4-93.2000111Y90 I92 N370 F442 N446 Y448 L449 H536Y90-Y444 HydrophobicContact CD1-CD2 4.32Å; I92-Y444 HydrophobicContact CB-CE1 4.28Å; I92-Y444 HydrophobicContact CG1-CE1 4.34Å; I92-Y444 HydrophobicContact CG2-CE1 4.18Å; I92-Y444 HydrophobicContact CG2-CE2 4.17Å; N370-Y444 PolarHBondContact ND2-O 2.88Å; N370-Y444 PolarHBondContact OD1-O 2.86Å; F442-Y444 HydrophobicContact CB-CD2 4.44Å; F442-Y444 HydrophobicContact CB-CE2 4.08Å; Y444-N446 WeakPolarHBondContact CB-O 3.28Å; Y444-Y448 CarbonylContact C-O 3.53Å; Y444-Y448 WeakPolarHBondContact CA-O 3.48Å; Y444-L449 HydrophobicContact CD1-CB 4.29Å; Y444-L449 HydrophobicContact CD2-CD1 4.12Å; Y444-L449 HydrophobicContact CE1-CB 3.87Å; Y444-L449 HydrophobicContact CE1-CD1 4.33Å; Y444-L449 HydrophobicContact CE2-CD1 3.82Å; Y444-L449 HydrophobicContact CG-CD1 4.5Å; Y444-H536 AromaticContact CE2-NE2 3.46Å; Y444-H536 WeakPolarHBondContact CE2-NE2 3.07Å; Y444-H536 AromaticContact CZ-NE2 3.68Å; Y444-H536 PolarHBondContact OH-CD2 2.67Å; Y444-H536 PolarHBondContact OH-NE2 3.2Å
445C96.6Very high97.6Very high8 Ų826.7 Ų26.75%0.05413%0.126CC..EExtended strand (participates in β ladder)trans-102.798.9164.4-163.30000106.6N370 S447 Y448 N450 F468 C488N370-C445 PolarHBondContact ND2-N 3.14Å; C445-S447 PolarHBondContact O-N 3.13Å; C445-Y448 PolarHBondContact N-O 3.31Å; C445-Y448 WeakPolarHBondContact O-CB 3.17Å; C445-Y448 WeakPolarHBondContact O-CD2 3.46Å; C445-Y448 PolarHBondContact O-N 3.06Å; C445-N450 HydrophobicContact CB-CB 3.77Å; C445-F468 HydrophobicContact CB-CE2 4.3Å; C445-F468 HydrophobicContact CB-CZ 4.09Å; C445-C488 VanDerWaalsContact CA-SG 3.52Å; C445-C488 HydrophobicContact CB-CB 3.64Å; C445-C488 WeakPolarHBondContact CB-SG 3.4Å; C445-C488 PolarHBondContact O-SG 3.06Å; C445-C488 VanDerWaalsContact O-SG 3.41Å; C445-C488 WeakPolarHBondContact SG-CB 3.4Å; C445-C488 CovalentContact SG-SG 2.01Å; C445-C488 PolarHBondContact SG-SG 3.2Å
446N93.6Very high97.7Very high14 Ų1422.9 Ų22.98%0.07511%0.113CC..THydrogen-bonded Turntrans51.1-117.3-162.4-58.6-31.7000111.7L77 G98 G103 Y444L77-N446 WeakPolarHBondContact CD1-OD1 3.45Å; G98-N446 WeakPolarHBondContact O-CB 3.25Å; G103-N446 WeakPolarHBondContact CA-OD1 3.35Å; Y444-N446 WeakPolarHBondContact CB-O 3.28Å
447S94.9Very high97.5Very high24 Ų2425.3 Ų25.317%0.16813%0.129CC..THydrogen-bonded Turntrans-92.1-2.3176.236.80000114.2G98 N99 C445G98-S447 PolarHBondContact O-OG 3.36Å; G98-S447 VanDerWaalsContact O-OG 3.13Å; N99-S447 PolarHBondContact N-OG 3.45Å; N99-S447 WeakPolarHBondContact OD1-CB 3.48Å; N99-S447 PolarHBondContact OD1-OG 2.93Å; C445-S447 PolarHBondContact O-N 3.13Å
448Y96.5Very high97.2Very high56 Ų5627.7 Ų27.722%0.2214%0.141CC..EExtended strand (participates in β ladder)trans-89.7120.8178.9-56.6-84.6000110N99 Y444 C445 N450 C488N99-Y448 HydrophobicContact CB-CE2 4.35Å; N99-Y448 WeakPolarHBondContact CB-OH 3.23Å; N99-Y448 PolarHBondContact O-OH 2.97Å; Y444-Y448 CarbonylContact C-O 3.53Å; Y444-Y448 WeakPolarHBondContact CA-O 3.48Å; C445-Y448 PolarHBondContact N-O 3.31Å; C445-Y448 WeakPolarHBondContact O-CB 3.17Å; C445-Y448 WeakPolarHBondContact O-CD2 3.46Å; C445-Y448 PolarHBondContact O-N 3.06Å; Y448-N450 PolarHBondContact O-N 2.82Å; Y448-N450 VanDerWaalsContact O-N 3.12Å; Y448-C488 HydrophobicContact CD2-CB 3.61Å; Y448-C488 HydrophobicContact CE2-CB 4.18Å; Y448-C488 HydrophobicContact CG-CB 4.4Å
449L97.8Very high97Very high21 Ų2129.4 Ų29.411%0.1115%0.154CC..EExtended strand (participates in β ladder)trans-68.1111.4171.5179.764.7000108.8F442 Y444 Y467 F468 V533F442-L449 HydrophobicContact CB-CD1 3.98Å; F442-L449 HydrophobicContact CD1-CD1 4.44Å; Y444-L449 HydrophobicContact CD1-CB 4.29Å; Y444-L449 HydrophobicContact CD2-CD1 4.12Å; Y444-L449 HydrophobicContact CE1-CB 3.87Å; Y444-L449 HydrophobicContact CE1-CD1 4.33Å; Y444-L449 HydrophobicContact CE2-CD1 3.82Å; Y444-L449 HydrophobicContact CG-CD1 4.5Å; L449-Y467 HydrophobicContact CD2-CE2 4.33Å; L449-Y467 HydrophobicContact CG-CE2 4.44Å; L449-F468 WeakPolarHBondContact O-CE1 3.4Å; L449-V533 HydrophobicContact CD2-CB 4.25Å; L449-V533 HydrophobicContact CD2-CG1 3.37Å; L449-V533 HydrophobicContact CD2-CG2 3.88Å
450N98.4Very high96.8Very high2 Ų230.3 Ų30.31%0.01117%0.169CC..EExtended strand (participates in β ladder)trans-101.5-45.1-168.4173-115.7000112.9N370 H443 C445 Y448 Y467 F468N370-N450 VanDerWaalsContact CB-OD1 3.28Å; N370-N450 WeakPolarHBondContact CB-OD1 3.29Å; N370-N450 VanDerWaalsContact ND2-CB 3.34Å; N370-N450 WeakPolarHBondContact ND2-CB 3.5Å; N370-N450 PolarHBondContact ND2-OD1 3.13Å; H443-N450 WeakPolarHBondContact O-CB 3.28Å; H443-N450 PolarHBondContact O-N 2.82Å; C445-N450 HydrophobicContact CB-CB 3.77Å; Y448-N450 PolarHBondContact O-N 2.82Å; Y448-N450 VanDerWaalsContact O-N 3.12Å; N450-Y467 PolarHBondContact O-N 2.82Å; N450-F468 VanDerWaalsContact CA-CE1 3.49Å; N450-F468 HydrophobicContact CB-CE1 3.81Å; N450-F468 HydrophobicContact CB-CE2 4.05Å; N450-F468 HydrophobicContact CB-CZ 3.52Å; N450-F468 WeakPolarHBondContact ND2-CD2 3.28Å; N450-F468 WeakPolarHBondContact ND2-CE2 3.29Å; N450-F468 WeakPolarHBondContact ND2-CG 3.42Å; N450-F468 WeakPolarHBondContact ND2-CZ 3.45Å; N450-F468 PolarHBondContact ND2-O 3.27Å
451A98.8Very high96.8Very high0 Ų028.7 Ų28.70%016%0.163CC..EExtended strand (participates in β ladder)trans-141.6161.2177.100000111.2H443 K464 A465 F466H443-A451 WeakPolarHBondContact CA-O 3.44Å; H443-A451 HydrophobicContact CB-CB 4.09Å; H443-A451 PolarHBondContact N-O 3.09Å; H443-A451 PolarHBondContact O-N 3.33Å; H443-A451 VanDerWaalsContact O-N 3.07Å; A451-K464 HydrophobicContact CB-CG 4.5Å; A451-A465 CarbonylContact C-O 3.58Å; A451-A465 WeakPolarHBondContact CA-O 3.4Å; A451-A465 VanDerWaalsContact CB-O 3.28Å; A451-A465 WeakPolarHBondContact CB-O 3.5Å; A451-F466 HydrophobicContact CB-CD1 3.71Å; A451-F466 HydrophobicContact CB-CD2 4.48Å; A451-F466 HydrophobicContact CB-CE1 3.93Å; A451-F466 HydrophobicContact CB-CG 4.02Å; A451-F466 HydrophobicContact CB-CZ 4.42Å
452V98.8Very high96.7Very high0 Ų029 Ų290%017%0.165CC..EExtended strand (participates in β ladder)trans-128.9137.7170.457.50000108.2F440 F442 K464 A465 Y467 M529 V533F440-V452 HydrophobicContact CD1-CG2 4.15Å; F442-V452 HydrophobicContact CD1-CB 4.34Å; F442-V452 HydrophobicContact CD1-CG2 3.81Å; F442-V452 HydrophobicContact CE1-CG2 3.78Å; V452-K464 WeakPolarHBondContact O-CA 3.5Å; V452-A465 HydrophobicContact CG1-CB 4.26Å; V452-A465 PolarHBondContact N-O 3.21Å; V452-A465 PolarHBondContact O-N 2.86Å; V452-Y467 HydrophobicContact CG1-CE2 4.2Å; V452-M529 HydrophobicContact CG1-CB 3.86Å; V452-M529 HydrophobicContact CG1-CE 3.73Å; V452-M529 HydrophobicContact CG1-CG 4.38Å; V452-M529 WeakPolarHBondContact O-CE 3.14Å; V452-V533 HydrophobicContact CB-CG2 4Å; V452-V533 HydrophobicContact CG1-CG2 4.06Å; V452-V533 HydrophobicContact CG2-CG2 4.11Å
453R98.8Very high96.7Very high2 Ų229 Ų291%0.00817%0.165CC..EExtended strand (participates in β ladder)trans-108.5138.4173.2176.4-172.5-67.4168.7-2.9108.7H70 V72 E372 F440 L441 H443 V462 W463H70-R453 PolarHBondContact CD2-NH1 3.23Å; H70-R453 VanDerWaalsContact CD2-NH1 3.26Å; H70-R453 PolarHBondContact NE2-NE 3.23Å; H70-R453 PolarHBondContact NE2-NH1 2.6Å; H70-R453 VanDerWaalsContact NE2-NH1 3.14Å; V72-R453 VanDerWaalsContact CG1-NH2 3.35Å; E372-R453 IonicContact OE1-CZ 3.48Å; E372-R453 IonicContact OE1-NH2 3.7Å; E372-R453 PolarHBondContact OE1-NH2 3.07Å; E372-R453 IonicContact OE2-CZ 3.61Å; E372-R453 IonicContact OE2-NH2 3.48Å; E372-R453 PolarHBondContact OE2-NH2 3.33Å; F440-R453 WeakPolarHBondContact CA-O 3.43Å; L441-R453 HydrophobicContact CB-CB 4.18Å; L441-R453 PolarHBondContact N-O 2.77Å; L441-R453 PolarHBondContact O-N 2.81Å; H443-R453 VanDerWaalsContact NE2-CB 3.29Å; H443-R453 WeakPolarHBondContact NE2-CB 3.32Å; R453-V462 HydrophobicContact CG-CG1 3.51Å; R453-W463 CarbonylContact C-O 3.47Å; R453-W463 VanDerWaalsContact CA-O 3.24Å; R453-W463 WeakPolarHBondContact CA-O 3.36Å
454W98.8Very high96.8Very high37 Ų3728.8 Ų28.814%0.1416%0.164CC..EExtended strand (participates in β ladder)trans-132.9122179.218042.5000110.9E439 F440 P456 W463 I525 A528 M529E439-W454 CarbonylContact O-C 3.53Å; E439-W454 WeakPolarHBondContact O-CA 3.44Å; E439-W454 PolarHBondContact OE1-NE1 2.88Å; F440-W454 HydrophobicContact CD1-CB 3.82Å; F440-W454 AromaticContact CD1-CD1 3.6Å; F440-W454 AromaticContact CD1-CG 3.9Å; F440-W454 HydrophobicContact CD1-CG 3.9Å; F440-W454 AromaticContact CD2-CD1 3.97Å; F440-W454 HydrophobicContact CE1-CB 3.59Å; F440-W454 AromaticContact CE1-CD1 3.13Å; F440-W454 HydrophobicContact CE1-CD2 4.06Å; F440-W454 AromaticContact CE1-CG 3.32Å; F440-W454 HydrophobicContact CE1-CG 3.32Å; F440-W454 AromaticContact CE1-NE1 3.74Å; F440-W454 AromaticContact CE2-CD1 3.54Å; F440-W454 HydrophobicContact CE2-CG 4.48Å; F440-W454 AromaticContact CE2-NE1 3.57Å; F440-W454 HydrophobicContact CZ-CB 4.42Å; F440-W454 AromaticContact CZ-CD1 3.1Å; F440-W454 HydrophobicContact CZ-CD2 4.1Å; F440-W454 AromaticContact CZ-CE2 3.84Å; F440-W454 AromaticContact CZ-CG 3.67Å; F440-W454 HydrophobicContact CZ-CG 3.67Å; F440-W454 AromaticContact CZ-NE1 3.2Å; W454-P456 HydrophobicContact CD2-CB 4.37Å; W454-P456 HydrophobicContact CD2-CG 4.38Å; W454-P456 HydrophobicContact CH2-CB 4.12Å; W454-P456 HydrophobicContact CH2-CG 4.49Å; W454-P456 HydrophobicContact CZ2-CB 3.65Å; W454-P456 HydrophobicContact CZ2-CG 4.36Å; W454-P456 WeakPolarHBondContact O-CD 3.06Å; W454-W463 AromaticContact CE3-CD1 3.62Å; W454-W463 HydrophobicContact CE3-CG 4.34Å; W454-W463 PolarHBondContact N-O 3.31Å; W454-W463 PolarHBondContact O-N 3.12Å; W454-I525 HydrophobicContact CE3-CG2 4.06Å; W454-I525 HydrophobicContact CZ3-CB 4.3Å; W454-I525 HydrophobicContact CZ3-CG1 4.18Å; W454-I525 HydrophobicContact CZ3-CG2 4.1Å; W454-A528 HydrophobicContact CH2-CB 3.89Å; W454-A528 HydrophobicContact CZ2-CB 4.13Å; W454-A528 HydrophobicContact CZ3-CB 4.14Å; W454-M529 HydrophobicContact CB-CE 4.11Å; W454-M529 HydrophobicContact CB-CG 3.96Å; W454-M529 HydrophobicContact CB-SD 4.44Å; W454-M529 HydrophobicContact CE3-CG 4.25Å; W454-M529 HydrophobicContact CG-CG 4.47Å
455H98.4Very high96.8Very high7 Ų728.3 Ų28.33%0.03216%0.162CC..  trans-111.188.5171.1-179.749.8000109.5E395 P396 R435 E439 S459 S461 V462E395-H455 IonicContact OE1-NE2 3.41Å; E395-H455 PolarHBondContact OE1-NE2 3.24Å; E395-H455 IonicContact OE2-CD2 3.87Å; E395-H455 IonicContact OE2-NE2 2.69Å; P396-H455 HydrophobicContact CG-CB 4.01Å; R435-H455 PolarHBondContact NH1-CE1 2.54Å; R435-H455 VanDerWaalsContact NH1-CE1 3.35Å; R435-H455 PolarHBondContact NH1-NE2 3.13Å; E439-H455 PolarHBondContact O-N 2.72Å; H455-S459 PolarHBondContact CE1-O 3.41Å; H455-S461 PolarHBondContact ND1-O 3.22Å; H455-V462 HydrophobicContact CB-CG2 4.27Å
456P97.4Very high96.9Very high15 Ų1528 Ų2810%0.09716%0.16CC..  trans-57.7140-176.516.2-30.4000113.7R435 W454 N458 S459R435-P456 PolarHBondContact NH1-O 2.95Å; W454-P456 HydrophobicContact CD2-CB 4.37Å; W454-P456 HydrophobicContact CD2-CG 4.38Å; W454-P456 HydrophobicContact CH2-CB 4.12Å; W454-P456 HydrophobicContact CH2-CG 4.49Å; W454-P456 HydrophobicContact CZ2-CB 3.65Å; W454-P456 HydrophobicContact CZ2-CG 4.36Å; W454-P456 WeakPolarHBondContact O-CD 3.06Å; P456-N458 PolarHBondContact O-N 3.28Å; P456-S459 PolarHBondContact O-N 3.21Å; P456-S459 VanDerWaalsContact O-N 3.13Å; P456-S459 VanDerWaalsContact O-O 3.13Å
457P92.9Very high97.1Very high67 Ų6729.9 Ų29.944%0.43517%0.166SC..THydrogen-bonded Turntrans-57.8-26.5-174.4-27.734.3000115.8R435 E439R435-P457 PolarHBondContact NH1-O 2.95Å; R435-P457 VanDerWaalsContact NH1-O 3.16Å; R435-P457 PolarHBondContact NH2-O 2.97Å; E439-P457 HydrophobicContact CG-CG 4.46Å
458N90.5Very high97.3Very high163 Ų16329 Ų2987%0.87216%0.16SC*.THydrogen-bonded Turntrans-111.221.4-175.3-64.3-39.8000113.1P456P456-N458 PolarHBondContact O-N 3.28Å
459S94.4Very high97.4Very high41 Ų4127.1 Ų27.129%0.28715%0.154SC..  trans-144.4158.2177.4165.50000110.9R435 H455 P456 S461R435-S459 PolarHBondContact NH1-O 2.87Å; R435-S459 PolarHBondContact NH2-O 3.49Å; H455-S459 PolarHBondContact CE1-O 3.41Å; P456-S459 PolarHBondContact O-N 3.21Å; P456-S459 VanDerWaalsContact O-N 3.13Å; P456-S459 VanDerWaalsContact O-O 3.13Å; S459-S461 WeakPolarHBondContact OG-CB 3.4Å; S459-S461 PolarHBondContact OG-N 3.49Å
460S93.6Very high97.3Very high97 Ų9726.9 Ų26.968%0.67815%0.153SC*.SBendtrans-92-6.1172.161.50000112.2
461S97.4Very high97.2Very high13 Ų1329.6 Ų29.69%0.09117%0.168CC..  trans-65.8146.9175.2-73.30000110.6H455 S459 D503H455-S461 PolarHBondContact ND1-O 3.22Å; S459-S461 WeakPolarHBondContact OG-CB 3.4Å; S459-S461 PolarHBondContact OG-N 3.49Å; S461-D503 PolarHBondContact OG-OD2 3.28Å
462V98.4Very high97Very high8 Ų831.7 Ų31.75%0.04818%0.177CC..  trans-125.2104.1169.8-176.60000107.4P396 R453 H455 D503 L504P396-V462 HydrophobicContact CG-CG1 4.47Å; P396-V462 HydrophobicContact CG-CG2 4.26Å; R453-V462 HydrophobicContact CG-CG1 3.51Å; H455-V462 HydrophobicContact CB-CG2 4.27Å; V462-D503 CarbonylContact O-C 3.58Å; V462-L504 HydrophobicContact CB-CB 4.29Å; V462-L504 HydrophobicContact CG1-CB 4.5Å; V462-L504 HydrophobicContact CG1-CD1 4.26Å; V462-L504 WeakPolarHBondContact O-CB 3.39Å; V462-L504 PolarHBondContact O-N 2.98Å
463W98.8Very high96.7Very high19 Ų1938.4 Ų38.47%0.07220%0.203CC..EExtended strand (participates in β ladder)trans-85.2143.7-178.5-54.9105.9000110.1R453 W454 L501 F502 D503 L514 E519 I525 M529R453-W463 CarbonylContact C-O 3.47Å; R453-W463 VanDerWaalsContact CA-O 3.24Å; R453-W463 WeakPolarHBondContact CA-O 3.36Å; W454-W463 AromaticContact CE3-CD1 3.62Å; W454-W463 HydrophobicContact CE3-CG 4.34Å; W454-W463 PolarHBondContact N-O 3.31Å; W454-W463 PolarHBondContact O-N 3.12Å; W463-L501 HydrophobicContact CB-CD1 4.27Å; W463-F502 CarbonylContact C-O 3.58Å; W463-F502 WeakPolarHBondContact CA-O 3.26Å; W463-D503 HydrophobicContact CE3-CB 3.78Å; W463-D503 HydrophobicContact CH2-CB 4.17Å; W463-D503 HydrophobicContact CZ3-CB 3.47Å; W463-D503 VanDerWaalsContact CZ3-CB 3.47Å; W463-L514 HydrophobicContact CE3-CD1 4.1Å; W463-L514 HydrophobicContact CH2-CD1 4.47Å; W463-L514 HydrophobicContact CZ3-CD1 3.44Å; W463-L514 VanDerWaalsContact CZ3-CD1 3.44Å; W463-E519 HydrophobicContact CH2-CG 4.37Å; W463-E519 WeakPolarHBondContact CH2-OE2 3.33Å; W463-E519 HydrophobicContact CZ3-CG 4.47Å; W463-I525 HydrophobicContact CB-CG2 4.04Å; W463-I525 HydrophobicContact CD2-CD1 3.96Å; W463-I525 HydrophobicContact CD2-CG2 4.23Å; W463-I525 HydrophobicContact CE3-CD1 4.11Å; W463-I525 HydrophobicContact CG-CG2 3.9Å; W463-I525 HydrophobicContact CH2-CD1 3.93Å; W463-I525 HydrophobicContact CZ2-CD1 3.8Å; W463-I525 HydrophobicContact CZ3-CD1 4.06Å; W463-M529 HydrophobicContact CB-CE 4.26Å; W463-M529 HydrophobicContact CB-SD 4.29Å
464K98.8Very high96.3Very high0 Ų040.5 Ų40.50%022%0.217CC..EExtended strand (participates in β ladder)trans-137.1125.3172.3-172.9172.6173.1-163.80110.3N370 E372 A451 V452 F466 L501 F502 L504 E510N370-K464 VanDerWaalsContact O-CE 3.24Å; N370-K464 WeakPolarHBondContact O-CE 3.2Å; N370-K464 PolarHBondContact O-NZ 2.83Å; E372-K464 IonicContact OE1-NZ 2.75Å; E372-K464 PolarHBondContact OE1-NZ 2.85Å; A451-K464 HydrophobicContact CB-CG 4.5Å; V452-K464 WeakPolarHBondContact O-CA 3.5Å; K464-F466 HydrophobicContact CD-CE2 4.02Å; K464-F466 HydrophobicContact CD-CZ 4.26Å; K464-F466 VanDerWaalsContact CE-CZ 3.41Å; K464-F466 HydrophobicContact CG-CE2 4.07Å; K464-L501 CarbonylContact O-C 3.59Å; K464-L501 WeakPolarHBondContact O-CA 3.2Å; K464-F502 PolarHBondContact N-O 2.78Å; K464-F502 PolarHBondContact O-N 2.99Å; K464-L504 HydrophobicContact CB-CD1 4.01Å; K464-L504 HydrophobicContact CB-CD2 4.4Å; K464-L504 HydrophobicContact CB-CG 4.06Å; K464-L504 HydrophobicContact CD-CD1 3.87Å; K464-L504 HydrophobicContact CD-CD2 4.35Å; K464-L504 HydrophobicContact CD-CG 4.46Å; K464-E510 WeakPolarHBondContact CE-OE1 3.28Å; K464-E510 IonicContact NZ-OE1 2.82Å; K464-E510 PolarHBondContact NZ-OE1 3.15Å
465A98.9Very high95.8Very high1 Ų143.2 Ų43.21%0.00825%0.248CC..EExtended strand (participates in β ladder)trans-115.5126.9-179.800000110.2A451 V452 P499 L500 L501 L526 M529A451-A465 CarbonylContact C-O 3.58Å; A451-A465 WeakPolarHBondContact CA-O 3.4Å; A451-A465 VanDerWaalsContact CB-O 3.28Å; A451-A465 WeakPolarHBondContact CB-O 3.5Å; V452-A465 HydrophobicContact CG1-CB 4.26Å; V452-A465 PolarHBondContact N-O 3.21Å; V452-A465 PolarHBondContact O-N 2.86Å; A465-P499 HydrophobicContact CB-CB 4.13Å; A465-L500 CarbonylContact C-O 3.46Å; A465-L500 VanDerWaalsContact CA-O 3.3Å; A465-L500 WeakPolarHBondContact CA-O 3.41Å; A465-L501 HydrophobicContact CB-CD1 4.11Å; A465-L526 HydrophobicContact CB-CD2 3.82Å; A465-M529 HydrophobicContact CB-CE 3.57Å; A465-M529 HydrophobicContact CB-SD 3.85Å
466F98.9Very high95.3Very high0 Ų048.7 Ų48.70%028%0.277CS..EExtended strand (participates in β ladder)trans-99.4125.8174.3-72.6-96.3000110.9N370 W371 A451 K464 T469 P499 L500 F502 E510N370-F466 HydrophobicContact CB-CE1 4.28Å; N370-F466 WeakPolarHBondContact O-CZ 3.35Å; W371-F466 HydrophobicContact CD2-CE1 4.29Å; W371-F466 HydrophobicContact CD2-CE2 4.49Å; W371-F466 AromaticContact CD2-CZ 3.89Å; W371-F466 HydrophobicContact CD2-CZ 3.89Å; W371-F466 HydrophobicContact CE3-CE1 4.24Å; W371-F466 AromaticContact CE3-CE2 3.67Å; W371-F466 HydrophobicContact CE3-CE2 3.67Å; W371-F466 AromaticContact CE3-CZ 3.45Å; W371-F466 HydrophobicContact CE3-CZ 3.45Å; W371-F466 VanDerWaalsContact CE3-CZ 3.45Å; W371-F466 HydrophobicContact CG-CZ 4.47Å; W371-F466 HydrophobicContact CH2-CE2 4.3Å; W371-F466 HydrophobicContact CZ3-CD2 4.13Å; W371-F466 AromaticContact CZ3-CE2 3.55Å; W371-F466 HydrophobicContact CZ3-CE2 3.55Å; W371-F466 AromaticContact CZ3-CZ 3.8Å; W371-F466 HydrophobicContact CZ3-CZ 3.8Å; A451-F466 HydrophobicContact CB-CD1 3.71Å; A451-F466 HydrophobicContact CB-CD2 4.48Å; A451-F466 HydrophobicContact CB-CE1 3.93Å; A451-F466 HydrophobicContact CB-CG 4.02Å; A451-F466 HydrophobicContact CB-CZ 4.42Å; K464-F466 HydrophobicContact CD-CE2 4.02Å; K464-F466 HydrophobicContact CD-CZ 4.26Å; K464-F466 VanDerWaalsContact CE-CZ 3.41Å; K464-F466 HydrophobicContact CG-CE2 4.07Å; F466-T469 HydrophobicContact CB-CG2 4.06Å; F466-T469 HydrophobicContact CD1-CG2 4.11Å; F466-T469 HydrophobicContact CG-CG2 4.14Å; F466-P499 CarbonylContact O-C 3.21Å; F466-P499 WeakPolarHBondContact O-CA 3.03Å; F466-P499 WeakPolarHBondContact O-CB 3.01Å; F466-L500 HydrophobicContact CB-CB 4.24Å; F466-L500 PolarHBondContact N-O 3.42Å; F466-L500 PolarHBondContact O-N 2.81Å; F466-F502 AromaticContact CD2-CD2 3.97Å; F466-F502 HydrophobicContact CD2-CD2 3.97Å; F466-F502 AromaticContact CD2-CE2 3.8Å; F466-F502 HydrophobicContact CD2-CE2 3.8Å; F466-F502 HydrophobicContact CE2-CD2 4.06Å; F466-F502 HydrophobicContact CE2-CE2 4.03Å; F466-E510 WeakPolarHBondContact CE2-OE1 3.32Å
467Y98.8Very high94.9Very high54 Ų5453.2 Ų53.221%0.21230%0.295CS..EExtended strand (participates in β ladder)trans-78.3-29170.7-64.5-68.7000112.1L449 N450 V452 H496 P499 V533L449-Y467 HydrophobicContact CD2-CE2 4.33Å; L449-Y467 HydrophobicContact CG-CE2 4.44Å; N450-Y467 PolarHBondContact O-N 2.82Å; V452-Y467 HydrophobicContact CG1-CE2 4.2Å; Y467-H496 PolarHBondContact O-N 2.01Å; Y467-P499 HydrophobicContact CD1-CB 4.23Å; Y467-P499 HydrophobicContact CD1-CG 3.69Å; Y467-P499 HydrophobicContact CE1-CB 4.37Å; Y467-P499 HydrophobicContact CE1-CG 3.64Å; Y467-V533 HydrophobicContact CE2-CG2 4.25Å; Y467-V533 WeakPolarHBondContact OH-CG2 3.4Å
468F98.6Very high94.9Very high7 Ų752.7 Ų52.73%0.03129%0.291CS..EExtended strand (participates in β ladder)trans-152161.1172.261.4-89000110.4C445 L449 N450 C488 V493 T494 Y495C445-F468 HydrophobicContact CB-CE2 4.3Å; C445-F468 HydrophobicContact CB-CZ 4.09Å; L449-F468 WeakPolarHBondContact O-CE1 3.4Å; N450-F468 VanDerWaalsContact CA-CE1 3.49Å; N450-F468 HydrophobicContact CB-CE1 3.81Å; N450-F468 HydrophobicContact CB-CE2 4.05Å; N450-F468 HydrophobicContact CB-CZ 3.52Å; N450-F468 WeakPolarHBondContact ND2-CD2 3.28Å; N450-F468 WeakPolarHBondContact ND2-CE2 3.29Å; N450-F468 WeakPolarHBondContact ND2-CG 3.42Å; N450-F468 WeakPolarHBondContact ND2-CZ 3.45Å; N450-F468 PolarHBondContact ND2-O 3.27Å; F468-C488 HydrophobicContact CE2-CB 4.49Å; F468-V493 HydrophobicContact CB-CB 4.41Å; F468-V493 HydrophobicContact CB-CG2 4.42Å; F468-V493 HydrophobicContact CD2-CB 3.75Å; F468-V493 HydrophobicContact CD2-CG1 3.7Å; F468-V493 HydrophobicContact CD2-CG2 3.99Å; F468-V493 HydrophobicContact CE2-CB 4.49Å; F468-V493 HydrophobicContact CE2-CG1 4Å; F468-V493 HydrophobicContact CG-CB 4.45Å; F468-V493 HydrophobicContact CG-CG2 4.4Å; F468-T494 CarbonylContact C-O 3.5Å; F468-T494 WeakPolarHBondContact CA-O 3.23Å; F468-T494 VanDerWaalsContact CB-O 3.3Å; F468-T494 WeakPolarHBondContact CB-O 3.34Å; F468-Y495 HydrophobicContact CB-CD1 3.73Å; F468-Y495 HydrophobicContact CB-CE1 4.03Å; F468-Y495 HydrophobicContact CB-CG 4.1Å; F468-Y495 HydrophobicContact CD1-CD1 4.27Å; F468-Y495 AromaticContact CD1-CE1 3.9Å; F468-Y495 HydrophobicContact CD1-CE1 3.9Å; F468-Y495 HydrophobicContact CG-CD1 4.33Å; F468-Y495 HydrophobicContact CG-CE1 4.15Å
469T98Very high95Very high16 Ų1645.4 Ų45.410%0.09825%0.252CS..EExtended strand (participates in β ladder)trans-132.1148.9175.852.70000110.1W371 F466 V493 T494 H496 L500W371-T469 HydrophobicContact CH2-CG2 3.94Å; W371-T469 HydrophobicContact CZ2-CG2 3.49Å; W371-T469 VanDerWaalsContact CZ2-CG2 3.49Å; F466-T469 HydrophobicContact CB-CG2 4.06Å; F466-T469 HydrophobicContact CD1-CG2 4.11Å; F466-T469 HydrophobicContact CG-CG2 4.14Å; T469-V493 CarbonylContact O-C 3.56Å; T469-V493 WeakPolarHBondContact O-CA 3.31Å; T469-T494 PolarHBondContact N-O 3.41Å; T469-T494 PolarHBondContact O-N 3.12Å; T469-H496 WeakPolarHBondContact CG2-NE2 3.46Å; T469-H496 PolarHBondContact OG1-NE2 3.18Å; T469-L500 HydrophobicContact CG2-CD2 4.27Å
470P96.8Very high95Very high15 Ų1543.5 Ų43.510%0.09724%0.239CC..EExtended strand (participates in β ladder)trans-65.1147.917728.9-36000111.6T369 F472 C486T369-P470 HydrophobicContact CG2-CG 4.07Å; P470-F472 HydrophobicContact CG-CD1 4.28Å; P470-F472 HydrophobicContact CG-CE1 3.71Å; P470-F472 HydrophobicContact CG-CZ 4.15Å; P470-F472 PolarHBondContact O-N 2.9Å; P470-C486 HydrophobicContact CB-CB 3.79Å; P470-C486 HydrophobicContact CG-CB 4.37Å
471D95.4Very high94.8Very high59 Ų5942 Ų4232%0.31622%0.22SC..  trans-81.1100.4173.8-61.7-27.6000109.5H492 V493 T494D471-H492 PolarHBondContact N-O 2.99Å; D471-V493 PolarHBondContact OD2-N 2.89Å; D471-V493 VanDerWaalsContact OD2-N 3.15Å; D471-T494 PolarHBondContact OD1-N 2.86Å; D471-T494 PolarHBondContact OD1-OG1 3.37Å
472F95.8Very high94.3Very high44 Ų4445 Ų4519%0.19323%0.233CC..  trans-68.3144-179-65.8-43.1000112.6A365 T369 W371 P470 K477 T478 T479A365-F472 HydrophobicContact CB-CE1 4.23Å; A365-F472 HydrophobicContact CB-CZ 3.95Å; T369-F472 HydrophobicContact CG2-CE1 4.48Å; W371-F472 AromaticContact CD1-CZ 3.57Å; W371-F472 AromaticContact NE1-CE2 3.82Å; W371-F472 AromaticContact NE1-CZ 3.26Å; W371-F472 VanDerWaalsContact NE1-CZ 3.26Å; P470-F472 HydrophobicContact CG-CD1 4.28Å; P470-F472 HydrophobicContact CG-CE1 3.71Å; P470-F472 HydrophobicContact CG-CZ 4.15Å; P470-F472 PolarHBondContact O-N 2.9Å; F472-K477 VanDerWaalsContact CB-O 3.27Å; F472-K477 WeakPolarHBondContact CB-O 3.27Å; F472-K477 WeakPolarHBondContact CD2-O 3.07Å; F472-K477 WeakPolarHBondContact CG-O 3.48Å; F472-T478 VanDerWaalsContact CE1-C 3.48Å; F472-T478 WeakPolarHBondContact CE1-O 3.42Å; F472-T478 HydrophobicContact CE2-CG2 4.2Å; F472-T479 WeakPolarHBondContact CA-O 3.08Å
473Y91.1Very high93.8Very high142 Ų14246.1 Ų46.156%0.55724%0.24SC*.BIsolated β-bridgetrans-143.3127.5171.9-172.5-90.2000111.6T479 F481 H482Y473-T479 CarbonylContact C-O 3.52Å; Y473-T479 PolarHBondContact N-O 3.33Å; Y473-F481 PolarHBondContact O-N 2.97Å; Y473-H482 VanDerWaalsContact CB-ND1 3.3Å; Y473-H482 WeakPolarHBondContact CB-ND1 3.44Å; Y473-H482 HydrophobicContact CD1-CB 3.66Å; Y473-H482 HydrophobicContact CE1-CB 4.3Å; Y473-H482 HydrophobicContact CG-CB 4.02Å
474P91Very high93.3Very high45 Ų4547.1 Ų47.129%0.29225%0.245SC..SBendcis-69.3155.8-2.930.5-33.5000111.7D476 K477P474-D476 WeakPolarHBondContact CB-OD1 3.3Å; P474-D476 WeakPolarHBondContact CG-OD1 3.11Å; P474-D476 PolarHBondContact O-N 3.23Å; P474-D476 VanDerWaalsContact O-N 3.11Å; P474-K477 HydrophobicContact CG-CB 4.27Å; P474-K477 HydrophobicContact CG-CG 3.66Å; P474-K477 WeakPolarHBondContact O-CB 3.28Å; P474-K477 PolarHBondContact O-N 3.05Å
475A88.1Confident93Very high95 Ų9548.7 Ų48.779%0.78526%0.255SS*.THydrogen-bonded Turntrans-64.7-17.5-167.900000114.5K477A475-K477 VanDerWaalsContact C-N 3.28Å
476D87.7Confident92.7Very high122 Ų12248.9 Ų48.965%0.65226%0.256SS*.THydrogen-bonded Turntrans-851174.868.4-50.8000113.3P474P474-D476 WeakPolarHBondContact CB-OD1 3.3Å; P474-D476 WeakPolarHBondContact CG-OD1 3.11Å; P474-D476 PolarHBondContact O-N 3.23Å; P474-D476 VanDerWaalsContact O-N 3.11Å
477K90.1Very high92.5Very high110 Ų11050 Ų5048%0.47826%0.261SS..SBendtrans-118166.6179.5-57.7-65.3178.5-173.50110.9F472 P474 A475 T479F472-K477 VanDerWaalsContact CB-O 3.27Å; F472-K477 WeakPolarHBondContact CB-O 3.27Å; F472-K477 WeakPolarHBondContact CD2-O 3.07Å; F472-K477 WeakPolarHBondContact CG-O 3.48Å; P474-K477 HydrophobicContact CG-CB 4.27Å; P474-K477 HydrophobicContact CG-CG 3.66Å; P474-K477 WeakPolarHBondContact O-CB 3.28Å; P474-K477 PolarHBondContact O-N 3.05Å; A475-K477 VanDerWaalsContact C-N 3.28Å; K477-T479 WeakPolarHBondContact CB-OG1 3.33Å
478T91.9Very high92.2Very high55 Ų5547.7 Ų47.734%0.33725%0.252SS..SBendtrans-104.738.5178.850.60000111.4K364 A365 F472K364-T478 HydrophobicContact CG-CG2 3.9Å; A365-T478 WeakPolarHBondContact CA-O 3.36Å; A365-T478 WeakPolarHBondContact CB-O 3.04Å; F472-T478 VanDerWaalsContact CE1-C 3.48Å; F472-T478 WeakPolarHBondContact CE1-O 3.42Å; F472-T478 HydrophobicContact CE2-CG2 4.2Å
479T93.2Very high91.9Very high10 Ų1048.1 Ų48.16%0.06126%0.256CS..SBendtrans-139.3158.7-168.555.90000111.3L346 E347 F472 Y473 K477 F481L346-T479 HydrophobicContact CB-CG2 3.69Å; L346-T479 HydrophobicContact CD1-CG2 4.09Å; E347-T479 WeakPolarHBondContact OE1-CA 3.34Å; F472-T479 WeakPolarHBondContact CA-O 3.08Å; Y473-T479 CarbonylContact C-O 3.52Å; Y473-T479 PolarHBondContact N-O 3.33Å; K477-T479 WeakPolarHBondContact CB-OG1 3.33Å; T479-F481 HydrophobicContact CG2-CE2 3.92Å; T479-F481 HydrophobicContact CG2-CZ 4.38Å; T479-F481 WeakPolarHBondContact OG1-CD2 3.48Å; T479-F481 WeakPolarHBondContact OG1-CE2 3.41Å
480C93.3Very high91.6Very high2 Ų250.9 Ų50.91%0.01427%0.274CS..BIsolated β-bridgetrans-113.558.9175.7-62.30000112.7E347 H482 T483 H484 C486E347-C480 PolarHBondContact OE1-N 3.01Å; C480-H482 PolarHBondContact O-N 3.4Å; C480-H482 VanDerWaalsContact O-N 3.15Å; C480-T483 PolarHBondContact O-N 3.06Å; C480-T483 PolarHBondContact O-OG1 2.9Å; C480-H484 PolarHBondContact O-N 2.63Å; C480-C486 HydrophobicContact CB-CB 3.94Å; C480-C486 WeakPolarHBondContact CB-SG 3.44Å; C480-C486 WeakPolarHBondContact SG-CA 3.13Å; C480-C486 WeakPolarHBondContact SG-CB 3.22Å; C480-C486 CovalentContact SG-SG 2.04Å; C480-C486 PolarHBondContact SG-SG 2.89Å
481F89.6Confident91.4Very high64 Ų6456.3 Ų56.328%0.28130%0.302SS..THydrogen-bonded Turntrans-59.6-30.4-175.9-77.9-71.5000114.2E347 L349 Y473 T479 T483 H484E347-F481 VanDerWaalsContact CA-CE1 3.48Å; E347-F481 HydrophobicContact CB-CD1 4.16Å; E347-F481 HydrophobicContact CB-CE1 4.29Å; E347-F481 HydrophobicContact CG-CD1 4.47Å; L349-F481 HydrophobicContact CD1-CD1 3.88Å; L349-F481 HydrophobicContact CD1-CE1 3.97Å; L349-F481 HydrophobicContact CD2-CD1 4.45Å; L349-F481 HydrophobicContact CD2-CE1 3.69Å; L349-F481 HydrophobicContact CD2-CZ 4.45Å; L349-F481 HydrophobicContact CG-CD1 4.16Å; L349-F481 HydrophobicContact CG-CE1 3.82Å; Y473-F481 PolarHBondContact O-N 2.97Å; T479-F481 HydrophobicContact CG2-CE2 3.92Å; T479-F481 HydrophobicContact CG2-CZ 4.38Å; T479-F481 WeakPolarHBondContact OG1-CD2 3.48Å; T479-F481 WeakPolarHBondContact OG1-CE2 3.41Å; F481-T483 VanDerWaalsContact C-N 3.3Å; F481-T483 PolarHBondContact O-N 3.07Å; F481-H484 PolarHBondContact O-N 2.84Å
482H88.2Confident91.4Very high76 Ų7654.9 Ų54.935%0.35229%0.293SS..THydrogen-bonded Turntrans-58.8-39.8178.866.1-58.2000113.2K185 Y473 C480K185-H482 PolarHBondContact NZ-O 2.6Å; Y473-H482 VanDerWaalsContact CB-ND1 3.3Å; Y473-H482 WeakPolarHBondContact CB-ND1 3.44Å; Y473-H482 HydrophobicContact CD1-CB 3.66Å; Y473-H482 HydrophobicContact CE1-CB 4.3Å; Y473-H482 HydrophobicContact CG-CB 4.02Å; C480-H482 PolarHBondContact O-N 3.4Å; C480-H482 VanDerWaalsContact O-N 3.15Å
483T87.8Confident91.4Very high32 Ų3253.2 Ų53.220%0.19629%0.287CS..THydrogen-bonded Turntrans-105-1.8-179.145.60000113.5C480 F481 V485 F487C480-T483 PolarHBondContact O-N 3.06Å; C480-T483 PolarHBondContact O-OG1 2.9Å; F481-T483 VanDerWaalsContact C-N 3.3Å; F481-T483 PolarHBondContact O-N 3.07Å; T483-V485 VanDerWaalsContact CB-O 3.31Å; T483-V485 WeakPolarHBondContact CB-O 3.35Å; T483-V485 PolarHBondContact O-N 2.86Å; T483-V485 PolarHBondContact OG1-O 3.13Å; T483-F487 HydrophobicContact CG2-CD2 4.01Å; T483-F487 HydrophobicContact CG2-CE2 3.66Å
484H88.1Confident91.7Very high41 Ų4149.7 Ų49.719%0.1928%0.28CS..SBendtrans66.7-20.3-175.4-176.7-115.3000115H345 E347 E348 C480 F481H345-H484 AromaticContact CE1-CE1 3.46Å; H345-H484 PolarHBondContact CE1-CE1 2.73Å; H345-H484 VanDerWaalsContact CE1-CE1 3.46Å; H345-H484 AromaticContact CE1-NE2 3.61Å; H345-H484 AromaticContact NE2-NE2 3.97Å; H345-H484 PolarHBondContact NE2-O 3.08Å; E347-H484 WeakPolarHBondContact CB-O 3.37Å; E348-H484 IonicContact OE2-CE1 3.45Å; E348-H484 PolarHBondContact OE2-CE1 2.84Å; E348-H484 IonicContact OE2-NE2 2.79Å; E348-H484 PolarHBondContact OE2-NE2 3.48Å; C480-H484 PolarHBondContact O-N 2.63Å; F481-H484 PolarHBondContact O-N 2.84Å
485V91.1Very high92.1Very high32 Ų3253.6 Ų53.619%0.19429%0.29CS..SBendtrans-144.1155.8167.9-67.90000109.1T483 F487T483-V485 VanDerWaalsContact CB-O 3.31Å; T483-V485 WeakPolarHBondContact CB-O 3.35Å; T483-V485 PolarHBondContact O-N 2.86Å; T483-V485 PolarHBondContact OG1-O 3.13Å; V485-F487 HydrophobicContact CG2-CD1 4.28Å; V485-F487 HydrophobicContact CG2-CE1 3.67Å; V485-F487 HydrophobicContact CG2-CZ 4.11Å
486C93.9Very high92.6Very high5 Ų551.3 Ų51.33%0.03426%0.263CS..  trans-77.8135.4172.9-61.20000110.7S368 T369 P470 C480S368-C486 WeakPolarHBondContact CB-O 3.37Å; S368-C486 PolarHBondContact OG-N 2.91Å; T369-C486 HydrophobicContact CG2-CB 3.78Å; T369-C486 VanDerWaalsContact CG2-SG 3.54Å; P470-C486 HydrophobicContact CB-CB 3.79Å; P470-C486 HydrophobicContact CG-CB 4.37Å; C480-C486 HydrophobicContact CB-CB 3.94Å; C480-C486 WeakPolarHBondContact CB-SG 3.44Å; C480-C486 WeakPolarHBondContact SG-CA 3.13Å; C480-C486 WeakPolarHBondContact SG-CB 3.22Å; C480-C486 CovalentContact SG-SG 2.04Å; C480-C486 PolarHBondContact SG-SG 2.89Å
487F94.1Very high93Very high25 Ų2553.2 Ų53.211%0.1127%0.273CS..  trans-100.9156.2177.1-64.4-50.1000111.7R101 T483 V485 H492 V493R101-F487 HydrophobicContact CB-CD1 4.02Å; R101-F487 HydrophobicContact CB-CE1 3.82Å; R101-F487 HydrophobicContact CB-CZ 4.13Å; R101-F487 HydrophobicContact CG-CD1 4.35Å; R101-F487 HydrophobicContact CG-CD2 4.4Å; R101-F487 HydrophobicContact CG-CE1 4.44Å; R101-F487 HydrophobicContact CG-CE2 4.47Å; R101-F487 HydrophobicContact CG-CG 4.35Å; T483-F487 HydrophobicContact CG2-CD2 4.01Å; T483-F487 HydrophobicContact CG2-CE2 3.66Å; V485-F487 HydrophobicContact CG2-CD1 4.28Å; V485-F487 HydrophobicContact CG2-CE1 3.67Å; V485-F487 HydrophobicContact CG2-CZ 4.11Å; F487-H492 HydrophobicContact CB-CB 4.06Å; F487-H492 AromaticContact CD2-CD2 3.86Å; F487-H492 AromaticContact CD2-NE2 3.89Å; F487-V493 VanDerWaalsContact O-CG1 3.28Å; F487-V493 WeakPolarHBondContact O-CG1 3.33Å
488C92.8Very high93.4Very high5 Ų550.9 Ų50.93%0.03427%0.269CS..  trans-95-3.5178.4-42.20000113.4C445 Y448 F468C445-C488 VanDerWaalsContact CA-SG 3.52Å; C445-C488 HydrophobicContact CB-CB 3.64Å; C445-C488 WeakPolarHBondContact CB-SG 3.4Å; C445-C488 PolarHBondContact O-SG 3.06Å; C445-C488 VanDerWaalsContact O-SG 3.41Å; C445-C488 WeakPolarHBondContact SG-CB 3.4Å; C445-C488 CovalentContact SG-SG 2.01Å; C445-C488 PolarHBondContact SG-SG 3.2Å; Y448-C488 HydrophobicContact CD2-CB 3.61Å; Y448-C488 HydrophobicContact CE2-CB 4.18Å; Y448-C488 HydrophobicContact CG-CB 4.4Å; F468-C488 HydrophobicContact CE2-CB 4.49Å
489T92.3Very high93.7Very high16 Ų1649.3 Ų49.310%0.09826%0.26CS..SBendtrans-77.7150.7-173.155.80000111.5R101 D491 H492R101-T489 HydrophobicContact CG-CG2 4.31Å; T489-D491 PolarHBondContact O-N 2.04Å; T489-H492 PolarHBondContact O-N 2.8Å; T489-H492 PolarHBondContact OG1-ND1 2.83Å
490P91.4Very high93.9Very high73 Ų7350.8 Ų50.847%0.47427%0.267SS..G310 helixtrans-49.6-33.1-176.4-30.635.9000116H492 Y495P490-H492 PolarHBondContact O-N 2.79Å; P490-Y495 HydrophobicContact CB-CE2 4.46Å
491D92.8Very high94.2Very high129 Ų12950.7 Ų50.769%0.6927%0.267SS*.G310 helixtrans-73.7-4.7-178.9-55.4-33.9000114.8T489T489-D491 PolarHBondContact O-N 2.04Å
492H94.4Very high94.6Very high29 Ų2947.8 Ų47.813%0.13425%0.254CS..G310 helixtrans-133.314.7-174.2-58.179000112.5D471 F487 T489 P490D471-H492 PolarHBondContact N-O 2.99Å; F487-H492 HydrophobicContact CB-CB 4.06Å; F487-H492 AromaticContact CD2-CD2 3.86Å; F487-H492 AromaticContact CD2-NE2 3.89Å; T489-H492 PolarHBondContact O-N 2.8Å; T489-H492 PolarHBondContact OG1-ND1 2.83Å; P490-H492 PolarHBondContact O-N 2.79Å
493V97Very high95.1Very high10 Ų1044.5 Ų44.56%0.06124%0.239CC..EExtended strand (participates in β ladder)trans-137.7147.7-177.1-56.80000111.1F468 T469 D471 F487 Y495F468-V493 HydrophobicContact CB-CB 4.41Å; F468-V493 HydrophobicContact CB-CG2 4.42Å; F468-V493 HydrophobicContact CD2-CB 3.75Å; F468-V493 HydrophobicContact CD2-CG1 3.7Å; F468-V493 HydrophobicContact CD2-CG2 3.99Å; F468-V493 HydrophobicContact CE2-CB 4.49Å; F468-V493 HydrophobicContact CE2-CG1 4Å; F468-V493 HydrophobicContact CG-CB 4.45Å; F468-V493 HydrophobicContact CG-CG2 4.4Å; T469-V493 CarbonylContact O-C 3.56Å; T469-V493 WeakPolarHBondContact O-CA 3.31Å; D471-V493 PolarHBondContact OD2-N 2.89Å; D471-V493 VanDerWaalsContact OD2-N 3.15Å; F487-V493 VanDerWaalsContact O-CG1 3.28Å; F487-V493 WeakPolarHBondContact O-CG1 3.33Å; V493-Y495 HydrophobicContact CG2-CD2 4.21Å; V493-Y495 HydrophobicContact CG2-CE2 3.64Å
494T97.7Very high95.6Very high67 Ų6743.3 Ų43.341%0.41123%0.231SC..EExtended strand (participates in β ladder)trans-102.1123169.7-64.30000109.5F468 T469 D471 H496F468-T494 CarbonylContact C-O 3.5Å; F468-T494 WeakPolarHBondContact CA-O 3.23Å; F468-T494 VanDerWaalsContact CB-O 3.3Å; F468-T494 WeakPolarHBondContact CB-O 3.34Å; T469-T494 PolarHBondContact N-O 3.41Å; T469-T494 PolarHBondContact O-N 3.12Å; D471-T494 PolarHBondContact OD1-N 2.86Å; D471-T494 PolarHBondContact OD1-OG1 3.37Å; T494-H496 PolarHBondContact O-NE2 2.97Å
495Y98.4Very high96Very high127 Ų12744.1 Ų44.150%0.49824%0.242SC..EExtended strand (participates in β ladder)trans-84.5147.8175.3-70.1-89.9000111.8F468 P490 V493F468-Y495 HydrophobicContact CB-CD1 3.73Å; F468-Y495 HydrophobicContact CB-CE1 4.03Å; F468-Y495 HydrophobicContact CB-CG 4.1Å; F468-Y495 HydrophobicContact CD1-CD1 4.27Å; F468-Y495 AromaticContact CD1-CE1 3.9Å; F468-Y495 HydrophobicContact CD1-CE1 3.9Å; F468-Y495 HydrophobicContact CG-CD1 4.33Å; F468-Y495 HydrophobicContact CG-CE1 4.15Å; P490-Y495 HydrophobicContact CB-CE2 4.46Å; V493-Y495 HydrophobicContact CG2-CD2 4.21Å; V493-Y495 HydrophobicContact CG2-CE2 3.64Å
496H98.3Very high96.3Very high47 Ų4749.6 Ų49.622%0.21826%0.263CS..EExtended strand (participates in β ladder)trans-121.8126.6-176.6-56.8-65.7000111.3Y467 T469 T494 P498 L500Y467-H496 PolarHBondContact O-N 2.01Å; T469-H496 WeakPolarHBondContact CG2-NE2 3.46Å; T469-H496 PolarHBondContact OG1-NE2 3.18Å; T494-H496 PolarHBondContact O-NE2 2.97Å; H496-P498 CarbonylContact C-O 3.42Å; H496-L500 HydrophobicContact CB-CB 4.41Å
497D96.9Very high96.5Very high162 Ų16250.4 Ų50.487%0.86627%0.267SS*.EExtended strand (participates in β ladder)trans-139.7110.1171.4-171.716.7000109.9
498P97.6Very high96.6Very high62 Ų6251 Ų5140%0.40327%0.273SS..EExtended strand (participates in β ladder)cis-65160.1-1.628.9-35.5000113H496 F522 L526H496-P498 CarbonylContact C-O 3.42Å; P498-F522 HydrophobicContact CB-CE1 4.1Å; P498-F522 HydrophobicContact CB-CZ 4.37Å; P498-F522 HydrophobicContact CG-CE1 3.85Å; P498-F522 HydrophobicContact CG-CZ 4.09Å; P498-L526 HydrophobicContact CB-CD1 3.87Å
499P98.5Very high96.9Very high21 Ų2152.6 Ų52.614%0.13628%0.284CS..EExtended strand (participates in β ladder)trans-54.6145.8176.5-27.535.3000113.5A465 F466 Y467 L501 L526A465-P499 HydrophobicContact CB-CB 4.13Å; F466-P499 CarbonylContact O-C 3.21Å; F466-P499 WeakPolarHBondContact O-CA 3.03Å; F466-P499 WeakPolarHBondContact O-CB 3.01Å; Y467-P499 HydrophobicContact CD1-CB 4.23Å; Y467-P499 HydrophobicContact CD1-CG 3.69Å; Y467-P499 HydrophobicContact CE1-CB 4.37Å; Y467-P499 HydrophobicContact CE1-CG 3.64Å; P499-L501 PolarHBondContact O-N 3.21Å; P499-L526 HydrophobicContact CB-CD2 4.03Å; P499-L526 HydrophobicContact CG-CD2 4.37Å
500L98.5Very high97.1Very high42 Ų4251.9 Ų51.922%0.2228%0.28CS..EExtended strand (participates in β ladder)trans-74.2114.8-180-170.571.3000110.2W371 A465 F466 T469 H496 F502 P513W371-L500 HydrophobicContact CH2-CD2 4.12Å; A465-L500 CarbonylContact C-O 3.46Å; A465-L500 VanDerWaalsContact CA-O 3.3Å; A465-L500 WeakPolarHBondContact CA-O 3.41Å; F466-L500 HydrophobicContact CB-CB 4.24Å; F466-L500 PolarHBondContact N-O 3.42Å; F466-L500 PolarHBondContact O-N 2.81Å; T469-L500 HydrophobicContact CG2-CD2 4.27Å; H496-L500 HydrophobicContact CB-CB 4.41Å; L500-F502 HydrophobicContact CB-CE2 4.41Å; L500-F502 HydrophobicContact CD2-CE2 3.58Å; L500-F502 HydrophobicContact CD2-CZ 3.59Å; L500-F502 HydrophobicContact CG-CE2 3.6Å; L500-F502 HydrophobicContact CG-CZ 3.81Å; L500-P513 HydrophobicContact CD1-CB 3.34Å; L500-P513 HydrophobicContact CD1-CG 3.98Å; L500-P513 HydrophobicContact CG-CB 3.91Å
501L98.8Very high97.4Very high0 Ų051.6 Ų51.60%028%0.28CS..EExtended strand (participates in β ladder)trans-103.6140.2-171.5-174.365.6000112.6W463 K464 A465 P499 P513 L514 F522 I525 L526 M529W463-L501 HydrophobicContact CB-CD1 4.27Å; K464-L501 CarbonylContact O-C 3.59Å; K464-L501 WeakPolarHBondContact O-CA 3.2Å; A465-L501 HydrophobicContact CB-CD1 4.11Å; P499-L501 PolarHBondContact O-N 3.21Å; L501-P513 CarbonylContact O-C 3.52Å; L501-P513 WeakPolarHBondContact O-CA 3.39Å; L501-L514 HydrophobicContact CB-CB 4.45Å; L501-L514 HydrophobicContact CG-CD1 4.5Å; L501-L514 PolarHBondContact O-N 3.13Å; L501-F522 HydrophobicContact CB-CD2 4.3Å; L501-F522 HydrophobicContact CB-CE2 3.75Å; L501-F522 HydrophobicContact CD2-CD2 3.67Å; L501-F522 HydrophobicContact CD2-CE2 3.98Å; L501-F522 HydrophobicContact CD2-CG 4.49Å; L501-I525 HydrophobicContact CD1-CG2 3.92Å; L501-I525 HydrophobicContact CD2-CB 4.35Å; L501-I525 HydrophobicContact CD2-CD1 4.31Å; L501-I525 HydrophobicContact CD2-CG2 3.99Å; L501-L526 HydrophobicContact CB-CD2 4.45Å; L501-L526 HydrophobicContact CD1-CD2 4.2Å; L501-M529 HydrophobicContact CD1-SD 4.06Å
502F98.8Very high97.5Very high2 Ų254.6 Ų54.61%0.00928%0.281CS..EExtended strand (participates in β ladder)trans-133.2150.2173.8-60.2-90.8000111.1W371 W463 K464 F466 L500 L504 E510 P513W371-F502 AromaticContact CH2-CE2 3.91Å; W371-F502 HydrophobicContact CH2-CE2 3.91Å; W371-F502 AromaticContact CH2-CZ 3.77Å; W371-F502 HydrophobicContact CH2-CZ 3.77Å; W371-F502 HydrophobicContact CZ3-CD2 4.43Å; W371-F502 HydrophobicContact CZ3-CE1 4.45Å; W371-F502 AromaticContact CZ3-CE2 3.61Å; W371-F502 HydrophobicContact CZ3-CE2 3.61Å; W371-F502 AromaticContact CZ3-CZ 3.63Å; W371-F502 HydrophobicContact CZ3-CZ 3.63Å; W463-F502 CarbonylContact C-O 3.58Å; W463-F502 WeakPolarHBondContact CA-O 3.26Å; K464-F502 PolarHBondContact N-O 2.78Å; K464-F502 PolarHBondContact O-N 2.99Å; F466-F502 AromaticContact CD2-CD2 3.97Å; F466-F502 HydrophobicContact CD2-CD2 3.97Å; F466-F502 AromaticContact CD2-CE2 3.8Å; F466-F502 HydrophobicContact CD2-CE2 3.8Å; F466-F502 HydrophobicContact CE2-CD2 4.06Å; F466-F502 HydrophobicContact CE2-CE2 4.03Å; L500-F502 HydrophobicContact CB-CE2 4.41Å; L500-F502 HydrophobicContact CD2-CE2 3.58Å; L500-F502 HydrophobicContact CD2-CZ 3.59Å; L500-F502 HydrophobicContact CG-CE2 3.6Å; L500-F502 HydrophobicContact CG-CZ 3.81Å; F502-L504 HydrophobicContact CB-CD2 4.47Å; F502-E510 HydrophobicContact CD1-CB 4.09Å; F502-E510 HydrophobicContact CE1-CB 4.14Å; F502-E510 WeakPolarHBondContact CE1-O 3.44Å; F502-E510 HydrophobicContact CG-CB 4.42Å; F502-E510 HydrophobicContact CG-CG 4.47Å; F502-P513 HydrophobicContact CD1-CB 4.48Å; F502-P513 HydrophobicContact CE1-CB 3.84Å; F502-P513 HydrophobicContact CZ-CB 3.9Å
503D98.4Very high97.7Very high7 Ų756.1 Ų56.14%0.03729%0.294CS..EExtended strand (participates in β ladder)trans-103.496.7165.8-170.7-10.6000109S461 V462 W463 S505 K506 D507 L514S461-D503 PolarHBondContact OG-OD2 3.28Å; V462-D503 CarbonylContact O-C 3.58Å; W463-D503 HydrophobicContact CE3-CB 3.78Å; W463-D503 HydrophobicContact CH2-CB 4.17Å; W463-D503 HydrophobicContact CZ3-CB 3.47Å; W463-D503 VanDerWaalsContact CZ3-CB 3.47Å; D503-S505 VanDerWaalsContact CG-OG 3.3Å; D503-S505 PolarHBondContact O-N 2.93Å; D503-S505 WeakPolarHBondContact OD1-CB 3.47Å; D503-S505 PolarHBondContact OD1-N 3.32Å; D503-S505 PolarHBondContact OD1-OG 3.47Å; D503-S505 PolarHBondContact OD2-OG 2.88Å; D503-K506 HydrophobicContact CB-CB 4.49Å; D503-K506 PolarHBondContact O-N 3.46Å; D503-K506 WeakPolarHBondContact OD2-CD 3.34Å; D503-K506 VanDerWaalsContact OD2-CE 3.28Å; D503-K506 WeakPolarHBondContact OD2-CE 2.96Å; D503-K506 IonicContact OD2-NZ 2.97Å; D503-K506 PolarHBondContact OD2-NZ 2.91Å; D503-D507 PolarHBondContact O-N 2.8Å; D503-L514 HydrophobicContact CB-CD1 4.05Å
504L98.3Very high97.8Very high8 Ų857.3 Ų57.34%0.04230%0.299CS..THydrogen-bonded Turntrans-64.8-20.3-177.6-60.2-177.9000113E372 V462 K464 F502 K506 E510E372-L504 HydrophobicContact CG-CD1 4.34Å; E372-L504 HydrophobicContact CG-CD2 3.99Å; V462-L504 HydrophobicContact CB-CB 4.29Å; V462-L504 HydrophobicContact CG1-CB 4.5Å; V462-L504 HydrophobicContact CG1-CD1 4.26Å; V462-L504 WeakPolarHBondContact O-CB 3.39Å; V462-L504 PolarHBondContact O-N 2.98Å; K464-L504 HydrophobicContact CB-CD1 4.01Å; K464-L504 HydrophobicContact CB-CD2 4.4Å; K464-L504 HydrophobicContact CB-CG 4.06Å; K464-L504 HydrophobicContact CD-CD1 3.87Å; K464-L504 HydrophobicContact CD-CD2 4.35Å; K464-L504 HydrophobicContact CD-CG 4.46Å; F502-L504 HydrophobicContact CB-CD2 4.47Å; L504-K506 PolarHBondContact O-N 3.44Å; L504-E510 HydrophobicContact CD2-CG 3.53Å
505S96.9Very high97.8Very high58 Ų5856.9 Ų56.941%0.40630%0.297SS..THydrogen-bonded Turntrans-69.9-24.3175.673.90000112.4D503D503-S505 VanDerWaalsContact CG-OG 3.3Å; D503-S505 PolarHBondContact O-N 2.93Å; D503-S505 WeakPolarHBondContact OD1-CB 3.47Å; D503-S505 PolarHBondContact OD1-N 3.32Å; D503-S505 PolarHBondContact OD1-OG 3.47Å; D503-S505 PolarHBondContact OD2-OG 2.88Å
506K96.9Very high97.7Very high146 Ų14652.9 Ų52.964%0.63529%0.29SS*.THydrogen-bonded Turntrans-109.7-34.1179.9-64176.6-169.2134.10112.9D503 L504D503-K506 HydrophobicContact CB-CB 4.49Å; D503-K506 PolarHBondContact O-N 3.46Å; D503-K506 WeakPolarHBondContact OD2-CD 3.34Å; D503-K506 VanDerWaalsContact OD2-CE 3.28Å; D503-K506 WeakPolarHBondContact OD2-CE 2.96Å; D503-K506 IonicContact OD2-NZ 2.97Å; D503-K506 PolarHBondContact OD2-NZ 2.91Å; L504-K506 PolarHBondContact O-N 3.44Å
507D97.9Very high97.6Very high23 Ų2358.2 Ų58.212%0.12332%0.32CS..  trans-129.674.4179.9-178.223.3000110.9D503 S509 E510 S511 R512D503-D507 PolarHBondContact O-N 2.8Å; D507-S509 PolarHBondContact O-N 3.47Å; D507-S509 VanDerWaalsContact O-N 3.13Å; D507-S509 PolarHBondContact OD1-N 3.25Å; D507-S509 PolarHBondContact OD1-OG 2.98Å; D507-E510 PolarHBondContact O-N 2.9Å; D507-E510 VanDerWaalsContact O-N 3.14Å; D507-E510 PolarHBondContact OD1-N 3.07Å; D507-S511 PolarHBondContact OD1-OG 2.9Å; D507-S511 VanDerWaalsContact OD1-OG 3.12Å; D507-S511 PolarHBondContact OD2-N 3.03Å; D507-S511 PolarHBondContact OD2-OG 3.34Å; D507-R512 PolarHBondContact OD2-N 2.98Å
508P97.2Very high97.6Very high38 Ų3854.7 Ų54.725%0.24731%0.305CS..THydrogen-bonded Turntrans-62.6-16.2174.425.6-35.2000113I362 Y363 E510I362-P508 HydrophobicContact CD1-CB 4.05Å; I362-P508 HydrophobicContact CD1-CG 3.64Å; Y363-P508 HydrophobicContact CD1-CB 4.39Å; Y363-P508 WeakPolarHBondContact CD1-O 3.48Å; Y363-P508 HydrophobicContact CE1-CB 3.93Å; P508-E510 VanDerWaalsContact C-N 3.32Å
509S97.3Very high97.6Very high38 Ų3853.2 Ų53.227%0.26629%0.293SS..THydrogen-bonded Turntrans-83.4-5.217873.70000114I362 K364 D507 S511I362-S509 WeakPolarHBondContact O-CA 3.34Å; I362-S509 VanDerWaalsContact O-CB 3.28Å; I362-S509 WeakPolarHBondContact O-CB 3.48Å; K364-S509 WeakPolarHBondContact CB-O 3.03Å; D507-S509 PolarHBondContact O-N 3.47Å; D507-S509 VanDerWaalsContact O-N 3.13Å; D507-S509 PolarHBondContact OD1-N 3.25Å; D507-S509 PolarHBondContact OD1-OG 2.98Å; S509-S511 PolarHBondContact O-N 3.18Å; S509-S511 VanDerWaalsContact O-N 3.13Å; S509-S511 WeakPolarHBondContact OG-CB 3.36Å; S509-S511 PolarHBondContact OG-OG 2.96Å; S509-S511 VanDerWaalsContact OG-OG 3.07Å
510E98Very high97.6Very high0 Ų058.4 Ų58.40%033%0.326CS..  trans4942.1179.8-60.3167.711700112.5K364 W371 E372 K464 F466 F502 L504 D507 P508K364-E510 HydrophobicContact CB-CB 4.42Å; K364-E510 HydrophobicContact CD-CB 4.11Å; K364-E510 WeakPolarHBondContact CD-O 3.3Å; K364-E510 PolarHBondContact NZ-O 3.33Å; W371-E510 HydrophobicContact CE3-CB 3.74Å; W371-E510 VanDerWaalsContact CE3-CD 3.48Å; W371-E510 HydrophobicContact CE3-CG 4.2Å; W371-E510 HydrophobicContact CZ3-CB 3.71Å; W371-E510 HydrophobicContact CZ3-CG 4.4Å; E372-E510 WeakPolarHBondContact CB-OE2 3.3Å; E372-E510 HydrophobicContact CG-CG 4.18Å; E372-E510 WeakPolarHBondContact CG-OE2 3.47Å; E372-E510 PolarHBondContact N-OE2 3.18Å; K464-E510 WeakPolarHBondContact CE-OE1 3.28Å; K464-E510 IonicContact NZ-OE1 2.82Å; K464-E510 PolarHBondContact NZ-OE1 3.15Å; F466-E510 WeakPolarHBondContact CE2-OE1 3.32Å; F502-E510 HydrophobicContact CD1-CB 4.09Å; F502-E510 HydrophobicContact CE1-CB 4.14Å; F502-E510 WeakPolarHBondContact CE1-O 3.44Å; F502-E510 HydrophobicContact CG-CB 4.42Å; F502-E510 HydrophobicContact CG-CG 4.47Å; L504-E510 HydrophobicContact CD2-CG 3.53Å; D507-E510 PolarHBondContact O-N 2.9Å; D507-E510 VanDerWaalsContact O-N 3.14Å; D507-E510 PolarHBondContact OD1-N 3.07Å; P508-E510 VanDerWaalsContact C-N 3.32Å
511S96.2Very high97.5Very high68 Ų6858.1 Ų58.148%0.47633%0.33SS..  trans-95.5-25.5-17466.20000112.4D507 S509D507-S511 PolarHBondContact OD1-OG 2.9Å; D507-S511 VanDerWaalsContact OD1-OG 3.12Å; D507-S511 PolarHBondContact OD2-N 3.03Å; D507-S511 PolarHBondContact OD2-OG 3.34Å; S509-S511 PolarHBondContact O-N 3.18Å; S509-S511 VanDerWaalsContact O-N 3.13Å; S509-S511 WeakPolarHBondContact OG-CB 3.36Å; S509-S511 PolarHBondContact OG-OG 2.96Å; S509-S511 VanDerWaalsContact OG-OG 3.07Å
512R96.4Very high97.5Very high192 Ų19258.5 Ų58.573%0.72533%0.331SS*.SBendtrans-12794.1-173.7-64.3-179.6-172.9-159.41.1110.2D507D507-R512 PolarHBondContact OD2-N 2.98Å
513P97.6Very high97.5Very high60 Ų6066 Ų6639%0.3936%0.361SS..  trans-65.8145.1174.628.7-34000110.7L500 L501 F502L500-P513 HydrophobicContact CD1-CB 3.34Å; L500-P513 HydrophobicContact CD1-CG 3.98Å; L500-P513 HydrophobicContact CG-CB 3.91Å; L501-P513 CarbonylContact O-C 3.52Å; L501-P513 WeakPolarHBondContact O-CA 3.39Å; F502-P513 HydrophobicContact CD1-CB 4.48Å; F502-P513 HydrophobicContact CE1-CB 3.84Å; F502-P513 HydrophobicContact CZ-CB 3.9Å
514L98.4Very high97.4Very high35 Ų3569.4 Ų69.418%0.18339%0.385CS..BIsolated β-bridgetrans-86154.7175-60.2173.8000110.4W463 L501 D503 E519 F522W463-L514 HydrophobicContact CE3-CD1 4.1Å; W463-L514 HydrophobicContact CH2-CD1 4.47Å; W463-L514 HydrophobicContact CZ3-CD1 3.44Å; W463-L514 VanDerWaalsContact CZ3-CD1 3.44Å; L501-L514 HydrophobicContact CB-CB 4.45Å; L501-L514 HydrophobicContact CG-CD1 4.5Å; L501-L514 PolarHBondContact O-N 3.13Å; D503-L514 HydrophobicContact CB-CD1 4.05Å; L514-E519 HydrophobicContact CB-CB 4.25Å; L514-E519 HydrophobicContact CD1-CB 4.34Å; L514-F522 WeakPolarHBondContact O-CE2 3.12Å
515T97.8Very high97.5Very high59 Ų5969.3 Ų69.336%0.36238%0.384SS..  trans-137.5169.9178.966.50000109.2D517 T518 E519T515-D517 PolarHBondContact O-N 2.96Å; T515-D517 VanDerWaalsContact O-N 3.11Å; T515-D517 PolarHBondContact OG1-N 3.37Å; T515-T518 PolarHBondContact N-OG1 2.94Å; T515-T518 PolarHBondContact O-N 2.88Å; T515-T518 PolarHBondContact O-OG1 3.33Å; T515-T518 PolarHBondContact OG1-N 2.87Å; T515-T518 PolarHBondContact OG1-OG1 3.35Å; T515-E519 PolarHBondContact O-N 2.88Å
516A97Very high97.5Very high43 Ų4367.4 Ų67.436%0.35537%0.37SS..THydrogen-bonded Turntrans-58.7-22.5173.600000113.6F522 Y523A516-F522 HydrophobicContact CB-CB 4.45Å; A516-F522 HydrophobicContact CB-CD1 4.22Å; A516-F522 HydrophobicContact CB-CG 4.47Å; A516-Y523 HydrophobicContact CB-CD2 4.44Å; A516-Y523 HydrophobicContact CB-CE2 3.67Å
517D97Very high97.6Very high159 Ų15963.2 Ų63.285%0.8536%0.362SS*.THydrogen-bonded Turntrans-80.9-28176.7-57.9-39.9000112.7T515T515-D517 PolarHBondContact O-N 2.96Å; T515-D517 VanDerWaalsContact O-N 3.11Å; T515-D517 PolarHBondContact OG1-N 3.37Å
518T97Very high97.6Very high87 Ų8763.3 Ų63.353%0.53437%0.366SS..THydrogen-bonded Turntrans-103.1-18.2-174.852.50000113.4T515T515-T518 PolarHBondContact N-OG1 2.94Å; T515-T518 PolarHBondContact O-N 2.88Å; T515-T518 PolarHBondContact O-OG1 3.33Å; T515-T518 PolarHBondContact OG1-N 2.87Å; T515-T518 PolarHBondContact OG1-OG1 3.35Å
519E97.3Very high97.7Very high32 Ų3261.6 Ų61.615%0.1536%0.355CS..  trans-133.8106.6176.9178.246.4-106.500110.6W463 L514 T515 A521 F522 I525W463-E519 HydrophobicContact CH2-CG 4.37Å; W463-E519 WeakPolarHBondContact CH2-OE2 3.33Å; W463-E519 HydrophobicContact CZ3-CG 4.47Å; L514-E519 HydrophobicContact CB-CB 4.25Å; L514-E519 HydrophobicContact CD1-CB 4.34Å; T515-E519 PolarHBondContact O-N 2.88Å; E519-A521 PolarHBondContact O-N 3.4Å; E519-A521 WeakPolarHBondContact OE1-CB 3.48Å; E519-A521 PolarHBondContact OE1-N 2.98Å; E519-F522 HydrophobicContact CB-CB 4.33Å; E519-F522 HydrophobicContact CG-CB 4.46Å; E519-F522 WeakPolarHBondContact O-CB 3.35Å; E519-F522 PolarHBondContact O-N 3.2Å; E519-I525 HydrophobicContact CG-CD1 3.89Å
520P96.9Very high97.8Very high130 Ų13065.6 Ų65.684%0.84437%0.368SS*.THydrogen-bonded Turntrans-58.3-29.1179.6-26.335.3000114.4F522P520-F522 VanDerWaalsContact C-N 3.31Å
521A97.1Very high97.8Very high35 Ų3571.8 Ų71.829%0.28940%0.397SS..THydrogen-bonded Turntrans-87.99.6177.300000113.5E519 Y523 S524 I525E519-A521 PolarHBondContact O-N 3.4Å; E519-A521 WeakPolarHBondContact OE1-CB 3.48Å; E519-A521 PolarHBondContact OE1-N 2.98Å; A521-Y523 PolarHBondContact O-N 3.37Å; A521-S524 PolarHBondContact O-N 3.15Å; A521-S524 PolarHBondContact O-OG 3.25Å; A521-I525 HydrophobicContact CB-CD1 3.82Å; A521-I525 HydrophobicContact CB-CG1 4.07Å; A521-I525 WeakPolarHBondContact O-CD1 3.4Å; A521-I525 VanDerWaalsContact O-CG1 3.27Å; A521-I525 WeakPolarHBondContact O-CG1 3.36Å; A521-I525 PolarHBondContact O-N 3.01Å
522F98.6Very high97.9Very high9 Ų969.2 Ų69.24%0.03938%0.379CS..Hα-helixtrans-48.9-52-171.9-178.4-94.8000113.4P498 L501 L514 A516 E519 P520 L526P498-F522 HydrophobicContact CB-CE1 4.1Å; P498-F522 HydrophobicContact CB-CZ 4.37Å; P498-F522 HydrophobicContact CG-CE1 3.85Å; P498-F522 HydrophobicContact CG-CZ 4.09Å; L501-F522 HydrophobicContact CB-CD2 4.3Å; L501-F522 HydrophobicContact CB-CE2 3.75Å; L501-F522 HydrophobicContact CD2-CD2 3.67Å; L501-F522 HydrophobicContact CD2-CE2 3.98Å; L501-F522 HydrophobicContact CD2-CG 4.49Å; L514-F522 WeakPolarHBondContact O-CE2 3.12Å; A516-F522 HydrophobicContact CB-CB 4.45Å; A516-F522 HydrophobicContact CB-CD1 4.22Å; A516-F522 HydrophobicContact CB-CG 4.47Å; E519-F522 HydrophobicContact CB-CB 4.33Å; E519-F522 HydrophobicContact CG-CB 4.46Å; E519-F522 WeakPolarHBondContact O-CB 3.35Å; E519-F522 PolarHBondContact O-N 3.2Å; P520-F522 VanDerWaalsContact C-N 3.31Å; F522-L526 HydrophobicContact CD1-CD1 3.92Å; F522-L526 HydrophobicContact CE1-CD1 3.37Å; F522-L526 HydrophobicContact CE2-CD1 4.24Å; F522-L526 HydrophobicContact CZ-CD1 3.56Å; F522-L526 WeakPolarHBondContact O-CG 3.3Å; F522-L526 PolarHBondContact O-N 2.86Å; F522-L526 VanDerWaalsContact O-N 3.13Å
523Y98.4Very high98Very high159 Ų15960.5 Ų60.562%0.62435%0.348SS*.Hα-helixtrans-72.4-32.1-178.6-67.6-67.2000113.7A516 A521 A527A516-Y523 HydrophobicContact CB-CD2 4.44Å; A516-Y523 HydrophobicContact CB-CE2 3.67Å; A521-Y523 PolarHBondContact O-N 3.37Å; Y523-A527 VanDerWaalsContact O-CB 3.29Å; Y523-A527 WeakPolarHBondContact O-CB 3.48Å; Y523-A527 PolarHBondContact O-N 3.11Å
524S98.1Very high98.1Very high78 Ų7861.8 Ų61.855%0.54535%0.348SS..Hα-helixtrans-73.4-36.7178.2580000111.7A521 A527 A528A521-S524 PolarHBondContact O-N 3.15Å; A521-S524 PolarHBondContact O-OG 3.25Å; S524-A527 PolarHBondContact O-N 2.95Å; S524-A528 PolarHBondContact O-N 2.87Å
525I98.5Very high98.1Very high6 Ų664.5 Ų64.53%0.03137%0.366CS..Hα-helixtrans-59.6-53.2171.9-66.2161.7000109.8W454 W463 L501 E519 A521 A527 A528 M529W454-I525 HydrophobicContact CE3-CG2 4.06Å; W454-I525 HydrophobicContact CZ3-CB 4.3Å; W454-I525 HydrophobicContact CZ3-CG1 4.18Å; W454-I525 HydrophobicContact CZ3-CG2 4.1Å; W463-I525 HydrophobicContact CB-CG2 4.04Å; W463-I525 HydrophobicContact CD2-CD1 3.96Å; W463-I525 HydrophobicContact CD2-CG2 4.23Å; W463-I525 HydrophobicContact CE3-CD1 4.11Å; W463-I525 HydrophobicContact CG-CG2 3.9Å; W463-I525 HydrophobicContact CH2-CD1 3.93Å; W463-I525 HydrophobicContact CZ2-CD1 3.8Å; W463-I525 HydrophobicContact CZ3-CD1 4.06Å; L501-I525 HydrophobicContact CD1-CG2 3.92Å; L501-I525 HydrophobicContact CD2-CB 4.35Å; L501-I525 HydrophobicContact CD2-CD1 4.31Å; L501-I525 HydrophobicContact CD2-CG2 3.99Å; E519-I525 HydrophobicContact CG-CD1 3.89Å; A521-I525 HydrophobicContact CB-CD1 3.82Å; A521-I525 HydrophobicContact CB-CG1 4.07Å; A521-I525 WeakPolarHBondContact O-CD1 3.4Å; A521-I525 VanDerWaalsContact O-CG1 3.27Å; A521-I525 WeakPolarHBondContact O-CG1 3.36Å; A521-I525 PolarHBondContact O-N 3.01Å; I525-A527 VanDerWaalsContact C-N 3.28Å; I525-A527 PolarHBondContact O-N 3.28Å; I525-A528 PolarHBondContact O-N 3.17Å; I525-M529 HydrophobicContact CG2-SD 3.68Å; I525-M529 WeakPolarHBondContact O-CG 3.21Å; I525-M529 PolarHBondContact O-N 2.89Å
526L98.7Very high98.1Very high19 Ų1962.1 Ų62.110%0.09935%0.351CS..Hα-helixtrans-62.4-34.8179.6-69.8178.8000112.8A465 P498 P499 L501 F522 K530A465-L526 HydrophobicContact CB-CD2 3.82Å; P498-L526 HydrophobicContact CB-CD1 3.87Å; P499-L526 HydrophobicContact CB-CD2 4.03Å; P499-L526 HydrophobicContact CG-CD2 4.37Å; L501-L526 HydrophobicContact CB-CD2 4.45Å; L501-L526 HydrophobicContact CD1-CD2 4.2Å; F522-L526 HydrophobicContact CD1-CD1 3.92Å; F522-L526 HydrophobicContact CE1-CD1 3.37Å; F522-L526 HydrophobicContact CE2-CD1 4.24Å; F522-L526 HydrophobicContact CZ-CD1 3.56Å; F522-L526 WeakPolarHBondContact O-CG 3.3Å; F522-L526 PolarHBondContact O-N 2.86Å; F522-L526 VanDerWaalsContact O-N 3.13Å; L526-K530 VanDerWaalsContact O-CB 3.28Å; L526-K530 WeakPolarHBondContact O-CB 3.12Å; L526-K530 PolarHBondContact O-N 3.04Å
527A98.6Very high98.1Very high58 Ų5865 Ų6548%0.47936%0.357SS..Hα-helixtrans-65.2-44.6175.500000112.3Y523 S524 I525 K530 Q531Y523-A527 VanDerWaalsContact O-CB 3.29Å; Y523-A527 WeakPolarHBondContact O-CB 3.48Å; Y523-A527 PolarHBondContact O-N 3.11Å; S524-A527 PolarHBondContact O-N 2.95Å; I525-A527 VanDerWaalsContact C-N 3.28Å; I525-A527 PolarHBondContact O-N 3.28Å; A527-K530 PolarHBondContact O-N 3.45Å; A527-Q531 PolarHBondContact O-N 2.88Å
528A98.5Very high98.1Very high25 Ų2565.7 Ų65.721%0.20735%0.352CS..Hα-helixtrans-62.1-45.1176.300000111.5W454 S524 I525 K530 Q531 A532W454-A528 HydrophobicContact CH2-CB 3.89Å; W454-A528 HydrophobicContact CZ2-CB 4.13Å; W454-A528 HydrophobicContact CZ3-CB 4.14Å; S524-A528 PolarHBondContact O-N 2.87Å; I525-A528 PolarHBondContact O-N 3.17Å; A528-K530 PolarHBondContact O-N 3.11Å; A528-Q531 PolarHBondContact O-N 3.46Å; A528-A532 PolarHBondContact O-N 3.33Å
529M98.8Very high98.1Very high1 Ų163.1 Ų63.11%0.00534%0.338CS..Hα-helixtrans-62.5-42.7176.8-67.4172.396.400112.1F440 V452 W454 W463 A465 L501 I525 Q531 A532 V533F440-M529 HydrophobicContact CE1-CG 4.34Å; V452-M529 HydrophobicContact CG1-CB 3.86Å; V452-M529 HydrophobicContact CG1-CE 3.73Å; V452-M529 HydrophobicContact CG1-CG 4.38Å; V452-M529 WeakPolarHBondContact O-CE 3.14Å; W454-M529 HydrophobicContact CB-CE 4.11Å; W454-M529 HydrophobicContact CB-CG 3.96Å; W454-M529 HydrophobicContact CB-SD 4.44Å; W454-M529 HydrophobicContact CE3-CG 4.25Å; W454-M529 HydrophobicContact CG-CG 4.47Å; W463-M529 HydrophobicContact CB-CE 4.26Å; W463-M529 HydrophobicContact CB-SD 4.29Å; A465-M529 HydrophobicContact CB-CE 3.57Å; A465-M529 HydrophobicContact CB-SD 3.85Å; L501-M529 HydrophobicContact CD1-SD 4.06Å; I525-M529 HydrophobicContact CG2-SD 3.68Å; I525-M529 WeakPolarHBondContact O-CG 3.21Å; I525-M529 PolarHBondContact O-N 2.89Å; M529-Q531 PolarHBondContact O-N 3.22Å; M529-A532 PolarHBondContact O-N 3.46Å; M529-V533 WeakPolarHBondContact O-CG2 3.5Å; M529-V533 PolarHBondContact O-N 2.9Å
530K98.6Very high98Very high123 Ų12363 Ų6354%0.53534%0.339SS..Hα-helixtrans-61.2-44.1175.2-177.1179.4177.5179.80111.8L526 A527 A528 A532 V533 E534L526-K530 VanDerWaalsContact O-CB 3.28Å; L526-K530 WeakPolarHBondContact O-CB 3.12Å; L526-K530 PolarHBondContact O-N 3.04Å; A527-K530 PolarHBondContact O-N 3.45Å; A528-K530 PolarHBondContact O-N 3.11Å; K530-A532 PolarHBondContact O-N 3.36Å; K530-V533 PolarHBondContact O-N 3.08Å; K530-E534 WeakPolarHBondContact CE-OE1 3.49Å; K530-E534 WeakPolarHBondContact O-CG 3.44Å; K530-E534 PolarHBondContact O-N 2.93Å
531Q98.6Very high97.9Very high130 Ų13064.5 Ų64.561%0.60733%0.333SS*.Hα-helixtrans-60.9-44.4177-176.8179.3-0.800111.6A527 A528 M529 V533 E534 V535A527-Q531 PolarHBondContact O-N 2.88Å; A528-Q531 PolarHBondContact O-N 3.46Å; M529-Q531 PolarHBondContact O-N 3.22Å; Q531-V533 VanDerWaalsContact C-N 3.32Å; Q531-V533 PolarHBondContact O-N 3.34Å; Q531-E534 PolarHBondContact O-N 2.9Å; Q531-V535 WeakPolarHBondContact O-CG2 3.27Å; Q531-V535 PolarHBondContact O-N 3.33Å
532A98.6Very high97.7Very high14 Ų1469.3 Ų69.312%0.11636%0.361CS..Hα-helixtrans-61.9-40.2176.200000112F440 F442 A528 M529 K530 V535 H536F440-A532 HydrophobicContact CD1-CB 3.52Å; F440-A532 HydrophobicContact CD2-CB 3.87Å; F440-A532 HydrophobicContact CE1-CB 3.37Å; F440-A532 HydrophobicContact CE2-CB 3.74Å; F440-A532 HydrophobicContact CG-CB 3.76Å; F440-A532 HydrophobicContact CZ-CB 3.49Å; F440-A532 VanDerWaalsContact CZ-CB 3.49Å; F442-A532 HydrophobicContact CZ-CB 4.38Å; A528-A532 PolarHBondContact O-N 3.33Å; M529-A532 PolarHBondContact O-N 3.46Å; K530-A532 PolarHBondContact O-N 3.36Å; A532-V535 PolarHBondContact O-N 3.49Å; A532-H536 WeakPolarHBondContact O-CB 3.45Å; A532-H536 PolarHBondContact O-N 3.23Å
533V98.6Very high97.5Very high9 Ų971.3 Ų71.36%0.05537%0.374CS..Hα-helixtrans-61.8-43.8174164.80000111.9F442 L449 V452 Y467 M529 K530 Q531 V535 H536 Q537F442-V533 HydrophobicContact CD1-CG2 4.05Å; F442-V533 HydrophobicContact CE1-CG2 3.83Å; L449-V533 HydrophobicContact CD2-CB 4.25Å; L449-V533 HydrophobicContact CD2-CG1 3.37Å; L449-V533 HydrophobicContact CD2-CG2 3.88Å; V452-V533 HydrophobicContact CB-CG2 4Å; V452-V533 HydrophobicContact CG1-CG2 4.06Å; V452-V533 HydrophobicContact CG2-CG2 4.11Å; Y467-V533 HydrophobicContact CE2-CG2 4.25Å; Y467-V533 WeakPolarHBondContact OH-CG2 3.4Å; M529-V533 WeakPolarHBondContact O-CG2 3.5Å; M529-V533 PolarHBondContact O-N 2.9Å; K530-V533 PolarHBondContact O-N 3.08Å; Q531-V533 VanDerWaalsContact C-N 3.32Å; Q531-V533 PolarHBondContact O-N 3.34Å; V533-V535 VanDerWaalsContact C-N 3.32Å; V533-V535 PolarHBondContact O-N 3.05Å; V533-H536 PolarHBondContact O-N 3.24Å; V533-Q537 HydrophobicContact CG1-CG 4.21Å; V533-Q537 WeakPolarHBondContact O-CB 3.29Å; V533-Q537 VanDerWaalsContact O-CG 3.32Å; V533-Q537 WeakPolarHBondContact O-CG 3.45Å; V533-Q537 PolarHBondContact O-N 3.34Å
534E98.4Very high97.3Very high86 Ų8669.3 Ų69.340%0.40237%0.37SS..Hα-helixtrans-62.5-38.6177.1-72174.9-168.500112.2K530 Q531 K538K530-E534 WeakPolarHBondContact CE-OE1 3.49Å; K530-E534 WeakPolarHBondContact O-CG 3.44Å; K530-E534 PolarHBondContact O-N 2.93Å; Q531-E534 PolarHBondContact O-N 2.9Å; E534-K538 WeakPolarHBondContact O-CD 3.34Å; E534-K538 VanDerWaalsContact O-CG 3.26Å; E534-K538 WeakPolarHBondContact O-CG 3.24Å; E534-K538 PolarHBondContact O-N 3.44Å
535V98.3Very high97.2Very high92 Ų9267.3 Ų67.356%0.55836%0.356SS*.Hα-helixtrans-67.1-47.6174.5173.10000110.7Q531 A532 V533 Q537 K538 S539Q531-V535 WeakPolarHBondContact O-CG2 3.27Å; Q531-V535 PolarHBondContact O-N 3.33Å; A532-V535 PolarHBondContact O-N 3.49Å; V533-V535 VanDerWaalsContact C-N 3.32Å; V533-V535 PolarHBondContact O-N 3.05Å; V535-Q537 PolarHBondContact O-N 2.67Å; V535-K538 PolarHBondContact O-N 3.35Å; V535-S539 PolarHBondContact O-N 2.97Å
536H98.1Very high97.1Very high10 Ų1067.2 Ų67.25%0.04636%0.355CS..Hα-helixtrans-59.4-49.6179173.873.8000111.8Y90 F442 Y444 A532 V533 K538 S539 V540Y90-H536 AromaticContact CD2-CE1 3.66Å; Y90-H536 AromaticContact CE2-CE1 3.83Å; F442-H536 HydrophobicContact CD1-CB 4.17Å; F442-H536 AromaticContact CD1-CD2 3.99Å; F442-H536 AromaticContact CD1-CG 3.99Å; F442-H536 HydrophobicContact CD2-CB 4.18Å; F442-H536 AromaticContact CD2-CE1 3.74Å; F442-H536 AromaticContact CD2-CG 3.6Å; F442-H536 AromaticContact CD2-ND1 3.41Å; F442-H536 WeakPolarHBondContact CD2-ND1 3.38Å; F442-H536 HydrophobicContact CE1-CB 3.66Å; F442-H536 AromaticContact CE1-CG 3.97Å; F442-H536 HydrophobicContact CE2-CB 3.67Å; F442-H536 AromaticContact CE2-CG 3.59Å; F442-H536 AromaticContact CE2-ND1 3.52Å; F442-H536 HydrophobicContact CG-CB 4.41Å; F442-H536 AromaticContact CG-CD2 3.81Å; F442-H536 AromaticContact CG-CG 3.81Å; F442-H536 HydrophobicContact CZ-CB 3.39Å; F442-H536 AromaticContact CZ-CG 3.78Å; Y444-H536 AromaticContact CE2-NE2 3.46Å; Y444-H536 WeakPolarHBondContact CE2-NE2 3.07Å; Y444-H536 AromaticContact CZ-NE2 3.68Å; Y444-H536 PolarHBondContact OH-CD2 2.67Å; Y444-H536 PolarHBondContact OH-NE2 3.2Å; A532-H536 WeakPolarHBondContact O-CB 3.45Å; A532-H536 PolarHBondContact O-N 3.23Å; V533-H536 PolarHBondContact O-N 3.24Å; H536-K538 VanDerWaalsContact C-N 3.26Å; H536-K538 PolarHBondContact O-N 3.46Å; H536-S539 WeakPolarHBondContact O-CA 3.31Å; H536-S539 WeakPolarHBondContact O-CB 3.4Å; H536-S539 PolarHBondContact O-N 3.15Å; H536-S539 PolarHBondContact O-OG 3.49Å; H536-V540 PolarHBondContact O-N 3.21Å
537Q97.4Very high97Very high103 Ų10366.3 Ų66.348%0.48135%0.351SS..Hα-helixtrans-60.4-34.7-179.9-74.5179.1-21.900112.5V533 V535 S539 V540V533-Q537 HydrophobicContact CG1-CG 4.21Å; V533-Q537 WeakPolarHBondContact O-CB 3.29Å; V533-Q537 VanDerWaalsContact O-CG 3.32Å; V533-Q537 WeakPolarHBondContact O-CG 3.45Å; V533-Q537 PolarHBondContact O-N 3.34Å; V535-Q537 PolarHBondContact O-N 2.67Å; Q537-S539 VanDerWaalsContact C-N 3.26Å; Q537-S539 PolarHBondContact O-N 2.94Å; Q537-V540 PolarHBondContact O-N 2.81Å
538K97.1Very high96.8Very high173 Ų17365.2 Ų65.275%0.75234%0.34SS*.Hα-helixtrans-65.1-28.3173-72.6168.4-173.8169.60112.9E534 V535 H536E534-K538 WeakPolarHBondContact O-CD 3.34Å; E534-K538 VanDerWaalsContact O-CG 3.26Å; E534-K538 WeakPolarHBondContact O-CG 3.24Å; E534-K538 PolarHBondContact O-N 3.44Å; V535-K538 PolarHBondContact O-N 3.35Å; H536-K538 VanDerWaalsContact C-N 3.26Å; H536-K538 PolarHBondContact O-N 3.46Å
539S96.7Very high96.6Very high34 Ų3466.4 Ų66.424%0.23835%0.349CS..Hα-helixtrans-77-21.5175.482.70000113.2R93 V535 H536 Q537 K541R93-S539 PolarHBondContact NH1-O 3.48Å; R93-S539 VanDerWaalsContact NH1-O 3.11Å; R93-S539 PolarHBondContact NH1-OG 3.24Å; R93-S539 PolarHBondContact NH2-OG 2.97Å; V535-S539 PolarHBondContact O-N 2.97Å; H536-S539 WeakPolarHBondContact O-CA 3.31Å; H536-S539 WeakPolarHBondContact O-CB 3.4Å; H536-S539 PolarHBondContact O-N 3.15Å; H536-S539 PolarHBondContact O-OG 3.49Å; Q537-S539 VanDerWaalsContact C-N 3.26Å; Q537-S539 PolarHBondContact O-N 2.94Å; S539-K541 PolarHBondContact O-N 2.77Å
540V96.3Very high96.3Very high28 Ų2868.9 Ų68.917%0.1737%0.37CS..  trans-81.3101.7-178.3179.10000109.3I92 H536 Q537I92-V540 HydrophobicContact CB-CG1 4.45Å; I92-V540 HydrophobicContact CG1-CG1 3.82Å; I92-V540 HydrophobicContact CG2-CG1 3.86Å; I92-V540 HydrophobicContact CG2-CG2 4.14Å; H536-V540 PolarHBondContact O-N 3.21Å; Q537-V540 PolarHBondContact O-N 2.81Å
541K94.4Very high96.2Very high163 Ų16364.3 Ų64.371%0.70935%0.35SS*.  trans-76.1138.1176-62-179.9-175.91740110.1S539 V543S539-K541 PolarHBondContact O-N 2.77Å; K541-V543 PolarHBondContact O-N 2.8Å
542P92.3Very high96Very high135 Ų13559 Ų5988%0.87733%0.326SS*.  trans-57.1131.7174.4-24.934.1000111.8
543V94.5Very high95.8Very high51 Ų5163.7 Ų63.731%0.30935%0.347SS..  trans-132.8155.1175.9-68.20000109.4I92 K541 S545I92-V543 VanDerWaalsContact O-CG2 3.23Å; I92-V543 WeakPolarHBondContact O-CG2 3.48Å; K541-V543 PolarHBondContact O-N 2.8Å; V543-S545 PolarHBondContact O-N 3.37Å
544E94.2Very high95.6Very high117 Ų11767.5 Ų67.555%0.54736%0.36SS..  trans-63.7126.3175.7-179.3173.6-155.400110.7G95 Q546 H551G95-E544 WeakPolarHBondContact CA-O 3.35Å; E544-Q546 PolarHBondContact O-N 3.12Å; E544-H551 IonicContact OE1-CE1 2.84Å; E544-H551 PolarHBondContact OE1-CE1 2.95Å; E544-H551 VanDerWaalsContact OE1-CE1 3.23Å; E544-H551 IonicContact OE1-NE2 3.35Å
545S95.8Very high95.5Very high36 Ų3665.2 Ų65.225%0.25235%0.349SS..  trans-72.4117.9176.8-178.20000110.6A97 V543 L547 S548 H551A97-S545 PolarHBondContact O-OG 2.94Å; V543-S545 PolarHBondContact O-N 3.37Å; S545-L547 PolarHBondContact O-N 3.26Å; S545-L547 PolarHBondContact OG-N 3.27Å; S545-S548 PolarHBondContact O-N 3.08Å; S545-H551 PolarHBondContact O-ND1 3.35Å
546Q97.3Very high95.3Very high4 Ų463.8 Ų63.82%0.01934%0.342CS..THydrogen-bonded Turntrans-78.5-6.2173.7-59.6-59.6-60.700112G95 F105 G113 L115 E544 H551G95-Q546 WeakPolarHBondContact O-CB 3.44Å; G95-Q546 PolarHBondContact O-N 3.05Å; F105-Q546 VanDerWaalsContact CE1-O 3.23Å; F105-Q546 WeakPolarHBondContact CE1-O 3.46Å; F105-Q546 HydrophobicContact CZ-CB 4.41Å; G113-Q546 WeakPolarHBondContact O-CB 3.45Å; G113-Q546 VanDerWaalsContact O-CG 3.26Å; G113-Q546 WeakPolarHBondContact O-CG 3.43Å; L115-Q546 HydrophobicContact CD1-CG 4.46Å; L115-Q546 HydrophobicContact CD2-CG 4.3Å; L115-Q546 HydrophobicContact CG-CG 4.1Å; E544-Q546 PolarHBondContact O-N 3.12Å; Q546-H551 VanDerWaalsContact O-CB 3.22Å; Q546-H551 WeakPolarHBondContact O-CB 3.23Å
547L95.8Very high95.2Very high0 Ų071 Ų710%037%0.368CS..THydrogen-bonded Turntrans-109.827.3173.4-68.3172.2000112G103 F105 S545 I552G103-L547 WeakPolarHBondContact O-CD1 3.4Å; F105-L547 HydrophobicContact CD1-CD2 3.9Å; F105-L547 HydrophobicContact CE1-CD2 3.61Å; F105-L547 HydrophobicContact CE2-CD2 4.34Å; F105-L547 HydrophobicContact CG-CD2 4.36Å; F105-L547 HydrophobicContact CZ-CD2 3.84Å; F105-L547 HydrophobicContact CZ-CG 4.46Å; S545-L547 PolarHBondContact O-N 3.26Å; S545-L547 PolarHBondContact OG-N 3.27Å; L547-I552 HydrophobicContact CB-CG2 4.36Å; L547-I552 HydrophobicContact CD2-CG2 3.89Å
548S94.9Very high95.2Very high36 Ų3666 Ų6625%0.25235%0.346SS..SBendtrans-74.2162.3171.387.40000111.3S545 A550 H551 I552S545-S548 PolarHBondContact O-N 3.08Å; S548-A550 PolarHBondContact O-N 3.49Å; S548-A550 PolarHBondContact OG-N 2.95Å; S548-H551 PolarHBondContact O-N 2.88Å; S548-H551 PolarHBondContact OG-N 2.88Å; S548-H551 PolarHBondContact OG-ND1 2.89Å; S548-I552 WeakPolarHBondContact O-CG1 3.32Å; S548-I552 PolarHBondContact O-N 3.41Å
549A93Very high95.1Very high49 Ų4958 Ų5841%0.40531%0.311SS..Hα-helixtrans-55.2-41.2178.900000112L100 H551 M553L100-A549 HydrophobicContact CD1-CB 3.87Å; L100-A549 VanDerWaalsContact CD1-N 3.28Å; A549-H551 VanDerWaalsContact C-N 3.28Å; A549-H551 PolarHBondContact O-N 3.34Å; A549-M553 WeakPolarHBondContact O-CB 3.37Å; A549-M553 WeakPolarHBondContact O-CG 3.36Å; A549-M553 PolarHBondContact O-N 2.86Å
550A94Very high95Very high53 Ų5356.7 Ų56.744%0.43830%0.301SS..Hα-helixtrans-67.1-27.9179.300000113.4S548 K555S548-A550 PolarHBondContact O-N 3.49Å; S548-A550 PolarHBondContact OG-N 2.95Å; A550-K555 WeakPolarHBondContact O-CE 3.17Å; A550-K555 PolarHBondContact O-NZ 2.8Å
551H96.3Very high94.9Very high28 Ų2857 Ų5713%0.1330%0.304CS..Hα-helixtrans-87.7-32.4-179.2-70.8119.4000112.9A110 S111 G112 E544 S545 Q546 S548 A549A110-H551 WeakPolarHBondContact CB-O 3.27Å; S111-H551 PolarHBondContact N-O 2.94Å; S111-H551 PolarHBondContact OG-CD2 2.75Å; G112-H551 PolarHBondContact N-O 3.48Å; G112-H551 VanDerWaalsContact N-O 3.1Å; E544-H551 IonicContact OE1-CE1 2.84Å; E544-H551 PolarHBondContact OE1-CE1 2.95Å; E544-H551 VanDerWaalsContact OE1-CE1 3.23Å; E544-H551 IonicContact OE1-NE2 3.35Å; S545-H551 PolarHBondContact O-ND1 3.35Å; Q546-H551 VanDerWaalsContact O-CB 3.22Å; Q546-H551 WeakPolarHBondContact O-CB 3.23Å; S548-H551 PolarHBondContact O-N 2.88Å; S548-H551 PolarHBondContact OG-N 2.88Å; S548-H551 PolarHBondContact OG-ND1 2.89Å; A549-H551 VanDerWaalsContact C-N 3.28Å; A549-H551 PolarHBondContact O-N 3.34Å
552I94.9Very high94.7Very high18 Ų1851.3 Ų51.39%0.09229%0.285CS..Hα-helixtrans-91.8-16.8-176.269.6-178.2000114.5L100 P102 F105 F107 L547 S548L100-I552 HydrophobicContact CD1-CD1 3.81Å; P102-I552 HydrophobicContact CB-CD1 4.14Å; P102-I552 HydrophobicContact CG-CD1 4.01Å; F105-I552 HydrophobicContact CD1-CG2 4.32Å; F105-I552 HydrophobicContact CE1-CG2 4.33Å; F107-I552 WeakPolarHBondContact CD2-O 3.42Å; L547-I552 HydrophobicContact CB-CG2 4.36Å; L547-I552 HydrophobicContact CD2-CG2 3.89Å; S548-I552 WeakPolarHBondContact O-CG1 3.32Å; S548-I552 PolarHBondContact O-N 3.41Å
553M93.1Very high94.5Very high113 Ų11346.7 Ų46.756%0.55726%0.255SS*.SBendtrans-68.6145179.1-80.1-172.6-51.100111.6A549 K555A549-M553 WeakPolarHBondContact O-CB 3.37Å; A549-M553 WeakPolarHBondContact O-CG 3.36Å; A549-M553 PolarHBondContact O-N 2.86Å; M553-K555 PolarHBondContact O-N 3.49Å
554W94.8Very high94Very high89 Ų8947.3 Ų47.334%0.33726%0.259SS..  trans-62.8126.6172.6-179.273.1000111.2F107 L239 P556F107-W554 HydrophobicContact CD1-CB 3.93Å; F107-W554 AromaticContact CD1-CD1 3.88Å; F107-W554 HydrophobicContact CD1-CG 4.19Å; F107-W554 HydrophobicContact CD2-CB 4Å; F107-W554 HydrophobicContact CE1-CB 4.09Å; F107-W554 HydrophobicContact CE1-CG 4.47Å; F107-W554 HydrophobicContact CE2-CB 4.16Å; F107-W554 HydrophobicContact CG-CB 3.89Å; F107-W554 HydrophobicContact CG-CG 4.47Å; F107-W554 HydrophobicContact CZ-CB 4.2Å; L239-W554 HydrophobicContact CD1-CZ2 4.11Å; W554-P556 HydrophobicContact CE3-CG 4.1Å; W554-P556 HydrophobicContact CH2-CB 4Å; W554-P556 HydrophobicContact CH2-CG 3.74Å; W554-P556 HydrophobicContact CZ2-CB 4.29Å; W554-P556 HydrophobicContact CZ2-CG 4.34Å; W554-P556 HydrophobicContact CZ3-CB 4.38Å; W554-P556 HydrophobicContact CZ3-CG 3.61Å
555K96.4Very high93.3Very high38 Ų3847.5 Ų47.517%0.16526%0.259CS..  trans-117110.7179-69.4174.2176.6-176.90109.6A109 S111 A550 M553 W557 L558A109-K555 WeakPolarHBondContact CB-O 3.34Å; A109-K555 WeakPolarHBondContact O-CB 3.38Å; A109-K555 PolarHBondContact O-N 2.82Å; S111-K555 PolarHBondContact OG-NZ 3.3Å; A550-K555 WeakPolarHBondContact O-CE 3.17Å; A550-K555 PolarHBondContact O-NZ 2.8Å; M553-K555 PolarHBondContact O-N 3.49Å; K555-W557 HydrophobicContact CB-CD2 4.2Å; K555-W557 HydrophobicContact CB-CH2 4.21Å; K555-W557 HydrophobicContact CB-CZ2 3.87Å; K555-W557 HydrophobicContact CD-CH2 4.47Å; K555-W557 HydrophobicContact CD-CZ2 3.72Å; K555-W557 HydrophobicContact CG-CH2 4.04Å; K555-W557 HydrophobicContact CG-CZ2 3.72Å; K555-W557 PolarHBondContact O-N 3.46Å; K555-W557 VanDerWaalsContact O-N 3.12Å; K555-L558 HydrophobicContact CB-CB 4.21Å; K555-L558 HydrophobicContact CB-CD1 3.89Å; K555-L558 HydrophobicContact CB-CG 3.87Å; K555-L558 HydrophobicContact CD-CD1 3.61Å; K555-L558 HydrophobicContact CD-CG 4.32Å; K555-L558 HydrophobicContact CG-CD1 4.35Å; K555-L558 PolarHBondContact O-N 3.17Å
556P94.3Very high92.5Very high62 Ų6252.2 Ų52.240%0.40329%0.286SS..G310 helixtrans-54.8-35.9-175.1-24.729000114.7W554 L558 Q559W554-P556 HydrophobicContact CE3-CG 4.1Å; W554-P556 HydrophobicContact CH2-CB 4Å; W554-P556 HydrophobicContact CH2-CG 3.74Å; W554-P556 HydrophobicContact CZ2-CB 4.29Å; W554-P556 HydrophobicContact CZ2-CG 4.34Å; W554-P556 HydrophobicContact CZ3-CB 4.38Å; W554-P556 HydrophobicContact CZ3-CG 3.61Å; P556-L558 VanDerWaalsContact C-N 3.26Å; P556-L558 PolarHBondContact O-N 2.92Å; P556-Q559 WeakPolarHBondContact O-CB 3.22Å; P556-Q559 PolarHBondContact O-N 2.95Å
557W95.3Very high91.7Very high160 Ų16057.6 Ų57.661%0.60631%0.311SS*.G310 helixtrans-75.5-10.9-179.360.688.9000114.1S147 K555S147-W557 PolarHBondContact N-O 3.04Å; K555-W557 HydrophobicContact CB-CD2 4.2Å; K555-W557 HydrophobicContact CB-CH2 4.21Å; K555-W557 HydrophobicContact CB-CZ2 3.87Å; K555-W557 HydrophobicContact CD-CH2 4.47Å; K555-W557 HydrophobicContact CD-CZ2 3.72Å; K555-W557 HydrophobicContact CG-CH2 4.04Å; K555-W557 HydrophobicContact CG-CZ2 3.72Å; K555-W557 PolarHBondContact O-N 3.46Å; K555-W557 VanDerWaalsContact O-N 3.12Å
558L97.2Very high91.1Very high0 Ų061.1 Ų61.10%033%0.33CS..G310 helixtrans-95.6-4.5173.9-61.1-173.4000112.7A109 N143 E145 K555 P556 P560A109-L558 HydrophobicContact CB-CB 4.11Å; N143-L558 HydrophobicContact CB-CD2 4.33Å; N143-L558 PolarHBondContact ND2-O 3.21Å; E145-L558 WeakPolarHBondContact O-CD2 3.43Å; K555-L558 HydrophobicContact CB-CB 4.21Å; K555-L558 HydrophobicContact CB-CD1 3.89Å; K555-L558 HydrophobicContact CB-CG 3.87Å; K555-L558 HydrophobicContact CD-CD1 3.61Å; K555-L558 HydrophobicContact CD-CG 4.32Å; K555-L558 HydrophobicContact CG-CD1 4.35Å; K555-L558 PolarHBondContact O-N 3.17Å; P556-L558 VanDerWaalsContact C-N 3.26Å; P556-L558 PolarHBondContact O-N 2.92Å; L558-P560 WeakPolarHBondContact O-CD 3.49Å
559Q96.4Very high90.7Very high4 Ų459.5 Ų59.52%0.01932%0.318CS..  trans-70112.1-169.2177.963.760.500111.2A109 L239 P556 C561 F565A109-Q559 HydrophobicContact CB-CB 3.92Å; L239-Q559 HydrophobicContact CD2-CG 4Å; L239-Q559 PolarHBondContact O-NE2 3.48Å; P556-Q559 WeakPolarHBondContact O-CB 3.22Å; P556-Q559 PolarHBondContact O-N 2.95Å; Q559-C561 PolarHBondContact O-N 2.71Å; Q559-F565 HydrophobicContact CB-CE1 4.16Å; Q559-F565 HydrophobicContact CB-CZ 3.92Å; Q559-F565 HydrophobicContact CG-CE1 3.8Å; Q559-F565 HydrophobicContact CG-CZ 3.99Å
560P94.3Very high90.6Very high6 Ų661.5 Ų61.54%0.03932%0.319CS..  trans-63.4136.5170.627.5-36.6000110.3N108 L142 I242 F244 I249 Q252 L558N108-P560 HydrophobicContact CB-CG 4.02Å; L142-P560 HydrophobicContact CD2-CB 4.22Å; L142-P560 HydrophobicContact CD2-CG 3.8Å; I242-P560 HydrophobicContact CD1-CB 4.07Å; I242-P560 HydrophobicContact CD1-CG 3.45Å; I242-P560 VanDerWaalsContact CD1-CG 3.45Å; F244-P560 HydrophobicContact CZ-CB 4.28Å; I249-P560 HydrophobicContact CD1-CB 3.87Å; Q252-P560 PolarHBondContact NE2-O 2.93Å; L558-P560 WeakPolarHBondContact O-CD 3.49Å
561C93.5Very high90.5Very high35 Ų3560.4 Ų60.424%0.23631%0.308CS..  trans-148.8117.8-175.2-168.90000108.9Q559 S563 C569Q559-C561 PolarHBondContact O-N 2.71Å; C561-S563 VanDerWaalsContact C-N 3.31Å; C561-S563 PolarHBondContact O-N 3.49Å; C561-C569 HydrophobicContact CB-CB 3.86Å; C561-C569 WeakPolarHBondContact CB-SG 3.37Å; C561-C569 WeakPolarHBondContact SG-CA 3.37Å; C561-C569 WeakPolarHBondContact SG-CB 3.28Å; C561-C569 CovalentContact SG-SG 2.03Å; C561-C569 PolarHBondContact SG-SG 3.41Å
562C91.4Very high90Very high44 Ų4465.8 Ų65.830%0.29733%0.333SS..SBendtrans-79.8-12.5-17860.90000114.9I249 Q252 C569 Q570 C571I249-C562 HydrophobicContact CB-CB 3.76Å; I249-C562 HydrophobicContact CD1-CB 4.08Å; I249-C562 HydrophobicContact CG2-CB 3.64Å; Q252-C562 PolarHBondContact OE1-SG 2.86Å; C562-C569 PolarHBondContact SG-O 3.46Å; C562-Q570 VanDerWaalsContact SG-C 3.56Å; C562-C571 HydrophobicContact CB-CB 3.89Å; C562-C571 WeakPolarHBondContact CB-SG 3.47Å; C562-C571 WeakPolarHBondContact SG-CB 3.47Å; C562-C571 PolarHBondContact SG-N 2.87Å; C562-C571 VanDerWaalsContact SG-N 3.43Å; C562-C571 CovalentContact SG-SG 2.01Å; C562-C571 PolarHBondContact SG-SG 3.13Å
563S87.4Confident88.9Confident37 Ų3770.4 Ų70.426%0.25935%0.354SS..SBendtrans-130-131.6175.360.10000109.7C561 C569 Q570C561-S563 VanDerWaalsContact C-N 3.31Å; C561-S563 PolarHBondContact O-N 3.49Å; S563-C569 WeakPolarHBondContact OG-CA 3.28Å; S563-Q570 WeakPolarHBondContact CB-O 3.47Å; S563-Q570 PolarHBondContact OG-N 3.21Å; S563-Q570 VanDerWaalsContact OG-N 3.08Å; S563-Q570 PolarHBondContact OG-O 3Å
564T83.6Confident86.6Confident64 Ų6472.5 Ų72.539%0.39337%0.368SS..  trans-108.4155173.366.20000111T566 Q567 L568 C569T564-T566 PolarHBondContact O-N 2.93Å; T564-T566 PolarHBondContact OG1-OG1 2.92Å; T564-Q567 CarbonylContact O-C 3.32Å; T564-Q567 WeakPolarHBondContact O-CA 3.29Å; T564-Q567 PolarHBondContact O-N 3.15Å; T564-Q567 WeakPolarHBondContact OG1-CG 3.45Å; T564-Q567 PolarHBondContact OG1-N 3.33Å; T564-L568 PolarHBondContact O-N 3.21Å; T564-C569 PolarHBondContact O-N 2.92Å; T564-C569 VanDerWaalsContact O-N 3.09Å
565F79.9Confident84Confident122 Ų12280.5 Ų80.554%0.53541%0.405SS..G310 helixtrans-57.8-31.8171-77.6-77.2000112.7Q559 Q567 L568Q559-F565 HydrophobicContact CB-CE1 4.16Å; Q559-F565 HydrophobicContact CB-CZ 3.92Å; Q559-F565 HydrophobicContact CG-CE1 3.8Å; Q559-F565 HydrophobicContact CG-CZ 3.99Å; F565-Q567 PolarHBondContact O-N 2.96Å; F565-L568 PolarHBondContact O-N 3.37Å; F565-L568 VanDerWaalsContact O-N 3.08Å
566T79.5Confident83.3Confident134 Ų13482.7 Ų82.782%0.82242%0.417SS*.G310 helixtrans-67.6-23.6174.951.20000113T564 L568T564-T566 PolarHBondContact O-N 2.93Å; T564-T566 PolarHBondContact OG1-OG1 2.92Å; T566-L568 VanDerWaalsContact C-N 3.35Å
567Q79.7Confident82.8Confident117 Ų11783.7 Ų83.755%0.54742%0.418SS..G310 helixtrans-96.715.1172.9-67.9174.8-23.700112.1T564 F565 C569 Q570T564-Q567 CarbonylContact O-C 3.32Å; T564-Q567 WeakPolarHBondContact O-CA 3.29Å; T564-Q567 PolarHBondContact O-N 3.15Å; T564-Q567 WeakPolarHBondContact OG1-CG 3.45Å; T564-Q567 PolarHBondContact OG1-N 3.33Å; F565-Q567 PolarHBondContact O-N 2.96Å; Q567-C569 PolarHBondContact O-N 3.31Å; Q567-Q570 PolarHBondContact O-N 3.32Å
568L83.9Confident82.1Confident75 Ų7579.5 Ų79.539%0.39341%0.407SS..THydrogen-bonded Turntrans54.432-178.5-62.3173000113.7I235 Y238 T564 F565 T566 Q570I235-L568 HydrophobicContact CD1-CD2 3.84Å; I235-L568 HydrophobicContact CG1-CD2 4.31Å; Y238-L568 WeakPolarHBondContact CB-O 3.26Å; Y238-L568 HydrophobicContact CD1-CB 4.39Å; T564-L568 PolarHBondContact O-N 3.21Å; F565-L568 PolarHBondContact O-N 3.37Å; F565-L568 VanDerWaalsContact O-N 3.08Å; T566-L568 VanDerWaalsContact C-N 3.35Å; L568-Q570 HydrophobicContact CB-CG 4.29Å; L568-Q570 PolarHBondContact O-N 3.2Å; L568-Q570 VanDerWaalsContact O-N 3.15Å
569C86.8Confident81.2Confident1 Ų184.2 Ų84.21%0.00743%0.431CS..THydrogen-bonded Turntrans53.934178.6-56.20000113.5Q252 C561 C562 S563 T564 Q567Q252-C569 WeakPolarHBondContact CB-O 3.44Å; Q252-C569 HydrophobicContact CG-CB 4.49Å; Q252-C569 WeakPolarHBondContact CG-O 3.36Å; Q252-C569 PolarHBondContact OE1-O 3.46Å; Q252-C569 VanDerWaalsContact OE1-O 3.09Å; C561-C569 HydrophobicContact CB-CB 3.86Å; C561-C569 WeakPolarHBondContact CB-SG 3.37Å; C561-C569 WeakPolarHBondContact SG-CA 3.37Å; C561-C569 WeakPolarHBondContact SG-CB 3.28Å; C561-C569 CovalentContact SG-SG 2.03Å; C561-C569 PolarHBondContact SG-SG 3.41Å; C562-C569 PolarHBondContact SG-O 3.46Å; S563-C569 WeakPolarHBondContact OG-CA 3.28Å; T564-C569 PolarHBondContact O-N 2.92Å; T564-C569 VanDerWaalsContact O-N 3.09Å; Q567-C569 PolarHBondContact O-N 3.31Å
570Q90.8Very high80.2Confident92 Ų9289.2 Ų89.243%0.4346%0.457SS..  trans-85.7137.8-178-67.41773.500112.3Y238 Q252 C562 S563 Q567 L568Y238-Q570 HydrophobicContact CD1-CG 3.64Å; Y238-Q570 HydrophobicContact CE1-CG 3.62Å; Q252-Q570 VanDerWaalsContact O-CA 3.28Å; Q252-Q570 WeakPolarHBondContact O-CA 3.4Å; C562-Q570 VanDerWaalsContact SG-C 3.56Å; S563-Q570 WeakPolarHBondContact CB-O 3.47Å; S563-Q570 PolarHBondContact OG-N 3.21Å; S563-Q570 VanDerWaalsContact OG-N 3.08Å; S563-Q570 PolarHBondContact OG-O 3Å; Q567-Q570 PolarHBondContact O-N 3.32Å; L568-Q570 HydrophobicContact CB-CG 4.29Å; L568-Q570 PolarHBondContact O-N 3.2Å; L568-Q570 VanDerWaalsContact O-N 3.15Å
571C90.7Very high79.3Confident30 Ų3094.7 Ų94.720%0.20349%0.485CS..EExtended strand (participates in β ladder)trans-161.9151.3168.255.40000112.1Q252 C562Q252-C571 PolarHBondContact N-O 3.43Å; Q252-C571 PolarHBondContact O-N 3.37Å; C562-C571 HydrophobicContact CB-CB 3.89Å; C562-C571 WeakPolarHBondContact CB-SG 3.47Å; C562-C571 WeakPolarHBondContact SG-CB 3.47Å; C562-C571 PolarHBondContact SG-N 2.87Å; C562-C571 VanDerWaalsContact SG-N 3.43Å; C562-C571 CovalentContact SG-SG 2.01Å; C562-C571 PolarHBondContact SG-SG 3.13Å
572Q85.4Confident78.3Confident140 Ų14099 Ų9965%0.65450%0.503SS*.EExtended strand (participates in β ladder)trans-133112.5162.8-70.9-175.4-42.800106.8E251E251-Q572 HydrophobicContact CG-CG 4.18Å
573Q72.4Confident77.3Confident116 Ų116103.2 Ų103.254%0.54252%0.518SS..  trans-90.2101.3170.2-74.5-171.1-1100108.8V250 K575V250-Q573 PolarHBondContact O-N 3.2Å; Q573-K575 PolarHBondContact O-N 2.87Å
574D45.1Very low76.4Confident156 Ų156108.8 Ų108.883%0.83454%0.54SS*.  trans-68.7106.7162.1-80.2-25.2000108.5
575K39.5Very low75.8Confident258 Ų258112.8 Ų112.8100%1.12255%0.553SS**  trans-142.50159.6-74-164.3178.8177.10111.3Q573Q573-K575 PolarHBondContact O-N 2.87Å

Retrieved 575 of 575 residues in 1248.5 ms (Link to these results)